BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P38115 (344 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4IJC-A nrPDB 709 0.0 1ZUA-X nrPDB 191 3e-49 4GIE-A nrPDB 186 2e-47 5JH1-A nrPDB 179 2e-45 3H7U-A nrPDB 178 3e-45 1HQT-A nrPDB 170 7e-43 3G1R-A nrPDB 169 2e-42 3WCZ-A nrPDB 169 2e-42 2ALR-A nrPDB 168 2e-42 1FRB-A nrPDB 168 3e-42 3H7R-A nrPDB 168 4e-42 1Q5M-A nrPDB 167 5e-42 4GAC-A nrPDB 167 5e-42 4F40-A nrPDB 165 3e-41 1VBJ-A nrPDB 164 5e-41 2HE8-A nrPDB 164 6e-41 2FVL-A nrPDB 164 8e-41 1QWK-A nrPDB 162 2e-40 4JQA-A nrPDB 162 2e-40 4HBK-A nrPDB 161 3e-40 1C9W-A nrPDB 160 8e-40 1AFS-A nrPDB 160 9e-40 1MZR-A nrPDB 158 4e-39 5UXF-A nrPDB 156 1e-38 1DLA-A nrPDB 156 2e-38 5JM5-A nrPDB 154 6e-38 3RX4-A nrPDB 154 6e-38 3O3R-A nrPDB 153 1e-37 2BGQ-A nrPDB 152 2e-37 3KRB-A nrPDB 147 7e-36 3D3F-A nrPDB 147 7e-36 1VP5-A nrPDB 142 2e-34 5Z6T-A nrPDB 142 2e-34 1K8C-A nrPDB 142 3e-34 4OTK-A nrPDB 135 3e-32 5ZCM-A nrPDB 130 6e-31 4H8N-A nrPDB 121 5e-28 1A80-A nrPDB 119 2e-27 4MHB-A nrPDB 109 2e-24 3UP8-A nrPDB 109 2e-24 3WG6-A nrPDB 102 3e-22 1PYF-A nrPDB 58 5e-09 1PZ1-A nrPDB 56 2e-08 3N6Q-A nrPDB 49 3e-06 1LQA-A nrPDB 37 0.010 3EB3-A nrPDB 37 0.018 4R9O-A nrPDB 31 0.91 6F88-A nrPDB 30 1.8 5LIV-A nrPDB 30 1.9 3AU7-A nrPDB 30 2.1 6M9Z-A nrPDB 30 2.1 1Z6T-A nrPDB 30 2.2 3AMU-A nrPDB 30 2.3 4D10-D nrPDB 29 3.4 4D0P-A nrPDB 29 3.6 1GVE-A nrPDB 29 3.9 1L9G-A nrPDB 28 4.2 2PPQ-A nrPDB 28 4.3 5C5V-A nrPDB 28 4.4 5HTX-A nrPDB 28 5.8 5CUY-A nrPDB 28 6.1 6APH-A nrPDB 27 9.6 >4IJC-A nrPDB Length = 344 Score = 709 bits (1830), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/344 (100%), Positives = 344/344 (100%) Query: 1 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA 60 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA Sbjct: 1 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA 60 Query: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKAL 120 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKAL Sbjct: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKAL 120 Query: 121 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD 180 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD Sbjct: 121 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD 180 Query: 181 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY 240 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY Sbjct: 181 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY 240 Query: 241 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS 300 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS Sbjct: 241 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS 300 Query: 301 LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY 344 LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY Sbjct: 301 LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY 344 >1ZUA-X nrPDB Length = 317 Score = 191 bits (486), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 113/307 (36%), Positives = 179/307 (58%), Gaps = 28/307 (9%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 + L+ ++P +GLGT L + K+AVK AI AGYRHID A+ Y+ E VGEAI+E Sbjct: 5 FVELSTKAKMPIVGLGTWK--SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQE 62 Query: 84 LLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 +++ ++KREDLFI +K+WP ++ V ++ ++LK L L Y+D+ L HWP F+ Sbjct: 63 KIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFK---- 118 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 SG P DD G + +L+ ++ +E++ ++ V+A+GVSNFS +E+ Sbjct: 119 ----SGDDLFPKDDKGNAI-GGKATFLDAWEAMEELV---DEGLVKALGVSNFSHFQIEK 170 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------L 251 L+ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P L Sbjct: 171 LLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLL 230 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQEL 309 + P +K++A K+ T +LI +HI++ IVIP+S+ P RI +I+ L+ +E+ + Sbjct: 231 EDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATI 290 Query: 310 NDFGEKY 316 F + Sbjct: 291 LSFNRNW 297 >4GIE-A nrPDB Length = 290 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 112/294 (38%), Positives = 169/294 (57%), Gaps = 42/294 (14%) Query: 26 SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 +L+N VR+P LGLG + AET AV+ AI+AGYRHIDTA+ Y E VG+ I+E Sbjct: 17 TLHNSVRMPQLGLGVWRAQDG-AETANAVRWAIEAGYRHIDTAYIYSNERGVGQGIRE-- 73 Query: 86 EDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 + RE++++TTKVW +++ + S + LGLEY+DL L HWP Sbjct: 74 --SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWP---------- 121 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 GK +++T+K LEK+Y + +VRAIGVSNF +L L Sbjct: 122 -------------GKK------KFVDTWKALEKLY---EEKKVRAIGVSNFEPHHLTELF 159 Query: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS-HGAPNLKIPLVKKLAEK 262 K C+++P VNQVE HP Q LR+FC H+I +TA+SPLGS A LK ++ ++A+K Sbjct: 160 KSCKIRPMVNQVELHPLFQQRTLREFCKQHNIAITAWSPLGSGEEAGILKNHVLGEIAKK 219 Query: 263 YNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFA--SLTKDELQELNDFGE 314 +N + ++I + I+ G + IP+S N RI + LT++E++++++ E Sbjct: 220 HNKSPAQVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNE 273 >5JH1-A nrPDB Length = 309 Score = 179 bits (453), Expect = 2e-45, Method: Compositional matrix adjust. Identities = 119/315 (37%), Positives = 172/315 (54%), Gaps = 37/315 (11%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 +F LN G +IP++GLG+ + AV AA+KAGYRHID A Y E +G A+K+ Sbjct: 3 HFVLNTGAKIPSVGLGSWQSDPGV--VGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 84 LLEDGSIKREDLFITTKVW-----PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEK 138 L E+G +KRED+FIT+K+W P ++V +LN+SL L LEY+DL L HWP +K Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAP---EDVPEALNDSLNDLQLEYLDLYLIHWPFRVKK 117 Query: 139 IKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEY 198 G +P + D+ T+ +EK+Y + + RAIGVSNFS + Sbjct: 118 --------GTNTSPEN-------FVTPDFPATWGAMEKLY---DAGKARAIGVSNFSSKK 159 Query: 199 LERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-----LKI 253 L L+ RV P V+QVE HP Q +L FC + LTAYSPLGS G LK Sbjct: 160 LGDLLAVARVPPAVDQVECHPGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGNVLKE 219 Query: 254 PLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQELND 311 P++ +AEK T + + ++I+ G V+P+S N RI +++ S+ D L + ++ Sbjct: 220 PIIISIAEKLGKTSAQVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSE 279 Query: 312 FGEKYPVR--FIDEP 324 + +R FI P Sbjct: 280 IKQARLLRGNFIVNP 294 >3H7U-A nrPDB Length = 335 Score = 178 bits (452), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 114/283 (40%), Positives = 153/283 (54%), Gaps = 26/283 (9%) Query: 17 HPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPF 76 H +F LN G + P++GLGT L AV AA+K GYRHID A Y E Sbjct: 20 HMANAITFFKLNTGAKFPSVGLGTWQASPGL--VGDAVAAAVKIGYRHIDCAQIYGNEKE 77 Query: 77 VGEAIKELLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPL 134 +G +K+L ED +KREDLFIT+K+W D +V +LN +LK L LEYVDL L HWP Sbjct: 78 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 137 Query: 135 CFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNF 194 +K GI PVD T+K +E +Y + + RAIGVSNF Sbjct: 138 RIKK--GSVGIKPENLLPVDIP------------STWKAMEALY---DSGKARAIGVSNF 180 Query: 195 SIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKI- 253 S + L L++ RV P VNQVE HP Q +L++FC + L+AYSPLGS G LK Sbjct: 181 STKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD 240 Query: 254 ----PLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRI 292 P++ +AEK + + + + ++ G V+P+S N RI Sbjct: 241 VLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRI 283 >1HQT-A nrPDB Length = 326 Score = 170 bits (431), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 111/308 (36%), Positives = 174/308 (56%), Gaps = 29/308 (9%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 L+ G ++P +GLGT + + K A+K A+ GYRHID A + E +GEA++E + Sbjct: 9 LHTGQKMPLIGLGTWK--SEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQETVG 66 Query: 87 DG-SIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 G ++ RE+LF+T+K+W ++V+ +L ++L L LEY+DL L HWP FE+ +P Sbjct: 67 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP- 125 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 P + G Y A Y +T+K LE + VRA+G+SNFS ++ ++ Sbjct: 126 -------FPKNADGTIRYDAT-HYKDTWKALEALV---AKGLVRALGLSNFSSRQIDDVL 174 Query: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA----PN----LKIPL 255 V+P V QVE HP+L Q EL C + +TAYSPLGS PN L+ P+ Sbjct: 175 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPV 234 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLT--KDELQELNDFG 313 V+ LAEKYN + +L+ + +++ I IP+S+ P RI +I+ T +E+++L+ Sbjct: 235 VQALAEKYNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALN 294 Query: 314 EKYPVRFI 321 + +RFI Sbjct: 295 KN--LRFI 300 >3G1R-A nrPDB Length = 346 Score = 169 bits (428), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 109/313 (34%), Positives = 177/313 (56%), Gaps = 31/313 (9%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQA--VKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 L++G IP +GLGT + + + A VK AI GYRHID A+ Y+ E VGEAI+E Sbjct: 32 LSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAIREK 91 Query: 85 LEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + +G ++RED+F K+W + + V +L +L+ L L+YVDL + P+ F+ Sbjct: 92 IAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFK----- 146 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 G P D++GK +Y + T++ +E + V+++GVSNF+ LE + Sbjct: 147 ---PGDEIYPRDENGKWLY-HKSNLCATWEAMEAC---KDAGLVKSLGVSNFNRRQLELI 199 Query: 203 IKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS---------HGAPNL 251 + + + KP NQVE HP+ Q +L KFC HDI++TAYSPLG+ P L Sbjct: 200 LNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLL 259 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQEL 309 K L+ L ++YN T +++ ++I++G +VIP+S N RI + + SLT++E++++ Sbjct: 260 KDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDI 319 Query: 310 NDFGEKYPVRFID 322 + VRF++ Sbjct: 320 EALNKN--VRFVE 330 >3WCZ-A nrPDB Length = 308 Score = 169 bits (428), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 115/318 (36%), Positives = 164/318 (51%), Gaps = 49/318 (15%) Query: 25 FSLNNGVRIPALGLGT----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEA 80 LN+G IP + LGT A + + E +QAV AI+AGYRHIDTA Y+ E VG+ Sbjct: 8 IQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQDEEQVGQG 67 Query: 81 IKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEK 138 I E + +G + RE+LF+TTK+W D+V +L ESLK LGL+Y+DL L H+P+ + Sbjct: 68 IAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIHFPIATKP 127 Query: 139 IKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHR----VRAIGVSNF 194 P I DYLET++ ++ D R R+IGVSNF Sbjct: 128 DDSPDNI--------------------DYLETWQGMQ-------DARQLGLARSIGVSNF 160 Query: 195 SIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG---SHGA--- 248 + + RL+ ++P +NQ+E +P Q L C I + AYSP G S G Sbjct: 161 NATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQTGA 220 Query: 249 --PNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKD 304 P P + LA KY + +L+ Y I +G I IP+S N RI+ +I+ LT + Sbjct: 221 PPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQLTFE 280 Query: 305 ELQELNDFGEKYPVRFID 322 E+ +N F + + R ID Sbjct: 281 EVAAINQFNKNH--RVID 296 >2ALR-A nrPDB Length = 324 Score = 168 bits (426), Expect = 2e-42, Method: Compositional matrix adjust. Identities = 111/308 (36%), Positives = 173/308 (56%), Gaps = 29/308 (9%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 L+ G ++P +GLGT + + K AVK A+ GYRHID A Y EP +GEA+KE + Sbjct: 7 LHTGQKMPLIGLGTWK--SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 64 Query: 87 DG-SIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 G ++ RE+LF+T+K+W ++V+ +L ++L L LEY+DL L HWP FE+ +P Sbjct: 65 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP- 123 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 P + G Y + Y ET+K LE + V+A+G+SNF+ ++ ++ Sbjct: 124 -------FPKNADGTICYDST-HYKETWKALEALV---AKGLVQALGLSNFNSRQIDDIL 172 Query: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA----PN----LKIPL 255 V+P V QVE HP+L Q EL C + +TAYSPLGS P+ L+ P+ Sbjct: 173 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPV 232 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLT--KDELQELNDFG 313 V LAEKY + +L+ + +++ I IP+S+ P RI +I+ T +E+++LN Sbjct: 233 VLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALN 292 Query: 314 EKYPVRFI 321 + + R+I Sbjct: 293 KNW--RYI 298 >1FRB-A nrPDB Length = 315 Score = 168 bits (426), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 115/324 (35%), Positives = 188/324 (58%), Gaps = 40/324 (12%) Query: 24 YFSLNNGVRIPALGLGT--ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAI 81 + L+ ++P +GLGT + P++ K+AVKAAI AGYRHID A+AY E VGEAI Sbjct: 3 FVELSTKAKMPIVGLGTWKSPPNQ----VKEAVKAAIDAGYRHIDCAYAYCNENEVGEAI 58 Query: 82 KELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKI 139 +E +++ +++REDLFI +K+WP +++ + + ++L L L+Y+DL L HWP + Sbjct: 59 QEKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPG 118 Query: 140 KDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYL 199 K+ P DD G+ + + +LE ++ +E++ + V+A+GVSNF+ + Sbjct: 119 KE--------LFPKDDQGRIL-TSKTTFLEAWEGMEELV---DQGLVKALGVSNFNHFQI 166 Query: 200 ERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN------- 250 ERL+ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P+ Sbjct: 167 ERLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPS 226 Query: 251 -LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQ 307 L+ P +K++A K+ T +LI +HI++ +VIP+S+ P RI +I+ L+ +E+ Sbjct: 227 LLEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMA 286 Query: 308 ELNDFGEKYPVRFIDEPFAAILPE 331 + F + A +LPE Sbjct: 287 TILSFNRNW--------RACLLPE 302 >3H7R-A nrPDB Length = 331 Score = 168 bits (425), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 104/281 (37%), Positives = 155/281 (55%), Gaps = 30/281 (10%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 +F LN G ++P +GLGT A A++ AIK GYRHID A Y E +G +K+ Sbjct: 27 FFELNTGAKLPCVGLGT------YAMVATAIEQAIKIGYRHIDCASIYGNEKEIGGVLKK 80 Query: 84 LLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 L+ DG +KRE+LFIT+K+W L ++V ++L ++L+ L ++YVDL L HWP +K Sbjct: 81 LIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPASLKK--- 137 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 L+ TP D T+K +E +Y + + RAIGVSNFS + L Sbjct: 138 ----ESLMPTP-------EMLTKPDITSTWKAMEALY---DSGKARAIGVSNFSSKKLTD 183 Query: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSH--GAPNLKI---PLV 256 L+ RV P VNQVE HP Q L + C + L+ YSPLGS G LK+ P+V Sbjct: 184 LLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLKVLQNPIV 243 Query: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 ++AEK T + + + ++ G V+P+S + R+ +++ Sbjct: 244 TEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLD 284 >1Q5M-A nrPDB Length = 322 Score = 167 bits (424), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 110/323 (34%), Positives = 176/323 (54%), Gaps = 30/323 (9%) Query: 26 SLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 +L++G IP LG GT P E ++ +A K AI AG+RHID+A+ Y+ E VG AI+ Sbjct: 8 ALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEKEVGLAIRSK 67 Query: 85 LEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + DG++KRED+F T+K+W + V SL +SLK L L+YVDL + H+P + Sbjct: 68 IADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFPTALK----- 122 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 G+ P D+ GK ++ D T++ +EK + ++IGVSNF+ LE + Sbjct: 123 ---PGVEIIPTDEHGKAIFDT-VDICATWEAMEKC---KDAGLAKSIGVSNFNRRQLEMI 175 Query: 203 IKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN---------L 251 + + + KP NQVE HP+L Q +L +FC I+L AYS LGSH P L Sbjct: 176 LNKPGLKYKPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEWVDQSAPVLL 235 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQEL 309 + PL+ LA+K+ T + + Y +++G +V+ +S RI +I+ L ++++ + Sbjct: 236 EDPLIGALAKKHQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQLPSEDMKVI 295 Query: 310 NDFGEKYPVRFIDEPFAAILPEF 332 + + R++ FA P + Sbjct: 296 DSLNRNF--RYVTADFAIGHPNY 316 >4GAC-A nrPDB Length = 324 Score = 167 bits (423), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 109/308 (35%), Positives = 174/308 (56%), Gaps = 29/308 (9%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 L+ G ++P +GLGT + + K A+K A+ AGYRHID A Y E +GEA+KE + Sbjct: 7 LHTGQKMPLIGLGTWK--SEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEALKESVG 64 Query: 87 DG-SIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 G ++ RE+LF+T+K+W ++V+ +L ++L L LEY+DL L HWP FE+ +P Sbjct: 65 SGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP- 123 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 P + G Y + Y ET+K LE + V+A+G+SNF+ ++ ++ Sbjct: 124 -------FPKNADGTVRYDST-HYKETWKALEVLVAK---GLVKALGLSNFNSRQIDDVL 172 Query: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA----PN----LKIPL 255 V+P V QVE HP+L Q EL C + +TAYSPLGS P+ L+ P+ Sbjct: 173 SVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPVLLEEPV 232 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLT--KDELQELNDFG 313 V LAEK+ + +L+ + +++ I IP+S+NP RI +I+ T +E+++L+ Sbjct: 233 VLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMKQLDALN 292 Query: 314 EKYPVRFI 321 + + R+I Sbjct: 293 KNW--RYI 298 >4F40-A nrPDB Length = 288 Score = 165 bits (417), Expect = 3e-41, Method: Compositional matrix adjust. Identities = 100/277 (36%), Positives = 154/277 (55%), Gaps = 37/277 (13%) Query: 26 SLNNGVRIPALGLGT-ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 +L+NGV++P GLG +P ++ T+ AVK A+ AGYRHIDTA Y+ E VG ++ Sbjct: 14 TLSNGVKMPQFGLGVWQSPAGEV--TENAVKWALCAGYRHIDTAAIYKNEESVGAGLRA- 70 Query: 85 LEDGSIKREDLFITTKVWPVL--WDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + RED+FITTK+W ++ + ES + LG++Y+DL L HWP Sbjct: 71 ---SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWP--------- 118 Query: 143 KGISGLVKTPVDDSGKTMYAADGD-YLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 GK + + +G YL++++ E++Y + +VRAIGVSNF I +LE Sbjct: 119 -------------RGKDILSKEGKKYLDSWRAFEQLY---KEKKVRAIGVSNFHIHHLED 162 Query: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAE 261 ++ C V P VNQVE HP Q +LR FC I + A+SPLG L P++ + Sbjct: 163 VLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQ--GKLLSNPILSAIGA 220 Query: 262 KYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF 298 KYN T +++ ++I++ I IP+S++ RI + + Sbjct: 221 KYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADI 257 >1VBJ-A nrPDB Length = 281 Score = 164 bits (415), Expect = 5e-41, Method: Compositional matrix adjust. Identities = 108/299 (36%), Positives = 157/299 (52%), Gaps = 47/299 (15%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 L+NGV +P LG G + E + A AIK+GYRHIDTA Y+ E G AI Sbjct: 12 LKLSNGVMMPVLGFGMWKLQDG-NEAETATMWAIKSGYRHIDTAAIYKNEESAGRAIASC 70 Query: 85 LEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + RE+LF+TTK+W ++ + +S+K LGLEYVDL L HWP Sbjct: 71 ----GVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWP--------- 117 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 GK +++T+K EK+Y D +VRAIGVSNF ++E L Sbjct: 118 --------------GKD------KFIDTWKAFEKLYADK---KVRAIGVSNFHEHHIEEL 154 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG-SHGAPNLKIPLVKKLAE 261 +K C+V P VNQ+E HP L Q L ++C +I +TA+SPLG H + ++ K + Sbjct: 155 LKHCKVAPMVNQIELHPLLNQKALCEYCKSKNIAVTAWSPLGQGHLVEDARL---KAIGG 211 Query: 262 KYNVTGNDLLISYHIRQGTIVIPRSLNPVRI--SSSIEFASLTKDELQELNDF--GEKY 316 KY T +++ + I+ G I IP+S N RI + +I LT +++Q ++ G +Y Sbjct: 212 KYGKTAAQVMLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHRY 270 >2HE8-A nrPDB Length = 323 Score = 164 bits (414), Expect = 6e-41, Method: Compositional matrix adjust. Identities = 107/285 (37%), Positives = 158/285 (55%), Gaps = 26/285 (9%) Query: 27 LNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 LN+G IP LG GTA P E ++ K+ K AI AG+ H D+A Y TE VGEAI+ + Sbjct: 10 LNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRSKI 69 Query: 86 EDGSIKREDLFITTKVWPV-LWDEVDR-SLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 DG+++RED+F T+KVW L E+ R SL SL+ L +YVDL L H+P+ + Sbjct: 70 ADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALK------ 123 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 G PVD+ GK ++ D T++ +EK + ++IGVSNF+ LE ++ Sbjct: 124 --PGEENFPVDEHGKLIFDR-VDLCATWEAMEKC---KDAGLTKSIGVSNFNYRQLEMIL 177 Query: 204 KE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN---------LK 252 + + KP NQVE HP+L QM+L FC DI+L AY LG+ L Sbjct: 178 NKPGLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVLLD 237 Query: 253 IPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 P++ +A+KYN T + + Y +++G +V+ SL RI +++ Sbjct: 238 EPVLGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQ 282 >2FVL-A nrPDB Length = 324 Score = 164 bits (414), Expect = 8e-41, Method: Compositional matrix adjust. Identities = 113/333 (33%), Positives = 179/333 (53%), Gaps = 32/333 (9%) Query: 16 LHPKTTEIYFSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETE 74 + PK + LN+G +P LG GT P E + K AI+AG+RHID+A+ Y E Sbjct: 2 MDPKYQRV--ELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNE 59 Query: 75 PFVGEAIKELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHW 132 VG AI+ + DGS+KRED+F T+K+W + V +L SLK L L+YVDL L H+ Sbjct: 60 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 119 Query: 133 PLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVS 192 P+ + + P P D++GK ++ D T++ +EK + ++IGVS Sbjct: 120 PMALKPGETP--------LPKDENGKVIFDT-VDLSATWEVMEKC---KDAGLAKSIGVS 167 Query: 193 NFSIEYLERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA-- 248 NF+ LE ++ + + KP NQVE HP+L Q +L FC DI+L A+S LG+ Sbjct: 168 NFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKL 227 Query: 249 ---PN----LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--A 299 PN L+ P++ LA+K+ T + + Y +++G +V+ +S N RI +I+ Sbjct: 228 WVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEF 287 Query: 300 SLTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 LT ++++ L+ Y R++ F P++ Sbjct: 288 QLTSEDMKVLDGLNRNY--RYVVMDFLMDHPDY 318 >1QWK-A nrPDB Length = 317 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 115/328 (35%), Positives = 171/328 (52%), Gaps = 51/328 (15%) Query: 27 LNNGVRIPALGLGT--ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 L+NGV +P +GLGT ++P AE AVK A+KAGYR IDTA Y+ E +G AIKEL Sbjct: 10 LSNGVEMPVIGLGTWQSSP----AEVITAVKTAVKAGYRLIDTASVYQNEEAIGTAIKEL 65 Query: 85 LEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 LE+G +KRE+LFITTK W + +++ L ESLK L LEYVDL L H P F Sbjct: 66 LEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAAFN----- 120 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 +S + +PV+D ++Q + +Y +A+GVSN++ + + R Sbjct: 121 DDMSEHIASPVED--------------VWRQFDAVY---KAGLAKAVGVSNWNNDQISRA 163 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKK---- 258 + +QVE H + PQ + FC H+I +T+Y+ LGS G N +P +K Sbjct: 164 LALGLTPVHNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPTGQKLDWA 223 Query: 259 -------------LAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTK 303 LAEK + T +L+ Y + +G ++P+S+ RI + E SLT+ Sbjct: 224 PAPSDLQDQNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEVFDFSLTE 283 Query: 304 DELQELNDFGEKYPVRFIDEPFAAILPE 331 +++ +L + K R + F PE Sbjct: 284 EDIAKLEE--SKNSQRLFLQDFMTGHPE 309 >4JQA-A nrPDB Length = 331 Score = 162 bits (409), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 113/314 (35%), Positives = 173/314 (55%), Gaps = 36/314 (11%) Query: 27 LNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 LN+G +P LG GT P E ++ +AVK AI+AG+ HID+A Y E VG AI+ + Sbjct: 10 LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69 Query: 86 EDGSIKREDLFITTKVW-----PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 DGS+KRED+F T+K+W P L V +L SLK L L+YVDL L H+P+ + Sbjct: 70 ADGSVKREDIFYTSKLWSNSHRPEL---VRPALERSLKNLQLDYVDLYLIHFPVSVK--- 123 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 G P D++GK ++ D T++ +EK + ++IGVSNF+ LE Sbjct: 124 -----PGEEVIPKDENGKILFDT-VDLCATWEAMEKC---KDAGLAKSIGVSNFNHRLLE 174 Query: 201 RLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA-----PN--- 250 ++ + + KP NQVE HP+ Q +L FC DI+L AYS LGSH PN Sbjct: 175 MILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPV 234 Query: 251 -LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQ 307 L+ P++ LA+K+ T + + Y +++G +V+ +S N RI +++ LT +E++ Sbjct: 235 LLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMK 294 Query: 308 ELNDFGEKYPVRFI 321 ++ VR++ Sbjct: 295 AIDGLNRN--VRYL 306 >4HBK-A nrPDB Length = 344 Score = 161 bits (408), Expect = 3e-40, Method: Compositional matrix adjust. Identities = 97/295 (32%), Positives = 167/295 (56%), Gaps = 23/295 (7%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 +NNG IP +GLGT N E AVK A++ GYRH+D A+ Y E +GEA++ Sbjct: 38 LKMNNGRSIPVIGLGTWN--SPPGEVGAAVKKALEIGYRHLDCAYVYRNEAEIGEALENA 95 Query: 85 LEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 L +KRED+FIT+K+W + + V ++ E+LK L L Y+DL L HWP+ + D Sbjct: 96 LNSLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNLRLNYLDLYLIHWPVPLKHGGD- 154 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 P D +G+ + + + +T+K++EK+ ++ V++IG+SNF+ ++ + Sbjct: 155 -------LFPTDSNGQ-LCLDNVPHEDTWKEMEKLV---DEGLVKSIGLSNFNKRQIQNI 203 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKI-----PLVK 257 ++ CR+KP Q+E H + P ++L ++ + +TAY+PLGS K+ P V Sbjct: 204 LEHCRIKPANLQIEIHANFPNIKLVEYAQSVGLTVTAYAPLGSPAHSPGKVNLLTKPCVL 263 Query: 258 KLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQELN 310 ++A ++ T +L+ Y +++ IV+P+S+ RI + + L+ +E+ ELN Sbjct: 264 EIAHRHKKTPAQVLLRYLLQRKLIVVPKSVTFKRIEENFQVFDFQLSNEEMHELN 318 >1C9W-A nrPDB Length = 315 Score = 160 bits (405), Expect = 8e-40, Method: Compositional matrix adjust. Identities = 110/322 (34%), Positives = 180/322 (55%), Gaps = 36/322 (11%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 + L+ ++P +GLGT + K+AVK AI AGYRHID A+AY E VGEAI+E Sbjct: 3 FVELSTKAKMPIVGLGTW--QSPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQE 60 Query: 84 LLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 +++ +++REDLFI +K+WP ++ + + ++L L L+Y+DL L HWP + K+ Sbjct: 61 KIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGKE 120 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 P DD G + + +L+ ++ +E++ ++ V+A+GVSNF+ +ER Sbjct: 121 --------LFPKDDQGNVL-TSKITFLDAWEVMEELV---DEGLVKALGVSNFNHFQIER 168 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------L 251 ++ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P L Sbjct: 169 ILNKPGLKHKPVTNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSLL 228 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQEL 309 + P +K++A K+ T +LI +HI++ +VIP+S+ P RI + + L+ E+ + Sbjct: 229 EDPKIKEIAAKHKKTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMATI 288 Query: 310 NDFGEKYPVRFIDEPFAAILPE 331 F + A +LPE Sbjct: 289 LGFNRNW--------RACLLPE 302 >1AFS-A nrPDB Length = 323 Score = 160 bits (404), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 104/309 (33%), Positives = 168/309 (54%), Gaps = 32/309 (10%) Query: 26 SLNNGVRIPALGLGTANPHEKLA--ETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 +LN+G IP LG GT P EK+A E +A K AI G+RH D+A+ YE E VG+AI+ Sbjct: 9 ALNDGNFIPVLGFGTTVP-EKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRS 67 Query: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 +EDG++KRED+F T+K+W + V L ++LK+ L+YVDL + H+P+ + Sbjct: 68 KIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ---- 123 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 G + P D+ GK ++ D +T++ +EK + ++IGVSNF+ LER Sbjct: 124 ----PGDIFFPRDEHGKLLFET-VDICDTWEAMEKC---KDAGLAKSIGVSNFNCRQLER 175 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------- 250 ++ + + KP NQVE H +L Q ++ +C DI+L +Y LGS Sbjct: 176 ILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVL 235 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRI---SSSIEFASLTKDELQ 307 L P++ +A+KY T + + Y +++G + + RS N RI + EF L ++++ Sbjct: 236 LDDPVLCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEF-QLASEDMK 294 Query: 308 ELNDFGEKY 316 L+ + Sbjct: 295 ALDGLNRNF 303 >1MZR-A nrPDB Length = 296 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 99/287 (34%), Positives = 151/287 (52%), Gaps = 38/287 (13%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 L +G +P LGLG + E A++ A++ GYR IDTA AY+ E VG+A+K Sbjct: 28 IKLQDGNVMPQLGLGVWQASNE--EVITAIQKALEVGYRSIDTAAAYKNEEGVGKALK-- 83 Query: 85 LEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKG 144 + S+ RE+LFITTK+W +L +SLK L L+Y+DL L HWP+ Sbjct: 84 --NASVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYIDLYLMHWPV---------- 131 Query: 145 ISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIK 204 P D Y+E +K + ++ + +++IGV NF I +L+RLI Sbjct: 132 -------PAIDH----------YVEAWKGMIEL---QKEGLIKSIGVCNFQIHHLQRLID 171 Query: 205 ECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKYN 264 E V P +NQ+E HP + Q +L + H I ++SPL G +++ LA+KY Sbjct: 172 ETGVTPVINQIELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYG 231 Query: 265 VTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQEL 309 T ++I +H+ G +VIP+S+ P RI+ + + L KDEL E+ Sbjct: 232 KTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEI 278 >5UXF-A nrPDB Length = 342 Score = 156 bits (394), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 105/322 (32%), Positives = 179/322 (55%), Gaps = 30/322 (9%) Query: 27 LNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 LN+G IPALG GT P E +++ +A A+ GYRH+DTA+AY+ E +G+AI+ + Sbjct: 29 LNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVDTAYAYQVEEEIGQAIQSAI 88 Query: 86 EDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 G +KREDLF+TTK+W + + V +L +SLK L L+YVDL + H+P+ + Sbjct: 89 AAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDYVDLYIMHYPVPMK------ 142 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 SG PV++ GK++ D+ +T+++LE+ + V++IGVSNF+ LER++ Sbjct: 143 --SGDNDFPVNEQGKSLLDT-VDFCDTWERLEEC---KDAGLVKSIGVSNFNHRQLERIL 196 Query: 204 KE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN---------LK 252 + + KP NQVE H +L Q +L +C DI+L AY LG+ L Sbjct: 197 NKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGALGTQRYKEWVDQNSPVLLN 256 Query: 253 IPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSL--NPVRISSSIEFASLTKDELQELN 310 P++ +A+K + + + Y I++G + + +S N +R + + L+ ++++ L+ Sbjct: 257 DPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMRENLQVFGFQLSPEDMKTLD 316 Query: 311 DFGEKYPVRFIDEPFAAILPEF 332 + + R++ F PE+ Sbjct: 317 GLNKNF--RYLPAEFLVDHPEY 336 >1DLA-A nrPDB Length = 314 Score = 156 bits (394), Expect = 2e-38, Method: Compositional matrix adjust. Identities = 109/287 (37%), Positives = 169/287 (58%), Gaps = 28/287 (9%) Query: 24 YFSLNNGVRIPALGLGT-ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 + L G ++P LGLGT +P K+ E AVK AI GYRHID A Y+ E VG ++ Sbjct: 2 HLVLYTGAKMPILGLGTWKSPPGKVTE---AVKVAIDLGYRHIDCAHVYQNENEVGLGLQ 58 Query: 83 ELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 E L+ +KREDLFI +K+W ++ V + +L+ L L+Y+DL L HWP F+ K Sbjct: 59 EKLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGK 118 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 DP P+D G + + D++ET++ +E++ ++ V+AIGVSNF+ +E Sbjct: 119 DP--------FPLDGDGNVV-PDESDFVETWEAMEELV---DEGLVKAIGVSNFNHLQVE 166 Query: 201 RLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-------- 250 +++ + + KP VNQ+E HP+L Q +L ++C I++TAYSPLGS P Sbjct: 167 KILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSL 226 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 L+ P +K +A KYN T +LI + +++ IVIP+S+ P RI+ + + Sbjct: 227 LEDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQ 273 >5JM5-A nrPDB Length = 332 Score = 154 bits (389), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 104/300 (34%), Positives = 165/300 (55%), Gaps = 28/300 (9%) Query: 27 LNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 LN+G +P LG GT P E ++ + K AI+AG+RHID+A Y E VG AI+ + Sbjct: 10 LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69 Query: 86 EDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 DGS+KRED+F T+K+W + V +L SLK L+YVDL L H P+ + Sbjct: 70 ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK------ 123 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 G +P D++GK ++ D T++ +EK + ++IGVSNF+ LE ++ Sbjct: 124 --PGEELSPTDENGKVIFDI-VDLCTTWEAMEKC---KDAGLAKSIGVSNFNRRQLEMIL 177 Query: 204 KE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHG-----APN----LK 252 + + KP NQVE HP+ + +L FC DI+L AYS LGS PN L+ Sbjct: 178 NKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLE 237 Query: 253 IPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQELN 310 P++ LA+K+ T + + Y +++G +V+ +S N RI +++ LT ++++ ++ Sbjct: 238 DPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAID 297 >3RX4-A nrPDB Length = 336 Score = 154 bits (388), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 107/284 (37%), Positives = 170/284 (59%), Gaps = 28/284 (9%) Query: 27 LNNGVRIPALGLGT-ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 LNNG ++P LGLGT +P ++ E AVK AI GYRHID A Y+ E VG AI+E L Sbjct: 27 LNNGAKMPILGLGTWKSPPGQVTE---AVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 83 Query: 86 EDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 + +KRE+LFI +K+W ++ V + ++L L L+Y+DL L HWP F+ K+ Sbjct: 84 REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKE-- 141 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 P+D+SG + +D + L+T+ +E++ ++ V+AIG+SNF+ +E ++ Sbjct: 142 ------FFPLDESGNVV-PSDTNILDTWAAMEELV---DEGLVKAIGISNFNHLQVEMIL 191 Query: 204 KE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------LKI 253 + + KP VNQ+E HP+L Q +L ++C I++TAYSPLGS P L+ Sbjct: 192 NKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLED 251 Query: 254 PLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 P +K +A K+N T +LI + +++ +VIP+S+ P RI+ + + Sbjct: 252 PRIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFK 295 >3O3R-A nrPDB Length = 316 Score = 153 bits (386), Expect = 1e-37, Method: Compositional matrix adjust. Identities = 100/286 (34%), Positives = 164/286 (57%), Gaps = 26/286 (9%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 + L ++P +GLGT + K+AVKAAI AGYRH D A+ Y+ E VGEAI+E Sbjct: 4 FVKLRTKAKMPLVGLGTWK--SPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQE 61 Query: 84 LLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 +++ +++REDLFI +K+W +++ + + ++L L L+Y+DL L HWP + Sbjct: 62 KIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQ---- 117 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 +G P D GK + + +L+ ++ +E++ + V+A+GVSNF+ +ER Sbjct: 118 ----AGKEFLPKDSQGKVLM-SKSTFLDAWEGMEELV---DQGLVKALGVSNFNHFQIER 169 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------L 251 L+ + + KP NQVE HP+L Q +L ++C I + AYSPLGS P L Sbjct: 170 LLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVVL 229 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 +IP +K++A K+ T +LI +H+++ VIP+S+ I +I+ Sbjct: 230 EIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQ 275 >2BGQ-A nrPDB Length = 344 Score = 152 bits (385), Expect = 2e-37, Method: Compositional matrix adjust. Identities = 101/282 (35%), Positives = 155/282 (54%), Gaps = 33/282 (11%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAI-KAGYRHIDTAWAYETEPFVGEAIK 82 +F L +G +PA+GLGT ++T +V+ AI +AGYRH+DTA Y E VG+ +K Sbjct: 39 HFVLKSGHAMPAVGLGTWRAG---SDTAHSVRTAITEAGYRHVDTAAEYGVEKEVGKGLK 95 Query: 83 ELLEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 +E G I R+DLF+T+K+W + + V +L +LK L L+Y+DL HWP ++K Sbjct: 96 AAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPF---RLK 151 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLE-----TYKQLEKIYLDPNDHRVRAIGVSNFS 195 D G M G+ LE +K++E + D V+ IGV N++ Sbjct: 152 D---------------GAHMPPEAGEVLEFDMEGVWKEMENLV---KDGLVKDIGVCNYT 193 Query: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPL 255 + L RL++ ++ P V Q+E HP ++ + C H I +TAYSPLGS P+ Sbjct: 194 VTKLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHITAYSPLGSSEKNLAHDPV 253 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 V+K+A K N T +LI + +++GT VIP+S RI +I+ Sbjct: 254 VEKVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQ 295 >3KRB-A nrPDB Length = 334 Score = 147 bits (371), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 101/330 (30%), Positives = 167/330 (50%), Gaps = 53/330 (16%) Query: 34 PALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGS--IK 91 P LG GT + +T AV+ A+ GYRHID A+ Y+ E +G A ++ +D S IK Sbjct: 26 PRLGFGTWQAPPEAVQT--AVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIK 83 Query: 92 REDLFITTKVW-----PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEK-------I 139 RED++IT+K+W P L V +++ L ++Y+DL L HWPL F + Sbjct: 84 REDVWITSKLWNYNHRPEL---VREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGDLFP 140 Query: 140 KDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYL 199 KD +G + L K P+ D T++ +E++ + V+ IGVSN+++ L Sbjct: 141 KDAEGRAMLEKVPLAD--------------TWRAMEQLV---EEGLVKHIGVSNYTVPLL 183 Query: 200 ERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPL-GSHGAPN-------- 250 L+ ++KP VNQ+E HP P KFC + I +TAYSP+ GS+ P Sbjct: 184 ADLLNYAKIKPLVNQIEIHPWHPNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKN 243 Query: 251 --LKIPLVKKLAEKYNVTGNDLLISYHIRQGTI----VIPRSLNPVRISSSIEFA--SLT 302 L+ +K +A+ + + + +++H+++ VIP+S P RI ++ + L+ Sbjct: 244 VILECKTLKAIADAKGTSPHCVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLS 303 Query: 303 KDELQELNDFGEKYPVRFIDEPFAAILPEF 332 D++ +N+ +RF D +P F Sbjct: 304 DDDMDAINNIHLNKRIRFCDPAIFWKVPLF 333 >3D3F-A nrPDB Length = 275 Score = 147 bits (371), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 109/293 (37%), Positives = 156/293 (53%), Gaps = 44/293 (15%) Query: 18 PKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFV 77 P + + L+NGV +P GLG E E ++VKAAIK GYR IDTA Y+ E V Sbjct: 1 PTSLKDTVKLHNGVEMPWFGLGVFKV-ENGNEATESVKAAIKNGYRSIDTAAIYKNEEGV 59 Query: 78 GEAIKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLC 135 G IKE + RE+LFIT+KVW ++ + +SL+ L L+Y+DL L HWP Sbjct: 60 GIGIKE----SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-- 113 Query: 136 FEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFS 195 GK Y +T++ LEK+Y D ++RAIGVSNF Sbjct: 114 ---------------------GKDKYK------DTWRALEKLY---KDGKIRAIGVSNFQ 143 Query: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPL 255 + +LE L+K+ +KP VNQVE HP L Q ELR +C I L A+SPL L + Sbjct: 144 VHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQ--GQLLDNEV 201 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLTKDELQE 308 + ++AEK+N + +++ + ++ G + IP+S+ RI IE A + EL + Sbjct: 202 LTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRI---IENADIFDFELSQ 251 >1VP5-A nrPDB Length = 298 Score = 142 bits (358), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 99/305 (32%), Positives = 154/305 (50%), Gaps = 46/305 (15%) Query: 15 MLHPKTTEIYFSLNNGVRIPALGLGTAN-PHEKLAETKQAVKAAIKAGYRHIDTAWAYET 73 M PK T LNNGV +P LG G P EK T++ V AIK GYR IDTA +Y Sbjct: 13 MQVPKVT-----LNNGVEMPILGYGVFQIPPEK---TEECVYEAIKVGYRLIDTAASYMN 64 Query: 74 EPFVGEAIKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQH 131 E VG AIK +++G ++RE+LF+TTK+W V ++ ++ +SLK L LEY+DL L H Sbjct: 65 EEGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIH 124 Query: 132 WPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGV 191 P GD +K +E++Y D VRAIGV Sbjct: 125 QPF------------------------------GDVHCAWKAMEEMY---KDGLVRAIGV 151 Query: 192 SNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNL 251 SNF + L L+ + P VNQ+E HP + E +F ++I A+ P Sbjct: 152 SNFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRKNIF 211 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQEL 309 + +++ +AEKY T +++ + ++G + IP+++ R+ +I LT+++++++ Sbjct: 212 QNGVLRSIAEKYGKTVAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKI 271 Query: 310 NDFGE 314 E Sbjct: 272 ATLDE 276 >5Z6T-A nrPDB Length = 343 Score = 142 bits (358), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 103/322 (31%), Positives = 158/322 (49%), Gaps = 38/322 (11%) Query: 18 PKTTEIYFS-------LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWA 70 P T IYF LN+G +PA+G G + + + AIK GYR D A Sbjct: 15 PTTENIYFQGHMPSIKLNSGYDMPAVGFGCWK--VDVDTCSEQIYRAIKTGYRLFDGAED 72 Query: 71 YETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLL 128 Y E VG +K+ +++G +KREDLF+T+K+W D V+++LN +L L ++YVDL Sbjct: 73 YANEKLVGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLF 132 Query: 129 LQHWPLCFEKI----KDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDH 184 L H+P+ F+ + K P G G D LET+K LEK+ Sbjct: 133 LIHFPVTFKFVPLEEKYPPGFYC-------GKGDNFDYEDVPILETWKALEKLV---KAG 182 Query: 185 RVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG 244 ++R+IGVSNF L L++ +KP+V QVE HP+L Q L +F I +TAYS G Sbjct: 183 KIRSIGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFG 242 Query: 245 SHG------------APNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRI 292 +P + +K +A K+ + +L+ + ++G +IP+S R+ Sbjct: 243 PQSFVELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRL 302 Query: 293 SSSIEFASLTKDELQELNDFGE 314 + + S DE Q+ D + Sbjct: 303 LENKDVNSFDLDE-QDFADIAK 323 >1K8C-A nrPDB Length = 322 Score = 142 bits (357), Expect = 3e-34, Method: Compositional matrix adjust. Identities = 103/306 (33%), Positives = 160/306 (52%), Gaps = 38/306 (12%) Query: 27 LNNGVRIPALGLGT---ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 L++G +P++G G AN A + V AIKAGYR D A Y E VG+ +K Sbjct: 10 LSSGHLMPSIGFGCWKLAN-----ATAGEQVYQAIKAGYRLFDGAEDYGNEKEVGDGVKR 64 Query: 84 LLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLCFEKI-- 139 +++G +KRE++F+T+K+W D V+ +LN++L L ++YVDL L H+P+ F+ + Sbjct: 65 AIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIAFKFVPI 124 Query: 140 --KDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIE 197 K P G G D LET+K LEK+ ++++IGVSNF Sbjct: 125 EEKYPPGFYC-------GDGNNFVYEDVPILETWKALEKLVA---AGKIKSIGVSNFPGA 174 Query: 198 YLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHG------APNL 251 L L++ +KP V QVE HP+L Q +L +F + +TAYS G L Sbjct: 175 LLLDLLRGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGRAL 234 Query: 252 KIP------LVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTK 303 P +K +A KYN T ++L+ + ++G VIP+S P R+ + F + LTK Sbjct: 235 NTPTLFAHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDLTK 294 Query: 304 DELQEL 309 ++ +E+ Sbjct: 295 EDFEEI 300 >4OTK-A nrPDB Length = 318 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 102/294 (34%), Positives = 143/294 (48%), Gaps = 45/294 (15%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 +LN+ +P LGLG A + ET++AV AA++ G R IDTA+AY E VG AI Sbjct: 49 ITLNDEHTMPVLGLGVAELSDD--ETERAVSAALEIGCRLIDTAYAYGNEAAVGRAIAA- 105 Query: 85 LEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + RE+LF+TTK+ + + SL LGL+YVDL L HWP Sbjct: 106 ---SGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWP--------- 153 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 PV G Y++ + + + + R+IGVSNF+ E +E L Sbjct: 154 -------APPV-----------GKYVDAWGGMIQ---SRGEGHARSIGVSNFTAENIENL 192 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEK 262 I V P VNQ+E HP L Q ELRK H ++ +Y PL L P V +A + Sbjct: 193 IDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLAL--GRLLDNPTVTSIASE 250 Query: 263 YNVTGNDLLISYHIRQGTIVIPRSLNPVRISSS-----IEFASLTKDELQELND 311 Y T +L+ ++++ G V+ RS P RI+S+ E A+ D L LND Sbjct: 251 YVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLND 304 >5ZCM-A nrPDB Length = 341 Score = 130 bits (328), Expect = 6e-31, Method: Compositional matrix adjust. Identities = 94/308 (30%), Positives = 149/308 (48%), Gaps = 40/308 (12%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 LN+G +P +G G A V AIK GYR D A Y +GE I L+ Sbjct: 26 LNSGYEMPLVGFGCWKVDN--ATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRALD 83 Query: 87 DGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKG 144 +G + R++LFIT+K+W D V+ +L + L + L+Y+DL L H+P+ F K Sbjct: 84 EGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAF------KF 137 Query: 145 ISGLVKTPVDDSGKTMYAADGD--------YLETYKQLEKIYLDPNDHRVRAIGVSNFSI 196 + K P Y DGD LET+K +EK+ + ++IG+SNFS Sbjct: 138 VPFEEKYP-----PAFYCGDGDNFHYEDVPLLETWKAMEKL---TKGGKAKSIGISNFSA 189 Query: 197 EYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIP-- 254 + L++ +KP V Q+E HP+L Q L ++ I +TAYS G LK Sbjct: 190 ALIYDLLRGAEIKPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKA 249 Query: 255 ----------LVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFA--SLT 302 + +A+KY T +L+ + ++ +IP+S NP R+ ++E +L+ Sbjct: 250 LDTPTLFEHKTITSIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLS 309 Query: 303 KDELQELN 310 K++ E++ Sbjct: 310 KEDFDEIS 317 >4H8N-A nrPDB Length = 310 Score = 121 bits (303), Expect = 5e-28, Method: Compositional matrix adjust. Identities = 109/342 (31%), Positives = 158/342 (46%), Gaps = 63/342 (18%) Query: 10 NIVENMLHPKTTEIYFSLNNGVRIP-ALGLGTANPHEKLAETKQAVKA--------AIKA 60 ++ ++ L PKT F +G I ALG GT K A+T V +K Sbjct: 3 HMTQSNLLPKT----FRTKSGKEISIALGTGT---KWKQAQTINDVSTELVDNILLGLKL 55 Query: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEV-------DRSL 113 G+RHIDTA AY T+ VGEA+K + RED+++TTK P W + S+ Sbjct: 56 GFRHIDTAEAYNTQKEVGEALKRT----DVPREDIWVTTKYSPG-WGSIKAYSKSPSDSI 110 Query: 114 NESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQ 173 +++L LG++YVDL L H P T G T+ A +E K Sbjct: 111 DKALAQLGVDYVDLFLIHSPFF---------------TTEQTHGYTLEQAWEALVEAKKA 155 Query: 174 LEKIYLDPNDHRVRAIGVSNFSIEYLERLIKEC---RVKPTVNQVETHPHLPQME--LRK 228 +VR IG+SN +I +LE+L P VNQ+E HP L + + Sbjct: 156 ----------GKVREIGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVR 205 Query: 229 FCFMHDILLTAYSPLG--SHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRS 286 FC H IL+ A+SPL + N +K+LAEKY T +L+ Y +++G + + S Sbjct: 206 FCQEHGILVEAFSPLAPLARVETNALAETLKRLAEKYKKTEAQVLLRYTLQRGILPVTTS 265 Query: 287 LNPVRISSSIEF--ASLTKDELQELNDFGEKYPVR-FIDEPF 325 R+ S+ LT +E+ E+N G+ P R F E F Sbjct: 266 SKESRLKESLNLFDFELTDEEVNEINKIGDANPYRAFFHEQF 307 >1A80-A nrPDB Length = 277 Score = 119 bits (298), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 85/273 (31%), Positives = 133/273 (48%), Gaps = 38/273 (13%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 LN+G IP LG G A+T++AV+ A++ GYRHIDTA Y E E + + Sbjct: 7 LNDGNSIPQLGYGVFK--VPPADTQRAVEEALEVGYRHIDTAAIYGNE----EGVGAAIA 60 Query: 87 DGSIKREDLFITTKVWPVL--WDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKG 144 I R+DLFITTK+W DE ++ ESL L L+ VDL L HWP Sbjct: 61 ASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP----------- 109 Query: 145 ISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIK 204 TP D +Y+ ++++ ++ R+IGVSN + +LER++ Sbjct: 110 ------TPAAD----------NYVHAWEKMIELRA---AGLTRSIGVSNHLVPHLERIVA 150 Query: 205 ECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKYN 264 V P VNQ+E HP Q E+ + HD+ + ++ PLG V A + Sbjct: 151 ATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLGQGKYDLFGAEPVTAAAAAHG 210 Query: 265 VTGNDLLISYHIRQGTIVIPRSLNPVRISSSIE 297 T ++ +H+++G +V P+S+ R+ +++ Sbjct: 211 KTPAQAVLRWHLQKGFVVFPKSVRRERLEENLD 243 >4MHB-A nrPDB Length = 297 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 82/286 (28%), Positives = 133/286 (46%), Gaps = 43/286 (15%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 LNNG+ +P LG G AE ++AV AI+ GYR IDTA +Y+ E VG A+K Sbjct: 20 LNNGIAMPLLGFGVFQ-MTNTAECERAVIDAIETGYRLIDTAASYQNETQVGNALKL--- 75 Query: 87 DGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKG 144 I R++LFITTK+W ++ SL L L+YVDL L H P Sbjct: 76 -SGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYLIHQPY---------- 124 Query: 145 ISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIK 204 GD ++ +E+++ ++RAIGVSNF + L L+ Sbjct: 125 --------------------GDVHGAWRAMEELH---QAGKIRAIGVSNFHPDRLADLMA 161 Query: 205 ECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKYN 264 ++ P VNQ+E +P Q+ + I A++P + P++ + EKY Sbjct: 162 FNKIIPAVNQIEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRNGLFQNPVLTAIGEKYG 221 Query: 265 VTGNDLLISYHIRQGTIVIPRSLNPVRISSSI---EFASLTKDELQ 307 + +++ + ++G + + +S+ R+ +I +F +D LQ Sbjct: 222 KSVGQVVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDMLQ 267 >3UP8-A nrPDB Length = 298 Score = 109 bits (272), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 90/315 (28%), Positives = 148/315 (46%), Gaps = 54/315 (17%) Query: 7 STENI-VENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHI 65 TEN+ ++M+H ++ NG IPALG GT AE + + A+K G+RH+ Sbjct: 14 GTENLYFQSMMHAVSS-------NGANIPALGFGTFRMSG--AEVLRILPQALKLGFRHV 64 Query: 66 DTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLE 123 DTA Y E VGEAI++ I R D+F+TTKVW + D S++ESL+ L + Sbjct: 65 DTAQIYGNEAEVGEAIQK----SGIPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTD 120 Query: 124 YVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPND 183 +VDLLL HWP +D E L ++ N Sbjct: 121 HVDLLLLHWP----------------------------GSDVPMAERIGALNEVR---NA 149 Query: 184 HRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPL 243 +VR IG+SNF+ +E + NQVE HP+L Q ++ + + LT+Y + Sbjct: 150 GKVRHIGISNFNTTQMEEAARLSDAPIATNQVEYHPYLDQTKVLQTARRLGMSLTSYYAM 209 Query: 244 GSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHI-RQGTIVIPRSLNPVRISSS---IEFA 299 + P PL+ ++ ++ T + + + + +Q IV+ ++ R+ + +FA Sbjct: 210 ANGKVP--ADPLLTEIGGRHGKTAAQVALRWLVQQQDVIVLSKTATEARLKENFAIFDFA 267 Query: 300 SLTKDELQELNDFGE 314 LT++E+ + + Sbjct: 268 -LTREEMAAVRELAR 281 >3WG6-A nrPDB Length = 307 Score = 102 bits (254), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 91/324 (28%), Positives = 150/324 (46%), Gaps = 52/324 (16%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAET---KQAVKA---AIKAGYRHIDTAWAYETEPFVG 78 F L+NG +IPA+ GT + K KQ + A+++G+RHID A Y T +G Sbjct: 11 FKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEIYGTNKEIG 70 Query: 79 EAIKELLEDGSIKREDLFITTKVWPV--LWDEVD-------RSLNESLKALGLEYVDLLL 129 A+K + + R+D+FIT K +D +L L+ LGLEYVDL L Sbjct: 71 IALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLGLEYVDLYL 126 Query: 130 QHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAI 189 H+P EK + D +E ++ LE+ N+ R I Sbjct: 127 IHFPYISEK-----------------------SHGFDLVEAWRYLERA---KNEGLARNI 160 Query: 190 GVSNFSIEYLERLIK-ECRVKPTVNQVETHPHLPQME--LRKFCFMHDILLTAYSPLG-- 244 GVSNF+IE L+ ++ P VNQ+E +L + ++ IL+ AY PLG Sbjct: 161 GVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIEAYGPLGPI 220 Query: 245 SHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LT 302 + G P ++ KL+EKY +L+ + +++G + I + RI+ +E L Sbjct: 221 TQGRPGPLDKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVLEIFDFELD 280 Query: 303 KDELQELNDFGEKYPVRFIDEPFA 326 K++ ++ G++ +R + ++ Sbjct: 281 KEDEDQITKVGKEKTLRQFSKEYS 304 >1PYF-A nrPDB Length = 312 Score = 58.2 bits (139), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 63/233 (27%), Positives = 99/233 (42%), Gaps = 58/233 (24%) Query: 30 GVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAY---ETEPFVGEAIKELLE 86 G+ A+G P+ K+ V+ AI+ G +DTA+ Y +E +GE ++E Sbjct: 17 GLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF-- 74 Query: 87 DGSIKREDLFITTK----------VWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCF 136 RED+ I TK V+ D + +S++ESLK L +Y+DL H+P Sbjct: 75 ----NREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFPDE- 129 Query: 137 EKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSI 196 TP D++ + +++K ++R+IGVSNFS+ Sbjct: 130 -------------HTPKDEA-----------VNALNEMKKA------GKIRSIGVSNFSL 159 Query: 197 EYLERLIKECRVKPTVNQVETHPHLPQMELRKFCF----MHDILLTAYSPLGS 245 E L KE V+ ++ +L E K F H+I Y PL S Sbjct: 160 EQL----KEANKDGLVDVLQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVS 208 >1PZ1-A nrPDB Length = 333 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 75/269 (27%), Positives = 119/269 (44%), Gaps = 76/269 (28%) Query: 28 NNGVRIPALGLGT--------ANPHEKLAETKQAVKAAIKAGYRHIDTAWAY---ETEPF 76 + G+ +GLGT EK + + ++AA+ G IDTA AY ++E Sbjct: 8 DTGIEASRIGLGTWAIGGTMWGGTDEKT--SIETIRAALDQGITLIDTAPAYGFGQSEEI 65 Query: 77 VGEAIKELLEDGSIKREDLFITTKV---WP--VLWDEVDRS-----LNESLKALGLEYVD 126 VG+AIKE + KR+ + + TK W L+ +R+ + SLK L +Y+D Sbjct: 66 VGKAIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYID 120 Query: 127 LLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRV 186 L HWP DP LV P++++ + M +++Y + ++ Sbjct: 121 LYQVHWP-------DP-----LV--PIEETAEVM--------------KELY---DAGKI 149 Query: 187 RAIGVSNFSIEYLE--RLIKECR-VKPTVNQVETHPHLPQMELRKFCFMHDILLTA--YS 241 RAIGVSNFSIE ++ R + ++P N E +ME + D +T Y Sbjct: 150 RAIGVSNFSIEQMDTFRAVAPLHTIQPPYNLFER-----EMEESVLPYAKDNKITTLLYG 204 Query: 242 PLGSHGAPNLKIPLVKKLAEKYNVTGNDL 270 L + L K+ E+Y G+DL Sbjct: 205 SL-------CRGLLTGKMTEEYTFEGDDL 226 >3N6Q-A nrPDB Length = 346 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 40/118 (33%), Positives = 60/118 (50%), Gaps = 15/118 (12%) Query: 29 NGVRIPALGLGTAN--PHEKLAETKQAV-KAAIKAGYRHIDTAWAYETEPFVGEA--IKE 83 +G+R+PAL LG + H E+++A+ + A G H D A Y P E + Sbjct: 21 SGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGRL 80 Query: 84 LLEDGSIKREDLFITTK----VWPVLWDEVDR------SLNESLKALGLEYVDLLLQH 131 L ED + R++L I+TK +WP + SL++SLK +GLEYVD+ H Sbjct: 81 LREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSH 138 >1LQA-A nrPDB Length = 346 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 55/196 (28%), Positives = 77/196 (39%), Gaps = 53/196 (27%) Query: 28 NNGVRIPALGLGTANPHEKLAETKQAVKA--AIKAGYRHIDTAWAYE----------TEP 75 ++ + + LGLGT E+ +E + A+ G ID A Y TE Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 76 FVGEAIKELLEDGSIKREDLFITTKV--------------WPVLWDEVDRSLNESLKALG 121 +VG L + GS RE L I +KV + + +L++SLK L Sbjct: 68 YVG---NWLAKHGS--REKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQ 122 Query: 122 LEYVDLLLQHWPL----CFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKI 177 +Y+DL HWP CF K+ G S P T+ D L Y++ KI Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKL----GYSWTDSAPAVSLLDTL-----DALAEYQRAGKI 173 Query: 178 YLDPNDHRVRAIGVSN 193 R IGVSN Sbjct: 174 ---------RYIGVSN 180 >3EB3-A nrPDB Length = 327 Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust. Identities = 42/149 (28%), Positives = 66/149 (44%), Gaps = 37/149 (24%) Query: 29 NGVRIPALGLGT-----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAY---ETEPFVGEA 80 +G+R+ LGLGT +++AE + A G DTA Y + E +G Sbjct: 11 SGLRVSCLGLGTWVTFGGQITDEMAE--HLMTLAYDNGINLFDTAEVYAAGKAEVVLGNI 68 Query: 81 IKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNE---------SLKALGLEYVDLLLQH 131 IK+ +R L ITTK++ E +R L+ SL+ L LEYVD++ + Sbjct: 69 IKK----KGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN 124 Query: 132 WPLCFEKIKDPKGISGLVKTPVDDSGKTM 160 P DP TP++++ + M Sbjct: 125 RP-------DP-------NTPMEETVRAM 139 >4R9O-A nrPDB Length = 301 Score = 30.8 bits (68), Expect = 0.91, Method: Compositional matrix adjust. Identities = 47/174 (27%), Positives = 59/174 (33%), Gaps = 50/174 (28%) Query: 64 HIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLN--------- 114 H D Y+ E GEA L RE L I TK + L Sbjct: 54 HADIYGGYQCEAAFGEA----LTLAPHLREKLQIVTKCGIATTARAENKLGHYITDRRHI 109 Query: 115 -----ESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLE 169 +SLK L +Y+D+LL H P DP + AD D E Sbjct: 110 ILSAEQSLKNLATDYLDMLLIHRP-------DP-----------------LMDAD-DVAE 144 Query: 170 TYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHP-HLP 222 ++ L + +VR GVSNF+ L NQVE P H P Sbjct: 145 AFQHLHQ------SGKVRHFGVSNFTPAQFTLLQSRLPFTLATNQVEISPVHQP 192 >6F88-A nrPDB Length = 400 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 13/86 (15%) Query: 43 PHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW 102 P EKL ET + V+A ++ R D A E++ GE + + E ++RE Sbjct: 144 PAEKLHETDERVRAMLRGLVRMHDPAAVAESQRAYGETLGLITE--VVERES-------- 193 Query: 103 PVLWDEVDRSLNESLKALGLEYVDLL 128 D D L E L+ L E++D + Sbjct: 194 ---RDTSDTLLGEILRTLKAEHMDTI 216 >5LIV-A nrPDB Length = 450 Score = 29.6 bits (65), Expect = 1.9, Method: Compositional matrix adjust. Identities = 25/86 (29%), Positives = 39/86 (45%), Gaps = 13/86 (15%) Query: 43 PHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW 102 P EKL ET + V+A ++ R D A E++ GE + + E ++RE Sbjct: 194 PAEKLHETDERVRAMLRGLVRMHDPAAVAESQRAYGETLGLITE--VVERES-------- 243 Query: 103 PVLWDEVDRSLNESLKALGLEYVDLL 128 D D L E L+ L E++D + Sbjct: 244 ---RDTSDTLLGEILRTLKAEHMDTI 266 >3AU7-A nrPDB Length = 402 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW-PVLWDEVDRSLNESLKA 119 G +D A + +PF +AIK++L+ E LF+ K + P L + R L +L A Sbjct: 113 GAVFVDEELAVKLKPFADKAIKDVLQ----IDEALFVIGKYFIPHLRHKKGRGLIGALAA 168 Query: 120 LGLEYVDLLLQ 130 +G E D L+ Sbjct: 169 VGAELEDFTLE 179 >6M9Z-A nrPDB Length = 230 Score = 29.6 bits (65), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 18 PKTTEIY-FSLNNGVRIPALGLGTANPHEKLAETK 51 PKT E++ F NGV+ +G GT NP+E E K Sbjct: 4 PKTHELHIFGSFNGVKFDMVGEGTGNPNEGSEELK 38 >1Z6T-A nrPDB Length = 591 Score = 29.6 bits (65), Expect = 2.2, Method: Compositional matrix adjust. Identities = 17/54 (31%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 54 VKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWD 107 ++ + Y +D A + E + E IK+ D SI ++D+ + TKV +LWD Sbjct: 353 IRKSSSYDYEALDEAMSISVE-MLREDIKDYYTDLSILQKDVKVPTKVLCILWD 405 >3AMU-A nrPDB Length = 440 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 36/71 (50%), Gaps = 5/71 (7%) Query: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW-PVLWDEVDRSLNESLKA 119 G +D A + +PF +AIK++L+ E LF+ K + P L + R L +L A Sbjct: 113 GAVFVDEELAVKLKPFADKAIKDVLQID----EALFVIGKYFIPHLRHKKGRGLIGALAA 168 Query: 120 LGLEYVDLLLQ 130 +G E D L+ Sbjct: 169 VGAELEDFTLE 179 >4D10-D nrPDB Length = 410 Score = 28.9 bits (63), Expect = 3.4, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 123 EYVDLLLQHWPLCFEKIKDPKGISG-LVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181 E V + QH +EK +D + + LV P++ +G+ Y D LETY ++ ++YL+ Sbjct: 105 EQVASIRQHLASIYEKEEDWRNAAQVLVGIPLE-TGQKQYNVDYK-LETYLKIARLYLED 162 Query: 182 ND 183 +D Sbjct: 163 DD 164 >4D0P-A nrPDB Length = 387 Score = 28.9 bits (63), Expect = 3.6, Method: Compositional matrix adjust. Identities = 20/62 (32%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 123 EYVDLLLQHWPLCFEKIKDPKGISG-LVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181 E V + QH +EK +D + + LV P++ +G+ Y D LETY ++ ++YL+ Sbjct: 125 EQVASIRQHLASIYEKEEDWRNAAQVLVGIPLE-TGQKQYNVDYK-LETYLKIARLYLED 182 Query: 182 ND 183 +D Sbjct: 183 DD 184 >1GVE-A nrPDB Length = 327 Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust. Identities = 31/110 (28%), Positives = 48/110 (43%), Gaps = 14/110 (12%) Query: 34 PALGLGTANPHEKL--AETKQAVKAAIKAGYRHIDTAWAY---ETEPFVGEAIKELLEDG 88 PA LG ++ + +V+A ++ G+ IDTA+ Y ++E +G+ L G Sbjct: 6 PATVLGAMEMGRRMDVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSG 65 Query: 89 SIKREDLFITTKVWPVLWD-----EVDRSLNESLKALGLEYVDLLLQHWP 133 + I TK P+ +V L SLK L VDL H+P Sbjct: 66 CKVK----IATKAAPMFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFP 111 >1L9G-A nrPDB Length = 192 Score = 28.5 bits (62), Expect = 4.2, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 19/30 (63%), Gaps = 3/30 (10%) Query: 75 PFVGEA---IKELLEDGSIKREDLFITTKV 101 PFVG A + ELL + I+RED++I V Sbjct: 58 PFVGRAGMLLTELLRESGIRREDVYICNVV 87 >2PPQ-A nrPDB Length = 322 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 31/63 (49%), Gaps = 7/63 (11%) Query: 77 VGEAIKEL---LEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEY---VDLLLQ 130 VG+A+ + E IKR + ++ W VLWD+ + +E K L E +D L Sbjct: 121 VGKALAAMHLASEGFEIKRPNA-LSVDGWKVLWDKSEERADEVEKGLREEIRPEIDYLAA 179 Query: 131 HWP 133 HWP Sbjct: 180 HWP 182 >5C5V-A nrPDB Length = 342 Score = 28.5 bits (62), Expect = 4.4, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 20/50 (40%) Query: 45 EKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKRED 94 E KQ +K + Y+H D W Y P E+ + L E G D Sbjct: 172 ESFNPIKQDIKNGVPRFYKHGDMMWNYGAFPQTWESTEVLFEAGVTGDND 221 >5HTX-A nrPDB Length = 439 Score = 28.1 bits (61), Expect = 5.8, Method: Compositional matrix adjust. Identities = 10/30 (33%), Positives = 18/30 (60%) Query: 314 EKYPVRFIDEPFAAILPEFTGNGPNLDNLK 343 E YP + +P++ +LP+ G ++ NLK Sbjct: 189 ESYPSWLLGQPYSQLLPKVQAPGTSIGNLK 218 >5CUY-A nrPDB Length = 414 Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 19/44 (43%) Query: 45 EKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDG 88 E KQ +K + Y+H D W Y P E+ + L E G Sbjct: 244 ESFNPIKQDIKNGVPRFYKHGDMMWNYGAFPQTWESTEVLFEAG 287 >6APH-A nrPDB Length = 445 Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust. Identities = 13/28 (46%), Positives = 19/28 (67%), Gaps = 3/28 (10%) Query: 245 SHGAPNLKIPLVKKLAEKYNVTGNDLLI 272 +HGA ++I K +KYNV GND++I Sbjct: 327 NHGATKVEI---KPQVDKYNVNGNDIII 351 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4IJC-A nrPDB 491 e-139 1Q5M-A nrPDB 422 e-118 2FVL-A nrPDB 421 e-118 4JQA-A nrPDB 415 e-116 1ZUA-X nrPDB 414 e-116 5JM5-A nrPDB 407 e-114 2ALR-A nrPDB 400 e-112 4GAC-A nrPDB 398 e-111 1HQT-A nrPDB 396 e-111 5UXF-A nrPDB 396 e-111 2HE8-A nrPDB 394 e-110 3G1R-A nrPDB 394 e-110 1AFS-A nrPDB 384 e-107 3H7U-A nrPDB 378 e-105 1C9W-A nrPDB 376 e-105 3RX4-A nrPDB 376 e-105 1DLA-A nrPDB 375 e-104 5JH1-A nrPDB 375 e-104 1FRB-A nrPDB 374 e-104 4HBK-A nrPDB 367 e-102 3O3R-A nrPDB 363 e-101 3H7R-A nrPDB 360 e-100 5Z6T-A nrPDB 359 e-100 4GIE-A nrPDB 353 4e-98 5ZCM-A nrPDB 353 5e-98 1K8C-A nrPDB 352 1e-97 3WCZ-A nrPDB 351 3e-97 2BGQ-A nrPDB 344 4e-95 1VBJ-A nrPDB 343 9e-95 4F40-A nrPDB 340 6e-94 1VP5-A nrPDB 339 1e-93 3KRB-A nrPDB 338 2e-93 1MZR-A nrPDB 334 3e-92 1QWK-A nrPDB 330 5e-91 4MHB-A nrPDB 320 8e-88 3D3F-A nrPDB 313 6e-86 1A80-A nrPDB 299 1e-81 4OTK-A nrPDB 296 6e-81 3UP8-A nrPDB 286 1e-77 4H8N-A nrPDB 278 2e-75 3WG6-A nrPDB 276 7e-75 1PYF-A nrPDB 160 7e-40 1PZ1-A nrPDB 152 2e-37 3N6Q-A nrPDB 126 2e-29 Sequences not found previously or not previously below threshold: 1LQA-A nrPDB 102 2e-22 3EB3-A nrPDB 95 5e-20 4R9O-A nrPDB 90 2e-18 1OG6-A nrPDB 84 8e-17 2CLP-A nrPDB 67 1e-11 4EXA-A nrPDB 65 5e-11 1GVE-A nrPDB 63 1e-10 2BP1-A nrPDB 63 2e-10 2C91-A nrPDB 55 5e-08 1OM0-A nrPDB 33 0.16 5Z6Q-A nrPDB 33 0.25 2ZC8-A nrPDB 33 0.26 4EHI-A nrPDB 32 0.58 5Y0V-A nrPDB 30 1.3 5ZF1-A nrPDB 30 1.5 2FAW-A nrPDB 30 1.6 6ET0-A nrPDB 30 1.7 3Q3N-A nrPDB 29 2.4 3A13-A nrPDB 29 2.7 5GJU-A nrPDB 29 3.1 4K91-A nrPDB 29 3.8 3ANK-A nrPDB 28 4.2 6F0K-D nrPDB 28 5.8 3LCV-B nrPDB 28 6.2 4NPH-A nrPDB 28 7.4 4A35-A nrPDB 27 8.9 >4IJC-A nrPDB Length = 344 Score = 491 bits (1263), Expect = e-139, Method: Composition-based stats. Identities = 344/344 (100%), Positives = 344/344 (100%) Query: 1 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA 60 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA Sbjct: 1 MSSSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKA 60 Query: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKAL 120 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKAL Sbjct: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKAL 120 Query: 121 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD 180 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD Sbjct: 121 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD 180 Query: 181 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY 240 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY Sbjct: 181 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY 240 Query: 241 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS 300 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS Sbjct: 241 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS 300 Query: 301 LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY 344 LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY Sbjct: 301 LTKDELQELNDFGEKYPVRFIDEPFAAILPEFTGNGPNLDNLKY 344 >1Q5M-A nrPDB Length = 322 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 112/332 (33%), Positives = 178/332 (53%), Gaps = 32/332 (9%) Query: 17 HPKTTEIYFSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEP 75 PK +L++G IP LG GT P E ++ +A K AI AG+RHID+A+ Y+ E Sbjct: 1 DPKFQR--VALSDGHFIPVLGFGTYAPEEVPKSKAMEATKIAIDAGFRHIDSAYFYKNEK 58 Query: 76 FVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWP 133 VG AI+ + DG++KRED+F T+K+W + V SL +SLK L L+YVDL + H+P Sbjct: 59 EVGLAIRSKIADGTVKREDIFYTSKLWCTFHRPELVRPSLEDSLKNLQLDYVDLYIIHFP 118 Query: 134 LCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSN 193 + G+ P D+ GK ++ D T++ +EK + ++IGVSN Sbjct: 119 TALK--------PGVEIIPTDEHGKAIFDT-VDICATWEAMEKC---KDAGLAKSIGVSN 166 Query: 194 FSIEYLERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP-- 249 F+ LE ++ + + KP NQVE HP+L Q +L +FC I+L AYS LGSH P Sbjct: 167 FNRRQLEMILNKPGLKYKPVCNQVECHPYLNQGKLLEFCKSKGIVLVAYSALGSHREPEW 226 Query: 250 -------NLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--AS 300 L+ PL+ LA+K+ T + + Y +++G +V+ +S RI +I+ Sbjct: 227 VDQSAPVLLEDPLIGALAKKHQQTPALIALRYQLQRGIVVLAKSFTEKRIKENIQVFEFQ 286 Query: 301 LTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 L ++++ ++ + R++ FA P + Sbjct: 287 LPSEDMKVIDSLNRNF--RYVTADFAIGHPNY 316 >2FVL-A nrPDB Length = 324 Score = 421 bits (1082), Expect = e-118, Method: Composition-based stats. Identities = 111/333 (33%), Positives = 176/333 (52%), Gaps = 32/333 (9%) Query: 16 LHPKTTEIYFSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETE 74 + PK LN+G +P LG GT P E + K AI+AG+RHID+A+ Y E Sbjct: 2 MDPKYQR--VELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNE 59 Query: 75 PFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHW 132 VG AI+ + DGS+KRED+F T+K+W + V +L SLK L L+YVDL L H+ Sbjct: 60 EQVGLAIRSKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHF 119 Query: 133 PLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVS 192 P+ + + P P D++GK ++ D T++ +EK + ++IGVS Sbjct: 120 PMALKPGETP--------LPKDENGKVIFDT-VDLSATWEVMEKC---KDAGLAKSIGVS 167 Query: 193 NFSIEYLERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP- 249 NF+ LE ++ + + KP NQVE HP+L Q +L FC DI+L A+S LG+ Sbjct: 168 NFNYRQLEMILNKPGLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKL 227 Query: 250 --------NLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--A 299 L+ P++ LA+K+ T + + Y +++G +V+ +S N RI +I+ Sbjct: 228 WVDPNSPVLLEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEF 287 Query: 300 SLTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 LT ++++ L+ Y R++ F P++ Sbjct: 288 QLTSEDMKVLDGLNRNY--RYVVMDFLMDHPDY 318 >4JQA-A nrPDB Length = 331 Score = 415 bits (1068), Expect = e-116, Method: Composition-based stats. Identities = 111/324 (34%), Positives = 173/324 (53%), Gaps = 30/324 (9%) Query: 25 FSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 LN+G +P LG GT P E ++ +AVK AI+AG+ HID+A Y E VG AI+ Sbjct: 8 VKLNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRS 67 Query: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 + DGS+KRED+F T+K+W + V +L SLK L L+YVDL L H+P+ + Sbjct: 68 KIADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK---- 123 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 G P D++GK ++ D T++ +EK + ++IGVSNF+ LE Sbjct: 124 ----PGEEVIPKDENGKILFDT-VDLCATWEAMEKC---KDAGLAKSIGVSNFNHRLLEM 175 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP---------N 250 ++ + + KP NQVE HP+ Q +L FC DI+L AYS LGSH Sbjct: 176 ILNKPGLKYKPVCNQVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVL 235 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L+ P++ LA+K+ T + + Y +++G +V+ +S N RI +++ LT +E++ Sbjct: 236 LEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKA 295 Query: 309 LNDFGEKYPVRFIDEPFAAILPEF 332 ++ VR++ A P + Sbjct: 296 IDGLNRN--VRYLTLDIFAGPPNY 317 >1ZUA-X nrPDB Length = 317 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 112/309 (36%), Positives = 178/309 (57%), Gaps = 28/309 (9%) Query: 23 IYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 + L+ ++P +GLGT L + K+AVK AI AGYRHID A+ Y+ E VGEAI+ Sbjct: 4 TFVELSTKAKMPIVGLGTWK--SPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 61 Query: 83 ELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 E +++ ++KREDLFI +K+WP ++ V ++ ++LK L L Y+D+ L HWP F+ Sbjct: 62 EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 121 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 D P DD G + +L+ ++ +E++ ++ V+A+GVSNFS +E Sbjct: 122 D--------LFPKDDKGNAI-GGKATFLDAWEAMEELV---DEGLVKALGVSNFSHFQIE 169 Query: 201 RLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-------- 250 +L+ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P Sbjct: 170 KLLNKPGLKYKPVTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSL 229 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQE 308 L+ P +K++A K+ T +LI +HI++ IVIP+S+ P RI +I+ L+ +E+ Sbjct: 230 LEDPKIKEIAAKHKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMAT 289 Query: 309 LNDFGEKYP 317 + F + Sbjct: 290 ILSFNRNWR 298 >5JM5-A nrPDB Length = 332 Score = 407 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 104/324 (32%), Positives = 169/324 (52%), Gaps = 30/324 (9%) Query: 25 FSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 LN+G +P LG GT P E ++ + K AI+AG+RHID+A Y E VG AI+ Sbjct: 8 VKLNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRS 67 Query: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 + DGS+KRED+F T+K+W + V +L SLK L+YVDL L H P+ + Sbjct: 68 KIADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLK---- 123 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 G +P D++GK ++ D T++ +EK + ++IGVSNF+ LE Sbjct: 124 ----PGEELSPTDENGKVIFDI-VDLCTTWEAMEKC---KDAGLAKSIGVSNFNRRQLEM 175 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP---------N 250 ++ + + KP NQVE HP+ + +L FC DI+L AYS LGS Sbjct: 176 ILNKPGLKYKPVCNQVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVL 235 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L+ P++ LA+K+ T + + Y +++G +V+ +S N RI +++ LT ++++ Sbjct: 236 LEDPVLCALAKKHKRTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKA 295 Query: 309 LNDFGEKYPVRFIDEPFAAILPEF 332 ++ + + + A P + Sbjct: 296 IDGLDRN--LHYFNSDSFASHPNY 317 >2ALR-A nrPDB Length = 324 Score = 400 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 115/333 (34%), Positives = 177/333 (53%), Gaps = 38/333 (11%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 L+ G ++P +GLGT + + K AVK A+ GYRHID A Y EP +GEA+KE + Sbjct: 7 LHTGQKMPLIGLGTWK--SEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKEDVG 64 Query: 87 DG-SIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 G ++ RE+LF+T+K+W ++V+ +L ++L L LEY+DL L HWP FE+ +P Sbjct: 65 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP- 123 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 P + G Y + Y ET+K LE + V+A+G+SNF+ ++ ++ Sbjct: 124 -------FPKNADGTICYDST-HYKETWKALEALVAK---GLVQALGLSNFNSRQIDDIL 172 Query: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------LKIPL 255 V+P V QVE HP+L Q EL C + +TAYSPLGS L+ P+ Sbjct: 173 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPV 232 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLT--KDELQELNDFG 313 V LAEKY + +L+ + +++ I IP+S+ P RI +I+ T +E+++LN Sbjct: 233 VLALAEKYGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALN 292 Query: 314 EKYPVRFIDE---------PFAAILPEFTGNGP 337 + + R+I P A P + N P Sbjct: 293 KNW--RYIVPMLTVDGKRVPRDAGHPLYPFNDP 323 >4GAC-A nrPDB Length = 324 Score = 398 bits (1022), Expect = e-111, Method: Composition-based stats. Identities = 114/339 (33%), Positives = 179/339 (52%), Gaps = 38/339 (11%) Query: 21 TEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEA 80 T L+ G ++P +GLGT + + K A+K A+ AGYRHID A Y E +GEA Sbjct: 1 TASSVLLHTGQKMPLIGLGTWK--SEPGQVKAAIKHALSAGYRHIDCASVYGNETEIGEA 58 Query: 81 IKELLEDG-SIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFE 137 +KE + G ++ RE+LF+T+K+W ++V+ +L ++L L LEY+DL L HWP FE Sbjct: 59 LKESVGSGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFE 118 Query: 138 KIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIE 197 + +P P + G Y + Y ET+K LE + V+A+G+SNF+ Sbjct: 119 RGDNP--------FPKNADGTVRYDST-HYKETWKALEVLVAK---GLVKALGLSNFNSR 166 Query: 198 YLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN------- 250 ++ ++ V+P V QVE HP+L Q EL C + +TAYSPLGS Sbjct: 167 QIDDVLSVASVRPAVLQVECHPYLAQNELIAHCHARGLEVTAYSPLGSSDRAWRHPDEPV 226 Query: 251 -LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLT--KDELQ 307 L+ P+V LAEK+ + +L+ + +++ I IP+S+NP RI +I+ T +E++ Sbjct: 227 LLEEPVVLALAEKHGRSPAQILLRWQVQRKVICIPKSINPSRILQNIQVFDFTFSPEEMK 286 Query: 308 ELNDFGEKYPVRFIDE---------PFAAILPEFTGNGP 337 +L+ + + R+I P A P + N P Sbjct: 287 QLDALNKNW--RYIVPMITVDGKRVPRDAGHPLYPFNDP 323 >1HQT-A nrPDB Length = 326 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 114/333 (34%), Positives = 178/333 (53%), Gaps = 38/333 (11%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 L+ G ++P +GLGT + + K A+K A+ GYRHID A + E +GEA++E + Sbjct: 9 LHTGQKMPLIGLGTWK--SEPGQVKAAIKYALTVGYRHIDCAAIFGNELEIGEALQETVG 66 Query: 87 DG-SIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPK 143 G ++ RE+LF+T+K+W ++V+ +L ++L L LEY+DL L HWP FE+ +P Sbjct: 67 PGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNP- 125 Query: 144 GISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLI 203 P + G Y A Y +T+K LE + VRA+G+SNFS ++ ++ Sbjct: 126 -------FPKNADGTIRYDAT-HYKDTWKALEALVAK---GLVRALGLSNFSSRQIDDVL 174 Query: 204 KECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------LKIPL 255 V+P V QVE HP+L Q EL C + +TAYSPLGS L+ P+ Sbjct: 175 SVASVRPAVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPNEPVLLEEPV 234 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLT--KDELQELNDFG 313 V+ LAEKYN + +L+ + +++ I IP+S+ P RI +I+ T +E+++L+ Sbjct: 235 VQALAEKYNRSPAQILLRWQVQRKVICIPKSVTPSRIPQNIQVFDFTFSPEEMKQLDALN 294 Query: 314 EKYPVRFIDE---------PFAAILPEFTGNGP 337 + +RFI P A P + N P Sbjct: 295 KN--LRFIVPMLTVDGKRVPRDAGHPLYPFNDP 325 >5UXF-A nrPDB Length = 342 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 106/341 (31%), Positives = 185/341 (54%), Gaps = 34/341 (9%) Query: 9 ENI-VENMLHPKTTEIYFSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHID 66 EN+ + M + + LN+G IPALG GT P E +++ +A A+ GYRH+D Sbjct: 13 ENLYFQGM---SSKQHCVKLNDGHLIPALGFGTYKPKEVPKSKSLEAACLALDVGYRHVD 69 Query: 67 TAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEY 124 TA+AY+ E +G+AI+ + G +KREDLF+TTK+W + + V +L +SLK L L+Y Sbjct: 70 TAYAYQVEEEIGQAIQSAIAAGVVKREDLFVTTKLWCTCFRPELVKPALEKSLKKLQLDY 129 Query: 125 VDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDH 184 VDL + H+P+ + SG PV++ GK++ D+ +T+++LE+ + Sbjct: 130 VDLYIMHYPVPMK--------SGDNDFPVNEQGKSLLDT-VDFCDTWERLEEC---KDAG 177 Query: 185 RVRAIGVSNFSIEYLERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSP 242 V++IGVSNF+ LER++ + + KP NQVE H +L Q +L +C DI+L AY Sbjct: 178 LVKSIGVSNFNHRQLERILNKPGLKYKPVCNQVECHLYLNQRKLLDYCESKDIVLVAYGA 237 Query: 243 LGSHGAP---------NLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRIS 293 LG+ L P++ +A+K + + + Y I++G + + +S + Sbjct: 238 LGTQRYKEWVDQNSPVLLNDPVLCDVAKKNKRSPALIALRYLIQRGIVPLAQSFKENEMR 297 Query: 294 SSIEF--ASLTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 +++ L+ ++++ L+ + + R++ F PE+ Sbjct: 298 ENLQVFGFQLSPEDMKTLDGLNKNF--RYLPAEFLVDHPEY 336 >2HE8-A nrPDB Length = 323 Score = 394 bits (1013), Expect = e-110, Method: Composition-based stats. Identities = 114/332 (34%), Positives = 173/332 (52%), Gaps = 34/332 (10%) Query: 25 FSLNNGVRIPALGLGTANPHE-KLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 LN+G IP LG GTA P E ++ K+ K AI AG+ H D+A Y TE VGEAI+ Sbjct: 8 VILNDGNFIPVLGFGTALPLECPKSKAKELTKIAIDAGFHHFDSASVYNTEDHVGEAIRS 67 Query: 84 LLEDGSIKREDLFITTKVWPVL--WDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 + DG+++RED+F T+KVW + V SL SL+ L +YVDL L H+P+ + Sbjct: 68 KIADGTVRREDIFYTSKVWCTSLHPELVRASLERSLQKLQFDYVDLYLIHYPMALK---- 123 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 G PVD+ GK ++ D T++ +EK + ++IGVSNF+ LE Sbjct: 124 ----PGEENFPVDEHGKLIFDR-VDLCATWEAMEKC---KDAGLTKSIGVSNFNYRQLEM 175 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP---------N 250 ++ + + KP NQVE HP+L QM+L FC DI+L AY LG+ Sbjct: 176 ILNKPGLKYKPVCNQVECHPYLNQMKLLDFCKSKDIVLVAYGVLGTQRYGGWVDQNSPVL 235 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L P++ +A+KYN T + + Y +++G +V+ SL RI +++ L+ ++++ Sbjct: 236 LDEPVLGSMAKKYNRTPALIALRYQLQRGIVVLNTSLKEERIKENMQVFEFQLSSEDMKV 295 Query: 309 LNDFGEKYPVRFIDEPFAAILPEFTGNGPNLD 340 L+ +R+I P N P LD Sbjct: 296 LDGLNRN--MRYIPAAIFKGHP----NWPFLD 321 >3G1R-A nrPDB Length = 346 Score = 394 bits (1011), Expect = e-110, Method: Composition-based stats. Identities = 110/336 (32%), Positives = 180/336 (53%), Gaps = 31/336 (9%) Query: 14 NMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQA--VKAAIKAGYRHIDTAWAY 71 + + L++G IP +GLGT + + + A VK AI GYRHID A+ Y Sbjct: 19 SHMDLSAASHRIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIY 78 Query: 72 ETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLL 129 + E VGEAI+E + +G ++RED+F K+W + V +L +L+ L L+YVDL + Sbjct: 79 QNEHEVGEAIREKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYI 138 Query: 130 QHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAI 189 P+ F+ G P D++GK +Y + T++ +E + V+++ Sbjct: 139 IEVPMAFK--------PGDEIYPRDENGKWLY-HKSNLCATWEAMEAC---KDAGLVKSL 186 Query: 190 GVSNFSIEYLERLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHG 247 GVSNF+ LE ++ + + KP NQVE HP+ Q +L KFC HDI++TAYSPLG+ Sbjct: 187 GVSNFNRRQLELILNKPGLKHKPVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSR 246 Query: 248 A---------PNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF 298 P LK L+ L ++YN T +++ ++I++G +VIP+S N RI + + Sbjct: 247 NPIWVNVSSPPLLKDALLNSLGKRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQI 306 Query: 299 AS--LTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 LT++E++++ + VRF++ PE+ Sbjct: 307 FDFSLTEEEMKDIEALNKN--VRFVELLMWRDHPEY 340 >1AFS-A nrPDB Length = 323 Score = 384 bits (985), Expect = e-107, Method: Composition-based stats. Identities = 101/324 (31%), Positives = 167/324 (51%), Gaps = 30/324 (9%) Query: 25 FSLNNGVRIPALGLGTANP-HEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 +LN+G IP LG GT P E +A K AI G+RH D+A+ YE E VG+AI+ Sbjct: 8 VALNDGNFIPVLGFGTTVPEKVAKDEVIKATKIAIDNGFRHFDSAYLYEVEEEVGQAIRS 67 Query: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 +EDG++KRED+F T+K+W + V L ++LK+ L+YVDL + H+P+ + Sbjct: 68 KIEDGTVKREDIFYTSKLWSTFHRPELVRTCLEKTLKSTQLDYVDLYIIHFPMALQ---- 123 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 G + P D+ GK ++ D +T++ +EK + ++IGVSNF+ LER Sbjct: 124 ----PGDIFFPRDEHGKLLF-ETVDICDTWEAMEKC---KDAGLAKSIGVSNFNCRQLER 175 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP---------N 250 ++ + + KP NQVE H +L Q ++ +C DI+L +Y LGS Sbjct: 176 ILNKPGLKYKPVCNQVECHLYLNQSKMLDYCKSKDIILVSYCTLGSSRDKTWVDQKSPVL 235 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L P++ +A+KY T + + Y +++G + + RS N RI + L ++++ Sbjct: 236 LDDPVLCAIAKKYKQTPALVALRYQLQRGVVPLIRSFNAKRIKELTQVFEFQLASEDMKA 295 Query: 309 LNDFGEKYPVRFIDEPFAAILPEF 332 L+ + R+ + + P Sbjct: 296 LDGLNRNF--RYNNAKYFDDHPNH 317 >3H7U-A nrPDB Length = 335 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 116/318 (36%), Positives = 159/318 (50%), Gaps = 27/318 (8%) Query: 17 HPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPF 76 H +F LN G + P++GLGT AV AA+K GYRHID A Y E Sbjct: 20 HMANAITFFKLNTGAKFPSVGLGTWQAS--PGLVGDAVAAAVKIGYRHIDCAQIYGNEKE 77 Query: 77 VGEAIKELLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPL 134 +G +K+L ED +KREDLFIT+K+W D +V +LN +LK L LEYVDL L HWP Sbjct: 78 IGAVLKKLFEDRVVKREDLFITSKLWCTDHDPQDVPEALNRTLKDLQLEYVDLYLIHWPA 137 Query: 135 CFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNF 194 +K GI P D T+K +E +Y + + RAIGVSNF Sbjct: 138 RIKKG--SVGIKPENLLP------------VDIPSTWKAMEALY---DSGKARAIGVSNF 180 Query: 195 SIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN---- 250 S + L L++ RV P VNQVE HP Q +L++FC + L+AYSPLGS G Sbjct: 181 STKKLADLLELARVPPAVNQVECHPSWRQTKLQEFCKSKGVHLSAYSPLGSPGTTWLKSD 240 Query: 251 -LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFASLTKDELQEL 309 LK P++ +AEK + + + + ++ G V+P+S N RI + + + Sbjct: 241 VLKNPILNMVAEKLGKSPAQVALRWGLQMGHSVLPKSTNEGRIKENFNVFDWSIPDY-MF 299 Query: 310 NDFGEKYPVRFIDEPFAA 327 F E R + F Sbjct: 300 AKFAEIEQARLVTGSFLV 317 >1C9W-A nrPDB Length = 315 Score = 376 bits (966), Expect = e-105, Method: Composition-based stats. Identities = 110/323 (34%), Positives = 179/323 (55%), Gaps = 36/323 (11%) Query: 23 IYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 + L+ ++P +GLGT + K+AVK AI AGYRHID A+AY E VGEAI+ Sbjct: 2 TFVELSTKAKMPIVGLGTWQ--SPPGQVKEAVKVAIDAGYRHIDCAYAYYNEHEVGEAIQ 59 Query: 83 ELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 E +++ +++REDLFI +K+WP ++ + + ++L L L+Y+DL L HWP + K Sbjct: 60 EKIKEKAVRREDLFIVSKLWPTCFERKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGK 119 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 P DD G + + +L+ ++ +E++ ++ V+A+GVSNF+ +E Sbjct: 120 --------ELFPKDDQGNVL-TSKITFLDAWEVMEELV---DEGLVKALGVSNFNHFQIE 167 Query: 201 RLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-------- 250 R++ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P Sbjct: 168 RILNKPGLKHKPVTNQVECHPYLTQEKLIEYCHSKGITVTAYSPLGSPNRPWAKPEDPSL 227 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L+ P +K++A K+ T +LI +HI++ +VIP+S+ P RI + + L+ E+ Sbjct: 228 LEDPKIKEIAAKHKKTSAQVLIRFHIQRNVVVIPKSVTPARIHENFQVFDFQLSDQEMAT 287 Query: 309 LNDFGEKYPVRFIDEPFAAILPE 331 + F + A +LPE Sbjct: 288 ILGFNRNW--------RACLLPE 302 >3RX4-A nrPDB Length = 336 Score = 376 bits (965), Expect = e-105, Method: Composition-based stats. Identities = 108/306 (35%), Positives = 174/306 (56%), Gaps = 28/306 (9%) Query: 27 LNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLE 86 LNNG ++P LGLGT + +AVK AI GYRHID A Y+ E VG AI+E L Sbjct: 27 LNNGAKMPILGLGTWK--SPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLR 84 Query: 87 DGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKG 144 + +KRE+LFI +K+W ++ V + ++L L L+Y+DL L HWP F+ K Sbjct: 85 EQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK---- 140 Query: 145 ISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIK 204 P+D+SG + +D + L+T+ +E++ ++ V+AIG+SNF+ +E ++ Sbjct: 141 ----EFFPLDESGNVV-PSDTNILDTWAAMEELV---DEGLVKAIGISNFNHLQVEMILN 192 Query: 205 E--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------LKIP 254 + + KP VNQ+E HP+L Q +L ++C I++TAYSPLGS P L+ P Sbjct: 193 KPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDP 252 Query: 255 LVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELNDF 312 +K +A K+N T +LI + +++ +VIP+S+ P RI+ + + L+ ++ L + Sbjct: 253 RIKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSY 312 Query: 313 GEKYPV 318 + V Sbjct: 313 NRNWRV 318 >1DLA-A nrPDB Length = 314 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 109/309 (35%), Positives = 174/309 (56%), Gaps = 28/309 (9%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 + L G ++P LGLGT + +AVK AI GYRHID A Y+ E VG ++E Sbjct: 2 HLVLYTGAKMPILGLGTWK--SPPGKVTEAVKVAIDLGYRHIDCAHVYQNENEVGLGLQE 59 Query: 84 LLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 L+ +KREDLFI +K+W ++ V + +L+ L L+Y+DL L HWP F+ KD Sbjct: 60 KLQGQVVKREDLFIVSKLWCTDHEKNLVKGACQTTLRDLKLDYLDLYLIHWPTGFKPGKD 119 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 P P+D G + D++ET++ +E++ ++ V+AIGVSNF+ +E+ Sbjct: 120 P--------FPLDGDGNVVPDE-SDFVETWEAMEELV---DEGLVKAIGVSNFNHLQVEK 167 Query: 202 LIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN--------L 251 ++ + + KP VNQ+E HP+L Q +L ++C I++TAYSPLGS P L Sbjct: 168 ILNKPGLKYKPAVNQIEVHPYLTQEKLIEYCKSKGIVVTAYSPLGSPDRPWAKPEDPSLL 227 Query: 252 KIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQEL 309 + P +K +A KYN T +LI + +++ IVIP+S+ P RI+ + + L+ +++ L Sbjct: 228 EDPRIKAIAAKYNKTTAQVLIRFPMQRNLIVIPKSVTPERIAENFQVFDFELSPEDMNTL 287 Query: 310 NDFGEKYPV 318 + + V Sbjct: 288 LSYNRNWRV 296 >5JH1-A nrPDB Length = 309 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 116/312 (37%), Positives = 169/312 (54%), Gaps = 31/312 (9%) Query: 24 YFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 +F LN G +IP++GLG+ AV AA+KAGYRHID A Y E +G A+K+ Sbjct: 3 HFVLNTGAKIPSVGLGSWQ--SDPGVVGNAVYAAVKAGYRHIDCARVYGNEKEIGLALKK 60 Query: 84 LLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKD 141 L E+G +KRED+FIT+K+W ++V +LN+SL L LEY+DL L HWP +K + Sbjct: 61 LFEEGVVKREDMFITSKLWNDHHAPEDVPEALNDSLNDLQLEYLDLYLIHWPFRVKKGTN 120 Query: 142 PKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLER 201 + + D+ T+ +EK+Y + + RAIGVSNFS + L Sbjct: 121 TSPENFV---------------TPDFPATWGAMEKLY---DAGKARAIGVSNFSSKKLGD 162 Query: 202 LIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-----LKIPLV 256 L+ RV P V+QVE HP Q +L FC + LTAYSPLGS G LK P++ Sbjct: 163 LLAVARVPPAVDQVECHPGWQQTKLHSFCQSTGVHLTAYSPLGSPGTTWMNGNVLKEPII 222 Query: 257 KKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQELNDFGE 314 +AEK T + + ++I+ G V+P+S N RI +++ S+ D L + ++ + Sbjct: 223 ISIAEKLGKTSAQVALRWNIQMGHSVLPKSTNEERIKQNLDVYDWSIPDDLLAKFSEIKQ 282 Query: 315 KYPVR--FIDEP 324 +R FI P Sbjct: 283 ARLLRGNFIVNP 294 >1FRB-A nrPDB Length = 315 Score = 374 bits (960), Expect = e-104, Method: Composition-based stats. Identities = 114/323 (35%), Positives = 183/323 (56%), Gaps = 36/323 (11%) Query: 23 IYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 + L+ ++P +GLGT + K+AVKAAI AGYRHID A+AY E VGEAI+ Sbjct: 2 TFVELSTKAKMPIVGLGTWK--SPPNQVKEAVKAAIDAGYRHIDCAYAYCNENEVGEAIQ 59 Query: 83 ELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 E +++ +++REDLFI +K+WP +++ + + ++L L L+Y+DL L HWP + K Sbjct: 60 EKIKEKAVQREDLFIVSKLWPTCFEKKLLKEAFQKTLTDLKLDYLDLYLIHWPQGLQPGK 119 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 P DD G+ + + +LE ++ +E++ + V+A+GVSNF+ +E Sbjct: 120 --------ELFPKDDQGRIL-TSKTTFLEAWEGMEELV---DQGLVKALGVSNFNHFQIE 167 Query: 201 RLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP--------N 250 RL+ + + KP NQVE HP+L Q +L ++C I +TAYSPLGS P Sbjct: 168 RLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGISVTAYSPLGSPDRPSAKPEDPSL 227 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L+ P +K++A K+ T +LI +HI++ +VIP+S+ P RI +I+ L+ +E+ Sbjct: 228 LEDPKIKEIAAKHEKTSAQVLIRFHIQRNVVVIPKSVTPSRIQENIQVFDFQLSDEEMAT 287 Query: 309 LNDFGEKYPVRFIDEPFAAILPE 331 + F + A +LPE Sbjct: 288 ILSFNRNW--------RACLLPE 302 >4HBK-A nrPDB Length = 344 Score = 367 bits (942), Expect = e-102, Method: Composition-based stats. Identities = 100/339 (29%), Positives = 176/339 (51%), Gaps = 31/339 (9%) Query: 3 SSVASTENIVENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGY 62 +S+ + + + P +NNG IP +GLGT + E AVK A++ GY Sbjct: 22 ASMTGGQQMGRGSMEP------LKMNNGRSIPVIGLGTW--NSPPGEVGAAVKKALEIGY 73 Query: 63 RHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKAL 120 RH+D A+ Y E +GEA++ L +KRED+FIT+K+W + + V ++ E+LK L Sbjct: 74 RHLDCAYVYRNEAEIGEALENALNSLRLKREDIFITSKLWNTFFRPEHVRKACEETLKNL 133 Query: 121 GLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLD 180 L Y+DL L HWP+ + D P D +G+ + + +T+K++EK+ Sbjct: 134 RLNYLDLYLIHWPVPLKHGGD--------LFPTDSNGQLCLD-NVPHEDTWKEMEKLV-- 182 Query: 181 PNDHRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAY 240 ++ V++IG+SNF+ ++ +++ CR+KP Q+E H + P ++L ++ + +TAY Sbjct: 183 -DEGLVKSIGLSNFNKRQIQNILEHCRIKPANLQIEIHANFPNIKLVEYAQSVGLTVTAY 241 Query: 241 SPLGSHGA-----PNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSS 295 +PLGS L P V ++A ++ T +L+ Y +++ IV+P+S+ RI + Sbjct: 242 APLGSPAHSPGKVNLLTKPCVLEIAHRHKKTPAQVLLRYLLQRKLIVVPKSVTFKRIEEN 301 Query: 296 IEF--ASLTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 + L+ +E+ ELN R + E+ Sbjct: 302 FQVFDFQLSNEEMHELNTESLN--ERQFTLLQMSGHQEY 338 >3O3R-A nrPDB Length = 316 Score = 363 bits (931), Expect = e-101, Method: Composition-based stats. Identities = 101/309 (32%), Positives = 171/309 (55%), Gaps = 28/309 (9%) Query: 23 IYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIK 82 + L ++P +GLGT + K+AVKAAI AGYRH D A+ Y+ E VGEAI+ Sbjct: 3 TFVKLRTKAKMPLVGLGTWK--SPPGQVKEAVKAAIDAGYRHFDCAYVYQNESEVGEAIQ 60 Query: 83 ELLEDGSIKREDLFITTKVWPVLWDE--VDRSLNESLKALGLEYVDLLLQHWPLCFEKIK 140 E +++ +++REDLFI +K+W +++ + + ++L L L+Y+DL L HWP + K Sbjct: 61 EKIKEKAVRREDLFIVSKLWSTFFEKSLMKEAFQKTLSDLKLDYLDLYLIHWPQGLQAGK 120 Query: 141 DPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLE 200 P D GK + + +L+ ++ +E++ + V+A+GVSNF+ +E Sbjct: 121 --------EFLPKDSQGKVLM-SKSTFLDAWEGMEELV---DQGLVKALGVSNFNHFQIE 168 Query: 201 RLIKE--CRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN-------- 250 RL+ + + KP NQVE HP+L Q +L ++C I + AYSPLGS P Sbjct: 169 RLLNKPGLKHKPVTNQVECHPYLTQEKLIQYCHSKGIAVIAYSPLGSPDRPYAKPEDPVV 228 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 L+IP +K++A K+ T +LI +H+++ VIP+S+ I +I+ L+++++ Sbjct: 229 LEIPKIKEIAAKHKKTIAQVLIRFHVQRNVAVIPKSVTLSHIKENIQVFDFQLSEEDMAA 288 Query: 309 LNDFGEKYP 317 + + Sbjct: 289 ILSLNRNWR 297 >3H7R-A nrPDB Length = 331 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 104/312 (33%), Positives = 162/312 (51%), Gaps = 32/312 (10%) Query: 17 HPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPF 76 H +F LN G ++P +GLGT A A++ AIK GYRHID A Y E Sbjct: 20 HMAAPIRFFELNTGAKLPCVGLGTY------AMVATAIEQAIKIGYRHIDCASIYGNEKE 73 Query: 77 VGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPL 134 +G +K+L+ DG +KRE+LFIT+K+W ++V ++L ++L+ L ++YVDL L HWP Sbjct: 74 IGGVLKKLIGDGFVKREELFITSKLWSNDHLPEDVPKALEKTLQDLQIDYVDLYLIHWPA 133 Query: 135 CFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNF 194 +K L+ TP D T+K +E +Y + + RAIGVSNF Sbjct: 134 SLKK-------ESLMPTPE-------MLTKPDITSTWKAMEALY---DSGKARAIGVSNF 176 Query: 195 SIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPN---- 250 S + L L+ RV P VNQVE HP Q L + C + L+ YSPLGS Sbjct: 177 SSKKLTDLLNVARVTPAVNQVECHPVWQQQGLHELCKSKGVHLSGYSPLGSQSKGEVRLK 236 Query: 251 -LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQ 307 L+ P+V ++AEK T + + + ++ G V+P+S + R+ +++ + +D Sbjct: 237 VLQNPIVTEVAEKLGKTTAQVALRWGLQTGHSVLPKSSSGARLKENLDVFDWSIPEDLFT 296 Query: 308 ELNDFGEKYPVR 319 + ++ ++ R Sbjct: 297 KFSNIPQEKFCR 308 >5Z6T-A nrPDB Length = 343 Score = 359 bits (922), Expect = e-100, Method: Composition-based stats. Identities = 101/338 (29%), Positives = 160/338 (47%), Gaps = 33/338 (9%) Query: 18 PKTTEIYF-------SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWA 70 P T IYF LN+G +PA+G G + + AIK GYR D A Sbjct: 15 PTTENIYFQGHMPSIKLNSGYDMPAVGFGCWKVDVD--TCSEQIYRAIKTGYRLFDGAED 72 Query: 71 YETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLL 128 Y E VG +K+ +++G +KREDLF+T+K+W D V+++LN +L L ++YVDL Sbjct: 73 YANEKLVGAGVKKAIDEGIVKREDLFLTSKLWNNYHHPDNVEKALNRTLSDLQVDYVDLF 132 Query: 129 LQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRA 188 L H+P+ F+ + + G D LET+K LEK+ ++R+ Sbjct: 133 LIHFPVTFKFVPLEEKYPPGFYC---GKGDNFDYEDVPILETWKALEKLV---KAGKIRS 186 Query: 189 IGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHG- 247 IGVSNF L L++ +KP+V QVE HP+L Q L +F I +TAYS G Sbjct: 187 IGVSNFPGALLLDLLRGATIKPSVLQVEHHPYLQQPRLIEFAQSRGIAVTAYSSFGPQSF 246 Query: 248 -----------APNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSI 296 +P + +K +A K+ + +L+ + ++G +IP+S R+ + Sbjct: 247 VELNQGRALNTSPLFENETIKAIAAKHGKSPAQVLLRWSSQRGIAIIPKSNTVPRLLENK 306 Query: 297 EF--ASLTKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 + L + + ++ +RF D +P F Sbjct: 307 DVNSFDLDEQDFADIAKLDIN--LRFNDPWDWDKIPIF 342 >4GIE-A nrPDB Length = 290 Score = 353 bits (907), Expect = 4e-98, Method: Composition-based stats. Identities = 110/307 (35%), Positives = 169/307 (55%), Gaps = 42/307 (13%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 +L+N VR+P LGLG + AET AV+ AI+AGYRHIDTA+ Y E VG+ I+E Sbjct: 16 VTLHNSVRMPQLGLGVWRAQDG-AETANAVRWAIEAGYRHIDTAYIYSNERGVGQGIRE- 73 Query: 85 LEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + RE++++TTKVW +++ + S + LGLEY+DL L HWP Sbjct: 74 ---SGVPREEVWVTTKVWNSDQGYEKTLAAFERSRELLGLEYIDLYLIHWP--------- 121 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 +++T+K LEK+Y + +VRAIGVSNF +L L Sbjct: 122 --------------------GKKKFVDTWKALEKLY---EEKKVRAIGVSNFEPHHLTEL 158 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGA-PNLKIPLVKKLAE 261 K C+++P VNQVE HP Q LR+FC H+I +TA+SPLGS LK ++ ++A+ Sbjct: 159 FKSCKIRPMVNQVELHPLFQQRTLREFCKQHNIAITAWSPLGSGEEAGILKNHVLGEIAK 218 Query: 262 KYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELNDFGEKYPVR 319 K+N + ++I + I+ G + IP+S N RI + LT++E++++++ E + Sbjct: 219 KHNKSPAQVVIRWDIQHGIVTIPKSTNKGRIQENFNVWDFKLTEEEMRQIDELNEDKRIG 278 Query: 320 FIDEPFA 326 + F Sbjct: 279 ADPDNFF 285 >5ZCM-A nrPDB Length = 341 Score = 353 bits (906), Expect = 5e-98, Method: Composition-based stats. Identities = 89/312 (28%), Positives = 150/312 (48%), Gaps = 26/312 (8%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 LN+G +P +G G A V AIK GYR D A Y +GE I Sbjct: 24 IKLNSGYEMPLVGFGCWKVDN--ATCADTVYNAIKVGYRLFDAAMDYGNCKEIGEGINRA 81 Query: 85 LEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 L++G + R++LFIT+K+W D V+ +L + L + L+Y+DL L H+P+ F+ + Sbjct: 82 LDEGLVARDELFITSKLWNSYHDPKNVELALKKVLSDMKLDYIDLFLIHFPIAFKFVPFE 141 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 + G + D LET+K +EK+ + ++IG+SNFS + L Sbjct: 142 EKYPPAFYC---GDGDNFHYEDVPLLETWKAMEKL---TKGGKAKSIGISNFSAALIYDL 195 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHG------------APN 250 ++ +KP V Q+E HP+L Q L ++ I +TAYS G Sbjct: 196 LRGAEIKPAVLQIEHHPYLQQPRLIEYVQSQGIAITAYSSFGPQSFLELKHSKALDTPTL 255 Query: 251 LKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQE 308 + + +A+KY T +L+ + ++ +IP+S NP R+ ++E +L+K++ E Sbjct: 256 FEHKTITSIADKYKKTPAQVLLRWASQRDIAIIPKSNNPDRLLQNLEVNDFNLSKEDFDE 315 Query: 309 LNDFGEKYPVRF 320 ++ + +RF Sbjct: 316 ISKLDQD--LRF 325 >1K8C-A nrPDB Length = 322 Score = 352 bits (904), Expect = 1e-97, Method: Composition-based stats. Identities = 100/331 (30%), Positives = 160/331 (48%), Gaps = 26/331 (7%) Query: 18 PKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFV 77 + L++G +P++G G A + V AIKAGYR D A Y E V Sbjct: 1 MSASIPDIKLSSGHLMPSIGFGCWKLAN--ATAGEQVYQAIKAGYRLFDGAEDYGNEKEV 58 Query: 78 GEAIKELLEDGSIKREDLFITTKVWPVLWD--EVDRSLNESLKALGLEYVDLLLQHWPLC 135 G+ +K +++G +KRE++F+T+K+W D V+ +LN++L L ++YVDL L H+P+ Sbjct: 59 GDGVKRAIDEGLVKREEIFLTSKLWNNYHDPKNVETALNKTLADLKVDYVDLFLIHFPIA 118 Query: 136 FEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFS 195 F+ + + G D LET+K LEK+ ++++IGVSNF Sbjct: 119 FKFVPIEEKYPPGFYC---GDGNNFVYEDVPILETWKALEKLVA---AGKIKSIGVSNFP 172 Query: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHG-------- 247 L L++ +KP V QVE HP+L Q +L +F + +TAYS G Sbjct: 173 GALLLDLLRGATIKPAVLQVEHHPYLQQPKLIEFAQKAGVTITAYSSFGPQSFVEMNQGR 232 Query: 248 ----APNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSS--IEFASL 301 +K +A KYN T ++L+ + ++G VIP+S P R+ + L Sbjct: 233 ALNTPTLFAHDTIKAIAAKYNKTPAEVLLRWAAQRGIAVIPKSNLPERLVQNRSFNTFDL 292 Query: 302 TKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 TK++ +E+ +RF D +P F Sbjct: 293 TKEDFEEIAKLD--IGLRFNDPWDWDNIPIF 321 >3WCZ-A nrPDB Length = 308 Score = 351 bits (900), Expect = 3e-97, Method: Composition-based stats. Identities = 114/331 (34%), Positives = 164/331 (49%), Gaps = 41/331 (12%) Query: 18 PKTTEIYFSLNNGVRIPALGLGT----ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYET 73 LN+G IP + LGT A + + E +QAV AI+AGYRHIDTA Y+ Sbjct: 1 MAVQAPCIQLNDGNTIPIVALGTGRGTAKESDSIDEVRQAVYWAIEAGYRHIDTAAVYQD 60 Query: 74 EPFVGEAIKELLEDGSIKREDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQH 131 E VG+ I E + +G + RE+LF+TTK+W D+V +L ESLK LGL+Y+DL L H Sbjct: 61 EEQVGQGIAEAIANGLVTREELFVTTKLWNDKHARDQVVPALQESLKKLGLDYIDLYLIH 120 Query: 132 WPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGV 191 +P+ + P I DYLET++ ++ R+IGV Sbjct: 121 FPIATKPDDSPDNI--------------------DYLETWQGMQDARQL---GLARSIGV 157 Query: 192 SNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLG---SHGA 248 SNF+ + RL+ ++P +NQ+E +P Q L C I + AYSP G S G Sbjct: 158 SNFNATQITRLVSNSYIRPVINQIEVNPTNTQEPLVAHCQSLGIAVMAYSPFGFVVSRGQ 217 Query: 249 -----PNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASL 301 P P + LA KY + +L+ Y I +G I IP+S N RI+ +I+ L Sbjct: 218 TGAPPPRSDDPTLTALANKYRKSVGQILLRYLIDRGLIPIPKSTNKQRIAQNIDLFDFQL 277 Query: 302 TKDELQELNDFGEKYPVRFIDEPFAAILPEF 332 T +E+ +N F + + R ID P + Sbjct: 278 TFEEVAAINQFNKNH--RVIDISDWKDYPNY 306 >2BGQ-A nrPDB Length = 344 Score = 344 bits (882), Expect = 4e-95, Method: Composition-based stats. Identities = 99/303 (32%), Positives = 158/303 (52%), Gaps = 25/303 (8%) Query: 21 TEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAI-KAGYRHIDTAWAYETEPFVGE 79 + +F L +G +PA+GLGT A + V+ AI +AGYRH+DTA Y E VG+ Sbjct: 36 EQDHFVLKSGHAMPAVGLGTWRAGSDTAHS---VRTAITEAGYRHVDTAAEYGVEKEVGK 92 Query: 80 AIKELLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFE 137 +K +E G I R+DLF+T+K+W + V +L +LK L L+Y+DL HWP + Sbjct: 93 GLKAAMEAG-IDRKDLFVTSKIWCTNLAPERVRPALENTLKDLQLDYIDLYHIHWPFRLK 151 Query: 138 KIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIE 197 +G V + D +K++E + D V+ IGV N+++ Sbjct: 152 DGAHMPPEAGEVL-------------EFDMEGVWKEMENLV---KDGLVKDIGVCNYTVT 195 Query: 198 YLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVK 257 L RL++ ++ P V Q+E HP ++ + C H I +TAYSPLGS P+V+ Sbjct: 196 KLNRLLRSAKIPPAVCQMEMHPGWKNDKIFEACKKHGIHITAYSPLGSSEKNLAHDPVVE 255 Query: 258 KLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFA--SLTKDELQELNDFGEK 315 K+A K N T +LI + +++GT VIP+S RI +I+ + +++ + L ++ Sbjct: 256 KVANKLNKTPGQVLIKWALQRGTSVIPKSSKDERIKENIQVFGWEIPEEDFKVLCSIKDE 315 Query: 316 YPV 318 V Sbjct: 316 KRV 318 >1VBJ-A nrPDB Length = 281 Score = 343 bits (879), Expect = 9e-95, Method: Composition-based stats. Identities = 105/306 (34%), Positives = 153/306 (50%), Gaps = 43/306 (14%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 L+NGV +P LG G + E + A AIK+GYRHIDTA Y+ E G AI Sbjct: 12 LKLSNGVMMPVLGFGMWKLQDG-NEAETATMWAIKSGYRHIDTAAIYKNEESAGRAIASC 70 Query: 85 LEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + RE+LF+TTK+W ++ + +S+K LGLEYVDL L HWP Sbjct: 71 ----GVPREELFVTTKLWNSDQGYESTLSAFEKSIKKLGLEYVDLYLIHWP--------- 117 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 +++T+K EK+Y D +VRAIGVSNF ++E L Sbjct: 118 --------------------GKDKFIDTWKAFEKLYADK---KVRAIGVSNFHEHHIEEL 154 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEK 262 +K C+V P VNQ+E HP L Q L ++C +I +TA+SPLG ++ +K + K Sbjct: 155 LKHCKVAPMVNQIELHPLLNQKALCEYCKSKNIAVTAWSPLGQGH--LVEDARLKAIGGK 212 Query: 263 YNVTGNDLLISYHIRQGTIVIPRSLNPVRISS--SIEFASLTKDELQELNDFGEKYPVRF 320 Y T +++ + I+ G I IP+S N RI +I LT +++Q ++ + Sbjct: 213 YGKTAAQVMLRWEIQAGVITIPKSGNEARIKENGNIFDFELTAEDIQVIDGMNAGHRYGP 272 Query: 321 IDEPFA 326 E F Sbjct: 273 DPEVFM 278 >4F40-A nrPDB Length = 288 Score = 340 bits (872), Expect = 6e-94, Method: Composition-based stats. Identities = 97/301 (32%), Positives = 152/301 (50%), Gaps = 35/301 (11%) Query: 22 EIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAI 81 + +L+NGV++P GLG T+ AVK A+ AGYRHIDTA Y+ E VG + Sbjct: 10 KAMVTLSNGVKMPQFGLGVWQSPAGEV-TENAVKWALCAGYRHIDTAAIYKNEESVGAGL 68 Query: 82 KELLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKI 139 + + RED+FITTK+W ++ + ES + LG++Y+DL L HWP Sbjct: 69 RA----SGVPREDVFITTKLWNTEQGYESTLAAFEESRQKLGVDYIDLYLIHWPRG---- 120 Query: 140 KDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYL 199 + YL++++ E++Y + +VRAIGVSNF I +L Sbjct: 121 -----------------KDILSKEGKKYLDSWRAFEQLY---KEKKVRAIGVSNFHIHHL 160 Query: 200 ERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKL 259 E ++ C V P VNQVE HP Q +LR FC I + A+SPLG L P++ + Sbjct: 161 EDVLAMCTVTPMVNQVELHPLNNQADLRAFCDAKQIKVEAWSPLGQGK--LLSNPILSAI 218 Query: 260 AEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELNDFGEKYP 317 KYN T +++ ++I++ I IP+S++ RI + + L +++ ++ Sbjct: 219 GAKYNKTAAQVILRWNIQKNLITIPKSVHRERIEENADIFDFELGAEDVMSIDALNTNSR 278 Query: 318 V 318 Sbjct: 279 Y 279 >1VP5-A nrPDB Length = 298 Score = 339 bits (870), Expect = 1e-93, Method: Composition-based stats. Identities = 96/314 (30%), Positives = 153/314 (48%), Gaps = 44/314 (14%) Query: 15 MLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETE 74 M PK +LNNGV +P LG G +T++ V AIK GYR IDTA +Y E Sbjct: 13 MQVPK-----VTLNNGVEMPILGYGVFQI--PPEKTEECVYEAIKVGYRLIDTAASYMNE 65 Query: 75 PFVGEAIKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHW 132 VG AIK +++G ++RE+LF+TTK+W V ++ ++ +SLK L LEY+DL L H Sbjct: 66 EGVGRAIKRAIDEGIVRREELFVTTKLWVSDVGYESTKKAFEKSLKKLQLEYIDLYLIHQ 125 Query: 133 PLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVS 192 P GD +K +E++Y D VRAIGVS Sbjct: 126 PF------------------------------GDVHCAWKAMEEMY---KDGLVRAIGVS 152 Query: 193 NFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLK 252 NF + L L+ + P VNQ+E HP + E +F ++I A+ P + Sbjct: 153 NFYPDRLMDLMVHHEIVPAVNQIEIHPFYQRQEEIEFMRNYNIQPEAWGPFAEGRKNIFQ 212 Query: 253 IPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELN 310 +++ +AEKY T +++ + ++G + IP+++ R+ +I LT+++++++ Sbjct: 213 NGVLRSIAEKYGKTVAQVILRWLTQKGIVAIPKTVRRERMKENISIFDFELTQEDMEKIA 272 Query: 311 DFGEKYPVRFIDEP 324 E F Sbjct: 273 TLDEGQSAFFSHRD 286 >3KRB-A nrPDB Length = 334 Score = 338 bits (868), Expect = 2e-93, Method: Composition-based stats. Identities = 92/320 (28%), Positives = 158/320 (49%), Gaps = 33/320 (10%) Query: 34 PALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLED--GSIK 91 P LG GT + + AV+ A+ GYRHID A+ Y+ E +G A ++ +D IK Sbjct: 26 PRLGFGTWQAPPEA--VQTAVETALMTGYRHIDCAYVYQNEEAIGRAFGKIFKDASSGIK 83 Query: 92 REDLFITTKVWPVLW--DEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLV 149 RED++IT+K+W + V +++ L ++Y+DL L HWPL F + Sbjct: 84 REDVWITSKLWNYNHRPELVREQCKKTMSDLQVDYLDLFLVHWPLAFVRNDVGD------ 137 Query: 150 KTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVK 209 P D G+ M +T++ +E++ + V+ IGVSN+++ L L+ ++K Sbjct: 138 LFPKDAEGRAML-EKVPLADTWRAMEQLV---EEGLVKHIGVSNYTVPLLADLLNYAKIK 193 Query: 210 PTVNQVETHPHLPQMELRKFCFMHDILLTAYSPL-----------GSHGAPNLKIPLVKK 258 P VNQ+E HP P KFC + I +TAYSP+ G+ L+ +K Sbjct: 194 PLVNQIEIHPWHPNDATVKFCLDNGIGVTAYSPMGGSYADPRDPSGTQKNVILECKTLKA 253 Query: 259 LAEKYNVTGNDLLISYHIRQGT----IVIPRSLNPVRISSSIEFA--SLTKDELQELNDF 312 +A+ + + + +++H+++ VIP+S P RI ++ + L+ D++ +N+ Sbjct: 254 IADAKGTSPHCVALAWHVKKWNTSMYSVIPKSQTPARIEANFKCTEVQLSDDDMDAINNI 313 Query: 313 GEKYPVRFIDEPFAAILPEF 332 +RF D +P F Sbjct: 314 HLNKRIRFCDPAIFWKVPLF 333 >1MZR-A nrPDB Length = 296 Score = 334 bits (857), Expect = 3e-92, Method: Composition-based stats. Identities = 98/296 (33%), Positives = 151/296 (51%), Gaps = 38/296 (12%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 L +G +P LGLG + E A++ A++ GYR IDTA AY+ E VG+A+K Sbjct: 28 IKLQDGNVMPQLGLGVWQASNE--EVITAIQKALEVGYRSIDTAAAYKNEEGVGKALKNA 85 Query: 85 LEDGSIKREDLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKG 144 S+ RE+LFITTK+W +L +SLK L L+Y+DL L HWP+ Sbjct: 86 ----SVNREELFITTKLWNDDHKRPREALLDSLKKLQLDYIDLYLMHWPV---------- 131 Query: 145 ISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIK 204 A Y+E +K + ++ + +++IGV NF I +L+RLI Sbjct: 132 -----------------PAIDHYVEAWKGMIEL---QKEGLIKSIGVCNFQIHHLQRLID 171 Query: 205 ECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEKYN 264 E V P +NQ+E HP + Q +L + H I ++SPL G +++ LA+KY Sbjct: 172 ETGVTPVINQIELHPLMQQRQLHAWNATHKIQTESWSPLAQGGKGVFDQKVIRDLADKYG 231 Query: 265 VTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELNDFGEKYPV 318 T ++I +H+ G +VIP+S+ P RI+ + + L KDEL E+ + + Sbjct: 232 KTPAQIVIRWHLDSGLVVIPKSVTPSRIAENFDVWDFRLDKDELGEIAKLDQGKRL 287 >1QWK-A nrPDB Length = 317 Score = 330 bits (847), Expect = 5e-91, Method: Composition-based stats. Identities = 112/335 (33%), Positives = 166/335 (49%), Gaps = 47/335 (14%) Query: 18 PKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFV 77 + L+NGV +P +GLGT AE AVK A+KAGYR IDTA Y+ E + Sbjct: 1 MSSATASIKLSNGVEMPVIGLGTWQ--SSPAEVITAVKTAVKAGYRLIDTASVYQNEEAI 58 Query: 78 GEAIKELLEDGSIKREDLFITTKVWPV--LWDEVDRSLNESLKALGLEYVDLLLQHWPLC 135 G AIKELLE+G +KRE+LFITTK W +++ L ESLK L LEYVDL L H P Sbjct: 59 GTAIKELLEEGVVKREELFITTKAWTHELAPGKLEGGLRESLKKLQLEYVDLYLAHMPAA 118 Query: 136 FEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFS 195 F +S + +PV+ + ++Q + +Y +A+GVSN++ Sbjct: 119 FN-----DDMSEHIASPVE--------------DVWRQFDAVY---KAGLAKAVGVSNWN 156 Query: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPL 255 + + R + +QVE H + PQ + FC H+I +T+Y+ LGS G N +P Sbjct: 157 NDQISRALALGLTPVHNSQVELHLYFPQHDHVDFCKKHNISVTSYATLGSPGRVNFTLPT 216 Query: 256 -----------------VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF 298 V LAEK + T +L+ Y + +G ++P+S+ RI + E Sbjct: 217 GQKLDWAPAPSDLQDQNVLALAEKTHKTPAQVLLRYALDRGCAILPKSIQENRIKENFEV 276 Query: 299 AS--LTKDELQELNDFGEKYPVRFIDEPFAAILPE 331 LT++++ +L + K R + F PE Sbjct: 277 FDFSLTEEDIAKLEE--SKNSQRLFLQDFMTGHPE 309 >4MHB-A nrPDB Length = 297 Score = 320 bits (819), Expect = 8e-88, Method: Composition-based stats. Identities = 81/320 (25%), Positives = 136/320 (42%), Gaps = 42/320 (13%) Query: 12 VENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAY 71 LNNG+ +P LG G AE ++AV AI+ GYR IDTA +Y Sbjct: 5 FPTQQLKDNVMQTVKLNNGIAMPLLGFGVFQM-TNTAECERAVIDAIETGYRLIDTAASY 63 Query: 72 ETEPFVGEAIKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLL 129 + E VG A+K I R++LFITTK+W ++ SL L L+YVDL L Sbjct: 64 QNETQVGNALKL----SGIARDELFITTKLWLQDTYYEGAKAQFERSLNRLQLDYVDLYL 119 Query: 130 QHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAI 189 H P GD ++ +E+++ ++RAI Sbjct: 120 IHQPY------------------------------GDVHGAWRAMEELH---QAGKIRAI 146 Query: 190 GVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAP 249 GVSNF + L L+ ++ P VNQ+E +P Q+ + I A++P Sbjct: 147 GVSNFHPDRLADLMAFNKIIPAVNQIEVNPFNQQLHAVPWMQSRGIQPEAWAPFAEGRNG 206 Query: 250 NLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQ 307 + P++ + EKY + +++ + ++G + + +S+ R+ +I L+ +++ Sbjct: 207 LFQNPVLTAIGEKYGKSVGQVVLRWIFQRGIVSLAKSVRKGRMEENINILDFELSAEDML 266 Query: 308 ELNDFGEKYPVRFIDEPFAA 327 ++ F A Sbjct: 267 QIAALDTATSAFFSHRDPAM 286 >3D3F-A nrPDB Length = 275 Score = 313 bits (802), Expect = 6e-86, Method: Composition-based stats. Identities = 109/331 (32%), Positives = 166/331 (50%), Gaps = 60/331 (18%) Query: 18 PKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFV 77 P + + L+NGV +P GLG E E ++VKAAIK GYR IDTA Y+ E V Sbjct: 1 PTSLKDTVKLHNGVEMPWFGLGVFKV-ENGNEATESVKAAIKNGYRSIDTAAIYKNEEGV 59 Query: 78 GEAIKELLEDGSIKREDLFITTKVWP--VLWDEVDRSLNESLKALGLEYVDLLLQHWPLC 135 G IKE + RE+LFIT+KVW ++ + +SL+ L L+Y+DL L HWP Sbjct: 60 GIGIKE----SGVAREELFITSKVWNEDQGYETTLAAFEKSLERLQLDYLDLYLIHWP-- 113 Query: 136 FEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFS 195 Y +T++ LEK+Y D ++RAIGVSNF Sbjct: 114 ---------------------------GKDKYKDTWRALEKLY---KDGKIRAIGVSNFQ 143 Query: 196 IEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPL 255 + +LE L+K+ +KP VNQVE HP L Q ELR +C I L A+SPL L + Sbjct: 144 VHHLEELLKDAEIKPMVNQVEFHPRLTQKELRDYCKGQGIQLEAWSPLMQGQ--LLDNEV 201 Query: 256 VKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELNDFG 313 + ++AEK+N + +++ + ++ G + IP+S+ RI + + L+++++ +++ Sbjct: 202 LTQIAEKHNKSVAQVILRWDLQHGVVTIPKSIKEHRIIENADIFDFELSQEDMDKIDALN 261 Query: 314 EKYPVRFIDEPFAAILPEFTGNGPNLDNLKY 344 + V GPN D L + Sbjct: 262 KDERV-----------------GPNPDELLF 275 >1A80-A nrPDB Length = 277 Score = 299 bits (765), Expect = 1e-81, Method: Composition-based stats. Identities = 87/293 (29%), Positives = 138/293 (47%), Gaps = 40/293 (13%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 LN+G IP LG G A+T++AV+ A++ GYRHIDTA Y E V Sbjct: 5 IVLNDGNSIPQLGYGVFK--VPPADTQRAVEEALEVGYRHIDTAAIYGNEEGV----GAA 58 Query: 85 LEDGSIKREDLFITTKVWPVLWDEVDRS--LNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + I R+DLFITTK+W D + + + ESL L L+ VDL L HWP Sbjct: 59 IAASGIARDDLFITTKLWNDRHDGDEPAAAIAESLAKLALDQVDLYLVHWP--------- 109 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 TP D+ Y+ ++++ ++ R+IGVSN + +LER+ Sbjct: 110 --------TPAADN----------YVHAWEKMIELRA---AGLTRSIGVSNHLVPHLERI 148 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEK 262 + V P VNQ+E HP Q E+ + HD+ + ++ PLG V A Sbjct: 149 VAATGVVPAVNQIELHPAYQQREITDWAAAHDVKIESWGPLGQGKYDLFGAEPVTAAAAA 208 Query: 263 YNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEF--ASLTKDELQELNDFG 313 + T ++ +H+++G +V P+S+ R+ +++ LT E+ ++ Sbjct: 209 HGKTPAQAVLRWHLQKGFVVFPKSVRRERLEENLDVFDFDLTDTEIAAIDAMD 261 >4OTK-A nrPDB Length = 318 Score = 296 bits (759), Expect = 6e-81, Method: Composition-based stats. Identities = 97/299 (32%), Positives = 141/299 (47%), Gaps = 42/299 (14%) Query: 25 FSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKEL 84 +LN+ +P LGLG A + ET++AV AA++ G R IDTA+AY E VG AI Sbjct: 49 ITLNDEHTMPVLGLGVAELSDD--ETERAVSAALEIGCRLIDTAYAYGNEAAVGRAI--- 103 Query: 85 LEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 + RE+LF+TTK+ + + SL LGL+YVDL L HWP Sbjct: 104 -AASGVAREELFVTTKLATPDQGFTRSQEACRASLDRLGLDYVDLYLIHWPA-------- 154 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 G Y++ + + + + R+IGVSNF+ E +E L Sbjct: 155 -------------------PPVGKYVDAWGGMIQ---SRGEGHARSIGVSNFTAENIENL 192 Query: 203 IKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGSHGAPNLKIPLVKKLAEK 262 I V P VNQ+E HP L Q ELRK H ++ +Y PL L P V +A + Sbjct: 193 IDLTFVTPAVNQIELHPLLNQDELRKANAQHTVVTQSYCPLALGR--LLDNPTVTSIASE 250 Query: 263 YNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS--LTKDELQELNDFGEKYPVR 319 Y T +L+ ++++ G V+ RS P RI+S+ + L + + L + VR Sbjct: 251 YVKTPAQVLLRWNLQLGNAVVVRSARPERIASNFDVFDFELAAEHMDALGGLNDGTRVR 309 >3UP8-A nrPDB Length = 298 Score = 286 bits (731), Expect = 1e-77, Method: Composition-based stats. Identities = 88/314 (28%), Positives = 144/314 (45%), Gaps = 52/314 (16%) Query: 7 STENI-VENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHI 65 TEN+ ++M+H + +NG IPALG GT AE + + A+K G+RH+ Sbjct: 14 GTENLYFQSMMHAVS-------SNGANIPALGFGTFRMSG--AEVLRILPQALKLGFRHV 64 Query: 66 DTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVW--PVLWDEVDRSLNESLKALGLE 123 DTA Y E VGEAI++ I R D+F+TTKVW D S++ESL+ L + Sbjct: 65 DTAQIYGNEAEVGEAIQK----SGIPRADVFLTTKVWVDNYRHDAFIASVDESLRKLRTD 120 Query: 124 YVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPND 183 +VDLLL HWP +D E L ++ N Sbjct: 121 HVDLLLLHWP----------------------------GSDVPMAERIGALNEV---RNA 149 Query: 184 HRVRAIGVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPL 243 +VR IG+SNF+ +E + NQVE HP+L Q ++ + + LT+Y + Sbjct: 150 GKVRHIGISNFNTTQMEEAARLSDAPIATNQVEYHPYLDQTKVLQTARRLGMSLTSYYAM 209 Query: 244 GSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHI-RQGTIVIPRSLNPVRISSSIEFAS-- 300 + P PL+ ++ ++ T + + + + +Q IV+ ++ R+ + Sbjct: 210 ANGKVP--ADPLLTEIGGRHGKTAAQVALRWLVQQQDVIVLSKTATEARLKENFAIFDFA 267 Query: 301 LTKDELQELNDFGE 314 LT++E+ + + Sbjct: 268 LTREEMAAVRELAR 281 >4H8N-A nrPDB Length = 310 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 104/341 (30%), Positives = 154/341 (45%), Gaps = 61/341 (17%) Query: 10 NIVENMLHPKTTEIYFSLNNGVRIP-ALGLGTANPHEKLAETKQAVKA--------AIKA 60 ++ ++ L PKT F +G I ALG GT K A+T V +K Sbjct: 3 HMTQSNLLPKT----FRTKSGKEISIALGTGT---KWKQAQTINDVSTELVDNILLGLKL 55 Query: 61 GYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPV------LWDEVDRSLN 114 G+RHIDTA AY T+ VGEA+K + RED+++TTK P S++ Sbjct: 56 GFRHIDTAEAYNTQKEVGEALKRT----DVPREDIWVTTKYSPGWGSIKAYSKSPSDSID 111 Query: 115 ESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQL 174 ++L LG++YVDL L H P T G T+ ++ Sbjct: 112 KALAQLGVDYVDLFLIHSPF---------------FTTEQTHGYTLEQ-------AWEA- 148 Query: 175 EKIYLDPNDHRVRAIGVSNFSIEYLERLIKEC---RVKPTVNQVETHPHLPQME--LRKF 229 + +VR IG+SN +I +LE+L P VNQ+E HP L + +F Sbjct: 149 --LVEAKKAGKVREIGISNAAIPHLEKLFAASPSPEYYPVVNQIEFHPFLQNQSKNIVRF 206 Query: 230 CFMHDILLTAYSPLGS--HGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSL 287 C H IL+ A+SPL N +K+LAEKY T +L+ Y +++G + + S Sbjct: 207 CQEHGILVEAFSPLAPLARVETNALAETLKRLAEKYKKTEAQVLLRYTLQRGILPVTTSS 266 Query: 288 NPVRISS--SIEFASLTKDELQELNDFGEKYPVR-FIDEPF 325 R+ ++ LT +E+ E+N G+ P R F E F Sbjct: 267 KESRLKESLNLFDFELTDEEVNEINKIGDANPYRAFFHEQF 307 >3WG6-A nrPDB Length = 307 Score = 276 bits (707), Expect = 7e-75, Method: Composition-based stats. Identities = 89/332 (26%), Positives = 149/332 (44%), Gaps = 52/332 (15%) Query: 17 HPKTTEIYFSLNNGVRIPALGLGTANPHEKLA------ETKQAVKAAIKAGYRHIDTAWA 70 H F L+NG +IPA+ GT + K + ++ A+++G+RHID A Sbjct: 3 HMSLAGKEFKLSNGNKIPAVAFGTGTKYFKRGHNDLDKQLIGTLELALRSGFRHIDGAEI 62 Query: 71 YETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLW---------DEVDRSLNESLKALG 121 Y T +G A+K + + R+D+FIT K +L L+ LG Sbjct: 63 YGTNKEIGIALKNV----GLNRKDVFITDKYNSGNHTYDGKHSKHQNPYNALKADLEDLG 118 Query: 122 LEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181 LEYVDL L H+P EK + D +E ++ LE+ Sbjct: 119 LEYVDLYLIHFPYISEK-----------------------SHGFDLVEAWRYLERA---K 152 Query: 182 NDHRVRAIGVSNFSIEYLERLI-KECRVKPTVNQVETHPHLPQME--LRKFCFMHDILLT 238 N+ R IGVSNF+IE L+ ++ P VNQ+E +L + ++ IL+ Sbjct: 153 NEGLARNIGVSNFTIENLKSILDANTDSIPVVNQIEFSAYLQDQTPGIVEYSQQQGILIE 212 Query: 239 AYSPLG--SHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSI 296 AY PLG + G P ++ KL+EKY +L+ + +++G + I + RI+ + Sbjct: 213 AYGPLGPITQGRPGPLDKVLSKLSEKYKRNEGQILLRWVLQRGILPITTTSKEERINDVL 272 Query: 297 EFAS--LTKDELQELNDFGEKYPVRFIDEPFA 326 E L K++ ++ G++ +R + ++ Sbjct: 273 EIFDFELDKEDEDQITKVGKEKTLRQFSKEYS 304 >1PYF-A nrPDB Length = 312 Score = 160 bits (405), Expect = 7e-40, Method: Composition-based stats. Identities = 73/333 (21%), Positives = 133/333 (39%), Gaps = 91/333 (27%) Query: 30 GVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYE---TEPFVGEAIKELLE 86 G+ A+G P+ K+ V+ AI+ G +DTA+ Y +E +GE ++E Sbjct: 17 GLGTNAVGGHNLYPNLNEETGKELVREAIRNGVTMLDTAYIYGIGRSEELIGEVLREF-- 74 Query: 87 DGSIKREDLFITTK----------VWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCF 136 RED+ I TK V+ D + +S++ESLK L +Y+DL H+P Sbjct: 75 ----NREDVVIATKAAHRKQGNDFVFDNSPDFLKKSVDESLKRLNTDYIDLFYIHFP--- 127 Query: 137 EKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSI 196 TP D + + + ++R+IGVSNFS+ Sbjct: 128 -----------DEHTPKD-----------------EAVNALNEMKKAGKIRSIGVSNFSL 159 Query: 197 EYLERLIKECRVKPTVNQVETHPHLPQMELRK----FCFMHDILLTAYSPLGSH------ 246 E L KE V+ ++ +L E K + H+I Y PL S Sbjct: 160 EQL----KEANKDGLVDVLQGEYNLLNREAEKTFFPYTKEHNISFIPYFPLVSGLLAGKY 215 Query: 247 ------GAPNLKIP-----------------LVKKLAEKYNVTGNDLLISYHIRQGT--I 281 +L+ + +AEK+NV +++++++ + I Sbjct: 216 TEDTTFPEGDLRNEQEHFKGERFKENIRKVNKLAPIAEKHNVDIPHIVLAWYLARPEIDI 275 Query: 282 VIPRSLNPVRISSSIEFAS--LTKDELQELNDF 312 +IP + ++ +I+ A L+++++ ++ Sbjct: 276 LIPGAKRADQLIDNIKTADVTLSQEDISFIDKL 308 >1PZ1-A nrPDB Length = 333 Score = 152 bits (385), Expect = 2e-37, Method: Composition-based stats. Identities = 75/357 (21%), Positives = 129/357 (36%), Gaps = 97/357 (27%) Query: 28 NNGVRIPALGLGTAN------PHEKLAETKQAVKAAIKAGYRHIDTAWAYE---TEPFVG 78 + G+ +GLGT + + ++AA+ G IDTA AY +E VG Sbjct: 8 DTGIEASRIGLGTWAIGGTMWGGTDEKTSIETIRAALDQGITLIDTAPAYGFGQSEEIVG 67 Query: 79 EAIKELLEDGSIKREDLFITTKV---W--PVLWDEVDRS-----LNESLKALGLEYVDLL 128 +AIKE + KR+ + + TK W L+ +R+ + SLK L +Y+DL Sbjct: 68 KAIKEYM-----KRDQVILATKTALDWKNNQLFRHANRARIVEEVENSLKRLQTDYIDLY 122 Query: 129 LQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRA 188 HWP ET + ++++Y + ++RA Sbjct: 123 QVHWPDPL----------------------------VPIEETAEVMKELY---DAGKIRA 151 Query: 189 IGVSNFSIEYLE--RLIKECR-VKPTVNQVETHPHLPQMELRKFCFMHDILLTAYSPLGS 245 IGVSNFSIE ++ R + ++P N E + + + + I Y L Sbjct: 152 IGVSNFSIEQMDTFRAVAPLHTIQPPYNLFERE---MEESVLPYAKDNKITTLLYGSLCR 208 Query: 246 H-------------------GAPNLKIPL----------VKKLAE-KYNVTGNDLLISYH 275 P + P + KLA+ +Y + L + + Sbjct: 209 GLLTGKMTEEYTFEGDDLRNHDPKFQKPRFKEYLSAVNQLDKLAKTRYGKSVIHLAVRWI 268 Query: 276 IRQGTIVIP-----RSLNPVRISSSIEFASLTKDELQELNDFGEKYPVRFIDEPFAA 327 + Q I + +S I +L ++ +++N E + F A Sbjct: 269 LDQPGADIALWGARKPGQLEALSE-ITGWTLNSEDQKDINTILENTISDPVGPEFMA 324 >3N6Q-A nrPDB Length = 346 Score = 126 bits (316), Expect = 2e-29, Method: Composition-based stats. Identities = 61/342 (17%), Positives = 130/342 (38%), Gaps = 89/342 (26%) Query: 28 NNGVRIPALGLGTAN--PHEKLAETKQAV-KAAIKAGYRHIDTAWAYETEPFVGEA--IK 82 +G+R+PAL LG + H E+++A+ + A G H D A Y P E + Sbjct: 20 KSGLRLPALSLGLWHNFGHVNALESQRAILRKAFDLGITHFDLANNYGPPPGSAEENFGR 79 Query: 83 ELLEDGSIKREDLFITTK----VWPVLWDE------VDRSLNESLKALGLEYVDLLLQHW 132 L ED + R++L I+TK +WP + + SL++SLK +GLEYVD+ H Sbjct: 80 LLREDFAAYRDELIISTKAGYDMWPGPYGSGGSRKYLLASLDQSLKRMGLEYVDIFYSH- 138 Query: 133 PLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVS 192 TP++++ + + +G+S Sbjct: 139 -------------RVDENTPMEETAS-----------------ALAHAVQSGKALYVGIS 168 Query: 193 NFSIE---YLERLIKECRVKPTVNQVETHP---HLPQMELRKFCFMHDILLTAYSPLGSH 246 ++S E + L++E ++ ++Q + + + L + + A++PL Sbjct: 169 SYSPERTQKMVELLREWKIPLLIHQPSYNLLNRWVDKSGLLDTLQNNGVGCIAFTPLAQG 228 Query: 247 --------------------------------GAPNLKIPLVKKLAEKYNVTGNDLLISY 274 A + L+ ++A++ + + +S+ Sbjct: 229 LLTGKYLNGIPQDSRMHREGNKVRGLTPKMLTEANLNSLRLLNEMAQQRGQSMAQMALSW 288 Query: 275 HI--RQGTIVIPRSLNPVRISSSIEFAS---LTKDELQELND 311 + + T V+ + ++ +++ + + EL +++ Sbjct: 289 LLKDDRVTSVLIGASRAEQLEENVQALNNLTFSTKELAQIDQ 330 >1LQA-A nrPDB Length = 346 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 66/355 (18%), Positives = 117/355 (32%), Gaps = 83/355 (23%) Query: 28 NNGVRIPALGLGT--ANPHEKLAETKQAVKAAIKAGYRHIDTAWAYE----------TEP 75 ++ + + LGLGT A+ + A+ G ID A Y TE Sbjct: 8 HSSLEVSTLGLGTMTFGEQNSEADAHAQLDYAVAQGINLIDVAEMYPVPPRPETQGLTET 67 Query: 76 FVGEAIKELLEDGSIKREDLFITTKVW--------------PVLWDEVDRSLNESLKALG 121 +VG + + RE L I +KV + + +L++SLK L Sbjct: 68 YVGNWLAKHGS-----REKLIIASKVSGPSRNNDKGIRPDQALDRKNIREALHDSLKRLQ 122 Query: 122 LEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDP 181 +Y+DL HWP G S P L+T L+ + Sbjct: 123 TDYLDLYQVHWPQRPTNCFGKLGYSWTDSAPA-----------VSLLDT---LDALAEYQ 168 Query: 182 NDHRVRAIGVSNFSIEYLERLIKECRVK--PTVNQVETHPHLPQME----LRKFCFMHDI 235 ++R IGVSN + + R + P + ++ L L + + Sbjct: 169 RAGKIRYIGVSNETAFGVMRYLHLADKHDLPRIVTIQNPYSLLNRSFEVGLAEVSQYEGV 228 Query: 236 LLTAYSPLG----------------------------SHGAPNLKIPLVKKLAEKYNVTG 267 L AYS LG S + +A ++ + Sbjct: 229 ELLAYSCLGFGTLTGKYLNGAKPAGARNTLFSRFTRYSGEQTQKAVAAYVDIARRHGLDP 288 Query: 268 NDLLISYHIRQGTI--VIPRSLNPVRISSSIEF--ASLTKDELQELNDFGEKYPV 318 + +++ RQ + + + ++ ++IE L++D L E+ + Y Sbjct: 289 AQMALAFVRRQPFVASTLLGATTMDQLKTNIESLHLELSEDVLAEIEAVHQVYTY 343 >3EB3-A nrPDB Length = 327 Score = 94.7 bits (234), Expect = 5e-20, Method: Composition-based stats. Identities = 62/352 (17%), Positives = 110/352 (31%), Gaps = 96/352 (27%) Query: 28 NNGVRIPALGLGTANPHEKLAE---TKQAVKAAIKAGYRHIDTAWAYETEPFVGEA---I 81 +G+R+ LGLGT + + A G DTA Y G+A + Sbjct: 10 KSGLRVSCLGLGTWVTFGGQITDEMAEHLMTLAYDNGINLFDTAEVY----AAGKAEVVL 65 Query: 82 KELLEDGSIKREDLFITTKVWPVL---------WDEVDRSLNESLKALGLEYVDLLLQHW 132 +++ +R L ITTK++ + L SL+ L LEYVD++ + Sbjct: 66 GNIIKKKGWRRSSLVITTKIFAGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANR 125 Query: 133 PLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVS 192 P + ET + + + N G S Sbjct: 126 P----------------------------DPNTPMEETVRAMTHVI---NQGMAMYWGTS 154 Query: 193 NFSIEYLERLIKECR----VKPTVNQVETHPHLPQM---ELRKFCFMHDILLTAYSPLGS 245 +S + R + P Q E H + +L + + +SPL Sbjct: 155 RWSSMEIMEAYSVARQFNLIPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLAC 214 Query: 246 H-------------------GAPNLKIPL--------------VKKLAEKYNVTGNDLLI 272 G LK + ++ +AE+ T L I Sbjct: 215 GIVSGKYDSGIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAI 274 Query: 273 SYHIR-QGT-IVIPRSLNPVRISSSIEFAS----LTKDELQELNDFGEKYPV 318 ++ +R +G V+ + N ++ +I L+ + E++ P Sbjct: 275 AWCLRNEGVSSVLLGASNAEQLMENIGAIQVLPKLSSSIVHEIDSILGNKPY 326 >4R9O-A nrPDB Length = 301 Score = 89.7 bits (221), Expect = 2e-18, Method: Composition-based stats. Identities = 60/304 (19%), Positives = 95/304 (31%), Gaps = 66/304 (21%) Query: 30 GVRIPALGLGTANPHEKLAETKQAV---KAAIKAGYRHIDTAWAYET---EPFVGEAIKE 83 G +G + +Q V + + G +D A Y E GEA+ Sbjct: 14 GPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALTL 73 Query: 84 LLEDGSIKREDLFITTKV--------------WPVLWDEVDRSLNESLKALGLEYVDLLL 129 RE L I TK + + S +SLK L +Y+D+LL Sbjct: 74 APHL----REKLQIVTKCGIATTARAENKLGHYITDRRHIILSAEQSLKNLATDYLDMLL 129 Query: 130 QHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAI 189 H P D E +VR Sbjct: 130 IHRPDPLMDADDVA-------------------------------EAFQHLHQSGKVRHF 158 Query: 190 GVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMEL---RKFCFMHDILLTAYSPLGSH 246 GVSNF+ L NQVE P + L I A+S LG Sbjct: 159 GVSNFTPAQFTLLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRIRPMAWSCLGGG 218 Query: 247 G--APNLKIPL---VKKLAEKYNVTG-NDLLISYHIRQGTIVIP--RSLNPVRISSSIEF 298 PL + +A++ N + ++ ++ +R + +P S R+ +++E Sbjct: 219 RLFNDEAYQPLRQELSVIAQELNASSIEQVVYAWILRLPSQPLPIIGSGKIERVRAALEA 278 Query: 299 ASLT 302 +L+ Sbjct: 279 ETLS 282 >1OG6-A nrPDB Length = 298 Score = 84.3 bits (207), Expect = 8e-17, Method: Composition-based stats. Identities = 56/304 (18%), Positives = 98/304 (32%), Gaps = 68/304 (22%) Query: 30 GVRIPALGLGTANPHEKLAETKQAV---KAAIKAGYRHIDTAWAYET---EPFVGEAIKE 83 G +G + +Q V + + G +D A Y E GEA+K Sbjct: 11 GPEFSRFVMGYWRLMDWNMSARQLVSFIEEHLDLGVTTVDHADIYGGYQCEAAFGEALKL 70 Query: 84 LLEDGSIKREDLFITTKV--------------WPVLWDEVDRSLNESLKALGLEYVDLLL 129 RE + I +K + D + +S +SL L +++DLLL Sbjct: 71 APHL----RERMEIVSKCGIATTAREENVIGHYITDRDHIIKSAEQSLINLATDHLDLLL 126 Query: 130 QHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAI 189 H P ++ + + +VR Sbjct: 127 IHRPD-------------------------------PLMDADEVADAFKHLHQSGKVRHF 155 Query: 190 GVSNFSIEYLERLIKECRVKPTVNQVETHPHLPQMEL---RKFCFMHDILLTAYSPLGSH 246 GVSNF+ L NQVE P + L + A+S LG Sbjct: 156 GVSNFTPAQFALLQSRLPFTLATNQVEISPVHQPLLLDGTLDQLQQLRVRPMAWSCLGGG 215 Query: 247 G------APNLKIPLVKKLAEKYNV-TGNDLLISYHIRQGTIVIP--RSLNPVRISSSIE 297 L+ + +AE+ N + ++ ++ +R + +P S R+ +++E Sbjct: 216 RLFNDDYFQPLRDE-LAVVAEELNAGSIEQVVNAWVLRLPSQPLPIIGSGKIERVRAAVE 274 Query: 298 FASL 301 +L Sbjct: 275 AETL 278 >2CLP-A nrPDB Length = 347 Score = 67.0 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 62/371 (16%), Positives = 111/371 (29%), Gaps = 106/371 (28%) Query: 7 STENI-VENMLHPKTTEIYFSLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHI 65 TEN+ ++M P T + G R+ + +A ++ G+ I Sbjct: 14 GTENLYFQSMARPATVLGAMEM--GRRM------------DAPTSAAVTRAFLERGHTEI 59 Query: 66 DTAWAYETEPFVGEAIKELLEDGSIKRE-DLFITTKVWPVL-----WDEVDRSLNESLKA 119 DTA+ Y E I L + + I TK P+ D + L SLK Sbjct: 60 DTAFVYS--EGQSETILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKR 117 Query: 120 LGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYL 179 L VDL H P ET + + Sbjct: 118 LQCPRVDLFYLHMP----------------------------DHSTPVEETLRA---CHQ 146 Query: 180 DPNDHRVRAIGVSNFSIEYLERLIKECR----VKPTVNQVETHPHLPQMELRKF-CFMH- 233 + + +G+SN++ + + C+ + PTV Q + Q+E F C H Sbjct: 147 LHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVETELFPCLRHF 206 Query: 234 DILLTAYSPLGSH--------GAPNLKIPLV----------------------------K 257 + A++PL + K P+ K Sbjct: 207 GLRFYAFNPLAGGLLTGKYKYEDKDGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEK 266 Query: 258 KLAEKYNVTG---NDLLISY-----HIR--QGTIVIPRSLNPVRISSSIEFASLTKDELQ 307 L Y + + + ++ G VI + ++ ++ A E Sbjct: 267 ALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGPLEPA 326 Query: 308 ELNDFGEKYPV 318 ++ F + + + Sbjct: 327 VVDAFNQAWHL 337 >4EXA-A nrPDB Length = 292 Score = 64.7 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 52/277 (18%), Positives = 92/277 (33%), Gaps = 73/277 (26%) Query: 7 STENI-VENMLHPKTTEIYFSL-NNGVRIPALGLGTANPHEKLA-------------ETK 51 TEN+ ++M+ +++ L + G+ + LGLGT E Sbjct: 14 GTENLYFQSMIRDTLHDLHRPLGDTGLAVSPLGLGTVKFGRDQGVKYPSGFTIPDDREAA 73 Query: 52 QAVKAAIKAGYRHIDTAWAYE-TEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWD--- 107 + A G IDTA AY +E +G ++ +RE I +KV D Sbjct: 74 DLLALARDLGINLIDTAPAYGRSEERLGPLLRG-------QREHWVIVSKVGEEFVDGQS 126 Query: 108 -------EVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTM 160 RS+ SLK L + ++L+L H D + P Sbjct: 127 VFDFSAAHTRRSVERSLKRLETDRIELVLVH-----SDGNDLDILENSEVYPT------- 174 Query: 161 YAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECRVKPTV-NQVETHP 219 + + + A G+S ++E R ++E N E Sbjct: 175 ----------------LAALKREGLIGAYGLSGKTVEGGLRALREGDCAMVTYNLNER-- 216 Query: 220 HLPQMELRKF--CFMHDILL-----TAYSPLGSHGAP 249 + + ++ IL+ + ++ LG+ P Sbjct: 217 --AERPVIEYAAAHAKGILVKKALASGHACLGAGQDP 251 >1GVE-A nrPDB Length = 327 Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 55/332 (16%), Positives = 104/332 (31%), Gaps = 93/332 (28%) Query: 46 KLAETKQAVKAAIKAGYRHIDTAWAYET--EPFVGEAIKELLEDGSIKREDLFITTKVWP 103 + + +V+A ++ G+ IDTA+ Y + + L K + I TK P Sbjct: 20 DVTSSSASVRAFLQRGHTEIDTAFVYANGQSETILGDLGLGLGRSGCK---VKIATKAAP 76 Query: 104 VLWDEVDRS-----LNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGK 158 + + + L SLK L VDL H+P Sbjct: 77 MFGKTLKPADVRFQLETSLKRLQCPRVDLFYLHFP------------------------- 111 Query: 159 TMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECR----VKPTVNQ 214 ET L+ + + + +G+SN+ + + C+ + PTV Q Sbjct: 112 ---DHGTPIEET---LQACHQLHQEGKFVELGLSNYVSWEVAEICTLCKKNGWIMPTVYQ 165 Query: 215 VETHPHLPQMELRKF-CFMH-DILLTAYSPLG----------------SHGAPNLKIP-- 254 + Q+E F C H + A++PL + + P Sbjct: 166 GMYNAITRQVETELFPCLRHFGLRFYAFNPLAGGLLTGRYKYQDKDGKNPESRFFGNPFS 225 Query: 255 ------------------LVKKLAEKYNVT-GNDL--LISY---HIR----QGTIVIPRS 286 + K L Y T + + + + H + QG VI Sbjct: 226 QLYMDRYWKEEHFNGIALVEKALKTTYGPTAPSMISAAVRWMYHHSQLKGTQGDAVILGM 285 Query: 287 LNPVRISSSIEFASLTKDELQELNDFGEKYPV 318 + ++ ++ E ++ F + + + Sbjct: 286 SSLEQLEQNLALVEEGPLEPAVVDAFDQAWNL 317 >2BP1-A nrPDB Length = 360 Score = 63.1 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 54/319 (16%), Positives = 97/319 (30%), Gaps = 91/319 (28%) Query: 58 IKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKRE-DLFITTKV--WPVL---WDEVDR 111 ++ G+ +DTA+ Y E I L G + + I TK W D V Sbjct: 65 LERGHTELDTAFMYSD--GQSETILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRS 122 Query: 112 SLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETY 171 L SLK L VDL H P ET Sbjct: 123 QLETSLKRLQCPQVDLFYLHAP----------------------------DHGTPVEETL 154 Query: 172 KQLEKIYLDPNDHRVRAIGVSNFSIEYLERLIKECR----VKPTVNQVETHPHLPQMELR 227 ++++ + + +G+SN++ + + C+ + PTV Q + Q+E Sbjct: 155 HACQRLH---QEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATTRQVETE 211 Query: 228 KF-CFMH-DILLTAYSPLGSH--------GAPNLKIPLV--------------------- 256 F C H + AY+PL + K P+ Sbjct: 212 LFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRFWKEHHF 271 Query: 257 -------KKLAEKYNVTGNDL---LISY-----HIR--QGTIVIPRSLNPVRISSSIEFA 299 K L Y + + + + ++ G VI + ++ ++ Sbjct: 272 EAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAT 331 Query: 300 SLTKDELQELNDFGEKYPV 318 E ++ F + + + Sbjct: 332 EEGPLEPAVVDAFNQAWHL 350 >2C91-A nrPDB Length = 338 Score = 54.7 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 62/348 (17%), Positives = 113/348 (32%), Gaps = 99/348 (28%) Query: 34 PALGLGTANPHE--KLAETKQAVKAAIKAGYRHIDTAWAY---ETEP-FVGEAIKELLED 87 PA LGT + + +V+A ++ G+ +DTA+ Y ++E G + D Sbjct: 17 PATVLGTMEMGRRMDASASAASVRAFLERGHSELDTAFMYCDGQSENILGGLGLGLGSGD 76 Query: 88 GSIKREDLFITTKV--WPVL---WDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDP 142 ++K I TK W D + L SLK L VDL H P Sbjct: 77 CTVK-----IATKANPWEGKSLKPDSIRSQLETSLKRLQCPRVDLFYLHAP--------- 122 Query: 143 KGISGLVKTPVDDSGKTMYAADGDYLETYKQLEKIYLDPNDHRVRAIGVSNFSIEYLERL 202 TPV+++ L + + + +G+SN++ + + Sbjct: 123 -----DHSTPVEET-----------------LCACHQLHQEGKFVELGLSNYASWEVAEI 160 Query: 203 IKECR----VKPTVNQVETHPHLPQMELRKF-CFMH-DILLTAYSPLGSH--------GA 248 C+ + PTV Q + Q+E C H + AY+PL Sbjct: 161 CTLCKSNGWILPTVYQGMYNATTRQVEAELLPCLRHFGLRFYAYNPLAGGLLTGKYKYED 220 Query: 249 PNLKIPLVK-----------------------KLAEK-----YNVTGNDL---LISY--- 274 + K P+ + L EK Y + + + Sbjct: 221 KDGKQPVGRFFGNNWAETYRNRFWKEHHFEAIALVEKALQTTYGTNAPRMTSAALRWMYH 280 Query: 275 --HIR--QGTIVIPRSLNPVRISSSIEFASLTKDELQELNDFGEKYPV 318 ++ +G VI + ++ ++ E + F + + + Sbjct: 281 HSQLQGTRGDAVILGMSSLEQLEQNLAATEEGPLEPAVVEAFDQAWNM 328 >1OM0-A nrPDB Length = 274 Score = 33.5 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 16/38 (42%), Gaps = 2/38 (5%) Query: 94 DLFITTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQH 131 DLF +W + S+ L+ VDL L+H Sbjct: 94 DLF--DHLWNSYFGGSKPSVPRPFGDAWLDGVDLFLEH 129 >5Z6Q-A nrPDB Length = 392 Score = 32.7 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 27/141 (19%), Positives = 46/141 (32%), Gaps = 15/141 (10%) Query: 26 SLNNGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELL 85 L G+R PA GL P +T A A ++ + + A T +VGE K + Sbjct: 142 ELFTGLRAPARGLLLFGPPGN-GKTMLAKAVAAESNATFFNISAASLTSKYVGEGEKLVR 200 Query: 86 EDGSIKRE----DLFI--TTKVWPVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKI 139 ++ RE +FI + + + + L E L + Sbjct: 201 ALFAVARELQPSIIFIDEVDSLLCERREGEHDAS----RRLKTE----FLIEFDGVQSAG 252 Query: 140 KDPKGISGLVKTPVDDSGKTM 160 D + G P + + Sbjct: 253 DDRVLVMGATNRPQELDEAVL 273 >2ZC8-A nrPDB Length = 369 Score = 32.7 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 43/110 (39%), Gaps = 13/110 (11%) Query: 44 HEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWP 103 + +T + V+ ++ GYR I + V +A++E + ++ + Sbjct: 139 QPSVEDTLRVVERHLEEGYRRIKLKIKPGWDYEVLKAVREAFPEATLTAD--------AN 190 Query: 104 VLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPV 153 + + + + L L L+Y PL ++ + D + + TP+ Sbjct: 191 SAYSLANLAQLKRLDELRLDY-----IEQPLAYDDLLDHAKLQRELSTPI 235 >4EHI-A nrPDB Length = 534 Score = 31.5 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 7/18 (38%), Positives = 11/18 (61%) Query: 62 YRHIDTAWAYETEPFVGE 79 ++HID + Y+ VGE Sbjct: 383 FKHIDGGFVYQNSDEVGE 400 >5Y0V-A nrPDB Length = 578 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 21/62 (33%) Query: 241 SPLGSHGAPNLKIPLVKKLAEKYNVTGNDLLISYHIRQGTIVIPRSLNPVRISSSIEFAS 300 P + PNL + Y ++ + + +G V+P P + + Sbjct: 231 FPFVTTKRPNLYKFGALSPQKVYTKAAIREVVRFGLERGVRVLPEFDAPAHVGEGWQDTD 290 Query: 301 LT 302 LT Sbjct: 291 LT 292 >5ZF1-A nrPDB Length = 301 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 14/23 (60%) Query: 217 THPHLPQMELRKFCFMHDILLTA 239 H + P+ +L +C DI++TA Sbjct: 197 CHRYTPKDKLEAYCRNADIIITA 219 >2FAW-A nrPDB Length = 266 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 23/53 (43%), Gaps = 15/53 (28%) Query: 55 KAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFITTKVWPVLWD 107 K I G+R ID + + D KR +F+T K+WP L++ Sbjct: 195 KKLIDEGFRDID-------------VLNGIAWDQENKR--IFVTGKLWPKLFE 232 >6ET0-A nrPDB Length = 365 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 30/90 (33%), Gaps = 8/90 (8%) Query: 100 KVWPVLWDEVDRSLNESLKA--LGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSG 157 K+ + V ++ +L+ LG + +D + H P F +GI + G Sbjct: 253 KMASFVPTNVPIAMRRALEKAGLGSDDIDYFVFHQPAPFLVKAWAEGIGARPEQYQLTMG 312 Query: 158 KTMYAADGDYLETYKQLEKIYLDPNDHRVR 187 T T + + ++R Sbjct: 313 DTGVMISVSIPYT------LMTGLREGKIR 336 >3Q3N-A nrPDB Length = 500 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 13/27 (48%), Gaps = 3/27 (11%) Query: 106 WDEVDRSLNESLKALGLE---YVDLLL 129 ++ + SL LGL+ Y DL L Sbjct: 295 YEWIIGQFERSLIDLGLDKPWYWDLFL 321 >3A13-A nrPDB Length = 444 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 22/49 (44%) Query: 35 ALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKE 83 LG GT + A +AV+ AI A + I +T + A+++ Sbjct: 389 QLGGGTLGHPDGPAAGARAVRQAIDAIMQGIPLDEYAKTHKELARALEK 437 >5GJU-A nrPDB Length = 205 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 33/163 (20%), Positives = 60/163 (36%), Gaps = 30/163 (18%) Query: 199 LERLIKECRV-KPTVNQVETHPHLPQ-MELRKFCFMHDILLTAYS-PLGSHGAPNLKIPL 255 + + + KP+ Q E PHL ++ A+S PL + P LK P Sbjct: 12 ILEALNDLGYEKPSPIQAECIPHLLNGRDVLGMAQTGSGKTAAFSLPLLQNLDPELKAPQ 71 Query: 256 VKKLA----------------EKYNVTGNDLLI----SYHIR-QGTIVIPRSL--NPVRI 292 + LA K+ N + + Y ++ + P+ + P R+ Sbjct: 72 ILVLAPTRELAVQVAEAMTDFSKHMRGVNVVALYGGQRYDVQLRALRQGPQIVVGTPGRL 131 Query: 293 SSSIEFASLTKDELQ--ELNDFGEKYPVRFID--EPFAAILPE 331 ++ +L +L L++ E + FI+ E A +PE Sbjct: 132 LDHLKRGTLDLSKLSGLVLDEADEMLRMGFIEDVETIMAQIPE 174 >4K91-A nrPDB Length = 346 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 16/73 (21%), Positives = 34/73 (46%), Gaps = 7/73 (9%) Query: 29 NGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDG 88 +G R+ A+ GT + + AET++ + G+R ++ Y+ + + + + Sbjct: 221 DGQRMIAVVFGTNSEQARAAETQKL----LTYGFRFFESRNFYKKGTELTKGLVWKGSEH 276 Query: 89 SIK---REDLFIT 98 +K EDL +T Sbjct: 277 EVKAGLAEDLTMT 289 >3ANK-A nrPDB Length = 398 Score = 28.5 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 28/141 (19%), Positives = 51/141 (36%), Gaps = 19/141 (13%) Query: 49 ETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKRE--DLFITTKVW---- 102 E ++A++ A+K Y +ID Y E + A + E + F T +W Sbjct: 28 EVEEAIEKALKQLYINID----YFGEEYPTPATFNNIYKVMDNTEWTNGFWTGCLWLAYE 83 Query: 103 --------PVLWDEVDRSLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPV- 153 + V LN + L++ DL + P C + + + L T Sbjct: 84 YNQDKKLKNIAHKNVLSFLNRINNRIALDHHDLGFLYTPSCTAEYRINGDVKALEATIKA 143 Query: 154 DDSGKTMYAADGDYLETYKQL 174 D Y G +++ + +L Sbjct: 144 ADKLMERYQEKGGFIQAWGEL 164 >6F0K-D nrPDB Length = 217 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 11/29 (37%) Query: 38 LGTANPHEKLAETKQAVKAAIKAGYRHID 66 G A A + KAGYRH D Sbjct: 24 YGLLAEFSDPAALLHAARQVRKAGYRHFD 52 >3LCV-B nrPDB Length = 281 Score = 28.1 bits (61), Expect = 6.2, Method: Composition-based stats. Identities = 17/83 (20%), Positives = 29/83 (34%), Gaps = 11/83 (13%) Query: 38 LGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVGEAIKELLEDGSIKREDLFI 97 G P AA+ RH+D+A + V A+ + RE L Sbjct: 68 YGAFLPPSPPN------YAAL---LRHLDSAVDAGDDEAVRAALLRAMSVHISTRERLPH 118 Query: 98 TTKVWPVLWDEVDRSLNESLKAL 120 + + L+ + R +L+ L Sbjct: 119 LDEFYRELFRHLPRP--NTLRDL 139 >4NPH-A nrPDB Length = 351 Score = 27.7 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 18/50 (36%) Query: 29 NGVRIPALGLGTANPHEKLAETKQAVKAAIKAGYRHIDTAWAYETEPFVG 78 +G +P + + A +Q + + G R ID+ VG Sbjct: 22 DGRELPDVCWKDYDAMPPPAMVRQPITQPLMTGIRAIDSVATCGEGQRVG 71 >4A35-A nrPDB Length = 441 Score = 27.3 bits (59), Expect = 8.9, Method: Composition-based stats. Identities = 12/63 (19%), Positives = 24/63 (38%) Query: 112 SLNESLKALGLEYVDLLLQHWPLCFEKIKDPKGISGLVKTPVDDSGKTMYAADGDYLETY 171 S++ SL+ EYVD L +H+ + + +++ E + Sbjct: 376 SVSASLENRVCEYVDHLHEHFKYPVMIQRASYMPPKDPGYSTEMKEESVKKHQYPDGEVW 435 Query: 172 KQL 174 K+L Sbjct: 436 KKL 438 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.136 0.410 Lambda K H 0.267 0.0416 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,683,265 Number of Sequences: 36641 Number of extensions: 645034 Number of successful extensions: 2475 Number of sequences better than 10.0: 72 Number of HSP's better than 10.0 without gapping: 109 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 1896 Number of HSP's gapped (non-prelim): 172 length of query: 344 length of database: 10,336,785 effective HSP length: 98 effective length of query: 246 effective length of database: 6,745,967 effective search space: 1659507882 effective search space used: 1659507882 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 59 (27.3 bits)