BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P39683 (429 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1VLP-A nrPDB 891 0.0 1YIR-A nrPDB 211 4e-55 4HL7-A nrPDB 207 6e-54 2IM5-A nrPDB 203 1e-52 3OS4-A nrPDB 200 9e-52 1YBE-A nrPDB 179 2e-45 2F7F-A nrPDB 61 8e-10 4YUB-A nrPDB 35 0.052 3RF5-A nrPDB 30 1.5 1ZFJ-A nrPDB 29 4.0 3Q5I-A nrPDB 29 4.2 6BRH-A nrPDB 28 6.7 >1VLP-A nrPDB Length = 441 Score = 891 bits (2302), Expect = 0.0, Method: Compositional matrix adjust. Identities = 429/429 (100%), Positives = 429/429 (100%) Query: 1 MSEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYL 60 MSEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYL Sbjct: 13 MSEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYL 72 Query: 61 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL 120 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL Sbjct: 73 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL 132 Query: 121 VSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTR 180 VSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTR Sbjct: 133 VSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTR 192 Query: 181 RRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS 240 RRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS Sbjct: 193 RRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS 252 Query: 241 ISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP 300 ISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP Sbjct: 253 ISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP 312 Query: 301 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND 360 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND Sbjct: 313 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND 372 Query: 361 FRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMGDPATVKRVKEELGYTERSWS 420 FRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMGDPATVKRVKEELGYTERSWS Sbjct: 373 FRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMGDPATVKRVKEELGYTERSWS 432 Query: 421 GDNEAHRWT 429 GDNEAHRWT Sbjct: 433 GDNEAHRWT 441 >1YIR-A nrPDB Length = 408 Score = 211 bits (538), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 138/426 (32%), Positives = 226/426 (53%), Gaps = 44/426 (10%) Query: 2 SEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQ-LTFNKEAINWLKEQFSYL 60 SE ++++LLDTD YK+TM AV N+P+ V +++ R+ + L AI +EQ YL Sbjct: 9 SERIVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQEDLRLYLPAI---REQLEYL 65 Query: 61 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL 120 L ++E++ +L++ IP+L +I+++ ++ +P + IE +LK Sbjct: 66 AGLAISDEQLAFLER-IPFLAPDFIRFLGL--FRFNPR----YVQTGIENDEFFLRLK-- 116 Query: 121 VSGSWKDTILYEIPLLSLISE----AYFKFVDIDWDYENQLE-----QAEKKAETLFDNG 171 G W IL+E+PLL++ISE A + ++ E E + E AE L G Sbjct: 117 --GPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASAEEL--AG 172 Query: 172 IRFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVA 231 + ++FGTRRR S + + ++ G+ + G +GTSN+ A+K +KP+GT+A Sbjct: 173 FKMADFGTRRRFSYRVHEAVVSGLKEDFPG-------CFVGTSNVHLARKLDLKPLGTMA 225 Query: 232 HEWVMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYV 291 HEW+M + + + A+DCW+ + G+ALTD TD FL+ F ++ + Sbjct: 226 HEWLMAHQQLGPRLIDSQSAALDCWVREYRGL-LGIALTDCITTDAFLRDFDLYFAKLFD 284 Query: 292 GVRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATF 351 G+R DSGDP+ + +K HY L + +K + +SD L++ +A+ + A + + +F Sbjct: 285 GLRHDSGDPLLWAEKTIAHYLK-LGIDPLTKTLVFSDGLDLPRALKI-YRALQGRINVSF 342 Query: 352 GIGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGK-NMGDPATVKRVKE 410 GIGT+FT D P V EP+NIV+K+ NG+ KISD GK DP + +K Sbjct: 343 GIGTHFTCDL-----PGV--EPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKH 395 Query: 411 ELGYTE 416 E Sbjct: 396 VFQVAE 401 >4HL7-A nrPDB Length = 446 Score = 207 bits (528), Expect = 6e-54, Method: Compositional matrix adjust. Identities = 137/420 (32%), Positives = 225/420 (53%), Gaps = 27/420 (6%) Query: 2 SEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLG 61 S +I+SLLD D YKI M A+ +PDV+V Y+ RS + ++ ++++ ++LG Sbjct: 9 SPHIIRSLLDLDAYKINMMQAIHHFYPDVSVRYELIVRSEEDA--SGLLDAIRQEIAHLG 66 Query: 62 NLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILV 121 LRF++ +I YL Q P+L + +++ S + P+EQ+ + GK +L+I + Sbjct: 67 TLRFSDADIHYLTQHAPHLKATFLQ--SLRYFHFVPQEQVEMGIVKQGGKQ---QLRISI 121 Query: 122 SGSWKDTILYEIPLLSLISE--AYFKFVDIDWDY-----ENQLEQAEKKAETLFDNGIRF 174 GSW+DTILYE +++++SE + ++ ++ D + +L+Q + + E N Sbjct: 122 RGSWRDTILYETLVMAIVSEVRSRQRWAEVPADLPLKVLKTKLDQLKAEIERRGINNFSL 181 Query: 175 SEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEW 234 +E GTRRR S + Q ++ + + + +LGTSN FA+++ +KPIGT+AHEW Sbjct: 182 TEMGTRRRFSSQVQRDVLACLKQEI-------PQWVLGTSNYHFAREFDLKPIGTIAHEW 234 Query: 235 VMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVR 294 MG ++ + + + A++ W+ F A +A TDT D FL F ++AY GVR Sbjct: 235 FMGHQALVNER-DSQQVALERWLTAFDGMLA-IAPTDTLTIDAFLNDFNRHLANAYDGVR 292 Query: 295 QDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIG 354 DSG P + K+ HY L + +K+ +SD L+ ++A+ + +FGIG Sbjct: 293 HDSGCPFRWGDKMIAHYQQ-LGIDPTTKLFIFSDGLDFDQALELCEYFAGRVKI-SFGIG 350 Query: 355 TNFTNDFRK-KSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMG-DPATVKRVKEEL 412 T TND ++ V+ PL+IVIKL E G KISD K M DP + +K Sbjct: 351 TFLTNDLANWRNAAGVEYRPLSIVIKLAECQGRPVAKISDQPEKAMCEDPIFLANLKRRF 410 >2IM5-A nrPDB Length = 394 Score = 203 bits (517), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 138/415 (33%), Positives = 216/415 (52%), Gaps = 33/415 (7%) Query: 5 VIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLR 64 +I+S+LDTD+YK T A FP +++ +R+ Q F +E ++ + + L Sbjct: 3 IIRSILDTDLYKFTTGYAYAKLFPRAYGEFRFIDRNRQ-GFTEEFAELVRGEIRAMAALS 61 Query: 65 FTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILVSGS 124 T +E E+L++E+PYLP YI ++ ++ PEE S + +G L I G Sbjct: 62 LTRDEKEFLQRELPYLPPIYIDFLD--GFRFDPEEVT--VSIDAQGH-----LDIRAQGL 112 Query: 125 WKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRS 184 L+E P+L++ISE Y++F+ + D++ E K E + ++ FS FG RRR S Sbjct: 113 LYRVTLWETPILAVISELYYRFIGAEPDWKQVEEVTRSKGELMREHRATFSIFGMRRRFS 172 Query: 185 LKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASISED 244 L+ +D + I+K G L GTSN+ A K+G++ GT HEW+ +I Sbjct: 173 LEVEDRVTD-ILKQYAGES------LFGTSNVHLAHKHGLRVSGTHPHEWIQFHGAIY-G 224 Query: 245 YLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDPVEYT 304 Y AN AM+ WIN + + G LTDT+ TD F+++F ++ + +R DSGDP + Sbjct: 225 YKMANYVAMEDWINVYDG-DLGTVLTDTYTTDVFMRNFSKKHAMLFTSLRHDSGDPEIFI 283 Query: 305 KKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRKK 364 +K Y ++ PK K I +SDSL ++AI + A+FGIGTN TND Sbjct: 284 EKAVRRYEELRVDPKI-KYIIFSDSLTPQRAIEIQKLCAGR-IKASFGIGTNLTNDVGG- 340 Query: 365 SEPQVKSEPLNIVIKLLEV------NGNHAIKISDNLGKNMGDPATVKRVKEELG 413 EPLNIV+KL + + ++ +K+SD GK+ G+P + LG Sbjct: 341 -----GVEPLNIVMKLWKCKMTAKDDWHYCVKLSDVDGKHTGEPEEILLAMNTLG 390 >3OS4-A nrPDB Length = 407 Score = 200 bits (509), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 134/425 (31%), Positives = 217/425 (51%), Gaps = 49/425 (11%) Query: 2 SEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQL--TFNKEAINWLKEQFSY 59 + P++ SLLDTD YK+ M AVF ++ +TV ++ RS +L + E ++ Q + Sbjct: 5 ASPILTSLLDTDAYKLHMQQAVFHHYRHITVAAEFRCRSDELLGVYADE----IRHQVTL 60 Query: 60 LGNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKI 119 +G L T +E YL +P+ Y+ ++ +K EQ+S + KL I Sbjct: 61 MGQLALTSDEFIYLS-SLPFFQDDYLHWLRDFRFK---PEQVSVAVHD-------GKLDI 109 Query: 120 LVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGI------- 172 ++G W + I++E+PLL++ISE + + ++Q K E N + Sbjct: 110 RIAGLWCEVIMWEVPLLAVISEIVHRRRSTQVTTDQAVQQLRTKLEQF--NALSADIDIT 167 Query: 173 --RFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTV 230 + +FGTRRR S + Q ++ + L+GTSN A+ + P+GT Sbjct: 168 HFKLMDFGTRRRFSREIQHTVVSTLKDEF--------PYLVGTSNYDLARTLALAPVGTQ 219 Query: 231 AHEWVMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAY 290 AHEW IS ++ + A+ W++ + G+ALTD D FL+ F +++ Y Sbjct: 220 AHEWFQAHQQISPTLANSQRVALQVWLDEY-PNQLGIALTDCITMDAFLRDFDLAFANRY 278 Query: 291 VGVRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAI-TYSHAAKENGMLA 349 G+R DSGDP+E+ +K HY + L + K++ +SD+L++EKA+ Y H + ++ Sbjct: 279 QGLRHDSGDPIEWGEKAIAHY-EKLGIDPMKKVLVFSDNLDLEKALFLYRHFYQRIKLV- 336 Query: 350 TFGIGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMG-DPATVKRV 408 FGIGT T D P VK PLNIVIKL+E N K+SD+ GK + DPA V ++ Sbjct: 337 -FGIGTRLTCDI-----PDVK--PLNIVIKLVECNDKPVAKLSDSPGKTICQDPAFVDQL 388 Query: 409 KEELG 413 ++ Sbjct: 389 RKAFA 393 >1YBE-A nrPDB Length = 449 Score = 179 bits (454), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 134/424 (31%), Positives = 218/424 (51%), Gaps = 43/424 (10%) Query: 3 EPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINW-LKEQFSYLG 61 +P+++SL+DTD YK+ M ++ +P+V T+ NR+ + +E L+EQ + Sbjct: 25 DPIVRSLIDTDFYKLLMLQMIWKLYPEVDATFSLINRTKTVRLAEEIDEMELREQLDHAR 84 Query: 62 NLRFTEEEIEYLKQEIPYLPSA-----YIKYISSSNYKLHPEEQISFTSEEIEGKPTHYK 116 LR +++E +L Y S ++ ++SS Y+L PE E+ + Y+ Sbjct: 85 TLRLSKKENIWLAGNTFYGRSQIFEPEFLSWLSS--YQL-PEY-------ELFKRDGQYE 134 Query: 117 LKILVSGSWKDTILYEIPLLSLISEAYFK-------FVDIDWDYENQLEQAEKKAETLFD 169 L G W DT L+EIP LS+I+E + + +D Y + +K E L + Sbjct: 135 LNF--HGRWMDTTLWEIPALSIINELRSRSAMRSLGYFTLDVLYARAKAKMWEKVERLRE 192 Query: 170 -NGIRFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIG 228 G+R S+FGTRRR S Q ++ + + + GTSN+L A ++ +G Sbjct: 193 LPGLRISDFGTRRRHSFLWQRWCVEALKEGIG-------PAFTGTSNVLLAMDSDLEAVG 245 Query: 229 TVAHEWVMGVASIS---EDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPP 285 T AHE M VA+++ E+ A + W +G N + L D FGT FL++ P Sbjct: 246 TNAHELPMVVAALAQTNEELAAAPYQVLKDWNRLYGG-NLLIVLPDAFGTAAFLRN-APE 303 Query: 286 YSDAYVGVRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAI-TYSHAAKE 344 + + G R DS P+E +KI + + + P+ +K++ +SD L+V+ + TY H E Sbjct: 304 WVADWTGFRPDSAPPIEGGEKIIEWWRKMGRDPR-TKMLIFSDGLDVDAIVDTYRHF--E 360 Query: 345 NGMLATFGIGTNFTNDFRKKSEPQVKS-EPLNIVIKLLEVNGNHAIKISDNLGKNMGDPA 403 + +FG GTN TNDF + + S +P++IV K+ + NG A+K+SDN K GDPA Sbjct: 361 GRVRMSFGWGTNLTNDFAGCAPKTIASLKPISIVCKVSDANGRPAVKLSDNPQKATGDPA 420 Query: 404 TVKR 407 V+R Sbjct: 421 EVER 424 >2F7F-A nrPDB Length = 494 Score = 61.2 bits (147), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 90/402 (22%), Positives = 156/402 (38%), Gaps = 71/402 (17%) Query: 10 LDTDMYKITMHAAVF-TNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEE 68 L TDMY+I M + D+ ++ R L+ +YL NL FTE Sbjct: 12 LHTDMYQINMMQTYWELGRADLHAVFECYFREMPFNHGYAIFAGLERLVNYLENLTFTES 71 Query: 69 EIEYLKQEIPYLPSAYIKYISSSNYKLHP----EEQISFTSEEIEGKPTHYKLKILVSGS 124 +I YL+ E+ P ++ Y+++ +K E + F +E + I + G Sbjct: 72 DIAYLR-EVEEYPEDFLTYLANFEFKCTVRSALEGDLVFNNEPL----------IQIEGP 120 Query: 125 WKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRS 184 L E LL+++ +++ + + +++ + EFGTRR + Sbjct: 121 LAQCQLVETALLNMV------------NFQTLIATKAARIKSVIGDD-PLLEFGTRRAQE 167 Query: 185 LKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASISED 244 L D + G A G D TSN+ K +G+ GT AH V + E Sbjct: 168 L---DAAIWGTRAAYIGGAD-------ATSNVRAGKIFGIPVSGTHAHSLVQSYGNDYEA 217 Query: 245 YLHANKNAMDC--WINTFGAKNAGL--ALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP 300 ++ K DC ++T+ AG+ A+ D + ++GVR DSGD Sbjct: 218 FMAYAKTHRDCVFLVDTYDTLKAGVPSAIRVAREMGDKIN---------FLGVRIDSGDM 268 Query: 301 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND 360 +K++ L F++ Y+ + E I + + + +G+GT Sbjct: 269 AYISKRVREQ----LDEAGFTEAKIYASNDLDENTIL--NLKMQKSKIDVWGVGTKLITA 322 Query: 361 FRKKSEPQVKSEPLNIVIKLLEVNGNHA-----IKISDNLGK 397 + + + L V KL+ + G IK+S N K Sbjct: 323 YDQPA--------LGAVFKLVSIEGEDGQMKDTIKLSSNAEK 356 >4YUB-A nrPDB Length = 538 Score = 35.4 bits (80), Expect = 0.052, Method: Compositional matrix adjust. Identities = 88/400 (22%), Positives = 147/400 (36%), Gaps = 106/400 (26%) Query: 53 LKEQFSYLGNLRFTEEEIEYLKQEIPYLP---SAYIKYI-----SSSNYKLHPEEQISFT 104 L++ +L R + ++++L +P P A+ +++ S + PE ++F Sbjct: 60 LRDCVRFLRAFRLRDADVQFLASVLP--PDTDPAFFEHLRALDCSEVTVRALPEGSLAFP 117 Query: 105 SEEIEGKPTHYKLKILVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKA 164 G P + VSG L E PLL L+S Y V + + EK Sbjct: 118 -----GVPL-----LQVSGPLLVVQLLETPLLCLVS--YASLVATNAARLRLIAGPEK-- 163 Query: 165 ETLFDNGIRFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLG---TSNILFAKK 221 R E G RR QG + + S L G +SN+L + Sbjct: 164 --------RLLEMGLRR----------AQGPDGGLTAS---TYSYLGGFDSSSNVLAGQL 202 Query: 222 YGVKPIGTVAHEWVMGVAS--ISEDYLHANKNA----------MDCWINTF--------- 260 GV GT+AH +V + + D + A W+ Sbjct: 203 RGVPVAGTLAHSFVTSFSGSEVPPDPMLAPAAGEGPGVDLAAKAQVWLEQVCAHLGLGVQ 262 Query: 261 ----GAKNAGLA-----------LTDTF-----GTDDFLKSFRPPYSDAY--VGVRQDSG 298 G + A +A L DT+ G +FL Y VGVR DSG Sbjct: 263 EPHPGERAAFVAYALAFPRAFQGLLDTYSVWRSGLPNFLAVALALGELGYRAVGVRLDSG 322 Query: 299 DPVEYTKKISHHYHDV---LKLPKF-SKIICYSDSLNVEKAITYSHAAKENGMLATFGIG 354 D ++ ++I + ++P S +I S++++ E + A+E + GIG Sbjct: 323 DLLQQAQEIRKVFRAAAAQFQVPWLESVLIVVSNNIDEE---ALARLAQEGSEVNVIGIG 379 Query: 355 TNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDN 394 T+ ++ S L V KL+ V G +K++++ Sbjct: 380 TSVVTCPQQPS--------LGGVYKLVAVGGQPRMKLTED 411 >3RF5-A nrPDB Length = 116 Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 14/30 (46%), Positives = 18/30 (60%) Query: 299 DPVEYTKKISHHYHDVLKLPKFSKIICYSD 328 D + +T+KI+ D LKLPK II Y D Sbjct: 71 DNIRHTQKITQFCQDTLKLPKDKVIITYFD 100 >1ZFJ-A nrPDB Length = 491 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 13/110 (11%) Query: 278 FLKSFRPPYSDAYVG---VRQDSGDPVEYTKKISHHYHDVLKLP------KFSKIICYSD 328 F+ + P S+ V G +E ++I H H + KLP + S +I D Sbjct: 146 FISDYNAPISEHMTSEHLVTAAVGTDLETAERILHE-HRIEKLPLVDNSGRLSGLITIKD 204 Query: 329 SLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRKKSEPQVKSEPLNIVI 378 +EK I + HAAK+ T+D +++E ++ IVI Sbjct: 205 ---IEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEAGADAIVI 251 >3Q5I-A nrPDB Length = 504 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 2/61 (3%) Query: 48 EAINWLKEQFSYLGNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEE 107 E N L+ + LG L+ EEE++ + +E+ + + YI+Y S + ++QI F+ E Sbjct: 379 EGYNVLRNFKNELGELKNVEEEVDNILKEVDFDKNGYIEY--SEFISVCMDKQILFSEER 436 Query: 108 I 108 + Sbjct: 437 L 437 >6BRH-A nrPDB Length = 672 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 14/21 (66%) Query: 92 NYKLHPEEQISFTSEEIEGKP 112 NY L PEE I+F E+I G P Sbjct: 302 NYGLVPEEDITFIKEQIMGPP 322 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1VLP-A nrPDB 605 e-173 4HL7-A nrPDB 474 e-134 1YIR-A nrPDB 459 e-129 3OS4-A nrPDB 449 e-126 2IM5-A nrPDB 441 e-124 1YBE-A nrPDB 425 e-119 2F7F-A nrPDB 317 7e-87 Sequences not found previously or not previously below threshold: 4YUB-A nrPDB 123 2e-28 1YTE-A nrPDB 61 1e-09 2I14-A nrPDB 56 4e-08 2C1U-A nrPDB 29 3.7 3GOD-A nrPDB 29 5.7 1PZV-A nrPDB 28 6.7 2XKJ-E nrPDB 28 8.9 >1VLP-A nrPDB Length = 441 Score = 605 bits (1560), Expect = e-173, Method: Composition-based stats. Identities = 429/429 (100%), Positives = 429/429 (100%) Query: 1 MSEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYL 60 MSEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYL Sbjct: 13 MSEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYL 72 Query: 61 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL 120 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL Sbjct: 73 GNLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKIL 132 Query: 121 VSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTR 180 VSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTR Sbjct: 133 VSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTR 192 Query: 181 RRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS 240 RRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS Sbjct: 193 RRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS 252 Query: 241 ISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP 300 ISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP Sbjct: 253 ISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP 312 Query: 301 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND 360 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND Sbjct: 313 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND 372 Query: 361 FRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMGDPATVKRVKEELGYTERSWS 420 FRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMGDPATVKRVKEELGYTERSWS Sbjct: 373 FRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMGDPATVKRVKEELGYTERSWS 432 Query: 421 GDNEAHRWT 429 GDNEAHRWT Sbjct: 433 GDNEAHRWT 441 >4HL7-A nrPDB Length = 446 Score = 474 bits (1219), Expect = e-134, Method: Composition-based stats. Identities = 136/422 (32%), Positives = 224/422 (53%), Gaps = 27/422 (6%) Query: 2 SEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLG 61 S +I+SLLD D YKI M A+ +PDV+V Y+ RS + ++ ++++ ++LG Sbjct: 9 SPHIIRSLLDLDAYKINMMQAIHHFYPDVSVRYELIVRSEED--ASGLLDAIRQEIAHLG 66 Query: 62 NLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILV 121 LRF++ +I YL Q P+L + +++ S + P+EQ+ + GK +L+I + Sbjct: 67 TLRFSDADIHYLTQHAPHLKATFLQ--SLRYFHFVPQEQVEMGIVKQGGKQ---QLRISI 121 Query: 122 SGSWKDTILYEIPLLSLISE--AYFKFVDIDWDY-----ENQLEQAEKKAETLFDNGIRF 174 GSW+DTILYE +++++SE + ++ ++ D + +L+Q + + E N Sbjct: 122 RGSWRDTILYETLVMAIVSEVRSRQRWAEVPADLPLKVLKTKLDQLKAEIERRGINNFSL 181 Query: 175 SEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEW 234 +E GTRRR S + Q ++ + + + +LGTSN FA+++ +KPIGT+AHEW Sbjct: 182 TEMGTRRRFSSQVQRDVLACLKQEI-------PQWVLGTSNYHFAREFDLKPIGTIAHEW 234 Query: 235 VMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVR 294 MG ++ + + + A++ W+ F +A TDT D FL F ++AY GVR Sbjct: 235 FMGHQALVNER-DSQQVALERWLTAFDGM-LAIAPTDTLTIDAFLNDFNRHLANAYDGVR 292 Query: 295 QDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIG 354 DSG P + K+ HY L + +K+ +SD L+ ++A+ + +FGIG Sbjct: 293 HDSGCPFRWGDKMIAHYQQ-LGIDPTTKLFIFSDGLDFDQALELCEYFAGRVKI-SFGIG 350 Query: 355 TNFTNDFRK-KSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMG-DPATVKRVKEEL 412 T TND ++ V+ PL+IVIKL E G KISD K M DP + +K Sbjct: 351 TFLTNDLANWRNAAGVEYRPLSIVIKLAECQGRPVAKISDQPEKAMCEDPIFLANLKRRF 410 Query: 413 GY 414 Sbjct: 411 NI 412 >1YIR-A nrPDB Length = 408 Score = 459 bits (1181), Expect = e-129, Method: Composition-based stats. Identities = 133/425 (31%), Positives = 223/425 (52%), Gaps = 42/425 (9%) Query: 2 SEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLG 61 SE ++++LLDTD YK+TM AV N+P+ V +++ R+ + + ++EQ YL Sbjct: 9 SERIVQNLLDTDFYKLTMMQAVLHNYPNAEVEWEFRCRNQEDLRLY--LPAIREQLEYLA 66 Query: 62 NLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILV 121 L ++E++ +L++ IP+L +I+++ ++ +P + IE +LK Sbjct: 67 GLAISDEQLAFLER-IPFLAPDFIRFLGL--FRFNPR----YVQTGIENDEFFLRLK--- 116 Query: 122 SGSWKDTILYEIPLLSLISE----AYFKFVDIDWDYENQLE-----QAEKKAETLFDNGI 172 G W IL+E+PLL++ISE A + ++ E E + E AE L G Sbjct: 117 -GPWLHVILFEVPLLAMISEVRNRARYPAATVEQARERLQEKFDWLRREASAEEL--AGF 173 Query: 173 RFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAH 232 + ++FGTRRR S + + ++ G+ + G +GTSN+ A+K +KP+GT+AH Sbjct: 174 KMADFGTRRRFSYRVHEAVVSGLKEDFPG-------CFVGTSNVHLARKLDLKPLGTMAH 226 Query: 233 EWVMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVG 292 EW+M + + + A+DCW+ + G+ALTD TD FL+ F ++ + G Sbjct: 227 EWLMAHQQLGPRLIDSQSAALDCWVREYRGL-LGIALTDCITTDAFLRDFDLYFAKLFDG 285 Query: 293 VRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFG 352 +R DSGDP+ + +K HY L + +K + +SD L++ +A+ + A + + +FG Sbjct: 286 LRHDSGDPLLWAEKTIAHYLK-LGIDPLTKTLVFSDGLDLPRALKI-YRALQGRINVSFG 343 Query: 353 IGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKN-MGDPATVKRVKEE 411 IGT+FT D EP+NIV+K+ NG+ KISD GK DP + +K Sbjct: 344 IGTHFTCDLPG-------VEPMNIVVKMSACNGHPVAKISDTPGKAQCRDPDFIHYLKHV 396 Query: 412 LGYTE 416 E Sbjct: 397 FQVAE 401 >3OS4-A nrPDB Length = 407 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 132/421 (31%), Positives = 212/421 (50%), Gaps = 41/421 (9%) Query: 2 SEPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLG 61 + P++ SLLDTD YK+ M AVF ++ +TV ++ RS +L + ++ Q + +G Sbjct: 5 ASPILTSLLDTDAYKLHMQQAVFHHYRHITVAAEFRCRSDELLGVYA--DEIRHQVTLMG 62 Query: 62 NLRFTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILV 121 L T +E YL +P+ Y+ ++ +K EQ+S + KL I + Sbjct: 63 QLALTSDEFIYLS-SLPFFQDDYLHWLRDFRFK---PEQVSVAVHD-------GKLDIRI 111 Query: 122 SGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLF-------DNGIRF 174 +G W + I++E+PLL++ISE + + ++Q K E + Sbjct: 112 AGLWCEVIMWEVPLLAVISEIVHRRRSTQVTTDQAVQQLRTKLEQFNALSADIDITHFKL 171 Query: 175 SEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEW 234 +FGTRRR S + Q ++ + L+GTSN A+ + P+GT AHEW Sbjct: 172 MDFGTRRRFSREIQHTVVSTLKDEF--------PYLVGTSNYDLARTLALAPVGTQAHEW 223 Query: 235 VMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVR 294 IS ++ + A+ W++ + G+ALTD D FL+ F +++ Y G+R Sbjct: 224 FQAHQQISPTLANSQRVALQVWLDEY-PNQLGIALTDCITMDAFLRDFDLAFANRYQGLR 282 Query: 295 QDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAI-TYSHAAKENGMLATFGI 353 DSGDP+E+ +K HY L + K++ +SD+L++EKA+ Y H + + FGI Sbjct: 283 HDSGDPIEWGEKAIAHYEK-LGIDPMKKVLVFSDNLDLEKALFLYRHFYQ--RIKLVFGI 339 Query: 354 GTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIKISDNLGKNMG-DPATVKRVKEEL 412 GT T D P VK PLNIVIKL+E N K+SD+ GK + DPA V ++++ Sbjct: 340 GTRLTCDI-----PDVK--PLNIVIKLVECNDKPVAKLSDSPGKTICQDPAFVDQLRKAF 392 Query: 413 G 413 Sbjct: 393 A 393 >2IM5-A nrPDB Length = 394 Score = 441 bits (1135), Expect = e-124, Method: Composition-based stats. Identities = 138/419 (32%), Positives = 217/419 (51%), Gaps = 33/419 (7%) Query: 5 VIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLR 64 +I+S+LDTD+YK T A FP +++ +R+ Q F +E ++ + + L Sbjct: 3 IIRSILDTDLYKFTTGYAYAKLFPRAYGEFRFIDRNRQ-GFTEEFAELVRGEIRAMAALS 61 Query: 65 FTEEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILVSGS 124 T +E E+L++E+PYLP YI ++ ++ PEE S + +G L I G Sbjct: 62 LTRDEKEFLQRELPYLPPIYIDFLD--GFRFDPEEVT--VSIDAQGH-----LDIRAQGL 112 Query: 125 WKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRS 184 L+E P+L++ISE Y++F+ + D++ E K E + ++ FS FG RRR S Sbjct: 113 LYRVTLWETPILAVISELYYRFIGAEPDWKQVEEVTRSKGELMREHRATFSIFGMRRRFS 172 Query: 185 LKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASISED 244 L+ +D + I+K G L GTSN+ A K+G++ GT HEW+ +I Sbjct: 173 LEVEDRVTD-ILKQYAGES------LFGTSNVHLAHKHGLRVSGTHPHEWIQFHGAIY-G 224 Query: 245 YLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDPVEYT 304 Y AN AM+ WIN + + G LTDT+ TD F+++F ++ + +R DSGDP + Sbjct: 225 YKMANYVAMEDWINVYDG-DLGTVLTDTYTTDVFMRNFSKKHAMLFTSLRHDSGDPEIFI 283 Query: 305 KKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRKK 364 +K Y ++ PK K I +SDSL ++AI + A+FGIGTN TND Sbjct: 284 EKAVRRYEELRVDPKI-KYIIFSDSLTPQRAIEIQKLCAGR-IKASFGIGTNLTNDVGG- 340 Query: 365 SEPQVKSEPLNIVIKLLEV------NGNHAIKISDNLGKNMGDPATVKRVKEELGYTER 417 EPLNIV+KL + + ++ +K+SD GK+ G+P + LG + Sbjct: 341 -----GVEPLNIVMKLWKCKMTAKDDWHYCVKLSDVDGKHTGEPEEILLAMNTLGIKPK 394 >1YBE-A nrPDB Length = 449 Score = 425 bits (1093), Expect = e-119, Method: Composition-based stats. Identities = 132/430 (30%), Positives = 216/430 (50%), Gaps = 43/430 (10%) Query: 3 EPVIKSLLDTDMYKITMHAAVFTNFPDVTVTYKYTNRSSQLTFNKEAINW-LKEQFSYLG 61 +P+++SL+DTD YK+ M ++ +P+V T+ NR+ + +E L+EQ + Sbjct: 25 DPIVRSLIDTDFYKLLMLQMIWKLYPEVDATFSLINRTKTVRLAEEIDEMELREQLDHAR 84 Query: 62 NLRFTEEEIEYLKQEIPYLP-----SAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYK 116 LR +++E +L Y ++ ++SS PE E+ + Y+ Sbjct: 85 TLRLSKKENIWLAGNTFYGRSQIFEPEFLSWLSSYQL---PEY-------ELFKRDGQYE 134 Query: 117 LKILVSGSWKDTILYEIPLLSLISEAYFK-------FVDIDWDYENQLEQAEKKAETLFD 169 L G W DT L+EIP LS+I+E + + +D Y + +K E L + Sbjct: 135 LNF--HGRWMDTTLWEIPALSIINELRSRSAMRSLGYFTLDVLYARAKAKMWEKVERLRE 192 Query: 170 -NGIRFSEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIG 228 G+R S+FGTRRR S Q ++ + + + GTSN+L A ++ +G Sbjct: 193 LPGLRISDFGTRRRHSFLWQRWCVEALKEGIG-------PAFTGTSNVLLAMDSDLEAVG 245 Query: 229 TVAHEWVMGVASIS---EDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPP 285 T AHE M VA+++ E+ A + W +G N + L D FGT FL++ P Sbjct: 246 TNAHELPMVVAALAQTNEELAAAPYQVLKDWNRLYGG-NLLIVLPDAFGTAAFLRN-APE 303 Query: 286 YSDAYVGVRQDSGDPVEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAI-TYSHAAKE 344 + + G R DS P+E +KI + + + P+ +K++ +SD L+V+ + TY H E Sbjct: 304 WVADWTGFRPDSAPPIEGGEKIIEWWRKMGRDPR-TKMLIFSDGLDVDAIVDTYRHF--E 360 Query: 345 NGMLATFGIGTNFTNDFRKKSEPQVKS-EPLNIVIKLLEVNGNHAIKISDNLGKNMGDPA 403 + +FG GTN TNDF + + S +P++IV K+ + NG A+K+SDN K GDPA Sbjct: 361 GRVRMSFGWGTNLTNDFAGCAPKTIASLKPISIVCKVSDANGRPAVKLSDNPQKATGDPA 420 Query: 404 TVKRVKEELG 413 V+R + G Sbjct: 421 EVERYLKFFG 430 >2F7F-A nrPDB Length = 494 Score = 317 bits (811), Expect = 7e-87, Method: Composition-based stats. Identities = 90/404 (22%), Positives = 156/404 (38%), Gaps = 71/404 (17%) Query: 10 LDTDMYKITMHAAVF-TNFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEE 68 L TDMY+I M + D+ ++ R L+ +YL NL FTE Sbjct: 12 LHTDMYQINMMQTYWELGRADLHAVFECYFREMPFNHGYAIFAGLERLVNYLENLTFTES 71 Query: 69 EIEYLKQEIPYLPSAYIKYISSSNYKLHP----EEQISFTSEEIEGKPTHYKLKILVSGS 124 +I YL +E+ P ++ Y+++ +K E + F +E + I + G Sbjct: 72 DIAYL-REVEEYPEDFLTYLANFEFKCTVRSALEGDLVFNNEPL----------IQIEGP 120 Query: 125 WKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRS 184 L E LL+++ +++ + + +++ + EFGTRR + Sbjct: 121 LAQCQLVETALLNMV------------NFQTLIATKAARIKSVIGDD-PLLEFGTRRAQE 167 Query: 185 LKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVASISED 244 L D + G A G D TSN+ K +G+ GT AH V + E Sbjct: 168 L---DAAIWGTRAAYIGGAD-------ATSNVRAGKIFGIPVSGTHAHSLVQSYGNDYEA 217 Query: 245 YLHANKNAMDC--WINTFGAKNAGL--ALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDP 300 ++ K DC ++T+ AG+ A+ D + ++GVR DSGD Sbjct: 218 FMAYAKTHRDCVFLVDTYDTLKAGVPSAIRVAREMGDKIN---------FLGVRIDSGDM 268 Query: 301 VEYTKKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTND 360 +K++ L F++ Y+ + E I + + + +G+GT Sbjct: 269 AYISKRVREQ----LDEAGFTEAKIYASNDLDENTIL--NLKMQKSKIDVWGVGTKLITA 322 Query: 361 FRKKSEPQVKSEPLNIVIKLLEVNGNHA-----IKISDNLGKNM 399 + + + L V KL+ + G IK+S N K Sbjct: 323 YDQPA--------LGAVFKLVSIEGEDGQMKDTIKLSSNAEKVT 358 >4YUB-A nrPDB Length = 538 Score = 123 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 77/444 (17%), Positives = 148/444 (33%), Gaps = 97/444 (21%) Query: 10 LDTDMYKITMHAAVFT-NFPDVTVTYKYTNRSSQLTFNKEAINWLKEQFSYLGNLRFTEE 68 L TD+Y+ TM + ++ R L++ +L R + Sbjct: 16 LLTDLYQATMALGYWRAGRARDAAEFELFFRRCPFGGAFALAAGLRDCVRFLRAFRLRDA 75 Query: 69 EIEYLKQEIP-YLPSAYIKYI-----SSSNYKLHPEEQISFTSEEIEGKPTHYKLKILVS 122 ++++L +P A+ +++ S + PE ++F + + VS Sbjct: 76 DVQFLASVLPPDTDPAFFEHLRALDCSEVTVRALPEGSLAFPGVPL----------LQVS 125 Query: 123 GSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRR 182 G L E PLL L+S Y + + + + R E G RR Sbjct: 126 GPLLVVQLLETPLLCLVS------------YASLVATNAARLRLIAGPEKRLLEMGLRRA 173 Query: 183 RSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVMGVAS-- 240 + D + + G D +SN+L + GV GT+AH +V + Sbjct: 174 QG---PDGGLTASTYSYLGGFDS-------SSNVLAGQLRGVPVAGTLAHSFVTSFSGSE 223 Query: 241 ------ISEDYLHANKNAM----DCWINTFGA-KNAGLALTDTFGTDDFLKSFRPPYSDA 289 ++ + W+ A G+ F+ ++ + A Sbjct: 224 VPPDPMLAPAAGEGPGVDLAAKAQVWLEQVCAHLGLGVQEPHPGERAAFV-AYALAFPRA 282 Query: 290 YVG-------------------------------VRQDSGDPVEYTKKISHHYHD---VL 315 + G VR DSGD ++ ++I + Sbjct: 283 FQGLLDTYSVWRSGLPNFLAVALALGELGYRAVGVRLDSGDLLQQAQEIRKVFRAAAAQF 342 Query: 316 KLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGTNFTNDFRKKSEPQVKSEPLN 375 ++P ++ + E+A+ + A+E + GIGT+ ++ S L Sbjct: 343 QVPWLESVLIVVSNNIDEEAL--ARLAQEGSEVNVIGIGTSVVTCPQQPS--------LG 392 Query: 376 IVIKLLEVNGNHAIKISDNLGKNM 399 V KL+ V G +K++++ K Sbjct: 393 GVYKLVAVGGQPRMKLTEDPEKQT 416 >1YTE-A nrPDB Length = 398 Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 52/275 (18%), Positives = 83/275 (30%), Gaps = 53/275 (19%) Query: 119 ILVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFG 178 I V G + D +YE +L I +A + + K L F FG Sbjct: 99 IRVEGRYCDFGMYETAILGFICQA------------SGISTKASKV-RLAAGDSPFFSFG 145 Query: 179 TRRRRSLKAQDLIMQGI--MKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEWVM 236 RR + + A G D G S IL AK P+GT+ H Sbjct: 146 IRRMHP------AISPMIDRSAYIGGAD-------GVSGILGAKLIDQDPVGTMPHAL-- 190 Query: 237 GVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSFRPPYSDAYVGVRQD 296 + ++ A + + L DT+ + F D +R D Sbjct: 191 -------SIMLGDEEAWKLTLENTKNGQKSVLLIDTYMDEKFAAIKIAEMFDKVDYIRLD 243 Query: 297 SGDPVEYT-KKISHHYHDVLKLPKFSKIICYSDSLNVEKAITYSHAAKENGMLATFGIGT 355 + + + L L S I E + FG+GT Sbjct: 244 TPSSRRGNFEALIREVRWELALRGRSDIKIMVSGGLDENTVK----KLREAGAEAFGVGT 299 Query: 356 NFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIK 390 + ++ +P + + ++EVNG K Sbjct: 300 SISSA-----------KPFDFAMDIVEVNGKPETK 323 >2I14-A nrPDB Length = 395 Score = 55.6 bits (132), Expect = 4e-08, Method: Composition-based stats. Identities = 52/280 (18%), Positives = 98/280 (35%), Gaps = 54/280 (19%) Query: 115 YKLKILVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRF 174 Y+ + + G + D +YE LL ++S+A + K + Sbjct: 91 YEPVLQIEGDYADFGIYETALLGMLSQA------SGIATAALRIKIAAKFK-------PV 137 Query: 175 SEFGTRRRRSLKAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPIGTVAHEW 234 FG R A ++ A G D G S +L A+ G K +GT+ H Sbjct: 138 YSFGIRHMHPAIAP--MID--RAAFIGGCD-------GVSGVLGAEMMGEKAVGTMPHAL 186 Query: 235 VMGVASISEDYLHANKNAMDCWINTFGAKNAGLALTDTFGTDDFLKSF--RPPYSDAYVG 292 ++ V + + + ++ + +AL DTF D+ +++ Sbjct: 187 IITVGDQVKAWKYFDEVIEEEVPR--------IALVDTF-YDEKVEAVMAAEALGKKLFA 237 Query: 293 VRQDSGDPVEYT-KKISHHYHDVLKLPKFSKIICY-SDSLNVEKAITYSHAAKENGMLAT 350 VR D+ +KI LK+ + + + S L+ EK ++ Sbjct: 238 VRLDTPSSRRGNFRKIIEEVRWELKVRGYDWVKIFVSGGLDEEKIKEIVD------VVDA 291 Query: 351 FGIGTNFTNDFRKKSEPQVKSEPLNIVIKLLEVNGNHAIK 390 FG+G ++P++ + ++EV G K Sbjct: 292 FGVG-----------GAIASAKPVDFALDIVEVEGKPIAK 320 >2C1U-A nrPDB Length = 338 Score = 29.0 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 22/114 (19%), Positives = 38/114 (33%), Gaps = 13/114 (11%) Query: 215 NILFAKKYGVKPIGTVAHEWVMGVASISEDYLHANKNAMDCWI--------NTFGAKNAG 266 N+ G+ + H W G + + L+A NA W G AG Sbjct: 70 NVGLGGVDGLPTS--IGHGWQKGPRN-APTMLNAIFNAAQFWDGRAADLAEQAKGPVQAG 126 Query: 267 LALTDTFGTDDFLKSFRPPYSDAYVGVRQDSGDPVEYTK--KISHHYHDVLKLP 318 + +++T + P Y +A+ + DPV + + L P Sbjct: 127 VEMSNTPDQVVKTINSMPEYVEAFKAAFPEEADPVTFDNFAAAIEQFEATLITP 180 >3GOD-A nrPDB Length = 328 Score = 28.6 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 19/162 (11%), Positives = 58/162 (35%), Gaps = 7/162 (4%) Query: 67 EEEIEYLKQEIPYLPSAYIKYISSSNYKLHPEEQISFTSEEIEGKPTHYKLKILVSGSWK 126 + E+ +L + Y P+ Y++ + E+++ + + L + Sbjct: 102 DVEVSWLTPQSEYRPTEYLQ--RWVGFWFDEEKRLVAARHFQRARLERIRHSWLEDRVLR 159 Query: 127 DTIL-YEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAETLFDNGIRFSEFGTRRRRSL 185 D + L++ E + ++ ++E+ L + + ++ L + + TR + Sbjct: 160 DAGFAVDATALAVAVEDSARALEQAPNHEHLLTEEARLSKRL----FKLAAQATRYGEFV 215 Query: 186 KAQDLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKPI 227 +A+ + + L T+ + +G+ + Sbjct: 216 RAKRGSGGDPANRFLDHGNYLAYGLAATATWVLGIPHGLAVL 257 >1PZV-A nrPDB Length = 164 Score = 28.3 bits (61), Expect = 6.7, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 15/46 (32%) Query: 120 LVSGSWKDTILYEIPLLSLISEAYFKFVDIDWDYENQLEQAEKKAE 165 W E LLS+IS + + + Q E AE Sbjct: 104 RPEERWLPVHTVETILLSVISMLTDPNFESPANVDAAKMQRENYAE 149 >2XKJ-E nrPDB Length = 767 Score = 27.9 bits (60), Expect = 8.9, Method: Composition-based stats. Identities = 13/98 (13%), Positives = 34/98 (34%), Gaps = 9/98 (9%) Query: 135 LLSLISEAYFKFVDIDWDY------ENQLEQAEKKAETLFDNGIRFSEFGTRRRRSLKAQ 188 L++ + ++ ++ ++ +A+ + + SE G + + + Q Sbjct: 356 LMAQPFSYRYPLIEGQGNWGSPDDPKSFAAMRYTEAKLSAYSELLLSELG---QGTSEWQ 412 Query: 189 DLIMQGIMKAVNGNPDRNKSLLLGTSNILFAKKYGVKP 226 D + + + LL GT+ I + P Sbjct: 413 DNFDGSLKEPITLPARVPNILLNGTTGIAVGMATDIPP 450 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.120 0.299 Lambda K H 0.267 0.0371 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,625,504 Number of Sequences: 36641 Number of extensions: 548959 Number of successful extensions: 1972 Number of sequences better than 10.0: 18 Number of HSP's better than 10.0 without gapping: 20 Number of HSP's successfully gapped in prelim test: 16 Number of HSP's that attempted gapping in prelim test: 1854 Number of HSP's gapped (non-prelim): 37 length of query: 429 length of database: 10,336,785 effective HSP length: 100 effective length of query: 329 effective length of database: 6,672,685 effective search space: 2195313365 effective search space used: 2195313365 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 60 (27.9 bits)