BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P38132 (845 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5U8S-7 nrPDB 1746 0.0 3JC6-4 nrPDB 368 e-102 4R7Y-A nrPDB 346 2e-95 4FDG-B nrPDB 333 2e-91 3F9V-A nrPDB 325 5e-89 5BK4-5 nrPDB 324 9e-89 3JC7-2 nrPDB 320 2e-87 5XF8-3 nrPDB 283 3e-76 4R7Z-A nrPDB 233 2e-61 3F8T-A nrPDB 96 5e-20 1MKY-A nrPDB 33 0.48 1G8P-A nrPDB 33 0.70 2VEO-A nrPDB 32 0.85 5GQY-A nrPDB 32 1.1 3DZD-A nrPDB 31 2.0 3M6A-A nrPDB 31 2.9 2XSR-A nrPDB 30 3.5 1OFI-A nrPDB 30 4.4 4YPN-A nrPDB 30 6.1 3N37-A nrPDB 29 7.0 4QHS-A nrPDB 29 7.2 >5U8S-7 nrPDB Length = 845 Score = 1746 bits (4522), Expect = 0.0, Method: Compositional matrix adjust. Identities = 845/845 (100%), Positives = 845/845 (100%) Query: 1 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG 60 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG Sbjct: 1 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG 60 Query: 61 PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA 120 PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA Sbjct: 61 PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA 120 Query: 121 IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA 180 IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA Sbjct: 121 IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA 180 Query: 181 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT 240 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT Sbjct: 181 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT 240 Query: 241 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM 300 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM Sbjct: 241 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM 300 Query: 301 STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY 360 STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY Sbjct: 301 STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY 360 Query: 361 TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP 420 TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP Sbjct: 361 TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP 420 Query: 421 EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG 480 EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG Sbjct: 421 EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG 480 Query: 481 VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV 540 VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV Sbjct: 481 VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV 540 Query: 541 MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM 600 MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM Sbjct: 541 MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM 600 Query: 601 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV 660 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV Sbjct: 601 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV 660 Query: 661 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV Sbjct: 661 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 Query: 721 RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS 780 RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS Sbjct: 721 RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS 780 Query: 781 NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI 840 NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI Sbjct: 781 NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI 840 Query: 841 DLQDA 845 DLQDA Sbjct: 841 DLQDA 845 >3JC6-4 nrPDB Length = 933 Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust. Identities = 219/561 (39%), Positives = 335/561 (59%), Gaps = 44/561 (7%) Query: 227 VRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTS 286 +R++ + + +LI ++G++ R + V P ++V + C+ C + + E++ + C Sbjct: 314 MRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCER 373 Query: 287 EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPG 346 +C N+ + R S F+ Q K+QE VP G P S+++ V LV S G Sbjct: 374 IDC--NEPNSMSLIHNRCS-FADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAG 430 Query: 347 DIVDVTGIFLPAPYTGF---KALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVM- 402 D ++VTG F P + LK+ L +TY++ V++ K TS +E+ +M Sbjct: 431 DRIEVTGTFRSIPIRANSRQRVLKS--LYKTYVDVVHVKKVSDKRLDVD-TSTIEQELMQ 487 Query: 403 -----------------------ELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGG 439 E+ D+Y+ LA+SIAP IY DVKK +LL L GG Sbjct: 488 NKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGG 547 Query: 440 VDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMK 499 +K G + RGDIN+ L GDP +KSQ+L+ + KI+PRGVYT+GKGSS VGLTA + + Sbjct: 548 TNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITR 607 Query: 500 DPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNA 559 D T +++LE GALVL+D G+CCIDEFDKM +S R+ +HEVMEQQTISI+KAGI TTLNA Sbjct: 608 DVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNA 667 Query: 560 RTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYV 619 R+SILA+ANP+ RYNP L +NI+LP LLSRFD+++L+LD +D +LA+H+T + Sbjct: 668 RSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNL 727 Query: 620 HMHNKQPDL---DFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQ--DSKR 673 ++ +K + D PVE M YI+YAK P+++EA +V+AY+ +R+ D R Sbjct: 728 YLEDKPEHISQDDVLPVEFLTM--YISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSR 785 Query: 674 EMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNK 733 + + + AT R L +IRL++A AK++L ++V+++DV+EA+RL+R + + + Sbjct: 786 SDEKRIT---ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKT 842 Query: 734 SKEDESPTTKIFTIIKKMLQE 754 K D + ++I++ LQE Sbjct: 843 GKIDMNLVQTGKSVIQRKLQE 863 >4R7Y-A nrPDB Length = 613 Score = 346 bits (888), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 216/609 (35%), Positives = 339/609 (55%), Gaps = 18/609 (2%) Query: 124 NMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDTTMDPPSSMNDA 180 ++ +P+K+IDY+D ++ + + N+ +R NE+ R ++L+ D S N+ Sbjct: 1 SLEIPSKQIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDV-LSFNEN 59 Query: 181 LREVVEDETELFPPNLTRR---YFLYFKPLSQNCARRYRKKAIS-SKPLSVRQIKGDFLG 236 L + + T++ P L + L P Q + + + + + +R+I+ +G Sbjct: 60 LAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIG 119 Query: 237 QLITVRGIITRVSDVKPAVEVIAY--TCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQT 294 +LIT+ GI+ +V+ VK + Y C E F+ + E + C + Sbjct: 120 KLITIDGILVKVTPVKERIYKATYKHIHPDCMQE-FEWPEDEEMPEVLEMPTI-CPKCGK 177 Query: 295 KGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGI 354 GQ + +K +Q+ IQE ++VP G +PR L I + LV S PGD V VTGI Sbjct: 178 PGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGI 237 Query: 355 FLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRL 414 + K + + Y++ + +K ++ + E+ + EL D+ + + Sbjct: 238 LDIKQDSPVKRGSRAVF-DIYMKVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAI 296 Query: 415 AKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAIC 474 SIAP IYG +VKK + L L GGV +++ DG ++RGDI+V L+GDPGVAKSQ+L+ + Sbjct: 297 VDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVA 356 Query: 475 KISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDR 534 ++PR +YT+GK SS GLTAA ++D T +LE GALVLAD G IDE DKM + DR Sbjct: 357 NLAPRAIYTSGKSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDR 416 Query: 535 TAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRF 594 + IHE +EQQTISISKAGI TLNART+++AAANP GR+N +P + I+LP LLSRF Sbjct: 417 SVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRF 476 Query: 595 DILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYA-KTKRPVMS 653 D++F+++D P D ++A H+ V + P E +R+YIAYA K PV+S Sbjct: 477 DLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHE--ILRKYIAYARKNIHPVIS 534 Query: 654 EAVNDYVVQAYIRLRQDSKREMDSKFSFG--QATPRTLLGIIRLSQALAKLRLADMVDID 711 E + + + Y+R+R+ K+ + T R L +IRLS+A A++RL+ +V + Sbjct: 535 EEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTRE 594 Query: 712 DVEEALRLV 720 D EA++L+ Sbjct: 595 DAREAIKLM 603 >4FDG-B nrPDB Length = 692 Score = 333 bits (853), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 226/657 (34%), Positives = 354/657 (53%), Gaps = 35/657 (5%) Query: 125 MPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDTTMDPPSSMNDAL 181 M +P+K+IDY+D ++ + + N+ +R NE+ R ++L+ D S N+ L Sbjct: 7 MEIPSKQIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDV-LSFNENL 65 Query: 182 REVVEDETELFPPNLTRR---YFLYFKPLSQNCARRYRKKAIS-SKPLSVRQIKGDFLGQ 237 + + T++ P L + L P Q + + + + + +R+I+ +G+ Sbjct: 66 AYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGK 125 Query: 238 LITVRGIITRVSDVKPAVEVIAY--TCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTK 295 LIT+ GI+ +V+ VK + Y C E F+ + E + C + Sbjct: 126 LITIDGILVKVTPVKERIYKATYKHIHPDCMQE-FEWPEDEEMPEVLEMPTI-CPKCGKP 183 Query: 296 GQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIF 355 GQ + +K +Q+ IQE ++VP G +PR L I + LV S PGD V VTGI Sbjct: 184 GQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGIL 243 Query: 356 LPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLA 415 + K + + Y++ + +K ++ + E+++ +L + +R+ Sbjct: 244 DIKQDSPVKRGSRAVF-DIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRII 302 Query: 416 KSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICK 475 SIAP IYG+ ++K+AL L L GGV K + D +IRGDI++ ++GDPG AKSQ+L+ I + Sbjct: 303 SSIAPSIYGHWELKEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISR 361 Query: 476 ISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRT 535 ++PR VYTTGKGS+ GLTAAV+++ T E LE GALVLAD GI IDE DKM + DR Sbjct: 362 VAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRV 421 Query: 536 AIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFD 595 AIHE MEQQT+SI+KAGI LNAR +++AA NP +GRY DNINLP +LSRFD Sbjct: 422 AIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFD 481 Query: 596 ILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYA-KTKRPVMSE 654 ++F++ D P D E LA ++ VH ++ ++ +R+YIAYA K P ++ Sbjct: 482 LIFILKDQPGEQDRE-LANYILDVHSGKSTKNI----IDIDTLRKYIAYARKYVTPKITS 536 Query: 655 AVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVE 714 + + ++ +R+ S DS TPR L +IR+S+A AK+ L V +D E Sbjct: 537 EAKNLITDFFVEMRKKSSETPDSPILI---TPRQLEALIRISEAYAKMALKAEVTREDAE 593 Query: 715 EALRLVRVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRL 771 A+ ++R+ ES+ + K D I TI+ TGK + E ++K + + Sbjct: 594 RAINIMRLFLESVGVDMESGKID------IDTIM------TGKPKSAREKMMKIIEI 638 >3F9V-A nrPDB Length = 595 Score = 325 bits (833), Expect = 5e-89, Method: Compositional matrix adjust. Identities = 213/607 (35%), Positives = 332/607 (54%), Gaps = 23/607 (3%) Query: 131 EIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDTTMDPPSSMNDALREVVED 187 +IDY+D ++ + + N+ +R NE+ R ++L+ D S N+ L + + Sbjct: 1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDV-LSFNENLAYEIIN 59 Query: 188 ETELFPPNLTRR---YFLYFKPLSQNCARRYRKKAIS-SKPLSVRQIKGDFLGQLITVRG 243 T++ P L + L P Q + + + + + +R+I+ +G+LIT+ G Sbjct: 60 NTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDG 119 Query: 244 IITRVSDVKPAVEVIAY--TCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMS 301 I+ +V+ VK + Y C E F+ + E + C + GQ + Sbjct: 120 ILVKVTPVKERIYKATYKHIHPDCMQE-FEWPEDEEMPEVLEMPTI-CPKCGKPGQFRLI 177 Query: 302 TRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYT 361 +K +Q+ IQE ++VP G +PR L I + LV S PGD V VTGI + Sbjct: 178 PEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDS 237 Query: 362 GFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPE 421 K + + Y++ + +K ++ + E+++ +L + +R+ SIAP Sbjct: 238 PVKRGSRAVF-DIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPS 296 Query: 422 IYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGV 481 IYG+ ++K+AL L L GGV K + D +IRGDI++ ++GDPG AKSQ+L+ I +++PR V Sbjct: 297 IYGHWELKEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAV 355 Query: 482 YTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVM 541 YTTGKGS+ GLTAAV+++ T E LE GALVLAD GI IDE DKM + DR AIHE M Sbjct: 356 YTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAM 415 Query: 542 EQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLML 601 EQQT+SI+KAGI LNAR +++AA NP +GRY DNINLP +LSRFD++F++ Sbjct: 416 EQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILK 475 Query: 602 DIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYA-KTKRPVMSEAVNDYV 660 D P D E LA ++ VH ++ ++ +R+YIAYA K P ++ + + Sbjct: 476 DQPGEQDRE-LANYILDVHSGKSTKNI----IDIDTLRKYIAYARKYVTPKITSEAKNLI 530 Query: 661 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 ++ +R+ S DS TPR L +IR+S+A AK+ L V +D E A+ ++ Sbjct: 531 TDFFVEMRKKSSETPDSPILI---TPRQLEALIRISEAYAKMALKAEVTREDAERAINIM 587 Query: 721 RVSKESL 727 R+ ES+ Sbjct: 588 RLFLESV 594 >5BK4-5 nrPDB Length = 775 Score = 324 bits (831), Expect = 9e-89, Method: Compositional matrix adjust. Identities = 201/554 (36%), Positives = 300/554 (54%), Gaps = 67/554 (12%) Query: 225 LSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEV------FQEVNSRTF 278 + +R + + + +++ + GII S + ++ C C + F + T Sbjct: 146 IPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTV 205 Query: 279 TPLSECTS----------------EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQV 322 + C S E +N + +SKF Q K+QE+ + V Sbjct: 206 SLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELV 265 Query: 323 PVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIF------------------------LPA 358 PVG +PR+L + + L + PG V + GI+ + Sbjct: 266 PVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIRT 325 Query: 359 PYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSI 418 PY +++ + T + + + T + EE ++L + +Y L SI Sbjct: 326 PYIKILGIQSDVETSSIWNSVTM-----------FTEEEEEEFLQLSRNPKLYEILTNSI 374 Query: 419 APEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISP 478 AP I+GN D+KKA++ LL+GG K + DGM++RGDINV L+GDPG AKSQLLK + K+SP Sbjct: 375 APSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSP 434 Query: 479 RGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIH 538 VYT+GKGSS GLTA+V +DP+T E LEGGA+VLAD G+ CIDEFDKM + DR AIH Sbjct: 435 IAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIH 494 Query: 539 EVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILF 598 E MEQQTISI+KAGI T LN+RTS+LAAANP+YGRY+ SP DNI+ +LSRFD++F Sbjct: 495 EAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIF 554 Query: 599 LMLDIPSRDDDEKLAEHVTYVH------MHNKQPDLDFTPVEPSKMREYIAYAKTK-RPV 651 ++ D + + D +A HV +H M N+Q + + + + KM+ YI Y + K P Sbjct: 555 IVKDDHNEERDISIANHVINIHTGNANAMQNQQEE-NGSEISIEKMKRYITYCRLKCAPR 613 Query: 652 MSEAVNDYVVQAYIRLR-QDSKREMDS-KFSFGQATPRTLLGIIRLSQALAKLRLADMVD 709 +S + + ++ +R Q E++S + S T R L IIR++++LAKL L+ + Sbjct: 614 LSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQ 673 Query: 710 IDDVEEALRLVRVS 723 V+EA+RL + S Sbjct: 674 ERHVDEAIRLFQAS 687 >3JC7-2 nrPDB Length = 868 Score = 320 bits (820), Expect = 2e-87, Method: Compositional matrix adjust. Identities = 200/552 (36%), Positives = 298/552 (53%), Gaps = 72/552 (13%) Query: 226 SVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECT 285 S+R+++ L L+ V G++TR + V P ++ + + C +CG P + + Sbjct: 305 SLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCG---------SILGPFFQDS 355 Query: 286 SEE-----CSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLV 340 +EE C+ ++KG ++ + + +Q +QE VP G +PR + + LV Sbjct: 356 NEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLV 415 Query: 341 RSLSPGDIVDVTGIFLPAPYTGFKALKAGL-LTETYLEAQFVRQHKKKFAS--------F 391 PG+ V+VTGI+ Y G K G + T +EA +++ + A+ F Sbjct: 416 DVSKPGEEVEVTGIY-KNNYDGNLNAKNGFPVFATIIEANSIKRREGNTANEGEEGLDVF 474 Query: 392 SLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIR 451 S T + E ++ + +++ S+AP IYG+ D+K A+ L GGV K V IR Sbjct: 475 SWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSIR 534 Query: 452 GDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGG 511 GDINV L+GDPG AKSQ+LK + K + R V+ TG+G+S VGLTA+V KDP+T E LEGG Sbjct: 535 GDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEGG 594 Query: 512 ALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLY 571 ALVLAD G+C IDEFDKM++ DRT+IHE MEQQ+ISISKAGI TTL AR SI+AAANP Sbjct: 595 ALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPNG 654 Query: 572 GRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNK------- 624 GRYN L N++L +LSRFDIL ++ D+ + DE+LA V H+ + Sbjct: 655 GRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDEDR 714 Query: 625 -----------------------------------QPDLDFTPVEPSKMREYIAYAKTK- 648 + + + +P+ + +YI YA+TK Sbjct: 715 EGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYARTKI 774 Query: 649 RPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMV 708 P + + D V + Y LR RE S SF T R L I+R++++ AK+RL++ V Sbjct: 775 YPKLHQMDMDKVSRVYADLR----RESISTGSF-PITVRHLESILRIAESFAKMRLSEFV 829 Query: 709 DIDDVEEALRLV 720 D++ A+++V Sbjct: 830 SSYDLDRAIKVV 841 >5XF8-3 nrPDB Length = 997 Score = 283 bits (723), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 170/438 (38%), Positives = 257/438 (58%), Gaps = 34/438 (7%) Query: 217 KKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQE---- 272 K + + LS R + L +L++V GI+T+ S V+P + + + G +++ Sbjct: 184 KGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDA 243 Query: 273 ---VNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPR 329 + +R TP T E+ N+ + ST F Q +QE+ + P G +PR Sbjct: 244 TTTLTTRIPTPAIYPT-EDTEGNKLTTEYGYST----FIDHQRITVQEMPEMAPAGQLPR 298 Query: 330 SLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGLLTET-----------YLEA 378 S+++ ++ LV PGD V+V G+F K+L AG + ++ L Sbjct: 299 SIDVILDDDLVDKTKPGDRVNVVGVF--------KSLGAGGMNQSNSNTLIGFKTLILGN 350 Query: 379 QFVRQHKKK--FASFSLTSDVEER-VMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLL 435 H + A+ + +D + R + +L D+++ L++S+AP IYG+ +KKA+LL+ Sbjct: 351 TVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLM 410 Query: 436 LVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTA 495 L+GGV+K + +G +RGDIN+ ++GDP AKSQLL+ + + + TTG+GSSGVGLTA Sbjct: 411 LMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTA 470 Query: 496 AVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINT 555 AV D T E LE GA+VLAD G+ CIDEFDKM + DR AIHEVMEQQT++I+KAGI+T Sbjct: 471 AVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHT 530 Query: 556 TLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEH 615 TLNAR S++AAANP++G+Y+ P NI LP +LLSRFD+LF++ D + D ++EH Sbjct: 531 TLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEH 590 Query: 616 VTYVHMHNKQPDLDFTPV 633 V H + L+ PV Sbjct: 591 VLRTHRYLPPGYLEGEPV 608 Score = 40.8 bits (94), Expect = 0.003, Method: Compositional matrix adjust. Identities = 30/87 (34%), Positives = 50/87 (57%), Gaps = 7/87 (8%) Query: 638 MREYIAYAKTKR-PVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLS 696 +R+Y+ YAK + P +++ + +V+ Y LR D ++K S T RTL +IRL+ Sbjct: 682 LRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDD----NTKKS--PITARTLETLIRLA 735 Query: 697 QALAKLRLADMVDIDDVEEALRLVRVS 723 A AK+RL+ V+ D + A L+R + Sbjct: 736 TAHAKVRLSKTVNKVDAKVAANLLRFA 762 >4R7Z-A nrPDB Length = 338 Score = 233 bits (595), Expect = 2e-61, Method: Compositional matrix adjust. Identities = 129/326 (39%), Positives = 190/326 (58%), Gaps = 5/326 (1%) Query: 398 EERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVC 457 E+ + EL D+ + + SIAP IYG +VKK + L L GGV +++ DG ++RGDI+V Sbjct: 5 EQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVL 64 Query: 458 LMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLAD 517 L+GDPGVAKSQ+L+ + ++PR +YT+ Sbjct: 65 LVGDPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 124 Query: 518 NGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPR 577 G IDE DKM + DR+ IHE +EQQTISISKAGI TLNART+++AAANP GR+N Sbjct: 125 GGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRM 184 Query: 578 LSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSK 637 +P + I+LP LLSRFD++F+++D P D ++A H+ V + P E Sbjct: 185 KNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHE--I 242 Query: 638 MREYIAYA-KTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFG--QATPRTLLGIIR 694 +R+YIAYA K PV+SE + + + Y+R+R+ K+ + T R L +IR Sbjct: 243 LRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALIR 302 Query: 695 LSQALAKLRLADMVDIDDVEEALRLV 720 LS+A A++RL+ +V +D EA++L+ Sbjct: 303 LSEAHARMRLSPIVTREDAREAIKLM 328 >3F8T-A nrPDB Length = 506 Score = 96.3 bits (238), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 94/324 (29%), Positives = 147/324 (45%), Gaps = 37/324 (11%) Query: 409 DVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQ 468 D A++IAP + G +V K L L L V K ++V L G P V Sbjct: 203 DPLTTFARAIAP-LPGAEEVGKMLALQLFSCVGKN-------SERLHVLLAGYPVVCSEI 254 Query: 469 LLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDK 528 L + ++PRGVY + + LTA + +D L GA VLAD GI +D + Sbjct: 255 LHHVLDHLAPRGVYVDLRRTELTDLTAVLKED---RGWALRAGAAVLADGGILAVDHLEG 311 Query: 529 MDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPA 588 E R A+ E M++ T+++ LNAR ++LAA NP G P P+ I+L Sbjct: 312 APEPHRWALMEAMDKGTVTVD----GIALNARCAVLAAINP--GEQWPSDPPIARIDLDQ 365 Query: 589 ALLSRFDIL-FLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKT 647 LS FD++ FL +D + +E+ E +Y + +R Y+ YA Sbjct: 366 DFLSHFDLIAFLGVDPRPGEPEEQDTEVPSY-----------------TLLRRYLLYAIR 408 Query: 648 KRPV--MSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLA 705 + P ++E + Y R++ + + T R L + RL++A A++RL+ Sbjct: 409 EHPAPELTEEARKRLEHWYETRREEVEERLGMGLPTLPVTRRQLESVERLAKAHARMRLS 468 Query: 706 DMVDIDDVEEALRLVRVSKESLYQ 729 D V+ +DV+ A LV E+ Q Sbjct: 469 DDVEPEDVDIAAELVDWYLETAMQ 492 >1MKY-A nrPDB Length = 439 Score = 33.1 bits (74), Expect = 0.48, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 27/66 (40%), Gaps = 10/66 (15%) Query: 454 INVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGAL 513 I V ++G P V KS L AI K + V +DPV DE+ ++G Sbjct: 181 IKVAIVGRPNVGKSTLFNAIL----------NKERALVSPIPGTTRDPVDDEVFIDGRKY 230 Query: 514 VLADNG 519 V D Sbjct: 231 VFVDTA 236 >1G8P-A nrPDB Length = 350 Score = 32.7 bits (73), Expect = 0.70, Method: Compositional matrix adjust. Identities = 50/210 (23%), Positives = 77/210 (36%), Gaps = 49/210 (23%) Query: 422 IYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGV 481 I G D+K ALLL VD +G V + GD G KS ++A+ + P Sbjct: 26 IVGQEDMKLALLLT---AVDPGIG---------GVLVFGDRGTGKSTAVRALAALLPEIE 73 Query: 482 YTTG------------------------KGSSGVGLTAAVMKDPVTD-----------EM 506 G K + V L V +D V E Sbjct: 74 AVEGCPVSSPNVEMIPDWATVLSTNVIRKPTPVVDLPLGVSEDRVVGALDIERAISKGEK 133 Query: 507 ILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAA 566 E G L A+ G IDE + +++ + +V + + + G++ AR ++ + Sbjct: 134 AFEPGLLARANRGYLYIDECNLLEDHIVDLLLDVAQSGENVVERDGLSIRHPARFVLVGS 193 Query: 567 ANPLYGRYNPRLSPLDNINLPAALLSRFDI 596 NP G P+L LD L +LS D+ Sbjct: 194 GNPEEGDLRPQL--LDRFGLSVEVLSPRDV 221 >2VEO-A nrPDB Length = 441 Score = 32.3 bits (72), Expect = 0.85, Method: Compositional matrix adjust. Identities = 19/56 (33%), Positives = 30/56 (53%), Gaps = 9/56 (16%) Query: 746 TIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCIQEYSYLNVWHLINEGNTL 801 + I+ L G+ TL K +R RGF + Q+ + Y +LNV+ L+N+ N L Sbjct: 250 SFIEARLNAKGQQTL------KQIRGRGFCLPQV---VLTYPFLNVFSLVNDTNLL 296 >5GQY-A nrPDB Length = 793 Score = 32.0 bits (71), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 40/87 (45%), Gaps = 3/87 (3%) Query: 48 DAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQ-ADDLVSAI 106 + +N E H+ EK Y + N S+++D+D+I Q+ +E++L+ + +D L + Sbjct: 214 EIKNSEGHIYEKSDPYGFYREVRPNTA--SIVVDIDNIYQWHDEEWLEKRRNSDPLKQPV 271 Query: 107 QQNANHFTELFCRAIDNNMPLPTKEID 133 H + MPL E D Sbjct: 272 SVYEVHLGSWLHGSSAEKMPLLNGEAD 298 >3DZD-A nrPDB Length = 368 Score = 31.2 bits (69), Expect = 2.0, Method: Compositional matrix adjust. Identities = 29/126 (23%), Positives = 52/126 (41%), Gaps = 22/126 (17%) Query: 456 VCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVM-------------KDPV 502 V + G+ G K + + I + S G+ + V L A + K Sbjct: 155 VLITGESGTGKEIVARLIHRYS-------GRKGAFVDLNCASIPQELAESELFGHEKGAF 207 Query: 503 TDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTS 562 T + + G L LAD G +DE ++D+ + + V+E T S ++ G N + Sbjct: 208 TGALTRKKGKLELADQGTLFLDEVGELDQRVQAKLLRVLE--TGSFTRLGGNQKIEVDIR 265 Query: 563 ILAAAN 568 +++A N Sbjct: 266 VISATN 271 >3M6A-A nrPDB Length = 543 Score = 30.8 bits (68), Expect = 2.9, Method: Compositional matrix adjust. Identities = 44/155 (28%), Positives = 66/155 (42%), Gaps = 28/155 (18%) Query: 450 IRGDINVCLMGDPGVAKSQLLKAICK--------ISPRGVY----TTGKGSSGVGLTAAV 497 ++G I +CL G PGV K+ L K+I K IS GV G + VG Sbjct: 106 LKGPI-LCLAGPPGVGKTSLAKSIAKSLGRKFVRISLGGVRDESEIRGHRRTYVGAMPG- 163 Query: 498 MKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDR----TAIHEVME-QQTISISKAG 552 I++G N + +DE DKM R +A+ EV++ +Q S S Sbjct: 164 --------RIIQGMKKAGKLNPVFLLDEIDKMSSDFRGDPSSAMLEVLDPEQNSSFSDHY 215 Query: 553 INTTLN-ARTSILAAANPLYGRYNPRLSPLDNINL 586 I T + ++ +A AN L P ++ IN+ Sbjct: 216 IEETFDLSKVLFIATANNLATIPGPLRDRMEIINI 250 >2XSR-A nrPDB Length = 312 Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 627 DLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATP 686 DLD P E K EY+ A + A ++ Y+ LR D E D+K TP Sbjct: 49 DLDIQPSEVWKGLEYLTDAGQANELGLLAAG-LGLEHYLDLRAD---EADAKAGITGGTP 104 Query: 687 RTLLGIIRLSQALAKLRLADMVD 709 RT+ G + ++ A + A M D Sbjct: 105 RTIEGPLYVAGAPESVGFARMDD 127 >1OFI-A nrPDB Length = 310 Score = 30.0 bits (66), Expect = 4.4, Method: Compositional matrix adjust. Identities = 28/113 (24%), Positives = 53/113 (46%), Gaps = 6/113 (5%) Query: 422 IYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDI---NVCLMGDPGVAKSQLLKAICKISP 478 I G D K+A+ + L +R+ +R ++ N+ ++G GV K+++ + + K++ Sbjct: 17 IIGQADAKRAVAIALRNRW-RRMQLQEPLRHEVTPKNILMIGPTGVGKTEIARRLAKLAN 75 Query: 479 RG-VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGAL-VLADNGICCIDEFDKM 529 + + VG + + D GGA+ + NGI IDE DK+ Sbjct: 76 APFIKVEATKFTEVGYVGKEVDSIIRDLTDSAGGAIDAVEQNGIVFIDEIDKI 128 >4YPN-A nrPDB Length = 293 Score = 29.6 bits (65), Expect = 6.1, Method: Compositional matrix adjust. Identities = 43/178 (24%), Positives = 78/178 (43%), Gaps = 17/178 (9%) Query: 423 YGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINV-CLMGDPGVAKSQLLKAICKISPRGV 481 YG DVK+ +L L +++ G+ +R + L+G PGV K+ L ++I + R Sbjct: 115 YGLKDVKERILEYLAV---RQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 171 Query: 482 YTTGKGSSGVGLTAAVMKDPVTDEMILEGGAL-----VLADNGICCIDEFDKMDESDR-- 534 + G GV A + T + G + V N + +DE DKM R Sbjct: 172 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGD 229 Query: 535 --TAIHEVME-QQTISISKAGINTTLN-ARTSILAAANPLYGRYNPRLSPLDNINLPA 588 +A+ EV++ +Q + + ++ + ++ + AN L P L ++ I +P Sbjct: 230 PASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQTIPRPLLDRMEVIEIPG 287 >3N37-A nrPDB Length = 319 Score = 29.3 bits (64), Expect = 7.0, Method: Compositional matrix adjust. Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 8/60 (13%) Query: 60 GPKYMAMLQKVA---NRELNSVIIDL-----DDILQYQNEKFLQGTQADDLVSAIQQNAN 111 G KY ++K++ EL S DL D+ LQY +E + + ADD+ + + NAN Sbjct: 200 GYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNAN 259 >4QHS-A nrPDB Length = 267 Score = 29.3 bits (64), Expect = 7.2, Method: Compositional matrix adjust. Identities = 42/207 (20%), Positives = 81/207 (39%), Gaps = 31/207 (14%) Query: 453 DINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMIL--EG 510 D NV ++G G K + + I SPR K + + A + D + + + E Sbjct: 38 DANVMILGPSGSGKEVMSRYIHNASPR------KEGPFIAINCAAIPDNMLEATLFGYEK 91 Query: 511 GALV-----------LADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNA 559 GA A G +DE +MD + + + V++++ + + G ++ Sbjct: 92 GAFTGAVQACPGKFEQAQGGTILLDEISEMDLNLQAKLLRVLQER--EVERLGSRKSIKL 149 Query: 560 RTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLD--IPSRDDDEKLAEHVT 617 +LA +N +Y + + L R ++ L +DD E LA H+ Sbjct: 150 DVRVLATSNRDLKQY------VQAGHFREDLYYRLNVFPLTWPALCERKDDIEPLANHL- 202 Query: 618 YVHMHNKQPDLDFTPVEPSKMREYIAY 644 + H K+ L + P+ + + + Y Sbjct: 203 -IERHCKKLGLPVPSIAPNAITKLLNY 228 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5U8S-7 nrPDB 1270 0.0 4FDG-B nrPDB 848 0.0 4R7Y-A nrPDB 842 0.0 3F9V-A nrPDB 808 0.0 3JC6-4 nrPDB 608 e-174 3JC7-2 nrPDB 569 e-162 5BK4-5 nrPDB 560 e-159 5XF8-3 nrPDB 463 e-130 4R7Z-A nrPDB 416 e-116 3F8T-A nrPDB 357 1e-98 Sequences not found previously or not previously below threshold: 2R44-A nrPDB 43 5e-04 4QHS-A nrPDB 42 0.001 5EXX-A nrPDB 42 0.001 5EXS-A nrPDB 41 0.003 4LZZ-A nrPDB 40 0.006 1NY5-A nrPDB 39 0.007 3DZD-A nrPDB 39 0.007 3M6A-A nrPDB 39 0.007 4PEK-A nrPDB 39 0.011 4L4U-A nrPDB 38 0.015 1OFI-A nrPDB 36 0.054 4BS1-B nrPDB 36 0.077 4IJB-A nrPDB 35 0.15 1OJL-A nrPDB 35 0.16 5NZZ-A nrPDB 35 0.17 2POM-A nrPDB 35 0.17 1IN6-A nrPDB 35 0.19 1HQC-A nrPDB 35 0.19 4PA8-A nrPDB 34 0.23 2QJ0-A nrPDB 34 0.23 2C3Z-A nrPDB 34 0.26 5W0T-A nrPDB 34 0.34 3NYZ-A nrPDB 34 0.36 3HOJ-A nrPDB 33 0.68 1QVR-A nrPDB 33 0.68 4YPN-A nrPDB 32 0.81 4YPL-A nrPDB 32 0.88 5AOU-A nrPDB 32 0.99 4I5O-A nrPDB 32 1.3 3UD6-A nrPDB 32 1.3 5C3C-A nrPDB 32 1.5 3UXA-A nrPDB 31 1.9 1UM8-A nrPDB 31 2.0 3K1J-A nrPDB 31 2.1 5GQY-A nrPDB 31 2.3 2ISS-A nrPDB 31 2.3 3N37-A nrPDB 31 2.4 4ZPX-A nrPDB 30 3.0 1RWG-A nrPDB 30 3.3 3TC6-A nrPDB 30 3.6 4V7Q-BX nrPDB 30 3.8 2D2N-C nrPDB 30 4.5 4HSE-A nrPDB 30 4.6 2Q58-A nrPDB 30 4.9 3U5Z-B nrPDB 30 5.0 4F8X-A nrPDB 30 5.2 3CRV-A nrPDB 30 5.3 4LJ8-A nrPDB 29 8.4 2Z4R-A nrPDB 29 8.8 >5U8S-7 nrPDB Length = 845 Score = 1270 bits (3285), Expect = 0.0, Method: Composition-based stats. Identities = 845/845 (100%), Positives = 845/845 (100%) Query: 1 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG 60 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG Sbjct: 1 MSAALPSIQLPVDYNNLFNEITDFLVTFKQDTLSSDATRNENEDENLDAENIEQHLLEKG 60 Query: 61 PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA 120 PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA Sbjct: 61 PKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADDLVSAIQQNANHFTELFCRA 120 Query: 121 IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA 180 IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA Sbjct: 121 IDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDA 180 Query: 181 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT 240 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT Sbjct: 181 LREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQIKGDFLGQLIT 240 Query: 241 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM 300 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM Sbjct: 241 VRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFM 300 Query: 301 STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY 360 STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY Sbjct: 301 STRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPY 360 Query: 361 TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP 420 TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP Sbjct: 361 TGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAP 420 Query: 421 EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG 480 EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG Sbjct: 421 EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRG 480 Query: 481 VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV 540 VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV Sbjct: 481 VYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEV 540 Query: 541 MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM 600 MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM Sbjct: 541 MEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLM 600 Query: 601 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV 660 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV Sbjct: 601 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYV 660 Query: 661 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV Sbjct: 661 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 Query: 721 RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS 780 RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS Sbjct: 721 RVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLS 780 Query: 781 NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI 840 NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI Sbjct: 781 NCIQEYSYLNVWHLINEGNTLKFVDDGTMDTDQEDSLVSTPKLAPQTTASANVSAQDSDI 840 Query: 841 DLQDA 845 DLQDA Sbjct: 841 DLQDA 845 >4FDG-B nrPDB Length = 692 Score = 848 bits (2191), Expect = 0.0, Method: Composition-based stats. Identities = 225/657 (34%), Positives = 354/657 (53%), Gaps = 35/657 (5%) Query: 125 MPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDTTMDPPSSMNDAL 181 M +P+K+IDY+D ++ + + N+ +R NE+ R ++L+ D S N+ L Sbjct: 7 MEIPSKQIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDV-LSFNENL 65 Query: 182 REVVEDETELFPPNLTRR---YFLYFKPLSQNCARRYRKKAIS-SKPLSVRQIKGDFLGQ 237 + + T++ P L + L P Q + + + + + +R+I+ +G+ Sbjct: 66 AYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGK 125 Query: 238 LITVRGIITRVSDVKPAVEVIAY--TCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTK 295 LIT+ GI+ +V+ VK + Y C E F+ + E + C + Sbjct: 126 LITIDGILVKVTPVKERIYKATYKHIHPDCMQE-FEWPEDEEMPEVLEMPTI-CPKCGKP 183 Query: 296 GQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIF 355 GQ + +K +Q+ IQE ++VP G +PR L I + LV S PGD V VTGI Sbjct: 184 GQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGIL 243 Query: 356 LPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLA 415 + K + + Y++ + +K ++ + E+++ +L + +R+ Sbjct: 244 DIKQDSPVKRGSRAVF-DIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRII 302 Query: 416 KSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICK 475 SIAP IYG+ ++K+AL L L GGV K + D +IRGDI++ ++GDPG AKSQ+L+ I + Sbjct: 303 SSIAPSIYGHWELKEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISR 361 Query: 476 ISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRT 535 ++PR VYTTGKGS+ GLTAAV+++ T E LE GALVLAD GI IDE DKM + DR Sbjct: 362 VAPRAVYTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRV 421 Query: 536 AIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFD 595 AIHE MEQQT+SI+KAGI LNAR +++AA NP +GRY DNINLP +LSRFD Sbjct: 422 AIHEAMEQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFD 481 Query: 596 ILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYA-KTKRPVMSE 654 ++F++ D P D +LA ++ VH ++ ++ +R+YIAYA K P ++ Sbjct: 482 LIFILKDQPGEQ-DRELANYILDVHSGKSTKNI----IDIDTLRKYIAYARKYVTPKITS 536 Query: 655 AVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVE 714 + + ++ +R+ S DS TPR L +IR+S+A AK+ L V +D E Sbjct: 537 EAKNLITDFFVEMRKKSSETPDSPIL---ITPRQLEALIRISEAYAKMALKAEVTREDAE 593 Query: 715 EALRLVRVSKESLYQETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRL 771 A+ ++R+ ES+ + K D I TI+ TGK + E ++K + + Sbjct: 594 RAINIMRLFLESVGVDMESGKID------IDTIM------TGKPKSAREKMMKIIEI 638 >4R7Y-A nrPDB Length = 613 Score = 842 bits (2174), Expect = 0.0, Method: Composition-based stats. Identities = 216/619 (34%), Positives = 343/619 (55%), Gaps = 18/619 (2%) Query: 124 NMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDTTMDPPSSMNDA 180 ++ +P+K+IDY+D ++ + + N+ +R NE+ R ++L+ D S N+ Sbjct: 1 SLEIPSKQIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDV-LSFNEN 59 Query: 181 LREVVEDETELFPPNLTRR---YFLYFKPLSQNCARRYRKKAIS-SKPLSVRQIKGDFLG 236 L + + T++ P L + L P Q + + + + + +R+I+ +G Sbjct: 60 LAYEIINNTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIG 119 Query: 237 QLITVRGIITRVSDVKPAVEVIAY--TCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQT 294 +LIT+ GI+ +V+ VK + Y C E F+ + E + C + Sbjct: 120 KLITIDGILVKVTPVKERIYKATYKHIHPDCMQE-FEWPEDEEMPEVLEMPTI-CPKCGK 177 Query: 295 KGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGI 354 GQ + +K +Q+ IQE ++VP G +PR L I + LV S PGD V VTGI Sbjct: 178 PGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGI 237 Query: 355 FLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRL 414 + K + + Y++ + +K ++ + E+ + EL D+ + + Sbjct: 238 LDIKQDSPVKRGSRAVF-DIYMKVSSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAI 296 Query: 415 AKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAIC 474 SIAP IYG +VKK + L L GGV +++ DG ++RGDI+V L+GDPGVAKSQ+L+ + Sbjct: 297 VDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVA 356 Query: 475 KISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDR 534 ++PR +YT+GK SS GLTAA ++D T +LE GALVLAD G IDE DKM + DR Sbjct: 357 NLAPRAIYTSGKSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDR 416 Query: 535 TAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRF 594 + IHE +EQQTISISKAGI TLNART+++AAANP GR+N +P + I+LP LLSRF Sbjct: 417 SVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRF 476 Query: 595 DILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYA-KTKRPVMS 653 D++F+++D P D ++A H+ V + P E +R+YIAYA K PV+S Sbjct: 477 DLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPHEI--LRKYIAYARKNIHPVIS 534 Query: 654 EAVNDYVVQAYIRLRQDSKREMDSKFSFG--QATPRTLLGIIRLSQALAKLRLADMVDID 711 E + + + Y+R+R+ K+ + T R L +IRLS+A A++RL+ +V + Sbjct: 535 EEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTRE 594 Query: 712 DVEEALRLVRVSKESLYQE 730 D EA++L+ + + + + Sbjct: 595 DAREAIKLMEYTLKQIAMD 613 >3F9V-A nrPDB Length = 595 Score = 808 bits (2086), Expect = 0.0, Method: Composition-based stats. Identities = 212/608 (34%), Positives = 332/608 (54%), Gaps = 23/608 (3%) Query: 131 EIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDTTMDPPSSMNDALREVVED 187 +IDY+D ++ + + N+ +R NE+ R ++L+ D S N+ L + + Sbjct: 1 QIDYRDVFIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDV-LSFNENLAYEIIN 59 Query: 188 ETELFPPNLTRR---YFLYFKPLSQNCARRYRKKAIS-SKPLSVRQIKGDFLGQLITVRG 243 T++ P L + L P Q + + + + + +R+I+ +G+LIT+ G Sbjct: 60 NTKIILPILEGALYDHILQLDPTYQRDIEKVHVRIVGIPRVIELRKIRSTDIGKLITIDG 119 Query: 244 IITRVSDVKPAVEVIAY--TCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQTKGQLFMS 301 I+ +V+ VK + Y C E F+ + E + C + GQ + Sbjct: 120 ILVKVTPVKERIYKATYKHIHPDCMQE-FEWPEDEEMPEVLEMPTI-CPKCGKPGQFRLI 177 Query: 302 TRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYT 361 +K +Q+ IQE ++VP G +PR L I + LV S PGD V VTGI + Sbjct: 178 PEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDS 237 Query: 362 GFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPE 421 K + + Y++ + +K ++ + E+++ +L + +R+ SIAP Sbjct: 238 PVKRGSRAVF-DIYMKVSSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPS 296 Query: 422 IYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGV 481 IYG+ ++K+AL L L GGV K + D +IRGDI++ ++GDPG AKSQ+L+ I +++PR V Sbjct: 297 IYGHWELKEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAV 355 Query: 482 YTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVM 541 YTTGKGS+ GLTAAV+++ T E LE GALVLAD GI IDE DKM + DR AIHE M Sbjct: 356 YTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAM 415 Query: 542 EQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLML 601 EQQT+SI+KAGI LNAR +++AA NP +GRY DNINLP +LSRFD++F++ Sbjct: 416 EQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILK 475 Query: 602 DIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIAYA-KTKRPVMSEAVNDYV 660 D P D +LA ++ VH ++ ++ +R+YIAYA K P ++ + + Sbjct: 476 DQPGEQ-DRELANYILDVHSGKSTKNI----IDIDTLRKYIAYARKYVTPKITSEAKNLI 530 Query: 661 VQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 ++ +R+ S DS TPR L +IR+S+A AK+ L V +D E A+ ++ Sbjct: 531 TDFFVEMRKKSSETPDSPIL---ITPRQLEALIRISEAYAKMALKAEVTREDAERAINIM 587 Query: 721 RVSKESLY 728 R+ ES+ Sbjct: 588 RLFLESVG 595 >3JC6-4 nrPDB Length = 933 Score = 608 bits (1567), Expect = e-174, Method: Composition-based stats. Identities = 236/705 (33%), Positives = 375/705 (53%), Gaps = 64/705 (9%) Query: 130 KEIDYKDDVLDVILNQRRLRNERMLSDRTNEIRS---ENL-MDTTMDPPSSMNDALREVV 185 K +D +++ ++ E + NE+R NL +D + L + Sbjct: 207 KILDEREEFINNTT-----DEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQL 261 Query: 186 EDETELFPPNLTRR-----YFLYFKPLSQNCARRYRKKAISSKPLS------VRQIKGDF 234 + + + + L K +P + +R++ + Sbjct: 262 LNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCKGMRELNPND 321 Query: 235 LGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEECSQNQT 294 + +LI ++G++ R + V P ++V + C+ C + + E++ + C +C N+ Sbjct: 322 IDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDC--NEP 379 Query: 295 KGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGI 354 + R S F+ Q K+QE VP G P S+++ V LV S GD ++VTG Sbjct: 380 NSMSLIHNRCS-FADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGT 438 Query: 355 FLPAPYTGFKALKA-GLLTETYLEAQFVRQHKKKFASFSLTSDVEE-------------- 399 F P + L +TY++ V++ K ++ +E Sbjct: 439 FRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEV 498 Query: 400 ---------RVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKI 450 ++ E+ D+Y+ LA+SIAP IY DVKK +LL L GG +K G + Sbjct: 499 RQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRY 558 Query: 451 RGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEG 510 RGDIN+ L GDP +KSQ+L+ + KI+PRGVYT+GKGSS VGLTA + +D T +++LE Sbjct: 559 RGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLES 618 Query: 511 GALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPL 570 GALVL+D G+CCIDEFDKM +S R+ +HEVMEQQTISI+KAGI TTLNAR+SILA+ANP+ Sbjct: 619 GALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPI 678 Query: 571 YGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDL-- 628 RYNP L +NI+LP LLSRFD+++L+LD +D +LA+H+T +++ +K + Sbjct: 679 GSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQ 738 Query: 629 -DFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQ--DSKREMDSKFSFGQA 684 D PVE M YI+YAK P+++EA +V+AY+ +R+ D R + + + A Sbjct: 739 DDVLPVEFLTM--YISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRIT---A 793 Query: 685 TPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTKI 744 T R L +IRL++A AK++L ++V+++DV+EA+RL+R + + + K D + Sbjct: 794 TTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTG 853 Query: 745 FTIIKKMLQETGKNTLSYE--NIVKTVRLRGFTMLQLSNCIQEYS 787 ++I++ LQE LS E N++K + +L I E+S Sbjct: 854 KSVIQRKLQE----DLSREIMNVLKDQASDSMSFNELIKQINEHS 894 >3JC7-2 nrPDB Length = 868 Score = 569 bits (1466), Expect = e-162, Method: Composition-based stats. Identities = 197/573 (34%), Positives = 297/573 (51%), Gaps = 73/573 (12%) Query: 206 PLSQNCARRYRKKAIS-SKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQ 264 P + S+R+++ L L+ V G++TR + V P ++ + + C + Sbjct: 284 PDYARIHSEIHVRISDFPTIYSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLK 343 Query: 265 CGYEVFQEVNSRTFTPLSECTSEE-----CSQNQTKGQLFMSTRASKFSAFQECKIQELS 319 CG P + ++EE C+ ++KG ++ + + +Q +QE Sbjct: 344 CG---------SILGPFFQDSNEEIRISFCTNCKSKGPFRVNGEKTVYRNYQRVTLQEAP 394 Query: 320 QQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAGL-LTETYLEA 378 VP G +PR + + LV PG+ V+VTGI+ Y G K G + T +EA Sbjct: 395 GTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGIY-KNNYDGNLNAKNGFPVFATIIEA 453 Query: 379 QFVRQHKKKFAS--------FSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKK 430 +++ + A+ FS T + E ++ + +++ S+AP IYG+ D+K Sbjct: 454 NSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKT 513 Query: 431 ALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSG 490 A+ L GGV K V IRGDINV L+GDPG AKSQ+LK + K + R V+ TG+G+S Sbjct: 514 AVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASA 573 Query: 491 VGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISK 550 VGLTA+V KDP+T E LEGGALVLAD G+C IDEFDKM++ DRT+IHE MEQQ+ISISK Sbjct: 574 VGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISK 633 Query: 551 AGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDE 610 AGI TTL AR SI+AAANP GRYN L N++L +LSRFDIL ++ D+ + DE Sbjct: 634 AGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADE 693 Query: 611 KLAEHVTYVHMHNKQ------------------------------------------PDL 628 +LA V H+ + + Sbjct: 694 RLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEE 753 Query: 629 DFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPR 687 + +P+ + +YI YA+TK P + + D V + Y LR++S T R Sbjct: 754 EISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRRESIST-----GSFPITVR 808 Query: 688 TLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 L I+R++++ AK+RL++ V D++ A+++V Sbjct: 809 HLESILRIAESFAKMRLSEFVSSYDLDRAIKVV 841 >5BK4-5 nrPDB Length = 775 Score = 560 bits (1442), Expect = e-159, Method: Composition-based stats. Identities = 203/584 (34%), Positives = 310/584 (53%), Gaps = 66/584 (11%) Query: 225 LSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEV------FQEVNSRTF 278 + +R + + + +++ + GII S + ++ C C + F + T Sbjct: 146 IPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTV 205 Query: 279 TPLSECTS----------------EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQV 322 + C S E +N + +SKF Q K+QE+ + V Sbjct: 206 SLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELV 265 Query: 323 PVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIF------------------------LPA 358 PVG +PR+L + + L + PG V + GI+ + Sbjct: 266 PVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIRT 325 Query: 359 PYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSI 418 PY +++ + T + + + T + EE ++L + +Y L SI Sbjct: 326 PYIKILGIQSDVETSSIWNSVTM-----------FTEEEEEEFLQLSRNPKLYEILTNSI 374 Query: 419 APEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISP 478 AP I+GN D+KKA++ LL+GG K + DGM++RGDINV L+GDPG AKSQLLK + K+SP Sbjct: 375 APSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSP 434 Query: 479 RGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIH 538 VYT+GKGSS GLTA+V +DP+T E LEGGA+VLAD G+ CIDEFDKM + DR AIH Sbjct: 435 IAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIH 494 Query: 539 EVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILF 598 E MEQQTISI+KAGI T LN+RTS+LAAANP+YGRY+ SP DNI+ +LSRFD++F Sbjct: 495 EAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIF 554 Query: 599 LMLDIPSRDDDEKLAEHVTYVHMHN-----KQPDLDFTPVEPSKMREYIAYAKTK-RPVM 652 ++ D + + D +A HV +H N Q + + + + KM+ YI Y + K P + Sbjct: 555 IVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRL 614 Query: 653 SEAVNDYVVQAYIRLRQD-SKREMDS-KFSFGQATPRTLLGIIRLSQALAKLRLADMVDI 710 S + + ++ +R+ E++S + S T R L IIR++++LAKL L+ + Sbjct: 615 SPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQE 674 Query: 711 DDVEEALRLVRVSKESLYQETNKSKEDESPTTKIFTIIKKMLQE 754 V+EA+RL + S + +++ T + + I++ QE Sbjct: 675 RHVDEAIRLFQASTMDAASQDPIGGLNQASGTSL-SEIRRFEQE 717 >5XF8-3 nrPDB Length = 997 Score = 463 bits (1192), Expect = e-130, Method: Composition-based stats. Identities = 166/430 (38%), Positives = 251/430 (58%), Gaps = 18/430 (4%) Query: 217 KKAISSKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQE---- 272 K + + LS R + L +L++V GI+T+ S V+P + + + G +++ Sbjct: 184 KGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDA 243 Query: 273 ---VNSRTFTPLSECTSEECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPR 329 + +R TP +E+ N+ + ST F Q +QE+ + P G +PR Sbjct: 244 TTTLTTRIPTPAIY-PTEDTEGNKLTTEYGYST----FIDHQRITVQEMPEMAPAGQLPR 298 Query: 330 SLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKAG---LLTETYLEAQFVRQHKK 386 S+++ ++ LV PGD V+V G+F G + L H + Sbjct: 299 SIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSNSNTLIGFKTLILGNTVYPLHAR 358 Query: 387 KF--ASFSLTSDVEER-VMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKR 443 A+ + +D + R + +L D+++ L++S+AP IYG+ +KKA+LL+L+GGV+K Sbjct: 359 STGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKN 418 Query: 444 VGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVT 503 + +G +RGDIN+ ++GDP AKSQLL+ + + + TTG+GSSGVGLTAAV D T Sbjct: 419 LENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRET 478 Query: 504 DEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSI 563 E LE GA+VLAD G+ CIDEFDKM + DR AIHEVMEQQT++I+KAGI+TTLNAR S+ Sbjct: 479 GERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSV 538 Query: 564 LAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHN 623 +AAANP++G+Y+ P NI LP +LLSRFD+LF++ D + D ++EHV H + Sbjct: 539 IAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYL 598 Query: 624 KQPDLDFTPV 633 L+ PV Sbjct: 599 PPGYLEGEPV 608 >4R7Z-A nrPDB Length = 338 Score = 416 bits (1070), Expect = e-116, Method: Composition-based stats. Identities = 129/340 (37%), Positives = 196/340 (57%), Gaps = 5/340 (1%) Query: 394 TSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGD 453 + + E+ + EL D+ + + SIAP IYG +VKK + L L GGV +++ DG ++RGD Sbjct: 1 SPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGD 60 Query: 454 INVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGAL 513 I+V L+GDPGVAKSQ+L+ + ++PR +YT+ Sbjct: 61 IHVLLVGDPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 120 Query: 514 VLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGR 573 G IDE DKM + DR+ IHE +EQQTISISKAGI TLNART+++AAANP GR Sbjct: 121 XXXXGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGR 180 Query: 574 YNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPV 633 +N +P + I+LP LLSRFD++F+++D P D ++A H+ V + P Sbjct: 181 FNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVVAPKIPH 240 Query: 634 EPSKMREYIAYA-KTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFG--QATPRTLL 690 E +R+YIAYA K PV+SE + + + Y+R+R+ K+ + T R L Sbjct: 241 EI--LRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLE 298 Query: 691 GIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQE 730 +IRLS+A A++RL+ +V +D EA++L+ + + + + Sbjct: 299 ALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAMD 338 >3F8T-A nrPDB Length = 506 Score = 357 bits (916), Expect = 1e-98, Method: Composition-based stats. Identities = 106/398 (26%), Positives = 163/398 (40%), Gaps = 55/398 (13%) Query: 345 PGDIVDVTGIFLPAPYTGFKALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMEL 404 PG V++ GI A + K K E EL Sbjct: 157 PGLRVEILGIVRSATLDALEVHK-----------------KDPIPEVHPDPAELEEFREL 199 Query: 405 ITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGV 464 D A++IAP + G +V K L L L V K ++V L G P V Sbjct: 200 A-DKDPLTTFARAIAP-LPGAEEVGKMLALQLFSCVGKN-------SERLHVLLAGYPVV 250 Query: 465 AKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCID 524 L + ++PRGVY + + LTA + +D L GA VLAD GI +D Sbjct: 251 CSEILHHVLDHLAPRGVYVDLRRTELTDLTAVLKED---RGWALRAGAAVLADGGILAVD 307 Query: 525 EFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNI 584 + E R A+ E M++ T+++ LNAR ++LAA NP G P P+ I Sbjct: 308 HLEGAPEPHRWALMEAMDKGTVTVD----GIALNARCAVLAAINP--GEQWPSDPPIARI 361 Query: 585 NLPAALLSRFDIL-FLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSKMREYIA 643 +L LS FD++ FL +D + +E+ E +Y + +R Y+ Sbjct: 362 DLDQDFLSHFDLIAFLGVDPRPGEPEEQDTEVPSY-----------------TLLRRYLL 404 Query: 644 YAKTKRPV--MSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAK 701 YA + P ++E + Y R++ + + T R L + RL++A A+ Sbjct: 405 YAIREHPAPELTEEARKRLEHWYETRREEVEERLGMGLPTLPVTRRQLESVERLAKAHAR 464 Query: 702 LRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDES 739 +RL+D V+ +DV+ A LV E+ Q + S Sbjct: 465 MRLSDDVEPEDVDIAAELVDWYLETAMQIPGGDEIRIS 502 >2R44-A nrPDB Length = 331 Score = 43.2 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 54/302 (17%), Positives = 124/302 (41%), Gaps = 30/302 (9%) Query: 455 NVCLMGDPGVAKSQLLKAICKIS----PRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEG 510 ++ L G PG+AK+ + + K R +T S L ++ + ++ Sbjct: 48 HILLEGVPGLAKTLSVNTLAKTMDLDFHRIQFTPDLLPS--DLIGTMIYNQHKGNFEVKK 105 Query: 511 GALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPL 570 G + + DE ++ ++A+ E M+++ ++I L+ +LA NP+ Sbjct: 106 GPVF---SNFILADEVNRSPAKVQSALLECMQEKQVTIGDT--TYPLDNPFLVLATQNPV 160 Query: 571 YGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNKQPDLDF 630 LP A + RF ++ + L ++ + ++ V+ ++ N Q Sbjct: 161 --EQEGTYP------LPEAQVDRF-MMKIHLTYLDKESELEVMRRVSNMN-FNYQVQKIV 210 Query: 631 TPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFG--QATPRT 688 + + ++R I +SE++ Y+++ R ++ ++++ S+ A+ R Sbjct: 211 SKNDVLEIRNEINKV-----TISESLEKYIIELVFATRFPAEYGLEAEASYILYGASTRA 265 Query: 689 LLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTKIFTII 748 + + R+++A+A D V +D++E + + E S I TI+ Sbjct: 266 AINLNRVAKAMAFFNNRDYVLPEDIKEVA--YDILNHRIILNYEAEAEGISTRQIIETIL 323 Query: 749 KK 750 +K Sbjct: 324 RK 325 >4QHS-A nrPDB Length = 267 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 49/225 (21%), Positives = 81/225 (36%), Gaps = 27/225 (12%) Query: 427 DVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPR--GVYTT 484 D K LL L V K D NV ++G G K + + I SPR G + Sbjct: 21 DTKSLKLLALADKVAKT---------DANVMILGPSGSGKEVMSRYIHNASPRKEGPFIA 71 Query: 485 GKGSSGVG--LTAAV---MKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHE 539 ++ L A + K T + G A G +DE +MD + + + Sbjct: 72 INCAAIPDNMLEATLFGYEKGAFTGAVQACPGKFEQAQGGTILLDEISEMDLNLQAKLLR 131 Query: 540 VMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFL 599 V++++ + + + L+ R +LA +N +Y + + L R ++ L Sbjct: 132 VLQEREVERLGSRKSIKLDVR--VLATSNRDLKQY------VQAGHFREDLYYRLNVFPL 183 Query: 600 MLDIPSRDDD--EKLAEHVTYVHMHN-KQPDLDFTPVEPSKMREY 641 D E LA H+ H P P +K+ Y Sbjct: 184 TWPALCERKDDIEPLANHLIERHCKKLGLPVPSIAPNAITKLLNY 228 >5EXX-A nrPDB Length = 343 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 48/339 (14%), Positives = 103/339 (30%), Gaps = 52/339 (15%) Query: 453 DINVCLMGDPGVAKSQLLKAICKISPR-----------GVYTTGKGSSGVGLTAAVMKDP 501 D +V ++G+ G K + + + S R + S G K Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 502 VTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNART 561 T + G LA+ G +DE M + + V++++T + G N T N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 562 SILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLA---EHVTY 618 I+AA + +++ L R + +F + P R+ E +A + Sbjct: 147 RIIAATHKN------LEKMIEDGTFREDLYYRLN-VFPIEMAPLRERVEDIALLLNELIS 199 Query: 619 VHMHNKQPDLDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYI----------RLR 668 H K+ + F + + P + + V + I L Sbjct: 200 RMEHEKRGSIRFNSAAIMSL------CRHDWPGNVRELANLVERLAIMHPYGVIGVGELP 253 Query: 669 QDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLY 728 + + D + L ++ L + M+ + ++ + Sbjct: 254 KKFRHVDDEDEQLASSLREELEERAAINAGLPGMDAPAMLPAEGLD---------LKDYL 304 Query: 729 QETNKSKEDESPTTKIFTIIKKMLQETGKNTLSYENIVK 767 + ++ + + + + T E + K Sbjct: 305 ANLEQGLIQQALDDAGGVVARAAERLRIRRTTLVEKMRK 343 >5EXS-A nrPDB Length = 260 Score = 40.5 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 46/125 (36%), Gaps = 17/125 (13%) Query: 453 DINVCLMGDPGVAKSQLLKAICKISPR-----------GVYTTGKGSSGVGLTAAVMKDP 501 D +V ++G+ G K + + + S R + S G K Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 502 VTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNART 561 T + G LA+ G +DE M + + V++++T + G N T N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 562 SILAA 566 I+AA Sbjct: 147 RIIAA 151 >4LZZ-A nrPDB Length = 268 Score = 39.7 bits (91), Expect = 0.006, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 66/204 (32%), Gaps = 28/204 (13%) Query: 456 VCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMI-LEGGALV 514 V + G+ GV K + + I K+S R K A++ +D E+ E GA Sbjct: 44 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 98 Query: 515 -----------LADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSI 563 LAD G +DE ++ + + V+E +N R I Sbjct: 99 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVR--I 156 Query: 564 LAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDE--KLAEHVTYVHM 621 LAA N + L R ++ + + ++ LA H Sbjct: 157 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 210 Query: 622 HNKQPDLDF-TPVEPSKMREYIAY 644 +++ T + Y Y Sbjct: 211 RKYAKEVEGFTKSAQELLLSYPWY 234 >1NY5-A nrPDB Length = 387 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 66/204 (32%), Gaps = 28/204 (13%) Query: 456 VCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMI-LEGGALV 514 V + G+ GV K + + I K+S R K A++ +D E+ E GA Sbjct: 163 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 217 Query: 515 -----------LADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSI 563 LAD G +DE ++ + + V+E +N R I Sbjct: 218 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVR--I 275 Query: 564 LAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDE--KLAEHVTYVHM 621 LAA N + L R ++ + + ++ LA H Sbjct: 276 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 329 Query: 622 HNKQPDLDF-TPVEPSKMREYIAY 644 +++ T + Y Y Sbjct: 330 RKYAKEVEGFTKSAQELLLSYPWY 353 >3DZD-A nrPDB Length = 368 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 29/119 (24%), Positives = 51/119 (42%), Gaps = 8/119 (6%) Query: 456 VCLMGDPGVAKSQLLKAICKISPR-GVYTTGKGSSGVGLTAAVM-----KDPVTDEMILE 509 V + G+ G K + + I + S R G + +S A K T + + Sbjct: 155 VLITGESGTGKEIVARLIHRYSGRKGAFVDLNCASIPQELAESELFGHEKGAFTGALTRK 214 Query: 510 GGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAAN 568 G L LAD G +DE ++D+ + + V+E T S ++ G N + +++A N Sbjct: 215 KGKLELADQGTLFLDEVGELDQRVQAKLLRVLE--TGSFTRLGGNQKIEVDIRVISATN 271 >3M6A-A nrPDB Length = 543 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 83/425 (19%), Positives = 155/425 (36%), Gaps = 62/425 (14%) Query: 347 DIVDVTGIFLPAPYTGFKALKA-GLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELI 405 + ++ G+ T K L + + E+ +R + + T + ++++ +L Sbjct: 15 EKIEEAGMPDHVKETALKELNRYEKIPSSSAESSVIRNYIDWLVALPWTDETDDKL-DLK 73 Query: 406 TSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVA 465 +G + + E +G VK+ +L L V K ++G I +CL G PGV Sbjct: 74 EAGRLLDE-------EHHGLEKVKERILEYL--AVQKLTK---SLKGPI-LCLAGPPGVG 120 Query: 466 KSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALV------LADNG 519 K+ L K+I K + G+ + L + + GA+ + G Sbjct: 121 KTSLAKSIAK-------SLGRKFVRISLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAG 173 Query: 520 ----ICCIDEFDKMDESDR----TAIHEVME-QQTISISKAGINTTLN-ARTSILAAANP 569 + +DE DKM R +A+ EV++ +Q S S I T + ++ +A AN Sbjct: 174 KLNPVFLLDEIDKMSSDFRGDPSSAMLEVLDPEQNSSFSDHYIEETFDLSKVLFIATANN 233 Query: 570 LYGRYNPRLSPLDNINLPAALLSRFDILFLMLD--IPSRDDDEKLAEHVTYVHMHNKQPD 627 L P ++ IN+ + + L ++ D +P + + L + + Sbjct: 234 LATIPGPLRDRMEIINIAG--YTEIEKLEIVKDHLLPKQIKEHGLKKSNLQLRDQAILDI 291 Query: 628 LDFTPVEP---SKMREYIAYAKTKRPVMSEAVNDYVV------QAYIRLRQDSKREMDSK 678 + + E S R+ A + + + Q +I R + +++ Sbjct: 292 IRYYTREAGVRSLERQLAAICRKAAKAIVAEERKRITVTEKNLQDFIGKRIFRYGQAETE 351 Query: 679 FSFGQAT--------PRTLLGIIRLSQALAKLRLA---DMVDIDDVEEALRLVRVSKESL 727 G T TL + LS KL L V + + A VR E L Sbjct: 352 DQVGVVTGLAYTTVGGDTLSIEVSLSPGKGKLILTGKLGDVMRESAQAAFSYVRSKTEEL 411 Query: 728 YQETN 732 E + Sbjct: 412 GIEPD 416 >4PEK-A nrPDB Length = 258 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 40/90 (44%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ L + D +D++ ALR+ ++ + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPLIIINDENDLDIALRIGARFIGIAARDWETGEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRG 773 + ++I + + K +S N ++ +R G Sbjct: 197 LISMIPSNVVKVAKEGISERNEIEELRKLG 226 >4L4U-A nrPDB Length = 447 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 39/204 (19%), Positives = 65/204 (31%), Gaps = 28/204 (13%) Query: 456 VCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMI-LEGGALV 514 V + G+ GV K + + I K S R K A++ +D E+ E GA Sbjct: 171 VLITGESGVGKEVVARLIHKSSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 225 Query: 515 -----------LADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSI 563 LAD G +DE ++ + + V+E +N R I Sbjct: 226 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVR--I 283 Query: 564 LAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDE--KLAEHVTYVHM 621 LAA N + L R ++ + + ++ LA H Sbjct: 284 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 337 Query: 622 HNKQPDLDF-TPVEPSKMREYIAY 644 +++ T + Y Y Sbjct: 338 RKYAKEVEGFTKSAQELLLSYPWY 361 >1OFI-A nrPDB Length = 310 Score = 36.3 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 54/126 (42%), Gaps = 16/126 (12%) Query: 414 LAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDI-------NVCLMGDPGVAK 466 + + I G D K+A+ + L + M+++ + N+ ++G GV K Sbjct: 9 IVSELDQHIIGQADAKRAVAIAL-----RNRWRRMQLQEPLRHEVTPKNILMIGPTGVGK 63 Query: 467 SQLLKAICKISPRGVYTTGKGSSGVGLTAAVMK-DPVTDEMILEGGALVLA--DNGICCI 523 +++ + + K++ + + + + + D + ++ G + A NGI I Sbjct: 64 TEIARRLAKLA-NAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAGGAIDAVEQNGIVFI 122 Query: 524 DEFDKM 529 DE DK+ Sbjct: 123 DEIDKI 128 >4BS1-B nrPDB Length = 173 Score = 35.9 bits (81), Expect = 0.077, Method: Composition-based stats. Identities = 31/125 (24%), Positives = 47/125 (37%), Gaps = 19/125 (15%) Query: 456 VCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMI-LEGGALV 514 V + G+ GV K + + I K+S R K A++ +D E+ E GA Sbjct: 27 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 81 Query: 515 -----------LADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSI 563 LAD G +DE ++ + + V+E +N R I Sbjct: 82 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESGKFYRLGGRKEIEVNVR--I 139 Query: 564 LAAAN 568 LAA N Sbjct: 140 LAATN 144 >4IJB-A nrPDB Length = 256 Score = 35.1 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 40/90 (44%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ L ++ D +D++ ALR+ Q+ + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPLIEINDENDLDIALRIGARFIGIWSQDNETLEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRG 773 + ++I + + +S N ++ +R G Sbjct: 197 LISMIPSNVVKVAGGGISERNEIEELRKLG 226 >1OJL-A nrPDB Length = 304 Score = 34.7 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 38/253 (15%), Positives = 83/253 (32%), Gaps = 38/253 (15%) Query: 453 DINVCLMGDPGVAKSQLLKAICKISPR-----------GVYTTGKGSSGVGLTAAVMKDP 501 D V + GD G K + +A+ S R + + S G K Sbjct: 25 DATVLIHGDSGTGKELVARALHACSARSDRPLVTLNCAALNESLLESELFGH----EKGA 80 Query: 502 VTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNART 561 T G V AD G +DE + + + ++++ + + G N T++ Sbjct: 81 FTGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQEREVQ--RVGSNQTISVDV 138 Query: 562 SILAAANPLYGRYNPRLSPLDNIN---LPAALLSRFDILFLMLDIPSRDDDE--KLAEHV 616 ++AA + + ++ L R +++ + + + ++ LA+H Sbjct: 139 RLIAATH---------RDLAEEVSAGRFRQDLYYRLNVVAIEMPSLRQRREDIPLLADHF 189 Query: 617 TYVHMHNKQPDLDF-TPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREM 675 + + TP + Y P + + + +A + L + E Sbjct: 190 LRRFAERNRKVVKGFTPQAMDLLIHY------DWPGNIRELENAIERAVVLLTGEYISER 243 Query: 676 DSKFSFGQATPRT 688 + + +T Sbjct: 244 ELPLAIAATPIKT 256 >5NZZ-A nrPDB Length = 504 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 38/99 (38%), Gaps = 8/99 (8%) Query: 311 QECKIQ-ELSQQVPVGHIPRSLNIHVNG--TLVRSLSPGDIVDVTGIFLPAPYTGFKALK 367 ++ +Q +L + VP +P + TL R +S G + V + Y Sbjct: 127 EKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTN 186 Query: 368 AGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELIT 406 LL ++ ++ V Q + T++ E+ + L Sbjct: 187 RALLCKSTVDGLQVTQ-----LNVDHTTENEDELFRLSQ 220 >2POM-A nrPDB Length = 372 Score = 34.7 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 38/99 (38%), Gaps = 8/99 (8%) Query: 311 QECKIQ-ELSQQVPVGHIPRSLNIHVNG--TLVRSLSPGDIVDVTGIFLPAPYTGFKALK 367 ++ +Q +L + VP +P + TL R +S G + V + Y Sbjct: 129 EKASLQSQLPEGVPQHQLPPQYQKILERLKTLEREISGGAMAVVAVLLNNKLYVANVGTN 188 Query: 368 AGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVMELIT 406 LL ++ ++ V Q + T++ E+ + L Sbjct: 189 RALLCKSTVDGLQVTQ-----LNVDHTTENEDELFRLSQ 222 >1IN6-A nrPDB Length = 334 Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 34/152 (22%), Positives = 60/152 (39%), Gaps = 30/152 (19%) Query: 404 LITSGDVYNRLAKSIAP----EIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDI--NVC 457 L VY+ + + P E G +VKK L L L + K+RG++ +V Sbjct: 5 LTPERTVYDSGVQFLRPKSLDEFIGQENVKKKLSLAL---------EAAKMRGEVLDHVL 55 Query: 458 LMGDPGVAKSQLLKAICKISPRGVY-TTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLA 516 L G PG+ ++ L I ++ T+G G AA++ L Sbjct: 56 LAGPPGLGRTTLAHIIASELQTNIHVTSGPVLVKQGDMAAILTS--------------LE 101 Query: 517 DNGICCIDEFDKMDESDRTAIHEVMEQQTISI 548 + IDE +++++ ++ +E I I Sbjct: 102 RGDVLFIDEIHRLNKAVEELLYSAIEDFQIDI 133 >1HQC-A nrPDB Length = 324 Score = 34.7 bits (78), Expect = 0.19, Method: Composition-based stats. Identities = 40/198 (20%), Positives = 65/198 (32%), Gaps = 37/198 (18%) Query: 401 VMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMG 460 + +L + G +K+ L + L ++ ++ L G Sbjct: 1 MEDLALRPKTLDEYI--------GQERLKQKLRVYLEAAKARKEPLE-------HLLLFG 45 Query: 461 DPGVAKSQLLKAICK-ISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNG 519 PG+ K+ L I + T+G G AA++ A L + Sbjct: 46 PPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAIL-------------ANSLEEGD 92 Query: 520 ICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLS 579 I IDE ++ ++ ME + I I ART L P + Sbjct: 93 ILFIDEIHRLSRQAEEHLYPAMEDFVMDIV---IGQGPAARTIRLEL--PRFTLIGATTR 147 Query: 580 PLDNINLPAALLSRFDIL 597 P + A LLSRF I+ Sbjct: 148 PGL---ITAPLLSRFGIV 162 >4PA8-A nrPDB Length = 258 Score = 34.3 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 16/100 (16%), Positives = 41/100 (41%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ L + D +D++ ALR+ + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPLILINDENDLDIALRIGARFIVIFSMNFETGEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCI 783 + ++I + + +S N ++ +R G +S+ + Sbjct: 197 LISMIPSNVVKVAHLDISERNEIEELRKLGVNAFLISSSL 236 >2QJ0-A nrPDB Length = 982 Score = 34.3 bits (77), Expect = 0.23, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 44/111 (39%), Gaps = 11/111 (9%) Query: 84 DILQYQNEKFLQGTQADDLVSAIQQNANHFTE-LFCRAIDNNMPLPTKEIDYKDDVLDVI 142 D+L+ ++ ++ + +SA+ ++ F LF RA+D L K + ++ + Sbjct: 822 DLLKALTTVYINLSEQSEFISAVAKDERSFNRNLFVRAVD---ILGRKTGLASPEFIEKL 878 Query: 143 LNQRRLRNERMLSDRTNEIRSENLMDTTMDPPSSMNDALREVVEDETELFP 193 LN E+ +D ++ D P D L + + + P Sbjct: 879 LNFANKAEEQRKADEEEDL-------EYGDVPDEFLDPLMYTIMKDPVILP 922 >2C3Z-A nrPDB Length = 222 Score = 34.0 bits (76), Expect = 0.26, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 42/90 (46%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ L ++ D +D++ ALR+ ++ + ++ K Sbjct: 111 LTERELESLLEYARSYGMEPLIEINDENDLDIALRIGARFIGINSRDLETLEINKENQRK 170 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRG 773 + ++I + + ++ +S N ++ +R G Sbjct: 171 LISMIPSNVVKVAESGISERNEIEELRKLG 200 >5W0T-A nrPDB Length = 304 Score = 33.6 bits (75), Expect = 0.34, Method: Composition-based stats. Identities = 59/279 (21%), Positives = 95/279 (34%), Gaps = 38/279 (13%) Query: 382 RQHKKKFASFSLTSD-VEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGV 440 + K+ A +T D E ++ I + D N + I D+ ++++ L+ + Sbjct: 7 KLVKRSPALAEVTLDAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLM--M 64 Query: 441 DKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKD 500 + + ++ V L G PG K+ L KA+ K S + + + SS + Sbjct: 65 PEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESG-ANFISIRMSSIMD-------- 115 Query: 501 PVTDEMILEGGALV-----LADN---GICCIDEFDKMDESDRTAIHEVMEQQTISISKAG 552 + E +V LA+ I IDE D + HEV Sbjct: 116 ----KWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFMTLW 171 Query: 553 INTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALL-------SRFDILFLMLDIPS 605 N R I+ A N R N LP L R+ IL ++L Sbjct: 172 DGLLNNGRVMIIGATN----RINDIDDAFLR-RLPKRFLVSLPGSDQRYKILSVLLKDTK 226 Query: 606 RDDDEKLAEHVTYVHMHNKQPDLDFTPVE--PSKMREYI 642 D+DE + + DL E +EYI Sbjct: 227 LDEDEFDLQLIADNTKGFSGSDLKELCREAALDAAKEYI 265 >3NYZ-A nrPDB Length = 261 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 39/90 (43%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ + D +D++ ALR+ E ++ + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPAIVINDENDLDIALRIGARFIEIASRDLETLEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRG 773 + ++I + + +S N ++ +R G Sbjct: 197 LISMIPSNVVKVAWQGISERNEIEELRKLG 226 >3HOJ-A nrPDB Length = 248 Score = 32.8 bits (73), Expect = 0.68, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 42/100 (42%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ L + D +D++ ALR+ + + + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPLIKINDENDLDIALRIGARFIGIVSADWETLEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCI 783 + ++I + + +S N ++ +R G + + + Sbjct: 197 LISMIPSNVVKVAAFGISERNEIEELRKLGVNAFSIHSSL 236 >1QVR-A nrPDB Length = 854 Score = 32.8 bits (73), Expect = 0.68, Method: Composition-based stats. Identities = 65/384 (16%), Positives = 131/384 (34%), Gaps = 72/384 (18%) Query: 394 TSDVEERVMELITSGDVYNRLAKS--IAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIR 451 T E L G RLA + P I + ++++ + +LL R Sbjct: 143 TEHAESTYNALEQYGIDLTRLAAEGKLDPVIGRDEEIRRVIQILL-------------RR 189 Query: 452 GDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGG 511 N L+G+PGV K+ + + ++ R V KG GL + L+ G Sbjct: 190 TKNNPVLIGEPGVGKTAI---VEGLAQRIV----KGDVPEGL-------KGKRIVSLQMG 235 Query: 512 ALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLY 571 +L+ G EF+ E + I EV++ Q + ++ +++ A Sbjct: 236 SLL---AGAKYRGEFE---ERLKAVIQEVVQSQ------GEVILFIDELHTVVGAGKAEG 283 Query: 572 GRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSR----DDDEKLAEHVTYVHMHNKQPD 627 +D N+ L+R ++ + + D L V++ + Sbjct: 284 A--------VDAGNMLKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYVDEPTVE 335 Query: 628 LDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPR 687 + + K + + + A + YI R+ + Sbjct: 336 ETISILRGLKEKYEVHHGVRISDSAIIAAAT-LSHRYITERRLPDK-------------- 380 Query: 688 TLLGIIRLSQALAKLRLADMVDIDDVEEALR-LVRVSKESLYQETNKSKEDESPTTKIFT 746 I + +A A+LR+A ++++ R +++ E + K + + I Sbjct: 381 ---AIDLIDEAAARLRMALESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEA 437 Query: 747 IIKKMLQETGKNTLSYENIVKTVR 770 I K+ +E K +E + +R Sbjct: 438 EIAKLTEEIAKLRAEWEREREILR 461 >4YPN-A nrPDB Length = 293 Score = 32.4 bits (72), Expect = 0.81, Method: Composition-based stats. Identities = 43/224 (19%), Positives = 82/224 (36%), Gaps = 24/224 (10%) Query: 330 SLNIHVNGTLVRSLSPGDIVDVTGIFLPAPYTGFKALKA-GLLTETYLEAQFVRQHKKKF 388 + L + ++ G+ K L + + EA R + Sbjct: 29 QKELGGEDGLSDLEALRKKIEEVGMPEAVKTKALKELDRLERMQQGSPEATVARTYLDWL 88 Query: 389 ASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGM 448 + + V+++ + V + + YG DVK+ +L L +++ G+ Sbjct: 89 TEVPWSKA-DPEVLDINHTRQVLDE-------DHYGLKDVKERILEYL---AVRQLTQGL 137 Query: 449 KIRGDINVC-LMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVT---- 503 +R + L+G PGV K+ L ++I + R + G GV A + T Sbjct: 138 DVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKFHRISLG--GVRDEAEIRGHRRTYIGA 195 Query: 504 -DEMILEGGALVLADNGICCIDEFDKMDESDR----TAIHEVME 542 ++ V N + +DE DKM R +A+ EV++ Sbjct: 196 MPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGDPASAMLEVLD 239 >4YPL-A nrPDB Length = 555 Score = 32.4 bits (72), Expect = 0.88, Method: Composition-based stats. Identities = 38/176 (21%), Positives = 71/176 (40%), Gaps = 23/176 (13%) Query: 377 EAQFVRQHKKKFASFSLTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLL 436 EA R + + + V+++ + V + + YG DVK+ +L L Sbjct: 44 EATVARTYLDWLTEVPWSKA-DPEVLDINHTRQVLDE-------DHYGLKDVKERILEYL 95 Query: 437 VGGVDKRVGDGMKIRGDINVC-LMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTA 495 +++ G+ +R + L+G PGV K+ L ++I + R + G GV A Sbjct: 96 ---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKFHRISLG--GVRDEA 150 Query: 496 AVMKDPVT-----DEMILEGGALVLADNGICCIDEFDKMDESDR----TAIHEVME 542 + T ++ V N + +D+ DKM R +A+ EV++ Sbjct: 151 EIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDQIDKMSSDWRGDPASAMLEVLD 206 >5AOU-A nrPDB Length = 258 Score = 32.0 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 11/65 (16%), Positives = 26/65 (40%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ ++ L + D +D++ ALR+ + ++ K Sbjct: 137 LTERELESLLEYARGYGMEPLILINDENDLDIALRIGARFITIYSMNFETGEINKENQRK 196 Query: 744 IFTII 748 + ++I Sbjct: 197 LISMI 201 >4I5O-A nrPDB Length = 363 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 36/168 (21%), Positives = 60/168 (35%), Gaps = 23/168 (13%) Query: 422 IYGNLDVKKALLLLLVGGVDKRVGDGMKIR---GDINVCLMGDPGVAKSQLLKAICKI-- 476 + G KK L + + + G N+ L+G G K+ L + + ++ Sbjct: 17 VIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLD 76 Query: 477 ----SPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKM-DE 531 T G G + + K + ++ A GI IDE DK+ + Sbjct: 77 VPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQK-----AQRGIVYIDEIDKISRK 131 Query: 532 SDRTAIHEVMEQQTISISKAGI-NTTLNARTSILAAANPLYGRYNPRL 578 SD +I T +S G+ L +AA P GR +P+ Sbjct: 132 SDNPSI-------TRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQ 172 >3UD6-A nrPDB Length = 258 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 14/96 (14%), Positives = 39/96 (40%) Query: 678 KFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKED 737 T R L ++ +++ + + D +D++ ALR+ ++ + + Sbjct: 131 PLIVKILTERELESLLEYARSYGMEPIIKINDENDLDIALRIGARFIGICSRDWETLEIN 190 Query: 738 ESPTTKIFTIIKKMLQETGKNTLSYENIVKTVRLRG 773 + K+ ++I + + +S N ++ +R G Sbjct: 191 KENQRKLISMIPSNVVKVASTGISERNEIEELRKLG 226 >5C3C-A nrPDB Length = 281 Score = 31.6 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 59/174 (33%), Gaps = 23/174 (13%) Query: 450 IRGDINVCLMGDPGVAKSQLLKAICKIS-----PRGVYTTGKGSSGVGLTAAVMKDPVTD 504 I + L G G KS + + ++ P + + L + D Sbjct: 44 YEARIPMMLKGPTGCGKS---RFVEHMAWKLNRPLITIACNEDMTASDLVGRYLLDKDGT 100 Query: 505 EMILEGGALVLAD--NGICCIDEFDKMDESDRTAIHEVMEQQTI-SISKAGINTTLNART 561 + G L +A IC +DE + + IH + + + + + K G + Sbjct: 101 RW--QDGPLTVAARIGAICYLDEIVEARQDTIVVIHPLTDHRRVLPLEKKGELVEAHPDF 158 Query: 562 SILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEH 615 I+ + NP G + +L + RF L D P D + ++ H Sbjct: 159 QIVISYNP--GYQSLMK------DLKQSTKQRFGA--LDFDYPKPDIEAEIVSH 202 >3UXA-A nrPDB Length = 252 Score = 31.3 bits (69), Expect = 1.9, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 43/100 (43%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ + D +D++ ALR+ ++ + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPAIVINDEEDLDIALRIGARIIIISSRDLETLEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRGFTMLQLSNCI 783 + ++I + + + +S N ++ +R G ++ + + Sbjct: 197 LISMIPSNVVKVAASGISERNEIEELRKLGVNAFEIGSSL 236 >1UM8-A nrPDB Length = 376 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 27/132 (20%), Positives = 50/132 (37%), Gaps = 12/132 (9%) Query: 455 NVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGS-SGVGLTAAVMKDPVTDEMILEGGAL 513 N+ L+G G K+ + + + K + + S + G +++ +T + + Sbjct: 74 NILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNV 133 Query: 514 VLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGIN---TTLNARTSILAAANPL 570 A GI IDE DK I + E ++I+ +G L L P Sbjct: 134 QKAQKGIVFIDEIDK--------ISRLSENRSITRDVSGEGVQQALLKIVEGSLVNIPPK 185 Query: 571 YGRYNPRLSPLD 582 GR +P + + Sbjct: 186 GGRKHPEGNFIQ 197 >3K1J-A nrPDB Length = 604 Score = 31.3 bits (69), Expect = 2.1, Method: Composition-based stats. Identities = 47/276 (17%), Positives = 94/276 (34%), Gaps = 72/276 (26%) Query: 479 RGVYTTGKGSSGVGLTAAVMKDPVTDE-------MILEGGALVLADNGICCIDEFDKMDE 531 + + G+ L V DP +E G + A G+ IDE + Sbjct: 156 KAPFIDATGAHAGALLGDVRHDPFQSGGLGTPAHERVEPGMIHRAHKGVLFIDEIATLSL 215 Query: 532 SDRTAIHEVMEQQTISIS-KAGINTTLNARTS-------ILAAANPLYGRYNPRLSPLDN 583 + ++ M+++ I+ ++ +++ RT ++AA N LD Sbjct: 216 KMQQSLLTAMQEKKFPITGQSEMSSGAMVRTEPVPCDFVLVAAGN------------LDT 263 Query: 584 IN-LPAALLSRFD----ILFLMLDIPSR-DDDEKLAEHVTYVHMHNKQPDLDFTPVEPSK 637 ++ + AL SR +++ +P ++ KL + V + + Sbjct: 264 VDKMHPALRSRIRGYGYEVYMRTTMPDTIENRRKLVQFVAQEVKRDGKI----------- 312 Query: 638 MREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQ 697 P ++ + +V R+ KR + R L GI+R + Sbjct: 313 ------------PHFTKEAVEEIV------REAQKRAGRKGHLTLRL--RDLGGIVRAAG 352 Query: 698 ALAKLRLADMVDIDDVEEALR--------LVRVSKE 725 +A + V+ +DV EA++ L E Sbjct: 353 DIAVKKGKKYVEREDVIEAVKMAKPLEKQLADWYIE 388 Score = 30.1 bits (66), Expect = 4.1, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 17/24 (70%) Query: 455 NVCLMGDPGVAKSQLLKAICKISP 478 +V L+G+PG KS L +A+ ++ P Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >5GQY-A nrPDB Length = 793 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 30/54 (55%), Gaps = 2/54 (3%) Query: 48 DAENIEQHLLEKGPKYMAMLQKVANRELNSVIIDLDDILQYQNEKFLQGTQADD 101 + +N E H+ EK Y + N S+++D+D+I Q+ +E++L+ + D Sbjct: 214 EIKNSEGHIYEKSDPYGFYREVRPNTA--SIVVDIDNIYQWHDEEWLEKRRNSD 265 >2ISS-A nrPDB Length = 313 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 24/58 (41%), Gaps = 2/58 (3%) Query: 690 LGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTKIFTI 747 + R+++ A +R +V EA++ +R E + Q T EDE I Sbjct: 155 EALRRIAEGAAMIRTKGEAGTGNVVEAVKHMRRVMEQIKQVTKM--EDEELVAYGKEI 210 >3N37-A nrPDB Length = 319 Score = 30.9 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 20/60 (33%), Positives = 31/60 (51%), Gaps = 8/60 (13%) Query: 60 GPKYMAMLQKVA---NRELNSVIIDL-----DDILQYQNEKFLQGTQADDLVSAIQQNAN 111 G KY ++K++ EL S DL D+ LQY +E + + ADD+ + + NAN Sbjct: 200 GYKYQKNMEKISLGQREELKSFAFDLLLELYDNELQYTDELYAETPWADDVKAFLCYNAN 259 >4ZPX-A nrPDB Length = 413 Score = 30.5 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 10/24 (41%), Positives = 17/24 (70%) Query: 455 NVCLMGDPGVAKSQLLKAICKISP 478 +V L+G+PG KS L +A+ ++ P Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >1RWG-A nrPDB Length = 757 Score = 30.5 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 36/148 (24%), Positives = 60/148 (40%), Gaps = 18/148 (12%) Query: 450 IRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILE 509 + GD+ VCL D A ++ I + R ++ +GS+ LT A T + Sbjct: 506 VSGDVTVCLGADISTASGAKVETI--VDHRNLH---QGSNT--LTTAAGTIAGTAGTV-- 556 Query: 510 GGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGIN--TTLNARTSILAAA 567 VL D ++ F D + +H + E ++ S S IN T+ R Sbjct: 557 ---EVLGDGRWVHLEGFGGYAMLDDSPLHVLRETRSGSWSGVNINGSATVQQRNFATLYV 613 Query: 568 N----PLYGRYNPRLSPLDNINLPAALL 591 N P+ G Y ++P +++L LL Sbjct: 614 NHGVGPVAGSYAYMVAPGASVDLTRKLL 641 >3TC6-A nrPDB Length = 258 Score = 30.5 bits (67), Expect = 3.6, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 39/90 (43%) Query: 684 ATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDESPTTK 743 T R L ++ +++ L + D +D++ ALR+ ++ + ++ K Sbjct: 137 LTERELESLLEYARSYGMEPLIVINDENDLDIALRIGARFIGIESRDWETLEINKENQRK 196 Query: 744 IFTIIKKMLQETGKNTLSYENIVKTVRLRG 773 + ++I + + +S N ++ +R G Sbjct: 197 LISMIPSNVVKVAIAGISERNEIEELRKLG 226 >4V7Q-BX nrPDB Length = 776 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 23/75 (30%), Gaps = 3/75 (4%) Query: 155 SDRTNEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQN---C 211 DR+ +I L D + V + E+F R+F Y Sbjct: 645 IDRSTQISPNTLPDIVTEASEKFIPNRAYRVINNDEVFEAGTDGRFFAYRVETFDEIPFD 704 Query: 212 ARRYRKKAISSKPLS 226 +++ S +S Sbjct: 705 VQKFADLVTDSPVIS 719 >2D2N-C nrPDB Length = 147 Score = 30.1 bits (66), Expect = 4.5, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 26/73 (35%), Gaps = 9/73 (12%) Query: 417 SIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRG---------DINVCLMGDPGVAKS 467 ++A ++ +L + A L GV D R D+ + ++ DP V Sbjct: 30 ALAQAVFASLFSRDAAAQGLFSGVSADNPDSADFRAHCVRVVNGLDVAINMLNDPAVLNE 89 Query: 468 QLLKAICKISPRG 480 QL + R Sbjct: 90 QLAHLSAQHQARA 102 >4HSE-A nrPDB Length = 397 Score = 30.1 bits (66), Expect = 4.6, Method: Composition-based stats. Identities = 65/384 (16%), Positives = 131/384 (34%), Gaps = 72/384 (18%) Query: 394 TSDVEERVMELITSGDVYNRLAKS--IAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIR 451 T E L G RLA + P I + ++++ + +LL R Sbjct: 6 TEHAESTYNALEQYGIDLTRLAAEGKLDPVIGRDEEIRRVIQILL-------------RR 52 Query: 452 GDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGG 511 N L+G+PGV K+ + + ++ R V KG GL + L+ G Sbjct: 53 TKNNPVLIGEPGVGKTAI---VEGLAQRIV----KGDVPEGL-------KGKRIVSLQMG 98 Query: 512 ALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSILAAANPLY 571 +L+ G EF+ E + I EV++ Q + ++ +++ A Sbjct: 99 SLL---AGAKYRGEFE---ERLKAVIQEVVQSQ------GEVILFIDELHTVVGAGKAEG 146 Query: 572 GRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSR----DDDEKLAEHVTYVHMHNKQPD 627 +D N+ L+R ++ + + D L V++ + Sbjct: 147 A--------VDAGNMLKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYVDEPTVE 198 Query: 628 LDFTPVEPSKMREYIAYAKTKRPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPR 687 + + K + + + A + YI R+ + Sbjct: 199 ETISILRGLKEKYEVHHGVRISDSAIIAAAT-LSHRYITERRLPDK-------------- 243 Query: 688 TLLGIIRLSQALAKLRLADMVDIDDVEEALR-LVRVSKESLYQETNKSKEDESPTTKIFT 746 I + +A A+LR+A ++++ R +++ E + K + + I Sbjct: 244 ---AIDLIDEAAARLRMALESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEA 300 Query: 747 IIKKMLQETGKNTLSYENIVKTVR 770 I K+ +E K +E + +R Sbjct: 301 EIAKLTEEIAKLRAEWEREREILR 324 >2Q58-A nrPDB Length = 368 Score = 29.7 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 28/61 (45%) Query: 398 EERVMELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVC 457 E + I D + + ++ ++ N +++K ++ + +D V G IRG I V Sbjct: 22 EYDYTDFINYYDKFKVIVYNVLKKLPLNDEIRKPVIEYYLNCIDYNVKKGKHIRGKILVL 81 Query: 458 L 458 + Sbjct: 82 I 82 >3U5Z-B nrPDB Length = 324 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 40/122 (32%), Gaps = 15/122 (12%) Query: 456 VCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVL 515 + PG K+ + KA+C V +G ++ P+T+ A Sbjct: 51 ILHSPSPGTGKTTVAKALCH----DVNADMMFVNGSDCKIDFVRGPLTN---FASAASFD 103 Query: 516 ADNGICCIDEFDKM----DESDRTAIHEVMEQQTISISKA----GINTTLNARTSILAAA 567 + IDEFD+ + + E I A GI L +R ++ Sbjct: 104 GRQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQSRCRVITFG 163 Query: 568 NP 569 P Sbjct: 164 QP 165 >4F8X-A nrPDB Length = 335 Score = 29.7 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 23/53 (43%), Gaps = 3/53 (5%) Query: 461 DPGVAKSQLLKAICKISPRGVYTTGKGSSG---VGLTAAVMKDPVTDEMILEG 510 +PG + +L+ + + RG+ G G VG T ++ T + ++ Sbjct: 185 NPGTKSTAVLQLVSNLRKRGIRIDGVGLESHFIVGETPSLADQLATKQAYIKA 237 >3CRV-A nrPDB Length = 551 Score = 29.7 bits (65), Expect = 5.3, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 34/81 (41%), Gaps = 7/81 (8%) Query: 601 LDIPSRDDDEKLAEHVTYVHMHNKQPDLDFTPVEPSK--MREYIA----YAKTKR-PVMS 653 LD + ++ L+E + + + + + +RE + Y K + P +S Sbjct: 185 LDKVNELEERSLSEITIQMAIKQSKSEESRRILSKLLNQLREVVLPDEKYIKVENVPKLS 244 Query: 654 EAVNDYVVQAYIRLRQDSKRE 674 + + + Y +R+DS ++ Sbjct: 245 KEELEILADDYEDIRKDSLKQ 265 >4LJ8-A nrPDB Length = 339 Score = 28.9 bits (63), Expect = 8.4, Method: Composition-based stats. Identities = 12/70 (17%), Positives = 27/70 (38%), Gaps = 3/70 (4%) Query: 649 RPVMSEAVNDYVVQAYIRLRQDSKREMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMV 708 + + V + Q + R + +D F T + I+ + + + RLA+ Sbjct: 210 YERIRDEVFKVLQQHF---RPEFLNRLDEIVVFRPLTKEQIRQIVEIQLSYLRARLAEKR 266 Query: 709 DIDDVEEALR 718 ++ EA + Sbjct: 267 ISLELTEAAK 276 >2Z4R-A nrPDB Length = 440 Score = 28.9 bits (63), Expect = 8.8, Method: Composition-based stats. Identities = 7/54 (12%), Positives = 18/54 (33%), Gaps = 1/54 (1%) Query: 576 PRLSPLDNINLPAALLSRFDILFLML-DIPSRDDDEKLAEHVTYVHMHNKQPDL 628 P L+SRF + + + P + + +A + + ++ Sbjct: 234 SDREPQKLSEFQDRLVSRFQMGLVAKLEPPDEETRKSIARKMLEIEHGELPEEV 287 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.128 0.325 Lambda K H 0.267 0.0395 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,613,065 Number of Sequences: 36641 Number of extensions: 1105513 Number of successful extensions: 3824 Number of sequences better than 10.0: 64 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 55 Number of HSP's that attempted gapping in prelim test: 3664 Number of HSP's gapped (non-prelim): 111 length of query: 845 length of database: 10,336,785 effective HSP length: 105 effective length of query: 740 effective length of database: 6,489,480 effective search space: 4802215200 effective search space used: 4802215200 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (28.9 bits)