BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P37387 (330 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3M9X-A nrPDB 618 e-178 4YWH-A nrPDB 474 e-134 4RXU-A nrPDB 143 9e-35 5DTE-A nrPDB 86 2e-17 4RS3-A nrPDB 79 2e-15 4RSM-A nrPDB 79 2e-15 4ZJP-A nrPDB 69 3e-12 1GUD-A nrPDB 60 1e-09 1DBP-A nrPDB 58 7e-09 4WUT-A nrPDB 54 1e-07 4WZZ-A nrPDB 51 8e-07 2VK2-A nrPDB 48 6e-06 5BRA-A nrPDB 47 9e-06 1GCG-A nrPDB 46 3e-05 2IPN-A nrPDB 44 8e-05 5OCP-A nrPDB 44 8e-05 1TM2-A nrPDB 33 0.13 3EDC-A nrPDB 33 0.25 3CTP-A nrPDB 33 0.25 6BGD-A nrPDB 32 0.30 3T95-A nrPDB 31 0.63 3DBI-A nrPDB 29 2.8 2W1V-A nrPDB 29 3.5 3OBT-A nrPDB 28 3.7 1AY9-A nrPDB 28 6.4 5XZ7-A nrPDB 28 6.5 4S3K-A nrPDB 28 6.9 >3M9X-A nrPDB Length = 313 Score = 618 bits (1594), Expect = e-178, Method: Compositional matrix adjust. Identities = 307/307 (100%), Positives = 307/307 (100%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD Sbjct: 1 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 60 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI Sbjct: 61 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 120 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN Sbjct: 121 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 180 Query: 204 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV Sbjct: 181 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 240 Query: 264 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG 323 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG Sbjct: 241 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG 300 Query: 324 FHKESEL 330 FHKESEL Sbjct: 301 FHKESEL 307 >4YWH-A nrPDB Length = 332 Score = 474 bits (1221), Expect = e-134, Method: Compositional matrix adjust. Identities = 233/302 (77%), Positives = 265/302 (87%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 K++ IGM+IDDLRLERWQKDRDIFVKKAESLGAKV VQSANG++ Q+SQIENM+N+ VD Sbjct: 24 KDLTIGMSIDDLRLERWQKDRDIFVKKAESLGAKVLVQSANGDDSAQISQIENMLNKNVD 83 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 VLVIIP+NG VLSNV+ EAK+EG+KVLAYDR+IN+AD+DFY+SFDNEKVGELQA A++ Sbjct: 84 VLVIIPHNGDVLSNVISEAKKEGVKVLAYDRLINNADLDFYVSFDNEKVGELQADAIIKE 143 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 P+GNYFLMGGSPVDNNAKLFR GQMKVL+P +DSGKIKVVGDQWVD WL E AL+IMEN Sbjct: 144 KPEGNYFLMGGSPVDNNAKLFRKGQMKVLQPLIDSGKIKVVGDQWVDSWLAEKALQIMEN 203 Query: 204 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 ALTAN N IDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLA IKRI GTQTMTV Sbjct: 204 ALTANKNNIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAAIKRIVEGTQTMTV 263 Query: 264 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG 323 YKPIT LA+ AAE++V LG ++ + + LNNGLK+V + LL PI V K+NI TVIKDG Sbjct: 264 YKPITNLADKAAELSVALGKEEKLEPNAKLNNGLKEVDAYLLDPIVVTKDNIDSTVIKDG 323 Query: 324 FH 325 FH Sbjct: 324 FH 325 >4RXU-A nrPDB Length = 367 Score = 143 bits (361), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 102/337 (30%), Positives = 171/337 (50%), Gaps = 32/337 (9%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 +++ +G+ + RW +D F + + G +V + + G+ + +E +I +G+ Sbjct: 29 QQLAVGIVLPTKDEPRWIQDETRFREALQQAGYQVEILFSQGSSAKEKENVEALIAKGIK 88 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDAD-IDFYISFDNEKVGELQAKALVD 142 VL+I P++G + + A+ G+KV++YDR+I + D +D+Y++FD+ VG QA+ LVD Sbjct: 89 VLIICPHDGTAAAAAAEAARAAGVKVISYDRLIRETDAVDYYVTFDSIAVGAQQAQYLVD 148 Query: 143 IVP-QGN-YFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKI------------------- 181 GN +L G+ DNNA LF G KVL+P + G Sbjct: 149 HASGTGNPLYLYAGAASDNNAFLFFEGAWKVLQPKIADGTFVIKNSSEAVALQNKLDLTR 208 Query: 182 ----KVVGDQWVDGWLPENALKIMENALTA----NNNKIDAVVASNDATAGGAIQALSAQ 233 K++G Q W A + E LTA + K+ ++A ND TA A +A Sbjct: 209 DEMAKIIG-QVTTNWDFNTAKNLAEANLTAATAADKGKV-YILAPNDGTARAIADAFAAD 266 Query: 234 GLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTL 293 + ++GQDA+ A ++ I G Q+MTV+K + L A + AV L Q+P+A T Sbjct: 267 KDVTEYFVTGQDAEKASVQYIIDGRQSMTVFKDVRTLVQDAIKAAVALLQDQQPEARGTY 326 Query: 294 NNGLKDVPSRLLTPIDVNKNNIKDTVIKDGFHKESEL 330 NNG KDVP+ + V ++N++ +I G++ S+ Sbjct: 327 NNGKKDVPAIQSPVVTVTRDNVRAALIDSGYYSASDF 363 >5DTE-A nrPDB Length = 311 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 71/230 (30%), Positives = 113/230 (49%), Gaps = 22/230 (9%) Query: 41 QKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVK 100 QKD D+ V+ AE + E + +ENMI + VD +++ P + + Sbjct: 54 QKDIDLIVQVAEK----------EDSTEQLVGLVENMIAKKVDAIIVTPNDSIAFIPAFQ 103 Query: 101 EAKQEGIKVLAYD-----RMINDADIDF-YISFDNEKVGELQAKALVDIV-PQGNYFLMG 153 +A++ GI ++ D + A + F Y+ DN G L+AK L + + +GN ++ Sbjct: 104 KAEKAGIPIIDLDVRLDAKAAEAAGLKFNYVGVDNFNGGYLEAKNLAEAIGKKGNVAILE 163 Query: 154 GSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKID 213 G P +N + + G +K Y D IK+V Q + W E AL + N LTAN N I+ Sbjct: 164 GIPGVDNGEQRKGGALKAFAEYPD---IKIVASQSAN-WETEQALNVTTNILTANPN-IN 218 Query: 214 AVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 + A+ND A GA+ A+ GL+GKV +SG D I+ + G T+ Sbjct: 219 GIFAANDNMAIGAVTAVENAGLAGKVLVSGYDGIPLAIEYVKQGKMQNTI 268 >4RS3-A nrPDB Length = 327 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 77/277 (27%), Positives = 141/277 (50%), Gaps = 13/277 (4%) Query: 18 NVAAHAKEVKIGMAIDDLR--LERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIE 75 + AA++ +IG+ + D+ + ++ D + K A ++ ++ SAN + TQ SQ++ Sbjct: 5 DTAANSDTKRIGVTVYDMSSFITEGKEGMDTYAK-ANNI--ELVWNSANNDVSTQASQVD 61 Query: 76 NMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGEL 135 ++IN+GVD ++++P L V AK +GI +LA + + D+ + D+ G Sbjct: 62 SLINQGVDAIIVVPVQADSLGPQVASAKSKGIPLLAVNAALETPDLAGNVQPDDVAAGAQ 121 Query: 136 QAKALVD-IVPQGNYFLMGGSPVDNNAKLFRA-GQMKVLKPYVDSGKIKVVGDQWVDGWL 193 + + + D + +GN ++ G P+ + ++ R G +VL Y D IKV+ + W Sbjct: 122 EMQMMADRLGGKGNIVILQG-PLGGSGEINRGKGIDQVLAKYPD---IKVLAKDTAN-WK 176 Query: 194 PENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKR 253 + A+ M+N +++ +ID VVA ND GA+QAL G +G V I G D G+ Sbjct: 177 RDEAVNKMKNWISSFGPQIDGVVAQNDDMGLGALQALKEAGRTG-VPIVGIDGIEDGLNA 235 Query: 254 IAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKAD 290 + +G T + T+ + +A L G++ K D Sbjct: 236 VKSGDFIGTSLQNGTVELSAGLAVADALVKGEDVKTD 272 >4RSM-A nrPDB Length = 327 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 71/249 (28%), Positives = 126/249 (50%), Gaps = 27/249 (10%) Query: 20 AAHAKEVKIGMAIDDLR---------LERWQKDRDIFVKKAESLGAKVFVQSANGNEETQ 70 AA++ +IG+ + D+ ++ + KD +I ++ SAN + TQ Sbjct: 7 AANSDTTRIGVTVYDMSSFITAGKEGMDAYAKDNNI----------ELIWNSANLDVSTQ 56 Query: 71 MSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNE 130 SQ+++MIN+GVD ++++P L+ V AK +GI ++ + ++ DI + D+ Sbjct: 57 ASQVDSMINQGVDAIIVVPVQADSLAPQVASAKAKGIPLVPVNAALDSKDIAGNVQPDDV 116 Query: 131 KVGELQAKALVD-IVPQGNYFLMGGSPVDNNAKLFRA-GQMKVLKPYVDSGKIKVVGDQW 188 G + + + D + +GN ++ G P+ + +L R+ G +VL Y D IKV+ Sbjct: 117 AAGAQEMQMMADRLGGKGNIVILQG-PLGQSGELDRSKGIEQVLAKYPD---IKVLAKDT 172 Query: 189 VDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADL 248 + W + A+ M+N ++ +ID VVA ND GA+QAL G +G V I G D Sbjct: 173 AN-WKRDEAVNKMKNWISGFGPQIDGVVAQNDDMGLGALQALKESGRTG-VPIVGIDGIE 230 Query: 249 AGIKRIAAG 257 G+ + +G Sbjct: 231 DGLNAVKSG 239 >4ZJP-A nrPDB Length = 292 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 66/243 (27%), Positives = 111/243 (45%), Gaps = 17/243 (6%) Query: 49 KKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIK 108 KKA LG K+ V + + ++S +E++ RG VL+I P + +SN V A + I Sbjct: 48 KKATELGYKLVVLDSQNDPSKELSNVEDLTVRGAKVLLINPTDSAAVSNAVAIANRNKIP 107 Query: 109 VLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYF-----LMGGSPVDNNAKL 163 V+ DR ++ +I+ DN G++ + + G L G S + Sbjct: 108 VITLDRGAAKGEVVSHIASDNVAGGKMAGDFIAQKLGDGAKVIQLEGLAGTSAARERGEG 167 Query: 164 FRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATA 223 F K +++ K V+ Q D + L + EN L A+ + A+ A ND A Sbjct: 168 F--------KQAIEAHKFDVLASQPAD-FDRTKGLNVTEN-LLASKGSVQAIFAQNDEMA 217 Query: 224 GGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGN 283 GA++A+SA G KV + G D G+K + +G TV + L+ + E A ++ Sbjct: 218 LGALRAISAAG--KKVLVVGFDGTEDGVKAVKSGKLAATVAQQPELIGSLGVETADKILK 275 Query: 284 GQE 286 G++ Sbjct: 276 GEK 278 >1GUD-A nrPDB Length = 288 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 60/225 (26%), Positives = 104/225 (46%), Gaps = 16/225 (7%) Query: 50 KAESLGAKV--FVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGI 107 +A++LG V F + G+ ++Q+ E++ N+ + P + L V A ++GI Sbjct: 26 EAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIAFAPLSSVNLVMPVARAWKKGI 85 Query: 108 KVLAYDRMIN-------DADIDFYISFDNEKVGELQAKALVDIVPQ--GNYFLMGGSPVD 158 ++ D I+ +++ +++ DN VG A ++D + G ++ G + Sbjct: 86 YLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAVGAKGASFIIDKLGAEGGEVAIIEGKAGN 145 Query: 159 NNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVAS 218 + + R G + K + +IK+V Q D W AL + N L N N I A+ + Sbjct: 146 ASGEARRNGATEAFK---KASQIKLVASQPAD-WDRIKALDVATNVLQRNPN-IKAIYCA 200 Query: 219 NDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 ND A G QA++ G +GKV + G D K + AG T TV Sbjct: 201 NDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAGQMTATV 245 >1DBP-A nrPDB Length = 271 Score = 57.8 bits (138), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 98/215 (45%), Gaps = 6/215 (2%) Query: 49 KKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIK 108 K+A+ LG + V + N +++ ++++ RG +L+I P + + N VK A Q I Sbjct: 25 KEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILLINPTDSDAVDNAVKMANQANIP 84 Query: 109 VLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQ 168 V+ DR ++ +I+ DN G++ + +G + +A R Sbjct: 85 VITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGEGAKVIELQGIAGTSAARERG-- 142 Query: 169 MKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQ 228 + + V + K V+ Q D + L +M+N LTA+ + + AV A ND A GA++ Sbjct: 143 -EGFQQAVAAHKFNVLASQPAD-FDRIKGLNVMQNLLTAHPD-VQAVFAQNDEMALGALR 199 Query: 229 ALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 AL G S V + G D G K + G T+ Sbjct: 200 ALQTAGKS-DVMVVGFDGTPDGEKAVNDGKLAATI 233 >4WUT-A nrPDB Length = 313 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 51/188 (27%), Positives = 92/188 (48%), Gaps = 21/188 (11%) Query: 70 QMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISF-- 127 Q++ +EN +NR VD +++ P + L VK+A + I V+ D M++ +Y +F Sbjct: 71 QVNMVENAVNRKVDAILLAPSDPDALVPAVKKAWEARIPVVIIDSMLSKDAEKYYQAFLA 130 Query: 128 -DNEKVGELQAKALVDIV-PQG-----NYFLMGGSPVDNNAKLFRAGQMKVLKPYVDS-G 179 DN+ GEL AKA++ V +G +Y GS + G++ Y+ + Sbjct: 131 TDNKAAGELAAKAMIQKVGTEGKIAVMSYVAGAGSEI---------GRVGGFTDYIKANS 181 Query: 180 KIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKV 239 K+++VG + + AL + L AN + + + +N+ TA G +A+ G +GK+ Sbjct: 182 KLQIVGPYYSQSQMA-TALNQTTDVLAANAD-LKGIFGANEPTAIGMGRAIKQAGKAGKL 239 Query: 240 AISGQDAD 247 G D + Sbjct: 240 VAIGFDGN 247 >4WZZ-A nrPDB Length = 371 Score = 50.8 bits (120), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 67/256 (26%), Positives = 115/256 (44%), Gaps = 21/256 (8%) Query: 41 QKDRDIFVKKAESLGAKVFVQSA-NGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVV 99 QK+ + + + E+ G K +Q + E Q++ I N I++GVD + I + L + Sbjct: 70 QKESEGYKQVIEANGGKCVIQEPKSATAEDQITCINNAISQGVDCIAIAANDTDALEPAL 129 Query: 100 KEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQ-AKALVDIV-----PQGNYFLMG 153 EAK +GI VL+ D N +++ + G Q A+AL+D + G++ ++ Sbjct: 130 TEAKNQGIHVLSLDSATNANSRKVFVN----QAGTTQIAQALMDAILDISGGSGDWAVLS 185 Query: 154 GSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKID 213 + N + G MK + K+ ++G + D + + E L A+ N I Sbjct: 186 AASTATNQNAWIDG-MKTVMQDSKYSKLNLIGVYYGDDEY-QASCDQTEAILAADPN-IK 242 Query: 214 AVVASNDATAGGAIQALSAQGLSGKVAISG-----QDADLAGIKRIAAGTQTMTVYKPIT 268 + A A + L +GLSGKV ++G + AD G + M ++ PI Sbjct: 243 VICAPTTVGIMAAAKVLQDKGLSGKVKLTGLGLPSEMADYIGDDDQHS-CPYMFLWNPIQ 301 Query: 269 LLANTAAEIAVELGNG 284 L N AA ++ L NG Sbjct: 302 -LGNLAAYASISLVNG 316 >2VK2-A nrPDB Length = 306 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 61/205 (29%), Positives = 91/205 (44%), Gaps = 18/205 (8%) Query: 50 KAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKV 109 +AE G + + +E Q+ + + + +GVD + I P V+KEAK I V Sbjct: 27 EAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEAKDAEIPV 86 Query: 110 LAYDRMINDADIDFY---ISFDNEKVGELQAKALVDIV---PQGNYFLMG--GSPVDNNA 161 DR I+ D Y ++ DN G+L LV V P L G G+ V + Sbjct: 87 FLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVGASVAIDR 146 Query: 162 KLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNN--KIDAVVASN 219 K A +K ++ IK++ Q D + ++ME+ + A NN I V A N Sbjct: 147 KKGFAEAIK------NAPNIKIIRSQSGD-FTRSKGKEVMESFIKAENNGKNICMVYAHN 199 Query: 220 DATAGGAIQALSAQGL-SGKVAISG 243 D GAIQA+ GL GK ++G Sbjct: 200 DDMVIGAIQAIKEAGLKPGKDILTG 224 >5BRA-A nrPDB Length = 350 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 51/192 (26%), Positives = 97/192 (50%), Gaps = 16/192 (8%) Query: 59 FVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMIND 118 V + + Q+ +EN+I +GVD + I+P++ + + V+K+A++ GI V++++ N Sbjct: 79 MVGPSQADAAAQVQIVENLIAQGVDAIAIVPFSVEAVEPVLKKARERGIVVISHEAS-NI 137 Query: 119 ADIDFYI-SFDNEKVGELQAKAL-VDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLK--- 173 ++D+ I +FDN+ G K L + +G Y GS + + G ++ K Sbjct: 138 QNVDYDIEAFDNKAYGANLMKELGKSMGGKGKYVTTVGSLTSKSQMEWIDGAVEYQKANF 197 Query: 174 PYVD--SGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALS 231 P + +G+++ D D N LK A+TA + I ++ + T+ GA + ++ Sbjct: 198 PEMSEATGRLETYDDANTD----YNKLK---EAMTAYPD-ITGILGAPMPTSAGAGRLIA 249 Query: 232 AQGLSGKVAISG 243 GL GKV +G Sbjct: 250 EGGLKGKVFFAG 261 >1GCG-A nrPDB Length = 309 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 55/258 (21%), Positives = 107/258 (41%), Gaps = 45/258 (17%) Query: 57 KVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDR-- 114 ++ + + ++ Q QI+ ++ +GV L I + V+++A+ + + V+ +++ Sbjct: 35 QLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEP 94 Query: 115 ---MINDADIDFYISFDNEKVGELQAKALV---------DIVPQG--NYFLMGGSPVDNN 160 ++ D +Y+ D+++ G +Q + D+ G Y L+ G P + Sbjct: 95 SRKALDSYDKAYYVGTDSKESGVIQGDLIAKHWQANQGWDLNKDGKIQYVLLKGEPGHPD 154 Query: 161 A-------------KLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTA 207 A K + Q+ + D+ + K D W+ G Sbjct: 155 AEARTTYVVKELNDKGIQTEQLALDTAMWDTAQAKDKMDAWLSG---------------P 199 Query: 208 NNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPI 267 N NKI+ V+A+NDA A GA++AL A S + + G DA + + +G TV Sbjct: 200 NANKIEVVIANNDAMAMGAVEALKAHNKSS-IPVFGVDALPEALALVKSGAMAGTVLNDA 258 Query: 268 TLLANTAAEIAVELGNGQ 285 A ++A L G+ Sbjct: 259 NNQAKATFDLAKNLAEGK 276 >2IPN-A nrPDB Length = 318 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 53/258 (20%), Positives = 108/258 (41%), Gaps = 45/258 (17%) Query: 57 KVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDR-- 114 ++ + + ++ Q QI+ ++ +GV L I + V+++A+ + + V+ +++ Sbjct: 36 QLLMNDSQNDQSKQNDQIDVLLAKGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEP 95 Query: 115 ---MINDADIDFYISFDNEKVGELQAKALV---------DIVPQGN--YFLMGGSPVDNN 160 ++ D +Y+ D+++ G +Q + D+ G + L+ G P + Sbjct: 96 SRKALDSYDKAYYVGTDSKESGIIQGDLIAKHWAANQGWDLNKDGQIQFVLLKGEPGHPD 155 Query: 161 A-------------KLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTA 207 A K + Q+++ D+ + K D W+ G Sbjct: 156 AEARTTYVIKELNDKGIKTEQLQLDTAMWDTAQAKDKMDAWLSG---------------P 200 Query: 208 NNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPI 267 N NKI+ V+A+ND A GA++AL A S + + G DA + + +G TV Sbjct: 201 NANKIEVVIANNDCMAMGAVEALKAHNKSS-IPVFGVDALPEALALVKSGALAGTVLNDA 259 Query: 268 TLLANTAAEIAVELGNGQ 285 A ++A L +G+ Sbjct: 260 NNQAKATFDLAKNLADGK 277 >5OCP-A nrPDB Length = 302 Score = 44.3 bits (103), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 55/180 (30%), Positives = 87/180 (48%), Gaps = 13/180 (7%) Query: 63 ANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADID 122 A +E Q+ + + I +GVD ++I P V+KEAK+ I V+ DR I D Sbjct: 38 AQQKQENQIKAVRSFIAQGVDAIIIAPVVETGWKPVLKEAKRAKIPVVIVDRNIKVDDDS 97 Query: 123 FY---ISFDNEKVGELQAKALVDIVPQGNYFL--MGGSPVDNNAKLFR-AGQMKVLKPYV 176 + I+ D + G + L+D QGN + + G+ V A + R AG +V+ Y Sbjct: 98 LFLTRIASDFSEEGRKIGQWLMDKT-QGNCDIAELQGT-VGATAAIDRAAGFNQVIANYP 155 Query: 177 DSGKIKVVGDQWVDGWLPENALKIMENALTANNNK-IDAVVASNDATAGGAIQALSAQGL 235 ++ K+V Q + ++ME L A N + + AV + ND A GA+QA+ GL Sbjct: 156 NA---KIVRSQ-TGEFTRAKGKEVMEGFLKAQNGQPLCAVWSHNDEMALGAVQAIKEAGL 211 >1TM2-A nrPDB Length = 316 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 28/56 (50%) Query: 70 QMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYI 125 Q+ + N +N+G D +++ + L +K A Q G+K+L +D +YI Sbjct: 49 QVQLVNNFVNQGYDAIIVSAVSPDGLCPALKRAMQRGVKILTWDSDTKPECRSYYI 104 >3EDC-A nrPDB Length = 360 Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust. Identities = 67/273 (24%), Positives = 116/273 (42%), Gaps = 24/273 (8%) Query: 28 IGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSA-NGNEETQMSQIENMINRGVDVLV 86 IG+A L L + +A+ LGA V V E + + N++ + V L+ Sbjct: 64 IGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLAQRVSGLI 123 Query: 87 I-IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVP 145 I P + Q + EA + L D ++D I F +E L + LV + Sbjct: 124 INYPLDDQ--DAIAVEAACTNVPALFLD--VSDQTPINSIIFSHEDGTRLGVEHLVALGH 179 Query: 146 QGNYFLMGGSPVDN-NAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENA 204 Q L G P+ + +A+L AG K Y+ +I+ + ++ D W +A+ + Sbjct: 180 QQIALLAG--PLSSVSARLRLAGWHK----YLTRNQIQPIAEREGD-W---SAMSGFQQT 229 Query: 205 LTANNNKI--DAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAGTQT 260 + N I A++ +ND A GA++A++ GL +++ G D I T Sbjct: 230 MQMLNEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYIPPLT-- 287 Query: 261 MTVYKPITLLANTAAEIAVELGNGQEPKADTTL 293 T+ + LL T+ + ++L GQ K + L Sbjct: 288 -TIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLL 319 >3CTP-A nrPDB Length = 330 Score = 32.7 bits (73), Expect = 0.25, Method: Compositional matrix adjust. Identities = 30/128 (23%), Positives = 65/128 (50%), Gaps = 9/128 (7%) Query: 162 KLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKI--DAVVASN 219 ++F A +++ K ++D + K + +++ + + +K++E + + + + D + N Sbjct: 182 EVFEATELR-YKGFLDGARAKDLEIDFIE-FQHDFQVKMLEEDINSMKDIVNYDGIFVFN 239 Query: 220 DATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEI 277 D A ++AL +G+S +V I G D G + T T+ +PI LA T E+ Sbjct: 240 DIAAATVMRALKKRGVSIPQEVQIIGFDNSFIGELLYPSLT---TINQPIEALAYTIIEL 296 Query: 278 AVELGNGQ 285 +++ NG+ Sbjct: 297 LIKIINGE 304 >6BGD-A nrPDB Length = 378 Score = 32.3 bits (72), Expect = 0.30, Method: Compositional matrix adjust. Identities = 47/183 (25%), Positives = 73/183 (39%), Gaps = 39/183 (21%) Query: 116 INDADIDFYISFDNEKVGELQAKALVDIVPQG------------NYFLMGGSPVDNNAKL 163 +N D +Y+ FD + G +Q K ++D + Y L G N++K+ Sbjct: 35 MNWNDKTYYVGFDAKFGGSIQGKMILDFLASSESSVDRNGDGIIGYVLCIGDVGHNDSKV 94 Query: 164 FRAGQMKVLKPYV---DSGKIK----VVGDQWVDGWLPENALKIMENALTANNN------ 210 G + L + D G+ K VVG + E + TAN N Sbjct: 95 RTEGIRRALGTWTGSSDPGQAKEGQAVVGGKSYKVVELEGKAMTGTDGSTANTNSATESM 154 Query: 211 ---------KIDAVVASNDATAGGAIQALS-AQGLSGKVAISGQDADLAGIKRIAAGTQT 260 KID V+++ND A G +QA + +GL I G DA+ ++ + G T Sbjct: 155 GSWVAKFADKIDLVISNNDGMAMGCLQASNYPRGL----PIFGYDANADAVESVGKGELT 210 Query: 261 MTV 263 TV Sbjct: 211 GTV 213 >3T95-A nrPDB Length = 335 Score = 31.2 bits (69), Expect = 0.63, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 25/44 (56%) Query: 70 QMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYD 113 Q+ I N +N+G + +V+ + L +K A Q G+K+L +D Sbjct: 68 QVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRGVKILTWD 111 >3DBI-A nrPDB Length = 338 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 1/45 (2%) Query: 192 WLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLS 236 W P + + +E L K A+VASND A GA++AL +G++ Sbjct: 224 WTPASGAEGVE-MLLERGAKFSALVASNDDMAIGAMKALHERGVA 267 >2W1V-A nrPDB Length = 276 Score = 28.9 bits (63), Expect = 3.5, Method: Compositional matrix adjust. Identities = 16/70 (22%), Positives = 35/70 (50%), Gaps = 1/70 (1%) Query: 96 SNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGS 155 ++V+EA ++G +++ N Y EK+ + L ++ + + +L+GGS Sbjct: 25 CSLVREAAKQGANIVSLPECFNSPYGTTYFPDYAEKIPGESTQKLSEVAKESSIYLIGGS 84 Query: 156 -PVDNNAKLF 164 P ++ KL+ Sbjct: 85 IPEEDAGKLY 94 >3OBT-A nrPDB Length = 434 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 22/39 (56%) Query: 88 IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYIS 126 I Y GQ+L NV+K+ +K +IND ID YI+ Sbjct: 219 IVYEGQILRNVIKDYWGNPLKFDTEYYIINDNYIDRYIA 257 >1AY9-A nrPDB Length = 108 Score = 27.7 bits (60), Expect = 6.4, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 26/40 (65%), Gaps = 2/40 (5%) Query: 181 IKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASND 220 +K GD +DG + + L I+++A+TA++ D V+A+ D Sbjct: 23 VKASGDSMIDGGISDGDLLIVDSAITASHG--DIVIAAVD 60 >5XZ7-A nrPDB Length = 330 Score = 27.7 bits (60), Expect = 6.5, Method: Compositional matrix adjust. Identities = 29/80 (36%), Positives = 37/80 (46%), Gaps = 12/80 (15%) Query: 59 FVQSANGNE----ETQMSQIENMINRGVDVLVII----PYNG-QVLSNVVKEAKQEGIKV 109 F+ SA E E + IEN+ RG++ LV+I Y G Q +S KE + GI Sbjct: 67 FLYSARCPEFKEQEVRKVAIENLRKRGIEGLVVIGGDGSYRGAQRISEECKEIQTIGIPG 126 Query: 110 LAYDRMINDADIDFYISFDN 129 D IN DF I FD Sbjct: 127 -TIDNDINGT--DFTIGFDT 143 >4S3K-A nrPDB Length = 436 Score = 27.7 bits (60), Expect = 6.9, Method: Compositional matrix adjust. Identities = 15/49 (30%), Positives = 29/49 (59%), Gaps = 1/49 (2%) Query: 94 VLSNVVKEAKQEGIKVLAYD-RMINDADIDFYISFDNEKVGELQAKALV 141 +L+N+VK AK++ + + +D + AD + YI+F + LQ + L+ Sbjct: 200 LLNNIVKTAKEQNFRDIHFDFEFLRPADKEAYIAFLQKAKKRLQDEQLL 248 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3M9X-A nrPDB 362 e-101 4YWH-A nrPDB 336 7e-93 4RXU-A nrPDB 257 4e-69 4RS3-A nrPDB 228 2e-60 4RSM-A nrPDB 216 1e-56 4ZJP-A nrPDB 215 2e-56 1DBP-A nrPDB 206 1e-53 1GUD-A nrPDB 185 2e-47 5DTE-A nrPDB 183 1e-46 4WZZ-A nrPDB 180 6e-46 5OCP-A nrPDB 169 1e-42 2IPN-A nrPDB 167 6e-42 2VK2-A nrPDB 167 7e-42 1GCG-A nrPDB 166 1e-41 4WUT-A nrPDB 160 9e-40 5BRA-A nrPDB 149 1e-36 Sequences not found previously or not previously below threshold: 3D02-A nrPDB 112 2e-25 4PZ0-A nrPDB 104 8e-23 5BQ3-A nrPDB 93 1e-19 4KVF-A nrPDB 91 6e-19 3EJW-A nrPDB 87 1e-17 1TM2-A nrPDB 87 1e-17 3T95-A nrPDB 86 3e-17 3EDC-A nrPDB 78 7e-15 3OQN-A nrPDB 75 5e-14 1RZR-D nrPDB 73 2e-13 2IKS-A nrPDB 72 3e-13 6BGD-A nrPDB 72 3e-13 2PUG-A nrPDB 72 4e-13 3CTP-A nrPDB 67 1e-11 3DBI-A nrPDB 66 2e-11 6DSP-A nrPDB 66 3e-11 3O75-A nrPDB 64 1e-10 5YSZ-A nrPDB 63 2e-10 3H5O-A nrPDB 63 2e-10 3BIL-A nrPDB 62 3e-10 8ABP-A nrPDB 60 1e-09 3GYB-A nrPDB 60 1e-09 4KZK-A nrPDB 58 9e-09 3ROT-A nrPDB 55 5e-08 3JVD-A nrPDB 49 3e-06 4YP9-A nrPDB 48 5e-06 5UFH-A nrPDB 41 7e-04 4CBI-A nrPDB 35 0.049 4WHB-E nrPDB 34 0.080 5WSO-A nrPDB 33 0.20 5ZEB-b nrPDB 32 0.26 1BVU-A nrPDB 32 0.43 5WX1-A nrPDB 31 0.74 2HIX-A nrPDB 31 0.94 6DZI-8 nrPDB 31 1.1 3S99-A nrPDB 31 1.1 5V7X-A nrPDB 30 1.2 6FXC-Ab nrPDB 30 1.6 1A6D-B nrPDB 30 1.7 1X18-E nrPDB 29 2.2 5LK8-C nrPDB 29 2.5 5ND9-b nrPDB 29 2.7 3QM3-A nrPDB 29 2.8 5MYJ-AB nrPDB 28 4.7 3QY6-A nrPDB 28 5.2 1SO4-A nrPDB 28 5.2 6QGB-A nrPDB 28 5.2 1Z15-A nrPDB 28 6.8 >3M9X-A nrPDB Length = 313 Score = 362 bits (930), Expect = e-101, Method: Composition-based stats. Identities = 307/307 (100%), Positives = 307/307 (100%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD Sbjct: 1 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 60 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI Sbjct: 61 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 120 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN Sbjct: 121 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 180 Query: 204 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV Sbjct: 181 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 240 Query: 264 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG 323 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG Sbjct: 241 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG 300 Query: 324 FHKESEL 330 FHKESEL Sbjct: 301 FHKESEL 307 >4YWH-A nrPDB Length = 332 Score = 336 bits (862), Expect = 7e-93, Method: Composition-based stats. Identities = 233/304 (76%), Positives = 266/304 (87%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 K++ IGM+IDDLRLERWQKDRDIFVKKAESLGAKV VQSANG++ Q+SQIENM+N+ VD Sbjct: 24 KDLTIGMSIDDLRLERWQKDRDIFVKKAESLGAKVLVQSANGDDSAQISQIENMLNKNVD 83 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 VLVIIP+NG VLSNV+ EAK+EG+KVLAYDR+IN+AD+DFY+SFDNEKVGELQA A++ Sbjct: 84 VLVIIPHNGDVLSNVISEAKKEGVKVLAYDRLINNADLDFYVSFDNEKVGELQADAIIKE 143 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 P+GNYFLMGGSPVDNNAKLFR GQMKVL+P +DSGKIKVVGDQWVD WL E AL+IMEN Sbjct: 144 KPEGNYFLMGGSPVDNNAKLFRKGQMKVLQPLIDSGKIKVVGDQWVDSWLAEKALQIMEN 203 Query: 204 ALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 ALTAN N IDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLA IKRI GTQTMTV Sbjct: 204 ALTANKNNIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAAIKRIVEGTQTMTV 263 Query: 264 YKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVIKDG 323 YKPIT LA+ AAE++V LG ++ + + LNNGLK+V + LL PI V K+NI TVIKDG Sbjct: 264 YKPITNLADKAAELSVALGKEEKLEPNAKLNNGLKEVDAYLLDPIVVTKDNIDSTVIKDG 323 Query: 324 FHKE 327 FH + Sbjct: 324 FHSK 327 >4RXU-A nrPDB Length = 367 Score = 257 bits (657), Expect = 4e-69, Method: Composition-based stats. Identities = 100/336 (29%), Positives = 168/336 (50%), Gaps = 30/336 (8%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 +++ +G+ + RW +D F + + G +V + + G+ + +E +I +G+ Sbjct: 29 QQLAVGIVLPTKDEPRWIQDETRFREALQQAGYQVEILFSQGSSAKEKENVEALIAKGIK 88 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDAD-IDFYISFDNEKVGELQAKALVD 142 VL+I P++G + + A+ G+KV++YDR+I + D +D+Y++FD+ VG QA+ LVD Sbjct: 89 VLIICPHDGTAAAAAAEAARAAGVKVISYDRLIRETDAVDYYVTFDSIAVGAQQAQYLVD 148 Query: 143 IV-PQGN-YFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGD-------------- 186 GN +L G+ DNNA LF G KVL+P + G + Sbjct: 149 HASGTGNPLYLYAGAASDNNAFLFFEGAWKVLQPKIADGTFVIKNSSEAVALQNKLDLTR 208 Query: 187 --------QWVDGWLPENALKIMENALTA----NNNKIDAVVASNDATAGGAIQALSAQG 234 Q W A + E LTA + K+ ++A ND TA A +A Sbjct: 209 DEMAKIIGQVTTNWDFNTAKNLAEANLTAATAADKGKV-YILAPNDGTARAIADAFAADK 267 Query: 235 LSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLN 294 + ++GQDA+ A ++ I G Q+MTV+K + L A + AV L Q+P+A T N Sbjct: 268 DVTEYFVTGQDAEKASVQYIIDGRQSMTVFKDVRTLVQDAIKAAVALLQDQQPEARGTYN 327 Query: 295 NGLKDVPSRLLTPIDVNKNNIKDTVIKDGFHKESEL 330 NG KDVP+ + V ++N++ +I G++ S+ Sbjct: 328 NGKKDVPAIQSPVVTVTRDNVRAALIDSGYYSASDF 363 >4RS3-A nrPDB Length = 327 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 78/305 (25%), Positives = 144/305 (47%), Gaps = 23/305 (7%) Query: 18 NVAAHAKEVKIGMAIDDLR--LERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIE 75 + AA++ +IG+ + D+ + ++ D + A++ ++ SAN + TQ SQ++ Sbjct: 5 DTAANSDTKRIGVTVYDMSSFITEGKEGMDTY---AKANNIELVWNSANNDVSTQASQVD 61 Query: 76 NMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGEL 135 ++IN+GVD ++++P L V AK +GI +LA + + D+ + D+ G Sbjct: 62 SLINQGVDAIIVVPVQADSLGPQVASAKSKGIPLLAVNAALETPDLAGNVQPDDVAAGAQ 121 Query: 136 QAKALVD-IVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLP 194 + + + D + +GN ++ G + G +VL Y D IKV+ + W Sbjct: 122 EMQMMADRLGGKGNIVILQGPLGGSGEINRGKGIDQVLAKYPD---IKVLAKDTAN-WKR 177 Query: 195 ENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRI 254 + A+ M+N +++ +ID VVA ND GA+QAL G +G V I G D G+ + Sbjct: 178 DEAVNKMKNWISSFGPQIDGVVAQNDDMGLGALQALKEAGRTG-VPIVGIDGIEDGLNAV 236 Query: 255 AAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNN 314 +G T + T+ + +A L G++ K D P ++ I K+N Sbjct: 237 KSGDFIGTSLQNGTVELSAGLAVADALVKGEDVKTD----------PVYVMPAI--TKDN 284 Query: 315 IKDTV 319 + + Sbjct: 285 VDVAI 289 >4RSM-A nrPDB Length = 327 Score = 216 bits (550), Expect = 1e-56, Method: Composition-based stats. Identities = 79/306 (25%), Positives = 146/306 (47%), Gaps = 25/306 (8%) Query: 18 NVAAHAKEVKIGMAIDDLR--LERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIE 75 + AA++ +IG+ + D+ + ++ D + A+ ++ SAN + TQ SQ++ Sbjct: 5 DPAANSDTTRIGVTVYDMSSFITAGKEGMDAY---AKDNNIELIWNSANLDVSTQASQVD 61 Query: 76 NMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGEL 135 +MIN+GVD ++++P L+ V AK +GI ++ + ++ DI + D+ G Sbjct: 62 SMINQGVDAIIVVPVQADSLAPQVASAKAKGIPLVPVNAALDSKDIAGNVQPDDVAAGAQ 121 Query: 136 QAKALVD-IVPQGNYFLMGGSPVDNNAKLFRA-GQMKVLKPYVDSGKIKVVGDQWVDGWL 193 + + + D + +GN ++ G P+ + +L R+ G +VL Y D IKV+ + W Sbjct: 122 EMQMMADRLGGKGNIVILQG-PLGQSGELDRSKGIEQVLAKYPD---IKVLAKDTAN-WK 176 Query: 194 PENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKR 253 + A+ M+N ++ +ID VVA ND GA+QAL G +G V I G D G+ Sbjct: 177 RDEAVNKMKNWISGFGPQIDGVVAQNDDMGLGALQALKESGRTG-VPIVGIDGIEDGLNA 235 Query: 254 IAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKN 313 + +G T + T+ +A L G+ + P ++ I K+ Sbjct: 236 VKSGDFIGTSLQNGTVELAAGLAVANRLAKGEPVNKE----------PVYIMPAI--TKD 283 Query: 314 NIKDTV 319 N+ + Sbjct: 284 NVDVAI 289 >4ZJP-A nrPDB Length = 292 Score = 215 bits (547), Expect = 2e-56, Method: Composition-based stats. Identities = 69/273 (25%), Positives = 123/273 (45%), Gaps = 7/273 (2%) Query: 18 NVAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENM 77 N+ + + I + + L + +D KKA LG K+ V + + ++S +E++ Sbjct: 17 NLYFQSMQETIALTVSTLDNPFFVSLKDGAQKKATELGYKLVVLDSQNDPSKELSNVEDL 76 Query: 78 INRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQA 137 RG VL+I P + +SN V A + I V+ DR ++ +I+ DN G++ Sbjct: 77 TVRGAKVLLINPTDSAAVSNAVAIANRNKIPVITLDRGAAKGEVVSHIASDNVAGGKMAG 136 Query: 138 KALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENA 197 + + G + +A R + K +++ K V+ Q D + Sbjct: 137 DFIAQKLGDGAKVIQLEGLAGTSAARERG---EGFKQAIEAHKFDVLASQPAD-FDRTKG 192 Query: 198 LKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAG 257 L + EN L A+ + A+ A ND A GA++A+SA G KV + G D G+K + +G Sbjct: 193 LNVTENLL-ASKGSVQAIFAQNDEMALGALRAISAAGK--KVLVVGFDGTEDGVKAVKSG 249 Query: 258 TQTMTVYKPITLLANTAAEIAVELGNGQEPKAD 290 TV + L+ + E A ++ G++ A Sbjct: 250 KLAATVAQQPELIGSLGVETADKILKGEKVDAK 282 >1DBP-A nrPDB Length = 271 Score = 206 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 64/264 (24%), Positives = 116/264 (43%), Gaps = 6/264 (2%) Query: 27 KIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLV 86 I + + L + +D K+A+ LG + V + N +++ ++++ RG +L+ Sbjct: 3 TIALVVSTLNNPFFVSLKDGAQKEADKLGYNLVVLDSQNNPAKELANVQDLTVRGTKILL 62 Query: 87 IIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQ 146 I P + + N VK A Q I V+ DR ++ +I+ DN G++ + + Sbjct: 63 INPTDSDAVDNAVKMANQANIPVITLDRQATKGEVVSHIASDNVLGGKIAGDYIAKKAGE 122 Query: 147 GNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALT 206 G + +A R + + V + K V+ Q D + L +M+N LT Sbjct: 123 GAKVIELQGIAGTSAARERG---EGFQQAVAAHKFNVLASQPAD-FDRIKGLNVMQNLLT 178 Query: 207 ANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKP 266 A+ + + AV A ND A GA++AL G S V + G D G K + G T+ + Sbjct: 179 AHPD-VQAVFAQNDEMALGALRALQTAGKS-DVMVVGFDGTPDGEKAVNDGKLAATIAQL 236 Query: 267 ITLLANTAAEIAVELGNGQEPKAD 290 + E A ++ G++ +A Sbjct: 237 PDQIGAKGVETADKVLKGEKVQAK 260 >1GUD-A nrPDB Length = 288 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 64/272 (23%), Positives = 117/272 (43%), Gaps = 16/272 (5%) Query: 29 GMAIDDLRLERWQKDRDIFVKKAESLGAKV--FVQSANGNEETQMSQIENMINRGVDVLV 86 + + L W + +A++LG V F + G+ ++Q+ E++ N+ + Sbjct: 5 AVVLKTLSNPFWVDMKKGIEDEAKTLGVSVDIFASPSEGDFQSQLQLFEDLSNKNYKGIA 64 Query: 87 IIPYNGQVLSNVVKEAKQEGIKVLAYDRMIN-------DADIDFYISFDNEKVGELQAKA 139 P + L V A ++GI ++ D I+ +++ +++ DN VG A Sbjct: 65 FAPLSSVNLVMPVARAWKKGIYLVNLDEKIDMDNLKKAGGNVEAFVTTDNVAVGAKGASF 124 Query: 140 LVDIVPQ--GNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENA 197 ++D + G ++ G + + + R G + K + +IK+V Q D W A Sbjct: 125 IIDKLGAEGGEVAIIEGKAGNASGEARRNGATEAFK---KASQIKLVASQPAD-WDRIKA 180 Query: 198 LKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAG 257 L + N L N N I A+ +ND A G QA++ G +GKV + G D K + AG Sbjct: 181 LDVATNVLQRNPN-IKAIYCANDTMAMGVAQAVANAGKTGKVLVVGTDGIPEARKMVEAG 239 Query: 258 TQTMTVYKPITLLANTAAEIAVELGNGQEPKA 289 T TV + + T ++ V+ + Sbjct: 240 QMTATVAQNPADIGATGLKLMVDAEKSGKVIP 271 >5DTE-A nrPDB Length = 311 Score = 183 bits (464), Expect = 1e-46, Method: Composition-based stats. Identities = 77/274 (28%), Positives = 130/274 (47%), Gaps = 14/274 (5%) Query: 23 AKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQ--MSQIENMINR 80 A + +I + + L E + R + A+ + VQ A + T+ + +ENMI + Sbjct: 24 ADKPQIALLMKTLSNEYFISMRQGAEETAKQKDIDLIVQVAEKEDSTEQLVGLVENMIAK 83 Query: 81 GVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDF------YISFDNEKVGE 134 VD +++ P + ++A++ GI ++ D ++ + Y+ DN G Sbjct: 84 KVDAIIVTPNDSIAFIPAFQKAEKAGIPIIDLDVRLDAKAAEAAGLKFNYVGVDNFNGGY 143 Query: 135 LQAKALVDIVPQ-GNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWL 193 L+AK L + + + GN ++ G P +N + + G +K Y D IK+V Q + W Sbjct: 144 LEAKNLAEAIGKKGNVAILEGIPGVDNGEQRKGGALKAFAEYPD---IKIVASQSAN-WE 199 Query: 194 PENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKR 253 E AL + N LTAN N I+ + A+ND A GA+ A+ GL+GKV +SG D I+ Sbjct: 200 TEQALNVTTNILTANPN-INGIFAANDNMAIGAVTAVENAGLAGKVLVSGYDGIPLAIEY 258 Query: 254 IAAGTQTMTVYKPITLLANTAAEIAVELGNGQEP 287 + G T+ + A E A++ N QE Sbjct: 259 VKQGKMQNTIDQLPKKQVAIAIEHALKQINKQEI 292 >4WZZ-A nrPDB Length = 371 Score = 180 bits (457), Expect = 6e-46, Method: Composition-based stats. Identities = 67/275 (24%), Positives = 116/275 (42%), Gaps = 19/275 (6%) Query: 21 AHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSA-NGNEETQMSQIENMIN 79 +A + + QK+ + + + E+ G K +Q + E Q++ I N I+ Sbjct: 50 GYATTATYAIIVKSAGNPYNQKESEGYKQVIEANGGKCVIQEPKSATAEDQITCINNAIS 109 Query: 80 RGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKA 139 +GVD + I + L + EAK +GI VL+ D N ++ N+ A+A Sbjct: 110 QGVDCIAIAANDTDALEPALTEAKNQGIHVLSLDSATNANSRKVFV---NQAGTTQIAQA 166 Query: 140 LVDI-----VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLP 194 L+D G++ ++ + N + G MK + K+ ++G + D Sbjct: 167 LMDAILDISGGSGDWAVLSAASTATNQNAWIDG-MKTVMQDSKYSKLNLIGVYYGDDEY- 224 Query: 195 ENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISG-----QDADLA 249 + + E L A+ N I + A A + L +GLSGKV ++G + AD Sbjct: 225 QASCDQTEAILAADPN-IKVICAPTTVGIMAAAKVLQDKGLSGKVKLTGLGLPSEMADYI 283 Query: 250 GIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNG 284 G + M ++ PI L N AA ++ L NG Sbjct: 284 GDDDQHS-CPYMFLWNPIQ-LGNLAAYASISLVNG 316 >5OCP-A nrPDB Length = 302 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 67/261 (25%), Positives = 107/261 (40%), Gaps = 14/261 (5%) Query: 44 RDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAK 103 + +A+ G + A +E Q+ + + I +GVD ++I P V+KEAK Sbjct: 19 SEAVKAEAKQRGIDLKFADAQQKQENQIKAVRSFIAQGVDAIIIAPVVETGWKPVLKEAK 78 Query: 104 QEGIKVLAYDRMINDADIDFY---ISFDNEKVGELQAKALVDIVPQGNYFL--MGGSPVD 158 + I V+ DR I D + I+ D + G + L+D QGN + + G+ Sbjct: 79 RAKIPVVIVDRNIKVDDDSLFLTRIASDFSEEGRKIGQWLMDK-TQGNCDIAELQGTVGA 137 Query: 159 NNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNK-IDAVVA 217 A AG +V+ Y ++ K+V Q + ++ME L A N + + AV + Sbjct: 138 TAAIDRAAGFNQVIANYPNA---KIVRSQTG-EFTRAKGKEVMEGFLKAQNGQPLCAVWS 193 Query: 218 SNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAA 275 ND A GA+QA+ GL + I D K +A G TV L A Sbjct: 194 HNDEMALGAVQAIKEAGLKPGKDILIVSVDGVPDYFKAMADGDVNATVELSP-YLGGPAF 252 Query: 276 EIAVELGNGQEPKADTTLNNG 296 + G + +A G Sbjct: 253 DAIDAYLKGNKDQAKLISTTG 273 >2IPN-A nrPDB Length = 318 Score = 167 bits (423), Expect = 6e-42, Method: Composition-based stats. Identities = 65/310 (20%), Positives = 133/310 (42%), Gaps = 27/310 (8%) Query: 25 EVKIGMAIDDLRLERWQKDRDIFVKKAESL-GAKVFVQSANGNEETQMSQIENMINRGVD 83 + +IG+ I R + A++ ++ + + ++ Q QI+ ++ +GV Sbjct: 3 DTRIGVTIYKYDDCFMSVVRKAIEQDAKAAPDVQLLMNDSQNDQSKQNDQIDVLLAKGVK 62 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYD-----RMINDADIDFYISFDNEKVGELQAK 138 L I + V+++A+ + + V+ ++ + ++ D +Y+ D+++ G +Q Sbjct: 63 ALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGIIQGD 122 Query: 139 ALV---------DIVPQGNY--FLMGGSPVDNNAKLFRAGQMKVLKPY-VDSGKIKVVGD 186 + D+ G L+ G P +A+ +K L + + ++++ Sbjct: 123 LIAKHWAANQGWDLNKDGQIQFVLLKGEPGHPDAEARTTYVIKELNDKGIKTEQLQL--- 179 Query: 187 QWVDGWLPENALKIMENALT-ANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQD 245 W A M+ L+ N NKI+ V+A+ND A GA++AL A S + + G D Sbjct: 180 -DTAMWDTAQAKDKMDAWLSGPNANKIEVVIANNDCMAMGAVEALKAHNKSS-IPVFGVD 237 Query: 246 ADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLL 305 A + + +G TV A ++A L +G+ AD T N D + Sbjct: 238 ALPEALALVKSGALAGTVLNDANNQAKATFDLAKNLADGKGA-ADGT--NWKIDNKVVRV 294 Query: 306 TPIDVNKNNI 315 + V+K+N+ Sbjct: 295 PYVGVDKDNL 304 >2VK2-A nrPDB Length = 306 Score = 167 bits (422), Expect = 7e-42, Method: Composition-based stats. Identities = 68/260 (26%), Positives = 109/260 (41%), Gaps = 20/260 (7%) Query: 43 DRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA 102 + ++ +AE G + + +E Q+ + + + +GVD + I P V+KEA Sbjct: 20 ETNVAKSEAEKRGITLKIADGQQKQENQIKAVRSFVAQGVDAIFIAPVVATGWEPVLKEA 79 Query: 103 KQEGIKVLAYDRMINDADIDFY---ISFDNEKVGELQAKALVDI--VPQGNYFLMGGSPV 157 K I V DR I+ D Y ++ DN G+L LV N + G+ Sbjct: 80 KDAEIPVFLLDRSIDVKDKSLYMTTVTADNILEGKLIGDWLVKEVNGKPCNVVELQGTVG 139 Query: 158 DNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNN--KIDAV 215 + A + G + +K ++ IK++ Q D + ++ME+ + A NN I V Sbjct: 140 ASVAIDRKKGFAEAIK---NAPNIKIIRSQSGD-FTRSKGKEVMESFIKAENNGKNICMV 195 Query: 216 VASNDATAGGAIQALSAQGL-SGKVAISG-QDADLAGIKRIAAGTQTMTVYKPITLLANT 273 A ND GAIQA+ GL GK ++G D K + G +V L N Sbjct: 196 YAHNDDMVIGAIQAIKEAGLKPGKDILTGSIDGVPDIYKAMMDGEANASV----ELTPNM 251 Query: 274 AAEIAVELGNGQEPKADTTL 293 A L ++ K D T+ Sbjct: 252 AGPAFDAL---EKYKKDGTM 268 >1GCG-A nrPDB Length = 309 Score = 166 bits (420), Expect = 1e-41, Method: Composition-based stats. Identities = 64/313 (20%), Positives = 128/313 (40%), Gaps = 33/313 (10%) Query: 25 EVKIGMAIDDLRLERWQKDRDIFVKKAESLG-----AKVFVQSANGNEETQMSQIENMIN 79 + +IG+ I + K E G ++ + + ++ Q QI+ ++ Sbjct: 2 DTRIGVTIYKYDDNF----MSVVRKAIEKDGKSAPDVQLLMNDSQNDQSKQNDQIDVLLA 57 Query: 80 RGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYD-----RMINDADIDFYISFDNEKVGE 134 +GV L I + V+++A+ + + V+ ++ + ++ D +Y+ D+++ G Sbjct: 58 KGVKALAINLVDPAAAGTVIEKARGQNVPVVFFNKEPSRKALDSYDKAYYVGTDSKESGV 117 Query: 135 LQAKALVD-----------IVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKV 183 +Q + + Y L+ G P +A+ +K L + + Sbjct: 118 IQGDLIAKHWQANQGWDLNKDGKIQYVLLKGEPGHPDAEARTTYVVKELND--KGIQTEQ 175 Query: 184 VGDQWVDGWLPENALKIMENALT-ANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAIS 242 + W A M+ L+ N NKI+ V+A+NDA A GA++AL A S + + Sbjct: 176 LALDTA-MWDTAQAKDKMDAWLSGPNANKIEVVIANNDAMAMGAVEALKAHNKSS-IPVF 233 Query: 243 GQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPS 302 G DA + + +G TV A ++A L G+ AD T + + Sbjct: 234 GVDALPEALALVKSGAMAGTVLNDANNQAKATFDLAKNLAEGKGA-ADGT--SWKIENKI 290 Query: 303 RLLTPIDVNKNNI 315 + + V+K+N+ Sbjct: 291 VRVPYVGVDKDNL 303 >4WUT-A nrPDB Length = 313 Score = 160 bits (404), Expect = 9e-40, Method: Composition-based stats. Identities = 66/305 (21%), Positives = 126/305 (41%), Gaps = 24/305 (7%) Query: 28 IGMAIDDLRLERWQ---KDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDV 84 I + + + WQ K D + K ++ +A Q++ +EN +NR VD Sbjct: 26 IAVIVKTVNSTFWQNVQKGADAAIGKQKAHTITFQGPAAESAIADQVNMVENAVNRKVDA 85 Query: 85 LVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISF---DNEKVGELQAKALV 141 +++ P + L VK+A + I V+ D M++ +Y +F DN+ GEL AKA++ Sbjct: 86 ILLAPSDPDALVPAVKKAWEARIPVVIIDSMLSKDAEKYYQAFLATDNKAAGELAAKAMI 145 Query: 142 DIVP-QGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKI 200 V +G +M + G +K + K+++VG + + AL Sbjct: 146 QKVGTEGKIAVMSYVAGAGSEIGRVGGFTDYIK---ANSKLQIVGPYYSQSQMA-TALNQ 201 Query: 201 MENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQT 260 + L AN + + + +N+ TA G +A+ G +GK+ G D + + + GT Sbjct: 202 TTDVLAANAD-LKGIFGANEPTAIGMGRAIKQAGKAGKLVAIGFDGNQDLQEFVKDGTLE 260 Query: 261 MTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTPIDVNKNNIKDTVI 320 TV + + + ++L + ++ + + V K NI Sbjct: 261 ATVVQGSYQMGEKGVDTLLKLLSKEKVEK------------FIDTGVVVVTKQNIDKPEA 308 Query: 321 KDGFH 325 K+ + Sbjct: 309 KNVLY 313 >5BRA-A nrPDB Length = 350 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 63/296 (21%), Positives = 123/296 (41%), Gaps = 17/296 (5%) Query: 19 VAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKV-FVQSANGNEETQMSQIENM 77 A+ K+ I + + + + RD + G V V + + Q+ +EN+ Sbjct: 38 TTANDKKYTIATVVKVDGIAWFDRMRDGVDQFKADTGNDVWMVGPSQADAAAQVQIVENL 97 Query: 78 INRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYI-SFDNEKVGELQ 136 I +GVD + I+P++ + + V+K+A++ GI V++++ N ++D+ I +FDN+ G Sbjct: 98 IAQGVDAIAIVPFSVEAVEPVLKKARERGIVVISHEAS-NIQNVDYDIEAFDNKAYGANL 156 Query: 137 AKAL-VDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYV-----DSGKIKVVGDQWVD 190 K L + +G Y GS + + G ++ K +G+++ D D Sbjct: 157 MKELGKSMGGKGKYVTTVGSLTSKSQMEWIDGAVEYQKANFPEMSEATGRLETYDDANTD 216 Query: 191 GWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAG 250 ++ A+TA + I ++ + T+ GA + ++ GL GKV +G Sbjct: 217 Y-------NKLKEAMTAYPD-ITGILGAPMPTSAGAGRLIAEGGLKGKVFFAGTGLVSVA 268 Query: 251 IKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLT 306 + I + + +AV + + LN GL S L Sbjct: 269 GEYIKNDDVQYIQFWDPAVAGYAMNMLAVAALEKKNDQIKAGLNLGLPGYESLLAP 324 >3D02-A nrPDB Length = 303 Score = 112 bits (280), Expect = 2e-25, Method: Composition-based stats. Identities = 62/268 (23%), Positives = 102/268 (38%), Gaps = 16/268 (5%) Query: 60 VQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDA 119 V ++ + Q+ IE++I R VD + I+P + VL V K+A+ GI VL + Sbjct: 40 VGPSSTDAPQQVKIIEDLIARKVDAITIVPNDANVLEPVFKKARDAGIVVLT-NESPGQP 98 Query: 120 DIDFYIS-FDNEKVGELQAKALVD-IVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKP-YV 176 ++ + DNEK + + + +G Y + GS L+ +K K Y Sbjct: 99 SANWDVEIIDNEKFAAEYVEHMAKRMGGKGGYVIYVGSLTVPQHNLWADLLVKYQKEHYP 158 Query: 177 DSGKIKVVGD-QWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGL 235 D ++ L +M+ + AVV+ GA +A+ + Sbjct: 159 DMHEVTRRMPVAESVDDSRRTTLDLMKTY-----PDLKAVVSFGSNGPIGAGRAVKEKRA 213 Query: 236 SGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNN 295 KVA+ G I +G T + A +A L NG+ + L Sbjct: 214 KNKVAVYGMMIPSQAASLIKSGDITEGITYDPATAGYALAAVASTLLNGKTIEPGFELKE 273 Query: 296 -GLKDVPS-----RLLTPIDVNKNNIKD 317 G +V S R + VNK+NI Sbjct: 274 LGKAEVDSDKHIIRFHKVLLVNKDNIDS 301 >4PZ0-A nrPDB Length = 324 Score = 104 bits (258), Expect = 8e-23, Method: Composition-based stats. Identities = 50/248 (20%), Positives = 96/248 (38%), Gaps = 8/248 (3%) Query: 45 DIFVKKAESLGAKVFV-QSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAK 103 + + + LG +V + + Q+ I N IN+ D L++ + LS ++ AK Sbjct: 30 EGAKEMGDKLGVQVKYDGPSEASVSGQVKYINNFINQNYDALMVSSTSVDGLSQSLQRAK 89 Query: 104 QEGIKVLAYDRMINDADIDFYI--SFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNNA 161 ++G+ VL +D +N D FYI ++ L I +G SP + Sbjct: 90 KKGMTVLTWDSDVNPKDRSFYISQGTPDQLANLLIEMTSKQIGDKGKVAFFYSSPTVTDQ 149 Query: 162 KLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDA 221 + +++K ++V Q+ + + +L + EN L + I+AV+ + Sbjct: 150 NQWVTKAKEIIKE--KYPNWEIVTTQYGEN-NAQKSLSVGENILKTYPD-INAVICPDAT 205 Query: 222 TAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVEL 281 QA + KV ++G + GT + A +A E+ Sbjct: 206 ALPAMAQAAENLKMDKKVVVTGFSTPNVMRDYVKRGTVQQFGLWDVKQQGALATYVANEI 265 Query: 282 -GNGQEPK 288 G++ K Sbjct: 266 VVKGKKLK 273 >5BQ3-A nrPDB Length = 332 Score = 92.9 bits (229), Expect = 1e-19, Method: Composition-based stats. Identities = 47/268 (17%), Positives = 97/268 (36%), Gaps = 12/268 (4%) Query: 59 FVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMIND 118 V + +Q+S I + + G +VLVI + + +++A++ G KV+ +D Sbjct: 63 VVGPLEASSSSQVSFINSEVQAGTNVLVIAANDPDAVCPALQDARKAGTKVVTFDSDSAA 122 Query: 119 ADIDFYIS-FDNEKVGELQAKALVDI-VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYV 176 D +I+ ++++V + D G ++ + N + + Sbjct: 123 DCRDLFINQVESKQVAITMLDMVSDQIGGSGKVAILSATANAANQNAWIKFMEDEIASND 182 Query: 177 DSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLS 236 I++V + D + + + L A+ + ++A+V+ + LS Sbjct: 183 KYKGIEIVAKVYGDD-DDTKSFQEAQGLLQAHPD-LNAIVSPTTVGIAATARYLSTSDYK 240 Query: 237 GKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVEL----GNGQEPKADTT 292 GKV ++G + GT L AA L G+ + T Sbjct: 241 GKVFLTGLGLPNEMRSFVKDGTVKEFALWDPAQLGYVAAYAGAALDSGAIKGEVGEKFTA 300 Query: 293 LNNGLKDV----PSRLLTPIDVNKNNIK 316 N G + + + P+ N +NI Sbjct: 301 GNLGERTIGENKTVVVGDPVRFNADNID 328 >4KVF-A nrPDB Length = 342 Score = 91.0 bits (224), Expect = 6e-19, Method: Composition-based stats. Identities = 49/246 (19%), Positives = 94/246 (38%), Gaps = 5/246 (2%) Query: 48 VKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGI 107 V E G V + + +Q+S I +I + DV+V+ + + + +A++ I Sbjct: 63 VAVGEIKGEYKLVGPNDASASSQVSYINTLIQQQQDVIVVAANDPNAVCPSLNQARKADI 122 Query: 108 KVLAYDRMINDADIDFYISFDNEKV-GELQAKALVDI-VPQGNYFLMGGSPVDNNAKLFR 165 KV+ +D D +I+ + GE K ++ G ++ +P N + Sbjct: 123 KVVTFDSDAAKTCRDAFINQATTQGIGESLVKMAKELAGGSGEIAVLSATPNATNQNSWI 182 Query: 166 AGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGG 225 MK ++ K+K+V + + + + + L + N + +V+ Sbjct: 183 -EVMKTELAKPENAKLKLVKIAYGND-DDQKSFTEAQGLLQSYPN-LKVIVSPTTVGIAA 239 Query: 226 AIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQ 285 A + +SA GKVAI+G + + GT + AA L +GQ Sbjct: 240 ASRYVSASSYKGKVAITGLGLPNQMRQYVKDGTVKKFALWNPADIGYLAAYAGAALKSGQ 299 Query: 286 EPKADT 291 A Sbjct: 300 ITGAQG 305 >3EJW-A nrPDB Length = 315 Score = 87.2 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 54/272 (19%), Positives = 96/272 (35%), Gaps = 19/272 (6%) Query: 48 VKKAESLGAKVFV-QSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEG 106 VK E +GAKV + Q+ I N +N+G + L++ + L +K A + G Sbjct: 24 VKAGEEVGAKVTYDGPTEPSVSGQVQFINNFVNQGYNALIVSSVSPDGLCPALKRAMERG 83 Query: 107 IKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQG------NYFLMGGSPVDNN 160 + V+ +D +N +YI N+ E LVD+ +G SP + Sbjct: 84 VLVMTWDSDVNPDCRSYYI---NQGTPEQLGGLLVDMAAEGVKKEKAKVAFFYSSPTVTD 140 Query: 161 AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASND 220 + + ++V Q+ + +L+ E+ L + +DA++A + Sbjct: 141 QNAWAEAAKAKIAKE--HPGWEIVTTQYGYN-DAQKSLQTAESILQTYPD-LDAIIAPDA 196 Query: 221 ATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVE 280 A QA + V I G I GT +T + +A Sbjct: 197 NALPAAAQAAENLKRAEGVTIVGFSTPNVMRPYIERGTIQRFGLWDVTQQGKISVFVADH 256 Query: 281 LGNGQEPKADTTLNNGLKDVPSRLLTPIDVNK 312 + K L ++P + NK Sbjct: 257 VLKNGPMKVGEKL-----EIPGVGTVEVSANK 283 >1TM2-A nrPDB Length = 316 Score = 86.8 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 42/246 (17%), Positives = 85/246 (34%), Gaps = 15/246 (6%) Query: 45 DIFVKKAESLGAKVFV-QSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAK 103 + + ++LG V + Q+ + N +N+G D +++ + L +K A Sbjct: 23 NGAQEAGKALGIDVTYDGPTEPSVSGQVQLVNNFVNQGYDAIIVSAVSPDGLCPALKRAM 82 Query: 104 QEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVP------QGNYFLMGGSPV 157 Q G+K+L +D +YI N+ + LV++ + SP Sbjct: 83 QRGVKILTWDSDTKPECRSYYI---NQGTPKQLGSMLVEMAAHQVDKEKAKVAFFYSSPT 139 Query: 158 DNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVA 217 + + + + ++V Q+ +L+ E + A + +DA++A Sbjct: 140 VTDQNQWVKEAKAKISQ--EHPGWEIVTTQFGYN-DATKSLQTAEGIIKAYPD-LDAIIA 195 Query: 218 SNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEI 277 DA A A + +AI G + GT + + + Sbjct: 196 P-DANALPAAAQAAENLKRNNLAIVGFSTPNVMRPYVQRGTVKEFGLWDVVQQGKISVYV 254 Query: 278 AVELGN 283 A L Sbjct: 255 ANALLK 260 >3T95-A nrPDB Length = 335 Score = 85.6 bits (210), Expect = 3e-17, Method: Composition-based stats. Identities = 56/273 (20%), Positives = 97/273 (35%), Gaps = 22/273 (8%) Query: 48 VKKAESLGAKVFV-QSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEG 106 V ++LG V + Q+ I N +N+G + +V+ + L +K A Q G Sbjct: 45 VDAGKALGVDVTYDGPTEPSVSGQVQLINNFVNQGYNAIVVSAVSPDGLCPALKRAMQRG 104 Query: 107 IKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVP------QGNYFLMGGSPVDNN 160 +K+L +D YI N+ LVD+ Q SP + Sbjct: 105 VKILTWDSDTKPECRSVYI---NQGTPNQLGSMLVDMAANQVKKEQAKVAFFYSSPTVTD 161 Query: 161 AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASND 220 + K ++ + ++V Q+ +L+ E L A + +DA++A D Sbjct: 162 QNQWVNEAKKKIQQ--EHPGWEIVTTQFGYN-DATKSLQTAEGILKAYAD-LDAIIAP-D 216 Query: 221 ATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVE 280 A A A + VAI G + GT + + +A E Sbjct: 217 ANALPAAAQAAENLKRANVAIVGFSTPNVMRPYVERGTVKEFGLWDVVNQGKISVYVANE 276 Query: 281 LGNGQEPKADTTLNNGLK-DVPSRLLTPIDVNK 312 + LN G K D+P+ + + N+ Sbjct: 277 MLK------KGDLNVGDKIDIPNIGVVEVSPNR 303 >3EDC-A nrPDB Length = 360 Score = 77.5 bits (189), Expect = 7e-15, Method: Composition-based stats. Identities = 65/278 (23%), Positives = 113/278 (40%), Gaps = 20/278 (7%) Query: 21 AHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGN-EETQMSQIENMIN 79 A + + IG+A L L + +A+ LGA V V + E + + N++ Sbjct: 57 AGKQSLLIGVATSSLALHAPSQIVAAIKSRADQLGASVVVSMVERSGVEACKAAVHNLLA 116 Query: 80 RGVDVLVII-PYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAK 138 + V L+I P + Q V EA + L D ++D I F +E L + Sbjct: 117 QRVSGLIINYPLDDQDAIAV--EAACTNVPALFLD--VSDQTPINSIIFSHEDGTRLGVE 172 Query: 139 ALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENAL 198 LV + L+ G +A+L AG K L +I+ + ++ D W + Sbjct: 173 HLV-ALGHQQIALLAGPLSSVSARLRLAGWHKYLTR----NQIQPIAEREGD-WSAMSGF 226 Query: 199 KIMENALTANNNKI-DAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIA 255 + L N + A++ +ND A GA++A++ GL +++ G D I Sbjct: 227 QQTMQML--NEGIVPTAMLVANDQMALGAMRAITESGLRVGADISVVGYDDTEDSSCYI- 283 Query: 256 AGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTL 293 T+ + LL T+ + ++L GQ K + L Sbjct: 284 --PPLTTIKQDFRLLGQTSVDRLLQLSQGQAVKGNQLL 319 >3OQN-A nrPDB Length = 339 Score = 74.8 bits (182), Expect = 5e-14, Method: Composition-based stats. Identities = 50/270 (18%), Positives = 105/270 (38%), Gaps = 12/270 (4%) Query: 21 AHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINR 80 A K +G+ I D+ + + A + + +++ N E ++ + M+ + Sbjct: 56 ASKKTTTVGVIIPDISSIFYSELARGIEDIATMYKYNIILSNSDQNMEKELHLLNTMLGK 115 Query: 81 GVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKAL 140 VD +V G + V E K+ + ++ + + + ++ D E+ K L Sbjct: 116 QVDGIVF--MGGNITDEHVAEFKRSPVPIV-LAASVEEQEETPSVAIDYEQAIYDAVKLL 172 Query: 141 VDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKI 200 VD F+ G N G + L+ + V + + ++ L+ Sbjct: 173 VDKGHTDIAFVSGPMAEPINRSKKLQGYKRALEEANLPFNEQFVAE---GDYTYDSGLEA 229 Query: 201 MENALTANNNKIDAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAGT 258 +++ ++ + K A++++ D A G I A QGLS + I G D + + Sbjct: 230 LQHLMSLDK-KPTAILSATDEMALGIIHAAQDQGLSIPEDLDIIGFDNTRLSL-MVRP-- 285 Query: 259 QTMTVYKPITLLANTAAEIAVELGNGQEPK 288 Q TV +P + A + +L N + + Sbjct: 286 QLSTVVQPTYDIGAVAMRLLTKLMNKEPVE 315 >1RZR-D nrPDB Length = 332 Score = 72.5 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 47/271 (17%), Positives = 103/271 (38%), Gaps = 12/271 (4%) Query: 21 AHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINR 80 A K +G+ I D+ + + A + + +++ N++ ++ + NM+ + Sbjct: 56 ASKKTTTVGVIIPDISNIFYAELARGIEDIATMYKYNIILSNSDQNQDKELHLLNNMLGK 115 Query: 81 GVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKAL 140 VD ++ +G V V+E K+ + V+ I + ++ D E+ ++L Sbjct: 116 QVDGIIF--MSGNVTEEHVEELKKSPVPVV-LAASIESTNQIPSVTIDYEQAAFDAVQSL 172 Query: 141 VDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKI 200 +D + N + G+ + + A ++K K + + V V+G ++ Sbjct: 173 IDSGHK-NIAFVSGTLEEP---INHAKKVKGYKRALTESGLPVRDSYIVEGDYTYDSGIE 228 Query: 201 MENALTANNNKIDAVVASNDATAGGAIQALSAQGL--SGKVAISGQDADLAGIKRIAAGT 258 L + K A+ D A G I +GL + I G D + Sbjct: 229 AVEKLLEEDEKPTAIFVGTDEMALGVIHGAQDRGLNVPNDLEIIGFDNTRLS-TMVRP-- 285 Query: 259 QTMTVYKPITLLANTAAEIAVELGNGQEPKA 289 Q +V +P+ + A + + N + + Sbjct: 286 QLTSVVQPMYDIGAVAMRLLTKYMNKETVDS 316 >2IKS-A nrPDB Length = 293 Score = 72.1 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 44/271 (16%), Positives = 94/271 (34%), Gaps = 13/271 (4%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 + IG+ I DL + + + ++A G ++ + + + +M IE+++ R VD Sbjct: 19 RTRSIGLVIPDLENTSYTRIANYLERQARQRGYQLLIACSEDQPDNEMRCIEHLLQRQVD 78 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 +++ + + ++A DR ++ + D + E+ A+ L Sbjct: 79 AIIVSTSLPPE-HPFYQRWANDPFPIVALDRALDREHFTSVVGADQDDA-EMLAEEL-RK 135 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 P +G P + + L G K + + + E A ++ E Sbjct: 136 FPAETVLYLGALPELSVSFLREQGFRTAWKDDPREVHF-----LYANSYEREAAAQLFEK 190 Query: 204 ALTANNNKIDAVVASNDATAGGAIQA-LSAQGLSGKVAISGQDADLAGIKRIAAGTQTMT 262 L + A+ ++ A G + L G D + + + Sbjct: 191 WLETHPMP-QALFTTSFALLQGVMDVTLRRDGKLPSDLAIATFGDNELLDFLQ--CPVLA 247 Query: 263 VYKPITLLANTAAEIAVE-LGNGQEPKADTT 292 V + +A EI + L ++PK T Sbjct: 248 VAQRHRDVAERVLEIVLASLDEPRKPKPGLT 278 >6BGD-A nrPDB Length = 378 Score = 72.1 bits (175), Expect = 3e-13, Method: Composition-based stats. Identities = 48/215 (22%), Positives = 81/215 (37%), Gaps = 40/215 (18%) Query: 114 RMINDADIDFYISFDNEKVGELQAKAL----------VDIVPQG--NYFLMGGSPVDNNA 161 +N D +Y+ FD + G +Q K + VD G Y L G N++ Sbjct: 33 AAMNWNDKTYYVGFDAKFGGSIQGKMILDFLASSESSVDRNGDGIIGYVLCIGDVGHNDS 92 Query: 162 KLFRAG---QMKVLKPYVDSGKIK----VVGDQW---------------VDGWLPENALK 199 K+ G + D G+ K VVG + +A + Sbjct: 93 KVRTEGIRRALGTWTGSSDPGQAKEGQAVVGGKSYKVVELEGKAMTGTDGSTANTNSATE 152 Query: 200 IMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQ 259 M + + +KID V+++ND A G +QA + I G DA+ ++ + G Sbjct: 153 SMGSWVAKFADKIDLVISNNDGMAMGCLQA---SNYPRGLPIFGYDANADAVESVGKGEL 209 Query: 260 TMTVYKPITLLANTAAEIAVELGN---GQEPKADT 291 T TV + + A +I L + G++ A+ Sbjct: 210 TGTVSQNVDAQAVAVLQIIRNLLDGSSGEDVVANG 244 >2PUG-A nrPDB Length = 340 Score = 71.8 bits (174), Expect = 4e-13, Method: Composition-based stats. Identities = 54/271 (19%), Positives = 104/271 (38%), Gaps = 15/271 (5%) Query: 25 EVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDV 84 IG+ + + + K G + + +A N E Q + + M + VD Sbjct: 58 TKSIGLLATSSEAAYFAEIIEAVEKNCFQKGYTLILGNAWNNLEKQRAYLSMMAQKRVDG 117 Query: 85 LVI-IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 L++ + L +++E + I ++ D AD + + + G + + L++ Sbjct: 118 LLVMCSEYPEPLLAMLEEYRH--IPMVVMDWGEAKADFTDAVIDNAFEGGYMAGRYLIER 175 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDG-WLPENALKIME 202 ++ G N AG MK ++ + IKV V G + PE+ + M+ Sbjct: 176 -GHREIGVIPGPLEQNTGAGRLAGFMKAMEEAM----IKVPESWIVQGDFEPESGYRAMQ 230 Query: 203 NALTANNNKIDAVVASNDATAGGAIQALSAQGL--SGKVAISGQDADLAGIKRIAAGTQT 260 L+ ++ AV D A GA+ A GL V++ G D A T Sbjct: 231 QILS-QPHRPTAVFCGGDIMAMGALCAADEMGLRVPQDVSLIGYDNVRNARYFTPALT-- 287 Query: 261 MTVYKPITLLANTAAEIAVELGNGQEPKADT 291 T+++P L TA + ++ + + + Sbjct: 288 -TIHQPKDSLGETAFNMLLDRIVNKREEPQS 317 >3CTP-A nrPDB Length = 330 Score = 67.1 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 51/266 (19%), Positives = 110/266 (41%), Gaps = 24/266 (9%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 IG+ + ++ + + + + A++ G +F+ + + ++E + + +E + + V Sbjct: 59 NSKTIGLMVPNISNPFFNQMASVIEEYAKNKGYTLFLCNTDDDKEKEKTYLEVLQSHRVA 118 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 ++ + E I V+A++ I D IS DN G + L + Sbjct: 119 GIIASRSQCE------DEYANIDIPVVAFENHI--LDNIITISSDNYNGGRMAFDHLYEK 170 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 + G V +L G + D + K + ++ + + +K++E Sbjct: 171 -GCRKILHIKGPEVFEATELRYKGFL-------DGARAKDLEIDFI-EFQHDFQVKMLEE 221 Query: 204 ALTANNNKI--DAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAGTQ 259 + + + + D + ND A ++AL +G+S +V I G D G + T Sbjct: 222 DINSMKDIVNYDGIFVFNDIAAATVMRALKKRGVSIPQEVQIIGFDNSFIGELLYPSLT- 280 Query: 260 TMTVYKPITLLANTAAEIAVELGNGQ 285 T+ +PI LA T E+ +++ NG+ Sbjct: 281 --TINQPIEALAYTIIELLIKIINGE 304 >3DBI-A nrPDB Length = 338 Score = 66.4 bits (160), Expect = 2e-11, Method: Composition-based stats. Identities = 47/263 (17%), Positives = 102/263 (38%), Gaps = 16/263 (6%) Query: 48 VKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVIIP--YNGQVLSNVVKEAKQE 105 + AE G ++ + + E + I+ +++ D ++I P + + +++ Q Sbjct: 86 ARMAEEKGRQLLLADGKHSAEEERQAIQYLLDLRCDAIMIYPRFLSVDEIDDIIDAHSQ- 144 Query: 106 GIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNNAKLFR 165 ++ +R + + D+++ L++ Q + GS + Sbjct: 145 --PIMVLNRRLRKNS-SHSVWCDHKQTSFNAVAELINAGHQ-EIAFLTGSMDSPTSIERL 200 Query: 166 AGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGG 225 AG L + + K++ + W P + + +E L K A+VASND A G Sbjct: 201 AGYKDALAQHGIALNEKLIAN---GKWTPASGAEGVEMLLERGA-KFSALVASNDDMAIG 256 Query: 226 AIQALSAQG--LSGKVAISGQDADLAGIKRIAAGTQTMTVYKPITLLANTAAEIAVELGN 283 A++AL +G + +V++ G D + A +V P+T + + + + Sbjct: 257 AMKALHERGVAVPEQVSVIGFDDIAIAPYTVPA---LSSVKIPVTEMIQEIIGRLIFMLD 313 Query: 284 GQEPKADTTLNNGLKDVPSRLLT 306 G + T + L S + Sbjct: 314 GGDFSPPKTFSGKLIRRDSLIAP 336 >6DSP-A nrPDB Length = 347 Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats. Identities = 49/261 (18%), Positives = 100/261 (38%), Gaps = 22/261 (8%) Query: 44 RDIFVKKAESLGAKVFV-QSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEA 102 K +E G KV AN + +Q+S I + +G + + + + + + +K A Sbjct: 40 NKGAQKYSEQWGFKVDYEGDANASAASQVSVINKAVQQGTNAICLSSVDAAGVKDALKAA 99 Query: 103 KQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQG-------------NY 149 G+ V +D ++ + + ++ E + LV + Y Sbjct: 100 ADAGVTVTTWDSDVDPSVRKVMV---SQGTPEQLGQMLVQMGYDSLKERGKDPEKDAIKY 156 Query: 150 FLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANN 209 + + ++ K +K + + V D + E A+ + E+ L+A++ Sbjct: 157 CWHYSNATVTDQNSWQVEGEKYIKSKYPNWQ-NVAPDNYYSNQDAEQAISVGESILSAHS 215 Query: 210 NKIDAVVASNDATAG-GAIQALSAQGLSGK-VAISGQDADLAGIKRIAAGTQTMTVYKPI 267 + ID ++ ND+TA G QA +GL+ K V I+G + + + G T Sbjct: 216 D-IDLIIC-NDSTALPGQAQAAQNKGLTAKNVTITGFASPNSMKQYCNDGILTRWGLWDC 273 Query: 268 TLLANTAAEIAVELGNGQEPK 288 + +A + +G K Sbjct: 274 GIQGAMGCYMAYYIASGNSVK 294 >3O75-A nrPDB Length = 272 Score = 63.7 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 40/226 (17%), Positives = 84/226 (37%), Gaps = 14/226 (6%) Query: 25 EVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDV 84 +G + DL + + + A + G ++ + S++ +++ + R D Sbjct: 2 TRTLGFILPDLENPSYARIAKQLEQGARARGYQLLIASSDDQPDSERQLQQLFRARRCDA 61 Query: 85 LVII---PYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALV 141 L + P +E + +G+ V+A DR ++ A IS D + +L A L Sbjct: 62 LFVASCLPPEDDSY----RELQDKGLPVIAIDRRLDPAHFCSVISDDRDASRQLAASLLS 117 Query: 142 DIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIM 201 + L+G P + ++ G + L+ Y V + + E ++M Sbjct: 118 SAPR--SIALIGARPELSVSQARAGGFDEALQGYTGE-----VRRYQGEAFSRECGQRLM 170 Query: 202 ENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDAD 247 + + DA+V ++ G L A+ + + G D Sbjct: 171 QQLIDDLGGLPDALVTTSYVLLQGVFDTLQARPVDSRQLQLGTFGD 216 >5YSZ-A nrPDB Length = 360 Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 33/216 (15%), Positives = 80/216 (37%), Gaps = 13/216 (6%) Query: 77 MINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADI-DFYISFDNEKVGEL 135 + + VD ++++ + + + + G+ + R + + Y+ DN G Sbjct: 140 LAGQHVDGVLLLSLHRD--DPLPQMLDEAGVPYVYGGRPLGVPEEQVSYVDIDNIGGGRQ 197 Query: 136 QAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPE 195 + L++ + + G + + + + +L ++ + + + + Sbjct: 198 ATQRLIETGHRRIATIAGPQDMVAGVERLQGYREALLAAGMEYD--ETLVSY--GDFTYD 253 Query: 196 NALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGL--SGKVAISGQDADLAGIKR 253 + + M L + +DAV A++D A++ L A G VA+ G D Sbjct: 254 SGVAAMRELLDRAPD-VDAVFAASDLMGLAALRVLRASGRRVPEDVAVVGYD---DSTVA 309 Query: 254 IAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKA 289 A +V +P L+ A + V+ G+ + Sbjct: 310 EHAEPPMTSVNQPTELMGREMARLLVDRITGETTEP 345 >3H5O-A nrPDB Length = 339 Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 45/277 (16%), Positives = 97/277 (35%), Gaps = 18/277 (6%) Query: 18 NVAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENM 77 + A AK + + I L + + ++ G ++ + +++ + ++ + Sbjct: 55 STLASAKSRTVLVLIPSLANTVFLETLTGIETVLDAAGYQMLIGNSHYDAGQELQLLRAY 114 Query: 78 INRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQA 137 + D ++I + + Q + V+ + +D + F E G Sbjct: 115 LQHRPDGVLITGLSH--AEPFERILSQHALPVVYMMDLADDG--RCCVGFSQEDAGAAIT 170 Query: 138 KALVDIVPQGNYFLMGGSPVDNNAKLFRAG-QMKVLKPYVDSGKIKVVGDQWVDGWLPEN 196 + L+ + FL G+ +D G + + ++ + Q + + Sbjct: 171 RHLLSRGKRRIGFL--GAQLDERVMKRLDGYRAALDAADCRDAGLEWLDPQPSSMQMGAD 228 Query: 197 ALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGL--SGKVAISGQ-DADLAGIKR 253 L A DA+ ND A GA+ G+ ++AI+G D A Sbjct: 229 MLDRA----LAERPDCDALFCCNDDLAIGALARSQQLGIAVPERLAIAGFNDLQPAAW-- 282 Query: 254 IAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKAD 290 TV P + AA+ ++L +G+EP + Sbjct: 283 --CTPPLTTVATPRRDIGVHAAKALLQLIDGEEPASR 317 >3BIL-A nrPDB Length = 348 Score = 62.1 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 50/275 (18%), Positives = 94/275 (34%), Gaps = 20/275 (7%) Query: 22 HAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRG 81 ++ IG+ + L + A G + ++N + T +E + + G Sbjct: 63 SSRSNTIGVIVPSLINHYFAAMVTEIQSTASKAGLATIITNSNEDATTMSGSLEFLTSHG 122 Query: 82 VDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALV 141 VD ++ +P N +++ +++G+ V+ DR + D + N + G A L+ Sbjct: 123 VDGIICVPNEECA--NQLEDLQKQGMPVVLVDREL-PGDSTIPTATSNPQPGIAAAVELL 179 Query: 142 DIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQ--WVDGWLPENALK 199 N L G +++ K + KI G+Q ++ G+ + Sbjct: 180 AH----NNALPIGYLSGPMDTSTGRERLEDFKAACANSKI---GEQLVFLGGYEQSVGFE 232 Query: 200 IMENALTANNNKIDAVVASNDATAGGAIQALSAQGLS--GKVAISGQDADLAGIKRIAAG 257 L + A + G I+A GL V++ G D Sbjct: 233 GATKLLDQGA---KTLFAGDSMMTIGVIEACHKAGLVIGKDVSVIGFDTHPL---FALQP 286 Query: 258 TQTMTVYKPITLLANTAAEIAVELGNGQEPKADTT 292 + + + LA A I EL G P T Sbjct: 287 HPLTVIDQNVEQLAQRAVSILTELIAGTVPSVTKT 321 >8ABP-A nrPDB Length = 306 Score = 60.2 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 56/318 (17%), Positives = 115/318 (36%), Gaps = 34/318 (10%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 + +K+G + +Q + K + LG +V ++ A + E ++ I+++ G Sbjct: 1 ENLKLGFLVKQPEEPWFQTEWKFADKAGKDLGFEV-IKIAVPDGEKTLNAIDSLAASGAK 59 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDA-----DIDFYISFDNEKVGELQAK 138 VI + ++ S +V +A+ +KV+A D +A D + K+GE Q + Sbjct: 60 GFVICTPDPKLGSAIVAKARGYDMKVIAVDDQFVNAKGKPMDTVPLVMLAATKIGERQGQ 119 Query: 139 ALVDIVPQGNYFLMGGSPVDNNAKLFRAG--QMKVLKPYVDSGKI--KVVGDQWVDGWLP 194 L + + + + + + A + + + K + Sbjct: 120 ELYKEMQKRGWDVKESAVMAITANELDTARRRTTGSMDALKAAGFPEKQIYQVPTKSNDI 179 Query: 195 ENALKIMENALTANNN-KIDAVVASNDATAGGAIQALSAQGLSGKVA----ISGQDADLA 249 A + L + K +V ND+T G ++A QG I+G DA Sbjct: 180 PGAFDAANSMLVQHPEVKHWLIVGMNDSTVLGGVRATEGQGFKAADIIGIGINGVDAVSE 239 Query: 250 GIKRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVP----SRLL 305 K A G ++ + ++E+ N KDV + + Sbjct: 240 LSKAQATG-FYGSLLPSPDVHGYKSSEM--------------LYNWVAKDVEPPKFTEVT 284 Query: 306 TPIDVNKNNIKDTVIKDG 323 + + ++N K+ + K G Sbjct: 285 DVVLITRDNFKEELEKKG 302 >3GYB-A nrPDB Length = 280 Score = 60.2 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 40/269 (14%), Positives = 89/269 (33%), Gaps = 20/269 (7%) Query: 24 KEVKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVD 83 + I + IDD + G ++ V + ++ I + ++ D Sbjct: 4 RTQLIAVLIDDYSNPWFIDLIQSLSDVLTPKGYRLSVIDSLTSQAG-TDPITSALSMRPD 62 Query: 84 VLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDI 143 ++I + I A ++ D+ + E+ K L+D+ Sbjct: 63 GIIIAQDIPDFTVP------DSLPPFVIAGTRITQASTHDSVANDDFRGAEIATKHLIDL 116 Query: 144 VPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMEN 203 L GS + + + + ++ + + ++ + Sbjct: 117 GHTHIAHLRVGSGAGLRRF-------ESFEATMRAHGLEPLSNDYLGPAVEHAGYTETLA 169 Query: 204 ALTANNNKIDAVVASNDATAGGAIQALSAQGL--SGKVAISGQDADLAGIKRIAAGTQTM 261 L + ++ A+ +SND TA GA+ A GL ++I G D R+ T Sbjct: 170 LLKEHP-EVTAIFSSNDITAIGALGAARELGLRVPEDLSIIGYDNTPLAQTRLINLT--- 225 Query: 262 TVYKPITLLANTAAEIAVELGNGQEPKAD 290 T+ + AA + + + + + P + Sbjct: 226 TIDDNSIGVGYNAALLLLSMLDPEAPHPE 254 >4KZK-A nrPDB Length = 337 Score = 57.5 bits (137), Expect = 9e-09, Method: Composition-based stats. Identities = 44/250 (17%), Positives = 84/250 (33%), Gaps = 16/250 (6%) Query: 26 VKIGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVL 85 VKIG + W +D F ++A V+ A + E + ++++ + + Sbjct: 37 VKIGFVVKQPDDP-WFQDEWRFAEQAAKDKHFTLVKIAAPSGEKVSTALDSLAAQKAQGV 95 Query: 86 VIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDA-----DIDFYISFDNEKVGELQAKAL 140 +I + ++ + +AK+ G+K+++ D + D ++ ++G A+ Sbjct: 96 IICAPDVKLGPGIAAKAKRYGMKLMSVDDQLVDGRGAPLADVPHMGISAYRIGRQVGDAI 155 Query: 141 VDIVPQGNY------FLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLP 194 + + L A+ G V V D Sbjct: 156 AAEAKRRGWNPAEVGVLRLAYDQLPTARERTTGA--VDALKAAGFAAANVVDAPEMTADT 213 Query: 195 ENALKIMENALTANNNKIDAV-VASNDATAGGAIQALSAQGLSGKVAI-SGQDADLAGIK 252 E A A T + N V SND T GA++A +G+ I G + + Sbjct: 214 EGAFNAANIAFTKHRNFRHWVAFGSNDDTTVGAVRAGEGRGIGTDDMIAVGINGSQVALN 273 Query: 253 RIAAGTQTMT 262 A T Sbjct: 274 EFAKPKPTGF 283 >3ROT-A nrPDB Length = 297 Score = 54.8 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 25/166 (15%), Positives = 51/166 (30%), Gaps = 6/166 (3%) Query: 38 ERWQKDRDIFVKKAESLGAKVFVQ--SANGNEETQMSQIENMINRGVDVLVIIPYNGQVL 95 W K AE L + + + Q+ IE+ + + + Sbjct: 16 PYWTSLFQGAKKAAEELKVDLQILAPPGANDVPKQVQFIESALATYPSGIATTIPSDTAF 75 Query: 96 SNVVKEAKQEGIKVLAYDRMINDADID---FYISFDNEKVGELQAKALVDIVPQGNYFL- 151 S ++ A + I V+A D D + ++ DN G+ + +++ P L Sbjct: 76 SKSLQRANKLNIPVIAVDTRPKDKTKNPYLVFLGSDNLLAGKKLGEKALELTPSAKRALV 135 Query: 152 MGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENA 197 + P + G +L+ + VG + Sbjct: 136 LNPQPGHIGLEKRAYGIKTILQDKGIFFEELDVGTDPNQVQSRVKS 181 >3JVD-A nrPDB Length = 333 Score = 49.0 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 46/266 (17%), Positives = 92/266 (34%), Gaps = 28/266 (10%) Query: 28 IGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVI 87 +G+ + DL E + + + ++ G ++ V A + + Q +E++I+ ++ Sbjct: 67 VGVIVPDLSNEYYSESLQTIQQDLKAAGYQMLVAEA-NSVQAQDVVMESLISIQAAGIIH 125 Query: 88 IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQG 147 +P G ++ EGI ++ R + D+E ++++ Sbjct: 126 VPVVG-SIAP-------EGIPMVQLTRGELGPGFP-RVLCDDEAGFFQLTESVLGGSGMN 176 Query: 148 NYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTA 207 L+G + + R S + G + + + E A Sbjct: 177 IAALVGEESLSTTQERMRG----------ISHAASIYGAEVTFHFGHYSVESGEEMAQVV 226 Query: 208 NNNKI--DAVVASNDATAGGAIQALS--AQGLSGKVAISGQDADLAGIKRIAAGTQTMTV 263 NN + +VAS A G ++A + + V I G D D + AG T Sbjct: 227 FNNGLPDALIVASPRLMA-GVMRAFTRLNVRVPHDVVIGGYD-DPEWYSFVGAG--ITTF 282 Query: 264 YKPITLLANTAAEIAVELGNGQEPKA 289 P + A + V+L E Sbjct: 283 VPPHEEMGKEAVRLLVDLIENPELPT 308 >4YP9-A nrPDB Length = 345 Score = 48.3 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 45/296 (15%), Positives = 100/296 (33%), Gaps = 27/296 (9%) Query: 26 VKIGMAIDDLRL-ERWQKDRDIFVKKAESLGAKVFVQS----ANGNEETQMSQIENMINR 80 +KI + ++ + W ++ F K+ L + N + + Q + + Sbjct: 47 IKISVVYPGQQVSDYWVRNIASFEKRLYKLNINYQLNQVFTRPNADIKQQSLSLMEALKS 106 Query: 81 GVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYD-----RMINDADIDFYISFDNEKVGEL 135 D L+ + V K++ + R + Y+ FD+ + Sbjct: 107 KSDYLIFTLDTTRHRKFVEHVLDSTNTKLILQNITTPVREWDKHQPFLYVGFDHAEGSRE 166 Query: 136 QAKALVDIVPQGNYFLM----GGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDG 191 A P+ Y+ + G D F + ++ + Sbjct: 167 LATEFGKFFPKHTYYSVLYFSEGYISDVRGDTFIHQVNR-------DNNFELQSAYYTKA 219 Query: 192 WLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGI 251 ++ + +L + + +D + A + A GA+ AL+ G + I+G A + Sbjct: 220 -TKQSGYDAAKASLAKHPD-VDFIYACSTDVALGAVDALAELGRE-DIMINGWGGGSAEL 276 Query: 252 KRIAAGTQTMTVYKPITLLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTP 307 I G +TV + +T +A + E K T+ +G ++ ++ +P Sbjct: 277 DAIQKGDLDITVM---RMNDDTGIAMAEAIKWDLEDKPVPTVYSGDFEIVTKADSP 329 >5UFH-A nrPDB Length = 347 Score = 40.9 bits (94), Expect = 7e-04, Method: Composition-based stats. Identities = 41/268 (15%), Positives = 84/268 (31%), Gaps = 17/268 (6%) Query: 28 IGMAIDDLRLERWQKDRDIFVKKAESLGAKVFVQSANGNEETQMSQIENMINRGVDVLVI 87 +G+AI D D + A V + + NE + N D ++ Sbjct: 68 LGLAIFDFSQPFASYLADQIIVCAREHHYGVIINTYGQNEHGLARAMRQANNLAADGWIV 127 Query: 88 IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDNEKVGELQAKALVDIVPQ- 146 + + ++ + ++ N + L+D + Sbjct: 128 F---ADHAMGQHSKMLDQSYPLV-LTGDWDAYGKVDQVTMPNVEAMRYTTNRLLDSGYRS 183 Query: 147 ----GNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQ-WVDGWLPENALKIM 201 G +G + + +++ + I+ D + G L ++ Sbjct: 184 IALFGADGSLGARHYRQATEGTQELRVQGYMQAYEEHGIEARMDMLFSGGLLTSDSGVRA 243 Query: 202 ENALTANNNKIDAVVASNDATAGGAIQALSAQGL--SGKVAISGQDADLAGIKRIAAGTQ 259 N + + DA++ NDA A GA+ L +G+ V + G D Sbjct: 244 TNLMMDQGVRPDAIICLNDAMALGALHQLQVRGIRVPDDVQVVGFDNVPEATYA----NP 299 Query: 260 TMTVYKP-ITLLANTAAEIAVELGNGQE 286 ++T P I A A ++ +E G + Sbjct: 300 SLTTIDPHIDSYARHAVDMLIERIQGYD 327 >4CBI-A nrPDB Length = 516 Score = 34.8 bits (78), Expect = 0.049, Method: Composition-based stats. Identities = 28/159 (17%), Positives = 57/159 (35%), Gaps = 23/159 (14%) Query: 149 YFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTAN 208 M +P + ++ + K + +G +++D + ++ M+N + Sbjct: 171 VVAMTATPAGTVTTTGQKHPIEEFI-APEVMKGEDLGSEYLDIAGLKIPVEEMKNNML-- 227 Query: 209 NNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPIT 268 V A A + L A+G + SG+D + ++ + + + + V Sbjct: 228 ------VFVPTRNMAVEAAKKLKAKGYNSGYYYSGED--PSNLRVVTSQSPYVVVATN-- 277 Query: 269 LLANTAAEIAVELGNGQEPKADTTLNNGLKDVPSRLLTP 307 A E V L P D ++ GLK L+P Sbjct: 278 -----AIESGVTL-----PDLDVVVDTGLKCEKRIRLSP 306 >4WHB-E nrPDB Length = 461 Score = 34.4 bits (77), Expect = 0.080, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 37/97 (38%), Gaps = 26/97 (26%) Query: 74 IENMINRGVDVLVIIPYNGQV---------------------LSNVVKEAKQEGIKVLAY 112 + + ++RGVD+L I + V L +V+EA+ G+ VL + Sbjct: 194 VRDYLSRGVDMLKIAVSDHIVFTLVDRSVGFDRSYQTFSRPVLEVMVEEARAAGVPVLTH 253 Query: 113 DRMINDADIDFYISFD-----NEKVGELQAKALVDIV 144 + D + D N +G+ L+D + Sbjct: 254 SVSVEALDTSVELGADVLIHANYTLGQEIPNYLIDKI 290 >5WSO-A nrPDB Length = 476 Score = 32.9 bits (73), Expect = 0.20, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 53/150 (35%), Gaps = 23/150 (15%) Query: 149 YFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTAN 208 M +P + + ++ + K + +G Q++D + + M+ + Sbjct: 139 VVAMTATPAGSVTTTGQKHPIEEFI-APEVMKGEDLGSQFLDIAGLKIPVDEMKGNML-- 195 Query: 209 NNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPIT 268 V A + L A+G + SG+D A ++ + + + + V Sbjct: 196 ------VFVPTRNMAVEVAKKLKAKGYNSGYYYSGED--PANLRVVTSQSPYVIVATN-- 245 Query: 269 LLANTAAEIAVELGNGQEPKADTTLNNGLK 298 A E V L P DT ++ GLK Sbjct: 246 -----AIESGVTL-----PDLDTVIDTGLK 265 >5ZEB-b nrPDB Length = 277 Score = 32.5 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 40/114 (35%), Gaps = 10/114 (8%) Query: 58 VFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLA-YDRMI 116 + + E + I +M + V + + V EA++ GI V+A D Sbjct: 135 LMLTREKNKLERSLGGIRDM--QKVPS-AVWVVDTNKEHIAVGEARKLGIPVIAILDTNC 191 Query: 117 NDADIDFYI--SFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQ 168 + +D+ I + D + L K + V +G + + + G Sbjct: 192 DPDVVDYPIPGNDDAIRSAALLTKVIASAVAEG----LQARAGQGSGEKPAEGA 241 >1BVU-A nrPDB Length = 418 Score = 31.7 bits (70), Expect = 0.43, Method: Composition-based stats. Identities = 39/191 (20%), Positives = 69/191 (36%), Gaps = 31/191 (16%) Query: 161 AKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPEN------ALKIMENALTANNNKIDA 214 A+ + V+ PY D V + + W+ + +T + Sbjct: 123 ARGYVRAIYDVISPYTDIPAPDVYTNPQIMAWMMDEYETISRRKDPSFGVITGKPPSVGG 182 Query: 215 VVASNDATAGGAIQALSAQGLS------GK-VAISGQ----------DADLAGIKRIAAG 257 +VA DATA GA + + GK +AI G ++ G+K +A Sbjct: 183 IVARMDATARGASYTVREAAKALGMDLKGKTIAIQGYGNAGYYMAKIMSEEYGMKVVAVS 242 Query: 258 TQTMTVYKPITLLANTAAEIAVELGNGQE-PKADTTLNNGLKDVPSRLLTPIDV------ 310 +Y P L A+ + G+ ++ P A N L ++ +L P + Sbjct: 243 DTKGGIYNPDGLNADEVLAWKKKTGSVKDFPGATNITNEELLELEVDVLAPSAIEEVITK 302 Query: 311 -NKNNIKDTVI 320 N +NIK ++ Sbjct: 303 KNADNIKAKIV 313 >5WX1-A nrPDB Length = 733 Score = 30.9 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 52/147 (35%), Gaps = 11/147 (7%) Query: 149 YFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTAN 208 M +P + ++ + K + +G +++D LKI + +N Sbjct: 396 VVAMTATPAGTVTTTGQKHPIEEFI-APEVMKGEDLGSEYLD----IAGLKIPVEEMKSN 450 Query: 209 NNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADLAGIKRIAAGTQTMTVYKPIT 268 V A + L A+G + SG+D + ++ + + + + V Sbjct: 451 ----MLVFVPTRNMAVETAKKLKAKGYNSGYYYSGED--PSNLRVVTSQSPYVVVATNAI 504 Query: 269 LLANTAAEIAVELGNGQEPKADTTLNN 295 T ++ V + G + + L++ Sbjct: 505 ESGVTLPDLDVVVDTGLKCEKRIRLSS 531 >2HIX-A nrPDB Length = 621 Score = 30.5 bits (67), Expect = 0.94, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 69/198 (34%), Gaps = 34/198 (17%) Query: 84 VLVIIPYNGQVLSNV---VKEAKQEGIKVLAYD---RMINDADIDFYISFDNEKVGELQA 137 + I P + LSN +K+ I YD I+ + +I + Q Sbjct: 250 GIPIRPMLAERLSNPEEILKKMGGNAIVDYKYDGERAQIHKKEDKIFIFSRRLENITSQY 309 Query: 138 KALVDIVPQ---GNYFLMGGSPVDNNAKLFRAGQMKVLKPYV----DSGKIKVVGDQWVD 190 +VD V + G F++ G V + + +G+M+ + + S + + + V+ Sbjct: 310 PDVVDYVSKYIEGKEFIIEGEIVAIDPE---SGEMRPFQELMHRKRKSDIYEAIKEYPVN 366 Query: 191 GWLPE----NALKIMENALTANNNKIDAVVASNDATAGG--------------AIQALSA 232 +L + + L A ++++V ND +A+S Sbjct: 367 VFLFDLMYYEDVDYTTKPLEARRKLLESIVKPNDYVKIAHHIQANNVEDLKSFFYRAISE 426 Query: 233 QGLSGKVAISGQDADLAG 250 G V G+DA Sbjct: 427 GGEGVMVKAIGKDAIYQA 444 >6DZI-8 nrPDB Length = 228 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 19/93 (20%), Positives = 36/93 (38%), Gaps = 6/93 (6%) Query: 58 VFVQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLA-YDRMI 116 + + E + I +M + V + + V EA++ GI V+A D Sbjct: 135 LMLTREKNKLERSLGGIRDM--QKVPS-AVWVVDTNKEHIAVGEARKLGIPVIAILDTNC 191 Query: 117 NDADIDFYI--SFDNEKVGELQAKALVDIVPQG 147 + +D+ I + D + L K + V +G Sbjct: 192 DPDVVDYPIPGNDDAIRSAALLTKVIASAVAEG 224 >3S99-A nrPDB Length = 356 Score = 30.5 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 17/96 (17%), Positives = 39/96 (40%), Gaps = 8/96 (8%) Query: 19 VAAHAKEVKIGMAIDDLRLERWQKDRDIFVKKAESLG----AKVFVQSANGNEETQMSQI 74 +AA + I I + + + + F+ A+S+ KV ++ + + Sbjct: 142 IAAKMSKKGIAGYIGSVPVPEVVQGINSFMLGAQSVNPDFRVKVIWVNSWFDPGKEADAA 201 Query: 75 ENMINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVL 110 + +I++GVD ++ + ++ A GIK Sbjct: 202 KALIDQGVD-IITQHTDSTA---AIQVAHDRGIKAF 233 >5V7X-A nrPDB Length = 752 Score = 30.2 bits (66), Expect = 1.2, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 28/68 (41%), Gaps = 3/68 (4%) Query: 158 DNNAKLFRAG--QMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAV 215 D + +++AG +K L P + K+ + + +M+N T N N I + Sbjct: 537 DLSQAMWKAGHALIKSLFPEGNPAKVNLKRPPTAGSQFKASVATLMKNLQTKNPNYIRCI 596 Query: 216 VASNDATA 223 ND A Sbjct: 597 -KPNDKKA 603 >6FXC-Ab nrPDB Length = 226 Score = 29.8 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 28/62 (45%), Gaps = 3/62 (4%) Query: 90 YNGQVLSNVVKEAKQEGIKVL-AYDRMINDADIDFYI--SFDNEKVGELQAKALVDIVPQ 146 + + N + EA++ I ++ D + +ID+ I + D + +L + D + + Sbjct: 164 VDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADAILE 223 Query: 147 GN 148 G Sbjct: 224 GQ 225 >1A6D-B nrPDB Length = 543 Score = 29.8 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 33/185 (17%), Positives = 62/185 (33%), Gaps = 19/185 (10%) Query: 63 ANGNEETQMSQIENMINRGVDVLVI--IPYNGQVLSNVVKEAKQEGIKVLAYDRMINDAD 120 A+ + + +I I L++ + S V + K I A + D Sbjct: 129 ASEEAKRVIDEISTKIGADEKALLLKMAQTSLNSKSASVAKDKLAEISYEAVKSVAELRD 188 Query: 121 IDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGK 180 +Y+ FDN +V + Q A+ D L+ G VD + + V K Sbjct: 189 GKYYVDFDNIQVVKKQGGAIDDTQ------LINGIIVD------KEKVHPGMPDVVKDAK 236 Query: 181 IKVVGDQWVDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVA 240 I ++ D L + N + + I +A + + + + G + + Sbjct: 237 IALL-----DAPLEIKKPEFDTNLRIEDPSMIQKFLAQEENMLREMVDKIKSVGANVVIT 291 Query: 241 ISGQD 245 G D Sbjct: 292 QKGID 296 >1X18-E nrPDB Length = 231 Score = 29.4 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 25/53 (47%), Gaps = 2/53 (3%) Query: 77 MINRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYISFDN 129 ++ R D + + + + V+EA++ I V+A +D D+ YI N Sbjct: 145 LLKRLPDAIFV--VDPTKEAIAVREARKLFIPVIALADTDSDPDLVDYIIPGN 195 >5LK8-C nrPDB Length = 430 Score = 29.4 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 12/81 (14%), Positives = 26/81 (32%), Gaps = 3/81 (3%) Query: 141 VDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKI 200 +D + +F+ G ++R G + PY + + + A+ Sbjct: 331 LDKINGTEWFIPEGEYTLGYGVVWRDGAYAYMVPYPLTPLGEKIAQYTASLLASNTAISQ 390 Query: 201 MENALTANNNKIDAVVASNDA 221 + + + I AS D Sbjct: 391 IRPYI---PDYIVDSAASKDN 408 >5ND9-b nrPDB Length = 255 Score = 29.0 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 12/62 (19%), Positives = 28/62 (45%), Gaps = 3/62 (4%) Query: 90 YNGQVLSNVVKEAKQEGIKVL-AYDRMINDADIDFYI--SFDNEKVGELQAKALVDIVPQ 146 + + N + EA++ I ++ D + +ID+ I + D + +L + D + + Sbjct: 164 VDPRKERNAIAEARKLNIPIVGIVDTNCDPDEIDYVIPANDDAIRAVKLLTAKMADAILE 223 Query: 147 GN 148 G Sbjct: 224 GQ 225 >3QM3-A nrPDB Length = 357 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 14/117 (11%), Positives = 38/117 (32%), Gaps = 8/117 (6%) Query: 79 NRGVDVLVIIPYNGQVLSNVVKEAKQEGIKVLAYDRMINDADIDFYIS---FDNEKVGEL 135 G + + ++ V++ AK+ V+ ++ FY + E +G + Sbjct: 29 AEGFAIPAVNVVGTDSINAVLEAAKKVNSPVII---QFSNGGAKFYAGKNCPNGEVLGAI 85 Query: 136 QAKALVDIVPQ--GNYFLMGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVD 190 V ++ + G ++ + G ++ Y + + +D Sbjct: 86 SGAKHVHLLAKAYGVPVILHTDHAARKLLPWIDGLIEANAQYKKTHGQALFSSHMLD 142 >5MYJ-AB nrPDB Length = 255 Score = 28.2 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 3/61 (4%) Query: 90 YNGQVLSNVVKEAKQEGIKVLA-YDRMINDADIDFYI--SFDNEKVGELQAKALVDIVPQ 146 + VKEAK GI V+A D + ID I + D + +L + D + + Sbjct: 164 VDPHAEQIAVKEAKTLGIPVVAMVDTNADPEPIDVVIPANDDAIRAVKLITAKMADAIIE 223 Query: 147 G 147 G Sbjct: 224 G 224 Score = 28.2 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 34/204 (16%), Positives = 74/204 (36%), Gaps = 27/204 (13%) Query: 103 KQEGIKVLAYDRMINDADIDFYISFDNEKVGE---------LQAKALVDIV-PQGNYFL- 151 ++ GI V+ + + D + + + G A+A+ + G Y++ Sbjct: 34 ERNGIHVIDLQKTVKLVDDAYNYVKNASQEGAVVLFVGTKKQAAEAVKEEALRAGQYYVN 93 Query: 152 ---MGGSPVDNNAKLFRAGQMKVLKPYVDSGKIKVVGDQWVDGWLPENALKIMENAL--T 206 +GG + N R ++K + + G +V+ + + L + +E + Sbjct: 94 HRWLGGMLTNWNTIQTRVTRLKEINKMEEEGTFEVLPKK--EVVLLNKERERLEKFIGGI 151 Query: 207 ANNNKIDAVVASNDATAGGAIQALSAQGLSG--KVAISGQDADLAGIKRIAAGTQTMTVY 264 A+ +I V+ D A A+ G VA+ +AD I + Sbjct: 152 ADMPRIPDVMYIVDPHAEQI--AVKEAKTLGIPVVAMVDTNADPEPIDVVIPANDDA--- 206 Query: 265 KPITLLANTAAEIAVELGNGQEPK 288 I + A++A + G++ + Sbjct: 207 --IRAVKLITAKMADAIIEGRQGE 228 >3QY6-A nrPDB Length = 262 Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 8/70 (11%), Positives = 26/70 (37%), Gaps = 10/70 (14%) Query: 60 VQSANGNEETQMSQIENMINRGVDVLVIIPYNGQVL----SNVVKEAKQEGIKVLAYDRM 115 + G+ + + +G+ ++ P++ + V+EA + ++ Sbjct: 12 MDDGAGDSADSIEMARAAVRQGIRTIIATPHHNNGVYKNEPAAVREAADQ------LNKR 65 Query: 116 INDADIDFYI 125 + DI ++ Sbjct: 66 LIKEDIPLHV 75 >1SO4-A nrPDB Length = 216 Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 40/128 (31%), Gaps = 7/128 (5%) Query: 189 VDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGLSGKVAISGQDADL 248 D + + + AN + + + ++ TA GA+ ++ ++G Sbjct: 61 ADAAIADAGKILSRMCFEANADWVTVICCADINTAKGALDVAKEFNGDVQIELTGYWTWE 120 Query: 249 AGIKRIAAGTQTMTVYKPITLLANTAAE------IAVELGNGQEPKADTTLNNGLKDVPS 302 + AG VY A++ + K T L+D+P Sbjct: 121 QAQQWRDAG-IGQVVYHRSRDAQAAGVAWGEADITAIKRLSDMGFKVTVTGGLALEDLPL 179 Query: 303 RLLTPIDV 310 PI V Sbjct: 180 FKGIPIHV 187 >6QGB-A nrPDB Length = 596 Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 14/99 (14%), Positives = 32/99 (32%), Gaps = 3/99 (3%) Query: 117 NDADIDFYISFDNEKVGELQAKALVDIVPQGNYFLMGGSPVDNNAKLFRAGQMKVLKPYV 176 AD ++I G + L P ++ G+P K +G Sbjct: 207 RAADKSYFIGC---SEGGREGMMLSQRFPSHYDGIVAGAPGYQLPKAGISGAWTTQSLAP 263 Query: 177 DSGKIKVVGDQWVDGWLPENALKIMENALTANNNKIDAV 215 + + G ++ + L ++ A+ + +D + Sbjct: 264 AAVGLDAQGVPLINKSFSDADLHLLSQAILGTCDALDGL 302 >1Z15-A nrPDB Length = 344 Score = 27.8 bits (60), Expect = 6.8, Method: Composition-based stats. Identities = 19/138 (13%), Positives = 45/138 (32%), Gaps = 8/138 (5%) Query: 121 IDFYISFDNEKVGELQAKALVDIVPQGNYFL--MGGSPVDNNAKLFRAGQMKVLKPYVDS 178 + + + D ++ + K + D + Y + + S + ++ + ++ P + Sbjct: 47 VKYDDACDPKQAVAVANKVVNDGIK---YVIGHLCSSSTQPASDIYEDEGILMITPAATA 103 Query: 179 GKIKVVGDQW---VDGWLPENALKIMENALTANNNKIDAVVASNDATAGGAIQALSAQGL 235 ++ G Q G + + L + A+V G +A+ Sbjct: 104 PELTARGYQLILRTTGLDSDQGPTAAKYILEKVKPQRIAIVHDKQQYGEGLARAVQDGLK 163 Query: 236 SGKVAISGQDADLAGIKR 253 G + D AG K Sbjct: 164 KGNANVVFFDGITAGEKD 181 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.123 0.280 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,465,043 Number of Sequences: 36641 Number of extensions: 335374 Number of successful extensions: 1248 Number of sequences better than 10.0: 71 Number of HSP's better than 10.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 51 Number of HSP's that attempted gapping in prelim test: 1081 Number of HSP's gapped (non-prelim): 134 length of query: 330 length of database: 10,336,785 effective HSP length: 97 effective length of query: 233 effective length of database: 6,782,608 effective search space: 1580347664 effective search space used: 1580347664 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 59 (27.5 bits)