BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P41209 (172 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5D43-A nrPDB 343 2e-95 2GGM-A nrPDB 292 5e-80 2OBH-A nrPDB 249 3e-67 3KF9-A nrPDB 241 1e-64 3QRX-A nrPDB 222 8e-59 3FWC-A nrPDB 161 1e-40 1ZMZ-A nrPDB 161 1e-40 1M39-A nrPDB 155 6e-39 3EK4-A nrPDB 151 1e-37 4IL1-A nrPDB 150 3e-37 4OY4-A nrPDB 150 3e-37 3U0K-A nrPDB 150 4e-37 6O20-F nrPDB 148 9e-37 3WFN-B nrPDB 148 9e-37 2F2P-A nrPDB 148 1e-36 4E53-A nrPDB 148 1e-36 1CLM-A nrPDB 147 2e-36 5A2H-A nrPDB 147 2e-36 2N6A-A nrPDB 146 4e-36 6HCS-A nrPDB 145 6e-36 5I0I-E nrPDB 144 1e-35 5UKG-A nrPDB 144 2e-35 4I2Y-A nrPDB 144 2e-35 2K2I-A nrPDB 142 5e-35 1GGZ-A nrPDB 141 2e-34 2L1W-A nrPDB 139 6e-34 5ZOR-A nrPDB 136 5e-33 2LMV-A nrPDB 122 1e-28 2AMI-A nrPDB 120 3e-28 4DS7-A nrPDB 119 6e-28 2LHI-A nrPDB 118 1e-27 1LKJ-A nrPDB 118 1e-27 2TN4-A nrPDB 111 2e-25 1TOP-A nrPDB 108 8e-25 1OQP-A nrPDB 105 1e-23 2LHH-A nrPDB 104 2e-23 1DTL-A nrPDB 101 2e-22 2LC5-A nrPDB 97 4e-21 2JOJ-A nrPDB 94 3e-20 4WPX-A nrPDB 94 4e-20 5Z1Q-A nrPDB 93 6e-20 3IFK-A nrPDB 90 4e-19 4MVF-A nrPDB 84 4e-17 3PM8-A nrPDB 82 8e-17 2LAP-A nrPDB 82 2e-16 3J04-B nrPDB 81 2e-16 2JNF-A nrPDB 80 4e-16 1W7I-B nrPDB 79 1e-15 1S6I-A nrPDB 78 2e-15 3DTP-E nrPDB 77 5e-15 2RO9-A nrPDB 77 5e-15 2I08-A nrPDB 77 5e-15 2M29-A nrPDB 76 6e-15 1FW4-A nrPDB 76 8e-15 2M5E-A nrPDB 76 8e-15 2RO8-A nrPDB 75 1e-14 2KN2-A nrPDB 75 1e-14 2ROB-A nrPDB 75 2e-14 2OS8-B nrPDB 74 4e-14 2EC6-B nrPDB 73 6e-14 2KZ2-A nrPDB 73 6e-14 2BL0-C nrPDB 73 8e-14 2AAO-A nrPDB 73 8e-14 5COC-A nrPDB 72 1e-13 1TNP-A nrPDB 72 1e-13 1TRF-A nrPDB 72 2e-13 2KSZ-A nrPDB 71 2e-13 3TS5-B nrPDB 71 3e-13 5H53-C nrPDB 70 5e-13 1DFK-Y nrPDB 70 5e-13 5H7D-E nrPDB 70 5e-13 1B7T-Y nrPDB 70 5e-13 2BL0-B nrPDB 70 6e-13 1F55-A nrPDB 69 1e-12 3JAX-C nrPDB 69 1e-12 1SR6-C nrPDB 68 2e-12 3I5H-B nrPDB 68 2e-12 3JBH-C nrPDB 67 3e-12 4Q57-A nrPDB 67 3e-12 1GGW-A nrPDB 67 5e-12 5B7X-A nrPDB 66 6e-12 5VLN-A nrPDB 65 1e-11 4GJF-A nrPDB 65 2e-11 2N7L-C nrPDB 64 2e-11 1N2D-A nrPDB 64 2e-11 2W4G-C nrPDB 64 3e-11 2HF5-A nrPDB 64 5e-11 2LV7-A nrPDB 63 5e-11 5TBY-E nrPDB 63 8e-11 3HZT-A nrPDB 62 2e-10 6FSA-D nrPDB 61 2e-10 2N8Y-A nrPDB 61 2e-10 4ORC-B nrPDB 61 2e-10 4D1E-A nrPDB 61 2e-10 4JWQ-A nrPDB 61 2e-10 3KHE-A nrPDB 61 3e-10 5TBY-C nrPDB 61 3e-10 1O1A-B nrPDB 59 9e-10 1I84-U nrPDB 59 9e-10 3NCG-A nrPDB 59 1e-09 3Q5I-A nrPDB 58 2e-09 3I5I-C nrPDB 58 2e-09 2M8U-A nrPDB 57 3e-09 3H4S-E nrPDB 57 3e-09 3O4Y-A nrPDB 57 4e-09 2B1U-A nrPDB 57 4e-09 5B8I-B nrPDB 57 5e-09 1C7W-A nrPDB 56 7e-09 1SJJ-A nrPDB 56 8e-09 5JN2-A nrPDB 55 1e-08 4RGJ-A nrPDB 55 2e-08 2K2A-A nrPDB 55 2e-08 5H53-B nrPDB 54 4e-08 3K21-A nrPDB 53 6e-08 5E37-A nrPDB 53 7e-08 2K7B-A nrPDB 52 1e-07 3LIJ-A nrPDB 51 2e-07 3L19-A nrPDB 51 2e-07 1Y1X-A nrPDB 51 3e-07 2FCE-A nrPDB 50 4e-07 5W1A-B nrPDB 50 4e-07 1DGU-A nrPDB 50 6e-07 2LM5-A nrPDB 50 7e-07 4YZB-A nrPDB 49 8e-07 1QX2-A nrPDB 49 8e-07 4N5X-A nrPDB 49 9e-07 4ZCV-A nrPDB 49 1e-06 4AOM-A nrPDB 49 2e-06 3TZ1-A nrPDB 48 2e-06 1OZS-A nrPDB 48 3e-06 1GJY-A nrPDB 47 4e-06 4OCI-A nrPDB 47 4e-06 3AAJ-A nrPDB 47 5e-06 2K7C-A nrPDB 46 7e-06 2AUC-A nrPDB 46 8e-06 2M97-A nrPDB 46 1e-05 1JC2-A nrPDB 45 2e-05 1JUO-A nrPDB 45 2e-05 5MWC-D nrPDB 45 2e-05 5MRA-A nrPDB 45 2e-05 1S6J-A nrPDB 45 2e-05 1JF0-A nrPDB 44 3e-05 2VTG-A nrPDB 44 3e-05 5I2L-A nrPDB 44 3e-05 5OTJ-D nrPDB 44 3e-05 2LVK-A nrPDB 44 4e-05 3BOW-B nrPDB 44 5e-05 2R2I-A nrPDB 43 7e-05 1KFX-S nrPDB 43 7e-05 2G2B-A nrPDB 42 2e-04 1QXP-A nrPDB 42 2e-04 2D58-A nrPDB 41 2e-04 2BEC-A nrPDB 41 2e-04 2E30-A nrPDB 41 3e-04 2OPO-A nrPDB 41 3e-04 1TIZ-A nrPDB 40 3e-04 1WY9-A nrPDB 40 4e-04 3PAT-A nrPDB 40 4e-04 1S36-A nrPDB 40 4e-04 1H4B-A nrPDB 40 5e-04 2I94-A nrPDB 40 5e-04 5T7C-A nrPDB 39 8e-04 2G9B-A nrPDB 39 0.001 3KPX-A nrPDB 39 0.001 1F4Q-A nrPDB 39 0.001 3E3R-A nrPDB 39 0.001 1BJF-A nrPDB 38 0.002 5VT9-A nrPDB 38 0.003 4GFT-A nrPDB 37 0.003 1A75-A nrPDB 37 0.003 2M7L-A nrPDB 37 0.003 1NP8-A nrPDB 37 0.003 2D8N-A nrPDB 37 0.004 5XND-A nrPDB 37 0.005 2NLN-A nrPDB 37 0.005 2JNX-A nrPDB 37 0.005 4PAL-A nrPDB 37 0.005 2L2E-A nrPDB 37 0.006 5JOL-A nrPDB 36 0.007 5JOJ-A nrPDB 36 0.007 3SIA-A nrPDB 36 0.007 2KYF-A nrPDB 36 0.008 1BU3-A nrPDB 36 0.009 2KQY-A nrPDB 35 0.012 5CPV-A nrPDB 35 0.015 3DD4-A nrPDB 35 0.016 5E1J-A nrPDB 35 0.016 3AKA-A nrPDB 35 0.017 1YX7-A nrPDB 35 0.018 2GGZ-A nrPDB 35 0.018 2JUL-A nrPDB 35 0.019 6EPA-A nrPDB 35 0.023 1TTX-A nrPDB 35 0.023 2NA0-A nrPDB 35 0.024 1V1G-A nrPDB 34 0.025 1S6C-A nrPDB 34 0.026 1S1E-A nrPDB 34 0.027 4C0K-A nrPDB 34 0.033 2M1U-A nrPDB 34 0.034 1IJ5-A nrPDB 34 0.038 4OKH-A nrPDB 34 0.042 5ZGM-A nrPDB 33 0.042 6AGI-A nrPDB 33 0.043 5PAL-A nrPDB 33 0.050 1JFJ-A nrPDB 33 0.060 5M6C-E nrPDB 33 0.075 3CS1-A nrPDB 32 0.095 4P5X-A nrPDB 32 0.097 5CUY-A nrPDB 32 0.10 5ZH6-A nrPDB 32 0.12 2ZFD-A nrPDB 32 0.12 4P5W-A nrPDB 32 0.12 1UHN-A nrPDB 32 0.15 6IIE-A nrPDB 32 0.17 2LCP-A nrPDB 31 0.28 1KQV-A nrPDB 30 0.37 1RTP-1 nrPDB 30 0.45 5VE9-A nrPDB 30 0.47 1BOD-A nrPDB 30 0.49 2HPS-A nrPDB 30 0.57 1G33-A nrPDB 30 0.63 4NQG-A nrPDB 30 0.64 2NCO-A nrPDB 30 0.69 5YPX-A nrPDB 29 0.81 4TR2-A nrPDB 29 0.85 2JTT-A nrPDB 29 0.98 1CB1-A nrPDB 29 1.2 1RK9-A nrPDB 28 2.2 1NYA-A nrPDB 28 2.2 2E6W-A nrPDB 28 2.5 2LVV-A nrPDB 28 2.9 1KFU-L nrPDB 27 3.2 1JBA-A nrPDB 27 3.2 2Q4U-A nrPDB 27 3.3 4YBH-B nrPDB 27 3.5 4NSC-A nrPDB 27 3.6 1SL8-A nrPDB 27 3.7 2M7M-A nrPDB 27 3.8 2MBX-A nrPDB 27 3.9 5N1Q-C nrPDB 27 3.9 5XOP-A nrPDB 27 4.0 3DF0-A nrPDB 27 4.5 5CSF-A nrPDB 27 5.1 6AGH-A nrPDB 27 5.8 1UHK-A nrPDB 27 6.5 4OVR-A nrPDB 27 6.6 6MI5-X nrPDB 26 7.9 2MA2-A nrPDB 26 8.1 6EAZ-A nrPDB 26 9.8 >5D43-A nrPDB Length = 178 Score = 343 bits (880), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 172/172 (100%), Positives = 172/172 (100%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL Sbjct: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK Sbjct: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY Sbjct: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 >2GGM-A nrPDB Length = 172 Score = 292 bits (748), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 141/172 (81%), Positives = 165/172 (95%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 MAS F+K+N+AS+S ++++ PKPELTE+QKQE+REAFDLFD+DG+GTIDVKELKVAMRAL Sbjct: 1 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL 60 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GFEP+KEE+KKMISE+DKE TGK++F DFL VMTQKM+EKDTKEEILKAF+LFDDDETGK Sbjct: 61 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK 120 Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 ISFKNLKRVA ELGE+LTDEELQEMIDEADRDGDGEV+E+EFL+IMKKT+LY Sbjct: 121 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172 >2OBH-A nrPDB Length = 143 Score = 249 bits (637), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 124/143 (86%), Positives = 139/143 (97%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 TE+QKQE+REAFDLFD+DG+GTIDVKELKVAMRALGFEP+KEE+KKMISE+DKE TGK++ Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 60 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F DFL VMTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEM Sbjct: 61 FGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEM 120 Query: 146 IDEADRDGDGEVNEEEFLKIMKK 168 IDEADRDGDGEV+E+EFL+IMKK Sbjct: 121 IDEADRDGDGEVSEQEFLRIMKK 143 >3KF9-A nrPDB Length = 149 Score = 241 bits (615), Expect = 1e-64, Method: Compositional matrix adjust. Identities = 117/148 (79%), Positives = 138/148 (93%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+QKQE+REAFDLFD+DGSGTID KELKVAMRALGFEP+KEE+KKMI+++DK+ +G I Sbjct: 2 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTI 61 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F +FL +MT KM E+D++EEI+KAFRLFDDDETGKISFKNLKRVA ELGE++TDEELQE Sbjct: 62 DFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQE 121 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKTNLY 172 MIDEADRDGDGEVNEEEF +IMKKT+L+ Sbjct: 122 MIDEADRDGDGEVNEEEFFRIMKKTSLF 149 >3QRX-A nrPDB Length = 169 Score = 222 bits (565), Expect = 8e-59, Method: Compositional matrix adjust. Identities = 110/169 (65%), Positives = 142/169 (84%), Gaps = 1/169 (0%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 +++ V S +K G + LTE+QKQE+REAFDLFD+DGSGTID KELKVAMRALGFE Sbjct: 2 SYKAKTVVSARRDQKKG-RVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 60 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 P+KEE+KKMISE+DK+ +G I F +FL +MT KM E+D++EEILKAFRLFDDD +G I+ Sbjct: 61 PKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITI 120 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 K+L+RVA ELGE+LT+EELQEMI EADR+ D E++E+EF++IMKKT+L+ Sbjct: 121 KDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKKTSLF 169 >3FWC-A nrPDB Length = 161 Score = 161 bits (407), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 84/147 (57%), Positives = 107/147 (72%), Gaps = 1/147 (0%) Query: 20 GP-KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDK 78 GP EL E+QKQE+ EAF LFD + G +D ELKVAM+ALGFE K E+ +I E D Sbjct: 11 GPLNSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDS 70 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLT 138 E + ++DF VM +K+ ++D +EI +AF+LFDDD TGKIS KNL+RVA ELGE+LT Sbjct: 71 EGRHLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLT 130 Query: 139 DEELQEMIDEADRDGDGEVNEEEFLKI 165 DEEL+ MI+E D DGDGE+NE EF+ I Sbjct: 131 DEELRAMIEEFDLDGDGEINENEFIAI 157 Score = 52.8 bits (125), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 41/70 (58%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L D E++ AF LFD D +G I +K L+ + LG EE++ MI E D + G+I Sbjct: 90 LKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEELRAMIEEFDLDGDGEI 149 Query: 85 SFNDFLAVMT 94 + N+F+A+ T Sbjct: 150 NENEFIAICT 159 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 35/64 (54%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K+EI +AF LFD + G + + LK LG L E+ ++IDE D +G + ++F Sbjct: 22 KQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGRHLMKYDDF 81 Query: 163 LKIM 166 +M Sbjct: 82 YIVM 85 >1ZMZ-A nrPDB Length = 98 Score = 161 bits (407), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 74/98 (75%), Positives = 92/98 (93%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 MAS F+K+N+AS+S ++++ PKPELTE+QKQE+REAFDLFD+DG+GTIDVKELKVAMRAL Sbjct: 1 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL 60 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMA 98 GFEP+KEE+KKMISE+DKE TGK++F DFL VMTQKM+ Sbjct: 61 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMS 98 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 29/64 (45%), Positives = 40/64 (62%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K+EI +AF LFD D TG I K LK LG EE+++MI E D++G G++N +F Sbjct: 30 KQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMNFGDF 89 Query: 163 LKIM 166 L +M Sbjct: 90 LTVM 93 >1M39-A nrPDB Length = 89 Score = 155 bits (393), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 77/89 (86%), Positives = 86/89 (96%) Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 ++F DFL VMTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQ Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQ 60 Query: 144 EMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 EMIDEADRDGDGEV+E+EFL+IMKKT+LY Sbjct: 61 EMIDEADRDGDGEVSEQEFLRIMKKTSLY 89 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 27/66 (40%), Positives = 41/66 (62%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D K+E+ +AF LFD D +G I K LK + LG EE+++MI E D++ G++S Sbjct: 18 DTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQ 77 Query: 88 DFLAVM 93 +FL +M Sbjct: 78 EFLRIM 83 >3EK4-A nrPDB Length = 451 Score = 151 bits (382), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 78/153 (50%), Positives = 104/153 (67%) Query: 14 SYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMI 73 +K + + +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI Sbjct: 296 GHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI 355 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 +EVD + G I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V L Sbjct: 356 NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL 415 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 GE LTDEE+ EMI EAD DGDG+VN EEF+++M Sbjct: 416 GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 45/69 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 383 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 442 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 443 EFVQMMTAK 451 Score = 56.6 bits (135), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 29/64 (45%), Positives = 41/64 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 314 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 373 Query: 165 IMKK 168 +M + Sbjct: 374 MMAR 377 >4IL1-A nrPDB Length = 823 Score = 150 bits (379), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMM 146 Score = 67.8 bits (164), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 50/154 (32%), Positives = 80/154 (51%), Gaps = 19/154 (12%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 81 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140 Query: 88 DFLAVMTQKMAEKDTKEEI------LKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 +F+ +MT K L+ FD DE ++ K K++ + SL+ EE Sbjct: 141 EFVQMMTAKGGGGGGGGGGNEASYPLEMCSHFDADEIKRLG-KRFKKLDLDNSGSLSVEE 199 Query: 142 ------------LQEMIDEADRDGDGEVNEEEFL 163 +Q +ID D DG+GEV+ +EF+ Sbjct: 200 FMSLPELQQNPLVQRVIDIFDTDGNGEVDFKEFI 233 Score = 62.4 bits (150), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 87/150 (58%), Gaps = 9/150 (6%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D+ + + + F D D SG++ V+E +++ L P ++++I D + G++ F Sbjct: 175 DEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFK 230 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMI 146 +F+ ++Q + D ++++ AFR++D D+ G IS L +V + G +L D +LQ+++ Sbjct: 231 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 290 Query: 147 DE----ADRDGDGEVNEEEFLKIMKKTNLY 172 D+ AD+DGDG ++ EEF ++ +++ Sbjct: 291 DKTIINADKDGDGRISFEEFCAVVGGLDIH 320 Score = 59.7 bits (143), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 33/75 (44%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Query: 97 MAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 154 DGEVNEEEFLKIMKK 168 +G ++ EFL +M + Sbjct: 61 NGTIDFPEFLTMMAR 75 >4OY4-A nrPDB Length = 415 Score = 150 bits (379), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 11 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGT 70 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 130 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 131 EMIREADIDGDGQVNYEEFVQMM 153 Score = 58.5 bits (140), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 30/64 (46%), Positives = 41/64 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DGDG ++ EFL Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLT 78 Query: 165 IMKK 168 +M + Sbjct: 79 MMAR 82 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 28/70 (40%), Positives = 46/70 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 88 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 147 Query: 88 DFLAVMTQKM 97 +F+ +MT K+ Sbjct: 148 EFVQMMTAKL 157 >3U0K-A nrPDB Length = 442 Score = 150 bits (378), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 80/154 (51%), Positives = 105/154 (68%), Gaps = 3/154 (1%) Query: 16 KRKVGPKP---ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKM 72 K+ G +P +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ M Sbjct: 286 KKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDM 345 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 I+EVD + G I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V Sbjct: 346 INEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTN 405 Query: 133 LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 LGE LTDEE+ EMI EAD DGDG+VN EEF+++M Sbjct: 406 LGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 30/64 (46%), Positives = 41/64 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DGDG ++ EFL Sbjct: 305 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLI 364 Query: 165 IMKK 168 +M + Sbjct: 365 MMAR 368 Score = 57.0 bits (136), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 45/69 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 374 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 433 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 434 EFVQMMTAK 442 >6O20-F nrPDB Length = 169 Score = 148 bits (374), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 24 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 83 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 84 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 143 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 144 EMIREADIDGDGQVNYEEFVQMM 166 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 33/76 (43%), Positives = 49/76 (64%), Gaps = 3/76 (3%) Query: 96 KMAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 MA++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D D Sbjct: 20 HMADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD 79 Query: 153 GDGEVNEEEFLKIMKK 168 G+G ++ EFL +M + Sbjct: 80 GNGTIDFPEFLTMMAR 95 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 45/69 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 101 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 160 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 161 EFVQMMTAK 169 >3WFN-B nrPDB Length = 182 Score = 148 bits (374), Expect = 9e-37, Method: Compositional matrix adjust. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 10 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 69 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 70 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 129 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 130 EMIREADIDGDGQVNYEEFVQMM 152 Score = 57.8 bits (138), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 33/75 (44%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Query: 97 MAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 7 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 66 Query: 154 DGEVNEEEFLKIMKK 168 +G ++ EFL +M + Sbjct: 67 NGTIDFPEFLTMMAR 81 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 45/69 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 87 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 146 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 147 EFVQMMTAK 155 >2F2P-A nrPDB Length = 179 Score = 148 bits (374), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMM 146 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 33/75 (44%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Query: 97 MAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 154 DGEVNEEEFLKIMKK 168 +G ++ EFL +M + Sbjct: 61 NGTIDFPEFLTMMAR 75 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 45/69 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 81 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 141 EFVQMMTAK 149 >4E53-A nrPDB Length = 185 Score = 148 bits (373), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 11 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 70 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 130 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 131 EMIREADIDGDGQVNYEEFVQMM 153 Score = 57.8 bits (138), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 56/100 (56%), Gaps = 7/100 (7%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 88 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 147 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLK 127 +F+ +MT K +I +FR G I+ K LK Sbjct: 148 EFVQMMTAKGGGGGAATKIQASFR-------GHITRKKLK 180 Score = 57.4 bits (137), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 33/75 (44%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Query: 97 MAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 8 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 67 Query: 154 DGEVNEEEFLKIMKK 168 +G ++ EFL +M + Sbjct: 68 NGTIDFPEFLTMMAR 82 >1CLM-A nrPDB Length = 148 Score = 147 bits (372), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 75/143 (52%), Positives = 102/143 (71%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ELTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 ELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL++M +KM E+D++EE+++AF++FD D G IS L+ V LGE LTD+E+ Sbjct: 63 IDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVD 122 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG +N EEF+++M Sbjct: 123 EMIREADIDGDGHINYEEFVRMM 145 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 32/74 (43%), Positives = 48/74 (64%), Gaps = 3/74 (4%) Query: 98 AEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 A++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+ Sbjct: 1 AQELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 155 GEVNEEEFLKIMKK 168 G ++ EFL +M + Sbjct: 61 GTIDFPEFLSLMAR 74 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 43/70 (61%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D ++E+ EAF +FD DG+G I EL+ M LG + +E+ +MI E D + G I++ Sbjct: 79 QDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINY 138 Query: 87 NDFLAVMTQK 96 +F+ +M K Sbjct: 139 EEFVRMMVSK 148 >5A2H-A nrPDB Length = 149 Score = 147 bits (371), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 75/143 (52%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LT+DQ E +EAF LFD DG G I KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EE+ +AFR+FD D+ G IS L+ V LGE LTDEE+ Sbjct: 64 IDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG++N EEF+K+M Sbjct: 124 EMIREADVDGDGQINYEEFVKVM 146 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 32/75 (42%), Positives = 48/75 (64%), Gaps = 3/75 (4%) Query: 97 MAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA++ T ++I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 1 MADQLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 154 DGEVNEEEFLKIMKK 168 +G ++ EFL +M + Sbjct: 61 NGTIDFPEFLNLMAR 75 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 43/69 (62%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+ +MI E D + G+I++ Sbjct: 81 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 140 Query: 88 DFLAVMTQK 96 +F+ VM K Sbjct: 141 EFVKVMMAK 149 >2N6A-A nrPDB Length = 173 Score = 146 bits (369), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 76/141 (53%), Positives = 98/141 (69%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 TE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 66 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ EM Sbjct: 67 FPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 126 Query: 146 IDEADRDGDGEVNEEEFLKIM 166 I EAD DGDG+VN EEF+++M Sbjct: 127 IREADIDGDGQVNYEEFVQMM 147 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 44/67 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 82 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 141 Query: 88 DFLAVMT 94 +F+ +MT Sbjct: 142 EFVQMMT 148 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 29/64 (45%), Positives = 41/64 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 13 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 72 Query: 165 IMKK 168 +M + Sbjct: 73 MMAR 76 >6HCS-A nrPDB Length = 167 Score = 145 bits (367), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 76/143 (53%), Positives = 99/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ LGE LTDEE+ Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMM 146 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 28/70 (40%), Positives = 46/70 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 81 DSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 140 Query: 88 DFLAVMTQKM 97 +F+ +MT K+ Sbjct: 141 EFVQMMTAKL 150 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 33/75 (44%), Positives = 49/75 (65%), Gaps = 3/75 (4%) Query: 97 MAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 1 MADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 60 Query: 154 DGEVNEEEFLKIMKK 168 +G ++ EFL +M + Sbjct: 61 NGTIDFPEFLTMMAR 75 >5I0I-E nrPDB Length = 145 Score = 144 bits (364), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 76/143 (53%), Positives = 99/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF L D DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 2 QLTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 61 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 62 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 121 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 122 EMIREADIDGDGQVNYEEFVQMM 144 Score = 56.6 bits (135), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 44/67 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 79 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 138 Query: 88 DFLAVMT 94 +F+ +MT Sbjct: 139 EFVQMMT 145 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 28/64 (43%), Positives = 40/64 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF L D D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 69 Query: 165 IMKK 168 +M + Sbjct: 70 MMAR 73 >5UKG-A nrPDB Length = 419 Score = 144 bits (363), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 74/143 (51%), Positives = 98/143 (68%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 274 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGT 333 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 F +FL +M +KM+ + T+EEI +AFR+FD D G I L+ V +LGE LTDEE+ Sbjct: 334 FDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVD 393 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI AD DGDG+VN EEF+++M Sbjct: 394 EMIRVADIDGDGQVNYEEFVQMM 416 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 31/68 (45%), Positives = 41/68 (60%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DGDG + EFL Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLT 341 Query: 165 IMKKTNLY 172 +M + Y Sbjct: 342 MMARKMSY 349 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 26/66 (39%), Positives = 42/66 (63%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 +E+REAF +FD DG+G I EL+ M LG + EE+ +MI D + G++++ +F+ Sbjct: 354 EEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEFV 413 Query: 91 AVMTQK 96 +MT K Sbjct: 414 QMMTAK 419 >4I2Y-A nrPDB Length = 421 Score = 144 bits (363), Expect = 2e-35, Method: Compositional matrix adjust. Identities = 74/143 (51%), Positives = 98/143 (68%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 276 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGT 335 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 F +FL +M +KM + D++EEI +AFR+FD D G I L+ V +LGE LTDEE+ Sbjct: 336 FDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVD 395 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI AD DGDG+VN EEF+++M Sbjct: 396 EMIRVADIDGDGQVNYEEFVQMM 418 Score = 56.6 bits (135), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 30/64 (46%), Positives = 40/64 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DGDG + EFL Sbjct: 284 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLT 343 Query: 165 IMKK 168 +M + Sbjct: 344 MMAR 347 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 44/69 (63%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI D + G++++ Sbjct: 353 DSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYE 412 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 413 EFVQMMTAK 421 >2K2I-A nrPDB Length = 79 Score = 142 bits (359), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 71/79 (89%), Positives = 78/79 (98%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 TQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEMIDEADRDG Sbjct: 1 TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDG 60 Query: 154 DGEVNEEEFLKIMKKTNLY 172 DGEV+E+EFL+IMKKT+LY Sbjct: 61 DGEVSEQEFLRIMKKTSLY 79 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 27/66 (40%), Positives = 41/66 (62%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D K+E+ +AF LFD D +G I K LK + LG EE+++MI E D++ G++S Sbjct: 8 DTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQ 67 Query: 88 DFLAVM 93 +FL +M Sbjct: 68 EFLRIM 73 >1GGZ-A nrPDB Length = 148 Score = 141 bits (355), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 69/143 (48%), Positives = 98/143 (68%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG G I +EL MR+LG P + E++ M+SE+D++ G Sbjct: 3 QLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 + F +FL +M +KM + D +EEI +AFR+FD D G +S L+ V LGE L+DEE+ Sbjct: 63 VDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVD 122 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI AD DGDG+VN EEF++++ Sbjct: 123 EMIRAADTDGDGQVNYEEFVRVL 145 Score = 53.5 bits (127), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 25/69 (36%), Positives = 43/69 (62%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G + EL+ M LG + EE+ +MI D + G++++ Sbjct: 80 DNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVDEMIRAADTDGDGQVNYE 139 Query: 88 DFLAVMTQK 96 +F+ V+ K Sbjct: 140 EFVRVLVSK 148 Score = 52.4 bits (124), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 28/64 (43%), Positives = 41/64 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ + L V LG++ T+ EL++M+ E DRDG+G V+ EFL Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLG 70 Query: 165 IMKK 168 +M + Sbjct: 71 MMAR 74 >2L1W-A nrPDB Length = 149 Score = 139 bits (350), Expect = 6e-34, Method: Compositional matrix adjust. Identities = 71/142 (50%), Positives = 102/142 (71%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+Q + +EAF LFD DG G I V+EL +R+L P +EE++ MISEVD + G I Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F++FL++M +K+ + D +EE+ +AF++FD D+ G IS L+ V LGE LTDEE+++ Sbjct: 64 EFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQ 123 Query: 145 MIDEADRDGDGEVNEEEFLKIM 166 MI EAD DGDG+VN EEF+K+M Sbjct: 124 MIKEADLDGDGQVNYEEFVKMM 145 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 28/61 (45%), Positives = 39/61 (63%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +AF LFD D G I+ + L V L ++ T+EELQ+MI E D DG+G + +EFL +M Sbjct: 14 EAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMA 73 Query: 168 K 168 K Sbjct: 74 K 74 >5ZOR-A nrPDB Length = 149 Score = 136 bits (343), Expect = 5e-33, Method: Compositional matrix adjust. Identities = 72/138 (52%), Positives = 102/138 (73%), Gaps = 3/138 (2%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFE--PRKEEMKKMISEVDKEATGKISFND 88 +++REAF+LFD+DGSG ID +E+ +AM+ LGF PR +E+++ + ++ A G I + + Sbjct: 7 EQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPR-DEVERTVRSMNTNANGLIEYGE 65 Query: 89 FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDE 148 F ++ +MA+KD+ EE+LKAF+LFD D+ GKISF NLK VA LGE+ D+ LQEMI E Sbjct: 66 FERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQEMIAE 125 Query: 149 ADRDGDGEVNEEEFLKIM 166 AD DGDGEV+ EEF +M Sbjct: 126 ADEDGDGEVSFEEFKSVM 143 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 27/68 (39%), Positives = 41/68 (60%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D +EV +AF LFD D G I LK + LG P + +++MI+E D++ G++SF Sbjct: 78 DSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQEMIAEADEDGDGEVSFE 137 Query: 88 DFLAVMTQ 95 +F +VM Q Sbjct: 138 EFKSVMMQ 145 Score = 27.7 bits (60), Expect = 2.5, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 35/67 (52%), Gaps = 1/67 (1%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELG-ESLTDEELQEMIDEADRDGDGEVNEE 160 T E+I +AF LFD D +G I + + LG L +E++ + + + +G + Sbjct: 5 TDEQIREAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGLIEYG 64 Query: 161 EFLKIMK 167 EF +++K Sbjct: 65 EFERMVK 71 Score = 26.9 bits (58), Expect = 5.0, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 20/32 (62%) Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +LTDE+++E + D DG G ++ EE MK Sbjct: 3 ALTDEQIREAFNLFDADGSGAIDAEEMALAMK 34 >2LMV-A nrPDB Length = 148 Score = 122 bits (305), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 64/145 (44%), Positives = 96/145 (66%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ELTE+Q E ++AF FD +G+G I +EL MR LG P + E++ +I+E + G+ Sbjct: 3 ELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNGQ 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 ++F +F +M ++M E DT+EE+ +AF++FD D G IS L+ V LGE +TDEE+ Sbjct: 63 LNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEID 122 Query: 144 EMIDEADRDGDGEVNEEEFLKIMKK 168 EMI EAD DGDG +N EEF+ ++ + Sbjct: 123 EMIREADFDGDGMINYEEFVWMISQ 147 Score = 54.3 bits (129), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 44/69 (63%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG G I EL+ M LG + EE+ +MI E D + G I++ Sbjct: 80 DTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEIDEMIREADFDGDGMINYE 139 Query: 88 DFLAVMTQK 96 +F+ +++QK Sbjct: 140 EFVWMISQK 148 >2AMI-A nrPDB Length = 96 Score = 120 bits (301), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 60/94 (63%), Positives = 75/94 (79%), Gaps = 1/94 (1%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 +++ V S +K G + LTE+QKQE+REAFDLFD+DGSGTID KELKVAMRALGFE Sbjct: 4 SYKAKTVVSARRDQKKG-RVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 62 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKM 97 P+KEE+KKMISE+DK+ +G I F +FL +MT KM Sbjct: 63 PKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKM 96 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 30/64 (46%), Positives = 40/64 (62%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K+EI +AF LFD D +G I K LK LG EE+++MI E D+DG G ++ EEF Sbjct: 29 KQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDGSGTIDFEEF 88 Query: 163 LKIM 166 L +M Sbjct: 89 LTMM 92 >4DS7-A nrPDB Length = 147 Score = 119 bits (298), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 60/144 (41%), Positives = 94/144 (65%), Gaps = 1/144 (0%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+Q E +EAF LFD D SG+I EL MR+LG P + E+ +++E+D + I Sbjct: 5 LTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDGNHAI 64 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD E+ E Sbjct: 65 EFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDE 124 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 M+ E DG GE+N ++F ++ K Sbjct: 125 MLREV-SDGSGEINIKQFAALLSK 147 >2LHI-A nrPDB Length = 176 Score = 118 bits (296), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 58/144 (40%), Positives = 95/144 (65%), Gaps = 1/144 (0%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + +I Sbjct: 5 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQI 64 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD E+ + Sbjct: 65 EFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDD 124 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 M+ E DG GE+N ++F ++ K Sbjct: 125 MLREVS-DGSGEINIQQFAALLSK 147 >1LKJ-A nrPDB Length = 146 Score = 118 bits (295), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 58/144 (40%), Positives = 95/144 (65%), Gaps = 1/144 (0%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + +I Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQI 63 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD E+ + Sbjct: 64 EFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDD 123 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 M+ E DG GE+N ++F ++ K Sbjct: 124 MLREV-SDGSGEINIQQFAALLSK 146 >2TN4-A nrPDB Length = 159 Score = 111 bits (277), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 59/150 (39%), Positives = 96/150 (64%), Gaps = 3/150 (2%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 + L+E+ E + AFD+FD+DG G I VKEL MR LG P KEE+ +I EVD++ Sbjct: 7 ARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDG 66 Query: 81 TGKISFNDFLAVMTQKM---AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 +G I F +FL +M ++M A+ ++EE+ + FR+FD + G I + L + GE + Sbjct: 67 SGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEHV 126 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 TDEE++ ++ + D++ DG ++ +EFLK+M+ Sbjct: 127 TDEEIESLMKDGDKNNDGRIDFDEFLKMME 156 >1TOP-A nrPDB Length = 162 Score = 108 bits (271), Expect = 8e-25, Method: Compositional matrix adjust. Identities = 56/146 (38%), Positives = 95/146 (65%), Gaps = 3/146 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+ E + AFD+FD+DG G I KEL MR LG P KEE+ +I EVD++ +G I Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 73 Query: 85 SFNDFLAVMTQKM---AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 F +FL +M ++M A+ ++EE+ FR+FD + G I + L + GE +T+E+ Sbjct: 74 DFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVTEED 133 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMK 167 +++++ ++D++ DG ++ +EFLK+M+ Sbjct: 134 IEDLMKDSDKNNDGRIDFDEFLKMME 159 >1OQP-A nrPDB Length = 77 Score = 105 bits (261), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 50/75 (66%), Positives = 67/75 (89%) Query: 98 AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEV 157 E+D++EEILKAFRLFDDD +G I+ K+L+RVA ELGE+LT+EELQEMI EADR+ D E+ Sbjct: 3 GERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEI 62 Query: 158 NEEEFLKIMKKTNLY 172 +E+EF++IMKKT+L+ Sbjct: 63 DEDEFIRIMKKTSLF 77 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 25/66 (37%), Positives = 44/66 (66%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+ +AF LFD D SGTI +K+L+ + LG +EE+++MI+E D+ +I + Sbjct: 6 DSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDED 65 Query: 88 DFLAVM 93 +F+ +M Sbjct: 66 EFIRIM 71 >2LHH-A nrPDB Length = 128 Score = 104 bits (259), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 50/119 (42%), Positives = 80/119 (67%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + +I Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQI 63 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD EL+ Sbjct: 64 EFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAELE 122 Score = 45.4 bits (106), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 36/61 (59%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +AF LFD D G IS L V LG S ++ E+ ++++E D DG+ ++ EFL +M Sbjct: 14 EAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMS 73 Query: 168 K 168 + Sbjct: 74 R 74 >1DTL-A nrPDB Length = 161 Score = 101 bits (251), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 58/157 (36%), Positives = 99/157 (63%), Gaps = 7/157 (4%) Query: 15 YKRKVGPKPELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMI 73 YK V +LTE+QK E + AFD+F G+I KEL MR LG P EE+++MI Sbjct: 5 YKAAV---EQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMI 61 Query: 74 SEVDKEATGKISFNDFLAVMTQKM---AEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 EVD++ +G + F++FL +M + M ++ ++EE+ FR+FD + G I + LK + Sbjct: 62 DEVDEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIML 121 Query: 131 NELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 GE++T+++++E++ + D++ DG ++ +EFL+ MK Sbjct: 122 QATGETITEDDIEELMKDGDKNNDGRIDYDEFLEFMK 158 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 28/53 (52%), Positives = 36/53 (67%) Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 E G IS K L +V LG++ T EELQEMIDE D DG G V+ +EFL +M ++ Sbjct: 32 EDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDEFLVMMVRS 84 >2LC5-A nrPDB Length = 151 Score = 97.1 bits (240), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 54/145 (37%), Positives = 90/145 (62%), Gaps = 1/145 (0%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 K LT +++QE +EAF LFD D + +EL MRALG P K+++ +++ + DK+ + Sbjct: 5 KKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNS 64 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 GK FL +M + E D+ E+I KAF +FD ++ G IS LK V LGE LT++E Sbjct: 65 GKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTLGEKLTEQE 124 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIM 166 + +++ E + +G +N ++F+K++ Sbjct: 125 VDDLLKEIGVE-EGLINVDDFVKLI 148 >2JOJ-A nrPDB Length = 77 Score = 94.0 bits (232), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 42/77 (54%), Positives = 63/77 (81%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+QKQE++EAFDLFD++ +G+ID ELKVAMRALGF+ +K E+ ++++E D+E G I Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYI 60 Query: 85 SFNDFLAVMTQKMAEKD 101 F+DFL +MT+K+ +D Sbjct: 61 GFDDFLDIMTEKIKNRD 77 Score = 49.7 bits (117), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 26/64 (40%), Positives = 41/64 (64%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K+EI +AF LFD ++TG I + LK LG + E+ E+++E DR+G+G + ++F Sbjct: 6 KQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDDF 65 Query: 163 LKIM 166 L IM Sbjct: 66 LDIM 69 >4WPX-A nrPDB Length = 177 Score = 93.6 bits (231), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 50/154 (32%), Positives = 91/154 (59%), Gaps = 12/154 (7%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-PRKEEMKKMISEVDKEATGK 83 L+++QK + EAF+LFDS+ G + +E + +RALGF+ P+++ ++ + A Sbjct: 20 LSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRPANWP 79 Query: 84 IS------FNDFLAVMTQKMA-----EKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + F Q +A ++D ++E+ +AFRLFD D G I+ +L++V + Sbjct: 80 HDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQ 139 Query: 133 LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 +G ++ D ++Q MI+E D +G G V+E+EFL++M Sbjct: 140 VGNNIPDADIQAMIEEFDSNGKGGVDEDEFLRLM 173 Score = 42.0 bits (97), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 36/69 (52%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + E+R AF LFD DG G I +L+ + +G +++ MI E D G + + Sbjct: 108 DPRDELRRAFRLFDVDGKGMITEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDED 167 Query: 88 DFLAVMTQK 96 +FL +M K Sbjct: 168 EFLRLMMSK 176 >5Z1Q-A nrPDB Length = 95 Score = 92.8 bits (229), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 42/74 (56%), Positives = 62/74 (83%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 EL+E+QKQE++EAFDLFD++ +G+ID ELKVAMRALGF+ +K E+ ++++E D+E G Sbjct: 20 ELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGY 79 Query: 84 ISFNDFLAVMTQKM 97 I F+DFL +MT+K+ Sbjct: 80 IGFDDFLDIMTEKI 93 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 28/72 (38%), Positives = 47/72 (65%), Gaps = 1/72 (1%) Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 Q+++E + K+EI +AF LFD ++TG I + LK LG + E+ E+++E DR+G+ Sbjct: 19 QELSE-EQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGN 77 Query: 155 GEVNEEEFLKIM 166 G + ++FL IM Sbjct: 78 GYIGFDDFLDIM 89 >3IFK-A nrPDB Length = 90 Score = 90.1 bits (222), Expect = 4e-19, Method: Compositional matrix adjust. Identities = 45/88 (51%), Positives = 61/88 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFR 111 I F +FL +M +KM + D++EEI +AFR Sbjct: 63 IDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 32/74 (43%), Positives = 48/74 (64%), Gaps = 3/74 (4%) Query: 98 AEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 A++ T+E+I + AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+ Sbjct: 1 ADQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGN 60 Query: 155 GEVNEEEFLKIMKK 168 G ++ EFL +M + Sbjct: 61 GTIDFPEFLTMMAR 74 >4MVF-A nrPDB Length = 506 Score = 83.6 bits (205), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 45/147 (30%), Positives = 81/147 (55%), Gaps = 3/147 (2%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 L + + +R F D D SGT+ +E+ ++ +G++ ++ +++ ++D A+G+ Sbjct: 353 HLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQ 412 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV--ANELGESLTDEE 141 I + DFLA K KE L F+ FD D GKIS + LKR+ +++ L D+ Sbjct: 413 IHYTDFLAATIDKQTYL-KKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKA 471 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKK 168 + ++ E D +GDGE++ EF+ +M K Sbjct: 472 IDSLLQEVDLNGDGEIDFHEFMLMMSK 498 >3PM8-A nrPDB Length = 197 Score = 82.4 bits (202), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 45/147 (30%), Positives = 81/147 (55%), Gaps = 3/147 (2%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 L + + +R F D D SGT+ +E+ ++ +G++ ++ +++ ++D A+G+ Sbjct: 50 HLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQKIPPDIHQVLRDIDSNASGQ 109 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV--ANELGESLTDEE 141 I + DFLA K KE L F+ FD D GKIS + LKR+ +++ L D+ Sbjct: 110 IHYTDFLAATIDKQTYL-KKEVCLIPFKFFDIDGNGKISVEELKRIFGRDDIENPLIDKA 168 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKK 168 + ++ E D +GDGE++ EF+ +M K Sbjct: 169 IDSLLQEVDLNGDGEIDFHEFMLMMSK 195 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 24/73 (32%), Positives = 41/73 (56%), Gaps = 8/73 (10%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE----PRKEE-MKKMISEVDKEATGK 83 +K+ F FD DG+G I V+ELK R G + P ++ + ++ EVD G+ Sbjct: 127 KKEVCLIPFKFFDIDGNGKISVEELK---RIFGRDDIENPLIDKAIDSLLQEVDLNGDGE 183 Query: 84 ISFNDFLAVMTQK 96 I F++F+ +M++K Sbjct: 184 IDFHEFMLMMSKK 196 >2LAP-A nrPDB Length = 167 Score = 81.6 bits (200), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 47/149 (31%), Positives = 87/149 (58%), Gaps = 5/149 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L ++ +E+REAF FD D G I+ ++L MR +G+ P + E+ ++ +++ G + Sbjct: 19 LRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHV 78 Query: 85 SFNDFLAVMTQKM----AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE-LGESLTD 139 F+DF+ +M K+ A+ +E+ AFR FD + G+IS L+ + LG + Sbjct: 79 DFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGH 138 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKK 168 +++E+I + D +GDG V+ EEF+++M + Sbjct: 139 RDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 >3J04-B nrPDB Length = 143 Score = 81.3 bits (199), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 49/142 (34%), Positives = 79/142 (55%), Gaps = 4/142 (2%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 + Q QE +EAF++ D + G ID ++L + ++G P E ++ M+SE A G I+F Sbjct: 3 QSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSE----APGPINF 58 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 FL + +K+ D ++ I AF FD++ +G I +L+ + +G+ TDEE+ EM Sbjct: 59 TMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDEMY 118 Query: 147 DEADRDGDGEVNEEEFLKIMKK 168 EA D G N EF +I+K Sbjct: 119 REAPIDKKGNFNYVEFTRILKH 140 >2JNF-A nrPDB Length = 158 Score = 80.5 bits (197), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 48/153 (31%), Positives = 87/153 (56%), Gaps = 5/153 (3%) Query: 19 VGPKPELTEDQKQEVREAFDLFDS-DGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD 77 +G +L+ +Q + + AF F++ +GSG + ++ + + LG + K ++++I E D Sbjct: 1 MGDVSKLSSNQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFD 60 Query: 78 KEATGKISFNDFLAVMTQKMAEK----DTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 G I F+ F + + + E+ ++E+ +AFRL+D + G IS ++ + EL Sbjct: 61 PFGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAEL 120 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 E+L+ E+L MIDE D DG G V+ EEF+ +M Sbjct: 121 DETLSSEDLDAMIDEIDADGSGTVDFEEFMGVM 153 Score = 49.7 bits (117), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 40/68 (58%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 E +QE+REAF L+D +G+G I ++ + L E++ MI E+D + +G + F Sbjct: 87 EQMQQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDF 146 Query: 87 NDFLAVMT 94 +F+ VMT Sbjct: 147 EEFMGVMT 154 >1W7I-B nrPDB Length = 151 Score = 78.6 bits (192), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 53/146 (36%), Positives = 81/146 (55%), Gaps = 7/146 (4%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMIS--EVDKEAT 81 E +DQ +E +EAF+LFD G G I + MRALG P E+ K++ + D+ + Sbjct: 3 EFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELKS 62 Query: 82 GKISFNDFLAVMTQKMAE---KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLT 138 ++ F FL M Q +A+ + T E+ L+ FR+FD + GK+ L+ V LGE +T Sbjct: 63 RRVDFETFLP-MLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMT 121 Query: 139 DEELQEMIDEADRDGDGEVNEEEFLK 164 +EE+ E + D +G +N E FLK Sbjct: 122 EEEV-ETVLAGHEDSNGCINYEAFLK 146 >1S6I-A nrPDB Length = 188 Score = 78.2 bits (191), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 45/144 (31%), Positives = 84/144 (58%), Gaps = 3/144 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E++ ++E F + D+D SGTI ELK ++ +G E + E+K ++ D + +G I Sbjct: 4 LSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTI 63 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 + +F+A T + + + +E ++ AF FD D +G I+ +++ + G L D + + Sbjct: 64 DYGEFIAA-TVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFG--LDDIHIDD 120 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 MI E D+D DG+++ EF +M+K Sbjct: 121 MIKEIDQDNDGQIDYGEFAAMMRK 144 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 46/87 (52%), Gaps = 3/87 (3%) Query: 11 ASTSYKRKVGPKPELTEDQKQE-VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEM 69 + Y + L + +++E + AF FD DGSG I + E++ A + G + + Sbjct: 61 GTIDYGEFIAATVHLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFGLDDI--HI 118 Query: 70 KKMISEVDKEATGKISFNDFLAVMTQK 96 MI E+D++ G+I + +F A+M ++ Sbjct: 119 DDMIKEIDQDNDGQIDYGEFAAMMRKR 145 >3DTP-E nrPDB Length = 196 Score = 76.6 bits (187), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 47/144 (32%), Positives = 80/144 (55%), Gaps = 5/144 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 T+ Q QE +EAF L D D G I +++ +LG ++E+ M++E A G I Sbjct: 51 FTQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMVAE----APGPI 106 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +F FL + ++A D ++ I+ AF LFD+ + GK + LKR GE + +E+ + Sbjct: 107 NFTMFLTIFGDRIAGTDEEDVIVNAFNLFDEGD-GKCKEETLKRSLTTWGEKFSQDEVDQ 165 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 + EA DG+G ++ ++F +I+ K Sbjct: 166 ALSEAPIDGNGLIDIKKFAQILTK 189 Score = 35.4 bits (80), Expect = 0.011, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 41/82 (50%), Gaps = 9/82 (10%) Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 S ++ A+ TQ + E +AF+L D D+ G IS +++ + LG T++EL Sbjct: 43 SGSNVFAMFTQHQVQ-----EFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDS 97 Query: 145 MIDEADRDGDGEVNEEEFLKIM 166 M+ EA G +N FL I Sbjct: 98 MVAEA----PGPINFTMFLTIF 115 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 19/72 (26%), Positives = 37/72 (51%), Gaps = 1/72 (1%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D++ + AF+LFD +G G + LK ++ G + ++E+ + +SE + G I Sbjct: 123 DEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTWGEKFSQDEVDQALSEAPIDGNGLIDIK 181 Query: 88 DFLAVMTQKMAE 99 F ++T+ E Sbjct: 182 KFAQILTKGAKE 193 >2RO9-A nrPDB Length = 69 Score = 76.6 bits (187), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 38/66 (57%), Positives = 50/66 (75%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D++EE+ +AFR+FD D+ G IS L+ V LGE LTDEE+ EMI EAD DGDG++N E Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 161 EFLKIM 166 EF+K+M Sbjct: 61 EFVKVM 66 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 43/69 (62%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+ +MI E D + G+I++ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 88 DFLAVMTQK 96 +F+ VM K Sbjct: 61 EFVKVMMAK 69 Score = 29.6 bits (65), Expect = 0.70, Method: Compositional matrix adjust. Identities = 22/64 (34%), Positives = 35/64 (54%), Gaps = 1/64 (1%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 +EE+K+ DK+ G IS + VMT + EK T EE+ + R D D G+I+++ Sbjct: 3 EEELKEAFRVFDKDQNGFISAAELRHVMTN-LGEKLTDEEVDEMIREADVDGDGQINYEE 61 Query: 126 LKRV 129 +V Sbjct: 62 FVKV 65 >2I08-A nrPDB Length = 78 Score = 76.6 bits (187), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 36/74 (48%), Positives = 49/74 (66%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF L+D DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 QLTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKM 97 I F +FL +M + M Sbjct: 63 IDFPEFLTMMARIM 76 Score = 53.5 bits (127), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 28/65 (43%), Positives = 40/65 (61%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +AF L+D D G I+ K L V LG + T+ ELQ+MI+E D DG+G ++ EFL +M Sbjct: 14 EAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFLTMMA 73 Query: 168 KTNLY 172 + Y Sbjct: 74 RIMKY 78 >2M29-A nrPDB Length = 171 Score = 76.3 bits (186), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 47/136 (34%), Positives = 76/136 (55%), Gaps = 5/136 (3%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 AF+ FD+D G I +EL MR LG+ P + E+ ++ V G + F +F+ +++ Sbjct: 33 AFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELISP 92 Query: 96 KMAEKDTK----EEILKAFRLFDDDETGKISFKNLKRVANE-LGESLTDEELQEMIDEAD 150 K+ E+ E+ AFR FD D G+I+ L++ A LGE L EL EM+ E D Sbjct: 93 KLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREMD 152 Query: 151 RDGDGEVNEEEFLKIM 166 +GDG ++ +EF+ ++ Sbjct: 153 LNGDGTIDFDEFVMML 168 >1FW4-A nrPDB Length = 71 Score = 75.9 bits (185), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 39/66 (59%), Positives = 49/66 (74%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ EMI EAD DGDG+VN E Sbjct: 3 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 62 Query: 161 EFLKIM 166 EF+++M Sbjct: 63 EFVQMM 68 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 28/69 (40%), Positives = 45/69 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 3 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 62 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 63 EFVQMMTAK 71 >2M5E-A nrPDB Length = 73 Score = 75.9 bits (185), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 37/70 (52%), Positives = 52/70 (74%) Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 M E+D++EE+++AF++FD D G IS L+ V LGE LTD+E+ EMI EAD DGDG Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGH 60 Query: 157 VNEEEFLKIM 166 +N EEF+++M Sbjct: 61 INYEEFVRMM 70 Score = 51.6 bits (122), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 26/70 (37%), Positives = 43/70 (61%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D ++E+ EAF +FD DG+G I EL+ M LG + +E+ +MI E D + G I++ Sbjct: 4 QDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINY 63 Query: 87 NDFLAVMTQK 96 +F+ +M K Sbjct: 64 EEFVRMMVSK 73 >2RO8-A nrPDB Length = 79 Score = 75.5 bits (184), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 39/79 (49%), Positives = 52/79 (65%), Gaps = 2/79 (2%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LT++Q E +EAF LFD DG G I KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 QLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDT 102 I F +FL +M +KM KDT Sbjct: 63 IDFPEFLNLMARKM--KDT 79 Score = 55.8 bits (133), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 29/64 (45%), Positives = 41/64 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 11 EFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLN 70 Query: 165 IMKK 168 +M + Sbjct: 71 LMAR 74 >2KN2-A nrPDB Length = 92 Score = 75.1 bits (183), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 37/66 (56%), Positives = 50/66 (75%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D +EE+ +AF++FD D+ G IS L+ V LGE LTDEE+++MI EAD DGDG+VN E Sbjct: 6 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 65 Query: 161 EFLKIM 166 EF+K+M Sbjct: 66 EFVKMM 71 Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 43/66 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+++MI E D + G++++ Sbjct: 6 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 65 Query: 88 DFLAVM 93 +F+ +M Sbjct: 66 EFVKMM 71 >2ROB-A nrPDB Length = 70 Score = 74.7 bits (182), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 37/66 (56%), Positives = 50/66 (75%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D +EE+ +AF++FD D+ G IS L+ V LGE LTDEE+++MI EAD DGDG+VN E Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 161 EFLKIM 166 EF+K+M Sbjct: 61 EFVKMM 66 Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 43/66 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+++MI E D + G++++ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 88 DFLAVM 93 +F+ +M Sbjct: 61 EFVKMM 66 >2OS8-B nrPDB Length = 157 Score = 73.6 bits (179), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 46/154 (29%), Positives = 88/154 (57%), Gaps = 5/154 (3%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE 75 K G +L + Q QE++EAF + D + G ID+ +LK +LG P +E+ M+ Sbjct: 4 KAASGVLTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML-- 61 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 KEA G ++F FL++ + K++ D++E I AF +FD+ +T K++ + +K + +G+ Sbjct: 62 --KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGD 119 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 + +E++ EA +G G+ + F+ ++K + Sbjct: 120 NFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIKGS 152 >2EC6-B nrPDB Length = 133 Score = 73.2 bits (178), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 43/137 (31%), Positives = 81/137 (59%), Gaps = 5/137 (3%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 QE++EAF + D + G ID+ +LK +LG P +E+ M+ KEA G ++F FL Sbjct: 2 QEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAML----KEAPGPLNFTMFL 57 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 ++ + K++ D++E I AF +FD+D T K++ + +K + +G++ +E++ EA Sbjct: 58 SIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMRMTFKEAP 117 Query: 151 RDGDGEVNEEEFLKIMK 167 +G G+ + F+ ++K Sbjct: 118 VEG-GKFDYVRFVAMIK 133 Score = 32.3 bits (72), Expect = 0.099, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 36/66 (54%), Gaps = 1/66 (1%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++ +R AF +FD D + ++++ +K + +G K+EM+ E E GK + Sbjct: 68 DSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMRMTFKEAPVEG-GKFDYV 126 Query: 88 DFLAVM 93 F+A++ Sbjct: 127 RFVAMI 132 >2KZ2-A nrPDB Length = 94 Score = 73.2 bits (178), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 39/70 (55%), Positives = 50/70 (71%) Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 M + D++EEI +AFR+ D D G IS L+ V LGE LTDEE+ EMI EAD DGDG+ Sbjct: 22 MKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQ 81 Query: 157 VNEEEFLKIM 166 VN EEF+++M Sbjct: 82 VNYEEFVQMM 91 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 44/69 (63%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF + D DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 26 DSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 85 Query: 88 DFLAVMTQK 96 +F+ +MT K Sbjct: 86 EFVQMMTAK 94 >2BL0-C nrPDB Length = 142 Score = 72.8 bits (177), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 74/140 (52%), Gaps = 1/140 (0%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +DQ E +EAF+LFDS+ +G I + L+ ++ G +M +E D GKI F Sbjct: 2 DDQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQF 61 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 +FL++M ++M + +++ + +AFR FD + TG I L+ LG+ L E E + Sbjct: 62 PEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPHEFAEFL 121 Query: 147 DEADRDGDGEVNEEEFLKIM 166 + + G++ + F+ M Sbjct: 122 GITETE-KGQIRYDNFINTM 140 >2AAO-A nrPDB Length = 166 Score = 72.8 bits (177), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 40/147 (27%), Positives = 86/147 (58%), Gaps = 3/147 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E++ ++E F++ D+D SG I +ELK ++ +G ++ E+ ++ D + +G I Sbjct: 21 LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTI 80 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 + +F+A T + + + ++ + AF FD D +G I+ L++ E G + D ++E Sbjct: 81 DYKEFIAA-TLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFG--VEDVRIEE 137 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKTNL 171 ++ + D+D DG ++ EF+ +M+K ++ Sbjct: 138 LMRDVDQDNDGRIDYNEFVAMMQKGSI 164 >5COC-A nrPDB Length = 130 Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 34/66 (51%), Positives = 44/66 (66%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLA 91 E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I F +FL Sbjct: 64 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 123 Query: 92 VMTQKM 97 +M +KM Sbjct: 124 MMARKM 129 Score = 56.2 bits (134), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 30/73 (41%), Positives = 45/73 (61%) Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDG 155 + A ++ E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G Sbjct: 55 QAAAEECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNG 114 Query: 156 EVNEEEFLKIMKK 168 ++ EFL +M + Sbjct: 115 TIDFPEFLTMMAR 127 >1TNP-A nrPDB Length = 90 Score = 72.4 bits (176), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 35/75 (46%), Positives = 49/75 (65%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+ E + AFD+FD+DG G I KEL MR LG P KEE+ +I EVD++ +G I Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 73 Query: 85 SFNDFLAVMTQKMAE 99 F +FL +M ++M E Sbjct: 74 DFEEFLVMMVRQMKE 88 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 28/60 (46%), Positives = 37/60 (61%) Query: 109 AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 AF +FD D G IS K L V LG++ T EEL +I+E D DG G ++ EEFL +M + Sbjct: 25 AFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVR 84 >1TRF-A nrPDB Length = 76 Score = 71.6 bits (174), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 34/73 (46%), Positives = 48/73 (65%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+ E + AFD+FD+DG G I KEL MR LG P KEE+ +I EVD++ +G I Sbjct: 3 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 62 Query: 85 SFNDFLAVMTQKM 97 F +FL +M ++M Sbjct: 63 DFEEFLVMMVRQM 75 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 28/60 (46%), Positives = 37/60 (61%) Query: 109 AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 AF +FD D G IS K L V LG++ T EEL +I+E D DG G ++ EEFL +M + Sbjct: 14 AFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDFEEFLVMMVR 73 >2KSZ-A nrPDB Length = 76 Score = 71.2 bits (173), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 34/73 (46%), Positives = 51/73 (69%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+Q + +EAF LFD DG G I V+EL +R+L P +EE++ MISEVD + G I Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 85 SFNDFLAVMTQKM 97 F++FL++M +K+ Sbjct: 64 EFDEFLSLMAKKV 76 Score = 52.8 bits (125), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 28/61 (45%), Positives = 39/61 (63%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +AF LFD D G I+ + L V L ++ T+EELQ+MI E D DG+G + +EFL +M Sbjct: 14 EAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLSLMA 73 Query: 168 K 168 K Sbjct: 74 K 74 >3TS5-B nrPDB Length = 161 Score = 70.9 bits (172), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 43/145 (29%), Positives = 84/145 (57%), Gaps = 5/145 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L + QE++EAF + D + G ID+ +LK +LG P +E+ M+ KEA G + Sbjct: 17 LPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML----KEAPGPL 72 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +F FL++ + K++ D++E I AF +FD+ +T K++ + +K + +G++ +E++ Sbjct: 73 NFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGDNFNKDEMRM 132 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKT 169 EA +G G+ + F+ ++K + Sbjct: 133 TFKEAPVEG-GKFDYVRFVAMIKGS 156 >5H53-C nrPDB Length = 153 Score = 70.1 bits (170), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 46/147 (31%), Positives = 77/147 (52%), Gaps = 5/147 (3%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 K E +++Q+ E +EAF L+D G I + ++ +RALG P E+KK++ E Sbjct: 2 KIEFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEM 61 Query: 82 G--KISFNDFLAVMTQKMAEKD--TKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 KI F FL ++ KD T E+ ++ R+FD + G + L+ V LGE + Sbjct: 62 NAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKM 121 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLK 164 +EE++ ++ D +G +N E F+K Sbjct: 122 KEEEVEALM-AGQEDSNGCINYEAFVK 147 >1DFK-Y nrPDB Length = 139 Score = 70.1 bits (170), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 43/143 (30%), Positives = 82/143 (57%), Gaps = 5/143 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L + Q QE++EAF + D D G + +++K LG P +E+ M+ KEA G + Sbjct: 1 LPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML----KEAPGPL 56 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +F FL++ + K++ D++E I AF +FD+ ET K++ + +K + +G++ +E++ Sbjct: 57 NFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKDEMRM 116 Query: 145 MIDEADRDGDGEVNEEEFLKIMK 167 EA +G G+ + +F ++K Sbjct: 117 TFKEAPVEG-GKFDYVKFTAMIK 138 >5H7D-E nrPDB Length = 120 Score = 70.1 bits (170), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 33/68 (48%), Positives = 44/68 (64%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 +Q Q +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I F Sbjct: 53 NQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 112 Query: 88 DFLAVMTQ 95 +FL +M + Sbjct: 113 EFLTMMAR 120 Score = 56.6 bits (135), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 28/60 (46%), Positives = 39/60 (65%) Query: 109 AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL +M + Sbjct: 61 AFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLTMMAR 120 >1B7T-Y nrPDB Length = 156 Score = 70.1 bits (170), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 45/155 (29%), Positives = 86/155 (55%), Gaps = 5/155 (3%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE 75 K G +L + Q QE++EAF + D D G + +++K LG P +E+ M+ Sbjct: 3 KAASGVLTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-- 60 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 KEA G ++F FL++ + K++ D++E I AF +FD+ ET K++ + +K + +G+ Sbjct: 61 --KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGD 118 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 + +E++ EA +G G+ + +F ++K + Sbjct: 119 NFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIKGSG 152 >2BL0-B nrPDB Length = 145 Score = 69.7 bits (169), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 40/139 (28%), Positives = 75/139 (53%), Gaps = 10/139 (7%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKE----ATGKISFN 87 +++E F +FD D G + ++EL A+R+LG P E+ + +++ + AT K + Sbjct: 6 QIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNAKEFDLATFKTVYR 65 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 + T++ +E+L AFR D + G I L+++ LG++LT E++E++ Sbjct: 66 KPIKTPTEQ------SKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEELMK 119 Query: 148 EADRDGDGEVNEEEFLKIM 166 E GDG +N E F+ ++ Sbjct: 120 EVSVSGDGAINYESFVDML 138 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 42/82 (51%), Gaps = 4/82 (4%) Query: 13 TSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKM 72 T Y++ + E Q +E+ +AF D +G+GTI EL+ + LG E++++ Sbjct: 62 TVYRKPIKTPTE----QSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEEL 117 Query: 73 ISEVDKEATGKISFNDFLAVMT 94 + EV G I++ F+ ++ Sbjct: 118 MKEVSVSGDGAINYESFVDMLV 139 Score = 32.7 bits (73), Expect = 0.090, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 8/61 (13%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 + ++I + F++FD D GK+S + L LG++ T+ EL + G++N +E Sbjct: 3 SADQIQECFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTI--------KGQLNAKE 54 Query: 162 F 162 F Sbjct: 55 F 55 >1F55-A nrPDB Length = 77 Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 30/73 (41%), Positives = 50/73 (68%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + +I Sbjct: 4 LTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQI 63 Query: 85 SFNDFLAVMTQKM 97 F++FLA+M++++ Sbjct: 64 EFSEFLALMSRQL 76 Score = 46.2 bits (108), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 23/61 (37%), Positives = 36/61 (59%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +AF LFD D G IS L V LG S ++ E+ ++++E D DG+ ++ EFL +M Sbjct: 14 EAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLALMS 73 Query: 168 K 168 + Sbjct: 74 R 74 >3JAX-C nrPDB Length = 151 Score = 68.9 bits (167), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 44/147 (29%), Positives = 77/147 (52%), Gaps = 5/147 (3%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMIS--EVDKEAT 81 + +E+Q E +EAF LFD G G I + MRALG P E+ K++ + D+ Sbjct: 3 DFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNL 62 Query: 82 GKISFNDFLAVMTQKMAEKDTK--EEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 + F FL +M KD E+ ++ R+FD + G + ++ V LGE +T+ Sbjct: 63 KTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTE 122 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIM 166 EE+++++ D +G +N EE ++++ Sbjct: 123 EEVEQLV-AGHEDSNGCINYEELVRMV 148 >1SR6-C nrPDB Length = 156 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 6/147 (4%) Query: 23 PELTEDQKQEVREAFDLFD-SDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 P+L++D+ ++++ F+LFD DG G +D +L R LG PR E++ + K Sbjct: 1 PKLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFA-VGGTHKMG 59 Query: 81 TGKISFNDFLAVMTQKM-AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 + F +FL M E+ T + ++AF+ FD + G IS L+ V LGE L+D Sbjct: 60 EKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSD 119 Query: 140 EELQEMIDEAD--RDGDGEVNEEEFLK 164 E++ E+I D D +G V E+F+K Sbjct: 120 EDVDEIIKLTDLQEDLEGNVKYEDFVK 146 >3I5H-B nrPDB Length = 153 Score = 68.2 bits (165), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 39/125 (31%), Positives = 72/125 (57%), Gaps = 4/125 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L++ Q QE++EAF + D D G I +++LK +LG P +E+ M+ KE G++ Sbjct: 10 LSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAML----KECPGQL 65 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +F FL + +K++ D ++ + AF +FD+D G I LK + +G++ + EE++ Sbjct: 66 NFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGDNFSKEEIKN 125 Query: 145 MIDEA 149 + +A Sbjct: 126 VWKDA 130 >3JBH-C nrPDB Length = 156 Score = 67.4 bits (163), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 44/138 (31%), Positives = 75/138 (54%), Gaps = 3/138 (2%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 ++ RE F+++D +G G ID ++L +R+L +P +KK DK K++ +FL Sbjct: 10 EKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKN-GGSDKRGEKKLTLEEFL 68 Query: 91 AVMTQKMAEKD--TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDE 148 + +Q EK+ T E+ ++ +++D E G + L V LGE LTD E +E++ Sbjct: 69 PIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIECEEIMRV 128 Query: 149 ADRDGDGEVNEEEFLKIM 166 D D DG + E F+K + Sbjct: 129 CDEDDDGFLKYEPFVKTI 146 >4Q57-A nrPDB Length = 65 Score = 67.4 bits (163), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 32/62 (51%), Positives = 41/62 (66%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLA 91 E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I F +FL Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 62 Query: 92 VM 93 +M Sbjct: 63 MM 64 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 29/62 (46%), Positives = 40/62 (64%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 62 Query: 165 IM 166 +M Sbjct: 63 MM 64 >1GGW-A nrPDB Length = 140 Score = 66.6 bits (161), Expect = 5e-12, Method: Compositional matrix adjust. Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 ++AF LFD G+G I + +RA G P E I+E++ ++ FL V+ Sbjct: 8 KQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAE----ITEIESTLPAEVDMEQFLQVL 63 Query: 94 TQKMA--EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + EE +K F++FD D TG I L+ V LGE L++EE+ E++ Sbjct: 64 NRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGVPV 123 Query: 152 DGDGEVNEEEFLKIM 166 DG VN +F++++ Sbjct: 124 K-DGMVNYHDFVQMI 137 Score = 37.0 bits (84), Expect = 0.004, Method: Compositional matrix adjust. Identities = 19/64 (29%), Positives = 38/64 (59%), Gaps = 1/64 (1%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 +E + F +FD D +G I V EL+ + +LG + EEM +++ V + G ++++DF Sbjct: 75 PEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGVPVK-DGMVNYHDF 133 Query: 90 LAVM 93 + ++ Sbjct: 134 VQMI 137 >5B7X-A nrPDB Length = 156 Score = 66.2 bits (160), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 41/137 (29%), Positives = 76/137 (55%), Gaps = 2/137 (1%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 Q++R+ F+ +D D G IDVK+L +R+LG P ++E+ I E E F Sbjct: 13 QKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAIEGE-TFQIEQFE 71 Query: 91 AVMTQKMAEKDTKE-EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 +M ++ ++ DT+E ++ KAF +FD D+ GKI +L +G+ +T EE++++ Sbjct: 72 LIMEREQSKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTTVGDKMTKEEVEKVFSIL 131 Query: 150 DRDGDGEVNEEEFLKIM 166 + +++ FLK++ Sbjct: 132 GITMESDIDLATFLKLV 148 >5VLN-A nrPDB Length = 120 Score = 65.5 bits (158), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 40/107 (37%), Positives = 57/107 (53%), Gaps = 17/107 (15%) Query: 24 ELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 +LTE+QK E + AFD+F G+I KEL MR LG P EE+++MI EVD++ +G Sbjct: 11 QLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSG 70 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + F++FL +M + M DD GK L+RV Sbjct: 71 TVDFDEFLVMMVRSMK----------------DDSKGKFKRPTLRRV 101 Score = 53.5 bits (127), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 33/68 (48%), Positives = 42/68 (61%), Gaps = 1/68 (1%) Query: 103 KEEILKAFRLFD-DDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 K E AF +F E G IS K L +V LG++ T EELQEMIDE D DG G V+ +E Sbjct: 17 KNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDE 76 Query: 162 FLKIMKKT 169 FL +M ++ Sbjct: 77 FLVMMVRS 84 >4GJF-A nrPDB Length = 89 Score = 64.7 bits (156), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 33/75 (44%), Positives = 48/75 (64%), Gaps = 1/75 (1%) Query: 24 ELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 +LTE+QK E + AFD+F G I KEL MR LG P EE+++MI EVD++ +G Sbjct: 11 QLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSG 70 Query: 83 KISFNDFLAVMTQKM 97 + F++FL +M + M Sbjct: 71 TVDFDEFLVMMVRCM 85 Score = 53.1 bits (126), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 33/68 (48%), Positives = 41/68 (60%), Gaps = 1/68 (1%) Query: 103 KEEILKAFRLF-DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 K E AF +F E G IS K L +V LG++ T EELQEMIDE D DG G V+ +E Sbjct: 17 KNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVDFDE 76 Query: 162 FLKIMKKT 169 FL +M + Sbjct: 77 FLVMMVRC 84 >2N7L-C nrPDB Length = 141 Score = 64.3 bits (155), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 36/84 (42%), Positives = 53/84 (63%), Gaps = 3/84 (3%) Query: 24 ELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 +LTE+QK E + AFD+F G+I KEL MR LG P EE+++MI EVD++ +G Sbjct: 26 QLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSG 85 Query: 83 KISFNDFLAVMTQKMAEKDTKEEI 106 + F++FL +M + M KD E + Sbjct: 86 TVDFDEFLVMMVRXM--KDDSENL 107 Score = 54.3 bits (129), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 8/95 (8%) Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFD-DDETGKISFKNLKRVANELGESLTDEELQ 143 S +D +++ E + K E AF +F E G IS K L +V LG++ T EELQ Sbjct: 15 SMDDIYKAAVEQLTE-EQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQ 73 Query: 144 EMIDEADRDGDGEVNEEEFLKIMKKT------NLY 172 EMIDE D DG G V+ +EFL +M + NLY Sbjct: 74 EMIDEVDEDGSGTVDFDEFLVMMVRXMKDDSENLY 108 >1N2D-A nrPDB Length = 148 Score = 64.3 bits (155), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 44/143 (30%), Positives = 75/143 (52%), Gaps = 20/143 (13%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMI----------SEVDKEATGK 83 ++ F LFD G G I L +RA+G+ P + ++ +I S + TG Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGL 66 Query: 84 ISFNDFLAVMTQKMAEKDTK---EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDE 140 I N +K + TK E+ +KAF++FD + TGK+S +L+ + LGE LTD Sbjct: 67 IEVN-------EKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDA 119 Query: 141 ELQEMIDEADRDGDGEVNEEEFL 163 E+ E++ + D +GE++ ++F+ Sbjct: 120 EVDELLKGVEVDSNGEIDYKKFI 142 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 15/65 (23%), Positives = 38/65 (58%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 T+ + ++ +AF +FD + +G + V +L+ + LG + E+ +++ V+ ++ G+I Sbjct: 78 TKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEID 137 Query: 86 FNDFL 90 + F+ Sbjct: 138 YKKFI 142 >2W4G-C nrPDB Length = 145 Score = 63.9 bits (154), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 46/141 (32%), Positives = 77/141 (54%), Gaps = 5/141 (3%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG--KIS 85 D+ + +EAF LFD G I + ++ +RALG P E+ K++ KE KI+ Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKIT 60 Query: 86 FNDFLAVMTQKMAEKD--TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 F +FL ++ KD T E+ ++ R+FD + G + L+ V LGE +T+EE++ Sbjct: 61 FEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVE 120 Query: 144 EMIDEADRDGDGEVNEEEFLK 164 E++ + D +G +N E F+K Sbjct: 121 ELM-KGQEDSNGCINYEAFVK 140 >2HF5-A nrPDB Length = 68 Score = 63.5 bits (153), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 31/67 (46%), Positives = 44/67 (65%) Query: 68 EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLK 127 E++ MI+EVD + G I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELR 61 Query: 128 RVANELG 134 V LG Sbjct: 62 HVMTNLG 68 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 17/34 (50%), Positives = 23/34 (67%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG 61 D ++E+REAF +FD DG+G I EL+ M LG Sbjct: 35 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 68 Score = 33.1 bits (74), Expect = 0.057, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 21/28 (75%) Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKK 168 ELQ+MI+E D DG+G ++ EFL +M + Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMAR 29 >2LV7-A nrPDB Length = 100 Score = 63.2 bits (152), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 27/70 (38%), Positives = 49/70 (70%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ++ ED+ +E+REAF +FD DG+G I +EL AMR+LG+ P + E++ +I +D + G+ Sbjct: 29 DIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQ 88 Query: 84 ISFNDFLAVM 93 + F +F+ ++ Sbjct: 89 VDFEEFVTLL 98 Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 27/67 (40%), Positives = 40/67 (59%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 +D EEI +AF++FD D G IS + L LG + EL+ +I D DGDG+V+ Sbjct: 32 EDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQVDF 91 Query: 160 EEFLKIM 166 EEF+ ++ Sbjct: 92 EEFVTLL 98 >5TBY-E nrPDB Length = 166 Score = 62.8 bits (151), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 43/141 (30%), Positives = 72/141 (51%), Gaps = 5/141 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKIS 85 + Q QE +EAF + D + G ID +L+ ALG + EE+ +MI KEA G I+ Sbjct: 23 QTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMI----KEAPGPIN 78 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F FL + +K+ D +E IL AF++FD + G + ++ + E + EE+ +M Sbjct: 79 FTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQM 138 Query: 146 IDEADRDGDGEVNEEEFLKIM 166 D G ++ + + I+ Sbjct: 139 FAAFPPDVTGNLDYKNLVHII 159 Score = 31.2 bits (69), Expect = 0.22, Method: Compositional matrix adjust. Identities = 14/68 (20%), Positives = 33/68 (48%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++ + AF +FD +G G + ++ + KEE+ +M + + TG + + Sbjct: 94 DPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERFSKEEVDQMFAAFPPDVTGNLDYK 153 Query: 88 DFLAVMTQ 95 + + ++T Sbjct: 154 NLVHIITH 161 >3HZT-A nrPDB Length = 467 Score = 61.6 bits (148), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 45/154 (29%), Positives = 81/154 (52%), Gaps = 14/154 (9%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL-----------GFEPRKEEMKKMIS 74 T ++ +E+ + F D++G G +D KEL R L + E+ ++ Sbjct: 309 TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEAEVDHILQ 368 Query: 75 EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG 134 VD + G I +++F+ V K ++E +L AF+ FD D +GKI+ + L R+ Sbjct: 369 SVDFDRNGYIEYSEFVTVCMDKQLLL-SRERLLAAFQQFDSDGSGKITNEELGRLFGV-- 425 Query: 135 ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + DE +++ E D++ DGEV+ EEF+++M+K Sbjct: 426 TEVDDETWHQVLQECDKNNDGEVDFEEFVEMMQK 459 >6FSA-D nrPDB Length = 199 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 7/149 (4%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVA--MRALGFEPRKEEMKKMISEVDKE 79 K E T +Q +E +EAF LFD + + + +RALG P + E+ +++ + +E Sbjct: 47 KIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQE 106 Query: 80 ATGK--ISFNDFLAVMTQKMAEKDTK--EEILKAFRLFDDDETGKISFKNLKRVANELGE 135 + F+ FL ++ KDT E+ ++ R+FD + G + L+ V LGE Sbjct: 107 ELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 166 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLK 164 LT++E+++++ D +G +N E F+K Sbjct: 167 KLTEDEVEKLM-AGQEDSNGCINYEAFVK 194 >2N8Y-A nrPDB Length = 153 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 32/109 (29%), Positives = 65/109 (59%), Gaps = 6/109 (5%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF----EPRKE-EMKKMISEVDKE 79 ++++Q E R +F+ FD D SGT+ +E K + +LG+ +P+ E E +++S VD Sbjct: 4 ISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPN 63 Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 G ++F F+ M+++ A+ DT ++++ +F++ D+ I+ L+R Sbjct: 64 RLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRR 111 >4ORC-B nrPDB Length = 170 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 87/150 (58%), Gaps = 9/150 (6%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D+ + + + F D D SG++ V+E +++ L P ++++I D + G++ F Sbjct: 18 DEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEVDFK 73 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMI 146 +F+ ++Q + D ++++ AFR++D D+ G IS L +V + G +L D +LQ+++ Sbjct: 74 EFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQLQQIV 133 Query: 147 DE----ADRDGDGEVNEEEFLKIMKKTNLY 172 D+ AD+DGDG ++ EEF ++ +++ Sbjct: 134 DKTIINADKDGDGRISFEEFCAVVGGLDIH 163 >4D1E-A nrPDB Length = 876 Score = 61.2 bits (147), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 25/92 (27%), Positives = 56/92 (60%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 +T++Q E R +F+ FD +G +D ++ + + ++G++ + E ++++ VD G + Sbjct: 732 ITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTV 791 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDD 116 +F F+ MT++ A+ DT E+++ +FR+ D Sbjct: 792 TFQSFIDFMTRETADTDTAEQVIASFRILASD 823 >4JWQ-A nrPDB Length = 199 Score = 60.8 bits (146), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 42/144 (29%), Positives = 81/144 (56%), Gaps = 12/144 (8%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-PRKEEMKKMISEVDKEATGKISFNDF 89 Q+++ F D DG G I +LK + G + P+ ++ ++ ++D + +G+I + +F Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLPQNFDV--LLDQIDSDGSGRIDYTEF 115 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV---ANELGESLTDEELQE-- 144 LA + + +K+ I AFR+FD D G+I+ L + N+ G S+T +++ + Sbjct: 116 LAAALDR--KHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKG-SITQKDVNQVK 172 Query: 145 -MIDEADRDGDGEVNEEEFLKIMK 167 MI E D++ DG+++ EF ++MK Sbjct: 173 KMIQEVDKNNDGKIDFYEFCEMMK 196 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/72 (37%), Positives = 37/72 (51%), Gaps = 5/72 (6%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAM---RALGFEPRKE--EMKKMISEVDKEATGKI 84 K+ + AF +FD D G I EL + G +K+ ++KKMI EVDK GKI Sbjct: 127 KKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDVNQVKKMIQEVDKNNDGKI 186 Query: 85 SFNDFLAVMTQK 96 F +F +M K Sbjct: 187 DFYEFCEMMKLK 198 Score = 29.6 bits (65), Expect = 0.79, Method: Compositional matrix adjust. Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 + ++ Q+ + D +++ F D+D G I+ LK+ G L + ++D+ Sbjct: 45 MTIIAQQSNDYDL-QQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKLP-QNFDVLLDQI 102 Query: 150 DRDGDGEVNEEEFL 163 D DG G ++ EFL Sbjct: 103 DSDGSGRIDYTEFL 116 >3KHE-A nrPDB Length = 191 Score = 60.8 bits (146), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 51/176 (28%), Positives = 90/176 (51%), Gaps = 17/176 (9%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL---- 60 F+ S + + +G K E+ K E+ + F D++G G +D KEL R L Sbjct: 15 FQSSQKLAQAAMLFMGSKLTTLEETK-ELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWK 73 Query: 61 -------GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLF 113 + E+ ++ VD + G I +++F+ V K ++E +L AF+ F Sbjct: 74 GDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMDKQLLL-SRERLLAAFQQF 132 Query: 114 DDDETGKISFKNLKRVANELGES-LTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 D D +GKI+ + L R+ G + + DE +++ E D++ DGEV+ EEF+++M+K Sbjct: 133 DSDGSGKITNEELGRL---FGVTEVDDETWHQVLQECDKNNDGEVDFEEFVEMMQK 185 >5TBY-C nrPDB Length = 195 Score = 60.8 bits (146), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 44/149 (29%), Positives = 78/149 (52%), Gaps = 7/149 (4%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVA--MRALGFEPRKEEMKKMISEVDKE 79 K E T +Q +E +EAF LFD + + + +RALG P + E+ +++ + +E Sbjct: 43 KIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPRQE 102 Query: 80 --ATGKISFNDFLAVMTQKMAEKDT--KEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 T + F FL ++ KDT E+ ++ R+FD + G + L+ V LGE Sbjct: 103 ELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 162 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLK 164 LT++E+++++ D +G +N E F+K Sbjct: 163 RLTEDEVEKLM-AGQEDSNGCINYEAFVK 190 >1O1A-B nrPDB Length = 145 Score = 59.3 bits (142), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 5/141 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKIS 85 E + ++ +EAF + D + G ID +L+ A+G + EE+ MI KEA+G I+ Sbjct: 3 ETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI----KEASGPIN 58 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F FL + +K+ D ++ I+ AF++ D D G I L+ + G T EE++ M Sbjct: 59 FTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIKNM 118 Query: 146 IDEADRDGDGEVNEEEFLKIM 166 D G V+ + ++ Sbjct: 119 WAAFPPDVAGNVDYKNICYVI 139 Score = 30.8 bits (68), Expect = 0.32, Method: Compositional matrix adjust. Identities = 17/68 (25%), Positives = 30/68 (44%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + + AF + D DG G+I L+ + G EE+K M + + G + + Sbjct: 74 DPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIKNMWAAFPPDVAGNVDYK 133 Query: 88 DFLAVMTQ 95 + V+T Sbjct: 134 NICYVITH 141 >1I84-U nrPDB Length = 166 Score = 59.3 bits (142), Expect = 9e-10, Method: Compositional matrix adjust. Identities = 41/141 (29%), Positives = 70/141 (49%), Gaps = 5/141 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKIS 85 E + ++ +EAF + D + G ID +L+ A+G + EE+ MI KEA+G I+ Sbjct: 21 ETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI----KEASGPIN 76 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F FL + +K+ D ++ I+ AF++ D D G I L+ + G T EE++ M Sbjct: 77 FTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIKNM 136 Query: 146 IDEADRDGDGEVNEEEFLKIM 166 D G V+ + ++ Sbjct: 137 WAAFPPDVAGNVDYKNICYVI 157 Score = 30.8 bits (68), Expect = 0.34, Method: Compositional matrix adjust. Identities = 17/68 (25%), Positives = 30/68 (44%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + + AF + D DG G+I L+ + G EE+K M + + G + + Sbjct: 92 DPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIKNMWAAFPPDVAGNVDYK 151 Query: 88 DFLAVMTQ 95 + V+T Sbjct: 152 NICYVITH 159 >3NCG-A nrPDB Length = 486 Score = 58.9 bits (141), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 86/156 (55%), Gaps = 15/156 (9%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVA----MRALGFEPR----------KEEMKK 71 T D+ +++ E F D++ G +D EL MR G + ++++ Sbjct: 326 TLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFMRLKGVDSNSLIQNEGSTIEDQIDS 385 Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN 131 ++ +D + +G I +++F+A + ++E + +AF++FD D +GKIS K L ++ + Sbjct: 386 LMPLLDMDGSGSIEYSEFIASAIDRTILL-SRERMERAFKMFDKDGSGKISTKELFKLFS 444 Query: 132 ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + S+ EEL+ +I++ D + DGEV+ EF+++++ Sbjct: 445 QADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 >3Q5I-A nrPDB Length = 504 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 44/153 (28%), Positives = 85/153 (55%), Gaps = 13/153 (8%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG--------FEPRKEEMKKMISEVD 77 T ++++E+ + F D +G G +D KEL L + +EE+ ++ EVD Sbjct: 350 TLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFKNELGELKNVEEEVDNILKEVD 409 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG-ES 136 + G I +++F++V K ++E + +AF LFD D++GKI+ + L AN G S Sbjct: 410 FDKNGYIEYSEFISVCMDKQI-LFSEERLRRAFNLFDTDKSGKITKEEL---ANLFGLTS 465 Query: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 ++++ +++ EAD++ D ++ +EF+ +M K Sbjct: 466 ISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKI 498 >3I5I-C nrPDB Length = 159 Score = 58.2 bits (139), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 45/148 (30%), Positives = 78/148 (52%), Gaps = 9/148 (6%) Query: 24 ELTEDQKQEVREAFDLFD-SDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 +LT+D+ +EVRE FDLFD DG G +D ++ +R LG P + ++ + K Sbjct: 2 QLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQH-GGTKKMGE 60 Query: 82 GKISFNDFLAVMTQKMAEKDT---KEEILKAFRLFDDDETGKISFKNLKRVANELGESLT 138 + L + ++M+ KDT +E ++AF+ FD + G IS ++ V LGE +T Sbjct: 61 KAYKLEEILPIY-EEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGERIT 119 Query: 139 DEELQEMIDEAD--RDGDGEVNEEEFLK 164 +++ ++ D D DG + E+ +K Sbjct: 120 EDQCNDIFTFCDIREDIDGNIKYEDLMK 147 >2M8U-A nrPDB Length = 77 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 26/71 (36%), Positives = 45/71 (63%) Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDG 155 M +TK ++++AF++FD D G ++ L++V NELG+ + +E++EMI EAD G Sbjct: 3 HMNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSG 62 Query: 156 EVNEEEFLKIM 166 V E F+ ++ Sbjct: 63 YVQYETFVGML 73 Score = 44.3 bits (103), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 39/66 (59%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 + K +V EAF +FD DG+G + V L+ + LG +E+++MI E D + +G + + Sbjct: 8 NTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYE 67 Query: 88 DFLAVM 93 F+ ++ Sbjct: 68 TFVGML 73 >3H4S-E nrPDB Length = 135 Score = 57.4 bits (137), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 34/100 (34%), Positives = 54/100 (54%), Gaps = 1/100 (1%) Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 K M+ E + + D L VM +KM ++ E+ K F L D E I+ ++L+R Sbjct: 6 KSMLLETTSTTKMETKYEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAESLRRN 65 Query: 130 ANELG-ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + LG E ++ E+ Q M+ E D DGDG +N+ EF +M + Sbjct: 66 SGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVR 105 >3O4Y-A nrPDB Length = 196 Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 43/146 (29%), Positives = 81/146 (55%), Gaps = 12/146 (8%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-PRKEEMKKMISEVDKEATGKISFNDF 89 Q+++ AF D +G G I +L+ + G P ++ ++ ++D + +G I + +F Sbjct: 55 QKLKAAFLHLDEEGKGNITKLQLRKGLERSGLMLPPNFDL--LLDQIDSDGSGNIDYTEF 112 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV---ANELGESLTDEELQE-- 144 LA + + +K+ I AFR+FD D G+I+ L V N+ G ++T+ ++ + Sbjct: 113 LAAAIDR--RQLSKKLIYCAFRVFDVDNDGEITTAELAHVLFNGNKRG-NITERDVNQVK 169 Query: 145 -MIDEADRDGDGEVNEEEFLKIMKKT 169 MI E D++GDG+++ EF ++MK T Sbjct: 170 KMIREVDKNGDGKIDFYEFSEMMKLT 195 >2B1U-A nrPDB Length = 71 Score = 57.0 bits (136), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 30/65 (46%), Positives = 39/65 (60%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E++ AFR FD D G I+ L+R LG+ L EEL MI EAD D DG VN EEF Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFA 65 Query: 164 KIMKK 168 +++ + Sbjct: 66 RMLAQ 70 Score = 48.5 bits (114), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 24/61 (39%), Positives = 36/61 (59%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 AF FD DG G I V EL+ AM LG +EE+ MI E D + G++++ +F ++ Q Sbjct: 11 AFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFARMLAQ 70 Query: 96 K 96 + Sbjct: 71 E 71 >5B8I-B nrPDB Length = 171 Score = 56.6 bits (135), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 45/138 (32%), Positives = 79/138 (57%), Gaps = 11/138 (7%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 D D SGTI+ E +++ + P +MI+ D++ G + F +F++ ++ + Sbjct: 30 LDRDKSGTIERDEF-LSLPQVSSNPLS---TRMIAIFDEDGGGDVDFQEFVSGLS-AFSS 84 Query: 100 KDTKEEILK-AFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMID----EADRDG 153 K KEE L+ AF+++D D G IS L V + G +L D +LQ+++D EAD DG Sbjct: 85 KGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIVDKTIMEADLDG 144 Query: 154 DGEVNEEEFLKIMKKTNL 171 DG ++ EEF ++++ T++ Sbjct: 145 DGRISFEEFTRMVENTDV 162 >1C7W-A nrPDB Length = 81 Score = 56.2 bits (134), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 30/71 (42%), Positives = 49/71 (69%), Gaps = 1/71 (1%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE-SLTDEELQEMIDEADRDGDGEVN 158 +D +EEIL+AF++FD + G I F K + ++GE LTD E++E + EAD DG+G ++ Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVID 63 Query: 159 EEEFLKIMKKT 169 EF+ ++KK+ Sbjct: 64 IPEFMDLIKKS 74 Score = 43.5 bits (101), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 22/70 (31%), Positives = 43/70 (61%), Gaps = 1/70 (1%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE-EMKKMISEVDKEATGK 83 + +D ++E+ AF +FD++G G ID E K M+ +G EP + E+++ + E D++ G Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGV 61 Query: 84 ISFNDFLAVM 93 I +F+ ++ Sbjct: 62 IDIPEFMDLI 71 >1SJJ-A nrPDB Length = 863 Score = 56.2 bits (134), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 25/104 (24%), Positives = 61/104 (58%), Gaps = 1/104 (0%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 ++++Q E R +F+ FD +G +D ++ + + ++G+ + E +++S VD G + Sbjct: 719 ISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVV 778 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 +F F+ M+++ A+ DT ++++ +F++ D+ I+ L+R Sbjct: 779 TFQAFIDFMSRETADTDTADQVMASFKILAGDK-NYITVDELRR 821 >5JN2-A nrPDB Length = 525 Score = 55.5 bits (132), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 46/155 (29%), Positives = 81/155 (52%), Gaps = 16/155 (10%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKEL----KVAMRALGFEPR-------KEEMKKMIS 74 ++D+ +E+ F D +G G +D EL K MR G + + E+ +++ Sbjct: 371 SQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELMRMKGQDASMLDASAVEHEVDQVLD 430 Query: 75 EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG 134 VD + G I +++F+ V + ++E + +AFR+FD D +GKIS L A G Sbjct: 431 AVDFDKNGYIEYSEFVTVAMDRKTLL-SRERLERAFRMFDSDNSGKISSTEL---ATIFG 486 Query: 135 ESLTDEE-LQEMIDEADRDGDGEVNEEEFLKIMKK 168 S D E + ++ E D++ DGEV+ +EF +++ K Sbjct: 487 VSDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLK 521 >4RGJ-A nrPDB Length = 520 Score = 55.1 bits (131), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 46/164 (28%), Positives = 83/164 (50%), Gaps = 26/164 (15%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE------------EMKKMI 73 T D+ +E+ + F D +G G +D EL + + L + + E E+ +++ Sbjct: 366 TIDETKELTKIFKKMDKNGDGQLDRNELIIGYKEL-LKLKGEDTSDLDNAAIEYEVDQIL 424 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 + +D + G I +++FL V + T E + KAF+LFD D +GKIS ANEL Sbjct: 425 NSIDLDQNGYIEYSEFLTVSIDRKLLLST-ERLEKAFKLFDKDGSGKIS-------ANEL 476 Query: 134 GE-----SLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 + ++ E + ++ E D++ DGE++ +EF ++ K Y Sbjct: 477 AQLFGLSDVSSECWKTVLKEVDQNNDGEIDFKEFRDMLVKLCNY 520 >2K2A-A nrPDB Length = 70 Score = 54.7 bits (130), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 28/64 (43%), Positives = 43/64 (67%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 ++E+ +AFRL+D + G IS ++ + EL E+L+ E+L MIDE D DG G V+ EEF Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEF 61 Query: 163 LKIM 166 + +M Sbjct: 62 MGVM 65 Score = 49.3 bits (116), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 39/65 (60%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 +QE+REAF L+D +G+G I ++ + L E++ MI E+D + +G + F +F Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEF 61 Query: 90 LAVMT 94 + VMT Sbjct: 62 MGVMT 66 >5H53-B nrPDB Length = 146 Score = 53.9 bits (128), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 39/139 (28%), Positives = 70/139 (50%), Gaps = 5/139 (3%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKISFN 87 Q QE +EAF + D + G ID ++L+ A+G + EE+ M+ KEA+G I+F Sbjct: 3 QIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMM----KEASGPINFT 58 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 FL + +K+ D ++ I AF++ D + G I + L+ + + + EE++ M Sbjct: 59 VFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQCDRFSQEEIKNMWA 118 Query: 148 EADRDGDGEVNEEEFLKIM 166 D G V+ + ++ Sbjct: 119 AFSPDVGGNVDYKNICYVI 137 >3K21-A nrPDB Length = 191 Score = 53.1 bits (126), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 39/144 (27%), Positives = 82/144 (56%), Gaps = 12/144 (8%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-PRKEEMKKMISEVDKEATGKISFNDF 89 ++++ F + D DG G I ++LK + G + P ++ ++ ++D + +GKI + +F Sbjct: 52 EKLKSTFLVLDEDGKGYITKEQLKKGLEKDGLKLPYNFDL--LLDQIDSDGSGKIDYTEF 109 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV---ANELGESLTDEEL---Q 143 +A + ++ +K+ I AFR+FD D G+I+ L + N+ G ++T ++ + Sbjct: 110 IAAALDR--KQLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKG-NITQRDVNRVK 166 Query: 144 EMIDEADRDGDGEVNEEEFLKIMK 167 MI + D++ DG+++ EF ++MK Sbjct: 167 RMIRDVDKNNDGKIDFHEFSEMMK 190 >5E37-A nrPDB Length = 356 Score = 52.8 bits (125), Expect = 7e-08, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 74/151 (49%), Gaps = 11/151 (7%) Query: 31 QEVREAFDLFDSDGSGTIDVKELK----------VAMRALGFEPRKEEMKKMISEVDKEA 80 +E+ F + D DG+G ID +EL+ V M + + P ++E+++ + + D Sbjct: 29 EELERRFKMADVDGNGHIDREELRNLLESMESGEVYMMSQHWLP-EDELERCMEQYDVNK 87 Query: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDE 140 G ISF +F ++ + + T E AF+ D G I L ++ LG ++ E Sbjct: 88 DGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLE 147 Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 +L +++ D+D G++ EFL + + + L Sbjct: 148 KLVDLMQMYDKDDSGQIEFPEFLLMFRNSLL 178 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 32/66 (48%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L E E AF D G+GTI EL +LG E++ ++ DK+ +G+I Sbjct: 105 LLEGTLAEYESAFKAVDKSGNGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQI 164 Query: 85 SFNDFL 90 F +FL Sbjct: 165 EFPEFL 170 Score = 29.3 bits (64), Expect = 0.80, Method: Compositional matrix adjust. Identities = 24/100 (24%), Positives = 46/100 (46%), Gaps = 5/100 (5%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELK-VAMRALGFEPRKEEMKKMISEVDKEATGK 83 L ED+ + E +D+ + G I +E K + L E E + VDK G Sbjct: 71 LPEDELERCMEQYDV---NKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSGNGT 127 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 I + L+ + + + E+++ +++D D++G+I F Sbjct: 128 IGATE-LSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEF 166 >2K7B-A nrPDB Length = 76 Score = 52.0 bits (123), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 44/73 (60%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L ++ +E+REAF FD D G I+ ++L MR +G+ P + E+ ++ +++ G + Sbjct: 4 LRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHV 63 Query: 85 SFNDFLAVMTQKM 97 F+DF+ +M K+ Sbjct: 64 DFDDFVELMGPKL 76 Score = 35.8 bits (81), Expect = 0.011, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 38/63 (60%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 EE+ +AFR FD D+ G I+ ++L +G T+ EL E+ + + + G V+ ++F+ Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFV 69 Query: 164 KIM 166 ++M Sbjct: 70 ELM 72 >3LIJ-A nrPDB Length = 494 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 43/151 (28%), Positives = 78/151 (51%), Gaps = 11/151 (7%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-------PRKE-EMKKMISEVD 77 ++++ +E+ + F D +G G +D +EL L E P+ E E+ ++ D Sbjct: 341 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 400 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 + G I +++F+ V + + +K+++ AF+ FD D GKIS L V + L Sbjct: 401 FDRNGYIDYSEFVTVAMDRKSLL-SKDKLESAFQKFDQDGNGKISVDELASVFGL--DHL 457 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + +EMI D + DG+V+ EEF K+++K Sbjct: 458 ESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 488 >3L19-A nrPDB Length = 214 Score = 51.2 bits (121), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 43/151 (28%), Positives = 78/151 (51%), Gaps = 11/151 (7%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-------PRKE-EMKKMISEVD 77 ++++ +E+ + F D +G G +D +EL L E P+ E E+ ++ D Sbjct: 58 SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEEVAVFDLPQIESEVDAILGAAD 117 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 + G I +++F+ V + + +K+++ AF+ FD D GKIS L V + L Sbjct: 118 FDRNGYIDYSEFVTVAMDRKSLL-SKDKLESAFQKFDQDGNGKISVDELASVFGL--DHL 174 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + +EMI D + DG+V+ EEF K+++K Sbjct: 175 ESKTWKEMISGIDSNNDGDVDFEEFCKMIQK 205 >1Y1X-A nrPDB Length = 191 Score = 50.8 bits (120), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 35/139 (25%), Positives = 65/139 (46%), Gaps = 13/139 (9%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 QE+ E F D+DGSG I V EL A+ + G +K++ DK +G+I+F++F Sbjct: 26 NQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEITFDEF 85 Query: 90 LAVMTQKMAEKDTKEEILK---AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 KD IL FR D G++ ++ G ++++ Q ++ Sbjct: 86 ----------KDLHHFILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALM 135 Query: 147 DEADRDGDGEVNEEEFLKI 165 + DR G + ++++++ Sbjct: 136 RKFDRQRRGSLGFDDYVEL 154 >2FCE-A nrPDB Length = 70 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 23/60 (38%), Positives = 42/60 (70%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E+ +KAF++FD + TGK+S +L+ + LGE LTD E+ E++ + D +GE++ ++F+ Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 64 Score = 31.6 bits (70), Expect = 0.18, Method: Compositional matrix adjust. Identities = 14/55 (25%), Positives = 32/55 (58%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 AF +FD + +G + V +L+ + LG + E+ +++ V+ ++ G+I + F+ Sbjct: 10 AFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 64 Score = 30.0 bits (66), Expect = 0.54, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 31/61 (50%), Gaps = 1/61 (1%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + E+ K DKE+TGK+S D L M + EK T E+ + + + D G+I + Sbjct: 2 AKTEDFVKAFQVFDKESTGKVSVGD-LRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDY 60 Query: 124 K 124 K Sbjct: 61 K 61 >5W1A-B nrPDB Length = 155 Score = 50.4 bits (119), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 40/140 (28%), Positives = 68/140 (48%), Gaps = 6/140 (4%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 + V F++ S G G ID +L A+RAL P ++K+ K KI ++FL Sbjct: 10 ENVEFVFEVMGSPGEG-IDAVDLGDALRALNLNPTLALIEKL-GGTKKRNEKKIKLDEFL 67 Query: 91 AVMTQ--KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDE 148 + +Q K E+ E+ ++ +L+D +E G + L+ LGESL DE+++ + + Sbjct: 68 PIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFAD 127 Query: 149 A--DRDGDGEVNEEEFLKIM 166 D +G + FL M Sbjct: 128 CMDPEDDEGFIPYSPFLARM 147 Score = 30.0 bits (66), Expect = 0.59, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 36/64 (56%), Gaps = 2/64 (3%) Query: 35 EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEV--DKEATGKISFNDFLAV 92 E L+D + +GT+ + EL+ A+ ALG E+++ + ++ ++ G I ++ FLA Sbjct: 87 ECLKLYDKEENGTMLLAELQHALLALGESLDDEQVETLFADCMDPEDDEGFIPYSPFLAR 146 Query: 93 MTQK 96 M + Sbjct: 147 MCDR 150 >1DGU-A nrPDB Length = 183 Score = 49.7 bits (117), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 15/126 (11%) Query: 55 VAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT--QKMAEKDTKEEILKAFRL 112 +++ L P KE + ++ S A +SF DFL +++ A D K AFR+ Sbjct: 51 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRI 106 Query: 113 FDDDETGKISFKNLKRVANEL-GES----LTDEELQEMID----EADRDGDGEVNEEEFL 163 FD D+ G ++ ++L R+ N L GE L+ E++++ID E+D D DG +N EF Sbjct: 107 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 166 Query: 164 KIMKKT 169 ++ ++ Sbjct: 167 HVISRS 172 >2LM5-A nrPDB Length = 214 Score = 49.7 bits (117), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 39/126 (30%), Positives = 67/126 (53%), Gaps = 15/126 (11%) Query: 55 VAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT--QKMAEKDTKEEILKAFRL 112 +++ L P KE + ++ S A +SF DFL +++ A D K AFR+ Sbjct: 82 LSLPELKANPFKERICRVFST--SPAKDSLSFEDFLDLLSVFSDTATPDIKSHY--AFRI 137 Query: 113 FDDDETGKISFKNLKRVANEL-GES----LTDEELQEMID----EADRDGDGEVNEEEFL 163 FD D+ G ++ ++L R+ N L GE L+ E++++ID E+D D DG +N EF Sbjct: 138 FDFDDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQ 197 Query: 164 KIMKKT 169 ++ ++ Sbjct: 198 HVISRS 203 >4YZB-A nrPDB Length = 491 Score = 49.3 bits (116), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 44/155 (28%), Positives = 79/155 (50%), Gaps = 16/155 (10%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVA-----------MRALGFEPRKEEMKKMIS 74 T ++ E+ + F D +G G +D +EL + AL + E+++++ Sbjct: 334 TNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELMKLKGEDVSALDQSAIEFEVEQVLD 393 Query: 75 EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG 134 VD + G I +++F+ V + +++ + +AF +FD D +GKIS L A G Sbjct: 394 AVDFDKNGFIEYSEFVTVAMDRKTLL-SRQRLERAFGMFDADGSGKISSSEL---ATIFG 449 Query: 135 ESLTDEE-LQEMIDEADRDGDGEVNEEEFLKIMKK 168 S D E + ++ E DR+ DGEV+ EEF +++ K Sbjct: 450 VSEVDSETWRRVLAEVDRNNDGEVDFEEFRQMLLK 484 >1QX2-A nrPDB Length = 76 Score = 49.3 bits (116), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 34/73 (46%), Positives = 44/73 (60%), Gaps = 4/73 (5%) Query: 102 TKEEILKAFRLFDDDE--TGKISFKNLKRVANELGESLTD--EELQEMIDEADRDGDGEV 157 + EEI AF +F E +IS + LK V LG SL L EMI+E D++GDGEV Sbjct: 3 SPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEV 62 Query: 158 NEEEFLKIMKKTN 170 + EEFL +MKK + Sbjct: 63 SFEEFLVMMKKIS 75 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 41/67 (61%), Gaps = 4/67 (5%) Query: 31 QEVREAFDLFDS-DG-SGTIDVKELKVAMRALGFEPRK--EEMKKMISEVDKEATGKISF 86 +E++ AF++F + +G I +ELK+ M+ LG K + +MI EVDK G++SF Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEVSF 64 Query: 87 NDFLAVM 93 +FL +M Sbjct: 65 EEFLVMM 71 >4N5X-A nrPDB Length = 199 Score = 49.3 bits (116), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 70/139 (50%), Gaps = 8/139 (5%) Query: 26 TEDQKQEVR--EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ++D +Q R F D +G G +D+ EL+ +R LG ++ +K+ + D GK Sbjct: 15 SQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGK 74 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 + F +F+ + KD ++++ AF+ D + GKI + + LG ++++++ + Sbjct: 75 LDFEEFMKYL------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAE 128 Query: 144 EMIDEADRDGDGEVNEEEF 162 ++ D DG V+ E+ Sbjct: 129 LILQSIDVDGTMTVDWNEW 147 Score = 27.3 bits (59), Expect = 3.3, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 38/78 (48%), Gaps = 2/78 (2%) Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 L + AE+ T+ E L F+ D + G + L+ LG L + +++ Sbjct: 10 LPTAASQDAEQPTRYETL--FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTG 67 Query: 150 DRDGDGEVNEEEFLKIMK 167 D + DG+++ EEF+K +K Sbjct: 68 DVNKDGKLDFEEFMKYLK 85 >4ZCV-A nrPDB Length = 165 Score = 48.9 bits (115), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 34/139 (24%), Positives = 69/139 (49%), Gaps = 8/139 (5%) Query: 26 TEDQKQEVR--EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +D +Q R F D +G G +D+ EL+ +R LG ++ +K+ + D GK Sbjct: 6 CQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGK 65 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 + F +F+ + KD ++++ AF+ D + GKI + + LG ++++++ + Sbjct: 66 LDFEEFMKYL------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAE 119 Query: 144 EMIDEADRDGDGEVNEEEF 162 ++ D DG V+ E+ Sbjct: 120 LILQSIDVDGTMTVDWNEW 138 Score = 26.9 bits (58), Expect = 4.4, Method: Compositional matrix adjust. Identities = 20/70 (28%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 98 AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEV 157 AE+ T+ E L F+ D + G + L+ LG L + +++ D + DG++ Sbjct: 9 AEQPTRYETL--FQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKL 66 Query: 158 NEEEFLKIMK 167 + EEF+K +K Sbjct: 67 DFEEFMKYLK 76 >4AOM-A nrPDB Length = 146 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 6/97 (6%) Query: 46 GTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG-KISFNDFLAVMTQKMAEKDTKE 104 G I + R LG P + KK+ KE G +++ +L ++ + +KD E Sbjct: 30 GKISIDNASYNARKLGLAPSSIDEKKI-----KELYGDNLTYEQYLEYLSICVHDKDNVE 84 Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 E++K F FD++ TG ++ +K + G++LTD+E Sbjct: 85 ELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQE 121 >3TZ1-A nrPDB Length = 74 Score = 47.8 bits (112), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 25/66 (37%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E+ +AFR+ D ++ G I L+ + LG+ LT++E++ MI E D DG G V+ EEF Sbjct: 8 ELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFKC 67 Query: 165 IMKKTN 170 +M ++ Sbjct: 68 LMMSSD 73 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 40/63 (63%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 +E++EAF + D + G I V L+ +++LG E ++E++ MI+E D + +G + + +F Sbjct: 7 RELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFK 66 Query: 91 AVM 93 +M Sbjct: 67 CLM 69 >1OZS-A nrPDB Length = 73 Score = 47.8 bits (112), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 45/66 (68%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 ++EE+ FR+FD + G I + LK + GE++T+++++E++ + D++ DG ++ +E Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDE 64 Query: 162 FLKIMK 167 FL+ MK Sbjct: 65 FLEFMK 70 Score = 43.1 bits (100), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 19/63 (30%), Positives = 42/63 (66%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 +E+ + F +FD + G ID++ELK+ ++A G ++++++++ + DK G+I +++FL Sbjct: 7 EELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDEFL 66 Query: 91 AVM 93 M Sbjct: 67 EFM 69 >1GJY-A nrPDB Length = 167 Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 9/91 (9%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 R+ F FDSD SGT+D +EL+ A+ +GF + + + +GKI+F+D++A Sbjct: 75 RQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRY--STSGKITFDDYIACC 132 Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 + A D+ FR D + G ++F Sbjct: 133 VKLRALTDS-------FRRRDSAQQGMVNFS 156 Score = 33.5 bits (75), Expect = 0.044, Method: Compositional matrix adjust. Identities = 26/108 (24%), Positives = 49/108 (45%), Gaps = 18/108 (16%) Query: 46 GTIDVKELKVAMR----ALGFEP-RKEEMKKMISEVDKEATGKISFNDF---LAVMTQKM 97 G ID EL+ + A G++P E + M+S +D++ +G + FN+F AV+ Sbjct: 16 GQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL---- 71 Query: 98 AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 + F FD D +G + + L++ +G L + + + Sbjct: 72 ------NGWRQHFISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSI 113 >4OCI-A nrPDB Length = 146 Score = 47.0 bits (110), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 32/135 (23%), Positives = 65/135 (48%), Gaps = 2/135 (1%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++++E+F LFD DG G + + E + +R LG + + K +S+ Sbjct: 4 HNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSK--VRGMSYEL 61 Query: 89 FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDE 148 F + +Q + K+EI A + D D+ G I L+R+ + +G+++ +E+ ++ Sbjct: 62 FTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITDLFTF 121 Query: 149 ADRDGDGEVNEEEFL 163 D G V ++F+ Sbjct: 122 MGIDEQGVVKVDDFI 136 >3AAJ-A nrPDB Length = 167 Score = 46.6 bits (109), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 33/123 (26%), Positives = 58/123 (47%), Gaps = 18/123 (14%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 + S F + N A ++ G +T+ Q F +D D SG ID ELK A+ Sbjct: 46 IISMFDRENKAGVNFSEFTGVWKYITDWQN-----VFRTYDRDNSGMIDKNELKQALS-- 98 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFL--AVMTQKMAEKDTKEEILKAFRLFDDDET 118 G+ + +I + D++ G+I+F+DF+ ++ Q++ + FR +D D+ Sbjct: 99 GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGCIVLQRLTD---------IFRRYDTDQD 149 Query: 119 GKI 121 G I Sbjct: 150 GWI 152 Score = 42.4 bits (98), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 34/133 (25%), Positives = 62/133 (46%), Gaps = 10/133 (7%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEP-RKEEMKKMISEVDKEATGKISFNDFLA 91 + F D D SG I EL+ A+ + P ++ +IS D+E ++F++F Sbjct: 6 LWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTG 65 Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 V ++ FR +D D +G I LK+ + G L+D+ +I + DR Sbjct: 66 VWKYITDWQN-------VFRTYDRDNSGMIDKNELKQALS--GYRLSDQFHDILIRKFDR 116 Query: 152 DGDGEVNEEEFLK 164 G G++ ++F++ Sbjct: 117 QGRGQIAFDDFIQ 129 >2K7C-A nrPDB Length = 72 Score = 46.2 bits (108), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 43/66 (65%), Gaps = 1/66 (1%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMR-ALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 +E+R+AF FD++G G I EL+ AMR LG + +++++I +VD G++ F +F Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEF 66 Query: 90 LAVMTQ 95 + +M++ Sbjct: 67 VRMMSR 72 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 40/65 (61%), Gaps = 1/65 (1%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E+ AFR FD + G+IS L+ +L G + +++E+I + D +GDG V+ EEF+ Sbjct: 8 ELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFV 67 Query: 164 KIMKK 168 ++M + Sbjct: 68 RMMSR 72 >2AUC-A nrPDB Length = 126 Score = 46.2 bits (108), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 26/112 (23%), Positives = 61/112 (54%), Gaps = 7/112 (6%) Query: 38 DLFDSDGS-GTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG-KISFNDFLAVMTQ 95 D+F++ S G + +++ R LG P + KK+ ++ G +++ +L +T Sbjct: 2 DMFNTKSSNGKLRIEDASHNARKLGLAPSSTDEKKI-----RDLYGDSLTYEQYLEYLTM 56 Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 + ++D EE++K F FD++ +G ++ +K + G++LT++E + ++ Sbjct: 57 CVHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALN 108 >2M97-A nrPDB Length = 69 Score = 45.8 bits (107), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 24/68 (35%), Positives = 42/68 (61%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 ++EE+ + FR+FD D G I + + GE LTDE++ E+ ++D D +G ++ +E Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 162 FLKIMKKT 169 FLK+M+ Sbjct: 61 FLKMMENV 68 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 39/64 (60%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 ++E+ E F +FD DG+G ID +E +R G + E++ ++ + D + G+I F++F Sbjct: 2 EEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEF 61 Query: 90 LAVM 93 L +M Sbjct: 62 LKMM 65 >1JC2-A nrPDB Length = 76 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 44/66 (66%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 ++EE+ FR+FD + G I + L + GE + +E++++++ ++D++ DG ++ +E Sbjct: 8 SEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDE 67 Query: 162 FLKIMK 167 FLK+M+ Sbjct: 68 FLKMME 73 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 40/64 (62%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 ++E+ F +FD + G ID++EL +RA G +E+++ ++ + DK G+I F++F Sbjct: 9 EEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDEF 68 Query: 90 LAVM 93 L +M Sbjct: 69 LKMM 72 >1JUO-A nrPDB Length = 198 Score = 45.1 bits (105), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/91 (29%), Positives = 46/91 (50%), Gaps = 9/91 (9%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 R+ F FD+D SGT+D +EL+ A+ +GF + + + GKI+F+D++A Sbjct: 106 RQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRY--STNGKITFDDYIACC 163 Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 + A D+ FR D + G ++F Sbjct: 164 VKLRALTDS-------FRRRDTAQQGVVNFP 187 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 27/116 (23%), Positives = 52/116 (44%), Gaps = 18/116 (15%) Query: 46 GTIDVKELKVAMR----ALGFEP-RKEEMKKMISEVDKEATGKISFNDF---LAVMTQKM 97 G ID EL+ + A G++P E + M+S +D++ +G + FN+F AV+ Sbjct: 47 GQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVL---- 102 Query: 98 AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + F FD D +G + + L++ +G L+ + + + +G Sbjct: 103 ------NGWRQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG 152 >5MWC-D nrPDB Length = 311 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 24/70 (34%), Positives = 41/70 (58%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 ++EE+ + FR FD D G I + + GE LTDE+ E+ ++D D +G ++ +E Sbjct: 149 SEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDE 208 Query: 162 FLKIMKKTNL 171 FLK+++ L Sbjct: 209 FLKMVENVQL 218 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 20/63 (31%), Positives = 35/63 (55%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 +E+ E F FD DG G ID +E +R G + E+ ++ + D + G+I F++FL Sbjct: 151 EELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFL 210 Query: 91 AVM 93 ++ Sbjct: 211 KMV 213 >5MRA-A nrPDB Length = 167 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 46/90 (51%), Gaps = 9/90 (10%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 R+ F FD+D SGT+D +EL+ A+ +GF + + + GKI+F+D++A Sbjct: 75 RQHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRY--STNGKITFDDYIACC 132 Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + A D+ FR D + G ++F Sbjct: 133 VKLRALTDS-------FRRRDTAQQGVVNF 155 Score = 34.3 bits (77), Expect = 0.026, Method: Compositional matrix adjust. Identities = 25/113 (22%), Positives = 51/113 (45%), Gaps = 12/113 (10%) Query: 46 GTIDVKELKVAMR----ALGFEP-RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEK 100 G ID EL+ + A G++P E + M+S +D++ +G + FN+F + + Sbjct: 16 GQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGWR 75 Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + F FD D +G + + L++ +G L+ + + + +G Sbjct: 76 -------QHFISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTNG 121 >1S6J-A nrPDB Length = 87 Score = 44.7 bits (104), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 41/71 (57%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E++ ++E F + D+D SGTI ELK ++ +G E + E+K ++ D + +G I Sbjct: 17 LSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTI 76 Query: 85 SFNDFLAVMTQ 95 + +F+A Sbjct: 77 DYGEFIAATVH 87 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 44/72 (61%), Gaps = 3/72 (4%) Query: 95 QKMAEKDTKEEI--LK-AFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + MAE+ ++EEI LK F++ D D +G I+F LK +G L + E+++++D AD Sbjct: 11 KHMAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADI 70 Query: 152 DGDGEVNEEEFL 163 D G ++ EF+ Sbjct: 71 DKSGTIDYGEFI 82 >1JF0-A nrPDB Length = 195 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 24/76 (31%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 9 NVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE 68 N+A+ + +P L + V FD+FD DGSGTI + E K R G P +E+ Sbjct: 94 NLANADLAKWARNEPTLIREWGDAV---FDIFDKDGSGTITLDEWKAYGRISGISPSEED 150 Query: 69 MKKMISEVDKEATGKI 84 +K D + +G++ Sbjct: 151 CEKTFQHCDLDNSGEL 166 >2VTG-A nrPDB Length = 150 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/81 (35%), Positives = 41/81 (50%), Gaps = 6/81 (7%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 +E + FD + G ID+ LK M LG EMKKMISEV + IS+ DF+ +M Sbjct: 53 KEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISYRDFVNMM 112 Query: 94 TQKMAEKDTKEEILKAFRLFD 114 K + +LK +F+ Sbjct: 113 LGK------RSAVLKLVMMFE 127 Score = 30.8 bits (68), Expect = 0.30, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 40/76 (52%), Gaps = 4/76 (5%) Query: 95 QKMAEKDTKEEILKAFRL----FDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 QK ++++ E L AF+ FD + G+I +LKR+ +LG T E+++MI E Sbjct: 37 QKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVT 96 Query: 151 RDGDGEVNEEEFLKIM 166 ++ +F+ +M Sbjct: 97 GGVSDTISYRDFVNMM 112 >5I2L-A nrPDB Length = 120 Score = 44.3 bits (103), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 47/94 (50%), Gaps = 3/94 (3%) Query: 8 SNVASTSYKRKVGPKPELTEDQKQEVREA---FDLFDSDGSGTIDVKELKVAMRALGFEP 64 S + +R P E E ++++++ F +D+ G ID+ ELK+ M LG Sbjct: 5 SGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQ 64 Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMA 98 +K MI EVD++ K+SF +FL + + A Sbjct: 65 THLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAA 98 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 22/62 (35%), Positives = 31/62 (50%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 K F+ +D G I LK + +LG T L+ MI E D D D +++ EFL I + Sbjct: 35 KMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKEVDEDFDSKLSFREFLLIFR 94 Query: 168 KT 169 K Sbjct: 95 KA 96 >5OTJ-D nrPDB Length = 110 Score = 43.9 bits (102), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 24/75 (32%), Positives = 43/75 (57%), Gaps = 4/75 (5%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQK 96 F FD++G G I + EL A+R LG +E+++M++E+D + G I FN+F++ Sbjct: 9 FKRFDTNGDGKISLSELTDALRTLG-STSADEVQRMMAEIDTDGDGFIDFNEFISFCN-- 65 Query: 97 MAEKDTKEEILKAFR 111 A +++ K F+ Sbjct: 66 -ANPGLMKDVAKVFK 79 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + F+ FD + GKIS L LG + DE +Q M+ E D DGDG ++ EF+ Sbjct: 7 RIFKRFDTNGDGKISLSELTDALRTLGSTSADE-VQRMMAEIDTDGDGFIDFNEFISFCN 65 >2LVK-A nrPDB Length = 77 Score = 43.9 bits (102), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 21/55 (38%), Positives = 36/55 (65%), Gaps = 1/55 (1%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLA 91 F FD++G G I + EL A+R LG +E+++M++E+D + G I FN+F++ Sbjct: 8 FKRFDTNGDGKISLSELTDALRTLG-STSADEVQRMMAEIDTDGDGFIDFNEFIS 61 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + F+ FD + GKIS L LG + DE +Q M+ E D DGDG ++ EF+ Sbjct: 6 RIFKRFDTNGDGKISLSELTDALRTLGSTSADE-VQRMMAEIDTDGDGFIDFNEFISFCN 64 >3BOW-B nrPDB Length = 184 Score = 43.5 bits (101), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 8/82 (9%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 FD+D SGTI EL A A GF + + MI + TG + F++F++ + + Sbjct: 97 FDTDRSGTIGSNELPGAFEAAGFHL-NQHIYSMIIRRYSDETGNMDFDNFISCLVR---- 151 Query: 100 KDTKEEILKAFRLFDDDETGKI 121 + + +AFR D + TG+I Sbjct: 152 ---LDAMFRAFRSLDKNGTGQI 170 >2R2I-A nrPDB Length = 198 Score = 43.1 bits (100), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 36/132 (27%), Positives = 64/132 (48%), Gaps = 9/132 (6%) Query: 45 SGTIDVKELKVAMRALGFEPRKEE-MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 SG + + E K P + +++M D G I F +++A ++ + K Sbjct: 29 SGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGK-VD 87 Query: 104 EEILKAFRLFDDDETGKISFKNLK------RVANELGESLTDEELQEMI-DEADRDGDGE 156 +++ F+L+D D G I L R N E++T EE M+ D+ D +GDGE Sbjct: 88 QKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGE 147 Query: 157 VNEEEFLKIMKK 168 ++ EEF++ ++K Sbjct: 148 LSLEEFMEGVQK 159 Score = 32.3 bits (72), Expect = 0.11, Method: Compositional matrix adjust. Identities = 21/67 (31%), Positives = 35/67 (52%), Gaps = 7/67 (10%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR------KEEMKKMI-SEVDKEATGK 83 Q++R F L+D DG+G ID EL ++A+ R EE M+ ++D G+ Sbjct: 88 QKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGE 147 Query: 84 ISFNDFL 90 +S +F+ Sbjct: 148 LSLEEFM 154 >1KFX-S nrPDB Length = 184 Score = 42.7 bits (99), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 8/82 (9%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 FD+D SGTI EL A A GF E + MI + +G + F++F++ + + Sbjct: 97 FDTDRSGTICSSELPGAFEAAGFHL-NEHLYNMIIRRYSDESGNMDFDNFISCLVR---- 151 Query: 100 KDTKEEILKAFRLFDDDETGKI 121 + + +AF+ D D TG+I Sbjct: 152 ---LDAMFRAFKSLDKDGTGQI 170 >2G2B-A nrPDB Length = 150 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 6/82 (7%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 +E + FD +G+G ID+ LK + LG E+KK+I EV + S+ DFL +M Sbjct: 54 KEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMM 113 Query: 94 TQKMAEKDTKEEILKAFRLFDD 115 K + ILK ++++ Sbjct: 114 LGK------RSAILKMILMYEE 129 Score = 29.6 bits (65), Expect = 0.72, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Query: 113 FDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEV-NEEEFLKIM 166 FD + G I +LKR+ +LG T EL+++I E G GE + +FL++M Sbjct: 60 FDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVS-SGSGETFSYPDFLRMM 113 >1QXP-A nrPDB Length = 900 Score = 41.6 bits (96), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 8/82 (9%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 F++D SGTI EL A A GF + + MI + TG + F++F++ + + A Sbjct: 813 FETDRSGTIGSNELPGAFEAAGFH-LNQHIYSMIIRRYSDETGNMDFDNFISCLVRLDA- 870 Query: 100 KDTKEEILKAFRLFDDDETGKI 121 + +AFR D + TG+I Sbjct: 871 ------MFRAFRSLDKNGTGQI 886 Score = 30.8 bits (68), Expect = 0.34, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 43/86 (50%), Gaps = 10/86 (11%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE-VDKEATGKISFNDFLAVMTQ 95 F FD D SG++ E+++A+ A GF+ + + +++ D E I F++F+ + + Sbjct: 613 FRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARFADDELI--IDFDNFVRCLVR 670 Query: 96 KMAEKDTKEEILKAFRLFDDDETGKI 121 E + K F+ D + TG I Sbjct: 671 -------LEILFKIFKQLDPENTGTI 689 >2D58-A nrPDB Length = 107 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/63 (36%), Positives = 34/63 (53%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 +E + FD +G+G ID+ LK + LG E+KK+I EV + S+ DFL +M Sbjct: 35 KEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFLRMM 94 Query: 94 TQK 96 K Sbjct: 95 LGK 97 Score = 29.3 bits (64), Expect = 0.97, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 31/55 (56%), Gaps = 2/55 (3%) Query: 113 FDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEV-NEEEFLKIM 166 FD + G I +LKR+ +LG T EL+++I E G GE + +FL++M Sbjct: 41 FDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVS-SGSGETFSYPDFLRMM 94 >2BEC-A nrPDB Length = 202 Score = 41.2 bits (95), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/74 (36%), Positives = 45/74 (60%), Gaps = 5/74 (6%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMID----EADRDGDGEV 157 + ++ AF+L+D D GKIS + +V + G +T+E+L+ + D EAD DGDG V Sbjct: 113 RNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAV 172 Query: 158 NEEEFLKIMKKTNL 171 + EF K ++K ++ Sbjct: 173 SFVEFTKSLEKMDV 186 Score = 35.0 bits (79), Expect = 0.019, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 5/92 (5%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL-GFEPRKEEMKKM----ISEV 76 KPE ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E Sbjct: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILK 108 D++ G +SF +F + + E+ ILK Sbjct: 165 DEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 >2E30-A nrPDB Length = 195 Score = 41.2 bits (95), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 26/68 (38%), Positives = 44/68 (64%), Gaps = 5/68 (7%) Query: 109 AFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEM----IDEADRDGDGEVNEEEFL 163 AFRL+D D+ KIS L +V + G +++DE+L + I EAD+DGD ++ EF+ Sbjct: 118 AFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFV 177 Query: 164 KIMKKTNL 171 K+++K ++ Sbjct: 178 KVLEKVDV 185 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 7/79 (8%) Query: 20 GPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL-GFEPRKEEMKKM----IS 74 GP+P + ++ AF L+D D I EL +R + G E++ + I Sbjct: 104 GPEP--LNSRSNKLHFAFRLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQ 161 Query: 75 EVDKEATGKISFNDFLAVM 93 E D++ ISF +F+ V+ Sbjct: 162 EADQDGDSAISFTEFVKVL 180 >2OPO-A nrPDB Length = 86 Score = 40.8 bits (94), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/69 (39%), Positives = 41/69 (59%), Gaps = 4/69 (5%) Query: 97 MAEKDTKEEIL---KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 MA +DT ++I + F+ FD + GKIS L LG S+T +E++ M+ E D DG Sbjct: 1 MAAEDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLG-SVTPDEVRRMMAEIDTDG 59 Query: 154 DGEVNEEEF 162 DG ++ +EF Sbjct: 60 DGFISFDEF 68 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 40/66 (60%), Gaps = 4/66 (6%) Query: 27 EDQKQEVRE---AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ED Q++ + F FD++G G I EL A++ LG +E+++M++E+D + G Sbjct: 4 EDTPQDIADRERIFKRFDTNGDGKISSSELGDALKTLG-SVTPDEVRRMMAEIDTDGDGF 62 Query: 84 ISFNDF 89 ISF++F Sbjct: 63 ISFDEF 68 >1TIZ-A nrPDB Length = 67 Score = 40.4 bits (93), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 20/61 (32%), Positives = 34/61 (55%) Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + F FD ++ GK+S + VA T E++ + +E D DG+GE+N +EF ++ Sbjct: 5 RVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSCIE 64 Query: 168 K 168 K Sbjct: 65 K 65 Score = 26.2 bits (56), Expect = 8.5, Method: Compositional matrix adjust. Identities = 15/66 (22%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPR--KEEMKKMISEVDKEATGKISFNDFLA 91 + F+ FD + G + + E + AL F P +E++ K E+D + G+++ ++F + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREV--ALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTS 61 Query: 92 VMTQKM 97 + + + Sbjct: 62 CIEKML 67 >1WY9-A nrPDB Length = 147 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 24/66 (36%), Positives = 36/66 (54%), Gaps = 4/66 (6%) Query: 35 EAFDL----FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 EAF + FD +G+G ID+ LK + LG E+K++I EV + S++DFL Sbjct: 48 EAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFL 107 Query: 91 AVMTQK 96 +M K Sbjct: 108 RMMLGK 113 Score = 30.4 bits (67), Expect = 0.44, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 34/64 (53%), Gaps = 4/64 (6%) Query: 107 LKAFRL----FDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 L+AF++ FD + G I +LKR+ +LG T EL+ +I E + + +F Sbjct: 47 LEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDF 106 Query: 163 LKIM 166 L++M Sbjct: 107 LRMM 110 >3PAT-A nrPDB Length = 110 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 33/102 (32%), Positives = 52/102 (50%), Gaps = 10/102 (9%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQK-MAEKDTKEEILKAFRLFDDDETGKISF 123 + +++KK + V +A G + F A++ K M+ D K K F+ D D +G I Sbjct: 8 KADDIKKALDAV--KAEGSFNHKKFFALVGLKAMSANDVK----KVFKAIDADASGFIEE 61 Query: 124 KNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVNEEEF 162 + LK V G LTD E + + AD+DGDG++ +EF Sbjct: 62 EELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEF 103 Score = 33.1 bits (74), Expect = 0.057, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK---EEMKKMISEVDKEATGKISFN 87 +V++ F D+D SG I+ +ELK +++ + R E K + DK+ GKI + Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGID 101 Query: 88 DF 89 +F Sbjct: 102 EF 103 >1S36-A nrPDB Length = 195 Score = 40.4 bits (93), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 3/75 (4%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEM 69 +A++ K+ +P L + V FD+FD DGSGTI + E K + G P +E+ Sbjct: 95 LATSELKKWARNEPTLIREWGDAV---FDIFDKDGSGTITLDEWKAYGKISGISPSQEDC 151 Query: 70 KKMISEVDKEATGKI 84 + D + +G + Sbjct: 152 EATFRHCDLDNSGDL 166 >1H4B-A nrPDB Length = 84 Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 K E F FD++G G I EL A++ LG +E+K M++E+D + G ISF +F Sbjct: 8 KAERERIFKRFDANGDGKISAAELGEALKTLG-SITPDEVKHMMAEIDTDGDGFISFQEF 66 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 24/60 (40%), Positives = 35/60 (58%), Gaps = 1/60 (1%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K E + F+ FD + GKIS L LG S+T +E++ M+ E D DGDG ++ +EF Sbjct: 8 KAERERIFKRFDANGDGKISAAELGEALKTLG-SITPDEVKHMMAEIDTDGDGFISFQEF 66 >2I94-A nrPDB Length = 202 Score = 40.0 bits (92), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 26/101 (25%), Positives = 47/101 (46%), Gaps = 1/101 (0%) Query: 67 EEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 EE+ KE +G+I+ +F + ++ E D K FR FD + G + FK Sbjct: 26 EELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADPKAYAQHVFRSFDANSDGTLDFKE 85 Query: 126 LKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + T+++L+ D DG+G +++ E L+I+ Sbjct: 86 YVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIV 126 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 3/80 (3%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D K + F FD++ GT+D KE +A+ ++++ S D + G IS N Sbjct: 61 DPKAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKN 120 Query: 88 DFLAVMT---QKMAEKDTKE 104 + L ++T + ++ +DTK Sbjct: 121 EVLEIVTAIFKMISPEDTKH 140 >5T7C-A nrPDB Length = 193 Score = 39.3 bits (90), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 11/107 (10%) Query: 35 EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM- 93 F FD++G GTID +E +A+ ++++K S D + G IS ++ L ++ Sbjct: 67 HVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQ 126 Query: 94 --------TQKMAEKDTKEE--ILKAFRLFDDDETGKISFKNLKRVA 130 KM E ++ E K FR D + GK+S + R A Sbjct: 127 AIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGA 173 Score = 32.0 bits (71), Expect = 0.13, Method: Compositional matrix adjust. Identities = 19/88 (21%), Positives = 38/88 (43%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TG ++ ++F + D + FR FD + G I F+ + + Sbjct: 39 PTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLE 98 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMK 167 ++L+ D DG+G ++ E L+I++ Sbjct: 99 QKLKWAFSMYDLDGNGYISRSEMLEIVQ 126 >2G9B-A nrPDB Length = 263 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 39/150 (26%), Positives = 71/150 (47%), Gaps = 24/150 (16%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKE-------EMKKMISEVDKEATGKISFNDFLAV 92 FD+DGSG ++ KEL+ ++ L + RK+ EMK + + + GKI + V Sbjct: 25 FDADGSGYLEGKELQNLIQEL-LQARKKAGLELSPEMKTFVDQYGQRDDGKIGIVELAHV 83 Query: 93 MTQ--------KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE----SLTDE 140 + + + + EE +K +R +D D +G I + LK +L E ++ D Sbjct: 84 LPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKANKTVDDT 143 Query: 141 ELQE----MIDEADRDGDGEVNEEEFLKIM 166 +L E M+ D + DG++ E +++ Sbjct: 144 KLAEYTDLMLKLFDSNNDGKLELTEMARLL 173 Score = 30.8 bits (68), Expect = 0.28, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 25/39 (64%), Gaps = 1/39 (2%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEM 69 +E +AF+L+D DG+G ID EL ++ L E K+E+ Sbjct: 191 KEFNKAFELYDQDGNGYIDENELDALLKDLC-EKNKQEL 228 >3KPX-A nrPDB Length = 198 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 4/64 (6%) Query: 25 LTEDQKQEVRE----AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 ++++K +R FD+FD DGSG+I + E K G P E+ +K D + Sbjct: 106 WSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEWKTYGGISGICPSDEDAEKTFKHCDLDN 165 Query: 81 TGKI 84 +GK+ Sbjct: 166 SGKL 169 Score = 28.9 bits (63), Expect = 1.1, Method: Compositional matrix adjust. Identities = 36/157 (22%), Positives = 62/157 (39%), Gaps = 22/157 (14%) Query: 27 EDQKQEVRE--AFDLFDSDGSGTIDVKELKV-----AMRALGFEP-----RKEEMKKMIS 74 ED K R F+ D +G+G I + E+ LG P +E ++ Sbjct: 17 EDPKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFK 76 Query: 75 EVDKEATGKISFNDF------LAVMTQKMAEKDTKEEILK----AFRLFDDDETGKISFK 124 ++ + ++ F F LA K+ ++ K I F +FD D +G IS Sbjct: 77 KIGLDYGKEVEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLD 136 Query: 125 NLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 K G +DE+ ++ D D G+++ +E Sbjct: 137 EWKTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDE 173 >1F4Q-A nrPDB Length = 165 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 20/68 (29%), Positives = 36/68 (52%), Gaps = 2/68 (2%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 +E F D DGSGT++ EL+ A+ +G+ + + ++ K G+I F+D++A Sbjct: 73 KENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKN--GRIFFDDYVACC 130 Query: 94 TQKMAEKD 101 + A D Sbjct: 131 VKLRALTD 138 Score = 38.5 bits (88), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/113 (23%), Positives = 51/113 (45%), Gaps = 12/113 (10%) Query: 46 GTIDVKELKVAMRALG----FEPRK-EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEK 100 G +D +EL+ + G + P E + MI+ +D++ TGK+ FN F + A K Sbjct: 14 GEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWAALNAWK 73 Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + F D D +G + L++ +G L+ + L ++ ++G Sbjct: 74 EN-------FMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKNG 119 >3E3R-A nrPDB Length = 204 Score = 38.9 bits (89), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 60/118 (50%), Gaps = 8/118 (6%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 +D +GSGT+D++E A+R + R+ + +++D+ G ++ +D V + + Sbjct: 82 WDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHP 141 Query: 100 K-----DTKEEILKAFR-LFDDDET-GKISFKNLKRVANELGESL-TDEELQEMIDEA 149 K T++E+L+ F FD E G+++ + + + S+ TDEE M+ A Sbjct: 142 KVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAMMTSA 199 Score = 29.3 bits (64), Expect = 0.89, Method: Compositional matrix adjust. Identities = 16/64 (25%), Positives = 33/64 (51%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 + + + FR D D + + ++ +LG L E + + + DR+G G ++ EEFL Sbjct: 37 QGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFL 96 Query: 164 KIMK 167 + ++ Sbjct: 97 RALR 100 >1BJF-A nrPDB Length = 193 Score = 38.1 bits (87), Expect = 0.002, Method: Compositional matrix adjust. Identities = 31/114 (27%), Positives = 50/114 (43%), Gaps = 11/114 (9%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + F FD++G GTID +E +A+ ++++K S D + G IS Sbjct: 60 DASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKA 119 Query: 88 DFLAVM---------TQKMAEKDTKEE--ILKAFRLFDDDETGKISFKNLKRVA 130 + L ++ KM E ++ E K FR D + GK+S + R A Sbjct: 120 EMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGA 173 Score = 30.8 bits (68), Expect = 0.35, Method: Compositional matrix adjust. Identities = 19/88 (21%), Positives = 38/88 (43%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 +G +S +F + D + FR FD + G I F+ + + Sbjct: 39 PSGHLSMEEFKKIYGNFFPYGDASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLE 98 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMK 167 ++L+ D DG+G +++ E L+I++ Sbjct: 99 QKLKWAFSMYDLDGNGYISKAEMLEIVQ 126 >5VT9-A nrPDB Length = 152 Score = 37.7 bits (86), Expect = 0.003, Method: Compositional matrix adjust. Identities = 33/136 (24%), Positives = 59/136 (43%), Gaps = 7/136 (5%) Query: 32 EVREAFDLFDSDGSGT-IDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 E E + F++ SG + + + R LG P + K+ E + SF F+ Sbjct: 18 EADEMYARFNARASGGKVSTGDAMILARQLGLAPSYAD-KQAFEEKSGDNLDYASFQKFV 76 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 T +D E++++AF FD + G ++ K + + GE LT EE + A+ Sbjct: 77 GTSTHP---EDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTEEFNALA--AE 131 Query: 151 RDGDGEVNEEEFLKIM 166 +++ +F K M Sbjct: 132 YFTSDQIDYRQFCKAM 147 >4GFT-A nrPDB Length = 69 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 16/44 (36%), Positives = 28/44 (63%) Query: 98 AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 +KD EE++K F FD++ TG ++ +K + G++LTD+E Sbjct: 1 GDKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQE 44 >1A75-A nrPDB Length = 108 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/69 (33%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLK---RVANELGESLTDEELQEMIDEADRDGDGEVN 158 + ++I KAF D D++G I LK +V +LTD E + + D DGDG + Sbjct: 39 SADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAFLKAGDSDGDGAIG 98 Query: 159 EEEFLKIMK 167 EE++ ++K Sbjct: 99 VEEWVALVK 107 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 39/85 (45%), Gaps = 4/85 (4%) Query: 12 STSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK---EE 68 S SYK K L+ ++++AF D D SG I+ ELK+ ++ R E Sbjct: 23 SFSYKAFF-AKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAE 81 Query: 69 MKKMISEVDKEATGKISFNDFLAVM 93 K + D + G I +++A++ Sbjct: 82 TKAFLKAGDSDGDGAIGVEEWVALV 106 >2M7L-A nrPDB Length = 144 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/97 (23%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 20 GPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF------EPRKEEMKKMI 73 G +T +Q QE +++FD FD + G +D E + + ++G + + Sbjct: 1 GSSSGVTAEQMQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIY 60 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 + V K G +SF++++ M +K E + E++ + F Sbjct: 61 NNVTKGENG-VSFDNYVQYMKEKNDENPSPEQLNEIF 96 >1NP8-A nrPDB Length = 159 Score = 37.4 bits (85), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 8/75 (10%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 FD+D SGTI EL A A GF + + MI + TG + F++F++ + + Sbjct: 93 FDTDRSGTIGSNELPGAFEAAGFHL-NQHIYSMIIRRYSDETGNMDFDNFISCLVR---- 147 Query: 100 KDTKEEILKAFRLFD 114 + + +AFR D Sbjct: 148 ---LDAMFRAFRSLD 159 >2D8N-A nrPDB Length = 207 Score = 37.4 bits (85), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 41/87 (47%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TG+I+ F ++ + + D K FR FD + G + FK + T+ Sbjct: 47 PTGRITQQQFQSIYAKFFPDTDPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTN 106 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIM 166 ++L+ D DG+G +++ E L+I+ Sbjct: 107 QKLEWAFSLYDVDGNGTISKNEVLEIV 133 Score = 33.5 bits (75), Expect = 0.052, Method: Compositional matrix adjust. Identities = 19/66 (28%), Positives = 32/66 (48%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D K + F FDS+ GT+D KE +A+ ++++ S D + G IS N Sbjct: 68 DPKAYAQHVFRSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKN 127 Query: 88 DFLAVM 93 + L ++ Sbjct: 128 EVLEIV 133 >5XND-A nrPDB Length = 114 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/73 (30%), Positives = 39/73 (53%), Gaps = 11/73 (15%) Query: 102 TKEEILKAFRLFDDDETG-------KISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 + +E+ KAF + D D++G K+ +N K A +L+D E + + D DGD Sbjct: 45 STDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGAR----ALSDAETKAFLKAGDSDGD 100 Query: 155 GEVNEEEFLKIMK 167 G++ +EF ++K Sbjct: 101 GKIGIDEFAAMIK 113 Score = 31.6 bits (70), Expect = 0.18, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 37/72 (51%), Gaps = 3/72 (4%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK---EEMKKMISEVDKEAT 81 L+ EV++AF + D D SG I+ +ELK+ ++ R E K + D + Sbjct: 41 LSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGD 100 Query: 82 GKISFNDFLAVM 93 GKI ++F A++ Sbjct: 101 GKIGIDEFAAMI 112 >2NLN-A nrPDB Length = 108 Score = 37.0 bits (84), Expect = 0.005, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 34/61 (55%), Gaps = 3/61 (4%) Query: 110 FRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 FR D+D++G + LK + LT+ E + ++D AD DGDG++ +EF +++ Sbjct: 47 FRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADEFQEMV 106 Query: 167 K 167 Sbjct: 107 H 107 Score = 30.4 bits (67), Expect = 0.39, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR---KEEMKKMISEVDKEATGKISFND 88 +V++ F D+D SG +D ELK ++ + R + E K ++ D + GKI ++ Sbjct: 42 QVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKSLMDAADNDGDGKIGADE 101 Query: 89 F 89 F Sbjct: 102 F 102 >2JNX-A nrPDB Length = 134 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 35/133 (26%), Positives = 68/133 (51%), Gaps = 14/133 (10%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEE--MKKMISEVDKEATGKISFNDF----L 90 F D++G G++ +E+K + + P K E ++ + +D + G+I +F Sbjct: 6 FKQLDANGDGSVSYEEVKAFVSSK--RPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFAA 63 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 AV Q ++++ +IL ++L D D GK++ + + + G E++ + I +AD Sbjct: 64 AVKEQDLSDEKVGLKIL--YKLMDADGDGKLTKEEVTTFFKKFGY----EKVVDQIMKAD 117 Query: 151 RDGDGEVNEEEFL 163 +GDG + EEFL Sbjct: 118 ANGDGYITLEEFL 130 Score = 30.8 bits (68), Expect = 0.31, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 51/101 (50%), Gaps = 6/101 (5%) Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILK-AFRLFDDDETGKISFKNLKRVA 130 + ++D G +S+ + A ++ K K+ E++L+ F+ D D G+I + A Sbjct: 5 LFKQLDANGDGSVSYEEVKAFVSSKRPIKN--EQLLQLIFKAIDIDGNGEIDLAEFTKFA 62 Query: 131 NELGES-LTDEE--LQEMIDEADRDGDGEVNEEEFLKIMKK 168 + E L+DE+ L+ + D DGDG++ +EE KK Sbjct: 63 AAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKK 103 Score = 28.1 bits (61), Expect = 2.0, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D+K ++ + L D+DG G + +E+ + G+E +++ K D G I+ Sbjct: 72 DEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGYEKVVDQIMK----ADANGDGYITLE 127 Query: 88 DFLA 91 +FLA Sbjct: 128 EFLA 131 >4PAL-A nrPDB Length = 108 Score = 36.6 bits (83), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 36/67 (53%), Gaps = 3/67 (4%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEMIDEADRDGDGEVNEE 160 +++ KAF + D D++G I LK S LTD E + + + D+DGDG + + Sbjct: 41 DDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGDKDGDGMIGVD 100 Query: 161 EFLKIMK 167 EF ++K Sbjct: 101 EFAAMIK 107 Score = 31.2 bits (69), Expect = 0.22, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 43/86 (50%), Gaps = 8/86 (9%) Query: 14 SYKRK-VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE----- 67 S+K K K L +V++AF + D D SG I+ ELK+ ++ F P Sbjct: 23 SFKHKEFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQ--NFSPSARALTDA 80 Query: 68 EMKKMISEVDKEATGKISFNDFLAVM 93 E K +++ DK+ G I ++F A++ Sbjct: 81 ETKAFLADGDKDGDGMIGVDEFAAMI 106 >2L2E-A nrPDB Length = 190 Score = 36.6 bits (83), Expect = 0.006, Method: Compositional matrix adjust. Identities = 30/148 (20%), Positives = 70/148 (47%), Gaps = 15/148 (10%) Query: 30 KQEVREAFDLFDSDG-SGTIDVKEL-KVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 K+E+++ + F D SG ++ E K+ + F + + + D + G I F Sbjct: 24 KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAFAEYVFNVFDADKNGYIDFK 83 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL------------GE 135 +F+ ++ + + ++++ AF+L+D D G IS+ + R+ + + E Sbjct: 84 EFICALSV-TSRGELNDKLIWAFQLYDLDNNGLISYDEMLRIVDAIYKMVGSMVKLPEDE 142 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFL 163 ++ + ++ + D++ DG++ EEF Sbjct: 143 DTPEKRVNKIFNMMDKNKDGQLTLEEFC 170 >5JOL-A nrPDB Length = 82 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 42/75 (56%), Gaps = 4/75 (5%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKEL----KVAMRALGFEPRKEEMKKMISEVD 77 + +++++ E+REAF D+DG+G I EL K A L +E + +++ D Sbjct: 3 RGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGD 62 Query: 78 KEATGKISFNDFLAV 92 + G+ISF++F+ + Sbjct: 63 LDQDGRISFDEFIKI 77 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE----MIDEADRDGDGEVNEE 160 E+ +AF D D G ISF L + L ++E ++ D D DG ++ + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFD 72 Query: 161 EFLKIMK 167 EF+KI Sbjct: 73 EFIKIFH 79 >5JOJ-A nrPDB Length = 97 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 42/76 (55%), Gaps = 4/76 (5%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKEL----KVAMRALGFEPRKEEMKKMISEVD 77 + +++++ E+REAF D+DG+G I EL K A L +E + +++ D Sbjct: 3 RGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGD 62 Query: 78 KEATGKISFNDFLAVM 93 + G+ISF++F+ + Sbjct: 63 LDQDGRISFDEFIKIF 78 Score = 28.5 bits (62), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDE----ADRDGDGEVNEE 160 E+ +AF D D G ISF L + L ++E+ + D D DG ++ + Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISFD 72 Query: 161 EFLKIMK 167 EF+KI Sbjct: 73 EFIKIFH 79 >3SIA-A nrPDB Length = 220 Score = 36.2 bits (82), Expect = 0.007, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 32/65 (49%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 DQ + + F D D SGT+++ EL + G + +M+ D + G ISF Sbjct: 48 DQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTALRMMRIFDTDFNGHISFY 107 Query: 88 DFLAV 92 +F+A+ Sbjct: 108 EFMAM 112 >2KYF-A nrPDB Length = 108 Score = 36.2 bits (82), Expect = 0.008, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGE 156 K + ++ + FR+ D+D++G I LK LT E + + AD DGDG+ Sbjct: 37 KKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGK 96 Query: 157 VNEEEFLKIMK 167 + EEF ++++ Sbjct: 97 IGAEEFQEMVQ 107 Score = 27.3 bits (59), Expect = 3.6, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 3/92 (3%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 +A+ R + +K +++ +++E F + D+D SG I+ ELK ++ Sbjct: 11 IAAALRDCQAPDSFSPKKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRF 70 Query: 61 GFEPR---KEEMKKMISEVDKEATGKISFNDF 89 R E K ++ D + GKI +F Sbjct: 71 ESGARVLTASETKTFLAAADHDGDGKIGAEEF 102 >1BU3-A nrPDB Length = 109 Score = 35.8 bits (81), Expect = 0.009, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 38/69 (55%), Gaps = 3/69 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLK---RVANELGESLTDEELQEMIDEADRDGDGEVN 158 + ++I KAF + D D++G I LK +V + +LTD E + + D DGDG + Sbjct: 40 SADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGDSDGDGAIG 99 Query: 159 EEEFLKIMK 167 +E+ ++K Sbjct: 100 VDEWAALVK 108 Score = 28.9 bits (63), Expect = 1.2, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 36/76 (47%), Gaps = 3/76 (3%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK---EEMKKMISEVD 77 K LT ++++AF + D D SG I+ ELK+ ++ R E K + D Sbjct: 32 AKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAFLKAGD 91 Query: 78 KEATGKISFNDFLAVM 93 + G I +++ A++ Sbjct: 92 SDGDGAIGVDEWAALV 107 >2KQY-A nrPDB Length = 108 Score = 35.4 bits (80), Expect = 0.012, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEMIDEADRDGDGEVN 158 T ++I K F + D D++G I + L+ S LT E + + D DGDG++ Sbjct: 39 TPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAFLAAGDTDGDGKIG 98 Query: 159 EEEFLKIMK 167 EEF ++K Sbjct: 99 VEEFQSLVK 107 >5CPV-A nrPDB Length = 109 Score = 35.0 bits (79), Expect = 0.015, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 36/69 (52%), Gaps = 3/69 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVN 158 + +++ KAF + D D++G I LK +LTD E + + D DGDG++ Sbjct: 40 SADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGDSDGDGKIG 99 Query: 159 EEEFLKIMK 167 +EF ++K Sbjct: 100 VDEFTALVK 108 Score = 33.1 bits (74), Expect = 0.059, Method: Compositional matrix adjust. Identities = 23/76 (30%), Positives = 38/76 (50%), Gaps = 3/76 (3%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRK---EEMKKMISEVD 77 K LT +V++AF + D D SG I+ ELK+ ++ + R E K + D Sbjct: 32 AKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLKAGD 91 Query: 78 KEATGKISFNDFLAVM 93 + GKI ++F A++ Sbjct: 92 SDGDGKIGVDEFTALV 107 >3DD4-A nrPDB Length = 229 Score = 35.0 bits (79), Expect = 0.016, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 40/87 (45%) Query: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDE 140 +G ++ F + +Q + D+ F FD D G +SF++ + + L E Sbjct: 79 SGVVNEETFKEIYSQFFPQGDSTTYAHFLFNAFDTDHNGAVSFEDFIKGLSILLRGTVQE 138 Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMK 167 +L + D + DG + +EE L IMK Sbjct: 139 KLNWAFNLYDINKDGYITKEEMLDIMK 165 >5E1J-A nrPDB Length = 741 Score = 35.0 bits (79), Expect = 0.016, Method: Composition-based stats. Identities = 32/110 (29%), Positives = 55/110 (50%), Gaps = 7/110 (6%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVRE-AFDLFDSDGSGTIDVKE-LKVAMRALGFE--PR 65 V S+K ++ + + K+ + E AF L DSD +G ID + +K+ + + P+ Sbjct: 303 VVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPK 362 Query: 66 --KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLF 113 KEE + E+D KI+ ++F A + Q +A + KEE+ F F Sbjct: 363 ISKEEFGLIFDELDDTRDFKINKDEF-ADLCQAIALRFQKEEVPSLFEHF 411 Score = 34.7 bits (78), Expect = 0.023, Method: Composition-based stats. Identities = 28/118 (23%), Positives = 52/118 (44%), Gaps = 27/118 (22%) Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDET 118 A+ ++ KE++ K +S +D+ M ++M EK AF L D D+ Sbjct: 302 AVVYDSFKEQLAKQVSGMDQ--------------MKRRMLEK--------AFGLIDSDKN 339 Query: 119 GKISFKNLKRVANELGE-----SLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 G+I ++ +L ++ EE + DE D D ++N++EF + + L Sbjct: 340 GEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIAL 397 >3AKA-A nrPDB Length = 166 Score = 35.0 bits (79), Expect = 0.017, Method: Compositional matrix adjust. Identities = 37/154 (24%), Positives = 62/154 (40%), Gaps = 25/154 (16%) Query: 37 FDLFDSDGSGTIDVKELKVAMRAL----GFEPRKEE-----------MKKMISEVDKEAT 81 F FD DG+G ID + A +AL G R + + + D++ Sbjct: 10 FTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGLAGIADRDGD 69 Query: 82 GKISFNDFLAVMTQKMAEK-DTKEEILKAF-----RLFDDDETGKISFKNLKRVANELGE 135 +I+ +F+ +++ +K D EI + F + D D G ++ + R G Sbjct: 70 QRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADTARALTAFG- 128 Query: 136 SLTDEELQEMIDEA-DRDGDGEVNEEEFLKIMKK 168 E+L A D DGDG+V E E + + Sbjct: 129 --VPEDLARQAAAALDTDGDGKVGETEIVPAFAR 160 >1YX7-A nrPDB Length = 83 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 6/67 (8%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKV------AMRALGFEPRKEEMKKMISEVDKEATGK 83 K E+ AF D++G G + EL+ A +AL + KE K+I DK + GK Sbjct: 6 KAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 84 ISFNDFL 90 IS +FL Sbjct: 66 ISKEEFL 72 Score = 26.6 bits (57), Expect = 5.3, Method: Compositional matrix adjust. Identities = 19/68 (27%), Positives = 40/68 (58%), Gaps = 6/68 (8%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKR--VANELGESLTDEELQE----MIDEADRDGDG 155 K E+ AF+ D + G ++ L+ V + ++L+ ++++E +I AD++ DG Sbjct: 5 VKAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDG 64 Query: 156 EVNEEEFL 163 ++++EEFL Sbjct: 65 KISKEEFL 72 >2GGZ-A nrPDB Length = 211 Score = 35.0 bits (79), Expect = 0.018, Method: Compositional matrix adjust. Identities = 36/136 (26%), Positives = 64/136 (47%), Gaps = 18/136 (13%) Query: 45 SGTIDVKELKVAMRALGFEPRKEEMKKMISEV----DKEATGKISFNDFLAVMTQKMAEK 100 SG + E K LG + ++ K I +V D G + F +F+A + M EK Sbjct: 34 SGLQTLHEFKTL---LGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK 90 Query: 101 DTKEEILKAFRLFDDDETGKIS-------FKNLKRVANELGESLTDEELQEMI-DEADRD 152 ++++ F+L+D D G I F ++ + + ++L+ EE ++ + D + Sbjct: 91 -MEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQ--QTLSPEEFINLVFHKIDIN 147 Query: 153 GDGEVNEEEFLKIMKK 168 DGE+ EEF+ M K Sbjct: 148 NDGELTLEEFINGMAK 163 Score = 33.1 bits (74), Expect = 0.061, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 52/92 (56%), Gaps = 9/92 (9%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELK---VAMRALGFE---PRKEEMKKMISEVDK 78 + E +Q+++ F L+D+DG+G+ID EL +A++AL + +E + + ++D Sbjct: 87 MQEKMEQKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDI 146 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 G+++ +F+ M + ++D E + K+F Sbjct: 147 NNDGELTLEEFINGMAK---DQDLLEIVYKSF 175 >2JUL-A nrPDB Length = 256 Score = 35.0 bits (79), Expect = 0.019, Method: Compositional matrix adjust. Identities = 27/103 (26%), Positives = 45/103 (43%), Gaps = 1/103 (0%) Query: 66 KEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 K+E++ + E TG + + F + +Q + D F FD D G I F+ Sbjct: 90 KKELQSLYRGFKNECPTGLVDEDTFKLIYSQFFPQGDATTYAHFLFNAFDADGNGAIHFE 149 Query: 125 NLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + + L E+L+ + D + DG + +EE L IMK Sbjct: 150 DFVVGLSILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMK 192 Score = 34.3 bits (77), Expect = 0.030, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 52/110 (47%), Gaps = 15/110 (13%) Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILK-AFRLFDDDETGKIS----FKNL 126 + + D + G I F DF+ ++ + + T E LK AF L+D ++ G I+ + Sbjct: 134 LFNAFDADGNGAIHFEDFVVGLS--ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIM 191 Query: 127 KRVANELG--------ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 K + + +G E E ++ + DR+ DG V +EFL+ +K Sbjct: 192 KSIYDMMGRHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 >6EPA-A nrPDB Length = 187 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 36/87 (41%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 G ++ F+ + Q + D + FR+FD++ G I F+ R + D Sbjct: 39 PNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEFEEFIRALSITSRGNLD 98 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIM 166 E+L D D DG + EE I+ Sbjct: 99 EKLHWAFRLYDVDNDGYITREEMYNIV 125 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 21/97 (21%), Positives = 46/97 (47%), Gaps = 12/97 (12%) Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL--- 133 D+ G I F +F+ ++ + + E++ AFRL+D D G I+ + + + + + Sbjct: 73 DENNDGAIEFEEFIRALS-ITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQM 131 Query: 134 --------GESLTDEELQEMIDEADRDGDGEVNEEEF 162 E+ + + ++ D+ D++ D + EEF Sbjct: 132 VGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEF 168 >1TTX-A nrPDB Length = 109 Score = 34.7 bits (78), Expect = 0.023, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 37/69 (53%), Gaps = 3/69 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVN 158 + ++ FR D+D++G + + LK + LT+ E + ++ AD DGDG++ Sbjct: 40 SANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIG 99 Query: 159 EEEFLKIMK 167 EEF +++ Sbjct: 100 AEEFQEMVH 108 Score = 29.3 bits (64), Expect = 0.98, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 32/61 (52%), Gaps = 3/61 (4%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRAL---GFEPRKEEMKKMISEVDKEATGKISFND 88 +V++ F D+D SG +D +ELK ++ E + E K +++ D + GKI + Sbjct: 43 QVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKSLMAAADNDGDGKIGAEE 102 Query: 89 F 89 F Sbjct: 103 F 103 >2NA0-A nrPDB Length = 205 Score = 34.7 bits (78), Expect = 0.024, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 35/68 (51%), Gaps = 8/68 (11%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRAL-GFEP-------RKEEMKKMISEVDKEATG 82 Q++R F L+D DG+G ID EL +RA+ P +E + S++D G Sbjct: 90 QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDG 149 Query: 83 KISFNDFL 90 ++S +F+ Sbjct: 150 ELSLEEFM 157 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 33/133 (24%), Positives = 63/133 (47%), Gaps = 10/133 (7%) Query: 45 SGTIDVKELKVAMRALGFEPRKEE-MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 SG + + E + P + +++M D G I F ++ A ++ + K + Sbjct: 31 SGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNKDGYIDFMEYEAALSLVLKGK-VE 89 Query: 104 EEILKAFRLFDDDETGKISFKNLK------RVANELGES-LTDEELQEMI-DEADRDGDG 155 +++ F+L+D D G I L R N +S +T EE + + + D +GDG Sbjct: 90 QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDG 149 Query: 156 EVNEEEFLKIMKK 168 E++ EEF++ ++K Sbjct: 150 ELSLEEFMEGVQK 162 >1V1G-A nrPDB Length = 222 Score = 34.3 bits (77), Expect = 0.025, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR-VANELGE 135 D + G I F +F+ + E++ AF+L+D +TG I + LK V L E Sbjct: 84 DVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMVVALLHE 143 Query: 136 S---LTDEELQEMID----EADRDGDGEVNEEEF 162 S L+++ ++ M+D +ADR DG+++ +E+ Sbjct: 144 SELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEW 177 >1S6C-A nrPDB Length = 183 Score = 34.3 bits (77), Expect = 0.026, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 38/88 (43%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 +G ++ F + Q D F FD +TG + F++ + L Sbjct: 32 PSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVH 91 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMK 167 E+L+ + D + DG +N+EE + I+K Sbjct: 92 EKLRWTFNLYDINKDGYINKEEMMDIVK 119 >1S1E-A nrPDB Length = 224 Score = 34.3 bits (77), Expect = 0.027, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 38/88 (43%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 +G ++ F + Q D F FD +TG + F++ + L Sbjct: 65 PSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSVKFEDFVTALSILLRGTVH 124 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMK 167 E+L+ + D + DG +N+EE + I+K Sbjct: 125 EKLRWTFNLYDINKDGYINKEEMMDIVK 152 >4C0K-A nrPDB Length = 423 Score = 33.9 bits (76), Expect = 0.033, Method: Compositional matrix adjust. Identities = 33/149 (22%), Positives = 60/149 (40%), Gaps = 11/149 (7%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ELT K+ + F + D DG ++ EL + R P + ++ + V ++ Sbjct: 6 ELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQKNVPD 65 Query: 84 ISFND--------FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 +ND FL + + +T +L+ F D E + + ++ Sbjct: 66 GIYNDAVTLKGFLFLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKIPPGSST 125 Query: 136 SLTDEELQEMI---DEADRDGDGEVNEEE 161 L+ Q +I + DRDGDG ++ EE Sbjct: 126 ELSHRGQQFLIAVFERYDRDGDGALSPEE 154 >2M1U-A nrPDB Length = 93 Score = 33.9 bits (76), Expect = 0.034, Method: Compositional matrix adjust. Identities = 21/73 (28%), Positives = 35/73 (47%), Gaps = 1/73 (1%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 P+ D+K ++ EAF FD D G + V+E + +R G + E+ + D Sbjct: 16 PRGSHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEAADPNN 74 Query: 81 TGKISFNDFLAVM 93 TG I + F A++ Sbjct: 75 TGFIDYKAFAAML 87 Score = 32.0 bits (71), Expect = 0.14, Method: Compositional matrix adjust. Identities = 17/71 (23%), Positives = 37/71 (52%), Gaps = 1/71 (1%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 D K ++++AF FD D G +S + + + + G +T+ E+ E + AD + G ++ Sbjct: 22 SDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEAADPNNTGFIDY 80 Query: 160 EEFLKIMKKTN 170 + F ++ + Sbjct: 81 KAFAAMLYSVD 91 >1IJ5-A nrPDB Length = 323 Score = 33.9 bits (76), Expect = 0.038, Method: Compositional matrix adjust. Identities = 31/134 (23%), Positives = 56/134 (41%), Gaps = 7/134 (5%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 +AS + ++ Y R KP L+E+ +R+ F GSG ++LK + Sbjct: 92 LASLLKDLEDDASGYNRLRPSKPMLSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKY 151 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 + +KK+ V+ + G++S+ +AV A ++ FR D + G Sbjct: 152 ADTIPEGPLKKLFVMVENDTKGRMSYITLVAVANDLAA-------LVADFRKIDTNSNGT 204 Query: 121 ISFKNLKRVANELG 134 +S K + LG Sbjct: 205 LSRKEFREHFVRLG 218 >4OKH-A nrPDB Length = 189 Score = 33.9 bits (76), Expect = 0.042, Method: Compositional matrix adjust. Identities = 24/96 (25%), Positives = 44/96 (45%), Gaps = 8/96 (8%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 ++ F +D+D SGTI+ E++ A+ GF ++ +I+ + I F+ F+ Sbjct: 88 QKIFKHYDTDQSGTINSYEMRNAVNDAGFHLNN-QLYDIITMRYADKHMNIDFDSFICCF 146 Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + E + +AF FD D G I L+ + Sbjct: 147 VR-------LEGMFRAFHAFDKDGDGIIKLNVLEWL 175 Score = 26.2 bits (56), Expect = 7.6, Method: Compositional matrix adjust. Identities = 12/38 (31%), Positives = 18/38 (47%) Query: 135 ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 T E + MI D DG G++N +EF + K + Sbjct: 50 HGFTLESCRSMIALMDTDGSGKLNLQEFHHLWNKIKAW 87 >5ZGM-A nrPDB Length = 110 Score = 33.5 bits (75), Expect = 0.042, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVN 158 ++ ++ + F + D D++G I + LK V G L+D E + ++ D D DG++ Sbjct: 40 SEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAGDSDHDGKIG 99 Query: 159 EEEFLKIMKKT 169 +EF K++ + Sbjct: 100 ADEFAKMVAQA 110 Score = 33.5 bits (75), Expect = 0.043, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 3/67 (4%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR---KEEMKKMISEVDKEATGKISFND 88 +V+E F++ D D SG I+ +ELK ++ R E K +++ D + GKI ++ Sbjct: 43 QVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDTETKALLAAGDSDHDGKIGADE 102 Query: 89 FLAVMTQ 95 F ++ Q Sbjct: 103 FAKMVAQ 109 >6AGI-A nrPDB Length = 382 Score = 33.5 bits (75), Expect = 0.043, Method: Compositional matrix adjust. Identities = 31/133 (23%), Positives = 65/133 (48%), Gaps = 6/133 (4%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 R AF++FD+DG+ +D KE V +K E +++ + +K A ++ + + Sbjct: 108 RIAFNMFDTDGNEMVDKKEFLVLQEIF---RKKNEKREIKGDEEKRAMLRLQLYGYHSP- 163 Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 T + + D +E + +++ T + F +L A+++ +TD L ++ + G Sbjct: 164 TNSVLKTDAEELVSRSYWDTLRRNTSQALFSDLAERADDITSLVTDTTL--LVHFFGKKG 221 Query: 154 DGEVNEEEFLKIM 166 E+N E+F + M Sbjct: 222 KAELNFEDFYRFM 234 >5PAL-A nrPDB Length = 109 Score = 33.5 bits (75), Expect = 0.050, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 36/67 (53%), Gaps = 3/67 (4%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR---KEEMKKMISEVDKEATGKISFND 88 +V+E F++ D D SG I+ +ELK ++ R E K +++ D + GKI ++ Sbjct: 42 QVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGADE 101 Query: 89 FLAVMTQ 95 F ++ Q Sbjct: 102 FAKMVAQ 108 Score = 33.1 bits (74), Expect = 0.057, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 36/71 (50%), Gaps = 3/71 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVN 158 T ++ + F + D D++G I + LK V G L D E + ++ D D DG++ Sbjct: 39 TDAQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIG 98 Query: 159 EEEFLKIMKKT 169 +EF K++ + Sbjct: 99 ADEFAKMVAQA 109 >1JFJ-A nrPDB Length = 134 Score = 33.1 bits (74), Expect = 0.060, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 54/104 (51%), Gaps = 6/104 (5%) Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILK-AFRLFDDDETGKISFKNLKRVA 130 + E+D G +S+ + A +++K A K+ E++L+ F+ D D G+I + Sbjct: 5 LFKEIDVNGDGAVSYEEVKAFVSKKRAIKN--EQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 131 NEL-GESLTDEE--LQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + G+ L+D++ L+ + D DGDG++ +EE KK + Sbjct: 63 GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGI 106 Score = 32.7 bits (73), Expect = 0.073, Method: Compositional matrix adjust. Identities = 33/131 (25%), Positives = 68/131 (51%), Gaps = 18/131 (13%) Query: 41 DSDGSGTIDVKELKVAM---RALGFEPRKEEMKKMI-SEVDKEATGKISFNDFL----AV 92 D +G G + +E+K + RA+ + E++ ++I +D + G+I N+F ++ Sbjct: 10 DVNGDGAVSYEEVKAFVSKKRAI----KNEQLLQLIFKSIDADGNGEIDQNEFAKFYGSI 65 Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 Q +++ ++L ++L D D GK++ + + + G E++ E + +AD + Sbjct: 66 QGQDLSDDKIGLKVL--YKLMDVDGDGKLTKEEVTSFFKKHGI----EKVAEQVMKADAN 119 Query: 153 GDGEVNEEEFL 163 GDG + EEFL Sbjct: 120 GDGYITLEEFL 130 >5M6C-E nrPDB Length = 193 Score = 32.7 bits (73), Expect = 0.075, Method: Compositional matrix adjust. Identities = 28/107 (26%), Positives = 46/107 (42%), Gaps = 11/107 (10%) Query: 35 EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM- 93 F FD++ GTID +E +A+ ++++ S D + G IS + L ++ Sbjct: 67 HVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQ 126 Query: 94 --------TQKMAEKDTKEE--ILKAFRLFDDDETGKISFKNLKRVA 130 KM E ++ E K FR D + GK+S + R A Sbjct: 127 AIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGA 173 Score = 32.3 bits (72), Expect = 0.099, Method: Compositional matrix adjust. Identities = 31/164 (18%), Positives = 76/164 (46%), Gaps = 22/164 (13%) Query: 22 KPELTEDQKQ-------EVREAFDLFDSDG-SGTIDVKELK-VAMRALGFEPRKEEMKKM 72 +PE+ +D ++ E++E + F D +G ++V E K + + + + + Sbjct: 9 RPEMLQDLRENTEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHV 68 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 D + G I F +F+ ++ + +++++ AF ++D D G IS + + + Sbjct: 69 FRNFDTNSDGTIDFREFIIALSVT-SRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQA 127 Query: 133 L------------GESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + ES ++ +++ + D + DG+++ EEF++ Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIR 171 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 20/88 (22%), Positives = 38/88 (43%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TG ++ ++F + D + FR FD + G I F+ + + Sbjct: 39 PTGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLE 98 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMK 167 ++L D DG+G ++ EE L+I++ Sbjct: 99 QKLMWAFSMYDLDGNGYISREEMLEIVQ 126 >3CS1-A nrPDB Length = 219 Score = 32.3 bits (72), Expect = 0.095, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 33/59 (55%), Gaps = 1/59 (1%) Query: 37 FDLFDSDGSGTIDVKELKVAMRAL-GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 FD D+ G+ +D +E K A+ L + + E+ + E+DK TG ++F++F A + Sbjct: 136 FDEIDASGNMLVDEEEFKRAVPKLEAWGAKVEDPAALFKELDKNGTGSVTFDEFAAWAS 194 >4P5X-A nrPDB Length = 315 Score = 32.3 bits (72), Expect = 0.097, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES 136 D+ G IS+ +FLA + A + AF+LFD G+++F+N+K + G++ Sbjct: 69 DQTKDGLISYQEFLAFESVLCAPDSM---FIVAFQLFDKSGNGEVTFENVKEI---FGQT 122 Query: 137 LTDEEL 142 + + Sbjct: 123 IIHHHI 128 >5CUY-A nrPDB Length = 414 Score = 32.3 bits (72), Expect = 0.10, Method: Compositional matrix adjust. Identities = 27/101 (26%), Positives = 48/101 (47%), Gaps = 12/101 (11%) Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKIS 122 EP +E + + +SE+D A K +DF M +K+ + F FD G ++ Sbjct: 49 EPIQEAVDRKVSELDLAAYDK---DDFTQPMIKKIMSR--------LFSAFDVTHLGYLT 97 Query: 123 FKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 ++ V LG +++D +++ M E + DG V E+F Sbjct: 98 PDKVEEVCRYLGRNMSDGDVKAMKAEINAI-DGHVTFEKFW 137 >5ZH6-A nrPDB Length = 107 Score = 32.0 bits (71), Expect = 0.12, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 3/72 (4%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR---KEEMKKMISEVDKEAT 81 LT + + FD+ D D SG I+V ELK+ ++ R + E ++ D + Sbjct: 34 LTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETETNAFLAAGDSDHD 93 Query: 82 GKISFNDFLAVM 93 GKI ++F A++ Sbjct: 94 GKIGVDEFKAMV 105 Score = 28.1 bits (61), Expect = 1.8, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 39/90 (43%), Gaps = 12/90 (13%) Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETG-------KISFKNLKRVANELGESL 137 SFN +T + K + + K F + D D +G K+ +N A EL E+ Sbjct: 22 SFNHKTFFVTSGLTNK-SDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDET- 79 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 E + D D DG++ +EF ++K Sbjct: 80 ---ETNAFLAAGDSDHDGKIGVDEFKAMVK 106 >2ZFD-A nrPDB Length = 226 Score = 32.0 bits (71), Expect = 0.12, Method: Compositional matrix adjust. Identities = 42/169 (24%), Positives = 80/169 (47%), Gaps = 25/169 (14%) Query: 15 YKRKVG-PKPEL----TEDQKQEVREAFDLFDSDGS-----GTIDVKELKVAMRALGFEP 64 YK+ G PEL T E+ ++LF S G I+ +E ++A+ F+ Sbjct: 24 YKQSGGLGDPELLARDTVFSVSEIEALYELFKKISSAVIDDGLINKEEFQLAL----FKT 79 Query: 65 RKEE---MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 K+E ++ D + G + F +F ++ ++I +F+L+D + G I Sbjct: 80 NKKESLFADRVFDLFDTKHNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFI 139 Query: 122 SFKNLKRVA----NELGESLTDEELQEMID----EADRDGDGEVNEEEF 162 + +K++ E G +L D ++++ID EAD DG++++EE+ Sbjct: 140 ERQEVKQMVVATLAESGMNLKDTVIEDIIDKTFEEADTKHDGKIDKEEW 188 >4P5W-A nrPDB Length = 411 Score = 32.0 bits (71), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 3/67 (4%) Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKIS 122 +P + ++ + VD+ G ISF +F+A + A + AF+LFD G+++ Sbjct: 74 QPNPKTVELLSGVVDQTKDGLISFQEFVAFESVLCAPDAL---FMVAFQLFDKAGKGEVT 130 Query: 123 FKNLKRV 129 F+++K+V Sbjct: 131 FEDVKQV 137 >1UHN-A nrPDB Length = 189 Score = 32.0 bits (71), Expect = 0.15, Method: Compositional matrix adjust. Identities = 35/147 (23%), Positives = 72/147 (48%), Gaps = 20/147 (13%) Query: 32 EVREAFDLFDSDGS-----GTIDVKELKVAMRALGFEPRKEE---MKKMISEVDKEATGK 83 E+ ++LF S G I+ +E ++A+ F+ K+E ++ D + G Sbjct: 15 EIEALYELFKKISSAVIDDGLINKEEFQLAL----FKTNKKESLFADRVFDLFDTKHNGI 70 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA----NELGESLTD 139 + F +F ++ ++I +F+L+D + G I + +K++ E G +L D Sbjct: 71 LGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLKD 130 Query: 140 EELQEMID----EADRDGDGEVNEEEF 162 ++++ID EAD DG++++EE+ Sbjct: 131 TVIEDIIDKTFEEADTKHDGKIDKEEW 157 >6IIE-A nrPDB Length = 93 Score = 31.6 bits (70), Expect = 0.17, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 9/64 (14%) Query: 110 FRLFDDDETGKIS-------FKNLKRVANELGESLTDEE--LQEMIDEADRDGDGEVNEE 160 F+L+D D G + + RVA L +++ LQEM+ E D DG G V++ Sbjct: 15 FKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDGSGSVSQA 74 Query: 161 EFLK 164 E+++ Sbjct: 75 EWVR 78 >2LCP-A nrPDB Length = 190 Score = 30.8 bits (68), Expect = 0.28, Method: Compositional matrix adjust. Identities = 20/87 (22%), Positives = 36/87 (41%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 +G++ F + Q D + F +FD+++ G+I F + + D Sbjct: 39 PSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEFSEFIQALSVTSRGTLD 98 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIM 166 E+L+ D D DG + E L I+ Sbjct: 99 EKLRWAFKLYDLDNDGYITRNEMLDIV 125 >1KQV-A nrPDB Length = 79 Score = 30.4 bits (67), Expect = 0.37, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 22/29 (75%) Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 L E+ +E D++GDGEV+ EEF ++KK + Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKIS 78 >1RTP-1 nrPDB Length = 109 Score = 30.4 bits (67), Expect = 0.45, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDG 155 +K + +++ K F + D D++G I L + L+ +E + ++ D+DGDG Sbjct: 36 KKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDG 95 Query: 156 EVNEEEF 162 ++ EEF Sbjct: 96 KIGVEEF 102 Score = 29.6 bits (65), Expect = 0.70, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR---KEEMKKMISE 75 VG K + +D V++ F + D D SG I+ EL ++ + R +E K +++ Sbjct: 33 VGLKKKSADD----VKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAA 88 Query: 76 VDKEATGKISFNDFLAVMTQ 95 DK+ GKI +F ++ + Sbjct: 89 GDKDGDGKIGVEEFSTLVAE 108 >5VE9-A nrPDB Length = 91 Score = 30.0 bits (66), Expect = 0.47, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESL--TDEELQEMIDEADRDGDGEVNEE 160 K ++ FR D D+ GKI+ + + L T E+ + D DRDGDG ++ Sbjct: 26 KSRVMDFFRRIDKDQDGKITRQEF--IDGILASKFPTTKLEMTAVADIFDRDGDGYIDYY 83 Query: 161 EFLKIMK 167 EF+ + Sbjct: 84 EFVAALH 90 Score = 26.2 bits (56), Expect = 8.2, Method: Compositional matrix adjust. Identities = 12/29 (41%), Positives = 15/29 (51%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMR 58 K E+ D+FD DG G ID E A+ Sbjct: 62 KLEMTAVADIFDRDGDGYIDYYEFVAALH 90 >1BOD-A nrPDB Length = 74 Score = 30.0 bits (66), Expect = 0.49, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 22/29 (75%) Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 L E+ +E D++GDGEV+ EEF ++KK + Sbjct: 45 LDELFEELDKNGDGEVSFEEFQVLVKKIS 73 >2HPS-A nrPDB Length = 186 Score = 30.0 bits (66), Expect = 0.57, Method: Compositional matrix adjust. Identities = 15/57 (26%), Positives = 28/57 (49%) Query: 107 LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 L + D D+ G +S K +G LTD++ + D + +G+++ +EFL Sbjct: 105 LIMYDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFL 161 Score = 28.5 bits (62), Expect = 1.4, Method: Compositional matrix adjust. Identities = 14/57 (24%), Positives = 30/57 (52%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 +D D+D G + + E K ++A+G + ++ + +D G+IS ++FL + Sbjct: 108 YDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTV 164 >1G33-A nrPDB Length = 73 Score = 29.6 bits (65), Expect = 0.63, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR---KEEMKKMISEVDKEATGKISFND 88 +V++ F + D D SG I+ EL ++ + R +E K +++ DK+ GKI + Sbjct: 6 DVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEE 65 Query: 89 FLAVMTQ 95 F ++ + Sbjct: 66 FSTLVAE 72 Score = 29.3 bits (64), Expect = 0.90, Method: Compositional matrix adjust. Identities = 17/64 (26%), Positives = 33/64 (51%), Gaps = 3/64 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVN 158 + +++ K F + D D++G I L + L+ +E + ++ D+DGDG++ Sbjct: 3 SADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIG 62 Query: 159 EEEF 162 EEF Sbjct: 63 VEEF 66 >4NQG-A nrPDB Length = 197 Score = 29.6 bits (65), Expect = 0.64, Method: Compositional matrix adjust. Identities = 11/48 (22%), Positives = 23/48 (47%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 FD+ D DG+G++ + E G + + + + + D + GK+ Sbjct: 120 FDIIDKDGNGSVSLDEWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKL 167 >2NCO-A nrPDB Length = 102 Score = 29.6 bits (65), Expect = 0.69, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 35/83 (42%), Gaps = 10/83 (12%) Query: 14 SYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTID-------VKELKVAMRALGFEPRK 66 S K K P+ E D R F +D DGSG + +K+ M F P K Sbjct: 1 SSKPKYNPEVEAKLDV---ARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTK 57 Query: 67 EEMKKMISEVDKEATGKISFNDF 89 E++K + D + G +S ++ Sbjct: 58 EDVKIWLQMADTNSDGSVSLEEY 80 >5YPX-A nrPDB Length = 223 Score = 29.3 bits (64), Expect = 0.81, Method: Compositional matrix adjust. Identities = 23/89 (25%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Query: 83 KISFNDFLAVMTQKMAEKDTKEEIL--KAFRLFDDDETGKISFKNLKRVANELGESLTDE 140 K+ N F ++ QK + E++L + FR FD D IS + DE Sbjct: 61 KMDRNLFRDILHQKF---NMTEDLLMDRVFRAFDKDSDSYISLTEWVEGLSVFLRGTLDE 117 Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 +++ D +GDG ++ EE +++K Sbjct: 118 KMEYTFTVFDLNGDGYISREEMFQMLKTC 146 >4TR2-A nrPDB Length = 663 Score = 29.3 bits (64), Expect = 0.85, Method: Composition-based stats. Identities = 17/36 (47%), Positives = 22/36 (61%), Gaps = 1/36 (2%) Query: 119 GKIS-FKNLKRVANELGESLTDEELQEMIDEADRDG 153 GK+S KNLK + +L +TDEEL E I +R G Sbjct: 171 GKLSNLKNLKSMIIDLNSDMTDEELAEYISLLERKG 206 >2JTT-A nrPDB Length = 90 Score = 29.3 bits (64), Expect = 0.98, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 23/34 (67%) Query: 133 LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 +G L D E+ +++D+ DR+ D EVN +E++ + Sbjct: 44 IGSKLQDAEIVKLMDDLDRNKDQEVNFQEYITFL 77 >1CB1-A nrPDB Length = 78 Score = 28.9 bits (63), Expect = 1.2, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 21/29 (72%) Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 L ++ E D++GDGEV+ EEF ++KK + Sbjct: 49 LDDLFQELDKNGDGEVSFEEFQVLVKKIS 77 >1RK9-A nrPDB Length = 110 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/67 (25%), Positives = 35/67 (52%), Gaps = 3/67 (4%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDG 155 +K + +++ K F + D D++G I L + L+ +E + ++ D+DGDG Sbjct: 37 KKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDG 96 Query: 156 EVNEEEF 162 ++ +EF Sbjct: 97 KIGVDEF 103 >1NYA-A nrPDB Length = 176 Score = 28.1 bits (61), Expect = 2.2, Method: Compositional matrix adjust. Identities = 32/108 (29%), Positives = 49/108 (45%), Gaps = 18/108 (16%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDK 78 VG LTE+Q V E +L G + + R LG P +K ++ DK Sbjct: 69 VGSDGSLTEEQFIRVTE--NLIFEQGEASFN--------RVLG--PV---VKGIVGMCDK 113 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 A G+I+ ++F A +T A +K E +AF D + G++S L Sbjct: 114 NADGQINADEFAAWLT---ALGMSKAEAAEAFNQVDTNGNGELSLDEL 158 Score = 26.9 bits (58), Expect = 5.0, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 20/33 (60%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGF 62 K E EAF+ D++G+G + + EL A+R F Sbjct: 135 KAEAAEAFNQVDTNGNGELSLDELLTAVRDFHF 167 >2E6W-A nrPDB Length = 100 Score = 27.7 bits (60), Expect = 2.5, Method: Compositional matrix adjust. Identities = 21/79 (26%), Positives = 38/79 (48%), Gaps = 12/79 (15%) Query: 102 TKEEILKAFRLFDDDETGKIS----FKNLKRVANELG--------ESLTDEELQEMIDEA 149 E++ AF L+D ++ G I+ +K + + +G E E ++ ++ Sbjct: 7 VHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKM 66 Query: 150 DRDGDGEVNEEEFLKIMKK 168 DR+ DG V EEFL+ +K Sbjct: 67 DRNQDGVVTIEEFLEACQK 85 >2LVV-A nrPDB Length = 226 Score = 27.7 bits (60), Expect = 2.9, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKISFNDF- 89 E+ FD D DGS ++++E K A+ L + + + +E+D +G ++F++F Sbjct: 134 ELTVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDATTVFNEIDTNGSGVVTFDEFS 193 Query: 90 LAVMTQKM 97 +T+K+ Sbjct: 194 CWAVTKKL 201 >1KFU-L nrPDB Length = 699 Score = 27.3 bits (59), Expect = 3.2, Method: Compositional matrix adjust. Identities = 13/48 (27%), Positives = 27/48 (56%), Gaps = 6/48 (12%) Query: 38 DLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 D+ DSDGSG + +KE + + ++ +K+ E+D + +G ++ Sbjct: 581 DMLDSDGSGKLGLKEFYILWTKI------QKYQKIYREIDVDRSGTMN 622 Score = 26.2 bits (56), Expect = 7.0, Method: Compositional matrix adjust. Identities = 20/91 (21%), Positives = 44/91 (48%), Gaps = 8/91 (8%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 Q+ ++ + D D SGT++ E++ A+ GF+ + + +++ + I F++F+ Sbjct: 604 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKMPCQLHQVIVARFADDQL-IIDFDNFV 662 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 + + E + K F+ D + TG I Sbjct: 663 RCLVR-------LETLFKIFKQLDPENTGTI 686 >1JBA-A nrPDB Length = 204 Score = 27.3 bits (59), Expect = 3.2, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 48/114 (42%), Gaps = 16/114 (14%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 E+ Q V F FD++G TID E A+ + + ++K DK+ G I Sbjct: 54 NEEATQYVEAMFRAFDTNGDNTIDFLEYVAALNLVLRGTLEHKLKWTFKIYDKDRNGCID 113 Query: 86 FNDFL-----------AVMTQKMAEKD----TKEEIL-KAFRLFDDDETGKISF 123 + L A + AE+ T EE++ + F L D++ G++S Sbjct: 114 RQELLDIVESIYKLKKACSVEVEAEQQGKLLTPEEVVDRIFLLVDENGDGQLSL 167 >2Q4U-A nrPDB Length = 272 Score = 27.3 bits (59), Expect = 3.3, Method: Compositional matrix adjust. Identities = 17/63 (26%), Positives = 28/63 (44%), Gaps = 8/63 (12%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRK--------EEMKKMISEVDKEATGKISFNDFLA 91 +D+D SG I ELK ++ L + +K E M+ DK G++ ND Sbjct: 113 YDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLAR 172 Query: 92 VMT 94 ++ Sbjct: 173 ILA 175 >4YBH-B nrPDB Length = 92 Score = 27.3 bits (59), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 23/39 (58%) Query: 133 LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 +G L D E+ ++++ DR+ D EVN +E++ + L Sbjct: 46 IGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLGALAL 84 >4NSC-A nrPDB Length = 401 Score = 27.3 bits (59), Expect = 3.6, Method: Compositional matrix adjust. Identities = 14/49 (28%), Positives = 28/49 (57%), Gaps = 2/49 (4%) Query: 120 KISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 K++ + + R ++ L+D + D DG+GE++ +EF+ IMK+ Sbjct: 318 KVTMQQVARTVAKV--ELSDHVCDVVFALFDCDGNGELSNKEFVSIMKQ 364 >1SL8-A nrPDB Length = 191 Score = 27.3 bits (59), Expect = 3.7, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 +DK+ G IS +++ A T+ + E+ + FR+ D DE+G++ + R Sbjct: 118 IDKDQNGAISLDEWKA-YTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >2M7M-A nrPDB Length = 66 Score = 27.3 bits (59), Expect = 3.8, Method: Compositional matrix adjust. Identities = 15/55 (27%), Positives = 30/55 (54%) Query: 110 FRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 F+ D + G +S++ +K ++ ++ LQ + D DG+GE+++ EF K Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAK 60 >2MBX-A nrPDB Length = 109 Score = 27.3 bits (59), Expect = 3.9, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 33/69 (47%), Gaps = 3/69 (4%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVN 158 + +I K F + D D++ + LK +L+D E + + D DGDG++ Sbjct: 40 SPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSDAETKVFLKAGDSDGDGKIG 99 Query: 159 EEEFLKIMK 167 +EF ++K Sbjct: 100 VDEFGAMIK 108 >5N1Q-C nrPDB Length = 261 Score = 26.9 bits (58), Expect = 3.9, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 5/65 (7%) Query: 111 RLFDDDETGKISF--KNLKRVANE---LGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 R D++TG + + + R +E +GE L +E+L+E+ +DG ++EE L + Sbjct: 178 RYVYDEKTGHVVYVKDQVGRPLDEPVDVGEPLPEEKLREITTIYRKDGVPMRDDEELLTV 237 Query: 166 MKKTN 170 +K+ + Sbjct: 238 VKRIH 242 >5XOP-A nrPDB Length = 66 Score = 26.9 bits (58), Expect = 4.0, Method: Compositional matrix adjust. Identities = 16/56 (28%), Positives = 30/56 (53%) Query: 110 FRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 F+ D + G +S++ +K ++ ++ LQ + D+DGDG ++ EEF K Sbjct: 6 FKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 >3DF0-A nrPDB Length = 714 Score = 26.9 bits (58), Expect = 4.5, Method: Compositional matrix adjust. Identities = 27/112 (24%), Positives = 52/112 (46%), Gaps = 18/112 (16%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE-VDKEATGKISFNDF 89 Q+ ++ + D D SGT++ E++ A+ GF+ + + +++ D E I F++F Sbjct: 605 QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKLPCQLHQVIVARFADDELI--IDFDNF 662 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKI--------SFKNLKRVANEL 133 + + + E + K F+ D + TG I SF L ++A L Sbjct: 663 VRCLVR-------LEILFKIFKQLDPENTGTIQLDLISWLSFSVLGKLAAAL 707 >5CSF-A nrPDB Length = 95 Score = 26.6 bits (57), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/42 (35%), Positives = 25/42 (59%), Gaps = 4/42 (9%) Query: 129 VANELGESLTDEELQEMIDEA----DRDGDGEVNEEEFLKIM 166 + NEL L + + QE++D+ D DGDGE + +EF+ + Sbjct: 40 INNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFV 81 >6AGH-A nrPDB Length = 339 Score = 26.6 bits (57), Expect = 5.8, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 2/45 (4%) Query: 123 FKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 FK +VA G+ L++ L + D DGD ++ EEFL ++K Sbjct: 291 FKRAVKVAT--GQELSNNILDTVFKIFDLDGDECLSHEEFLGVLK 333 >1UHK-A nrPDB Length = 191 Score = 26.6 bits (57), Expect = 6.5, Method: Compositional matrix adjust. Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 1/53 (1%) Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 VDK+ G I+ +++ A T+ + E+ + FR+ D DE+G++ + R Sbjct: 118 VDKDQNGAITLDEWKA-YTKAAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 Score = 26.2 bits (56), Expect = 6.9, Method: Compositional matrix adjust. Identities = 13/48 (27%), Positives = 24/48 (50%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 FD+ D D +G I + E K +A G E+ ++ D + +G++ Sbjct: 115 FDIVDKDQNGAITLDEWKAYTKAAGIIQSSEDCEETFRVCDIDESGQL 162 >4OVR-A nrPDB Length = 322 Score = 26.6 bits (57), Expect = 6.6, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 25/43 (58%), Gaps = 2/43 (4%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEI 106 P + ++ M E++KE GKIS F +Q +EKDT E++ Sbjct: 37 PTVKAVQSMSDELNKETNGKISIKVFPN--SQLGSEKDTIEQV 77 >6MI5-X nrPDB Length = 117 Score = 26.2 bits (56), Expect = 7.9, Method: Compositional matrix adjust. Identities = 12/19 (63%), Positives = 13/19 (68%) Query: 36 AFDLFDSDGSGTIDVKELK 54 AFD D D GT+D KELK Sbjct: 32 AFDKLDPDKDGTLDAKELK 50 >2MA2-A nrPDB Length = 81 Score = 26.2 bits (56), Expect = 8.1, Method: Compositional matrix adjust. Identities = 12/34 (35%), Positives = 22/34 (64%), Gaps = 4/34 (11%) Query: 133 LGESLTDEELQEMIDEA----DRDGDGEVNEEEF 162 L ++L E +++M++ D DGDG +++EEF Sbjct: 2 LDQALVVEHIEKMVESVFRNFDVDGDGHISQEEF 35 >6EAZ-A nrPDB Length = 379 Score = 25.8 bits (55), Expect = 9.8, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 123 FKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 FK +VA G+ L+D L + D DGD ++ EFL ++K Sbjct: 294 FKRAVKVAT--GQELSDNLLDTVFKIFDLDGDECLSHGEFLGVLK 336 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4IL1-A nrPDB 208 1e-54 3EK4-A nrPDB 205 6e-54 4OY4-A nrPDB 205 9e-54 3U0K-A nrPDB 204 1e-53 5UKG-A nrPDB 201 1e-52 4I2Y-A nrPDB 198 9e-52 5D43-A nrPDB 189 6e-49 3WFN-B nrPDB 184 1e-47 2N6A-A nrPDB 183 4e-47 6O20-F nrPDB 179 5e-46 2F2P-A nrPDB 179 6e-46 2GGM-A nrPDB 176 4e-45 4E53-A nrPDB 176 4e-45 6HCS-A nrPDB 174 2e-44 1CLM-A nrPDB 171 1e-43 5I0I-E nrPDB 171 1e-43 5A2H-A nrPDB 168 1e-42 1GGZ-A nrPDB 168 1e-42 3QRX-A nrPDB 162 8e-41 2L1W-A nrPDB 158 1e-39 2LHI-A nrPDB 155 8e-39 3KF9-A nrPDB 152 6e-38 4DS7-A nrPDB 150 2e-37 2LMV-A nrPDB 150 4e-37 1LKJ-A nrPDB 148 1e-36 2OBH-A nrPDB 145 1e-35 3HZT-A nrPDB 142 9e-35 2TN4-A nrPDB 139 6e-34 1TOP-A nrPDB 139 6e-34 2LAP-A nrPDB 136 4e-33 3FWC-A nrPDB 135 7e-33 1W7I-B nrPDB 130 3e-31 3LIJ-A nrPDB 130 3e-31 2LC5-A nrPDB 129 6e-31 3KHE-A nrPDB 128 9e-31 3JAX-C nrPDB 128 9e-31 2LHH-A nrPDB 128 1e-30 5JN2-A nrPDB 127 3e-30 1DTL-A nrPDB 126 4e-30 3J04-B nrPDB 126 5e-30 2AAO-A nrPDB 126 5e-30 1S6I-A nrPDB 125 1e-29 3Q5I-A nrPDB 124 2e-29 4RGJ-A nrPDB 124 2e-29 4MVF-A nrPDB 123 4e-29 6FSA-D nrPDB 122 6e-29 3DTP-E nrPDB 122 7e-29 3L19-A nrPDB 121 1e-28 2M29-A nrPDB 121 2e-28 5H53-C nrPDB 121 2e-28 5TBY-C nrPDB 121 2e-28 4WPX-A nrPDB 120 3e-28 4YZB-A nrPDB 118 9e-28 2BL0-B nrPDB 118 1e-27 5ZOR-A nrPDB 117 2e-27 3PM8-A nrPDB 117 2e-27 2OS8-B nrPDB 116 5e-27 3NCG-A nrPDB 116 6e-27 5TBY-E nrPDB 115 9e-27 2W4G-C nrPDB 115 2e-26 2JNF-A nrPDB 114 2e-26 5E37-A nrPDB 112 6e-26 2BL0-C nrPDB 112 6e-26 1B7T-Y nrPDB 112 8e-26 1SR6-C nrPDB 112 9e-26 1I84-U nrPDB 110 3e-25 3TS5-B nrPDB 110 5e-25 1GGW-A nrPDB 110 5e-25 1O1A-B nrPDB 109 6e-25 3I5H-B nrPDB 109 8e-25 4ORC-B nrPDB 108 1e-24 5H53-B nrPDB 108 2e-24 3JBH-C nrPDB 106 5e-24 1DFK-Y nrPDB 105 1e-23 1ZMZ-A nrPDB 105 2e-23 4JWQ-A nrPDB 104 2e-23 3O4Y-A nrPDB 103 3e-23 3K21-A nrPDB 103 5e-23 2EC6-B nrPDB 103 6e-23 3IFK-A nrPDB 100 3e-22 5B7X-A nrPDB 99 1e-21 3I5I-C nrPDB 98 1e-21 5B8I-B nrPDB 98 1e-21 1N2D-A nrPDB 97 3e-21 1Y1X-A nrPDB 97 5e-21 5H7D-E nrPDB 96 9e-21 4N5X-A nrPDB 95 1e-20 4ZCV-A nrPDB 95 1e-20 1SJJ-A nrPDB 95 1e-20 2AMI-A nrPDB 94 4e-20 5COC-A nrPDB 93 4e-20 4OCI-A nrPDB 93 4e-20 2I08-A nrPDB 93 5e-20 4D1E-A nrPDB 93 7e-20 2RO8-A nrPDB 92 1e-19 5W1A-B nrPDB 90 6e-19 1M39-A nrPDB 89 9e-19 3AAJ-A nrPDB 89 1e-18 2BEC-A nrPDB 88 1e-18 2LV7-A nrPDB 87 4e-18 4Q57-A nrPDB 86 6e-18 1FW4-A nrPDB 86 9e-18 2N8Y-A nrPDB 85 1e-17 2KN2-A nrPDB 85 1e-17 1F55-A nrPDB 84 2e-17 2KZ2-A nrPDB 83 5e-17 5VLN-A nrPDB 83 7e-17 2M5E-A nrPDB 82 9e-17 2KSZ-A nrPDB 82 1e-16 5MWC-D nrPDB 82 1e-16 2RO9-A nrPDB 81 2e-16 2E30-A nrPDB 81 2e-16 2N7L-C nrPDB 81 3e-16 2ROB-A nrPDB 80 4e-16 5Z1Q-A nrPDB 80 4e-16 1TNP-A nrPDB 80 5e-16 1TRF-A nrPDB 79 8e-16 3E3R-A nrPDB 79 9e-16 2R2I-A nrPDB 79 1e-15 2B1U-A nrPDB 79 1e-15 2HF5-A nrPDB 78 2e-15 2K2I-A nrPDB 78 2e-15 4GJF-A nrPDB 77 5e-15 2JOJ-A nrPDB 76 6e-15 1OQP-A nrPDB 75 1e-14 1JUO-A nrPDB 75 2e-14 2K7B-A nrPDB 73 4e-14 5MRA-A nrPDB 73 5e-14 1JF0-A nrPDB 72 1e-13 2M8U-A nrPDB 71 2e-13 3H4S-E nrPDB 71 3e-13 1GJY-A nrPDB 71 3e-13 5T7C-A nrPDB 70 5e-13 1BJF-A nrPDB 70 6e-13 1F4Q-A nrPDB 70 6e-13 1S36-A nrPDB 69 8e-13 2K7C-A nrPDB 68 1e-12 5I2L-A nrPDB 68 1e-12 3KPX-A nrPDB 68 2e-12 2AUC-A nrPDB 68 2e-12 2I94-A nrPDB 68 2e-12 2G9B-A nrPDB 68 2e-12 4AOM-A nrPDB 67 3e-12 1KFX-S nrPDB 67 3e-12 1JC2-A nrPDB 67 4e-12 5OTJ-D nrPDB 67 4e-12 2M97-A nrPDB 67 5e-12 1QXP-A nrPDB 67 5e-12 3BOW-B nrPDB 66 1e-11 3TZ1-A nrPDB 65 1e-11 2K2A-A nrPDB 65 1e-11 1DGU-A nrPDB 65 2e-11 1S6J-A nrPDB 64 3e-11 2LM5-A nrPDB 64 3e-11 1C7W-A nrPDB 64 4e-11 2LVK-A nrPDB 63 4e-11 1H4B-A nrPDB 63 4e-11 1OZS-A nrPDB 63 5e-11 2OPO-A nrPDB 63 8e-11 2FCE-A nrPDB 62 2e-10 2VTG-A nrPDB 60 4e-10 2G2B-A nrPDB 60 6e-10 1QX2-A nrPDB 58 2e-09 1WY9-A nrPDB 57 3e-09 2D58-A nrPDB 56 8e-09 3PAT-A nrPDB 54 3e-08 1TIZ-A nrPDB 54 3e-08 Sequences not found previously or not previously below threshold: 2NA0-A nrPDB 74 3e-14 2GGZ-A nrPDB 70 5e-13 2JNX-A nrPDB 68 1e-12 1JBA-A nrPDB 68 2e-12 1JFJ-A nrPDB 66 8e-12 5M6C-E nrPDB 65 2e-11 1V1G-A nrPDB 65 2e-11 2JUL-A nrPDB 64 2e-11 2JU0-A nrPDB 64 3e-11 3SIA-A nrPDB 64 3e-11 3AKA-A nrPDB 64 4e-11 2L2E-A nrPDB 62 1e-10 2Q4U-A nrPDB 62 2e-10 2D8N-A nrPDB 61 2e-10 2ZFD-A nrPDB 60 4e-10 3MSE-B nrPDB 60 4e-10 4OKH-A nrPDB 60 4e-10 5XND-A nrPDB 60 5e-10 1UHN-A nrPDB 58 2e-09 5VT9-A nrPDB 58 2e-09 2LCP-A nrPDB 58 2e-09 3DD4-A nrPDB 57 4e-09 1NYA-A nrPDB 57 5e-09 5ZGM-A nrPDB 57 6e-09 2M7L-A nrPDB 57 6e-09 2M1U-A nrPDB 56 7e-09 1NP8-A nrPDB 56 1e-08 1IJ5-A nrPDB 56 1e-08 5PAL-A nrPDB 56 1e-08 1KFU-L nrPDB 55 2e-08 3DF0-A nrPDB 55 2e-08 6EPA-A nrPDB 55 2e-08 3CS1-A nrPDB 54 3e-08 2LVV-A nrPDB 54 3e-08 1S6C-A nrPDB 54 4e-08 4PAL-A nrPDB 54 4e-08 1A75-A nrPDB 54 4e-08 1SL8-A nrPDB 53 6e-08 1S1E-A nrPDB 53 6e-08 5JOJ-A nrPDB 53 7e-08 2KQY-A nrPDB 53 7e-08 5JOL-A nrPDB 53 9e-08 5VE9-A nrPDB 52 1e-07 2HPS-A nrPDB 52 1e-07 1UHK-A nrPDB 52 2e-07 1BU3-A nrPDB 51 2e-07 5CPV-A nrPDB 51 2e-07 4NQG-A nrPDB 51 2e-07 2KYF-A nrPDB 51 3e-07 1RTP-1 nrPDB 50 7e-07 5ZH6-A nrPDB 50 7e-07 1RK9-A nrPDB 49 9e-07 2MBX-A nrPDB 49 1e-06 2NLN-A nrPDB 48 1e-06 5YPX-A nrPDB 48 1e-06 1Q80-A nrPDB 48 2e-06 1TTX-A nrPDB 48 2e-06 4P5W-A nrPDB 48 3e-06 1YX7-A nrPDB 47 3e-06 4P5X-A nrPDB 47 3e-06 5E1J-A nrPDB 47 3e-06 1G33-A nrPDB 47 4e-06 4GFT-A nrPDB 46 5e-06 2PMY-A nrPDB 46 7e-06 5XOP-A nrPDB 45 2e-05 2E6W-A nrPDB 44 3e-05 6AGI-A nrPDB 44 4e-05 5CUY-A nrPDB 44 4e-05 1CB1-A nrPDB 42 1e-04 2NCO-A nrPDB 42 2e-04 2M7M-A nrPDB 41 3e-04 1ZFS-A nrPDB 41 3e-04 5CUU-A nrPDB 40 4e-04 6MI5-X nrPDB 40 4e-04 4MEW-A nrPDB 40 6e-04 5C5V-A nrPDB 40 7e-04 1BOD-A nrPDB 40 7e-04 6IIE-A nrPDB 39 0.001 5MKE-A nrPDB 39 0.001 6D1W-A nrPDB 39 0.001 1NSH-A nrPDB 38 0.001 4YBH-B nrPDB 38 0.002 2L0P-A nrPDB 38 0.003 1QLS-A nrPDB 37 0.003 4I5K-A nrPDB 37 0.004 2I18-A nrPDB 37 0.004 3LCP-C nrPDB 36 0.006 2VRG-A nrPDB 36 0.006 2LUC-A nrPDB 36 0.007 2KGR-A nrPDB 36 0.007 3A4U-B nrPDB 36 0.008 4I5L-B nrPDB 36 0.009 2JTT-A nrPDB 36 0.010 4YGB-B nrPDB 36 0.011 5X2E-A nrPDB 36 0.011 4L9M-A nrPDB 35 0.013 6DU8-A nrPDB 35 0.014 4C0K-A nrPDB 35 0.014 1J7Q-A nrPDB 35 0.015 1KQV-A nrPDB 35 0.017 1DJX-A nrPDB 35 0.017 2MA2-A nrPDB 35 0.019 5VP3-A nrPDB 34 0.037 1C07-A nrPDB 34 0.044 5KU1-A nrPDB 33 0.056 3A8R-A nrPDB 33 0.061 4MSP-A nrPDB 33 0.062 6EAZ-A nrPDB 33 0.066 2SAS-A nrPDB 33 0.066 2MHH-A nrPDB 33 0.066 2WCE-A nrPDB 33 0.073 1B4A-A nrPDB 33 0.078 4HRG-A nrPDB 33 0.083 4NSC-A nrPDB 32 0.10 3NSO-A nrPDB 32 0.12 3JC6-4 nrPDB 32 0.14 6AGH-A nrPDB 32 0.14 4MN0-A nrPDB 32 0.16 4FTG-A nrPDB 32 0.16 5CJ9-A nrPDB 32 0.17 5CSF-A nrPDB 31 0.18 2KLD-A nrPDB 31 0.18 5LPU-C nrPDB 31 0.19 2KHN-A nrPDB 31 0.19 5NRM-B nrPDB 31 0.22 2MJW-B nrPDB 31 0.23 5HYD-A nrPDB 31 0.25 2L50-A nrPDB 31 0.28 5HLO-A nrPDB 31 0.28 1XDL-A nrPDB 31 0.28 4CFQ-A nrPDB 31 0.29 4DUQ-A nrPDB 31 0.31 2JXC-A nrPDB 30 0.40 6DS2-B nrPDB 30 0.41 2KQ6-A nrPDB 30 0.41 1IQ3-A nrPDB 30 0.42 2Y5I-A nrPDB 30 0.46 1SP9-A nrPDB 30 0.51 1WLM-A nrPDB 30 0.71 2KFH-A nrPDB 30 0.71 2JQ6-A nrPDB 30 0.80 6EFR-A nrPDB 30 0.82 5NRK-B nrPDB 30 0.84 1FI6-A nrPDB 30 0.84 5GAH-J nrPDB 29 1.0 4EMZ-A nrPDB 29 1.2 2QPT-A nrPDB 29 1.2 2JRF-A nrPDB 29 1.2 3VSL-A nrPDB 29 1.2 5DXI-A nrPDB 29 1.3 5R1R-A nrPDB 29 1.3 2KAY-A nrPDB 29 1.3 4WSI-A nrPDB 29 1.3 6BVD-A nrPDB 28 1.6 2I7A-A nrPDB 28 2.0 6D84-M nrPDB 28 2.1 6BY1-CI nrPDB 28 2.1 4QIW-A nrPDB 28 2.5 3J09-A nrPDB 28 3.2 6G18-t nrPDB 27 3.5 5MVF-A nrPDB 27 4.2 2DI4-A nrPDB 27 4.2 2Z61-A nrPDB 27 4.7 1QJT-A nrPDB 27 5.0 1SC5-A nrPDB 27 5.2 3J3U-A nrPDB 27 5.4 3PXG-A nrPDB 26 5.6 5W62-A nrPDB 26 6.3 3PXI-A nrPDB 26 6.5 6FFL-A nrPDB 26 6.6 4JB3-A nrPDB 26 7.3 4Z7E-A nrPDB 26 7.6 2V2V-A nrPDB 26 7.9 2GLF-A nrPDB 26 8.0 4Z8X-A nrPDB 26 8.4 1QS1-A nrPDB 26 8.4 2Y3N-B nrPDB 26 8.6 1QS2-A nrPDB 26 8.7 3NA5-A nrPDB 26 9.6 >4IL1-A nrPDB Length = 823 Score = 208 bits (529), Expect = 1e-54, Method: Composition-based stats. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMM 146 Score = 120 bits (301), Expect = 3e-28, Method: Composition-based stats. Identities = 42/155 (27%), Positives = 87/155 (56%), Gaps = 9/155 (5%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 D+ + + + F D D SG++ V+E +++ L P ++++I D + G Sbjct: 170 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNG 225 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEE 141 ++ F +F+ ++Q + D ++++ AFR++D D+ G IS L +V + G +L D + Sbjct: 226 EVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 285 Query: 142 LQEMIDE----ADRDGDGEVNEEEFLKIMKKTNLY 172 LQ+++D+ AD+DGDG ++ EEF ++ +++ Sbjct: 286 LQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 320 Score = 114 bits (286), Expect = 2e-26, Method: Composition-based stats. Identities = 50/194 (25%), Positives = 91/194 (46%), Gaps = 27/194 (13%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 111 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ------------------KMAEK 100 LG + EE+ +MI E D + G++++ +F+ +MT +M Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGGGGGGNEASYPLEMCSH 171 Query: 101 DTKEEIL---KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEV 157 +EI K F+ D D +G +S + EL ++ +Q +ID D DG+GEV Sbjct: 172 FDADEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNGEV 227 Query: 158 NEEEFLKIMKKTNL 171 + +EF++ + + ++ Sbjct: 228 DFKEFIEGVSQFSV 241 Score = 90.8 bits (224), Expect = 3e-19, Method: Composition-based stats. Identities = 31/78 (39%), Positives = 46/78 (58%), Gaps = 1/78 (1%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 M ++ E+ E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D D Sbjct: 1 MADQLTEEQI-AEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD 59 Query: 153 GDGEVNEEEFLKIMKKTN 170 G+G ++ EFL +M + Sbjct: 60 GNGTIDFPEFLTMMARKM 77 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELT--EDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 + F +K + + + D++Q++R AF ++D D G I EL ++ Sbjct: 215 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 274 Query: 59 AL-GFEPRKEEMKKMISEV----DKEATGKISFNDFLAVMTQKMAEKDT 102 + G + ++++++ + DK+ G+ISF +F AV+ K Sbjct: 275 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKM 323 >3EK4-A nrPDB Length = 451 Score = 205 bits (523), Expect = 6e-54, Method: Composition-based stats. Identities = 78/153 (50%), Positives = 104/153 (67%) Query: 14 SYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMI 73 +K + + +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI Sbjct: 296 GHKLEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMI 355 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 +EVD + G I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V L Sbjct: 356 NEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNL 415 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 GE LTDEE+ EMI EAD DGDG+VN EEF+++M Sbjct: 416 GEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 448 Score = 89.6 bits (221), Expect = 6e-19, Method: Composition-based stats. Identities = 31/81 (38%), Positives = 46/81 (56%) Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 L T+ ++ E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E Sbjct: 299 LEYNTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEV 358 Query: 150 DRDGDGEVNEEEFLKIMKKTN 170 D DG+G ++ EFL +M + Sbjct: 359 DADGNGTIDFPEFLTMMARKM 379 Score = 85.0 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 354 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 413 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+ +MI E D + G++++ +F+ +MT Sbjct: 414 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 449 >4OY4-A nrPDB Length = 415 Score = 205 bits (521), Expect = 9e-54, Method: Composition-based stats. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 11 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGT 70 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 130 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 131 EMIREADIDGDGQVNYEEFVQMM 153 Score = 90.4 bits (223), Expect = 3e-19, Method: Composition-based stats. Identities = 30/66 (45%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DGDG ++ EFL Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTIDFPEFLT 78 Query: 165 IMKKTN 170 +M + Sbjct: 79 MMARKM 84 Score = 86.6 bits (213), Expect = 6e-18, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 53/104 (50%), Gaps = 2/104 (1%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 59 MINEVDADGDGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 118 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDT 102 LG + EE+ +MI E D + G++++ +F+ +MT K+ + Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKLECEKM 162 >3U0K-A nrPDB Length = 442 Score = 204 bits (520), Expect = 1e-53, Method: Composition-based stats. Identities = 79/157 (50%), Positives = 103/157 (65%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEM 69 V K + +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E+ Sbjct: 283 VMQKKTKGWEPTRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAEL 342 Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + MI+EVD + G I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V Sbjct: 343 QDMINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHV 402 Query: 130 ANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 LGE LTDEE+ EMI EAD DGDG+VN EEF+++M Sbjct: 403 MTNLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMM 439 Score = 90.4 bits (223), Expect = 3e-19, Method: Composition-based stats. Identities = 31/77 (40%), Positives = 45/77 (58%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 T+ ++ E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 294 TRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 353 Query: 154 DGEVNEEEFLKIMKKTN 170 DG ++ EFL +M + Sbjct: 354 DGTIDFPEFLIMMARKM 370 Score = 85.8 bits (211), Expect = 9e-18, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 345 MINEVDADGDGTIDFPEFLIMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 404 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+ +MI E D + G++++ +F+ +MT Sbjct: 405 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 440 >5UKG-A nrPDB Length = 419 Score = 201 bits (512), Expect = 1e-52, Method: Composition-based stats. Identities = 74/149 (49%), Positives = 98/149 (65%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD 77 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD Sbjct: 268 WEASNGQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD 327 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 + G F +FL +M +KM+ + T+EEI +AFR+FD D G I L+ V +LGE L Sbjct: 328 ADGDGTFDFPEFLTMMARKMSYRVTEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKL 387 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIM 166 TDEE+ EMI AD DGDG+VN EEF+++M Sbjct: 388 TDEEVDEMIRVADIDGDGQVNYEEFVQMM 416 Score = 91.9 bits (227), Expect = 1e-19, Method: Composition-based stats. Identities = 31/68 (45%), Positives = 41/68 (60%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DGDG + EFL Sbjct: 282 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGDGTFDFPEFLT 341 Query: 165 IMKKTNLY 172 +M + Y Sbjct: 342 MMARKMSY 349 Score = 80.0 bits (196), Expect = 4e-16, Method: Composition-based stats. Identities = 25/65 (38%), Positives = 42/65 (64%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI D + G++++ +F Sbjct: 353 EEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYEEF 412 Query: 90 LAVMT 94 + +MT Sbjct: 413 VQMMT 417 >4I2Y-A nrPDB Length = 421 Score = 198 bits (504), Expect = 9e-52, Method: Composition-based stats. Identities = 74/149 (49%), Positives = 99/149 (66%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD 77 + +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD Sbjct: 270 WEATRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVD 329 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 + G F +FL +M +KM + D++EEI +AFR+FD D G I L+ V +LGE L Sbjct: 330 ADGDGTFDFPEFLTMMARKMNDTDSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKL 389 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIM 166 TDEE+ EMI AD DGDG+VN EEF+++M Sbjct: 390 TDEEVDEMIRVADIDGDGQVNYEEFVQMM 418 Score = 89.2 bits (220), Expect = 9e-19, Method: Composition-based stats. Identities = 31/78 (39%), Positives = 44/78 (56%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 T+ ++ E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG Sbjct: 273 TRDQLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADG 332 Query: 154 DGEVNEEEFLKIMKKTNL 171 DG + EFL +M + Sbjct: 333 DGTFDFPEFLTMMARKMN 350 Score = 80.0 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 26/67 (38%), Positives = 43/67 (64%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI D + G++++ Sbjct: 353 DSEEEIREAFRVFDKDGNGYIGAAELRHVMTDLGEKLTDEEVDEMIRVADIDGDGQVNYE 412 Query: 88 DFLAVMT 94 +F+ +MT Sbjct: 413 EFVQMMT 419 >5D43-A nrPDB Length = 178 Score = 189 bits (480), Expect = 6e-49, Method: Composition-based stats. Identities = 172/172 (100%), Positives = 172/172 (100%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL Sbjct: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK Sbjct: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY Sbjct: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 >3WFN-B nrPDB Length = 182 Score = 184 bits (468), Expect = 1e-47, Method: Composition-based stats. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 10 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 69 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 70 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 129 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 130 EMIREADIDGDGQVNYEEFVQMM 152 Score = 80.8 bits (198), Expect = 3e-16, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 18 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 77 Query: 165 IMKKTN 170 +M + Sbjct: 78 MMARKM 83 Score = 77.3 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 29/105 (27%), Positives = 52/105 (49%), Gaps = 2/105 (1%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 58 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 117 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 LG + EE+ +MI E D + G++++ +F+ +MT K + Sbjct: 118 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGEE 162 >2N6A-A nrPDB Length = 173 Score = 183 bits (464), Expect = 4e-47, Method: Composition-based stats. Identities = 76/145 (52%), Positives = 99/145 (68%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 TE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I Sbjct: 7 TEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTID 66 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ EM Sbjct: 67 FPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEM 126 Query: 146 IDEADRDGDGEVNEEEFLKIMKKTN 170 I EAD DGDG+VN EEF+++M + Sbjct: 127 IREADIDGDGQVNYEEFVQMMTGAS 151 >6O20-F nrPDB Length = 169 Score = 179 bits (455), Expect = 5e-46, Method: Composition-based stats. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 24 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 83 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 84 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 143 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 144 EMIREADIDGDGQVNYEEFVQMM 166 Score = 78.8 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 32 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 91 Query: 165 IMKKTN 170 +M + Sbjct: 92 MMARKM 97 Score = 75.0 bits (183), Expect = 2e-14, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 72 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 131 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+ +MI E D + G++++ +F+ +MT Sbjct: 132 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 167 >2F2P-A nrPDB Length = 179 Score = 179 bits (454), Expect = 6e-46, Method: Composition-based stats. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMM 146 Score = 78.5 bits (192), Expect = 1e-15, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 71 Query: 165 IMKKTN 170 +M + Sbjct: 72 MMARKM 77 Score = 75.0 bits (183), Expect = 2e-14, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 111 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+ +MI E D + G++++ +F+ +MT Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147 >2GGM-A nrPDB Length = 172 Score = 176 bits (447), Expect = 4e-45, Method: Composition-based stats. Identities = 141/172 (81%), Positives = 165/172 (95%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 MAS F+K+N+AS+S ++++ PKPELTE+QKQE+REAFDLFD+DG+GTIDVKELKVAMRAL Sbjct: 1 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL 60 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GFEP+KEE+KKMISE+DKE TGK++F DFL VMTQKM+EKDTKEEILKAF+LFDDDETGK Sbjct: 61 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGK 120 Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 ISFKNLKRVA ELGE+LTDEELQEMIDEADRDGDGEV+E+EFL+IMKKT+LY Sbjct: 121 ISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKKTSLY 172 >4E53-A nrPDB Length = 185 Score = 176 bits (447), Expect = 4e-45, Method: Composition-based stats. Identities = 77/143 (53%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 11 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 70 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 71 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 130 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 131 EMIREADIDGDGQVNYEEFVQMM 153 Score = 78.5 bits (192), Expect = 1e-15, Method: Composition-based stats. Identities = 37/129 (28%), Positives = 62/129 (48%), Gaps = 9/129 (6%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 59 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 118 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDET 118 LG + EE+ +MI E D + G++++ +F+ +MT K +I +FR Sbjct: 119 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMTAKGGGGGAATKIQASFR------- 171 Query: 119 GKISFKNLK 127 G I+ K LK Sbjct: 172 GHITRKKLK 180 Score = 77.3 bits (189), Expect = 3e-15, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 19 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 78 Query: 165 IMKKTN 170 +M + Sbjct: 79 MMARKM 84 >6HCS-A nrPDB Length = 167 Score = 174 bits (441), Expect = 2e-44, Method: Composition-based stats. Identities = 76/143 (53%), Positives = 99/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ LGE LTDEE+ Sbjct: 64 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 124 EMIREADIDGDGQVNYEEFVQMM 146 Score = 76.9 bits (188), Expect = 4e-15, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 12 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 71 Query: 165 IMKKTN 170 +M + Sbjct: 72 MMARKM 77 Score = 72.7 bits (177), Expect = 8e-14, Method: Composition-based stats. Identities = 28/96 (29%), Positives = 50/96 (52%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 52 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHFMT 111 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+ +MI E D + G++++ +F+ +MT Sbjct: 112 NLGEKLTDEEVDEMIREADIDGDGQVNYEEFVQMMT 147 >1CLM-A nrPDB Length = 148 Score = 171 bits (434), Expect = 1e-43, Method: Composition-based stats. Identities = 75/144 (52%), Positives = 102/144 (70%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ELTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 ELTEEQIAEFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL++M +KM E+D++EE+++AF++FD D G IS L+ V LGE LTD+E+ Sbjct: 63 IDFPEFLSLMARKMKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVD 122 Query: 144 EMIDEADRDGDGEVNEEEFLKIMK 167 EMI EAD DGDG +N EEF+++M Sbjct: 123 EMIREADIDGDGHINYEEFVRMMV 146 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 11 EFKEAFALFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLS 70 Query: 165 IMKKTN 170 +M + Sbjct: 71 LMARKM 76 >5I0I-E nrPDB Length = 145 Score = 171 bits (433), Expect = 1e-43, Method: Composition-based stats. Identities = 76/143 (53%), Positives = 99/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF L D DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 2 QLTEEQIAEFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 61 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ Sbjct: 62 IDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVD 121 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG+VN EEF+++M Sbjct: 122 EMIREADIDGDGQVNYEEFVQMM 144 Score = 73.5 bits (179), Expect = 4e-14, Method: Composition-based stats. Identities = 28/66 (42%), Positives = 40/66 (60%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF L D D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 10 EFKEAFSLADKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 69 Query: 165 IMKKTN 170 +M + Sbjct: 70 MMARKM 75 Score = 72.7 bits (177), Expect = 8e-14, Method: Composition-based stats. Identities = 27/67 (40%), Positives = 44/67 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 79 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 138 Query: 88 DFLAVMT 94 +F+ +MT Sbjct: 139 EFVQMMT 145 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 48/105 (45%), Gaps = 2/105 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E K+ S DK+ G I+ + VM + + + T+ E+ D D G I F Sbjct: 9 AEFKEAFSLADKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEF 67 Query: 127 KRVA-NELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 + ++ ++ ++EE++E D+DG+G ++ E +M Sbjct: 68 LTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 112 >5A2H-A nrPDB Length = 149 Score = 168 bits (425), Expect = 1e-42, Method: Composition-based stats. Identities = 75/143 (52%), Positives = 100/143 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LT+DQ E +EAF LFD DG G I KEL MR+LG P + E++ MI+EVD + G Sbjct: 4 QLTDDQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 63 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I F +FL +M +KM + D++EE+ +AFR+FD D+ G IS L+ V LGE LTDEE+ Sbjct: 64 IDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVD 123 Query: 144 EMIDEADRDGDGEVNEEEFLKIM 166 EMI EAD DGDG++N EEF+K+M Sbjct: 124 EMIREADVDGDGQINYEEFVKVM 146 Score = 74.6 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 29/67 (43%), Positives = 41/67 (61%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 11 SEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 70 Query: 164 KIMKKTN 170 +M + Sbjct: 71 NLMARKM 77 Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 27/96 (28%), Positives = 48/96 (50%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRKVG--PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E++EAF +FD D +G I EL+ M Sbjct: 52 MINEVDADGNGTIDFPEFLNLMARKMKDTDSEEELKEAFRVFDKDQNGFISAAELRHVMT 111 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+ +MI E D + G+I++ +F+ VM Sbjct: 112 NLGEKLTDEEVDEMIREADVDGDGQINYEEFVKVMM 147 >1GGZ-A nrPDB Length = 148 Score = 168 bits (425), Expect = 1e-42, Method: Composition-based stats. Identities = 69/144 (47%), Positives = 98/144 (68%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG G I +EL MR+LG P + E++ M+SE+D++ G Sbjct: 3 QLTEEQVTEFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 + F +FL +M +KM + D +EEI +AFR+FD D G +S L+ V LGE L+DEE+ Sbjct: 63 VDFPEFLGMMARKMKDTDNEEEIREAFRVFDKDGNGFVSAAELRHVMTRLGEKLSDEEVD 122 Query: 144 EMIDEADRDGDGEVNEEEFLKIMK 167 EMI AD DGDG+VN EEF++++ Sbjct: 123 EMIRAADTDGDGQVNYEEFVRVLV 146 Score = 76.5 bits (187), Expect = 5e-15, Method: Composition-based stats. Identities = 28/66 (42%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ + L V LG++ T+ EL++M+ E DRDG+G V+ EFL Sbjct: 11 EFKEAFSLFDKDGDGCITTRELGTVMRSLGQNPTEAELRDMMSEIDRDGNGTVDFPEFLG 70 Query: 165 IMKKTN 170 +M + Sbjct: 71 MMARKM 76 >3QRX-A nrPDB Length = 169 Score = 162 bits (410), Expect = 8e-41, Method: Composition-based stats. Identities = 110/169 (65%), Positives = 142/169 (84%), Gaps = 1/169 (0%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 +++ V S +K G + LTE+QKQE+REAFDLFD+DGSGTID KELKVAMRALGFE Sbjct: 2 SYKAKTVVSARRDQKKG-RVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 60 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 P+KEE+KKMISE+DK+ +G I F +FL +MT KM E+D++EEILKAFRLFDDD +G I+ Sbjct: 61 PKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKMGERDSREEILKAFRLFDDDNSGTITI 120 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 K+L+RVA ELGE+LT+EELQEMI EADR+ D E++E+EF++IMKKT+L+ Sbjct: 121 KDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDEDEFIRIMKKTSLF 169 >2L1W-A nrPDB Length = 149 Score = 158 bits (399), Expect = 1e-39, Method: Composition-based stats. Identities = 71/142 (50%), Positives = 102/142 (71%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+Q + +EAF LFD DG G I V+EL +R+L P +EE++ MISEVD + G I Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F++FL++M +K+ + D +EE+ +AF++FD D+ G IS L+ V LGE LTDEE+++ Sbjct: 64 EFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQ 123 Query: 145 MIDEADRDGDGEVNEEEFLKIM 166 MI EAD DGDG+VN EEF+K+M Sbjct: 124 MIKEADLDGDGQVNYEEFVKMM 145 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 27/96 (28%), Positives = 49/96 (51%), Gaps = 2/96 (2%) Query: 1 MASTFRKSNVASTSYKRKVG--PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M S + + + K D ++E++EAF +FD D +G I EL+ M Sbjct: 51 MISEVDADGNGTIEFDEFLSLMAKKVKDTDAEEELKEAFKVFDKDQNGYISASELRHVMI 110 Query: 59 ALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 LG + EE+++MI E D + G++++ +F+ +M Sbjct: 111 NLGEKLTDEEVEQMIKEADLDGDGQVNYEEFVKMMM 146 Score = 70.4 bits (171), Expect = 4e-13, Method: Composition-based stats. Identities = 28/64 (43%), Positives = 40/64 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + +AF LFD D G I+ + L V L ++ T+EELQ+MI E D DG+G + +EFL Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLS 70 Query: 165 IMKK 168 +M K Sbjct: 71 LMAK 74 >2LHI-A nrPDB Length = 176 Score = 155 bits (393), Expect = 8e-39, Method: Composition-based stats. Identities = 58/148 (39%), Positives = 96/148 (64%), Gaps = 1/148 (0%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + Sbjct: 3 SNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNH 62 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEEL 142 +I F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD E+ Sbjct: 63 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEV 122 Query: 143 QEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +M+ E DG GE+N ++F ++ K + Sbjct: 123 DDMLREV-SDGSGEINIQQFAALLSKGS 149 Score = 68.8 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 46/83 (55%), Gaps = 1/83 (1%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 + D +QE+ EAF +FD +G G I ELK + ++G + E+ M+ EV + +G+I+ Sbjct: 79 SNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDDMLREV-SDGSGEIN 137 Query: 86 FNDFLAVMTQKMAEKDTKEEILK 108 F A++++ + ++ + Sbjct: 138 IQQFAALLSKGSSTGTRRKALRN 160 Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 136 SLTDE---ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 +LT+E E +E D+D +G ++ E +M+ L Sbjct: 4 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGL 42 >3KF9-A nrPDB Length = 149 Score = 152 bits (385), Expect = 6e-38, Method: Composition-based stats. Identities = 117/148 (79%), Positives = 138/148 (93%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+QKQE+REAFDLFD+DGSGTID KELKVAMRALGFEP+KEE+KKMI+++DK+ +G I Sbjct: 2 LTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMIADIDKDGSGTI 61 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F +FL +MT KM E+D++EEI+KAFRLFDDDETGKISFKNLKRVA ELGE++TDEELQE Sbjct: 62 DFEEFLQMMTAKMGERDSREEIMKAFRLFDDDETGKISFKNLKRVAKELGENMTDEELQE 121 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKTNLY 172 MIDEADRDGDGEVNEEEF +IMKKT+L+ Sbjct: 122 MIDEADRDGDGEVNEEEFFRIMKKTSLF 149 >4DS7-A nrPDB Length = 147 Score = 150 bits (380), Expect = 2e-37, Method: Composition-based stats. Identities = 60/144 (41%), Positives = 94/144 (65%), Gaps = 1/144 (0%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 LTE+Q E +EAF LFD D SG+I EL MR+LG P + E+ +++E+D + I Sbjct: 5 LTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGLSPSEAEVADLMNEIDVDGNHAI 64 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD E+ E Sbjct: 65 EFSEFLALMSRQLKCNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEVDE 124 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 M+ E DG GE+N ++F ++ K Sbjct: 125 MLREV-SDGSGEINIKQFAALLSK 147 Score = 28.0 bits (61), Expect = 2.4, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 21/42 (50%), Gaps = 3/42 (7%) Query: 133 LGESLTDE---ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + ++LT+E E +E D+D G ++ E +M+ L Sbjct: 1 MSQNLTEEQIAEFKEAFALFDKDNSGSISASELATVMRSLGL 42 >2LMV-A nrPDB Length = 148 Score = 150 bits (378), Expect = 4e-37, Method: Composition-based stats. Identities = 64/146 (43%), Positives = 96/146 (65%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 ELTE+Q E ++AF FD +G+G I +EL MR LG P + E++ +I+E + G Sbjct: 2 SELTEEQIAEFKDAFVQFDKEGTGKIATRELGTLMRTLGQNPTEAELQDLIAEAENNNNG 61 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEEL 142 +++F +F +M ++M E DT+EE+ +AF++FD D G IS L+ V LGE +TDEE+ Sbjct: 62 QLNFTEFCGIMAKQMRETDTEEEMREAFKIFDRDGDGFISPAELRFVMINLGEKVTDEEI 121 Query: 143 QEMIDEADRDGDGEVNEEEFLKIMKK 168 EMI EAD DGDG +N EEF+ ++ + Sbjct: 122 DEMIREADFDGDGMINYEEFVWMISQ 147 >1LKJ-A nrPDB Length = 146 Score = 148 bits (374), Expect = 1e-36, Method: Composition-based stats. Identities = 58/146 (39%), Positives = 95/146 (65%), Gaps = 1/146 (0%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + Sbjct: 2 SNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNH 61 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEEL 142 +I F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD E+ Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEV 121 Query: 143 QEMIDEADRDGDGEVNEEEFLKIMKK 168 +M+ E DG GE+N ++F ++ K Sbjct: 122 DDMLREV-SDGSGEINIQQFAALLSK 146 Score = 26.1 bits (56), Expect = 7.8, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 136 SLTDE---ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 +LT+E E +E D+D +G ++ E +M+ L Sbjct: 3 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGL 41 >2OBH-A nrPDB Length = 143 Score = 145 bits (365), Expect = 1e-35, Method: Composition-based stats. Identities = 124/143 (86%), Positives = 139/143 (97%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 TE+QKQE+REAFDLFD+DG+GTIDVKELKVAMRALGFEP+KEE+KKMISE+DKE TGK++ Sbjct: 1 TEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEIDKEGTGKMN 60 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F DFL VMTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEM Sbjct: 61 FGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEM 120 Query: 146 IDEADRDGDGEVNEEEFLKIMKK 168 IDEADRDGDGEV+E+EFL+IMKK Sbjct: 121 IDEADRDGDGEVSEQEFLRIMKK 143 >3HZT-A nrPDB Length = 467 Score = 142 bits (358), Expect = 9e-35, Method: Composition-based stats. Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 15/177 (8%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF-- 62 F+ S + + +G K T ++ +E+ + F D++G G +D KEL R L Sbjct: 289 FQSSQKLAQAAMLFMGSKLT-TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWK 347 Query: 63 ---------EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLF 113 + E+ ++ VD + G I +++F+ V ++E +L AF+ F Sbjct: 348 GDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMD-KQLLLSRERLLAAFQQF 406 Query: 114 DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 D D +GKI+ + L R+ + DE +++ E D++ DGEV+ EEF+++M+K Sbjct: 407 DSDGSGKITNEELGRLFGVT--EVDDETWHQVLQECDKNNDGEVDFEEFVEMMQKIC 461 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 35/75 (46%), Gaps = 2/75 (2%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++ + AF FDSDGSG I +EL E E +++ E DK G++ F + Sbjct: 395 SRERLLAAFQQFDSDGSGKITNEELGRLFGVT--EVDDETWHQVLQECDKNNDGEVDFEE 452 Query: 89 FLAVMTQKMAEKDTK 103 F+ +M + K Sbjct: 453 FVEMMQKICDVKVKH 467 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 11/91 (12%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL----KRVANELGESLTD-------E 140 M K+ + +E+ + FR D++ G++ K L +++ G++++D Sbjct: 302 FMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEA 361 Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 E+ ++ D D +G + EF+ + L Sbjct: 362 EVDHILQSVDFDRNGYIEYSEFVTVCMDKQL 392 >2TN4-A nrPDB Length = 159 Score = 139 bits (350), Expect = 6e-34, Method: Composition-based stats. Identities = 59/153 (38%), Positives = 95/153 (62%), Gaps = 3/153 (1%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 + L+E+ E + AFD+FD+DG G I VKEL MR LG P KEE+ +I EVD++ Sbjct: 7 ARSYLSEEMIAEFKAAFDMFDADGGGDISVKELGTVMRMLGQTPTKEELDAIIEEVDEDG 66 Query: 81 TGKISFNDFLAVMTQKMAEK---DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 +G I F +FL +M ++M E ++EE+ + FR+FD + G I + L + GE + Sbjct: 67 SGTIDFEEFLVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEHV 126 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 TDEE++ ++ + D++ DG ++ +EFLK+M+ Sbjct: 127 TDEEIESLMKDGDKNNDGRIDFDEFLKMMEGVQ 159 Score = 46.5 bits (109), Expect = 5e-06, Method: Composition-based stats. Identities = 30/110 (27%), Positives = 51/110 (46%), Gaps = 5/110 (4%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN- 125 E K D + G IS + VM + + + TKEE+ D+D +G I F+ Sbjct: 17 AEFKAAFDMFDADGGGDISVKELGTVM-RMLGQTPTKEELDAIIEEVDEDGSGTIDFEEF 75 Query: 126 ---LKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 + R E + ++EEL E+ DR+ DG ++ EE +I + + + Sbjct: 76 LVMMVRQMKEDAKGKSEEELAELFRIFDRNADGYIDAEELAEIFRASGEH 125 >1TOP-A nrPDB Length = 162 Score = 139 bits (350), Expect = 6e-34, Method: Composition-based stats. Identities = 56/149 (37%), Positives = 94/149 (63%), Gaps = 3/149 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+ E + AFD+FD+DG G I KEL MR LG P KEE+ +I EVD++ +G I Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 73 Query: 85 SFNDFLAVMTQKMAEK---DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 F +FL +M ++M E ++EE+ FR+FD + G I + L + GE +T+E+ Sbjct: 74 DFEEFLVMMVRQMKEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVTEED 133 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +++++ ++D++ DG ++ +EFLK+M+ Sbjct: 134 IEDLMKDSDKNNDGRIDFDEFLKMMEGVQ 162 Score = 72.7 bits (177), Expect = 7e-14, Method: Composition-based stats. Identities = 29/75 (38%), Positives = 41/75 (54%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + ++ E AF +FD D G IS K L V LG++ T EEL +I+E D DG Sbjct: 10 ARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDG 69 Query: 154 DGEVNEEEFLKIMKK 168 G ++ EEFL +M + Sbjct: 70 SGTIDFEEFLVMMVR 84 >2LAP-A nrPDB Length = 167 Score = 136 bits (343), Expect = 4e-33, Method: Composition-based stats. Identities = 47/165 (28%), Positives = 88/165 (53%), Gaps = 5/165 (3%) Query: 9 NVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE 68 N + L ++ +E+REAF FD D G I+ ++L MR +G+ P + E Sbjct: 3 NCVKYPLRNLSRKDRSLRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEME 62 Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQ----KMAEKDTKEEILKAFRLFDDDETGKISFK 124 + ++ +++ G + F+DF+ +M + A+ +E+ AFR FD + G+IS Sbjct: 63 LIELSQQINMNLGGHVDFDDFVELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTS 122 Query: 125 NLKRVANE-LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 L+ + LG + +++E+I + D +GDG V+ EEF+++M + Sbjct: 123 ELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFVRMMSR 167 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 24/110 (21%), Positives = 41/110 (37%), Gaps = 41/110 (37%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTD------------------------ 139 EE+ +AFR FD D+ G I+ ++L +G T+ Sbjct: 25 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFV 84 Query: 140 -----------------EELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 +EL++ E D +GDGE++ E + M+K + Sbjct: 85 ELMGPKLLAETADMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGH 134 >3FWC-A nrPDB Length = 161 Score = 135 bits (341), Expect = 7e-33, Method: Composition-based stats. Identities = 82/148 (55%), Positives = 106/148 (71%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 EL E+QKQE+ EAF LFD + G +D ELKVAM+ALGFE K E+ +I E D E Sbjct: 14 NSELLEEQKQEIYEAFSLFDMNNDGFLDYHELKVAMKALGFELPKREILDLIDEYDSEGR 73 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 + ++DF VM +K+ ++D +EI +AF+LFDDD TGKIS KNL+RVA ELGE+LTDEE Sbjct: 74 HLMKYDDFYIVMGEKILKRDPLDEIKRAFQLFDDDHTGKISIKNLRRVAKELGETLTDEE 133 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKT 169 L+ MI+E D DGDGE+NE EF+ I + Sbjct: 134 LRAMIEEFDLDGDGEINENEFIAICTDS 161 >1W7I-B nrPDB Length = 151 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 49/146 (33%), Positives = 78/146 (53%), Gaps = 5/146 (3%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKE--A 80 E +DQ +E +EAF+LFD G G I + MRALG P E+ K++ + Sbjct: 2 IEFNKDQLEEFKEAFELFDRVGDGKILYSQCGDVMRALGQNPTNAEVLKVLGNPKSDELK 61 Query: 81 TGKISFNDFLAVM--TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLT 138 + ++ F FL ++ K + T E+ L+ FR+FD + GK+ L+ V LGE +T Sbjct: 62 SRRVDFETFLPMLQAVAKNRGQGTYEDYLEGFRVFDKEGNGKVMGAELRHVLTTLGEKMT 121 Query: 139 DEELQEMIDEADRDGDGEVNEEEFLK 164 +EE++ ++ D +G +N E FLK Sbjct: 122 EEEVETVLA-GHEDSNGCINYEAFLK 146 >3LIJ-A nrPDB Length = 494 Score = 130 bits (327), Expect = 3e-31, Method: Composition-based stats. Identities = 43/174 (24%), Positives = 81/174 (46%), Gaps = 12/174 (6%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL---- 60 F+ S + + + K ++++ +E+ + F D +G G +D +EL L Sbjct: 321 FQNSQKLAQAALLYMASKLT-SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEE 379 Query: 61 ----GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDD 116 + E+ ++ D + G I +++F+ V + + K+++ AF+ FD D Sbjct: 380 VAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLS-KDKLESAFQKFDQD 438 Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 GKIS L V + L + +EMI D + DG+V+ EEF K+++K Sbjct: 439 GNGKISVDELASVFGL--DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLC 490 >2LC5-A nrPDB Length = 151 Score = 129 bits (325), Expect = 6e-31, Method: Composition-based stats. Identities = 54/145 (37%), Positives = 90/145 (62%), Gaps = 1/145 (0%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 K LT +++QE +EAF LFD D + +EL MRALG P K+++ +++ + DK+ + Sbjct: 5 KKVLTAEEQQEYKEAFQLFDKDNDNKLTAEELGTVMRALGANPTKQKISEIVKDYDKDNS 64 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 GK FL +M + E D+ E+I KAF +FD ++ G IS LK V LGE LT++E Sbjct: 65 GKFDQETFLTIMLEYGQEVDSTEDIKKAFEIFDKEKNGYISASELKHVLTTLGEKLTEQE 124 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIM 166 + +++ E + +G +N ++F+K++ Sbjct: 125 VDDLLKEIGVE-EGLINVDDFVKLI 148 >3KHE-A nrPDB Length = 191 Score = 128 bits (323), Expect = 9e-31, Method: Composition-based stats. Identities = 48/177 (27%), Positives = 88/177 (49%), Gaps = 15/177 (8%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF-- 62 F+ S + + +G K T ++ +E+ + F D++G G +D KEL R L Sbjct: 15 FQSSQKLAQAAMLFMGSKLT-TLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWK 73 Query: 63 ---------EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLF 113 + E+ ++ VD + G I +++F+ V ++E +L AF+ F Sbjct: 74 GDTVSDLDSSQIEAEVDHILQSVDFDRNGYIEYSEFVTVCMD-KQLLLSRERLLAAFQQF 132 Query: 114 DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 D D +GKI+ + L R+ + DE +++ E D++ DGEV+ EEF+++M+K Sbjct: 133 DSDGSGKITNEELGRLFGVT--EVDDETWHQVLQECDKNNDGEVDFEEFVEMMQKIC 187 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 22/72 (30%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++ + AF FDSDGSG I +EL E E +++ E DK G++ F + Sbjct: 121 SRERLLAAFQQFDSDGSGKITNEELGRLFGVT--EVDDETWHQVLQECDKNNDGEVDFEE 178 Query: 89 FLAVMTQKMAEK 100 F+ +M + K Sbjct: 179 FVEMMQKICDVK 190 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 11/91 (12%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL----KRVANELGESLTD-------E 140 M K+ + +E+ + FR D++ G++ K L +++ G++++D Sbjct: 28 FMGSKLTTLEETKELTQIFRQLDNNGDGQLDRKELIEGYRKLMQWKGDTVSDLDSSQIEA 87 Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 E+ ++ D D +G + EF+ + L Sbjct: 88 EVDHILQSVDFDRNGYIEYSEFVTVCMDKQL 118 >3JAX-C nrPDB Length = 151 Score = 128 bits (323), Expect = 9e-31, Method: Composition-based stats. Identities = 43/147 (29%), Positives = 78/147 (53%), Gaps = 5/147 (3%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMIS--EVDKEAT 81 + +E+Q E +EAF LFD G G I + MRALG P E+ K++ + D+ Sbjct: 3 DFSEEQTAEFKEAFQLFDRTGDGKILYSQCGDVMRALGQNPTNAEVMKVLGNPKSDEMNL 62 Query: 82 GKISFNDFLAVMTQ--KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 + F FL +M K ++ E+ ++ R+FD + G + ++ V LGE +T+ Sbjct: 63 KTLKFEQFLPMMQTIAKNKDQGCFEDYVEGLRVFDKEGNGTVMGAEIRHVLVTLGEKMTE 122 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIM 166 EE+++++ D +G +N EE ++++ Sbjct: 123 EEVEQLVA-GHEDSNGCINYEELVRMV 148 >2LHH-A nrPDB Length = 128 Score = 128 bits (321), Expect = 1e-30, Method: Composition-based stats. Identities = 50/121 (41%), Positives = 80/121 (66%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + Sbjct: 2 SNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNH 61 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEEL 142 +I F++FLA+M++++ D+++E+L+AF++FD + G IS LK V +GE LTD EL Sbjct: 62 QIEFSEFLALMSRQLKSNDSEQELLEAFKVFDKNGDGLISAAELKHVLTSIGEKLTDAEL 121 Query: 143 Q 143 + Sbjct: 122 E 122 Score = 68.1 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 24/64 (37%), Positives = 37/64 (57%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G IS L V LG S ++ E+ ++++E D DG+ ++ EFL Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLA 70 Query: 165 IMKK 168 +M + Sbjct: 71 LMSR 74 Score = 26.1 bits (56), Expect = 8.8, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 136 SLTDE---ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 +LT+E E +E D+D +G ++ E +M+ L Sbjct: 3 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGL 41 >5JN2-A nrPDB Length = 525 Score = 127 bits (319), Expect = 3e-30, Method: Composition-based stats. Identities = 42/180 (23%), Positives = 84/180 (46%), Gaps = 15/180 (8%) Query: 2 ASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG 61 F+ + + + +G K ++D+ +E+ F D +G G +D EL + L Sbjct: 348 IRQFQGTQKLAQAALLYMGSKLT-SQDETKELTAIFHKMDKNGDGQLDRAELIEGYKELM 406 Query: 62 FEPRKE-----------EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 ++ E+ +++ VD + G I +++F+ V + +E + +AF Sbjct: 407 RMKGQDASMLDASAVEHEVDQVLDAVDFDKNGYIEYSEFVTVAMDRKTLLS-RERLERAF 465 Query: 111 RLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 R+FD D +GKIS L + + E + ++ E D++ DGEV+ +EF +++ K Sbjct: 466 RMFDSDNSGKISSTELATIFGV--SDVDSETWKSVLSEVDKNNDGEVDFDEFQQMLLKLC 523 >1DTL-A nrPDB Length = 161 Score = 126 bits (318), Expect = 4e-30, Method: Composition-based stats. Identities = 55/156 (35%), Positives = 94/156 (60%), Gaps = 4/156 (2%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEV 76 +LTE+QK E + AFD+F G+I KEL MR LG P EE+++MI EV Sbjct: 5 YKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV 64 Query: 77 DKEATGKISFNDFLAVMTQKMAEKDT---KEEILKAFRLFDDDETGKISFKNLKRVANEL 133 D++ +G + F++FL +M + M + +EE+ FR+FD + G I + LK + Sbjct: 65 DEDGSGTVDFDEFLVMMVRSMKDDSKGKSEEELSDLFRMFDKNADGYIDLEELKIMLQAT 124 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 GE++T+++++E++ + D++ DG ++ +EFL+ MK Sbjct: 125 GETITEDDIEELMKDGDKNNDGRIDYDEFLEFMKGV 160 Score = 68.8 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 33/72 (45%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Query: 100 KDTKEEILKAFRLFD-DDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 ++ K E AF +F E G IS K L +V LG++ T EELQEMIDE D DG G V+ Sbjct: 14 EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 73 Query: 159 EEEFLKIMKKTN 170 +EFL +M ++ Sbjct: 74 FDEFLVMMVRSM 85 >3J04-B nrPDB Length = 143 Score = 126 bits (316), Expect = 5e-30, Method: Composition-based stats. Identities = 49/144 (34%), Positives = 79/144 (54%), Gaps = 4/144 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 + Q QE +EAF++ D + G ID ++L + ++G P E ++ M+SE A G I Sbjct: 1 FDQSQIQEFKEAFNMIDQNRDGFIDKEDLHDMLASMGKNPTDEYLEGMMSE----APGPI 56 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +F FL + +K+ D ++ I AF FD++ +G I +L+ + +G+ TDEE+ E Sbjct: 57 NFTMFLTMFGEKLNGTDPEDVIRNAFACFDEEASGFIHEDHLRELLTTMGDRFTDEEVDE 116 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 M EA D G N EF +I+K Sbjct: 117 MYREAPIDKKGNFNYVEFTRILKH 140 >2AAO-A nrPDB Length = 166 Score = 126 bits (316), Expect = 5e-30, Method: Composition-based stats. Identities = 40/147 (27%), Positives = 86/147 (58%), Gaps = 3/147 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E++ ++E F++ D+D SG I +ELK ++ +G ++ E+ ++ D + +G I Sbjct: 21 LSEEEIAGLKEMFNMIDADKSGQITFEELKAGLKRVGANLKESEILDLMQAADVDNSGTI 80 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 + +F+A T + + + ++ + AF FD D +G I+ L++ E G + D ++E Sbjct: 81 DYKEFIAA-TLHLNKIEREDHLFAAFTYFDKDGSGYITPDELQQACEEFG--VEDVRIEE 137 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKTNL 171 ++ + D+D DG ++ EF+ +M+K ++ Sbjct: 138 LMRDVDQDNDGRIDYNEFVAMMQKGSI 164 >1S6I-A nrPDB Length = 188 Score = 125 bits (313), Expect = 1e-29, Method: Composition-based stats. Identities = 44/144 (30%), Positives = 83/144 (57%), Gaps = 3/144 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E++ ++E F + D+D SGTI ELK ++ +G E + E+K ++ D + +G I Sbjct: 4 LSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTI 63 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 + +F+A + + + +E ++ AF FD D +G I+ +++ + G L D + + Sbjct: 64 DYGEFIAATV-HLNKLEREENLVSAFSYFDKDGSGYITLDEIQQACKDFG--LDDIHIDD 120 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 MI E D+D DG+++ EF +M+K Sbjct: 121 MIKEIDQDNDGQIDYGEFAAMMRK 144 Score = 28.8 bits (63), Expect = 1.1, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 3/39 (7%) Query: 135 ESLTDEEL---QEMIDEADRDGDGEVNEEEFLKIMKKTN 170 E L++EE+ +E+ D D G + +E +K+ Sbjct: 2 ERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVG 40 >3Q5I-A nrPDB Length = 504 Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats. Identities = 45/176 (25%), Positives = 91/176 (51%), Gaps = 12/176 (6%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG--- 61 F S + + +G K T ++++E+ + F D +G G +D KEL L Sbjct: 330 FEGSQKLAQAAILFIGSKLT-TLEERKELTDIFKKLDKNGDGQLDKKELIEGYNVLRNFK 388 Query: 62 -----FEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDD 116 + +EE+ ++ EVD + G I +++F++V K ++E + +AF LFD D Sbjct: 389 NELGELKNVEEEVDNILKEVDFDKNGYIEYSEFISVCMDKQI-LFSEERLRRAFNLFDTD 447 Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 ++GKI+ + L + S++++ +++ EAD++ D ++ +EF+ +M K + Sbjct: 448 KSGKITKEELANLFGLT--SISEKTWNDVLGEADQNKDNMIDFDEFVSMMHKICDH 501 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++ +R AF+LFD+D SG I +EL ++ ++ E D+ I F++ Sbjct: 433 SEERLRRAFNLFDTDKSGKITKEELANLFGLTSI--SEKTWNDVLGEADQNKDNMIDFDE 490 Query: 89 FLAVMTQKMAEKDT 102 F+++M + K Sbjct: 491 FVSMMHKICDHKTF 504 >4RGJ-A nrPDB Length = 520 Score = 124 bits (312), Expect = 2e-29, Method: Composition-based stats. Identities = 44/182 (24%), Positives = 88/182 (48%), Gaps = 15/182 (8%) Query: 2 ASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG 61 F+ + + + +G K T D+ +E+ + F D +G G +D EL + + L Sbjct: 343 IRQFQSTQKLAQAALLYMGSKLT-TIDETKELTKIFKKMDKNGDGQLDRNELIIGYKELL 401 Query: 62 FEPRKE-----------EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 ++ E+ ++++ +D + G I +++FL V + + E + KAF Sbjct: 402 KLKGEDTSDLDNAAIEYEVDQILNSIDLDQNGYIEYSEFLTV-SIDRKLLLSTERLEKAF 460 Query: 111 RLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +LFD D +GKIS L ++ ++ E + ++ E D++ DGE++ +EF ++ K Sbjct: 461 KLFDKDGSGKISANELAQLFGL--SDVSSECWKTVLKEVDQNNDGEIDFKEFRDMLVKLC 518 Query: 171 LY 172 Y Sbjct: 519 NY 520 >4MVF-A nrPDB Length = 506 Score = 123 bits (309), Expect = 4e-29, Method: Composition-based stats. Identities = 48/168 (28%), Positives = 85/168 (50%), Gaps = 5/168 (2%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 F+K N + L + + +R F D D SGT+ +E+ ++ +G++ Sbjct: 335 NFKKENELKKIALTIIA--KHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQ 392 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 ++ +++ ++D A+G+I + DFLA K KE L F+ FD D GKIS Sbjct: 393 KIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLK-KEVCLIPFKFFDIDGNGKISV 451 Query: 124 KNLKRVAN--ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 + LKR+ ++ L D+ + ++ E D +GDGE++ EF+ +M K Sbjct: 452 EELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSKL 499 >6FSA-D nrPDB Length = 199 Score = 122 bits (307), Expect = 6e-29, Method: Composition-based stats. Identities = 43/149 (28%), Positives = 78/149 (52%), Gaps = 7/149 (4%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSG--TIDVKELKVAMRALGFEPRKEEMKKMISEVDKE 79 K E T +Q +E +EAF LFD I + +RALG P + E+ +++ + +E Sbjct: 47 KIEFTPEQIEEFKEAFTLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGKPKQE 106 Query: 80 --ATGKISFNDFLAVMTQ--KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 + + F+ FL ++ K + T E+ ++ R+FD + G + L+ V LGE Sbjct: 107 ELNSKMMDFDTFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGE 166 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLK 164 LT++E+++++ D +G +N E F+K Sbjct: 167 KLTEDEVEKLMA-GQEDSNGCINYEAFVK 194 >3DTP-E nrPDB Length = 196 Score = 122 bits (307), Expect = 7e-29, Method: Composition-based stats. Identities = 47/155 (30%), Positives = 81/155 (52%), Gaps = 5/155 (3%) Query: 14 SYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMI 73 + + T+ Q QE +EAF L D D G I +++ +LG ++E+ M+ Sbjct: 40 AQRSGSNVFAMFTQHQVQEFKEAFQLIDQDKDGFISKNDIRATFDSLGRLCTEQELDSMV 99 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 +E A G I+F FL + ++A D ++ I+ AF LFD + GK + LKR Sbjct: 100 AE----APGPINFTMFLTIFGDRIAGTDEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTW 154 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 GE + +E+ + + EA DG+G ++ ++F +I+ K Sbjct: 155 GEKFSQDEVDQALSEAPIDGNGLIDIKKFAQILTK 189 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 38/74 (51%), Gaps = 1/74 (1%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D++ + AF+LFD +G G + LK ++ G + ++E+ + +SE + G I Sbjct: 123 DEEDVIVNAFNLFD-EGDGKCKEETLKRSLTTWGEKFSQDEVDQALSEAPIDGNGLIDIK 181 Query: 88 DFLAVMTQKMAEKD 101 F ++T+ E+ Sbjct: 182 KFAQILTKGAKEEG 195 >3L19-A nrPDB Length = 214 Score = 121 bits (305), Expect = 1e-28, Method: Composition-based stats. Identities = 43/174 (24%), Positives = 81/174 (46%), Gaps = 12/174 (6%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL---- 60 F+ S + + + K ++++ +E+ + F D +G G +D +EL L Sbjct: 38 FQNSQKLAQAALLYMASKLT-SQEETKELTDIFRHIDKNGDGQLDRQELIDGYSKLSGEE 96 Query: 61 ----GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDD 116 + E+ ++ D + G I +++F+ V + + K+++ AF+ FD D Sbjct: 97 VAVFDLPQIESEVDAILGAADFDRNGYIDYSEFVTVAMDRKSLLS-KDKLESAFQKFDQD 155 Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 GKIS L V + L + +EMI D + DG+V+ EEF K+++K Sbjct: 156 GNGKISVDELASVFGL--DHLESKTWKEMISGIDSNNDGDVDFEEFCKMIQKLC 207 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 2/74 (2%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 K ++ AF FD DG+G I V EL + K+MIS +D G + F + Sbjct: 141 SKDKLESAFQKFDQDGNGKISVDELASVFGL--DHLESKTWKEMISGIDSNNDGDVDFEE 198 Query: 89 FLAVMTQKMAEKDT 102 F ++ + + + Sbjct: 199 FCKMIQKLCSNNEP 212 >2M29-A nrPDB Length = 171 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 47/138 (34%), Positives = 76/138 (55%), Gaps = 5/138 (3%) Query: 35 EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 AF+ FD+D G I +EL MR LG+ P + E+ ++ V G + F +F+ +++ Sbjct: 32 AAFEEFDTDQDGYIGYRELGDCMRTLGYMPTEMELLEVSQHVKMRMGGFVDFEEFVELIS 91 Query: 95 QKMAEKDTK----EEILKAFRLFDDDETGKISFKNLKRVA-NELGESLTDEELQEMIDEA 149 K+ E+ E+ AFR FD D G+I+ L++ A LGE L EL EM+ E Sbjct: 92 PKLREETAHMLGVRELRIAFREFDKDRDGRITVAELRQAAPALLGEPLEGTELDEMLREM 151 Query: 150 DRDGDGEVNEEEFLKIMK 167 D +GDG ++ +EF+ ++ Sbjct: 152 DLNGDGTIDFDEFVMMLS 169 >5H53-C nrPDB Length = 153 Score = 121 bits (304), Expect = 2e-28, Method: Composition-based stats. Identities = 44/153 (28%), Positives = 78/153 (50%), Gaps = 5/153 (3%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD--KE 79 K E +++Q+ E +EAF L+D G I + ++ +RALG P E+KK++ + Sbjct: 2 KIEFSKEQQDEFKEAFLLYDRTGDSKITLSQVGDVLRALGTNPTNAEVKKVLGNPSNEEM 61 Query: 80 ATGKISFNDFLAVMTQKMAEKDT--KEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 KI F FL ++ KD E+ ++ R+FD + G + L+ V LGE + Sbjct: 62 NAKKIEFEQFLPMLQAISNNKDQGTYEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKM 121 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +EE++ ++ D +G +N E F+K + + Sbjct: 122 KEEEVEALMA-GQEDSNGCINYEAFVKHIMSID 153 >5TBY-C nrPDB Length = 195 Score = 121 bits (303), Expect = 2e-28, Method: Composition-based stats. Identities = 44/158 (27%), Positives = 79/158 (50%), Gaps = 7/158 (4%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDGSG--TIDVKELKVAMRALGFEPRKEEMKKMISE 75 K E T +Q +E +EAF LFD I + +RALG P + E+ +++ + Sbjct: 39 ASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRVLGK 98 Query: 76 VDKE--ATGKISFNDFLAVMTQ--KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN 131 +E T + F FL ++ K + T E+ ++ R+FD + G + L+ V Sbjct: 99 PRQEELNTKMMDFETFLPMLQHISKNKDTGTYEDFVEGLRVFDKEGNGTVMGAELRHVLA 158 Query: 132 ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 LGE LT++E+++++ D +G +N E F+K + + Sbjct: 159 TLGERLTEDEVEKLMA-GQEDSNGCINYEAFVKHIMSS 195 Score = 35.3 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 39/87 (44%), Gaps = 4/87 (4%) Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDD--DETGKISFKNLKRVANELGESLTDEELQEM 145 +F A + + EE +AF LFD KI++ V LG++ T E+ + Sbjct: 36 EFDASKIKIEFTPEQIEEFKEAFMLFDRTPKCEMKITYGQCGDVLRALGQNPTQAEVLRV 95 Query: 146 IDEADRD--GDGEVNEEEFLKIMKKTN 170 + + ++ ++ E FL +++ + Sbjct: 96 LGKPRQEELNTKMMDFETFLPMLQHIS 122 >4WPX-A nrPDB Length = 177 Score = 120 bits (301), Expect = 3e-28, Method: Composition-based stats. Identities = 49/158 (31%), Positives = 91/158 (57%), Gaps = 12/158 (7%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-PRKEEMKKMISEVDKE 79 +L+++QK + EAF+LFDS+ G + +E + +RALGF+ P+++ ++ + Sbjct: 16 DYNKLSDEQKTRISEAFELFDSNKDGLLSYEEFRFVLRALGFDLPKQQTYDMLVRHGQRP 75 Query: 80 ATGKIS------FNDFLAVMTQK-----MAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 A + F Q + ++D ++E+ +AFRLFD D G I+ +L++ Sbjct: 76 ANWPHDQECPPVYRQFNLATAQALAGTLIRQRDPRDELRRAFRLFDVDGKGMITEDDLRK 135 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 V ++G ++ D ++Q MI+E D +G G V+E+EFL++M Sbjct: 136 VCQQVGNNIPDADIQAMIEEFDSNGKGGVDEDEFLRLM 173 Score = 66.1 bits (160), Expect = 7e-12, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 35/68 (51%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 D + E+R AF LFD DG G I +L+ + +G +++ MI E D G + Sbjct: 107 RDPRDELRRAFRLFDVDGKGMITEDDLRKVCQQVGNNIPDADIQAMIEEFDSNGKGGVDE 166 Query: 87 NDFLAVMT 94 ++FL +M Sbjct: 167 DEFLRLMM 174 >4YZB-A nrPDB Length = 491 Score = 118 bits (297), Expect = 9e-28, Method: Composition-based stats. Identities = 43/180 (23%), Positives = 83/180 (46%), Gaps = 15/180 (8%) Query: 2 ASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAM---- 57 F+ + + + +G K T ++ E+ + F D +G G +D +EL Sbjct: 311 IRQFQGTQKLAAAALLYMGSKLT-TNEETVELNKIFQRMDKNGDGQLDKQELMEGYVELM 369 Query: 58 -------RALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 AL + E+++++ VD + G I +++F+ V + ++ + +AF Sbjct: 370 KLKGEDVSALDQSAIEFEVEQVLDAVDFDKNGFIEYSEFVTVAMDRKTLLS-RQRLERAF 428 Query: 111 RLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +FD D +GKIS L + + E + ++ E DR+ DGEV+ EEF +++ K Sbjct: 429 GMFDADGSGKISSSELATIFGV--SEVDSETWRRVLAEVDRNNDGEVDFEEFRQMLLKLC 486 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 2/72 (2%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 +Q + AF +FD+DGSG I EL E E +++++EVD+ G++ F + Sbjct: 420 SRQRLERAFGMFDADGSGKISSSELATIFGV--SEVDSETWRRVLAEVDRNNDGEVDFEE 477 Query: 89 FLAVMTQKMAEK 100 F ++ + + Sbjct: 478 FRQMLLKLCGDT 489 >2BL0-B nrPDB Length = 145 Score = 118 bits (295), Expect = 1e-27, Method: Composition-based stats. Identities = 41/143 (28%), Positives = 72/143 (50%), Gaps = 7/143 (4%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 + DQ QE F +FD D G + ++EL A+R+LG P E+ + +++ + Sbjct: 3 SADQIQE---CFQIFDKDNDGKVSIEELGSALRSLGKNPTNAELNTIKGQLNA---KEFD 56 Query: 86 FNDFLAVMTQK-MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 F V + + +E+L AFR D + G I L+++ LG++LT E++E Sbjct: 57 LATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEE 116 Query: 145 MIDEADRDGDGEVNEEEFLKIMK 167 ++ E GDG +N E F+ ++ Sbjct: 117 LMKEVSVSGDGAINYESFVDMLV 139 Score = 63.4 bits (153), Expect = 5e-11, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 41/82 (50%) Query: 13 TSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKM 72 ++K + +Q +E+ +AF D +G+GTI EL+ + LG E++++ Sbjct: 58 ATFKTVYRKPIKTPTEQSKEMLDAFRALDKEGNGTIQEAELRQLLLNLGDALTSSEVEEL 117 Query: 73 ISEVDKEATGKISFNDFLAVMT 94 + EV G I++ F+ ++ Sbjct: 118 MKEVSVSGDGAINYESFVDMLV 139 >5ZOR-A nrPDB Length = 149 Score = 117 bits (294), Expect = 2e-27, Method: Composition-based stats. Identities = 73/146 (50%), Positives = 105/146 (71%), Gaps = 4/146 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF-EPRKEEMKKMISEVDKEATGK 83 LT++Q REAF+LFD+DGSG ID +E+ +AM+ LGF + ++E+++ + ++ A G Sbjct: 4 LTDEQI---REAFNLFDADGSGAIDAEEMALAMKGLGFGDLPRDEVERTVRSMNTNANGL 60 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I + +F ++ +MA+KD+ EE+LKAF+LFD D+ GKISF NLK VA LGE+ D+ LQ Sbjct: 61 IEYGEFERMVKSRMAQKDSPEEVLKAFQLFDLDKKGKISFANLKEVAKLLGENPGDDVLQ 120 Query: 144 EMIDEADRDGDGEVNEEEFLKIMKKT 169 EMI EAD DGDGEV+ EEF +M + Sbjct: 121 EMIAEADEDGDGEVSFEEFKSVMMQM 146 Score = 29.9 bits (66), Expect = 0.56, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 19/34 (55%) Query: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 LTDE+++E + D DG G ++ EE MK Sbjct: 4 LTDEQIREAFNLFDADGSGAIDAEEMALAMKGLG 37 >3PM8-A nrPDB Length = 197 Score = 117 bits (293), Expect = 2e-27, Method: Composition-based stats. Identities = 48/167 (28%), Positives = 85/167 (50%), Gaps = 5/167 (2%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 F+K N + L + + +R F D D SGT+ +E+ ++ +G++ Sbjct: 32 NFKKENELKKIALTIIA--KHLCDVEINNLRNIFIALDVDNSGTLSSQEILDGLKKIGYQ 89 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 ++ +++ ++D A+G+I + DFLA K KE L F+ FD D GKIS Sbjct: 90 KIPPDIHQVLRDIDSNASGQIHYTDFLAATIDKQTYLK-KEVCLIPFKFFDIDGNGKISV 148 Query: 124 KNLKRVAN--ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + LKR+ ++ L D+ + ++ E D +GDGE++ EF+ +M K Sbjct: 149 EELKRIFGRDDIENPLIDKAIDSLLQEVDLNGDGEIDFHEFMLMMSK 195 >2OS8-B nrPDB Length = 157 Score = 116 bits (290), Expect = 5e-27, Method: Composition-based stats. Identities = 46/155 (29%), Positives = 88/155 (56%), Gaps = 5/155 (3%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE 75 K G +L + Q QE++EAF + D + G ID+ +LK +LG P +E+ M+ Sbjct: 4 KAASGVLTKLPQKQIQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML-- 61 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 KEA G ++F FL++ + K++ D++E I AF +FD+ +T K++ + +K + +G+ Sbjct: 62 --KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENMGD 119 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 + +E++ EA +G G+ + F+ ++K + Sbjct: 120 NFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIKGSG 153 >3NCG-A nrPDB Length = 486 Score = 116 bits (290), Expect = 6e-27, Method: Composition-based stats. Identities = 43/181 (23%), Positives = 91/181 (50%), Gaps = 16/181 (8%) Query: 2 ASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVA----M 57 F+ + + + K T D+ +++ E F D++ G +D EL M Sbjct: 303 IRQFQAEKKLAQAALLYMASKLT-TLDETKQLTEIFRKLDTNNDGMLDRDELVRGYHEFM 361 Query: 58 RALGFEPR----------KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEIL 107 R G + ++++ ++ +D + +G I +++F+A + +E + Sbjct: 362 RLKGVDSNSLIQNEGSTIEDQIDSLMPLLDMDGSGSIEYSEFIASAIDRTILLS-RERME 420 Query: 108 KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +AF++FD D +GKIS K L ++ ++ S+ EEL+ +I++ D + DGEV+ EF+++++ Sbjct: 421 RAFKMFDKDGSGKISTKELFKLFSQADSSIQMEELESIIEQVDNNKDGEVDFNEFVEMLQ 480 Query: 168 K 168 Sbjct: 481 N 481 >5TBY-E nrPDB Length = 166 Score = 115 bits (289), Expect = 9e-27, Method: Composition-based stats. Identities = 43/151 (28%), Positives = 72/151 (47%), Gaps = 5/151 (3%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVD 77 + Q QE +EAF + D + G ID +L+ ALG + EE+ +MI Sbjct: 15 SNVFSMFEQTQIQEFKEAFTIMDQNRDGFIDKNDLRDTFAALGRVNVKNEEIDEMI---- 70 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 KEA G I+F FL + +K+ D +E IL AF++FD + G + ++ + E Sbjct: 71 KEAPGPINFTVFLTMFGEKLKGADPEETILNAFKVFDPEGKGVLKADYVREMLTTQAERF 130 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + EE+ +M D G ++ + + I+ Sbjct: 131 SKEEVDQMFAAFPPDVTGNLDYKNLVHIITH 161 >2W4G-C nrPDB Length = 145 Score = 115 bits (287), Expect = 2e-26, Method: Composition-based stats. Identities = 45/141 (31%), Positives = 75/141 (53%), Gaps = 5/141 (3%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT--GKIS 85 D+ + +EAF LFD G I + ++ +RALG P E+ K++ KE KI+ Sbjct: 1 DEINDFKEAFLLFDRTGDAKITLSQVGDIVRALGQNPTNAEINKILGNPSKEEMNAKKIT 60 Query: 86 FNDFLAVMTQKMAEKDT--KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 F +FL ++ KD E+ ++ R+FD + G + L+ V LGE +T+EE++ Sbjct: 61 FEEFLPMLQAAANNKDQGTFEDFVEGLRVFDKEGNGTVMGAELRHVLATLGEKMTEEEVE 120 Query: 144 EMIDEADRDGDGEVNEEEFLK 164 E++ D +G +N E F+K Sbjct: 121 ELMK-GQEDSNGCINYEAFVK 140 >2JNF-A nrPDB Length = 158 Score = 114 bits (286), Expect = 2e-26, Method: Composition-based stats. Identities = 47/157 (29%), Positives = 89/157 (56%), Gaps = 5/157 (3%) Query: 19 VGPKPELTEDQKQEVREAFDLFDS-DGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD 77 +G +L+ +Q + + AF F++ +GSG + ++ + + LG + K ++++I E D Sbjct: 1 MGDVSKLSSNQVKLLETAFRDFETPEGSGRVSTDQIGIILEVLGIQQTKSTIRQLIDEFD 60 Query: 78 KEATGKISFNDFLAV----MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 G I F+ F + + +++ + ++E+ +AFRL+D + G IS ++ + EL Sbjct: 61 PFGNGDIDFDSFKIIGARFLGEEVNPEQMQQELREAFRLYDKEGNGYISTDVMREILAEL 120 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 E+L+ E+L MIDE D DG G V+ EEF+ +M + Sbjct: 121 DETLSSEDLDAMIDEIDADGSGTVDFEEFMGVMTGGD 157 >5E37-A nrPDB Length = 356 Score = 112 bits (281), Expect = 6e-26, Method: Composition-based stats. Identities = 38/174 (21%), Positives = 79/174 (45%), Gaps = 9/174 (5%) Query: 7 KSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE--- 63 +S G + ++ + +E+ F + D DG+G ID +EL+ + ++ Sbjct: 5 RSVRVVPRAATFEGLMDDASKAKMEELERRFKMADVDGNGHIDREELRNLLESMESGEVY 64 Query: 64 ------PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDE 117 ++E+++ + + D G ISF +F ++ + + T E AF+ D Sbjct: 65 MMSQHWLPEDELERCMEQYDVNKDGVISFEEFKQIIYDGLLLEGTLAEYESAFKAVDKSG 124 Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 G I L ++ LG ++ E+L +++ D+D G++ EFL + + + L Sbjct: 125 NGTIGATELSKLFASLGNPVSLEKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLL 178 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 31/80 (38%), Gaps = 5/80 (6%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 +++ + ++D D SG I+ E + R + + + E ++G + + Sbjct: 147 EKLVDLMQMYDKDDSGQIEFPEFLLMFRNSLLDLKDMTTYMTLDEAGAGSSGSL-----V 201 Query: 91 AVMTQKMAEKDTKEEILKAF 110 + M ++EE+ Sbjct: 202 DAVEGDMTLIFSEEELDALI 221 >2BL0-C nrPDB Length = 142 Score = 112 bits (281), Expect = 6e-26, Method: Composition-based stats. Identities = 42/140 (30%), Positives = 74/140 (52%), Gaps = 1/140 (0%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +DQ E +EAF+LFDS+ +G I + L+ ++ G +M +E D GKI F Sbjct: 2 DDQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQF 61 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 +FL++M ++M + +++ + +AFR FD + TG I L+ LG+ L E E + Sbjct: 62 PEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAALQDALLNLGDRLKPHEFAEFL 121 Query: 147 DEADRDGDGEVNEEEFLKIM 166 + + G++ + F+ M Sbjct: 122 GITETEK-GQIRYDNFINTM 140 Score = 62.7 bits (151), Expect = 9e-11, Method: Composition-based stats. Identities = 24/68 (35%), Positives = 37/68 (54%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D E +AF LFD + TG I+ + L+ V + G + EM +EAD G+G++ Sbjct: 3 DQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNEADATGNGKIQFP 62 Query: 161 EFLKIMKK 168 EFL +M + Sbjct: 63 EFLSMMGR 70 >1B7T-Y nrPDB Length = 156 Score = 112 bits (280), Expect = 8e-26, Method: Composition-based stats. Identities = 45/155 (29%), Positives = 86/155 (55%), Gaps = 5/155 (3%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE 75 K G +L + Q QE++EAF + D D G + +++K LG P +E+ M+ Sbjct: 3 KAASGVLTKLPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML-- 60 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 KEA G ++F FL++ + K++ D++E I AF +FD+ ET K++ + +K + +G+ Sbjct: 61 --KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGD 118 Query: 136 SLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 + +E++ EA +G G+ + +F ++K + Sbjct: 119 NFNKDEMRMTFKEAPVEG-GKFDYVKFTAMIKGSG 152 >1SR6-C nrPDB Length = 156 Score = 112 bits (280), Expect = 9e-26, Method: Composition-based stats. Identities = 49/147 (33%), Positives = 79/147 (53%), Gaps = 6/147 (4%) Query: 23 PELTEDQKQEVREAFDLFD-SDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 P+L++D+ ++++ F+LFD DG G +D +L R LG PR E++ + K Sbjct: 1 PKLSQDEIDDLKDVFELFDFWDGRDGAVDAFKLGDVCRCLGINPRNEDVFA-VGGTHKMG 59 Query: 81 TGKISFNDFLAVMTQKM-AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 + F +FL M E+ T + ++AF+ FD + G IS L+ V LGE L+D Sbjct: 60 EKSLPFEEFLPAYEGLMDCEQGTFADYMEAFKTFDREGQGFISGAELRHVLTALGERLSD 119 Query: 140 EELQEMIDEAD--RDGDGEVNEEEFLK 164 E++ E+I D D +G V E+F+K Sbjct: 120 EDVDEIIKLTDLQEDLEGNVKYEDFVK 146 >1I84-U nrPDB Length = 166 Score = 110 bits (275), Expect = 3e-25, Method: Composition-based stats. Identities = 41/151 (27%), Positives = 70/151 (46%), Gaps = 5/151 (3%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVD 77 E + ++ +EAF + D + G ID +L+ A+G + EE+ MI Sbjct: 13 SNVFSMFDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI---- 68 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 KEA+G I+F FL + +K+ D ++ I+ AF++ D D G I L+ + G Sbjct: 69 KEASGPINFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRF 128 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 T EE++ M D G V+ + ++ Sbjct: 129 TPEEIKNMWAAFPPDVAGNVDYKNICYVITH 159 >3TS5-B nrPDB Length = 161 Score = 110 bits (274), Expect = 5e-25, Method: Composition-based stats. Identities = 43/157 (27%), Positives = 86/157 (54%), Gaps = 5/157 (3%) Query: 14 SYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMI 73 + + L + QE++EAF + D + G ID+ +LK +LG P +E+ M+ Sbjct: 6 AQRATSNVFARLPQKLMQEMKEAFTMIDQNRDGFIDINDLKEMFSSLGRTPDDKELTAML 65 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 KEA G ++F FL++ + K++ D++E I AF +FD+ +T K++ + +K + + Sbjct: 66 ----KEAPGPLNFTMFLSIFSDKLSGTDSEETIRNAFGMFDELDTKKLNIEYIKDLLENM 121 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 G++ +E++ EA +G G+ + F+ ++K + Sbjct: 122 GDNFNKDEMRMTFKEAPVEG-GKFDYVRFVAMIKGSG 157 >1GGW-A nrPDB Length = 140 Score = 110 bits (274), Expect = 5e-25, Method: Composition-based stats. Identities = 42/135 (31%), Positives = 68/135 (50%), Gaps = 7/135 (5%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 ++AF LFD G+G I + +RA G P E I+E++ ++ FL V+ Sbjct: 8 KQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAE----ITEIESTLPAEVDMEQFLQVL 63 Query: 94 TQKM--AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + EE +K F++FD D TG I L+ V LGE L++EE+ E++ Sbjct: 64 NRPNGFDMPGDPEEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGVPV 123 Query: 152 DGDGEVNEEEFLKIM 166 DG VN +F++++ Sbjct: 124 -KDGMVNYHDFVQMI 137 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 36/62 (58%), Gaps = 1/62 (1%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 +E + F +FD D +G I V EL+ + +LG + EEM +++ V G ++++DF+ Sbjct: 76 EEFVKGFQVFDKDATGMIGVGELRYVLTSLGEKLSNEEMDELLKGVPV-KDGMVNYHDFV 134 Query: 91 AV 92 + Sbjct: 135 QM 136 Score = 38.0 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 +AF LFD TG+I ++ + G++ T E+ E+ EV+ E+FL++ Sbjct: 7 YKQAFSLFDRHGTGRIPKTSIGDLLRACGQNPTLAEITEIESTLPA----EVDMEQFLQV 62 Query: 166 MKK 168 + + Sbjct: 63 LNR 65 >1O1A-B nrPDB Length = 145 Score = 109 bits (273), Expect = 6e-25, Method: Composition-based stats. Identities = 41/145 (28%), Positives = 70/145 (48%), Gaps = 5/145 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGK 83 E + ++ +EAF + D + G ID +L+ A+G + EE+ MI KEA+G Sbjct: 1 FDETEIEDFKEAFTVIDQNADGIIDKDDLRETFAAMGRLNVKNEELDAMI----KEASGP 56 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 I+F FL + +K+ D ++ I+ AF++ D D G I L+ + G T EE++ Sbjct: 57 INFTVFLTMFGEKLKGADPEDVIMGAFKVLDPDGKGSIKKSFLEELLTTGGGRFTPEEIK 116 Query: 144 EMIDEADRDGDGEVNEEEFLKIMKK 168 M D G V+ + ++ Sbjct: 117 NMWAAFPPDVAGNVDYKNICYVITH 141 >3I5H-B nrPDB Length = 153 Score = 109 bits (272), Expect = 8e-25, Method: Composition-based stats. Identities = 41/144 (28%), Positives = 79/144 (54%), Gaps = 5/144 (3%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 + +L++ Q QE++EAF + D D G I +++LK +LG P +E+ M+ KE Sbjct: 7 RVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAML----KECP 62 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 G+++F FL + +K++ D ++ + AF +FD+D G I LK + +G++ + EE Sbjct: 63 GQLNFTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMGDNFSKEE 122 Query: 142 LQEMIDEADRDGDGEVNEEEFLKI 165 ++ + +A + N + + I Sbjct: 123 IKNVWKDAPLKNK-QFNYNKMVDI 145 Score = 34.9 bits (79), Expect = 0.016, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 38/109 (34%), Gaps = 33/109 (30%) Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA----- 149 + + +E+ +AF + D D G I ++LK + + LG D+EL M+ E Sbjct: 7 RVKLSQRQMQELKEAFTMIDQDRDGFIGMEDLKDMFSSLGRVPPDDELNAMLKECPGQLN 66 Query: 150 ----------------------------DRDGDGEVNEEEFLKIMKKTN 170 D DG G + E+ +++ Sbjct: 67 FTAFLTLFGEKVSGTDPEDALRNAFSMFDEDGQGFIPEDYLKDLLENMG 115 >4ORC-B nrPDB Length = 170 Score = 108 bits (270), Expect = 1e-24, Method: Composition-based stats. Identities = 42/155 (27%), Positives = 87/155 (56%), Gaps = 9/155 (5%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 D+ + + + F D D SG++ V+E +++ L P ++++I D + G Sbjct: 13 SHFDADEIKRLGKRFKKLDLDNSGSLSVEEF-MSLPELQQNPL---VQRVIDIFDTDGNG 68 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEE 141 ++ F +F+ ++Q + D ++++ AFR++D D+ G IS L +V + G +L D + Sbjct: 69 EVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLKMMVGNNLKDTQ 128 Query: 142 LQEMIDE----ADRDGDGEVNEEEFLKIMKKTNLY 172 LQ+++D+ AD+DGDG ++ EEF ++ +++ Sbjct: 129 LQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIH 163 Score = 56.1 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 50/109 (45%), Gaps = 7/109 (6%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELT--EDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 + F +K + + + D++Q++R AF ++D D G I EL ++ Sbjct: 58 VIDIFDTDGNGEVDFKEFIEGVSQFSVKGDKEQKLRFAFRIYDMDKDGYISNGELFQVLK 117 Query: 59 AL-GFEPRKEEMKKMISEV----DKEATGKISFNDFLAVMTQKMAEKDT 102 + G + ++++++ + DK+ G+ISF +F AV+ K Sbjct: 118 MMVGNNLKDTQLQQIVDKTIINADKDGDGRISFEEFCAVVGGLDIHKKM 166 >5H53-B nrPDB Length = 146 Score = 108 bits (269), Expect = 2e-24, Method: Composition-based stats. Identities = 39/145 (26%), Positives = 72/145 (49%), Gaps = 5/145 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG-FEPRKEEMKKMISEVDKEATGKIS 85 + Q QE +EAF + D + G ID ++L+ A+G + EE+ M+ KEA+G I+ Sbjct: 1 QTQIQEFKEAFTVIDQNRDGIIDKEDLRDTFAAMGRLNVKNEELDAMM----KEASGPIN 56 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 F FL + +K+ D ++ I AF++ D + G I + L+ + + + EE++ M Sbjct: 57 FTVFLTMFGEKLKGADPEDVITGAFKVLDPEGKGTIKKQFLEELLITQCDRFSQEEIKNM 116 Query: 146 IDEADRDGDGEVNEEEFLKIMKKTN 170 D G V+ + ++ + Sbjct: 117 WAAFSPDVGGNVDYKNICYVITHGD 141 Score = 32.6 bits (73), Expect = 0.085, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 30/67 (44%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 AF + D +G GTI + L+ + +EE+K M + + G + + + V+T Sbjct: 80 AFKVLDPEGKGTIKKQFLEELLITQCDRFSQEEIKNMWAAFSPDVGGNVDYKNICYVITH 139 Query: 96 KMAEKDT 102 A+ Sbjct: 140 GDAKDQE 146 >3JBH-C nrPDB Length = 156 Score = 106 bits (265), Expect = 5e-24, Method: Composition-based stats. Identities = 45/145 (31%), Positives = 78/145 (53%), Gaps = 3/145 (2%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +L + ++ RE F+++D +G G ID ++L +R+L +P +KK DK K Sbjct: 3 DLKAAEVEKAREHFEIYDWEGEGKIDARDLGDLLRSLDCKPTLAMVKKN-GGSDKRGEKK 61 Query: 84 ISFNDFLAVMTQKMAEKD--TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 ++ +FL + +Q EK+ T E+ ++ +++D E G + L V LGE LTD E Sbjct: 62 LTLEEFLPIFSQIKKEKEVGTLEDFMEGLKVYDKAENGTMLAAELAHVLLSLGERLTDIE 121 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIM 166 +E++ D D DG + E F+K + Sbjct: 122 CEEIMRVCDEDDDGFLKYEPFVKTI 146 >1DFK-Y nrPDB Length = 139 Score = 105 bits (261), Expect = 1e-23, Method: Composition-based stats. Identities = 43/144 (29%), Positives = 82/144 (56%), Gaps = 5/144 (3%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L + Q QE++EAF + D D G + +++K LG P +E+ M+ KEA G + Sbjct: 1 LPQKQIQEMKEAFSMIDVDRDGFVSKEDIKAISEQLGRAPDDKELTAML----KEAPGPL 56 Query: 85 SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +F FL++ + K++ D++E I AF +FD+ ET K++ + +K + +G++ +E++ Sbjct: 57 NFTMFLSIFSDKLSGTDSEETIRNAFAMFDEQETKKLNIEYIKDLLENMGDNFNKDEMRM 116 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 EA +G G+ + +F ++K Sbjct: 117 TFKEAPVEG-GKFDYVKFTAMIKG 139 >1ZMZ-A nrPDB Length = 98 Score = 105 bits (261), Expect = 2e-23, Method: Composition-based stats. Identities = 74/98 (75%), Positives = 92/98 (93%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 MAS F+K+N+AS+S ++++ PKPELTE+QKQE+REAFDLFD+DG+GTIDVKELKVAMRAL Sbjct: 1 MASNFKKANMASSSQRKRMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRAL 60 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMA 98 GFEP+KEE+KKMISE+DKE TGK++F DFL VMTQKM+ Sbjct: 61 GFEPKKEEIKKMISEIDKEGTGKMNFGDFLTVMTQKMS 98 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 29/80 (36%), Positives = 45/80 (56%) Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 + + ++ K+EI +AF LFD D TG I K LK LG EE+++MI E D Sbjct: 18 RMSPKPELTEEQKQEIREAFDLFDADGTGTIDVKELKVAMRALGFEPKKEEIKKMISEID 77 Query: 151 RDGDGEVNEEEFLKIMKKTN 170 ++G G++N +FL +M + Sbjct: 78 KEGTGKMNFGDFLTVMTQKM 97 >4JWQ-A nrPDB Length = 199 Score = 104 bits (260), Expect = 2e-23, Method: Composition-based stats. Identities = 39/142 (27%), Positives = 74/142 (52%), Gaps = 8/142 (5%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 Q+++ F D DG G I +LK + G + + ++ ++D + +G+I + +FL Sbjct: 58 QQLKTVFLYLDEDGKGNITKNQLKKGLENSGLKL-PQNFDVLLDQIDSDGSGRIDYTEFL 116 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA--NELGESLTDEELQE---M 145 A + +K+ I AFR+FD D G+I+ L + S+T +++ + M Sbjct: 117 AAALD--RKHLSKKLIYCAFRVFDVDNDGEITTAELAHILYNGNKKGSITQKDVNQVKKM 174 Query: 146 IDEADRDGDGEVNEEEFLKIMK 167 I E D++ DG+++ EF ++MK Sbjct: 175 IQEVDKNNDGKIDFYEFCEMMK 196 >3O4Y-A nrPDB Length = 196 Score = 103 bits (258), Expect = 3e-23, Method: Composition-based stats. Identities = 42/173 (24%), Positives = 83/173 (47%), Gaps = 9/173 (5%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTED-QKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 + F+ + K + + + D Q+++ AF D +G G I +L+ + Sbjct: 24 VLENFKNYALMLRFQKLAMTIIAQQSNDYDVQKLKAAFLHLDEEGKGNITKLQLRKGLER 83 Query: 60 LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETG 119 G ++ ++D + +G I + +FLA + + +K+ I AFR+FD D G Sbjct: 84 SGLMLPPN-FDLLLDQIDSDGSGNIDYTEFLAAAIDRR--QLSKKLIYCAFRVFDVDNDG 140 Query: 120 KISFKNLKRVA--NELGESLTDEELQE---MIDEADRDGDGEVNEEEFLKIMK 167 +I+ L V ++T+ ++ + MI E D++GDG+++ EF ++MK Sbjct: 141 EITTAELAHVLFNGNKRGNITERDVNQVKKMIREVDKNGDGKIDFYEFSEMMK 193 >3K21-A nrPDB Length = 191 Score = 103 bits (256), Expect = 5e-23, Method: Composition-based stats. Identities = 40/174 (22%), Positives = 87/174 (50%), Gaps = 11/174 (6%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTED-QKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 + F+ + K + + + D ++++ F + D DG G I ++LK + Sbjct: 21 VLENFKNYGLLLKFQKLAMTIIAQQSNDYDVEKLKSTFLVLDEDGKGYITKEQLKKGLEK 80 Query: 60 LGFE-PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDET 118 G + P ++ ++ ++D + +GKI + +F+A ++ +K+ I AFR+FD D Sbjct: 81 DGLKLPYNFDL--LLDQIDSDGSGKIDYTEFIAAALD--RKQLSKKLIYCAFRVFDVDND 136 Query: 119 GKISFKNLKRVA--NELGESLTDEEL---QEMIDEADRDGDGEVNEEEFLKIMK 167 G+I+ L + ++T ++ + MI + D++ DG+++ EF ++MK Sbjct: 137 GEITTAELAHILYNGNKKGNITQRDVNRVKRMIRDVDKNNDGKIDFHEFSEMMK 190 >2EC6-B nrPDB Length = 133 Score = 103 bits (256), Expect = 6e-23, Method: Composition-based stats. Identities = 43/138 (31%), Positives = 81/138 (58%), Gaps = 5/138 (3%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 QE++EAF + D + G ID+ +LK +LG P +E+ M+ KEA G ++F F Sbjct: 1 MQEMKEAFTMIDQNRDGFIDINDLKEEFSSLGRTPDDKELTAML----KEAPGPLNFTMF 56 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 L++ + K++ D++E I AF +FD+D T K++ + +K + +G++ +E++ EA Sbjct: 57 LSIFSDKLSGTDSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMRMTFKEA 116 Query: 150 DRDGDGEVNEEEFLKIMK 167 +G G+ + F+ ++K Sbjct: 117 PVEG-GKFDYVRFVAMIK 133 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++ +R AF +FD D + ++++ +K + +G K+EM+ E E GK + Sbjct: 68 DSEETIRNAFGMFDEDATKKLNIEYIKDLLENMGDNFNKDEMRMTFKEAPVEG-GKFDYV 126 Query: 88 DFLAV 92 F+A+ Sbjct: 127 RFVAM 131 >3IFK-A nrPDB Length = 90 Score = 100 bits (250), Expect = 3e-22, Method: Composition-based stats. Identities = 45/88 (51%), Positives = 61/88 (69%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 QLTEEQIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFR 111 I F +FL +M +KM + D++EEI +AFR Sbjct: 63 IDFPEFLTMMARKMKDTDSEEEIREAFR 90 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 29/66 (43%), Positives = 41/66 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 11 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 70 Query: 165 IMKKTN 170 +M + Sbjct: 71 MMARKM 76 >5B7X-A nrPDB Length = 156 Score = 98.9 bits (245), Expect = 1e-21, Method: Composition-based stats. Identities = 42/150 (28%), Positives = 79/150 (52%), Gaps = 2/150 (1%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDK 78 + + E Q++R+ F+ +D D G IDVK+L +R+LG P ++E+ I E Sbjct: 1 MSMEIEAPNANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAI 60 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKE-EILKAFRLFDDDETGKISFKNLKRVANELGESL 137 E F +M ++ ++ DT+E ++ KAF +FD D+ GKI +L +G+ + Sbjct: 61 EGE-TFQIEQFELIMEREQSKPDTREIKLRKAFEVFDQDKDGKIKASDLAHNLTTVGDKM 119 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 T EE++++ + +++ FLK++ Sbjct: 120 TKEEVEKVFSILGITMESDIDLATFLKLVA 149 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 1/77 (1%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + + A ++I F +D D GKI K L + LG + T++E+ I E Sbjct: 1 MSMEIEAPNANTQKIRDCFNFYDRDYDGKIDVKQLGTLIRSLGCAPTEDEVNSYIKEFAI 60 Query: 152 DGDGEVNEEEFLKIMKK 168 +G+ E+F IM++ Sbjct: 61 EGE-TFQIEQFELIMER 76 >3I5I-C nrPDB Length = 159 Score = 98.5 bits (244), Expect = 1e-21, Method: Composition-based stats. Identities = 41/148 (27%), Positives = 74/148 (50%), Gaps = 7/148 (4%) Query: 23 PELTEDQKQEVREAFDLFD-SDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA 80 +LT+D+ +EVRE FDLFD DG G +D ++ +R LG P + ++ + K Sbjct: 1 SQLTKDEIEEVREVFDLFDFWDGRDGDVDAAKVGDLLRCLGMNPTEAQVHQH-GGTKKMG 59 Query: 81 TGKISFNDFLAVMTQKMAEKDTK--EEILKAFRLFDDDETGKISFKNLKRVANELGESLT 138 + L + + ++ +E ++AF+ FD + G IS ++ V LGE +T Sbjct: 60 EKAYKLEEILPIYEEMSSKDTGTAADEFMEAFKTFDREGQGLISSAEIRNVLKMLGERIT 119 Query: 139 DEELQEMIDEAD--RDGDGEVNEEEFLK 164 +++ ++ D D DG + E+ +K Sbjct: 120 EDQCNDIFTFCDIREDIDGNIKYEDLMK 147 >5B8I-B nrPDB Length = 171 Score = 98.5 bits (244), Expect = 1e-21, Method: Composition-based stats. Identities = 42/149 (28%), Positives = 84/149 (56%), Gaps = 9/149 (6%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 ++ + + F D D SGTI+ E +++ + P +MI+ D++ G + F Sbjct: 18 EEVDRLWKRFMKLDRDKSGTIERDEF-LSLPQVSSNPLS---TRMIAIFDEDGGGDVDFQ 73 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMI 146 +F++ ++ ++ + +E++ AF+++D D G IS L V + G +L D +LQ+++ Sbjct: 74 EFVSGLSAFSSKGNKEEKLRFAFKVYDIDRDGFISNGELFIVLKMMVGSNLKDMQLQQIV 133 Query: 147 D----EADRDGDGEVNEEEFLKIMKKTNL 171 D EAD DGDG ++ EEF ++++ T++ Sbjct: 134 DKTIMEADLDGDGRISFEEFTRMVENTDV 162 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 32/77 (41%), Gaps = 4/77 (5%) Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 +++ + + + + K F D D++G I + L+ MI D Sbjct: 8 DIVSGSNFDHEEVDRLWKRFMKLDRDKSGTIERDEFLSLPQVSSNPLS----TRMIAIFD 63 Query: 151 RDGDGEVNEEEFLKIMK 167 DG G+V+ +EF+ + Sbjct: 64 EDGGGDVDFQEFVSGLS 80 >1N2D-A nrPDB Length = 148 Score = 97.0 bits (240), Expect = 3e-21, Method: Composition-based stats. Identities = 38/137 (27%), Positives = 73/137 (53%), Gaps = 6/137 (4%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK-ISFNDFLAV 92 ++ F LFD G G I L +RA+G+ P + ++ +I+ ++ + + Sbjct: 7 KDIFTLFDKKGQGAIAKDSLGDYLRAIGYNPTNQLVQDIINADSSLRDASSLTLDQITGL 66 Query: 93 MTQKMAEKD-----TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 + E D E+ +KAF++FD + TGK+S +L+ + LGE LTD E+ E++ Sbjct: 67 IEVNEKELDATTKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLK 126 Query: 148 EADRDGDGEVNEEEFLK 164 + D +GE++ ++F++ Sbjct: 127 GVEVDSNGEIDYKKFIE 143 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 38/66 (57%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 T+ + ++ +AF +FD + +G + V +L+ + LG + E+ +++ V+ ++ G+I Sbjct: 78 TKAKTEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEID 137 Query: 86 FNDFLA 91 + F+ Sbjct: 138 YKKFIE 143 >1Y1X-A nrPDB Length = 191 Score = 96.6 bits (239), Expect = 5e-21, Method: Composition-based stats. Identities = 31/138 (22%), Positives = 64/138 (46%), Gaps = 7/138 (5%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 + QE+ E F D+DGSG I V EL A+ + G +K++ DK +G+I+F+ Sbjct: 24 NDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDKNHSGEITFD 83 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 +F + + FR D G++ ++ G ++++ Q ++ Sbjct: 84 EF-------KDLHHFILSMREGFRKRDSSGDGRLDSNEVRAALLSSGYQVSEQTFQALMR 136 Query: 148 EADRDGDGEVNEEEFLKI 165 + DR G + ++++++ Sbjct: 137 KFDRQRRGSLGFDDYVEL 154 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 33/74 (44%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 V + +E+++ FR D D +G IS L + G + ++++ D+ Sbjct: 15 VYAPSARHMNDNQELMEWFRAVDTDGSGAISVPELNAALSSAGVPFSLATTEKLLHMYDK 74 Query: 152 DGDGEVNEEEFLKI 165 + GE+ +EF + Sbjct: 75 NHSGEITFDEFKDL 88 >5H7D-E nrPDB Length = 120 Score = 95.8 bits (237), Expect = 9e-21, Method: Composition-based stats. Identities = 33/68 (48%), Positives = 44/68 (64%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 +Q Q +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I F Sbjct: 53 NQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFP 112 Query: 88 DFLAVMTQ 95 +FL +M + Sbjct: 113 EFLTMMAR 120 Score = 86.6 bits (213), Expect = 5e-18, Method: Composition-based stats. Identities = 28/76 (36%), Positives = 45/76 (59%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + + + + + +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D D Sbjct: 45 LLAEAKKLNQIQAFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDAD 104 Query: 153 GDGEVNEEEFLKIMKK 168 G+G ++ EFL +M + Sbjct: 105 GNGTIDFPEFLTMMAR 120 Score = 35.3 bits (80), Expect = 0.012, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 + K+ S DK+ G I+ + VM + + + T+ E+ D D G I F Sbjct: 56 QAFKEAFSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEF 114 Query: 127 KRVA 130 + Sbjct: 115 LTMM 118 >4N5X-A nrPDB Length = 199 Score = 95.4 bits (236), Expect = 1e-20, Method: Composition-based stats. Identities = 32/135 (23%), Positives = 66/135 (48%), Gaps = 6/135 (4%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 +Q F D +G G +D+ EL+ +R LG ++ +K+ + D GK+ F Sbjct: 19 EQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFE 78 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 +F+ + KD ++++ AF+ D + GKI + + LG ++++++ + ++ Sbjct: 79 EFMKYL------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQ 132 Query: 148 EADRDGDGEVNEEEF 162 D DG V+ E+ Sbjct: 133 SIDVDGTMTVDWNEW 147 Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 36/81 (44%), Gaps = 1/81 (1%) Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 DF+ + T + + F+ D + G + L+ LG L + +++ Sbjct: 6 RDFV-LPTAASQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIF 64 Query: 147 DEADRDGDGEVNEEEFLKIMK 167 D + DG+++ EEF+K +K Sbjct: 65 TTGDVNKDGKLDFEEFMKYLK 85 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 35/62 (56%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D +++++ AF D + G I+ E+ +++ LG +++ + ++ +D + T + + Sbjct: 85 KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDW 144 Query: 87 ND 88 N+ Sbjct: 145 NE 146 Score = 39.6 bits (91), Expect = 8e-04, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 40/103 (38%), Gaps = 6/103 (5%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 + + +D+ G + + + E K F D ++ GK+ F+ + Sbjct: 24 YETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE-EKIFTTGDVNKDGKLDFEEFMK 82 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + +++++ D++ DG++ E ++ ++ L Sbjct: 83 YLKD-----HEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 120 >4ZCV-A nrPDB Length = 165 Score = 95.0 bits (235), Expect = 1e-20, Method: Composition-based stats. Identities = 32/135 (23%), Positives = 66/135 (48%), Gaps = 6/135 (4%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 +Q F D +G G +D+ EL+ +R LG ++ +K+ + D GK+ F Sbjct: 10 EQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKDGKLDFE 69 Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMID 147 +F+ + KD ++++ AF+ D + GKI + + LG ++++++ + ++ Sbjct: 70 EFMKYL------KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQ 123 Query: 148 EADRDGDGEVNEEEF 162 D DG V+ E+ Sbjct: 124 SIDVDGTMTVDWNEW 138 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 31/73 (42%) Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 + + F+ D + G + L+ LG L + +++ D + D Sbjct: 4 DACQDAEQPTRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNKD 63 Query: 155 GEVNEEEFLKIMK 167 G+++ EEF+K +K Sbjct: 64 GKLDFEEFMKYLK 76 Score = 45.7 bits (107), Expect = 9e-06, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 35/62 (56%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D +++++ AF D + G I+ E+ +++ LG +++ + ++ +D + T + + Sbjct: 76 KDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLTISEQQAELILQSIDVDGTMTVDW 135 Query: 87 ND 88 N+ Sbjct: 136 NE 137 Score = 39.2 bits (90), Expect = 9e-04, Method: Composition-based stats. Identities = 14/103 (13%), Positives = 40/103 (38%), Gaps = 6/103 (5%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 + + +D+ G + + + E K F D ++ GK+ F+ + Sbjct: 15 YETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAE-EKIFTTGDVNKDGKLDFEEFMK 73 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + +++++ D++ DG++ E ++ ++ L Sbjct: 74 YLKD-----HEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGL 111 >1SJJ-A nrPDB Length = 863 Score = 95.0 bits (235), Expect = 1e-20, Method: Composition-based stats. Identities = 25/112 (22%), Positives = 61/112 (54%), Gaps = 1/112 (0%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDK 78 ++++Q E R +F+ FD +G +D ++ + + ++G+ + E +++S VD Sbjct: 713 TRDAKGISQEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDP 772 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 G ++F F+ M+++ A+ DT ++++ +F++ D+ I+ L+R Sbjct: 773 NRMGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITVDELRREL 823 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 31/69 (44%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 ++ E +F FD +TG + ++ + +G ++ + E ++ D + G V Sbjct: 721 QEQMNEFRASFNHFDRKKTGMMDCEDFRACLISMGYNMGEAEFARIMSIVDPNRMGVVTF 780 Query: 160 EEFLKIMKK 168 + F+ M + Sbjct: 781 QAFIDFMSR 789 >2AMI-A nrPDB Length = 96 Score = 93.9 bits (232), Expect = 4e-20, Method: Composition-based stats. Identities = 60/94 (63%), Positives = 75/94 (79%), Gaps = 1/94 (1%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 +++ V S +K G + LTE+QKQE+REAFDLFD+DGSGTID KELKVAMRALGFE Sbjct: 4 SYKAKTVVSARRDQKKG-RVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFE 62 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKM 97 P+KEE+KKMISE+DK+ +G I F +FL +MT KM Sbjct: 63 PKKEEIKKMISEIDKDGSGTIDFEEFLTMMTAKM 96 Score = 75.0 bits (183), Expect = 2e-14, Method: Composition-based stats. Identities = 30/73 (41%), Positives = 43/73 (58%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + ++ K+EI +AF LFD D +G I K LK LG EE+++MI E D+DG Sbjct: 20 GRVGLTEEQKQEIREAFDLFDTDGSGTIDAKELKVAMRALGFEPKKEEIKKMISEIDKDG 79 Query: 154 DGEVNEEEFLKIM 166 G ++ EEFL +M Sbjct: 80 SGTIDFEEFLTMM 92 Score = 25.7 bits (55), Expect = 9.5, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 16/29 (55%) Query: 139 DEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +E++E D D DG G ++ +E M+ Sbjct: 29 KQEIREAFDLFDTDGSGTIDAKELKVAMR 57 >5COC-A nrPDB Length = 130 Score = 93.5 bits (231), Expect = 4e-20, Method: Composition-based stats. Identities = 35/72 (48%), Positives = 46/72 (63%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 E+ E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I F Sbjct: 59 EECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 118 Query: 87 NDFLAVMTQKMA 98 +FL +M +KM Sbjct: 119 PEFLTMMARKMK 130 Score = 84.2 bits (207), Expect = 2e-17, Method: Composition-based stats. Identities = 29/71 (40%), Positives = 43/71 (60%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 ++ E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ Sbjct: 59 EECIAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDF 118 Query: 160 EEFLKIMKKTN 170 EFL +M + Sbjct: 119 PEFLTMMARKM 129 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E K+ S DK+ G I+ + VM + + + T+ E+ D D G I F Sbjct: 63 AEFKEAFSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEF 121 Query: 127 KRVA 130 + Sbjct: 122 LTMM 125 >4OCI-A nrPDB Length = 146 Score = 93.5 bits (231), Expect = 4e-20, Method: Composition-based stats. Identities = 32/137 (23%), Positives = 66/137 (48%), Gaps = 2/137 (1%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 + ++++E+F LFD DG G + + E + +R LG + + K +S+ Sbjct: 2 QKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSK--VRGMSY 59 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 F + +Q + K+EI A + D D+ G I L+R+ + +G+++ +E+ ++ Sbjct: 60 ELFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILSTIGDNMEQKEITDLF 119 Query: 147 DEADRDGDGEVNEEEFL 163 D G V ++F+ Sbjct: 120 TFMGIDEQGVVKVDDFI 136 Score = 29.5 bits (65), Expect = 0.66, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 34/104 (32%), Gaps = 35/104 (33%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE----------------------- 135 + E++ ++F LFD D G ++ + + LG Sbjct: 1 MQKHNEDLKESFLLFDGDGDGYLTLNEFESLVRVLGVVMETSAIASTYNSNSKVRGMSYE 60 Query: 136 ------------SLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 S +E++ I+ D+D G + E +I+ Sbjct: 61 LFTSCFSQLKTKSFNKDEIKTAINVLDKDKKGFIPAIELRRILS 104 >2I08-A nrPDB Length = 78 Score = 93.1 bits (230), Expect = 5e-20, Method: Composition-based stats. Identities = 36/75 (48%), Positives = 49/75 (65%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LTE+Q E +EAF L+D DG GTI KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 QLTEEQIAEFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMA 98 I F +FL +M + M Sbjct: 63 IDFPEFLTMMARIMK 77 Score = 79.2 bits (194), Expect = 8e-16, Method: Composition-based stats. Identities = 29/68 (42%), Positives = 41/68 (60%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF L+D D G I+ K L V LG + T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 11 EFKEAFSLYDKDGDGTITTKELGTVMRSLGLNPTEAELQDMINEVDADGNGTIDFPEFLT 70 Query: 165 IMKKTNLY 172 +M + Y Sbjct: 71 MMARIMKY 78 Score = 34.2 bits (77), Expect = 0.031, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E K+ S DK+ G I+ + VM + + T+ E+ D D G I F Sbjct: 10 AEFKEAFSLYDKDGDGTITTKELGTVM-RSLGLNPTEAELQDMINEVDADGNGTIDFPEF 68 Query: 127 KRVA 130 + Sbjct: 69 LTMM 72 >4D1E-A nrPDB Length = 876 Score = 92.7 bits (229), Expect = 7e-20, Method: Composition-based stats. Identities = 28/112 (25%), Positives = 62/112 (55%), Gaps = 1/112 (0%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDK 78 +T++Q E R +F+ FD +G +D ++ + + ++G++ + E ++++ VD Sbjct: 726 TRDAKGITQEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDP 785 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 G ++F F+ MT++ A+ DT E+++ +FR+ D+ I + L+R Sbjct: 786 NGQGTVTFQSFIDFMTRETADTDTAEQVIASFRILASDKP-YILAEELRREL 836 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 30/69 (43%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 ++ E +F FD + G + ++ + +G L + E ++ D +G G V Sbjct: 734 QEQMNEFRASFNHFDRRKNGLMDHEDFRACLISMGYDLGEAEFARIMTLVDPNGQGTVTF 793 Query: 160 EEFLKIMKK 168 + F+ M + Sbjct: 794 QSFIDFMTR 802 >2RO8-A nrPDB Length = 79 Score = 91.9 bits (227), Expect = 1e-19, Method: Composition-based stats. Identities = 36/77 (46%), Positives = 50/77 (64%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +LT++Q E +EAF LFD DG G I KEL MR+LG P + E++ MI+EVD + G Sbjct: 3 QLTDEQISEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGT 62 Query: 84 ISFNDFLAVMTQKMAEK 100 I F +FL +M +KM + Sbjct: 63 IDFPEFLNLMARKMKDT 79 Score = 77.7 bits (190), Expect = 3e-15, Method: Composition-based stats. Identities = 29/67 (43%), Positives = 41/67 (61%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 10 SEFKEAFSLFDKDGDGCITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFL 69 Query: 164 KIMKKTN 170 +M + Sbjct: 70 NLMARKM 76 >5W1A-B nrPDB Length = 155 Score = 89.6 bits (221), Expect = 6e-19, Method: Composition-based stats. Identities = 40/147 (27%), Positives = 72/147 (48%), Gaps = 6/147 (4%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 ++ + + + V F++ S G G ID +L A+RAL P ++K+ K K Sbjct: 3 DVPKREVENVEFVFEVMGSPGEG-IDAVDLGDALRALNLNPTLALIEKL-GGTKKRNEKK 60 Query: 84 ISFNDFLAVMTQ--KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 I ++FL + +Q K E+ E+ ++ +L+D +E G + L+ LGESL DE+ Sbjct: 61 IKLDEFLPIYSQVKKEKEQGCYEDFIECLKLYDKEENGTMLLAELQHALLALGESLDDEQ 120 Query: 142 LQEMIDEA--DRDGDGEVNEEEFLKIM 166 ++ + + D +G + FL M Sbjct: 121 VETLFADCMDPEDDEGFIPYSPFLARM 147 >1M39-A nrPDB Length = 89 Score = 88.9 bits (219), Expect = 9e-19, Method: Composition-based stats. Identities = 77/89 (86%), Positives = 86/89 (96%) Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 ++F DFL VMTQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQ Sbjct: 1 MNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQ 60 Query: 144 EMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 EMIDEADRDGDGEV+E+EFL+IMKKT+LY Sbjct: 61 EMIDEADRDGDGEVSEQEFLRIMKKTSLY 89 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 27/69 (39%), Positives = 43/69 (62%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D K+E+ +AF LFD D +G I K LK + LG EE+++MI E D++ G++S Sbjct: 17 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSE 76 Query: 87 NDFLAVMTQ 95 +FL +M + Sbjct: 77 QEFLRIMKK 85 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 39/79 (49%), Gaps = 1/79 (1%) Query: 53 LKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRL 112 L V + + + KEE+ K D + TGKISF + L + +++ E T EE+ + Sbjct: 7 LTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDE 65 Query: 113 FDDDETGKISFKNLKRVAN 131 D D G++S + R+ Sbjct: 66 ADRDGDGEVSEQEFLRIMK 84 >3AAJ-A nrPDB Length = 167 Score = 88.9 bits (219), Expect = 1e-18, Method: Composition-based stats. Identities = 32/125 (25%), Positives = 54/125 (43%), Gaps = 14/125 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 + S F + N A ++ G +T+ Q F +D D SG ID ELK A+ Sbjct: 46 IISMFDRENKAGVNFSEFTGVWKYITDWQN-----VFRTYDRDNSGMIDKNELKQALS-- 98 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 G+ + +I + D++ G+I+F+DF+ + + FR +D D+ G Sbjct: 99 GYRLSDQFHDILIRKFDRQGRGQIAFDDFIQGC-------IVLQRLTDIFRRYDTDQDGW 151 Query: 121 ISFKN 125 I Sbjct: 152 IQVSY 156 Score = 80.8 bits (198), Expect = 3e-16, Method: Composition-based stats. Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 10/130 (7%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKE-EMKKMISEVDKEATGKISFNDFLAVMT 94 F D D SG I EL+ A+ + P ++ +IS D+E ++F++F V Sbjct: 9 VFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTGVWK 68 Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 + FR +D D +G I LK+ + G L+D+ +I + DR G Sbjct: 69 YIT-------DWQNVFRTYDRDNSGMIDKNELKQALS--GYRLSDQFHDILIRKFDRQGR 119 Query: 155 GEVNEEEFLK 164 G++ ++F++ Sbjct: 120 GQIAFDDFIQ 129 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 25/61 (40%), Gaps = 1/61 (1%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANE-LGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + F+ D D +G IS L++ + ++ +I DR+ VN EF Sbjct: 6 LWNVFQRVDKDRSGVISDTELQQALSNGTWTPFNPVTVRSIISMFDRENKAGVNFSEFTG 65 Query: 165 I 165 + Sbjct: 66 V 66 >2BEC-A nrPDB Length = 202 Score = 88.5 bits (218), Expect = 1e-18, Method: Composition-based stats. Identities = 41/187 (21%), Positives = 79/187 (42%), Gaps = 25/187 (13%) Query: 6 RKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR 65 R S+ A + + ++ + F D + G + +L+ AL P Sbjct: 4 RSSHAAVIPDGDSIRRETGFSQASLLRLHHRFRALDRNKKGYLSRMDLQQI-GALAVNPL 62 Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKD----------------TKEEILKA 109 ++I + + ++ F F+ V+ +D + ++ A Sbjct: 63 G---DRIIESFFPDGSQRVDFPGFVRVLAHFRPVEDEDTETQDPKKPEPLNSRRNKLHYA 119 Query: 110 FRLFDDDETGKISFKNLKRVAN-ELGESLTDEELQEM----IDEADRDGDGEVNEEEFLK 164 F+L+D D GKIS + +V +G +T+E+L+ + + EAD DGDG V+ EF K Sbjct: 120 FQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEADEDGDGAVSFVEFTK 179 Query: 165 IMKKTNL 171 ++K ++ Sbjct: 180 SLEKMDV 186 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 24/92 (26%), Positives = 46/92 (50%), Gaps = 5/92 (5%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL-GFEPRKEEMKKM----ISEV 76 KPE ++ ++ AF L+D D G I E+ +R + G + +E+++ + + E Sbjct: 105 KPEPLNSRRNKLHYAFQLYDLDRDGKISRHEMLQVLRLMVGVQVTEEQLENIADRTVQEA 164 Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILK 108 D++ G +SF +F + + E+ ILK Sbjct: 165 DEDGDGAVSFVEFTKSLEKMDVEQKMSIRILK 196 >2LV7-A nrPDB Length = 100 Score = 86.9 bits (214), Expect = 4e-18, Method: Composition-based stats. Identities = 27/72 (37%), Positives = 49/72 (68%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 ++ ED+ +E+REAF +FD DG+G I +EL AMR+LG+ P + E++ +I +D + G Sbjct: 28 VDIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDG 87 Query: 83 KISFNDFLAVMT 94 ++ F +F+ ++ Sbjct: 88 QVDFEEFVTLLG 99 Score = 74.6 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 27/70 (38%), Positives = 40/70 (57%) Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 +D EEI +AF++FD D G IS + L LG + EL+ +I D DGDG+ Sbjct: 29 DIPEDELEEIREAFKVFDRDGNGFISKQELGTAMRSLGYMPNEVELEVIIQRLDMDGDGQ 88 Query: 157 VNEEEFLKIM 166 V+ EEF+ ++ Sbjct: 89 VDFEEFVTLL 98 Score = 35.3 bits (80), Expect = 0.012, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 27/64 (42%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 EE+++ D++ G IS + M + + + E+ + D D G++ F+ Sbjct: 36 EEIREAFKVFDRDGNGFISKQELGTAM-RSLGYMPNEVELEVIIQRLDMDGDGQVDFEEF 94 Query: 127 KRVA 130 + Sbjct: 95 VTLL 98 >4Q57-A nrPDB Length = 65 Score = 86.2 bits (212), Expect = 6e-18, Method: Composition-based stats. Identities = 32/65 (49%), Positives = 41/65 (63%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 E +EAF LFD DG GTI KEL MR+LG P + E++ MI+EVD + G I F +F Sbjct: 1 IAEFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 90 LAVMT 94 L +M Sbjct: 61 LTMMA 65 Score = 78.5 bits (192), Expect = 1e-15, Method: Composition-based stats. Identities = 29/63 (46%), Positives = 40/63 (63%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G I+ K L V LG++ T+ ELQ+MI+E D DG+G ++ EFL Sbjct: 3 EFKEAFSLFDKDGDGTITTKELGTVMRSLGQNPTEAELQDMINEVDADGNGTIDFPEFLT 62 Query: 165 IMK 167 +M Sbjct: 63 MMA 65 Score = 34.5 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E K+ S DK+ G I+ + VM + + + T+ E+ D D G I F Sbjct: 2 AEFKEAFSLFDKDGDGTITTKELGTVM-RSLGQNPTEAELQDMINEVDADGNGTIDFPEF 60 Query: 127 KRVA 130 + Sbjct: 61 LTMM 64 >1FW4-A nrPDB Length = 71 Score = 85.8 bits (211), Expect = 9e-18, Method: Composition-based stats. Identities = 39/68 (57%), Positives = 50/68 (73%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 + D++EEI +AFR+FD D G IS L+ V LGE LTDEE+ EMI EAD DGDG+VN Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVN 60 Query: 159 EEEFLKIM 166 EEF+++M Sbjct: 61 YEEFVQMM 68 Score = 71.5 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 27/67 (40%), Positives = 44/67 (65%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF +FD DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 3 DSEEEIREAFRVFDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 62 Query: 88 DFLAVMT 94 +F+ +MT Sbjct: 63 EFVQMMT 69 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+++ DK+ G IS + VMT + EK T EE+ + R D D G+++++ Sbjct: 4 SEEEIREAFRVFDKDGNGYISAAELRHVMTN-LGEKLTDEEVDEMIREADIDGDGQVNYE 62 Query: 125 NLKRVANE 132 ++ Sbjct: 63 EFVQMMTA 70 Score = 27.2 bits (59), Expect = 4.2, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 20/36 (55%) Query: 135 ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 ++ ++EE++E D+DG+G ++ E +M Sbjct: 1 DTDSEEEIREAFRVFDKDGNGYISAAELRHVMTNLG 36 >2N8Y-A nrPDB Length = 153 Score = 85.4 bits (210), Expect = 1e-17, Method: Composition-based stats. Identities = 30/113 (26%), Positives = 62/113 (54%), Gaps = 6/113 (5%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF-----EPRKEEMKKMISEVD 77 ++++Q E R +F+ FD D SGT+ +E K + +LG+ + E +++S VD Sbjct: 2 SSISQEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVD 61 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 G ++F F+ M+++ A+ DT ++++ +F++ D+ I+ L+R Sbjct: 62 PNRLGVVTFQAFIDFMSRETADTDTADQVMASFKILAGDKN-YITMDELRREL 113 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 29/74 (39%), Gaps = 5/74 (6%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL-----TDEELQEMIDEADRDGD 154 ++ E +F FD D +G + + K LG + + E ++ D + Sbjct: 6 QEQMNEFRASFNHFDRDHSGTLGPEEFKACLISLGYDIGNDPQGEAEFARIMSIVDPNRL 65 Query: 155 GEVNEEEFLKIMKK 168 G V + F+ M + Sbjct: 66 GVVTFQAFIDFMSR 79 >2KN2-A nrPDB Length = 92 Score = 85.4 bits (210), Expect = 1e-17, Method: Composition-based stats. Identities = 37/68 (54%), Positives = 51/68 (75%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 + D +EE+ +AF++FD D+ G IS L+ V LGE LTDEE+++MI EAD DGDG+VN Sbjct: 4 DTDAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVN 63 Query: 159 EEEFLKIM 166 EEF+K+M Sbjct: 64 YEEFVKMM 71 Score = 72.3 bits (176), Expect = 1e-13, Method: Composition-based stats. Identities = 24/67 (35%), Positives = 43/67 (64%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+++MI E D + G++++ Sbjct: 6 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 65 Query: 88 DFLAVMT 94 +F+ +M Sbjct: 66 EFVKMMM 72 >1F55-A nrPDB Length = 77 Score = 84.2 bits (207), Expect = 2e-17, Method: Composition-based stats. Identities = 30/74 (40%), Positives = 49/74 (66%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 LTE+Q E +EAF LFD D +G+I EL MR+LG P + E+ +++E+D + Sbjct: 2 SNLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNH 61 Query: 83 KISFNDFLAVMTQK 96 +I F++FLA+M+++ Sbjct: 62 QIEFSEFLALMSRQ 75 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 24/64 (37%), Positives = 37/64 (57%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 E +AF LFD D G IS L V LG S ++ E+ ++++E D DG+ ++ EFL Sbjct: 11 EFKEAFALFDKDNNGSISSSELATVMRSLGLSPSEAEVNDLMNEIDVDGNHQIEFSEFLA 70 Query: 165 IMKK 168 +M + Sbjct: 71 LMSR 74 Score = 26.1 bits (56), Expect = 8.2, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 20/39 (51%), Gaps = 3/39 (7%) Query: 136 SLTDE---ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 +LT+E E +E D+D +G ++ E +M+ L Sbjct: 3 NLTEEQIAEFKEAFALFDKDNNGSISSSELATVMRSLGL 41 >2KZ2-A nrPDB Length = 94 Score = 83.5 bits (205), Expect = 5e-17, Method: Composition-based stats. Identities = 39/74 (52%), Positives = 50/74 (67%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 M + D++EEI +AFR+ D D G IS L+ V LGE LTDEE+ EMI EAD D Sbjct: 18 FQSLMKDTDSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADID 77 Query: 153 GDGEVNEEEFLKIM 166 GDG+VN EEF+++M Sbjct: 78 GDGQVNYEEFVQMM 91 Score = 67.7 bits (164), Expect = 3e-12, Method: Composition-based stats. Identities = 26/67 (38%), Positives = 43/67 (64%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E+REAF + D DG+G I EL+ M LG + EE+ +MI E D + G++++ Sbjct: 26 DSEEEIREAFRVEDKDGNGYISAAELRHVMTNLGEKLTDEEVDEMIREADIDGDGQVNYE 85 Query: 88 DFLAVMT 94 +F+ +MT Sbjct: 86 EFVQMMT 92 Score = 33.8 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+++ DK+ G IS + VMT + EK T EE+ + R D D G+++++ Sbjct: 27 SEEEIREAFRVEDKDGNGYISAAELRHVMT-NLGEKLTDEEVDEMIREADIDGDGQVNYE 85 Query: 125 NLKRVANE 132 ++ Sbjct: 86 EFVQMMTA 93 >5VLN-A nrPDB Length = 120 Score = 82.7 bits (203), Expect = 7e-17, Method: Composition-based stats. Identities = 40/113 (35%), Positives = 57/113 (50%), Gaps = 17/113 (15%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEV 76 +LTE+QK E + AFD+F G+I KEL MR LG P EE+++MI EV Sbjct: 5 YKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV 64 Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 D++ +G + F++FL +M + M DD GK L+RV Sbjct: 65 DEDGSGTVDFDEFLVMMVRSMK----------------DDSKGKFKRPTLRRV 101 Score = 77.7 bits (190), Expect = 2e-15, Method: Composition-based stats. Identities = 33/72 (45%), Positives = 44/72 (61%), Gaps = 1/72 (1%) Query: 100 KDTKEEILKAFRLFD-DDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 ++ K E AF +F E G IS K L +V LG++ T EELQEMIDE D DG G V+ Sbjct: 14 EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 73 Query: 159 EEEFLKIMKKTN 170 +EFL +M ++ Sbjct: 74 FDEFLVMMVRSM 85 >2M5E-A nrPDB Length = 73 Score = 82.3 bits (202), Expect = 9e-17, Method: Composition-based stats. Identities = 37/71 (52%), Positives = 52/71 (73%) Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 M E+D++EE+++AF++FD D G IS L+ V LGE LTD+E+ EMI EAD DGDG Sbjct: 1 MKEQDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGH 60 Query: 157 VNEEEFLKIMK 167 +N EEF+++M Sbjct: 61 INYEEFVRMMV 71 Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 25/68 (36%), Positives = 42/68 (61%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D ++E+ EAF +FD DG+G I EL+ M LG + +E+ +MI E D + G I++ Sbjct: 4 QDSEEELIEAFKVFDRDGNGLISAAELRHVMTNLGEKLTDDEVDEMIREADIDGDGHINY 63 Query: 87 NDFLAVMT 94 +F+ +M Sbjct: 64 EEFVRMMV 71 Score = 33.0 bits (74), Expect = 0.068, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+ + D++ G IS + VMT + EK T +E+ + R D D G I+++ Sbjct: 6 SEEELIEAFKVFDRDGNGLISAAELRHVMTN-LGEKLTDDEVDEMIREADIDGDGHINYE 64 Query: 125 NLKRVA 130 R+ Sbjct: 65 EFVRMM 70 >2KSZ-A nrPDB Length = 76 Score = 82.3 bits (202), Expect = 1e-16, Method: Composition-based stats. Identities = 34/72 (47%), Positives = 50/72 (69%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+Q + +EAF LFD DG G I V+EL +R+L P +EE++ MISEVD + G I Sbjct: 4 LSEEQIVDFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTI 63 Query: 85 SFNDFLAVMTQK 96 F++FL++M +K Sbjct: 64 EFDEFLSLMAKK 75 Score = 72.3 bits (176), Expect = 9e-14, Method: Composition-based stats. Identities = 28/64 (43%), Positives = 40/64 (62%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + +AF LFD D G I+ + L V L ++ T+EELQ+MI E D DG+G + +EFL Sbjct: 11 DFKEAFGLFDKDGDGCITVEELATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFLS 70 Query: 165 IMKK 168 +M K Sbjct: 71 LMAK 74 Score = 34.2 bits (77), Expect = 0.029, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 68 EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLK 127 + K+ DK+ G I+ + LA + + + + T+EE+ D D G I F Sbjct: 11 DFKEAFGLFDKDGDGCITVEE-LATVIRSLDQNPTEEELQDMISEVDADGNGTIEFDEFL 69 Query: 128 RVA 130 + Sbjct: 70 SLM 72 >5MWC-D nrPDB Length = 311 Score = 81.9 bits (201), Expect = 1e-16, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 40/69 (57%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 +EE+ + FR FD D G I + + GE LTDE+ E+ ++D D +G ++ +EF Sbjct: 150 EEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEF 209 Query: 163 LKIMKKTNL 171 LK+++ L Sbjct: 210 LKMVENVQL 218 Score = 75.8 bits (185), Expect = 1e-14, Method: Composition-based stats. Identities = 20/65 (30%), Positives = 36/65 (55%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++E+ E F FD DG G ID +E +R G + E+ ++ + D + G+I F++ Sbjct: 149 SEEELSECFRTFDKDGDGFIDREEFGGIIRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDE 208 Query: 89 FLAVM 93 FL ++ Sbjct: 209 FLKMV 213 Score = 47.6 bits (112), Expect = 2e-06, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 P +EE+ + DK+ G I +F ++ + E+ T E+ + F D D+ G+I F Sbjct: 148 PSEEELSECFRTFDKDGDGFIDREEFGGII-RLTGEQLTDEDPDEIFGDSDTDKNGRIDF 206 Query: 124 KNLKRVANELGESLTD 139 ++ + S+ D Sbjct: 207 DEFLKMVENVQLSMAD 222 Score = 35.3 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 21/34 (61%) Query: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 ++EEL E D+DGDG ++ EEF I++ T Sbjct: 148 PSEEELSECFRTFDKDGDGFIDREEFGGIIRLTG 181 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 29/93 (31%), Gaps = 14/93 (15%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQK--QEVREAFDLFDSDGSGTIDVKELKVA----- 56 TF K + G LT +Q ++ E F D+D +G ID E Sbjct: 159 TFDKDGDGFIDREEFGGI-IRLTGEQLTDEDPDEIFGDSDTDKNGRIDFDEFLKMVENVQ 217 Query: 57 ------MRALGFEPRKEEMKKMISEVDKEATGK 83 R+ P + + + GK Sbjct: 218 LSMADWCRSKMACPNDKTLISTLKWSYTTGNGK 250 >2RO9-A nrPDB Length = 69 Score = 81.2 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 38/66 (57%), Positives = 50/66 (75%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D++EE+ +AFR+FD D+ G IS L+ V LGE LTDEE+ EMI EAD DGDG++N E Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 161 EFLKIM 166 EF+K+M Sbjct: 61 EFVKVM 66 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 26/67 (38%), Positives = 42/67 (62%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+ +MI E D + G+I++ Sbjct: 1 DSEEELKEAFRVFDKDQNGFISAAELRHVMTNLGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 88 DFLAVMT 94 +F+ VM Sbjct: 61 EFVKVMM 67 Score = 33.8 bits (76), Expect = 0.036, Method: Composition-based stats. Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+K+ DK+ G IS + VMT + EK T EE+ + R D D G+I+++ Sbjct: 2 SEEELKEAFRVFDKDQNGFISAAELRHVMTN-LGEKLTDEEVDEMIREADVDGDGQINYE 60 Query: 125 NLKRVA 130 +V Sbjct: 61 EFVKVM 66 >2E30-A nrPDB Length = 195 Score = 81.2 bits (199), Expect = 2e-16, Method: Composition-based stats. Identities = 40/186 (21%), Positives = 81/186 (43%), Gaps = 24/186 (12%) Query: 6 RKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPR 65 R S + ++ + + Q + F D +GT+ ++ + L P Sbjct: 4 RASTLLRDEELEEIKKETGFSHSQITRLYSRFTSLDKGENGTLSREDFQRI-PELAINPL 62 Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKE---------------EILKAF 110 ++I+ E +++F F+ + +D ++ ++ AF Sbjct: 63 G---DRIINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAF 119 Query: 111 RLFDDDETGKISFKNLKRVANEL-GESLTDEEL----QEMIDEADRDGDGEVNEEEFLKI 165 RL+D D+ KIS L +V + G +++DE+L I EAD+DGD ++ EF+K+ Sbjct: 120 RLYDLDKDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKV 179 Query: 166 MKKTNL 171 ++K ++ Sbjct: 180 LEKVDV 185 Score = 48.4 bits (114), Expect = 1e-06, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 43/124 (34%), Gaps = 22/124 (17%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQE-----------------VREAFDLFDSD 43 + + F +++ + + E + AF L+D D Sbjct: 66 IINAFFPEGEDQVNFRGFMRTLAHFRPIEDNEKSKDVNGPEPLNSRSNKLHFAFRLYDLD 125 Query: 44 GSGTIDVKELKVAMRAL-GFEPRKEEM----KKMISEVDKEATGKISFNDFLAVMTQKMA 98 I EL +R + G E++ + I E D++ ISF +F+ V+ + Sbjct: 126 KDEKISRDELLQVLRMMVGVNISDEQLGSIADRTIQEADQDGDSAISFTEFVKVLEKVDV 185 Query: 99 EKDT 102 E+ Sbjct: 186 EQKM 189 >2N7L-C nrPDB Length = 141 Score = 80.8 bits (198), Expect = 3e-16, Method: Composition-based stats. Identities = 33/86 (38%), Positives = 50/86 (58%), Gaps = 1/86 (1%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEV 76 +LTE+QK E + AFD+F G+I KEL MR LG P EE+++MI EV Sbjct: 20 YKAAVEQLTEEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEV 79 Query: 77 DKEATGKISFNDFLAVMTQKMAEKDT 102 D++ +G + F++FL +M + M + Sbjct: 80 DEDGSGTVDFDEFLVMMVRXMKDDSE 105 Score = 77.7 bits (190), Expect = 2e-15, Method: Composition-based stats. Identities = 33/72 (45%), Positives = 43/72 (59%), Gaps = 1/72 (1%) Query: 100 KDTKEEILKAFRLFD-DDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 ++ K E AF +F E G IS K L +V LG++ T EELQEMIDE D DG G V+ Sbjct: 29 EEQKNEFKAAFDIFVLGAEDGSISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 88 Query: 159 EEEFLKIMKKTN 170 +EFL +M + Sbjct: 89 FDEFLVMMVRXM 100 >2ROB-A nrPDB Length = 70 Score = 80.4 bits (197), Expect = 4e-16, Method: Composition-based stats. Identities = 37/66 (56%), Positives = 50/66 (75%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 D +EE+ +AF++FD D+ G IS L+ V LGE LTDEE+++MI EAD DGDG+VN E Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 161 EFLKIM 166 EF+K+M Sbjct: 61 EFVKMM 66 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 24/67 (35%), Positives = 43/67 (64%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D ++E++EAF +FD D +G I EL+ M LG + EE+++MI E D + G++++ Sbjct: 1 DAEEELKEAFKVFDKDQNGYISASELRHVMINLGEKLTDEEVEQMIKEADLDGDGQVNYE 60 Query: 88 DFLAVMT 94 +F+ +M Sbjct: 61 EFVKMMM 67 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 36/68 (52%), Gaps = 1/68 (1%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 +EE+K+ DK+ G IS ++ VM + EK T EE+ + + D D G+++++ Sbjct: 3 EEELKEAFKVFDKDQNGYISASELRHVMIN-LGEKLTDEEVEQMIKEADLDGDGQVNYEE 61 Query: 126 LKRVANEL 133 ++ + Sbjct: 62 FVKMMMTV 69 >5Z1Q-A nrPDB Length = 95 Score = 80.0 bits (196), Expect = 4e-16, Method: Composition-based stats. Identities = 43/82 (52%), Positives = 64/82 (78%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD 77 K + EL+E+QKQE++EAFDLFD++ +G+ID ELKVAMRALGF+ +K E+ ++++E D Sbjct: 14 KKRVRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYD 73 Query: 78 KEATGKISFNDFLAVMTQKMAE 99 +E G I F+DFL +MT+K+ Sbjct: 74 REGNGYIGFDDFLDIMTEKIKN 95 Score = 63.1 bits (152), Expect = 6e-11, Method: Composition-based stats. Identities = 26/73 (35%), Positives = 45/73 (61%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 ++ ++ K+EI +AF LFD ++TG I + LK LG + E+ E+++E DR+G Sbjct: 17 VRQELSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREG 76 Query: 154 DGEVNEEEFLKIM 166 +G + ++FL IM Sbjct: 77 NGYIGFDDFLDIM 89 Score = 26.5 bits (57), Expect = 7.0, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 20/41 (48%), Gaps = 1/41 (2%) Query: 127 KRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 KRV EL E +E++E D D + G ++ E M+ Sbjct: 15 KRVRQELSEE-QKQEIKEAFDLFDTNKTGSIDYHELKVAMR 54 >1TNP-A nrPDB Length = 90 Score = 80.0 bits (196), Expect = 5e-16, Method: Composition-based stats. Identities = 35/75 (46%), Positives = 49/75 (65%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+ E + AFD+FD+DG G I KEL MR LG P KEE+ +I EVD++ +G I Sbjct: 14 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 73 Query: 85 SFNDFLAVMTQKMAE 99 F +FL +M ++M E Sbjct: 74 DFEEFLVMMVRQMKE 88 Score = 73.8 bits (180), Expect = 3e-14, Method: Composition-based stats. Identities = 29/75 (38%), Positives = 41/75 (54%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + ++ E AF +FD D G IS K L V LG++ T EEL +I+E D DG Sbjct: 10 ARAFLSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDG 69 Query: 154 DGEVNEEEFLKIMKK 168 G ++ EEFL +M + Sbjct: 70 SGTIDFEEFLVMMVR 84 Score = 30.3 bits (67), Expect = 0.42, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 23/64 (35%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E K D + G IS + VM KEE+ D+D +G I F+ Sbjct: 20 AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPT-KEELDAIIEEVDEDGSGTIDFEEF 78 Query: 127 KRVA 130 + Sbjct: 79 LVMM 82 >1TRF-A nrPDB Length = 76 Score = 79.2 bits (194), Expect = 8e-16, Method: Composition-based stats. Identities = 34/74 (45%), Positives = 48/74 (64%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+ E + AFD+FD+DG G I KEL MR LG P KEE+ +I EVD++ +G I Sbjct: 3 LSEEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTI 62 Query: 85 SFNDFLAVMTQKMA 98 F +FL +M ++M Sbjct: 63 DFEEFLVMMVRQMK 76 Score = 73.1 bits (178), Expect = 6e-14, Method: Composition-based stats. Identities = 29/69 (42%), Positives = 40/69 (57%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 ++ E AF +FD D G IS K L V LG++ T EEL +I+E D DG G ++ Sbjct: 5 EEMIAEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPTKEELDAIIEEVDEDGSGTIDF 64 Query: 160 EEFLKIMKK 168 EEFL +M + Sbjct: 65 EEFLVMMVR 73 Score = 30.3 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 23/64 (35%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E K D + G IS + VM KEE+ D+D +G I F+ Sbjct: 9 AEFKAAFDMFDADGGGDISTKELGTVMRMLGQNPT-KEELDAIIEEVDEDGSGTIDFEEF 67 Query: 127 KRVA 130 + Sbjct: 68 LVMM 71 >3E3R-A nrPDB Length = 204 Score = 79.2 bits (194), Expect = 9e-16, Method: Composition-based stats. Identities = 35/141 (24%), Positives = 61/141 (43%), Gaps = 9/141 (6%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 Q + F D DGS ++D E + + LG + E + + + D+ +G + +F Sbjct: 36 IQGLARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEF 95 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN-------ELGESLTDEEL 142 L + M++ + I AF D G ++ +L+ V + GE DE L Sbjct: 96 LRALRPPMSQA-REAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHPKVRSGEWTEDEVL 154 Query: 143 QEMIDEAD-RDGDGEVNEEEF 162 + +D D + DG+V EF Sbjct: 155 RRFLDNFDSSEKDGQVTLAEF 175 Score = 50.0 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 32/62 (51%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 + + FR D D + + ++ +LG L E + + + DR+G G ++ EEFL+ Sbjct: 39 LARFFRQLDRDGSRSLDADEFRQGLAKLGLVLDQAEAEGVCRKWDRNGSGTLDLEEFLRA 98 Query: 166 MK 167 ++ Sbjct: 99 LR 100 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 45/114 (39%), Gaps = 9/114 (7%) Query: 5 FRKSNVASTSYKRKVGP-KPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR----- 58 + ++ + + + +P +++ ++ + AF D G G + V +L+ Sbjct: 82 WDRNGSGTLDLEEFLRALRPPMSQAREAVIAAAFAKLDRSGDGVVTVDDLRGVYSGRAHP 141 Query: 59 --ALGFEPRKEEMKKMISEVD-KEATGKISFNDFLAVMTQKMAEKDTKEEILKA 109 G E +++ + D E G+++ +F + A +T EE + Sbjct: 142 KVRSGEWTEDEVLRRFLDNFDSSEKDGQVTLAEFQDYYSGVSASMNTDEEFVAM 195 >2R2I-A nrPDB Length = 198 Score = 78.8 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 35/132 (26%), Positives = 63/132 (47%), Gaps = 9/132 (6%) Query: 45 SGTIDVKELKVAMRALGFEPR-KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 SG + + E K P + +++M D G I F +++A ++ + + Sbjct: 29 SGQLTLYEFKQFFGLKNLSPSANKYVEQMFETFDFNKDGYIDFMEYVAALS-LVLKGKVD 87 Query: 104 EEILKAFRLFDDDETGKISFKNLK------RVANELGESLTDEELQEM-IDEADRDGDGE 156 +++ F+L+D D G I L R N E++T EE M D+ D +GDGE Sbjct: 88 QKLRWYFKLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGE 147 Query: 157 VNEEEFLKIMKK 168 ++ EEF++ ++K Sbjct: 148 LSLEEFMEGVQK 159 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 45/119 (37%), Gaps = 7/119 (5%) Query: 14 SYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMI 73 +K+ G K L+ + V + F+ FD + G ID E A+ + ++++ Sbjct: 36 EFKQFFGLK-NLSPSANKYVEQMFETFDFNKDGYIDFMEYVAALSLVLKGKVDQKLRWYF 94 Query: 74 SEVDKEATGKISFNDFLAV------MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 D + G I + L + + + +E F D + G++S + Sbjct: 95 KLYDVDGNGCIDRGELLNIIKAIRAINRCNEAMTAEEFTNMVFDKIDINGDGELSLEEF 153 Score = 26.8 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 9/59 (15%), Positives = 22/59 (37%), Gaps = 5/59 (8%) Query: 31 QEVRE-AFDLFDSDGSGTIDVKELKVAMRA----LGFEPRKEEMKKMISEVDKEATGKI 84 +E FD D +G G + ++E ++ L R ++ ++ + + Sbjct: 130 EEFTNMVFDKIDINGDGELSLEEFMEGVQKDEVLLDILTRSLDLTHIVKLIQNDGKNPH 188 >2B1U-A nrPDB Length = 71 Score = 78.8 bits (193), Expect = 1e-15, Method: Composition-based stats. Identities = 30/65 (46%), Positives = 39/65 (60%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E++ AFR FD D G I+ L+R LG+ L EEL MI EAD D DG VN EEF Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFA 65 Query: 164 KIMKK 168 +++ + Sbjct: 66 RMLAQ 70 Score = 69.6 bits (169), Expect = 7e-13, Method: Composition-based stats. Identities = 24/66 (36%), Positives = 40/66 (60%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 ++++ AF FD DG G I V EL+ AM LG +EE+ MI E D + G++++ +F Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLGQPLPQEELDAMIREADVDQDGRVNYEEFA 65 Query: 91 AVMTQK 96 ++ Q+ Sbjct: 66 RMLAQE 71 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E+++ D++ G I+ ++ M + + +EE+ R D D+ G+++++ Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAG-LGQPLPQEELDAMIREADVDQDGRVNYEEF 64 Query: 127 KRVA 130 R+ Sbjct: 65 ARML 68 Score = 27.2 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 15/31 (48%) Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 E+LQ D+DGDG + +E + M Sbjct: 6 EDLQVAFRAFDQDGDGHITVDELRRAMAGLG 36 >2HF5-A nrPDB Length = 68 Score = 77.7 bits (190), Expect = 2e-15, Method: Composition-based stats. Identities = 31/68 (45%), Positives = 44/68 (64%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E++ MI+EVD + G I F +FL +M +KM + D++EEI +AFR+FD D G IS L Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 127 KRVANELG 134 + V LG Sbjct: 61 RHVMTNLG 68 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 18/63 (28%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 1 MASTFRKSNVASTSYKRK--VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMR 58 M + + + + + D ++E+REAF +FD DG+G I EL+ M Sbjct: 6 MINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELRHVMT 65 Query: 59 ALG 61 LG Sbjct: 66 NLG 68 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 14/30 (46%), Positives = 21/30 (70%) Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 ELQ+MI+E D DG+G ++ EFL +M + Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKM 31 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 1/67 (1%) Query: 105 EILKAFRLFDDDETGKISFKNLKRVA-NELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E+ D D G I F + ++ ++ ++EE++E D+DG+G ++ E Sbjct: 2 ELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAELR 61 Query: 164 KIMKKTN 170 +M Sbjct: 62 HVMTNLG 68 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 34/65 (52%), Gaps = 1/65 (1%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAM-RALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 E+++ + D+DG+GTID E M R + +EE+++ DK+ G IS + Sbjct: 1 AELQDMINEVDADGNGTIDFPEFLTMMARKMKDTDSEEEIREAFRVFDKDGNGYISAAEL 60 Query: 90 LAVMT 94 VMT Sbjct: 61 RHVMT 65 >2K2I-A nrPDB Length = 79 Score = 77.7 bits (190), Expect = 2e-15, Method: Composition-based stats. Identities = 71/79 (89%), Positives = 78/79 (98%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 TQKM+EKDTKEEILKAF+LFDDDETGKISFKNLKRVA ELGE+LTDEELQEMIDEADRDG Sbjct: 1 TQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDG 60 Query: 154 DGEVNEEEFLKIMKKTNLY 172 DGEV+E+EFL+IMKKT+LY Sbjct: 61 DGEVSEQEFLRIMKKTSLY 79 Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 27/69 (39%), Positives = 43/69 (62%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D K+E+ +AF LFD D +G I K LK + LG EE+++MI E D++ G++S Sbjct: 7 KDTKEEILKAFKLFDDDETGKISFKNLKRVAKELGENLTDEELQEMIDEADRDGDGEVSE 66 Query: 87 NDFLAVMTQ 95 +FL +M + Sbjct: 67 QEFLRIMKK 75 Score = 31.9 bits (71), Expect = 0.15, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 34/67 (50%), Gaps = 1/67 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 KEE+ K D + TGKISF + L + +++ E T EE+ + D D G++S + Sbjct: 9 TKEEILKAFKLFDDDETGKISFKN-LKRVAKELGENLTDEELQEMIDEADRDGDGEVSEQ 67 Query: 125 NLKRVAN 131 R+ Sbjct: 68 EFLRIMK 74 >4GJF-A nrPDB Length = 89 Score = 76.5 bits (187), Expect = 5e-15, Method: Composition-based stats. Identities = 33/85 (38%), Positives = 49/85 (57%), Gaps = 1/85 (1%) Query: 18 KVGPKPELTEDQKQEVREAFDLFDSDG-SGTIDVKELKVAMRALGFEPRKEEMKKMISEV 76 +LTE+QK E + AFD+F G I KEL MR LG P EE+++MI EV Sbjct: 5 YKAAVEQLTEEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEV 64 Query: 77 DKEATGKISFNDFLAVMTQKMAEKD 101 D++ +G + F++FL +M + M + Sbjct: 65 DEDGSGTVDFDEFLVMMVRCMKDDS 89 Score = 73.8 bits (180), Expect = 4e-14, Method: Composition-based stats. Identities = 33/72 (45%), Positives = 43/72 (59%), Gaps = 1/72 (1%) Query: 100 KDTKEEILKAFRLF-DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 ++ K E AF +F E G IS K L +V LG++ T EELQEMIDE D DG G V+ Sbjct: 14 EEQKNEFKAAFDIFVQGAEDGCISTKELGKVMRMLGQNPTPEELQEMIDEVDEDGSGTVD 73 Query: 159 EEEFLKIMKKTN 170 +EFL +M + Sbjct: 74 FDEFLVMMVRCM 85 >2JOJ-A nrPDB Length = 77 Score = 76.2 bits (186), Expect = 6e-15, Method: Composition-based stats. Identities = 42/77 (54%), Positives = 63/77 (81%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E+QKQE++EAFDLFD++ +G+ID ELKVAMRALGF+ +K E+ ++++E D+E G I Sbjct: 1 LSEEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYI 60 Query: 85 SFNDFLAVMTQKMAEKD 101 F+DFL +MT+K+ +D Sbjct: 61 GFDDFLDIMTEKIKNRD 77 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 26/67 (38%), Positives = 43/67 (64%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 ++ K+EI +AF LFD ++TG I + LK LG + E+ E+++E DR+G+G + Sbjct: 3 EEQKQEIKEAFDLFDTNKTGSIDYHELKVAMRALGFDVKKPEILELMNEYDREGNGYIGF 62 Query: 160 EEFLKIM 166 ++FL IM Sbjct: 63 DDFLDIM 69 Score = 34.9 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 18/67 (26%), Positives = 31/67 (46%), Gaps = 1/67 (1%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 K+E+K+ D TG I +++ L V + + K EIL+ +D + G I F + Sbjct: 6 KQEIKEAFDLFDTNKTGSIDYHE-LKVAMRALGFDVKKPEILELMNEYDREGNGYIGFDD 64 Query: 126 LKRVANE 132 + E Sbjct: 65 FLDIMTE 71 >1OQP-A nrPDB Length = 77 Score = 75.0 bits (183), Expect = 1e-14, Method: Composition-based stats. Identities = 50/74 (67%), Positives = 67/74 (90%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 E+D++EEILKAFRLFDDD +G I+ K+L+RVA ELGE+LT+EELQEMI EADR+ D E++ Sbjct: 4 ERDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEID 63 Query: 159 EEEFLKIMKKTNLY 172 E+EF++IMKKT+L+ Sbjct: 64 EDEFIRIMKKTSLF 77 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 25/69 (36%), Positives = 45/69 (65%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 D ++E+ +AF LFD D SGTI +K+L+ + LG +EE+++MI+E D+ +I Sbjct: 5 RDSREEILKAFRLFDDDNSGTITIKDLRRVAKELGENLTEEELQEMIAEADRNDDNEIDE 64 Query: 87 NDFLAVMTQ 95 ++F+ +M + Sbjct: 65 DEFIRIMKK 73 Score = 30.3 bits (67), Expect = 0.45, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 32/71 (45%), Gaps = 1/71 (1%) Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 G +EE+ K D + +G I+ D L + +++ E T+EE+ + D ++ + Sbjct: 3 GERDSREEILKAFRLFDDDNSGTITIKD-LRRVAKELGENLTEEELQEMIAEADRNDDNE 61 Query: 121 ISFKNLKRVAN 131 I R+ Sbjct: 62 IDEDEFIRIMK 72 >1JUO-A nrPDB Length = 198 Score = 74.6 bits (182), Expect = 2e-14, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 56/130 (43%), Gaps = 14/130 (10%) Query: 45 SGTIDVKELKVAMRALG----FEPRKEEMKK-MISEVDKEATGKISFNDFLAVMTQKMAE 99 G ID EL+ + G ++P E + M+S +D++ +G + FN+F + Sbjct: 46 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 105 Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + F FD D +G + + L++ +G L+ + + + + G++ Sbjct: 106 RQH-------FISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTN--GKITF 156 Query: 160 EEFLKIMKKT 169 ++++ K Sbjct: 157 DDYIACCVKL 166 Score = 68.8 bits (167), Expect = 1e-12, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 14/125 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M S + + + L R+ F FD+D SGT+D +EL+ A+ + Sbjct: 78 MVSMLDRDMSGTMGFNEFKELWAVLNGW-----RQHFISFDTDRSGTVDPQELQKALTTM 132 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF + + + GKI+F+D++A + + +FR D + G Sbjct: 133 GFRLSPQAVNSIAKRYST--NGKITFDDYIACCVKLR-------ALTDSFRRRDTAQQGV 183 Query: 121 ISFKN 125 ++F Sbjct: 184 VNFPY 188 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 5/54 (9%) Query: 117 ETGKISFKNLKRVANELG-----ESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 + G+I L+R + G + E + M+ DRD G + EF ++ Sbjct: 45 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKEL 98 >2NA0-A nrPDB Length = 205 Score = 74.2 bits (181), Expect = 3e-14, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 10/133 (7%) Query: 45 SGTIDVKELKVAMRALGFEP-RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 SG + + E + P + +++M D G I F ++ A ++ + + + Sbjct: 31 SGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNKDGYIDFMEYEAALS-LVLKGKVE 89 Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANEL-------GESLTDEEL-QEMIDEADRDGDG 155 +++ F+L+D D G I L + + ++T EE + + D +GDG Sbjct: 90 QKLRWYFKLYDVDGNGCIDRDELLTIIRAIRAINPCSDSTMTAEEFTDTVFSKIDVNGDG 149 Query: 156 EVNEEEFLKIMKK 168 E++ EEF++ ++K Sbjct: 150 ELSLEEFMEGVQK 162 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 46/106 (43%), Gaps = 1/106 (0%) Query: 63 EPRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 E E + + E +G+++ +F K + + + F FD ++ G I Sbjct: 12 ELSSTECHQWYKKFMTECPSGQLTLYEFRQFFGLKNLSPWASQYVEQMFETFDFNKDGYI 71 Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 F + + + + +++L+ D DG+G ++ +E L I++ Sbjct: 72 DFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIR 117 Score = 42.3 bits (98), Expect = 1e-04, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 9/128 (7%) Query: 1 MASTFRKSNVASTSYKRKVGPKP-ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 M TF + + L +Q++R F L+D DG+G ID EL +RA Sbjct: 59 MFETFDFNKDGYIDFMEYEAALSLVLKGKVEQKLRWYFKLYDVDGNGCIDRDELLTIIRA 118 Query: 60 L-------GFEPRKEEM-KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFR 111 + EE + S++D G++S +F+ + + DT L R Sbjct: 119 IRAINPCSDSTMTAEEFTDTVFSKIDVNGDGELSLEEFMEGVQKDQMLLDTLTRSLDLTR 178 Query: 112 LFDDDETG 119 + + G Sbjct: 179 IVRRLQNG 186 >2K7B-A nrPDB Length = 76 Score = 73.5 bits (179), Expect = 4e-14, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 42/70 (60%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L ++ +E+REAF FD D G I+ ++L MR +G+ P + E+ ++ +++ G + Sbjct: 4 LRPEEIEELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHV 63 Query: 85 SFNDFLAVMT 94 F+DF+ +M Sbjct: 64 DFDDFVELMG 73 Score = 55.7 bits (133), Expect = 8e-09, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 38/63 (60%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 EE+ +AFR FD D+ G I+ ++L +G T+ EL E+ + + + G V+ ++F+ Sbjct: 10 EELREAFREFDKDKDGYINCRDLGNCMRTMGYMPTEMELIELSQQINMNLGGHVDFDDFV 69 Query: 164 KIM 166 ++M Sbjct: 70 ELM 72 >5MRA-A nrPDB Length = 167 Score = 73.1 bits (178), Expect = 5e-14, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 56/130 (43%), Gaps = 14/130 (10%) Query: 45 SGTIDVKELKVAMRALG----FEPRKEEMKK-MISEVDKEATGKISFNDFLAVMTQKMAE 99 G ID EL+ + G ++P E + M+S +D++ +G + FN+F + Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + F FD D +G + + L++ +G L+ + + + + G++ Sbjct: 75 RQH-------FISFDTDRSGTVDPQELQKALTTMGFRLSPQAVNSIAKRYSTN--GKITF 125 Query: 160 EEFLKIMKKT 169 ++++ K Sbjct: 126 DDYIACCVKL 135 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 28/125 (22%), Positives = 51/125 (40%), Gaps = 14/125 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M S + + + L R+ F FD+D SGT+D +EL+ A+ + Sbjct: 47 MVSMLDRDMSGTMGFNEFKELWAVLNGW-----RQHFISFDTDRSGTVDPQELQKALTTM 101 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF + + + GKI+F+D++A + + +FR D + G Sbjct: 102 GFRLSPQAVNSIAKRYST--NGKITFDDYIACCVKLR-------ALTDSFRRRDTAQQGV 152 Query: 121 ISFKN 125 ++F Sbjct: 153 VNFPY 157 Score = 38.0 bits (87), Expect = 0.002, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 5/54 (9%) Query: 117 ETGKISFKNLKRVANELG-----ESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 + G+I L+R + G + E + M+ DRD G + EF ++ Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKEL 67 >1JF0-A nrPDB Length = 195 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 8 SNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE 67 N+A+ + +P L + FD+FD DGSGTI + E K R G P +E Sbjct: 93 KNLANADLAKWARNEPTLIREWGD---AVFDIFDKDGSGTITLDEWKAYGRISGISPSEE 149 Query: 68 EMKKMISEVDKEATGKISFNDF 89 + +K D + +G++ ++ Sbjct: 150 DCEKTFQHCDLDNSGELDVDEM 171 Score = 71.9 bits (175), Expect = 1e-13, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 58/158 (36%), Gaps = 20/158 (12%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELK-----VAMRALGFEPRKEE-----MKKMISEV 76 + + FD D +G+G I + E+ + LG P + + ++ Sbjct: 16 PKWIKRHKFMFDYLDINGNGQITLDEIVSKASDDICKNLGATPAQTQRHQDCVEAFFRGC 75 Query: 77 DKEATGKISFNDFLAV---MTQKMAEKDTKEEIL-------KAFRLFDDDETGKISFKNL 126 E + F +FL + K + E F +FD D +G I+ Sbjct: 76 GLEYGKETKFPEFLEGWKNLANADLAKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEW 135 Query: 127 KRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 K G S ++E+ ++ D D GE++ +E + Sbjct: 136 KAYGRISGISPSEEDCEKTFQHCDLDNSGELDVDEMTR 173 >2M8U-A nrPDB Length = 77 Score = 71.1 bits (173), Expect = 2e-13, Method: Composition-based stats. Identities = 26/71 (36%), Positives = 45/71 (63%) Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDG 155 M +TK ++++AF++FD D G ++ L++V NELG+ + +E++EMI EAD G Sbjct: 3 HMNHINTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSG 62 Query: 156 EVNEEEFLKIM 166 V E F+ ++ Sbjct: 63 YVQYETFVGML 73 Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 21/66 (31%), Positives = 39/66 (59%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 + K +V EAF +FD DG+G + V L+ + LG +E+++MI E D + +G + + Sbjct: 8 NTKAQVIEAFKVFDRDGNGYVTVDYLRKVLNELGDMMPADEIEEMIYEADPQNSGYVQYE 67 Query: 88 DFLAVM 93 F+ ++ Sbjct: 68 TFVGML 73 >3H4S-E nrPDB Length = 135 Score = 70.8 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 34/106 (32%), Positives = 56/106 (52%), Gaps = 1/106 (0%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 + K M+ E + + D L VM +KM ++ E+ K F L D E I+ ++ Sbjct: 2 EPTEKSMLLETTSTTKMETKYEDMLPVMAEKMDVEEFVSELCKGFSLLADPERHLITAES 61 Query: 126 LKRVANELG-ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 L+R + LG E ++ E+ Q M+ E D DGDG +N+ EF +M + + Sbjct: 62 LRRNSGILGIEGMSKEDAQGMVREGDLDGDGALNQTEFCVLMVRLS 107 Score = 32.6 bits (73), Expect = 0.080, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 33/80 (41%), Gaps = 1/80 (1%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE-PRKEEMKKMISEVDKEATGKIS 85 E+ E+ + F L I + L+ LG E KE+ + M+ E D + G ++ Sbjct: 36 EEFVSELCKGFSLLADPERHLITAESLRRNSGILGIEGMSKEDAQGMVREGDLDGDGALN 95 Query: 86 FNDFLAVMTQKMAEKDTKEE 105 +F +M + E E Sbjct: 96 QTEFCVLMVRLSPEMMEDAE 115 >1GJY-A nrPDB Length = 167 Score = 70.8 bits (172), Expect = 3e-13, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 54/130 (41%), Gaps = 14/130 (10%) Query: 45 SGTIDVKELKVAMRALG----FEPRKEEMKK-MISEVDKEATGKISFNDFLAVMTQKMAE 99 G ID EL+ + G ++P E + M+S +D++ +G + FN+F + Sbjct: 15 DGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKELWAVLNGW 74 Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + F FD D +G + + L++ +G L + + + G++ Sbjct: 75 RQH-------FISFDSDRSGTVDPQELQKALTTMGFRLNPQTVNSIAKRYST--SGKITF 125 Query: 160 EEFLKIMKKT 169 ++++ K Sbjct: 126 DDYIACCVKL 135 Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 29/125 (23%), Positives = 52/125 (41%), Gaps = 14/125 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M S + + + L R+ F FDSD SGT+D +EL+ A+ + Sbjct: 47 MVSMLDRDMSGTMGFNEFKELWAVLNGW-----RQHFISFDSDRSGTVDPQELQKALTTM 101 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF + + + +GKI+F+D++A + + +FR D + G Sbjct: 102 GFRLNPQTVNSIAKRYST--SGKITFDDYIACCVKLR-------ALTDSFRRRDSAQQGM 152 Query: 121 ISFKN 125 ++F Sbjct: 153 VNFSY 157 Score = 37.2 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 5/54 (9%) Query: 117 ETGKISFKNLKRVANELG-----ESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 + G+I L+R + G + E + M+ DRD G + EF ++ Sbjct: 14 QDGQIDADELQRCLTQSGIAGGYKPFNLETCRLMVSMLDRDMSGTMGFNEFKEL 67 >5T7C-A nrPDB Length = 193 Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 63/155 (40%), Gaps = 19/155 (12%) Query: 26 TEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRAL---GFEPRKEEMKKMISEVDKEAT 81 TE E++E + F D +G + V E K G + E + D Sbjct: 20 TEFTDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAE--HVFRTFDTNGD 77 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR-----------VA 130 G I F +F+ ++ + ++++ AF ++D D G IS + V Sbjct: 78 GTIDFREFIIALS-VTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQAIYKMVSSVM 136 Query: 131 NELGESLTDEE-LQEMIDEADRDGDGEVNEEEFLK 164 + T E+ ++ + D + DG+++ EEF++ Sbjct: 137 KMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIR 171 Score = 69.2 bits (168), Expect = 8e-13, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 48/116 (41%), Gaps = 11/116 (9%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + F FD++G GTID +E +A+ ++++K S D + G IS + Sbjct: 60 DASKFAEHVFRTFDTNGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRS 119 Query: 88 DFLAV-----------MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + L + M E ++ K FR D + GK+S + R A Sbjct: 120 EMLEIVQAIYKMVSSVMKMPEDESTPEKRTDKIFRQMDTNNDGKLSLEEFIRGAKS 175 Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 44/104 (42%), Gaps = 1/104 (0%) Query: 65 RKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 E+++ K+ TG ++ ++F + D + FR FD + G I F Sbjct: 23 TDHELQEWYKGFLKDCPTGHLTVDEFKKIYANFFPYGDASKFAEHVFRTFDTNGDGTIDF 82 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + + +++L+ D DG+G ++ E L+I++ Sbjct: 83 REFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISRSEMLEIVQ 126 >2GGZ-A nrPDB Length = 211 Score = 70.0 bits (170), Expect = 5e-13, Method: Composition-based stats. Identities = 32/131 (24%), Positives = 61/131 (46%), Gaps = 8/131 (6%) Query: 45 SGTIDVKELKVAMRALGFEPR-KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 SG + E K + G + + + ++ + D G + F +F+A + M EK + Sbjct: 34 SGLQTLHEFKTLLGLQGLNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEK-ME 92 Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELG-----ESLTDEE-LQEMIDEADRDGDGEV 157 +++ F+L+D D G I L + + ++L+ EE + + + D + DGE+ Sbjct: 93 QKLKWYFKLYDADGNGSIDKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGEL 152 Query: 158 NEEEFLKIMKK 168 EEF+ M K Sbjct: 153 TLEEFINGMAK 163 Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 43/111 (38%), Gaps = 5/111 (4%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L + + + + ++ FD++ G +D E A+ + E ++++K D + G I Sbjct: 51 LNQKANKHIDQVYNTFDTNKDGFVDFLEFIAAVNLIMQEKMEQKLKWYFKLYDADGNGSI 110 Query: 85 SFNDFLAVMTQK-----MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 N+ L + +E I F D + G+++ + Sbjct: 111 DKNELLDMFMAVQALNGQQTLSPEEFINLVFHKIDINNDGELTLEEFINGM 161 >1BJF-A nrPDB Length = 193 Score = 70.0 bits (170), Expect = 6e-13, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 68/164 (41%), Gaps = 19/164 (11%) Query: 17 RKVGPKPELTEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRAL---GFEPRKEEMKKM 72 + E T+ + E++E + F D SG + ++E K G + E + Sbjct: 11 EVMQDLLESTDFTEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDASKFAE--HV 68 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR---- 128 D G I F +F+ ++ + ++++ AF ++D D G IS + Sbjct: 69 FRTFDANGDGTIDFREFIIALS-VTSRGKLEQKLKWAFSMYDLDGNGYISKAEMLEIVQA 127 Query: 129 -------VANELGESLTDEE-LQEMIDEADRDGDGEVNEEEFLK 164 V + T E+ +++ + D + DG+++ EEF++ Sbjct: 128 IYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIR 171 Score = 66.9 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 29/116 (25%), Positives = 47/116 (40%), Gaps = 11/116 (9%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + F FD++G GTID +E +A+ ++++K S D + G IS Sbjct: 60 DASKFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKA 119 Query: 88 DFLAV-----------MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + L + M E ++ K FR D + GK+S + R A Sbjct: 120 EMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNRDGKLSLEEFIRGAKS 175 Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 21/124 (16%), Positives = 53/124 (42%), Gaps = 3/124 (2%) Query: 45 SGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTK 103 + + + ++ + + F + E+++ ++ +G +S +F + D Sbjct: 5 NSKLRPEVMQDLLESTDF--TEHEIQEWYKGFLRDCPSGHLSMEEFKKIYGNFFPYGDAS 62 Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 + FR FD + G I F+ + +++L+ D DG+G +++ E L Sbjct: 63 KFAEHVFRTFDANGDGTIDFREFIIALSVTSRGKLEQKLKWAFSMYDLDGNGYISKAEML 122 Query: 164 KIMK 167 +I++ Sbjct: 123 EIVQ 126 >1F4Q-A nrPDB Length = 165 Score = 69.6 bits (169), Expect = 6e-13, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 53/130 (40%), Gaps = 14/130 (10%) Query: 45 SGTIDVKELKVAMRALGFEPR-----KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 G +D +EL+ + G E + MI+ +D++ TGK+ FN F + Sbjct: 13 DGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKELWA----- 67 Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + F D D +G + L++ +G L+ + L ++ ++ G + Sbjct: 68 --ALNAWKENFMTVDQDGSGTVEHHELRQAIGLMGYRLSPQTLTTIVKRYSKN--GRIFF 123 Query: 160 EEFLKIMKKT 169 ++++ K Sbjct: 124 DDYVACCVKL 133 Score = 57.7 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 47/119 (39%), Gaps = 14/119 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + + + + L +E F D DGSGT++ EL+ A+ + Sbjct: 45 MIAMLDRDHTGKMGFNAFKELWAALNAW-----KENFMTVDQDGSGTVEHHELRQAIGLM 99 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETG 119 G+ + + ++ K G+I F+D++A + A D F+ D + G Sbjct: 100 GYRLSPQTLTTIVKRYSK--NGRIFFDDYVACCVKLRALTDF-------FKKRDHLQQG 149 Score = 33.8 bits (76), Expect = 0.039, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 24/54 (44%), Gaps = 5/54 (9%) Query: 117 ETGKISFKNLKRVANELG-----ESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 + G++ + L+R + G + E + MI DRD G++ F ++ Sbjct: 12 QDGEVDAEELQRCLTQSGINGTYSPFSLETCRIMIAMLDRDHTGKMGFNAFKEL 65 >1S36-A nrPDB Length = 195 Score = 69.2 bits (168), Expect = 8e-13, Method: Composition-based stats. Identities = 31/156 (19%), Positives = 55/156 (35%), Gaps = 20/156 (12%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELK-----VAMRALGFEPRKEE-----MKKMISEVDK 78 + + FD D +G+G I + E+ L P + + ++ Sbjct: 18 WIKRHKHMFDFLDINGNGKITLDEIVSKASDDICAKLEATPEQTKRHQVCVEAFFRGCGM 77 Query: 79 EATGKISFNDFLAVMTQKMAEKDTK----------EEILKAFRLFDDDETGKISFKNLKR 128 E +I+F FL Q + K E F +FD D +G I+ K Sbjct: 78 EYGKEIAFPQFLDGFKQLATSELKKWARNEPTLIREWGDAVFDIFDKDGSGTITLDEWKA 137 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 G S + E+ + D D G+++ +E + Sbjct: 138 YGKISGISPSQEDCEATFRHCDLDNSGDLDVDEMTR 173 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 8 SNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE 67 +A++ K+ +P L + FD+FD DGSGTI + E K + G P +E Sbjct: 93 KQLATSELKKWARNEPTLIREWGD---AVFDIFDKDGSGTITLDEWKAYGKISGISPSQE 149 Query: 68 EMKKMISEVDKEATGKISFNDF 89 + + D + +G + ++ Sbjct: 150 DCEATFRHCDLDNSGDLDVDEM 171 >2JNX-A nrPDB Length = 134 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 62/133 (46%), Gaps = 6/133 (4%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 F D++G G++ +E+K + + ++ ++ + +D + G+I +F Sbjct: 3 EALFKQLDANGDGSVSYEEVKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKFA 62 Query: 94 TQKMAEKDTKEE--ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + + E+ + ++L D D GK++ + + + G E++ + I +AD Sbjct: 63 AAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY----EKVVDQIMKADA 118 Query: 152 DGDGEVNEEEFLK 164 +GDG + EEFL Sbjct: 119 NGDGYITLEEFLA 131 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 44/102 (43%), Gaps = 4/102 (3%) Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL-KR 128 + + ++D G +S+ + + ++ + F+ D D G+I K Sbjct: 3 EALFKQLDANGDGSVSYEE-VKAFVSSKRPIKNEQLLQLIFKAIDIDGNGEIDLAEFTKF 61 Query: 129 VANELGESLTDEE--LQEMIDEADRDGDGEVNEEEFLKIMKK 168 A + L+DE+ L+ + D DGDG++ +EE KK Sbjct: 62 AAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKK 103 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 50/114 (43%), Gaps = 10/114 (8%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE---MKKM 72 K V K + +Q ++ F D DG+G ID+ E A+ + +E +K + Sbjct: 23 KAFVSSKRPIKNEQLLQL--IFKAIDIDGNGEIDLAEFTKFAAAVKEQDLSDEKVGLKIL 80 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 +D + GK++ + + +K + ++I+KA D + G I+ + Sbjct: 81 YKLMDADGDGKLTKEE-VTTFFKKFGYEKVVDQIMKA----DANGDGYITLEEF 129 Score = 42.6 bits (99), Expect = 8e-05, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 35/77 (45%), Gaps = 4/77 (5%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE 75 K K + D+K ++ + L D+DG G + +E+ + G+ E++ I + Sbjct: 60 KFAAAVKEQDLSDEKVGLKILYKLMDADGDGKLTKEEVTTFFKKFGY----EKVVDQIMK 115 Query: 76 VDKEATGKISFNDFLAV 92 D G I+ +FLA Sbjct: 116 ADANGDGYITLEEFLAF 132 >2K7C-A nrPDB Length = 72 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 42/71 (59%), Gaps = 1/71 (1%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-GESLTDEELQEMIDEADRDGDGEV 157 + +E+ AFR FD + G+IS L+ +L G + +++E+I + D +GDG V Sbjct: 2 DMIGVKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRV 61 Query: 158 NEEEFLKIMKK 168 + EEF+++M + Sbjct: 62 DFEEFVRMMSR 72 Score = 65.0 bits (157), Expect = 1e-11, Method: Composition-based stats. Identities = 23/67 (34%), Positives = 43/67 (64%), Gaps = 1/67 (1%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRA-LGFEPRKEEMKKMISEVDKEATGKISFND 88 +E+R+AF FD++G G I EL+ AMR LG + +++++I +VD G++ F + Sbjct: 6 VKELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEE 65 Query: 89 FLAVMTQ 95 F+ +M++ Sbjct: 66 FVRMMSR 72 Score = 36.5 bits (83), Expect = 0.005, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 29/64 (45%) Query: 68 EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLK 127 E++ E D G+IS ++ M + + + +I + R D + G++ F+ Sbjct: 8 ELRDAFREFDTNGDGEISTSELREAMRKLLGHQVGHRDIEEIIRDVDLNGDGRVDFEEFV 67 Query: 128 RVAN 131 R+ + Sbjct: 68 RMMS 71 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 20/33 (60%) Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 +EL++ E D +GDGE++ E + M+K + Sbjct: 7 KELRDAFREFDTNGDGEISTSELREAMRKLLGH 39 >5I2L-A nrPDB Length = 120 Score = 68.4 bits (166), Expect = 1e-12, Method: Composition-based stats. Identities = 28/100 (28%), Positives = 49/100 (49%), Gaps = 3/100 (3%) Query: 8 SNVASTSYKRKVGPKPEL---TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEP 64 S + +R P E + Q +++ + F +D+ G ID+ ELK+ M LG Sbjct: 5 SGEPQSPSRRVFNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQ 64 Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKE 104 +K MI EVD++ K+SF +FL + + A + ++ Sbjct: 65 THLGLKNMIKEVDEDFDSKLSFREFLLIFRKAAAGELQED 104 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 24/80 (30%), Positives = 37/80 (46%) Query: 89 FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDE 148 F K + +++ K F+ +D G I LK + +LG T L+ MI E Sbjct: 16 FNPYTEFKEFSRKQIKDMEKMFKQYDAGRDGFIDLMELKLMMEKLGAPQTHLGLKNMIKE 75 Query: 149 ADRDGDGEVNEEEFLKIMKK 168 D D D +++ EFL I +K Sbjct: 76 VDEDFDSKLSFREFLLIFRK 95 Score = 27.2 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 17/31 (54%) Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +++++M + D DG ++ E +M+K Sbjct: 31 KDMEKMFKQYDAGRDGFIDLMELKLMMEKLG 61 >3KPX-A nrPDB Length = 198 Score = 68.4 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 59/158 (37%), Gaps = 20/158 (12%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELK-----VAMRALGFEPRK-----EEMKKMISEV 76 + F+ D +G+G I + E+ LG P + E ++ ++ Sbjct: 19 PKWVNRHKFMFNFLDINGNGKITLDEIVSKASDDICAKLGATPAQTQRHQEAVEAFFKKI 78 Query: 77 DKEATGKISFNDFLAV---MTQKMAEKDTKEEI-------LKAFRLFDDDETGKISFKNL 126 + ++ F F+ + + + ++ + F +FD D +G IS Sbjct: 79 GLDYGKEVEFPAFVNGWKELAKHDLKLWSQNKKSLIRNWGEAVFDIFDKDGSGSISLDEW 138 Query: 127 KRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 K G +DE+ ++ D D G+++ +E + Sbjct: 139 KTYGGISGICPSDEDAEKTFKHCDLDNSGKLDVDEMTR 176 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 8 SNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE 67 +A K K L + + FD+FD DGSG+I + E K G P E Sbjct: 96 KELAKHDLKLWSQNKKSLIRNWGE---AVFDIFDKDGSGSISLDEWKTYGGISGICPSDE 152 Query: 68 EMKKMISEVDKEATGKISFNDF 89 + +K D + +GK+ ++ Sbjct: 153 DAEKTFKHCDLDNSGKLDVDEM 174 >2AUC-A nrPDB Length = 126 Score = 68.1 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 64/128 (50%), Gaps = 7/128 (5%) Query: 38 DLFDSDGS-GTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQK 96 D+F++ S G + +++ R LG P + KK+ +++ +L +T Sbjct: 2 DMFNTKSSNGKLRIEDASHNARKLGLAPSSTDEKKIRDLY----GDSLTYEQYLEYLTMC 57 Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 + ++D EE++K F FD++ +G ++ +K + G++LT++E + ++ + Sbjct: 58 VHDRDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSED--R 115 Query: 157 VNEEEFLK 164 +N + F + Sbjct: 116 INYKLFCE 123 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 29/63 (46%), Gaps = 2/63 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 D +E+ + F FD++ SG + ++K + G ++E ++ E +I++ Sbjct: 61 RDNMEELIKMFSHFDNNSSGFLTKNQMKNILTTWGDALTEQEANDALNAFSSED--RINY 118 Query: 87 NDF 89 F Sbjct: 119 KLF 121 >2I94-A nrPDB Length = 202 Score = 68.1 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 30/124 (24%), Positives = 56/124 (45%), Gaps = 3/124 (2%) Query: 44 GSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDT 102 SG + + L+ L + +EE+ KE +G+I+ +F + ++ E D Sbjct: 5 KSGALSKEILEEL--QLNTKFTEEELSSWYQSFLKECPSGRITRQEFQTIYSKFFPEADP 62 Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K FR FD + G + FK + T+++L+ D DG+G +++ E Sbjct: 63 KAYAQHVFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEV 122 Query: 163 LKIM 166 L+I+ Sbjct: 123 LEIV 126 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 41/104 (39%), Gaps = 13/104 (12%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 F FD++ GT+D KE +A+ ++++ S D + G IS N+ L ++T Sbjct: 69 VFRSFDANSDGTLDFKEYVIALHMTSAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVTA 128 Query: 96 -------------KMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E ++ K + F + K++ K Sbjct: 129 IFKMISPEDTKHLPEDENTPEKRAEKIWGFFGKKDDDKLTEKEF 172 >2G9B-A nrPDB Length = 263 Score = 68.1 bits (165), Expect = 2e-12, Method: Composition-based stats. Identities = 39/157 (24%), Positives = 71/157 (45%), Gaps = 22/157 (14%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE------EMKKMISEVDKEATGKIS 85 + E + FD+DGSG ++ KEL+ ++ L +K EMK + + + GKI Sbjct: 17 QFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSPEMKTFVDQYGQRDDGKIG 76 Query: 86 FNDFLAVMTQ--------KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES- 136 + V+ + + + EE +K +R +D D +G I + LK +L E Sbjct: 77 IVELAHVLPTEENFLLLFRCQQLKSCEEFMKTWRKYDTDHSGFIETEELKNFLKDLLEKA 136 Query: 137 ---LTDEELQE----MIDEADRDGDGEVNEEEFLKIM 166 + D +L E M+ D + DG++ E +++ Sbjct: 137 NKTVDDTKLAEYTDLMLKLFDSNNDGKLELTEMARLL 173 Score = 57.7 bits (138), Expect = 3e-09, Method: Composition-based stats. Identities = 30/129 (23%), Positives = 52/129 (40%), Gaps = 18/129 (13%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKK---------MISEVDKEAT 81 +E + + +D+D SG I+ +ELK ++ L E + + M+ D Sbjct: 103 EEFMKTWRKYDTDHSGFIETEELKNFLKDL-LEKANKTVDDTKLAEYTDLMLKLFDSNND 161 Query: 82 GKISFNDFLAVM-------TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG 134 GK+ + ++ + K +E KAF L+D D G I L + +L Sbjct: 162 GKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENELDALLKDLC 221 Query: 135 ESLTDEELQ 143 E +EL Sbjct: 222 EK-NKQELD 229 Score = 34.5 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 31/77 (40%), Gaps = 8/77 (10%) Query: 38 DLFDSDGSGTIDVKELKVAMRAL--------GFEPRKEEMKKMISEVDKEATGKISFNDF 89 LFDS+ G +++ E+ + G + +E K D++ G I N+ Sbjct: 154 KLFDSNNDGKLELTEMARLLPVQENFLLKFQGIKMCGKEFNKAFELYDQDGNGYIDENEL 213 Query: 90 LAVMTQKMAEKDTKEEI 106 A++ + + +I Sbjct: 214 DALLKDLCEKNKQELDI 230 Score = 33.0 bits (74), Expect = 0.069, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 35/80 (43%), Gaps = 8/80 (10%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL-------GESLTDEELQEMI 146 + + T + + + FD D +G + K L+ + EL G L+ E++ + Sbjct: 6 SHLQSSLITASQFFEIWLHFDADGSGYLEGKELQNLIQELLQARKKAGLELSP-EMKTFV 64 Query: 147 DEADRDGDGEVNEEEFLKIM 166 D+ + DG++ E ++ Sbjct: 65 DQYGQRDDGKIGIVELAHVL 84 >1JBA-A nrPDB Length = 204 Score = 67.7 bits (164), Expect = 2e-12, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 64/152 (42%), Gaps = 19/152 (12%) Query: 31 QEVREAFDLFDSD-GSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 +++E + F + SGT+ + E K + E + ++ M D I F ++ Sbjct: 22 AQLQEWYKKFLEECPSGTLFMHEFKRFFKVPDNEEATQYVEAMFRAFDTNGDNTIDFLEY 81 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---------------- 133 +A + + + ++ F+++D D G I + L + + Sbjct: 82 VAALN-LVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESIYKLKKACSVEVEAEQQ 140 Query: 134 GESLTDEE-LQEMIDEADRDGDGEVNEEEFLK 164 G+ LT EE + + D +GDG+++ EF++ Sbjct: 141 GKLLTPEEVVDRIFLLVDENGDGQLSLNEFVE 172 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 43/104 (41%), Gaps = 2/104 (1%) Query: 67 EEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 ++++ + +E +G + ++F E+ + + FR FD + I F Sbjct: 22 AQLQEWYKKFLEECPSGTLFMHEFKRFFKVPDNEE-ATQYVEAMFRAFDTNGDNTIDFLE 80 Query: 126 LKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 N + + +L+ D+D +G ++ +E L I++ Sbjct: 81 YVAALNLVLRGTLEHKLKWTFKIYDKDRNGCIDRQELLDIVESI 124 >4AOM-A nrPDB Length = 146 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 57/119 (47%), Gaps = 6/119 (5%) Query: 46 GTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEE 105 G I + R LG P + KK+ +++ +L ++ + +KD EE Sbjct: 30 GKISIDNASYNARKLGLAPSSIDEKKIKELYGDN----LTYEQYLEYLSICVHDKDNVEE 85 Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 ++K F FD++ TG ++ +K + G++LTD+E + ++ + + ++ + F + Sbjct: 86 LIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDN--IDYKLFCE 142 Score = 37.2 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D +E+ + F FD++ +G + ++K + G +E ++ E I + Sbjct: 80 KDNVEELIKMFAHFDNNCTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDN--IDY 137 Query: 87 NDF 89 F Sbjct: 138 KLF 140 >1KFX-S nrPDB Length = 184 Score = 67.3 bits (163), Expect = 3e-12, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 49/121 (40%), Gaps = 13/121 (10%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + ++ + Q + FD+D SGTI EL A A Sbjct: 63 MVAVMDSDTTGKLGFEEFKYLWNNIKRWQ-----AIYKQFDTDRSGTICSSELPGAFEAA 117 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF E + MI + +G + F++F++ + + + + +AF+ D D TG+ Sbjct: 118 GFHL-NEHLYNMIIRRYSDESGNMDFDNFISCLVRL-------DAMFRAFKSLDKDGTGQ 169 Query: 121 I 121 I Sbjct: 170 I 170 Score = 49.6 bits (117), Expect = 6e-07, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 55/151 (36%), Gaps = 17/151 (11%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAM-RALGFEPRK-------EEMKKMISEVDKE 79 ++ ++ R F D + EL + + + P + + M++ +D + Sbjct: 12 EEVRQFRRLFAQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 70 Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TGK+ F +F + + ++ FD D +G I L G L + Sbjct: 71 TTGKLGFEEF-------KYLWNNIKRWQAIYKQFDTDRSGTICSSELPGAFEAAGFHLNE 123 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +I D G ++ + F+ + + + Sbjct: 124 HLYNMIIRRY-SDESGNMDFDNFISCLVRLD 153 >1JC2-A nrPDB Length = 76 Score = 66.9 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 47/76 (61%) Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGD 154 + A+ ++EE+ FR+FD + G I + L + GE + +E++++++ ++D++ D Sbjct: 1 MEDAKGKSEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNND 60 Query: 155 GEVNEEEFLKIMKKTN 170 G ++ +EFLK+M+ Sbjct: 61 GRIDFDEFLKMMEGVQ 76 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 40/65 (61%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++E+ F +FD + G ID++EL +RA G +E+++ ++ + DK G+I F++ Sbjct: 8 SEEELANCFRIFDKNADGFIDIEELGEILRATGEHVIEEDIEDLMKDSDKNNDGRIDFDE 67 Query: 89 FLAVM 93 FL +M Sbjct: 68 FLKMM 72 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 27/67 (40%), Gaps = 1/67 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+ DK A G I + ++ + E +E+I + D + G+I F Sbjct: 8 SEEELANCFRIFDKNADGFIDIEELGEIL-RATGEHVIEEDIEDLMKDSDKNNDGRIDFD 66 Query: 125 NLKRVAN 131 ++ Sbjct: 67 EFLKMME 73 >5OTJ-D nrPDB Length = 110 Score = 66.9 bits (162), Expect = 4e-12, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 35/65 (53%), Gaps = 1/65 (1%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 +++ + F+ FD + GKIS L LG + + +E+Q M+ E D DGDG ++ E Sbjct: 1 MADDMERIFKRFDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNE 59 Query: 162 FLKIM 166 F+ Sbjct: 60 FISFC 64 Score = 62.3 bits (150), Expect = 9e-11, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 41/79 (51%), Gaps = 1/79 (1%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 ++ F FD++G G I + EL A+R LG +E+++M++E+D + G I FN+F+ Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNEFI 61 Query: 91 AVMTQKMAEKDTKEEILKA 109 + ++ K Sbjct: 62 SFCNANPGLMKDVAKVFKG 80 Score = 34.9 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 ++M+++ D GKIS ++ + + + +E+ + D D G I F Sbjct: 3 DDMERIFKRFDTNGDGKISLSELTDAL--RTLGSTSADEVQRMMAEIDTDGDGFIDFNEF 60 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 16/53 (30%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKEL 53 + F + S L EV+ D+DG G ID E Sbjct: 8 IFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEF 60 >2M97-A nrPDB Length = 69 Score = 66.9 bits (162), Expect = 5e-12, Method: Composition-based stats. Identities = 24/68 (35%), Positives = 41/68 (60%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 +EE+ + FR+FD D G I + + GE LTDE++ E+ ++D D +G ++ +EF Sbjct: 2 EEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDEF 61 Query: 163 LKIMKKTN 170 LK+M+ Sbjct: 62 LKMMENVQ 69 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 21/65 (32%), Positives = 39/65 (60%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++E+ E F +FD DG+G ID +E +R G + E++ ++ + D + G+I F++ Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTGEQLTDEDVDEIFGDSDTDKNGRIDFDE 60 Query: 89 FLAVM 93 FL +M Sbjct: 61 FLKMM 65 Score = 36.9 bits (84), Expect = 0.005, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 33/69 (47%), Gaps = 1/69 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+ + DK+ G I +F ++ + E+ T E++ + F D D+ G+I F Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDII-RLTGEQLTDEDVDEIFGDSDTDKNGRIDFD 59 Query: 125 NLKRVANEL 133 ++ + Sbjct: 60 EFLKMMENV 68 Score = 27.2 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 21/33 (63%) Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 ++EEL E D+DG+G ++ EEF I++ T Sbjct: 1 SEEELSECFRIFDKDGNGFIDREEFGDIIRLTG 33 >1QXP-A nrPDB Length = 900 Score = 66.5 bits (161), Expect = 5e-12, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 50/121 (41%), Gaps = 13/121 (10%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + ++ + + Q + F++D SGTI EL A A Sbjct: 779 MVAVMDSDTTGKLGFEEFKYLWNNIKKWQG-----IYKRFETDRSGTIGSNELPGAFEAA 833 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF + + MI + TG + F++F++ + + + + +AFR D + TG+ Sbjct: 834 GFHL-NQHIYSMIIRRYSDETGNMDFDNFISCLVRL-------DAMFRAFRSLDKNGTGQ 885 Query: 121 I 121 I Sbjct: 886 I 886 Score = 56.9 bits (136), Expect = 5e-09, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 67/162 (41%), Gaps = 22/162 (13%) Query: 21 PKPELTEDQKQE-VREAFDLFDSDGSGTIDVKELKVAM----------RALGFEPRKEEM 69 + L+E++ + + F D I VKEL+ + R GF E Sbjct: 523 DEKVLSEEEIDDNFKTLFSKLAGD-DMEISVKELQTILNRIISKHKDLRTNGFSL--ESC 579 Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + M++ +D++ GK+ +F + + L FR FD D++G +S ++ Sbjct: 580 RSMVNLMDRDGNGKLGLVEFNILWNRIRN-------YLTIFRKFDLDKSGSMSAYEMRMA 632 Query: 130 ANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 G L +L ++I D + ++ + F++ + + + Sbjct: 633 IEAAGFKL-PCQLHQVIVARFADDELIIDFDNFVRCLVRLEI 673 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 43/95 (45%), Gaps = 8/95 (8%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 + F FD D SG++ E+++A+ A GF+ + + +++ + I F++F Sbjct: 606 IRNYLTIFRKFDLDKSGSMSAYEMRMAIEAAGFKLPCQLHQVIVARF-ADDELIIDFDNF 664 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 + + + E + K F+ D + TG I Sbjct: 665 VRCLVRL-------EILFKIFKQLDPENTGTIQLD 692 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 24/151 (15%), Positives = 57/151 (37%), Gaps = 17/151 (11%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAM-RALGFEPRK-------EEMKKMISEVDKE 79 +++++ R+ F D + EL + + + P + + M++ +D + Sbjct: 728 EEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 786 Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TGK+ F +F + ++ ++ F+ D +G I L G L Sbjct: 787 TTGKLGFEEF-------KYLWNNIKKWQGIYKRFETDRSGTIGSNELPGAFEAAGFHLNQ 839 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +I D G ++ + F+ + + + Sbjct: 840 HIYSMIIRRY-SDETGNMDFDNFISCLVRLD 869 Score = 34.5 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL--------GESLTDEELQEMI 146 + ++E++ + F D +IS K L+ + N + + E + M+ Sbjct: 525 KVLSEEEIDDNFKTLFSKLAGD-DMEISVKELQTILNRIISKHKDLRTNGFSLESCRSMV 583 Query: 147 DEADRDGDGEVNEEEFLKIMKKTNLY 172 + DRDG+G++ EF + + Y Sbjct: 584 NLMDRDGNGKLGLVEFNILWNRIRNY 609 >1JFJ-A nrPDB Length = 134 Score = 66.1 bits (160), Expect = 8e-12, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 61/133 (45%), Gaps = 6/133 (4%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 F D +G G + +E+K + ++ ++ + +D + G+I N+F Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 94 TQKMAEKDTKEEI--LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + + ++I ++L D D GK++ + + + G E++ E + +AD Sbjct: 63 GSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGI----EKVAEQVMKADA 118 Query: 152 DGDGEVNEEEFLK 164 +GDG + EEFL+ Sbjct: 119 NGDGYITLEEFLE 131 Score = 49.2 bits (116), Expect = 9e-07, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 47/105 (44%), Gaps = 4/105 (3%) Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + + E+D G +S+ + + K ++ + F+ D D G+I + Sbjct: 3 EALFKEIDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 130 ANEL-GESLTDEEL--QEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + G+ L+D+++ + + D DGDG++ +EE KK + Sbjct: 62 YGSIQGQDLSDDKIGLKVLYKLMDVDGDGKLTKEEVTSFFKKHGI 106 Score = 46.5 bits (109), Expect = 7e-06, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 47/114 (41%), Gaps = 10/114 (8%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKEL-KVAMRALGFEPRKEEM--KKM 72 K V K + +Q ++ F D+DG+G ID E K G + +++ K + Sbjct: 23 KAFVSKKRAIKNEQLLQL--IFKSIDADGNGEIDQNEFAKFYGSIQGQDLSDDKIGLKVL 80 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 +D + GK++ + + + EK ++ + D + G I+ + Sbjct: 81 YKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKA-----DANGDGYITLEEF 129 Score = 38.4 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 32/69 (46%), Gaps = 5/69 (7%) Query: 24 ELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGK 83 +L++D+ ++ + L D DG G + +E+ + G E E++ K D G Sbjct: 69 DLSDDKIG-LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMK----ADANGDGY 123 Query: 84 ISFNDFLAV 92 I+ +FL Sbjct: 124 ITLEEFLEF 132 >3BOW-B nrPDB Length = 184 Score = 65.8 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 50/121 (41%), Gaps = 13/121 (10%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + ++ + + Q + FD+D SGTI EL A A Sbjct: 63 MVAVMDSDTTGKLGFEEFKYLWNNIKKWQG-----IYKRFDTDRSGTIGSNELPGAFEAA 117 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF + + MI + TG + F++F++ + + + + +AFR D + TG+ Sbjct: 118 GFHL-NQHIYSMIIRRYSDETGNMDFDNFISCLVRL-------DAMFRAFRSLDKNGTGQ 169 Query: 121 I 121 I Sbjct: 170 I 170 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 57/151 (37%), Gaps = 17/151 (11%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAM-RALGFEPRK-------EEMKKMISEVDKE 79 +++++ R+ F D + EL + + + P + + M++ +D + Sbjct: 12 EEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 70 Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TGK+ F +F + ++ ++ FD D +G I L G L Sbjct: 71 TTGKLGFEEF-------KYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQ 123 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +I D G ++ + F+ + + + Sbjct: 124 HIYSMIIRRY-SDETGNMDFDNFISCLVRLD 153 >3TZ1-A nrPDB Length = 74 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 26/72 (36%), Positives = 43/72 (59%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 E + E+ +AFR+ D ++ G I L+ + LG+ LT++E++ MI E D DG G V+ Sbjct: 2 EDLDERELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVD 61 Query: 159 EEEFLKIMKKTN 170 EEF +M ++ Sbjct: 62 YEEFKCLMMSSD 73 Score = 59.2 bits (142), Expect = 8e-10, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 39/63 (61%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLA 91 E++EAF + D + G I V L+ +++LG E ++E++ MI+E D + +G + + +F Sbjct: 8 ELKEAFRVLDKEKKGVIKVDVLRWILKSLGDELTEDEIENMIAETDTDGSGTVDYEEFKC 67 Query: 92 VMT 94 +M Sbjct: 68 LMM 70 >2K2A-A nrPDB Length = 70 Score = 65.4 bits (158), Expect = 1e-11, Method: Composition-based stats. Identities = 28/69 (40%), Positives = 44/69 (63%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 ++E+ +AFRL+D + G IS ++ + EL E+L+ E+L MIDE D DG G V+ EE Sbjct: 1 MQQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEE 60 Query: 162 FLKIMKKTN 170 F+ +M + Sbjct: 61 FMGVMTGGD 69 Score = 60.0 bits (144), Expect = 6e-10, Method: Composition-based stats. Identities = 23/65 (35%), Positives = 39/65 (60%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 +QE+REAF L+D +G+G I ++ + L E++ MI E+D + +G + F +F Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAELDETLSSEDLDAMIDEIDADGSGTVDFEEF 61 Query: 90 LAVMT 94 + VMT Sbjct: 62 MGVMT 66 Score = 32.2 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 30/66 (45%), Gaps = 1/66 (1%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 ++E+++ DKE G IS + ++ + + E + E++ D D +G + F+ Sbjct: 2 QQELREAFRLYDKEGNGYISTDVMREILAE-LDETLSSEDLDAMIDEIDADGSGTVDFEE 60 Query: 126 LKRVAN 131 V Sbjct: 61 FMGVMT 66 >1DGU-A nrPDB Length = 183 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 11/123 (8%) Query: 56 AMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDD 115 ++ L P KE + ++ S A +SF DFL +++ + AFR+FD Sbjct: 52 SLPELKANPFKERICRVFS--TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDF 109 Query: 116 DETGKISFKNLKRVANEL-GE----SLTDEELQEMID----EADRDGDGEVNEEEFLKIM 166 D+ G ++ ++L R+ N L GE L+ E++++ID E+D D DG +N EF ++ Sbjct: 110 DDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 169 Query: 167 KKT 169 ++ Sbjct: 170 SRS 172 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 11/97 (11%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVRE--AFDLFDSDGSGTIDVKELKVAMRAL-----GF 62 S S++ + ++ +++ AF +FD D GT++ ++L + L Sbjct: 75 KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDT 134 Query: 63 EPRKEEMKKMIS----EVDKEATGKISFNDFLAVMTQ 95 EMK++I E D + G I+ ++F V+++ Sbjct: 135 RLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 171 >5M6C-E nrPDB Length = 193 Score = 65.0 bits (157), Expect = 2e-11, Method: Composition-based stats. Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 19/155 (12%) Query: 26 TEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRAL---GFEPRKEEMKKMISEVDKEAT 81 TE + E++E + F D +G ++V E K G + E + D + Sbjct: 20 TEFSELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAE--HVFRNFDTNSD 77 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR-----------VA 130 G I F +F+ ++ + +++++ AF ++D D G IS + + V Sbjct: 78 GTIDFREFIIALS-VTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQAIYKMVSSVM 136 Query: 131 NELGESLTDEE-LQEMIDEADRDGDGEVNEEEFLK 164 + T E+ +++ + D + DG+++ EEF++ Sbjct: 137 KMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIR 171 Score = 63.8 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 45/116 (38%), Gaps = 11/116 (9%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D + F FD++ GTID +E +A+ ++++ S D + G IS Sbjct: 60 DASKFAEHVFRNFDTNSDGTIDFREFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISRE 119 Query: 88 DFLAV-----------MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + L + M E ++ K FR D + GK+S + R A Sbjct: 120 EMLEIVQAIYKMVSSVMKMPEDESTPEKRTEKIFRQMDTNNDGKLSLEEFIRGAKS 175 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 45/104 (43%), Gaps = 1/104 (0%) Query: 65 RKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + E+++ K+ TG ++ ++F + D + FR FD + G I F Sbjct: 23 SELELQEWYKGFLKDCPTGILNVDEFKKIYANFFPYGDASKFAEHVFRNFDTNSDGTIDF 82 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + + +++L D DG+G ++ EE L+I++ Sbjct: 83 REFIIALSVTSRGRLEQKLMWAFSMYDLDGNGYISREEMLEIVQ 126 >1V1G-A nrPDB Length = 222 Score = 64.6 bits (156), Expect = 2e-11, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 65/161 (40%), Gaps = 11/161 (6%) Query: 17 RKVGPKPELTEDQKQEVREAFDLFDSD--GSGTIDVKELKVAMRALGFEPRKEEMKKMIS 74 + T ++ + + E F S G I +E ++A+ R ++ Sbjct: 23 ELLASVTPFTVEEVEALYELFKKLSSSIIDDGLIHKEEFQLALFR-NRNRRNLFADRIFD 81 Query: 75 EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE-- 132 D + G I F +F+ + E++ AF+L+D +TG I + LK + Sbjct: 82 VFDVKRNGVIEFGEFVRSLGVFHPSAPVHEKVKFAFKLYDLRQTGFIEREELKEMVVALL 141 Query: 133 ------LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 L E + + + + +ADR DG+++ +E+ + Sbjct: 142 HESELVLSEDMIEVMVDKAFVQADRKNDGKIDIDEWKDFVS 182 >2JUL-A nrPDB Length = 256 Score = 64.2 bits (155), Expect = 2e-11, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 65/162 (40%), Gaps = 18/162 (11%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKK--MISEVDK 78 + + T+ + Q + F + +G +D K+ F + + D Sbjct: 84 AQTKFTKKELQSLYRGFK--NECPTGLVDEDTFKLIYSQF-FPQGDATTYAHFLFNAFDA 140 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN----ELG 134 + G I F DF+ ++ + E++ AF L+D ++ G I+ + + + +G Sbjct: 141 DGNGAIHFEDFVVGLS-ILLRGTVHEKLKWAFNLYDINKDGCITKEEMLAIMKSIYDMMG 199 Query: 135 --------ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 E E ++ + DR+ DG V +EFL+ +K Sbjct: 200 RHTYPILREDAPLEHVERFFQKMDRNQDGVVTIDEFLETCQK 241 >2JU0-A nrPDB Length = 190 Score = 64.2 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 39/103 (37%), Gaps = 11/103 (10%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQK 96 F +FD D +G I +E + +E++ D G I+F++ L ++ Sbjct: 69 FTVFDKDNNGFIHFEEFITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVASV 128 Query: 97 -----------MAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 E + + K F+L D +E G I+ + Sbjct: 129 YKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFRE 171 Score = 62.3 bits (150), Expect = 1e-10, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 59/133 (44%), Gaps = 14/133 (10%) Query: 45 SGTIDVKELKVAMRAL-GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK 103 SG + ++ + F ++ + + DK+ G I F +F+ V++ + + Sbjct: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLST-TSRGTLE 98 Query: 104 EEILKAFRLFDDDETGKISFKNL----KRVANELGESLTDEE--------LQEMIDEADR 151 E++ AF L+D + G I+F + V +G +T E ++++ D+ Sbjct: 99 EKLSWAFELYDLNHDGYITFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDK 158 Query: 152 DGDGEVNEEEFLK 164 + DG + +EF + Sbjct: 159 NEDGYITLDEFRE 171 Score = 58.4 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 44/101 (43%), Gaps = 1/101 (0%) Query: 68 EMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E+++ ++ +G+++ DF+ + Q ++ F +FD D G I F+ Sbjct: 26 EIQQWHKGFLRDCPSGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEF 85 Query: 127 KRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 V + +E+L + D + DG + +E L I+ Sbjct: 86 ITVLSTTSRGTLEEKLSWAFELYDLNHDGYITFDEMLTIVA 126 Score = 36.1 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 24/56 (42%), Gaps = 3/56 (5%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQ---KQEVREAFDLFDSDGSGTIDVKELKVA 56 TF + S + +G L ED+ + V++ F L D + G I + E + Sbjct: 117 TFDEMLTIVASVYKMMGSMVTLNEDEATPEMRVKKIFKLMDKNEDGYITLDEFREG 172 Score = 29.9 bits (66), Expect = 0.55, Method: Composition-based stats. Identities = 9/54 (16%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 118 TGKISFKNLKRVANELGESLTDEELQE-MIDEADRDGDGEVNEEEFLKIMKKTN 170 +G+++ ++ ++ + + E+ + D+D +G ++ EEF+ ++ T+ Sbjct: 40 SGQLAREDFVKIYKQFFPFGSPEDFANHLFTVFDKDNNGFIHFEEFITVLSTTS 93 >1S6J-A nrPDB Length = 87 Score = 64.2 bits (155), Expect = 3e-11, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 41/71 (57%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 L+E++ ++E F + D+D SGTI ELK ++ +G E + E+K ++ D + +G I Sbjct: 17 LSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADIDKSGTI 76 Query: 85 SFNDFLAVMTQ 95 + +F+A Sbjct: 77 DYGEFIAATVH 87 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 24/73 (32%), Positives = 43/73 (58%), Gaps = 3/73 (4%) Query: 95 QKMAEKDTKEEI---LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 + MAE+ ++EEI + F++ D D +G I+F LK +G L + E+++++D AD Sbjct: 11 KHMAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSELMESEIKDLMDAADI 70 Query: 152 DGDGEVNEEEFLK 164 D G ++ EF+ Sbjct: 71 DKSGTIDYGEFIA 83 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 38/85 (44%), Gaps = 9/85 (10%) Query: 45 SGTIDVKELKVAMRALGFEPRKEEM---KKMISEVDKEATGKISFNDFLAVMTQKMAEKD 101 SG ID + + + +EE+ K++ +D + +G I+F++ + + +E Sbjct: 3 SGHIDDDD-----KHMAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVGSEL- 56 Query: 102 TKEEILKAFRLFDDDETGKISFKNL 126 + EI D D++G I + Sbjct: 57 MESEIKDLMDAADIDKSGTIDYGEF 81 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 20/41 (48%), Gaps = 3/41 (7%) Query: 133 LGESLTDEEL---QEMIDEADRDGDGEVNEEEFLKIMKKTN 170 + E L++EE+ +E+ D D G + +E +K+ Sbjct: 13 MAERLSEEEIGGLKELFKMIDTDNSGTITFDELKDGLKRVG 53 >3SIA-A nrPDB Length = 220 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 25/131 (19%), Positives = 45/131 (34%), Gaps = 7/131 (5%) Query: 11 ASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMK 70 S + DQ + + F D D SGT+++ EL + G + Sbjct: 31 PSVRNTWWFPLLNTIPLDQYTRIYQWFMGVDRDRSGTLEINELMMGQFPGGIRLSPQTAL 90 Query: 71 KMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 +M+ D + G ISF +F+A+ E F + +G + + Sbjct: 91 RMMRIFDTDFNGHISFYEFMAMY-------KFMELAYNLFVMNARARSGTLEPHEILPAL 143 Query: 131 NELGESLTDEE 141 +LG + Sbjct: 144 QQLGFYINQRT 154 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 27/62 (43%), Gaps = 4/62 (6%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANEL--GESLTDEELQEMIDEADRDGDGEVNEEEFL 163 I + F D D +G + L + + G L+ + M+ D D +G ++ EF+ Sbjct: 53 IYQWFMGVDRDRSGTLEINEL--MMGQFPGGIRLSPQTALRMMRIFDTDFNGHISFYEFM 110 Query: 164 KI 165 + Sbjct: 111 AM 112 >2LM5-A nrPDB Length = 214 Score = 63.8 bits (154), Expect = 3e-11, Method: Composition-based stats. Identities = 36/123 (29%), Positives = 64/123 (52%), Gaps = 11/123 (8%) Query: 56 AMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDD 115 ++ L P KE + ++ S A +SF DFL +++ + AFR+FD Sbjct: 83 SLPELKANPFKERICRVFS--TSPAKDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDF 140 Query: 116 DETGKISFKNLKRVANEL-GE----SLTDEELQEMID----EADRDGDGEVNEEEFLKIM 166 D+ G ++ ++L R+ N L GE L+ E++++ID E+D D DG +N EF ++ Sbjct: 141 DDDGTLNREDLSRLVNCLTGEGEDTRLSASEMKQLIDNILEESDIDRDGTINLSEFQHVI 200 Query: 167 KKT 169 ++ Sbjct: 201 SRS 203 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 11/97 (11%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVRE--AFDLFDSDGSGTIDVKELKVAMRAL-----GF 62 S S++ + ++ +++ AF +FD D GT++ ++L + L Sbjct: 106 KDSLSFEDFLDLLSVFSDTATPDIKSHYAFRIFDFDDDGTLNREDLSRLVNCLTGEGEDT 165 Query: 63 EPRKEEMKKMIS----EVDKEATGKISFNDFLAVMTQ 95 EMK++I E D + G I+ ++F V+++ Sbjct: 166 RLSASEMKQLIDNILEESDIDRDGTINLSEFQHVISR 202 >3AKA-A nrPDB Length = 166 Score = 63.8 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 62/157 (39%), Gaps = 23/157 (14%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKEL----KVAMRALGFEPRKEEMKKMISE-------- 75 + ++ + F FD DG+G ID + K + G R + + + Sbjct: 1 EYERRIAARFTTFDQDGNGHIDRSDFSGAAKALLAEFGVAARSDRGQALYGGAEALWQGL 60 Query: 76 ---VDKEATGKISFNDFLA-VMTQKMAEKDTKEEILKAFR-----LFDDDETGKISFKNL 126 D++ +I+ +F+ + + + D EI + F + D D G ++ + Sbjct: 61 AGIADRDGDQRITREEFVTGAVKRLRDKPDRFAEIARPFLHAALGVADTDGDGAVTVADT 120 Query: 127 KRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 R G + ++ ++ D DGDG+V E E + Sbjct: 121 ARALTAFG--VPEDLARQAAAALDTDGDGKVGETEIV 155 >1C7W-A nrPDB Length = 81 Score = 63.8 bits (154), Expect = 4e-11, Method: Composition-based stats. Identities = 30/71 (42%), Positives = 49/71 (69%), Gaps = 1/71 (1%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGE-SLTDEELQEMIDEADRDGDGEVN 158 +D +EEIL+AF++FD + G I F K + ++GE LTD E++E + EAD DG+G ++ Sbjct: 4 QDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVID 63 Query: 159 EEEFLKIMKKT 169 EF+ ++KK+ Sbjct: 64 IPEFMDLIKKS 74 Score = 57.3 bits (137), Expect = 4e-09, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEP-RKEEMKKMISEVDKEATGK 83 + +D ++E+ AF +FD++G G ID E K M+ +G EP E+++ + E D++ G Sbjct: 2 VRQDDEEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGV 61 Query: 84 ISFNDFLAVMTQKMA 98 I +F+ ++ + Sbjct: 62 IDIPEFMDLIKKSKN 76 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 32/75 (42%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 +EE+ + D G I F++F +M + E T E+ +A + D+D G I Sbjct: 7 EEEILRAFKVFDANGDGVIDFDEFKFIMQKVGEEPLTDAEVEEAMKEADEDGNGVIDIPE 66 Query: 126 LKRVANELGESLTDE 140 + + +L + Sbjct: 67 FMDLIKKSKNALKES 81 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 18/33 (54%) Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +EE+ D +GDG ++ +EF IM+K Sbjct: 6 DEEEILRAFKVFDANGDGVIDFDEFKFIMQKVG 38 >2LVK-A nrPDB Length = 77 Score = 63.4 bits (153), Expect = 4e-11, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 35/63 (55%), Gaps = 1/63 (1%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 +++ + F+ FD + GKIS L LG + + +E+Q M+ E D DGDG ++ EF+ Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNEFI 60 Query: 164 KIM 166 Sbjct: 61 SFC 63 Score = 59.2 bits (142), Expect = 8e-10, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 38/63 (60%), Gaps = 1/63 (1%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 ++ F FD++G G I + EL A+R LG +E+++M++E+D + G I FN+F+ Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDALRTLGST-SADEVQRMMAEIDTDGDGFIDFNEFI 60 Query: 91 AVM 93 + Sbjct: 61 SFC 63 Score = 33.0 bits (74), Expect = 0.062, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 ++M+++ D GKIS ++ + + + +E+ + D D G I F Sbjct: 2 DDMERIFKRFDTNGDGKISLSELTDAL--RTLGSTSADEVQRMMAEIDTDGDGFIDFNEF 59 Score = 27.6 bits (60), Expect = 2.5, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 16/53 (30%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKEL 53 + F + S L EV+ D+DG G ID E Sbjct: 7 IFKRFDTNGDGKISLSELTDALRTLGSTSADEVQRMMAEIDTDGDGFIDFNEF 59 >1H4B-A nrPDB Length = 84 Score = 63.4 bits (153), Expect = 4e-11, Method: Composition-based stats. Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 1/68 (1%) Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 K E + F+ FD + GKIS L LG S+T +E++ M+ E D DGDG Sbjct: 2 DDHPQDKAERERIFKRFDANGDGKISAAELGEALKTLG-SITPDEVKHMMAEIDTDGDGF 60 Query: 157 VNEEEFLK 164 ++ +EF Sbjct: 61 ISFQEFTD 68 Score = 58.4 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 23/60 (38%), Positives = 34/60 (56%), Gaps = 1/60 (1%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 K E F FD++G G I EL A++ LG +E+K M++E+D + G ISF +F Sbjct: 8 KAERERIFKRFDANGDGKISAAELGEALKTLG-SITPDEVKHMMAEIDTDGDGFISFQEF 66 Score = 29.5 bits (65), Expect = 0.80, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 18/59 (30%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 + F + S L EV+ D+DG G I +E RA Sbjct: 14 IFKRFDANGDGKISAAELGEALKTLGSITPDEVKHMMAEIDTDGDGFISFQEFTDFGRA 72 >1OZS-A nrPDB Length = 73 Score = 63.1 bits (152), Expect = 5e-11, Method: Composition-based stats. Identities = 22/71 (30%), Positives = 46/71 (64%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 + ++EE+ FR+FD + G I + LK + GE++T+++++E++ + D++ DG ++ Sbjct: 2 KGKSEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRID 61 Query: 159 EEEFLKIMKKT 169 +EFL+ MK Sbjct: 62 YDEFLEFMKGV 72 Score = 56.5 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 43/65 (66%) Query: 29 QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND 88 ++E+ + F +FD + G ID++ELK+ ++A G ++++++++ + DK G+I +++ Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEELKIMLQATGETITEDDIEELMKDGDKNNDGRIDYDE 64 Query: 89 FLAVM 93 FL M Sbjct: 65 FLEFM 69 Score = 36.1 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 16/67 (23%), Positives = 29/67 (43%), Gaps = 1/67 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +EE+ + DK A G I + L +M Q E T+++I + + D + G+I + Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEE-LKIMLQATGETITEDDIEELMKDGDKNNDGRIDYD 63 Query: 125 NLKRVAN 131 Sbjct: 64 EFLEFMK 70 Score = 26.1 bits (56), Expect = 8.1, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 20/33 (60%) Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 ++EEL ++ D++ DG ++ EE +++ T Sbjct: 5 SEEELSDLFRMFDKNADGYIDLEELKIMLQATG 37 >2OPO-A nrPDB Length = 86 Score = 62.7 bits (151), Expect = 8e-11, Method: Composition-based stats. Identities = 22/58 (37%), Positives = 33/58 (56%), Gaps = 1/58 (1%) Query: 107 LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + F+ FD + GKIS L LG S+T +E++ M+ E D DGDG ++ +EF Sbjct: 14 ERIFKRFDTNGDGKISSSELGDALKTLG-SVTPDEVRRMMAEIDTDGDGFISFDEFTD 70 Score = 60.0 bits (144), Expect = 5e-10, Method: Composition-based stats. Identities = 21/64 (32%), Positives = 36/64 (56%), Gaps = 1/64 (1%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 T + F FD++G G I EL A++ LG +E+++M++E+D + G IS Sbjct: 6 TPQDIADRERIFKRFDTNGDGKISSSELGDALKTLG-SVTPDEVRRMMAEIDTDGDGFIS 64 Query: 86 FNDF 89 F++F Sbjct: 65 FDEF 68 Score = 29.5 bits (65), Expect = 0.69, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 17/59 (28%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 + F + S L EVR D+DG G I E RA Sbjct: 16 IFKRFDTNGDGKISSSELGDALKTLGSVTPDEVRRMMAEIDTDGDGFISFDEFTDFARA 74 >2L2E-A nrPDB Length = 190 Score = 61.9 bits (149), Expect = 1e-10, Method: Composition-based stats. Identities = 32/169 (18%), Positives = 77/169 (45%), Gaps = 26/169 (15%) Query: 21 PKPELTEDQ-----------KQEVREAFDLFDSD-GSGTIDVKELKVAMRAL-GFEPRKE 67 + +L++DQ K+E+++ + F D SG ++ E + + F Sbjct: 4 SQSKLSQDQLQDLVRSTRFDKKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSA 63 Query: 68 EMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLK 127 + + + D + G I F +F+ ++ + + ++++ AF+L+D D G IS+ + Sbjct: 64 FAEYVFNVFDADKNGYIDFKEFICALS-VTSRGELNDKLIWAFQLYDLDNNGLISYDEML 122 Query: 128 RV----ANELGESLT--------DEELQEMIDEADRDGDGEVNEEEFLK 164 R+ +G + ++ + ++ + D++ DG++ EEF + Sbjct: 123 RIVDAIYKMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEFCE 171 Score = 59.2 bits (142), Expect = 9e-10, Method: Composition-based stats. Identities = 25/121 (20%), Positives = 54/121 (44%), Gaps = 3/121 (2%) Query: 47 TIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEE 105 + +L+ +R+ F+ K+E+++ K+ +G ++ ++F + Q D Sbjct: 7 KLSQDQLQDLVRSTRFD--KKELQQWYKGFFKDCPSGHLNKSEFQKIYKQFFPFGDPSAF 64 Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 F +FD D+ G I FK + +++L D D +G ++ +E L+I Sbjct: 65 AEYVFNVFDADKNGYIDFKEFICALSVTSRGELNDKLIWAFQLYDLDNNGLISYDEMLRI 124 Query: 166 M 166 + Sbjct: 125 V 125 Score = 32.6 bits (73), Expect = 0.097, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 22/40 (55%), Gaps = 3/40 (7%) Query: 17 RKVGPKPELTEDQ---KQEVREAFDLFDSDGSGTIDVKEL 53 + VG +L ED+ ++ V + F++ D + G + ++E Sbjct: 130 KMVGSMVKLPEDEDTPEKRVNKIFNMMDKNKDGQLTLEEF 169 >2Q4U-A nrPDB Length = 272 Score = 61.9 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 33/164 (20%), Positives = 67/164 (40%), Gaps = 30/164 (18%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEP------RKEEMKKM----ISEVDKEATG 82 + + FD+D +G I+ KEL R + + E ++++ +S D G Sbjct: 13 FLQIWQHFDADDNGYIEGKELDDFFRHMLKKLQPKDKITDERVQQIKKSFMSAYDATFDG 72 Query: 83 KISFND-----------FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN 131 ++ + FL + ++ ++ E +K +R +D D +G IS LK Sbjct: 73 RLQIEELANMILPQEENFLLIFRREAPLDNSVE-FMKIWRKYDADSSGYISAAELKNFLK 131 Query: 132 EL--------GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +L + DE M+ D++ DG ++ + +I+ Sbjct: 132 DLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILA 175 Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 60/157 (38%), Gaps = 27/157 (17%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGF--------EPRKEEMKKMISEVDKEATGK 83 E + + +D+D SG I ELK ++ L E M+ DK G+ Sbjct: 105 EFMKIWRKYDADSSGYISAAELKNFLKDLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGR 164 Query: 84 ISFNDFLAVMT-----------QKMAEKDTKEEILKAFRLFDDDETGKISFKN----LKR 128 + ND ++ ++ + K + K F +D TG + +K Sbjct: 165 LDLNDLARILALQENFLLQFKMDASSQVERKRDFEKIFAHYDVSRTGALEGPEVDGFVKD 224 Query: 129 VANELGESLTDEELQE----MIDEADRDGDGEVNEEE 161 + + S++ +L + ++ D + DG++ + E Sbjct: 225 MMELVRPSISGGDLDKFRECLLTHCDMNKDGKIQKSE 261 Score = 34.9 bits (79), Expect = 0.018, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 49/131 (37%), Gaps = 20/131 (15%) Query: 16 KRKVGPKPELTEDQKQEVREAF-DLFDSDGSGTIDVKELKVA------------MRALGF 62 + K ++ ++ E +A +FD + G +D+ +L M A Sbjct: 132 DLFLQHKKKIPPNKLDEYTDAMMKIFDKNKDGRLDLNDLARILALQENFLLQFKMDASSQ 191 Query: 63 EPRKEEMKKMISEVDKEATGKISFND---FLAVMTQKMAEKDTKEEILK----AFRLFDD 115 RK + +K+ + D TG + + F+ M + + + ++ K D Sbjct: 192 VERKRDFEKIFAHYDVSRTGALEGPEVDGFVKDMMELVRPSISGGDLDKFRECLLTHCDM 251 Query: 116 DETGKISFKNL 126 ++ GKI L Sbjct: 252 NKDGKIQKSEL 262 >2FCE-A nrPDB Length = 70 Score = 61.5 bits (148), Expect = 2e-10, Method: Composition-based stats. Identities = 23/61 (37%), Positives = 43/61 (70%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 E+ +KAF++FD + TGK+S +L+ + LGE LTD E+ E++ + D +GE++ ++F+ Sbjct: 5 EDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKFI 64 Query: 164 K 164 + Sbjct: 65 E 65 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 35/62 (56%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 ++ +AF +FD + +G + V +L+ + LG + E+ +++ V+ ++ G+I + F Sbjct: 4 TEDFVKAFQVFDKESTGKVSVGDLRYMLTGLGEKLTDAEVDELLKGVEVDSNGEIDYKKF 63 Query: 90 LA 91 + Sbjct: 64 IE 65 >2D8N-A nrPDB Length = 207 Score = 61.1 bits (147), Expect = 2e-10, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 50/116 (43%), Gaps = 3/116 (2%) Query: 54 KVAMRALGFE--PRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 K + L +EE+ K+ TG+I+ F ++ + + D K F Sbjct: 18 KEILEELQLNTKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDPKAYAQHVF 77 Query: 111 RLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 R FD + G + FK + T+++L+ D DG+G +++ E L+I+ Sbjct: 78 RSFDSNLDGTLDFKEYVIALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIV 133 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 26/156 (16%), Positives = 64/156 (41%), Gaps = 19/156 (12%) Query: 26 TEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRA--LGFEPRKEEMKKMISEVDKEATG 82 T+ ++E+ + F D +G I ++ + +P K + + D G Sbjct: 28 TKFSEEELCSWYQSFLKDCPTGRITQQQFQSIYAKFFPDTDP-KAYAQHVFRSFDSNLDG 86 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEEL 142 + F +++ + T +++ AF L+D D G IS + + + + +T E++ Sbjct: 87 TLDFKEYV-IALHMTTAGKTNQKLEWAFSLYDVDGNGTISKNEVLEIVMAIFKMITPEDV 145 Query: 143 --------------QEMIDEADRDGDGEVNEEEFLK 164 +++ ++ D ++ E+EF++ Sbjct: 146 KLLPDDENTPEKRAEKIWKYFGKNDDDKLTEKEFIE 181 >2ZFD-A nrPDB Length = 226 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 72/157 (45%), Gaps = 17/157 (10%) Query: 25 LTEDQKQEVREAFD-----LFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKE 79 + + + + E F + D G I+ +E ++A+ + ++ D + Sbjct: 42 FSVSEIEALYELFKKISSAVID---DGLINKEEFQLALFKTN-KKESLFADRVFDLFDTK 97 Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV----ANELGE 135 G + F +F ++ ++I +F+L+D + G I + +K++ E G Sbjct: 98 HNGILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGM 157 Query: 136 SLTDEELQEMID----EADRDGDGEVNEEEFLKIMKK 168 +L D ++++ID EAD DG++++EE+ ++ + Sbjct: 158 NLKDTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 194 >3MSE-B nrPDB Length = 180 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 27/171 (15%), Positives = 73/171 (42%), Gaps = 14/171 (8%) Query: 4 TFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE 63 ++ K + + + + + + + E F D++ +G++ +E+ + ++G Sbjct: 12 SYMKHSNIRNIIINIMAHELSVINNHIKYINELFYKLDTNHNGSLSHREIYTVLASVGI- 70 Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 +K ++ +++ +D G I++ +F+A + + T + AF D DE G IS Sbjct: 71 -KKWDINRILQALDINDRGNITYTEFMAGCYRWKNIEST--FLKAAFNKIDKDEDGYISK 127 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDG--------EVNEEEFLKIM 166 ++ + ++ + L + ++ G +++ +EF M Sbjct: 128 SDIVSLVHD--KVLDNNDIDNFFLSVHSIKKGIPREHIINKISFQEFKDYM 176 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 15/101 (14%), Positives = 31/101 (30%), Gaps = 10/101 (9%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 + ++ + +Y + + ++ AF+ D D G I ++ + Sbjct: 78 ILQALDINDRGNITYTEFMAGCYRWKNIESTFLKAAFNKIDKDEDGYISKSDIVSLVH-- 135 Query: 61 GFEPRKEEMKKMISEVDKEATG--------KISFNDFLAVM 93 ++ V G KISF +F M Sbjct: 136 DKVLDNNDIDNFFLSVHSIKKGIPREHIINKISFQEFKDYM 176 >2VTG-A nrPDB Length = 150 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 28/92 (30%), Positives = 42/92 (45%), Gaps = 6/92 (6%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 ++ +E + FD + G ID+ LK M LG EMKKMISEV + IS+ Sbjct: 46 PEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKKMISEVTGGVSDTISY 105 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDET 118 DF+ +M + +LK +F+ Sbjct: 106 RDFVNMM------LGKRSAVLKLVMMFEGKAN 131 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 37/82 (45%), Gaps = 2/82 (2%) Query: 87 NDFL--AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE 144 +FL + + + + + FD + G+I +LKR+ +LG T E+++ Sbjct: 31 REFLCDQKYSDEENLPEKLTAFKEKYMEFDLNNEGEIDLMSLKRMMEKLGVPKTHLEMKK 90 Query: 145 MIDEADRDGDGEVNEEEFLKIM 166 MI E ++ +F+ +M Sbjct: 91 MISEVTGGVSDTISYRDFVNMM 112 >4OKH-A nrPDB Length = 189 Score = 60.4 bits (145), Expect = 4e-10, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 51/133 (38%), Gaps = 13/133 (9%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + + + ++ QK F +D+D SGTI+ E++ A+ Sbjct: 60 MIALMDTDGSGKLNLQEFHHLWNKIKAWQK-----IFKHYDTDQSGTINSYEMRNAVNDA 114 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF + + +I+ + I F+ F+ + E + +AF FD D G Sbjct: 115 GFHLNNQ-LYDIITMRYADKHMNIDFDSFICCFVRL-------EGMFRAFHAFDKDGDGI 166 Query: 121 ISFKNLKRVANEL 133 I L+ + + Sbjct: 167 IKLNVLEWLQLTM 179 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 33/161 (20%), Positives = 67/161 (41%), Gaps = 22/161 (13%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL----------GFEPRKEE 68 +G + +E+Q Q+ R F D I ELK + + GF E Sbjct: 1 MGSSDQESEEQ-QQFRNIFKQIAGD-DMEICADELKKVLNTVVNKHKDLKTHGF--TLES 56 Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 + MI+ +D + +GK++ +F + + K F+ +D D++G I+ ++ Sbjct: 57 CRSMIALMDTDGSGKLNLQEF-------HHLWNKIKAWQKIFKHYDTDQSGTINSYEMRN 109 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 N+ G L ++ L ++I D ++ + F+ + Sbjct: 110 AVNDAGFHLNNQ-LYDIITMRYADKHMNIDFDSFICCFVRL 149 >5XND-A nrPDB Length = 114 Score = 60.0 bits (144), Expect = 5e-10, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 44/108 (40%), Gaps = 8/108 (7%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + E+ + A G F + +E+ KAF + D D++G I Sbjct: 12 LKDAEVTAALDGCK--AAGSFDHKKFFKACG---LSGKSTDEVKKAFAIIDQDKSGFIEE 66 Query: 124 KNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + LK +L+D E + + D DGDG++ +EF ++K Sbjct: 67 EELKLFLQNFKAGARALSDAETKAFLKAGDSDGDGKIGIDEFAAMIKG 114 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 35/71 (49%), Gaps = 3/71 (4%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEPRKEEMKKMISEVDKEAT 81 L+ EV++AF + D D SG I+ +ELK+ ++ E K + D + Sbjct: 41 LSGKSTDEVKKAFAIIDQDKSGFIEEEELKLFLQNFKAGARALSDAETKAFLKAGDSDGD 100 Query: 82 GKISFNDFLAV 92 GKI ++F A+ Sbjct: 101 GKIGIDEFAAM 111 >2G2B-A nrPDB Length = 150 Score = 59.6 bits (143), Expect = 6e-10, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 + +E + FD +G+G ID+ LK + LG E+KK+I EV + S+ DFL Sbjct: 51 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFL 110 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDD 115 +M + ILK ++++ Sbjct: 111 RMM------LGKRSAILKMILMYEE 129 Score = 43.8 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + E + + FD + G I +LKR+ +LG T EL+++I E Sbjct: 40 YSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSG 99 Query: 153 GDGEVNEEEFLKIM 166 + +FL++M Sbjct: 100 SGETFSYPDFLRMM 113 >1UHN-A nrPDB Length = 189 Score = 58.4 bits (140), Expect = 2e-09, Method: Composition-based stats. Identities = 31/154 (20%), Positives = 71/154 (46%), Gaps = 11/154 (7%) Query: 25 LTEDQKQEVREAFDLFDSD--GSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 + + + + E F S G I+ +E ++A+ + ++ D + G Sbjct: 11 FSVSEIEALYELFKKISSAVIDDGLINKEEFQLALFKTN-KKESLFADRVFDLFDTKHNG 69 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV----ANELGESLT 138 + F +F ++ ++I +F+L+D + G I + +K++ E G +L Sbjct: 70 ILGFEEFARALSVFHPNAPIDDKIHFSFQLYDLKQQGFIERQEVKQMVVATLAESGMNLK 129 Query: 139 DEELQEMID----EADRDGDGEVNEEEFLKIMKK 168 D ++++ID EAD DG++++EE+ ++ + Sbjct: 130 DTVIEDIIDKTFEEADTKHDGKIDKEEWRSLVLR 163 >5VT9-A nrPDB Length = 152 Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 28/140 (20%), Positives = 59/140 (42%), Gaps = 7/140 (5%) Query: 28 DQKQEVREAFDLFDSDGSG-TIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 ++ E E + F++ SG + + + R LG P + ++++ + + Sbjct: 14 EEMVEADEMYARFNARASGGKVSTGDAMILARQLGLAPSYAD----KQAFEEKSGDNLDY 69 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 F + +D E++++AF FD + G ++ K + + GE LT EE + Sbjct: 70 ASFQKFVGTSTHPEDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTEEFNALA 129 Query: 147 DEADRDGDGEVNEEEFLKIM 166 E +++ +F K M Sbjct: 130 AEYFTSD--QIDYRQFCKAM 147 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 37/87 (42%), Gaps = 3/87 (3%) Query: 9 NVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE 68 N+ S+++ VG ED +++ EAF FD G + K++ + G EE Sbjct: 66 NLDYASFQKFVGTSTH-PEDNIEDLVEAFAYFDVSKHGYLTRKQMGNILMTYGEPLTTEE 124 Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQ 95 + +E + +I + F M + Sbjct: 125 FNALAAEY--FTSDQIDYRQFCKAMLE 149 >1QX2-A nrPDB Length = 76 Score = 58.0 bits (139), Expect = 2e-09, Method: Composition-based stats. Identities = 34/75 (45%), Positives = 44/75 (58%), Gaps = 4/75 (5%) Query: 100 KDTKEEILKAFRLFDDDE--TGKISFKNLKRVANELGESLTD--EELQEMIDEADRDGDG 155 + EEI AF +F E +IS + LK V LG SL L EMI+E D++GDG Sbjct: 1 MKSPEEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDG 60 Query: 156 EVNEEEFLKIMKKTN 170 EV+ EEFL +MKK + Sbjct: 61 EVSFEEFLVMMKKIS 75 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 25/72 (34%), Positives = 41/72 (56%), Gaps = 4/72 (5%) Query: 31 QEVREAFDLFD-SDGS-GTIDVKELKVAMRALGFEPRK--EEMKKMISEVDKEATGKISF 86 +E++ AF++F +G I +ELK+ M+ LG K + +MI EVDK G++SF Sbjct: 5 EEIKGAFEVFAAKEGDPNQISKEELKLVMQTLGPSLLKGMSTLDEMIEEVDKNGDGEVSF 64 Query: 87 NDFLAVMTQKMA 98 +FL +M + Sbjct: 65 EEFLVMMKKISQ 76 >2LCP-A nrPDB Length = 190 Score = 57.7 bits (138), Expect = 2e-09, Method: Composition-based stats. Identities = 33/174 (18%), Positives = 74/174 (42%), Gaps = 22/174 (12%) Query: 10 VASTSYKRKVGPKPELTEDQ---KQEVREAFDLFDSD-GSGTIDVKELKVAMRAL---GF 62 + ++ K K ELT ++EV++ + F D SG +D + + G Sbjct: 1 MGKSNSKLKPEVVEELTRKTYFTEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGD 60 Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKIS 122 + + + D+ G+I F++F+ ++ + E++ AF+L+D D G I+ Sbjct: 61 PTKFATF--VFNVFDENKDGRIEFSEFIQALS-VTSRGTLDEKLRWAFKLYDLDNDGYIT 117 Query: 123 FKNLKRV----ANELG--------ESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + + +G E+ ++ + + D++ DG++ +EF + Sbjct: 118 RNEMLDIVDAIYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQE 171 Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 44/103 (42%), Gaps = 1/103 (0%) Query: 65 RKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 ++E+++ K+ +G++ F + Q D + F +FD+++ G+I F Sbjct: 23 TEKEVQQWYKGFIKDCPSGQLDAAGFQKIYKQFFPFGDPTKFATFVFNVFDENKDGRIEF 82 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + + DE+L+ D D DG + E L I+ Sbjct: 83 SEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIV 125 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 40/102 (39%), Gaps = 13/102 (12%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQE-VREAFDLFDSDGSGTIDVKELKVAMRA 59 + + F ++ + + + E +R AF L+D D G I E+ + A Sbjct: 68 VFNVFDENKDGRIEFSEFIQALSVTSRGTLDEKLRWAFKLYDLDNDGYITRNEMLDIVDA 127 Query: 60 LGF------------EPRKEEMKKMISEVDKEATGKISFNDF 89 + ++ + ++ + +DK A GK++ +F Sbjct: 128 IYQMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEF 169 Score = 32.2 bits (72), Expect = 0.13, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 22/46 (47%), Gaps = 3/46 (6%) Query: 17 RKVGPKPELTEDQK---QEVREAFDLFDSDGSGTIDVKELKVAMRA 59 + VG EL E++ + V F + D + G + ++E + +A Sbjct: 130 QMVGNTVELPEEENTPEKRVDRIFAMMDKNADGKLTLQEFQEGSKA 175 >1WY9-A nrPDB Length = 147 Score = 57.3 bits (137), Expect = 3e-09, Method: Composition-based stats. Identities = 22/88 (25%), Positives = 42/88 (47%), Gaps = 6/88 (6%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 + + + FD +G+G ID+ LK + LG E+K++I EV + S++DFL Sbjct: 48 EAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSGSEETFSYSDFL 107 Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDET 118 +M + IL+ ++++ Sbjct: 108 RMM------LGKRSAILRMILMYEEKNK 129 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 31/74 (41%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + E + FD + G I +LKR+ +LG T EL+ +I E Sbjct: 37 YSNDEDLPSKLEAFKVKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKRLIREVSSG 96 Query: 153 GDGEVNEEEFLKIM 166 + + +FL++M Sbjct: 97 SEETFSYSDFLRMM 110 >3DD4-A nrPDB Length = 229 Score = 56.9 bits (136), Expect = 4e-09, Method: Composition-based stats. Identities = 27/163 (16%), Positives = 67/163 (41%), Gaps = 20/163 (12%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA---LGFEPRKEEMKKMISEVD 77 + + T+ + Q + F + SG ++ + K G + + D Sbjct: 57 AQSKFTKKELQILYRGFK--NECPSGVVNEETFKEIYSQFFPQGDSTTYAHF--LFNAFD 112 Query: 78 KEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESL 137 + G +SF DF+ ++ + +E++ AF L+D ++ G I+ + + + + + + Sbjct: 113 TDHNGAVSFEDFIKGLS-ILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKAIYDMM 171 Query: 138 TD------------EELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + ++ + D++ DG V +EF++ +K Sbjct: 172 GKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQK 214 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 48/123 (39%), Gaps = 13/123 (10%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQE-VREAFDLFDSDGSGTIDVKELKVAMRA 59 + + F + + S++ + L QE + AF+L+D + G I +E+ M+A Sbjct: 107 LFNAFDTDHNGAVSFEDFIKGLSILLRGTVQEKLNWAFNLYDINKDGYITKEEMLDIMKA 166 Query: 60 ------------LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEIL 107 L + ++ ++ ++DK G ++ ++F+ + + + Sbjct: 167 IYDMMGKCTYPVLKEDAPRQHVETFFQKMDKNKDGVVTIDEFIESCQKDENIMRSMQLFE 226 Query: 108 KAF 110 Sbjct: 227 NVI 229 >1NYA-A nrPDB Length = 176 Score = 56.5 bits (135), Expect = 5e-09, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 61/155 (39%), Gaps = 24/155 (15%) Query: 31 QEVREAFDLFDSDGSGTIDV----KELKVAMRALGFEPRKEEMKKMIS-----------E 75 +++ FD +D DG+G ++ KE + A G + E++ + + E Sbjct: 7 DRLKKRFDRWDFDGNGALERADFEKEAQHIAEAFGKDAGAAEVQTLKNAFGGLFDYLAKE 66 Query: 76 VDKEATGKISFNDFLAVM-------TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 + G ++ F+ V + + + + D + G+I+ Sbjct: 67 AGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGIVGMCDKNADGQINADEFAA 126 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 LG ++ E E ++ D +G+GE++ +E L Sbjct: 127 WLTALG--MSKAEAAEAFNQVDTNGNGELSLDELL 159 Score = 43.8 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 49/121 (40%), Gaps = 19/121 (15%) Query: 29 QKQEVREAFD-LFD-------SDGSGTIDVKELKVAMRALGFEPRKEEMKK--------M 72 + Q ++ AF LFD G++ ++ L FE + + + Sbjct: 48 EVQTLKNAFGGLFDYLAKEAGVGSDGSLTEEQFIRVTENLIFEQGEASFNRVLGPVVKGI 107 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + DK A G+I+ ++F A +T A +K E +AF D + G++S L + Sbjct: 108 VGMCDKNADGQINADEFAAWLT---ALGMSKAEAAEAFNQVDTNGNGELSLDELLTAVRD 164 Query: 133 L 133 Sbjct: 165 F 165 Score = 34.5 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 27/69 (39%), Gaps = 1/69 (1%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 + K+ + L K E EAF+ D++G+G + + EL A+R Sbjct: 107 IVGMCDKNADGQINADEFAAWLTALGM-SKAEAAEAFNQVDTNGNGELSLDELLTAVRDF 165 Query: 61 GFEPRKEEM 69 F E+ Sbjct: 166 HFGRLDVEL 174 >5ZGM-A nrPDB Length = 110 Score = 56.5 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 44/91 (48%), Gaps = 6/91 (6%) Query: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESL 137 G + F ++ + ++ ++ + F + D D++G I + LK V G L Sbjct: 22 PGTFDYKRFFQLVG---LKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDL 78 Query: 138 TDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 +D E + ++ D D DG++ +EF K++ + Sbjct: 79 SDTETKALLAAGDSDHDGKIGADEFAKMVAQ 109 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 4/88 (4%) Query: 11 ASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL---GFEPRKE 67 + YKR L + +V+E F++ D D SG I+ +ELK ++ G + Sbjct: 23 GTFDYKRFF-QLVGLKGKSEAQVKEVFEILDKDQSGFIEEEELKSVLKGFSAHGRDLSDT 81 Query: 68 EMKKMISEVDKEATGKISFNDFLAVMTQ 95 E K +++ D + GKI ++F ++ Q Sbjct: 82 ETKALLAAGDSDHDGKIGADEFAKMVAQ 109 >2M7L-A nrPDB Length = 144 Score = 56.5 bits (135), Expect = 6e-09, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 69/151 (45%), Gaps = 15/151 (9%) Query: 20 GPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGF------EPRKEEMKKMI 73 G +T +Q QE +++FD FD + G +D E + + ++G + + Sbjct: 1 GSSSGVTAEQMQEFKQSFDAFDGNHDGILDKLEFRSCLSSMGLIDIDFTGGEDAQYDAIY 60 Query: 74 SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL 133 + V K G +SF++++ M +K E + E++ + F + I+ ++++ Sbjct: 61 NNVTKGENG-VSFDNYVQYMKEKNDENPSPEQLNEIFSTIAAGKD-SITETDMQKA---- 114 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 ++ E+++ + + GDG + ++K Sbjct: 115 --GMSAEQIEYVKANLPQKGDGY-DYAAWVK 142 >2M1U-A nrPDB Length = 93 Score = 56.1 bits (134), Expect = 7e-09, Method: Composition-based stats. Identities = 17/79 (21%), Positives = 40/79 (50%), Gaps = 1/79 (1%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 ++ + D K ++++AF FD D G +S + + + + G +T+ E+ E + AD Sbjct: 14 LVPRGSHMSDEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEAADP 72 Query: 152 DGDGEVNEEEFLKIMKKTN 170 + G ++ + F ++ + Sbjct: 73 NNTGFIDYKAFAAMLYSVD 91 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 20/66 (30%), Positives = 33/66 (50%), Gaps = 1/66 (1%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 D+K ++ EAF FD D G + V+E + +R G + E+ + D TG I + Sbjct: 23 DEKTQLIEAFYNFDGDYDGFVSVEEFRGIIRD-GLPMTEAEITEFFEAADPNNTGFIDYK 81 Query: 88 DFLAVM 93 F A++ Sbjct: 82 AFAAML 87 >2D58-A nrPDB Length = 107 Score = 56.1 bits (134), Expect = 8e-09, Method: Composition-based stats. Identities = 23/68 (33%), Positives = 36/68 (52%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL 90 + +E + FD +G+G ID+ LK + LG E+KK+I EV + S+ DFL Sbjct: 32 EGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSGSGETFSYPDFL 91 Query: 91 AVMTQKMA 98 +M K + Sbjct: 92 RMMLGKRS 99 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + E + + FD + G I +LKR+ +LG T EL+++I E Sbjct: 21 YSSDEDLPSKLEGFKEKYMEFDLNGNGDIDIMSLKRMLEKLGVPKTHLELKKLIGEVSSG 80 Query: 153 GDGEVNEEEFLKIM 166 + +FL++M Sbjct: 81 SGETFSYPDFLRMM 94 >1NP8-A nrPDB Length = 159 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 45/114 (39%), Gaps = 13/114 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + ++ + + Q + FD+D SGTI EL A A Sbjct: 59 MVAVMDSDTTGKLGFEEFKYLWNNIKKWQG-----IYKRFDTDRSGTIGSNELPGAFEAA 113 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFD 114 GF + + MI + TG + F++F++ + + + + +AFR D Sbjct: 114 GFHL-NQHIYSMIIRRYSDETGNMDFDNFISCLVRL-------DAMFRAFRSLD 159 Score = 45.7 bits (107), Expect = 9e-06, Method: Composition-based stats. Identities = 25/151 (16%), Positives = 57/151 (37%), Gaps = 17/151 (11%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAM-RALGFEPRK-------EEMKKMISEVDKE 79 +++++ R+ F D + EL + + + P + + M++ +D + Sbjct: 8 EEERQFRKLFVQLAGD-DMEVSATELMNILNKVVTRHPDLKTDGFGIDTCRSMVAVMDSD 66 Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD 139 TGK+ F +F + ++ ++ FD D +G I L G L Sbjct: 67 TTGKLGFEEF-------KYLWNNIKKWQGIYKRFDTDRSGTIGSNELPGAFEAAGFHLNQ 119 Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 +I D G ++ + F+ + + + Sbjct: 120 HIYSMIIRRY-SDETGNMDFDNFISCLVRLD 149 >1IJ5-A nrPDB Length = 323 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 66/165 (40%), Gaps = 8/165 (4%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 +AS + ++ Y R KP L+E+ +R+ F GSG ++LK + Sbjct: 92 LASLLKDLEDDASGYNRLRPSKPMLSEEDTNILRQLFLSSAVSGSGKFSFQDLKQVLAKY 151 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 + +KK+ V+ + G++S+ +AV ++ FR D + G Sbjct: 152 ADTIPEGPLKKLFVMVENDTKGRMSYITLVAVANDLA-------ALVADFRKIDTNSNGT 204 Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 +S K + LG + + AD D +V E++ + Sbjct: 205 LSRKEFREHFVRLGFDKKSVQ-DALFRYADEDESDDVGFSEYVHL 248 Score = 49.2 bits (116), Expect = 8e-07, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 62/131 (47%), Gaps = 9/131 (6%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQK 96 F D++ +GT+ KE + LGF+ + + + D++ + + F++++ + Sbjct: 194 FRKIDTNSNGTLSRKEFREHFVRLGFDKKSVQ-DALFRYADEDESDDVGFSEYVHLGLCL 252 Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD-EELQEMIDEADRDGDG 155 + + IL AF FD +G++S + +++V + + ++ + D D Sbjct: 253 LVLR-----ILYAFADFDK--SGQLSKEEVQKVLEDAHIPESARKKFEHQFSVVDVDDSK 305 Query: 156 EVNEEEFLKIM 166 ++ +EF+ ++ Sbjct: 306 SLSYQEFVMLV 316 Score = 36.1 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 22/102 (21%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 ++++ +GK SF D V+ + A+ + + K F + ++D G++S+ L Sbjct: 124 LRQLFLSSAVSGSGKFSFQDLKQVLAKY-ADTIPEGPLKKLFVMVENDTKGRMSYITLVA 182 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 VAN+L + D + D + +G ++ +EF + + Sbjct: 183 VANDLAALVAD------FRKIDTNSNGTLSRKEFREHFVRLG 218 Score = 29.5 bits (65), Expect = 0.78, Method: Composition-based stats. Identities = 14/94 (14%), Positives = 45/94 (47%), Gaps = 5/94 (5%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN 125 K+ + ++ +++ +A+G +++++ + + F +GK SF++ Sbjct: 89 KQRLASLLKDLEDDASGYNRLRPSKPMLSEEDTNI-----LRQLFLSSAVSGSGKFSFQD 143 Query: 126 LKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 LK+V + +++ + L+++ + D G ++ Sbjct: 144 LKQVLAKYADTIPEGPLKKLFVMVENDTKGRMSY 177 >5PAL-A nrPDB Length = 109 Score = 55.7 bits (133), Expect = 1e-08, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 49/108 (45%), Gaps = 8/108 (7%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + +++ K IS G + F ++ + T ++ + F + D D++G I Sbjct: 6 LKADDINKAISAFK--DPGTFDYKRFFHLVG---LKGKTDAQVKEVFEILDKDQSGFIEE 60 Query: 124 KNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 + LK V G L D E + ++ D D DG++ +EF K++ + Sbjct: 61 EELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGADEFAKMVAQ 108 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 20/68 (29%), Positives = 37/68 (54%), Gaps = 3/68 (4%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRAL---GFEPRKEEMKKMISEVDKEATGKISFN 87 +V+E F++ D D SG I+ +ELK ++ G + E K +++ D + GKI + Sbjct: 41 AQVKEVFEILDKDQSGFIEEEELKGVLKGFSAHGRDLNDTETKALLAAGDSDHDGKIGAD 100 Query: 88 DFLAVMTQ 95 +F ++ Q Sbjct: 101 EFAKMVAQ 108 Score = 26.8 bits (58), Expect = 4.3, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 36/77 (46%), Gaps = 4/77 (5%) Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDG 155 M + ++I KA F + G +K + G+ TD +++E+ + D+D G Sbjct: 1 PMTKVLKADDINKAISAF--KDPGTFDYKRFFHLVGLKGK--TDAQVKEVFEILDKDQSG 56 Query: 156 EVNEEEFLKIMKKTNLY 172 + EEE ++K + + Sbjct: 57 FIEEEELKGVLKGFSAH 73 >1KFU-L nrPDB Length = 699 Score = 55.0 bits (131), Expect = 2e-08, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 47/124 (37%), Gaps = 13/124 (10%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M K + Q+ ++ + D D SGT++ E++ A+ Sbjct: 579 MVDMLDSDGSGKLGLKEFYILWTK-----IQKYQKIYREIDVDRSGTMNSYEMRKALEEA 633 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF+ + + +++ + I F++F+ + + E + K F+ D + TG Sbjct: 634 GFKMPCQLHQVIVARFADDQL-IIDFDNFVRCLVRL-------ETLFKIFKQLDPENTGT 685 Query: 121 ISFK 124 I Sbjct: 686 IELD 689 Score = 50.0 bits (118), Expect = 5e-07, Method: Composition-based stats. Identities = 28/155 (18%), Positives = 64/155 (41%), Gaps = 18/155 (11%) Query: 24 ELTEDQKQE-VREAFDLFDSDGSGTIDVKELKVAMRAL--------GFEPRKEEMKKMIS 74 +++ED + VR F + I EL+ +R + E K M+ Sbjct: 523 DISEDDIDDGVRRLFAQL-AGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVD 581 Query: 75 EVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG 134 +D + +GK+ +F + T+ ++ K +R D D +G ++ +++ E G Sbjct: 582 MLDSDGSGKLGLKEFYILWTKI-------QKYQKIYREIDVDRSGTMNSYEMRKALEEAG 634 Query: 135 ESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 + +L ++I D ++ + F++ + + Sbjct: 635 FKM-PCQLHQVIVARFADDQLIIDFDNFVRCLVRL 668 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 28/142 (19%), Positives = 47/142 (33%), Gaps = 24/142 (16%) Query: 53 LKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRL 112 L+ + P E + S + G F A D E L+ F + Sbjct: 467 LREVLNRFKLPPG--EYILVPSTFEPNKDGDFCIRVFSEKKADYQAVDDEIEANLEEFDI 524 Query: 113 FDDD--------------ETGKISFKNLKRVANEL--------GESLTDEELQEMIDEAD 150 +DD E +IS L+ + + + + E + M+D D Sbjct: 525 SEDDIDDGVRRLFAQLAGEDAEISAFELQTILRRVLAKRQDIKSDGFSIETCKIMVDMLD 584 Query: 151 RDGDGEVNEEEFLKIMKKTNLY 172 DG G++ +EF + K Y Sbjct: 585 SDGSGKLGLKEFYILWTKIQKY 606 >3DF0-A nrPDB Length = 714 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 48/124 (38%), Gaps = 13/124 (10%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 M + K + Q+ ++ + D D SGT++ E++ A+ Sbjct: 580 MVDMLDEDGSGKLGLKEFYILWTK-----IQKYQKIYREIDVDRSGTMNSYEMRKALEEA 634 Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 GF+ + + +++ + I F++F+ + + E + K F+ D + TG Sbjct: 635 GFKLPCQLHQVIVARF-ADDELIIDFDNFVRCLVRL-------EILFKIFKQLDPENTGT 686 Query: 121 ISFK 124 I Sbjct: 687 IQLD 690 Score = 50.3 bits (119), Expect = 4e-07, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 57/135 (42%), Gaps = 16/135 (11%) Query: 45 SGTIDVKELKVAMRAL--------GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQK 96 I EL+ +R + E K M+ +D++ +GK+ +F + T+ Sbjct: 545 DAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSGKLGLKEFYILWTKI 604 Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGE 156 ++ K +R D D +G ++ +++ E G L +L ++I D + Sbjct: 605 -------QKYQKIYREIDVDRSGTMNSYEMRKALEEAGFKL-PCQLHQVIVARFADDELI 656 Query: 157 VNEEEFLKIMKKTNL 171 ++ + F++ + + + Sbjct: 657 IDFDNFVRCLVRLEI 671 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 16/77 (20%), Positives = 30/77 (38%), Gaps = 9/77 (11%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANEL--------GESLTDEELQEMIDEADRDGDG 155 + + F E +IS L+ + + + + E + M+D D DG G Sbjct: 532 DGFRRLFAQLAG-EDAEISAFELQTILRRVLAKREDIKSDGFSIETCKIMVDMLDEDGSG 590 Query: 156 EVNEEEFLKIMKKTNLY 172 ++ +EF + K Y Sbjct: 591 KLGLKEFYILWTKIQKY 607 >6EPA-A nrPDB Length = 187 Score = 54.6 bits (130), Expect = 2e-08, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 69/172 (40%), Gaps = 17/172 (9%) Query: 6 RKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRALGFEP 64 +K++ ++ TE + ++ + F D +G + + + + Sbjct: 3 KKNSKLKQDTIDRLTTDTYFTEKEIRQWHKGFL---KDCPNGLLTEQGFIKIYKQFFPDG 59 Query: 65 RKEEMKKM-ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + + D+ G I F +F+ ++ + + E++ AFRL+D D G I+ Sbjct: 60 DPSKFASLVFRVFDENNDGAIEFEEFIRALS-ITSRGNLDEKLHWAFRLYDVDNDGYITR 118 Query: 124 KNLKRV----ANELGESLTDEE-------LQEMIDEADRDGDGEVNEEEFLK 164 + + + +G+ E+ + ++ D+ D++ D + EEF + Sbjct: 119 EEMYNIVDAIYQMVGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEFRE 170 Score = 53.4 bits (127), Expect = 5e-08, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 44/103 (42%), Gaps = 1/103 (0%) Query: 65 RKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 ++E+++ K+ G ++ F+ + Q + D + FR+FD++ G I F Sbjct: 23 TEKEIRQWHKGFLKDCPNGLLTEQGFIKIYKQFFPDGDPSKFASLVFRVFDENNDGAIEF 82 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + R + DE+L D D DG + EE I+ Sbjct: 83 EEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIV 125 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 18/97 (18%), Positives = 42/97 (43%), Gaps = 12/97 (12%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQE-VREAFDLFDSDGSGTIDVKEL----KVAMRA 59 F ++N + ++ + + E + AF L+D D G I +E+ + Sbjct: 72 FDENNDGAIEFEEFIRALSITSRGNLDEKLHWAFRLYDVDNDGYITREEMYNIVDAIYQM 131 Query: 60 LGFEPRKEE-------MKKMISEVDKEATGKISFNDF 89 +G +P+ E+ + K+ ++DK +++ +F Sbjct: 132 VGQQPQTEDENTPQKRVDKIFDQMDKNHDDRLTLEEF 168 >3CS1-A nrPDB Length = 219 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 28/176 (15%), Positives = 55/176 (31%), Gaps = 20/176 (11%) Query: 6 RKSNVASTSYKRKVGPKPELTEDQKQEVR----EAFDLFDSDGSGTIDVKEL-KVAMRAL 60 + A + + + ++ E + E F FD + +G + E+ + L Sbjct: 19 KDGKKAKDRKEAWERIRQAIPREKTAEAKQRRIELFKKFDKNETGKLCYDEVYSGCLEVL 78 Query: 61 GFEPRKEEMKKMISEV---------DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFR 111 + ++ + E G F +FL + E+ F Sbjct: 79 KLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEFLE-FRLMLCYIYDFFELTVMFD 137 Query: 112 LFDDDETGKISFKNLKRV---ANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 D + + KR G + E+ + E D++G G V +EF Sbjct: 138 EIDASGNMLVDEEEFKRAVPKLEAWGAKV--EDPAALFKELDKNGTGSVTFDEFAA 191 Score = 34.2 bits (77), Expect = 0.029, Method: Composition-based stats. Identities = 33/142 (23%), Positives = 52/142 (36%), Gaps = 13/142 (9%) Query: 41 DSDGSGTIDVKELKVAMRALGFEPRKEEMK----KMISEVDKEATGKISFNDFLAVMTQK 96 D DG D KE +R + E K ++ + DK TGK+ +++ + + Sbjct: 18 DKDGKKAKDRKEAWERIRQAIPREKTAEAKQRRIELFKKFDKNETGKLCYDEVYSGCLEV 77 Query: 97 MAEKDTKEEILKAF-RLFDD--------DETGKISFKNLKRVANELGESLTDEELQEMID 147 + + + R FD + G F L EL M D Sbjct: 78 LKLDEFTSRVRDITKRAFDKSRTLGSKLENKGSEDFVEFLEFRLMLCYIYDFFELTVMFD 137 Query: 148 EADRDGDGEVNEEEFLKIMKKT 169 E D G+ V+EEEF + + K Sbjct: 138 EIDASGNMLVDEEEFKRAVPKL 159 >2LVV-A nrPDB Length = 226 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 61/179 (34%), Gaps = 21/179 (11%) Query: 2 ASTFRKSNVASTSYK-RKVGPKPELTEDQKQEVR----EAFDLFDSDGSGTIDVKE-LKV 55 AS K + K + + D+ E + E F FD++G+G + +E L Sbjct: 17 ASKGGKDGKTTADRKVAWERIRCAIPRDKDAESKSRRIELFKQFDTNGTGKLGFREVLDG 76 Query: 56 AMRALGFEPRKEEMKKMISEV---------DKEATGKISFNDFLAVMTQKMAEKDTKEEI 106 L + + ++ + G+ +FL + E+ Sbjct: 77 CYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEEDLVEFLE-FRLMLCYIYDIFEL 135 Query: 107 LKAFRLFDDDETGKISFKNLKRVA---NELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 F D D + + + K E G +TD + +E D +G G V +EF Sbjct: 136 TVMFDTMDKDGSLLLELQEFKEALPKLKEWGVDITDAT--TVFNEIDTNGSGVVTFDEF 192 Score = 30.7 bits (68), Expect = 0.32, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 36/108 (33%), Gaps = 9/108 (8%) Query: 71 KMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF-RLFDDDET--------GKI 121 ++ + D TGK+ F + L + + + R FD + G+ Sbjct: 55 ELFKQFDTNGTGKLGFREVLDGCYGILKLDEFTTHLPDIVQRAFDKAKDLGNKVKGVGEE 114 Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 L EL M D D+DG + +EF + + K Sbjct: 115 DLVEFLEFRLMLCYIYDIFELTVMFDTMDKDGSLLLELQEFKEALPKL 162 >3PAT-A nrPDB Length = 110 Score = 54.2 bits (129), Expect = 3e-08, Method: Composition-based stats. Identities = 29/106 (27%), Positives = 52/106 (49%), Gaps = 8/106 (7%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 + +++KK + V A G + F A++ + + ++ K F+ D D +G I Sbjct: 7 LKADDIKKALDAVK--AEGSFNHKKFFALVG---LKAMSANDVKKVFKAIDADASGFIEE 61 Query: 124 KNLKRVANEL---GESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + LK V G LTD E + + AD+DGDG++ +EF ++ Sbjct: 62 EELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGIDEFETLV 107 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 36/68 (52%), Gaps = 3/68 (4%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRAL---GFEPRKEEMKKMISEVDKEATGKISFN 87 +V++ F D+D SG I+ +ELK +++ G + E K + DK+ GKI + Sbjct: 42 NDVKKVFKAIDADASGFIEEEELKFVLKSFAADGRDLTDAETKAFLKAADKDGDGKIGID 101 Query: 88 DFLAVMTQ 95 +F ++ + Sbjct: 102 EFETLVHE 109 >1TIZ-A nrPDB Length = 67 Score = 53.8 bits (128), Expect = 3e-08, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 34/63 (53%) Query: 107 LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + F FD ++ GK+S + VA T E++ + +E D DG+GE+N +EF + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSCI 63 Query: 167 KKT 169 +K Sbjct: 64 EKM 66 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 31/62 (50%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 + F+ FD + G + + E + A +E++ K E+D + G+++ ++F + + Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPYFTQEDIVKFFEEIDVDGNGELNADEFTSCI 63 Query: 94 TQ 95 + Sbjct: 64 EK 65 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 1/57 (1%) Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 K++ + DK GK+S ++F V T+E+I+K F D D G+++ Sbjct: 4 KRVFEKFDKNKDGKLSLDEFREVALAFSPY-FTQEDIVKFFEEIDVDGNGELNADEF 59 >1S6C-A nrPDB Length = 183 Score = 53.8 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN 131 + + D TG + F DF+ ++ + E++ F L+D ++ G I+ + + + Sbjct: 61 LFNAFDTTQTGSVKFEDFVTALS-ILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVK 119 Query: 132 ELGESLTD------------EELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + + + + + + D++ DG V +EFL+ ++ + Sbjct: 120 AIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 171 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 1/106 (0%) Query: 63 EPRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 K E++ + E +G ++ F + Q D F FD +TG + Sbjct: 14 NFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSV 73 Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 F++ + L E+L+ + D + DG +N+EE + I+K Sbjct: 74 KFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVK 119 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 16/107 (14%), Positives = 41/107 (38%), Gaps = 11/107 (10%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFL------ 90 F+ FD+ +G++ ++ A+ L E+++ + D G I+ + + Sbjct: 62 FNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 121 Query: 91 -AVMTQKM----AEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 +M + E ++ + F+ D ++ G ++ E Sbjct: 122 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQE 168 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 42/111 (37%), Gaps = 13/111 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQE-VREAFDLFDSDGSGTIDVKEL------ 53 + + F + S ++ V L E +R F+L+D + G I+ +E+ Sbjct: 61 LFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 120 Query: 54 ------KVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMA 98 K L + ++ + ++DK G ++ ++FL + Sbjct: 121 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 171 >4PAL-A nrPDB Length = 108 Score = 53.8 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEMID 147 + + +++ KAF + D D++G I LK S LTD E + + Sbjct: 28 EFFAKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLA 87 Query: 148 EADRDGDGEVNEEEFLKIMK 167 + D+DGDG + +EF ++K Sbjct: 88 DGDKDGDGMIGVDEFAAMIK 107 Score = 44.9 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 36/75 (48%), Gaps = 3/75 (4%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEPRKEEMKKMISEVD 77 K L +V++AF + D D SG I+ ELK+ ++ E K +++ D Sbjct: 31 AKVGLASKSLDDVKKAFYVIDQDKSGFIEEDELKLFLQNFSPSARALTDAETKAFLADGD 90 Query: 78 KEATGKISFNDFLAV 92 K+ G I ++F A+ Sbjct: 91 KDGDGMIGVDEFAAM 105 >1A75-A nrPDB Length = 108 Score = 53.8 bits (128), Expect = 4e-08, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 3/82 (3%) Query: 89 FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLK---RVANELGESLTDEELQEM 145 + A + + ++I KAF D D++G I LK +V +LTD E + Sbjct: 26 YKAFFAKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAETKAF 85 Query: 146 IDEADRDGDGEVNEEEFLKIMK 167 + D DGDG + EE++ ++K Sbjct: 86 LKAGDSDGDGAIGVEEWVALVK 107 Score = 44.9 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 37/85 (43%), Gaps = 4/85 (4%) Query: 12 STSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELK---VAMRALGFEPRKEE 68 S SYK K L+ ++++AF D D SG I+ ELK +A E Sbjct: 23 SFSYKAFF-AKCGLSGKSADDIKKAFVFIDQDKSGFIEEDELKLFLQVFKAGARALTDAE 81 Query: 69 MKKMISEVDKEATGKISFNDFLAVM 93 K + D + G I +++A++ Sbjct: 82 TKAFLKAGDSDGDGAIGVEEWVALV 106 >1SL8-A nrPDB Length = 191 Score = 53.0 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 24/158 (15%), Positives = 58/158 (36%), Gaps = 20/158 (12%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELK-----VAMRALGFEPRKEE-----MKKMISEV 76 + F+ D + +G I + E+ + + LG P + + ++ Sbjct: 12 PKWIGRHKHMFNFLDVNHNGRISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGA 71 Query: 77 DKEATGKISFNDFLAV---MTQKMAEKDTKEEIL-------KAFRLFDDDETGKISFKNL 126 + + + +++ + + ++ +K +I F + D D+ G IS Sbjct: 72 GMKYGVETEWPEYIEGWKRLASEELKRYSKNQITLIRLWGDALFDIIDKDQNGAISLDEW 131 Query: 127 KRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 K G + E+ +E D D G+++ +E + Sbjct: 132 KAYTKSAGIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >1S1E-A nrPDB Length = 224 Score = 53.0 bits (126), Expect = 6e-08, Method: Composition-based stats. Identities = 19/112 (16%), Positives = 48/112 (42%), Gaps = 13/112 (11%) Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN 131 + + D TG + F DF+ ++ + E++ F L+D ++ G I+ + + + Sbjct: 94 LFNAFDTTQTGSVKFEDFVTALS-ILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVK 152 Query: 132 ELGESLTD------------EELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 + + + + + + D++ DG V +EFL+ ++ + Sbjct: 153 AIYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 204 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 24/106 (22%), Positives = 44/106 (41%), Gaps = 1/106 (0%) Query: 63 EPRKEEMKKMISEVDKEA-TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 K E++ + E +G ++ F + Q D F FD +TG + Sbjct: 47 NFTKRELQVLYRGFKNECPSGVVNEETFKQIYAQFFPHGDASTYAHYLFNAFDTTQTGSV 106 Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 F++ + L E+L+ + D + DG +N+EE + I+K Sbjct: 107 KFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVK 152 Score = 44.9 bits (105), Expect = 2e-05, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 41/107 (38%), Gaps = 11/107 (10%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT-- 94 F+ FD+ +G++ ++ A+ L E+++ + D G I+ + + ++ Sbjct: 95 FNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKAI 154 Query: 95 ---------QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + E ++ + F+ D ++ G ++ E Sbjct: 155 YDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQE 201 Score = 39.9 bits (92), Expect = 5e-04, Method: Composition-based stats. Identities = 19/111 (17%), Positives = 42/111 (37%), Gaps = 13/111 (11%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQE-VREAFDLFDSDGSGTIDVKEL------ 53 + + F + S ++ V L E +R F+L+D + G I+ +E+ Sbjct: 94 LFNAFDTTQTGSVKFEDFVTALSILLRGTVHEKLRWTFNLYDINKDGYINKEEMMDIVKA 153 Query: 54 ------KVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMA 98 K L + ++ + ++DK G ++ ++FL + Sbjct: 154 IYDMMGKYTYPVLKEDTPRQHVDVFFQKMDKNKDGIVTLDEFLESCQEDDN 204 >5JOJ-A nrPDB Length = 97 Score = 53.0 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 6/74 (8%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKE 79 +++++ E+REAF D+DG+G I EL +A G+ R+ + +++ D + Sbjct: 6 VSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREIT-ENLMATGDLD 64 Query: 80 ATGKISFNDFLAVM 93 G+ISF++F+ + Sbjct: 65 QDGRISFDEFIKIF 78 Score = 48.8 bits (115), Expect = 1e-06, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLT----DEELQEMIDE 148 M + + E+ +AF D D G ISF L + L E + ++ Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60 Query: 149 ADRDGDGEVNEEEFLKI 165 D D DG ++ +EF+KI Sbjct: 61 GDLDQDGRISFDEFIKI 77 Score = 32.6 bits (73), Expect = 0.093, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 37/85 (43%), Gaps = 3/85 (3%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEK---DTKEEILKAFRLFDDDETGKISF 123 E+++ ++VD + G ISFN+ + +E D D+ G+ISF Sbjct: 12 MELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 124 KNLKRVANELGESLTDEELQEMIDE 148 ++ + L + + ++ I++ Sbjct: 72 DEFIKIFHGLKSTDVAKTFRKAINK 96 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 EL+E + D DG+G ++ E + K L Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACL 43 >2KQY-A nrPDB Length = 108 Score = 53.0 bits (126), Expect = 7e-08, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 3/82 (3%) Query: 89 FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEM 145 + + + T ++I K F + D D++G I + L+ S LT E + Sbjct: 26 YKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNFSSSARVLTSAETKAF 85 Query: 146 IDEADRDGDGEVNEEEFLKIMK 167 + D DGDG++ EEF ++K Sbjct: 86 LAAGDTDGDGKIGVEEFQSLVK 107 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 40/96 (41%), Gaps = 3/96 (3%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 + S A + + L+ ++++ F + D D SG I+ +EL++ ++ Sbjct: 11 IESALSSCQAADSFNYKSFFSTVGLSSKTPDQIKKVFGILDQDKSGFIEEEELQLFLKNF 70 Query: 61 GFE---PRKEEMKKMISEVDKEATGKISFNDFLAVM 93 E K ++ D + GKI +F +++ Sbjct: 71 SSSARVLTSAETKAFLAAGDTDGDGKIGVEEFQSLV 106 Score = 27.2 bits (59), Expect = 4.0, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 3/57 (5%) Query: 3 STFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 S F + K LT + + A D+DG G I V+E + ++A Sbjct: 55 SGFIEEEELQLFLKNFSSSARVLTSAETKAFLAA---GDTDGDGKIGVEEFQSLVKA 108 >5JOL-A nrPDB Length = 82 Score = 52.7 bits (125), Expect = 9e-08, Method: Composition-based stats. Identities = 21/74 (28%), Positives = 42/74 (56%), Gaps = 6/74 (8%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKE 79 +++++ E+REAF D+DG+G I EL +A G+ R+ + +++ D + Sbjct: 6 VSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREIT-ENLMATGDLD 64 Query: 80 ATGKISFNDFLAVM 93 G+ISF++F+ + Sbjct: 65 QDGRISFDEFIKIF 78 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 33/77 (42%), Gaps = 4/77 (5%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLT----DEELQEMIDE 148 M + + E+ +AF D D G ISF L + L E + ++ Sbjct: 1 MARGSVSDEEMMELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMAT 60 Query: 149 ADRDGDGEVNEEEFLKI 165 D D DG ++ +EF+KI Sbjct: 61 GDLDQDGRISFDEFIKI 77 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%), Gaps = 3/70 (4%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEK---DTKEEILKAFRLFDDDETGKISF 123 E+++ ++VD + G ISFN+ + +E D D+ G+ISF Sbjct: 12 MELREAFAKVDTDGNGYISFNELNDLFKAACLPLPGYRVREITENLMATGDLDQDGRISF 71 Query: 124 KNLKRVANEL 133 ++ + L Sbjct: 72 DEFIKIFHGL 81 Score = 28.4 bits (62), Expect = 1.5, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 141 ELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 EL+E + D DG+G ++ E + K L Sbjct: 13 ELREAFAKVDTDGNGYISFNELNDLFKAACL 43 >5VE9-A nrPDB Length = 91 Score = 52.3 bits (124), Expect = 1e-07, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 33/84 (39%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEM 69 +A+ + +K V + F D D G I +E + A F K EM Sbjct: 6 MANFDFDVWRKKYMRWMNHKKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEM 65 Query: 70 KKMISEVDKEATGKISFNDFLAVM 93 + D++ G I + +F+A + Sbjct: 66 TAVADIFDRDGDGYIDYYEFVAAL 89 Score = 50.0 bits (118), Expect = 6e-07, Method: Composition-based stats. Identities = 19/63 (30%), Positives = 29/63 (46%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 K ++ FR D D+ GKI+ + T E+ + D DRDGDG ++ E Sbjct: 25 KKSRVMDFFRRIDKDQDGKITRQEFIDGILASKFPTTKLEMTAVADIFDRDGDGYIDYYE 84 Query: 162 FLK 164 F+ Sbjct: 85 FVA 87 Score = 35.7 bits (81), Expect = 0.012, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 26/66 (39%), Gaps = 1/66 (1%) Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +K + +DK+ GKI+ +F+ + TK E+ +FD D G I + Sbjct: 25 KKSRVMDFFRRIDKDQDGKITRQEFIDGIL-ASKFPTTKLEMTAVADIFDRDGDGYIDYY 83 Query: 125 NLKRVA 130 Sbjct: 84 EFVAAL 89 >2HPS-A nrPDB Length = 186 Score = 51.9 bits (123), Expect = 1e-07, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 65/163 (39%), Gaps = 19/163 (11%) Query: 23 PELTEDQKQ----EVREAFDLFDSDGSGTIDVK--ELKVA----MRALGFEPRKEEMKKM 72 PE+TE ++ +++ D G G I + EL + L E +E ++ Sbjct: 2 PEITESERAYHLRKMKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEF 61 Query: 73 ISEVDKEATGK---ISFNDFLAVMTQKMAEKDTKEEILK------AFRLFDDDETGKISF 123 + D+ IS + T + + +E+ + + D D+ G +S Sbjct: 62 LRVADQLGLAPGVRISVEEAAVNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSL 121 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 K +G LTD++ + D + +G+++ +EFL + Sbjct: 122 PEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTV 164 Score = 43.0 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 30/60 (50%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQK 96 +D D+D G + + E K ++A+G + ++ + +D G+IS ++FL + Sbjct: 108 YDCIDTDKDGYVSLPEFKAFLQAVGPDLTDDKAITCFNTLDFNKNGQISRDEFLVTVNDF 167 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 42/114 (36%), Gaps = 15/114 (13%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQK--------MAEKDTKEEILKAFRLFDDDETGK 120 MK + VD G IS D+ + + ++T++E L+ + Sbjct: 16 MKTRMQRVDVTGDGFISREDYELIAVRIAKIAKLSAEKAEETRQEFLRVADQLGLAPGVR 75 Query: 121 ISFKNLK-----RVANELGESLTDEELQEMI--DEADRDGDGEVNEEEFLKIMK 167 IS + + GE +Q +I D D D DG V+ EF ++ Sbjct: 76 ISVEEAAVNATDSLLKMKGEEKAMAVIQSLIMYDCIDTDKDGYVSLPEFKAFLQ 129 >1UHK-A nrPDB Length = 191 Score = 51.9 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 21/151 (13%), Positives = 54/151 (35%), Gaps = 20/151 (13%) Query: 34 REAFDLFDSDGSGTIDVKELK-----VAMRALGFEPRKEE-----MKKMISEVDKEATGK 83 + F+ D + +G I + E+ + + LG P + + ++ + + Sbjct: 19 KHMFNFLDVNHNGKISLDEMVYKASDIVINNLGATPEQAKRHKDAVEAFFGGAGMKYGVE 78 Query: 84 ISFNDFLA-----VMTQKMAEKDTKEEILKA-----FRLFDDDETGKISFKNLKRVANEL 133 + ++ + + +++ F + D D+ G I+ K Sbjct: 79 TDWPAYIEGWKKLATDELEKYAKNEPTLIRIWGDALFDIVDKDQNGAITLDEWKAYTKAA 138 Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 G + E+ +E D D G+++ +E + Sbjct: 139 GIIQSSEDCEETFRVCDIDESGQLDVDEMTR 169 >1BU3-A nrPDB Length = 109 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 37/82 (45%), Gaps = 3/82 (3%) Query: 89 FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEM 145 + A + + ++I KAF + D D++G I LK LTD E + Sbjct: 27 YKAFFAKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAETKAF 86 Query: 146 IDEADRDGDGEVNEEEFLKIMK 167 + D DGDG + +E+ ++K Sbjct: 87 LKAGDSDGDGAIGVDEWAALVK 108 Score = 45.7 bits (107), Expect = 9e-06, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 12 STSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEPRKEE 68 S +YK K LT ++++AF + D D SG I+ ELK+ ++ E Sbjct: 24 SFNYKAFF-AKVGLTAKSADDIKKAFFVIDQDKSGFIEEDELKLFLQVFSAGARALTDAE 82 Query: 69 MKKMISEVDKEATGKISFND 88 K + D + G I ++ Sbjct: 83 TKAFLKAGDSDGDGAIGVDE 102 >5CPV-A nrPDB Length = 109 Score = 51.5 bits (122), Expect = 2e-07, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQEMID 147 A + + +++ KAF + D D++G I LK +LTD E + + Sbjct: 29 AFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFLK 88 Query: 148 EADRDGDGEVNEEEFLKIMK 167 D DGDG++ +EF ++K Sbjct: 89 AGDSDGDGKIGVDEFTALVK 108 Score = 46.1 bits (108), Expect = 9e-06, Method: Composition-based stats. Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 3/80 (3%) Query: 17 RKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFE---PRKEEMKKMI 73 + K LT +V++AF + D D SG I+ ELK+ ++ + E K + Sbjct: 28 KAFFAKVGLTSKSADDVKKAFAIIDQDKSGFIEEDELKLFLQNFKADARALTDGETKTFL 87 Query: 74 SEVDKEATGKISFNDFLAVM 93 D + GKI ++F A++ Sbjct: 88 KAGDSDGDGKIGVDEFTALV 107 >4NQG-A nrPDB Length = 197 Score = 51.1 bits (121), Expect = 2e-07, Method: Composition-based stats. Identities = 21/160 (13%), Positives = 53/160 (33%), Gaps = 24/160 (15%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKV-----AMRALGFEPRKEE-------MKKMIS 74 + F+ D + +G I++ E+ + LG +E+ ++ Sbjct: 17 PKWIARHKHMFNFLDINSNGQINLNEMVHKASNIICKKLGA--TEEQTRRHQKCVEDFFG 74 Query: 75 EVDKEATGKISFNDFLAVMTQKMAEKDTKEEI----------LKAFRLFDDDETGKISFK 124 E ++ +++ + + + F + D D G +S Sbjct: 75 GAGLEYDKDTTWPEYIEGWKRLAKTELERHSKNRVTLIRLWGDALFDIIDKDGNGSVSLD 134 Query: 125 NLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + + G + + + D DGDG+++ +E + Sbjct: 135 EWIQYTHCAGIQQSRGQCEATFAHCDLDGDGKLDVDEMTR 174 >2KYF-A nrPDB Length = 108 Score = 50.7 bits (120), Expect = 3e-07, Method: Composition-based stats. Identities = 21/71 (29%), Positives = 37/71 (52%), Gaps = 3/71 (4%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEMIDEADRDGDGE 156 K + ++ + FR+ D+D++G I LK LT E + + AD DGDG+ Sbjct: 37 KKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGK 96 Query: 157 VNEEEFLKIMK 167 + EEF ++++ Sbjct: 97 IGAEEFQEMVQ 107 Score = 45.3 bits (106), Expect = 1e-05, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 41/97 (42%), Gaps = 3/97 (3%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 +A+ R + +K +++ +++E F + D+D SG I+ ELK ++ Sbjct: 11 IAAALRDCQAPDSFSPKKFFQISGMSKKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRF 70 Query: 61 ---GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 E K ++ D + GKI +F ++ Sbjct: 71 ESGARVLTASETKTFLAAADHDGDGKIGAEEFQEMVQ 107 Score = 29.2 bits (64), Expect = 1.1, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 27/72 (37%), Gaps = 2/72 (2%) Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMA--EKDTKEEILKAFRLFDDDETGK 120 + ++K++ +D + +G I ++ + + + T E D D GK Sbjct: 37 KKSSSQLKEIFRILDNDQSGFIEEDELKYFLQRFESGARVLTASETKTFLAAADHDGDGK 96 Query: 121 ISFKNLKRVANE 132 I + + + Sbjct: 97 IGAEEFQEMVQS 108 >1RTP-1 nrPDB Length = 109 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 49/109 (44%), Gaps = 8/109 (7%) Query: 64 PRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 E++KK I A F ++ +K + +++ K F + D D++G I Sbjct: 6 LSAEDIKKAIGAF--TAADSFDHKKFFQMVG---LKKKSADDVKKVFHILDKDKSGFIEE 60 Query: 124 KNLKRVANELGES---LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 L + L+ +E + ++ D+DGDG++ EEF ++ ++ Sbjct: 61 DELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVEEFSTLVAES 109 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 36/74 (48%), Gaps = 3/74 (4%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEPRKEEMKKMISEVDKEAT 81 L + +V++ F + D D SG I+ EL ++ + +E K +++ DK+ Sbjct: 35 LKKKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGD 94 Query: 82 GKISFNDFLAVMTQ 95 GKI +F ++ + Sbjct: 95 GKIGVEEFSTLVAE 108 >5ZH6-A nrPDB Length = 107 Score = 49.6 bits (117), Expect = 7e-07, Method: Composition-based stats. Identities = 20/98 (20%), Positives = 36/98 (36%), Gaps = 6/98 (6%) Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 I++ + G + F + + K F + D D +G I LK Sbjct: 12 IAKALAQCAGSFNHKTF---FVTSGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQN 68 Query: 133 LGES---LTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + L + E + D D DG++ +EF ++K Sbjct: 69 FSATARELDETETNAFLAAGDSDHDGKIGVDEFKAMVK 106 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 38/89 (42%), Gaps = 3/89 (3%) Query: 8 SNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELK---VAMRALGFEP 64 + A + + LT + + FD+ D D SG I+V ELK A E Sbjct: 17 AQCAGSFNHKTFFVTSGLTNKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATAREL 76 Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVM 93 + E ++ D + GKI ++F A++ Sbjct: 77 DETETNAFLAAGDSDHDGKIGVDEFKAMV 105 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 17/74 (22%), Positives = 27/74 (36%), Gaps = 6/74 (8%) Query: 63 EPRKEEMKKMISEVDKEATGKISFND---FLAVMTQKMAEKDTKEEILKAFRLF-DDDET 118 + K+ +D++ +G I ++ FL + E D E AF D D Sbjct: 36 NKSDANLAKVFDILDQDRSGFIEVDELKLFLQNFSATARELDETET--NAFLAAGDSDHD 93 Query: 119 GKISFKNLKRVANE 132 GKI K + Sbjct: 94 GKIGVDEFKAMVKA 107 >1RK9-A nrPDB Length = 110 Score = 49.2 bits (116), Expect = 9e-07, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 50/106 (47%), Gaps = 8/106 (7%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 E++KK + AT F ++ +K + +++ K F + D D++G I L Sbjct: 10 EDIKKAVGAFS--ATDSFDHKKFFQMVG---LKKKSADDVKKVFHMLDKDKSGFIEEDEL 64 Query: 127 KRVANELGES---LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 + L+ +E + ++ D+DGDG++ +EF ++ ++ Sbjct: 65 GFILKGFSPDARDLSAKETKMLMAAGDKDGDGKIGVDEFSTLVAES 110 Score = 43.0 bits (100), Expect = 6e-05, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 37/74 (50%), Gaps = 3/74 (4%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEPRKEEMKKMISEVDKEAT 81 L + +V++ F + D D SG I+ EL ++ + +E K +++ DK+ Sbjct: 36 LKKKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGD 95 Query: 82 GKISFNDFLAVMTQ 95 GKI ++F ++ + Sbjct: 96 GKIGVDEFSTLVAE 109 Score = 28.0 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 14/66 (21%), Positives = 27/66 (40%), Gaps = 2/66 (3%) Query: 63 EPRKEEMKKMISEVDKEATGKISFND--FLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 + +++KK+ +DK+ +G I ++ F+ A + +E D D GK Sbjct: 38 KKSADDVKKVFHMLDKDKSGFIEEDELGFILKGFSPDARDLSAKETKMLMAAGDKDGDGK 97 Query: 121 ISFKNL 126 I Sbjct: 98 IGVDEF 103 >2MBX-A nrPDB Length = 109 Score = 49.2 bits (116), Expect = 1e-06, Method: Composition-based stats. Identities = 22/91 (24%), Positives = 37/91 (40%), Gaps = 6/91 (6%) Query: 80 ATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES--- 136 A G F T+ + +I K F + D D++ + LK Sbjct: 21 AEGSFDHKAF---FTKVGLAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARA 77 Query: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 L+D E + + D DGDG++ +EF ++K Sbjct: 78 LSDAETKVFLKAGDSDGDGKIGVDEFGAMIK 108 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 36/88 (40%), Gaps = 4/88 (4%) Query: 8 SNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEP 64 S +K K L ++++ F++ D D S ++ ELK+ ++ Sbjct: 20 KAEGSFDHKAFF-TKVGLAAKSPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARAL 78 Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAV 92 E K + D + GKI ++F A+ Sbjct: 79 SDAETKVFLKAGDSDGDGKIGVDEFGAM 106 Score = 27.2 bits (59), Expect = 3.4, Method: Composition-based stats. Identities = 11/71 (15%), Positives = 24/71 (33%), Gaps = 4/71 (5%) Query: 65 RKEEMKKMISEVDKEATGKISFND---FLAVMTQKMAEKDTKEEILKAFRLFDDDETGKI 121 ++KK+ +D++ + + ++ FL + E + D D GKI Sbjct: 40 SPADIKKVFEIIDQDKSDFVEEDELKLFLQNFSAGARALSD-AETKVFLKAGDSDGDGKI 98 Query: 122 SFKNLKRVANE 132 + Sbjct: 99 GVDEFGAMIKA 109 >2NLN-A nrPDB Length = 108 Score = 48.4 bits (114), Expect = 1e-06, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQE 144 + K + ++ FR D+D++G + LK + LT+ E + Sbjct: 25 EPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKFQSDARELTESETKS 84 Query: 145 MIDEADRDGDGEVNEEEFLKIM 166 ++D AD DGDG++ +EF +++ Sbjct: 85 LMDAADNDGDGKIGADEFQEMV 106 Score = 45.7 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 44/96 (45%), Gaps = 3/96 (3%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 +A+ ++ T +K L++ +V++ F D+D SG +D ELK ++ Sbjct: 11 IAAALQECQDPDTFEPQKFFQTSGLSKMSASQVKDIFRFIDNDQSGYLDGDELKYFLQKF 70 Query: 61 G---FEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 E + E K ++ D + GKI ++F ++ Sbjct: 71 QSDARELTESETKSLMDAADNDGDGKIGADEFQEMV 106 >5YPX-A nrPDB Length = 223 Score = 48.4 bits (114), Expect = 1e-06, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 47/127 (37%), Gaps = 15/127 (11%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM-- 93 F FD D I + E + E+M+ + D G IS + ++ Sbjct: 86 VFRAFDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKT 145 Query: 94 ------TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV-------ANELGESLTDE 140 T++ ++ K+ + A + D D ++S K+ K G+ L DE Sbjct: 146 CLVKQPTEEDPDEGIKDLVEIALKKMDHDHDSRLSKKDFKDAVLIEPLLLEAFGKCLPDE 205 Query: 141 ELQEMID 147 + E+ + Sbjct: 206 KSSEIFE 212 Score = 47.3 bits (111), Expect = 4e-06, Method: Composition-based stats. Identities = 25/104 (24%), Positives = 44/104 (42%), Gaps = 2/104 (1%) Query: 65 RKEEMKKMISEVDKEATG-KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISF 123 K E++ +I G K+ N F ++ QK + + + FR FD D IS Sbjct: 42 TKTEVESLIICYKNLLEGLKMDRNLFRDILHQKFNMTEDL-LMDRVFRAFDKDSDSYISL 100 Query: 124 KNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + DE+++ D +GDG ++ EE +++K Sbjct: 101 TEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLK 144 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 36/85 (42%), Gaps = 2/85 (2%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVRE-AFDLFDSDGSGTIDVKELKVAMR-ALGF 62 F K + + S V E E F +FD +G G I +E+ ++ L Sbjct: 90 FDKDSDSYISLTEWVEGLSVFLRGTLDEKMEYTFTVFDLNGDGYISREEMFQMLKTCLVK 149 Query: 63 EPRKEEMKKMISEVDKEATGKISFN 87 +P +E+ + I ++ + A K+ + Sbjct: 150 QPTEEDPDEGIKDLVEIALKKMDHD 174 >1Q80-A nrPDB Length = 174 Score = 48.4 bits (114), Expect = 2e-06, Method: Composition-based stats. Identities = 30/156 (19%), Positives = 53/156 (33%), Gaps = 23/156 (14%) Query: 26 TEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKE------ 79 ++ Q+++ F+ D D G I + + ++ EMK ++V + Sbjct: 1 SDLWVQKMKTYFNRIDFDKDGAITRMDFESMAERF---AKESEMKAEHAKVLMDSLTGVW 57 Query: 80 --------ATGKISFNDFLAVMTQKMAEKDTKEEILKA----FRLFDDDETGKISFKNLK 127 I F+ M + + + K + FR D +E IS Sbjct: 58 DNFLTAVAGGKGIDETTFINSMKEMVKNPEAKSVVEGPLPLFFRAVDTNEDNNISRDEYG 117 Query: 128 RVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 LG L D D + DG ++ EEF+ Sbjct: 118 IFFGMLG--LDKTMAPASFDAIDTNNDGLLSLEEFV 151 >1TTX-A nrPDB Length = 109 Score = 48.0 bits (113), Expect = 2e-06, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 39/82 (47%), Gaps = 3/82 (3%) Query: 88 DFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANEL---GESLTDEELQE 144 + K + ++ FR D+D++G + + LK + LT+ E + Sbjct: 26 EPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKFESGARELTESETKS 85 Query: 145 MIDEADRDGDGEVNEEEFLKIM 166 ++ AD DGDG++ EEF +++ Sbjct: 86 LMAAADNDGDGKIGAEEFQEMV 107 Score = 44.2 bits (103), Expect = 3e-05, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 45/96 (46%), Gaps = 3/96 (3%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRAL 60 +A+ ++ T +K L++ +V++ F D+D SG +D +ELK ++ Sbjct: 12 IAAALQECRDPDTFEPQKFFQTSGLSKMSANQVKDVFRFIDNDQSGYLDEEELKFFLQKF 71 Query: 61 ---GFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 E + E K +++ D + GKI +F ++ Sbjct: 72 ESGARELTESETKSLMAAADNDGDGKIGAEEFQEMV 107 >4P5W-A nrPDB Length = 411 Score = 47.6 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 49/105 (46%), Gaps = 8/105 (7%) Query: 31 QEVREAFDLF---DSDGSGTIDVKEL-KVAMRALGF-EPRKEEMKKMISEVDKEATGKIS 85 E+R F + + +G + + + G +P + ++ + VD+ G IS Sbjct: 37 AELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLIS 96 Query: 86 FNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 F +F+A + A + AF+LFD G+++F+++K+V Sbjct: 97 FQEFVAFESVLCAPDAL---FMVAFQLFDKAGKGEVTFEDVKQVF 138 Score = 46.5 bits (109), Expect = 6e-06, Method: Composition-based stats. Identities = 22/134 (16%), Positives = 51/134 (38%), Gaps = 9/134 (6%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFE---PRKEEMKKMISEVDKEATGKISFNDF 89 AF LFD G G + +++K P + + + KE +++ +F Sbjct: 114 FMVAFQLFDKAGKGEVTFEDVKQVFGQTTIHQHIPFNWDSEFVQLHFGKERKRHLTYAEF 173 Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE-MIDE 148 + + E +AF D+ TG+++ + + + + + ++E ++ Sbjct: 174 TQFLLEIQL-----EHAKQAFVQRDNARTGRVTAIDFRDIMVTIRPHVLTPFVEECLVAA 228 Query: 149 ADRDGDGEVNEEEF 162 A +V+ F Sbjct: 229 AGGTTSHQVSFSYF 242 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 43/111 (38%), Gaps = 6/111 (5%) Query: 66 KEEMKKMI---SEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFR-LFDDDETGKI 121 E++ + + ++K +S NDF+ E + ++ + D + G I Sbjct: 36 PAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQTKDGLI 95 Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 SF+ + L D D+ G GEV E+ ++ +T ++ Sbjct: 96 SFQEFVAFESVLCAP--DALFMVAFQLFDKAGKGEVTFEDVKQVFGQTTIH 144 Score = 31.1 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 30/72 (41%), Gaps = 5/72 (6%) Query: 98 AEKDTKEEILKAFRLFDD-DETGKI---SFKNLKRVANELGES-LTDEELQEMIDEADRD 152 ++ E+ F + ++ G+ + R N GES + ++ + D+ Sbjct: 31 TKRADPAELRTIFLKYASIEKNGEFFMSPNDFVTRYLNIFGESQPNPKTVELLSGVVDQT 90 Query: 153 GDGEVNEEEFLK 164 DG ++ +EF+ Sbjct: 91 KDGLISFQEFVA 102 >1YX7-A nrPDB Length = 83 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 37/78 (47%), Gaps = 6/78 (7%) Query: 30 KQEVREAFDLFDSDGSGTIDVKELKVAM------RALGFEPRKEEMKKMISEVDKEATGK 83 K E+ AF D++G G + EL+ M +AL + KE K+I DK + GK Sbjct: 6 KAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 84 ISFNDFLAVMTQKMAEKD 101 IS +FL + + + Sbjct: 66 ISKEEFLNANAELLCQLK 83 Score = 46.5 bits (109), Expect = 5e-06, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 38/67 (56%), Gaps = 6/67 (8%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGE--SLTDEELQE----MIDEADRDGDGE 156 K E+ AF+ D + G ++ L+ L +L+ ++++E +I AD++ DG+ Sbjct: 6 KAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 157 VNEEEFL 163 +++EEFL Sbjct: 66 ISKEEFL 72 Score = 34.5 bits (78), Expect = 0.024, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 28/69 (40%), Gaps = 5/69 (7%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMT-----QKMAEKDTKEEILKAFRLFDDDETGK 120 K E++ ++D G ++ + M + +++ KE K ++ D + GK Sbjct: 6 KAELEAAFKKLDANGDGYVTALELQTFMVTLDAYKALSKDKVKEASAKLIKMADKNSDGK 65 Query: 121 ISFKNLKRV 129 IS + Sbjct: 66 ISKEEFLNA 74 >4P5X-A nrPDB Length = 315 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 48/131 (36%), Gaps = 9/131 (6%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRAL---GFEPRKEEMKKMISEVDKEATGKISFNDFLAV 92 AF LFD G+G + + +K P + + + +++ +F Sbjct: 98 AFQLFDKSGNGEVTFENVKEIFGQTIIHHHIPFNWDCEFIRLHFGHNRKKHLNYTEFTQF 157 Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE-MIDEADR 151 + + E +AF L D ++G IS + + + + ++E ++ A Sbjct: 158 LQELQL-----EHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSAAGG 212 Query: 152 DGDGEVNEEEF 162 +V+ F Sbjct: 213 SISHQVSFSYF 223 Score = 46.1 bits (108), Expect = 8e-06, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 66/151 (43%), Gaps = 17/151 (11%) Query: 32 EVREAFDLF---DSDGSGTIDVKEL-KVAMRALGFEPRKEEMKKMISEV-DKEATGKISF 86 E+R F + + DG + ++ + + ++ ++++ V D+ G IS+ Sbjct: 19 ELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISY 78 Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ--- 143 +FLA + A + AF+LFD G+++F+N+K + G+++ + Sbjct: 79 QEFLAFESVLCAPDSM---FIVAFQLFDKSGNGEVTFENVKEI---FGQTIIHHHIPFNW 132 Query: 144 --EMIDE-ADRDGDGEVNEEEFLKIMKKTNL 171 E I + +N EF + +++ L Sbjct: 133 DCEFIRLHFGHNRKKHLNYTEFTQFLQELQL 163 Score = 35.7 bits (81), Expect = 0.009, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 51/138 (36%), Gaps = 7/138 (5%) Query: 23 PELTED-QKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 + ++ Q + R+AF L D SG I + M + +++ + A Sbjct: 155 TQFLQELQLEHARQAFALKDKSKSGMISGLDFSDIMVTIRSHMLTPFVEENLVSA---AG 211 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFD-DDETGKISFKNLKRVANELGESLTDE 140 G IS + + + E + K + + +++ + + A G+ +T Sbjct: 212 GSISHQVSFSYFNAFNSLLNNMELVRKIYSTLAGTRKDVEVTKEEFAQSAIRYGQ-VTPL 270 Query: 141 ELQEMIDEADR-DGDGEV 157 E+ + AD + G + Sbjct: 271 EIDILYQLADLYNASGRL 288 Score = 31.9 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 40/101 (39%), Gaps = 3/101 (2%) Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFR-LFDDDETGKISFKNLKRVAN 131 + + + ++ DF+ + ++ +I++ + D + G IS++ + Sbjct: 27 YASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVADQTKDGLISYQEFLAFES 86 Query: 132 ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 L D D+ G+GEV E +I +T ++ Sbjct: 87 VLCAP--DSMFIVAFQLFDKSGNGEVTFENVKEIFGQTIIH 125 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 33/74 (44%), Gaps = 5/74 (6%) Query: 96 KMAEKDTKEEILKAFRLF---DDDETGKISFKNL-KRVANELGESLTDEELQEMIDEA-D 150 + ++ E+ F + + D ++ ++ +R + ++ ++ +++ D Sbjct: 10 QTTKRGDPHELRNIFLQYASTEVDGERYMTPEDFVQRYLGLYNDPNSNPKIVQLLAGVAD 69 Query: 151 RDGDGEVNEEEFLK 164 + DG ++ +EFL Sbjct: 70 QTKDGLISYQEFLA 83 >5E1J-A nrPDB Length = 741 Score = 47.3 bits (111), Expect = 3e-06, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 42/93 (45%), Gaps = 8/93 (8%) Query: 28 DQKQE--VREAFDLFDSDGSGTIDVKELKVAMRALGF-----EPRKEEMKKMISEVDKEA 80 DQ + + +AF L DSD +G ID + L + KEE + E+D Sbjct: 320 DQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEEFGLIFDELDDTR 379 Query: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLF 113 KI+ ++F + Q +A + KEE+ F F Sbjct: 380 DFKINKDEFADLC-QAIALRFQKEEVPSLFEHF 411 Score = 43.4 bits (101), Expect = 6e-05, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 39/106 (36%), Gaps = 5/106 (4%) Query: 50 VKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFND----FLAVMTQKMAEKDTKEE 105 ++L + + R+ ++K +D + G+I N F + + K +KEE Sbjct: 309 KEQLAKQVSGMDQMKRRM-LEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPKISKEE 367 Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 F DD KI+ + + EE+ + + + Sbjct: 368 FGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHFPQ 413 Score = 43.0 bits (100), Expect = 7e-05, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 45/95 (47%), Gaps = 7/95 (7%) Query: 84 ISFNDFLAVMTQKMAEKDTKEE--ILKAFRLFDDDETGKISFKNLKRVANELGE-----S 136 + ++ F + ++++ D + + KAF L D D+ G+I ++ +L Sbjct: 303 VVYDSFKEQLAKQVSGMDQMKRRMLEKAFGLIDSDKNGEIDKNQCIKLFEQLTNYRTLPK 362 Query: 137 LTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 ++ EE + DE D D ++N++EF + + L Sbjct: 363 ISKEEFGLIFDELDDTRDFKINKDEFADLCQAIAL 397 Score = 33.4 bits (75), Expect = 0.055, Method: Composition-based stats. Identities = 12/56 (21%), Positives = 20/56 (35%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEV 76 L + K+E FD D I+ E +A+ +KEE+ + Sbjct: 356 NYRTLPKISKEEFGLIFDELDDTRDFKINKDEFADLCQAIALRFQKEEVPSLFEHF 411 >1G33-A nrPDB Length = 73 Score = 46.9 bits (110), Expect = 4e-06, Method: Composition-based stats. Identities = 17/73 (23%), Positives = 37/73 (50%), Gaps = 3/73 (4%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGES---LTDEELQEMIDEADRDGDGE 156 + +++ K F + D D++G I L + L+ +E + ++ D+DGDG+ Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGK 60 Query: 157 VNEEEFLKIMKKT 169 + EEF ++ ++ Sbjct: 61 IGVEEFSTLVAES 73 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALG---FEPRKEEMKKMISEVDKEATGKISFN 87 +V++ F + D D SG I+ EL ++ + +E K +++ DK+ GKI Sbjct: 5 DDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGKIGVE 64 Query: 88 DFLAVMTQ 95 +F ++ + Sbjct: 65 EFSTLVAE 72 Score = 28.4 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 12/66 (18%), Positives = 29/66 (43%), Gaps = 2/66 (3%) Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE--KDTKEEILKAFRLFDDDETGK 120 +++KK+ +DK+ +G I ++ +++ ++ + +E D D GK Sbjct: 1 MKSADDVKKVFHILDKDKSGFIEEDELGSILKGFSSDARDLSAKETKTLMAAGDKDGDGK 60 Query: 121 ISFKNL 126 I + Sbjct: 61 IGVEEF 66 >4GFT-A nrPDB Length = 69 Score = 46.5 bits (109), Expect = 5e-06, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 38/66 (57%), Gaps = 2/66 (3%) Query: 99 EKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVN 158 +KD EE++K F FD++ TG ++ +K + G++LTD+E + ++ + + ++ Sbjct: 2 DKDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDN--ID 59 Query: 159 EEEFLK 164 + F + Sbjct: 60 YKLFCE 65 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 27/63 (42%), Gaps = 2/63 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 +D +E+ + F FD++ +G + ++K + G +E ++ E I + Sbjct: 3 KDNVEELIKMFAHFDNNSTGYLTKSQMKNILTTWGDALTDQEAIDALNAFSSEDN--IDY 60 Query: 87 NDF 89 F Sbjct: 61 KLF 63 >2PMY-A nrPDB Length = 91 Score = 46.1 bits (108), Expect = 7e-06, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 28/62 (45%), Gaps = 2/62 (3%) Query: 28 DQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFN 87 ++ +R F D++ SG ++ +E + L P E + +D + G I+F Sbjct: 24 EELARLRSVFAACDANRSGRLEREEFRALCTELRVRPADAE--AVFQRLDADRDGAITFQ 81 Query: 88 DF 89 +F Sbjct: 82 EF 83 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 11/72 (15%), Positives = 28/72 (38%), Gaps = 2/72 (2%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + + + F D + +G++ + + + EL + + + + D D Sbjct: 16 FQGADGDGEELARLRSVFAACDANRSGRLEREEFRALCTEL--RVRPADAEAVFQRLDAD 73 Query: 153 GDGEVNEEEFLK 164 DG + +EF + Sbjct: 74 RDGAITFQEFAR 85 Score = 27.6 bits (60), Expect = 2.7, Method: Composition-based stats. Identities = 6/24 (25%), Positives = 8/24 (33%) Query: 34 REAFDLFDSDGSGTIDVKELKVAM 57 F D+D G I +E Sbjct: 64 EAVFQRLDADRDGAITFQEFARGF 87 >5XOP-A nrPDB Length = 66 Score = 44.6 bits (104), Expect = 2e-05, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 25/61 (40%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 F D +G G + +E+K + ++ ++ + +DK+ G I F +F Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKFY 62 Query: 94 T 94 Sbjct: 63 G 63 Score = 41.5 bits (96), Expect = 2e-04, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 30/58 (51%) Query: 107 LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 F+ D + G +S++ +K ++ ++ LQ + D+DGDG ++ EEF K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAK 60 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 25/64 (39%), Gaps = 1/64 (1%) Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + + E+D G +S+ + + K ++ + F+ D D G I F+ + Sbjct: 3 EALFKEIDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDKDGDGFIDFEEFAKF 61 Query: 130 ANEL 133 + Sbjct: 62 YGSI 65 Score = 29.9 bits (66), Expect = 0.50, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 18/44 (40%), Gaps = 2/44 (4%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 K V K + +Q ++ F D DG G ID +E + Sbjct: 23 KAFVSKKRAIKNEQLLQL--IFKSIDKDGDGFIDFEEFAKFYGS 64 Score = 28.0 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 143 QEMIDEADRDGDGEVNEEEFLKIMKK 168 + + E D +GDG V+ EE + K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSK 28 >2E6W-A nrPDB Length = 100 Score = 43.8 bits (102), Expect = 3e-05, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 38/92 (41%), Gaps = 12/92 (13%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRA------------LGFEPRKEEMKKMISEVDK 78 ++++ AF+L+D + G I +E+ M++ L + E +++ ++D+ Sbjct: 9 EKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMDR 68 Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 G ++ +FL + + + Sbjct: 69 NQDGVVTIEEFLEACQKDENIMSSMQLFENVI 100 Score = 43.4 bits (101), Expect = 5e-05, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 37/84 (44%), Gaps = 12/84 (14%) Query: 97 MAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN----ELG--------ESLTDEELQE 144 E++ AF L+D ++ G I+ + + + +G E E ++ Sbjct: 2 SHMGTVHEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVER 61 Query: 145 MIDEADRDGDGEVNEEEFLKIMKK 168 ++ DR+ DG V EEFL+ +K Sbjct: 62 FFEKMDRNQDGVVTIEEFLEACQK 85 Score = 33.0 bits (74), Expect = 0.060, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 25/77 (32%), Gaps = 11/77 (14%) Query: 66 KEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTK-----------EEILKAFRLFD 114 E++K + D G I+ + LA+M E + + F D Sbjct: 8 HEKLKWAFNLYDINKDGYITKEEMLAIMKSIYDMMGRHTYPILREDAPAEHVERFFEKMD 67 Query: 115 DDETGKISFKNLKRVAN 131 ++ G ++ + Sbjct: 68 RNQDGVVTIEEFLEACQ 84 >6AGI-A nrPDB Length = 382 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 30/169 (17%), Positives = 61/169 (36%), Gaps = 13/169 (7%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAM-RA 59 + F K A +++ L Q + + F + S+G TI ++ + R Sbjct: 213 LVHFFGKKGKAELNFEDFYRFMDNL---QTEVLEIEFLSY-SNGMNTISEEDFAHILLRY 268 Query: 60 LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETG 119 E ++ + I+F++F + + E+ A +++ Sbjct: 269 TNVENTSVFLENV--RYSIPEEKGITFDEFRSFF----QFLNNLEDFAIALNMYNFASR- 321 Query: 120 KISFKNLKR-VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 I KR V G + + + D D D +++ +EF+ IMK Sbjct: 322 SIGQDEFKRAVYVATGLKFSPHLVNTVFKIFDVDKDDQLSYKEFIGIMK 370 Score = 32.6 bits (73), Expect = 0.092, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 39/103 (37%), Gaps = 21/103 (20%) Query: 63 EPRKEEMKKMISEV------------DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF 110 K+E+ +M++E + + G IS+ ++L ++ AF Sbjct: 55 SLSKQELNQMLAETPPVWKGSSKLFRNLKEKGVISYTEYLFLL---CILTKPHAGFRIAF 111 Query: 111 RLFDDDETGKISFKN---LKRVANELGESLT---DEELQEMID 147 +FD D + K L+ + + E DEE + M+ Sbjct: 112 NMFDTDGNEMVDKKEFLVLQEIFRKKNEKREIKGDEEKRAMLR 154 Score = 28.0 bits (61), Expect = 2.0, Method: Composition-based stats. Identities = 10/21 (47%), Positives = 15/21 (71%) Query: 33 VREAFDLFDSDGSGTIDVKEL 53 R AF++FD+DG+ +D KE Sbjct: 107 FRIAFNMFDTDGNEMVDKKEF 127 >5CUY-A nrPDB Length = 414 Score = 43.8 bits (102), Expect = 4e-05, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 32/78 (41%), Gaps = 2/78 (2%) Query: 13 TSYKRKVGPKPELTEDQKQEVREA-FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKK 71 + K + T+ +++ F FD G + +++ R LG ++K Sbjct: 60 SELDLAAYDKDDFTQPMIKKIMSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKA 119 Query: 72 MISEVDKEATGKISFNDF 89 M +E++ G ++F F Sbjct: 120 MKAEINA-IDGHVTFEKF 136 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 46/100 (46%), Gaps = 12/100 (12%) Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKIS 122 EP +E + + +SE+D A K F + K+ + + F FD G ++ Sbjct: 49 EPIQEAVDRKVSELDLAAYDKDDFTQPM-----------IKKIMSRLFSAFDVTHLGYLT 97 Query: 123 FKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 ++ V LG +++D +++ M E + DG V E+F Sbjct: 98 PDKVEEVCRYLGRNMSDGDVKAMKAEINA-IDGHVTFEKF 136 >1CB1-A nrPDB Length = 78 Score = 41.9 bits (97), Expect = 1e-04, Method: Composition-based stats. Identities = 21/75 (28%), Positives = 38/75 (50%), Gaps = 4/75 (5%) Query: 100 KDTKEEILKAFRLFDDDE--TGKISFKNLKRVANELGESL--TDEELQEMIDEADRDGDG 155 + + E+ F + E ++S + LK++ SL L ++ E D++GDG Sbjct: 3 QKSPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDG 62 Query: 156 EVNEEEFLKIMKKTN 170 EV+ EEF ++KK + Sbjct: 63 EVSFEEFQVLVKKIS 77 Score = 33.8 bits (76), Expect = 0.042, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 30/67 (44%), Gaps = 4/67 (5%) Query: 27 EDQKQEVREAFDLFD-SDGS-GTIDVKELKVAMRA--LGFEPRKEEMKKMISEVDKEATG 82 + E++ F+ + +G + +ELK ++A + + E+DK G Sbjct: 3 QKSPAELKSIFEKYAAKEGDPNQLSKEELKQLIQAEFPSLLKGPRTLDDLFQELDKNGDG 62 Query: 83 KISFNDF 89 ++SF +F Sbjct: 63 EVSFEEF 69 >2NCO-A nrPDB Length = 102 Score = 41.9 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 37/73 (50%), Gaps = 7/73 (9%) Query: 104 EEILKAFRLFDDDETGKISFKN----LKRVANELG---ESLTDEELQEMIDEADRDGDGE 156 + + F+ +D D +G++ LK E+G + T E+++ + AD + DG Sbjct: 15 DVARRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGS 74 Query: 157 VNEEEFLKIMKKT 169 V+ EE+ ++ K+ Sbjct: 75 VSLEEYEDLIIKS 87 Score = 40.3 bits (93), Expect = 5e-04, Method: Composition-based stats. Identities = 20/79 (25%), Positives = 36/79 (45%), Gaps = 7/79 (8%) Query: 34 REAFDLFDSDGSGTIDVKE----LKVAMRALG---FEPRKEEMKKMISEVDKEATGKISF 86 R F +D DGSG + E LK +G F P KE++K + D + G +S Sbjct: 18 RRLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSL 77 Query: 87 NDFLAVMTQKMAEKDTKEE 105 ++ ++ + + + + E Sbjct: 78 EEYEDLIIKSLQKAGIRVE 96 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 10/66 (15%), Positives = 29/66 (43%), Gaps = 6/66 (9%) Query: 71 KMISEVDKEATGKISFNDFLAVMTQKMAEKDT------KEEILKAFRLFDDDETGKISFK 124 ++ DK+ +G++ ++ ++ AE KE++ ++ D + G +S + Sbjct: 19 RLFKRYDKDGSGQLQDDEIAGLLKDTYAEMGMSNFTPTKEDVKIWLQMADTNSDGSVSLE 78 Query: 125 NLKRVA 130 + + Sbjct: 79 EYEDLI 84 >2M7M-A nrPDB Length = 66 Score = 41.1 bits (95), Expect = 3e-04, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 25/61 (40%) Query: 34 REAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVM 93 F D +G G + +E+K + ++ ++ + +D + G+I N+F Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKFY 62 Query: 94 T 94 Sbjct: 63 G 63 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 30/58 (51%) Query: 107 LKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 F+ D + G +S++ +K ++ ++ LQ + D DG+GE+++ EF K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAK 60 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 24/64 (37%), Gaps = 1/64 (1%) Query: 70 KKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRV 129 + + E+D G +S+ + + K ++ + F+ D D G+I + Sbjct: 3 EALFKEIDVNGDGAVSYEE-VKAFVSKKRAIKNEQLLQLIFKSIDADGNGEIDQNEFAKF 61 Query: 130 ANEL 133 + Sbjct: 62 YGSI 65 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 9/26 (34%), Positives = 14/26 (53%) Query: 143 QEMIDEADRDGDGEVNEEEFLKIMKK 168 + + E D +GDG V+ EE + K Sbjct: 3 EALFKEIDVNGDGAVSYEEVKAFVSK 28 Score = 27.2 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRA 59 K V K + +Q ++ F D+DG+G ID E + Sbjct: 23 KAFVSKKRAIKNEQLLQL--IFKSIDADGNGEIDQNEFAKFYGS 64 >1ZFS-A nrPDB Length = 93 Score = 40.7 bits (94), Expect = 3e-04, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 28/53 (52%), Gaps = 5/53 (9%) Query: 120 KISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 K+S K LK + L + + +++ E D +GDGEV+ +EF+ ++ Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVA 79 Score = 33.8 bits (76), Expect = 0.041, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 27/53 (50%), Gaps = 5/53 (9%) Query: 47 TIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 + KELK ++ L + + + K++ E+D+ G++ F +F+ ++ Sbjct: 27 KLSKKELKDLLQTELSSFLDVQKDADAVDKIMKELDENGDGEVDFQEFVVLVA 79 >5CUU-A nrPDB Length = 414 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 23/102 (22%), Positives = 47/102 (46%), Gaps = 12/102 (11%) Query: 61 GFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGK 120 +P E K+ ++E D A GK ++F M K + + F FD + G Sbjct: 46 NVKPLPEACKRNVTEFDLVAYGK---DEFTLSM--------EKRVMARMFSAFDVTQLGY 94 Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 + + ++ + LG + ++++++M E + DG + E+F Sbjct: 95 LEERKIEHMCKYLGRVMNEDDVKQMKSEINA-IDGHITFEKF 135 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 2/78 (2%) Query: 13 TSYKRKVGPKPELTEDQKQEVREA-FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKK 71 T + K E T ++ V F FD G ++ ++++ + LG ++++K+ Sbjct: 59 TEFDLVAYGKDEFTLSMEKRVMARMFSAFDVTQLGYLEERKIEHMCKYLGRVMNEDDVKQ 118 Query: 72 MISEVDKEATGKISFNDF 89 M SE++ G I+F F Sbjct: 119 MKSEINA-IDGHITFEKF 135 >6MI5-X nrPDB Length = 117 Score = 40.3 bits (93), Expect = 4e-04, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 36/92 (39%), Gaps = 24/92 (26%) Query: 35 EAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 AFD D D GT+D KELK + ++KK+ D + G + ++LA Sbjct: 31 AAFDKLDPDKDGTLDAKELKG-------RVSEADLKKL----DPDNDGTLDKKEYLAA-- 77 Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 + F+ + D G I + L Sbjct: 78 -----------VEAQFKAANPDNDGTIDAREL 98 Score = 39.2 bits (90), Expect = 9e-04, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 41/95 (43%), Gaps = 24/95 (25%) Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 I+ D + G I + LA + AF D D+ G + K LK Sbjct: 9 IAAFDPDKDGTIDLKEALAAGS-------------AAFDKLDPDKDGTLDAKELK----- 50 Query: 133 LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +++ +L+++ D D DG ++++E+L ++ Sbjct: 51 --GRVSEADLKKL----DPDNDGTLDKKEYLAAVE 79 Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 23/122 (18%), Positives = 42/122 (34%), Gaps = 36/122 (29%) Query: 40 FDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAE 99 FD D GTID+KE A A ++D + G + +++ Sbjct: 12 FDPDKDGTIDLKEALAAGSA------------AFDKLDPDKDGTLD--------AKELKG 51 Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + ++ ++ K D D G + K ++ A+ D DG ++ Sbjct: 52 RVSEADLKK----LDPDNDGTLDKKEYLAA------------VEAQFKAANPDNDGTIDA 95 Query: 160 EE 161 E Sbjct: 96 RE 97 >4MEW-A nrPDB Length = 356 Score = 39.9 bits (92), Expect = 6e-04, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 41/114 (35%), Gaps = 9/114 (7%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEA-----TGKISFNDFLA 91 F D+D ID +L R + + ++ S GKIS+ DF+ Sbjct: 196 FWELDTDHDLLIDADDLA---RHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVW 252 Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 + + +K I FR D D G +S L+ E L ++ + Sbjct: 253 FLISEEDKKTPTS-IEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEAL 305 Score = 31.9 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 30/80 (37%), Gaps = 12/80 (15%) Query: 25 LTEDQKQ---EVREAFDLFDSDGSGTIDVKELKVAMRALGFE---------PRKEEMKKM 72 ++E+ K+ + F D DG G + + EL+ P ++ + +M Sbjct: 255 ISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQM 314 Query: 73 ISEVDKEATGKISFNDFLAV 92 + V GKI+ D Sbjct: 315 LDLVKPRTEGKITLQDLKRC 334 Score = 30.3 bits (67), Expect = 0.42, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 50/148 (33%), Gaps = 26/148 (17%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE--MKKM---------------ISE 75 ++ F + SG I EL+ + +EE + ++ E Sbjct: 139 IQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFYVIYCKFWE 198 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF-----RLFDDDETGKISFKNLKRVA 130 +D + I +D + + + + I + F R + GKIS+ + Sbjct: 199 LDTDHDLLIDADD----LARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFL 254 Query: 131 NELGESLTDEELQEMIDEADRDGDGEVN 158 + T ++ D DGDG ++ Sbjct: 255 ISEEDKKTPTSIEYWFRCMDLDGDGALS 282 >5C5V-A nrPDB Length = 342 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 24/53 (45%), Gaps = 1/53 (1%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 F FD G + +++ R LG ++K M +E++ G ++F F Sbjct: 13 FSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINA-IDGHVTFEKF 64 Score = 38.4 bits (88), Expect = 0.002, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 K+ + + F FD G ++ ++ V LG +++D +++ M E + DG V E+F Sbjct: 6 KKIMSRLFSAFDVTHLGYLTPDKVEEVCRYLGRNMSDGDVKAMKAEINA-IDGHVTFEKF 64 >1BOD-A nrPDB Length = 74 Score = 39.6 bits (91), Expect = 7e-04, Method: Composition-based stats. Identities = 24/73 (32%), Positives = 40/73 (54%), Gaps = 2/73 (2%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTD--EELQEMIDEADRDGDGEV 157 + EE+ F +D + G++S + LK + SL L E+ +E D++GDGEV Sbjct: 1 MKSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEV 60 Query: 158 NEEEFLKIMKKTN 170 + EEF ++KK + Sbjct: 61 SFEEFQVLVKKIS 73 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 33/61 (54%), Gaps = 2/61 (3%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRA--LGFEPRKEEMKKMISEVDKEATGKISFND 88 +E++ F+ +D +G G + +ELK+ ++ + ++ E+DK G++SF + Sbjct: 5 EELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEVSFEE 64 Query: 89 F 89 F Sbjct: 65 F 65 Score = 26.5 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 14/74 (18%), Positives = 35/74 (47%), Gaps = 1/74 (1%) Query: 63 EPRKEEMKKMISEVDKEATGKISFNDFLAVM-TQKMAEKDTKEEILKAFRLFDDDETGKI 121 EE+K + + DKE G++S + ++ T+ + + + F D + G++ Sbjct: 1 MKSPEELKGIFEKYDKEGDGQLSKEELKLLLQTEFPSLLKGMSTLDELFEELDKNGDGEV 60 Query: 122 SFKNLKRVANELGE 135 SF+ + + ++ + Sbjct: 61 SFEEFQVLVKKISQ 74 >6IIE-A nrPDB Length = 93 Score = 39.2 bits (90), Expect = 0.001, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 37/72 (51%), Gaps = 9/72 (12%) Query: 102 TKEEILKAFRLFDDDETGKISFKN-------LKRVANELGESLTDEE--LQEMIDEADRD 152 ++++ F+L+D D G + + RVA L +++ LQEM+ E D D Sbjct: 7 PEDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYD 66 Query: 153 GDGEVNEEEFLK 164 G G V++ E+++ Sbjct: 67 GSGSVSQAEWVR 78 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 35/72 (48%), Gaps = 9/72 (12%) Query: 30 KQEVREAFDLFDSDGSGTIDVKE-------LKVAMRALGFEPRKEE--MKKMISEVDKEA 80 + ++ F L+D+D +G +D E + L ++ + +++M+ E+D + Sbjct: 8 EDKLEFTFKLYDTDRNGILDSSEVDKIILQMMRVAEYLDWDVSELRPILQEMMKEIDYDG 67 Query: 81 TGKISFNDFLAV 92 +G +S +++ Sbjct: 68 SGSVSQAEWVRA 79 >5MKE-A nrPDB Length = 968 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 GK++F L++ G TD E++ + + D+DGD E+ E E ++ Sbjct: 732 GGGKLNFDELRQDLKGKGH--TDAEIEAIFTKYDQDGDQELTEHEHQQM 778 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 ISE ++ GK++F++ + + T EI F +D D +++ +++ ++ Sbjct: 725 ISESLRQGGGKLNFDE---LRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDD 781 Query: 133 LGESLTDEELQ 143 L + D +L Sbjct: 782 LEKEREDLDLD 792 >6D1W-A nrPDB Length = 740 Score = 38.8 bits (89), Expect = 0.001, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 GK++F L++ G TD E++ + + D+DGD E+ E E ++ Sbjct: 680 GGGKLNFDELRQDLKGKGH--TDAEIEAIFTKYDQDGDQELTEHEHQQM 726 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 ISE ++ GK++F++ + + T EI F +D D +++ +++ ++ Sbjct: 673 ISESLRQGGGKLNFDE---LRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDD 729 Query: 133 LGESLTDEELQ 143 L + D +L Sbjct: 730 LEKEREDLDLD 740 >1NSH-A nrPDB Length = 101 Score = 38.4 bits (88), Expect = 0.001, Method: Composition-based stats. Identities = 13/85 (15%), Positives = 34/85 (40%), Gaps = 7/85 (8%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETG--KISFKNLKRVANELGESLTDEE-----LQEMI 146 ++ + E ++ F+ + + +S N + T + L M+ Sbjct: 1 SRPTETERCIESLIAVFQKYAGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMM 60 Query: 147 DEADRDGDGEVNEEEFLKIMKKTNL 171 + D + DG+++ +EFL ++ + Sbjct: 61 KKLDLNSDGQLDFQEFLNLIGGLAV 85 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 15/82 (18%), Positives = 33/82 (40%), Gaps = 9/82 (10%) Query: 21 PKPELTEDQKQEVREAFDLFDSDGSG---TIDVKELKVAMRALGFEPRKEE-----MKKM 72 +P TE + + F + + G T+ E M K + + +M Sbjct: 1 SRPTETERCIESLIAVFQKY-AGKDGHSVTLSKTEFLSFMNTELAAFTKNQKDPGVLDRM 59 Query: 73 ISEVDKEATGKISFNDFLAVMT 94 + ++D + G++ F +FL ++ Sbjct: 60 MKKLDLNSDGQLDFQEFLNLIG 81 >4YBH-B nrPDB Length = 92 Score = 37.6 bits (86), Expect = 0.002, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Query: 117 ETGKISFKNLKRVAN---ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + +S K LK + +G L D E+ ++++ DR+ D EVN +E++ + Sbjct: 27 DKHTLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFL 79 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 9/51 (17%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Query: 47 TIDVKELKVAMRA---LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 T+ KELK ++ +G + + E+ +++ ++D+ +++F +++ + Sbjct: 30 TLSKKELKELIQKELTIGSKLQDAEIARLMEDLDRNKDQEVNFQEYVTFLG 80 >2L0P-A nrPDB Length = 94 Score = 37.6 bits (86), Expect = 0.003, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 28/53 (52%), Gaps = 5/53 (9%) Query: 120 KISFKNLKRVANELGESLTDEE-----LQEMIDEADRDGDGEVNEEEFLKIMK 167 K+S K LK + D + + +++ E D +GDGEV+ +E++ ++ Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVA 80 Score = 29.9 bits (66), Expect = 0.51, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 27/53 (50%), Gaps = 5/53 (9%) Query: 47 TIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 + KELK ++ L + + + K++ E+D+ G++ F +++ ++ Sbjct: 28 KLSKKELKELLQTELSGFLDAQKDVDAVDKVMKELDENGDGEVDFQEYVVLVA 80 >1QLS-A nrPDB Length = 99 Score = 37.2 bits (85), Expect = 0.003, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 34/87 (39%), Gaps = 7/87 (8%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDD-DETG-KISFKNLKRVANELGESLTDEE-----LQE 144 + + + E ++ F+ D KIS N + T + L Sbjct: 1 MAKRPTETERCIESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDR 60 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKTNL 171 M+ + D D DG+++ +EFL ++ + Sbjct: 61 MMKKLDLDSDGQLDFQEFLNLIGGLAI 87 Score = 32.2 bits (72), Expect = 0.11, Method: Composition-based stats. Identities = 16/83 (19%), Positives = 36/83 (43%), Gaps = 7/83 (8%) Query: 19 VGPKPELTEDQKQEVREAF-DLFDSDGSGT-IDVKELKVAMRALGFEPRKEE-----MKK 71 + +P TE + + F DG+ T I E + M + + + + Sbjct: 1 MAKRPTETERCIESLIAIFQKHAGRDGNNTKISKTEFLIFMNTELAAFTQNQKDPGVLDR 60 Query: 72 MISEVDKEATGKISFNDFLAVMT 94 M+ ++D ++ G++ F +FL ++ Sbjct: 61 MMKKLDLDSDGQLDFQEFLNLIG 83 >4I5K-A nrPDB Length = 285 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 47/132 (35%), Gaps = 12/132 (9%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKK--MISEVDKEATGKISFNDFLAVMT 94 F D+D I +L E + + + G++S+ DF+ + Sbjct: 122 FWELDTDHDLYISQADLSRYNDQASSSRIIERIFSGAVTRGKTIQKEGRMSYADFVWFLI 181 Query: 95 QKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ---------EM 145 + +++ I FR D D G +S L+ E E + ++ +M Sbjct: 182 SEEDKRNPTS-IEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQM 240 Query: 146 IDEADRDGDGEV 157 +D DG++ Sbjct: 241 LDLVKPAVDGKI 252 Score = 33.0 bits (74), Expect = 0.069, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 12/80 (15%) Query: 25 LTEDQKQE---VREAFDLFDSDGSGTIDVKELKVA-------MRALGFEPR--KEEMKKM 72 ++E+ K+ + F D DG G + + EL+ M A+G EP + + +M Sbjct: 181 ISEEDKRNPTSIEYWFRCMDVDGDGVLSMYELEYFYEEQCERMEAMGIEPLPFHDLLCQM 240 Query: 73 ISEVDKEATGKISFNDFLAV 92 + V GKI+ D Sbjct: 241 LDLVKPAVDGKITLRDLKRC 260 >2I18-A nrPDB Length = 64 Score = 37.2 bits (85), Expect = 0.004, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAV 92 ++ + L D DG G + +E+ + G E E++ K D G I+ +FL Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMK----ADANGDGYITLEEFLEF 62 Score = 33.4 bits (75), Expect = 0.049, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 32/59 (54%), Gaps = 4/59 (6%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK 164 + ++L D D GK++ + + + G E++ E + +AD +GDG + EEFL+ Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGI----EKVAEQVMKADANGDGYITLEEFLE 61 Score = 28.4 bits (62), Expect = 1.8, Method: Composition-based stats. Identities = 9/58 (15%), Positives = 24/58 (41%), Gaps = 5/58 (8%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 +K + +D + GK++ + + + EK ++ + D + G I+ + Sbjct: 7 LKVLYKLMDVDGDGKLTKEEVTSFFKKHGIEKVAEQVMKA-----DANGDGYITLEEF 59 >3LCP-C nrPDB Length = 93 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 20/90 (22%), Positives = 38/90 (42%), Gaps = 12/90 (13%) Query: 90 LAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN--------ELGESLTDEE 141 + V+ + AE +E L F++ D D + L E ++++E Sbjct: 4 MGVINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDE 63 Query: 142 LQEMIDEA----DRDGDGEVNEEEFLKIMK 167 L +ID D++ DG ++ EF K ++ Sbjct: 64 LINIIDGVLRDDDKNNDGYIDYAEFAKSLQ 93 Score = 30.3 bits (67), Expect = 0.41, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFE--------PRKEEMKKMISEV----DKEATGKI 84 F + D DG+ +D EL A+ + E ++E+ +I V DK G I Sbjct: 24 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 83 Query: 85 SFNDF 89 + +F Sbjct: 84 DYAEF 88 >2VRG-A nrPDB Length = 124 Score = 36.5 bits (83), Expect = 0.006, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 12/88 (13%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN--------ELGESLTDEELQ 143 V+ + AE +E L F++ D D + L E ++++EL Sbjct: 37 VINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELI 96 Query: 144 EMIDEA----DRDGDGEVNEEEFLKIMK 167 +ID D++ DG ++ EF K ++ Sbjct: 97 NIIDGVLRDDDKNNDGYIDYAEFAKSLQ 124 Score = 30.3 bits (67), Expect = 0.41, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFE--------PRKEEMKKMISEV----DKEATGKI 84 F + D DG+ +D EL A+ + E ++E+ +I V DK G I Sbjct: 55 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 114 Query: 85 SFNDF 89 + +F Sbjct: 115 DYAEF 119 >2LUC-A nrPDB Length = 105 Score = 36.5 bits (83), Expect = 0.007, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 30/71 (42%), Gaps = 9/71 (12%) Query: 104 EEILKAFRLFDDDETGK---ISFKNLKRVANELGESLTDEE-----LQEMIDEADRDGDG 155 E ++ F+ + + G +S N + T + L M+ + D + DG Sbjct: 15 ESLIAVFQKYAG-KDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMKKLDTNSDG 73 Query: 156 EVNEEEFLKIM 166 +++ EFL ++ Sbjct: 74 QLDFSEFLNLI 84 Score = 29.9 bits (66), Expect = 0.64, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 32/80 (40%), Gaps = 9/80 (11%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGT---IDVKELKVAMRALGFEPRKEE-----MKKMIS 74 P TE + + F + + G + E M K + + +M+ Sbjct: 7 PTETERCIESLIAVFQKY-AGKDGYNYTLSKTEFLSFMNTELAAFTKNQKDPGVLDRMMK 65 Query: 75 EVDKEATGKISFNDFLAVMT 94 ++D + G++ F++FL ++ Sbjct: 66 KLDTNSDGQLDFSEFLNLIG 85 >2KGR-A nrPDB Length = 111 Score = 36.1 bits (82), Expect = 0.007, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 36/79 (45%), Gaps = 2/79 (2%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + + + ++ + + F D +G ++ + + + SL +L + + +D D Sbjct: 3 VAEWAVPQSSRLKYRQLFNSHDKTMSGHLTGPQARTIL--MQSSLPQAQLASIWNLSDID 60 Query: 153 GDGEVNEEEFLKIMKKTNL 171 DG++ EEF+ M ++ Sbjct: 61 QDGKLTAEEFILAMHLIDV 79 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 10/69 (14%), Positives = 31/69 (44%), Gaps = 2/69 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 + + + + R+ F+ D SG + + + + + + ++ + + D + GK+ Sbjct: 8 VPQSSRLKYRQLFNSHDKTMSGHLTGPQARTIL--MQSSLPQAQLASIWNLSDIDQDGKL 65 Query: 85 SFNDFLAVM 93 + +F+ M Sbjct: 66 TAEEFILAM 74 Score = 29.5 bits (65), Expect = 0.80, Method: Composition-based stats. Identities = 9/68 (13%), Positives = 30/68 (44%), Gaps = 3/68 (4%) Query: 71 KMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVA 130 ++ + DK +G ++ ++ Q + ++ + L D D+ GK++ + Sbjct: 18 QLFNSHDKTMSGHLTGPQARTILMQSSLPQ---AQLASIWNLSDIDQDGKLTAEEFILAM 74 Query: 131 NELGESLT 138 + + +++ Sbjct: 75 HLIDVAMS 82 >3A4U-B nrPDB Length = 143 Score = 36.1 bits (82), Expect = 0.008, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 37/88 (42%), Gaps = 12/88 (13%) Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN--------ELGESLTDEELQ 143 V+ + AE +E L F++ D D + L E ++++EL Sbjct: 56 VINKPEAEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELI 115 Query: 144 EMIDEA----DRDGDGEVNEEEFLKIMK 167 +ID D++ DG ++ EF K ++ Sbjct: 116 NIIDGVLRDDDKNNDGYIDYAEFAKSLQ 143 Score = 29.9 bits (66), Expect = 0.52, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFE--------PRKEEMKKMISEV----DKEATGKI 84 F + D DG+ +D EL A+ + E ++E+ +I V DK G I Sbjct: 74 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 133 Query: 85 SFNDF 89 + +F Sbjct: 134 DYAEF 138 >4I5L-B nrPDB Length = 413 Score = 35.7 bits (81), Expect = 0.009, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 40/110 (36%), Gaps = 16/110 (14%) Query: 25 LTEDQKQ---EVREAFDLFDSDGSGTIDVKELKVAMRALGFE---------PRKEEMKKM 72 ++E+ K+ + F D DG G + + EL+ P ++ + +M Sbjct: 263 ISEEDKKTPTSIEYWFRCMDLDGDGALSMFELEYFYEEQCRRLDSMAIEALPFQDCLCQM 322 Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKIS 122 + V GKI+ D + + + + D ++ +IS Sbjct: 323 LDLVKPRTEGKITLQD----LKRCKLANVFFDTFFNIEKYLDHEQKEQIS 368 Score = 31.5 bits (70), Expect = 0.20, Method: Composition-based stats. Identities = 25/148 (16%), Positives = 50/148 (33%), Gaps = 26/148 (17%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEE--MKKM---------------ISE 75 ++ F + SG I EL+ + +EE + ++ E Sbjct: 147 IQRIFYAVNRSWSGRITCAELRRSSFLQNVALLEEEADINQLTEFFSYEHFYVIYCKFWE 206 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAF-----RLFDDDETGKISFKNLKRVA 130 +D + I +D + + + + I + F R + GKIS+ + Sbjct: 207 LDTDHDLLIDADD----LARHNDHALSTKMIDRIFSGAVTRGRKVQKEGKISYADFVWFL 262 Query: 131 NELGESLTDEELQEMIDEADRDGDGEVN 158 + T ++ D DGDG ++ Sbjct: 263 ISEEDKKTPTSIEYWFRCMDLDGDGALS 290 >2JTT-A nrPDB Length = 90 Score = 35.7 bits (81), Expect = 0.010, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 30/53 (56%), Gaps = 3/53 (5%) Query: 117 ETGKISFKNLKRVAN---ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 + +S K LK + +G L D E+ +++D+ DR+ D EVN +E++ + Sbjct: 25 DKHTLSKKELKELIQKELTIGSKLQDAEIVKLMDDLDRNKDQEVNFQEYITFL 77 Score = 29.9 bits (66), Expect = 0.57, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Query: 47 TIDVKELKVAMRA---LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 T+ KELK ++ +G + + E+ K++ ++D+ +++F +++ + Sbjct: 28 TLSKKELKELIQKELTIGSKLQDAEIVKLMDDLDRNKDQEVNFQEYITFLG 78 >4YGB-B nrPDB Length = 104 Score = 35.7 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 35/86 (40%), Gaps = 12/86 (13%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN--------ELGESLTDEELQEM 145 + M E +E L F++ D D + L E ++++EL + Sbjct: 19 GRHMLEMSPQELQLHYFKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINI 78 Query: 146 IDEA----DRDGDGEVNEEEFLKIMK 167 ID D++ DG ++ EF K ++ Sbjct: 79 IDGVLRDDDKNNDGYIDYAEFAKSLQ 104 Score = 29.2 bits (64), Expect = 0.93, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 12/65 (18%) Query: 37 FDLFDSDGSGTIDVKELKVAMRALGFE--------PRKEEMKKMISEV----DKEATGKI 84 F + D DG+ +D EL A+ + E ++E+ +I V DK G I Sbjct: 35 FKMHDYDGNNLLDGLELSTAITHVHKEEGSEQAPLMSEDELINIIDGVLRDDDKNNDGYI 94 Query: 85 SFNDF 89 + +F Sbjct: 95 DYAEF 99 >5X2E-A nrPDB Length = 80 Score = 35.7 bits (81), Expect = 0.011, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 22/57 (38%), Gaps = 2/57 (3%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDF 89 F D DG+ I EL+ + +P ++K D + TG I+ F Sbjct: 3 FINIFVSIDKDGTNVISYPELEQYVAENNLDPS--MVEKWKQLFDPDNTGSITLETF 57 Score = 34.2 bits (77), Expect = 0.034, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 24/61 (39%), Gaps = 2/61 (3%) Query: 104 EEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 + + F D D T IS+ L++ E +L +++ D D G + E F Sbjct: 1 DSFINIFVSIDKDGTNVISYPELEQYVAE--NNLDPSMVEKWKQLFDPDNTGSITLETFC 58 Query: 164 K 164 Sbjct: 59 S 59 Score = 29.9 bits (66), Expect = 0.59, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 25/55 (45%), Gaps = 3/55 (5%) Query: 72 MISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 + +DK+ T IS+ + + + + E+ +LFD D TG I+ + Sbjct: 6 IFVSIDKDGTNVISYPELEQYVAENNLDPSMVEKWK---QLFDPDNTGSITLETF 57 >4L9M-A nrPDB Length = 559 Score = 35.3 bits (80), Expect = 0.013, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 19/58 (32%), Gaps = 10/58 (17%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 + + D + G IS +F + +F + D D G IS + Sbjct: 427 VDSVFKNYDHDQDGYISQEEFEKIAAS----------FPFSFCVMDKDREGLISRDEI 474 Score = 34.9 bits (79), Expect = 0.016, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 31/68 (45%), Gaps = 10/68 (14%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLK- 164 + F+ +D D+ G IS + +++A S D+D +G ++ +E Sbjct: 427 VDSVFKNYDHDQDGYISQEEFEKIAASFPFS---------FCVMDKDREGLISRDEITAY 477 Query: 165 IMKKTNLY 172 M+ +++Y Sbjct: 478 FMRASSIY 485 Score = 30.3 bits (67), Expect = 0.43, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 9/60 (15%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 F +D D G I +E + + F +DK+ G IS ++ A + Sbjct: 430 VFKNYDHDQDGYISQEEFEKIAASFPFS---------FCVMDKDREGLISRDEITAYFMR 480 Score = 30.3 bits (67), Expect = 0.49, Method: Composition-based stats. Identities = 6/39 (15%), Positives = 17/39 (43%), Gaps = 4/39 (10%) Query: 24 ELTEDQKQEVREAFD----LFDSDGSGTIDVKELKVAMR 58 +++++ +++ +F + D D G I E+ Sbjct: 441 YISQEEFEKIAASFPFSFCVMDKDREGLISRDEITAYFM 479 >6DU8-A nrPDB Length = 805 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 36/93 (38%), Gaps = 7/93 (7%) Query: 50 VKELKVA-MRALGFEPRK------EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDT 102 EL+++ + G+ +E + +V + +I F DF + + + Sbjct: 575 KDELQLSDLLKQGYNKTLLRLRLRKERVSDVQKVLQGGEQEIQFEDFTNTLRELGHAEHE 634 Query: 103 KEEILKAFRLFDDDETGKISFKNLKRVANELGE 135 E+ F FD D + K +++ +L E Sbjct: 635 ITELTATFTKFDRDGNRILDEKEQEKMRQDLEE 667 Score = 31.1 bits (69), Expect = 0.24, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 18/46 (39%), Gaps = 2/46 (4%) Query: 9 NVASTSYKRKVGPKPEL--TEDQKQEVREAFDLFDSDGSGTIDVKE 52 ++ EL E + E+ F FD DG+ +D KE Sbjct: 612 GEQEIQFEDFTNTLRELGHAEHEITELTATFTKFDRDGNRILDEKE 657 >4C0K-A nrPDB Length = 423 Score = 35.3 bits (80), Expect = 0.014, Method: Composition-based stats. Identities = 30/155 (19%), Positives = 60/155 (38%), Gaps = 13/155 (8%) Query: 19 VGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKEL----KVAMRALGFEPRKEEMKKMIS 74 + + ELT K+ + F + D DG ++ EL + +E+K +I Sbjct: 1 MMEEQELTSACKKSLVRIFKICDIDGDNLLNDYELNLFQRRCFNTPLQPQILDEVKAVIQ 60 Query: 75 EVDKEA--TGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 + + ++ FL + ++ E R F ++ ++ + L+ Sbjct: 61 KNVPDGIYNDAVTLKGFL-FLHCLFIQRGRNETTWAVLRRFGYNDQLEMCQEYLRPPLKI 119 Query: 133 LGESLTD------EELQEMIDEADRDGDGEVNEEE 161 S T+ + L + + DRDGDG ++ EE Sbjct: 120 PPGSSTELSHRGQQFLIAVFERYDRDGDGALSPEE 154 Score = 34.5 bits (78), Expect = 0.022, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 20/45 (44%) Query: 20 GPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEP 64 G EL+ +Q + F+ +D DG G + +E K+ P Sbjct: 122 GSSTELSHRGQQFLIAVFERYDRDGDGALSPEEHKMLFSTCPAAP 166 >1J7Q-A nrPDB Length = 86 Score = 35.3 bits (80), Expect = 0.015, Method: Composition-based stats. Identities = 16/71 (22%), Positives = 33/71 (46%), Gaps = 2/71 (2%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEA--DRDGDGEV 157 + K+E +K F +FD + + + +LG++ T E + ++ EA + + Sbjct: 10 PEEKDECMKIFDIFDRNAENIAPVSDTMDMLTKLGQTYTKRETEAIMKEARGPKGDKKNI 69 Query: 158 NEEEFLKIMKK 168 EE+L + K Sbjct: 70 GPEEWLTLCSK 80 Score = 33.8 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 31/73 (42%), Gaps = 2/73 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVD--KEATG 82 L ++K E + FD+FD + V + + LG K E + ++ E K Sbjct: 8 LGPEEKDECMKIFDIFDRNAENIAPVSDTMDMLTKLGQTYTKRETEAIMKEARGPKGDKK 67 Query: 83 KISFNDFLAVMTQ 95 I ++L + ++ Sbjct: 68 NIGPEEWLTLCSK 80 >1KQV-A nrPDB Length = 79 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 14/31 (45%), Positives = 22/31 (70%) Query: 140 EELQEMIDEADRDGDGEVNEEEFLKIMKKTN 170 L E+ +E D++GDGEV+ EEF ++KK + Sbjct: 48 STLDELFEELDKNGDGEVSFEEFQVLVKKIS 78 Score = 26.5 bits (57), Expect = 5.9, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 16/30 (53%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGF 62 + E F+ D +G G + +E +V ++ + Sbjct: 50 LDELFEELDKNGDGEVSFEEFQVLVKKISQ 79 >1DJX-A nrPDB Length = 624 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 34/89 (38%), Gaps = 8/89 (8%) Query: 26 TEDQKQEVRE----AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEAT 81 + DQ+Q+++ D + ++ KELK ++ L + +K+ E D T Sbjct: 2 SMDQRQKLQHWIHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECDHSQT 61 Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAF 110 + + + EI +AF Sbjct: 62 DSLEDEEIETFY----KMLTQRAEIDRAF 86 Score = 34.9 bits (79), Expect = 0.017, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 36/81 (44%), Gaps = 7/81 (8%) Query: 91 AVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEAD 150 ++ ++ + + KA D ++ K++FK LK EL + D +++ E D Sbjct: 2 SMDQRQKLQHWIHSCLRKA----DKNKDNKMNFKELKDFLKELNIQVDDGYARKIFRECD 57 Query: 151 RDGDGEVNEEE---FLKIMKK 168 + +EE F K++ + Sbjct: 58 HSQTDSLEDEEIETFYKMLTQ 78 Score = 32.6 bits (73), Expect = 0.097, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 31/81 (38%), Gaps = 4/81 (4%) Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 + + + DK K++F + + + + D K FR D +T + + ++ Sbjct: 13 IHSCLRKADKNKDNKMNFKELKDFLKELNIQVDDG-YARKIFRECDHSQTDSLEDEEIET 71 Query: 129 VANELGESLTDEELQEMIDEA 149 L + E+ +EA Sbjct: 72 FYKMLTQR---AEIDRAFEEA 89 >2MA2-A nrPDB Length = 81 Score = 34.9 bits (79), Expect = 0.019, Method: Composition-based stats. Identities = 13/77 (16%), Positives = 29/77 (37%), Gaps = 8/77 (10%) Query: 28 DQKQEVRE-AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 + +++ E F FD DG G I +E ++ ++D+ G IS Sbjct: 9 EHIEKMVESVFRNFDVDGDGHISQEEFQIIRG-------NFPYLSAFGDLDQNQDGCISR 61 Query: 87 NDFLAVMTQKMAEKDTK 103 + ++ + + + Sbjct: 62 EEMVSYFLRSSSVLGGR 78 Score = 34.2 bits (77), Expect = 0.029, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 32/78 (41%), Gaps = 7/78 (8%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRD 152 + Q + + ++ + FR FD D G IS + + + + D++ Sbjct: 2 LDQALVVEHIEKMVESVFRNFDVDGDGHISQEEFQIIRGNFPY-------LSAFGDLDQN 54 Query: 153 GDGEVNEEEFLKIMKKTN 170 DG ++ EE + +++ Sbjct: 55 QDGCISREEMVSYFLRSS 72 >5VP3-A nrPDB Length = 206 Score = 33.8 bits (76), Expect = 0.037, Method: Composition-based stats. Identities = 36/189 (19%), Positives = 68/189 (35%), Gaps = 28/189 (14%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQK-----QEVREAFDLFDSDGSGTIDVKE---LKVA 56 ++N S Y R VG + + + + + FD FD D G + + E Sbjct: 3 LDETNNESYRYLRSVGNTWKFNVEDVHPKMLERLYKRFDTFDLDTDGKMTMDEIMYWPDR 62 Query: 57 MRALGFEPRKEEMKKMISEVDK----------EATGKISFNDFLAVMTQKMAEKDTKEEI 106 MR L E+++KM + V + + + V + E++ + E Sbjct: 63 MRQL-VNATDEQVEKMRAAVHTFFFHKGVDPVNGLKREDWVEANRVFAEAERERERRGEP 121 Query: 107 L-------KAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + + DDD G + + LK + + E +AD D G++ Sbjct: 122 SLIALLSNAYYDVLDDDGDGTVDVEELKTMMKAF--DVPQEAAYTFFQKADTDKTGKLER 179 Query: 160 EEFLKIMKK 168 E + + +K Sbjct: 180 PELVHLFRK 188 Score = 27.2 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 19/57 (33%), Gaps = 3/57 (5%) Query: 87 NDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQ 143 + +M + E F+ D D+TGK+ L + + D + Sbjct: 146 EELKTMMKAFDVPQ---EAAYTFFQKADTDKTGKLERPELVHLFRKFWMEPYDPQWD 199 >1C07-A nrPDB Length = 95 Score = 33.8 bits (76), Expect = 0.044, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 26/69 (37%), Gaps = 2/69 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 ++ +K + E F D D G + E++ G + + S D + GK+ Sbjct: 4 VSPAEKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTL--LAHIWSLCDTKDCGKL 61 Query: 85 SFNDFLAVM 93 S + F Sbjct: 62 SKDQFALAF 70 Score = 29.9 bits (66), Expect = 0.54, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 102 TKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 K + + F D D G +S ++ + + G T L + D G++++++ Sbjct: 8 EKAKYDEIFLKTDKDMDGFVSGLEVREIFLKTGLPSTL--LAHIWSLCDTKDCGKLSKDQ 65 Query: 162 F 162 F Sbjct: 66 F 66 >5KU1-A nrPDB Length = 424 Score = 33.4 bits (75), Expect = 0.056, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 55/150 (36%), Gaps = 13/150 (8%) Query: 30 KQEVREAFDLFDSDGSGTIDVKEL----KVAMRALGFEPRKEEMKKMISEVDKEA--TGK 83 + + F + D D GT++ EL ++ E++K ++ + + Sbjct: 10 IKALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSG 69 Query: 84 ISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE-- 141 ++ FL + ++ E R F D+ ++ + L + + T+ Sbjct: 70 LTLKGFL-FLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHH 128 Query: 142 ----LQEMIDEADRDGDGEVNEEEFLKIMK 167 LQ D+ D D D ++ +E + K Sbjct: 129 AYLFLQSTFDKHDLDRDCALSPDELKDLFK 158 Score = 31.5 bits (70), Expect = 0.21, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 24/59 (40%), Gaps = 3/59 (5%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLA 91 ++ FD D D + ELK + + P ++ + V G I++ FL+ Sbjct: 133 LQSTFDKHDLDRDCALSPDELKDLFKVFPYIPWGPDVN---NTVCTNERGWITYQGFLS 188 >3A8R-A nrPDB Length = 179 Score = 33.0 bits (74), Expect = 0.061, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 34/82 (41%), Gaps = 8/82 (9%) Query: 31 QEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKK--------MISEVDKEATG 82 +R FD+ D + G + +E+K + + ++K+ ++ E+D G Sbjct: 98 NRLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKERADEYTALIMEELDPTNLG 157 Query: 83 KISFNDFLAVMTQKMAEKDTKE 104 I D A++ Q +E + Sbjct: 158 YIEMEDLEALLLQSPSEAAARS 179 Score = 31.1 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 9/85 (10%), Positives = 36/85 (42%), Gaps = 8/85 (9%) Query: 93 MTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQE-------- 144 +++ ++ + F + D + G+++ + +K + + +++E Sbjct: 87 FYEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKERADEYTAL 146 Query: 145 MIDEADRDGDGEVNEEEFLKIMKKT 169 +++E D G + E+ ++ ++ Sbjct: 147 IMEELDPTNLGYIEMEDLEALLLQS 171 Score = 27.2 bits (59), Expect = 3.3, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 22/47 (46%) Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 ++ LK +L + D L+ D D++ DG + EE +I+ Sbjct: 79 LTKDELKDFYEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIA 125 Score = 26.8 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 32/90 (35%), Gaps = 7/90 (7%) Query: 48 IDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT------QKMAEKD 101 + ELK L + ++ VDK A G+++ + ++ + K+ Sbjct: 79 LTKDELKDFYEQLTDQGFDNRLRTFFDMVDKNADGRLTAEEVKEIIALSASANKLSKIKE 138 Query: 102 TKEEILKAFR-LFDDDETGKISFKNLKRVA 130 +E D G I ++L+ + Sbjct: 139 RADEYTALIMEELDPTNLGYIEMEDLEALL 168 >4MSP-A nrPDB Length = 200 Score = 33.0 bits (74), Expect = 0.062, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 40/96 (41%), Gaps = 9/96 (9%) Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE--- 132 KE GKI + + + E ++F+ D ++ K+S +K + Sbjct: 100 YGKEGKGKIP-PESTLIFNIDLLEIRNGPRSHESFQEMDLNDDWKLSKDEVKAYLKKEFE 158 Query: 133 -----LGESLTDEELQEMIDEADRDGDGEVNEEEFL 163 + ES D ++++ D+ D D DG ++ EF Sbjct: 159 KHGAVVNESHHDALVEDIFDKEDEDKDGFISAREFT 194 Score = 31.1 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 10/63 (15%), Positives = 24/63 (38%), Gaps = 8/63 (12%) Query: 35 EAFDLFDSDGSGTIDVKELKVAMRA--------LGFEPRKEEMKKMISEVDKEATGKISF 86 E+F D + + E+K ++ + ++ + + D++ G IS Sbjct: 131 ESFQEMDLNDDWKLSKDEVKAYLKKEFEKHGAVVNESHHDALVEDIFDKEDEDKDGFISA 190 Query: 87 NDF 89 +F Sbjct: 191 REF 193 >6EAZ-A nrPDB Length = 379 Score = 33.0 bits (74), Expect = 0.066, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 34/87 (39%), Gaps = 6/87 (6%) Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN-ELGESLTDEE 141 IS ++F + E+ A ++F + KR G+ L+D Sbjct: 256 SISLDEFKSFC----HFTTHLEDFAIAMQMFSLAHR-PVRLAEFKRAVKVATGQELSDNL 310 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKK 168 L + D DGD ++ EFL ++K Sbjct: 311 LDTVFKIFDLDGDECLSHGEFLGVLKN 337 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 23/110 (20%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 AF + D DG+ I+ KE ++K+IS+ D T K + ++ + Sbjct: 124 AFKMLDVDGNEMIERKEFVK-------------LQKIISKQDGFKTVKTNETEYQDPTVK 170 Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEM 145 + T + R F K+ +K +R L E+QEM Sbjct: 171 EPGVNTTLQ-----VRFFGKRGEKKLHYKEFRRFMENL-----QTEVQEM 210 >2SAS-A nrPDB Length = 185 Score = 33.0 bits (74), Expect = 0.066, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 42/87 (48%), Gaps = 8/87 (9%) Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEEL 142 K +F+ FL + + + E+++ ++ G +S + K + L ++E Sbjct: 11 KFTFDFFLDMNHDGSIQDNDFEDMMTRYKEV---NKGSLSDADYKSMQASL-----EDEW 62 Query: 143 QEMIDEADRDGDGEVNEEEFLKIMKKT 169 +++ AD + D V+ EE+L + +KT Sbjct: 63 RDLKGRADINKDDVVSWEEYLAMWEKT 89 Score = 32.6 bits (73), Expect = 0.100, Method: Composition-based stats. Identities = 27/163 (16%), Positives = 53/163 (32%), Gaps = 44/163 (26%) Query: 25 LTEDQKQEVREAFDLF-DSDGSGTIDVKELKVAMR---------------ALGFEPRKEE 68 L + QKQ+++ FD F D + G+I + + M ++E Sbjct: 2 LNDFQKQKIKFTFDFFLDMNHDGSIQDNDFEDMMTRYKEVNKGSLSDADYKSMQASLEDE 61 Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKR 128 + + D +S+ ++LA+ + +A + + Sbjct: 62 WRDLKGRADINKDDVVSWEEYLAMWEKTIATCKSVAD----------------------- 98 Query: 129 VANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 ++ + + D GDG V+ EEF K L Sbjct: 99 -LPAWCQN----RIPFLFKGMDVSGDGIVDLEEFQNYCKNFQL 136 >2MHH-A nrPDB Length = 96 Score = 33.0 bits (74), Expect = 0.066, Method: Composition-based stats. Identities = 8/66 (12%), Positives = 29/66 (43%), Gaps = 2/66 (3%) Query: 27 EDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISF 86 D+ +++EA D++ +D E + ++ G +++ + ++ D + + Sbjct: 14 RDKIADIQEALAHADANADQHLDFDEWRQELKCRGHA--DADIEAVFAKYDVDGDRVLDA 71 Query: 87 NDFLAV 92 + + + Sbjct: 72 EEQMKM 77 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 14/72 (19%), Positives = 34/72 (47%), Gaps = 2/72 (2%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + +++D +I +A D + + F ++ G + D +++ + + D DG Sbjct: 8 SHMASKRDKIADIQEALAHADANADQHLDFDEWRQELKCRGHA--DADIEAVFAKYDVDG 65 Query: 154 DGEVNEEEFLKI 165 D ++ EE +K+ Sbjct: 66 DRVLDAEEQMKM 77 Score = 28.4 bits (62), Expect = 1.5, Method: Composition-based stats. Identities = 10/73 (13%), Positives = 30/73 (41%), Gaps = 3/73 (4%) Query: 67 EEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNL 126 ++++ ++ D A + F+++ + +I F +D D + + Sbjct: 18 ADIQEALAHADANADQHLDFDEWR---QELKCRGHADADIEAVFAKYDVDGDRVLDAEEQ 74 Query: 127 KRVANELGESLTD 139 ++A++L +D Sbjct: 75 MKMAHDLEGQKSD 87 >2WCE-A nrPDB Length = 95 Score = 33.0 bits (74), Expect = 0.073, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 25/55 (45%) Query: 113 FDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 FD G++ K +AN + + E+ D + D +V+ +EF+ ++ Sbjct: 28 FDTLSKGELKQLLTKELANTIKNIKDKAVIDEIFQGLDANQDEQVDFQEFISMVA 82 Score = 27.6 bits (60), Expect = 2.9, Method: Composition-based stats. Identities = 10/59 (16%), Positives = 26/59 (44%), Gaps = 6/59 (10%) Query: 39 LFDSDGSGTID---VKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 FD+ G + KEL ++ + K + ++ +D ++ F +F++++ Sbjct: 27 HFDTLSKGELKQLLTKELANTIKNI---KDKAVIDEIFQGLDANQDEQVDFQEFISMVA 82 >1B4A-A nrPDB Length = 149 Score = 32.6 bits (73), Expect = 0.078, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 38/102 (37%), Gaps = 7/102 (6%) Query: 49 DVKELKVAMRALGFEPRKEEMKKMISEVD----KEATGKISFNDFLAVMTQKMAEKDTKE 104 EL +R GF + + + I E+ A G+ ++ L + + K Sbjct: 21 TQDELVDRLREAGFNVTQATVSRDIKEMQLVKVPMANGRYKYS--LPSDQRFNPLQKLKR 78 Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMI 146 ++ F D + + L A+ +G L + + E++ Sbjct: 79 ALVDVFIKLDGTGN-LLVLRTLPGNAHAIGVLLDNLDWDEIV 119 >4HRG-A nrPDB Length = 115 Score = 32.6 bits (73), Expect = 0.083, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 34/83 (40%), Gaps = 6/83 (7%) Query: 94 TQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE-----LGESLTDEELQEMIDE 148 + + E ++ F F D G ++ ++L+ + + L + +++ + Sbjct: 1 SMPSQMEHAMETMMFTFHKFAGD-KGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKD 59 Query: 149 ADRDGDGEVNEEEFLKIMKKTNL 171 D+ DG+V + F ++ + Sbjct: 60 LDQCRDGKVGFQSFFSLIAGLTI 82 >4NSC-A nrPDB Length = 401 Score = 32.2 bits (72), Expect = 0.10, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 44/135 (32%), Gaps = 25/135 (18%) Query: 32 EVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLA 91 AF +FD +G G +D++E E+++ +I Sbjct: 147 NFEIAFKMFDLNGDGEVDMEEF-------------EQVQSIIRSQTSMGMRHRDRPT--- 190 Query: 92 VMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADR 151 T + + F F D GK++ KN +L + E + Sbjct: 191 --TGNTLKSGLCSALTTYF--FGADLKGKLTIKNFLEFQRKLQHDVLKLEFER-----HD 241 Query: 152 DGDGEVNEEEFLKIM 166 DG + E +F ++ Sbjct: 242 PVDGRITERQFGGML 256 Score = 30.7 bits (68), Expect = 0.37, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 46/129 (35%), Gaps = 13/129 (10%) Query: 45 SGTIDVKELKVAMRALG--FEPRKEEMKKMISEVDKEATGKI--SFNDFLAVMTQKMAEK 100 G I ++ + A + M++ + + KE G +F + Sbjct: 244 DGRITERQFGGMLLAYSGVQSKKLTAMQRQLKKHFKEGKGLTFQEVENFFTFLKNINDVD 303 Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELG-ESLTDEELQEMIDEADRDGDGEVNE 159 A D +++VA + L+D + D DG+GE++ Sbjct: 304 TALSFYHMAGASLDK--------VTMQQVARTVAKVELSDHVCDVVFALFDCDGNGELSN 355 Query: 160 EEFLKIMKK 168 +EF+ IMK+ Sbjct: 356 KEFVSIMKQ 364 Score = 26.8 bits (58), Expect = 5.1, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 13/24 (54%) Query: 36 AFDLFDSDGSGTIDVKELKVAMRA 59 F LFD DG+G + KE M+ Sbjct: 341 VFALFDCDGNGELSNKEFVSIMKQ 364 >3NSO-A nrPDB Length = 101 Score = 32.2 bits (72), Expect = 0.12, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 25/58 (43%), Gaps = 5/58 (8%) Query: 120 KISFKNLKRVANELGESLTDEELQE-----MIDEADRDGDGEVNEEEFLKIMKKTNLY 172 K+ LK + + + T E +E + D + D EV+ E+++ + LY Sbjct: 28 KLCQAELKELLQKELATWTPTEFRECDYNKFMSVLDTNKDCEVDFVEYVRSLACLCLY 85 >3JC6-4 nrPDB Length = 933 Score = 31.9 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 16/110 (14%), Positives = 51/110 (46%), Gaps = 1/110 (0%) Query: 10 VASTSYKRKVGPKPELTEDQKQEVREAFDLFDSD-GSGTIDVKELKVAMRALGFEPRKEE 68 A K K + E ++ + +R A + +D +G ID+ ++ + + +++ Sbjct: 806 EAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDL 865 Query: 69 MKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDET 118 +++++ + +A+ +SFN+ + + + ++ +I +A ++ Sbjct: 866 SREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQEDK 915 >6AGH-A nrPDB Length = 339 Score = 31.9 bits (71), Expect = 0.14, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 57/165 (34%), Gaps = 11/165 (6%) Query: 5 FRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEP 64 F K YK L + + QE+ F F S G + ++ + Sbjct: 180 FGKRGQRKLHYKEFRRFMENL-QTEIQEME--FLQF-SKGLSFMRKEDFAEWL-LFFTNT 234 Query: 65 RKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFK 124 +++ A IS ++F + E+ A ++F + Sbjct: 235 ENKDIYWKNVREKLSAGESISLDEFKSFC----HFTTHLEDFAIAMQMFSLAHR-PVRLA 289 Query: 125 NLKRVAN-ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKK 168 KR G+ L++ L + D DGD ++ EEFL ++K Sbjct: 290 EFKRAVKVATGQELSNNILDTVFKIFDLDGDECLSHEEFLGVLKN 334 Score = 28.0 bits (61), Expect = 1.9, Method: Composition-based stats. Identities = 18/113 (15%), Positives = 43/113 (38%), Gaps = 22/113 (19%) Query: 77 DKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKN---LKRVANEL 133 D G IS+ ++L ++T AF++ D D I + L+++ ++ Sbjct: 92 DLGDKGLISYTEYLFLLT---ILTKPHSGFHVAFKMLDTDGNEMIEKREFFKLQKIISKQ 148 Query: 134 GESLT--------------DEELQEM--IDEADRDGDGEVNEEEFLKIMKKTN 170 + +T + E+ + + G +++ +EF + M+ Sbjct: 149 DDLMTVKTNETGYQEAIVKEPEINTTLQMRFFGKRGQRKLHYKEFRRFMENLQ 201 >4MN0-A nrPDB Length = 208 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 24/59 (40%), Gaps = 4/59 (6%) Query: 17 RKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKE---LKVAMRALGFEPRKEEMKKM 72 + +L + + FD FD D G +++ E MR L E+++KM Sbjct: 22 QWQFNVEDLHPKMLSRLYKRFDTFDLDSDGKMEMDEVLYWPDRMRQL-VNATDEQVEKM 79 >4FTG-A nrPDB Length = 96 Score = 31.9 bits (71), Expect = 0.16, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 33/81 (40%), Gaps = 6/81 (7%) Query: 96 KMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE-----LGESLTDEELQEMIDEAD 150 + E ++ F F D G ++ ++L+ + + L + +++ + D Sbjct: 1 PSQMEHAMETMMFTFHKFAGD-KGYLTKEDLRVLMEKEFPGFLENQKDPLAVDKIMKDLD 59 Query: 151 RDGDGEVNEEEFLKIMKKTNL 171 + DG+V + F ++ + Sbjct: 60 QCRDGKVGFQSFFSLIAGLTI 80 >5CJ9-A nrPDB Length = 146 Score = 31.9 bits (71), Expect = 0.17, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 48/132 (36%), Gaps = 17/132 (12%) Query: 49 DVKELKVAMRALGFEPRKEEMKKMISEVD----KEATGKISFNDFLAVMTQKMAEKDTKE 104 EL ++A G+ + + + I E+ G+ ++ L + + K Sbjct: 18 TQDELVEQLKAAGYNVTQATVSRDIKELHLVKVPMMDGRYKYS--LPADQRFNPLQKLKR 75 Query: 105 EILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDG----------D 154 ++ +F D I K L A+ +G + + + E++ D D Sbjct: 76 GLVDSFVSIDR-TDNLIVMKTLPGNAHAIGALIDNLDWTEIMGTICGDDTILIICKDKQD 134 Query: 155 GEVNEEEFLKIM 166 G V E FL ++ Sbjct: 135 GPVVTERFLNML 146 >5CSF-A nrPDB Length = 95 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 27/56 (48%), Gaps = 5/56 (8%) Query: 117 ETGKISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 + K+ LK + N L E E + ++++ D DGDGE + +EF+ + Sbjct: 27 DKHKLKKSELKELINNELSHFLEEIKEQEVVDKVMETLDNDGDGECDFQEFMAFVA 82 >2KLD-A nrPDB Length = 123 Score = 31.5 bits (70), Expect = 0.18, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 GK++F L++ G TD E++ + + D+DGD E+ E E ++ Sbjct: 59 GGGKLNFDELRQDLKGKGH--TDAEIEAIFTKYDQDGDQELTEHEHQQM 105 Score = 26.5 bits (57), Expect = 6.9, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 73 ISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANE 132 ISE ++ GK++F++ + + T EI F +D D +++ +++ ++ Sbjct: 52 ISESLRQGGGKLNFDE---LRQDLKGKGHTDAEIEAIFTKYDQDGDQELTEHEHQQMRDD 108 Query: 133 LGESLTDEELQ 143 L + D +L Sbjct: 109 LEKEREDLDLD 119 Score = 25.7 bits (55), Expect = 9.4, Method: Composition-based stats. Identities = 7/44 (15%), Positives = 22/44 (50%), Gaps = 2/44 (4%) Query: 42 SDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKIS 85 G G ++ EL+ ++ G E++ + ++ D++ +++ Sbjct: 57 RQGGGKLNFDELRQDLKGKGH--TDAEIEAIFTKYDQDGDQELT 98 >5LPU-C nrPDB Length = 104 Score = 31.5 bits (70), Expect = 0.19, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 120 KISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 K++ LK + LG+ + Q+++ D + D EV+ +E+ + Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLS 83 >2KHN-A nrPDB Length = 121 Score = 31.5 bits (70), Expect = 0.19, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 +G I+ + + G L L ++ AD + DG +++ EF MK Sbjct: 46 SGFITGDQARNFFFQSG--LPQPVLAQIWALADMNNDGRMDQVEFSIAMK 93 >5NRM-B nrPDB Length = 66 Score = 31.5 bits (70), Expect = 0.22, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 24/52 (46%) Query: 114 DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 D D G I+ + + N L +L D ++ I D +GD +N +F + Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSININDFAIM 55 Score = 26.1 bits (56), Expect = 7.6, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 21/52 (40%) Query: 41 DSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAV 92 D DG+G+I+ + + L + + I D I+ NDF + Sbjct: 4 DVDGNGSINSIDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSININDFAIM 55 >2MJW-B nrPDB Length = 94 Score = 31.1 bits (69), Expect = 0.23, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 24/53 (45%), Gaps = 5/53 (9%) Query: 120 KISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 ++ LK + + L + + +++ + D +GD +V+ EF+ + Sbjct: 27 TLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVA 79 Score = 28.8 bits (63), Expect = 1.4, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 25/53 (47%), Gaps = 5/53 (9%) Query: 47 TIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 T+ ELKV M L K+ + K++ ++D ++ F++F+ + Sbjct: 27 TLTKGELKVLMEKELPGFLQSGKDKDAVDKLLKDLDANGDAQVDFSEFIVFVA 79 >5HYD-A nrPDB Length = 99 Score = 31.1 bits (69), Expect = 0.25, Method: Composition-based stats. Identities = 16/80 (20%), Positives = 37/80 (46%), Gaps = 7/80 (8%) Query: 95 QKMAEKDTKEEILKAFRLFDDDETG--KISFKNLKRVA-NELGESLTDEE----LQEMID 147 + + +++ F + E K+S LK + EL E L+ ++ + +++ Sbjct: 1 MPTQLEMAMDTMIRIFHRYSGKERKRFKLSKGELKLLLQRELTEFLSCQKETQLVDKIVQ 60 Query: 148 EADRDGDGEVNEEEFLKIMK 167 + D + D EV+ EF+ ++ Sbjct: 61 DLDANKDNEVDFNEFVVMVA 80 Score = 27.2 bits (59), Expect = 3.6, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 26/53 (49%), Gaps = 5/53 (9%) Query: 47 TIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 + ELK+ ++ L + + + K++ ++D ++ FN+F+ ++ Sbjct: 28 KLSKGELKLLLQRELTEFLSCQKETQLVDKIVQDLDANKDNEVDFNEFVVMVA 80 >2L50-A nrPDB Length = 102 Score = 31.1 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 9/57 (15%), Positives = 24/57 (42%), Gaps = 5/57 (8%) Query: 118 TGKISFKNLKRVAN-----ELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKT 169 KIS + + + L ++ + ++I D + DG ++ +E+ ++ Sbjct: 29 KNKISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEYWTLIGGI 85 Score = 26.5 bits (57), Expect = 6.4, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 19/48 (39%), Gaps = 5/48 (10%) Query: 47 TIDVKELKVAM-RALGFEPRK----EEMKKMISEVDKEATGKISFNDF 89 I + + + L + K+I +D G+ISF+++ Sbjct: 31 KISKSSFREMLQKELNHMLSDTGNRKAADKLIQNLDANHDGRISFDEY 78 >5HLO-A nrPDB Length = 94 Score = 31.1 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 15/26 (57%) Query: 146 IDEADRDGDGEVNEEEFLKIMKKTNL 171 E D + DG VN +EFL ++ K + Sbjct: 56 FKELDINTDGAVNFQEFLILVIKMGV 81 >1XDL-A nrPDB Length = 365 Score = 31.1 bits (69), Expect = 0.28, Method: Composition-based stats. Identities = 23/112 (20%), Positives = 45/112 (40%), Gaps = 15/112 (13%) Query: 23 PELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATG 82 P LT++QK+E+ E ++G G + E ++ +G ++++ E +E Sbjct: 7 PALTQEQKKELSEIAQSIVANGKGILAADE---SVGTMGNR-----LQRIKVENTEENRR 58 Query: 83 KISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELG 134 + F + L + IL L+ D GK+ + + E G Sbjct: 59 Q--FREIL-FSVDSSINQSIGGVILFHETLYQKDSQGKL----FRNILKEKG 103 >4CFQ-A nrPDB Length = 91 Score = 31.1 bits (69), Expect = 0.29, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 25/57 (43%), Gaps = 5/57 (8%) Query: 120 KISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNL 171 K++ LK + LG+ + Q+++ D + D EV+ +E+ + + Sbjct: 31 KLNKSELKELLTRELPSFLGKRTDEAAFQKLMSNLDSNRDNEVDFQEYCVFLSSIAM 87 >4DUQ-A nrPDB Length = 98 Score = 30.7 bits (68), Expect = 0.31, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 29/53 (54%), Gaps = 5/53 (9%) Query: 120 KISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 K+S +K + ++ +GE + +E L++++ D + D +V+ +E+ + Sbjct: 29 KLSKGEMKELLHKELPSFVGEKVDEEGLKKLMGSLDENSDQQVDFQEYAVFLA 81 >2JXC-A nrPDB Length = 100 Score = 30.3 bits (67), Expect = 0.40, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 26/57 (45%), Gaps = 4/57 (7%) Query: 112 LFDDDE--TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKIM 166 +FD G +S +K V L L + L + + +D D DG ++ +EF M Sbjct: 20 IFDSLSPVNGFLSGDKVKPVL--LNSKLPVDILGRVWELSDIDHDGMLDRDEFAVAM 74 >6DS2-B nrPDB Length = 114 Score = 30.3 bits (67), Expect = 0.41, Method: Composition-based stats. Identities = 14/88 (15%), Positives = 40/88 (45%), Gaps = 12/88 (13%) Query: 92 VMTQKMAEKDTKEEILKAFRLF-------DDDETGKIS---FKNLKRVANELGESLTDEE 141 + ++ + E I+ F + D G+ K+L+ + E+ ++ Sbjct: 1 MTSKMSQLERNIETIINTFHQYSVKLGHPDTLNQGEFKELVRKDLQNFLKK--ENKNEKV 58 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKT 169 ++ ++++ D + D +++ EEF+ +M + Sbjct: 59 IEHIMEDLDTNADKQLSFEEFIMLMARL 86 Score = 29.5 bits (65), Expect = 0.74, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Query: 50 VKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQ 95 K+L+ ++ ++ ++ ++ ++D A ++SF +F+ +M + Sbjct: 42 RKDLQNFLKK--ENKNEKVIEHIMEDLDTNADKQLSFEEFIMLMAR 85 >2KQ6-A nrPDB Length = 78 Score = 30.3 bits (67), Expect = 0.41, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 27/49 (55%), Gaps = 2/49 (4%) Query: 117 ETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 GK++F L++ G TD E++ + + D+DGD E+ E E ++ Sbjct: 13 GGGKLNFDELRQDLKGKGH--TDAEIEAIFTKYDQDGDQELTEHEHQQM 59 >1IQ3-A nrPDB Length = 110 Score = 30.3 bits (67), Expect = 0.42, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 27/65 (41%), Gaps = 2/65 (3%) Query: 100 KDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 ++ +E + FR D + IS K + L+ EL + + +D D DG + Sbjct: 18 EEQREYYVNQFRSLQPDPSSFISGSVAKNFFTK--SKLSIPELSYIWELSDADCDGALTL 75 Query: 160 EEFLK 164 EF Sbjct: 76 PEFCA 80 Score = 29.2 bits (64), Expect = 0.95, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 24/69 (34%), Gaps = 2/69 (2%) Query: 25 LTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKI 84 +TE+Q++ F D S I K + E+ + D + G + Sbjct: 16 ITEEQREYYVNQFRSLQPDPSSFISGSVAKNFFTK--SKLSIPELSYIWELSDADCDGAL 73 Query: 85 SFNDFLAVM 93 + +F A Sbjct: 74 TLPEFCAAF 82 >2Y5I-A nrPDB Length = 99 Score = 30.3 bits (67), Expect = 0.46, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 26/53 (49%), Gaps = 5/53 (9%) Query: 120 KISFKNLKRVANE-----LGESLTDEELQEMIDEADRDGDGEVNEEEFLKIMK 167 K+S LK + N L +++++++ D + D EV+ EF+ ++ Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVA 80 Score = 27.2 bits (59), Expect = 3.9, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 26/53 (49%), Gaps = 5/53 (9%) Query: 47 TIDVKELKVAMRA-----LGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMT 94 + ELK + A L + ++K+++++D ++ FN+F+ ++ Sbjct: 28 KLSKGELKELLNAELTDFLMSQKDPMLVEKIMNDLDSNKDNEVDFNEFVVLVA 80 >1SP9-A nrPDB Length = 445 Score = 29.9 bits (66), Expect = 0.51, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 36/72 (50%), Gaps = 7/72 (9%) Query: 13 TSYKRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKE-EMKK 71 + K++VG L++DQ +E E L D D GT+ L++ + LG P E+ + Sbjct: 344 QNLKKRVGDV--LSDDQIKECEELGILVDRDDQGTL----LQIFTKPLGDRPTIFIEIIQ 397 Query: 72 MISEVDKEATGK 83 + + K+ GK Sbjct: 398 RVGCMMKDEEGK 409 >1WLM-A nrPDB Length = 151 Score = 29.5 bits (65), Expect = 0.71, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 33/91 (36%), Gaps = 9/91 (9%) Query: 30 KQEVREAFDLFDSDGSGTIDVKEL---------KVAMRALGFEPRKEEMKKMISEVDKEA 80 + E+F F G +E+ K A G ++ + S+V ++ Sbjct: 14 IAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKAVTGTDVDIVFSKVKAKS 73 Query: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFR 111 I++ +F + + ++ + +AF Sbjct: 74 ARVINYEEFKKALEELATKRFKGKSKEEAFD 104 >2KFH-A nrPDB Length = 105 Score = 29.5 bits (65), Expect = 0.71, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 GKI+ N K+ + L + L ++ AD D DG +++EEF Sbjct: 30 NGKITGANAKK--EMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 72 >2JQ6-A nrPDB Length = 139 Score = 29.5 bits (65), Expect = 0.80, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 2/45 (4%) Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 GKI+ N K+ + L + L ++ AD D DG +++EEF Sbjct: 64 NGKITGANAKK--EMVKSKLPNTVLGKIWKLADVDKDGLLDDEEF 106 >6EFR-A nrPDB Length = 522 Score = 29.5 bits (65), Expect = 0.82, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 19/32 (59%) Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDG 153 LK V N+L ++DEE+Q++ + D +G Sbjct: 473 KHPELKDVLNKLANQISDEEMQKLNYKVDGEG 504 >5NRK-B nrPDB Length = 68 Score = 29.5 bits (65), Expect = 0.84, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 24/52 (46%) Query: 114 DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEFLKI 165 D D G I+ + + N L +L D ++ I D +GD +N +F + Sbjct: 4 DVDGNGSININDFALMRNYLLGNLKDFPAEDDIKAGDLNGDKSINSLDFAIM 55 >1FI6-A nrPDB Length = 92 Score = 29.5 bits (65), Expect = 0.84, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 25/64 (39%), Gaps = 2/64 (3%) Query: 101 DTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEE 160 + ++ + F+ D G I K + L EL + + +D D DG + + Sbjct: 6 EQRQYYVNQFKTIQPDLNGFIPGSAAKEFFTK--SKLPILELSHIWELSDFDKDGALTLD 63 Query: 161 EFLK 164 EF Sbjct: 64 EFCA 67 >5GAH-J nrPDB Length = 142 Score = 29.2 bits (64), Expect = 1.0, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%) Query: 115 DDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 D+ GKIS L+ +A +T +++ M Sbjct: 95 KDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSI 129 >4EMZ-A nrPDB Length = 266 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 30/91 (32%), Gaps = 14/91 (15%) Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 G I FL+ M + + K LFD+ GK L+ V L+ E Sbjct: 39 GSIKMRVFLSGMPELRLGLNDK-------VLFDNTGRGKSKSVELEDVKFHQCVRLSRFE 91 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 I DG EF + + N + Sbjct: 92 NDRTISFIPPDG-------EFELMSYRLNTH 115 >2QPT-A nrPDB Length = 550 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 GK+S K +G L + L + +D D DG +++EEF Sbjct: 471 DGKLSGSKAKTWM--VGTKLPNSVLGRIWKLSDVDRDGMLDDEEF 513 >2JRF-A nrPDB Length = 184 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 33/91 (36%), Gaps = 9/91 (9%) Query: 30 KQEVREAFDLFDSDGSGTIDVKEL---------KVAMRALGFEPRKEEMKKMISEVDKEA 80 + E+F F G +E+ K A G ++ + S+V ++ Sbjct: 7 IAGLEESFRKFAIHGDPKASGQEMNGKNWAKLCKDCKVADGKSVTGTDVDIVFSKVKGKS 66 Query: 81 TGKISFNDFLAVMTQKMAEKDTKEEILKAFR 111 I++ +F + + ++ + +AF Sbjct: 67 ARVINYEEFKKALEELATKRFKGKSKEEAFD 97 >3VSL-A nrPDB Length = 646 Score = 28.8 bits (63), Expect = 1.2, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 18/29 (62%), Gaps = 2/29 (6%) Query: 26 TEDQKQEVREAFDLF--DSDGSGTIDVKE 52 TE + ++++E F + D DG+G + K+ Sbjct: 537 TEKEIKQIQEGFKMAFNDKDGTGYVSFKD 565 >5DXI-A nrPDB Length = 302 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 121 ISFKNLKRVANELGESLTDEELQEMIDEADRDGDG 155 I + L LG+ LTDE++ ++E ++ G Sbjct: 219 IPIEELPDFMLCLGDDLTDEDMFNSLNEINKKWKG 253 >5R1R-A nrPDB Length = 761 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 17/42 (40%) Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNE 159 + + + N L E T+EE ++M D D D + Sbjct: 104 DHVVKMVEMGKYDNHLLEDYTEEEFKQMDTFIDHDRDMTFSY 145 >2KAY-A nrPDB Length = 92 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 29/53 (54%), Gaps = 7/53 (13%) Query: 120 KISFKNLKRVANE---LGESLTDEELQEMIDEADRDGDGEVNEEE---FLKIM 166 +S K LK + + LGE + + + +++ D++ D E++ +E FL ++ Sbjct: 28 TLSRKELKELIKKELCLGE-MKESSIDDLMKSLDKNSDQEIDFKEYSVFLTML 79 >4WSI-A nrPDB Length = 394 Score = 28.8 bits (63), Expect = 1.3, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 29/63 (46%), Gaps = 14/63 (22%) Query: 122 SFKNLKRVANELGESLTDEELQEMI---DEADRDGDGEVN-----------EEEFLKIMK 167 S + L+ + + G++ EEL+E+I E +++ + +E L+++ Sbjct: 320 SQERLRALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLIN 379 Query: 168 KTN 170 K + Sbjct: 380 KLD 382 >6BVD-A nrPDB Length = 436 Score = 28.4 bits (62), Expect = 1.6, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 106 ILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 ++K F+ + G+I + +K LG S T EE Sbjct: 93 MIKLFKRINSKPAGQILLEEIKNAIPYLGNSYTQEE 128 >2I7A-A nrPDB Length = 174 Score = 28.0 bits (61), Expect = 2.0, Method: Composition-based stats. Identities = 8/39 (20%), Positives = 22/39 (56%) Query: 134 GESLTDEELQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 G+ + +E + ++ + +G +++EEF ++ K+ Y Sbjct: 40 GDMFSLDECRSLVALMELKVNGRLDQEEFARLWKRLVHY 78 >6D84-M nrPDB Length = 423 Score = 28.0 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 30/91 (32%), Gaps = 14/91 (15%) Query: 82 GKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 G I FL+ M + + K LFD+ GK L+ V L+ E Sbjct: 196 GSIKMRVFLSGMPELRLGLNDK-------VLFDNTGRGKSKSVELEDVKFHQCVRLSRFE 248 Query: 142 LQEMIDEADRDGDGEVNEEEFLKIMKKTNLY 172 I DG EF + + N + Sbjct: 249 NDRTISFIPPDG-------EFELMSYRLNTH 272 >6BY1-CI nrPDB Length = 72 Score = 28.0 bits (61), Expect = 2.1, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%) Query: 115 DDETGKISFKNLKRVANELGESLTDEELQEMIDEA 149 D+ GKIS L+ +A +T +++ M Sbjct: 25 KDKVGKISRAQLQEIAQTKAADMTGADIEAMTRSI 59 >4QIW-A nrPDB Length = 906 Score = 27.6 bits (60), Expect = 2.5, Method: Composition-based stats. Identities = 7/29 (24%), Positives = 17/29 (58%), Gaps = 1/29 (3%) Query: 22 KPELTEDQKQEVREAFDLFDSDGSGTIDV 50 + +LT+++ +E + F++ D G +D Sbjct: 105 RIKLTDEEIEEYMQKFEVMG-DRKGAVDK 132 >3J09-A nrPDB Length = 723 Score = 27.6 bits (60), Expect = 3.2, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 20/33 (60%), Gaps = 3/33 (9%) Query: 109 AFRLFDDDETGKISFKNLKRVANELGESLTDEE 141 AF FD+ +I F+ +KRV +LG + DE+ Sbjct: 42 AFIRFDE---KRIDFETIKRVIEDLGYGVVDEQ 71 >6G18-t nrPDB Length = 475 Score = 27.2 bits (59), Expect = 3.5, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 31/86 (36%), Gaps = 5/86 (5%) Query: 41 DSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEK 100 D D +G + ++ M G + + ++ + ++ +VM + Sbjct: 203 DYDSAGLLSDED---CMSVPG--KTHRAIADHLFWSEETKSRFTEYSMTSSVMRRNEQLT 257 Query: 101 DTKEEILKAFRLFDDDETGKISFKNL 126 E K + +DDDE G + L Sbjct: 258 LHDERFEKFYEQYDDDEIGALDNAEL 283 >5MVF-A nrPDB Length = 523 Score = 26.8 bits (58), Expect = 4.2, Method: Composition-based stats. Identities = 17/45 (37%), Positives = 23/45 (51%), Gaps = 2/45 (4%) Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEEF 162 GKIS N K+ L + L ++ AD D DG ++EEEF Sbjct: 444 NGKISGVNAKKEMVT--SKLPNSVLGKIWKLADCDCDGMLDEEEF 486 >2DI4-A nrPDB Length = 238 Score = 26.8 bits (58), Expect = 4.2, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 5/84 (5%) Query: 66 KEEMKKMISEVDKEATGKIS-FNDFLAVMTQK--MAEKDTKEEILKAFRLFDDDETGKIS 122 EE+K++I+E ++A + + + L + +K E T EE ++ F+L+ + K Sbjct: 152 DEEVKRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKCK 211 Query: 123 FKNLKRVANELGES--LTDEELQE 144 + L + E+ L EE++E Sbjct: 212 KEELFDKDRKSEENKELKSEEVKE 235 >2Z61-A nrPDB Length = 370 Score = 26.8 bits (58), Expect = 4.7, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 33/81 (40%), Gaps = 6/81 (7%) Query: 75 EVDKEATGKI---SFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN 131 E D+ I F+ A+ ++ + +EI++A + IS + + A Sbjct: 206 EFDENLEKTILINGFSKLYAMTGWRIGYVISNDEIIEAILKLQQNL--FISAPTISQYAA 263 Query: 132 ELG-ESLTDEELQEMIDEADR 151 E T+ E+ MI E DR Sbjct: 264 LKAFEKETEREINSMIKEFDR 284 >1QJT-A nrPDB Length = 99 Score = 26.8 bits (58), Expect = 5.0, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 20/37 (54%) Query: 33 VREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEM 69 + + +DL D+DG G + +E VA+R + E+ Sbjct: 47 LGKIWDLADTDGKGVLSKQEFFVALRLVACAQNGLEV 83 >1SC5-A nrPDB Length = 239 Score = 26.8 bits (58), Expect = 5.2, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 35/92 (38%), Gaps = 17/92 (18%) Query: 58 RALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDE 117 LG EP EE+ K + +E + +F +++ + + FR F D Sbjct: 110 EKLGREPTDEEVAKELGISTEELFKTLDKINFSYILS-----------LEEVFRDFARD- 157 Query: 118 TGKISFKNLKRVANELGESLTDEELQEMIDEA 149 + L + + E + EL E + EA Sbjct: 158 -----YSELIPSSTNVEEEVIKRELTEKVKEA 184 >3J3U-A nrPDB Length = 810 Score = 26.8 bits (58), Expect = 5.4, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 44/96 (45%), Gaps = 4/96 (4%) Query: 48 IDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEI- 106 ID KV +R+ P +E+++ + EV KE + +F + + E+ +E++ Sbjct: 395 IDEAGSKVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVE 454 Query: 107 --LKAFRLFDDDETGKISFKNLKRVANEL-GESLTD 139 K+++ E +++ ++ V + G ++ Sbjct: 455 DTKKSWKEKQGQENSEVTVDDIAMVVSSWTGVPVSK 490 >3PXG-A nrPDB Length = 468 Score = 26.5 bits (57), Expect = 5.6, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 41/89 (46%), Gaps = 3/89 (3%) Query: 48 IDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEI- 106 ID KV +R+ P +E+++ + EV KE + +F + + E+ +E++ Sbjct: 378 IDEAGSKVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVE 437 Query: 107 --LKAFRLFDDDETGKISFKNLKRVANEL 133 K+++ E +++ ++ V + Sbjct: 438 DTKKSWKEKQGQENSEVTVDDIAMVVSSW 466 >5W62-A nrPDB Length = 192 Score = 26.5 bits (57), Expect = 6.3, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Query: 122 SFKNLKRVANELGESL-TDEELQEMIDEADRD 152 S K L +G+ L ++ ELQ MI + D D Sbjct: 55 STKKLSESLRRIGDELDSNMELQRMIADVDTD 86 >3PXI-A nrPDB Length = 758 Score = 26.5 bits (57), Expect = 6.5, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 44/96 (45%), Gaps = 4/96 (4%) Query: 48 IDVKELKVAMRALGFEPRKEEMKKMISEVDKEATGKISFNDFLAVMTQKMAEKDTKEEI- 106 ID KV +R+ P +E+++ + EV KE + +F + + E+ +E++ Sbjct: 378 IDEAGSKVRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQEFEKAASLRDTEQRLREQVE 437 Query: 107 --LKAFRLFDDDETGKISFKNLKRVANEL-GESLTD 139 K+++ E +++ ++ V + G ++ Sbjct: 438 DTKKSWKEKQGQENSEVTVDDIAMVVSSWTGVPVSK 473 >6FFL-A nrPDB Length = 388 Score = 26.5 bits (57), Expect = 6.6, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 18/35 (51%), Gaps = 2/35 (5%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDV 50 K+ + P+ +++ + ++ D++G G ID Sbjct: 122 KKFITTPPKNSQELIELGKK--MTVDTNGDGKIDR 154 >4JB3-A nrPDB Length = 228 Score = 26.1 bits (56), Expect = 7.3, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 22/44 (50%), Gaps = 5/44 (11%) Query: 112 LFDDDETGKISFKNLKRVANEL-GESLTDEELQE----MIDEAD 150 +F + E GK+S ++ +L G LT EE ++ +E D Sbjct: 67 IFQELEEGKLSADEFRKQLGDLCGRELTMEETKQAWLGFFNEVD 110 >4Z7E-A nrPDB Length = 293 Score = 26.1 bits (56), Expect = 7.6, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 20/32 (62%) Query: 122 SFKNLKRVANELGESLTDEELQEMIDEADRDG 153 + LK+ N+L +TD+E+++M E + +G Sbjct: 244 KYPELKKPLNKLAGKITDDEMRKMNYEVNVNG 275 >2V2V-A nrPDB Length = 271 Score = 26.1 bits (56), Expect = 7.9, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 17/27 (62%) Query: 126 LKRVANELGESLTDEELQEMIDEADRD 152 LK+V LG L++EEL+E++ D Sbjct: 107 LKKVNELLGSPLSEEELRELVGSISAD 133 >2GLF-A nrPDB Length = 450 Score = 26.1 bits (56), Expect = 8.0, Method: Composition-based stats. Identities = 16/104 (15%), Positives = 36/104 (34%), Gaps = 20/104 (19%) Query: 16 KRKVGPKPELTEDQKQEVREAFDLFDSDGSGTIDVKELKVAMRALGFEPRKEEMKKMISE 75 + +++ EAF + ++ +A +E+K+++ E Sbjct: 2 MERKNVWHHRKKEEI----EAF-----------SKEYMEFMSKAKTERMTVKEIKRILDE 46 Query: 76 VDKEATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETG 119 +G + DF + + + AFR+ DD + G Sbjct: 47 -----SGFVPLEDFAGDPMNMTVYAVNRGKAIAAFRVVDDLKRG 85 >4Z8X-A nrPDB Length = 497 Score = 26.1 bits (56), Expect = 8.4, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 33/64 (51%), Gaps = 3/64 (4%) Query: 66 KEEMKKMISEVDKEATGKIS-FNDFLAVMTQK--MAEKDTKEEILKAFRLFDDDETGKIS 122 EE++++I+E ++A + + + L + +K E T EE ++ F+L+ + K Sbjct: 411 DEEVRRIITEQYEKAKAIVEEYKEPLKAVVKKLLEKETITCEEFVEVFKLYGIELKDKCK 470 Query: 123 FKNL 126 + L Sbjct: 471 KEEL 474 >1QS1-A nrPDB Length = 462 Score = 26.1 bits (56), Expect = 8.4, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 18/44 (40%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDG 44 M + N T+YK ED+ ++++E +FD Sbjct: 94 MNNFLDNKNDIKTNYKEITFSMAGSFEDEIKDLKEIDKMFDKTN 137 >2Y3N-B nrPDB Length = 71 Score = 26.1 bits (56), Expect = 8.6, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 26/48 (54%), Gaps = 3/48 (6%) Query: 114 DDDETGKISFKNLKRVANELGESLTDEELQEMIDEADRDGDGEVNEEE 161 D + G I+ ++ +A G+++ + + E +AD + DG +N ++ Sbjct: 8 DLNGDGVINMADVMILAQSFGKAIGNPGVNE---KADLNNDGVINSDD 52 >1QS2-A nrPDB Length = 401 Score = 26.1 bits (56), Expect = 8.7, Method: Composition-based stats. Identities = 10/44 (22%), Positives = 18/44 (40%) Query: 1 MASTFRKSNVASTSYKRKVGPKPELTEDQKQEVREAFDLFDSDG 44 M + N T+YK ED+ ++++E +FD Sbjct: 33 MNNFLDNKNDIKTNYKEITFSMAGSFEDEIKDLKEIDKMFDKTN 76 >3NA5-A nrPDB Length = 570 Score = 25.7 bits (55), Expect = 9.6, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 33/81 (40%), Gaps = 2/81 (2%) Query: 79 EATGKISFNDFLAVMTQKMAEKDTKEEILKAFRLFDDDETGKISFKNLKRVAN--ELGES 136 A+G + D + + +A+ I KA D G + KR+A +L + Sbjct: 221 MASGHVKAVDLVQPFVEGLADIVDMAAIQKAGLTLGVDPLGGSGIEYWKRIAEHYKLNLT 280 Query: 137 LTDEELQEMIDEADRDGDGEV 157 L ++++ + D DG + Sbjct: 281 LVNDQVDQTFRFMHLDKDGAI 301 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.144 0.383 Lambda K H 0.267 0.0441 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 6,951,290 Number of Sequences: 36641 Number of extensions: 291227 Number of successful extensions: 4426 Number of sequences better than 10.0: 375 Number of HSP's better than 10.0 without gapping: 575 Number of HSP's successfully gapped in prelim test: 108 Number of HSP's that attempted gapping in prelim test: 1222 Number of HSP's gapped (non-prelim): 1649 length of query: 172 length of database: 10,336,785 effective HSP length: 90 effective length of query: 82 effective length of database: 7,039,095 effective search space: 577205790 effective search space used: 577205790 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.6 bits) S2: 56 (26.1 bits)