BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P38489 (217 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1ICR-A nrPDB 448 e-127 3HZN-A nrPDB 400 e-112 1V5Y-A nrPDB 113 6e-26 3QDL-A nrPDB 76 1e-14 2H0U-A nrPDB 60 7e-10 4EO3-A nrPDB 35 0.029 3BEM-A nrPDB 35 0.034 1ZCH-A nrPDB 32 0.25 2WZV-A nrPDB 30 0.64 1AK1-A nrPDB 30 0.70 3BM1-A nrPDB 30 0.73 1USY-C nrPDB 30 0.83 2C8J-A nrPDB 30 1.2 1NOX-A nrPDB 29 1.3 6MFV-A nrPDB 27 4.7 5YSR-A nrPDB 27 7.0 >1ICR-A nrPDB Length = 217 Score = 448 bits (1152), Expect = e-127, Method: Compositional matrix adjust. Identities = 217/217 (100%), Positives = 217/217 (100%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV Sbjct: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 Query: 61 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG 120 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG Sbjct: 61 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG 120 Query: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE Sbjct: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 Query: 181 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 217 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV Sbjct: 181 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 217 >3HZN-A nrPDB Length = 220 Score = 400 bits (1029), Expect = e-112, Method: Compositional matrix adjust. Identities = 192/217 (88%), Positives = 203/217 (93%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 MDI+SVAL+R+STKAFD SKKLT E+A++IKTLLQYSPSSTNSQPWHFIVASTEEGKARV Sbjct: 4 MDIVSVALQRYSTKAFDPSKKLTAEEADKIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 63 Query: 61 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG 120 AKSAAGNY FNERKMLDASHVVVFCAKTAMDD WL+ VVDQEDADGRFATPEAKAANDKG Sbjct: 64 AKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEDADGRFATPEAKAANDKG 123 Query: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 R+FFADMHR L DD +WMAKQVYLNVGNFLLGVAA+GLDAVPIEGFDA +LDAEFGLKE Sbjct: 124 RRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLDAVPIEGFDAEVLDAEFGLKE 183 Query: 181 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 217 KGYTSLVVVPVGHHSVEDFNA LPKSRLP TLTEV Sbjct: 184 KGYTSLVVVPVGHHSVEDFNAGLPKSRLPLETTLTEV 220 >1V5Y-A nrPDB Length = 217 Score = 113 bits (282), Expect = 6e-26, Method: Compositional matrix adjust. Identities = 70/206 (33%), Positives = 109/206 (52%), Gaps = 3/206 (1%) Query: 3 IISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAK 62 II R+++K +D SKK++ E + L+ S SS NSQPW FIV ++ K R+ Sbjct: 4 IIHDLENRYTSKKYDPSKKVSQEDLAVLLEALRLSASSINSQPWKFIVIESDAAKQRMHD 63 Query: 63 SAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRK 122 S A + FN+ + SHV++F K + +V+ + AD R + +AA + Sbjct: 64 SFANMHQFNQPHIKACSHVILFANKLSYTRDDYDVVLSKAVADKRITEEQKEAAFASFK- 122 Query: 123 FFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKG 182 F +++ + + W Q YL +GN L +A L +D+ +EG D +L F + KG Sbjct: 123 -FVELNCDENGEHKAWTKPQAYLALGNALHTLARLNIDSTTMEGIDPELLSEIFADELKG 181 Query: 183 YTSLVVVPVG-HHSVEDFNATLPKSR 207 Y V + +G HH ED+NA+LPKSR Sbjct: 182 YECHVALAIGYHHPSEDYNASLPKSR 207 >3QDL-A nrPDB Length = 210 Score = 75.9 bits (185), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 47/160 (29%), Positives = 82/160 (51%), Gaps = 9/160 (5%) Query: 9 KRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNY 68 +RHS K FD+ + + + E+I + + SPSS N+QPWHF++ + ++ K ++ AA +Y Sbjct: 15 ERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDKDLKKQI---AAHSY 71 Query: 69 VFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMH 128 FNE + AS ++V C+ + + + + A G +F M Sbjct: 72 -FNEEMIKSASALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNHSMQ 130 Query: 129 RKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFD 168 R + ++ +Q Y+ VG +GV+ +GLD+ I GFD Sbjct: 131 RLE-----SYILEQCYIAVGQICMGVSLMGLDSCIIGGFD 165 >2H0U-A nrPDB Length = 217 Score = 60.1 bits (144), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 54/223 (24%), Positives = 107/223 (47%), Gaps = 40/223 (17%) Query: 3 IISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAK 62 ++++ +R + K +D +++++ + E + + + +PSS +PW ++ E K + Sbjct: 6 VVALQHQRFAAKKYDPNRRISQKDWEALVEVGRLAPSSIGLEPWKMLLLKNERMKEDLKP 65 Query: 63 SAAGNYVFNERKMLDASHVVVFCAKTAM--DDVWLKLVVDQ-----EDADGRFATPEAKA 115 A G +F + ASH V++ A+ + D ++K V+ + D + RFA Sbjct: 66 MAWGA-LFG---LEGASHFVIYLARKGVTYDSDYVKKVMHEVKKRDYDTNSRFA------ 115 Query: 116 ANDKGRKFFADMHRKDLHDDAE-----WMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAA 170 + + D+ ++E W +KQ Y+ + N ++ A LG+D+ PIEG+D Sbjct: 116 ------QIIKNFQENDMKLNSERSLFDWASKQTYIQMANMMMAAAMLGIDSCPIEGYDQE 169 Query: 171 ILDAEFGLKEKGYTSL------VVVPVGHHSVEDFNATLPKSR 207 ++A L+EKGY + V+ G+ + E PK+R Sbjct: 170 KVEAY--LEEKGYLNTAEFGVSVMACFGYRNQE----ITPKTR 206 >4EO3-A nrPDB Length = 322 Score = 34.7 bits (78), Expect = 0.029, Method: Compositional matrix adjust. Identities = 37/149 (24%), Positives = 56/149 (37%), Gaps = 44/149 (29%) Query: 21 KLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKS-AAGNYVFNERKMLDAS 79 ++ E+ E + +PS N+QPW F+V EE ++ ++ GNY L A Sbjct: 161 RVPREELELLIKAAHLAPSCMNNQPWRFVVVDEEELLKKIHEALPGGNYWMKNAPALIAV 220 Query: 80 HVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWM 139 H ++D D A P+ R +F L D Sbjct: 221 H-------------------SKKDFDC--ALPD-------NRDYF-------LFDTG--- 242 Query: 140 AKQVYLNVGNFLLGVAALGLDAVPIEGFD 168 L VGN L+ +GL A P+ G+D Sbjct: 243 -----LAVGNLLVQATQMGLVAHPVAGYD 266 >3BEM-A nrPDB Length = 218 Score = 34.7 bits (78), Expect = 0.034, Method: Compositional matrix adjust. Identities = 41/197 (20%), Positives = 87/197 (44%), Gaps = 26/197 (13%) Query: 9 KRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNY 68 +R S F + +T E ++ L+ +PS+ N Q ++ ++ K ++ ++A G Y Sbjct: 22 ERRSASNFLSGHPITKEDLNEMFELVALAPSAFNLQHTKYVTVLDQDVKEKLKQAANGQY 81 Query: 69 VFNERKMLDASHV-VVFCAKTAMD---DVWLKL----VVDQEDADGRFATPEAKAANDKG 120 K++ +S V +V K A D++ L ++++++ D ++G Sbjct: 82 -----KVVSSSAVLLVLGDKQAYQQAADIYEGLKVLGILNKQEYD-HMVQDTVSFYENRG 135 Query: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 +F D+A + L+ F+L AA G D P+ GFDA + + + Sbjct: 136 EQF--------KRDEA---IRNASLSAMMFMLSAAAAGWDTCPMIGFDAEAVKRILNIDD 184 Query: 181 KGYTSLVVVPVGHHSVE 197 + + ++++ +G E Sbjct: 185 Q-FEVVMMITIGKEKTE 200 >1ZCH-A nrPDB Length = 255 Score = 31.6 bits (70), Expect = 0.25, Method: Compositional matrix adjust. Identities = 25/98 (25%), Positives = 46/98 (46%), Gaps = 10/98 (10%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 M+ + +L H + + + EQ +QI +Q +PSS N Q I +E K ++ Sbjct: 1 MNEVIKSLTDHRSIRSYTDEPVAQEQLDQIIEAVQSAPSSINGQQVTVITVQDKERKKKI 60 Query: 61 AKSAAGNYVFNERKMLDASHVVVFC-----AKTAMDDV 93 ++ A G ++ A ++FC AK A++D+ Sbjct: 61 SELAGGQPWIDQ-----APVFLLFCADFNRAKIALEDL 93 >2WZV-A nrPDB Length = 235 Score = 30.4 bits (67), Expect = 0.64, Method: Compositional matrix adjust. Identities = 18/51 (35%), Positives = 29/51 (56%), Gaps = 6/51 (11%) Query: 10 RHSTKAFDASKKLTPEQAEQ-IKTLLQYSPSSTNSQPWHFIVASTEEGKAR 59 R + +AF + PE+ + + L ++PS++N+QPWH V S G AR Sbjct: 26 RRAVRAFRPDE--VPEETMRAVFELAGHAPSNSNTQPWHVEVVS---GAAR 71 >1AK1-A nrPDB Length = 310 Score = 30.0 bits (66), Expect = 0.70, Method: Compositional matrix adjust. Identities = 22/71 (30%), Positives = 34/71 (47%), Gaps = 3/71 (4%) Query: 122 KFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEK 181 K F D + LH+ A+ +A+ V + +G + G P G D L + ++K Sbjct: 190 KEFGDPYPDQLHESAKLIAEGA--GVSEYAVGWQSEGNTPDPWLGPDVQDLTRDL-FEQK 246 Query: 182 GYTSLVVVPVG 192 GY + V VPVG Sbjct: 247 GYQAFVYVPVG 257 >3BM1-A nrPDB Length = 183 Score = 30.0 bits (66), Expect = 0.73, Method: Compositional matrix adjust. Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKAR 59 MD + + + R S A T EQ + I +P + QPWHF V EG+ R Sbjct: 1 MDALELLINRRSASRL-AEPAPTGEQLQNILRAGMRAPDHKSMQPWHFFVIEG-EGRER 57 >1USY-C nrPDB Length = 275 Score = 30.0 bits (66), Expect = 0.83, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 39/84 (46%), Gaps = 6/84 (7%) Query: 128 HRKDLHDDAE---WMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKG-- 182 HRK +++ W A VY G+ L+ LGL+ VP D ++ E ++ Sbjct: 61 HRKRYSPESQIKVWYADFVYRYSGSDLVAEYQLGLEKVPRNSLDDSLEVLEIIVESASEF 120 Query: 183 YTSLVVVPVGHHSV-EDFNATLPK 205 + V+V +GH + ED +PK Sbjct: 121 FEGPVIVEIGHTGLYEDLLKEIPK 144 >2C8J-A nrPDB Length = 311 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/69 (31%), Positives = 32/69 (46%), Gaps = 3/69 (4%) Query: 124 FADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGY 183 D + L++ A+++A+ V N+ +G + G P G D L E K GY Sbjct: 191 MGDPYPDQLNETADYIARGA--EVANYAVGWQSAGNTPDPWIGPDVQDLTRELNEK-YGY 247 Query: 184 TSLVVVPVG 192 TS V PVG Sbjct: 248 TSFVYAPVG 256 >1NOX-A nrPDB Length = 205 Score = 29.3 bits (64), Expect = 1.3, Method: Compositional matrix adjust. Identities = 59/214 (27%), Positives = 96/214 (44%), Gaps = 29/214 (13%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQ---YSPSSTNSQPWHFIVASTEEGK 57 +D + ALKR S + + K PE ++ +L+ +PS+ N QPW +V K Sbjct: 8 LDAKTAALKRRSIRRY--RKDPVPEGL--LREILEAALRAPSAWNLQPWRIVVVRDPATK 63 Query: 58 ARVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKL-VVDQEDADGRFATPEAKAA 116 R + AA F + + +A V+V A ++D L V G E + A Sbjct: 64 -RALREAA----FGQAHVEEAPVVLVLYAD--LEDALAHLDEVIHPGVQG-----ERREA 111 Query: 117 NDKG-RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAE 175 + ++ FA M ++ W + Q Y+ +G LL + A GL +VP+ GFD + A Sbjct: 112 QKQAIQRAFAAMGQEA---RKAWASGQSYILLGYLLLLLEAYGLGSVPMLGFDPERVRAI 168 Query: 176 FGLKEKGYTSLVVVPVGHHSVEDFNATLPKSRLP 209 GL + +V +G+ + E + P RLP Sbjct: 169 LGLPSRAAIPALVA-LGYPAEEGY----PSHRLP 197 >6MFV-A nrPDB Length = 653 Score = 27.3 bits (59), Expect = 4.7, Method: Composition-based stats. Identities = 35/144 (24%), Positives = 61/144 (42%), Gaps = 13/144 (9%) Query: 15 AFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNE-R 73 A + K +TPE+ ++ L P N I+ S+E K N++F E Sbjct: 173 AREKEKSMTPEEFAKLYKLTFGHPLMLN-----LILESSE--ILATGKDTVFNFLFEEVY 225 Query: 74 KMLDASHVVVFCAKTAMDDV----WLKLVVDQEDADGRFATPEAKAANDKGRKFFA-DMH 128 +ML+ + + D+ +K + D+ ++ + KG K+F DM Sbjct: 226 QMLNEEEKDLLSILSLFDEPIEYEGIKFLYDRNPFVPLYSLMKKGLIEKKGEKYFVHDMV 285 Query: 129 RKDLHDDAEWMAKQVYLNVGNFLL 152 R+ + + + K+VYL NFLL Sbjct: 286 REFVREVSNQEEKEVYLRHVNFLL 309 >5YSR-A nrPDB Length = 453 Score = 26.9 bits (58), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 34/61 (55%), Gaps = 4/61 (6%) Query: 123 FFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVP--IEGFDAAILDAEFGLKE 180 F A + D DD + +A Q+Y + +F +G A +G++ V +E + +LD +G+ + Sbjct: 157 FSARLQPNDTRDDVQSIAAQIYEGL-SFGVGDAVIGVNPVTDDVENL-SRVLDTIYGVID 214 Query: 181 K 181 K Sbjct: 215 K 215 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3HZN-A nrPDB 324 2e-89 1ICR-A nrPDB 322 6e-89 1V5Y-A nrPDB 261 1e-70 3QDL-A nrPDB 201 2e-52 2H0U-A nrPDB 196 4e-51 Sequences not found previously or not previously below threshold: 1NOX-A nrPDB 72 2e-13 3BEM-A nrPDB 66 1e-11 4EO3-A nrPDB 62 2e-10 1ZCH-A nrPDB 48 3e-06 2WZV-A nrPDB 43 1e-04 3N2S-A nrPDB 42 2e-04 3GFD-A nrPDB 39 0.002 5YAK-A nrPDB 38 0.003 3BM1-A nrPDB 36 0.009 2ISL-A nrPDB 33 0.12 6D8G-A nrPDB 31 0.36 4BN9-A nrPDB 31 0.42 1YWQ-A nrPDB 30 0.67 4QHR-A nrPDB 30 0.99 4DO5-A nrPDB 30 1.0 >3HZN-A nrPDB Length = 220 Score = 324 bits (830), Expect = 2e-89, Method: Composition-based stats. Identities = 192/217 (88%), Positives = 203/217 (93%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 MDI+SVAL+R+STKAFD SKKLT E+A++IKTLLQYSPSSTNSQPWHFIVASTEEGKARV Sbjct: 4 MDIVSVALQRYSTKAFDPSKKLTAEEADKIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 63 Query: 61 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG 120 AKSAAGNY FNERKMLDASHVVVFCAKTAMDD WL+ VVDQEDADGRFATPEAKAANDKG Sbjct: 64 AKSAAGNYTFNERKMLDASHVVVFCAKTAMDDAWLERVVDQEDADGRFATPEAKAANDKG 123 Query: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 R+FFADMHR L DD +WMAKQVYLNVGNFLLGVAA+GLDAVPIEGFDA +LDAEFGLKE Sbjct: 124 RRFFADMHRVSLKDDHQWMAKQVYLNVGNFLLGVAAMGLDAVPIEGFDAEVLDAEFGLKE 183 Query: 181 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 217 KGYTSLVVVPVGHHSVEDFNA LPKSRLP TLTEV Sbjct: 184 KGYTSLVVVPVGHHSVEDFNAGLPKSRLPLETTLTEV 220 >1ICR-A nrPDB Length = 217 Score = 322 bits (826), Expect = 6e-89, Method: Composition-based stats. Identities = 217/217 (100%), Positives = 217/217 (100%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV Sbjct: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARV 60 Query: 61 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG 120 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG Sbjct: 61 AKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKG 120 Query: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE Sbjct: 121 RKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKE 180 Query: 181 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 217 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV Sbjct: 181 KGYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTEV 217 >1V5Y-A nrPDB Length = 217 Score = 261 bits (667), Expect = 1e-70, Method: Composition-based stats. Identities = 71/214 (33%), Positives = 111/214 (51%), Gaps = 3/214 (1%) Query: 3 IISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAK 62 II R+++K +D SKK++ E + L+ S SS NSQPW FIV ++ K R+ Sbjct: 4 IIHDLENRYTSKKYDPSKKVSQEDLAVLLEALRLSASSINSQPWKFIVIESDAAKQRMHD 63 Query: 63 SAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRK 122 S A + FN+ + SHV++F K + +V+ + AD R + +AA + Sbjct: 64 SFANMHQFNQPHIKACSHVILFANKLSYTRDDYDVVLSKAVADKRITEEQKEAAFASFK- 122 Query: 123 FFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKG 182 F +++ + + W Q YL +GN L +A L +D+ +EG D +L F + KG Sbjct: 123 -FVELNCDENGEHKAWTKPQAYLALGNALHTLARLNIDSTTMEGIDPELLSEIFADELKG 181 Query: 183 YTSLVVVPVG-HHSVEDFNATLPKSRLPQNITLT 215 Y V + +G HH ED+NA+LPKSR +T Sbjct: 182 YECHVALAIGYHHPSEDYNASLPKSRKAFEDVIT 215 >3QDL-A nrPDB Length = 210 Score = 201 bits (510), Expect = 2e-52, Method: Composition-based stats. Identities = 49/192 (25%), Positives = 90/192 (46%), Gaps = 9/192 (4%) Query: 6 VALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAA 65 + +RHS K FD+ + + + E+I + + SPSS N+QPWHF++ + ++ K ++ AA Sbjct: 12 LLNERHSCKMFDSHYEFSSTELEEIAEIARLSPSSYNTQPWHFVMVTDKDLKKQI---AA 68 Query: 66 GNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFA 125 +Y FNE + AS ++V C+ + + + + A G +F Sbjct: 69 HSY-FNEEMIKSASALMVVCSLRPSELLPHGHYMQNLYPESYKVRVIPSFAQMLGVRFNH 127 Query: 126 DMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTS 185 M R + ++ +Q Y+ VG +GV+ +GLD+ I GFD + + Sbjct: 128 SMQRLE-----SYILEQCYIAVGQICMGVSLMGLDSCIIGGFDPLKVGEVLEERINKPKI 182 Query: 186 LVVVPVGHHSVE 197 ++ +G E Sbjct: 183 ACLIALGKRVAE 194 >2H0U-A nrPDB Length = 217 Score = 196 bits (499), Expect = 4e-51, Method: Composition-based stats. Identities = 54/228 (23%), Positives = 107/228 (46%), Gaps = 40/228 (17%) Query: 3 IISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAK 62 ++++ +R + K +D +++++ + E + + + +PSS +PW ++ E K + Sbjct: 6 VVALQHQRFAAKKYDPNRRISQKDWEALVEVGRLAPSSIGLEPWKMLLLKNERMKEDLKP 65 Query: 63 SAAGNYVFNERKMLDASHVVVFCAKTA--MDDVWLKLVVDQ-----EDADGRFATPEAKA 115 A G +F + ASH V++ A+ D ++K V+ + D + RFA Sbjct: 66 MAWGA-LFG---LEGASHFVIYLARKGVTYDSDYVKKVMHEVKKRDYDTNSRFA------ 115 Query: 116 ANDKGRKFFADMHRKDLHDDAE-----WMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAA 170 + + D+ ++E W +KQ Y+ + N ++ A LG+D+ PIEG+D Sbjct: 116 ------QIIKNFQENDMKLNSERSLFDWASKQTYIQMANMMMAAAMLGIDSCPIEGYDQE 169 Query: 171 ILDAEFGLKEKGYTSL------VVVPVGHHSVEDFNATLPKSRLPQNI 212 ++A L+EKGY + V+ G+ + E PK+R + Sbjct: 170 KVEAY--LEEKGYLNTAEFGVSVMACFGYRNQE----ITPKTRWKTEV 211 >1NOX-A nrPDB Length = 205 Score = 71.8 bits (174), Expect = 2e-13, Method: Composition-based stats. Identities = 53/213 (24%), Positives = 88/213 (41%), Gaps = 23/213 (10%) Query: 1 MDIISVALKRHSTKAF--DASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKA 58 +D + ALKR S + + D + +I +PS+ N QPW +V K Sbjct: 8 LDAKTAALKRRSIRRYRKDP---VPEGLLREILEAALRAPSAWNLQPWRIVVVRDPATKR 64 Query: 59 RVAKSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAAND 118 + ++A F + + +A V+V A L V+ R +A Sbjct: 65 ALREAA-----FGQAHVEEAPVVLVLYADLEDALAHLDEVIHPGVQGER-----REAQKQ 114 Query: 119 KGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGL 178 ++ FA M ++ W + Q Y+ +G LL + A GL +VP+ GFD + A GL Sbjct: 115 AIQRAFAAMGQEARK---AWASGQSYILLGYLLLLLEAYGLGSVPMLGFDPERVRAILGL 171 Query: 179 KEKGYTSLVVVPVGHHSVEDFNATLPKSRLPQN 211 + +V +G+ + E + P RLP Sbjct: 172 PSRAAIP-ALVALGYPAEEGY----PSHRLPLE 199 >3BEM-A nrPDB Length = 218 Score = 66.0 bits (159), Expect = 1e-11, Method: Composition-based stats. Identities = 36/204 (17%), Positives = 86/204 (42%), Gaps = 26/204 (12%) Query: 2 DIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVA 61 + + +R S F + +T E ++ L+ +PS+ N Q ++ ++ K ++ Sbjct: 15 EFTHLVNERRSASNFLSGHPITKEDLNEMFELVALAPSAFNLQHTKYVTVLDQDVKEKLK 74 Query: 62 KSAAGNYVFNERKMLDASHVVVFCAKTA--------MDDVWLKLVVDQEDADGRFATPEA 113 ++A G Y K++ +S V++ + + + ++++++ D Sbjct: 75 QAANGQY-----KVVSSSAVLLVLGDKQAYQQAADIYEGLKVLGILNKQEYD-HMVQDTV 128 Query: 114 KAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILD 173 ++G +F R + +A L+ F+L AA G D P+ GFDA + Sbjct: 129 SFYENRGEQF----KRDEAIRNAS-------LSAMMFMLSAAAAGWDTCPMIGFDAEAVK 177 Query: 174 AEFGLKEKGYTSLVVVPVGHHSVE 197 + ++ + ++++ +G E Sbjct: 178 RILNIDDQ-FEVVMMITIGKEKTE 200 >4EO3-A nrPDB Length = 322 Score = 62.2 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 34/177 (19%), Positives = 63/177 (35%), Gaps = 43/177 (24%) Query: 21 KLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNERKMLDASH 80 ++ E+ E + +PS N+QPW F+V EE ++ ++ G M +A Sbjct: 161 RVPREELELLIKAAHLAPSCMNNQPWRFVVVDEEELLKKIHEALPG----GNYWMKNAPA 216 Query: 81 VVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLHDDAEWMA 140 ++ +K D L D+ ++ Sbjct: 217 LIAVHSKKDFDCA--------------------------------------LPDNRDYFL 238 Query: 141 KQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSLVVVPVGHHSVE 197 L VGN L+ +GL A P+ G+D + + E + + ++ VG+ E Sbjct: 239 FDTGLAVGNLLVQATQMGLVAHPVAGYDPVKVKEILKIPED-HVLITLIAVGYLGDE 294 >1ZCH-A nrPDB Length = 255 Score = 47.9 bits (112), Expect = 3e-06, Method: Composition-based stats. Identities = 41/210 (19%), Positives = 73/210 (34%), Gaps = 33/210 (15%) Query: 2 DIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVA 61 ++I S +++ + + EQ +QI +Q +PSS N Q I +E K +++ Sbjct: 3 EVIKSLTDHRSIRSY-TDEPVAQEQLDQIIEAVQSAPSSINGQQVTVITVQDKERKKKIS 61 Query: 62 KSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGR 121 + A G + + A ++FCA D A + +D Sbjct: 62 ELAGG-----QPWIDQAPVFLLFCA------------------DFNRAKIALEDLHDFKM 98 Query: 122 KFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEK 181 + + + A + +G +LGL VPI + L+ Sbjct: 99 EITNGLESVLVG------AVDAGIALGTATAAAESLGLGTVPIGAVRGNPQELIELLELP 152 Query: 182 GYTSLVVVPVGHHSVEDFNATLPKSRLPQN 211 Y + V H + + K RLPQ Sbjct: 153 KYVFPLSGLVIGHPAD---RSAKKPRLPQE 179 >2WZV-A nrPDB Length = 235 Score = 42.9 bits (99), Expect = 1e-04, Method: Composition-based stats. Identities = 39/205 (19%), Positives = 80/205 (39%), Gaps = 12/205 (5%) Query: 10 RHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYV 69 R + +AF ++ E + L ++PS++N+QPWH V S + R+A++ + Sbjct: 26 RRAVRAFRPD-EVPEETMRAVFELAGHAPSNSNTQPWHVEVVSG-AARDRLAEALVTAHA 83 Query: 70 FNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHR 129 + +F + R T + N + +F+ H Sbjct: 84 EERVTVDFPYREGLFQGVLQERRADFGSRLYAALGIARDQTDLLQGYNTESLRFYGAPHV 143 Query: 130 KDL---HDDAEWMAKQVYLNVGNFLLGVAALGLDAVP--IEGFDAAILDAEFGLKEKGYT 184 L ++ +A + + +L + A G+ + P + F A + AE G++ + Sbjct: 144 AMLFAPNNTEARIAGDMGIYAQTLMLAMTAHGIASCPQALLSFYADTVRAELGVENRKL- 202 Query: 185 SLVVVPVGHHSVEDFNATLPKSRLP 209 L+ + G+ D A + R+P Sbjct: 203 -LMGISFGY---ADDTAAVNGVRIP 223 >3N2S-A nrPDB Length = 249 Score = 42.1 bits (97), Expect = 2e-04, Method: Composition-based stats. Identities = 41/215 (19%), Positives = 70/215 (32%), Gaps = 33/215 (15%) Query: 2 DIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVA 61 + I L S ++F + LT E+ + + Q + +S+ Q + I S E K ++ Sbjct: 3 NTIETILNHRSIRSF-TDQLLTAEEIDTLVKSAQAASTSSYVQAYSIIGVSDPEKKRELS 61 Query: 62 KSAAGNYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGR 121 A N+ + H VFCA L Q + A +KG Sbjct: 62 VLAG-----NQPYVEKNGHFFVFCA---------DLYRHQ------------QLAEEKGE 95 Query: 122 KFFADMHRKDLHDDAEWMAKQVYLNVGNFLLGVAALGLDAVPIEGFDAAILDAEFGLKEK 181 + ++ + L N + ++GL I G + L+ Sbjct: 96 HISELLENTEMFMVS---LIDAALAAQNMSIAAESMGLGICYIGGIRNELDKVTEVLQTP 152 Query: 182 GYTSLVVVPVGHHSVEDFNATLPKSRLPQNITLTE 216 V+ G N + K RLP+ E Sbjct: 153 ---DHVLPLFGLAVGHPANLSGKKPRLPKQAVYHE 184 >3GFD-A nrPDB Length = 259 Score = 39.0 bits (89), Expect = 0.002, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 37/96 (38%), Gaps = 3/96 (3%) Query: 7 ALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAG 66 L + + F +S+ + E E + +PS +++PW F+V + K ++ + Sbjct: 60 LLNKRRSVRFISSEHVPMEVIENVIKAAGTAPSGAHTEPWTFVVVKDPDMKHKIREIIEE 119 Query: 67 NYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQE 102 N K + V + W+K +D Sbjct: 120 EEEINYMKRMGKRWVT---DLKKLRTNWIKEYLDTA 152 >5YAK-A nrPDB Length = 264 Score = 38.3 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 38/96 (39%), Gaps = 3/96 (3%) Query: 7 ALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAG 66 L + + F +++++ E + + +PS +++PW F+V + K ++ K Sbjct: 65 LLNKRRSVRFISNEQVPMEVIDNVIRTAGTAPSGAHTEPWTFVVVKDPDVKHKIRKIIEE 124 Query: 67 NYVFNERKMLDASHVVVFCAKTAMDDVWLKLVVDQE 102 N M H V + W+K +D Sbjct: 125 EEEIN--YMKRMGHRWV-TDLKKLRTNWIKEYLDTA 157 >3BM1-A nrPDB Length = 183 Score = 36.3 bits (82), Expect = 0.009, Method: Composition-based stats. Identities = 19/59 (32%), Positives = 26/59 (44%), Gaps = 2/59 (3%) Query: 1 MDIISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKAR 59 MD + + + R S A T EQ + I +P + QPWHF V E G+ R Sbjct: 1 MDALELLINRRSASRL-AEPAPTGEQLQNILRAGMRAPDHKSMQPWHFFVIEGE-GRER 57 >2ISL-A nrPDB Length = 230 Score = 32.9 bits (73), Expect = 0.12, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 22/43 (51%) Query: 22 LTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSA 64 L+ E ++ +PS QPW+F++ +E + +V ++ Sbjct: 45 LSEELIARLLGAAHQAPSVGFMQPWNFVLVRQDETREKVWQAF 87 >6D8G-A nrPDB Length = 886 Score = 31.3 bits (69), Expect = 0.36, Method: Composition-based stats. Identities = 24/129 (18%), Positives = 48/129 (37%), Gaps = 4/129 (3%) Query: 14 KAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKARVAKSAAGNYVFNER 73 +AFD S + + E +L+ +P W+FI S+ + + V+ +R Sbjct: 541 RAFDFSIEYQQKYLEHYLPVLEDTPYICGGTHWNFIDFSSALRDESMPRINNKGLVYADR 600 Query: 74 KMLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPEAKAANDKGRKFFADMHRKDLH 133 D H + D+ + + ++ D R + A K + ++ +L Sbjct: 601 TPKDVYHYYQAAWRK---DIPVLHIASRDWTD-RAGVQQGNAPVYLPVKIYTNLSEVELF 656 Query: 134 DDAEWMAKQ 142 D + KQ Sbjct: 657 IDGISLGKQ 665 >4BN9-A nrPDB Length = 201 Score = 30.9 bits (68), Expect = 0.42, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 24/52 (46%) Query: 4 ISVALKRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEE 55 I R + A + + + E IK +++SP++ NSQ ++ + + Sbjct: 3 IKSLENRRTIYALGRNVQDEEKVIETIKEAVRFSPTAFNSQTGRLLILTGDA 54 >1YWQ-A nrPDB Length = 200 Score = 30.2 bits (66), Expect = 0.67, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 22/50 (44%) Query: 9 KRHSTKAFDASKKLTPEQAEQIKTLLQYSPSSTNSQPWHFIVASTEEGKA 58 R S + + +T E+ E++ ++P+S N Q +V E + Sbjct: 14 NRRSIRKVTKNDAITKERIEEVLKTALHAPTSFNMQSGRMVVLMDGEHEK 63 >4QHR-A nrPDB Length = 356 Score = 29.8 bits (65), Expect = 0.99, Method: Composition-based stats. Identities = 22/129 (17%), Positives = 42/129 (32%), Gaps = 17/129 (13%) Query: 75 MLDASHVVVFCAKTAMDDVWLKLVVDQEDADGRFATPE-AKAANDKGRKFFADMHRKDLH 133 + + V C + ++ L +G F+ E A K + + Sbjct: 49 LNASDAFGVACLQEGLEIRELGFEQPVTLIEGVFSEDEMPVAIEQKFECVIHHQQQFEWL 108 Query: 134 DDAEWMAKQVYLNVG-----NFLLGVAALGLDAVPIEGFDAAILDAEFGLKEKGYTSLVV 188 KQ Y+ G G+ LG D I++ LK +G+T ++ Sbjct: 109 IKH----KQAYIAQGLKVWVKLNSGMNRLGFK-------DPEIIEVIKTLKSEGFTCVLA 157 Query: 189 VPVGHHSVE 197 + + V+ Sbjct: 158 MHFANADVD 166 >4DO5-A nrPDB Length = 400 Score = 29.8 bits (65), Expect = 1.0, Method: Composition-based stats. Identities = 10/65 (15%), Positives = 27/65 (41%), Gaps = 9/65 (13%) Query: 113 AKAANDKGRKFFADMHRKDLHDDAEWMAKQVYLNVGNFL-------LGVAALGLDAVPIE 165 +F +++ + D +++Q+++ + + + +G L +D I Sbjct: 9 PPMGWLAWERFRCNINCDE--DPKNCISEQLFMEMADRMAQDGWRDMGYTYLNIDDCWIG 66 Query: 166 GFDAA 170 G DA+ Sbjct: 67 GRDAS 71 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.121 0.303 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 7,103,975 Number of Sequences: 36641 Number of extensions: 240946 Number of successful extensions: 691 Number of sequences better than 10.0: 20 Number of HSP's better than 10.0 without gapping: 29 Number of HSP's successfully gapped in prelim test: 13 Number of HSP's that attempted gapping in prelim test: 643 Number of HSP's gapped (non-prelim): 45 length of query: 217 length of database: 10,336,785 effective HSP length: 93 effective length of query: 124 effective length of database: 6,929,172 effective search space: 859217328 effective search space used: 859217328 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 57 (26.7 bits)