BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P36959 (345 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2BWG-A nrPDB 713 0.0 2C6Q-A nrPDB 573 e-164 3R2G-A nrPDB 210 6e-55 4MJM-A nrPDB 204 4e-53 5UQG-A nrPDB 194 4e-50 1VRD-A nrPDB 193 9e-50 4FEZ-A nrPDB 182 2e-46 3TSB-A nrPDB 178 3e-45 4QJ1-A nrPDB 178 3e-45 1EEP-A nrPDB 171 3e-43 3FFS-A nrPDB 168 4e-42 1ZFJ-A nrPDB 166 1e-41 1YPF-A nrPDB 164 4e-41 4FXS-A nrPDB 159 1e-39 5AHL-A nrPDB 158 4e-39 2CU0-A nrPDB 144 5e-35 4DQW-A nrPDB 142 2e-34 5UPU-A nrPDB 140 8e-34 4XTI-A nrPDB 132 1e-31 4Z87-A nrPDB 127 1e-29 6I0M-A nrPDB 124 9e-29 4AF0-B nrPDB 122 2e-28 1JCN-A nrPDB 118 4e-27 1AK5-A nrPDB 87 1e-17 1RI1-A nrPDB 33 0.14 1NF4-A nrPDB 32 0.45 1TYG-A nrPDB 28 5.2 1J5S-A nrPDB 28 6.2 3AK5-A nrPDB 28 7.8 >2BWG-A nrPDB Length = 367 Score = 713 bits (1841), Expect = 0.0, Method: Compositional matrix adjust. Identities = 344/345 (99%), Positives = 344/345 (99%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT Sbjct: 23 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 82 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 120 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV Sbjct: 83 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 142 Query: 121 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 180 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV Sbjct: 143 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 202 Query: 181 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 240 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM Sbjct: 203 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 262 Query: 241 LGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD 300 LGGMFSGHTECAGEV ERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD Sbjct: 263 LGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD 322 Query: 301 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 345 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS Sbjct: 323 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 367 >2C6Q-A nrPDB Length = 351 Score = 573 bits (1477), Expect = e-164, Method: Compositional matrix adjust. Identities = 267/332 (80%), Positives = 304/332 (91%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 LDFKDVLLRPKRS+LKSR+EVDL R+F+FRNSKQTYSG+PII ANMDTVGTFEMA V+ + Sbjct: 20 LDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLCK 79 Query: 70 HSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLD 129 S+FTA+HKHYSL W+ FA +P+CL+++A SSG+G +D E++ ILEA+PQVK+ICLD Sbjct: 80 FSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICLD 139 Query: 130 VANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTR 189 VANGYSEHFVEFVK VR +FP+HTIMAGNVVTGEMVEELILSGADIIKVG+GPGSVCTTR Sbjct: 140 VANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTTR 199 Query: 190 TKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHT 249 KTGVGYPQLSAV+ECAD+AHGLKGHIISDGGC+CPGDVAKAFGAGADFVMLGGM +GH+ Sbjct: 200 KKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGHS 259 Query: 250 ECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDIL 309 E GE+ ER+G+K KLFYGMSS+ AM K+AGGVAEYRASEGKTVEVP+KGDVE+TI DIL Sbjct: 260 ESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDIL 319 Query: 310 GGLRSTCTYVGAAKLKELSRRATFIRVTQQHN 341 GG+RSTCTYVGAAKLKELSRR TFIRVTQQ N Sbjct: 320 GGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN 351 >3R2G-A nrPDB Length = 361 Score = 210 bits (535), Expect = 6e-55, Method: Compositional matrix adjust. Identities = 127/333 (38%), Positives = 188/333 (56%), Gaps = 13/333 (3%) Query: 7 DLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAV 66 D + F DVLL P + +SR V E T T R K T + +P+I ANMDT+ MA Sbjct: 5 DQAITFDDVLLVPSYNHHESRRVV--ETTSTDRLGKLTLN-LPVISANMDTITESNMANF 61 Query: 67 MSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFI 126 M A+H+ ++++ +C V VS G +N+L++ ++ +A F Sbjct: 62 MHSKGAMGALHRFMTIEEN---IQEFKKCKGPVFVSVGCTENELQRAEALRDA--GADFF 116 Query: 127 CLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVC 186 C+DVA+ ++++ + +K +R IMAGNV T + L GADIIK G+G GSVC Sbjct: 117 CVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVATYAGADYLASCGADIIKAGIGGGSVC 176 Query: 187 TTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFS 246 +TR KTG G P L+ + +C+ + I++DGG GD+ KA GADFVM+GGM + Sbjct: 177 STRIKTGFGVPMLTCIQDCSRADR----SIVADGGIKTSGDIVKALAFGADFVMIGGMLA 232 Query: 247 GHTECAGEVFER-NGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTI 305 G GEVF++ +G K+K + GM+S A G + E++ +EG EVP+K + + I Sbjct: 233 GSAPTPGEVFQKDDGSKVKRYRGMASREAQEAFLGQMHEWKTAEGVATEVPFKENPDGII 292 Query: 306 LDILGGLRSTCTYVGAAKLKELSRRATFIRVTQ 338 DI+GGLRS TY GA + EL R+ ++ VTQ Sbjct: 293 ADIIGGLRSGLTYAGADSISELQRKLNYVIVTQ 325 >4MJM-A nrPDB Length = 385 Score = 204 bits (519), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 140/365 (38%), Positives = 187/365 (51%), Gaps = 53/365 (14%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L F DVLL P +S + R EV ++ S+ IP+I A MDTV +MA M++ Sbjct: 14 LTFDDVLLVPAKSDVLPR-EVSVKTVL----SESLQLNIPLISAGMDTVTEADMAIAMAR 68 Query: 70 HSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEK----------------- 112 IHK+ S++ E + V S G D+EK Sbjct: 69 QGGLGIIHKNMSIE-------QQAEQVDKVKRSESGGIKDIEKVIEFPNSAKDKQGRLLV 121 Query: 113 ----------MTSILEAV-PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVT 161 MT I V V I LD A+G+S+ ++ VK VRAK+P I+AGNV T Sbjct: 122 GAAVGVTADAMTRIDALVKASVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVAT 181 Query: 162 GEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSA--HGLKGHIISD 219 E + LI +GA+++KVG+GPGS+CTTR GVG PQL+AV +CA A HG+ +I+D Sbjct: 182 AEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIP--VIAD 239 Query: 220 GGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHA 279 GG GD+ KA AGA VMLG MF+G E GE GR+ K++ GM S AM K Sbjct: 240 GGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEK-- 297 Query: 280 GGVAEY-------RASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRAT 332 G Y EG VPYKG + +T+ ++GGLR+ Y GA L+ L A Sbjct: 298 GSKDRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQ 357 Query: 333 FIRVT 337 FIR++ Sbjct: 358 FIRMS 362 >5UQG-A nrPDB Length = 406 Score = 194 bits (493), Expect = 4e-50, Method: Compositional matrix adjust. Identities = 119/356 (33%), Positives = 184/356 (51%), Gaps = 35/356 (9%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L F+DVLLRP S + + EV + T K +P+I A MDTV A +M++ Sbjct: 32 LTFEDVLLRPGYSEVLPK-EVKIHTKLT----KNITLNMPLISAAMDTVTEHRAAIMMAR 86 Query: 70 HSMFTAIHKHYS---------------------LDDWKLFATNHPECLQNVAVSSGSGQN 108 IHK+ L K + + + + V + G Sbjct: 87 LGGLGVIHKNMDIASQVREVKRVKKSESGGIKDLKKRKEYPDANKDNFGRLRVGAAIGVG 146 Query: 109 DLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEEL 168 ++++ +++EA V + LD A+G+S+ ++ VK ++AK+P ++AGN+ T + L Sbjct: 147 QMDRVDALVEA--GVDVVVLDSAHGHSKGIIDTVKAIKAKYPNLDLIAGNIATAAAAKAL 204 Query: 169 ILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDV 228 +G D +KVG+GPGS+CTTR +GVG PQ+SA+ EC + A+ +I+DGG GD+ Sbjct: 205 CEAGVDAVKVGIGPGSICTTRIVSGVGVPQISAIDECVEEANKFGVPVIADGGIKYSGDI 264 Query: 229 AKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNK-------HAGG 281 AKA GA VM+G + +G E GE+F GR+ K + GM S AM K G Sbjct: 265 AKALAVGASSVMIGSLLAGTDESPGELFTYQGRQYKSYRGMGSLGAMQKGSSDRYFQQGT 324 Query: 282 VAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 + EG VPY G + + + +LGGLRS+ YVGA +++ +RA F+ +T Sbjct: 325 AQDKLVPEGIEGRVPYVGSIRSVVHQLLGGLRSSMGYVGAKDIEDFQKRAEFVEIT 380 >1VRD-A nrPDB Length = 494 Score = 193 bits (491), Expect = 9e-50, Method: Compositional matrix adjust. Identities = 117/349 (33%), Positives = 185/349 (53%), Gaps = 41/349 (11%) Query: 3 RIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFE 62 R + +L KD L+ P+ + + ++ LE+ + + +P++ + VG Sbjct: 148 RFEKNLSKKIKD-LMTPREKLIVAPPDISLEKAKEILH-QHRIEKLPLVSKDNKLVGLIT 205 Query: 63 MAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQN------VAVSSGSGQNDLEKMTSI 116 + +MS HP ++ V + G+ +E++ + Sbjct: 206 IKDIMS--------------------VIEHPNAARDEKGRLLVGAAVGTSPETMERVEKL 245 Query: 117 LEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADII 176 ++A V I +D A+G+S +E +++++A +P+ ++AGNV T E E LI +GAD + Sbjct: 246 VKA--GVDVIVIDTAHGHSRRVIETLEMIKADYPDLPVVAGNVATPEGTEALIKAGADAV 303 Query: 177 KVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGA 236 KVGVGPGS+CTTR GVG PQL+AV+EC++ A II+DGG GD+ KA AGA Sbjct: 304 KVGVGPGSICTTRVVAGVGVPQLTAVMECSEVARKYDVPIIADGGIRYSGDIVKALAAGA 363 Query: 237 DFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKT---- 292 + VM+G +F+G E GE GRK K + GM S AM G A+ EG+ Sbjct: 364 ESVMVGSIFAGTEEAPGETILYQGRKYKAYRGMGSLGAMR---SGSADRYGQEGENKFVP 420 Query: 293 --VE--VPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 +E VPYKG V++ + ++GGLRS Y+GA +KEL +A F+++T Sbjct: 421 EGIEGMVPYKGTVKDVVHQLVGGLRSGMGYIGARTIKELQEKAVFVKIT 469 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 5/75 (6%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L F DVLL P+ S + + + R ++Q IP++ A MDTV +A +++ Sbjct: 17 LTFDDVLLVPQYSEVLPK-----DVKIDTRLTRQIRINIPLVSAAMDTVTEAALAKALAR 71 Query: 70 HSMFTAIHKHYSLDD 84 IHK+ + D+ Sbjct: 72 EGGIGIIHKNLTPDE 86 >4FEZ-A nrPDB Length = 388 Score = 182 bits (461), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 123/369 (33%), Positives = 188/369 (50%), Gaps = 42/369 (11%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRN--SKQTYSGIPIIVANMDTV 58 M RI A L F DVLL P S++ L T R +K IP++ A+MDTV Sbjct: 6 MLRI-AKEALTFDDVLLVPAHSTV-------LPNTADLRTRLTKNIALNIPMVSASMDTV 57 Query: 59 GTFEMAAVMSQHSMFTAIHKHYSLDDW-------KLF----------ATNHPECLQN--- 98 +A ++Q IHK+ S++ K+F A + P ++ Sbjct: 58 TEARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKIFESGGAKDFHKAESKPNACKDEQG 117 Query: 99 ---VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIM 155 V + G+ + E++ +++EA V + +D ++G+SE ++ ++ RA +P I+ Sbjct: 118 RLRVGAAVGAAPGNEERVKALVEA--GVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEII 175 Query: 156 AGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGH 215 GNV T E LI +G +KVG+GPGS+CTTR TGVG PQ++A+ + A A+ Sbjct: 176 GGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIP 235 Query: 216 IISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAM 275 +I+DGG GD++KA AGA VM+G MF+G E GEV GR K + GM S AM Sbjct: 236 VIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAM 295 Query: 276 NK-------HAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELS 328 +K A+ EG + YKG ++ I +GGLRS G+A +++L Sbjct: 296 SKGSSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLR 355 Query: 329 RRATFIRVT 337 +A F+R++ Sbjct: 356 TKAQFVRIS 364 >3TSB-A nrPDB Length = 511 Score = 178 bits (451), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 105/248 (42%), Positives = 147/248 (59%), Gaps = 15/248 (6%) Query: 99 VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGN 158 V + G + + ++ ++++A V I LD A+G+S+ ++ VK VRAK+P I+AGN Sbjct: 247 VGAAVGVTADAMTRIDALVKA--SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGN 304 Query: 159 VVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSA--HGLKGHI 216 V T E + LI +GA+++KVG+GPGS+CTTR GVG PQL+AV +CA A HG+ + Sbjct: 305 VATAEATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIP--V 362 Query: 217 ISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMN 276 I+DGG GD+ KA AGA VMLG MF+G E GE GR+ K++ GM S AM Sbjct: 363 IADGGIKYSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAME 422 Query: 277 KHAGGVAEY-------RASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSR 329 K G Y EG VPYKG + +T+ ++GGLR+ Y GA L+ L Sbjct: 423 K--GSKDRYFQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRE 480 Query: 330 RATFIRVT 337 A FIR++ Sbjct: 481 NAQFIRMS 488 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/74 (36%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L F DVLL P +S + R EV ++ S+ IP+I A MDTV +MA M++ Sbjct: 35 LTFDDVLLVPAKSDVLPR-EVSVKTVL----SESLQLNIPLISAGMDTVTEADMAIAMAR 89 Query: 70 HSMFTAIHKHYSLD 83 IHK+ S++ Sbjct: 90 QGGLGIIHKNMSIE 103 >4QJ1-A nrPDB Length = 361 Score = 178 bits (451), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 121/338 (35%), Positives = 182/338 (53%), Gaps = 22/338 (6%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L F+D+LL P S + R EV LE T K IP+I + MDTV MA M++ Sbjct: 13 LTFEDILLVPNYSEVLPR-EVSLETKLT----KNVSLKIPLISSAMDTVTEHLMAVGMAR 67 Query: 70 HSMFTAIHKHYSLDDWKLFATNHPECLQN---VAVSSGSGQNDLEKMTSILEAVPQVKFI 126 IHK+ ++ N ++N + V + G N++E+ ++EA V I Sbjct: 68 LGGIGIIHKNMDMESQ----VNEVLKVKNSGGLRVGAAIGVNEIERAKLLVEA--GVDVI 121 Query: 127 CLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVC 186 LD A+G+S + + +K +++K ++ GNVVT E +ELI +GAD IKVG+GPGS+C Sbjct: 122 VLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSIC 180 Query: 187 TTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFS 246 TTR GVG PQ++A+ +C+ A II+DGG GD+ KA GA VM+G + + Sbjct: 181 TTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILA 240 Query: 247 GHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGG--VAEYR-----ASEGKTVEVPYKG 299 G E GE K + GM S AM +G E R EG V YKG Sbjct: 241 GTEESPGEKELIGDTVYKYYRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKYKG 300 Query: 300 DVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 ++E + ++GGLRS Y+G+A ++EL ++++++ +T Sbjct: 301 EMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEIT 338 >1EEP-A nrPDB Length = 404 Score = 171 bits (434), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 122/396 (30%), Positives = 186/396 (46%), Gaps = 65/396 (16%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 MP L F DV L P++SS+ +EV L+ T K IP + + MDTV Sbjct: 1 MPNKITKEALTFDDVSLIPRKSSVLP-SEVSLKTQLT----KNISLNIPFLSSAMDTVTE 55 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDW-------------KLFATN------HPEC------ 95 +MA +++ IHK+ S++ K TN PE Sbjct: 56 SQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKVKTYKFQKTINTNGDTNEQKPEIFTAKQH 115 Query: 96 ----------------------LQNVAVSSGSGQNDLEKMTSILEAV-PQVKFICLDVAN 132 L N + D++ + + E V V + +D A+ Sbjct: 116 LEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSIDIDTIERVEELVKAHVDILVIDSAH 175 Query: 133 GYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKT 192 G+S +E +K ++ K+P ++AGN+VT E +LI GAD +KVG+GPGS+CTTR Sbjct: 176 GHSTRIIELIKKIKTKYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRIVA 235 Query: 193 GVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECA 252 GVG PQ++A+ + ++ + II+DGG GDV KA AGAD VM+G +F+G E Sbjct: 236 GVGVPQITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKESP 295 Query: 253 GEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEY----------RASEGKTVEVPYKGDVE 302 E NG+K K + GM S +AM + G + Y EG VPY G ++ Sbjct: 296 SEEIIYNGKKFKSYVGMGSISAMKR--GSKSRYFQLENNEPKKLVPEGIEGMVPYSGKLK 353 Query: 303 NTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQ 338 + + + GGL S Y+GAA + +L + F++++ Sbjct: 354 DILTQLKGGLMSGMGYLGAATISDLKINSKFVKISH 389 >3FFS-A nrPDB Length = 400 Score = 168 bits (425), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 125/376 (33%), Positives = 186/376 (49%), Gaps = 56/376 (14%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L F+D+LL P S + R EV LE T K IP+I + MDTV MA M++ Sbjct: 10 LTFEDILLVPNYSEVLPR-EVSLETKLT----KNVSLKIPLISSAMDTVTEHLMAVGMAR 64 Query: 70 HSMFTAIHKHYSLD--------------------------------DWKLFATNHP---- 93 IHK+ ++ D K +N+ Sbjct: 65 LGGIGIIHKNMDMESQVNEVLKVKNWISNLEKNESTPDQNLDKESTDGKDTKSNNNIDAY 124 Query: 94 --ECLQN---VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAK 148 E L N + V + G N++E+ ++EA V I LD A+G+S + + +K +++K Sbjct: 125 SNENLDNKGRLRVGAAIGVNEIERAKLLVEA--GVDVIVLDSAHGHSLNIIRTLKEIKSK 182 Query: 149 FPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADS 208 ++ GNVVT E +ELI +GAD IKVG+GPGS+CTTR GVG PQ++A+ +C+ Sbjct: 183 M-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQITAIEKCSSV 241 Query: 209 AHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYG 268 A II+DGG GD+ KA GA VM+G + +G E GE K + G Sbjct: 242 ASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIGDTVYKYYRG 301 Query: 269 MSSDTAMNKHAGG--VAEYRAS-----EGKTVEVPYKGDVENTILDILGGLRSTCTYVGA 321 M S AM +G E R EG V YKG++E + ++GGLRS Y+G+ Sbjct: 302 MGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGLRSCMGYLGS 361 Query: 322 AKLKELSRRATFIRVT 337 A ++EL ++++++ +T Sbjct: 362 ASIEELWKKSSYVEIT 377 >1ZFJ-A nrPDB Length = 491 Score = 166 bits (421), Expect = 1e-41, Method: Compositional matrix adjust. Identities = 96/247 (38%), Positives = 134/247 (54%), Gaps = 10/247 (4%) Query: 99 VAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGN 158 VA + G + E+ ++ EA I +D A+G+S + + +RA FP T++AGN Sbjct: 224 VAAAVGVTSDTFERAEALFEA--GADAIVIDTAHGHSAGVLRKIAEIRAHFPNRTLIAGN 281 Query: 159 VVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIIS 218 + T E L +G D++KVG+GPGS+CTTR GVG PQ++A+ + A A II+ Sbjct: 282 IATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQVTAIYDAAAVAREYGKTIIA 341 Query: 219 DGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKH 278 DGG GD+ KA AG + VMLG MF+G E GE GRK K + GM S AM K Sbjct: 342 DGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQGRKYKTYRGMGSIAAMKKG 401 Query: 279 A------GGVAEYR--ASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRR 330 + G V E EG V YKG + + +LGG+RS YVGA ++EL Sbjct: 402 SSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGGIRSGMGYVGAGDIQELHEN 461 Query: 331 ATFIRVT 337 A F+ ++ Sbjct: 462 AQFVEMS 468 Score = 37.0 bits (84), Expect = 0.014, Method: Compositional matrix adjust. Identities = 26/73 (35%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Query: 12 FKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHS 71 F DVLL P S + EVDL+ + IPII A MDTV +MA +++ Sbjct: 14 FDDVLLIPAESHVLPN-EVDLKTKL----ADNLTLNIPIITAAMDTVTGSKMAIAIARAG 68 Query: 72 MFTAIHKHYSLDD 84 IHK+ S+ + Sbjct: 69 GLGVIHKNMSITE 81 >1YPF-A nrPDB Length = 336 Score = 164 bits (416), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 105/338 (31%), Positives = 182/338 (53%), Gaps = 22/338 (6%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 D++D+ L P + + SR+E D T K +P++ ANM T+ +A +++ Sbjct: 14 FDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFK-----LPVVPANMQTIIDERIATYLAE 68 Query: 70 HSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLD 129 ++ F +H+ + + F + ++S G +++ E + + ++I +D Sbjct: 69 NNYFYIMHR-FQPEKRISFIRDMQSRGLIASISVGVKEDEYEFVQQLAAEHLTPEYITID 127 Query: 130 VANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTR 189 +A+G+S + ++ ++ PE ++AGNV T E V EL +GAD KVG+GPG VC T+ Sbjct: 128 IAHGHSNAVINMIQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITK 187 Query: 190 TKTGVGY--PQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSG 247 KTG G QL+A+ CA +A II+DGG GDVAK+ GA VM+G +F+G Sbjct: 188 IKTGFGTGGWQLAALRWCAKAA---SKPIIADGGIRTNGDVAKSIRFGATMVMIGSLFAG 244 Query: 248 HTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILD 307 H E GE E++G+ K ++G +S+ E + EGK + V +KG +E+T+++ Sbjct: 245 HEESPGETIEKDGKLYKEYFGSASEFQK-------GEKKNVEGKKMFVEHKGSLEDTLIE 297 Query: 308 ILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 345 + L+S+ +Y G KL + R ++ V N++F+ Sbjct: 298 MEQDLQSSISYAGGTKLDSI-RTVDYVVVK---NSIFN 331 >4FXS-A nrPDB Length = 496 Score = 159 bits (403), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 96/273 (35%), Positives = 148/273 (54%), Gaps = 11/273 (4%) Query: 72 MFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVA 131 M TA K + + K A + V + G+ + E++ +++EA V + +D + Sbjct: 197 MITA--KDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEA--GVDVLLIDSS 252 Query: 132 NGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTK 191 +G+SE ++ ++ RA +P I+ GNV T E LI +G +KVG+GPGS+CTTR Sbjct: 253 HGHSEGVLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIV 312 Query: 192 TGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 TGVG PQ++A+ + A A+ +I+DGG GD++KA AGA VM+G MF+G E Sbjct: 313 TGVGVPQITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEA 372 Query: 252 AGEVFERNGRKLKLFYGMSSDTAMNK-------HAGGVAEYRASEGKTVEVPYKGDVENT 304 GEV GR K + GM S AM+K A+ EG + YKG ++ Sbjct: 373 PGEVILYQGRSYKAYRGMGSLGAMSKGSSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEI 432 Query: 305 ILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 I +GGLRS G+A +++L +A F+R++ Sbjct: 433 IHQQMGGLRSCMGLTGSATVEDLRTKAQFVRIS 465 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 31/85 (36%), Positives = 43/85 (50%), Gaps = 6/85 (7%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI A L F DVLL P S++ DL RT R +K IP++ A+MDTV Sbjct: 3 MLRI-AKEALTFDDVLLVPAHSTVLPNT-ADL-RT---RLTKNIALNIPMVSASMDTVTE 56 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDW 85 +A ++Q IHK+ S++ Sbjct: 57 ARLAIALAQEGGIGFIHKNMSIEQQ 81 >5AHL-A nrPDB Length = 400 Score = 158 bits (399), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 120/364 (32%), Positives = 185/364 (50%), Gaps = 35/364 (9%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI + L F DVLL P S + + +V L+ T + IP++ A MDTV Sbjct: 21 MLRISQE-ALTFDDVLLIPGYSEVLPK-DVSLKTRLT----RGIELNIPLVSAAMDTVTE 74 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKL-----------------FATNHPECLQNVAVSS 103 +A M+Q IHK+ ++ A+ + V + Sbjct: 75 ARLAIAMAQEGGIGIIHKNMGIEQQAAEVRKVKKHETAKAKTYPLASKDEQGRLRVGAAV 134 Query: 104 GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGE 163 G+G + E++ +++ A V + +D A+G+S+ +E V+ V+ FP+ ++ GN+ T E Sbjct: 135 GTGADTGERVAALVAA--GVDVVVVDTAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAE 192 Query: 164 MVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCT 223 + L +GAD +KVG+GPGS+CTTR GVG PQ+SA+ A + G +I+DGG Sbjct: 193 AAKALAEAGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIR 252 Query: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMN------- 276 GD+AKA AGA VM+G MF+G E GE+ GR K + GM S AM+ Sbjct: 253 FSGDLAKAMVAGAYCVMMGSMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSD 312 Query: 277 ---KHAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATF 333 + A AE EG VPYKG + + ++GGLR+ Y G+A ++++ + F Sbjct: 313 RYFQDASAGAEKLVPEGIEGRVPYKGALSAIVHQLMGGLRAAMGYTGSADIQQMRTQPQF 372 Query: 334 IRVT 337 +R+T Sbjct: 373 VRIT 376 >2CU0-A nrPDB Length = 486 Score = 144 bits (364), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 85/224 (37%), Positives = 125/224 (55%), Gaps = 11/224 (4%) Query: 123 VKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGP 182 V I +D A+ ++ ++ +K +R K + + GN+ + V++L AD +KVG+GP Sbjct: 241 VDVIVVDTAHAHNLKAIKSMKEMRQKV-DADFIVGNIANPKAVDDLTF--ADAVKVGIGP 297 Query: 183 GSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLG 242 GS+CTTR GVG PQ++AV AD A ++I+DGG GD+ KA AGAD VMLG Sbjct: 298 GSICTTRIVAGVGVPQITAVAMVADRAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLG 357 Query: 243 GMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNK------HAGGVAEYR--ASEGKTVE 294 + +G E G+ NGRK K + GM S AM K + GG + R EG Sbjct: 358 NLLAGTKEAPGKEVIINGRKYKQYRGMGSLGAMMKGGAERYYQGGYMKTRKFVPEGVEGV 417 Query: 295 VPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQ 338 VPY+G V + ++GGL++ YVGA ++EL + F+ +T Sbjct: 418 VPYRGTVSEVLYQLVGGLKAGMGYVGARNIRELKEKGEFVIITH 461 Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 23/73 (31%), Positives = 41/73 (56%), Gaps = 5/73 (6%) Query: 12 FKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHS 71 F DVLL P+ + ++ + +VD+ + R + IPI+ A MDTV +EMA M++ Sbjct: 17 FDDVLLIPQATEVEPK-DVDV----STRITPNVKLNIPILSAAMDTVTEWEMAVAMAREG 71 Query: 72 MFTAIHKHYSLDD 84 IH++ +++ Sbjct: 72 GLGVIHRNMGIEE 84 >4DQW-A nrPDB Length = 509 Score = 142 bits (359), Expect = 2e-34, Method: Compositional matrix adjust. Identities = 84/216 (38%), Positives = 124/216 (57%), Gaps = 10/216 (4%) Query: 132 NGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTK 191 +G+S+ +E V+ V+ FP+ ++ GN+ T E + L +GAD +KVG+GPGS+CTTR Sbjct: 270 HGHSKGVIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIV 329 Query: 192 TGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 GVG PQ+SA+ A + G +I+DGG GD+AKA AGA VM+G MF+G E Sbjct: 330 AGVGVPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEA 389 Query: 252 AGEVFERNGRKLKLFYGMSSDTAMN----------KHAGGVAEYRASEGKTVEVPYKGDV 301 GE+ GR K + GM S AM+ + A AE EG VPYKG + Sbjct: 390 PGEIELFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEGIEGRVPYKGAL 449 Query: 302 ENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 + ++GGLR+ Y G+A ++++ + F+R+T Sbjct: 450 SAIVHQLMGGLRAAMGYTGSADIQQMRTQPQFVRIT 485 Score = 35.4 bits (80), Expect = 0.032, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 6/84 (7%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI + L F DVLL P S + + +V L+ T + IP++ A MDTV Sbjct: 21 MLRISQE-ALTFDDVLLIPGYSEVLPK-DVSLKTRLT----RGIELNIPLVSAAMDTVTE 74 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDD 84 +A M+Q IHK+ ++ Sbjct: 75 ARLAIAMAQEGGIGIIHKNMGIEQ 98 >5UPU-A nrPDB Length = 407 Score = 140 bits (353), Expect = 8e-34, Method: Compositional matrix adjust. Identities = 108/356 (30%), Positives = 175/356 (49%), Gaps = 32/356 (8%) Query: 2 PRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTF 61 P A L L F DVLL P S + A D T K+ +P++ + MDTV Sbjct: 40 PHKVAMLGLTFDDVLLLPAASDVVP-ATADTSSQLT----KKIRLKVPLVSSAMDTVTES 94 Query: 62 EMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQN-----VAVSSGSGQNDLEKMTSI 116 MA M++ +H++ + + E ++ V + G G + + + Sbjct: 95 RMAIAMARAGGMGVLHRNLPVAEQ----AGQVEMVKRSGGLLVGAAVGVGGDAWVRAMML 150 Query: 117 LEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHT-IMAGNVVTGEMVEELILSGADI 175 ++A V + +D A+ ++ ++ V ++++ + ++ GNV T L+ +GAD Sbjct: 151 VDA--GVDVLVVDTAHAHNRLVLDMVGKLKSEVGDRVEVVGGNVATRSAAAALVDAGADA 208 Query: 176 IKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAG 235 +KVGVGPGS+CTTR GVG PQ++A++E + +I+DGG GD+AKA AG Sbjct: 209 VKVGVGPGSICTTRVVAGVGAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAG 268 Query: 236 ADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGV--------AEYRA 287 A MLG + +G E GE+ NG++ K + GM S AM G A+ Sbjct: 269 ASTAMLGSLLAGTAEAPGELIFVNGKQYKSYRGMGSLGAMRGRGGATSYSKDRYFADDAL 328 Query: 288 SEGKTV------EVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 SE K V VP++G + + I + GGLR+ Y G+ + E+ ++A F+R+T Sbjct: 329 SEDKLVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTI-EVLQQAQFVRIT 383 >4XTI-A nrPDB Length = 413 Score = 132 bits (333), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 101/349 (28%), Positives = 160/349 (45%), Gaps = 35/349 (10%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMS- 68 L + D L+ P + S E + R +K+ P + + MDTV +MA M+ Sbjct: 39 LTYNDFLVLPGKIDFPSS-----EVVLSSRLTKKITLNAPFVSSPMDTVTEADMAIHMAL 93 Query: 69 ---------------QHSMFTAIHKHYSLDDWKLFATNHPECLQNV-AVSSGSGQNDLEK 112 Q M + K+ + A+ + Q + + G+ D ++ Sbjct: 94 LGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGPLASKSADTKQLLCGAAIGTIDADRQR 153 Query: 113 MTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSG 172 + ++EA + + LD + G S + +K ++ FP+ ++AGNVVT E LI +G Sbjct: 154 LAMLVEA--GLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAG 211 Query: 173 ADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAF 232 AD +++G+G GS+C T+ G PQ +AV A+ I+DGG G + KA Sbjct: 212 ADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAI 271 Query: 233 GAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKH--AGGVAEYR---- 286 GA VM+GGM +G TE GE F R+G++LK + GM S AM K G A R Sbjct: 272 ALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGNAATSRYFSE 331 Query: 287 -----ASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRR 330 ++G T V KG ++ I + GL+ +C +G L E + Sbjct: 332 SDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREK 380 >4Z87-A nrPDB Length = 525 Score = 127 bits (318), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 80/238 (33%), Positives = 122/238 (51%), Gaps = 13/238 (5%) Query: 104 GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGE 163 G+ D +++ ++EA + + LD + G S + +K ++ FP+ ++AGNVVT E Sbjct: 257 GTIDADRQRLAMLVEA--GLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTRE 314 Query: 164 MVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCT 223 LI +GAD +++G+G GS+C T+ G PQ +AV A+ I+DGG Sbjct: 315 QAASLIHAGADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQ 374 Query: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKH--AGG 281 G + KA GA VM+GGM +G TE GE F R+G++LK + GM S AM K G Sbjct: 375 NIGHITKAIALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGN 434 Query: 282 VAEYR---------ASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRR 330 A R ++G T V KG ++ I + GL+ +C +G L E + Sbjct: 435 AATSRYFSESDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREK 492 >6I0M-A nrPDB Length = 517 Score = 124 bits (310), Expect = 9e-29, Method: Compositional matrix adjust. Identities = 75/269 (27%), Positives = 132/269 (49%), Gaps = 7/269 (2%) Query: 66 VMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKF 125 ++++ AI L + + + + + + G ++ +K L A V Sbjct: 214 IVNEDDELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDV 273 Query: 126 ICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSV 185 + LD + G S + +K ++ K+P ++ GNVVT + LI +G D ++VG+G GS+ Sbjct: 274 VVLDSSQGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSI 333 Query: 186 CTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMF 245 C T+ G PQ +AV + ++ A +I+DGG G +AKA GA VM+G + Sbjct: 334 CITQEVLACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLL 393 Query: 246 SGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEY-------RASEGKTVEVPYK 298 + TE GE F +G +LK + GM S AM+KH Y + ++G + V K Sbjct: 394 AATTEAPGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDK 453 Query: 299 GDVENTILDILGGLRSTCTYVGAAKLKEL 327 G + + ++ G++ +C +GA L ++ Sbjct: 454 GSIHKFVPYLIAGIQHSCQDIGAKSLTQV 482 >4AF0-B nrPDB Length = 556 Score = 122 bits (307), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 72/202 (35%), Positives = 113/202 (55%), Gaps = 3/202 (1%) Query: 88 FATNHPECLQ-NVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVR 146 +A+ PE Q + G+ D +++ + EA + + LD + G S + +EF+K ++ Sbjct: 260 YASKVPESKQLYCGAAIGTRPGDKDRLKLLAEA--GLDVVVLDSSQGNSVYQIEFIKWIK 317 Query: 147 AKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECA 206 +P+ ++AGNVVT E +LI +GAD +++G+G GS+C T+ VG PQ +AV A Sbjct: 318 QTYPKIDVIAGNVVTREQAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQGTAVYAVA 377 Query: 207 DSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLF 266 + A I+DGG G +AKA GA VM+GG+ +G TE GE F G+++K++ Sbjct: 378 EFASRFGIPCIADGGIGNIGHIAKALALGASAVMMGGLLAGTTESPGEYFYHEGKRVKVY 437 Query: 267 YGMSSDTAMNKHAGGVAEYRAS 288 GM S AM G A + S Sbjct: 438 RGMGSIEAMEHTQRGSASGKRS 459 >1JCN-A nrPDB Length = 514 Score = 118 bits (295), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 76/232 (32%), Positives = 119/232 (51%), Gaps = 11/232 (4%) Query: 104 GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGE 163 G+ ++D ++ + +A V I LD + G S + + V ++ K+P ++ GNVVT Sbjct: 251 GTREDDKYRLDLLTQA--GVDVIVLDSSQGNSVYQIAMVHYIKQKYPHLQVIGGNVVTAA 308 Query: 164 MVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCT 223 + LI +G D ++VG+G GS+C T+ G PQ +AV + A+ A II+DGG Sbjct: 309 QAKNLIDAGVDGLRVGMGCGSICITQEVMACGRPQGTAVYKVAEYARRFGVPIIADGGIQ 368 Query: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVA 283 G V KA GA VM+G + + TE GE F +G +LK + GM S AM K + Sbjct: 369 TVGHVVKALALGASTVMMGSLLAATTEAPGEYFFSDGVRLKKYRGMGSLDAMEKSSSSQK 428 Query: 284 EYRASEGKTVEVPY--------KGDVENTILDILGGLRSTCTYVGAAKLKEL 327 Y SEG V++ KG ++ + ++ G++ C +GA L L Sbjct: 429 RY-FSEGDKVKIAQGVSGSIQDKGSIQKFVPYLIAGIQHGCQDIGARSLSVL 479 >1AK5-A nrPDB Length = 503 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 82/280 (29%), Positives = 132/280 (47%), Gaps = 15/280 (5%) Query: 69 QHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDL-EKMTSILEAVPQVKFIC 127 QH + K Y D ++ + + V +G D E++ +++EA V +C Sbjct: 204 QHLRYIVFRKDY--DRSQVCHNELVDSQKRYLVGAGINTRDFRERVPALVEAGADV--LC 259 Query: 128 LDVANGYSEHFVEFVKLVRAKFPEHT-IMAGNVVTGEMVEELILSGADIIKVGVGPGSVC 186 +D ++G+SE + +R K+ + + AGN+V GE L +GAD IK+G+G GS+C Sbjct: 260 IDSSDGFSEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSIC 319 Query: 187 TTRTKTGVGYPQLSAVIECADSAH------GLKGHIISDGGCTCPGDVAKAFGAGADFVM 240 TR + G+G Q +AVI+ + G+ + SDGG + A GADF+M Sbjct: 320 ITREQKGIGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIM 379 Query: 241 LGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHA---GGVAEYRASEGKTVEVPY 297 LG F+ E NG +K ++G S A N GG + EG VPY Sbjct: 380 LGRYFARFEESPTRKVTINGSVMKEYWGEGSSRARNWQRYDLGGKQKLSFEEGVDSYVPY 439 Query: 298 KGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 G +++ + L ++ST GA + +L +A V+ Sbjct: 440 AGKLKDNVEASLNKVKSTMCNCGALTIPQLQSKAKITLVS 479 >1RI1-A nrPDB Length = 298 Score = 33.5 bits (75), Expect = 0.14, Method: Compositional matrix adjust. Identities = 15/38 (39%), Positives = 25/38 (65%), Gaps = 1/38 (2%) Query: 109 DLEKMTSI-LEAVPQVKFICLDVANGYSEHFVEFVKLV 145 +LEKM + +E+V + +F LD N E+FV+F ++V Sbjct: 197 ELEKMEDVPMESVREYRFTLLDSVNNCIEYFVDFTRMV 234 >1NF4-A nrPDB Length = 179 Score = 32.0 bits (71), Expect = 0.45, Method: Compositional matrix adjust. Identities = 28/119 (23%), Positives = 53/119 (44%), Gaps = 21/119 (17%) Query: 64 AAVMSQHSMFTAIHKHYSLDD---------WKLFATNHPECLQNVA--VSSGSGQNDLEK 112 A M H++ +++HYSLDD KL A + +N A + G+ +K Sbjct: 19 ARAMELHAIHQYMNQHYSLDDMDYGELAANMKLIAIDEMRHAENFAERIKELGGEPTTQK 78 Query: 113 MTSIL--EAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELI 169 ++ +AVP + D + E + +F+K+ + + G++VT + E +I Sbjct: 79 EGKVVTGQAVPVIYESDADQEDATIEAYSQFLKVCKEQ--------GDIVTARLFERII 129 >1TYG-A nrPDB Length = 253 Score = 28.1 bits (61), Expect = 5.2, Method: Compositional matrix adjust. Identities = 31/91 (34%), Positives = 38/91 (41%), Gaps = 15/91 (16%) Query: 158 NVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYP-QLSAVIECADSAHGLKGHI 216 +VV +EEL G I G P + G+ P LS +IE A K + Sbjct: 134 DVVLARKLEEL---GVHAIMPGASP-----IGSGQGILNPLNLSFIIEQA------KVPV 179 Query: 217 ISDGGCTCPGDVAKAFGAGADFVMLGGMFSG 247 I D G P D A A GAD V+L SG Sbjct: 180 IVDAGIGSPKDAAYAMELGADGVLLNTAVSG 210 >1J5S-A nrPDB Length = 463 Score = 28.1 bits (61), Expect = 6.2, Method: Compositional matrix adjust. Identities = 21/71 (29%), Positives = 30/71 (42%), Gaps = 2/71 (2%) Query: 245 FSGHTECAGEVFERNGRKLKLFYGMSSDTAM--NKHAGGVAEYRASEGKTVEVPYKGDVE 302 FSG E+ + + F M+ +T H G + +YR S KT+ GD+ Sbjct: 267 FSGEKLTQDEINDYKAFMMVQFGKMNQETNWVTQLHIGALRDYRDSLFKTLGPDSGGDIS 326 Query: 303 NTILDILGGLR 313 L I GLR Sbjct: 327 TNFLRIAEGLR 337 >3AK5-A nrPDB Length = 975 Score = 27.7 bits (60), Expect = 7.8, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 27/56 (48%), Gaps = 2/56 (3%) Query: 31 DLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLDDWK 86 D+ TFT N + T G P+I A +T + A HS+ T +S +DW+ Sbjct: 518 DISGTFTQENGRLTLQGHPVIHA-YNTQSVADKLAASGDHSVLTQ-PTSFSQEDWE 571 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2BWG-A nrPDB 474 e-134 2C6Q-A nrPDB 432 e-122 4MJM-A nrPDB 397 e-111 4FEZ-A nrPDB 396 e-111 5UQG-A nrPDB 394 e-110 1EEP-A nrPDB 383 e-107 1VRD-A nrPDB 375 e-104 4QJ1-A nrPDB 373 e-104 3FFS-A nrPDB 370 e-103 4XTI-A nrPDB 365 e-101 3R2G-A nrPDB 365 e-101 5AHL-A nrPDB 352 2e-97 3TSB-A nrPDB 345 2e-95 5UPU-A nrPDB 342 1e-94 4FXS-A nrPDB 340 4e-94 1YPF-A nrPDB 333 7e-92 1ZFJ-A nrPDB 329 1e-90 6I0M-A nrPDB 315 2e-86 4Z87-A nrPDB 309 1e-84 1JCN-A nrPDB 308 2e-84 4AF0-B nrPDB 294 5e-80 2CU0-A nrPDB 292 1e-79 4DQW-A nrPDB 290 5e-79 1AK5-A nrPDB 259 1e-69 Sequences not found previously or not previously below threshold: 6DVI-A nrPDB 52 3e-07 6BFG-A nrPDB 52 3e-07 2A85-A nrPDB 52 3e-07 5ZBN-A nrPDB 48 7e-06 4N6F-A nrPDB 44 7e-05 1AL8-A nrPDB 44 7e-05 2GJN-A nrPDB 43 2e-04 2CDH-0 nrPDB 42 3e-04 1P0K-A nrPDB 41 8e-04 2RDU-A nrPDB 41 0.001 3SGZ-A nrPDB 40 0.001 5ZKN-A nrPDB 40 0.001 2Z6J-A nrPDB 38 0.006 2J6X-A nrPDB 38 0.007 1TYG-A nrPDB 38 0.007 5GVH-A nrPDB 37 0.017 3BW4-A nrPDB 37 0.017 5LSM-A nrPDB 35 0.044 4JEJ-A nrPDB 35 0.047 4Q4K-A nrPDB 35 0.051 1VHC-A nrPDB 34 0.090 1YXY-A nrPDB 34 0.094 3SR7-A nrPDB 33 0.12 1MXS-A nrPDB 33 0.19 1N7K-A nrPDB 33 0.19 1H1Z-A nrPDB 32 0.32 1QAP-A nrPDB 32 0.36 2ZRW-A nrPDB 32 0.39 3F4W-A nrPDB 32 0.40 5Z9Y-A nrPDB 31 0.72 1SZG-A nrPDB 31 0.77 1EP3-A nrPDB 31 0.82 1QCW-A nrPDB 31 0.86 6CTY-A nrPDB 31 0.88 1WV2-A nrPDB 31 0.90 5UE9-A nrPDB 31 0.94 6NKE-A nrPDB 31 0.98 1YTE-A nrPDB 30 1.1 3O07-A nrPDB 30 1.2 2ZBT-A nrPDB 30 1.3 2A1T-A nrPDB 30 1.4 2ISS-A nrPDB 30 1.4 4WY0-A nrPDB 30 1.4 1EUA-A nrPDB 30 1.5 4MM1-A nrPDB 30 1.7 4NU7-A nrPDB 30 1.8 4XBS-A nrPDB 30 1.9 3OIX-A nrPDB 30 2.0 1XI3-A nrPDB 30 2.1 1KA9-F nrPDB 30 2.1 2NV2-A nrPDB 30 2.1 6HYE-A nrPDB 30 2.2 4UTT-A nrPDB 29 2.4 3BIC-A nrPDB 29 2.4 2P8U-A nrPDB 29 2.5 4HDR-A nrPDB 29 2.6 4IQL-A nrPDB 29 2.6 2HTM-A nrPDB 29 3.1 4ADT-A nrPDB 29 3.7 3W7D-A nrPDB 29 3.8 4X2R-A nrPDB 28 4.1 1Y0E-A nrPDB 28 4.1 5UMF-A nrPDB 28 4.4 3MDE-A nrPDB 28 5.0 2GGG-A nrPDB 28 5.4 1H5Y-A nrPDB 28 5.7 1JUE-A nrPDB 28 6.1 5EY5-A nrPDB 28 6.7 6DU6-A nrPDB 28 6.9 4AXK-A nrPDB 28 6.9 5G1T-A nrPDB 28 7.4 3OA3-A nrPDB 28 7.4 4EVZ-A nrPDB 28 8.5 1OFP-A nrPDB 27 8.7 3L9X-A nrPDB 27 8.8 4N02-A nrPDB 27 9.1 5LNS-A nrPDB 27 9.3 2W6R-A nrPDB 27 9.3 4B2O-A nrPDB 27 9.4 2YZR-A nrPDB 27 9.5 3TI8-A nrPDB 27 9.6 >2BWG-A nrPDB Length = 367 Score = 474 bits (1220), Expect = e-134, Method: Composition-based stats. Identities = 344/345 (99%), Positives = 344/345 (99%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT Sbjct: 23 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 82 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 120 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV Sbjct: 83 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 142 Query: 121 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 180 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV Sbjct: 143 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 202 Query: 181 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 240 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM Sbjct: 203 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 262 Query: 241 LGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD 300 LGGMFSGHTECAGEV ERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD Sbjct: 263 LGGMFSGHTECAGEVIERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGD 322 Query: 301 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 345 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS Sbjct: 323 VENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 367 >2C6Q-A nrPDB Length = 351 Score = 432 bits (1112), Expect = e-122, Method: Composition-based stats. Identities = 267/333 (80%), Positives = 304/333 (91%) Query: 9 KLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMS 68 LDFKDVLLRPKRS+LKSR+EVDL R+F+FRNSKQTYSG+PII ANMDTVGTFEMA V+ Sbjct: 19 SLDFKDVLLRPKRSTLKSRSEVDLTRSFSFRNSKQTYSGVPIIAANMDTVGTFEMAKVLC 78 Query: 69 QHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICL 128 + S+FTA+HKHYSL W+ FA +P+CL+++A SSG+G +D E++ ILEA+PQVK+ICL Sbjct: 79 KFSLFTAVHKHYSLVQWQEFAGQNPDCLEHLAASSGTGSSDFEQLEQILEAIPQVKYICL 138 Query: 129 DVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTT 188 DVANGYSEHFVEFVK VR +FP+HTIMAGNVVTGEMVEELILSGADIIKVG+GPGSVCTT Sbjct: 139 DVANGYSEHFVEFVKDVRKRFPQHTIMAGNVVTGEMVEELILSGADIIKVGIGPGSVCTT 198 Query: 189 RTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGH 248 R KTGVGYPQLSAV+ECAD+AHGLKGHIISDGGC+CPGDVAKAFGAGADFVMLGGM +GH Sbjct: 199 RKKTGVGYPQLSAVMECADAAHGLKGHIISDGGCSCPGDVAKAFGAGADFVMLGGMLAGH 258 Query: 249 TECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILDI 308 +E GE+ ER+G+K KLFYGMSS+ AM K+AGGVAEYRASEGKTVEVP+KGDVE+TI DI Sbjct: 259 SESGGELIERDGKKYKLFYGMSSEMAMKKYAGGVAEYRASEGKTVEVPFKGDVEHTIRDI 318 Query: 309 LGGLRSTCTYVGAAKLKELSRRATFIRVTQQHN 341 LGG+RSTCTYVGAAKLKELSRR TFIRVTQQ N Sbjct: 319 LGGIRSTCTYVGAAKLKELSRRTTFIRVTQQVN 351 >4MJM-A nrPDB Length = 385 Score = 397 bits (1021), Expect = e-111, Method: Composition-based stats. Identities = 127/359 (35%), Positives = 185/359 (51%), Gaps = 35/359 (9%) Query: 7 DLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAV 66 L F DVLL P +S + R EV ++ + + IP+I A MDTV +MA Sbjct: 11 KEGLTFDDVLLVPAKSDVLPR-EVSVKTVLS----ESLQLNIPLISAGMDTVTEADMAIA 65 Query: 67 MSQHSMFTAIHKHYSLDDWK-----------------------LFATNHPECLQNVAVSS 103 M++ IHK+ S++ + + V + Sbjct: 66 MARQGGLGIIHKNMSIEQQAEQVDKVKRSESGGIKDIEKVIEFPNSAKDKQGRLLVGAAV 125 Query: 104 GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGE 163 G + + ++ ++++A V I LD A+G+S+ ++ VK VRAK+P I+AGNV T E Sbjct: 126 GVTADAMTRIDALVKA--SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAE 183 Query: 164 MVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCT 223 + LI +GA+++KVG+GPGS+CTTR GVG PQL+AV +CA A +I+DGG Sbjct: 184 ATKALIEAGANVVKVGIGPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIK 243 Query: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGG-- 281 GD+ KA AGA VMLG MF+G E GE GR+ K++ GM S AM K + Sbjct: 244 YSGDMVKALAAGAHVVMLGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKGSKDRY 303 Query: 282 ---VAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 + EG VPYKG + +T+ ++GGLR+ Y GA L+ L A FIR++ Sbjct: 304 FQEGNKKLVPEGIEGRVPYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQFIRMS 362 >4FEZ-A nrPDB Length = 388 Score = 396 bits (1017), Expect = e-111, Method: Composition-based stats. Identities = 119/367 (32%), Positives = 181/367 (49%), Gaps = 38/367 (10%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI A L F DVLL P S++ R +K IP++ A+MDTV Sbjct: 6 MLRI-AKEALTFDDVLLVPAHSTVLPN-----TADLRTRLTKNIALNIPMVSASMDTVTE 59 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDW-----------------------KLFATNHPECLQ 97 +A ++Q IHK+ S++ K A + Sbjct: 60 ARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVKIFESGGAKDFHKAESKPNACKDEQGRL 119 Query: 98 NVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAG 157 V + G+ + E++ +++EA V + +D ++G+SE ++ ++ RA +P I+ G Sbjct: 120 RVGAAVGAAPGNEERVKALVEA--GVDVLLIDSSHGHSEGVLQRIRETRAAYPHLEIIGG 177 Query: 158 NVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHII 217 NV T E LI +G +KVG+GPGS+CTTR TGVG PQ++A+ + A A+ +I Sbjct: 178 NVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVPQITAIADAAGVANEYGIPVI 237 Query: 218 SDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNK 277 +DGG GD++KA AGA VM+G MF+G E GEV GR K + GM S AM+K Sbjct: 238 ADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVILYQGRSYKAYRGMGSLGAMSK 297 Query: 278 -------HAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRR 330 A+ EG + YKG ++ I +GGLRS G+A +++L + Sbjct: 298 GSSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEIIHQQMGGLRSCMGLTGSATVEDLRTK 357 Query: 331 ATFIRVT 337 A F+R++ Sbjct: 358 AQFVRIS 364 >5UQG-A nrPDB Length = 406 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 118/362 (32%), Positives = 184/362 (50%), Gaps = 35/362 (9%) Query: 4 IDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEM 63 L F+DVLLRP S + + EV + T K +P+I A MDTV Sbjct: 26 KIVKRALTFEDVLLRPGYSEVLPK-EVKIHTKLT----KNITLNMPLISAAMDTVTEHRA 80 Query: 64 AAVMSQHSMFTAIHKHYSL---------------------DDWKLFATNHPECLQNVAVS 102 A +M++ IHK+ + K + + + + V Sbjct: 81 AIMMARLGGLGVIHKNMDIASQVREVKRVKKSESGGIKDLKKRKEYPDANKDNFGRLRVG 140 Query: 103 SGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTG 162 + G ++++ +++EA V + LD A+G+S+ ++ VK ++AK+P ++AGN+ T Sbjct: 141 AAIGVGQMDRVDALVEA--GVDVVVLDSAHGHSKGIIDTVKAIKAKYPNLDLIAGNIATA 198 Query: 163 EMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGC 222 + L +G D +KVG+GPGS+CTTR +GVG PQ+SA+ EC + A+ +I+DGG Sbjct: 199 AAAKALCEAGVDAVKVGIGPGSICTTRIVSGVGVPQISAIDECVEEANKFGVPVIADGGI 258 Query: 223 TCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNK----- 277 GD+AKA GA VM+G + +G E GE+F GR+ K + GM S AM K Sbjct: 259 KYSGDIAKALAVGASSVMIGSLLAGTDESPGELFTYQGRQYKSYRGMGSLGAMQKGSSDR 318 Query: 278 --HAGGVAEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIR 335 G + EG VPY G + + + +LGGLRS+ YVGA +++ +RA F+ Sbjct: 319 YFQQGTAQDKLVPEGIEGRVPYVGSIRSVVHQLLGGLRSSMGYVGAKDIEDFQKRAEFVE 378 Query: 336 VT 337 +T Sbjct: 379 IT 380 >1EEP-A nrPDB Length = 404 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 114/396 (28%), Positives = 183/396 (46%), Gaps = 65/396 (16%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 MP L F DV L P++SS+ +EV L+ T K IP + + MDTV Sbjct: 1 MPNKITKEALTFDDVSLIPRKSSVLP-SEVSLKTQLT----KNISLNIPFLSSAMDTVTE 55 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWK---------------------------------- 86 +MA +++ IHK+ S++ + Sbjct: 56 SQMAIAIAKEGGIGIIHKNMSIEAQRKEIEKVKTYKFQKTINTNGDTNEQKPEIFTAKQH 115 Query: 87 ----------------LFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDV 130 A V + + +E++ +++A V + +D Sbjct: 116 LEKSDAYKNAEHKEDFPNACKDLNNKLRVGAAVSIDIDTIERVEELVKAH--VDILVIDS 173 Query: 131 ANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRT 190 A+G+S +E +K ++ K+P ++AGN+VT E +LI GAD +KVG+GPGS+CTTR Sbjct: 174 AHGHSTRIIELIKKIKTKYPNLDLIAGNIVTKEAALDLISVGADCLKVGIGPGSICTTRI 233 Query: 191 KTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTE 250 GVG PQ++A+ + ++ + II+DGG GDV KA AGAD VM+G +F+G E Sbjct: 234 VAGVGVPQITAICDVYEACNNTNICIIADGGIRFSGDVVKAIAAGADSVMIGNLFAGTKE 293 Query: 251 CAGEVFERNGRKLKLFYGMSSDTAMNKHA--------GGVAEYRASEGKTVEVPYKGDVE 302 E NG+K K + GM S +AM + + + EG VPY G ++ Sbjct: 294 SPSEEIIYNGKKFKSYVGMGSISAMKRGSKSRYFQLENNEPKKLVPEGIEGMVPYSGKLK 353 Query: 303 NTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQ 338 + + + GGL S Y+GAA + +L + F++++ Sbjct: 354 DILTQLKGGLMSGMGYLGAATISDLKINSKFVKISH 389 >1VRD-A nrPDB Length = 494 Score = 375 bits (962), Expect = e-104, Method: Composition-based stats. Identities = 113/340 (33%), Positives = 178/340 (52%), Gaps = 23/340 (6%) Query: 3 RIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFE 62 R + +L KD L+ P+ + + ++ LE+ + + +P++ + VG Sbjct: 148 RFEKNLSKKIKD-LMTPREKLIVAPPDISLEKAKEILH-QHRIEKLPLVSKDNKLVGLIT 205 Query: 63 MAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQ 122 + +MS A + V + G+ +E++ +++A Sbjct: 206 IKDIMSVIE--------------HPNAARDEKGRLLVGAAVGTSPETMERVEKLVKA--G 249 Query: 123 VKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGP 182 V I +D A+G+S +E +++++A +P+ ++AGNV T E E LI +GAD +KVGVGP Sbjct: 250 VDVIVIDTAHGHSRRVIETLEMIKADYPDLPVVAGNVATPEGTEALIKAGADAVKVGVGP 309 Query: 183 GSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLG 242 GS+CTTR GVG PQL+AV+EC++ A II+DGG GD+ KA AGA+ VM+G Sbjct: 310 GSICTTRVVAGVGVPQLTAVMECSEVARKYDVPIIADGGIRYSGDIVKALAAGAESVMVG 369 Query: 243 GMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGG-----VAEYRASEGKTVEVPY 297 +F+G E GE GRK K + GM S AM + EG VPY Sbjct: 370 SIFAGTEEAPGETILYQGRKYKAYRGMGSLGAMRSGSADRYGQEGENKFVPEGIEGMVPY 429 Query: 298 KGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 KG V++ + ++GGLRS Y+GA +KEL +A F+++T Sbjct: 430 KGTVKDVVHQLVGGLRSGMGYIGARTIKELQEKAVFVKIT 469 Score = 77.8 bits (190), Expect = 6e-15, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 5/79 (6%) Query: 7 DLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAV 66 L F DVLL P+ S + + + R ++Q IP++ A MDTV +A Sbjct: 14 KEALTFDDVLLVPQYSEVLPK-----DVKIDTRLTRQIRINIPLVSAAMDTVTEAALAKA 68 Query: 67 MSQHSMFTAIHKHYSLDDW 85 +++ IHK+ + D+ Sbjct: 69 LAREGGIGIIHKNLTPDEQ 87 >4QJ1-A nrPDB Length = 361 Score = 373 bits (958), Expect = e-104, Method: Composition-based stats. Identities = 118/344 (34%), Positives = 178/344 (51%), Gaps = 16/344 (4%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M + L F+D+LL P S + R EV LE T K IP+I + MDTV Sbjct: 4 MGTKNIGKGLTFEDILLVPNYSEVLPR-EVSLETKLT----KNVSLKIPLISSAMDTVTE 58 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 120 MA M++ IHK+ ++ + V + G N++E+ ++EA Sbjct: 59 HLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNSGG-LRVGAAIGVNEIERAKLLVEA- 116 Query: 121 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 180 V I LD A+G+S + + +K +++K ++ GNVVT E +ELI +GAD IKVG+ Sbjct: 117 -GVDVIVLDSAHGHSLNIIRTLKEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGI 174 Query: 181 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 240 GPGS+CTTR GVG PQ++A+ +C+ A II+DGG GD+ KA GA VM Sbjct: 175 GPGSICTTRIVAGVGVPQITAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVM 234 Query: 241 LGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGV-------AEYRASEGKTV 293 +G + +G E GE K + GM S AM +G EG Sbjct: 235 IGSILAGTEESPGEKELIGDTVYKYYRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEG 294 Query: 294 EVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 V YKG++E + ++GGLRS Y+G+A ++EL ++++++ +T Sbjct: 295 RVKYKGEMEGVVYQLVGGLRSCMGYLGSASIEELWKKSSYVEIT 338 >3FFS-A nrPDB Length = 400 Score = 370 bits (950), Expect = e-103, Method: Composition-based stats. Identities = 118/385 (30%), Positives = 182/385 (47%), Gaps = 56/385 (14%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M + L F+D+LL P S + R EV LE T K IP+I + MDTV Sbjct: 1 MGTKNIGKGLTFEDILLVPNYSEVLPR-EVSLETKLT----KNVSLKIPLISSAMDTVTE 55 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWK---------------------------------- 86 MA M++ IHK+ ++ Sbjct: 56 HLMAVGMARLGGIGIIHKNMDMESQVNEVLKVKNWISNLEKNESTPDQNLDKESTDGKDT 115 Query: 87 -------LFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFV 139 ++ + + + V + G N++E+ ++EA V I LD A+G+S + + Sbjct: 116 KSNNNIDAYSNENLDNKGRLRVGAAIGVNEIERAKLLVEA--GVDVIVLDSAHGHSLNII 173 Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQL 199 +K +++K ++ GNVVT E +ELI +GAD IKVG+GPGS+CTTR GVG PQ+ Sbjct: 174 RTLKEIKSKM-NIDVIVGNVVTEEATKELIENGADGIKVGIGPGSICTTRIVAGVGVPQI 232 Query: 200 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERN 259 +A+ +C+ A II+DGG GD+ KA GA VM+G + +G E GE Sbjct: 233 TAIEKCSSVASKFGIPIIADGGIRYSGDIGKALAVGASSVMIGSILAGTEESPGEKELIG 292 Query: 260 GRKLKLFYGMSSDTAMNKHAGGV-------AEYRASEGKTVEVPYKGDVENTILDILGGL 312 K + GM S AM +G EG V YKG++E + ++GGL Sbjct: 293 DTVYKYYRGMGSVGAMKSGSGDRYFQEKRPENKMVPEGIEGRVKYKGEMEGVVYQLVGGL 352 Query: 313 RSTCTYVGAAKLKELSRRATFIRVT 337 RS Y+G+A ++EL ++++++ +T Sbjct: 353 RSCMGYLGSASIEELWKKSSYVEIT 377 >4XTI-A nrPDB Length = 413 Score = 365 bits (938), Expect = e-101, Method: Composition-based stats. Identities = 101/352 (28%), Positives = 159/352 (45%), Gaps = 35/352 (9%) Query: 9 KLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMS 68 L + D L+ P + S E + R +K+ P + + MDTV +MA M+ Sbjct: 38 GLTYNDFLVLPGKIDFPSS-----EVVLSSRLTKKITLNAPFVSSPMDTVTEADMAIHMA 92 Query: 69 QHSMFTAIH----------------KHYSLDDWKLFATNHPECLQNV-AVSSGSGQNDLE 111 IH K+ + A+ + Q + + G+ D + Sbjct: 93 LLGGIGIIHHNCTAEEQAEMVRRVKKYENGSQDGPLASKSADTKQLLCGAAIGTIDADRQ 152 Query: 112 KMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILS 171 ++ ++EA + + LD + G S + +K ++ FP+ ++AGNVVT E LI + Sbjct: 153 RLAMLVEA--GLDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHA 210 Query: 172 GADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKA 231 GAD +++G+G GS+C T+ G PQ +AV A+ I+DGG G + KA Sbjct: 211 GADGLRIGMGSGSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKA 270 Query: 232 FGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKH--AGGVAEYR--- 286 GA VM+GGM +G TE GE F R+G++LK + GM S AM K G A R Sbjct: 271 IALGASTVMMGGMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGNAATSRYFS 330 Query: 287 ------ASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRAT 332 ++G T V KG ++ I + GL+ +C +G L E + Sbjct: 331 ESDKVLVAQGVTGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREKVD 382 >3R2G-A nrPDB Length = 361 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 126/336 (37%), Positives = 187/336 (55%), Gaps = 13/336 (3%) Query: 4 IDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEM 63 + D + F DVLL P + +SR V E T T R K +P+I ANMDT+ M Sbjct: 2 VMTDQAITFDDVLLVPSYNHHESRRVV--ETTSTDRLGK-LTLNLPVISANMDTITESNM 58 Query: 64 AAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQV 123 A M A+H+ ++++ +C V VS G +N+L++ ++ +A Sbjct: 59 ANFMHSKGAMGALHRFMTIEEN---IQEFKKCKGPVFVSVGCTENELQRAEALRDA--GA 113 Query: 124 KFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPG 183 F C+DVA+ ++++ + +K +R IMAGNV T + L GADIIK G+G G Sbjct: 114 DFFCVDVAHAHAKYVGKTLKSLRQLLGSRCIMAGNVATYAGADYLASCGADIIKAGIGGG 173 Query: 184 SVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 SVC+TR KTG G P L+ + +C+ + I++DGG GD+ KA GADFVM+GG Sbjct: 174 SVCSTRIKTGFGVPMLTCIQDCSRADR----SIVADGGIKTSGDIVKALAFGADFVMIGG 229 Query: 244 MFSGHTECAGEVFER-NGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVE 302 M +G GEVF++ +G K+K + GM+S A G + E++ +EG EVP+K + + Sbjct: 230 MLAGSAPTPGEVFQKDDGSKVKRYRGMASREAQEAFLGQMHEWKTAEGVATEVPFKENPD 289 Query: 303 NTILDILGGLRSTCTYVGAAKLKELSRRATFIRVTQ 338 I DI+GGLRS TY GA + EL R+ ++ VTQ Sbjct: 290 GIIADIIGGLRSGLTYAGADSISELQRKLNYVIVTQ 325 >5AHL-A nrPDB Length = 400 Score = 352 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 119/364 (32%), Positives = 182/364 (50%), Gaps = 35/364 (9%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI L F DVLL P S + + +V L+ R ++ IP++ A MDTV Sbjct: 21 MLRISQ-EALTFDDVLLIPGYSEVLPK-DVSLKT----RLTRGIELNIPLVSAAMDTVTE 74 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWK-----------------LFATNHPECLQNVAVSS 103 +A M+Q IHK+ ++ A+ + V + Sbjct: 75 ARLAIAMAQEGGIGIIHKNMGIEQQAAEVRKVKKHETAKAKTYPLASKDEQGRLRVGAAV 134 Query: 104 GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGE 163 G+G + E++ +++ A V + A+G+S+ +E V+ V+ FP+ ++ GN+ T E Sbjct: 135 GTGADTGERVAALVAAGVDVVVVD--TAHGHSKGVIERVRWVKQTFPDVQVIGGNIATAE 192 Query: 164 MVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCT 223 + L +GAD +KVG+GPGS+CTTR GVG PQ+SA+ A + G +I+DGG Sbjct: 193 AAKALAEAGADAVKVGIGPGSICTTRIVAGVGVPQISAIANVAAALEGTGVPLIADGGIR 252 Query: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGV- 282 GD+AKA AGA VM+G MF+G E GE+ GR K + GM S AM+ G Sbjct: 253 FSGDLAKAMVAGAYCVMMGSMFAGTEEAPGEIELFQGRSYKSYRGMGSLGAMSGSQGSSD 312 Query: 283 ---------AEYRASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATF 333 AE EG VPYKG + + ++GGLR+ Y G+A ++++ + F Sbjct: 313 RYFQDASAGAEKLVPEGIEGRVPYKGALSAIVHQLMGGLRAAMGYTGSADIQQMRTQPQF 372 Query: 334 IRVT 337 +R+T Sbjct: 373 VRIT 376 >3TSB-A nrPDB Length = 511 Score = 345 bits (885), Expect = 2e-95, Method: Composition-based stats. Identities = 111/342 (32%), Positives = 166/342 (48%), Gaps = 28/342 (8%) Query: 3 RIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFE 62 R D + DV+ + L + K +P++ N G Sbjct: 168 RFIQDYSIKISDVM---TKEQLITAPVGTTLSEAEKILQKYKIEKLPLVDNNGVLQGLIT 224 Query: 63 MAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQN--VAVSSGSGQNDLEKMTSILEAV 120 + + + F + + V + G + + ++ ++++A Sbjct: 225 IKDI----------------EKVIEFPNSAKDKQGRLLVGAAVGVTADAMTRIDALVKA- 267 Query: 121 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGV 180 V I LD A+G+S+ ++ VK VRAK+P I+AGNV T E + LI +GA+++KVG+ Sbjct: 268 -SVDAIVLDTAHGHSQGVIDKVKEVRAKYPSLNIIAGNVATAEATKALIEAGANVVKVGI 326 Query: 181 GPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 240 GPGS+CTTR GVG PQL+AV +CA A +I+DGG GD+ KA AGA VM Sbjct: 327 GPGSICTTRVVAGVGVPQLTAVYDCATEARKHGIPVIADGGIKYSGDMVKALAAGAHVVM 386 Query: 241 LGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGG-----VAEYRASEGKTVEV 295 LG MF+G E GE GR+ K++ GM S AM K + + EG V Sbjct: 387 LGSMFAGVAESPGETEIYQGRQFKVYRGMGSVGAMEKGSKDRYFQEGNKKLVPEGIEGRV 446 Query: 296 PYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 PYKG + +T+ ++GGLR+ Y GA L+ L A FIR++ Sbjct: 447 PYKGPLADTVHQLVGGLRAGMGYCGAQDLEFLRENAQFIRMS 488 Score = 87.0 bits (214), Expect = 1e-17, Method: Composition-based stats. Identities = 26/89 (29%), Positives = 39/89 (43%), Gaps = 5/89 (5%) Query: 7 DLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAV 66 L F DVLL P +S + R EV ++ + + IP+I A MDTV +MA Sbjct: 32 KEGLTFDDVLLVPAKSDVLPR-EVSVKTVLS----ESLQLNIPLISAGMDTVTEADMAIA 86 Query: 67 MSQHSMFTAIHKHYSLDDWKLFATNHPEC 95 M++ IHK+ S++ Sbjct: 87 MARQGGLGIIHKNMSIEQQAEQVDKVKRS 115 >5UPU-A nrPDB Length = 407 Score = 342 bits (877), Expect = 1e-94, Method: Composition-based stats. Identities = 104/352 (29%), Positives = 169/352 (48%), Gaps = 24/352 (6%) Query: 2 PRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTF 61 P A L L F DVLL P S + A D T K+ +P++ + MDTV Sbjct: 40 PHKVAMLGLTFDDVLLLPAASDVVP-ATADTSSQLT----KKIRLKVPLVSSAMDTVTES 94 Query: 62 EMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQN-VAVSSGSGQNDLEKMTSILEAV 120 MA M++ +H++ + + V + G G + + +++A Sbjct: 95 RMAIAMARAGGMGVLHRNLPVAEQAGQVEMVKRSGGLLVGAAVGVGGDAWVRAMMLVDA- 153 Query: 121 PQVKFICLDVANGYSEHFVEFVKLVRAKFPEH-TIMAGNVVTGEMVEELILSGADIIKVG 179 V + +D A+ ++ ++ V ++++ + ++ GNV T L+ +GAD +KVG Sbjct: 154 -GVDVLVVDTAHAHNRLVLDMVGKLKSEVGDRVEVVGGNVATRSAAAALVDAGADAVKVG 212 Query: 180 VGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFV 239 VGPGS+CTTR GVG PQ++A++E + +I+DGG GD+AKA AGA Sbjct: 213 VGPGSICTTRVVAGVGAPQITAILEAVAACRPAGVPVIADGGLQYSGDIAKALAAGASTA 272 Query: 240 MLGGMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVA--------------EY 285 MLG + +G E GE+ NG++ K + GM S AM G + + Sbjct: 273 MLGSLLAGTAEAPGELIFVNGKQYKSYRGMGSLGAMRGRGGATSYSKDRYFADDALSEDK 332 Query: 286 RASEGKTVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 EG VP++G + + I + GGLR+ Y G+ ++ L +A F+R+T Sbjct: 333 LVPEGIEGRVPFRGPLSSVIHQLTGGLRAAMGYTGSPTIEVLQ-QAQFVRIT 383 >4FXS-A nrPDB Length = 496 Score = 340 bits (873), Expect = 4e-94, Method: Composition-based stats. Identities = 93/267 (34%), Positives = 145/267 (54%), Gaps = 9/267 (3%) Query: 78 KHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEH 137 K + + K A + V + G+ + E++ +++EA V + +D ++G+SE Sbjct: 201 KDFHKAESKPNACKDEQGRLRVGAAVGAAPGNEERVKALVEA--GVDVLLIDSSHGHSEG 258 Query: 138 FVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYP 197 ++ ++ RA +P I+ GNV T E LI +G +KVG+GPGS+CTTR TGVG P Sbjct: 259 VLQRIRETRAAYPHLEIIGGNVATAEGARALIEAGVSAVKVGIGPGSICTTRIVTGVGVP 318 Query: 198 QLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFE 257 Q++A+ + A A+ +I+DGG GD++KA AGA VM+G MF+G E GEV Sbjct: 319 QITAIADAAGVANEYGIPVIADGGIRFSGDISKAIAAGASCVMVGSMFAGTEEAPGEVIL 378 Query: 258 RNGRKLKLFYGMSSDTAMNK-------HAGGVAEYRASEGKTVEVPYKGDVENTILDILG 310 GR K + GM S AM+K A+ EG + YKG ++ I +G Sbjct: 379 YQGRSYKAYRGMGSLGAMSKGSSDRYFQTDNAADKLVPEGIEGRIAYKGHLKEIIHQQMG 438 Query: 311 GLRSTCTYVGAAKLKELSRRATFIRVT 337 GLRS G+A +++L +A F+R++ Sbjct: 439 GLRSCMGLTGSATVEDLRTKAQFVRIS 465 Score = 83.6 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 6/93 (6%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI A L F DVLL P S++ R +K IP++ A+MDTV Sbjct: 3 MLRI-AKEALTFDDVLLVPAHSTVLPN-----TADLRTRLTKNIALNIPMVSASMDTVTE 56 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHP 93 +A ++Q IHK+ S++ Sbjct: 57 ARLAIALAQEGGIGFIHKNMSIEQQAAQVHQVK 89 >1YPF-A nrPDB Length = 336 Score = 333 bits (854), Expect = 7e-92, Method: Composition-based stats. Identities = 104/338 (30%), Positives = 181/338 (53%), Gaps = 22/338 (6%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 D++D+ L P + + SR+E D T K +P++ ANM T+ +A +++ Sbjct: 14 FDYEDIQLIPAKCIVNSRSECDTTVTLGKHKFK-----LPVVPANMQTIIDERIATYLAE 68 Query: 70 HSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLD 129 ++ F +H+ + + F + ++S G +++ E + + ++I +D Sbjct: 69 NNYFYIMHR-FQPEKRISFIRDMQSRGLIASISVGVKEDEYEFVQQLAAEHLTPEYITID 127 Query: 130 VANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTR 189 +A+G+S + ++ ++ PE ++AGNV T E V EL +GAD KVG+GPG VC T+ Sbjct: 128 IAHGHSNAVINMIQHIKKHLPESFVIAGNVGTPEAVRELENAGADATKVGIGPGKVCITK 187 Query: 190 TKTGVGY--PQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSG 247 KTG G QL+A+ CA +A II+DGG GDVAK+ GA VM+G +F+G Sbjct: 188 IKTGFGTGGWQLAALRWCAKAASK---PIIADGGIRTNGDVAKSIRFGATMVMIGSLFAG 244 Query: 248 HTECAGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEYRASEGKTVEVPYKGDVENTILD 307 H E GE E++G+ K ++G +S+ E + EGK + V +KG +E+T+++ Sbjct: 245 HEESPGETIEKDGKLYKEYFGSASEFQ-------KGEKKNVEGKKMFVEHKGSLEDTLIE 297 Query: 308 ILGGLRSTCTYVGAAKLKELSRRATFIRVTQQHNTVFS 345 + L+S+ +Y G KL + ++ V N++F+ Sbjct: 298 MEQDLQSSISYAGGTKLDSIRT-VDYVVVK---NSIFN 331 >1ZFJ-A nrPDB Length = 491 Score = 329 bits (843), Expect = 1e-90, Method: Composition-based stats. Identities = 101/326 (30%), Positives = 148/326 (45%), Gaps = 25/326 (7%) Query: 20 KRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKH 79 + + DLE + + +P++ + G + K Sbjct: 160 SEHLVTAAVGTDLETAERILH-EHRIEKLPLVDNSGRLSGLITI--------------KD 204 Query: 80 YSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFV 139 A VA + G + E+ ++ EA I +D A+G+S + Sbjct: 205 IEKVIEFPHAAKDEFGRLLVAAAVGVTSDTFERAEALFEA--GADAIVIDTAHGHSAGVL 262 Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQL 199 + +RA FP T++AGN+ T E L +G D++KVG+GPGS+CTTR GVG PQ+ Sbjct: 263 RKIAEIRAHFPNRTLIAGNIATAEGARALYDAGVDVVKVGIGPGSICTTRVVAGVGVPQV 322 Query: 200 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERN 259 +A+ + A A II+DGG GD+ KA AG + VMLG MF+G E GE Sbjct: 323 TAIYDAAAVAREYGKTIIADGGIKYSGDIVKALAAGGNAVMLGSMFAGTDEAPGETEIYQ 382 Query: 260 GRKLKLFYGMSSDTAMNKHAG--------GVAEYRASEGKTVEVPYKGDVENTILDILGG 311 GRK K + GM S AM K + A EG V YKG + + +LGG Sbjct: 383 GRKYKTYRGMGSIAAMKKGSSDRYFQGSVNEANKLVPEGIEGRVAYKGAASDIVFQMLGG 442 Query: 312 LRSTCTYVGAAKLKELSRRATFIRVT 337 +RS YVGA ++EL A F+ ++ Sbjct: 443 IRSGMGYVGAGDIQELHENAQFVEMS 468 Score = 75.5 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 36/93 (38%), Gaps = 5/93 (5%) Query: 7 DLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAV 66 F DVLL P S + EVDL+ IPII A MDTV +MA Sbjct: 9 KKGYTFDDVLLIPAESHVLP-NEVDLKTKLAD----NLTLNIPIITAAMDTVTGSKMAIA 63 Query: 67 MSQHSMFTAIHKHYSLDDWKLFATNHPECLQNV 99 +++ IHK+ S+ + V Sbjct: 64 IARAGGLGVIHKNMSITEQAEEVRKVKRSENGV 96 >6I0M-A nrPDB Length = 517 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 80/324 (24%), Positives = 146/324 (45%), Gaps = 24/324 (7%) Query: 12 FKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHS 71 F + ++ + + + A + L+ + +PI+ ++ Sbjct: 177 FLEEIMTKREDLVVAPAGITLKEANEILQ-RSKKGKLPIV----------------NEDD 219 Query: 72 MFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVA 131 AI L + + + + + + G ++ +K L A V + LD + Sbjct: 220 ELVAIIARTDLKKNRDYPLASKDAKKQLLCGAAIGTHEDDKYRLDLLAQAGVDVVVLDSS 279 Query: 132 NGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTK 191 G S + +K ++ K+P ++ GNVVT + LI +G D ++VG+G GS+C T+ Sbjct: 280 QGNSIFQINMIKYIKDKYPNLQVIGGNVVTAAQAKNLIDAGVDALRVGMGSGSICITQEV 339 Query: 192 TGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 G PQ +AV + ++ A +I+DGG G +AKA GA VM+G + + TE Sbjct: 340 LACGRPQATAVYKVSEYARRFGVPVIADGGIQNVGHIAKALALGASTVMMGSLLAATTEA 399 Query: 252 AGEVFERNGRKLKLFYGMSSDTAMNKHAGGVAEY-------RASEGKTVEVPYKGDVENT 304 GE F +G +LK + GM S AM+KH Y + ++G + V KG + Sbjct: 400 PGEYFFSDGIRLKKYRGMGSLDAMDKHLSSQNRYFSEADKIKVAQGVSGAVQDKGSIHKF 459 Query: 305 ILDILGGLRSTCTYVGAAKLKELS 328 + ++ G++ +C +GA L ++ Sbjct: 460 VPYLIAGIQHSCQDIGAKSLTQVR 483 Score = 65.9 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 22/113 (19%), Positives = 42/113 (37%), Gaps = 6/113 (5%) Query: 9 KLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMS 68 L + D L+ P + +VDL T K+ P++ + MDTV MA M+ Sbjct: 32 GLTYNDFLILPGYIDFTA-DQVDLTSALT----KKITLKTPLVSSPMDTVTEAGMAIAMA 86 Query: 69 QHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVP 121 IH + + + + Q ++ + +++ + EA Sbjct: 87 LTGGIGFIHHNCTPEFQANEVRKVKKYEQG-FITDPVVLSPKDRVRDVFEAKA 138 >4Z87-A nrPDB Length = 525 Score = 309 bits (791), Expect = 1e-84, Method: Composition-based stats. Identities = 81/281 (28%), Positives = 131/281 (46%), Gaps = 16/281 (5%) Query: 66 VMSQHSMFTAIHKHYSLDDWKLFATNHPEC---LQNVAVSSGSGQNDLEKMTSILEAVPQ 122 ++ + ++ L + + + G+ D +++ ++EA Sbjct: 216 IVDEAGCLVSMLSRTDLMKNQSYPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEA--G 273 Query: 123 VKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGP 182 + + LD + G S + +K ++ FP+ ++AGNVVT E LI +GAD +++G+G Sbjct: 274 LDVVVLDSSQGNSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGS 333 Query: 183 GSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLG 242 GS+C T+ G PQ +AV A+ I+DGG G + KA GA VM+G Sbjct: 334 GSICITQEVMACGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMG 393 Query: 243 GMFSGHTECAGEVFERNGRKLKLFYGMSSDTAMNKH--AGGVAEYR---------ASEGK 291 GM +G TE GE F R+G++LK + GM S AM K G A R ++G Sbjct: 394 GMLAGTTESPGEYFFRDGKRLKTYRGMGSIDAMQKTDVKGNAATSRYFSESDKVLVAQGV 453 Query: 292 TVEVPYKGDVENTILDILGGLRSTCTYVGAAKLKELSRRAT 332 T V KG ++ I + GL+ +C +G L E + Sbjct: 454 TGSVIDKGSIKKYIPYLYNGLQHSCQDIGVRSLVEFREKVD 494 Score = 75.5 bits (184), Expect = 3e-14, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 40/111 (36%), Gaps = 10/111 (9%) Query: 9 KLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMS 68 L + D L+ P + S E + R +K+ P + + MDTV +MA M+ Sbjct: 38 GLTYNDFLVLPGKIDFPSS-----EVVLSSRLTKKITLNAPFVSSPMDTVTEADMAIHMA 92 Query: 69 QHSMFTAIHKHYSLDDWKLFATNHPECLQ-----NVAVSSGSGQNDLEKMT 114 IH + + ++ + V V + D+ +M Sbjct: 93 LLGGIGIIHHNCTAEEQAEMVRRVKKYENGFINAPVVVGPDATVADVRRMK 143 >1JCN-A nrPDB Length = 514 Score = 308 bits (790), Expect = 2e-84, Method: Composition-based stats. Identities = 82/321 (25%), Positives = 139/321 (43%), Gaps = 24/321 (7%) Query: 16 LLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTA 75 ++ P+ + + A V L+ + +PI+ + A Sbjct: 178 VMTPRIELVVAPAGVTLKEANEILQ-RSKKGKLPIV----------------NDCDELVA 220 Query: 76 IHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYS 135 I L + + + + + + G + +K L V I LD + G S Sbjct: 221 IIARTDLKKNRDYPLASKDSQKQLLCGAAVGTREDDKYRLDLLTQAGVDVIVLDSSQGNS 280 Query: 136 EHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVG 195 + + V ++ K+P ++ GNVVT + LI +G D ++VG+G GS+C T+ G Sbjct: 281 VYQIAMVHYIKQKYPHLQVIGGNVVTAAQAKNLIDAGVDGLRVGMGCGSICITQEVMACG 340 Query: 196 YPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEV 255 PQ +AV + A+ A II+DGG G V KA GA VM+G + + TE GE Sbjct: 341 RPQGTAVYKVAEYARRFGVPIIADGGIQTVGHVVKALALGASTVMMGSLLAATTEAPGEY 400 Query: 256 FERNGRKLKLFYGMSSDTAMNKHAGGVAEY-------RASEGKTVEVPYKGDVENTILDI 308 F +G +LK + GM S AM K + Y + ++G + + KG ++ + + Sbjct: 401 FFSDGVRLKKYRGMGSLDAMEKSSSSQKRYFSEGDKVKIAQGVSGSIQDKGSIQKFVPYL 460 Query: 309 LGGLRSTCTYVGAAKLKELSR 329 + G++ C +GA L L Sbjct: 461 IAGIQHGCQDIGARSLSVLRS 481 Score = 64.7 bits (156), Expect = 5e-11, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 32/85 (37%), Gaps = 5/85 (5%) Query: 10 LDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQ 69 L + D L+ P + EVDL T ++ P+I + MDTV +MA M+ Sbjct: 30 LTYNDFLILPGFIDFIA-DEVDLTSALT----RKITLKTPLISSPMDTVTEADMAIAMAL 84 Query: 70 HSMFTAIHKHYSLDDWKLFATNHPE 94 IH + + + Sbjct: 85 MGGIGFIHHNCTPEFQANEVRKVKN 109 >4AF0-B nrPDB Length = 556 Score = 294 bits (752), Expect = 5e-80, Method: Composition-based stats. Identities = 87/332 (26%), Positives = 147/332 (44%), Gaps = 40/332 (12%) Query: 24 LKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLD 83 + + + LE+ + +PI+ +N V + Sbjct: 211 VTGSSPITLEKA-NSLLRETKKGKLPIVDSNGHLVSL--------------VARSDLLKN 255 Query: 84 DWKLFATNHPECLQ-NVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFV 142 +A+ PE Q + G+ D +++ + EA + + LD + G S + +EF+ Sbjct: 256 QNYPYASKVPESKQLYCGAAIGTRPGDKDRLKLLAEA--GLDVVVLDSSQGNSVYQIEFI 313 Query: 143 KLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAV 202 K ++ +P+ ++AGNVVT E +LI +GAD +++G+G GS+C T+ VG PQ +AV Sbjct: 314 KWIKQTYPKIDVIAGNVVTREQAAQLIAAGADGLRIGMGSGSICITQEVMAVGRPQGTAV 373 Query: 203 IECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRK 262 A+ A I+DGG G +AKA GA VM+GG+ +G TE GE F G++ Sbjct: 374 YAVAEFASRFGIPCIADGGIGNIGHIAKALALGASAVMMGGLLAGTTESPGEYFYHEGKR 433 Query: 263 LKLFYGMSSDTAMNKHAGGVAEY----------------------RASEGKTVEVPYKGD 300 +K++ GM S AM G A + ++G + +V KG Sbjct: 434 VKVYRGMGSIEAMEHTQRGSASGKRSILGLDNAATARYFSEADAVKVAQGVSGDVADKGS 493 Query: 301 VENTILDILGGLRSTCTYVGAAKLKELSRRAT 332 + + + GL+ + G + EL A Sbjct: 494 INKFVPYLFTGLQHSLQDAGIKSVSELHSCAR 525 Score = 68.2 bits (165), Expect = 5e-12, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 34/89 (38%), Gaps = 5/89 (5%) Query: 6 ADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAA 65 + L + D L+ P + ++V L+ T K P + + MDTV MA Sbjct: 56 KNGGLTYNDFLVLPGHINF-PASDVSLQSKAT----KNIVLNTPFLSSPMDTVTEDRMAI 110 Query: 66 VMSQHSMFTAIHKHYSLDDWKLFATNHPE 94 ++ H IH + S ++ + Sbjct: 111 ALALHGGLGIIHHNCSAEEQAAMVRRVKK 139 >2CU0-A nrPDB Length = 486 Score = 292 bits (748), Expect = 1e-79, Method: Composition-based stats. Identities = 94/326 (28%), Positives = 158/326 (48%), Gaps = 30/326 (9%) Query: 21 RSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKHY 80 + + +++E + +P++ VG M+ ++++ Sbjct: 158 KEVITVPESIEVEEALKIMI-ENRIDRLPVVDERGKLVGLITMSDLVAR----------- 205 Query: 81 SLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVE 140 K + + + V++ D+++ + +A V I +D A+ ++ ++ Sbjct: 206 -----KKYKNAVRDENGELLVAAAVSPFDIKRAIELDKA--GVDVIVVDTAHAHNLKAIK 258 Query: 141 FVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLS 200 +K +R K + + GN+ + V++L AD +KVG+GPGS+CTTR GVG PQ++ Sbjct: 259 SMKEMRQKV-DADFIVGNIANPKAVDDLTF--ADAVKVGIGPGSICTTRIVAGVGVPQIT 315 Query: 201 AVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNG 260 AV AD A ++I+DGG GD+ KA AGAD VMLG + +G E G+ NG Sbjct: 316 AVAMVADRAQEYGLYVIADGGIRYSGDIVKAIAAGADAVMLGNLLAGTKEAPGKEVIING 375 Query: 261 RKLKLFYGMSSDTAMNK------HAGGVAEYR--ASEGKTVEVPYKGDVENTILDILGGL 312 RK K + GM S AM K + GG + R EG VPY+G V + ++GGL Sbjct: 376 RKYKQYRGMGSLGAMMKGGAERYYQGGYMKTRKFVPEGVEGVVPYRGTVSEVLYQLVGGL 435 Query: 313 RSTCTYVGAAKLKELSRRATFIRVTQ 338 ++ YVGA ++EL + F+ +T Sbjct: 436 KAGMGYVGARNIRELKEKGEFVIITH 461 Score = 79.0 bits (193), Expect = 3e-15, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 46/120 (38%), Gaps = 6/120 (5%) Query: 6 ADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAA 65 A F DVLL P+ + ++ + +VD+ R + IPI+ A MDTV +EMA Sbjct: 11 AIKGYTFDDVLLIPQATEVEPK-DVDVST----RITPNVKLNIPILSAAMDTVTEWEMAV 65 Query: 66 VMSQHSMFTAIHKHYSLDDWKLFATNHPEC-LQNVAVSSGSGQNDLEKMTSILEAVPQVK 124 M++ IH++ +++ V ++ L + Sbjct: 66 AMAREGGLGVIHRNMGIEEQVEQVKRVKRAERLIVEDVITIAPDETVDFALFLMEKHGID 125 >4DQW-A nrPDB Length = 509 Score = 290 bits (743), Expect = 5e-79, Method: Composition-based stats. Identities = 99/332 (29%), Positives = 159/332 (47%), Gaps = 27/332 (8%) Query: 16 LLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTA 75 ++ PK + +R LE + + + ++ N G Sbjct: 171 IMTPKDKLVTAREGTPLEEMKA-KLYENRIEKMLVVDENFYLRGLVTF------------ 217 Query: 76 IHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYS 135 + A+ + V + G+G + E++ +++ A V + A+G+S Sbjct: 218 --RDIEKAKTYPLASKDEQGRLRVGAAVGTGADTGERVAALVAAGVDVVVVD--TAHGHS 273 Query: 136 EHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVG 195 + +E V+ V+ FP+ ++ GN+ T E + L +GAD +KVG+GPGS+CTTR GVG Sbjct: 274 KGVIERVRWVKQTFPDVQVIGGNIATAEAAKALAEAGADAVKVGIGPGSICTTRIVAGVG 333 Query: 196 YPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEV 255 PQ+SA+ A + G +I+DGG GD+AKA AGA VM+G MF+G E GE+ Sbjct: 334 VPQISAIANVAAALEGTGVPLIADGGIRFSGDLAKAMVAGAYCVMMGSMFAGTEEAPGEI 393 Query: 256 FERNGRKLKLFYGMSSDTAMNKHAGGV----------AEYRASEGKTVEVPYKGDVENTI 305 GR K + GM S AM+ G AE EG VPYKG + + Sbjct: 394 ELFQGRSYKSYRGMGSLGAMSGSQGSSDRYFQDASAGAEKLVPEGIEGRVPYKGALSAIV 453 Query: 306 LDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 ++GGLR+ Y G+A ++++ + F+R+T Sbjct: 454 HQLMGGLRAAMGYTGSADIQQMRTQPQFVRIT 485 Score = 86.7 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 27/94 (28%), Positives = 41/94 (43%), Gaps = 6/94 (6%) Query: 1 MPRIDADLKLDFKDVLLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGT 60 M RI L F DVLL P S + + +V L+ R ++ IP++ A MDTV Sbjct: 21 MLRISQ-EALTFDDVLLIPGYSEVLPK-DVSLKT----RLTRGIELNIPLVSAAMDTVTE 74 Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPE 94 +A M+Q IHK+ ++ + Sbjct: 75 ARLAIAMAQEGGIGIIHKNMGIEQQAAEVRKVKK 108 >1AK5-A nrPDB Length = 503 Score = 259 bits (662), Expect = 1e-69, Method: Composition-based stats. Identities = 86/333 (25%), Positives = 144/333 (43%), Gaps = 30/333 (9%) Query: 16 LLRPKRSSLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTA 75 ++ P + + + L K+ + +PII + QH + Sbjct: 166 MMTPFSKLVTAHQDTKLSEANKIIWEKKL-NALPIIDDD--------------QHLRYIV 210 Query: 76 IHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDL-EKMTSILEAVPQVKFICLDVANGY 134 K Y D ++ + + V +G D E++ +++EA +C+D ++G+ Sbjct: 211 FRKDY--DRSQVCHNELVDSQKRYLVGAGINTRDFRERVPALVEA--GADVLCIDSSDGF 266 Query: 135 SEHFVEFVKLVRAKFPEHT-IMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTG 193 SE + +R K+ + + AGN+V GE L +GAD IK+G+G GS+C TR + G Sbjct: 267 SEWQKITIGWIREKYGDKVKVGAGNIVDGEGFRYLADAGADFIKIGIGGGSICITREQKG 326 Query: 194 VGYPQLSAVIECADSAHGL------KGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSG 247 +G Q +AVI+ + + SDGG + A GADF+MLG F+ Sbjct: 327 IGRGQATAVIDVVAERNKYFEETGIYIPVCSDGGIVYDYHMTLALAMGADFIMLGRYFAR 386 Query: 248 HTECAGEVFERNGRKLKLFYGMSSDTAMNKHA---GGVAEYRASEGKTVEVPYKGDVENT 304 E NG +K ++G S A N GG + EG VPY G +++ Sbjct: 387 FEESPTRKVTINGSVMKEYWGEGSSRARNWQRYDLGGKQKLSFEEGVDSYVPYAGKLKDN 446 Query: 305 ILDILGGLRSTCTYVGAAKLKELSRRATFIRVT 337 + L ++ST GA + +L +A V+ Sbjct: 447 VEASLNKVKSTMCNCGALTIPQLQSKAKITLVS 479 Score = 48.9 bits (115), Expect = 3e-06, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 39/111 (35%), Gaps = 4/111 (3%) Query: 11 DFKDVLLRPKRSSLKS-RAEVDLER---TFTFRNSKQTYSGIPIIVANMDTVGTFEMAAV 66 F + LL P S++ + V+L F + IP++ A M +V +MA Sbjct: 11 TFNEYLLIPGLSTVDCIPSNVNLSTPLVKFQKGQQSEINLKIPLVSAIMQSVSGEKMAIA 70 Query: 67 MSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSIL 117 +++ + I S++ VS + + D + Sbjct: 71 LAREGGISFIFGSQSIESQAAMVHAVKNFKAGFVVSDSNVKPDQTFADVLA 121 >6DVI-A nrPDB Length = 394 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 43/114 (37%), Gaps = 10/114 (8%) Query: 133 GYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKT 192 G+S E + VR+ + ++ + + + SG D I G R Sbjct: 245 GHSV-TWEDIDWVRS-ITKMPVILKGIQHPDDARRAVDSGVDGIYCSNHGG-----RQAN 297 Query: 193 GVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFS 246 G G P L + E ++ ++ D G DV KA GA V +G ++ Sbjct: 298 G-GLPALDCLPEVVKASGDT--PVLFDSGIRTGADVVKALAMGASAVGIGRPYA 348 >6BFG-A nrPDB Length = 399 Score = 52.4 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 18/108 (16%) Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQL 199 E ++ +R +P ++ G +++ E + I GAD + + G QL Sbjct: 234 EALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGV-------------ILSNHGGRQL 279 Query: 200 SAVIE----CADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 I A S ++ D G D+ KA GA+ V+LG Sbjct: 280 DCAISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGR 327 >2A85-A nrPDB Length = 380 Score = 52.0 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 42/108 (38%), Gaps = 18/108 (16%) Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQL 199 E ++ +R +P ++ G +++ E + I GAD + + G QL Sbjct: 215 EALRWLRDLWPHKLLVKG-LLSAEDADRCIAEGADGV-------------ILSNHGGRQL 260 Query: 200 SAVIE----CADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 I A S ++ D G D+ KA GA+ V+LG Sbjct: 261 DCAISPMEVLAQSVAKTGKPVLIDSGFRRGSDIVKALALGAEAVLLGR 308 >5ZBN-A nrPDB Length = 371 Score = 47.8 bits (112), Expect = 7e-06, Method: Composition-based stats. Identities = 26/120 (21%), Positives = 40/120 (33%), Gaps = 22/120 (18%) Query: 142 VKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQ--- 198 V+ + I+ V+T E + +GA I + G Q Sbjct: 217 VQWL-QTITSLPILVKGVLTAEDARLAVQAGAAGI-------------IVSNHGARQLDY 262 Query: 199 ----LSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGE 254 + A+ E +A G + + DGG DV KA GA + +G GE Sbjct: 263 VPSTIMALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGASGIFIGRPVVFSLAAEGE 321 >4N6F-A nrPDB Length = 256 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 51/146 (34%), Gaps = 19/146 (13%) Query: 112 KMTSILEAVPQVKFICLDV----ANGYSEHFVEFVKLVRAK-FPEHTIMAGNVVTGEMVE 166 + IL ++ + LDV + VE + +RA+ + ++ T Sbjct: 95 RSARILRDSLGIEILKLDVRGDDNTPDNAGTVEAARELRAEGMELLPFILPDLAT---AR 151 Query: 167 ELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPG 226 L +G ++V P +G G +A+ E + + ++ +GG Sbjct: 152 ALEEAGCAALRVMASP-------VASGRGIANPAAIRELIE---QIGIPVVVEGGIGSAR 201 Query: 227 DVAKAFGAGADFVMLGGMFSGHTECA 252 VA+A GA ++ E Sbjct: 202 HVAEAMELGASATLVNTALVR-AESP 226 >1AL8-A nrPDB Length = 359 Score = 44.3 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 36/115 (31%), Gaps = 21/115 (18%) Query: 147 AKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQ-------L 199 I+ V+T E + GA I + G Q + Sbjct: 220 QTITSLPILVKGVITAEDARLAVQHGAAGI-------------IVSNHGARQLDYVPATI 266 Query: 200 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGE 254 A+ E +A G + + DGG DV KA GA V +G GE Sbjct: 267 MALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 320 >2GJN-A nrPDB Length = 328 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 14/46 (30%), Positives = 21/46 (45%) Query: 207 DSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECA 252 +A+ L+ II+ GG + A GAD + +G F EC Sbjct: 166 AAANRLRVPIIASGGFADGRGLVAALALGADAINMGTRFLATRECP 211 >2CDH-0 nrPDB Length = 226 Score = 42.4 bits (98), Expect = 3e-04, Method: Composition-based stats. Identities = 26/115 (22%), Positives = 36/115 (31%), Gaps = 21/115 (18%) Query: 147 AKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQ-------L 199 I+ V+T E + GA I + G Q + Sbjct: 104 QTITSLPILVKGVITAEDARLAVQHGAAGI-------------IVSNHGARQLDYVPATI 150 Query: 200 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGE 254 A+ E +A G + + DGG DV KA GA V +G GE Sbjct: 151 MALEEVVKAAQG-RIPVFLDGGVRRGTDVFKALALGAAGVFIGRPVVFSLAAEGE 204 >1P0K-A nrPDB Length = 349 Score = 40.8 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 25/129 (19%), Positives = 44/129 (34%), Gaps = 11/129 (8%) Query: 137 HFVEFVKLV--RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGS-------VCT 187 ++ ++ + R P G ++ +L +GA + +G G+ + Sbjct: 165 GALKRIEQICSRVSVPVIVKEVGFGMSKASAGKLYEAGAAAVDIGGYGGTNFSKIENLRR 224 Query: 188 TRTKTGVGYPQLSAVIECADSAHGLKGH-IISDGGCTCPGDVAKAFGAGADFV-MLGGMF 245 R + +S A+ +I+ GG DVAKA GA M G Sbjct: 225 QRQISFFNSWGISTAASLAEIRSEFPASTMIASGGLQDALDVAKAIALGASCTGMAGHFL 284 Query: 246 SGHTECAGE 254 T+ E Sbjct: 285 KALTDSGEE 293 >2RDU-A nrPDB Length = 387 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 41/104 (39%), Gaps = 8/104 (7%) Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQL 199 E +K +R + I+A ++ G+ E + G + I V S R GV P Sbjct: 237 EDIKWLR-RLTSLPIVAKGILRGDDAREAVKHGLNGILV-----SNHGARQLDGV--PAT 288 Query: 200 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 V+ A K + DGG DV KA GA V +G Sbjct: 289 IDVLPEIVEAVEGKVEVFLDGGVRKGTDVLKALALGAKAVFVGR 332 >3SGZ-A nrPDB Length = 352 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 15/45 (33%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 199 LSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 + A+ E + G K + DGG DV KA GA + LG Sbjct: 259 IDALREVVAAVKG-KIEVYMDGGVRTGTDVLKALALGARCIFLGR 302 >5ZKN-A nrPDB Length = 241 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 28/129 (21%), Positives = 48/129 (37%), Gaps = 21/129 (16%) Query: 122 QVKFICLDVA---NGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKV 178 V+ I +D + F+ ++ K+P MA ++ + + G DI+ Sbjct: 110 GVQIIAIDATKRERPDRKDLKNFIAEIKEKYPNQLFMA-DISSVDEALYAEKIGFDIVGT 168 Query: 179 GVGPGSVCTTRTKTGVGYPQLS----AVIECADSAHGLKGHIISDGGCTCPGDVAKAFGA 234 T VGY + A+ E +K +I++G P KA Sbjct: 169 -------------TLVGYTDYTKNYKALEELKKVVKVVKIPVIAEGNIDTPLKAKKALEI 215 Query: 235 GADFVMLGG 243 GA V++GG Sbjct: 216 GAFAVVVGG 224 >2Z6J-A nrPDB Length = 332 Score = 38.1 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 33/216 (15%), Positives = 67/216 (31%), Gaps = 16/216 (7%) Query: 36 FTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPEC 95 R ++ PI M V ++A +S+ I + + + + Sbjct: 1 MKTRITELLKIDYPIFQGGMAWVADGDLAGAVSKAGGLGIIGGGNAPKEVVKANIDKIKS 60 Query: 96 LQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIM 155 L + + I++ V + + G ++E I+ Sbjct: 61 LTDKPFGVNIMLLS-PFVEDIVDLVIEEGVKVVTTGAGNPSKYMERFHEAG------IIV 113 Query: 156 AGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGH 215 V + + + + GAD + + G + G +L+ + A + Sbjct: 114 IPVVPSVALAKRMEKIGADAV---IAEG------MEAGGHIGKLTTMTLVRQVATAISIP 164 Query: 216 IISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 +I+ GG A F GA+ V +G F E Sbjct: 165 VIAAGGIADGEGAAAGFMLGAEAVQVGTRFVVAKES 200 >2J6X-A nrPDB Length = 374 Score = 37.7 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 28/110 (25%), Positives = 39/110 (35%), Gaps = 24/110 (21%) Query: 142 VKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVG--------VGPGSVCTTRTKTG 193 ++ + A + G + E + I +GA I V PGS T Sbjct: 227 IEEIAAHSGLPVFVKG-IQHPEDADMAIKAGASGIWVSNHGARQLYEAPGSFDT------ 279 Query: 194 VGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 L A+ E + I+ D G VAKA +GAD V LG Sbjct: 280 -----LPAIAERVNKR----VPIVFDSGVRRGEHVAKALASGADVVALGR 320 >1TYG-A nrPDB Length = 253 Score = 37.7 bits (86), Expect = 0.007, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 70/200 (35%), Gaps = 28/200 (14%) Query: 64 AAVMSQHSMFTAIHKHYSL-DDWKLFATNHPECLQNVAV---SSGSGQNDLEKMTSILEA 119 A +S+ + T + ++ + + + + + + S + ++ + +A Sbjct: 29 AVAVSESDILTFAVRRMNIFEASQPNFLEQLDLSKYTLLPNTAGASTAEEAVRIARLAKA 88 Query: 120 VPQVKFICLDVANGYSEHF----VEFVKLVRAKFPEHTIM----AGNVVTGEMVEELILS 171 I ++V G S VE +K E I+ + +VV + +L Sbjct: 89 SGLCDMIKVEVI-GCSRSLLPDPVETLKASEQLLEEGFIVLPYTSDDVV---LARKLEEL 144 Query: 172 GADIIKVGVGPGSVCTTRTKTGVGYPQ-LSAVIECADSAHGLKGHIISDGGCTCPGDVAK 230 G I G P +G Q + + + K +I D G P D A Sbjct: 145 GVHAIMPGASP-----------IGSGQGILNPLNLSFIIEQAKVPVIVDAGIGSPKDAAY 193 Query: 231 AFGAGADFVMLGGMFSGHTE 250 A GAD V+L SG + Sbjct: 194 AMELGADGVLLNTAVSGADD 213 >5GVH-A nrPDB Length = 314 Score = 36.6 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 35/218 (16%), Positives = 73/218 (33%), Gaps = 18/218 (8%) Query: 35 TFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTAIHKH-YSLDDWKLFATNHP 93 T R + PI++ M GT +AA +S+ I DD + + Sbjct: 2 TVRTRVTDLLEIEHPILMGGMAWAGTPTLAAAVSEAGGLGIIGSGAMKPDDLRKAISELR 61 Query: 94 ECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHT 153 + + + +++ + K + G ++ +K K Sbjct: 62 QKTDKPFGVNIILVSPW--ADDLVKVCIEEKVPVVTFGAGNPTKYIRELKENGTKVIPV- 118 Query: 154 IMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLK 213 V + + + +GAD + + G ++G +++ + + + Sbjct: 119 -----VASDSLARMVERAGADAV---IAEG------MESGGHIGEVTTFVLVNKVSRSVN 164 Query: 214 GHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 +I+ GG +A AF GA+ V +G F E Sbjct: 165 IPVIAAGGIADGRGMAAAFALGAEAVQMGTRFVASVES 202 >3BW4-A nrPDB Length = 369 Score = 36.6 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 39/100 (39%), Gaps = 10/100 (10%) Query: 161 TGEMVEELILSGADII-----KVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGH 215 T E + +GAD + + G G+ + G G LS + + ++ + Sbjct: 154 TPEEARAVEAAGADAVIAQGVEAGGHQGTHRDSSEDDGAGIGLLSLLAQVREA---VDIP 210 Query: 216 IISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC--AG 253 +++ GG G +A AGAD LG F E G Sbjct: 211 VVAAGGIMRGGQIAAVLAAGADAAQLGTAFLATDESGAPG 250 >5LSM-A nrPDB Length = 359 Score = 35.0 bits (79), Expect = 0.044, Method: Composition-based stats. Identities = 38/184 (20%), Positives = 57/184 (30%), Gaps = 33/184 (17%) Query: 161 TGEMVEELILSGADII-----KVGVGPGSVCTTRTKTGVGY----PQLSAVIECADSAHG 211 T E L GAD I + G G + +G PQ+ A +E Sbjct: 157 TVEEALWLEARGADAIIAQGLEAGGHRGHFLSEDLTEQLGTFSLLPQIIAAVE------- 209 Query: 212 LKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSS 271 +I+ GG V A GA V +G + EC R + S Sbjct: 210 --IPVIAAGGIVDATTVRAAMTMGASAVQVGTAYLLCPECNTSAIHREALQ--------S 259 Query: 272 DTAMNKHAGGVAEYRASEGKTVE-VPYKGDVENTILDI------LGGLRSTCTYVGAAKL 324 D A + + R + G + G + + D + GLR+ +G Sbjct: 260 DAAQHTALTNLFSGRPARGIVNRFMAEMGPMNEAVPDFPLASSAVAGLRTAAERLGFWDF 319 Query: 325 KELS 328 L Sbjct: 320 SPLW 323 >4JEJ-A nrPDB Length = 244 Score = 35.0 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 25/54 (46%) Query: 192 TGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMF 245 G G + + + + ++ II GG + KA+ AGAD V++G F Sbjct: 181 AGSGAKKPVPLEMISVISQNVEIPIIVGGGIVDLHGIKKAYNAGADLVVIGTAF 234 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 90 TNHPECLQNVAVSSGSGQNDLEKMTSILEAV--PQVKFICLDVANGYSEHF-VEFVKLVR 146 + + + V+ + + + + + +A K I L+ +G + +E + ++ Sbjct: 139 SGNETAVARVSKTEPLNRENFDLALATAQAGEMLGSKLIYLEAGSGAKKPVPLEMISVIS 198 Query: 147 AKFPEHTIMAGNVVTGEMVEELILSGADIIKVG 179 I+ G +V +++ +GAD++ +G Sbjct: 199 QNVEIPIIVGGGIVDLHGIKKAYNAGADLVVIG 231 >4Q4K-A nrPDB Length = 357 Score = 35.0 bits (79), Expect = 0.051, Method: Composition-based stats. Identities = 20/97 (20%), Positives = 32/97 (32%), Gaps = 12/97 (12%) Query: 161 TGEMVEELILSGADIIKV-GVGPGSVCTTRTKTGVGYPQ-----LSAVIECADSAHGLKG 214 T E + +GAD + G+ G GV P+ + + A Sbjct: 158 TPEEAALVEAAGADAVVAQGIEAGG------HRGVFEPERGDAAIGTLALVRLLAARGSL 211 Query: 215 HIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 +++ GG + A GA V +G F E Sbjct: 212 PVVAAGGIMDGRGIRAALELGASAVQMGTAFVLCPES 248 >1VHC-A nrPDB Length = 224 Score = 34.3 bits (77), Expect = 0.090, Method: Composition-based stats. Identities = 27/104 (25%), Positives = 40/104 (38%), Gaps = 10/104 (9%) Query: 135 SEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKV-GVGPGSVCTTR---- 189 SE + ++L+RA P+ I AG V+T E V SGAD + G+ P V + Sbjct: 52 SEAAADAIRLLRANRPDFLIAAGTVLTAEQVVLAKSSGADFVVTPGLNPKIVKLCQDLNF 111 Query: 190 -TKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAF 232 GV P + + + GG + KA Sbjct: 112 PITPGVNNPMAIEIALEMGISAVKFFPAEASGGVK----MIKAL 151 >1YXY-A nrPDB Length = 234 Score = 33.9 bits (76), Expect = 0.094, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 60/149 (40%), Gaps = 11/149 (7%) Query: 109 DLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEEL 168 +++++ ++ AV + D +G F++ V+ K+P +MA ++ T + Sbjct: 93 EVDQLAALNIAVIAMDCTKRDRHDG--LDIASFIRQVKEKYPNQLLMA-DISTFDEGLVA 149 Query: 169 ILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDV 228 +G D + + G +R + G + A+ + +I++G P + Sbjct: 150 HQAGIDFVGTTL-SGYTPYSRQEAGPDVALIEALCKA-------GIAVIAEGKIHSPEEA 201 Query: 229 AKAFGAGADFVMLGGMFSGHTECAGEVFE 257 K G +++GG + E A E Sbjct: 202 KKINDLGVAGIVVGGAITRPKEIAERFIE 230 >3SR7-A nrPDB Length = 365 Score = 33.5 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 14/27 (51%) Query: 213 KGHIISDGGCTCPGDVAKAFGAGADFV 239 K I++ GG P D+ KA GA V Sbjct: 278 KVEILASGGIRHPLDIIKALVLGAKAV 304 >1MXS-A nrPDB Length = 225 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 11/42 (26%), Positives = 24/42 (57%) Query: 135 SEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADII 176 S+H ++ ++++R + PE + AG V+ M + +GA + Sbjct: 61 SQHGLKAIQVLREQRPELCVGAGTVLDRSMFAAVEAAGAQFV 102 >1N7K-A nrPDB Length = 234 Score = 33.1 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 27/69 (39%), Gaps = 10/69 (14%) Query: 171 SGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAK 230 +GADI+K G T G P V A A L + + GG D Sbjct: 160 AGADIVKTSTG--------VYTKGGDP--VTVFRLASLAKPLGMGVKASGGIRSGIDAVL 209 Query: 231 AFGAGADFV 239 A GAGAD + Sbjct: 210 AVGAGADII 218 >1H1Z-A nrPDB Length = 228 Score = 32.3 bits (72), Expect = 0.32, Method: Composition-based stats. Identities = 25/164 (15%), Positives = 55/164 (33%), Gaps = 13/164 (7%) Query: 23 SLKSRAEVDLERTFTFRNSKQTYSGIPIIVANMDTVGTFEMAAVMSQHSMFTA-IHKHYS 81 + + R + Y ++V N + +++ H S Sbjct: 44 HFVPNLTIGAPVIQSLRKHTKAYLDCHLMVTN-----PSDYVEPLAKAGASGFTFHIEVS 98 Query: 82 LDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDV------ANGYS 135 D+W+ + VS G +E++ ++EA V+ + + + Sbjct: 99 RDNWQELIQSIKAKGMRPGVSLRPGT-PVEEVFPLVEAENPVELVLVMTVEPGFGGQKFM 157 Query: 136 EHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVG 179 +E V+ +R K+P I + ++ +GA+ I G Sbjct: 158 PEMMEKVRALRKKYPSLDIEVDGGLGPSTIDVAASAGANCIVAG 201 >1QAP-A nrPDB Length = 296 Score = 32.0 bits (71), Expect = 0.36, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 34/72 (47%), Gaps = 6/72 (8%) Query: 109 DLEKMTSILEAV-PQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEE 167 ++E + + +A+ I LD N ++ E VK V + ++GNV T E + E Sbjct: 214 EVENLDELDDALKAGADIIMLD--NFNTDQMREAVKRVNGQ--ARLEVSGNV-TAETLRE 268 Query: 168 LILSGADIIKVG 179 +G D I VG Sbjct: 269 FAETGVDFISVG 280 >2ZRW-A nrPDB Length = 368 Score = 32.0 bits (71), Expect = 0.39, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 18/46 (39%), Gaps = 8/46 (17%) Query: 195 GYPQLSAVIECADSAHGLKGH---IISDGGCTCPGDVAKAFGAGAD 237 G P ++++E ++ GG D AKA GAD Sbjct: 251 GVPTAASIMEV-----RYSVPDSFLVGSGGIRSGLDAAKAIALGAD 291 >3F4W-A nrPDB Length = 211 Score = 32.0 bits (71), Expect = 0.40, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 32/84 (38%), Gaps = 18/84 (21%) Query: 139 VEFVKLVRAKFPEHTIMA-GNVVTGEMVEE--LILSGADIIKVGVGPGSVCTTRTKTGVG 195 V +K ++ K+P ++A ++ G E L +GAD + V +G Sbjct: 41 VNAIKAIKEKYPHKEVLADAKIMDGGHFESQLLFDAGADYVTV---------------LG 85 Query: 196 YPQLSAVIECADSAHGLKGHIISD 219 + + C +A ++ D Sbjct: 86 VTDVLTIQSCIRAAKEAGKQVVVD 109 >5Z9Y-A nrPDB Length = 252 Score = 31.2 bits (69), Expect = 0.72, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 18/54 (33%), Gaps = 3/54 (5%) Query: 190 TKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 TG+G + A ++ D G D A A G D V+L Sbjct: 158 IGTGLGIANPHNIEMIVAGAR---VPVVLDAGIGTASDAALAMELGCDAVLLAS 208 >1SZG-A nrPDB Length = 511 Score = 31.2 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 14/30 (46%) Query: 216 IISDGGCTCPGDVAKAFGAGADFVMLGGMF 245 + DGG DV KA GA V LG F Sbjct: 406 VFVDGGVRRGTDVLKALCLGAKGVGLGRPF 435 >1EP3-A nrPDB Length = 311 Score = 30.8 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 18/42 (42%) Query: 201 AVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLG 242 A+ A + II GG DV + + AGA V +G Sbjct: 229 ALKLIHQVAQDVDIPIIGMGGVANAQDVLEMYMAGASAVAVG 270 Score = 28.9 bits (63), Expect = 3.9, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 43/116 (37%), Gaps = 9/116 (7%) Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELI-------LSGADIIKVGVGPGSVCTTRTKT 192 E + + FPE I+A NV E + + + I++ + +V Sbjct: 87 EKLPWLNENFPELPIIA-NVAGSEEADYVAVCAKIGDAANVKAIELNISCPNVKHGGQAF 145 Query: 193 GVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAF-GAGADFVMLGGMFSG 247 G +A+++ + + ++ T +AKA AGAD + + G Sbjct: 146 GTDPEVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEAAGADGLTMINTLMG 201 >1QCW-A nrPDB Length = 410 Score = 30.8 bits (68), Expect = 0.86, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 14/30 (46%) Query: 216 IISDGGCTCPGDVAKAFGAGADFVMLGGMF 245 + DGG DV KA GA V LG F Sbjct: 305 VFVDGGVRRGTDVLKALCLGAKGVGLGRPF 334 >6CTY-A nrPDB Length = 372 Score = 30.8 bits (68), Expect = 0.88, Method: Composition-based stats. Identities = 27/147 (18%), Positives = 52/147 (35%), Gaps = 22/147 (14%) Query: 108 NDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEE 167 ++K+ L +V +D+ + + + ++ +R KFPE I+ ++ T + + Sbjct: 152 EQMQKIGMPLLIHGEVTDAAVDIFDREARFIDQILEPIRQKFPELKIVFEHITTKDAADY 211 Query: 168 LILSGADIIKVGVGPGSVCTTRTKTGVG--YPQLSAVIECADSAHGLKGHIISDGGCTCP 225 +L+G + V P + R VG P L + S H Sbjct: 212 -VLAGNRFLGATVTPQHLMFNRNHMLVGGIRPHLFCLPILKRSTHQQA------------ 258 Query: 226 GDVAKAFGAGADFVMLGGMFSGHTECA 252 + A +G+D F G Sbjct: 259 --LRAAVASGSD-----RFFLGTDSAP 278 >1WV2-A nrPDB Length = 265 Score = 30.8 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 42/127 (33%), Gaps = 19/127 (14%) Query: 132 NGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIK------------VG 179 +G++ +E + + FP V T + E+L+ G D++ Sbjct: 101 DGHNLVKLEVLADQKTLFPNV------VETLKAAEQLVKDGFDVMVYTSDDPIIARQLAE 154 Query: 180 VGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFV 239 +G +V G G + K ++ D G D A A G + V Sbjct: 155 IGCIAVMPLAGLIGSGLG-ICNPYNLRIILEEAKVPVLVDAGVGTASDAAIAMELGCEAV 213 Query: 240 MLGGMFS 246 ++ + Sbjct: 214 LMNTAIA 220 >5UE9-A nrPDB Length = 306 Score = 30.8 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 40/186 (21%), Positives = 72/186 (38%), Gaps = 25/186 (13%) Query: 82 LDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVA-----NGYSE 136 + + + + L +A +GS ++D + + + P VK I L+++ +G Sbjct: 81 MAEKLPWLNENFPDLPIIANVAGSEEDDYVAVCAKIGDAPNVKVIELNISCPNVKHGGQA 140 Query: 137 HFVE------FVKLVRA--KFPEHTIMAGNVVT-GEMVEELILSGADI---IKVGVGPGS 184 + VK +A K P + ++ NV + + + +GAD I +G Sbjct: 141 FGTDPDVAAALVKACKAVSKVPLYVKLSPNVTDIVPIAKAVEAAGADGLTMINTLMGVRF 200 Query: 185 VCTTR------TKTGVGYPQL--SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGA 236 TR G+ P + A+ A + II GG DV + + AGA Sbjct: 201 DLKTRKPVLANITGGLSGPAIKPVALKLIHQVAQVVDIPIIGMGGVESAQDVLEMYMAGA 260 Query: 237 DFVMLG 242 V +G Sbjct: 261 SAVAVG 266 >6NKE-A nrPDB Length = 252 Score = 30.8 bits (68), Expect = 0.98, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 21/53 (39%) Query: 192 TGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGM 244 G G P+ + + + +I GG P + AGAD ++ G + Sbjct: 173 AGSGAPRPVSEDTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTGSI 225 Score = 28.5 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 20/40 (50%) Query: 140 EFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVG 179 + + V++K I+ G + E + L+GAD+I G Sbjct: 184 DTISYVKSKINIPLIVGGGIRDPETAMRIALAGADMIVTG 223 >1YTE-A nrPDB Length = 398 Score = 30.4 bits (67), Expect = 1.1, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 40/104 (38%), Gaps = 6/104 (5%) Query: 81 SLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQVKFICLDVA---NGYSEH 137 + WKL N ++V + + ++ I E +V +I LD G E Sbjct: 196 DEEAWKLTLENTKNGQKSVLL-IDTYMDEKFAAIKIAEMFDKVDYIRLDTPSSRRGNFEA 254 Query: 138 FVEFVKLVRAKFP--EHTIMAGNVVTGEMVEELILSGADIIKVG 179 + V+ A + IM + V++L +GA+ VG Sbjct: 255 LIREVRWELALRGRSDIKIMVSGGLDENTVKKLREAGAEAFGVG 298 >3O07-A nrPDB Length = 291 Score = 30.4 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 15/36 (41%) Query: 146 RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 + K P AG V T L+ G D + VG G Sbjct: 196 KGKLPVVNFAAGGVATPADAALLMQLGCDGVFVGSG 231 >2ZBT-A nrPDB Length = 297 Score = 30.4 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 13/44 (29%), Positives = 17/44 (38%), Gaps = 2/44 (4%) Query: 140 EFVKLVRAK--FPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 E VK V P AG + T ++ G D + VG G Sbjct: 197 ELVKWVHDHGRLPVVNFAAGGIATPADAALMMHLGMDGVFVGSG 240 >2A1T-A nrPDB Length = 421 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 25/72 (34%), Gaps = 5/72 (6%) Query: 201 AVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNG 260 A E I+ GD+A A ++ G F +TE E R+ Sbjct: 340 AAWEVDSGRRNTYYASIAKA---FAGDIANQLATDAVQILGGNGF--NTEYPVEKLMRDA 394 Query: 261 RKLKLFYGMSSD 272 + +++ G S Sbjct: 395 KIYQIYEGTSQI 406 >2ISS-A nrPDB Length = 313 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 139 VEFVKLVRA--KFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 VE ++ V+ + P AG V T +++ GAD + VG G Sbjct: 214 VELLREVKRLGRLPVVNFAAGGVATPADAALMMMLGADGVFVGSG 258 >4WY0-A nrPDB Length = 305 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 21/45 (46%), Gaps = 2/45 (4%) Query: 139 VEFVKLVRA--KFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 VE ++ ++ + P AG V T ++ GAD + VG G Sbjct: 203 VEVLREIKRLGRLPVVNFAAGGVTTPADAALMMHLGADGVFVGSG 247 Score = 28.1 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 16/49 (32%), Positives = 21/49 (42%), Gaps = 3/49 (6%) Query: 198 QLSAVIECADSAHGLK-GHII--SDGGCTCPGDVAKAFGAGADFVMLGG 243 QL A +E L ++ + GG T P D A GAD V +G Sbjct: 198 QLGAPVEVLREIKRLGRLPVVNFAAGGVTTPADAALMMHLGADGVFVGS 246 >1EUA-A nrPDB Length = 213 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 25/49 (51%), Gaps = 3/49 (6%) Query: 135 SEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPG 183 +E V+ ++ + + PE + AG V+ + + E+ +GA + PG Sbjct: 50 TECAVDAIRAIAKEVPEAIVGAGTVLNPQQLAEVTEAGAQF---AISPG 95 >4MM1-A nrPDB Length = 250 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 27/81 (33%), Gaps = 7/81 (8%) Query: 192 TGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTEC 251 G G P+ A +I GG D A+ GAGAD V+ G + Sbjct: 175 AGSGAPEHVPEEMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTGTVVENSDN- 233 Query: 252 AGEVFERNGRKLKLFYGMSSD 272 + ++ GM S Sbjct: 234 ------VEDKIREIVEGMGSV 248 Score = 28.1 bits (61), Expect = 6.3, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 29/60 (48%), Gaps = 1/60 (1%) Query: 121 PQVKFICLDVANGYSEHF-VEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVG 179 ++ L+ +G EH E + LV+ + I+ G + +GE + +GAD++ G Sbjct: 166 LGMRLFYLEAGSGAPEHVPEEMIALVKRCTDQILIVGGGIRSGEDAARVAGAGADVVVTG 225 >4NU7-A nrPDB Length = 246 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 19/99 (19%), Positives = 40/99 (40%), Gaps = 8/99 (8%) Query: 89 ATNHPECLQNVAVSSGSGQNDLEKMTSILEAVPQ-----VKFICLDVANGYSEHFVEFVK 143 A + +Q + +G K + EA+ + + ++ G + + ++ Sbjct: 106 AAELAKRIQARGIKAGLAIKPATKFEDLGEALAGDNFDMLLVMTVEPGFGGQKFMADMLQ 165 Query: 144 LVR---AKFPEHTIMAGNVVTGEMVEELILSGADIIKVG 179 VR + FP+ I + GE V+ +GA++I G Sbjct: 166 KVRTARSLFPKLNIQVDGGLDGETVKPAASAGANVIVAG 204 >4XBS-A nrPDB Length = 265 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 31/75 (41%), Gaps = 3/75 (4%) Query: 106 GQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIM--AGNVVTGE 163 ++++ + + E F+ S VE VKL+R + + +G + + E Sbjct: 174 TKDEIVRACQLSE-KAGADFVKTSTGFSTSGAKVEDVKLMRETVGDRLGVKASGGIHSRE 232 Query: 164 MVEELILSGADIIKV 178 +I +GA + V Sbjct: 233 EALAMIDAGASRMGV 247 >3OIX-A nrPDB Length = 345 Score = 29.6 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 26/68 (38%), Gaps = 5/68 (7%) Query: 200 SAVIECADSAHGLK--GHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFE 257 +A+ L II GG D + GA V +G H E ++F+ Sbjct: 260 TALANVHAFYKRLNPSIQIIGTGGVKTGRDAFEHILCGASMVQIGTAL--HQEGP-QIFK 316 Query: 258 RNGRKLKL 265 R ++LK Sbjct: 317 RITKELKA 324 >1XI3-A nrPDB Length = 215 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 42/110 (38%), Gaps = 7/110 (6%) Query: 113 MTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSG 172 ++ +V A+G + V + + I+ +V + E E G Sbjct: 69 YDALFFVDDRVDVALAVDADGVQLGPEDMPIEVAKEIAPNLIIGASVYSLEEALEAEKKG 128 Query: 173 ADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGC 222 AD + G GSV T+TK L + + +S +K +++ GG Sbjct: 129 ADYL----GAGSVFPTKTKEDARVIGLEGLRKIVES---VKIPVVAIGGI 171 >1KA9-F nrPDB Length = 252 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 20/87 (22%), Positives = 31/87 (35%), Gaps = 6/87 (6%) Query: 146 RAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIEC 205 R FPE + G V TG E + G + +G G + T G + + Sbjct: 135 RGDFPEVHVAGGRVPTGLHAVEWAVKGVE-----LGAGEILLTSMDRD-GTKEGYDLRLT 188 Query: 206 ADSAHGLKGHIISDGGCTCPGDVAKAF 232 A + +I+ GG +AF Sbjct: 189 RMVAEAVGVPVIASGGAGRMEHFLEAF 215 Score = 28.9 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 33/111 (29%), Gaps = 23/111 (20%) Query: 146 RAKFPEHTIMAGNVVTG-------------EMVEELILSGADIIKVGVGPGSVCTTRTKT 192 + P + AG VV G E +GAD + + T + Sbjct: 5 KRIVPCLDVHAGRVVKGVNFVNLRDAGDPVEAARAYDEAGADELVFL----DISATHEER 60 Query: 193 GVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 + + A A + + GG D K +GAD V + Sbjct: 61 AI------LLDVVARVAERVFIPLTVGGGVRSLEDARKLLLSGADKVSVNS 105 >2NV2-A nrPDB Length = 294 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 15/34 (44%) Query: 148 KFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 K P AG V T ++ GAD + VG G Sbjct: 204 KLPVVNFAAGGVATPADAALMMQLGADGVFVGSG 237 >6HYE-A nrPDB Length = 314 Score = 29.6 bits (65), Expect = 2.2, Method: Composition-based stats. Identities = 12/49 (24%), Positives = 20/49 (40%), Gaps = 3/49 (6%) Query: 198 QLSAVIECADSAHGLK-GHII--SDGGCTCPGDVAKAFGAGADFVMLGG 243 ++SA + + ++ + GG T P D A G D V +G Sbjct: 209 KISAPYDLVAQTKQMGRVPVVQFASGGITTPADAALMMQLGCDGVFVGS 257 >4UTT-A nrPDB Length = 229 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 17/32 (53%) Query: 212 LKGHIISDGGCTCPGDVAKAFGAGADFVMLGG 243 +K +I +G P ++ KA GA ++GG Sbjct: 182 VKIPVICEGRINTPEELKKALDLGAYSAVVGG 213 >3BIC-A nrPDB Length = 762 Score = 29.3 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 24/137 (17%), Positives = 42/137 (30%), Gaps = 24/137 (17%) Query: 71 SMFTAIHKHYSLDDWKL---FATNHPECLQNVAVSSGSGQND----------LEKMTSIL 117 S +HK + + A + A +G D + + Sbjct: 589 SAIKRVHKFMEREGRRPRLLVAKMGQDGHDRGAKVIATGFADLGFDVDIGPLFQTPREVA 648 Query: 118 EAVPQVKFICLDV---ANGYSEHFVEFVKLVRAK-FPEHTIMAGNVVTGEMVEELILSGA 173 + + V A G+ E +K + + P+ +M G V+ + E L G Sbjct: 649 QQAVDADVHAVGVSTLAAGHKTLVPELIKELNSLGRPDILVMCGGVIPPQDYEFLFEVGV 708 Query: 174 DIIKVGVGPGSVCTTRT 190 + GPG TR Sbjct: 709 SNV---FGPG----TRI 718 >2P8U-A nrPDB Length = 478 Score = 29.3 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 12/99 (12%), Positives = 33/99 (33%), Gaps = 10/99 (10%) Query: 94 ECLQNVAVSSGSGQNDLEKMT----SILEAVPQVKFICLDVAN---GYSEHFVEFVKLVR 146 +C+ + V + + + + + + E +D N G + V + Sbjct: 93 DCIGRLEVGTETIIDKSKSVKTNLMQLFEESGNTDIEGIDTTNACYGGTAAVFNAVNWIE 152 Query: 147 AKFPE---HTIMAGNVVTGEMVEELILSGADIIKVGVGP 182 + + ++AG++ G + + +GP Sbjct: 153 SSSWDGRYALVVAGDIAVYATGNARPTGGVGAVALLIGP 191 >4HDR-A nrPDB Length = 348 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 16/82 (19%), Positives = 31/82 (37%) Query: 122 QVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 + +D+ +V + + + G +T E + + +G DI+ V Sbjct: 109 GADMVVVDMGVAGDLSYVPGLWHRKIAYGTQDFTEGPAMTREQAIQAVETGIDIVNDRVK 168 Query: 182 PGSVCTTRTKTGVGYPQLSAVI 203 G+ C + G+G SA I Sbjct: 169 HGNRCFCLGEMGIGNTTSSATI 190 >4IQL-A nrPDB Length = 333 Score = 29.3 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 63/204 (30%), Gaps = 16/204 (7%) Query: 49 PIIVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQN 108 PII M +++A+ +S I D + + Sbjct: 33 PIISGGMVWCSGWKLASAVSNCGGLGLIGAGSMHPDNLEHHIRSCKAATDKPFGVNV-PL 91 Query: 109 DLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEEL 168 +M I+E + + + + G + + +K +K V + + Sbjct: 92 LYPEMDKIMEIIMREHVPVVVTSAGSPKVWTAKLKAAGSKVIHV------VSSATFARKS 145 Query: 169 ILSGADIIKV-GVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGCTCPGD 227 +G D I G G G + + + + + +++ GG Sbjct: 146 EAAGVDAIVAEGFEAGG--------HNGREETTTLCLIPEVVDAVNIPVVAAGGIASGRA 197 Query: 228 VAKAFGAGADFVMLGGMFSGHTEC 251 VA A GAD V +G F+ E Sbjct: 198 VAAALALGADAVQVGTRFALSEES 221 >2HTM-A nrPDB Length = 268 Score = 28.9 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 36/110 (32%), Gaps = 11/110 (10%) Query: 143 KLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAV 202 +L+ F M ++V + + L + + +G G TR A+ Sbjct: 119 RLIEEDFLVLPYMGPDLVLAKRLAALGTATVMPLAAPIGSGWGVRTR-----------AL 167 Query: 203 IECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECA 252 +E ++ D G P A+ G D V++ + + Sbjct: 168 LELFAREKASLPPVVVDAGLGLPSHAAEVMELGLDAVLVNTAIAEAQDPP 217 >4ADT-A nrPDB Length = 297 Score = 28.9 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 34/88 (38%), Gaps = 8/88 (9%) Query: 102 SSGSGQNDLEKMTSILEAVPQVKFIC-LDVANGYS-----EHFVEFVKLVRA--KFPEHT 153 N +E + I ++K++C LD + Y+ ++ + L R + P Sbjct: 153 GEAGTGNIIEAIKHIRTVNNEIKYLCSLDESEVYNFAKKLRAPIDLILLTRKLKRLPVVN 212 Query: 154 IMAGNVVTGEMVEELILSGADIIKVGVG 181 AG + T + G D + VG G Sbjct: 213 FAAGGIATPADAAMCMQLGMDGVFVGSG 240 >3W7D-A nrPDB Length = 313 Score = 28.9 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 18/81 (22%), Positives = 25/81 (30%), Gaps = 14/81 (17%) Query: 200 SAVIECADSAHGLKGHIISDGGCTCPG-DVAKAFGAGADFVMLGGMFSGHTECAG----- 253 +A+ ++ G G D AGA V +G E G Sbjct: 229 TALANVNAFYRRCPDKLVFGCGGVYSGEDAFLHILAGASMVQVGTAL--QEEGPGIFTRL 286 Query: 254 -----EVFERNG-RKLKLFYG 268 E+ R G R L+ F G Sbjct: 287 EDELLEIMARKGYRTLEEFRG 307 >4X2R-A nrPDB Length = 250 Score = 28.5 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 15/80 (18%), Positives = 27/80 (33%), Gaps = 11/80 (13%) Query: 163 EMVEELILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIISDGGC 222 E + + +GA+ I + G + ++E + + GG Sbjct: 37 EAARDWVEAGAEWIHL---------VDLDAAFGRGSNAPLLE--RIVGEVGIKVELSGGI 85 Query: 223 TCPGDVAKAFGAGADFVMLG 242 + +A AGA V LG Sbjct: 86 RDDASLTRALKAGAARVNLG 105 >1Y0E-A nrPDB Length = 223 Score = 28.5 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 57/206 (27%), Gaps = 35/206 (16%) Query: 61 FEMAAVMSQHSMFTAIHKHYSLDDWKLFATNHPECLQNVAVSSGSGQNDLEKMTSILEAV 120 +MA + + + L + G + D + + A Sbjct: 26 SKMALAAYEGGAVGI---RANTKEDILAIKETVD-----LPVIGIVKRDYDHSDVFITAT 77 Query: 121 P---------QVKFICLDVA--NGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELI 169 Q + I LD E E V +R P IMA ++ T E + Sbjct: 78 SKEVDELIESQCEVIALDATLQQRPKETLDELVSYIRTHAPNVEIMA-DIATVEEAKNAA 136 Query: 170 LSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIE-----CADSAHGLKGHIISDGGCTC 224 G D I T Y Q + + D + +I++G Sbjct: 137 RLGFDYIG----------TTLHGYTSYTQGQLLYQNDFQFLKDVLQSVDAKVIAEGNVIT 186 Query: 225 PGDVAKAFGAGADFVMLGGMFSGHTE 250 P + G ++GG + E Sbjct: 187 PDMYKRVMDLGVHCSVVGGAITRPKE 212 >5UMF-A nrPDB Length = 235 Score = 28.5 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 1/50 (2%) Query: 198 QLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSG 247 Q+ A+++ + G + I DGG ++A AGAD + G G Sbjct: 167 QVRAMLDRYEGKSGRRIAIEVDGGIKTD-NIAAVARAGADTFVAGSAIFG 215 >3MDE-A nrPDB Length = 385 Score = 28.5 bits (62), Expect = 5.0, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 19/49 (38%), Gaps = 2/49 (4%) Query: 224 CPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLFYGMSSD 272 D+A A V G F +TE E R+ + +++ G + Sbjct: 325 YAADIANQLATDAVQVFGGNGF--NTEYPVEKLMRDAKIYQIYEGTAQI 371 >2GGG-A nrPDB Length = 375 Score = 28.1 bits (61), Expect = 5.4, Method: Composition-based stats. Identities = 9/39 (23%), Positives = 17/39 (43%) Query: 202 VIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVM 240 +++ A+ A ++ + D D KA GA V+ Sbjct: 228 LVDHAELARRIRTPLCLDESVASASDARKALALGAGGVI 266 >1H5Y-A nrPDB Length = 253 Score = 28.1 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 16/43 (37%) Query: 197 PQLSAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFV 239 + + + A + ++ GG D F AGAD V Sbjct: 61 GRATFIDSVKRVAEAVSIPVLVGGGVRSLEDATTLFRAGADKV 103 >1JUE-A nrPDB Length = 311 Score = 28.1 bits (61), Expect = 6.1, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 18/55 (32%), Gaps = 4/55 (7%) Query: 200 SAVIECADSAHGLK--GHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECA 252 +A+ LK II GG D + GA + +G H E Sbjct: 227 TALANVRAFYTRLKPEIQIIGTGGIETGQDAFEHLLCGATMLQIGTAL--HKEGP 279 >5EY5-A nrPDB Length = 273 Score = 27.7 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 10/20 (50%), Positives = 16/20 (80%) Query: 161 TGEMVEELILSGADIIKVGV 180 T E+V L+ +GADII++G+ Sbjct: 33 TLELVRALVEAGADIIELGI 52 >6DU6-A nrPDB Length = 565 Score = 27.7 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 30/172 (17%), Positives = 58/172 (33%), Gaps = 23/172 (13%) Query: 108 NDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEE 167 ++ +K V I + + ++ ++ + + ++ + + + ++ Sbjct: 238 SEKDKSDLQFGVEQGVDVIF--ASFIRNAAALKEIRTILGEKGKNIKIISKIENQQGMQN 295 Query: 168 L--ILSGADIIKVGVGPGSVCTTRTKTGVGYPQLSAVIECADSAHGLKGHIIS-----DG 220 L I++ +D I V G + K V Q S + C + +I + Sbjct: 296 LDAIIAASDGIMVARGDLGIEIPAEK--VFLAQKSMIARC----NRAGKPVICATQMLES 349 Query: 221 GCTCP-------GDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKL 265 P DVA A GAD VML G + E E + K Sbjct: 350 MIKKPRPTRAEISDVANAIIDGADCVMLSGETA-KGEYPLECVLTMAKTCKE 400 >4AXK-A nrPDB Length = 250 Score = 27.7 bits (60), Expect = 6.9, Method: Composition-based stats. Identities = 14/57 (24%), Positives = 21/57 (36%) Query: 206 ADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRK 262 A+ L + GG + +A GA V +G E +V R+G K Sbjct: 67 AEITRQLDIKVELTGGIRDDASLERALATGATRVNIGTAALEKPEWIADVIRRHGEK 123 >5G1T-A nrPDB Length = 256 Score = 27.7 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 18/89 (20%), Positives = 34/89 (38%), Gaps = 3/89 (3%) Query: 106 GQNDLEKMTSILEAVPQVKFIC-LDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEM 164 G + L ++ V + L A ++ + +K + A + G V T E Sbjct: 31 GNDPLPRLQDYAAQGAGVLHLVDLTGAKDPAKRQIPLIKTLVAGVNVPVQVGGGVRTEED 90 Query: 165 VEELILSGADIIKVGVGPGSVCTTRTKTG 193 V L+ +G +V +G +V + G Sbjct: 91 VAALLKAGV--ARVVIGSTAVKSPDVVKG 117 >3OA3-A nrPDB Length = 288 Score = 27.7 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 23/89 (25%) Query: 153 TIMAGNVVTGEMVEELILSGADIIKVGVG---PG-SVCTTRTKTGVGYPQLSAVIECADS 208 I+AG V++ L+GAD +K G PG S+ +SAV + S Sbjct: 189 EIIAGCVLSS-------LAGADYVKTSTGFNGPGASI--------ENVSLMSAVCDSLQS 233 Query: 209 AHGLKGHIISDGGCTCPGDVAKAFGAGAD 237 +K + GG D K AGA+ Sbjct: 234 ETRVK----ASGGIRTIEDCVKMVRAGAE 258 >4EVZ-A nrPDB Length = 258 Score = 27.7 bits (60), Expect = 8.5, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 17/42 (40%) Query: 200 SAVIECADSAHGLKGHIISDGGCTCPGDVAKAFGAGADFVML 241 + + +A + + GG D ++ AGAD V + Sbjct: 61 TMLEVVERTAEQVFIPLTVGGGIRSVEDASRLLRAGADKVSI 102 >1OFP-A nrPDB Length = 370 Score = 27.3 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 26/149 (17%), Positives = 49/149 (32%), Gaps = 8/149 (5%) Query: 34 RTFTFRNSKQTYSGIPI-IVANMDTVGTFEMAAVMSQHSMFTAIHKHYSLDDWKLFATNH 92 RT + ++ SG+ + T GT +A Q + + H + + A Sbjct: 180 RTTESQLHRELASGLSFPVGFKNGTDGTLNVAVDACQAAAHS--HHFMGVTKHGVAAITT 237 Query: 93 PECLQNVAVSS-----GSGQNDLEKMTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRA 147 + ++ V G+ + + + + +D ++G S V Sbjct: 238 TKGNEHCFVILRGGKKGTNYDAKSVAEAKAQLPAGSNGLMIDYSHGNSNKDFRNQPKVND 297 Query: 148 KFPEHTIMAGNVVTGEMVEELILSGADII 176 E N +TG M+E I G I Sbjct: 298 VVCEQIANGENAITGVMIESNINEGNQGI 326 >3L9X-A nrPDB Length = 413 Score = 27.3 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 36/104 (34%), Gaps = 10/104 (9%) Query: 59 GTFEMAAVMSQHSMFTAIHKHYSLDDWKLFAT-----NHPECLQNVAVSSGSGQND-LEK 112 G+ M +++ F I L +H E L+ + G ++ Sbjct: 1 GSHGMRVIIAGFGRFGQITGRLLLSSGVKMVVLDHDPDHIETLRKFGMKVFYGDATRMDL 60 Query: 113 MTSILEAVPQVKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMA 156 + S A +V +D ++ ++V+ FP I+A Sbjct: 61 LESAGAAKAEVLINAIDDPQTN----LQLTEMVKEHFPHLQIIA 100 >4N02-A nrPDB Length = 357 Score = 27.3 bits (59), Expect = 9.1, Method: Composition-based stats. Identities = 9/27 (33%), Positives = 12/27 (44%) Query: 213 KGHIISDGGCTCPGDVAKAFGAGADFV 239 K ++ GG P D+ K GA V Sbjct: 266 KVELLVSGGVRNPLDMIKCLVFGAKAV 292 >5LNS-A nrPDB Length = 316 Score = 27.3 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 14/34 (41%) Query: 148 KFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 + P AG V T ++ G D + VG G Sbjct: 220 RLPVVQFAAGGVATPADAALMMQLGCDGVFVGSG 253 >2W6R-A nrPDB Length = 266 Score = 27.3 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 15/53 (28%), Positives = 22/53 (41%), Gaps = 8/53 (15%) Query: 214 GHIISDGGCTCPGDVAKAFGAGADFVMLGGMFSGHTECAGEVFERNGRKLKLF 266 II+ GG +AF AGAD + +F E + R+LK + Sbjct: 75 LPIIASGGAGKMEHFLEAFLAGADKALAASVF--------HFREIDMRELKEY 119 >4B2O-A nrPDB Length = 286 Score = 27.3 bits (59), Expect = 9.4, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 7/49 (14%) Query: 138 FVEFVKLVRAKF-PEHTIMAG-NVVTGEMVEE-----LILSGADIIKVG 179 E+V ++ K+ P TI+ G N G+ + E LI SGAD I +G Sbjct: 18 VKEYVPKLKTKYKPHFTIINGENAAHGKGLTEKIYHSLIQSGADAITMG 66 >2YZR-A nrPDB Length = 330 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 15/34 (44%) Query: 148 KFPEHTIMAGNVVTGEMVEELILSGADIIKVGVG 181 + P AG V T ++ G+D + VG G Sbjct: 240 RLPVVNFAAGGVATPADAALMMQLGSDGVFVGSG 273 >3TI8-A nrPDB Length = 395 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 41/112 (36%), Gaps = 9/112 (8%) Query: 123 VKFICLDVANGYSEHFVEFVKLVRAKFPEHTIMAGNVVTGEMVEELILSGADIIKVGVGP 182 V+ +C D NG + + F + + + AG V++ +G+ VG Sbjct: 207 VECVCRDNWNGMNRPILIFDEDLDYEVGYLC--AGIPTDTPRVQDSSFTGSCTNAVG--- 261 Query: 183 GSVCTTRTKTGVGYPQLSAVIE----CADSAHGLKGHIISDGGCTCPGDVAK 230 GS G G+ Q ++V S G + +I DG + K Sbjct: 262 GSGTNNYGVKGFGFRQGNSVWAGRTVSISSRSGFEILLIEDGWIRTSKTIVK 313 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.134 0.357 Lambda K H 0.267 0.0407 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,674,754 Number of Sequences: 36641 Number of extensions: 518389 Number of successful extensions: 2166 Number of sequences better than 10.0: 151 Number of HSP's better than 10.0 without gapping: 117 Number of HSP's successfully gapped in prelim test: 69 Number of HSP's that attempted gapping in prelim test: 1833 Number of HSP's gapped (non-prelim): 266 length of query: 345 length of database: 10,336,785 effective HSP length: 98 effective length of query: 247 effective length of database: 6,745,967 effective search space: 1666253849 effective search space used: 1666253849 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.3 bits)