BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P38919 (411 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2HYI-C nrPDB 851 0.0 3EIQ-A nrPDB 533 e-152 2VSX-A nrPDB 490 e-139 4BRW-A nrPDB 302 1e-82 5IVL-B nrPDB 296 9e-81 3BOR-A nrPDB 293 1e-79 5ZBZ-A nrPDB 290 7e-79 5ANR-B nrPDB 283 7e-77 3PEW-A nrPDB 281 3e-76 1QVA-A nrPDB 266 2e-71 1XTI-A nrPDB 263 8e-71 6B4I-E nrPDB 262 2e-70 3FHO-A nrPDB 254 6e-68 5SUQ-A nrPDB 252 2e-67 5SUP-A nrPDB 251 3e-67 1HV8-A nrPDB 244 4e-65 2I4I-A nrPDB 214 7e-56 6CZ5-A nrPDB 213 8e-56 4KBG-A nrPDB 212 2e-55 4D25-A nrPDB 209 1e-54 2DB3-A nrPDB 202 1e-52 5DTU-A nrPDB 202 3e-52 4NHO-A nrPDB 191 4e-49 3JCR-F nrPDB 187 1e-47 4LJY-A nrPDB 185 3e-47 4W7S-A nrPDB 177 1e-44 5ZWN-y nrPDB 176 2e-44 2Z0M-A nrPDB 170 1e-42 6CB1-p nrPDB 167 8e-42 5GJU-A nrPDB 163 1e-40 1VEC-A nrPDB 154 9e-38 2OXC-A nrPDB 152 3e-37 3I62-A nrPDB 150 8e-37 3SQW-A nrPDB 149 1e-36 6AIC-A nrPDB 144 5e-35 1T6N-A nrPDB 144 7e-35 2KBE-A nrPDB 142 3e-34 2GXQ-A nrPDB 135 3e-32 1Q0U-A nrPDB 127 1e-29 1WRB-A nrPDB 127 1e-29 3BER-A nrPDB 125 5e-29 3FHC-B nrPDB 123 2e-28 3FMO-B nrPDB 122 4e-28 5H1Y-A nrPDB 119 2e-27 5GVS-A nrPDB 117 8e-27 4PX9-A nrPDB 111 6e-25 3IUY-A nrPDB 106 2e-23 3LY5-A nrPDB 105 2e-23 3FE2-A nrPDB 104 8e-23 2PL3-A nrPDB 91 1e-18 3DKP-A nrPDB 82 3e-16 6CRM-A nrPDB 68 8e-12 1OYY-A nrPDB 64 8e-11 5LST-A nrPDB 60 2e-09 4CDG-A nrPDB 55 6e-08 1D9Z-A nrPDB 51 7e-07 4Q48-A nrPDB 51 1e-06 1WP9-A nrPDB 49 3e-06 5AGA-A nrPDB 49 5e-06 1GM5-A nrPDB 49 6e-06 2WWY-A nrPDB 48 7e-06 2NMV-A nrPDB 48 8e-06 5V9X-A nrPDB 48 8e-06 4GL2-A nrPDB 47 1e-05 5JCF-A nrPDB 46 3e-05 6G19-A nrPDB 45 6e-05 5TNU-A nrPDB 43 2e-04 5JBJ-A nrPDB 42 4e-04 2FWR-A nrPDB 42 7e-04 1C4O-A nrPDB 40 0.002 5LBA-B nrPDB 39 0.004 5LB8-A nrPDB 39 0.005 6BOG-A nrPDB 38 0.007 2P6R-A nrPDB 36 0.031 6DCR-A nrPDB 36 0.036 4NL8-A nrPDB 33 0.23 4ON9-A nrPDB 33 0.30 4A4Z-A nrPDB 33 0.30 4BPB-A nrPDB 33 0.32 3TBK-A nrPDB 33 0.33 4A36-A nrPDB 32 0.45 4A2Q-A nrPDB 32 0.54 6QKC-A nrPDB 32 0.56 4A2W-A nrPDB 32 0.56 6F4A-B nrPDB 30 2.6 2XSZ-D nrPDB 30 2.6 2BMF-A nrPDB 30 2.7 2JLW-A nrPDB 29 3.3 1YKS-A nrPDB 29 3.4 6BN7-A nrPDB 29 3.7 4L6H-A nrPDB 29 4.1 6FNP-B nrPDB 29 4.2 5N8S-A nrPDB 28 4.9 2WZQ-A nrPDB 28 4.9 2JGD-B nrPDB 28 8.1 4XGT-A nrPDB 28 8.4 >2HYI-C nrPDB Length = 413 Score = 851 bits (2199), Expect = 0.0, Method: Compositional matrix adjust. Identities = 411/411 (100%), Positives = 411/411 (100%) Query: 1 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK Sbjct: 1 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60 Query: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV Sbjct: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA Sbjct: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 Query: 181 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL Sbjct: 181 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240 Query: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA Sbjct: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300 Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360 Query: 361 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI Sbjct: 361 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 >3EIQ-A nrPDB Length = 414 Score = 533 bits (1373), Expect = e-152, Method: Compositional matrix adjust. Identities = 271/406 (66%), Positives = 328/406 (80%), Gaps = 1/406 (0%) Query: 7 MATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQ 66 M+ S +R R + M S ++ +FD M L E LLRGIYAYGFEKPSAIQQ Sbjct: 9 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 68 Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 RAI IKG DVIAQ+QSGTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK + Sbjct: 69 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 128 Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185 +ALGDYM CHACIGGTNV +++KL H++ GTPGRVFDM+ RR L + IKM V Sbjct: 129 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 188 Query: 186 LDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 LDEADEML++GFK+QIYD+++ L TQVVL+SAT+P ++LE+T KFM DPIRILVK++E Sbjct: 189 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 248 Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305 LTLEGI+QF++ VEREEWK DTLCDLY+TLTITQAVIF NT+RKVDWLTEKM +FTVS Sbjct: 249 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 308 Query: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365 +MHGDM QKER+ IM+EFRSG+SRVLI+TD+ ARG+DV QVSL+INYDLP NRE YIHRI Sbjct: 309 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 368 Query: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 GR GR+GRKGVAIN V +D R LRDIE +Y+T I+EMP+NVADLI Sbjct: 369 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 414 >2VSX-A nrPDB Length = 395 Score = 490 bits (1262), Expect = e-139, Method: Compositional matrix adjust. Identities = 240/372 (64%), Positives = 311/372 (83%), Gaps = 1/372 (0%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 FD M L E+LLRG++ YGFE+PSAIQQRAI II+G DV+AQ+QSGTGKT TFSI+ LQ Sbjct: 24 FDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQR 83 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159 +D V+ QAL+LAPTRELA+QIQK ++AL +M+++ HACIGGT+ ED L Q + Sbjct: 84 IDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ-I 142 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISA 219 V GTPGRVFD I+RR RT IKM +LDEADEML+ GFKEQIY ++ LPP TQVVL+SA Sbjct: 143 VVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSA 202 Query: 220 TLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQ 279 T+P+++LE+T KFM +P+RILVK+DELTLEGIKQF+V VE EE+K++ L DLYD++++TQ Sbjct: 203 TMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVNVEEEEYKYECLTDLYDSISVTQ 262 Query: 280 AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 AVIFCNT+RKV+ LT K+R FTVS+++ D+PQ+ER++IMKEFRSG+SR+LISTD+ AR Sbjct: 263 AVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERDTIMKEFRSGSSRILISTDLLAR 322 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQ 399 G+DV QVSL+INYDLP N+E YIHRIGR GR+GRKGVAINFV N+D+ +R++E++YSTQ Sbjct: 323 GIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVAINFVTNEDVGAMRELEKFYSTQ 382 Query: 400 IDEMPMNVADLI 411 I+E+P ++A L+ Sbjct: 383 IEELPSDIATLL 394 >4BRW-A nrPDB Length = 377 Score = 302 bits (774), Expect = 1e-82, Method: Compositional matrix adjust. Identities = 150/369 (40%), Positives = 226/369 (61%), Gaps = 2/369 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 TF+ L+ +LL GI+ GFEKPS IQ+ AI I GRD++A++++GTGKTA F I L+ Sbjct: 2 TFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLE 61 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158 + ++ + QALI+ PTRELA+Q + + LG + + C GGTN+ +DI +L+ H Sbjct: 62 KVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLNETVH 121 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 ++ GTPGRV D+ R+ + ++DEAD+ML++ FK I + +LPP Q +L S Sbjct: 122 ILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFS 181 Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 AT P + E +K + P I + +ELTL+GI Q++ VE E K L L+ L I Sbjct: 182 ATFPLTVDEFMDKHLHKPYEINL-MEELTLKGITQYYAFVE-ERQKLHCLNTLFSKLQIN 239 Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 QA+IFCN+ +V+ L +K+ + ++ H M Q+ER + EFR G R L+ +D+ Sbjct: 240 QAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLT 299 Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYST 398 RG+D+ V+++IN+D P E Y+HRIGRSGR+G G+AIN + +D L IEQ T Sbjct: 300 RGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGT 359 Query: 399 QIDEMPMNV 407 +I +P + Sbjct: 360 EIAAIPATI 368 >5IVL-B nrPDB Length = 429 Score = 296 bits (759), Expect = 9e-81, Method: Compositional matrix adjust. Identities = 146/365 (40%), Positives = 227/365 (62%), Gaps = 1/365 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 TF +GL +++++ I GFE+ + IQ + I ++ +DVI Q+Q+GTGKTA F I +++ Sbjct: 3 TFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPIVE 62 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158 +D++ QAL++APTRELA+Q+ + L +G V+ GG ++ IR L H Sbjct: 63 KVDVKNGAIQALVVAPTRELAIQVSEELYKIGAVKRVRVLPIYGGQDIERQIRALKKHPH 122 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 V+ GTPGR+ D I R +LR + +VLDEADEMLN GF E I + ++P Q +L S Sbjct: 123 VIVGTPGRIIDHINRGTLRLEHVHTVVLDEADEMLNMGFIEDIEAILSHVPAERQTLLFS 182 Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 AT+P I + +FM +P + VK E+T+ I+Q+++ V E+ KFD L L D Sbjct: 183 ATMPDPIRRIAERFMNEPELVKVKAKEMTVPNIQQYYLEV-HEKKKFDILTRLLDIQAPE 241 Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 A++F TKR+VD L E + + +HGD+ Q +R S++++F+ GA +L++TDV A Sbjct: 242 LAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAIEILVATDVAA 301 Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYST 398 RGLD+ V+ + N+D+P + E Y+HRIGR+GR G+ GVA+ FV +I L IE+ Sbjct: 302 RGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKTGVAMTFVTPREIGQLHHIERTTKR 361 Query: 399 QIDEM 403 +++ M Sbjct: 362 KMERM 366 >3BOR-A nrPDB Length = 237 Score = 293 bits (749), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 141/211 (66%), Positives = 173/211 (81%), Gaps = 1/211 (0%) Query: 35 DVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSI 94 ++ FD M L+E LLRGIYAYGFEKPSAIQQRAI IKG DVIAQ+QSGTGKTATF+I Sbjct: 27 EIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGTGKTATFAI 86 Query: 95 SVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD 154 S+LQ L+I+ +ETQAL+LAPTRELA QIQK +LALGDYM CHACIGGTNV +++KL Sbjct: 87 SILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNVRNEMQKLQ 146 Query: 155 Y-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213 H+V GTPGRVFDM+ RR L + IKM VLDEADEML++GFK+QIY++++ L + Q Sbjct: 147 AEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIFQKLNTSIQ 206 Query: 214 VVLISATLPHEILEMTNKFMTDPIRILVKRD 244 VVL+SAT+P ++LE+T KFM DPIRILVK++ Sbjct: 207 VVLLSATMPTDVLEVTKKFMRDPIRILVKKE 237 >5ZBZ-A nrPDB Length = 220 Score = 290 bits (742), Expect = 7e-79, Method: Compositional matrix adjust. Identities = 138/210 (65%), Positives = 171/210 (81%), Gaps = 1/210 (0%) Query: 35 DVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSI 94 ++ +FD M L E LLRGIYAYGFEKPSAIQQRAI IKG DVIAQ+QSGTGKTATF+I Sbjct: 11 EIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQSGTGKTATFAI 70 Query: 95 SVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD 154 S+LQ +++ ++ TQAL+LAPTRELA QIQK ++ALGDYM CHACIGGTNV +++KL Sbjct: 71 SILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGTNVRAEVQKLQ 130 Query: 155 Y-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213 H++ GTPGRVFDM+ RR L + IKM VLDEADEML++GFK+QIYD+++ L TQ Sbjct: 131 MEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYDIFQKLNSNTQ 190 Query: 214 VVLISATLPHEILEMTNKFMTDPIRILVKR 243 VVL+SAT+P ++LE+T KFM DPIRILVK+ Sbjct: 191 VVLLSATMPSDVLEVTKKFMRDPIRILVKK 220 >5ANR-B nrPDB Length = 378 Score = 283 bits (725), Expect = 7e-77, Method: Compositional matrix adjust. Identities = 139/369 (37%), Positives = 233/369 (63%), Gaps = 3/369 (0%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F+ L+ +LL GI+ G+EKPS IQ+ +I + GRD++A++++GTGK+ + I +L+ Sbjct: 7 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 66 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGEDIRKLDYGQH 158 LD++ QA+++ PTRELA+Q+ + + + +M + A GGTN+ +DI +LD H Sbjct: 67 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 126 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 VV TPGR+ D+I++ + ++M+VLDEAD++L++ F + + D+ LP Q++L S Sbjct: 127 VVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYS 186 Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 AT P + + N + P I + +ELTL+G+ Q++ V E K L L+ L I Sbjct: 187 ATFPLSVQKFMNSHLQKPYEINLM-EELTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQIN 244 Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 Q++IFCN+ ++V+ L +K+ + ++ +H M Q+ R + +FR+G R L+ TD++ Sbjct: 245 QSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFT 304 Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYST 398 RG+D+ V+++IN+D P E Y+HRIGRSGR+G G+AIN + DD L+ IE+ T Sbjct: 305 RGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGT 364 Query: 399 QIDEMPMNV 407 +I +P N+ Sbjct: 365 EIKPIPSNI 373 >3PEW-A nrPDB Length = 395 Score = 281 bits (720), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 148/368 (40%), Positives = 237/368 (64%), Gaps = 14/368 (3%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96 +FD +GL +LL+GIYA F+KPS IQ+RA+ ++ R++IAQSQSGTGKTA FS+++ Sbjct: 6 SFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTM 65 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYG 156 L ++ + QA+ LAP+RELA Q + + +G + + + + E ++++ Sbjct: 66 LTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIV--PDSFEKNKQIN-- 121 Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVV 215 V+ GTPG V D++RR+ ++ + IK+ VLDEAD ML++ G +Q V R+LP TQ+V Sbjct: 122 AQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLV 181 Query: 216 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275 L SAT + + K + + + ++ +E+ ++ IKQ ++ + E KFD L +LY + Sbjct: 182 LFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELYGVM 241 Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335 TI ++IF TK+ + L K++ VS +HGD+ +ER+ ++ +FR G S+VLI+T+ Sbjct: 242 TIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLITTN 301 Query: 336 VWARGLDVPQVSLIINYDLPN------NRELYIHRIGRSGRYGRKGVAINFVKN-DDIRI 388 V ARG+D+P VS+++NYDLP + YIHRIGR+GR+GRKGVAI+FV + + I Sbjct: 302 VLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNSFNI 361 Query: 389 LRDIEQYY 396 L I++Y+ Sbjct: 362 LSAIQKYF 369 >1QVA-A nrPDB Length = 223 Score = 266 bits (679), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 128/202 (63%), Positives = 160/202 (79%), Gaps = 1/202 (0%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 FD M L E LLRG++ YGFE+PSAIQQRAI II+G DV+AQ+QSGTGKT TFSI+ LQ Sbjct: 23 FDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHDVLAQAQSGTGKTGTFSIAALQR 82 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159 +D V+ QAL+LAPTRELA+QIQK ++AL +M+++ HACIGGT+ ED L Q + Sbjct: 83 IDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKVHACIGGTSFVEDAEGLRDAQ-I 141 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISA 219 V GTPGRVFD I+RR RT IKM +LDEADEML+ GFKEQIY ++ LPP TQVVL+SA Sbjct: 142 VVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGFKEQIYQIFTLLPPTTQVVLLSA 201 Query: 220 TLPHEILEMTNKFMTDPIRILV 241 T+P+++LE+T KFM +P+RILV Sbjct: 202 TMPNDVLEVTTKFMRNPVRILV 223 >1XTI-A nrPDB Length = 391 Score = 263 bits (673), Expect = 8e-71, Method: Compositional matrix adjust. Identities = 141/370 (38%), Positives = 219/370 (59%), Gaps = 6/370 (1%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +LLR I GFE PS +Q I Q I G DV+ Q++SG GKTA F ++ LQ Sbjct: 10 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 69 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYG-Q 157 L+ + L++ TRELA QI K YM NV+ GG ++ +D L Sbjct: 70 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 129 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVL 216 H+V GTPGR+ + R +SL + IK +LDE D+ML + + + +++R P QV++ Sbjct: 130 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 189 Query: 217 ISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275 SATL EI + KFM DP+ I V + +LTL G++Q++V ++ E K L DL D L Sbjct: 190 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 248 Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335 Q VIF + ++ L + + E NF ++H MPQ+ER S ++F+ R+L++T+ Sbjct: 249 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 308 Query: 336 VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDIEQ 394 ++ RG+D+ +V++ NYD+P + + Y+HR+ R+GR+G KG+AI FV + +D +IL D++ Sbjct: 309 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 368 Query: 395 YYSTQIDEMP 404 + I E+P Sbjct: 369 RFEVNISELP 378 >6B4I-E nrPDB Length = 430 Score = 262 bits (669), Expect = 2e-70, Method: Compositional matrix adjust. Identities = 142/381 (37%), Positives = 237/381 (62%), Gaps = 23/381 (6%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII--KGRDVIAQSQSGTGKTATFSISV 96 +F+ + L+ LL+G+YA GF +PS IQ+ A+ ++ +++IAQSQSGTGKTA F +++ Sbjct: 44 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 103 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDY 155 L ++ + Q L L+PT ELA+Q K + +G Y ++ + G KL+ Sbjct: 104 LSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLER 156 Query: 156 GQ----HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLP 209 GQ +V GTPG V D + + + + IK+ VLDEAD M+ +G ++Q + R LP Sbjct: 157 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 216 Query: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC 269 Q++L SAT + + K + DP I +KR+E TL+ IKQ++V + KF LC Sbjct: 217 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEETLDTIKQYYVLCSSRDEKFQALC 276 Query: 270 DLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASR 329 +LY +TI QA+IFC+T++ WL ++ + V+ + G+M ++R ++++ FR G + Sbjct: 277 NLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQVALLSGEMMVEQRAAVIERFREGKEK 336 Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNR------ELYIHRIGRSGRYGRKGVAINFVKN 383 VL++T+V ARG+DV QVS++IN+DLP ++ E Y+HRIGR+GR+G++G+A+N V + Sbjct: 337 VLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPDNETYLHRIGRTGRFGKRGLAVNMVDS 396 Query: 384 -DDIRILRDIEQYYSTQIDEM 403 + IL I+++++ +I+ + Sbjct: 397 KHSMNILNRIQEHFNKKIERL 417 >3FHO-A nrPDB Length = 508 Score = 254 bits (648), Expect = 6e-68, Method: Compositional matrix adjust. Identities = 139/353 (39%), Positives = 218/353 (61%), Gaps = 14/353 (3%) Query: 64 IQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQ 121 IQ++A+ ++ R++I QSQSGTGKTA F++++L +D V + QA+ LAP+RELA Q Sbjct: 145 IQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELARQ 204 Query: 122 IQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAI 181 I + +G Y V+ G + K+D +V GTPG V D+++RR L R I Sbjct: 205 IMDVVTEMGKYTEVK--TAFGIKDSVPKGAKID--AQIVIGTPGTVMDLMKRRQLDARDI 260 Query: 182 KMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240 K+ VLDEAD ML++ G +Q + LP TQ+VL SAT + + +F + I Sbjct: 261 KVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPNANEIR 320 Query: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300 +K +EL++EGIKQ ++ + EE K++ L +LY LTI Q++IFC K + + +M Sbjct: 321 LKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIARRMTAD 380 Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNR-- 358 TV+ + G++ +R++IM FR G S+VL++T+V ARG+DV QV+L++NYD+P ++ Sbjct: 381 GHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDMPLDQAG 440 Query: 359 ----ELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDIEQYYSTQIDEMPMN 406 + Y+HRIGR+GR+GR GV+INFV + + I++Y+ I +P + Sbjct: 441 RPDPQTYLHRIGRTGRFGRVGVSINFVHDKKSWEEMNAIQEYFQRPITRVPTD 493 >5SUQ-A nrPDB Length = 446 Score = 252 bits (643), Expect = 2e-67, Method: Compositional matrix adjust. Identities = 136/372 (36%), Positives = 218/372 (58%), Gaps = 8/372 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +L R I GFE PS +QQ I Q I G DV+ Q++SG GKTA F +S LQ Sbjct: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGED---IRKLDY 155 LD E +++ RELA QI+ L YM +V+ GGT + +D ++ D Sbjct: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQV 214 H+V TPGR+ ++R + + +K V+DE D++L + + + +++R P QV Sbjct: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 Query: 215 VLISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYD 273 ++ SATL EI + +F+ +P+ I V + +LTL G++Q+++ +E E K L L D Sbjct: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLD 302 Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333 L Q +IF + + + LT+ + +NF ++HG M Q+ER + K F+ R+ +S Sbjct: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 Query: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDI 392 TDV+ RG+D+ +++L INYDL N + Y+HR+GR+GR+G KG+AI+FV + +D +L I Sbjct: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 Query: 393 EQYYSTQIDEMP 404 ++ + +I E P Sbjct: 423 QERFDVKIAEFP 434 >5SUP-A nrPDB Length = 390 Score = 251 bits (642), Expect = 3e-67, Method: Compositional matrix adjust. Identities = 136/372 (36%), Positives = 218/372 (58%), Gaps = 8/372 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +L R I GFE PS +QQ I Q I G DV+ Q++SG GKTA F +S LQ Sbjct: 8 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 67 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGED---IRKLDY 155 LD E +++ RELA QI+ L YM +V+ GGT + +D ++ D Sbjct: 68 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 127 Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQV 214 H+V TPGR+ ++R + + +K V+DE D++L + + + +++R P QV Sbjct: 128 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 187 Query: 215 VLISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYD 273 ++ SATL EI + +F+ +P+ I V + +LTL G++Q+++ +E E K L L D Sbjct: 188 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLEERE-KNRKLAQLLD 246 Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333 L Q +IF + + + LT+ + +NF ++HG M Q+ER + K F+ R+ +S Sbjct: 247 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 306 Query: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDI 392 TDV+ RG+D+ +++L INYDL N + Y+HR+GR+GR+G KG+AI+FV + +D +L I Sbjct: 307 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 366 Query: 393 EQYYSTQIDEMP 404 ++ + +I E P Sbjct: 367 QERFDVKIAEFP 378 >1HV8-A nrPDB Length = 367 Score = 244 bits (623), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 131/366 (35%), Positives = 215/366 (58%), Gaps = 9/366 (2%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGR-DVIAQSQSGTGKTATFSISVL 97 F+ + L +++L I GFEKP+ IQ + I + +++AQ+++G+GKTA+F+I ++ Sbjct: 7 NFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLI 66 Query: 98 QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ 157 + ++ + +A+IL PTRELA+Q+ + +L N++ GG + I+ L Sbjct: 67 ELVN-ENNGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQIKALK-NA 124 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLI 217 ++V GTPGR+ D I R +L + +K +LDEADEMLN GF + + + +++L Sbjct: 125 NIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNACNKDKRILLF 184 Query: 218 SATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI 277 SAT+P EIL + K+M D I K + I+Q +V V E +F+ LC L Sbjct: 185 SATMPREILNLAKKYMGDYSFIKAKINA----NIEQSYVEVNENE-RFEALCRLLKNKEF 239 Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337 ++FC TKR L +R+ F ++HGD+ Q +RE +++ F+ R+LI+TDV Sbjct: 240 Y-GLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRILIATDVM 298 Query: 338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYS 397 +RG+DV ++ +INY LP N E Y+HRIGR+GR G+KG AI+ + + + LR IE+ Sbjct: 299 SRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKKLRYIERAMK 358 Query: 398 TQIDEM 403 +I ++ Sbjct: 359 LKIKKL 364 >2I4I-A nrPDB Length = 417 Score = 214 bits (544), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 137/381 (35%), Positives = 207/381 (54%), Gaps = 32/381 (8%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 +F + + E ++ I + +P+ +Q+ AI I + RD++A +Q+G+GKTA F + +L Sbjct: 16 SFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILS 75 Query: 99 CL---------------DIQVRETQ---ALILAPTRELAVQIQKGLLALGDYMNVQCHAC 140 + R Q +L+LAPTRELAVQI + V+ Sbjct: 76 QIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVV 135 Query: 141 IGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQ 200 GG ++G+ IR L+ G H++ TPGR+ DM+ R + K LVLDEAD ML+ GF+ Q Sbjct: 136 YGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQ 195 Query: 201 IYDVYRY--LPP--ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFV 256 I + +PP ++ SAT P EI + F+ + I + V R T E I Q V Sbjct: 196 IRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVV 255 Query: 257 AVEREEWKFDTLCDLY-----DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDM 311 VE E K L DL D+LT+ +F TK+ D L + + + +S+HGD Sbjct: 256 WVE-ESDKRSFLLDLLNATGKDSLTL----VFVETKKGADSLEDFLYHEGYACTSIHGDR 310 Query: 312 PQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRY 371 Q++RE + +FRSG S +L++T V ARGLD+ V +IN+DLP++ E Y+HRIGR+GR Sbjct: 311 SQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRV 370 Query: 372 GRKGVAINFVKNDDIRILRDI 392 G G+A +F +I I +D+ Sbjct: 371 GNLGLATSFFNERNINITKDL 391 >6CZ5-A nrPDB Length = 480 Score = 213 bits (543), Expect = 8e-56, Method: Compositional matrix adjust. Identities = 142/406 (34%), Positives = 214/406 (52%), Gaps = 42/406 (10%) Query: 24 TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73 T + FE +++ V T F + + E ++ I + +P+ +Q+ AI I Sbjct: 29 TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIK 88 Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCL---------------DIQVRETQ---ALILAPT 115 + RD++A +Q+G GKTA F + +L + R Q +L+LAPT Sbjct: 89 EKRDLMACAQTGCGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPT 148 Query: 116 RELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRS 175 RELAVQI + V+ GG ++G+ IR L+ G H++ TPGR+ DM+ R Sbjct: 149 RELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK 208 Query: 176 LRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTNK 231 + K LVLDEAD ML+ GF+ QI + +PP ++ SAT P EI + Sbjct: 209 IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARD 268 Query: 232 FMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLY-----DTLTITQAVIFCNT 286 F+ + I + V R T E I Q V VE E K L DL D+LT+ +F T Sbjct: 269 FLDEYIFLAVGRVGSTSENITQKVVWVE-ESDKRSFLLDLLNATGKDSLTL----VFVET 323 Query: 287 KRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQV 346 K+ D L + + + +S+HGD Q++RE + +FRSG S +L++T V ARGLD+ V Sbjct: 324 KKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNV 383 Query: 347 SLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392 +IN+DLP++ E Y+HRIGR+GR G G+A +F +I I +D+ Sbjct: 384 KHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDL 429 >4KBG-A nrPDB Length = 365 Score = 212 bits (540), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 117/328 (35%), Positives = 189/328 (57%), Gaps = 10/328 (3%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ ++L ++ G P+ IQ A+ ++G+D+I Q+++GTGKT F++ + + Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 100 LDI---QVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYG 156 L + R+ +AL+L PTRELA+Q+ L A+ ++ V A GGT G+ L G Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVV--AVYGGTGYGKQKEALLRG 120 Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVL 216 V TPGR D +R+ L +++ VLDEADEML+ GF+E++ + PP+ Q +L Sbjct: 121 ADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLL 180 Query: 217 ISATLPHEILEMTNKFMTDPIRILVKRDE-LTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275 SATLP + ++M +P+ I V +DE +T E ++ A R + + L DL Sbjct: 181 FSATLPSWAKRLAERYMKNPVLINVIKDEPVTYE--EEAVPAPVR--GRLEVLSDLLYVA 236 Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335 + +A++F TK + + + + + ++HGD+ Q ERE ++ FR G RVL++TD Sbjct: 237 SPDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRVLVATD 296 Query: 336 VWARGLDVPQVSLIINYDLPNNRELYIH 363 V ARGLD+PQV L+++Y LP+ E Y H Sbjct: 297 VAARGLDIPQVDLVVHYRLPDRAEAYQH 324 >4D25-A nrPDB Length = 434 Score = 209 bits (533), Expect = 1e-54, Method: Compositional matrix adjust. Identities = 121/374 (32%), Positives = 207/374 (55%), Gaps = 23/374 (6%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 +F+T LR+ +L + G+ KP+ IQ+ AI I+ GRD++ +Q+G+GKTA F + ++ Sbjct: 51 SFETANLRKYVLDNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIIN 110 Query: 99 CL---------DIQVRETQALILAPTRELAVQI--QKGLLALGDYMNVQCHACIGGTNVG 147 L + + Q +I++PTREL +QI + + G + V GGT V Sbjct: 111 MLLQDPKDLISENGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAV--AYGGTAVR 168 Query: 148 EDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY 207 + G H++ TPGR+ D + R + +++ +VLD+AD ML+ GF I + Sbjct: 169 HQGDNIARGCHILVATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMM-- 226 Query: 208 LPPAT------QVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVERE 261 L P Q ++ SAT P +I + +F+ + + + V ++Q F+ V + Sbjct: 227 LHPTMVETTKRQTLMFSATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKY 286 Query: 262 EWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK 321 E K ++L L + + ++F TKR D++ + E SS+HGD Q+ERE ++ Sbjct: 287 E-KRNSLKQLIEENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQ 345 Query: 322 EFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV 381 F+SG +L++T V ARGLD+ V +++NYDLP + + Y+HRIGR+GR G +G A++F Sbjct: 346 NFKSGKHCILVATAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFY 405 Query: 382 KND-DIRILRDIEQ 394 +D D+ ++ D+ + Sbjct: 406 DSDQDLALVADLSK 419 >2DB3-A nrPDB Length = 434 Score = 202 bits (515), Expect = 1e-52, Method: Compositional matrix adjust. Identities = 119/353 (33%), Positives = 196/353 (55%), Gaps = 19/353 (5%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F + LR+ ++ + G++ P+ IQ+ +I I GRD++A +Q+G+GKTA F + +L Sbjct: 58 FTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQTGSGKTAAFLLPILSK 117 Query: 100 L-----DIQVRETQALILAPTRELAVQI--QKGLLALGDYMNVQCHACIGGTNVGEDIRK 152 L ++++ Q +I++PTRELA+QI + A Y+ + GGT+ Sbjct: 118 LLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGI--VYGGTSFRHQNEC 175 Query: 153 LDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP--P 210 + G HVV TPGR+ D + R + + +VLDEAD ML+ GF E + + ++ P Sbjct: 176 ITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSEDMRRIMTHVTMRP 235 Query: 211 ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCD 270 Q ++ SAT P EI M +F+ + + + + +KQ V K+ Sbjct: 236 EHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYEVN----KYAKRSK 291 Query: 271 LYDTLTITQA---VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGA 327 L + L+ QA ++F TKR D+L + E F +S+HGD Q +RE +++F++G+ Sbjct: 292 LIEILS-EQADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQREQALRDFKNGS 350 Query: 328 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 380 +VLI+T V +RGLD+ + +INYD+P+ + Y+HRIGR+GR G G A +F Sbjct: 351 MKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRATSF 403 >5DTU-A nrPDB Length = 475 Score = 202 bits (513), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 118/401 (29%), Positives = 213/401 (53%), Gaps = 35/401 (8%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 ++ GL LL +Y G+++P+ IQ+ AI ++ RD+I + +G+GKTA F + +L Sbjct: 43 NWEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVTGSGKTAAFLLPLLV 102 Query: 99 CLDIQVRETQ--------ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDI 150 + T+ ALILAPTREL QI+ D + + +GG ++ E Sbjct: 103 YISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPLGFTVVSIVGGHSLEEQA 162 Query: 151 RKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP- 209 L G ++ TPGR+ D I RR L +++DEAD M+++GF+E + + LP Sbjct: 163 FALRNGAEIIVATPGRLVDCIERRLLVFSQCCYVIMDEADRMIDQGFEEPLTKILDALPV 222 Query: 210 ----PAT--------------------QVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 P T Q ++ +AT+P + ++ K++ P + + Sbjct: 223 SNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKKYLRRPAIVTIGNAG 282 Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVI-FCNTKRKVDWLTEKMREANFTV 304 ++ ++Q + E+ + L ++ ++ +I F N KR + + + ++ F+ Sbjct: 283 EAVDTVEQRVEFIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRNCEMVAKDIKSWGFST 342 Query: 305 SSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHR 364 ++HG Q++RE+ + R+G + +L++TD+ RG+DVP VSL++N+++P+ E Y HR Sbjct: 343 VTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLVVNFNMPSTIEAYTHR 402 Query: 365 IGRSGRYGRKGVAINFVKNDDIRILRDIEQYYS-TQIDEMP 404 IGR+GR G+ GVAI F+ N+D ++ D++Q S + I ++P Sbjct: 403 IGRTGRAGKSGVAITFLGNEDADVMYDLKQIISKSSISKVP 443 >4NHO-A nrPDB Length = 488 Score = 191 bits (486), Expect = 4e-49, Method: Compositional matrix adjust. Identities = 119/408 (29%), Positives = 211/408 (51%), Gaps = 39/408 (9%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 ++ L +L I G+++P+ IQ++AI ++ RD+I +++G+GKTA F I +L Sbjct: 60 SWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLV 119 Query: 99 CLDI-----QVRETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGED 149 + ++ E+ A+ILAPTRELA QI++ + G + ++ A IGG + + Sbjct: 120 WITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQ 179 Query: 150 IRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP 209 +L G +V TPGR+ D++ R L +VLDEAD M++ GF+ + + ++P Sbjct: 180 GFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMP 239 Query: 210 -----PAT---------------------QVVLISATLPHEILEMTNKFMTDPIRILVKR 243 P T Q V+ +AT+P + + ++ P + + Sbjct: 240 VSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGS 299 Query: 244 DELTLEGIKQ-FFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANF 302 E ++Q F+ E E+ K L + + +IF N K+ D L + + + + Sbjct: 300 AGKPHERVEQKVFLMSESEKRK--KLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGY 357 Query: 303 TVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYI 362 ++HG Q++RE + ++GA +L++TDV RG+D+ VS+++NYD+ N E YI Sbjct: 358 NACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYI 417 Query: 363 HRIGRSGRYGRKGVAINFVKNDDIRILRDIEQ-YYSTQIDEMPMNVAD 409 HRIGR+GR G+ GVAI F+ +D + +++Q + + P +A+ Sbjct: 418 HRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELAN 465 >3JCR-F nrPDB Length = 820 Score = 187 bits (474), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 116/382 (30%), Positives = 202/382 (52%), Gaps = 38/382 (9%) Query: 49 LLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDI-----Q 103 +L I G+++P+ IQ++AI ++ RD+I +++G+GKTA F I +L + + Sbjct: 402 ILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAETGSGKTAAFLIPLLVWITTLPKIDR 461 Query: 104 VRETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159 + E+ A+ILAPTRELA QI++ + G + ++ A IGG + + +L G + Sbjct: 462 IEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGIRTVAVIGGISREDQGFRLRMGCEI 521 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLP-----PAT-- 212 V TPGR+ D++ R L +VLDEAD M++ GF+ + + ++P P T Sbjct: 522 VIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDMGFEPDVQKILEHMPVSNQKPDTDE 581 Query: 213 -------------------QVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQ 253 Q V+ +AT+P + + ++ P + + E ++Q Sbjct: 582 AEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLARSYLRRPAVVYIGSAGKPHERVEQ 641 Query: 254 -FFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMP 312 F+ E E+ K L + + +IF N K+ D L + + + + ++HG Sbjct: 642 KVFLMSESEKRK--KLLAILEQGFDPPIIIFVNQKKGCDVLAKSLEKMGYNACTLHGGKG 699 Query: 313 QKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYG 372 Q++RE + ++GA +L++TDV RG+D+ VS+++NYD+ N E YIHRIGR+GR G Sbjct: 700 QEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMVVNYDMAKNIEDYIHRIGRTGRAG 759 Query: 373 RKGVAINFVKNDDIRILRDIEQ 394 + GVAI F+ +D + +++Q Sbjct: 760 KSGVAITFLTKEDSAVFYELKQ 781 >4LJY-A nrPDB Length = 493 Score = 185 bits (470), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 111/359 (30%), Positives = 190/359 (52%), Gaps = 30/359 (8%) Query: 58 FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQ----VRET--QALI 111 F + IQ +A+ I+ GRDVI S++G+GKT ++ + +L+ + Q ET LI Sbjct: 71 FGSLTPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLI 130 Query: 112 LAPTRELAVQIQKGLLALGDY-MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDM 170 LAPTRELA+QI + + + +++ C GG+ + + I L G +V TPGR D+ Sbjct: 131 LAPTRELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDI 190 Query: 171 IR---RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILE 227 + + L T+ I +V+DEAD + + GF+ QI + + + P Q VL SAT P+++ Sbjct: 191 LTLNDGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRS 250 Query: 228 MTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDL-------YDTLTI--- 277 + + PI I + + E +KQ F E+ KFD L L +D + Sbjct: 251 FAVRVLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSEND 310 Query: 278 ----------TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGA 327 +A+IF +++ D++++K+ A ++H P +ER +++F+ Sbjct: 311 GQSSDVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREK 370 Query: 328 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDI 386 + +L+ T+V +RGL+VP+VSL+I Y+ Y+H GR+ R R G AI + +D++ Sbjct: 371 NSILLCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDEL 429 >4W7S-A nrPDB Length = 463 Score = 177 bits (448), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 125/395 (31%), Positives = 205/395 (51%), Gaps = 44/395 (11%) Query: 32 EEVDVTPTFDTMGLREDLLRGIYA-YGFEKPSAIQQRAIKQII---KGRDVIAQSQSGTG 87 EE+++ P DLLR I F P+ IQ+ I + + RD + + +G+G Sbjct: 50 EELNIIP--------RDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSG 101 Query: 88 KTATFSISVL----------QCLDIQVRETQALILAPTRELAVQIQKGLLAL----GDYM 133 KT F I +L L I + +ALILAPTREL QIQK + Sbjct: 102 KTLAFVIPILIKMSRSPPRPPSLKI-IDGPKALILAPTRELVQQIQKETQKVTKIWSKES 160 Query: 134 NVQCH--ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE 191 N C + +GG ++ E L G ++ TPGR+ D + L + ++ LVLDEAD+ Sbjct: 161 NYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADK 220 Query: 192 MLNKGFKEQIYDVYRYLPPAT------QVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 M++ GF++Q+ ++ + Q ++ +AT+ I ++ +M P+ + + Sbjct: 221 MIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIGVET 280 Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDL---YDTLTITQAVIFCNTKRKVDWLTEKM-REAN 301 + I+Q + +E KF L + YD I IF N K+ DWL EK +E N Sbjct: 281 GSEPLIQQVVEYADNDEDKFKKLKPIVAKYDPPII----IFINYKQTADWLAEKFQKETN 336 Query: 302 FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELY 361 V+ +HG Q++RE ++ FR+ +++I+T+V ARGLD+P VSL++N+ + + Y Sbjct: 337 MKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDY 396 Query: 362 IHRIGRSGRYGRKGVAINFVK-NDDIRILRDIEQY 395 IHRIGR+GR +G A++FV +D ++R++ +Y Sbjct: 397 IHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKY 431 >5ZWN-y nrPDB Length = 588 Score = 176 bits (445), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 125/395 (31%), Positives = 205/395 (51%), Gaps = 44/395 (11%) Query: 32 EEVDVTPTFDTMGLREDLLRGIYA-YGFEKPSAIQQRAIKQII---KGRDVIAQSQSGTG 87 EE+++ P DLLR I F P+ IQ+ I + + RD + + +G+G Sbjct: 175 EELNIIP--------RDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVASTGSG 226 Query: 88 KTATFSISVL----------QCLDIQVRETQALILAPTRELAVQIQKGLLAL----GDYM 133 KT F I +L L I + +ALILAPTREL QIQK + Sbjct: 227 KTLAFVIPILIKMSRSPPRPPSLKI-IDGPKALILAPTRELVQQIQKETQKVTKIWSKES 285 Query: 134 NVQCH--ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE 191 N C + +GG ++ E L G ++ TPGR+ D + L + ++ LVLDEAD+ Sbjct: 286 NYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLDEADK 345 Query: 192 MLNKGFKEQIYDVYRYLPPAT------QVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 M++ GF++Q+ ++ + Q ++ +AT+ I ++ +M P+ + + Sbjct: 346 MIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATIGVET 405 Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDL---YDTLTITQAVIFCNTKRKVDWLTEKM-REAN 301 + I+Q + +E KF L + YD I IF N K+ DWL EK +E N Sbjct: 406 GSEPLIQQVVEYADNDEDKFKKLKPIVAKYDPPII----IFINYKQTADWLAEKFQKETN 461 Query: 302 FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELY 361 V+ +HG Q++RE ++ FR+ +++I+T+V ARGLD+P VSL++N+ + + Y Sbjct: 462 MKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDDY 521 Query: 362 IHRIGRSGRYGRKGVAINFVK-NDDIRILRDIEQY 395 IHRIGR+GR +G A++FV +D ++R++ +Y Sbjct: 522 IHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKY 556 >2Z0M-A nrPDB Length = 337 Score = 170 bits (430), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 107/342 (31%), Positives = 181/342 (52%), Gaps = 21/342 (6%) Query: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104 + E + + I GF+ + +Q + I +++G++V+ ++++G+GKTA ++I +L+ Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 105 RETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTP 164 ++L++ PTREL Q+ + +G YM+ + GG I ++ VVA TP Sbjct: 56 -GMKSLVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRVRNADIVVA-TP 113 Query: 165 GRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHE 224 GR+ D+ + + + +++++DEAD M GF + I + L SAT+P E Sbjct: 114 GRLLDLWSKGVIDLSSFEIVIIDEADLMFEMGFIDDIKIILAQTSNRKITGLFSATIPEE 173 Query: 225 ILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEW--KFDTLCDLYDTLTITQAVI 282 I ++ F+T+ I + L ++ FV V +++W K L + D ++ Sbjct: 174 IRKVVKDFITNYEEI---EACIGLANVEHKFVHV-KDDWRSKVQALRENKDK----GVIV 225 Query: 283 FCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLD 342 F T+ +V L A + GD+PQ R + FR G +LI+TDV +RGLD Sbjct: 226 FVRTRNRVAKLVRLFDNA----IELRGDLPQSVRNRNIDAFREGEYDMLITTDVASRGLD 281 Query: 343 VPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND 384 +P V +IN+D P + YIHRIGR+GR GRKG AI F+ N+ Sbjct: 282 IPLVEKVINFDAPQDLRTYIHRIGRTGRMGRKGEAITFILNE 323 >6CB1-p nrPDB Length = 505 Score = 167 bits (423), Expect = 8e-42, Method: Compositional matrix adjust. Identities = 117/404 (28%), Positives = 210/404 (51%), Gaps = 21/404 (5%) Query: 7 MATSGSARKRLLKEEDMTKV-EFETSEEVDVTP---------TFDTMGLREDLLRGIYAY 56 MAT + R R + + V E TS++ + P F+ + L + L+ I Sbjct: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 Query: 57 GFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATF---SISVLQCLDIQVRE-TQALIL 112 GF +++Q R I ++ GRDV+ +++G+GKT F +I +L L + R T +++ Sbjct: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172 PTRELA+QI L ++ + IGG N ++ KL G +++ TPGR+ D ++ Sbjct: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 Query: 173 R-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT-QVVLISATLPHEILEMTN 230 + + +K L++DEAD +L GF++++ + + LP Q +L SAT ++ ++ Sbjct: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 Query: 231 -KFMTDP--IRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287 P I ++ + D T +G++Q +V + ++ +F L + ++F ++ Sbjct: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDK-RFLLLFSFLKRNQKKKIIVFLSSC 299 Query: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347 V + E + + V +HG Q++R + EF + +LI TDV ARGLD+P V Sbjct: 300 NSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVD 359 Query: 348 LIINYDLPNNRELYIHRIGRSGRYGR-KGVAINFVKNDDIRILR 390 II +D P++ YIHR+GR+ R + KG ++ F+ +++ LR Sbjct: 360 WIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLR 403 >5GJU-A nrPDB Length = 205 Score = 163 bits (412), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 83/199 (41%), Positives = 118/199 (59%), Gaps = 1/199 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 TF +GL+ +L + G+EKPS IQ I ++ GRDV+ +Q+G+GKTA FS+ +LQ Sbjct: 2 TFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQ 61 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQ 157 LD +++ Q L+LAPTRELAVQ+ + + +M V A GG +R L G Sbjct: 62 NLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGP 121 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLI 217 +V GTPGR+ D ++R +L + LVLDEADEML GF E + + +P Q L Sbjct: 122 QIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTALF 181 Query: 218 SATLPHEILEMTNKFMTDP 236 SAT+P I +T +FM +P Sbjct: 182 SATMPEAIRRITRRFMKEP 200 >1VEC-A nrPDB Length = 206 Score = 154 bits (388), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 75/201 (37%), Positives = 128/201 (63%), Gaps = 1/201 (0%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F+ L+ +LL GI+ G+EKPS IQ+ +I + GRD++A++++GTGK+ + I +L+ Sbjct: 5 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 64 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQH 158 LD++ QA+++ PTRELA+Q+ + + + +M + A GGTN+ +DI +LD H Sbjct: 65 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 124 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 VV TPGR+ D+I++ + ++M+VLDEAD++L++ F + + D+ LP Q++L S Sbjct: 125 VVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYS 184 Query: 219 ATLPHEILEMTNKFMTDPIRI 239 AT P + + N + P I Sbjct: 185 ATFPLSVQKFMNSHLEKPYEI 205 >2OXC-A nrPDB Length = 230 Score = 152 bits (384), Expect = 3e-37, Method: Compositional matrix adjust. Identities = 86/219 (39%), Positives = 131/219 (59%), Gaps = 4/219 (1%) Query: 21 EDMTKVEFETSEEVDVTPT-FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVI 79 +D++ T + + P F+++ L +L G+ A GFE+PS +Q +AI G D+I Sbjct: 6 QDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDLI 65 Query: 80 AQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCH 138 Q++SGTGKT FS L L ++ TQ LILAPTRE+AVQI + A+G M ++CH Sbjct: 66 VQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLECH 125 Query: 139 ACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG-F 197 IGGT + +D +L H+ G+PGR+ +I L +I++ +LDEAD++L +G F Sbjct: 126 VFIGGTPLSQDKTRLKKC-HIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGSF 184 Query: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDP 236 +EQI +Y LP + Q++ +SAT P + K+M DP Sbjct: 185 QEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDP 223 >3I62-A nrPDB Length = 563 Score = 150 bits (380), Expect = 8e-37, Method: Compositional matrix adjust. Identities = 115/403 (28%), Positives = 203/403 (50%), Gaps = 45/403 (11%) Query: 29 ETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGT 86 + S+EV + + L +++ + I F + +QQ+ IK I+ DVIA++++GT Sbjct: 63 DNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGT 122 Query: 87 GKTATFSISVLQCLDIQVRETQ----ALILAPTRELAVQIQKGLLALGDYMNV-----QC 137 GKT F I + Q L ++Q A+I+APTR+LA+QI+ + + D MN C Sbjct: 123 GKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHD-MNYGLKKYAC 181 Query: 138 HACIGGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRT-RAIKMLVLDEADEMLNK 195 + +GGT+ + K++ ++V TPGR+ D++ + S + R + VLDEAD +L Sbjct: 182 VSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEI 241 Query: 196 GFKEQIYDVYRYLPPAT-------QVVLISATLPHEILEMTNKFMTDPIRILV----KRD 244 GF++ + + L + +L SATL ++ ++ N M + + K + Sbjct: 242 GFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNE 301 Query: 245 ELTLEGIKQ-----------FFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWL 293 E I Q F AVE + + Y +A+IF T + +L Sbjct: 302 PEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNY------KAIIFAPTVKFTSFL 355 Query: 294 TEKMR---EANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350 ++ + + + HG + Q +R S++K F+ S +L+ TDV ARG+D P V ++ Sbjct: 356 CSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVL 415 Query: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIE 393 +P+ YIHRIGR+ R G++G ++ F+ D++ +R++E Sbjct: 416 QIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELE 458 >3SQW-A nrPDB Length = 579 Score = 149 bits (377), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 116/403 (28%), Positives = 206/403 (51%), Gaps = 45/403 (11%) Query: 29 ETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGT 86 + S+EV + + L +++ + I F + +QQ+ IK I+ DVIA++++GT Sbjct: 12 DNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARAKTGT 71 Query: 87 GKTATFSISVLQCLDIQVRETQ----ALILAPTRELAVQIQKGLLALGDYMN--VQCHAC 140 GKT F I + Q L ++Q A+I+APTR+LA+QI+ + + D MN ++ +AC Sbjct: 72 GKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHD-MNYGLKKYAC 130 Query: 141 I---GGTNVGEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRT-RAIKMLVLDEADEMLNK 195 + GGT+ + K++ ++V TPGR+ D++ + S + R + VLDEAD +L Sbjct: 131 VSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRLLEI 190 Query: 196 GFKEQIYDVYRYLPPAT-------QVVLISATLPHEILEMTNKFMTDPIRILV----KRD 244 GF++ + + L + +L SATL ++ ++ N M + + K + Sbjct: 191 GFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVDKNE 250 Query: 245 ELTLEGIKQ-----------FFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWL 293 E I Q F AVE + + Y +A+IF T + +L Sbjct: 251 PEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNY------KAIIFAPTVKFTSFL 304 Query: 294 TEKMR---EANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350 ++ + + + HG + Q +R S++K F+ S +L+ TDV ARG+D P V ++ Sbjct: 305 CSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVHEVL 364 Query: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIE 393 +P+ YIHRIGR+ R G++G ++ F+ D++ +R++E Sbjct: 365 QIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELE 407 >6AIC-A nrPDB Length = 214 Score = 144 bits (364), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 74/198 (37%), Positives = 119/198 (60%), Gaps = 2/198 (1%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F +G+ ++ ++ + + GF++P+ IQ+ +I ++G D++ Q+Q+GTGKT F I +++ Sbjct: 4 FKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIEK 63 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159 + + + Q+LILAPTRELA+Q+ + L VQ GG + I+ L G + Sbjct: 64 V-VGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALKKGPQI 122 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT-QVVLIS 218 V GTPGRV D + RR+L+T I L+LDEADEM+N GF + + + +P Q +L S Sbjct: 123 VVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQTMLFS 182 Query: 219 ATLPHEILEMTNKFMTDP 236 AT+P I + +FM P Sbjct: 183 ATMPKAIQALVQQFMKSP 200 >1T6N-A nrPDB Length = 220 Score = 144 bits (363), Expect = 7e-35, Method: Compositional matrix adjust. Identities = 80/200 (40%), Positives = 113/200 (56%), Gaps = 3/200 (1%) Query: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104 L+ +LLR I GFE PS +Q I Q I G DV+ Q++SG GKTA F ++ LQ L+ Sbjct: 21 LKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQLEPVT 80 Query: 105 RETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYG-QHVVAG 162 + L++ TRELA QI K YM NV+ GG ++ +D L H+V G Sbjct: 81 GQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCPHIVVG 140 Query: 163 TPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVLISATL 221 TPGR+ + R +SL + IK +LDE D+ML + + + +++R P QV++ SATL Sbjct: 141 TPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMMFSATL 200 Query: 222 PHEILEMTNKFMTDPIRILV 241 EI + KFM DP+ I V Sbjct: 201 SKEIRPVCRKFMQDPMEIFV 220 >2KBE-A nrPDB Length = 226 Score = 142 bits (357), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 79/200 (39%), Positives = 126/200 (63%), Gaps = 7/200 (3%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISV 96 +FD +GL +LL+GIYA F+KPS IQ+RA+ ++ R++IAQSQSGTGKTA FS+++ Sbjct: 23 SFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSLTM 82 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYG 156 L ++ + QA+ LAP+RELA Q + + +G + + + + E ++++ Sbjct: 83 LTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIVPDS--FEKNKQINA- 139 Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQVV 215 V+ GTPG V D++RR+ ++ + IK+ VLDEAD ML+ +G +Q V R+LP TQ+V Sbjct: 140 -QVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQLV 198 Query: 216 LISATLPHEILEMTNKFMTD 235 L SAT + + K + + Sbjct: 199 LFSATFADAVRQYAKKIVPN 218 >2GXQ-A nrPDB Length = 207 Score = 135 bits (340), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 72/203 (35%), Positives = 117/203 (57%), Gaps = 5/203 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ ++L ++ G P+ IQ A+ ++G+D+I Q+++GTGKT F++ + + Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 100 LDI---QVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYG 156 L + R+ +AL+L PTRELA+Q+ L A+ ++ V A GGT G+ L G Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASELTAVAPHLKVV--AVYGGTGYGKQKEALLRG 120 Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVL 216 V TPGR D +R+ L +++ VLDEADEML+ GF+E++ + PP+ Q +L Sbjct: 121 ADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLL 180 Query: 217 ISATLPHEILEMTNKFMTDPIRI 239 SATLP + ++M +P+ I Sbjct: 181 FSATLPSWAKRLAERYMKNPVLI 203 >1Q0U-A nrPDB Length = 219 Score = 127 bits (319), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 68/201 (33%), Positives = 111/201 (55%), Gaps = 4/201 (1%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F + ++ I F KP+ IQ+R I ++G ++ QSQ+GTGKT + + +++ Sbjct: 6 FTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLPIMEK 65 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMN----VQCHACIGGTNVGEDIRKLDY 155 + + E QA+I APTRELA QI L + + + IGGT+ + + KL+ Sbjct: 66 IKPERAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQKALEKLNV 125 Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 215 H+V GTPGR+ D IR ++L +LV+DEAD ML+ GF + + +P Q++ Sbjct: 126 QPHIVIGTPGRINDFIREQALDVHTAHILVVDEADLMLDMGFITDVDQIAARMPKDLQML 185 Query: 216 LISATLPHEILEMTNKFMTDP 236 + SAT+P ++ K+M +P Sbjct: 186 VFSATIPEKLKPFLKKYMENP 206 >1WRB-A nrPDB Length = 253 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 79/234 (33%), Positives = 124/234 (52%), Gaps = 17/234 (7%) Query: 35 DVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSI 94 +V FD + L + I +++P+ IQ+ AI I++ RD++A +Q+G+GKTA F I Sbjct: 20 NVIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILEHRDIMACAQTGSGKTAAFLI 79 Query: 95 SVLQ---CLDIQVRE------TQALILAPTRELAVQIQKGLLALGDYMNVQCHACI--GG 143 ++ C D+ + + LILAPTRELA+QI +N +C+ GG Sbjct: 80 PIINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSESQKFS--LNTPLRSCVVYGG 137 Query: 144 TNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYD 203 + IR++ G H++ TPGR+ D I + + K +VLDEAD ML+ GF+ QI Sbjct: 138 ADTHSQIREVQMGCHLLVATPGRLVDFIEKNKISLEFCKYIVLDEADRMLDMGFEPQIRK 197 Query: 204 VYR--YLPPAT--QVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQ 253 + +P Q ++ SAT P EI ++ F+ + I + V R T + IKQ Sbjct: 198 IIEESNMPSGINRQTLMFSATFPKEIQKLAADFLYNYIFMTVGRVGSTSDSIKQ 251 >3BER-A nrPDB Length = 249 Score = 125 bits (313), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 68/210 (32%), Positives = 114/210 (54%), Gaps = 1/210 (0%) Query: 33 EVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATF 92 E + T TF +G+ + L G+ KP+ IQ AI ++GRD+I +++G+GKT F Sbjct: 38 EEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQGRDIIGLAETGSGKTGAF 97 Query: 93 SISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRK 152 ++ +L L + AL+L PTRELA QI + ALG + VQ +GG + Sbjct: 98 ALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGVQSAVIVGGIDSMSQSLA 157 Query: 153 LDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPA 211 L H++ TPGR+ D + + RA+K LV+DEAD +LN F+ ++ + + +P Sbjct: 158 LAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILNMDFETEVDKILKVIPRD 217 Query: 212 TQVVLISATLPHEILEMTNKFMTDPIRILV 241 + L SAT+ ++ ++ + +P++ V Sbjct: 218 RKTFLFSATMTKKVQKLQRAALKNPVKCAV 247 >3FHC-B nrPDB Length = 235 Score = 123 bits (308), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 78/216 (36%), Positives = 124/216 (57%), Gaps = 16/216 (7%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII--KGRDVIAQSQSGTGKTATFSISV 96 +F+ + L+ LL+G+YA GF +PS IQ+ A+ ++ +++IAQSQSGTGKTA F +++ Sbjct: 26 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 85 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDY 155 L ++ + Q L L+PT ELA+Q K + +G Y ++ + G KL+ Sbjct: 86 LSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLER 138 Query: 156 GQ----HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLP 209 GQ +V GTPG V D + + + + IK+ VLDEAD M+ +G ++Q + R LP Sbjct: 139 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 198 Query: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 Q++L SAT + + K + DP I +KR+E Sbjct: 199 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREE 234 >3FMO-B nrPDB Length = 300 Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 77/215 (35%), Positives = 123/215 (57%), Gaps = 16/215 (7%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII--KGRDVIAQSQSGTGKTATFSISV 96 +F+ + L+ LL+G+YA GF +PS IQ+ A+ ++ +++IAQSQSGTGKTA F +++ Sbjct: 93 SFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVLAM 152 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKLDY 155 L ++ + Q L L+PT ELA+Q K + +G Y ++ + G KL+ Sbjct: 153 LSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGN-------KLER 205 Query: 156 GQ----HVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLP 209 GQ +V GTPG V D + + + + IK+ VLDEAD M+ +G ++Q + R LP Sbjct: 206 GQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLP 265 Query: 210 PATQVVLISATLPHEILEMTNKFMTDPIRILVKRD 244 Q++L SAT + + K + DP I +KR+ Sbjct: 266 RNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKRE 300 >5H1Y-A nrPDB Length = 281 Score = 119 bits (299), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 70/219 (31%), Positives = 113/219 (51%), Gaps = 14/219 (6%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 +F M +LRG+ G P+ IQ + I I+ GRD+I + +G+GKT F++ V+ Sbjct: 53 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 112 Query: 99 -CLDIQVR-------ETQALILAPTRELAVQIQK------GLLALGDYMNVQCHACIGGT 144 CL+ + R LI+ P+RELA Q LL ++C CIGG Sbjct: 113 FCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 172 Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204 +V E + + +G H++ TPGR+ D+++++ + + L LDEAD M++ GF+ I + Sbjct: 173 SVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTI 232 Query: 205 YRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR 243 + Y Q +L SAT+P +I + P+ I V R Sbjct: 233 FSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGR 271 >5GVS-A nrPDB Length = 231 Score = 117 bits (294), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 69/217 (31%), Positives = 112/217 (51%), Gaps = 14/217 (6%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 +F M +LRG+ G P+ IQ + I I+ GRD+I + +G+GKT F++ V+ Sbjct: 14 SFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSGKTLVFTLPVIM 73 Query: 99 -CLDIQVR-------ETQALILAPTRELAVQIQK------GLLALGDYMNVQCHACIGGT 144 CL+ + R LI+ P+RELA Q LL ++C CIGG Sbjct: 74 FCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSPLLRCALCIGGM 133 Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204 +V E + + +G H++ TPGR+ D+++++ + + L LDEAD M++ GF+ I + Sbjct: 134 SVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMIDMGFEGDIRTI 193 Query: 205 YRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILV 241 + Y Q +L SAT+P +I + P+ I V Sbjct: 194 FSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINV 230 >4PX9-A nrPDB Length = 292 Score = 111 bits (278), Expect = 6e-25, Method: Compositional matrix adjust. Identities = 80/252 (31%), Positives = 125/252 (49%), Gaps = 32/252 (12%) Query: 24 TKVEFETSEEVDVTPT----------FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII 73 T + FE +++ V T F + + E ++ I + +P+ +Q+ AI I Sbjct: 41 TGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIK 100 Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCL---------------DIQVRETQ---ALILAPT 115 + RD++A +Q+G+GKTA F + +L + R Q +L+LAPT Sbjct: 101 EKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPT 160 Query: 116 RELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRS 175 RELAVQI + V+ GG ++G+ IR L+ G H++ TPGR+ DM+ R Sbjct: 161 RELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGK 220 Query: 176 LRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPP--ATQVVLISATLPHEILEMTNK 231 + K LVLDEAD ML+ GF+ QI + +PP ++ SAT P EI + Sbjct: 221 IGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARD 280 Query: 232 FMTDPIRILVKR 243 F+ + I + V R Sbjct: 281 FLDEYIFLAVGR 292 >3IUY-A nrPDB Length = 228 Score = 106 bits (265), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 68/200 (34%), Positives = 107/200 (53%), Gaps = 7/200 (3%) Query: 48 DLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV--R 105 DLL+ I G KP+ IQ +A I++G D+I +Q+GTGKT ++ + LD Q R Sbjct: 30 DLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSYLMPGFIHLDSQPISR 89 Query: 106 ETQ----ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161 E + L+L PTRELA+ ++ Y ++ GG N I + G ++ Sbjct: 90 EQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNRNGQIEDISKGVDIII 148 Query: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATL 221 TPGR+ D+ S+ R+I LV+DEAD+ML+ F+ QI + + P Q V+ SAT Sbjct: 149 ATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILLDVRPDRQTVMTSATW 208 Query: 222 PHEILEMTNKFMTDPIRILV 241 P + ++ ++ DP+ + V Sbjct: 209 PDTVRQLALSYLKDPMIVYV 228 >3LY5-A nrPDB Length = 262 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 62/185 (33%), Positives = 107/185 (57%), Gaps = 13/185 (7%) Query: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104 + E+ L+ I GF + IQ ++I+ +++GRD++A +++G+GKT F I ++ + +++ Sbjct: 61 VNENTLKAIKEMGFTNMTEIQHKSIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELI-VKL 119 Query: 105 R-----ETQALILAPTRELAVQIQKGLLALGDYMNVQCHA---CIGGTNVGEDIRKLDYG 156 R T LIL+PTRELA+Q L + M H +GG+N + +KL G Sbjct: 120 RFMPRNGTGVLILSPTRELAMQT---FGVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNG 176 Query: 157 QHVVAGTPGRVFD-MIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 215 +++ TPGR+ D M + ++ LV+DEAD +L+ GF+E++ + + LP Q + Sbjct: 177 INIIVATPGRLLDHMQNTPGFMYKNLQCLVIDEADRILDVGFEEELKQIIKLLPTRRQTM 236 Query: 216 LISAT 220 L SAT Sbjct: 237 LFSAT 241 >3FE2-A nrPDB Length = 242 Score = 104 bits (259), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 67/201 (33%), Positives = 102/201 (50%), Gaps = 19/201 (9%) Query: 58 FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQ-----ALIL 112 F +P+AIQ + + G D++ +Q+G+GKT ++ + + ++ Q + L+L Sbjct: 49 FTEPTAIQAQGWPVALSGLDMVGVAQTGSGKTLSYLLPAIVHINHQPFLERGDGPICLVL 108 Query: 113 APTRELAVQIQKGLLALGDYMNVQCHAC-------IGGTNVGEDIRKLDYGQHVVAGTPG 165 APTRELA Q+Q+ +Y C AC GG G IR L+ G + TPG Sbjct: 109 APTRELAQQVQQ---VAAEY----CRACRLKSTCIYGGAPKGPQIRDLERGVEICIATPG 161 Query: 166 RVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEI 225 R+ D + R LVLDEAD ML+ GF+ QI + + P Q ++ SAT P E+ Sbjct: 162 RLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLMWSATWPKEV 221 Query: 226 LEMTNKFMTDPIRILVKRDEL 246 ++ F+ D I I + EL Sbjct: 222 RQLAEDFLKDYIHINIGALEL 242 >2PL3-A nrPDB Length = 236 Score = 90.5 bits (223), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 60/202 (29%), Positives = 105/202 (51%), Gaps = 6/202 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L + L+G+ + + IQ++ I ++G+DV+ +++G+GKT F + VL+ Sbjct: 27 FSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFLVPVLEA 86 Query: 100 L-DIQVRETQAL---ILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDY 155 L +Q T L I++PTRELA Q + L +G + IGG ++ + +++ Sbjct: 87 LYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHEAERIN- 145 Query: 156 GQHVVAGTPGRVFD-MIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQV 214 +++ TPGR+ M S ++MLVLDEAD +L+ GF + + V LP Q Sbjct: 146 NINILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENLPKKRQT 205 Query: 215 VLISATLPHEILEMTNKFMTDP 236 +L SAT + ++ + +P Sbjct: 206 LLFSATQTKSVKDLARLSLKNP 227 >3DKP-A nrPDB Length = 245 Score = 82.4 bits (202), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 54/196 (27%), Positives = 105/196 (53%), Gaps = 19/196 (9%) Query: 25 KVEFETSEEVDVTPTFDTM----GLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIA 80 K+ + ++ D TF + + LL+ I GF+ P+ IQ +AI ++ GR+++A Sbjct: 12 KIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 71 Query: 81 QSQSGTGKTATFSISVLQCLDIQVRET-QALILAPTRELAVQIQKGLLALGDYMNVQCH- 138 + +G+GKT FSI +L L + +ALI++PTRELA QI + L+ + + + H Sbjct: 72 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 131 Query: 139 ---ACIGGTNVG-EDIRKLDYGQHVVAGTPGRVFDMIRR--RSLRTRAIKMLVLDEADEM 192 A + G + +K D ++ TP R+ ++++ + +++ LV+DE+D++ Sbjct: 132 IHKAAVAAKKFGPKSSKKFD----ILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKL 187 Query: 193 L---NKGFKEQIYDVY 205 GF++Q+ ++ Sbjct: 188 FEDGKTGFRDQLASIF 203 >6CRM-A nrPDB Length = 541 Score = 67.8 bits (164), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 77/355 (21%), Positives = 151/355 (42%), Gaps = 46/355 (12%) Query: 56 YGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115 +G+++ Q I +++GRD + +G GK+ + I L V+ ++++P Sbjct: 41 FGYQQFRPGQATIIDAVLEGRDCLVVMPTGGGKSLCYQIPAL------VKTGLTIVVSPL 94 Query: 116 RELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAG-----------TP 164 L LLA N AC+ T E+ Q V+AG P Sbjct: 95 ISLMKDQVDQLLA-----NGVAAACLNSTQSREE------QQAVLAGCRTGQVRLLYIAP 143 Query: 165 GRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQIYDV--YRYLPPATQVVLISAT 220 R+ +L + M+ +DEA + G F+ + + R PA + ++AT Sbjct: 144 ERLMMDNFIDTLGYWDLAMVAVDEAHCISQWGHDFRPEYAALGQLRARFPAVPFMALTAT 203 Query: 221 LP----HEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWK-FDTLCDLYDTL 275 +I+ + + DP L++ I+ + E++K D L Sbjct: 204 ADDTTRRDIVRLLG--LDDP---LIEISSFDRPNIRYMLM----EKFKPLDQLMRYVQEQ 254 Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335 +I+CN++ KV+ +++ + ++ H + + R S+ ++F+ +++++T Sbjct: 255 RGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLEHEVRASVQEKFQRDDLQIVVATV 314 Query: 336 VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILR 390 + G++ P V ++++D+P N E Y GR+GR G A+ F D+ LR Sbjct: 315 AFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLR 369 >1OYY-A nrPDB Length = 523 Score = 64.3 bits (155), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 27/111 (24%), Positives = 59/111 (53%) Query: 280 AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 +I+CN++ KV+ +++ + ++ H + R + ++F+ +++++T + Sbjct: 239 GIIYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGM 298 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILR 390 G++ P V ++++D+P N E Y GR+GR G A+ F D+ LR Sbjct: 299 GINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLR 349 >5LST-A nrPDB Length = 693 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 34/126 (26%), Positives = 59/126 (46%), Gaps = 16/126 (12%) Query: 281 VIFCNTKRKVD-------------WLT-EKMREANFTVSSMHGDMPQKERESIMKEFRSG 326 +I+CN + + W+ R T + H M +ER + + F G Sbjct: 281 IIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQRAFMQG 340 Query: 327 ASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV--KND 384 RV+++T + GLD P V +++ LP + E Y+ +GR+GR G+ F+ + + Sbjct: 341 QLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFLQPQGE 400 Query: 385 DIRILR 390 D+R LR Sbjct: 401 DLRELR 406 >4CDG-A nrPDB Length = 673 Score = 55.1 bits (131), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 75/361 (20%), Positives = 147/361 (40%), Gaps = 47/361 (13%) Query: 56 YGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115 +G Q AI + G D +G GK+ + + C+ V ++++P Sbjct: 30 FGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPA--CVSPGV----TVVISPL 83 Query: 116 RELAV-QIQKGLLAL--------GDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGR 166 R L V Q+QK L +L GD + + TN+ + K D ++ TP + Sbjct: 84 RSLIVDQVQK-LTSLDIPATYLTGDKTDSE------ATNIYLQLSKKDPIIKLLYVTPEK 136 Query: 167 V---------FDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQI--YDVYRYLPPATQ 213 + + + R L R V+DEA + G F++ ++ R P+ Sbjct: 137 ICASNRLISTLENLYERKLLAR----FVIDEAHCVSQWGHDFRQDYKRMNMLRQKFPSVP 192 Query: 214 VVLISATLPHEILEMTNKFMTDPIRIL---VKRDELTLEGIKQFFVAVEREEWKFDTLCD 270 V+ ++AT + K + ++IL V +K + + + ++ FD L Sbjct: 193 VMALTATANPRV----QKDILTQLKILRPQVFSMSFNRHNLKYYVLPKKPKKVAFDCLEW 248 Query: 271 LYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEF-RSGASR 329 + +I+C ++R+ D + + ++ + H + R+ + +++ + Sbjct: 249 IRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSARDEVQQKWINQDGCQ 308 Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRIL 389 V+ +T + G+D P V +I+ LP + E Y GR+GR G + F D+ L Sbjct: 309 VICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEISHCLLFYTYHDVTRL 368 Query: 390 R 390 + Sbjct: 369 K 369 >1D9Z-A nrPDB Length = 657 Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 7/91 (7%) Query: 286 TKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQ 345 TK+ + LT+ ++EA V+ +H ++ ER I+++ R G VL+ ++ GLD+P+ Sbjct: 453 TKKMAEDLTDYLKEAGIKVAYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPE 512 Query: 346 VSLIINYD------LPNNRELYIHRIGRSGR 370 VSL+ D L + R L I IGR+ R Sbjct: 513 VSLVAILDADKEGFLRSERSL-IQTIGRAAR 542 >4Q48-A nrPDB Length = 525 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 22/98 (22%), Positives = 47/98 (47%) Query: 280 AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 +++C +++ V+ + ++ + H + ER ++ + F + ++ +T + Sbjct: 239 GIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVAFGM 298 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377 G+D P V + + DLP + E Y GR+GR G A Sbjct: 299 GIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTA 336 >1WP9-A nrPDB Length = 494 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 33/96 (34%), Positives = 50/96 (52%), Gaps = 5/96 (5%) Query: 311 MPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR 370 + Q+E++ I+ EF G VL++T V GLDVP+V L++ Y+ + I R GR+GR Sbjct: 403 LSQREQKLILDEFARGEFNVLVATSVGEEGLDVPEVDLVVFYEPVPSAIRSIQRRGRTGR 462 Query: 371 YGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMN 406 + V I K RD Y+S++ E M Sbjct: 463 HMPGRVIILMAKGT-----RDEAYYWSSRQKEKIMQ 493 >5AGA-A nrPDB Length = 830 Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 90/435 (20%), Positives = 183/435 (42%), Gaps = 102/435 (23%) Query: 44 GLREDLLRGIYAYGFEKPSAIQQRAI--KQIIKGRDVIAQSQSGTGKTATFSISVLQCLD 101 GL + +L +++G +K Q + Q+++G++++ + + GKT + +L+ + Sbjct: 11 GLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKRV- 69 Query: 102 IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161 +++R+ +AL + P +A + + L +L + ++ +G T+ LD + Sbjct: 70 LEMRK-KALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIE 128 Query: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEML---NKGFKEQIY---------------- 202 G + +I + + M+V+DE ML ++G+ ++ Sbjct: 129 RANGLINRLIEENKMDL--LGMVVVDEL-HMLGDSHRGYLLELLLTKICYITRKSASCQA 185 Query: 203 DVYRYLPPATQVVLISATLPHEILEMTNKFM------TD--PIRIL--VKRD----ELTL 248 D+ L A Q+V +SATLP+ LE+ ++ TD P+ +L VK + ++ Sbjct: 186 DLASSLSNAVQIVGMSATLPN--LELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSM 243 Query: 249 EGIKQF--FVAVEREEWKFDTLCDLYDTLTITQAV-IFCNTKRKVDWLTEKM-------- 297 + +++F + V+ +E +LC Y+T+ +V +FC +K+ + L + + Sbjct: 244 KLVREFEPMLQVKGDEDHVVSLC--YETICDNHSVLLFCPSKKWCEKLADIIAREFYNLH 301 Query: 298 -----------------------------------------REANFTVSSMHGDMPQKER 316 + + V+ H + +ER Sbjct: 302 HQAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEER 361 Query: 317 ESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL----YIHRIGRSGRYG 372 + I FR G RVL +T + G+++P +II + R L Y +GR+GR G Sbjct: 362 DIIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKG 421 Query: 373 --RKGVAINFVKNDD 385 G +I KN + Sbjct: 422 VDTVGESILICKNSE 436 >1GM5-A nrPDB Length = 780 Score = 48.5 bits (114), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 66/310 (21%), Positives = 137/310 (44%), Gaps = 27/310 (8%) Query: 79 IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCH 138 + Q G+GKT +++L + Q + PT LA+Q + + N+ Sbjct: 393 LLQGDVGSGKTVVAQLAILDNYEAGF---QTAFMVPTSILAIQHYRRTVESFSKFNIHVA 449 Query: 139 ACIGGTNVGEDIR---KLDYGQ-HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEA----- 189 IG T E + L GQ VV GT + + + + + ++++DE Sbjct: 450 LLIGATTPSEKEKIKSGLRNGQIDVVIGTHALI-----QEDVHFKNLGLVIIDEQHRFGV 504 Query: 190 ---DEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDEL 246 + ++NKG ++ D + AT + A + L++T P R V+ + Sbjct: 505 KQREALMNKG---KMVDTL--VMSATPIPRSMALAFYGDLDVTVIDEMPPGRKEVQTMLV 559 Query: 247 TLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSS 306 ++ + + + V +E + +Y + + + + ++L++++ F + Sbjct: 560 PMDRVNEVYEFVRQEVMRGGQAFIVYPLIEESDKLNVKSAVEMYEYLSKEVF-PEFKLGL 618 Query: 307 MHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI- 365 MHG + Q+E++ +M EF G +L+ST V G+DVP+ ++++ + +H++ Sbjct: 619 MHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRANVMVIENPERFGLAQLHQLR 678 Query: 366 GRSGRYGRKG 375 GR GR G++ Sbjct: 679 GRVGRGGQEA 688 >2WWY-A nrPDB Length = 591 Score = 48.1 bits (113), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 21/107 (19%), Positives = 55/107 (51%) Query: 280 AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 +I+C +++ + +T ++ + H ++ +++ ++ +++ + +V+++T + Sbjct: 270 GIIYCFSQKDSEQVTVSLQNLGIHAGAYHANLEPEDKTTVHRKWSANEIQVVVATVAFGM 329 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDI 386 G+D P V +I++ + + E Y GR+GR K I + DI Sbjct: 330 GIDKPDVRFVIHHSMSKSMENYYQESGRAGRDDMKADCILYYGFGDI 376 >2NMV-A nrPDB Length = 661 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 30/91 (32%), Positives = 50/91 (54%), Gaps = 7/91 (7%) Query: 286 TKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQ 345 TK+ + LT+ ++E V+ +H ++ ER I+++ R G VL+ ++ GLD+P+ Sbjct: 454 TKKMSEDLTDYLKEIGIKVNYLHSEIKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPE 513 Query: 346 VSLIINYD------LPNNRELYIHRIGRSGR 370 VSL+ D L + R L I IGR+ R Sbjct: 514 VSLVAILDADKEGFLRSERSL-IQTIGRAAR 543 >5V9X-A nrPDB Length = 877 Score = 47.8 bits (112), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 77/400 (19%), Positives = 154/400 (38%), Gaps = 81/400 (20%) Query: 41 DTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL 100 D +G L R + F P+ Q A I +G + + + +G+GKT + + L Sbjct: 28 DPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRL 87 Query: 101 DIQVRE----TQALILAPTRELAVQIQK-------GLLALGDYMNVQCHACIGGTNVGED 149 RE TQ L ++P + LAV +++ G+ + + + + G G+ Sbjct: 88 ADPAREPSQGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDT 147 Query: 150 IRK-----LDYGQHVVAGTPGRVFDMIRRRSLRT-RAIKMLVLDE----------ADEML 193 + V+ TP +F M+ + T +++ +++DE A L Sbjct: 148 PPNQRRAMIANPPDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLAL 207 Query: 194 NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTD--PIRILVKRDELTLEGI 251 + +Q+ D PA ++ L + P E + +F++ P I+ T + Sbjct: 208 SLERLDQLLDT-----PAQRIGLSATVRPPEEVA---RFLSGQAPTTIVCPPAAKTFDLS 259 Query: 252 KQFFVAV-----EREEWK--FDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTV 304 Q V W + + DL + +++F N++R + LT ++ E + Sbjct: 260 VQVPVPDMANLDNNSIWPDVEERIVDLVEAHN--SSIVFANSRRLAERLTSRLNEIHAER 317 Query: 305 SSM-----------------------------------HGDMPQKERESIMKEFRSGASR 329 S + HG + +++R + + +SG R Sbjct: 318 SGIELPAGPNPEVGGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLR 377 Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSG 369 +++T G+D+ V L+I + P + + R+GR+G Sbjct: 378 AVVATSSLELGIDMGAVDLVIQVEAPPSVASGLQRVGRAG 417 >4GL2-A nrPDB Length = 699 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 36/145 (24%), Positives = 63/145 (43%), Gaps = 22/145 (15%) Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLT--------ITQAVIFCNTKRKV----DWL 293 L E K E E++ + L L +T+ + +IF T++ W+ Sbjct: 361 LFFENNKMLKRLAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWI 420 Query: 294 TEKMREANFTVSSMH----------GDMPQKERESIMKEFRSGASRVLISTDVWARGLDV 343 TE + A V + H M Q E++ ++ +FR+G +LI+T V GLD+ Sbjct: 421 TENEKFAEVGVKAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDI 480 Query: 344 PQVSLIINYDLPNNRELYIHRIGRS 368 + +++I Y L N + GR+ Sbjct: 481 KECNIVIRYGLVTNEIAMVQARGRA 505 >5JCF-A nrPDB Length = 701 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 38/160 (23%), Positives = 74/160 (46%), Gaps = 22/160 (13%) Query: 266 DTLCDLYDTLTITQAVIFCNTKRKV----DWLTEKMR------EANFTVSSMHGD----M 311 +TL + + + +IF T++ W+ + + +A+F + + H M Sbjct: 388 NTLMEEFTKTEEPRGIIFTKTRQSALALYHWIMDNPKFEEVGIKAHFLIGAGHNSETKPM 447 Query: 312 PQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRY 371 Q E+ ++ +FR G+ +LI+T V GLD+ + +++I Y L N + GR+ R Sbjct: 448 TQNEQREVIDKFRGGSINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA-RA 506 Query: 372 GRKGVAI------NFVKNDDIRILRDIEQYYST-QIDEMP 404 A+ V+ +D+ I R+ Y + ++ EMP Sbjct: 507 DESTYALVASSGSGAVEREDVNIFRENMMYKAIRRVQEMP 546 >6G19-A nrPDB Length = 696 Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 27/105 (25%), Positives = 50/105 (47%), Gaps = 14/105 (13%) Query: 278 TQAVIFCNTKRKV----DWLTEKMREANFTVSSMH----------GDMPQKERESIMKEF 323 ++ +IF T++ W+ E + A V + H M Q E++ ++ +F Sbjct: 395 SRGIIFTKTRQSTYALSQWIMENAKFAEVGVKAHHLIGAGHSSEVKPMTQTEQKEVISKF 454 Query: 324 RSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRS 368 R+G +LI+T V GLD+ + +++I Y L N + GR+ Sbjct: 455 RTGEINLLIATTVAEEGLDIKECNIVIRYGLVTNEIAMVQARGRA 499 >5TNU-A nrPDB Length = 459 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 19/53 (35%), Positives = 33/53 (62%) Query: 315 ERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGR 367 ERE I+++FR G RV++++ V+ G+DVP +L I + ++ R+GR Sbjct: 377 EREEILQKFRDGEYRVIVASTVFDEGVDVPDATLAIVMGGYGTKRQFLQRLGR 429 >5JBJ-A nrPDB Length = 680 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 16/106 (15%) Query: 278 TQAVIFCNTKRK----VDWLT-------EKMREANFTVSSMHGD----MPQKERESIMKE 322 ++ ++F T++ + WL + +R A T S H + M Q E++ ++ Sbjct: 372 SRGIVFTKTRQSAHSLLSWLQDTAGLCGQHIRAAVLT-GSGHSNQAKGMTQNEQQDVITL 430 Query: 323 FRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRS 368 FR G +L ST V GLD+P+ ++++ Y L N + GR+ Sbjct: 431 FRYGELNLLFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRA 476 >2FWR-A nrPDB Length = 472 Score = 41.6 bits (96), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 37/66 (56%) Query: 302 FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELY 361 F + ++ ++ERE I++ FR+G R ++S+ V G+DVP ++ + + Y Sbjct: 369 FLIPAITHRTSREEREEILEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREY 428 Query: 362 IHRIGR 367 I R+GR Sbjct: 429 IQRLGR 434 >1C4O-A nrPDB Length = 664 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/97 (28%), Positives = 48/97 (49%), Gaps = 7/97 (7%) Query: 286 TKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQ 345 T R + LT + E +H ++ +R++++++ R G L+ ++ GLD+P+ Sbjct: 448 TVRMAEELTSFLVEHGIRARYLHHELDAFKRQALIRDLRLGHYDCLVGINLLREGLDIPE 507 Query: 346 VSLIINYD------LPNNRELYIHRIGRSGRYGRKGV 376 VSL+ D L + R L I IGR+ R R V Sbjct: 508 VSLVAILDADKEGFLRSERSL-IQTIGRAARNARGEV 543 >5LBA-B nrPDB Length = 445 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 19/106 (17%), Positives = 47/106 (44%), Gaps = 1/106 (0%) Query: 280 AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 +++C T+ + L ++ + H + ER + ++ V+++T + Sbjct: 254 GIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGM 313 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA-INFVKND 384 G+D V + ++++ + Y GR+GR G+ + + +ND Sbjct: 314 GVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 359 >5LB8-A nrPDB Length = 518 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 19/106 (17%), Positives = 47/106 (44%), Gaps = 1/106 (0%) Query: 280 AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 +++C T+ + L ++ + H + ER + ++ V+++T + Sbjct: 254 GIVYCRTREACEQLAIELSCRGVNAKAYHAGLKASERTLVQNDWMEEKVPVIVATISFGM 313 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA-INFVKND 384 G+D V + ++++ + Y GR+GR G+ + + +ND Sbjct: 314 GVDKANVRFVAHWNIAKSMAGYYQESGRAGRDGKPSWCRLYYSRND 359 >6BOG-A nrPDB Length = 968 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 38/138 (27%), Positives = 58/138 (42%), Gaps = 7/138 (5%) Query: 243 RDELTLEGIKQFFVAVEREEWKFDTLCDL---YDTLTITQAV-IFCNTKRKVDWLTEKMR 298 RD L E I Q F W FD + Y T +Q V + C L + +R Sbjct: 465 RDMLYPERIYQEFEGDNATWWNFDPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLR 524 Query: 299 E-ANFTVSSMHGDMPQKERESIMKEF--RSGASRVLISTDVWARGLDVPQVSLIINYDLP 355 E + H M ER+ F ++VL+ +++ + G + S ++ +DLP Sbjct: 525 EREGIRAAVFHEGMSIIERDRAAAWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLP 584 Query: 356 NNRELYIHRIGRSGRYGR 373 N +L RIGR R G+ Sbjct: 585 FNPDLLEQRIGRLDRIGQ 602 >2P6R-A nrPDB Length = 702 Score = 35.8 bits (81), Expect = 0.031, Method: Compositional matrix adjust. Identities = 85/395 (21%), Positives = 161/395 (40%), Gaps = 75/395 (18%) Query: 54 YAYGFEKPSAI------QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRET 107 YA G K I Q A++++ G++++ + GKT +++++ ++ Sbjct: 13 YAVGILKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAMVRE---AIKGG 69 Query: 108 QALILAPTRELAVQIQKGLLALGDYMNVQCHACIG---GTNVGE-DIRKLDYGQ-HVVAG 162 ++L + P R LA + Y + + IG G + G+ + R G ++ Sbjct: 70 KSLYVVPLRALAGE---------KYESFKKWEKIGLRIGISTGDYESRDEHLGDCDIIVT 120 Query: 163 TPGRVFDMIRRRSLRTRAIKMLVLDEA---DEMLNKGFKEQIYDVYRYLPPATQVVLISA 219 T + +IR R+ +A+ LV+DE D E + R + A +V+ +SA Sbjct: 121 TSEKADSLIRNRASWIKAVSCLVVDEIHLLDSEKRGATLEILVTKMRRMNKALRVIGLSA 180 Query: 220 TLPH--EILEM--TNKFMTD--PIRIL---------------------VKRDELTLEGIK 252 T P+ EI E + +++D P+ ++ VK +EL E + Sbjct: 181 TAPNVTEIAEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEECVA 240 Query: 253 Q-----FFVA----VEREEWKFDTLCDLY-DTLTITQAVIFCNTKRKVDWLTEKMREANF 302 + F + E+ K + Y + + +A++ N L E +R+ Sbjct: 241 ENGGVLVFESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKG-- 298 Query: 303 TVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII----NYDLPNNR 358 + H + +R + FR G +V+++T A G+++P +I+ +D + R Sbjct: 299 -AAFHHAGLLNGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKR 357 Query: 359 ---ELYIHRIGRSGRYG--RKGVAINFVKNDDIRI 388 Y GR+GR G +G AI V D I Sbjct: 358 IKVSEYKQMAGRAGRPGMDERGEAIIIVGKRDREI 392 >6DCR-A nrPDB Length = 694 Score = 35.8 bits (81), Expect = 0.036, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 33/71 (46%), Gaps = 12/71 (16%) Query: 317 ESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNN------------RELYIHR 364 E + E G +R+LI T + A+G P V+L+ D+ +LY Sbjct: 484 EQQLAEVHRGGARILIGTQMLAKGHHFPDVTLVALLDVDGALFSADFRSAERFAQLYTQV 543 Query: 365 IGRSGRYGRKG 375 GR+GR G++G Sbjct: 544 AGRAGRAGKQG 554 >4NL8-A nrPDB Length = 747 Score = 33.1 bits (74), Expect = 0.23, Method: Compositional matrix adjust. Identities = 21/74 (28%), Positives = 33/74 (44%), Gaps = 12/74 (16%) Query: 317 ESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNN------------RELYIHR 364 E + G +R+LI T + A+G P V+L+ D+ +LY Sbjct: 537 EEHLAAVHRGGARILIGTQMLAKGHHFPDVTLVSLLDVDGALFSADFRSAERFAQLYTQV 596 Query: 365 IGRSGRYGRKGVAI 378 GR+GR G++G I Sbjct: 597 SGRAGRAGKQGEVI 610 >4ON9-A nrPDB Length = 580 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 316 RESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRK 374 ++ I+ F+ SG +LI+T V G+D+ Q +L+I Y+ N I GR G K Sbjct: 465 QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSK 524 >4A4Z-A nrPDB Length = 997 Score = 32.7 bits (73), Expect = 0.30, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 8/77 (10%) Query: 304 VSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN----YDLPNNRE 359 ++ HG + +E I F G +VL +T+ +A GL++P ++I + +D RE Sbjct: 402 IAVHHGGLLPIVKELIEILFSKGFIKVLFATETFAMGLNLPTRTVIFSSIRKHDGNGLRE 461 Query: 360 L----YIHRIGRSGRYG 372 L + GR+GR G Sbjct: 462 LTPGEFTQMAGRAGRRG 478 >4BPB-A nrPDB Length = 698 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 1/60 (1%) Query: 316 RESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRK 374 ++ I+ F+ SG +LI+T V G+D+ Q +L+I Y+ N I GR G K Sbjct: 451 QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGRGRARGSK 510 >3TBK-A nrPDB Length = 555 Score = 32.7 bits (73), Expect = 0.33, Method: Compositional matrix adjust. Identities = 38/143 (26%), Positives = 63/143 (44%), Gaps = 22/143 (15%) Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMH-------------GDMPQKERESIMKEFR 324 T+ ++F T+ VD L +K E N +S + M ++ +++ FR Sbjct: 390 TKTILFVKTRALVDAL-KKWIEENPALSFLKPGILTGRGRTNRATGMTLPAQKCVLEAFR 448 Query: 325 -SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKN 383 SG + +LI+T V G+D+ + +L+I Y+ N I GR GR R + Sbjct: 449 ASGDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGR-GR-ARDSKCFLLTSS 506 Query: 384 DDIRILRDIEQYYSTQIDEMPMN 406 D+ IE+ + I E MN Sbjct: 507 ADV-----IEKEKANMIKEKIMN 524 >4A36-A nrPDB Length = 556 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 311 MPQKERESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSG 369 M ++ ++ F+ S +R+LI+T V G+D+ Q +L++ Y+ N I GR Sbjct: 436 MTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGR 495 Query: 370 RYGRKGVAI 378 G K + + Sbjct: 496 AAGSKCILV 504 >4A2Q-A nrPDB Length = 797 Score = 32.0 bits (71), Expect = 0.54, Method: Compositional matrix adjust. Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 311 MPQKERESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSG 369 M ++ ++ F+ S +R+LI+T V G+D+ Q +L++ Y+ N I GR Sbjct: 677 MTLPSQKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGR 736 Query: 370 RYGRKGVAI 378 G K + + Sbjct: 737 AAGSKCILV 745 >6QKC-A nrPDB Length = 915 Score = 32.0 bits (71), Expect = 0.56, Method: Compositional matrix adjust. Identities = 14/77 (18%), Positives = 37/77 (48%), Gaps = 4/77 (5%) Query: 224 EILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIF 283 E+++ + FM+ I I++K+ + + G+ F + E W +C ++ + ++ + Sbjct: 509 EVIDFSKPFMSLGISIMIKKPQKSKPGVFSFLDPLAYEIW----MCIVFAYIGVSVVLFL 564 Query: 284 CNTKRKVDWLTEKMREA 300 + +W +E+ E Sbjct: 565 VSRFSPYEWHSEEFEEG 581 >4A2W-A nrPDB Length = 936 Score = 32.0 bits (71), Expect = 0.56, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Query: 316 RESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRK 374 ++ ++ F+ S +R+LI+T V G+D+ Q +L++ Y+ N I GR G K Sbjct: 682 QKGVLDAFKTSKDNRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGRGRAAGSK 741 Query: 375 GVAI 378 + + Sbjct: 742 CILV 745 >6F4A-B nrPDB Length = 644 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 24/100 (24%), Positives = 44/100 (44%), Gaps = 4/100 (4%) Query: 244 DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFT 303 D+LT+ ++ V EE L Y +L V+ + K +D E ++ Sbjct: 298 DKLTINEYERMGKLVVEEE----ALTKGYHSLKKGDCVVAFSKKAILDLKLEIEKKTELK 353 Query: 304 VSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDV 343 + ++G +P + R F SG +LI++D GL++ Sbjct: 354 AAVIYGSLPPETRVKQANLFNSGEFDILIASDAIGMGLNL 393 >2XSZ-D nrPDB Length = 378 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 14/67 (20%) Query: 73 IKGRDVIAQSQSGTGKTATF--------------SISVLQCLDIQVRETQALILAPTREL 118 I GR V+ Q GTGKTA +I+ + +++ +T+AL A R + Sbjct: 83 IAGRAVLIAGQPGTGKTAIAMGMAQALGPDTPFTAIAGSEIFSLEMSKTEALTQAFRRSI 142 Query: 119 AVQIQKG 125 V+I++G Sbjct: 143 GVRIKEG 149 >2BMF-A nrPDB Length = 451 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 30/116 (25%), Positives = 50/116 (43%), Gaps = 14/116 (12%) Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYM 133 K R I G GKT + ++++ + R + LILAPTR +A ++++ L L + Sbjct: 18 KKRLTIMDLHPGAGKTKRYLPAIVR--EAIKRGLRTLILAPTRVVAAEMEEALRGLP--I 73 Query: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEA 189 Q A IR G+ +V F M +R ++++DEA Sbjct: 74 RYQTPA----------IRAEHTGREIVDLMCHATFTMRLLSPIRVPNYNLIIMDEA 119 >2JLW-A nrPDB Length = 451 Score = 29.3 bits (64), Expect = 3.3, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLAL 129 K R I G GKT S+++ + R + LILAPTR +A ++++ L L Sbjct: 18 KKRLTIMDLHPGAGKTKRILPSIVR--EALKRRLRTLILAPTRVVAAEMEEALRGL 71 >1YKS-A nrPDB Length = 440 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 31/149 (20%), Positives = 61/149 (40%), Gaps = 14/149 (9%) Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYM 133 KG + G GKT F +L + R + L+LAPTR + ++++ L Sbjct: 7 KGMTTVLDFHPGAGKTRRFLPQILA--ECARRRLRTLVLAPTRVVLSEMKEAFHGLDVKF 64 Query: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193 + Q + G G ++ +D H + M+ R +++++DEA + Sbjct: 65 HTQAFSAHGS---GREV--IDAMCHATL-----TYRML--EPTRVVNWEVIIMDEAHFLD 112 Query: 194 NKGFKEQIYDVYRYLPPATQVVLISATLP 222 + + +R + +L++AT P Sbjct: 113 PASIAARGWAAHRARANESATILMTATPP 141 >6BN7-A nrPDB Length = 864 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 125 GLLALGDYMNVQCHACIGGTNVGE 148 GL LG+++NV CH + N+GE Sbjct: 720 GLFHLGEFVNVFCHGSLVMQNLGE 743 >4L6H-A nrPDB Length = 789 Score = 28.9 bits (63), Expect = 4.1, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 22/34 (64%) Query: 51 RGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQS 84 R I+ F K SA+ Q+AI+++ K + V+A S S Sbjct: 327 RNIWKTDFAKASAVVQKAIEKVGKDKVVVATSSS 360 >6FNP-B nrPDB Length = 300 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 182 KMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILE 227 ++++LDE+ ML+ KEQI D+ R + + +IS T H++ E Sbjct: 181 QVIILDESTSMLDPEGKEQILDLVRKIKEDNNLTVISIT--HDLEE 224 >5N8S-A nrPDB Length = 944 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 24/98 (24%), Positives = 44/98 (44%), Gaps = 19/98 (19%) Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII--------NY 352 + V +H M E++++ + +G +V+IST + + + V +I NY Sbjct: 456 HMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNY 515 Query: 353 DLPNN----RELYI------HRIGRSGRYGRKGVAINF 380 D+ N E+++ R GR+GR R G+ N Sbjct: 516 DIETNIQSLDEVWVTKANTQQRRGRAGRV-RPGICYNL 552 >2WZQ-A nrPDB Length = 619 Score = 28.5 bits (62), Expect = 4.9, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 29/56 (51%), Gaps = 2/56 (3%) Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLAL 129 K R I G GKT S+++ + R + LILAPTR +A ++++ L L Sbjct: 186 KKRLTIMDLHPGAGKTKRILPSIVR--EALKRRLRTLILAPTRVVAAEMEEALRGL 239 >2JGD-B nrPDB Length = 933 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 40/88 (45%), Gaps = 13/88 (14%) Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEA------------DEMLNKGFKEQIYDV 204 Q V TP +V+ M+RR++LR ++V+ +E+ N F I ++ Sbjct: 747 QVCVPSTPAQVYHMLRRQALRGMRRPLVVMSPKSLLRHPLAVSSLEELANGTFLPAIGEI 806 Query: 205 YRYLPPATQ-VVLISATLPHEILEMTNK 231 P + VV+ S + +++LE K Sbjct: 807 DELDPKGVKRVVMCSGKVYYDLLEQRRK 834 >4XGT-A nrPDB Length = 993 Score = 27.7 bits (60), Expect = 8.4, Method: Compositional matrix adjust. Identities = 36/168 (21%), Positives = 65/168 (38%), Gaps = 15/168 (8%) Query: 56 YGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115 Y F K Q ++ I + V+ + + GKT ++ QCL + + + +P Sbjct: 64 YSF-KLDPFQALSVASIEREESVLVSAHTSAGKTVVAEYAIAQCLK---KNQRVIYTSPI 119 Query: 116 RELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRS 175 + L+ Q Y + Q G G+ ++ + T + M+ R S Sbjct: 120 KALSNQ---------KYRDFQAEFGDVGLMTGD--VTINPTASCLVMTTEILRSMLYRGS 168 Query: 176 LRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPH 223 R + +V DE M +K + LP + V +SAT+P+ Sbjct: 169 EIMREVAWVVFDEIHYMRDKIRGVVWEETIILLPDKVRYVFLSATIPN 216 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2HYI-C nrPDB 557 e-159 3EIQ-A nrPDB 498 e-141 4BRW-A nrPDB 449 e-126 2VSX-A nrPDB 447 e-126 5ANR-B nrPDB 441 e-124 5IVL-B nrPDB 433 e-122 4NHO-A nrPDB 433 e-122 3JCR-F nrPDB 426 e-119 1XTI-A nrPDB 418 e-117 6CZ5-A nrPDB 412 e-115 5DTU-A nrPDB 407 e-114 2I4I-A nrPDB 406 e-114 4D25-A nrPDB 406 e-114 1HV8-A nrPDB 405 e-113 5SUQ-A nrPDB 403 e-113 5SUP-A nrPDB 402 e-112 2DB3-A nrPDB 401 e-112 3PEW-A nrPDB 395 e-110 6B4I-E nrPDB 395 e-110 6CB1-p nrPDB 390 e-109 4KBG-A nrPDB 367 e-102 3FHO-A nrPDB 365 e-101 5ZWN-y nrPDB 354 5e-98 4W7S-A nrPDB 352 1e-97 4LJY-A nrPDB 348 3e-96 2Z0M-A nrPDB 337 4e-93 3SQW-A nrPDB 319 1e-87 3I62-A nrPDB 316 1e-86 5ZBZ-A nrPDB 288 2e-78 3BOR-A nrPDB 288 3e-78 6CRM-A nrPDB 275 2e-74 4CDG-A nrPDB 270 8e-73 1WRB-A nrPDB 264 3e-71 1OYY-A nrPDB 261 6e-70 5GJU-A nrPDB 261 6e-70 1QVA-A nrPDB 260 9e-70 4PX9-A nrPDB 253 1e-67 2GXQ-A nrPDB 252 2e-67 1T6N-A nrPDB 251 3e-67 1VEC-A nrPDB 251 5e-67 3FE2-A nrPDB 247 5e-66 5H1Y-A nrPDB 243 1e-64 3BER-A nrPDB 242 2e-64 6AIC-A nrPDB 240 8e-64 5GVS-A nrPDB 238 3e-63 3IUY-A nrPDB 233 1e-61 2OXC-A nrPDB 231 5e-61 1Q0U-A nrPDB 229 2e-60 5AGA-A nrPDB 224 8e-59 3FMO-B nrPDB 220 7e-58 3FHC-B nrPDB 220 7e-58 2KBE-A nrPDB 220 1e-57 2PL3-A nrPDB 215 4e-56 3LY5-A nrPDB 212 2e-55 4Q48-A nrPDB 210 6e-55 2WWY-A nrPDB 208 3e-54 5V9X-A nrPDB 207 6e-54 1GM5-A nrPDB 202 3e-52 3DKP-A nrPDB 196 2e-50 5LST-A nrPDB 190 7e-49 5JCF-A nrPDB 118 4e-27 4GL2-A nrPDB 115 5e-26 1WP9-A nrPDB 112 3e-25 6G19-A nrPDB 108 3e-24 5JBJ-A nrPDB 95 6e-20 1D9Z-A nrPDB 93 2e-19 5TNU-A nrPDB 92 4e-19 2NMV-A nrPDB 91 1e-18 2FWR-A nrPDB 90 1e-18 Sequences not found previously or not previously below threshold: 5LBA-B nrPDB 192 2e-49 5LB8-A nrPDB 192 2e-49 2P6R-A nrPDB 137 1e-32 2ZJ8-A nrPDB 135 5e-32 2VA8-A nrPDB 127 1e-29 6C90-A nrPDB 96 3e-20 4XGT-A nrPDB 83 2e-16 3P4X-A nrPDB 80 2e-15 3TBK-A nrPDB 78 7e-15 1C4O-A nrPDB 77 2e-14 6DCR-A nrPDB 75 6e-14 4BPB-A nrPDB 75 7e-14 4ON9-A nrPDB 74 9e-14 5VHD-D nrPDB 73 2e-13 6F4A-B nrPDB 72 3e-13 4NL8-A nrPDB 70 2e-12 5WX1-A nrPDB 69 4e-12 6HEG-A nrPDB 68 5e-12 4CBI-A nrPDB 67 1e-11 4A4Z-A nrPDB 66 3e-11 2OCA-A nrPDB 65 7e-11 5WSO-A nrPDB 64 1e-10 5I8Q-A nrPDB 63 2e-10 5GM6-Y nrPDB 63 3e-10 5D0U-A nrPDB 63 3e-10 3B6E-A nrPDB 62 4e-10 6FA9-A nrPDB 62 4e-10 4A2W-A nrPDB 62 5e-10 4A2Q-A nrPDB 61 8e-10 4A36-A nrPDB 60 1e-09 6I3O-A nrPDB 59 4e-09 6BOG-A nrPDB 57 1e-08 5N8S-A nrPDB 56 2e-08 3RC8-A nrPDB 55 5e-08 4B6E-A nrPDB 55 6e-08 4OK6-A nrPDB 54 1e-07 2ZJO-A nrPDB 54 1e-07 3MWY-W nrPDB 54 1e-07 6FTX-W nrPDB 53 2e-07 6ID1-V nrPDB 53 2e-07 3H1T-A nrPDB 53 3e-07 5XDR-A nrPDB 53 3e-07 3DIN-A nrPDB 53 3e-07 5X0Y-O nrPDB 51 7e-07 5WDX-A nrPDB 51 9e-07 5JXR-A nrPDB 49 3e-06 5JXT-B nrPDB 49 3e-06 5HZR-A nrPDB 48 5e-06 5K8T-A nrPDB 47 2e-05 2WV9-A nrPDB 46 3e-05 1YKS-A nrPDB 46 4e-05 2V8O-A nrPDB 45 6e-05 2BMF-A nrPDB 45 6e-05 3BXZ-A nrPDB 45 7e-05 3LLM-A nrPDB 44 1e-04 2Z83-A nrPDB 44 1e-04 2JLW-A nrPDB 43 2e-04 1Z6A-A nrPDB 43 2e-04 1TF2-A nrPDB 43 2e-04 2WZQ-A nrPDB 43 3e-04 5EUL-A nrPDB 43 3e-04 1Z5Z-A nrPDB 43 3e-04 5GN1-A nrPDB 42 5e-04 2QEQ-A nrPDB 42 5e-04 4QQW-A nrPDB 41 6e-04 4UAQ-A nrPDB 41 0.001 1RIF-A nrPDB 41 0.001 1NLZ-A nrPDB 40 0.002 1NL3-A nrPDB 40 0.002 2V6J-A nrPDB 38 0.005 6FWS-A nrPDB 38 0.009 5K9T-A nrPDB 38 0.011 2FSI-A nrPDB 37 0.017 1Z3I-X nrPDB 37 0.019 5H8W-A nrPDB 36 0.021 2FZ4-A nrPDB 36 0.022 3CRV-A nrPDB 35 0.074 3A2B-A nrPDB 35 0.082 5TV4-A nrPDB 32 0.38 5O6D-A nrPDB 32 0.62 6D00-1 nrPDB 31 0.86 2V1U-A nrPDB 31 0.93 5FL3-A nrPDB 30 1.5 4I5O-A nrPDB 30 1.7 1UB3-A nrPDB 30 1.9 2IPC-A nrPDB 30 2.5 5V8F-E nrPDB 30 2.5 3M6A-A nrPDB 30 2.6 6F5D-G nrPDB 30 2.7 4ZCF-C nrPDB 30 3.0 3ACB-A nrPDB 29 3.2 4HZU-A nrPDB 29 3.3 4B3F-X nrPDB 29 3.7 1UM8-A nrPDB 28 5.4 3S1A-A nrPDB 28 7.3 5ZQT-A nrPDB 28 8.4 4TLD-A nrPDB 28 8.5 1SXJ-B nrPDB 28 9.1 >2HYI-C nrPDB Length = 413 Score = 557 bits (1435), Expect = e-159, Method: Composition-based stats. Identities = 411/411 (100%), Positives = 411/411 (100%) Query: 1 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK Sbjct: 1 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60 Query: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV Sbjct: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA Sbjct: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 Query: 181 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL Sbjct: 181 IKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240 Query: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA Sbjct: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA 300 Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL Sbjct: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360 Query: 361 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI Sbjct: 361 YIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 >3EIQ-A nrPDB Length = 414 Score = 498 bits (1283), Expect = e-141, Method: Composition-based stats. Identities = 271/406 (66%), Positives = 328/406 (80%), Gaps = 1/406 (0%) Query: 7 MATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQ 66 M+ S +R R + M S ++ +FD M L E LLRGIYAYGFEKPSAIQQ Sbjct: 9 MSASQDSRSRDNGPDGMEPEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQ 68 Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 RAI IKG DVIAQ+QSGTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK + Sbjct: 69 RAILPCIKGYDVIAQAQSGTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVV 128 Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185 +ALGDYM CHACIGGTNV +++KL H++ GTPGRVFDM+ RR L + IKM V Sbjct: 129 MALGDYMGASCHACIGGTNVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFV 188 Query: 186 LDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDE 245 LDEADEML++GFK+QIYD+++ L TQVVL+SAT+P ++LE+T KFM DPIRILVK++E Sbjct: 189 LDEADEMLSRGFKDQIYDIFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKKEE 248 Query: 246 LTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVS 305 LTLEGI+QF++ VEREEWK DTLCDLY+TLTITQAVIF NT+RKVDWLTEKM +FTVS Sbjct: 249 LTLEGIRQFYINVEREEWKLDTLCDLYETLTITQAVIFINTRRKVDWLTEKMHARDFTVS 308 Query: 306 SMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRI 365 +MHGDM QKER+ IM+EFRSG+SRVLI+TD+ ARG+DV QVSL+INYDLP NRE YIHRI Sbjct: 309 AMHGDMDQKERDVIMREFRSGSSRVLITTDLLARGIDVQQVSLVINYDLPTNRENYIHRI 368 Query: 366 GRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 GR GR+GRKGVAIN V +D R LRDIE +Y+T I+EMP+NVADLI Sbjct: 369 GRGGRFGRKGVAINMVTEEDKRTLRDIETFYNTSIEEMPLNVADLI 414 >4BRW-A nrPDB Length = 377 Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats. Identities = 150/369 (40%), Positives = 226/369 (61%), Gaps = 2/369 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 TF+ L+ +LL GI+ GFEKPS IQ+ AI I GRD++A++++GTGKTA F I L+ Sbjct: 2 TFEDFYLKRELLMGIFEAGFEKPSPIQEEAIPVAITGRDILARAKNGTGKTAAFVIPTLE 61 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158 + ++ + QALI+ PTRELA+Q + + LG + + C GGTN+ +DI +L+ H Sbjct: 62 KVKPKLNKIQALIMVPTRELALQTSQVVRTLGKHCGISCMVTTGGTNLRDDILRLNETVH 121 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 ++ GTPGRV D+ R+ + ++DEAD+ML++ FK I + +LPP Q +L S Sbjct: 122 ILVGTPGRVLDLASRKVADLSDCSLFIMDEADKMLSRDFKTIIEQILSFLPPTHQSLLFS 181 Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 AT P + E +K + P I + +ELTL+GI Q++ VE E K L L+ L I Sbjct: 182 ATFPLTVDEFMDKHLHKPYEINL-MEELTLKGITQYYAFVE-ERQKLHCLNTLFSKLQIN 239 Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 QA+IFCN+ +V+ L +K+ + ++ H M Q+ER + EFR G R L+ +D+ Sbjct: 240 QAIIFCNSTNRVELLAKKITDLGYSCYYSHARMKQQERNKVFHEFRQGKVRTLVCSDLLT 299 Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYST 398 RG+D+ V+++IN+D P E Y+HRIGRSGR+G G+AIN + +D L IEQ T Sbjct: 300 RGIDIQAVNVVINFDFPKTAETYLHRIGRSGRFGHLGLAINLINWNDRFNLYKIEQELGT 359 Query: 399 QIDEMPMNV 407 +I +P + Sbjct: 360 EIAAIPATI 368 >2VSX-A nrPDB Length = 395 Score = 447 bits (1149), Expect = e-126, Method: Composition-based stats. Identities = 244/394 (61%), Positives = 318/394 (80%), Gaps = 3/394 (0%) Query: 20 EEDMTKVEFET--SEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRD 77 E +T +E + V FD M L E+LLRG++ YGFE+PSAIQQRAI II+G D Sbjct: 2 SEGITDIEESQIQTNYDKVVYKFDDMELDENLLRGVFGYGFEEPSAIQQRAIMPIIEGHD 61 Query: 78 VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQC 137 V+AQ+QSGTGKT TFSI+ LQ +D V+ QAL+LAPTRELA+QIQK ++AL +M+++ Sbjct: 62 VLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKV 121 Query: 138 HACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGF 197 HACIGGT+ ED L Q +V GTPGRVFD I+RR RT IKM +LDEADEML+ GF Sbjct: 122 HACIGGTSFVEDAEGLRDAQ-IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGF 180 Query: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257 KEQIY ++ LPP TQVVL+SAT+P+++LE+T KFM +P+RILVK+DELTLEGIKQF+V Sbjct: 181 KEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILVKKDELTLEGIKQFYVN 240 Query: 258 VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE 317 VE EE+K++ L DLYD++++TQAVIFCNT+RKV+ LT K+R FTVS+++ D+PQ+ER+ Sbjct: 241 VEEEEYKYECLTDLYDSISVTQAVIFCNTRRKVEELTTKLRNDKFTVSAIYSDLPQQERD 300 Query: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377 +IMKEFRSG+SR+LISTD+ ARG+DV QVSL+INYDLP N+E YIHRIGR GR+GRKGVA Sbjct: 301 TIMKEFRSGSSRILISTDLLARGIDVQQVSLVINYDLPANKENYIHRIGRGGRFGRKGVA 360 Query: 378 INFVKNDDIRILRDIEQYYSTQIDEMPMNVADLI 411 INFV N+D+ +R++E++YSTQI+E+P ++A L+ Sbjct: 361 INFVTNEDVGAMRELEKFYSTQIEELPSDIATLL 394 >5ANR-B nrPDB Length = 378 Score = 441 bits (1134), Expect = e-124, Method: Composition-based stats. Identities = 139/369 (37%), Positives = 233/369 (63%), Gaps = 3/369 (0%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F+ L+ +LL GI+ G+EKPS IQ+ +I + GRD++A++++GTGK+ + I +L+ Sbjct: 7 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 66 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMN-VQCHACIGGTNVGEDIRKLDYGQH 158 LD++ QA+++ PTRELA+Q+ + + + +M + A GGTN+ +DI +LD H Sbjct: 67 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 126 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 VV TPGR+ D+I++ + ++M+VLDEAD++L++ F + + D+ LP Q++L S Sbjct: 127 VVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYS 186 Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 AT P + + N + P I + +ELTL+G+ Q++ V E K L L+ L I Sbjct: 187 ATFPLSVQKFMNSHLQKPYEINL-MEELTLKGVTQYYAYVT-ERQKVHCLNTLFSRLQIN 244 Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 Q++IFCN+ ++V+ L +K+ + ++ +H M Q+ R + +FR+G R L+ TD++ Sbjct: 245 QSIIFCNSSQRVELLAKKISQLGYSCFYIHAKMRQEHRNRVFHDFRNGLCRNLVCTDLFT 304 Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYST 398 RG+D+ V+++IN+D P E Y+HRIGRSGR+G G+AIN + DD L+ IE+ T Sbjct: 305 RGIDIQAVNVVINFDFPKLAETYLHRIGRSGRFGHLGLAINLITYDDRFNLKSIEEQLGT 364 Query: 399 QIDEMPMNV 407 +I +P N+ Sbjct: 365 EIKPIPSNI 373 >5IVL-B nrPDB Length = 429 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 147/370 (39%), Positives = 229/370 (61%), Gaps = 2/370 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 TF +GL +++++ I GFE+ + IQ + I ++ +DVI Q+Q+GTGKTA F I +++ Sbjct: 3 TFQELGLSQEVMKAIERMGFEETTPIQAKTIPLSLQNKDVIGQAQTGTGKTAAFGIPIVE 62 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158 +D++ QAL++APTRELA+Q+ + L +G V+ GG ++ IR L H Sbjct: 63 KVDVKNGAIQALVVAPTRELAIQVSEELYKIGAVKRVRVLPIYGGQDIERQIRALKKHPH 122 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 V+ GTPGR+ D I R +LR + +VLDEADEMLN GF E I + ++P Q +L S Sbjct: 123 VIVGTPGRIIDHINRGTLRLEHVHTVVLDEADEMLNMGFIEDIEAILSHVPAERQTLLFS 182 Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 AT+P I + +FM +P + VK E+T+ I+Q+++ V E+ KFD L L D Sbjct: 183 ATMPDPIRRIAERFMNEPELVKVKAKEMTVPNIQQYYLEV-HEKKKFDILTRLLDIQAPE 241 Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 A++F TKR+VD L E + + +HGD+ Q +R S++++F+ GA +L++TDV A Sbjct: 242 LAIVFGRTKRRVDELAEALNLRGYAAEGIHGDLSQAKRLSVLRKFKEGAIEILVATDVAA 301 Query: 339 RGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYST 398 RGLD+ V+ + N+D+P + E Y+HRIGR+GR G+ GVA+ FV +I L IE+ Sbjct: 302 RGLDISGVTHVYNFDIPQDPESYVHRIGRTGRAGKTGVAMTFVTPREIGQLHHIERTTKR 361 Query: 399 QIDEM-PMNV 407 +++ M P + Sbjct: 362 KMERMKPPTL 371 >4NHO-A nrPDB Length = 488 Score = 433 bits (1113), Expect = e-122, Method: Composition-based stats. Identities = 115/421 (27%), Positives = 209/421 (49%), Gaps = 37/421 (8%) Query: 25 KVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQS 84 + + + + ++ L +L I G+++P+ IQ++AI ++ RD+I +++ Sbjct: 46 SITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAET 105 Query: 85 GTGKTATFSISVL---------QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 G+GKTA F I +L ++ + A+ILAPTRELA QI++ + G + + Sbjct: 106 GSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGI 165 Query: 136 QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK 195 + A IGG + + +L G +V TPGR+ D++ R L +VLDEAD M++ Sbjct: 166 RTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDM 225 Query: 196 GFKEQIYDVYRYLP--------------------------PATQVVLISATLPHEILEMT 229 GF+ + + ++P Q V+ +AT+P + + Sbjct: 226 GFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLA 285 Query: 230 NKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRK 289 ++ P + + E ++Q V + E K L + + +IF N K+ Sbjct: 286 RSYLRRPAVVYIGSAGKPHERVEQK-VFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKG 344 Query: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349 D L + + + + ++HG Q++RE + ++GA +L++TDV RG+D+ VS++ Sbjct: 345 CDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMV 404 Query: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQ-YYSTQIDEMPMNVA 408 +NYD+ N E YIHRIGR+GR G+ GVAI F+ +D + +++Q + + P +A Sbjct: 405 VNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELA 464 Query: 409 D 409 + Sbjct: 465 N 465 >3JCR-F nrPDB Length = 820 Score = 426 bits (1095), Expect = e-119, Method: Composition-based stats. Identities = 115/421 (27%), Positives = 209/421 (49%), Gaps = 37/421 (8%) Query: 25 KVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQS 84 + + + + ++ L +L I G+++P+ IQ++AI ++ RD+I +++ Sbjct: 378 SITTKGGKIPNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDIIGVAET 437 Query: 85 GTGKTATFSISVL---------QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 G+GKTA F I +L ++ + A+ILAPTRELA QI++ + G + + Sbjct: 438 GSGKTAAFLIPLLVWITTLPKIDRIEESDQGPYAIILAPTRELAQQIEEETIKFGKPLGI 497 Query: 136 QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK 195 + A IGG + + +L G +V TPGR+ D++ R L +VLDEAD M++ Sbjct: 498 RTVAVIGGISREDQGFRLRMGCEIVIATPGRLIDVLENRYLVLSRCTYVVLDEADRMIDM 557 Query: 196 GFKEQIYDVYRYLP--------------------------PATQVVLISATLPHEILEMT 229 GF+ + + ++P Q V+ +AT+P + + Sbjct: 558 GFEPDVQKILEHMPVSNQKPDTDEAEDPEKMLANFESGKHKYRQTVMFTATMPPAVERLA 617 Query: 230 NKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRK 289 ++ P + + E ++Q V + E K L + + +IF N K+ Sbjct: 618 RSYLRRPAVVYIGSAGKPHERVEQK-VFLMSESEKRKKLLAILEQGFDPPIIIFVNQKKG 676 Query: 290 VDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI 349 D L + + + + ++HG Q++RE + ++GA +L++TDV RG+D+ VS++ Sbjct: 677 CDVLAKSLEKMGYNACTLHGGKGQEQREFALSNLKAGAKDILVATDVAGRGIDIQDVSMV 736 Query: 350 INYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQ-YYSTQIDEMPMNVA 408 +NYD+ N E YIHRIGR+GR G+ GVAI F+ +D + +++Q + + P +A Sbjct: 737 VNYDMAKNIEDYIHRIGRTGRAGKSGVAITFLTKEDSAVFYELKQAILESPVSSCPPELA 796 Query: 409 D 409 + Sbjct: 797 N 797 >1XTI-A nrPDB Length = 391 Score = 418 bits (1076), Expect = e-117, Method: Composition-based stats. Identities = 141/373 (37%), Positives = 220/373 (58%), Gaps = 6/373 (1%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +LLR I GFE PS +Q I Q I G DV+ Q++SG GKTA F ++ LQ Sbjct: 10 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 69 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQ- 157 L+ + L++ TRELA QI K YM NV+ GG ++ +D L Sbjct: 70 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 129 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVL 216 H+V GTPGR+ + R +SL + IK +LDE D+ML + + + +++R P QV++ Sbjct: 130 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 189 Query: 217 ISATLPHEILEMTNKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275 SATL EI + KFM DP+ I V + +LTL G++Q++V ++ E K L DL D L Sbjct: 190 FSATLSKEIRPVCRKFMQDPMEIFVDDETKLTLHGLQQYYVKLKDNE-KNRKLFDLLDVL 248 Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTD 335 Q VIF + ++ L + + E NF ++H MPQ+ER S ++F+ R+L++T+ Sbjct: 249 EFNQVVIFVKSVQRCIALAQLLVEQNFPAIAIHRGMPQEERLSRYQQFKDFQRRILVATN 308 Query: 336 VWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND-DIRILRDIEQ 394 ++ RG+D+ +V++ NYD+P + + Y+HR+ R+GR+G KG+AI FV ++ D +IL D++ Sbjct: 309 LFGRGMDIERVNIAFNYDMPEDSDTYLHRVARAGRFGTKGLAITFVSDENDAKILNDVQD 368 Query: 395 YYSTQIDEMPMNV 407 + I E+P + Sbjct: 369 RFEVNISELPDEI 381 >6CZ5-A nrPDB Length = 480 Score = 412 bits (1058), Expect = e-115, Method: Composition-based stats. Identities = 137/433 (31%), Positives = 220/433 (50%), Gaps = 32/433 (7%) Query: 10 SGSARKRLLKEEDMTKVEFETSEEVDV----------TPTFDTMGLREDLLRGIYAYGFE 59 ++ L T + FE +++ V +F + + E ++ I + Sbjct: 15 PSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYT 74 Query: 60 KPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL------------------D 101 +P+ +Q+ AI I + RD++A +Q+G GKTA F + +L + Sbjct: 75 RPTPVQKHAIPIIKEKRDLMACAQTGCGKTAAFLLPILSQIYSDGPGEALRAMKENGRYG 134 Query: 102 IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161 + + +L+LAPTRELAVQI + V+ GG ++G+ IR L+ G H++ Sbjct: 135 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 194 Query: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPPA--TQVVLI 217 TPGR+ DM+ R + K LVLDEAD ML+ GF+ QI + +PP ++ Sbjct: 195 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 254 Query: 218 SATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI 277 SAT P EI + F+ + I + V R T E I Q V VE + + L L T Sbjct: 255 SATFPKEIQMLARDFLDEYIFLAVGRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKD 314 Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337 + ++F TK+ D L + + + +S+HGD Q++RE + +FRSG S +L++T V Sbjct: 315 SLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDREEALHQFRSGKSPILVATAVA 374 Query: 338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYS 397 ARGLD+ V +IN+DLP++ E Y+HRIGR+GR G G+A +F +I I +D+ Sbjct: 375 ARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLV 434 Query: 398 TQIDEMPMNVADL 410 E+P + ++ Sbjct: 435 EAKQEVPSWLENM 447 >5DTU-A nrPDB Length = 475 Score = 407 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 115/418 (27%), Positives = 214/418 (51%), Gaps = 35/418 (8%) Query: 25 KVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQS 84 + + + ++ GL LL +Y G+++P+ IQ+ AI ++ RD+I + + Sbjct: 29 GISTKGGSIPNPMRNWEESGLPRRLLDIVYRVGYDEPTPIQRAAIPIALQARDLIGVAVT 88 Query: 85 GTGKTATFSISVLQCLD--------IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQ 136 G+GKTA F + +L + + ALILAPTREL QI+ D + Sbjct: 89 GSGKTAAFLLPLLVYISELPPLTEYNKNDGPYALILAPTRELVQQIESEARKFADPLGFT 148 Query: 137 CHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG 196 + +GG ++ E L G ++ TPGR+ D I RR L +++DEAD M+++G Sbjct: 149 VVSIVGGHSLEEQAFALRNGAEIIVATPGRLVDCIERRLLVFSQCCYVIMDEADRMIDQG 208 Query: 197 FKEQIYDVYRYLP-------------------------PATQVVLISATLPHEILEMTNK 231 F+E + + LP Q ++ +AT+P + ++ K Sbjct: 209 FEEPLTKILDALPVSNEKPDTEDAENPQLMSRYLGGRDRYRQTMMYTATMPPTVEKIAKK 268 Query: 232 FMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVI-FCNTKRKV 290 ++ P + + ++ ++Q + E+ + L ++ ++ +I F N KR Sbjct: 269 YLRRPAIVTIGNAGEAVDTVEQRVEFIAGEDKRKRRLQEILNSGQFKPPIIVFVNIKRNC 328 Query: 291 DWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350 + + + ++ F+ ++HG Q++RE+ + R+G + +L++TD+ RG+DVP VSL++ Sbjct: 329 EMVAKDIKSWGFSTVTLHGSKTQEQREASLAALRNGQAHILVATDLAGRGIDVPDVSLVV 388 Query: 351 NYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYS-TQIDEMPMNV 407 N+++P+ E Y HRIGR+GR G+ GVAI F+ N+D ++ D++Q S + I ++P + Sbjct: 389 NFNMPSTIEAYTHRIGRTGRAGKSGVAITFLGNEDADVMYDLKQIISKSSISKVPEEL 446 >2I4I-A nrPDB Length = 417 Score = 406 bits (1044), Expect = e-114, Method: Composition-based stats. Identities = 134/409 (32%), Positives = 214/409 (52%), Gaps = 22/409 (5%) Query: 24 TKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQ 83 + VE + +F + + E ++ I + +P+ +Q+ AI I + RD++A +Q Sbjct: 1 SMVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYTRPTPVQKHAIPIIKEKRDLMACAQ 60 Query: 84 SGTGKTATFSISVLQCL------------------DIQVRETQALILAPTRELAVQIQKG 125 +G+GKTA F + +L + + + +L+LAPTRELAVQI + Sbjct: 61 TGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYGRRKQYPISLVLAPTRELAVQIYEE 120 Query: 126 LLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185 V+ GG ++G+ IR L+ G H++ TPGR+ DM+ R + K LV Sbjct: 121 ARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLVATPGRLVDMMERGKIGLDFCKYLV 180 Query: 186 LDEADEMLNKGFKEQIYDVYRY--LPPA--TQVVLISATLPHEILEMTNKFMTDPIRILV 241 LDEAD ML+ GF+ QI + +PP ++ SAT P EI + F+ + I + V Sbjct: 181 LDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMFSATFPKEIQMLARDFLDEYIFLAV 240 Query: 242 KRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREAN 301 R T E I Q V VE + + L L T + ++F TK+ D L + + Sbjct: 241 GRVGSTSENITQKVVWVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEG 300 Query: 302 FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELY 361 + +S+HGD Q++RE + +FRSG S +L++T V ARGLD+ V +IN+DLP++ E Y Sbjct: 301 YACTSIHGDRSQRDREEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEY 360 Query: 362 IHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVADL 410 +HRIGR+GR G G+A +F +I I +D+ E+P + ++ Sbjct: 361 VHRIGRTGRVGNLGLATSFFNERNINITKDLLDLLVEAKQEVPSWLENM 409 >4D25-A nrPDB Length = 434 Score = 406 bits (1044), Expect = e-114, Method: Composition-based stats. Identities = 121/428 (28%), Positives = 214/428 (50%), Gaps = 25/428 (5%) Query: 1 MATTATMATSGSARKRLLKEEDMTKVEFETSEE----------VDVTPTFDTMGLREDLL 50 M T + + + + F+ + +F+T LR+ +L Sbjct: 3 MGVTYVPPEPTNDETEIFSSTISSGINFDKFDHIAVKVSGENPPRPIESFETANLRKYVL 62 Query: 51 RGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL---------D 101 + G+ KP+ IQ+ AI I+ GRD++ +Q+G+GKTA F + ++ L + Sbjct: 63 DNVLKAGYRKPTPIQKNAIPIIMSGRDLMGCAQTGSGKTAAFLVPIINMLLQDPKDLISE 122 Query: 102 IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161 + Q +I++PTREL +QI ++ GGT V + G H++ Sbjct: 123 NGCAQPQVIIVSPTRELTLQIFNEARKFSYGSVLKVAVAYGGTAVRHQGDNIARGCHILV 182 Query: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY----LPPATQVVLI 217 TPGR+ D + R + +++ +VLD+AD ML+ GF I + + Q ++ Sbjct: 183 ATPGRLHDFVERNRVSFGSVRFVVLDQADCMLDMGFMPSIEKMMLHPTMVETTKRQTLMF 242 Query: 218 SATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI 277 SAT P +I + +F+ + + + V ++Q F+ V + E K ++L L + Sbjct: 243 SATFPEDIQHLAGRFLNNYLFVAVGIVGGASTDVEQIFIEVTKYE-KRNSLKQLIEENDG 301 Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337 + ++F TKR D++ + E SS+HGD Q+ERE ++ F+SG +L++T V Sbjct: 302 KRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVATAVA 361 Query: 338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND-DIRILRDIEQYY 396 ARGLD+ V +++NYDLP + + Y+HRIGR+GR G +G A++F +D D+ ++ D+ + Sbjct: 362 ARGLDIKNVDIVVNYDLPKSIDEYVHRIGRTGRVGNRGKAVSFYDSDQDLALVADLSKIL 421 Query: 397 STQIDEMP 404 +P Sbjct: 422 RQADQSVP 429 >1HV8-A nrPDB Length = 367 Score = 405 bits (1042), Expect = e-113, Method: Composition-based stats. Identities = 131/366 (35%), Positives = 215/366 (58%), Gaps = 9/366 (2%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGR-DVIAQSQSGTGKTATFSISVL 97 F+ + L +++L I GFEKP+ IQ + I + +++AQ+++G+GKTA+F+I ++ Sbjct: 7 NFNELNLSDNILNAIRNKGFEKPTDIQMKVIPLFLNDEYNIVAQARTGSGKTASFAIPLI 66 Query: 98 QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ 157 + ++ + +A+IL PTRELA+Q+ + +L N++ GG + I+ L Sbjct: 67 ELVN-ENNGIEAIILTPTRELAIQVADEIESLKGNKNLKIAKIYGGKAIYPQIKALKNA- 124 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLI 217 ++V GTPGR+ D I R +L + +K +LDEADEMLN GF + + + +++L Sbjct: 125 NIVVGTPGRILDHINRGTLNLKNVKYFILDEADEMLNMGFIKDVEKILNACNKDKRILLF 184 Query: 218 SATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTI 277 SAT+P EIL + K+M D I K + I+Q +V V E +F+ LC L Sbjct: 185 SATMPREILNLAKKYMGDYSFIKAKINA----NIEQSYVEVNENE-RFEALCRLLKNKEF 239 Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337 ++FC TKR L +R+ F ++HGD+ Q +RE +++ F+ R+LI+TDV Sbjct: 240 Y-GLVFCKTKRDTKELASMLRDIGFKAGAIHGDLSQSQREKVIRLFKQKKIRILIATDVM 298 Query: 338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYS 397 +RG+DV ++ +INY LP N E Y+HRIGR+GR G+KG AI+ + + + LR IE+ Sbjct: 299 SRGIDVNDLNCVINYHLPQNPESYMHRIGRTGRAGKKGKAISIINRREYKKLRYIERAMK 358 Query: 398 TQIDEM 403 +I ++ Sbjct: 359 LKIKKL 364 >5SUQ-A nrPDB Length = 446 Score = 403 bits (1037), Expect = e-113, Method: Composition-based stats. Identities = 136/374 (36%), Positives = 213/374 (56%), Gaps = 8/374 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +L R I GFE PS +QQ I Q I G DV+ Q++SG GKTA F +S LQ Sbjct: 64 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 123 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDY--- 155 LD E +++ RELA QI+ L YM +V+ GGT + +D L Sbjct: 124 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 183 Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQV 214 H+V TPGR+ ++R + + +K V+DE D++L + + +++R P QV Sbjct: 184 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 243 Query: 215 VLISATLPHEILEMTNKFMTDPIRILVKRDE-LTLEGIKQFFVAVEREEWKFDTLCDLYD 273 ++ SATL EI + +F+ +P+ I V + LTL G++Q+++ +E E K L L D Sbjct: 244 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE-EREKNRKLAQLLD 302 Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333 L Q +IF + + + LT+ + +NF ++HG M Q+ER + K F+ R+ +S Sbjct: 303 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 362 Query: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDI 392 TDV+ RG+D+ +++L INYDL N + Y+HR+GR+GR+G KG+AI+FV +D +L I Sbjct: 363 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 422 Query: 393 EQYYSTQIDEMPMN 406 ++ + +I E P Sbjct: 423 QERFDVKIAEFPEE 436 >5SUP-A nrPDB Length = 390 Score = 402 bits (1032), Expect = e-112, Method: Composition-based stats. Identities = 136/374 (36%), Positives = 213/374 (56%), Gaps = 8/374 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +L R I GFE PS +QQ I Q I G DV+ Q++SG GKTA F +S LQ Sbjct: 8 FKDFLLKPELSRAIIDCGFEHPSEVQQHTIPQSIHGTDVLCQAKSGLGKTAVFVLSTLQQ 67 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDY--- 155 LD E +++ RELA QI+ L YM +V+ GGT + +D L Sbjct: 68 LDPVPGEVAVVVICNARELAYQIRNEYLRFSKYMPDVKTAVFYGGTPISKDAELLKNKDT 127 Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQV 214 H+V TPGR+ ++R + + +K V+DE D++L + + +++R P QV Sbjct: 128 APHIVVATPGRLKALVREKYIDLSHVKNFVIDECDKVLEELDMRRDVQEIFRATPRDKQV 187 Query: 215 VLISATLPHEILEMTNKFMTDPIRILVKRDE-LTLEGIKQFFVAVEREEWKFDTLCDLYD 273 ++ SATL EI + +F+ +P+ I V + LTL G++Q+++ +E E K L L D Sbjct: 188 MMFSATLSQEIRPICRRFLQNPLEIFVDDEAKLTLHGLQQYYIKLE-EREKNRKLAQLLD 246 Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333 L Q +IF + + + LT+ + +NF ++HG M Q+ER + K F+ R+ +S Sbjct: 247 DLEFNQVIIFVKSTTRANELTKLLNASNFPAITVHGHMKQEERIARYKAFKDFEKRICVS 306 Query: 334 TDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV-KNDDIRILRDI 392 TDV+ RG+D+ +++L INYDL N + Y+HR+GR+GR+G KG+AI+FV +D +L I Sbjct: 307 TDVFGRGIDIERINLAINYDLTNEADQYLHRVGRAGRFGTKGLAISFVSSKEDEEVLAKI 366 Query: 393 EQYYSTQIDEMPMN 406 ++ + +I E P Sbjct: 367 QERFDVKIAEFPEE 380 >2DB3-A nrPDB Length = 434 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 120/388 (30%), Positives = 202/388 (52%), Gaps = 10/388 (2%) Query: 25 KVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQS 84 V+ S+ F + LR+ ++ + G++ P+ IQ+ +I I GRD++A +Q+ Sbjct: 43 PVKVTGSDVPQPIQHFTSADLRDIIIDNVNKSGYKIPTPIQKCSIPVISSGRDLMACAQT 102 Query: 85 GTGKTATFSISVLQCL-----DIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHA 139 G+GKTA F + +L L ++++ Q +I++PTRELA+QI ++ Sbjct: 103 GSGKTAAFLLPILSKLLEDPHELELGRPQVVIVSPTRELAIQIFNEARKFAFESYLKIGI 162 Query: 140 CIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKE 199 GGT+ + G HVV TPGR+ D + R + + +VLDEAD ML+ GF E Sbjct: 163 VYGGTSFRHQNECITRGCHVVIATPGRLLDFVDRTFITFEDTRFVVLDEADRMLDMGFSE 222 Query: 200 QIYDVYRY--LPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257 + + + + P Q ++ SAT P EI M +F+ + + + + +KQ Sbjct: 223 DMRRIMTHVTMRPEHQTLMFSATFPEEIQRMAGEFLKNYVFVAIGIVGGACSDVKQTIYE 282 Query: 258 VEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERE 317 V + K L ++ ++F TKR D+L + E F +S+HGD Q +RE Sbjct: 283 VNKYA-KRSKLIEILSE-QADGTIVFVETKRGADFLASFLSEKEFPTTSIHGDRLQSQRE 340 Query: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377 +++F++G+ +VLI+T V +RGLD+ + +INYD+P+ + Y+HRIGR+GR G G A Sbjct: 341 QALRDFKNGSMKVLIATSVASRGLDIKNIKHVINYDMPSKIDDYVHRIGRTGRVGNNGRA 400 Query: 378 INFVKND-DIRILRDIEQYYSTQIDEMP 404 +F + D I D+ + +P Sbjct: 401 TSFFDPEKDRAIAADLVKILEGSGQTVP 428 >3PEW-A nrPDB Length = 395 Score = 395 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 149/382 (39%), Positives = 243/382 (63%), Gaps = 15/382 (3%) Query: 36 VTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFS 93 + +FD +GL +LL+GIYA F+KPS IQ+RA+ ++ R++IAQSQSGTGKTA FS Sbjct: 3 MAKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFS 62 Query: 94 ISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKL 153 +++L ++ + QA+ LAP+RELA Q + + +G + + + + E +++ Sbjct: 63 LTMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIV--PDSFEKNKQI 120 Query: 154 DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPAT 212 + V+ GTPG V D++RR+ ++ + IK+ VLDEAD ML++ G +Q V R+LP T Sbjct: 121 N--AQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDT 178 Query: 213 QVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLY 272 Q+VL SAT + + K + + + ++ +E+ ++ IKQ ++ + E KFD L +LY Sbjct: 179 QLVLFSATFADAVRQYAKKIVPNANTLELQTNEVNVDAIKQLYMDCKNEADKFDVLTELY 238 Query: 273 DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332 +TI ++IF TK+ + L K++ VS +HGD+ +ER+ ++ +FR G S+VLI Sbjct: 239 GVMTIGSSIIFVATKKTANVLYGKLKSEGHEVSILHGDLQTQERDRLIDDFREGRSKVLI 298 Query: 333 STDVWARGLDVPQVSLIINYDLPN------NRELYIHRIGRSGRYGRKGVAINFVKN-DD 385 +T+V ARG+D+P VS+++NYDLP + YIHRIGR+GR+GRKGVAI+FV + + Sbjct: 299 TTNVLARGIDIPTVSMVVNYDLPTLANGQADPATYIHRIGRTGRFGRKGVAISFVHDKNS 358 Query: 386 IRILRDIEQYYS-TQIDEMPMN 406 IL I++Y+ ++ +P + Sbjct: 359 FNILSAIQKYFGDIEMTRVPTD 380 >6B4I-E nrPDB Length = 430 Score = 395 bits (1016), Expect = e-110, Method: Composition-based stats. Identities = 142/410 (34%), Positives = 242/410 (59%), Gaps = 18/410 (4%) Query: 12 SARKRLLKEEDMTKVEFETSEEVDV---TPTFDTMGLREDLLRGIYAYGFEKPSAIQQRA 68 + R ++ +VE + +F+ + L+ LL+G+YA GF +PS IQ+ A Sbjct: 14 NKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENA 73 Query: 69 IKQII--KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 + ++ +++IAQSQSGTGKTA F +++L ++ + Q L L+PT ELA+Q K + Sbjct: 74 LPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVI 133 Query: 127 LALGD-YMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKML 184 +G Y ++ + G + R + +V GTPG V D + + + + IK+ Sbjct: 134 EQMGKFYPELKLAYAVRGNKLE---RGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVF 190 Query: 185 VLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR 243 VLDEAD M+ +G ++Q + R LP Q++L SAT + + K + DP I +KR Sbjct: 191 VLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKR 250 Query: 244 DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFT 303 +E TL+ IKQ++V + KF LC+LY +TI QA+IFC+T++ WL ++ + Sbjct: 251 EEETLDTIKQYYVLCSSRDEKFQALCNLYGAITIAQAMIFCHTRKTASWLAAELSKEGHQ 310 Query: 304 VSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLP------NN 357 V+ + G+M ++R ++++ FR G +VL++T+V ARG+DV QVS++IN+DLP + Sbjct: 311 VALLSGEMMVEQRAAVIERFREGKEKVLVTTNVCARGIDVEQVSVVINFDLPVDKDGNPD 370 Query: 358 RELYIHRIGRSGRYGRKGVAINFVK-NDDIRILRDIEQYYSTQIDEMPMN 406 E Y+HRIGR+GR+G++G+A+N V + IL I+++++ +I+ + + Sbjct: 371 NETYLHRIGRTGRFGKRGLAVNMVDSKHSMNILNRIQEHFNKKIERLDTD 420 >6CB1-p nrPDB Length = 505 Score = 390 bits (1001), Expect = e-109, Method: Composition-based stats. Identities = 118/434 (27%), Positives = 219/434 (50%), Gaps = 30/434 (6%) Query: 7 MATSGSARKRLLKEEDMTKV-EFETSEEVDVTP---------TFDTMGLREDLLRGIYAY 56 MAT + R R + + V E TS++ + P F+ + L + L+ I Sbjct: 1 MATPSNKRSRDSESTEEPVVDEKSTSKQNNAAPEGEQTTCVEKFEELKLSQPTLKAIEKM 60 Query: 57 GFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQ----ALIL 112 GF +++Q R I ++ GRDV+ +++G+GKT F I ++ L + + +++ Sbjct: 61 GFTTMTSVQARTIPPLLAGRDVLGAAKTGSGKTLAFLIPAIELLHSLKFKPRNGTGIIVI 120 Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172 PTRELA+QI L ++ + IGG N ++ KL G +++ TPGR+ D ++ Sbjct: 121 TPTRELALQIFGVARELMEFHSQTFGIVIGGANRRQEAEKLMKGVNMLIATPGRLLDHLQ 180 Query: 173 R-RSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPP-ATQVVLISATLPHEILEMTN 230 + + +K L++DEAD +L GF++++ + + LP Q +L SAT ++ ++ Sbjct: 181 NTKGFVFKNLKALIIDEADRILEIGFEDEMRQIIKILPNEDRQSMLFSATQTTKVEDLAR 240 Query: 231 KFMTD-PIRILV--KRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287 + P+ I V + D T +G++Q +V + ++ +F L + ++F ++ Sbjct: 241 ISLRPGPLFINVVPETDNSTADGLEQGYVVCDSDK-RFLLLFSFLKRNQKKKIIVFLSSC 299 Query: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347 V + E + + V +HG Q++R + EF + +LI TDV ARGLD+P V Sbjct: 300 NSVKYYAELLNYIDLPVLELHGKQKQQKRTNTFFEFCNAERGILICTDVAARGLDIPAVD 359 Query: 348 LIINYDLPNNRELYIHRIGRSGRYGR-KGVAINFVKNDDIRILRDIE---------QYYS 397 II +D P++ YIHR+GR+ R + KG ++ F+ +++ LR ++ ++ Sbjct: 360 WIIQFDPPDDPRDYIHRVGRTARGTKGKGKSLMFLTPNELGFLRYLKASKVPLNEYEFPE 419 Query: 398 TQIDEMPMNVADLI 411 +I + + LI Sbjct: 420 NKIANVQSQLEKLI 433 >4KBG-A nrPDB Length = 365 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 123/367 (33%), Positives = 202/367 (55%), Gaps = 8/367 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ ++L ++ G P+ IQ A+ ++G+D+I Q+++GTGKT F++ + + Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 100 LDI---QVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYG 156 L + R+ +AL+L PTRELA+Q+ L A+ + ++ A GGT G+ L G Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASELTAVAPH--LKVVAVYGGTGYGKQKEALLRG 120 Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVL 216 V TPGR D +R+ L +++ VLDEADEML+ GF+E++ + PP+ Q +L Sbjct: 121 ADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLL 180 Query: 217 ISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT 276 SATLP + ++M +P+ I V +DE + V + + L DL + Sbjct: 181 FSATLPSWAKRLAERYMKNPVLINVIKDEPVTYEEEAVPAPVRG---RLEVLSDLLYVAS 237 Query: 277 ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDV 336 +A++F TK + + + + + ++HGD+ Q ERE ++ FR G RVL++TDV Sbjct: 238 PDRAMVFTRTKAETEEIAQGLLRLGHPAQALHGDLSQGERERVLGAFRQGEVRVLVATDV 297 Query: 337 WARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYY 396 ARGLD+PQV L+++Y LP+ E Y HR GR+GR GR G + + R + +E+ Sbjct: 298 AARGLDIPQVDLVVHYRLPDRAEAYQHRSGRTGRAGRGGRVVLLYGPRERRDVEALERAV 357 Query: 397 STQIDEM 403 + + Sbjct: 358 GRRFKRV 364 >3FHO-A nrPDB Length = 508 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 139/354 (39%), Positives = 217/354 (61%), Gaps = 14/354 (3%) Query: 63 AIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 IQ++A+ ++ R++I QSQSGTGKTA F++++L +D V + QA+ LAP+RELA Sbjct: 144 KIQEKALPLLLSNPPRNMIGQSQSGTGKTAAFALTMLSRVDASVPKPQAICLAPSRELAR 203 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 QI + +G Y V+ G + K+D +V GTPG V D+++RR L R Sbjct: 204 QIMDVVTEMGKYTEVKTA--FGIKDSVPKGAKID--AQIVIGTPGTVMDLMKRRQLDARD 259 Query: 181 IKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRI 239 IK+ VLDEAD ML++ G +Q + LP TQ+VL SAT + + +F + I Sbjct: 260 IKVFVLDEADNMLDQQGLGDQSMRIKHLLPRNTQIVLFSATFSERVEKYAERFAPNANEI 319 Query: 240 LVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRE 299 +K +EL++EGIKQ ++ + EE K++ L +LY LTI Q++IFC K + + +M Sbjct: 320 RLKTEELSVEGIKQLYMDCQSEEHKYNVLVELYGLLTIGQSIIFCKKKDTAEEIARRMTA 379 Query: 300 ANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLP---- 355 TV+ + G++ +R++IM FR G S+VL++T+V ARG+DV QV+L++NYD+P Sbjct: 380 DGHTVACLTGNLEGAQRDAIMDSFRVGTSKVLVTTNVIARGIDVSQVNLVVNYDMPLDQA 439 Query: 356 --NNRELYIHRIGRSGRYGRKGVAINFVKN-DDIRILRDIEQYYSTQIDEMPMN 406 + + Y+HRIGR+GR+GR GV+INFV + + I++Y+ I +P + Sbjct: 440 GRPDPQTYLHRIGRTGRFGRVGVSINFVHDKKSWEEMNAIQEYFQRPITRVPTD 493 >5ZWN-y nrPDB Length = 588 Score = 354 bits (908), Expect = 5e-98, Method: Composition-based stats. Identities = 115/396 (29%), Positives = 201/396 (50%), Gaps = 29/396 (7%) Query: 28 FETSEEVDVTPTFDTMGL-REDLLRGIY-AYGFEKPSAIQQRAIKQII---KGRDVIAQS 82 + + ++ + + DLLR I F P+ IQ+ I + + RD + + Sbjct: 162 TKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVA 221 Query: 83 QSGTGKTATFSISVLQCLDIQV---------RETQALILAPTRELAVQIQKGLLALGD-- 131 +G+GKT F I +L + +ALILAPTREL QIQK + Sbjct: 222 STGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIW 281 Query: 132 ----YMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLD 187 + + + +GG ++ E L G ++ TPGR+ D + L + ++ LVLD Sbjct: 282 SKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLD 341 Query: 188 EADEMLNKGFKEQIYDVYRYLPPA------TQVVLISATLPHEILEMTNKFMTDPIRILV 241 EAD+M++ GF++Q+ ++ + Q ++ +AT+ I ++ +M P+ + Sbjct: 342 EADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATI 401 Query: 242 KRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM-REA 300 + + I+Q + +E KF L + +IF N K+ DWL EK +E Sbjct: 402 GVETGSEPLIQQVVEYADNDEDKFKKLKPIVAKY-DPPIIIFINYKQTADWLAEKFQKET 460 Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360 N V+ +HG Q++RE ++ FR+ +++I+T+V ARGLD+P VSL++N+ + + Sbjct: 461 NMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDD 520 Query: 361 YIHRIGRSGRYGRKGVAINFVK-NDDIRILRDIEQY 395 YIHRIGR+GR +G A++FV +D ++R++ +Y Sbjct: 521 YIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKY 556 >4W7S-A nrPDB Length = 463 Score = 352 bits (904), Expect = 1e-97, Method: Composition-based stats. Identities = 115/396 (29%), Positives = 201/396 (50%), Gaps = 29/396 (7%) Query: 28 FETSEEVDVTPTFDTMGL-REDLLRGIY-AYGFEKPSAIQQRAIKQII---KGRDVIAQS 82 + + ++ + + DLLR I F P+ IQ+ I + + RD + + Sbjct: 37 TKGGTVENPLRNWEELNIIPRDLLRVIIQELRFPSPTPIQRITIPNVCNMKQYRDFLGVA 96 Query: 83 QSGTGKTATFSISVLQCLDIQV---------RETQALILAPTRELAVQIQKGLLALGD-- 131 +G+GKT F I +L + +ALILAPTREL QIQK + Sbjct: 97 STGSGKTLAFVIPILIKMSRSPPRPPSLKIIDGPKALILAPTRELVQQIQKETQKVTKIW 156 Query: 132 ----YMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLD 187 + + + +GG ++ E L G ++ TPGR+ D + L + ++ LVLD Sbjct: 157 SKESNYDCKVISIVGGHSLEEISFSLSEGCDILVATPGRLIDSLENHLLVMKQVETLVLD 216 Query: 188 EADEMLNKGFKEQIYDVYRYLPPA------TQVVLISATLPHEILEMTNKFMTDPIRILV 241 EAD+M++ GF++Q+ ++ + Q ++ +AT+ I ++ +M P+ + Sbjct: 217 EADKMIDLGFEDQVTNILTKVDINADSAVNRQTLMFTATMTPVIEKIAAGYMQKPVYATI 276 Query: 242 KRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM-REA 300 + + I+Q + +E KF L + +IF N K+ DWL EK +E Sbjct: 277 GVETGSEPLIQQVVEYADNDEDKFKKLKPIVAKY-DPPIIIFINYKQTADWLAEKFQKET 335 Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNREL 360 N V+ +HG Q++RE ++ FR+ +++I+T+V ARGLD+P VSL++N+ + + Sbjct: 336 NMKVTILHGSKSQEQREHSLQLFRTNKVQIMIATNVAARGLDIPNVSLVVNFQISKKMDD 395 Query: 361 YIHRIGRSGRYGRKGVAINFVK-NDDIRILRDIEQY 395 YIHRIGR+GR +G A++FV +D ++R++ +Y Sbjct: 396 YIHRIGRTGRAANEGTAVSFVSAAEDESLIRELYKY 431 >4LJY-A nrPDB Length = 493 Score = 348 bits (892), Expect = 3e-96, Method: Composition-based stats. Identities = 120/441 (27%), Positives = 216/441 (48%), Gaps = 37/441 (8%) Query: 3 TTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGI-YAYGFEKP 61 T ++M+ RL + ++ + + + +GL D + I F Sbjct: 19 TVSSMSEMEVEELRLS----LDNIKIKGTGCPKPVTKWSQLGLSTDTMVLITEKLHFGSL 74 Query: 62 SAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVR------ETQALILAPT 115 + IQ +A+ I+ GRDVI S++G+GKT ++ + +L+ + Q LILAPT Sbjct: 75 TPIQSQALPAIMSGRDVIGISKTGSGKTISYLLPLLRQVKAQRPLSKHETGPMGLILAPT 134 Query: 116 RELAVQIQKGLLALGDY-MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR-- 172 RELA+QI + + + +++ C GG+ + + I L G +V TPGR D++ Sbjct: 135 RELALQIHEEVTKFTEADTSIRSVCCTGGSEMKKQITDLKRGTEIVVATPGRFIDILTLN 194 Query: 173 -RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNK 231 + L T+ I +V+DEAD + + GF+ QI + + + P Q VL SAT P+++ + Sbjct: 195 DGKLLSTKRITFVVMDEADRLFDLGFEPQITQIMKTVRPDKQCVLFSATFPNKLRSFAVR 254 Query: 232 FMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDL-------YDTLT-------- 276 + PI I + + E +KQ F E+ KFD L L +D + Sbjct: 255 VLHSPISITINSKGMVNENVKQKFRICHSEDEKFDNLVQLIHERSEFFDEVQSENDGQSS 314 Query: 277 -----ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVL 331 +A+IF +++ D++++K+ A ++H P +ER +++F+ + +L Sbjct: 315 DVEEVDAKAIIFVSSQNICDFISKKLLNAGIVTCAIHAGKPYQERLMNLEKFKREKNSIL 374 Query: 332 ISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRD 391 + T+V +RGL+VP+VSL+I Y+ Y+H GR+ R R G AI + +D++ Sbjct: 375 LCTEVLSRGLNVPEVSLVIIYNAVKTFAQYVHTTGRTARGSRSGTAITLLLHDELSGAYI 434 Query: 392 IEQYY-STQIDEM-PMNVADL 410 + + +I + P+ +L Sbjct: 435 LSKAMRDEEIKALDPLQAKEL 455 >2Z0M-A nrPDB Length = 337 Score = 337 bits (865), Expect = 4e-93, Method: Composition-based stats. Identities = 103/341 (30%), Positives = 177/341 (51%), Gaps = 19/341 (5%) Query: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104 + E + + I GF+ + +Q + I +++G++V+ ++++G+GKTA ++I +L+ Sbjct: 1 MNEKIEQAIREMGFKNFTEVQSKTIPLMLQGKNVVVRAKTGSGKTAAYAIPILEL----- 55 Query: 105 RETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTP 164 ++L++ PTREL Q+ + +G YM+ + GG I ++ +V TP Sbjct: 56 -GMKSLVVTPTRELTRQVASHIRDIGRYMDTKVAEVYGGMPYKAQINRVRNA-DIVVATP 113 Query: 165 GRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHE 224 GR+ D+ + + + +++++DEAD M GF + I + L SAT+P E Sbjct: 114 GRLLDLWSKGVIDLSSFEIVIIDEADLMFEMGFIDDIKIILAQTSNRKITGLFSATIPEE 173 Query: 225 ILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVERE-EWKFDTLCDLYDTLTITQAVIF 283 I ++ F+T+ I + L ++ FV V+ + K L + D ++F Sbjct: 174 IRKVVKDFITNYEEIE---ACIGLANVEHKFVHVKDDWRSKVQALRENKDKG----VIVF 226 Query: 284 CNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDV 343 T+ +V L + GD+PQ R + FR G +LI+TDV +RGLD+ Sbjct: 227 VRTRNRVAKLVRLFDN----AIELRGDLPQSVRNRNIDAFREGEYDMLITTDVASRGLDI 282 Query: 344 PQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKND 384 P V +IN+D P + YIHRIGR+GR GRKG AI F+ N+ Sbjct: 283 PLVEKVINFDAPQDLRTYIHRIGRTGRMGRKGEAITFILNE 323 >3SQW-A nrPDB Length = 579 Score = 319 bits (818), Expect = 1e-87, Method: Composition-based stats. Identities = 114/415 (27%), Positives = 205/415 (49%), Gaps = 43/415 (10%) Query: 25 KVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII--KGRDVIAQS 82 + + S+EV + + L +++ + I F + +QQ+ IK I+ + DVIA++ Sbjct: 8 VPKEDNSKEVTLDSLLEEGVLDKEIHKAITRMEFPGLTPVQQKTIKPILSSEDHDVIARA 67 Query: 83 QSGTGKTATFSISVLQCLDIQVRETQ----ALILAPTRELAVQIQKGLLALGD----YMN 134 ++GTGKT F I + Q L ++Q A+I+APTR+LA+QI+ + + D Sbjct: 68 KTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVIVAPTRDLALQIEAEVKKIHDMNYGLKK 127 Query: 135 VQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRT-RAIKMLVLDEADEM 192 C + +GGT+ + K++ ++V TPGR+ D++ + S + R + VLDEAD + Sbjct: 128 YACVSLVGGTDFRAAMNKMNKLRPNIVIATPGRLIDVLEKYSNKFFRFVDYKVLDEADRL 187 Query: 193 LNKGFKEQIYDVYRYLPP-------ATQVVLISATLPHEILEMTNKFMTDPIRILV---- 241 L GF++ + + L + +L SATL ++ ++ N M + + Sbjct: 188 LEIGFRDDLETISGILNEKNSKSADNIKTLLFSATLDDKVQKLANNIMNKKECLFLDTVD 247 Query: 242 KRDELTLEGIKQ-----------FFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKV 290 K + E I Q F AVE + + Y +A+IF T + Sbjct: 248 KNEPEAHERIDQSVVISEKFANSIFAAVEHIKKQIKERDSNY------KAIIFAPTVKFT 301 Query: 291 DWLTEKMRE---ANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVS 347 +L ++ + + HG + Q +R S++K F+ S +L+ TDV ARG+D P V Sbjct: 302 SFLCSILKNEFKKDLPILEFHGKITQNKRTSLVKRFKKDESGILVCTDVGARGMDFPNVH 361 Query: 348 LIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDE 402 ++ +P+ YIHRIGR+ R G++G ++ F+ D++ +R++E + I + Sbjct: 362 EVLQIGVPSELANYIHRIGRTARSGKEGSSVLFICKDELPFVRELEDAKNIVIAK 416 >3I62-A nrPDB Length = 563 Score = 316 bits (810), Expect = 1e-86, Method: Composition-based stats. Identities = 120/442 (27%), Positives = 213/442 (48%), Gaps = 57/442 (12%) Query: 12 SARKRLLKEEDMTKVEFE--------------TSEEVDVTPTFDTMGLREDLLRGIYAYG 57 ++R R ED +V F+ S+EV + + L +++ + I Sbjct: 32 NSRPRTRSREDDDEVHFDKTTFSKLIHVPKEDNSKEVTLDSLLEEGVLDKEIHKAITRME 91 Query: 58 FEKPSAIQQRAIKQII--KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQ----ALI 111 F + +QQ+ IK I+ + DVIA++++GTGKT F I + Q L ++Q A+I Sbjct: 92 FPGLTPVQQKTIKPILSSEDHDVIARAKTGTGKTFAFLIPIFQHLINTKFDSQYMVKAVI 151 Query: 112 LAPTRELAVQIQKGLLALGD----YMNVQCHACIGGTNVGEDIRKLDY-GQHVVAGTPGR 166 +APTR+LA+QI+ + + D C + +GGT+ + K++ ++V TPGR Sbjct: 152 VAPTRDLALQIEAEVKKIHDMNYGLKKYACVSLVGGTDFRAAMNKMNKLRPNIVIATPGR 211 Query: 167 VFDMIRRRSLRT-RAIKMLVLDEADEMLNKGFKEQIYDVYRYLPP-------ATQVVLIS 218 + D++ + S + R + VLDEAD +L GF++ + + L + +L S Sbjct: 212 LIDVLEKYSNKFFRFVDYKVLDEADRLLEIGFRDDLETISGILNEKNSKSADNIKTLLFS 271 Query: 219 ATLPHEILEMTNKFMTDPIRILV----KRDELTLEGIKQ-----------FFVAVEREEW 263 ATL ++ ++ N M + + K + E I Q F AVE + Sbjct: 272 ATLDDKVQKLANNIMNKKECLFLDTVDKNEPEAHERIDQSVVISEKFANSIFAAVEHIKK 331 Query: 264 KFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRE---ANFTVSSMHGDMPQKERESIM 320 + Y +A+IF T + +L ++ + + HG + Q +R S++ Sbjct: 332 QIKERDSNY------KAIIFAPTVKFTSFLCSILKNEFKKDLPILEFHGKITQNKRTSLV 385 Query: 321 KEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 380 K F+ S +L+ TDV ARG+D P V ++ +P+ YIHRIGR+ R G++G ++ F Sbjct: 386 KRFKKDESGILVCTDVGARGMDFPNVHEVLQIGVPSELANYIHRIGRTARSGKEGSSVLF 445 Query: 381 VKNDDIRILRDIEQYYSTQIDE 402 + D++ +R++E + I + Sbjct: 446 ICKDELPFVRELEDAKNIVIAK 467 >5ZBZ-A nrPDB Length = 220 Score = 288 bits (738), Expect = 2e-78, Method: Composition-based stats. Identities = 139/220 (63%), Positives = 172/220 (78%), Gaps = 1/220 (0%) Query: 25 KVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQS 84 S ++ +FD M L E LLRGIYAYGFEKPSAIQQRAI IKG DVIAQ+QS Sbjct: 1 GEGVIESNWNEIVDSFDDMNLSESLLRGIYAYGFEKPSAIQQRAILPCIKGYDVIAQAQS 60 Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 GTGKTATF+IS+LQ +++ ++ TQAL+LAPTRELA QIQK ++ALGDYM CHACIGGT Sbjct: 61 GTGKTATFAISILQQIELDLKATQALVLAPTRELAQQIQKVVMALGDYMGASCHACIGGT 120 Query: 145 NVGEDIRKLDY-GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYD 203 NV +++KL H++ GTPGRVFDM+ RR L + IKM VLDEADEML++GFK+QIYD Sbjct: 121 NVRAEVQKLQMEAPHIIVGTPGRVFDMLNRRYLSPKYIKMFVLDEADEMLSRGFKDQIYD 180 Query: 204 VYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR 243 +++ L TQVVL+SAT+P ++LE+T KFM DPIRILVK+ Sbjct: 181 IFQKLNSNTQVVLLSATMPSDVLEVTKKFMRDPIRILVKK 220 >3BOR-A nrPDB Length = 237 Score = 288 bits (737), Expect = 3e-78, Method: Composition-based stats. Identities = 142/219 (64%), Positives = 174/219 (79%), Gaps = 1/219 (0%) Query: 27 EFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGT 86 S ++ FD M L+E LLRGIYAYGFEKPSAIQQRAI IKG DVIAQ+QSGT Sbjct: 19 GVIESNWNEIVDNFDDMNLKESLLRGIYAYGFEKPSAIQQRAIIPCIKGYDVIAQAQSGT 78 Query: 87 GKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNV 146 GKTATF+IS+LQ L+I+ +ETQAL+LAPTRELA QIQK +LALGDYM CHACIGGTNV Sbjct: 79 GKTATFAISILQQLEIEFKETQALVLAPTRELAQQIQKVILALGDYMGATCHACIGGTNV 138 Query: 147 GEDIRKLD-YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVY 205 +++KL H+V GTPGRVFDM+ RR L + IKM VLDEADEML++GFK+QIY+++ Sbjct: 139 RNEMQKLQAEAPHIVVGTPGRVFDMLNRRYLSPKWIKMFVLDEADEMLSRGFKDQIYEIF 198 Query: 206 RYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRD 244 + L + QVVL+SAT+P ++LE+T KFM DPIRILVK++ Sbjct: 199 QKLNTSIQVVLLSATMPTDVLEVTKKFMRDPIRILVKKE 237 >6CRM-A nrPDB Length = 541 Score = 275 bits (704), Expect = 2e-74, Method: Composition-based stats. Identities = 75/359 (20%), Positives = 153/359 (42%), Gaps = 32/359 (8%) Query: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQV 104 L + +L+ +G+++ Q I +++GRD + +G GK+ + I L V Sbjct: 32 LAKQVLQ--ETFGYQQFRPGQATIIDAVLEGRDCLVVMPTGGGKSLCYQIPAL------V 83 Query: 105 RETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH-----V 159 + ++++P L LLA N AC+ T E+ + + G + Sbjct: 84 KTGLTIVVSPLISLMKDQVDQLLA-----NGVAAACLNSTQSREEQQAVLAGCRTGQVRL 138 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQIYDV--YRYLPPATQVV 215 + P R+ +L + M+ +DEA + G F+ + + R PA + Sbjct: 139 LYIAPERLMMDNFIDTLGYWDLAMVAVDEAHCISQWGHDFRPEYAALGQLRARFPAVPFM 198 Query: 216 LISATLPHEILEMTNKFM--TDPIRILVKRDELTLEGIKQFFVAVEREEWK-FDTLCDLY 272 ++AT + + DP L++ I+ + E++K D L Sbjct: 199 ALTATADDTTRRDIVRLLGLDDP---LIEISSFDRPNIRYMLM----EKFKPLDQLMRYV 251 Query: 273 DTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLI 332 +I+CN++ KV+ +++ + ++ H + + R S+ ++F+ ++++ Sbjct: 252 QEQRGKSGIIYCNSRAKVEDTAARLQSRGISAAAYHAGLEHEVRASVQEKFQRDDLQIVV 311 Query: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRD 391 +T + G++ P V ++++D+P N E Y GR+GR G A+ F D+ LR Sbjct: 312 ATVAFGMGINKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLRR 370 >4CDG-A nrPDB Length = 673 Score = 270 bits (690), Expect = 8e-73, Method: Composition-based stats. Identities = 71/378 (18%), Positives = 151/378 (39%), Gaps = 42/378 (11%) Query: 40 FDTMGLR--EDLLRGIYA-YGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISV 96 F ++ +++++ + +G Q AI + G D +G GK+ + + Sbjct: 11 FQSLSFPHTKEMMKIFHKKFGLHNFRTNQLEAINAALLGEDCFILMPTGGGKSLCYQLPA 70 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIG------GTNVGEDI 150 C+ V ++++P R L V + L +L ++ G TN+ + Sbjct: 71 --CVSPGV----TVVISPLRSLIVDQVQKLTSL----DIPATYLTGDKTDSEATNIYLQL 120 Query: 151 RKLDYGQHVVAGTPGRV---------FDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKE 199 K D ++ TP ++ + + R L R V+DEA + G F++ Sbjct: 121 SKKDPIIKLLYVTPEKICASNRLISTLENLYERKLLAR----FVIDEAHCVSQWGHDFRQ 176 Query: 200 QIYDV--YRYLPPATQVVLISATLPHEILE--MTNKFMTDPIRILVKRDELTLEGIKQFF 255 + R P+ V+ ++AT + + +T + P V +K + Sbjct: 177 DYKRMNMLRQKFPSVPVMALTATANPRVQKDILTQLKILRP---QVFSMSFNRHNLKYYV 233 Query: 256 VAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKE 315 + + ++ FD L + +I+C ++R+ D + + ++ + H + Sbjct: 234 LPKKPKKVAFDCLEWIRKHHPYDSGIIYCLSRRECDTMADTLQRDGLAALAYHAGLSDSA 293 Query: 316 RESIMKEF-RSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRK 374 R+ + +++ +V+ +T + G+D P V +I+ LP + E Y GR+GR G Sbjct: 294 RDEVQQKWINQDGCQVICATIAFGMGIDKPDVRFVIHASLPKSVEGYYQESGRAGRDGEI 353 Query: 375 GVAINFVKNDDIRILRDI 392 + F D+ L+ + Sbjct: 354 SHCLLFYTYHDVTRLKRL 371 >1WRB-A nrPDB Length = 253 Score = 264 bits (676), Expect = 3e-71, Method: Composition-based stats. Identities = 78/252 (30%), Positives = 125/252 (49%), Gaps = 16/252 (6%) Query: 15 KRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIK 74 K +T ++ + +V FD + L + I +++P+ IQ+ AI I++ Sbjct: 3 KYDSIPVSVTGPDYSAT---NVIENFDELKLDPTIRNNILLASYQRPTPIQKNAIPAILE 59 Query: 75 GRDVIAQSQSGTGKTATFSISVLQCLD---------IQVRETQALILAPTRELAVQIQKG 125 RD++A +Q+G+GKTA F I ++ L + + LILAPTRELA+QI Sbjct: 60 HRDIMACAQTGSGKTAAFLIPIINHLVCQDLNQQRYSKTAYPKCLILAPTRELAIQILSE 119 Query: 126 LLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLV 185 ++ GG + IR++ G H++ TPGR+ D I + + K +V Sbjct: 120 SQKFSLNTPLRSCVVYGGADTHSQIREVQMGCHLLVATPGRLVDFIEKNKISLEFCKYIV 179 Query: 186 LDEADEMLNKGFKEQIYDVY--RYLPP--ATQVVLISATLPHEILEMTNKFMTDPIRILV 241 LDEAD ML+ GF+ QI + +P Q ++ SAT P EI ++ F+ + I + V Sbjct: 180 LDEADRMLDMGFEPQIRKIIEESNMPSGINRQTLMFSATFPKEIQKLAADFLYNYIFMTV 239 Query: 242 KRDELTLEGIKQ 253 R T + IKQ Sbjct: 240 GRVGSTSDSIKQ 251 >1OYY-A nrPDB Length = 523 Score = 261 bits (666), Expect = 6e-70, Method: Composition-based stats. Identities = 69/350 (19%), Positives = 141/350 (40%), Gaps = 30/350 (8%) Query: 54 YAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILA 113 +G+++ Q+ I ++ GRD + +G GK+ + I L + ++++ Sbjct: 19 ETFGYQQFRPGQEEIIDTVLSGRDCLVVMPTGGGKSLCYQIPAL------LLNGLTVVVS 72 Query: 114 PTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH-----VVAGTPGRVF 168 P L L A N AC+ T E ++ G ++ P R+ Sbjct: 73 PLISLMKDQVDQLQA-----NGVAAACLNSTQTREQQLEVMTGCRTGQIRLLYIAPERLM 127 Query: 169 DMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQIYDV--YRYLPPATQVVLISATLPHE 224 L +L +DEA + G F+ + + R P + ++AT Sbjct: 128 LDNFLEHLAHWNPVLLAVDEAHCISQWGHDFRPEYAALGQLRQRFPTLPFMALTATADDT 187 Query: 225 ILEMTNKFM--TDPIRILVKRDELTLEGIKQFFVAVEREEWK-FDTLCDLYDTLTITQAV 281 + + + DP L++ I+ + E++K D L + Sbjct: 188 TRQDIVRLLGLNDP---LIQISSFDRPNIRYMLM----EKFKPLDQLMRYVQEQRGKSGI 240 Query: 282 IFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGL 341 I+CN++ KV+ +++ + ++ H + R + ++F+ +++++T + G+ Sbjct: 241 IYCNSRAKVEDTAARLQSKGISAAAYHAGLENNVRADVQEKFQRDDLQIVVATVAFGMGI 300 Query: 342 DVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRD 391 + P V ++++D+P N E Y GR+GR G A+ F D+ LR Sbjct: 301 NKPNVRFVVHFDIPRNIESYYQETGRAGRDGLPAEAMLFYDPADMAWLRR 350 >5GJU-A nrPDB Length = 205 Score = 261 bits (666), Expect = 6e-70, Method: Composition-based stats. Identities = 83/204 (40%), Positives = 120/204 (58%), Gaps = 1/204 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 TF +GL+ +L + G+EKPS IQ I ++ GRDV+ +Q+G+GKTA FS+ +LQ Sbjct: 2 TFADLGLKAPILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQ 61 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQ 157 LD +++ Q L+LAPTRELAVQ+ + + +M V A GG +R L G Sbjct: 62 NLDPELKAPQILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGP 121 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLI 217 +V GTPGR+ D ++R +L + LVLDEADEML GF E + + +P Q L Sbjct: 122 QIVVGTPGRLLDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPEGHQTALF 181 Query: 218 SATLPHEILEMTNKFMTDPIRILV 241 SAT+P I +T +FM +P + + Sbjct: 182 SATMPEAIRRITRRFMKEPQEVRI 205 >1QVA-A nrPDB Length = 223 Score = 260 bits (664), Expect = 9e-70, Method: Composition-based stats. Identities = 132/224 (58%), Positives = 167/224 (74%), Gaps = 3/224 (1%) Query: 20 EEDMTKVEFET--SEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRD 77 E +T +E + V FD M L E LLRG++ YGFE+PSAIQQRAI II+G D Sbjct: 1 SEGITDIEESQIQTNYQKVVYKFDDMELDEQLLRGVFGYGFEEPSAIQQRAIMPIIEGHD 60 Query: 78 VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQC 137 V+AQ+QSGTGKT TFSI+ LQ +D V+ QAL+LAPTRELA+QIQK ++AL +M+++ Sbjct: 61 VLAQAQSGTGKTGTFSIAALQRIDTSVKAPQALMLAPTRELALQIQKVVMALAFHMDIKV 120 Query: 138 HACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGF 197 HACIGGT+ ED L Q +V GTPGRVFD I+RR RT IKM +LDEADEML+ GF Sbjct: 121 HACIGGTSFVEDAEGLRDAQ-IVVGTPGRVFDNIQRRRFRTDKIKMFILDEADEMLSSGF 179 Query: 198 KEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILV 241 KEQIY ++ LPP TQVVL+SAT+P+++LE+T KFM +P+RILV Sbjct: 180 KEQIYQIFTLLPPTTQVVLLSATMPNDVLEVTTKFMRNPVRILV 223 >4PX9-A nrPDB Length = 292 Score = 253 bits (647), Expect = 1e-67, Method: Composition-based stats. Identities = 78/266 (29%), Positives = 128/266 (48%), Gaps = 32/266 (12%) Query: 10 SGSARKRLLKEEDMTKVEFETSEEVDV----------TPTFDTMGLREDLLRGIYAYGFE 59 ++ L T + FE +++ V +F + + E ++ I + Sbjct: 27 PSERLEQELFSGGNTGINFEKYDDIPVEATGNNCPPHIESFSDVEMGEIIMGNIELTRYT 86 Query: 60 KPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL------------------D 101 +P+ +Q+ AI I + RD++A +Q+G+GKTA F + +L + Sbjct: 87 RPTPVQKHAIPIIKEKRDLMACAQTGSGKTAAFLLPILSQIYSDGPGEALRAMKENGRYG 146 Query: 102 IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161 + + +L+LAPTRELAVQI + V+ GG ++G+ IR L+ G H++ Sbjct: 147 RRKQYPISLVLAPTRELAVQIYEEARKFSYRSRVRPCVVYGGADIGQQIRDLERGCHLLV 206 Query: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRY--LPPA--TQVVLI 217 TPGR+ DM+ R + K LVLDEAD ML+ GF+ QI + +PP ++ Sbjct: 207 ATPGRLVDMMERGKIGLDFCKYLVLDEADRMLDMGFEPQIRRIVEQDTMPPKGVRHTMMF 266 Query: 218 SATLPHEILEMTNKFMTDPIRILVKR 243 SAT P EI + F+ + I + V R Sbjct: 267 SATFPKEIQMLARDFLDEYIFLAVGR 292 >2GXQ-A nrPDB Length = 207 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 72/205 (35%), Positives = 118/205 (57%), Gaps = 5/205 (2%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ ++L ++ G P+ IQ A+ ++G+D+I Q+++GTGKT F++ + + Sbjct: 3 FKDFPLKPEILEALHGRGLTTPTPIQAAALPLALEGKDLIGQARTGTGKTLAFALPIAER 62 Query: 100 LDI---QVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYG 156 L + R+ +AL+L PTRELA+Q+ L A+ + ++ A GGT G+ L G Sbjct: 63 LAPSQERGRKPRALVLTPTRELALQVASELTAVAPH--LKVVAVYGGTGYGKQKEALLRG 120 Query: 157 QHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVL 216 V TPGR D +R+ L +++ VLDEADEML+ GF+E++ + PP+ Q +L Sbjct: 121 ADAVVATPGRALDYLRQGVLDLSRVEVAVLDEADEMLSMGFEEEVEALLSATPPSRQTLL 180 Query: 217 ISATLPHEILEMTNKFMTDPIRILV 241 SATLP + ++M +P+ I V Sbjct: 181 FSATLPSWAKRLAERYMKNPVLINV 205 >1T6N-A nrPDB Length = 220 Score = 251 bits (642), Expect = 3e-67, Method: Composition-based stats. Identities = 81/205 (39%), Positives = 114/205 (55%), Gaps = 3/205 (1%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F L+ +LLR I GFE PS +Q I Q I G DV+ Q++SG GKTA F ++ LQ Sbjct: 16 FRDFLLKPELLRAIVDCGFEHPSEVQHECIPQAILGMDVLCQAKSGMGKTAVFVLATLQQ 75 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQ- 157 L+ + L++ TRELA QI K YM NV+ GG ++ +D L Sbjct: 76 LEPVTGQVSVLVMCHTRELAFQISKEYERFSKYMPNVKVAVFFGGLSIKKDEEVLKKNCP 135 Query: 158 HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK-GFKEQIYDVYRYLPPATQVVL 216 H+V GTPGR+ + R +SL + IK +LDE D+ML + + + +++R P QV++ Sbjct: 136 HIVVGTPGRILALARNKSLNLKHIKHFILDECDKMLEQLDMRRDVQEIFRMTPHEKQVMM 195 Query: 217 ISATLPHEILEMTNKFMTDPIRILV 241 SATL EI + KFM DP+ I V Sbjct: 196 FSATLSKEIRPVCRKFMQDPMEIFV 220 >1VEC-A nrPDB Length = 206 Score = 251 bits (640), Expect = 5e-67, Method: Composition-based stats. Identities = 75/202 (37%), Positives = 128/202 (63%), Gaps = 1/202 (0%) Query: 40 FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQC 99 F+ L+ +LL GI+ G+EKPS IQ+ +I + GRD++A++++GTGK+ + I +L+ Sbjct: 5 FEDYCLKRELLMGIFEMGWEKPSPIQEESIPIALSGRDILARAKNGTGKSGAYLIPLLER 64 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQCHACIGGTNVGEDIRKLDYGQH 158 LD++ QA+++ PTRELA+Q+ + + + +M + A GGTN+ +DI +LD H Sbjct: 65 LDLKKDNIQAMVIVPTRELALQVSQICIQVSKHMGGAKVMATTGGTNLRDDIMRLDDTVH 124 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLIS 218 VV TPGR+ D+I++ + ++M+VLDEAD++L++ F + + D+ LP Q++L S Sbjct: 125 VVIATPGRILDLIKKGVAKVDHVQMIVLDEADKLLSQDFVQIMEDIILTLPKNRQILLYS 184 Query: 219 ATLPHEILEMTNKFMTDPIRIL 240 AT P + + N + P I Sbjct: 185 ATFPLSVQKFMNSHLEKPYEIN 206 >3FE2-A nrPDB Length = 242 Score = 247 bits (632), Expect = 5e-66, Method: Composition-based stats. Identities = 65/226 (28%), Positives = 104/226 (46%), Gaps = 5/226 (2%) Query: 26 VEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSG 85 + F +++ I F +P+AIQ + + G D++ +Q+G Sbjct: 17 ITVRGHNCPKPVLNFYEANFPANVMDVIARQNFTEPTAIQAQGWPVALSGLDMVGVAQTG 76 Query: 86 TGKTATFSISVLQCLDIQV-----RETQALILAPTRELAVQIQKGLLALGDYMNVQCHAC 140 +GKT ++ + + ++ Q L+LAPTRELA Q+Q+ ++ Sbjct: 77 SGKTLSYLLPAIVHINHQPFLERGDGPICLVLAPTRELAQQVQQVAAEYCRACRLKSTCI 136 Query: 141 IGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQ 200 GG G IR L+ G + TPGR+ D + R LVLDEAD ML+ GF+ Q Sbjct: 137 YGGAPKGPQIRDLERGVEICIATPGRLIDFLECGKTNLRRTTYLVLDEADRMLDMGFEPQ 196 Query: 201 IYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDEL 246 I + + P Q ++ SAT P E+ ++ F+ D I I + EL Sbjct: 197 IRKIVDQIRPDRQTLMWSATWPKEVRQLAEDFLKDYIHINIGALEL 242 >5H1Y-A nrPDB Length = 281 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 72/240 (30%), Positives = 116/240 (48%), Gaps = 14/240 (5%) Query: 28 FETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTG 87 E +F M +LRG+ G P+ IQ + I I+ GRD+I + +G+G Sbjct: 42 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 101 Query: 88 KTATFSISVLQ-CLDIQVR-------ETQALILAPTRELAVQIQK------GLLALGDYM 133 KT F++ V+ CL+ + R LI+ P+RELA Q LL Sbjct: 102 KTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSP 161 Query: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193 ++C CIGG +V E + + +G H++ TPGR+ D+++++ + + L LDEAD M+ Sbjct: 162 LLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMI 221 Query: 194 NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQ 253 + GF+ I ++ Y Q +L SAT+P +I + P+ I V R + Q Sbjct: 222 DMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVGRAGAASLDVIQ 281 >3BER-A nrPDB Length = 249 Score = 242 bits (619), Expect = 2e-64, Method: Composition-based stats. Identities = 70/227 (30%), Positives = 120/227 (52%), Gaps = 1/227 (0%) Query: 16 RLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG 75 + ++E D + E + T TF +G+ + L G+ KP+ IQ AI ++G Sbjct: 21 QSMEEHDSPTEASQPIVEEEETKTFKDLGVTDVLCEACDQLGWTKPTKIQIEAIPLALQG 80 Query: 76 RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 RD+I +++G+GKT F++ +L L + AL+L PTRELA QI + ALG + V Sbjct: 81 RDIIGLAETGSGKTGAFALPILNALLETPQRLFALVLTPTRELAFQISEQFEALGSSIGV 140 Query: 136 QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEMLN 194 Q +GG + L H++ TPGR+ D + + RA+K LV+DEAD +LN Sbjct: 141 QSAVIVGGIDSMSQSLALAKKPHIIIATPGRLIDHLENTKGFNLRALKYLVMDEADRILN 200 Query: 195 KGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILV 241 F+ ++ + + +P + L SAT+ ++ ++ + +P++ V Sbjct: 201 MDFETEVDKILKVIPRDRKTFLFSATMTKKVQKLQRAALKNPVKCAV 247 >6AIC-A nrPDB Length = 214 Score = 240 bits (613), Expect = 8e-64, Method: Composition-based stats. Identities = 75/203 (36%), Positives = 120/203 (59%), Gaps = 2/203 (0%) Query: 39 TFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQ 98 F +G+ ++ ++ + + GF++P+ IQ+ +I ++G D++ Q+Q+GTGKT F I +++ Sbjct: 3 NFKELGISDNTVQSLESMGFKEPTPIQKDSIPYALQGIDILGQAQTGTGKTGAFGIPLIE 62 Query: 99 CLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158 + + + Q+LILAPTRELA+Q+ + L VQ GG + I+ L G Sbjct: 63 KV-VGKQGVQSLILAPTRELAMQVAEQLREFSRGQGVQVVTVFGGMPIERQIKALKKGPQ 121 Query: 159 VVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPP-ATQVVLI 217 +V GTPGRV D + RR+L+T I L+LDEADEM+N GF + + + +P Q +L Sbjct: 122 IVVGTPGRVIDHLNRRTLKTDGIHTLILDEADEMMNMGFIDDMRFIMDKIPAVQRQTMLF 181 Query: 218 SATLPHEILEMTNKFMTDPIRIL 240 SAT+P I + +FM P I Sbjct: 182 SATMPKAIQALVQQFMKSPKIIK 204 >5GVS-A nrPDB Length = 231 Score = 238 bits (608), Expect = 3e-63, Method: Composition-based stats. Identities = 70/229 (30%), Positives = 113/229 (49%), Gaps = 14/229 (6%) Query: 28 FETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTG 87 E +F M +LRG+ G P+ IQ + I I+ GRD+I + +G+G Sbjct: 3 VEGDGIPPPIKSFKEMKFPAAILRGLKKKGIHHPTPIQIQGIPTILSGRDMIGIAFTGSG 62 Query: 88 KTATFSISVLQ-CLDIQVR-------ETQALILAPTRELAVQIQK------GLLALGDYM 133 KT F++ V+ CL+ + R LI+ P+RELA Q LL Sbjct: 63 KTLVFTLPVIMFCLEQEKRLPFSKREGPYGLIICPSRELARQTHGILEYYCRLLQEDSSP 122 Query: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193 ++C CIGG +V E + + +G H++ TPGR+ D+++++ + + L LDEAD M+ Sbjct: 123 LLRCALCIGGMSVKEQMETIRHGVHMMVATPGRLMDLLQKKMVSLDICRYLALDEADRMI 182 Query: 194 NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVK 242 + GF+ I ++ Y Q +L SAT+P +I + P+ I V Sbjct: 183 DMGFEGDIRTIFSYFKGQRQTLLFSATMPKKIQNFAKSALVKPVTINVG 231 >3IUY-A nrPDB Length = 228 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 68/215 (31%), Positives = 106/215 (49%), Gaps = 8/215 (3%) Query: 34 VDVTPTFDT-MGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATF 92 T F DLL+ I G KP+ IQ +A I++G D+I +Q+GTGKT ++ Sbjct: 15 PKPTCRFKDAFQQYPDLLKSIIRVGILKPTPIQSQAWPIILQGIDLIVVAQTGTGKTLSY 74 Query: 93 SISVLQCLDIQV------RETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNV 146 + LD Q L+L PTRELA+ ++ Y ++ GG N Sbjct: 75 LMPGFIHLDSQPISREQRNGPGMLVLTPTRELALHVEAECSKYS-YKGLKSICIYGGRNR 133 Query: 147 GEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYR 206 I + G ++ TPGR+ D+ S+ R+I LV+DEAD+ML+ F+ QI + Sbjct: 134 NGQIEDISKGVDIIIATPGRLNDLQMNNSVNLRSITYLVIDEADKMLDMEFEPQIRKILL 193 Query: 207 YLPPATQVVLISATLPHEILEMTNKFMTDPIRILV 241 + P Q V+ SAT P + ++ ++ DP+ + V Sbjct: 194 DVRPDRQTVMTSATWPDTVRQLALSYLKDPMIVYV 228 >2OXC-A nrPDB Length = 230 Score = 231 bits (589), Expect = 5e-61, Method: Composition-based stats. Identities = 86/227 (37%), Positives = 133/227 (58%), Gaps = 4/227 (1%) Query: 20 EEDMTKVEFETSEEVDVTPT-FDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDV 78 +D++ T + + P F+++ L +L G+ A GFE+PS +Q +AI G D+ Sbjct: 5 AQDLSSPRTRTGDVLLAEPADFESLLLSRPVLEGLRAAGFERPSPVQLKAIPLGRCGLDL 64 Query: 79 IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYM-NVQC 137 I Q++SGTGKT FS L L ++ TQ LILAPTRE+AVQI + A+G M ++C Sbjct: 65 IVQAKSGTGKTCVFSTIALDSLVLENLSTQILILAPTREIAVQIHSVITAIGIKMEGLEC 124 Query: 138 HACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG- 196 H IGGT + +D +L H+ G+PGR+ +I L +I++ +LDEAD++L +G Sbjct: 125 HVFIGGTPLSQDKTRLKK-CHIAVGSPGRIKQLIELDYLNPGSIRLFILDEADKLLEEGS 183 Query: 197 FKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR 243 F+EQI +Y LP + Q++ +SAT P + K+M DP + + Sbjct: 184 FQEQINWIYSSLPASKQMLAVSATYPEFLANALTKYMRDPTFVRLNS 230 >1Q0U-A nrPDB Length = 219 Score = 229 bits (583), Expect = 2e-60, Method: Composition-based stats. Identities = 69/210 (32%), Positives = 113/210 (53%), Gaps = 4/210 (1%) Query: 36 VTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSIS 95 F + ++ I F KP+ IQ+R I ++G ++ QSQ+GTGKT + + Sbjct: 2 AETQFTRFPFQPFIIEAIKTLRFYKPTEIQERIIPGALRGESMVGQSQTGTGKTHAYLLP 61 Query: 96 VLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMN----VQCHACIGGTNVGEDIR 151 +++ + + E QA+I APTRELA QI L + + + IGGT+ + + Sbjct: 62 IMEKIKPERAEVQAVITAPTRELATQIYHETLKITKFCPKDRMIVARCLIGGTDKQKALE 121 Query: 152 KLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPA 211 KL+ H+V GTPGR+ D IR ++L +LV+DEAD ML+ GF + + +P Sbjct: 122 KLNVQPHIVIGTPGRINDFIREQALDVHTAHILVVDEADLMLDMGFITDVDQIAARMPKD 181 Query: 212 TQVVLISATLPHEILEMTNKFMTDPIRILV 241 Q+++ SAT+P ++ K+M +P + V Sbjct: 182 LQMLVFSATIPEKLKPFLKKYMENPTFVHV 211 >5AGA-A nrPDB Length = 830 Score = 224 bits (570), Expect = 8e-59, Method: Composition-based stats. Identities = 85/434 (19%), Positives = 180/434 (41%), Gaps = 100/434 (23%) Query: 44 GLREDLLRGIYAYGFEKPSAIQQRAI--KQIIKGRDVIAQSQSGTGKTATFSISVLQCLD 101 GL + +L +++G +K Q + Q+++G++++ + + GKT + +L+ + Sbjct: 11 GLPKAVLEKYHSFGVKKMFEWQAECLLLGQVLEGKNLVYSAPTSAGKTLVAELLILKRV- 69 Query: 102 IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVA 161 +++R+ +AL + P +A + + L +L + ++ +G T+ LD + Sbjct: 70 LEMRK-KALFILPFVSVAKEKKYYLQSLFQEVGIKVDGYMGSTSPSRHFSSLDIAVCTIE 128 Query: 162 GTPGRVFDMIRRRSLRTRAIKMLVLDEADEM--LNKGFKEQIY----------------D 203 G + +I + + M+V+DE + ++G+ ++ D Sbjct: 129 RANGLINRLIEENKMDL--LGMVVVDELHMLGDSHRGYLLELLLTKICYITRKSASCQAD 186 Query: 204 VYRYLPPATQVVLISATLPHEILEMTNKFMT--------DPIRIL--VKRD----ELTLE 249 + L A Q+V +SATLP+ LE+ ++ P+ +L VK + +++ Sbjct: 187 LASSLSNAVQIVGMSATLPN--LELVASWLNAELYHTDFRPVPLLESVKVGNSIYDSSMK 244 Query: 250 GIKQF--FVAVEREEWKFDTLCDLYDTLTITQAV-IFCNTKRKVDWLTEKM--------- 297 +++F + V+ +E +LC Y+T+ +V +FC +K+ + L + + Sbjct: 245 LVREFEPMLQVKGDEDHVVSLC--YETICDNHSVLLFCPSKKWCEKLADIIAREFYNLHH 302 Query: 298 ----------------------------------------REANFTVSSMHGDMPQKERE 317 + + V+ H + +ER+ Sbjct: 303 QAEGLVKPSECPPVILEQKELLEVMDQLRRLPSGLDSVLQKTVPWGVAFHHAGLTFEERD 362 Query: 318 SIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL----PNNRELYIHRIGRSGRYG- 372 I FR G RVL +T + G+++P +II + P + Y +GR+GR G Sbjct: 363 IIEGAFRQGLIRVLAATSTLSSGVNLPARRVIIRTPIFGGRPLDILTYKQMVGRAGRKGV 422 Query: 373 -RKGVAINFVKNDD 385 G +I KN + Sbjct: 423 DTVGESILICKNSE 436 >3FMO-B nrPDB Length = 300 Score = 220 bits (562), Expect = 7e-58, Method: Composition-based stats. Identities = 77/241 (31%), Positives = 129/241 (53%), Gaps = 11/241 (4%) Query: 12 SARKRLLKEEDMTKVEFETSEEVDV---TPTFDTMGLREDLLRGIYAYGFEKPSAIQQRA 68 + R ++ +VE + +F+ + L+ LL+G+YA GF +PS IQ+ A Sbjct: 63 NKLIRSNLVDNTNQVEVLQRDPNSPLYSVKSFEELRLKPQLLQGVYAMGFNRPSKIQENA 122 Query: 69 IKQII--KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 + ++ +++IAQSQSGTGKTA F +++L ++ + Q L L+PT ELA+Q K + Sbjct: 123 LPLMLAEPPQNLIAQSQSGTGKTAAFVLAMLSQVEPANKYPQCLCLSPTYELALQTGKVI 182 Query: 127 LALGD-YMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIKML 184 +G Y ++ + G + R + +V GTPG V D + + + + IK+ Sbjct: 183 EQMGKFYPELKLAYAVRGNKLE---RGQKISEQIVIGTPGTVLDWCSKLKFIDPKKIKVF 239 Query: 185 VLDEADEML-NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR 243 VLDEAD M+ +G ++Q + R LP Q++L SAT + + K + DP I +KR Sbjct: 240 VLDEADVMIATQGHQDQSIRIQRMLPRNCQMLLFSATFEDSVWKFAQKVVPDPNVIKLKR 299 Query: 244 D 244 + Sbjct: 300 E 300 >3FHC-B nrPDB Length = 235 Score = 220 bits (561), Expect = 7e-58, Method: Composition-based stats. Identities = 75/215 (34%), Positives = 122/215 (56%), Gaps = 8/215 (3%) Query: 37 TPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQII--KGRDVIAQSQSGTGKTATFSI 94 +F+ + L+ LL+G+YA GF +PS IQ+ A+ ++ +++IAQSQSGTGKTA F + Sbjct: 24 VKSFEELRLKPQLLQGVYAMGFNRPSKIQENALPLMLAEPPQNLIAQSQSGTGKTAAFVL 83 Query: 95 SVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGD-YMNVQCHACIGGTNVGEDIRKL 153 ++L ++ + Q L L+PT ELA+Q K + +G Y ++ + G + R Sbjct: 84 AMLSQVEPANKYPQCLCLSPTYELALQTGKVIEQMGKFYPELKLAYAVRGNKLE---RGQ 140 Query: 154 DYGQHVVAGTPGRVFDMIRR-RSLRTRAIKMLVLDEADEML-NKGFKEQIYDVYRYLPPA 211 + +V GTPG V D + + + + IK+ VLDEAD M+ +G ++Q + R LP Sbjct: 141 KISEQIVIGTPGTVLDWCSKLKFIDPKKIKVFVLDEADVMIATQGHQDQSIRIQRMLPRN 200 Query: 212 TQVVLISATLPHEILEMTNKFMTDPIRILVKRDEL 246 Q++L SAT + + K + DP I +KR+E Sbjct: 201 CQMLLFSATFEDSVWKFAQKVVPDPNVIKLKREEE 235 >2KBE-A nrPDB Length = 226 Score = 220 bits (560), Expect = 1e-57, Method: Composition-based stats. Identities = 79/210 (37%), Positives = 129/210 (61%), Gaps = 7/210 (3%) Query: 37 TPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG--RDVIAQSQSGTGKTATFSI 94 +FD +GL +LL+GIYA F+KPS IQ+RA+ ++ R++IAQSQSGTGKTA FS+ Sbjct: 21 AKSFDELGLAPELLKGIYAMKFQKPSKIQERALPLLLHNPPRNMIAQSQSGTGKTAAFSL 80 Query: 95 SVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLD 154 ++L ++ + QA+ LAP+RELA Q + + +G + + + + E ++++ Sbjct: 81 TMLTRVNPEDASPQAICLAPSRELARQTLEVVQEMGKFTKITSQLIV--PDSFEKNKQIN 138 Query: 155 YGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLN-KGFKEQIYDVYRYLPPATQ 213 V+ GTPG V D++RR+ ++ + IK+ VLDEAD ML+ +G +Q V R+LP TQ Sbjct: 139 --AQVIVGTPGTVLDLMRRKLMQLQKIKIFVLDEADNMLDQQGLGDQCIRVKRFLPKDTQ 196 Query: 214 VVLISATLPHEILEMTNKFMTDPIRILVKR 243 +VL SAT + + K + + + ++ Sbjct: 197 LVLFSATFADAVRQYAKKIVPNANTLELQT 226 >2PL3-A nrPDB Length = 236 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 59/213 (27%), Positives = 106/213 (49%), Gaps = 6/213 (2%) Query: 34 VDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFS 93 V+ F L + L+G+ + + IQ++ I ++G+DV+ +++G+GKT F Sbjct: 21 VNEITRFSDFPLSKKTLKGLQEAQYRLVTEIQKQTIGLALQGKDVLGAAKTGSGKTLAFL 80 Query: 94 ISVLQCLD----IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGED 149 + VL+ L LI++PTRELA Q + L +G + IGG ++ + Sbjct: 81 VPVLEALYRLQWTSTDGLGVLIISPTRELAYQTFEVLRKVGKNHDFSAGLIIGGKDLKHE 140 Query: 150 IRKLDYGQHVVAGTPGRVFDMIRRR-SLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYL 208 +++ +++ TPGR+ + S ++MLVLDEAD +L+ GF + + V L Sbjct: 141 AERINN-INILVCTPGRLLQHMDETVSFHATDLQMLVLDEADRILDMGFADTMNAVIENL 199 Query: 209 PPATQVVLISATLPHEILEMTNKFMTDPIRILV 241 P Q +L SAT + ++ + +P + V Sbjct: 200 PKKRQTLLFSATQTKSVKDLARLSLKNPEYVWV 232 >3LY5-A nrPDB Length = 262 Score = 212 bits (541), Expect = 2e-55, Method: Composition-based stats. Identities = 63/233 (27%), Positives = 118/233 (50%), Gaps = 8/233 (3%) Query: 11 GSARKRLLKEEDMTKVEFETSEEVDVTPT-FDTMG--LREDLLRGIYAYGFEKPSAIQQR 67 + K E++ T F ++ + E+ L+ I GF + IQ + Sbjct: 24 NNVEKPDNDEDESEVPSLPLGLTGAFEDTSFASLCNLVNENTLKAIKEMGFTNMTEIQHK 83 Query: 68 AIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD----IQVRETQALILAPTRELAVQIQ 123 +I+ +++GRD++A +++G+GKT F I ++ + + T LIL+PTRELA+Q Sbjct: 84 SIRPLLEGRDLLAAAKTGSGKTLAFLIPAVELIVKLRFMPRNGTGVLILSPTRELAMQTF 143 Query: 124 KGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RSLRTRAIK 182 L L + +GG+N + +KL G +++ TPGR+ D ++ + ++ Sbjct: 144 GVLKELMTHHVHTYGLIMGGSNRSAEAQKLGNGINIIVATPGRLLDHMQNTPGFMYKNLQ 203 Query: 183 MLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTD 235 LV+DEAD +L+ GF+E++ + + LP Q +L SAT ++ ++ + Sbjct: 204 CLVIDEADRILDVGFEEELKQIIKLLPTRRQTMLFSATQTRKVEDLARISLKK 256 >4Q48-A nrPDB Length = 525 Score = 210 bits (536), Expect = 6e-55, Method: Composition-based stats. Identities = 60/356 (16%), Positives = 130/356 (36%), Gaps = 31/356 (8%) Query: 49 LLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQ 108 LL+ I+ G+ +Q ++Q+ +G + + +G GK+ + + L +R Sbjct: 15 LLQTIW--GYPAFRGVQGEIVQQVAEGGNALVLMPTGGGKSLCYQLPSL------LRPGT 66 Query: 109 ALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ-----HVVAGT 163 ++++P L L N A + T + + R+++ ++ Sbjct: 67 GIVVSPLIALMKDQVDTLRQ-----NGVRAAFLNSTLLPHEAREVEDALLRGDLDLLYVA 121 Query: 164 PGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQIYD--VYRYLPPATQVVLISA 219 P R+ L + + +DEA + G F+ + V P V ++A Sbjct: 122 PERLLMPRTLDLLERAPVALFAIDEAHCVSQWGHDFRPEYQQLSVLAERFPELPRVALTA 181 Query: 220 TLPHEILEMTNKFMT---DPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT 276 T + P + I+ + K L + + Sbjct: 182 TADERTRADIKSVLRLEDAPQFV----SSFDRPNIQYRVGLKDSP--KTQLLHFIREEHP 235 Query: 277 ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDV 336 +++C +++ V+ + ++ + H + ER ++ + F + ++ +T Sbjct: 236 GDAGIVYCLSRKSVEETAKWLQAQGIDALAYHAGLSSTERNNVQERFLNEEGVIVCATVA 295 Query: 337 WARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392 + G+D P V + + DLP + E Y GR+GR G A D+ +R + Sbjct: 296 FGMGIDKPNVRFVAHLDLPKSMEGYYQETGRAGRDGLPSTAWMVYGLSDVVNVRRM 351 >2WWY-A nrPDB Length = 591 Score = 208 bits (530), Expect = 3e-54, Method: Composition-based stats. Identities = 55/386 (14%), Positives = 143/386 (37%), Gaps = 39/386 (10%) Query: 30 TSEEVDVTPTFDTMGLR---EDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGT 86 + + +D+L+ ++ EK +Q I + G++V +G Sbjct: 13 EYDSSPAAWNKEDFPWSGKVKDILQNVFKL--EKFRPLQLETINVTMAGKEVFLVMPTGG 70 Query: 87 GKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNV 146 GK+ + + L + L++ P L L LG + ++ Sbjct: 71 GKSLCYQLPAL------CSDGFTLVICPLISLMEDQLMVLKQLGI-----SATMLNASSS 119 Query: 147 GEDIR-------KLDYGQHVVAGTPGRV---FDMIRR--RSLRTRAIKMLVLDEADEMLN 194 E ++ + ++ TP ++ + R ++ R + +DE Sbjct: 120 KEHVKWVHAEMVNKNSELKLIYVTPEKIAKSKMFMSRLEKAYEARRFTRIAVDEVHCCSQ 179 Query: 195 KG--FKEQIYD--VYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEG 250 G F+ + + P ++ ++AT + +L K + + Sbjct: 180 WGHDFRPDYKALGILKRQFPNASLIGLTATATNHVLTDAQKILCI-EKCFTFTASFNRPN 238 Query: 251 IKQFFVAVEREEWKFDTLCDLYDTLTI----TQAVIFCNTKRKVDWLTEKMREANFTVSS 306 + ++ ++ D + D+ + +I+C +++ + +T ++ + Sbjct: 239 L--YYEVRQKPSNTEDFIEDIVKLINGRYKGQSGIIYCFSQKDSEQVTVSLQNLGIHAGA 296 Query: 307 MHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIG 366 H ++ +++ ++ +++ + +V+++T + G+D P V +I++ + + E Y G Sbjct: 297 YHANLEPEDKTTVHRKWSANEIQVVVATVAFGMGIDKPDVRFVIHHSMSKSMENYYQESG 356 Query: 367 RSGRYGRKGVAINFVKNDDIRILRDI 392 R+GR K I + DI + + Sbjct: 357 RAGRDDMKADCILYYGFGDIFRISSM 382 >5V9X-A nrPDB Length = 877 Score = 207 bits (528), Expect = 6e-54, Method: Composition-based stats. Identities = 77/416 (18%), Positives = 156/416 (37%), Gaps = 82/416 (19%) Query: 41 DTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCL 100 D +G L R + F P+ Q A I +G + + + +G+GKT + + L Sbjct: 28 DPLGRFSALTREWFTTAFAAPTPAQADAWSAISEGNNTLVIAPTGSGKTLAAFLWAIDRL 87 Query: 101 DIQVRET----QALILAPTRELAVQIQK-------GLLALGDYMNVQCHACIGGTNVGED 149 RE Q L ++P + LAV +++ G+ + + + + G G+ Sbjct: 88 ADPAREPSQGTQVLYVSPLKALAVDVERNLRTPLTGITRVAERHGLPAPSITVGVRSGDT 147 Query: 150 IRK-----LDYGQHVVAGTPGRVFDMIRRRSLR-TRAIKMLVLDE----------ADEML 193 + V+ TP +F M+ + +++ +++DE A L Sbjct: 148 PPNQRRAMIANPPDVLITTPESLFLMLTSAARETLTSVRTVIVDEVHAVAATKRGAHLAL 207 Query: 194 NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTD--PIRILVKRDELTLEGI 251 + +Q+ D PA ++ L + P E +F++ P I+ T + Sbjct: 208 SLERLDQLLDT-----PAQRIGLSATVRPPEE---VARFLSGQAPTTIVCPPAAKTFDLS 259 Query: 252 KQFFVA-----VEREEWK--FDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREAN--- 301 Q V W + + DL + +++F N++R + LT ++ E + Sbjct: 260 VQVPVPDMANLDNNSIWPDVEERIVDLVEAH--NSSIVFANSRRLAERLTSRLNEIHAER 317 Query: 302 --------------------------------FTVSSMHGDMPQKERESIMKEFRSGASR 329 + HG + +++R + + +SG R Sbjct: 318 SGIELPAGPNPEVGGGAPAHLMGSGQANGAPPLLARAHHGSVSKEQRAQVEDDLKSGRLR 377 Query: 330 VLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSG-RYGRKGVAINFVKND 384 +++T G+D+ V L+I + P + + R+GR+G + G + F K+ Sbjct: 378 AVVATSSLELGIDMGAVDLVIQVEAPPSVASGLQRVGRAGHQVGEISQGVLFPKHR 433 >1GM5-A nrPDB Length = 780 Score = 202 bits (513), Expect = 3e-52, Method: Composition-based stats. Identities = 67/321 (20%), Positives = 139/321 (43%), Gaps = 27/321 (8%) Query: 76 RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 + + Q G+GKT +++L + Q + PT LA+Q + + N+ Sbjct: 390 MNRLLQGDVGSGKTVVAQLAILDNYEAGF---QTAFMVPTSILAIQHYRRTVESFSKFNI 446 Query: 136 QCHACIGGTNVGEDIR---KLDYGQ-HVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE 191 IG T E + L GQ VV GT + + + + + ++++DE Sbjct: 447 HVALLIGATTPSEKEKIKSGLRNGQIDVVIGTHALI-----QEDVHFKNLGLVIIDEQHR 501 Query: 192 --------MLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR 243 ++NKG ++ D + AT + A + L++T P R V+ Sbjct: 502 FGVKQREALMNKG---KMVDTL--VMSATPIPRSMALAFYGDLDVTVIDEMPPGRKEVQT 556 Query: 244 DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFT 303 + ++ + + + V +E + +Y + + + + ++L++++ F Sbjct: 557 MLVPMDRVNEVYEFVRQEVMRGGQAFIVYPLIEESDKLNVKSAVEMYEYLSKEVF-PEFK 615 Query: 304 VSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIH 363 + MHG + Q+E++ +M EF G +L+ST V G+DVP+ ++++ + +H Sbjct: 616 LGLMHGRLSQEEKDRVMLEFAEGRYDILVSTTVIEVGIDVPRANVMVIENPERFGLAQLH 675 Query: 364 RI-GRSGRYGRKGVAINFVKN 383 ++ GR GR G++ V + Sbjct: 676 QLRGRVGRGGQEAYCFLVVGD 696 >3DKP-A nrPDB Length = 245 Score = 196 bits (498), Expect = 2e-50, Method: Composition-based stats. Identities = 55/230 (23%), Positives = 113/230 (49%), Gaps = 12/230 (5%) Query: 25 KVEFETSEEVDVTPTFD----TMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIA 80 K+ + ++ D TF + LL+ I GF+ P+ IQ +AI ++ GR+++A Sbjct: 12 KIHVQGTDLPDPIATFQQLDQEYKINSRLLQNILDAGFQMPTPIQMQAIPVMLHGRELLA 71 Query: 81 QSQSGTGKTATFSISVLQCLD-IQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHA 139 + +G+GKT FSI +L L + +ALI++PTRELA QI + L+ + + + H Sbjct: 72 SAPTGSGKTLAFSIPILMQLKQPANKGFRALIISPTRELASQIHRELIKISEGTGFRIHM 131 Query: 140 CI-GGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRR--SLRTRAIKMLVLDEADEMLN-- 194 + K ++ TP R+ ++++ + +++ LV+DE+D++ Sbjct: 132 IHKAAVAAKKFGPKSSKKFDILVTTPNRLIYLLKQDPPGIDLASVEWLVVDESDKLFEDG 191 Query: 195 -KGFKEQIYDVYRY-LPPATQVVLISATLPHEILEMTNKFMTDPIRILVK 242 GF++Q+ ++ + + SAT +++ + + + I + + Sbjct: 192 KTGFRDQLASIFLACTSHKVRRAMFSATFAYDVEQWCKLNLDNVISVSIG 241 >5LBA-B nrPDB Length = 445 Score = 192 bits (489), Expect = 2e-49, Method: Composition-based stats. Identities = 67/399 (16%), Positives = 144/399 (36%), Gaps = 44/399 (11%) Query: 39 TFDTMGLREDLLRGIYAYGFEKP-SAIQQRAIKQIIKG-RDVIAQSQSGTGKTATFSISV 96 + D L+ + +GF+ + +Q+ A ++KG +DV +G GK+ + + Sbjct: 1 SMDPERRVRSTLKKV--FGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPA 58 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALG---DYMNVQCHACIGGTNVGEDIRKL 153 L + + ++++P L LL L +N + A + D+ + Sbjct: 59 L------LAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQER-KELLADLERE 111 Query: 154 DYGQHVVAGTPG---------RVFDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQIY 202 ++ TP + ++ R L LV+DEA + G F+ Sbjct: 112 KPQTKILYITPEMAASSSFQPTLNSLVSRHLLS-----YLVVDEAHCVSQWGHDFRPDYL 166 Query: 203 DV--YRYLPPATQVVLISATLPHEILE--MTNKFMTDPIRIL---VKRDELTLEGIKQFF 255 + R V ++AT ++ E + P+ I R L + QF Sbjct: 167 RLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYD--VQFK 224 Query: 256 VAVERE-----EWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGD 310 + ++ L D +++C T+ + L ++ + H Sbjct: 225 ELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAG 284 Query: 311 MPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR 370 + ER + ++ V+++T + G+D V + ++++ + Y GR+GR Sbjct: 285 LKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGR 344 Query: 371 YGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVAD 409 G+ + +D + + + ++ E N A Sbjct: 345 DGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKAS 383 >5LB8-A nrPDB Length = 518 Score = 192 bits (489), Expect = 2e-49, Method: Composition-based stats. Identities = 67/399 (16%), Positives = 144/399 (36%), Gaps = 44/399 (11%) Query: 39 TFDTMGLREDLLRGIYAYGFEKP-SAIQQRAIKQIIKG-RDVIAQSQSGTGKTATFSISV 96 + D L+ + +GF+ + +Q+ A ++KG +DV +G GK+ + + Sbjct: 1 SMDPERRVRSTLKKV--FGFDSFKTPLQESATMAVVKGNKDVFVCMPTGAGKSLCYQLPA 58 Query: 97 LQCLDIQVRETQALILAPTRELAVQIQKGLLALG---DYMNVQCHACIGGTNVGEDIRKL 153 L + + ++++P L LL L +N + A + D+ + Sbjct: 59 L------LAKGITIVVSPLIALIQDQVDHLLTLKVRVSSLNSKLSAQER-KELLADLERE 111 Query: 154 DYGQHVVAGTPG---------RVFDMIRRRSLRTRAIKMLVLDEADEMLNKG--FKEQIY 202 ++ TP + ++ R L LV+DEA + G F+ Sbjct: 112 KPQTKILYITPEMAASSSFQPTLNSLVSRHLLS-----YLVVDEAHCVSQWGHDFRPDYL 166 Query: 203 DV--YRYLPPATQVVLISATLPHEILE--MTNKFMTDPIRIL---VKRDELTLEGIKQFF 255 + R V ++AT ++ E + P+ I R L + QF Sbjct: 167 RLGALRSRLGHAPCVALTATATPQVQEDVFAALHLKKPVAIFKTPCFRANLFYD--VQFK 224 Query: 256 VAVERE-----EWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGD 310 + ++ L D +++C T+ + L ++ + H Sbjct: 225 ELISDPYGNLKDFCLKALGQEADKGLSGCGIVYCRTREACEQLAIELSCRGVNAKAYHAG 284 Query: 311 MPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR 370 + ER + ++ V+++T + G+D V + ++++ + Y GR+GR Sbjct: 285 LKASERTLVQNDWMEEKVPVIVATISFGMGVDKANVRFVAHWNIAKSMAGYYQESGRAGR 344 Query: 371 YGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVAD 409 G+ + +D + + + ++ E N A Sbjct: 345 DGKPSWCRLYYSRNDRDQVSFLIRKEVAKLQEKRGNKAS 383 >5LST-A nrPDB Length = 693 Score = 190 bits (484), Expect = 7e-49, Method: Composition-based stats. Identities = 65/372 (17%), Positives = 131/372 (35%), Gaps = 33/372 (8%) Query: 46 REDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVR 105 ++ + + G + Q+RA+ +I+ G + +G GK+ + + L L + Sbjct: 43 PAEVFQALEQLGHQAFRPGQERAVMRILSGISTLLVLPTGAGKSLCYQLPAL--LYSRRS 100 Query: 106 ETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDY----GQHVVA 161 L+++P L GL ++ G + L HV+ Sbjct: 101 PCLTLVVSPLLSLMDDQVSGL-----PPCLKAACIHSGMTRKQRESVLQKIRAAQVHVLM 155 Query: 162 GTPGRVF-DMIRRRSLRTRAIKMLVLDEADEMLNK--GFKE---QIYDVYRYLPPATQVV 215 TP + + + + +DEA + F+ ++ V R + Sbjct: 156 LTPEALVGAGGLPPAAQLPPVAFACIDEAHCLSQWSHNFRPCYLRVCKVLRERMGVHCFL 215 Query: 216 LISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTL 275 ++AT + + + + + TL Sbjct: 216 GLTATATRRTASDVAQHLAVAEEPDLHGPAPVPTNLHLSVSMDRDTDQALLTLLQGKRFQ 275 Query: 276 TITQAVIFCNTKRKVDWLTEKMR--------------EANFTVSSMHGDMPQKERESIMK 321 + +I+CN + + + +R T + H M +ER + + Sbjct: 276 NLDSIIIYCNRREDTERIAALLRTCLHAAWVPGSGGRAPKTTAEAYHAGMCSRERRRVQR 335 Query: 322 EFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFV 381 F G RV+++T + GLD P V +++ LP + E Y+ +GR+GR G+ F+ Sbjct: 336 AFMQGQLRVVVATVAFGMGLDRPDVRAVLHLGLPPSFESYVQAVGRAGRDGQPAHCHLFL 395 Query: 382 KN--DDIRILRD 391 + +D+R LR Sbjct: 396 QPQGEDLRELRR 407 >2P6R-A nrPDB Length = 702 Score = 137 bits (344), Expect = 1e-32, Method: Composition-based stats. Identities = 69/385 (17%), Positives = 146/385 (37%), Gaps = 59/385 (15%) Query: 53 IYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALIL 112 + G E+ Q A++++ G++++ + GKT +++ + ++ ++L + Sbjct: 18 LKEEGIEELFPPQAEAVEKVFSGKNLLLAMPTAAGKTLLAEMAM---VREAIKGGKSLYV 74 Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172 P R LA + + + + ++ G ++ ++ T + +IR Sbjct: 75 VPLRALAGEKYESFKKW-EKIGLRIGISTGDYESRDEHLG---DCDIIVTTSEKADSLIR 130 Query: 173 RRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVY----RYLPPATQVVLISATLPHEILEM 228 R+ +A+ LV+DE +L+ + ++ R + A +V+ +SAT P+ + E+ Sbjct: 131 NRASWIKAVSCLVVDEIH-LLDSEKRGATLEILVTKMRRMNKALRVIGLSATAPN-VTEI 188 Query: 229 TNKFMTDPI----RILVKRDELTLEGIKQFF--VAVEREEWKFDTLCDLYDTLTITQAVI 282 D R + + + EG + F KF+ L + ++ Sbjct: 189 AEWLDADYYVSDWRPVPLVEGVLCEGTLELFDGAFSTSRRVKFEELVEEC-VAENGGVLV 247 Query: 283 FCNTKRKVDWLTEKMREANFT------------------------------VSSMHGDMP 312 F +T+R + K+ + H + Sbjct: 248 FESTRRGAEKTAVKLSAITAKYVENEGLEKAILEENEGEMSRKLAECVRKGAAFHHAGLL 307 Query: 313 QKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII----NYDLPNNRE---LYIHRI 365 +R + FR G +V+++T A G+++P +I+ +D + R Y Sbjct: 308 NGQRRVVEDAFRRGNIKVVVATPTLAAGVNLPARRVIVRSLYRFDGYSKRIKVSEYKQMA 367 Query: 366 GRSGRYG--RKGVAINFVKNDDIRI 388 GR+GR G +G AI V D I Sbjct: 368 GRAGRPGMDERGEAIIIVGKRDREI 392 >2ZJ8-A nrPDB Length = 720 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 70/419 (16%), Positives = 166/419 (39%), Gaps = 62/419 (14%) Query: 41 DTMGLREDLLRGIYAYGFEKPSAIQQRAIKQ-IIKGRDVIAQSQSGTGKTATFSISVLQC 99 D + + E + + G E Q A+K I++G++ + + +GKT I+++ Sbjct: 4 DELRVDERIKSTLKERGIESFYPPQAEALKSGILEGKNALISIPTASGKTLIAEIAMVHR 63 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159 + Q +A+ + P + LA + + + + ++ G + ++ + Sbjct: 64 ILTQ--GGKAVYIVPLKALAEEKFQEFQDW-EKIGLRVAMATGDYDSKDEWLGKY---DI 117 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISA 219 + T + ++R S + +K+LV DE + ++ + + ++ Q++ +SA Sbjct: 118 IIATAEKFDSLLRHGSSWIKDVKILVADEIHLIGSRDRGATLEVILAHMLGKAQIIGLSA 177 Query: 220 TL--PHEILEM--TNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDL-YDT 274 T+ P E+ E ++D + ++R + F + +F + +L YD Sbjct: 178 TIGNPEELAEWLNAELIVSDWRPVKLRRGVFY----QGFVTWEDGSIDRFSSWEELVYDA 233 Query: 275 LTITQA-VIFCNTKRKVDWLT--------EKMREANF----------------------- 302 + + +IF N +RK + + + + Sbjct: 234 IRKKKGALIFVNMRRKAERVALELSKKVKSLLTKPEIRALNELADSLEENPTNEKLAKAI 293 Query: 303 --TVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN-------YD 353 V+ H + + ER + + FR G + +++T + G++ P +II + Sbjct: 294 RGGVAFHHAGLGRDERVLVEENFRKGIIKAVVATPTLSAGINTPAFRVIIRDIWRYSDFG 353 Query: 354 LPNNRELYIH-RIGRSGR--YGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVAD 409 + + +H +GR+GR Y G I +DD R + + Y + +++ +++ Sbjct: 354 MERIPIIEVHQMLGRAGRPKYDEVGEGIIVSTSDDPREV--MNHYIFGKPEKLFSQLSN 410 >2VA8-A nrPDB Length = 715 Score = 127 bits (319), Expect = 1e-29, Method: Composition-based stats. Identities = 64/432 (14%), Positives = 153/432 (35%), Gaps = 73/432 (16%) Query: 41 DTMGLREDLLRGIYAYGFEKPSAIQQRAIK-QIIKGRDVIAQSQSGTGKTATFSISVLQC 99 + + L +++ I G +K + Q A+K +++G ++ S +G+GKT + ++ Sbjct: 11 EDLKLPSNVIEIIKKRGIKKLNPPQTEAVKKGLLEGNRLLLTSPTGSGKTLIAEMGIISF 70 Query: 100 LDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHV 159 L +A+ + P R L + + + + G + + K + Sbjct: 71 LL--KNGGKAIYVTPLRALTNEKY-LTFKDWELIGFKVAMTSGDYDTDDAWLK---NYDI 124 Query: 160 VAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISA 219 + T ++ + R R + VLDE + + + V ++ +SA Sbjct: 125 IITTYEKLDSLWRHRPEWLNEVNYFVLDELHYLNDPERGPVVESV-TIRAKRRNLLALSA 183 Query: 220 TLPH--------EILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFD----T 267 T+ + + + P+ ++ + + + + K Sbjct: 184 TISNYKQIAKWLGAEPVATNW--RPVPLIEGVIYPERKKKEYNVIFKDNTTKKVHGDDAI 241 Query: 268 LCDLYDTLTIT-QAVIFCNTKRKVDWLT-EKMREANF----------------------- 302 + D+L+ Q ++F N+++ + + NF Sbjct: 242 IAYTLDSLSKNGQVLVFRNSRKMAESTALKIANYMNFVSLDENALSEILKQLDDIEEGGS 301 Query: 303 ------------TVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII 350 V+ H + + R+ I + FR +V+++T A G+++P ++II Sbjct: 302 DEKELLKSLISKGVAYHHAGLSKALRDLIEEGFRQRKIKVIVATPTLAAGVNLPARTVII 361 Query: 351 --NYDLPNNRELYI---------HRIGRSGR--YGRKGVAINFVKNDDIRILRDIEQYYS 397 Y Y GR+GR + + G +I V++ + + R ++Y Sbjct: 362 GDIYRFNKKIAGYYDEIPIMEYKQMSGRAGRPGFDQIGESIVVVRDKE-DVDRVFKKYVL 420 Query: 398 TQIDEMPMNVAD 409 + ++ + + Sbjct: 421 SDVEPIESKLGS 432 >5JCF-A nrPDB Length = 701 Score = 118 bits (296), Expect = 4e-27, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 81/191 (42%), Gaps = 29/191 (15%) Query: 244 DELTLEGIKQFFVAVEREEWKFDTLCDLYDTL-------TITQAVIFCNTKRKV----DW 292 L KQ + E+ + L L +TL + +IF T++ W Sbjct: 359 MRLFHAKKKQLKELARKPEYDNEKLMKLRNTLMEEFTKTEEPRGIIFTKTRQSALALYHW 418 Query: 293 LTEKMR------EANFTVSSMHGD----MPQKERESIMKEFRSGASRVLISTDVWARGLD 342 + + + +A+F + + H M Q E+ ++ +FR G+ +LI+T V GLD Sbjct: 419 IMDNPKFEEVGIKAHFLIGAGHNSETKPMTQNEQREVIDKFRGGSINLLIATTVAEEGLD 478 Query: 343 VPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI------NFVKNDDIRILRDIEQYY 396 + + +++I Y L N + GR+ R A+ V+ +D+ I R+ Y Sbjct: 479 IKECNIVIRYGLVTNEIAMVQARGRA-RADESTYALVASSGSGAVEREDVNIFRENMMYK 537 Query: 397 S-TQIDEMPMN 406 + ++ EMP Sbjct: 538 AIRRVQEMPPE 548 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 25/169 (14%), Positives = 52/169 (30%), Gaps = 10/169 (5%) Query: 55 AYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVR---ETQALI 111 A G Q K + G ++I +G+GKT LD + + + + ++ Sbjct: 2 AMGDLTLRDYQMEVAKPALNGENIIICLPTGSGKTRVAVYITKDHLDKKRKASEQGKVIV 61 Query: 112 LAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGT-----PGR 166 L L Q + Q G + + ++ V+ T Sbjct: 62 LVNKVPLVEQHLRKEFNPFLKHWYQVIGLSGDSELKISFPEVVKRYDVIICTAQILENSL 121 Query: 167 VFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYD--VYRYLPPATQ 213 + S+R ++++D+ +G I + + Q Sbjct: 122 LNATEEDESVRLSDFSLIIIDQCHHTQKEGVYNNIMRRYLKEKIKNRKQ 170 >4GL2-A nrPDB Length = 699 Score = 115 bits (287), Expect = 5e-26, Method: Composition-based stats. Identities = 45/230 (19%), Positives = 87/230 (37%), Gaps = 32/230 (13%) Query: 200 QIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR---DELTLEGIKQFFV 256 QI D R + T + + + + P+++ L E K Sbjct: 312 QINDTIRMIDAYTHLETFYNEEKDKKFAVIEDDLKKPLKLDETDRFLMTLFFENNKMLKR 371 Query: 257 AVEREEWKFDTLCDLYDTL--------TITQAVIFCNTKRKV----DWLTEKMREANFTV 304 E E++ + L L +T+ + +IF T++ W+TE + A V Sbjct: 372 LAENPEYENEKLTKLRNTIMEQYTRTEESARGIIFTKTRQSAYALSQWITENEKFAEVGV 431 Query: 305 SSMH----------GDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL 354 + H M Q E++ ++ +FR+G +LI+T V GLD+ + +++I Y L Sbjct: 432 KAHHLIGAGHSSEFKPMTQNEQKEVISKFRTGKINLLIATTVAEEGLDIKECNIVIRYGL 491 Query: 355 PNNRELYIHRIGRSGRYGRKGVAI------NFVKNDDIRILRDIEQYYST 398 N + GR+ R + ++ + + R+ Y + Sbjct: 492 VTNEIAMVQARGRA-RADESTYVLVAHSGSGVIERETVNDFREKMMYKAI 540 Score = 59.6 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 17/139 (12%), Positives = 45/139 (32%), Gaps = 9/139 (6%) Query: 62 SAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRE---TQALILAPTREL 118 Q + ++G+++I +G GKT LD + + + ++L L Sbjct: 9 RPYQMEVAQPALEGKNIIICLPTGCGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLL 68 Query: 119 AVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV------FDMIR 172 Q+ + + G T + ++ ++ T + + Sbjct: 69 VEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGE 128 Query: 173 RRSLRTRAIKMLVLDEADE 191 ++ ++++DE Sbjct: 129 DAGVQLSDFSLIIIDECHH 147 >1WP9-A nrPDB Length = 494 Score = 112 bits (280), Expect = 3e-25, Method: Composition-based stats. Identities = 44/187 (23%), Positives = 80/187 (42%), Gaps = 21/187 (11%) Query: 228 MTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTK 287 ++K M I +LV+ E+ L+ K + + + + ++ ++F N + Sbjct: 320 FSDKRMKKAISLLVQAKEIGLDHPKM--------DKLKEIIREQLQRKQNSKIIVFTNYR 371 Query: 288 RKVDWLTEKMREANFTVSSMHG--------DMPQKERESIMKEFRSGASRVLISTDVWAR 339 + ++ + G + Q+E++ I+ EF G VL++T V Sbjct: 372 ETAKKIVNELVKDGIKAKRFVGQASKENDRGLSQREQKLILDEFARGEFNVLVATSVGEE 431 Query: 340 GLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQ 399 GLDVP+V L++ Y+ + I R GR+GR+ V I K RD Y+S++ Sbjct: 432 GLDVPEVDLVVFYEPVPSAIRSIQRRGRTGRHMPGRVIILMAKGT-----RDEAYYWSSR 486 Query: 400 IDEMPMN 406 E M Sbjct: 487 QKEKIMQ 493 Score = 71.1 bits (173), Expect = 8e-13, Method: Composition-based stats. Identities = 26/128 (20%), Positives = 49/128 (38%), Gaps = 3/128 (2%) Query: 64 IQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQ 123 I Q I K + + +G GKT ++ + + L+LAPT+ L +Q Sbjct: 12 IYQEVIYAKCKETNCLIVLPTGLGKTLIAM--MIAEYRLTKYGGKVLMLAPTKPLVLQHA 69 Query: 124 KGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKM 183 + L + + A G + E + V+ TP + + + + + + Sbjct: 70 ESFRRLFNLPPEKIVALTGEKSPEERSKAWARA-KVIVATPQTIENDLLAGRISLEDVSL 128 Query: 184 LVLDEADE 191 +V DEA Sbjct: 129 IVFDEAHR 136 >6G19-A nrPDB Length = 696 Score = 108 bits (271), Expect = 3e-24, Method: Composition-based stats. Identities = 37/192 (19%), Positives = 75/192 (39%), Gaps = 30/192 (15%) Query: 244 DELTLEGIKQFFVAVEREEWKFDTLCDLYDTL--------TITQAVIFCNTKRKV----D 291 L + K E +++ + L L +T+ ++ +IF T++ Sbjct: 353 MNLFFDNKKMLKKLAENPKYENEKLIKLRNTILEQFTRSEESSRGIIFTKTRQSTYALSQ 412 Query: 292 WLTEKMREANFTVSSMH----------GDMPQKERESIMKEFRSGASRVLISTDVWARGL 341 W+ E + A V + H M Q E++ ++ +FR+G +LI+T V GL Sbjct: 413 WIMENAKFAEVGVKAHHLIGAGHSSEVKPMTQTEQKEVISKFRTGEINLLIATTVAEEGL 472 Query: 342 DVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI------NFVKNDDIRILRDIEQY 395 D+ + +++I Y L N + GR+ R + + + + R+ Y Sbjct: 473 DIKECNIVIRYGLVTNEIAMVQARGRA-RADESTYVLVTSSGSGVTEREIVNDFREKMMY 531 Query: 396 YST-QIDEMPMN 406 + ++ M Sbjct: 532 KAINRVQNMKPE 543 Score = 54.6 bits (130), Expect = 9e-08, Method: Composition-based stats. Identities = 20/141 (14%), Positives = 48/141 (34%), Gaps = 13/141 (9%) Query: 62 SAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVR---ETQALILAPTREL 118 Q + + G+++I +G+GKT LD + + + ++L L Sbjct: 4 RPYQMEVAQPALDGKNIIICLPTGSGKTRVAVYITKDHLDKKKQASESGKVIVLVNKVML 63 Query: 119 AVQIQKGLLALGDYMN--VQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV---FDMIRR 173 A Q+ + Y+ + G T + ++ V+ T + + Sbjct: 64 AEQLFR--KEFNPYLKKWYRIIGLSGDTQLKISFPEVVKSYDVIISTAQILENSLLNLES 121 Query: 174 R---SLRTRAIKMLVLDEADE 191 ++ ++++DE Sbjct: 122 GDDDGVQLSDFSLIIIDECHH 142 >6C90-A nrPDB Length = 734 Score = 95.8 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 68/464 (14%), Positives = 145/464 (31%), Gaps = 119/464 (25%) Query: 23 MTKVEFETSEEVD------VTPTFDT-MGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG 75 M +V+ ++ E V+ P + + L+ + + Y F A Q+ AI+ + Sbjct: 29 MPRVKVQSVETVEGCTHEVALPAEEDYLPLKPRVGKAAKEYPF-ILDAFQREAIQCVDNN 87 Query: 76 RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 + V+ + + GKT ++ L + R + +P + L+ Q + + + + Sbjct: 88 QSVLVSAHTSAGKTVCAEYAIALALREKQR---VIFTSPIKALSNQKYREMYEEFQDVGL 144 Query: 136 QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNK 195 ++ + T + M+ R S R + ++ DE M + Sbjct: 145 MTGDVT-----------INPTASCLVMTTEILRSMLYRGSEVMREVAWVIFDEIHYMRDS 193 Query: 196 GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTN---------------KFMTDP---- 236 + LP V +SAT+P+ + + P Sbjct: 194 ERGVVWEETIILLPDNVHYVFLSATIPNA-RQFAEWICHLHKQPCHVIYTDYRPTPLQHY 252 Query: 237 --------IRILVKRDELTLEGIKQFFVAVERE-------EWKFD-----------TLCD 270 + ++V + E + V R+ + K + Sbjct: 253 IFPAGGDGLHLVVDENGDFREDNFNTAMQVLRDAGDLAKGDQKGRKGGTKGPSNVFKIVK 312 Query: 271 LYDTLTITQAVIFCNTKRKVDWLTEKMREANF---------------------------- 302 + +IF +K+ + +M + +F Sbjct: 313 MIMERNFQPVIIFSFSKKDCEAYALQMTKLDFNTDEEKKMVEEVFSNAIDCLSDEDKKLP 372 Query: 303 -----------TVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN 351 + HG + +E+I F G + L +T+ +A G+++P ++ Sbjct: 373 QVEHVLPLLKRGIGIHHGGLLPILKETIEILFSEGLIKALFATETFAMGINMPA-RTVLF 431 Query: 352 YDLPN---------NRELYIHRIGRSGRYGR--KGVAINFVKND 384 + + YI GR+GR G +G+ I V Sbjct: 432 TNARKFDGKDFRWISSGEYIQMSGRAGRRGMDDRGIVILMVDEK 475 >5JBJ-A nrPDB Length = 680 Score = 94.6 bits (234), Expect = 6e-20, Method: Composition-based stats. Identities = 33/202 (16%), Positives = 73/202 (36%), Gaps = 29/202 (14%) Query: 230 NKFMTDPIRILVKRD-ELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT----ITQAVIFC 284 + DP + E ++ E + L ++ ++ ++F Sbjct: 319 KRDTKDPTERFLATTFEENRATLQALAGDQRYENPRLSKLEEILQEHFQPPGSSRGIVFT 378 Query: 285 NTKRKVDWLTEKMRE------ANFTVSSMHG--------DMPQKERESIMKEFRSGASRV 330 T++ L +++ + + + G M Q E++ ++ FR G + Sbjct: 379 KTRQSAHSLLSWLQDTAGLCGQHIRAAVLTGSGHSNQAKGMTQNEQQDVITLFRYGELNL 438 Query: 331 LISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILR 390 L ST V GLD+P+ ++++ Y L N + GR+ R ++ K + + R Sbjct: 439 LFSTSVAEEGLDIPECNIVVRYGLMTNEIAMVQAQGRA-RAQNSMYSVL-AKANSREVYR 496 Query: 391 D--------IEQYYSTQIDEMP 404 + + + + MP Sbjct: 497 EQLNESLVGLMERAIRAVQAMP 518 Score = 55.3 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 47/133 (35%), Gaps = 10/133 (7%) Query: 65 QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQI-Q 123 Q A+ ++GR+ I +G GKT + L+ R + +L L Q + Sbjct: 13 QLEAVAPALRGRNSIVWLPTGAGKTRAAVHVCRRHLE-GRRGGRVAVLVNKVHLVQQHLE 71 Query: 124 KGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMI-----RRRSLRT 178 K L D + A G ++ +L G VV T ++ + Sbjct: 72 KEFHVLRDA--FKVTAVSGDSSHKCFFGQLAKGSDVVICT-AQILQNALLSGEEEARVEL 128 Query: 179 RAIKMLVLDEADE 191 +LV+DE Sbjct: 129 TDFSLLVIDECHH 141 >1D9Z-A nrPDB Length = 657 Score = 93.1 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 70/351 (19%), Positives = 127/351 (36%), Gaps = 60/351 (17%) Query: 96 VLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDY 155 +Q ++ ++ E A + A + L Q + M + C G N + Sbjct: 258 AIQNIEQELEERLAELRAQGKLLEAQRLEQRTRYDLEMMREMGFCSGIENYSRHLALRPP 317 Query: 156 GQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV 215 G TP + D L +++DE+ L Q+ +Y QV+ Sbjct: 318 G-----STPYTLLDYFPDDFL-------IIVDESHVTL-----PQLRGMYNGDRARKQVL 360 Query: 216 ------LISAT--LPHEILEMTNKFMTDPIRILVKRDELTLEG------IKQFFVA---- 257 L SA P E K I V E ++Q Sbjct: 361 VDHGFRLPSALDNRPLTFEEFEQKINQ---IIYVSATPGPYELEHSPGVVEQIIRPTGLL 417 Query: 258 -----VEREEWKFDTLC-DLYDTLTIT-QAVIFCNTKRKVDWLTEKMREANFTVSSMHGD 310 V + + D L ++ + + + ++ TK+ + LT+ ++EA V+ +H + Sbjct: 418 DPTIDVRPTKGQIDDLIGEIRERVERNERTLVTTLTKKMAEDLTDYLKEAGIKVAYLHSE 477 Query: 311 MPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPN-----NRELYIHRI 365 + ER I+++ R G VL+ ++ GLD+P+VSL+ D + I I Sbjct: 478 IKTLERIEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTI 537 Query: 366 GRSGRYGRKGVAINFVKN---------DDIRILRDIEQYYSTQIDEMPMNV 407 GR+ R G I + + + R I++ Y+ + +P V Sbjct: 538 GRAARNAN-GHVIMYADTITKSMEIAIQETKRRRAIQEEYNRKHGIVPRTV 587 >5TNU-A nrPDB Length = 459 Score = 91.9 bits (227), Expect = 4e-19, Method: Composition-based stats. Identities = 64/414 (15%), Positives = 135/414 (32%), Gaps = 95/414 (22%) Query: 32 EEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTAT 91 +E++V + I + Q A+K +K + I +G GKT Sbjct: 66 KEIEVEENVIDSLPFPLIKDKIELRDY------QAEAVKAWLKEKRGIIVLPTGAGKTQV 119 Query: 92 FSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIR 151 V + + LI+ PT +L Q ++ + Y++ GG + + I Sbjct: 120 ALKIV------SIMKVATLIVVPTIDLITQWKE---RINKYLDFDPGIIGGGEDSLKGIT 170 Query: 152 KLDYGQHVVAGTPGRVFDMIRRRSLRTRA-IKMLVLDEADEMLNKG-------FKEQIYD 203 + Y D R+ +L+ DE + ++G F Sbjct: 171 VITY-------------DSAYTRAEELGNKFPLLIFDEVHHLPSEGYSIMAQLFASPYRL 217 Query: 204 VYRYLPPAT-------QVVLISATLPHEILEMTNKF-----------------------M 233 P +++ + E+ K+ + Sbjct: 218 GLTATPERDDGKHELYPILVGPIVYRKSVEELAGKYIAKYKIKKLYVSLTNEEKKRYDGL 277 Query: 234 TDPIRILVKRDELTLEGIKQFFVAVE-----------------------REEWKFDTLCD 270 ++ + L L+ + F V+ + K + L + Sbjct: 278 RKKLKDFLSSRGLKLQNLDDFHRLVKLAAKDKEAREALLAWHESLNIAVNSQSKIEKLRE 337 Query: 271 LYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRV 330 + + ++F + +++ F + + + ERE I+++FR G RV Sbjct: 338 ILQEYKNEKIIVFTRDTQMAYRISKT-----FLIPVVTYKTDKDEREEILQKFRDGEYRV 392 Query: 331 LISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR-YGRKGVAINFVKN 383 ++++ V+ G+DVP +L I + ++ R+GR R ++ + I V Sbjct: 393 IVASTVFDEGVDVPDATLAIVMGGYGTKRQFLQRLGRILRKKDKEALLIEIVTK 446 >2NMV-A nrPDB Length = 661 Score = 90.8 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 57/285 (20%), Positives = 105/285 (36%), Gaps = 57/285 (20%) Query: 163 TPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVV------L 216 TP + D M+V+DE+ + Q+ ++ QV+ L Sbjct: 321 TPYTLLDYFPDDF-------MIVVDESHVTI-----PQVRGMFNGDQARKQVLVDHGFRL 368 Query: 217 ISAT--LPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDT 274 SA P E K M + + V E I+ VE+ L L D Sbjct: 369 PSALDNRPLRFEEF-EKHMHN--IVYVSATPGPYE-IEHTDEMVEQIIRPTGLLDPLIDV 424 Query: 275 LTIT------------------QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKER 316 I + ++ TK+ + LT+ ++E V+ +H ++ ER Sbjct: 425 RPIEGQIDDLIGEIQARIERNERVLVTTLTKKMSEDLTDYLKEIGIKVNYLHSEIKTLER 484 Query: 317 ESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPN-----NRELYIHRIGRSGRY 371 I+++ R G VL+ ++ GLD+P+VSL+ D + I IGR+ R Sbjct: 485 IEIIRDLRLGKYDVLVGINLLREGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARN 544 Query: 372 GRKGVAINFVKN---------DDIRILRDIEQYYSTQIDEMPMNV 407 +G I + ++ + R+ ++ ++ + P + Sbjct: 545 A-EGRVIMYADKITKSMEIAINETKRRREQQERFNEEHGITPKTI 588 >2FWR-A nrPDB Length = 472 Score = 90.4 bits (223), Expect = 1e-18, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 57/122 (46%), Gaps = 6/122 (4%) Query: 260 REEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESI 319 + K L ++ + + +IF V +++ F + ++ ++ERE I Sbjct: 332 NSKNKIRKLREILERHRKDKIIIFTRHNELVYRISKV-----FLIPAITHRTSREEREEI 386 Query: 320 MKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGR-KGVAI 378 ++ FR+G R ++S+ V G+DVP ++ + + YI R+GR R + K A+ Sbjct: 387 LEGFRTGRFRAIVSSQVLDEGIDVPDANVGVIMSGSGSAREYIQRLGRILRPSKGKKEAV 446 Query: 379 NF 380 + Sbjct: 447 LY 448 >4XGT-A nrPDB Length = 993 Score = 83.1 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 62/428 (14%), Positives = 126/428 (29%), Gaps = 120/428 (28%) Query: 63 AIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQI 122 Q ++ I + V+ + + GKT ++ QCL + + + +P + L+ Q Sbjct: 70 PFQALSVASIEREESVLVSAHTSAGKTVVAEYAIAQCLK---KNQRVIYTSPIKALSNQK 126 Query: 123 QKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIK 182 + A + + ++ + T + M+ R S R + Sbjct: 127 YRDFQAEFGDVGLMTGDVT-----------INPTASCLVMTTEILRSMLYRGSEIMREVA 175 Query: 183 MLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEIL--------------EM 228 +V DE M +K + LP + V +SAT+P+ + Sbjct: 176 WVVFDEIHYMRDKIRGVVWEETIILLPDKVRYVFLSATIPNAFQFAEWIAKIHRQACHVV 235 Query: 229 TNKFMTDPIR-------------ILVKRDELTLEGIKQFFVAVER--------------- 260 F P++ I+ ++ Q +E Sbjct: 236 YTDFRPTPLQNYFFPAGGKGILLIVDEKGNFKENNFNQAMAMIEEKKGTDSNDWSAKQKG 295 Query: 261 ---------------EEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTV- 304 E+ + + ++F +KR+ + + F Sbjct: 296 KGKNKKTNKGGEAADEKADIAKIIKMILKKNFQPVIVFNFSKRECEQMALASSSMKFNAP 355 Query: 305 --------------------------------------SSMHGDMPQKERESIMKEFRSG 326 H + +E+I F+ G Sbjct: 356 DEENMVNKVFENALASLSEDDKNLPQISNILPLLRKGIGVHHSGLLPILKETIEILFQEG 415 Query: 327 ASRVLISTDVWARGLDVPQVSLII--------NYDLPNNRELYIHRIGRSGRYGR--KGV 376 +VL +T+ ++ GL++P +++ P YI GR+GR G +G+ Sbjct: 416 LIKVLFATETFSIGLNMPARTVVFTQVTKWDGQQRRPLTSSEYIQMAGRAGRRGLDDRGI 475 Query: 377 AINFVKND 384 I V + Sbjct: 476 VIMMVDDK 483 >3P4X-A nrPDB Length = 413 Score = 80.0 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 66/332 (19%), Positives = 120/332 (36%), Gaps = 50/332 (15%) Query: 72 IIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGD 131 I++G+ + +G GKT TF ++ L + + ++ ++ PT L Q + L L D Sbjct: 32 IVQGKSFTMVAPTGVGKT-TFG--MMTALWLARKGKKSALVFPTVTLVKQTLERLQKLAD 88 Query: 132 YMNVQCHACIGGTNVGEDIRKLDYGQ----HVVA-----GTPGRVFDMIRRRSLRTRAIK 182 V+ E + + H++ + R +R Sbjct: 89 E-KVKIFGFYSSMKKEEKEKFEKSFEEDDYHILVFSTQFVSKNREKLSQKRFDFVFVDDV 147 Query: 183 MLVLDEA---DEMLNK-GFKEQIY----------DVYRYLPPATQ--VVLISATL-PHEI 225 VL + D +L G E+I +Y +V+ SAT P I Sbjct: 148 DAVLKASRNIDTLLMMVGIPEEIIRKAFSTIKQGKIYERPKNLKPGILVVSSATAKPRGI 207 Query: 226 LEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCN 285 + + + + V R I ++ +E L +L + + +IF Sbjct: 208 RPLLFRDLLN---FTVGRLVSVARNITHVRISSRSKE----KLVELLE-IFRDGILIFAQ 259 Query: 286 TKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDV----WARGL 341 T+ + L E ++ F V E E ++F+ G +LI RG+ Sbjct: 260 TEEEGKELYEYLKRFKFNVGE-----TWSEFEKNFEDFKVGKINILIGVQAYYGKLTRGV 314 Query: 342 DVPQ-VSLIINYDLPNNRE--LYIHRIGRSGR 370 D+P+ + +I + P+ + YI GRS R Sbjct: 315 DLPERIKYVIFWGTPSGPDVYTYIQASGRSSR 346 >3TBK-A nrPDB Length = 555 Score = 78.1 bits (191), Expect = 7e-15, Method: Composition-based stats. Identities = 44/201 (21%), Positives = 76/201 (37%), Gaps = 28/201 (13%) Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT 278 A E+T +F + + + E K + L + Y T Sbjct: 339 AAFDETERELTRRFEEKLEELEKVSRDPSNENPKL--------RDLYLVLQEEYHLKPET 390 Query: 279 QAVIFCNTKRKVDWLTEKMREAN----FTVSSMHG--------DMPQKERESIMKEFR-S 325 + ++F T+ VD L + + E + G M ++ +++ FR S Sbjct: 391 KTILFVKTRALVDALKKWIEENPALSFLKPGILTGRGRTNRATGMTLPAQKCVLEAFRAS 450 Query: 326 GASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDD 385 G + +LI+T V G+D+ + +L+I Y+ N I GR GR R + D Sbjct: 451 GDNNILIATSVADEGIDIAECNLVILYEYVGNVIKMIQTRGR-GRA-RDSKCFLLTSSAD 508 Query: 386 IRILRDIEQYYSTQIDEMPMN 406 + IE+ + I E MN Sbjct: 509 V-----IEKEKANMIKEKIMN 524 Score = 66.1 bits (160), Expect = 3e-11, Method: Composition-based stats. Identities = 34/251 (13%), Positives = 83/251 (33%), Gaps = 10/251 (3%) Query: 60 KPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD--IQVRETQALILAPTRE 117 KP Q KG++ I + +G GKT + L ++ + + A Sbjct: 4 KPRNYQLELALPAKKGKNTIICAPTGCGKTFVSLLICEHHLKKFPCGQKGKVVFFANQIP 63 Query: 118 LAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSL- 176 + Q + + + G T+ ++ + ++ TP + + + ++ Sbjct: 64 VYEQQATVFSRYFERLGYNIASISGATSDSVSVQHIIEDNDIIILTPQILVNNLNNGAIP 123 Query: 177 RTRAIKMLVLDEADEMLNKGFKEQIY------DVYRYLPPATQVVLISATLPHEILEMTN 230 +++ DE QI + P QVV ++A++ + Sbjct: 124 SLSVFTLMIFDECHNTSKNHPYNQIMFRYLDHKLGESRDPLPQVVGLTASVGVGDAKTAE 183 Query: 231 KFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQ-AVIFCNTKRK 289 + M ++ D + ++ +E+ +K + + T I ++ Sbjct: 184 EAMQHICKLCAALDASVIATVRDNVAELEQVVYKPQKISRKVASRTSNTFKCIISQLMKE 243 Query: 290 VDWLTEKMREA 300 + L + + E Sbjct: 244 TEKLAKDVSEE 254 >1C4O-A nrPDB Length = 664 Score = 76.5 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 28/127 (22%), Positives = 55/127 (43%), Gaps = 6/127 (4%) Query: 278 TQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVW 337 + ++ T R + LT + E +H ++ +R++++++ R G L+ ++ Sbjct: 440 ERTLVTVLTVRMAEELTSFLVEHGIRARYLHHELDAFKRQALIRDLRLGHYDCLVGINLL 499 Query: 338 ARGLDVPQVSLIINYDLPN-----NRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392 GLD+P+VSL+ D + I IGR+ R R G + + R I Sbjct: 500 REGLDIPEVSLVAILDADKEGFLRSERSLIQTIGRAARNAR-GEVWLYADRVSEAMQRAI 558 Query: 393 EQYYSTQ 399 E+ + Sbjct: 559 EETNRRR 565 Score = 36.1 bits (82), Expect = 0.028, Method: Composition-based stats. Identities = 23/85 (27%), Positives = 36/85 (42%), Gaps = 13/85 (15%) Query: 55 AYGFEKPSAI--QQRAIKQIIKG-RD----VIAQSQSGTGKTATFSISVLQCLDIQVRET 107 + + PS Q +AI +++ RD V +GTGKT T + + + Sbjct: 1 TFRYRGPSPKGDQPKAIAGLVEALRDGERFVTLLGATGTGKTVT-----MAKVIEALGRP 55 Query: 108 QALILAPTRELAVQIQKGLLALGDY 132 AL+LAP + LA Q+ L Sbjct: 56 -ALVLAPNKILAAQLAAEFRELFPE 79 >6DCR-A nrPDB Length = 694 Score = 75.0 bits (183), Expect = 6e-14, Method: Composition-based stats. Identities = 70/420 (16%), Positives = 139/420 (33%), Gaps = 105/420 (25%) Query: 65 QQRAIKQIIKGRDV----IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 Q A+ I D + +G+GKT + +SVL+ + Q + QAL++ P L Sbjct: 165 QATAVGAIHSAADTFSAWLLAGVTGSGKTEVY-LSVLENVLAQGK--QALVMVPEIGLTP 221 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGED----IRKLDYGQHVVAGTPGRVFDMIRRRSL 176 Q + + N G N E ++ + +V GT +F Sbjct: 222 QT---IARFRERFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGTRSALF-------T 271 Query: 177 RTRAIKMLVLDEADEML---NKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFM 233 + + ++V+DE + +G++ D+ Y + Q+ +I + + + N Sbjct: 272 PFKNLGVIVIDEEHDSSYKQQEGWRYHARDLAVYRAHSEQIPIILGSATPALETLCNVQQ 331 Query: 234 TDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT-----ITQAVIFCNTK- 287 + + R Q + ++ ++ + L + Q ++F N + Sbjct: 332 KKYRLLRLTRRAGNARPAIQHVLDLKGQKVQAGLAPALITRMRQHLQADNQVILFLNRRG 391 Query: 288 -------RKVDWLTE--------KMREANFTVSSMHGD---------------------- 310 W+ E + +A + H D Sbjct: 392 FAPALLCHDCGWIAECPRCDHYYTLHQAQHHLRCHHCDSQRPVPRQCPSCGSTHLVPVGL 451 Query: 311 -MPQKER-------------------------ESIMKEFRSGASRVLISTDVWARGLDVP 344 Q E+ E + E G +R+LI T + A+G P Sbjct: 452 GTEQLEQTLAPLFPGVPISRIDRDTTSRKGALEQQLAEVHRGGARILIGTQMLAKGHHFP 511 Query: 345 QVSLIINYDL------------PNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDI 392 V+L+ D+ +LY GR+GR G++G + + + +L+ + Sbjct: 512 DVTLVALLDVDGALFSADFRSAERFAQLYTQVAGRAGRAGKQGEVVLQTHHPEHPLLQTL 571 >4BPB-A nrPDB Length = 698 Score = 74.6 bits (182), Expect = 7e-14, Method: Composition-based stats. Identities = 61/337 (18%), Positives = 111/337 (32%), Gaps = 54/337 (16%) Query: 98 QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ 157 + + + A ++ T LA +I K L L N + GT E Sbjct: 236 SRISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREF-----GTQKYEQWIVTVQKA 290 Query: 158 HVVAGTP-----GRVFDMIRRRSLRTRAI-KMLVLDEADEMLNKGFKEQIYDVYRYLPPA 211 +V P R+ + + R L++ E M + D + Sbjct: 291 CMVFQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARM------KDALDYLKDFFSN 344 Query: 212 TQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC-- 269 + +A ++T +F E L+ ++ E K + LC Sbjct: 345 VR----AAGFDEIEQDLTQRF------------EEKLQELESVSRDPSNENPKLEDLCFI 388 Query: 270 --DLYDTLTITQAVIFCNTKRKVD----WLTEKMREANFTVSSMHGDMPQKE-------- 315 + Y T ++F T+ VD W+ + + + G + Sbjct: 389 LQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTFFGMTL 448 Query: 316 --RESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYG 372 ++ I+ F+ SG +LI+T V G+D+ Q +L+I Y+ N I GR GR Sbjct: 449 PAQKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR-GRA- 506 Query: 373 RKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVAD 409 R N + I Y +++ + + Sbjct: 507 RGSKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQT 543 Score = 74.2 bits (181), Expect = 1e-13, Method: Composition-based stats. Identities = 37/251 (14%), Positives = 91/251 (36%), Gaps = 16/251 (6%) Query: 60 KPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD--IQVRETQALILAPTRE 117 KP Q +KG++ I + +G GKT + L Q ++ + + A Sbjct: 13 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIP 72 Query: 118 LAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSL- 176 + Q + + + G T + ++ ++ TP + + +++ ++ Sbjct: 73 VYEQNKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIP 132 Query: 177 RTRAIKMLVLDEAD--------EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEM 228 +++ DE M+ + +Q + P QV+ ++A++ + Sbjct: 133 SLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQ--KLGGSSGPLPQVIGLTASVGVGDAKT 190 Query: 229 TNKFMTDPIRILVKR-DELTLEGIKQFFVAVEREEWKFDTLCDLYD-TLTITQAVIFCNT 286 T++ + D I L D + +K +E+ +K + ++ I Sbjct: 191 TDEAL-DYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQL 249 Query: 287 KRKVDWLTEKM 297 R + L +++ Sbjct: 250 MRDTESLAKRI 260 >4ON9-A nrPDB Length = 580 Score = 74.2 bits (181), Expect = 9e-14, Method: Composition-based stats. Identities = 61/335 (18%), Positives = 111/335 (33%), Gaps = 52/335 (15%) Query: 98 QCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQ 157 + + + A ++ T LA +I K L L N + GT E Sbjct: 252 SRISDKFKYIIAQLMRDTESLAKRICKDLENLSQIQNREF-----GTQKYEQWIVTVQKA 306 Query: 158 HVVAGTP-----GRVFDMIRRRSLRTRAI-KMLVLDEADEMLNKGFKEQIYDVYRYLPPA 211 +V P R+ + + R L++ E M + D + Sbjct: 307 CMVFQMPDKDEESRICKALFLYTSHLRKYNDALIISEHARM------KDALDYLKDFFSN 360 Query: 212 TQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLC-- 269 + +A ++T +F E L+ ++ E K + LC Sbjct: 361 VR----AAGFDEIEQDLTQRF------------EEKLQELESVSRDPSNENPKLEDLCFI 404 Query: 270 --DLYDTLTITQAVIFCNTKRKVD----WLTEKMREANFTVSSMHGDMPQKE-------- 315 + Y T ++F T+ VD W+ + + + G + Sbjct: 405 LQEEYHLNPETITILFVKTRALVDALKNWIEGNPKLSFLKPGILTGRGKTNQNTGMTLPA 464 Query: 316 RESIMKEFR-SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRK 374 ++ I+ F+ SG +LI+T V G+D+ Q +L+I Y+ N I GR GR R Sbjct: 465 QKCILDAFKASGDHNILIATSVADEGIDIAQCNLVILYEYVGNVIKMIQTRGR-GRA-RG 522 Query: 375 GVAINFVKNDDIRILRDIEQYYSTQIDEMPMNVAD 409 N + I Y +++ + + Sbjct: 523 SKCFLLTSNAGVIEKEQINMYKEKMMNDSILRLQT 557 Score = 73.8 bits (180), Expect = 1e-13, Method: Composition-based stats. Identities = 37/251 (14%), Positives = 91/251 (36%), Gaps = 16/251 (6%) Query: 60 KPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD--IQVRETQALILAPTRE 117 KP Q +KG++ I + +G GKT + L Q ++ + + A Sbjct: 29 KPRNYQLELALPAMKGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFANQIP 88 Query: 118 LAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSL- 176 + Q + + + G T + ++ ++ TP + + +++ ++ Sbjct: 89 VYEQQKSVFSKYFERHGYRVTGISGATAENVPVEQIVENNDIIILTPQILVNNLKKGTIP 148 Query: 177 RTRAIKMLVLDEAD--------EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEM 228 +++ DE M+ + +Q + P QV+ ++A++ + Sbjct: 149 SLSIFTLMIFDECHNTSKQHPYNMIMFNYLDQ--KLGGSSGPLPQVIGLTASVGVGDAKN 206 Query: 229 TNKFMTDPIRILVKR-DELTLEGIKQFFVAVEREEWKFDTLCDLYD-TLTITQAVIFCNT 286 T++ + D I L D + +K +E+ +K + ++ I Sbjct: 207 TDEAL-DYICKLCASLDASVIATVKHNLEELEQVVYKPQKFFRKVESRISDKFKYIIAQL 265 Query: 287 KRKVDWLTEKM 297 R + L +++ Sbjct: 266 MRDTESLAKRI 276 >5VHD-D nrPDB Length = 870 Score = 73.4 bits (179), Expect = 2e-13, Method: Composition-based stats. Identities = 75/483 (15%), Positives = 158/483 (32%), Gaps = 112/483 (23%) Query: 32 EEVDVTPTFD-----TMGLREDLLRGIYAYGFEKPSA---IQQRAIKQIIKGRDVIAQSQ 83 +E + T D + ++ LR I F + +Q+ + I + + + Sbjct: 25 QENEPDATLDQQLLEDLQKKKTDLRYIEMQRFREKLPSYGMQKELVNMIDNHQVTVISGE 84 Query: 84 SGTGKTATFSISVLQCLDIQVRETQALILA--PTRELAVQIQKGLLALGDYMNVQCHACI 141 +G GKT + +L + + + I+ P R A+ + + + A + +C Sbjct: 85 TGCGKTTQVTQFILDNYIERGKGSACRIVCTQPRRISAISVAERVAAE------RAESCG 138 Query: 142 GGTNVGEDIR---KL-DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEAD-EMLNKG 196 G + G IR +L ++ T G + ++ ++ +VLDE L Sbjct: 139 NGNSTGYQIRLQSRLPRKQGSILYCTTGIILQWLQSDP-HLSSVSHIVLDEIHERNLQSD 197 Query: 197 FKEQIYDVYRYLPPATQVVLISATLP--------------------------------HE 224 + P +VVL+SATL + Sbjct: 198 VLMTVVKDLLSYRPDLKVVLMSATLNAEKFSEYFGNCPMIHIPGFTFPVVEYLLEDIIEK 257 Query: 225 IL----------EMTNKFMTD---------PIRILVKRDELTLEGIKQFF--------VA 257 I + FM I +R L ++Q + Sbjct: 258 IRYVPEQKEHRSQFKKGFMQGHVNRQEKYYYEAIYKERWPGYLRELRQRYSASTVDVVEM 317 Query: 258 VEREEWKFDTLCDLYDTL----TITQAVIFCNTKRKVDWLTEKM------REANFTVSSM 307 ++ E+ + + L + ++F + L + + + F + + Sbjct: 318 MDDEKVDLNLIAALIRYIVLEEEDGAILVFLPGWDNISTLHDLLMSQVMFKSDKFIIIPL 377 Query: 308 HGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII--------NYDLPNNRE 359 H MP + + K G +++I+T++ + + V +I ++D NN Sbjct: 378 HSLMPTVNQTQVFKRTPPGVRKIVIATNIAETSITIDDVVYVIDGGKIKETHFDTQNNIS 437 Query: 360 LY----------IHRIGRSGRYGRKGVAINFVKNDDIRILRDIE--QYYSTQIDEMPMNV 407 R GR+GR + G + + +L D + + T ++E+ + + Sbjct: 438 TMSAEWVSKANAKQRKGRAGRV-QPGHCYHLYNSLRASLLDDYQLPEILRTPLEELCLQI 496 Query: 408 ADL 410 L Sbjct: 497 KIL 499 >6F4A-B nrPDB Length = 644 Score = 72.3 bits (176), Expect = 3e-13, Method: Composition-based stats. Identities = 68/368 (18%), Positives = 136/368 (36%), Gaps = 57/368 (15%) Query: 51 RGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQAL 110 +++ F P+ A + I+ ++ + +GKT LQ L R A Sbjct: 137 DSVHSVDFSNPAEWFPEA--RKIRRHIIMHVGPTNSGKTFR----SLQKLKAADRGYYA- 189 Query: 111 ILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDM 170 P R LA ++ + + NV+C+ G E I+ LD + T G + + Sbjct: 190 --GPLRLLAREVYEK----FKHENVRCNLLTG----EEVIKDLDEMGNEANLTSGTIEMI 239 Query: 171 IRRRSLRTRAIKMLVLDEADEM--LNKGFKEQIYDVYRYLPPATQVVLISATLP--HEIL 226 ++ ++VLDE M L++G+ + ++T+P +I+ Sbjct: 240 PLNQNFD-----VVVLDEIQMMADLDRGWAWT-NALLGAKAKEVHCCGEASTIPLIKKIV 293 Query: 227 EMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNT 286 EMT +T E + + VE E L Y +L V+ + Sbjct: 294 EMTGDKLT------------INEYERMGKLVVEEE-----ALTKGYHSLKKGDCVVAFSK 336 Query: 287 KRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQV 346 K +D E ++ + ++G +P + R F SG +LI++D GL++ Sbjct: 337 KAILDLKLEIEKKTELKAAVIYGSLPPETRVKQANLFNSGEFDILIASDAIGMGLNLSID 396 Query: 347 SLIINYDLPNNRELYIHRI--------GRSGRY-----GRKGVAINFVKNDDIRILRDIE 393 ++ + + GR+GR+ + + ++ +L+ + Sbjct: 397 RVVFTTSKKFDGRDMVDMTSSAIKQIGGRAGRFKQNIHDNGELPVGYITAVKPNVLKAVR 456 Query: 394 QYYSTQID 401 + + I+ Sbjct: 457 EAINAPIE 464 >4NL8-A nrPDB Length = 747 Score = 70.0 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 72/422 (17%), Positives = 138/422 (32%), Gaps = 109/422 (25%) Query: 65 QQRAIKQIIKGRD----VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 Q A+ I D + +G+GKT + +SVL+ + Q R QAL++ P L Sbjct: 218 QATAVGAIHSAADRFSAWLLAGITGSGKTEVY-LSVLENVLAQGR--QALVMVPEIGLTP 274 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGED----IRKLDYGQHVVAGTPGRVFDMIRRRSL 176 Q + N G N E ++ + +V GT +F Sbjct: 275 QT---IARFRQRFNAPVEVLHSGLNDSERLSAWLKAKNGEAAIVIGTRSSLF-------T 324 Query: 177 RTRAIKMLVLDEADEML---NKGFKEQIYDVY--RYLPPATQVVLISATLPHEILEMTNK 231 + + ++V+DE + +G++ D+ R ++L SAT + + N Sbjct: 325 PFKDLGVIVIDEEHDSSYKQQEGWRYHARDLAVWRAHSEQIPIILGSAT--PALETLHNV 382 Query: 232 FMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT-----ITQAVIFCNT 286 ++ + + +Q + ++ + + L + Q ++F N Sbjct: 383 RQGKYRQLTLSKRAGNARPAQQHVLDLKGQPLQAGLSPALISRMRQHLQADNQVILFLNR 442 Query: 287 K--------RKVDWLTE--------KMREANFTVSSMHGD-------------------- 310 + W+ E + +A + H D Sbjct: 443 RGFAPALLCHDCGWIAECPRCDSYYTLHQAQHHLRCHHCDSQRPIPRQCPSCGSTHLVPV 502 Query: 311 ---MPQKER-------------------------ESIMKEFRSGASRVLISTDVWARGLD 342 Q E+ E + G +R+LI T + A+G Sbjct: 503 GIGTEQLEQALAPLFPEVPISRIDRDTTSRKGALEEHLAAVHRGGARILIGTQMLAKGHH 562 Query: 343 VPQVSLIINYDL------------PNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILR 390 P V+L+ D+ +LY GR+GR G++G I + + +L+ Sbjct: 563 FPDVTLVSLLDVDGALFSADFRSAERFAQLYTQVSGRAGRAGKQGEVILQTHHPEHPLLQ 622 Query: 391 DI 392 + Sbjct: 623 TL 624 >5WX1-A nrPDB Length = 733 Score = 68.8 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 44/314 (14%), Positives = 107/314 (34%), Gaps = 59/314 (18%) Query: 84 SGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGG 143 +G GKT + ++ R + L+L P R A + + + + ++ + IG Sbjct: 278 TGAGKTT--ELPR-SVIEEIGRHKRVLVLIPLRAAAESVYQYMRQ--KHPSIAFNLRIG- 331 Query: 144 TNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKM--LVLDEADEMLNKGFKEQI 201 ++++ D + + G M + LR ++ + LDE + Sbjct: 332 -----EMKEGDMATGITYASYGYFCQM-PQPKLRAAMVEYSFIFLDEYHCA-----TPEQ 380 Query: 202 YDVYRYLPP---ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAV 258 + + +VV ++AT + K PI + + + E + ++ + Sbjct: 381 LAIMGKIHRFSENLRVVAMTATPAGTVTTTGQKH---PIEEFIAPEVMKGEDLGSEYLDI 437 Query: 259 EREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERES 318 + + + ++F T+ +K++ + + E S Sbjct: 438 AGLKIPVEEMKSNM--------LVFVPTRNMAVETAKKLKAKGYNSGYYYSG----EDPS 485 Query: 319 IMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRE------------------- 359 ++ S + V+++T+ G+ +P + ++++ L + Sbjct: 486 NLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSSKMPFIVTGLKRMAV 545 Query: 360 ---LYIHRIGRSGR 370 R GR GR Sbjct: 546 TIGEQAQRRGRVGR 559 >6HEG-A nrPDB Length = 809 Score = 68.4 bits (166), Expect = 5e-12, Method: Composition-based stats. Identities = 52/376 (13%), Positives = 137/376 (36%), Gaps = 52/376 (13%) Query: 66 QRAIKQIIKGRDV----IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQ 121 + +++ D + + +G GK+ + LQ L + ++L P R A Sbjct: 7 AAVLPELLTALDCAPQVLLSAPTGAGKST--WLP-LQLLAHPGINGKIILLEPRRLAARN 63 Query: 122 IQKGLLAL-GDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 + + L L + + N +L+ T G + MI+R Sbjct: 64 VAQRLAELLNEKPGDTVGYRMRAQNCVGPNTRLE------VVTEGVLTRMIQRDP-ELSG 116 Query: 181 IKMLVLDEADE--MLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIR 238 + +++LDE E + + DV + L +++++SATL ++ L+ P Sbjct: 117 VGLVILDEFHERSLQADLALALLLDVQQGLRDDLKLLIMSATLDNDRLQQML-----PEA 171 Query: 239 ILVKRDELTLEGIKQFFVAV---EREEWKFDTLCDLYDTLTITQAVIFCN----TKRKVD 291 +V + + +++ ++ + +R + ++F +R + Sbjct: 172 PVVISEGRSFP-VERRYLPLPAHQRFDDAVAVATAEMLRQESGSLLLFLPGVGEIQRVQE 230 Query: 292 WLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII- 350 L ++ ++G + ++ + G +V+++T++ L + + L++ Sbjct: 231 QLASRIGSDVLLCP-LYGALSLNDQRKAILPAPQGMRKVVLATNIAETSLTIEGIRLVVD 289 Query: 351 -------NYDLPN----------NRELYIHRIGRSGRYGRKGVAINFVKND--DIRILRD 391 +D ++ R GR+GR G++++ + + + + Sbjct: 290 CAQERVARFDPRTGLTRLITQRVSQASMTQRAGRAGRL-EPGISLHLIAKEQAERAAAQS 348 Query: 392 IEQYYSTQIDEMPMNV 407 + + + + M + Sbjct: 349 EPEILQSDLSGLLMEL 364 >4CBI-A nrPDB Length = 516 Score = 66.9 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 44/314 (14%), Positives = 107/314 (34%), Gaps = 59/314 (18%) Query: 84 SGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGG 143 +G GKT + ++ R + L+L P R A + + + + ++ + IG Sbjct: 53 TGAGKTT--ELPR-SVIEEIGRHKRVLVLIPLRAAAESVYQYMRQ--KHPSIAFNLRIG- 106 Query: 144 TNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKM--LVLDEADEMLNKGFKEQI 201 ++++ D + + G M + LR ++ + LDE + Sbjct: 107 -----EMKEGDMATGITYASYGYFCQM-SQPKLRAAMVEYSFIFLDEYHCA-----TPEQ 155 Query: 202 YDVYRYLPP---ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAV 258 + + +VV ++AT + K PI + + + E + ++ + Sbjct: 156 LAIMGKIHRFSENLRVVAMTATPAGTVTTTGQKH---PIEEFIAPEVMKGEDLGSEYLDI 212 Query: 259 EREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERES 318 + + + ++F T+ +K++ + + E S Sbjct: 213 AGLKIPVEEMK--------NNMLVFVPTRNMAVEAAKKLKAKGYNSGYYYSG----EDPS 260 Query: 319 IMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRE------------------- 359 ++ S + V+++T+ G+ +P + ++++ L + Sbjct: 261 NLRVVTSQSPYVVVATNAIESGVTLPDLDVVVDTGLKCEKRIRLSPKMPFIVTGLKRMAV 320 Query: 360 ---LYIHRIGRSGR 370 R GR GR Sbjct: 321 TIGEQAQRRGRVGR 334 >4A4Z-A nrPDB Length = 997 Score = 65.7 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 39/211 (18%), Positives = 82/211 (38%), Gaps = 25/211 (11%) Query: 19 KEEDMTKVEFETSEEVDV---TPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKG 75 + M V+ E + VD+ FD + ++ FE + Q+ A+ + +G Sbjct: 1 GPDSMVPVKKEWAHVVDLNHKIENFDELIPNPA-----RSWPFELDT-FQKEAVYHLEQG 54 Query: 76 RDVIAQSQSGTGKTAT--FSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYM 133 V + + GKT ++I++ T+ + +P + L+ Q + D Sbjct: 55 DSVFVAAHTSAGKTVVAEYAIAMAHR-----NMTKTIYTSPIKALSNQKFRDFKETFD-- 107 Query: 134 NVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEML 193 +V G + D L + + M+ R + R ++ ++ DE + Sbjct: 108 DVNIGLITGDVQINPDANCLIMTTEI-------LRSMLYRGADLIRDVEFVIFDEVHYVN 160 Query: 194 NKGFKEQIYDVYRYLPPATQVVLISATLPHE 224 ++ +V LP + +L+SAT+P+ Sbjct: 161 DQDRGVVWEEVIIMLPQHVKFILLSATVPNT 191 Score = 53.0 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 29/205 (14%), Positives = 62/205 (30%), Gaps = 53/205 (25%) Query: 250 GIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANF------- 302 ++FF + + + + + V+F +K++ + + + NF Sbjct: 309 NKRKFFTQDGPSKKTWPEIVNYLRKRELLPMVVFVFSKKRCEEYADWLEGINFCNNKEKS 368 Query: 303 --------------------------------TVSSMHGDMPQKERESIMKEFRSGASRV 330 ++ HG + +E I F G +V Sbjct: 369 QIHMFIEKSITRLKKEDRDLPQILKTRSLLERGIAVHHGGLLPIVKELIEILFSKGFIKV 428 Query: 331 LISTDVWARGLDVPQVSLIINYDLPN---------NRELYIHRIGRSGRYGRKGVAINFV 381 L +T+ +A GL++P +I + + GR+GR G V Sbjct: 429 LFATETFAMGLNLPT-RTVIFSSIRKHDGNGLRELTPGEFTQMAGRAGRRGLDSTGTVIV 487 Query: 382 ----KNDDIRILRDIEQYYSTQIDE 402 I +++ T++ Sbjct: 488 MAYNSPLSIATFKEVTMGVPTRLQS 512 >2OCA-A nrPDB Length = 510 Score = 64.6 bits (156), Expect = 7e-11, Method: Composition-based stats. Identities = 58/355 (16%), Positives = 123/355 (34%), Gaps = 43/355 (12%) Query: 65 QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQK 124 Q+ A+ + + R I + G++ ++ L ++ E + LI+ PT L Q+ Sbjct: 118 QKDAVFEGLVNRRRILNLPTSAGRSLIQAL--LARYYLENYEGKILIIVPTTALTTQMAD 175 Query: 125 GLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKML 184 + + + GG + + K VV GT V +++ M+ Sbjct: 176 DFVDYRLFSHAMIKKIGGGASKDD---KYKNDAPVVVGTWQTV---VKQPKEWFSQFGMM 229 Query: 185 VLDEAD----------------EMLNKGFKEQIYDVYRYLPPATQVVLI---------SA 219 + DE M G + D + V + S Sbjct: 230 MNDECHLATGKSISSIISGLNNCMFKFGLSGSLRDGKANIM--QYVGMFGEIFKPVTTSK 287 Query: 220 TLPH---EILEMTNKFMTDPIRILVKRDELTL-EGIKQFFVAVEREEWKFDTLCDLYDTL 275 + L++ + F+ P K T E IK +R +W L Sbjct: 288 LMEDGQVTELKINSIFLRYPDEFTTKLKGKTYQEEIKIITGLSKRNKW-IAKLAIKLAQK 346 Query: 276 TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST- 334 V+F + + + ++ V + G++ + R + +G +++++ Sbjct: 347 DENAFVMFKHVSHG-KAIFDLIKNEYDKVYYVSGEVDTETRNIMKTLAENGKGIIIVASY 405 Query: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGR-YGRKGVAINFVKNDDIRI 388 V++ G+ V + ++ ++ + + IGR R +G K +A + DD + Sbjct: 406 GVFSTGISVKNLHHVVLAHGVKSKIIVLQTIGRVLRKHGSKTIATVWDLIDDAGV 460 >5WSO-A nrPDB Length = 476 Score = 64.2 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 49/314 (15%), Positives = 114/314 (36%), Gaps = 59/314 (18%) Query: 84 SGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGG 143 +G GKT +V++ + R + L+L P R A + + + + ++ + IG Sbjct: 21 TGAGKTTELPKAVIEEI---GRHKRVLVLIPLRAAAESVYQYMR--LKHPSISFNLRIG- 74 Query: 144 TNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKM--LVLDEADEMLNKGFKEQI 201 D+++ D + + G M + LR ++ + LDE + Sbjct: 75 -----DMKEGDMATGITYASYGYFCQM-PQPKLRAAMVEYSYIFLDEYHCA-----TPEQ 123 Query: 202 YDVYRYLPP---ATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAV 258 + + + +VV ++AT + K PI + + + E + F+ + Sbjct: 124 LAIIGKIHRFSESIRVVAMTATPAGSVTTTGQKH---PIEEFIAPEVMKGEDLGSQFLDI 180 Query: 259 EREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERES 318 + D + ++F T+ + +K++ + + E + Sbjct: 181 AGLKIPVDEMKGNM--------LVFVPTRNMAVEVAKKLKAKGYNSGYYYSG----EDPA 228 Query: 319 IMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDL-------PNNRELYI--------- 362 ++ S + V+++T+ G+ +P + +I+ L +++ +I Sbjct: 229 NLRVVTSQSPYVIVATNAIESGVTLPDLDTVIDTGLKCEKRVRVSSKIPFIVTGLKRMAV 288 Query: 363 ------HRIGRSGR 370 R GR GR Sbjct: 289 TVGEQAQRRGRVGR 302 >5I8Q-A nrPDB Length = 767 Score = 63.0 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 56/352 (15%), Positives = 125/352 (35%), Gaps = 65/352 (18%) Query: 78 VIAQSQSGTGKTATFSISVLQCLD--IQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 ++ ++G+GKT I D + TQ P R A+ + + M+V Sbjct: 112 MVFVGETGSGKTT--QIPQFVLFDEMPHLENTQVACTQPRRVAAM---SVAQRVAEEMDV 166 Query: 136 QCHACIGGTNVGEDIRKLDYGQHVV-AGTPGRVFDMIRRRSLRTRAIKMLVLDEADEM-- 192 + +G + ++ T G + ++LDEA E Sbjct: 167 KLGEEVG---YSIRFENKTSNKTILKYMTDGMLLREAMEDH-DLSRYSCIILDEAHERTL 222 Query: 193 ---LNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLE 249 + G +Q+ P +++++SATL + + F P+ + R T Sbjct: 223 ATDILMGLLKQVVK----RRPDLKIIIMSATL--DAEKFQRYFNDAPLLAVPGR---TYP 273 Query: 250 GIKQFFVAVEREEW---KFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREAN----- 301 ++ ++ + ++ T+ ++ T ++F + +++ K+ Sbjct: 274 -VELYYTPEFQRDYLDSAIRTVLQIHATEEAGDILLFLTGEDEIEDAVRKISLEGDQLVR 332 Query: 302 ------FTVSSMHGDMPQKERESIMK---EFRSGA--SRVLISTDVWARGLDVPQVSLII 350 +V ++G +P +++ I + E +G +V+IST++ L + + ++ Sbjct: 333 EEGCGPLSVYPLYGSLPPHQQQRIFEPAPESHNGRPGRKVVISTNIAETSLTIDGIVYVV 392 Query: 351 --------NYDL----------PNNRELYIHRIGRSGRYGRKGVAINFVKND 384 Y+ P ++ R GR+GR R G + Sbjct: 393 DPGFSKQKVYNPRIRVESLLVSPISKASAQQRAGRAGR-TRPGKCFRLYTEE 443 >5GM6-Y nrPDB Length = 876 Score = 62.7 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 62/361 (17%), Positives = 122/361 (33%), Gaps = 54/361 (14%) Query: 78 VIAQSQSGTGKTATFSIS--VLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNV 135 +I ++G+GKT + +++ + Q I P R A + + D MNV Sbjct: 242 LIIMGETGSGKTT--QLPQYLVEDGFTDQGKLQIAITQPRRVAATSVAARV---ADEMNV 296 Query: 136 QCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEAD-EMLN 194 +G ED + + T G + S + +++DEA L Sbjct: 297 VLGKEVGYQIRFEDKTTPNKTV-LKYMTDGMLLREFLTDS-KLSKYSCIMIDEAHERTLA 354 Query: 195 KGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKR----------- 243 + P ++++ SAT+ + + F PI + R Sbjct: 355 TDILIGLLKDILPQRPTLKLLISSATMN--AKKFSEFFDNCPIFNVPGRRYPVDIHYTLQ 412 Query: 244 --DELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKM--RE 299 I F + D L L I + TK K++ + K+ R Sbjct: 413 PEANYIHAAITTIFQIHTTQSLPGDILVFLTGQEEIER------TKTKLEEIMSKLGSRT 466 Query: 300 ANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN-------- 351 ++ ++ ++PQ+++ I + +V+++T++ L + + +I+ Sbjct: 467 KQMIITPIYANLPQEQQLKIFQPTPENCRKVVLATNIAETSLTIDGIRYVIDPGFVKENS 526 Query: 352 ----------YDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQYYSTQID 401 +P +R R GR+GR G G L ++E +I Sbjct: 527 YVPSTGMTQLLTVPCSRASVDQRAGRAGRVG-PGKCFRIFTK--WSYLHELELMPKPEIT 583 Query: 402 E 402 Sbjct: 584 R 584 >5D0U-A nrPDB Length = 714 Score = 62.7 bits (151), Expect = 3e-10, Method: Composition-based stats. Identities = 51/354 (14%), Positives = 119/354 (33%), Gaps = 67/354 (18%) Query: 78 VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILA--PTR----ELAVQIQKGL-LALG 130 ++ ++G+GKT I D +T LI P R +A ++ L + LG Sbjct: 57 LVFVGETGSGKTT--QIPQYVLYDELPHQTGKLIACTQPRRVAAMSVAQRVADELDVKLG 114 Query: 131 DYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEAD 190 + + T+ ++ + GQ + R ++LDEA Sbjct: 115 EEVGYSIR-FENKTSSKTLLKYMTDGQLLREAMHDR----------DMSRYSCIILDEAH 163 Query: 191 -EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLE 249 L + +++++SATL + + + F P+ + R Sbjct: 164 ERTLATDILMALLKQLSERRKDLKIIVMSATL--DAQKFQSYFFNAPLLAVPGR----TH 217 Query: 250 GIKQFFVAVEREEWKFDTLCDLYDTL---TITQAVIFCNTKRKVDWLTEKMR-------- 298 ++ F+ ++ + + ++F + +++ ++ Sbjct: 218 PVEIFYTPEAERDYVEAAIRTVLQIHACEPEGDILLFLTGEEEIEDACRRISLEVDEMIR 277 Query: 299 ---EANFTVSSMHGDMPQKERESIMKE----FRSGAS---RVLISTDVWARGLDVPQVSL 348 +V ++G +P +++ I ++ FR G + +++T++ L + + Sbjct: 278 ESDAGPMSVYPLYGTLPPHQQQRIFEKAPQPFRPGGRPGRKCIVATNIAETSLTIDGIVY 337 Query: 349 II--------NYDLPNNRELYI----------HRIGRSGRYGRKGVAINFVKND 384 ++ Y+ E + R GR+GR R G + Sbjct: 338 VVDPGFSKQKIYNPRTRVESLLVSPISKASAQQRAGRAGR-TRPGKCFRLYTEE 390 >3B6E-A nrPDB Length = 216 Score = 62.3 bits (150), Expect = 4e-10, Method: Composition-based stats. Identities = 17/139 (12%), Positives = 46/139 (33%), Gaps = 9/139 (6%) Query: 62 SAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRE---TQALILAPTREL 118 Q + ++G+++I +G+GKT LD + + + ++L L Sbjct: 35 RPYQMEVAQPALEGKNIIICLPTGSGKTRVAVYIAKDHLDKKKKASEPGKVIVLVNKVLL 94 Query: 119 AVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV------FDMIR 172 Q+ + + G T + ++ ++ T + + Sbjct: 95 VEQLFRKEFQPFLKKWYRVIGLSGDTQLKISFPEVVKSCDIIISTAQILENSLLNLENGE 154 Query: 173 RRSLRTRAIKMLVLDEADE 191 ++ ++++DE Sbjct: 155 DAGVQLSDFSLIIIDECHH 173 >6FA9-A nrPDB Length = 655 Score = 61.9 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 57/368 (15%), Positives = 128/368 (34%), Gaps = 51/368 (13%) Query: 69 IKQIIKGRDVIAQSQSGTGKTATFSIS-VLQCLDIQVRETQALILAPTRELAVQIQKGLL 127 + + + + +I ++G+GKT I L + P R A+ + + Sbjct: 41 LDAVKEYQVLILVGETGSGKTT--QIPQYLHEAGYTKGNRKIACTQPRRVAAMSVAARV- 97 Query: 128 ALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLD 187 D M V+ +G + ED + T G + + S +++D Sbjct: 98 --ADEMGVRLGHEVGYSIRFEDCTSEKTILKYM--TDGMLLREMVT-SPDLADYSCIMID 152 Query: 188 EAD-EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDEL 246 EA ++ + P ++++ SATL E + + F PI + R Sbjct: 153 EAHERTVHTDILLALIKDLTRARPELRLIISSATLNAE--KFSAYFDDAPIFNVPGR--- 207 Query: 247 TLEGIKQFFVAVEREEWKFDTLCDLYDTL---TITQAVIFC-------NTKRKVDWLTEK 296 + ++ ++ + + L ++ ++F +V+ + K Sbjct: 208 -VHPVEVYYTSAPESNYLEAALVTVFQIHATQPEGDILVFLTGQEEIERACERVEEIRRK 266 Query: 297 M--REANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYD- 353 + R ++ +MP + + I + GA +V+ ST++ L + + +I+ Sbjct: 267 LGKRVPEIIALPIYSNMPSEMQAKIFEPTPPGARKVVFSTNIAETSLTIDGIVYVIDSGY 326 Query: 354 -------------------LPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIRILRDIEQ 394 +P +R R+GR+GR + G L ++++ Sbjct: 327 VKENTFSPVGTTGQSTLAVVPCSRAAANQRMGRAGRV-KPGKCFRLYTK--YAYLSEMDE 383 Query: 395 YYSTQIDE 402 + +I Sbjct: 384 SPTPEIQR 391 >4A2W-A nrPDB Length = 936 Score = 61.9 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 72/195 (36%), Gaps = 33/195 (16%) Query: 226 LEMTNKF-MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDT----LTITQA 280 +T KF +P I + +DE E K + L + D T+ Sbjct: 588 QHLTAKFQEKEPELIALSKDE-------------TNENPKLEELVCILDDAYRYNPQTRT 634 Query: 281 VIFCNTKRKVDWLTEKMREANF------TVSSMHGDMPQK------ERESIMKEFRSGA- 327 ++F T+ V L + M E V G Q ++ ++ F++ Sbjct: 635 LLFAKTRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKD 694 Query: 328 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIR 387 +R+LI+T V G+D+ Q +L++ Y+ N I GR GR I ++ Sbjct: 695 NRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGR-GRAA-GSKCILVTSKTEVV 752 Query: 388 ILRDIEQYYSTQIDE 402 +Y +++ Sbjct: 753 ENEKCNRYKEEMMNK 767 Score = 60.3 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 43/275 (15%), Positives = 92/275 (33%), Gaps = 30/275 (10%) Query: 12 SARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAI------- 64 +A+ + D ++ E S D L E+L G A G KP + Sbjct: 194 NAKDVDSEMTDASEDCLEASMTYSEEAEPDD-NLSENL--GSAAEGIGKPPPVYETKKAR 250 Query: 65 --QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD--IQVRETQALILAPTRELAV 120 Q + I G++ + + +G+GKT + R+ + + LA + Sbjct: 251 SYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKAKVVFLATKVPVYE 310 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSL-RTR 179 Q + + G + K+ ++ TP + + +L Sbjct: 311 QQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFEDGTLTSLS 370 Query: 180 AIKMLVLDEAD--------EMLNKGFKEQIYDVYRYLPPATQVVLISATL----PHEILE 227 +++ DE +L + EQ ++ LP Q++ ++A++ I E Sbjct: 371 IFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNSASQLP---QILGLTASVGVGNAKNIEE 427 Query: 228 MTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREE 262 + + ++ E I++ + + E Sbjct: 428 TIEHICSLCSYLDIQAISTVRENIQELQRFMNKPE 462 >4A2Q-A nrPDB Length = 797 Score = 61.1 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 72/195 (36%), Gaps = 33/195 (16%) Query: 226 LEMTNKF-MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDT----LTITQA 280 +T KF +P I + +DE E K + L + D T+ Sbjct: 588 QHLTAKFQEKEPELIALSKDE-------------TNENPKLEELVCILDDAYRYNPQTRT 634 Query: 281 VIFCNTKRKVDWLTEKMREANF------TVSSMHGDMPQK------ERESIMKEFRSGA- 327 ++F T+ V L + M E V G Q ++ ++ F++ Sbjct: 635 LLFAKTRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKD 694 Query: 328 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIR 387 +R+LI+T V G+D+ Q +L++ Y+ N I GR GR I ++ Sbjct: 695 NRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGR-GRAA-GSKCILVTSKTEVV 752 Query: 388 ILRDIEQYYSTQIDE 402 +Y +++ Sbjct: 753 ENEKCNRYKEEMMNK 767 Score = 60.0 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 43/275 (15%), Positives = 92/275 (33%), Gaps = 30/275 (10%) Query: 12 SARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAI------- 64 +A+ + D ++ E S D L E+L G A G KP + Sbjct: 194 NAKDVDSEMTDASEDCLEASMTYSEEAEPDD-NLSENL--GSAAEGIGKPPPVYETKKAR 250 Query: 65 --QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD--IQVRETQALILAPTRELAV 120 Q + I G++ + + +G+GKT + R+ + + LA + Sbjct: 251 SYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKAKVVFLATKVPVYE 310 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSL-RTR 179 Q + + G + K+ ++ TP + + +L Sbjct: 311 QQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFEDGTLTSLS 370 Query: 180 AIKMLVLDEAD--------EMLNKGFKEQIYDVYRYLPPATQVVLISATL----PHEILE 227 +++ DE +L + EQ ++ LP Q++ ++A++ I E Sbjct: 371 IFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNSASQLP---QILGLTASVGVGNAKNIEE 427 Query: 228 MTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREE 262 + + ++ E I++ + + E Sbjct: 428 TIEHICSLCSYLDIQAISTVRENIQELQRFMNKPE 462 >4A36-A nrPDB Length = 556 Score = 60.3 bits (145), Expect = 1e-09, Method: Composition-based stats. Identities = 40/195 (20%), Positives = 72/195 (36%), Gaps = 33/195 (16%) Query: 226 LEMTNKF-MTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDT----LTITQA 280 +T KF +P I + +DE E K + L + D T+ Sbjct: 347 QHLTAKFQEKEPELIALSKDE-------------TNENPKLEELVCILDDAYRYNPQTRT 393 Query: 281 VIFCNTKRKVDWLTEKMREANF------TVSSMHGDMPQK------ERESIMKEFRSGA- 327 ++F T+ V L + M E V G Q ++ ++ F++ Sbjct: 394 LLFAKTRALVSALKKCMEENPILNYIKPGVLMGRGRRDQTTGMTLPSQKGVLDAFKTSKD 453 Query: 328 SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDIR 387 +R+LI+T V G+D+ Q +L++ Y+ N I GR GR I ++ Sbjct: 454 NRLLIATSVADEGIDIVQCNLVVLYEYSGNVTKMIQVRGR-GRAA-GSKCILVTSKTEVV 511 Query: 388 ILRDIEQYYSTQIDE 402 +Y +++ Sbjct: 512 ENEKCNRYKEEMMNK 526 Score = 56.9 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 32/223 (14%), Positives = 76/223 (34%), Gaps = 18/223 (8%) Query: 55 AYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLD--IQVRETQALIL 112 A +K + Q + I G++ + + +G+GKT + R+ + + L Sbjct: 2 AMETKKARSYQIELAQPAINGKNALICAPTGSGKTFVSILICEHHFQNMPAGRKAKVVFL 61 Query: 113 APTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIR 172 A + Q + + G + K+ ++ TP + + Sbjct: 62 ATKVPVYEQQKNVFKHHFERQGYSVQGISGENFSNVSVEKVIEDSDIIVVTPQILVNSFE 121 Query: 173 RRSL-RTRAIKMLVLDEAD--------EMLNKGFKEQIYDVYRYLPPATQVVLISATL-- 221 +L +++ DE +L + EQ ++ LP Q++ ++A++ Sbjct: 122 DGTLTSLSIFTLMIFDECHNTTGNHPYNVLMTRYLEQKFNSASQLP---QILGLTASVGV 178 Query: 222 --PHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREE 262 I E + + ++ E I++ + + E Sbjct: 179 GNAKNIEETIEHICSLCSYLDIQAISTVRENIQELQRFMNKPE 221 >6I3O-A nrPDB Length = 677 Score = 59.2 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 64/350 (18%), Positives = 131/350 (37%), Gaps = 50/350 (14%) Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILA--PTRELAVQIQK 124 + I+ + + +I ++G+GKT V Q L +I P R AV + K Sbjct: 20 QIIQAVKDNQILIVVGETGSGKT----TQVTQYLAEAGFTKYGMIGCTQPRRVAAVSVAK 75 Query: 125 GLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSL---RTRAI 181 + + + Q +G T ED+ + T G M++R L + Sbjct: 76 RV---AEEVGCQLGQEVGYTIRFEDVTS--PATKIKYMTDG----MLQREILMDPDLKRY 126 Query: 182 KMLVLDEAD-EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL 240 +++LDEA + + P +V++ SATL + + + F + PI + Sbjct: 127 SVIMLDEAHERTIATDVLFALLKKTVKRRPDLKVIVTSATL--DAEKFSEYFNSCPIFTI 184 Query: 241 VKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRK----VDWLTEK 296 R +E + + E T+ ++ T ++F + + + L E+ Sbjct: 185 PGR-TFPVEILYSREPEPDYLEAALTTVMQIHLTEPPGDILVFLTGQEEIDTACEILYER 243 Query: 297 MREANFTVSS-----MHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLIIN 351 M+ +V ++ +P + + I + G+ +V+I+T++ + + + +++ Sbjct: 244 MKALGPSVPELIILPIYSALPSEMQSRIFEPAPPGSRKVVIATNIAETSITIDYIYYVVD 303 Query: 352 --------YDL----------PNNRELYIHRIGRSGRYGRKGVAINFVKN 383 YD P ++ R GR+GR G G Sbjct: 304 PGFVKQNAYDPKLGMDSLVVTPISQAQANQRAGRAGRTG-PGKCFRLYTE 352 >6BOG-A nrPDB Length = 968 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 25/115 (21%), Positives = 49/115 (42%), Gaps = 3/115 (2%) Query: 262 EWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMRE-ANFTVSSMHGDMPQKERESIM 320 + + + L + + ++ C L + +RE + H M ER+ Sbjct: 488 DPRVEWLMGYLTSHRSQKVLVICAKAATALQLEQVLREREGIRAAVFHEGMSIIERDRAA 547 Query: 321 KEFRSGA--SRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGR 373 F ++VL+ +++ + G + S ++ +DLP N +L RIGR R G+ Sbjct: 548 AWFAEEDTGAQVLLCSEIGSEGRNFQFASHMVMFDLPFNPDLLEQRIGRLDRIGQ 602 Score = 34.2 bits (77), Expect = 0.099, Method: Composition-based stats. Identities = 32/177 (18%), Positives = 67/177 (37%), Gaps = 30/177 (16%) Query: 78 VIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQC 137 V+ + G GKT + +L + + LI+ P +Q + L+ + N++ Sbjct: 173 VLLADEVGLGKTIEAGM-ILHQQLLSGAAERVLIIVPE---TLQ-HQWLVEMLRRFNLRF 227 Query: 138 HACIGGTNVGEDIRKLD--YGQHVVAGTPGRVFDMIRRRSLRTRAI-----KMLVLDEAD 190 + + +V + D RR R + +LV+DEA Sbjct: 228 ALFDDERYAEAQHDAYNPFDTEQLVICS----LDFARRSKQRLEHLCEAEWDLLVVDEAH 283 Query: 191 EML------NKGFKEQIYDVYRYLPPATQVVLISATLPHEI---LEMTNKFMTDPIR 238 ++ ++ ++ I + ++P V+L++AT P ++ + DP R Sbjct: 284 HLVWSEDAPSREYQA-IEQLAEHVPG---VLLLTAT-PEQLGMESHFARLRLLDPNR 335 >5N8S-A nrPDB Length = 944 Score = 56.1 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 60/430 (13%), Positives = 135/430 (31%), Gaps = 92/430 (21%) Query: 67 RAIKQIIKGRDVIAQSQSGTGKTA-TFSISVLQCLDIQVRET-QALILAPTRELAVQIQK 124 I+ + + + ++ +G GKT I + + + + + P R A+ I + Sbjct: 161 DIIQAVRENQVILIVGSTGCGKTTQVPQILLDDAISRGCASSCRIICTQPRRISAIAIAE 220 Query: 125 GLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKML 184 + Y + G + + RK + T G + ++ L + +L Sbjct: 221 WV----SYERCESLGNSVGYQIRLESRKARERASITYCTTGVLLQQLQSDPL-MHNLSVL 275 Query: 185 VLDEADEM-----LNKG-------FKEQIYDVYRYL----------PPATQVVLISATLP 222 +LDE E L G + + + + I + Sbjct: 276 ILDEIHERSVETDLLMGLLKVILPHRPDLKVILMSATVREQDFCDYFNNCPMFRIEGVMF 335 Query: 223 HEILEMTNKFM----------------TDPIRILVKRDELTLE---GIKQFF-------- 255 + + DP +K + + I+ + Sbjct: 336 PVKMLYLEDVLSKTNYEFQKFRDRRPKRDPPERRMKHEAMIEPYLRRIRNSYDSRVLDKL 395 Query: 256 -----VAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREA---------- 300 E ++ D + + + ++F K+ L + + Sbjct: 396 RLPESEGCEDIDFIADLVYYICENEPEGAILVFLPGYDKISQLYNILDKPKTSKGQRWRD 455 Query: 301 NFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLII--------NY 352 + V +H M E++++ + +G +V+IST + + + V +I NY Sbjct: 456 HMAVFPLHSLMQSGEQQAVFRRPPAGQRKVIISTIIAETSVTIDDVVYVINSGRTKATNY 515 Query: 353 DLPNNRELY----------IHRIGRSGRYGRKGVAINFVKNDDIRILRDI--EQYYSTQI 400 D+ N + R GR+GR R G+ N + DI + +++ Sbjct: 516 DIETNIQSLDEVWVTKANTQQRRGRAGRV-RPGICYNLFSRAREDRMDDIPTPEILRSKL 574 Query: 401 DEMPMNVADL 410 + + +++ L Sbjct: 575 ESIILSLKLL 584 >3RC8-A nrPDB Length = 677 Score = 55.3 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 63/150 (42%), Gaps = 22/150 (14%) Query: 265 FDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFR 324 D + D L ++ C +K + ++ ++ + ++G +P + + K+F Sbjct: 309 LDHALESLDNLRPGDCIV-CFSKNDIYSVSRQIEIRGLESAVIYGSLPPGTKLAQAKKFN 367 Query: 325 --SGASRVLISTDVWARGLDVPQVSLIINYDL--------------PNNRELYIHRIGRS 368 + ++L++TD GL++ + II Y L P + GR+ Sbjct: 368 DPNDPCKILVATDAIGMGLNLS-IRRIIFYSLIKPSINEKGERELEPITTSQALQIAGRA 426 Query: 369 GRYG---RKGVAINFVKNDDIRILRDIEQY 395 GR+ ++G ++D+ +L++I + Sbjct: 427 GRFSSRFKEGEVTTM-NHEDLSLLKEILKR 455 >4B6E-A nrPDB Length = 683 Score = 55.0 bits (131), Expect = 6e-08, Method: Composition-based stats. Identities = 46/268 (17%), Positives = 91/268 (33%), Gaps = 63/268 (23%) Query: 82 SQSGTGKT----ATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQC 137 + +G+GK+ A ++ + + L+L P+ L G YM+ + Sbjct: 239 APTGSGKSTKVPAAYA----------AQGYKVLVLNPSV-------AATLGFGAYMS-KA 280 Query: 138 HACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE-----M 192 H N+ +R + G V T G+ + A +++ DE + Sbjct: 281 HGI--DPNIRTGVRTITTGAPVTYSTYGK---FLADGGCSGGAYDIIICDECHSTDSTTI 335 Query: 193 LNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIK 252 L G + A VVL +AT P + I+ Sbjct: 336 LGIGTVLDQAETAG----ARLVVLATATPP-------------------GSVTVPHPNIE 372 Query: 253 QFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMP 312 + ++ E + + + + + +IFC++K+K D L K+ + + + Sbjct: 373 EVALSNTGEIPFYGKAIPI-EAIRGGRHLIFCHSKKKCDELAAKLSGLGINAVAYYRGLD 431 Query: 313 QKERESIMKEFRSGASRVLISTDVWARG 340 +I G V+++TD G Sbjct: 432 VSVIPTI------GDV-VVVATDALMTG 452 >4OK6-A nrPDB Length = 464 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 45/268 (16%), Positives = 91/268 (33%), Gaps = 63/268 (23%) Query: 82 SQSGTGKT----ATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQC 137 + +G+GK+ A ++ + + L+L P+ L G YM+ + Sbjct: 38 APTGSGKSTKVPAAYA----------AQGYKVLVLNPSV-------AATLGFGAYMS-KA 79 Query: 138 HACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE-----M 192 H N+ +R + G + T G+ + A +++ DE + Sbjct: 80 HGV--DPNIRTGVRTITTGSPITYSTYGK---FLADGGCSGGAYDIIICDECHSTDATSI 134 Query: 193 LNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIK 252 L G + A VVL +AT P ++ I+ Sbjct: 135 LGIGTVLDQAETAG----ARLVVLATATPP-------------------GSVTVSHPNIE 171 Query: 253 QFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMP 312 + ++ E + L + + + +IFC++K+K D L K+ + + + Sbjct: 172 EVALSTTGEIPFYGKAIPL-EVIKGGRHLIFCHSKKKCDELAAKLVALGINAVAYYRGLD 230 Query: 313 QKERESIMKEFRSGASRVLISTDVWARG 340 + + V++STD G Sbjct: 231 -------VSVIPTNGDVVVVSTDALMTG 251 >2ZJO-A nrPDB Length = 482 Score = 54.2 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 47/268 (17%), Positives = 94/268 (35%), Gaps = 63/268 (23%) Query: 82 SQSGTGKT----ATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQC 137 + +G+GK+ A ++ + + L+L P+ L G YM+ + Sbjct: 49 APTGSGKSTKVPAAYA----------AQGYKVLVLNPSV-------AATLGFGAYMS-KA 90 Query: 138 HACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE-----M 192 H N+ +R + G + T G+ + A +++ DE + Sbjct: 91 HGV--DPNIRTGVRTITTGAPITYSTYGK---FLADGGCSGGAYDIIMCDECHSTDSTTI 145 Query: 193 LNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIK 252 L G + A VVL +AT P + I+ Sbjct: 146 LGIGTVLDQAETAG----ARLVVLATATPP-------------------GSVTVPHPNIE 182 Query: 253 QFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMP 312 + ++ E + + +T+ + +IFC++K+K D L K+ + + + Sbjct: 183 EIALSNTGEIPFYGKAIPI-ETIKGGRHLIFCHSKKKCDELAAKLSALGIHAVAYYRGLD 241 Query: 313 QKERESIMKEFRSGASRVLISTDVWARG 340 S++ SG V+++TD G Sbjct: 242 ----VSVIPA--SGNV-VVVATDALMTG 262 >3MWY-W nrPDB Length = 800 Score = 53.8 bits (128), Expect = 1e-07, Method: Composition-based stats. Identities = 26/163 (15%), Positives = 57/163 (34%), Gaps = 13/163 (7%) Query: 221 LPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQA 280 + + KF ++T E + + + + D L + Sbjct: 526 FDNAEERVLQKF---------GDGKMTRENVLRGLIMSSGKMVLLDQLLTRLKK-DGHRV 575 Query: 281 VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRS---GASRVLISTDVW 337 +IF R +D L + + + G +P +R + F S L+ST Sbjct: 576 LIFSQMVRMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAG 635 Query: 338 ARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 380 G+++ ++ +D N + + + R+ R G+K + + Sbjct: 636 GLGINLMTADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVY 678 >6FTX-W nrPDB Length = 878 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 45/276 (16%), Positives = 87/276 (31%), Gaps = 31/276 (11%) Query: 133 MNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVF-DMIRRRSLR--TRAIKMLVLDEA 189 V I GT + +I++L + + PGR D + + R I+ +L Sbjct: 350 FKVANRMLITGTPLQNNIKELAALVNFLM--PGRFNQDEEQEEYIHDLHRRIQPFILRRL 407 Query: 190 DEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLE 249 + + K + + R Q L +T L+ + Sbjct: 408 KKDVEKSLPSKTERILRVELSDVQTEYYKNILTKNYSALTAGA-KGGHFSLLNIMNELKK 466 Query: 250 GIKQFFVAVEREEW--------------------KFDTLCDLYDTLTIT--QAVIFCNTK 287 ++ EE K L L L + +IF Sbjct: 467 ASNHPYLFDNAEERVLQKFMTRENVLRGLIMSSGKMVLLDQLLTRLKKDGHRVLIFSQMV 526 Query: 288 RKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRS---GASRVLISTDVWARGLDVP 344 R +D L + + + G +P +R + F S L+ST G+++ Sbjct: 527 RMLDILGDYLSIKGINFQRLDGTVPSAQRRISIDHFNSPDSNDFVFLLSTRAGGLGINLM 586 Query: 345 QVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAINF 380 ++ +D N + + + R+ R G+K + + Sbjct: 587 TADTVVIFDSDWNPQADLQAMARAHRIGQKNHVMVY 622 >6ID1-V nrPDB Length = 795 Score = 53.4 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 50/353 (14%), Positives = 118/353 (33%), Gaps = 52/353 (14%) Query: 71 QIIKGRDVIAQSQSGTGKTATFSISVLQCL-DIQVRETQALILAPTRELAVQIQKGLLAL 129 +++ + + ++G+GKT ++ + + + P R A+ + Sbjct: 149 ILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAM---SVAQRV 205 Query: 130 GDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEA 189 D M+V +G + ED + T G + L +++LDEA Sbjct: 206 ADEMDVMLGQEVGYSIRFEDCSSAKTILKYM--TDGMLLREAMNDPL-LERYGVIILDEA 262 Query: 190 D-EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTL 248 L + +V+++SATL KF + Sbjct: 263 HERTLATDILMGVLKEVVRQRSDLKVIVMSATLD------AGKFQIYFDNCPLLTIPGRT 316 Query: 249 EGIKQFFVAVEREEWKFDTLCDLYDTL----TITQAVIFCNTKRKVDWLTEKMREA---- 300 ++ F+ ++ + + ++F + ++D ++++ Sbjct: 317 HPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDL 376 Query: 301 -----NFTVSSMHGDMPQKERESIMK----EFRSGAS--RVLISTDVWARGLDVPQVSLI 349 + + ++ +P ++++ I + + ++GA +V++ST++ L + V + Sbjct: 377 GPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFV 436 Query: 350 I--------NYDLPNNRELYI----------HRIGRSGRYGRKGVAINFVKND 384 I Y+ E + R GR+GR R G Sbjct: 437 IDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR-TRPGKCFRLYTEK 488 >3H1T-A nrPDB Length = 590 Score = 52.6 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 68/421 (16%), Positives = 126/421 (29%), Gaps = 86/421 (20%) Query: 24 TKVEFETSEEVDVTPTFDTM----GLRED----LLRGIYAYGFEKPSAIQQRAIK----Q 71 T E S F + G++++ LL + P QQ AI Sbjct: 134 TGEEQLLSRFPTPDELFKRLCGDEGIKDEDLDTLLSPYHHVSGYSPRYYQQIAINRAVQS 193 Query: 72 IIKG--RDVIAQSQSGTGKTA-TFSIS-----VLQCLDIQVRETQALILAPTRELAVQIQ 123 +++G R +I + +GTGKT F IS R+ + L LA L + Sbjct: 194 VLQGKKRSLITMA-TGTGKTVVAFQISWKLWSARWNRTGDYRKPRILFLADRNVL---VD 249 Query: 124 KGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVV--AGTPGRVFDMIRRRSLRTRAI 181 H GG V Q + PG + + Sbjct: 250 DPKDKTFTPFGDARHKIEGGKVVKSREIYFAIYQSIASDERRPGLYKEFPQ------DFF 303 Query: 182 KMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRIL- 240 ++++DE + ++ Y PA Q+ + +AT E T ++ +PI Sbjct: 304 DLIIIDECHRGSARD-NSNWREILEYFEPAFQIGM-TATPLREDNRDTYRYFGNPIYTYS 361 Query: 241 ----------------------------------------VKRDELTLEGIKQFFVAVER 260 + E + ++ R Sbjct: 362 LRQGIDDGFLAPYRVHRVISEVDAAGWRPSKGDVDRFGREIPDGEYQTKDFERVIALKAR 421 Query: 261 EEWKFDTLCDLYDTL-TITQAVIFCNTKRKVDWLTEKMREANFTVSSMH----GDMPQKE 315 + L D + ++FC + D + + N +S H + +E Sbjct: 422 TDAFAKHLTDFMKRTDRFAKTIVFCVDQEHADEMRRALNNLNSDLSRKHPDYVARVTSEE 481 Query: 316 ------RESIMKEFRSGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSG 369 S +E + +L ++ + G+D P ++ + N+ + +GR Sbjct: 482 GKIGKGHLSRFQELETSTPVILTTSQLLTTGVDAPTCKNVVLARVVNSMSEFKQIVGRGT 541 Query: 370 R 370 R Sbjct: 542 R 542 >5XDR-A nrPDB Length = 690 Score = 52.6 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 50/353 (14%), Positives = 118/353 (33%), Gaps = 52/353 (14%) Query: 71 QIIKGRDVIAQSQSGTGKTATFSISVLQCL-DIQVRETQALILAPTRELAVQIQKGLLAL 129 +++ + + ++G+GKT ++ + + + P R A+ + Sbjct: 44 ILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPRRVAAM---SVAQRV 100 Query: 130 GDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEA 189 D M+V +G + ED + T G + L +++LDEA Sbjct: 101 ADEMDVMLGQEVGYSIRFEDCSSAKTILKYM--TDGMLLREAMNDPL-LERYGVIILDEA 157 Query: 190 D-EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTL 248 L + +V+++SATL KF + Sbjct: 158 HERTLATDILMGVLKEVVRQRSDLKVIVMSATLD------AGKFQIYFDNCPLLTIPGRT 211 Query: 249 EGIKQFFVAVEREEWKFDTLCDLYDTL----TITQAVIFCNTKRKVDWLTEKMREA---- 300 ++ F+ ++ + + ++F + ++D ++++ Sbjct: 212 HPVEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDL 271 Query: 301 -----NFTVSSMHGDMPQKERESIMK----EFRSGAS--RVLISTDVWARGLDVPQVSLI 349 + + ++ +P ++++ I + + ++GA +V++ST++ L + V + Sbjct: 272 GPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFV 331 Query: 350 I--------NYDLPNNRELYI----------HRIGRSGRYGRKGVAINFVKND 384 I Y+ E + R GR+GR R G Sbjct: 332 IDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR-TRPGKCFRLYTEK 383 >3DIN-A nrPDB Length = 871 Score = 52.6 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 31/159 (19%), Positives = 69/159 (43%), Gaps = 17/159 (10%) Query: 259 EREEWKFDTLCDLYDT--LTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKER 316 ++ K++ + + + ++ + K + L+ +++ ++ +KE Sbjct: 454 RTQKEKYEKIVEEIEKRYKKGQPVLVGTTSIEKSELLSSMLKKKGIPHQVLNAKYHEKEA 513 Query: 317 ESIMKEFRSGASRVLISTDVWARGLDV---PQVS-----LIINYDLPNNRELYIHRIGRS 368 E + K + G V I+T++ RG D+ P V+ II + +R + GR+ Sbjct: 514 EIVAKAGQKGM--VTIATNMAGRGTDIKLGPGVAELGGLCIIGTERHESRRIDNQLRGRA 571 Query: 369 GRYGRKGVAINFVKNDDIRILRDIEQYYSTQIDEMPMNV 407 GR G G +I F+ +D D+ + + ++ MN+ Sbjct: 572 GRQGDPGESIFFLSLED-----DLLRIFGSEQIGKVMNI 605 Score = 33.4 bits (75), Expect = 0.20, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 32/89 (35%), Gaps = 8/89 (8%) Query: 11 GSARKRLLKEE---DMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQR 67 R + E M E S E F+ L + R +P +Q Sbjct: 26 SDLRSKKNSELIRLSMVLKEKVNSFEDADEHLFEAFALVREAARRTLGM---RPFDVQVM 82 Query: 68 AIKQIIKGRDVIAQSQSGTGKTATFSISV 96 + +G+ +A+ ++G GKT ++ + Sbjct: 83 GGIALHEGK--VAEMKTGEGKTLAATMPI 109 >5X0Y-O nrPDB Length = 735 Score = 51.5 bits (122), Expect = 7e-07, Method: Composition-based stats. Identities = 34/150 (22%), Positives = 63/150 (42%), Gaps = 17/150 (11%) Query: 264 KFDTLCDLYDTL--TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK 321 KF+ L + L T + +IF + +D + + +R N + G ER +++ Sbjct: 423 KFELLDRILPKLKATGHRVLIFFQMTQIMDIMEDFLRYINIKYLRLDGHTKSDERSELLR 482 Query: 322 EFRSGASRVLI---STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI 378 F + S L ST GL++ +I +D N + R+ R G+K Sbjct: 483 LFNAPDSEYLCFILSTRAGGLGLNLQTADTVIIFDTDWNPHQDLQAQDRAHRIGQK---- 538 Query: 379 NFVKNDDIRILRDIEQYYSTQIDEMPMNVA 408 +++RILR I + ++E+ + A Sbjct: 539 -----NEVRILRLI---TTNSVEEVILERA 560 >5WDX-A nrPDB Length = 649 Score = 51.1 bits (121), Expect = 9e-07, Method: Composition-based stats. Identities = 52/320 (16%), Positives = 103/320 (32%), Gaps = 77/320 (24%) Query: 26 VEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSG 85 + ET + V +PTF + + Y G+ + +G Sbjct: 188 IPVETLDVVTRSPTFSDNSTPPAVPQT-YQVGYLH---------------------APTG 225 Query: 86 TGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTN 145 +GK+ + + + + L+L P+ L G Y++ + H N Sbjct: 226 SGKST--KVP----VAYAAQGYKVLVLNPSV-------AATLGFGAYLS-KAHGI--NPN 269 Query: 146 VGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADE-----MLNKGFKEQ 200 + +R + G+ + T G+ + + A +++ DE +L G Sbjct: 270 IRTGVRTVMTGEAITYSTYGK---FLADGGCASGAYDIIICDECHAVDATSILGIGTVLD 326 Query: 201 IYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVER 260 + VL +AT P I++ + E Sbjct: 327 QAETAGV----RLTVLATATPP-------------------GSVTTPHPDIEEVGLGREG 363 Query: 261 EEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIM 320 E + L + + +IFC++K+K D L +R + + + SI+ Sbjct: 364 EIPFYGRAIPL-SCIKGGRHLIFCHSKKKCDELAAALRGMGLNAVAYYRGLD----VSII 418 Query: 321 KEFRSGASRVLISTDVWARG 340 G V+++TD G Sbjct: 419 PA--QGDV-VVVATDALMTG 435 >5JXR-A nrPDB Length = 723 Score = 49.2 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 47/115 (40%), Gaps = 5/115 (4%) Query: 264 KFDTLCDLYDTLT--ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK 321 K L L + ++ +IF R +D L + + + G ++R + + Sbjct: 411 KMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAID 470 Query: 322 EFR---SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGR 373 E+ S L++T G+++ ++I YD N + + + R+ R G+ Sbjct: 471 EYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQ 525 >5JXT-B nrPDB Length = 349 Score = 49.2 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 47/115 (40%), Gaps = 5/115 (4%) Query: 264 KFDTLCDLYDTLT--ITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK 321 K L L + ++ +IF R +D L + + + G ++R + + Sbjct: 86 KMVVLDKLLKRIQKQGSRVLIFSQMSRLLDILEDYCVFRGYKYCRIDGSTAHEDRIAAID 145 Query: 322 EFR---SGASRVLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGR 373 E+ S L++T G+++ ++I YD N + + + R+ R G+ Sbjct: 146 EYNKPGSDKFIFLLTTRAGGLGINLTTADIVILYDSDWNPQADLQAMDRAHRIGQ 200 >5HZR-A nrPDB Length = 732 Score = 48.4 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 32/150 (21%), Positives = 61/150 (40%), Gaps = 17/150 (11%) Query: 264 KFDTLCDLYDT--LTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK 321 KF+ L + T + ++F +D + + +R + G ++R +++ Sbjct: 430 KFELLDRILPKYKATGHRVLMFFQMTAIMDIMEDFLRFRGLHYLRLDGTTKSEDRSELLR 489 Query: 322 EFRSGASR---VLISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI 378 +F S L+ST GL++ +I YD N + R+ R G+K Sbjct: 490 QFNQPDSPYFMFLLSTRAGGLGLNLQTADTVIIYDSDWNPHQDLQAQDRAHRIGQK---- 545 Query: 379 NFVKNDDIRILRDIEQYYSTQIDEMPMNVA 408 +++RILR I S ++E + A Sbjct: 546 -----NEVRILRLIS---SASVEEKILERA 567 >5K8T-A nrPDB Length = 458 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 56/306 (18%), Positives = 101/306 (33%), Gaps = 60/306 (19%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALG-DYMNVQCHACIGG 143 G GKT + + + + +ILAPTR +A ++++ L L YM + G Sbjct: 34 GAGKTRR-VLPEIVR-EAIKTRLRTVILAPTRVVAAEMEEALRGLPVRYMTTAVNVTHSG 91 Query: 144 TNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYD 203 T + +D H + R+ IR + ++DEA F + Sbjct: 92 TEI------VDLMCHATFTS--RLLQPIRVPNYNL-----YIMDEAH------FTDP-SS 131 Query: 204 VYRYLPPATQVVLISATLPHEILEMTNKFMT--DPIRILVKRDELTLEGIKQFFVAVERE 261 + +T+V + A FMT P RD VE Sbjct: 132 IAARGYISTRVEMGEA---------AAIFMTATPPGT----RDAFPDSNSPIMDTEVEVP 178 Query: 262 EWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMK 321 E + + D + + V F + R + + + +A V + + E + Sbjct: 179 ERAWSSGFDWVTDHS-GKTVWFVPSVRNGNEIAACLTKAGKRVIQLSRKTFETE----FQ 233 Query: 322 EFRSGASRVLISTDVWARGLDVPQVSLI--------INYD---------LPNNRELYIHR 364 + + +++TD+ G + +I + D +P R Sbjct: 234 KTKHQEWDFVVTTDISEMGANFKADRVIDSRRCLKPVILDGERVILAGPMPVTHASAAQR 293 Query: 365 IGRSGR 370 GR GR Sbjct: 294 RGRIGR 299 >2WV9-A nrPDB Length = 673 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 50/309 (16%), Positives = 93/309 (30%), Gaps = 64/309 (20%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT +++ D + + +LAPTR +A ++ + L + Sbjct: 251 GAGKTRRILPQIIK--DAIQKRLRTAVLAPTRVVAAEMAEALR------GLPVRYLTPAV 302 Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204 ++ T R+ +R + V+DEA F + Sbjct: 303 QREHSGNEIVDVMCHATLTH-RLMSPLRVPNYNL-----FVMDEAH------FTD----- 345 Query: 205 YRYLPPATQVVLISATLPHEILEMTNKFMT--DPIRILVKRDELTLEGIKQFFVAVEREE 262 P + AT E E FMT P D + V E Sbjct: 346 ----PASIAARGYIATR-VEAGEAAAIFMTATPPGTSDPFPDTNS-------PVHDVSSE 393 Query: 263 WKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIM 320 ++ +T V F + + + + + ++ A V ++ E Sbjct: 394 IPDRAWSSGFEWITDYAGKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTE----Y 449 Query: 321 KEFRSGASRVLISTDVWARGLDVPQVSLI-----------------INYDLPN--NRELY 361 + ++G +I+TD+ G + +I + +P+ Sbjct: 450 PKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILSVPSAITSASA 509 Query: 362 IHRIGRSGR 370 R GR GR Sbjct: 510 AQRRGRVGR 518 >1YKS-A nrPDB Length = 440 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 57/317 (17%), Positives = 101/317 (31%), Gaps = 81/317 (25%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHA-CIGG 143 G GKT F +L + R + L+LAPTR + + ++V+ H Sbjct: 18 GAGKTRRFLPQILA--ECARRRLRTLVLAPTRV----VLSEMKEAFHGLDVKFHTQAFSA 71 Query: 144 TNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAI---KMLVLDEADEMLNKGFKEQ 200 G ++ +D H T + R L + +++++DEA F + Sbjct: 72 HGSGREV--IDAMCH---AT-------LTYRMLEPTRVVNWEVIIMDEAH------FLDP 113 Query: 201 IYDVY-------RYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEG--I 251 + R + +L++AT P DE I Sbjct: 114 -ASIAARGWAAHRARANESATILMTATPPGT------------------SDEFPHSNGEI 154 Query: 252 KQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDM 311 + + E W L D F + R + + +R+A +V + + Sbjct: 155 EDVQTDIPSEPWNTGHDWILADKRPTAW---FLPSIRAANVMAASLRKAGKSVVVL--NR 209 Query: 312 PQKERESIMKEFRSGASRVLISTDVWARGLD--VPQV----------------SLIINYD 353 ERE + +++TD+ G + V +V + I Sbjct: 210 KTFERE--YPTIKQKKPDFILATDIAEMGANLCVERVLDCRTAFKPVLVDEGRKVAIKGP 267 Query: 354 LPNNRELYIHRIGRSGR 370 L + R GR GR Sbjct: 268 LRISASSAAQRRGRIGR 284 >2V8O-A nrPDB Length = 444 Score = 44.9 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 50/309 (16%), Positives = 93/309 (30%), Gaps = 64/309 (20%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT +++ D + + +LAPTR +A ++ + L + Sbjct: 22 GAGKTRRILPQIIK--DAIQKRLRTAVLAPTRVVAAEMAEALR------GLPVRYLTPAV 73 Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204 ++ T R+ +R + V+DEA F + Sbjct: 74 QREHSGNEIVDVMCHATLTH-RLMSPLRVPNYNL-----FVMDEAH------FTD----- 116 Query: 205 YRYLPPATQVVLISATLPHEILEMTNKFMT--DPIRILVKRDELTLEGIKQFFVAVEREE 262 P + AT E E FMT P D + V E Sbjct: 117 ----PASIAARGYIATR-VEAGEAAAIFMTATPPGTSDPFPDTNS-------PVHDVSSE 164 Query: 263 WKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIM 320 ++ +T V F + + + + + ++ A V ++ E Sbjct: 165 IPDRAWSSGFEWITDYAGKTVWFVASVKMSNEIAQCLQRAGKRVIQLNRKSYDTE----Y 220 Query: 321 KEFRSGASRVLISTDVWARGLDVPQVSLI-----------------INYDLPN--NRELY 361 + ++G +I+TD+ G + +I + +P+ Sbjct: 221 PKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILDEGEGRVILSVPSAITSASA 280 Query: 362 IHRIGRSGR 370 R GR GR Sbjct: 281 AQRRGRVGR 289 >2BMF-A nrPDB Length = 451 Score = 44.9 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 49/318 (15%), Positives = 97/318 (30%), Gaps = 82/318 (25%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT + + + + R + LILAPTR +A ++++ L G Sbjct: 29 GAGKTKRY-LPAIVR-EAIKRGLRTLILAPTRVVAAEMEEALR---------------GL 71 Query: 145 NVGEDIRKLDYGQHVVAGTPGR-VFDMIRRRSLRTRAIK--------MLVLDEADEMLNK 195 + + +H GR + D++ + R + ++++DEA Sbjct: 72 PIRYQTPAIR-AEHT-----GREIVDLMCHATFTMRLLSPIRVPNYNLIIMDEAH----- 120 Query: 196 GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFF 255 + +T+V + A FMT + + Q Sbjct: 121 --FTDPASIAARGYISTRVEMGEA---------AGIFMT-------ATPPGSRDPFPQSN 162 Query: 256 VAVEREEWKFDTLCDLYDTL----TITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDM 311 + EE + + V F + + + + +R+ V + Sbjct: 163 APIMDEEREIPERSWNSGHEWVTDFKGKTVWFVPSIKAGNDIAACLRKNGKKVIQLSRKT 222 Query: 312 PQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSL---------IINYD--------- 353 E + R+ +++TD+ G + + +I D Sbjct: 223 FDSE----YIKTRTNDWDFVVTTDISEMGANFKAERVIDPRRCMKPVILTDGEERVILAG 278 Query: 354 -LPNNRELYIHRIGRSGR 370 +P R GR GR Sbjct: 279 PMPVTHSSAAQRRGRVGR 296 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 38/107 (35%), Gaps = 19/107 (17%) Query: 249 EGIKQFFV--AVEREEW--KFDTLCDLYDTLTITQAVI---FCNTKRKVDWLTEKMREAN 301 E + ++ +E +E + L D + + +I F + KVD + + R Sbjct: 301 ENDQYIYMGEPLENDEDCAHWKEAKMLLDNINTPEGIIPSMFEPEREKVDAIDGEYRLRG 360 Query: 302 FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSL 348 + R++ + R G V ++ V A G++ Sbjct: 361 ------------EARKTFVDLMRRGDLPVWLAYRVAAEGINYADRRW 395 >3BXZ-A nrPDB Length = 471 Score = 44.9 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 41/302 (13%), Positives = 100/302 (33%), Gaps = 40/302 (13%) Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 + + ++ IA+ ++G GKT T ++ + ++ LA + + Sbjct: 89 QLLGGMVLNERCIAEMRTGEGKTLTATLPA---YLNALTGKGVHVVTVNDYLAQRDAENN 145 Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV-FDMIRRRSL------RTR 179 L +++ + + G Y + GT FD +R R Sbjct: 146 RPLFEFLGLTVGINLPGMPAPAKREA--YAADITYGTNNEYGFDYLRDNMAFSPEERVQR 203 Query: 180 AIKMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVL----------------ISATLPH 223 + ++DE D +L + A Q + ++ T Sbjct: 204 KLHYALVDEVDSIL-----IDEARTPLIISGANQTLASITFQNYFRLYEKLAGMTGTADT 258 Query: 224 EILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTIT--QAV 281 E E ++ + D + + R + + ++ E K + + T + Sbjct: 259 EAFEFSSIYKLDTVVVPTNRPMIRKDLPDLVYM---TEAEKIQAIIEDIKERTAKGQPVL 315 Query: 282 IFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWARGL 341 + + K + ++ ++ +A + ++ E + + + V I+T++ RG Sbjct: 316 VGTISIEKSELVSNELTKAGIKHNVLNAKFHANEAAIVAQA--GYPAAVTIATNMAGRGT 373 Query: 342 DV 343 D+ Sbjct: 374 DI 375 >3LLM-A nrPDB Length = 235 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 35/178 (19%), Positives = 64/178 (35%), Gaps = 18/178 (10%) Query: 66 QRAIKQIIKGRDVIAQSQSGTGKTATFSIS--VLQCLDIQVRETQALILA--PTRELAVQ 121 ++ I + VI + +G GKT + +L R + I+ P R AV Sbjct: 67 SEILEAISQNSVVIIRGATGCGKTT--QVPQFILDDFIQNDRAAECNIVVTQPRRISAVS 124 Query: 122 IQKGL-LALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRA 180 + + + G+ C G +V + ++ T G + + R Sbjct: 125 VAERVAFERGEEPGKSC-----GYSVRFESILPRPHASIMFCTVGVLLRKLEAG---IRG 176 Query: 181 IKMLVLDEAD-EMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPI 237 I +++DE +N F + P ++VL+SAT+ + F PI Sbjct: 177 ISHVIVDEIHERDINTDFLLVVLRDVVQAYPEVRIVLMSATIDTSM--FCEYFFNCPI 232 >2Z83-A nrPDB Length = 459 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 50/309 (16%), Positives = 93/309 (30%), Gaps = 64/309 (20%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G+GKT +++ D + + +LAPTR +A ++ + L + Sbjct: 31 GSGKTRKILPQIIK--DAIQQRLRTAVLAPTRVVAAEMAEALR------GLPVRYQTSAV 82 Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDV 204 ++ T R+ R + V+DEA F + Sbjct: 83 QREHQGNEIVDVMCHATLTH-RLMSPNRVPNYNL-----FVMDEAH------FTD----- 125 Query: 205 YRYLPPATQVVLISATLPHEILEMTNKFM--TDPIRILVKRDELTLEGIKQFFVAVEREE 262 P + AT E+ E FM T P D + ++E Sbjct: 126 ----PASIAARGYIAT-KVELGEAAAIFMTATPPGTTDPFPDSNA-------PIHDLQDE 173 Query: 263 WKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIM 320 Y+ +T V F + + + + ++ A V ++ E Sbjct: 174 IPDRAWSSGYEWITEYAGKTVWFVASVKMGNEIAMCLQRAGKKVIQLNRKSYDTE----Y 229 Query: 321 KEFRSGASRVLISTDVWARGLDVPQVSLI-----------------INYDLPN--NRELY 361 + ++G +I+TD+ G + +I + P+ Sbjct: 230 PKCKNGDWDFVITTDISEMGANFGASRVIDCRKSVKPTILEEGEGRVILGNPSPITSASA 289 Query: 362 IHRIGRSGR 370 R GR GR Sbjct: 290 AQRRGRVGR 298 >2JLW-A nrPDB Length = 451 Score = 43.4 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 52/314 (16%), Positives = 96/314 (30%), Gaps = 74/314 (23%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT + + + R + LILAPTR +A ++++ L + Sbjct: 29 GAGKTKR-ILPSIVR-EALKRRLRTLILAPTRVVAAEMEEALR------GLPIRYQTPAV 80 Query: 145 NVGEDIRKL-DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYD 203 R++ D H T R+ R + +V+DEA F + Sbjct: 81 KSDHTGREIVDLMCHATFTT--RLLSSTRVPNYNL-----IVMDEAH------FTDPCSV 127 Query: 204 VYRYLPPATQVVL------ISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257 R + ++AT P I +E I+ Sbjct: 128 AARGYISTRVEMGEAAAIFMTATPPGSIDPFPQS-------------NSPIEDIE----- 169 Query: 258 VEREEWKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKE 315 E + +D +T Q V F + + + + +R++ V + E Sbjct: 170 ---REIPERSWNTGFDWITDYQGKTVWFVPSIKAGNDIANCLRKSGKRVIQLSRKTFDTE 226 Query: 316 RESIMKEFRSGASRVLISTDVWARG--------LDVPQV-----------SLIINYDLPN 356 + + +++TD+ G +D + +I+ +P Sbjct: 227 ----YPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVILAGPIPV 282 Query: 357 NRELYIHRIGRSGR 370 R GR GR Sbjct: 283 TPASAAQRRGRIGR 296 >1Z6A-A nrPDB Length = 500 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 47/106 (44%), Gaps = 3/106 (2%) Query: 276 TITQAVIFCNTKRKVDWLTEKM-REANFTVSSMHGDMPQKERESIMKEFRSGASR--VLI 332 + IF + + +E N V ++G++ +KER+ I+ +F++ S +++ Sbjct: 340 EGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKERDDIISKFQNNPSVKFIVL 399 Query: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI 378 S G+++ + +I++D N + R R G+ I Sbjct: 400 SVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQTRNVI 445 >1TF2-A nrPDB Length = 844 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 54/140 (38%), Gaps = 14/140 (10%) Query: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 P +Q + + IA+ ++G GKT T ++ V + ++ LA Sbjct: 84 PFKVQLMG-GVALHDGN-IAEMKTGEGKTLTSTLPV---YLNALTGKGVHVVTVNEYLAS 138 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPG-------RVFDMIRR 173 + + + + +++ + + + +D ++ Y + T R ++ + Sbjct: 139 RDAEQMGKIFEFLGLTVGLNLNSMS--KDEKREAYAADITYSTNNELGFDYLRDNMVLYK 196 Query: 174 RSLRTRAIKMLVLDEADEML 193 + R + V+DE D +L Sbjct: 197 EQMVQRPLHFAVIDEVDSIL 216 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 21/133 (15%), Positives = 55/133 (41%), Gaps = 15/133 (11%) Query: 275 LTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST 334 +T ++ + +++ ++ ++ ++E + I + + GA V I+T Sbjct: 430 MTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGA--VTIAT 487 Query: 335 DVWARGLDVP---QVS-----LIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDI 386 ++ RG D+ V ++ + +R + GRSGR G G+ ++ +D Sbjct: 488 NMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMED- 546 Query: 387 RILRDIEQYYSTQ 399 ++ + + + Sbjct: 547 ----ELMRRFGAE 555 >2WZQ-A nrPDB Length = 619 Score = 43.0 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 51/314 (16%), Positives = 95/314 (30%), Gaps = 74/314 (23%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT + + + R + LILAPTR +A ++++ L + Sbjct: 197 GAGKTKR-ILPSIVR-EALKRRLRTLILAPTRVVAAEMEEALR------GLPIRYQTPAV 248 Query: 145 NVGEDIRKL-DYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYD 203 R++ D H T R+ R + +V+DEA F + Sbjct: 249 KSDHTGREIVDLMCHATFTT--RLLSSTRVPNYNL-----IVMDEAH------FTDPCSV 295 Query: 204 VYRYLPPATQVVL------ISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVA 257 R + ++AT P +E I+ Sbjct: 296 AARGYISTRVEMGEAAAIFMTATPPGSTDPFPQS-------------NSPIEDIE----- 337 Query: 258 VEREEWKFDTLCDLYDTLTITQA--VIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKE 315 E + +D +T Q V F + + + + +R++ V + E Sbjct: 338 ---REIPERSWNTGFDWITDYQGKTVWFVPSIKAGNDIANCLRKSGKRVIQLSRKTFDTE 394 Query: 316 RESIMKEFRSGASRVLISTDVWARG--------LDVPQV-----------SLIINYDLPN 356 + + +++TD+ G +D + +I+ +P Sbjct: 395 ----YPKTKLTDWDFVVTTDISEMGANFRAGRVIDPRRCLKPVILTDGPERVILAGPIPV 450 Query: 357 NRELYIHRIGRSGR 370 R GR GR Sbjct: 451 TPASAAQRRGRIGR 464 >5EUL-A nrPDB Length = 836 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 54/140 (38%), Gaps = 14/140 (10%) Query: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAV 120 P +Q + + IA+ ++G GKT T ++ V + ++ LA Sbjct: 81 PFKVQLMG-GVALHDGN-IAEMKTGEGKTLTSTLPV---YLNALTGKGVHVVTVNEYLAS 135 Query: 121 QIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPG-------RVFDMIRR 173 + + + + +++ + + + +D ++ Y + T R ++ + Sbjct: 136 RDAEQMGKIFEFLGLTVGLNLNSMS--KDEKREAYAADITYSTNNELGFDYLRDNMVLYK 193 Query: 174 RSLRTRAIKMLVLDEADEML 193 + R + V+DE D +L Sbjct: 194 EQMVQRPLHFAVIDEVDSIL 213 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 23/140 (16%), Positives = 56/140 (40%), Gaps = 10/140 (7%) Query: 275 LTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST 334 +T ++ + +++ ++ ++ ++E + I + + GA V I+T Sbjct: 427 MTGQPVLVGTVAVETSELISKLLKNKGIPHQVLNAKNHEREAQIIEEAGQKGA--VTIAT 484 Query: 335 DVWARGLDVPQVS--------LIINYDLPNNRELYIHRIGRSGRYGRKGVAINFVKNDDI 386 ++ RG D+ ++ + +R + GRSGR G G+ ++ +D Sbjct: 485 NMAGRGTDIKLGEGVKELGGLAVVGTERHESRRIDNQLRGRSGRQGDPGITQFYLSMEDE 544 Query: 387 RILRDIEQYYSTQIDEMPMN 406 + R + +D M+ Sbjct: 545 LMRRFGAERTMAMLDRFGMD 564 >1Z5Z-A nrPDB Length = 271 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 47/106 (44%), Gaps = 3/106 (2%) Query: 276 TITQAVIFCNTKRKVDWLTEKM-REANFTVSSMHGDMPQKERESIMKEFRSGASR--VLI 332 + IF + + +E N V ++G++ +KER+ I+ +F++ S +++ Sbjct: 111 EGDKIAIFTQFVDMGKIIRNIIEKELNTEVPFLYGELSKKERDDIISKFQNNPSVKFIVL 170 Query: 333 STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVAI 378 S G+++ + +I++D N + R R G+ I Sbjct: 171 SVKAGGFGINLTSANRVIHFDRWWNPAVEDQATDRVYRIGQTRNVI 216 >5GN1-A nrPDB Length = 366 Score = 41.9 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 32/199 (16%), Positives = 67/199 (33%), Gaps = 16/199 (8%) Query: 219 ATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEW----KFDTLCDLYDT 274 A + E + M+ + + + + +EW K D L L T Sbjct: 138 AYAENGNKEYIKEDMSYMTDFELHKLCCNFPNTLSKY-QLHNDEWMQSGKIDALKKLLKT 196 Query: 275 LTITQ---AVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGA-SRV 330 + + + +IF + +D L + ++ + G +R+ ++ +F + Sbjct: 197 IIVDKQEKVLIFSLFTQVLDILEMVLSTLDYKFLRLDGSTQVNDRQLLIDKFYEDKDIPI 256 Query: 331 LI-STDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGV--AINFVKNDDIR 387 I ST G+++ + +I +D N R+ R G+ + D I Sbjct: 257 FILSTKAGGFGINLVCANNVIIFDQSFNPHDDRQAADRAHRVGQTKEVNITTLITKDSIE 316 Query: 388 I----LRDIEQYYSTQIDE 402 L + + I E Sbjct: 317 EKIHQLAKNKLALDSYISE 335 >2QEQ-A nrPDB Length = 434 Score = 41.9 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 46/311 (14%), Positives = 98/311 (31%), Gaps = 68/311 (21%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT +++ + R + +LAPTR +A ++ + L + Sbjct: 12 GAGKTRRILPQIIK--EAINRRLRTAVLAPTRVVAAEMAEALR------GLPIRYQTSAV 63 Query: 145 NVGEDIRKL-DYGQHVVAGTPGRVFDMIRRRSLRTRAI---KMLVLDEADEMLNKGFKEQ 200 + ++ D H T + R + + + V+DEA F + Sbjct: 64 AREHNGNEIVDVMCH---AT-------LTHRLMSPHRVPNYNLFVMDEAH------FTDP 107 Query: 201 IYDVYRYLPPATQVVLISATLPHEILEMTNKFMT--DPIRILVKRDELTLEGIKQFFVAV 258 + +T+V E+ E FMT P + Q + Sbjct: 108 -ASIAARGYISTRV---------ELGEAAAIFMTATPPGTSDPFPESNAPISDLQTEIPD 157 Query: 259 EREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERES 318 ++ + + I + V F + + + + ++ A V ++ + E Sbjct: 158 RAWNSGYEWITEY-----IGKTVWFVPSVKMGNEIALCLQRAGKKVIQLNRKSYETE--- 209 Query: 319 IMKEFRSGASRVLISTDVWARGLDVPQVSLI-----------------INYDLPN--NRE 359 + ++ +++TD+ G + +I + P+ Sbjct: 210 -YPKCKNDDWDFVVTTDISEMGANFKASRVIDSRKSVKPTIITEGEGRVILGEPSAVTAA 268 Query: 360 LYIHRIGRSGR 370 R GR+GR Sbjct: 269 SAAQRRGRTGR 279 >4QQW-A nrPDB Length = 964 Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 49/257 (19%), Positives = 86/257 (33%), Gaps = 68/257 (26%) Query: 182 KMLVLDEADEM--LNKGFKEQIYDVYRYLPPATQVVLISATLPHEILE-MTNKFMT---- 234 K++V+DEA + + EQ+ L VVL+SATL H I + ++ Sbjct: 466 KVVVVDEAHAVDPYMQVLLEQLLRWLGTL--DVPVVLLSATLHHSIANSLVKAYLEGARG 523 Query: 235 ------DPIRIL-------------------------VKRDELTLEGIKQFFVAVEREEW 263 +P + + + ++ V V +E Sbjct: 524 RRWNRSEPQPVSEVSYPGWLHVDARIGKVTRSSDVDPLPIATTPRKPLEVRLVDVPVKEG 583 Query: 264 KFDTLCDLYDTL-----TITQAVIFCNTKRKVDWLTEKMREANFTVSS-------MHGDM 311 + L L A I C T + + + + + T+ +H Sbjct: 584 ALNRSTVLAKELTPLVKQGGCAAIICTTVAEAQGVYDLLSQWFATLGEDAPDLYLLHSRF 643 Query: 312 PQKERES----IMKEF---------RSGASRVLISTDVWARGLDVPQVSLIINYDLPNNR 358 P ++R I+ F R VL++T V + LD+ V L+I+ P + Sbjct: 644 PNRQRTEITATIVDLFGKEGAQSGRRPTRGAVLVATQVVEQSLDL-DVDLMISDLAPVSL 702 Query: 359 ELYIHRIGRSGRYGRKG 375 + R GR R+ G Sbjct: 703 L--LQRAGRCWRHEHLG 717 >4UAQ-A nrPDB Length = 778 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 43/127 (33%), Gaps = 17/127 (13%) Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIS 333 ++ + + L E++ ++ +E I + + GA V +S Sbjct: 439 HQRGQPVLVGTRDVAESEELHERLVRRGVPAVVLNAKNDAEEARVIAEAGKYGA--VTVS 496 Query: 334 TDVWARGLDVP-----QVSL----------IINYDLPNNRELYIHRIGRSGRYGRKGVAI 378 T + RG D+ + ++ + L GR+GR G G ++ Sbjct: 497 TQMAGRGTDIRLGGSDEADHDRVAELGGLHVVGTGRHHTERLDNQLRGRAGRQGDPGSSV 556 Query: 379 NFVKNDD 385 F +D Sbjct: 557 FFSSWED 563 >1RIF-A nrPDB Length = 282 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 48/126 (38%), Gaps = 8/126 (6%) Query: 65 QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQK 124 Q+ A+ + + R I + G++ ++ L ++ E + LI+ PT L Q+ Sbjct: 118 QKDAVFEGLVNRRRILNLPTSAGRSLIQAL--LARYYLENYEGKILIIVPTTALTTQMAD 175 Query: 125 GLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKML 184 + + + GG + + K VV GT V +++ M+ Sbjct: 176 DFVDYRLFSHAMIKKIGGGASKDD---KYKNDAPVVVGTWQTV---VKQPKEWFSQFGMM 229 Query: 185 VLDEAD 190 + DE Sbjct: 230 MNDECH 235 >1NLZ-A nrPDB Length = 330 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 41/92 (44%), Gaps = 8/92 (8%) Query: 54 YAYGFEKPSAIQQRAIKQIIKG----RDVIAQSQSGTGKTATFSISVLQCLDIQVRETQA 109 GF +++AI I G ++VI +G+GKT T+ S+++ + +E + Sbjct: 146 EEQGFYNLLDNKEQAISAIKDGIAIGKNVIVCGGTGSGKT-TYIKSIMEFI---PKEERI 201 Query: 110 LILAPTRELAVQIQKGLLALGDYMNVQCHACI 141 + + T E+ + K L N+ C+ Sbjct: 202 ISIEDTEEIVFKHHKNYTQLFFGGNITSADCL 233 >1NL3-A nrPDB Length = 922 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 25/142 (17%), Positives = 52/142 (36%), Gaps = 14/142 (9%) Query: 59 EKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTREL 118 ++P +Q + G +A+ ++G GKT T + + I+ L Sbjct: 110 QRPFDVQVMGAAALHLGN--VAEMKTGEGKTLTCVLPA---YLNALAGNGVHIVTVNDYL 164 Query: 119 AVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV-FDMIRRRSLR 177 A + + + + ++ +Q + D R++ Y + GT FD +R Sbjct: 165 AKRDSEWMGRVHRFLGLQVGVILATMTP--DERRVAYNADITYGTNNEFGFDYLRDNMAH 222 Query: 178 -TRAI-----KMLVLDEADEML 193 + ++DE D +L Sbjct: 223 SLDDLVQRGHHYAIVDEVDSIL 244 Score = 31.1 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 29/65 (44%), Gaps = 2/65 (3%) Query: 279 QAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWA 338 +I + + ++L+ + + + ++ ++E I R G V ++T++ Sbjct: 462 PVLIGTTSVERSEYLSRQFTKRRIPHNVLNAKYHEQEATIIAVAGRRG--GVTVATNMAG 519 Query: 339 RGLDV 343 RG D+ Sbjct: 520 RGTDI 524 >2V6J-A nrPDB Length = 431 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 49/315 (15%), Positives = 100/315 (31%), Gaps = 79/315 (25%) Query: 85 GTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACIGGT 144 G GKT + L + + + +ILAPTR +A + + L G+ + A Sbjct: 12 GAGKTRR-VLPQLVR-EAVKKRLRTVILAPTRVVASETYEALR--GEPIRYMTPAV---- 63 Query: 145 NVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKML--------VLDEAD-----E 191 + T + D + + + ++ + ++DEA Sbjct: 64 ----QSER----------TGNEIVDFMCHSTFTMKLLQGVRVPNYNLYIMDEAHFLDPAS 109 Query: 192 MLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGI 251 + +G+ E R + ++AT P P + +E + Sbjct: 110 VAARGYIET-----RVSMGDAGAIFMTATPPGTTEAF------PPSNSPIIDEETRIPD- 157 Query: 252 KQFFVAVEREEWKFDTLCDLYDTLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDM 311 EW + + V F ++ ++ + +++A V ++ Sbjct: 158 ---KAWNSGYEWITE---------FDGRTVWFVHSIKQGAEIGTCLQKAGKKVLYLNRKT 205 Query: 312 PQKERESIMKEFRSGASRVLISTDVWARGLDVPQVSLI--------INYDLPNNRELYI- 362 + E + +S +I+TD+ G + +I I D + + I Sbjct: 206 FESE----YPKCKSEKWDFVITTDISEMGANFKADRVIDPRKTIKPILLDGRVSMQGPIA 261 Query: 363 -------HRIGRSGR 370 R GR GR Sbjct: 262 ITPASAAQRRGRIGR 276 >6FWS-A nrPDB Length = 716 Score = 37.6 bits (86), Expect = 0.009, Method: Composition-based stats. Identities = 13/48 (27%), Positives = 27/48 (56%), Gaps = 4/48 (8%) Query: 74 KGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQ 121 +GR + ++ +G GKT ++ I + I E + L+++ T +A+Q Sbjct: 46 EGRHLAIEAPTGVGKTLSYLIPG---IAIAREEQKTLVVS-TANVALQ 89 >5K9T-A nrPDB Length = 578 Score = 37.6 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 22/134 (16%), Positives = 48/134 (35%), Gaps = 12/134 (8%) Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 + + ++ IA+ ++G GKT T ++ + ++ LA + + Sbjct: 75 QLLGGMVLNERCIAEMRTGEGKTLTATLPA---YLNALTGKGVHVVTVNDYLAQRDAENN 131 Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV-FDMIRRR------SLRTR 179 L +++ + + G Y + GT FD +R + R Sbjct: 132 RPLFEFLGLTVGINLPGMPAPAKREA--YAADITYGTNNEYGFDYLRDNMAFSPAARVQR 189 Query: 180 AIKMLVLDEADEML 193 + ++DE D +L Sbjct: 190 KLHYALVDEVDSIL 203 >2FSI-A nrPDB Length = 853 Score = 36.9 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 22/134 (16%), Positives = 47/134 (35%), Gaps = 12/134 (8%) Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 + + ++ IA+ ++G GKT T ++ + ++ LA + + Sbjct: 79 QLLGGMVLNERCIAEMRTGEGKTLTATLPA---YLNALTGKGVHVVTVNDYLAQRDAENN 135 Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV-FDMIRRRSL------RTR 179 L +++ + + G Y + GT FD +R R Sbjct: 136 RPLFEFLGLTVGINLPGMPAPAKREA--YAADITYGTNNEYGFDYLRDNMAFSPEERVQR 193 Query: 180 AIKMLVLDEADEML 193 + ++DE D +L Sbjct: 194 KLHYALVDEVDSIL 207 >1Z3I-X nrPDB Length = 644 Score = 36.9 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 43/107 (40%), Gaps = 3/107 (2%) Query: 274 TLTITQAVIFCNTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSG---ASRV 330 T T + V+ N + +D + R + + G M K+R I++ F + Sbjct: 413 TTTSDKVVLVSNYTQTLDLFEKLCRNRRYLYVRLDGTMSIKKRAKIVERFNNPSSPEFIF 472 Query: 331 LISTDVWARGLDVPQVSLIINYDLPNNRELYIHRIGRSGRYGRKGVA 377 ++S+ GL++ + ++ +D N + R R G+K Sbjct: 473 MLSSKAGGCGLNLIGANRLVMFDPDWNPANDEQAMARVWRDGQKKTC 519 >5H8W-A nrPDB Length = 597 Score = 36.5 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 82 SQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQCHACI 141 S +G+GKT S LQ R+ + L L T Q+ K L +L M ++ Sbjct: 11 SPTGSGKTIMALKSALQY--SSERKLKVLYLVRTNSQEEQVIKELRSLSSTMKIRAIPMQ 68 Query: 142 G 142 G Sbjct: 69 G 69 >2FZ4-A nrPDB Length = 237 Score = 36.5 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 33/68 (48%), Gaps = 6/68 (8%) Query: 65 QQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQK 124 Q++A+++ + + +G+GKT +++ + L LI+ PT LA Q ++ Sbjct: 98 QEKALERWLVDKRGCIVLPTGSGKTHV-AMAAINELSTP-----TLIVVPTLALAEQWKE 151 Query: 125 GLLALGDY 132 L G+ Sbjct: 152 RLGIFGEE 159 >3CRV-A nrPDB Length = 551 Score = 34.5 bits (78), Expect = 0.074, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 39/87 (44%), Gaps = 10/87 (11%) Query: 60 KPSAIQQRAIKQIIKG--RDVIAQ--SQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115 K Q++ ++I+G + + + +G+GKT FS+ L L++ + + L + T Sbjct: 3 KLRDWQEKLKDKVIEGLRNNFLVALNAPTGSGKTL-FSL--LVSLEV---KPKVLFVVRT 56 Query: 116 RELAVQIQKGLLALGDYMNVQCHACIG 142 I + L + + N+ +G Sbjct: 57 HNEFYPIYRDLTKIREKRNITFSFLVG 83 >3A2B-A nrPDB Length = 398 Score = 34.5 bits (78), Expect = 0.082, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 42/111 (37%), Gaps = 12/111 (10%) Query: 196 GFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFF 255 GF DV +L + V+ SA++ + T K + +++ + +E Sbjct: 250 GFVAGDADVIDFLKHNARSVMFSASMTPASVASTLKALE-----IIQNEPEHIEK----- 299 Query: 256 VAVEREEWKFDTLCDLYDTLTITQAV--IFCNTKRKVDWLTEKMREANFTV 304 + + K L +D + IF + K W+T+ +++ V Sbjct: 300 LWKNTDYAKAQLLDHGFDLGATESPILPIFIRSNEKTFWVTKMLQDDGVFV 350 >5TV4-A nrPDB Length = 605 Score = 32.2 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 42/239 (17%), Positives = 69/239 (28%), Gaps = 47/239 (19%) Query: 1 MATTATMATSGSARKRLLKEEDMTKVEFETSEEVDVTPTFDTMGLREDLLRGIYAYGFEK 60 MA T+ T + + K+E +E T + TF G LR I Sbjct: 335 MAACQTLFTILDSEQE--KDEGKRVIERATGDVEFRNVTFTYPGRDVPALRNINLK---- 388 Query: 61 PSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISV----------------LQCLDIQV 104 I G+ V +SG+GK+ S+ L+ + Sbjct: 389 --------IPA---GKTVALVGRSGSGKSTIASLITRFYDIDEGEILMDGHDLREYTLAS 437 Query: 105 RETQALILAPTRELAVQI------QKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQH 158 Q +++ L + + I K+D G Sbjct: 438 LRNQVALVSQNVHLFNDTVANNIAYARTEQYSREQIEEAARMAYAMDF---INKMDNGLD 494 Query: 159 VVAGTPGRVFDMIRRRSLR-----TRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT 212 V G G + +R+ + R +L+LDEA L+ + I L Sbjct: 495 TVIGENGVLLSGGQRQRIAIARALLRDSPILILDEATSALDTESERAIQAALDELQKNR 553 >5O6D-A nrPDB Length = 545 Score = 31.8 bits (71), Expect = 0.62, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 49/152 (32%), Gaps = 23/152 (15%) Query: 62 SAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQ 121 S Q+ IK G ++ +GTGK+ +++ L + A T A Sbjct: 3 SKEQESIIKLAENGHNIFYTGSAGTGKSI-LLREMIKVLKGIYGRENVAVTASTGLAACN 61 Query: 122 IQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAI 181 I + H+ G D KL R+ R I Sbjct: 62 IG----------GITIHSFAGIGLGKGDADKLYKKV-----------RRSRKHLRRWENI 100 Query: 182 KMLVLDEADEMLNKGFKEQIYDVYRYLPPATQ 213 LV+DE ML+ +++ + R + Q Sbjct: 101 GALVVDEI-SMLDAELLDKLDFIARKIRKNHQ 131 >6D00-1 nrPDB Length = 883 Score = 31.1 bits (69), Expect = 0.86, Method: Composition-based stats. Identities = 22/163 (13%), Positives = 50/163 (30%), Gaps = 32/163 (19%) Query: 65 QQRAIKQI----------IKGRD-----VIAQSQSGTGKTATFSISVLQCLDIQVRETQA 109 Q AIK I ++ R+ + +G GKT V + + A Sbjct: 575 QDEAIKAICDAIRLSRTGLQNRNRPLASFLFLGPTGCGKTLC----VKELAAFLFNDPGA 630 Query: 110 LILAPTRELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDI-RKLDYGQHVVAGTPGRVF 168 ++ + + + + V G + G + + + V +F Sbjct: 631 IV-------RIDMSEYMEKHAVSRLVGAPPGYIGHDEGGQLTEAVRRRPYTVV-----LF 678 Query: 169 DMIRRRSLRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPA 211 D + + + + +LD+ +KG + + + Sbjct: 679 DEMEKAHKDVSNLLLQILDDGHCTDSKGRRVDFKNTIIVMTSN 721 >2V1U-A nrPDB Length = 387 Score = 31.1 bits (69), Expect = 0.93, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 50/131 (38%), Gaps = 28/131 (21%) Query: 66 QRAIKQIIKGR---DVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQI 122 + ++G + + +GTGKTA + VL+ L+ + L+ P A Sbjct: 32 AEVLAPALRGEKPSNALLYGLTGTGKTAVARL-VLRRLEARASSLGVLV-KPIYVNARHR 89 Query: 123 ---QKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTR 179 + A+ + + V+ G +VGE +L +R R R Sbjct: 90 ETPYRVASAIAEAVGVRVP--FTGLSVGEVYERL------------------VKRLSRLR 129 Query: 180 AIKMLVLDEAD 190 I ++VLDE D Sbjct: 130 GIYIIVLDEID 140 >5FL3-A nrPDB Length = 368 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 26/62 (41%), Gaps = 19/62 (30%) Query: 35 DVTPTFDTMGLREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGK--TATF 92 +V P+F+ +GL +++ + A +R + ++ +G+GK T Sbjct: 110 EVIPSFEALGLPREVMESLAAK---------ERGL--------ILVTGPTGSGKSTTLAA 152 Query: 93 SI 94 I Sbjct: 153 LI 154 >4I5O-A nrPDB Length = 363 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 12/82 (14%), Positives = 29/82 (35%), Gaps = 1/82 (1%) Query: 77 DVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQ 136 +++ +G+GKT ++ + LD+ A L + ++ + L + Sbjct: 53 NILLIGPTGSGKTLLAE-TLARLLDVPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYD 111 Query: 137 CHACIGGTNVGEDIRKLDYGQH 158 G ++I K+ Sbjct: 112 VQKAQRGIVYIDEIDKISRKSD 133 >1UB3-A nrPDB Length = 220 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 4/103 (3%) Query: 45 LREDLLRGIYAYGFEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFS--ISVLQCLDI 102 + + +L+ I G+ P I + A I G D + S +G G +++L + Sbjct: 116 VPQAVLKVILETGYFSPEEIARLAEAAIRGGADFLKTS-TGFGPRGASLEDVALLVRVAQ 174 Query: 103 QVRETQALILAPTRELAVQIQK-GLLALGDYMNVQCHACIGGT 144 + +A RE A+++ K G LG V A GGT Sbjct: 175 GRAQVKAAGGIRDRETALRMLKAGASRLGTSSGVALVAGEGGT 217 >2IPC-A nrPDB Length = 997 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 51/137 (37%), Gaps = 15/137 (10%) Query: 67 RAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGL 126 + I + IA+ ++G GKT +++V L+ + ++ LA + + + Sbjct: 84 QLIGGAVLHEGKIAEMKTGEGKTLVATLAV--ALNALTGKGVHVVTVNDY-LARRDAEWM 140 Query: 127 LALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRV-FDMIRRRS------LRTR 179 + + + + E R+ Y V T + FD +R L R Sbjct: 141 GPVYRGLGLSVGVIQHASTPAE--RRKAYLADVTYVTNSELGFDYLRDNMAISPDQLVLR 198 Query: 180 A---IKMLVLDEADEML 193 + ++DE D +L Sbjct: 199 HDHPLHYAIIDEVDSIL 215 >5V8F-E nrPDB Length = 479 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 30/181 (16%), Positives = 60/181 (33%), Gaps = 18/181 (9%) Query: 77 DVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQ 136 ++I Q SGTGKT T L+ A+ L P EL V + L A+ + + Sbjct: 32 NLILQGYSGTGKTYT-----LKKYFNANPNLHAVWLEP-VEL-VSWKPLLQAIARTVQYK 84 Query: 137 CHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRRRSLRTRAIKMLVLDEADEM--LN 194 + ++ T ++ SL+ + L+LD D + L+ Sbjct: 85 LKTLYPNIPTTDYDPLQVEEPFLLVKT--LHNIFVQYESLQEKTCLFLILDGFDSLQDLD 142 Query: 195 KGFKEQIYDVYRYLPPATQV-VLISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQ 253 + + LP +++ + T+ + F+ + + + Sbjct: 143 AALFNKYIKLNELLPKDSKINIKFIYTM------LETSFLQRYSTHCIPTVMFPRYNVDE 196 Query: 254 F 254 Sbjct: 197 V 197 >3M6A-A nrPDB Length = 543 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 21/97 (21%), Positives = 33/97 (34%), Gaps = 13/97 (13%) Query: 117 ELAVQIQKGLLALGDYMNVQCHACIGGTNVGEDIRKLDYGQHVVAGTPGRVFDMIRR-RS 175 LA I K L +GG +IR V PGR+ +++ Sbjct: 123 SLAKSIAKSLGRKF------VRISLGGVRDESEIRGHRRTY--VGAMPGRIIQGMKKAGK 174 Query: 176 LRTRAIKMLVLDEADEMLNKGFKEQIYDVYRYLPPAT 212 L + +LDE D+M + + + L P Sbjct: 175 LNP----VFLLDEIDKMSSDFRGDPSSAMLEVLDPEQ 207 >6F5D-G nrPDB Length = 304 Score = 29.5 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 17/151 (11%), Positives = 47/151 (31%), Gaps = 8/151 (5%) Query: 217 ISATLPHEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLT 276 S P E M + + +E V ++ ++ + + + + Sbjct: 114 FSKLYPDEFRYGIINDMKESMHF--GYATFVIENA----YEVSKDADRYQVIFNRFVSAG 167 Query: 277 ITQAVIFC--NTKRKVDWLTEKMREANFTVSSMHGDMPQKERESIMKEFRSGASRVLIST 334 + + ++ + ++ + L + N + + Q E E ++++F + + + Sbjct: 168 VQRNAVYNIPSYEKWKEDLADAASSDNQKNRYLFANALQNEEEQLIRDFFDFHAALAVLN 227 Query: 335 DVWARGLDVPQVSLIINYDLPNNRELYIHRI 365 V L L+ N R Sbjct: 228 AVGENELSEQAARLVAVEGQLTNISSLQQRT 258 >4ZCF-C nrPDB Length = 970 Score = 29.5 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 80 AQSQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115 ++GTGKT T+ ++ L+ + +I+ PT Sbjct: 82 VSMETGTGKTYTYIKTIFD-LNKSFGINKFIIIVPT 116 >3ACB-A nrPDB Length = 181 Score = 29.1 bits (64), Expect = 3.2, Method: Composition-based stats. Identities = 18/71 (25%), Positives = 29/71 (40%), Gaps = 6/71 (8%) Query: 73 IKGRDVIAQSQ-SGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGD 131 I GRDVI TG T ++ + L+ AL+ P+R Q++ + LG Sbjct: 93 IHGRDVIVVEDIVDTGLTLSYLLDYLEARKPASVRVAALLSKPSR---RQVEVPIHYLG- 148 Query: 132 YMNVQCHACIG 142 ++ G Sbjct: 149 -FEIEDAYVYG 158 >4HZU-A nrPDB Length = 279 Score = 29.1 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 26/52 (50%) Query: 182 KMLVLDEADEMLNKGFKEQIYDVYRYLPPATQVVLISATLPHEILEMTNKFM 233 K+L+LDEA ML+ + ++ + R L + +IS T + ++ + Sbjct: 160 KILILDEATSMLDPQGRIEMLAIVRQLRQQQNLTVISITHDIDEAASADRVL 211 >4B3F-X nrPDB Length = 646 Score = 29.1 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 25/52 (48%), Gaps = 4/52 (7%) Query: 65 QQRAIKQIIKGRDV-IAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPT 115 Q+ A+ + +++ I GTGKT T +LQ + ++ L AP+ Sbjct: 194 QKEAVLFALSQKELAIIHGPPGTGKTTTVVEIILQAVKQGLK---VLCCAPS 242 >1UM8-A nrPDB Length = 376 Score = 28.4 bits (62), Expect = 5.4, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 31/79 (39%), Gaps = 1/79 (1%) Query: 77 DVIAQSQSGTGKTATFSISVLQCLDIQVRETQALILAPTRELAVQIQKGLLALGDYMNVQ 136 +++ +G+GKT ++ + LDI + + A L + ++ L L + Sbjct: 74 NILLIGPTGSGKTLMAQ-TLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWN 132 Query: 137 CHACIGGTNVGEDIRKLDY 155 G ++I K+ Sbjct: 133 VQKAQKGIVFIDEIDKISR 151 >3S1A-A nrPDB Length = 525 Score = 28.0 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 27/82 (32%), Gaps = 8/82 (9%) Query: 51 RGIYAYG--FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQ 108 + I E I + GR + SGTGKT FSI L I+ E Sbjct: 16 QAIAKMRTMIEGFDDISHGGLPI---GRSTLVSGTSGTGKTL-FSIQFLYNGIIEFDEPG 71 Query: 109 ALILAPTRELAVQIQKGLLALG 130 + E I K + G Sbjct: 72 VFVT--FEETPQDIIKNARSFG 91 >5ZQT-A nrPDB Length = 473 Score = 28.0 bits (61), Expect = 8.4, Method: Composition-based stats. Identities = 22/108 (20%), Positives = 38/108 (35%), Gaps = 24/108 (22%) Query: 130 GDYMNVQCHACIGGTNVG---------------EDIRKLDYGQHVVAGTPGRVFDMIRRR 174 GD + +GGTN + ++ H++ GT +FD I Sbjct: 66 GDEHGLFYALDLGGTNFRVIRVQLGGREKRVVSQQYEEVAIPPHLMVGTSMELFDFI--- 122 Query: 175 SLRTRAIKMLVLDEA-DEMLNKGFKEQIYDVYRYLPPATQVVLISATL 221 ++ V E D L +G + ++ + P Q + S TL Sbjct: 123 ---AAELESFVKTEGEDFHLPEGRQRELGFTFS--FPVHQTSISSGTL 165 >4TLD-A nrPDB Length = 253 Score = 28.0 bits (61), Expect = 8.5, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 27/82 (32%), Gaps = 8/82 (9%) Query: 51 RGIYAYG--FEKPSAIQQRAIKQIIKGRDVIAQSQSGTGKTATFSISVLQCLDIQVRETQ 108 + I E I + GR + SGTGKT FSI L I+ E Sbjct: 16 QAIAKMRTMIEGFDDISHGGLPI---GRSTLVSGTSGTGKTL-FSIQFLYNGIIEFDEPG 71 Query: 109 ALILAPTRELAVQIQKGLLALG 130 + E I K + G Sbjct: 72 VFVT--FEETPQDIIKNARSFG 91 >1SXJ-B nrPDB Length = 323 Score = 27.6 bits (60), Expect = 9.1, Method: Composition-based stats. Identities = 23/199 (11%), Positives = 64/199 (32%), Gaps = 37/199 (18%) Query: 182 KMLVLDEADEM-------LNKGFK------------EQIYDVYRYLPPATQVVLISATLP 222 K+++LDEAD M L + + Q + L ++ S Sbjct: 109 KIVILDEADSMTAGAQQALRRTMELYSNSTRFAFACNQSNKIIEPLQSQCAILRYSKLSD 168 Query: 223 HEILEMTNKFMTDPIRILVKRDELTLEGIKQFFVAVEREEWKFDTLCDLYDTLTITQAVI 282 ++L+ + + I ++ + T +G++ E + + + ++ Sbjct: 169 EDVLK---RLLQ---IIKLEDVKYTNDGLEAIIFTAEGD---MRQAINNLQSTVAGHGLV 219 Query: 283 FCNTKRKVDWLTEKMREAN---FTVSSMHGDMPQKERESIMKEFRSGASRVLISTDVWAR 339 D + + + + + ++ + ++ G S + I T + Sbjct: 220 ------NADNVFKIVDSPHPLIVKKMLLASNLEDSIQILRTDLWKKGYSSIDIVTTSFRV 273 Query: 340 GLDVPQVSLIINYDLPNNR 358 ++ QV + ++ Sbjct: 274 TKNLAQVKESVRLEMIKEI 292 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.145 0.385 Lambda K H 0.267 0.0442 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,193,271 Number of Sequences: 36641 Number of extensions: 619085 Number of successful extensions: 2714 Number of sequences better than 10.0: 172 Number of HSP's better than 10.0 without gapping: 204 Number of HSP's successfully gapped in prelim test: 68 Number of HSP's that attempted gapping in prelim test: 1992 Number of HSP's gapped (non-prelim): 366 length of query: 411 length of database: 10,336,785 effective HSP length: 99 effective length of query: 312 effective length of database: 6,709,326 effective search space: 2093309712 effective search space used: 2093309712 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.0 bits)