BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P38117
         (255 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

2A1U-B nrPDB                                                          504   e-143
1EFP-B nrPDB                                                          282   1e-76
6FAH-B nrPDB                                                          110   6e-25
3CLR-C nrPDB                                                          107   7e-24
5OL2-B nrPDB                                                          100   5e-22
4KPU-B nrPDB                                                           95   2e-20
5OW0-B nrPDB                                                           56   2e-08
6AGB-I nrPDB                                                           29   1.6  
2KVK-A nrPDB                                                           28   5.5  
6F3O-A nrPDB                                                           27   10.0 

>2A1U-B nrPDB
          Length = 255

 Score =  504 bits (1298), Expect = e-143,   Method: Compositional matrix adjust.
 Identities = 254/255 (99%), Positives = 254/255 (99%)

Query: 1   MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKE 60
           MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKE
Sbjct: 1   MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKE 60

Query: 61  VIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLV 120
           VIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLV
Sbjct: 61  VIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLV 120

Query: 121 LLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAV 180
           LLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVER IDGGLETLRLKLPAV
Sbjct: 121 LLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVERAIDGGLETLRLKLPAV 180

Query: 181 VTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVE 240
           VTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVE
Sbjct: 181 VTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVE 240

Query: 241 TTEDLVAKLKEIGRI 255
           TTEDLVAKLKEIGRI
Sbjct: 241 TTEDLVAKLKEIGRI 255


>1EFP-B nrPDB
          Length = 252

 Score =  282 bits (721), Expect = 1e-76,   Method: Compositional matrix adjust.
 Identities = 148/252 (58%), Positives = 182/252 (72%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           ++VLV VKR+IDY VK RVK D +GV    VK SMNPF EIAVEEA+RLKEK   +E+IA
Sbjct: 1   MKVLVPVKRLIDYNVKARVKSDGSGVDLANVKMSMNPFDEIAVEEAIRLKEKGQAEEIIA 60

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLG 123
           VS G  Q  ET+RTALAMGADR I V       + + PL VA++LA +A  E  +L++ G
Sbjct: 61  VSIGVKQAAETLRTALAMGADRAILVVAADDVQQDIEPLAVAKILAAVARAEGTELIIAG 120

Query: 124 KQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTA 183
           KQAID+D N TGQM A  L W Q TFAS+V +EG K KV RE+DGGL+T+ + LPAVVTA
Sbjct: 121 KQAIDNDMNATGQMLAAILGWAQATFASKVEIEGAKAKVTREVDGGLQTIAVSLPAVVTA 180

Query: 184 DLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTE 243
           DLRLNEPRYA+LPNIMKAKKK ++     D GVD+  +L V+SV +P  R AG+KV + +
Sbjct: 181 DLRLNEPRYASLPNIMKAKKKPLDEKTAADYGVDVAPRLEVVSVREPEGRKAGIKVGSVD 240

Query: 244 DLVAKLKEIGRI 255
           +LV KLKE G I
Sbjct: 241 ELVGKLKEAGVI 252


>6FAH-B nrPDB
          Length = 262

 Score =  110 bits (275), Expect = 6e-25,   Method: Compositional matrix adjust.
 Identities = 82/260 (31%), Positives = 130/260 (50%), Gaps = 14/260 (5%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           +R+LV  K+V D   ++++ P    ++ +GV   +NP    A+E A+ +K++    EVI 
Sbjct: 1   MRILVCAKQVPDTN-EVKIDPKTGTMIREGVPSILNPDDANALEAALVIKDENPGTEVIV 59

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLG 123
           ++ GP Q  E +R  LAMGAD   ++    A          A + A + + +KVDLVL G
Sbjct: 60  MTMGPPQASEMLRECLAMGADEA-YLLSDRAFGGADTWATSATLAAGIKKVKKVDLVLAG 118

Query: 124 KQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTA 183
           +QAID D  Q G   A  L  P  T+   + +E  K  V R+++ G E + ++LP ++T 
Sbjct: 119 RQAIDGDTAQVGSQIAQRLKMPVVTYVEDIKIEDKKAIVHRQMEDGYEVIEVQLPCLLTC 178

Query: 184 DLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVD------LTSKLSVISVEDPPQRTAGV 237
              LN+PRY ++  IM A ++ I +    D+G+         S   V     PP +  G 
Sbjct: 179 VKELNDPRYMSVGGIMDAYEQPITIWNHEDIGLSPEACGLNASPTQVFRSFSPPAKGGGE 238

Query: 238 KV------ETTEDLVAKLKE 251
            +      E    LV+KLKE
Sbjct: 239 MITGTTVNEVAGSLVSKLKE 258


>3CLR-C nrPDB
          Length = 264

 Score =  107 bits (266), Expect = 7e-24,   Method: Compositional matrix adjust.
 Identities = 70/217 (32%), Positives = 117/217 (53%), Gaps = 6/217 (2%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           +++LVAVK+         ++ D   V  D + + +N + + ++EEA+++KE       + 
Sbjct: 1   MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVV 60

Query: 64  VSC-GPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLL 122
           V   GP +  E++R  LA GADR + V    AE      + V R+L ++ +KE  D+V  
Sbjct: 61  VVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGS--DAIVVGRILTEVIKKEAPDMVFA 118

Query: 123 GKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLE-GD-KLKVEREIDGG-LETLRLKLPA 179
           G Q+ D     TG   A +L+WP     + +  + GD K  + RE++GG L+ + +  PA
Sbjct: 119 GVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPA 178

Query: 180 VVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGV 216
           V+T  L +N+PRYA+L  I +A  K IE +   D+G+
Sbjct: 179 VLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGL 215


>5OL2-B nrPDB
          Length = 260

 Score =  100 bits (249), Expect = 5e-22,   Method: Compositional matrix adjust.
 Identities = 69/223 (30%), Positives = 120/223 (53%), Gaps = 16/223 (7%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           + ++V +K+V D   ++++ P+   ++ DGV   +NP  +  +EEA++LKE+ +   V  
Sbjct: 1   MNIVVCIKQVPD-TTEVKLDPNTGTLIRDGVPSIINPDDKAGLEEAIKLKEE-MGAHVTV 58

Query: 64  VSCGPAQCQETIRTALAMGADRGIHV-EVPPAEAERLGPLQVARVLAKLAEKEKVDLVLL 122
           ++ GP Q    ++ ALAMGADRGI + +   A A+       +  LA   +    D+++ 
Sbjct: 59  ITMGPPQADMALKEALAMGADRGILLTDRAFAGADTWA---TSSALAGALKNIDFDIIIA 115

Query: 123 GKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVT 182
           G+QAID D  Q G   A  L+ P  T+A ++  EG+ + V+R+ +     L++K+P ++T
Sbjct: 116 GRQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFEDCCHDLKVKMPCLIT 175

Query: 183 ADLRLNEPRYATLPNIMKAKK---------KKIEVIKPGDLGV 216
               +N PRY  +  I  A +         K IEV  P +LG+
Sbjct: 176 TLKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEV-DPSNLGL 217


>4KPU-B nrPDB
          Length = 263

 Score = 95.1 bits (235), Expect = 2e-20,   Method: Compositional matrix adjust.
 Identities = 72/219 (32%), Positives = 114/219 (52%), Gaps = 12/219 (5%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           + ++V VK+V D A ++++ P    +V DGV + MNP+ + A+E A++LK++ L   V  
Sbjct: 1   MNIVVCVKQVPDTA-EMKIDPVTNNLVRDGVTNIMNPYDQYALETALQLKDE-LGAHVTV 58

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKV----DL 119
           ++ GP   +  +R  LA+GAD     E         G        A +A   K     DL
Sbjct: 59  ITMGPPHAESVLRDCLAVGAD-----EAKLVSDRAFGGADTLATSAAMANTIKHFGVPDL 113

Query: 120 VLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPA 179
           +L G+QAID D  Q G   A  L  PQ T A +V ++ D + V+R+ +    T  +K+P 
Sbjct: 114 ILCGRQAIDGDTAQVGPEIAEHLGLPQVTAALKVQVKDDTVVVDRDNEQMSMTFTMKMPC 173

Query: 180 VVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDL 218
           VVT  +R  + R+A++   MKA+K +I V     L + L
Sbjct: 174 VVTV-MRSKDLRFASIRGKMKARKAEIPVYTAAALEIPL 211


>5OW0-B nrPDB
          Length = 251

 Score = 55.8 bits (133), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 60/186 (32%), Positives = 88/186 (47%), Gaps = 8/186 (4%)

Query: 41  FCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLG 100
           + E AVE  V+LKEK L  ++  VS G     + +R ALAMGAD+ + VE      +   
Sbjct: 38  YDENAVELGVQLKEK-LGADLTVVSYGRNDDVQFLRKALAMGADKVVLVE-----GDSDD 91

Query: 101 PLQVARVLAKLAEKE-KVDLVLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDK 159
           P  +A  L    +++  VDL+L G+Q+ D D      + AG LD P    A  V      
Sbjct: 92  PYVIAANLKDAIDRQGTVDLILAGRQSSDMDRGVVPGVLAGMLDLPFVPQACSVESVDGG 151

Query: 160 LKVEREIDGGLETLRLKLPAVVT-ADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDL 218
            K+ +  + G   L+L    V++   +  N PR   +  I  AKKK +E +     G   
Sbjct: 152 WKISQITETGKRLLKLSGKGVLSITSVPENVPRIPAVKAIFAAKKKPVEKLPEIGTGKMA 211

Query: 219 TSKLSV 224
            S+LSV
Sbjct: 212 VSELSV 217


>6AGB-I nrPDB
          Length = 293

 Score = 29.3 bits (64), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 26/110 (23%), Positives = 52/110 (47%), Gaps = 12/110 (10%)

Query: 144 WPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNE----PRYATLPNIM 199
           WPQ ++A +VT +     ++      L TL +     +  +  +N     P    L N +
Sbjct: 9   WPQNSYADKVTSQAVNNLIKT-----LSTLHMLGYTHIAINFTVNHSEKFPNDVKLLNPI 63

Query: 200 KAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTEDLVAKL 249
             K++  E++     G+ L S++++I ++DP +  +  K+    D+VA L
Sbjct: 64  DIKRRFGELMDR--TGLKLYSRITLI-IDDPSKGQSLSKISQAFDIVAAL 110


>2KVK-A nrPDB
          Length = 144

 Score = 27.7 bits (60), Expect = 5.5,   Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 24/47 (51%), Gaps = 2/47 (4%)

Query: 184 DLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDP 230
           DLR+ + RY  +   + A  KKIEV + G+  V+ T      S E P
Sbjct: 18  DLRMKKSRYVMM--CIGADGKKIEVTEVGERSVNYTDLKEKFSTEKP 62


>6F3O-A nrPDB
          Length = 472

 Score = 26.6 bits (57), Expect = 10.0,   Method: Compositional matrix adjust.
 Identities = 13/29 (44%), Positives = 18/29 (62%)

Query: 181 VTADLRLNEPRYATLPNIMKAKKKKIEVI 209
           V A + L E +YA LP   KAK+  +EV+
Sbjct: 398 VLAQIHLFEQKYADLPAAEKAKRLSVEVL 426


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

2A1U-B nrPDB                                                          336   7e-93
6FAH-B nrPDB                                                          301   2e-82
1EFP-B nrPDB                                                          280   4e-76
5OL2-B nrPDB                                                          261   2e-70
4KPU-B nrPDB                                                          236   5e-63
3CLR-C nrPDB                                                          224   4e-59
5OW0-B nrPDB                                                          190   5e-49

Sequences not found previously or not previously below threshold:

4XYJ-A nrPDB                                                           36   0.018
3JUK-A nrPDB                                                           31   0.52 
6BX7-A nrPDB                                                           31   0.54 
3C2O-A nrPDB                                                           30   0.86 
1RNL-A nrPDB                                                           28   4.2  
4LRT-B nrPDB                                                           28   5.3  


CONVERGED!
>2A1U-B nrPDB
          Length = 255

 Score =  336 bits (861), Expect = 7e-93,   Method: Composition-based stats.
 Identities = 254/255 (99%), Positives = 254/255 (99%)

Query: 1   MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKE 60
           MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKE
Sbjct: 1   MAELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKE 60

Query: 61  VIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLV 120
           VIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLV
Sbjct: 61  VIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLV 120

Query: 121 LLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAV 180
           LLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVER IDGGLETLRLKLPAV
Sbjct: 121 LLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVERAIDGGLETLRLKLPAV 180

Query: 181 VTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVE 240
           VTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVE
Sbjct: 181 VTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVE 240

Query: 241 TTEDLVAKLKEIGRI 255
           TTEDLVAKLKEIGRI
Sbjct: 241 TTEDLVAKLKEIGRI 255


>6FAH-B nrPDB
          Length = 262

 Score =  301 bits (770), Expect = 2e-82,   Method: Composition-based stats.
 Identities = 83/264 (31%), Positives = 131/264 (49%), Gaps = 14/264 (5%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           +R+LV  K+V D   ++++ P    ++ +GV   +NP    A+E A+ +K++    EVI 
Sbjct: 1   MRILVCAKQVPDTN-EVKIDPKTGTMIREGVPSILNPDDANALEAALVIKDENPGTEVIV 59

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLG 123
           ++ GP Q  E +R  LAMGAD   ++    A          A + A + + +KVDLVL G
Sbjct: 60  MTMGPPQASEMLRECLAMGADEA-YLLSDRAFGGADTWATSATLAAGIKKVKKVDLVLAG 118

Query: 124 KQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTA 183
           +QAID D  Q G   A  L  P  T+   + +E  K  V R+++ G E + ++LP ++T 
Sbjct: 119 RQAIDGDTAQVGSQIAQRLKMPVVTYVEDIKIEDKKAIVHRQMEDGYEVIEVQLPCLLTC 178

Query: 184 DLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVD------LTSKLSVISVEDPPQRTAGV 237
              LN+PRY ++  IM A ++ I +    D+G+         S   V     PP +  G 
Sbjct: 179 VKELNDPRYMSVGGIMDAYEQPITIWNHEDIGLSPEACGLNASPTQVFRSFSPPAKGGGE 238

Query: 238 KV------ETTEDLVAKLKEIGRI 255
            +      E    LV+KLKE   I
Sbjct: 239 MITGTTVNEVAGSLVSKLKEKHII 262


>1EFP-B nrPDB
          Length = 252

 Score =  280 bits (716), Expect = 4e-76,   Method: Composition-based stats.
 Identities = 148/252 (58%), Positives = 182/252 (72%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           ++VLV VKR+IDY VK RVK D +GV    VK SMNPF EIAVEEA+RLKEK   +E+IA
Sbjct: 1   MKVLVPVKRLIDYNVKARVKSDGSGVDLANVKMSMNPFDEIAVEEAIRLKEKGQAEEIIA 60

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLG 123
           VS G  Q  ET+RTALAMGADR I V       + + PL VA++LA +A  E  +L++ G
Sbjct: 61  VSIGVKQAAETLRTALAMGADRAILVVAADDVQQDIEPLAVAKILAAVARAEGTELIIAG 120

Query: 124 KQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTA 183
           KQAID+D N TGQM A  L W Q TFAS+V +EG K KV RE+DGGL+T+ + LPAVVTA
Sbjct: 121 KQAIDNDMNATGQMLAAILGWAQATFASKVEIEGAKAKVTREVDGGLQTIAVSLPAVVTA 180

Query: 184 DLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSVISVEDPPQRTAGVKVETTE 243
           DLRLNEPRYA+LPNIMKAKKK ++     D GVD+  +L V+SV +P  R AG+KV + +
Sbjct: 181 DLRLNEPRYASLPNIMKAKKKPLDEKTAADYGVDVAPRLEVVSVREPEGRKAGIKVGSVD 240

Query: 244 DLVAKLKEIGRI 255
           +LV KLKE G I
Sbjct: 241 ELVGKLKEAGVI 252


>5OL2-B nrPDB
          Length = 260

 Score =  261 bits (666), Expect = 2e-70,   Method: Composition-based stats.
 Identities = 75/260 (28%), Positives = 129/260 (49%), Gaps = 16/260 (6%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           + ++V +K+V D   ++++ P+   ++ DGV   +NP  +  +EEA++LKE+ +   V  
Sbjct: 1   MNIVVCIKQVPDT-TEVKLDPNTGTLIRDGVPSIINPDDKAGLEEAIKLKEE-MGAHVTV 58

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLG 123
           ++ GP Q    ++ ALAMGADRGI +    A A        +  LA   +    D+++ G
Sbjct: 59  ITMGPPQADMALKEALAMGADRGILL-TDRAFAGADTWA-TSSALAGALKNIDFDIIIAG 116

Query: 124 KQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTA 183
           +QAID D  Q G   A  L+ P  T+A ++  EG+ + V+R+ +     L++K+P ++T 
Sbjct: 117 RQAIDGDTAQVGPQIAEHLNLPSITYAEEIKTEGEYVLVKRQFEDCCHDLKVKMPCLITT 176

Query: 184 DLRLNEPRYATLPNIMKAKKKK-IEVIKPGDLGVDLT------SKLSVISVEDPPQRTAG 236
              +N PRY  +  I  A +   +E     D+ VD +      S  SV        + AG
Sbjct: 177 LKDMNTPRYMKVGRIYDAFENDVVETWTVKDIEVDPSNLGLKGSPTSVFKSFTKSVKPAG 236

Query: 237 VKVE-----TTEDLVAKLKE 251
                    +   ++ KLKE
Sbjct: 237 TIYNEDAKTSAGIIIDKLKE 256


>4KPU-B nrPDB
          Length = 263

 Score =  236 bits (603), Expect = 5e-63,   Method: Composition-based stats.
 Identities = 75/237 (31%), Positives = 118/237 (49%), Gaps = 18/237 (7%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           + ++V VK+V D A ++++ P    +V DGV + MNP+ + A+E A++LK++ L   V  
Sbjct: 1   MNIVVCVKQVPDTA-EMKIDPVTNNLVRDGVTNIMNPYDQYALETALQLKDE-LGAHVTV 58

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKV----DL 119
           ++ GP   +  +R  LA+GAD    V          G        A +A   K     DL
Sbjct: 59  ITMGPPHAESVLRDCLAVGADEAKLV-----SDRAFGGADTLATSAAMANTIKHFGVPDL 113

Query: 120 VLLGKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPA 179
           +L G+QAID D  Q G   A  L  PQ T A +V ++ D + V+R+ +    T  +K+P 
Sbjct: 114 ILCGRQAIDGDTAQVGPEIAEHLGLPQVTAALKVQVKDDTVVVDRDNEQMSMTFTMKMPC 173

Query: 180 VVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDL------TSKLSVISVEDP 230
           VVT  +R  + R+A++   MKA+K +I V     L + L       S   V+    P
Sbjct: 174 VVTV-MRSKDLRFASIRGKMKARKAEIPVYTAAALEIPLDIIGKAGSPTQVMKSFTP 229


>3CLR-C nrPDB
          Length = 264

 Score =  224 bits (570), Expect = 4e-59,   Method: Composition-based stats.
 Identities = 78/259 (30%), Positives = 134/259 (51%), Gaps = 12/259 (4%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVK-EVI 62
           +++LVAVK+         ++ D   V  D + + +N + + ++EEA+++KE      EV+
Sbjct: 1   MKILVAVKQTAALEEDFEIREDGMDVDEDFMMYDLNEWDDFSLEEAMKIKESSDTDVEVV 60

Query: 63  AVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLL 122
            VS GP +  E++R  LA GADR + V    AE      + V R+L ++ +KE  D+V  
Sbjct: 61  VVSVGPDRVDESLRKCLAKGADRAVRVWDDAAEGS--DAIVVGRILTEVIKKEAPDMVFA 118

Query: 123 GKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLE--GDKLKVEREIDGG-LETLRLKLPA 179
           G Q+ D     TG   A +L+WP     + +  +   +K  + RE++GG L+ + +  PA
Sbjct: 119 GVQSSDQAYASTGISVASYLNWPHAAVVADLQYKPGDNKAVIRRELEGGMLQEVEINCPA 178

Query: 180 VVTADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVD-----LTSKLSVISVEDPPQRT 234
           V+T  L +N+PRYA+L  I +A  K IE +   D+G+          +S +     P++ 
Sbjct: 179 VLTIQLGINKPRYASLRGIKQAATKPIEEVSLADIGLSANDVGAAQSMSRVRRMYIPEKG 238

Query: 235 AGVKVE-TTEDLVAKLKEI 252
               +E T  +  AK+ +I
Sbjct: 239 RATMIEGTISEQAAKIIQI 257


>5OW0-B nrPDB
          Length = 251

 Score =  190 bits (482), Expect = 5e-49,   Method: Composition-based stats.
 Identities = 66/223 (29%), Positives = 99/223 (44%), Gaps = 8/223 (3%)

Query: 4   LRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIA 63
           ++++V  K V DY V                   +  + E AVE  V+LKEK L  ++  
Sbjct: 1   MQIVVLAKVVPDYEVPSADFELVGNRAHPRYTRMIGLYDENAVELGVQLKEK-LGADLTV 59

Query: 64  VSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKE-KVDLVLL 122
           VS G     + +R ALAMGAD+ + VE      +   P  +A  L    +++  VDL+L 
Sbjct: 60  VSYGRNDDVQFLRKALAMGADKVVLVE-----GDSDDPYVIAANLKDAIDRQGTVDLILA 114

Query: 123 GKQAIDDDCNQTGQMTAGFLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKLPAVVT 182
           G+Q+ D D      + AG LD P    A  V       K+ +  + G   L+L    V++
Sbjct: 115 GRQSSDMDRGVVPGVLAGMLDLPFVPQACSVESVDGGWKISQITETGKRLLKLSGKGVLS 174

Query: 183 -ADLRLNEPRYATLPNIMKAKKKKIEVIKPGDLGVDLTSKLSV 224
              +  N PR   +  I  AKKK +E +     G    S+LSV
Sbjct: 175 ITSVPENVPRIPAVKAIFAAKKKPVEKLPEIGTGKMAVSELSV 217


>4XYJ-A nrPDB
          Length = 812

 Score = 35.9 bits (81), Expect = 0.018,   Method: Composition-based stats.
 Identities = 24/137 (17%), Positives = 49/137 (35%), Gaps = 8/137 (5%)

Query: 27  TGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVK------EVIAVSCGPAQCQETIRTALA 80
             +  D     M    + A+   + + +  +          +    G       + +ALA
Sbjct: 200 GSIDNDFCGTDMTIGTDSALHRIIEVVDAIMTTAQSHQRTFVLEVMGRHCGYLALVSALA 259

Query: 81  MGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAG 140
            GAD     E PP E          ++    A K++++++++ + AID            
Sbjct: 260 CGADWVFLPESPPEEG--WEEQMCVKLSENRARKKRLNIIIVAEGAIDTQNKPITSEKIK 317

Query: 141 FLDWPQGTFASQVTLEG 157
            L   Q  + ++VT+ G
Sbjct: 318 ELVVTQLGYDTRVTILG 334


>3JUK-A nrPDB
          Length = 281

 Score = 30.9 bits (68), Expect = 0.52,   Method: Composition-based stats.
 Identities = 44/253 (17%), Positives = 79/253 (31%), Gaps = 31/253 (12%)

Query: 14  IDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQE 73
                  R  P    +  + +     P  + AVEEA+         EV+A+  G      
Sbjct: 8   PAAGYGTRFLPITKTIPKEMLPIVDKPLIQYAVEEAME-----AGCEVMAIVTGRN---- 58

Query: 74  TIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQAIDDDCNQ 133
             + +L    D    +E       +   L+  R    + EK     V   +         
Sbjct: 59  --KRSLEDYFDTSYEIEHQIQGTNKENALKSIRN---IIEKCCFSYVRQKQMKGLGHAIL 113

Query: 134 TGQMTAGFLDWPQGTF-ASQVTLEGDKLKVEREIDGGLETLRLKLPAVVTADLRLNEPRY 192
           TG+   G  + P     A  + +  D   V +++    +  +  + A+    L     +Y
Sbjct: 114 TGEALIG--NEPFAVILADDLCISHDHPSVLKQMTSLYQKYQCSIVAIEEVALEE-VSKY 170

Query: 193 ATLPN---------IMKAKKKKIEVIKPGDLGV----DLTSKLSVISVEDPPQRTAGVKV 239
             +           I    +K  +   P +L V     LT  +  I  E  P +   +++
Sbjct: 171 GVIRGEWLEEGVYEIKDMVEKPNQEDAPSNLAVIGRYILTPDIFEILSETKPGKNNEIQI 230

Query: 240 ETTEDLVAKLKEI 252
                  AK K I
Sbjct: 231 TDALRTQAKRKRI 243


>6BX7-A nrPDB
          Length = 455

 Score = 30.9 bits (68), Expect = 0.54,   Method: Composition-based stats.
 Identities = 22/88 (25%), Positives = 36/88 (40%), Gaps = 10/88 (11%)

Query: 2   AELRVLVAVKRVIDYAVKIRVKPDRTGVVTDGVKHSMNPFCEIAVEEAVRL-----KEKK 56
           A  +V+V VK + D A  I ++        DG+ +      ++A E AV L     +++ 
Sbjct: 313 ARAQVVVTVKDMNDNAPTIEIRGIGLVTHQDGMANI---SEDVAEETAVALVQVSDRDEG 369

Query: 57  LVKEVIAVSCGPAQCQETIRTALAMGAD 84
               V  V  G       +R A   G+D
Sbjct: 370 ENAAVTCVVAG--DVPFQLRQASETGSD 395


>3C2O-A nrPDB
          Length = 294

 Score = 30.1 bits (66), Expect = 0.86,   Method: Composition-based stats.
 Identities = 25/157 (15%), Positives = 47/157 (29%), Gaps = 16/157 (10%)

Query: 23  KPDRTGVVTDGVKHSMNPFCEIAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMG 82
           + D T  +++ V      F          LKE  L  +   + CG    QE         
Sbjct: 14  RQDVTNWLSEDVPS----FDFGGYVVGSDLKEANLYCKQDGMLCGVPFAQEVFNQC---- 65

Query: 83  ADRGIHVEVPPAEAERLGPL--QVARVLAKLAEKEKVDLVLLGKQAIDDDCNQTGQMTAG 140
               + VE    E   L P      +++         +++L  + A++     +G  TA 
Sbjct: 66  ---ELQVEWLFKEGSFLEPSKNDSGKIVVAKITGPAKNILLAERTALNILSRSSGIATAS 122

Query: 141 FLDWPQGTFASQVTLEGDKLKVEREIDGGLETLRLKL 177
                  + A     +G      +   G     +  +
Sbjct: 123 H---KIISLARSTGYKGTIAGTRKTTPGLRRLEKYSM 156


>1RNL-A nrPDB
          Length = 215

 Score = 27.8 bits (60), Expect = 4.2,   Method: Composition-based stats.
 Identities = 27/130 (20%), Positives = 47/130 (36%), Gaps = 15/130 (11%)

Query: 44  IAVEEAVRLKEKKLVKEVIAVSCGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQ 103
             +E   +L+EK L   ++  S   +  +E + TAL  GAD  +  ++ P   E L    
Sbjct: 65  NGLETLDKLREKSLSGRIVVFSV--SNHEEDVVTALKRGADGYLLKDMEP---EDLLKAL 119

Query: 104 VARVLAKLAEKEKVDLVLLG-----KQAIDDDCNQTGQMTAGFL-----DWPQGTFASQV 153
                 ++   E +  VL       +   + D NQ        L       P    A ++
Sbjct: 120 HQAAAGEMVLSEALTPVLAASLRANRATTERDVNQLTPRERDILKLIAQGLPNKMIARRL 179

Query: 154 TLEGDKLKVE 163
            +    +KV 
Sbjct: 180 DITESTVKVH 189


>4LRT-B nrPDB
          Length = 323

 Score = 27.8 bits (60), Expect = 5.3,   Method: Composition-based stats.
 Identities = 17/88 (19%), Positives = 22/88 (25%), Gaps = 6/88 (6%)

Query: 66  CGPAQCQETIRTALAMGADRGIHVEVPPAEAERLGPLQVARVLAKLAEKEKVDLVLLGKQ 125
            G     E +  A  +G +          E + L  L      AK            G  
Sbjct: 54  VGVDPASEGLARARKLGVEASAEGVDWLLEQDELPDLVFEATSAKAHLANAPRYAEAGIT 113

Query: 126 AIDDDCNQTGQM------TAGFLDWPQG 147
           AID      G +          LD P  
Sbjct: 114 AIDLTPAAVGPLVCPPVNLTEHLDAPNV 141


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.305    0.126    0.299 

Lambda     K      H
   0.267   0.0387    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 7,596,420
Number of Sequences: 36641
Number of extensions: 252283
Number of successful extensions: 941
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 895
Number of HSP's gapped (non-prelim): 34
length of query: 255
length of database: 10,336,785
effective HSP length: 95
effective length of query: 160
effective length of database: 6,855,890
effective search space: 1096942400
effective search space used: 1096942400
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 58 (27.0 bits)