BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P37382 (297 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3H0G-C nrPDB 616 e-177 3HOY-C nrPDB 320 5e-88 3J0K-C nrPDB 317 3e-87 5X4Z-C nrPDB 301 2e-82 5IYA-C nrPDB 221 2e-58 5LMX-C nrPDB 99 2e-21 6F44-C nrPDB 99 3e-21 4QIW-D nrPDB 82 3e-16 2WB1-D nrPDB 72 2e-13 2PMZ-D nrPDB 71 6e-13 1IW7-A nrPDB 35 0.030 1HQM-A nrPDB 33 0.16 3JWJ-A nrPDB 29 2.2 5LJ3-O nrPDB 28 3.4 6B44-C nrPDB 28 4.2 5GMK-c nrPDB 27 7.3 2F6U-A nrPDB 27 7.5 5WQ8-A nrPDB 27 8.2 >3H0G-C nrPDB Length = 297 Score = 616 bits (1588), Expect = e-177, Method: Compositional matrix adjust. Identities = 297/297 (100%), Positives = 297/297 (100%) Query: 1 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE 60 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE Sbjct: 1 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE 60 Query: 61 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYAR 120 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYAR Sbjct: 61 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYAR 120 Query: 121 DLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFE 180 DLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFE Sbjct: 121 DLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFE 180 Query: 181 YDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIP 240 YDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIP Sbjct: 181 YDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIP 240 Query: 241 PNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEMNWSPYQNGEENTW 297 PNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEMNWSPYQNGEENTW Sbjct: 241 PNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEMNWSPYQNGEENTW 297 >3HOY-C nrPDB Length = 347 Score = 320 bits (820), Expect = 5e-88, Method: Compositional matrix adjust. Identities = 147/276 (53%), Positives = 207/276 (75%), Gaps = 13/276 (4%) Query: 6 HITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHR 65 + IR SK++VDF+L+N LA+ANSLRRV++AEIPT+AID VE+ NT+V+ DEF+AHR Sbjct: 36 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 95 Query: 66 LGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVS 125 LG+IPL S +I++ LEY+R+C C+ +C KCSV L L A E T +Y++DLV+ Sbjct: 96 LGLIPLQSMDIEQ-----LEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 150 Query: 126 SN---SSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYD 182 SN ++GHPI+ D + G LICKLRK QE+ L C+AKKGIAKEHAKW P +A+ FEYD Sbjct: 151 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 210 Query: 183 PWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPN 242 PWNKL+HTDYW+E D+ EWP+SKN ++E+PP EG+PF+++ + FYM+VESVGSIP + Sbjct: 211 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 270 Query: 243 EIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNM 278 +++V+G+ LQ+K+A ++ L TQ+ +++N Sbjct: 271 QVVVRGIDTLQKKVASILLAL-----TQMDQDKVNF 301 >3J0K-C nrPDB Length = 268 Score = 317 bits (813), Expect = 3e-87, Method: Compositional matrix adjust. Identities = 144/263 (54%), Positives = 201/263 (76%), Gaps = 8/263 (3%) Query: 6 HITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHR 65 + IR SK++VDF+L+N LA+ANSLRRV++AEIPT+AID VE+ NT+V+ DEF+AHR Sbjct: 7 QVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAHR 66 Query: 66 LGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVS 125 LG+IPL S +I++ LEY+R+C C+ +C KCSV L L A E T +Y++DLV+ Sbjct: 67 LGLIPLQSMDIEQ-----LEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVIV 121 Query: 126 SN---SSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYD 182 SN ++GHPI+ D + G LICKLRK QE+ L C+AKKGIAKEHAKW P +A+ FEYD Sbjct: 122 SNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEYD 181 Query: 183 PWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPN 242 PWNKL+HTDYW+E D+ EWP+SKN ++E+PP EG+PF+++ + FYM+VESVGSIP + Sbjct: 182 PWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPVD 241 Query: 243 EIMVQGLRILQEKLAVLVRDLDE 265 +++V+G+ LQ+K+A ++ L + Sbjct: 242 QVVVRGIDTLQKKVASILLALTQ 264 >5X4Z-C nrPDB Length = 304 Score = 301 bits (771), Expect = 2e-82, Method: Compositional matrix adjust. Identities = 142/277 (51%), Positives = 203/277 (73%), Gaps = 9/277 (3%) Query: 1 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE 60 M E + I N + V+ +L++ +L++ANSLRR +LAE+PT+AIDLVEI +NTSV+ DE Sbjct: 1 MSKEPKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLADE 60 Query: 61 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGE-GTMEIYA 119 F++HRLG+IPL S +++E ++Y+R+C C+ YC +CSV L L+A+ GE GT ++Y+ Sbjct: 61 FISHRLGLIPLVSEDVEE-----MKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYS 115 Query: 120 RDLVVSS---NSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSA 176 L+ S N ++G P+ D +G L+CKLR QE+++RCIAKKGIAKEHAKWSP SA Sbjct: 116 SSLIKVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSA 175 Query: 177 VAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESV 236 +AFEYDP NKL+HTD+WFE DA EWP SK A WEEPP+ GE F+++ +P RFYM VE+ Sbjct: 176 IAFEYDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETT 235 Query: 237 GSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSA 273 GS+ N++ +G++ LQEKLA ++ +L+ +P +A Sbjct: 236 GSLKANQVFSRGIKTLQEKLANVLFELENSRPANTTA 272 >5IYA-C nrPDB Length = 275 Score = 221 bits (564), Expect = 2e-58, Method: Compositional matrix adjust. Identities = 119/269 (44%), Positives = 172/269 (63%), Gaps = 20/269 (7%) Query: 7 ITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRL 66 + I ++ +V F++ NT LAVANS+RRV +AE+P +AID V+I+ N+SV+ DEF+AHRL Sbjct: 9 VRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEFIAHRL 68 Query: 67 GMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVSS 126 G+IPL S +I + L+Y+R+C C+++CP+CSVE L+ +C + T + +RDL+ S Sbjct: 69 GLIPLISDDIVD----KLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRDLI--S 122 Query: 127 NSSLGHPILADPKSRGP---------LICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAV 177 NS P+ + + P LI KLRK QE+ LR AKKG KEHAKW+PT+ V Sbjct: 123 NSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWNPTAGV 182 Query: 178 AFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVG 237 AFEYDP N L+HT Y EWPKS+ ++ +E + P++ +P RFY +VES G Sbjct: 183 AFEYDPDNALRHTVY----PKPEEWPKSEYSELDEDESQA-PYDPNGKPERFYYNVESCG 237 Query: 238 SIPPNEIMVQGLRILQEKLAVLVRDLDEE 266 S+ P I++ L L++KL+ L L E Sbjct: 238 SLRPETIVLSALSGLKKKLSDLQTQLSHE 266 >5LMX-C nrPDB Length = 380 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 85/294 (28%), Positives = 138/294 (46%), Gaps = 48/294 (16%) Query: 7 ITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRL 66 + I ++ +F L N ++AN+ RR++++E+P+VA + V NTSV+ DE LAHR+ Sbjct: 42 VNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRI 101 Query: 67 GMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTG-----EGTME----- 116 G++PL +P + + D +++ + ++ L LN KCT +G+ + Sbjct: 102 GLVPLKV----DPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELY 157 Query: 117 ----IYARDLVV-----SSNSSLGHPIL-ADPKSRGPLICKLRKEQEISLRCIAKKGIAK 166 +YARDL S + P++ ADP L+ KLR QEISL+ GI Sbjct: 158 NNAHVYARDLKFEPQGRQSTTFADCPVVPADPDI---LLAKLRPGQEISLKAHCILGIGG 214 Query: 167 EHAKWSPTSAVAFEYDPW-NKLQ----HTDYWFEN---------DADAEWPKSKNADWEE 212 +HAK+SP S ++ P N LQ + F+ D ++ K+A + Sbjct: 215 DHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDT 274 Query: 213 PPRE-------GEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVL 259 RE + F +VES G++ P EI + +RIL+ K L Sbjct: 275 VSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNKAEYL 328 >6F44-C nrPDB Length = 335 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 85/294 (28%), Positives = 138/294 (46%), Gaps = 48/294 (16%) Query: 7 ITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRL 66 + I ++ +F L N ++AN+ RR++++E+P+VA + V NTSV+ DE LAHR+ Sbjct: 42 VNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVLAHRI 101 Query: 67 GMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTG-----EGTME----- 116 G++PL +P + + D +++ + ++ L LN KCT +G+ + Sbjct: 102 GLVPLKV----DPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDPKELY 157 Query: 117 ----IYARDLVV-----SSNSSLGHPIL-ADPKSRGPLICKLRKEQEISLRCIAKKGIAK 166 +YARDL S + P++ ADP L+ KLR QEISL+ GI Sbjct: 158 NNAHVYARDLKFEPQGRQSTTFADCPVVPADPDI---LLAKLRPGQEISLKAHCILGIGG 214 Query: 167 EHAKWSPTSAVAFEYDPW-NKLQ----HTDYWFEN---------DADAEWPKSKNADWEE 212 +HAK+SP S ++ P N LQ + F+ D ++ K+A + Sbjct: 215 DHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDARKDT 274 Query: 213 PPRE-------GEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVL 259 RE + F +VES G++ P EI + +RIL+ K L Sbjct: 275 VSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNKAEYL 328 >4QIW-D nrPDB Length = 259 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 80/275 (29%), Positives = 111/275 (40%), Gaps = 74/275 (26%) Query: 15 NSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRLGMIPLDSS 74 +S+ F+++ + AN+LRR +L+E+PT A+D VE N S + DE +AHRL MIPL + Sbjct: 12 DSIKFIVSGVDVPFANALRRTILSEVPTFAVDEVEFLENDSALFDEIIAHRLAMIPLTT- 70 Query: 75 NIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVSSNSSLGHPI 134 P + D Y S+E EG +Y+ DL SS G Sbjct: 71 ------PHERFSLDALELDDYTVTLSLE--------AEGPGMVYSGDL----KSSDGDVK 112 Query: 135 LADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYDPWNKLQHTDYWF 194 A+P I KL + Q ++ A+ G K+HAKW P F Y + H Sbjct: 113 PANPNIP---IVKLAEGQRLTFNAYARLGRGKDHAKWQP----GFVYYKYLTKIHV---- 161 Query: 195 ENDADAEWPKSKNA-DWEE----PPREGEPF-------------------NFQEE----- 225 SK+ DWEE R G P F+E Sbjct: 162 ----------SKDVPDWEELKELAERRGLPVEESDEEIVITTIKAFYLPRKFEEHMGKGI 211 Query: 226 -----PRRFYMDVESVGSIPPNEIMVQGLRILQEK 255 P F VE+ G +P EI+ L+IL K Sbjct: 212 REEIVPGSFVFTVETNGELPVEEIVSIALKILMRK 246 >2WB1-D nrPDB Length = 265 Score = 72.4 bits (176), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 56/171 (32%), Positives = 83/171 (48%), Gaps = 19/171 (11%) Query: 17 VDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRLGMIPLDSSNI 76 +D V L N++RR + +P ++ID V N S + DE LAHRL +IP S Sbjct: 13 IDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRLALIPFTSEE- 71 Query: 77 DEPPPVGLEYTR---NC-DCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVSSNSSLGH 132 L+ R C DC + C KC ++++ A+ E M +Y++D + S + S+ Sbjct: 72 ------ALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKM-LYSKD-IKSEDPSI-V 122 Query: 133 PILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYDP 183 PI D P++ L Q+ISL + G KEHAK+ P S Y P Sbjct: 123 PISGDI----PIVL-LGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYYP 168 >2PMZ-D nrPDB Length = 265 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 72/267 (26%), Positives = 117/267 (43%), Gaps = 35/267 (13%) Query: 17 VDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRLGMIPLDSSNI 76 +D V L N++RR + +P +A+D V N S + DE LAHRL +IP S Sbjct: 13 IDLVFEGYPLEFVNAIRRASMLYVPIMAVDDVYFIENNSPLYDEILAHRLALIPFMSEE- 71 Query: 77 DEPPPVGLEYTR---NC-DCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVSSNSSLGH 132 L+ R C +C + C KC ++++ A+ E M IY++D + S Sbjct: 72 ------ALDTYRWPEECIECTENCEKCYTKIYIEAEAPNEPRM-IYSKD--IKSEDPSVV 122 Query: 133 PILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYDP--------- 183 PI D P++ L Q+ISL + G KEHAK+ P S Y P Sbjct: 123 PISGDI----PIVL-LGTNQKISLEARLRLGYGKEHAKFIPVSLSVVRYYPKVEILANCE 177 Query: 184 --WNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEP---FNFQEEPRRFYMDVESVGS 238 N + ++ + + EE R +F E+ ++ +++ESVGS Sbjct: 178 KAVNVCPEGVFELKDGKLSVKNELSCTLCEECLRYCNGSIRISFVED--KYILEIESVGS 235 Query: 239 IPPNEIMVQGLRILQEKLAVLVRDLDE 265 + P I+++ + + K+ L + L E Sbjct: 236 LKPERILLEAGKSIIRKIEELEKKLVE 262 >1IW7-A nrPDB Length = 315 Score = 35.4 bits (80), Expect = 0.030, Method: Compositional matrix adjust. Identities = 50/197 (25%), Positives = 81/197 (41%), Gaps = 30/197 (15%) Query: 8 TIRNISKNSVDFVL----TNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLA 63 T+R + +FVL + + N LRR++L+ IP A+ TSV ++ L Sbjct: 12 TVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAV--------TSVYIEDVL- 62 Query: 64 HRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKC-SVELFLNAKCTGEGTMEIYARDL 122 H IP ++ E + + P +V L L A EG E+ ARD Sbjct: 63 HEFSTIPGVKEDVVEI----ILNLKELVVRFLNPSLQTVTLLLKA----EGPKEVKARDF 114 Query: 123 VVSSNSSLGHPIL--ADPKSRGPLICKLRKEQEISLRCIAKKGIAKE------HAKWSPT 174 + ++ + +P L A + G L ++R ++ + K GI A +SP Sbjct: 115 LPVADVEIMNPDLHIATLEEGGRLNMEVRVDRGVGYVPAEKHGIKDRINAIPVDAVFSPV 174 Query: 175 SAVAFEYDPWNKLQHTD 191 VAF+ + Q TD Sbjct: 175 RRVAFQVEDTRLGQRTD 191 >1HQM-A nrPDB Length = 313 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 43/175 (24%), Positives = 71/175 (40%), Gaps = 25/175 (14%) Query: 25 SLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRLGMIPLDSSNIDEPPPVGL 84 + + N LRR++L+ IP A+ TSV ++ L H IP ++ E + Sbjct: 33 GVTLGNPLRRILLSSIPGTAV--------TSVYIEDVL-HEFSTIPGVKEDVVEI----I 79 Query: 85 EYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVSSNSSLGHPIL--ADPKSRG 142 + P+ L L A EG E+ A D S++ + +P L A + G Sbjct: 80 LNLKELVVRFLDPRWRTTLILRA----EGPKEVRAVDFTPSADVEIMNPDLHIATLEEGG 135 Query: 143 PLICKLRKEQEISLRCIAKKGIAKE------HAKWSPTSAVAFEYDPWNKLQHTD 191 L ++R ++ + + GI A +SP VAF+ + Q TD Sbjct: 136 KLYMEVRVDRGVGYVPAERHGIKDRINAIPVDAIFSPVRRVAFQVEDTRLGQRTD 190 >3JWJ-A nrPDB Length = 202 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 23/50 (46%), Gaps = 6/50 (12%) Query: 177 VAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEP 226 V F P KL+H D+ FE W +S+ +W E +N Q +P Sbjct: 137 VKFANLPAGKLRHKDHRFE------WTRSQFQNWANKITERFAYNVQFQP 180 >5LJ3-O nrPDB Length = 590 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 13/49 (26%), Positives = 27/49 (55%) Query: 228 RFYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANEL 276 R M ++ ++PP E++++ ++ E + L R L + QP + NE+ Sbjct: 492 RTSMKIQFKTAMPPTEVLLESIQSKVESIEQLQRKLQQVQPLEQQNNEM 540 >6B44-C nrPDB Length = 344 Score = 28.5 bits (62), Expect = 4.2, Method: Compositional matrix adjust. Identities = 14/34 (41%), Positives = 17/34 (50%), Gaps = 2/34 (5%) Query: 172 SPTSAVAFE--YDPWNKLQHTDYWFENDADAEWP 203 S S +AFE DP + L W + DA EWP Sbjct: 9 STASVLAFERKLDPSDALMSAGAWAQRDASQEWP 42 >5GMK-c nrPDB Length = 587 Score = 27.3 bits (59), Expect = 7.3, Method: Compositional matrix adjust. Identities = 13/49 (26%), Positives = 26/49 (53%) Query: 228 RFYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANEL 276 R M ++ ++PP E++++ ++ E + L R L QP + NE+ Sbjct: 492 RTSMKIQFKTAMPPTEVLLESIQSKVESIEQLQRKLQHVQPLEQQNNEM 540 >2F6U-A nrPDB Length = 234 Score = 27.3 bits (59), Expect = 7.5, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 16/33 (48%), Gaps = 4/33 (12%) Query: 182 DPWNKLQHTDYWFE----NDADAEWPKSKNADW 210 DP N + DY F N AD +W K+A W Sbjct: 70 DPSNVVYDVDYLFVPTVLNSADGDWITGKHAQW 102 >5WQ8-A nrPDB Length = 650 Score = 27.3 bits (59), Expect = 8.2, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 24/45 (53%) Query: 240 PPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEM 284 P N I++ G + +LA ++R +D+ ++ ELN AEM Sbjct: 136 PANIILITGRAAVVNRLAEIIRRVDQAGDKEIEVVELNNASAAEM 180 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3H0G-C nrPDB 462 e-131 5X4Z-C nrPDB 378 e-105 3HOY-C nrPDB 376 e-105 3J0K-C nrPDB 368 e-102 5IYA-C nrPDB 321 2e-88 5LMX-C nrPDB 264 3e-71 6F44-C nrPDB 263 6e-71 2PMZ-D nrPDB 261 3e-70 2WB1-D nrPDB 259 1e-69 4QIW-D nrPDB 214 4e-56 Sequences not found previously or not previously below threshold: 1IW7-A nrPDB 54 8e-08 5ZX3-A nrPDB 53 2e-07 6CCE-A nrPDB 49 3e-06 4YLN-A nrPDB 48 7e-06 4MEY-A nrPDB 47 9e-06 1HQM-A nrPDB 47 9e-06 5V2D-A nrPDB 34 0.079 4OVR-A nrPDB 31 0.61 5KXJ-A nrPDB 29 3.3 6EM8-A nrPDB 29 3.5 >3H0G-C nrPDB Length = 297 Score = 462 bits (1188), Expect = e-131, Method: Composition-based stats. Identities = 297/297 (100%), Positives = 297/297 (100%) Query: 1 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE 60 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE Sbjct: 1 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE 60 Query: 61 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYAR 120 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYAR Sbjct: 61 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYAR 120 Query: 121 DLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFE 180 DLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFE Sbjct: 121 DLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFE 180 Query: 181 YDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIP 240 YDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIP Sbjct: 181 YDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIP 240 Query: 241 PNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEMNWSPYQNGEENTW 297 PNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEMNWSPYQNGEENTW Sbjct: 241 PNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNMEENAEMNWSPYQNGEENTW 297 >5X4Z-C nrPDB Length = 304 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 142/277 (51%), Positives = 203/277 (73%), Gaps = 9/277 (3%) Query: 1 MDSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDE 60 M E + I N + V+ +L++ +L++ANSLRR +LAE+PT+AIDLVEI +NTSV+ DE Sbjct: 1 MSKEPKVNIINAQDDEVELMLSDVNLSLANSLRRTMLAEVPTLAIDLVEIKMNTSVLADE 60 Query: 61 FLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGE-GTMEIYA 119 F++HRLG+IPL S +++E ++Y+R+C C+ YC +CSV L L+A+ GE GT ++Y+ Sbjct: 61 FISHRLGLIPLVSEDVEE-----MKYSRDCTCEDYCDECSVVLELSARHEGEEGTTDVYS 115 Query: 120 RDLVVSS---NSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSA 176 L+ S N ++G P+ D +G L+CKLR QE+++RCIAKKGIAKEHAKWSP SA Sbjct: 116 SSLIKVSGPGNLNVGEPVRRDDYDQGILLCKLRNHQELNIRCIAKKGIAKEHAKWSPCSA 175 Query: 177 VAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESV 236 +AFEYDP NKL+HTD+WFE DA EWP SK A WEEPP+ GE F+++ +P RFYM VE+ Sbjct: 176 IAFEYDPHNKLKHTDFWFEVDAKKEWPDSKYATWEEPPKPGEVFDYKAKPNRFYMTVETT 235 Query: 237 GSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSA 273 GS+ N++ +G++ LQEKLA ++ +L+ +P +A Sbjct: 236 GSLKANQVFSRGIKTLQEKLANVLFELENSRPANTTA 272 >3HOY-C nrPDB Length = 347 Score = 376 bits (966), Expect = e-105, Method: Composition-based stats. Identities = 147/277 (53%), Positives = 207/277 (74%), Gaps = 13/277 (4%) Query: 5 THITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAH 64 + IR SK++VDF+L+N LA+ANSLRRV++AEIPT+AID VE+ NT+V+ DEF+AH Sbjct: 35 PQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLADEFIAH 94 Query: 65 RLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVV 124 RLG+IPL S +I++ LEY+R+C C+ +C KCSV L L A E T +Y++DLV+ Sbjct: 95 RLGLIPLQSMDIEQ-----LEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYSKDLVI 149 Query: 125 SSN---SSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEY 181 SN ++GHPI+ D + G LICKLRK QE+ L C+AKKGIAKEHAKW P +A+ FEY Sbjct: 150 VSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAAIEFEY 209 Query: 182 DPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPP 241 DPWNKL+HTDYW+E D+ EWP+SKN ++E+PP EG+PF+++ + FYM+VESVGSIP Sbjct: 210 DPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESVGSIPV 269 Query: 242 NEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNM 278 ++++V+G+ LQ+K+A ++ L TQ+ +++N Sbjct: 270 DQVVVRGIDTLQKKVASILLAL-----TQMDQDKVNF 301 >3J0K-C nrPDB Length = 268 Score = 368 bits (945), Expect = e-102, Method: Composition-based stats. Identities = 148/278 (53%), Positives = 206/278 (74%), Gaps = 14/278 (5%) Query: 1 MDSE-THITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPD 59 M E + IR SK++VDF+L+N LA+ANSLRRV++AEIPT+AID VE+ NT+V+ D Sbjct: 1 MSEEGPQVKIREASKDNVDFILSNVDLAMANSLRRVMIAEIPTLAIDSVEVETNTTVLAD 60 Query: 60 EFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYA 119 EF+AHRLG+IPL S +I++ LEY+R+C C+ +C KCSV L L A E T +Y+ Sbjct: 61 EFIAHRLGLIPLQSMDIEQ-----LEYSRDCFCEDHCDKCSVVLTLQAFGESESTTNVYS 115 Query: 120 RDLVVSSN---SSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSA 176 +DLV+ SN ++GHPI+ D + G LICKLRK QE+ L C+AKKGIAKEHAKW P +A Sbjct: 116 KDLVIVSNLMGRNIGHPIIQDKEGNGVLICKLRKGQELKLTCVAKKGIAKEHAKWGPAAA 175 Query: 177 VAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESV 236 + FEYDPWNKL+HTDYW+E D+ EWP+SKN ++E+PP EG+PF+++ + FYM+VESV Sbjct: 176 IEFEYDPWNKLKHTDYWYEQDSAKEWPQSKNCEYEDPPNEGDPFDYKAQADTFYMNVESV 235 Query: 237 GSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSAN 274 GSIP ++++V+G+ LQ+K+A ++ L TQ+ + Sbjct: 236 GSIPVDQVVVRGIDTLQKKVASILLAL-----TQMDQD 268 >5IYA-C nrPDB Length = 275 Score = 321 bits (823), Expect = 2e-88, Method: Composition-based stats. Identities = 119/274 (43%), Positives = 174/274 (63%), Gaps = 20/274 (7%) Query: 2 DSETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEF 61 ++ + I ++ +V F++ NT LAVANS+RRV +AE+P +AID V+I+ N+SV+ DEF Sbjct: 4 ANQPTVRITELTDENVKFIIENTDLAVANSIRRVFIAEVPIIAIDWVQIDANSSVLHDEF 63 Query: 62 LAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARD 121 +AHRLG+IPL S +I + L+Y+R+C C+++CP+CSVE L+ +C + T + +RD Sbjct: 64 IAHRLGLIPLISDDIVD----KLQYSRDCTCEEFCPECSVEFTLDVRCNEDQTRHVTSRD 119 Query: 122 LVVSSNSSLGHPILADPKSRGP---------LICKLRKEQEISLRCIAKKGIAKEHAKWS 172 L+ SNS P+ + + P LI KLRK QE+ LR AKKG KEHAKW+ Sbjct: 120 LI--SNSPRVIPVTSRNRDNDPNDYVEQDDILIVKLRKGQELRLRAYAKKGFGKEHAKWN 177 Query: 173 PTSAVAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMD 232 PT+ VAFEYDP N L+HT Y EWPKS+ ++ +E + P++ +P RFY + Sbjct: 178 PTAGVAFEYDPDNALRHTVY----PKPEEWPKSEYSELDEDESQA-PYDPNGKPERFYYN 232 Query: 233 VESVGSIPPNEIMVQGLRILQEKLAVLVRDLDEE 266 VES GS+ P I++ L L++KL+ L L E Sbjct: 233 VESCGSLRPETIVLSALSGLKKKLSDLQTQLSHE 266 >5LMX-C nrPDB Length = 380 Score = 264 bits (675), Expect = 3e-71, Method: Composition-based stats. Identities = 86/319 (26%), Positives = 140/319 (43%), Gaps = 50/319 (15%) Query: 3 SETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFL 62 + + I ++ +F L N ++AN+ RR++++E+P+VA + V NTSV+ DE L Sbjct: 38 KDFEVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVL 97 Query: 63 AHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEG--------- 113 AHR+G++PL +P + + D +++ + ++ L LN KCT Sbjct: 98 AHRIGLVPLKV----DPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDP 153 Query: 114 -----TMEIYARDLVV-----SSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKG 163 +YARDL S + P++ P L+ KLR QEISL+ G Sbjct: 154 KELYNNAHVYARDLKFEPQGRQSTTFADCPVV--PADPDILLAKLRPGQEISLKAHCILG 211 Query: 164 IAKEHAKWSPTSAVAFEYDPW-NKLQ----HTDYWFEN---------DADAEWPKSKNAD 209 I +HAK+SP S ++ P N LQ + F+ D ++ K+A Sbjct: 212 IGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDAR 271 Query: 210 WEEPPRE-------GEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRD 262 + RE + F +VES G++ P EI + +RIL+ K Sbjct: 272 KDTVSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNKAEY---- 327 Query: 263 LDEEQPTQLSANELNMEEN 281 L TQ S + ++N Sbjct: 328 LKNCPITQGSMEKRRWKKN 346 >6F44-C nrPDB Length = 335 Score = 263 bits (672), Expect = 6e-71, Method: Composition-based stats. Identities = 82/297 (27%), Positives = 133/297 (44%), Gaps = 46/297 (15%) Query: 3 SETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFL 62 + + I ++ +F L N ++AN+ RR++++E+P+VA + V NTSV+ DE L Sbjct: 38 KDFEVNISSLDAREANFDLINIDTSIANAFRRIMISEVPSVAAEYVYFFNNTSVIQDEVL 97 Query: 63 AHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEG--------- 113 AHR+G++PL +P + + D +++ + ++ L LN KCT Sbjct: 98 AHRIGLVPLKV----DPDMLTWVDSNLPDDEKFTDENTIVLSLNVKCTRNPDAPKGSTDP 153 Query: 114 -----TMEIYARDLVV-----SSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKG 163 +YARDL S + P++ P L+ KLR QEISL+ G Sbjct: 154 KELYNNAHVYARDLKFEPQGRQSTTFADCPVV--PADPDILLAKLRPGQEISLKAHCILG 211 Query: 164 IAKEHAKWSPTSAVAFEYDPW-NKLQ----HTDYWFEN---------DADAEWPKSKNAD 209 I +HAK+SP S ++ P N LQ + F+ D ++ K+A Sbjct: 212 IGGDHAKFSPVSTASYRLLPQINILQPIKGESARRFQKCFPPGVIGIDEGSDEAYVKDAR 271 Query: 210 WEEPPRE-------GEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVL 259 + RE + F +VES G++ P EI + +RIL+ K L Sbjct: 272 KDTVSREVLRYEEFADKVKLGRVRNHFIFNVESAGAMTPEEIFFKSVRILKNKAEYL 328 >2PMZ-D nrPDB Length = 265 Score = 261 bits (666), Expect = 3e-70, Method: Composition-based stats. Identities = 73/277 (26%), Positives = 118/277 (42%), Gaps = 35/277 (12%) Query: 7 ITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRL 66 I + + +D V L N++RR + +P +A+D V N S + DE LAHRL Sbjct: 3 INLLHKDDTRIDLVFEGYPLEFVNAIRRASMLYVPIMAVDDVYFIENNSPLYDEILAHRL 62 Query: 67 GMIPLDSSNIDEPPPVGLEYTR---NC-DCDQYCPKCSVELFLNAKCTGEGTMEIYARDL 122 +IP S L+ R C +C + C KC ++++ A+ E M IY++D Sbjct: 63 ALIPFMSEE-------ALDTYRWPEECIECTENCEKCYTKIYIEAEAPNEPRM-IYSKD- 113 Query: 123 VVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYD 182 + S PI D I L Q+ISL + G KEHAK+ P S Y Sbjct: 114 -IKSEDPSVVPISGDIP-----IVLLGTNQKISLEARLRLGYGKEHAKFIPVSLSVVRYY 167 Query: 183 P-----------WNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEP---FNFQEEPRR 228 P N + ++ + + EE R +F E+ + Sbjct: 168 PKVEILANCEKAVNVCPEGVFELKDGKLSVKNELSCTLCEECLRYCNGSIRISFVED--K 225 Query: 229 FYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRDLDE 265 + +++ESVGS+ P I+++ + + K+ L + L E Sbjct: 226 YILEIESVGSLKPERILLEAGKSIIRKIEELEKKLVE 262 >2WB1-D nrPDB Length = 265 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 70/275 (25%), Positives = 113/275 (41%), Gaps = 31/275 (11%) Query: 7 ITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHRL 66 I + + +D V L N++RR + +P ++ID V N S + DE LAHRL Sbjct: 3 INLLHKDDKRIDLVFEGYPLEFVNAIRRAAMLYVPVMSIDDVYFIENNSPLYDEILAHRL 62 Query: 67 GMIPLDSSNIDEPPPVGLEYTR---NC-DCDQYCPKCSVELFLNAKCTGEGTMEIYARDL 122 +IP S L+ R C DC + C KC ++++ A+ E M +Y++D Sbjct: 63 ALIPFTSEE-------ALDTYRWPEECIDCTENCEKCYTKIYIEAEALNEPKM-LYSKD- 113 Query: 123 VVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYD 182 + S PI D I L Q+ISL + G KEHAK+ P S Y Sbjct: 114 -IKSEDPSIVPISGDIP-----IVLLGANQKISLEARLRLGYGKEHAKFIPVSLAIVRYY 167 Query: 183 PW-----------NKLQHTDYWFENDADAEWPKSKNADWEEPPREGEP-FNFQEEPRRFY 230 P + ++ + + EE R ++ Sbjct: 168 PKVEILGNCEKGATVCPEGVFELKDGKLSVKNELACTLCEECLRYCNGLIRISSVEDKYI 227 Query: 231 MDVESVGSIPPNEIMVQGLRILQEKLAVLVRDLDE 265 +++ESVGS+ P I+++ + + K+ L + L E Sbjct: 228 LELESVGSLKPERILLEAGKSIIRKIEELEKKLVE 262 >4QIW-D nrPDB Length = 259 Score = 214 bits (544), Expect = 4e-56, Method: Composition-based stats. Identities = 78/278 (28%), Positives = 114/278 (41%), Gaps = 46/278 (16%) Query: 6 HITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFLAHR 65 I +S+ F+++ + AN+LRR +L+E+PT A+D VE N S + DE +AHR Sbjct: 3 EFKILEKRPDSIKFIVSGVDVPFANALRRTILSEVPTFAVDEVEFLENDSALFDEIIAHR 62 Query: 66 LGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDLVVS 125 L MIPL + P + D Y S+E EG +Y+ DL Sbjct: 63 LAMIPLTT-------PHERFSLDALELDDYTVTLSLE--------AEGPGMVYSGDL--- 104 Query: 126 SNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVAFEYDPWN 185 SS G A+P I KL + Q ++ A+ G K+HAKW P F Y + Sbjct: 105 -KSSDGDVKPANPNIP---IVKLAEGQRLTFNAYARLGRGKDHAKWQP----GFVYYKYL 156 Query: 186 KLQHTDYWFEN-DADAEWPKSKNADWEEPPREG---------EPFNFQEE---------- 225 H + + E + + EE E P F+E Sbjct: 157 TKIHVSKDVPDWEELKELAERRGLPVEESDEEIVITTIKAFYLPRKFEEHMGKGIREEIV 216 Query: 226 PRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRDL 263 P F VE+ G +P EI+ L+IL K + +L Sbjct: 217 PGSFVFTVETNGELPVEEIVSIALKILMRKSDRFINEL 254 >1IW7-A nrPDB Length = 315 Score = 54.1 bits (128), Expect = 8e-08, Method: Composition-based stats. Identities = 51/261 (19%), Positives = 90/261 (34%), Gaps = 46/261 (17%) Query: 3 SETHITIRNISKNSVDFVLT----NTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMP 58 T+R + +FVL + + N LRR++L+ IP A+ V I Sbjct: 7 KAPVFTVRTQGREYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYI-------- 58 Query: 59 DEFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIY 118 E + H IP ++ E + P L EG E+ Sbjct: 59 -EDVLHEFSTIPGVKEDVVEIILN----LKELVVRFLNPSLQTVTLL---LKAEGPKEVK 110 Query: 119 ARDLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVA 178 ARD + ++ + +P I L + +++ +G+ + P Sbjct: 111 ARDFLPVADVEIMNP--------DLHIATLEEGGRLNMEVRVDRGVG-----YVPAEKHG 157 Query: 179 FEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGS 238 + D N + D F P + A E R G+ + + + + + GS Sbjct: 158 IK-DRINAIP-VDAVFS-------PVRRVAFQVEDTRLGQRTDL----DKLTLRIWTDGS 204 Query: 239 IPPNEIMVQGLRILQEKLAVL 259 + P E + Q + IL+E L Sbjct: 205 VTPLEALNQAVEILREHLTYF 225 >5ZX3-A nrPDB Length = 368 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 48/285 (16%), Positives = 96/285 (33%), Gaps = 52/285 (18%) Query: 1 MDSETHITIRNISKNSVDFVLT----NTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSV 56 + ++ ++ N FV+ + NSLRR +L+ IP A+ TS+ Sbjct: 24 ISQRPTLSEDVLTDNRSQFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAV--------TSI 75 Query: 57 MPDEFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTME 116 D L H +P ++ E + L+ + + +G E Sbjct: 76 RIDGVL-HEFTTVPGVKEDVTEI-ILNLKSLVVSSEEDEPVTMYLR--------KQGPGE 125 Query: 117 IYARDLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSA 176 + A D+V G + + G I L + ++ + + ++G A + S Sbjct: 126 VTAGDIV----PPAGVTV----HNPGMHIATLNDKGKLEVELVVERGRGYVPAVQNRASG 177 Query: 177 VAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESV 236 P + + P K + R + +F + +DVE+ Sbjct: 178 AEIGRIPVDSIYS-------------PVLKVTYKVDATRVEQRTDF----DKLILDVETK 220 Query: 237 GSIPPNEIMVQGLRILQE-----KLAVLVRDLDEEQPTQLSANEL 276 SI P + + + L E + + + E P+ A+ + Sbjct: 221 NSISPRDALASAGKTLVELFGLARELNVEAEGIEIGPSPAEADHI 265 >6CCE-A nrPDB Length = 350 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 46/258 (17%), Positives = 88/258 (34%), Gaps = 47/258 (18%) Query: 1 MDSETHITIRNISKNSVDFVLT----NTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSV 56 + ++ +++N FV+ + NSLRR +L+ IP A+ TS+ Sbjct: 3 ISQRPTLSEETVAENRSRFVIEPLEPGFGYTLGNSLRRTLLSSIPGAAV--------TSI 54 Query: 57 MPDEFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTME 116 D L H +P ++ + + D D+ V ++L +G Sbjct: 55 RIDGVL-HEFTTVPGVKEDVTDIILNLKGLVVSSDDDE-----PVTMYLR----KQGPGV 104 Query: 117 IYARDLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSA 176 + A D+V G + + I L + ++ + + ++G A + S Sbjct: 105 VTAGDIV----PPAGVTV----HNPDMHIATLNDKGKLEVELVVERGRGYVPAVQNKASG 156 Query: 177 VAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESV 236 P + + P K E R + +F + +DVE+ Sbjct: 157 AEIGRIPVDSIYS-------------PVLKVTYKVEATRVEQRTDF----DKLIIDVETK 199 Query: 237 GSIPPNEIMVQGLRILQE 254 SI P + + L E Sbjct: 200 NSISPRDALASAGGTLVE 217 >4YLN-A nrPDB Length = 242 Score = 47.5 bits (111), Expect = 7e-06, Method: Composition-based stats. Identities = 48/264 (18%), Positives = 88/264 (33%), Gaps = 55/264 (20%) Query: 7 ITIRNISKNSVDFVLT----NTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFL 62 + I +S L + N+LRR++L+ +P A+ VEI V+ + Sbjct: 21 VDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEI---DGVLHE--- 74 Query: 63 AHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDL 122 + + + + + K V L LN G + A D+ Sbjct: 75 --------YSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLN----KSGIGPVTAADI 122 Query: 123 VVSSNSSLGHPILADPKSRGPLICKLR-KEQEISLRCIAKKGIAKEHAKWSPTSAVAFEY 181 + + P +IC L + IS+R ++G Y Sbjct: 123 THDGDVEIVKP--------QHVICHLTDENASISMRIKVQRGRG---------------Y 159 Query: 182 DPWNKLQHTDYWFENDADAEWPKSKNADWEEPPR-----EGEPFNFQEEPRRFYMDVESV 236 P + H+ E D +A + R E + + + +++E+ Sbjct: 160 VPASTRIHS----EEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETN 215 Query: 237 GSIPPNEIMVQGLRILQEKLAVLV 260 G+I P E + + IL E+L V Sbjct: 216 GTIDPEEAIRRAATILAEQLEAFV 239 >4MEY-A nrPDB Length = 335 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 50/283 (17%), Positives = 96/283 (33%), Gaps = 56/283 (19%) Query: 7 ITIRNISKNSVDFVLT----NTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFL 62 + I +S L + N+LRR++L+ +P A+ VEI V+ + Sbjct: 20 VDIEQVSSTHAKVTLEPLERGFGHTLGNALRRILLSSMPGCAVTEVEI---DGVLHE--- 73 Query: 63 AHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIYARDL 122 + + + + + K V L LN G + A D+ Sbjct: 74 --------YSTKEGVQEDILEILLNLKGLAVRVQGKDEVILTLN----KSGIGPVTAADI 121 Query: 123 VVSSNSSLGHPILADPKSRGPLICKLR-KEQEISLRCIAKKGIAKEHAKWSPTSAVAFEY 181 + + P +IC L + IS+R ++G Y Sbjct: 122 THDGDVEIVKP--------QHVICHLTDENASISMRIKVQRGRG---------------Y 158 Query: 182 DPWNKLQHTDYWFENDADAEWPKSKNADWEEPPR-----EGEPFNFQEEPRRFYMDVESV 236 P + H+ E D +A + R E + + + +++E+ Sbjct: 159 VPASTRIHS----EEDERPIGRLLVDACYSPVERIAYNVEAARVEQRTDLDKLVIEMETN 214 Query: 237 GSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLSANELNME 279 G+I P E + + IL E+L V DL + + ++ + + Sbjct: 215 GTIDPEEAIRRAATILAEQLEAFV-DLRDVRQPEVKEEKPEFD 256 >1HQM-A nrPDB Length = 313 Score = 47.1 bits (110), Expect = 9e-06, Method: Composition-based stats. Identities = 54/271 (19%), Positives = 92/271 (33%), Gaps = 47/271 (17%) Query: 3 SETHITIRNISKNSVDFVLT----NTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMP 58 T + +FVL + + N LRR++L+ IP A+ V I Sbjct: 7 KAPVFTATTQGDHYGEFVLEPLERGFGVTLGNPLRRILLSSIPGTAVTSVYI-------- 58 Query: 59 DEFLAHRLGMIPLDSSNIDEPPPVGLEYTRNCDCDQYCPKCSVELFLNAKCTGEGTMEIY 118 E + H IP ++ E + P+ L L A EG E+ Sbjct: 59 -EDVLHEFSTIPGVKEDVVEIILN----LKELVVRFLDPRWRTTLILRA----EGPKEVR 109 Query: 119 ARDLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISLRCIAKKGIAKEHAKWSPTSAVA 178 A D S++ + +P I L + ++ + +G+ + P Sbjct: 110 AVDFTPSADVEIMNP--------DLHIATLEEGGKLYMEVRVDRGVG-----YVPAERHG 156 Query: 179 FEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGS 238 + D N + D F P + A E R G+ + + + + + GS Sbjct: 157 IK-DRINAIP-VDAIFS-------PVRRVAFQVEDTRLGQRTDL----DKLTLRIWTDGS 203 Query: 239 IPPNEIMVQGLRILQEKLAVLVRDLDEEQPT 269 + P E + Q + IL+E L PT Sbjct: 204 VTPLEALNQAVAILKEHLNYFANPEASLLPT 234 >5V2D-A nrPDB Length = 501 Score = 34.0 bits (76), Expect = 0.079, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 36/112 (32%), Gaps = 5/112 (4%) Query: 161 KKGIAKEHAKWSPTSAVAFEYDPWNKLQHTDYWFENDADAEWPKSKNADWEEPPREGEPF 220 + H +W P F P N WF+ D + NA E+ + Sbjct: 261 RMKNGGPHFQWQPDLPQLFAVVPRNGRAQDVRWFKGPMDGFQGHTLNAFDEDGKVYVDM- 319 Query: 221 NFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKLAVLVRDLDEEQPTQLS 272 FY ++ G +PP E + L L DE +P L+ Sbjct: 320 -PVTGGNIFYFFPQADGHVPPPETLAAC---LMRWTFDLNSGRDEVEPQPLT 367 >4OVR-A nrPDB Length = 322 Score = 31.0 bits (68), Expect = 0.61, Method: Composition-based stats. Identities = 13/59 (22%), Positives = 25/59 (42%) Query: 4 ETHITIRNISKNSVDFVLTNTSLAVANSLRRVVLAEIPTVAIDLVEINVNTSVMPDEFL 62 E + +R +KNSV ++ +S +V A + + ID + D+F+ Sbjct: 248 EEQVQVRKAAKNSVGYMRQLWDAMEISSREKVEKAGVEVITIDKAPFQAAVQPLYDQFV 306 >5KXJ-A nrPDB Length = 557 Score = 28.7 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 26/54 (48%) Query: 203 PKSKNADWEEPPREGEPFNFQEEPRRFYMDVESVGSIPPNEIMVQGLRILQEKL 256 P+++N E R + + + RF DV+ G + P +I+ + + ++L Sbjct: 251 PQARNFLLTEALRGEGAYLKRPDGSRFMPDVDERGELAPRDIVARAIDHEMKQL 304 >6EM8-A nrPDB Length = 818 Score = 28.7 bits (62), Expect = 3.5, Method: Composition-based stats. Identities = 16/70 (22%), Positives = 30/70 (42%) Query: 97 PKCSVELFLNAKCTGEGTMEIYARDLVVSSNSSLGHPILADPKSRGPLICKLRKEQEISL 156 P+ S + +K T++ ARDL V + P++ K +I L + + + Sbjct: 145 PEMSNKNAQASKSNNTPTLDSLARDLTVIAKDGTLDPVIGRDKEITRVIEVLSRRTKNNP 204 Query: 157 RCIAKKGIAK 166 I + G+ K Sbjct: 205 VLIGEPGVGK 214 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.303 0.120 0.301 Lambda K H 0.267 0.0372 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,827,626 Number of Sequences: 36641 Number of extensions: 356184 Number of successful extensions: 798 Number of sequences better than 10.0: 21 Number of HSP's better than 10.0 without gapping: 31 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 717 Number of HSP's gapped (non-prelim): 49 length of query: 297 length of database: 10,336,785 effective HSP length: 96 effective length of query: 201 effective length of database: 6,819,249 effective search space: 1370669049 effective search space used: 1370669049 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.4 bits) S2: 58 (27.1 bits)