BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P40939 (763 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5ZRV-A nrPDB 1555 0.0 2D3T-A nrPDB 323 1e-88 4B3J-A nrPDB 317 8e-87 6IUM-B nrPDB 311 9e-85 2WTB-A nrPDB 306 2e-83 3ZWA-A nrPDB 274 1e-73 4PZE-A nrPDB 184 1e-46 3K6J-A nrPDB 177 1e-44 4KUG-A nrPDB 175 6e-44 1ZCJ-A nrPDB 171 1e-42 6ACQ-A nrPDB 169 5e-42 1F14-A nrPDB 159 6e-39 3HDH-A nrPDB 153 2e-37 6HRD-A nrPDB 152 4e-37 3MOG-A nrPDB 149 4e-36 4J0E-A nrPDB 149 6e-36 5Z7R-A nrPDB 127 2e-29 5ZAI-A nrPDB 121 1e-27 1ZEJ-A nrPDB 115 8e-26 4OM8-A nrPDB 115 8e-26 2PPY-A nrPDB 108 1e-23 2DUB-A nrPDB 103 4e-22 5JBW-A nrPDB 102 5e-22 3MOY-A nrPDB 102 6e-22 2HW5-A nrPDB 99 8e-21 5WYB-B nrPDB 98 2e-20 4FZW-A nrPDB 97 2e-20 3H81-A nrPDB 96 6e-20 4DYD-A nrPDB 89 8e-18 3HIN-A nrPDB 85 1e-16 4JWV-A nrPDB 80 4e-15 1XX4-A nrPDB 75 1e-13 5MRE-88 nrPDB 74 2e-13 5VE2-A nrPDB 74 3e-13 5YLO-A nrPDB 72 8e-13 4JCS-A nrPDB 70 4e-12 4IZC-A nrPDB 70 4e-12 3LAO-A nrPDB 66 6e-11 2VSU-C nrPDB 65 9e-11 5KJP-A nrPDB 65 2e-10 4JSB-A nrPDB 64 2e-10 3F3S-A nrPDB 62 7e-10 4FZW-C nrPDB 62 8e-10 1NZY-B nrPDB 62 8e-10 3M6N-A nrPDB 62 1e-09 3BPT-A nrPDB 61 2e-09 3OME-A nrPDB 60 4e-09 1EF9-A nrPDB 55 9e-08 3HE2-A nrPDB 53 6e-07 2A81-A nrPDB 52 9e-07 2IEX-A nrPDB 52 1e-06 4JFC-A nrPDB 49 7e-06 6OJM-A nrPDB 49 7e-06 3ADO-A nrPDB 49 1e-05 2UZF-A nrPDB 47 2e-05 3T88-A nrPDB 47 2e-05 4EML-A nrPDB 47 4e-05 4Q1J-A nrPDB 46 6e-05 4J2U-A nrPDB 45 9e-05 3T8B-A nrPDB 45 1e-04 2NP9-A nrPDB 45 1e-04 4HDT-A nrPDB 44 2e-04 3JU1-A nrPDB 42 0.001 3CTV-A nrPDB 41 0.002 3I47-A nrPDB 33 0.40 4KWB-A nrPDB 33 0.49 3RST-A nrPDB 33 0.52 6C25-A nrPDB 31 1.8 2BC1-A nrPDB 30 2.7 3GVH-A nrPDB 30 3.7 8ABP-A nrPDB 30 4.6 5XEF-A nrPDB 30 5.4 4C7U-A nrPDB 29 7.7 >5ZRV-A nrPDB Length = 763 Score = 1555 bits (4025), Expect = 0.0, Method: Compositional matrix adjust. Identities = 763/763 (100%), Positives = 763/763 (100%) Query: 1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK 60 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK Sbjct: 1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK 60 Query: 61 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLS 120 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLS Sbjct: 61 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLS 120 Query: 121 QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALP 180 QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALP Sbjct: 121 QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALP 180 Query: 181 GAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYL 240 GAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYL Sbjct: 181 GAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYL 240 Query: 241 EEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA 300 EEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA Sbjct: 241 EEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA 300 Query: 301 PLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD 360 PLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD Sbjct: 301 PLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD 360 Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF Sbjct: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP Sbjct: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK Sbjct: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA 600 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA Sbjct: 541 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA 600 Query: 601 EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK 660 EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK Sbjct: 601 EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK 660 Query: 661 LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF 720 LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF Sbjct: 661 LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF 720 Query: 721 VDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ 763 VDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ Sbjct: 721 VDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ 763 >2D3T-A nrPDB Length = 715 Score = 323 bits (829), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 242/713 (33%), Positives = 356/713 (49%), Gaps = 39/713 (5%) Query: 61 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTL--QEVTQ 118 VN ++ +E + ++ I A ++ V++SS FI GADI L E+ Sbjct: 29 VNKFNRLTLNELRQAVDAIKADASVKG-VIVSSGKDVFIVGADITEFVENFKLPDAELIA 87 Query: 119 LSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGA 178 + EA +I E P VAAING LGGGLE+ ++ +R+ K +G PEV LG Sbjct: 88 GNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAK--IGLPEVKLGI 145 Query: 179 LPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV--EPLGPGLKPPEERT 236 PG GGT RLP+++GV A++ + +G+ RA+ A K+ VD +V + LG +R Sbjct: 146 YPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDLIKRA 205 Query: 237 IEYLEEVAITFAKGLADKKI--SPKRDK---GLVEKLTAYAMTIPFVRQQVYKKVEEKVR 291 I G D K PK +K +E++ A+ FV Q Sbjct: 206 IS-----------GELDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAGQAGPN------ 248 Query: 292 KQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLY-HGQVLCK 350 YPAP++ I ++ G D E+ F +L T S L+GL+ + Q L K Sbjct: 249 ------YPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNCLIGLFLNDQELKK 302 Query: 351 KNK-FGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLN 409 K K + KDVK A+LGAG+MG GIA S KG ++KD +++G + K L Sbjct: 303 KAKVYDKIAKDVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIEQGLAEAAKLLV 362 Query: 410 DKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDH 469 +V K +T + + + + L Y F D+V+EAV E+ +K VL EVE + + Sbjct: 363 GRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKVKQAVLAEVENHVRED 422 Query: 470 CIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVG 529 I ASNTS + IS +A KRPE +GMH+F+PV M L+E+I EK+S A+ VA Sbjct: 423 AILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSSDLAVATTVAYA 482 Query: 530 LKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVD 589 K GK IVV D PGF R L P +++ GVD ++D + FG+P+G A L+D Sbjct: 483 KKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKFGWPMGPAYLMD 542 Query: 590 EVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLN 649 VG+D H + + + F +R + + LG+K+GKGFY Y+ K K Sbjct: 543 VVGIDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGKGFYAYEADKKGKQKK 602 Query: 650 SDMDSILASLK-LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGL 708 S+L LK + + +DEDI ++ E V CL++GI+ T AE D+G V+G+ Sbjct: 603 LVDSSVLEVLKPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGIVETAAEADMGLVYGI 662 Query: 709 GFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKF 761 GFP GG R++D G + V +Y A G + P L + A + F Sbjct: 663 GFPLFRGGALRYIDSIGVAEFVALADQY-AELGALYHPTAKLREMAKNGQSFF 714 >4B3J-A nrPDB Length = 736 Score = 317 bits (813), Expect = 8e-87, Method: Compositional matrix adjust. Identities = 237/728 (32%), Positives = 367/728 (50%), Gaps = 50/728 (6%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINML- 107 + + ++ P+ N +++ + ++ + A + V+++S F AG D+ + Sbjct: 31 IVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVKTMI 90 Query: 108 -AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRK 166 A + +V + +R + LE KP+VAAING+ LGGGLE+A++C +RIA + Sbjct: 91 QARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAADVKG 150 Query: 167 TVLGTPEVLLGALPGAGGTQRLPKMVGVPAA-LDMMLTGRSIRADRAKKMGLVDQLV--- 222 + LG PEV LG LPG GG R +M G+ A + ++ G + +AK++GLVD+LV Sbjct: 151 SQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELVATV 210 Query: 223 EPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQV 282 E L P K +++E G + P KG K+ + P + + Sbjct: 211 EELVPAAK-------AWIKEELKANPDGAG---VQPWDKKGY--KMPGGTPSSPGL-AAI 257 Query: 283 YKKVEEKVRKQTKGL-YPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMG 341 +RKQ KG PAP I+ G + D ES+ F LV + +K +M Sbjct: 258 LPSFPSNLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMMQ 317 Query: 342 LYHGQVLCKKNKFGAPQ----KDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTAL 397 + + P+ +K + +LGAG+MGAGIA VS G + +LKD +L A Sbjct: 318 AFFFDLQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAA 377 Query: 398 DRGQQQVFKGLNDKVKKKAL----TSFER-DSIFSNLTGQLDYQGFEKADMVIEAVFEDL 452 +G KG ++K++ KAL T+ ER D++ + +T D F+ D VIEAVFE+ Sbjct: 378 AKG-----KGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQ 432 Query: 453 SLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEII 512 LKH+V E+E ++ + I SNTS LPI+ +A KR E IG+H+FSPVDKM L+EII Sbjct: 433 ELKHKVFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEII 492 Query: 513 TTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLD 572 EKTS + A L GK IVV D GF+T+R + ++E + +L EGV+P ++ Sbjct: 493 KGEKTSDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIE 552 Query: 573 SLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPE----LLTQMVSKGFL 628 + G+P L DE+ +++ +A K + G P ++ +M+ G Sbjct: 553 QAGSQAGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRS 612 Query: 629 GRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMC 688 GR G GFY Y +G KR L + S P +D+ R++ E C Sbjct: 613 GRLKGAGFYEYADG-KRSGLWPGLRETFKSGSSQPPL-----QDMIDRMLFAEALETQKC 666 Query: 689 LQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLY------GAQKIVDRLKKYEAAYGK 742 L EG+L + A+ +IG++ G+GFPP GG +F+ Y G V R ++ AAYG Sbjct: 667 LDEGVLTSTADANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGD 726 Query: 743 QFTPCQLL 750 +F P + L Sbjct: 727 RFLPPESL 734 >6IUM-B nrPDB Length = 701 Score = 311 bits (796), Expect = 9e-85, Method: Compositional matrix adjust. Identities = 240/736 (32%), Positives = 363/736 (49%), Gaps = 68/736 (9%) Query: 43 YGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGA 102 Y V+ VAV+ +++P VN L E M D A++I+ F GA Sbjct: 5 YQVQDGVAVITLDNP--PVNGLGHSTRLGIVEGMTRAL-DDAAVKAIVITGAGKAFSGGA 61 Query: 103 DINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIAT 162 DI K +QE T S ++ LE S+KP+VAA++ +GGGLE+A+ C YR+A+ Sbjct: 62 DIREFNTPKAMQEPTLHS-----VIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRVAS 116 Query: 163 KDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 K + L PEV LG LPGAGGTQRLP+++G+ AA +M+++G + +++ L D++V Sbjct: 117 KGAQIAL--PEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIV 174 Query: 223 EPLGPGLKPPEERTIEYLEEVAITFAKGL-ADKKISPK-RD-KGLVEKLTAYAMTIPFVR 279 + G P A+ FA+ + A PK RD K E Y + F R Sbjct: 175 D----GDVLP----------AAVKFAQNVGAATGPHPKVRDLKVRHENPEGY---LGFAR 217 Query: 280 QQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKAL 339 V + +PAPLK ++ V G + + G E + F LV T ES+AL Sbjct: 218 NTVAAMAKN---------FPAPLKCLEAV-AGSLKPFEQGLKQEREGFLYLVTTPESRAL 267 Query: 340 MGLYHGQVLCKK---NKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 + G+ K G P + ++ +A++GAG MG GI+ ++ G+ + + A Sbjct: 268 RHAFFGERAASKIPDVPEGTPTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEA 327 Query: 397 LDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKH 456 LDRG + K + KK LT + + L+ L Y + AD++IEAVFE++ +K Sbjct: 328 LDRGVGIIRKNYENSAKKGKLTQEKVEQRMGLLSTTLSYDDLKDADLIIEAVFEEMGVKE 387 Query: 457 RVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEK 516 V K+++ V I ASNTS L +++IA+ +KRP+ V+GMH+FSP + M+LLE++ EK Sbjct: 388 TVFKKLDEVAKQGAILASNTSTLDVNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEK 447 Query: 517 TSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTT 576 T KD A+ + VG K K +V GF R + + +L EG P+++D Sbjct: 448 TGKDVLATVMQVGKKIKKTAVVSGVCDGFIGNRMIEQYSRQAGYLLDEGALPEQVDKAIE 507 Query: 577 SFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPE--------LLTQMVSKGFL 628 FGF +G + D G D+G +R PE LL +M G Sbjct: 508 KFGFAMGPFRMGDLAG--------NDIGWAIRKRRAVDKPEIQYSKTADLLCEM---GRF 556 Query: 629 GRKSGKGFYIYQEGVKRKDLNSDMDSILA--SLKLPPKSEVSSDEDIQFRLVTRFVNEAV 686 G+K+G G+Y Y+ G ++ N ++ ++ S L SDE+I RLV VNE Sbjct: 557 GQKTGAGWYDYKAGDRKPYPNQQVNDMIVQHSKDLGITRRKISDEEIVERLVFALVNEGA 616 Query: 687 MCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAY---GKQ 743 L+EGI + ++ D+ + G GFP GGP + D G + +K+Y Y Q Sbjct: 617 RILEEGIASKASDIDMVYLTGYGFPLFRGGPMLYADQVGLYNVALSMKRYAKGYHGEAWQ 676 Query: 744 FTP-CQLLADHANSPN 758 P Q LAD N Sbjct: 677 VAPLLQKLADEGKGFN 692 >2WTB-A nrPDB Length = 725 Score = 306 bits (785), Expect = 2e-83, Method: Compositional matrix adjust. Identities = 230/732 (31%), Positives = 358/732 (48%), Gaps = 44/732 (6%) Query: 38 RTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGC 97 +T + G G + IN P VN+LS ++ E + + ++ A++I+ G Sbjct: 8 KTVMEVGGDGVAVITLINPP---VNSLSFDVLYNLKSNYEEALSRNDVK-AIVITGAKGR 63 Query: 98 FIAGADINMLAACK--TLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAIS 155 F G DI+ + ++E I + LE + KP VAAI+G LGGGLE+A++ Sbjct: 64 FSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMA 123 Query: 156 CQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKM 215 C RI+ + LG PE+ LG +PG GGTQRLP++VG+ AL+M+LT + ++A+ + Sbjct: 124 CHARISAPAAQ--LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSL 181 Query: 216 GLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK---ISPKRDKGLVEKLTAYA 272 GL+D +V PP E L A +A + ++ +S + L Sbjct: 182 GLIDAVV--------PPAE-----LVTTARRWALDIVGRRKPWVSSVSKTDKLPPLGEAR 228 Query: 273 MTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVM 332 + F + Q K+ PL +D ++ GI G AG E++ ++V Sbjct: 229 EILTFAKAQTLKRAPN---------MKHPLMCLDAIEVGIVSGPRAGLEKEAEVASQVVK 279 Query: 333 TKESKALMGLYHGQVLCKK----NKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTI 388 +K L+ ++ Q K G + +K +AI+G GLMG+GIA + I Sbjct: 280 LDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILSNYPVI 339 Query: 389 LKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 LK+ L+ G +V L +V+K +++ + + S L G LDY+ F DMVIEAV Sbjct: 340 LKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDMVIEAV 399 Query: 449 FEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQL 508 E++SLK ++ ++E P HCI ASNTS + +++I +K ++++G H+FSP M L Sbjct: 400 IENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPAHIMPL 459 Query: 509 LEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDP 568 LEI+ T TS + VG K K +VV + GF R P + +++ G DP Sbjct: 460 LEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVECGADP 519 Query: 569 KKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFL 628 +D + FG P+G L D VG VA A + F ER ++ M Sbjct: 520 YLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSER--TYKSMIIPLMQEDKRA 577 Query: 629 GRKSGKGFYIYQEGVKRK---DLNSDMDSI--LASLKLPPKSEVSSDEDIQFRLVTRFVN 683 G + KGFY+Y + K K +L ++ ++ +KL PK S++DI VN Sbjct: 578 GEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTFFPVVN 637 Query: 684 EAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQ 743 EA EGI A+ DI + G+GFPP GG + D G++ I RL ++ AYG+ Sbjct: 638 EACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSKAYGEF 697 Query: 744 FTPCQLLADHAN 755 F PC LA+ + Sbjct: 698 FKPCAFLAERGS 709 >3ZWA-A nrPDB Length = 742 Score = 274 bits (700), Expect = 1e-73, Method: Compositional matrix adjust. Identities = 221/716 (30%), Positives = 354/716 (49%), Gaps = 71/716 (9%) Query: 48 DVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINML 107 +A++R+ +P VN +S + E + + SD A++I G F AGADI+ Sbjct: 30 SLAMIRLCNP--PVNAVSPTVIREVRNGLQKA-GSDHTVKAIVICGANGNFCAGADIHGF 86 Query: 108 AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKT 167 +A + L E QR KP++AAI G LGGGLE+A+ C YRIA + K Sbjct: 87 SAFTPGLALGSLVDEIQRY-------QKPVLAAIQGVALGGGLELALGCHYRIA--NAKA 137 Query: 168 VLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGP 227 +G PEV LG LPGA GTQ LP++VGVP ALD++ +G+ + AD A ++G++D +V+ Sbjct: 138 RVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKS--- 194 Query: 228 GLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQ--QVYKK 285 P EE AI FA+ + DK I P+R + +P + V+ + Sbjct: 195 --DPVEE---------AIKFAQKIIDKPIEPRR---------IFNKPVPSLPNMDSVFAE 234 Query: 286 VEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHG 345 KVRKQ G+ AP + ++ ++ + G E + F L + ++KAL + Sbjct: 235 AIAKVRKQYPGVL-APETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFA 293 Query: 346 QVLCKKNKFGAPQ---------KDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 + NK+ P + V + +LG G MG GIA G+ + ++ Sbjct: 294 EK--SANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQ 351 Query: 397 LDRGQQQVFKGLN---DKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLS 453 LD ++ + L + + S + FS+ T +L D+V+EAVFED++ Sbjct: 352 LDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELS-----TVDLVVEAVFEDMN 406 Query: 454 LKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIIT 513 LK +V E+ A+ +NTSAL + +IA+ + RP+ VIG H+FSP M+LLE+I Sbjct: 407 LKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIP 466 Query: 514 TEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDS 573 + +S T A+ +++ K GK+ +VV + GF R LAP ++ +L+EG P+ +D Sbjct: 467 SRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDG 526 Query: 574 LTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNP----------ELLTQMV 623 + FGF +G + D G+DV + + G + G G P L + Sbjct: 527 VLEEFGFKMGPFRVSDLAGLDVGWKIRKGQG-LTGPSLPPGTPVRKRGNSRYSPLGDMLC 585 Query: 624 SKGFLGRKSGKGFYIYQEGVKR-KDLNSDMDSILASLKLPPKSE--VSSDEDIQFRLVTR 680 G G+K+GKG+Y Y + + R + + + L+ + E S E+I R + Sbjct: 586 EAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYS 645 Query: 681 FVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKY 736 +NEA L+EG+ A P D+ + G G+P GGP + G ++++L+KY Sbjct: 646 LINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKY 701 >4PZE-A nrPDB Length = 284 Score = 184 bits (467), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 102/285 (35%), Positives = 169/285 (59%), Gaps = 7/285 (2%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 ++ + I+GAG MG GIAQ GL ++ D + A+ +G V L+ +KK+ LT Sbjct: 3 IRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 ++ S + + G Y + D+VIEA E+ LK ++LK+++ ++ ++ I ASNTS++ Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSIS 122 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 I+++AAV+ R ++ IGMH+F+PV M L+E+I +TS T A+ A+ + GK I VK Sbjct: 123 ITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGKYPITVK 182 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLDS-LTTSFGFPVGAATLVDEVGVDVAKH 598 + PGF R L PM++E +L EG+ P+++D + P+G L D +G+D Sbjct: 183 NSPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGMKLGCNHPIGPLALADMIGLDTMLA 242 Query: 599 VAEDLGKVFGE-RFGGGNPELLT-QMVSKGFLGRKSGKGFYIYQE 641 V E L F + ++ P +L +MV+ G+LGRK+G+G Y+Y + Sbjct: 243 VMEVLYTEFADPKY---RPAMLMREMVAAGYLGRKTGRGVYVYSK 284 >3K6J-A nrPDB Length = 460 Score = 177 bits (449), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 118/399 (29%), Positives = 202/399 (50%), Gaps = 38/399 (9%) Query: 360 DVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQV---------FKGLND 410 DV +AI+G G MG +A G++T L + R +Q++ FK LND Sbjct: 53 DVNSVAIIGGGTMGKAMAICFGLAGIETFL---VVRNEQRCKQELEVMYAREKSFKRLND 109 Query: 411 KVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHC 470 K +K I +NL D+ D+++E+V ED+ LK + +E + C Sbjct: 110 KRIEK---------INANLKITSDFHKLSNCDLIVESVIEDMKLKKELFANLENICKSTC 160 Query: 471 IFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGL 530 IF +NTS+L ++EI++V + P ++G+H+F+P + ++L+EII TS A+A Sbjct: 161 IFGTNTSSLDLNEISSVLRDPSNLVGIHFFNPANVIRLVEIIYGSHTSSQAIATAFQACE 220 Query: 531 KQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQE-GVDPKKLDSLTTSFGFPVGAATLVD 589 K+ ++V + F R L + +++ E G P ++D + T+FGF +G T+ D Sbjct: 221 SIKKLPVLVGNCKSFVFNRLLHVYFDQSQKLMYEYGYLPHQIDKIITNFGFLMGPMTVAD 280 Query: 590 EVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLN 649 G DV + + ++ G NP + +M GRK+ KGFY Y + +RK+ + Sbjct: 281 MNGFDVMEKLKKENGL-------EPNP-IEKEMWRLKRYGRKTNKGFYKYDDKTQRKEND 332 Query: 650 SDMDSILASLKLPPKSEVS--SDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFG 707 ++M+ I+ + KS + +D+D+ ++ VNE C++EG+++ + DI + G Sbjct: 333 TEMEQIIRRVSQNAKSNIQIINDQDVINFMLYPTVNEGYRCIEEGVISNESLIDIMFILG 392 Query: 708 LGFPPCLGGPFRFVDLYGAQKIVDRLKKY------EAAY 740 G+P GGP RF G KI + L + E+AY Sbjct: 393 FGWPIHSGGPMRFGKTEGLDKIANMLVHWSSLEPKESAY 431 >4KUG-A nrPDB Length = 290 Score = 175 bits (444), Expect = 6e-44, Method: Compositional matrix adjust. Identities = 102/284 (35%), Positives = 162/284 (57%), Gaps = 5/284 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 +K + +LGAG MGAGI Q KG + I++D +DRG + K L+ V K+ +T Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 +++ I S ++G D + D+V+EA E++ +K + E++ + I ASNTS+L Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILASNTSSLS 120 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 I+E+A+ +KR +KVIGMH+F+P M+L+E+I TS++T + + GK + V Sbjct: 121 ITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVA 180 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFG--FPVGAATLVDEVGVDVAKH 598 + PGF R L PM++E ILQEGV ++ G P+G L D +G+DV Sbjct: 181 EAPGFVVNRILIPMINEATFILQEGVAKEEDIDAAMKLGANHPMGPLALGDLIGLDVCLA 240 Query: 599 VAEDLGKVFGE-RFGGGNPELLTQMVSKGFLGRKSGKGFYIYQE 641 + + L G+ ++ + LL + V G+LGRK+GKGFY Y + Sbjct: 241 IMDVLYNETGDTKYRASS--LLRKYVRAGWLGRKTGKGFYDYSK 282 >1ZCJ-A nrPDB Length = 463 Score = 171 bits (433), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 119/397 (29%), Positives = 197/397 (49%), Gaps = 22/397 (5%) Query: 356 APQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLN---DKV 412 A + V + +LG G MG GIA G+ + ++ LD ++ + L + Sbjct: 32 ASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRA 91 Query: 413 KKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIF 472 + S + FS+ T +L D+V+EAVFED++LK +V E+ A+ Sbjct: 92 HQNGQASAKPKLRFSSSTKELS-----TVDLVVEAVFEDMNLKKKVFAELSALCKPGAFL 146 Query: 473 ASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQ 532 +NTSAL + +IA+ + RP+ VIG H+FSP M+LLE+I + +S T A+ +++ K Sbjct: 147 CTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKI 206 Query: 533 GKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVG 592 GK+ +VV + GF R LAP ++ +L+EG P+ +D + FGF +G + D G Sbjct: 207 GKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAG 266 Query: 593 VDVAKHVAEDLGKVFGERFGGGNP----------ELLTQMVSKGFLGRKSGKGFYIYQEG 642 +DV + + G + G G P L + G G+K+GKG+Y Y + Sbjct: 267 LDVGWKIRKGQG-LTGPSLPPGTPVRKRGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKP 325 Query: 643 VKR-KDLNSDMDSILASLKLPPKSE--VSSDEDIQFRLVTRFVNEAVMCLQEGILATPAE 699 + R + + + L+ + E S E+I R + +NEA L+EG+ A P Sbjct: 326 LGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYSLINEAFRILEEGMAARPEH 385 Query: 700 GDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKY 736 D+ + G G+P GGP + G ++++L+KY Sbjct: 386 IDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKY 422 >6ACQ-A nrPDB Length = 302 Score = 169 bits (427), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 100/284 (35%), Positives = 161/284 (56%), Gaps = 5/284 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 +K + ++GAG MG+GIAQ KG + +L+D +DRG + K L+ VKK + Sbjct: 21 MKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEA 80 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 + I + ++G +D D+VIEA E + +K ++ +++ + I ASNTS+L Sbjct: 81 TKVEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETILASNTSSLS 140 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 I+E+A+ +KRP+KVIGMH+F+P M+L+E+I TS++T + + GK + V Sbjct: 141 ITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIGKDPVEVA 200 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLD-SLTTSFGFPVGAATLVDEVGVDVAKH 598 + PGF R L PM++E + IL EG+ + +D ++ P+G L D +G+D+ Sbjct: 201 EAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGANHPMGPLELGDFIGLDICLA 260 Query: 599 VAEDLGKVFGERFGGGNPE-LLTQMVSKGFLGRKSGKGFYIYQE 641 + + L G+ P LL + V G+LGRKSGKGFY Y + Sbjct: 261 IMDVLYSETGD--SKYRPHTLLKKYVRAGWLGRKSGKGFYDYSK 302 >1F14-A nrPDB Length = 310 Score = 159 bits (401), Expect = 6e-39, Method: Compositional matrix adjust. Identities = 98/293 (33%), Positives = 155/293 (52%), Gaps = 18/293 (6%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 VKH+ ++G GLMGAGIAQV+ G +L D T L + + KG+ + ++K A F Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSK----KGIEESLRKVAKKKF 70 Query: 421 ERD---------SIFSNLTGQLDYQGF-EKADMVIEAVFEDLSLKHRVLKEVEAVIPDHC 470 + S + D D+V+EA+ E+L +K+ + K ++ +H Sbjct: 71 AENPKAGDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHT 130 Query: 471 IFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGL 530 IFASNTS+L I+ IA + R ++ G+H+F+PV M+L+E+I T TS+ T S V Sbjct: 131 IFASNTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSK 190 Query: 531 KQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLD---SLTTSFGFPVGAATL 587 GK + KD PGF R L P + E IR+ + G D K D ++ G+P+G L Sbjct: 191 ALGKHPVSCKDTPGFIVNRLLVPYLMEAIRLYERG-DASKEDIDTAMKLGAGYPMGPFEL 249 Query: 588 VDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQ 640 +D VG+D K + + ++ E L ++V++ G+K+G+GFY Y+ Sbjct: 250 LDYVGLDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 302 >3HDH-A nrPDB Length = 302 Score = 153 bits (387), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 94/289 (32%), Positives = 154/289 (53%), Gaps = 10/289 (3%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK----- 415 VKH+ ++G GLMGAGIAQV+ G +L D T L + ++ + + L KKK Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENP 74 Query: 416 -ALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 A F ++ S T D+V+EA+ E+L +K + K ++ +H IFAS Sbjct: 75 KAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHTIFAS 134 Query: 475 NTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGK 534 NTS+L I+ +A + R ++ G+H+F+PV M+L+E++ T TS+ T S V GK Sbjct: 135 NTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDFSKTLGK 194 Query: 535 VIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLD---SLTTSFGFPVGAATLVDEV 591 + KD PGF R L P + E +R+ + G D K D ++ G+P+G L+D V Sbjct: 195 HPVSCKDTPGFIVNRLLVPYLIEAVRLYERG-DASKEDIDTAMKLGAGYPMGPFELLDYV 253 Query: 592 GVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQ 640 G+D K + + ++ + + ++V++ G+K+G+GFY Y+ Sbjct: 254 GLDTTKFIIDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKYK 302 >6HRD-A nrPDB Length = 317 Score = 152 bits (385), Expect = 4e-37, Method: Compositional matrix adjust. Identities = 93/283 (32%), Positives = 154/283 (54%), Gaps = 5/283 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 ++ + ++GAG MG+GIA+VS G++ + + + G+ ++ K L V +T Sbjct: 25 IQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAVSAGKVTER 84 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPD-HCIFASNTSAL 479 ERD LT D +VIEAV ED ++K + E++ V+ D + ASNTS++ Sbjct: 85 ERDRALGLLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTDPDAVLASNTSSI 144 Query: 480 PISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLK-QGKVIIV 538 PI ++AA +K+P++V+G+H+F+PV + L+E++ T T + +A GK ++ Sbjct: 145 PIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFASTVLGKQVVR 204 Query: 539 VKDGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-SLTTSFGFPVGAATLVDEVGVDVA 596 D GF L P + IR+++ G + +D ++ P+G L D VG+D Sbjct: 205 CSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLSDLVGLDTL 264 Query: 597 KHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIY 639 K +A+ + + F E G P LL +MV G LG+KSG+GFY Y Sbjct: 265 KLIADKMFEEFKEPH-YGPPPLLLRMVEAGQLGKKSGRGFYTY 306 >3MOG-A nrPDB Length = 483 Score = 149 bits (377), Expect = 4e-36, Method: Compositional matrix adjust. Identities = 96/286 (33%), Positives = 148/286 (51%), Gaps = 8/286 (2%) Query: 360 DVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTS 419 +V+ +A++G+G MGAGIA+V+ G + +L D + AL R + LN +V + LT+ Sbjct: 4 NVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTA 63 Query: 420 FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSAL 479 + L D AD+VIEA E L +K + ++ V P + +NTS++ Sbjct: 64 ETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123 Query: 480 PISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVV 539 I+ IAA K PE+V G+H+F+P M+L+E+++ T+ + + L GK + Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRC 183 Query: 540 KDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLD-SLTTSFGFPVGAATLVDEVGVDVAK 597 PGF R P SE R L+E V P+ +D +L GFP+G L D +G DV Sbjct: 184 HSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNF 243 Query: 598 HVAEDLGKVFGE--RFGGGNPELLTQ-MVSKGFLGRKSGKGFYIYQ 640 V + F + RF P L+ Q +V G LG+KSG G Y ++ Sbjct: 244 AVTCSVFNAFWQERRF---LPSLVQQELVIGGRLGKKSGLGVYDWR 286 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 25/81 (30%), Positives = 42/81 (51%), Gaps = 5/81 (6%) Query: 675 FRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLK 734 +R V +NEA+ LQ+G+ A+ + D G+ +P GP + G Q+I+ L+ Sbjct: 391 WRTVAMIINEALDALQKGV-ASEQDIDTAMRLGVNYP---YGPLAWGAQLGWQRILRLLE 446 Query: 735 KYEAAYGKQ-FTPCQLLADHA 754 + YG++ + PC LL A Sbjct: 447 NLQHHYGEERYRPCSLLRQRA 467 Score = 36.2 bits (82), Expect = 0.055, Method: Compositional matrix adjust. Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Query: 431 GQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKR 490 G D++ +A + +EAV + S +V K+ + V + T +A R Sbjct: 281 GVYDWRAEREAVVGLEAVSDSFS-PMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLAR 339 Query: 491 PEKVIGMHYFSPVDKM--QLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTT 548 P VI DKM +++ I + A+ +QGK ++ + D PG Sbjct: 340 PVVVI--------DKMAGKVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGMLIW 391 Query: 549 RCLAPMMSEVIRILQEGVDPKK-LDS-LTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKV 606 R +A +++E + LQ+GV ++ +D+ + +P G ++G + E+L Sbjct: 392 RTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQHH 451 Query: 607 FGE 609 +GE Sbjct: 452 YGE 454 >4J0E-A nrPDB Length = 320 Score = 149 bits (375), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 89/292 (30%), Positives = 153/292 (52%), Gaps = 11/292 (3%) Query: 359 KDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALT 418 ++++++AI+G+G MG+GIAQV+ G +L D ALDR + + + + KK+ T Sbjct: 12 QNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGT 71 Query: 419 SFERDSIFSNLTGQLDY-----QGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFA 473 E+ + ++ AD++IEA E++ LK + ++E I Sbjct: 72 DKEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILT 131 Query: 474 SNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQG 533 +NTS+ + ++A + + G+H+F+PV M+LLE+I ++ TS +T A+ + G G Sbjct: 132 TNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVG 191 Query: 534 KVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLD---SLTTSFGFPVGAATLVDE 590 K + KD PGF R L P E R+ + G D D ++ G P+G L D Sbjct: 192 KTTVACKDSPGFIVNRLLIPYFFEAARMYERG-DASMTDIDEAMKLGAGHPMGPFELADY 250 Query: 591 VGVDVAKHVAEDLGKVFGE-RFGGGNPELLTQMVSKGFLGRKSGKGFYIYQE 641 +G+D K V + + E + +P L+ ++V++G LGRK+G GFY Y++ Sbjct: 251 IGLDTVKFVMDGWAAKYPEVQLFEASP-LVDKLVAEGKLGRKTGDGFYSYKK 301 >5Z7R-A nrPDB Length = 267 Score = 127 bits (319), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 70/179 (39%), Positives = 110/179 (61%), Gaps = 4/179 (2%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 +G VAVV IN P + +N L+ + E V+ EI ++ + +L + F+AGADI+ Sbjct: 11 EGKVAVVTINRPKA-LNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVAGADIS 69 Query: 106 MLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 + T+ E + ++ +LE KP++AA+NG LGGG E+A+SC RIA+ + Sbjct: 70 EMKEMNTI-EGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRIASSNA 128 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 + G PEV LG PG GGTQRL ++VG+ A ++ T ++I+AD A ++GLV+++VEP Sbjct: 129 R--FGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKVVEP 185 >5ZAI-A nrPDB Length = 259 Score = 121 bits (303), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 69/177 (38%), Positives = 111/177 (62%), Gaps = 5/177 (2%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 +G++ + +N P+ K+N L+ +L E +++ + +IR ++I+ K F AGADI Sbjct: 11 EGNLFWITLNRPD-KLNALNAKLLEELDRAVSQAESDPEIR-VIIITGKGKAFCAGADIT 68 Query: 106 MLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 T E + S++ + I++K+E +KP +A ING LGGGLE+A++C RIA ++ Sbjct: 69 QFNQL-TPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACDIRIAAEEA 127 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 + LG PE+ LG PG GGTQRL +++G AL+MM+TG I A+K GLV+++V Sbjct: 128 Q--LGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVNRVV 182 >1ZEJ-A nrPDB Length = 293 Score = 115 bits (288), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 95/294 (32%), Positives = 154/294 (52%), Gaps = 42/294 (14%) Query: 366 ILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSI 425 ++GAGLMG GIA +++ + +L+D + AL+ ++Q+ + L K++ T+ E+ Sbjct: 17 VIGAGLMGRGIA-IAIASKHEVVLQDVSEKALEAAREQIPEELLSKIE--FTTTLEK--- 70 Query: 426 FSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIA 485 + D+V+EAVFEDL+ K VL+EVE + + SNTS + + +IA Sbjct: 71 ------------VKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVISVDDIA 116 Query: 486 AVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGF 545 P + +G+H+ +P M L+EI+ + T T A + GK ++V K Sbjct: 117 ERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCKGQS-- 174 Query: 546 YTTRCLAPMMSEVIRILQEGVDPKKLDS--------LTTSFGFPVGAATLVDEVGVDVAK 597 R A ++SE R+++EGV + +D L T FG P+G +D +G+DVA Sbjct: 175 LVNRFNAAVLSEASRMIEEGVRAEDVDRVWKHHLGLLYTLFG-PLGN---LDYIGLDVAY 230 Query: 598 HVAEDLGKVFG-ERFGGGNPELLTQMVSKGFLGRKSGKGFY-----IYQEGVKR 645 + + L K FG E+F PE L + + KG +G K+GKG Y Y+E V+R Sbjct: 231 YASLYLYKRFGDEKF--KPPEWLQEKIKKGEVGVKAGKGIYEYGPKAYEERVER 282 >4OM8-A nrPDB Length = 309 Score = 115 bits (288), Expect = 8e-26, Method: Compositional matrix adjust. Identities = 86/292 (29%), Positives = 151/292 (51%), Gaps = 24/292 (8%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQ------QQVFKGLNDKVKK 414 ++++AI+G G MG G+A GL+ + D A++R + + V L + Sbjct: 2 IRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 415 KALTSFE-RDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFA 473 + + D I ++G AD+VIE V E++S+K V + ++ +I I A Sbjct: 62 AGVGTVRFTDDIGDAVSG---------ADLVIENVPENISIKADVYRTIDGLIGQDTIVA 112 Query: 474 SNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQG 533 S+TS +PI+++ A PE+++GMH+ +P + ++E+I EKT+ T A+ + G Sbjct: 113 SDTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIG 172 Query: 534 KVIIVV-KDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLDS-LTTSFGFP---VGAATL 587 + +VV KD PGF R L ++ E + +++ GV DP+ LD+ ++ G+ +G L Sbjct: 173 LLPVVVKKDVPGFVENRVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMAL 232 Query: 588 VDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIY 639 +D G+D+ K V+ L R P +L + + F G KSG+G + Y Sbjct: 233 LDMAGLDIYKSVSSFLNADLSNR-DDVAPMVLEKTSASKF-GIKSGEGMFCY 282 >2PPY-A nrPDB Length = 265 Score = 108 bits (269), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 66/207 (31%), Positives = 111/207 (53%), Gaps = 7/207 (3%) Query: 51 VVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAAC 110 + I+ +K N+ E + EF+ +++I I+ +++S P F AGADIN L + Sbjct: 19 IAEIHLHINKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADINFLRSA 78 Query: 111 KTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLG 170 + TQ ++K+ +S + +A + G +GGGLE+A++C R D +G Sbjct: 79 DP-RFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMALACDLRF-MGDEAGKIG 136 Query: 171 TPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLK 230 PEV LG L G GGTQRL +++G ALDM +TG +I A ++GLV+++ Sbjct: 137 LPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEIGLVNRVFPQ-----A 191 Query: 231 PPEERTIEYLEEVAITFAKGLADKKIS 257 ERT EY ++A + +++ K++ Sbjct: 192 ETRERTREYARKLANSATYAVSNIKLA 218 >2DUB-A nrPDB Length = 261 Score = 103 bits (256), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 67/184 (36%), Positives = 102/184 (55%), Gaps = 9/184 (4%) Query: 44 GVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD 103 G V ++++N P + +N L L E ++ + E + D A++++ F AGAD Sbjct: 13 GKNSSVGLIQLNRPKA-LNALCNGLIEELNQAL-ETFEEDPAVGAIVLTGGEKAFAAGAD 70 Query: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 I + +T Q+ S + + + + KP++AA+NG LGGG E+A+ C I Sbjct: 71 IKEMQN-RTFQDC--YSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCD--IIYA 125 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL-- 221 K G PE+LLG +PGAGGTQRL + VG A++M+LTG I A AK+ GLV ++ Sbjct: 126 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 185 Query: 222 VEPL 225 VE L Sbjct: 186 VETL 189 >5JBW-A nrPDB Length = 260 Score = 102 bits (255), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 63/176 (35%), Positives = 97/176 (55%), Gaps = 4/176 (2%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 +G + + I+ S+ N +S+ + E E++ + +S +R+ V+ + F AGAD+ Sbjct: 11 RGPIEIWTIDG-ESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLK 69 Query: 106 MLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 A EV +R +EKS +AAING+ LGGG E+A++C R+A Sbjct: 70 ERATMAE-DEVRAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAPAA 128 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL 221 + LG EV LG +PG GGTQRL ++VG A D++LT R I A A +GL ++L Sbjct: 129 E--LGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRL 182 >3MOY-A nrPDB Length = 263 Score = 102 bits (254), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 70/192 (36%), Positives = 106/192 (55%), Gaps = 8/192 (4%) Query: 31 GSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVL 90 GS T + V G V ++R++ P++ +N L++ L +E + + A +I A++ Sbjct: 3 GSMTTYTTIATSRPVAG-VGLIRLDRPDA-LNALNQTLEAEVLDAARDFDADLEI-GAIV 59 Query: 91 ISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGL 150 ++ F AGADI A TL + + L + KPIVAA+ G LGGG Sbjct: 60 VTGSERAFAAGADI---AEMVTLTPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGC 116 Query: 151 EVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRAD 210 E+A+ C IA + G PE+ LG LPG GGTQRL + VG A+D+ LTGRS+ A+ Sbjct: 117 ELAMLCDLVIAADTAR--FGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAE 174 Query: 211 RAKKMGLVDQLV 222 A+++GLV ++V Sbjct: 175 EAERVGLVSRIV 186 >2HW5-A nrPDB Length = 286 Score = 98.6 bits (244), Expect = 8e-21, Method: Compositional matrix adjust. Identities = 64/184 (34%), Positives = 100/184 (54%), Gaps = 9/184 (4%) Query: 44 GVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD 103 G V ++++N P + +N L L E ++ + +I+ D A++++ F AGAD Sbjct: 38 GKNNTVGLIQLNRPKA-LNALCDGLIDELNQAL-KIFEEDPAVGAIVLTGGDKAFAAGAD 95 Query: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 I + + L S + + + L + KP++AA+NG GGG E+A+ C I Sbjct: 96 IKEM---QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCD--IIYA 150 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL-- 221 K PE+L+G +PGAGGTQRL + VG A++M+LTG I A AK+ GLV ++ Sbjct: 151 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICP 210 Query: 222 VEPL 225 VE L Sbjct: 211 VETL 214 >5WYB-B nrPDB Length = 280 Score = 97.8 bits (242), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 65/200 (32%), Positives = 101/200 (50%), Gaps = 11/200 (5%) Query: 24 YICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASD 83 Y +F + L H G A++ IN P + NT ++ +++ + D Sbjct: 8 YKASSFDDTHKLTVEKH------GHTALITINHPPA--NTWDRDSLIGLRQLIEHLNRDD 59 Query: 84 QIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAING 143 I + V+ P F AGAD+NM A + ++++ E L +AAING Sbjct: 60 DIYALVVTGQGPKFFSAGADLNMFADGDKAR-AREMARRFGEAFEALRDFRGVSIAAING 118 Query: 144 SCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLT 203 +GGGLE A++C RIA +R+ + PE +G LP AGGTQ LP +VG A M+L Sbjct: 119 YAMGGGLECALACDIRIA--ERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILC 176 Query: 204 GRSIRADRAKKMGLVDQLVE 223 + A+ A ++GLV+Q+V+ Sbjct: 177 NERVDAETALRIGLVEQVVD 196 >4FZW-A nrPDB Length = 258 Score = 97.4 bits (241), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/203 (33%), Positives = 112/203 (55%), Gaps = 20/203 (9%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEI--WASDQIRSAVLISSKPGCFIAGADINM 106 V ++ +N P ++ N L+ L +++NE+ A+D S +I+ F AGAD+N Sbjct: 15 VLLLTLNRPAAR-NALNNAL---LMQLVNELEAAATDTSISVCVITGNARFFAAGADLNE 70 Query: 107 LAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRK 166 +A K L L+ ++ +L+ KP++AA+NG LG G E+A+ C +A ++ + Sbjct: 71 MAE-KDL--AATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENAR 127 Query: 167 TVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLG 226 G PE+ LG +PGAGGTQRL + VG A M+L+G SI A +A++ GLV + Sbjct: 128 --FGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVF---- 181 Query: 227 PGLKPPEERTIEYLEEVAITFAK 249 P + T+EY ++A A+ Sbjct: 182 -----PSDLTLEYALQLASKMAR 199 >3H81-A nrPDB Length = 278 Score = 95.9 bits (237), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 60/174 (34%), Positives = 94/174 (54%), Gaps = 7/174 (4%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLA 108 V ++ +N P + +N L+ ++ +E + E+ I A++I+ F AGADI +A Sbjct: 35 VGIITLNRPQA-LNALNSQVMNEVTSAATELDDDPDI-GAIIITGSAKAFAAGADIKEMA 92 Query: 109 ACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTV 168 L + + KL P +AA+ G LGGG E+A+ C IA K Sbjct: 93 ---DLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDVLIAADTAK-- 147 Query: 169 LGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 G PE+ LG LPG GG+QRL + +G A+D++LTGR++ A A++ GLV ++V Sbjct: 148 FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSRVV 201 >4DYD-A nrPDB Length = 283 Score = 88.6 bits (218), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 78/287 (27%), Positives = 133/287 (46%), Gaps = 15/287 (5%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++ +LG G++G+ IA + G D ALD +++ F+GL +K+ + Sbjct: 4 ITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKR-FEGLAAVYEKEVAGA- 61 Query: 421 ERDSIFSNLTGQLDY-----QGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASN 475 D G + Y Q + AD+VIEAV E L LK + ++ + P IFA+N Sbjct: 62 -ADGAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFATN 120 Query: 476 TSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKV 535 +S L S++ + R +K + +H+ + V E++ T KT + V G V Sbjct: 121 SSTLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAIGMV 180 Query: 536 IIVV-KDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLD-SLTTSFGFPVGAATLVDEVG 592 I + K+ G+ L P++ +L +G+ DP+ +D + G P G + D VG Sbjct: 181 PIELKKEKAGYVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGAPKGPFEIFDIVG 240 Query: 593 VDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIY 639 + A +++ V G + L + KG LG +G+GFY Y Sbjct: 241 LTTAYNIS----SVSGPKQREFAAYLKENYIDKGKLGLATGEGFYRY 283 >3HIN-A nrPDB Length = 275 Score = 84.7 bits (208), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 60/177 (33%), Positives = 89/177 (50%), Gaps = 7/177 (3%) Query: 47 GDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINM 106 G V + +N P K N L+ L + + + +I DQIR AV+I F AG D++ Sbjct: 24 GPVLTIGLNRPK-KRNALNDGLMAALKDCLTDI--PDQIR-AVVIHGIGDHFSAGLDLSE 79 Query: 107 LAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRK 166 L + + SQ R+ +K++ P++AA+ G+ +GGGLE+A + R+A Sbjct: 80 LRERDATEGLVH-SQTWHRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHIRVAEASAY 138 Query: 167 TVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVE 223 L PE G G GG+ RLP+++GV DMMLTGR A G L+E Sbjct: 139 YAL--PEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQYLIE 193 >4JWV-A nrPDB Length = 278 Score = 80.1 bits (196), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 55/184 (29%), Positives = 93/184 (50%), Gaps = 10/184 (5%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 I++ ++G VA VR+N P +N +++E+ + E+ A+ I + VL + F Sbjct: 26 IDFRIEGHVAHVRLNRPQG-LNAITQEMDDLLLDAWTEVNANSDIWAVVLSAEGEKAFCI 84 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKST--KPIVAAINGSCLGGGLEVAISCQY 158 GAD++ A KT +++ T KP+VAA+ G C+GGG E+A+ Sbjct: 85 GADVSGGAERKT-----RMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGGFELAMCADI 139 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV 218 +A + G PE +G + G R + + AL ++LTG I+AD A+ GLV Sbjct: 140 IVAADTAQ--FGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARHYGLV 197 Query: 219 DQLV 222 +++V Sbjct: 198 NEVV 201 >1XX4-A nrPDB Length = 261 Score = 75.1 bits (183), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 52/174 (29%), Positives = 84/174 (48%), Gaps = 3/174 (1%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLA 108 +AV++ +P VN+LS E +EF + ++ IR +L S +PG F AG D+ M Sbjct: 16 IAVMKFKNP--PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSAGLDL-MEM 72 Query: 109 ACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTV 168 + + + Q + +L S +++AING+ GG +A++C YRI + K Sbjct: 73 YGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRIMADNSKYT 132 Query: 169 LGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 +G E LLG + +G AA + G A K+GLVD++V Sbjct: 133 IGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVDEVV 186 >5MRE-88 nrPDB Length = 457 Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 91/189 (48%), Gaps = 12/189 (6%) Query: 43 YGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISS-KPGCFIAG 101 + V+ V+ +N P K+N L+ E+ + +NE SD +L SS +P F AG Sbjct: 6 FTVQDTARVITLNRP-KKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAG 64 Query: 102 ADINMLAAC---KTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQY 158 D+ +A K + + + + ++ KPIV ++G +GGG+ ++I + Sbjct: 65 GDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPF 124 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVP-----AALDMMLTGRSIRADRAK 213 RIAT++ K + PE+ +G P G T LP++V + AL + LTG + A Sbjct: 125 RIATENTKWAM--PEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAY 182 Query: 214 KMGLVDQLV 222 +GL V Sbjct: 183 MLGLASHYV 191 >5VE2-A nrPDB Length = 275 Score = 73.6 bits (179), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 56/183 (30%), Positives = 90/183 (49%), Gaps = 8/183 (4%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 +N + V + IN P K N L++EL++ ++ + DQIR AVL+++ F A Sbjct: 27 LNVSLNNRVLSLTINRPELK-NALNRELYAALADELERSNHDDQIR-AVLLTANGDTFTA 84 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 G D++ ++E S R ++ + + PIV A+NG +G GL + + C Sbjct: 85 GNDLDDF--INPVEESGTPS--VIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDMVY 140 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 A+K + P +G +P A + LP VG A D+ML GR + A A GLV + Sbjct: 141 ASKSAR--FRAPFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTR 198 Query: 221 LVE 223 + E Sbjct: 199 VFE 201 >5YLO-A nrPDB Length = 271 Score = 72.4 bits (176), Expect = 8e-13, Method: Compositional matrix adjust. Identities = 68/260 (26%), Positives = 111/260 (42%), Gaps = 40/260 (15%) Query: 45 VKGDVAVVRINSPNSKVNTLS----KELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 V+ +A + +N P + N L + LH D AV++ F A Sbjct: 11 VEAGIAWLVLNRPQQR-NALDIPTLEALHVRLDACER-----DPAVRAVVLGGSGRSFCA 64 Query: 101 GADINMLAACKTLQEVTQ--LSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQY 158 GAD+ AA + E+ ++ A ++ +L KP VAA+NGS +G G+++A+ C + Sbjct: 65 GADLAEWAAAEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDF 124 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV 218 RIA + G + P AG + LP+++G AA ++ + A+RA GLV Sbjct: 125 RIAAASARFKAGYTG--MAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLV 182 Query: 219 DQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFV 278 ++V E+L E FA LA A+A T + Sbjct: 183 GEVV-------------ADEHLVEAVGAFAARLASGPT------------FAFAQTKRLL 217 Query: 279 RQQVYKKVEEKVR-KQTKGL 297 R + + E++R +Q GL Sbjct: 218 RDGAGRSLAEQLRAEQAAGL 237 >4JCS-A nrPDB Length = 286 Score = 70.1 bits (170), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 64/271 (23%), Positives = 120/271 (44%), Gaps = 24/271 (8%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 +++ V +V +R+N +K N EL ++ V+ + IR VL +S PG F A Sbjct: 26 LDFEVVNNVGWIRMNRA-AKHNPFDAELRADLMTVLERVRDDADIRVLVL-TSHPGSFCA 83 Query: 101 GADINMLAACKTLQEVTQLSQE----AQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 G ++++L L Q+ R + + +P++AA++G G G ++++ Sbjct: 84 GGNLHVLR--DNLDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFALSLTA 141 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 +A+ + + LG +P G LP+ VG+ A ++M + R + A+ A ++G Sbjct: 142 DIVLASP--RARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLG 199 Query: 217 LVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK----ISPKRDKGLVEKLTAYA 272 LV ++ E + E+R E E + LA K +S D+ + L A + Sbjct: 200 LVMEVHES-----EALEQRAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLEAAS 254 Query: 273 MTIPFVRQQVYKKVEEKVRKQTKGLYPAPLK 303 F ++ +E + KQ P P + Sbjct: 255 QAAAFSTKEPRAAIEALLSKQ-----PPPFR 280 >4IZC-A nrPDB Length = 275 Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 54/180 (30%), Positives = 84/180 (46%), Gaps = 14/180 (7%) Query: 49 VAVVRINSPNSKVNTLS----KELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD- 103 V VV +N P+ K N L +EL + FS + +R AV+++ F AG D Sbjct: 21 VCVVTLNRPD-KRNALDVATIEELVTFFSTAHRK-----GVR-AVVLTGAGDHFCAGLDL 73 Query: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 + A ++ + + K+E PI+AA+ G+ +GGGL +A + R+ Sbjct: 74 VEHWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRV--M 131 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVE 223 D+ T PE G G G T R+ M+G +DM+LTGR + A +GL + E Sbjct: 132 DQSTYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITE 191 >3LAO-A nrPDB Length = 258 Score = 65.9 bits (159), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 57/187 (30%), Positives = 87/187 (46%), Gaps = 12/187 (6%) Query: 60 KVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAA--CKTLQEVT 117 K N + ++ + M E S++ R AVL + F AG D+ LA + Sbjct: 32 KRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGE-HFTAGLDLMELAPKLAASGFRYP 90 Query: 118 QLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLG 177 + +V+ + +KP+V A+ G+C G+E+ ++ IA R T EVL G Sbjct: 91 DGGVDPWGVVQP--RRSKPLVVAVQGTCWTAGIELMLNAD--IAVAARGTRFAHLEVLRG 146 Query: 178 ALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTI 237 P G T R P+ G A+ +LTG AD A +M L+ ++VEP G L R + Sbjct: 147 IPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTEVVEP-GEELA----RAL 201 Query: 238 EYLEEVA 244 EY E +A Sbjct: 202 EYAERIA 208 >2VSU-C nrPDB Length = 275 Score = 65.5 bits (158), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 58/217 (26%), Positives = 99/217 (45%), Gaps = 25/217 (11%) Query: 45 VKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADI 104 ++ +A V +N P K N +S L+ E +V+ + D ++++ + AG D+ Sbjct: 15 IEDGIAFVILNRP-EKRNAMSPTLNREMIDVLETL-EQDPAAGVLVLTGAGEAWTAGMDL 72 Query: 105 NML-----AACKTLQEVTQLSQEAQRIVEKLEK-STKPIVAAINGSCLGGGLEVAISCQY 158 A + LQE ++ +EA + KL + KP +A +NG C GGG ++C Sbjct: 73 KEYFREVDAGPEILQE--KIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLVACDL 130 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV 218 I + G E+ G PG ++ + VG +L ++TG++ +A +MGLV Sbjct: 131 AICADE--ATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLV 188 Query: 219 DQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK 255 ++ V PL L EV I A+ L +K Sbjct: 189 NESV-PLAQ------------LREVTIELARNLLEKN 212 >5KJP-A nrPDB Length = 265 Score = 64.7 bits (156), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 52/176 (29%), Positives = 93/176 (52%), Gaps = 10/176 (5%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLA 108 + ++ IN P +K N ++ + ++ M+++ D S +++ G F AG D+ A Sbjct: 25 ILIITINRPKAK-NAVNAAVSRGLADAMDQL-DGDAGLSVAILTGGGGSFCAGMDLKAFA 82 Query: 109 ACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTV 168 + + E + + TKP++AA+ G L GG E+A++ +A +D + Sbjct: 83 RGE------NVVVEGRGLGFTERPPTKPLIAAVEGYALAGGTELALAADLIVAARD--SA 134 Query: 169 LGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 G PEV G + G GG RLP+ + A+++ LTG ++ A+RA ++GLV+ L EP Sbjct: 135 FGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAERAHELGLVNVLAEP 190 >4JSB-A nrPDB Length = 296 Score = 63.9 bits (154), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 50/198 (25%), Positives = 98/198 (49%), Gaps = 22/198 (11%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + + G+VA + ++ P+ + N ++ + +E + + + + + +I V+I+ + F + Sbjct: 38 LTLTIDGEVARITLSRPHRR-NAMTGRMWTELARIGHTLPQAVRI---VVITGEGPTFSS 93 Query: 101 GADINMLAACKTLQEVT----------------QLSQEAQRIVEKLEKSTKPIVAAINGS 144 G D++M A K E T Q+ Q L ++ +AA+ G Sbjct: 94 GIDLDMFQAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIAAVRGH 153 Query: 145 CLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTG 204 +G G ++A+SC RI + + + P LG +P GTQ L ++VGV A+++ LT Sbjct: 154 AIGAGFQLALSCDIRILSDTAQLCMKEPA--LGLVPDLTGTQPLVELVGVNRAIELCLTA 211 Query: 205 RSIRADRAKKMGLVDQLV 222 R+I A A ++ L +++V Sbjct: 212 RTIDAAEAAQLRLAERVV 229 >3F3S-A nrPDB Length = 313 Score = 62.4 bits (150), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 60/220 (27%), Positives = 104/220 (47%), Gaps = 18/220 (8%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALT----- 418 + I+G+G++G A + G + L D QQQ+ L + K+ L Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIE-------QQQIRNALENIRKEMKLLEQAGS 58 Query: 419 ---SFERDSIFSNLTGQLDYQ-GFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 S + S ++G + Q E A + E V EDL LK ++ +++++I D I +S Sbjct: 59 LKGSLSVEEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSS 118 Query: 475 NTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGK 534 +TS L S++ A ++ I H +P + L+E++ +T+ T A+ K G+ Sbjct: 119 STSCLMPSKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQ 178 Query: 535 VII-VVKDGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD 572 + V K+ GF R ++SE R+++EG V P LD Sbjct: 179 CPMRVQKEVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLD 218 >4FZW-C nrPDB Length = 274 Score = 62.4 bits (150), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 96/189 (50%), Gaps = 13/189 (6%) Query: 39 THINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCF 98 +H+ GV + +N P ++N+ + E+H++ +E + ++ D IR +L + G F Sbjct: 19 SHVEKGV----MTLTLNRP-ERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRG-F 72 Query: 99 IAGADINMLAACKTLQEVTQLSQEAQR----IVEKLEKSTKPIVAAINGSCLGGGLEVAI 154 AG D+N T L +R +V +L K KP++ A+NG G G +A+ Sbjct: 73 CAGQDLNDRNVDPT-GPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLAL 131 Query: 155 SCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKK 214 IA + K V+ + LG +P GGT LP++ G A+ + L G + A++A + Sbjct: 132 GGDIVIAARSAKFVMAFSK--LGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHE 189 Query: 215 MGLVDQLVE 223 G++ Q+V+ Sbjct: 190 WGMIWQVVD 198 >1NZY-B nrPDB Length = 269 Score = 62.4 bits (150), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 49/185 (26%), Positives = 90/185 (48%), Gaps = 8/185 (4%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 I + V+ VA + I P + N LS + E ++ +N D + AV+I+ F A Sbjct: 5 IGHRVEDGVAEITIKLPRHR-NALSVKAMQEVTDALNRAEEDDSV-GAVMITGAEDAFCA 62 Query: 101 GADINMLAACKTLQEVTQLSQEA----QRIVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 G + + K + V + A +++ K+ + +P++AAING GGGL ++++ Sbjct: 63 GFYLREIPLDKGVAGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLAS 122 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 I K V + +G + L ++VG+ A+++MLT R++ + AK G Sbjct: 123 DMAICADSAKFVCAWHTIGIGN--DTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWG 180 Query: 217 LVDQL 221 LV ++ Sbjct: 181 LVSRV 185 >3M6N-A nrPDB Length = 305 Score = 61.6 bits (148), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 47/154 (30%), Positives = 75/154 (48%), Gaps = 13/154 (8%) Query: 89 VLISSKPGCFIAGADINMLAACKTLQE--VTQLSQEAQRIVEKLEK------STKPIVAA 140 V+++S F G D+ + C+ ++E +L AQR V + + +A Sbjct: 89 VVLASDSDVFNLGGDLALF--CQLIREGDRARLLDYAQRCVRGVHAFHVGLGARAHSIAL 146 Query: 141 INGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDM 200 + G+ LGGG E A+SC IA + ++G PEVL PG G + + + A + Sbjct: 147 VQGNALGGGFEAALSCHTIIA--EEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQKI 204 Query: 201 MLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEE 234 ML G A++ MGLVD++V P G G+ E+ Sbjct: 205 MLEGNLYSAEQLLGMGLVDRVV-PRGQGVAAVEQ 237 >3BPT-A nrPDB Length = 363 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 48/186 (25%), Positives = 87/186 (46%), Gaps = 14/186 (7%) Query: 44 GVKGDVAVVRINSP---NSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG-CFI 99 G KG V+ +N P N+ + ++++ + + W D ++I G F Sbjct: 11 GKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKK-----WEQDPETFLIIIKGAGGKAFC 65 Query: 100 AGADINMLA-ACKTLQEVTQ-LSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQ 157 AG DI +++ A K Q++ +E + + KP VA I+G +GGG+ +++ Q Sbjct: 66 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 125 Query: 158 YRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGL 217 +R+AT+ K + PE +G P GG LP++ G + LTG ++ + G+ Sbjct: 126 FRVATE--KCLFAMPETAIGLFPDVGGGYFLPRLQGKLGYF-LALTGFRLKGRDVYRAGI 182 Query: 218 VDQLVE 223 V+ Sbjct: 183 ATHFVD 188 >3OME-A nrPDB Length = 282 Score = 60.1 bits (144), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 50/191 (26%), Positives = 91/191 (47%), Gaps = 18/191 (9%) Query: 40 HINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFI 99 +I+YGV +A + +N P + N + EL E A D +++ + F Sbjct: 24 YIDYGVADSIATITLNRPEA-ANAQNPELLDELDAAWTRA-AEDNEVKVIILRANGKHFS 81 Query: 100 AGADIN---MLAACKTLQEVTQLSQEAQRIVE---KLEKSTKPIVAAINGSCLGGGLEVA 153 AG D+ + +L+ + Q EA+R ++ + KP +AA+ G C+ GGL + Sbjct: 82 AGHDLRGGGEVPEKISLEFIIQ--HEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLC 139 Query: 154 ISCQYRIATKDRKTVLGTPEVLL--GALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADR 211 C +A+ D + P L+ G + G T L G A +++ TGR++ A+ Sbjct: 140 WPCDLILASDD--ALFSDPVALMGIGGVEYHGHTWEL----GPRKAKEILFTGRALTAEE 193 Query: 212 AKKMGLVDQLV 222 A++ G+V+++V Sbjct: 194 AERTGMVNRVV 204 >1EF9-A nrPDB Length = 261 Score = 55.5 bits (132), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 55/220 (25%), Positives = 98/220 (44%), Gaps = 20/220 (9%) Query: 36 LTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLIS-SK 94 ++ ++N VAV+ N K+N LSK + + ++++ +IR +L + S Sbjct: 1 MSYQYVNVVTINKVAVIEFNY-GRKLNALSKVFIDDLMQALSDL-NRPEIRCIILRAPSG 58 Query: 95 PGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAI 154 F AG DI+ L + ++ ++I ++K KPI++ + GS GG E+ + Sbjct: 59 SKVFSAGHDIHELPSGG--RDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIM 116 Query: 155 SCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKK 214 S IA T TP V LG G L + G +++ T I A RA Sbjct: 117 SSDLIIAAST-STFSMTP-VNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALA 174 Query: 215 MGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADK 254 +G+++ +VE +E LE+ + A +++K Sbjct: 175 VGILNHVVE-------------VEELEDFTLQMAHHISEK 201 >3HE2-A nrPDB Length = 264 Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 43/176 (24%), Positives = 80/176 (45%), Gaps = 17/176 (9%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLA 108 V + + P + N L+ +L E ++ + + A D A++++ + F AGAD++ A Sbjct: 31 VLTIELQRPERR-NALNSQLVEELTQAIRK--AGDGSARAIVLTGQGTAFCAGADLSGDA 87 Query: 109 ACKTLQEVTQLSQEAQRIVE---KLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 + R++E ++ S P+V AING +G GL++A+ C R+ D Sbjct: 88 FAADYPD---------RLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRVVAPD- 137 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL 221 P G +RL +VG A M+L+ + A+ A G+ +++ Sbjct: 138 -AFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRI 192 >2A81-A nrPDB Length = 250 Score = 52.0 bits (123), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 41/176 (23%), Positives = 78/176 (44%), Gaps = 4/176 (2%) Query: 48 DVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINML 107 +V V+ ++ PN K N S+ L + + + A D +R+ V+ F AG D N + Sbjct: 9 EVRVITLDHPN-KHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFNEV 67 Query: 108 AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKT 167 +++ + + + + KP +AA++G +G G + A+ R+ Sbjct: 68 KQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMASTANF 127 Query: 168 VLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVE 223 V+ PE+ G + + G L G +++ +S+ A R LV+Q+VE Sbjct: 128 VM--PELKHG-IGCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVE 180 >2IEX-A nrPDB Length = 272 Score = 51.6 bits (122), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 54/214 (25%), Positives = 97/214 (45%), Gaps = 30/214 (14%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFS-EVMNEIW-----ASDQIRSAVLISSK 94 I Y +A + IN P E+H+ F + +NE+ A D V+I + Sbjct: 14 IIYETYNGIAKITINRP---------EVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTG 64 Query: 95 PG--CFIAGADINMLAACKTL--QEVTQLS-QEAQRIVEKLEKSTKPIVAAINGSCLGGG 149 G F +G D + + E+ +L+ + QR++ + KP++A + G +GGG Sbjct: 65 AGGKAFCSGGDQKVRGHGGYVGEDEIPRLNVLDLQRLIRVI---PKPVIAMVAGYAIGGG 121 Query: 150 LEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRA 209 + + C IA + + G +G+ G G L ++VG A ++ R A Sbjct: 122 HVLHVVCDLTIAADN--AIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTA 179 Query: 210 DRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEV 243 A +MGLV+++V L+ EE T+++ +E+ Sbjct: 180 QEALEMGLVNKVVP-----LEQLEEETVKWAQEI 208 >4JFC-A nrPDB Length = 281 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 46/179 (25%), Positives = 90/179 (50%), Gaps = 6/179 (3%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 +G ++ +++P + N L E+++ E +N + +IRS V+I+ + F AG ++ Sbjct: 32 EGQTLILTLSNPEFR-NALGPEIYAAGIEALNAAENNPEIRS-VVITGEGAVFCAGGNLQ 89 Query: 106 MLAACK-TLQEVTQLSQEA-QRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 L A + EV S E ++ + KP++AA+ G+ G G +A++C + +A Sbjct: 90 RLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAAS 149 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 + V+ V G P GG+ L + + A ++++ G I A R +GLV+++ Sbjct: 150 NAVFVMSYSTV--GLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLVNKVA 206 >6OJM-A nrPDB Length = 286 Score = 49.3 bits (116), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 28/101 (27%), Positives = 53/101 (52%), Gaps = 4/101 (3%) Query: 122 EAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPG 181 E QR++ + K ++A + G +GGG + + C +A+K+ + + + + G Sbjct: 110 EVQRLIRFM---PKVVIAVVPGWAVGGGHSLHVVCDLTLASKEH-AIFKQTDADVTSFDG 165 Query: 182 AGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 G+ L KMVG A ++ GR+ A A +MG+V+++V Sbjct: 166 GYGSAYLAKMVGQKKAREIFFLGRNYSAQEAFEMGMVNKVV 206 >3ADO-A nrPDB Length = 319 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 67/278 (24%), Positives = 126/278 (45%), Gaps = 20/278 (7%) Query: 366 ILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVK----KKALTSFE 421 I+G+GL+G A + G + L D + + + K + + K +L++ E Sbjct: 11 IVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSLSAEE 70 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPI 481 + S+ S+ T + E + E V E+L LK ++ ++++++ D + +S++S L Sbjct: 71 QLSLISSCTNL--AEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLP 128 Query: 482 SEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVII-VVK 540 S++ ++ I H +P + L+E++ +TS T A+ K G+ + V+K Sbjct: 129 SKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVLK 188 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEG-VDPKKL-----DSLTTSFGF--PVGAATLVDEVG 592 + GF R ++SE R+++EG V P L D L + F P+ L E Sbjct: 189 EIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETMHLNAEGM 248 Query: 593 VDVAKHVAEDLGKV---FGE--RFGGGNPELLTQMVSK 625 + +E + +V FG F G E + Q + K Sbjct: 249 LSYCDRYSEGMKRVLKSFGSIPEFSGATVEKVNQAMCK 286 >2UZF-A nrPDB Length = 273 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/207 (22%), Positives = 88/207 (42%), Gaps = 14/207 (6%) Query: 40 HINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFI 99 I Y +A V IN P + N + + +E + + + VL F Sbjct: 14 EIKYEFYEGIAKVTINRPEVR-NAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFC 72 Query: 100 AGADINMLAACKTLQE--VTQLS-QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 +G D + E + +L+ + QR++ + KP++A + G +GGG + + C Sbjct: 73 SGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRII---PKPVIAMVKGYAVGGGNVLNVVC 129 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 IA + + G +G+ G+ L ++VG A ++ R A A MG Sbjct: 130 DLTIAADN--AIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMG 187 Query: 217 LVDQLVEPLGPGLKPPEERTIEYLEEV 243 LV+ +V L+ E+ T+++ +E+ Sbjct: 188 LVNTVVP-----LEKVEDETVQWCKEI 209 >3T88-A nrPDB Length = 289 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 44/199 (22%), Positives = 82/199 (41%), Gaps = 15/199 (7%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLA 108 +A + IN P + N E + + + D I +L + F +G D + Sbjct: 38 IAKITINRPQVR-NAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRG 96 Query: 109 ACKTLQEVTQLSQ----EAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKD 164 ++ + + + QR ++ KP+VA + G +GGG + + C IA + Sbjct: 97 DYGGYKDDSGVHHLNVLDFQR---QIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADN 153 Query: 165 RKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 + G +G+ G G + ++VG A ++ R A +A MGLV+ +V Sbjct: 154 --AIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVP- 210 Query: 225 LGPGLKPPEERTIEYLEEV 243 L E+ T+ + E+ Sbjct: 211 ----LADLEKETVRWCREM 225 >4EML-A nrPDB Length = 275 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/222 (23%), Positives = 95/222 (42%), Gaps = 27/222 (12%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG---- 96 I Y G +A + IN P+ K N + E + ++I +L + P Sbjct: 12 ILYYKAGGIAKIVINRPH-KRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGK 70 Query: 97 -CFIAGADINMLAACKTL--QEVTQLS-QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEV 152 F +G D ++ + Q +L+ + QR++ + K ++A + G +GGG + Sbjct: 71 YAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKV---VIALVAGYAIGGGHVL 127 Query: 153 AISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRA 212 + C IA + + G +G+ G G+ L ++VG A ++ R A A Sbjct: 128 HLVCDLTIAADN--AIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEA 185 Query: 213 KKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADK 254 ++MG+V+ +V P +R LEE I +AK + K Sbjct: 186 ERMGMVNTVV---------PVDR----LEEEGIQWAKEILSK 214 >4Q1J-A nrPDB Length = 268 Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 62/270 (22%), Positives = 108/270 (40%), Gaps = 48/270 (17%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKP---GCFIAGADIN 105 V ++ I S +V + + FS+ + + D I++ I P + G D N Sbjct: 25 VELIEIESAIIQVKMQDRTHKNAFSQELTD----DLIQAFEYIRQNPKYKAVILTGYD-N 79 Query: 106 MLAACKTLQEVTQLSQEAQRIVEKLEKSTK-----PIVAAINGSCLGGGLEVAISCQYRI 160 A+ T + + ++ Q + + S P++AA+ G +GGG + + I Sbjct: 80 YFASGGTQEGLLRIQQGLTKFTDDNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFAD--I 137 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 R++V + G PG G T +PK +G A +++L S R +K G+ Sbjct: 138 VILSRESVYTANFMKYGFTPGMGATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGV--- 194 Query: 221 LVEPLGPGLKPPEERTIEYLEEVAITFAK-------GLADKKISPKRDKGLVEKLTAYAM 273 P P ++Y E+A A+ L D ++P RD+ Sbjct: 195 ------PFKVLPRAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQ----------- 237 Query: 274 TIPFVRQQVYKKVE-----EKVRKQTKGLY 298 +P V +Q E E+V+ + KGLY Sbjct: 238 -LPRVIEQELMMAEKTFHHEEVKSRIKGLY 266 >4J2U-A nrPDB Length = 365 Score = 45.4 bits (106), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 14/171 (8%) Query: 59 SKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQ 118 + +N L+ + E + ++ V+ + P F AG DI L + + Sbjct: 43 AALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIAELHG-RGVAGDHA 101 Query: 119 LSQEAQRIV----EKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEV 174 Q+ R+ +++ KPIV+ + G +GGG V + C R + + PE Sbjct: 102 FGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGG--VGLGCHARHRIVGETSQISMPEC 159 Query: 175 LLGALPGAGGTQ---RLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 +G +P GGT R P +GV + LTG + A G D+ V Sbjct: 160 AIGLVPDVGGTHLLARAPGRIGV----WLGLTGARMGPGDAIFAGFADRFV 206 >3T8B-A nrPDB Length = 334 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 47/206 (22%), Positives = 82/206 (39%), Gaps = 26/206 (12%) Query: 39 THINYGVKGDVAVVRI--NSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG 96 T I Y D A VR+ N P + N E V++ S + +L + P Sbjct: 55 TDITYHRHVDDATVRVAFNRPEVR-NAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPS 113 Query: 97 ------CFIAGADINM-------LAACKTLQEVTQLSQ------EAQRIVEKLEKSTKPI 137 F +G D + A+ T V E QR++ + K + Sbjct: 114 PKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKV---V 170 Query: 138 VAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAA 197 + +NG GGG + + C +A+++ T + +G+ G G+ L + VG A Sbjct: 171 ICLVNGWAAGGGHSLHVVCDLTLASREYARFKQT-DADVGSFDGGYGSAYLARQVGQKFA 229 Query: 198 LDMMLTGRSIRADRAKKMGLVDQLVE 223 ++ GR+ A++ +MG V+ + E Sbjct: 230 REIFFLGRTYTAEQMHQMGAVNAVAE 255 >2NP9-A nrPDB Length = 440 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/90 (33%), Positives = 46/90 (51%), Gaps = 3/90 (3%) Query: 135 KPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGV 194 KP VAA++G +GGG ++ + +A+ D P G +PGA RL + G Sbjct: 285 KPWVAAVDGFAIGGGAQLLLVFDRVLASSD--AYFSLPAAKEGIIPGAANL-RLGRFAGP 341 Query: 195 PAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 + ++L GR I A + LVD++VEP Sbjct: 342 RVSRQVILEGRRIWAKEPEARLLVDEVVEP 371 >4HDT-A nrPDB Length = 353 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 49/183 (26%), Positives = 84/183 (45%), Gaps = 12/183 (6%) Query: 45 VKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADI 104 V+G V ++ +N P + +N+L+ + + +E + D +R+ +L + AG D+ Sbjct: 15 VEGGVGLLTLNRPKA-INSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLCAGGDV 73 Query: 105 NML--AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIAT 162 + +A E + + R+ + + KP V+ ++G +GGG+ V R+ T Sbjct: 74 VAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGNVRVVT 133 Query: 163 KDRKTVLGTPEVLLGALPGAGGT---QRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVD 219 K + PEV +G +P GGT R P +G+ AA LTG A MG D Sbjct: 134 DTTK--MAMPEVGIGFIPDVGGTYLLSRAPGKLGLHAA----LTGAPFSGADAIVMGFAD 187 Query: 220 QLV 222 V Sbjct: 188 HYV 190 >3JU1-A nrPDB Length = 407 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 60/231 (25%), Positives = 102/231 (44%), Gaps = 18/231 (7%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQ-IRSAVLISSKPGCFIAGADINML 107 V VV +N + +N L ++ + +N +W D I VL S F AG D+ L Sbjct: 52 VGVVTLNVEKA-LNALDLDMVRAMTVQLN-LWKKDPLIACVVLDGSGEKAFCAGGDVRAL 109 Query: 108 --AACKTLQEVTQLS----QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIA 161 A+ +VT+++ +E R+ L KP++ +G +GGGL + +++ Sbjct: 110 YHASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLGLMAGASHKVV 169 Query: 162 TKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL 221 T+ + + PEV +G P GG+ L +M G L + LT + A A +GL D Sbjct: 170 TETSR--IAMPEVTIGLYPDVGGSYFLNRMPG-KMGLFLGLTAYHMNAADACYVGLADHY 226 Query: 222 VEPLGPGLKPPEERTIEYLEEVAI------TFAKGLADKKISPKRDKGLVE 266 + L T+++ + A+ T L+++ PK D L E Sbjct: 227 LNRDDKELMFDAMATLDWSDSPALNHQRLDTMINELSNQVDIPKGDSVLAE 277 >3CTV-A nrPDB Length = 110 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 39/72 (54%), Gaps = 5/72 (6%) Query: 682 VNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYG 741 +NEAV ++ G+ ATP + D GL P GPF +GA++I RL++ +G Sbjct: 28 INEAVKLVEMGV-ATPQDIDTAIKLGLNRP---FGPFELAKQFGAEQIAKRLEELAKQFG 83 Query: 742 KQ-FTPCQLLAD 752 K+ F P + L + Sbjct: 84 KKIFEPAKTLKE 95 >3I47-A nrPDB Length = 268 Score = 33.5 bits (75), Expect = 0.40, Method: Compositional matrix adjust. Identities = 56/227 (24%), Positives = 99/227 (43%), Gaps = 21/227 (9%) Query: 47 GDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINM 106 G + + RI+ N+ N L E+ +N+ +R +++ + F AGAD+ Sbjct: 15 GLLTMNRISKHNAFDNQLLTEMRIRLDSAINDT----NVR-VIVLKANGKHFSAGADLTW 69 Query: 107 LAACKTLQEVTQLSQEAQ--RIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKD 164 + + E L ++ + +S KP +A + G+ GGG +A +C IA+ Sbjct: 70 MQSMANFTEEENLEDSLVLGNLMYSISQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTS 129 Query: 165 RKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 + EV LG +P A + + + +G AA + ++ A RA + LV V P Sbjct: 130 ARFCFS--EVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCV-P 185 Query: 225 LGPGLKPPEERTIEYLEEV------AITFAKGLADKKISPKRDKGLV 265 L E T++Y ++ A+ +K LA + K D+ LV Sbjct: 186 DDTLL----EFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELV 228 >4KWB-A nrPDB Length = 273 Score = 33.1 bits (74), Expect = 0.49, Method: Compositional matrix adjust. Identities = 52/208 (25%), Positives = 86/208 (41%), Gaps = 24/208 (11%) Query: 18 ILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMN 77 +L + GY R F + L R + VKG V+++NSP V S E+H + E+ Sbjct: 28 LLGADGYNHRTFLKN---LERAKDDKTVKG--IVLKVNSPGGGVYE-SAEIHKKLEEIKK 81 Query: 78 EIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQE---VTQLSQEAQRIVEKLEKST 134 E + + +S G +I+ A + A +TL V S ++ +KL Sbjct: 82 ETKKPIYVSMGSMAAS-GGYYISTAADKIFATPETLTGSLGVIMESVNYSKLADKL---- 136 Query: 135 KPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGV 194 I+ + G I R TK+ K ++ + + G + K G+ Sbjct: 137 -----GISFETIKSGAHADIMSPSREMTKEEKNIMQS----MVDNSYEGFVDVISKGRGM 187 Query: 195 P-AALDMMLTGRSIRADRAKKMGLVDQL 221 P A + + GR +AKK+ LVD+L Sbjct: 188 PKAEVKKIADGRVYDGRQAKKLNLVDEL 215 >3RST-A nrPDB Length = 240 Score = 33.1 bits (74), Expect = 0.52, Method: Compositional matrix adjust. Identities = 52/208 (25%), Positives = 86/208 (41%), Gaps = 24/208 (11%) Query: 18 ILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMN 77 +L + GY R F + L R + VKG V+++NSP V S E+H + E+ Sbjct: 23 LLGADGYNHRTFLKN---LERAKDDKTVKG--IVLKVNSPGGGVYE-SAEIHKKLEEIKK 76 Query: 78 EIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQE---VTQLSQEAQRIVEKLEKST 134 E + + +S G +I+ A + A +TL V S ++ +KL Sbjct: 77 ETKKPIYVSMGSMAAS-GGYYISTAADKIFATPETLTGSLGVIMESVNYSKLADKL---- 131 Query: 135 KPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGV 194 I+ + G I R TK+ K ++ + + G + K G+ Sbjct: 132 -----GISFETIKSGAHADIMSPSREMTKEEKNIMQS----MVDNSYEGFVDVISKGRGM 182 Query: 195 P-AALDMMLTGRSIRADRAKKMGLVDQL 221 P A + + GR +AKK+ LVD+L Sbjct: 183 PKAEVKKIADGRVYDGRQAKKLNLVDEL 210 >6C25-A nrPDB Length = 439 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 41/96 (42%), Gaps = 6/96 (6%) Query: 378 QVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTS---FERDSIFSNLTGQLD 434 +++DK +T + + + RG ++ DKV ++AL F RD + LT LD Sbjct: 119 HIALDKARETHMGKSAIGTTGRGIGPAYE---DKVARRALRVGDLFHRDRFANKLTELLD 175 Query: 435 YQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHC 470 Y F + + SL L+ E + P C Sbjct: 176 YHNFVLTQYFKQPAVDLESLLGESLQWAEELRPMVC 211 >2BC1-A nrPDB Length = 490 Score = 30.4 bits (67), Expect = 2.7, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 24/40 (60%) Query: 358 QKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTAL 397 KD+K +A++GAG +G +A+ KG + +L D T L Sbjct: 191 NKDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCL 230 >3GVH-A nrPDB Length = 324 Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 42/82 (51%), Gaps = 11/82 (13%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERD 423 +A++G+G++G +A ++ GLK L D L + G Q KGL D + + F+ Sbjct: 10 IALIGSGMIGGTLAHLA---GLKE-LGDVVLFDIAEGTPQ-GKGL-DIAESSPVDGFD-- 61 Query: 424 SIFSNLTGQLDYQGFEKADMVI 445 + TG DY E AD+VI Sbjct: 62 ---AKFTGANDYAAIEGADVVI 80 >8ABP-A nrPDB Length = 306 Score = 29.6 bits (65), Expect = 4.6, Method: Compositional matrix adjust. Identities = 57/247 (23%), Positives = 96/247 (38%), Gaps = 37/247 (14%) Query: 231 PPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKV 290 P E+T+ ++ +A + AKG PK +V K Y M + V Q V Sbjct: 41 PDGEKTLNAIDSLAASGAKGFVICTPDPKLGSAIVAKARGYDMKVIAVDDQF-------V 93 Query: 291 RKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCK 350 + K + PL ++ K G QG + E QK G V KES A+M + ++ Sbjct: 94 NAKGKPMDTVPLVMLAATKIGERQGQE--LYKEMQKRGWDV--KES-AVMAITANELDTA 148 Query: 351 KNKF----------GAPQKDVKHLAILGAGLMGAGIAQVS-------VDKGLKTILKDAT 393 + + G P+K + + + GA A S V L + D+T Sbjct: 149 RRRTTGSMDALKAAGFPEKQIYQVPTKSNDIPGAFDAANSMLVQHPEVKHWLIVGMNDST 208 Query: 394 LTALDRGQQ-QVFK-------GLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVI 445 + R + Q FK G+N L+ + + +L D G++ ++M+ Sbjct: 209 VLGGVRATEGQGFKAADIIGIGINGVDAVSELSKAQATGFYGSLLPSPDVHGYKSSEMLY 268 Query: 446 EAVFEDL 452 V +D+ Sbjct: 269 NWVAKDV 275 >5XEF-A nrPDB Length = 123 Score = 29.6 bits (65), Expect = 5.4, Method: Composition-based stats. Identities = 27/111 (24%), Positives = 50/111 (45%), Gaps = 3/111 (2%) Query: 75 VMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKST 134 + N+I S+ I++ + I + C I + L LQ+ +L ++ +RI E+L+ Sbjct: 10 MQNDIMTSNPIKNTIFIYER--CIIEFRKLEELLNTFKLQDGDELLEKLERIFEELKLQL 67 Query: 135 KP-IVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGG 184 P I + S G ++I Q T++ K + +VL + G G Sbjct: 68 NPDITKDLYDSLFGLYDWISIQIQTMKVTREVKDIDAIVQVLQDLIDGYRG 118 >4C7U-A nrPDB Length = 225 Score = 28.9 bits (63), Expect = 7.7, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 24/40 (60%) Query: 354 FGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDAT 393 FG+ + VK ++ GA + G+G + +DK LK ++ D T Sbjct: 127 FGSLEGLVKKMSAEGAAVQGSGWVWLGLDKELKKLVVDTT 166 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5ZRV-A nrPDB 958 0.0 2WTB-A nrPDB 672 0.0 6IUM-B nrPDB 671 0.0 3ZWA-A nrPDB 666 0.0 2D3T-A nrPDB 647 0.0 4B3J-A nrPDB 616 e-176 1ZCJ-A nrPDB 479 e-135 3K6J-A nrPDB 415 e-116 6ACQ-A nrPDB 359 2e-99 4KUG-A nrPDB 357 1e-98 1F14-A nrPDB 350 1e-96 3HDH-A nrPDB 347 9e-96 4J0E-A nrPDB 343 1e-94 3MOG-A nrPDB 337 1e-92 4PZE-A nrPDB 336 2e-92 6HRD-A nrPDB 310 1e-84 4OM8-A nrPDB 266 2e-71 4DYD-A nrPDB 266 3e-71 1ZEJ-A nrPDB 261 6e-70 3F3S-A nrPDB 251 8e-67 3ADO-A nrPDB 232 5e-61 5ZAI-A nrPDB 209 4e-54 2IEX-A nrPDB 209 5e-54 5Z7R-A nrPDB 204 1e-52 3T88-A nrPDB 203 3e-52 4JCS-A nrPDB 197 2e-50 2UZF-A nrPDB 196 2e-50 5WYB-B nrPDB 196 3e-50 3H81-A nrPDB 193 3e-49 4EML-A nrPDB 192 5e-49 2HW5-A nrPDB 189 3e-48 2DUB-A nrPDB 189 4e-48 2PPY-A nrPDB 189 4e-48 3MOY-A nrPDB 185 6e-47 4FZW-A nrPDB 181 1e-45 5JBW-A nrPDB 178 7e-45 5YLO-A nrPDB 174 9e-44 4JWV-A nrPDB 174 2e-43 6OJM-A nrPDB 172 6e-43 1EF9-A nrPDB 169 3e-42 1NZY-B nrPDB 169 3e-42 3OME-A nrPDB 167 2e-41 3HIN-A nrPDB 167 2e-41 3BPT-A nrPDB 166 5e-41 2VSU-C nrPDB 166 5e-41 2A81-A nrPDB 164 1e-40 5VE2-A nrPDB 164 2e-40 5MRE-88 nrPDB 163 3e-40 1XX4-A nrPDB 161 1e-39 3T8B-A nrPDB 159 5e-39 4J2U-A nrPDB 159 6e-39 4IZC-A nrPDB 157 2e-38 3JU1-A nrPDB 156 5e-38 4FZW-C nrPDB 150 2e-36 3HE2-A nrPDB 148 9e-36 4JSB-A nrPDB 146 3e-35 3LAO-A nrPDB 145 8e-35 4HDT-A nrPDB 144 1e-34 4JFC-A nrPDB 141 2e-33 5KJP-A nrPDB 139 3e-33 4Q1J-A nrPDB 129 4e-30 3M6N-A nrPDB 123 3e-28 2NP9-A nrPDB 118 1e-26 3CTV-A nrPDB 71 1e-12 Sequences not found previously or not previously below threshold: 4ZU2-A nrPDB 137 1e-32 3I47-A nrPDB 129 5e-30 3HP0-A nrPDB 107 2e-23 4HC8-A nrPDB 101 1e-21 4ZDC-A nrPDB 79 6e-15 2BC1-A nrPDB 48 1e-05 6AON-A nrPDB 44 3e-04 4R16-A nrPDB 43 5e-04 2EQ6-A nrPDB 42 9e-04 3X2F-A nrPDB 42 0.001 1F8S-A nrPDB 41 0.002 2GF2-A nrPDB 40 0.003 3KVE-A nrPDB 40 0.003 4D3F-A nrPDB 40 0.004 3OJO-A nrPDB 40 0.004 4WJI-A nrPDB 40 0.005 4XRR-A nrPDB 40 0.005 5DT9-A nrPDB 39 0.006 4ND4-A nrPDB 39 0.006 1REO-A nrPDB 39 0.006 3GGO-A nrPDB 39 0.007 2G5C-A nrPDB 39 0.007 5X6R-A nrPDB 39 0.007 5U8W-A nrPDB 39 0.008 5ER0-A nrPDB 39 0.009 4OQZ-A nrPDB 38 0.014 1PS9-A nrPDB 38 0.015 6IHE-A nrPDB 37 0.022 4E84-A nrPDB 37 0.029 1MV8-A nrPDB 37 0.032 4OQY-A nrPDB 37 0.034 5Y77-A nrPDB 36 0.053 6BZ0-A nrPDB 36 0.056 2HMT-A nrPDB 36 0.069 4PRK-A nrPDB 36 0.070 4J90-A nrPDB 36 0.072 5BUT-A nrPDB 36 0.074 3LAD-A nrPDB 36 0.077 4ZGS-A nrPDB 35 0.080 5N2I-A nrPDB 35 0.094 6C6P-A nrPDB 35 0.11 4E21-A nrPDB 35 0.12 5TR3-A nrPDB 35 0.12 1VPD-A nrPDB 35 0.12 3G0O-A nrPDB 35 0.13 1Q1R-A nrPDB 35 0.14 3TL2-A nrPDB 35 0.14 1A5Z-A nrPDB 35 0.14 1LTH-T nrPDB 35 0.14 5JE8-A nrPDB 35 0.14 3ZHB-A nrPDB 35 0.14 3G5Q-A nrPDB 35 0.14 6ABJ-A nrPDB 35 0.15 2YQ5-A nrPDB 35 0.17 1SEZ-A nrPDB 35 0.17 3KB6-A nrPDB 34 0.18 6QGL-A nrPDB 34 0.19 2UYY-A nrPDB 34 0.19 2V8U-A nrPDB 34 0.22 3WFI-A nrPDB 34 0.22 2R9Z-A nrPDB 34 0.22 5O3Z-A nrPDB 34 0.23 3FG2-P nrPDB 34 0.24 1X14-A nrPDB 34 0.24 4K28-A nrPDB 34 0.36 5JFC-L nrPDB 34 0.37 5VJ7-A nrPDB 33 0.40 4ROS-A nrPDB 33 0.41 3ZZN-A nrPDB 33 0.42 3H2Z-A nrPDB 33 0.42 4A6N-B nrPDB 33 0.47 4FFM-A nrPDB 33 0.50 3VPX-A nrPDB 33 0.52 2EW2-A nrPDB 33 0.55 4HTF-A nrPDB 33 0.55 3WSV-A nrPDB 33 0.55 3VTF-A nrPDB 33 0.56 2HQM-A nrPDB 33 0.58 5MH6-A nrPDB 33 0.59 5UYY-A nrPDB 33 0.61 4A7P-A nrPDB 33 0.64 3N58-A nrPDB 33 0.65 4Q28-A nrPDB 32 0.69 4ZCC-A nrPDB 32 0.70 3NEP-X nrPDB 32 0.78 5X68-A nrPDB 32 0.79 1YB4-A nrPDB 32 0.79 4MOP-A nrPDB 32 0.81 3Q3C-A nrPDB 32 0.87 4UEJ-A nrPDB 32 0.87 3KKJ-A nrPDB 32 0.87 2LDB-A nrPDB 32 0.89 1AHH-A nrPDB 32 0.94 1Y6J-A nrPDB 32 0.96 5ZIK-A nrPDB 32 0.98 2W8Z-A nrPDB 32 1.00 6CI9-A nrPDB 32 1.1 3HWR-A nrPDB 32 1.1 2VHY-A nrPDB 32 1.1 5X1Y-B nrPDB 32 1.2 3ATQ-A nrPDB 32 1.2 2PA3-A nrPDB 32 1.2 3AXS-A nrPDB 32 1.2 2F1K-A nrPDB 32 1.3 3DC2-A nrPDB 32 1.3 1HL3-A nrPDB 32 1.3 3PEF-A nrPDB 32 1.4 1C0L-A nrPDB 32 1.4 1GUZ-A nrPDB 32 1.4 5JXW-A nrPDB 32 1.4 2EEZ-A nrPDB 32 1.4 1XDW-A nrPDB 31 1.5 3KYB-A nrPDB 31 1.5 3BF0-A nrPDB 31 1.6 3LXD-A nrPDB 31 1.7 5U2O-A nrPDB 31 1.8 3BHF-A nrPDB 31 1.8 3CGD-A nrPDB 31 2.0 1GV0-A nrPDB 31 2.1 2V3B-A nrPDB 31 2.2 3NJ4-A nrPDB 31 2.4 5OCM-A nrPDB 31 2.4 1CF2-P nrPDB 30 2.5 1BG6-A nrPDB 30 2.7 4THI-A nrPDB 30 2.7 2QPO-A nrPDB 30 2.7 4DGK-A nrPDB 30 2.8 2CZG-A nrPDB 30 2.8 3DOJ-A nrPDB 30 2.8 5IKL-B nrPDB 30 2.9 3K30-A nrPDB 30 3.0 3UPY-A nrPDB 30 3.2 3PDU-A nrPDB 30 3.2 2ZLF-A nrPDB 30 3.4 4NAS-A nrPDB 30 3.5 1PZF-A nrPDB 30 3.5 4OH1-A nrPDB 30 3.8 3N6R-B nrPDB 30 4.1 1GPJ-A nrPDB 30 4.1 5U1O-A nrPDB 30 4.2 3ICS-A nrPDB 30 4.3 3WTC-A nrPDB 30 4.5 1LJU-A nrPDB 30 4.8 4WEQ-A nrPDB 30 5.0 3AEO-A nrPDB 30 5.0 4C2K-A nrPDB 30 5.2 5Z9Y-A nrPDB 30 5.6 6CAU-A nrPDB 30 5.6 5J5Z-A nrPDB 29 6.1 3CKY-A nrPDB 29 6.3 5A9T-A nrPDB 29 6.4 3NRA-A nrPDB 29 6.5 3DO5-A nrPDB 29 6.6 5T5Q-A nrPDB 29 8.1 1LU9-A nrPDB 29 8.9 5IZ4-A nrPDB 29 9.2 1SKF-A nrPDB 29 9.8 >5ZRV-A nrPDB Length = 763 Score = 958 bits (2475), Expect = 0.0, Method: Composition-based stats. Identities = 763/763 (100%), Positives = 763/763 (100%) Query: 1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK 60 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK Sbjct: 1 MVACRAIGILSRFSAFRILRSRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSK 60 Query: 61 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLS 120 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLS Sbjct: 61 VNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLS 120 Query: 121 QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALP 180 QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALP Sbjct: 121 QEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALP 180 Query: 181 GAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYL 240 GAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYL Sbjct: 181 GAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYL 240 Query: 241 EEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA 300 EEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA Sbjct: 241 EEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPA 300 Query: 301 PLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD 360 PLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD Sbjct: 301 PLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD 360 Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF Sbjct: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP Sbjct: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK Sbjct: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA 600 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA Sbjct: 541 DGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA 600 Query: 601 EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK 660 EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK Sbjct: 601 EDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLK 660 Query: 661 LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF 720 LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF Sbjct: 661 LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF 720 Query: 721 VDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ 763 VDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ Sbjct: 721 VDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSPNKKFYQ 763 >2WTB-A nrPDB Length = 725 Score = 672 bits (1735), Expect = 0.0, Method: Composition-based stats. Identities = 230/739 (31%), Positives = 359/739 (48%), Gaps = 44/739 (5%) Query: 33 SALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLIS 92 S +T + G G VAV+ + +P VN+LS ++ E + + ++ A++I+ Sbjct: 3 SRTKGKTVMEVGGDG-VAVITLINP--PVNSLSFDVLYNLKSNYEEALSRNDVK-AIVIT 58 Query: 93 SKPGCFIAGADINMLAAC--KTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGL 150 G F G DI+ ++E I + LE + KP VAAI+G LGGGL Sbjct: 59 GAKGRFSGGFDISGFGEMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGL 118 Query: 151 EVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRAD 210 E+A++C RI+ + LG PE+ LG +PG GGTQRLP++VG+ AL+M+LT + ++A+ Sbjct: 119 ELAMACHARISAPAAQ--LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAE 176 Query: 211 RAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK---ISPKRDKGLVEK 267 +GL+D +V P L A +A + ++ +S + Sbjct: 177 EGHSLGLIDAVVPP-------------AELVTTARRWALDIVGRRKPWVSSVSKTDKLPP 223 Query: 268 LTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKF 327 L + F + Q K+ PL +D ++ GI G AG E++ Sbjct: 224 LGEAREILTFAKAQTLKRAPN---------MKHPLMCLDAIEVGIVSGPRAGLEKEAEVA 274 Query: 328 GELVMTKESKALMGLYHGQVLCKKNK----FGAPQKDVKHLAILGAGLMGAGIAQVSVDK 383 ++V +K L+ ++ Q K G + +K +AI+G GLMG+GIA + Sbjct: 275 SQVVKLDTTKGLIHVFFSQRGTAKVPGVTDRGLVPRKIKKVAIIGGGLMGSGIATALILS 334 Query: 384 GLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADM 443 ILK+ L+ G +V L +V+K +++ + + S L G LDY+ F DM Sbjct: 335 NYPVILKEVNEKFLEAGIGRVKANLQSRVRKGSMSQEKFEKTMSLLKGSLDYESFRDVDM 394 Query: 444 VIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPV 503 VIEAV E++SLK ++ ++E P HCI ASNTS + +++I +K ++++G H+FSP Sbjct: 395 VIEAVIENISLKQQIFADLEKYCPQHCILASNTSTIDLNKIGERTKSQDRIVGAHFFSPA 454 Query: 504 DKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQ 563 M LLEI+ T TS + VG K K +VV + GF R P + +++ Sbjct: 455 HIMPLLEIVRTNHTSAQVIVDLLDVGKKIKKTPVVVGNCTGFAVNRMFFPYTQAAMFLVE 514 Query: 564 EGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMV 623 G DP +D + FG P+G L D VG VA A + F ER ++ M Sbjct: 515 CGADPYLIDRAISKFGMPMGPFRLCDLVGFGVAIATATQFIENFSER--TYKSMIIPLMQ 572 Query: 624 SKGFLGRKSGKGFYIYQEGVKRK---DLNSDMDSI--LASLKLPPKSEVSSDEDIQFRLV 678 G + KGFY+Y + K K +L ++ ++ +KL PK S++DI Sbjct: 573 EDKRAGEATRKGFYLYDDKRKAKPDPELKKYIEKARSISGVKLDPKLANLSEKDIIEMTF 632 Query: 679 TRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEA 738 VNEA EGI A+ DI + G+GFPP GG + D G++ I RL ++ Sbjct: 633 FPVVNEACRVFAEGIAVKAADLDIAGIMGMGFPPYRGGIMFWADSIGSKYIYSRLDEWSK 692 Query: 739 AYGKQFTPCQLLADHANSP 757 AYG+ F PC LA+ + Sbjct: 693 AYGEFFKPCAFLAERGSKG 711 >6IUM-B nrPDB Length = 701 Score = 671 bits (1730), Expect = 0.0, Method: Composition-based stats. Identities = 231/728 (31%), Positives = 357/728 (49%), Gaps = 52/728 (7%) Query: 43 YGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGA 102 Y V+ VAV+ +++P VN L E M D A++I+ F GA Sbjct: 5 YQVQDGVAVITLDNP--PVNGLGHSTRLGIVEGMTRAL-DDAAVKAIVITGAGKAFSGGA 61 Query: 103 DINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIAT 162 DI K +QE T ++ LE S+KP+VAA++ +GGGLE+A+ C YR+A+ Sbjct: 62 DIREFNTPKAMQEPT-----LHSVIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRVAS 116 Query: 163 KDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 K + + PEV LG LPGAGGTQRLP+++G+ AA +M+++G + +++ L D++V Sbjct: 117 KGAQ--IALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIV 174 Query: 223 EPLGPGLKPPEERTIEYLEEVAITFAKGL-ADKKISPK--RDKGLVEKLTAYAMTIPFVR 279 + A+ FA+ + A PK K E Y + F R Sbjct: 175 DGDVLPA--------------AVKFAQNVGAATGPHPKVRDLKVRHENPEGY---LGFAR 217 Query: 280 QQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKAL 339 V + +PAPLK ++ V G + + G E + F LV T ES+AL Sbjct: 218 NTVAAMAKN---------FPAPLKCLEAV-AGSLKPFEQGLKQEREGFLYLVTTPESRAL 267 Query: 340 MGLYHGQVLCKK---NKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 + G+ K G P + ++ +A++GAG MG GI+ ++ G+ + + A Sbjct: 268 RHAFFGERAASKIPDVPEGTPTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEA 327 Query: 397 LDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKH 456 LDRG + K + KK LT + + L+ L Y + AD++IEAVFE++ +K Sbjct: 328 LDRGVGIIRKNYENSAKKGKLTQEKVEQRMGLLSTTLSYDDLKDADLIIEAVFEEMGVKE 387 Query: 457 RVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEK 516 V K+++ V I ASNTS L +++IA+ +KRP+ V+GMH+FSP + M+LLE++ EK Sbjct: 388 TVFKKLDEVAKQGAILASNTSTLDVNKIASFTKRPQDVVGMHFFSPANVMKLLEVVRGEK 447 Query: 517 TSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTT 576 T KD A+ + VG K K +V GF R + + +L EG P+++D Sbjct: 448 TGKDVLATVMQVGKKIKKTAVVSGVCDGFIGNRMIEQYSRQAGYLLDEGALPEQVDKAIE 507 Query: 577 SFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGF 636 FGF +G + D G D+ + + E +LL +M G G+K+G G+ Sbjct: 508 KFGFAMGPFRMGDLAGNDIGWAIRKRRAVDKPEIQYSKTADLLCEM---GRFGQKTGAGW 564 Query: 637 YIYQEGVKRKDLNSDMDSILA--SLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGIL 694 Y Y+ G ++ N ++ ++ S L SDE+I RLV VNE L+EGI Sbjct: 565 YDYKAGDRKPYPNQQVNDMIVQHSKDLGITRRKISDEEIVERLVFALVNEGARILEEGIA 624 Query: 695 ATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAY---GKQFTP-CQLL 750 + ++ D+ + G GFP GGP + D G + +K+Y Y Q P Q L Sbjct: 625 SKASDIDMVYLTGYGFPLFRGGPMLYADQVGLYNVALSMKRYAKGYHGEAWQVAPLLQKL 684 Query: 751 ADHANSPN 758 AD N Sbjct: 685 ADEGKGFN 692 >3ZWA-A nrPDB Length = 742 Score = 666 bits (1717), Expect = 0.0, Method: Composition-based stats. Identities = 218/733 (29%), Positives = 356/733 (48%), Gaps = 73/733 (9%) Query: 48 DVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINML 107 +A++R+ +P VN +S + E + + SD A++I G F AGADI+ Sbjct: 30 SLAMIRLCNP--PVNAVSPTVIREVRNGLQKA-GSDHTVKAIVICGANGNFCAGADIHGF 86 Query: 108 AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKT 167 +A +V+++++ KP++AAI G LGGGLE+A+ C YRIA + K Sbjct: 87 SAFTP-------GLALGSLVDEIQRYQKPVLAAIQGVALGGGLELALGCHYRIA--NAKA 137 Query: 168 VLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGP 227 +G PEV LG LPGA GTQ LP++VGVP ALD++ +G+ + AD A ++G++D +V+ Sbjct: 138 RVGLPEVTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDP- 196 Query: 228 GLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQ--QVYKK 285 E AI FA+ + DK I P+R + +P + V+ + Sbjct: 197 -------------VEEAIKFAQKIIDKPIEPRR---------IFNKPVPSLPNMDSVFAE 234 Query: 286 VEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHG 345 KVRKQ G+ AP + ++ ++ + G E + F L + ++KAL + Sbjct: 235 AIAKVRKQYPGVL-APETCVRSIQASVKHPYEVGIKEEEKLFMYLRASGQAKALQYAFFA 293 Query: 346 QVLCKKNKFGAP---------QKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 + NK+ P + V + +LG G MG GIA G+ + ++ Sbjct: 294 EK--SANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGISVVAVESDPKQ 351 Query: 397 LDRGQQQVFKGLN---DKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLS 453 LD ++ + L + + S + FS+ T +L D+V+EAVFED++ Sbjct: 352 LDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELS-----TVDLVVEAVFEDMN 406 Query: 454 LKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIIT 513 LK +V E+ A+ +NTSAL + +IA+ + RP+ VIG H+FSP M+LLE+I Sbjct: 407 LKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHFFSPAHVMRLLEVIP 466 Query: 514 TEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDS 573 + +S T A+ +++ K GK+ +VV + GF R LAP ++ +L+EG P+ +D Sbjct: 467 SRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGFFLLEEGSKPEDVDG 526 Query: 574 LTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNP----------ELLTQMV 623 + FGF +G + D G+DV + + G + G G P L + Sbjct: 527 VLEEFGFKMGPFRVSDLAGLDVGWKIRKGQG-LTGPSLPPGTPVRKRGNSRYSPLGDMLC 585 Query: 624 SKGFLGRKSGKGFYIYQEGVKR-KDLNSDMDSILASLKLPPK--SEVSSDEDIQFRLVTR 680 G G+K+GKG+Y Y + + R + + + L+ + S E+I R + Sbjct: 586 EAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQRTISKEEILERCLYS 645 Query: 681 FVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAY 740 +NEA L+EG+ A P D+ + G G+P GGP + G ++++L+KY Sbjct: 646 LINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEKLQKYYRQN 705 Query: 741 GK--QFTPCQLLA 751 Q P L Sbjct: 706 PDIPQLEPSDYLR 718 Score = 49.0 bits (115), Expect = 9e-06, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 6/87 (6%) Query: 546 YTTRCLAPMMSEVIRILQEG--VDPKKLDSLTT-SFGFPV---GAATLVDEVGVDVAKHV 599 RCL +++E RIL+EG P+ +D + +G+P G VG+ Sbjct: 638 ILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEK 697 Query: 600 AEDLGKVFGERFGGGNPELLTQMVSKG 626 + + + + L ++V++G Sbjct: 698 LQKYYRQNPDIPQLEPSDYLRRLVAQG 724 >2D3T-A nrPDB Length = 715 Score = 647 bits (1668), Expect = 0.0, Method: Composition-based stats. Identities = 235/724 (32%), Positives = 355/724 (49%), Gaps = 29/724 (4%) Query: 45 VKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADI 104 ++ + ++ + VN ++ +E + ++ I A ++ ++ SS FI GADI Sbjct: 13 LESGIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIV-SSGKDVFIVGADI 71 Query: 105 NMLAACKTL--QEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIAT 162 L E+ + EA +I E P VAAING LGGGLE+ ++ +R+ Sbjct: 72 TEFVENFKLPDAELIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMA 131 Query: 163 KDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 K +G PEV LG PG GGT RLP+++GV A++ + +G+ RA+ A K+ VD +V Sbjct: 132 DSAK--IGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVV 189 Query: 223 --EPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQ 280 + LG +R I + K +E++ A+ FV Sbjct: 190 TADKLGAAALDLIKRAIS------GELDYKAKRQPKLEKLKLNAIEQMMAFETAKGFVAG 243 Query: 281 QVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALM 340 Q YPAP++ I ++ G D E+ F +L T S L+ Sbjct: 244 QAGPN------------YPAPVEAIKTIQKAANFGRDKALEVEAAGFAKLAKTSASNCLI 291 Query: 341 GLY-HGQVLCKKNK-FGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD 398 GL+ + Q L KK K + KDVK A+LGAG+MG GIA S KG ++KD ++ Sbjct: 292 GLFLNDQELKKKAKVYDKIAKDVKQAAVLGAGIMGGGIAYQSASKGTPILMKDINEHGIE 351 Query: 399 RGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRV 458 +G + K L +V K +T + + + + L Y F D+V+EAV E+ +K V Sbjct: 352 QGLAEAAKLLVGRVDKGRMTPAKMAEVLNGIRPTLSYGDFGNVDLVVEAVVENPKVKQAV 411 Query: 459 LKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTS 518 L EVE + + I ASNTS + IS +A KRPE +GMH+F+PV M L+E+I EK+S Sbjct: 412 LAEVENHVREDAILASNTSTISISLLAKALKRPENFVGMHFFNPVHMMPLVEVIRGEKSS 471 Query: 519 KDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSF 578 A+ VA K GK IVV D PGF R L P +++ GVD ++D + F Sbjct: 472 DLAVATTVAYAKKMGKNPIVVNDCPGFLVNRVLFPYFGGFAKLVSAGVDFVRIDKVMEKF 531 Query: 579 GFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYI 638 G+P+G A L+D VG+D H + + + F +R + + LG+K+GKGFY Sbjct: 532 GWPMGPAYLMDVVGIDTGHHGRDVMAEGFPDRMKDDRRSAIDALYEAKRLGQKNGKGFYA 591 Query: 639 YQEGVKRKDLNSDMDSILASLK-LPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGILATP 697 Y+ K K S+L LK + + +DEDI ++ E V CL++GI+ T Sbjct: 592 YEADKKGKQKKLVDSSVLEVLKPIVYEQRDVTDEDIINWMMIPLCLETVRCLEDGIVETA 651 Query: 698 AEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLKKYEAAYGKQFTPCQLLADHANSP 757 AE D+G V+G+GFP GG R++D G + V +Y G + P L + A + Sbjct: 652 AEADMGLVYGIGFPLFRGGALRYIDSIGVAEFVALADQYA-ELGALYHPTAKLREMAKNG 710 Query: 758 NKKF 761 F Sbjct: 711 QSFF 714 >4B3J-A nrPDB Length = 736 Score = 616 bits (1588), Expect = e-176, Method: Composition-based stats. Identities = 226/723 (31%), Positives = 357/723 (49%), Gaps = 34/723 (4%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 + + ++ P+ N +++ + ++ + A + V+++S F AG D+ Sbjct: 28 ADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVK 87 Query: 106 ML--AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 + A + +V + +R + LE KP+VAAING+ LGGGLE+A++C +RIA Sbjct: 88 TMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAAD 147 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAA-LDMMLTGRSIRADRAKKMGLVDQLV 222 + + LG PEV LG LPG GG R +M G+ A + ++ G + +AK++GLVD+LV Sbjct: 148 VKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELV 207 Query: 223 EPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQV 282 ++ +++E G + P KG K+ + P + + Sbjct: 208 ----ATVEELVPAAKAWIKEELKANPDGAG---VQPWDKKGY--KMPGGTPSSPGL-AAI 257 Query: 283 YKKVEEKVRKQTKGL-YPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMG 341 +RKQ KG PAP I+ G + D ES+ F LV + +K +M Sbjct: 258 LPSFPSNLRKQLKGAPMPAPRAILAAAVEGAQVDFDTASRIESRYFASLVTGQVAKNMMQ 317 Query: 342 LYHGQVLCKKNKFGAPQ----KDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTAL 397 + + P+ +K + +LGAG+MGAGIA VS G + +LKD +L A Sbjct: 318 AFFFDLQAINAGGSRPEGIGKTPIKRIGVLGAGMMGAGIAYVSAKAGYEVVLKDVSLEAA 377 Query: 398 DRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHR 457 +G+ K +++ T D++ + +T D F+ D VIEAVFE+ LKH+ Sbjct: 378 AKGKGYSEKLEAKALERGRTTQERSDALLARITPTADAADFKGVDFVIEAVFENQELKHK 437 Query: 458 VLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKT 517 V E+E ++ + I SNTS LPI+ +A KR E IG+H+FSPVDKM L+EII EKT Sbjct: 438 VFGEIEDIVEPNAILGSNTSTLPITGLATGVKRQEDFIGIHFFSPVDKMPLVEIIKGEKT 497 Query: 518 SKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTS 577 S + A L GK IVV D GF+T+R + ++E + +L EGV+P ++ + Sbjct: 498 SDEALARVFDYTLAIGKTPIVVNDSRGFFTSRVIGTFVNEALAMLGEGVEPASIEQAGSQ 557 Query: 578 FGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPE----LLTQMVSKGFLGRKSG 633 G+P L DE+ +++ +A K + G P ++ +M+ G GR G Sbjct: 558 AGYPAPPLQLSDELNLELMHKIAVATRKGVEDAGGTYQPHPAEAVVEKMIELGRSGRLKG 617 Query: 634 KGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQEGI 693 GFY Y +G KR L + S P +D+ R++ E CL EG+ Sbjct: 618 AGFYEYADG-KRSGLWPGLRETFKSGSSQPPL-----QDMIDRMLFAEALETQKCLDEGV 671 Query: 694 LATPAEGDIGAVFGLGFPPCLGGPFRFVDLY------GAQKIVDRLKKYEAAYGKQFTPC 747 L + A+ +IG++ G+GFPP GG +F+ Y G V R ++ AAYG +F P Sbjct: 672 LTSTADANIGSIMGIGFPPWTGGSAQFIVGYSGPAGTGKAAFVARARELAAAYGDRFLPP 731 Query: 748 QLL 750 + L Sbjct: 732 ESL 734 >1ZCJ-A nrPDB Length = 463 Score = 479 bits (1233), Expect = e-135, Method: Composition-based stats. Identities = 126/447 (28%), Positives = 210/447 (46%), Gaps = 35/447 (7%) Query: 332 MTKESKALMGLYHGQVLCKKNKFGAP---------QKDVKHLAILGAGLMGAGIAQVSVD 382 + ++KAL + + NK+ P + V + +LG G MG GIA Sbjct: 1 ASGQAKALQYAFFAEK--SANKWSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFAR 58 Query: 383 KGLKTILKDATLTALDRGQQQVFKGLN---DKVKKKALTSFERDSIFSNLTGQLDYQGFE 439 G+ + ++ LD ++ + L + + S + FS+ T +L Sbjct: 59 VGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSSTKELS----- 113 Query: 440 KADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKVIGMHY 499 D+V+EAVFED++LK +V E+ A+ +NTSAL + +IA+ + RP+ VIG H+ Sbjct: 114 TVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCTNTSALNVDDIASSTDRPQLVIGTHF 173 Query: 500 FSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVI 559 FSP M+LLE+I + +S T A+ +++ K GK+ +VV + GF R LAP ++ Sbjct: 174 FSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYGFVGNRMLAPYYNQGF 233 Query: 560 RILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNP--- 616 +L+EG P+ +D + FGF +G + D G+DV + + G + G G P Sbjct: 234 FLLEEGSKPEDVDGVLEEFGFKMGPFRVSDLAGLDVGWKIRKGQG-LTGPSLPPGTPVRK 292 Query: 617 -------ELLTQMVSKGFLGRKSGKGFYIYQEGVKR-KDLNSDMDSILASLKLPPK--SE 666 L + G G+K+GKG+Y Y + + R + + + L+ + Sbjct: 293 RGNSRYSPLGDMLCEAGRFGQKTGKGWYQYDKPLGRIHKPDPWLSTFLSQYREVHHIEQR 352 Query: 667 VSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGA 726 S E+I R + +NEA L+EG+ A P D+ + G G+P GGP + G Sbjct: 353 TISKEEILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGL 412 Query: 727 QKIVDRLKKYEAAYGK--QFTPCQLLA 751 ++++L+KY Q P L Sbjct: 413 PTVLEKLQKYYRQNPDIPQLEPSDYLR 439 Score = 49.3 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 19/87 (21%), Positives = 37/87 (42%), Gaps = 6/87 (6%) Query: 546 YTTRCLAPMMSEVIRILQEG--VDPKKLDSLTT-SFGFPV---GAATLVDEVGVDVAKHV 599 RCL +++E RIL+EG P+ +D + +G+P G VG+ Sbjct: 359 ILERCLYSLINEAFRILEEGMAARPEHIDVIYLHGYGWPRHKGGPMFYAASVGLPTVLEK 418 Query: 600 AEDLGKVFGERFGGGNPELLTQMVSKG 626 + + + + L ++V++G Sbjct: 419 LQKYYRQNPDIPQLEPSDYLRRLVAQG 445 >3K6J-A nrPDB Length = 460 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 108/382 (28%), Positives = 193/382 (50%), Gaps = 14/382 (3%) Query: 360 DVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTS 419 DV +AI+G G MG +A G++T L + R +Q++ + K L Sbjct: 53 DVNSVAIIGGGTMGKAMAICFGLAGIETFLV---VRNEQRCKQELEVMYAREKSFKRLND 109 Query: 420 FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSAL 479 + I +NL D+ D+++E+V ED+ LK + +E + CIF +NTS+L Sbjct: 110 KRIEKINANLKITSDFHKLSNCDLIVESVIEDMKLKKELFANLENICKSTCIFGTNTSSL 169 Query: 480 PISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVV 539 ++EI++V + P ++G+H+F+P + ++L+EII TS A+A K+ ++V Sbjct: 170 DLNEISSVLRDPSNLVGIHFFNPANVIRLVEIIYGSHTSSQAIATAFQACESIKKLPVLV 229 Query: 540 KDGPGFYTTRCLAPMMSEVIRILQE-GVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKH 598 + F R L + +++ E G P ++D + T+FGF +G T+ D G DV + Sbjct: 230 GNCKSFVFNRLLHVYFDQSQKLMYEYGYLPHQIDKIITNFGFLMGPMTVADMNGFDVMEK 289 Query: 599 VAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILAS 658 + ++ G + +M GRK+ KGFY Y + +RK+ +++M+ I+ Sbjct: 290 LKKENGLE--------PNPIEKEMWRLKRYGRKTNKGFYKYDDKTQRKENDTEMEQIIRR 341 Query: 659 LKLPPKSE--VSSDEDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGG 716 + KS + +D+D+ ++ VNE C++EG+++ + DI + G G+P GG Sbjct: 342 VSQNAKSNIQIINDQDVINFMLYPTVNEGYRCIEEGVISNESLIDIMFILGFGWPIHSGG 401 Query: 717 PFRFVDLYGAQKIVDRLKKYEA 738 P RF G KI + L + + Sbjct: 402 PMRFGKTEGLDKIANMLVHWSS 423 >6ACQ-A nrPDB Length = 302 Score = 359 bits (922), Expect = 2e-99, Method: Composition-based stats. Identities = 100/284 (35%), Positives = 161/284 (56%), Gaps = 5/284 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 +K + ++GAG MG+GIAQ KG + +L+D +DRG + K L+ VKK + Sbjct: 21 MKKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEA 80 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 + I + ++G +D D+VIEA E + +K ++ +++ + I ASNTS+L Sbjct: 81 TKVEILTRISGTVDLNMAADCDLVIEAAVERMDIKKQIFADLDNICKPETILASNTSSLS 140 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 I+E+A+ +KRP+KVIGMH+F+P M+L+E+I TS++T + + GK + V Sbjct: 141 ITEVASATKRPDKVIGMHFFNPAPVMKLVEVIRGIATSQETFDAVKETSIAIGKDPVEVA 200 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLD-SLTTSFGFPVGAATLVDEVGVDVAKH 598 + PGF R L PM++E + IL EG+ + +D ++ P+G L D +G+D+ Sbjct: 201 EAPGFVVNRILIPMINEAVGILAEGIASVEDIDKAMKLGANHPMGPLELGDFIGLDICLA 260 Query: 599 VAEDLGKVFGERFGGGNPE-LLTQMVSKGFLGRKSGKGFYIYQE 641 + + L G+ P LL + V G+LGRKSGKGFY Y + Sbjct: 261 IMDVLYSETGD--SKYRPHTLLKKYVRAGWLGRKSGKGFYDYSK 302 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 5/86 (5%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 + R++ +NEAV L EGI A+ + D G P GP D G + Sbjct: 206 VVNRILIPMINEAVGILAEGI-ASVEDIDKAMKLGANHPM---GPLELGDFIGLDICLAI 261 Query: 733 LKKYEAAYGK-QFTPCQLLADHANSP 757 + + G ++ P LL + + Sbjct: 262 MDVLYSETGDSKYRPHTLLKKYVRAG 287 >4KUG-A nrPDB Length = 290 Score = 357 bits (915), Expect = 1e-98, Method: Composition-based stats. Identities = 102/285 (35%), Positives = 161/285 (56%), Gaps = 3/285 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 +K + +LGAG MGAGI Q KG + I++D +DRG + K L+ V K+ +T Sbjct: 1 MKKVFVLGAGTMGAGIVQAFAAKGCEVIVRDIKEEFVDRGIATITKSLSKLVAKEKITEA 60 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 +++ I S ++G D + D+V+EA E++ +K + E++ + I ASNTS+L Sbjct: 61 DKEEILSRISGTTDMKLAADCDLVVEAAIENMKIKKEIFAELDGICKPETILASNTSSLS 120 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 I+E+A+ +KR +KVIGMH+F+P M+L+E+I TS++T + + GK + V Sbjct: 121 ITEVASATKRADKVIGMHFFNPAPVMKLVEVIRGAATSQETFDAVKEMSESIGKTPVEVA 180 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEGVDP-KKLD-SLTTSFGFPVGAATLVDEVGVDVAKH 598 + PGF R L PM++E ILQEGV + +D ++ P+G L D +G+DV Sbjct: 181 EAPGFVVNRILIPMINEATFILQEGVAKEEDIDAAMKLGANHPMGPLALGDLIGLDVCLA 240 Query: 599 VAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGV 643 + + L G+ LL + V G+LGRK+GKGFY Y + Sbjct: 241 IMDVLYNETGDT-KYRASSLLRKYVRAGWLGRKTGKGFYDYSKSK 284 Score = 53.6 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 20/86 (23%), Positives = 32/86 (37%), Gaps = 5/86 (5%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 + R++ +NEA LQEG+ A + D G P GP DL G + Sbjct: 186 VVNRILIPMINEATFILQEGV-AKEEDIDAAMKLGANHPM---GPLALGDLIGLDVCLAI 241 Query: 733 LKKYEAAYGK-QFTPCQLLADHANSP 757 + G ++ LL + + Sbjct: 242 MDVLYNETGDTKYRASSLLRKYVRAG 267 >1F14-A nrPDB Length = 310 Score = 350 bits (899), Expect = 1e-96, Method: Composition-based stats. Identities = 95/288 (32%), Positives = 153/288 (53%), Gaps = 8/288 (2%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK----- 415 VKH+ ++G GLMGAGIAQV+ G +L D T L + ++ + + L KKK Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENP 74 Query: 416 ALTSFERDSIFSNLTGQLDYQGF-EKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 + S + D D+V+EA+ E+L +K+ + K ++ +H IFAS Sbjct: 75 KAGDECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFAS 134 Query: 475 NTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGK 534 NTS+L I+ IA + R ++ G+H+F+PV M+L+E+I T TS+ T S V GK Sbjct: 135 NTSSLQITSIANATTRQDRFAGLHFFNPVPVMKLVEVIKTPMTSQKTFESLVDFSKALGK 194 Query: 535 VIIVVKDGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-SLTTSFGFPVGAATLVDEVG 592 + KD PGF R L P + E IR+ + G + +D ++ G+P+G L+D VG Sbjct: 195 HPVSCKDTPGFIVNRLLVPYLMEAIRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 254 Query: 593 VDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQ 640 +D K + + ++ E L ++V++ G+K+G+GFY Y+ Sbjct: 255 LDTTKFIVDGWHEMDAENPLHQPSPSLNKLVAENKFGKKTGEGFYKYK 302 Score = 46.6 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 I RL+ ++ EA+ + G + + D G G+P GPF +D G Sbjct: 206 IVNRLLVPYLMEAIRLYERGDASKE-DIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 261 Query: 733 LKKY 736 + + Sbjct: 262 VDGW 265 >3HDH-A nrPDB Length = 302 Score = 347 bits (891), Expect = 9e-96, Method: Composition-based stats. Identities = 90/288 (31%), Positives = 154/288 (53%), Gaps = 8/288 (2%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK----- 415 VKH+ ++G GLMGAGIAQV+ G +L D T L + ++ + + L KKK Sbjct: 15 VKHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENP 74 Query: 416 ALTSFERDSIFSNLTGQLDYQGF-EKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 + S+++ D D+V+EA+ E+L +K + K ++ +H IFAS Sbjct: 75 KAGDEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHTIFAS 134 Query: 475 NTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGK 534 NTS+L I+ +A + R ++ G+H+F+PV M+L+E++ T TS+ T S V GK Sbjct: 135 NTSSLQITSLANATTRQDRFAGLHFFNPVPLMKLVEVVKTPMTSQKTLESLVDFSKTLGK 194 Query: 535 VIIVVKDGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-SLTTSFGFPVGAATLVDEVG 592 + KD PGF R L P + E +R+ + G + +D ++ G+P+G L+D VG Sbjct: 195 HPVSCKDTPGFIVNRLLVPYLIEAVRLYERGDASKEDIDTAMKLGAGYPMGPFELLDYVG 254 Query: 593 VDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQ 640 +D K + + ++ + + ++V++ G+K+G+GFY Y+ Sbjct: 255 LDTTKFIIDGWHEMDSQNPLFQPSPAMNKLVAENKFGKKTGEGFYKYK 302 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 26/64 (40%), Gaps = 4/64 (6%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 I RL+ ++ EAV + G + + D G G+P GPF +D G Sbjct: 206 IVNRLLVPYLIEAVRLYERGDASKE-DIDTAMKLGAGYPM---GPFELLDYVGLDTTKFI 261 Query: 733 LKKY 736 + + Sbjct: 262 IDGW 265 >4J0E-A nrPDB Length = 320 Score = 343 bits (880), Expect = 1e-94, Method: Composition-based stats. Identities = 87/290 (30%), Positives = 150/290 (51%), Gaps = 7/290 (2%) Query: 359 KDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALT 418 ++++++AI+G+G MG+GIAQV+ G +L D ALDR + + + + KK+ T Sbjct: 12 QNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHLSKKQKGT 71 Query: 419 SFERDSIFSNLTGQLDY-----QGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFA 473 E+ + ++ AD++IEA E++ LK + ++E I Sbjct: 72 DKEKSDFVTLTMSRIKTCNNVSTAVADADLIIEAAIENIDLKRGIFAQIEQSCKKDSILT 131 Query: 474 SNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQG 533 +NTS+ + ++A + + G+H+F+PV M+LLE+I ++ TS +T A+ + G G Sbjct: 132 TNTSSFLLEDVAKGLQDKTRFGGLHFFNPVPVMKLLEVIRSDDTSDETYATLIKFGTAVG 191 Query: 534 KVIIVVKDGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-SLTTSFGFPVGAATLVDEV 591 K + KD PGF R L P E R+ + G +D ++ G P+G L D + Sbjct: 192 KTTVACKDSPGFIVNRLLIPYFFEAARMYERGDASMTDIDEAMKLGAGHPMGPFELADYI 251 Query: 592 GVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQE 641 G+D K V + + E L+ ++V++G LGRK+G GFY Y++ Sbjct: 252 GLDTVKFVMDGWAAKYPEVQLFEASPLVDKLVAEGKLGRKTGDGFYSYKK 301 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 27/70 (38%), Gaps = 4/70 (5%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 I RL+ + EA + G A+ + D G G P GPF D G + Sbjct: 204 IVNRLLIPYFFEAARMYERG-DASMTDIDEAMKLGAGHPM---GPFELADYIGLDTVKFV 259 Query: 733 LKKYEAAYGK 742 + + A Y + Sbjct: 260 MDGWAAKYPE 269 >3MOG-A nrPDB Length = 483 Score = 337 bits (864), Expect = 1e-92, Method: Composition-based stats. Identities = 98/333 (29%), Positives = 160/333 (48%), Gaps = 4/333 (1%) Query: 360 DVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTS 419 +V+ +A++G+G MGAGIA+V+ G + +L D + AL R + LN +V + LT+ Sbjct: 4 NVQTVAVIGSGTMGAGIAEVAASHGHQVLLYDISAEALTRAIDGIHARLNSRVTRGKLTA 63 Query: 420 FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSAL 479 + L D AD+VIEA E L +K + ++ V P + +NTS++ Sbjct: 64 ETCERTLKRLIPVTDIHALAAADLVIEAASERLEVKKALFAQLAEVCPPQTLLTTNTSSI 123 Query: 480 PISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVV 539 I+ IAA K PE+V G+H+F+P M+L+E+++ T+ + + L GK + Sbjct: 124 SITAIAAEIKNPERVAGLHFFNPAPVMKLVEVVSGLATAAEVVEQLCELTLSWGKQPVRC 183 Query: 540 KDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLD-SLTTSFGFPVGAATLVDEVGVDVAK 597 PGF R P SE R L+E V P+ +D +L GFP+G L D +G DV Sbjct: 184 HSTPGFIVNRVARPYYSEAWRALEEQVAAPEVIDAALRDGAGFPMGPLELTDLIGQDVNF 243 Query: 598 HVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILA 657 V + F + + ++V G LG+KSG G Y ++ + + + Sbjct: 244 AVTCSVFNAFWQERRFLPSLVQQELVIGGRLGKKSGLGVYDWRAEREAVVGLEAVSDSFS 303 Query: 658 SLKLPPKSEVSSDEDIQFRLVTRFVNEAVMCLQ 690 +K+ KS+ + +I L+ E L Sbjct: 304 PMKVEKKSDGVT--EIDDVLLIETQGETAQALA 334 Score = 90.6 bits (223), Expect = 3e-18, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 + +R V +NEA+ LQ+G+ A+ + D G+ +P GP + G Q+I+ Sbjct: 389 LIWRTVAMIINEALDALQKGV-ASEQDIDTAMRLGVNYP---YGPLAWGAQLGWQRILRL 444 Query: 733 LKKYEAAYG-KQFTPCQLLADHA 754 L+ + YG +++ PC LL A Sbjct: 445 LENLQHHYGEERYRPCSLLRQRA 467 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 41/204 (20%), Positives = 83/204 (40%), Gaps = 18/204 (8%) Query: 431 GQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPISEIAAVSKR 490 G D++ +A + +EAV + S +V K+ + V + T +A R Sbjct: 281 GVYDWRAEREAVVGLEAVSDSFS-PMKVEKKSDGVTEIDDVLLIETQGETAQALAIRLAR 339 Query: 491 P----EKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDGPGFY 546 P +K+ G +++ I + A+ +QGK ++ + D PG Sbjct: 340 PVVVIDKMAG----------KVVTIAAAAVNPDSATRKAIYYLQQQGKTVLQIADYPGML 389 Query: 547 TTRCLAPMMSEVIRILQEGVDPK-KLD-SLTTSFGFPVGAATLVDEVGVDVAKHVAEDLG 604 R +A +++E + LQ+GV + +D ++ +P G ++G + E+L Sbjct: 390 IWRTVAMIINEALDALQKGVASEQDIDTAMRLGVNYPYGPLAWGAQLGWQRILRLLENLQ 449 Query: 605 KVFGERFGGGNPELLTQ-MVSKGF 627 +GE L + ++ G+ Sbjct: 450 HHYGEERYRPCSLLRQRALLESGY 473 >4PZE-A nrPDB Length = 284 Score = 336 bits (862), Expect = 2e-92, Method: Composition-based stats. Identities = 101/283 (35%), Positives = 165/283 (58%), Gaps = 3/283 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 ++ + I+GAG MG GIAQ GL ++ D + A+ +G V L+ +KK+ LT Sbjct: 3 IRTVGIVGAGTMGNGIAQACAVVGLNVVMVDISDAAVQKGVATVASSLDRLIKKEKLTEA 62 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALP 480 ++ S + + G Y + D+VIEA E+ LK ++LK+++ ++ ++ I ASNTS++ Sbjct: 63 DKASALARIKGSTSYDDLKATDIVIEAATENYDLKVKILKQIDGIVGENVIIASNTSSIS 122 Query: 481 ISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVK 540 I+++AAV+ R ++ IGMH+F+PV M L+E+I +TS T A+ A+ + GK I VK Sbjct: 123 ITKLAAVTSRADRFIGMHFFNPVPVMALVELIRGLQTSDTTHAAVEALSKQLGKYPITVK 182 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-SLTTSFGFPVGAATLVDEVGVDVAKH 598 + PGF R L PM++E +L EG P+++D + P+G L D +G+D Sbjct: 183 NSPGFVVNRILCPMINEAFCVLGEGLASPEEIDEGMKLGCNHPIGPLALADMIGLDTMLA 242 Query: 599 VAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQE 641 V E L F + L+ +MV+ G+LGRK+G+G Y+Y + Sbjct: 243 VMEVLYTEFAD-PKYRPAMLMREMVAAGYLGRKTGRGVYVYSK 284 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 37/86 (43%), Gaps = 5/86 (5%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDR 732 + R++ +NEA L EG LA+P E D G G P GP D+ G ++ Sbjct: 188 VVNRILCPMINEAFCVLGEG-LASPEEIDEGMKLGCNHPI---GPLALADMIGLDTMLAV 243 Query: 733 LKKYEAAYGK-QFTPCQLLADHANSP 757 ++ + ++ P L+ + + Sbjct: 244 MEVLYTEFADPKYRPAMLMREMVAAG 269 >6HRD-A nrPDB Length = 317 Score = 310 bits (795), Expect = 1e-84, Method: Composition-based stats. Identities = 92/296 (31%), Positives = 156/296 (52%), Gaps = 5/296 (1%) Query: 353 KFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKV 412 + ++ + ++GAG MG+GIA+VS G++ + + + G+ ++ K L V Sbjct: 17 RGSHMSDAIQRVGVVGAGQMGSGIAEVSARAGVEVTVFEPAEALITAGRNRIVKSLERAV 76 Query: 413 KKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVI-PDHCI 471 +T ERD LT D +VIEAV ED ++K + E++ V+ + Sbjct: 77 SAGKVTERERDRALGLLTFTTDLNDLSDRQLVIEAVVEDEAVKSEIFAELDRVVTDPDAV 136 Query: 472 FASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLK 531 ASNTS++PI ++AA +K+P++V+G+H+F+PV + L+E++ T T + +A Sbjct: 137 LASNTSSIPIMKVAAATKQPQRVLGLHFFNPVPVLPLVELVRTLVTDEAAAARTEEFAST 196 Query: 532 -QGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-SLTTSFGFPVGAATLV 588 GK ++ D GF L P + IR+++ G + +D ++ P+G L Sbjct: 197 VLGKQVVRCSDRSGFVVNALLVPYLLSAIRMVEAGFATVEDVDKAVVAGLSHPMGPLRLS 256 Query: 589 DEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVK 644 D VG+D K +A+ + + F E G P LL +MV G LG+KSG+GFY Y ++ Sbjct: 257 DLVGLDTLKLIADKMFEEFKEPH-YGPPPLLLRMVEAGQLGKKSGRGFYTYAAALE 311 >4OM8-A nrPDB Length = 309 Score = 266 bits (681), Expect = 2e-71, Method: Composition-based stats. Identities = 82/291 (28%), Positives = 145/291 (49%), Gaps = 22/291 (7%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQ------QQVFKGLNDKVKK 414 ++++AI+G G MG G+A GL+ + D A++R + + V L + Sbjct: 2 IRNIAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPS 61 Query: 415 KALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 + + AD+VIE V E++S+K V + ++ +I I AS Sbjct: 62 AGVGTVRFTDDIG--------DAVSGADLVIENVPENISIKADVYRTIDGLIGQDTIVAS 113 Query: 475 NTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGK 534 +TS +PI+++ A PE+++GMH+ +P + ++E+I EKT+ T A+ + G Sbjct: 114 DTSGIPITKLQAHISYPERMVGMHWSNPPHIIPMIEVIAGEKTAPQTVATIRDLIRSIGL 173 Query: 535 VIIVV-KDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLDS-LTTSFGFP---VGAATLV 588 + +VV KD PGF R L ++ E + +++ GV DP+ LD+ ++ G+ +G L+ Sbjct: 174 LPVVVKKDVPGFVENRVLYALLREAVDLVERGVIDPEDLDTCVSWGIGYKIAVIGPMALL 233 Query: 589 DEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIY 639 D G+D+ K V+ L R P +L + + G KSG+G + Y Sbjct: 234 DMAGLDIYKSVSSFLNADLSNR-DDVAPMVLEKTSAS-KFGIKSGEGMFCY 282 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 39/80 (48%), Gaps = 8/80 (10%) Query: 652 MDSILASLKLPPKSEVSSDEDI----QFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFG 707 + ++ S+ L P V +D+ + R++ + EAV ++ G++ P + D +G Sbjct: 164 IRDLIRSIGLLP---VVVKKDVPGFVENRVLYALLREAVDLVERGVI-DPEDLDTCVSWG 219 Query: 708 LGFPPCLGGPFRFVDLYGAQ 727 +G+ + GP +D+ G Sbjct: 220 IGYKIAVIGPMALLDMAGLD 239 >4DYD-A nrPDB Length = 283 Score = 266 bits (680), Expect = 3e-71, Method: Composition-based stats. Identities = 76/285 (26%), Positives = 131/285 (45%), Gaps = 11/285 (3%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++ +LG G++G+ IA + G D ALD +++ F+GL +K+ + Sbjct: 4 ITNVTVLGTGVLGSQIAFQTAFHGFAVTAYDINTDALDAAKKR-FEGLAAVYEKEVAGAA 62 Query: 421 E--RDSIFSNLTGQLD-YQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTS 477 + + D Q + AD+VIEAV E L LK + ++ + P IFA+N+S Sbjct: 63 DGAAQKALGGIRYSDDLAQAVKDADLVIEAVPESLDLKRDIYTKLGELAPAKTIFATNSS 122 Query: 478 ALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVII 537 L S++ + R +K + +H+ + V E++ T KT + V G V I Sbjct: 123 TLLPSDLVGYTGRGDKFLALHFANHVWVNNTAEVMGTTKTDPEVYQQVVEFASAIGMVPI 182 Query: 538 VV-KDGPGFYTTRCLAPMMSEVIRILQEGV-DPKKLDS-LTTSFGFPVGAATLVDEVGVD 594 + K+ G+ L P++ +L +G+ DP+ +D G P G + D VG+ Sbjct: 183 ELKKEKAGYVLNSLLVPLLDAAAELLVDGIADPETIDKTWRIGTGAPKGPFEIFDIVGLT 242 Query: 595 VAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIY 639 A +++ V G + L + KG LG +G+GFY Y Sbjct: 243 TAYNIS----SVSGPKQREFAAYLKENYIDKGKLGLATGEGFYRY 283 >1ZEJ-A nrPDB Length = 293 Score = 261 bits (668), Expect = 6e-70, Method: Composition-based stats. Identities = 84/281 (29%), Positives = 139/281 (49%), Gaps = 27/281 (9%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 + ++GAGLMG GIA K + +L+D + AL+ ++Q+ + L Sbjct: 14 KVFVIGAGLMGRGIAIAIASK-HEVVLQDVSEKALEAAREQIPEEL-------------- 58 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPIS 482 S + + + D+V+EAVFEDL+ K VL+EVE + + SNTS + + Sbjct: 59 ---LSKIEFTTTLEKVKDCDIVMEAVFEDLNTKVEVLREVERLT--NAPLCSNTSVISVD 113 Query: 483 EIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKDG 542 +IA P + +G+H+ +P M L+EI+ + T T A + GK ++V K Sbjct: 114 DIAERLDSPSRFLGVHWMNPPHVMPLVEIVISRFTDSKTVAFVEGFLRELGKEVVVCKGQ 173 Query: 543 PGFYTTRCLAPMMSEVIRILQEGVDPKKLDSL---TTSFGFPV-GAATLVDEVGVDVAKH 598 R A ++SE R+++EGV + +D + + + G +D +G+DVA + Sbjct: 174 S--LVNRFNAAVLSEASRMIEEGVRAEDVDRVWKHHLGLLYTLFGPLGNLDYIGLDVAYY 231 Query: 599 VAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIY 639 + L K FG+ PE L + + KG +G K+GKG Y Y Sbjct: 232 ASLYLYKRFGDE-KFKPPEWLQEKIKKGEVGVKAGKGIYEY 271 Score = 45.1 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 31/89 (34%), Gaps = 3/89 (3%) Query: 671 EDIQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIV 730 + + R ++EA ++EG+ + D LG L GP +D G Sbjct: 173 QSLVNRFNAAVLSEASRMIEEGV--RAEDVDRVWKHHLGLLYTLFGPLGNLDYIGLDVAY 230 Query: 731 DRLKKYEAAYG-KQFTPCQLLADHANSPN 758 +G ++F P + L + Sbjct: 231 YASLYLYKRFGDEKFKPPEWLQEKIKKGE 259 >3F3S-A nrPDB Length = 313 Score = 251 bits (641), Expect = 8e-67, Method: Composition-based stats. Identities = 66/279 (23%), Positives = 120/279 (43%), Gaps = 16/279 (5%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL-TSFER 422 + I+G+G++G A + G + L D + + + K + + +L S Sbjct: 6 VVIVGSGVIGRSWAMLFASGGFQVKLYDIEQQQIRNALENIRKEMKLLEQAGSLKGSLSV 65 Query: 423 DSIFSNLTGQLDYQ-GFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPI 481 + S ++G + Q E A + E V EDL LK ++ +++++I D I +S+TS L Sbjct: 66 EEQLSLISGCPNIQEAVEGAMHIQECVPEDLELKKKIFAQLDSIIDDRVILSSSTSCLMP 125 Query: 482 SEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVV-K 540 S++ A ++ I H +P + L+E++ +T+ T A+ K G+ + V K Sbjct: 126 SKLFAGLVHVKQCIVAHPVNPPYYIPLVELVPHPETAPTTVDRTHALMKKIGQCPMRVQK 185 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEG-VDPKKLD-----SLTTSFGF--PVGAATLVDEVG 592 + GF R ++SE R+++EG V P LD L + F P+ L E Sbjct: 186 EVAGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGM 245 Query: 593 VDVAKHVAEDLGKVFG-----ERFGGGNPELLTQMVSKG 626 + +E + V F E + Q + Sbjct: 246 LSYCDRYSEGIKHVLQTFGPIPEFSRATAEKVNQDMCMK 284 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 3/76 (3%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFR--FVDLYGAQKIV 730 + RL ++EA ++EGI+ +P++ D+ GLG GP ++ G Sbjct: 191 VLNRLQYAIISEAWRLVEEGIV-SPSDLDLVMSEGLGMRYAFIGPLETMHLNAEGMLSYC 249 Query: 731 DRLKKYEAAYGKQFTP 746 DR + + F P Sbjct: 250 DRYSEGIKHVLQTFGP 265 >3ADO-A nrPDB Length = 319 Score = 232 bits (591), Expect = 5e-61, Method: Composition-based stats. Identities = 62/279 (22%), Positives = 121/279 (43%), Gaps = 16/279 (5%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL-TSFER 422 + I+G+GL+G A + G + L D + + + K + + +L S Sbjct: 9 VLIVGSGLVGRSWAMLFASGGFRVKLYDIEPRQITGALENIRKEMKSLQQSGSLKGSLSA 68 Query: 423 DSIFSNLTGQLD-YQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPI 481 + S ++ + + E + E V E+L LK ++ ++++++ D + +S++S L Sbjct: 69 EEQLSLISSCTNLAEAVEGVVHIQECVPENLDLKRKIFAQLDSIVDDRVVLSSSSSCLLP 128 Query: 482 SEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVII-VVK 540 S++ ++ I H +P + L+E++ +TS T A+ K G+ + V+K Sbjct: 129 SKLFTGLAHVKQCIVAHPVNPPYYIPLVELVPHPETSPATVDRTHALMRKIGQSPVRVLK 188 Query: 541 DGPGFYTTRCLAPMMSEVIRILQEG-VDPKKL-----DSLTTSFGF--PVGAATLVDEVG 592 + GF R ++SE R+++EG V P L D L + F P+ L E Sbjct: 189 EIDGFVLNRLQYAIISEAWRLVEEGIVSPSDLDLVMSDGLGMRYAFIGPLETMHLNAEGM 248 Query: 593 VDVAKHVAEDLGKVFG-----ERFGGGNPELLTQMVSKG 626 + +E + +V F G E + Q + K Sbjct: 249 LSYCDRYSEGMKRVLKSFGSIPEFSGATVEKVNQAMCKK 287 Score = 38.9 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 24/47 (51%), Gaps = 1/47 (2%) Query: 673 IQFRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFR 719 + RL ++EA ++EGI+ +P++ D+ GLG GP Sbjct: 194 VLNRLQYAIISEAWRLVEEGIV-SPSDLDLVMSDGLGMRYAFIGPLE 239 >5ZAI-A nrPDB Length = 259 Score = 209 bits (532), Expect = 4e-54, Method: Composition-based stats. Identities = 78/220 (35%), Positives = 125/220 (56%), Gaps = 10/220 (4%) Query: 36 LTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKP 95 + I +G++ + +N P+ K+N L+ +L E +++ + +IR ++I+ K Sbjct: 1 MEFETIETKKEGNLFWITLNRPD-KLNALNAKLLEELDRAVSQAESDPEIR-VIIITGKG 58 Query: 96 GCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAIS 155 F AGADI T E + S++ + I++K+E +KP +A ING LGGGLE+A++ Sbjct: 59 KAFCAGADITQFNQL-TPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALA 117 Query: 156 CQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKM 215 C RIA ++ + LG PE+ LG PG GGTQRL +++G AL+MM+TG I A+K Sbjct: 118 CDIRIAAEEAQ--LGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKY 175 Query: 216 GLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK 255 GLV+++V L E+ T + E++A LA K Sbjct: 176 GLVNRVVP-----LANLEQETRKLAEKIAKKSPISLALIK 210 >2IEX-A nrPDB Length = 272 Score = 209 bits (531), Expect = 5e-54, Method: Composition-based stats. Identities = 51/271 (18%), Positives = 98/271 (36%), Gaps = 13/271 (4%) Query: 34 ALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISS 93 I Y +A + IN P N + +E + + I +L + Sbjct: 7 KQYDYEDIIYETYNGIAKITINRPEV-HNAFRPKTVNEMIDAFTKARDDSNIGVIILTGA 65 Query: 94 KPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVA 153 F +G D + + E + + KP++A + G +GGG + Sbjct: 66 GGKAFCSGGDQKVRGHGGYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLH 125 Query: 154 ISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAK 213 + C IA + + G +G+ G G L ++VG A ++ R A A Sbjct: 126 VVCDLTIAADNA--IFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEAL 183 Query: 214 KMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAM 273 +MGLV+++V L+ EE T+++ +E+ + K + D + + A Sbjct: 184 EMGLVNKVVP-----LEQLEEETVKWAQEILEKSPTAIRFLKAAFNADSDGLAGIQQLAG 238 Query: 274 TIPFV-----RQQVYKKVEEKVRKQTKGLYP 299 + + + ++ RK +P Sbjct: 239 DATLLFYTTEEAKEGMRAFKEKRKPDFSQFP 269 >5Z7R-A nrPDB Length = 267 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 76/236 (32%), Positives = 127/236 (53%), Gaps = 9/236 (3%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + +G VAVV IN P + +N L+ + E V+ EI ++ + +L + F+A Sbjct: 6 VILEKEGKVAVVTINRPKA-LNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSFVA 64 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 GADI+ + T++ + ++ +LE KP++AA+NG LGGG E+A+SC RI Sbjct: 65 GADISEMKEMNTIEG-RKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIRI 123 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 A+ + + G PEV LG PG GGTQRL ++VG+ A ++ T ++I+AD A ++GLV++ Sbjct: 124 ASSNAR--FGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNK 181 Query: 221 LVEPLGPGLKPPEERTIEYLEE---VAITFAKGLADKKISPKRDKGLVEKLTAYAM 273 +VEP L + + VA+ +K ++ + D L + A+ Sbjct: 182 VVEP--SELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGE 235 >3T88-A nrPDB Length = 289 Score = 203 bits (515), Expect = 3e-52, Method: Composition-based stats. Identities = 49/252 (19%), Positives = 88/252 (34%), Gaps = 14/252 (5%) Query: 47 GDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINM 106 +A + IN P + N E + + + D I +L + F +G D + Sbjct: 36 DGIAKITINRPQVR-NAFRPLTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKV 94 Query: 107 LAA-CKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 + ++ KP+VA + G +GGG + + C IA + Sbjct: 95 RGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNA 154 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPL 225 + G +G+ G G + ++VG A ++ R A +A MGLV+ +V Sbjct: 155 --IFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGLVNTVVP-- 210 Query: 226 GPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFV-----RQ 280 L E+ T+ + E+ L K + D L A + Sbjct: 211 ---LADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELAGNATMLFYMTEEG 267 Query: 281 QVYKKVEEKVRK 292 Q + + R+ Sbjct: 268 QEGRNAFNQKRQ 279 >4JCS-A nrPDB Length = 286 Score = 197 bits (500), Expect = 2e-50, Method: Composition-based stats. Identities = 62/271 (22%), Positives = 121/271 (44%), Gaps = 24/271 (8%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 +++ V +V +R+N +K N EL ++ V+ + IR ++++S PG F A Sbjct: 26 LDFEVVNNVGWIRMNRA-AKHNPFDAELRADLMTVLERVRDDADIR-VLVLTSHPGSFCA 83 Query: 101 GADINMLAACKTLQEVTQLSQE----AQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 G ++++L L Q+ R + + +P++AA++G G G ++++ Sbjct: 84 GGNLHVLR--DNLDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFALSLTA 141 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 +A+ + + LG +P G LP+ VG+ A ++M + R + A+ A ++G Sbjct: 142 DIVLASP--RARFSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLG 199 Query: 217 LVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK----ISPKRDKGLVEKLTAYA 272 LV ++ E + E+R E E + LA K +S D+ + L A + Sbjct: 200 LVMEVHES-----EALEQRAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLEAAS 254 Query: 273 MTIPFVRQQVYKKVEEKVRKQTKGLYPAPLK 303 F ++ +E + KQ P P + Sbjct: 255 QAAAFSTKEPRAAIEALLSKQ-----PPPFR 280 >2UZF-A nrPDB Length = 273 Score = 196 bits (499), Expect = 2e-50, Method: Composition-based stats. Identities = 50/245 (20%), Positives = 89/245 (36%), Gaps = 8/245 (3%) Query: 34 ALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISS 93 L I Y +A V IN P + N + + +E + + + VL Sbjct: 8 TLREYDEIKYEFYEGIAKVTINRPEVR-NAFTPKTVAEMIDAFSRARDDQNVSVIVLTGE 66 Query: 94 KPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVA 153 F +G D + E + + KP++A + G +GGG + Sbjct: 67 GDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLN 126 Query: 154 ISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAK 213 + C IA + + G +G+ G+ L ++VG A ++ R A A Sbjct: 127 VVCDLTIAADNA--IFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEAL 184 Query: 214 KMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAM 273 MGLV+ +V L+ E+ T+++ +E+ L K + D + L A Sbjct: 185 DMGLVNTVVP-----LEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAG 239 Query: 274 TIPFV 278 + Sbjct: 240 DATLL 244 >5WYB-B nrPDB Length = 280 Score = 196 bits (499), Expect = 3e-50, Method: Composition-based stats. Identities = 73/283 (25%), Positives = 118/283 (41%), Gaps = 16/283 (5%) Query: 24 YICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASD 83 Y +F + L H G A++ IN P + NT ++ +++ + D Sbjct: 8 YKASSFDDTHKLTVEKH------GHTALITINHPPA--NTWDRDSLIGLRQLIEHLNRDD 59 Query: 84 QIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAING 143 I + V+ P F AGAD+NM A + ++++ E L +AAING Sbjct: 60 DIYALVVTGQGPKFFSAGADLNMFADGDKAR-AREMARRFGEAFEALRDFRGVSIAAING 118 Query: 144 SCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLT 203 +GGGLE A++C RIA +R+ + PE +G LP AGGTQ LP +VG A M+L Sbjct: 119 YAMGGGLECALACDIRIA--ERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILC 176 Query: 204 GRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKG 263 + A+ A ++GLV+Q+V+ + +VA + K + + Sbjct: 177 NERVDAETALRIGLVEQVVDSGEA-----RGAALLLAAKVARQSPVAIRTIKPLIQGARE 231 Query: 264 LVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIID 306 FV + E V + P ++ Sbjct: 232 RAPNTWLPEERERFVDLFDAQDTREGVNAFLEKRDPKWRNCLE 274 >3H81-A nrPDB Length = 278 Score = 193 bits (490), Expect = 3e-49, Method: Composition-based stats. Identities = 70/252 (27%), Positives = 113/252 (44%), Gaps = 8/252 (3%) Query: 36 LTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKP 95 +T I V ++ +N P + +N L+ ++ +E + E+ I A++I+ Sbjct: 22 MTYETILVERDQRVGIITLNRPQA-LNALNSQVMNEVTSAATELDDDPDI-GAIIITGSA 79 Query: 96 GCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAIS 155 F AGADI +A L + + KL P +AA+ G LGGG E+A+ Sbjct: 80 KAFAAGADIKEMA---DLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMM 136 Query: 156 CQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKM 215 C IA K G PE+ LG LPG GG+QRL + +G A+D++LTGR++ A A++ Sbjct: 137 CDVLIAADTAK--FGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERS 194 Query: 216 GLVDQLVEPLGPGLKPPE-ERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMT 274 GLV ++V + TI + A AK ++ +GL+ + + Sbjct: 195 GLVSRVVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSA 254 Query: 275 IPFVRQQVYKKV 286 Q Sbjct: 255 FATEDQSEGMAA 266 >4EML-A nrPDB Length = 275 Score = 192 bits (488), Expect = 5e-49, Method: Composition-based stats. Identities = 50/272 (18%), Positives = 106/272 (38%), Gaps = 16/272 (5%) Query: 38 RTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG- 96 I Y G +A + IN P+ K N + E + ++I +L + P Sbjct: 9 YDDILYYKAGGIAKIVINRPH-KRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHS 67 Query: 97 ----CFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEV 152 F +G D ++ + + + + K ++A + G +GGG + Sbjct: 68 DGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVL 127 Query: 153 AISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRA 212 + C IA + + G +G+ G G+ L ++VG A ++ R A A Sbjct: 128 HLVCDLTIAADNA--IFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEA 185 Query: 213 KKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRD---KGLVEKLT 269 ++MG+V+ +V + EE I++ +E+ + K + D + +++L Sbjct: 186 ERMGMVNTVVP-----VDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELA 240 Query: 270 AYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAP 301 A + ++ ++ + + + K+ P Sbjct: 241 GNATLLYYMTEEGSEGKQAFLEKRPPDFSQYP 272 >2HW5-A nrPDB Length = 286 Score = 189 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 73/254 (28%), Positives = 119/254 (46%), Gaps = 9/254 (3%) Query: 44 GVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD 103 G V ++++N P + +N L L E ++ + +I+ D A++++ F AGAD Sbjct: 38 GKNNTVGLIQLNRPKA-LNALCDGLIDELNQAL-KIFEEDPAVGAIVLTGGDKAFAAGAD 95 Query: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 I + + L S + + + L + KP++AA+NG GGG E+A+ C A Sbjct: 96 IKEM---QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA-- 150 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL-- 221 K PE+L+G +PGAGGTQRL + VG A++M+LTG I A AK+ GLV ++ Sbjct: 151 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICP 210 Query: 222 VEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQ 281 VE L E+ + V + + + +EK Y+ R++ Sbjct: 211 VETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE 270 Query: 282 VYKKVEEKVRKQTK 295 EK + K Sbjct: 271 GMTAFVEKRKANFK 284 >2DUB-A nrPDB Length = 261 Score = 189 bits (480), Expect = 4e-48, Method: Composition-based stats. Identities = 67/210 (31%), Positives = 105/210 (50%), Gaps = 20/210 (9%) Query: 44 GVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD 103 G V ++++N P + +N L L E ++ + + A++++ F AGAD Sbjct: 13 GKNSSVGLIQLNRPKA-LNALCNGLIEELNQALETFEEDPAV-GAIVLTGGEKAFAAGAD 70 Query: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 I + + S + + + + KP++AA+NG LGGG E+A+ C A Sbjct: 71 IKEM---QNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMCDIIYA-- 125 Query: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVE 223 K G PE+LLG +PGAGGTQRL + VG A++M+LTG I A AK+ GLV ++ Sbjct: 126 GEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIFP 185 Query: 224 PLGPGLKPPEERTIEYLEEVAITFAKGLAD 253 +E L E AI A+ +A+ Sbjct: 186 -------------VETLVEEAIQCAEKIAN 202 >2PPY-A nrPDB Length = 265 Score = 189 bits (479), Expect = 4e-48, Method: Composition-based stats. Identities = 65/222 (29%), Positives = 117/222 (52%), Gaps = 9/222 (4%) Query: 36 LTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKP 95 + ++ + +A + ++ +K N+ E + EF+ +++I I+ +++S P Sbjct: 6 TKKQYLTVFKEDGIAEIHLH--INKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVP 63 Query: 96 GCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAIS 155 F AGADIN L + + TQ ++K+ +S + +A + G +GGGLE+A++ Sbjct: 64 KFFSAGADINFLRSADP-RFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMALA 122 Query: 156 CQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKM 215 C R + +G PEV LG L G GGTQRL +++G ALDM +TG +I A ++ Sbjct: 123 CDLRFMGDEAG-KIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEI 181 Query: 216 GLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKIS 257 GLV+++ ERT EY ++A + +++ K++ Sbjct: 182 GLVNRVFPQ-----AETRERTREYARKLANSATYAVSNIKLA 218 >3MOY-A nrPDB Length = 263 Score = 185 bits (469), Expect = 6e-47, Method: Composition-based stats. Identities = 76/245 (31%), Positives = 117/245 (47%), Gaps = 10/245 (4%) Query: 31 GSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVL 90 GS T + V G V ++R++ P++ +N L++ L +E + + A +I A++ Sbjct: 3 GSMTTYTTIATSRPVAG-VGLIRLDRPDA-LNALNQTLEAEVLDAARDFDADLEI-GAIV 59 Query: 91 ISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGL 150 ++ F AGADI + TL + + L + KPIVAA+ G LGGG Sbjct: 60 VTGSERAFAAGADIAEMV---TLTPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGC 116 Query: 151 EVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRAD 210 E+A+ C IA + G PE+ LG LPG GGTQRL + VG A+D+ LTGRS+ A+ Sbjct: 117 ELAMLCDLVIAADTAR--FGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAE 174 Query: 211 RAKKMGLVDQLVEP--LGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKL 268 A+++GLV ++V L +R + + P E+ Sbjct: 175 EAERVGLVSRIVPAADLLDEALAVAQRIARMSRPAGRAVKDAINEAFERPLSAGMRYERD 234 Query: 269 TAYAM 273 YAM Sbjct: 235 AFYAM 239 >4FZW-A nrPDB Length = 258 Score = 181 bits (459), Expect = 1e-45, Method: Composition-based stats. Identities = 69/261 (26%), Positives = 127/261 (48%), Gaps = 19/261 (7%) Query: 37 TRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG 96 + + + + V ++ +N P ++ N L+ L + + E A+D S +I+ Sbjct: 3 SMSELIVSRQQRVLLLTLNRPAAR-NALNNALLMQLVNEL-EAAATDTSISVCVITGNAR 60 Query: 97 CFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 F AGAD+N +A L+ ++ +L+ KP++AA+NG LG G E+A+ C Sbjct: 61 FFAAGADLNEMAEKDLAA---TLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLC 117 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 +A ++ + G PE+ LG +PGAGGTQRL + VG A M+L+G SI A +A++ G Sbjct: 118 DVVVAGENAR--FGLPEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAG 175 Query: 217 LVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIP 276 LV + P + T+EY ++A A+ ++ + K + + A+ Sbjct: 176 LVSDVF---------PSDLTLEYALQLASKMARH---SPLALQAAKQALRQSQEVALQAG 223 Query: 277 FVRQQVYKKVEEKVRKQTKGL 297 +++ + + +G+ Sbjct: 224 LAQERQLFTLLAATEDRHEGI 244 >5JBW-A nrPDB Length = 260 Score = 178 bits (452), Expect = 7e-45, Method: Composition-based stats. Identities = 72/231 (31%), Positives = 115/231 (49%), Gaps = 5/231 (2%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 +G + + I+ S+ N +S+ + E E++ + +S +R+ V+ + F AGAD+ Sbjct: 11 RGPIEIWTIDG-ESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLK 69 Query: 106 MLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 A EV +R +EKS +AAING+ LGGG E+A++C R+A Sbjct: 70 ERATMAE-DEVRAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAPAA 128 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV-EP 224 + LG EV LG +PG GGTQRL ++VG A D++LT R I A A +GL ++L E Sbjct: 129 E--LGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEG 186 Query: 225 LGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTI 275 + ++ +A+ AK D+ + D L +L Y + Sbjct: 187 HLLAVAYGLAESVVENAPIAVATAKHAIDEGTGLELDDALALELRKYEEIL 237 >5YLO-A nrPDB Length = 271 Score = 174 bits (442), Expect = 9e-44, Method: Composition-based stats. Identities = 66/261 (25%), Positives = 112/261 (42%), Gaps = 32/261 (12%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + V+ +A + +N P + N L ++ +R AV++ F A Sbjct: 7 LQTRVEAGIAWLVLNRPQQR-NALDIPTLEALHVRLDACERDPAVR-AVVLGGSGRSFCA 64 Query: 101 GADINMLAACKTLQEVTQ--LSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQY 158 GAD+ AA + E+ ++ A ++ +L KP VAA+NGS +G G+++A+ C + Sbjct: 65 GADLAEWAAAEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDF 124 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV 218 RIA + G + P AG + LP+++G AA ++ + A+RA GLV Sbjct: 125 RIAAASARFKAGYTGMAY--CPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLV 182 Query: 219 DQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFV 278 ++V E+L E FA LA A+A T + Sbjct: 183 GEVV-------------ADEHLVEAVGAFAARLASGPT------------FAFAQTKRLL 217 Query: 279 RQQVYKKVEEKVR-KQTKGLY 298 R + + E++R +Q GL Sbjct: 218 RDGAGRSLAEQLRAEQAAGLL 238 >4JWV-A nrPDB Length = 278 Score = 174 bits (440), Expect = 2e-43, Method: Composition-based stats. Identities = 61/215 (28%), Positives = 102/215 (47%), Gaps = 13/215 (6%) Query: 31 GSSALL--TRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSA 88 G+ L + I++ ++G VA VR+N P +N +++E+ + E+ A+ I + Sbjct: 14 GTENLYFQSMADIDFRIEGHVAHVRLNRPQG-LNAITQEMDDLLLDAWTEVNANSDIWAV 72 Query: 89 VLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGG 148 VL + F GAD++ A KT L I L KP+VAA+ G C+GG Sbjct: 73 VLSAEGEKAFCIGADVSGGAERKTR---MALGGGLTGIGGPLVTCKKPMVAAVQGFCVGG 129 Query: 149 GLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIR 208 G E+A+ +A + G PE +G + G R + + AL ++LTG I+ Sbjct: 130 GFELAMCADIIVAADTAQ--FGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIK 187 Query: 209 ADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEV 243 AD A+ GLV+++V EE + + ++ Sbjct: 188 ADEARHYGLVNEVVP-----FAELEEAALRWASKL 217 >6OJM-A nrPDB Length = 286 Score = 172 bits (435), Expect = 6e-43, Method: Composition-based stats. Identities = 44/220 (20%), Positives = 83/220 (37%), Gaps = 13/220 (5%) Query: 38 RTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG- 96 I Y VA + N P + N + SE + + + I +L P Sbjct: 18 YEDITYKKCNGVARIAFNRPEIR-NAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPSP 76 Query: 97 -----CFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLE 151 F +G D + E + + + K ++A + G +GGG Sbjct: 77 KDGGWAFCSGGDQKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGGGHS 136 Query: 152 VAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADR 211 + + C +A+K+ + + + + G G+ L KMVG A ++ GR+ A Sbjct: 137 LHVVCDLTLASKEH-AIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQE 195 Query: 212 AKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGL 251 A +MG+V+++V E+ E+ +E+ + Sbjct: 196 AFEMGMVNKVVPH-----AELEDTAYEWAQEILAKSPTSI 230 >1EF9-A nrPDB Length = 261 Score = 169 bits (429), Expect = 3e-42, Method: Composition-based stats. Identities = 52/222 (23%), Positives = 96/222 (43%), Gaps = 20/222 (9%) Query: 36 LTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLIS-SK 94 ++ ++N VAV+ N K+N LSK + + ++++ +IR +L + S Sbjct: 1 MSYQYVNVVTINKVAVIEFNY-GRKLNALSKVFIDDLMQALSDL-NRPEIRCIILRAPSG 58 Query: 95 PGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAI 154 F AG DI+ L + ++ ++I ++K KPI++ + GS GG E+ + Sbjct: 59 SKVFSAGHDIHELPSGG--RDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIM 116 Query: 155 SCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKK 214 S IA + V LG G L + G +++ T I A RA Sbjct: 117 SSDLIIAAST--STFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALA 174 Query: 215 MGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKI 256 +G+++ +VE +E LE+ + A +++K Sbjct: 175 VGILNHVVE-------------VEELEDFTLQMAHHISEKAP 203 >1NZY-B nrPDB Length = 269 Score = 169 bits (429), Expect = 3e-42, Method: Composition-based stats. Identities = 54/224 (24%), Positives = 97/224 (43%), Gaps = 21/224 (9%) Query: 38 RTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGC 97 I + V+ VA + I P + N LS + E ++ +N D + AV+I+ Sbjct: 2 YEAIGHRVEDGVAEITIKLPRHR-NALSVKAMQEVTDALNRAEEDDSV-GAVMITGAEDA 59 Query: 98 FIAGADINMLAACKTLQEVTQLSQE----AQRIVEKLEKSTKPIVAAINGSCLGGGLEVA 153 F AG + + K + V + +++ K+ + +P++AAING GGGL ++ Sbjct: 60 FCAGFYLREIPLDKGVAGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGIS 119 Query: 154 ISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAK 213 ++ I K V + +G + L ++VG+ A+++MLT R++ + AK Sbjct: 120 LASDMAICADSAKFVCAWHTIGIGN--DTATSYSLARIVGMRRAMELMLTDRTLYPEEAK 177 Query: 214 KMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKIS 257 GLV ++ + EVA A+ LA Sbjct: 178 DWGLVSRVYPK-------------DEFREVAWKVARELAAAPTH 208 >3OME-A nrPDB Length = 282 Score = 167 bits (422), Expect = 2e-41, Method: Composition-based stats. Identities = 49/214 (22%), Positives = 98/214 (45%), Gaps = 19/214 (8%) Query: 37 TRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG 96 + +I+YGV +A + +N P + N + EL E ++++ +++ + Sbjct: 21 SMVYIDYGVADSIATITLNRPEA-ANAQNPELLDELDAAWTRAAEDNEVK-VIILRANGK 78 Query: 97 CFIAGADIN---MLAACKTLQEVTQL-SQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEV 152 F AG D+ + +L+ + Q ++ + KP +AA+ G C+ GGL + Sbjct: 79 HFSAGHDLRGGGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLL 138 Query: 153 AISCQYRIATKDRKTVLGTPEVLLGA--LPGAGGTQRLPKMVGVPAALDMMLTGRSIRAD 210 C +A+ D + P L+G + G T L G A +++ TGR++ A+ Sbjct: 139 CWPCDLILASDDA--LFSDPVALMGIGGVEYHGHTWEL----GPRKAKEILFTGRALTAE 192 Query: 211 RAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVA 244 A++ G+V+++V + +T E E++A Sbjct: 193 EAERTGMVNRVV-----ARDELDAQTRELAEQIA 221 >3HIN-A nrPDB Length = 275 Score = 167 bits (422), Expect = 2e-41, Method: Composition-based stats. Identities = 61/193 (31%), Positives = 92/193 (47%), Gaps = 7/193 (3%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + G V + +N P K N L+ L + + + +I DQIR AV+I F A Sbjct: 18 LVVDTVGPVLTIGLNRPK-KRNALNDGLMAALKDCLTDIP--DQIR-AVVIHGIGDHFSA 73 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 G D++ L + + SQ R+ +K++ P++AA+ G+ +GGGLE+A + R+ Sbjct: 74 GLDLSELRERDATEGLV-HSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHIRV 132 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 A + PE G G GG+ RLP+++GV DMMLTGR A G Sbjct: 133 A--EASAYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQY 190 Query: 221 LVEPLGPGLKPPE 233 L+E K E Sbjct: 191 LIENGSAYDKALE 203 >3BPT-A nrPDB Length = 363 Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats. Identities = 49/233 (21%), Positives = 92/233 (39%), Gaps = 8/233 (3%) Query: 40 HINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFI 99 + G KG V+ +N P +N L+ + + + + + ++ + F Sbjct: 7 EVLLGKKGCTGVITLNRPKF-LNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFC 65 Query: 100 AGADINMLAACKTLQE--VTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQ 157 AG DI +++ + ++ +E + + KP VA I+G +GGG+ +++ Q Sbjct: 66 AGGDIRVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQ 125 Query: 158 YRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGL 217 +R+A K + PE +G P GG LP++ G + LTG ++ + G+ Sbjct: 126 FRVA--TEKCLFAMPETAIGLFPDVGGGYFLPRLQG-KLGYFLALTGFRLKGRDVYRAGI 182 Query: 218 VDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTA 270 V+ L EE + A L + K D+ L Sbjct: 183 ATHFVDS--EKLAMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEE 233 >2VSU-C nrPDB Length = 275 Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats. Identities = 55/224 (24%), Positives = 97/224 (43%), Gaps = 21/224 (9%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + ++ +A V +N P K N +S L+ E +V+ + D ++++ + A Sbjct: 11 VKVEIEDGIAFVILNRPE-KRNAMSPTLNREMIDVLETLE-QDPAAGVLVLTGAGEAWTA 68 Query: 101 GADINM-LAACKTLQEVTQ--LSQEAQRIVEKLEK-STKPIVAAINGSCLGGGLEVAISC 156 G D+ E+ Q + +EA + KL + KP +A +NG C GGG ++C Sbjct: 69 GMDLKEYFREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLVAC 128 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 I + G E+ G PG ++ + VG +L ++TG++ +A +MG Sbjct: 129 DLAICADEA--TFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMG 186 Query: 217 LVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKR 260 LV++ V + L EV I A+ L +K R Sbjct: 187 LVNESVP-------------LAQLREVTIELARNLLEKNPVVLR 217 >2A81-A nrPDB Length = 250 Score = 164 bits (416), Expect = 1e-40, Method: Composition-based stats. Identities = 41/191 (21%), Positives = 79/191 (41%), Gaps = 4/191 (2%) Query: 47 GDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINM 106 +V V+ ++ PN K N S+ L + + + A D +R+ V+ F AG D N Sbjct: 8 DEVRVITLDHPN-KHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFNE 66 Query: 107 LAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRK 166 + +++ + + + + KP +AA++G +G G + A+ R+ Sbjct: 67 VKQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMASTAN 126 Query: 167 TVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLG 226 V+ PE+ G + G L G +++ +S+ A R LV+Q+VE Sbjct: 127 FVM--PELKHGI-GCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESSA 183 Query: 227 PGLKPPEERTI 237 + + Sbjct: 184 LLDAAITQAHV 194 >5VE2-A nrPDB Length = 275 Score = 164 bits (414), Expect = 2e-40, Method: Composition-based stats. Identities = 63/262 (24%), Positives = 106/262 (40%), Gaps = 13/262 (4%) Query: 39 THINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCF 98 +N + V + IN P K N L++EL++ ++ + DQIR AVL+++ F Sbjct: 25 KSLNVSLNNRVLSLTINRPELK-NALNRELYAALADELERSNHDDQIR-AVLLTANGDTF 82 Query: 99 IAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQY 158 AG D++ R ++ + + PIV A+NG +G GL + + C Sbjct: 83 TAGNDLDDFINPVEESGTPS----VIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDM 138 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV 218 A+K + P +G +P A + LP VG A D+ML GR + A A GLV Sbjct: 139 VYASKSAR--FRAPFTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLV 196 Query: 219 DQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFV 278 ++ E +++ E+VA + K + + + F Sbjct: 197 TRVFEDDV-----LVAESLKIAEQVASLAPNSVKQSKRLIRGVNKEEVQAQMKREGVIFA 251 Query: 279 RQQVYKKVEEKVRKQTKGLYPA 300 Q + +E V + P Sbjct: 252 EQLASAEFKESVAAFFEKRAPH 273 >5MRE-88 nrPDB Length = 457 Score = 163 bits (412), Expect = 3e-40, Method: Composition-based stats. Identities = 53/191 (27%), Positives = 88/191 (46%), Gaps = 12/191 (6%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSK-PGCFI 99 + + V+ V+ +N P K+N L+ E+ + +NE SD +L SS P F Sbjct: 4 VLFTVQDTARVITLNRPK-KLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFC 62 Query: 100 AGADINM---LAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 AG D+ K + + + + ++ KPIV ++G +GGG+ ++I Sbjct: 63 AGGDVATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHT 122 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVP-----AALDMMLTGRSIRADR 211 +RIAT++ K PE+ +G P G T LP++V + AL + LTG + Sbjct: 123 PFRIATENTKW--AMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGAD 180 Query: 212 AKKMGLVDQLV 222 A +GL V Sbjct: 181 AYMLGLASHYV 191 >1XX4-A nrPDB Length = 261 Score = 161 bits (407), Expect = 1e-39, Method: Composition-based stats. Identities = 53/228 (23%), Positives = 97/228 (42%), Gaps = 8/228 (3%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + + +AV++ +P VN+LS E +EF + ++ IR +L S +PG F A Sbjct: 8 VEKEGEAGIAVMKFKNP--PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIFSA 65 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 G D+ + + + + Q + +L S +++AING+ GG +A++C YRI Sbjct: 66 GLDLMEM-YGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYRI 124 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 + K +G E LLG + +G AA + G A K+GLVD+ Sbjct: 125 MADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVDE 184 Query: 221 LVEPLGPGLKPPEERTI-----EYLEEVAITFAKGLADKKISPKRDKG 263 +V K ++ ++ + + + +R+ Sbjct: 185 VVPEDQVHSKARSVMAKWFTIPDHSRQLTKSMMRKATADNLIKQREAD 232 >3T8B-A nrPDB Length = 334 Score = 159 bits (401), Expect = 5e-39, Method: Composition-based stats. Identities = 51/285 (17%), Positives = 103/285 (36%), Gaps = 28/285 (9%) Query: 39 THINYGVKGDVAVVR--INSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG 96 T I Y D A VR N P + N E V++ S + +L + P Sbjct: 55 TDITYHRHVDDATVRVAFNRPEVR-NAFRPHTVDELYRVLDHARMSPDVGVVLLTGNGPS 113 Query: 97 ------CFIAGADINMLA----------ACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAA 140 F +G D + T+ + + K ++ Sbjct: 114 PKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHILEVQRLIRFMPKVVICL 173 Query: 141 INGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDM 200 +NG GGG + + C +A+++ + +G+ G G+ L + VG A ++ Sbjct: 174 VNGWAAGGGHSLHVVCDLTLASREY-ARFKQTDADVGSFDGGYGSAYLARQVGQKFAREI 232 Query: 201 MLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITF--AKGLADKKISP 258 GR+ A++ +MG V+ + E E +++ E+ A+ + + Sbjct: 233 FFLGRTYTAEQMHQMGAVNAVAEH-----AELETVGLQWAAEINAKSPQAQRMLKFAFNL 287 Query: 259 KRDKGLVEKLTAYAMT-IPFVRQQVYKKVEEKVRKQTKGLYPAPL 302 D + ++L A T + ++ + + + ++K+ P P Sbjct: 288 LDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWSPFPR 332 >4J2U-A nrPDB Length = 365 Score = 159 bits (401), Expect = 6e-39, Method: Composition-based stats. Identities = 51/298 (17%), Positives = 103/298 (34%), Gaps = 19/298 (6%) Query: 31 GSSALL--TRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSA 88 G+ L + + + + ++ P + +N L+ + E + ++ Sbjct: 14 GTENLYFQSMSDVLIRKVRRAGRITLSRPAA-LNALTCAMVQEIDAALRGWIGDPEVELV 72 Query: 89 VLISSKPGCFIAGADINMLAACKTLQEVT---QLSQEAQRIVEKLEKSTKPIVAAINGSC 145 V+ + P F AG DI L + + R+ +++ KPIV+ + G Sbjct: 73 VIDAEGPRAFCAGGDIAELHGRGVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFT 132 Query: 146 LGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGR 205 +GGG+ + ++RI + + + PE +G +P GGT L + G + + LTG Sbjct: 133 MGGGVGLGCHARHRIVGETSQ--ISMPECAIGLVPDVGGTHLLARAPG-RIGVWLGLTGA 189 Query: 206 SIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISP-KRDKGL 264 + A G D+ V + + A + P +D+ Sbjct: 190 RMGPGDAIFAGFADRFVPEADWPDLIAALEGGD------LALPDHAAPEGRLPVLQDEID 243 Query: 265 VEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLC 322 A + E ++ + +PL + ++ G AG Sbjct: 244 RLFAGTLAEIPARLEATDTPLAAEALKALRRS---SPLALAATLEILQRLGPSAGIRE 298 >4IZC-A nrPDB Length = 275 Score = 157 bits (397), Expect = 2e-38, Method: Composition-based stats. Identities = 52/204 (25%), Positives = 85/204 (41%), Gaps = 12/204 (5%) Query: 46 KGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADIN 105 V VV +N P+ K N L E + AV+++ F AG D+ Sbjct: 18 DNGVCVVTLNRPD-KRNALDVATIEELVTFFSTAHRK--GVRAVVLTGAGDHFCAGLDLV 74 Query: 106 M-LAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKD 164 A ++ + + K+E PI+AA+ G+ +GGGL +A + R+ D Sbjct: 75 EHWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRVM--D 132 Query: 165 RKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEP 224 + T PE G G G T R+ M+G +DM+LTGR + A +GL + E Sbjct: 133 QSTYFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEG 192 Query: 225 LGPGLKPPEERTIEYLEEVAITFA 248 ++ +E +++A Sbjct: 193 SSF------DKAMELADKIASNLP 210 >3JU1-A nrPDB Length = 407 Score = 156 bits (393), Expect = 5e-38, Method: Composition-based stats. Identities = 56/233 (24%), Positives = 94/233 (40%), Gaps = 16/233 (6%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINML- 107 V VV +N + +N L ++ + +N I VL S F AG D+ L Sbjct: 52 VGVVTLNVEKA-LNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALY 110 Query: 108 -----AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIAT 162 A + + +E R+ L KP++ +G +GGGL + +++ T Sbjct: 111 HASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVLVWGDGIVMGGGLGLMAGASHKVVT 170 Query: 163 KDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 + + + PEV +G P GG+ L +M G L + LT + A A +GL D + Sbjct: 171 ETSR--IAMPEVTIGLYPDVGGSYFLNRMPG-KMGLFLGLTAYHMNAADACYVGLADHYL 227 Query: 223 EPLGPGLKPPEERTIEYLEEVAI------TFAKGLADKKISPKRDKGLVEKLT 269 L T+++ + A+ T L+++ PK D L E Sbjct: 228 NRDDKELMFDAMATLDWSDSPALNHQRLDTMINELSNQVDIPKGDSVLAESQE 280 >4FZW-C nrPDB Length = 274 Score = 150 bits (379), Expect = 2e-36, Method: Composition-based stats. Identities = 58/220 (26%), Positives = 102/220 (46%), Gaps = 22/220 (10%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 I V+ V + +N P ++N+ + E+H++ +E + ++ D IR +L++ F A Sbjct: 17 ILSHVEKGVMTLTLNRPE-RLNSFNDEMHAQLAECLKQVERDDTIRC-LLLTGAGRGFCA 74 Query: 101 GADINMLAACKTLQEVTQLSQEAQR----IVEKLEKSTKPIVAAINGSCLGGGLEVAISC 156 G D+N L +R +V +L K KP++ A+NG G G +A+ Sbjct: 75 GQDLNDRN-VDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGG 133 Query: 157 QYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMG 216 IA + K V+ LG +P GGT LP++ G A+ + L G + A++A + G Sbjct: 134 DIVIAARSAKFVMAFS--KLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWG 191 Query: 217 LVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKI 256 ++ Q+V+ E L + A A+ LA + Sbjct: 192 MIWQVVD-------------DETLADTAQQLARHLATQPT 218 >3HE2-A nrPDB Length = 264 Score = 148 bits (373), Expect = 9e-36, Method: Composition-based stats. Identities = 47/233 (20%), Positives = 88/233 (37%), Gaps = 20/233 (8%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 I V + + P + N L+ +L E ++ + + D A++++ + F A Sbjct: 23 IGITQAEAVLTIELQRPE-RRNALNSQLVEELTQAIRKA--GDGSARAIVLTGQGTAFCA 79 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 GAD++ A + + ++ S P+V AING +G GL++A+ C R+ Sbjct: 80 GADLSGDA------FAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRV 133 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 D P G +RL +VG A M+L+ + A+ A G+ ++ Sbjct: 134 VAPDA--FFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANR 191 Query: 221 LVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAM 273 + + E+A + K D + E A+ Sbjct: 192 I---------GTLADAQAWAAEIARLAPLAIQHAKRVLNDDGAIEEAWPAHKE 235 >4JSB-A nrPDB Length = 296 Score = 146 bits (368), Expect = 3e-35, Method: Composition-based stats. Identities = 49/198 (24%), Positives = 95/198 (47%), Gaps = 22/198 (11%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + + G+VA + ++ P+ + N ++ + +E + + + + Q V+I+ + F + Sbjct: 38 LTLTIDGEVARITLSRPH-RRNAMTGRMWTELARIGHTL---PQAVRIVVITGEGPTFSS 93 Query: 101 GADINMLAACKTLQEVTQLSQ----------------EAQRIVEKLEKSTKPIVAAINGS 144 G D++M A K E T + Q L ++ +AA+ G Sbjct: 94 GIDLDMFQAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIAAVRGH 153 Query: 145 CLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTG 204 +G G ++A+SC RI + + + P LG +P GTQ L ++VGV A+++ LT Sbjct: 154 AIGAGFQLALSCDIRILSDTAQLCMKEP--ALGLVPDLTGTQPLVELVGVNRAIELCLTA 211 Query: 205 RSIRADRAKKMGLVDQLV 222 R+I A A ++ L +++V Sbjct: 212 RTIDAAEAAQLRLAERVV 229 >3LAO-A nrPDB Length = 258 Score = 145 bits (365), Expect = 8e-35, Method: Composition-based stats. Identities = 57/244 (23%), Positives = 100/244 (40%), Gaps = 11/244 (4%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 + +G + ++ ++ K N + ++ + M E S++ R AVL + F A Sbjct: 14 VTREQRGHLFLIGLDRA-GKRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGE-HFTA 71 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 G D+ LA + +KP+V A+ G+C G+E+ ++ + Sbjct: 72 GLDLMELAPKLAASGFRYPDGGVDPWGVVQPRRSKPLVVAVQGTCWTAGIELMLNADIAV 131 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 A + + EVL G P G T R P+ G A+ +LTG AD A +M L+ + Sbjct: 132 AARGTR--FAHLEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTE 189 Query: 221 LVEPLGPGLKPPEERTIEYLEEVAITFAKGL--ADKKISPKRDKGLVEKLTAYAMTIPFV 278 +VEP R +EY E +A + A + RD+G L+ ++ + Sbjct: 190 VVEPGEELA-----RALEYAERIARAAPLAVRAALQSAFQGRDEGDDAALSRVNESLAAL 244 Query: 279 RQQV 282 Sbjct: 245 IGSE 248 >4HDT-A nrPDB Length = 353 Score = 144 bits (363), Expect = 1e-34, Method: Composition-based stats. Identities = 56/234 (23%), Positives = 95/234 (40%), Gaps = 10/234 (4%) Query: 31 GSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVL 90 GS + V+G V ++ +N P + +N+L+ + + +E + D +R+ +L Sbjct: 1 GSMVTAKNEDVLVNVEGGVGLLTLNRPKA-INSLTHGMVTTMAERLAAWENDDSVRAVLL 59 Query: 91 ISSKPGCFIAGADINML--AACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGG 148 + AG D+ + +A E + + R+ + + KP V+ ++G +GG Sbjct: 60 TGAGERGLCAGGDVVAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGG 119 Query: 149 GLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIR 208 G+ V R+ T K + PEV +G +P GGT L + G L LTG Sbjct: 120 GVGVGAHGNVRVVTDTTK--MAMPEVGIGFIPDVGGTYLLSRAPG-KLGLHAALTGAPFS 176 Query: 209 ADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDK 262 A MG D V P K E + V A + SP ++ Sbjct: 177 GADAIVMGFADHYV----PHDKIDEFTRAVIADGVDAALAAHAQEPPASPLAEQ 226 >4JFC-A nrPDB Length = 281 Score = 141 bits (354), Expect = 2e-33, Method: Composition-based stats. Identities = 47/232 (20%), Positives = 104/232 (44%), Gaps = 15/232 (6%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 I +G ++ +++P + N L E+++ E +N + +IRS V+I+ + F A Sbjct: 27 IKSTSEGQTLILTLSNPEFR-NALGPEIYAAGIEALNAAENNPEIRS-VVITGEGAVFCA 84 Query: 101 GADINMLAACK--TLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQY 158 G ++ L A + + Q + ++ + KP++AA+ G+ G G +A++C + Sbjct: 85 GGNLQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDF 144 Query: 159 RIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLV 218 +A + V+ V G P GG+ L + + A ++++ G I A R +GLV Sbjct: 145 VVAASNAVFVMSYSTV--GLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLV 202 Query: 219 DQLVEPLGPGLKPPEER---------TIEYLEEVAITFAKGLADKKISPKRD 261 +++ + + ++E+ + ++++ +RD Sbjct: 203 NKVASAGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERD 254 >5KJP-A nrPDB Length = 265 Score = 139 bits (351), Expect = 3e-33, Method: Composition-based stats. Identities = 61/264 (23%), Positives = 114/264 (43%), Gaps = 11/264 (4%) Query: 30 TGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAV 89 + S A T + + + ++ IN P +K N ++ + ++ M+++ + A+ Sbjct: 6 SESDAANTEPEVLVEQRDRILIITINRPKAK-NAVNAAVSRGLADAMDQLDGDAGLSVAI 64 Query: 90 LISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGG 149 L + G F AG D+ A + + E + + TKP++AA+ G L GG Sbjct: 65 L-TGGGGSFCAGMDLKAFARGENV------VVEGRGLGFTERPPTKPLIAAVEGYALAGG 117 Query: 150 LEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRA 209 E+A++ +A +D + G PEV G + G GG RLP+ + A+++ LTG ++ A Sbjct: 118 TELALAADLIVAARD--SAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPA 175 Query: 210 DRAKKMGLVDQLVEPLGPGLKPPE-ERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKL 268 +RA ++GLV+ L EP I +A+ K + + D E++ Sbjct: 176 ERAHELGLVNVLAEPGTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQM 235 Query: 269 TAYAMTIPFVRQQVYKKVEEKVRK 292 + + R+ Sbjct: 236 KILVPVFTSNDAKEGAIAFAERRR 259 >4ZU2-A nrPDB Length = 272 Score = 137 bits (346), Expect = 1e-32, Method: Composition-based stats. Identities = 60/250 (24%), Positives = 100/250 (40%), Gaps = 11/250 (4%) Query: 48 DVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINML 107 V + +N P S+ N +S + E V+ + +R A+++ G F AG DI + Sbjct: 16 GVLRITLNRPQSR-NAMSLAMVGELRAVLAAVRDDRSVR-ALVLRGADGHFCAGGDIKDM 73 Query: 108 AACKTLQE--VTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDR 165 A + L++ ++E+ + + + +VA + G+ LGGG +A IA D Sbjct: 74 AGARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDVAIAAADA 133 Query: 166 KTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLVEPL 225 + G PE LG LP A + + +G+ A + LT A ++GLV E Sbjct: 134 Q--FGLPETSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLV-HFCEAD 189 Query: 226 GPGLKPPEERTIEYLEEV---AITFAKGLADKKISPKRDKGLVEKLTAYAMTIPFVRQQV 282 L+ E T+E L A K L S + L + +A + Sbjct: 190 ADALEQRLEETLEQLRRCAPNANAATKALLLASESGELGALLDDAARQFAEAVGGAEGSE 249 Query: 283 YKKVEEKVRK 292 + RK Sbjct: 250 GTLAFVQKRK 259 >4Q1J-A nrPDB Length = 268 Score = 129 bits (325), Expect = 4e-30, Method: Composition-based stats. Identities = 60/270 (22%), Positives = 107/270 (39%), Gaps = 48/270 (17%) Query: 49 VAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPG---CFIAGADIN 105 V ++ I S +V + + FS+ + D I++ I P + G D N Sbjct: 25 VELIEIESAIIQVKMQDRTHKNAFSQELT----DDLIQAFEYIRQNPKYKAVILTGYD-N 79 Query: 106 MLAACKTLQEVTQLSQEAQRIVEKLEK-----STKPIVAAINGSCLGGGLEVAISCQYRI 160 A+ T + + ++ Q + + P++AA+ G +GGG + + I Sbjct: 80 YFASGGTQEGLLRIQQGLTKFTDDNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVI 139 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 +++ +V + G PG G T +PK +G A +++L S R +K G+ Sbjct: 140 LSRE--SVYTANFMKYGFTPGMGATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGV--- 194 Query: 221 LVEPLGPGLKPPEERTIEYLEEVAITFAK-------GLADKKISPKRDKGLVEKLTAYAM 273 P P ++Y E+A A+ L D ++P RD+ Sbjct: 195 ------PFKVLPRAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQ----------- 237 Query: 274 TIPFVRQQVYKKVE-----EKVRKQTKGLY 298 +P V +Q E E+V+ + KGLY Sbjct: 238 -LPRVIEQELMMAEKTFHHEEVKSRIKGLY 266 >3I47-A nrPDB Length = 268 Score = 129 bits (324), Expect = 5e-30, Method: Composition-based stats. Identities = 47/222 (21%), Positives = 96/222 (43%), Gaps = 12/222 (5%) Query: 36 LTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKP 95 ++ + + Y ++ V ++ +N SK N +L +E ++ +R +++ + Sbjct: 1 MSLSDLLYEIQDKVGLLTMNR-ISKHNAFDNQLLTEMRIRLDSAINDTNVR-VIVLKANG 58 Query: 96 GCFIAGADINMLAACKTLQEVTQLSQEA--QRIVEKLEKSTKPIVAAINGSCLGGGLEVA 153 F AGAD+ + + E L ++ + +S KP +A + G+ GGG +A Sbjct: 59 KHFSAGADLTWMQSMANFTEEENLEDSLVLGNLMYSISQSPKPTIAMVQGAAFGGGAGLA 118 Query: 154 ISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAK 213 +C IA+ + EV LG +P A + + + +G AA + ++ A RA Sbjct: 119 AACDIAIASTSARFCFS--EVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAY 175 Query: 214 KMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKK 255 + LV V E T++Y +++ + + + K Sbjct: 176 SLNLVQHCVP-----DDTLLEFTLKYASQISNNAPEAVKNSK 212 >3M6N-A nrPDB Length = 305 Score = 123 bits (308), Expect = 3e-28, Method: Composition-based stats. Identities = 50/215 (23%), Positives = 83/215 (38%), Gaps = 21/215 (9%) Query: 89 VLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKS------TKPIVAAIN 142 V+++S F G D+ + + +L AQR V + +A + Sbjct: 89 VVLASDSDVFNLGGDLALFCQLIREGDRARLLDYAQRCVRGVHAFHVGLGARAHSIALVQ 148 Query: 143 GSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMML 202 G+ LGGG E A+SC IA + ++G PEVL PG G + + + A +ML Sbjct: 149 GNALGGGFEAALSCHTIIA--EEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQKIML 206 Query: 203 TGRSIRADRAKKMGLVDQLVEPLGPGLKPPEE------------RTIEYLEEVAITFAKG 250 G A++ MGLVD++V P G G+ E+ ++ + E+ Sbjct: 207 EGNLYSAEQLLGMGLVDRVV-PRGQGVAAVEQVIRESKRTPHAWAAMQQVREMTTAVPLE 265 Query: 251 LADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKK 285 + D + + VR Q + Sbjct: 266 EMMRITEIWVDTAMQLGEKSLRTMDRLVRAQSRRS 300 >2NP9-A nrPDB Length = 440 Score = 118 bits (295), Expect = 1e-26, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 78/220 (35%), Gaps = 27/220 (12%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISS------- 93 ++ + VA + + + ++N + + ++ +R +L Sbjct: 169 VHLERRDGVARLTMCR-DDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRY 227 Query: 94 -KPGCFIAGADINMLAACKTLQEVTQLSQEAQRI---------------VEKLEKSTKPI 137 F AG ++ L+ + +E I + KP Sbjct: 228 RGKRVFSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPW 287 Query: 138 VAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAA 197 VAA++G +GGG ++ + +A+ D P G +PGA RL + G + Sbjct: 288 VAAVDGFAIGGGAQLLLVFDRVLASSDA--YFSLPAAKEGIIPGAANL-RLGRFAGPRVS 344 Query: 198 LDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTI 237 ++L GR I A + LVD++VEP T Sbjct: 345 RQVILEGRRIWAKEPEARLLVDEVVEPDELDAAIERSLTR 384 >3HP0-A nrPDB Length = 267 Score = 107 bits (268), Expect = 2e-23, Method: Composition-based stats. Identities = 42/190 (22%), Positives = 72/190 (37%), Gaps = 7/190 (3%) Query: 33 SALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLIS 92 +L+T I + V + + P + NT++ L E +V+N+ S + V++ Sbjct: 1 MSLVTYQTIKVRFQASVCYITFHRPEAN-NTINDTLIEECLQVLNQCETS--TVTVVVLE 57 Query: 93 SKPGCFIAGADINM-LAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLE 151 P F GAD K ++ + + KL+ ++ + G GGL Sbjct: 58 GLPEVFCFGADFQEIYQEMKRGRKQASSQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLG 117 Query: 152 VAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADR 211 + IA D+ E+L G P L + +G A M L + I Sbjct: 118 FVSATDIAIA--DQTASFSLSELLFGLYPACV-LPFLIRRIGRQKAHYMTLMTKPISVQE 174 Query: 212 AKKMGLVDQL 221 A + GL+D Sbjct: 175 ASEWGLIDAF 184 >4HC8-A nrPDB Length = 255 Score = 101 bits (252), Expect = 1e-21, Method: Composition-based stats. Identities = 41/237 (17%), Positives = 85/237 (35%), Gaps = 12/237 (5%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 ++Y K +AV+ ++ + KVN L + + ++ D A++I+ F Sbjct: 7 VSYTRKDSIAVISMD--DGKVNALGPAMQQALNAAIDNADRDD--VGALVITGNGRVFSG 62 Query: 101 GADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRI 160 G D+ +L + + +Q + + + +L KP+V A G + G + +R+ Sbjct: 63 GFDLKILTSGE-VQPAIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRV 121 Query: 161 ATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQ 220 A + EV +G + + + A ++ + A G +D+ Sbjct: 122 AA--HAYNIQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDE 179 Query: 221 LVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPF 277 + P + R E E A A K+ + D + + F Sbjct: 180 IALP-----EVVVSRAEEAAREFAGLNQHAHAATKLRSRADALTAIRAGIDGIAAEF 231 >4ZDC-A nrPDB Length = 300 Score = 79.4 bits (194), Expect = 6e-15, Method: Composition-based stats. Identities = 37/212 (17%), Positives = 80/212 (37%), Gaps = 13/212 (6%) Query: 41 INYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIA 100 I+Y ++G ++ + +P++ +N L E + E++ + + ++ SS F + Sbjct: 31 ISYRIEGPFFIIHLINPDN-LNALEGEDYIYLGELLELADRNRDVYFTIIQSSG-RFFSS 88 Query: 101 GADINMLAACKTLQE----------VTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGL 150 GAD +A + V+ + + K +K ++ +NG +G Sbjct: 89 GADFKGIAKAQGDDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSA 148 Query: 151 EVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRAD 210 + C + + K L P LG + G T LP G + ++ + + D Sbjct: 149 ALVALCDIVY-SINDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYD 207 Query: 211 RAKKMGLVDQLVEPLGPGLKPPEERTIEYLEE 242 + G + + + + +E L E Sbjct: 208 IMCENGFISKNFNMPSSNAEAFNAKVLEELRE 239 >3CTV-A nrPDB Length = 110 Score = 71.3 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 28/93 (30%), Positives = 45/93 (48%), Gaps = 7/93 (7%) Query: 663 PKSEVSSDEDIQFRL--VTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRF 720 P+ + S D + +NEAV ++ G+ ATP + D GL P GPF Sbjct: 7 PQIDSSKATDKINPMDFTFVEINEAVKLVEMGV-ATPQDIDTAIKLGLNRP---FGPFEL 62 Query: 721 VDLYGAQKIVDRLKKYEAAYGKQ-FTPCQLLAD 752 +GA++I RL++ +GK+ F P + L + Sbjct: 63 AKQFGAEQIAKRLEELAKQFGKKIFEPAKTLKE 95 Score = 43.2 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 36/82 (43%), Gaps = 3/82 (3%) Query: 555 MSEVIRILQEGVD-PKKLD-SLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFG 612 ++E +++++ GV P+ +D ++ P G L + G + E+L K FG++ Sbjct: 28 INEAVKLVEMGVATPQDIDTAIKLGLNRPFGPFELAKQFGAEQIAKRLEELAKQFGKKIF 87 Query: 613 GGNPELLT-QMVSKGFLGRKSG 633 L ++ G+ G Sbjct: 88 EPAKTLKEGKLEELLKAGKAEG 109 >2BC1-A nrPDB Length = 490 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 38/96 (39%), Gaps = 6/96 (6%) Query: 359 KDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALT 418 KD+K +A++GAG +G +A+ KG + +L D T L + L K ++ Sbjct: 192 KDIKRVAVVGAGYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGI 251 Query: 419 SFERDSIFSNLTGQLDYQGF------EKADMVIEAV 448 + G + DMVI AV Sbjct: 252 QLAFGETVKEVAGNGKVEKIITDKNEYDVDMVILAV 287 >6AON-A nrPDB Length = 478 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 34/89 (38%), Gaps = 1/89 (1%) Query: 330 LVMTKESKALMGLYHGQVLCKKNKFGAPQKDV-KHLAILGAGLMGAGIAQVSVDKGLKTI 388 + ++ L GL + N V K L ++GAG++G + V G + Sbjct: 154 VATGSSARELPGLPFDEKNILSNDGALNIGAVPKKLGVIGAGVIGLEMGSVWRRLGAEVT 213 Query: 389 LKDATLTALDRGQQQVFKGLNDKVKKKAL 417 + +A L QQV K K+ L Sbjct: 214 ILEAMPEFLAAADQQVAKEALKSFAKQGL 242 >4R16-A nrPDB Length = 418 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 12/86 (13%), Positives = 31/86 (36%), Gaps = 4/86 (4%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 +A+LG G +G A + G + D + +++ G+ ++ + + Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYDVVGYDIRSEVI----KKINSGVAHIIEPEIDRRLKE 57 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAV 448 L + + +++ I V Sbjct: 58 VLSLGKLKVTDRVEDLKGSNVFIICV 83 >2EQ6-A nrPDB Length = 464 Score = 42.0 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 41/243 (16%), Positives = 76/243 (31%), Gaps = 33/243 (13%) Query: 193 GVPAALDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEY---LEEVAITFAK 249 G AA+ G + A A ++G V V + T+ + E + Sbjct: 18 GYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAETLHHLKVAEGFGLKAKP 77 Query: 250 GLADKKISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVK 309 L KK+ RD+ + + + ++ + V P ++ Sbjct: 78 ELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFARLV---------GPKEV----- 123 Query: 310 TGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVL-----CKKNKFGAPQKDVKHL 364 + G K L E L G G+ + K + G P K L Sbjct: 124 -------EVGGERYGAKSLILATGSEPLELKGFPFGEDVWDSTRALKVEEGLP----KRL 172 Query: 365 AILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDS 424 ++G G +G + QV G + L + L +G + L ++K+ + + Sbjct: 173 LVIGGGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRTKTK 232 Query: 425 IFS 427 Sbjct: 233 AVG 235 >3X2F-A nrPDB Length = 411 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 24/154 (15%), Positives = 58/154 (37%), Gaps = 13/154 (8%) Query: 318 AGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDV------KHLAILGAGL 371 + ++ +SK + L+ + ++ + A ++ K++ + G G Sbjct: 149 KALEETGKLRVPVIAVNDSK-MKYLFDNRYGTGQSTWDAIMRNTNLLVAGKNVVVAGYGW 207 Query: 372 MGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTG 431 G GIA + G + I+ + + + + G K+A+ + S T Sbjct: 208 CGRGIALRAAGLGARVIVTEVDP---VKAVEAIMDGFTVMPMKEAVKIADFVITASGNTD 264 Query: 432 QLDYQG---FEKADMVIEAVFEDLSLKHRVLKEV 462 L + + ++ A ++ + RVL+E+ Sbjct: 265 VLSKEDILSLKDGAVLANAGHFNVEIPVRVLEEI 298 >1F8S-A nrPDB Length = 498 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 24/62 (38%) Query: 334 KESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDAT 393 ++ + + L + KH+ I+GAG+ G A V G + + +A+ Sbjct: 6 PLAECFQENDYEEFLEIARNGLKATSNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEAS 65 Query: 394 LT 395 Sbjct: 66 ER 67 >2GF2-A nrPDB Length = 296 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 44/113 (38%), Gaps = 15/113 (13%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERD 423 + +G G MG +A+ + G I+ D A ++ V A + + D Sbjct: 3 VGFIGLGNMGNPMAKNLMKHGYPLIIYDVFPDAC----KEFQDAGEQVVSSPADVAEKAD 58 Query: 424 SIFSNLTGQLDY-----------QGFEKADMVIEAVFEDLSLKHRVLKEVEAV 465 I + L ++ + +K ++I++ D ++ + KEVE + Sbjct: 59 RIITMLPTSINAIEAYSGANGILKKVKKGSLLIDSSTIDPAVSKELAKEVEKM 111 >3KVE-A nrPDB Length = 486 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 24/63 (38%) Query: 334 KESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDAT 393 + + + L + KH+ ++GAG+ G A V G K + +A+ Sbjct: 6 PLEECFRETDYEEFLEIARNGLKKTSNPKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEAS 65 Query: 394 LTA 396 A Sbjct: 66 ERA 68 >4D3F-A nrPDB Length = 310 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 40/109 (36%), Gaps = 12/109 (11%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K + ++G G MG +A V ++ G + + + Q V KG + Sbjct: 22 KSVTVIGLGPMGQAMADVFLEYGYSVTVWN---RTSSKADQLVAKGAIRVSTVNEALAAN 78 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHC 470 I S DY ++E V E+L K VL + + P+ Sbjct: 79 ELVILSL----TDYNVMYS---ILEPVSENLFGK--VLVNLSSDTPEKA 118 >3OJO-A nrPDB Length = 431 Score = 40.1 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 18/100 (18%), Positives = 37/100 (37%), Gaps = 14/100 (14%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR-----------GQQQVFKGLND 410 L ++G G +G + + G+ + D +D+ G Q+V++ + Sbjct: 12 SKLTVVGLGYIGLPTSIMFAKHGVDVLGVDINQQTIDKLQNGQISIEEPGLQEVYEEVLS 71 Query: 411 KVKKKALTSFERDSIFSNLTGQLDYQG-FEKAD--MVIEA 447 K K T+ E +F + + D +V+ A Sbjct: 72 SGKLKVSTTPEASDVFIIAVPTPNNDDQYRSCDISLVMRA 111 >4WJI-A nrPDB Length = 293 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 31/196 (15%), Positives = 62/196 (31%), Gaps = 47/196 (23%) Query: 358 QKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL 417 + + +A++G GL+G+ IA +D L + + L Sbjct: 1 AQQFQTIALIGIGLIGSSIA------------RDIREKQLAGTIVVTTRSEATLKRAGEL 48 Query: 418 TSFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS--N 475 +R ++ + + E AD+V+ +V + V E+ A + I + Sbjct: 49 GLGDRYTLSA-------AEAVEGADLVVVSVP--VGASGAVAAEIAAHLKPGAIVTDVGS 99 Query: 476 TSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLE------------------IITTEKT 517 T I+++A P+ V H+ P + E + T Sbjct: 100 TKGSVIAQMAPHL--PKDV---HFV-PGHPIAGTEHSGPDAGFAGLFRGRWCILTPPAGT 153 Query: 518 SKDTSASAVAVGLKQG 533 ++ A G Sbjct: 154 DEEAVARLRLFWETLG 169 >4XRR-A nrPDB Length = 456 Score = 39.7 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 29/86 (33%), Gaps = 4/86 (4%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 + I GAG +G +A +G + + D+ + G + + Sbjct: 17 KVVIAGAGYVGTCLAVTLAGRGAEVVAVDSDP----GTVADLRAGRCRLPEPGLAGAVRD 72 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAV 448 + LT Y AD+VI V Sbjct: 73 LAATGRLTASTSYDPVGAADVVIVTV 98 >5DT9-A nrPDB Length = 387 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 29/151 (19%), Positives = 55/151 (36%), Gaps = 12/151 (7%) Query: 302 LKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDV 361 LK + G++ D L E F + ++ + G D Sbjct: 66 LKFVGTATAGMDH-VDQALLRERGIFFTAAPGCNKVGVAEYVFSVLMVLAQQQGFSVFD- 123 Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K + I+GAG +G+ +A+ G+K +L D A +G ++ F L +K+ Sbjct: 124 KTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQA--QGDEREFTELETLLKQ------- 174 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAVFEDL 452 + + T + ++ A+ E L Sbjct: 175 -ADVITLHTPITRGGEWPTHHLIDAAILEQL 204 >4ND4-A nrPDB Length = 321 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 29/85 (34%), Gaps = 13/85 (15%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLK-TILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + +A++G+G +G IA + L +L D + + Sbjct: 5 RKIAVIGSGQIGGNIAYIVGKDNLADVVLFDIAEGIPQGKALDITHSMV----------- 53 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 S + G DY +D+VI Sbjct: 54 -MFGSTSKVIGTNDYADISGSDVVI 77 >1REO-A nrPDB Length = 486 Score = 39.3 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%) Query: 334 KESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDAT 393 + + + L + KH+ ++GAG+ G A V G + + +A+ Sbjct: 6 PLEECFRETDYEEFLEIARNGLKATSNPKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEAS 65 Query: 394 LTA 396 A Sbjct: 66 ERA 68 >3GGO-A nrPDB Length = 314 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 44/118 (37%), Gaps = 14/118 (11%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQ--QVFKGLNDKVKKKA 416 ++++ I+G G MG A+ G K D ++ + + +G K + Sbjct: 33 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVED 92 Query: 417 LTS-----FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDH 469 + F + +L Y E A V + S+K +++ ++E ++ Sbjct: 93 FSPDFVMLSSPVRTFREIAKKLSYILSEDA-----TVTDQGSVKGKLVYDLENILGKR 145 >2G5C-A nrPDB Length = 281 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 20/118 (16%), Positives = 44/118 (37%), Gaps = 14/118 (11%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQ--QVFKGLNDKVKKKA 416 ++++ I+G G MG A+ G K D ++ + + +G K + Sbjct: 1 MQNVLIVGVGFMGGSFAKSLRRSGFKGKIYGYDINPESISKAVDLGIIDEGTTSIAKVED 60 Query: 417 LTS-----FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDH 469 + F + +L Y E A V + S+K +++ ++E ++ Sbjct: 61 FSPDFVMLSSPVRTFREIAKKLSYILSEDA-----TVTDQGSVKGKLVYDLENILGKR 113 >5X6R-A nrPDB Length = 420 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLT-ALDRGQQQVFKGLNDKVKKKALTSF 420 + +AI+GAGL+G A +G L D LD + + K +N + + + + Sbjct: 29 ESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDPRLDTTKNKNLKSINLAISARGIDAL 88 Query: 421 E 421 + Sbjct: 89 K 89 >5U8W-A nrPDB Length = 481 Score = 38.9 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 26/56 (46%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL 417 K L ++GAG++G + V G + + +A L +Q+ K + K+ L Sbjct: 185 KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGL 240 >5ER0-A nrPDB Length = 518 Score = 38.9 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 31/162 (19%), Positives = 55/162 (33%), Gaps = 18/162 (11%) Query: 358 QKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKD----ATLTALDRG-QQQVFKGLNDKV 412 K+ K + ++GAG +GA +A+ G L D D + + D Sbjct: 194 AKEAKRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARVMPKYFDADFTDVIEQDYRDHG 253 Query: 413 KKKALTS--FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHC 470 + AL + LT + D +E D+ I + + +LK + P+ Sbjct: 254 VQLALGETVESFTDSATGLTIKTDKNSYE-TDLAILCIGFRPNT--DLLKGKVDMAPNGA 310 Query: 471 IFASNTSALPISEIAAVSKRPEKVIGMHYFSPVD---KMQLL 509 I + +I A +HY +P + L Sbjct: 311 IITDDYMRSSNPDIFAAGDS----AAVHY-NPTHQNAYIPLA 347 >4OQZ-A nrPDB Length = 289 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 33/87 (37%), Gaps = 6/87 (6%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 + + ++G G MG +A +D+G + L + R V +G + S Sbjct: 3 QSVTVIGLGPMGQAMAAAYLDRGYEVTLWN---RTASRADALVARGAKLAATPEQALSAN 59 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAV 448 I S + Y E A+ EAV Sbjct: 60 ELVILSLIDYDAMYGVLEGAE---EAV 83 >1PS9-A nrPDB Length = 671 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 26/139 (18%), Positives = 52/139 (37%), Gaps = 8/139 (5%) Query: 276 PFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKE 335 P V + + + + + A +++ ++G + C ++ + K Sbjct: 292 PQVADDILSRGDADMVSMARPFL-ADAELLSKAQSGRADEINTCIGCNQACLDQIFVGKV 350 Query: 336 SKALMGLYHGQVLCKKNKFG-APQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATL 394 + L+ C + K P K+LA++GAG G A + +G + L DA Sbjct: 351 TSCLVN----PRACHETKMPILPAVQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHS 406 Query: 395 TALDRGQQQVFKGLNDKVK 413 GQ + K + K + Sbjct: 407 EI--GGQFNIAKQIPGKEE 423 >6IHE-A nrPDB Length = 303 Score = 37.4 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 32/85 (37%), Gaps = 14/85 (16%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + +GAG +G IA ++ G + ++ D L DK + + +F Sbjct: 2 KVGFIGAGKIGQTIAYSALVSGAVDEAVIYDIIPE------------LPDKFEHELRHAF 49 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 I +N+ G D+V+ Sbjct: 50 ATKGIKANVLGTNSLDDVSGMDIVV 74 >4E84-A nrPDB Length = 352 Score = 37.0 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 17/114 (14%), Positives = 42/114 (36%), Gaps = 8/114 (7%) Query: 42 NYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGC--FI 99 ++ +++ N + + + + + A I + +L S+ G F Sbjct: 225 DWARYRGASLITPNRAELREVVGQWKSEDDLRARVANLRAELDIDALLLTRSEEGMTLFS 284 Query: 100 AGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAI------NGSCLG 147 AG +++ A + + +V+ V + + P+V A+ G +G Sbjct: 285 AGGELHAPALAREVFDVSGAGDTVIATVATMLGAGVPLVDAVVLANRAAGIVVG 338 >1MV8-A nrPDB Length = 436 Score = 37.0 bits (84), Expect = 0.032, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 38/86 (44%), Gaps = 13/86 (15%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD---RGQQQVFK-GLNDKVKKKALT 418 ++I G G +GA A +G + I D + T +D +G+ + + GL +++ T Sbjct: 2 RISIFGLGYVGAVCAGCLSARGHEVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQGRQT 61 Query: 419 SFERDSIFSNLTGQLDY-QGFEKADM 443 L+G D+ + +D+ Sbjct: 62 --------GRLSGTTDFKKAVLDSDV 79 >4OQY-A nrPDB Length = 290 Score = 37.0 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 39/110 (35%), Gaps = 14/110 (12%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 + + ++G G MG + +D G + + + V + A+ + Sbjct: 4 QSVTVIGLGPMGQAMVNTFLDNGHEVTVW-----------NRTASKAEALVARGAVLAPT 52 Query: 422 RDSIFS-NLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHC 470 + S N L ++ ++E V LS K V+ + + PD Sbjct: 53 VEDALSANELIVLSLTDYDAVYAILEPVTGSLSGK--VIANLSSDTPDKA 100 >5Y77-A nrPDB Length = 473 Score = 36.2 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 355 GAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKD--ATLTALDRGQQQ 403 G + + + I+GAGL G +A++ G + L + + + Sbjct: 2 GTATDNARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGR 52 >6BZ0-A nrPDB Length = 480 Score = 36.2 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 26/56 (46%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL 417 K L ++GAG++G + V G + ++ +A L + + K + K+ L Sbjct: 184 KRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGL 239 >2HMT-A nrPDB Length = 144 Score = 35.9 bits (81), Expect = 0.069, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 15/38 (39%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR 399 K A++G G G I + G + + D ++ Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 44 >4PRK-A nrPDB Length = 336 Score = 35.9 bits (81), Expect = 0.070, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 21/51 (41%), Gaps = 2/51 (3%) Query: 344 HGQVLCKKNKFGAPQKDV--KHLAILGAGLMGAGIAQVSVDKGLKTILKDA 392 + N ++ K + ++G G +G+ +AQ+ G K + D Sbjct: 127 NMDKGDFTNPDSLISNEIYNKTIGLIGVGHIGSAVAQIFSAMGAKVLAYDV 177 >4J90-A nrPDB Length = 222 Score = 35.9 bits (81), Expect = 0.072, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 15/38 (39%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR 399 K A++G G G I + G + + D ++ Sbjct: 7 KQFAVIGLGRFGGSICKELHRMGHEVLAVDINEEKVNA 44 >5BUT-A nrPDB Length = 288 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 15/38 (39%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR 399 K A++G G G I + G + + D ++ Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 44 Score = 35.9 bits (81), Expect = 0.074, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 15/38 (39%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR 399 K A++G G G I + G + + D ++ Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMGHEVLAVDINEEKVNA 186 >3LAD-A nrPDB Length = 476 Score = 35.9 bits (81), Expect = 0.077, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 25/55 (45%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL 417 L ++GAG++G + V G + + +A L +QV K + K+ L Sbjct: 182 KLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGL 236 >4ZGS-A nrPDB Length = 386 Score = 35.5 bits (80), Expect = 0.080, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 55/174 (31%), Gaps = 25/174 (14%) Query: 256 ISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKI----------- 304 + P DK + Y + + FV + V +++ K G+ L+ Sbjct: 64 VEPPLDKDTAQLARGYDVAVLFVNDRADASVIKELAK--AGVKLIALRCAGFDRVDLHAC 121 Query: 305 ----IDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKD 360 + VV+ + F ++ L Y + + G + Sbjct: 122 AEHGVRVVRVPTYSPESVAEHAVALIFA------LNRHLTDAYIRVRMGNYSLSGLVGVE 175 Query: 361 VKH--LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKV 412 ++H + ++G G +G A++ G K D + L++ + Sbjct: 176 MRHKVVGVVGTGAIGQQAARILKGIGCKVFAYDIKPNPAVEAMGIPYVSLDELL 229 >5N2I-A nrPDB Length = 232 Score = 35.5 bits (80), Expect = 0.094, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 35/105 (33%), Gaps = 20/105 (19%) Query: 348 LCKKNKFGAPQKDVKHLAILGA-GLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFK 406 K + P +A+LG G G G+A+ G + IL + ++ + Sbjct: 6 ASKSSPHDLPDVSGLSIAVLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGE 65 Query: 407 GLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFED 451 GL + G + E D+VI AV D Sbjct: 66 GLP-------------------VRGMDNAGAAEAGDVVIVAVPWD 91 >6C6P-A nrPDB Length = 458 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 23/45 (51%) Query: 355 GAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR 399 G ++ + I+GAG++G+ +A V G K + + L DR Sbjct: 1 GTSSQNDPEVIIVGAGVLGSALAAVLSRDGRKVTVIERDLKEPDR 45 >4E21-A nrPDB Length = 358 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 33/87 (37%), Gaps = 11/87 (12%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD-------RGQQQVFKGLNDKVKKK 415 + ++G G MGA + + G + ++ D + A+ G + + + VK + Sbjct: 24 QIGMIGLGRMGADMVRRLRKGGHECVVYDLNVNAVQALEREGIAGARSIEEFCAKLVKPR 83 Query: 416 A----LTSFERDSIFSNLTGQLDYQGF 438 + + DS+ +T L Sbjct: 84 VVWLMVPAAVVDSMLQRMTPLLAANDI 110 >5TR3-A nrPDB Length = 481 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 15/56 (26%), Positives = 25/56 (44%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL 417 K L ++GAG++G + V G + + +A T L V K + K+ L Sbjct: 185 KRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGL 240 >1VPD-A nrPDB Length = 299 Score = 35.1 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 46/131 (35%), Gaps = 27/131 (20%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 + +G G+MG +++ + G ++ D A+ D + A T+ Sbjct: 7 KVGFIGLGIMGKPMSKNLLKAGYSLVVSDRNPEAIA-----------DVIAAGAETASTA 55 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKE--VEAVIPDHCIFASNTSALP 480 +I E+ D++I + +K L E + + +S P Sbjct: 56 KAI------------AEQCDVIITMLPNSPHVKEVALGENGIIEGAKPGTVLIDMSSIAP 103 Query: 481 IS--EIAAVSK 489 ++ EI+ K Sbjct: 104 LASREISDALK 114 >3G0O-A nrPDB Length = 303 Score = 35.1 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 27/131 (20%), Positives = 47/131 (35%), Gaps = 26/131 (19%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 H+ I+G G MG G A+ + GL T D A + + + A + Sbjct: 9 HVGIVGLGSMGMGAARSCLRAGLSTWGADLNPQACA-----------NLLAEGACGAAAS 57 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKE--VEAVIPDH-CIFASNT-SA 478 F+ + L +V+ A ++ + E V ++ + S+T S+ Sbjct: 58 AREFAGVVDAL-------VILVVNAA----QVRQVLFGEDGVAHLMKPGSAVMVSSTISS 106 Query: 479 LPISEIAAVSK 489 EIAA Sbjct: 107 ADAQEIAAALT 117 >1Q1R-A nrPDB Length = 431 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 19/141 (13%), Positives = 42/141 (29%), Gaps = 25/141 (17%) Query: 315 GSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGA 374 +G + ++ F L ++++ + L ++G G +G Sbjct: 118 PVASGAVGKANNFRYLRTLEDAECIRRQLIAD---------------NRLVVIGGGYIGL 162 Query: 375 GIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLD 434 +A ++ + L D L+R + + ++A + D Sbjct: 163 EVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRTGTQVCGFEMSTD 222 Query: 435 YQGFEK----------ADMVI 445 Q AD+VI Sbjct: 223 QQKVTAVLCEDGTRLPADLVI 243 >3TL2-A nrPDB Length = 315 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 33/85 (38%), Gaps = 11/85 (12%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLK-TILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 K ++++GAG GA A + K L +L D + + + L + Sbjct: 9 KKVSVIGAGFTGATTAFLLAQKELADVVLVDI-PQLENPTKGKALDMLEASPVQG----- 62 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 +N+ G DY +D+V+ Sbjct: 63 ----FDANIIGTSDYADTADSDVVV 83 >1A5Z-A nrPDB Length = 319 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 30/143 (20%), Positives = 52/143 (36%), Gaps = 23/143 (16%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + I+G G +G+ A + KG + +L D + D + T F Sbjct: 2 KIGIVGLGRVGSSTAFALLMKGFAREMVLIDVDKKRAE----------GDALDLIHGTPF 51 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEA--VFEDL-SLKHRVLKEVEAVIPDHCIFASNTS 477 R + DY + +D+VI A V + + ++L V+ + A N S Sbjct: 52 TRRANIYA----GDYADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKE---IARNVS 104 Query: 478 ALPISEIAAVSKRPEKVIGMHYF 500 I V P V+ ++F Sbjct: 105 KYAPDSIVIVVTNPVDVL-TYFF 126 >1LTH-T nrPDB Length = 319 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 18/86 (20%), Positives = 39/86 (45%), Gaps = 15/86 (17%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTS 419 LA++GAG +G+ +A + +G+ + +L+D ++ + + + +S Sbjct: 8 TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA----------EVLDMQHGSS 57 Query: 420 FERDSIFSNLTGQLDYQGFEKADMVI 445 F ++ G D + ADMV+ Sbjct: 58 FYPTV---SIDGSDDPEICRDADMVV 80 >5JE8-A nrPDB Length = 302 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 18/42 (42%) Query: 355 GAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 G+ + +K + +G G MG +++ V G D A Sbjct: 1 GSAKDPMKKIGFIGLGNMGLPMSKNLVKSGYTVYGVDLNKEA 42 >3ZHB-A nrPDB Length = 309 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 22/57 (38%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++G GLMG +A + G T + + T + + K + A + Sbjct: 22 VTVIGLGLMGQALAGAFLGAGHPTTVWNRTAAKAEPLVARGAKSAGSVAEAVAASPL 78 >3G5Q-A nrPDB Length = 443 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 32/88 (36%), Gaps = 6/88 (6%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 ++ + ++GAGL G+ A + G+ L + + + V +L Sbjct: 1 MERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPKRMTPAHGT--DRFAEIVCSNSLGGE 58 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAV 448 +N G L + +V+EA Sbjct: 59 GE----TNAKGLLQAEMRRAGSLVMEAA 82 >6ABJ-A nrPDB Length = 345 Score = 34.7 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 21/151 (13%), Positives = 48/151 (31%), Gaps = 14/151 (9%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K + ++G G +G A++ G + + D + + L+ + + + S Sbjct: 161 KRVGVIGTGQIGETFARIMAGFGCELLAYDPYPNPRIQALGGRYLALDALLAESDIVSLH 220 Query: 422 R-----------DSIFSNLTGQLDYQGFEKADMVIEAV-FEDLSLKHRVLKEVEAVIPDH 469 + + + +V A E L ++ + Sbjct: 221 CPLTADTRHLIDAQRLATMKPGAMLINTGRGALVNAAALIEALKSGQLGYLGLDVYEEEA 280 Query: 470 CIFASNTSALPISE--IAAVSKRPEKVIGMH 498 IF + S P+ + +A + P V+ H Sbjct: 281 DIFFEDRSDQPLQDDVLARLLSFPNVVVTAH 311 >2YQ5-A nrPDB Length = 343 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 8/31 (25%), Positives = 16/31 (51%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDAT 393 + ++G G +G+ +A++ G K I D Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGAKVIAYDVA 180 >1SEZ-A nrPDB Length = 504 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 26/65 (40%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K +A++GAG+ G A GL + +A A + + GL +T E Sbjct: 14 KRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTESE 73 Query: 422 RDSIF 426 D F Sbjct: 74 GDVTF 78 >3KB6-A nrPDB Length = 334 Score = 34.3 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 26/52 (50%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKK 414 L ++G G +G+ +A + G+K + D + + V+ L++ +K+ Sbjct: 143 TLGVIGTGRIGSRVAMYGLAFGMKVLCYDVVKREDLKEKGCVYTSLDELLKE 194 >6QGL-A nrPDB Length = 512 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 30/153 (19%), Positives = 52/153 (33%), Gaps = 20/153 (13%) Query: 579 GFPVGAATLVDEVGVDVAKHVAEDLGKVFGERFGGGNPELLTQMVSKGFLGRKSG----- 633 G+ +GAA + G+ V + E + G P++L +S + RKS Sbjct: 6 GYAIGAAAISAVGGIGVGWTLREFEVVGSDDPAEGLTPDVLRNQLSDSVVKRKSNNQSTM 65 Query: 634 -------KGF----YIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQFRLVTRFV 682 G Y + ++LN+ +++ S + S E + Sbjct: 66 VDNQNILDGVEHTAYTEAKIAAIEELNAGSSE--SAVLSAANSAIDSYETTVRTNFYKSW 123 Query: 683 NEAVMCLQEGILATPAEGDIG--AVFGLGFPPC 713 NE V L+ A D+G + G P Sbjct: 124 NETVRELEAMTQTVIAHADVGLSYITDFGDPRF 156 >2UYY-A nrPDB Length = 316 Score = 34.3 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 12/37 (32%), Positives = 17/37 (45%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD 398 K + LG GLMG+GI + G + + T D Sbjct: 31 KKIGFLGLGLMGSGIVSNLLKMGHTVTVWNRTAEKCD 67 >2V8U-A nrPDB Length = 302 Score = 34.3 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 10/64 (15%), Positives = 21/64 (32%), Gaps = 2/64 (3%) Query: 64 LSKELHSEFSEVMNEIWASDQIRSAVLIS--SKPGCFIAGADINMLAACKTLQEVTQLSQ 121 S E + + + D V+ + F AG D A E+ ++++ Sbjct: 236 FSPEDYRDLGLIWKGASPEDGTEVVVVDGPPTGGPVFDAGHDAAEFAPEFHPGELYEIAK 295 Query: 122 EAQR 125 + Sbjct: 296 KLYE 299 >3WFI-A nrPDB Length = 312 Score = 34.3 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 44/128 (34%), Gaps = 16/128 (12%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKD--------ATLTALDRGQQQVFKGLNDKVKK 414 +AI GAG MG+ + G + +L D L K + K+ Sbjct: 2 KIAIAGAGAMGSRFGLMLHQSGNEVLLIDGWAEHVQQIKEHGLQANFNG--KEVEAKLPI 59 Query: 415 KALTSFERDSIFSNLTGQLDY----QGFEKADMVIEAVFEDLSLKHRVLKE--VEAVIPD 468 + E++ + + + +I+ E L L + + E +E +P Sbjct: 60 VLQSEVEKEDQVDLIILFTKAMQLEKMLQDIQSLIKKDTEVLCLLNGIGHEDIIEKFVPM 119 Query: 469 HCIFASNT 476 I+ NT Sbjct: 120 ENIYIGNT 127 >2R9Z-A nrPDB Length = 463 Score = 34.3 bits (77), Expect = 0.22, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 46/112 (41%), Gaps = 9/112 (8%) Query: 345 GQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQV 404 ++ + F A Q+ K +AI+GAG +G +A + G + + L + + Sbjct: 150 AELGITSDGFFALQQQPKRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLL 209 Query: 405 FKGLNDKVKKKAL--------TSFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 L + + + + + ERD+ + L Q D E D VI AV Sbjct: 210 SATLAENMHAQGIETHLEFAVAALERDAQGTTLVAQ-DGTRLEGFDSVIWAV 260 >5O3Z-A nrPDB Length = 263 Score = 33.9 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 32/87 (36%), Gaps = 3/87 (3%) Query: 361 VKHLAIL--GAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALT 418 ++ +A++ G +GA + + G + D + +R + Sbjct: 5 MEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGFKV 64 Query: 419 SFERDSIFSNLTGQLDYQGFEKADMVI 445 ++ L +D + F +AD+++ Sbjct: 65 DATDEASVEALARAVD-ETFGRADLLV 90 >3FG2-P nrPDB Length = 404 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 19/97 (19%), Positives = 34/97 (35%), Gaps = 8/97 (8%) Query: 360 DVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK---- 415 D KH+ ++GAG +G A + KGL+ + + + R Sbjct: 141 DKKHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVTPEISSYFHDRHSGAGIR 200 Query: 416 ---ALTSFERDSIFSNLTG-QLDYQGFEKADMVIEAV 448 + + E + +TG L D+V+ V Sbjct: 201 MHYGVRATEIAAEGDRVTGVVLSDGNTLPCDLVVVGV 237 >1X14-A nrPDB Length = 401 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 29/249 (11%), Positives = 80/249 (32%), Gaps = 20/249 (8%) Query: 204 GRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVA---ITFAKGLADKKISPKR 260 ++ K+G + G ++ ++ E+ + + K +P Sbjct: 25 ATPKTVEQLLKLGFTVAVESGAGQLASFDDKAFVQAGAEIVEGNSVWQSEIILKVNAPLD 84 Query: 261 DKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGY 320 D+ + + F+ ++ +K+ ++ + +D V S Sbjct: 85 DEIALLNP--GTTLVSFIWPAQNPELMQKLAERNVTVM-----AMDSVPRISRAQSLDAL 137 Query: 321 LCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVS 380 + G + + + + GQ+ P + ++GAG+ G + Sbjct: 138 SSMANIAGYRAIVEAAHEFGRFFTGQITAA---GKVPPA---KVMVIGAGVAGLAAIGAA 191 Query: 381 VDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGF-- 438 G D ++ Q + L K++A + + S+ + + + F Sbjct: 192 NSLGAIVRAFDTRPEVKEQVQSMGAEFLELDFKEEAGSGDGYAKVMSDAFIKAEMELFAA 251 Query: 439 --EKADMVI 445 ++ D+++ Sbjct: 252 QAKEVDIIV 260 >4K28-A nrPDB Length = 269 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 21/133 (15%), Positives = 46/133 (34%), Gaps = 21/133 (15%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGL-KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 K ++G G +G+ IA + G+ L D + + + + G Sbjct: 126 KRALVIGCGGVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNG------------- 172 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHR--VLKEVEAVIPDHCIFASNTSA 478 F LT + G E D+V A + + + + A + + A ++ Sbjct: 173 -----FPGLTVSTQFSGLEDFDLVANASPVGMGTRAELPLSAALLATLQPDTLVADVVTS 227 Query: 479 LPISEIAAVSKRP 491 I+ + +++ Sbjct: 228 PEITPLLNRARQV 240 >5JFC-L nrPDB Length = 474 Score = 33.5 bits (75), Expect = 0.37, Method: Composition-based stats. Identities = 26/180 (14%), Positives = 54/180 (30%), Gaps = 22/180 (12%) Query: 224 PLGPGLKPPEERTIEYLEEVAITFAKGLADKKIS---PKRDKGLVEKLTAYAMTIPFVRQ 280 +G ++ E + Y E+A+ A+ + + + + + + R Sbjct: 15 SVGERVRDFGEVNLGYSWELALREAERCLQCPVEYAPCIKGCPVHINIPGFIKALRENRD 74 Query: 281 QVYKKVEEKVR---------KQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELV 331 K V E +R T + P + G E Sbjct: 75 NPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIGKLERFVADYAR 134 Query: 332 MTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKD 391 ++L ++ K +++ K +AI+GAG G A G + + + Sbjct: 135 E--------HGIDDELLLEEIKG--IKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYE 184 >5VJ7-A nrPDB Length = 476 Score = 33.2 bits (74), Expect = 0.40, Method: Composition-based stats. Identities = 26/180 (14%), Positives = 54/180 (30%), Gaps = 22/180 (12%) Query: 224 PLGPGLKPPEERTIEYLEEVAITFAKGLADKKIS---PKRDKGLVEKLTAYAMTIPFVRQ 280 +G ++ E + Y E+A+ A+ + + + + + + R Sbjct: 15 SVGERVRDFGEVNLGYSWELALREAERCLQCPVEYAPCIKGCPVHINIPGFIKALRENRD 74 Query: 281 QVYKKVEEKVR---------KQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELV 331 K V E +R T + P + G E Sbjct: 75 NPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACVVGKVGDPINIGKLERFVADYAR 134 Query: 332 MTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKD 391 ++L ++ K +++ K +AI+GAG G A G + + + Sbjct: 135 E--------HGIDDELLLEEIKG--IKRNGKKVAIIGAGPAGLTCAADLAKMGYEVTIYE 184 >4ROS-A nrPDB Length = 320 Score = 33.2 bits (74), Expect = 0.41, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 31/85 (36%), Gaps = 13/85 (15%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGL-KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 +A++GAG +G +A ++ K L +L D + + Sbjct: 4 SKIALIGAGQIGGTLAHLAGLKELGDVVLFDIVDGVPQGKALDIAES------------A 51 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 D + +G DY AD+VI Sbjct: 52 PVDGFDAKYSGASDYSAIAGADVVI 76 >3ZZN-A nrPDB Length = 310 Score = 33.2 bits (74), Expect = 0.42, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 19/44 (43%), Gaps = 2/44 (4%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQV 404 + I+G+G++G+ A G+ + +L D + + Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDI 45 >3H2Z-A nrPDB Length = 382 Score = 33.2 bits (74), Expect = 0.42, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 34/82 (41%), Gaps = 2/82 (2%) Query: 368 GAGLMGAG-IAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIF 426 GAG +G G I ++ D G++ D LD + ++ + + + + + Sbjct: 7 GAGNIGRGFIGKLLADAGIQLTFADVNQVVLDALNARHSYQVHVVGETEQVDTVSGVNAV 66 Query: 427 SNLTGQLDYQGFEKADMVIEAV 448 S++ G + D+V AV Sbjct: 67 SSI-GDDVVDLIAQVDLVTTAV 87 >4A6N-B nrPDB Length = 398 Score = 33.2 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 13/66 (19%), Positives = 28/66 (42%), Gaps = 4/66 (6%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K++AI+G G +G +A++ G+ + + R +F G D K + + Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREAR----IFGGTLDLHKGSGQEAMK 82 Query: 422 RDSIFS 427 + + Sbjct: 83 KAGLLQ 88 >4FFM-A nrPDB Length = 363 Score = 33.2 bits (74), Expect = 0.50, Method: Composition-based stats. Identities = 15/62 (24%), Positives = 26/62 (41%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 +K + ++G L G A +S G+K +L D AL R F + + + L Sbjct: 1 MKTICLVGGKLQGFEAAYLSKKAGMKVVLVDKNPQALIRNYADEFYCFDVIKEPEKLLEL 60 Query: 421 ER 422 + Sbjct: 61 SK 62 >3VPX-A nrPDB Length = 364 Score = 32.8 bits (73), Expect = 0.52, Method: Composition-based stats. Identities = 16/62 (25%), Positives = 27/62 (43%) Query: 341 GLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRG 400 G+Y+G K FG K +A+ G G + + + ++G K I+ D A+ R Sbjct: 153 GIYYGMKAAAKEAFGDDSLAGKTVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRA 212 Query: 401 QQ 402 Sbjct: 213 VD 214 >2EW2-A nrPDB Length = 316 Score = 32.8 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 32/86 (37%), Gaps = 14/86 (16%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 +AI GAG MG+ + + G L D ++ K + F Sbjct: 5 KIAIAGAGAMGSRLGIMLHQGGNDVTLIDQWPAHIEA-----------IRKNGLIADFNG 53 Query: 423 DSIFSNL---TGQLDYQGFEKADMVI 445 + + +NL + + E+ D++I Sbjct: 54 EEVVANLPIFSPEEIDHQNEQVDLII 79 >4HTF-A nrPDB Length = 285 Score = 32.8 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 53/151 (35%), Gaps = 15/151 (9%) Query: 324 SQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDK 383 ++KF + L Q L + PQK L +L AG A ++ Sbjct: 34 AEKFSRNIYGTTKGQLRQAILWQDLDRVLAEMGPQK----LRVLDAGGGEGQTAIKMAER 89 Query: 384 GLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADM 443 G + IL D + +DR +Q +A + + D+ Sbjct: 90 GHQVILCDLSAQMIDRAKQA----------AEAKGVSDNMQFIHCAAQDVASHLETPVDL 139 Query: 444 VI-EAVFEDLSLKHRVLKEVEAVIPDHCIFA 473 ++ AV E ++ VL+ + +V+ + + Sbjct: 140 ILFHAVLEWVADPRSVLQTLWSVLRPGGVLS 170 >3WSV-A nrPDB Length = 322 Score = 32.8 bits (73), Expect = 0.55, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALD 398 + + I+G G +G IA +++G+ + +L D + Sbjct: 6 RKVVIVGTGFVGTSIAYAMINQGVANELVLIDVNQEKAE 44 >3VTF-A nrPDB Length = 444 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 28/84 (33%), Gaps = 1/84 (1%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + L++LG G +G A G + + D + ++R + +++ AL Sbjct: 21 MASLSVLGLGYVGVVHAVGFALLGHRVVGYDVNPSIVERLRAGRPHIYEPGLEE-ALGRA 79 Query: 421 ERDSIFSNLTGQLDYQGFEKADMV 444 S + A + Sbjct: 80 LSSGRLSFAESAEEAVAATDATFI 103 >2HQM-A nrPDB Length = 479 Score = 32.8 bits (73), Expect = 0.58, Method: Composition-based stats. Identities = 32/227 (14%), Positives = 76/227 (33%), Gaps = 8/227 (3%) Query: 208 RADRAKKMGLVDQLVEPLGPG-----LKPPEERTIEYLEEVA--ITFAKGLADKKISPKR 260 A RA G LVE G + ++ + Y ++A ++ A + P Sbjct: 26 SARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATRVSHANEYGLYQNLPLD 85 Query: 261 DKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGY 320 + L + ++ ++ + K+ + + +++ D Sbjct: 86 KEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARFNKDGNVEVQK-RDNTT 144 Query: 321 LCESQKFGELVMTKESKALMGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVS 380 S + ++ + ++ + F ++ K + ++GAG +G +A V Sbjct: 145 EVYSANHILVATGGKAIFPENIPGFELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVF 204 Query: 381 VDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFS 427 G +T L T L + + + + D K+ + + I Sbjct: 205 HGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVK 251 >5MH6-A nrPDB Length = 308 Score = 32.8 bits (73), Expect = 0.59, Method: Composition-based stats. Identities = 5/27 (18%), Positives = 15/27 (55%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTI 388 + + ++G G +G G+ + G++ + Sbjct: 136 ERVCVVGLGTLGRGVVDRAAALGMEVV 162 >5UYY-A nrPDB Length = 381 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 22/43 (51%), Gaps = 3/43 (6%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTIL--KDATLTALDRGQQ 402 K + ++G GL+G +A +++ K + D ++R ++ Sbjct: 18 KKVVLIGTGLIGGSLA-LAIKKDHDVTITGYDIFQEQVERAKE 59 >4A7P-A nrPDB Length = 446 Score = 32.8 bits (73), Expect = 0.64, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 31/87 (35%), Gaps = 5/87 (5%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 +A++G G +G D G + + D R + + + + + Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHEVVCVDKD----ARKIELLHQNVMPIYEPGLDALVAS 65 Query: 423 DSIFSNLTGQLD-YQGFEKADMVIEAV 448 + L+ D +G + AD V AV Sbjct: 66 NVKAGRLSFTTDLAEGVKDADAVFIAV 92 >3N58-A nrPDB Length = 464 Score = 32.8 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 29/230 (12%), Positives = 63/230 (27%), Gaps = 39/230 (16%) Query: 219 DQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAM---TI 275 + +++ G E ++ + ++ + + K + + I Sbjct: 125 NMILDDGGDATMYILIGARAEAGEDVLSNPQSEEEEVLFAQIKKRMAATPGFFTKQRAAI 184 Query: 276 PFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKE 335 V ++ V + Q KGL P P ++ T + + G Sbjct: 185 KGVTEETTTGVNRLYQLQKKGLLPFPAINVNDSVTKSKFDNKYGCK-------------- 230 Query: 336 SKALMGLYHGQVLCKKNKFGAPQKDVKHLAIL-GAGLMGAGIAQVSVDKGLKTILKDATL 394 + L + G +A++ G G +G G AQ G + + + Sbjct: 231 ----------ESLVDGIRRGTDVMMAGKVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDP 280 Query: 395 -TALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADM 443 AL + +T + S + + D Sbjct: 281 ICALQAAMDGF----------EVVTLDDAASTADIVVTTTGNKDVITIDH 320 >4Q28-A nrPDB Length = 113 Score = 32.4 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 13/79 (16%), Positives = 27/79 (34%), Gaps = 9/79 (11%) Query: 203 TGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDK 262 TGR + + A + GL+D + ++ EE+++ G + + R Sbjct: 22 TGRELSPEEAHRAGLID------WNMFVKLRSQECDW-EEISVKGPNGESS--VIHDRKS 72 Query: 263 GLVEKLTAYAMTIPFVRQQ 281 G + + Q Sbjct: 73 GKKFSIEEALQSGRLTPAQ 91 >4ZCC-A nrPDB Length = 336 Score = 32.4 bits (72), Expect = 0.70, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 14/28 (50%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKD 391 +AI+G G+ G AQ G + L D Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFD 32 >3NEP-X nrPDB Length = 314 Score = 32.4 bits (72), Expect = 0.78, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 34/85 (40%), Gaps = 14/85 (16%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++GAG +GA +A+ + + + ++ D K L+ + S Sbjct: 2 KVTVIGAGNVGATVAECVARQDVAKEVVMVDIKDGMPQG------KALDMR------ESS 49 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 + +TG DY E +D+ I Sbjct: 50 PIHGFDTRVTGTNDYGPTEDSDVCI 74 >5X68-A nrPDB Length = 391 Score = 32.4 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 20/145 (13%), Positives = 47/145 (32%), Gaps = 28/145 (19%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K +A++G GL+G+ A + + + +A + +F Sbjct: 15 KKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDT-------------------RVATFT 55 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAV-------IPDHCIFAS 474 R + Q + + + V + + ++ R++ + I + Sbjct: 56 RGRSINLALSHRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQYILSV 115 Query: 475 NTSALPISEIAAVSKRPEKVIGMHY 499 + L + A K P + MH+ Sbjct: 116 SRENLNKDLLTAAEKYPN--VKMHF 138 >1YB4-A nrPDB Length = 295 Score = 32.4 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 32/233 (13%), Positives = 73/233 (31%), Gaps = 46/233 (19%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 L +G G+MG+ +A G + + A + Sbjct: 5 KLGFIGLGIMGSPMAINLARAGHQLHVTTIGPVA------------------------DE 40 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKE---VEAVIPDHCIFASNTSAL 479 + + Q E AD++ V + ++ + E + + I + S++ Sbjct: 41 LLSLGAVNVETARQVTEFADIIFIMVPDTPQVEDVLFGEHGCAKTSLQGKTIV--DMSSI 98 Query: 480 PISEIAAVSKRPEKVIGMHYFSPVDKMQL------LEIITTEKTSKDTSASAVAVGLKQG 533 E ++R ++ + +PV ++ L I+ + + + G Sbjct: 99 SPIETKRFAQRVNEMGADYLDAPVSGGEIGAREGTLSIMVGGE--QKVFDRVKPLFDILG 156 Query: 534 KVIIVV-KDGPG---FYTTRCLAPMMSEV-----IRILQEGVDPKKLDSLTTS 577 K I +V +G G + + + E + + G DP ++ Sbjct: 157 KNITLVGGNGDGQTCKVANQIIVALNIEAVSEALVFASKAGADPVRVRQALMG 209 >4MOP-A nrPDB Length = 633 Score = 32.4 bits (72), Expect = 0.81, Method: Composition-based stats. Identities = 21/93 (22%), Positives = 38/93 (40%), Gaps = 12/93 (12%) Query: 357 PQKDVK-HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK 415 P D+K + I+G+G +G A+ V G K + D ++ GL KK Sbjct: 41 PGMDIKYDVVIVGSGPIGCTYARELVGAGYKVAMFDI---------GEIDSGLKIGAHKK 91 Query: 416 ALTSFER--DSIFSNLTGQLDYQGFEKADMVIE 446 +++ D + + GQL +V++ Sbjct: 92 NTVEYQKNIDKFVNVIQGQLMSVSVPVNTLVVD 124 >3Q3C-A nrPDB Length = 299 Score = 32.4 bits (72), Expect = 0.87, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 20/38 (52%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD 398 +K +A +G G MGA +A + G + D +A+D Sbjct: 2 MKQIAFIGLGHMGAPMATNLLKAGYLLNVFDLVQSAVD 39 >4UEJ-A nrPDB Length = 346 Score = 32.0 bits (71), Expect = 0.87, Method: Composition-based stats. Identities = 16/112 (14%), Positives = 31/112 (27%), Gaps = 14/112 (12%) Query: 340 MGLYHGQVLCKKNKFGAPQKDVKHLAILGAGLMG-AGIAQVSVDKGLKTILKDATLTALD 398 + +H C+ K++ I+GAG +G I D + L Sbjct: 150 LHAFHLAQGCEN----------KNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLA 199 Query: 399 RGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFE 450 + G +++ + S+ L +E E Sbjct: 200 LAK---SFGAMQTFNSSEMSAPQMQSVLRELRFNQLILETAGVPQTVELAVE 248 >3KKJ-A nrPDB Length = 336 Score = 32.0 bits (71), Expect = 0.87, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 14/28 (50%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKD 391 +AI+G G+ G AQ G + L D Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFD 32 >2LDB-A nrPDB Length = 317 Score = 32.0 bits (71), Expect = 0.89, Method: Composition-based stats. Identities = 19/114 (16%), Positives = 44/114 (38%), Gaps = 18/114 (15%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++GAG +GA +++G+ + +L DA + + + ++ + + Sbjct: 8 RVVVIGAGFVGASYVFALMNQGIADEIVLIDANES------KAIGDAMD--FNHGKVFAP 59 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFAS 474 + I+ DY AD+V+ + ++ V + IF S Sbjct: 60 KPVDIWHG-----DYDDCRDADLVVICAGANQKPGE---TRLDLVDKNIAIFRS 105 >1AHH-A nrPDB Length = 255 Score = 32.0 bits (71), Expect = 0.94, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 17/42 (40%), Gaps = 1/42 (2%) Query: 366 ILGAGL-MGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFK 406 I GAG +G IA G ++ D A + ++ + Sbjct: 16 ITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQ 57 >1Y6J-A nrPDB Length = 318 Score = 32.0 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 29/87 (33%), Gaps = 18/87 (20%) Query: 362 KHLAILGAGLMGAGIAQVSVD--KGLKTILKDA-TLTALDRGQQQVFKGLNDKVKKKALT 418 +AI+GAG +GA A + +L D A+ + GL Sbjct: 8 SKVAIIGAGFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMD-INHGL---------- 56 Query: 419 SFERDSIFSNLTGQLDYQGFEKADMVI 445 S G DY + D+++ Sbjct: 57 --PFMGQMSLYAG--DYSDVKDCDVIV 79 >5ZIK-A nrPDB Length = 303 Score = 32.0 bits (71), Expect = 0.98, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 38/125 (30%), Gaps = 17/125 (13%) Query: 366 ILGAGLMGAGIAQVSVDKGLKTILKDATLTALDR-----GQQQVFKGLNDKVKKKALTSF 420 ILGAG +G+ A GL L L R G V G A T Sbjct: 5 ILGAGSLGSLWAARLGRAGLPVRLILRDRQRLRRYQQAGGLSLVEDGQASLYPIAAETPD 64 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSL---------KHRVLKEVEAVIPDHCI 471 I L Y E A V + + L + V + C+ Sbjct: 65 GGQPIQRLLLACKAYDAEEAASSVAHRLAGNAELLLLQNGLGSQQAVAARLPR---SRCL 121 Query: 472 FASNT 476 FAS+T Sbjct: 122 FASST 126 >2W8Z-A nrPDB Length = 470 Score = 32.0 bits (71), Expect = 1.00, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 45/115 (39%), Gaps = 14/115 (12%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILK----DATLTALDRGQQQ-------VFKGLNDK 411 + ++G +MG +A KG + + T L + + + + +N Sbjct: 6 QIGVIGLAVMGKNLALNIESKGYSVAVYNRLREKTDEFLQEAKGKNIVGTYSIEEFVNAL 65 Query: 412 VKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIE---AVFEDLSLKHRVLKEVE 463 K + + + ++ T + EK D+VI+ F+D +++ L E+ Sbjct: 66 EKPRKILLMVKAGAPTDATIEQLKPHLEKGDIVIDGGNTYFKDTQRRNKELAELG 120 >6CI9-A nrPDB Length = 259 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 17/82 (20%), Positives = 30/82 (36%), Gaps = 5/82 (6%) Query: 365 AILGAGL--MGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 AI+ G +G GIA+ + G+ ++ LDR + G KV + Sbjct: 12 AIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLS-GTRGKVTAVRADVTDP 70 Query: 423 DSIFSNLTGQLDYQGFEKADMV 444 + + + G D+V Sbjct: 71 EDARRTVAETVSRHG--GLDIV 90 >3HWR-A nrPDB Length = 318 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 31/86 (36%), Gaps = 12/86 (13%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 +AI+GAG +G + G + IL + Q + + L + Sbjct: 21 KVAIMGAGAVGCYYGGMLARAGHEVILI---------ARPQHVQAIE--ATGLRLETQSF 69 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAV 448 D ++ D + AD+V+ V Sbjct: 70 DEQV-KVSASSDPSAVQGADLVLFCV 94 >2VHY-A nrPDB Length = 377 Score = 31.6 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 39/95 (41%), Gaps = 16/95 (16%) Query: 354 FGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVK 413 G P + + ++GAG G A+++ G + D + L +Q+ ++ Sbjct: 161 GGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKL----RQLDAEFCGRIH 216 Query: 414 KKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 + +++E + ++AD+VI AV Sbjct: 217 TRYSSAYELEG------------AVKRADLVIGAV 239 >5X1Y-B nrPDB Length = 554 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 35/91 (38%), Gaps = 7/91 (7%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK-----A 416 K L ++G+G +G + Q+ G + L + L ++ + + + ++ Sbjct: 250 KRLTVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLVK 309 Query: 417 LTSFERDSIFSNLTGQLDYQGFEKADMVIEA 447 +FER + Y + VIE+ Sbjct: 310 GATFERVEQSGEIKRV--YVTVNGSREVIES 338 >3ATQ-A nrPDB Length = 453 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATL 394 + I+G G G+ A +GLK +L D+ Sbjct: 9 VLIIGGGFAGSSAAYQLSRRGLKILLVDSKP 39 >2PA3-A nrPDB Length = 410 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 41/132 (31%), Gaps = 29/132 (21%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K L I+G G +G + ++ G+ D K L + Sbjct: 152 KKLGIIGYGHIGTQLGILAESLGMYVYFYDIE-------------------NKLPLGNAT 192 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIF--ASNTSAL 479 + S+L D V E+ S K+ + + +++ + AS + + Sbjct: 193 QVQHLSDLLNMSDVVSLH--------VPENPSTKNMMGAKEISLMKPGSLLINASRGTVV 244 Query: 480 PISEIAAVSKRP 491 I +A Sbjct: 245 DIPALADALASK 256 >3AXS-A nrPDB Length = 392 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 32/242 (13%), Positives = 71/242 (29%), Gaps = 32/242 (13%) Query: 502 PVDKMQLLEIITTEKTSKDTSASAVAVGLKQGKVIIVVKD---GPGFYTTRCLAPMMSEV 558 PV + + + K G+ + V D G R L S V Sbjct: 25 PVFYNPRMRVNR-----DLAVLGLEYLCKKLGR-PVKVADPLSASGIRAIRFLLE-TSCV 77 Query: 559 IRILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVAEDLGKVFG----ERFGGG 614 + + K ++ + +F + G++ + ++ G F + FG Sbjct: 78 EKAYANDISSKAIEIMKENFKLNNIPEDRYEIHGMEANFFLRKEWGFGFDYVDLDPFGTP 137 Query: 615 NPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPPKSEVSSDEDIQ 674 P + + +S G S + + M +A ++ Sbjct: 138 VPFIESVALSMKRGGILSLTA--TDTAPLSGTYPKTCMRRYMAR-----PLRNEFKHEV- 189 Query: 675 FRLVTRFVNEAVMCLQEGILATPAEGDIGAVFGLGFPPCLGGPFRFVDLYGAQKIVDRLK 734 + L + ++ A+ DI + + FV G +K+ ++ Sbjct: 190 ----------GIRILIKKVIELAAQYDIAMIPIFAYSHLHYFKLFFVKERGVEKVDKLIE 239 Query: 735 KY 736 ++ Sbjct: 240 QF 241 >2F1K-A nrPDB Length = 279 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 29/193 (15%), Positives = 52/193 (26%), Gaps = 57/193 (29%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 + ++G GL+GA +A +G I + R Q K + ++ +A Sbjct: 2 KIGVVGLGLIGASLAGDLRRRGHYLI-------GVSRQQSTCEKAVERQLVDEAGQDLSL 54 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPIS 482 + Q +L +E +IP A T ++ Sbjct: 55 LQTAKIIFLCTPIQL--------------------ILPTLEKLIPHLSPTAIVT---DVA 91 Query: 483 EIAAVSKRP-----EKVIGMH-----------------YFSPVDKMQLLEIITTEKTSKD 520 + P IG H + + + TE T + Sbjct: 92 SVKTAIAEPASQLWSGFIGGHPMAGTAAQGIDGAEENLFVNAPYV-----LTPTEYTDPE 146 Query: 521 TSASAVAVGLKQG 533 A +V G Sbjct: 147 QLACLRSVLEPLG 159 >3DC2-A nrPDB Length = 529 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 9/43 (20%), Positives = 18/43 (41%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQV 404 K + ++G G +G +AQ G + D ++ Q + Sbjct: 143 KTVGVVGLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGI 185 >1HL3-A nrPDB Length = 358 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 18/42 (42%), Gaps = 1/42 (2%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATL-TALDRGQQ 402 + L I+G G +G +A + G + D L ++R Sbjct: 172 ETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGIERALG 213 >3PEF-A nrPDB Length = 287 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 17/37 (45%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD 398 + +G G+MG+ +A+ V G + + + + Sbjct: 2 QKFGFIGLGIMGSAMAKNLVKAGCSVTIWNRSPEKAE 38 >1C0L-A nrPDB Length = 363 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 17/36 (47%), Gaps = 2/36 (5%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKT--ILKDATLT 395 K + +LG+G++G A + KG + +D Sbjct: 7 KRVVVLGSGVIGLSSALILARKGYSVHILARDLPED 42 >1GUZ-A nrPDB Length = 310 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 37/85 (43%), Gaps = 14/85 (16%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++GAG +GA A +K L + +L D + +G+ D + + F Sbjct: 2 KITVIGAGNVGATTAFRLAEKQLARELVLLDVVE-GIPQGKA------LDMYESGPVGLF 54 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 + + +TG DY +D+VI Sbjct: 55 D-----TKVTGSNDYADTANSDIVI 74 >5JXW-A nrPDB Length = 498 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 19/43 (44%), Gaps = 1/43 (2%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATL-TALDRGQQQ 403 K + +LG G +G G AQ G + I+ + AL + Sbjct: 272 KKIVVLGYGEVGKGCAQGLSGVGARVIVTEIDPICALQASMEG 314 >2EEZ-A nrPDB Length = 369 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 17/36 (47%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALD 398 + ILG G +G A++++ G + + D L Sbjct: 168 SVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQ 203 >1XDW-A nrPDB Length = 331 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 328 GELVMTKESKALMG-LYHGQVLCKKN---KFGAPQKDVKH--LAILGAGLMGAGIAQVSV 381 EL +T+ L Y KKN K+V++ + ++G G +G AQ+ Sbjct: 107 AELAVTQAMMLLRHTAYTTSRTAKKNFKVDAFMFSKEVRNCTVGVVGLGRIGRVAAQIFH 166 Query: 382 DKGLKTILKDA 392 G I +D Sbjct: 167 GMGATVIGEDV 177 >3KYB-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 17/35 (48%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 K + I+GAG GA I + +KG + + D Sbjct: 4 KKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHI 38 >3BF0-A nrPDB Length = 593 Score = 31.2 bits (69), Expect = 1.6, Method: Composition-based stats. Identities = 37/221 (16%), Positives = 62/221 (28%), Gaps = 66/221 (29%) Query: 134 TKPIVAAINGSCLGGGLEVAISCQYRIATKDRKT----VLGTPEV------LLGALPGAG 183 KP+V ++ G GG ++ Y +A T + G +G Sbjct: 371 GKPVVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTDGV 430 Query: 184 GTQRLP-----KMVGVPAALDMMLT----------------------------GRSIRAD 210 T L + + A L M L+ G Sbjct: 431 STSPLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQ 490 Query: 211 RAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTA 270 AK GLVD L + A+ A LA K+ + V++ T Sbjct: 491 DAKANGLVDSLGDFDD-----------------AVAKAAELA--KVKQWHLEYYVDEPTF 531 Query: 271 YAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTG 311 + + + V + + + + PAPL + Sbjct: 532 FDKVMDNMSGSVRAMLPDA----FQAMLPAPLASVASTVKS 568 >3LXD-A nrPDB Length = 415 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 22/70 (31%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K+ ++G G +G A V G+ L +A L R + + Sbjct: 153 KNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVDLR 212 Query: 422 RDSIFSNLTG 431 + + G Sbjct: 213 TGAAMDCIEG 222 >5U2O-A nrPDB Length = 576 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 16/103 (15%), Positives = 31/103 (30%) Query: 21 SRGYICRNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIW 80 +R Y+ + L R + + P+ ++ ++ L Sbjct: 430 NRAYLETALDQAHWLFGRNAAGTSFMTGIGMHSPQKPHHRLVASTQTLIPGLVVGGPNAQ 489 Query: 81 ASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEA 123 D I +L S P F A A ++ A + + A Sbjct: 490 GGDPIMDRLLRESDPRVFPAKAYVDDWEAYSVNEPAIDYTAPA 532 >3BHF-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 16/28 (57%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKD 391 + ++GAG MG +G+KT+L D Sbjct: 7 VIVVGAGSMGMAAGYQLAKQGVKTLLVD 34 >3CGD-A nrPDB Length = 480 Score = 30.8 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 18/39 (46%) Query: 358 QKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTA 396 V+ + I+G G +G +A+ V+ G K + + Sbjct: 183 TNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHI 221 >1GV0-A nrPDB Length = 310 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 37/85 (43%), Gaps = 14/85 (16%) Query: 363 HLAILGAGLMGAGIAQVSVDKGL--KTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + ++GAG +GA A +K L + +L D + +G+ D + + F Sbjct: 2 KITVIGAGNVGATTAFRLAEKQLARELVLLDVVE-GIPQGKA------LDMYESGPVGLF 54 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVI 445 + + +TG DY +D+V+ Sbjct: 55 D-----TKVTGSNDYADTANSDIVV 74 >2V3B-A nrPDB Length = 384 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 30/95 (31%), Gaps = 9/95 (9%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLT--------ALDRGQQQVFKGLNDKVK 413 + + +LGAGL+G A G + + A + Q +GL + Sbjct: 146 RRVLLLGAGLIGCEFANDLSSGGYQLDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFH 205 Query: 414 KKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 + L L D+V+ AV Sbjct: 206 LGPVL-ASLKKAGEGLEAHLSDGEVIPCDLVVSAV 239 >3NJ4-A nrPDB Length = 435 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 40/289 (13%), Positives = 84/289 (29%), Gaps = 45/289 (15%) Query: 255 KISPKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEK---VRKQTKGLYPAPLKIIDVVKTG 311 + + + E L T+ F + + + + YP L I + Sbjct: 101 PVYAWKGETDEEYLWCIEQTLYF-KDGPLNMILDDGGDLTNLIHTKYPQLLPGIRGISEE 159 Query: 312 IEQGSDAGYLCESQKFGELVMTKESKALMGLYHG------QVLCKKNKFGAPQKDVKHLA 365 G Y + ++ + ++ + L K +A Sbjct: 160 TTTGVHNLYKMMANGILKVPAINVNDSVTKSKFDNLYGCRESLIDGIKRATDVMIAGKVA 219 Query: 366 IL-GAGLMGAGIAQVSVDKGLKTILKDATL-TALDRGQQQVFKGLNDKVKKKALTSFERD 423 ++ G G +G G AQ G + I+ + AL + D+ ++ Sbjct: 220 VVAGYGDVGKGCAQALRGFGARVIITEIDPINALQAAMEGYEVTTMDEACQEGNIFVTTT 279 Query: 424 SIFSNLTGQLDYQGFEKA--------DMVI------EAVFEDLSLKHRV----------- 458 + G+ Q + A D+ I E E +++K +V Sbjct: 280 GCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNIKPQVDRYRLKNGRRI 339 Query: 459 -------LKEVEAVIPDHCIFASNTSALPISEIAAVSKRPEKV-IGMHY 499 L + + SN+ + + P+K +G+H+ Sbjct: 340 ILLAEGRLVNLGCAMGHPSFVMSNSFTNQVMAQIELWTHPDKYPVGVHF 388 >5OCM-A nrPDB Length = 291 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATL 394 + +LG GLMG +A + G T + + + Sbjct: 6 VTVLGLGLMGQALAGAFLKDGHATTVWNRSE 36 >1CF2-P nrPDB Length = 337 Score = 30.5 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 46/103 (44%), Gaps = 5/103 (4%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLN-DKVKKKALTS 419 +K +AI G G +G +A + ++ + + + KG + + + Sbjct: 1 MKAVAINGYGTVGKRVADAIAQQDDMKVIGVSKTRPDFEARMALKKGYDLYVAIPERVKL 60 Query: 420 FERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKH-RVLKE 461 FE+ I + G +D ++AD+VI+ E + K+ ++ KE Sbjct: 61 FEKAGI--EVAGTVD-DMLDEADIVIDCTPEGIGAKNLKMYKE 100 >1BG6-A nrPDB Length = 359 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 29/88 (32%), Gaps = 8/88 (9%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K A+LG G G A KG + D + +++ + L Sbjct: 5 KTYAVLGLGNGGHAFAAYLALKGQSVLAWDIDAQRI----KEIQDRGAIIAEGPGLAGTA 60 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEAVF 449 + ++ G + AD+++ V Sbjct: 61 HPDLLTSDIGL----AVKDADVILIVVP 84 >4THI-A nrPDB Length = 362 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 27/71 (38%), Gaps = 7/71 (9%) Query: 603 LGKVFGERFGGGNPELLTQMVSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLP 662 L + GE+ PE V + + SG+ F Y E + R M ++ Sbjct: 195 LINMAGEKPSQYVPEDGDAYVRASWFAQGSGRAFIGYSESMMR------MGDYAEQVRFK 248 Query: 663 PKSEVSSDEDI 673 P S+ +DI Sbjct: 249 P-ISSSAGQDI 258 >2QPO-A nrPDB Length = 184 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 13/72 (18%), Positives = 24/72 (33%), Gaps = 4/72 (5%) Query: 33 SALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLIS 92 + + +H GV+ V I P + ++ F + + S L+ Sbjct: 46 HSTMIVSHSGNGVEAHV----IERPEEMRKYIEEDTRGVFIDEVQFFNPSLFEVVKDLLD 101 Query: 93 SKPGCFIAGADI 104 F AG D+ Sbjct: 102 RGIDVFCAGLDL 113 >4DGK-A nrPDB Length = 501 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRG 400 +K ++GAG G +A G+ +L + R Sbjct: 1 MKPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRA 40 >2CZG-A nrPDB Length = 433 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 18/38 (47%) Query: 354 FGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKD 391 A + + +LG+G +G IA + G++ + D Sbjct: 12 GTATTDSAQKILLLGSGELGKEIAIEAQRLGVEVVAVD 49 >3DOJ-A nrPDB Length = 310 Score = 30.5 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 14/90 (15%), Positives = 30/90 (33%), Gaps = 3/90 (3%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + + LG G+MG ++ + G K + + L + + V G + + Sbjct: 21 MMEVGFLGLGIMGKAMSMNLLKNGFKVTVWN---RTLSKCDELVEHGASVCESPAEVIKK 77 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAVFE 450 + +I V+E + E Sbjct: 78 CKYTIAMLSDPCAALSVVFDKGGVLEQICE 107 >5IKL-B nrPDB Length = 537 Score = 30.5 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 33/181 (18%), Positives = 61/181 (33%), Gaps = 11/181 (6%) Query: 99 IAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGS-CLGGGLEVAISCQ 157 GA++N AA ++ + +A ++ P V ++GS GG + +S Sbjct: 146 SGGANLN-YAAEIFVEGARGFANQA-----RISAMGIPQVTVVHGSSTAGGAYQPGLSDY 199 Query: 158 YRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGL 217 + K L P +L A + L G + T + + A + L Sbjct: 200 VVVVRGKAKMFLAGPPLLKAATGEIASDEELG---GAELHAQVAGTAEYLAENDADGVRL 256 Query: 218 VDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKISPKRDKGLVEKLTAYAMTIPF 277 ++V L + P + E + L PK+ + E + A F Sbjct: 257 AREIVGMLPWNAQLPARPARSW-REPLYPVEELLGVVPADPKKPYDVREIVARIADGSEF 315 Query: 278 V 278 + Sbjct: 316 L 316 >3K30-A nrPDB Length = 690 Score = 30.5 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 45/134 (33%), Gaps = 8/134 (5%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFER 422 + ++GAG G A+ +G +L +A G+ L + + Sbjct: 393 RVLVVGAGPSGLEAARALGVRGYDVVLAEAGRDL--GGRVTQESALPGLSAWGRVKEYRE 450 Query: 423 DSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASNTSALPIS 482 + ++ + D ++E FE + + V H T+ALPI+ Sbjct: 451 AVLAELPNVEIYRESPMTGDDIVEFGFEHVITATGATWRTDGVARFH------TTALPIA 504 Query: 483 EIAAVSKRPEKVIG 496 E V + G Sbjct: 505 EGMQVLGPDDLFAG 518 >3UPY-A nrPDB Length = 445 Score = 30.5 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 14/102 (13%), Positives = 35/102 (34%), Gaps = 10/102 (9%) Query: 345 GQVLCKKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVD-KGLKTILKDATLTALDRGQQQ 403 + L + + G P + + ++GAG MG I +G++ + L + Sbjct: 11 ARDLAARAETGKPIR----IGLIGAGEMGTDIVTQVARMQGIEVGA--LSARRLPNTFKA 64 Query: 404 VFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVI 445 + D ++ +S + + D+++ Sbjct: 65 IRTAYGD---EENAREATTESAMTRAIEAGKIAVTDDNDLIL 103 >3PDU-A nrPDB Length = 287 Score = 30.5 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 8/35 (22%), Positives = 13/35 (37%) Query: 361 VKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLT 395 + LG G+MG +A V G + + Sbjct: 1 MTTYGFLGLGIMGGPMAANLVRAGFDVTVWNRNPA 35 >2ZLF-A nrPDB Length = 888 Score = 30.1 bits (66), Expect = 3.4, Method: Composition-based stats. Identities = 18/119 (15%), Positives = 40/119 (33%), Gaps = 6/119 (5%) Query: 561 ILQEGVDPKKLDSLTTSFGFPVGAATLVDEVGVDVAKHVA-EDLGKVFGERFGG-GNPEL 618 I EG+ + + G P L D ++ + + + +R Sbjct: 654 IWDEGMKQYLITQNGSIQGLPNVPQELKDL--YKTVWEISQKTIINMAADRSVYIDQSHS 711 Query: 619 LTQMVSKGFLGRKSGKGFYIYQEGVKR--KDLNSDMDSILASLKLPPKSEVSSDEDIQF 675 L + +G+ + FY +++G+K L + S + K + E++ Sbjct: 712 LNLFLRAPTMGKLTSMHFYGWKKGLKTGMYYLRTQAASAAIQFTIDQKIADQATENVAD 770 >4NAS-A nrPDB Length = 409 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 38/126 (30%), Gaps = 8/126 (6%) Query: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVA--AINGSCLGGGLEVAISCQYRIA 161 + L A L V + + + PI+A A++G L G I+ + Sbjct: 231 LAELGAGALLVNVVAYGYDVVADLARDPDVDVPILAHPAVSG-ALYGSPNYGIAADIVL- 288 Query: 162 TKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL 221 ++ +G P G+ L + + G A G+ L Sbjct: 289 ----GQLMRLAGADIGIFPSMYGSVTLGREATDRLLQHLRAEGPHKPVLPAPSAGIYPGL 344 Query: 222 VEPLGP 227 V L Sbjct: 345 VPRLYQ 350 >1PZF-A nrPDB Length = 331 Score = 30.1 bits (66), Expect = 3.5, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 18/32 (56%), Gaps = 1/32 (3%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLK-TILKDA 392 K +A++G+G++G + + + L +L D Sbjct: 10 KKVAMIGSGMIGGTMGYLCALRELADVVLYDV 41 >4OH1-A nrPDB Length = 351 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 11/55 (20%), Positives = 23/55 (41%), Gaps = 1/55 (1%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLK-TILKDATLTALDRGQQQVFKGLNDKVKKK 415 K +AI+GAG +G + Q++ G + D L+ + + ++ Sbjct: 175 KSVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAEEG 229 >3N6R-B nrPDB Length = 531 Score = 30.1 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 45/146 (30%), Gaps = 17/146 (11%) Query: 110 CKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTVL 169 T QE + + +++ ++T P+V I GG V S R Sbjct: 387 PGTSQEYGGVIKHGAKLLYAYGEATVPMVTVITRKAYGGAYVVMSSKHLR-----ADFNY 441 Query: 170 GTPEVLLGALPGAGGTQRL-------PKMVGVPAALDMMLTGRSIRADRAKKMGLVDQLV 222 P + + G T+ + P+ + A A G VD+++ Sbjct: 442 AWPTAEVAVMGAKGATEIIHRGDLGDPEKIAQHTADYEERFANPFVASE---RGFVDEVI 498 Query: 223 EPLGPGLKPPEERTIEYLEEVAITFA 248 +P + R L ++ Sbjct: 499 QPRSTRKR--VARAFASLRNKSVQMP 522 >1GPJ-A nrPDB Length = 404 Score = 30.1 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 34/86 (39%), Gaps = 3/86 (3%) Query: 362 KHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSFE 421 K + ++GAG MG +A+ VD+G++ +L +R + + V+ L Sbjct: 168 KTVLVVGAGEMGKTVAKSLVDRGVRAVL--VANRTYERAVELARDLGGEAVRFDELVDHL 225 Query: 422 RDSIFSNLTGQLDYQGFEKADMVIEA 447 S ++ D V EA Sbjct: 226 ARSDV-VVSATAAPHPVIHVDDVREA 250 >5U1O-A nrPDB Length = 458 Score = 30.1 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 39/106 (36%), Gaps = 8/106 (7%) Query: 350 KKNKFGAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLN 409 F ++ K +A++GAG + IA V G +T L + L + L Sbjct: 164 SNGFFDLAEQP-KRVAVVGAGYIAVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLV 222 Query: 410 DKVKKKALT-------SFERDSIFSNLTGQLDYQGFEKADMVIEAV 448 + ++ + T +LT L+ + D +I A+ Sbjct: 223 EVMEAEGPTLHTHSVPKEVVKEADGSLTLHLENGESQNVDQLIWAI 268 >3ICS-A nrPDB Length = 588 Score = 30.1 bits (66), Expect = 4.3, Method: Composition-based stats. Identities = 7/36 (19%), Positives = 19/36 (52%) Query: 358 QKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDAT 393 +K +H ++G G +G + + ++G++ L + Sbjct: 184 EKKPRHATVIGGGFIGVEMVENLRERGIEVTLVEMA 219 >3WTC-A nrPDB Length = 262 Score = 29.7 bits (65), Expect = 4.5, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 29/88 (32%), Gaps = 4/88 (4%) Query: 362 KHLAILGAGL-MGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 K A+ GA +G IA G IL D L ++V + L + Sbjct: 9 KIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEV-EALGRRAVALTADIS 67 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAV 448 RD S L + D+++ Sbjct: 68 NRDQFRSTLA--DAAKTLGGLDIMVNNA 93 >1LJU-A nrPDB Length = 131 Score = 29.7 bits (65), Expect = 4.8, Method: Composition-based stats. Identities = 12/67 (17%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 623 VSKGFLGRKSGKGFYIYQEGVKRKDLNSDMDSILASLKLPP--KSEVSSDEDIQFR--LV 678 +++G+ G+G+ +Y G++ +N + + + + D DI + LV Sbjct: 19 MAEGWGKEILGEGWNVYSAGIETHGVNPKAIEAMKEVDIDISNHTSDLIDNDILKQSDLV 78 Query: 679 TRFVNEA 685 ++A Sbjct: 79 VTLCSDA 85 >4WEQ-A nrPDB Length = 341 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 29/68 (42%), Gaps = 3/68 (4%) Query: 346 QVLCKKNKF---GAPQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQ 402 + L KK+++ P+ + I+G G++G A+ G K I + ++ + Sbjct: 143 EALAKKHEWRDLSQPEAADVTVGIMGMGVLGQDAARKLAAMGFKVIGWSRSKRVIEGVET 202 Query: 403 QVFKGLND 410 GL+ Sbjct: 203 YDAAGLDA 210 >3AEO-A nrPDB Length = 389 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 22/75 (29%) Query: 391 DATLTALDRGQQQVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEAVFE 450 D + + K L + + G +D A M AV E Sbjct: 294 DIAKKQMTGYGSTFLFEMKSFEAAKKLMEHLKVCTLAVSLGCVDTLIEHPASMTHAAVPE 353 Query: 451 DLSLKHRVLKEVEAV 465 ++ K + E+ + Sbjct: 354 NIMRKQGITPELVRI 368 >4C2K-A nrPDB Length = 417 Score = 29.7 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 41/117 (35%), Gaps = 2/117 (1%) Query: 467 PDHCIFASNTSALPISEIAAVSKRPEKVIGMHYFSPVDKMQLLEIITTEKTSKDTSASAV 526 D + A N S + AV E + H F+P+ ++ + ++ S Sbjct: 261 KDGTVTAGNASGVA-DGAGAVIIASEDAVKKHNFTPLARI-VGYFVSGCDPSIMGIGPVP 318 Query: 527 AVGLKQGKVIIVVKDGPGFYTTRCLAPMMSEVIRILQEGVDPKKLDSLTTSFGFPVG 583 A+ K + +KD AP V R L + ++ + G P+G Sbjct: 319 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLG 375 >5Z9Y-A nrPDB Length = 252 Score = 29.7 bits (65), Expect = 5.6, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 59/200 (29%), Gaps = 14/200 (7%) Query: 138 VAAINGSCLGGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAA 197 +A + + + G E+ R+ +L LG P LP G +A Sbjct: 27 LAVLEQALIASGTELTTVAIRRVDADGGTGLLDLLN-RLGITP-------LPNTAGSRSA 78 Query: 198 LDMMLTGRSIRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADKKIS 257 + +LT + A A V V L P + E++ L Sbjct: 79 AEAVLTAQL--AREALNTNWVKLEVIADERTLWPDAVELVRAAEQLVDDGFVVLPYTTDD 136 Query: 258 PKRDKGLVEKLTAYAMTIPFVRQQVYKKVEEKVRKQTKGLYPAPLKIIDVVKTGIEQGSD 317 P + L + A M + + P+ V+ GI SD Sbjct: 137 PVLARRLEDTGCAAVMPLGSPIGTGLGIANPHNIEMIVAGARVPV----VLDAGIGTASD 192 Query: 318 AGYLCESQKFGELVMTKESK 337 A E L+ + ++ Sbjct: 193 AALAMELGCDAVLLASAVTR 212 >6CAU-A nrPDB Length = 472 Score = 29.7 bits (65), Expect = 5.6, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 39/104 (37%), Gaps = 25/104 (24%) Query: 359 KDVKHLAILGAGLMGA-GIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKAL 417 + +KH+ +G G G GIA+V ++G K D K + Sbjct: 10 RRIKHIHFVGIGGAGMCGIAEVLANQGYKISGSDI---------------------KASK 48 Query: 418 TSFERDSIFSNLTGQLDYQGFEKAD-MVIEAV--FEDLSLKHRV 458 T+ + + + + + + A+ +V+ E+ +K + Sbjct: 49 TTQQLEENGIKVYIGHEAENIKNANVLVVSTAIDPENPEVKAAI 92 >5J5Z-A nrPDB Length = 496 Score = 29.3 bits (64), Expect = 6.1, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 42/121 (34%), Gaps = 7/121 (5%) Query: 330 LVMTKESKALMGLYHGQVLCKKNKFGAPQKDV-KHLAILGAGLMGAGIAQVSVDKGLKTI 388 + E G+ + + K V + + ++GAG++G + V G Sbjct: 168 IATGSEVTPFPGITIDEDTIVSSTGALSLKKVPEKMVVIGAGVIGVELGSVWQRLGADVT 227 Query: 389 LKDATLTALDRGQQ-QVFKGLNDKVKKKALTSFERDSIFSNLTGQLDYQGFEKADMVIEA 447 + G ++ K ++K+ + + + +TG K D+ IEA Sbjct: 228 AVEFLGHVGGVGIDMEISKNFQRILQKQGF----KFKLNTKVTGATKKSD-GKIDVSIEA 282 Query: 448 V 448 Sbjct: 283 A 283 >3CKY-A nrPDB Length = 301 Score = 29.3 bits (64), Expect = 6.3, Method: Composition-based stats. Identities = 7/32 (21%), Positives = 13/32 (40%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKTILKDATL 394 + +G G MG +A + +G+ D Sbjct: 6 KIGFIGLGAMGKPMAINLLKEGVTVYAFDLME 37 >5A9T-A nrPDB Length = 290 Score = 29.3 bits (64), Expect = 6.4, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 16/31 (51%) Query: 364 LAILGAGLMGAGIAQVSVDKGLKTILKDATL 394 + + G G MG+ +A +D+G + + + Sbjct: 8 VTVAGLGPMGSALAAALLDRGHDVTVWNRSP 38 >3NRA-A nrPDB Length = 407 Score = 29.3 bits (64), Expect = 6.5, Method: Composition-based stats. Identities = 12/69 (17%), Positives = 29/69 (42%) Query: 71 EFSEVMNEIWASDQIRSAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKL 130 E V + ++D+ R+ + ++ F AGA + + + V ++E +I Sbjct: 149 EMVPVQLDYVSADETRAGLDLTGLEEAFKAGARVFLFSNPNNPAGVVYSAEEIGQIAALA 208 Query: 131 EKSTKPIVA 139 + ++A Sbjct: 209 ARYGATVIA 217 >3DO5-A nrPDB Length = 327 Score = 29.3 bits (64), Expect = 6.6, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 48/117 (41%), Gaps = 9/117 (7%) Query: 363 HLAILGAGLMGAGIAQVSVDKGLKT--ILKDATLTALDRGQQQVF--KGLNDKVKKKALT 418 +AI+G G +G G+A++ + K + + + +TA+ + + L + ++ K T Sbjct: 4 KIAIVGFGTVGQGVAELLIRKREEIEKAIGEFKVTAVADSKSSISGDFSLVEALRMKRET 63 Query: 419 SFERDSIFSNLTGQLDYQGFEKADMVIEAVFEDLSLKHRVLKEVEAVIPDHCIFASN 475 RD ++ D++IEA + V EA+ + SN Sbjct: 64 GMLRDDA-----KAIEVVRSADYDVLIEASVTRVDGGEGVNYIREALKRGKHVVTSN 115 >5T5Q-A nrPDB Length = 247 Score = 28.9 bits (63), Expect = 8.1, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 31/88 (35%), Gaps = 5/88 (5%) Query: 362 KHLAILGA-GLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKKALTSF 420 + L + GA G +G IA++ G +L D LD + K +S Sbjct: 10 RTLVLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSA 69 Query: 421 ERDSIFSNLTGQLDYQGFEKADMVIEAV 448 + T L + F D ++ + Sbjct: 70 DDAEK----TVALAMERFGGIDFLVPSA 93 >1LU9-A nrPDB Length = 287 Score = 28.9 bits (63), Expect = 8.9, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 44/152 (28%), Gaps = 23/152 (15%) Query: 296 GLYPAPLKIIDVVKTGIEQGSDAGYLCESQKFGELVMTKESKALMGLYHGQVLCKKNKFG 355 G A ++ + VK + +S + L K G Sbjct: 67 GDMAAGERVFEAVKKRFFGPFRVSCMLDSNGSNTTAAAGVA-----------LVVKAAGG 115 Query: 356 APQKDVKHLAILGAGLMGAGIAQVSVDKGLKTILKDATLTALDRGQQQVFKGLNDKVKKK 415 + + K + + G G +G A + +G + +L L V K K Sbjct: 116 SVKGK-KAVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNKRF-----KV 169 Query: 416 ALTSFERDSIFSNLTGQLDYQGFEKADMVIEA 447 +T+ E S + + A V A Sbjct: 170 NVTAAETADDASR------AEAVKGAHFVFTA 195 >5IZ4-A nrPDB Length = 271 Score = 28.9 bits (63), Expect = 9.2, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 40/110 (36%), Gaps = 23/110 (20%) Query: 46 KGDVAVVRINS-----PNSKVNTLSKELHSE--FSEVMNEIWASDQIRSAVLISSKPGCF 98 KG V + ++ P+ +VN L+ + + V++ VL Sbjct: 177 KGAVNTLTLSLARNLAPHIRVNALAPGMVDDGLLLRVLDAAAYD-----GVLSR------ 225 Query: 99 IAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGG 148 + A K + ++++ A + T ++AA NG LGG Sbjct: 226 -----MTESAPLKRVSRPAEIAELAWFLTAHAPAITGQVIAAENGLLLGG 270 >1SKF-A nrPDB Length = 262 Score = 28.5 bits (62), Expect = 9.8, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 16/36 (44%), Gaps = 3/36 (8%) Query: 133 STKPIVAAINGSCLGGGLEVAISCQYRIATKDRKTV 168 TKP +AA+ G + G + Y A R++ Sbjct: 1 VTKPTIAAVGGYAMNNGTGTTL---YTKAADTRRST 33 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.130 0.326 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 25,784,048 Number of Sequences: 36641 Number of extensions: 1006859 Number of successful extensions: 4524 Number of sequences better than 10.0: 266 Number of HSP's better than 10.0 without gapping: 242 Number of HSP's successfully gapped in prelim test: 109 Number of HSP's that attempted gapping in prelim test: 3856 Number of HSP's gapped (non-prelim): 417 length of query: 763 length of database: 10,336,785 effective HSP length: 105 effective length of query: 658 effective length of database: 6,489,480 effective search space: 4270077840 effective search space used: 4270077840 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (28.9 bits)