BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P40394 (386 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1D1T-A nrPDB 757 0.0 1EE2-A nrPDB 567 e-162 1HSZ-A nrPDB 554 e-158 1U3W-A nrPDB 551 e-157 1HSO-A nrPDB 545 e-155 1MC5-A nrPDB 446 e-126 3COS-A nrPDB 442 e-124 1P0F-A nrPDB 416 e-117 1CDO-A nrPDB 401 e-112 1E3E-A nrPDB 394 e-110 4DLA-A nrPDB 381 e-106 4JJI-A nrPDB 375 e-104 4RQU-A nrPDB 354 4e-98 5TNX-A nrPDB 181 5e-46 1F8F-A nrPDB 158 5e-39 4CPD-A nrPDB 117 7e-27 3PII-A nrPDB 115 3e-26 5YLN-A nrPDB 114 7e-26 4Z6K-A nrPDB 106 2e-23 2DFV-A nrPDB 102 2e-22 3S2F-A nrPDB 101 5e-22 4ILK-A nrPDB 101 6e-22 3MEQ-A nrPDB 101 7e-22 4EEZ-A nrPDB 98 6e-21 1LLU-A nrPDB 96 4e-20 2DQ4-A nrPDB 94 8e-20 6N7L-A nrPDB 91 9e-19 2H6E-A nrPDB 90 2e-18 3GFB-A nrPDB 89 2e-18 5VM2-A nrPDB 88 5e-18 6FG0-A nrPDB 88 6e-18 1PL8-A nrPDB 88 7e-18 1H2B-A nrPDB 87 9e-18 3QE3-A nrPDB 87 1e-17 4GKV-A nrPDB 86 3e-17 3TWO-A nrPDB 84 1e-16 5ENV-A nrPDB 84 2e-16 5KIA-A nrPDB 83 3e-16 5YAT-A nrPDB 82 3e-16 2EER-A nrPDB 82 5e-16 4OH1-A nrPDB 82 6e-16 1E3J-A nrPDB 81 6e-16 3FSR-A nrPDB 80 1e-15 1YKF-A nrPDB 77 2e-14 1KEV-A nrPDB 76 2e-14 5VKT-A nrPDB 76 3e-14 4EJ6-A nrPDB 75 4e-14 4UEJ-A nrPDB 74 8e-14 3FPC-A nrPDB 74 9e-14 3FPL-A nrPDB 74 1e-13 5Z0C-A nrPDB 69 3e-12 5K1S-A nrPDB 69 4e-12 4JLW-A nrPDB 66 2e-11 1YQX-A nrPDB 66 3e-11 2OUI-A nrPDB 65 5e-11 1R37-A nrPDB 63 2e-10 1UUF-A nrPDB 63 2e-10 1KOL-A nrPDB 62 3e-10 3UOG-A nrPDB 61 1e-09 3IP1-A nrPDB 60 1e-09 3M6I-A nrPDB 60 2e-09 4OAQ-A nrPDB 59 4e-09 5H82-A nrPDB 57 2e-08 1Q1N-A nrPDB 55 4e-08 2DPH-A nrPDB 55 6e-08 3WLE-A nrPDB 54 9e-08 5H83-A nrPDB 51 9e-07 2VCY-A nrPDB 50 2e-06 5FI5-A nrPDB 49 4e-06 6DKH-A nrPDB 47 1e-05 1YB5-A nrPDB 47 2e-05 1WLY-A nrPDB 44 8e-05 6C49-A nrPDB 43 2e-04 2CDC-A nrPDB 42 5e-04 3JYN-A nrPDB 41 0.001 3FBG-A nrPDB 41 0.001 3QWB-A nrPDB 41 0.001 1QOR-A nrPDB 40 0.001 5A3V-A nrPDB 40 0.002 4A27-A nrPDB 39 0.005 3SLK-A nrPDB 37 0.011 4Y1B-A nrPDB 37 0.013 4RVS-A nrPDB 37 0.019 4J6F-A nrPDB 35 0.068 2WEK-A nrPDB 34 0.088 4DVJ-A nrPDB 33 0.21 2VWH-A nrPDB 33 0.22 4IDE-A nrPDB 31 1.1 5LB9-A nrPDB 31 1.1 1V9L-A nrPDB 30 1.5 2EGU-A nrPDB 30 1.6 4HDR-A nrPDB 30 1.8 1MV8-A nrPDB 30 2.4 2VN8-A nrPDB 29 2.7 6G1Y-A nrPDB 29 3.0 1JGT-A nrPDB 29 3.0 4A10-A nrPDB 29 3.3 2CF5-A nrPDB 29 3.4 3ZWA-A nrPDB 28 5.4 1ZCJ-A nrPDB 28 5.6 2XRX-A nrPDB 28 6.0 5ILO-A nrPDB 28 6.1 >1D1T-A nrPDB Length = 373 Score = 757 bits (1955), Expect = 0.0, Method: Compositional matrix adjust. Identities = 372/373 (99%), Positives = 373/373 (100%) Query: 14 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 73 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 60 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG Sbjct: 61 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 120 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 VLADGTTRFTCKGKPVHHF+NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG Sbjct: 121 VLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 180 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI Sbjct: 181 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 240 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML Sbjct: 241 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 300 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL Sbjct: 301 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 360 Query: 374 LNSGQSIRTVLTF 386 LNSGQSIRTVLTF Sbjct: 361 LNSGQSIRTVLTF 373 >1EE2-A nrPDB Length = 373 Score = 567 bits (1461), Expect = e-162, Method: Compositional matrix adjust. Identities = 262/372 (70%), Positives = 319/372 (85%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWEQK+PFSIEE+EVAPPK EVRIK++A GICR+DDHV+ GT+V+ Sbjct: 2 TAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGV 134 PVI GHEA GIVESIGEGVTTV+PGDKVIPLF+PQC +C+ C++P+GNLC+++ RG Sbjct: 62 PVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGT 121 Query: 135 LADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGA 194 + DGT+RFTC+GKP+HHF+ TSTF++YTVVDE SVAKID A+P EKVCL+GCGFSTGYG+ Sbjct: 122 MQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGS 181 Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 AVK KV GSTC VFGLGGVGLSVIMGCK+AGA+RIIG+D+NKDKF KA VGATEC++ Sbjct: 182 AVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVN 241 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 P+D KPI EVL+EM+ V ++FEVIG L+TM+ AL+ C YG SV+VGVPP ++ L+ Sbjct: 242 PQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLS 301 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELL 374 +PMLL +GRTWKG +FGG KS+D VPKLV +F+AKKF LD LITHVLPF+KI+EGF+LL Sbjct: 302 MNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLL 361 Query: 375 NSGQSIRTVLTF 386 SG+SIRT+LTF Sbjct: 362 RSGKSIRTILTF 373 >1HSZ-A nrPDB Length = 374 Score = 554 bits (1427), Expect = e-158, Method: Compositional matrix adjust. Identities = 259/373 (69%), Positives = 315/373 (84%), Gaps = 1/373 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWE K+PFSIE++EVAPPK EVRIK++A GICRTDDHV+ G +V+ Sbjct: 2 TAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 133 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ RG Sbjct: 62 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 L DGT RFTC+GKP+HHF+ TSTF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 122 TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 +AV KV PGSTC VFGLGGVGLS +MGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 182 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP+++ L Sbjct: 242 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 + +PMLL TGRTWKG V+GG KS++ +PKLV +F+AKKF LD LITHVLPF+KI+EGF+L Sbjct: 302 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 361 Query: 374 LNSGQSIRTVLTF 386 L+SG+SIRTVLTF Sbjct: 362 LHSGKSIRTVLTF 374 >1U3W-A nrPDB Length = 374 Score = 551 bits (1420), Expect = e-157, Method: Compositional matrix adjust. Identities = 259/373 (69%), Positives = 313/373 (83%), Gaps = 1/373 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GICR+D+HV+ G +V+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 133 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ RG Sbjct: 62 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 L DGT RFTC GKP+HHF+ STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 122 TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 +AVK KV PGSTC VFGLGGVGLSV+MGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 182 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ L Sbjct: 242 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNL 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 + +PMLL TGRTWKG +FGG KS++ VPKLV +F+AKKF LD LIT+VLPF+KI+EGF+L Sbjct: 302 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFDL 361 Query: 374 LNSGQSIRTVLTF 386 L SG+SIRTVLTF Sbjct: 362 LRSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 545 bits (1404), Expect = e-155, Method: Compositional matrix adjust. Identities = 256/373 (68%), Positives = 312/373 (83%), Gaps = 1/373 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GIC TDDHV+ GTMV+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 133 PVI+GHEA GIVES+GEGVTTVKPGDKVIPL +PQC +C C+NP+ N C+++D++ +G Sbjct: 62 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 L DGT+RFTC+ KP+HHF+ STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 122 TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 +AV KV PGSTC VFGLGGVGLS IMGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 182 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ L Sbjct: 242 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 + +PMLL TGRTWKG + GG KS++ VPKLV +F+AKKF LD LITHVLPF+KI+EGF+L Sbjct: 302 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 361 Query: 374 LNSGQSIRTVLTF 386 L+SG+SIRT+L F Sbjct: 362 LHSGKSIRTILMF 374 >1MC5-A nrPDB Length = 374 Score = 446 bits (1148), Expect = e-126, Method: Compositional matrix adjust. Identities = 227/371 (61%), Positives = 282/371 (76%), Gaps = 2/371 (0%) Query: 16 AGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-F 74 A +VIKCKAAV WE +P SIEEIEVAPPK EVRIKI+AT +C TD + + G F Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDIT-GRG 133 PVI+GHE GIVES+GEGVT +K GD VIPL++PQC EC C NP NLC + +T G+G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 ++ DGT+RFTCKGK + H+M TSTF+EYTVV + SVAKID AP +KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 AAV T K++PGS C VFGLGGVGL+VIMGCK AGASRIIG+D+NKDKF +A GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D +KPI EVL EMT V Y+FE IG+++ M AL +CH +G SVVVGV S + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 P L TGRTWKG FGG KS + VPKLV+E+++KK +D+ +TH L F +I++ FEL Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 374 LNSGQSIRTVL 384 ++SG+SIRTV+ Sbjct: 362 MHSGKSIRTVV 372 >3COS-A nrPDB Length = 381 Score = 442 bits (1137), Expect = e-124, Method: Compositional matrix adjust. Identities = 222/380 (58%), Positives = 273/380 (71%), Gaps = 6/380 (1%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS 72 MGT GKVIKCKAA+ WE +P IEE+EVAPPK EVRI+I+AT +C TD VI Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 73 -KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC-----IR 126 FPVIVGHEA GIVESIG GVT VKPGDKVIPL+ P CR+C C +P NLC ++ Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 127 SDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGC 186 S + + ++ D T+RFTCKGKPV+HF TSTF++YTVV + ++AKIDD A E+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 187 GFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 GFSTGYGAA+ KV PGSTC VFGLGGVGLS +MGCK+AGASRIIGID+N +KF KA A Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 247 VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGV 306 +GAT+C++P+D KPI EV+ E+T V + + G ETM AL +G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 307 PPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKK 366 +K LT P L GRT G FGG KS D +PKLVT++ KKF+LD L+TH LPF K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 367 ISEGFELLNSGQSIRTVLTF 386 ISE F+L+N G+SIRT+L F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >1P0F-A nrPDB Length = 373 Score = 416 bits (1070), Expect = e-117, Method: Compositional matrix adjust. Identities = 214/375 (57%), Positives = 279/375 (74%), Gaps = 3/375 (0%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS 72 M TAGK I CKAAV WE +P S+E I VAPPK EVRIKILA+GIC +D V+K + S Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 73 KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGR 132 KFPVI+GHEA G+VESIG GVT VKPGDKVIPLF+PQC C AC++ + N C ++D+ + Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 133 -GVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191 G++AD T+RFTC+GKP+++ M TSTFTEYTVV + +VAKID AP E CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 YGAAV T KV PGSTC VFGLGGVG S I+GCK+AGASRIIG+ +KDKF KA+ +GATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 C++PKD KPI EV+ E T V Y E G +ETM++AL S + G +VV+G+ + Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 L DP+LL TGR+ KG VFGG K ++V +LV +++ KK +++ L++ L +I++ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 372 ELLNSGQSIRTVLTF 386 ELL+SGQ +R+++ + Sbjct: 359 ELLSSGQGVRSIMIY 373 >1CDO-A nrPDB Length = 374 Score = 401 bits (1031), Expect = e-112, Method: Compositional matrix adjust. Identities = 198/374 (52%), Positives = 262/374 (70%), Gaps = 3/374 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTD-DHVIKGTMVSK 73 T GKVIKCKAAV WE +P IEEIEV P E+RIKI+ATG+C TD H+ +G Sbjct: 2 TVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKDG 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDIT-GR 132 FPV++GHE GIVES+G GVT +PG+KVIPLF+ QC EC C++P N C++ Sbjct: 62 FPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESP 121 Query: 133 GVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGY 192 V++ TRFTCKG+ V F+ TSTF++YTVV++ +VAKID +AP + VCL+GCG STG+ Sbjct: 122 DVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGF 181 Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 GAAV T KV+PGSTC VFGLG VGL+ +MGC SAGA RII +DLN DKFEKA GAT+ Sbjct: 182 GAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDF 241 Query: 253 ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKM 312 ++P D ++PIS+VLS+MT V ++ E +G++ M +AL SC +G SV+VG + Sbjct: 242 VNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHDV 301 Query: 313 LTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 372 T P+ L GRTWKG +FGG K +D VPK+V +L KK LD+ ITH +P + +++ + Sbjct: 302 ATR-PIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAID 360 Query: 373 LLNSGQSIRTVLTF 386 L+ G+ IRTVL+ Sbjct: 361 LMKHGKCIRTVLSL 374 >1E3E-A nrPDB Length = 376 Score = 394 bits (1013), Expect = e-110, Method: Compositional matrix adjust. Identities = 192/378 (50%), Positives = 262/378 (69%), Gaps = 7/378 (1%) Query: 14 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 73 GT GKVIKCKAA+ W+ P IEEIEV+PPK EVRI+++AT +C TD + + Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC-----IRSD 128 FPV++GHE GIVES+G GVT KPGDKVIP F PQC+ C C +P NLC + Sbjct: 61 FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYP 120 Query: 129 ITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGF 188 + ++ D T+RFTCKG+ ++HFM S+F++YTVV E+++A++DD A E+VCLIGCGF Sbjct: 121 TIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGF 180 Query: 189 STGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 S+GYGAA+ T KV PGSTC VFGLG VGLS I+GCK AGASRII ID+N +KF KA A+G Sbjct: 181 SSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALG 240 Query: 249 ATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP 308 AT+C++P++ KP+ +V++E+T V Y+ + G +T+ A+ + +G+ VVG Sbjct: 241 ATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGA-- 298 Query: 309 SAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKIS 368 +T + + GR+ G FGG KS D VP LV+++ KKFDLD L+TH LPF+ I+ Sbjct: 299 KVDEMTIPTVDVILGRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIN 358 Query: 369 EGFELLNSGQSIRTVLTF 386 + +L+ G+SIRT+LTF Sbjct: 359 DAIDLMKEGKSIRTILTF 376 >4DLA-A nrPDB Length = 396 Score = 381 bits (978), Expect = e-106, Method: Compositional matrix adjust. Identities = 191/374 (51%), Positives = 254/374 (67%), Gaps = 5/374 (1%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK- 73 T G+VI CKAAV WE +P IE+++VAPP+ EVR+K+L T +C TD + G Sbjct: 20 TQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGL 79 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC--IRSDITG 131 FP ++GHEA GIVES+GEGVT V+PGD VIP + +CREC C++ NLC +R+ TG Sbjct: 80 FPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRA-ATG 138 Query: 132 RGVLA-DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFST 190 GV+ D +RF+ GKP++HFM TSTF++YTVV + SVAKID AP EKVCL+GCG T Sbjct: 139 VGVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPT 198 Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 G GA T KV+PGS VFGLG VGL+V G K+AGASRIIGID++ KF++A G T Sbjct: 199 GLGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVT 258 Query: 251 ECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSA 310 E I+PK+ +PI +V+ ++T V Y+FE IG++ M AL CH +GTSV+VGV S Sbjct: 259 EFINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASG 318 Query: 311 KMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEG 370 + ++ P L TGR WKG FGG KSR VP LV ++L K+ +D+ ITH + I++ Sbjct: 319 QEISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKA 378 Query: 371 FELLNSGQSIRTVL 384 F+L++ G +R VL Sbjct: 379 FDLMHDGDCLRVVL 392 >4JJI-A nrPDB Length = 378 Score = 375 bits (962), Expect = e-104, Method: Compositional matrix adjust. Identities = 192/374 (51%), Positives = 252/374 (67%), Gaps = 5/374 (1%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK- 73 T G+VI CKAAV +E +P IE+++VAPP+ EVRIKIL T +C TD + G Sbjct: 2 TQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGL 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC--IRSDITG 131 FP I+GHEA GIVES+GEGVT V+ GD VIP + +CREC C++ NLC +RS TG Sbjct: 62 FPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRS-ATG 120 Query: 132 RGVLA-DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFST 190 G++ D +RF+ GKP++HFM TSTF++YTVV + SVAKID AP +KVCL+GCG T Sbjct: 121 VGIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPT 180 Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 G GA T KV+PGS +FGLG VGL+V G K+AGASRIIGID++ K+E A G Sbjct: 181 GLGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVN 240 Query: 251 ECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSA 310 E ++PKD KPI EV+ ++T V Y+FE IG++ M AL CH +GTSV+VGV S Sbjct: 241 EFVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASG 300 Query: 311 KMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEG 370 + ++ P L TGR WKG FGG KSR VP LV +++ K+ +D+ ITH L +I++ Sbjct: 301 QEISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKA 360 Query: 371 FELLNSGQSIRTVL 384 F+LL+ G +R VL Sbjct: 361 FDLLHEGTCLRCVL 374 >4RQU-A nrPDB Length = 375 Score = 354 bits (909), Expect = 4e-98, Method: Compositional matrix adjust. Identities = 169/371 (45%), Positives = 239/371 (64%), Gaps = 3/371 (0%) Query: 18 KVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT-MVSKFPV 76 ++I+CKAAV WE +P IEE+EVAPP+ EVRIKIL T +C TD + + FP Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 77 IVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC--IRSDITGRGV 134 I GHEA GIVES+GEGVT ++PGD V+P+F +C EC C + + N+C +R + G+ Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 135 LADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGA 194 + DG +RF+ GKP++HF+ TSTF+EYTVV VAKI+ AP +KVC++ CG STG GA Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 + K K G + +FGLG VGL G + AGASRIIG+D N +F++A G TEC++ Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 PKD KPI +V++EMT V + E G ++ MI A H +G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELL 374 PM RT KG FG K + D+P +V +++ K+ +L++ ITH +PF +I++ F+ + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 375 NSGQSIRTVLT 385 G+SIR ++T Sbjct: 362 LKGESIRCIIT 372 >5TNX-A nrPDB Length = 383 Score = 181 bits (459), Expect = 5e-46, Method: Compositional matrix adjust. Identities = 120/359 (33%), Positives = 182/359 (50%), Gaps = 15/359 (4%) Query: 33 PFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEG 92 PFSIE + P+ EV ++++ATG+C TD V P ++GHE G+VE++G Sbjct: 29 PFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVGPN 88 Query: 93 VTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRS-DITGRGVLADGTTRFT-CKGKPVH 150 V T+ GD V+ L C C +C G C + + G ADG T G+P+H Sbjct: 89 VKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEPLH 147 Query: 151 -HFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 209 HF S+F Y + E++ K+ AP E + +GCG TG GA + + V+ GS+ Sbjct: 148 DHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSFAS 207 Query: 210 FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEM 269 FG G VG+S +M + AGA+ II +D+ + A+ +GAT I+ K+ + + + E+ Sbjct: 208 FGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIREI 265 Query: 270 TGNNVGYTFEVIGH---LETMIDALASCHMNYGTSVVVGVPPSAKMLTYD-PMLLFTGRT 325 TG V Y E G L IDAL S GT VVG P +D LL G T Sbjct: 266 TGGGVDYALESTGLPAVLSQGIDALGS----RGTMGVVGAPKLGTKAEFDVNSLLLGGHT 321 Query: 326 WKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384 +G V G + +P+LV L +F D+L+ P ++I++ +SG +++ +L Sbjct: 322 IRGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLVK-FYPLEQINQAAADSSSGITLKPIL 379 >1F8F-A nrPDB Length = 371 Score = 158 bits (399), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 110/334 (32%), Positives = 166/334 (49%), Gaps = 18/334 (5%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGV 93 F ++ +++ P+ EV +K++ATG+C TD V P ++GHE +GI+E+IG V Sbjct: 19 FELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGSGIIEAIGPNV 78 Query: 94 TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGR---GVLADGTTRFTCKGKPV- 149 T ++ GD V+ L C +C C GN S+ GR G ++G + V Sbjct: 79 TELQVGDHVV-LSYGYCGKCTQCNT--GNPAYCSEFFGRNFSGADSEGNHALCTHDQGVV 135 Query: 150 -HHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCV 208 HF S+F Y + E++ K+ P E + +GCG TG GA + KV P S+ V Sbjct: 136 NDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALKVTPASSFV 195 Query: 209 VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSE 268 +G G VGLS ++ K GAS II +D+ + + E A +GAT I+ K + P++ + E Sbjct: 196 TWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK-TQDPVAAI-KE 253 Query: 269 MTGNNVGYTFEVIGHLETM---IDALASCHMNYGTSVVVGVPPSAKMLTYDPM-LLFTGR 324 +T V + E G E + +DAL G VVG P +D LL G+ Sbjct: 254 ITDGGVNFALESTGSPEILKQGVDALGI----LGKIAVVGAPQLGTTAQFDVNDLLLGGK 309 Query: 325 TWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLI 358 T G V G + +P+LV + KF DQL+ Sbjct: 310 TILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLV 343 >4CPD-A nrPDB Length = 347 Score = 117 bits (293), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 101/372 (27%), Positives = 168/372 (45%), Gaps = 41/372 (11%) Query: 25 AVLWEQKQPFSIEEIEVAPPKTK---EVRIKILATGICRTDDHVIKGTMVSKFPV----I 77 AV++E K+ +++E+ P+ + + +++ GIC +D H+ G K PV + Sbjct: 3 AVVFENKERVAVKEVNA--PRLQHPLDALVRVHLAGICGSDLHLYHG----KIPVLPGSV 56 Query: 78 VGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 +GHE G VE++GEG+ ++PGD V+ F C C CR NLC R + G G + Sbjct: 57 LGHEFVGQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPM-- 114 Query: 138 GTTRFTCKGKPVHHFMNTS-TFTEYTVVDESSV--AKIDDAAPPEKVCLIGCGFSTGYGA 194 F N E V S+V K+ PE+ G ST YG Sbjct: 115 --------------FGNLQGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGG 160 Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 ++ G+++PG + V G G VGL I + GAS+I+ ID ++ E+A ++GA + Sbjct: 161 LIQ-GQLRPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIPINA 219 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 +++ P+ V SE E +G T+ AL G VGV + Sbjct: 220 EQEN--PVRRVRSETNDEGPDLVLEAVGGAATLSLALEMVRPG-GRVSAVGVDNAPSF-- 274 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAK-KFDLDQLITHVLPFKKISEGFEL 373 P L +G GL + V LA + +++++H LP ++ G+EL Sbjct: 275 --PFPLASGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYEL 332 Query: 374 LNSGQSIRTVLT 385 + ++++ +L Sbjct: 333 FDRKEALKVLLV 344 >3PII-A nrPDB Length = 339 Score = 115 bits (289), Expect = 3e-26, Method: Compositional matrix adjust. Identities = 109/371 (29%), Positives = 162/371 (43%), Gaps = 43/371 (11%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFPVIVGH 80 KAAV+ + K+P I+E+E EV ++I A G+C TD H G + K P+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E GIVE +G GVT +K GD+V IP C C+ C + LC G V DG Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAGYSV--DG- 118 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY V KI D E+ I C T Y A TG Sbjct: 119 -----------------GYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTYKALKVTG 161 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISP--KD 257 KPG ++G+GG G + K+ G + ++ +D+ +K E A +GA ++P +D Sbjct: 162 -AKPGEWVAIYGIGGFGHVAVQYAKAMGLN-VVAVDIGDEKLELAKELGADLVVNPLKED 219 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML-TYD 316 + K + E + + + V + + + G V+VG+PP + +D Sbjct: 220 AAKFMKEKVGGV------HAAVVTAVSKPAFQSAYNSIRRGGACVLVGLPPEEMPIPIFD 273 Query: 317 PMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 +L G G + G K + + E K I V P +KI+E F+ + Sbjct: 274 TVL--NGIKIIGSIVGTRKDLQEALQFAAEGKVKT------IIEVQPLEKINEVFDRMLK 325 Query: 377 GQ-SIRTVLTF 386 GQ + R VLT Sbjct: 326 GQINGRVVLTL 336 >5YLN-A nrPDB Length = 356 Score = 114 bits (285), Expect = 7e-26, Method: Compositional matrix adjust. Identities = 96/332 (28%), Positives = 152/332 (45%), Gaps = 23/332 (6%) Query: 45 KTKEVRIKILATGICRTDDHVIKGTMVS-KFPVIVGHEATGIVESIGEGVTTVKPGDKVI 103 K + ++I+ T IC TD H+IKG + + + I+GHE GIVE +GEGV+ K GDKV+ Sbjct: 28 KPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEGIGIVEEVGEGVSNFKKGDKVL 87 Query: 104 PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTV 163 + C +C C+ C G L DG + V H NT T + Sbjct: 88 ISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQAEYLR---VPHADNTLYHTPEDL 144 Query: 164 VDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGC 223 DE+ V + D P TGY V GKV+PG + + G G VGL+ ++ Sbjct: 145 SDEALVM-LSDILP------------TGYEIGVLKGKVEPGCSVAIIGSGPVGLAALLTA 191 Query: 224 KSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGH 283 + +++I +DL+ ++ E A++ GAT ++ D K I E+ G V E +G Sbjct: 192 QFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEKAIKEIYDLTDGRGVDVAIEAVG- 250 Query: 284 LETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKL 343 + D GT GV K + +D L+ V GL S + P+L Sbjct: 251 IPATFDFCQKIIGVDGTVANCGV--HGKPVEFDLDKLWIRNI---NVTTGLVSTNTTPQL 305 Query: 344 VTEFLAKKFDLDQLITHVLPFKKISEGFELLN 375 + + K + ++L+TH +I + +E+ + Sbjct: 306 LKALESHKIEPEKLVTHYFKLSEIEKAYEVFS 337 >4Z6K-A nrPDB Length = 346 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 100/365 (27%), Positives = 162/365 (44%), Gaps = 48/365 (13%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAVL E Q IEE+++ P E+ +K+ A+G+C TD H ++G K P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G++ ++GEGVT VK GD+V + C C C LC +G V Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSV----- 116 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 +F EY + + + V I ++ ++ + C T Y +K Sbjct: 117 ---------------NGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKMT 160 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 KPG V+ G+GG+G + + G + + +D++ DK A +GA ++ K+ T Sbjct: 161 DTKPGDWVVISGIGGLGHMAVQYAIAMGLN-VAAVDIDDDKLAFAKKLGAKVTVNAKN-T 218 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALA-----SCHMNYGTSVVVGVPPSAKMLT 314 P + E+ G + G L T + A A S GT V G+PP ++ Sbjct: 219 DPAEYLQKEIGGAH--------GALVTAVSAKAFDQALSMLRRGGTLVCNGLPPGDFPVS 270 Query: 315 -YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 +D +L G T +G + G +R D+ + + A K + P + I++ FE Sbjct: 271 IFDTVL--NGITIRGSIVG---TRLDLQESLDMAAAGKV---KATVTAEPLENINDIFER 322 Query: 374 LNSGQ 378 + G+ Sbjct: 323 MRQGK 327 >2DFV-A nrPDB Length = 347 Score = 102 bits (255), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 104/357 (29%), Positives = 158/357 (44%), Gaps = 38/357 (10%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS----KFPVIVGHEATGIVESIGEGV 93 E++V P EV IK+LAT IC TD H+ + + K P I+GHE G V IG GV Sbjct: 20 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIGPGV 79 Query: 94 TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFM 153 ++ GD V C +C ACR ++C + I GV DG Sbjct: 80 EGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIF--GVDTDG--------------- 122 Query: 154 NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP--GSTCVVFG 211 F EY VV ++ K + PPE L G AV T P G + ++ G Sbjct: 123 ---VFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPISGKSVLITG 174 Query: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 G +GL I K++GA +I + + + E A VGA I+P + + EV+ G Sbjct: 175 AGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFEEDV-VKEVMDITDG 233 Query: 272 NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVF 331 N V E G + + L + G ++G+ P + ++ +++F T G Sbjct: 234 NGVDVFLEFSGAPKALEQGLQAV-TPAGRVSLLGLYPGKVTIDFNNLIIFKALTIYGITG 292 Query: 332 GGL-KSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSGQSIRTVLTF 386 L ++ V +L+ + K +LD +ITH F K E FEL+ +G++ + V Sbjct: 293 RHLWETWYTVSRLLQ---SGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFML 346 >3S2F-A nrPDB Length = 340 Score = 101 bits (252), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 74/254 (29%), Positives = 114/254 (44%), Gaps = 26/254 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAV+ P +I+E+ V P +V++KI A+G+C TD H G K P I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G V ++G GV+ VK GD+V +P C C C LC + TG V Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSV----- 118 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY V D + V + D ++ I C T Y +K Sbjct: 119 ---------------NGGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKVT 162 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 +PG V+ G+GG+G + ++ G R+ +D++ K A +GA ++ +D T Sbjct: 163 DTRPGQWVVISGIGGLGHVAVQYARAMGL-RVAAVDIDDAKLNLARRLGAEVAVNARD-T 220 Query: 260 KPISEVLSEMTGNN 273 P + + E+ G + Sbjct: 221 DPAAWLQKEIGGAH 234 >4ILK-A nrPDB Length = 359 Score = 101 bits (251), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 101/375 (26%), Positives = 175/375 (46%), Gaps = 53/375 (14%) Query: 25 AVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKG-TMVSKFPVIVGHEAT 83 ++L E+ SI E E+ P EVR+K+ GIC +D H+ +G +K+P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFT 143 G+++++GEGV + + G++V + C C C N+C + + GV ADG Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVC--TTLAVLGVHADG----- 135 Query: 144 CKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP 203 F+EY VV + KI +A + +I F+ AA TG +P Sbjct: 136 -------------GFSEYAVVPAKNAWKIPEAVADQYAVMIE-PFTI---AANVTGHGQP 178 Query: 204 --GSTCVVFGLGGVGLSVIMGCKSA-GASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 T +V+G G +GL+++ K +I D ++ EKA GA I+ +S Sbjct: 179 TENDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--NSQT 236 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML----TYD 316 P+ E +E + T +ID A+CH + V P+A+++ + + Sbjct: 237 PLGESFAE---KGIKPTL--------IID--AACHPSILKEAVTLASPAARIVLMGFSSE 283 Query: 317 PM-LLFTGRTWKG-CVFGGLKSRDDVPKLVTEFLAKKF-DLDQLITHVLPFKKISEGFEL 373 P ++ G T K +F + + P +V ++L+K ++LITH F+ +++ L Sbjct: 284 PSEVIQQGITGKELSIFSSRLNANKFP-VVIDWLSKGLIKPEKLITHTFDFQHVADAISL 342 Query: 374 --LNSGQSIRTVLTF 386 L+ + +LTF Sbjct: 343 FELDQKHCCKVLLTF 357 >3MEQ-A nrPDB Length = 365 Score = 101 bits (251), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 86/315 (27%), Positives = 134/315 (42%), Gaps = 32/315 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAV+ +P +I+E+ + P ++++ I A+G+C TD H +G K P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G V ++G GV VK GD+V IP C C C LC TG V Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQLNTGYSV----- 141 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 F EY V D + V + ++ + C T Y +K Sbjct: 142 ---------------NGGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGLKVT 185 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 KPG V+ G+GG+G + ++ G + + +D++ K + A +GAT ++ K Sbjct: 186 DTKPGDWVVISGIGGLGHMAVQYARAMGLN-VAAVDIDDRKLDLARRLGATVTVNAKTVA 244 Query: 260 KPISEVLSEMTGNNVGYTFEVIG--HLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP 317 P + + E G G + E + +A GT + G+PP L+ Sbjct: 245 DPAAYIRKETDGGAQGVLVTAVSPKAFEQALGMVARG----GTVSLNGLPPGDFPLSIFN 300 Query: 318 MLLFTGRTWKGCVFG 332 M+L G T +G + G Sbjct: 301 MVL-NGVTVRGSIVG 314 >4EEZ-A nrPDB Length = 348 Score = 98.2 bits (243), Expect = 6e-21, Method: Compositional matrix adjust. Identities = 86/313 (27%), Positives = 138/313 (44%), Gaps = 28/313 (8%) Query: 23 KAAVLWEQKQPFS-IEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHE 81 KAAV+ ++ + E E+ K E + + G+C TD HV G +K ++GHE Sbjct: 2 KAAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHE 61 Query: 82 ATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTT 140 GIV+ IG V++++ GD+V + F C C C + + C ++ G DG Sbjct: 62 GIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFC--REVKNAGYSVDGG- 118 Query: 141 RFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGK 200 E +V K+ D P + I C T Y A+K Sbjct: 119 -----------------MAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTY-KAIKVSG 160 Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 VKPG V+FG GG+G I K+ +++I +D+N+DK A +GA I+ D Sbjct: 161 VKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGD-VN 219 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMN-YGTSVVVGVPPSAKMLTYDPML 319 P+ E+ ++TG +G ++ + + A + G V V VP + L+ P + Sbjct: 220 PVDEI-KKITG-GLGVQSAIVCAVARIAFEQAVASLKPMGKMVAVAVPNTEMTLSV-PTV 276 Query: 320 LFTGRTWKGCVFG 332 +F G G + G Sbjct: 277 VFDGVEVAGSLVG 289 >1LLU-A nrPDB Length = 342 Score = 95.5 bits (236), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 110/254 (43%), Gaps = 26/254 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAV+ P IEE++V P +V +KI A+G+C TD H +G K P I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G V ++G GVT VK GD+V IP C C C LC TG V Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSV----- 122 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY + D + V + ++ I C T Y +K Sbjct: 123 ---------------NGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVY-KGLKQT 166 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 +PG + G+GG+G + ++ G + ID++ K E A +GA+ ++ + Sbjct: 167 NARPGQWVAISGIGGLGHVAVQYARAMGL-HVAAIDIDDAKLELARKLGASLTVNARQE- 224 Query: 260 KPISEVLSEMTGNN 273 P+ + ++ G + Sbjct: 225 DPVEAIQRDIGGAH 238 >2DQ4-A nrPDB Length = 343 Score = 94.4 bits (233), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 93/351 (26%), Positives = 152/351 (43%), Gaps = 38/351 (10%) Query: 41 VAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF----PVIVGHEATGIVESIGEGVTTV 96 V P E+ +++ A IC TD H+ K ++ P++ GHE +G+VE++G GV Sbjct: 20 VPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVTGHEFSGVVEAVGPGVRRP 79 Query: 97 KPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTS 156 + GD V C C ACR + ++C+ + I G V DG Sbjct: 80 QVGDHVSLESHIVCHACPACRTGNYHVCLNTQILG--VDRDGG----------------- 120 Query: 157 TFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT---GKVKPGSTCVVFGLG 213 F EY VV + A ++ P +V I +G AV T G G + ++ G G Sbjct: 121 -FAEYVVVPAEN-AWVNPKDLPFEVAAI----LEPFGNAVHTVYAGSGVSGKSVLITGAG 174 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 +GL M +++GA I+ D N + A A ++P + + EV+ +TG+ Sbjct: 175 PIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNPLEED--LLEVVRRVTGSG 231 Query: 274 VGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGG 333 V E G+ + L + + G + ++G+P L+ G T G G Sbjct: 232 VEVLLEFSGNEAAIHQGLMAL-IPGGEARILGIPSDPIRFDLAGELVMRGITAFG--IAG 288 Query: 334 LKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384 + + + + DL L+TH LP + E F LL SGQ+++ +L Sbjct: 289 RRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLASGQAVKVIL 339 >6N7L-A nrPDB Length = 353 Score = 90.9 bits (224), Expect = 9e-19, Method: Compositional matrix adjust. Identities = 93/337 (27%), Positives = 143/337 (42%), Gaps = 43/337 (12%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS--KFPVIVGH 80 KAAV+ +P I+E+ V P EV +K++A G+C TD H + G + K P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E GIV + G VK GD V +P C C+ C ITG L Sbjct: 75 EGVGIVVACGPD-AMVKEGDAVGVPWLYSACGCCDYC------------ITGWETL---- 117 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 C+ + + F EY + D V + ++ I C T Y +K Sbjct: 118 ----CEAQQNGGYSVDGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVY-KGLKET 172 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 + KPG + G+GG+G + K+ G + ID+ DK E A +GA ++ K +T Sbjct: 173 ETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVNAK-TT 230 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALA-----SCHMNYGTSVVVGVPP-SAKML 313 P + + E+ G + G L T + +A GT + G+PP S ++ Sbjct: 231 DPGTYLHKEVGGMH--------GALITAVSPIAFKQGIDVLRRKGTIALNGLPPGSFELP 282 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAK 350 ++ +L T +G + G K + E L K Sbjct: 283 IFETVLKRI--TVRGSIVGTRKDLQEALDFANEGLVK 317 >2H6E-A nrPDB Length = 344 Score = 89.7 bits (221), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 98/374 (26%), Positives = 167/374 (44%), Gaps = 53/374 (14%) Query: 19 VIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS---KFP 75 ++K KAA+L + +P SIE++ + P+ +EV I+I G+CRTD V KG + P Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 76 VIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVL 135 +I+GHE G + +GE + VK GD V+ C CR N+C I G+ Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQ--- 116 Query: 136 ADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESS-VAKIDDAAPPEKVCLIGCGFSTGYGA 194 T G F+EY +V S + K++ +P E L G +T GA Sbjct: 117 -------TTNG----------GFSEYMLVKSSRWLVKLNSLSPVEAAPLADAG-TTSMGA 158 Query: 195 AVK-----TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGAS-RIIGIDLNKDKFEKAMAVG 248 + + +P +V G+GG+ + I K+ + I+GI +K + A+ +G Sbjct: 159 IRQALPFISKFAEP--VVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFALELG 216 Query: 249 ATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP 308 A KD+ I++ L++ G ++ +++G ET + L G ++VG+ Sbjct: 217 ADYVSEMKDAESLINK-LTDGLGASI--AIDLVGTEETTYN-LGKLLAQEGAIILVGM-- 270 Query: 309 SAKMLTYDPMLLFTGRTWK----GCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPF 364 K ++ + F W G +G L +DV +L K + + +P Sbjct: 271 EGKRVSLEA---FDTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIK------VPL 321 Query: 365 KKISEGFELLNSGQ 378 I++ F L+ G+ Sbjct: 322 DDINKAFTNLDEGR 335 >3GFB-A nrPDB Length = 350 Score = 89.4 bits (220), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 93/354 (26%), Positives = 152/354 (42%), Gaps = 36/354 (10%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS----KFPVIVGHEATGIVESIGEGV 93 E++V P EV IK+LAT IC TD H+ + + K P I+GHE G V +G GV Sbjct: 21 EVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVGPGV 80 Query: 94 TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFM 153 ++ GD + C +C AC++ ++C + I GV DG Sbjct: 81 EDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIF--GVDMDG--------------- 123 Query: 154 NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP--GSTCVVFG 211 F Y +V + K PPE L G AV T P G + ++ G Sbjct: 124 ---VFAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGRSTLITG 175 Query: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 G +GL I K++GA +I + ++ + + A VGA ++P + P+ V+ G Sbjct: 176 AGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFEE-DPVKFVMDITDG 234 Query: 272 NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVF 331 V E G + + L + G ++G+ P + ++ +++F G Sbjct: 235 AGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFPREVTIDFNNLIIFKALEVHGIT- 292 Query: 332 GGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSGQSIRTVL 384 G + + + + K +LD +ITH F K E FEL+ +G++ + V Sbjct: 293 -GRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >5VM2-A nrPDB Length = 347 Score = 88.2 bits (217), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 89/340 (26%), Positives = 144/340 (42%), Gaps = 37/340 (10%) Query: 40 EVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFP---VIVGHEATGIVESIGEGVT 94 E+ PK EV IK+ GIC +D H + + K P + +GHE G V ++G V Sbjct: 20 EIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHECAGTVVAVGSRVR 79 Query: 95 TVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFM 153 KPGD+V I +P C C C N+C D T+ +G H+ Sbjct: 80 KFKPGDRVNIEPGVP-CGHCRYCLEGKYNICPDVDFMA--------TQPNYRGALTHYLC 130 Query: 154 NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 + +FT Y + D + P + G AA+ VKPG ++ G G Sbjct: 131 HPESFT-YKLPDNMDTMEGTLVEPA----------AVGMHAAM-LADVKPGKKIIILGAG 178 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTKPISEVLSEMTGN 272 +GL + CK GA+ I +D+ + + A +GAT I+ K+ T + +E G Sbjct: 179 CIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAKEDTIARCQQFTEDMGA 238 Query: 273 NVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFG 332 ++ FE G T+ A M G ++VG P A + + L VF Sbjct: 239 DI--VFETAGSAVTVKQA-PYLVMRGGKIMIVGTVPGASAINF---LKINREVTIQTVF- 291 Query: 333 GLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 372 + + P + + +FD+ ++TH+ ++ + + FE Sbjct: 292 --RYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >6FG0-A nrPDB Length = 352 Score = 88.2 bits (217), Expect = 6e-18, Method: Compositional matrix adjust. Identities = 72/258 (27%), Positives = 112/258 (43%), Gaps = 25/258 (9%) Query: 36 IEEIEVAPPKTKEVRIKILATGICRTDDHVI---KGTMVSKFPVIVGHEATGIVESIGEG 92 + +I P E+ +K+ A G+C +D V+ P+ +GHE G V +GEG Sbjct: 15 VVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLGHEGVGTVAELGEG 74 Query: 93 VTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHF 152 VT GD V C C+AC N C R+ G T G + Sbjct: 75 VTGFGVGDAVAVYGPWGCGACHACARGRENYCTRAADLG----------ITPPG-----Y 119 Query: 153 MNTSTFTEYTVVDES-SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFG 211 + + EY +VD + + I D P L G + + + + PGST VV G Sbjct: 120 GSPGSMAEYMIVDSARHLVPIGDLDPVAAAPLTDAGLTPYHAISRVLPLLGPGSTAVVIG 179 Query: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 +GG+G I ++ A+R+I +DL+ D+ A VGA + S ++ + E+TG Sbjct: 180 VGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAVK---SGAGAADAIRELTG 236 Query: 272 NNVGYT--FEVIGHLETM 287 G T F+ +G T+ Sbjct: 237 GQ-GATAVFDFVGAQSTI 253 >1PL8-A nrPDB Length = 356 Score = 87.8 bits (216), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 93/356 (26%), Positives = 153/356 (42%), Gaps = 32/356 (8%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHEATGIVESI 89 +E + P EV +++ + GIC +D H + G + K P+++GHEA+G VE + Sbjct: 19 LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKV 78 Query: 90 GEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPV 149 G V +KPGD+V E A R D C GR L+ F C P Sbjct: 79 GSSVKHLKPGDRV-------AIEPGAPREND-EFCK----MGRYNLSPSI--FFCATPP- 123 Query: 150 HHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 209 + + + + K+ D E+ LI S G A + G V G +V Sbjct: 124 ----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGI-HACRRGGVTLGHKVLV 177 Query: 210 FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTKPISEVLSE 268 G G +G+ ++ K+ GA++++ DL+ + KA +GA + K+S + I+ + Sbjct: 178 CGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQEIARKVEG 237 Query: 269 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKG 328 G T E G E I A + GT V+VG+ +T P+L R Sbjct: 238 QLGCKPEVTIECTG-AEASIQAGIYATRSGGTLVLVGL---GSEMTTVPLLHAAIREVD- 292 Query: 329 CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384 + G + + P ++ +K ++ L+TH P +K E FE G ++ +L Sbjct: 293 -IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKIML 347 >1H2B-A nrPDB Length = 359 Score = 87.4 bits (215), Expect = 9e-18, Method: Compositional matrix adjust. Identities = 77/295 (26%), Positives = 131/295 (44%), Gaps = 30/295 (10%) Query: 19 VIKCKAAVLWEQKQPFSIEEIEVAPPKTK-EVRIKILATGICRTDDHVIKGT----MVSK 73 V + KAA L E +P IE+++ + + +V ++I G+C TD H+++G + K Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRE--CNACRNPDGNLCIRSDITG 131 P +GHE G +E + EGV ++ GD VI P + C ACR + C + G Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVI--LHPAVTDGTCLACRAGEDMHCENLEFPG 130 Query: 132 RGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191 + DG FM TS + + + S K+ + AP L G T Sbjct: 131 LNI--DGG---------FAEFMRTSHRSVIKLPKDISREKLVEMAP-----LADAGI-TA 173 Query: 192 YGAAVKTGK-VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 Y A K + + PG+ + G+GG+G + K + +I +D+ ++K + A +GA Sbjct: 174 YRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLGAD 233 Query: 251 ECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVG 305 + + P+ +V+ G V + +G T +D G ++VG Sbjct: 234 HVVDAR--RDPVKQVMELTRGRGVNVAMDFVGSQAT-VDYTPYLLGRMGRLIIVG 285 >3QE3-A nrPDB Length = 355 Score = 87.0 bits (214), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 93/356 (26%), Positives = 158/356 (44%), Gaps = 32/356 (8%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHEATGIVESI 89 +E + P EV +K+ + GIC +D H + G V K P+++GHEA+G V + Sbjct: 18 LRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHEASGTVVKV 77 Query: 90 GEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPV 149 G V ++PGD+V + A R D C GR L+ T F C P Sbjct: 78 GSLVRHLQPGDRV-------AIQPGAPRQTD-EFCK----IGRYNLS--PTIFFCATPP- 122 Query: 150 HHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 209 + + + + K+ D E+ LI S G A + G V G+ +V Sbjct: 123 ----DDGNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGIHACRRAG-VTLGNKVLV 176 Query: 210 FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTKPISEVLSE 268 G G +GL ++ K+ GA++++ DL+ + KA VGA + +S + I++ + Sbjct: 177 CGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPEEIAKKVEG 236 Query: 269 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKG 328 + G+ T E G +ET I A + GT V+VG+ +T P++ R Sbjct: 237 LLGSKPEVTIECTG-VETSIQAGIYATHSGGTLVLVGL---GSEMTSVPLVHAATREVD- 291 Query: 329 CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384 + G + + P ++ +K ++ L+TH P +K E FE G ++ ++ Sbjct: 292 -IKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGLKVMI 346 >4GKV-A nrPDB Length = 336 Score = 85.9 bits (211), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 87/299 (29%), Positives = 133/299 (44%), Gaps = 34/299 (11%) Query: 45 KTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKV-I 103 K E +K+ G+C TD HV G K VI+GHE G+V +G GVT++KPGD+ + Sbjct: 23 KHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEGIGVVAEVGPGVTSLKPGDRASV 82 Query: 104 PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTV 163 F C C C + + LC RS + G DG C +Y V Sbjct: 83 AWFYEGCGHCEYCNSGNETLC-RS-VKNAGYSVDGGMAEEC-----------IVVADYAV 129 Query: 164 VDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGC 223 K+ D I C T Y AVK K++PG ++GLGG+G + Sbjct: 130 -------KVPDGLDSAAASSITCAGVTTY-KAVKLSKIRPGQWIAIYGLGGLGNLALQYA 181 Query: 224 KSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGN--NVGYTFEVI 281 K+ +++I ID+N ++ + A +GA I+ T+ ++++ E TG T Sbjct: 182 KNVFNAKVIAIDVNDEQLKLATEMGADLAINSH--TEDAAKIVQEKTGGAHAAVVTAVAK 239 Query: 282 GHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDV 340 + +DA+ + G V VG+PP + L P L+ G G + G +R D+ Sbjct: 240 AAFNSAVDAVRAG----GRVVAVGLPPESMSLDI-PRLVLDGIEVVGSLVG---TRQDL 290 >3TWO-A nrPDB Length = 348 Score = 84.0 bits (206), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 81/331 (24%), Positives = 140/331 (42%), Gaps = 41/331 (12%) Query: 20 IKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-FPVIV 78 ++ K ++ + + F + ++V I IL GIC +D H +P+I Sbjct: 3 VQSKGFAIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIP 62 Query: 79 GHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 GHE GI++ +G+GV K GD V + F+ C+ C C+ C + T Sbjct: 63 GHEIAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKVVFT------- 115 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVK 197 + C + + ++ VVDE+ V +D AP EKV + C T Y + +K Sbjct: 116 ----YDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTY-SPLK 170 Query: 198 TGKVKPGSTCVVFGLGGVG-----LSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 KV G+ V G GG+G +V MG + + +R N+ K + A+++G Sbjct: 171 FSKVTKGTKVGVAGFGGLGSMAVKYAVAMGAEVSVFAR------NEHKKQDALSMGVKHF 224 Query: 253 IS-PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP--S 309 + PK + + ++S + + + D L N G +VG+PP Sbjct: 225 YTDPKQCKEELDFIISTIPTHY------------DLKDYLKLLTYN-GDLALVGLPPVEV 271 Query: 310 AKMLTYDPMLLFTGRTWKGCVFGGLKSRDDV 340 A +L+ + R G + GG+K ++ Sbjct: 272 APVLSVFDFIHLGNRKVYGSLIGGIKETQEM 302 >5ENV-A nrPDB Length = 347 Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 76/293 (25%), Positives = 117/293 (39%), Gaps = 28/293 (9%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFPVIVGH 80 K + +E ++I V PK E+ I + +G+C TD H G + K P++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G+V +GE V K GD I C C C + + C +D++G Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSG-------- 118 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + + +F +Y D A I +V I C T Y A+K+ Sbjct: 119 ------------YTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKSA 165 Query: 200 KVKPGSTCVVFG-LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 + G + G GG+G + K+ G R++GID + K E ++G I Sbjct: 166 NLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTKE 224 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 + VL G G + E I+A GT+V+VG+P AK Sbjct: 225 KDIVGAVLKATDGGAHGVINVSVS--EAAIEASTRYVRANGTTVLVGMPAGAK 275 >5KIA-A nrPDB Length = 351 Score = 82.8 bits (203), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 92/348 (26%), Positives = 147/348 (42%), Gaps = 41/348 (11%) Query: 47 KEVRIKILATGICRTDDHVIKGTMVSK----FPVIVGHEATGIVESIGEGVTTVKPGDKV 102 +V IKI T IC TD H+ K ++ P+ VGHE G + +G+ V GD+V Sbjct: 34 NDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHVGHEYVGEIVEMGQEVRGFSIGDRV 93 Query: 103 IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYT 162 C C CR +LC + G GV +G F EY Sbjct: 94 SGEGHITCGFCRNCRAGRRHLC--RNTVGVGVNREGA------------------FAEYL 133 Query: 163 VVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP--GSTCVVFGLGGVGLSVI 220 + + KI PPE + F +G A T G ++ G G +G+ + Sbjct: 134 AIPAFNAFKI----PPEISDDLAAIFDP-FGNATHTALSFNLVGEDVLITGAGPIGVMAV 188 Query: 221 MGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTKPISEVLSEMTGNNVGYTFE 279 K GA ++ D+N + + A +GAT ++ ++S + + L G +VG E Sbjct: 189 AIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRESLRDVMADLHMTEGFDVG--LE 246 Query: 280 VIGHLETMIDALASCHMNYGTSV-VVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRD 338 + G L S MN+G V ++G+PP+ + ++ ++F G KG G + + Sbjct: 247 MSGVPSAFTSLLES--MNHGGKVALLGIPPAQTAIDWN-QVIFKGLEIKGIY--GREMFE 301 Query: 339 DVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF 386 K+V L DL +ITH +GF + SG+S + +L + Sbjct: 302 TWYKMVA-MLQSGLDLSPIITHRFAVDDYEKGFAAMLSGESGKVILDW 348 >5YAT-A nrPDB Length = 350 Score = 82.4 bits (202), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 79/296 (26%), Positives = 123/296 (41%), Gaps = 36/296 (12%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFPVIVGH 80 KA + P ++I V PK+ E+ I + +G+C TD H KG + +K P++ GH Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGH 69 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G+V + GE VT + GD I C C C + C ++D++G Sbjct: 70 EGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLSG-------- 121 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 F + +F +Y D + A+I A +V I C T Y A+KT Sbjct: 122 ------------FTHDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALKTA 168 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 ++ G + G GG S+ + A R++GID DK E ++GA + + Sbjct: 169 DLRIGQWVAISGAGGGLGSLAVQYAKALGLRVLGIDGGADKGEFVKSLGAEVFVDFTKTK 228 Query: 260 KPISEVLSEMTGN-----NVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSA 310 ++EV G NV + I + L G V+VG+P A Sbjct: 229 DVVAEVQKLTNGGPHGVINVSVSPHAINQSVQYVRTL-------GKVVLVGLPSGA 277 >2EER-A nrPDB Length = 347 Score = 81.6 bits (200), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 92/374 (24%), Positives = 157/374 (41%), Gaps = 40/374 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS---------K 73 +A L E +P +E+I + PK +V IKI A G+C +D H+ +G + K Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 PV +GHE G +E +G+ V GD V C CR + +LC G Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLC--DSPRWLG 119 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 + DG + V H+ + V +AAP + C T Y Sbjct: 120 INYDGA---YAEYVLVPHYKYLYKLRRLSAV---------EAAP------LTCSGVTTY- 160 Query: 194 AAVKTGKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 AV+ + P T VV G GG+G I K+ + IIG+D+ ++ E A GA Sbjct: 161 RAVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGADYV 220 Query: 253 ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKM 312 I+ S P+SE+ G + + + E + G V+VG+ A + Sbjct: 221 INA-SSQDPVSEIRRITQGKGADAVID-LNNSEKTLSIYPYVLAKQGKYVMVGL-FGADL 277 Query: 313 LTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 372 + P++ + G + G ++ D +++ LA+ + ++T + ++ +E + Sbjct: 278 KYHAPLITLNEVQFIGSLVG---NQSDFLGIMS--LAEAGKVKPMVTKTMKLEEANEAID 332 Query: 373 LLNSGQSI-RTVLT 385 L + +++ R VL Sbjct: 333 NLENFKAVGRQVLV 346 >4OH1-A nrPDB Length = 351 Score = 81.6 bits (200), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 84/360 (23%), Positives = 145/360 (40%), Gaps = 50/360 (13%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDHVIKG-------TMVSKFPVIVGHEATGIVESIG 90 E + PK +E+RIK++ IC +D H++ G T S P+ GHE +G+++ +G Sbjct: 25 EAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVIDKVG 84 Query: 91 EGVTTV--KPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKP 148 + K G KV+ + C C CR NLC + G +G Sbjct: 85 STAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLC-----SNMGYRMNG---------- 129 Query: 149 VHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCV 208 F+EY V S + I D A + L+ T ++ + K+ G + Sbjct: 130 ---------FSEYAVYHMSQIFPIPDDADLKDYALVEP--LTVALSSAEQAKISYGKSVA 178 Query: 209 VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSE 268 + G GG+G+ ++ + AGAS I D+ +K E A+ GA ++ + + ++E E Sbjct: 179 IMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EGVAERAIE 236 Query: 269 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML---LFTGRT 325 + G E G A A+ + G M DP+L L + Sbjct: 237 LAGGRYDCVLEGTG-------ATAAAKLGLQLLARDGDAVYFAMYGKDPILPVNLQSDLY 289 Query: 326 W-KGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384 W + + G ++ PK + + + D ++I + FE L S + + V+ Sbjct: 290 WDQKHIHGMIQGAWQFPKSIR--MIPRMDFSKIIQKEHTLTNYKQAFEDLYSKKYAKIVI 347 >1E3J-A nrPDB Length = 352 Score = 81.3 bits (199), Expect = 6e-16, Method: Compositional matrix adjust. Identities = 89/356 (25%), Positives = 159/356 (44%), Gaps = 36/356 (10%) Query: 24 AAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF----PVIVG 79 +AVL++Q +E+ + PK EV +++ GIC +D H + ++ F P+++G Sbjct: 7 SAVLYKQND-LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 HEA+G V +G+ V +K GD+V CR C C+ NLC D+T D Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLC--PDLTFCATPPD-- 121 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 G ++++ + F K+ D E+ L+ S G A + G Sbjct: 122 -----DGNLARYYVHAADFCH----------KLPDNVSLEEGALLE-PLSVGVHACRRAG 165 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGA--TECISP-K 256 V+ G+T +V G G +GL ++ K+ GA ++ + + E A GA T + P K Sbjct: 166 -VQLGTTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPAK 223 Query: 257 DSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYD 316 + I E + G+ T + G+ E I + GT ++VG+ ++M+T Sbjct: 224 EEESSIIERIRSAIGDLPNVTIDCSGN-EKCITIGINITRTGGTLMLVGM--GSQMVTV- 279 Query: 317 PMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 372 P++ R + + +D P + + + ++ QL+TH ++ + FE Sbjct: 280 PLVNACAREID--IKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFE 333 >3FSR-A nrPDB Length = 352 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 94/350 (26%), Positives = 148/350 (42%), Gaps = 41/350 (11%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E E P + ++ LA C +D H V +G + + +I+GHEA G V +G V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 KPGD+V+ P P R R + G+LA +F+ + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH--------SGGMLAG--WKFSN--------VKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F E+ V+++ ++A + P E +I +TG+ A + ++ GS+ VV G+G Sbjct: 118 GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVIGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 VGL I G K GA RIIG+ E A GAT+ ++ K+ + +V+ G Sbjct: 177 AVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNG-HIVDQVMKLTNGKG 235 Query: 274 VGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGC---- 329 V G ET+ A++ G+ + LL W GC Sbjct: 236 VDRVIMAGGGSETLSQAVSMVKPG-------GIISNINYHGSGDALLIPRVEW-GCGMAH 287 Query: 330 --VFGGL--KSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELL 374 + GGL R + +L+ K+ D +L+THV F I + F L+ Sbjct: 288 KTIKGGLCPGGRLRMERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >1YKF-A nrPDB Length = 352 Score = 76.6 bits (187), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 94/351 (26%), Positives = 155/351 (44%), Gaps = 43/351 (12%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E E P + ++ LA C +D H V +G + + +I+GHEA G V +G V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 KPGD+V+ P P R R + G+LA +F+ + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH--------SGGMLA--GWKFSN--------VKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F E+ V+++ ++A + P E +I +TG+ A + ++ G+T V G+G Sbjct: 118 GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVLGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI-SEVLSEMTGN 272 VGL + G K GA RII + + A GAT+ ++ KD PI S++++ G Sbjct: 177 PVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDG--PIESQIMNLTEGK 234 Query: 273 NVGYTFEVIGHLETMIDAL-------ASCHMNY-GTSVVVGVPPSAKMLTYDPMLLFTGR 324 V G+ + M A+ ++NY G V+ VP L + + + Sbjct: 235 GVDAAIIAGGNADIMATAVKIVKPGGTIANVNYFGEGEVLPVP----RLEWGCGMAH--K 288 Query: 325 TWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELL 374 T KG + G + R + +L+ K+ D +L+THV F I + F L+ Sbjct: 289 TIKGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >1KEV-A nrPDB Length = 351 Score = 76.3 bits (186), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 94/338 (27%), Positives = 148/338 (43%), Gaps = 43/338 (12%) Query: 51 IKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVI-PLFLP 108 ++ LA C +D H V +G + + +I+GHEA G V +G V KPGD+VI P P Sbjct: 29 VRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIVPCTTP 88 Query: 109 QCR--ECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDE 166 R E A N G+LA G +F + F EY V++ Sbjct: 89 DWRSLEVQAGFQQHSN----------GMLA---------GWKFSNFKD-GVFGEYFHVND 128 Query: 167 S--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCK 224 + ++A + P E +I +TG+ A + ++ GS+ VV G+G VGL I G K Sbjct: 129 ADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVVIGIGAVGLMGIAGAK 187 Query: 225 SAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHL 284 GA RIIG+ E A GAT+ ++ K+ + +V+ G V G Sbjct: 188 LRGAGRIIGVGSRPICVEAAKFYGATDILNYKNG-HIVDQVMKLTNGKGVDRVIMAGGGS 246 Query: 285 ETMIDALASC-------HMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSR 337 ET+ A++ ++NY S + P + +T KG + G + R Sbjct: 247 ETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCG-----MAHKTIKGGLCPGGRLR 301 Query: 338 DDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELL 374 ++ + + + + DL +L+THV F I E L+ Sbjct: 302 AEMLRDMVVY--NRVDLSKLVTHVYHGFDHIEEALLLM 337 >5VKT-A nrPDB Length = 362 Score = 75.9 bits (185), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 56/191 (29%), Positives = 80/191 (41%), Gaps = 22/191 (11%) Query: 22 CKAAVLWEQKQP---FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM-VSKFPVI 77 CK A W + S +V IK+L GIC TD HVIK + +PV+ Sbjct: 7 CKTAHGWAARDASGHLSPYSFSARIQGDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVV 66 Query: 78 VGHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLA 136 GHE G+V +G GVT K GD V + F+ CR C +C N C +T GV Sbjct: 67 PGHEVVGVVTDVGHGVTKFKAGDTVGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGV-- 124 Query: 137 DGTTRFTCKGKPVHHFMNTST---FTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 HH +T F++ VV + V ++ ++ P + + C T Y Sbjct: 125 ------------DHHHHGATTKGGFSDVLVVSQDFVVRVPESLPLDGAAPLLCAGVTVYS 172 Query: 194 AAVKTGKVKPG 204 + +PG Sbjct: 173 PMAQYALNEPG 183 >4EJ6-A nrPDB Length = 370 Score = 75.1 bits (183), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 82/309 (26%), Positives = 120/309 (38%), Gaps = 45/309 (14%) Query: 25 AVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATG 84 AV E S+ + + P ++ +K+ A GIC TD H++ G S PV +GHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 85 IVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 IV G V + PG ++ C C C+ NLC ++ G+ DG Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLC--RNLRAIGIHRDG------ 137 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDA--------APPEKVCLIGCGFSTGYGAAV 196 F EY +V +I P CL G S Sbjct: 138 ------------GFAEYVLVPRKQAFEIPLTLDPVHGAFCEPLACCLHGVDLS------- 178 Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK 256 +K GST + G G +GL + + AGA+ +I K A VGAT + P Sbjct: 179 ---GIKAGSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDP- 234 Query: 257 DSTKPISEVLSEMTG---NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 S + E ++ G V E G ET+ + GT V++GV P + + Sbjct: 235 -SAGDVVEAIAGPVGLVPGGVDVVIECAGVAETVKQSTRLAKAG-GTVVILGVLPQGEKV 292 Query: 314 TYDPM-LLF 321 +P +LF Sbjct: 293 EIEPFDILF 301 >4UEJ-A nrPDB Length = 346 Score = 74.3 bits (181), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 61/234 (26%), Positives = 98/234 (41%), Gaps = 35/234 (14%) Query: 48 EVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFL 107 EVR+KI ++G+C +D I +P+ +GHE +G ++++G GV + PGD V + L Sbjct: 27 EVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFSGYIDAVGSGVDDLHPGDAVACVPL 86 Query: 108 PQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDES 167 C C C + C + D G DG F EY VV Sbjct: 87 LPCFTCPECLKGFYSQCAKYDFIGS--RRDG------------------GFAEYIVVKRK 126 Query: 168 SV------AKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIM 221 +V I+D A E + + F G K ++ G G +GL I Sbjct: 127 NVFALPTDMPIEDGAFIEPITVGLHAFHLAQGCENK--------NVIIIGAGTIGLLAIQ 178 Query: 222 GCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP-ISEVLSEMTGNNV 274 + GA + ID++ +K A + GA + + + + P + VL E+ N + Sbjct: 179 CAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQMQSVLRELRFNQL 232 >3FPC-A nrPDB Length = 352 Score = 74.3 bits (181), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 89/350 (25%), Positives = 146/350 (41%), Gaps = 41/350 (11%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E E P + ++ LA C +D H V +G + + +I+GHEA G V +G V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 KPGD+V+ P P R R + G+LA +F+ + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH--------SGGMLA--GWKFSN--------VKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F E+ V+++ ++A + P E +I +TG+ A + +K G T V G+G Sbjct: 118 GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVIGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 VGL + G GA RI + K + A+ GAT+ I+ K+ + ++L G Sbjct: 177 PVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNGDI-VEQILKATDGKG 235 Query: 274 VGYTFEVIGHLETMIDALASC-------HMNY-GTSVVVGVPPSAKMLTYDPMLLFTGRT 325 V G + T A+ ++NY G + +P S + + G Sbjct: 236 VDKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNIDIPRSEWGVGMGHKHIHGGL- 294 Query: 326 WKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELL 374 C G L+ + +L+ K+ D +L+THV F I + F L+ Sbjct: 295 ---CPGGRLR----MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLM 337 >3FPL-A nrPDB Length = 351 Score = 73.6 bits (179), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 95/340 (27%), Positives = 152/340 (44%), Gaps = 47/340 (13%) Query: 51 IKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVI-PLFLP 108 ++ LA C +D H V +G + + +I+GHEA G V +G V KPGD+VI P P Sbjct: 29 VRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSEVKDFKPGDRVIVPCTTP 88 Query: 109 QCR--ECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDE 166 R E A N G+LA G +F + F EY V++ Sbjct: 89 DWRSLEVQAGFQQHSN----------GMLA---------GWKFSNFKD-GVFGEYFHVND 128 Query: 167 S--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCK 224 + ++A + P E +I +TG+ A + ++ G+T V G+G VGL + G K Sbjct: 129 ADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAVLGIGPVGLMAVAGAK 187 Query: 225 SAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI-SEVLSEMTGNNVGYTFEVIGH 283 GA RII + + A GAT+ ++ KD PI S++++ G V G+ Sbjct: 188 LRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDG--PIESQIMNLTEGKGVDAAIIAGGN 245 Query: 284 LETMIDAL-------ASCHMNY-GTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLK 335 + M A+ ++NY G V+ VP L + + +T KG + G + Sbjct: 246 ADIMATAVKIVKPGGTIANVNYFGEGEVLPVP----RLEWGCGMAH--KTIKGGLCPGGR 299 Query: 336 SRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELL 374 R ++ + + + + DL +L+THV F I E L+ Sbjct: 300 LRAEMLRDMVVY--NRVDLSKLVTHVYHGFDHIEEALLLM 337 >5Z0C-A nrPDB Length = 374 Score = 69.3 bits (168), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 87/317 (27%), Positives = 132/317 (41%), Gaps = 49/317 (15%) Query: 48 EVRIKILATGICRTDDHVIKGTMVSK-FPVIVGHEATGIVESIGEGVTTVKPGDKV-IPL 105 +V K+L GIC +D H IK + +P + GHE G V +G V K GDKV + Sbjct: 40 DVTFKVLYCGICHSDLHYIKNEWSNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGC 99 Query: 106 FLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVD 165 + C C C N N C +T DGT +N +++ VV Sbjct: 100 IVGSCHSCPNCNNHLENYCPNRILTFGSRYYDGT-------------LNHGGYSDLMVVQ 146 Query: 166 ESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKS 225 E +I DA P + + C T Y G KPG V GLGG+G + K+ Sbjct: 147 EHFAVRIPDALPLDSAAPLLCAGITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKA 206 Query: 226 AGASRIIGIDLNKDKFEKAMA-VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHL 284 G ++ + + K E A++ +GA I D+ + + V G + Sbjct: 207 FGV-KVTVVSTSPAKKEDAISGLGAHSFILSTDAEQMQAAV----------------GTM 249 Query: 285 ETMIDALASCH---------MNYGTSVVVGVPPSAKMLTYDPMLLFTGRTW-KGCVFGGL 334 + +ID +++ H ++G V+VG PP L P+LL GR G GG+ Sbjct: 250 DGIIDTVSASHPLPPLISLLKSHGKLVMVGDPPKPLELPVFPLLL--GRKMVAGSAIGGM 307 Query: 335 KSRDDVPKLVTEFLAKK 351 K + + +F AK+ Sbjct: 308 KETQE----MIDFAAKE 320 >5K1S-A nrPDB Length = 362 Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 78/303 (25%), Positives = 126/303 (41%), Gaps = 28/303 (9%) Query: 23 KAAVL--WEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM-VSKFPVIVG 79 KA VL + + +E + + P EV +++ A G+C D +G + + P I+G Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 HEA G V +G K GD+ L C +C CR+ +LC ++D Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLC-KTD----------- 126 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 RF + P + ++ V + ++ + P + + C T G Sbjct: 127 NRFFGEELP-------GGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRG 179 Query: 200 KVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 KV+ G T ++ G GGVGLS + + GA R+I + ++ K + GA E I + Sbjct: 180 KVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSR-G 237 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 S+V G V E++G T L S M G VVV + M+ +P Sbjct: 238 LDFASDVRKRTQGAGVDVAVEIVGS-ATFDQTLKS--MAPGGRVVVVGNLESGMVQLNPG 294 Query: 319 LLF 321 L+ Sbjct: 295 LVI 297 >4JLW-A nrPDB Length = 399 Score = 66.2 bits (160), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 76/281 (27%), Positives = 124/281 (44%), Gaps = 30/281 (10%) Query: 33 PFSIEEIEVAPPKTKE---------VRIKILATGICRTDDHVIKGTMVSKFPVIVGHEAT 83 P +E + PK ++ V +++++T IC +D H+++G + +++GHE T Sbjct: 12 PGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEIT 71 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRF- 142 G V IG GV T+K GD V F C C C+ +C+ + R A G Sbjct: 72 GEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVCLTVN-PARAGGAYGYVDMG 130 Query: 143 -TCKGKPVHHFMNTSTFTEYTVVD-ESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGK 200 G+ + + + F + + E+++ KI D CL TGY AV G Sbjct: 131 GWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDL-----TCLSDI-LPTGYHGAVTAG- 183 Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 V PGST + G G VGL+ + GA+ +I D+N + A G KD+ Sbjct: 184 VGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLSKDT-- 241 Query: 261 PISEVLSEMTG--------NNVGYTFEVIGHLETMIDALAS 293 P+ E ++ + G + VG+ GH + +A A+ Sbjct: 242 PLHEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPAT 282 >1YQX-A nrPDB Length = 366 Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 77/307 (25%), Positives = 127/307 (41%), Gaps = 45/307 (14%) Query: 47 KEVRIKILATGICRTDDHVIKGTM-VSKFPVIVGHEATGIVESIGEGVTTVKPGDKV-IP 104 ++VR K+L G+C +D H IK S +P++ GHE G V +G V V GDKV + Sbjct: 42 EDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGEVTEVGSKVKKVNVGDKVGVG 101 Query: 105 LFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVV 164 + C C +C N N C + +T + DGT + ++ + V Sbjct: 102 CLVGACHSCESCANDLENYCPKMILTYASIYHDGTITY-------------GGYSNHMVA 148 Query: 165 DESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCK 224 +E + + D P + + C T Y G +PG + GLGG+G + K Sbjct: 149 NERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPGKHIGIVGLGGLGHVAVKFAK 208 Query: 225 SAGASRIIGIDLNKDKFEKAMA-VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGH 283 + G S++ I + K E+A+ GA + +D + + G Sbjct: 209 AFG-SKVTVISTSPSKKEEALKNFGADSFLVSRDQEQMQAAA----------------GT 251 Query: 284 LETMIDALASCH---------MNYGTSVVVGVPPSAKMLTYDPMLLFTGRTW-KGCVFGG 333 L+ +ID +++ H ++G ++VG P K L L GR G GG Sbjct: 252 LDGIIDTVSAVHPLLPLFGLLKSHGKLILVGAP--EKPLELPAFSLIAGRKIVAGSGIGG 309 Query: 334 LKSRDDV 340 +K ++ Sbjct: 310 MKETQEM 316 >2OUI-A nrPDB Length = 360 Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 85/339 (25%), Positives = 139/339 (41%), Gaps = 41/339 (12%) Query: 51 IKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVI-PLFLP 108 ++ LA C +D H V G + + +I+GHEA G + +G V +K GDKVI P P Sbjct: 29 VRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRLKVGDKVIVPAITP 88 Query: 109 QCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDES- 167 E + R + G+L G +F+ F+E V+E+ Sbjct: 89 DWGEEESQRG--------YPMHSGGML--GGWKFSN--------FKDGVFSEVFHVNEAD 130 Query: 168 -SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSA 226 ++A + PE ++ +TG+ A + +K G T V G+G VGL + G Sbjct: 131 ANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDTVCVIGIGPVGLMSVAGANHL 189 Query: 227 GASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLET 286 GA RI + K + A+ GAT+ I+ K+ + ++L G V G + T Sbjct: 190 GAGRIFAVGSRKHCCDIALEYGATDIINYKNG-DIVEQILKATDGKGVDKVVIAGGDVHT 248 Query: 287 MIDALASC-------HMNY-GTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRD 338 A+ ++NY G + +P S + + G T G R Sbjct: 249 FAQAVKMIKPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIHGGLTPGG--------RV 300 Query: 339 DVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNS 376 + KL + K D +LITH +K+ + L+ + Sbjct: 301 RMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKN 339 >1R37-A nrPDB Length = 347 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 89/374 (23%), Positives = 156/374 (41%), Gaps = 42/374 (11%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS---------K 73 +A L E +P S++EI V PK +V IK+ A G+C +D H+ +G + K Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 PV +GHE G +E +G+ V GD V C CR + +LC G Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLC--DSPRWLG 119 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDE-SSVAKIDDAAPPEKVCLIGCGFSTGY 192 + DG + EY +V + K+ E L G +T Sbjct: 120 INFDG------------------AYAEYVIVPHYKYMYKLRRLNAVEAAPLTCSGITT-- 159 Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSV-IMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 AV+ + P T +V G GG ++ + K+ + IIG+D+ ++ E A GA Sbjct: 160 YRAVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADY 219 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 I+ P++E+ V + + + E + G V+VG+ A Sbjct: 220 VIN-ASMQDPLAEIRRITESKGVDAVID-LNNSEKTLSVYPKALAKQGKYVMVGL-FGAD 276 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 + + P++ + + G + G ++ D ++ LA+ + +IT + ++ +E Sbjct: 277 LHYHAPLITLSEIQFVGSLVG---NQSDFLGIMR--LAEAGKVKPMITKTMKLEEANEAI 331 Query: 372 ELLNSGQSI-RTVL 384 + L + ++I R VL Sbjct: 332 DNLENFKAIGRQVL 345 >1UUF-A nrPDB Length = 369 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 78/336 (23%), Positives = 135/336 (40%), Gaps = 34/336 (10%) Query: 20 IKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIV 78 +K KA + KQP +I P +V+I+I G+C +D H ++ + +P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 79 GHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 GHE G V ++G+ V PGD V + + C+ C C + N C Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDH---------MT 131 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIG---CGFSTGYGA 194 GT +P H +++ VV E V +I P E++ + C T Y + Sbjct: 132 GTYNSPTPDEPGH---TLGGYSQQIVVHERYVLRIRH--PQEQLAAVAPLLCAGITTY-S 185 Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGA--SRIIGIDLNKDKFEKAMAVGATEC 252 ++ + PG V G+G MG K A A + ++ ++ K E A A+GA E Sbjct: 186 PLRHWQAGPGKKVGVV---GIGGLGHMGIKLAHAMGAHVVAFTTSEAKREAAKALGADEV 242 Query: 253 ISPKDSTKPISEVLS-EMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 ++ +++ + + + S + N V +D + GT +VG P + Sbjct: 243 VNSRNADEMAAHLKSFDFILNTVAAPHN--------LDDFTTLLKRDGTMTLVGAPATPH 294 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEF 347 L+ R G + GG+ ++ E Sbjct: 295 KSPEVFNLIMKRRAIAGSMIGGIPETQEMLDFCAEH 330 >1KOL-A nrPDB Length = 398 Score = 62.4 bits (150), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 69/246 (28%), Positives = 110/246 (44%), Gaps = 23/246 (9%) Query: 36 IEEIEVAPPKTKEVR----IKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGE 91 I+ ++ P+ K++ +K+++T IC +D H+++G ++ +++GHE TG V G Sbjct: 19 IDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKGR 78 Query: 92 GVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHH 151 V ++ GD V F C C +C+ +C +T A G + G Sbjct: 79 DVENLQIGDLVSVPFNVACGRCRSCKEMHTGVC----LTVNPARAGGAYGYVDMGD---- 130 Query: 152 FMNTSTFTEYTVV---DESSVAKIDDAAPPEKVCLIGCG---FSTGYGAAVKTGKVKPGS 205 T EY +V D + + D EK+ + C TGY AV G V PGS Sbjct: 131 --WTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAVTAG-VGPGS 187 Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEV 265 T V G G VGL+ + GA+ +I DLN + A A G I+ P+ E Sbjct: 188 TVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFE--IADLSLDTPLHEQ 245 Query: 266 LSEMTG 271 ++ + G Sbjct: 246 IAALLG 251 >3UOG-A nrPDB Length = 363 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 95/230 (41%), Gaps = 28/230 (12%) Query: 29 EQKQPFSIEEIEVAPPKTKE--VRIKILATGICRTDDHVIKGTM--VSKFPVIVGHEATG 84 E P ++ E P+ E + ++ LA + D V++ M FP + + +G Sbjct: 34 ETVAPHDLKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSG 93 Query: 85 IVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 +VE++G+ VT +PGD+VI F P + R G + G Sbjct: 94 VVEAVGKSVTRFRPGDRVISTFAPGW--LDGLRPGTGRTPAYETLGG------------- 138 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPG 204 + +EY V+ E + + + C T + A V+ G ++ G Sbjct: 139 --------AHPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAG 190 Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 VV G GGV L + K+ GA I+ +++K ++A A+GA I+ Sbjct: 191 DRVVVQGTGGVALFGLQIAKATGAEVIV-TSSSREKLDRAFALGADHGIN 239 >3IP1-A nrPDB Length = 404 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 82/366 (22%), Positives = 144/366 (39%), Gaps = 54/366 (14%) Query: 45 KTKEVRIKILATGICRTDDHVIKGTM--------VSKFPVIVGHEATGIVESIGEGVTTV 96 K E+ IK+ A GIC +D H+ + ++ FPV +GHE +G+V G Sbjct: 54 KPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVTLGHEFSGVVVEAGPEAINR 113 Query: 97 KP------GDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVH 150 + G+ V + C C C N C ++ G DG Sbjct: 114 RTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHC--ENLNELGFNVDGA----------- 160 Query: 151 HFMNTSTFTEYTVVDES---SVAKIDDAAPPEKVCLIGCGF---STGYGAA-VKTGKVKP 203 F EY VD S+ +++ +++ L G S Y A V+ G ++P Sbjct: 161 -------FAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLVEPTSVAYNAVIVRGGGIRP 213 Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G V+ G G +GL+ + K AGAS++I + ++ + A +GA I P + Sbjct: 214 GDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENF-VE 272 Query: 264 EVLSEMTGNNVGYTFEVIGHLETMIDALASC-HMNYGTSVVVGVPPSAKMLTYDPMLLFT 322 VL G E G + + + G + V + A D + T Sbjct: 273 AVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINATVAIVARA-----DAKIPLT 327 Query: 323 GRTW---KGCVFG--GLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG 377 G + + + G G P++++ +A D+ ++I+ + ++I E + L + Sbjct: 328 GEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTVSMEEIPEYIKRLQTD 386 Query: 378 QSIRTV 383 +S+ V Sbjct: 387 KSLVKV 392 >3M6I-A nrPDB Length = 363 Score = 59.7 bits (143), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 86/368 (23%), Positives = 143/368 (38%), Gaps = 64/368 (17%) Query: 27 LWEQKQPFSIEEIEVAPP-KTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHE 81 LW + S+E ++ K EV + + +TGIC +D H K G M+ + ++GHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 82 ATGIVESIGEGVTTVKPGDKVIPLFLPQ--CRECNACRNPDGNLCIRSDITGRGVLADGT 139 + G V ++ V ++K GD+V PQ C C C N C R D + Sbjct: 80 SAGEVIAVHPSVKSIKVGDRV--AIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLL 137 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 R+ H + ++ +++ SVA A ++ Sbjct: 138 RRYVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQRA 175 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV------GATECI 253 V+ G ++ G G +GL ++ K+AGA ++ D+++ + + A + E + Sbjct: 176 GVRLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEICPEVVTHKVERL 235 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVP------ 307 S ++S K I E G E G +E+ I A G V+GV Sbjct: 236 SAEESAKKIVESFG---GIEPAVALECTG-VESSIAAAIWAVKFGGKVFVIGVGKNEIQI 291 Query: 308 PSAKMLTYDPMLLFTGR---TWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPF 364 P + + L F R TW + +LV L DL +L+TH P Sbjct: 292 PFMRASVREVDLQFQYRYCNTWPRAI-----------RLVENGL---VDLTRLVTHRFPL 337 Query: 365 KKISEGFE 372 + + FE Sbjct: 338 EDALKAFE 345 >4OAQ-A nrPDB Length = 367 Score = 58.9 bits (141), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 72/346 (20%), Positives = 136/346 (39%), Gaps = 43/346 (12%) Query: 28 WEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM--VSKFPVIVGHEATGI 85 W + + S E ++ P +V +K G+C +D H + + + ++VGHE G Sbjct: 20 WNRPKLASYERKQINP---HDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 86 VESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 V ++G+ VT K GD+V I CR C C + + C + G + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ-----------GAATYNS 125 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPG 204 K ++++ ++ +++ DE V I + P + C T + ++ + Sbjct: 126 KDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDAR 185 Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 V G + + +A + + + K E+AM +GA + ++ + Sbjct: 186 GKNVGIIGIGGLGHLALQFANAMGANVTAFSRSSSKKEQAMKLGAHDFVATGE------- 238 Query: 265 VLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTS-------VVVGVPPSAKMLTYDP 317 + N F+ I + + ID L Y ++ V VG+PPS P Sbjct: 239 --DKTWYKNYDDHFDFILNCASGIDGLNLSE--YLSTLKVDKKFVSVGLPPSEDKFEVSP 294 Query: 318 MLLFTGRTWKGCVFGG--LKSRDDVPKLVTEFLAKKFDLDQLITHV 361 +G FG L S+ +V +++ LA K ++ +I V Sbjct: 295 FTFLQ----QGASFGSSLLGSKTEVKEMLN--LAAKHNVRPMIEEV 334 >5H82-A nrPDB Length = 389 Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 83/341 (24%), Positives = 139/341 (40%), Gaps = 32/341 (9%) Query: 48 EVRIKILATGICRTDDHVIKGTM-VSKFPVIVGHEATGIVESIGEGVTTVKPGDKV-IPL 105 +V+ K+L G+C D K T +K+P + GHE GIV IG V K GDKV + Sbjct: 55 DVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVGVGN 114 Query: 106 FLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMN-------TSTF 158 F+ C +C C C + + DGT F+ + V+ ++ + Sbjct: 115 FIGSCGKCERCNEGLEPYCPKV------IYTDGTA-FSDENNTVYGDVSGDGEDRIYGGY 167 Query: 159 TEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLS 218 + V +E V + + P I CG Y G KPG + V G G +G Sbjct: 168 SNIMVANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKL 227 Query: 219 VIMGCKSAGAS-RIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYT 277 + K+ GA+ +I ++K K E G + K+ P +E T + + Sbjct: 228 AVKFAKAFGANVTVISTSISK-KQEAIEKYGVDRFLISKE---PEEMKAAESTLDGI--- 280 Query: 278 FEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSR 337 F+ + + + L GT V++GV A L P+L+ R + G + G +K Sbjct: 281 FDCVPSVHPLHPLLNLLKFE-GTFVMLGVAVEAYELPVSPLLM-GRRKFVGSISGTMKET 338 Query: 338 DDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 378 + + +F AK + + ++P ++ E + G Sbjct: 339 QE----MLDFAAKHNIVSDI--ELIPMDYVNTALERIAKGN 373 >1Q1N-A nrPDB Length = 360 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 89/354 (25%), Positives = 142/354 (40%), Gaps = 42/354 (11%) Query: 43 PPKTKEVRIKILATGICRTDDHVIKGTMVS-KFPVIVGHEATGIVESIG-EGVTTVKPGD 100 P ++ IKI A G+C +D H G + K P++VGHE G V +G + + +K G Sbjct: 30 PFYDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKVVKLGPKSNSGLKVGQ 89 Query: 101 KV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFT 159 +V + + C EC+ C+N + C + T DG +++ + Sbjct: 90 RVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDG-------------YVSQGGYA 136 Query: 160 EYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSV 219 Y V E V I + P + CG T Y V+ G PG + GLGG+G Sbjct: 137 NYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNG-CGPGKKVGIVGLGGIGSMG 195 Query: 220 IMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFE 279 + K+ GA + I + K E AM +GA I+ + G TF+ Sbjct: 196 TLISKAMGAETYV-ISRSSRKREDAMKMGADHYIATLEEGD---------WGEKYFDTFD 245 Query: 280 VI----GHLETMIDALASCHMNYGTSVV-VGVPPSAKMLTYDPMLLFTGRTWKGCVFGGL 334 +I L + + M G +V + +P +ML+ P L + G + Sbjct: 246 LIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYGL-KAVSISYSALGSI 304 Query: 335 KSRDDVPKLVTEFLAKKFDLDQLITHVLPFKK--ISEGFELLNSGQSIRTVLTF 386 K + + KLV+E K + LP + + E FE + G +R T Sbjct: 305 KELNQLLKLVSEKDIK------IWVETLPVGEAGVHEAFERMEKGD-VRYRFTL 351 >2DPH-A nrPDB Length = 398 Score = 54.7 bits (130), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 63/235 (26%), Positives = 100/235 (42%), Gaps = 30/235 (12%) Query: 49 VRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLP 108 V +K+++T IC +D H+ +G + ++GHE TG V G V + GD V F Sbjct: 35 VILKVVSTNICGSDQHIYRGRFIVPKGHVLGHEITGEVVEKGSDVELMDIGDLVSVPFNV 94 Query: 109 QCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVV---- 164 C C C+ ++C + + L G F KG + EY +V Sbjct: 95 ACGRCRNCKEARSDVCENNLVNPDADL--GAFGFDLKGW-------SGGQAEYVLVPYAD 145 Query: 165 --------DESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVG 216 E ++ KI D + LI TG+ V G VKPGS + G G VG Sbjct: 146 YMLLKFGDKEQAMEKIKD------LTLISDILPTGFHGCVSAG-VKPGSHVYIAGAGPVG 198 Query: 217 LSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 G + GA+ +I D N ++ K ++ E I ++S P+ + + ++ G Sbjct: 199 RCAAAGARLLGAACVIVGDQNPERL-KLLSDAGFETIDLRNSA-PLRDQIDQILG 251 >3WLE-A nrPDB Length = 341 Score = 54.3 bits (129), Expect = 9e-08, Method: Compositional matrix adjust. Identities = 28/88 (31%), Positives = 45/88 (51%) Query: 37 EEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 ++ V PK ++ +K+ A G+C +D HVI + ++GHE G V ++G+ V Sbjct: 27 NDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGTVAAVGDDVINY 86 Query: 97 KPGDKVIPLFLPQCRECNACRNPDGNLC 124 K GD+V + C C CR N+C Sbjct: 87 KVGDRVACVGPNGCGGCKYCRGAIDNVC 114 >5H83-A nrPDB Length = 360 Score = 50.8 bits (120), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 29/86 (33%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Query: 47 KEVRIKILATGICRTDDHVIKGTM-VSKFPVIVGHEATGIVESIGEGVTTVKPGDKV-IP 104 +V+ K+L G C D + ++K+P ++GHE G+V IG V K GDKV + Sbjct: 40 NDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSKVQKFKVGDKVGVG 99 Query: 105 LFLPQCRECNACRNPDGNLCIRSDIT 130 F+ C +C C N N C + + T Sbjct: 100 GFVGACEKCEMCVNGVENNCSKVEST 125 >2VCY-A nrPDB Length = 344 Score = 50.1 bits (118), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 25/71 (35%), Positives = 45/71 (63%), Gaps = 2/71 (2%) Query: 36 IEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFPVIVGHEATGIVESIGEGV 93 ++ +E+A + +VR+K+LA I +D ++I+G ++ + P + G+E V ++G V Sbjct: 31 LKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELPAVGGNEGVAQVVAVGSNV 90 Query: 94 TTVKPGDKVIP 104 T +KPGD VIP Sbjct: 91 TGLKPGDWVIP 101 >5FI5-A nrPDB Length = 357 Score = 48.9 bits (115), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 26/79 (32%), Positives = 40/79 (50%), Gaps = 2/79 (2%) Query: 48 EVRIKILATGICRTDDHVIKGTM-VSKFPVIVGHEATGIVESIGEGVTTVKPGDKV-IPL 105 +V++K+L G C+ D + K + +P ++GHE G V +G V K GDKV + Sbjct: 44 DVQLKVLYCGTCQYDREMSKNKFGFTSYPYVLGHEIVGEVTEVGSKVQKFKVGDKVGVAS 103 Query: 106 FLPQCRECNACRNPDGNLC 124 + C +C C N N C Sbjct: 104 IIETCGKCEMCTNEVENYC 122 >6DKH-A nrPDB Length = 346 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 74/341 (21%), Positives = 133/341 (39%), Gaps = 34/341 (9%) Query: 51 IKILATGICRTDDHVIK----GTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLF 106 ++I GIC +D H + G + K P+++GHE G V I + + G V Sbjct: 35 VQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAINP 92 Query: 107 LPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDE 166 C C C + N C +D+ RF G ++ FT Y +V+ Sbjct: 93 SKPCGHCKYCIEHNENQC--TDM-----------RFF--GSAMYFPHVDGGFTRYKMVET 137 Query: 167 SSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSA 226 S A EKV + AA + G+++ G + G+G +G ++ K+ Sbjct: 138 SQCVPYP-AKADEKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVKTL 195 Query: 227 GASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLET 286 GA+ I+ D++ +GA ++P++ + +E +V +FEV GH + Sbjct: 196 GAAEIVCADVSPRSLSLGKEMGADVLVNPQNDD--MDHWKAEKGYFDV--SFEVSGHPSS 251 Query: 287 MIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTE 346 + L + V+V V M + PM+ G+ + G + + V+ Sbjct: 252 VNTCL---EVTRARGVMVQVGMGGAMAEF-PMMTLIGKEIS--LRGSFRFTSEFNTAVSW 305 Query: 347 FLAKKFDLDQLITHVLPFKKISEGFELL-NSGQSIRTVLTF 386 + L++ PF + E + Q+ + L F Sbjct: 306 LANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >1YB5-A nrPDB Length = 351 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 49/223 (21%), Positives = 90/223 (40%), Gaps = 50/223 (22%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGHEATGIVESIGEGVTT 95 +I V PK +V IK+ A G+ + ++ GT K P G + G++E++G+ + Sbjct: 49 DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 108 Query: 96 VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 K GD+V S I+G Sbjct: 109 FKKGDRVFT---------------------SSTISG------------------------ 123 Query: 156 STFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGL-GG 214 + EY + + +V K+ + ++ IG + T Y A + + VK G + +V G GG Sbjct: 124 -GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASGG 182 Query: 215 VGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 VGL+ ++ G +I+G ++ + + GA E + ++ Sbjct: 183 VGLAACQIARAYGL-KILGTAGTEEGQKIVLQNGAHEVFNHRE 224 >1WLY-A nrPDB Length = 333 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 29/85 (34%), Positives = 47/85 (55%), Gaps = 6/85 (7%) Query: 24 AAVLWEQKQP--FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT----MVSKFPVI 77 AAV+ ++ P F EE++V P +VR++ A G+ D + G +V + P++ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPIV 63 Query: 78 VGHEATGIVESIGEGVTTVKPGDKV 102 VG EA +VE +G GVT G++V Sbjct: 64 VGFEAAAVVEEVGPGVTDFTVGERV 88 >6C49-A nrPDB Length = 350 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 86/363 (23%), Positives = 145/363 (39%), Gaps = 49/363 (13%) Query: 29 EQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-FPVIVGHEATGIVE 87 E+ P+ + E+ P +V +K+ G+C +D V+ S +PV+ GHE G + Sbjct: 24 EKLVPYKFDAGELQP---HQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAGHEIIGRIV 80 Query: 88 SIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKG 146 ++G ++ G +V I C+ C+ C I G+ VL G T G Sbjct: 81 ALGSEAKGLQIGQRVGIGWTAESCQACDEC------------IGGQQVLCTGENIATIVG 128 Query: 147 KPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGST 206 + F + + + PE + CG T + +K K++ Sbjct: 129 -------HAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLKH-KIQATHH 180 Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVL 266 V G+GG+G I K+ G I N DK E+ A+GA ++ +D +E + Sbjct: 181 VGVIGIGGLGHIAIKLLKAWGC-EITAFSSNPDKTEELKAMGADHVVNSRD-----TEAV 234 Query: 267 SEMTG--NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGR 324 G + + T V + I LA G+ +G LT +P+ + G Sbjct: 235 KAQKGKFDLLLSTVNVTLNWRAFISTLAP----NGSLHFLG-------LTLEPVPVSVGS 283 Query: 325 TWKGC--VFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQS-IR 381 G V G + + +F A+K Q+ + P +++E E L+SGQ+ R Sbjct: 284 LIDGAKSVTGSPTGSPAALRQLLKFAARKKIAPQI--ELFPMSQLNEAIERLHSGQARYR 341 Query: 382 TVL 384 VL Sbjct: 342 IVL 344 >2CDC-A nrPDB Length = 366 Score = 42.0 bits (97), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 12/77 (15%) Query: 48 EVRIKILATGICRTDDHVIKGTM-VSKFP-----VIVGHEATGIVESIGEGVTTVKPGDK 101 +++I+ + GIC D ++ G + +S P +++GHEA G+VE G + GD Sbjct: 28 KIKIRTIYNGICGADREIVNGKLTLSTLPKGKDFLVLGHEAIGVVEESYHGFSQ---GDL 84 Query: 102 VIPLFLPQCRECNACRN 118 V+P+ R C CRN Sbjct: 85 VMPV---NRRGCGICRN 98 >3JYN-A nrPDB Length = 325 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 60/240 (25%), Positives = 98/240 (40%), Gaps = 55/240 (22%) Query: 33 PFSIEEIEVAP--PKTKEVRIKILATGICRTDDHVIKGTMVSKF-PVIVGHEATGIVESI 89 P +E ++ P P + V ++ A G+ D + G + F P +G E G+VE++ Sbjct: 13 PEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVEAV 72 Query: 90 GEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPV 149 G+ VT K GD+V G G L Sbjct: 73 GDEVTRFKVGDRV--------------------------AYGTGPLG------------- 93 Query: 150 HHFMNTSTFTEYTVVDESSVAKIDDAAPPEK-VCLIGCGFSTGYGAAVKTGKVKPGSTCV 208 ++E V+ E+++ K+ D+ E+ L+ G + Y +T +VKPG + Sbjct: 94 -------AYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQY-LLRQTYQVKPGEIIL 145 Query: 209 VF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPISEV 265 GGVG K+ GA ++IG + +K A A+GA E I S +D K + E+ Sbjct: 146 FHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDYSHEDVAKRVLEL 204 >3FBG-A nrPDB Length = 346 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/93 (30%), Positives = 44/93 (47%), Gaps = 9/93 (9%) Query: 31 KQPFSIEE--------IEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEA 82 +QPF + + +++ PK E+ +KI + + D + VSK P ++G +A Sbjct: 9 EQPFKLSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQ-RLMDVSKAPRVLGFDA 67 Query: 83 TGIVESIGEGVTTVKPGDKVIPLFLPQCRECNA 115 G+VES+G VT GD V P NA Sbjct: 68 IGVVESVGNEVTMFNQGDIVYYSGSPDQNGSNA 100 >3QWB-A nrPDB Length = 334 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 57/251 (22%), Positives = 94/251 (37%), Gaps = 55/251 (21%) Query: 37 EEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E+ V +E+ IK TG+ + + KG + P ++G EA+G V + G+GVT Sbjct: 26 EDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGVTNF 85 Query: 97 KPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTS 156 + GD+V +++ S Sbjct: 86 EVGDQV------------------------------------------------AYISNS 97 Query: 157 TFTEYT-VVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGK---VKPGSTCVVF-G 211 TF +Y+ + + V K+ E++ L G A T + VK G ++F Sbjct: 98 TFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLLFAA 157 Query: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 GGVGL + K GA I + +K + A GA I+ + +VL G Sbjct: 158 AGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINA-SKEDILRQVLKFTNG 215 Query: 272 NNVGYTFEVIG 282 V +F+ +G Sbjct: 216 KGVDASFDSVG 226 >1QOR-A nrPDB Length = 327 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/74 (32%), Positives = 38/74 (51%), Gaps = 3/74 (4%) Query: 33 PFSIEEIEVAP--PKTKEVRIKILATGICRTDDHVIKGTMVS-KFPVIVGHEATGIVESI 89 P ++ +E P P E++++ A GI D ++ G P +G EA GIV + Sbjct: 13 PEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAAGIVSKV 72 Query: 90 GEGVTTVKPGDKVI 103 G GV +K GD+V+ Sbjct: 73 GSGVKHIKAGDRVV 86 >5A3V-A nrPDB Length = 329 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 25/73 (34%), Positives = 37/73 (50%), Gaps = 4/73 (5%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDHVIKGT----MVSKFPVIVGHEATGIVESIGEGV 93 ++ V PK+ EV +K+ AT + D + KG + KFP I + G V +G GV Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGV 84 Query: 94 TTVKPGDKVIPLF 106 K GDKV+ + Sbjct: 85 KNFKAGDKVVAVL 97 >4A27-A nrPDB Length = 349 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 39/62 (62%), Gaps = 2/62 (3%) Query: 44 PKTKEVRIKILATGICRTDDHVIKGTMVS--KFPVIVGHEATGIVESIGEGVTTVKPGDK 101 P+ E++I++ A G+ D V +G + + K P++ G E +GIVE++G+ V + GD+ Sbjct: 28 PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 87 Query: 102 VI 103 V+ Sbjct: 88 VM 89 >3SLK-A nrPDB Length = 795 Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust. Identities = 47/209 (22%), Positives = 72/209 (34%), Gaps = 57/209 (27%) Query: 37 EEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVI--VGHEATGIVESIGEGVT 94 E AP EVRI + A G+ D + G +P + +G E G+V G GVT Sbjct: 229 EPTATAPLGDGEVRIAMRAAGVNFRDALIALGM----YPGVASLGSEGAGVVVETGPGVT 284 Query: 95 TVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMN 154 + PGD+V+ M Sbjct: 285 GLAPGDRVM------------------------------------------------GMI 296 Query: 155 TSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVF-GLG 213 F V D V +I + + F T Y A V ++PG + +V G Sbjct: 297 PKAFGPLAVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSAAG 356 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFE 242 GVG++ I + GA + ++DK++ Sbjct: 357 GVGMAAIQLARHLGAE--VYATASEDKWQ 383 >4Y1B-A nrPDB Length = 425 Score = 37.0 bits (84), Expect = 0.013, Method: Compositional matrix adjust. Identities = 55/240 (22%), Positives = 98/240 (40%), Gaps = 38/240 (15%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPV-----------IVGHEA 82 F E ++V P +V +K++A G+ + G + I G + Sbjct: 58 FRTEVVDVPPVGPGQVLVKVMAAGVNYNNVWAALGEPLDVIAARQKQGATEDFHIGGSDL 117 Query: 83 TGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRF 142 +GIV ++G+GV +KPG +V+ L ACR + IR + AD T Sbjct: 118 SGIVWAVGDGV-RLKPGAEVVVL---------ACRWDESAQDIR-------LGADPVTSS 160 Query: 143 TCKGKPVHHFMNTSTFTEYTVVDE----SSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 T + N +F ++ VVDE ++ AA + + +G T Sbjct: 161 TQRVWGYEE--NYGSFAQFAVVDEYMCHPKPQRLSWAAASCYMATAATAYRQLFGWEPHT 218 Query: 199 GKVKPGSTCVVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 V+PG +++ G GG+G I + G + + ++++ E M +GA I ++ Sbjct: 219 --VRPGDPVLIWGGAGGLGSIAIQLVRHVGGIPVAVVS-SEERGEFCMRLGAKGWIDRRE 275 >4RVS-A nrPDB Length = 329 Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust. Identities = 21/64 (32%), Positives = 32/64 (50%), Gaps = 4/64 (6%) Query: 44 PKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGV----TTVKPG 99 P E+ IK A G+ D + G + P ++G E G VE++G GV T + G Sbjct: 26 PGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTVEAVGPGVTAADTAISVG 85 Query: 100 DKVI 103 D+V+ Sbjct: 86 DRVV 89 >4J6F-A nrPDB Length = 382 Score = 34.7 bits (78), Expect = 0.068, Method: Compositional matrix adjust. Identities = 47/210 (22%), Positives = 80/210 (38%), Gaps = 47/210 (22%) Query: 37 EEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-----------------FPVIVG 79 ++ V P EV IK+ A G+ TD V +G ++ FP I G Sbjct: 52 RDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLTFPRIQG 111 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 + G + ++GEGV + G++V+ F + N D + D G G DG Sbjct: 112 TDTVGHIVAVGEGVDRARIGERVMVDF--------SIYNRDDDSLADIDYMGHG--RDG- 160 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY + + + ++ C + TG ++ Sbjct: 161 -----------------GYAEYMALPAENAHVVATDLTDIELATFCCAYLTGE-RMLERA 202 Query: 200 KVKPGSTCVVFGL-GGVGLSVIMGCKSAGA 228 ++ G T +V G GGVG ++I ++ GA Sbjct: 203 RLAAGETVLVTGASGGVGSAIIQLARARGA 232 >2WEK-A nrPDB Length = 341 Score = 34.3 bits (77), Expect = 0.088, Method: Compositional matrix adjust. Identities = 41/157 (26%), Positives = 70/157 (44%), Gaps = 8/157 (5%) Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 + R+T G+ V +M +F EYTVV +S+A + PE + L+ G +T Y + + Sbjct: 82 SARYTV-GQAVA-YMAPGSFAEYTVV-PASIATPVPSVKPEYLTLLVSG-TTAYISLKEL 137 Query: 199 GKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 G + G +V G M +IG + +K ++G I+ K Sbjct: 138 GGLSEGKKVLVTAAAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLGCDRPINYK-- 195 Query: 259 TKPISEVLSEMTGNNVGYTFEVIG--HLETMIDALAS 293 T+P+ VL + V +E +G + +DALA+ Sbjct: 196 TEPVGTVLKQEYPEGVDVVYESVGGAMFDLAVDALAT 232 >4DVJ-A nrPDB Length = 363 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 47/97 (48%), Gaps = 7/97 (7%) Query: 13 MGTAGKVIKCKAAVLWEQKQPF----SIEEIEVAPPKT--KEVRIKILATGICRTDDHVI 66 +GT + AV + + P S+ +IE+ P ++ +++ A + D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 67 KGTMVSKFPV-IVGHEATGIVESIGEGVTTVKPGDKV 102 + T ++G++A GIV ++G VT +PGD+V Sbjct: 73 RSTPPDGTDWKVIGYDAAGIVSAVGPDVTLFRPGDEV 109 >2VWH-A nrPDB Length = 357 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 8/66 (12%) Query: 44 PKTKEVRIKILATGICRTDDHVIKGTMVSKFP-----VIVGHEATGIVESIGEGVTTVKP 98 P++ E ++ L G+ TD VI G FP +++GHEA G+V + T ++ Sbjct: 23 PESGEALVRTLRVGVDGTDHEVIAGGH-GGFPEGEDHLVLGHEAVGVV--VDPNDTELEE 79 Query: 99 GDKVIP 104 GD V+P Sbjct: 80 GDIVVP 85 >4IDE-A nrPDB Length = 332 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 33/67 (49%), Gaps = 5/67 (7%) Query: 41 VAPPKTKE--VRIKILATGICRTDDHVIKGTMV---SKFPVIVGHEATGIVESIGEGVTT 95 VA P+ KE V IK++A + D G S P I G++ G+V +G VT Sbjct: 45 VAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTK 104 Query: 96 VKPGDKV 102 K GD+V Sbjct: 105 FKVGDEV 111 >5LB9-A nrPDB Length = 385 Score = 30.8 bits (68), Expect = 1.1, Method: Compositional matrix adjust. Identities = 30/108 (27%), Positives = 48/108 (44%), Gaps = 23/108 (21%) Query: 17 GKVIKCKAAVLWEQK---------QPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK 67 G+ + AVL+ Q Q F I++ +AP EV +K L + + +D + I+ Sbjct: 19 GRHMITAQAVLYTQHGEPKDVLFTQSFEIDDDNLAP---NEVIVKTLGSPVNPSDINQIQ 75 Query: 68 GTMVSKFPVIVGHEAT---------GIVE--SIGEGVTTVKPGDKVIP 104 G SK G T G+ E +G V++++ GD VIP Sbjct: 76 GVYPSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIP 123 >1V9L-A nrPDB Length = 421 Score = 30.4 bits (67), Expect = 1.5, Method: Compositional matrix adjust. Identities = 24/91 (26%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 160 EYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVK-------PGSTCVVFGL 212 EY+ + +V + + PPE ++TG+G AV T ++ G T + G+ Sbjct: 159 EYSKIKGYNVPGVFTSKPPELWGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQGM 218 Query: 213 GGVGLSVIMGCKSAGASRIIGIDLNKDKFEK 243 G VG + GA I D+N + K Sbjct: 219 GNVGRWTAYWLEKMGAKVIAVSDINGVAYRK 249 >2EGU-A nrPDB Length = 308 Score = 30.0 bits (66), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 194 AAVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 AA K GK+KPG T V G G+GL+++ K A ++ ++ ++ A GA Sbjct: 55 AAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAEL 114 Query: 252 CISP 255 ++P Sbjct: 115 VLTP 118 >4HDR-A nrPDB Length = 348 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 2/57 (3%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT 69 MG AG + LW +K + ++ P T+E I+ + TGI +D V G Sbjct: 117 MGVAGDLSYVPG--LWHRKIAYGTQDFTEGPAMTREQAIQAVETGIDIVNDRVKHGN 171 >1MV8-A nrPDB Length = 436 Score = 29.6 bits (65), Expect = 2.4, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 22/34 (64%), Gaps = 1/34 (2%) Query: 209 VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFE 242 +FGLG VG +V GC SA +IG+D++ K + Sbjct: 5 IFGLGYVG-AVCAGCLSARGHEVIGVDVSSTKID 37 >2VN8-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/49 (38%), Positives = 27/49 (55%), Gaps = 4/49 (8%) Query: 55 ATGICRTDDHV-IKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKV 102 A + R HV IKG +FP+ +G + +G+V G V KPGD+V Sbjct: 77 ALNMKRDPLHVKIKG---EEFPLTLGRDVSGVVMECGLDVKYFKPGDEV 122 >6G1Y-A nrPDB Length = 507 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 31/126 (24%), Positives = 48/126 (38%), Gaps = 16/126 (12%) Query: 249 ATECISPKDSTKPISEVLSEMTGNNVGYTFEV---------IGHLETMIDA---LASCHM 296 A SP+ + P+ + +EM G +V I H +D LA+ H Sbjct: 276 ACHHYSPRVLSMPV-RIAAEMFGEFFSMHLQVLKQKRRLDTINHAHAALDRFLRLAAHHA 334 Query: 297 NYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQ 356 N +V A ++ D + L+ G W G G D +P+L F+A + Sbjct: 335 NIEELLVDSFQDFADLMPCDGVGLWVGNNWHG--HGATPPHDAIPRL-ARFVASASEGRV 391 Query: 357 LITHVL 362 TH L Sbjct: 392 WATHAL 397 >1JGT-A nrPDB Length = 513 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 19/73 (26%), Positives = 35/73 (47%), Gaps = 3/73 (4%) Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKD---KFEKAMAVGATECISPK 256 +V PG T +V GG+ S + C A + + + D +F +A AV + Sbjct: 237 RVTPGDTPLVVLSGGIDSSGVAACAHRAAGELDTVSMGTDTSNEFREARAVVDHLRTRHR 296 Query: 257 DSTKPISEVLSEM 269 + T P +E+L+++ Sbjct: 297 EITIPTTELLAQL 309 >4A10-A nrPDB Length = 447 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 56/267 (20%), Positives = 100/267 (37%), Gaps = 49/267 (18%) Query: 77 IVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLA 136 ++G + +G+V G GV KPGD VI + E + DG L G Sbjct: 112 VLGSDCSGVVVRTGIGVRRWKPGDHVI-VHPAHVDEQEPATHGDGMLGTEQRAWG----- 165 Query: 137 DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAV 196 F N EY VV S + E+ + T Y V Sbjct: 166 -----FET---------NFGGLAEYGVVRASQLLPKPAHLTWEEAAVSPLCAGTAYRMLV 211 Query: 197 --KTGKVKPGSTCVVFGL---------------GGVGLSVIMGCKSAGASRIIGIDLNKD 239 + ++K G +++G GG+ ++V+ + A R +G DL + Sbjct: 212 SDRGAQMKQGDIVLIWGASGGLGSYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVIN 271 Query: 240 KFEKAMAVGATECIS--PK---DSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASC 294 + E +G T+ I+ P+ ++ + +++++ E G FE G + + + + Sbjct: 272 RAE----LGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGRVTFGLSVIVA- 326 Query: 295 HMNYGTSVVVGVPPSAKMLTYDPMLLF 321 G +VV S + T+D L+ Sbjct: 327 --RRGGTVVTCGSSSGYLHTFDNRYLW 351 >2CF5-A nrPDB Length = 357 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 4/46 (8%) Query: 33 PFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM-VSKFPVI 77 P++ E P ++V I+I+ GIC TD H K + +S +P++ Sbjct: 24 PYTYTLRETGP---EDVNIRIICCGICHTDLHQTKNDLGMSNYPMV 66 >3ZWA-A nrPDB Length = 742 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 247 +ST GA+ KT +P S+ V GLG +G + + G S ++ ++ + + + A + Sbjct: 300 WSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGIS-VVAVESDPKQLDAAKKI 358 >1ZCJ-A nrPDB Length = 463 Score = 28.5 bits (62), Expect = 5.6, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 247 +ST GA+ KT +P S+ V GLG +G + + G S ++ ++ + + + A + Sbjct: 21 WSTPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARVGIS-VVAVESDPKQLDAAKKI 79 >2XRX-A nrPDB Length = 459 Score = 28.1 bits (61), Expect = 6.0, Method: Compositional matrix adjust. Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 9/56 (16%) Query: 76 VIVGHEA----TG--IVESIGEG-VTTVKPGDKVIPLFLPQCRE--CNACRNPDGN 122 +++GHE+ TG + +GE V V+ DK I +FL QCR CR+ GN Sbjct: 59 LLLGHESHVPETGDFLATYMGEDPVVMVRQKDKSIKVFLNQCRHRGMRICRSDAGN 114 >5ILO-A nrPDB Length = 271 Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 28/51 (54%), Gaps = 2/51 (3%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDL--NKDKFEKAMAVGATECI 253 + V G GG+GL V +AGA+++ IDL N ++F K A T+ + Sbjct: 17 NAVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSV 67 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1D1T-A nrPDB 485 e-137 1HSZ-A nrPDB 472 e-133 1HSO-A nrPDB 471 e-133 1U3W-A nrPDB 469 e-133 1EE2-A nrPDB 462 e-130 3COS-A nrPDB 441 e-124 4DLA-A nrPDB 426 e-119 1MC5-A nrPDB 424 e-119 4JJI-A nrPDB 419 e-118 1CDO-A nrPDB 415 e-116 1E3E-A nrPDB 415 e-116 4RQU-A nrPDB 408 e-114 1P0F-A nrPDB 397 e-111 3PII-A nrPDB 303 8e-83 5TNX-A nrPDB 303 8e-83 2DFV-A nrPDB 302 2e-82 3MEQ-A nrPDB 298 3e-81 1F8F-A nrPDB 293 7e-80 3GFB-A nrPDB 292 2e-79 1PL8-A nrPDB 290 1e-78 4Z6K-A nrPDB 288 2e-78 3QE3-A nrPDB 285 2e-77 1LLU-A nrPDB 284 6e-77 3S2F-A nrPDB 279 1e-75 2EER-A nrPDB 279 1e-75 2DQ4-A nrPDB 279 2e-75 4CPD-A nrPDB 275 2e-74 6N7L-A nrPDB 270 7e-73 1E3J-A nrPDB 269 2e-72 5KIA-A nrPDB 265 3e-71 5YLN-A nrPDB 263 1e-70 1H2B-A nrPDB 257 7e-69 4EEZ-A nrPDB 256 1e-68 1R37-A nrPDB 252 2e-67 5ENV-A nrPDB 248 2e-66 5VM2-A nrPDB 248 3e-66 4OH1-A nrPDB 244 3e-65 1YKF-A nrPDB 243 1e-64 3FSR-A nrPDB 243 1e-64 3FPC-A nrPDB 242 2e-64 1UUF-A nrPDB 239 1e-63 4ILK-A nrPDB 239 2e-63 5H82-A nrPDB 238 3e-63 5YAT-A nrPDB 237 8e-63 3FPL-A nrPDB 233 7e-62 3TWO-A nrPDB 233 8e-62 1KEV-A nrPDB 233 8e-62 4EJ6-A nrPDB 233 1e-61 5K1S-A nrPDB 229 2e-60 2H6E-A nrPDB 228 5e-60 5Z0C-A nrPDB 226 9e-60 1YQX-A nrPDB 226 2e-59 3M6I-A nrPDB 225 3e-59 4GKV-A nrPDB 223 7e-59 2OUI-A nrPDB 223 1e-58 6DKH-A nrPDB 222 2e-58 3IP1-A nrPDB 221 6e-58 4OAQ-A nrPDB 220 9e-58 6FG0-A nrPDB 217 6e-57 1Q1N-A nrPDB 211 4e-55 4UEJ-A nrPDB 209 1e-54 5VKT-A nrPDB 209 2e-54 3UOG-A nrPDB 203 9e-53 6C49-A nrPDB 194 6e-50 5FI5-A nrPDB 191 6e-49 5H83-A nrPDB 189 2e-48 4JLW-A nrPDB 184 7e-47 1YB5-A nrPDB 180 8e-46 3WLE-A nrPDB 174 4e-44 1KOL-A nrPDB 174 5e-44 2DPH-A nrPDB 172 3e-43 3QWB-A nrPDB 172 3e-43 1WLY-A nrPDB 150 7e-37 1QOR-A nrPDB 143 1e-34 3JYN-A nrPDB 142 2e-34 2VCY-A nrPDB 129 2e-30 3FBG-A nrPDB 129 2e-30 2CDC-A nrPDB 103 1e-22 Sequences not found previously or not previously below threshold: 2CF5-A nrPDB 159 2e-39 4RVS-A nrPDB 138 4e-33 4J6F-A nrPDB 134 8e-32 2OBY-A nrPDB 134 8e-32 3HZZ-A nrPDB 128 4e-30 4A10-A nrPDB 119 1e-27 4DVJ-A nrPDB 117 6e-27 3SLK-A nrPDB 115 3e-26 2VN8-A nrPDB 115 3e-26 4Y1B-A nrPDB 113 1e-25 2WEK-A nrPDB 113 1e-25 5A3V-A nrPDB 112 2e-25 3TQH-A nrPDB 112 2e-25 4EYE-A nrPDB 112 3e-25 4A27-A nrPDB 111 5e-25 4IDE-A nrPDB 109 3e-24 3B70-A nrPDB 105 2e-23 2VWH-A nrPDB 101 7e-22 5LB9-A nrPDB 83 2e-16 1V3V-A nrPDB 79 4e-15 5GXF-A nrPDB 77 1e-14 2Y05-A nrPDB 75 6e-14 3WID-A nrPDB 73 2e-13 1O89-A nrPDB 72 5e-13 2J3K-A nrPDB 64 2e-10 2VNA-A nrPDB 58 7e-09 2ZB3-A nrPDB 54 9e-08 1ZCJ-A nrPDB 44 2e-04 3ZWA-A nrPDB 42 3e-04 2EGU-A nrPDB 41 8e-04 1X14-A nrPDB 41 0.001 4DIO-A nrPDB 40 0.002 6BII-A nrPDB 38 0.009 3MGG-A nrPDB 38 0.009 1BW9-B nrPDB 38 0.009 2VHY-A nrPDB 37 0.010 1XLT-A nrPDB 37 0.012 3VPX-A nrPDB 37 0.019 4XIJ-A nrPDB 37 0.020 6C55-A nrPDB 37 0.020 3X2F-A nrPDB 36 0.026 5Z1Z-A nrPDB 36 0.027 1CYD-A nrPDB 36 0.033 2B25-A nrPDB 36 0.034 5EKU-A nrPDB 35 0.050 4M36-A nrPDB 35 0.050 4GCM-A nrPDB 35 0.052 1VH3-A nrPDB 35 0.056 1V9L-A nrPDB 35 0.060 3KYD-B nrPDB 35 0.061 3KYC-B nrPDB 35 0.061 1I9G-A nrPDB 35 0.069 5F8E-A nrPDB 34 0.084 5ILO-A nrPDB 34 0.085 2O23-A nrPDB 34 0.097 4N7R-A nrPDB 34 0.11 5JXW-A nrPDB 34 0.11 4K2X-A nrPDB 34 0.12 5AOV-A nrPDB 34 0.12 4CUK-A nrPDB 34 0.12 1DXY-A nrPDB 34 0.14 6ACF-A nrPDB 34 0.15 5UYY-A nrPDB 34 0.16 3D3W-A nrPDB 33 0.18 3G1U-A nrPDB 33 0.20 4K28-A nrPDB 33 0.22 1JWB-B nrPDB 33 0.22 1XDW-A nrPDB 33 0.22 5JJC-A nrPDB 33 0.22 1ZFN-A nrPDB 33 0.22 1NVM-B nrPDB 33 0.29 2EKL-A nrPDB 32 0.32 4WO8-A nrPDB 32 0.32 4YRY-B nrPDB 32 0.33 5JE5-A nrPDB 32 0.34 2HAE-A nrPDB 32 0.35 5U9P-A nrPDB 32 0.36 6APH-A nrPDB 32 0.37 4XGI-A nrPDB 32 0.38 3GDH-A nrPDB 32 0.38 3EGI-A nrPDB 32 0.38 4INE-A nrPDB 32 0.39 2HMT-A nrPDB 32 0.40 1E3W-A nrPDB 32 0.40 1V8B-A nrPDB 32 0.42 5BUT-A nrPDB 32 0.43 4FS8-A nrPDB 32 0.43 2YVG-A nrPDB 32 0.44 2WWR-A nrPDB 32 0.53 2ISQ-A nrPDB 32 0.53 4COO-A nrPDB 32 0.54 3X43-A nrPDB 32 0.55 1W1U-A nrPDB 32 0.56 1M54-A nrPDB 32 0.56 3JTJ-A nrPDB 32 0.57 3CJR-A nrPDB 32 0.57 3AOE-A nrPDB 32 0.58 5MMS-A nrPDB 32 0.61 4J90-A nrPDB 32 0.62 2BHS-A nrPDB 32 0.62 3HM2-A nrPDB 32 0.64 2AS0-A nrPDB 32 0.66 3FBT-A nrPDB 31 0.74 6J0Z-C nrPDB 31 0.75 3WGE-A nrPDB 31 0.76 6IQV-A nrPDB 31 0.82 4PZE-A nrPDB 31 0.83 3BKX-A nrPDB 31 0.83 2ZJ1-A nrPDB 31 0.88 4E4T-A nrPDB 31 0.93 3N58-A nrPDB 31 0.95 1GPJ-A nrPDB 31 1.0 5ZBK-A nrPDB 31 1.0 4IZO-A nrPDB 31 1.1 5D84-A nrPDB 31 1.1 5TQV-A nrPDB 30 1.2 3TNL-A nrPDB 30 1.2 3NJ4-A nrPDB 30 1.2 6DLL-A nrPDB 30 1.3 3GG9-A nrPDB 30 1.3 6GBN-A nrPDB 30 1.3 2NVU-B nrPDB 30 1.3 1YOV-B nrPDB 30 1.3 4DIM-A nrPDB 30 1.3 2EEZ-A nrPDB 30 1.3 6GME-A nrPDB 30 1.3 3OC4-A nrPDB 30 1.4 2JC3-A nrPDB 30 1.4 3H9U-A nrPDB 30 1.4 3DC2-A nrPDB 30 1.4 2RIR-A nrPDB 30 1.5 2EXX-A nrPDB 30 1.5 3OND-A nrPDB 30 1.5 1QO8-A nrPDB 30 1.6 4F86-A nrPDB 30 1.7 3HDH-A nrPDB 30 1.7 2BRY-A nrPDB 30 1.7 4X4J-A nrPDB 30 1.7 4TXK-A nrPDB 30 1.7 3EMK-A nrPDB 30 1.7 1PBY-A nrPDB 30 1.8 5WAB-A nrPDB 30 1.8 3GRP-A nrPDB 30 1.9 1HL3-A nrPDB 30 1.9 1G6Q-1 nrPDB 30 1.9 1DOD-A nrPDB 30 2.1 1LTH-T nrPDB 30 2.2 5NMX-A nrPDB 30 2.2 2YQ5-A nrPDB 30 2.2 6HNS-A nrPDB 30 2.3 3HWR-A nrPDB 30 2.4 3H8E-A nrPDB 30 2.5 4FHN-X nrPDB 30 2.5 3IC9-A nrPDB 30 2.5 3H5A-A nrPDB 30 2.5 2D1F-A nrPDB 30 2.5 1F14-A nrPDB 30 2.6 5B2L-A nrPDB 30 2.6 4XRR-A nrPDB 29 2.7 6BQC-A nrPDB 29 3.1 5VMT-A nrPDB 29 3.1 5XGV-A nrPDB 29 3.3 2LDB-A nrPDB 29 3.3 5OHX-A nrPDB 29 3.5 3FEO-A nrPDB 29 3.5 3ZZN-A nrPDB 29 3.6 3LLV-A nrPDB 29 3.6 5JFC-L nrPDB 29 3.7 3AOE-E nrPDB 29 3.7 4PRK-A nrPDB 29 3.9 3K8Z-A nrPDB 29 3.9 2YFH-A nrPDB 29 4.0 5VJ7-A nrPDB 29 4.0 4RDI-A nrPDB 29 4.1 4OFX-A nrPDB 29 4.1 3VH2-A nrPDB 29 4.3 3T7E-A nrPDB 29 4.3 3PPI-A nrPDB 29 4.3 1BG6-A nrPDB 28 4.6 3RWB-A nrPDB 28 4.9 5UOG-A nrPDB 28 5.1 2UVD-A nrPDB 28 5.1 6FZI-A nrPDB 28 5.2 3MOG-A nrPDB 28 5.3 3JTM-A nrPDB 28 5.4 4FXS-A nrPDB 28 5.9 4X28-D nrPDB 28 6.2 4FEZ-A nrPDB 28 6.2 1LSS-A nrPDB 28 6.5 4EJ0-A nrPDB 28 7.0 1WG8-A nrPDB 28 7.0 5MKK-A nrPDB 28 7.4 4LRT-B nrPDB 28 7.4 3NIX-A nrPDB 28 7.5 5UJU-A nrPDB 28 8.2 3NNK-A nrPDB 28 8.4 3FG2-P nrPDB 28 8.5 4P4L-A nrPDB 28 9.2 1V9C-A nrPDB 28 9.2 4KUG-A nrPDB 28 9.3 2A33-A nrPDB 28 9.6 1QP8-A nrPDB 28 9.7 3II4-A nrPDB 27 10.0 >1D1T-A nrPDB Length = 373 Score = 485 bits (1248), Expect = e-137, Method: Composition-based stats. Identities = 372/373 (99%), Positives = 373/373 (100%) Query: 14 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 73 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK Sbjct: 1 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 60 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG Sbjct: 61 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 120 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 VLADGTTRFTCKGKPVHHF+NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG Sbjct: 121 VLADGTTRFTCKGKPVHHFLNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 180 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI Sbjct: 181 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 240 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML Sbjct: 241 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 300 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL Sbjct: 301 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 360 Query: 374 LNSGQSIRTVLTF 386 LNSGQSIRTVLTF Sbjct: 361 LNSGQSIRTVLTF 373 >1HSZ-A nrPDB Length = 374 Score = 472 bits (1215), Expect = e-133, Method: Composition-based stats. Identities = 259/373 (69%), Positives = 315/373 (84%), Gaps = 1/373 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWE K+PFSIE++EVAPPK EVRIK++A GICRTDDHV+ G +V+ Sbjct: 2 TAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICRTDDHVVSGNLVTPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 133 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ RG Sbjct: 62 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNPRG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 L DGT RFTC+GKP+HHF+ TSTF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 122 TLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 +AV KV PGSTC VFGLGGVGLS +MGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 182 SAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP+++ L Sbjct: 242 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQNL 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 + +PMLL TGRTWKG V+GG KS++ +PKLV +F+AKKF LD LITHVLPF+KI+EGF+L Sbjct: 302 SINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 361 Query: 374 LNSGQSIRTVLTF 386 L+SG+SIRTVLTF Sbjct: 362 LHSGKSIRTVLTF 374 >1HSO-A nrPDB Length = 374 Score = 471 bits (1211), Expect = e-133, Method: Composition-based stats. Identities = 256/373 (68%), Positives = 312/373 (83%), Gaps = 1/373 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GIC TDDHV+ GTMV+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVTPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 133 PVI+GHEA GIVES+GEGVTTVKPGDKVIPL +PQC +C C+NP+ N C+++D++ +G Sbjct: 62 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNPQG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 L DGT+RFTC+ KP+HHF+ STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 122 TLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 +AV KV PGSTC VFGLGGVGLS IMGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 182 SAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ L Sbjct: 242 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNL 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 + +PMLL TGRTWKG + GG KS++ VPKLV +F+AKKF LD LITHVLPF+KI+EGF+L Sbjct: 302 SMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGFDL 361 Query: 374 LNSGQSIRTVLTF 386 L+SG+SIRT+L F Sbjct: 362 LHSGKSIRTILMF 374 >1U3W-A nrPDB Length = 374 Score = 469 bits (1207), Expect = e-133, Method: Composition-based stats. Identities = 259/373 (69%), Positives = 313/373 (83%), Gaps = 1/373 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK EVRIK++A GICR+D+HV+ G +V+ Sbjct: 2 TAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG-RG 133 PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C C+NP+ N C+++D+ RG Sbjct: 62 PVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 L DGT RFTC GKP+HHF+ STF++YTVVDE++VAKID A+P EKVCLIGCGFSTGYG Sbjct: 122 TLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 +AVK KV PGSTC VFGLGGVGLSV+MGCK+AGA+RII +D+NKDKF KA +GATECI Sbjct: 182 SAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D KPI EVL EMT V ++FEVIG L+TM+ +L CH GTSV+VGVPP ++ L Sbjct: 242 NPQDYKKPIQEVLKEMTDGGVDFSFEVIGQLDTMMASLLCCHEACGTSVIVGVPPDSQNL 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 + +PMLL TGRTWKG +FGG KS++ VPKLV +F+AKKF LD LIT+VLPF+KI+EGF+L Sbjct: 302 SINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNVLPFEKINEGFDL 361 Query: 374 LNSGQSIRTVLTF 386 L SG+SIRTVLTF Sbjct: 362 LRSGKSIRTVLTF 374 >1EE2-A nrPDB Length = 373 Score = 462 bits (1188), Expect = e-130, Method: Composition-based stats. Identities = 262/372 (70%), Positives = 319/372 (85%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF 74 TAGKVIKCKAAVLWEQK+PFSIEE+EVAPPK EVRIK++A GICR+DDHV+ GT+V+ Sbjct: 2 TAGKVIKCKAAVLWEQKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDDHVVSGTLVAPL 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGV 134 PVI GHEA GIVESIGEGVTTV+PGDKVIPLF+PQC +C+ C++P+GNLC+++ RG Sbjct: 62 PVIAGHEAAGIVESIGEGVTTVRPGDKVIPLFIPQCGKCSVCKHPEGNLCLKNLSMPRGT 121 Query: 135 LADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGA 194 + DGT+RFTC+GKP+HHF+ TSTF++YTVVDE SVAKID A+P EKVCL+GCGFSTGYG+ Sbjct: 122 MQDGTSRFTCRGKPIHHFLGTSTFSQYTVVDEISVAKIDAASPLEKVCLVGCGFSTGYGS 181 Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 AVK KV GSTC VFGLGGVGLSVIMGCK+AGA+RIIG+D+NKDKF KA VGATEC++ Sbjct: 182 AVKVAKVTQGSTCAVFGLGGVGLSVIMGCKAAGAARIIGVDINKDKFAKAKEVGATECVN 241 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 P+D KPI EVL+EM+ V ++FEVIG L+TM+ AL+ C YG SV+VGVPP ++ L+ Sbjct: 242 PQDYKKPIQEVLTEMSNGGVDFSFEVIGRLDTMVAALSCCQEAYGVSVIVGVPPDSQNLS 301 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELL 374 +PMLL +GRTWKG +FGG KS+D VPKLV +F+AKKF LD LITHVLPF+KI+EGF+LL Sbjct: 302 MNPMLLLSGRTWKGAIFGGFKSKDSVPKLVADFMAKKFALDPLITHVLPFEKINEGFDLL 361 Query: 375 NSGQSIRTVLTF 386 SG+SIRT+LTF Sbjct: 362 RSGKSIRTILTF 373 >3COS-A nrPDB Length = 381 Score = 441 bits (1133), Expect = e-124, Method: Composition-based stats. Identities = 222/380 (58%), Positives = 273/380 (71%), Gaps = 6/380 (1%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM-V 71 MGT GKVIKCKAA+ WE +P IEE+EVAPPK EVRI+I+AT +C TD VI Sbjct: 2 MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 61 Query: 72 SKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC-----IR 126 FPVIVGHEA GIVESIG GVT VKPGDKVIPL+ P CR+C C +P NLC ++ Sbjct: 62 LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 121 Query: 127 SDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGC 186 S + + ++ D T+RFTCKGKPV+HF TSTF++YTVV + ++AKIDD A E+VCL+GC Sbjct: 122 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 181 Query: 187 GFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 GFSTGYGAA+ KV PGSTC VFGLGGVGLS +MGCK+AGASRIIGID+N +KF KA A Sbjct: 182 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 241 Query: 247 VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGV 306 +GAT+C++P+D KPI EV+ E+T V + + G ETM AL +G+ +GV Sbjct: 242 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 301 Query: 307 PPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKK 366 +K LT P L GRT G FGG KS D +PKLVT++ KKF+LD L+TH LPF K Sbjct: 302 AAGSKGLTVFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 361 Query: 367 ISEGFELLNSGQSIRTVLTF 386 ISE F+L+N G+SIRT+L F Sbjct: 362 ISEAFDLMNQGKSIRTILIF 381 >4DLA-A nrPDB Length = 396 Score = 426 bits (1094), Expect = e-119, Method: Composition-based stats. Identities = 190/375 (50%), Positives = 252/375 (67%), Gaps = 3/375 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK- 73 T G+VI CKAAV WE +P IE+++VAPP+ EVR+K+L T +C TD + G Sbjct: 20 TQGQVITCKAAVAWEPNKPLVIEDVQVAPPQAGEVRVKVLYTALCHTDAYTWSGKDPEGL 79 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIR-SDITGR 132 FP ++GHEA GIVES+GEGVT V+PGD VIP + +CREC C++ NLC + TG Sbjct: 80 FPCVLGHEAAGIVESVGEGVTEVQPGDHVIPCYQAECRECKFCKSGKTNLCGKVRAATGV 139 Query: 133 GVLA-DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191 GV+ D +RF+ GKP++HFM TSTF++YTVV + SVAKID AP EKVCL+GCG TG Sbjct: 140 GVMMNDRKSRFSINGKPIYHFMGTSTFSQYTVVHDVSVAKIDPVAPLEKVCLLGCGVPTG 199 Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 GA T KV+PGS VFGLG VGL+V G K+AGASRIIGID++ KF++A G TE Sbjct: 200 LGAVWNTAKVEPGSIVAVFGLGTVGLAVAEGAKAAGASRIIGIDIDSKKFDRAKNFGVTE 259 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 I+PK+ +PI +V+ ++T V Y+FE IG++ M AL CH +GTSV+VGV S + Sbjct: 260 FINPKEHEQPIQQVIVDLTDGGVDYSFECIGNVSVMRSALECCHKGWGTSVIVGVAASGQ 319 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 ++ P L TGR WKG FGG KSR VP LV ++L K+ +D+ ITH + I++ F Sbjct: 320 EISTRPFQLVTGRVWKGTAFGGFKSRSQVPSLVDKYLKKEIKVDEYITHNMTLADINKAF 379 Query: 372 ELLNSGQSIRTVLTF 386 +L++ G +R VL Sbjct: 380 DLMHDGDCLRVVLDM 394 >1MC5-A nrPDB Length = 374 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 227/371 (61%), Positives = 282/371 (76%), Gaps = 2/371 (0%) Query: 16 AGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-F 74 A +VIKCKAAV WE +P SIEEIEVAPPK EVRIKI+AT +C TD + + G F Sbjct: 2 ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSGADPEGCF 61 Query: 75 PVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDIT-GRG 133 PVI+GHE GIVES+GEGVT +K GD VIPL++PQC EC C NP NLC + +T G+G Sbjct: 62 PVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQGKG 121 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYG 193 ++ DGT+RFTCKGK + H+M TSTF+EYTVV + SVAKID AP +KVCL+GCG STGYG Sbjct: 122 LMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTGYG 181 Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 AAV T K++PGS C VFGLGGVGL+VIMGCK AGASRIIG+D+NKDKF +A GATECI Sbjct: 182 AAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATECI 241 Query: 254 SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML 313 +P+D +KPI EVL EMT V Y+FE IG+++ M AL +CH +G SVVVGV S + + Sbjct: 242 NPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGEEI 301 Query: 314 TYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL 373 P L TGRTWKG FGG KS + VPKLV+E+++KK +D+ +TH L F +I++ FEL Sbjct: 302 ATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAFEL 361 Query: 374 LNSGQSIRTVL 384 ++SG+SIRTV+ Sbjct: 362 MHSGKSIRTVV 372 >4JJI-A nrPDB Length = 378 Score = 419 bits (1078), Expect = e-118, Method: Composition-based stats. Identities = 190/374 (50%), Positives = 250/374 (66%), Gaps = 3/374 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK- 73 T G+VI CKAAV +E +P IE+++VAPP+ EVRIKIL T +C TD + G Sbjct: 2 TQGQVITCKAAVAYEPNKPLVIEDVQVAPPQAGEVRIKILYTALCHTDAYTWSGKDPEGL 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIR-SDITGR 132 FP I+GHEA GIVES+GEGVT V+ GD VIP + +CREC C++ NLC + TG Sbjct: 62 FPCILGHEAAGIVESVGEGVTEVQAGDHVIPCYQAECRECKFCKSGKTNLCGKVRSATGV 121 Query: 133 GVLA-DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191 G++ D +RF+ GKP++HFM TSTF++YTVV + SVAKID AP +KVCL+GCG TG Sbjct: 122 GIMMNDRKSRFSVNGKPIYHFMGTSTFSQYTVVHDVSVAKIDPTAPLDKVCLLGCGVPTG 181 Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 GA T KV+PGS +FGLG VGL+V G K+AGASRIIGID++ K+E A G E Sbjct: 182 LGAVWNTAKVEPGSNVAIFGLGTVGLAVAEGAKTAGASRIIGIDIDSKKYETAKKFGVNE 241 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 ++PKD KPI EV+ ++T V Y+FE IG++ M AL CH +GTSV+VGV S + Sbjct: 242 FVNPKDHDKPIQEVIVDLTDGGVDYSFECIGNVSVMRAALECCHKGWGTSVIVGVAASGQ 301 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 ++ P L TGR WKG FGG KSR VP LV +++ K+ +D+ ITH L +I++ F Sbjct: 302 EISTRPFQLVTGRVWKGTAFGGFKSRTQVPWLVEKYMNKEIKVDEYITHNLTLGEINKAF 361 Query: 372 ELLNSGQSIRTVLT 385 +LL+ G +R VL Sbjct: 362 DLLHEGTCLRCVLD 375 >1CDO-A nrPDB Length = 374 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 197/374 (52%), Positives = 261/374 (69%), Gaps = 3/374 (0%) Query: 15 TAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDD-HVIKGTMVSK 73 T GKVIKCKAAV WE +P IEEIEV P E+RIKI+ATG+C TD H+ +G Sbjct: 2 TVGKVIKCKAAVAWEANKPLVIEEIEVDVPHANEIRIKIIATGVCHTDLYHLFEGKHKDG 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDIT-GR 132 FPV++GHE GIVES+G GVT +PG+KVIPLF+ QC EC C++P N C++ Sbjct: 62 FPVVLGHEGAGIVESVGPGVTEFQPGEKVIPLFISQCGECRFCQSPKTNQCVKGWANESP 121 Query: 133 GVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGY 192 V++ TRFTCKG+ V F+ TSTF++YTVV++ +VAKID +AP + VCL+GCG STG+ Sbjct: 122 DVMSPKETRFTCKGRKVLQFLGTSTFSQYTVVNQIAVAKIDPSAPLDTVCLLGCGVSTGF 181 Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 GAAV T KV+PGSTC VFGLG VGL+ +MGC SAGA RII +DLN DKFEKA GAT+ Sbjct: 182 GAAVNTAKVEPGSTCAVFGLGAVGLAAVMGCHSAGAKRIIAVDLNPDKFEKAKVFGATDF 241 Query: 253 ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKM 312 ++P D ++PIS+VLS+MT V ++ E +G++ M +AL SC +G SV+VG Sbjct: 242 VNPNDHSEPISQVLSKMTNGGVDFSLECVGNVGVMRNALESCLKGWGVSVLVGWTDLHD- 300 Query: 313 LTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 372 + P+ L GRTWKG +FGG K +D VPK+V +L KK LD+ ITH +P + +++ + Sbjct: 301 VATRPIQLIAGRTWKGSMFGGFKGKDGVPKMVKAYLDKKVKLDEFITHRMPLESVNDAID 360 Query: 373 LLNSGQSIRTVLTF 386 L+ G+ IRTVL+ Sbjct: 361 LMKHGKCIRTVLSL 374 >1E3E-A nrPDB Length = 376 Score = 415 bits (1067), Expect = e-116, Method: Composition-based stats. Identities = 192/378 (50%), Positives = 262/378 (69%), Gaps = 7/378 (1%) Query: 14 GTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK 73 GT GKVIKCKAA+ W+ P IEEIEV+PPK EVRI+++AT +C TD + + Sbjct: 1 GTQGKVIKCKAAIAWKTGSPLCIEEIEVSPPKACEVRIQVIATCVCPTDINATDPKKKAL 60 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC-----IRSD 128 FPV++GHE GIVES+G GVT KPGDKVIP F PQC+ C C +P NLC + Sbjct: 61 FPVVLGHECAGIVESVGPGVTNFKPGDKVIPFFAPQCKRCKLCLSPLTNLCGKLRNFKYP 120 Query: 129 ITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGF 188 + ++ D T+RFTCKG+ ++HFM S+F++YTVV E+++A++DD A E+VCLIGCGF Sbjct: 121 TIDQELMEDRTSRFTCKGRSIYHFMGVSSFSQYTVVSEANLARVDDEANLERVCLIGCGF 180 Query: 189 STGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 S+GYGAA+ T KV PGSTC VFGLG VGLS I+GCK AGASRII ID+N +KF KA A+G Sbjct: 181 SSGYGAAINTAKVTPGSTCAVFGLGCVGLSAIIGCKIAGASRIIAIDINGEKFPKAKALG 240 Query: 249 ATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP 308 AT+C++P++ KP+ +V++E+T V Y+ + G +T+ A+ + +G+ VVG Sbjct: 241 ATDCLNPRELDKPVQDVITELTAGGVDYSLDCAGTAQTLKAAVDCTVLGWGSCTVVGAKV 300 Query: 309 SAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKIS 368 + ++L GR+ G FGG KS D VP LV+++ KKFDLD L+TH LPF+ I+ Sbjct: 301 DEMTIPTVDVIL--GRSINGTFFGGWKSVDSVPNLVSDYKNKKFDLDLLVTHALPFESIN 358 Query: 369 EGFELLNSGQSIRTVLTF 386 + +L+ G+SIRT+LTF Sbjct: 359 DAIDLMKEGKSIRTILTF 376 >4RQU-A nrPDB Length = 375 Score = 408 bits (1049), Expect = e-114, Method: Composition-based stats. Identities = 169/372 (45%), Positives = 240/372 (64%), Gaps = 3/372 (0%) Query: 18 KVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-FPV 76 ++I+CKAAV WE +P IEE+EVAPP+ EVRIKIL T +C TD + + + FP Sbjct: 2 QIIRCKAAVAWEAGKPLVIEEVEVAPPQKHEVRIKILFTSLCHTDVYFWEAKGQTPLFPR 61 Query: 77 IVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLC--IRSDITGRGV 134 I GHEA GIVES+GEGVT ++PGD V+P+F +C EC C + + N+C +R + G+ Sbjct: 62 IFGHEAGGIVESVGEGVTDLQPGDHVLPIFTGECGECRHCHSEESNMCDLLRINTERGGM 121 Query: 135 LADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGA 194 + DG +RF+ GKP++HF+ TSTF+EYTVV VAKI+ AP +KVC++ CG STG GA Sbjct: 122 IHDGESRFSINGKPIYHFLGTSTFSEYTVVHSGQVAKINPDAPLDKVCIVSCGLSTGLGA 181 Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 + K K G + +FGLG VGL G + AGASRIIG+D N +F++A G TEC++ Sbjct: 182 TLNVAKPKKGQSVAIFGLGAVGLGAAEGARIAGASRIIGVDFNSKRFDQAKEFGVTECVN 241 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 PKD KPI +V++EMT V + E G ++ MI A H +G +V+VGVP Sbjct: 242 PKDHDKPIQQVIAEMTDGGVDRSVECTGSVQAMIQAFECVHDGWGVAVLVGVPSKDDAFK 301 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELL 374 PM RT KG FG K + D+P +V +++ K+ +L++ ITH +PF +I++ F+ + Sbjct: 302 THPMNFLNERTLKGTFFGNYKPKTDIPGVVEKYMNKELELEKFITHTVPFSEINKAFDYM 361 Query: 375 NSGQSIRTVLTF 386 G+SIR ++T Sbjct: 362 LKGESIRCIITM 373 >1P0F-A nrPDB Length = 373 Score = 397 bits (1021), Expect = e-111, Method: Composition-based stats. Identities = 214/375 (57%), Positives = 278/375 (74%), Gaps = 3/375 (0%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS 72 M TAGK I CKAAV WE +P S+E I VAPPK EVRIKILA+GIC +D V+K + S Sbjct: 1 MCTAGKDITCKAAVAWEPHKPLSLETITVAPPKAHEVRIKILASGICGSDSSVLKEIIPS 60 Query: 73 KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG- 131 KFPVI+GHEA G+VESIG GVT VKPGDKVIPLF+PQC C AC++ + N C ++D+ Sbjct: 61 KFPVILGHEAVGVVESIGAGVTCVKPGDKVIPLFVPQCGSCRACKSSNSNFCEKNDMGAK 120 Query: 132 RGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191 G++AD T+RFTC+GKP+++ M TSTFTEYTVV + +VAKID AP E CLIGCGF+TG Sbjct: 121 TGLMADMTSRFTCRGKPIYNLMGTSTFTEYTVVADIAVAKIDPKAPLES-CLIGCGFATG 179 Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 YGAAV T KV PGSTC VFGLGGVG S I+GCK+AGASRIIG+ +KDKF KA+ +GATE Sbjct: 180 YGAAVNTAKVTPGSTCAVFGLGGVGFSAIVGCKAAGASRIIGVGTHKDKFPKAIELGATE 239 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 C++PKD KPI EV+ E T V Y E G +ETM++AL S + G +VV+G+ + Sbjct: 240 CLNPKDYDKPIYEVICEKTNGGVDYAVECAGRIETMMNALQSTYCGSGVTVVLGLASPNE 299 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 L DP+LL TGR+ KG VFGG K ++V +LV +++ KK +++ L++ L +I++ F Sbjct: 300 RLPLDPLLLLTGRSLKGSVFGGFKG-EEVSRLVDDYMKKKINVNFLVSTKLTLDQINKAF 358 Query: 372 ELLNSGQSIRTVLTF 386 ELL+SGQ +R+++ + Sbjct: 359 ELLSSGQGVRSIMIY 373 >3PII-A nrPDB Length = 339 Score = 303 bits (776), Expect = 8e-83, Method: Composition-based stats. Identities = 102/368 (27%), Positives = 151/368 (41%), Gaps = 37/368 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV--SKFPVIVGH 80 KAAV+ + K+P I+E+E EV ++I A G+C TD H G K P+I GH Sbjct: 2 KAAVVEQFKEPLKIKEVEKPTISYGEVLVRIKACGVCHTDLHAAHGDWPVKPKLPLIPGH 61 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E GIVE +G GVT +K GD+V IP C C+ C + LC G V Sbjct: 62 EGVGIVEEVGPGVTHLKVGDRVGIPWLYSACGHCDYCLSGQETLCEHQKNAGYSV----- 116 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY V KI D E+ I C T Y A+K Sbjct: 117 ---------------DGGYAEYCRAAADYVVKIPDNLSFEEAAPIFCAGVTTY-KALKVT 160 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 KPG ++G+GG G + K+ G + ++ +D+ +K E A +GA ++P Sbjct: 161 GAKPGEWVAIYGIGGFGHVAVQYAKAMGLN-VVAVDIGDEKLELAKELGADLVVNPLKED 219 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 ++ + E G + + + G V+VG+PP + Sbjct: 220 --AAKFMKEKVGGVHAAVVTAVSKPA--FQSAYNSIRRGGACVLVGLPPEEMPIPIF-DT 274 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ- 378 + G G + G K + + E K I V P +KI+E F+ + GQ Sbjct: 275 VLNGIKIIGSIVGTRKDLQEALQFAAEGKVKT------IIEVQPLEKINEVFDRMLKGQI 328 Query: 379 SIRTVLTF 386 + R VLT Sbjct: 329 NGRVVLTL 336 >5TNX-A nrPDB Length = 383 Score = 303 bits (776), Expect = 8e-83, Method: Composition-based stats. Identities = 112/360 (31%), Positives = 175/360 (48%), Gaps = 9/360 (2%) Query: 31 KQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIG 90 PFSIE + P+ EV ++++ATG+C TD V P ++GHE G+VE++G Sbjct: 27 GAPFSIEPARIRAPRGDEVLVRVVATGLCHTDLIVRDQYYPVPLPAVLGHEGAGVVEAVG 86 Query: 91 EGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRS-DITGRGVLADGTT--RFTCKGK 147 V T+ GD V+ L C C +C G C + + G ADG T R Sbjct: 87 PNVKTLAAGDHVV-LTYGACGHCASCAGGHGAYCRQFFALNFGGADADGQTALRDAAGEP 145 Query: 148 PVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTC 207 HF S+F Y + E++ K+ AP E + +GCG TG GA + + V+ GS+ Sbjct: 146 LHDHFFAQSSFASYALARENNAIKVPKEAPLELLGPLGCGIQTGAGAVINSLAVRTGSSF 205 Query: 208 VVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLS 267 FG G VG+S +M + AGA+ II +D+ + A+ +GAT I+ K+ + + + Sbjct: 206 ASFGAGAVGMSAVMAARIAGATTIIAVDIVPSRLALALELGATHAINSKEVD--VVDAIR 263 Query: 268 EMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYD-PMLLFTGRTW 326 E+TG V Y E G + + + GT VVG P +D LL G T Sbjct: 264 EITGGGVDYALESTGLPAVLSQGID-ALGSRGTMGVVGAPKLGTKAEFDVNSLLLGGHTI 322 Query: 327 KGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF 386 +G V G + +P+LV L +F D+L+ P ++I++ +SG +++ +L Sbjct: 323 RGIVEGDSVPQTFIPQLVQLHLQGRFPFDRLV-KFYPLEQINQAAADSSSGITLKPILRL 381 >2DFV-A nrPDB Length = 347 Score = 302 bits (773), Expect = 2e-82, Method: Composition-based stats. Identities = 99/359 (27%), Positives = 152/359 (42%), Gaps = 36/359 (10%) Query: 35 SIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS----KFPVIVGHEATGIVESIG 90 + E++V P EV IK+LAT IC TD H+ + + K P I+GHE G V IG Sbjct: 17 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEIG 76 Query: 91 EGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVH 150 GV ++ GD V C +C ACR ++C + I G Sbjct: 77 PGVEGIEVGDYVSVETHIVCGKCYACRRGQYHVCQNTKIFGV------------------ 118 Query: 151 HFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP--GSTCV 208 F EY VV ++ K + PPE L G AV T P G + + Sbjct: 119 --DTDGVFAEYAVVPAQNIWKNPKSIPPEYATL-----QEPLGNAVDTVLAGPISGKSVL 171 Query: 209 VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSE 268 + G G +GL I K++GA +I + + + E A VGA I+P + + EV+ Sbjct: 172 ITGAGPLGLLGIAVAKASGAYPVIVSEPSDFRRELAKKVGADYVINPFE-EDVVKEVMDI 230 Query: 269 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKG 328 GN V E G + + L + G ++G+ P + ++ +++F T G Sbjct: 231 TDGNGVDVFLEFSGAPKALEQGLQAVTPA-GRVSLLGLYPGKVTIDFNNLIIFKALTIYG 289 Query: 329 CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSGQSIRTVLTF 386 G + + + K +LD +ITH F K E FEL+ +G++ + V Sbjct: 290 --ITGRHLWETWYTVSRLLQSGKLNLDPIITHKYKGFDKYEEAFELMRAGKTGKVVFML 346 >3MEQ-A nrPDB Length = 365 Score = 298 bits (763), Expect = 3e-81, Method: Composition-based stats. Identities = 92/368 (25%), Positives = 146/368 (39%), Gaps = 35/368 (9%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAV+ +P +I+E+ + P ++++ I A+G+C TD H +G K P I GH Sbjct: 27 KAAVVRAFGKPLTIDEVPIPQPGPGQIQVAIQASGVCHTDLHAAEGDWPVKPNPPFIPGH 86 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G V ++G GV VK GD+V IP C C C LC TG V Sbjct: 87 EGVGFVSAVGSGVKHVKEGDRVGIPWLYTACGHCRHCLGGWETLCEEQLNTGYSV----- 141 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 F EY V D + V + ++ + C T Y +K Sbjct: 142 ---------------NGGFAEYVVADPNFVGHLPKNIDFNEIAPVLCAGVTVY-KGLKVT 185 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 KPG V+ G+GG+G + ++ G + + +D++ K + A +GAT ++ K Sbjct: 186 DTKPGDWVVISGIGGLGHMAVQYARAMGLN-VAAVDIDDRKLDLARRLGATVTVNAKTVA 244 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 P + + E G G + + AL GT + G+PP L+ M+ Sbjct: 245 DPAAYIRKETDGGAQGVLVTAV-SPKAFEQALGMV-ARGGTVSLNGLPPGDFPLSIFNMV 302 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ- 378 L G T +G + G + + K + I+ F+ + G Sbjct: 303 L-NGVTVRGSIVGTRLDLQESLDFAADGKVKATI------QTGKLEDINAIFDDMRQGNI 355 Query: 379 SIRTVLTF 386 R V+ Sbjct: 356 EGRIVMDL 363 >1F8F-A nrPDB Length = 371 Score = 293 bits (751), Expect = 7e-80, Method: Composition-based stats. Identities = 108/365 (29%), Positives = 176/365 (48%), Gaps = 9/365 (2%) Query: 24 AAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEAT 83 AAV + F ++ +++ P+ EV +K++ATG+C TD V P ++GHE + Sbjct: 9 AAVTPCKGADFELQALKIRQPQGDEVLVKVVATGMCHTDLIVRDQKYPVPLPAVLGHEGS 68 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIR---SDITGRGVLADGTT 140 GI+E+IG VT ++ GD V+ L C +C C + C + +G + Sbjct: 69 GIIEAIGPNVTELQVGDHVV-LSYGYCGKCTQCNTGNPAYCSEFFGRNFSGADSEGNHAL 127 Query: 141 RFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGK 200 +G HF S+F Y + E++ K+ P E + +GCG TG GA + K Sbjct: 128 CTHDQGVVNDHFFAQSSFATYALSRENNTVKVTKDVPIELLGPLGCGIQTGAGACINALK 187 Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 V P S+ V +G G VGLS ++ K GAS II +D+ + + E A +GAT I+ K + Sbjct: 188 VTPASSFVTWGAGAVGLSALLAAKVCGASIIIAVDIVESRLELAKQLGATHVINSK-TQD 246 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYD-PML 319 P++ + E+T V + E G E + + + + G VVG P +D L Sbjct: 247 PVAAI-KEITDGGVNFALESTGSPEILKQGVDALGI-LGKIAVVGAPQLGTTAQFDVNDL 304 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQS 379 L G+T G V G + +P+LV + KF DQL+ F +I++ G + Sbjct: 305 LLGGKTILGVVEGSGSPKKFIPELVRLYQQGKFPFDQLV-KFYAFDEINQAAIDSRKGIT 363 Query: 380 IRTVL 384 ++ ++ Sbjct: 364 LKPII 368 >3GFB-A nrPDB Length = 350 Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats. Identities = 90/357 (25%), Positives = 151/357 (42%), Gaps = 36/357 (10%) Query: 35 SIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS----KFPVIVGHEATGIVESIG 90 + E++V P EV IK+LAT IC TD H+ + + K P I+GHE G V +G Sbjct: 18 ELVEVDVPKPGPGEVLIKVLATSICGTDLHIYEWNEWAQSRIKPPQIMGHEVAGEVVEVG 77 Query: 91 EGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVH 150 GV ++ GD + C +C AC++ ++C + I G + Sbjct: 78 PGVEDLQVGDYISVETHIVCGKCYACKHNRYHVCQNTKIFGVDM---------------- 121 Query: 151 HFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP--GSTCV 208 F Y +V + K PPE L G AV T P G + + Sbjct: 122 ----DGVFAHYAIVPAKNAWKNPKDMPPEYAAL-----QEPLGNAVDTVLAGPIAGRSTL 172 Query: 209 VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSE 268 + G G +GL I K++GA +I + ++ + + A VGA ++P + P+ V+ Sbjct: 173 ITGAGPLGLLGIAVAKASGAYPVIVSEPSEFRRKLAKKVGADYVVNPFE-EDPVKFVMDI 231 Query: 269 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKG 328 G V E G + + L + G ++G+ P + ++ +++F G Sbjct: 232 TDGAGVEVFLEFSGAPKALEQGLKAVTPG-GRVSLLGLFPREVTIDFNNLIIFKALEVHG 290 Query: 329 CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSGQSIRTVL 384 G + + + + K +LD +ITH F K E FEL+ +G++ + V Sbjct: 291 --ITGRHLWETWYTVSSLIQSGKLNLDPIITHKYKGFDKFEEAFELMRAGKTGKVVF 345 >1PL8-A nrPDB Length = 356 Score = 290 bits (741), Expect = 1e-78, Method: Composition-based stats. Identities = 89/364 (24%), Positives = 151/364 (41%), Gaps = 33/364 (9%) Query: 26 VLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHE 81 V+ +E + P EV +++ + GIC +D H + G + K P+++GHE Sbjct: 12 VVHGPGD-LRLENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHE 70 Query: 82 ATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTR 141 A+G VE +G V +KPGD+V C+ NL + Sbjct: 71 ASGTVEKVGSSVKHLKPGDRVAIEPGAPRENDEFCKMGRYNL--------------SPSI 116 Query: 142 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 F C P + + + + K+ D E+ LI S G A + G V Sbjct: 117 FFCATPP-----DDGNLCRFYKHNAAFCYKLPDNVTFEEGALIE-PLSVGIHACRR-GGV 169 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTK 260 G +V G G +G+ ++ K+ GA++++ DL+ + KA +GA + K+S + Sbjct: 170 TLGHKVLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVLQISKESPQ 229 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 I+ + G T E G E I A + GT V+VG+ +T P+L Sbjct: 230 EIARKVEGQLGCKPEVTIECTGA-EASIQAGIYATRSGGTLVLVGL---GSEMTTVPLLH 285 Query: 321 FTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSI 380 R + G + + P ++ +K ++ L+TH P +K E FE G + Sbjct: 286 AAIREVD--IKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGL 343 Query: 381 RTVL 384 + +L Sbjct: 344 KIML 347 >4Z6K-A nrPDB Length = 346 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 93/368 (25%), Positives = 154/368 (41%), Gaps = 37/368 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAVL E Q IEE+++ P E+ +K+ A+G+C TD H ++G K P I GH Sbjct: 2 KAAVLHEFGQSLQIEEVDIPTPGAGEIVVKMQASGVCHTDLHAVEGDWPVKPSPPFIPGH 61 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G++ ++GEGVT VK GD+V + C C C LC +G V Sbjct: 62 EGVGLITAVGEGVTHVKEGDRVGVAWLYSACGHCTHCLGGWETLCESQQNSGYSV----- 116 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 +F EY + + + V I ++ ++ + C T Y +K Sbjct: 117 ---------------NGSFAEYVLANANYVGIIPESVDSIEIAPVLCAGVTVY-KGLKMT 160 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 KPG V+ G+GG+G + + G + + +D++ DK A +GA ++ K+ T Sbjct: 161 DTKPGDWVVISGIGGLGHMAVQYAIAMGLN-VAAVDIDDDKLAFAKKLGAKVTVNAKN-T 218 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 P + E+ G + + AL+ GT V G+PP ++ Sbjct: 219 DPAEYLQKEIGGAH--GALVTAVSAKAFDQALSML-RRGGTLVCNGLPPGDFPVSIF-DT 274 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ- 378 + G T +G + G + + K P + I++ FE + G+ Sbjct: 275 VLNGITIRGSIVGTRLDLQESLDMAAAGKVKA------TVTAEPLENINDIFERMRQGKI 328 Query: 379 SIRTVLTF 386 R V+ + Sbjct: 329 EGRIVIDY 336 >3QE3-A nrPDB Length = 355 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 90/364 (24%), Positives = 156/364 (42%), Gaps = 33/364 (9%) Query: 26 VLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHE 81 V+ +E + P EV +K+ + GIC +D H + G V K P+++GHE Sbjct: 11 VVHGPGD-LRLENYPIPEPGPNEVLLKMHSVGICGSDVHYWQHGRIGDFVVKKPMVLGHE 69 Query: 82 ATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTR 141 A+G V +G V ++PGD+V + C+ NL T Sbjct: 70 ASGTVVKVGSLVRHLQPGDRVAIQPGAPRQTDEFCKIGRYNL--------------SPTI 115 Query: 142 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 F C P + + + + K+ D E+ LI S G A + G V Sbjct: 116 FFCATPP-----DDGNLCRFYKHNANFCYKLPDNVTFEEGALIE-PLSVGIHACRRAG-V 168 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTK 260 G+ +V G G +GL ++ K+ GA++++ DL+ + KA VGA + +S + Sbjct: 169 TLGNKVLVCGAGPIGLVNLLAAKAMGAAQVVVTDLSASRLSKAKEVGADFILEISNESPE 228 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 I++ + + G+ T E G +ET I A + GT V+VG+ +T P++ Sbjct: 229 EIAKKVEGLLGSKPEVTIECTG-VETSIQAGIYATHSGGTLVLVGL---GSEMTSVPLVH 284 Query: 321 FTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSI 380 R + G + + P ++ +K ++ L+TH P +K E FE G + Sbjct: 285 AATREVD--IKGVFRYCNTWPMAISMLASKSVNVKPLVTHRFPLEKALEAFETSKKGLGL 342 Query: 381 RTVL 384 + ++ Sbjct: 343 KVMI 346 >1LLU-A nrPDB Length = 342 Score = 284 bits (726), Expect = 6e-77, Method: Composition-based stats. Identities = 93/366 (25%), Positives = 144/366 (39%), Gaps = 37/366 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAV+ P IEE++V P +V +KI A+G+C TD H +G K P I GH Sbjct: 8 KAAVVHAYGAPLRIEEVKVPLPGPGQVLVKIEASGVCHTDLHAAEGDWPVKPPLPFIPGH 67 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G V ++G GVT VK GD+V IP C C C LC TG V Sbjct: 68 EGVGYVAAVGSGVTRVKEGDRVGIPWLYTACGCCEHCLTGWETLCESQQNTGYSV----- 122 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY + D + V + ++ I C T Y +T Sbjct: 123 ---------------NGGYAEYVLADPNYVGILPKNVEFAEIAPILCAGVTVYKGLKQT- 166 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 +PG + G+GG+G + ++ G + ID++ K E A +GA+ ++ + Sbjct: 167 NARPGQWVAISGIGGLGHVAVQYARAMGL-HVAAIDIDDAKLELARKLGASLTVNARQ-E 224 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 P+ + ++ G G + + A+ GT +VG+PP + Sbjct: 225 DPVEAIQRDI-GGAHGVLVTAVSN-SAFGQAIGMA-RRGGTIALVGLPPGDFPTPIF-DV 280 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ- 378 + G G + G + E L K H I++ + + +GQ Sbjct: 281 VLKGLHIAGSIVGTRADLQEALDFAGEGLVKATI------HPGKLDDINQILDQMRAGQI 334 Query: 379 SIRTVL 384 R VL Sbjct: 335 EGRIVL 340 >3S2F-A nrPDB Length = 340 Score = 279 bits (714), Expect = 1e-75, Method: Composition-based stats. Identities = 93/368 (25%), Positives = 149/368 (40%), Gaps = 37/368 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIVGH 80 KAAV+ P +I+E+ V P +V++KI A+G+C TD H G K P I GH Sbjct: 4 KAAVVRAFGAPLTIDEVPVPQPGPGQVQVKIEASGVCHTDLHAADGDWPVKPTLPFIPGH 63 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G V ++G GV+ VK GD+V +P C C C LC + TG V Sbjct: 64 EGVGYVSAVGSGVSRVKEGDRVGVPWLYSACGYCEHCLQGWETLCEKQQNTGYSV----- 118 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + EY V D + V + D ++ I C T Y +K Sbjct: 119 ---------------NGGYGEYVVADPNYVGLLPDKVGFVEIAPILCAGVTVY-KGLKVT 162 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 +PG V+ G+GG+G + ++ G R+ +D++ K A +GA ++ +D T Sbjct: 163 DTRPGQWVVISGIGGLGHVAVQYARAMGL-RVAAVDIDDAKLNLARRLGAEVAVNARD-T 220 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 P + + E+ G + + A+ GT + G+PP + Sbjct: 221 DPAAWLQKEIGGAH--GVLVTAVSPKAFSQAIGMV-RRGGTIALNGLPPGDFGTPIF-DV 276 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ- 378 + G T +G + G + A D+ ++ +++ F L G+ Sbjct: 277 VLKGITIRGSIVGTRSDLQESLDF-----AAHGDVKATVS-TAKLDDVNDVFGRLREGKV 330 Query: 379 SIRTVLTF 386 R VL F Sbjct: 331 EGRVVLDF 338 >2EER-A nrPDB Length = 347 Score = 279 bits (714), Expect = 1e-75, Method: Composition-based stats. Identities = 91/375 (24%), Positives = 156/375 (41%), Gaps = 42/375 (11%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS---------K 73 +A L E +P +E+I + PK +V IKI A G+C +D H+ +G + K Sbjct: 2 RAMRLVEIGKPLKLEDIPIPKPKGSQVLIKIEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 PV +GHE G +E +G+ V GD V C CR + +LC G Sbjct: 62 LPVTLGHEIAGRIEEVGDEVVGYSKGDLVAVNPWEGEGNCYYCRIGEEHLCDS--PRWLG 119 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDE-SSVAKIDDAAPPEKVCLIGCGFSTGY 192 + DG + EY +V + K+ + E + C T Y Sbjct: 120 INYDGA------------------YAEYVLVPHYKYLYKLRRLSAVE-AAPLTCSGVTTY 160 Query: 193 GAAVKTGKVKPGSTCVVFGLGG-VGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 AV+ + P T VV G GG +G I K+ + IIG+D+ ++ E A GA Sbjct: 161 R-AVRKASLDPSKTLVVIGAGGGLGTMAIQIAKAVSGATIIGVDVREEALEAAKRAGADY 219 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 I+ S P+SE+ G + + + E + G V+VG+ A Sbjct: 220 VINA-SSQDPVSEIRRITQGKGADAVID-LNNSEKTLSIYPYVLAKQGKYVMVGL-FGAD 276 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 + + P++ + G + G ++ D +++ A K + ++T + ++ +E Sbjct: 277 LKYHAPLITLNEVQFIGSLVG---NQSDFLGIMSLAEAGK--VKPMVTKTMKLEEANEAI 331 Query: 372 ELLNSGQSI-RTVLT 385 + L + +++ R VL Sbjct: 332 DNLENFKAVGRQVLV 346 >2DQ4-A nrPDB Length = 343 Score = 279 bits (713), Expect = 2e-75, Method: Composition-based stats. Identities = 88/370 (23%), Positives = 148/370 (40%), Gaps = 38/370 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK----FPVIV 78 +A ++ ++ + V P E+ +++ A IC TD H+ K ++ P++ Sbjct: 2 RALAKLAPEEGLTLVDRPVPEPGPGEILVRVEAASICGTDLHIWKWDAWARGRIRPPLVT 61 Query: 79 GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 GHE +G+VE++G GV + GD V C C ACR + ++C+ + I G Sbjct: 62 GHEFSGVVEAVGPGVRRPQVGDHVSLESHIVCHACPACRTGNYHVCLNTQILGV------ 115 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVC---LIGCGFSTGYGAA 195 F EY VV + P E G T Y Sbjct: 116 --------------DRDGGFAEYVVVPAENAWVNPKDLPFEVAAILEPFGNAVHTVY--- 158 Query: 196 VKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISP 255 G G + ++ G G +GL M +++GA I+ D N + A A ++P Sbjct: 159 --AGSGVSGKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPY-ADRLVNP 215 Query: 256 KDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTY 315 + + EV+ +TG+ V E G+ + L + G + ++G+P Sbjct: 216 LEED--LLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALIPG-GEARILGIPSDPIRFDL 272 Query: 316 DPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLN 375 L+ G T G G + + + + DL L+TH LP + E F LL Sbjct: 273 AGELVMRGITAFG--IAGRRLWQTWMQGTALVYSGRVDLSPLLTHRLPLSRYREAFGLLA 330 Query: 376 SGQSIRTVLT 385 SGQ+++ +L Sbjct: 331 SGQAVKVILD 340 >4CPD-A nrPDB Length = 347 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 94/365 (25%), Positives = 159/365 (43%), Gaps = 27/365 (7%) Query: 25 AVLWEQKQPFSIEEIEVAPPK-TKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEAT 83 AV++E K+ +++E+ + + +++ GIC +D H+ G + ++GHE Sbjct: 3 AVVFENKERVAVKEVNAPRLQHPLDALVRVHLAGICGSDLHLYHGKIPVLPGSVLGHEFV 62 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFT 143 G VE++GEG+ ++PGD V+ F C C CR NLC R + G G + Sbjct: 63 GQVEAVGEGIQDLQPGDWVVGPFHIACGTCPYCRRHQYNLCERGGVYGYGPMFGNL---- 118 Query: 144 CKGKPVHHFMNTSTFTEYTVVDESSV--AKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 E V S+V K+ PE+ G ST YG ++ G++ Sbjct: 119 -----------QGAQAEILRVPFSNVNLRKLPPNLSPERAIFAGDILSTAYGGLIQ-GQL 166 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP 261 +PG + V G G VGL I + GAS+I+ ID ++ E+A ++GA I+ + P Sbjct: 167 RPGDSVAVIGAGPVGLMAIEVAQVLGASKILAIDRIPERLERAASLGAIP-INA-EQENP 224 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLF 321 + V SE E +G T+ AL G VGV P L Sbjct: 225 VRRVRSETNDEGPDLVLEAVGGAATLSLALEMV-RPGGRVSAVGV----DNAPSFPFPLA 279 Query: 322 TGRTWKGCVFGGLKSRDDVPKLV-TEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSI 380 +G GL + V + + +++++H LP ++ G+EL + +++ Sbjct: 280 SGLVKDLTFRIGLANVHLYIDAVLALLASGRLQPERIVSHYLPLEEAPRGYELFDRKEAL 339 Query: 381 RTVLT 385 + +L Sbjct: 340 KVLLV 344 >6N7L-A nrPDB Length = 353 Score = 270 bits (690), Expect = 7e-73, Method: Composition-based stats. Identities = 94/367 (25%), Positives = 142/367 (38%), Gaps = 38/367 (10%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKF--PVIVGH 80 KAAV+ +P I+E+ V P EV +K++A G+C TD H + G +K P+I GH Sbjct: 15 KAAVVQGYGEPLKIQEVPVREPGRYEVLVKVMACGVCHTDLHAVDGDWPAKPKMPLIPGH 74 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E GIV + G VK GD V +P C C+ C LC G V Sbjct: 75 EGVGIVVACGPDA-MVKEGDAVGVPWLYSACGCCDYCITGWETLCEAQQNGGYSV----- 128 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 F EY + D V + ++ I C T Y +T Sbjct: 129 ---------------DGGFAEYVIADSRYVGHLKSNVNFLEIAPILCAGVTVYKGLKET- 172 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 + KPG + G+GG+G + K+ G + ID+ DK E A +GA ++ K +T Sbjct: 173 ETKPGEWVAISGIGGLGHVAVQYAKAMGM-HVAAIDVADDKLELAKKLGADLTVNAK-TT 230 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 P + + E+ G + + GT + G+PP + L Sbjct: 231 DPGTYLHKEVGGMH--GALITAVSPIAFKQGID-VLRRKGTIALNGLPPGSFELPIF-ET 286 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ- 378 + T +G + G K + E L K + I++ F+ + GQ Sbjct: 287 VLKRITVRGSIVGTRKDLQEALDFANEGLVKATVTSA------KLEDINDVFDKMKKGQI 340 Query: 379 SIRTVLT 385 R VL Sbjct: 341 DGRIVLD 347 >1E3J-A nrPDB Length = 352 Score = 269 bits (687), Expect = 2e-72, Method: Composition-based stats. Identities = 83/371 (22%), Positives = 149/371 (40%), Gaps = 38/371 (10%) Query: 24 AAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVG 79 +AVL++Q +E+ + PK EV +++ GIC +D H + + K P+++G Sbjct: 7 SAVLYKQND-LRLEQRPIPEPKEDEVLLQMAYVGICGSDVHYYEHGRIADFIVKDPMVIG 65 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 HEA+G V +G+ V +K GD+V CR C C+ NLC Sbjct: 66 HEASGTVVKVGKNVKHLKKGDRVAVEPGVPCRRCQFCKEGKYNLCPDLTFCATPPD---- 121 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 Y V K+ D E+ L+ S G A + G Sbjct: 122 ---------------DGNLARYYVHAADFCHKLPDNVSLEEGALLE-PLSVGVHACRRAG 165 Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS---PK 256 V+ G+T +V G G +GL ++ K+ GA ++ + + E A GA + K Sbjct: 166 -VQLGTTVLVIGAGPIGLVSVLAAKAYGAF-VVCTARSPRRLEVAKNCGADVTLVVDPAK 223 Query: 257 DSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYD 316 + I E + G+ T + G+ E I + GT ++VG+ + Sbjct: 224 EEESSIIERIRSAIGDLPNVTIDCSGN-EKCITIGINITRTGGTLMLVGM---GSQMVTV 279 Query: 317 PMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 P++ R + + +D P + + + ++ QL+TH ++ + FE Sbjct: 280 PLVNACAREID--IKSVFRYCNDYPIALEMVASGRCNVKQLVTHSFKLEQTVDAFEAARK 337 Query: 377 G--QSIRTVLT 385 +I+ +++ Sbjct: 338 KADNTIKVMIS 348 >5KIA-A nrPDB Length = 351 Score = 265 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 88/369 (23%), Positives = 148/369 (40%), Gaps = 35/369 (9%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS----KFPVIV 78 KA E+ ++ ++ +V IKI T IC TD H+ K + P+ V Sbjct: 10 KALAKLERGPGLTLTRVKKPEVGHNDVLIKIRRTAICGTDIHIWKWDDWAQKTIPVPMHV 69 Query: 79 GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 GHE G + +G+ V GD+V C C CR +LC + G GV +G Sbjct: 70 GHEYVGEIVEMGQEVRGFSIGDRVSGEGHITCGFCRNCRAGRRHLCRNTV--GVGVNREG 127 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 F EY + + KI + I F A+ Sbjct: 128 A------------------FAEYLAIPAFNAFKIPPEISDDLAA-IFDPFGNATHTALSF 168 Query: 199 GKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKD 257 V G ++ G G +G+ + K GA ++ D+N + + A +GAT ++ ++ Sbjct: 169 NLV--GEDVLITGAGPIGVMAVAIAKHVGARNVVITDINDYRLDLARRMGATRAVNVSRE 226 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP 317 S + + L G +VG E+ G L S + G ++G+PP+ + ++ Sbjct: 227 SLRDVMADLHMTEGFDVG--LEMSGVPSAFTSLLESMNHG-GKVALLGIPPAQTAIDWN- 282 Query: 318 MLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG 377 ++F G KG G + + K+V + DL +ITH +GF + SG Sbjct: 283 QVIFKGLEIKGIY--GREMFETWYKMVAMLQSG-LDLSPIITHRFAVDDYEKGFAAMLSG 339 Query: 378 QSIRTVLTF 386 +S + +L + Sbjct: 340 ESGKVILDW 348 >5YLN-A nrPDB Length = 356 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 94/367 (25%), Positives = 162/367 (44%), Gaps = 31/367 (8%) Query: 25 AVLWEQKQPFSIEEIEVAPP-KTKEVRIKILATGICRTDDHVIKGTMVS-KFPVIVGHEA 82 A + + S +++ K + ++I+ T IC TD H+IKG + + + I+GHE Sbjct: 7 AYTYVKPGLASFVDVDKPVIRKPTDAIVRIVKTTICGTDLHIIKGDVPTCQSGTILGHEG 66 Query: 83 TGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRF 142 GIVE +GEGV+ K GDKV+ + C +C C+ C G L DG Sbjct: 67 IGIVEEVGEGVSNFKKGDKVLISCVCACGKCYYCKKGIYAHCEDEGGWIFGHLIDGMQ-- 124 Query: 143 TCKGKPVHHFMNTSTFTEYTVVD--ESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGK 200 EY V ++++ + E + ++ TGY V GK Sbjct: 125 ----------------AEYLRVPHADNTLYHTPEDLSDEALVMLSDILPTGYEIGVLKGK 168 Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 V+PG + + G G VGL+ ++ + +++I +DL+ ++ E A++ GAT ++ D K Sbjct: 169 VEPGCSVAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGATHKVNSSDPEK 228 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 I E+ G V E +G T D GT GV K + +D L Sbjct: 229 AIKEIYDLTDGRGVDVAIEAVGIPATF-DFCQKIIGVDGTVANCGV--HGKPVEFDLDKL 285 Query: 321 FTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG--- 377 + V GL S + P+L+ + K + ++L+TH +I + +E+ + Sbjct: 286 WIRNI---NVTTGLVSTNTTPQLLKALESHKIEPEKLVTHYFKLSEIEKAYEVFSKAADH 342 Query: 378 QSIRTVL 384 +I+ ++ Sbjct: 343 HAIKVII 349 >1H2B-A nrPDB Length = 359 Score = 257 bits (656), Expect = 7e-69, Method: Composition-based stats. Identities = 86/377 (22%), Positives = 152/377 (40%), Gaps = 41/377 (10%) Query: 19 VIKCKAAVLWEQKQPFSIEEIEVAP-PKTKEVRIKILATGICRTDDHVIKGTM----VSK 73 V + KAA L E +P IE+++ +V ++I G+C TD H+++G K Sbjct: 13 VERLKAARLHEYNKPLRIEDVDYPRLEGRFDVIVRIAGAGVCHTDLHLVQGMWHELLQPK 72 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 P +GHE G +E + EGV ++ GD VI C ACR + C + G Sbjct: 73 LPYTLGHENVGYIEEVAEGVEGLEKGDPVILHPAVTDGTCLACRAGEDMHCENLEFPGLN 132 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKV---CLIGCGFST 190 + F E+ SV K+ EK+ + T Sbjct: 133 I--------------------DGGFAEFMRTSHRSVIKLPKDISREKLVEMAPLADAGIT 172 Query: 191 GYGAAVKTGK-VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGA 249 Y A K + + PG+ + G+GG+G + K + +I +D+ ++K + A +GA Sbjct: 173 AYRAVKKAARTLYPGAYVAIVGVGGLGHIAVQLLKVMTPATVIALDVKEEKLKLAERLGA 232 Query: 250 TECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPS 309 + + P+ +V+ G V + +G T +D G ++VG Sbjct: 233 DHVVDAR--RDPVKQVMELTRGRGVNVAMDFVGSQAT-VDYTPYLLGRMGRLIIVGYGGE 289 Query: 310 AKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISE 369 + T ++ + +++G + G + LVT L K ++ + +I++ Sbjct: 290 LRFPTIR--VISSEVSFEGSLVGNYVELHE---LVTLALQGKVRVE---VDIHKLDEIND 341 Query: 370 GFELLNSGQSI-RTVLT 385 E L G+ + R VL Sbjct: 342 VLERLEKGEVLGRAVLI 358 >4EEZ-A nrPDB Length = 348 Score = 256 bits (654), Expect = 1e-68, Method: Composition-based stats. Identities = 92/367 (25%), Positives = 149/367 (40%), Gaps = 33/367 (8%) Query: 23 KAAVLWEQKQPFS-IEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHE 81 KAAV+ ++ + E E+ K E + + G+C TD HV G +K ++GHE Sbjct: 2 KAAVVRHNPDGYADLVEKELRAIKPNEALLDMEYCGVCHTDLHVAAGDFGNKAGTVLGHE 61 Query: 82 ATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTT 140 GIV+ IG V++++ GD+V + F C C C + + C G V Sbjct: 62 GIGIVKEIGADVSSLQVGDRVSVAWFFEGCGHCEYCVSGNETFCREVKNAGYSV------ 115 Query: 141 RFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGK 200 E +V K+ D P + I C T Y A+K Sbjct: 116 --------------DGGMAEEAIVVADYAVKVPDGLDPIEASSITCAGVTTY-KAIKVSG 160 Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 VKPG V+FG GG+G I K+ +++I +D+N+DK A +GA I+ D Sbjct: 161 VKPGDWQVIFGAGGLGNLAIQYAKNVFGAKVIAVDINQDKLNLAKKIGADVTINSGDVN- 219 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 P+ E+ G V A+AS G V V VP + L+ P ++ Sbjct: 220 PVDEIKKITGGLGVQSAIVCAVARIAFEQAVASLKP-MGKMVAVAVPNTEMTLSV-PTVV 277 Query: 321 FTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ-S 379 F G G + G + + E + ++ ++I++ + + +G+ Sbjct: 278 FDGVEVAGSLVGTRLDLAEAFQFGAEG-----KVKPIVATR-KLEEINDIIDEMKAGKIE 331 Query: 380 IRTVLTF 386 R V+ F Sbjct: 332 GRMVIDF 338 >1R37-A nrPDB Length = 347 Score = 252 bits (644), Expect = 2e-67, Method: Composition-based stats. Identities = 89/375 (23%), Positives = 153/375 (40%), Gaps = 42/375 (11%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS---------K 73 +A L E +P S++EI V PK +V IK+ A G+C +D H+ +G + K Sbjct: 2 RAVRLVEIGKPLSLQEIGVPKPKGPQVLIKVEAAGVCHSDVHMRQGRFGNLRIVEDLGVK 61 Query: 74 FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRG 133 PV +GHE G +E +G+ V GD V C CR + +LC G Sbjct: 62 LPVTLGHEIAGKIEEVGDEVVGYSKGDLVAVNPWQGEGNCYYCRIGEEHLCDS--PRWLG 119 Query: 134 VLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDE-SSVAKIDDAAPPEKVCLIGCGFSTGY 192 + DG + EY +V + K+ E + C T Y Sbjct: 120 INFDGA------------------YAEYVIVPHYKYMYKLRRLNAVE-AAPLTCSGITTY 160 Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGL-SVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 AV+ + P T +V G GG + K+ + IIG+D+ ++ E A GA Sbjct: 161 R-AVRKASLDPTKTLLVVGAGGGLGTMAVQIAKAVSGATIIGVDVREEAVEAAKRAGADY 219 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311 I+ P++E+ V + + + E + G V+VG+ A Sbjct: 220 VINA-SMQDPLAEIRRITESKGVDAVID-LNNSEKTLSVYPKALAKQGKYVMVGL-FGAD 276 Query: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371 + + P++ + + G + G ++ D ++ A K + +IT + ++ +E Sbjct: 277 LHYHAPLITLSEIQFVGSLVG---NQSDFLGIMRLAEAGK--VKPMITKTMKLEEANEAI 331 Query: 372 ELLNSGQSI-RTVLT 385 + L + ++I R VL Sbjct: 332 DNLENFKAIGRQVLI 346 >5ENV-A nrPDB Length = 347 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 85/360 (23%), Positives = 134/360 (37%), Gaps = 34/360 (9%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM--VSKFPVIVGH 80 K + +E ++I V PK E+ I + +G+C TD H G K P++ GH Sbjct: 7 KGVIFYESHGKLEYKDIPVPKPKANELLINVKYSGVCHTDLHAWHGDWPLPVKLPLVGGH 66 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G+V +GE V K GD I C C C + + C +D++G Sbjct: 67 EGAGVVVGMGENVKGWKIGDYAGIKWLNGSCMACEYCELGNESNCPHADLSG-------- 118 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + + +F +Y D A I +V I C T Y A+K+ Sbjct: 119 ------------YTHDGSFQQYATADAVQAAHIPQGTDLAQVAPILCAGITVY-KALKSA 165 Query: 200 KVKPGSTCVVFG-LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 + G + G GG+G + K+ G R++GID + K E ++G I Sbjct: 166 NLMAGHWVAISGAAGGLGSLAVQYAKAMG-YRVLGIDGGEGKEELFRSIGGEVFIDFTKE 224 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 + VL G G + E I+A GT+V+VG+P AK + Sbjct: 225 KDIVGAVLKATDGGAHGVIN--VSVSEAAIEASTRYVRANGTTVLVGMPAGAKCCSDVFN 282 Query: 319 LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 378 + + G G + L K + V+ + E +E + GQ Sbjct: 283 QVVKSISIVGSYVGNRADTREALDFFARGLVK----SPI--KVVGLSTLPEIYEKMEKGQ 336 >5VM2-A nrPDB Length = 347 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 84/351 (23%), Positives = 133/351 (37%), Gaps = 33/351 (9%) Query: 27 LWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT--MVSKFP---VIVGHE 81 + + I E+ PK EV IK+ GIC +D H + + K P + +GHE Sbjct: 7 ILQVPGTMKIISAEIPVPKEDEVLIKVEYVGICGSDVHGFESGPFIPPKDPNQEIGLGHE 66 Query: 82 ATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTR 141 G V ++G V KPGD+V C C C N+C D G Sbjct: 67 CAGTVVAVGSRVRKFKPGDRVNIEPGVPCGHCRYCLEGKYNICPDVDFMATQPNYRGA-- 124 Query: 142 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 T Y ES K+ D + L+ + G AA+ V Sbjct: 125 ----------------LTHYLCHPESFTYKLPDNMDTMEGTLVEPA-AVGMHAAM-LADV 166 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP 261 KPG ++ G G +GL + CK GA+ I +D+ + + A +GAT I+ Sbjct: 167 KPGKKIIILGAGCIGLMTLQACKCLGATEIAVVDVLEKRLAMAEQLGATVVINGAK-EDT 225 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLF 321 I+ FE G T+ A M G ++VG P A + + L Sbjct: 226 IARCQQFTEDMGADIVFETAGSAVTVKQA-PYLVMRGGKIMIVGTVPGASAINF----LK 280 Query: 322 TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFE 372 R + + + P + + +FD+ ++TH+ ++ + + FE Sbjct: 281 INREV--TIQTVFRYANRYPVTIEAISSGRFDVKSMVTHIYDYRDVQQAFE 329 >4OH1-A nrPDB Length = 351 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 81/360 (22%), Positives = 142/360 (39%), Gaps = 44/360 (12%) Query: 35 SIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-------SKFPVIVGHEATGIVE 87 + E + PK +E+RIK++ IC +D H++ G + S P+ GHE +G+++ Sbjct: 22 DMMEAPMPEPKDEEIRIKVVYASICGSDTHILTGNLGEMESTTRSMLPMSFGHELSGVID 81 Query: 88 SIGEGVTT--VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCK 145 +G K G KV+ + C C CR NLC G +G Sbjct: 82 KVGSTAEKMGFKVGQKVVANYAKYCGCCENCREGKVNLCSN-----MGYRMNG------- 129 Query: 146 GKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGS 205 F+EY V S + I D A + L+ T ++ + K+ G Sbjct: 130 ------------FSEYAVYHMSQIFPIPDDADLKDYALVEP--LTVALSSAEQAKISYGK 175 Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEV 265 + + G GG+G+ ++ + AGAS I D+ +K E A+ GA ++ + + ++E Sbjct: 176 SVAIMGAGGLGMMLVQLARLAGASTITVFDIVPEKLELALENGADYALNSAE--EGVAER 233 Query: 266 LSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRT 325 E+ G E G L G +V + +L P+ L + Sbjct: 234 AIELAGGRYDCVLEGTGATAAAKLGLQ-LLARDGDAVYFAMYGKDPIL---PVNLQSDLY 289 Query: 326 WKG-CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVL 384 W + G ++ PK + + + D ++I + FE L S + + V+ Sbjct: 290 WDQKHIHGMIQGAWQFPKSIR--MIPRMDFSKIIQKEHTLTNYKQAFEDLYSKKYAKIVI 347 >1YKF-A nrPDB Length = 352 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 92/359 (25%), Positives = 153/359 (42%), Gaps = 33/359 (9%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E E P + ++ LA C +D H V +G + + +I+GHEA G V +G V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 KPGD+V+ P P R R + G+LA +F+ + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH--------SGGMLA--GWKFSN--------VKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F E+ V+++ ++A + P E +I +TG+ A + ++ G+T V G+G Sbjct: 118 GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIELGATVAVLGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 VGL + G K GA RII + + A GAT+ ++ KD S++++ G Sbjct: 177 PVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIE-SQIMNLTEGKG 235 Query: 274 VGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTG---RTWKGCV 330 V G+ + M A+ GT V ++L + G +T KG + Sbjct: 236 VDAAIIAGGNADIMATAVKIVKPG-GTIANVNYFGEGEVLPVPRLEWGCGMAHKTIKGGL 294 Query: 331 FGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNS--GQSIRTVLTF 386 G + R + +L+ K+ D +L+THV F I + F L+ I+ V+ Sbjct: 295 CPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPVVIL 351 >3FSR-A nrPDB Length = 352 Score = 243 bits (619), Expect = 1e-64, Method: Composition-based stats. Identities = 93/364 (25%), Positives = 153/364 (42%), Gaps = 43/364 (11%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E E P + ++ LA C +D H V +G + + +I+GHEA G V +G V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 KPGD+V+ P P R R + G+LA +F+ + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH--------SGGMLA--GWKFSN--------VKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F E+ V+++ ++A + P E +I +TG+ A + ++ GS+ VV G+G Sbjct: 118 GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELADIQMGSSVVVIGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 VGL I G K GA RIIG+ E A GAT+ ++ K+ + +V+ G Sbjct: 177 AVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNG-HIVDQVMKLTNGKG 235 Query: 274 VGYTFEVIGHLETMIDALASCHMN--------YGTSVVVGVPPSAKMLTYDPMLLFTGRT 325 V G ET+ A++ +G+ + +P +T Sbjct: 236 VDRVIMAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCG------MAHKT 289 Query: 326 WKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNS--GQSIRT 382 KG + G + R + +L+ K+ D +L+THV F I + F L+ I+ Sbjct: 290 IKGGLCPGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKP 347 Query: 383 VLTF 386 V+ Sbjct: 348 VVIL 351 >3FPC-A nrPDB Length = 352 Score = 242 bits (618), Expect = 2e-64, Method: Composition-based stats. Identities = 87/358 (24%), Positives = 147/358 (41%), Gaps = 31/358 (8%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E E P + ++ LA C +D H V +G + + +I+GHEA G V +G V Sbjct: 16 EKEKPAPGPFDAIVRPLAVAPCTSDIHTVFEGAIGERHNMILGHEAVGEVVEVGSEVKDF 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 KPGD+V+ P P R R + G+LA +F+ + Sbjct: 76 KPGDRVVVPAITPDWRTSEVQRGYHQH--------SGGMLA--GWKFSN--------VKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F E+ V+++ ++A + P E +I +TG+ A + +K G T V G+G Sbjct: 118 GVFGEFFHVNDADMNLAHLPKEIPLEAAVMIPDMMTTGFHGA-ELANIKLGDTVCVIGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 VGL + G GA RI + K + A+ GAT+ I+ K+ + ++L G Sbjct: 177 PVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNG-DIVEQILKATDGKG 235 Query: 274 VGYTFEVIGHLETMIDALASCHMNY--GTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVF 331 V G + T A+ G +G + + + + + G + Sbjct: 236 VDKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNIDIPRSEWGVGMGHKHIHGGLC 295 Query: 332 GGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNS--GQSIRTVLTF 386 G + R + +L+ K+ D +L+THV F I + F L+ I+ V+ Sbjct: 296 PGGRLR--MERLIDLVFYKRVDPSKLVTHVFRGFDNIEKAFMLMKDKPKDLIKPVVIL 351 >1UUF-A nrPDB Length = 369 Score = 239 bits (611), Expect = 1e-63, Method: Composition-based stats. Identities = 77/362 (21%), Positives = 137/362 (37%), Gaps = 30/362 (8%) Query: 20 IKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-FPVIV 78 +K KA + KQP +I P +V+I+I G+C +D H ++ +P + Sbjct: 21 LKIKAVGAYSAKQPLEPMDITRREPGPNDVKIEIAYCGVCHSDLHQVRSEWAGTVYPCVP 80 Query: 79 GHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 GHE G V ++G+ V PGD V + + C+ C C + N C T D Sbjct: 81 GHEIVGRVVAVGDQVEKYAPGDLVGVGCIVDSCKHCEECEDGLENYCDHMTGTYNSPTPD 140 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKID-DAAPPEKVCLIGCGFSTGYGAAV 196 +++ VV E V +I V + C T Y Sbjct: 141 EPG------------HTLGGYSQQIVVHERYVLRIRHPQEQLAAVAPLLCAGITTYSPLR 188 Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK 256 + PG V G+GG+G I + GA ++ ++ K E A A+GA E ++ + Sbjct: 189 H-WQAGPGKKVGVVGIGGLGHMGIKLAHAMGA-HVVAFTTSEAKREAAKALGADEVVNSR 246 Query: 257 DSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYD 316 ++ + + + S + + + D + GT +VG P + Sbjct: 247 NADEMAAHLKSF------DFILNTVAAPHNLDD-FTTLLKRDGTMTLVGAPATPHKSPEV 299 Query: 317 PMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 L+ R G + GG+ ++ E + + ++ +I+E +E + Sbjct: 300 FNLIMKRRAIAGSMIGGIPETQEMLDFCAEH----GIVADI--EMIRADQINEAYERMLR 353 Query: 377 GQ 378 G Sbjct: 354 GD 355 >4ILK-A nrPDB Length = 359 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 85/367 (23%), Positives = 151/367 (41%), Gaps = 37/367 (10%) Query: 25 AVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIVGHEAT 83 ++L E+ SI E E+ P EVR+K+ GIC +D H+ +G +K+P ++GHE Sbjct: 23 SILIEKPNQLSIIEREIPTPSAGEVRVKVKLAGICGSDSHIYRGHNPFAKYPRVIGHEFF 82 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFT 143 G+++++GEGV + + G++V + C C C N+C + G Sbjct: 83 GVIDAVGEGVESARVGERVAVDPVVSCGHCYPCSIGKPNVCTTLAVLGV----------- 131 Query: 144 CKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP 203 F+EY VV + KI +A + +I T G+ Sbjct: 132 ---------HADGGFSEYAVVPAKNAWKIPEAVADQYAVMIEP--FTIAANVTGHGQPTE 180 Query: 204 GSTCVVFGLGGVGLSVIMGCK-SAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 T +V+G G +GL+++ K +I D ++ EKA GA I+ +S P+ Sbjct: 181 NDTVLVYGAGPIGLTIVQVLKGVYNVKNVIVADRIDERLEKAKESGADWAIN--NSQTPL 238 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFT 322 E +E G + H + +A+ V++G + + Sbjct: 239 GESFAEK-GIKPTLIIDAACHPSILKEAVTLASPA-ARIVLMGFSSEPSEV------IQQ 290 Query: 323 GRTWKG-CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFEL--LNSGQS 379 G T K +F + + P ++ ++LITH F+ +++ L L+ Sbjct: 291 GITGKELSIFSSRLNANKFPVVIDWLSKGLIKPEKLITHTFDFQHVADAISLFELDQKHC 350 Query: 380 IRTVLTF 386 + +LTF Sbjct: 351 CKVLLTF 357 >5H82-A nrPDB Length = 389 Score = 238 bits (607), Expect = 3e-63, Method: Composition-based stats. Identities = 79/336 (23%), Positives = 127/336 (37%), Gaps = 16/336 (4%) Query: 45 KTKEVRIKILATGICRTDDHVIKGTMVS-KFPVIVGHEATGIVESIGEGVTTVKPGDKV- 102 +V+ K+L G+C D K T + K+P + GHE GIV IG V K GDKV Sbjct: 52 GEHDVQFKVLYCGLCDWDVITTKNTYGTTKYPFVPGHEIMGIVTEIGNKVKKFKVGDKVG 111 Query: 103 IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYT 162 + F+ C +C C C + T +D ++ Sbjct: 112 VGNFIGSCGKCERCNEGLEPYCPKVIYTDGTAFSDENNTVYGDVSGDGEDRIYGGYSNIM 171 Query: 163 VVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMG 222 V +E V + + P I CG Y G KPG + V G G +G + Sbjct: 172 VANEYVVFRWPENLPLAAGVPILCGGIVPYSPMRHFGLDKPGLSIGVVGFGRIGKLAVKF 231 Query: 223 CKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIG 282 K+ GA+ + K E G + K+ P +E T + + F+ + Sbjct: 232 AKAFGANVTVISTSISKKQEAIEKYGVDRFLISKE---PEEMKAAESTLDGI---FDCVP 285 Query: 283 HLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPK 342 + + L + GT V++GV A L P LL R + G + G +K ++ Sbjct: 286 SVHPLH-PLLNLLKFEGTFVMLGVAVEAYELPVSP-LLMGRRKFVGSISGTMKETQEML- 342 Query: 343 LVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 378 +F AK + + ++P ++ E + G Sbjct: 343 ---DFAAKHNIVSDI--ELIPMDYVNTALERIAKGN 373 >5YAT-A nrPDB Length = 350 Score = 237 bits (604), Expect = 8e-63, Method: Composition-based stats. Identities = 86/359 (23%), Positives = 145/359 (40%), Gaps = 34/359 (9%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV--SKFPVIVGH 80 KA + P ++I V PK+ E+ I + +G+C TD H KG +K P++ GH Sbjct: 10 KAVIFETNGGPLEYKDIPVPKPKSNELLINVKYSGVCHTDLHAWKGDWPLDNKLPLVGGH 69 Query: 81 EATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 E G+V + GE VT + GD I C C C + C ++D++G Sbjct: 70 EGAGVVVAYGENVTGWEIGDYAGIKWLNGSCLNCEYCIQGAESSCAKADLSG-------- 121 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 F + +F +Y D + A+I A +V I C T Y A+KT Sbjct: 122 ------------FTHDGSFQQYATADATQAARIPKEADLAEVAPILCAGITVY-KALKTA 168 Query: 200 KVKPGSTCVV-FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 ++ G + GG+G + K+ G R++GID DK E ++GA + + Sbjct: 169 DLRIGQWVAISGAGGGLGSLAVQYAKALGL-RVLGIDGGADKGEFVKSLGAEVFVDFTKT 227 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 ++EV G V + ++ G V+VG+P A + + Sbjct: 228 KDVVAEVQKLTNG-GPHGVINVSVSPHAINQSVQYV-RTLGKVVLVGLPSGAVVNSDVFW 285 Query: 319 LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG 377 + KG G + + L T L K ++I ++++ +E + +G Sbjct: 286 HVLKSIEIKGSYVGNREDSAEAIDLFTRGLVKA--PIKIIG----LSELAKVYEQMEAG 338 >3FPL-A nrPDB Length = 351 Score = 233 bits (595), Expect = 7e-62, Method: Composition-based stats. Identities = 87/352 (24%), Positives = 144/352 (40%), Gaps = 31/352 (8%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEG 92 E E + + ++ LA C +D H V +G + + +I+GHEA G V +G Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 93 VTTVKPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHH 151 V KPGD+VI P P R + + G + Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEVQAGFQQH-----------------SNGMLAGWKFSN 114 Query: 152 FMNTSTFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 209 F F EY V+++ ++A + P E +I +TG+ A + ++ G+T V Sbjct: 115 F-KDGVFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIELGATVAV 172 Query: 210 FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEM 269 G+G VGL + G K GA RII + + A GAT+ ++ KD S++++ Sbjct: 173 LGIGPVGLMAVAGAKLRGAGRIIAVGSRPVCVDAAKYYGATDIVNYKDGPIE-SQIMNLT 231 Query: 270 TGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTG---RTW 326 G V G+ + M A+ GT V ++L + G +T Sbjct: 232 EGKGVDAAIIAGGNADIMATAVKIVKPG-GTIANVNYFGEGEVLPVPRLEWGCGMAHKTI 290 Query: 327 KGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSG 377 KG + G + R ++ + + + + DL +L+THV F I E L+ Sbjct: 291 KGGLCPGGRLRAEMLRDMVVY--NRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 >3TWO-A nrPDB Length = 348 Score = 233 bits (595), Expect = 8e-62, Method: Composition-based stats. Identities = 86/365 (23%), Positives = 145/365 (39%), Gaps = 37/365 (10%) Query: 20 IKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-FPVIV 78 ++ K ++ + + F + ++V I IL GIC +D H +P+I Sbjct: 3 VQSKGFAIFSKDEHFKPHDFSRHAVGPRDVLIDILYAGICHSDIHSAYSEWKEGIYPMIP 62 Query: 79 GHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 GHE GI++ +G+GV K GD V + F+ C+ C C+ C + T Sbjct: 63 GHEIAGIIKEVGKGVKKFKIGDVVGVGCFVNSCKACKPCKEHQEQFCTKVVFT------- 115 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVK 197 + C + + ++ VVDE+ V +D AP EKV + C T Y +K Sbjct: 116 ----YDCLDSFHDNEPHMGGYSNNIVVDENYVISVDKNAPLEKVAPLLCAGITTYSP-LK 170 Query: 198 TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI-SPK 256 KV G+ V G GG+G + + GA + N+ K + A+++G PK Sbjct: 171 FSKVTKGTKVGVAGFGGLGSMAVKYAVAMGA-EVSVFARNEHKKQDALSMGVKHFYTDPK 229 Query: 257 DSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP--SAKMLT 314 + + + I + D L N G +VG+PP A +L+ Sbjct: 230 QCKEEL------------DFIISTIPTHYDLKDYLKLLTYN-GDLALVGLPPVEVAPVLS 276 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELL 374 + R G + GG+K ++ K ++ I +L K I + L Sbjct: 277 VFDFIHLGNRKVYGSLIGGIKETQEMVDFSI-----KHNIYPEIDLILG-KDIDTAYHNL 330 Query: 375 NSGQS 379 G++ Sbjct: 331 THGKA 335 >1KEV-A nrPDB Length = 351 Score = 233 bits (595), Expect = 8e-62, Method: Composition-based stats. Identities = 88/357 (24%), Positives = 144/357 (40%), Gaps = 41/357 (11%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEG 92 E E + + ++ LA C +D H V +G + + +I+GHEA G V +G Sbjct: 12 LGWIEKERPVAGSYDAIVRPLAVSPCTSDIHTVFEGALGDRKNMILGHEAVGEVVEVGSE 71 Query: 93 VTTVKPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHH 151 V KPGD+VI P P R + + G + Sbjct: 72 VKDFKPGDRVIVPCTTPDWRSLEVQAGFQQH-----------------SNGMLAGWKFSN 114 Query: 152 FMNTSTFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 209 F F EY V+++ ++A + P E +I +TG+ A + ++ GS+ VV Sbjct: 115 F-KDGVFGEYFHVNDADMNLAILPKDMPLENAVMITDMMTTGFHGA-ELADIQMGSSVVV 172 Query: 210 FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEM 269 G+G VGL I G K GA RIIG+ E A GAT+ ++ K+ + +V+ Sbjct: 173 IGIGAVGLMGIAGAKLRGAGRIIGVGSRPICVEAAKFYGATDILNYKNG-HIVDQVMKLT 231 Query: 270 TGNNVGYTFEVIGHLETMIDALASCHMN--------YGTSVVVGVPPSAKMLTYDPMLLF 321 G V G ET+ A++ +G+ + +P Sbjct: 232 NGKGVDRVIMAGGGSETLSQAVSMVKPGGIISNINYHGSGDALLIPRVEWGCG------M 285 Query: 322 TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSG 377 +T KG + G + R ++ + + + + DL +L+THV F I E L+ Sbjct: 286 AHKTIKGGLCPGGRLRAEMLRDMVVY--NRVDLSKLVTHVYHGFDHIEEALLLMKDK 340 >4EJ6-A nrPDB Length = 370 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 82/368 (22%), Positives = 132/368 (35%), Gaps = 39/368 (10%) Query: 25 AVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATG 84 AV E S+ + + P ++ +K+ A GIC TD H++ G S PV +GHE G Sbjct: 26 AVRLESVGNISVRNVGIPEPGPDDLLVKVEACGICGTDRHLLHGEFPSTPPVTLGHEFCG 85 Query: 85 IVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 IV G V + PG ++ C C C+ NLC G Sbjct: 86 IVVEAGSAVRDIAPGARITGDPNISCGRCPQCQAGRVNLCRNLRAIGI------------ 133 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVC---LIGCGFSTGYGAAVKTGKV 201 F EY +V +I P + C V + Sbjct: 134 --------HRDGGFAEYVLVPRKQAFEIPLTLDPVHGAFCEPLACCLH-----GVDLSGI 180 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP 261 K GST + G G +GL + + AGA+ +I K A VGAT + P S Sbjct: 181 KAGSTVAILGGGVIGLLTVQLARLAGATTVILSTRQATKRRLAEEVGATATVDP--SAGD 238 Query: 262 ISEVLSEMTG---NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 + E ++ G V E G ET+ + GT V++GV P + + +P Sbjct: 239 VVEAIAGPVGLVPGGVDVVIECAGVAETVKQSTRLA-KAGGTVVILGVLPQGEKVEIEPF 297 Query: 319 -LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG 377 +LF G R + ++D++I+ + + + + Sbjct: 298 DILFRELRVLGSFINPFVHR----RAADLVATGAIEIDRMISRRISLDEAPDVISNPAAA 353 Query: 378 QSIRTVLT 385 ++ ++ Sbjct: 354 GEVKVLVI 361 >5K1S-A nrPDB Length = 362 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 87/369 (23%), Positives = 140/369 (37%), Gaps = 35/369 (9%) Query: 23 KAAVLWEQK--QPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIVG 79 KA VL +E + + P EV +++ A G+C D +G + + P I+G Sbjct: 19 KAVVLRSFGEAGNLKMETMPMPRPGRGEVLLRVHACGVCYHDVINRRGNLPRTSVPAILG 78 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 HEA G V +G K GD+ L C +C CR+ +LC + L Sbjct: 79 HEAAGEVIEVGPDTPGWKTGDRAATLQRMSCGDCALCRSGRNSLCKTDNRFFGEEL---- 134 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + ++ V + ++ + P + + C T G Sbjct: 135 ---------------PGGYAQFMVAPVGGLGRVPASLPWNEAATVCCTTGTAVHTVRTRG 179 Query: 200 KVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 KV+ G T ++ G GGVGLS + + GA R+I + ++ K + GA E I + Sbjct: 180 KVRAGETVLITGASGGVGLSSVQLARLDGA-RVIAVTSSEAKVQALKEAGADEVIVSR-G 237 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 S+V G V E++G T L S G VVVG + M+ +P Sbjct: 238 LDFASDVRKRTQGAGVDVAVEIVGS-ATFDQTLKSMAPG-GRVVVVG-NLESGMVQLNPG 294 Query: 319 LLF-TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEG-FELLNS 376 L+ G D+ +L + Q +T +P + ++ F L N Sbjct: 295 LVIVKELEILGAYATTQAELDEALRLTATG-----GVRQFVTDAVPLAEAAKAHFRLENR 349 Query: 377 GQSIRTVLT 385 + R VL Sbjct: 350 EVAGRLVLV 358 >2H6E-A nrPDB Length = 344 Score = 228 bits (580), Expect = 5e-60, Method: Composition-based stats. Identities = 94/379 (24%), Positives = 160/379 (42%), Gaps = 48/379 (12%) Query: 19 VIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKG---TMVSKFP 75 ++K KAA+L + +P SIE++ + P+ +EV I+I G+CRTD V KG + P Sbjct: 1 MVKSKAALLKKFSEPLSIEDVNIPEPQGEEVLIRIGGAGVCRTDLRVWKGVEAKQGFRLP 60 Query: 76 VIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVL 135 +I+GHE G + +GE + VK GD V+ C CR N+C I G+ Sbjct: 61 IILGHENAGTIVEVGE-LAKVKKGDNVVVYATWGDLTCRYCREGKFNICKNQIIPGQ--- 116 Query: 136 ADGTTRFTCKGKPVHHFMNTSTFTEYTVVDES-SVAKIDDAAPPEKVCLIGCGFSTGYGA 194 F+EY +V S + K++ +P E + +T GA Sbjct: 117 -----------------TTNGGFSEYMLVKSSRWLVKLNSLSPVE-AAPLADAGTTSMGA 158 Query: 195 AVKTG-----KVKPGSTCVVFGLGGVGLSVIMGCKSAGAS-RIIGIDLNKDKFEKAMAVG 248 + +P +V G+GG+ + I K+ + I+GI +K + A+ +G Sbjct: 159 IRQALPFISKFAEP--VVIVNGIGGLAVYTIQILKALMKNITIVGISRSKKHRDFALELG 216 Query: 249 ATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP 308 A KD+ I+ G +++G ET + L G ++VG+ Sbjct: 217 ADYVSEMKDAESLIN---KLTDGLGASIAIDLVGTEETTYN-LGKLLAQEGAIILVGM-- 270 Query: 309 SAKMLTYDPMLLFT-GRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKI 367 K ++ + + G +G L +DV +L K + + +P I Sbjct: 271 EGKRVSLEAFDTAVWNKKLLGSNYGSLNDLEDVVRLSESGKIKPYIIK------VPLDDI 324 Query: 368 SEGFELLNSGQS-IRTVLT 385 ++ F L+ G+ R V+T Sbjct: 325 NKAFTNLDEGRVDGRQVIT 343 >5Z0C-A nrPDB Length = 374 Score = 226 bits (577), Expect = 9e-60, Method: Composition-based stats. Identities = 93/369 (25%), Positives = 145/369 (39%), Gaps = 37/369 (10%) Query: 14 GTAGKVIKCKAAVLWEQKQP---FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM 70 GT +K AV W + P S +V K+L GIC +D H IK Sbjct: 6 GTEEHTVK---AVGWAARDPSGHLSPFTFSRRATGELDVTFKVLYCGICHSDLHYIKNEW 62 Query: 71 VSK-FPVIVGHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSD 128 + +P + GHE G V +G V K GDKV + + C C C N N C Sbjct: 63 SNTIYPALPGHEIVGEVTEVGSKVNKFKVGDKVGVGCIVGSCHSCPNCNNHLENYCPNRI 122 Query: 129 ITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGF 188 +T DGT +N +++ VV E +I DA P + + C Sbjct: 123 LTFGSRYYDGT-------------LNHGGYSDLMVVQEHFAVRIPDALPLDSAAPLLCAG 169 Query: 189 STGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA-V 247 T Y G KPG V GLGG+G + K+ G ++ + + K E A++ + Sbjct: 170 ITVYSPLRYYGLDKPGLHVGVVGLGGLGHMAVKFAKAFGV-KVTVVSTSPAKKEDAISGL 228 Query: 248 GATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVP 307 GA I D+ + + V + + + + L S ++G V+VG P Sbjct: 229 GAHSFILSTDAEQMQAAV------GTMDGIIDTVSASHPL-PPLISLLKSHGKLVMVGDP 281 Query: 308 PSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKI 367 P L P LL + G GG+K ++ +F AK+ + V+P + Sbjct: 282 PKPLELPVFP-LLLGRKMVAGSAIGGMKETQEM----IDFAAKEGV--RADVEVIPMDYV 334 Query: 368 SEGFELLNS 376 + + ++ Sbjct: 335 NTAMQRVSK 343 >1YQX-A nrPDB Length = 366 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 80/354 (22%), Positives = 136/354 (38%), Gaps = 33/354 (9%) Query: 27 LWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIVGHEATGI 85 +Q S ++VR K+L G+C +D H IK S +P++ GHE G Sbjct: 22 ARDQSGHLSPFNFSRRATGEEDVRFKVLYCGVCHSDLHSIKNDWGFSMYPLVPGHEIVGE 81 Query: 86 VESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 V +G V V GDKV + + C C +C N N C + +T + DGT + Sbjct: 82 VTEVGSKVKKVNVGDKVGVGCLVGACHSCESCANDLENYCPKMILTYASIYHDGTITY-- 139 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPG 204 ++ + V +E + + D P + + C T Y G +PG Sbjct: 140 -----------GGYSNHMVANERYIIRFPDNMPLDGGAPLLCAGITVYSPLKYFGLDEPG 188 Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKA-MAVGATECISPKDSTKPIS 263 + GLGG+G + K+ G S++ I + K E+A GA + +D + + Sbjct: 189 KHIGIVGLGGLGHVAVKFAKAFG-SKVTVISTSPSKKEEALKNFGADSFLVSRDQEQMQA 247 Query: 264 EVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTG 323 + + + + ++ ++G ++VG P K L L G Sbjct: 248 AA------GTLDGIIDTVSAVHPLLPLFG-LLKSHGKLILVGAP--EKPLELPAFSLIAG 298 Query: 324 RTW-KGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 R G GG+K ++ +F AK + V+ ++ E L Sbjct: 299 RKIVAGSGIGGMKETQEM----IDFAAKHNITADI--EVISTDYLNTAMERLAK 346 >3M6I-A nrPDB Length = 363 Score = 225 bits (573), Expect = 3e-59, Method: Composition-based stats. Identities = 73/362 (20%), Positives = 140/362 (38%), Gaps = 36/362 (9%) Query: 27 LWEQKQPFSIEEIEVAPP-KTKEVRIKILATGICRTDDHVIK----GTMVSKFPVIVGHE 81 LW + S+E ++ K EV + + +TGIC +D H K G M+ + ++GHE Sbjct: 20 LWISEASPSLESVQKGEELKEGEVTVAVRSTGICGSDVHFWKHGCIGPMIVECDHVLGHE 79 Query: 82 ATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTR 141 + G V ++ V ++K GD+V C C C N C R D + R Sbjct: 80 SAGEVIAVHPSVKSIKVGDRVAIEPQVICNACEPCLTGRYNGCERVDFLSTPPVPGLLRR 139 Query: 142 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 + H + ++ +++ SVA A ++ V Sbjct: 140 YVNHPAVWCHKIGNMSYENGAMLEPLSVAL----------------------AGLQRAGV 177 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG---ATECISPKDS 258 + G ++ G G +GL ++ K+AGA ++ D+++ + + A + T + + Sbjct: 178 RLGDPVLICGAGPIGLITMLCAKAAGACPLVITDIDEGRLKFAKEICPEVVTHKVERLSA 237 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 + +++ G E G +E+ I A G V+GV + + P Sbjct: 238 EESAKKIVESFGGIEPAVALECTG-VESSIAAAIWAVKFGGKVFVIGVGKNEIQI---PF 293 Query: 319 LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 378 + + R + + P+ + DL +L+TH P + + FE + + Sbjct: 294 MRASVREVDLQFQ--YRYCNTWPRAIRLVENGLVDLTRLVTHRFPLEDALKAFETASDPK 351 Query: 379 SI 380 + Sbjct: 352 TG 353 >4GKV-A nrPDB Length = 336 Score = 223 bits (569), Expect = 7e-59, Method: Composition-based stats. Identities = 92/366 (25%), Positives = 146/366 (39%), Gaps = 35/366 (9%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEA 82 KAAV+ + + + K E +K+ G+C TD HV G K VI+GHE Sbjct: 2 KAAVV-TKDHHVDVTYKTLRSLKHGEALLKMECCGVCHTDLHVKNGDFGDKTGVILGHEG 60 Query: 83 TGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTR 141 G+V +G GVT++KPGD+ + F C C C + + LC G V Sbjct: 61 IGVVAEVGPGVTSLKPGDRASVAWFYEGCGHCEYCNSGNETLCRSVKNAGYSV------- 113 Query: 142 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 E +V K+ D I C T Y AVK K+ Sbjct: 114 -------------DGGMAEECIVVADYAVKVPDGLDSAAASSITCAGVTTY-KAVKLSKI 159 Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP 261 +PG ++GLGG+G + K+ +++I ID+N ++ + A +GA I+ T+ Sbjct: 160 RPGQWIAIYGLGGLGNLALQYAKNVFNAKVIAIDVNDEQLKLATEMGADLAINS--HTED 217 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLF 321 ++++ E TG V + ++ G V VG+PP + L P L+ Sbjct: 218 AAKIVQEKTGGAHAAV--VTAVAKAAFNSAVDAVRAGGRVVAVGLPPESMSLDI-PRLVL 274 Query: 322 TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ-SI 380 G G + G + + + E K + P I+ F + G+ Sbjct: 275 DGIEVVGSLVGTRQDLTEAFQFAAE---GKVVPK---VALRPLADINTIFTEMEEGKIRG 328 Query: 381 RTVLTF 386 R V+ F Sbjct: 329 RMVIDF 334 >2OUI-A nrPDB Length = 360 Score = 223 bits (568), Expect = 1e-58, Method: Composition-based stats. Identities = 84/355 (23%), Positives = 140/355 (39%), Gaps = 41/355 (11%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDH-VIKGTMVSKFPVIVGHEATGIVESIGEGVTTV 96 E ++ + ++ LA C +D H V G + + +I+GHEA G + +G V + Sbjct: 16 EKKIPECGPLDALVRPLALAPCTSDTHTVWAGAIGDRHDMILGHEAVGQIVKVGSLVKRL 75 Query: 97 KPGDKVI-PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 K GDKVI P P E + R + G+L G +F+ Sbjct: 76 KVGDKVIVPAITPDWGEEESQRG--------YPMHSGGML--GGWKFSN--------FKD 117 Query: 156 STFTEYTVVDES--SVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG 213 F+E V+E+ ++A + PE ++ +TG+ A + +K G T V G+G Sbjct: 118 GVFSEVFHVNEADANLALLPRDIKPEDAVMLSDMVTTGFHGA-ELANIKLGDTVCVIGIG 176 Query: 214 GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNN 273 VGL + G GA RI + K + A+ GAT+ I+ K+ + ++L G Sbjct: 177 PVGLMSVAGANHLGAGRIFAVGSRKHCCDIALEYGATDIINYKNG-DIVEQILKATDGKG 235 Query: 274 VGYTFEVIGHLETMIDALASCHMN--------YGTSVVVGVPPSAKMLTYDPMLLFTGRT 325 V G + T A+ G + +P S + + G T Sbjct: 236 VDKVVIAGGDVHTFAQAVKMIKPGSDIGNVNYLGEGDNIPIPRSEWGVGMGHKHIHGGLT 295 Query: 326 WKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-FKKISEGFELLNSGQS 379 G R + KL + K D +LITH +K+ + L+ + + Sbjct: 296 PGG--------RVRMEKLASLISTGKLDTSKLITHRFEGLEKVEDALMLMKNKPA 342 >6DKH-A nrPDB Length = 346 Score = 222 bits (566), Expect = 2e-58, Method: Composition-based stats. Identities = 70/342 (20%), Positives = 125/342 (36%), Gaps = 34/342 (9%) Query: 50 RIKILATGICRTDDHVIK----GTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPL 105 ++I GIC +D H + G + K P+++GHE G V I + + G V Sbjct: 34 LVQITRGGICGSDLHYYQEGKVGNFMIKAPMVLGHEVIGKV--IHSDSSELHEGQTVAIN 91 Query: 106 FLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVD 165 C C C + N C G + + FT Y +V+ Sbjct: 92 PSKPCGHCKYCIEHNENQCTDMRFFGSAM---------------YFPHVDGGFTRYKMVE 136 Query: 166 ESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKS 225 S A EKV + AA + G+++ G + G+G +G ++ K+ Sbjct: 137 TSQCVPYPAKAD-EKVMAFAEPLAVAIHAAHQAGELQ-GKRVFISGVGPIGCLIVSAVKT 194 Query: 226 AGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLE 285 GA+ I+ D++ +GA ++P++ + +E +FEV GH Sbjct: 195 LGAAEIVCADVSPRSLSLGKEMGADVLVNPQN--DDMDHWKAEK--GYFDVSFEVSGHPS 250 Query: 286 TMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVT 345 ++ L G V VG+ + PM+ G+ + G + + V+ Sbjct: 251 SVNTCLE-VTRARGVMVQVGM---GGAMAEFPMMTLIGKEI--SLRGSFRFTSEFNTAVS 304 Query: 346 EFLAKKFDLDQLITHVLPFKKISEGFELL-NSGQSIRTVLTF 386 + L++ PF + E + Q+ + L F Sbjct: 305 WLANGVINPLPLLSAEYPFTDLEEALRFAGDKTQAAKVQLVF 346 >3IP1-A nrPDB Length = 404 Score = 221 bits (562), Expect = 6e-58, Method: Composition-based stats. Identities = 79/383 (20%), Positives = 138/383 (36%), Gaps = 46/383 (12%) Query: 27 LWEQKQPFSIEEIEVAPP-KTKEVRIKILATGICRTDDHVIKGTM--------VSKFPVI 77 +W + +EE+ K E+ IK+ A GIC +D H+ + ++ FPV Sbjct: 36 VWRYPE-VRVEEVPEPRIEKPTEIIIKVKACGICGSDVHMAQTDEEGYILYPGLTGFPVT 94 Query: 78 VGHEATGIVESIGEGV------TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG 131 +GHE +G+V G + G+ V + C C C N C + G Sbjct: 95 LGHEFSGVVVEAGPEAINRRTNKRFEIGEPVCAEEMLWCGHCRPCAEGFPNHCENLNELG 154 Query: 132 RGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDD------AAPPEKVCLIG 185 F F EY VD + + + Sbjct: 155 --------------------FNVDGAFAEYVKVDAKYAWSLRELEGVYEGDRLFLAGSLV 194 Query: 186 CGFSTGYGAA-VKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKA 244 S Y A V+ G ++PG V+ G G +GL+ + K AGAS++I + ++ + A Sbjct: 195 EPTSVAYNAVIVRGGGIRPGDNVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLA 254 Query: 245 MAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASC-HMNYGTSVV 303 +GA I P + VL G E G + + + G + Sbjct: 255 KELGADHVIDPTK-ENFVEAVLDYTNGLGAKLFLEATGVPQLVWPQIEEVIWRARGINAT 313 Query: 304 VGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP 363 V + A +F R + G P++++ +A D+ ++I+ + Sbjct: 314 VAIVARADAKIPLTGEVFQVRRAQIVGSQGHSGHGTFPRVIS-LMASGMDMTKIISKTVS 372 Query: 364 FKKISEGFELLNSGQSIRTVLTF 386 ++I E + L + +S+ V Sbjct: 373 MEEIPEYIKRLQTDKSLVKVTML 395 >4OAQ-A nrPDB Length = 367 Score = 220 bits (560), Expect = 9e-58, Method: Composition-based stats. Identities = 75/371 (20%), Positives = 144/371 (38%), Gaps = 43/371 (11%) Query: 28 WEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS--KFPVIVGHEATGI 85 W + + S E ++ +V +K G+C +D H + + ++VGHE G Sbjct: 20 WNRPKLASYERKQIN---PHDVVLKNEVCGLCYSDIHTLSAGWQPLQRDNLVVGHEIIGE 76 Query: 86 VESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 V ++G+ VT K GD+V I CR C C + + C + G + Sbjct: 77 VIAVGDEVTEFKVGDRVGIGAASSSCRSCQRCDSDNEQYCKQ-----------GAATYNS 125 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP- 203 K ++++ ++ +++ DE V I + P + C T + ++ + Sbjct: 126 KDVRSNNYVTQGGYSSHSIADEKFVFAIPEDLPSSYGAPLMCAGITVFSPLIRNLGLDAR 185 Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G + G+GG+G + + GA+ + + K E+AM +GA + ++ + Sbjct: 186 GKNVGIIGIGGLGHLALQFANAMGAN-VTAFSRSSSKKEQAMKLGAHDFVATGE------ 238 Query: 264 EVLSEMTGNNVGYTFEVIGHLETMIDALA-----SCHMNYGTSVVVGVPPSAKMLTYDPM 318 + N F+ I + + ID L S V VG+PPS P Sbjct: 239 ---DKTWYKNYDDHFDFILNCASGIDGLNLSEYLSTLKVDKKFVSVGLPPSEDKFEVSPF 295 Query: 319 LLF-TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKIS--EGFELLN 375 G ++ + G ++ L A K ++ +I V P + + + + + Sbjct: 296 TFLQQGASFGSSLLGSKTEVKEMLNL-----AAKHNVRPMIEEV-PISEENCAKALDRCH 349 Query: 376 SGQSIRTVLTF 386 +G +R F Sbjct: 350 AGD-VRYRFVF 359 >6FG0-A nrPDB Length = 352 Score = 217 bits (553), Expect = 6e-57, Method: Composition-based stats. Identities = 88/360 (24%), Positives = 132/360 (36%), Gaps = 31/360 (8%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK---GTMVSKFPVIVG 79 KA E + +I P E+ +K+ A G+C +D V+ P+ +G Sbjct: 2 KAVQYTEIGSEPVVVDIPTPTPGPGEILLKVTAAGLCHSDITVMDMPAAQYAGGLPLTLG 61 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 HE G V +GEGVT GD V C C+AC N C Sbjct: 62 HEGVGTVAELGEGVTGFGVGDAVAVYGPWGCGACHACARGRENYC--------------- 106 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVD-ESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVK- 197 TR G + + + EY +VD + I D P + T Y A + Sbjct: 107 TRAADLGITPPGYGSPGSMAEYMIVDSARHLVPIGDLDPV-AAAPLTDAGLTPYHAISRV 165 Query: 198 TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 + PGST VV G+GG+G I ++ A+R+I +DL+ D+ A VGA + K Sbjct: 166 LPLLGPGSTAVVIGVGGLGHVGIQILRAVSAARVIAVDLDDDRLALAREVGADAAV--KS 223 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP 317 + G F+ +G T ID G VVG+ A Sbjct: 224 GAGAADAIRELTGGQGATAVFDFVGAQST-IDTAQQVVAVDGHISVVGIHAGAHAKVGFW 282 Query: 318 MLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSG 377 M+ F V +R ++ ++V A + D + T + + L G Sbjct: 283 MIPFGASV----VTPYWGTRSELMEVVALARAGRLD---IHTETFTLDEGPAAYRRLREG 335 >1Q1N-A nrPDB Length = 360 Score = 211 bits (537), Expect = 4e-55, Method: Composition-based stats. Identities = 87/369 (23%), Positives = 142/369 (38%), Gaps = 45/369 (12%) Query: 28 WEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS-KFPVIVGHEATGIV 86 W+ + + ++ IKI A G+C +D H G + K P++VGHE G V Sbjct: 18 WKNPKKTKYDPKPF---YDHDIDIKIEACGVCGSDIHCAAGHWGNMKMPLVVGHEIVGKV 74 Query: 87 ESIGEGV-TTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTC 144 +G + +K G +V + + C EC+ C+N + C + T DG Sbjct: 75 VKLGPKSNSGLKVGQRVGVGAQVFSCLECDRCKNDNEPYCTKFVTTYSQPYEDG------ 128 Query: 145 KGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPG 204 +++ + Y V E V I + P + CG T Y V+ G PG Sbjct: 129 -------YVSQGGYANYVRVHEHFVVPIPENIPSHLAAPLLCGGLTVYSPLVRNGC-GPG 180 Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 + GLGG+G + K+ GA + I + K E AM +GA I+ + Sbjct: 181 KKVGIVGLGGIGSMGTLISKAMGAETYV-ISRSSRKREDAMKMGADHYIATLEEGD---- 235 Query: 265 VLSEMTGNNVGYTFEVIGHLETMIDAL-----ASCHMNYGTSVVVGVPPSAKMLTYDPML 319 G TF++I + + + G V + +P +ML+ P Sbjct: 236 -----WGEKYFDTFDLIVVCASSLTDIDFNIMPKAMKVGGRIVSISIPEQHEMLSLKPYG 290 Query: 320 LFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKK--ISEGFELLNSG 377 L + G +K + + KLV+E K + LP + + E FE + G Sbjct: 291 L-KAVSISYSALGSIKELNQLLKLVSEKDIK------IWVETLPVGEAGVHEAFERMEKG 343 Query: 378 QSIRTVLTF 386 +R T Sbjct: 344 D-VRYRFTL 351 >4UEJ-A nrPDB Length = 346 Score = 209 bits (533), Expect = 1e-54, Method: Composition-based stats. Identities = 78/368 (21%), Positives = 138/368 (37%), Gaps = 32/368 (8%) Query: 25 AVLWEQKQPFSIEEIEVAPPKT-KEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEAT 83 +V+ + + E + K EVR+KI ++G+C +D I +P+ +GHE + Sbjct: 3 SVVNDTDGIVRVAESVIPEIKHQDEVRVKIASSGLCGSDLPRIFKNGAHYYPITLGHEFS 62 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFT 143 G ++++G GV + PGD V + L C C C + C + D G Sbjct: 63 GYIDAVGSGVDDLHPGDAVACVPLLPCFTCPECLKGFYSQCAKYDFIGS----------- 111 Query: 144 CKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP 203 F EY VV +V + P E I + G A + Sbjct: 112 ---------RRDGGFAEYIVVKRKNVFALPTDMPIEDGAFIE-PITVGLH-AFHLAQGCE 160 Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP-I 262 ++ G G +GL I + GA + ID++ +K A + GA + + + + P + Sbjct: 161 NKNVIIIGAGTIGLLAIQCAVALGAKSVTAIDISSEKLALAKSFGAMQTFNSSEMSAPQM 220 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM--LL 320 VL E+ N + E G +T+ A+ + +VG LT +L Sbjct: 221 QSVLRELRFNQL--ILETAGVPQTVELAVEIA-GPHAQLALVGTLHQDLHLTSATFGKIL 277 Query: 321 FTGRTWKGC--VFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF-ELLNSG 377 T G + + +K L+ LI H F+ ++ ++ + Sbjct: 278 RKELTVIGSWMNYSSPWPGQEWETASRLLTERKLSLEPLIAHRGSFESFAQAVRDIARNA 337 Query: 378 QSIRTVLT 385 + +L Sbjct: 338 MPGKVLLI 345 >5VKT-A nrPDB Length = 362 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 85/361 (23%), Positives = 138/361 (38%), Gaps = 32/361 (8%) Query: 22 CKAAVLWEQK---QPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVI 77 CK A W + S +V IK+L GIC TD HVIK + +PV+ Sbjct: 7 CKTAHGWAARDASGHLSPYSFSARIQGDADVTIKVLFCGICHTDLHVIKNEWGNAMYPVV 66 Query: 78 VGHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLA 136 GHE G+V +G GVT K GD V + F+ CR C +C N C +T GV Sbjct: 67 PGHEVVGVVTDVGHGVTKFKAGDTVGVGYFVDSCRTCESCSTGHENYCPDLVLTSNGVDH 126 Query: 137 DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAV 196 H F++ VV + V ++ ++ P + + C T Y Sbjct: 127 -----------HHHGATTKGGFSDVLVVSQDFVVRVPESLPLDGAAPLLCAGVTVYSPMA 175 Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAM-AVGATECISP 255 + +PG V GLGG+G + K+ G + I + K ++A+ +GA + Sbjct: 176 QYALNEPGKHLGVVGLGGLGHMAVKFAKAFGM-TVTVISSSPGKRDEALGRLGADAFLVS 234 Query: 256 KDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTY 315 D+ + + + + + + ++ LA G VVVG P + L Sbjct: 235 HDAAQMKAAAAT------LDGIIDTVSAGHQIVPLLA-LLKPMGQMVVVGAPSTPLELPA 287 Query: 316 DPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLN 375 ++ G+ G G + + A + + I V+ ++ E L Sbjct: 288 YAIIT-GGKRVAGNGVGSVADCQAMLDF-----AGEHGVTADI-EVVQMDYVNTAIERLE 340 Query: 376 S 376 Sbjct: 341 K 341 >3UOG-A nrPDB Length = 363 Score = 203 bits (517), Expect = 9e-53, Method: Composition-based stats. Identities = 73/355 (20%), Positives = 132/355 (37%), Gaps = 34/355 (9%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS--KFPVIVGHEATGIVESIGE 91 + E V ++ ++ LA + D V++ M FP + + +G+VE++G+ Sbjct: 41 LKLAERPVPEAGEHDIIVRTLAVSLNYRDKLVLETGMGLDLAFPFVPASDMSGVVEAVGK 100 Query: 92 GVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHH 151 VT +PGD+VI F P + R G + G Sbjct: 101 SVTRFRPGDRVISTFAPGWL--DGLRPGTGRTPAYETLGGA------------------- 139 Query: 152 FMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFG 211 + +EY V+ E + + + C T + A V+ G ++ G VV G Sbjct: 140 --HPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWFALVEKGHLRAGDRVVVQG 197 Query: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 GGV L + K+ GA +I +++K ++A A+GA I+ + + V + Sbjct: 198 TGGVALFGLQIAKATGA-EVIVTSSSREKLDRAFALGADHGIN-RLEEDWVERVYALTGD 255 Query: 272 NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVF 331 + E+ G G V+GV ++ LL +G Sbjct: 256 RGADHILEIAGGAGLGQSL--KAVAPDGRISVIGVLEGFEVSGPVGPLLLKSPVVQGISV 313 Query: 332 GGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF 386 G ++ +D+ V + L +I F ++ E L+ G + V+ F Sbjct: 314 GHRRALEDLVGAVD-----RLGLKPVIDMRYKFTEVPEALAHLDRGPFGKVVIEF 363 >6C49-A nrPDB Length = 350 Score = 194 bits (492), Expect = 6e-50, Method: Composition-based stats. Identities = 73/369 (19%), Positives = 135/369 (36%), Gaps = 42/369 (11%) Query: 21 KCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-FPVIVG 79 +A + + + + + +V +K+ G+C +D V+ S +PV+ G Sbjct: 13 TIQAYAAMQAGEKLVPYKFDAGELQPHQVEVKVEYCGLCHSDISVLNNEWHSTVYPVVAG 72 Query: 80 HEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 HE G + ++G ++ G +V I C+ C+ C LC +I Sbjct: 73 HEIIGRIVALGSEAKGLQIGQRVGIGWTAESCQACDECIGGQQVLCTGENI--------- 123 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 + F + + + PE + CG T + +K Sbjct: 124 ----------ATIVGHAGGFADKVRAGWQWAIPLPEDLDPESAGPLLCGGITVFDPLLKH 173 Query: 199 GKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 K++ V G+GG+G I K+ G I N DK E+ A+GA ++ +D+ Sbjct: 174 -KIQATHHVGVIGIGGLGHIAIKLLKAWG-CEITAFSSNPDKTEELKAMGADHVVNSRDT 231 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 ++ ++ A S G+ +G+ T +P+ Sbjct: 232 EAVKAQ-------KGKFDLLLSTVNVTLNWRAFISTLAPNGSLHFLGL-------TLEPV 277 Query: 319 LLFTGRTWKG--CVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 + G G V G + + +F A+K Q+ + P +++E E L+S Sbjct: 278 PVSVGSLIDGAKSVTGSPTGSPAALRQLLKFAARKKIAPQI--ELFPMSQLNEAIERLHS 335 Query: 377 GQS-IRTVL 384 GQ+ R VL Sbjct: 336 GQARYRIVL 344 >5FI5-A nrPDB Length = 357 Score = 191 bits (484), Expect = 6e-49, Method: Composition-based stats. Identities = 72/359 (20%), Positives = 125/359 (34%), Gaps = 37/359 (10%) Query: 20 IKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIV 78 +K + FS +V++K+L G C+ D + K + +P ++ Sbjct: 16 VKAFGLAAKDSSGLFSPFNFSRRATGEHDVQLKVLYCGTCQYDREMSKNKFGFTSYPYVL 75 Query: 79 GHEATGIVESIGEGVTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 GHE G V +G V K GDKV + + C +C C N N C + Sbjct: 76 GHEIVGEVTEVGSKVQKFKVGDKVGVASIIETCGKCEMCTNEVENYCPEAGSIDS----- 130 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVK 197 N + V++E+ V + + P + + C T Y + Sbjct: 131 ----------------NYGACSNIAVINENFVIRWPENLPLDSGVPLLCAGITAYSPMKR 174 Query: 198 TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 G KPG + GLGG+G + K+ GA + K K E GA + + Sbjct: 175 YGLDKPGKRIGIAGLGGLGHVALRFAKAFGAKVTVISSSLKKKREAFEKFGADSFLVSSN 234 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP 317 + + + I ++ LA G +++G P + P Sbjct: 235 PEEMQGAA------GTLDGIIDTIPGNHSLEPLLA-LLKPLGKLIILGAPEMPFEVP-AP 286 Query: 318 MLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 LL G+ G +K ++ EF A+ + V+ ++ E L++ Sbjct: 287 SLLMGGKVMAASTAGSMKEIQEM----IEFAAEHNIVAD--VEVISIDYVNTAMERLDN 339 >5H83-A nrPDB Length = 360 Score = 189 bits (480), Expect = 2e-48, Method: Composition-based stats. Identities = 76/345 (22%), Positives = 122/345 (35%), Gaps = 33/345 (9%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIVGHEATGIVESIGEG 92 FS +V+ K+L G C D + +K+P ++GHE G+V IG Sbjct: 27 FSPFNFSRRATGENDVQFKVLYCGTCNYDLEMSTNKFGMTKYPFVIGHEIVGVVTEIGSK 86 Query: 93 VTTVKPGDKV-IPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHH 151 V K GDKV + F+ C +C C N N C + + T H Sbjct: 87 VQKFKVGDKVGVGGFVGACEKCEMCVNGVENNCSKVESTDG-----------------HF 129 Query: 152 FMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFG 211 N VV+E + P + C T Y + G KPG + G Sbjct: 130 GNNFGGCCNIMVVNEKYAVVWPENLPLHSGVPLLCAGITTYSPLRRYGLDKPGLNIGIAG 189 Query: 212 LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 LGG+G I K+ GA + K K E G + + + Sbjct: 190 LGGLGHLAIRFAKAFGAKVTLISSSVKKKREALEKFGVDSFLLNSNPEEMQGA------Y 243 Query: 272 NNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVF 331 + + + +++ LA G +++GVP + P LL G+ G Sbjct: 244 GTLDGIIDTMPVAHSIVPFLA-LLKPLGKLIILGVPEEPFEVP-APALLMGGKLIAGSAA 301 Query: 332 GGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 G +K ++ +F AK + V+P ++ E + + Sbjct: 302 GSMKETQEM----IDFAAKHNIVAD--VEVIPIDYLNTAMERIKN 340 >4JLW-A nrPDB Length = 399 Score = 184 bits (466), Expect = 7e-47, Method: Composition-based stats. Identities = 84/394 (21%), Positives = 150/394 (38%), Gaps = 53/394 (13%) Query: 32 QPFSIEEIEVAPPKTKE---------VRIKILATGICRTDDHVIKGTMVSKFPVIVGHEA 82 P +E + PK ++ V +++++T IC +D H+++G + +++GHE Sbjct: 11 GPGKVEVQNIPYPKMQDPQGRQIDHGVILRVVSTNICGSDQHMVRGRTTAPEGLVLGHEI 70 Query: 83 TGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRF 142 TG V IG GV T+K GD V F C C C+ +C +T A G + Sbjct: 71 TGEVVEIGRGVETMKIGDLVSVPFNVACGHCRTCKEQHTGVC----LTVNPARAGGAYGY 126 Query: 143 TCKGKPVHHFMNTSTFTEYTVVD--ESSVAKID-DAAPPEKVCLIGC---GFSTGYGAAV 196 G EY +V + ++ K+ A EK+ + C TGY AV Sbjct: 127 VDMG------GWVGGQAEYVLVPYADFNLLKLPNREAAMEKIRDLTCLSDILPTGYHGAV 180 Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK 256 T V PGST + G G VGL+ + GA+ +I D+N + A G K Sbjct: 181 -TAGVGPGSTVYIAGAGPVGLAAAASARLLGAAVVIVGDVNPTRLAHAKKQGFEIADLSK 239 Query: 257 DSTKPISEVLSEMTGN-NVGYTFEVIG--------------HLETMIDALASCHMNYGTS 301 D+ P+ E ++ + G V + +G T++++L G Sbjct: 240 DT--PLHEQIAALLGEPEVDCAVDAVGFEARGHGHSGSQQEAPATVLNSLMGITRVAGKI 297 Query: 302 VVVGVPPSAKMLTYDPMLLFTGRTWK--------GCVFGGLKSRDDVPK-LVTEFLAKKF 352 + G+ + D + + G + L+ + + Sbjct: 298 GIPGLYVTEDPGAVDAAAKHGALSIRFGLGWAKSHSFHTGQTPVMKYNRQLMQAIMWDRI 357 Query: 353 DLDQLI-THVLPFKKISEGFELLNSGQSIRTVLT 385 + ++ V+ +G+ ++G + V+ Sbjct: 358 KIADIVGVEVITLDDAPKGYGEFDAGVPKKFVID 391 >1YB5-A nrPDB Length = 351 Score = 180 bits (457), Expect = 8e-46, Method: Composition-based stats. Identities = 73/384 (19%), Positives = 146/384 (38%), Gaps = 65/384 (16%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIE---EIEVAPPKTKEVRIKILATGICRTDDHVIKGT 69 M T K+++ A ++E P ++ +I V PK +V IK+ A G+ + ++ GT Sbjct: 23 MATGQKLMR--AVRVFEFGGPEVLKLRSDIAVPIPKDHQVLIKVHACGVNPVETYIRSGT 80 Query: 70 MVSK--FPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRS 127 K P G + G++E++G+ + K GD+V Sbjct: 81 YSRKPLLPYTPGSDVAGVIEAVGDNASAFKKGDRVFTSSTIS------------------ 122 Query: 128 DITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCG 187 + EY + + +V K+ + ++ IG Sbjct: 123 ----------------------------GGYAEYALAADHTVYKLPEKLDFKQGAAIGIP 154 Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 + T Y A + + VK G + +V G GGVGL+ ++ G +I+G ++ + + Sbjct: 155 YFTAYRALIHSACVKAGESVLVHGASGGVGLAACQIARAYGL-KILGTAGTEEGQKIVLQ 213 Query: 247 VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGV 306 GA E + ++ I ++ + + E++ ++ D S + G +VVG Sbjct: 214 NGAHEVFNHREVNY-IDKIKKYVGEKGIDIIIEMLANVNLSKDL--SLLSHGGRVIVVG- 269 Query: 307 PPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFD--LDQLITHVLPF 364 S + +P + V ++++ + A L +I P Sbjct: 270 --SRGTIEINPRDTMAKESSIIGVTLFSSTKEEFQQYAAALQAGMEIGWLKPVIGSQYPL 327 Query: 365 KKISEGFELL--NSGQSIRTVLTF 386 +K++E E + SG + + +L Sbjct: 328 EKVAEAHENIIHGSGATGKMILLL 351 >3WLE-A nrPDB Length = 341 Score = 174 bits (442), Expect = 4e-44, Method: Composition-based stats. Identities = 77/361 (21%), Positives = 139/361 (38%), Gaps = 40/361 (11%) Query: 27 LWEQKQPFSIE-EIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGI 85 ++ ++ + ++ V PK ++ +K+ A G+C +D HVI + ++GHE G Sbjct: 16 VFNKQSGLKLRNDLPVHKPKAGQLLLKVDAVGLCHSDLHVIYEGLDCGDNYVMGHEIAGT 75 Query: 86 VESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCK 145 V ++G+ V K GD+V + C C CR N+C + G+ DG Sbjct: 76 VAAVGDDVINYKVGDRVACVGPNGCGGCKYCRGAIDNVCKNAFGDWFGLGYDG------- 128 Query: 146 GKPVHHFMNTSTFTEYTVV-DESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPG 204 + +Y +V ++++I D + T Y A+K +V P Sbjct: 129 -----------GYQQYLLVTRPRNLSRIPDNVSADVAAASTDAVLTPYH-AIKMAQVSPT 176 Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 S ++ G GG+G + I K+ GA ++ +D K+ ++A +GA + Sbjct: 177 SNILLIGAGGLGGNAIQVAKAFGA-KVTVLDKKKEARDQAKKLGADAVYETLPES----- 230 Query: 265 VLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGR 324 ++ + F+ + ++ D G + VG+ L Sbjct: 231 ----ISPGSFSACFDFV-SVQATFDVCQKYVEPKGVIMPVGLGAPNLSFNLG-DLALREI 284 Query: 325 TWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQS-IRTV 383 G +G DDV KLV+E K + K++ E E L + R V Sbjct: 285 RILGSFWGTTNDLDDVLKLVSEGKVKP------VVRSAKLKELPEYIEKLRNNAYEGRVV 338 Query: 384 L 384 Sbjct: 339 F 339 >1KOL-A nrPDB Length = 398 Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats. Identities = 82/386 (21%), Positives = 149/386 (38%), Gaps = 48/386 (12%) Query: 35 SIEEIEVAPPKT----KEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIG 90 I+ ++ P+ V +K+++T IC +D H+++G ++ +++GHE TG V G Sbjct: 18 KIDYPKMQDPRGKKIEHGVILKVVSTNICGSDQHMVRGRTTAQVGLVLGHEITGEVIEKG 77 Query: 91 EGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVH 150 V ++ GD V F C C +C+ +C +T A G + G Sbjct: 78 RDVENLQIGDLVSVPFNVACGRCRSCKEMHTGVC----LTVNPARAGGAYGYVDMGD--- 130 Query: 151 HFMNTSTFTEYTVVD--ESSVAKIDD-AAPPEKVCLIGC---GFSTGYGAAVKTGKVKPG 204 T EY +V + ++ K+ D EK+ + C TGY AV T V PG Sbjct: 131 ---WTGGQAEYVLVPYADFNLLKLPDRDKAMEKIRDLTCLSDILPTGYHGAV-TAGVGPG 186 Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 ST V G G VGL+ + GA+ +I DLN + A A G I+ P+ E Sbjct: 187 STVYVAGAGPVGLAAAASARLLGAAVVIVGDLNPARLAHAKAQGFE--IADLSLDTPLHE 244 Query: 265 VLSEMTGN-NVGYTFEVIG--------------HLETMIDALASCHMNYGTSVVVGVPPS 309 ++ + G V + +G T++++L G + G+ + Sbjct: 245 QIAALLGEPEVDCAVDAVGFEARGHGHEGAKHEAPATVLNSLMQVTRVAGKIGIPGLYVT 304 Query: 310 AKMLTYDPMLLFTGRTWK--------GCVFGGLKSRDDVPK-LVTEFLAKKFDLDQLI-T 359 D + + G + L+ + + ++ +++ Sbjct: 305 EDPGAVDAAAKIGSLSIRFGLGWAKSHSFHTGQTPVMKYNRALMQAIMWDRINIAEVVGV 364 Query: 360 HVLPFKKISEGFELLNSGQSIRTVLT 385 V+ G+ ++G + V+ Sbjct: 365 QVISLDDAPRGYGEFDAGVPKKFVID 390 >2DPH-A nrPDB Length = 398 Score = 172 bits (435), Expect = 3e-43, Method: Composition-based stats. Identities = 81/405 (20%), Positives = 150/405 (37%), Gaps = 60/405 (14%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPK------TKEVRIKILATGICRTDDHVIKGTMVSKFPV 76 K+ V + +E + + V +K+++T IC +D H+ +G + Sbjct: 4 KSVVYHGTRD-LRVETVPYPKLEHNNRKLEHAVILKVVSTNICGSDQHIYRGRFIVPKGH 62 Query: 77 IVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLA 136 ++GHE TG V G V + GD V F C C C+ ++C + + L Sbjct: 63 VLGHEITGEVVEKGSDVELMDIGDLVSVPFNVACGRCRNCKEARSDVCENNLVNPDADL- 121 Query: 137 DGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKI---DDAAPPEKV---CLIGCGFST 190 G F KG + EY +V + + D EK+ LI T Sbjct: 122 -GAFGFDLKGW-------SGGQAEYVLVPYADYMLLKFGDKEQAMEKIKDLTLISDILPT 173 Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 G+ V + VKPGS + G G VG G + GA+ +I D N ++ + G Sbjct: 174 GFHGCV-SAGVKPGSHVYIAGAGPVGRCAAAGARLLGAACVIVGDQNPERLKLLSDAGF- 231 Query: 251 ECISPKDSTKPISEVLSEMTGN-NVGYTFEVIG-------------HLETMIDALASCHM 296 E I ++S P+ + + ++ G V + +G +++L Sbjct: 232 ETIDLRNSA-PLRDQIDQILGKPEVDCGVDAVGFEAHGLGDEANTETPNGALNSLFDVVR 290 Query: 297 NYGTSVVVGVPPSAKMLTYDP------MLLFTGRTWKGCVF--GGLKSRDDVPKLVTE-- 346 G + G+ + + + L G+ W + G+ + + +TE Sbjct: 291 AGGAIGIPGIYVGSDPDPVNKDAGSGRLHLDFGKMWTKSIRIMTGMAPVTNYNRHLTEAI 350 Query: 347 ------FLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLT 385 +L+K ++ V+ + +G+ + G + V+ Sbjct: 351 LWDQMPYLSKVMNI-----EVITLDQAPDGYAKFDKGSPAKFVID 390 >3QWB-A nrPDB Length = 334 Score = 172 bits (435), Expect = 3e-43, Method: Composition-based stats. Identities = 71/362 (19%), Positives = 125/362 (34%), Gaps = 65/362 (17%) Query: 34 FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGV 93 E+ V +E+ IK TG+ + + KG + P ++G EA+G V + G+GV Sbjct: 23 IKYEDYPVPSISEEELLIKNKYTGVNYIESYFRKGIYPCEKPYVLGREASGTVVAKGKGV 82 Query: 94 TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFM 153 T + GD+V ++ Sbjct: 83 TNFEVGDQVA------------------------------------------------YI 94 Query: 154 NTSTFTEY-TVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAA---VKTGKVKPGSTCVV 209 + STF +Y + + V K+ E++ L G A + VK G ++ Sbjct: 95 SNSTFAQYSKISSQGPVMKLPKGTSDEELKLYAAGLLQVLTALSFTNEAYHVKKGDYVLL 154 Query: 210 FGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSE 268 F GGVGL + K GA I + +K + A GA I+ + +VL Sbjct: 155 FAAAGGVGLILNQLLKMKGA-HTIAVASTDEKLKIAKEYGAEYLINASK-EDILRQVLKF 212 Query: 269 MTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRT-WK 327 G V +F+ +G + + + G V G L T + Sbjct: 213 TNGKGVDASFDSVG--KDTFEISLAALKRKGVFVSFGNASGLIPPFSITRLSPKNITLVR 270 Query: 328 GCVFGGLKSRDDVPKLVTEFL----AKKFDLDQLITHVLPFKKISEGFELLNSGQSI-RT 382 ++G + ++ EF +KK ++ I P + + S +++ + Sbjct: 271 PQLYGYIADPEEWKYYSDEFFGLVNSKKLNIK--IYKTYPLRDYRTAAADIESRKTVGKL 328 Query: 383 VL 384 VL Sbjct: 329 VL 330 >2CF5-A nrPDB Length = 357 Score = 159 bits (402), Expect = 2e-39, Method: Composition-based stats. Identities = 77/355 (21%), Positives = 136/355 (38%), Gaps = 34/355 (9%) Query: 28 WEQKQP---FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFPVIVGHEAT 83 W + P S + ++V I+I+ GIC TD H K + S +P++ GHE Sbjct: 13 WAARDPSGILSPYTYTLRETGPEDVNIRIICCGICHTDLHQTKNDLGMSNYPMVPGHEVV 72 Query: 84 GIVESIGEGVTTVKPGD-KVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRF 142 G V +G V+ GD + + C C+ C C + + V +G Sbjct: 73 GEVVEVGSDVSKFTVGDIVGVGCLVGCCGGCSPCERDLEQYCPKKIWSYNDVYINGQ--- 129 Query: 143 TCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVK 202 F + TVV + V KI + E+ + C T Y G + Sbjct: 130 ----------PTQGGFAKATVVHQKFVVKIPEGMAVEQAAPLLCAGVTVYSPLSHFGLKQ 179 Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA-VGATECISPKDSTKP 261 PG + GLGGVG + K+ G + I + K E+A+ +GA + + D K Sbjct: 180 PGLRGGILGLGGVGHMGVKIAKAMG-HHVTVISSSNKKREEALQDLGADDYVIGSDQAKM 238 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLF 321 +++ Y + + + L+ + G +++GV + P+L+ Sbjct: 239 SE------LADSLDYVIDTVPVHHALEPYLSLLKL-DGKLILMGVINNPLQF-LTPLLML 290 Query: 322 TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 + G G +K +++ + K+ L +I V+ ++ FE L Sbjct: 291 GRKVITGSFIGSMKETEEMLEFC-----KEKGLSSII-EVVKMDYVNTAFERLEK 339 >1WLY-A nrPDB Length = 333 Score = 150 bits (380), Expect = 7e-37, Method: Composition-based stats. Identities = 71/381 (18%), Positives = 129/381 (33%), Gaps = 72/381 (18%) Query: 24 AAVLWEQKQP--FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGT----MVSKFPVI 77 AAV+ ++ P F EE++V P +VR++ A G+ D + G +V + P++ Sbjct: 4 AAVIHKKGGPDNFVWEEVKVGSPGPGQVRLRNTAIGVNFLDTYHRAGIPHPLVVGEPPIV 63 Query: 78 VGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 VG EA +VE +G GVT G++V P Sbjct: 64 VGFEAAAVVEEVGPGVTDFTVGERVCTCLPP----------------------------- 94 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCG--FSTGYGAA 195 +++ + + K+ + V L G T Sbjct: 95 -----------------LGAYSQERLYPAEKLIKVPKDLDLDDVHLAGLMLKGMTAQYLL 137 Query: 196 VKTGKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 +T KVKPG ++ GG+G ++ + GA +IG ++K E A +G I+ Sbjct: 138 HQTHKVKPGDYVLIHAAAGGMGHIMVPWARHLGA-TVIGTVSTEEKAETARKLGCHHTIN 196 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 + V G V ++ IG + + C G G Sbjct: 197 Y-STQDFAEVVREITGGKGVDVVYDSIG--KDTLQKSLDCLRPRGMCAAYGHASGVA--- 250 Query: 315 YDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEF---------LAKKFDLDQLITHVLPFK 365 DP+ + +G +F + +E K L + P + Sbjct: 251 -DPIRVVEDLGVRGSLFITRPALWHYMSNRSEIDEGSKCLFDAVKAGVLHSSVAKTFPLR 309 Query: 366 KISEGFELLNSGQSIRTVLTF 386 + + + + Q+I +++ Sbjct: 310 EAAAAHKYMGGRQTIGSIVLL 330 >1QOR-A nrPDB Length = 327 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 68/360 (18%), Positives = 119/360 (33%), Gaps = 60/360 (16%) Query: 27 LWEQKQPFSIEEIEVAP--PKTKEVRIKILATGICRTDDHVIKGTMVSK-FPVIVGHEAT 83 + P ++ +E P P E++++ A GI D ++ G P +G EA Sbjct: 7 FHKHGGPEVLQAVEFTPADPAENEIQVENKAIGINFIDTYIRSGLYPPPSLPSGLGTEAA 66 Query: 84 GIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFT 143 GIV +G GV +K GD+V+ Sbjct: 67 GIVSKVGSGVKHIKAGDRVV---------------------------------------- 86 Query: 144 CKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP 203 + ++ + A + A E+ T Y KT ++KP Sbjct: 87 ------YAQSALGAYSSVHNIIADKAAILPAAISFEQAAASFLKGLTVYYLLRKTYEIKP 140 Query: 204 GSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 + GGVGL K+ GA ++IG K + A+ GA + I+ ++ + Sbjct: 141 DEQFLFHAAAGGVGLIACQWAKALGA-KLIGTVGTAQKAQSALKAGAWQVINYRE-EDLV 198 Query: 263 SEVLSEMTGNNVGYTFEVIG--HLETMIDALA----SCHMNYGTSVVVGVPPSAKMLTYD 316 + G V ++ +G E +D L + V GV +L Sbjct: 199 ERLKEITGGKKVRVVYDSVGRDTWERSLDCLQRRGLMVSFGNSSGAVTGVNLG--ILNQK 256 Query: 317 PMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 L T + +G + + + +L + + +D P K E+L S Sbjct: 257 GSLYVTRPSLQGYITTREELTEASNELFSLIASGVIKVDVAEQQKYPLKDAQRAHEILES 316 >3JYN-A nrPDB Length = 325 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 71/367 (19%), Positives = 126/367 (34%), Gaps = 65/367 (17%) Query: 31 KQPFSIEEIEVAP--PKTKEVRIKILATGICRTDDHVIKGTMVSKF-PVIVGHEATGIVE 87 P +E ++ P P + V ++ A G+ D + G + F P +G E G+VE Sbjct: 11 GGPEVLEYVDFEPEAPGPQAVVVRNKAIGLNFIDTYYRSGLYPAPFLPSGLGAEGAGVVE 70 Query: 88 SIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGK 147 ++G+ VT RF + Sbjct: 71 AVGDEVT----------------------------------------------RFKVGDR 84 Query: 148 PVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTC 207 + ++E V+ E+++ K+ D+ E+ + T +T +VKPG Sbjct: 85 VAYGTGPLGAYSEVHVLPEANLVKLADSVSFEQAAALMLKGLTVQYLLRQTYQVKPGEII 144 Query: 208 VVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVL 266 + GGVG K+ GA ++IG + +K A A+GA E I VL Sbjct: 145 LFHAAAGGVGSLACQWAKALGA-KLIGTVSSPEKAAHAKALGAWETIDY-SHEDVAKRVL 202 Query: 267 SEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFT---- 322 G ++ +G +T + +L S G V G S + + +L Sbjct: 203 ELTDGKKCPVVYDGVG-QDTWLTSLDSVAPR-GLVVSFG-NASGPVSGVNLGILAQKDSV 259 Query: 323 --GRTWKGCVFGGLKSRDDVP-KLVTEFLAKKFDLDQLITHVLPFKKISEG-FELLNSGQ 378 R G ++ + +L + K +D + K ++ EL Sbjct: 260 YVTRPTLGSYANNAQNLQTMADELFDMLASGKLKVDGI--EQYALKDAAKAQIELSARRT 317 Query: 379 SIRTVLT 385 + T+L Sbjct: 318 TGSTILI 324 >4RVS-A nrPDB Length = 329 Score = 138 bits (348), Expect = 4e-33, Method: Composition-based stats. Identities = 66/370 (17%), Positives = 116/370 (31%), Gaps = 62/370 (16%) Query: 29 EQKQPFSIEEIEVAPPKTK--EVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIV 86 E P + ++ P+ E+ IK A G+ D + G + P ++G E G V Sbjct: 9 ETGGPGVLRHVDQPQPQPGHGELLIKAEAIGVNFIDTYFRSGQYPRELPFVIGSEVCGTV 68 Query: 87 ESIGEGVTT----VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRF 142 E++G GVT + GD+V+ Sbjct: 69 EAVGPGVTAADTAISVGDRVVSASA----------------------------------- 93 Query: 143 TCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVK 202 + E+ S AK+ D E T + VK Sbjct: 94 ------------NGAYAEFCTAPASLTAKVPDDVTSEVAASALLKGLTAHYLLKSVYPVK 141 Query: 203 PGSTCVVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-PKDSTK 260 G T +V G GGVGL + G R+I +K + + GA + P+D+ + Sbjct: 142 RGDTVLVHAGAGGVGLILTQWATHLGV-RVITTVSTAEKAKLSKDAGADVVLDYPEDAWQ 200 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 V G V ++ +G T DA + GT + G L Sbjct: 201 FAGRVRELTGGTGVQAVYDGVGA--TTFDASLASLAVRGTLALFGAASGPVPPVDPQRLN 258 Query: 321 FTGRTW--KGCVFGGLKSRDDVPKLVTEF--LAKKFDLDQLITHVLPFKKISEGFELLNS 376 G + + +F ++ ++ E + + P + L + Sbjct: 259 AAGSVYLTRPSLFHFTRTGEEFSWRAAELFDAIGNEAITVAVGGRYPLADALRAHQDLEA 318 Query: 377 GQSIRTVLTF 386 +++ +V+ Sbjct: 319 RKTVGSVVLL 328 >4J6F-A nrPDB Length = 382 Score = 134 bits (336), Expect = 8e-32, Method: Composition-based stats. Identities = 63/368 (17%), Positives = 116/368 (31%), Gaps = 58/368 (15%) Query: 37 EEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK-----------------FPVIVG 79 ++ V P EV IK+ A G+ TD V +G ++ FP I G Sbjct: 52 RDVPVPAPAAGEVLIKVTACGMNNTDVWVREGAYGTEDDPSAVSTWRRHGNTLTFPRIQG 111 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 + G + ++GEGV + G++V+ F R+ Sbjct: 112 TDTVGHIVAVGEGVDRARIGERVMVDFSIYNRD--------------------------- 144 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + + EY + + + ++ C + TG ++ Sbjct: 145 -DDSLADIDYMGHGRDGGYAEYMALPAENAHVVATDLTDIELATFCCAYLTG-ERMLERA 202 Query: 200 KVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDS 258 ++ G T +V G GGVG ++I ++ GA I K + +GA + + Sbjct: 203 RLAAGETVLVTGASGGVGSAIIQLARARGAVPIAVAG--PGKEAAMLDIGAQAVV-TRGQ 259 Query: 259 TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPM 318 V + G + +++G + + L G G + Sbjct: 260 GDLAEAVEAASGGRPIDVVADLVGGP--LFNDLLKILRPEGRYTTAGAIAGPVVQLDLRT 317 Query: 319 LLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEG-FELLNSG 377 + G G R D +LV KK L+ V P + + + Sbjct: 318 MYLKQLELHGSSQGS---RADFRRLVRYIEEKKI--RPLVGGVYPLSEFHRAQTDFMAKN 372 Query: 378 QSIRTVLT 385 + V+ Sbjct: 373 FVGKLVVV 380 >2OBY-A nrPDB Length = 338 Score = 134 bits (336), Expect = 8e-32, Method: Composition-based stats. Identities = 65/379 (17%), Positives = 120/379 (31%), Gaps = 67/379 (17%) Query: 24 AAVLWEQKQP--FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPV--IVG 79 A + P ++E+ P EV +K+ A+ + R D +G I+G Sbjct: 9 AVHFDKPGGPENLYVKEVAKPSPGEGEVLLKVAASALNRADLMQRQGQYDPPPGASNILG 68 Query: 80 HEATGIVESIGEGVT-TVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 EA+G V +G G K GD + L Sbjct: 69 LEASGHVAELGPGCQGHWKIGDTAMALLPG------------------------------ 98 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 +Y V E + I + + I + T + Sbjct: 99 -----------------GGQAQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLV 141 Query: 199 GKVKPGSTCVVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 G V+ G ++ GL GVG + I + AGA ++ ++ K + A +GA + K Sbjct: 142 GNVQAGDYVLIHAGLSGVGTAAIQLTRMAGAIPLV-TAGSQKKLQMAEKLGAAAGFNYKK 200 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK-MLTYD 316 L G V + IG + + +C G V+ G+ Sbjct: 201 -EDFSEATLKFTKGAGVNLILDCIGG--SYWEKNVNCLALDGRWVLYGLMGGGDINGPLF 257 Query: 317 PMLLFTGRTWKGCVFGGLKSR------DDVPKLVTEFLA--KKFDLDQLITHVLPFKKIS 368 LLF + + ++ + + + + L ++ + P +I Sbjct: 258 SKLLFKRGSLITSLLRSRDNKYKQMLVNAFTEQILPHFSTEGPQRLLPVLDRIYPVTEIQ 317 Query: 369 EGFELLNSGQSI-RTVLTF 386 E + + + ++I + VL Sbjct: 318 EAHKYMEANKNIGKIVLEL 336 >2VCY-A nrPDB Length = 344 Score = 129 bits (325), Expect = 2e-30, Method: Composition-based stats. Identities = 71/382 (18%), Positives = 133/382 (34%), Gaps = 66/382 (17%) Query: 21 KCKAAVLWEQKQPFS---IEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMV--SKFP 75 + +A V P ++ +E+A + +VR+K+LA I +D ++I+G + P Sbjct: 13 RVRALVYGHHGDPAKVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGLLPELP 72 Query: 76 VIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVL 135 + G+E V ++G VT +KPGD VIP Sbjct: 73 AVGGNEGVAQVVAVGSNVTGLKPGDWVIPA------------------------------ 102 Query: 136 ADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAA 195 T+ V E ++ ++ P + +G T Y Sbjct: 103 ----------------NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRML 146 Query: 196 VKTGKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKD--KF-EKAMAVGATE 251 + +++PG + + GVG +VI + G I + D K ++ ++GA Sbjct: 147 MDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQKLSDRLKSLGAEH 206 Query: 252 CISPKDSTKP-ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSA 310 I+ ++ +P + +M +G + L GT V G Sbjct: 207 VITEEELRRPEMKNFFKDMP--QPRLALNCVGGKSSTE--LLRQLARGGTMVTYGGMAKQ 262 Query: 311 KMLTYDPMLLFTGRTWKGCVFGGLK---SRDDVPKLVTEF--LAKKFDLDQLITHVLPFK 365 ++ +L+F +G K S D +L+ L ++ L +P + Sbjct: 263 PVVASVSLLIFKDLKLRGFWLSQWKKDHSPDQFKELILTLCDLIRRGQLTAPACSQVPLQ 322 Query: 366 KISEGFEL-LNSGQSIRTVLTF 386 E + S + +LT Sbjct: 323 DYQSALEASMKPFISSKQILTM 344 >3FBG-A nrPDB Length = 346 Score = 129 bits (324), Expect = 2e-30, Method: Composition-based stats. Identities = 56/293 (19%), Positives = 92/293 (31%), Gaps = 65/293 (22%) Query: 27 LWEQKQPFSIEE--------IEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIV 78 +QPF + + +++ PK E+ +KI + + D VSK P ++ Sbjct: 5 AIGFEQPFKLSDGNLFKTFNLDIPEPKVHEILVKIQSISVNPVDTKQR-LMDVSKAPRVL 63 Query: 79 GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 G +A G+VES+G VT GD V P Sbjct: 64 GFDAIGVVESVGNEVTMFNQGDIVYYSGSPD----------------------------- 94 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 + EY +++E VAK E+ + T Y Sbjct: 95 ---------------QNGSNAEYQLINERLVAKAPKNISAEQAVSLPLTGITAYETLFDV 139 Query: 199 GKVK------PGSTCVVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 + G T ++ G GGVG K+ G R+I + E +GA Sbjct: 140 FGISRNRNENEGKTLLIINGAGGVGSIATQIAKAYGL-RVITTASRNETIEWTKKMGADI 198 Query: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVV 304 ++ K+S + V Y F + + D + G + Sbjct: 199 VLNHKES---LLNQFKTQGIELVDYVF-CTFNTDMYYDDMIQLVKPRGHIATI 247 >3HZZ-A nrPDB Length = 467 Score = 128 bits (322), Expect = 4e-30, Method: Composition-based stats. Identities = 65/420 (15%), Positives = 125/420 (29%), Gaps = 88/420 (20%) Query: 1 MFAEIQIQDKDRMGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICR 60 MFA ++ +DKD ++ ++E+ V E + ++A+ + Sbjct: 61 MFAGLETRDKD------------------PRKSIHLDEVPVPELGPGEALVAVMASSVNY 102 Query: 61 TDDHV-------------IKGTMVS-----KFPV-IVGHEATGIVESIGEGVTTVKPGDK 101 G + P I+G + G+V G GV +PGD+ Sbjct: 103 NSVWTSIFEPVSTFAFLERYGKLSPLTKRHDLPYHIIGSDLAGVVLRTGPGVNAWQPGDE 162 Query: 102 VIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEY 161 V+ C+ ++ D T + + N E Sbjct: 163 VVA------------------HCLSVELESPDGHDD--TMLDPEQRIWGFETNFGGLAEI 202 Query: 162 TVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAV--KTGKVKPGSTCVVFGL-GGVGLS 218 +V + + E+ G ST Y V +K G +++G GG+G Sbjct: 203 ALVKTNQLMPKPKHLTWEEAAAPGLVNSTAYRQLVSRNGAAMKQGDNVLIWGASGGLGSY 262 Query: 219 VIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI----------------SPKDSTKPI 262 + GA+ I + + K E ++GA I PK+ + Sbjct: 263 ATQFALAGGANPICVVS-SPQKAEICRSMGAEAIIDRNAEGYKFWKDEHTQDPKEWKRFG 321 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFT 322 + G ++ FE G A GT + L + Sbjct: 322 KRIRELTGGEDIDIVFEHPGRE--TFGASVYVTRKGGTITTCASTSGYMHEYDNRYLWMS 379 Query: 323 GRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF----ELLNSGQ 378 + G F + + +L+ K + ++ ++ + L+ G+ Sbjct: 380 LKRIIGSHFANYREAYEANRLIA-----KGKIHPTLSKTYSLEETGQAAYDVHRNLHQGK 434 >4A10-A nrPDB Length = 447 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 64/387 (16%), Positives = 122/387 (31%), Gaps = 68/387 (17%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDD----------------HVI 66 K + ++ + E+ + EV + ++A+ I + Sbjct: 39 KGVADKDVRKSLRLGEVPMPELAPDEVLVAVMASSINYNTVWSAMFEPIPTFHFLKQNAR 98 Query: 67 KGTMVSKFP---VIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNL 123 +G ++ ++G + +G+V G GV KPGD VI Sbjct: 99 QGGWATRHDQPYHVLGSDCSGVVVRTGIGVRRWKPGDHVIV------------------H 140 Query: 124 CIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCL 183 D DG + + N EY VV S + E+ + Sbjct: 141 PAHVDEQEPATHGDGMLG--TEQRAWGFETNFGGLAEYGVVRASQLLPKPAHLTWEEAAV 198 Query: 184 IGCGFSTGYGAAV--KTGKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDK 240 T Y V + ++K G +++G GG+G I K+ G + + + K Sbjct: 199 SPLCAGTAYRMLVSDRGAQMKQGDIVLIWGASGGLGSYAIQFVKNGGGIPVAVVS-SAQK 257 Query: 241 FEKAMAVGATECISPKD-------STKP---------ISEVLSEMTGNNVGYTFEVIGHL 284 A+G I+ + + P +++++ E G FE G + Sbjct: 258 EAAVRALGCDLVINRAELGITDDIADDPRRVVETGRKLAKLVVEKAGREPDIVFEHTGRV 317 Query: 285 ETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP-MLLFTGRTWKGCVFGGLKSRDDVPKL 343 + + GT V G S + T+D L + G + + +L Sbjct: 318 TFGLSVI--VARRGGTVVTCG-SSSGYLHTFDNRYLWMKLKKIVGSHGANHEEQQATNRL 374 Query: 344 VTEFLAKKFDLDQLITHVLPFKKISEG 370 + ++ V P + +E Sbjct: 375 FESGA-----VVPAMSAVYPLAEAAEA 396 >4DVJ-A nrPDB Length = 363 Score = 117 bits (294), Expect = 6e-27, Method: Composition-based stats. Identities = 59/356 (16%), Positives = 118/356 (33%), Gaps = 69/356 (19%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSIE------EIEVAPPKTKEVRIKILATGICRTDDHVI 66 +GT + AV + + P + + E+ P ++ +++ A + D V Sbjct: 13 LGTENLYFQSMKAVGYNKPAPITDDASLLDIELPKPAPAGHDILVEVKAVSVNPVDYKVR 72 Query: 67 KGTMVSKFPV-IVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCI 125 + T ++G++A GIV ++G VT +PGD+V Sbjct: 73 RSTPPDGTDWKVIGYDAAGIVSAVGPDVTLFRPGDEVFYAGSI----------------- 115 Query: 126 RSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIG 185 + T E+ +VDE V + + + Sbjct: 116 ---------------------------IRPGTNAEFHLVDERIVGRKPKTLDWAEAAALP 148 Query: 186 CGFSTGYGAAVKTGKVK---PGSTCVVF---GLGGVGLSVIMGCKSAGASRIIGIDLNKD 239 T + A V PG+ + G GGVG + + +I + Sbjct: 149 LTSITAWEAFFDRLDVNKPVPGAAPAILIVGGAGGVGSIAVQIARQRTDLTVIATASRPE 208 Query: 240 KFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYG 299 E ++GA I D +KP++ ++ + + F H + +A G Sbjct: 209 TQEWVKSLGAHHVI---DHSKPLAAEVAALGLGAPAFVFSTT-HTDKHAAEIADLIAPQG 264 Query: 300 TSVVVGVPPSAKMLTY--DPMLLFTGRTWKGCVFGG------LKSRDDVPKLVTEF 347 ++ P + ++ + + + + +FG + +DV +LV E Sbjct: 265 RFCLIDDPSAFDIMLFKRKAVSIHHELMFTRPMFGTPDMSEQGRLLNDVSRLVDEG 320 >3SLK-A nrPDB Length = 795 Score = 115 bits (289), Expect = 3e-26, Method: Composition-based stats. Identities = 63/347 (18%), Positives = 107/347 (30%), Gaps = 59/347 (17%) Query: 42 APPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDK 101 AP EVRI + A G+ D + G +G E G+V G GVT + PGD+ Sbjct: 234 APLGDGEVRIAMRAAGVNFRDALIALGMYPGV--ASLGSEGAGVVVETGPGVTGLAPGDR 291 Query: 102 VIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEY 161 V+ + F Sbjct: 292 VMGMIPKA------------------------------------------------FGPL 303 Query: 162 TVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVF-GLGGVGLSVI 220 V D V +I + + F T Y A V ++PG + +V GGVG++ I Sbjct: 304 AVADHRMVTRIPAGWSFARAASVPIVFLTAYYALVDLAGLRPGESLLVHSAAGGVGMAAI 363 Query: 221 MGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEV 280 + GA + ++DK++ A+ + S + + L G V Sbjct: 364 QLARHLGAE--VYATASEDKWQ-AVELSREHLASSRTCDFE-QQFLGATGGRGVDVVLNS 419 Query: 281 IGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDV 340 + DA G + +G + V G + ++ Sbjct: 420 LAGE--FADASLRMLPRGGRFLELGKTDVRDPVEVADAHPGVSYQAFDTVEAGPQRIGEM 477 Query: 341 PKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSI-RTVLTF 386 + E + L+ L ++ E L+ + + + VLT Sbjct: 478 LHELVELFEGRV-LEPLPVTAWDVRQAPEALRHLSQARHVGKLVLTM 523 >2VN8-A nrPDB Length = 375 Score = 115 bits (288), Expect = 3e-26, Method: Composition-based stats. Identities = 73/415 (17%), Positives = 129/415 (31%), Gaps = 98/415 (23%) Query: 13 MGTAGKVIKCKAAVLWEQKQPFSI---EEIEVAPPK-TKEVRIKILATGICRTDDHVIKG 68 +GT + A V+ + + + + + + EV +K+ A + D ++ G Sbjct: 13 LGTENLYFQSMAWVIDKYGKNEVLRFTQNMMMPIIHYPNEVIVKVHAASVNPIDVNMRSG 72 Query: 69 ----------------TMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRE 112 +FP+ +G + +G+V G V KPGD+V P Sbjct: 73 YGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECGLDVKYFKPGDEVWAAVPPW--- 129 Query: 113 CNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKI 172 T +E+ VV + V+ Sbjct: 130 -----------------------------------------KQGTLSEFVVVSGNEVSHK 148 Query: 173 DDAAPPEKVCLIGCGFSTGYGAAVKTGKVK----PGSTCVVFGL-GGVGLSVIMGCKSAG 227 + + + T + A K G + G ++ G GGVG I K+ Sbjct: 149 PKSLTHTQAASLPYVALTAWSAINKVGGLNDKNCTGKRVLILGASGGVGTFAIQVMKAWD 208 Query: 228 ASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETM 287 A + + E +GA + I K + + E L + + + +G Sbjct: 209 A-HVTAVCSQDAS-ELVRKLGADDVIDYKSGS--VEEQLKSL--KPFDFILDNVGGSTET 262 Query: 288 IDALASCHMNYGTSVVVGVPP--SAKMLTYDPMLLFTGRT---------WKGC------V 330 + T V + P + L +L TG T WKG Sbjct: 263 WAPDFLKKWSGATYVTLVTPFLLNMDRLGIADGMLQTGVTVGSKALKHFWKGVHYRWAFF 322 Query: 331 FGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQS-IRTVL 384 DD+ +LV + +I PF K+ E F + G + +TV+ Sbjct: 323 MASGPCLDDIAELVDAG-----KIRPVIEQTFPFSKVPEAFLKVERGHARGKTVI 372 >4Y1B-A nrPDB Length = 425 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 70/413 (16%), Positives = 138/413 (33%), Gaps = 67/413 (16%) Query: 6 QIQDKDRMGTAGKVIKCKAAVLWEQKQP---FSIEEIEVAPPKTKEVRIKILATGICRT- 61 ++ D +GTA K + +P F E ++V P +V +K++A G+ Sbjct: 27 ELGDAPPLGTAPKQMYASLIRQERYGRPVDAFRTEVVDVPPVGPGQVLVKVMAAGVNYNN 86 Query: 62 ---------DDHVIKGTMVSKFPV-IVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCR 111 D + + I G + +GIV ++G+GV +KPG +V+ L Sbjct: 87 VWAALGEPLDVIAARQKQGATEDFHIGGSDLSGIVWAVGDGV-RLKPGAEVVVL------ 139 Query: 112 ECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAK 171 ACR D + + + + + + N +F ++ VVDE Sbjct: 140 ---ACR---------WDESAQDIRLGADPVTSSTQRVWGYEENYGSFAQFAVVDEYMCHP 187 Query: 172 IDDAAPPEKVCLIGCGFSTGYGAA--VKTGKVKPGSTCVVF-GLGGVGLSVIMGCKSAGA 228 +T Y + V+PG +++ G GG+G I + G Sbjct: 188 KPQRLSWAAASCYMATAATAYRQLFGWEPHTVRPGDPVLIWGGAGGLGSIAIQLVRHVGG 247 Query: 229 SRIIGIDLNKDKFEKAMAVGATECISPKD-----------STKPISEVLSEMTGNN---- 273 + + ++++ E M +GA I ++ + + + L Sbjct: 248 IPVAVVS-SEERGEFCMRLGAKGWIDRREFDHWGRLPDTTDEEAMKQWLDGARAFGRRFW 306 Query: 274 --------VGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRT 325 E G I N G V+ G L + Sbjct: 307 EVLGERRAPRIVLEHSGA--DTIPTSIYMADNAGMVVICGGTTGYNGDVDLRFLWMRQKR 364 Query: 326 WKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 378 +G + ++ +L+ + +D ++ F++I +L++ Q Sbjct: 365 LQGSHAASAREAREITRLIDQGA-----IDPCLSRTFGFEEIGLAHQLIHDNQ 412 >2WEK-A nrPDB Length = 341 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 86/277 (31%), Gaps = 59/277 (21%) Query: 37 EEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS--KFPVIVGHEATGIVESIG-EGV 93 + V P ++ ++ G+ +D + G K P +G E G V ++G Sbjct: 23 RDCPVPLPGDGDLLVRNRFVGVNASDINYSAGRYDPSVKPPFDIGFEGIGEVVALGLSAS 82 Query: 94 TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFM 153 G V +M Sbjct: 83 ARYTVGQAVA------------------------------------------------YM 94 Query: 154 NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVF-GL 212 +F EYTVV S + P + + +T Y + + G + G +V Sbjct: 95 APGSFAEYTVVPASIATPVPSVKP--EYLTLLVSGTTAYISLKELGGLSEGKKVLVTAAA 152 Query: 213 GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGN 272 GG G + K A +IG + +K ++G I+ K T+P+ VL + Sbjct: 153 GGTGQFAMQLSKKA-KCHVIGTCSSDEKSAFLKSLGCDRPINYK--TEPVGTVLKQEYPE 209 Query: 273 NVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPS 309 V +E +G M D G +V+G Sbjct: 210 GVDVVYESVGG--AMFDLAVDALATKGRLIVIGFISG 244 >5A3V-A nrPDB Length = 329 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 58/359 (16%), Positives = 100/359 (27%), Gaps = 67/359 (18%) Query: 38 EIEVAPPKTKEVRIKILATGICRTDDHVIKGT----MVSKFPVIVGHEATGIVESIGEGV 93 ++ V PK+ EV +K+ AT + D + KG + KFP I + G V +G GV Sbjct: 25 QVPVPTPKSNEVCLKLEATSLNPVDWKIQKGMIRPFLPRKFPCIPATDVAGEVVEVGSGV 84 Query: 94 TTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFM 153 K GDKV+ + + Sbjct: 85 KNFKAGDKVVAVLS--------------------------------------------HL 100 Query: 154 NTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKP---GST--CV 208 E+ V E K + + T A +K G + Sbjct: 101 GGGGLAEFAVATEKLTVKRPQEVGAAEAAALPVAGLTALQALTNPAGLKLDGTGKKANIL 160 Query: 209 VFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLS 267 V GGVG + K A A + E ++GA E + K P L Sbjct: 161 VTAASGGVGHYAVQLAKLANA-HVTAT-CGARNIEFVKSLGADEVLDYK---TPEGAALK 215 Query: 268 EMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSV-VVGVPPSAKMLTYDPMLLFTGRTW 326 +G + G + + P + + + + Sbjct: 216 SPSGKKYDAVVHCANGIP--FSVFEPNLSENGKVIDITPGPNAMWTYAVKKITMSKKQLV 273 Query: 327 KGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLT 385 + ++ + + LV E K + P K + + G + ++ Sbjct: 274 PLLLIPKAENLEFMVNLVKEGKVKTVIDSK-----HPLSKAEDAWAKSIDGHATGKIIV 327 >3TQH-A nrPDB Length = 321 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 59/366 (16%), Positives = 112/366 (30%), Gaps = 69/366 (18%) Query: 28 WEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKG------TMVSKFPVIVGHE 81 + + + + + ++ IK+ A + D G + + P +G++ Sbjct: 15 FGPPKVLKLVDTPTPEYRKNQMLIKVHAASLNPIDYKTRNGSGFVAKKLKNNLPSGLGYD 74 Query: 82 ATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTR 141 +G V +G V V GDKV+ + C C Sbjct: 75 FSGEVIELGSDVNNVNIGDKVMGIAGFPDHPC--C------------------------- 107 Query: 142 FTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKV 201 + EY ++ + + + + T A+ +V Sbjct: 108 ----------------YAEYVCASPDTIIQKLEKLSFLQAASLPTAGLTALQ-ALNQAEV 150 Query: 202 KPGSTCVVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 K G ++ G GGVG I K G + +K A+GA +CI+ + Sbjct: 151 KQGDVVLIHAGAGGVGHLAIQLAKQKG--TTVITTASKRNHAFLKALGAEQCINYHEEDF 208 Query: 261 PISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 ++ V +++G + C G V V + +++ Sbjct: 209 LLA------ISTPVDAVIDLVGGDVGIQS--IDCLKETGCIVSVPTITAGRVIEV----- 255 Query: 321 FTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSI 380 + FG LK + L + L I+ + + ELL +G + Sbjct: 256 --AKQKHRRAFGLLKQFNIEELHYLGKLVSEDKLRIEISRIFQLSEAVTAHELLETGH-V 312 Query: 381 RTVLTF 386 R L F Sbjct: 313 RGKLVF 318 >4EYE-A nrPDB Length = 342 Score = 112 bits (279), Expect = 3e-25, Method: Composition-based stats. Identities = 69/372 (18%), Positives = 117/372 (31%), Gaps = 62/372 (16%) Query: 23 KAAVLWEQKQP--FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSK--FPVIV 78 KA P ++E V + + A G+C D + KG K P + Sbjct: 23 KAIQAQSLSGPEGLVYTDVETPGAGPNVVVVDVKAAGVCFPDYLMTKGEYQLKMEPPFVP 82 Query: 79 GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 G E G+V S EG + +KPGD+V+ Sbjct: 83 GIETAGVVRSAPEG-SGIKPGDRVMA---------------------------------- 107 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 F + E V S++ + + + T Y A + Sbjct: 108 -------------FNFIGGYAERVAVAPSNILPTPPQLDDAEAVALIANYHTMYFAYARR 154 Query: 199 GKVKPGSTCVVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 G+++ G T +V GG+G + I K GA ++I + E +VGA + ++ Sbjct: 155 GQLRAGETVLVLGAAGGIGTAAIQIAKGMGA-KVIAVVNRTAATEFVKSVGADIVLPLEE 213 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP 317 V G V + IG D + G +VVG Sbjct: 214 GW--AKAVREATGGAGVDMVVDPIGGPA--FDDAVRTLASEGRLLVVGFAAGGIPTIKVN 269 Query: 318 MLLFTGRTWKGCVFGGL-KSRDDVPKLVTEFLAKKFD--LDQLITHVLPFKKISEGFELL 374 LL + G +G ++ D L K + ++ +P + + + Sbjct: 270 RLLLRNASLIGVAWGEFLRTHADYLYETQAGLEKLVAEGMRPPVSARIPLSEGRQALQDF 329 Query: 375 NSGQ-SIRTVLT 385 G+ + VL Sbjct: 330 ADGKVYGKMVLV 341 >4A27-A nrPDB Length = 349 Score = 111 bits (277), Expect = 5e-25, Method: Composition-based stats. Identities = 63/393 (16%), Positives = 124/393 (31%), Gaps = 86/393 (21%) Query: 23 KAAVLWEQKQ--PFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM--VSKFPVIV 78 +A VL + + P+ E++I++ A G+ D V +G + K P++ Sbjct: 5 RAVVLAGFGGLNKLRLFRKAMPEPQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVP 64 Query: 79 GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 G E +GIVE++G+ V + GD+V+ Sbjct: 65 GFECSGIVEALGDSVKGYEIGDRVMA---------------------------------- 90 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKT 198 F+N + + E V KI D + F T Y + Sbjct: 91 -------------FVNYNAWAEVVCTPVEFVYKIPDDMSFSEAAAFPMNFVTAYVMLFEV 137 Query: 199 GKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD 257 ++ G + +V GGVG +V C + + +A+ T Sbjct: 138 ANLREGMSVLVHSAGGGVGQAVAQLCSTV--PNVTVFGTASTFKHEAIKDSVTHLFD--R 193 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP--SAKMLTY 315 + + EV ++ V + + T S GT ++ G + + ++ Sbjct: 194 NADYVQEV-KRISAEGVDIVLDCLCGDNTGK--GLSLLKPLGTYILYGSSNMVTGETKSF 250 Query: 316 DPM--------------LLFTGRTWKGCVFGGLKSRDD--------VPKLVTEFLAKKFD 353 L + G L + V KL+ + KK Sbjct: 251 FSFAKSWWQVEKVNPIKLYEENKVIAGFSLLNLLFKQGRAGLIRGVVEKLIGLYNQKKI- 309 Query: 354 LDQLITHVLPFKKISEGFELLN-SGQSIRTVLT 385 ++ + +++ E + ++ G + +L Sbjct: 310 -KPVVDSLWALEEVKEAMQRIHDRGNIGKLILD 341 >4IDE-A nrPDB Length = 332 Score = 109 bits (271), Expect = 3e-24, Method: Composition-based stats. Identities = 65/354 (18%), Positives = 113/354 (31%), Gaps = 74/354 (20%) Query: 39 IEVAPPKTKEVRIKILATGICRTDDHVIKG---TMVSKFPVIVGHEATGIVESIGEGVTT 95 + V K +V IK++A + D G S P I G++ G+V +G VT Sbjct: 45 VAVPEIKEDQVLIKVVAASLNPVDFKRALGYFKDTDSPLPTIPGYDVAGVVVKVGSQVTK 104 Query: 96 VKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNT 155 K GD+V + + Sbjct: 105 FKVGDEVYGDLNET--------------------------------------ALVNPTRF 126 Query: 156 STFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGV 215 + EYT DE +A + + T ++ ++ G + +V G G Sbjct: 127 GSLAEYTAADERVLAHKPKNLSFIEAASLPLAIETA-HEGLERAELSAGKSVLVLGGAGG 185 Query: 216 GL-SVIMGCKSA-GASRIIGIDLNKDKFEKAMAVGATECISP-KDSTKPISEVLSEMTGN 272 +I K GAS++ K K + +GA I K++ + + E Sbjct: 186 VGTHIIQLAKHVFGASKVAATASTK-KLDLLRTLGADLAIDYTKENFEDLPEKF------ 238 Query: 273 NVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFG 332 ++ +G + + A+ G V + P + + + T KG V Sbjct: 239 --DVVYDAVGETDKAVKAV----KEGGKVVTIVGPATPPAILFV-------LTSKGSVLE 285 Query: 333 GLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLTF 386 LK + + K T PF K+ E F L S ++ V+ + Sbjct: 286 KLKPYLE---------SGKVKPVLDPTSPYPFTKVVEAFGYLESSRATGKVVVY 330 >3B70-A nrPDB Length = 371 Score = 105 bits (263), Expect = 2e-23, Method: Composition-based stats. Identities = 63/371 (16%), Positives = 115/371 (30%), Gaps = 72/371 (19%) Query: 35 SIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIVGHEATGIVESIGEGVT 94 +V +++ A I +D + G + + +G + G V ++G VT Sbjct: 25 VWNAAPCPMLPRDQVYVRVEAVAINPSDTKMR-GQFATPWAF-LGTDYAGTVVAVGSDVT 82 Query: 95 TVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMN 154 ++ GD+V C + Sbjct: 83 HIQVGDRVYGAQNEMC---------------------------------------PRTPD 103 Query: 155 TSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGST-------- 206 F++YTV AKI E+ + G ST A G P + Sbjct: 104 QGAFSQYTVTRGRVWAKIPKGLSFEQAAALPAGISTAGLAMKLLGLPLPSPSADQPPTHS 163 Query: 207 ----CVVFGLG-GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP 261 +V+G + + +G I + F+ A + GA E + Sbjct: 164 KPVYVLVYGGSTATATVTMQMLRLSGYIPIA--TCSPHNFDLAKSRGAEEVFDYRAPN-- 219 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKML-------- 313 +++ + T NN+ Y + I ++E+ A+ G V + P Sbjct: 220 LAQTIRTYTKNNLRYALDCITNVESTTFCFAAIGRAGGHYVSLNPFPEHAATRKMVTTDW 279 Query: 314 TYDPMLLFTGRTWKGCV-FGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP-----FKKI 367 T P + G TW G + + + + + +L+ H L F I Sbjct: 280 TLGPTIFGEGSTWPAPYGRPGSEEERQFGEDLWRIAGQLVEDGRLVHHPLRVVQGGFDHI 339 Query: 368 SEGFELLNSGQ 378 +G EL+ G+ Sbjct: 340 KQGMELVRKGE 350 >2CDC-A nrPDB Length = 366 Score = 103 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 62/392 (15%), Positives = 128/392 (32%), Gaps = 56/392 (14%) Query: 23 KAAVLWEQKQPFSIEEI-EVAPPKTKEVRIKILATGICRTDDHVIKGTMV-SKFP----- 75 KA ++ ++++ E +++I+ + GIC D ++ G + S P Sbjct: 2 KAIIVKPPNAGVQVKDVDEKKLDSYGKIKIRTIYNGICGADREIVNGKLTLSTLPKGKDF 61 Query: 76 VIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVL 135 +++GHEA G+VE G GD V+P+ C C C + C + G+ Sbjct: 62 LVLGHEAIGVVEESYHG---FSQGDLVMPVNRRGCGICRNCLVGRPDFCETGEFGEAGIH 118 Query: 136 -ADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGA 194 DG R D + KI + E + ++ + + Sbjct: 119 KMDGFMREWWYD------------------DPKYLVKIPKSI--EDIGILAQPLADIEKS 158 Query: 195 AVKTGKVKPG-------------STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKF 241 + +V+ +V G G +G+ + ++ G + + Sbjct: 159 IEEILEVQKRVPVWTCDDGTLNCRKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEV 218 Query: 242 EK-AMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGT 300 E+ + T + + + + + + G ++ + G Sbjct: 219 EQTVIEETKTNYYNSSNGYDKLKDSV-----GKFDVIIDATGADVNILGNVIPLLGRNGV 273 Query: 301 SVVVGVPPSAK-MLTYDPM--LLFTGRTWKGCVFG-GLKSRDDVPKLVTEFLAKKFDLDQ 356 + G S L Y + ++ T +T G V G + V L + Sbjct: 274 LGLFGFSTSGSVPLDYKTLQEIVHTNKTIIGLVNGQKPHFQQAVVHLASWKTLYPKAAKM 333 Query: 357 LITHVLPFKKISEGFELLNSGQ--SIRTVLTF 386 LIT + E ++L + I+ + + Sbjct: 334 LITKTVSINDEKELLKVLREKEHGEIKIRILW 365 >2VWH-A nrPDB Length = 357 Score = 101 bits (251), Expect = 7e-22, Method: Composition-based stats. Identities = 74/382 (19%), Positives = 134/382 (35%), Gaps = 47/382 (12%) Query: 23 KAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFP-----VI 77 KA + + + E P++ E ++ L G+ TD VI G FP ++ Sbjct: 2 KAIAVKRGEDRPVVIEKPRPEPESGEALVRTLRVGVDGTDHEVIAGGHG-GFPEGEDHLV 60 Query: 78 VGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLAD 137 +GHEA G+V T ++ GD V+P + R + D Sbjct: 61 LGHEAVGVVVD--PNDTELEEGDIVVPTVR------RPPASGTNEYFERDQP---DMAPD 109 Query: 138 GTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAP-----PEKVCLIGCGFSTGY 192 G + +G H +E+ E + +I + E + + Y Sbjct: 110 GM--YFERGIVGAH----GYMSEFFTSPEKYLVRIPRSQAELGFLIEPISITEKALEHAY 163 Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKS--AGASRIIGIDLNKD---KFEKAMAV 247 A+ P S+ V G G +GL + K G + + + + Sbjct: 164 -ASRSAFDWDP-SSAFVLGNGSLGLLTLAMLKVDDKGYENLYCLGRRDRPDPTIDIIEEL 221 Query: 248 GATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVP 307 AT S + + + +V +M + +E G + I ++ + N G ++GVP Sbjct: 222 DATYVDSRQTPVEDVPDVYEQM-----DFIYEATGFPKHAIQSVQALAPN-GVGALLGVP 275 Query: 308 PSAKMLTYDPMLLFTGRTW-KGCVFGGLKSRDDVPKLVTEFLAK--KFDLDQLITHVLPF 364 S D + G + S + + T K K+ L+ L+T V P Sbjct: 276 -SDWAFEVDAGAFHREMVLHNKALVGSVNSHVEHFEAATVTFTKLPKWFLEDLVTGVHPL 334 Query: 365 KKISEGFELLNSGQSIRTVLTF 386 + F+ + +I+T + F Sbjct: 335 SEFEAAFD--DDDTTIKTAIEF 354 >5LB9-A nrPDB Length = 385 Score = 82.8 bits (203), Expect = 2e-16, Method: Composition-based stats. Identities = 59/388 (15%), Positives = 107/388 (27%), Gaps = 77/388 (19%) Query: 19 VIKCKAAVLWEQKQP--------FSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTM 70 +I +A + + +P F I++ +A EV +K L + + +D + I+G Sbjct: 22 MITAQAVLYTQHGEPKDVLFTQSFEIDDDNLA---PNEVIVKTLGSPVNPSDINQIQGVY 78 Query: 71 VSKF----------PVIV-GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNP 119 SK P G+E V +G V++++ GD VIP Sbjct: 79 PSKPAKTTGFGTTEPAAPCGNEGLFEVIKVGSNVSSLEAGDWVIPS-------------- 124 Query: 120 DGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPE 179 + A G K + Sbjct: 125 ------HVNFGTWRTHALGNDDDFIKLPNPAQSKANGK---------------PNGLTIN 163 Query: 180 KVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLG--GVGLSVIMGCKSAGASRIIGIDLN 237 + I Y K+ PG + G VG K + I I Sbjct: 164 QGATISVNPLVAYLMLTHYVKLTPGKDWFIQNGGTSAVGKYASQIGKLLNFNSISVIRDR 223 Query: 238 K---DKFEKAMAVGATECI-----SPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMID 289 + +GAT+ I + ++ I E + + +G +G + Sbjct: 224 PNLDEVVASLKELGATQVITEDQNNSREFGPTIKEWIKQ-SGGEAKLALNCVGGKSST-- 280 Query: 290 ALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLA 349 +A N G + G +++ P+ + T ++ K E Sbjct: 281 GIARKLNNNGLMLTYG------GMSFQPVTIPTSLYIFKNFTSAGFWVTELLKNNKELKT 334 Query: 350 KKFDLDQLITHVLPFKKISEGFELLNSG 377 + + E L G Sbjct: 335 STLNQIIAWYEEGKLTDA-KSIETLYDG 361 >1V3V-A nrPDB Length = 333 Score = 79.0 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 43/244 (17%), Positives = 86/244 (35%), Gaps = 23/244 (9%) Query: 153 MNTSTFTEYTVVDESSVAKI----DDAAPPEKV-CLIGCGFSTGYGAAVKTGKVKPGSTC 207 + S +T + + D + K+ D P IG T Y ++ VK G T Sbjct: 90 LAQSGWTTHFISDGKGLEKLLTEWPDKLPLSLALGTIGMPGLTAYFGLLEVCGVKGGETV 149 Query: 208 VVF-GLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVL 266 +V G VG V K G +++G + +K +G + K + E L Sbjct: 150 LVSAAAGAVGSVVGQIAKLKG-CKVVGAAGSDEKIAYLKQIGFDAAFNYKTVNS-LEEAL 207 Query: 267 SEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVG----------VPPSAKMLTYD 316 + + + F+ +G ++ + S ++G + G +PP + Sbjct: 208 KKASPDGYDCYFDNVGGE--FLNTVLSQMKDFGKIAICGAISVYNRMDQLPPGPSPESII 265 Query: 317 PMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNS 376 L G ++ + + L+ L K + +T F+ + F + + Sbjct: 266 YKQLRIEGFIVYRWQGDVREKA-LRDLMKWVLEGKIQYHEHVTKG--FENMPAAFIEMLN 322 Query: 377 GQSI 380 G ++ Sbjct: 323 GANL 326 >5GXF-A nrPDB Length = 330 Score = 77.0 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 45/264 (17%), Positives = 86/264 (32%), Gaps = 61/264 (23%) Query: 21 KCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIK--GTMVSKFPVIV 78 K +AAV + S+ ++ V EV + + + + D I G +V K+P + Sbjct: 15 KTQAAV-----KQLSLTDLPV-----GEVTVAVEYSTVNYKDGLCIGPGGGLVRKYPHVP 64 Query: 79 GHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADG 138 G + G VE+ KPGDKV+ Sbjct: 65 GIDFAGTVEN--SSDERYKPGDKVVLTGW------------------------------- 91 Query: 139 TTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGA--AV 196 + +++ V + + + + +G T A A+ Sbjct: 92 ----------RVGEAHWGGYSQKANVRADWLVPLPEGLDTRQAMAVGTAGFTAMLAVMAL 141 Query: 197 KTGKVKPGS-TCVVFG-LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 + + PG +V G GGVG G + + + + ++GAT+ ++ Sbjct: 142 EDHGLTPGHGPVLVTGAAGGVGSVATAILAHLG-YEVAAVTGRPETADYLTSLGATQIVA 200 Query: 255 PKDSTKPISEVL-SEMTGNNVGYT 277 + + + L SE+ V Sbjct: 201 RDEINETVKRPLESEIWAGCVDAV 224 >2Y05-A nrPDB Length = 328 Score = 74.7 bits (182), Expect = 6e-14, Method: Composition-based stats. Identities = 36/226 (15%), Positives = 70/226 (30%), Gaps = 17/226 (7%) Query: 166 ESSVAKIDDAAPPEKV-CLIGCGFSTGYGAAVKTGKVKPGSTCVV-FGLGGVGLSVIMGC 223 E + + D P +G T Y ++ VK G T +V G VG V Sbjct: 102 EKLLTEWPDTIPLSLALGTVGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIA 161 Query: 224 KSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGH 283 K G +++G + +K +G + K + E L + + + F+ +G Sbjct: 162 KLKG-CKVVGAVGSDEKVAYLQKLGFDVVFNYKTVES-LEETLKKASPDGYDCYFDNVGG 219 Query: 284 LETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVF---------GGL 334 + + +G + G + P + G Sbjct: 220 E--FSNTVIGQMKKFGRIAICGAISTYNRTGPLPPGPPPEIVIYQELRMEAFVVYRWQGD 277 Query: 335 KSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSI 380 + + L+ L K + I F+ + F + G ++ Sbjct: 278 ARQKALKDLLKWVLEGKIQYKEYIIEG--FENMPAAFMGMLKGDNL 321 >3WID-A nrPDB Length = 369 Score = 73.2 bits (178), Expect = 2e-13, Method: Composition-based stats. Identities = 62/382 (16%), Positives = 120/382 (31%), Gaps = 36/382 (9%) Query: 19 VIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFP--- 75 + A V K +I++ P+ E ++K + GIC TD + G + + Sbjct: 1 MSTINAIVTDAPKGGVKYTKIDMPEPEKYEAKLKPVYIGICGTDRGEVAGALSFTYNPEG 60 Query: 76 ---VIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGR 132 +++GHEA V + +K GD V+PL +C CR + C D Sbjct: 61 ENFLVLGHEALLQVLDV-SDNNYIKRGDFVVPLVRRP-GKCVNCRIGRQDNCSIGDPDKH 118 Query: 133 GVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKID-DAAPPEKVCLIGCGFSTG 191 G F V++ + KI P + V F Sbjct: 119 EAGITGLHGFMRDVIYDDI-------QNLVKVNDPDLGKIAVLTEPLKNVMKAFEVFDVV 171 Query: 192 YGAAVKTGKVKP--GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGA 249 ++ G VV G G K G + ++ + + K + Sbjct: 172 SKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFD-VTMVNRHDETENKMKMMD- 229 Query: 250 TECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPS 309 + + K + + + + G T+ + + N G ++ G Sbjct: 230 DFGVGFSNYLKDMPDKI--------DLLVDTSGDPSTIFKFVKKVN-NNGVVILFGFNGK 280 Query: 310 AKMLTYD----PMLLFTGRTWKGCV-FGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPF 364 A + ++ T G V + + L + + +IT+ Sbjct: 281 APGYPVNGEDIDYIVERNITIAGSVDAAKIHYVQALDSLSNWYHRHPQTIKDIITYEAKP 340 Query: 365 KKISEGFELLNSGQSIRTVLTF 386 ++ + F+ I+TV+ + Sbjct: 341 EETNIFFQ--KPKGEIKTVIKW 360 >1O89-A nrPDB Length = 345 Score = 71.6 bits (174), Expect = 5e-13, Method: Composition-based stats. Identities = 51/312 (16%), Positives = 96/312 (30%), Gaps = 62/312 (19%) Query: 46 TKEVRIKILATGICRTDDHVI--KGTMVSKFPVIVGHEATGIVESIGEGVTTVKPGDKVI 103 +V + + + + D I KG ++ FP+I G + G V + G +V+ Sbjct: 48 EGDVTVDVHWSSLNYKDALAITGKGKIIRNFPMIPGIDFAGTVRT--SEDPRFHAGQEVL 105 Query: 104 PLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTV 163 +TG GV + + E Sbjct: 106 -------------------------LTGWGVGEN----------------HWGGLAEQAR 124 Query: 164 VDESSVAKIDDAAPPEKVCLIGCGFSTGYGA--AVKTGKVKP--GSTCVVFGLGGVGLSV 219 V + + K +IG T A++ V+P G V GGVG + Sbjct: 125 VKGDWLVAMPQGLDARKAMIIGTAGFTAMLCVMALEDAGVRPQDGEIVVTGASGGVGSTA 184 Query: 220 IMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFE 279 + G +++ + + E ++GA+ + P+D + ++ + + Sbjct: 185 VALLHKLG-YQVVAVSGRESTHEYLKSLGASRVL-PRDEFAESRPLEKQVWAGAIDTVGD 242 Query: 280 VIGHLETMIDALASCHMNYGTSV-VVGVPPSAK-MLTYDPMLLFTGRT--WKGCVFGGLK 335 + A MNYG V G+ T P +L R + + Sbjct: 243 KVL-------AKVLAQMNYGGCVAACGLAGGFTLPTTVMPFILRNVRLQGVDSVMTPPER 295 Query: 336 SRDDVPKLVTEF 347 +LV + Sbjct: 296 RAQAWQRLVADL 307 >2J3K-A nrPDB Length = 345 Score = 63.6 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 45/270 (16%), Positives = 87/270 (32%), Gaps = 31/270 (11%) Query: 130 TGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEK-VCLIGCGF 188 +G G + + + T + + P L+G Sbjct: 89 SGHPDYKKGDLLWGIVAWEEYSVITPMTHAHFKIQHT--------DVPLSYYTGLLGMPG 140 Query: 189 STGYGAAVKTGKVKPGSTCVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAM-A 246 T Y + K G T V G VG V K G ++G +K+K + Sbjct: 141 MTAYAGFYEVCSPKEGETVYVSAASGAVGQLVGQLAKMMGCY-VVGSAGSKEKVDLLKTK 199 Query: 247 VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGV 306 G + + K+ + ++ L N + FE +G M+DA+ +G V G+ Sbjct: 200 FGFDDAFNYKEESD-LTAALKRCFPNGIDIYFENVGG--KMLDAVLVNMNMHGRIAVCGM 256 Query: 307 PPS-----AKMLTYDPMLLFTGRTWKGCVFGGLKSR-DDVPKLVTEFLAKKFDLDQLITH 360 + + +++ +G V + + V + + IT+ Sbjct: 257 ISQYNLENQEGVHNLSNIIYKRNRIQGFVVSDFYDKYSKFLEFVLPHIREGK-----ITY 311 Query: 361 VLP----FKKISEGFELLNSGQSI-RTVLT 385 V +K E L G+++ + V+ Sbjct: 312 VEDVADGLEKAPEALVGLFHGKNVGKQVVV 341 >2VNA-A nrPDB Length = 357 Score = 58.2 bits (139), Expect = 7e-09, Method: Composition-based stats. Identities = 64/381 (16%), Positives = 118/381 (30%), Gaps = 85/381 (22%) Query: 32 QPFSIEEIEVAP-PKTKEVRIKILATGI-----C------RTDDHVIKGTMVSKFPVIVG 79 + F +EE+ + +V+++ L + C TD ++ + V+ G Sbjct: 22 ENFRMEEVYLPDNINEGQVQVRTLYLSVDPYMRCRMNEDTGTD-YITPWQLSQ---VVDG 77 Query: 80 HEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITGRGVLADGT 139 GI+E T + GD V + P + V+ DG Sbjct: 78 G-GIGIIEE--SKHTNLTKGDFVTSFYWPWQTK---------------------VILDGN 113 Query: 140 TRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTG 199 + + V ++ Y + IG T + G Sbjct: 114 SLEKVDPQLVDGHLS------YFL------------------GAIGMPGLTSLIGIQEKG 149 Query: 200 KVKPGS--TCVVFGL-GGVGLSVIMGCKSAGASRIIGI-DLNKDKFEKAMAVGATECISP 255 + GS T VV G G G G SR++GI ++ +G I+ Sbjct: 150 HITAGSNKTMVVSGAAGACGSVAGQIGHFLGCSRVVGICGTHEKCILLTSELGFDAAINY 209 Query: 256 KDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVG-------VPP 308 K ++E L E V F+ +G + D + S ++ G P Sbjct: 210 K--KDNVAEQLRESCPAGVDVYFDNVGG--NISDTVISQMNENSHIILCGQISQYNKDVP 265 Query: 309 SAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDV----PKLVTEFLAKKFDLDQLITHVLPF 364 L+ + R F L +D +L F K + + + + Sbjct: 266 YPPPLSPAIEAIQKERNITRERFLVLNYKDKFEPGILQLSQWFKEGKLKIKETVING--L 323 Query: 365 KKISEGFELLNSGQSIRTVLT 385 + + F+ + +G +I + Sbjct: 324 ENMGAAFQSMMTGGNIGKQIV 344 >2ZB3-A nrPDB Length = 353 Score = 54.3 bits (129), Expect = 9e-08, Method: Composition-based stats. Identities = 40/212 (18%), Positives = 68/212 (32%), Gaps = 21/212 (9%) Query: 181 VCLIGCGFSTGYGAAVKTGKVKPGS--TCVVFGL-GGVGLSVIMGCKSAGASRIIGI-DL 236 + IG T + G + GS T VV G G G G SR++GI Sbjct: 132 LGAIGMPGLTSLIGVQEKGHISAGSNQTMVVSGAAGACGSLAGQIGHLLGCSRVVGICGT 191 Query: 237 NKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHM 296 + +G ++ K ++E L E V F+ +G + +A+ S Sbjct: 192 QEKCLFLTSELGFDAAVNYKTGN--VAEQLREACPGGVDVYFDNVGG--DISNAVISQMN 247 Query: 297 NYGTSVVVG-------VPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDV----PKLVT 345 ++ G P L + R F L +D +L Sbjct: 248 ENSHIILCGQISQYSNDVPYPPPLPPAVEAIRKERNITRERFTVLNYKDKFEPGILQLSQ 307 Query: 346 EFLAKKFDLDQLITHVLPFKKISEGFELLNSG 377 F K + + T + + F+ + +G Sbjct: 308 WFKEGKLKVKE--TMAKGLENMGVAFQSMMTG 337 >1ZCJ-A nrPDB Length = 463 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 189 STGYGAAVKTGKVKPGSTCVVFGLGGVG-LSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 247 ST GA+ KT +P S+ V GLG +G I + ++ ++ + + + A + Sbjct: 22 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 79 >3ZWA-A nrPDB Length = 742 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 28/60 (46%), Gaps = 3/60 (5%) Query: 189 STGYGAAVKTGKVKPGSTCVVFGLGGVG-LSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 247 ST GA+ KT +P S+ V GLG +G I + ++ ++ + + + A + Sbjct: 301 STPSGASWKTASAQPVSSVGVLGLGTMGRGIAISFARV--GISVVAVESDPKQLDAAKKI 358 >2EGU-A nrPDB Length = 308 Score = 41.2 bits (95), Expect = 8e-04, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 33/64 (51%), Gaps = 2/64 (3%) Query: 194 AAVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 AA K GK+KPG T V G G+GL+++ K A ++ ++ ++ A GA Sbjct: 55 AAEKAGKLKPGDTIVEPTSGNTGIGLAMVAAAKGYKAVLVMPDTMSLERRNLLRAYGAEL 114 Query: 252 CISP 255 ++P Sbjct: 115 VLTP 118 >1X14-A nrPDB Length = 401 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 38/110 (34%), Gaps = 2/110 (1%) Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 + + P + +V G G GL+ I S GA + D + E+ ++GA Sbjct: 160 FTGQITAAGKVPPAKVMVIGAGVAGLAAIGAANSLGA-IVRAFDTRPEVKEQVQSMGAEF 218 Query: 252 C-ISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGT 300 + K+ M+ + E+ +D + + + G Sbjct: 219 LELDFKEEAGSGDGYAKVMSDAFIKAEMELFAAQAKEVDIIVTTALIPGK 268 >4DIO-A nrPDB Length = 405 Score = 39.7 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 40/109 (36%), Gaps = 9/109 (8%) Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS 254 + P + V G G GL I + GA + D+ E+ ++GA I+ Sbjct: 181 MMTAAGTVPAAKIFVMGAGVAGLQAIATARRLGA-VVSATDVRPAAKEQVASLGAK-FIA 238 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVV 303 +D +E G Y E+ G + AL + H+ V+ Sbjct: 239 VEDEEFKAAE----TAGG---YAKEMSGEYQVKQAALVAEHIAKQDIVI 280 >6BII-A nrPDB Length = 333 Score = 37.7 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 30/80 (37%), Gaps = 10/80 (12%) Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 + + G G T + G G +G ++ K G RI+ + K E +GA Sbjct: 137 AWHPKMFLGYDVYGKTIGIVGFGRIGQAIAKRAKGFGM-RILYTARS-RKPEAEKELGAE 194 Query: 251 ECISPKDSTKPISEVLSEMT 270 KP+ E+L E Sbjct: 195 F--------KPLEELLRESD 206 >3MGG-A nrPDB Length = 276 Score = 37.7 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 23/108 (21%), Positives = 43/108 (39%), Gaps = 9/108 (8%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 PG+ + G G +G ++ K+ + I ID++ + EKA TE K+ Sbjct: 37 PGAKVLEAGCG-IGAQTVILAKNNPDAEITSIDISPESLEKAREN--TEKNGIKNVKFLQ 93 Query: 263 SEVLSEMTGNN------VGYTFEVIGHLETMIDALASCHMNYGTSVVV 304 + + S ++ V + E + E + +L GT V+ Sbjct: 94 ANIFSLPFEDSSFDHIFVCFVLEHLQSPEEALKSLKKVLKPGGTITVI 141 >1BW9-B nrPDB Length = 356 Score = 37.7 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 17/49 (34%), Positives = 27/49 (55%), Gaps = 1/49 (2%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 G T +V GLG VG S+ AGA +++ D + ++ A+A+G T Sbjct: 176 GLTVLVQGLGAVGGSLASLAAEAGA-QLLVADTDTERVAHAVALGHTAV 223 >2VHY-A nrPDB Length = 377 Score = 37.4 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 18/80 (22%), Positives = 25/80 (31%), Gaps = 12/80 (15%) Query: 172 IDDAAPPEKVCLIGCGFSTGYGAAVKTGK----------VKPGSTCVVFGLGGVGLSVIM 221 + AP +V Y G V+P VV G G G + Sbjct: 127 LPLLAPMSEVAGRLAAQVGAYHLMRTQGGRGVLMGGVPGVEPAD-VVVIGAGTAGYNAAR 185 Query: 222 GCKSAGASRIIGIDLNKDKF 241 GA + +D+N DK Sbjct: 186 IANGMGA-TVTVLDINIDKL 204 >1XLT-A nrPDB Length = 384 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 + + P + +VFG+G GL I K GA ++ D+ E+ ++G Sbjct: 159 AFPMMMTAAGTVPPARVLVFGVGVAGLQAIATAKRLGA-VVMATDVRAATKEQVESLG 215 >3VPX-A nrPDB Length = 364 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 26/51 (50%), Gaps = 2/51 (3%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKA-MAVGATEC 252 G T V G+G V ++ GA ++I D+N++ ++A A GAT Sbjct: 172 AGKTVAVQGVGNVAYALCEYLHEEGA-KLIITDINEEAVQRAVDAFGATAV 221 >4XIJ-A nrPDB Length = 275 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 22/59 (37%), Gaps = 4/59 (6%) Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK----FEKAMAVGA 249 V G + +V G GG + ++ G RI + ++ K + A GA Sbjct: 117 GVTGALGTAGDSALVIGSGGTAPAAVVALAELGVQRITIVARDEGKASRLVDLARRCGA 175 >6C55-A nrPDB Length = 340 Score = 36.6 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 28/164 (17%), Positives = 48/164 (29%), Gaps = 22/164 (13%) Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK-FEKAMA 246 +T Y G V G G G + K G +IG + + F+KA Sbjct: 1 MTTVYYDQDVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIG--IRPGRSFDKAKE 58 Query: 247 VGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHL-----ETMIDALASCHMNYGTS 301 G P++E + + V E+ G + E ++ + +G + Sbjct: 59 DGFDVF--------PVAEAVKQADVIMVLLPDEIQGDVYKNEIEPNLEKHNALAFAHGFN 110 Query: 302 VVVGVPPSAKMLTYD------PMLLFTGRTWKGCVFGGLKSRDD 339 + GV + P L +G L Sbjct: 111 IHFGVIQPPADVDVFLVAPKGPGHLVRRTFVEGSAVPSLFGIQQ 154 >3X2F-A nrPDB Length = 411 Score = 36.2 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 39/121 (32%), Gaps = 14/121 (11%) Query: 185 GCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKA 244 G G ST T + G VV G G G + + GA R+I +++ K +A Sbjct: 178 GTGQSTWDAIMRNTNLLVAGKNVVVAGYGWCGRGIALRAAGLGA-RVIVTEVDPVKAVEA 236 Query: 245 MAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVV 304 + G T P+ E + + G+ + + + Sbjct: 237 IMDGFTVM--------PMKEAVKI-----ADFVITASGNTDVLSKEDILSLKDGAVLANA 283 Query: 305 G 305 G Sbjct: 284 G 284 >5Z1Z-A nrPDB Length = 329 Score = 36.2 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 14/55 (25%), Positives = 23/55 (41%), Gaps = 3/55 (5%) Query: 198 TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 TG G T V G G +G++++ K G R++ D A+ +G Sbjct: 138 TGFTMYGKTAGVIGTGKIGVAMLRILKGFGM-RLLAFDPYPS--AAALELGVEYV 189 >1CYD-A nrPDB Length = 244 Score = 35.8 bits (81), Expect = 0.033, Method: Composition-based stats. Identities = 26/165 (15%), Positives = 49/165 (29%), Gaps = 37/165 (22%) Query: 204 GSTCVVFGLG-GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 G +V G G G+G + ++GA + N D A Sbjct: 7 GLRALVTGAGKGIGRDTVKALHASGAKVVAVTRTNSDLVSLAKEC--------------- 51 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFT 322 + +G + AL G V + +A ++ P L T Sbjct: 52 ---------PGIEPVCVDLGDWDATEKAL------GGIGPVDLLVNNAALVIMQPFLEVT 96 Query: 323 GRTWKGCVFGGLKSRDDVPKLVTEFLAKK------FDLDQLITHV 361 + L+S V ++V + + ++ ++ HV Sbjct: 97 KEAFDRSFSVNLRSVFQVSQMVARDMINRGVPGSIVNVSSMVAHV 141 >2B25-A nrPDB Length = 336 Score = 35.8 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 42/127 (33%), Gaps = 16/127 (12%) Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGA-SRIIGIDLNKDKFEKAMAVGATECISPKDS 258 + PG T + G G G + K+ G+ R+I ++ KD + A + K Sbjct: 102 DINPGDTVLEAGSGS-GGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK-------NYKHW 153 Query: 259 TKPISEVLSEMTGNNVGYTF-EVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDP 317 E +NV + ++ G E + + + P + + P Sbjct: 154 RDSWKLSHVEEWPDNVDFIHKDISGATEDIKSLTFDA------VALDMLNPHVTLPVFYP 207 Query: 318 MLLFTGR 324 L G Sbjct: 208 HLKHGGV 214 >5EKU-A nrPDB Length = 390 Score = 35.0 bits (79), Expect = 0.050, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 V P + + G G GL +M K GA ++ ++ +++ + A Sbjct: 92 HVTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE 136 >4M36-A nrPDB Length = 343 Score = 35.0 bits (79), Expect = 0.050, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 V P + + G G GL +M K GA ++ ++ +++ + A Sbjct: 57 HVTPETGVLEIGAGS-GLLSLMAAK-LGAKWVVAVEGSEELAKLARE 101 >4GCM-A nrPDB Length = 312 Score = 35.0 bits (79), Expect = 0.052, Method: Composition-based stats. Identities = 33/224 (14%), Positives = 54/224 (24%), Gaps = 57/224 (25%) Query: 207 CVVFGLGGVGLSVIMGCKSA--------------------------GASRIIGIDLNKDK 240 + G G G++ + A G I G DL+ Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTVMIERGIPGGQMANTEEVENFPGFEMITGPDLSTKM 68 Query: 241 FEKAMAVGATE---------------CISPKDSTKPISEVLSEMTGN----NVGYTFEVI 281 FE A GA I+ + V+ V E+ Sbjct: 69 FEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQELG 128 Query: 282 GHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVP 341 G + V+G SA T + Sbjct: 129 GRGVSYCAVCDGAFFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIV-----HRRDELRAQ 183 Query: 342 KLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQSIRTVLT 385 +++ + K +D + +H L I+E G+ LT Sbjct: 184 RILQDRAFKNDKIDFIWSHTLK--SINE-----KDGKVGSVTLT 220 >1VH3-A nrPDB Length = 262 Score = 35.0 bits (79), Expect = 0.056, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 33/83 (39%), Gaps = 3/83 (3%) Query: 190 TGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGA 249 T A PG + V +GASR+I N++ + A + GA Sbjct: 4 TVIIPARFASSRLPGKPLADIKGKPMIQHVFEKALQSGASRVIIATDNENVADVAKSFGA 63 Query: 250 TEC---ISPKDSTKPISEVLSEM 269 C ++ T+ ++EV+ ++ Sbjct: 64 EVCMTSVNHNSGTERLAEVVEKL 86 >1V9L-A nrPDB Length = 421 Score = 35.0 bits (79), Expect = 0.060, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 35/85 (41%), Gaps = 7/85 (8%) Query: 160 EYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAV-------KTGKVKPGSTCVVFGL 212 EY+ + +V + + PPE ++TG+G AV K G T + G+ Sbjct: 159 EYSKIKGYNVPGVFTSKPPELWGNPVREYATGFGVAVATREMAKKLWGGIEGKTVAIQGM 218 Query: 213 GGVGLSVIMGCKSAGASRIIGIDLN 237 G VG + GA I D+N Sbjct: 219 GNVGRWTAYWLEKMGAKVIAVSDIN 243 >3KYD-B nrPDB Length = 551 Score = 35.0 bits (79), Expect = 0.061, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 20/45 (44%) Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLN 237 G + + G +V G GG+G ++ G S I IDL+ Sbjct: 8 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 52 >3KYC-B nrPDB Length = 660 Score = 35.0 bits (79), Expect = 0.061, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 20/45 (44%) Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLN 237 G + + G +V G GG+G ++ G S I IDL+ Sbjct: 26 GLPRELAEAVAGGRVLVVGAGGIGCELLKNLVLTGFSHIDLIDLD 70 >1I9G-A nrPDB Length = 280 Score = 34.7 bits (78), Expect = 0.069, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 45/111 (40%), Gaps = 4/111 (3%) Query: 196 VKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAG-ASRIIGIDLNKDKFEKAMAVGATECIS 254 V G + PG+ + G G G + ++ G A ++I + D E A + Sbjct: 92 VHEGDIFPGARVLEAGAGS-GALTLSLLRAVGPAGQVISYEQRADHAEHARRNVSGCYGQ 150 Query: 255 PKDSTKPISEVLS--EMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVV 303 P D+ + + L+ E+ +V + ++DA++ + G +V Sbjct: 151 PPDNWRLVVSDLADSELPDGSVDRAVLDMLAPWEVLDAVSRLLVAGGVLMV 201 >5F8E-A nrPDB Length = 377 Score = 34.3 bits (77), Expect = 0.084, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 48/116 (41%), Gaps = 6/116 (5%) Query: 200 KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI-SPKDS 258 +++ G+ FG G G +V + ++ GASR GID + + A + + Sbjct: 184 RLRSGADVADFGCGS-GRAVKLMAQAFGASRFTGIDFSDEAVAAGTEEAARLGLANATFE 242 Query: 259 TKPISEVLSEMTGNNVGYTFEVI---GHLETMIDALASCHMNYGTSVVVGVPPSAK 311 ++E L ++ +V F+ I ++ + G ++V + S++ Sbjct: 243 RHDLAE-LDKVGAYDVITVFDAIHDQAQPARVLQNIYRALRPGGVLLMVDIKASSQ 297 >5ILO-A nrPDB Length = 271 Score = 34.3 bits (77), Expect = 0.085, Method: Composition-based stats. Identities = 24/105 (22%), Positives = 40/105 (38%), Gaps = 11/105 (10%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC---------ISPKD 257 V G GG+GL V +AGA+++ IDL + E A ++ K Sbjct: 19 VVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANKK 78 Query: 258 STKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSV 302 + E +++ GN + V G D + +N G + Sbjct: 79 GVEATYEEIAKTFGN-IDIVVNVAGIFND-KDVQRTLLVNLGGII 121 >2O23-A nrPDB Length = 265 Score = 34.3 bits (77), Expect = 0.097, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 28/88 (31%), Gaps = 4/88 (4%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD--STKPISE 264 + G G+GL+ GAS ++ N +A +G +P D S K + Sbjct: 16 VITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDVQT 75 Query: 265 VLSEMTG--NNVGYTFEVIGHLETMIDA 290 L+ G V G Sbjct: 76 ALALAKGKFGRVDVAVNCAGIAVASKTY 103 >4N7R-A nrPDB Length = 472 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 29/69 (42%), Gaps = 6/69 (8%) Query: 184 IGCGFSTGYGAAVKTGKVKPGST------CVVFGLGGVGLSVIMGCKSAGASRIIGIDLN 237 I G + AAV+ +K + V G G +G VI + G ++++ ++ + Sbjct: 181 IASGAVSVSSAAVELALMKLPQSSNVSARMCVIGAGKMGKLVIKHLMAKGCTKVVVVNRS 240 Query: 238 KDKFEKAMA 246 +++ Sbjct: 241 EERVSAIRE 249 >5JXW-A nrPDB Length = 498 Score = 33.9 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 33/176 (18%), Positives = 52/176 (29%), Gaps = 42/176 (23%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 G VV G G VG G GA R+I ++ PI Sbjct: 270 AGKKIVVLGYGEVGKGCAQGLSGVGA-RVIVTEI-----------------------DPI 305 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFT 322 + + M G V +V+ + I A + ++T + M Sbjct: 306 CALQASMEGYQVSVLEDVVSEADIFITATG----------------NKDVITVEHMRKMK 349 Query: 323 GRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGFELLNSGQ 378 + + G DV L K ++ Q + H F + LL G+ Sbjct: 350 ENAYIANI-GHFDDEIDVYGLENYPGIKVIEVKQNV-HKFTFPDTQKSVILLCKGR 403 >4K2X-A nrPDB Length = 523 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 11/44 (25%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 V+ G G GL + + AGA R + ++ + + + A+G Sbjct: 25 VVIAGAGPTGLMLACELRLAGA-RTLVLERLAEPVDFSKALGVH 67 >5AOV-A nrPDB Length = 336 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 27/80 (33%), Gaps = 10/80 (12%) Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 + G G T + G G +G ++ K G + I K + +GA Sbjct: 137 AWHPKWFLGYELYGKTIGIVGFGRIGQAIARRAK--GFNMRILYYSRTRKSQAEKELGAE 194 Query: 251 ECISPKDSTKPISEVLSEMT 270 +P+ EVL E Sbjct: 195 Y--------RPLEEVLKESD 206 >4CUK-A nrPDB Length = 338 Score = 33.9 bits (76), Expect = 0.12, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 G T V G G +G++ + K G R++ D A+ +G Sbjct: 144 GKTAGVIGTGKIGVAALRILKGFGM-RLLAFDPYPS--TAALDLGVEYV 189 >1DXY-A nrPDB Length = 333 Score = 33.5 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 16/39 (41%), Gaps = 1/39 (2%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEK 243 T V G G +G I K GA ++I D K + Sbjct: 146 QTVGVMGTGHIGQVAIKLFKGFGA-KVIAYDPYPMKGDH 183 >6ACF-A nrPDB Length = 367 Score = 33.5 bits (75), Expect = 0.15, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 28/72 (38%), Gaps = 3/72 (4%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKA-MAVGATECISPKDSTKPI 262 G V G+G V + GA ++I D+NK+ +A GA + P D Sbjct: 173 GKVVAVQGVGNVAYHLCRHLHEEGA-KLIVTDINKEAVARAVEEFGAK-AVDPNDIYGVE 230 Query: 263 SEVLSEMTGNNV 274 ++ + + Sbjct: 231 CDIFAPCALGGI 242 >5UYY-A nrPDB Length = 381 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 23/49 (46%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI 253 V+ G G +G S+ + K I G D+ +++ E+A + + I Sbjct: 18 KKVVLIGTGLIGGSLALAIKKDHDVTITGYDIFQEQVERAKELHVVDEI 66 >3D3W-A nrPDB Length = 244 Score = 33.1 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 9/41 (21%), Positives = 18/41 (43%), Gaps = 2/41 (4%) Query: 203 PGSTCVVFGLG-GVGLSVIMGCKSAGASRIIGIDLNKDKFE 242 G +V G G G+G + + GA R++ + + + Sbjct: 6 AGRRVLVTGAGKGIGRGTVQALHATGA-RVVAVSRTQADLD 45 >3G1U-A nrPDB Length = 437 Score = 33.1 bits (74), Expect = 0.20, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%), Gaps = 1/36 (2%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNK 238 G TC V G G VG ++ GA R++ +++ Sbjct: 211 AGKTCCVCGYGDVGKGCAAALRAFGA-RVVVTEVDP 245 >4K28-A nrPDB Length = 269 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 22/49 (44%) Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK 240 GAA K G G +V G GGVG ++ AG + I D + + Sbjct: 113 LGAAHKHGFEPAGKRALVIGCGGVGSAIAYALAEAGIASITLCDPSTAR 161 >1JWB-B nrPDB Length = 249 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 17/33 (51%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLN 237 S ++ GLGG+G + SAG + +D + Sbjct: 32 SRVLIVGLGGLGCAASQYLASAGVGNLTLLDFD 64 >1XDW-A nrPDB Length = 331 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 16/36 (44%), Gaps = 1/36 (2%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK 240 T V GLG +G GA +IG D+ + K Sbjct: 147 CTVGVVGLGRIGRVAAQIFHGMGA-TVIGEDVFEIK 181 >5JJC-A nrPDB Length = 342 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 28/61 (45%), Gaps = 4/61 (6%) Query: 195 AVKTGKVKPGSTCVVFG-LGGVGLSVIMGCKSAGASRIIGI--DLNKDKFEKAMAVGATE 251 A K G ++PG +V G G G+ + M K+ G I I +++K + +GA Sbjct: 53 AEKRGLLRPGG-VIVEGTAGNTGIGLTMVAKALGYRTAIVIPETASQEKKDALRLLGAEL 111 Query: 252 C 252 Sbjct: 112 I 112 >1ZFN-A nrPDB Length = 253 Score = 33.1 bits (74), Expect = 0.22, Method: Composition-based stats. Identities = 9/38 (23%), Positives = 16/38 (42%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFE 242 S ++ GLGG+G + AG ++ D + Sbjct: 31 SQVLIIGLGGLGTPAALYLAGAGVGTLVLADDDDVHLS 68 >1NVM-B nrPDB Length = 312 Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 41/120 (34%), Gaps = 11/120 (9%) Query: 206 TCVVFGLGGVG--LS--VIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKP 261 + G G +G L V+ K ++GID D +A +G T + Sbjct: 6 KVAIIGSGNIGTDLMIKVLRNAKYLEMGAMVGIDAASDGLARAQRMGVTTTYA------G 59 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLF 321 + ++ ++ + F+ + + G ++ + P+A P++ Sbjct: 60 VEGLIKLPEFADIDFVFDATSASAHVQNEALLRQAKPG-IRLIDLTPAAIGPYCVPVVNL 118 >2EKL-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 G T + G G +G V + + G +++ D+ + EKA + A Sbjct: 141 AGKTIGIVGFGRIGTKVGIIANAMGM-KVLAYDILDIR-EKAEKINAKAV 188 >4WO8-A nrPDB Length = 716 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 17/98 (17%), Positives = 31/98 (31%), Gaps = 4/98 (4%) Query: 117 RNPDGNLCIRSDITGRGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAA 176 C+ ++ G L + F + +Y V + + + Sbjct: 42 LGGTLAQCVNTNAYNPGALLPRSCDLNAYETFRDFF--DAVIADYHKVPDGKIQH-PKSN 98 Query: 177 PPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGG 214 + L +T YG V + +V+ G T FG G Sbjct: 99 FGDLKSLSFTDLNT-YGNLVVSTRVRLGRTVEGFGFGP 135 >4YRY-B nrPDB Length = 468 Score = 32.3 bits (72), Expect = 0.33, Method: Composition-based stats. Identities = 14/125 (11%), Positives = 34/125 (27%), Gaps = 10/125 (8%) Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTK 260 ++ G V G G + GA ++ + ++ A ++ Sbjct: 276 IRVGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARR---------EEYHH 326 Query: 261 PISEVLSEMTGNNVGYTF-EVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 + E + + + G++E M G+ VP + + Sbjct: 327 ALEEGIEFLWLTLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDM 386 Query: 320 LFTGR 324 + Sbjct: 387 VIEAI 391 >5JE5-A nrPDB Length = 247 Score = 32.3 bits (72), Expect = 0.34, Method: Composition-based stats. Identities = 17/118 (14%), Positives = 39/118 (33%), Gaps = 21/118 (17%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G + + G G + GA++++G+D+++ E A + P+ Sbjct: 42 GKSVLDLACG-FGFFGREIYR-RGAAKVVGVDISEKMIELARE-------ESRKYGDPLE 92 Query: 264 EVLSEMTGNNVGYTFEVIG------------HLETMIDALASCHMNYGTSVVVGVPPS 309 + ++ F+++ +L M + + G V V P Sbjct: 93 FHVRDVANMEPLGQFDLVNAAWLFNYADSVENLRKMFKVVRASLKPDGKLVAYTVDPD 150 >2HAE-A nrPDB Length = 386 Score = 32.3 bits (72), Expect = 0.35, Method: Composition-based stats. Identities = 28/189 (14%), Positives = 55/189 (29%), Gaps = 38/189 (20%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDL------------------------NKDK- 240 VV G+G G +++ G ++ +D N ++ Sbjct: 184 KVVVNGIGAAGYNIVKFLLDLGVKNVVAVDRKGILNENDPETCLNEYHLEIARITNPERL 243 Query: 241 ---FEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMN 297 E A+ GA I E + +M+ V + + + Sbjct: 244 SGDLETALE-GADFFIGVSRGNILKPEWIKKMSRKPVIFAL------ANPVPEIDPELAR 296 Query: 298 YGTSVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQ- 356 + +V S + +L F G KG V K ++ E +A+ + + Sbjct: 297 EAGAFIVATGRSDHPNQVNNLLAFPGI-MKGAVEKRSKITKNMLLSAVEAIARSCEPEPE 355 Query: 357 -LITHVLPF 364 +I Sbjct: 356 RIIPEAFDM 364 >5U9P-A nrPDB Length = 265 Score = 32.3 bits (72), Expect = 0.36, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 31/88 (35%), Gaps = 10/88 (11%) Query: 204 GSTCVVFGLG-GVGLSVIMGCKSAGASRIIGIDLNKDKFE-KAMA-----VGATECISPK 256 G ++ G G G+GL++ G AGA+ +I D N++K A A + Sbjct: 20 GRRALITGSGRGIGLTLARGLAEAGAAIVIN-DRNEEKAATLARRFRDEGFAADHAVFDV 78 Query: 257 DSTKPISEVLSEMTG--NNVGYTFEVIG 282 + + E + G Sbjct: 79 AEHAQVRAAIDEFEARVGAIDILVNNAG 106 >6APH-A nrPDB Length = 445 Score = 32.3 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 21/58 (36%), Gaps = 3/58 (5%) Query: 191 GYGAAVKTGKVK-PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK-FEKAMA 246 A + V G VV G G VG + AG S + +++ + AM Sbjct: 212 AVDAIRRATDVMLAGKRVVVCGFGDVGKGTAASFRGAG-SIVTVTEIDPICALQAAME 268 >4XGI-A nrPDB Length = 436 Score = 32.3 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 19/48 (39%) Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGID 235 F G AA K G G+ V G G VG + AGA I D Sbjct: 215 FVVGCEAAKKKGVEIEGARIAVQGFGNVGGIAAKLFQEAGAKVIAVQD 262 >3GDH-A nrPDB Length = 241 Score = 32.3 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 16/39 (41%), Gaps = 2/39 (5%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAM 245 VV GVG + I R+I ID++ K A Sbjct: 81 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 117 >3EGI-A nrPDB Length = 206 Score = 32.3 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 16/39 (41%), Gaps = 2/39 (5%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAM 245 VV GVG + I R+I ID++ K A Sbjct: 46 VVVDAFCGVGGNTIQFA--LTGMRVIAIDIDPVKIALAR 82 >4INE-A nrPDB Length = 454 Score = 32.3 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 22/50 (44%), Gaps = 2/50 (4%) Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 + G KPG T + G+G +G G + GIDL+ + A+ Sbjct: 235 RFGDFKPGQTMLDIGVG-IGGGARQVADEFGV-HVHGIDLSSNMLAIALE 282 >2HMT-A nrPDB Length = 144 Score = 32.3 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPI 262 V GLG G S++ G ++ +D+N++K + AT + + + + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEENELL 64 Query: 263 S 263 S Sbjct: 65 S 65 >1E3W-A nrPDB Length = 261 Score = 32.3 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 29/88 (32%), Gaps = 4/88 (4%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKD--STKPISE 264 + G G+GLS GA+ ++ N + +A +G +P + S K + Sbjct: 14 VITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEVQA 73 Query: 265 VLSEM--TGNNVGYTFEVIGHLETMIDA 290 L+ + G + Sbjct: 74 ALTLAKEKFGRIDVAVNCAGIAVAIKTY 101 >1V8B-A nrPDB Length = 479 Score = 32.0 bits (71), Expect = 0.42, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 31/102 (30%), Gaps = 14/102 (13%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G V+ G G VG K GA R+ +++ +A+ G Sbjct: 257 GKIVVICGYGDVGKGCASSMKGLGA-RVYITEIDPICAIQAVMEGFNVV----------- 304 Query: 264 EVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVG 305 L E+ + G+++ + N +G Sbjct: 305 -TLDEIVDKG-DFFITCTGNVDVIKLEHLLKMKNNAVVGNIG 344 >5BUT-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPI 262 V GLG G S++ G ++ +D+N++K + AT + + + + + Sbjct: 7 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEENELL 64 Query: 263 S 263 S Sbjct: 65 S 65 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 27/61 (44%), Gaps = 4/61 (6%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPI 262 V GLG G S++ G ++ +D+N++K + AT + + + + + Sbjct: 149 KQFAVIGLGRFGGSIVKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEENELL 206 Query: 263 S 263 S Sbjct: 207 S 207 >4FS8-A nrPDB Length = 383 Score = 32.0 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 29/134 (21%), Positives = 48/134 (35%), Gaps = 13/134 (9%) Query: 116 CRNPDGNLCIRSDITGRGV-LADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDD 174 C + C +S G + D + K + TS V ES + D Sbjct: 5 CASG----CQKSKNGGSTPSIRDHVADYYGKTLQSSADLKTSACKLAAAVPESHRKILAD 60 Query: 175 AAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGA-SRIIG 233 A GCG + +++ G+T + G G G V + K G ++IG Sbjct: 61 IADEVLEKFYGCGSTLPADGSLE------GATVLDLGCGT-GRDVYLASKLVGEHGKVIG 113 Query: 234 IDLNKDKFEKAMAV 247 +D+ ++ E A Sbjct: 114 VDMLDNQLEVARKY 127 >2YVG-A nrPDB Length = 408 Score = 32.0 bits (71), Expect = 0.44, Method: Composition-based stats. Identities = 24/141 (17%), Positives = 48/141 (34%), Gaps = 17/141 (12%) Query: 173 DDAAPPEKVCLIGCGFSTGYGAAVK-TGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRI 231 A P + + A + ++P S ++ G G +GL + ++AG + Sbjct: 113 PRALPTLQGATMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTAGV-HV 171 Query: 232 IGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFE--VIGHLETMID 289 ++ +A +P ++ + V FE V G ++ ++ Sbjct: 172 SLVETQPRLMSRA---------APATLADFVARYHAAQ---GVDLRFERSVTGSVDGVV- 218 Query: 290 ALASCHMNYGTSVVVGVPPSA 310 L VVVG+ A Sbjct: 219 LLDDGTRIAADMVVVGIGVLA 239 >2WWR-A nrPDB Length = 330 Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 30/79 (37%), Gaps = 1/79 (1%) Query: 178 PEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLN 237 PE + + G T + G ST + GLG +G ++ K G R + Sbjct: 129 PEAIEEVKNGGWTSWKPLWLCGYGLTQSTVGIIGLGRIGQAIARRLKPFGVQRFLYTGRQ 188 Query: 238 KDKFEKAMAVGATECISPK 256 + E+A A +P+ Sbjct: 189 P-RPEEAAEFQAEFVSTPE 206 >2ISQ-A nrPDB Length = 320 Score = 32.0 bits (71), Expect = 0.53, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 30/85 (35%), Gaps = 4/85 (4%) Query: 195 AVKTGKVKPGSTCVV---FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 A K G +KPG + ++ G GVGL+ K + ++ ++ +A G Sbjct: 55 AEKKGLIKPGESVLIEPTSGNTGVGLAFTAAAKGYKLIITMPASMSTERRIILLAFGVEL 114 Query: 252 CI-SPKDSTKPISEVLSEMTGNNVG 275 + P K E+ Sbjct: 115 VLTDPAKGMKGAIAKAEEILAKTPN 139 >4COO-A nrPDB Length = 563 Score = 31.6 bits (70), Expect = 0.54, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 195 AVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 A + G +KPG T + G G+GL++ + ++ ++ +K + A+GA Sbjct: 152 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 211 Query: 253 ISPKDS 258 +P ++ Sbjct: 212 RTPTNA 217 >3X43-A nrPDB Length = 332 Score = 31.6 bits (70), Expect = 0.55, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 5/70 (7%) Query: 187 GFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGI---DLNKDKFEK 243 S A K G +KPG T V G VG+++ M + G R + + + ++ + Sbjct: 47 ALSVVLDAEAK-GLLKPGDTIVECTSGNVGIALAMVAAARG-YRFVAVMGDTYSVERRKL 104 Query: 244 AMAVGATECI 253 A G + Sbjct: 105 IRAYGGKLVL 114 >1W1U-A nrPDB Length = 557 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 33/97 (34%), Gaps = 7/97 (7%) Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECIS-- 254 G G + GLGG+G + + AGA + I+ + + + + T + Sbjct: 160 HYGGSLKGKWVLTAGLGGMGGAQPLAATLAGACS-LNIESQQSRIDFRLE---TRYVDEQ 215 Query: 255 PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDAL 291 D + + + + G+ ++ L Sbjct: 216 ATDLDDALVRIAKYTA-EGKAISIALHGNAAEILPEL 251 >1M54-A nrPDB Length = 363 Score = 31.6 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 195 AVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 A + G +KPG T + G G+GL++ + ++ ++ +K + A+GA Sbjct: 87 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 146 Query: 253 ISPKDS 258 +P ++ Sbjct: 147 RTPTNA 152 >3JTJ-A nrPDB Length = 253 Score = 31.6 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 19/123 (15%), Positives = 41/123 (33%), Gaps = 8/123 (6%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI---SPKDST 259 PG + + V+ ++GA R+I + D + A G C+ + T Sbjct: 20 PGKPLADIAGKPMVVHVMERALASGADRVIVATDHPDVVKAVEAAGGEVCLTRADHQSGT 79 Query: 260 KPISEVLSEMTGNNVGYTFEVIGH-----LETMIDALASCHMNYGTSVVVGVPPSAKMLT 314 + ++EV+ + V G + + + VP ++ Sbjct: 80 ERLAEVIEHYGFADDDIIVNVQGDEPLVPPVIIRQVADNLAACSAGMATLAVPIASSEEA 139 Query: 315 YDP 317 ++P Sbjct: 140 FNP 142 >3CJR-A nrPDB Length = 254 Score = 31.6 bits (70), Expect = 0.57, Method: Composition-based stats. Identities = 24/154 (15%), Positives = 49/154 (31%), Gaps = 10/154 (6%) Query: 187 GFSTGYGAAVKTG------KVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK 240 F TG+ + ++PG + G G G+ I K G + +G+D++ Sbjct: 98 AFGTGHHETTRLALKALARHLRPGDKVLDLGTGS-GVLAIAAEKLGGKA--LGVDIDPMV 154 Query: 241 FEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGT 300 +A A + P+ + L + + H + + G Sbjct: 155 LPQAEANAKRNGVRPRFLEGSLEAALPFGPFDLLVANLYAELH-AALAPRYREALVPGGR 213 Query: 301 SVVVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGL 334 +++ G+ L + M R + G Sbjct: 214 ALLTGILKDRAPLVREAMAGAGFRPLEEAAEGEW 247 >3AOE-A nrPDB Length = 424 Score = 31.6 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 18/48 (37%) Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGID 235 F T AA K G G+ + G G VG + GA + D Sbjct: 203 FITAAAAAEKIGLQVEGARVAIQGFGNVGNAAARAFHDHGARVVAVQD 250 >5MMS-A nrPDB Length = 408 Score = 31.6 bits (70), Expect = 0.61, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 2/66 (3%) Query: 195 AVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATEC 252 A + G +KPG T + G G+GL++ + ++ ++ +K + A+GA Sbjct: 130 AERDGTLKPGDTIIEPTSGNTGIGLALAAAVRGYRCIIVMPEKMSSEKVDVLRALGAEIV 189 Query: 253 ISPKDS 258 +P ++ Sbjct: 190 RTPTNA 195 >4J90-A nrPDB Length = 222 Score = 31.6 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 26/61 (42%), Gaps = 4/61 (6%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPI 262 V GLG G S+ G ++ +D+N++K + AT + + + + + Sbjct: 7 KQFAVIGLGRFGGSICKELHRMG-HEVLAVDINEEKVNAYASY-ATHAVIANATEENELL 64 Query: 263 S 263 S Sbjct: 65 S 65 >2BHS-A nrPDB Length = 303 Score = 31.6 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 41/95 (43%), Gaps = 5/95 (5%) Query: 195 AVKTGKVKPGSTCVV---FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 A K G++KPG ++ G G+ L++I K ++ ++++++ A GA Sbjct: 52 AEKRGEIKPGD-VLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAEL 110 Query: 252 CISPKDST-KPISEVLSEMTGNNVGYTFEVIGHLE 285 + K+ + ++ EM G + + + Sbjct: 111 ILVTKEQGMEGARDLALEMANRGEGKLLDQFNNPD 145 >3HM2-A nrPDB Length = 178 Score = 31.6 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 49/134 (36%), Gaps = 10/134 (7%) Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEK----AMAVGAT 250 A+ KP T G GG G I +S + + ++++++ E+ A+ +G + Sbjct: 17 AISALAPKPHETLWDIG-GGSGSIAIEWLRSTPQTTAVCFEISEERRERILSNAINLGVS 75 Query: 251 ECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASC-HMNYGTSVVVGVPPS 309 + I+ + + + + N F G + A A G V V Sbjct: 76 DRIAVQQGAPRAFDDVPD----NPDVIFIGGGLTAPGVFAAAWKRLPVGGRLVANAVTVE 131 Query: 310 AKMLTYDPMLLFTG 323 ++ + + F G Sbjct: 132 SEQMLWALRKQFGG 145 >2AS0-A nrPDB Length = 396 Score = 31.6 bits (70), Expect = 0.66, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 19/48 (39%), Gaps = 6/48 (12%) Query: 201 VKPGSTC--VVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 V+PG V GG + AGA +IGID + E A Sbjct: 215 VQPGDRVLDVFTYTGGFAIHAA----IAGADEVIGIDKSPRAIETAKE 258 >3FBT-A nrPDB Length = 282 Score = 31.2 bits (69), Expect = 0.74, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 51/143 (35%), Gaps = 20/143 (13%) Query: 191 GYGAAVKTGKVK-PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK--------- 240 G+G + +V+ + CVV G GG +V+ K A I + N +K Sbjct: 108 GFGKMLSKFRVEIKNNICVVLGSGGAARAVLQYLKDNFAKDIYVVTRNPEKTSEIYGEFK 167 Query: 241 ---FEKAMAVGATECIS-------PKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDA 290 +++ + I+ PK+ P+ + + + V + + L Sbjct: 168 VISYDELSNLKGDVIINCTPKGMYPKEGESPVDKEVVAKFSSAVDLIYNPVETLFLKYAR 227 Query: 291 LASCHMNYGTSVVVGVPPSAKML 313 + G ++V +++ + Sbjct: 228 ESGVKAVNGLYMLVSQAAASEEI 250 >6J0Z-C nrPDB Length = 491 Score = 31.2 bits (69), Expect = 0.75, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 S VV G G GL + + AG S ++ +D + +++ A+G Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVS-VVVLDKLAEPIKESRALG 48 >3WGE-A nrPDB Length = 113 Score = 31.2 bits (69), Expect = 0.76, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 23/75 (30%), Gaps = 3/75 (4%) Query: 95 TVKPGDKVIPLFLPQCRECNACRNPDGNLC---IRSDITGRGVLADGTTRFTCKGKPVHH 151 V GD I F P C C A L S+ G + C G V Sbjct: 17 HVAQGDHFIKFFAPWCGHCKALAPTWEQLALGLEHSETVKIGKVDCTQHYELCSGNQVRG 76 Query: 152 FMNTSTFTEYTVVDE 166 + F + VD+ Sbjct: 77 YPTLLWFRDGKKVDQ 91 >6IQV-A nrPDB Length = 340 Score = 31.2 bits (69), Expect = 0.82, Method: Composition-based stats. Identities = 22/173 (12%), Positives = 51/173 (29%), Gaps = 24/173 (13%) Query: 206 TCVVFGLGGVGLSVI-----MGCKSAGASRIIGIDL-NKDKFEKAMAVGATE-------- 251 + G G +G +G KS+ + DL + + +T Sbjct: 4 KIGINGFGRIGRLAFRRILELGEKSSDIEVVAINDLTSPALLAHLLKYDSTHGTLNADVS 63 Query: 252 ------CISPKDS---TKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSV 302 ++ K+ +P ++ + + + V + E G T + V Sbjct: 64 ATDDSIVVNGKNYRVYAEPQAQNIPWVKNDGVDFVLECTG-FYTSKAKSQAHLDAGAKRV 122 Query: 303 VVGVPPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLD 355 ++ P + + T + T + + + F K+F + Sbjct: 123 LISAPAGSDLKTIVYNVNDDILTADDRIVSAGSCTTNCLAPLAFFENKEFGIK 175 >4PZE-A nrPDB Length = 284 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 8/38 (21%), Positives = 18/38 (47%), Gaps = 1/38 (2%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEK 243 T + G G +G + C G + ++ +D++ +K Sbjct: 5 TVGIVGAGTMGNGIAQACAVVGLN-VVMVDISDAAVQK 41 >3BKX-A nrPDB Length = 275 Score = 31.2 bits (69), Expect = 0.83, Method: Composition-based stats. Identities = 12/43 (27%), Positives = 21/43 (48%) Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDL 236 A + +VKPG + G G LS ++ + + + GID+ Sbjct: 34 AIAEAWQVKPGEKILEIGCGQGDLSAVLADQVGSSGHVTGIDI 76 >2ZJ1-A nrPDB Length = 495 Score = 31.2 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 20/137 (14%), Positives = 42/137 (30%), Gaps = 22/137 (16%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G ++ G G VG K GA R+ +++ +AM G + Sbjct: 275 GKKVLICGYGDVGKGCAEAMKGQGA-RVSVTEIDPINALQAMMEGFDVV--------TVE 325 Query: 264 EVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTG 323 E + + G+ + ++ ++ +G +D + G Sbjct: 326 EAI-----GDADIVVTATGNKDIIMLEHIKAMKDHAILGNIG--------HFDNEIDMAG 372 Query: 324 RTWKGCVFGGLKSRDDV 340 G +K + D+ Sbjct: 373 LERSGATRVNVKPQVDL 389 >4E4T-A nrPDB Length = 419 Score = 30.8 bits (68), Expect = 0.93, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 35/104 (33%), Gaps = 9/104 (8%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 PG+ + G G +G +S G R+ +D + A+ A + + Sbjct: 34 PGAWLGMVGGGQLGRMFCFAAQSMG-YRVAVLDPDPASPAGAV---ADRHLRAAYDDE-- 87 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCH--MNYGTSVVV 304 L+E+ G + E +D LA G V V Sbjct: 88 -AALAELAGLCEAVSTEFENVPAASLDFLARTTFVAPAGRCVAV 130 >3N58-A nrPDB Length = 464 Score = 30.8 bits (68), Expect = 0.95, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 28/77 (36%), Gaps = 3/77 (3%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 G VV G G VG AGA R+ +++ +A G D Sbjct: 246 AGKVAVVCGYGDVGKGSAQSLAGAGA-RVKVTEVDPICALQAAMDGFEVV--TLDDAAST 302 Query: 263 SEVLSEMTGNNVGYTFE 279 ++++ TGN T + Sbjct: 303 ADIVVTTTGNKDVITID 319 >1GPJ-A nrPDB Length = 404 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 27/65 (41%), Gaps = 5/65 (7%) Query: 193 GAAVKTGKVKPGS----TCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK-FEKAMAV 247 AAV+ + + GS T +V G G +G +V G ++ + ++ E A + Sbjct: 152 SAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYERAVELARDL 211 Query: 248 GATEC 252 G Sbjct: 212 GGEAV 216 >5ZBK-A nrPDB Length = 203 Score = 30.8 bits (68), Expect = 1.0, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 20/56 (35%), Gaps = 7/56 (12%) Query: 186 CGFSTGYGAAVKTGKVKPGSTCV------VFGLGGVGLSV-IMGCKSAGASRIIGI 234 CG S G + V G V+G G VGL + A +IGI Sbjct: 10 CGASPGASPVYQEAAVALGRHLAERGLTLVYGGGAVGLMGTVADAALAAGGEVIGI 65 >4IZO-A nrPDB Length = 419 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 35/102 (34%), Gaps = 5/102 (4%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 PG+ + G G +G ++ G R+ +D + A AV + D + Sbjct: 34 PGAWLGMVGGGQLGRMFCFAAQAMG-YRVAVLDPDPT--SPAGAVADKHLRAAYDDEAAL 90 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVV 304 +E+ V FE + A ++ G V + Sbjct: 91 AELAQLCD--AVSTEFENVPAASLDFLAQSTFVAPAGRCVAI 130 >5D84-A nrPDB Length = 326 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 10/57 (17%), Positives = 23/57 (40%), Gaps = 2/57 (3%) Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGID--LNKDKFEKAMAVGA 249 +K G + + + G +G+++ M K G +D ++ + + GA Sbjct: 58 GIKHGLITENTHLIESTSGNLGIALAMIAKIKGLKLTCVVDPKISPTNLKIIKSYGA 114 >5TQV-A nrPDB Length = 233 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 13/92 (14%), Positives = 31/92 (33%), Gaps = 4/92 (4%) Query: 205 STCVVFGLG-GVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT-ECISPKDSTKPI 262 T ++ G G+G + + G +I + A+GA + + I Sbjct: 10 KTVLIVGASRGLGREFVRQYQRDG-WNVIATARDDASLAALRALGAHAHALDITQPEQ-I 67 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASC 294 + + ++ G + V G + + + Sbjct: 68 AALGWKLDGERLDVAVVVSGVYGPRTEGVETI 99 >3TNL-A nrPDB Length = 315 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 24/68 (35%), Gaps = 3/68 (4%) Query: 190 TGY-GAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 TGY A + G G + G GG ++ + G I + D + A Sbjct: 139 TGYMRALKEAGHDIIGKKMTICGAGGAATAICIQAALDGVKEISIFNRKDDFYANAEKT- 197 Query: 249 ATECISPK 256 E I+ K Sbjct: 198 -VEKINSK 204 >3NJ4-A nrPDB Length = 435 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNK-DKFEKAMA 246 G VV G G VG + GA R+I +++ + + AM Sbjct: 215 AGKVAVVAGYGDVGKGCAQALRGFGA-RVIITEIDPINALQAAME 258 >6DLL-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 10/27 (37%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIG 233 + G G GL + AG II Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIV 34 >3GG9-A nrPDB Length = 352 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 35/79 (44%), Gaps = 3/79 (3%) Query: 189 STGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 ST G+V G T +FG G +G V ++ G + + + ++ E+A A G Sbjct: 145 STTMPPNFGIGRVLKGQTLGIFGYGKIGQLVAGYGRAFGMN--VLVWGRENSKERARADG 202 Query: 249 ATECISPKDSTKPISEVLS 267 KD+ S+VLS Sbjct: 203 F-AVAESKDALFEQSDVLS 220 >6GBN-A nrPDB Length = 438 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK-FEKAM 245 G VV G G VG + AGA R+I +++ + AM Sbjct: 218 AGKVAVVAGYGDVGKGSAASLRGAGA-RVIVTEIDPICALQAAM 260 >2NVU-B nrPDB Length = 805 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 3/70 (4%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 +V G GG+G ++ +G +I ID++ PKD +P +E Sbjct: 412 CKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQ---FLFRPKDIGRPKAE 468 Query: 265 VLSEMTGNNV 274 V +E + V Sbjct: 469 VAAEFLNDRV 478 >1YOV-B nrPDB Length = 444 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 3/70 (4%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 +V G GG+G ++ +G +I ID++ PKD +P +E Sbjct: 51 CKVLVIGAGGLGCELLKNLALSGFRQIHVIDMDTIDVSNLNRQ---FLFRPKDIGRPKAE 107 Query: 265 VLSEMTGNNV 274 V +E + V Sbjct: 108 VAAEFLNDRV 117 >4DIM-A nrPDB Length = 403 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 22/63 (34%), Gaps = 2/63 (3%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDK--FEKAMAVGATECISPKDSTKPI 262 ++ G G L + K G I G N K A + + +P + + + Sbjct: 8 KRLLILGAGRGQLGLYKAAKELGIHTIAGTMPNAHKPCLNLADEISYMDISNPDEVEQKV 67 Query: 263 SEV 265 ++ Sbjct: 68 KDL 70 >2EEZ-A nrPDB Length = 369 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 9/37 (24%), Positives = 18/37 (48%), Gaps = 1/37 (2%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFE 242 + V+ G G VG + GA ++ +D+N + + Sbjct: 168 SVVILGGGTVGTNAAKIALGMGA-QVTILDVNHKRLQ 203 >6GME-A nrPDB Length = 201 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 16/27 (59%) Query: 234 IDLNKDKFEKAMAVGATECISPKDSTK 260 +D+ ++ E A ++GAT I+ ++ Sbjct: 62 VDVREEGKENAFSLGATLWINSEEFED 88 >3OC4-A nrPDB Length = 452 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 12/28 (42%) Query: 193 GAAVKTGKVKPGSTCVVFGLGGVGLSVI 220 GA ++ T V G G +G+ I Sbjct: 136 GALAAVPLLENSQTVAVIGAGPIGMEAI 163 >2JC3-A nrPDB Length = 303 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 32/66 (48%), Gaps = 4/66 (6%) Query: 195 AVKTGKVKPGSTCVV---FGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251 A K G++KPG ++ G G+ L++I K ++ ++++++ A GA Sbjct: 52 AEKRGEIKPGD-VLIEATSGNTGIALAMIAALKGYRMKLLMPDNMSQERRAAMRAYGAEL 110 Query: 252 CISPKD 257 + K+ Sbjct: 111 ILVTKE 116 >3H9U-A nrPDB Length = 436 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNK-DKFEKAMA 246 G T V G G VG + GA R++ +++ + + AM Sbjct: 210 AGKTACVCGYGDVGKGCAAALRGFGA-RVVVTEVDPINALQAAME 253 >3DC2-A nrPDB Length = 529 Score = 30.4 bits (67), Expect = 1.4, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 13/28 (46%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRI 231 G T V GLG +G V + GA + Sbjct: 142 GKTVGVVGLGRIGQLVAQRIAAFGAYVV 169 >2RIR-A nrPDB Length = 300 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG 248 GS V GLG G+++ + GA+ + + + +G Sbjct: 157 GSQVAVLGLGRTGMTIARTFAALGAN-VKVGARSSAHLARITEMG 200 >2EXX-A nrPDB Length = 306 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 22/87 (25%), Positives = 33/87 (37%), Gaps = 10/87 (11%) Query: 207 CVVFGL-GGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV---GATECISPKDSTKPI 262 VVFG G G SV G ++ + N K + A + GA +D Sbjct: 14 VVVFGGTGAQGGSVARTLLEDGTFKVRVVTRNPRK-KAAKELRLQGAEVVQGDQD----- 67 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMID 289 +V+ E+ N TF V + E+ Sbjct: 68 DQVIMELALNGAYATFIVTNYWESCSQ 94 >3OND-A nrPDB Length = 488 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 19/42 (45%), Gaps = 1/42 (2%) Query: 203 PGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKA 244 G VV G G VG K AGA R+I +++ +A Sbjct: 264 AGKVAVVAGYGDVGKGCAAALKQAGA-RVIVTEIDPICALQA 304 >1QO8-A nrPDB Length = 566 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 16/32 (50%), Gaps = 1/32 (3%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNK 238 +V G G G + + K AGA+ +I +D Sbjct: 124 VLVVGAGSAGFNASLAAKKAGAN-VILVDKAP 154 >4F86-A nrPDB Length = 320 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 25/64 (39%), Gaps = 6/64 (9%) Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEK----AMAVGATEC 252 G V PG T V G G G V+ ++ G+ L+ + E A +G + Sbjct: 119 HLGPVGPGDTLVDAGCGRGGSMVM--AHQRFGCKVEGVTLSAAQAEFGNRRARELGIDDH 176 Query: 253 ISPK 256 + + Sbjct: 177 VRSR 180 >3HDH-A nrPDB Length = 302 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 32/91 (35%), Gaps = 7/91 (7%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 V G G +G + + G ++ +D +D K+ G E + K + Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK-GIEESL-----RKVAKK 68 Query: 265 VLSEMTGNNVGYTFEVIGHLETMIDALASCH 295 +E + + + + T DA + H Sbjct: 69 KFAENPKAGDEFVEKTLSSISTSTDAASVVH 99 >2BRY-A nrPDB Length = 497 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIG 233 + G+ + C+V G G GL + GA ++ Sbjct: 82 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 121 >4X4J-A nrPDB Length = 507 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/101 (17%), Positives = 39/101 (38%), Gaps = 6/101 (5%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT----ECISPKDSTKPI 262 V+ G G GL + + AG ++ ++ + ++ +G T E + + Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIG-VVVLERLPARTGESRGLGFTARTMEVFDQRGLLRRF 83 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVV 303 EV + G+ G + G L+ A + + +V+ Sbjct: 84 GEVQTSDQGHFGGIPVDF-GLLDGAHQAAKTIPQSATEAVL 123 >4TXK-A nrPDB Length = 615 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 16/40 (40%) Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIG 233 + G+ + C+V G G GL + GA ++ Sbjct: 74 PVYQQGQACTNTKCLVVGAGPCGLRAAVELALLGARVVLV 113 >3EMK-A nrPDB Length = 246 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 36/87 (41%), Gaps = 11/87 (12%) Query: 204 GSTCVVFGL-GGVGLSVIMGCKSAGASRIIGI-DLNKDKF-EKAMAVGATECISP----- 255 G +V G GG+G ++ + GA I+G+ ++K E A +G + P Sbjct: 7 GRKALVTGATGGLGEAIARALHAQGA--IVGLHGTREEKLKELAAELGERIFVFPANLSD 64 Query: 256 KDSTKPISEVLSEMTGNNVGYTFEVIG 282 +++ K + + E G V G Sbjct: 65 REAVKALGQKAEEEMG-GVDILVNNAG 90 >1PBY-A nrPDB Length = 489 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 14/79 (17%) Query: 19 VIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVSKFPVIV 78 VI + A + P + +E ++++ TG+ +D + +G Sbjct: 262 VIGGRLAAVKADAAPQVLAVAPARLKIGEETQLRVAGTGL-GSDLTLPEG---------- 310 Query: 79 GHEATGIVESIGEGVTTVK 97 G VES G GVT +K Sbjct: 311 ---VAGSVESAGNGVTVLK 326 >5WAB-A nrPDB Length = 751 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 9/21 (42%), Positives = 12/21 (57%) Query: 69 TMVSKFPVIVGHEATGIVESI 89 S+ P + GHEA GIV + Sbjct: 123 EYWSEDPYLAGHEAVGIVAGV 143 >3GRP-A nrPDB Length = 266 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 5/60 (8%) Query: 204 GSTCVVFGL-GGVGLSVIMGCKSAGASRIIGI-DLNKDKF-EKAMAVGATECISPKDSTK 260 G +V G GG+G ++ + GA I+G+ +DK E A +G + + + Sbjct: 27 GRKALVTGATGGIGEAIARCFHAQGA--IVGLHGTREDKLKEIAADLGKDVFVFSANLSD 84 >1HL3-A nrPDB Length = 358 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 14/24 (58%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAG 227 G T + GLG VG +V + K+ G Sbjct: 171 GETLGIIGLGRVGQAVALRAKAFG 194 >1G6Q-1 nrPDB Length = 328 Score = 30.0 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 23/54 (42%), Gaps = 3/54 (5%) Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 247 A ++ + + G G G+ + K GA +IG+D++ E A + Sbjct: 29 AIIQNKDLFKDKIVLDVGCGT-GILSMFAAKH-GAKHVIGVDMSSI-IEMAKEL 79 >1DOD-A nrPDB Length = 394 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 7/26 (26%), Positives = 10/26 (38%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRII 232 + G G GL + AG +I Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVI 30 >1LTH-T nrPDB Length = 319 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 201 VKPGSTCVVFGLGGVGLSVIMGCKSAG-ASRIIGIDLNKDKFEK 243 VKP + V G G VG ++ G A I+ D+ K++ E Sbjct: 5 VKP-TKLAVIGAGAVGSTLAFAAAQRGIAREIVLEDIAKERVEA 47 >5NMX-A nrPDB Length = 425 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 11/27 (40%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRII 232 V G G GL+ K AG ++ Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGFEVMV 29 >2YQ5-A nrPDB Length = 343 Score = 29.7 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 17/31 (54%), Gaps = 1/31 (3%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDL 236 T + G+G +G +V + GA ++I D+ Sbjct: 150 TVGLIGVGHIGSAVAEIFSAMGA-KVIAYDV 179 >6HNS-A nrPDB Length = 454 Score = 29.7 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 10/27 (37%), Gaps = 3/27 (11%) Query: 206 TCVVFGLGGVGLS---VIMGCKSAGAS 229 + G G GL+ + GA+ Sbjct: 4 RVAIIGAGPCGLAQLRAFQSAAAKGAA 30 >3HWR-A nrPDB Length = 318 Score = 29.7 bits (65), Expect = 2.4, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 27/102 (26%), Gaps = 5/102 (4%) Query: 204 GSTCVVFGLGGVGL-SVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 G + G G VG M ++ +I I + A G D + Sbjct: 19 GMKVAIMGAGAVGCYYGGMLARA--GHEVILIAR-PQHVQAIEATGLRLETQSFDEQVKV 75 Query: 263 SEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVV 304 S + +T ALA S +V Sbjct: 76 SASSDPSAVQGADLVLFCVKSTDTQSAALAM-KPALAKSALV 116 >3H8E-A nrPDB Length = 497 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 16/81 (19%), Positives = 28/81 (34%), Gaps = 1/81 (1%) Query: 220 IMGCKSAG-ASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVGYTF 278 K G A + + +++ +K K + +GA + P VL+ G F Sbjct: 203 AEQAKELGKAHKALKVEVLDEKKIKDLGMGAFYAVGQGSDQPPRLIVLNYQGGKKADKPF 262 Query: 279 EVIGHLETMIDALASCHMNYG 299 ++G T S G Sbjct: 263 VLVGKGITFDTGGISLKPGAG 283 >4FHN-X nrPDB Length = 450 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 23/78 (29%), Gaps = 8/78 (10%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G V G G V I GA I D + + G T K+ + Sbjct: 235 GMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVD---ESGFT-----KEKLARLI 286 Query: 264 EVLSEMTGNNVGYTFEVI 281 E+ S G Y E Sbjct: 287 EIKSSRDGRVADYAKEFG 304 >3IC9-A nrPDB Length = 492 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 41/132 (31%), Gaps = 7/132 (5%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGA-SRIIGIDLNKDKF--EKAMAVGATECISPKDSTKP 261 + VFG G +GL + G ++ G + E+ A + + + Sbjct: 175 KSVAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRY-AEKTFNEEFYFDA 233 Query: 262 ISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVV---GVPPSAKMLTYDPM 318 + V+S + + + ++ G V G+ ++ L Sbjct: 234 KARVISTIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNS 293 Query: 319 LLFTGRTWKGCV 330 LF T + V Sbjct: 294 PLFDELTLQTSV 305 >3H5A-A nrPDB Length = 358 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 16/30 (53%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGID 235 V+ G GG+G V + ++G II ID Sbjct: 117 KVVILGCGGIGNHVSVILATSGIGEIILID 146 >2D1F-A nrPDB Length = 360 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 31/97 (31%), Gaps = 10/97 (10%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLN-KDKFEKAMAVGATE----CISPK-- 256 G TC V G + ++II ID N D E A + A ++ Sbjct: 108 GITCAVLIPQGKIAMGKLAQAVMHGAKIIQIDGNFDDCLELARKMAADFPTISLVNSVNP 167 Query: 257 ---DSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDA 290 + K + + ++ G +G+ + Sbjct: 168 VRIEGQKTAAFEIVDVLGTAPDVHALPVGNAGNITAY 204 >1F14-A nrPDB Length = 310 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 16/42 (38%), Gaps = 1/42 (2%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMA 246 V G G +G + + G ++ +D +D K+ Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATG-HTVVLVDQTEDILAKSKK 56 >5B2L-A nrPDB Length = 324 Score = 29.7 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 19/85 (22%) Query: 14 GTAGKVIKCKA----AVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGI----------- 58 G +G+++ KA A P I+ + P ++R + + GI Sbjct: 162 GISGRLVDSKAKTRSAGCAAYMAPERIDPPDPTKP-DYDIRADVWSLGISLVELATGQFP 220 Query: 59 ---CRTDDHVIKGTMVSKFPVIVGH 80 C+TD V+ + + P++ GH Sbjct: 221 YKNCKTDFEVLTKVLQEEPPLLPGH 245 >4XRR-A nrPDB Length = 456 Score = 29.3 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 20/142 (14%), Positives = 42/142 (29%), Gaps = 6/142 (4%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEV 265 V+ G G VG + + GA ++ +D + A C P+ Sbjct: 17 KVVIAGAGYVGTCLAVTLAGRGA-EVVAVDSDPGTVADLR---AGRCRLPEPGLAGAVRD 72 Query: 266 LSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLLFTGRT 325 L+ +++ +G + +I + + V + + + P L Sbjct: 73 LAATGRLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQLVAACE--QIAPRLRAGQLV 130 Query: 326 WKGCVFGGLKSRDDVPKLVTEF 347 +R V L+ Sbjct: 131 ILKSTVSPGTTRTLVAPLLESG 152 >6BQC-A nrPDB Length = 383 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 22/131 (16%), Positives = 49/131 (37%), Gaps = 18/131 (13%) Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASR----IIGIDLNKDKFEKAMAV--GAT 250 + ++KPG + G G GL+ AS ++G+ ++ ++ + A G Sbjct: 162 EKLQLKPGMRVLDIGCGWGGLA------HYMASNYDVSVVGVTISAEQQKMAQERCEGLD 215 Query: 251 ECISPKDSTKPISEVLSEMTGNNVGYTFEVIG--HLETMIDALASCHMNYGTSVVVGVPP 308 I +D +++ + + FE +G + +T + G ++ + Sbjct: 216 VTILLQDYRD-LNDQFDRIVSVGM---FEHVGPKNYDTYFAVVDRNLKPEGIFLLHTIGS 271 Query: 309 SAKMLTYDPML 319 L DP + Sbjct: 272 KKTDLNVDPWI 282 >5VMT-A nrPDB Length = 342 Score = 29.3 bits (64), Expect = 3.1, Method: Composition-based stats. Identities = 19/167 (11%), Positives = 43/167 (25%), Gaps = 19/167 (11%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGI---------------DLNKDKFEKAMAVGAT 250 + G G +G + + A + + D + +F+ + Sbjct: 12 KVAINGFGRIGRLALRQIEKAHGIEVAAVNDLTPAEMLLHLFKYDSTQGRFQGTAELKDD 71 Query: 251 E-CISPKDSTKPISEVLSEMTGN--NVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVP 307 ++ ++ + E+ V E G T + VV+ P Sbjct: 72 AIVVNGREIKVFANPNPEELPWGELGVDVVLECTGFF-TNKTKAEAHIRAGARKVVISAP 130 Query: 308 PSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDL 354 + T + V + + L K+F + Sbjct: 131 GGNDVKTVVYGVNQDILDGSETVISAASCTTNCLAPMAAVLQKEFGV 177 >5XGV-A nrPDB Length = 462 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 8/28 (28%), Positives = 13/28 (46%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRII 232 T ++ G G VGL + AG ++ Sbjct: 2 DTVIIAGGGPVGLMLACELGLAGVDTVV 29 >2LDB-A nrPDB Length = 317 Score = 29.3 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 15/38 (39%), Positives = 20/38 (52%), Gaps = 1/38 (2%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAG-ASRIIGIDLNKDK 240 G+ VV G G VG S + + G A I+ ID N+ K Sbjct: 6 GARVVVIGAGFVGASYVFALMNQGIADEIVLIDANESK 43 >5OHX-A nrPDB Length = 504 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 6/69 (8%) Query: 195 AVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGI--DLNKDKFEKAMAVGAT 250 A G +KPG T + G G+GL M G II + ++ +K A+GA Sbjct: 89 AEDKGLLKPGCTIIEPTSGNTGIGL--AMAAAVRGYKCIIVMPEKMSDEKISTLYALGAK 146 Query: 251 ECISPKDST 259 +P +++ Sbjct: 147 IIRTPTEAS 155 >3FEO-A nrPDB Length = 437 Score = 28.9 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 6/23 (26%), Positives = 10/23 (43%) Query: 56 TGICRTDDHVIKGTMVSKFPVIV 78 IC +D H + S P++ Sbjct: 93 CNICGSDIHPVGWCAASGKPLVP 115 >3ZZN-A nrPDB Length = 310 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 22/58 (37%), Gaps = 5/58 (8%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASR-IIGIDLNKDKFEKAMAVGATECISPKDSTKPI 262 + G G VG + G +R ++ +DL K +A A + + P+ Sbjct: 2 KVGIVGSGMVGSATAYALALLGVAREVVLVDL-DRKLAQA---HAEDILHATPFAHPV 55 >3LLV-A nrPDB Length = 141 Score = 28.9 bits (63), Expect = 3.6, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 36/110 (32%), Gaps = 7/110 (6%) Query: 208 VVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVL- 266 +V G G+ ++ +AG +++ +D +K+K E G I P E Sbjct: 10 IVIGSEAAGVGLVRELTAAG-KKVLAVDKSKEKIELLEDEGFDAVI-----ADPTDESFY 63 Query: 267 SEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYD 316 + V E + L + +V V K ++ Sbjct: 64 RSLDLEGVSAVLITGSDDEFNLKILKALRSVSDVYAIVRVSSPKKKEEFE 113 >5JFC-L nrPDB Length = 474 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 10/31 (32%) Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRII 232 + G + G G GL+ G I Sbjct: 152 RNGKKVAIIGAGPAGLTCAADLAKMGYEVTI 182 >3AOE-E nrPDB Length = 419 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 7/64 (10%) Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLN------KDKFEKAMAVG 248 A + G G+ VV GLG VG +V + + G R++ + + + + A + Sbjct: 209 AKRRGLDLRGARVVVQGLGQVGAAVALHAERLGM-RVVAVATSMGGMYAPEGLDVAEVLS 267 Query: 249 ATEC 252 A E Sbjct: 268 AYEA 271 >4PRK-A nrPDB Length = 336 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 17/32 (53%), Gaps = 1/32 (3%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDL 236 T + G+G +G +V + GA +++ D+ Sbjct: 147 KTIGLIGVGHIGSAVAQIFSAMGA-KVLAYDV 177 >3K8Z-A nrPDB Length = 423 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 45/138 (32%), Gaps = 11/138 (7%) Query: 194 AAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDL-----NKDKFEKAMAVG 248 AA K G G+ VV G G G + AGA + D + + + Sbjct: 210 AAKKRGIDIKGARVVVQGFGNAGSYLAKFMHDAGAKVVGISDAYGGLYDPEGLDI----- 264 Query: 249 ATECISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPP 308 + +DS ++++ ++ N + + I+ + + + V Sbjct: 265 -DYLLDRRDSFGTVTKLFNDTITNQELLELDCDILVPAAIENQITEENAHNIRAKIVVEA 323 Query: 309 SAKMLTYDPMLLFTGRTW 326 + T + + + R Sbjct: 324 ANGPTTLEGTKILSDRDI 341 >2YFH-A nrPDB Length = 448 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 17/78 (21%), Positives = 23/78 (29%), Gaps = 8/78 (10%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G V G G V I GA I D + + G T K+ + Sbjct: 231 GMRVSVSGSGNVAQYAIEKAMEFGARVITASDSSGTVVD---ESGFT-----KEKLARLI 282 Query: 264 EVLSEMTGNNVGYTFEVI 281 E+ + G Y E Sbjct: 283 EIKASRDGRVADYAKEFG 300 >5VJ7-A nrPDB Length = 476 Score = 28.9 bits (63), Expect = 4.0, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 10/31 (32%) Query: 202 KPGSTCVVFGLGGVGLSVIMGCKSAGASRII 232 + G + G G GL+ G I Sbjct: 152 RNGKKVAIIGAGPAGLTCAADLAKMGYEVTI 182 >4RDI-A nrPDB Length = 288 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 17/45 (37%) Query: 197 KTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKF 241 K ++ + V G+GGVG G I ID++ Sbjct: 43 KALQLFADAHICVVGIGGVGSWAAEALARTGIGAITLIDMDDVCV 87 >4OFX-A nrPDB Length = 319 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 36/79 (45%), Gaps = 10/79 (12%) Query: 194 AAVKTGKVKPGSTCV--VFGLGGVGLSVIMGCKSAGASRIIGI---DLNKDKFEKAMAVG 248 +A K GK+KPG T + G G+G I + R+I ++ +K A+G Sbjct: 56 SAEKQGKIKPGDTLIEPTSGNTGIG---IALAGAVKGYRVIITMPEKMSHEKQVVLEALG 112 Query: 249 ATECISPKDS--TKPISEV 265 AT +P ++ P S + Sbjct: 113 ATIYRTPTEAAYDDPESHI 131 >3VH2-A nrPDB Length = 616 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 30/92 (32%), Gaps = 23/92 (25%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGID------LNKDKFEKAMAVGATECISPKDST 259 ++ G G +G V + G +I +D N + + +D Sbjct: 329 KVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQAL---------YNFEDCG 379 Query: 260 KPISE--------VLSEMTGNNVGYTFEVIGH 283 KP +E + M V + +IGH Sbjct: 380 KPKAELAAASLKRIFPLMDATGVKLSIPMIGH 411 >3T7E-A nrPDB Length = 344 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 30/92 (32%), Gaps = 23/92 (25%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGID------LNKDKFEKAMAVGATECISPKDST 259 ++ G G +G V + G +I +D N + + +D Sbjct: 40 KVLLLGAGTLGCYVSRALIAWGVRKITFVDNGTVSYSNPVRQAL---------YNFEDCG 90 Query: 260 KPISE--------VLSEMTGNNVGYTFEVIGH 283 KP +E + M V + +IGH Sbjct: 91 KPKAELAAASLKRIFPLMDATGVKLSIPMIGH 122 >3PPI-A nrPDB Length = 281 Score = 28.9 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 13/84 (15%), Positives = 29/84 (34%), Gaps = 4/84 (4%) Query: 204 GSTCVVFG-LGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVG--ATEC-ISPKDST 259 G++ +V G GG+G + + + G +I + A +G A + Sbjct: 30 GASAIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVSTNVTSED 89 Query: 260 KPISEVLSEMTGNNVGYTFEVIGH 283 ++ + + + Y G Sbjct: 90 SVLAAIEAANQLGRLRYAVVAHGG 113 >1BG6-A nrPDB Length = 359 Score = 28.5 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 28/154 (18%), Positives = 53/154 (34%), Gaps = 8/154 (5%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 T V GLG G + G S ++ D++ + ++ GA P + + Sbjct: 5 KTYAVLGLGNGGHAFAAYLALKGQS-VLAWDIDAQRIKEIQDRGAIIAEGPGLAGTAHPD 63 Query: 265 VLSEMTGNNV---GYTFEVIGHL-ETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL 320 +L+ G V V+ + I A + +++ G +++ + L + +L Sbjct: 64 LLTSDIGLAVKDADVILIVVPAIHHASIAANIASYISEGQLIILNPGATGGALEFRKILR 123 Query: 321 FTG---RTWKGCVFGGLKSRDDVPKLVTEFLAKK 351 G T R + P VT K Sbjct: 124 ENGAPEVTIGETSSMLFTCRSERPGQVTVNAIKG 157 >3RWB-A nrPDB Length = 247 Score = 28.5 bits (62), Expect = 4.9, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 33/83 (39%), Gaps = 11/83 (13%) Query: 203 PGSTCVVFGLG-GVGLSVIMGCKSAGASRIIGIDLNKDKF--------EKAMAVGATECI 253 G T +V G G+G ++ + GA +I D+N + +KA A+ A Sbjct: 5 AGKTALVTGAAQGIGKAIAARLAADGA-TVIVSDINAEGAKAAAASIGKKARAIAAD-IS 62 Query: 254 SPKDSTKPISEVLSEMTGNNVGY 276 P +E+ + G ++ Sbjct: 63 DPGSVKALFAEIQALTGGIDILV 85 >5UOG-A nrPDB Length = 344 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 24/146 (16%), Positives = 46/146 (31%), Gaps = 20/146 (13%) Query: 204 GSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPIS 263 G T +FGLG +GL++ ++ G S A +P++ Sbjct: 164 GRTVGLFGLGRIGLAIARRLEAFGVSI------------------AYHTRTPREGLGFTY 205 Query: 264 EVLSEMTGNNVGYTFEVI-GHLETMIDALASCHMNYG-TSVVVGVPPSAKMLTYDPMLLF 321 V ++ G T+ A G V++ V + + + Sbjct: 206 HPTLVGMAEAVDTLIVIVPGTASTLKAVNADVLSALGPKGVLINVGRGSTVDEAALVTAL 265 Query: 322 TGRTWKGCVFGGLKSRDDVPKLVTEF 347 T G ++ +VP+ + F Sbjct: 266 QNGTIAGAGLDVFENEPNVPEALLSF 291 >2UVD-A nrPDB Length = 246 Score = 28.5 bits (62), Expect = 5.1, Method: Composition-based stats. Identities = 25/134 (18%), Positives = 43/134 (32%), Gaps = 10/134 (7%) Query: 216 GLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTGNNVG 275 G ++ S G R I ID A GA ++ + + +EV+ E+ Sbjct: 4 GKVALVTGASRGIGRAIAID-------LAKQ-GANVVVNYAGNEQKANEVVDEIKKLGSD 55 Query: 276 YTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPMLL-FTGRTWKGCVFGGL 334 V + D V + + +T D +L+ W + L Sbjct: 56 -AIAVRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVTKDNLLMRMKEEEWDTVINTNL 114 Query: 335 KSRDDVPKLVTEFL 348 K K V+ F+ Sbjct: 115 KGVFLCTKAVSRFM 128 >6FZI-A nrPDB Length = 332 Score = 28.5 bits (62), Expect = 5.2, Method: Composition-based stats. Identities = 25/170 (14%), Positives = 44/170 (25%), Gaps = 21/170 (12%) Query: 206 TCVVFGLGGVGLSVIMGCKSAGASRIIGI-DLNKDK-FEKAMAV---------------G 248 + G G +G + ++ I DL K G Sbjct: 3 KVAINGFGRIGRLALRLMIDNPEFEVVAINDLTDAKTLAHLFKYDSAQGRFNGEIEVKEG 62 Query: 249 ATECISPKDSTKPISEVLSEMTGN--NVGYTFEVIGHLETMIDALASCHMNYGTSVVVGV 306 A ++ K+ +E+ V E G + A A VV+ Sbjct: 63 A-FVVNGKEIKVTAKSNPAELPWGELGVDVVLECTGFFASKEKASAHLTAG-AKKVVISA 120 Query: 307 PPSAKMLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQ 356 P + T + V G + + + L F L++ Sbjct: 121 PAGNDLPTVVYNVNHDILDGSEDVISGASCTTNCLAPMAKALNDNFGLNK 170 >3MOG-A nrPDB Length = 483 Score = 28.5 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 9/52 (17%), Positives = 24/52 (46%), Gaps = 2/52 (3%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK 256 T V G G +G + I ++ +++ D++ + +A+ G ++ + Sbjct: 6 QTVAVIGSGTMG-AGIAEVAASHGHQVLLYDISAEALTRAID-GIHARLNSR 55 >3JTM-A nrPDB Length = 351 Score = 28.5 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 28/76 (36%), Gaps = 3/76 (3%) Query: 191 GYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGAT 250 G A + ++ G T G G +G ++ K G ++ D + E GA Sbjct: 152 VAGIAYRAYDLE-GKTIGTVGAGRIGKLLLQRLKPFG-CNLLYHDRLQMAPELEKETGAK 209 Query: 251 ECISPKDSTKPISEVL 266 + + P +V+ Sbjct: 210 -FVEDLNEMLPKCDVI 224 >4FXS-A nrPDB Length = 496 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 33/88 (37%), Gaps = 9/88 (10%) Query: 225 SAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPISEVLSEMTGNNVGYTFEVIG 282 + GA+ N+++ + + G + S ++ + + + E E+IG Sbjct: 225 AVGAAP-----GNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYP--HLEIIG 277 Query: 283 HLETMIDALASCHMNYGTSVVVGVPPSA 310 + + ++V VG+ P + Sbjct: 278 GNVATAEGARALIEAGVSAVKVGIGPGS 305 >4X28-D nrPDB Length = 373 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 26/87 (29%), Gaps = 10/87 (11%) Query: 150 HHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVV 209 H + T T T+ + + + G AV Sbjct: 141 HGYRLTGTRTQVGYGPVADAFLVPAETDSGAAVFLVAAGDPGV--AVTA--------LAT 190 Query: 210 FGLGGVGLSVIMGCKSAGASRIIGIDL 236 GLG VG + G K A R+ G D+ Sbjct: 191 TGLGSVGHLELNGAKVDAARRVGGTDV 217 >4FEZ-A nrPDB Length = 388 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 13/88 (14%), Positives = 33/88 (37%), Gaps = 9/88 (10%) Query: 225 SAGASRIIGIDLNKDKFEKAMAVGATECI--SPKDSTKPISEVLSEMTGNNVGYTFEVIG 282 + GA+ N+++ + + G + S ++ + + + E E+IG Sbjct: 124 AVGAAP-----GNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAAYP--HLEIIG 176 Query: 283 HLETMIDALASCHMNYGTSVVVGVPPSA 310 + + ++V VG+ P + Sbjct: 177 GNVATAEGARALIEAGVSAVKVGIGPGS 204 >1LSS-A nrPDB Length = 140 Score = 28.1 bits (61), Expect = 6.5, Method: Composition-based stats. Identities = 22/100 (22%), Positives = 31/100 (31%) Query: 172 IDDAAPPEKVCLIGCGFSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRI 231 I A E L+ G T G V G V L + KS G ++ Sbjct: 39 ICKKASAEIDALVINGDCTKIKTLEDAGIEDADMYIAVTGKEEVNLMSSLLAKSYGINKT 98 Query: 232 IGIDLNKDKFEKAMAVGATECISPKDSTKPISEVLSEMTG 271 I + + +G +SP+ E L E G Sbjct: 99 IARISEIEYKDVFERLGVDVVVSPELIAANYIEKLIERPG 138 >4EJ0-A nrPDB Length = 342 Score = 28.1 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 55/162 (33%), Gaps = 12/162 (7%) Query: 206 TCVVFGLGG-VGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDSTKPISE 264 T +V G G +G +++ G +RII +D N + +K + E D T+ + E Sbjct: 14 TLIVTGAAGFIGANLVKALNERGETRIIAVD-NLTRADKFKNLVDCEIDDYLDKTEFV-E 71 Query: 265 VLSEMTGNNVGYTFEVIGHLETMIDALASC---HMNYGTSVVVGVPPSAKMLTYDPMLLF 321 + V F +TM + Y +V+ L Sbjct: 72 RFARGDFGKVRAVFHEGACSDTMETDGRYMMDNNFRYSRAVLDACLAQGAQ-----FLYA 126 Query: 322 TGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLP 363 + G +V + + KF DQ+I V+P Sbjct: 127 SSAAIYGG-SSRFVEEREVEAPLNVYGYSKFLFDQVIRRVMP 167 >1WG8-A nrPDB Length = 285 Score = 28.1 bits (61), Expect = 7.0, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 188 FSTGYGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAV 247 Y A+ V+PG V LGG G + + + R+IG+D + + +A + Sbjct: 7 VPVLYQEALDLLAVRPGGVYVDATLGGAGHARGILER---GGRVIGLDQDPEAVARAKGL 63 Query: 248 G 248 Sbjct: 64 H 64 >5MKK-A nrPDB Length = 611 Score = 28.1 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 23/53 (43%), Gaps = 6/53 (11%) Query: 200 KVKPGSTCVVFGLGGVGLSVI--MGCKSA----GASRIIGIDLNKDKFEKAMA 246 +V+PG + G G G + + + + G + G+D+ + + E+ Sbjct: 381 RVRPGEKVALVGATGAGKTSVVSLIARFYDPQRGCVFLDGVDVRRYRQEELRR 433 >4LRT-B nrPDB Length = 323 Score = 28.1 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 18/121 (14%), Positives = 37/121 (30%), Gaps = 14/121 (11%) Query: 204 GSTCV-VFGLGGVG---LSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPKDST 259 G + G G +G L + + ++G+D + +A +G + + Sbjct: 22 GKAVAAIVGPGNIGTDLLIKLQRSEHIEVRYMVGVDPASEGLARARKLGVE---ASAEGV 78 Query: 260 KPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAKMLTYDPML 319 + E FE + +A G + + P + L P+ Sbjct: 79 DWLLEQ-----DELPDLVFEATSAKAHLANAPRYAEA--GITAIDLTPAAVGPLVCPPVN 131 Query: 320 L 320 L Sbjct: 132 L 132 >3NIX-A nrPDB Length = 421 Score = 28.1 bits (61), Expect = 7.5, Method: Composition-based stats. Identities = 10/61 (16%), Positives = 16/61 (26%), Gaps = 11/61 (18%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASR-----------IIGIDLNKDKFEKAMAVGATECISP 255 +V G G G +G +IG L E G + + Sbjct: 8 VLVIGAGPAGTVAASLVNKSGFKVKIVEKQKFPRFVIGESLLPRCMEHLDEAGFLDAVKA 67 Query: 256 K 256 + Sbjct: 68 Q 68 >5UJU-A nrPDB Length = 576 Score = 27.7 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 7/58 (12%), Positives = 14/58 (24%), Gaps = 4/58 (6%) Query: 231 IIGIDLNKDKFEKAMAVGATE----CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHL 284 +I D + A + A + I V + + G + Sbjct: 463 VIATDSTAQSLDLAGEIAAEHGALTLSVYSTADDVIDAAHEAAVRGGVALSINLTGGV 520 >3NNK-A nrPDB Length = 411 Score = 27.7 bits (60), Expect = 8.4, Method: Composition-based stats. Identities = 6/30 (20%), Positives = 12/30 (40%) Query: 195 AVKTGKVKPGSTCVVFGLGGVGLSVIMGCK 224 A+ ++PG +V G G + + Sbjct: 79 AILVSAIRPGDKVLVPVFGRFGHLLCEIAR 108 >3FG2-P nrPDB Length = 404 Score = 27.7 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 7/23 (30%), Positives = 10/23 (43%) Query: 205 STCVVFGLGGVGLSVIMGCKSAG 227 VV G G +GL ++ G Sbjct: 143 KHVVVIGAGFIGLEFAATARAKG 165 >4P4L-A nrPDB Length = 277 Score = 27.7 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 23/49 (46%) Query: 208 VVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATECISPK 256 +V G GG + ++G G + I + N DK + + +G ++ + Sbjct: 121 LVLGSGGTAPAAVVGLAELGVTDITVVARNSDKAARLVDLGTRVGVATR 169 >1V9C-A nrPDB Length = 218 Score = 27.7 bits (60), Expect = 9.2, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 35/104 (33%), Gaps = 10/104 (9%) Query: 216 GLSVIM-GCKSAGASRIIGIDLNKDKFEK----AMAVGATECISPKD----STKPISEVL 266 GL I G + +R+I LN ++ + + A + + T+ + V Sbjct: 59 GLKAIQAGARILVDARMIACGLNPERLRLFGNEVVELLAHPEVVARAKATGGTRAEAAVA 118 Query: 267 SEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVV-GVPPS 309 + +G+ T + AL +V G+P Sbjct: 119 YAWEKGLLDGAIVGVGNAPTFLLALVEAIRQGARPALVLGMPVG 162 >4KUG-A nrPDB Length = 290 Score = 27.7 bits (60), Expect = 9.3, Method: Composition-based stats. Identities = 7/35 (20%), Positives = 15/35 (42%), Gaps = 1/35 (2%) Query: 205 STCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKD 239 V G G +G ++ + G +I D+ ++ Sbjct: 2 KKVFVLGAGTMGAGIVQAFAAKG-CEVIVRDIKEE 35 >2A33-A nrPDB Length = 215 Score = 27.7 bits (60), Expect = 9.6, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 24/56 (42%), Gaps = 7/56 (12%) Query: 186 CGFSTGYGAAVKTGKVKPGSTCV------VFGLGGVGLSV-IMGCKSAGASRIIGI 234 CG S G ++ + V G+ V V+G G +GL + G +IGI Sbjct: 20 CGSSQGKKSSYQDAAVDLGNELVSRNIDLVYGGGSIGLMGLVSQAVHDGGRHVIGI 75 >1QP8-A nrPDB Length = 303 Score = 27.7 bits (60), Expect = 9.7, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 20/48 (41%), Gaps = 2/48 (4%) Query: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKD 239 YG V+ ++ G V GLG +G V + GA ++ G Sbjct: 113 YGRDVEIPLIQ-GEKVAVLGLGEIGTRVGKILAALGA-QVRGFSRTPK 158 >3II4-A nrPDB Length = 466 Score = 27.3 bits (59), Expect = 10.0, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 9/27 (33%) Query: 207 CVVFGLGGVGLSVIMGCKSAGASRIIG 233 VV G G G + G S I Sbjct: 8 VVVLGAGPGGYVAAIRAAQLGLSTAIV 34 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.133 0.367 Lambda K H 0.267 0.0407 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,180,975 Number of Sequences: 36641 Number of extensions: 650305 Number of successful extensions: 3506 Number of sequences better than 10.0: 333 Number of HSP's better than 10.0 without gapping: 290 Number of HSP's successfully gapped in prelim test: 166 Number of HSP's that attempted gapping in prelim test: 2575 Number of HSP's gapped (non-prelim): 522 length of query: 386 length of database: 10,336,785 effective HSP length: 99 effective length of query: 287 effective length of database: 6,709,326 effective search space: 1925576562 effective search space used: 1925576562 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.7 bits)