BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P39099 (455 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4A8B-A nrPDB 841 0.0 3STJ-A nrPDB 664 0.0 3MH6-A nrPDB 505 e-143 3STI-A nrPDB 471 e-133 3PV2-A nrPDB 309 1e-84 4YNN-A nrPDB 300 6e-82 3PV4-A nrPDB 285 3e-77 4YO1-A nrPDB 283 2e-76 5Y2D-A nrPDB 248 3e-66 5Y28-A nrPDB 233 1e-61 5JD8-A nrPDB 212 2e-55 3GCO-A nrPDB 209 3e-54 5T69-A nrPDB 187 1e-47 3QO6-A nrPDB 172 3e-43 6IEO-A nrPDB 163 1e-40 4IC6-A nrPDB 162 2e-40 1L1J-A nrPDB 161 5e-40 2QF3-A nrPDB 159 2e-39 4RI0-A nrPDB 158 5e-39 3NUM-A nrPDB 156 1e-38 2R3U-A nrPDB 155 3e-38 2Z9I-A nrPDB 151 5e-37 3TJO-A nrPDB 134 8e-32 5M3O-A nrPDB 131 5e-31 4IC5-A nrPDB 113 2e-25 4FLN-A nrPDB 73 2e-13 5ILB-A nrPDB 72 7e-13 5HM9-A nrPDB 62 4e-10 5JYK-A nrPDB 60 1e-09 3LT3-A nrPDB 52 4e-07 5ILA-A nrPDB 51 9e-07 2KL1-A nrPDB 43 3e-04 5C2Z-A nrPDB 39 0.006 1DUE-A nrPDB 38 0.008 2HII-A nrPDB 36 0.038 5MM8-A nrPDB 35 0.094 2WV5-A nrPDB 34 0.15 2DLS-A nrPDB 33 0.31 5E6P-B nrPDB 33 0.32 2AS9-A nrPDB 32 0.45 5A2P-A nrPDB 32 0.47 5G1D-A nrPDB 32 0.53 2KJP-A nrPDB 32 0.55 4O06-A nrPDB 32 0.55 4JCN-A nrPDB 32 0.59 2KBS-A nrPDB 32 0.67 3K50-A nrPDB 32 0.72 1X5N-A nrPDB 31 0.88 3MN1-A nrPDB 31 1.2 2PKT-A nrPDB 31 1.2 4XZY-A nrPDB 30 1.6 4QL6-A nrPDB 30 1.9 2V90-A nrPDB 30 2.0 1AK5-A nrPDB 30 2.1 3QDO-A nrPDB 30 2.2 3I1E-A nrPDB 30 2.7 4INK-A nrPDB 30 3.0 1DT2-A nrPDB 29 3.5 2W7U-A nrPDB 29 4.6 1OFP-A nrPDB 29 4.7 1P1D-A nrPDB 28 6.8 5HM2-A nrPDB 28 7.0 4K1S-A nrPDB 28 8.7 2VZ5-A nrPDB 28 9.5 >4A8B-A nrPDB Length = 436 Score = 841 bits (2173), Expect = 0.0, Method: Compositional matrix adjust. Identities = 427/428 (99%), Positives = 428/428 (100%) Query: 28 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 87 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP Sbjct: 1 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60 Query: 88 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN Sbjct: 61 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180 Query: 208 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 267 SINRGN+GGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG Sbjct: 181 SINRGNAGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 240 Query: 268 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE Sbjct: 241 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 300 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD 387 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD Sbjct: 301 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD 360 Query: 388 GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGN 447 GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGN Sbjct: 361 GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGN 420 Query: 448 ESIYLLMR 455 ESIYLLMR Sbjct: 421 ESIYLLMR 428 >3STJ-A nrPDB Length = 345 Score = 664 bits (1713), Expect = 0.0, Method: Compositional matrix adjust. Identities = 337/337 (100%), Positives = 337/337 (100%) Query: 28 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 87 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP Sbjct: 1 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60 Query: 88 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN Sbjct: 61 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180 Query: 208 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 267 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG Sbjct: 181 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 240 Query: 268 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE Sbjct: 241 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 300 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSS 364 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSS Sbjct: 301 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSS 337 Score = 35.4 bits (80), Expect = 0.053, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 29/44 (65%) Query: 390 KGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLA 433 +G + EV+ GS +A+AG++ D+I +N +NS AE+R +A Sbjct: 263 RGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIA 306 >3MH6-A nrPDB Length = 456 Score = 505 bits (1300), Expect = e-143, Method: Compositional matrix adjust. Identities = 255/440 (57%), Positives = 332/440 (75%), Gaps = 26/440 (5%) Query: 39 LPSLAPMLEKVLPAVVSVRVEG-TASQGQKIPEEFKKFFGDDLP-DQPAQPFE------- 89 +PSLAPMLEKV+P+VVS+ VEG T ++P F++FFGDD P Q PF+ Sbjct: 12 MPSLAPMLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQSSPFCQG 71 Query: 90 --------------GLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSD 135 LGSGVII+A KGYV+TNNHV++ A I +QL+DGR+FDAK++G D Sbjct: 72 GQGGNGGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFDAKMVGKD 131 Query: 136 DQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLN 195 +SDIAL+QIQNP LT I +ADSD LRVGD+ VA+GNPFGLG+T TSGIVSALGRSGLN Sbjct: 132 PRSDIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSALGRSGLN 191 Query: 196 LEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLA 255 E ENFIQTDA+INRGNSGGAL+NLNGELIGINTAILAP GG++GIGFAIPSNM + L Sbjct: 192 AENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPSNMVKNLT 251 Query: 256 QQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIIT 315 Q++++G++KRG LGI GTE+++++AKA +D QRGAFVS+VLP S +AKAG+KAGD+IT Sbjct: 252 SQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGDVIT 311 Query: 316 SLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPAL 375 SLNGKP++SFA LR+++ T G+K+ LGLLR+GK + V + L S+ + + I + Sbjct: 312 SLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDSSSIFNGI 371 Query: 376 EGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAK 435 EGA +S+ K +G+ ++ V G+PAAQ GL+K DVIIG N+ V +IAE+RKVL +K Sbjct: 372 EGAEMSN---KGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAELRKVLDSK 428 Query: 436 PAIIALQIVRGNESIYLLMR 455 P+++AL I RG+ +IYLLM+ Sbjct: 429 PSVLALNIQRGDSTIYLLMQ 448 >3STI-A nrPDB Length = 245 Score = 471 bits (1211), Expect = e-133, Method: Compositional matrix adjust. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 28 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 87 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP Sbjct: 1 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60 Query: 88 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN Sbjct: 61 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180 Query: 208 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI 264 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI Sbjct: 181 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI 237 >3PV2-A nrPDB Length = 451 Score = 309 bits (792), Expect = 1e-84, Method: Compositional matrix adjust. Identities = 188/444 (42%), Positives = 269/444 (60%), Gaps = 29/444 (6%) Query: 34 ADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQP--------- 84 A+ +PS+AP+L+ ++PA+V+V V+G P G+D +QP Sbjct: 13 AEPPNMPSMAPVLKNIMPAIVNVAVQGYLPNDVTPPGSA----GNDEENQPNNRPPQSRM 68 Query: 85 ---AQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIA 141 + FE +GSGVII+ + G ++TN+HVI A I++ L DGR A+LIG D ++D+A Sbjct: 69 PEKGRKFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLA 128 Query: 142 LLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSALGRSGLNL 196 +L+I + L + I DSDKL VGDF VA+GNPFGL Q+AT GIVSAL RS LN+ Sbjct: 129 VLKI-DAKNLKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNI 187 Query: 197 EGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQ 256 EG+ENFIQTDA+IN GNSGGAL+N GELIGINTAIL+P GG+VGIGFAIP NM + +AQ Sbjct: 188 EGVENFIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGNVGIGFAIPINMVKDVAQ 247 Query: 257 QLIDFGEIKRGLLGIKGTEMSADIAKA--FNLDVQRGAFVSEVLPGSGSAKAGVKAGDII 314 Q+I FG I RGL+GI ++ ++A+A + D Q GA VS+V P S + AG+KAGDII Sbjct: 248 QIIKFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQ-GALVSQVNPNSPAELAGLKAGDII 306 Query: 315 TSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPA 374 T +N + ++++ I+ G+ VK+ + R+ KPL + + S + P Sbjct: 307 TQINDTKITQATQVKTTISLLRVGSTVKIIVERDNKPLTLSAVVTDIKSHEQKLQSNNPF 366 Query: 375 LEGATLSDGQLKDGGKGIKIDEVVKG----SPAAQAGLQKDDVIIGVNRDRVNSIAEMRK 430 L G L + + G I V G S +AG++ D+II N+ V + ++ Sbjct: 367 LYGLALRAFEQESPPHGNVIGVQVVGASENSAGWRAGIRPGDIIISANKKPVTDVKSLQT 426 Query: 431 VLAAKPAIIALQIVRGNESIYLLM 454 + K + +Q++RG S+YLL+ Sbjct: 427 IAQEKKKELLVQVLRGPGSMYLLV 450 >4YNN-A nrPDB Length = 448 Score = 300 bits (769), Expect = 6e-82, Method: Compositional matrix adjust. Identities = 182/452 (40%), Positives = 270/452 (59%), Gaps = 43/452 (9%) Query: 31 GQVADQAPLPSLAPMLEKVLPAVVSVRVEG-----------------TASQGQKIPEEFK 73 G D +PSLAP+L+ +PA+V+V V+G + Q +IPE+ + Sbjct: 11 GSAQDLTNMPSLAPVLKNAMPAIVNVAVQGYLPNNMASGNADDDDGENSKQPSRIPEKGR 70 Query: 74 KFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIG 133 KF E +GSGVII+ G ++TN+HVI A I++ L DGR A+LIG Sbjct: 71 KF-------------ESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIG 117 Query: 134 SDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSA 188 D ++D+A+L+I + L + I DSDKL VGD+ VA+GNPFGL Q+AT GIVSA Sbjct: 118 GDSETDLAVLKI-DAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSA 176 Query: 189 LGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPS 248 L RS LN+EG+ENFIQTDA+IN GN+GGAL+N GELIGINTAI++P GG+VGIGFAIP Sbjct: 177 LKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPI 236 Query: 249 NMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKA--FNLDVQRGAFVSEVLPGSGSAKA 306 NMA+ +AQQ+I FG I RGL+GI ++ ++A++ + D Q GA VS+V S + A Sbjct: 237 NMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQ-GALVSQVNQNSPAQLA 295 Query: 307 GVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSA 366 G+K+GD+I +N + ++++ I+ G+ K+ +LR+ KPL ++V + Sbjct: 296 GLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQ 355 Query: 367 SAEMITPALEGATLSDGQLKD----GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRV 422 + P L G L + + + G+++ + S +AGL+ D+II N+ V Sbjct: 356 KLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPV 415 Query: 423 NSIAEMRKVLAAKPAIIALQIVRGNESIYLLM 454 I ++ V K + +Q++RG ++YLL+ Sbjct: 416 KDIKSLQAVAHEKGKQLLVQVLRGAGALYLLI 447 >3PV4-A nrPDB Length = 354 Score = 285 bits (728), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 163/338 (48%), Positives = 224/338 (66%), Gaps = 25/338 (7%) Query: 34 ADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQP--------- 84 A+ +PS+AP+L+ ++PA+V+V V+G P G+D +QP Sbjct: 13 AEPPNMPSMAPVLKNIMPAIVNVAVQGYLPNDVTPPGSA----GNDEENQPNNRPPQSRM 68 Query: 85 ---AQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIA 141 + FE +GSGVII+ + G ++TN+HVI A I++ L DGR A+LIG D ++D+A Sbjct: 69 PEKGRKFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLA 128 Query: 142 LLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSALGRSGLNL 196 +L+I + L + I DSDKL VGDF VA+GNPFGL Q+AT GIVSAL RS LN+ Sbjct: 129 VLKI-DAKNLKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNI 187 Query: 197 EGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQ 256 EG+ENFIQTDA+IN GNSGGAL+N GELIGINTAIL+P GG+VGIGFAIP NM + +AQ Sbjct: 188 EGVENFIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGNVGIGFAIPINMVKDVAQ 247 Query: 257 QLIDFGEIKRGLLGIKGTEMSADIAKA--FNLDVQRGAFVSEVLPGSGSAKAGVKAGDII 314 Q+I FG I RGL+GI ++ ++A+A + D Q GA VS+V P S + AG+KAGDII Sbjct: 248 QIIKFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQ-GALVSQVNPNSPAELAGLKAGDII 306 Query: 315 TSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPL 352 T +N + ++++ I+ G+ VK+ + R+ KPL Sbjct: 307 TQINDTKITQATQVKTTISLLRVGSTVKIIVERDNKPL 344 >4YO1-A nrPDB Length = 351 Score = 283 bits (723), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 162/353 (45%), Positives = 227/353 (64%), Gaps = 41/353 (11%) Query: 31 GQVADQAPLPSLAPMLEKVLPAVVSVRVEG-----------------TASQGQKIPEEFK 73 G D +PSLAP+L+ +PA+V+V V+G + Q +IPE+ + Sbjct: 11 GSAQDLTNMPSLAPVLKNAMPAIVNVAVQGYLPNNMASGNADDDDGENSKQPSRIPEKGR 70 Query: 74 KFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIG 133 KF E +GSGVII+ G ++TN+HVI A I++ L DGR A+LIG Sbjct: 71 KF-------------ESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIG 117 Query: 134 SDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSA 188 D ++D+A+L+I + L + I DSDKL VGD+ VA+GNPFGL Q+AT GIVSA Sbjct: 118 GDSETDLAVLKI-DAKNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSA 176 Query: 189 LGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPS 248 L RS LN+EG+ENFIQTDA+IN GN+GGAL+N GELIGINTAI++P GG+VGIGFAIP Sbjct: 177 LKRSDLNIEGVENFIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPI 236 Query: 249 NMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKA--FNLDVQRGAFVSEVLPGSGSAKA 306 NMA+ +AQQ+I FG I RGL+GI ++ ++A++ + D Q GA VS+V S + A Sbjct: 237 NMAKDVAQQIIKFGSIHRGLMGIFVQHLTPELAQSMGYAEDFQ-GALVSQVNQNSPAQLA 295 Query: 307 GVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKP--LEVEVT 357 G+K+GD+I +N + ++++ I+ G+ K+ +LR+ KP L+VEVT Sbjct: 296 GLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVT 348 Score = 28.9 bits (63), Expect = 4.8, Method: Compositional matrix adjust. Identities = 17/65 (26%), Positives = 36/65 (55%), Gaps = 2/65 (3%) Query: 390 KGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPA--IIALQIVRGN 447 +G + +V + SPA AGL+ DVI+ +N ++ +++ ++ A ++I+R N Sbjct: 279 QGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDN 338 Query: 448 ESIYL 452 + + L Sbjct: 339 KPLTL 343 >5Y2D-A nrPDB Length = 465 Score = 248 bits (634), Expect = 3e-66, Method: Compositional matrix adjust. Identities = 151/376 (40%), Positives = 226/376 (60%), Gaps = 19/376 (5%) Query: 72 FKKFFGDDLPDQPAQPFE-GLGSGVIINASKGYVLTNNHVINQAQKISIQL-NDGREFDA 129 F++FFGD P + E LGSGVII + GY++TNNHVI+ A KI + + +E+ A Sbjct: 69 FQQFFGDLGGMIPKERMERALGSGVII-SKDGYIVTNNHVIDGADKIKVTIPGSNKEYSA 127 Query: 130 KLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSAL 189 L+G+D +SD+A+++I L I +DS+ + VGD A+GNPFG+G++ T GIVSAL Sbjct: 128 TLVGTDSESDLAVIRI-TKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQGIVSAL 186 Query: 190 GRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 +SG+ + ENFIQTDASIN GNSGGAL++ G L+GINTAI++ GG+ GIGFAIPSN Sbjct: 187 NKSGIGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGNHGIGFAIPSN 246 Query: 250 MARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVK 309 M + QLI G+I+RG LG+ ++S D+ ++ D + GA V V S + KAG+ Sbjct: 247 MVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQNSY--DNKEGAVVISVEKDSPAKKAGIL 304 Query: 310 AGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTL----DTSTSSS 365 D+IT +NGK + + ELR+ I + P +V L ++R+ K +TL + + + Sbjct: 305 VWDLITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAERKNPNKKET 364 Query: 366 ASAE---------MITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIG 416 SA+ + L T +L D +G+ + +V + SPA QAG ++ ++I Sbjct: 365 ISAQNGAQGQLNGLQVEDLTQETKRSMRLSDDVQGVLVSQVNENSPAEQAGFRQGNIITK 424 Query: 417 VNRDRVNSIAEMRKVL 432 + V S+A+ L Sbjct: 425 IEEVEVKSVADFNHAL 440 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 27/48 (56%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAA 434 D +G + V K SPA +AG+ D+I VN +V + E+R ++ + Sbjct: 282 DNKEGAVVISVEKDSPAKKAGILVWDLITEVNGKKVKNTNELRNLIGS 329 >5Y28-A nrPDB Length = 357 Score = 233 bits (595), Expect = 1e-61, Method: Compositional matrix adjust. Identities = 132/289 (45%), Positives = 190/289 (65%), Gaps = 6/289 (2%) Query: 72 FKKFFGDDLPDQPAQPFE-GLGSGVIINASKGYVLTNNHVINQAQKISIQL-NDGREFDA 129 F++FFGD P + E LGSGVII + GY++TNNHVI+ A KI + + +E+ A Sbjct: 69 FQQFFGDLGGMIPKERMERALGSGVII-SKDGYIVTNNHVIDGADKIKVTIPGSNKEYSA 127 Query: 130 KLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSAL 189 L+G+D +SD+A+++I + L I +DS+ + VGD A+GNPFG+G++ T GIVSAL Sbjct: 128 TLVGTDSESDLAVIRITKDN-LPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQGIVSAL 186 Query: 190 GRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSN 249 +SG+ + ENFIQTDASIN GNSGGAL++ G L+GINTAI++ GG+ GIGFAIPSN Sbjct: 187 NKSGIGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGNHGIGFAIPSN 246 Query: 250 MARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVK 309 M + QLI G+I+RG LG+ ++S D+ ++ D + GA V V S + KAG+ Sbjct: 247 MVKDTVTQLIKTGKIERGYLGVGLQDLSGDLQNSY--DNKEGAVVISVEKDSPAKKAGIL 304 Query: 310 AGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTL 358 D+IT +NGK + + ELR+ I + P +V L ++R+ K +TL Sbjct: 305 VWDLITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTL 353 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 16/48 (33%), Positives = 27/48 (56%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAA 434 D +G + V K SPA +AG+ D+I VN +V + E+R ++ + Sbjct: 282 DNKEGAVVISVEKDSPAKKAGILVWDLITEVNGKKVKNTNELRNLIGS 329 >5JD8-A nrPDB Length = 334 Score = 212 bits (540), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 123/271 (45%), Positives = 174/271 (64%), Gaps = 5/271 (1%) Query: 91 LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 150 LGSGVI+ + KGY+LTN HVIN A++I + + +GR +A L+GSD+ +D+A+L+I + + Sbjct: 51 LGSGVIM-SDKGYILTNKHVINDAEQIIVAMQNGRISEALLVGSDNLTDLAVLKI-DATN 108 Query: 151 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 210 L I I + +GD +A+GNP+ LGQT T GI+SA GR GL+ G +NF+QTDASIN Sbjct: 109 LPVIPININRTPHIGDVVLAIGNPYNLGQTVTQGIISATGRIGLSSSGRQNFLQTDASIN 168 Query: 211 RGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 267 +GNSGGAL+N GEL+GINT G GIGFAIP+ +A + ++LI G + RG Sbjct: 169 QGNSGGALVNTLGELMGINTLSFDKSNNGETPEGIGFAIPTALATKVMEKLIRDGRVIRG 228 Query: 268 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 +GI G E A D G V +V P +A+AG+ GDII ++N KP S E Sbjct: 229 YIGITGEEYPPFNANDNGSDRVHGIKVKKVSPDGPAAQAGIHVGDIILNVNNKPATSVIE 288 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTL 358 ++A PGT + + LLRNG+ + V++T+ Sbjct: 289 TMDQVAEVRPGTTIPVLLLRNGQQIAVQITI 319 Score = 35.8 bits (81), Expect = 0.044, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 2/66 (3%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAE-MRKVLAAKP-AIIALQIV 444 D GIK+ +V PAAQAG+ D+I+ VN S+ E M +V +P I + ++ Sbjct: 248 DRVHGIKVKKVSPDGPAAQAGIHVGDIILNVNNKPATSVIETMDQVAEVRPGTTIPVLLL 307 Query: 445 RGNESI 450 R + I Sbjct: 308 RNGQQI 313 >3GCO-A nrPDB Length = 340 Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 121/271 (44%), Positives = 172/271 (63%), Gaps = 4/271 (1%) Query: 91 LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 150 LGSGVI++ +GY++TN HVIN A +I + L DGR F+A L+GSD +D+A+L+I Sbjct: 64 LGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 122 Query: 151 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 210 L I I +GD +A+GNP+ LGQT T GI+SA GR GLN G +NF+QTDASIN Sbjct: 123 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN 182 Query: 211 RGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 267 GNSGGAL+N GEL+GINT G GIGFAIP +A + +LI G + RG Sbjct: 183 PGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRG 242 Query: 268 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 +GI G E++ A+ +D +G V+EV P +A AG++ D+I S++ KP S E Sbjct: 243 YIGIGGREIAPLHAQGGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALE 302 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTL 358 +++A PG+ + + ++R+ K L ++VT+ Sbjct: 303 TMAQVAEIRPGSVIPVVVMRDDKQLTLQVTI 333 Score = 37.0 bits (84), Expect = 0.017, Method: Compositional matrix adjust. Identities = 21/65 (32%), Positives = 42/65 (64%), Gaps = 2/65 (3%) Query: 390 KGIKIDEVVKGSPAAQAGLQKDDVIIGV-NRDRVNSIAEMRKVLAAKP-AIIALQIVRGN 447 +GI ++EV PAA AG+Q +D+II V N+ ++++ M +V +P ++I + ++R + Sbjct: 265 QGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMAQVAEIRPGSVIPVVVMRDD 324 Query: 448 ESIYL 452 + + L Sbjct: 325 KQLTL 329 >5T69-A nrPDB Length = 367 Score = 187 bits (474), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 125/323 (38%), Positives = 188/323 (58%), Gaps = 22/323 (6%) Query: 51 PAVVSVRVEGTASQ-GQKIPEE--FKKFFGDDLPDQPAQP-FEGLGSGVIINASKGYVLT 106 PAVV + E ++ I ++ F++FFG P P + G GSG II+ S G +LT Sbjct: 40 PAVVRIDTETVVTRRTDPILDDPFFQEFFGRSFPVPPRERRIAGQGSGFIIDNS-GIILT 98 Query: 107 NNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ-NPSKLTQIAIADSDKLRVG 165 N HV++ A K+ + L DGR FD ++ G+D+ +D+A+++I+ S L + S L+VG Sbjct: 99 NAHVVDGASKVVVTLRDGRTFDGQVRGTDEVTDLAVVKIEPQGSALPVAPLGTSSNLQVG 158 Query: 166 DFAVAVGNPFGLGQTATSGIVSALGRS----GLNLEGLENFIQTDASINRGNSGGALLNL 221 D+A+AVGNP GL T T GI+S LGRS G+ + +E FIQTDA+IN GN+GG LLN Sbjct: 159 DWAIAVGNPVGLDNTVTLGIISTLGRSAAQAGIPDKRVE-FIQTDAAINPGNAGGPLLNA 217 Query: 222 NGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIA 281 GE+IGINTAI A + GIGFAIP + A+ + L G + +G++ ++ D A Sbjct: 218 RGEVIGINTAIRA---DATGIGFAIPIDQAKAIQNTLAAGGTVPHPYIGVQMMNITVDQA 274 Query: 282 KAFNLDVQR--------GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIA 333 + N + G V VLPG+ + +AG++ GD+I +++G P++ A L+ + Sbjct: 275 QQNNRNPNSPFIIPEVDGILVMRVLPGTPAERAGIRRGDVIVAVDGTPISDGARLQRIVE 334 Query: 334 TTEPGTKVKLGLLRNGKPLEVEV 356 +KL LLR + L + V Sbjct: 335 QAGLNKALKLDLLRGDRRLSLTV 357 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 41/67 (61%), Gaps = 2/67 (2%) Query: 391 GIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVL--AAKPAIIALQIVRGNE 448 GI + V+ G+PA +AG+++ DVI+ V+ ++ A +++++ A + L ++RG+ Sbjct: 292 GILVMRVLPGTPAERAGIRRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLLRGDR 351 Query: 449 SIYLLMR 455 + L ++ Sbjct: 352 RLSLTVQ 358 >3QO6-A nrPDB Length = 348 Score = 172 bits (435), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 113/296 (38%), Positives = 170/296 (57%), Gaps = 23/296 (7%) Query: 89 EGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNP 148 +G GSG + + +G+++TN HVI A + + L D FDAK++G D D+A+L+I P Sbjct: 52 QGSGSGFVWD-KQGHIVTNYHVIRGASDLRVTLADQTTFDAKVVGFDQDKDVAVLRIDAP 110 Query: 149 -SKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR---SGLNLEGLENFIQ 204 +KL I + S L VG A+GNPFGL T T+G++S L R S +++ IQ Sbjct: 111 KNKLRPIPVGVSADLLVGQKVFAIGNPFGLDHTLTTGVISGLRREISSAATGRPIQDVIQ 170 Query: 205 TDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI 264 TDA+IN GNSGG LL+ +G LIGINTAI +P G S G+GF+IP + + QL+ FG++ Sbjct: 171 TDAAINPGNSGGPLLDSSGTLIGINTAIYSPSGASSGVGFSIPVDTVGGIVDQLVRFGKV 230 Query: 265 KRGLLGIK-GTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKA-----------GD 312 R +LGIK + S + L V G V + P + KAG+++ GD Sbjct: 231 TRPILGIKFAPDQSVE-----QLGVS-GVLVLDAPPSGPAGKAGLQSTKRDGYGRLVLGD 284 Query: 313 IITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASA 368 IITS+NG +++ ++L + + G +V + +LR ++ VTL+ SA+A Sbjct: 285 IITSVNGTKVSNGSDLYRILDQCKVGDEVTVEVLRGDHKEKISVTLEPKPDESAAA 340 >6IEO-A nrPDB Length = 314 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 108/288 (37%), Positives = 162/288 (56%), Gaps = 22/288 (7%) Query: 89 EGL-GSGVIINASKGYVLTNNHVINQAQ------KISIQLNDGREFDAKLIGSDDQSDIA 141 EG+ GSGVI++ +GY++TNNHVI++A K ++ NDG+E A L+G D ++D+A Sbjct: 28 EGMQGSGVIVDG-RGYIVTNNHVISEAANNPSQFKTTVVFNDGKEVPANLVGRDPKTDLA 86 Query: 142 LLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR------SGLN 195 +L++ N LT + DS K+RVGD +AVG P GL T T GIVSAL R G + Sbjct: 87 VLKVDNVDNLTVARLGDSSKVRVGDEVLAVGAPLGLRSTVTQGIVSALHRPVPLSGEGSD 146 Query: 196 LEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLA 255 + + + IQTDASIN GNSGG L++++ ++IGINTA + + G+GFAIP N + +A Sbjct: 147 TDTVIDAIQTDASINHGNSGGPLIDMDAQVIGINTAGKSLSDSASGLGFAIPVNEMKLVA 206 Query: 256 QQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIIT 315 LI G+I LGI +S IA GA V+ V GS + K G+ D+I Sbjct: 207 NSLIKDGKIVHPTLGISTRSVSNAIAS--------GAQVANVKAGSPAQKGGILENDVIV 258 Query: 316 SLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTS 363 + + + E + G + ++R G+ + + V D ++ Sbjct: 259 KVGNRAVADSDEFVVAVRQLAIGQDAPIEVVREGRHVTLTVKPDPDST 306 >4IC6-A nrPDB Length = 368 Score = 162 bits (411), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 113/302 (37%), Positives = 170/302 (56%), Gaps = 32/302 (10%) Query: 89 EGLGSGVIINASKGYVLTNNHVINQAQ-----------KISIQLNDG--REFDAKLIGSD 135 EG GSGV+ + +GY++TN HVI A +++I +DG + F+ KL+G+D Sbjct: 64 EGNGSGVVWDG-QGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGVQKNFEGKLVGAD 122 Query: 136 DQSDIALLQIQNPSKLTQ-IAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGL 194 D+A+L++ P L + I + S+ L+VG +A+GNPFG T T G++S L R Sbjct: 123 RAKDLAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVISGLNRDIF 182 Query: 195 NLEGLE--NFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMAR 252 + G+ IQTDA+IN GN+GG LL+ G LIGINTAI G S G+GFAIPS+ Sbjct: 183 SQTGVTIGGGIQTDAAINPGNAGGPLLDSKGNLIGINTAIFTQTGTSAGVGFAIPSSTVL 242 Query: 253 TLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKA-- 310 + QLI F ++ R + I E++ D A L+V+ GA V +V S + KAG+ Sbjct: 243 KIVPQLIQFSKVLRAGINI---ELAPD-PVANQLNVRNGALVLQVPGKSLAEKAGLHPTS 298 Query: 311 ---------GDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTS 361 GDII +++ KP+ + AEL + G KV L + R + LE++++L+ Sbjct: 299 RGFAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVTLKIKRGNEDLELKISLEEK 358 Query: 362 TS 363 +S Sbjct: 359 SS 360 >1L1J-A nrPDB Length = 239 Score = 161 bits (408), Expect = 5e-40, Method: Compositional matrix adjust. Identities = 94/234 (40%), Positives = 144/234 (61%), Gaps = 10/234 (4%) Query: 45 MLEKVLPAVVSVRVEGTASQGQKIP---EEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 ++E PAVV + V T P + FKK+FG+ LP + LGSG I + + Sbjct: 9 VVEACAPAVVKIDVVKTVKTSFFDPYFEQFFKKWFGE-LPPGFERQVASLGSGFIFD-PE 66 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ-NPSKLTQIAIADSD 160 GY+LTN HV+ A I++ + DG ++DA+ IG D++ DIA+++I+ + K + DSD Sbjct: 67 GYILTNYHVVGGADNITVTMLDGSKYDAEYIGGDEELDIAVIKIKASDKKFPYLEFGDSD 126 Query: 161 KLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENF---IQTDASINRGNSGGA 217 K+++G++A+A+GNP G T T G+VSA R +G + IQTDA+IN GNSGG Sbjct: 127 KVKIGEWAIAIGNPLGFQHTVTVGVVSATNRRIPKPDGSGYYVGLIQTDAAINPGNSGGP 186 Query: 218 LLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGI 271 LLN++GE+IGINTAI+ P +V +GFAIP N + ++ ++++ LG+ Sbjct: 187 LLNIHGEVIGINTAIVNP-QEAVNLGFAIPINTVKKFLDTILTQKKVEKAYLGV 239 >2QF3-A nrPDB Length = 243 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 91/179 (50%), Positives = 117/179 (65%), Gaps = 4/179 (2%) Query: 91 LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 150 LGSGVI++ +GY++TN HVIN A +I + L DGR F+A L+GSD +D+A+L+I Sbjct: 66 LGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 124 Query: 151 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 210 L I I +GD +A+GNP+ LGQT T GI+SA GR GLN G +NF+QTDASIN Sbjct: 125 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN 184 Query: 211 RGNSGGALLNLNGELIGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKR 266 GNSGGAL+N GEL+GINT G GIGFAIP +A + +LI G + R Sbjct: 185 HGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 243 >4RI0-A nrPDB Length = 332 Score = 158 bits (399), Expect = 5e-39, Method: Compositional matrix adjust. Identities = 114/316 (36%), Positives = 170/316 (53%), Gaps = 47/316 (14%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKK--FFGDDLPDQPAQPFEGLGSGVIINA 99 +A ++EK+ PAVV + E F + FG ++P GSG I++ Sbjct: 14 IADVVEKIAPAVVHI-------------ELFLRHPLFGRNVP-------LSSGSGFIMSE 53 Query: 100 SKGYVLTNNHVINQ------AQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQ 153 + G ++TN HV++ Q++ +QL +G ++A + D +SDIA ++I KL Sbjct: 54 A-GLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPV 112 Query: 154 IAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLE----NFIQTDASI 209 + + S LR G+F VA+G+PF L T T+GIVS R G L GL ++IQTDA I Sbjct: 113 LLLGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGREL-GLRDSDMDYIQTDAII 171 Query: 210 NRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLID--FGEIKRG 267 N GN+GG L+NL+GE+IGINT + + GI FAIPS+ + D + K+ Sbjct: 172 NYGNAGGPLVNLDGEVIGINTLKV-----TAGISFAIPSDRITRFLTEFQDKQIKDWKKR 226 Query: 268 LLGIKGTEMS---ADIAKAFNLD---VQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKP 321 +GI+ ++ D KA N D V G +V EV P S S + G++ GDII +NG+P Sbjct: 227 FIGIRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRP 286 Query: 322 LNSFAELRSRIATTEP 337 L +EL+ + T P Sbjct: 287 LVDSSELQEAVLTESP 302 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 43/84 (51%), Gaps = 4/84 (4%) Query: 371 ITPAL-EGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVN-RDRVNSIAEM 428 ITP+L + S+ + GI + EV SP+ + G+Q D+I+ VN R V+S Sbjct: 235 ITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVDSSELQ 294 Query: 429 RKVLAAKPAIIALQIVRGNESIYL 452 VL P + L++ RGN+ + Sbjct: 295 EAVLTESP--LLLEVRRGNDDLLF 316 >3NUM-A nrPDB Length = 332 Score = 156 bits (395), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 105/298 (35%), Positives = 164/298 (55%), Gaps = 40/298 (13%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK+ PAVV + E F+K LP + GSG I+ + Sbjct: 16 IADVVEKIAPAVVHI-------------ELFRK-----LPFSKREVPVASGSGFIV-SED 56 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK 161 G ++TN HV+ ++ ++L +G ++AK+ D+++DIAL++I + KL + + S + Sbjct: 57 GLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE 116 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLEN----FIQTDASINRGNSGGA 217 LR G+F VA+G+PF L T T+GIVS R G L GL N +IQTDA IN GN+GG Sbjct: 117 LRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKEL-GLRNSDMDYIQTDAIINYGNAGGP 175 Query: 218 LLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGE-----IKRGLLGIK 272 L+NL+GE+IGINT + + GI FAIPS+ + + D K+ +GI+ Sbjct: 176 LVNLDGEVIGINTLKV-----TAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIR 230 Query: 273 GTEMSADIAKAFN------LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS 324 +++ AK DV GA++ EV+P + + G+K D+I S+NG+ + S Sbjct: 231 MMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVS 288 Score = 34.7 bits (78), Expect = 0.085, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 36/62 (58%), Gaps = 1/62 (1%) Query: 391 GIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESI 450 G I EV+ +PA GL+++DVII +N V S ++ V+ + + + + + RGNE I Sbjct: 255 GAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSANDVSDVI-KRESTLNMVVRRGNEDI 313 Query: 451 YL 452 + Sbjct: 314 MI 315 >2R3U-A nrPDB Length = 211 Score = 155 bits (393), Expect = 3e-38, Method: Compositional matrix adjust. Identities = 90/175 (51%), Positives = 115/175 (65%), Gaps = 4/175 (2%) Query: 91 LGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSK 150 LGSGVI++ +GY++TN HVIN A +I + L DGR F+A L+GSD +D+A+L+I Sbjct: 38 LGSGVIMD-QRGYIITNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGG 96 Query: 151 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 210 L I I +GD +A+GNP+ LGQT T GI+SA GR GLN G +NF+QTDASIN Sbjct: 97 LPTIPINARRVPHIGDVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASIN 156 Query: 211 RGNSGGALLNLNGELIGINTAIL---APGGGSVGIGFAIPSNMARTLAQQLIDFG 262 GNSGGAL+N GEL+GINT G GIGFAIP +A + +LI G Sbjct: 157 HGNSGGALVNSLGELMGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDG 211 >2Z9I-A nrPDB Length = 324 Score = 151 bits (382), Expect = 5e-37, Method: Compositional matrix adjust. Identities = 112/290 (38%), Positives = 165/290 (56%), Gaps = 34/290 (11%) Query: 92 GSGVIINASKGYVLTNNHVINQAQK---------ISIQLNDGREFDAKLIGSDDQSDIAL 142 GSG+I++A +G +LTNNHVI A K ++ +DGR ++G+D SDIA+ Sbjct: 33 GSGIILSA-EGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAV 91 Query: 143 LQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR------SGLNL 196 +++Q S LT I++ S LRVG +A+G+P GL T T+GIVSAL R N Sbjct: 92 VRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQ 151 Query: 197 EGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGG-------GSVGIGFAIPSN 249 + + IQTDA+IN GNSGGAL+N+N +L+G+N+AI G GS+G+GFAIP + Sbjct: 152 NTVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVD 211 Query: 250 MARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVK 309 A+ +A +LI G+ LG++ T N GA + EV+ G +A AGV Sbjct: 212 QAKRIADELISTGKASHASLGVQVT----------NDKDTLGAKIVEVVAGGAAANAGVP 261 Query: 310 AGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR-NGKPLEVEVTL 358 G ++T ++ +P+NS L + + + PG V L +G V+VTL Sbjct: 262 KGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTL 311 >3TJO-A nrPDB Length = 231 Score = 134 bits (337), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 85/223 (38%), Positives = 128/223 (57%), Gaps = 29/223 (13%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK+ PAVV + E F+K LP + GSG I+ + Sbjct: 33 IADVVEKIAPAVVHI-------------ELFRK-----LPFSKREVPVASGSGFIV-SED 73 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK 161 G ++TN HV+ ++ ++L +G ++AK+ D+++DIAL++I + KL + + S + Sbjct: 74 GLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE 133 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLEN----FIQTDASINRGNSGGA 217 LR G+F VA+G+PF L T T+GIVS R G L GL N +IQTDA IN GN+GG Sbjct: 134 LRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKEL-GLRNSDMDYIQTDAIINYGNAGGP 192 Query: 218 LLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLID 260 L+NL+GE+IGINT + + GI FAIPS+ + + D Sbjct: 193 LVNLDGEVIGINTLKV-----TAGISFAIPSDKIKKFLTESHD 230 >5M3O-A nrPDB Length = 334 Score = 131 bits (330), Expect = 5e-31, Method: Compositional matrix adjust. Identities = 100/296 (33%), Positives = 157/296 (53%), Gaps = 49/296 (16%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK PAVV + + + F G ++P GSG ++ A+ Sbjct: 18 IADVVEKTAPAVVYIEIL-----------DRHPFLGREVPISN-------GSGFVV-AAD 58 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK 161 G ++TN HV+ +++ ++L G ++A + D +DIA L+IQ L + + S Sbjct: 59 GLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSAD 118 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLEN----FIQTDASINRGNSGGA 217 +R G+F VA+G+PF L T TSGIVS+ R +L GL +IQTDA+I+ GNSGG Sbjct: 119 VRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDL-GLPQTNVEYIQTDAAIDFGNSGGP 177 Query: 218 LLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTE-- 275 L+NL+GE+IG+NT + + GI FAIPS+ R + + GE K GI G++ Sbjct: 178 LVNLDGEVIGVNTMKV-----TAGISFAIPSDRLR----EFLHRGEKKNSSSGISGSQRR 228 Query: 276 --------MSADIAKAFNL------DVQRGAFVSEVLPGSGSAKAGVKAGDIITSL 317 +S I L DVQ G + +V+ GS + +AG++ GD+I ++ Sbjct: 229 YIGVMMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAI 284 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 43/75 (57%), Gaps = 1/75 (1%) Query: 380 LSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAII 439 L + D G+ I +V+ GSPA +AGL+ DVI+ + V + ++ + + + + + Sbjct: 247 LREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAEDVYEAVRTQ-SQL 305 Query: 440 ALQIVRGNESIYLLM 454 A+QI RG E++ L + Sbjct: 306 AVQIRRGRETLTLYV 320 >4IC5-A nrPDB Length = 291 Score = 113 bits (282), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 84/241 (34%), Positives = 122/241 (50%), Gaps = 27/241 (11%) Query: 45 MLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYV 104 + +K P+VV + + ++P K GD L D+ EG GSG + + G++ Sbjct: 45 LFQKTSPSVVYI-------EAIELP---KTSSGDILTDEENGKIEGTGSGFVWD-KLGHI 93 Query: 105 LTNNHVIN---------QAQKISIQLNDGREF--DAKLIGSDDQSDIALLQIQNPSK-LT 152 +TN HVI Q K+S+ G F + K++G D +D+A+L+I+ + L Sbjct: 94 VTNYHVIAKLATDQFGLQRCKVSLVDAKGTRFSKEGKIVGLDPDNDLAVLKIETEGRELN 153 Query: 153 QIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRS--GLNLEGLENFIQTDASIN 210 + + S+ LRVG A+GNP+G T T G+VS LGR N + + IQTDA IN Sbjct: 154 PVVLGTSNDLRVGQSCFAIGNPYGYENTLTIGVVSGLGREIPSPNGKSISEAIQTDADIN 213 Query: 211 RGNSGGALLNLNGELIGINTAILAPGGG--SVGIGFAIPSNMARTLAQQLIDFGEIKRGL 268 GN+GG LL+ G IG+NTA G S G+ FAIP + LI +G R Sbjct: 214 SGNAGGPLLDSYGHTIGVNTATFTRKGSGMSSGVNFAIPIDTVVRTVPYLIVYGTAYRDR 273 Query: 269 L 269 L Sbjct: 274 L 274 >4FLN-A nrPDB Length = 539 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 85/309 (27%), Positives = 137/309 (44%), Gaps = 48/309 (15%) Query: 80 LPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLIGSDDQS 138 LP Q + F GS +I G +LTN H + ++ ++ D R++ AK++ Sbjct: 64 LPWQKQRQFTSTGSAFMI--GDGKLLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVDC 121 Query: 139 DIALLQIQN--------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT--ATSGIVSA 188 DIALL +++ P +L + R+ D VG P G G T T G+VS Sbjct: 122 DIALLSVESEDFWKGAEPLRLGHLP-------RLQDSVTVVGYPLG-GDTISVTKGVVSR 173 Query: 189 LGRSGLNLEGLENF--IQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAI 246 + + G + IQ DA+IN GNSGG N GE IG+ + + IG+ I Sbjct: 174 IEVTSY-AHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGVAFQVYR-SEETENIGYVI 231 Query: 247 PSNMARTLAQQLIDF-------GEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLP 299 P+ + ++ L D+ G G+L ++ E A + + + G V V P Sbjct: 232 PTTV---VSHFLTDYERNGKYTGYPCLGVL-LQKLENPA-LRECLKVPTNEGVLVRRVEP 286 Query: 300 GSGSAKAGVKAGDIITSLNG--------KPLNSFAEL--RSRIATTEPGTKVKLGLLRNG 349 S ++K +K GD+I S + P S + R I+ G ++G++R G Sbjct: 287 TSDASKV-LKEGDVIVSFDDLHVGCEGTVPFRSSERIAFRYLISQKFAGDIAEIGIIRAG 345 Query: 350 KPLEVEVTL 358 + +V+V L Sbjct: 346 EHKKVQVVL 354 >5ILB-A nrPDB Length = 474 Score = 71.6 bits (174), Expect = 7e-13, Method: Compositional matrix adjust. Identities = 74/262 (28%), Positives = 122/262 (46%), Gaps = 41/262 (15%) Query: 80 LPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLIGSDDQS 138 LP Q + F GS +I K +LTN H + ++ ++ D R++ AK++ Sbjct: 24 LPWQKQRQFTSTGSAFMIGDGK--LLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVDC 81 Query: 139 DIALLQIQN--------PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQT--ATSGIVS- 187 DIALL +++ P +L + R+ D VG P G G T T G+VS Sbjct: 82 DIALLSVESEDFWKGAEPLRLGHLP-------RLQDSVTVVGYPLG-GDTISVTKGVVSR 133 Query: 188 ----ALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIG 243 + +L G IQ DA+IN GNSGG N GE IG+ + + IG Sbjct: 134 IEVTSYAHGSSDLLG----IQIDAAINPGNSGGPAFNDQGECIGVAFQVYR-SEETENIG 188 Query: 244 FAIPSNMARTLAQQLIDFGEIKRG----LLGIKGTEM-SADIAKAFNLD-VQRGAFVSEV 297 + IP+ + ++ L D+ + +LGI+ +M + D+ K+ ++ Q+G + + Sbjct: 189 YVIPTTV---VSHFLTDYERNGKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRIRRI 245 Query: 298 LPGSGSAKAGVKAGDIITSLNG 319 P + ++ +K DII S +G Sbjct: 246 EPTAPESQV-LKPSDIILSFDG 266 >5HM9-A nrPDB Length = 189 Score = 62.4 bits (150), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 46/162 (28%), Positives = 79/162 (48%), Gaps = 7/162 (4%) Query: 93 SGVIINASKGYVLTNNHVINQAQKISIQLNDG---REFDAKLIGSDDQSDIALLQIQNPS 149 SG I+ + GYV+T H +++ +IS+Q+ R F A+++ + D+ALL++Q Sbjct: 24 SGAIVG-TNGYVITTLHSVSKLPEISVQVATTGGIRRFPAQVVKTIPGHDLALLKMQTTE 82 Query: 150 KLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIV-SALGRSGLNLEGLENFIQTDAS 208 K +AD + G A G G+V SA + + + +++DA Sbjct: 83 KFLHFRMADVQTVVPGQQVFAFGRNMAGAPLVRQGLVQSADAPLAVGATQITHLLRSDAV 142 Query: 209 INRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNM 250 + +GG L+N G+L+GIN A P G GF +P+ + Sbjct: 143 YSWEQTGGPLVNAQGDLVGINIAATGPTGKVE--GFTVPAQV 182 >5JYK-A nrPDB Length = 566 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 70/255 (27%), Positives = 116/255 (45%), Gaps = 27/255 (10%) Query: 80 LPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLIGSDDQS 138 LP Q + + SG II + VLTN H + ++ ++ ++ A ++ + Sbjct: 116 LPWQRKRQYSSGSSGFIIGGRR--VLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTEC 173 Query: 139 DIALLQIQNPSKLTQIA-IADSDKLRVGDFAVAVGNPFGLGQT--ATSGIVSALG----- 190 DIALL + + ++ + D + D VG P G G T TSG+VS + Sbjct: 174 DIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGYPIG-GDTISVTSGVVSRMEILSYV 232 Query: 191 RSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNM 250 L GL Q DA+IN GNSGG N G+ +GI L IG+ IP+ + Sbjct: 233 HGSTELLGL----QIDAAINSGNSGGPAFNDKGKCVGIAFQSLKHEDAE-NIGYVIPTPV 287 Query: 251 ARTLAQQLIDFGEIKRG----LLGIKGTEM-SADIAKAFNLD-VQRGAFVSEVLPGSGSA 304 Q D+ + + +LGI+ +M + D+ K+ ++ Q+G + + P + + Sbjct: 288 IVHFIQ---DYEKHDKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRIRRIEPTAPES 344 Query: 305 KAGVKAGDIITSLNG 319 + +K DII S +G Sbjct: 345 QV-LKPSDIILSFDG 358 >3LT3-A nrPDB Length = 217 Score = 52.4 bits (124), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 52/200 (26%), Positives = 95/200 (47%), Gaps = 36/200 (18%) Query: 37 APLPSLA--PMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSG 94 +P P+L P++ P+VV +R A + QK+ E G+G Sbjct: 6 SPDPALVNNPVVAATEPSVVKIR--SLAPRCQKVLE---------------------GTG 42 Query: 95 VIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQI 154 +I+ + V+TN HV+ + +++ D + F+A ++ D D+A+L + + + Sbjct: 43 FVISPDR--VMTNAHVVAGSNNVTVYAGD-KPFEATVVSYDPSVDVAILAVPHLPPPPLV 99 Query: 155 AIADSDKLRVGDFAVAVGNPFGLGQTATSG-IVSALGRSGLNLEGLENFIQTD-----AS 208 A+ K G V +G P G TAT I A+ SG ++ G + D A Sbjct: 100 FAAEPAK--TGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRAD 157 Query: 209 INRGNSGGALLNLNGELIGI 228 + +G++GG L++LNG+++G+ Sbjct: 158 VEQGDAGGPLIDLNGQVLGV 177 >5ILA-A nrPDB Length = 301 Score = 51.2 bits (121), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 53/178 (29%), Positives = 79/178 (44%), Gaps = 17/178 (9%) Query: 80 LPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLIGSDDQS 138 LP Q + + SG II + VLTN H + ++ ++ ++ A ++ + Sbjct: 116 LPWQRKRQYSSGSSGFIIGGRR--VLTNAHSVEHHTQVKLKKRGSDTKYLATVLAIGTEC 173 Query: 139 DIALLQIQNPSKLTQIA-IADSDKLRVGDFAVAVGNPFGLGQT--ATSGIVSALG----- 190 DIALL + + ++ + D + D VG P G G T TSG+VS + Sbjct: 174 DIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGYPIG-GDTISVTSGVVSRMEILSYV 232 Query: 191 RSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPS 248 L GL Q DA+IN GNSGG N G+ +GI L IG+ IP+ Sbjct: 233 HGSTELLGL----QIDAAINSGNSGGPAFNDKGKCVGIAFQSLKHEDAE-NIGYVIPT 285 >2KL1-A nrPDB Length = 94 Score = 43.1 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 42/69 (60%), Gaps = 1/69 (1%) Query: 290 RGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNG 349 +G +V VLP +A ++AGD I +++G+P+N+ ++ S + + G +V++ +R+ Sbjct: 5 KGVYVMSVLPNMPAA-GRLEAGDRIAAIDGQPINTSEQIVSYVREKQAGDRVRVTFIRDR 63 Query: 350 KPLEVEVTL 358 K E E+ L Sbjct: 64 KQHEAELVL 72 >5C2Z-A nrPDB Length = 255 Score = 38.5 bits (88), Expect = 0.006, Method: Compositional matrix adjust. Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 12/96 (12%) Query: 151 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASIN 210 +T AI D+ ++ GD +G P+ T+T +L +S + + + F Q A Sbjct: 140 VTPAAIPDNVDVQKGDKISLLGYPY---NTSTH----SLYKSQIEVFNNQTF-QYFAYTE 191 Query: 211 RGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAI 246 GNSG + NL+GEL+GI++ GG G+ F I Sbjct: 192 PGNSGSGIFNLHGELVGIHSG----KGGQYGLPFGI 223 >1DUE-A nrPDB Length = 242 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 56/224 (25%), Positives = 97/224 (43%), Gaps = 57/224 (25%) Query: 59 EGTASQGQKIPEEFKKFFG---DDLP----------DQPAQPFEGLG----------SGV 95 E +A + +K E++ K++G +LP D+ P+ +G +GV Sbjct: 1 EVSAEEIKKHEEKWNKYYGVNAFNLPKELFSKVDEKDRQKYPYNTIGNVFVKGQTSATGV 60 Query: 96 IINASKGYVLTNNHVINQAQ--------KISIQLNDGR-------EFDAKLIGSDDQS-- 138 +I K VLTN H+ A + SI +D E++ K I + Sbjct: 61 LI--GKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEILQEPFGAG 118 Query: 139 -DIALLQI---QNP----SKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALG 190 D+AL+++ QN K++ I S+ L+ GD +G PF V+ + Sbjct: 119 VDLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLELIGYPF-------DHKVNQMH 171 Query: 191 RSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILA 234 RS + L L ++ GN+G + N NGEL+GI+++ ++ Sbjct: 172 RSEIELTTLSRGLRYYGFTVPGNAGSGIFNSNGELVGIHSSKVS 215 >2HII-A nrPDB Length = 257 Score = 35.8 bits (81), Expect = 0.038, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 9/55 (16%) Query: 331 RIATTEPGTKVKLG--------LLRNGKPLEVEVTLDTSTSSSASAEMITPALEG 377 RI+T E K++ G L KPL+ E+++DTS SSS SAEM A++G Sbjct: 158 RISTEEDKIKIEAGEEGKRYVAFLMKDKPLK-ELSIDTSASSSYSAEMFKDAVKG 211 >5MM8-A nrPDB Length = 204 Score = 34.7 bits (78), Expect = 0.094, Method: Compositional matrix adjust. Identities = 46/197 (23%), Positives = 85/197 (43%), Gaps = 37/197 (18%) Query: 87 PFEG---LGSGVIINASKGYVLTNNHVINQ----AQKISI---QLNDGREFDAK-LIGSD 135 P+ G +GSG K ++TN HV+ A I+ + N+G + K ++ Sbjct: 16 PYNGVVSIGSGTGFIVGKNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYS 75 Query: 136 DQSDIALLQIQNP------------SKLTQIA--IADSDKLRVGDFAVAVGNPFGLGQTA 181 Q DIA+L +++ + + +IA +++++ + + N F + ++ Sbjct: 76 GQEDIAILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYINKFQMYES- 134 Query: 182 TSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV- 240 T ++S G N I TDA + GNSG A+ N E++G++ PG S Sbjct: 135 TGKVLSVKG----------NMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKSTK 184 Query: 241 GIGFAIPSNMARTLAQQ 257 G G + + +A Sbjct: 185 GYGVYFSPEIKKFIADN 201 >2WV5-A nrPDB Length = 214 Score = 33.9 bits (76), Expect = 0.15, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 74/162 (45%), Gaps = 25/162 (15%) Query: 114 AQKISIQLNDGR----------EFDAKLIGSDDQSDIALLQIQNPSKLTQIA--IADSDK 161 A+K + DGR EF+ K+ G D SD AL+ + +K+ I D+ + Sbjct: 50 AEKYDKIMLDGRAMTDSDYRVFEFEIKVKGQDMLSDAALMVLHRGNKVRDITKHFRDTAR 109 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEG--LENFIQTDASINRGNSGGALL 219 ++ G V V N +G+ SG + ++G + A+ G +GGA+L Sbjct: 110 MKKGTPVVGVVNNADVGRLIFSGEALTYKDIVVLMDGDTMPGLFAYKAATRAGYAGGAVL 169 Query: 220 NLNGE---LIGINTAILAPGGGSVGIGFAIPSNMARTLAQQL 258 +G ++G ++A G G+G+ S ++R++ Q++ Sbjct: 170 AKDGADTFIVGTHSA------GGNGVGYC--SCVSRSMLQKM 203 >2DLS-A nrPDB Length = 93 Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 284 FNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKL 343 F + R V V PG + KAGVK GD I +NG + + + L + + G V L Sbjct: 23 FTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEV-VKLIKSGAYVAL 81 Query: 344 GLL 346 LL Sbjct: 82 TLL 84 >5E6P-B nrPDB Length = 88 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 22/63 (34%), Positives = 30/63 (47%), Gaps = 1/63 (1%) Query: 284 FNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKL 343 F + R V V PG + KAGVK GD I +NG + + + L + + G V L Sbjct: 22 FTVSGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEV-VKLIKSGAYVAL 80 Query: 344 GLL 346 LL Sbjct: 81 TLL 83 >2AS9-A nrPDB Length = 210 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 46/102 (45%), Gaps = 19/102 (18%) Query: 160 DKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALL 219 DK++V + + N F Q ++G + + + LN DA I GNSG +L Sbjct: 115 DKIKVIGYPLPAQNSFK--QFESTGTIKRIKDNILNF---------DAYIEPGNSGSPVL 163 Query: 220 NLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDF 261 N N E+IG ++ G G +G + N A Q+ DF Sbjct: 164 NSNNEVIG----VVYGGIGKIGSEY----NGAVYFTPQIKDF 197 >5A2P-A nrPDB Length = 163 Score = 32.3 bits (72), Expect = 0.47, Method: Compositional matrix adjust. Identities = 36/160 (22%), Positives = 67/160 (41%), Gaps = 24/160 (15%) Query: 288 VQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRS-RIATTEPGTKVKLGLL 346 V G FV V S ++ G++ GD + +NG+ ++ ++ ++ G K+ + + Sbjct: 23 VDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTI- 81 Query: 347 RNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQA 406 +P E VT+ +S G G KI +VK S AA+ Sbjct: 82 -RDRPFERTVTMHKDSSGHV----------GFIFKSG---------KITSIVKDSSAARN 121 Query: 407 GLQKDDVIIGVNRDRVNSI--AEMRKVLAAKPAIIALQIV 444 GL D I +N V + A++ +L+ ++ + I+ Sbjct: 122 GLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 161 >5G1D-A nrPDB Length = 201 Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust. Identities = 36/160 (22%), Positives = 67/160 (41%), Gaps = 24/160 (15%) Query: 288 VQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRS-RIATTEPGTKVKLGLL 346 V G FV V S ++ G++ GD + +NG+ ++ ++ ++ G K+ + + Sbjct: 35 VDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTI- 93 Query: 347 RNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQA 406 +P E VT+ +S G G KI +VK S AA+ Sbjct: 94 -RDRPFERTVTMHKDSSGHV----------GFIFKSG---------KITSIVKDSSAARN 133 Query: 407 GLQKDDVIIGVNRDRVNSI--AEMRKVLAAKPAIIALQIV 444 GL D I +N V + A++ +L+ ++ + I+ Sbjct: 134 GLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 173 >2KJP-A nrPDB Length = 91 Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 29/55 (52%) Query: 304 AKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTL 358 AK ++ GD I S +GK S +L I++ + G KV L + R K V +TL Sbjct: 14 AKGKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTLKIEREEKEKRVTLTL 68 >4O06-A nrPDB Length = 106 Score = 32.0 bits (71), Expect = 0.55, Method: Compositional matrix adjust. Identities = 21/68 (30%), Positives = 37/68 (54%), Gaps = 2/68 (2%) Query: 292 AFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRS--RIATTEPGTKVKLGLLRNG 349 AF+SEV+PGS S KA +K D + S+ + ++L++ + + + LLR G Sbjct: 21 AFISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREG 80 Query: 350 KPLEVEVT 357 + L+ +T Sbjct: 81 QILKTSLT 88 >4JCN-A nrPDB Length = 216 Score = 32.0 bits (71), Expect = 0.59, Method: Compositional matrix adjust. Identities = 41/158 (25%), Positives = 75/158 (47%), Gaps = 29/158 (18%) Query: 92 GSGVIINASKGYVLTNNHVINQAQ----KISIQLNDGREFD---AKLIGSD-----DQSD 139 GSGV++ ++ +LTN HV+N A+ IS+ + E D K +G + SD Sbjct: 36 GSGVVVGENE--ILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVGQEIIPYPGNSD 93 Query: 140 IALLQIQNPSKLTQ--------IAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR 191 +A+L++ P++ Q I+ + R+ + G P G + + ++G+ Sbjct: 94 LAILRVS-PNEHNQHIGQVVKPATISSNTDTRINENITVTGYP---GDKPLATMWESVGK 149 Query: 192 SGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGIN 229 + + G E ++ D S GNSG + N ++IGI+ Sbjct: 150 V-VYIGGEE--LRYDLSTVGGNSGSPVFNGKNQVIGIH 184 >2KBS-A nrPDB Length = 92 Score = 31.6 bits (70), Expect = 0.67, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNG 319 G F+S V PGS SA+ G++ GD I +NG Sbjct: 28 GIFISHVKPGSLSAEVGLEIGDQIVEVNG 56 >3K50-A nrPDB Length = 403 Score = 31.6 bits (70), Expect = 0.72, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 23/40 (57%) Query: 280 IAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNG 319 + K + D A +S V+PGS + +AG++ G I +NG Sbjct: 80 LYKVLDNDTAYNALISYVVPGSPAEEAGLQRGHWIMMMNG 119 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 394 IDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAE 427 I VV GSPA +AGLQ+ I+ +N D + E Sbjct: 94 ISYVVPGSPAEEAGLQRGHWIMMMNGDYITKKVE 127 >1X5N-A nrPDB Length = 114 Score = 31.2 bits (69), Expect = 0.88, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNG 319 G F+S V PGS SA+ G++ GD I +NG Sbjct: 42 GIFISHVKPGSLSAEVGLEIGDQIVEVNG 70 >3MN1-A nrPDB Length = 189 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 22/41 (53%), Gaps = 2/41 (4%) Query: 75 FFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQ 115 + GDDLPD P GLG V AS +V + H I +AQ Sbjct: 115 YLGDDLPDLPVIRRVGLGMAVANAAS--FVREHAHGITRAQ 153 >2PKT-A nrPDB Length = 91 Score = 30.8 bits (68), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 28/45 (62%) Query: 287 DVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSR 331 D ++ +S V PGS +A A + GD+IT+++G+ ++ L ++ Sbjct: 24 DFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQ 68 >4XZY-A nrPDB Length = 720 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 15/18 (83%) Query: 212 GNSGGALLNLNGELIGIN 229 GNSG ++N NGELIG+N Sbjct: 653 GNSGSPVMNANGELIGLN 670 >4QL6-A nrPDB Length = 634 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 31/113 (27%), Positives = 47/113 (41%), Gaps = 22/113 (19%) Query: 220 NLNGELIGINTA--ILAPGGGSVGIGFAIPSNMARTLAQQLIDF---------GEIKRGL 268 N IGIN ++P + I ++A +L F ++++G+ Sbjct: 177 NHENPYIGINDHGYRMSPEEEANSFHVRIIKSIAHSLDAHTAYFSQEEALSMRAQLEKGM 236 Query: 269 LGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGK 320 GI G + DI G V EVL G + K G ++ GDII +NGK Sbjct: 237 CGI-GVVLKEDID---------GVVVKEVLAGGPADKTGSLRVGDIIYRVNGK 279 >2V90-A nrPDB Length = 96 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 19/49 (38%), Positives = 29/49 (59%), Gaps = 2/49 (4%) Query: 286 LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFA--ELRSRI 332 LD + G F+ EV PG + KAG++AGD + ++ G+ + E SRI Sbjct: 26 LDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRI 74 >1AK5-A nrPDB Length = 503 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 39/168 (23%), Positives = 74/168 (44%), Gaps = 32/168 (19%) Query: 228 INTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIK------------GTE 275 N +L PG +V IPSN+ L+ L+ F + ++ + +K G + Sbjct: 12 FNEYLLIPGLSTVD---CIPSNV--NLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEK 66 Query: 276 MSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAEL------- 328 M+ +A+ + G+ E A KAG +++ N KP +FA++ Sbjct: 67 MAIALAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLAISQRT 126 Query: 329 -RSRIATTEPGTK--VKLGLLRNGKPLEVEVTLDTSTSSSASAEMITP 373 + +A T+ GT V LGL+ + + +D + + + ++M+TP Sbjct: 127 THNTVAVTDDGTPHGVLLGLV-----TQRDYPIDLTQTETKVSDMMTP 169 >3QDO-A nrPDB Length = 109 Score = 30.0 bits (66), Expect = 2.2, Method: Compositional matrix adjust. Identities = 14/27 (51%), Positives = 18/27 (66%) Query: 293 FVSEVLPGSGSAKAGVKAGDIITSLNG 319 VS VLPG + +AGV+ GD I +NG Sbjct: 46 HVSAVLPGGAADRAGVRKGDRILEVNG 72 >3I1E-A nrPDB Length = 90 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 4/65 (6%) Query: 294 VSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLE 353 V E +P +G + AGD+IT ++G+ S E I + + G VK+ K E Sbjct: 9 VKEDVPAAGI----LHAGDLITEIDGQSFKSSQEFIDYIHSKKVGDTVKIKYKHGNKNEE 64 Query: 354 VEVTL 358 + L Sbjct: 65 ASIKL 69 >4INK-A nrPDB Length = 205 Score = 29.6 bits (65), Expect = 3.0, Method: Compositional matrix adjust. Identities = 43/181 (23%), Positives = 72/181 (39%), Gaps = 41/181 (22%) Query: 87 PFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDA----------------K 130 P+ G+ + A G+V+ NH I + ++ + G E A K Sbjct: 16 PYSGV---TWMGAGTGFVV-GNHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTK 71 Query: 131 LIGSDDQSDIALLQIQNPSK----------LTQIAIADSDKLRVGDFAVAVGNPFG--LG 178 ++ + DIA++Q++ S ++ IA K + NP G L Sbjct: 72 IVDYPGKEDIAVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQ 131 Query: 179 QTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGG 238 ++G V L++ G N + +DA + G+SG +LN E IG+ A P G Sbjct: 132 MYESTGKV-------LSVNG--NIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGE 182 Query: 239 S 239 S Sbjct: 183 S 183 >1DT2-A nrPDB Length = 245 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 12/19 (63%), Positives = 15/19 (78%) Query: 212 GNSGGALLNLNGELIGINT 230 GNSG + NL GELIGI++ Sbjct: 183 GNSGSGIFNLKGELIGIHS 201 >2W7U-A nrPDB Length = 200 Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust. Identities = 14/27 (51%), Positives = 17/27 (62%) Query: 202 FIQTDASINRGNSGGALLNLNGELIGI 228 F++ DA GNSG +LN ELIGI Sbjct: 142 FMEFDAYAQPGNSGSPVLNSKHELIGI 168 >1OFP-A nrPDB Length = 370 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 14/38 (36%), Positives = 23/38 (60%) Query: 120 QLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIA 157 ++N G E D +++G D + ALLQ+Q P+ T + A Sbjct: 14 KVNQGAEEDVRILGYDPLASPALLQVQIPATPTSLETA 51 >1P1D-A nrPDB Length = 196 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 40/172 (23%), Positives = 74/172 (43%), Gaps = 32/172 (18%) Query: 276 MSADIAKAFNLDVQRGAFVSEVLPG----------SGSAKAGV-KAGDIITSLNGKPL-- 322 ++AD F + +Q F +E L S + + GV + GD + ++NG P Sbjct: 12 LTADPVTGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTED 71 Query: 323 NSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTS---SSASAEMITPALE--- 376 ++F E + + +KV L E+ D + S SS + + P Sbjct: 72 STFEEANQLLRDSSITSKVTL-----------EIEFDVAESVIPSSGTFHVKLPKKHSVE 120 Query: 377 -GATLSDGQLKDGGKGIKIDEVVKGSPAAQAG-LQKDDVIIGVNRDRVNSIA 426 G T+S + G + I ++ KGS A + G L+ D ++ ++ R++S + Sbjct: 121 LGITISSPSSRKPGDPLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDSCS 172 >5HM2-A nrPDB Length = 209 Score = 28.5 bits (62), Expect = 7.0, Method: Compositional matrix adjust. Identities = 34/140 (24%), Positives = 63/140 (45%), Gaps = 15/140 (10%) Query: 126 EFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRV--GDFAVAVGNPFGLGQTATS 183 EF+ K+ G D SD AL+ + ++ I + D++ + G + V N +G+ S Sbjct: 72 EFEVKVKGQDMMSDAALMVLNRGQRVRDITMHFRDQVHIKKGTPVLGVINNADVGRLIFS 131 Query: 184 GIVSALGRSGLNLEG--LENFIQTDASINRGNSGGALLNLNGE---LIGINTAILAPGGG 238 G + ++G + A G +GGA++ +G +IG ++A G Sbjct: 132 GDALTYKDVVVAMDGDTMPGLFAYRAGTKVGYAGGAVMTKDGAHTVIIGTHSA------G 185 Query: 239 SVGIGFAIPSNMARTLAQQL 258 G+G+ S ++R+ QL Sbjct: 186 GNGVGYC--SCVSRSSLLQL 203 >4K1S-A nrPDB Length = 206 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 14/29 (48%), Positives = 17/29 (58%) Query: 203 IQTDASINRGNSGGALLNLNGELIGINTA 231 I A GNSG +LN N EL+GI+ A Sbjct: 148 IVYSAHTESGNSGSPVLNSNNELVGIHFA 176 >2VZ5-A nrPDB Length = 139 Score = 27.7 bits (60), Expect = 9.5, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 18/29 (62%) Query: 390 KGIKIDEVVKGSPAAQAGLQKDDVIIGVN 418 KGI + V +G PA AGLQ D I+ VN Sbjct: 64 KGIYVTRVSEGGPAEIAGLQIGDKIMQVN 92 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4A8B-A nrPDB 560 e-160 3MH6-A nrPDB 488 e-138 3PV2-A nrPDB 484 e-137 4YNN-A nrPDB 480 e-136 3STJ-A nrPDB 442 e-124 5Y2D-A nrPDB 410 e-115 3PV4-A nrPDB 373 e-103 4YO1-A nrPDB 372 e-103 5Y28-A nrPDB 341 4e-94 3STI-A nrPDB 334 7e-92 3GCO-A nrPDB 322 2e-88 5JD8-A nrPDB 306 2e-83 5T69-A nrPDB 299 1e-81 3QO6-A nrPDB 296 2e-80 3NUM-A nrPDB 291 4e-79 4RI0-A nrPDB 285 2e-77 4IC6-A nrPDB 269 1e-72 1L1J-A nrPDB 268 3e-72 6IEO-A nrPDB 267 8e-72 4FLN-A nrPDB 264 5e-71 5ILB-A nrPDB 258 4e-69 5M3O-A nrPDB 253 9e-68 5JYK-A nrPDB 251 5e-67 3TJO-A nrPDB 231 4e-61 2QF3-A nrPDB 230 8e-61 2R3U-A nrPDB 226 2e-59 2Z9I-A nrPDB 218 4e-57 4IC5-A nrPDB 216 1e-56 5ILA-A nrPDB 185 4e-47 5HM9-A nrPDB 152 2e-37 3LT3-A nrPDB 131 7e-31 2KL1-A nrPDB 85 8e-17 Sequences not found previously or not previously below threshold: 1DUE-A nrPDB 67 1e-11 4INK-A nrPDB 61 1e-09 2AS9-A nrPDB 60 2e-09 2KJP-A nrPDB 60 3e-09 2KJK-A nrPDB 58 8e-09 3I1E-A nrPDB 58 9e-09 5MM8-A nrPDB 57 1e-08 2W7U-A nrPDB 57 2e-08 3I18-A nrPDB 56 5e-08 5C2Z-A nrPDB 55 6e-08 1DT2-A nrPDB 54 1e-07 4JCN-A nrPDB 54 1e-07 4QL6-A nrPDB 53 2e-07 1P1D-A nrPDB 52 5e-07 4K1S-A nrPDB 51 1e-06 2XKX-A nrPDB 50 2e-06 4JJ3-A nrPDB 50 2e-06 1WCZ-A nrPDB 49 3e-06 5G1D-A nrPDB 47 1e-05 5A2P-A nrPDB 47 2e-05 4FGM-A nrPDB 47 2e-05 5E6P-B nrPDB 46 3e-05 2L4S-A nrPDB 46 4e-05 2DLS-A nrPDB 46 5e-05 2VZ5-A nrPDB 44 9e-05 2V90-A nrPDB 44 1e-04 2PKT-A nrPDB 44 1e-04 2HLC-A nrPDB 42 4e-04 4C2G-A nrPDB 42 5e-04 3TSW-A nrPDB 42 5e-04 3SHW-A nrPDB 42 5e-04 5ZDS-A nrPDB 42 5e-04 4O06-A nrPDB 41 0.001 4Q2Q-A nrPDB 40 0.001 3TSV-A nrPDB 40 0.002 1UF1-A nrPDB 39 0.003 3K50-A nrPDB 39 0.003 3QDO-A nrPDB 39 0.003 2QBW-A nrPDB 39 0.004 1FC9-A nrPDB 39 0.004 3SHU-A nrPDB 39 0.004 3CH8-A nrPDB 39 0.004 1UEZ-A nrPDB 39 0.005 2KBS-A nrPDB 38 0.010 1M5Z-A nrPDB 38 0.011 5N7D-A nrPDB 38 0.011 3K1R-A nrPDB 37 0.012 1X5N-A nrPDB 37 0.014 2LOB-A nrPDB 37 0.019 2R4H-A nrPDB 37 0.019 1MFG-A nrPDB 37 0.019 1AZZ-A nrPDB 37 0.021 4XZY-A nrPDB 36 0.025 1WFV-A nrPDB 36 0.026 5HJ1-A nrPDB 36 0.029 3CYY-A nrPDB 36 0.029 1UEQ-A nrPDB 36 0.034 2JIL-A nrPDB 36 0.035 3G8Q-A nrPDB 35 0.045 5JWG-A nrPDB 35 0.052 5JXF-A nrPDB 35 0.053 2RCZ-A nrPDB 35 0.053 4JOF-A nrPDB 35 0.062 3WOM-A nrPDB 35 0.066 2DC2-A nrPDB 35 0.066 4NXP-A nrPDB 35 0.072 2D8I-A nrPDB 35 0.078 1X5R-A nrPDB 35 0.079 2QT5-A nrPDB 35 0.080 1YJS-A nrPDB 35 0.080 1P3E-A nrPDB 35 0.081 1PQ7-A nrPDB 35 0.082 4WSI-A nrPDB 35 0.086 1FUJ-A nrPDB 34 0.12 2SFA-A nrPDB 34 0.13 3BPU-A nrPDB 34 0.17 2I6V-A nrPDB 33 0.24 2WV5-A nrPDB 33 0.28 3PVL-A nrPDB 33 0.31 3SOE-A nrPDB 33 0.31 2I4S-A nrPDB 33 0.33 1CT4-E nrPDB 33 0.34 6FAH-A nrPDB 32 0.41 1UJD-A nrPDB 32 0.52 2YO3-A nrPDB 32 0.67 1MBM-A nrPDB 31 0.89 5WDX-A nrPDB 31 0.94 1UEW-A nrPDB 31 0.97 1V6B-A nrPDB 31 1.0 5MV8-B nrPDB 31 1.0 6C2N-A nrPDB 31 1.1 3EGH-C nrPDB 31 1.1 2SGA-A nrPDB 31 1.2 5GT5-A nrPDB 31 1.3 5MRR-A nrPDB 30 1.6 3AQ1-B nrPDB 30 1.7 1GBE-A nrPDB 30 1.7 2YT8-A nrPDB 30 2.5 3FAO-A nrPDB 30 3.0 3U1J-B nrPDB 29 3.5 2MX6-A nrPDB 29 3.7 1TXO-A nrPDB 29 4.1 1V62-A nrPDB 29 5.7 4RTF-D nrPDB 28 8.0 >4A8B-A nrPDB Length = 436 Score = 560 bits (1443), Expect = e-160, Method: Composition-based stats. Identities = 427/428 (99%), Positives = 428/428 (100%) Query: 28 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 87 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP Sbjct: 1 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60 Query: 88 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN Sbjct: 61 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180 Query: 208 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 267 SINRGN+GGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG Sbjct: 181 SINRGNAGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 240 Query: 268 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE Sbjct: 241 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 300 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD 387 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD Sbjct: 301 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD 360 Query: 388 GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGN 447 GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGN Sbjct: 361 GGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGN 420 Query: 448 ESIYLLMR 455 ESIYLLMR Sbjct: 421 ESIYLLMR 428 >3MH6-A nrPDB Length = 456 Score = 488 bits (1256), Expect = e-138, Method: Composition-based stats. Identities = 253/447 (56%), Positives = 329/447 (73%), Gaps = 26/447 (5%) Query: 32 QVADQAPLPSLAPMLEKVLPAVVSVRVEG-TASQGQKIPEEFKKFFGDDLPDQPAQ---- 86 +PSLAPMLEKV+P+VVS+ VEG T ++P F++FFGDD P Sbjct: 5 SATTAQQMPSLAPMLEKVMPSVVSINVEGSTTVNTPRMPRNFQQFFGDDSPFCQEGSPFQ 64 Query: 87 ------------------PFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFD 128 F LGSGVII+A KGYV+TNNHV++ A I +QL+DGR+FD Sbjct: 65 SSPFCQGGQGGNGGGQQQKFMALGSGVIIDADKGYVVTNNHVVDNATVIKVQLSDGRKFD 124 Query: 129 AKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSA 188 AK++G D +SDIAL+QIQNP LT I +ADSD LRVGD+ VA+GNPFGLG+T TSGIVSA Sbjct: 125 AKMVGKDPRSDIALIQIQNPKNLTAIKMADSDALRVGDYTVAIGNPFGLGETVTSGIVSA 184 Query: 189 LGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPS 248 LGRSGLN E ENFIQTDA+INRGNSGGAL+NLNGELIGINTAILAP GG++GIGFAIPS Sbjct: 185 LGRSGLNAENYENFIQTDAAINRGNSGGALVNLNGELIGINTAILAPDGGNIGIGFAIPS 244 Query: 249 NMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGV 308 NM + L Q++++G++KRG LGI GTE+++++AKA +D QRGAFVS+VLP S +AKAG+ Sbjct: 245 NMVKNLTSQMVEYGQVKRGELGIMGTELNSELAKAMKVDAQRGAFVSQVLPNSSAAKAGI 304 Query: 309 KAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASA 368 KAGD+ITSLNGKP++SFA LR+++ T G+K+ LGLLR+GK + V + L S+ + + Sbjct: 305 KAGDVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLRDGKQVNVNLELQQSSQNQVDS 364 Query: 369 EMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEM 428 I +EGA +S+ K +G+ ++ V G+PAAQ GL+K DVIIG N+ V +IAE+ Sbjct: 365 SSIFNGIEGAEMSN---KGKDQGVVVNNVKTGTPAAQIGLKKGDVIIGANQQAVKNIAEL 421 Query: 429 RKVLAAKPAIIALQIVRGNESIYLLMR 455 RKVL +KP+++AL I RG+ +IYLLM+ Sbjct: 422 RKVLDSKPSVLALNIQRGDSTIYLLMQ 448 >3PV2-A nrPDB Length = 451 Score = 484 bits (1245), Expect = e-137, Method: Composition-based stats. Identities = 184/440 (41%), Positives = 267/440 (60%), Gaps = 19/440 (4%) Query: 33 VADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEF---KKFFGDDLPDQ-----P 84 A+ +PS+AP+L+ ++PA+V+V V+G P ++ ++ P Q Sbjct: 12 SAEPPNMPSMAPVLKNIMPAIVNVAVQGYLPNDVTPPGSAGNDEENQPNNRPPQSRMPEK 71 Query: 85 AQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQ 144 + FE +GSGVII+ + G ++TN+HVI A I++ L DGR A+LIG D ++D+A+L+ Sbjct: 72 GRKFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLAVLK 131 Query: 145 IQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSALGRSGLNLEGL 199 I L + I DSDKL VGDF VA+GNPFGL Q+AT GIVSAL RS LN+EG+ Sbjct: 132 IDA-KNLKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGV 190 Query: 200 ENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLI 259 ENFIQTDA+IN GNSGGAL+N GELIGINTAIL+P GG+VGIGFAIP NM + +AQQ+I Sbjct: 191 ENFIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGNVGIGFAIPINMVKDVAQQII 250 Query: 260 DFGEIKRGLLGIKGTEMSADIAKAFN-LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLN 318 FG I RGL+GI ++ ++A+A + +GA VS+V P S + AG+KAGDIIT +N Sbjct: 251 KFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGDIITQIN 310 Query: 319 GKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGA 378 + ++++ I+ G+ VK+ + R+ KPL + + S + P L G Sbjct: 311 DTKITQATQVKTTISLLRVGSTVKIIVERDNKPLTLSAVVTDIKSHEQKLQSNNPFLYGL 370 Query: 379 TLSDGQLKDGGKGIKIDEVVKG----SPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAA 434 L + + G I V G S +AG++ D+II N+ V + ++ + Sbjct: 371 ALRAFEQESPPHGNVIGVQVVGASENSAGWRAGIRPGDIIISANKKPVTDVKSLQTIAQE 430 Query: 435 KPAIIALQIVRGNESIYLLM 454 K + +Q++RG S+YLL+ Sbjct: 431 KKKELLVQVLRGPGSMYLLV 450 >4YNN-A nrPDB Length = 448 Score = 480 bits (1235), Expect = e-136, Method: Composition-based stats. Identities = 176/438 (40%), Positives = 265/438 (60%), Gaps = 15/438 (3%) Query: 31 GQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQ----GQKIPEEFKKFFGDDLPDQPAQ 86 G D +PSLAP+L+ +PA+V+V V+G G ++ + + + Sbjct: 11 GSAQDLTNMPSLAPVLKNAMPAIVNVAVQGYLPNNMASGNADDDDGENSKQPSRIPEKGR 70 Query: 87 PFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ 146 FE +GSGVII+ G ++TN+HVI A I++ L DGR A+LIG D ++D+A+L+I Sbjct: 71 KFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKID 130 Query: 147 NPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSALGRSGLNLEGLEN 201 L + I DSDKL VGD+ VA+GNPFGL Q+AT GIVSAL RS LN+EG+EN Sbjct: 131 A-KNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVEN 189 Query: 202 FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDF 261 FIQTDA+IN GN+GGAL+N GELIGINTAI++P GG+VGIGFAIP NMA+ +AQQ+I F Sbjct: 190 FIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKF 249 Query: 262 GEIKRGLLGIKGTEMSADIAKAFN-LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK 320 G I RGL+GI ++ ++A++ + +GA VS+V S + AG+K+GD+I +N Sbjct: 250 GSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDT 309 Query: 321 PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATL 380 + ++++ I+ G+ K+ +LR+ KPL ++V + + P L G L Sbjct: 310 KITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSNNPFLYGLAL 369 Query: 381 SDGQLKDGGK----GIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKP 436 + + + G+++ + S +AGL+ D+II N+ V I ++ V K Sbjct: 370 RNFEQESPPHGNVVGVQVVGASETSAGWRAGLRPGDIIISANKTPVKDIKSLQAVAHEKG 429 Query: 437 AIIALQIVRGNESIYLLM 454 + +Q++RG ++YLL+ Sbjct: 430 KQLLVQVLRGAGALYLLI 447 >3STJ-A nrPDB Length = 345 Score = 442 bits (1136), Expect = e-124, Method: Composition-based stats. Identities = 337/337 (100%), Positives = 337/337 (100%) Query: 28 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 87 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP Sbjct: 1 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60 Query: 88 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN Sbjct: 61 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180 Query: 208 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 267 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG Sbjct: 181 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG 240 Query: 268 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE Sbjct: 241 LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 300 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSS 364 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSS Sbjct: 301 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSS 337 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 18/48 (37%), Positives = 30/48 (62%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAA 434 D +G + EV+ GS +A+AG++ D+I +N +NS AE+R +A Sbjct: 260 DVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIAT 307 >5Y2D-A nrPDB Length = 465 Score = 410 bits (1054), Expect = e-115, Method: Composition-based stats. Identities = 160/444 (36%), Positives = 249/444 (56%), Gaps = 30/444 (6%) Query: 24 QAVASIPGQVADQAPLPSLA---PMLEKVLPAVVSVRVEGTASQ-----GQKIPEEFKKF 75 Q++ + +V+ + ++ ++ + AVV++ E G F++F Sbjct: 13 QSMPKVKERVSVPSKDDTIYSYHDSIKDSIKAVVNISTEKKIKNNFIGGGVFNDPFFQQF 72 Query: 76 FGDDLPDQPAQPFE-GLGSGVIINASKGYVLTNNHVINQAQKISIQL-NDGREFDAKLIG 133 FGD P + E LGSGVII+ GY++TNNHVI+ A KI + + +E+ A L+G Sbjct: 73 FGDLGGMIPKERMERALGSGVIIS-KDGYIVTNNHVIDGADKIKVTIPGSNKEYSATLVG 131 Query: 134 SDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSG 193 +D +SD+A+++I L I +DS+ + VGD A+GNPFG+G++ T GIVSAL +SG Sbjct: 132 TDSESDLAVIRI-TKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQGIVSALNKSG 190 Query: 194 LNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMART 253 + + ENFIQTDASIN GNSGGAL++ G L+GINTAI++ GG+ GIGFAIPSNM + Sbjct: 191 IGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGNHGIGFAIPSNMVKD 250 Query: 254 LAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDI 313 QLI G+I+RG LG+ ++S D+ ++ D + GA V V S + KAG+ D+ Sbjct: 251 TVTQLIKTGKIERGYLGVGLQDLSGDLQNSY--DNKEGAVVISVEKDSPAKKAGILVWDL 308 Query: 314 ITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTL----DTSTSSSASAE 369 IT +NGK + + ELR+ I + P +V L ++R+ K +TL + + + SA+ Sbjct: 309 ITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAERKNPNKKETISAQ 368 Query: 370 ---------MITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRD 420 + L T +L D +G+ + +V + SPA QAG ++ ++I + Sbjct: 369 NGAQGQLNGLQVEDLTQETKRSMRLSDDVQGVLVSQVNENSPAEQAGFRQGNIITKIEEV 428 Query: 421 RVNSIAEMRKVLAA---KPAIIAL 441 V S+A+ L KP + Sbjct: 429 EVKSVADFNHALEKYKGKPKRFLV 452 >3PV4-A nrPDB Length = 354 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 159/344 (46%), Positives = 224/344 (65%), Gaps = 15/344 (4%) Query: 33 VADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEF---KKFFGDDLPDQ-----P 84 A+ +PS+AP+L+ ++PA+V+V V+G P ++ ++ P Q Sbjct: 12 SAEPPNMPSMAPVLKNIMPAIVNVAVQGYLPNDVTPPGSAGNDEENQPNNRPPQSRMPEK 71 Query: 85 AQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQ 144 + FE +GSGVII+ + G ++TN+HVI A I++ L DGR A+LIG D ++D+A+L+ Sbjct: 72 GRKFESIGSGVIIDPNNGVIITNDHVIRNASLITVTLQDGRRLKARLIGGDSETDLAVLK 131 Query: 145 IQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSALGRSGLNLEGL 199 I L + I DSDKL VGDF VA+GNPFGL Q+AT GIVSAL RS LN+EG+ Sbjct: 132 IDA-KNLKSLVIGDSDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGV 190 Query: 200 ENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLI 259 ENFIQTDA+IN GNSGGAL+N GELIGINTAIL+P GG+VGIGFAIP NM + +AQQ+I Sbjct: 191 ENFIQTDAAINPGNSGGALVNAKGELIGINTAILSPYGGNVGIGFAIPINMVKDVAQQII 250 Query: 260 DFGEIKRGLLGIKGTEMSADIAKAFN-LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLN 318 FG I RGL+GI ++ ++A+A + +GA VS+V P S + AG+KAGDIIT +N Sbjct: 251 KFGSIHRGLMGIFVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGDIITQIN 310 Query: 319 GKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTST 362 + ++++ I+ G+ VK+ + R+ KPL + + Sbjct: 311 DTKITQATQVKTTISLLRVGSTVKIIVERDNKPLTLSAVVTDIK 354 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 35/80 (43%), Gaps = 2/80 (2%) Query: 375 LEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLA- 433 L + +G + +V SPA AGL+ D+I +N ++ +++ ++ Sbjct: 267 LTPELAQAMGYPEDFQGALVSQVNPNSPAELAGLKAGDIITQINDTKITQATQVKTTISL 326 Query: 434 -AKPAIIALQIVRGNESIYL 452 + + + + R N+ + L Sbjct: 327 LRVGSTVKIIVERDNKPLTL 346 >4YO1-A nrPDB Length = 351 Score = 372 bits (954), Expect = e-103, Method: Composition-based stats. Identities = 153/342 (44%), Positives = 221/342 (64%), Gaps = 11/342 (3%) Query: 31 GQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQ----GQKIPEEFKKFFGDDLPDQPAQ 86 G D +PSLAP+L+ +PA+V+V V+G G ++ + + + Sbjct: 11 GSAQDLTNMPSLAPVLKNAMPAIVNVAVQGYLPNNMASGNADDDDGENSKQPSRIPEKGR 70 Query: 87 PFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ 146 FE +GSGVII+ G ++TN+HVI A I++ L DGR A+LIG D ++D+A+L+I Sbjct: 71 KFESIGSGVIIDPKNGIIITNDHVIRNANLITVTLQDGRRLKARLIGGDSETDLAVLKID 130 Query: 147 NPSKLTQIAIADSDKLRVGDFAVAVGNPFGLG-----QTATSGIVSALGRSGLNLEGLEN 201 L + I DSDKL VGD+ VA+GNPFGL Q+AT GIVSAL RS LN+EG+EN Sbjct: 131 A-KNLKSLVIGDSDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVEN 189 Query: 202 FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDF 261 FIQTDA+IN GN+GGAL+N GELIGINTAI++P GG+VGIGFAIP NMA+ +AQQ+I F Sbjct: 190 FIQTDAAINPGNAGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAKDVAQQIIKF 249 Query: 262 GEIKRGLLGIKGTEMSADIAKAFN-LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGK 320 G I RGL+GI ++ ++A++ + +GA VS+V S + AG+K+GD+I +N Sbjct: 250 GSIHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDT 309 Query: 321 PLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTST 362 + ++++ I+ G+ K+ +LR+ KPL ++V + Sbjct: 310 KITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIK 351 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 375 LEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLA- 433 L + +G + +V + SPA AGL+ DVI+ +N ++ +++ ++ Sbjct: 264 LTPELAQSMGYAEDFQGALVSQVNQNSPAQLAGLKSGDVIVQINDTKITQATQVKTTISL 323 Query: 434 -AKPAIIALQIVRGNESIYL 452 + ++I+R N+ + L Sbjct: 324 LRAGSTAKIKILRDNKPLTL 343 >5Y28-A nrPDB Length = 357 Score = 341 bits (874), Expect = 4e-94, Method: Composition-based stats. Identities = 139/349 (39%), Positives = 209/349 (59%), Gaps = 14/349 (4%) Query: 24 QAVASIPGQVADQAPLPSLA---PMLEKVLPAVVSVRVEGTASQ-----GQKIPEEFKKF 75 Q++ + +V+ + ++ ++ + AVV++ E G F++F Sbjct: 13 QSMPKVKERVSVPSKDDTIYSYHDSIKDSIKAVVNISTEKKIKNNFIGGGVFNDPFFQQF 72 Query: 76 FGDDLPDQPAQPFE-GLGSGVIINASKGYVLTNNHVINQAQKISIQL-NDGREFDAKLIG 133 FGD P + E LGSGVII+ GY++TNNHVI+ A KI + + +E+ A L+G Sbjct: 73 FGDLGGMIPKERMERALGSGVIIS-KDGYIVTNNHVIDGADKIKVTIPGSNKEYSATLVG 131 Query: 134 SDDQSDIALLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSG 193 +D +SD+A+++I L I +DS+ + VGD A+GNPFG+G++ T GIVSAL +SG Sbjct: 132 TDSESDLAVIRI-TKDNLPTIKFSDSNDISVGDLVFAIGNPFGVGESVTQGIVSALNKSG 190 Query: 194 LNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMART 253 + + ENFIQTDASIN GNSGGAL++ G L+GINTAI++ GG+ GIGFAIPSNM + Sbjct: 191 IGINSYENFIQTDASINPGNSGGALIDSRGGLVGINTAIISKTGGNHGIGFAIPSNMVKD 250 Query: 254 LAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDI 313 QLI G+I+RG LG+ ++S D+ ++ D + GA V V S + KAG+ D+ Sbjct: 251 TVTQLIKTGKIERGYLGVGLQDLSGDLQNSY--DNKEGAVVISVEKDSPAKKAGILVWDL 308 Query: 314 ITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTST 362 IT +NGK + + ELR+ I + P +V L ++R+ K +TL Sbjct: 309 ITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAERK 357 Score = 34.7 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 16/48 (33%), Positives = 27/48 (56%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAA 434 D +G + V K SPA +AG+ D+I VN +V + E+R ++ + Sbjct: 282 DNKEGAVVISVEKDSPAKKAGILVWDLITEVNGKKVKNTNELRNLIGS 329 >3STI-A nrPDB Length = 245 Score = 334 bits (855), Expect = 7e-92, Method: Composition-based stats. Identities = 237/237 (100%), Positives = 237/237 (100%) Query: 28 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 87 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP Sbjct: 1 SIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQP 60 Query: 88 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN Sbjct: 61 FEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 120 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA Sbjct: 121 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 180 Query: 208 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI 264 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI Sbjct: 181 SINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEI 237 >3GCO-A nrPDB Length = 340 Score = 322 bits (826), Expect = 2e-88, Method: Composition-based stats. Identities = 128/320 (40%), Positives = 183/320 (57%), Gaps = 21/320 (6%) Query: 46 LEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVL 105 + + PAVV+V G + E LGSGVI++ +GY++ Sbjct: 36 VRRAAPAVVNVYNRGLNTNSHNQLE-----------------IRTLGSGVIMD-QRGYII 77 Query: 106 TNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVG 165 TN HVIN A +I + L DGR F+A L+GSD +D+A+L+I L I I +G Sbjct: 78 TNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIG 137 Query: 166 DFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGEL 225 D +A+GNP+ LGQT T GI+SA GR GLN G +NF+QTDASIN GNSGGAL+N GEL Sbjct: 138 DVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINPGNSGGALVNSLGEL 197 Query: 226 IGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAK 282 +GINT G GIGFAIP +A + +LI G + RG +GI G E++ A+ Sbjct: 198 MGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIRGYIGIGGREIAPLHAQ 257 Query: 283 AFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVK 342 +D +G V+EV P +A AG++ D+I S++ KP S E +++A PG+ + Sbjct: 258 GGGIDQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMAQVAEIRPGSVIP 317 Query: 343 LGLLRNGKPLEVEVTLDTST 362 + ++R+ K L ++VT+ Sbjct: 318 VVVMRDDKQLTLQVTIQEYP 337 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 22/70 (31%), Positives = 44/70 (62%), Gaps = 2/70 (2%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGV-NRDRVNSIAEMRKVLAAKP-AIIALQIV 444 D +GI ++EV PAA AG+Q +D+II V N+ ++++ M +V +P ++I + ++ Sbjct: 262 DQLQGIVVNEVSPDGPAANAGIQVNDLIISVDNKPAISALETMAQVAEIRPGSVIPVVVM 321 Query: 445 RGNESIYLLM 454 R ++ + L + Sbjct: 322 RDDKQLTLQV 331 >5JD8-A nrPDB Length = 334 Score = 306 bits (783), Expect = 2e-83, Method: Composition-based stats. Identities = 129/323 (39%), Positives = 184/323 (56%), Gaps = 23/323 (7%) Query: 46 LEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVL 105 + + PAVV+V ++ Q LGSGVI++ KGY+L Sbjct: 24 VRRAAPAVVNVYNRSLSAT------------------QQGLAIRTLGSGVIMS-DKGYIL 64 Query: 106 TNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVG 165 TN HVIN A++I + + +GR +A L+GSD+ +D+A+L+I L I I + +G Sbjct: 65 TNKHVINDAEQIIVAMQNGRISEALLVGSDNLTDLAVLKIDAT-NLPVIPININRTPHIG 123 Query: 166 DFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGEL 225 D +A+GNP+ LGQT T GI+SA GR GL+ G +NF+QTDASIN+GNSGGAL+N GEL Sbjct: 124 DVVLAIGNPYNLGQTVTQGIISATGRIGLSSSGRQNFLQTDASINQGNSGGALVNTLGEL 183 Query: 226 IGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAK 282 +GINT G GIGFAIP+ +A + ++LI G + RG +GI G E A Sbjct: 184 MGINTLSFDKSNNGETPEGIGFAIPTALATKVMEKLIRDGRVIRGYIGITGEEYPPFNAN 243 Query: 283 AFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVK 342 D G V +V P +A+AG+ GDII ++N KP S E ++A PGT + Sbjct: 244 DNGSDRVHGIKVKKVSPDGPAAQAGIHVGDIILNVNNKPATSVIETMDQVAEVRPGTTIP 303 Query: 343 LGLLRNGKPLEVEVTLDTSTSSS 365 + LLRNG+ + V++T+ + Sbjct: 304 VLLLRNGQQIAVQITITELDQNE 326 Score = 41.7 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 20/52 (38%), Positives = 27/52 (51%), Gaps = 1/52 (1%) Query: 386 KDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNS-IAEMRKVLAAKP 436 D GIK+ +V PAAQAG+ D+I+ VN S I M +V +P Sbjct: 247 SDRVHGIKVKKVSPDGPAAQAGIHVGDIILNVNNKPATSVIETMDQVAEVRP 298 >5T69-A nrPDB Length = 367 Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats. Identities = 126/348 (36%), Positives = 189/348 (54%), Gaps = 25/348 (7%) Query: 25 AVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQ---GQKIPEEFKKFFGDDLP 81 A AS+P +A + + PAVV + E ++ F++FFG P Sbjct: 19 AQASVP-----LTSESFVAAAVSRSGPAVVRIDTETVVTRRTDPILDDPFFQEFFGRSFP 73 Query: 82 DQPA-QPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDI 140 P + G GSG II+ S G +LTN HV++ A K+ + L DGR FD ++ G+D+ +D+ Sbjct: 74 VPPRERRIAGQGSGFIIDNS-GIILTNAHVVDGASKVVVTLRDGRTFDGQVRGTDEVTDL 132 Query: 141 ALLQIQNPSK-LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLN---L 196 A+++I+ L + S L+VGD+A+AVGNP GL T T GI+S LGRS Sbjct: 133 AVVKIEPQGSALPVAPLGTSSNLQVGDWAIAVGNPVGLDNTVTLGIISTLGRSAAQAGIP 192 Query: 197 EGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQ 256 + FIQTDA+IN GN+GG LLN GE+IGINTAI A + GIGFAIP + A+ + Sbjct: 193 DKRVEFIQTDAAINPGNAGGPLLNARGEVIGINTAIRA---DATGIGFAIPIDQAKAIQN 249 Query: 257 QLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQR--------GAFVSEVLPGSGSAKAGV 308 L G + +G++ ++ D A+ N + G V VLPG+ + +AG+ Sbjct: 250 TLAAGGTVPHPYIGVQMMNITVDQAQQNNRNPNSPFIIPEVDGILVMRVLPGTPAERAGI 309 Query: 309 KAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEV 356 + GD+I +++G P++ A L+ + +KL LLR + L + V Sbjct: 310 RRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLLRGDRRLSLTV 357 Score = 49.7 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 40/69 (57%), Gaps = 2/69 (2%) Query: 389 GKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKP--AIIALQIVRG 446 GI + V+ G+PA +AG+++ DVI+ V+ ++ A +++++ + L ++RG Sbjct: 290 VDGILVMRVLPGTPAERAGIRRGDVIVAVDGTPISDGARLQRIVEQAGLNKALKLDLLRG 349 Query: 447 NESIYLLMR 455 + + L ++ Sbjct: 350 DRRLSLTVQ 358 >3QO6-A nrPDB Length = 348 Score = 296 bits (757), Expect = 2e-80, Method: Composition-based stats. Identities = 117/358 (32%), Positives = 185/358 (51%), Gaps = 37/358 (10%) Query: 26 VASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPA 85 V S P ++ Q + + ++ P+VV + + Sbjct: 5 VVSTPKKL--QTDELATVRLFQENTPSVVYITNLAVRQDAFTLDVL-------------- 48 Query: 86 QPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQI 145 + +G GSG + + +G+++TN HVI A + + L D FDAK++G D D+A+L+I Sbjct: 49 EVPQGSGSGFVWD-KQGHIVTNYHVIRGASDLRVTLADQTTFDAKVVGFDQDKDVAVLRI 107 Query: 146 QNPS-KLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR---SGLNLEGLEN 201 P KL I + S L VG A+GNPFGL T T+G++S L R S +++ Sbjct: 108 DAPKNKLRPIPVGVSADLLVGQKVFAIGNPFGLDHTLTTGVISGLRREISSAATGRPIQD 167 Query: 202 FIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDF 261 IQTDA+IN GNSGG LL+ +G LIGINTAI +P G S G+GF+IP + + QL+ F Sbjct: 168 VIQTDAAINPGNSGGPLLDSSGTLIGINTAIYSPSGASSGVGFSIPVDTVGGIVDQLVRF 227 Query: 262 GEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKA----------- 310 G++ R +LGI + + D ++ G V + P + KAG+++ Sbjct: 228 GKVTRPILGI---KFAPD--QSVEQLGVSGVLVLDAPPSGPAGKAGLQSTKRDGYGRLVL 282 Query: 311 GDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASA 368 GDIITS+NG +++ ++L + + G +V + +LR ++ VTL+ SA+A Sbjct: 283 GDIITSVNGTKVSNGSDLYRILDQCKVGDEVTVEVLRGDHKEKISVTLEPKPDESAAA 340 >3NUM-A nrPDB Length = 332 Score = 291 bits (745), Expect = 4e-79, Method: Composition-based stats. Identities = 105/334 (31%), Positives = 175/334 (52%), Gaps = 41/334 (12%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK+ PAVV + E F+K LP + GSG I++ Sbjct: 16 IADVVEKIAPAVVHI-------------ELFRK-----LPFSKREVPVASGSGFIVS-ED 56 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK 161 G ++TN HV+ ++ ++L +G ++AK+ D+++DIAL++I + KL + + S + Sbjct: 57 GLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE 116 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNL---EGLENFIQTDASINRGNSGGAL 218 LR G+F VA+G+PF L T T+GIVS R G L ++IQTDA IN GN+GG L Sbjct: 117 LRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNAGGPL 176 Query: 219 LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGE-----IKRGLLGIKG 273 +NL+GE+IGINT + + GI FAIPS+ + + D K+ +GI+ Sbjct: 177 VNLDGEVIGINTLKV-----TAGISFAIPSDKIKKFLTESHDRQAKGKAITKKKYIGIRM 231 Query: 274 TEMSADIAKAFN------LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE 327 +++ AK DV GA++ EV+P + + G+K D+I S+NG+ + S + Sbjct: 232 MSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGGLKENDVIISINGQSVVSAND 291 Query: 328 LRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTS 361 + I + + + + R + + + V + Sbjct: 292 VSDVIKRE---STLNMVVRRGNEDIMITVIPEEI 322 Score = 47.8 bits (112), Expect = 1e-05, Method: Composition-based stats. Identities = 46/227 (20%), Positives = 90/227 (39%), Gaps = 31/227 (13%) Query: 233 LAPGGGSVGIG--FAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQR 290 L PG V IG F++ + + + G+ LG++ ++M +Q Sbjct: 117 LRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGK----ELGLRNSDM---------DYIQT 163 Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPL-NSFAELRSRIATTEPGTKVKLGLLRNG 349 A ++ G + +L+G+ + + ++ + I+ P K+K L Sbjct: 164 DAIINYGNAGGP-----------LVNLDGEVIGINTLKVTAGISFAIPSDKIK-KFLTES 211 Query: 350 KPLEVEVTLDTSTSSSASAEMITPALEGATL--SDGQLKDGGKGIKIDEVVKGSPAAQAG 407 + + T M + + L D G I EV+ +PA G Sbjct: 212 HDRQAKGKAITKKKYIGIRMMSLTSSKAKELKDRHRDFPDVISGAYIIEVIPDTPAEAGG 271 Query: 408 LQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRGNESIYLLM 454 L+++DVII +N V S ++ V+ + + + + + RGNE I + + Sbjct: 272 LKENDVIISINGQSVVSANDVSDVIK-RESTLNMVVRRGNEDIMITV 317 >4RI0-A nrPDB Length = 332 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 108/335 (32%), Positives = 171/335 (51%), Gaps = 44/335 (13%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK+ PAVV + + FG ++P GSG I++ + Sbjct: 14 IADVVEKIAPAVVHIELF-----------LRHPLFGRNVPL-------SSGSGFIMSEA- 54 Query: 102 GYVLTNNHVIN------QAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIA 155 G ++TN HV++ Q++ +QL +G ++A + D +SDIA ++I KL + Sbjct: 55 GLIITNAHVVSSNSAAPGRQQLKVQLQNGDSYEATIKDIDKKSDIATIKIHPKKKLPVLL 114 Query: 156 IADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNL---EGLENFIQTDASINRG 212 + S LR G+F VA+G+PF L T T+GIVS R G L + ++IQTDA IN G Sbjct: 115 LGHSADLRPGEFVVAIGSPFALQNTVTTGIVSTAQREGRELGLRDSDMDYIQTDAIINYG 174 Query: 213 NSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLID--FGEIKRGLLG 270 N+GG L+NL+GE+IGINT + + GI FAIPS+ + D + K+ +G Sbjct: 175 NAGGPLVNLDGEVIGINTLKV-----TAGISFAIPSDRITRFLTEFQDKQIKDWKKRFIG 229 Query: 271 IKGTEMSADIAKAFN------LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS 324 I+ ++ + +V G +V EV P S S + G++ GDII +NG+PL Sbjct: 230 IRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVD 289 Query: 325 FAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLD 359 +EL+ + T P + L + R L + + Sbjct: 290 SSELQEAVLTESP---LLLEVRRGNDDLLFSIAPE 321 Score = 54.7 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 22/86 (25%), Positives = 45/86 (52%), Gaps = 2/86 (2%) Query: 366 ASAEMITPAL-EGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNS 424 ITP+L + S+ + GI + EV SP+ + G+Q D+I+ VN + Sbjct: 230 IRMRTITPSLVDELKASNPDFPEVSSGIYVQEVAPNSPSQRGGIQDGDIIVKVNGRPLVD 289 Query: 425 IAEMRKVLAAKPAIIALQIVRGNESI 450 +E+++ + + + + L++ RGN+ + Sbjct: 290 SSELQEAVLTE-SPLLLEVRRGNDDL 314 >4IC6-A nrPDB Length = 368 Score = 269 bits (688), Expect = 1e-72, Method: Composition-based stats. Identities = 126/364 (34%), Positives = 188/364 (51%), Gaps = 47/364 (12%) Query: 39 LPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKK-------FFGDDLPDQPA-----Q 86 PS+A + E V P V +I + F+K F L Q + Sbjct: 5 DPSVATV-EDVSPTV--FPAGPLFPTEGRIVQLFEKNTYSVVNIFDVTLRPQLKMTGVVE 61 Query: 87 PFEGLGSGVIINASKGYVLTNNHVINQA-----------QKISIQLNDG--REFDAKLIG 133 EG GSGV+ + +GY++TN HVI A +++I +DG + F+ KL+G Sbjct: 62 IPEGNGSGVVWDG-QGYIVTNYHVIGNALSRNPSPGDVVGRVNILASDGVQKNFEGKLVG 120 Query: 134 SDDQSDIALLQIQNPSKL-TQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRS 192 +D D+A+L++ P L I + S+ L+VG +A+GNPFG T T G++S L R Sbjct: 121 ADRAKDLAVLKVDAPETLLKPIKVGQSNSLKVGQQCLAIGNPFGFDHTLTVGVISGLNRD 180 Query: 193 GLNLEGLE--NFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNM 250 + G+ IQTDA+IN GN+GG LL+ G LIGINTAI G S G+GFAIPS+ Sbjct: 181 IFSQTGVTIGGGIQTDAAINPGNAGGPLLDSKGNLIGINTAIFTQTGTSAGVGFAIPSST 240 Query: 251 ARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKA 310 + QLI F ++ R + I E++ D A L+V+ GA V +V S + KAG+ Sbjct: 241 VLKIVPQLIQFSKVLRAGINI---ELAPD-PVANQLNVRNGALVLQVPGKSLAEKAGLHP 296 Query: 311 -----------GDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLD 359 GDII +++ KP+ + AEL + G KV L + R + LE++++L+ Sbjct: 297 TSRGFAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGDKVTLKIKRGNEDLELKISLE 356 Query: 360 TSTS 363 +S Sbjct: 357 EKSS 360 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 35/77 (45%), Gaps = 13/77 (16%) Query: 391 GIKIDEVVKGSPAAQAGLQK-----------DDVIIGVNRDRVNSIAEMRKVLAAK--PA 437 G + +V S A +AGL D+I+ V+ V + AE+ K+L Sbjct: 277 GALVLQVPGKSLAEKAGLHPTSRGFAGNIVLGDIIVAVDDKPVKNKAELMKILDEYSVGD 336 Query: 438 IIALQIVRGNESIYLLM 454 + L+I RGNE + L + Sbjct: 337 KVTLKIKRGNEDLELKI 353 >1L1J-A nrPDB Length = 239 Score = 268 bits (686), Expect = 3e-72, Method: Composition-based stats. Identities = 94/237 (39%), Positives = 145/237 (61%), Gaps = 10/237 (4%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIP---EEFKKFFGDDLPDQPAQPFEGLGSGVIIN 98 + ++E PAVV + V T P + FKK+FG+ LP + LGSG I + Sbjct: 6 IVNVVEACAPAVVKIDVVKTVKTSFFDPYFEQFFKKWFGE-LPPGFERQVASLGSGFIFD 64 Query: 99 ASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ-NPSKLTQIAIA 157 +GY+LTN HV+ A I++ + DG ++DA+ IG D++ DIA+++I+ + K + Sbjct: 65 P-EGYILTNYHVVGGADNITVTMLDGSKYDAEYIGGDEELDIAVIKIKASDKKFPYLEFG 123 Query: 158 DSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENF---IQTDASINRGNS 214 DSDK+++G++A+A+GNP G T T G+VSA R +G + IQTDA+IN GNS Sbjct: 124 DSDKVKIGEWAIAIGNPLGFQHTVTVGVVSATNRRIPKPDGSGYYVGLIQTDAAINPGNS 183 Query: 215 GGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGI 271 GG LLN++GE+IGINTAI+ P +V +GFAIP N + ++ ++++ LG+ Sbjct: 184 GGPLLNIHGEVIGINTAIVNP-QEAVNLGFAIPINTVKKFLDTILTQKKVEKAYLGV 239 >6IEO-A nrPDB Length = 314 Score = 267 bits (682), Expect = 8e-72, Method: Composition-based stats. Identities = 106/284 (37%), Positives = 159/284 (55%), Gaps = 21/284 (7%) Query: 92 GSGVIINASKGYVLTNNHVINQAQ------KISIQLNDGREFDAKLIGSDDQSDIALLQI 145 GSGVI++ +GY++TNNHVI++A K ++ NDG+E A L+G D ++D+A+L++ Sbjct: 32 GSGVIVDG-RGYIVTNNHVISEAANNPSQFKTTVVFNDGKEVPANLVGRDPKTDLAVLKV 90 Query: 146 QNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR------SGLNLEGL 199 N LT + DS K+RVGD +AVG P GL T T GIVSAL R G + + + Sbjct: 91 DNVDNLTVARLGDSSKVRVGDEVLAVGAPLGLRSTVTQGIVSALHRPVPLSGEGSDTDTV 150 Query: 200 ENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLI 259 + IQTDASIN GNSGG L++++ ++IGINTA + + G+GFAIP N + +A LI Sbjct: 151 IDAIQTDASINHGNSGGPLIDMDAQVIGINTAGKSLSDSASGLGFAIPVNEMKLVANSLI 210 Query: 260 DFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNG 319 G+I LGI +S IA GA V+ V GS + K G+ D+I + Sbjct: 211 KDGKIVHPTLGISTRSVSNAIA--------SGAQVANVKAGSPAQKGGILENDVIVKVGN 262 Query: 320 KPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTS 363 + + E + G + ++R G+ + + V D ++ Sbjct: 263 RAVADSDEFVVAVRQLAIGQDAPIEVVREGRHVTLTVKPDPDST 306 Score = 33.2 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 31/67 (46%), Gaps = 2/67 (2%) Query: 391 GIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLA--AKPAIIALQIVRGNE 448 G ++ V GSPA + G+ ++DVI+ V V E + A +++VR Sbjct: 234 GAQVANVKAGSPAQKGGILENDVIVKVGNRAVADSDEFVVAVRQLAIGQDAPIEVVREGR 293 Query: 449 SIYLLMR 455 + L ++ Sbjct: 294 HVTLTVK 300 >4FLN-A nrPDB Length = 539 Score = 264 bits (675), Expect = 5e-71, Method: Composition-based stats. Identities = 77/299 (25%), Positives = 128/299 (42%), Gaps = 22/299 (7%) Query: 79 DLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLIGSDDQ 137 LP Q + F GS +I G +LTN H + ++ ++ D R++ AK++ Sbjct: 63 SLPWQKQRQFTSTGSAFMIG--DGKLLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVD 120 Query: 138 SDIALLQIQNPSKLTQI-AIADSDKLRVGDFAVAVGNPFGLGQ-TATSGIVSALGRSGLN 195 DIALL +++ + R+ D VG P G + T G+VS + + Sbjct: 121 CDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLGGDTISVTKGVVSRIEVTSY- 179 Query: 196 LEGLENF--IQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMART 253 G + IQ DA+IN GNSGG N GE IG+ + + IG+ IP+ + Sbjct: 180 AHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGVAFQVYR-SEETENIGYVIPTTVVSH 238 Query: 254 LAQQLIDFGE-IKRGLLGIKGTEM-SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAG 311 G+ LG+ ++ + + + + G V V P S ++K +K G Sbjct: 239 FLTDYERNGKYTGYPCLGVLLQKLENPALRECLKVPTNEGVLVRRVEPTSDASKV-LKEG 297 Query: 312 DIITSLNG--------KPLNSFAEL--RSRIATTEPGTKVKLGLLRNGKPLEVEVTLDT 360 D+I S + P S + R I+ G ++G++R G+ +V+V L Sbjct: 298 DVIVSFDDLHVGCEGTVPFRSSERIAFRYLISQKFAGDIAEIGIIRAGEHKKVQVVLRP 356 >5ILB-A nrPDB Length = 474 Score = 258 bits (659), Expect = 4e-69, Method: Composition-based stats. Identities = 77/298 (25%), Positives = 129/298 (43%), Gaps = 23/298 (7%) Query: 79 DLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLIGSDDQ 137 LP Q + F GS +I G +LTN H + ++ ++ D R++ AK++ Sbjct: 23 SLPWQKQRQFTSTGSAFMIG--DGKLLTNAHCVEHDTQVKVKRRGDDRKYVAKVLVRGVD 80 Query: 138 SDIALLQIQNPSKLTQI-AIADSDKLRVGDFAVAVGNPFGLGQ-TATSGIVSALGRSGLN 195 DIALL +++ + R+ D VG P G + T G+VS + + Sbjct: 81 CDIALLSVESEDFWKGAEPLRLGHLPRLQDSVTVVGYPLGGDTISVTKGVVSRIEVTSY- 139 Query: 196 LEGLENF--IQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMART 253 G + IQ DA+IN GNSGG N GE IG+ + + IG+ IP+ + Sbjct: 140 AHGSSDLLGIQIDAAINPGNSGGPAFNDQGECIGVAFQVYR-SEETENIGYVIPTTVVSH 198 Query: 254 LAQQLIDFGE-IKRGLLGIKGTEM-SADIAKAFNLD-VQRGAFVSEVLPGSGSAKAGVKA 310 G+ +LGI+ +M + D+ K+ ++ Q+G + + P + ++ +K Sbjct: 199 FLTDYERNGKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRIRRIEPTAPESQV-LKP 257 Query: 311 GDIITSLNG--------KPLNSFAEL--RSRIATTEPGTKVKLGLLRNGKPLEVEVTL 358 DII S +G P + I+ G + +LRN + LE + L Sbjct: 258 SDIILSFDGVNIANDGTVPFRHGERIGFSYLISQKYTGDSALVKVLRNKEILEFNIKL 315 >5M3O-A nrPDB Length = 334 Score = 253 bits (647), Expect = 9e-68, Method: Composition-based stats. Identities = 98/333 (29%), Positives = 170/333 (51%), Gaps = 42/333 (12%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK PAVV + + + F G ++P GSG ++ A+ Sbjct: 18 IADVVEKTAPAVVYIEIL-----------DRHPFLGREVPI-------SNGSGFVV-AAD 58 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK 161 G ++TN HV+ +++ ++L G ++A + D +DIA L+IQ L + + S Sbjct: 59 GLIVTNAHVVADRRRVRVRLLSGDTYEAVVTAVDPVADIATLRIQTKEPLPTLPLGRSAD 118 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNL---EGLENFIQTDASINRGNSGGAL 218 +R G+F VA+G+PF L T TSGIVS+ R +L + +IQTDA+I+ GNSGG L Sbjct: 119 VRQGEFVVAMGSPFALQNTITSGIVSSAQRPARDLGLPQTNVEYIQTDAAIDFGNSGGPL 178 Query: 219 LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGE------IKRGLLGIK 272 +NL+GE+IG+NT + + GI FAIPS+ R + +R +G+ Sbjct: 179 VNLDGEVIGVNTMKV-----TAGISFAIPSDRLREFLHRGEKKNSSSGISGSQRRYIGVM 233 Query: 273 GTEMSADIAKAFN------LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFA 326 +S I DVQ G + +V+ GS + +AG++ GD+I ++ + + + Sbjct: 234 MLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNAE 293 Query: 327 ELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLD 359 ++ + T +++ + + R + L + VT + Sbjct: 294 DVYEAVRTQ---SQLAVQIRRGRETLTLYVTPE 323 Score = 95.6 bits (236), Expect = 4e-20, Method: Composition-based stats. Identities = 34/149 (22%), Positives = 71/149 (47%), Gaps = 6/149 (4%) Query: 310 AGDIITSLNGKPL-NSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASA 368 +G + +L+G+ + + ++ + I+ P +++ L G+ + S Sbjct: 174 SGGPLVNLDGEVIGVNTMKVTAGISFAIPSDRLR-EFLHRGEKKNSSSGISGSQRRYIGV 232 Query: 369 EMIT---PALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSI 425 M+T L L + D G+ I +V+ GSPA +AGL+ DVI+ + V + Sbjct: 233 MMLTLSPSILAELQLREPSFPDVQHGVLIHKVILGSPAHRAGLRPGDVILAIGEQMVQNA 292 Query: 426 AEMRKVLAAKPAIIALQIVRGNESIYLLM 454 ++ + + + + +A+QI RG E++ L + Sbjct: 293 EDVYEAVRTQ-SQLAVQIRRGRETLTLYV 320 >5JYK-A nrPDB Length = 566 Score = 251 bits (640), Expect = 5e-67, Method: Composition-based stats. Identities = 87/369 (23%), Positives = 149/369 (40%), Gaps = 56/369 (15%) Query: 14 SVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFK 73 S G+ +S + +++ + P +PS + AVV V T Sbjct: 71 SNGMIVSTTTESIPAAPSWETVVKVVPS--------MDAVVKVFCVHTEPNF-------- 114 Query: 74 KFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLI 132 LP Q + + SG II + VLTN H + ++ ++ ++ A ++ Sbjct: 115 -----SLPWQRKRQYSSGSSGFIIGGRR--VLTNAHSVEHHTQVKLKKRGSDTKYLATVL 167 Query: 133 GSDDQSDIALLQIQNPSKLTQI-AIADSDKLRVGDFAVAVGNPFGLGQ-TATSGIVSALG 190 + DIALL + + + + D + D VG P G + TSG+VS + Sbjct: 168 AIGTECDIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGYPIGGDTISVTSGVVSRME 227 Query: 191 -----RSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFA 245 L G +Q DA+IN GNSGG N G+ +GI L IG+ Sbjct: 228 ILSYVHGSTELLG----LQIDAAINSGNSGGPAFNDKGKCVGIAFQSLKHEDA-ENIGYV 282 Query: 246 IPSNMARTLAQQLIDFGEIKR----GLLGIKGTEM-SADIAKAFNLD-VQRGAFVSEVLP 299 IP+ + Q D+ + + +LGI+ +M + D+ K+ ++ Q+G + + P Sbjct: 283 IPTPVIVHFIQ---DYEKHDKYTGFPVLGIEWQKMENPDLRKSMGMESHQKGVRIRRIEP 339 Query: 300 GSGSAKAGVKAGDIITSLNG--------KPLNSFAEL--RSRIATTEPGTKVKLGLLRNG 349 + ++ +K DII S +G P + I+ G + +LRN Sbjct: 340 TAPESQV-LKPSDIILSFDGVNIANDGTVPFRHGERIGFSYLISQKYTGDSALVKVLRNK 398 Query: 350 KPLEVEVTL 358 + LE + L Sbjct: 399 EILEFNIKL 407 >3TJO-A nrPDB Length = 231 Score = 231 bits (590), Expect = 4e-61, Method: Composition-based stats. Identities = 82/223 (36%), Positives = 126/223 (56%), Gaps = 27/223 (12%) Query: 42 LAPMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASK 101 +A ++EK+ PAVV + E F+K LP + GSG I++ Sbjct: 33 IADVVEKIAPAVVHI-------------ELFRK-----LPFSKREVPVASGSGFIVS-ED 73 Query: 102 GYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDK 161 G ++TN HV+ ++ ++L +G ++AK+ D+++DIAL++I + KL + + S + Sbjct: 74 GLIVTNAHVVTNKHRVKVELKNGATYEAKIKDVDEKADIALIKIDHQGKLPVLLLGRSSE 133 Query: 162 LRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNL---EGLENFIQTDASINRGNSGGAL 218 LR G+F VA+G+PF L T T+GIVS R G L ++IQTDA IN GN+GG L Sbjct: 134 LRPGEFVVAIGSPFSLQNTVTTGIVSTTQRGGKELGLRNSDMDYIQTDAIINYGNAGGPL 193 Query: 219 LNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDF 261 +NL+GE+IGINT + + GI FAIPS+ + + D Sbjct: 194 VNLDGEVIGINTLKV-----TAGISFAIPSDKIKKFLTESHDR 231 >2QF3-A nrPDB Length = 243 Score = 230 bits (587), Expect = 8e-61, Method: Composition-based stats. Identities = 98/224 (43%), Positives = 128/224 (57%), Gaps = 21/224 (9%) Query: 46 LEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVL 105 + + PAVV+V G + E LGSGVI++ +GY++ Sbjct: 38 VRRAAPAVVNVYNRGLNTNSHNQLE-----------------IRTLGSGVIMD-QRGYII 79 Query: 106 TNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVG 165 TN HVIN A +I + L DGR F+A L+GSD +D+A+L+I L I I +G Sbjct: 80 TNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIG 139 Query: 166 DFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGEL 225 D +A+GNP+ LGQT T GI+SA GR GLN G +NF+QTDASIN GNSGGAL+N GEL Sbjct: 140 DVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGEL 199 Query: 226 IGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFGEIKR 266 +GINT G GIGFAIP +A + +LI G + R Sbjct: 200 MGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDGRVIR 243 >2R3U-A nrPDB Length = 211 Score = 226 bits (575), Expect = 2e-59, Method: Composition-based stats. Identities = 97/220 (44%), Positives = 126/220 (57%), Gaps = 21/220 (9%) Query: 46 LEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVL 105 + + PAVV+V G + E LGSGVI++ +GY++ Sbjct: 10 VRRAAPAVVNVYNRGLNTNSHNQLE-----------------IRTLGSGVIMD-QRGYII 51 Query: 106 TNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQIAIADSDKLRVG 165 TN HVIN A +I + L DGR F+A L+GSD +D+A+L+I L I I +G Sbjct: 52 TNKHVINDADQIIVALQDGRVFEALLVGSDSLTDLAVLKINATGGLPTIPINARRVPHIG 111 Query: 166 DFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGEL 225 D +A+GNP+ LGQT T GI+SA GR GLN G +NF+QTDASIN GNSGGAL+N GEL Sbjct: 112 DVVLAIGNPYNLGQTITQGIISATGRIGLNPTGRQNFLQTDASINHGNSGGALVNSLGEL 171 Query: 226 IGINTAILAP---GGGSVGIGFAIPSNMARTLAQQLIDFG 262 +GINT G GIGFAIP +A + +LI G Sbjct: 172 MGINTLSFDKSNDGETPEGIGFAIPFQLATKIMDKLIRDG 211 >2Z9I-A nrPDB Length = 324 Score = 218 bits (555), Expect = 4e-57, Method: Composition-based stats. Identities = 112/290 (38%), Positives = 165/290 (56%), Gaps = 34/290 (11%) Query: 92 GSGVIINASKGYVLTNNHVINQA---------QKISIQLNDGREFDAKLIGSDDQSDIAL 142 GSG+I++A +G +LTNNHVI A K ++ +DGR ++G+D SDIA+ Sbjct: 33 GSGIILSA-EGLILTNNHVIAAAAKPPLGSPPPKTTVTFSDGRTAPFTVVGADPTSDIAV 91 Query: 143 LQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR------SGLNL 196 +++Q S LT I++ S LRVG +A+G+P GL T T+GIVSAL R N Sbjct: 92 VRVQGVSGLTPISLGSSSDLRVGQPVLAIGSPLGLEGTVTTGIVSALNRPVSTTGEAGNQ 151 Query: 197 EGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGG-------GSVGIGFAIPSN 249 + + IQTDA+IN GNSGGAL+N+N +L+G+N+AI G GS+G+GFAIP + Sbjct: 152 NTVLDAIQTDAAINPGNSGGALVNMNAQLVGVNSAIATLGADSADAQSGSIGLGFAIPVD 211 Query: 250 MARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVK 309 A+ +A +LI G+ LG++ T N GA + EV+ G +A AGV Sbjct: 212 QAKRIADELISTGKASHASLGVQVT----------NDKDTLGAKIVEVVAGGAAANAGVP 261 Query: 310 AGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR-NGKPLEVEVTL 358 G ++T ++ +P+NS L + + + PG V L +G V+VTL Sbjct: 262 KGVVVTKVDDRPINSADALVAAVRSKAPGATVALTFQDPSGGSRTVQVTL 311 >4IC5-A nrPDB Length = 291 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 84/243 (34%), Positives = 119/243 (48%), Gaps = 27/243 (11%) Query: 43 APMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINASKG 102 + +K P+VV + E K GD L D+ EG GSG + + G Sbjct: 43 VNLFQKTSPSVVYIEAI----------ELPKTSSGDILTDEENGKIEGTGSGFVWD-KLG 91 Query: 103 YVLTNNHVIN---------QAQKISIQLNDGREF--DAKLIGSDDQSDIALLQIQNPSK- 150 +++TN HVI Q K+S+ G F + K++G D +D+A+L+I+ + Sbjct: 92 HIVTNYHVIAKLATDQFGLQRCKVSLVDAKGTRFSKEGKIVGLDPDNDLAVLKIETEGRE 151 Query: 151 LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEG--LENFIQTDAS 208 L + + S+ LRVG A+GNP+G T T G+VS LGR + G + IQTDA Sbjct: 152 LNPVVLGTSNDLRVGQSCFAIGNPYGYENTLTIGVVSGLGREIPSPNGKSISEAIQTDAD 211 Query: 209 INRGNSGGALLNLNGELIGINTAILAPGGG--SVGIGFAIPSNMARTLAQQLIDFGEIKR 266 IN GN+GG LL+ G IG+NTA G S G+ FAIP + LI +G R Sbjct: 212 INSGNAGGPLLDSYGHTIGVNTATFTRKGSGMSSGVNFAIPIDTVVRTVPYLIVYGTAYR 271 Query: 267 GLL 269 L Sbjct: 272 DRL 274 >5ILA-A nrPDB Length = 301 Score = 185 bits (469), Expect = 4e-47, Method: Composition-based stats. Identities = 63/262 (24%), Positives = 103/262 (39%), Gaps = 39/262 (14%) Query: 14 SVGLTLSASFQAVASIPGQVADQAPLPSLAPMLEKVLPAVVSVRVEGTASQGQKIPEEFK 73 S G+ +S + +++ + P +PS + AVV V T Sbjct: 71 SNGMIVSTTTESIPAAPSWETVVKVVPS--------MDAVVKVFCVHTEPNFS------- 115 Query: 74 KFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLN-DGREFDAKLI 132 LP Q + + SG II + VLTN H + ++ ++ ++ A ++ Sbjct: 116 ------LPWQRKRQYSSGSSGFIIGGRR--VLTNAHSVEHHTQVKLKKRGSDTKYLATVL 167 Query: 133 GSDDQSDIALLQIQNPSKLTQI-AIADSDKLRVGDFAVAVGNPFGLGQ-TATSGIVSALG 190 + DIALL + + + + D + D VG P G + TSG+VS + Sbjct: 168 AIGTECDIALLTVTDDEFWEGVSPVEFGDLPALQDAVTVVGYPIGGDTISVTSGVVSRME 227 Query: 191 -----RSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFA 245 L G +Q DA+IN GNSGG N G+ +GI L IG+ Sbjct: 228 ILSYVHGSTELLG----LQIDAAINSGNSGGPAFNDKGKCVGIAFQSLKHEDA-ENIGYV 282 Query: 246 IPSNMARTLAQQLIDFGEIKRG 267 IP+ + Q D+ + + Sbjct: 283 IPTPVIVHFIQ---DYEKHDKY 301 >5HM9-A nrPDB Length = 189 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 47/168 (27%), Positives = 81/168 (48%), Gaps = 7/168 (4%) Query: 93 SGVIINASKGYVLTNNHVINQAQKISIQLNDG---REFDAKLIGSDDQSDIALLQIQNPS 149 SG I+ + GYV+T H +++ +IS+Q+ R F A+++ + D+ALL++Q Sbjct: 24 SGAIVG-TNGYVITTLHSVSKLPEISVQVATTGGIRRFPAQVVKTIPGHDLALLKMQTTE 82 Query: 150 KLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIV-SALGRSGLNLEGLENFIQTDAS 208 K +AD + G A G G+V SA + + + +++DA Sbjct: 83 KFLHFRMADVQTVVPGQQVFAFGRNMAGAPLVRQGLVQSADAPLAVGATQITHLLRSDAV 142 Query: 209 INRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQ 256 + +GG L+N G+L+GIN A P G GF +P+ + + Q Sbjct: 143 YSWEQTGGPLVNAQGDLVGINIAATGPTGKVE--GFTVPAQVIVSHLQ 188 >3LT3-A nrPDB Length = 217 Score = 131 bits (329), Expect = 7e-31, Method: Composition-based stats. Identities = 59/234 (25%), Positives = 105/234 (44%), Gaps = 42/234 (17%) Query: 37 APLPSLA--PMLEKVLPAVVSVRVEGTASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSG 94 +P P+L P++ P+VV +R A + QK+ E G+G Sbjct: 6 SPDPALVNNPVVAATEPSVVKIR--SLAPRCQKVLE---------------------GTG 42 Query: 95 VIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPSKLTQI 154 +I+ + V+TN HV+ + +++ D + F+A ++ D D+A+L + + + Sbjct: 43 FVISPDR--VMTNAHVVAGSNNVTVYAGD-KPFEATVVSYDPSVDVAILAVPHLPPPPLV 99 Query: 155 AIADSDKLRVGDFAVAVGNPFGLGQTATSG-IVSALGRSGLNLEGLENFIQTD-----AS 208 A+ K G V +G P G TAT I A+ SG ++ G + D A Sbjct: 100 FAAEPAK--TGADVVVLGYPGGGNFTATPARIREAIRLSGPDIYGDPEPVTRDVYTIRAD 157 Query: 209 INRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFG 262 + +G++GG L++LNG+++G+ + GF + A +A QL G Sbjct: 158 VEQGDAGGPLIDLNGQVLGV---VFGAAIDDAETGFVL---TAGEVAGQLAKIG 205 >2KL1-A nrPDB Length = 94 Score = 84.8 bits (208), Expect = 8e-17, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 44/79 (55%), Gaps = 1/79 (1%) Query: 286 LDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGL 345 ++ +G +V VLP +A ++AGD I +++G+P+N+ ++ S + + G +V++ Sbjct: 1 MNEAKGVYVMSVLPNMPAA-GRLEAGDRIAAIDGQPINTSEQIVSYVREKQAGDRVRVTF 59 Query: 346 LRNGKPLEVEVTLDTSTSS 364 +R+ K E E+ L Sbjct: 60 IRDRKQHEAELVLKPFPHH 78 >1DUE-A nrPDB Length = 242 Score = 67.5 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 43/195 (22%), Positives = 81/195 (41%), Gaps = 35/195 (17%) Query: 89 EGLGSGVIINASKGYVLTNNHV----------INQAQKISIQLNDGRE-----FDAKLIG 133 + +GV+I K VLTN H+ ++ I+ N E ++ K I Sbjct: 54 QTSATGVLIG--KNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTETPYGEYEVKEIL 111 Query: 134 SDD---QSDIALLQIQNP-------SKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATS 183 + D+AL++++ K++ I S+ L+ GD +G PF Sbjct: 112 QEPFGAGVDLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLELIGYPFDHK----- 166 Query: 184 GIVSALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIG 243 V+ + RS + L L ++ GN+G + N NGEL+GI+++ ++ I Sbjct: 167 --VNQMHRSEIELTTLSRGLRYYGFTVPGNAGSGIFNSNGELVGIHSSKVSHLDREHQIN 224 Query: 244 FAIPS-NMARTLAQQ 257 + + N + + + Sbjct: 225 YGVGIGNYVKRIINE 239 >4INK-A nrPDB Length = 205 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 37/174 (21%), Positives = 62/174 (35%), Gaps = 25/174 (14%) Query: 90 GLGSGVIINASKGYVLTNNHV---------INQAQKISIQLNDGREFDAKLIGSDDQSDI 140 G G+G ++ ++TN HV I G K++ + DI Sbjct: 24 GAGTGFVVG--NHTIITNKHVTYHMKVGDEIKAHPNGFYNNGGGLYKVTKIVDYPGKEDI 81 Query: 141 ALLQIQNPSKLT--------QIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRS 192 A++Q++ S + + + + +G P G + Sbjct: 82 AVVQVEEKSTQPKGRKFKDFTSKFNIASEAKENEPISVIGYPNPNGNKLQM-----YEST 136 Query: 193 GLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAI 246 G L N + +DA + G+SG +LN E IG+ A P G S FA+ Sbjct: 137 GKVLSVNGNIVTSDAVVQPGSSGSPILNSKREAIGVMYASDKPTGESTR-SFAV 189 >2AS9-A nrPDB Length = 210 Score = 60.1 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 66/186 (35%), Gaps = 26/186 (13%) Query: 93 SGVIINASKGYVLTNNHVINQ---AQKISIQ----LNDGREFDAKLIGSDD-QSDIALLQ 144 +G +I K ++TN HV +I+ +G + K I DI+++ Sbjct: 26 TGFVIG--KNTIITNKHVSKDYKVGDRITAHPNGDKGNGGIYKIKSISDYPGDEDISVMN 83 Query: 145 IQNPS----------KLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGL 194 I+ + A + +V D +G P + +G Sbjct: 84 IEEQAVERGPKGFNFNENVQAFNFAKDAKVDDKIKVIGYPLPAQNSFKQ-----FESTGT 138 Query: 195 NLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTL 254 +N + DA I GNSG +LN N E+IG+ + G G + + Sbjct: 139 IKRIKDNILNFDAYIEPGNSGSPVLNSNNEVIGVVYGGIGKIGSEYN-GAVYFTPQIKDF 197 Query: 255 AQQLID 260 Q+ I+ Sbjct: 198 IQKHIE 203 >2KJP-A nrPDB Length = 91 Score = 59.8 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 35/79 (44%), Gaps = 1/79 (1%) Query: 290 RGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNG 349 G + S V+ + K ++ GD I S +GK S +L I++ + G KV L + R Sbjct: 1 NGIYASSVVENMPA-KGKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTLKIEREE 59 Query: 350 KPLEVEVTLDTSTSSSASA 368 K V +TL A Sbjct: 60 KEKRVTLTLKQFPDEPDRA 78 >2KJK-A nrPDB Length = 100 Score = 57.8 bits (138), Expect = 8e-09, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGK 350 G +V V +A + AGD+IT ++G+ S E I + + G VK+ K Sbjct: 8 GVYVLSVKEDVPAA-GILHAGDLITEIDGQSFKSSQEFIDYIHSKKVGDTVKIKYKHGNK 66 Query: 351 PLEVEVTLDTSTSS 364 E + L Sbjct: 67 NEEASIKLTAIDKK 80 >3I1E-A nrPDB Length = 90 Score = 57.8 bits (138), Expect = 9e-09, Method: Composition-based stats. Identities = 19/74 (25%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGK 350 G +V V +A + AGD+IT ++G+ S E I + + G VK+ K Sbjct: 3 GVYVLSVKEDVPAA-GILHAGDLITEIDGQSFKSSQEFIDYIHSKKVGDTVKIKYKHGNK 61 Query: 351 PLEVEVTLDTSTSS 364 E + L Sbjct: 62 NEEASIKLTAIDKK 75 >5MM8-A nrPDB Length = 204 Score = 57.4 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 40/167 (23%), Positives = 69/167 (41%), Gaps = 23/167 (13%) Query: 90 GLGSGVIINASKGYVLTNNHVINQ----AQKI---SIQLNDGREFDAK-LIGSDDQSDIA 141 G G+G I+ K ++TN HV+ A I + + N+G + K ++ Q DIA Sbjct: 24 GSGTGFIVG--KNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYSGQEDIA 81 Query: 142 LLQIQNPSKLTQIA--------IADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSG 193 +L +++ + + + + + + + VG P +G Sbjct: 82 ILHVEDKAVHPKNRNFKDYTGILKIASEAKENERISIVGYPEPYINKFQM-----YESTG 136 Query: 194 LNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSV 240 L N I TDA + GNSG A+ N E++G++ PG S Sbjct: 137 KVLSVKGNMIITDAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKST 183 >2W7U-A nrPDB Length = 200 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 37/165 (22%), Positives = 59/165 (35%), Gaps = 40/165 (24%) Query: 104 VLTNNHVINQAQKI---------SIQLNDGREFDAK-LIGSDDQSDIALLQIQNP----- 148 ++TN H I ++ I S + G +D K ++ + D+A++ + Sbjct: 34 IVTNKH-IAKSNDIFKNRVSAHHSSKGKGGGNYDVKDIVEYPGKEDLAIVHVHETSTEGL 92 Query: 149 ---SKLTQIAIADSDKLRVGDFAVAVGNPFG-------LGQTATSGIVSALGRSGLNLEG 198 ++ AD K++ D +G P G T T +S Sbjct: 93 NFNKNVSYTKFADGAKVK--DRISVIGYPKGAQTKYKMFESTGTINHISGT--------- 141 Query: 199 LENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIG 243 F++ DA GNSG +LN ELIGI A G Sbjct: 142 ---FMEFDAYAQPGNSGSPVLNSKHELIGILYAGSGKDESEKNFG 183 >3I18-A nrPDB Length = 100 Score = 55.5 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGK 350 G +V V +A + AGD+IT ++G S E I + + G VK+ K Sbjct: 8 GVYVMSVKDDVPAADV-LHAGDLITEIDGNAFKSSQEFIDYIHSKKVGDTVKINYKHGDK 66 Query: 351 PLEVEVTLDTSTSS 364 + ++ L Sbjct: 67 NEQADIKLTAIDKK 80 >5C2Z-A nrPDB Length = 255 Score = 55.1 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 49/226 (21%), Positives = 88/226 (38%), Gaps = 47/226 (20%) Query: 58 VEGTASQGQKIPEEFKKFFGDDLPDQP-----AQPFEGLGSGVI--------INASKGYV 104 +E T + QK + FK D P+ +G+ + I K V Sbjct: 8 IEYTDEEIQKKRDFFKTRPSDSELFSKIQDTTRSPYSSVGTVFVKGKTIATGILIGKNTV 67 Query: 105 LTNNHVI----NQAQKISIQLNDGREFDAKLIG---------------SDDQSDIALLQI 145 +TN H+ N K+ R+ + ++ +D++++++ Sbjct: 68 ITNKHIARLAENDPNKVIFTPGSTRDEGSLVVKKPFGEFIAEEINEAPYGGGTDLSIIKL 127 Query: 146 Q-------NPSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEG 198 + +T AI D+ ++ GD +G P+ T+T +L +S + + Sbjct: 128 KPNQYGKSAGDLVTPAAIPDNVDVQKGDKISLLGYPY---NTSTH----SLYKSQIEVFN 180 Query: 199 LENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGF 244 + F Q A GNSG + NL+GEL+GI++ G GI F Sbjct: 181 NQTF-QYFAYTEPGNSGSGIFNLHGELVGIHSGKGGQYGLPFGILF 225 >1DT2-A nrPDB Length = 245 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 43/221 (19%), Positives = 80/221 (36%), Gaps = 53/221 (23%) Query: 62 ASQGQKIPEEFKKFFGDDLPDQPAQPFEGLGSGVIINAS--------KGYVLTNNHVINQ 113 Q ++P K+ + + D P+ +G+ + ++ K ++TN HV + Sbjct: 10 LKQKFEVPPTDKELY-THITDNARSPYNSVGTVFVKGSTLATGVLIGKNTIVTNYHVARE 68 Query: 114 A----QKISIQLNDGR------------EFDAKLIG---SDDQSDIALLQIQNPSK---- 150 A I R +F+A+ I D+A+++++ K Sbjct: 69 AAKNPSNIIFTPAQNRDAEKNEFPTPYGKFEAEEIKESPYGQGLDLAIIKLKPNEKGESA 128 Query: 151 ---LTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 + I D ++ GD +G P+ S +L + + D+ Sbjct: 129 GDLIQPANIPDHIDIQKGDKYSLLGYPYNY--------------SAYSLYQSQIEMFNDS 174 Query: 208 SI----NRGNSGGALLNLNGELIGINTAILAPGGGSVGIGF 244 GNSG + NL GELIGI++ +G+ F Sbjct: 175 QYFGYTEVGNSGSGIFNLKGELIGIHSGKGGQHNLPIGVFF 215 >4JCN-A nrPDB Length = 216 Score = 54.0 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 38/157 (24%), Positives = 65/157 (41%), Gaps = 27/157 (17%) Query: 91 LGSGVIINASKGYVLTNNHVINQA----QKISIQLN--------DGREFDAKLIGSDDQS 138 GSGV++ ++ +LTN HV+N A + IS+ + +G+ ++I S Sbjct: 35 SGSGVVVGENE--ILTNKHVVNGAKGNPRNISVHPSAKNENDYPNGKFVGQEIIPYPGNS 92 Query: 139 DIALLQIQNPSKLTQI-------AIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR 191 D+A+L++ I I+ + R+ + G P G AT Sbjct: 93 DLAILRVSPNEHNQHIGQVVKPATISSNTDTRINENITVTGYP-GDKPLATM-----WES 146 Query: 192 SGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGI 228 G + ++ D S GNSG + N ++IGI Sbjct: 147 VGKVVYIGGEELRYDLSTVGGNSGSPVFNGKNQVIGI 183 >4QL6-A nrPDB Length = 634 Score = 53.2 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 51/140 (36%), Gaps = 15/140 (10%) Query: 226 IGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFN 285 IGIN F + + +++A L + M A + K Sbjct: 183 IGINDHGYRMSPEEEANSFHV--RIIKSIAHSL---DAHTAYFSQEEALSMRAQLEKGMC 237 Query: 286 ------LDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTE-- 336 + G V EVL G + K G ++ GDII +NGK + + + + Sbjct: 238 GIGVVLKEDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIEN-TPFPGVLDSLRGS 296 Query: 337 PGTKVKLGLLRNGKPLEVEV 356 PG+ V L + R +++ Sbjct: 297 PGSSVTLDIHRQNNDHVIQL 316 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 385 LKDGGKGIKIDEVVKGSPAAQAG-LQKDDVIIGVNRDRVNS 424 LK+ G+ + EV+ G PA + G L+ D+I VN + + Sbjct: 243 LKEDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIEN 283 >1P1D-A nrPDB Length = 196 Score = 52.1 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 69/159 (43%), Gaps = 10/159 (6%) Query: 293 FVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSF--AELRSRIATTEPGTKVKLGLLRNG 349 +S + S + + G ++ GD + ++NG P E + + +KV L + + Sbjct: 39 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSITSKVTLEIEFD- 97 Query: 350 KPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAG-L 408 E + +S + G T+S + G + I ++ KGS A + G L Sbjct: 98 ---VAESVIPSSGTFHVKLPKKHSVELGITISSPSSRKPGDPLVISDIKKGSVAHRTGTL 154 Query: 409 QKDDVIIGVNRDRVN--SIAEMRKVLAAKPAIIALQIVR 445 + D ++ ++ R++ S+ + ++L ++ L+I + Sbjct: 155 ELGDKLLAIDNIRLDSCSMEDAVQILQQCEDLVKLKIRK 193 >4K1S-A nrPDB Length = 206 Score = 50.9 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 34/188 (18%), Positives = 63/188 (33%), Gaps = 25/188 (13%) Query: 91 LGSGVIINASKGYVLTNNHVINQ---AQKISIQLNDGREFDA-----KLIGSDDQSDIAL 142 +G ++ K +LTN HV +I+ N + K+I + D+++ Sbjct: 25 SATGFVVG--KNTILTNKHVSKNYKVGDRITAHPNSDKGNGGIYSIKKIINYPGKEDVSV 82 Query: 143 LQIQN---PSKLTQIAIADSDKL-------RVGDFAVAVGNPFGLGQTATSGIVSALGRS 192 +Q++ D+ + G+ +G P + Sbjct: 83 IQVEERAIERGPKGFNFNDNVTPFKYAAGAKAGERIKVIGYPHPYKNKYVL-----YEST 137 Query: 193 GLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMAR 252 G + + I A GNSG +LN N EL+GI+ A + + + Sbjct: 138 GPVMSVEGSSIVYSAHTESGNSGSPVLNSNNELVGIHFASDVKNDDNRNAYGVYFTPEIK 197 Query: 253 TLAQQLID 260 + ID Sbjct: 198 KFIAENID 205 >2XKX-A nrPDB Length = 721 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 32/146 (21%), Positives = 60/146 (41%), Gaps = 8/146 (5%) Query: 292 AFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGK 350 F+++++PG +A+ G ++ D I +N + + A E G+ V+L ++R Sbjct: 91 IFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKP 150 Query: 351 PLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAG-LQ 409 P E + + I + Q G I + ++++G A + G LQ Sbjct: 151 PAEKVMEIKLIKGPKGLGFSIAGGV------GNQHIPGDNSIYVTKIIEGGAAHKDGRLQ 204 Query: 410 KDDVIIGVNRDRVNSIAEMRKVLAAK 435 D I+ VN + + V A K Sbjct: 205 IGDKILAVNSVGLEDVMHEDAVAALK 230 Score = 47.0 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 35/81 (43%), Gaps = 9/81 (11%) Query: 264 IKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPL 322 I RG G+ + G F+S +L G + +G ++ GD I S+NG L Sbjct: 313 IHRGSTGLGF--------NIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 364 Query: 323 NSFAELRSRIATTEPGTKVKL 343 + + ++ IA G V + Sbjct: 365 RNASHEQAAIALKNAGQTVTI 385 >4JJ3-A nrPDB Length = 243 Score = 50.1 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 63/150 (42%), Gaps = 10/150 (6%) Query: 215 GGALLNLNGELIGINTAILAPGGGSVGIGFAIP--SNMARTLAQQLIDFGEIKRGLLGIK 272 G ++ G+ +G+ A+ G +P S+ + F E G++ Sbjct: 19 GAPIVGGQGQAMGLPVAMQRRRGEQRA---PVPALSDANGGFVAPNVQFSEAH--WQGME 73 Query: 273 GTEMSADIAKAFNLD-VQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSR 331 +S ++ + L G + E +A +G+ AGD++ ++NG+ + + +++ Sbjct: 74 ALPLSIELKRKLKLPLDLEGLLIDETSLN--AAVSGLLAGDVLVAINGRKVKTLKKMQKE 131 Query: 332 IATTEPGTKVKLGLLRNGKPLEVEVTLDTS 361 + + L + R G+ L + ++ + + Sbjct: 132 TRRVQMDRRASLTVYRKGRLLTLTLSEEKN 161 Score = 33.2 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 27/51 (52%), Gaps = 2/51 (3%) Query: 380 LSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRK 430 +L +G+ IDE AA +GL DV++ +N +V ++ +M+K Sbjct: 82 KRKLKLPLDLEGLLIDETSLN--AAVSGLLAGDVLVAINGRKVKTLKKMQK 130 >1WCZ-A nrPDB Length = 268 Score = 49.4 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 32/157 (20%), Positives = 57/157 (36%), Gaps = 27/157 (17%) Query: 91 LGSGVIINASKGYVLTNNHVIN------QAQKISIQLNDGREFD------AKLIGSDDQS 138 + SGV++ +LTN HV++ A K + + ++ + Sbjct: 35 IASGVVVGKDT--LLTNKHVVDATHGDPHALKAFPSAINQDNYPNGGFTAEQITKYSGEG 92 Query: 139 DIALLQIQNPSKLTQI-------AIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR 191 D+A+++ + I ++++ + +V G P G AT Sbjct: 93 DLAIVKFSPNEQNKHIGEVVKPATMSNNAETQVNQNITVTGYP-GDKPVATM-----WES 146 Query: 192 SGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGI 228 G +Q D S GNSG + N E+IGI Sbjct: 147 KGKITYLKGEAMQYDLSTTGGNSGSPVFNEKNEVIGI 183 >5G1D-A nrPDB Length = 201 Score = 47.4 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 36/161 (22%), Positives = 63/161 (39%), Gaps = 26/161 (16%) Query: 288 VQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLN--SFAELRSRIATTEPGTKVKLGL 345 V G FV V S ++ G++ GD + +NG+ S + + G K+ + + Sbjct: 35 VDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAF-GEKITMTI 93 Query: 346 LRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQ 405 +P E VT+ +S K G KI +VK S AA+ Sbjct: 94 R--DRPFERTVTMHKDSSGHVG---------------FIFKSG----KITSIVKDSSAAR 132 Query: 406 AGLQKDDVIIGVNRDRVNSIAEMR--KVLAAKPAIIALQIV 444 GL D I +N V + + + +L+ ++ + I+ Sbjct: 133 NGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 173 Score = 31.3 bits (69), Expect = 0.82, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 19/35 (54%) Query: 384 QLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVN 418 +LK GI + V SPA+ GL+ D ++ +N Sbjct: 31 RLKSVDNGIFVQLVQANSPASLVGLRFGDQVLQIN 65 >5A2P-A nrPDB Length = 163 Score = 47.0 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 36/161 (22%), Positives = 63/161 (39%), Gaps = 26/161 (16%) Query: 288 VQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLN--SFAELRSRIATTEPGTKVKLGL 345 V G FV V S ++ G++ GD + +NG+ S + + G K+ + + Sbjct: 23 VDNGIFVQLVQANSPASLVGLRFGDQVLQINGENCAGWSSDKAHKVLKQAF-GEKITMTI 81 Query: 346 LRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQ 405 +P E VT+ +S K G KI +VK S AA+ Sbjct: 82 R--DRPFERTVTMHKDSSGHVG---------------FIFKSG----KITSIVKDSSAAR 120 Query: 406 AGLQKDDVIIGVNRDRVNSIAEMR--KVLAAKPAIIALQIV 444 GL D I +N V + + + +L+ ++ + I+ Sbjct: 121 NGLLTDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 161 Score = 31.3 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 19/35 (54%) Query: 384 QLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVN 418 +LK GI + V SPA+ GL+ D ++ +N Sbjct: 19 RLKSVDNGIFVQLVQANSPASLVGLRFGDQVLQIN 53 >4FGM-A nrPDB Length = 597 Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 34/85 (40%), Gaps = 1/85 (1%) Query: 290 RGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNG 349 +G V V + AG+ AGD I +++ + ++ + PG V + R Sbjct: 496 QGLDVLNVYHDESAYHAGLSAGDKIIAIDHLQATEQS-VKRILERYIPGDTVTIHAFRRD 554 Query: 350 KPLEVEVTLDTSTSSSASAEMITPA 374 + + +E+T SS + P Sbjct: 555 ELMTLELTWQEPAKSSYVLSVEQPD 579 >5E6P-B nrPDB Length = 88 Score = 45.9 bits (107), Expect = 3e-05, Method: Composition-based stats. Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 292 AFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLL 346 V V PG + KAGVK GD I +NG + + + L + + G V L LL Sbjct: 30 VLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHL-EVVKLIKSGAYVALTLL 83 Score = 32.8 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 23/45 (51%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKV 431 G + + + V G A +AG+++ D II VN V + + + V Sbjct: 25 SGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVV 69 >2L4S-A nrPDB Length = 124 Score = 45.5 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 43/116 (37%), Gaps = 6/116 (5%) Query: 246 IPSNMARTLAQ--QLIDFGEIKRGLLGI---KGTEMSADIAKAFNLDVQRGAFVSEVLPG 300 IP + Q ++ + + +LG G + +G +V+ V G Sbjct: 4 IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63 Query: 301 SGSAKAGVKAGDIITSLNGKPLNSFAELRSRIA-TTEPGTKVKLGLLRNGKPLEVE 355 + AG++ GD I +NG + ++R T V+L + R V+ Sbjct: 64 GPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQ 119 Score = 33.2 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 34/86 (39%), Gaps = 7/86 (8%) Query: 334 TTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDG-GKGI 392 + PG V + R VE+ + I ++ + +D KGI Sbjct: 2 SYIPGQPVTAVVQR------VEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGI 55 Query: 393 KIDEVVKGSPAAQAGLQKDDVIIGVN 418 + V +G PA AGLQ D I+ VN Sbjct: 56 YVTRVSEGGPAEIAGLQIGDKIMQVN 81 >2DLS-A nrPDB Length = 93 Score = 45.5 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 20/55 (36%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 292 AFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLL 346 V V PG + KAGVK GD I +NG + + + L + + G V L LL Sbjct: 31 VLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHL-EVVKLIKSGAYVALTLL 84 Score = 32.4 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 23/45 (51%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKV 431 G + + + V G A +AG+++ D II VN V + + + V Sbjct: 26 SGDRIVLVQSVRPGGAAMKAGVKEGDRIIKVNGTMVTNSSHLEVV 70 >2VZ5-A nrPDB Length = 139 Score = 44.3 bits (103), Expect = 9e-05, Method: Composition-based stats. Identities = 22/119 (18%), Positives = 40/119 (33%), Gaps = 3/119 (2%) Query: 238 GSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEV 297 G+ + F +L + G G + +G +V+ V Sbjct: 14 GTENLYFQSMVQRVE--IHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRV 71 Query: 298 LPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIA-TTEPGTKVKLGLLRNGKPLEVE 355 G + AG++ GD I +NG + ++R T V+L + R V+ Sbjct: 72 SEGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQ 130 Score = 33.6 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 25/118 (21%), Positives = 47/118 (39%), Gaps = 13/118 (11%) Query: 339 TKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVV 398 +V++ LR G+ L + ++ P E T KGI + V Sbjct: 25 QRVEIHKLRQGENLILGFSIGGGIDQD---PSQNPFSEDKT---------DKGIYVTRVS 72 Query: 399 KGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLA-AKPAIIALQIVRGNESIYLLMR 455 +G PA AGLQ D I+ VN + + + K + ++++ +S+ ++ Sbjct: 73 EGGPAEIAGLQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQSLQKAVQ 130 >2V90-A nrPDB Length = 96 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 20/77 (25%), Positives = 36/77 (46%) Query: 280 IAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGT 339 + + LD + G F+ EV PG + KAG++AGD + ++ G+ + + G+ Sbjct: 20 LREEKGLDGRPGQFLWEVDPGLPAKKAGMQAGDRLVAVAGESVEGLGHEETVSRIQGQGS 79 Query: 340 KVKLGLLRNGKPLEVEV 356 V L ++ E V Sbjct: 80 CVSLTVVDPEADRETSV 96 >2PKT-A nrPDB Length = 91 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 35/70 (50%) Query: 285 NLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLG 344 D ++ +S V PGS +A A + GD+IT+++G+ ++ L ++ + L Sbjct: 22 GKDFEQPLAISRVTPGSKAALANLCIGDVITAIDGENTSNMTHLEAQNRIKGCTDNLTLT 81 Query: 345 LLRNGKPLEV 354 + R+ ++ Sbjct: 82 VARSEHESDL 91 >2HLC-A nrPDB Length = 230 Score = 42.4 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 36/209 (17%), Positives = 80/209 (38%), Gaps = 38/209 (18%) Query: 70 EEFKKFFGDDLPDQPAQPFEGLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDA 129 F G D+ Q + GS +I+ ++LT H ++ A + + L +++ Sbjct: 10 GLFPYQAGLDITLQDQRRVWCGGS--LIDNK--WILTAAHCVHDAVSVVVYLGSAVQYEG 65 Query: 130 KLIG----------SDDQS---DIALLQIQNPS---KLTQIAIADSDKLRVG-DFAVAVG 172 + + + + D+AL++I + + I + ++L + A Sbjct: 66 EAVVNSERIISHSMFNPDTYLNDVALIKIPHVEYTDNIQPIRLPSGEELNNKFENIWATV 125 Query: 173 NPFGLGQTATSGIVSALGRSGLNLEGLENF---IQTDASI--------NR--GNSGGALL 219 + +G T T + N + + I +++I + G+SGG + Sbjct: 126 SGWGQSNTDTVILQYTYNLVIDNDRCAQEYPPGIIVESTICGDTSDGKSPCFGDSGGPFV 185 Query: 220 -NLNGELIGINTAILAPGGGSVG--IGFA 245 + LIG+ + ++ G G +GF+ Sbjct: 186 LSDKNLLIGV-VSFVSGAGCESGKPVGFS 213 >4C2G-A nrPDB Length = 446 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 18/82 (21%), Positives = 31/82 (37%), Gaps = 5/82 (6%) Query: 292 AFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTE--PGTKVKLGLLRNG 349 + S + KAG+K D I S+NG+ + +L + G+ V + + R G Sbjct: 83 IIIVSPFKKSPAEKAGLKPNDEIISINGESMA-GKDLNHAVLKIRGKKGSSVSMKIQRPG 141 Query: 350 --KPLEVEVTLDTSTSSSASAE 369 K L + + A Sbjct: 142 TKKQLSFRIKRAEIPLETVFAS 163 Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 46/101 (45%), Gaps = 11/101 (10%) Query: 349 GKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGL 408 P V + T+ S S + + GA + ++DG I I K SPA +AGL Sbjct: 46 NDPYSVYMDKQTAKQFSDSLDSSFEGI-GAEV---GMEDGK--IIIVSPFKKSPAEKAGL 99 Query: 409 QKDDVIIGVNRDRVNSIAEMRKVL----AAKPAIIALQIVR 445 + +D II +N + + ++ + K + ++++I R Sbjct: 100 KPNDEIISINGESMAG-KDLNHAVLKIRGKKGSSVSMKIQR 139 >3TSW-A nrPDB Length = 391 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 277 SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS--FAELRSRIAT 334 S + A DV G FV+ VL S +AK G++ GD I +N + E + Sbjct: 20 SVGLRLAGGNDV--GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLD 77 Query: 335 TEPGTKVKL 343 G +V + Sbjct: 78 LPKGEEVTI 86 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRG 446 GI + V++ SPAA+ GL++ D I+ VN + ++ + + L + +G Sbjct: 28 GNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNV------DFTNIIREEAVLFLLDLPKG 81 Query: 447 NESIYL 452 E L Sbjct: 82 EEVTIL 87 >3SHW-A nrPDB Length = 468 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 277 SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS--FAELRSRIAT 334 S + A DV G FV+ VL S +AK G++ GD I +N + E + Sbjct: 12 SVGLRLAGGNDV--GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLD 69 Query: 335 TEPGTKVKL 343 G +V + Sbjct: 70 LPKGEEVTI 78 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRG 446 GI + V++ SPAA+ GL++ D I+ VN + ++ + + L + +G Sbjct: 20 GNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNV------DFTNIIREEAVLFLLDLPKG 73 Query: 447 NESIYL 452 E L Sbjct: 74 EEVTIL 79 >5ZDS-A nrPDB Length = 96 Score = 42.0 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 291 GAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNG 349 G +V ++PG +AK G + GD + ++G L ++ PG +L L R G Sbjct: 37 GIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERRG 96 >4O06-A nrPDB Length = 106 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 38/72 (52%), Gaps = 2/72 (2%) Query: 292 AFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSR--IATTEPGTKVKLGLLRNG 349 AF+SEV+PGS S KA +K D + S+ + ++L++ + + + LLR G Sbjct: 21 AFISEVVPGSPSDKADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREG 80 Query: 350 KPLEVEVTLDTS 361 + L+ +T + Sbjct: 81 QILKTSLTPSRN 92 >4Q2Q-A nrPDB Length = 102 Score = 40.5 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 277 SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS--FAELRSRIAT 334 S + A DV G FV+ VL S +AK G++ GD I +N + E + Sbjct: 18 SVGLRLAGGNDV--GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLD 75 Query: 335 TEPGTKVKL 343 G +V + Sbjct: 76 LPKGEEVTI 84 Score = 38.2 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRG 446 GI + V++ SPAA+ GL++ D I+ VN + ++ + + L + +G Sbjct: 26 GNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNV------DFTNIIREEAVLFLLDLPKG 79 Query: 447 NESIYL 452 E L Sbjct: 80 EEVTIL 85 >3TSV-A nrPDB Length = 124 Score = 40.5 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 277 SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS--FAELRSRIAT 334 S + A DV G FV+ VL S +AK G++ GD I +N + E + Sbjct: 40 SVGLRLAGGNDV--GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLD 97 Query: 335 TEPGTKVKL 343 G +V + Sbjct: 98 LPKGEEVTI 106 Score = 38.2 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRG 446 GI + V++ SPAA+ GL++ D I+ VN + ++ + + L + +G Sbjct: 48 GNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNV------DFTNIIREEAVLFLLDLPKG 101 Query: 447 NESIYL 452 E L Sbjct: 102 EEVTIL 107 >1UF1-A nrPDB Length = 128 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 1/78 (1%) Query: 285 NLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLG 344 + G +++ V PGS + +G+K GD I +NG+ + + + + L Sbjct: 41 GAEYGLGIYITGVDPGSEAEGSGLKVGDQILEVNGRSFLNILH-DEAVRLLKSSRHLILT 99 Query: 345 LLRNGKPLEVEVTLDTST 362 + G+ T+D + Sbjct: 100 VKDVGRLPHARTTVDETK 117 >3K50-A nrPDB Length = 403 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 40/95 (42%), Gaps = 5/95 (5%) Query: 280 IAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAE---LRSRIATTE 336 + K + D A +S V+PGS + +AG++ G I +NG + E L+ + Sbjct: 80 LYKVLDNDTAYNALISYVVPGSPAEEAGLQRGHWIMMMNGDYITKKVESELLQGSTRQLQ 139 Query: 337 PGTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMI 371 G V ++ + V T+ AS ++ Sbjct: 140 IG--VYKEVVGEDGEVTGGVVPIGETTMPASRSLV 172 Score = 32.0 bits (71), Expect = 0.61, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 28/59 (47%), Gaps = 1/59 (1%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVR 445 D I VV GSPA +AGLQ+ I+ +N D + E ++L + + + + Sbjct: 87 DTAYNALISYVVPGSPAEEAGLQRGHWIMMMNGDYITKKVE-SELLQGSTRQLQIGVYK 144 >3QDO-A nrPDB Length = 109 Score = 39.3 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 45/112 (40%), Gaps = 11/112 (9%) Query: 248 SNMARTLAQQLIDFGEIKRGLL--GIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAK 305 S + + +G RG + G + ++ ++ VS VLPG + + Sbjct: 6 SPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQ-------HVSAVLPGGAADR 58 Query: 306 AGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTK-VKLGLLRNGKPLEVEV 356 AGV+ GD I +NG + + + G K + L +L G E +V Sbjct: 59 AGVRKGDRILEVNGVNVEGATH-KQVVDLIRAGEKELILTVLSVGGESESKV 109 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 26/53 (49%), Gaps = 2/53 (3%) Query: 394 IDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSI--AEMRKVLAAKPAIIALQIV 444 + V+ G A +AG++K D I+ VN V ++ ++ A + L ++ Sbjct: 47 VSAVLPGGAADRAGVRKGDRILEVNGVNVEGATHKQVVDLIRAGEKELILTVL 99 >2QBW-A nrPDB Length = 195 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 4/74 (5%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR--- 347 G FV+ V P ++K ++ GD I NG + ++ V+L ++R Sbjct: 25 GIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVG 83 Query: 348 NGKPLEVEVTLDTS 361 NG E+ V ++ Sbjct: 84 NGAKQEIRVRVEKD 97 >1FC9-A nrPDB Length = 388 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 35/197 (17%), Positives = 69/197 (35%), Gaps = 40/197 (20%) Query: 292 AFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAEL-RSRIATTEPGTKVKLGLLRNGK 350 V PG + KAG +AGD+I +++G + + S + E ++V++ L G Sbjct: 101 VVVLTPAPGGPAEKAGARAGDVIVTVDGTAVKGLSLYDVSDLLQGEADSQVEVVLHAPGA 160 Query: 351 P---LEVE-----VTLDTSTSSS-----------------------ASAEMITPALEGAT 379 P ++ VT++ T ++ A+ T A Sbjct: 161 PSNTRTLQLTRQKVTINPVTFTTCSNVAAAALPPGAAKQQLGYVRLATFNSNTTAAAQQA 220 Query: 380 LSDGQLKDGGKGIKIDEVVKGSPAAQAGLQ-------KDDVIIGVNRDRVNSIAEMRKVL 432 ++ K G G+ +D G AG+ + D+++ + + I Sbjct: 221 FTELS-KQGVAGLVLDIRNNGGGLFPAGVNVARMLVDRGDLVLIADSQGIRDIYSADGNS 279 Query: 433 AAKPAIIALQIVRGNES 449 + + + RG S Sbjct: 280 IDSATPLVVLVNRGTAS 296 Score = 31.3 bits (69), Expect = 0.96, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 23/52 (44%) Query: 375 LEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIA 426 + G L GK + + G PA +AG + DVI+ V+ V ++ Sbjct: 84 VTGVGLEITYDGGSGKDVVVLTPAPGGPAEKAGARAGDVIVTVDGTAVKGLS 135 >3SHU-A nrPDB Length = 95 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 4/69 (5%) Query: 277 SADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNS--FAELRSRIAT 334 S + A DV G FV+ VL S +AK G++ GD I +N + E + Sbjct: 15 SVGLRLAGGNDV--GIFVAGVLEDSPAAKEGLEEGDQILRVNNVDFTNIIREEAVLFLLD 72 Query: 335 TEPGTKVKL 343 G +V + Sbjct: 73 LPKGEEVTI 81 Score = 37.0 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 6/66 (9%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRG 446 GI + V++ SPAA+ GL++ D I+ VN + ++ + + L + +G Sbjct: 23 GNDVGIFVAGVLEDSPAAKEGLEEGDQILRVNNV------DFTNIIREEAVLFLLDLPKG 76 Query: 447 NESIYL 452 E L Sbjct: 77 EEVTIL 82 >3CH8-A nrPDB Length = 195 Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 32/74 (43%), Gaps = 4/74 (5%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR--- 347 G FV+ V P ++K ++ GD I NG + ++ V+L ++R Sbjct: 26 GIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVREVG 84 Query: 348 NGKPLEVEVTLDTS 361 NG E+ V ++ Sbjct: 85 NGAKQEIRVRVEKD 98 >1UEZ-A nrPDB Length = 101 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 29/66 (43%), Gaps = 1/66 (1%) Query: 285 NLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLG 344 + G +VS V PGS + K G++ GD I +N K L + + K+ L Sbjct: 30 GSEHGVGIYVSLVEPGSLAEKEGLRVGDQILRVNDKSLARVTH-AEAVKALKGSKKLVLS 88 Query: 345 LLRNGK 350 + G+ Sbjct: 89 VYSAGR 94 >2KBS-A nrPDB Length = 92 Score = 37.8 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 283 AFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVK 342 + + G F+S V PGS SA+ G++ GD I +NG ++ + + + + Sbjct: 20 SSGPIQKPGIFISHVKPGSLSAEVGLEIGDQIVEVNGVDFSNLDH-KEAVNVLKSSRSLT 78 Query: 343 LGLL 346 + ++ Sbjct: 79 ISIV 82 >1M5Z-A nrPDB Length = 91 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 14/60 (23%), Positives = 23/60 (38%) Query: 289 QRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRN 348 ++G +V + P G+K D + +N F E G K+ L + RN Sbjct: 31 EKGVYVKNIRPAGPGDLGGLKPYDRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISRN 90 >5N7D-A nrPDB Length = 427 Score = 37.8 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 19/105 (18%), Positives = 39/105 (37%), Gaps = 15/105 (14%) Query: 247 PSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKA 306 PS + ++++ G T + D F + ++ +A Sbjct: 12 PSELKGKFIHT-----KLRKSSRGFGFTVVGGDEPDEF-------LQIKSLVLDGPAALD 59 Query: 307 G-VKAGDIITSLNGKPL--NSFAELRSRIATTEPGTKVKLGLLRN 348 G ++ GD+I S+N + ++ A++ + G V L L R Sbjct: 60 GKMETGDVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRG 104 >3K1R-A nrPDB Length = 192 Score = 37.4 bits (85), Expect = 0.012, Method: Composition-based stats. Identities = 19/104 (18%), Positives = 42/104 (40%), Gaps = 8/104 (7%) Query: 247 PSNMARTLAQQLIDFGEIKRGLLGIKGTEMSAD---IAKAFNLDVQRGAFVSEVLPGSGS 303 P + + R L ++ + + ++ L+ G F+S ++ G + Sbjct: 64 PLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQA 123 Query: 304 AKAGVKAGDIITSLNGKPLNSF--AELRSRIATTEPGTKVKLGL 345 G++ GD I +NG ++S E+ + I T + V + + Sbjct: 124 DSVGLQVGDEIVRINGYSISSCTHEEVINLIRTEK---TVSIKV 164 >1X5N-A nrPDB Length = 114 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 31/64 (48%), Gaps = 1/64 (1%) Query: 283 AFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVK 342 + + G F+S V PGS SA+ G++ GD I +NG ++ + + + + Sbjct: 34 SSGPIQKPGIFISHVKPGSLSAEVGLEIGDQIVEVNGVDFSNLDH-KEAVNVLKSSRSLT 92 Query: 343 LGLL 346 + ++ Sbjct: 93 ISIV 96 >2LOB-A nrPDB Length = 112 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 31/79 (39%), Gaps = 9/79 (11%) Query: 267 GLLGIKGTEMSADIAKAFNLDVQRG------AFVSEVLPGSGSAK-AGVKAGDIITSLNG 319 GI+ + + + + + G +SE+ PG + + G+ GD I ++NG Sbjct: 24 YFQGIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNG 83 Query: 320 KPLNSF--AELRSRIATTE 336 L E + ++ Sbjct: 84 VNLRDTKHKEAVTILSQQR 102 >2R4H-A nrPDB Length = 112 Score = 37.0 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 285 NLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKL 343 + +V + + ++G ++ GD I +NG+ + R+ G +V+L Sbjct: 44 GREYNMDLYVLRLAEDGPAERSGKMRIGDEILEINGETTKNMKHSRAIELIKNGGRRVRL 103 Query: 344 GLLRN 348 L R Sbjct: 104 FLKRG 108 >1MFG-A nrPDB Length = 95 Score = 36.6 bits (83), Expect = 0.019, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 25/58 (43%), Gaps = 1/58 (1%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRN 348 G FV+ V P ++K ++ GD I NG + ++ V+L ++R Sbjct: 36 GIFVTRVQPEGPASKL-LQPGDKIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVRE 92 >1AZZ-A nrPDB Length = 226 Score = 36.6 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 39/169 (23%), Positives = 64/169 (37%), Gaps = 39/169 (23%) Query: 94 GVIINASKGYVLTNNHVINQAQKISIQLN--DGREFDAKLIGSDD--------------Q 137 G +I+ ++LT H ++ A + + L + RE +A + Sbjct: 28 GSLISPE--WILTAAHCMDGAGFVDVVLGAHNIREDEATQVTIQSTDFTVHENYNSFVIS 85 Query: 138 SDIALLQIQNPSKLTQIAIAD---SDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGL 194 +DIA++++ P LT S + VG G +GL + GI L + + Sbjct: 86 NDIAVIRLPVPVTLTAAIATVGLPSTDVGVGTVVTPTG--WGLPSDSALGISDVLRQVDV 143 Query: 195 NLEGLEN-----FIQTDASI----------NRGNSGGALLNLNGELIGI 228 + + I TD +I G+SGG L N NG GI Sbjct: 144 PIMSNADCDAVYGIVTDGNICIDSTGGKGTCNGDSGGPL-NYNGLTYGI 191 >4XZY-A nrPDB Length = 720 Score = 36.3 bits (82), Expect = 0.025, Method: Composition-based stats. Identities = 12/19 (63%), Positives = 15/19 (78%) Query: 212 GNSGGALLNLNGELIGINT 230 GNSG ++N NGELIG+N Sbjct: 653 GNSGSPVMNANGELIGLNF 671 >1WFV-A nrPDB Length = 103 Score = 36.3 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 24/65 (36%), Gaps = 1/65 (1%) Query: 285 NLDVQRGAFVSEVLPGSGS-AKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKL 343 + + +V + + ++ GD I +NG+ R+ G +V+L Sbjct: 31 GREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHARAIELIKSGGRRVRL 90 Query: 344 GLLRN 348 L R Sbjct: 91 LLKRG 95 >5HJ1-A nrPDB Length = 103 Score = 36.3 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 32/68 (47%), Gaps = 3/68 (4%) Query: 296 EVLPGSGSA---KAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPL 352 + PG ++ ++G++A D+ +LNG L + + + T++ L + R G+ Sbjct: 35 RLNPGKDASLFRQSGLQANDLAIALNGIDLRDQEQAQQALQNLADMTEITLTVEREGQRH 94 Query: 353 EVEVTLDT 360 ++ L Sbjct: 95 DIAFALGD 102 >3CYY-A nrPDB Length = 92 Score = 36.3 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 36/76 (47%), Gaps = 1/76 (1%) Query: 282 KAFNLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTK 340 + + L + FV E+ S +A+ G ++ GD++ +NG + + ++ K Sbjct: 15 EEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGK 74 Query: 341 VKLGLLRNGKPLEVEV 356 +K+ + R+ + + V Sbjct: 75 LKMVVQRDERATLLNV 90 >1UEQ-A nrPDB Length = 123 Score = 35.9 bits (81), Expect = 0.034, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 29/67 (43%), Gaps = 3/67 (4%) Query: 285 NLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPL--NSFAELRSRIATTEPGTKV 341 + V V+P +A+ G ++ GD+I +N + ++ A++ + G V Sbjct: 39 GDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSV 98 Query: 342 KLGLLRN 348 L L R Sbjct: 99 NLVLCRG 105 >2JIL-A nrPDB Length = 97 Score = 35.9 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 287 DVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGL 345 + R ++ V PG + + G +K GD + S++G L + + G + L + Sbjct: 29 NKSRPVVITSVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEAALLI 88 Query: 346 LRN 348 + Sbjct: 89 EYD 91 >3G8Q-A nrPDB Length = 278 Score = 35.5 bits (80), Expect = 0.045, Method: Composition-based stats. Identities = 27/155 (17%), Positives = 52/155 (33%), Gaps = 23/155 (14%) Query: 289 QRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGT--------- 339 + G V EV P V D++ + G P + ++ +R+ G Sbjct: 98 RSGVEVVEVHPDEPLGYDPVDRLDVLLTFGGNPYLTEEDVAARVYCLLTGRGFDADIAPA 157 Query: 340 ------KVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIK 393 +V++ + R VE+ + +I+ + L + L+D I Sbjct: 158 PENLSGRVEIMVTRGDPDEAVELLKEELPVFRIRRFLISGEFDRDELRERILEDIEPRIL 217 Query: 394 --------IDEVVKGSPAAQAGLQKDDVIIGVNRD 420 I S + +A + DV+ V R+ Sbjct: 218 DPFAVRARIARAGAFSSSREAEVFIGDVLTSVGRE 252 >5JWG-A nrPDB Length = 703 Score = 35.5 bits (80), Expect = 0.052, Method: Composition-based stats. Identities = 10/19 (52%), Positives = 14/19 (73%) Query: 212 GNSGGALLNLNGELIGINT 230 GN+G ++N GELIG+N Sbjct: 630 GNAGSPVMNARGELIGLNF 648 >5JXF-A nrPDB Length = 731 Score = 35.5 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 9/19 (47%), Positives = 12/19 (63%) Query: 212 GNSGGALLNLNGELIGINT 230 GNSG ++ G LIG+N Sbjct: 660 GNSGSPAVDAQGNLIGLNF 678 >2RCZ-A nrPDB Length = 81 Score = 35.5 bits (80), Expect = 0.053, Method: Composition-based stats. Identities = 17/80 (21%), Positives = 38/80 (47%), Gaps = 1/80 (1%) Query: 270 GIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAEL 328 G K T + + + + L + FV E+ S +A+ G ++ GD++ +NG + + Sbjct: 1 GSKVTLVKSRKNEEYGLRLASHIFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLT 60 Query: 329 RSRIATTEPGTKVKLGLLRN 348 ++ K+K+ + R+ Sbjct: 61 DAKTLIERSKGKLKMVVQRD 80 >4JOF-A nrPDB Length = 87 Score = 35.1 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 3/76 (3%) Query: 264 IKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAK-AGVKAGDIITSLNGKPL 322 R +L +K I+ + +SE+ PG + + G+ GD I ++NG L Sbjct: 2 PIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 61 Query: 323 NSF--AELRSRIATTE 336 E + ++ Sbjct: 62 RDTKHKEAVTILSQQR 77 >3WOM-A nrPDB Length = 698 Score = 35.1 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 17/26 (65%) Query: 205 TDASINRGNSGGALLNLNGELIGINT 230 +D I GNSG +L+ +G+L+G+ Sbjct: 624 SDLDITGGNSGSPVLDAHGKLVGLAF 649 >2DC2-A nrPDB Length = 103 Score = 35.1 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 3/76 (3%) Query: 264 IKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAK-AGVKAGDIITSLNGKPL 322 R +L +K I+ + +SE+ PG + + G+ GD I ++NG L Sbjct: 9 PIRKVLLLKEDHEGLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 68 Query: 323 NSF--AELRSRIATTE 336 E + ++ Sbjct: 69 RDTKHKEAVTILSQQR 84 >4NXP-A nrPDB Length = 94 Score = 35.1 bits (79), Expect = 0.072, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 39/87 (44%), Gaps = 7/87 (8%) Query: 262 GEIKRGLLGIKGTEMSADI----AKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSL 317 G++ + I+ ++ +AD + D R +V+ V ++K G+KAGD I + Sbjct: 4 GKVTHS-IHIEKSDTAADTYGFSLSSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEI 62 Query: 318 NGKPLN--SFAELRSRIATTEPGTKVK 342 N + + + + + + G V+ Sbjct: 63 NNRAADALNSSMMEDFFSQPSVGLLVR 89 >2D8I-A nrPDB Length = 114 Score = 34.7 bits (78), Expect = 0.078, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 30/63 (47%), Gaps = 2/63 (3%) Query: 282 KAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLN--SFAELRSRIATTEPGT 339 + D R +V+ V ++K G+KAGD I +N + + + + L+ ++ G Sbjct: 36 SSVEEDGIRRLYVNSVKETGLASKKGLKAGDEILEINNRAADALNSSMLKDFLSQPSLGL 95 Query: 340 KVK 342 V+ Sbjct: 96 LVR 98 >1X5R-A nrPDB Length = 112 Score = 34.7 bits (78), Expect = 0.079, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 33/89 (37%), Gaps = 13/89 (14%) Query: 276 MSADIAKAFNLDVQRGAFVSE----------VLPGSGSAKAG-VKAGDIITSLNGKPLNS 324 + D F L +Q G F +E + P S + + G ++ GD + S+NG Sbjct: 21 LCGDPLSGFGLQLQGGIFATETLSSPPLVCFIEPDSPAERCGLLQVGDRVLSINGIATED 80 Query: 325 F--AELRSRIATTEPGTKVKLGLLRNGKP 351 E + KV L + + P Sbjct: 81 GTMEEANQLLRDAALAHKVVLEVEFDSGP 109 >2QT5-A nrPDB Length = 200 Score = 34.7 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 27/63 (42%), Gaps = 1/63 (1%) Query: 287 DVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGL 345 + R ++ V PG + + G +K GD + S++G L + + G + L + Sbjct: 132 NKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLI 191 Query: 346 LRN 348 + Sbjct: 192 EYD 194 Score = 34.3 bits (77), Expect = 0.100, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 54/143 (37%), Gaps = 5/143 (3%) Query: 280 IAKAFNLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPG 338 + + +D VS + G +A++ + GD I ++NG L F G Sbjct: 23 LTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEIISLLKNVG 82 Query: 339 TKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKG--IKIDE 396 +V L + P+ ++ + + + G + G D K + I Sbjct: 83 ERVVLEVEYELPPVSIQGSSVMFRTVEVTLHKEGNT-FGFVIRGGAHDDRNKSRPVVITC 141 Query: 397 VVKGSPAAQAG-LQKDDVIIGVN 418 V G PA + G ++ D ++ V+ Sbjct: 142 VRPGGPADREGTIKPGDRLLSVD 164 >1YJS-A nrPDB Length = 419 Score = 34.7 bits (78), Expect = 0.080, Method: Composition-based stats. Identities = 42/217 (19%), Positives = 73/217 (33%), Gaps = 24/217 (11%) Query: 173 NPFGLGQTATSGIVSALG--RSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINT 230 NP T+ L R G+ L + Q D +I G GG L+ +I Sbjct: 212 NPVPYAHFVTTTTHQTLRGPRGGMILCQEQFAKQIDKAIFPGIQGGPLM----HVIAAKA 267 Query: 231 AILAPGGGSVGIGFAIP-SNMARTLAQQLIDFG--------EIKRGLLGIKGTEMSADIA 281 +A + A+ LA L + G + L+ ++ +++ A Sbjct: 268 VAFGEALQDDFKAYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTA 327 Query: 282 KAFNLDVQRGAFVSE----VLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEP 337 + +V G V++ P S +G++ G + G L E+ + I Sbjct: 328 EKVLDEV--GITVNKNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIAAIIGLVLK 385 Query: 338 GTKVKLGLLRNGKPLEVEVTLDTSTSSSASAEMITPA 374 + L + + L TS SA+ M A Sbjct: 386 NVGSEQALEEARQRVAA---LTDPTSRSAAGTMEFEA 419 >1P3E-A nrPDB Length = 215 Score = 34.7 bits (78), Expect = 0.081, Method: Composition-based stats. Identities = 31/174 (17%), Positives = 53/174 (30%), Gaps = 27/174 (15%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAK------------------- 130 +G +I +K +LTN H + G + Sbjct: 30 SSCTGTLIAPNK--ILTNGHCVYNTAS-RSYSAKGSVYPGMNDSTAVNGSANMTEFYVPS 86 Query: 131 --LIGSDDQSDIALLQIQNP-SKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVS 187 + Q D A+++ G G P + ++G VS Sbjct: 87 GYINTGASQYDFAVIKTDTNIGNTVGYRSIRQVTNLTGTTIKISGYP--GDKMRSTGKVS 144 Query: 188 ALGRSGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGSVG 241 SG N GNSG A+L+ N +++G++ A + G + G Sbjct: 145 QWEMSGSVTREDTNLAYYTIDTFSGNSGSAMLDQNQQIVGVHNAGYSNGTINGG 198 >1PQ7-A nrPDB Length = 224 Score = 34.7 bits (78), Expect = 0.082, Method: Composition-based stats. Identities = 33/159 (20%), Positives = 57/159 (35%), Gaps = 36/159 (22%) Query: 104 VLTNNHVINQAQKISIQLNDGR--EFDAKLIGS-----------DDQSDIALLQ----IQ 146 VLT H ++ + Q+ G + S + +D+A+L+ I Sbjct: 36 VLTAAHCVSGYAQSGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLSTSIP 95 Query: 147 NPSKLTQIAIADS-DKLRVGDFAVAVG---NPFGLGQT------ATSGIVS-ALGRSGLN 195 + + +A S G A G G T T IVS A R+ Sbjct: 96 SGGNIGYARLAASGSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYG 155 Query: 196 LEGLENFIQTDASIN-------RGNSGGALLNLNGELIG 227 + N + A ++ +G+SGG +++ + LIG Sbjct: 156 TSAITNQMFC-AGVSSGGKDSCQGDSGGPIVDSSNTLIG 193 >4WSI-A nrPDB Length = 394 Score = 34.7 bits (78), Expect = 0.086, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 41/124 (33%), Gaps = 7/124 (5%) Query: 292 AFVSEVLPGSGSAKAGV-KAGDIITSLNGKPL--NSFAELRSRIATTEPGTKVKLGLLRN 348 +S ++ G + K+G+ GD + +NG + E+ ++ L + Sbjct: 47 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQ 106 Query: 349 GKPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGL 408 KP + T+ + P + L KG + + + P Sbjct: 107 IKPPPAKETVIHVKAHFDYDPSDDPYVPCRELG----LSFQKGDILHVISQEDPNWWQAY 162 Query: 409 QKDD 412 ++ D Sbjct: 163 REGD 166 >1FUJ-A nrPDB Length = 221 Score = 34.3 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 31/158 (19%), Positives = 64/158 (40%), Gaps = 28/158 (17%) Query: 103 YVLTNNH-----------VINQAQKISIQLNDGREFD-AKLI-----GSDDQSDIALLQI 145 +VLT H V+ A + Q + F A++ + +DI L+Q+ Sbjct: 38 FVLTAAHCLRDIPQRLVNVVLGAHNVRTQEPTQQHFSVAQVFLNNYDAENKLNDILLIQL 97 Query: 146 QNPSKLT----QIAIADSDKLRV-GDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLE 200 +P+ L+ + + D+ G +A+G + ++ L + + Sbjct: 98 SSPANLSASVATVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRP 157 Query: 201 NFI-----QTDASINRGNSGGALLNLNGELIGINTAIL 233 + I + A I G+SGG L+ +G + GI++ ++ Sbjct: 158 HNICTFVPRRKAGICFGDSGGPLI-CDGIIQGIDSFVI 194 >2SFA-A nrPDB Length = 191 Score = 33.9 bits (76), Expect = 0.13, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 26/56 (46%), Gaps = 2/56 (3%) Query: 164 VGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGALL 219 VG G+ GL +G+ + + G ++ + IQT+ G+SGGAL Sbjct: 99 VGQTVQRSGSTTGLHSGRVTGLNATVNYGGGDI--VSGLIQTNVCAEPGDSGGALF 152 >3BPU-A nrPDB Length = 88 Score = 33.6 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 14/62 (22%), Positives = 32/62 (51%), Gaps = 4/62 (6%) Query: 291 GAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLN--SFAELRSRIATTEPGTKVKLGLLRN 348 G V +++ S ++ G+K GD+I +N K + + ++ + + G++V L + R Sbjct: 28 GQRVKQIV-DSPRSR-GLKEGDLIVEVNKKNVQALTHNQVVDMLVESPKGSEVTLLVQRQ 85 Query: 349 GK 350 + Sbjct: 86 TR 87 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 36/69 (52%), Gaps = 8/69 (11%) Query: 387 DGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKVLAAKPAIIALQIVRG 446 G G + + + SP ++ GL++ D+I+ VN+ V + + + + ++ +G Sbjct: 23 SPGGGGQRVKQIVDSPRSR-GLKEGDLIVEVNKKNV------QALTHNQVVDMLVESPKG 75 Query: 447 NESIYLLMR 455 +E + LL++ Sbjct: 76 SE-VTLLVQ 83 >2I6V-A nrPDB Length = 87 Score = 33.2 bits (74), Expect = 0.24, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 296 EVLPGSGS---AKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPL 352 V PG G++ GD+ +LNG L + + + T++ L + R+G+ Sbjct: 22 RVSPGKDPVLFESIGLQDGDMAVALNGLDLTDPNVMNTLFQSMNEMTEMSLTVERDGQQH 81 Query: 353 EVEV 356 +V + Sbjct: 82 DVYI 85 >2WV5-A nrPDB Length = 214 Score = 33.2 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 31/125 (24%), Positives = 54/125 (43%), Gaps = 11/125 (8%) Query: 126 EFDAKLIGSDDQSDIALLQIQNPSKLTQIA--IADSDKLRVGDFAVAVGNPFGLGQTATS 183 EF+ K+ G D SD AL+ + +K+ I D+ +++ G V V N +G+ S Sbjct: 72 EFEIKVKGQDMLSDAALMVLHRGNKVRDITKHFRDTARMKKGTPVVGVVNNADVGRLIFS 131 Query: 184 GIVSALGRSGL----NLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGGS 239 G AL + + + + A+ G +GGA+L +G + G Sbjct: 132 G--EALTYKDIVVLMDGDTMPGLFAYKAATRAGYAGGAVLAKDG---ADTFIVGTHSAGG 186 Query: 240 VGIGF 244 G+G+ Sbjct: 187 NGVGY 191 >3PVL-A nrPDB Length = 655 Score = 32.8 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 33/120 (27%), Gaps = 19/120 (15%) Query: 308 VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPLEVEVTLDTSTSSSAS 367 + D+I ++N + E + + + R K + TL T + Sbjct: 490 LPKSDVIVAVNWTGVYFVDEQEQVLLELSFPEIMAVSSSRGTKMMAPSFTLATIKGDEYT 549 Query: 368 AEMIT---------PALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAG---LQKDDVII 415 LEG K + + ++G K D+II Sbjct: 550 FTSSNAEDIRDLVVTFLEGLRKRS-------KYVVALQDNPNPAGEESGFLSFAKGDLII 602 >3SOE-A nrPDB Length = 113 Score = 32.8 bits (73), Expect = 0.31, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 22/47 (46%), Gaps = 2/47 (4%) Query: 307 GVKAGDIITSLNGKPLNSFA--ELRSRIATTEPGTKVKLGLLRNGKP 351 G++ GDII + + + + ++ + G V L +LR G P Sbjct: 49 GLQKGDIIKEIYHQNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPP 95 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 33/79 (41%), Gaps = 6/79 (7%) Query: 372 TPALEGATLSDGQLKDGGKGIKIDEVVKGSPAAQAGLQKDDVIIGVNRDRVNSIAEMRKV 431 P ++G + D G K+ ++ GLQK D+I + V ++ ++ V Sbjct: 16 IPLIKGPKGFGFAIADSPTGQKVKMILDSQ--WCQGLQKGDIIKEIYHQNVQNLTHLQVV 73 Query: 432 LAAK----PAIIALQIVRG 446 K A + L I+RG Sbjct: 74 EVLKQFPVGADVPLLILRG 92 >2I4S-A nrPDB Length = 105 Score = 32.8 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 29/64 (45%), Gaps = 3/64 (4%) Query: 296 EVLPGSGS---AKAGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNGKPL 352 V PG G++ GD+ +LNG L + + + T++ L + R+G+ Sbjct: 40 RVSPGKDPVLFESIGLQDGDMAVALNGLDLTDPNVMNTLFQSMNEMTEMSLTVERDGQQH 99 Query: 353 EVEV 356 +V + Sbjct: 100 DVYI 103 >1CT4-E nrPDB Length = 185 Score = 32.8 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 44/131 (33%), Gaps = 8/131 (6%) Query: 94 GV-IINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQ-----IQN 147 G + + S Y LT H + A S +D +++ I Sbjct: 17 GFNVRSGSTYYFLTAGHCTDGATTWWANSARTTVLGTTSGSSFPNNDYGIVRYTNTTIPK 76 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDA 207 + I + VG G+ G + + + + + G ++ + I+T+ Sbjct: 77 DGTVGGQDITSAANATVGMAVTRRGSTTGTHSGSVTALNATVNYGGGDV--VYGMIRTNV 134 Query: 208 SINRGNSGGAL 218 G+SGG L Sbjct: 135 CAEPGDSGGPL 145 >6FAH-A nrPDB Length = 396 Score = 32.4 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 75/206 (36%), Gaps = 20/206 (9%) Query: 127 FDAKLIGSDDQSDIALLQIQNPSKLTQIAIA-DSDKLRVGDFAVAVGNPF-------GLG 178 + A IG D +A+ ++ + D D ++ A G G Sbjct: 162 YGATHIGRDLAPCLAV-KVNTGLTADCTKLEIDPDDKKIRQTRPAFGGNLMATIVCPGSR 220 Query: 179 Q---TATSGIVSALGRSGLNLEGLENFIQTDASINRGNSGGA---LLNLNGELIGINTAI 232 T G+ + ++ + I+ DA+ N G+ ++ + I I+ A Sbjct: 221 PQMSTVRPGV---MDKAAYDPSQKGEVIKLDATFNEGDIRTKVLEIVKTTTDNISISDAD 277 Query: 233 LAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGA 292 GG +G+G + + LA +L R + + + + + V+ Sbjct: 278 FIVSGG-MGLGKPEGFELLKQLADKLGGTVATSRACVDAGWADHAQQVGQT-GTTVKPQI 335 Query: 293 FVSEVLPGSGSAKAGVKAGDIITSLN 318 + + + G+ AG++ DII ++N Sbjct: 336 YFACGISGAIQHIAGMQDSDIIIAIN 361 >1UJD-A nrPDB Length = 117 Score = 32.0 bits (71), Expect = 0.52, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 31/58 (53%), Gaps = 3/58 (5%) Query: 291 GAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSF--AELRSRIATTEPGTKVKLGL 345 GA+++++LPG + + G + G + NG PL S E++S I+ ++ + L Sbjct: 50 GAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTYEEVQSIISQQSGEAEICVRL 107 >2YO3-A nrPDB Length = 268 Score = 31.6 bits (70), Expect = 0.67, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 47/125 (37%), Gaps = 6/125 (4%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPS 149 +GSG I A L N V ++A +S+ + + + + +D + S Sbjct: 94 AIGSGSIAAAENSVALGTNSVADEANTVSVGSSTQQRRITNVAAGVNNTDAVNVAQLKAS 153 Query: 150 KLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLENFIQTDASI 209 + + + V + +G+ G G T G VSA +N N+ Q S+ Sbjct: 154 EAGSVRYETNADGSVNYSVLNLGD--GSGGTTRIGNVSA----AVNDTDAVNYAQLKRSV 207 Query: 210 NRGNS 214 N+ Sbjct: 208 EEANT 212 >1MBM-A nrPDB Length = 198 Score = 31.3 bits (69), Expect = 0.89, Method: Composition-based stats. Identities = 34/179 (18%), Positives = 64/179 (35%), Gaps = 23/179 (12%) Query: 89 EGLGSGVIINASKGYVL-TNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQN 147 G+G + + V+ T +HV+ +A ++++ D + D ++ Q + Sbjct: 12 SSYGTGSVWTRNNEVVVLTASHVVGRANMATLKIGD-AMLTLTFKKNGDFAEAVTTQSEL 70 Query: 148 PSKLTQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEGLEN--FIQT 205 P Q+ A + A G+ G++S G +Q Sbjct: 71 PGNWPQLHFAQPTT-GPASWCTATGD--------EEGLLSGEVCLAWTTSGDSGSAVVQG 121 Query: 206 DASI----NRGNSGGALLNL-NGELIGINTAILAP-----GGGSVGIGFAIPSNMARTL 254 DA + SG A + +G+L+G +T L+ G I IP N+ + Sbjct: 122 DAVVGVHTGSNTSGVAYVTTPSGKLLGADTVTLSSLSKHFTGPLTSIPKDIPDNIIADV 180 >5WDX-A nrPDB Length = 649 Score = 31.3 bits (69), Expect = 0.94, Method: Composition-based stats. Identities = 27/136 (19%), Positives = 50/136 (36%), Gaps = 11/136 (8%) Query: 212 GNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLAQQLIDFGEIKRG---- 267 G+SGG +L G ++G+ A + G + I F IP + + F + Sbjct: 155 GSSGGPVLCPRGHVVGLFRAAVCSRGVAKSIDF-IPVETL-DVVTRSPTFSDNSTPPAVP 212 Query: 268 -LLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFA 326 + K+ + V A +VL + S A + G ++ +G N Sbjct: 213 QTYQVGYLHAPTGSGKSTKVPVAYAAQGYKVLVLNPSVAATLGFGAYLSKAHGINPN--- 269 Query: 327 ELRSRIATTEPGTKVK 342 +R+ + T G + Sbjct: 270 -IRTGVRTVMTGEAIT 284 >1UEW-A nrPDB Length = 114 Score = 31.3 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 26/55 (47%), Gaps = 1/55 (1%) Query: 293 FVSEVLPGSGSAK-AGVKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLL 346 + ++ GS + + A +K GD I ++NG+ + + + G V L ++ Sbjct: 46 KIGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRII 100 >1V6B-A nrPDB Length = 118 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 18/55 (32%), Positives = 26/55 (47%), Gaps = 2/55 (3%) Query: 274 TEMSADIAKAFNLDVQRG-AFVSEVLPGSGSAK-AGVKAGDIITSLNGKPLNSFA 326 E S D+A +D G VS V G + + GV GD I ++NGK + + Sbjct: 26 KEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDYT 80 >5MV8-B nrPDB Length = 130 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 2/55 (3%) Query: 274 TEMSADIAKAFNLDVQRG-AFVSEVLPGSGSAK-AGVKAGDIITSLNGKPLNSFA 326 E S D+A +D G VS V + + G+ GD I ++NGK + + Sbjct: 38 KEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYT 92 >6C2N-A nrPDB Length = 203 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 1/44 (2%) Query: 212 GNSGGALLNLNGELIGINTAILAPGGGSVGIGFAIPSNMARTLA 255 G+SGG LL G +GI A ++ G + + F IP T Sbjct: 158 GSSGGPLLCPAGHAVGIFRAAVSTRGVAKAVAF-IPVESLETTM 200 >3EGH-C nrPDB Length = 170 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 35/87 (40%), Gaps = 2/87 (2%) Query: 263 EIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKP 321 E+++ G+ + + L+ + G FV V G + + G ++ D++ ++G Sbjct: 85 ELEKDSEGLGISIIGMGAGADMGLE-KLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTS 143 Query: 322 LNSFAELRSRIATTEPGTKVKLGLLRN 348 L + + +V+ + R Sbjct: 144 LVGVTQSFAASVLRNTKGRVRFMIGRE 170 >2SGA-A nrPDB Length = 181 Score = 30.9 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 28/146 (19%), Positives = 47/146 (32%), Gaps = 18/146 (12%) Query: 85 AQPFEGLGS----GVIIN-ASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSD 139 + GS G ++ + LT H N + SI G F G S+ Sbjct: 4 GEAITTGGSRCSLGFNVSVNGVAHALTAGHCTNISASWSIGTRTGTSFPNNDYGIIRHSN 63 Query: 140 IALLQIQNPSKLTQIAIADSDKLR------VGDFAVAVGNPFGLGQTATSGIVSALGRSG 193 A + + VG G+ GL + +G+ + + Sbjct: 64 PA-----AADGRVYLYNGSYQDITTAGNAFVGQAVQRSGSTTGLRSGSVTGLNATVNYGS 118 Query: 194 LNLEGLENFIQTDASINRGNSGGALL 219 + + IQT+ G+SGG+L Sbjct: 119 SGI--VYGMIQTNVCAQPGDSGGSLF 142 >5GT5-A nrPDB Length = 446 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 19/83 (22%), Positives = 32/83 (38%), Gaps = 2/83 (2%) Query: 246 IPSNMARTLAQQLIDFGEIKRGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSGSAK 305 I S MA +A + FG G I + + K+ DVQ ++ P + + Sbjct: 304 ITSGMAAAIASKGYKFGITSNG--AISTESNAVLVEKSVIKDVQYPVRNNQTDPTNATYT 361 Query: 306 AGVKAGDIITSLNGKPLNSFAEL 328 ++ D I SL+G + Sbjct: 362 GKIRVADTIYSLDGSSFRGSRDT 384 >5MRR-A nrPDB Length = 199 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 40/184 (21%), Positives = 70/184 (38%), Gaps = 19/184 (10%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPS 149 +G V A+KG+V T H + I F A++ +D A + + + Sbjct: 18 SVGFSVTRGATKGFV-TAGHCGGVGAIVRIGGTQVGSFAARVF---PGNDRAWVSVGSAH 73 Query: 150 KL---------TQIAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEG-L 199 L IAI S + +G G G G ++A + EG + Sbjct: 74 TLQGAVSNYSGGTIAIRGSAEAAIGAAVCRSGRTTGY----RCGNITAKNVTANYAEGAV 129 Query: 200 ENFIQTDASINRGNSGGALLNLNGELIGINTAI-LAPGGGSVGIGFAIPSNMARTLAQQL 258 Q +A + RG+SGG+ G+ G+ + + G + GI + S++ + L Sbjct: 130 RGLTQGNACMGRGDSGGSWFTSAGQAQGVMSGGNVQSNGNNCGIPASQRSSLFERVGPIL 189 Query: 259 IDFG 262 +G Sbjct: 190 SQYG 193 >3AQ1-B nrPDB Length = 500 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 35/75 (46%), Gaps = 6/75 (8%) Query: 249 NMARTLAQQLIDFGEIKRGL------LGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSG 302 N A + +I+ G++ G L ++ +E ++ + L V + A EV+P + Sbjct: 343 NDALHVVGVVIEDGKVVVGGGSSEVELSLRLSEYASTLKGREQLAVSKFAEALEVIPVAL 402 Query: 303 SAKAGVKAGDIITSL 317 + AG+ DI+ L Sbjct: 403 AENAGLDPIDIMVEL 417 >1GBE-A nrPDB Length = 198 Score = 30.5 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 68/183 (37%), Gaps = 18/183 (9%) Query: 90 GLGSGVIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQNPS 149 +G V A+KG+V T H I F A++ +D A + + + Sbjct: 18 SVGFSVTRGATKGFV-TAGHCGTVNATARIGGAVVGTFAARVF---PGNDRAWVSLTSAQ 73 Query: 150 KLTQ--------IAIADSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGRSGLNLEG-LE 200 L + + S + VG G G G ++A + EG + Sbjct: 74 TLLPRVANGSSFVTVRGSTEAAVGAAVCRSGRTTGYQ----CGTITAKNVTANYAEGAVR 129 Query: 201 NFIQTDASINRGNSGGALLNLNGELIGINT-AILAPGGGSVGIGFAIPSNMARTLAQQLI 259 Q +A RG+SGG+ + G+ G+ + + G + GI + S++ L L Sbjct: 130 GLTQGNACAGRGDSGGSWITSAGQAQGVMSGLNVQSNGNNCGIPASQRSSLFERLQPILS 189 Query: 260 DFG 262 +G Sbjct: 190 QYG 192 >2YT8-A nrPDB Length = 94 Score = 29.7 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 28/69 (40%), Gaps = 1/69 (1%) Query: 278 ADIAKAFNLDVQRGAFVSEVLPGSGSAKAGVKAGDIITSLNGKPLNSFAELRSRIATTEP 337 + V+ G + +L G + + G++ G I +NG+ + + R TE Sbjct: 16 PHAREQLGFCVEDGI-ICSLLRGGIAERGGIRVGHRIIEINGQSVVATPHARIIELLTEA 74 Query: 338 GTKVKLGLL 346 +V + + Sbjct: 75 YGEVHIKTM 83 >3FAO-A nrPDB Length = 213 Score = 29.7 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 31/167 (18%), Positives = 51/167 (30%), Gaps = 59/167 (35%) Query: 89 EGLGSG--VIINASKGYVLTNNHVINQAQKISIQLNDGREFDAKLIGSDDQSDIALLQIQ 146 +GSG I+ +T HV+ G F+ +++ D + D A I Sbjct: 27 SSMGSGGVFTIDGKI-KCVTAAHVLTGNS----ARVSGVGFN-QMLDFDVKGDFA---IA 77 Query: 147 NPSKLTQIAIA---------------DSDKLRVGDFAVAVGNPFGLGQTATSGIVSALGR 191 + +A S + G +GN F TA Sbjct: 78 DCPNWQGVAPKAQFCEDGWTGRAYWLTSSGVEPG----VIGNGFAFCFTAC--------- 124 Query: 192 SGLNLEGLENFIQTDASINRGNSGGALLNLNGELIGINTAILAPGGG 238 G++G ++ GEL+G++T GGG Sbjct: 125 --------------------GDAGSPVITEAGELVGVHTGSNKQGGG 151 >3U1J-B nrPDB Length = 191 Score = 29.3 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 18/34 (52%), Gaps = 2/34 (5%) Query: 211 RGNSGGALLNLNGELIGI--NTAILAPGGGSVGI 242 G SG ++N G+++G+ N + GG GI Sbjct: 141 PGTSGSPIINREGKVVGLYGNGVVTKNGGYVSGI 174 >2MX6-A nrPDB Length = 90 Score = 29.3 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 15/79 (18%), Positives = 29/79 (36%), Gaps = 14/79 (17%) Query: 266 RGLLGIKGTEMSADIAKAFNLDVQRGAFVSEVLPGSG-SAKAGVKAGDIITSLNGKPLNS 324 LGI S D G ++ ++ G +A ++ GD++ +N + Sbjct: 12 HHFLGISIVGQSNDRGDG-------GIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFEN 64 Query: 325 FAE------LRSRIATTEP 337 + LR ++ T P Sbjct: 65 MSNDDAVRVLREIVSQTGP 83 >1TXO-A nrPDB Length = 237 Score = 28.9 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 44/97 (45%), Gaps = 4/97 (4%) Query: 142 LLQIQNPSKLTQIAIADSDKLRVGDFAVAVGNPFGL---GQTATSGIVSALGRSGLNLEG 198 +L+ S + + D + G +A+ + G G+ A+ +++AL + G Sbjct: 4 VLRYAARSDRGLVRANNEDSVYAGARLLALADGMGGHAAGEVASQLVIAALAHLDDDEPG 63 Query: 199 LENFIQTDASINRGNSG-GALLNLNGELIGINTAILA 234 + + DA++ GNS A + + +L G+ T + A Sbjct: 64 GDLLAKLDAAVRAGNSAIAAQVEMEPDLEGMGTTLTA 100 >1V62-A nrPDB Length = 117 Score = 28.6 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 13/56 (23%), Positives = 25/56 (44%), Gaps = 1/56 (1%) Query: 292 AFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLL 346 + + P S ++G + GD I S++G + + L + KV+L +L Sbjct: 44 ITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHCSLLEATKLLASISEKVRLEIL 99 >4RTF-D nrPDB Length = 546 Score = 28.2 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 46/127 (36%), Gaps = 13/127 (10%) Query: 254 LAQQLIDFGEIKRGLLGIKGTEMSA--DIAKAF--NLDVQRGAFVSEVLPGSGSAKAGVK 309 +A I EI +L T M A D+ K + +G EV+ + +AGV Sbjct: 329 IADTGISVSEIDHVVLVGGSTRMPAVTDLVKELTGGKEPNKGVNPDEVVAVGAALQAGVL 388 Query: 310 AGDI--ITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR-------NGKPLEVEVTLDT 360 G++ + L+ PL+ E + + T + R + V++ + Sbjct: 389 KGEVKDVLLLDVTPLSLGIETKGGVMTRLIERNTTIPTKRSETFTTADDNQPSVQIQVYQ 448 Query: 361 STSSSAS 367 A+ Sbjct: 449 GEREIAA 455 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.128 0.315 Lambda K H 0.267 0.0390 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,286,863 Number of Sequences: 36641 Number of extensions: 544265 Number of successful extensions: 2117 Number of sequences better than 10.0: 140 Number of HSP's better than 10.0 without gapping: 155 Number of HSP's successfully gapped in prelim test: 76 Number of HSP's that attempted gapping in prelim test: 1664 Number of HSP's gapped (non-prelim): 309 length of query: 455 length of database: 10,336,785 effective HSP length: 100 effective length of query: 355 effective length of database: 6,672,685 effective search space: 2368803175 effective search space used: 2368803175 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 61 (28.2 bits)