BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P36421 (394 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2DLC-X nrPDB 806 0.0 4Q93-A nrPDB 396 e-110 2CYB-A nrPDB 235 2e-62 2CYA-A nrPDB 178 4e-45 5NSF-B nrPDB 176 1e-44 2CYC-A nrPDB 151 6e-37 3VGJ-A nrPDB 124 1e-28 3P0I-A nrPDB 112 2e-25 2J5B-A nrPDB 74 1e-13 3FOC-A nrPDB 63 2e-10 6BQZ-A nrPDB 56 2e-08 1H3F-A nrPDB 56 3e-08 3JXE-A nrPDB 55 4e-08 5UJI-A nrPDB 52 5e-07 1R6T-A nrPDB 52 7e-07 3I05-A nrPDB 44 1e-04 3KT6-A nrPDB 43 2e-04 6BYQ-A nrPDB 42 4e-04 3TZE-A nrPDB 42 4e-04 3PRH-A nrPDB 41 8e-04 2EL7-A nrPDB 39 0.004 1YID-B nrPDB 35 0.039 3HV0-A nrPDB 35 0.050 3SZ3-A nrPDB 33 0.22 3N9I-A nrPDB 33 0.26 3A04-A nrPDB 32 0.32 4J75-A nrPDB 30 1.7 6EAC-A nrPDB 30 1.9 6MTK-A nrPDB 30 2.3 5V0I-A nrPDB 30 2.3 5E5H-A nrPDB 30 2.3 4ZCF-C nrPDB 30 2.6 5VBU-A nrPDB 29 2.9 5UR2-A nrPDB 29 4.4 5AC2-A nrPDB 28 5.2 3LFJ-A nrPDB 28 5.8 6DFU-A nrPDB 28 6.1 3FPI-A nrPDB 28 6.7 5DBX-A nrPDB 28 7.0 5AC0-A nrPDB 28 7.8 2G5H-A nrPDB 28 8.1 >2DLC-X nrPDB Length = 394 Score = 806 bits (2083), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/394 (100%), Positives = 394/394 (100%) Query: 1 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM 60 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM Sbjct: 1 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM 60 Query: 61 TKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLK 120 TKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLK Sbjct: 61 TKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLK 120 Query: 121 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF 180 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF Sbjct: 121 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF 180 Query: 181 LDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 LDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL Sbjct: 181 LDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 Query: 241 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI 300 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI Sbjct: 241 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI 300 Query: 301 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATP 360 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATP Sbjct: 301 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATP 360 Query: 361 QKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL 394 QKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL Sbjct: 361 QKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL 394 >4Q93-A nrPDB Length = 372 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 200/354 (56%), Positives = 267/354 (75%), Gaps = 12/354 (3%) Query: 9 PNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLK 68 P E LIT+NLQEVL + +K++L ++R LK+YWGTA TG+PH YFVPM+K+ADFLK Sbjct: 7 PEEKLHLITRNLQEVLGEEKLKEIL--KERELKIYWGTATTGKPHVAYFVPMSKIADFLK 64 Query: 69 AGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQ 128 AGCEVT+L ADLHA+LDNMKAP E++ R YYE IKA+L SI VP+EKLKF+ G+ YQ Sbjct: 65 AGCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQ 124 Query: 129 LTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFG 188 L+ +YT+D++RLS++V+Q+D+K+AGA+VVKQV +PLLSGL+YP +QALDE++L VD QFG Sbjct: 125 LSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFG 184 Query: 189 GVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKK 248 G+DQRKIF AE+ LP+LGY KR HLMNPMVPGL G KMS+S+ SKIDLL+ + VKK Sbjct: 185 GIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLT-GSKMSSSEEESKIDLLDRKEDVKK 243 Query: 249 KINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEM 308 K+ AFC PGNVE NG+LSF+++V+ P++ EF I R EK+GG TY ++ ++ Sbjct: 244 KLKKAFCEPGNVENNGVLSFIKHVLFPLKS--------EFVILRDEKWGGNKTYTAYVDL 295 Query: 309 KLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQK 362 + F E + P DLK V A+N+LL+PIR++F N ++ + YP + QK Sbjct: 296 EKDFAAEVVHPGDLKNSVEVALNKLLDPIREKF-NTPALKKLASAAYPDPSKQK 348 >2CYB-A nrPDB Length = 323 Score = 235 bits (600), Expect = 2e-62, Method: Compositional matrix adjust. Identities = 134/336 (39%), Positives = 201/336 (59%), Gaps = 16/336 (4%) Query: 7 VDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADF 66 +D E LIT+N +EV+ + ++ ++E +++ + Y G P+G H G+ + + KL D Sbjct: 1 MDITEKLRLITRNAEEVVTEEELRQLIETKEKP-RAYVGYEPSGEIHLGHMMTVQKLMDL 59 Query: 67 LKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSS 126 +AG E+ VLLAD+HA+L N K E + A Y K + ++ + + KFV+GS Sbjct: 60 QEAGFEIIVLLADIHAYL-NEKGTFEEIAEVADYN----KKVFIALGLDESRAKFVLGSE 114 Query: 127 YQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQ 186 YQL+ DY +D+ +++ I + N A+R+ +V ++ +P++S +IYPLMQALD L VD Sbjct: 115 YQLSRDYVLDVLKMARITTLNRARRSMDEVSRRKEDPMVSQMIYPLMQALDIAHLGVDLA 174 Query: 187 FGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQV 246 GG+DQRKI +LA ENLP LGY L P++ GL G KMS+S N I + + P++V Sbjct: 175 VGGIDQRKIHMLARENLPRLGYSSPVCLHTPILVGL-DGQKMSSSKGNY-ISVRDPPEEV 232 Query: 247 KKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFE 306 ++KI A+C G VEEN +L +Y I P +FG + ++R KFGG + Y SFE Sbjct: 233 ERKIRKAYCPAGVVEENPILDIAKYHILP----RFG----KIVVERDAKFGGDVEYASFE 284 Query: 307 EMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFA 342 E+ FK +L P DLKI VA +N LLE R+ Sbjct: 285 ELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARKRLG 320 >2CYA-A nrPDB Length = 364 Score = 178 bits (451), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 107/365 (29%), Positives = 185/365 (50%), Gaps = 31/365 (8%) Query: 7 VDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADF 66 VD E F I +N E++ + +K +L R +K Y G P+G H G+ V M K+ D Sbjct: 4 VDVEERFNRIARNTVEIVTEEELKGLLASGAR-IKGYIGYEPSGVAHIGWLVWMYKVKDL 62 Query: 67 LKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGS 125 ++AG + +VL A HA++ D + ++++ A+ ++ ++ + VP+E+++FV Sbjct: 63 VEAGVDFSVLEATWHAYINDKLGGDMDLIRAAAR----IVRRVMEAAGVPVERVRFVDAE 118 Query: 126 SYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQV--ANPLLSGLIYPLMQALDEQFLDV 183 DY + R++ S +RA + ++ A S LIYPLMQ D ++D+ Sbjct: 119 ELASDKDYWGLVIRVAKRASLARVRRALTIMGRRAEEAEVDASKLIYPLMQVSDIFYMDL 178 Query: 184 DCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG----------------K 227 D GG+DQRK +LA + LG KK + P++ L G K Sbjct: 179 DIALGGMDQRKAHMLARDVAEKLGRKKPVAIHTPIISSLQGPGRMEASQGEIDDVLAEVK 238 Query: 228 MSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFE 287 MS S P + + +++ +++KI A+C V+ N +L +Y++ F + F Sbjct: 239 MSKSKPETAVFVVDSDDDIRRKIRKAYCPAKQVQGNPVLEIARYIL-------FARDGFT 291 Query: 288 FFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEF 347 +DRP K+GGP+ Y S+EE++ + + +L P DLK VA+++ E++ PIR + Sbjct: 292 LRVDRPAKYGGPVEYTSYEELERDYTDGRLHPLDLKNAVAESLIEVVRPIRGAVLGDPAM 351 Query: 348 QEASE 352 + A E Sbjct: 352 KRALE 356 >5NSF-B nrPDB Length = 318 Score = 176 bits (447), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 107/331 (32%), Positives = 186/331 (56%), Gaps = 26/331 (7%) Query: 11 EAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAG 70 + F +I +N E+++ + +++VL+ ++ + G P+G+ H G+++ + K+ D AG Sbjct: 14 DEFEMIKRNTSEIISEEELREVLKKDEKSAGI--GFEPSGKIHLGHYLQIKKMIDLQNAG 71 Query: 71 CEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLT 130 ++ + LADL A+L N K L+ + Y K + ++ + K K+V GS + L Sbjct: 72 FDIIIWLADLGAYL-NQKGELDEIRKIGDYN----KKVFEAMGL---KAKYVYGSEHNLD 123 Query: 131 PDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGV 190 DYT++++RL+ + A+R+ + ++ NP ++ +IYP+MQ + VD GG+ Sbjct: 124 KDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNAIHYNGVDVAVGGM 183 Query: 191 DQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKI 250 +QRKI +LA E LP KK + NP++ GL GKMS+S N I + + P++++ KI Sbjct: 184 EQRKIHMLARELLP----KKVVCIHNPVLTGLDGEGKMSSSKGNF-IAVDDSPEEIRAKI 238 Query: 251 NSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKL 310 A+C G VE N ++ +Y + + I RPEKFGG +T S+EE++ Sbjct: 239 KKAYCPAGVVEGNPIMEIAKYFL-----------EYPLTIKRPEKFGGDLTVNSYEELES 287 Query: 311 AFKEEKLSPPDLKIGVADAINELLEPIRQEF 341 FK ++L P LK VA+ + ++LEPIR+ Sbjct: 288 LFKNKELHPMRLKNAVAEELIKILEPIRKRL 318 >2CYC-A nrPDB Length = 375 Score = 151 bits (381), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 114/371 (30%), Positives = 183/371 (49%), Gaps = 39/371 (10%) Query: 7 VDPNEAFGLITKN-LQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGY-FVPMTKLA 64 +D E L+ K +EVL + ++ + E+ L+ Y G +G H G + K+A Sbjct: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEIGAP-LQHYIGFEISGYIHLGTGLMAGAKIA 59 Query: 65 DFLKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRA-KYYELTIKAILRSINVPIEKLKFV 122 DF KAG + V LAD H+++ D + LEV+ A KY+++ ++ + + +K++FV Sbjct: 60 DFQKAGIKTRVFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFV 119 Query: 123 VGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPLMQALDEQFL 181 + S DY + +S V+ + R+ + +Q+ + + LIYP+MQ D + Sbjct: 120 LASEILEKGDYWQTVIDISKNVTLSRVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQ 179 Query: 182 DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAH---------LMNPMVPGLAQ-------- 224 V G+DQRK V+A E L Y H + + ++ GL + Sbjct: 180 GVTIAHAGMDQRKAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIES 239 Query: 225 ---------GGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAP 275 KMS S P S + + + P+++++K+ AFC V N +L +V+Y+I Sbjct: 240 EEEFKEIKAQMKMSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYII-- 297 Query: 276 IQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLE 335 F EF + RP KFGG +TY +FEE+K F E KL P DLK VA+ + LLE Sbjct: 298 -----FREEPTEFTVHRPAKFGGDVTYTTFEELKRDFAEGKLHPLDLKNAVAEYLINLLE 352 Query: 336 PIRQEFANNKE 346 PIR+ F + E Sbjct: 353 PIRRYFEKHPE 363 >3VGJ-A nrPDB Length = 373 Score = 124 bits (310), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 105/321 (32%), Positives = 159/321 (49%), Gaps = 27/321 (8%) Query: 37 KRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKA-GCEVTVLLADLHAFLDN-MKAPLEVV 94 KR L Y G P+GR H + + + + L + GC +AD A L+N M L+ + Sbjct: 54 KRKLICYDGFEPSGRMHIAQGLLKSIIVNKLTSNGCTFIFWIADWFAHLNNKMSGDLKKI 113 Query: 95 NYRAKYYELTIKAILRSINVPIEKLKFVVGSS-YQLTPD----YTMDIFRLSNIVSQNDA 149 Y+ + +S + +E ++F+ S P+ +DI R NI N Sbjct: 114 KKVGSYF----IEVWKSCGMNMENVQFLWASEEINKKPNEYWSLVLDISRSFNI---NRM 166 Query: 150 KRAGADVVKQVANP-LLSGLIYPLMQALDEQFLDVD-CQFGGVDQRKIFVLAEENLPSLG 207 KR + + S ++YP MQ D FL+VD CQ G +DQRK+ +LA E Sbjct: 167 KRCLKIMGRSEGEENYCSQILYPCMQCADIFFLNVDICQLG-IDQRKVNMLAREYCDIKK 225 Query: 208 YKKR-AHLMNPMVPGLAQGG-KMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGL 265 KK+ L + M+PGL +G KMS SD NS I + + V +KI A+C P +E N + Sbjct: 226 IKKKPVILSHGMLPGLLEGQEKMSKSDENSAIFMDDSESDVNRKIKKAYCPPNVIENNPI 285 Query: 266 LSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIG 325 ++ + +I P ++ EF + R EK GG TY + +E++ + + P DLK Sbjct: 286 YAYAKSIIFP--------SYNEFNLVRKEKNGGDKTYYTLQELEHDYVNGFIHPLDLKDN 337 Query: 326 VADAINELLEPIRQEFANNKE 346 VA IN+LL+P+R F NN E Sbjct: 338 VAMYINKLLQPVRDHFQNNIE 358 >3P0I-A nrPDB Length = 690 Score = 112 bits (281), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 104/365 (28%), Positives = 179/365 (49%), Gaps = 36/365 (9%) Query: 7 VDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHC--GYFVPMTKLA 64 ++ +E + L+ +E + +++++E +K ++ Y G P+GR H G F + Sbjct: 9 MNTDERYKLLRSVGEECIQESELRNLIE-KKPLIRCYDGFEPSGRMHIAQGIF-KAVNVN 66 Query: 65 DFLKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVV 123 AGCE +AD A + D + LE + +Y + + ++ + ++K+ F+ Sbjct: 67 KCTAAGCEFVFWVADWFALMNDKVGGELEKIRIVGRY----LIEVWKAAGMDMDKVLFL- 121 Query: 124 GSSYQLTPDYTMDIFRLSNIVSQNDAKRA--GADVVKQVANPLLSG-LIYPLMQALDEQF 180 SS ++T + +I QN R ++ + L + ++YPLMQ D F Sbjct: 122 WSSEEITSHADTYWRMVLDIGRQNTIARIKKCCTIMGKTEGTLTAAQVLYPLMQCCDIFF 181 Query: 181 LDVD-CQFGGVDQRKIFVLAEENLPSLGYK-KRAHLMNPMVPGLAQG-GKMSASDPNSKI 237 L D CQ G +DQRK+ +LA E +G K K L + M+ GL QG KMS SDP+S I Sbjct: 182 LKADICQLG-LDQRKVNMLAREYCDLIGRKLKPVILSHHMLAGLKQGQAKMSKSDPDSAI 240 Query: 238 DLLEEPKQVKKKINSAFC-----SPGNVEENGLLSFVQYVIAPI--QELKFGTNHFEFFI 290 + + + V +KI A+C S + ++G AP+ + ++F+ + Sbjct: 241 FMEDTEEDVARKIRQAYCPRVKQSASAITDDG---------APVATDDRNPVLDYFQCVV 291 Query: 291 -DRPEKFG--GPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEF 347 RP TY ++E+++ AF +++S LK + D +N LLEP+RQ FA+N+E Sbjct: 292 YARPGAAATIDGTTYATYEDLEQAFVSDEVSEDALKSCLIDEVNALLEPVRQHFASNEEA 351 Query: 348 QEASE 352 E E Sbjct: 352 HELLE 356 Score = 38.5 bits (88), Expect = 0.005, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 39/81 (48%), Gaps = 10/81 (12%) Query: 246 VKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSF 305 +++KI A+ +P N E N ++S Q+++A H I+R E GG ++Y + Sbjct: 583 IRRKIKKAYSAP-NEEANPVISVAQHLLA---------QHGALSIERGEANGGNVSYNTP 632 Query: 306 EEMKLAFKEEKLSPPDLKIGV 326 E + L P DLK V Sbjct: 633 EALVADCGSGALHPADLKAAV 653 >2J5B-A nrPDB Length = 348 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 77/334 (23%), Positives = 153/334 (45%), Gaps = 43/334 (12%) Query: 38 RHLKLYWGTAPTGRPHCGY-FVPMTKLADFLKAGCEVTVLLADLHAFLD-NMKAPLEVVN 95 R Y G P+GR H + + + ++ G ++ + +AD A ++ M + + Sbjct: 39 RIFTAYNGFEPSGRIHIAQALITVMNTNNMIECGGQMIIYIADWFAKMNLKMNGDINKIR 98 Query: 96 YRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLT-PDYTMDIFRLSNIVSQNDAKRAGA 154 +Y+ + ++ + ++ +F+ S + + P Y + ++ + + KR Sbjct: 99 ELGRYF----IEVFKACGINLDGTRFIWASEFIASNPSYIERMLDIAEFSTISRVKRCCQ 154 Query: 155 DVVKQVANPL-LSGLIYPLMQALDE-----QFLDVDCQFGGVDQRKIFVLAEENLPSLGY 208 + + ++ L S + YP MQA D + +D+ CQ G +DQRK+ +LA E G Sbjct: 155 IMGRNESDCLKASQIFYPCMQAADVFELVPEGIDI-CQLG-IDQRKVNMLAIEYANDRGL 212 Query: 209 KKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLS 267 K L + M+ L+ KMS SDP I + + ++V +KI+ A+C+ +N + Sbjct: 213 KIPISLSHHMLMSLSGPKKKMSKSDPQGAIFMDDTEQEVSEKISRAYCTDETF-DNPIFE 271 Query: 268 FVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVA 327 +++Y++ FGT + G I Y E ++ F ++ +LK VA Sbjct: 272 YIKYLLLRW----FGTLN----------LCGKI-YTDIESIQEDFS--SMNKRELKTDVA 314 Query: 328 DAINELLEPIRQEF---------ANNKEFQEASE 352 + IN +++ +R+ F +N K +Q+ S+ Sbjct: 315 NYINTIIDLVREHFKKPELSELLSNVKSYQQPSK 348 >3FOC-A nrPDB Length = 451 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 35/76 (46%), Positives = 46/76 (60%), Gaps = 2/76 (2%) Query: 189 GVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGL-AQGGKMSASDPNSKIDLLEEPKQVK 247 G++Q F LA + P +G+ K A+L+ +PGL G KMSASDPNS I L + P Q+K Sbjct: 294 GIEQDPYFRLARDLAPRMGHPKNAYLLGKFLPGLQGSGTKMSASDPNSAIYLTDTPAQIK 353 Query: 248 KKINS-AFCSPGNVEE 262 KIN AF + EE Sbjct: 354 NKINRYAFSGGRDTEE 369 >6BQZ-A nrPDB Length = 408 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 76/292 (26%), Positives = 128/292 (43%), Gaps = 32/292 (10%) Query: 11 EAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTG-RPHCGYFVPMTKLADFLKA 69 E LI + E+++ + + L+ + R LK+ G PT H G+ V + KL F Sbjct: 13 EQLALIQRGTHEIISEEDLLKKLK-ENRPLKIKAGFDPTAPDLHLGHTVLINKLKTFQDL 71 Query: 70 GCEVTVLLADLHAFLDN------MKAPL--EVVNYRAKYYELTIKAILRSINVPIEKLKF 121 G EVT L+ D A + + + PL E V AK Y+ + + + ++ K++F Sbjct: 72 GHEVTFLIGDYTAMIGDPTGKSATRPPLSREQVEANAKTYQ---EQVFKILDPNKTKVRF 128 Query: 122 VVGSSYQLTPDYTMDIFRLSNIVSQNDAKRA--GADVVKQVAN--PL-LSGLIYPLMQAL 176 +S D+ +L+ SQ R D K+ N P+ + +YPL+Q Sbjct: 129 ---NSEWFNQKSAADLIQLA---SQQTVSRMLERDDFTKRYNNHQPIAIHEFLYPLVQGY 182 Query: 177 DEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSK 236 D L+ D + GG DQ ++ G + + + P++ GL KMS S N Sbjct: 183 DSIALEADVELGGTDQTFNLLMGRTLQSRYGQESQVCITVPILEGLDGVNKMSKSLGNY- 241 Query: 237 IDLLEEPKQVKKKINSAFCSPGNVEEN--GLLSF--VQYVIAPIQELKFGTN 284 I + + P + +K+ P ++ E LLSF + + A + E+ G N Sbjct: 242 IGVFDAPGAMYQKV---LSMPDSLIERYFDLLSFKSLDEIKALLDEIAAGRN 290 >1H3F-A nrPDB Length = 432 Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 66/258 (25%), Positives = 115/258 (44%), Gaps = 27/258 (10%) Query: 9 PNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRP--HCGYFVPMTKLADF 66 P EA L+ + +E++ + + L+ + R L + G PT RP H G+ V + K+ F Sbjct: 8 PEEALALLKRGAEEIVPEEELLAKLK-EGRPLTVKLGADPT-RPDLHLGHAVVLRKMRQF 65 Query: 67 LKAGCEVTVLLADLHAFLDN------MKAPLEVVNYR--AKYYELTIKAILRSINVPIE- 117 + G +V +++ D + + + PL + R AK Y ILR E Sbjct: 66 QELGHKVVLIIGDFTGMIGDPSGRSKTRPPLTLEETRENAKTYVAQAGKILRQEPHLFEL 125 Query: 118 --KLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKR---AGADVVKQVANPLLSGLIYPL 172 +++ G +++ T + ++ ++ + D K+ AG + L L+YP Sbjct: 126 RYNSEWLEGLTFKEVVRLT-SLMTVAQMLEREDFKKRYEAGIPIS-------LHELLYPF 177 Query: 173 MQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASD 232 QA D + D + GG DQR ++ E + G + + P++ GL KMS S Sbjct: 178 AQAYDSVAIRADVEMGGTDQRFNLLVGREVQRAYGQSPQVCFLMPLLVGLDGREKMSKSL 237 Query: 233 PNSKIDLLEEPKQVKKKI 250 N I L E P+ + KK+ Sbjct: 238 DNY-IGLTEPPEAMFKKL 254 >3JXE-A nrPDB Length = 392 Score = 55.5 bits (132), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 66/227 (29%), Positives = 95/227 (41%), Gaps = 18/227 (7%) Query: 28 IIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM--TKLADFLKAGCEVTVLLADLHAFLD 85 I+KD E R LY G P+G H G+ +P TK K G + + + D FL Sbjct: 64 ILKDYEE--GRGFFLYTGRGPSGPMHIGHIIPFFATKWLQ-EKFGVNLYIQITDDEKFL- 119 Query: 86 NMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVS 145 K L + + Y+ IL I V + K + + + T Y M I I Sbjct: 120 -FKENLTFDDTKRWAYD----NILDIIAVGFDPDKTFIFQNSEFTKIYEMAI----PIAK 170 Query: 146 QNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQF-GGVDQRKIFVLAEENLP 204 + + A A V + + +P +Q F C +DQ + L + Sbjct: 171 KINFSMAKA-VFGFTEQSKIGMIFFPAIQIAPTFFERKRCLIPAAIDQDPYWRLQRDFAE 229 Query: 205 SLGYKKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVKKKI 250 SLGY K A L + VP L GKMSAS P + I L + P+ V+KK+ Sbjct: 230 SLGYYKTAALHSKFVPSLTSLSGKMSASKPETAIYLTDSPEDVEKKV 276 >5UJI-A nrPDB Length = 388 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 35/87 (40%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Query: 182 DVDCQF-GGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG--KMSASDPNSKID 238 D+ C +DQ F + + P +GY K A L + P L QG KMSASDPNS I Sbjct: 206 DIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPAL-QGAQTKMSASDPNSSIF 264 Query: 239 LLEEPKQVKKKINSAFCSPG--NVEEN 263 L + KQ+K K+N S G +EE+ Sbjct: 265 LTDTAKQIKTKVNKHAFSGGRDTIEEH 291 >1R6T-A nrPDB Length = 477 Score = 51.6 bits (122), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 35/87 (40%), Positives = 46/87 (52%), Gaps = 6/87 (6%) Query: 182 DVDCQF-GGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG--KMSASDPNSKID 238 D+ C +DQ F + + P +GY K A L + P L QG KMSASDPNS I Sbjct: 302 DIQCLIPCAIDQDPYFRMTRDVAPRIGYPKPALLHSTFFPAL-QGAQTKMSASDPNSSIF 360 Query: 239 LLEEPKQVKKKINSAFCSPG--NVEEN 263 L + KQ+K K+N S G +EE+ Sbjct: 361 LTDTAKQIKTKVNKHAFSGGRDTIEEH 387 >3I05-A nrPDB Length = 395 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 36/96 (37%), Positives = 47/96 (48%), Gaps = 4/96 (4%) Query: 189 GVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVK 247 +DQ F L + P LGY K A + + PGL+ GKMS+S + + L + K VK Sbjct: 231 AIDQDPYFRLTRDIAPRLGYLKPAVIHSKFFPGLSGPKGKMSSSS-GTAVLLTDTEKMVK 289 Query: 248 KKINSAFCSPGNV--EENGLLSFVQYVIAPIQELKF 281 KIN S G +E+ LL V PIQ L F Sbjct: 290 DKINKHAFSGGGATKQEHFLLGANVEVDVPIQWLSF 325 >3KT6-A nrPDB Length = 438 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 29/77 (37%), Positives = 39/77 (50%), Gaps = 3/77 (3%) Query: 189 GVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG--KMSASDPNSKIDLLEEPKQV 246 +DQ F + + L Y K A L + P L QG KMSASD + I + + PKQ+ Sbjct: 256 AIDQDPYFRVCRDVADKLKYSKPALLHSRFFPAL-QGSTTKMSASDDTTAIFMTDTPKQI 314 Query: 247 KKKINSAFCSPGNVEEN 263 +KKIN S G V + Sbjct: 315 QKKINKYAFSGGQVSAD 331 >6BYQ-A nrPDB Length = 410 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 59/224 (26%), Positives = 97/224 (43%), Gaps = 30/224 (13%) Query: 46 TAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFL------DNMKAPL--EVVNYR 97 TAP H G+ V + KLA + G V L+ D A + + + PL E V Sbjct: 56 TAPD--LHLGHTVLIQKLALLQQYGARVKFLIGDFTAMIGDPTGKNETRKPLNREQVLEN 113 Query: 98 AKYYELTIKAILRSINVPIEKLKFVVGSSY--QLTPDYTMDI---FRLSNIVSQND-AKR 151 AK YE I IL + + S++ L +++ F ++ ++ ++D AKR Sbjct: 114 AKTYEEQIYKILDQKHTEV-----CFNSTWLDALGAKGMIELCAKFSVARMLERDDFAKR 168 Query: 152 AGADVVKQVANPL-LSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKK 210 + P+ + +YPL+Q D + D + GG DQ+ ++ + G K Sbjct: 169 HKEN------RPISIVEFLYPLLQGYDSVAMGADIELGGNDQKFNLLVGRFLQRAYGLNK 222 Query: 211 RAHLMN-PMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSA 253 ++ P++ GL KMS S N + + EEP + KI S Sbjct: 223 EQSIITMPLLEGLDGVQKMSKSLGNY-VGITEEPNAMFGKIMSV 265 >3TZE-A nrPDB Length = 406 Score = 42.0 bits (97), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 28/72 (38%), Positives = 38/72 (52%), Gaps = 1/72 (1%) Query: 188 GGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGL-AQGGKMSASDPNSKIDLLEEPKQV 246 VDQ F LA + +LG KK + + ++P L KMSASDPNS I L + + Sbjct: 249 AAVDQDPFFRLARDKAKALGEKKPSSIYVSLLPDLKGVNRKMSASDPNSSIYLDDAQDTI 308 Query: 247 KKKINSAFCSPG 258 +KKI + S G Sbjct: 309 RKKIIAYAYSGG 320 >3PRH-A nrPDB Length = 388 Score = 41.2 bits (95), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 38/113 (33%), Positives = 54/113 (47%), Gaps = 29/113 (25%) Query: 164 LLSGLI-YPLMQALDEQFLDVDCQFGGVDQRK------------------IFVLAEENLP 204 ++SGL+ YP + A D D G DQ++ IF + E +P Sbjct: 152 VVSGLLTYPPLMAADILLYGTDLVPPGEDQKQHLELTRNLAERFNKKYNDIFTIPEVKIP 211 Query: 205 SLGYKKRAHLMNPMVPGLAQGGKMSASDPNSK--IDLLEEPKQVKKKINSAFC 255 +G + + L +P+ KMS SDPN K I LL+EPKQ++KKI SA Sbjct: 212 KVGARIMS-LNDPL-------KKMSKSDPNQKAYITLLDEPKQLEKKIKSAVT 256 >2EL7-A nrPDB Length = 337 Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust. Identities = 61/250 (24%), Positives = 97/250 (38%), Gaps = 33/250 (13%) Query: 45 GTAPTGRPHCGYFVPMTK--LADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYE 102 G P+G H G ++ K +A K G + + D HA + + + R Sbjct: 7 GIQPSGEIHIGNYLGAIKQWVAIGEKLGRDAFFCIVDYHALTNPLAYDPSTLAQR----- 61 Query: 103 LTIKAILRSINVPI--EKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGA--DVVK 158 T +A L +I + EK+ V S P++T + + + D R D Sbjct: 62 -TFEAALVNIAAGLDPEKVTLFVQSH---VPEHTELSWVFTTLTPLGDLTRMTQFKDKAS 117 Query: 159 QVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEE------NLPSLGYKKRA 212 + L+YP++QA D D G DQ + L E +L + + Sbjct: 118 KQETVWSGLLMYPVLQAADILIYKADTVPVGEDQVQHIELTREIARRFNHLFGETFPEPQ 177 Query: 213 HLMN---PMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINS--------AFCSPGNVE 261 L+N P VPG+ KMS S N+ I LLE + + +KI PG+ E Sbjct: 178 ALLNPEAPRVPGIDGKAKMSKSLGNT-IGLLEPEESIWQKIQHLPDDPQRIRLSDPGDPE 236 Query: 262 ENGLLSFVQY 271 L +++ Y Sbjct: 237 RTILFTYLSY 246 >1YID-B nrPDB Length = 351 Score = 35.4 bits (80), Expect = 0.039, Method: Compositional matrix adjust. Identities = 57/243 (23%), Positives = 93/243 (38%), Gaps = 24/243 (9%) Query: 45 GTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELT 104 G PTG H G+ + L+ E+ VLLAD+ A D+ P +V + L Sbjct: 28 GDRPTGALHLGHLAGSLQNRVRLQDEAELFVLLADVQALTDHFDRPEQV-----RENVLA 82 Query: 105 IKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVV-KQVANP 163 + + + +K VV S+ + T+ L + A++ K Sbjct: 83 VALDYLAAGLDPQKTTCVVQSAVPELAELTVYFLNLVTVSHLRQNPTVKAEIAQKGYGER 142 Query: 164 LLSG-LIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENL--------PSLGYKKRAHL 214 + +G +YP+ QA D G DQ + E + P L + Sbjct: 143 VPAGFFVYPVSQAADIAAFGATLVPVGDDQLPMLEQTREIVRRFNALYAPVLAEPQAQLS 202 Query: 215 MNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGN--------VEENGLL 266 P +PGL KMS S N+ I L + +V +K+ + PG+ VE N + Sbjct: 203 RVPRLPGLDGQAKMSKSLGNA-IALGDSADEVARKVMGMYTDPGHLRASDPGRVEGNPVF 261 Query: 267 SFV 269 +F+ Sbjct: 262 TFL 264 >3HV0-A nrPDB Length = 393 Score = 35.0 bits (79), Expect = 0.050, Method: Compositional matrix adjust. Identities = 64/238 (26%), Positives = 97/238 (40%), Gaps = 30/238 (12%) Query: 42 LYWGTAPTGRP-HCGYFVPM--TK-LADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYR 97 LY G P+ H G+ VP TK L D K + + L D F+ LE + Sbjct: 77 LYTGRGPSSESLHVGHLVPFLFTKYLQDTFKV--PLVIQLTDDEKFIFKSNLTLEETHNY 134 Query: 98 AKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVV 157 A YE +K I+ P +L F+ ++ + + DI R+ +S + K Sbjct: 135 A--YE-NMKDIIACGFDP--ELTFIF-TNLEYIAELYPDILRIEKKISCSQIKSIFG--F 186 Query: 158 KQVANPLLSGLIYPLMQA---LDEQF-------LDVDCQF-GGVDQRKIFVLAEENLPSL 206 K N + +P +QA F D+ C +DQ F + + P L Sbjct: 187 KDSCN--VGKFAFPAVQAAPAFSSSFPHIFGGRTDIHCLVPHAIDQDPYFRMVRDVAPRL 244 Query: 207 GYKKRAHLMNPMVPGLAQGG--KMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEE 262 GY K + + + +P L QG KMSAS NS I + + + ++ KI S G E Sbjct: 245 GYLKPSSIHSIFLPSL-QGSQTKMSASVQNSSIFVNDNEESIRNKIMKYAFSGGQATE 301 >3SZ3-A nrPDB Length = 341 Score = 33.1 bits (74), Expect = 0.22, Method: Compositional matrix adjust. Identities = 37/126 (29%), Positives = 55/126 (43%), Gaps = 23/126 (18%) Query: 227 KMSASDPNSK--IDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTN 284 KMS SD N K I LLE+PK + KKIN A IA E K G Sbjct: 201 KMSKSDDNRKNVITLLEDPKSIIKKINKAQTDAETPPR----------IAYDVENKAGIA 250 Query: 285 HFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFA-- 342 + T K+F E++ + ++ P K V +A+ +LEP++ E+ Sbjct: 251 NLMGLY-------SAATGKTFAEIEAQYAGVEMYGP-FKKDVGEAVVAMLEPVQAEYQRI 302 Query: 343 -NNKEF 347 N++E+ Sbjct: 303 RNDREY 308 >3N9I-A nrPDB Length = 346 Score = 32.7 bits (73), Expect = 0.26, Method: Compositional matrix adjust. Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 21/122 (17%) Query: 227 KMSASDPNSK--IDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTN 284 KMS SD N I+LLE+PK V KKI A + +E L ++Y + E K G + Sbjct: 207 KMSKSDDNRNNVIELLEDPKSVVKKIKRAMT---DSDEPAL---IRYDV----EKKAGVS 256 Query: 285 HFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANN 344 + + +T +S E++ F + LK VADA++ +L +++ + Sbjct: 257 NLLDIL-------SGVTGQSIPELEAQFTGQMYG--HLKGAVADAVSGMLSELQERYRTY 307 Query: 345 KE 346 +E Sbjct: 308 RE 309 >3A04-A nrPDB Length = 372 Score = 32.3 bits (72), Expect = 0.32, Method: Compositional matrix adjust. Identities = 58/238 (24%), Positives = 102/238 (42%), Gaps = 30/238 (12%) Query: 32 VLEVQKR--HLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKA 89 +LE + R + + G P+G+ H G+ + + +L K G +V V +AD AF Sbjct: 61 ILEAKARGERVAVLTGFMPSGKFHFGHKLTVDQLIYLQKNGFKVFVAIADAEAFAVRRIG 120 Query: 90 PLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDA 149 E V + Y A + ++ + + +F ++ + TP FRL + S Sbjct: 121 REEAVRIAVEEY----IANMIALGLDPKDTEFYFQTN-RGTP-----YFRLIQLFS---G 167 Query: 150 KRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFG---------GVDQ----RKIF 196 K A++ + ++ L QA D + +D ++G G DQ R Sbjct: 168 KVTAAEMEAIYGELTPAKMMASLTQAADILHVQLD-EYGGYRHVVVPVGADQDPHLRLTR 226 Query: 197 VLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAF 254 LA+ + ++ A + + PGL G KMS+S P+S I L + P+ + K+ A Sbjct: 227 DLADRMAGVVELERPASTYHKLQPGL-DGRKMSSSRPDSTIFLTDPPEVARNKLFRAL 283 >4J75-A nrPDB Length = 409 Score = 30.0 bits (66), Expect = 1.7, Method: Compositional matrix adjust. Identities = 57/249 (22%), Positives = 100/249 (40%), Gaps = 35/249 (14%) Query: 36 QKRHLKLYWGTAPTGRP-HCGYFVPMTKLADFLKAGCEV--TVLLADLHAFLDNMKAPLE 92 Q + +Y G P+ H G+ +P +L+ V + L+D +L N LE Sbjct: 76 QHKCFYIYTGRGPSSLSMHLGHLIPFY-FCKYLQEAFNVPLVIQLSDDEKYLFNQNYSLE 134 Query: 93 VVNYRAKYYELTIKAILRSINVPIE-KLKFVVGSSYQLTPDY--TMDIFRLSNI-VSQND 148 +N LT + + I+V + +L F+ ++ Y + I + + + S N Sbjct: 135 YIN------TLTNENVKDIISVGLNPELTFIFKNTEYAGYLYPTVLSIHKKTTLNQSMNV 188 Query: 149 AKRAGADVVKQVANPLLSGLIYPLMQALDEQFL--DVDCQF-GGVDQRKIFVLAEENLPS 205 +D + +++ P S I P FL ++ C G+DQ F L+ + Sbjct: 189 FGFNHSDNIGKISYP--SFQIAPCFSQCFPNFLGKNIPCLVPQGIDQDPYFRLSRDIAVK 246 Query: 206 LGYKKRAHLMNPMVPGLA--------------QGGKMSAS--DPNSKIDLLEEPKQVKKK 249 + K + + +PGL GK +++ NS I L + P+Q+K K Sbjct: 247 MALHKPVVVHSVFMPGLQGVNSKMSSTKKKKDDNGKSNSTFDHNNSVIFLTDTPEQIKNK 306 Query: 250 INSAFCSPG 258 IN S G Sbjct: 307 INKYAFSGG 315 >6EAC-A nrPDB Length = 488 Score = 30.0 bits (66), Expect = 1.9, Method: Compositional matrix adjust. Identities = 28/120 (23%), Positives = 53/120 (44%), Gaps = 18/120 (15%) Query: 114 VPIEKLKFVVGSSYQLTPDYTMDIFR--LSNIVSQNDAKRAGADVVKQVANPLLSGLIYP 171 V +E L+ +G L + +D+ R L V+Q+ + + +++ + N SG+ Y Sbjct: 312 VSVEALRETIGLFLPLYQAHYLDLMRRRLGLTVAQDQDDKLVSQLLQLMQN---SGVDYT 368 Query: 172 L-------------MQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPM 218 L ++AL + F+D+ + + AEEN K+R H +NP+ Sbjct: 369 LFFRRLGDQPAAQALRALRDDFVDIKVFDDWAQAYQARIAAEENGTEQARKERMHAVNPL 428 >6MTK-A nrPDB Length = 329 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 58/238 (24%), Positives = 94/238 (39%), Gaps = 28/238 (11%) Query: 40 LKLYWGTAPTGRPHCGYF----VPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVN 95 +++ G TG PH G +P +LA K + +A+LH L +K + Sbjct: 9 MRILTGIQATGTPHLGNLLGAIIPAIELAK--KPENDSLFFIANLHT-LTQIK---DAAQ 62 Query: 96 YRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYT--MDIFRLSNIVSQNDAKRAG 153 R YE I A + + EK F S T + T +D F ++ + + Sbjct: 63 LRQNTYE--IAAAWLACGLDTEKTIFYRQSDIPETCELTWYLDCFFPFQRLTLAHSFKDK 120 Query: 154 ADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAH 213 AD ++ V L + YP++ A D D + G DQ + + + + Sbjct: 121 ADRLQDVNAGLFN---YPILMAADILLYDAEVVPVGKDQLQHLEITRDVAEKFNRQMGEV 177 Query: 214 LMNP---------MVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEE 262 + P VPG G KMS S N I++ K++KK+I S ++EE Sbjct: 178 FVLPGAEIQESTKYVPG-TDGHKMSKSRGNI-INIFLPEKELKKQIMSIESDSKSLEE 233 >5V0I-A nrPDB Length = 337 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 49/179 (27%), Positives = 79/179 (44%), Gaps = 33/179 (18%) Query: 195 IFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSK--IDLLEEPKQVKKKINS 252 IF + E +P G A +M+ + P KMS SD N I LLE+PK V KKI Sbjct: 174 IFKVPEPFIPKSG----ARVMSLLEPT----KKMSKSDDNRNNVIGLLEDPKSVVKKIKR 225 Query: 253 AFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAF 312 A V ++ V+Y +Q +N + +T +S E++ F Sbjct: 226 A------VTDSDEPPVVRY---DVQNKAGVSNLLDIL--------SAVTGQSIPELEKQF 268 Query: 313 KEEKLSPPDLKIGVADAINELLEPIRQ---EFANNKEF-QEASEKGYPVATPQKSKKAK 367 + + LK VADA++ +L +++ F N++ F Q+ + G A+ S+ K Sbjct: 269 EGKMYG--HLKGEVADAVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLK 325 >5E5H-A nrPDB Length = 514 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 29/140 (20%), Positives = 65/140 (46%), Gaps = 27/140 (19%) Query: 118 KLKFVVGSSYQLTPDYT------MDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYP 171 +++ SS+ L+P+ MD FR I+ Q D + +++++ ++G+I Sbjct: 308 RMRIASASSFSLSPEAAEEINNRMDFFRSKIILRQQDVSNS-PGIIRRLGCIAMNGMI-- 364 Query: 172 LMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLG----YKKRAHLMNPMVPGLAQGGK 227 + D +G V+ + V+ + + +G + + ++L + P A+GGK Sbjct: 365 ----------EADI-YGNVNSTR--VMGSKMMNGIGGSGDFARSSYLSIFLSPSTAKGGK 411 Query: 228 MSASDP-NSKIDLLEEPKQV 246 +SA P + +D + + Q+ Sbjct: 412 ISAIVPMAAHVDHIMQDAQI 431 >4ZCF-C nrPDB Length = 970 Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust. Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 10/69 (14%) Query: 75 VLLADLHAFLDNMKAPLEVVNYRAKYY----------ELTIKAILRSINVPIEKLKFVVG 124 VL +DL DN KAPL+ + +Y + I++++ +P +K V Sbjct: 831 VLSSDLGVLQDNAKAPLDTYLFEEVFYDSELERRNITDREIQSVVVFSKIPKNSIKIPVA 890 Query: 125 SSYQLTPDY 133 Y +PD+ Sbjct: 891 GGYTYSPDF 899 >5VBU-A nrPDB Length = 476 Score = 29.3 bits (64), Expect = 2.9, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 37/80 (46%), Gaps = 18/80 (22%) Query: 289 FIDRPEKFGGPITYK---------SFEEMKLAFK-EEKLSPPDLKIGVADAINELLEPIR 338 F RPE P+TYK S + L +K +KL+ L +G+ D++ ++E + Sbjct: 70 FAGRPE----PLTYKLVSRNYPDLSLGDYSLLWKAHKKLTRSALLLGIRDSMEPVVEQLT 125 Query: 339 QEFANNKEFQEASEKGYPVA 358 QEF Q G PVA Sbjct: 126 QEFCERMRAQ----PGTPVA 141 >5UR2-A nrPDB Length = 984 Score = 28.9 bits (63), Expect = 4.4, Method: Compositional matrix adjust. Identities = 42/154 (27%), Positives = 62/154 (40%), Gaps = 33/154 (21%) Query: 27 QIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMT---------KLADFLKAGCEVTVLL 77 +I+ + E +K H L+ G+ P G G+F P T KLA G V V+ Sbjct: 830 RILGTIAEAEKNHKLLFKGSVPGG----GFFAPPTIFGDVPGDAKLAQAEIFGPVVAVIR 885 Query: 78 ADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRS-INVPIEKLKFVVGSSY-------QL 129 A N+ L++ N + Y LT RS N+ K + VG+ Y + Sbjct: 886 A------KNLDQALDIAN--STEYALTGGVFSRSPANINRVKEELEVGNLYVNRGITGAM 937 Query: 130 TPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANP 163 + F++S I S K G D +KQ P Sbjct: 938 VDRHPFGGFKMSGIGS----KTGGPDYLKQYMEP 967 >5AC2-A nrPDB Length = 501 Score = 28.5 bits (62), Expect = 5.2, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 25/50 (50%) Query: 210 KRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGN 259 K+ L NP+ PG+ QG ++ + +DL+E K+ K+ GN Sbjct: 328 KKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGN 377 >3LFJ-A nrPDB Length = 187 Score = 28.5 bits (62), Expect = 5.8, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 9/82 (10%) Query: 318 SPPDLKI---GVADAINELLEPIRQE------FANNKEFQEASEKGYPVATPQKSKKAKK 368 +PP +K+ GV A+ E + E F N + + G P+ T AK Sbjct: 72 APPGVKVKVFGVDAALKEWSQKTSVEEKVFLLFKNIDTCKRVMDGGLPITTLNIGGVAKT 131 Query: 369 PKNKGTKYPGATKTNEIATKLE 390 P+ KG + +E+ T LE Sbjct: 132 PQRKGISQSVSLSEDEVKTLLE 153 >6DFU-A nrPDB Length = 337 Score = 28.1 bits (61), Expect = 6.1, Method: Compositional matrix adjust. Identities = 16/29 (55%), Positives = 18/29 (62%), Gaps = 2/29 (6%) Query: 227 KMSASDPNSK--IDLLEEPKQVKKKINSA 253 KMS SD N + LLE+PK V KKI A Sbjct: 198 KMSKSDDNRNNVVTLLEDPKSVAKKIKRA 226 >3FPI-A nrPDB Length = 165 Score = 28.1 bits (61), Expect = 6.7, Method: Compositional matrix adjust. Identities = 22/72 (30%), Positives = 33/72 (45%), Gaps = 4/72 (5%) Query: 180 FLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDL 239 F D D F G D R + A + + GYK L N + +AQ KM+ P +++L Sbjct: 66 FPDTDPAFKGADSRGLLREAYRRILAKGYK----LGNLDITIIAQAPKMAPHIPQMRVNL 121 Query: 240 LEEPKQVKKKIN 251 E+ + IN Sbjct: 122 AEDLQCHMDDIN 133 >5DBX-A nrPDB Length = 328 Score = 28.1 bits (61), Expect = 7.0, Method: Compositional matrix adjust. Identities = 31/133 (23%), Positives = 52/133 (39%), Gaps = 28/133 (21%) Query: 272 VIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVAD--- 328 V+ ++ F + + F I E G Y + MK+ + PP L+ GV D Sbjct: 193 VMEQVRGYDFKADMWSFGITAIELATGAAPYHKYPPMKVLMLTLQNDPPTLETGVEDKEM 252 Query: 329 ------AINELL----------EPIRQEFANNKEFQEASEKGYPV-----ATPQKSKKAK 367 + +LL P E K FQ+A + Y + TP +++AK Sbjct: 253 MKKYGKSFRKLLSLCLQKDPSKRPTAAELLKCKFFQKAKNREYLIEKLLTRTPDIAQRAK 312 Query: 368 KPKNKGTKYPGAT 380 K + + PG++ Sbjct: 313 KVR----RVPGSS 321 >5AC0-A nrPDB Length = 501 Score = 28.1 bits (61), Expect = 7.8, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 25/50 (50%) Query: 210 KRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGN 259 K+ L NP+ PG++QG ++ +DL+E K+ K+ GN Sbjct: 328 KKYVLGNPLTPGVSQGPQIDKEQYEKILDLIESGKKEGAKLECGGGPWGN 377 >2G5H-A nrPDB Length = 485 Score = 27.7 bits (60), Expect = 8.1, Method: Compositional matrix adjust. Identities = 16/47 (34%), Positives = 25/47 (53%) Query: 300 ITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKE 346 I Y+S E + K++K+ P D+ + DAI E I+ A +KE Sbjct: 3 IRYESVENLLTLIKDKKIKPSDVVKDIYDAIEETDPTIKSFLALDKE 49 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2DLC-X nrPDB 549 e-157 2CYA-A nrPDB 389 e-109 2CYB-A nrPDB 387 e-108 4Q93-A nrPDB 387 e-108 2CYC-A nrPDB 364 e-101 3VGJ-A nrPDB 349 9e-97 5NSF-B nrPDB 342 1e-94 3P0I-A nrPDB 340 7e-94 2J5B-A nrPDB 304 5e-83 6BQZ-A nrPDB 230 1e-60 1H3F-A nrPDB 215 3e-56 3JXE-A nrPDB 188 4e-48 6BYQ-A nrPDB 183 8e-47 5UJI-A nrPDB 164 6e-41 1R6T-A nrPDB 163 2e-40 3I05-A nrPDB 149 1e-36 3KT6-A nrPDB 144 6e-35 3TZE-A nrPDB 140 9e-34 3FOC-A nrPDB 133 2e-31 3PRH-A nrPDB 105 3e-23 Sequences not found previously or not previously below threshold: 3HV0-A nrPDB 153 1e-37 4J75-A nrPDB 125 3e-29 3A04-A nrPDB 119 3e-27 1YID-B nrPDB 109 2e-24 2EL7-A nrPDB 105 3e-23 2G36-A nrPDB 102 2e-22 6NCR-A nrPDB 102 3e-22 5V0I-A nrPDB 97 1e-20 5DK4-A nrPDB 94 8e-20 2YY5-A nrPDB 94 1e-19 6DFU-A nrPDB 93 2e-19 3SZ3-A nrPDB 93 3e-19 5EKD-A nrPDB 92 4e-19 3N9I-A nrPDB 91 6e-19 3TZL-A nrPDB 81 7e-16 6MTK-A nrPDB 76 2e-14 5IHX-A nrPDB 72 4e-13 2JAN-A nrPDB 72 5e-13 6HB6-A nrPDB 71 1e-12 1X8X-A nrPDB 71 1e-12 3TS1-A nrPDB 70 2e-12 5TEW-A nrPDB 69 2e-12 1JIJ-A nrPDB 69 3e-12 6N0W-A nrPDB 69 4e-12 4OUD-B nrPDB 68 6e-12 1TYB-E nrPDB 67 1e-11 3U1V-A nrPDB 67 1e-11 5IJX-A nrPDB 67 2e-11 6OTJ-A nrPDB 66 3e-11 2RKJ-A nrPDB 65 5e-11 2PID-A nrPDB 65 7e-11 3HZR-A nrPDB 64 1e-10 5KPG-A nrPDB 35 0.070 3TQO-A nrPDB 32 0.58 5JTA-A nrPDB 32 0.60 2HZ7-A nrPDB 31 0.78 4H3S-A nrPDB 31 0.80 1V33-A nrPDB 31 1.1 2PQ6-A nrPDB 31 1.5 5ZDO-A nrPDB 30 1.6 1IRX-A nrPDB 30 1.7 4ANW-A nrPDB 30 1.8 4L0O-H nrPDB 30 2.0 5K0S-A nrPDB 30 2.0 6A7J-A nrPDB 30 2.1 5L6W-C nrPDB 28 7.5 4GEW-A nrPDB 28 9.5 >2DLC-X nrPDB Length = 394 Score = 549 bits (1415), Expect = e-157, Method: Composition-based stats. Identities = 394/394 (100%), Positives = 394/394 (100%) Query: 1 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM 60 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM Sbjct: 1 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM 60 Query: 61 TKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLK 120 TKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLK Sbjct: 61 TKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLK 120 Query: 121 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF 180 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF Sbjct: 121 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF 180 Query: 181 LDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 LDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL Sbjct: 181 LDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 Query: 241 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI 300 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI Sbjct: 241 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI 300 Query: 301 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATP 360 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATP Sbjct: 301 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATP 360 Query: 361 QKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL 394 QKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL Sbjct: 361 QKSKKAKKPKNKGTKYPGATKTNEIATKLEETKL 394 >2CYA-A nrPDB Length = 364 Score = 389 bits (1000), Expect = e-109, Method: Composition-based stats. Identities = 106/366 (28%), Positives = 185/366 (50%), Gaps = 31/366 (8%) Query: 7 VDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADF 66 VD E F I +N E++ + +K +L R +K Y G P+G H G+ V M K+ D Sbjct: 4 VDVEERFNRIARNTVEIVTEEELKGLLASGAR-IKGYIGYEPSGVAHIGWLVWMYKVKDL 62 Query: 67 LKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGS 125 ++AG + +VL A HA++ D + ++++ A+ ++ ++ + VP+E+++FV Sbjct: 63 VEAGVDFSVLEATWHAYINDKLGGDMDLIRAAAR----IVRRVMEAAGVPVERVRFVDAE 118 Query: 126 SYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLL--SGLIYPLMQALDEQFLDV 183 DY + R++ S +RA + ++ + S LIYPLMQ D ++D+ Sbjct: 119 ELASDKDYWGLVIRVAKRASLARVRRALTIMGRRAEEAEVDASKLIYPLMQVSDIFYMDL 178 Query: 184 DCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG----------------K 227 D GG+DQRK +LA + LG KK + P++ L G K Sbjct: 179 DIALGGMDQRKAHMLARDVAEKLGRKKPVAIHTPIISSLQGPGRMEASQGEIDDVLAEVK 238 Query: 228 MSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFE 287 MS S P + + +++ +++KI A+C V+ N +L +Y++ F + F Sbjct: 239 MSKSKPETAVFVVDSDDDIRRKIRKAYCPAKQVQGNPVLEIARYIL-------FARDGFT 291 Query: 288 FFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEF 347 +DRP K+GGP+ Y S+EE++ + + +L P DLK VA+++ E++ PIR + Sbjct: 292 LRVDRPAKYGGPVEYTSYEELERDYTDGRLHPLDLKNAVAESLIEVVRPIRGAVLGDPAM 351 Query: 348 QEASEK 353 + A E Sbjct: 352 KRALEA 357 >2CYB-A nrPDB Length = 323 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 132/336 (39%), Positives = 200/336 (59%), Gaps = 16/336 (4%) Query: 7 VDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADF 66 +D E LIT+N +EV+ + ++ ++E +++ + Y G P+G H G+ + + KL D Sbjct: 1 MDITEKLRLITRNAEEVVTEEELRQLIETKEKP-RAYVGYEPSGEIHLGHMMTVQKLMDL 59 Query: 67 LKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSS 126 +AG E+ VLLAD+HA+L+ K E + A Y K + ++ + + KFV+GS Sbjct: 60 QEAGFEIIVLLADIHAYLNE-KGTFEEIAEVADYN----KKVFIALGLDESRAKFVLGSE 114 Query: 127 YQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQ 186 YQL+ DY +D+ +++ I + N A+R+ +V ++ +P++S +IYPLMQALD L VD Sbjct: 115 YQLSRDYVLDVLKMARITTLNRARRSMDEVSRRKEDPMVSQMIYPLMQALDIAHLGVDLA 174 Query: 187 FGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQV 246 GG+DQRKI +LA ENLP LGY L P++ GL KMS+S N I + + P++V Sbjct: 175 VGGIDQRKIHMLARENLPRLGYSSPVCLHTPILVGLDG-QKMSSSKGNY-ISVRDPPEEV 232 Query: 247 KKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFE 306 ++KI A+C G VEEN +L +Y I P +FG + ++R KFGG + Y SFE Sbjct: 233 ERKIRKAYCPAGVVEENPILDIAKYHILP----RFG----KIVVERDAKFGGDVEYASFE 284 Query: 307 EMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFA 342 E+ FK +L P DLKI VA +N LLE R+ Sbjct: 285 ELAEDFKSGQLHPLDLKIAVAKYLNMLLEDARKRLG 320 >4Q93-A nrPDB Length = 372 Score = 387 bits (995), Expect = e-108, Method: Composition-based stats. Identities = 201/363 (55%), Positives = 268/363 (73%), Gaps = 12/363 (3%) Query: 9 PNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLK 68 P E LIT+NLQEVL + +K++L+ +R LK+YWGTA TG+PH YFVPM+K+ADFLK Sbjct: 7 PEEKLHLITRNLQEVLGEEKLKEILK--ERELKIYWGTATTGKPHVAYFVPMSKIADFLK 64 Query: 69 AGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQ 128 AGCEVT+L ADLHA+LDNMKAP E++ R YYE IKA+L SI VP+EKLKF+ G+ YQ Sbjct: 65 AGCEVTILFADLHAYLDNMKAPWELLELRVSYYENVIKAMLESIGVPLEKLKFIKGTDYQ 124 Query: 129 LTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFG 188 L+ +YT+D++RLS++V+Q+D+K+AGA+VVKQV +PLLSGL+YP +QALDE++L VD QFG Sbjct: 125 LSKEYTLDVYRLSSVVTQHDSKKAGAEVVKQVEHPLLSGLLYPGLQALDEEYLKVDAQFG 184 Query: 189 GVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKK 248 G+DQRKIF AE+ LP+LGY KR HLMNPMVPGL KMS+S+ SKIDLL+ + VKK Sbjct: 185 GIDQRKIFTFAEKYLPALGYSKRVHLMNPMVPGLTG-SKMSSSEEESKIDLLDRKEDVKK 243 Query: 249 KINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEM 308 K+ AFC PGNVE NG+LSF+++V+ P++ EF I R EK+GG TY ++ ++ Sbjct: 244 KLKKAFCEPGNVENNGVLSFIKHVLFPLKS--------EFVILRDEKWGGNKTYTAYVDL 295 Query: 309 KLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKAKK 368 + F E + P DLK V A+N+LL+PIR++F N ++ + YP + QK Sbjct: 296 EKDFAAEVVHPGDLKNSVEVALNKLLDPIREKF-NTPALKKLASAAYPDPSKQKPMAKGP 354 Query: 369 PKN 371 KN Sbjct: 355 AKN 357 >2CYC-A nrPDB Length = 375 Score = 364 bits (934), Expect = e-101, Method: Composition-based stats. Identities = 115/378 (30%), Positives = 184/378 (48%), Gaps = 39/378 (10%) Query: 7 VDPNEAFGLITKN-LQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGY-FVPMTKLA 64 +D E L+ K +EVL + ++ + E+ L+ Y G +G H G + K+A Sbjct: 1 MDIEERINLVLKKPTEEVLTVENLRHLFEIGA-PLQHYIGFEISGYIHLGTGLMAGAKIA 59 Query: 65 DFLKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRA-KYYELTIKAILRSINVPIEKLKFV 122 DF KAG + V LAD H+++ D + LEV+ A KY+++ ++ + + +K++FV Sbjct: 60 DFQKAGIKTRVFLADWHSWINDKLGGDLEVIQEVALKYFKVGMEKSIEVMGGDPKKVEFV 119 Query: 123 VGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPLMQALDEQFL 181 + S DY + +S V+ + R+ + +Q+ + + LIYP+MQ D + Sbjct: 120 LASEILEKGDYWQTVIDISKNVTLSRVMRSITIMGRQMGEAIDFAKLIYPMMQVADIFYQ 179 Query: 182 DVDCQFGGVDQRKIFVLAEENLPSLGYK---------KRAHLMNPMVPGLAQ-------- 224 V G+DQRK V+A E L Y K + + ++ GL + Sbjct: 180 GVTIAHAGMDQRKAHVIAIEVAQKLRYHPIVHEGEKLKPVAVHHHLLLGLQEPPKWPIES 239 Query: 225 ---------GGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAP 275 KMS S P S + + + P+++++K+ AFC V N +L +V+Y+I Sbjct: 240 EEEFKEIKAQMKMSKSKPYSAVFIHDSPEEIRQKLRKAFCPAREVRYNPVLDWVEYII-- 297 Query: 276 IQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLE 335 F EF + RP KFGG +TY +FEE+K F E KL P DLK VA+ + LLE Sbjct: 298 -----FREEPTEFTVHRPAKFGGDVTYTTFEELKRDFAEGKLHPLDLKNAVAEYLINLLE 352 Query: 336 PIRQEFANNKEFQEASEK 353 PIR+ F + E E Sbjct: 353 PIRRYFEKHPEPLELMRS 370 >3VGJ-A nrPDB Length = 373 Score = 349 bits (896), Expect = 9e-97, Method: Composition-based stats. Identities = 103/351 (29%), Positives = 166/351 (47%), Gaps = 20/351 (5%) Query: 8 DPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFL 67 D ++ I E + P ++ L ++ R L Y G P+GR H + + + + L Sbjct: 26 DVDKILNDILSISSECIQPDELRVKLLLK-RKLICYDGFEPSGRMHIAQGLLKSIIVNKL 84 Query: 68 KA-GCEVTVLLADLHAFLDN-MKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGS 125 + GC +AD A L+N M L+ + Y+ + +S + +E ++F+ S Sbjct: 85 TSNGCTFIFWIADWFAHLNNKMSGDLKKIKKVGSYF----IEVWKSCGMNMENVQFLWAS 140 Query: 126 SYQLTP--DYTMDIFRLSNIVSQNDAKRAGADVVKQV-ANPLLSGLIYPLMQALDEQFLD 182 +Y + +S + N KR + + S ++YP MQ D FL+ Sbjct: 141 EEINKKPNEYWSLVLDISRSFNINRMKRCLKIMGRSEGEENYCSQILYPCMQCADIFFLN 200 Query: 183 VDCQFGGVDQRKIFVLAEENLPSLGYKK-RAHLMNPMVPGLAQGG-KMSASDPNSKIDLL 240 VD G+DQRK+ +LA E KK L + M+PGL +G KMS SD NS I + Sbjct: 201 VDICQLGIDQRKVNMLAREYCDIKKIKKKPVILSHGMLPGLLEGQEKMSKSDENSAIFMD 260 Query: 241 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPI 300 + V +KI A+C P +E N + ++ + +I P ++ EF + R EK GG Sbjct: 261 DSESDVNRKIKKAYCPPNVIENNPIYAYAKSIIFP--------SYNEFNLVRKEKNGGDK 312 Query: 301 TYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEAS 351 TY + +E++ + + P DLK VA IN+LL+P+R F NN E + Sbjct: 313 TYYTLQELEHDYVNGFIHPLDLKDNVAMYINKLLQPVRDHFQNNIEAKNLL 363 >5NSF-B nrPDB Length = 318 Score = 342 bits (878), Expect = 1e-94, Method: Composition-based stats. Identities = 107/331 (32%), Positives = 186/331 (56%), Gaps = 26/331 (7%) Query: 11 EAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAG 70 + F +I +N E+++ + +++VL+ ++ + G P+G+ H G+++ + K+ D AG Sbjct: 14 DEFEMIKRNTSEIISEEELREVLKKDEKSAGI--GFEPSGKIHLGHYLQIKKMIDLQNAG 71 Query: 71 CEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLT 130 ++ + LADL A+L N K L+ + Y K + ++ + K K+V GS + L Sbjct: 72 FDIIIWLADLGAYL-NQKGELDEIRKIGDYN----KKVFEAMGL---KAKYVYGSEHNLD 123 Query: 131 PDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGV 190 DYT++++RL+ + A+R+ + ++ NP ++ +IYP+MQ + VD GG+ Sbjct: 124 KDYTLNVYRLALKTTLKRARRSMELIAREDENPKVAEVIYPIMQVNAIHYNGVDVAVGGM 183 Query: 191 DQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKI 250 +QRKI +LA E LP KK + NP++ GL GKMS+S N I + + P++++ KI Sbjct: 184 EQRKIHMLARELLP----KKVVCIHNPVLTGLDGEGKMSSSKGNF-IAVDDSPEEIRAKI 238 Query: 251 NSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKL 310 A+C G VE N ++ +Y + + I RPEKFGG +T S+EE++ Sbjct: 239 KKAYCPAGVVEGNPIMEIAKYFL-----------EYPLTIKRPEKFGGDLTVNSYEELES 287 Query: 311 AFKEEKLSPPDLKIGVADAINELLEPIRQEF 341 FK ++L P LK VA+ + ++LEPIR+ Sbjct: 288 LFKNKELHPMRLKNAVAEELIKILEPIRKRL 318 >3P0I-A nrPDB Length = 690 Score = 340 bits (871), Expect = 7e-94, Method: Composition-based stats. Identities = 92/356 (25%), Positives = 165/356 (46%), Gaps = 16/356 (4%) Query: 7 VDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFV-PMTKLAD 65 ++ +E + L+ +E + +++++E +K ++ Y G P+GR H + + Sbjct: 9 MNTDERYKLLRSVGEECIQESELRNLIE-KKPLIRCYDGFEPSGRMHIAQGIFKAVNVNK 67 Query: 66 FLKAGCEVTVLLADLHAFL-DNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVG 124 AGCE +AD A + D + LE + +Y + + ++ + ++K+ F+ Sbjct: 68 CTAAGCEFVFWVADWFALMNDKVGGELEKIRIVGRY----LIEVWKAAGMDMDKVLFLWS 123 Query: 125 SSYQLT--PDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLD 182 S + Y + + + K+ + K + ++YPLMQ D FL Sbjct: 124 SEEITSHADTYWRMVLDIGRQNTIARIKKCCTIMGKTEGTLTAAQVLYPLMQCCDIFFLK 183 Query: 183 VDCQFGGVDQRKIFVLAEENLPSLGYK-KRAHLMNPMVPGLAQGG-KMSASDPNSKIDLL 240 D G+DQRK+ +LA E +G K K L + M+ GL QG KMS SDP+S I + Sbjct: 184 ADICQLGLDQRKVNMLAREYCDLIGRKLKPVILSHHMLAGLKQGQAKMSKSDPDSAIFME 243 Query: 241 EEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFI-DRPEKFG-- 297 + + V +KI A+C + + + ++F+ + RP Sbjct: 244 DTEEDVARKIRQAYCPRVKQSASAITD--DGAPVATDDRNPVLDYFQCVVYARPGAAATI 301 Query: 298 GPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEK 353 TY ++E+++ AF +++S LK + D +N LLEP+RQ FA+N+E E E Sbjct: 302 DGTTYATYEDLEQAFVSDEVSEDALKSCLIDEVNALLEPVRQHFASNEEAHELLEA 357 Score = 76.0 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 51/262 (19%), Positives = 93/262 (35%), Gaps = 24/262 (9%) Query: 72 EVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTP 131 VT++L D A + + V A+L++ +P +K V + L Sbjct: 417 TVTLVLPDWSAVASD---EITGVEKDISAALQVNCALLKAYGLP-SSVKIVTENEVILGN 472 Query: 132 --DYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGG 189 D+ + + ++ + + +V N +I LM+ L V Sbjct: 473 CDDFWVSVIGIARKNLLSHVE---ELYGGEVRN--AGQVIAALMRVATALMLSVSHVIST 527 Query: 190 VDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDP-NSKIDLLEEPKQVKK 248 I A E + +P L + G A + + L + +++ Sbjct: 528 SLDGHINAFAREYTKE--RIDCVQTLEGRIPALHRPGAAPAVLGADDVLYLDDNDMDIRR 585 Query: 249 KINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEM 308 KI A+ +P E N ++S Q+++A H I+R E GG ++Y + E + Sbjct: 586 KIKKAYSAPNE-EANPVISVAQHLLA---------QHGALSIERGEANGGNVSYNTPEAL 635 Query: 309 KLAFKEEKLSPPDLKIGVADAI 330 L P DLK V + Sbjct: 636 VADCGSGALHPADLKAAVLQLL 657 >2J5B-A nrPDB Length = 348 Score = 304 bits (777), Expect = 5e-83, Method: Composition-based stats. Identities = 78/363 (21%), Positives = 155/363 (42%), Gaps = 34/363 (9%) Query: 8 DPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGY-FVPMTKLADF 66 + + +E +K +++ R Y G P+GR H + + + Sbjct: 10 NNEHRLTQLLSIAEECETLDRLKQLVDS-GRIFTAYNGFEPSGRIHIAQALITVMNTNNM 68 Query: 67 LKAGCEVTVLLADLHAFLD-NMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGS 125 ++ G ++ + +AD A ++ M + + +Y+ + ++ + ++ +F+ S Sbjct: 69 IECGGQMIIYIADWFAKMNLKMNGDINKIRELGRYF----IEVFKACGINLDGTRFIWAS 124 Query: 126 SY-QLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPLMQALDEQFL-- 181 + P Y + ++ + + KR + + ++ L S + YP MQA D L Sbjct: 125 EFIASNPSYIERMLDIAEFSTISRVKRCCQIMGRNESDCLKASQIFYPCMQAADVFELVP 184 Query: 182 -DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDL 239 +D G+DQRK+ +LA E G K L + M+ L+ KMS SDP I + Sbjct: 185 EGIDICQLGIDQRKVNMLAIEYANDRGLKIPISLSHHMLMSLSGPKKKMSKSDPQGAIFM 244 Query: 240 LEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGP 299 + ++V +KI+ A+C+ +N + +++Y++ FGT + G Sbjct: 245 DDTEQEVSEKISRAYCTDETF-DNPIFEYIKYLLLRW----FGTLN----------LCGK 289 Query: 300 ITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASE--KGYPV 357 I Y E ++ F ++ +LK VA+ IN +++ +R+ F E E K Y Sbjct: 290 I-YTDIESIQEDFSS--MNKRELKTDVANYINTIIDLVREHFKK-PELSELLSNVKSYQQ 345 Query: 358 ATP 360 + Sbjct: 346 PSK 348 >6BQZ-A nrPDB Length = 408 Score = 230 bits (586), Expect = 1e-60, Method: Composition-based stats. Identities = 76/296 (25%), Positives = 127/296 (42%), Gaps = 32/296 (10%) Query: 10 NEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLK 68 E LI + E+++ + + L+ + R LK+ G PT H G+ V + KL F Sbjct: 12 EEQLALIQRGTHEIISEEDLLKKLK-ENRPLKIKAGFDPTAPDLHLGHTVLINKLKTFQD 70 Query: 69 AGCEVTVLLADLHAFLDN------MKAPL--EVVNYRAKYYELTIKAILRSINVPIEKLK 120 G EVT L+ D A + + + PL E V AK Y+ + + + ++ K++ Sbjct: 71 LGHEVTFLIGDYTAMIGDPTGKSATRPPLSREQVEANAKTYQ---EQVFKILDPNKTKVR 127 Query: 121 FVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRA--GADVVKQVAN---PLLSGLIYPLMQA 175 F +S D+ +L+ SQ R D K+ N + +YPL+Q Sbjct: 128 F---NSEWFNQKSAADLIQLA---SQQTVSRMLERDDFTKRYNNHQPIAIHEFLYPLVQG 181 Query: 176 LDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNS 235 D L+ D + GG DQ ++ G + + + P++ GL KMS S N Sbjct: 182 YDSIALEADVELGGTDQTFNLLMGRTLQSRYGQESQVCITVPILEGLDGVNKMSKSLGNY 241 Query: 236 KIDLLEEPKQVKKKINSAFCSPGNVEEN--GLLSF--VQYVIAPIQELKFGTNHFE 287 I + + P + +K+ P ++ E LLSF + + A + E+ G N E Sbjct: 242 -IGVFDAPGAMYQKV---LSMPDSLIERYFDLLSFKSLDEIKALLDEIAAGRNPQE 293 >1H3F-A nrPDB Length = 432 Score = 215 bits (547), Expect = 3e-56, Method: Composition-based stats. Identities = 64/260 (24%), Positives = 111/260 (42%), Gaps = 25/260 (9%) Query: 9 PNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFL 67 P EA L+ + +E++ + + L+ + R L + G PT H G+ V + K+ F Sbjct: 8 PEEALALLKRGAEEIVPEEELLAKLK-EGRPLTVKLGADPTRPDLHLGHAVVLRKMRQFQ 66 Query: 68 KAGCEVTVLLADLHAFLD------NMKAP--LEVVNYRAKYYELTIKAILRSINVPIE-- 117 + G +V +++ D + + P LE AK Y ILR E Sbjct: 67 ELGHKVVLIIGDFTGMIGDPSGRSKTRPPLTLEETRENAKTYVAQAGKILRQEPHLFELR 126 Query: 118 -KLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKR---AGADVVKQVANPLLSGLIYPLM 173 +++ G +++ T + ++ ++ + D K+ AG + L L+YP Sbjct: 127 YNSEWLEGLTFKEVVRLT-SLMTVAQMLEREDFKKRYEAGIPIS-------LHELLYPFA 178 Query: 174 QALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDP 233 QA D + D + GG DQR ++ E + G + + P++ GL KMS S Sbjct: 179 QAYDSVAIRADVEMGGTDQRFNLLVGREVQRAYGQSPQVCFLMPLLVGLDGREKMSKSLD 238 Query: 234 NSKIDLLEEPKQVKKKINSA 253 N I L E P+ + KK+ Sbjct: 239 NY-IGLTEPPEAMFKKLMRV 257 >3JXE-A nrPDB Length = 392 Score = 188 bits (476), Expect = 4e-48, Method: Composition-based stats. Identities = 67/235 (28%), Positives = 97/235 (41%), Gaps = 18/235 (7%) Query: 28 IIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPM--TKLADFLKAGCEVTVLLADLHAFLD 85 I+KD E R LY G P+G H G+ +P TK K G + + + D FL Sbjct: 64 ILKDYEE--GRGFFLYTGRGPSGPMHIGHIIPFFATKWLQ-EKFGVNLYIQITDDEKFL- 119 Query: 86 NMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVS 145 K L + + Y+ IL I V + K + + + T Y M I I Sbjct: 120 -FKENLTFDDTKRWAYD----NILDIIAVGFDPDKTFIFQNSEFTKIYEMAI----PIAK 170 Query: 146 QNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGG-VDQRKIFVLAEENLP 204 + + A A V + + +P +Q F C +DQ + L + Sbjct: 171 KINFSMAKA-VFGFTEQSKIGMIFFPAIQIAPTFFERKRCLIPAAIDQDPYWRLQRDFAE 229 Query: 205 SLGYKKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPG 258 SLGY K A L + VP L GKMSAS P + I L + P+ V+KK+ + G Sbjct: 230 SLGYYKTAALHSKFVPSLTSLSGKMSASKPETAIYLTDSPEDVEKKVWKFTLTGG 284 >6BYQ-A nrPDB Length = 410 Score = 183 bits (465), Expect = 8e-47, Method: Composition-based stats. Identities = 74/362 (20%), Positives = 135/362 (37%), Gaps = 64/362 (17%) Query: 12 AFGLITKNLQEVLN----PQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADF 66 A I + E++ ++++ E +R + G PT H G+ V + KLA Sbjct: 16 ALKEIKRGANEIIGLEYIEKLVRKYYETNER-FIVKAGFDPTAPDLHLGHTVLIQKLALL 74 Query: 67 LKAGCEVTVLLADLHAFL------DNMKAPL--EVVNYRAKYYELTIKAILRSINVPIEK 118 + G V L+ D A + + + PL E V AK YE I IL + + Sbjct: 75 QQYGARVKFLIGDFTAMIGDPTGKNETRKPLNREQVLENAKTYEEQIYKILDQKHTEV-- 132 Query: 119 LKFVVGSSY--QLTPDYTMDI---FRLSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPL 172 S++ L +++ F ++ ++ ++D + + P+ + +YPL Sbjct: 133 ---CFNSTWLDALGAKGMIELCAKFSVARMLERDDFAK-----RHKENRPISIVEFLYPL 184 Query: 173 MQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKK-RAHLMNPMVPGLAQGGKMSAS 231 +Q D + D + GG DQ+ ++ + G K ++ + P++ GL KMS S Sbjct: 185 LQGYDSVAMGADIELGGNDQKFNLLVGRFLQRAYGLNKEQSIITMPLLEGLDGVQKMSKS 244 Query: 232 DPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFID 291 N + + EEP + KI S + L + Y + Sbjct: 245 LGNY-VGITEEPNAMFGKIMSV---------SDDLMWRYYTLLSA--------------- 279 Query: 292 RPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEAS 351 T + E++K + L P +K +A I Q F ++F + Sbjct: 280 --------KTLEEIEDLKHGILNQTLHPKAVKEDLAGEIVARYYDNDQAFKAKEQFSKVF 331 Query: 352 EK 353 Sbjct: 332 SA 333 >5UJI-A nrPDB Length = 388 Score = 164 bits (415), Expect = 6e-41, Method: Composition-based stats. Identities = 68/341 (19%), Positives = 116/341 (34%), Gaps = 45/341 (13%) Query: 37 KRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLK-AGCEVTVLLADLHAFLDNMKAPLEVV 94 K+ LY G P+ H G+ +P + + + D +L L + Sbjct: 57 KKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWK---DLTLD 113 Query: 95 NYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGA 154 Y ++ I + K + S + + I + Sbjct: 114 QA----YSYAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKG 169 Query: 155 DVVKQVANPLLSGLIYPLMQALDEQFL--------DVDCQ---FGGVDQRKIFVLAEENL 203 ++ + + +P +QA D Q +DQ F + + Sbjct: 170 IFGFTDSDC-IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVA 228 Query: 204 PSLGYKKRAHLMNPMVPGLAQGG-KMSASDPNSKIDLLEEPKQVKKKINSAFCSPG--NV 260 P +GY K A L + P L KMSASDPNS I L + KQ+K K+N S G + Sbjct: 229 PRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTI 288 Query: 261 EENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPP 320 EE+ V + FF++ +K E+++ + + Sbjct: 289 EEHRQFGGNCDVDVSFM-------YLTFFLEDDDK---------LEQIRKDYTSGAMLTG 332 Query: 321 DLKIGVADAINELLEP-IRQEFANNKEFQEASEKGYPVATP 360 +LK A+ E+L+P I + A KE + K + Sbjct: 333 ELK----KALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRK 369 >1R6T-A nrPDB Length = 477 Score = 163 bits (411), Expect = 2e-40, Method: Composition-based stats. Identities = 68/341 (19%), Positives = 116/341 (34%), Gaps = 45/341 (13%) Query: 37 KRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLK-AGCEVTVLLADLHAFLDNMKAPLEVV 94 K+ LY G P+ H G+ +P + + + D +L L + Sbjct: 153 KKPFYLYTGRGPSSEAMHVGHLIPFIFTKWLQDVFNVPLVIQMTDDEKYLWK---DLTLD 209 Query: 95 NYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGA 154 Y ++ I + K + S + + I + Sbjct: 210 QA----YGDAVENAKDIIACGFDINKTFIFSDLDYMGMSSGFYKNVVKIQKHVTFNQVKG 265 Query: 155 DVVKQVANPLLSGLIYPLMQALDEQFL--------DVDCQ---FGGVDQRKIFVLAEENL 203 ++ + + +P +QA D Q +DQ F + + Sbjct: 266 IFGFTDSDC-IGKISFPAIQAAPSFSNSFPQIFRDRTDIQCLIPCAIDQDPYFRMTRDVA 324 Query: 204 PSLGYKKRAHLMNPMVPGLAQGG-KMSASDPNSKIDLLEEPKQVKKKINSAFCSPG--NV 260 P +GY K A L + P L KMSASDPNS I L + KQ+K K+N S G + Sbjct: 325 PRIGYPKPALLHSTFFPALQGAQTKMSASDPNSSIFLTDTAKQIKTKVNKHAFSGGRDTI 384 Query: 261 EENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPP 320 EE+ V + FF++ +K E+++ + + Sbjct: 385 EEHRQFGGNCDVDVSFM-------YLTFFLEDDDK---------LEQIRKDYTSGAMLTG 428 Query: 321 DLKIGVADAINELLEP-IRQEFANNKEFQEASEKGYPVATP 360 +LK A+ E+L+P I + A KE + K + Sbjct: 429 ELK----KALIEVLQPLIAEHQARRKEVTDEIVKEFMTPRK 465 >3HV0-A nrPDB Length = 393 Score = 153 bits (387), Expect = 1e-37, Method: Composition-based stats. Identities = 65/352 (18%), Positives = 119/352 (33%), Gaps = 46/352 (13%) Query: 27 QIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLK-AGCEVTVLLADLHAFL 84 + I DV E + LY G P+ H G+ VP + + L D F+ Sbjct: 63 EKILDVYEKGE-LFYLYTGRGPSSESLHVGHLVPFLFTKYLQDTFKVPLVIQLTDDEKFI 121 Query: 85 DNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIV 144 K+ L + YE + I + + ++ + + DI R+ + Sbjct: 122 --FKSNLTLEETHNYAYE----NMKDIIACGFDPELTFIFTNLEYIAELYPDILRIEKKI 175 Query: 145 SQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQF----------LDVDCQFG-GVDQR 193 S + K + + + +P +QA D+ C +DQ Sbjct: 176 SCSQIK----SIFGFKDSCNVGKFAFPAVQAAPAFSSSFPHIFGGRTDIHCLVPHAIDQD 231 Query: 194 KIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG-KMSASDPNSKIDLLEEPKQVKKKINS 252 F + + P LGY K + + + +P L KMSAS NS I + + + ++ KI Sbjct: 232 PYFRMVRDVAPRLGYLKPSSIHSIFLPSLQGSQTKMSASVQNSSIFVNDNEESIRNKIMK 291 Query: 253 AFCSPGNV--EENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKL 310 S G EE L V Q L+F E EE+ Sbjct: 292 YAFSGGQATEEEQRRLGANLDVDVSWQYLRFLMEDDE----------------KLEEIGK 335 Query: 311 AFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQK 362 + ++ ++K + + +L + N + + + + ++ Sbjct: 336 KYSSGEMLSGEIKSILVQELVKL---TKNHQKNREAINDDVIAKFTNKSREQ 384 >3I05-A nrPDB Length = 395 Score = 149 bits (377), Expect = 1e-36, Method: Composition-based stats. Identities = 63/276 (22%), Positives = 97/276 (35%), Gaps = 30/276 (10%) Query: 29 IKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLK-AGCEVTVLLADLHAFLDN 86 + DV E + LY G P+ H G+ +P + + + D F Sbjct: 69 LLDVYES-GQPFYLYTGRGPSSESMHMGHLIPFMFTKWLQDSFRVPLVIQMTDDEKFYFR 127 Query: 87 MKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQ 146 P+E V +T + I I + + + + DY ++R + + Sbjct: 128 -NIPMEQVEA------MTTENIKDIIAMGFDPELTFIFRDF----DYMGCMYRTVAKIER 176 Query: 147 NDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFL-----------DVDCQFG-GVDQRK 194 ++P +QA +V C +DQ Sbjct: 177 AFTASQVRGCFGFAMEDNCGRWMFPAIQAAPSFSAAFPHIFPPSMGNVFCLIPQAIDQDP 236 Query: 195 IFVLAEENLPSLGYKKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVKKKINSA 253 F L + P LGY K A + + PGL+ GKMS+S + + L + K VK KIN Sbjct: 237 YFRLTRDIAPRLGYLKPAVIHSKFFPGLSGPKGKMSSSSG-TAVLLTDTEKMVKDKINKH 295 Query: 254 FCSPGNV--EENGLLSFVQYVIAPIQELKFGTNHFE 287 S G +E+ LL V PIQ L F E Sbjct: 296 AFSGGGATKQEHFLLGANVEVDVPIQWLSFFLEDDE 331 >3KT6-A nrPDB Length = 438 Score = 144 bits (363), Expect = 6e-35, Method: Composition-based stats. Identities = 79/389 (20%), Positives = 135/389 (34%), Gaps = 55/389 (14%) Query: 11 EAFGLITKNLQEVLNPQIIKDVLEV--QKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFL 67 E + K L + + +L++ Q + LY G P+ H G+ +P Sbjct: 74 EPHHFLRKGL--FFSERDFTKILDLYEQGKPFFLYTGRGPSSDSMHLGHMIPFVFTKWLQ 131 Query: 68 K-AGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSS 126 + + + L D FL K + V A+ + I V + + S Sbjct: 132 EVFDVPLVIELTDDEKFLFKHKLTINDVKNFAR------ENAKDIIAVGFDPKNTFIFSD 185 Query: 127 YQ-LTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQ------ 179 Q + + + R+S ++ + AK V + + + +Q Sbjct: 186 LQYMGGAFYETVVRVSRQITGSTAK----AVFGFNDSDCIGKFHFASIQIATAFPSSFPN 241 Query: 180 FLDVD-----CQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG-KMSASDP 233 L + +DQ F + + L Y K A L + P L KMSASD Sbjct: 242 VLGLPDKTPCLIPCAIDQDPYFRVCRDVADKLKYSKPALLHSRFFPALQGSTTKMSASDD 301 Query: 234 NSKIDLLEEPKQVKKKINSAFCSPGNVEE--NGLLSFVQYVIAPIQELKFGTNHFEFFID 291 + I + + PKQ++KKIN S G V + L V Q L F + F Sbjct: 302 TTAIFMTDTPKQIQKKINKYAFSGGQVSADLHRELGGNPDVDVAYQYLSFFKDDDVF--- 358 Query: 292 RPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEAS 351 +E +K +L ++K + + E ++ ++ A E E Sbjct: 359 -------------LKECYDKYKSGELLSGEMKKLCIETLQEFVKAFQERRAQVDE--ETL 403 Query: 352 EKGYPVATP-----QKSKKAKKPKNKGTK 375 +K + V ++ A KPK K K Sbjct: 404 DK-FMVPHKLVWGEKERLVAPKPKTKQEK 431 >3TZE-A nrPDB Length = 406 Score = 140 bits (353), Expect = 9e-34, Method: Composition-based stats. Identities = 64/285 (22%), Positives = 111/285 (38%), Gaps = 25/285 (8%) Query: 37 KRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKA-GCEVTVLLADLHAFLDNMKAPLEVV 94 R LY G P+ + H G+ +P A + + + D FL + + Sbjct: 99 NRPFYLYTGRGPSSKTMHIGHTIPFLLCKYMQDAFKIRLVIQITDDEKFLWK---SMRLE 155 Query: 95 NYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGA 154 + A + I + + + + S+ + + + +I ++S ++ N+A + Sbjct: 156 DAMA----YGRENIKDIVTLGFDPKLTYIFSNVEASHHFEENILKISKTINLNEAIK--- 208 Query: 155 DVVKQVANPLLSGLIYPLMQALDEQ-----FLDVD---CQFGGVDQRKIFVLAEENLPSL 206 V + + + +P + F+ VDQ F LA + +L Sbjct: 209 -VFGFDMSSNIGQVGFPAKEIAPCFSSSFRFIGKGAMCLVPAAVDQDPFFRLARDKAKAL 267 Query: 207 GYKKRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPG--NVEEN 263 G KK + + ++P L KMSASDPNS I L + ++KKI + S G +EE+ Sbjct: 268 GEKKPSSIYVSLLPDLKGVNRKMSASDPNSSIYLDDAQDTIRKKIIAYAYSGGRKTLEEH 327 Query: 264 GLLSFVQYVIAPIQELK-FGTNHFEFFIDRPEKFGGPITYKSFEE 307 V P + LK F + E R G IT K +E Sbjct: 328 REKGGDIDVDVPFEYLKYFLDDDQELEKYRSGYIKGEITSKEMKE 372 >3FOC-A nrPDB Length = 451 Score = 133 bits (334), Expect = 2e-31, Method: Composition-based stats. Identities = 73/369 (19%), Positives = 123/369 (33%), Gaps = 81/369 (21%) Query: 27 QIIKDVLEVQKRHLKLYWGTAPT-GRPHCGYFVPMTKLADFLKA-GCEVTVLLADLHAFL 84 + E + + +Y G P+ G H G+ +P A C V + + D FL Sbjct: 80 EEFLSYYE-KGHPIYIYTGRGPSSGALHLGHLLPFIFTKYLQDAFKCYVVIQITDDEKFL 138 Query: 85 DNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPD---YTMDIFRLS 141 N V+ Y + + +K + S Y + ++ + R+ Sbjct: 139 RNRSLSYAEVDS----YTRENIKDIIACGFDPDKTFIFINSQYLSLKNRYRFSCLVDRML 194 Query: 142 NIVSQ----------------------------------------------NDAKRAGAD 155 I DA A + Sbjct: 195 PISQLRASFGFSNDANVGYAAFPPKQMLPVYSTYFDGLPFTRVPLPVGTGNEDAADAVST 254 Query: 156 VVKQVANPLLSGLIYPLMQALDEQ-----FLDVDCQFG-GVDQRKIFVLAEENLPSLGYK 209 P ++ P+ + + C G++Q F LA + P +G+ Sbjct: 255 KKASKKTPKKDAVLSPVHVVEELFPDSKRYQKAMCLIASGIEQDPYFRLARDLAPRMGHP 314 Query: 210 KRAHLMNPMVPGLAQ-GGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPG--NVEENGLL 266 K A+L+ +PGL G KMSASDPNS I L + P Q+K KIN S G EE+ Sbjct: 315 KNAYLLGKFLPGLQGSGTKMSASDPNSAIYLTDTPAQIKNKINRYAFSGGRDTEEEHRAF 374 Query: 267 SFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGV 326 V ++ + E F+ + E++K +K KL ++K + Sbjct: 375 GADLSVDVSVR-------YLEVFMKDDAE---------LEKLKADYKTGKLLTGEVKATL 418 Query: 327 ADAINELLE 335 + L++ Sbjct: 419 IGILQGLIK 427 >4J75-A nrPDB Length = 409 Score = 125 bits (314), Expect = 3e-29, Method: Composition-based stats. Identities = 61/368 (16%), Positives = 122/368 (33%), Gaps = 59/368 (16%) Query: 29 IKDVLEVQKRHLKLYWGTAPTG-RPHCGYFVPMTKLADFLKA-GCEVTVLLADLHAFLDN 86 + + E Q + +Y G P+ H G+ +P +A + + L+D +L N Sbjct: 70 LLNYYE-QHKCFYIYTGRGPSSLSMHLGHLIPFYFCKYLQEAFNVPLVIQLSDDEKYLFN 128 Query: 87 MKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQ 146 LE +N T + + I+V + + + + + + + Sbjct: 129 QNYSLEYINTL------TNENVKDIISVGLNPELTFIFKNTEYAGYLYPTVLSIHKKTTL 182 Query: 147 NDAKRAGADVVKQVANPLLSGLIYPLMQALDEQ------FLDVDC---QFGGVDQRKIFV 197 N + +V + + + YP Q FL + G+DQ F Sbjct: 183 NQSM----NVFGFNHSDNIGKISYPSFQIAPCFSQCFPNFLGKNIPCLVPQGIDQDPYFR 238 Query: 198 LAEENLPSLGYKKRAHLMNPMVPGLAQ--------------GGKMSASDP--NSKIDLLE 241 L+ + + K + + +PGL GK +++ NS I L + Sbjct: 239 LSRDIAVKMALHKPVVVHSVFMPGLQGVNSKMSSTKKKKDDNGKSNSTFDHNNSVIFLTD 298 Query: 242 EPKQVKKKINSAFCSPG--NVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGP 299 P+Q+K KIN S G ++E+ Q L++ Sbjct: 299 TPEQIKNKINKYAFSGGGTTIQEHREKGGNLDKDISYQYLRYLLEDD------------- 345 Query: 300 ITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVAT 359 E+ +K+ ++ ++K + D + EL + + K + + Sbjct: 346 ---NKLNEIGEKYKKGEMLSGEIKKILIDVLTEL---VLKHQEKKKSLTDEEISYFFDPN 399 Query: 360 PQKSKKAK 367 +K K Sbjct: 400 KPSLQKFK 407 >3A04-A nrPDB Length = 372 Score = 119 bits (297), Expect = 3e-27, Method: Composition-based stats. Identities = 64/350 (18%), Positives = 121/350 (34%), Gaps = 50/350 (14%) Query: 15 LITKNLQEVLNPQIIKDVLEVQKRH--LKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCE 72 L+ + + + + +LE + R + + G P+G+ H G+ + + +L K G + Sbjct: 46 LMRRGI--IFGHRDFDKILEAKARGERVAVLTGFMPSGKFHFGHKLTVDQLIYLQKNGFK 103 Query: 73 VTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPD 132 V V +AD AF E V + Y + ++ + + +F ++ Sbjct: 104 VFVAIADAEAFAVRRIGREEAVRIAVEEYIANMI----ALGLDPKDTEFYFQTN-----R 154 Query: 133 YTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVD-------- 184 T + + A A + + ++ L QA D + +D Sbjct: 155 GTPYFRLIQLFSGKVTAAEMEAIYGELTP----AKMMASLTQAADILHVQLDEYGGYRHV 210 Query: 185 CQFGGVDQRKIFVLAEENLPSLG----YKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 G DQ L + + ++ A + + PGL KMS+S P+S I L Sbjct: 211 VVPVGADQDPHLRLTRDLADRMAGVVELERPASTYHKLQPGLDG-RKMSSSRPDSTIFLT 269 Query: 241 EEPKQVKKKINSAFCSPGNVEEN-----------GLLSFVQYVIAPIQELKFGTNHFEFF 289 + P+ + K+ A E + Y + P G + Sbjct: 270 DPPEVARNKLFRALTGGRATAEEQRRLGGVPEVCSVYHMDLYHLMPDD----GEVKHIYT 325 Query: 290 IDRPEK-FGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLEPIR 338 R K G ++E+++ E L+ A +L+EP R Sbjct: 326 SCRLGKILCGECKQIAWEKLERFLAE---HQSRLEKAKTIAW-KLVEPPR 371 >1YID-B nrPDB Length = 351 Score = 109 bits (273), Expect = 2e-24, Method: Composition-based stats. Identities = 68/316 (21%), Positives = 106/316 (33%), Gaps = 52/316 (16%) Query: 44 WGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYEL 103 G PTG H G+ + L+ E+ VLLAD+ A D+ P E V L Sbjct: 27 TGDRPTGALHLGHLAGSLQNRVRLQDEAELFVLLADVQALTDHFDRP-EQVRENVLAVAL 85 Query: 104 TIKAILRSINVPIEKLKFVVGS---SYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQV 160 + + +K VV S Y +++ +S+ + QN +A Sbjct: 86 DYL----AAGLDPQKTTCVVQSAVPELAELTVYFLNLVTVSH-LRQNPTVKAEIAQKGYG 140 Query: 161 ANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEE--------NLPSLGYKKRA 212 +YP+ QA D G DQ + E P L + Sbjct: 141 ERVPAGFFVYPVSQAADIAAFGATLVPVGDDQLPMLEQTREIVRRFNALYAPVLAEPQAQ 200 Query: 213 HLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAF--------CSPGNVEENG 264 P +PGL KMS S N I L + +V +K+ + PG VE N Sbjct: 201 LSRVPRLPGLDGQAKMSKSLGN-AIALGDSADEVARKVMGMYTDPGHLRASDPGRVEGNP 259 Query: 265 LLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKI 324 + +F+ F + + +K ++ L +K Sbjct: 260 VFTFLD---------AFDPDP-----------------ARVQALKDQYRAGGLGDVKVKK 293 Query: 325 GVADAINELLEPIRQE 340 + D +N +L PIR Sbjct: 294 HLIDVLNGVLAPIRTR 309 >2EL7-A nrPDB Length = 337 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 66/329 (20%), Positives = 117/329 (35%), Gaps = 55/329 (16%) Query: 41 KLYWGTAPTGRPHCGYFVPMTK--LADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRA 98 ++ G P+G H G ++ K +A K G + + D HA + + + Sbjct: 3 RVLSGIQPSGEIHIGNYLGAIKQWVAIGEKLGRDAFFCIVDYHALTNPLAYDPSTLAQ-- 60 Query: 99 KYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVK 158 + +E + I + + EK+ V S + + L+ + + K Sbjct: 61 RTFEAALVNI--AAGLDPEKVTLFVQSHVPEHTELSWVFTTLTPLGDLTRMTQFKDKASK 118 Query: 159 QVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGY------KKRA 212 Q L+YP++QA D D G DQ + L E + + Sbjct: 119 Q-ETVWSGLLMYPVLQAADILIYKADTVPVGEDQVQHIELTREIARRFNHLFGETFPEPQ 177 Query: 213 HLMN---PMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKI--------NSAFCSPGNVE 261 L+N P VPG+ KMS S N+ I LLE + + +KI PG+ E Sbjct: 178 ALLNPEAPRVPGIDGKAKMSKSLGNT-IGLLEPEESIWQKIQHLPDDPQRIRLSDPGDPE 236 Query: 262 ENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPD 321 L +++ Y AP + E +K +++ + Sbjct: 237 RTILFTYLSYF-APKDLV--------------------------EALKEEYRKAGVGTYV 269 Query: 322 LKIGVADAINELLEPIRQE---FANNKEF 347 +K + D + E L PIR+ + ++ Sbjct: 270 VKRILFDHLMEALRPIRERAEALKKDPDY 298 >3PRH-A nrPDB Length = 388 Score = 105 bits (262), Expect = 3e-23, Method: Composition-based stats. Identities = 66/347 (19%), Positives = 122/347 (35%), Gaps = 45/347 (12%) Query: 41 KLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKY 100 ++ G P+G G ++ K L+ + D HA + + Sbjct: 37 TIFSGIQPSGSVTLGNYIGAMKQFVELQHDYNSYFCIVDQHAI------TVPQDRLELRK 90 Query: 101 YELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQV 160 + A+ ++ + EK + S + ++ I + + Sbjct: 91 NIRNLAALYLAVGLDPEKATLFIQSEVPAHAQAGWMMQCVAYIGELERMTQFKDK--SKG 148 Query: 161 ANPLLSGLI-YPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNP-- 217 ++SGL+ YP + A D D G DQ++ L K P Sbjct: 149 NEAVVSGLLTYPPLMAADILLYGTDLVPPGEDQKQHLELTRNLAERFNKKYNDIFTIPEV 208 Query: 218 -------MVPGLAQG-GKMSASDPNSK--IDLLEEPKQVKKKINSAFCSPGNVEENGLLS 267 + L KMS SDPN K I LL+EPKQ++KKI SA + G++ Sbjct: 209 KIPKVGARIMSLNDPLKKMSKSDPNQKAYITLLDEPKQLEKKIKSAVT-----DSEGIVK 263 Query: 268 FVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVA 327 F + + L + + + EE++ ++ + + K +A Sbjct: 264 FDKENKPGVSNLLTIYSI--------------LGNTTIEELEAKYEGKGY--GEFKGDLA 307 Query: 328 DAINELLEPIRQEF---ANNKEFQEASEKGYPVATPQKSKKAKKPKN 371 + + L+PI+ + ++E ++G A +K KK +N Sbjct: 308 EVVVNALKPIQDRYYELIESEELDRILDEGAERANRTANKMLKKMEN 354 >2G36-A nrPDB Length = 340 Score = 102 bits (255), Expect = 2e-22, Method: Composition-based stats. Identities = 50/245 (20%), Positives = 82/245 (33%), Gaps = 18/245 (7%) Query: 31 DVLEVQKRHLKLYWGTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHAFLDNMKA 89 D + H+++ G PTG+ H G+ V + + G E +AD HA L Sbjct: 4 DKIHHHHHHMRILSGMRPTGKLHIGHLVGALENWVKLQEEGNECFYFVADWHA-LTTHYD 62 Query: 90 PLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDA 149 + + Y + + + EK V S + + + + ++ Sbjct: 63 DVSKLKE----YTRDLVRGFLACGIDPEKSVIFVQSGVKEHAELALLFSMIVSVSRLERV 118 Query: 150 KRAGADVVK--QVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLG 207 + LIYP++QA D + G DQ L E Sbjct: 119 PTYKEIKSELNYKDLSTAGFLIYPVLQAADILIYKAEGVPVGEDQVYHIELTREIARRFN 178 Query: 208 Y-------KKRAHLM-NPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGN 259 Y + A L P +PG KMS S N I+L K++++ I P Sbjct: 179 YLYDEVFPEPEAILSRVPKLPGTDG-RKMSKSYGN-IINLEISEKELEQTILRMMTDPAR 236 Query: 260 VEENG 264 V + Sbjct: 237 VRRSD 241 >6NCR-A nrPDB Length = 354 Score = 102 bits (253), Expect = 3e-22, Method: Composition-based stats. Identities = 66/353 (18%), Positives = 127/353 (35%), Gaps = 53/353 (15%) Query: 38 RHLKLYWGTAPTGRPHCGYFV--PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVN 95 + ++ G PTG+ H G+++ M +L + + ++ADLH + E++ Sbjct: 10 KKKRVLTGDRPTGKLHLGHWIGSIMNRLQLQNDSRYDCFFIIADLHTLTTKTRKE-EILQ 68 Query: 96 YRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGAD 155 Y++ S+ + EK + S+ + + L+ + + + Sbjct: 69 IDNHIYDVLAD--WLSVGIDPEKSAIYLQSAIPEIYELNLIFSMLTPLNHIMGIP-SIKE 125 Query: 156 VVKQV---ANPLLSGLI-YPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGY--- 208 + + L GLI YP++Q+ D G D L + + Sbjct: 126 MARNASLNEESLSHGLIGYPVLQSADILLAKAHLVPVGKDNEAHVELTRDIAKTFNRLYG 185 Query: 209 ---KKRAHLMNPM--VPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINS--------AFC 255 + L + + G GKMS S N+ I L ++ K V++KI Sbjct: 186 EVFPEPDILQGELTALVGTNGQGKMSKS-ANNAIYLSDDAKTVQEKIRKLYTDPNRIHAT 244 Query: 256 SPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEE 315 +PG VE N L + H F + E EE K +++ Sbjct: 245 TPGRVEGNPLFIY----------------HDLFNPHKEE----------VEEFKTRYRQG 278 Query: 316 KLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKAKK 368 + ++K +A+ IN L P R++ + + E+ T + A++ Sbjct: 279 CIRDVEVKARLAEEINLFLNPFREKRSELVAQPKFLEEALQQGTEKMRTVARE 331 >5V0I-A nrPDB Length = 337 Score = 97.2 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 67/343 (19%), Positives = 121/343 (35%), Gaps = 43/343 (12%) Query: 42 LYWGTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKY 100 ++ G P+G G ++ + + + + D HA ++ + + Sbjct: 9 VFSGAQPSGELTIGNYMGALRQWVNMQD-DYHCIYCIVDQHAI--TVRQDAQKLRKA--- 62 Query: 101 YELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQV 160 L A+ + + EK V S + + + + + Sbjct: 63 -TLDTLALYLACGIDPEKSTIFVQSHVPEHAQLGWALNCYTYFGELSRMTQFKDKSARYA 121 Query: 161 ANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLG--YKKRAHLMNPM 218 N YP++ A D + G DQ++ L+ + Y + P Sbjct: 122 ENINAGLFDYPVLMAADILLYQTNLVPVGEDQKQHLELSRDIAQRFNALYGDIFKVPEPF 181 Query: 219 VPG--------LAQGGKMSASDP--NSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSF 268 +P L KMS SD N+ I LLE+PK V KKI A E ++ + Sbjct: 182 IPKSGARVMSLLEPTKKMSKSDDNRNNVIGLLEDPKSVVKKIKRAVTDSD---EPPVVRY 238 Query: 269 VQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVAD 328 A + L + +T +S E++ F E K+ LK VAD Sbjct: 239 DVQNKAGVSNLLDILSA--------------VTGQSIPELEKQF-EGKMY-GHLKGEVAD 282 Query: 329 AINELLEPIRQ---EFANNKEF-QEASEKGYPVATPQKSKKAK 367 A++ +L +++ F N++ F Q+ + G A+ S+ K Sbjct: 283 AVSGMLTELQERYHRFRNDEAFLQQVMKDGAEKASAHASRTLK 325 >5DK4-A nrPDB Length = 329 Score = 94.5 bits (233), Expect = 8e-20, Method: Composition-based stats. Identities = 62/346 (17%), Positives = 117/346 (33%), Gaps = 49/346 (14%) Query: 41 KLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEV--TVLLADLHAFLDNMKAPLEVVNYRA 98 ++ G P+G G ++ L F++ E + D HA + + P E+ Sbjct: 4 TIFSGIQPSGVITIGNYIGA--LRQFVELQHEYNCYFCIVDQHA-ITVWQDPHELRQNIR 60 Query: 99 KYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVK 158 + + A+ ++ + + + S + + I + Sbjct: 61 R-----LAALYLAVGIDPTQATLFIQSEVPAHAQAAWMLQCIVYIGELERMTQFKEKSAG 115 Query: 159 QVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNP- 217 + A L YP + A D + D G DQ++ L + + P Sbjct: 116 KEAVS-AGLLTYPPLMAADILLYNTDIVPVGEDQKQHIELTRDLAERFNKRYGELFTIPE 174 Query: 218 ---------MVPGLAQGGKMSASDPNSK--IDLLEEPKQVKKKINSAFC-SPGNVEENGL 265 ++ + KMS SDPN K I LL++ K ++KKI SA S G + + Sbjct: 175 ARIPKVGARIMSLVDPTKKMSKSDPNPKAYITLLDDAKTIEKKIKSAVTDSEGTIRYDKE 234 Query: 266 LSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIG 325 + I G S EE++ ++ + K Sbjct: 235 AKPGISNLLNIYSTLSGQ--------------------SIEELERQYEGKGY--GVFKAD 272 Query: 326 VADAINELLEPIRQ---EFANNKEFQEASEKGYPVATPQKSKKAKK 368 +A + E L PI++ + ++E ++G A S+ +K Sbjct: 273 LAQVVIETLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRK 318 >2YY5-A nrPDB Length = 348 Score = 93.7 bits (231), Expect = 1e-19, Method: Composition-based stats. Identities = 60/319 (18%), Positives = 106/319 (33%), Gaps = 38/319 (11%) Query: 41 KLYWGTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAK 99 + G +G+ H G ++ M L + + C++ V +ADLH+ + + K Sbjct: 6 RALTGIQASGKQHLGNYLGVMQSLIELQEQ-CQLFVFVADLHSITVDFQP------QALK 58 Query: 100 YYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQ 159 + L ++ + +K + S + SN+ + A +Q Sbjct: 59 QNNFDLVRTLLAVGLDPQKACLFLQSDLLEHSMMGYLMMVQSNLGELQRMTQFKAKKAEQ 118 Query: 160 VANPL------LSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAH 213 NP L YP + A D D G DQ++ L + + K + Sbjct: 119 TRNPNGTLNIPTGLLTYPALMAGDILLYQPDIVPVGNDQKQHLELTRDLAQRIQKKFKLK 178 Query: 214 LMNP----------MVPGLAQGGKMSASDPNSK--IDLLEEPKQVKKKINSAFCSPGNVE 261 L P ++ KMS S N I L + + V KKI A Sbjct: 179 LRLPQFVQNKDTNRIMDLFDPTKKMSKSSKNQNGVIYLDDPKEVVVKKIRQATTD----- 233 Query: 262 ENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPD 321 SF + A + E +T + +++ F + D Sbjct: 234 -----SFNKIRFASKTQPGVTNMLTILKALLKEPVNQSLTNQLGNDLEAYFSTKSY--LD 286 Query: 322 LKIGVADAINELLEPIRQE 340 LK + +A LL I+++ Sbjct: 287 LKNALTEATVNLLVNIQRK 305 >6DFU-A nrPDB Length = 337 Score = 93.3 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 59/340 (17%), Positives = 111/340 (32%), Gaps = 39/340 (11%) Query: 42 LYWGTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKY 100 ++ G P+G G ++ + + E + DLHA + + Sbjct: 9 VFSGVQPSGELTIGNYLGALRNWVKMQE-DYECIFCVVDLHAI------TVRQDPVALRK 61 Query: 101 YELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQV 160 L + A+ + + K V S + + + + + + Sbjct: 62 ATLDVLALYLACGIDPNKSTIFVQSHVPEHTQLSWVLNCYTYFGEMSRMTQFKDKSARYA 121 Query: 161 ANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNP-MV 219 N + YP++ A D G DQ++ + + P + Sbjct: 122 ENINVGLFDYPVLMAADILLYQAKSVPVGDDQKQHLEITRDIANRFNALYGNIFTIPEIF 181 Query: 220 PGLAQ---------GGKMSASDP--NSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSF 268 G A KMS SD N+ + LLE+PK V KKI A E ++ + Sbjct: 182 IGKAGARIMSLQDPEKKMSKSDDNRNNVVTLLEDPKSVAKKIKRAVTDSD---EPPVVRY 238 Query: 269 VQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVAD 328 A + L + D+P +++ F E K+ LK VAD Sbjct: 239 DVQNKAGVSNL---LDILSAVTDKP-----------IADLEKEF-EGKMY-GHLKTAVAD 282 Query: 329 AINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKAKK 368 ++ LL +++ F + + + + KA++ Sbjct: 283 EVSTLLASLQERFHQYRNDETLLDNILRQGAEKARAKAQE 322 >3SZ3-A nrPDB Length = 341 Score = 92.5 bits (228), Expect = 3e-19, Method: Composition-based stats. Identities = 65/338 (19%), Positives = 116/338 (34%), Gaps = 41/338 (12%) Query: 45 GTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYEL 103 G P+G G ++ + + + + DLHA ++ + ++ L Sbjct: 12 GVQPSGELSIGNYLGALRQWQQMQD-DYDCQYCVVDLHAI--TVRQDPQALHEA----TL 64 Query: 104 TIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANP 163 AI ++ V +K V S + + + + + + + Sbjct: 65 DALAICLAVGVDPKKSTLFVQSHVPEHAQLGWVLNCYTQMGELSRMTQFKDKSARYANDV 124 Query: 164 LLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLG--YKKRAHLMN---PM 218 YP++ A D G DQ++ LA + Y + P Sbjct: 125 NAGLFGYPVLMAADILLYGAHQVPVGSDQKQHLELARDIATRFNNIYSPEQPIFTIPEPY 184 Query: 219 VPGL--------AQGGKMSASDPNSK--IDLLEEPKQVKKKINSAFCSPGNVEENGLLSF 268 +P + KMS SD N K I LLE+PK + KKIN A E +++ Sbjct: 185 IPTVNARVMSLQDATKKMSKSDDNRKNVITLLEDPKSIIKKINKAQTDA---ETPPRIAY 241 Query: 269 VQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVAD 328 A I L + T K+F E++ + ++ P K V + Sbjct: 242 DVENKAGIANLMGLYSA--------------ATGKTFAEIEAQYAGVEMYGP-FKKDVGE 286 Query: 329 AINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKA 366 A+ +LEP++ E+ + +E + S KA Sbjct: 287 AVVAMLEPVQAEYQRIRNDREYLNSVMRDGAEKASAKA 324 >5EKD-A nrPDB Length = 343 Score = 92.2 bits (227), Expect = 4e-19, Method: Composition-based stats. Identities = 61/339 (17%), Positives = 116/339 (34%), Gaps = 41/339 (12%) Query: 41 KLYWGTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAK 99 +++ G PTG H G ++ + V + DLH+ + + Sbjct: 19 RVFSGIQPTGILHLGNYLGAIESWVRLQDEYDSVLYSIVDLHSI------TVPQDPAVLR 72 Query: 100 YYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQ 159 L + A+L + + EK S + + + + + A KQ Sbjct: 73 QSILDMTAVLLACGINPEKSILFQQSQVSEHTQLSWILSCMVRLPRLQHLHQWKAKTTKQ 132 Query: 160 VANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLP----SLG--YKKRAH 213 + + L YP++QA D G DQ + L ++ G + Sbjct: 133 KHDGTVGLLTYPVLQAADILLYKSTHVPVGEDQVQHMELVQDLAQGFNKKYGEFFPVPES 192 Query: 214 LMNPM--VPGL-AQGGKMSASDPN--SKIDLLEEPKQVKKKINSAFCS-PGNVEENGLLS 267 ++ M V L KMS SDP+ + + + + P+++ +K A V + Sbjct: 193 ILTSMKKVKSLRDPSAKMSKSDPDKLATVRITDSPEEIVQKFRKAVTDFTSEVTYDP--- 249 Query: 268 FVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVA 327 G + +T S EE+ + ++ K+ VA Sbjct: 250 -------------AGRAGVSNIVAVHAA----VTGLSVEEVVR--RSAGMNTARYKLAVA 290 Query: 328 DAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKA 366 DA+ E PI++E K ++ EK + + + + A Sbjct: 291 DAVIEKFAPIKREIEKLKLDKDHLEKVLQIGSAKAKELA 329 >3N9I-A nrPDB Length = 346 Score = 91.4 bits (225), Expect = 6e-19, Method: Composition-based stats. Identities = 62/357 (17%), Positives = 122/357 (34%), Gaps = 44/357 (12%) Query: 24 LNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFV-PMTKLADFLKAGCEVTVLLADLHA 82 ++ ++ V + + ++ G P+G G ++ + + + + DLHA Sbjct: 1 MSEPMVLSKPTVSSKPI-VFSGAQPSGELTIGNYMGALRQWVQMQD-DYDCIYCIVDLHA 58 Query: 83 FLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSN 142 L A+ + + +K V S + + + Sbjct: 59 ITARQDPALLRKRTL------DTLALYLACGIDPKKSTIFVQSHVPEHSQLSWALNCYTY 112 Query: 143 IVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEEN 202 + + + N YP++ A D + G DQ++ L+ + Sbjct: 113 FGELSRMTQFKDKSARYAENINAGLFDYPVLMAADILLYQTNQVPVGEDQKQHLELSRDI 172 Query: 203 LPSLG--YKKRAHLMNPMVP-------GLAQG-GKMSASDP--NSKIDLLEEPKQVKKKI 250 Y + P +P L KMS SD N+ I+LLE+PK V KKI Sbjct: 173 ASRFNNLYGDIFKIPEPFIPKAGARVMSLQDPTKKMSKSDDNRNNVIELLEDPKSVVKKI 232 Query: 251 NSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKL 310 A E L+ + A + L + +T +S E++ Sbjct: 233 KRAMTDSD---EPALIRYDVEKKAGVSNLLDILS--------------GVTGQSIPELEA 275 Query: 311 AFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSKKAK 367 F ++ LK VADA++ +L +++ + +E + + + + KA+ Sbjct: 276 QFT-GQMY-GHLKGAVADAVSGMLSELQERYRTYREDEALLQ----DVMREGAAKAR 326 >3TZL-A nrPDB Length = 322 Score = 81.4 bits (199), Expect = 7e-16, Method: Composition-based stats. Identities = 48/234 (20%), Positives = 90/234 (38%), Gaps = 22/234 (9%) Query: 40 LKLYWGTAPTGRPHCG-YFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRA 98 +++ G P+G H G YF + ++ D + ++ + +A+ HA + + Sbjct: 4 MRVLTGLQPSGDLHIGNYFGAIKQMVDAQEKS-QMFMFIANYHAMTSSQDG------EKL 56 Query: 99 KYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVK 158 K L A S+ + +K F + S + + + + + + A V K Sbjct: 57 KQNSLKAAAAFLSLGIDPQKSVFWLQSDVKEVMELYWILSQFTPMGLLERAHSYKDKVAK 116 Query: 159 QVANPLLSGLI-YPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNP 217 ++ GL YP++ A D D G DQ + +A + + + P Sbjct: 117 GLSAS--HGLFSYPVLMAADILLFDTRIVPVGKDQIQHVEIARDIALKVNNEWGEIFTLP 174 Query: 218 ---------MVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEE 262 +V G KMS S N+ ID+ K +KK+I+S +E+ Sbjct: 175 EARVNEEVAVVVGTDG-AKMSKSYQNT-IDIFSSEKTLKKQISSIVTDSTALED 226 >6MTK-A nrPDB Length = 329 Score = 76.4 bits (186), Expect = 2e-14, Method: Composition-based stats. Identities = 57/314 (18%), Positives = 99/314 (31%), Gaps = 29/314 (9%) Query: 40 LKLYWGTAPTGRPHCGYFV--PMTKLADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYR 97 +++ G TG PH G + + + K + +A+LH L + Sbjct: 9 MRILTGIQATGTPHLGNLLGAIIPAIELAKKPENDSLFFIANLH--------TLTQIKDA 60 Query: 98 A--KYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGAD 155 A + I A + + EK F S T + T + + D Sbjct: 61 AQLRQNTYEIAAAWLACGLDTEKTIFYRQSDIPETCELTWYLDCFFPFQRL-TLAHSFKD 119 Query: 156 VVKQVANPLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYK------ 209 ++ + YP++ A D D + G DQ + + + + Sbjct: 120 KADRLQDVNAGLFNYPILMAADILLYDAEVVPVGKDQLQHLEITRDVAEKFNRQMGEVFV 179 Query: 210 ---KRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLL 266 VPG KMS S N I++ K++KK+I S ++EE Sbjct: 180 LPGAEIQESTKYVPGTDG-HKMSKSRGN-IINIFLPEKELKKQIMSIESDSKSLEEPKDP 237 Query: 267 SFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITY-KSFEEMKLAFKEEKLSPPDLKIG 325 + I + R + G Y + E+ E +L Sbjct: 238 ETDKTFII----YALIATPEQTEALRQKYLAGNFGYGHAKTELLNLILERFAKERELFSY 293 Query: 326 VADAINELLEPIRQ 339 +NEL E ++Q Sbjct: 294 YMSNLNELEEKLQQ 307 >5IHX-A nrPDB Length = 395 Score = 72.1 bits (175), Expect = 4e-13, Method: Composition-based stats. Identities = 54/271 (19%), Positives = 94/271 (34%), Gaps = 51/271 (18%) Query: 14 GLITKNL-QEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGC 71 L + L +V+ + + + +KR + +Y G PT H G+ +P LA G Sbjct: 40 HLEERGLIHDVVGDRDLLHRVFTEKR-VGIYAGVDPTAPSMHVGHMLPFMVLAWGYVWGL 98 Query: 72 EVTVLLADLHAFLDN----MKAPLEVVNYRAKYYELTIKAILRSINVPIEKL-------- 119 VT LL + + + +K +V + K ++ L+ + IE+ Sbjct: 99 PVTFLLGGATSRVGDPTGRLKGREQVHSSVRKANMASMHMQLKKLGASIERYGEKHGYKR 158 Query: 120 -----KFVVGSSYQLTPDYTMDI-------FRLSNIVSQNDAKRAGADVVKQVANPLLSG 167 + + ++ +++ R+ ++ ++ K + + Sbjct: 159 QMIWRRTLTNNNVWWNKTPLLEVLRDLGAYIRIGPMLGRDTVKNRME----RGDGMSFAE 214 Query: 168 LIYPLMQALD---EQFLDVDCQFGGVDQ--------------RKIFVLAEENLP-SLGYK 209 YPLMQA D Q GG DQ K VL E+N P S Sbjct: 215 FTYPLMQAWDWWMLFKNGCQVQVGGSDQYGNILFGVGAVKTISKNTVLQEDNNPLSDDLD 274 Query: 210 KRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 K P++ + G K S N I L Sbjct: 275 KPIGFTTPLLTT-SSGEKFGKSAGN-AIWLD 303 >2JAN-A nrPDB Length = 432 Score = 71.7 bits (174), Expect = 5e-13, Method: Composition-based stats. Identities = 47/221 (21%), Positives = 78/221 (35%), Gaps = 17/221 (7%) Query: 34 EVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKA--- 89 E Q+ + +Y G PT H G+ VP+ L F +AG VL + + + Sbjct: 27 EAQRGPMTVYAGFDPTAPSLHAGHLVPLLTLRRFQRAGHRPIVLAGGATGMIGDPRDVGE 86 Query: 90 -PLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDY--TMDIFRLSNIVSQ 146 L + A++ E + R ++ + +V ++ + T + + S Sbjct: 87 RSLNEADTVAEWTERIRGQLERFVDFDDSPMGAIVENNLEWTGSLSAIEFLRDIGKHFSV 146 Query: 147 NDAKRAGADVVKQVANPLLS--GLIYPLMQALDEQFL----DVDCQFGGVDQRKIFVLA- 199 N A + +++A +S Y L+QA D L Q GG DQ + Sbjct: 147 N-VMLARDTIRRRLAGEGISYTEFSYLLLQANDYVELHRRHGCTLQIGGADQWGNIIAGV 205 Query: 200 EENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 LG A L P+V K S + L Sbjct: 206 RLVRQKLGATVHA-LTVPLVTAADG-TKFGKSTGGGSLWLD 244 >6HB6-A nrPDB Length = 424 Score = 70.6 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 41/255 (16%), Positives = 88/255 (34%), Gaps = 23/255 (9%) Query: 1 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVP 59 M+S+ + + GL+ + E + + + L + LY G PT H G+ VP Sbjct: 1 MASSNLIKQLQERGLVAQVTDE----EALAERLAQG--PIALYCGFDPTADSLHLGHLVP 54 Query: 60 MTKLADFLKAGCEVTVLLADLHAFLDN-----MKAPLEVVNYRAKYYELTIKAILRSINV 114 + L F +AG + L+ + + + L ++ + K + ++ Sbjct: 55 LLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDF 114 Query: 115 PIEKLKFVVGSSYQLTPD-----YTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLI 169 + + ++Y + + DI + ++ + + + ++ + Sbjct: 115 DCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFS 174 Query: 170 YPLMQALDEQFL----DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQG 225 Y L+Q D L V Q GG DQ + L + L P++ Sbjct: 175 YNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADG- 233 Query: 226 GKMSASDPNSKIDLL 240 K ++ + L Sbjct: 234 TKFGKTEGG-AVWLD 247 >1X8X-A nrPDB Length = 322 Score = 70.6 bits (171), Expect = 1e-12, Method: Composition-based stats. Identities = 41/255 (16%), Positives = 88/255 (34%), Gaps = 23/255 (9%) Query: 1 MSSAATVDPNEAFGLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVP 59 M+S+ + + GL+ + E + + + L + LY G PT H G+ VP Sbjct: 1 MASSNLIKQLQERGLVAQVTDE----EALAERLAQG--PIALYCGFDPTADSLHLGHLVP 54 Query: 60 MTKLADFLKAGCEVTVLLADLHAFLDN-----MKAPLEVVNYRAKYYELTIKAILRSINV 114 + L F +AG + L+ + + + L ++ + K + ++ Sbjct: 55 LLCLKRFQQAGHKPVALVGGATGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDF 114 Query: 115 PIEKLKFVVGSSYQLTPD-----YTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLI 169 + + ++Y + + DI + ++ + + + ++ + Sbjct: 115 DCGENSAIAANNYDWFGNMNVLTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFS 174 Query: 170 YPLMQALDEQFL----DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQG 225 Y L+Q D L V Q GG DQ + L + L P++ Sbjct: 175 YNLLQGYDFACLNKQYGVVLQIGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADG- 233 Query: 226 GKMSASDPNSKIDLL 240 K ++ + L Sbjct: 234 TKFGKTEGG-AVWLD 247 >3TS1-A nrPDB Length = 419 Score = 69.8 bits (169), Expect = 2e-12, Method: Composition-based stats. Identities = 56/372 (15%), Positives = 112/372 (30%), Gaps = 33/372 (8%) Query: 18 KNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVL 76 + L + L ++R + LY G PT H G+ + + F +AG L Sbjct: 10 RGLVNQTTDEDGLRKLLNEER-VTLYCGFDPTADSLHIGHLATILTMRRFQQAGHRPIAL 68 Query: 77 LADLHAFLDNMKAPLEVVNYRAK-YYELTIKAILRSINVPIE------KLKFVVGSSYQL 129 + + + AK E I + ++ K + Sbjct: 69 VGGATGLIGDPSGKKSERTLNAKETVEAWSARIKEQLGRFLDFEADGNPAKIKNNYDWIG 128 Query: 130 TPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFL----DVDC 185 D + + S N + + + Y ++QA D L Sbjct: 129 PLDVITFLRDVGKHFSVNYMMAKESVQSRIETGISFTEFSYMMLQAYDFLRLYETEGCRL 188 Query: 186 QFGGVDQRKIFVLAEENLPS-LGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPK 244 Q GG DQ E + G + L P+V K ++ + I L +E Sbjct: 189 QIGGSDQWGNITAGLELIRKTKGEARAFGLTIPLVTKADG-TKFGKTESGT-IWLDKEKT 246 Query: 245 QVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKS 304 + + N ++ ++ +++Y +E + + PEK T Sbjct: 247 SPYE----FYQFWINTDDRDVIRYLKYFTFLSKEEIEALE--QELREAPEKRAAQKTLAE 300 Query: 305 --------FEEMKLAFK-EEKLSPPDLKIGVADAINELLEPIRQ--EFANNKEFQEASEK 353 E ++ A + E L D+ A I + + + + E Sbjct: 301 EVTKLVHGEEALRQAIRISEALFSGDIANLTAAEIEQGFKDVPSFVHEGGDVPLVELLVS 360 Query: 354 GYPVATPQKSKK 365 + +++++ Sbjct: 361 AGISPSKRQARE 372 >5TEW-A nrPDB Length = 344 Score = 69.4 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 52/327 (15%), Positives = 102/327 (31%), Gaps = 41/327 (12%) Query: 52 PHCGYFVPMTK--LADFLKAGCEVTVLLADLHAFLDNMKAPLEVVNYRAKYYELTIKAIL 109 PH G +V + + E + LAD H + + + + +A + A Sbjct: 24 PHLGNYVGAIRPAVRAAQNPDTESFLFLADYHGIIKCHEQEMIHQSTQA------VAATW 77 Query: 110 RSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVAN------- 162 + + E+ F S + + ++ N A A V N Sbjct: 78 LACGLDPERTTFYRQSDIPEVMELNWILTCITAKGLMNRAHAYKAAVQANAENGQEDPDF 137 Query: 163 -PLLSGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNP---- 217 + YP++ D + + G DQ + +A + ++ + P Sbjct: 138 GVEMGLFSYPILMTADILMFNANEVPVGRDQIQHVEMARDIAGRFNHRFQELFTLPEVKI 197 Query: 218 -----MVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFC------SPGNVEENGLL 266 ++ GL KMS S N+ I L E K+ +K +N P +E+ L Sbjct: 198 DENVELLVGLDG-RKMSKSYGNT-IPLWENDKKTQKSVNKIITNMKEPGEPKQPDESPLF 255 Query: 267 SFVQYVIAPIQELKFGTNHFE-FFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIG 325 + P + +F + +K E++ + +P ++ Sbjct: 256 EIYKAFSTPSETAEFTQMLADGLAWGEAKKLSAAKINAELAELRERYNALTSNPSQIEEI 315 Query: 326 VA-------DAINELLEPIRQEFANNK 345 + ELL+ +R Sbjct: 316 LQAGAQKARKEARELLDKVRDAVGIRP 342 >1JIJ-A nrPDB Length = 420 Score = 69.0 bits (167), Expect = 3e-12, Method: Composition-based stats. Identities = 56/346 (16%), Positives = 106/346 (30%), Gaps = 41/346 (11%) Query: 26 PQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADLHAFL 84 Q I+D+L ++ + LY G PT H G+ +P L F + G VL+ + Sbjct: 21 EQGIEDLLNKEQ--VTLYCGADPTADSLHIGHLLPFLTLRRFQEHGHRPIVLIGGGTGMI 78 Query: 85 DNMKAP-----LEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFR 139 + L+ K E K + + +V + L + R Sbjct: 79 GDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDHGAVLVNNRDWLGQISLISFLR 138 Query: 140 LSNIVSQNDAKRAGADVVKQVANPL-LSGLIYPLMQALDEQFLDVD----CQFGGVDQRK 194 + + ++ + + + Y ++QA+D L+ + Q GG DQ Sbjct: 139 DYGKHVGVNYMLGKDSIQSRLEHGISYTEFTYTILQAIDFGHLNRELNCKIQVGGSDQWG 198 Query: 195 IFVLAEENLPS-LGYKKRAHLMNPMVPGLAQGGKMSASDPN--------------SKIDL 239 E + G L P+V + G K S+ + + Sbjct: 199 NITSGIELMRRMYGQTDAYGLTIPLVTK-SDGKKFGKSESGAVWLDAEKTSPYEFYQFWI 257 Query: 240 LEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRP------ 293 + + V K + + S + + +F Sbjct: 258 NQSDEDVIKFLKYFTFLGKEEIDRLEQSKNEAPHLREAQKTLAEEVTKFIHGEDALNDAI 317 Query: 294 ----EKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLE 335 F G + S +E+K FK+ + L + + L+E Sbjct: 318 RISQALFSGDLKSLSAKELKDGFKD--VPQVTLSNDTTNIVEVLIE 361 >6N0W-A nrPDB Length = 480 Score = 68.7 bits (166), Expect = 4e-12, Method: Composition-based stats. Identities = 36/219 (16%), Positives = 62/219 (28%), Gaps = 21/219 (9%) Query: 41 KLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLDNMKA--------PL 91 Y G PT H G +P+ LA F + G + L+ + + Sbjct: 39 TAYIGFDPTADSLHIGSLIPIKILAHFQRHGHKPIALVGGATGMIGDPSGKSAERNLLDE 98 Query: 92 EVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKR 151 E + Y + + L + + V + + + ++ N Sbjct: 99 ETLLYYVDCLKNQLSRFLDFEGDGPNRAELVNNYDWMKNVTFLDFAKNIGKHITVN-YMM 157 Query: 152 AGADVVKQVANPL------LSGLIYPLMQALDEQFL----DVDCQFGGVDQRKIFVLAEE 201 A V K+ + + Y L+Q D L V Q GG DQ E Sbjct: 158 AKDSVKKRFSGEDGADGMSFTEFTYQLLQGYDYLHLYKEKGVKLQMGGSDQWGNITTGTE 217 Query: 202 NLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLL 240 + + L ++ K S+ L Sbjct: 218 LIRRKAQGEAFALTTKLITKADG-SKFGKSESGENYWLD 255 >4OUD-B nrPDB Length = 394 Score = 68.3 bits (165), Expect = 6e-12, Method: Composition-based stats. Identities = 35/220 (15%), Positives = 75/220 (34%), Gaps = 17/220 (7%) Query: 22 EVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADL 80 +V + + + + L + LY G PT H G+ VP+ L F +AG + L+ Sbjct: 19 QVTDEEALAERLAQG--PIALYCGFDPTADSLHAGHLVPLLCLKRFQQAGHKPVALVGGA 76 Query: 81 HAFLDN-----MKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPD--- 132 + + + L ++ + K + ++ + + ++Y + Sbjct: 77 TGLIGDPSFKAAERKLNTEETVQEWVDKIRKQVAPFLDFDCGENSAIAANNYDWFGNMNV 136 Query: 133 --YTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFL----DVDCQ 186 + DI + ++ + + + ++ + Y L+Q D L V Q Sbjct: 137 LTFLRDIGKHFSVNQMINKEAVKQRLNREDQGISFTEFSYNLLQGYDFACLNKQYGVVLQ 196 Query: 187 FGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGG 226 GG DQ + L + L P++ Sbjct: 197 IGGSDQWGNITSGIDLTRRLHQNQVFGLTVPLITKADGTK 236 >1TYB-E nrPDB Length = 319 Score = 67.1 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 49/299 (16%), Positives = 90/299 (30%), Gaps = 22/299 (7%) Query: 18 KNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVL 76 + L + L ++R + LY G PT H G+ + + F +AG L Sbjct: 10 RGLVNQTTDEDGLRKLLNEER-VTLYCGFDPTADSLHIGHLAGILTMRRFQQAGHRPIAL 68 Query: 77 LADLHAFLDNMKAPLEVVNYRAK-YYELTIKAILRSIN--VPIE----KLKFVVGSSYQL 129 + + + AK E I + + E K + Sbjct: 69 VGGATGLIGDPSGKKSERTLNAKETVEAWSARIKEQLGRFLDFEADGNPAKIKNNYDWIG 128 Query: 130 TPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFL----DVDC 185 D + + S N + + + Y ++QA D L Sbjct: 129 PLDVITFLRDVGKHFSVNYMMAKESVQSRIETGISFTEFSYMMLQAYDFLRLYETEGCRL 188 Query: 186 QFGGVDQRKIFVLAEENLPS-LGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPK 244 Q GG DQ E + G + L P+V K ++ + I L +E Sbjct: 189 QIGGSDQWGNITAGLELIRKTKGEARAFGLTIPLVTKADG-TKFGKTESGT-IWLDKEKT 246 Query: 245 QVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYK 303 + + N ++ ++ +++Y +E + + PEK T Sbjct: 247 SPYE----FYQFWINTDDRDVIRYLKYFTFLSKEEIEALE--QELREAPEKRAAQKTLA 299 >3U1V-A nrPDB Length = 338 Score = 66.7 bits (161), Expect = 1e-11, Method: Composition-based stats. Identities = 58/339 (17%), Positives = 110/339 (32%), Gaps = 49/339 (14%) Query: 48 PTGRPHCGYFVPMTKLADFLKAGCEV--TVLLADLHAFLDNMKAPLEVVNYRAKYYELTI 105 PTG G ++ L F++ E +AD A + + P E+ + + Sbjct: 10 PTGVITIGRYIGA--LRQFVELQHEYNCYFCIADQSA-ITVWQDPHELRQNIRR-----L 61 Query: 106 KAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLL 165 A+ ++ + + + S + + I + A Sbjct: 62 AALYLAVGIDPTQATLFIASEVPAHAQAAWMLQCIVYIGELERMTLFKELSAGKEAVS-A 120 Query: 166 SGLIYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNP-------- 217 L +P + A + D G ++++ L + + P Sbjct: 121 GLLTHPPIYAAMILLYNTDIVPVGEYGKQLYELTRDLAERFNKRYGELFTIPEARIPKVG 180 Query: 218 -MVPGLAQGGK-MSASDPNSK--IDLLEEPKQVKKKINSAFC-SPGNVEENGLLSFVQYV 272 + L K M SDPN K I LL++ K ++KKI SA S G + + Sbjct: 181 ARIMSLVDPTKSMYQSDPNPKAYITLLDDAKTIEKKIKSAVTDSEGTIRYDKEAKPGISN 240 Query: 273 IAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINE 332 + I G S EE++ ++ + K +A + E Sbjct: 241 LLNIYSTLSGQ--------------------SIEELERQYEGKGY--GVFKADLAQVVIE 278 Query: 333 LLEPIRQ---EFANNKEFQEASEKGYPVATPQKSKKAKK 368 L PI++ + ++E ++G A S+ +K Sbjct: 279 TLRPIQERYHHWMESEELDRVLDEGAEKANRVASEMVRK 317 >5IJX-A nrPDB Length = 384 Score = 66.7 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 45/259 (17%), Positives = 78/259 (30%), Gaps = 44/259 (16%) Query: 23 VLNPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADLH 81 V+ + D L +KR + Y G PT H G+ +P L G + L+ Sbjct: 50 VVGQRDALDKLITRKR-VGFYAGVDPTAPSLHIGHMLPFMILGWAYVHGLKAVFLIGGST 108 Query: 82 AFLDNMKAPLE----VVNYRAKYYELTIKAILRSINVPIEKL--------KFVVGSSYQL 129 A + + LE + + I L+ + EK ++ + + Sbjct: 109 AKIGDPTGRLEGRPLMDGATRRANIANIHLQLKRLGFSFEKYGRKHGFEWEWAWRRALEN 168 Query: 130 TPDYTMDIFRLSNIVSQNDAKRAGADVVKQV--------ANPLLSGLIYPLMQALDEQFL 181 + + + R G + + ++ YP+MQ D +L Sbjct: 169 NNTWWNKQSLKEVMEVLGTSLRLGPMLGRDYVKSRLASGEGMSIAEFCYPIMQGWDFWYL 228 Query: 182 ---DVDCQFGGVDQRKIFVLA-------------EENLPSLGYKK----RAHLMNPMVPG 221 V Q GG DQ + E P + P++ Sbjct: 229 FQRKVQVQVGGSDQYGNILFGMDAIKGILKANPESEWAPKKDEDPDLANPYGITTPLLTT 288 Query: 222 LAQGGKMSASDPNSKIDLL 240 A G K+ S N + L Sbjct: 289 -ASGEKIGKSAGN-AVWLD 305 >6OTJ-A nrPDB Length = 439 Score = 66.0 bits (159), Expect = 3e-11, Method: Composition-based stats. Identities = 38/221 (17%), Positives = 75/221 (33%), Gaps = 17/221 (7%) Query: 27 QIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLD 85 + + +L QK + LY G PT H G+ +P+ L F +AG L+ + Sbjct: 28 EALDALLNEQK--IALYCGFDPTADSLHIGHLLPVLALRRFQQAGHTPIALVGGATGMIG 85 Query: 86 N-----MKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTP----DYTMD 136 + + L A + + ++ + ++ D+ D Sbjct: 86 DPSFKAAERSLNSAETVAGWVGSIRSQLTPFLSFEGGNAAIMANNADWFGSMNCLDFLRD 145 Query: 137 IFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFL----DVDCQFGGVDQ 192 I + ++ + + + + + A + Y L+Q D L + GG DQ Sbjct: 146 IGKHFSVNAMLNKESVKQRIDRDGAGISFTEFAYSLLQGYDFAELNKRHGAVLEIGGSDQ 205 Query: 193 RKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDP 233 + L K+ L P+V + G K ++ Sbjct: 206 WGNITAGIDLTRRLNQKQVFGLTLPLVTK-SDGTKFGKTEG 245 >2RKJ-A nrPDB Length = 392 Score = 65.2 bits (157), Expect = 5e-11, Method: Composition-based stats. Identities = 41/262 (15%), Positives = 84/262 (32%), Gaps = 54/262 (20%) Query: 25 NPQIIKDVLEVQKRHLKLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLADLHAF 83 + I +++ R + Y G PT H G+ +P+ L G + L+ A Sbjct: 52 TKEHIAELMRT--RRIGAYVGIDPTAPSLHVGHLLPLMPLFWMYLEGYKAFTLIGGSTAK 109 Query: 84 LDNMKA---------------PLEVVNYRAKYYELTIKAILRSINVPIE--KLKFVVGSS 126 + + + ++Y+ K + +R+ + + + +V ++ Sbjct: 110 IGDPTGRLKSRDHLSSSDATMNMTKIHYQLKKLWENVDTQMRARGYEADWARKRGIVNNN 169 Query: 127 YQLTPDYTMDI-------FRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQ 179 + +++ R+ ++S++ K Q + YP+MQ D Sbjct: 170 HWWNKQPMLEVLRRVGHALRIGPMLSRDTVKNKMT----QGDGVSFAEFTYPIMQGWDWF 225 Query: 180 FL----DVDCQFGGVDQRKIFVLAEENLPSLGYKKR-----------------AHLMNPM 218 L V Q GG DQ + E + + + P+ Sbjct: 226 ELFYQQGVQMQIGGSDQYGNIISGLEVVKAARESEPDPQERKYVTPKTALDECVGFTVPL 285 Query: 219 VPGLAQGGKMSASDPNSKIDLL 240 + + G K S N I L Sbjct: 286 LTD-SSGAKFGKSAGN-AIWLD 305 >2PID-A nrPDB Length = 356 Score = 64.8 bits (156), Expect = 7e-11, Method: Composition-based stats. Identities = 40/237 (16%), Positives = 79/237 (33%), Gaps = 26/237 (10%) Query: 22 EVLNPQIIKDVLEVQKRHL--KLYWGTAPTGR-PHCGYFVPMTKLADFLKAGCEVTVLLA 78 E + ++ + +Y G PT H G+ + + L +AG V L+ Sbjct: 27 ETGTKIELPELFDRGTASFPQTIYCGFDPTADSLHVGHLLALLGLFHLQRAGHNVIALVG 86 Query: 79 DLHAFLDNMKA--------PLEVVNYRAKYYELTIKAI------LRSINVPIEKLKFVVG 124 A L + E V A+ L ++A+ L + + Sbjct: 87 GATARLGDPSGRTKEREALETERVRANARALRLGLEALAANHQQLFTDGRSWGSFTVLDN 146 Query: 125 SSYQLTPDYTMDIFRL---SNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFL 181 S++ + + + + ++++ +K L+ Y ++QA D +L Sbjct: 147 SAWYQKQHLVDFLAAVGGHFRMGTLL-SRQSVQLRLKSPEGMSLAEFFYQVLQAYDFYYL 205 Query: 182 ----DVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPN 234 Q GG DQ + E + L + + P++ G K+ S N Sbjct: 206 FQRYGCRVQLGGSDQLGNIMSGYEFINKLTGEDVFGITVPLITS-TTGAKLGKSAGN 261 >3HZR-A nrPDB Length = 386 Score = 63.6 bits (153), Expect = 1e-10, Method: Composition-based stats. Identities = 52/355 (14%), Positives = 113/355 (31%), Gaps = 48/355 (13%) Query: 24 LNPQIIKDVLE--VQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKA-GCEVTVLLADL 80 L + + L+ K+ ++ P ++ + A +V + + D Sbjct: 65 LAEKSLDKFLDDVEAKKPTFIFIQKYPQKEVALEEYITLEFARYLQDAFNIQVIIQILDD 124 Query: 81 HAFLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRL 140 L+ +N +K +K IL + K + + YQ Y ++R Sbjct: 125 IKVLNREA----TINEASKMSNDLMKYIL---AFGFNEDKTFIYTDYQ----YFGKMYRT 173 Query: 141 SNIVSQNDAKRAGADVVKQVANPLLSGLIYPLMQALDEQFLDVD---------CQFGGVD 191 ++V + A + + L P + + Sbjct: 174 ISLVEKATAYNVVQPFFNFEYSDNIGKLASPSIMTASMFSQSYSHFFSSPARCLVLDSIK 233 Query: 192 QRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKIN 251 + + ++ +L + + L + MVP L+ K ++ I L + KQV++KIN Sbjct: 234 NVQFHSIIDQIATTLNFIQPTVLFHKMVPLLSGVTKFDIPSDHNSILLSDNAKQVERKIN 293 Query: 252 SAFCSPG--NVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMK 309 S G EE+ L + Q L ++ ++++ Sbjct: 294 KLAFSGGRNTTEEHKKLGGQCDIDVSFQLLNIFSSDN----------------AQVKDVE 337 Query: 310 LAFKEEKLSPPDLKIGVADAINELLEPIRQEFANNKEFQEASEKGYPVATPQKSK 364 + + +L +LK V+ ++ + ++ Y A K+K Sbjct: 338 EKYSKGELLSGELKKIVSASM-------KDFIVAYDAKKKPITTAYLKAYISKTK 385 >5KPG-A nrPDB Length = 397 Score = 34.8 bits (78), Expect = 0.070, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 31/68 (45%), Gaps = 1/68 (1%) Query: 14 GLITKNLQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEV 73 LI + ++ + I+ ++++Q + +L WG PT V + ++ EV Sbjct: 54 NLIKRIEHGEVSDEEIRGMMKIQVQK-RLKWGYKPTHEQQLAQLVTFAQSLKGMEMAEEV 112 Query: 74 TVLLADLH 81 L A+L+ Sbjct: 113 DTLDAELY 120 >3TQO-A nrPDB Length = 462 Score = 31.7 bits (70), Expect = 0.58, Method: Composition-based stats. Identities = 42/236 (17%), Positives = 74/236 (31%), Gaps = 23/236 (9%) Query: 174 QALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAH---LMNPMVPGLAQGGKMSA 230 + D GG+D + E G +K + ++ KMS Sbjct: 215 MSSSILGQPFDIHGGGLDLKFPHHENEIAQSEAGEEKPFVKLWMHAGLLE--INKEKMSK 272 Query: 231 SDPNSKIDLLEEPKQVKKKINSAFCSPGNVE----------ENGLLSFVQYVIAPIQELK 280 S N I + E K+ ++ F G+ ENG L+ ++ +A Sbjct: 273 SLGN-IISIREALKESDVEVLRYFLLSGHYRNPLSYSKENLENGRLALERFYLALRGLPV 331 Query: 281 FGTNHFEFFIDR-----PEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAINELLE 335 + DR + F PI + EM + + K V A + L Sbjct: 332 VNHEKTSSYTDRFYEAMDDDFNTPIAFALLFEMVREINRFRDNNQIEKAAVLAAELKCLG 391 Query: 336 PIRQEFANNKEFQEASEKGYPVATPQKSKKAKKPKNKGTKYPGATKTNEIATKLEE 391 I + E + + A Q+ KK +N+ ++I +L + Sbjct: 392 NIFGLLQYSPE--QFLQGAKKEADVQEIKKLIDQRNEARAKKDWKTADQIRDQLTD 445 >5JTA-A nrPDB Length = 751 Score = 31.7 bits (70), Expect = 0.60, Method: Composition-based stats. Identities = 45/289 (15%), Positives = 82/289 (28%), Gaps = 67/289 (23%) Query: 113 NVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVSQNDAKRAGADVVKQVANPLLSGLIYPL 172 P + K ++ TM +F + + + + Y Sbjct: 37 GPPTDPRKQKQAKPAKINRTRTMSVFDNVSPFKKTGFGKLQQTRRGSEDDT------YSS 90 Query: 173 MQALDEQFLD-----VDCQFGGVDQRKIFVLAEE----------NLPSLGYKKRAHLMNP 217 Q F++ ++ D K + + E S GYK Sbjct: 91 SQGNRRFFIEDVDKTLNELLAAEDTDKNYQITIEDTGPKVLKVGTANSYGYKHINIRGTY 150 Query: 218 MVPGLAQGGKMSASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGL--------LSFV 269 M+ L Q ++ S +I L E + EN + F Sbjct: 151 MLSNLLQELTIAKSFGRHQIFLDEA----------------RINENPVNRLSRLINTQFW 194 Query: 270 QYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSF---EEMKLAFKEEKLSPPDLKIGV 326 + + G + ID P P Y + E+ + + ++ P LK+ V Sbjct: 195 NSLTRRVDLNNVGEIAKDTKIDTPGA-KNPRIYVPYDCPEQYEFYVQASQMHP-SLKLEV 252 Query: 327 --------ADAINELLE-------PIRQEFANNKEFQEASEKGYPVATP 360 A+ + + + + + F N E + GYP A P Sbjct: 253 EYLPKKITAEYVKSVNDTPGLLALAMEEHF--NPSTGEKTLIGYPYAVP 299 >2HZ7-A nrPDB Length = 851 Score = 31.3 bits (69), Expect = 0.78, Method: Composition-based stats. Identities = 16/125 (12%), Positives = 40/125 (32%), Gaps = 20/125 (16%) Query: 24 LNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGY-FVPMTKLADFLKAGCEVTVLLADLHA 82 + I +D+ + + + P+G H G+ F + + G + + Sbjct: 51 ITEIIERDLEAGKYPRVVTRFPPDPSGYAHLGHVFASLLDFNTARQYGGQFNL------- 103 Query: 83 FLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSN 142 +D+ L + Y +I L+ + + G + DY + + Sbjct: 104 RMDDTNPEL-----ARQEYVDSIADDLKWLGLD-------WGEHFYYASDYFDRYYAYAE 151 Query: 143 IVSQN 147 + + Sbjct: 152 QLIRQ 156 >4H3S-A nrPDB Length = 817 Score = 31.3 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 22/122 (18%), Positives = 47/122 (38%), Gaps = 19/122 (15%) Query: 26 PQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLADLHAFLD 85 P+++K+ LEV ++ + P G H G+ + V A H Sbjct: 238 PELMKEHLEVTGGKVRTRFPPEPNGYLHIGHSKAIM-----------VNFGYAKYHNGTC 286 Query: 86 NMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLTPDYTMDIFRLSNIVS 145 ++ A Y +IK ++ + K+ + + DY +++RL+ ++ Sbjct: 287 YLRFDDTNPEKEAPEYFESIKRMVSWLGFKPWKITY--------SSDYFDELYRLAEVLI 338 Query: 146 QN 147 +N Sbjct: 339 KN 340 >1V33-A nrPDB Length = 366 Score = 30.9 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 29/133 (21%), Positives = 50/133 (37%), Gaps = 20/133 (15%) Query: 20 LQEVLNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMTKLADFLKAGCEVTVLLAD 79 E+ + + + +L ++ L G R GYF+ KL + AG ++ Sbjct: 196 ASEIEDVEEFRKLLLNKRGWFVLNHGYPRAFRLRFGYFILRIKLPHLINAGIRKSI---- 251 Query: 80 LHAFLDNMKAPLEVVNYRAKYYELTIKAILRS--INVPIEKLKFVVGSSYQLTPDY---- 133 + K + Y E KAIL + V IE L + S + + Y Sbjct: 252 -AKSILKSKEEI--------YEEFVRKAILAAFPQGVGIESLAKLFALSTRFSKSYFDGR 302 Query: 134 -TMDIFRLSNIVS 145 T+D+ R+ + S Sbjct: 303 VTVDLKRILRLPS 315 >2PQ6-A nrPDB Length = 482 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 15/81 (18%), Positives = 30/81 (37%), Gaps = 2/81 (2%) Query: 263 NGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDL 322 N L + + + F + E+ R K GP + F + + L+P + Sbjct: 23 NPLFKLAKLLHLRGFHITFV--NTEYNHKRLLKSRGPKAFDGFTDFNFESIPDGLTPMEG 80 Query: 323 KIGVADAINELLEPIRQEFAN 343 V+ + L + +R+ F Sbjct: 81 DGDVSQDVPTLCQSVRKNFLK 101 >5ZDO-A nrPDB Length = 548 Score = 30.1 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 32/108 (29%), Gaps = 15/108 (13%) Query: 24 LNPQIIKDVLEVQKRHLKLYWGTAPTGRPHCGYFVPMT-KLADFLKAGCEVTVLLADLHA 82 + + +D+ E + L + P G H G+ + G E + Sbjct: 9 ITELVERDLKEGKYAKLVTRFPPEPNGYLHIGHARSIVLNFGLAQDYGGECNLRF----- 63 Query: 83 FLDNMKAPLEVVNYRAKYYELTIKAILRSINVPIEKLKFVVGSSYQLT 130 D+ E Y I+ +R + + + S Y T Sbjct: 64 --DDTNPETEKEE-----YARAIEEDVRWLG--FRPTRVLYASDYFET 102 >1IRX-A nrPDB Length = 523 Score = 30.1 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 21/66 (31%), Gaps = 5/66 (7%) Query: 180 FLDVDCQFGGVDQ----RKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSASDPNS 235 VD + G D E G + LM V Q GKMS S N Sbjct: 228 HFGVDFEPAGKDHLVAGSSYDTGKEIIKEVYGKEAPLSLMYEFVGIKGQKGKMSGSKGN- 286 Query: 236 KIDLLE 241 I L + Sbjct: 287 VILLSD 292 >4ANW-A nrPDB Length = 980 Score = 30.1 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 14/56 (25%), Positives = 24/56 (42%), Gaps = 2/56 (3%) Query: 177 DEQFLDVDCQFGG--VDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKMSA 230 D +++ G D +K F+ E G+ + + +V G+ QG K SA Sbjct: 909 DIEYIRDALTVGKNEEDAKKYFLDQIEVCRDKGWTVQFNWFLHLVLGIKQGEKHSA 964 >4L0O-H nrPDB Length = 388 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 45/131 (34%), Gaps = 12/131 (9%) Query: 169 IYPLMQALDEQFLDVDCQFGGVDQRKIFVLAEENLPSLGYKKRAHLMNPMVPGLAQGGKM 228 ++ L+Q+ D L D +GG F L + L G + ++Q K Sbjct: 81 VFSLLQSGDHVLLGDDV-YGGT-----FRLFNQVLVKNGLSCTIIDTS----DISQIKK- 129 Query: 229 SASDPNSKIDLLEEPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEF 288 A PN+K LE P KI +++GLL+ V A + Sbjct: 130 -AIKPNTKALYLETPSNPLLKITDLAQCASVAKDHGLLTIVDNTFATPYYQNPLLLGADI 188 Query: 289 FIDRPEKFGGP 299 K+ G Sbjct: 189 VAHSGTKYLGG 199 >5K0S-A nrPDB Length = 536 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 13/87 (14%), Positives = 26/87 (29%), Gaps = 9/87 (10%) Query: 48 PTGRPHCGY---FVPMTKLADFLKA-GCEVTVLLADLH---AFLDNMKAPLEVVNYRAKY 100 P G+PH G+ + +A F + G +V L L + + A Sbjct: 36 PNGKPHIGHAYELIATDAMARFQRLNGMDVYFLTGTDEHGIKMLQSARKEGITPRDLADR 95 Query: 101 YELTIKAILRSINVPIEKLKFVVGSSY 127 + + + ++ S Sbjct: 96 NTSAFRRMAEVL--NSSNDDYIRTSEE 120 >6A7J-A nrPDB Length = 411 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 29/75 (38%), Gaps = 2/75 (2%) Query: 288 FFIDRPEKFGGPITYKSFEEMKLAFKEEKLSPPDLKIGVADAI--NELLEPIRQEFANNK 345 + R EK I + ++ P DLK A + N + E + + A++ Sbjct: 107 LTVKRVEKLRAGIEALTNASLERLAALPAGEPVDLKAEFAYPLPMNVISELMGVDAADHP 166 Query: 346 EFQEASEKGYPVATP 360 +E EK + TP Sbjct: 167 RLKELFEKFFSTQTP 181 >5L6W-C nrPDB Length = 167 Score = 27.8 bits (60), Expect = 7.5, Method: Composition-based stats. Identities = 24/114 (21%), Positives = 43/114 (37%), Gaps = 11/114 (9%) Query: 242 EPKQVKKKINSAFCSPGNVEENGLLSFVQYVIAPIQELKFGTNHFEFFIDRPEKFGG--- 298 P++VKK+ + ++N +L + ++ + F P+K Sbjct: 26 TPEEVKKRKKAVLFCLSEDKKNIILEEGKEILVGDVGQTVDDPYATFVKMLPDKDCRYAL 85 Query: 299 -PITYKSFEEMKLA----FKEEKLSPPDLKIGVA---DAINELLEPIRQEFANN 344 TY++ E K F + +P K+ A DAI + L I+ E N Sbjct: 86 YDATYETKESKKEDLVFIFWAPESAPLKSKMIYASSKDAIKKKLTGIKHELQAN 139 >4GEW-A nrPDB Length = 362 Score = 27.8 bits (60), Expect = 9.5, Method: Composition-based stats. Identities = 11/25 (44%), Positives = 16/25 (64%) Query: 225 GGKMSASDPNSKIDLLEEPKQVKKK 249 KMS D +I++L+EP+Q K K Sbjct: 15 RQKMSQEDSEVEIEILDEPEQGKLK 39 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.125 0.306 Lambda K H 0.267 0.0384 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,192,372 Number of Sequences: 36641 Number of extensions: 503593 Number of successful extensions: 1810 Number of sequences better than 10.0: 76 Number of HSP's better than 10.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 47 Number of HSP's that attempted gapping in prelim test: 1551 Number of HSP's gapped (non-prelim): 140 length of query: 394 length of database: 10,336,785 effective HSP length: 99 effective length of query: 295 effective length of database: 6,709,326 effective search space: 1979251170 effective search space used: 1979251170 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 60 (27.8 bits)