BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P36368 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1AO5-A nrPDB 489 e-139 1SGF-G nrPDB 358 e-100 1SGF-A nrPDB 347 3e-96 1TON-A nrPDB 297 4e-81 1SPJ-A nrPDB 297 4e-81 4NFE-A nrPDB 283 6e-77 3QUM-P nrPDB 260 4e-70 1GVZ-A nrPDB 233 6e-62 5MS3-A nrPDB 202 9e-53 1NPM-A nrPDB 201 4e-52 3BSQ-A nrPDB 193 8e-50 5ZFH-A nrPDB 191 3e-49 1A0J-A nrPDB 186 8e-48 1UTJ-A nrPDB 184 3e-47 5FXL-A nrPDB 182 1e-46 2PSX-A nrPDB 181 2e-46 1F7Z-A nrPDB 181 2e-46 2BDH-A nrPDB 179 8e-46 4WWY-A nrPDB 179 8e-46 5C67-A nrPDB 177 4e-45 4AN7-A nrPDB 172 2e-43 2EEK-A nrPDB 171 4e-43 2PKA-B nrPDB 169 1e-42 6QHB-A nrPDB 167 4e-42 2TLD-E nrPDB 167 4e-42 1FXY-A nrPDB 160 4e-40 5LPF-A nrPDB 160 7e-40 4GSO-A nrPDB 154 4e-38 1EUF-A nrPDB 150 6e-37 2AIQ-A nrPDB 148 2e-36 3S9B-A nrPDB 146 7e-36 1OP0-A nrPDB 142 1e-34 1FDP-A nrPDB 142 1e-34 4E7N-A nrPDB 140 4e-34 1BQY-A nrPDB 139 1e-33 1ORF-A nrPDB 137 4e-33 3S69-A nrPDB 136 7e-33 1MZD-A nrPDB 135 2e-32 3E0N-B nrPDB 134 5e-32 3DFJ-A nrPDB 133 7e-32 1FI8-A nrPDB 133 8e-32 2CGA-A nrPDB 129 1e-30 5FCR-A nrPDB 129 1e-30 5UGG-A nrPDB 128 2e-30 3TK9-A nrPDB 127 6e-30 1IAU-A nrPDB 126 8e-30 5XRF-A nrPDB 126 9e-30 1EKB-B nrPDB 125 1e-29 5TJX-A nrPDB 125 1e-29 3G01-A nrPDB 125 2e-29 5GVT-A nrPDB 124 4e-29 4DUR-A nrPDB 124 5e-29 2F91-A nrPDB 122 2e-28 3W94-A nrPDB 121 3e-28 1NN6-A nrPDB 121 3e-28 4DGJ-A nrPDB 121 4e-28 3T2N-A nrPDB 120 6e-28 2F83-A nrPDB 120 8e-28 3P8G-A nrPDB 119 9e-28 6I44-A nrPDB 119 1e-27 6AOD-C nrPDB 119 1e-27 1P57-B nrPDB 118 2e-27 1X7A-C nrPDB 118 2e-27 1KYN-A nrPDB 117 7e-27 1AZZ-A nrPDB 116 1e-26 2XXL-A nrPDB 115 2e-26 1BRU-P nrPDB 114 5e-26 4Z6A-H nrPDB 112 2e-25 1A5I-A nrPDB 112 2e-25 2RDL-A nrPDB 112 2e-25 3LC3-A nrPDB 111 4e-25 4Q7Y-A nrPDB 110 4e-25 1BDA-A nrPDB 110 4e-25 2KAI-A nrPDB 110 7e-25 4XDE-A nrPDB 107 7e-24 1FIZ-A nrPDB 106 1e-23 1SC8-U nrPDB 105 2e-23 1FUJ-A nrPDB 104 4e-23 3F6U-H nrPDB 104 5e-23 1YC0-A nrPDB 104 5e-23 2V35-A nrPDB 103 6e-23 4IGD-A nrPDB 103 7e-23 1MKW-K nrPDB 103 7e-23 1ELT-A nrPDB 103 8e-23 3RP2-A nrPDB 102 2e-22 4DJZ-B nrPDB 102 2e-22 4MPW-A nrPDB 102 2e-22 1Q3X-A nrPDB 102 2e-22 2OQ5-A nrPDB 101 3e-22 5XW8-A nrPDB 101 4e-22 2XRC-A nrPDB 101 4e-22 1EQ9-A nrPDB 100 5e-22 2R0L-A nrPDB 100 5e-22 2OCV-B nrPDB 100 6e-22 1ETT-H nrPDB 100 7e-22 3K65-B nrPDB 100 8e-22 3NXP-A nrPDB 100 8e-22 5LHN-A nrPDB 100 9e-22 1LTO-A nrPDB 100 9e-22 4FXG-H nrPDB 100 1e-21 4NZQ-A nrPDB 99 2e-21 1ZJK-A nrPDB 99 2e-21 5O32-I nrPDB 99 2e-21 1FIW-A nrPDB 99 2e-21 1PQ7-A nrPDB 98 3e-21 4H4F-A nrPDB 97 5e-21 1PYT-D nrPDB 97 9e-21 1AE5-A nrPDB 96 2e-20 4KKD-A nrPDB 95 3e-20 4IW4-E nrPDB 94 5e-20 5TO3-B nrPDB 94 5e-20 2ZKS-A nrPDB 94 6e-20 1VR1-H nrPDB 92 2e-19 1SI5-H nrPDB 92 2e-19 1FON-A nrPDB 91 6e-19 5KWM-A nrPDB 88 4e-18 1KIG-H nrPDB 87 5e-18 2ASU-B nrPDB 87 7e-18 2OLG-A nrPDB 87 8e-18 5UBM-A nrPDB 86 1e-17 1C5M-D nrPDB 86 2e-17 1ELV-A nrPDB 86 2e-17 4J1Y-A nrPDB 84 5e-17 1YM0-A nrPDB 84 6e-17 1PPF-E nrPDB 84 6e-17 2B9L-A nrPDB 81 4e-16 1AKS-B nrPDB 80 9e-16 4BXW-A nrPDB 77 6e-15 3H7O-A nrPDB 75 3e-14 2HLC-A nrPDB 74 4e-14 6BQM-A nrPDB 74 8e-14 2JET-B nrPDB 74 9e-14 3H7T-A nrPDB 69 3e-12 3VGC-B nrPDB 68 3e-12 4LK4-A nrPDB 67 6e-12 1BBR-H nrPDB 67 6e-12 1RIW-B nrPDB 66 1e-11 1M9U-A nrPDB 65 4e-11 3RU4-E nrPDB 64 5e-11 3I77-A nrPDB 64 6e-11 2JET-C nrPDB 62 3e-10 4X0L-C nrPDB 60 8e-10 4WJG-C nrPDB 60 1e-09 1MD7-A nrPDB 59 3e-09 2QY0-B nrPDB 58 5e-09 1GPZ-A nrPDB 57 7e-09 2FMJ-A nrPDB 57 7e-09 2I6S-A nrPDB 55 3e-08 1EPT-B nrPDB 53 2e-07 3BEU-A nrPDB 52 2e-07 1DLE-A nrPDB 52 4e-07 2WIN-I nrPDB 51 4e-07 2OK5-A nrPDB 51 5e-07 4F4O-C nrPDB 46 2e-05 1BBR-E nrPDB 45 5e-05 2HNT-F nrPDB 44 8e-05 3F1S-B nrPDB 42 2e-04 3H5C-B nrPDB 42 3e-04 2HNT-C nrPDB 41 6e-04 2HNT-E nrPDB 39 0.003 3RSZ-A nrPDB 31 0.62 4XZY-A nrPDB 28 3.4 1GEG-A nrPDB 28 5.8 >1AO5-A nrPDB Length = 237 Score = 489 bits (1258), Expect = e-139, Method: Compositional matrix adjust. Identities = 235/237 (99%), Positives = 237/237 (100%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 VVGGFNC+KNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFS+DLMLLRLSKPADITDVVKPIALPTK Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 237 >1SGF-G nrPDB Length = 237 Score = 358 bits (920), Expect = e-100, Method: Compositional matrix adjust. Identities = 169/236 (71%), Positives = 194/236 (82%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGGF C+KNSQPW VAVY +++CGGVLLD NWVLTAAHCY D Y+VWLGKN LF++E Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 PSAQHR VSK+ PHPGFNMSL+ D+SNDLMLLRLSKPADITD VKPI LPT+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPK GS CLASGWGSITPT++Q DDL CV + LLPNE+CAK +++KVTD MLCAGEM G Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKDTC+ DSGGPLICDG+LQG TS+G PCG+P +P +YT L KF SWIKDTM KN Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKN 236 >1SGF-A nrPDB Length = 240 Score = 347 bits (889), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 169/244 (69%), Positives = 195/244 (79%), Gaps = 5/244 (2%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLG 76 AAPP+QS+V +C+ NSQPW VAVY ++ CGGVLLDRNWVLTAAHCY D+Y+VWLG Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLG 55 Query: 77 KNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVV 136 KN ++EPS QHRLVSK+ PHP FNMSLL T P D+SNDLMLLRLSKPADITDVV Sbjct: 56 KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVV 115 Query: 137 KPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 KPI LPT+EPK GS CLASGWGS TP +++ PDDLQCV + LLPNE+C K + KVTD M Sbjct: 116 KPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM 175 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 LCAGEM GG TC DSGGPLICDGILQG TS+GP PCG+P P++YT LIKF+SWI++T Sbjct: 176 LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 257 MMKN 260 M N Sbjct: 236 MANN 239 >1TON-A nrPDB Length = 235 Score = 297 bits (760), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 148/236 (62%), Positives = 170/236 (72%), Gaps = 2/236 (0%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+KNSQPWQVAV E++CGGVL+D +WV+TAAHCY + Y+V LG+N LF++E Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 P AQ RLV +SF HP + ++ T P D SNDLMLL LS+PADIT VK I LPTK Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPK GS CLASGWGS P+ DLQCV I LL NE C + Y VTDVMLCAGEM G Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKDTC DSGGPLICDG+LQG TS G PC KP PAIY LIKF SWIK M +N Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKEN 234 >1SPJ-A nrPDB Length = 238 Score = 297 bits (760), Expect = 4e-81, Method: Compositional matrix adjust. Identities = 136/238 (57%), Positives = 178/238 (74%), Gaps = 1/238 (0%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+++SQPWQ A+Y+ CGG+L+ R WVLTAAHC D Y++WLG++ LF +E Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD-ITDVVKPIALPT 143 +AQ VS+SFPHPGFNMSLL T D+S+DLMLLRL++PAD ITD VK + LPT Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 144 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 203 +EP+ GS CLASGWGSI P + PDDLQCV + +LPN+ C K ++QKVTD MLC G + Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GGKDTC DSGGPL+CDG+LQG TS+G VPCG P P++ ++ + WI+DT+ +N+ Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAENS 238 >4NFE-A nrPDB Length = 237 Score = 283 bits (723), Expect = 6e-77, Method: Compositional matrix adjust. Identities = 135/236 (57%), Positives = 169/236 (71%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+K+SQPWQVAVY CGGVL+ WVLTAAHC +VWLG++ LF+ E Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q VS SFPHP +NMSLL Q++ P D S+DLMLLRLS+PA ITDVVK + LPT+ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EP G+ C ASGWGSI P + +P LQCV + LL N+ CA+ Y +KVT+ MLCAG G Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKDTC DSGGPL+C+G+LQG TS+GP PC P PA+YT ++ + WIKDT+ N Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 236 >3QUM-P nrPDB Length = 237 Score = 260 bits (664), Expect = 4e-70, Method: Compositional matrix adjust. Identities = 124/236 (52%), Positives = 166/236 (70%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+K+SQPWQV V + +CGGVL+ WVLTAAHC ++ + LG++ LF E Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q VS SFPHP ++MSLL + + PG D S+DLMLLRLS+PA++TD VK + LPT+ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EP G+ C ASGWGSI P + P LQCV + ++ N+ CA+V+ QKVT MLCAG G Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GK TC DSGGPL+C+G+LQG TS+G PC P P++YT ++ + WIKDT++ N Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 236 >1GVZ-A nrPDB Length = 237 Score = 233 bits (594), Expect = 6e-62, Method: Compositional matrix adjust. Identities = 113/237 (47%), Positives = 154/237 (64%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++GG+ C+K+S+PWQVAVY+Q CGGVL+ WVLTAAHC D Y++WLG++ L ++E Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 +AQ VS SF P F++SLL + + P D S+DLMLLRL++PA ITD VK + LPT+ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPK GS C SGWG I+ + LQCV + L NE CA+ Y +K+T+ +LCA Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 C DSGG LICDG+ QG TS+G C ++T ++ WIK+T+ KN+ Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKNS 237 >5MS3-A nrPDB Length = 228 Score = 202 bits (515), Expect = 9e-53, Method: Compositional matrix adjust. Identities = 102/230 (44%), Positives = 140/230 (60%), Gaps = 9/230 (3%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C+ +SQPWQ A++ ++ +CGGVL+ NWVLTAAHC +Y V LG + L ++ Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q V +S PHP +N S + D ++DLMLL+L A + VKPI+L Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 +PG KC SGWG++T R PD L C + + P + C Y ++TD M+CAG G Sbjct: 113 CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAGSSKG 172 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 DTC+ DSGGPL+CDG LQG TS+G PCG+ P +YTN+ ++ WIK Sbjct: 173 A-DTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIK 221 >1NPM-A nrPDB Length = 225 Score = 201 bits (510), Expect = 4e-52, Method: Compositional matrix adjust. Identities = 100/233 (42%), Positives = 139/233 (59%), Gaps = 9/233 (3%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++ G C +SQPWQ A++ + ICGGVL+ WVLTAAHC +Y V LG + L + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q V++S HP +N S D S+D+ML+RL A++ D VKP+ L Sbjct: 61 QPEQEIQVAQSIQHPCYNNS--------NPEDHSHDIMLIRLQNSANLGDKVKPVQLANL 112 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 PK G KC+ SGWG++T + P+ L C + + C + Y K+T+ M+CAG G Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAGSSNG 172 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 DTC+ DSGGPL+CDG+LQG TS+G PCGKP P +YT + ++ +WIK TM Sbjct: 173 A-DTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >3BSQ-A nrPDB Length = 227 Score = 193 bits (490), Expect = 8e-50, Method: Compositional matrix adjust. Identities = 98/233 (42%), Positives = 135/233 (57%), Gaps = 13/233 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++ G C + S PWQVA+ + CGGVL++ WVLTAAHC +++Y V LG + L Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLGDRR 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 AQ SKSF HPG++ + NDLML++L+ A ++ +VK + LP++ Sbjct: 61 --AQRIKASKSFRHPGYSTQTHV-----------NDLMLVKLNSQARLSSMVKKVRLPSR 107 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 PG+ C SGWG+ T P DL CV + L+ ++C KVY + + MLCAG Sbjct: 108 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 K+ C DSGGPL+C G LQG S+G PCG+P P +YT + KF WI DTM Sbjct: 168 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTM 220 >5ZFH-A nrPDB Length = 224 Score = 191 bits (484), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 95/233 (40%), Positives = 135/233 (57%), Gaps = 13/233 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++ G+ CK+ S PWQVA+ + CGGVL+D+ WVLTAAHC + QY+V LG +K+ + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGDQ- 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 SAQ +KSF HPG++ + ND+ML+RL +P ++ V+ + LP Sbjct: 60 -SAQKIKATKSFRHPGYSTKTHV-----------NDIMLVRLDEPVKMSSKVEAVQLPEH 107 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 PG+ C SGWG+ T P DL C + L+ + C KVY + MLCAG Sbjct: 108 CEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 +TC DSGGPL+C+ LQG S+G PCG+P P +YT + K+ W+ +TM Sbjct: 168 KTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETM 220 >1A0J-A nrPDB Length = 223 Score = 186 bits (472), Expect = 8e-48, Method: Compositional matrix adjust. Identities = 89/236 (37%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+KNS +Q ++ H CGG L+ WV++AAHCY + +V LG++ + E Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q K HP +N + ND+ML++LSKPA + V +ALP+ Sbjct: 60 GTEQFIDSVKVIMHPSYN-----------SRNLDNDIMLIKLSKPASLNSYVSTVALPSS 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 G++CL SGWG+++ + PD L+C+ + +L + +C Y ++T M CAG M G Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKD+C+ DSGGP++C+G LQG S+G C + P +YT + + SWI TM N Sbjct: 169 GKDSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1UTJ-A nrPDB Length = 242 Score = 184 bits (467), Expect = 3e-47, Method: Compositional matrix adjust. Identities = 94/234 (40%), Positives = 137/234 (58%), Gaps = 14/234 (5%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQE 83 ++VGG+ CK SQP QV++ H CGG L++ NWV++AAHCY + EV LG++ + Sbjct: 20 KIVGGYECKPYSQPHQVSLN-SGYHFCGGSLVNENWVVSAAHCYKSRVEVRLGEHNIKVT 78 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 E S Q S+ HP ++ + ND+ML++LSKPA + V+P+ALPT Sbjct: 79 EGSEQFISSSRVIRHPNYS-----------SYNIDNDIMLIKLSKPATLNTYVQPVALPT 127 Query: 144 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 203 G+ C SGWG+ T + + LQC+ I +L +C Y +T+ M CAG + Sbjct: 128 SCAPAGTMCTVSGWGN-TMSSTADSNKLQCLNIPILSYSDCNNSYPGMITNAMFCAGYLE 186 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 GGKD+C+ DSGGP++C+G LQG S+G C +PG P +Y + FN W+ TM Sbjct: 187 GGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVYAKVCIFNDWLTSTM 239 >5FXL-A nrPDB Length = 246 Score = 182 bits (462), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 95/256 (37%), Positives = 144/256 (56%), Gaps = 15/256 (5%) Query: 7 FLALSLGGIDAAPPLQS--RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAA 64 F+ L+L G A P+ ++VGG+ C N+ P+QV++ H CGG L++ WV++AA Sbjct: 4 FIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSL-NSGYHFCGGSLINSQWVVSAA 62 Query: 65 HCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLL 124 HCY +V LG++ + E + Q SKS HP +N + L +ND+ML+ Sbjct: 63 HCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTL-----------NNDIMLI 111 Query: 125 RLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 +L A + V I+LPT G++CL SGWG+ + PD L+C+ +L + +C Sbjct: 112 KLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSC 171 Query: 185 AKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYT 244 Y ++T M CAG + GGKD+C+ DSGGP++C G LQG S+G C + P +YT Sbjct: 172 KSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYT 230 Query: 245 NLIKFNSWIKDTMMKN 260 + + SWIK T+ N Sbjct: 231 KVCNYVSWIKQTIASN 246 >2PSX-A nrPDB Length = 227 Score = 181 bits (460), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 94/239 (39%), Positives = 138/239 (57%), Gaps = 14/239 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHI-CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQE 83 ++ G +C ++QPWQ A+ + + CG VL+ W+LTAAHC + V LG L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 84 EPSAQHRLVS-KSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 S Q KS PHPG++ PG SNDLML++L++ T V+PI + Sbjct: 61 YESGQQMFQGVKSIPHPGYSH---------PG--HSNDLMLIKLNRRIRPTKDVRPINVS 109 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEM 202 + P G+KCL SGWG+ + P LQC+ I++L + C Y +++ D M CAG+ Sbjct: 110 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDK 169 Query: 203 GGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 G +D+C+ DSGGP++C+G LQG S+G PC +P P +YTNL KF WI++T+ N+ Sbjct: 170 AG-RDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 227 >1F7Z-A nrPDB Length = 233 Score = 181 bits (460), Expect = 2e-46, Method: Compositional matrix adjust. Identities = 92/236 (38%), Positives = 139/236 (58%), Gaps = 13/236 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C++NS P+QV++ H CGG L++ WV++AAHCY + +V LG++ + E Sbjct: 11 IVGGYTCQENSVPYQVSLN-SGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLE 69 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q +K HP F+ L +ND+ML++LS P + V +ALP+ Sbjct: 70 GNEQFVNAAKIIKHPNFDRKTL-----------NNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 G++CL SGWG+ + +PD LQC+ LLP +C Y K+TD M+C G + G Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKD+C+ DSGGP++C+G LQG S+G C P P +YT + + WI+DT+ N Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >2BDH-A nrPDB Length = 223 Score = 179 bits (455), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 96/234 (41%), Positives = 137/234 (58%), Gaps = 14/234 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL-FQE 83 ++ G +C +SQPWQ A+ + E C GVL+ WVL+AAHC+ + Y + LG + L + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 EP +Q S S HP +N LL +NDLML++L + +D ++ I++ + Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 109 Query: 144 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 203 + P G+ CL SGWG + R P LQCV ++++ E C+K+Y M CAG Sbjct: 110 QCPTAGNSCLVSGWGLLANGR--MPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQ 167 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 KD+C DSGGPLIC+G LQG S+G PCG+ GVP +YTNL KF WI+ T+ Sbjct: 168 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTV 221 >4WWY-A nrPDB Length = 224 Score = 179 bits (455), Expect = 8e-46, Method: Compositional matrix adjust. Identities = 91/237 (38%), Positives = 137/237 (57%), Gaps = 13/237 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+NC++NS P+QV++ H CGG L++ WV++A HCY + +V LG++ + E Sbjct: 1 IVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q +K HP ++ L +ND+ML++LS A I V I+LPT Sbjct: 60 GNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINAHVSTISLPTA 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P G+KCL SGWG+ + PD+LQC+ +L C Y K+T M C G + G Sbjct: 109 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKD+C+ DSGGP++C+G LQG S+G C + P +YT + + WIK+T+ N+ Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAANS 224 >5C67-A nrPDB Length = 224 Score = 177 bits (449), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 91/237 (38%), Positives = 135/237 (56%), Gaps = 13/237 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C++NS P+QV++ H CGG L+ WV++AAHCY + +V LG++ + E Sbjct: 1 IVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q +K HP +N L ND+ML++LS PA I V I+LPT Sbjct: 60 GNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVINARVSTISLPTA 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P G++CL SGWG+ PD+L+C+ +L C Y K+T+ M C G + G Sbjct: 109 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKD+C+ D+GGP++C+G LQG S+G C P +YT + + WIKDT+ N+ Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAANS 224 >4AN7-A nrPDB Length = 231 Score = 172 bits (435), Expect = 2e-43, Method: Compositional matrix adjust. Identities = 86/237 (36%), Positives = 134/237 (56%), Gaps = 13/237 (5%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQE 83 ++VGG+ C NS P+QV++ H CGG L++ WV++AAHCY + +V LG++ + Sbjct: 8 KIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVL 66 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 E + Q +K HP FN G ND+ML++LS PA + V ++LP Sbjct: 67 EGNEQFINAAKIITHPNFN-----------GNTLDNDIMLIKLSSPATLNSRVATVSLPR 115 Query: 144 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 203 G++CL SGWG+ + P LQC+ +L + +C Y ++T M+C G + Sbjct: 116 SCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLE 175 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GGKD+C+ DSGGP++C+G LQG S+G C + P +YT + + +WI+ T+ N Sbjct: 176 GGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >2EEK-A nrPDB Length = 220 Score = 171 bits (432), Expect = 4e-43, Method: Compositional matrix adjust. Identities = 85/233 (36%), Positives = 134/233 (57%), Gaps = 14/233 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C K+SQ QV++ H CGG L+ ++WV++AAHCY V LG++ + E Sbjct: 1 IVGGYECTKHSQAHQVSLN-SGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q+ S HP ++ + +ND+ML++L+KPA + V +ALPT+ Sbjct: 60 GTEQYISSSSVIRHPNYS-----------SYNINNDIMLIKLTKPATLNQYVHAVALPTE 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 + C SGWG+ T + D LQC+ + +L + +CA Y +T M CAG + G Sbjct: 109 CAADATMCTVSGWGN-TMSSVADGDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEG 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 GKD+C+ DSGGP++C+G+LQG S+G C + P +Y + + W++DTM Sbjct: 168 GKDSCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTM 219 >2PKA-B nrPDB Length = 152 Score = 169 bits (428), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 86/149 (57%), Positives = 106/149 (71%), Gaps = 2/149 (1%) Query: 114 GADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITP--TRWQKPDDL 171 G D+S+DLMLLRL PA ITD VK + LPT+EP+ GS C ASGWGSI P ++ PD++ Sbjct: 3 GKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDEI 62 Query: 172 QCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGP 231 QCV +TLL N CA + KVT+ MLCAG + GGKDTC DSGGPLIC+G+ QG TS+G Sbjct: 63 QCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWGH 122 Query: 232 VPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 PCG P+IYT LI + WI DT+ +N Sbjct: 123 TPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >6QHB-A nrPDB Length = 223 Score = 167 bits (423), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 88/233 (37%), Positives = 133/233 (57%), Gaps = 13/233 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +V G C K S P+Q A+Y +CGGVL+ WVLTAAHC +V+LGK+ L Q+E Sbjct: 1 LVHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 S + V ++ HP ++ A D+MLLRL++PA ++++++P+ L Sbjct: 61 SSQEQSSVVRAVIHPDYD-----------AASHDQDIMLLRLARPAKLSELIQPLPLERD 109 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 + C GWG + PD +QC +I L+ E C Y ++T MLCAG+ Sbjct: 110 CSAQTTSCHILGWGKTADGDF--PDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKY 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 GKD+C+ DSGGPL+C L+G S+G +PCG P +YTN+ ++ +WI+ T+ Sbjct: 168 GKDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTI 220 >2TLD-E nrPDB Length = 220 Score = 167 bits (423), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 89/236 (37%), Positives = 132/236 (55%), Gaps = 16/236 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C N+ P+QV++ H CGG L++ WV++AAHCY +V LG++ + E Sbjct: 1 IVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q SKS HP +N + L +ND+ML++L A + V I+LPT Sbjct: 60 GNEQFISASKSIVHPSYNSNTL-----------NNDIMLIKLKSAASLNSRVASISLPTS 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 G++CL SGWG+ + PD L+C+ +L + +C Y ++T M CAG GG Sbjct: 109 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 D+C+ DSGGP++C G LQG S+G C K P +YT + + SWIK T+ N Sbjct: 169 --DSCQGDSGGPVVCSGKLQGIVSWGS-GCAK-NKPGVYTKVCNYVSWIKQTIASN 220 >1FXY-A nrPDB Length = 228 Score = 160 bits (406), Expect = 4e-40, Method: Compositional matrix adjust. Identities = 88/240 (36%), Positives = 124/240 (51%), Gaps = 15/240 (6%) Query: 25 VVGGFNCKKNSQPWQ-VAVYYQKEHICGGVLLDRNWVLTAAHCY--VDQYEVWLGKNKLF 81 +VGG+NCK PWQ + + + E CGG +L ++LTAAHC +++V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 QEE V H F DF D+ +LRL P V P +L Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETY---------DF--DIAVLRLKTPITFRMNVAPASL 109 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGE 201 PT P G+KCL SGWG+ + PD+LQC+ +L C Y K+T M C G Sbjct: 110 PTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGF 169 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 + GGKD+C+ DSGGP++C+G LQG S+G C + P +YT + + WIK+T+ N+ Sbjct: 170 LEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAANS 228 >5LPF-A nrPDB Length = 234 Score = 160 bits (404), Expect = 7e-40, Method: Compositional matrix adjust. Identities = 88/233 (37%), Positives = 128/233 (54%), Gaps = 5/233 (2%) Query: 28 GFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSA 87 G C + SQPWQV+++ C GVL+D++WVLTAAHC +G + L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GE 65 Query: 88 QHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK 147 Q R ++S HP ++ I P +DLMLL+L++P + V+ + LP + + Sbjct: 66 QLRRTTRSVVHPKYHQGS---GPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 148 PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKD 207 PG +C +GWG+ R + L C IT+L + C Y VT+ M+CAG + G+D Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQD 181 Query: 208 TCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 C+ DSGGPL+CD LQG S+G PCG PA+YT + K+ SWI + N Sbjct: 182 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >4GSO-A nrPDB Length = 232 Score = 154 bits (389), Expect = 4e-38, Method: Compositional matrix adjust. Identities = 88/237 (37%), Positives = 119/237 (50%), Gaps = 11/237 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N P+ +A Y + CG L+++ WV+TAAHC +++ LG + Sbjct: 1 VLGGDECDINEHPF-LAFLYSHGYFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P NMS ++ D+ML++L KP + + P++LP+ Sbjct: 60 EDEQTRNPKEKFICPNKNMSEVL----------DKDIMLIKLDKPISNSKHIAPLSLPSN 109 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P GS C GWGSIT PD C I L+ E C Y LCAG + G Sbjct: 110 PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEG 169 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKDTC DSGGPLIC+G QG SYG CG+ P IYTN+ + WI+ + N Sbjct: 170 GKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGNT 226 >1EUF-A nrPDB Length = 227 Score = 150 bits (379), Expect = 6e-37, Method: Compositional matrix adjust. Identities = 86/240 (35%), Positives = 124/240 (51%), Gaps = 20/240 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG K +S+P+ + ++ K HICGG L+ ++VLTAAHC V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + E + Q V + PHP +N L +ND+MLL+L++ ADITD V PI L Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETL-----------ANDIMLLKLTRKADITDKVSPINL 109 Query: 142 PTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCA 199 P E KPG C +GWG + D LQ V + + E C + + +CA Sbjct: 110 PRSLAEVKPGMMCSVAGWGRLG-VNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICA 168 Query: 200 GEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 G+ K++ DSGGPL+C+G+ QG SYG P +YT + F SWI TM + Sbjct: 169 GDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMRR 225 >2AIQ-A nrPDB Length = 231 Score = 148 bits (374), Expect = 2e-36, Method: Compositional matrix adjust. Identities = 85/237 (35%), Positives = 119/237 (50%), Gaps = 12/237 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N + +A+ Y +CGG L+++ WVLTA HC ++LG + L Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 A R FP + TI + D+ML+RL++P + + P++LP+ Sbjct: 60 KDALRR-----FPKEKYFCLNTRNDTI-----WDKDIMLIRLNRPVRNSAHIAPLSLPSN 109 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P GS C GWG+IT PD C I +L C Y + + LCAG + G Sbjct: 110 PPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAY-KGLAATTLCAGILEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKDTC+ DSGGPLIC+G QG S G PC +P P IYT + + WI+ + N Sbjct: 169 GKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNT 225 >3S9B-A nrPDB Length = 234 Score = 146 bits (369), Expect = 7e-36, Method: Compositional matrix adjust. Identities = 84/239 (35%), Positives = 122/239 (51%), Gaps = 15/239 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHI--CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 VVGG C N P+ VA+Y C G L++R WVLTAAHC + LG + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 Q R+ + + P G D D+ML+RL +P + + P++LP Sbjct: 61 RNEDEQIRVPRGKY--------FCLNTKFPNGLD--KDIMLIRLRRPVTYSTHIAPVSLP 110 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV-MLCAGE 201 ++ GS+C GWG I+ T + PD C I ++ ++ C +Y D LCAG Sbjct: 111 SRSRGVGSRCRIMGWGKISTTTY--PDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGI 168 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 + GG+DTC DSGGPLIC+G + G + G PCG+ PA+YT + +N+WI+ + N Sbjct: 169 LKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >1OP0-A nrPDB Length = 234 Score = 142 bits (359), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 88/238 (36%), Positives = 122/238 (51%), Gaps = 11/238 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N + VA + CGG L++ WV+TAAHC +++ LG + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P N + ++ D+ML++L KP + + P++LP+ Sbjct: 61 EDEQTRNPKEKFICPNKNNNEVL----------DKDIMLIKLDKPISNSKHIAPLSLPSS 110 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV-MLCAGEMG 203 P GS C GWGSITP + PD C I LL + C Y + + + LCAG + Sbjct: 111 PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GGKDTC DSGGPLIC+G QG SYG PCG+ P IYTN+ + WI+ + N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGNT 228 >1FDP-A nrPDB Length = 235 Score = 142 bits (358), Expect = 1e-34, Method: Compositional matrix adjust. Identities = 82/249 (32%), Positives = 132/249 (53%), Gaps = 23/249 (9%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD----QYE 72 AAPP + R++GG + +++P+ +V H+CGGVL+ WVL+AAHC D + + Sbjct: 1 AAPP-RGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQ 59 Query: 73 VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADI 132 V LG + L Q EPS + V ++ PHP + +DL+LL+LS+ A + Sbjct: 60 VLLGAHSLSQPEPSKRLYDVLRAVPHPDSQPDTI-----------DHDLLLLQLSEKATL 108 Query: 133 TDVVKPI--ALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ 190 V+P+ ++ PG+ C +GWG I ++PD LQ V + +L C + Sbjct: 109 GPAVRPLPWQRVDRDVAPGTLCDVAGWG-IVNHAGRRPDSLQHVLLPVLDRATCNRRTHH 167 Query: 191 K--VTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIK 248 +T+ ++CA +D+C+ DSGGPL+C G+L+G + G CG P IYT + Sbjct: 168 DGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVAS 225 Query: 249 FNSWIKDTM 257 + +WI + Sbjct: 226 YAAWIDSVL 234 >4E7N-A nrPDB Length = 238 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 89/242 (36%), Positives = 121/242 (50%), Gaps = 15/242 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEH--ICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 ++GG C N + VA+Y + CGG L+++ WVLTAAHC + + LG + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 Q R+ + F F +S + D+ML+RL P + + P +LP Sbjct: 61 PNEDEQTRVPKEKF----FCLSSKNYTL------WDKDIMLIRLDSPVKNSKHIAPFSLP 110 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ---KVTDVMLCA 199 + P GS C GWG I+PT PD CV I LL E C Y + T LCA Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 200 GEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 G + GGKDTC+ DSGGPLIC+G QG S+G PC +P PA YT + WI++ + Sbjct: 171 GILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAG 230 Query: 260 NA 261 N Sbjct: 231 NT 232 >1BQY-A nrPDB Length = 234 Score = 139 bits (350), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 83/239 (34%), Positives = 123/239 (51%), Gaps = 15/239 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLG--KNKLFQ 82 V GG C N V ++ +CGG L++++WV+TAAHC + +++ G K+ Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 E+ Q R + F P + D+ML++L ++ + P++LP Sbjct: 61 ED--EQTRDPKEKFFCPNRKKD----------DEVDKDIMLIKLDSSVSNSEHIAPLSLP 108 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-QKVTDVMLCAGE 201 + P GS C GWG PT+ PD C I +L + C Y ++V + LCAG Sbjct: 109 SSPPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGI 168 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 + GG+DTC DSGGPLIC+GI QG S+G PCG+PG P +YT + + WIK + N Sbjct: 169 LQGGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >1ORF-A nrPDB Length = 234 Score = 137 bits (346), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 86/242 (35%), Positives = 132/242 (54%), Gaps = 21/242 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQY-EVWLGKNKLFQE 83 ++GG +S+P+ V + ++ IC G L+ ++WVLTAAHC +++ +V LG + + +E Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 EP+ Q LV K FP+P ++ A DL LL+L++ A I V + LP Sbjct: 61 EPTKQIMLVKKEFPYPCYD-----------PATREGDLKLLQLTEKAKINKYVTILHLPK 109 Query: 144 K--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV----ML 197 K + KPG+ C +GWG T D L+ V IT++ + C V M+ Sbjct: 110 KGDDVKPGTMCQVAGWGR-THNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMV 168 Query: 198 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYG-PVPCGKPGVPAIYTNLIKFN-SWIKD 255 CAG + GG+D+C DSG PL+C+G+ +G TS+G CG P P +Y L K + +WI Sbjct: 169 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 228 Query: 256 TM 257 T+ Sbjct: 229 TI 230 >3S69-A nrPDB Length = 234 Score = 136 bits (343), Expect = 7e-33, Method: Compositional matrix adjust. Identities = 84/238 (35%), Positives = 119/238 (50%), Gaps = 11/238 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N VA + C G L++ WVLTAAHC +++ LG + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P ++ D+ML++L ++ + P++LP+ Sbjct: 61 EDEQTRNPKEKFICPNKKNDEVL----------DKDIMLIKLDSRVSNSEHIVPLSLPSS 110 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV-MLCAGEMG 203 P GS C GWGSITP + PD C +I LL + C Y + +T+ LCAG + Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GGKDTC DSGGPLIC+G QG S+G PCG+ P +YT + +N WI+ + N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGNT 228 >1MZD-A nrPDB Length = 240 Score = 135 bits (340), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 86/249 (34%), Positives = 129/249 (51%), Gaps = 29/249 (11%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--------VWL 75 ++GG +S+P+ ++ Y H+CGGVL+D WVLTAAHC QY V L Sbjct: 2 EIIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHC---QYRFTKGQSPTVVL 58 Query: 76 GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV 135 G + L + E S Q + K P + + P SND+ML++L A + Sbjct: 59 GAHSLSKNEASKQTLEIKKFIP-------FSRVTSDPQ----SNDIMLVKLQTAAKLNKH 107 Query: 136 VKPIALPTKEP-KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC-AKVYLQK-- 191 VK + + +K + G+KC +GWG+ P + D L+ V +T+L + C ++ Y Sbjct: 108 VKMLHIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDP 167 Query: 192 -VTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLI-KF 249 +T M+CAG+ G KD+C+ D+GGPLIC G+ S G CG P IYT L K+ Sbjct: 168 FITKDMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGH-ECGVATKPGIYTLLTKKY 226 Query: 250 NSWIKDTMM 258 +WIK ++ Sbjct: 227 QTWIKSNLV 235 >3E0N-B nrPDB Length = 271 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 85/255 (33%), Positives = 127/255 (49%), Gaps = 32/255 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ-----YEVWLGKNK 79 + GG + PWQV++ Y+ H+CGG L+ WVL+AAHC+ + YEV LG ++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L A+ + PHP + LQ G D+ LL+LS+P + ++PI Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY------LQEGSQG-----DIALLQLSRPITFSRYIRPI 109 Query: 140 ALPTKEPK--PGSKCLASGWGSITPT-RWQKPDDLQCVFITLLPNENCAKVYL------- 189 +LP + G C +GWG + P+ P LQ + + L+ E C +Y Sbjct: 110 SLPAAQASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEE 169 Query: 190 -QKVTDVMLCAGEMGGGKDTCRDDSGGPLIC--DGI--LQGTTSYGPVPCGKPGVPAIYT 244 V + M+CAG + GGKD C+ DSGGPL C +G+ L G S+G CG P +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYT 228 Query: 245 NLIKFNSWIKDTMMK 259 + SWI+ + + Sbjct: 229 LASSYASWIQSKVTE 243 >3DFJ-A nrPDB Length = 263 Score = 133 bits (335), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 85/255 (33%), Positives = 126/255 (49%), Gaps = 32/255 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ-----YEVWLGKNK 79 + GG + PWQV++ Y+ H+CGG L+ WVL+AAHC+ + YEV LG ++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L A+ + PHP + LQ G D+ LL+LS+P + ++PI Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY------LQEGSQG-----DIALLQLSRPITFSRYIRPI 109 Query: 140 ALPTKEPK--PGSKCLASGWGSITPT-RWQKPDDLQCVFITLLPNENCAKVYL------- 189 +LP G C +GWG + P+ P LQ + + L+ E C +Y Sbjct: 110 SLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEE 169 Query: 190 -QKVTDVMLCAGEMGGGKDTCRDDSGGPLIC--DGI--LQGTTSYGPVPCGKPGVPAIYT 244 V + M+CAG + GGKD C+ DSGGPL C +G+ L G S+G CG P +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYT 228 Query: 245 NLIKFNSWIKDTMMK 259 + SWI+ + + Sbjct: 229 LASSYASWIQSKVTE 243 >1FI8-A nrPDB Length = 228 Score = 133 bits (334), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 84/245 (34%), Positives = 124/245 (50%), Gaps = 26/245 (10%) Query: 25 VVGGFNCKKNSQPW----QVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG K +S+P+ Q+ Y CGG L+ ++VLTAAHC + +V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 ++E Q V K PHP +N + SND+MLL+L A + VKP+ Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 109 Query: 141 LPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA---KVYLQKVTDV 195 LP + + KPG C +GWG + P + D LQ V +T+ ++ C K Y K ++ Sbjct: 110 LPRRNVKVKPGDVCYVAGWGKLGPM-GKYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 168 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 CAG+ + + R DSGGPL+C + G SYG P +T + F SWIK Sbjct: 169 --CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKK 223 Query: 256 TMMKN 260 TM K+ Sbjct: 224 TMKKS 228 >2CGA-A nrPDB Length = 245 Score = 129 bits (325), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 82/246 (33%), Positives = 119/246 (48%), Gaps = 22/246 (8%) Query: 23 SRVVGGFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWL-GKNKL 80 SR+V G S PWQV++ + H CGG L++ NWV+TAAHC V +V + G+ Sbjct: 14 SRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQ 73 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 Q ++K F + +N SL + +ND+ LL+LS A + V + Sbjct: 74 GSSSEKIQKLKIAKVFKNSKYN-SLTI----------NNDITLLKLSTAASFSQTVSAVC 122 Query: 141 LPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 LP+ G+ C+ +GWG T PD LQ + LL N NC K + K+ D M+C Sbjct: 123 LPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCKKYWGTKIKDAMIC 182 Query: 199 AGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 AG G +C DSGGPL+C L G S+G C P +Y + +W++ Sbjct: 183 AG--ASGVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTC-STSTPGVYARVTALVNWVQ 239 Query: 255 DTMMKN 260 T+ N Sbjct: 240 QTLAAN 245 >5FCR-A nrPDB Length = 234 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 78/245 (31%), Positives = 122/245 (49%), Gaps = 23/245 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGKNK 79 ++GG +++P+ +V H+CGG LLD WVL+AAHC D +V LG + Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L EP + V PHPG L +DL+L +LS+ A + V+P+ Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSL-----------EDDLILFKLSQNASLGPHVRPL 109 Query: 140 AL--PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA-KVYLQKVTDV- 195 L KE +PG+ C +GWG +T ++PD L + ++++ C + Y V + Sbjct: 110 PLQYEDKEVEPGTLCDVAGWGVVTHA-GRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTIN 168 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 M+CA +DTCR DSG PL+C ++G ++G CG P +YT + + WI++ Sbjct: 169 MMCA--ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 Query: 256 TMMKN 260 N Sbjct: 227 ITNGN 231 >5UGG-A nrPDB Length = 251 Score = 128 bits (322), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 88/251 (35%), Positives = 122/251 (48%), Gaps = 34/251 (13%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQ-KEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGK 77 RVVGG +S PWQV++ + H CGG L+ WVLTAAHC Y+V LG Sbjct: 21 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 80 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 ++ EP Q VS+ F P D+ LL+LS PA ITD V Sbjct: 81 HQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKVI 123 Query: 138 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL--QKVT 193 P LP+ ++C +GWG T L+ + ++ N+ C + +V Sbjct: 124 PACLPSPNYVVADRTECFITGWGETQGTF--GAGLLKEAQLPVIENKVCNRYEFLNGRVQ 181 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 LCAG + GG D+C+ DSGGPL+C ILQG TS+G + C +P P +Y + +F Sbjct: 182 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRF 240 Query: 250 NSWIKDTMMKN 260 +WI+ M N Sbjct: 241 VTWIEGVMRNN 251 >3TK9-A nrPDB Length = 226 Score = 127 bits (318), Expect = 6e-30, Method: Compositional matrix adjust. Identities = 77/242 (31%), Positives = 125/242 (51%), Gaps = 24/242 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHI---CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG K +S+P+ V + +E CGG+L+ +++VLTAAHC V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 ++E + Q V + PHP +N +FSN++MLL+L + A T V+P+ L Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPK-----------NFSNNIMLLQLERKAKWTTAVRPLRL 109 Query: 142 PTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM-LC 198 P+ + KPG C +GWG ++ + LQ V +T+ + C +++ + +C Sbjct: 110 PSSKAQVKPGQLCSVAGWGYVSMSTL--ATTLQEVLLTVQKDCQCERLFHGNYSRATEIC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGV-PAIYTNLIKFNSWIKDTM 257 G+ + + DSGGPL+C + QG SYG K G P +Y + F WIK TM Sbjct: 168 VGDPKKTQTGFKGDSGGPLVCKDVAQGILSYG----NKKGTPPGVYIKVSHFLPWIKRTM 223 Query: 258 MK 259 + Sbjct: 224 KR 225 >1IAU-A nrPDB Length = 227 Score = 126 bits (317), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 82/241 (34%), Positives = 124/241 (51%), Gaps = 21/241 (8%) Query: 25 VVGGFNCKKNSQPWQ--VAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG K +S+P+ + ++ QK CGG L+ ++VLTAAHC+ V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 ++EP+ Q V + PHP +N +FSND+MLL+L + A T V+P+ L Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKRTRAVQPLRL 109 Query: 142 PTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV-TDVMLC 198 P+ + KPG C +GWG P + LQ V +T+ + C + + LC Sbjct: 110 PSNKAQVKPGQTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 168 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G+ K + + DSGGPL+C+ + QG SYG G P P T + F WIK TM Sbjct: 169 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYG-RNNGMP--PRACTKVSSFVHWIKKTMK 225 Query: 259 K 259 + Sbjct: 226 R 226 >5XRF-A nrPDB Length = 242 Score = 126 bits (317), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 78/237 (32%), Positives = 116/237 (48%), Gaps = 15/237 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK--EHICGGVLLDRNWVLTAAHCYVDQYEVWLG-KNKLF 81 V+GG C N + A + + C G L+ WVL AAHCY ++LG N+ Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 Q + + + + + ++ + D++LL+L+KP + + P++L Sbjct: 67 QFDDEQRRYAIEEHYYRCDEKLT-----------KWEKDVVLLKLNKPVSNSTHIAPLSL 115 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVTDVMLCAG 200 P+ P GS C GWG ++ T+ PD C I LL C Y T +LCAG Sbjct: 116 PSSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAG 175 Query: 201 EMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 + GG DTC DSGGPLICDG QG +G PC +P P +YT + +N WI++ + Sbjct: 176 VLEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNII 232 >1EKB-B nrPDB Length = 235 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 75/247 (30%), Positives = 126/247 (51%), Gaps = 27/247 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV------DQYEVWLGKN 78 +VGG + ++ + PW VA+Y+ + +CG L+ R+W+++AAHC +++ LG + Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 79 KLFQ-EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 P + RL+ + +P +N +ND+ ++ L + TD ++ Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRK-----------NNDIAMMHLEMKVNYTDYIQ 109 Query: 138 PIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVTD 194 PI LP + PG C +GWG++ + D LQ + LL NE C + + +T+ Sbjct: 110 PICLPEENQVFPPGRICSIAGWGALI-YQGSTADVLQEADVPLLSNEKCQQQMPEYNITE 168 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKFN 250 M+CAG GG D+C+ DSGGPL+C +L G TS+G C P P +Y + +F Sbjct: 169 NMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFG-YQCALPNRPGVYARVPRFT 227 Query: 251 SWIKDTM 257 WI+ + Sbjct: 228 EWIQSFL 234 >5TJX-A nrPDB Length = 263 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 81/246 (32%), Positives = 127/246 (51%), Gaps = 28/246 (11%) Query: 23 SRVVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----VDQYEVW 74 +R+VGG PWQV++ + + H+CGG L+ WVLTAAHC+ D + ++ Sbjct: 14 TRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 73 Query: 75 LGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITD 134 G +L + + H + +S + ++D+ L++L P + T+ Sbjct: 74 SGILELSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLEYTE 122 Query: 135 VVKPIALPTKEPKPG--SKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-K 191 KPI+LP+K + C +GWG + + + + LQ V I L+ NE C K Y K Sbjct: 123 FQKPISLPSKGDTSTIYTNCWVTGWG-FSKEKGEIQNILQKVNIPLVTNEECQKRYQDYK 181 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLIC--DGI--LQGTTSYGPVPCGKPGVPAIYTNLI 247 +T M+CAG GGKD C+ DSGGPL+C +G+ L G TS+G C + P +YT + Sbjct: 182 ITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVA 240 Query: 248 KFNSWI 253 ++ WI Sbjct: 241 EYMDWI 246 >3G01-A nrPDB Length = 227 Score = 125 bits (314), Expect = 2e-29, Method: Compositional matrix adjust. Identities = 80/242 (33%), Positives = 119/242 (49%), Gaps = 26/242 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ------KEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKN 78 ++GG +S+P+ YY+ K+ CGG L+ +VLTAAHC V LG + Sbjct: 1 IIGGNEISPHSRPYMA--YYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAH 58 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 + +E + Q V+K+ PHP +N D SND+MLL+L + A T V+P Sbjct: 59 NIKAKEETQQIIPVAKAIPHPDYNPD-----------DRSNDIMLLKLVRNAKRTRAVRP 107 Query: 139 IALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV- 195 + LP + KPG +C +GWG +TP + P L V +T+ ++ C + Sbjct: 108 LNLPRRNAHVKPGDECYVAGWGKVTPD-GEFPKTLHEVKLTVQKDQVCESQFQSSYNRAN 166 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 +C G+ + R DSGGPL+C G SYG P ++T ++ F SWIK Sbjct: 167 EICVGDSKIKGASFRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKK 223 Query: 256 TM 257 TM Sbjct: 224 TM 225 >5GVT-A nrPDB Length = 250 Score = 124 bits (311), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 82/247 (33%), Positives = 128/247 (51%), Gaps = 34/247 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHC-----YVDQYEVW-- 74 +VGG N PWQV++ + + H+CGG ++ R WVLTAAHC Y D + ++ Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 75 -LGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADIT 133 L +++ +E PS++ + + H + +S + + D+ L++L P + T Sbjct: 61 ILSLSEITKETPSSR---IKELIIHQEYKVS-----------EGNYDIALIKLQTPLNYT 106 Query: 134 DVVKPIALPTKEPKPG--SKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK 191 + KPI+LP+K + C +GWG T + + + LQ I L+PNE C K Y Sbjct: 107 EFQKPISLPSKADTNTIYTNCWVTGWG-YTKEQGETQNILQKATIPLVPNEECQKKYRDY 165 Query: 192 VTD-VMLCAGEMGGGKDTCRDDSGGPLICDGI----LQGTTSYGPVPCGKPGVPAIYTNL 246 V + M+CAG GG D C+ DSGGPL+C L G TS+G C + P +YT + Sbjct: 166 VINKQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKV 224 Query: 247 IKFNSWI 253 ++ WI Sbjct: 225 SEYMDWI 231 >4DUR-A nrPDB Length = 791 Score = 124 bits (310), Expect = 5e-29, Method: Compositional matrix adjust. Identities = 88/251 (35%), Positives = 122/251 (48%), Gaps = 34/251 (13%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQ-KEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGK 77 RVVGG +S PWQV++ + H CGG L+ WVLTAAHC Y+V LG Sbjct: 561 RVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAHCLEKSPRPSSYKVILGA 620 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 ++ EP Q VS+ F P D+ LL+LS PA ITD V Sbjct: 621 HQEVNLEPHVQEIEVSRLFLEP-----------------TRKDIALLKLSSPAVITDKVI 663 Query: 138 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL--QKVT 193 P LP+ ++C +GWG T L+ + ++ N+ C + +V Sbjct: 664 PACLPSPNYVVADRTECFITGWGETQGTF--GAGLLKEAQLPVIENKVCNRYEFLNGRVQ 721 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 LCAG + GG D+C+ DSGGPL+C ILQG TS+G + C +P P +Y + +F Sbjct: 722 STELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-LGCARPNKPGVYVRVSRF 780 Query: 250 NSWIKDTMMKN 260 +WI+ M N Sbjct: 781 VTWIEGVMRNN 791 >2F91-A nrPDB Length = 237 Score = 122 bits (305), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 84/248 (33%), Positives = 119/248 (47%), Gaps = 33/248 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE------HICGGVLLDRNWVLTAAHC-YVDQYE----- 72 +VGG + P+Q++ +Q+ H CG + + N+ +TA HC Y D YE Sbjct: 1 IVGGTDATLGEFPYQLS--FQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGL 58 Query: 73 -VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 + G+ + E S Q VSK H F+ +LL ND+ LL+LS Sbjct: 59 QIVAGELDMSVNEGSEQIITVSKIILHENFDYNLL-----------DNDISLLKLSGSLT 107 Query: 132 ITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY-LQ 190 D V PIALP + + +GWG+ T PD LQ V + L+ +E+C Y Sbjct: 108 FNDNVAPIALPEQGHTATGDVIVTGWGT-TSEGGNTPDVLQKVTVPLVSDEDCRADYGAD 166 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLICDGI----LQGTTSYGPVPCGKPGVPAIYTNL 246 ++ D M+CAG GGKD+C+ DSGGPL L G S+G C +PG P +YT + Sbjct: 167 EILDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEV 225 Query: 247 IKFNSWIK 254 WIK Sbjct: 226 SYHVDWIK 233 >3W94-A nrPDB Length = 235 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 78/244 (31%), Positives = 120/244 (49%), Gaps = 23/244 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 VVGG N +K + PW V+++++ H CG L+ R+W+LTAAHC GKN Q Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCV-------YGKNTHLQYW 53 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSN-----DLMLLRLSKPADITDVVKPI 139 + S + + + I +++ D+ ++ L +P + T+ V P+ Sbjct: 54 SAVLGLHAQSSMNSQ--EVQIRQVDRIIINKNYNRRTKEADIAMMHLQQPVNFTEWVLPV 111 Query: 140 ALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVTDVM 196 L +++ G +C +GWG PD LQ + L+ + C ++ + T M Sbjct: 112 CLASEDQHFPAGRRCFIAGWGRDAEGG-SLPDILQEAEVPLVDQDECQRLLPEYTFTSSM 170 Query: 197 LCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSW 252 LCAG GG D+C+ DSGGPL+C L G TS+G V CG+P P Y + F SW Sbjct: 171 LCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFG-VGCGRPERPGAYARVSAFTSW 229 Query: 253 IKDT 256 I +T Sbjct: 230 IAET 233 >1NN6-A nrPDB Length = 228 Score = 121 bits (304), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 82/244 (33%), Positives = 120/244 (49%), Gaps = 26/244 (10%) Query: 25 VVGGFNCKKNSQPW----QVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG CK +S+P+ ++ CGG L+ RN+VLTAAHC V LG + + Sbjct: 3 IIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAHNI 62 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 +EE + Q V K F HP +N S L +D+MLL+L + A +T V + Sbjct: 63 TEEEDTWQKLEVIKQFRHPKYNTSTL-----------HHDIMLLKLKEKASLTLAVGTLP 111 Query: 141 LPTKEP--KPGSKCLASGWGSITPTRWQKP--DDLQCVFITLLPNENCAKVYLQKVTDVM 196 P++ PG C +GWG T KP D LQ V + L+ + C+ + ++ Sbjct: 112 FPSQFNFVPPGRMCRVAGWGR---TGVLKPGSDTLQEVKLRLMDPQACSH-FRDFDHNLQ 167 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 LC G K + DSGGPL+C G+ QG SYG KP PA++T + + WI Sbjct: 168 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQI 224 Query: 257 MMKN 260 + N Sbjct: 225 LQAN 228 >4DGJ-A nrPDB Length = 235 Score = 121 bits (303), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 76/247 (30%), Positives = 121/247 (48%), Gaps = 27/247 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV------DQYEVWLGKN 78 +VGG + K+ + PW V +YY +CG L+ +W+++AAHC ++ LG + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 79 -KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 K P RL+ + +P +N ND+ ++ L + TD ++ Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRK-----------DNDIAMMHLEFKVNYTDYIQ 109 Query: 138 PIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVTD 194 PI+LP + PG C +GWG++ + D LQ + LL NE C + + +T+ Sbjct: 110 PISLPEENQVFPPGRNCSIAGWGTVV-YQGTTADILQEADVPLLSNERCQQQMPEYNITE 168 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKFN 250 M+CAG GG D+C+ DSGGPL+C L G TS+G C P P +Y + +F Sbjct: 169 NMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFG-YECALPNRPGVYARVSRFT 227 Query: 251 SWIKDTM 257 WI+ + Sbjct: 228 EWIQSFL 234 >3T2N-A nrPDB Length = 372 Score = 120 bits (301), Expect = 6e-28, Method: Compositional matrix adjust. Identities = 80/247 (32%), Positives = 118/247 (47%), Gaps = 25/247 (10%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF-- 81 R+VGG + PWQV++ Y H+CGG LL +WVLTAAHC+ ++ V L + ++F Sbjct: 117 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV-LSRWRVFAG 175 Query: 82 ---QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 Q P V H G+ + P + SND+ L+ LS P +T+ ++P Sbjct: 176 AVAQASPHGLQLGVQAVVYHGGY-----LPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 230 Query: 139 IALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKVYLQKVTD 194 + LP G C +GWG+ T Q+ LQ + ++ N+ C A Y ++ Sbjct: 231 VCLPAAGQALVDGKICTVTGWGN-TQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKP 289 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDGILQ--------GTTSYGPVPCGKPGVPAIYTNL 246 M CAG GG D C+ DSGGP +C+ + G S+G C P +YT + Sbjct: 290 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYTKV 348 Query: 247 IKFNSWI 253 F WI Sbjct: 349 SDFREWI 355 >2F83-A nrPDB Length = 625 Score = 120 bits (300), Expect = 8e-28, Method: Compositional matrix adjust. Identities = 79/250 (31%), Positives = 125/250 (50%), Gaps = 22/250 (8%) Query: 16 DAAPPLQSRVVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY--VDQ 70 + ++ R+VGG + PWQV ++ + H+CGG ++ W+LTAAHC+ V+ Sbjct: 379 ECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVES 438 Query: 71 YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 ++ + + + + SF F + +++ A+ D+ LL+L Sbjct: 439 PKILRVYSGILNQSEIKE----DTSF----FGVQEIIIHDQYKMAESGYDIALLKLETTV 490 Query: 131 DITDVVKPIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY 188 + TD +PI LP+K + + C +GWG R + + LQ I L+ NE C K Y Sbjct: 491 NYTDSQRPICLPSKGDRNVIYTDCWVTGWG-YRKLRDKIQNTLQKAKIPLVTNEECQKRY 549 Query: 189 L-QKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIY 243 K+T M+CAG GGKD C+ DSGGPL C L G TS+G C + P +Y Sbjct: 550 RGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVY 608 Query: 244 TNLIKFNSWI 253 TN++++ WI Sbjct: 609 TNVVEYVDWI 618 >3P8G-A nrPDB Length = 241 Score = 119 bits (299), Expect = 9e-28, Method: Compositional matrix adjust. Identities = 86/251 (34%), Positives = 122/251 (48%), Gaps = 32/251 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVD----------QYEV 73 VVGG + + PWQV+++ + HICG L+ NW+++AAHCY+D Q+ Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 74 WLGKNKLFQEE-PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADI 132 +LG + Q P Q R + + HP FN F D+ LL L KPA+ Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFN-----------DFTFDYDIALLELEKPAEY 109 Query: 133 TDVVKPIALP-TKEPKPGSKCL-ASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ 190 + +V+PI LP P K + +GWG T LQ I ++ C + Q Sbjct: 110 SSMVRPICLPDASHVFPAGKAIWVTGWGH-TQYGGTGALILQKGEIRVIQQTTCENLLPQ 168 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLI---CDG-ILQ-GTTSYGPVPCGKPGVPAIYTN 245 ++T M+C G + GG D+C+ DSGGPL DG I Q G S+G C + P +YT Sbjct: 169 QITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD-GCAQRNKPGVYTR 227 Query: 246 LIKFNSWIKDT 256 L F WIK+ Sbjct: 228 LPLFRDWIKEN 238 >6I44-A nrPDB Length = 627 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 80/246 (32%), Positives = 124/246 (50%), Gaps = 28/246 (11%) Query: 23 SRVVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----VDQYEVW 74 +R+VGG PWQV++ + + H+CGG L+ WVLTAAHC+ D + ++ Sbjct: 378 TRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRIY 437 Query: 75 LGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITD 134 G +L + + H + +S + ++D+ L++L P T+ Sbjct: 438 SGILQLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQAPLQYTE 486 Query: 135 VVKPIALPTKEPKPG--SKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-K 191 KPI LP+K + C +GWG + + + LQ V I L+ NE C K Y K Sbjct: 487 FQKPICLPSKGDTSTIYTNCWVTGWG-FSAEAGEIQNILQKVNIPLVTNEECQKRYQDYK 545 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLIC--DGI--LQGTTSYGPVPCGKPGVPAIYTNLI 247 +T M+CAG GGKD C+ D+GGPL+C +G+ L G TS+G C + P +YT + Sbjct: 546 ITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPGVYTKVA 604 Query: 248 KFNSWI 253 ++ WI Sbjct: 605 EYMDWI 610 >6AOD-C nrPDB Length = 245 Score = 119 bits (298), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 78/241 (32%), Positives = 122/241 (50%), Gaps = 22/241 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY--VDQYEVWLGKNK 79 +VGG + PWQV ++ + H+CGG ++ W+LTAAHC+ V+ ++ + Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 + Q+ + SF F + +++ A+ D+ LL+L TD +PI Sbjct: 61 ILQQSEIKE----DTSF----FGVQEIIIHDQYKMAESGYDIALLKLETTVQYTDSQRPI 112 Query: 140 ALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-QKVTDVM 196 +LP+K + + C +GWG R + + LQ I L+ NE C K Y K+T M Sbjct: 113 SLPSKGDRNVIYTDCWVTGWG-YRKLRDKIQNTLQKAKIPLVTNEECQKRYRGHKITHKM 171 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSW 252 +CAG GGKD C+ D+GGPL C L G TS+G C + P +YTN++++ W Sbjct: 172 ICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEYVDW 230 Query: 253 I 253 I Sbjct: 231 I 231 >1P57-B nrPDB Length = 255 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 79/254 (31%), Positives = 120/254 (47%), Gaps = 25/254 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF--- 81 +VGG + PWQV++ Y H+CGG LL +WVLTAAHC+ ++ V L + ++F Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRV-LSRWRVFAGA 59 Query: 82 --QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 Q P V H G+ + P + SND+ L+ LS P +T+ ++P+ Sbjct: 60 VAQASPHGLQLGVQAVVYHGGY-----LPFRDPNSEENSNDIALVHLSSPLPLTEYIQPV 114 Query: 140 ALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKVYLQKVTDV 195 LP G C +GWG+ T Q+ LQ + ++ N+ C A Y ++ Sbjct: 115 CLPAAGQALVDGKICTVTGWGN-TQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKPK 173 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDGILQ--------GTTSYGPVPCGKPGVPAIYTNLI 247 M CAG GG D C+ DSGGP +C+ + G S+G C P +YT + Sbjct: 174 MFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWG-TGCALAQKPGVYTKVS 232 Query: 248 KFNSWIKDTMMKNA 261 F WI + ++ Sbjct: 233 DFREWIFQAIKTHS 246 >1X7A-C nrPDB Length = 235 Score = 118 bits (296), Expect = 2e-27, Method: Compositional matrix adjust. Identities = 77/242 (31%), Positives = 119/242 (49%), Gaps = 23/242 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWL--GKNKLFQ 82 +VGG N K PWQV + + + CGG +++ WV+TAAHC ++ + G+ + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 EP+ Q R V ++ PH +N ++ +S+D+ LL L +P + V PI + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATV---------NKYSHDIALLELDEPLTLNSYVTPICIA 111 Query: 143 TKEP-----KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 197 KE K GS SGWG + R + LQ + + L+ C + + M Sbjct: 112 DKEYTNIFLKFGSG-YVSGWGRVF-NRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMF 169 Query: 198 CAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 CAG GGKD+C+ DSGGP + + L G S+G C G IYT + ++ +WI Sbjct: 170 CAGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAVKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >1KYN-A nrPDB Length = 235 Score = 117 bits (292), Expect = 7e-27, Method: Compositional matrix adjust. Identities = 71/238 (29%), Positives = 118/238 (49%), Gaps = 21/238 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG + +S+P+ + Q + CGG L+ ++VLTAAHC+ V LG + + Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + E + QH ++ HP +N + ND+MLL+LS+ V P+AL Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTI-----------QNDIMLLQLSRRVRRNRNVNPVAL 109 Query: 142 PTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCA 199 P + +PG+ C +GWG ++ R D L+ V + + + C +++ +C Sbjct: 110 PRAQEGLRPGTLCTVAGWGRVSMRR--GTDTLREVQLRVQRDRQCLRIFGSYDPRRQICV 167 Query: 200 GEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G+ K + DSGGPL+C+ + G SYG G P P ++T + F WI+ TM Sbjct: 168 GDRRERKAAFKGDSGGPLLCNNVAHGIVSYGK-SSGVP--PEVFTRVSSFLPWIRTTM 222 >1AZZ-A nrPDB Length = 226 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 76/236 (32%), Positives = 118/236 (50%), Gaps = 23/236 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC-----YVDQYEVWLGKNK 79 +VGG NS P Q A++ + CGG L+ W+LTAAHC +VD V LG + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVD---VVLGAHN 57 Query: 80 LFQEEPSAQHRLVSKSFP-HPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 + +E+ + Q + S F H +N ++ SND+ ++RL P +T + Sbjct: 58 I-REDEATQVTIQSTDFTVHENYNSFVI-----------SNDIAVIRLPVPVTLTAAIAT 105 Query: 139 IALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 + LP+ + G+ +GWG + + D L+ V + ++ N +C VY VTD +C Sbjct: 106 VGLPSTDVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNIC 164 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 + GGK TC DSGGPL +G+ G TS+G + G P +T + F WI+ Sbjct: 165 I-DSTGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >2XXL-A nrPDB Length = 408 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 83/272 (30%), Positives = 127/272 (46%), Gaps = 29/272 (10%) Query: 15 IDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYV-- 68 D L RV G+ K +S+PW + YQ+ +CGG ++ ++LTAAHC Sbjct: 109 FDCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGL 168 Query: 69 --DQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSL--LMLQTIPPGADFSNDLMLL 124 D YE+ LG++++ EE Q K P P N+ + ++ +D+ LL Sbjct: 169 QNDLYEIRLGEHRISTEEDCRQQGRKKKCAP-PVVNVGIEKHLIHEKYDARHIMHDIALL 227 Query: 125 RLSKPADITDVVKPIALP-TKEPKPGSKCLAS----GWGSITPTRWQKPDDLQCVFITLL 179 +L++ +KPI LP T E K ++ +++ GWG T D L + L Sbjct: 228 KLNRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWG--TTENGSSSDVLLQANVPLQ 285 Query: 180 PNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG----------ILQGTTSY 229 P C++ Y + V LC G G +D+C+ DSGGPL + G S Sbjct: 286 PRSACSQAYRRAVPLSQLCVGG-GDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQ 344 Query: 230 GPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 G V CG+ +P +YTN+ ++ WI DTM N Sbjct: 345 GVVTCGQISLPGLYTNVGEYVQWITDTMASNG 376 >1BRU-P nrPDB Length = 241 Score = 114 bits (285), Expect = 5e-26, Method: Compositional matrix adjust. Identities = 84/252 (33%), Positives = 120/252 (47%), Gaps = 27/252 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYY----QKEHICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKN 78 VVGG + + NS PWQV++ Y Q H CGG L+D++WVLTAAHC Y V LG++ Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 L EP + VSK H +N + L ND+ LL+L+ P +TD ++ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQL---------SNGNDIALLKLASPVSLTDKIQL 111 Query: 139 IALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQKVTD 194 LP C +GWG + T PD LQ + ++ C+K + V Sbjct: 112 GCLPAAGTILPNNYVCYVTGWGRL-QTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDGI-----LQGTTSYG-PVPCGKPGVPAIYTNLIK 248 M+CAG G +C DSGGPL C G + G S+G + C P+++T + Sbjct: 171 NMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 249 FNSWIKDTMMKN 260 + WI + N Sbjct: 230 YIDWINSVIANN 241 >4Z6A-H nrPDB Length = 249 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 77/248 (31%), Positives = 121/248 (48%), Gaps = 29/248 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVW------LGKN 78 +VGG C K PWQV + +CGG L++ WV++AAHC+ D+ + W LG++ Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCF-DKIKNWRNLIAVLGEH 59 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 L + + Q R V++ +++ T PG ++D+ LLRL +P +TD V P Sbjct: 60 DLSEHDGDEQSRRVAQ----------VIIPSTYVPGTT-NHDIALLRLHQPVVLTDHVVP 108 Query: 139 IALPTKEPKPGSKC-----LASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT 193 + LP + + L SGWG + R +L + + L ++C Y K+T Sbjct: 109 LCLPERTFSERTLAFVRFSLVSGWGQLL-DRGATALELMVLNVPRLMTQDCEASYPGKIT 167 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 + M CAG G KD+C+ DSGGP L G S+G C G +YT + ++ Sbjct: 168 EYMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWGQ-GCATVGHFGVYTRVSQY 226 Query: 250 NSWIKDTM 257 W++ M Sbjct: 227 IEWLQKLM 234 >1A5I-A nrPDB Length = 265 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 84/265 (31%), Positives = 122/265 (46%), Gaps = 41/265 (15%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEH------ICGGVLLDRNWVLTAAHCYV-----DQ 70 Q GG S PWQ A++ Q +CGG+L+ WVLTAAHC+ DQ Sbjct: 11 QLHSTGGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQ 70 Query: 71 YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKP- 129 +V LG+ + Q V K H F+ ++ND+ LL+L Sbjct: 71 LKVVLGRTYRVKPGEEEQTFKVKKYIVHKEFDDDT-----------YNNDIALLQLKSDS 119 Query: 130 ---ADITDVVKPIALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 A +D V+ I LP + ++C SG+G + + L+ + L P+ C Sbjct: 120 PQCAQESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRC 179 Query: 185 AKVYL--QKVTDVMLCAGEMGGGK------DTCRDDSGGPLIC----DGILQGTTSYGPV 232 A +L + VT+ MLCAG+ G+ D C+ DSGGPL+C L G S+G V Sbjct: 180 APKFLFNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWG-V 238 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTM 257 CG+ VP +YT + + WI+D M Sbjct: 239 GCGEKDVPGVYTKVTNYLGWIRDNM 263 >2RDL-A nrPDB Length = 226 Score = 112 bits (279), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 77/242 (31%), Positives = 122/242 (50%), Gaps = 22/242 (9%) Query: 25 VVGGFNCKKNSQPWQ--VAVYYQKEHI--CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG C+ +++P+ + + + H+ C G L+ RN+V+TAAHC V LG + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK--P 138 +E + Q V K FPHP ++ L++ ND+MLL+L + A++T V P Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVL-----------NDIMLLKLKEKANLTLGVGTLP 109 Query: 139 IALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 I+ + PG C A GWG T D LQ V + +L + C K + + LC Sbjct: 110 ISAKSNSIPPGRVCRAVGWGR-TNVNEPPSDTLQEVKMRILDPQAC-KHFEDFHQEPQLC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G ++ + DSGGPL+C GI QG SY + KP P+++T + + WI + Sbjct: 168 VGNPKKIRNVYKGDSGGPLLCAGIAQGIASY-VLRNAKP--PSVFTRISHYRPWINKILR 224 Query: 259 KN 260 +N Sbjct: 225 EN 226 >3LC3-A nrPDB Length = 235 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 72/242 (29%), Positives = 120/242 (49%), Gaps = 23/242 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWL--GKNKLFQ 82 VVGG + K PWQV + + + CGG +++ W++TAAHC ++ + G++ + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 E + Q R V + PH +N ++ +++D+ LL L +P + V PI + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAI---------NKYNHDIALLELDEPLVLNSYVTPICIA 111 Query: 143 TKEP-----KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 197 KE K GS SGWG + + + LQ + + L+ C + + + M Sbjct: 112 DKEYTNIFLKFGSG-YVSGWGRVFH-KGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMF 169 Query: 198 CAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 CAG GG+D+C+ DSGGP + + L G S+G C G IYT + ++ +WI Sbjct: 170 CAGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAMKGKYGIYTKVSRYVNWI 228 Query: 254 KD 255 K+ Sbjct: 229 KE 230 >4Q7Y-A nrPDB Length = 250 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 116/245 (47%), Gaps = 20/245 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 80 ++GG +S+P+ +V + +H CGG LL WV++AAHC+ + V LG + L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 EP+ Q + HP ++ +ND+ LLRL+ A + V + Sbjct: 61 STAEPTQQVFGIDALTTHPDYHP-----------MTHANDICLLRLNGSAVLGPAVGLLR 109 Query: 141 LPTKEPKP---GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 197 LP + +P G++C +GWG ++ + P L + +L + C + +T ML Sbjct: 110 LPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 168 Query: 198 CAGEMGGGKDT-CRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 C + C DSGGPL+C G S+ + CG P P +YT + F +WI D Sbjct: 169 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 257 MMKNA 261 + +++ Sbjct: 229 VRRSS 233 >1BDA-A nrPDB Length = 265 Score = 110 bits (276), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 81/265 (30%), Positives = 124/265 (46%), Gaps = 41/265 (15%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEH------ICGGVLLDRNWVLTAAHCYVDQY---- 71 Q R+ GG S PWQ A++ + +CGG+L+ W+L+AAHC+ +++ Sbjct: 11 QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHH 70 Query: 72 -EVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRL---- 126 V LG+ Q V K H F+ + ND+ LL+L Sbjct: 71 LTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDT-----------YDNDIALLQLKSDS 119 Query: 127 SKPADITDVVKPIALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 S+ A + VV+ + LP + + ++C SG+G + L+ + L P+ C Sbjct: 120 SRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRC 179 Query: 185 AKVYL--QKVTDVMLCAGEMGGG------KDTCRDDSGGPLIC--DG--ILQGTTSYGPV 232 +L + VTD MLCAG+ G D C+ DSGGPL+C DG L G S+G + Sbjct: 180 TSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWG-L 238 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTM 257 CG+ VP +YT + + WI+D M Sbjct: 239 GCGQKDVPGVYTKVTNYLDWIRDNM 263 >2KAI-A nrPDB Length = 80 Score = 110 bits (275), Expect = 7e-25, Method: Composition-based stats. Identities = 46/80 (57%), Positives = 59/80 (73%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++GG C+KNS PWQVA+Y+ CGGVL++ WVLTAAHC D YEVWLG++ LF+ E Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 85 PSAQHRLVSKSFPHPGFNMS 104 +AQ V+ FPHPGFN+S Sbjct: 61 NTAQFFGVTADFPHPGFNLS 80 >4XDE-A nrPDB Length = 257 Score = 107 bits (266), Expect = 7e-24, Method: Compositional matrix adjust. Identities = 77/256 (30%), Positives = 116/256 (45%), Gaps = 34/256 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ-----YEVWLGKNK 79 VVGG + + P+ A+Y+ C G L+ WVLTAAHC D+ V LG+ + Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS-FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD-----ITD 134 Q V H F+ + +DL LLRL + AD ++ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSP-----------VSYQHDLALLRLQEDADGSCALLSP 110 Query: 135 VVKPIALPTKEPKPGSK--CLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQ 190 V+P++LP+ +P C +GWG + LQ + L E C+ V+ Sbjct: 111 YVQPVSLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS 170 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTSYGPVPCGKPGVPAIY 243 + MLCAG + GG D C+ DSGGPL+C+ LQG S+G CG P +Y Sbjct: 171 SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVY 229 Query: 244 TNLIKFNSWIKDTMMK 259 T++ + +WI++ + Sbjct: 230 TDVAYYLAWIREHTVS 245 >1FIZ-A nrPDB Length = 263 Score = 106 bits (264), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 76/264 (28%), Positives = 124/264 (46%), Gaps = 39/264 (14%) Query: 25 VVGGFNCKKNSQPW----QVAVYY--QKEHICGGVLLDRNWVLTAAHCY-----VDQYEV 73 VVGG + + + PW Q+ +Y+ ++ H CGG+LL+ +WVLTAAHC+ V + + Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 74 WLGKNKLFQE-----EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 G N++ +P Q R V + H + L + ND+ L++++ Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEI-----------NDIALIKITP 109 Query: 129 PADITDVVKPIALPTKE---PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNE--N 183 P + P LP + P+ C +GWG + + LQ + L+ E N Sbjct: 110 PVPCGPFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCN 169 Query: 184 CAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG------ILQGTTSYGPVPCGKP 237 + Y ++ +CAG G DTC+ DSGGPL+C ++ G TS+G V C + Sbjct: 170 STRWYNGRIRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWG-VGCARA 228 Query: 238 GVPAIYTNLIKFNSWIKDTMMKNA 261 P +YT+ + +WI + NA Sbjct: 229 KRPGVYTSTWPYLNWIASKIGSNA 252 >1SC8-U nrPDB Length = 262 Score = 105 bits (262), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 70/254 (27%), Positives = 119/254 (46%), Gaps = 32/254 (12%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKE-----HICGGVLLDRNWVLTAAHCYVD-----QYEV 73 +++GG +QPW A+Y + ++CGG L+ WV++A HC++D Y V Sbjct: 15 KIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIV 74 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS----KP 129 +LG+++L V H ++ L ND+ LL++ + Sbjct: 75 YLGRSRLNSNTQGEMKFEVENLILHKDYSADTLA---------HHNDIALLKIRSKEGRC 125 Query: 130 ADITDVVKPIALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK- 186 A + ++ I+LP+ +P+ G+ C +G+G T + P+ L+ + L+ + C + Sbjct: 126 AQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQLKMTVVKLISHRECQQP 185 Query: 187 -VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPA 241 Y +VT MLCA + D+C+ DSGGPL+C L G S+G C P Sbjct: 186 HYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGR-GCALKDKPG 244 Query: 242 IYTNLIKFNSWIKD 255 +YT + F WI+ Sbjct: 245 VYTRVSHFLPWIRS 258 >1FUJ-A nrPDB Length = 221 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 73/246 (29%), Positives = 119/246 (48%), Gaps = 39/246 (15%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYVD----QYEVWLGK 77 +VGG + +S+P+ ++ + H CGG L+ ++VLTAAHC D V LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 + + +EP+ QH F+++ + L + ND++L++LS PA+++ V Sbjct: 61 HNVRTQEPTQQH-----------FSVAQVFLNNYD-AENKLNDILLIQLSSPANLSASVA 108 Query: 138 PIALPTK-EPKP-GSKCLASGWGSIT----PTRWQKPDDLQCVFITLLPNENCAKVYLQK 191 + LP + +P P G++CLA GWG + P + + ++ V P+ C V +K Sbjct: 109 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPPAQVLQELNVTVVTFFCRPHNICTFVPRRK 168 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNS 251 C DSGGPLICDGI+QG S+ C P +T + + Sbjct: 169 --------------AGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVD 214 Query: 252 WIKDTM 257 WI+ T+ Sbjct: 215 WIRSTL 220 >3F6U-H nrPDB Length = 240 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 72/246 (29%), Positives = 119/246 (48%), Gaps = 29/246 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHI-CGGVLLDRNWVLTAAHCYVDQYE--VWLGKNKLF 81 ++ G ++ PWQV + K+ + CG VL+ +WVLTAAHC + + V LG+ L Sbjct: 1 LIDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLR 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + E + + F HP ++ S ND+ LL L++PA ++ + PI L Sbjct: 61 RWEKWELDLDIKEVFVHPNYSKSTT-----------DNDIALLHLAQPATLSQTIVPICL 109 Query: 142 P------TKEPKPGSKCLASGWGSITPTRWQKPDD----LQCVFITLLPNENCAKVYLQK 191 P + + G + L +GWG + + + L + I ++P+ C++V Sbjct: 110 PDSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNM 169 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLI 247 V++ MLCAG +G +D C DSGGP++ L G S+G CG +YT + Sbjct: 170 VSENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGE-GCGLLHNYGVYTKVS 228 Query: 248 KFNSWI 253 ++ WI Sbjct: 229 RYLDWI 234 >1YC0-A nrPDB Length = 283 Score = 104 bits (259), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 75/254 (29%), Positives = 115/254 (45%), Gaps = 29/254 (11%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEVWL 75 L+ R++GG + S PW A+Y + C G L+ WV++AAHC+ D V L Sbjct: 32 LRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVL 90 Query: 76 GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV 135 G++ + Q + K P+ L ++ +D +DL+L+RL K D Sbjct: 91 GQHFFNRTTDVTQTFGIEKYIPY--------TLYSVFNPSD--HDLVLIRLKKKGDRCAT 140 Query: 136 VKPIALPTKEPKPGS------KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KV 187 P P+PGS KC +GWG + L+ + L+ + C+ +V Sbjct: 141 RSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEV 200 Query: 188 YLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIY 243 Y ++ MLCAG D C+ DSGGPL C+ L G S+G CG+ P +Y Sbjct: 201 YGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVY 259 Query: 244 TNLIKFNSWIKDTM 257 T + + WI D + Sbjct: 260 TRVANYVDWINDRI 273 >2V35-A nrPDB Length = 240 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 79/252 (31%), Positives = 123/252 (48%), Gaps = 28/252 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVDQ---YEVWLGK 77 VVGG ++NS P Q+++ Y+ H CGG L+ +NWV+TAAHC VD+ + V +G+ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHC-VDRELTFRVVVGE 59 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 + L Q + + Q+ V K HP +N T A + D+ LLRL++ + V+ Sbjct: 60 HNLNQNDGTEQYVGVQKIVVHPYWN-------TDDVAAGY--DIALLRLAQSVTLNSYVQ 110 Query: 138 PIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKVYLQKVT 193 LP S C +GWG +T T Q LQ ++ + C + + V Sbjct: 111 LGVLPRAGTILANNSPCYITGWG-LTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVK 169 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSY-GPVPCGKPGVPAIYTNLIK 248 + M+CAG G + C+ DSGGPL C + G TS+ + C P ++T + Sbjct: 170 NSMVCAGG-DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSA 228 Query: 249 FNSWIKDTMMKN 260 + SWI + + N Sbjct: 229 YISWINNVIASN 240 >4IGD-A nrPDB Length = 406 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 75/262 (28%), Positives = 119/262 (45%), Gaps = 42/262 (16%) Query: 21 LQSRVVGGFNCKKNSQPWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYVDQ--------- 70 L +++ G +K + PW + + + CGG LL +W++TAAHC Sbjct: 152 LMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPEDPTLR 211 Query: 71 ---------YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDL 121 +++ LGK+ + + + QH V + HP ++ + F ND+ Sbjct: 212 DSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNT-----------FENDV 260 Query: 122 MLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPN 181 L+ L + + V PI LP + G+ + SGWG R+ P+ L + I ++ + Sbjct: 261 ALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDH 318 Query: 182 ENCAKVYL---QKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPV 232 C K Y +KVT M+CAGE GGKD C DSGGP++ L GT S+G Sbjct: 319 STCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD- 377 Query: 233 PCGKPGVPAIYTNLIKFNSWIK 254 CGK +Y+ + WI+ Sbjct: 378 DCGKKDRYGVYSYIHHNKDWIQ 399 >1MKW-K nrPDB Length = 308 Score = 103 bits (257), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 77/270 (28%), Positives = 122/270 (45%), Gaps = 45/270 (16%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------V 68 ++ R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC V Sbjct: 46 IEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 69 DQYEVWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 D V +GK+ + E + ++ K + HP +N + D+ LL+L Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLK 155 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFI 176 +P +++D + P+ LP K+ G K +GWG+ T W +P LQ V + Sbjct: 156 RPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET-WTTSVAEVQPSVLQVVNL 214 Query: 177 TLLPNENCAKVYLQKVTDVMLCAG-EMGGGK--DTCRDDSGGPLICDG------ILQGTT 227 L+ C ++TD M CAG + G GK D C DSGGP + G Sbjct: 215 PLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIV 274 Query: 228 SYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 S+G C + G YT++ + WI+ + Sbjct: 275 SWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 303 >1ELT-A nrPDB Length = 236 Score = 103 bits (257), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 80/249 (32%), Positives = 116/249 (46%), Gaps = 29/249 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVDQYEVW---LGK 77 VVGG + NS PWQ+++ Y+ H CGG L+ + WV+TAAHC VD W LG+ Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHC-VDSARTWRVVLGE 59 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 + L E Q V+ F H G+N + G D+ LLRL+ A + V+ Sbjct: 60 HNLNTNEGKEQIMTVNSVFIHSGWNS-----DDVAGGY----DIALLRLNTQASLNSAVQ 110 Query: 138 PIAL-PTKEPKPGSK-CLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV--YLQKVT 193 AL P+ + P + C +GWG T T D L+ ++ + + C+ + V Sbjct: 111 LAALPPSNQILPNNNPCYITGWGK-TSTGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVK 169 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSY-GPVPCGKPGVPAIYTNLIK 248 M+CAG GG C DSGGPL C + G TS+ C P ++T + Sbjct: 170 TTMVCAG--GGANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSA 227 Query: 249 FNSWIKDTM 257 + SW+ M Sbjct: 228 YISWMNGIM 236 >3RP2-A nrPDB Length = 224 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/239 (30%), Positives = 112/239 (46%), Gaps = 22/239 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEH----ICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG +S+P+ + E ICGG L+ R +VLTAAHC + V LG + + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + E + Q V K H +N ++P +D+MLL+L K ++T V + Sbjct: 61 RKRESTQQKIKVEKQIIHESYN-------SVPN----LHDIMLLKLEKKVELTPAVNVVP 109 Query: 141 LPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 LP+ PG+ C A+GWG T R L+ V + ++ + C Y +C Sbjct: 110 LPSPSDFIHPGAMCWAAGWGK-TGVRDPTSYTLREVELRIMDEKACVD-YRYYEYKFQVC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G + DSGGPL+C G+ G SYG P KP PAI+T + + WI + Sbjct: 168 VGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYGH-PDAKP--PAIFTRVSTYVPWINAVI 223 >4DJZ-B nrPDB Length = 251 Score = 102 bits (254), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 74/258 (28%), Positives = 116/258 (44%), Gaps = 42/258 (16%) Query: 25 VVGGFNCKKNSQPWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYVDQ------------- 70 + G +K + PW + + + CGG LL +W++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 71 -----YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLR 125 +++ LGK+ + + + QH V + HP ++ + F ND+ L+ Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNT-----------FENDVALVE 109 Query: 126 LSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 L + + V PI LP + G+ + SGWG R+ P+ L + I ++ + C Sbjct: 110 LLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQRF--PETLMEIEIPIVDHSTCQ 167 Query: 186 KVYL---QKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPCGK 236 K Y +KVT M+CAGE GGKD C DSGGP++ L GT S+G CGK Sbjct: 168 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGK 226 Query: 237 PGVPAIYTNLIKFNSWIK 254 +Y+ + WI+ Sbjct: 227 KDRYGVYSYIHHNKDWIQ 244 >4MPW-A nrPDB Length = 245 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 79/258 (30%), Positives = 118/258 (45%), Gaps = 36/258 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE---HICGGVLLDRNWVLTAAHCY-VDQYEVWLGKNKL 80 +VGG ++ PWQV++ H CGG L+ WVLTAAHC D ++ + +L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 81 FQEEPSAQHRL--VSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 ++ Q +L VS+ HP F A D+ LL L +P ++ V Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQFYT-----------AQIGADIALLELEEPVKVSSHVHT 109 Query: 139 IALP--TKEPKPGSKCLASGWGSI-TPTRWQKPDDLQCVFITLLPNENCAKVY------- 188 + LP ++ PG C +GWG + R P L+ V + ++ N C Y Sbjct: 110 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 169 Query: 189 --LQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAI 242 ++ V D MLCAG +D+C+ DSGGPL+C + G S+G C +P P I Sbjct: 170 DDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGI 226 Query: 243 YTNLIKFNSWIKDTMMKN 260 YT + + WI + K Sbjct: 227 YTRVTYYLDWIHHYVPKK 244 >1Q3X-A nrPDB Length = 328 Score = 102 bits (253), Expect = 2e-22, Method: Compositional matrix adjust. Identities = 80/263 (30%), Positives = 113/263 (42%), Gaps = 38/263 (14%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------ 70 +A R+ GG K PWQV + G LL NWVLTAAH +Q Sbjct: 79 SARTTGGRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASA 136 Query: 71 YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 ++ +G K P F H G+ A F ND+ L++L+ Sbjct: 137 LDIRMGTLKRLS--PHYTQAWSEAVFIHEGYTHD----------AGFDNDIALIKLNNKV 184 Query: 131 DITDVVKPIALPTKEPKPGSKC----LASGWGSITPTRWQKPDDLQCVFITLLPNENCAK 186 I + PI LP KE + + ASGWG R +L V I ++ ++ C Sbjct: 185 VINSNITPICLPRKEAESFMRTDDIGTASGWG--LTQRGFLARNLMYVDIPIVDHQKCTA 242 Query: 187 VYLQ------KVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPC 234 Y + VT MLCAG GGKD+CR DSGG L+ + G S+G + C Sbjct: 243 AYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNC 302 Query: 235 GKPGVPAIYTNLIKFNSWIKDTM 257 G+ G +YT +I + WI++ + Sbjct: 303 GEAGQYGVYTKVINYIPWIENII 325 >2OQ5-A nrPDB Length = 232 Score = 101 bits (251), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 68/240 (28%), Positives = 109/240 (45%), Gaps = 25/240 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--VWLGKNKLFQ 82 +VGG ++ PWQ ++ + H CG L++ W+++AAHC+ W + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGV-T 59 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 +PS R + + H + P D+ D+ L LS P T+ V + LP Sbjct: 60 IKPSKMKRGLRRIIVHEKYKH---------PSHDY--DISLAELSSPVPYTNAVHRVCLP 108 Query: 143 --TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KVYLQKVTDVMLC 198 + E +PG +G+G++ + + + L+ +TL+ C + Y +T MLC Sbjct: 109 DASYEFQPGDVMFVTGFGALKNDGYSQ-NHLRQAQVTLIDATTCNEPQAYNDAITPRMLC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 AG + G D C+ DSGGPL+ L G S+G C KP P +YT + WI Sbjct: 168 AGSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGD-ECAKPNKPGVYTRVTALRDWI 226 >5XW8-A nrPDB Length = 133 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 50/136 (36%), Positives = 76/136 (55%), Gaps = 12/136 (8%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQE 83 ++VGG+ C NS P+QV++ H CGG L++ WV++AAHCY + +V LG++ + Sbjct: 8 KIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNIDVL 66 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 E + Q +K HP FN G ND+ML++LS PA + V ++LP Sbjct: 67 EGNEQFINAAKIITHPNFN-----------GNTLDNDIMLIKLSSPATLNSRVATVSLPR 115 Query: 144 KEPKPGSKCLASGWGS 159 G++CL SGWG+ Sbjct: 116 SCAAAGTECLISGWGN 131 >2XRC-A nrPDB Length = 565 Score = 101 bits (251), Expect = 4e-22, Method: Compositional matrix adjust. Identities = 76/266 (28%), Positives = 112/266 (42%), Gaps = 35/266 (13%) Query: 6 LFLALSLGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAH 65 L LS G + + R+VGG + PWQVA+ CGG+ + W+LTAAH Sbjct: 303 LLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAH 362 Query: 66 CY----VDQYEVWLGKNKLFQEEPSAQH---RLVSKSFPHPGFNMSLLMLQTIPPGADFS 118 C +Y++W P + V + H +N + Sbjct: 363 CLRASKTHRYQIWTTVVDWIH--PDLKRIVIEYVDRIIFHENYN-----------AGTYQ 409 Query: 119 NDLMLLRLSKPADITDVVKPIALPTKEP------KPGSKCLASGWGSITPTRWQKPDDLQ 172 ND+ L+ + K + D P ++P P +P C+ SGWG ++ LQ Sbjct: 410 NDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQ 467 Query: 173 CVFITLLPNENCAKVYLQKVTD-VMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGP 231 + L+ NC+K Y + + M CAG G D C+ DSGGPL+C T +G Sbjct: 468 WGEVKLIS--NCSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGV 525 Query: 232 VP----CGKPGVPAIYTNLIKFNSWI 253 V CGKP P +YT + + WI Sbjct: 526 VSWGENCGKPEFPGVYTKVANYFDWI 551 >1EQ9-A nrPDB Length = 222 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 76/241 (31%), Positives = 114/241 (47%), Gaps = 25/241 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY-----VDQYEVWLGKNK 79 +VGG + P+QV++ H CG +LD N VLTAAHC +++ +V +G N Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L + S V + + ++ LL ND+ L+ L+ P D+V+PI Sbjct: 61 LSE---SGDVYDVEDAVVNKNYDDFLLR-----------NDVALVHLTNPIKFNDLVQPI 106 Query: 140 ALPTKEPKPGSK-CLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 L T + S C +GWGS T P+ LQ + + + P + C + +V D +C Sbjct: 107 KLSTNDEDLESNPCTLTGWGS-TRLGGNTPNALQEIELIVHPQKQCERDQW-RVIDSHIC 164 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G+ C DSGGPL+ +G G S+G PC G P +YT + F SWI + Sbjct: 165 T-LTKRGEGACHGDSGGPLVANGAQIGIVSFGS-PCAL-GEPDVYTRVSSFVSWINANLK 221 Query: 259 K 259 K Sbjct: 222 K 222 >2R0L-A nrPDB Length = 248 Score = 100 bits (250), Expect = 5e-22, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 112/250 (44%), Gaps = 29/250 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGKNK 79 ++GG + S PW A+Y + C G L+ WV++AAHC+ D V LG++ Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 + Q + K P+ L ++ +D +DL+L+RL K D Sbjct: 60 FNRTTDVTQTFGIEKYIPY--------TLYSVFNPSD--HDLVLIRLKKKGDRCATRSQF 109 Query: 140 ALPTKEPKPGS------KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KVYLQK 191 P P+PGS KC +GWG + L+ + L+ + C+ +VY Sbjct: 110 VQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD 169 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLI 247 ++ MLCAG D C+ DSGGPL C+ L G S+G CG+ P +YT + Sbjct: 170 ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVA 228 Query: 248 KFNSWIKDTM 257 + WI D + Sbjct: 229 NYVDWINDRI 238 >2OCV-B nrPDB Length = 259 Score = 100 bits (249), Expect = 6e-22, Method: Compositional matrix adjust. Identities = 73/266 (27%), Positives = 122/266 (45%), Gaps = 45/266 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV----------DQYE 72 +V G++ +K PWQV ++ + +E +CG L+ WVLTAAHC + + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + + ++ K + HP +N + D+ LL+L KP Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWR----------ENLDRDIALLKLKKPVP 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFITLLP 180 +D + P+ LP K+ + G K +GWG++ T W +P LQ V + ++ Sbjct: 111 FSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRET-WTTNINEIQPSVLQVVNLPIVE 169 Query: 181 NENCAKVYLQKVTDVMLCAG-EMGGGK--DTCRDDSGGPLICDGILQ------GTTSYGP 231 C ++TD M CAG ++ K D C DSGGP + G S+G Sbjct: 170 RPVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE 229 Query: 232 VPCGKPGVPAIYTNLIKFNSWIKDTM 257 C + G YT++ + +WI+ + Sbjct: 230 -GCDRKGKYGFYTHVFRLKAWIQKVI 254 >1ETT-H nrPDB Length = 259 Score = 100 bits (248), Expect = 7e-22, Method: Compositional matrix adjust. Identities = 76/266 (28%), Positives = 119/266 (44%), Gaps = 45/266 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC VD Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + ++ K + HP +N + D+ LL+L +P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFITLLP 180 ++D + P+ LP K+ G K +GWG+ T W +P LQ V + L+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET-WTTSVAEVQPSVLQVVNLPLVE 169 Query: 181 NENCAKVYLQKVTDVMLCAG-EMGGGK--DTCRDDSGGPLICDG------ILQGTTSYGP 231 C ++TD M CAG + G GK D C DSGGP + G S+G Sbjct: 170 RPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE 229 Query: 232 VPCGKPGVPAIYTNLIKFNSWIKDTM 257 C + G YT++ + WI+ + Sbjct: 230 -GCDRDGKYGFYTHVFRLKKWIQKVI 254 >3K65-B nrPDB Length = 308 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 71/270 (26%), Positives = 120/270 (44%), Gaps = 45/270 (16%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV---------- 68 + R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 46 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 105 Query: 69 DQYEVWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 106 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 155 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFI 176 KP +D + P+ LP +E + G K +GWG++ T W +P LQ V + Sbjct: 156 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET-WTANVGKGQPSVLQVVNL 214 Query: 177 TLLPNENCAKVYLQKVTDVMLCAG---EMGGGKDTCRDDSGGPLICDGILQ------GTT 227 ++ C ++TD M CAG + G D C D+GGP + G Sbjct: 215 PIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIV 274 Query: 228 SYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 S+G C + G YT++ + WI+ + Sbjct: 275 SWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 303 >3NXP-A nrPDB Length = 424 Score = 100 bits (248), Expect = 8e-22, Method: Compositional matrix adjust. Identities = 72/270 (26%), Positives = 120/270 (44%), Gaps = 45/270 (16%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV---------- 68 + R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 162 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 221 Query: 69 DQYEVWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 222 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 271 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFI 176 KP +D + P+ LP +E + G K +GWG++ T W +P LQ V + Sbjct: 272 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET-WTANVGKGQPSVLQVVNL 330 Query: 177 TLLPNENCAKVYLQKVTDVMLCAG---EMGGGKDTCRDDSGGPLICDGILQ------GTT 227 ++ C ++TD M CAG + G D C DSGGP + G Sbjct: 331 PIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIV 390 Query: 228 SYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 S+G C + G YT++ + WI+ + Sbjct: 391 SWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 419 >5LHN-A nrPDB Length = 247 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 72/256 (28%), Positives = 120/256 (46%), Gaps = 33/256 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE------HICGGVLLDRNWVLTAAHCYV-----DQYEV 73 +VGG + +QPW A+Y + + CGG L+ WV +AAHC++ + Y V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKP---- 129 +LG++K P V + H + L + ND+ LL++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLA---------YHNDIALLKIRTSTGQC 111 Query: 130 ADITDVVKPIALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK- 186 A + ++ IALP + + GS C +G+G + + + P +L+ + L+ +E C + Sbjct: 112 AQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQP 171 Query: 187 -VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPA 241 Y ++ MLCA + D+C+ DSGGPLIC+ L G S+G C + P Sbjct: 172 HYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWG-RGCAEKNKPG 230 Query: 242 IYTNLIKFNSWIKDTM 257 +YT + F WI+ + Sbjct: 231 VYTRVSHFLDWIQSHI 246 >1LTO-A nrPDB Length = 245 Score = 100 bits (248), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 80/257 (31%), Positives = 121/257 (47%), Gaps = 34/257 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE---HICGGVLLDRNWVLTAAHCY-VDQYEVWLGKNKL 80 +VGG ++ PWQV++ + H CGG L+ WVLTAAHC D ++ + +L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 81 FQEEPSAQHRL--VSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 ++ Q +L VS+ HP F ++QT GAD + LL L +P +I+ V Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQF----YIIQT---GADIA----LLELEEPVNISSRVHT 109 Query: 139 IALP--TKEPKPGSKCLASGWGSITPTR-WQKPDDLQCVFITLLPNENCAKVY------- 188 + LP ++ PG C +GWG + P L+ V + ++ N C Y Sbjct: 110 VMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 169 Query: 189 --LQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD---GILQGTTSYGPVPCGKPGVPAIY 243 ++ + D MLCAG +D+C+ DSGGPL+C LQ C +P P IY Sbjct: 170 DDVRIIRDDMLCAGN--SQRDSCKGDSGGPLVCKVNGTWLQAGVVSWDEGCAQPNRPGIY 227 Query: 244 TNLIKFNSWIKDTMMKN 260 T + + WI + K Sbjct: 228 TRVTYYLDWIHHYVPKK 244 >4FXG-H nrPDB Length = 242 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 77/255 (30%), Positives = 110/255 (43%), Gaps = 38/255 (14%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------YEVWLGKN 78 + GG K PWQV + G LL NWVLTAAH +Q ++ +G Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGTL 58 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 K P F H G+ A F ND+ L++L+ I + P Sbjct: 59 KRLS--PHYTQAWSEAVFIHEGYTHD----------AGFDNDIALIKLNNKVVINSNITP 106 Query: 139 IALPTKEPKPGSKC----LASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ---- 190 I LP KE + + ASGWG R +L V I ++ ++ C Y + Sbjct: 107 ICLPRKEAESFMRTDDIGTASGWG--LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPYP 164 Query: 191 --KVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPCGKPGVPAI 242 VT MLCAG GGKD+CR D+GG L+ + G S+G + CG+ G + Sbjct: 165 RGSVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGV 224 Query: 243 YTNLIKFNSWIKDTM 257 YT +I + WI++ + Sbjct: 225 YTKVINYIPWIENII 239 >4NZQ-A nrPDB Length = 557 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 72/270 (26%), Positives = 120/270 (44%), Gaps = 45/270 (16%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV---------- 68 + R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 295 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 69 DQYEVWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 404 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFI 176 KP +D + P+ LP +E + G K +GWG++ T W +P LQ V + Sbjct: 405 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET-WTANVGKGQPSVLQVVNL 463 Query: 177 TLLPNENCAKVYLQKVTDVMLCAG---EMGGGKDTCRDDSGGPLICDGILQ------GTT 227 ++ C ++TD M CAG + G D C DSGGP + G Sbjct: 464 PIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIV 523 Query: 228 SYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 S+G C + G YT++ + WI+ + Sbjct: 524 SWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 552 >1ZJK-A nrPDB Length = 403 Score = 99.0 bits (245), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 78/256 (30%), Positives = 111/256 (43%), Gaps = 38/256 (14%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------YEVWLGK 77 ++ GG K PWQV + G LL NWVLTAAH +Q ++ +G Sbjct: 161 QIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMGT 218 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 K P F H G+ A F ND+ L++L+ I + Sbjct: 219 LKRLS--PHYTQAWSEAVFIHEGYTHD----------AGFDNDIALIKLNNKVVINSNIT 266 Query: 138 PIALPTKEPKPGSKC----LASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ--- 190 PI LP KE + + ASGWG R +L V I ++ ++ C Y + Sbjct: 267 PICLPRKEAESFMRTDDIGTASGWG--LTQRGFLARNLMYVDIPIVDHQKCTAAYEKPPY 324 Query: 191 ---KVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPCGKPGVPA 241 VT MLCAG GGKD+CR DSGG L+ + G S+G + CG+ G Sbjct: 325 PRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYG 384 Query: 242 IYTNLIKFNSWIKDTM 257 +YT +I + WI++ + Sbjct: 385 VYTKVINYIPWIENII 400 >5O32-I nrPDB Length = 244 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 106/245 (43%), Gaps = 31/245 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLG-KNK 79 +VGG + PWQVA+ CGG+ + W+LTAAHC +Y++W + Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 + + V + H +N + ND+ L+ + K + D P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYN-----------AGTYQNDIALIEMKKDGNKKDCELPR 109 Query: 140 ALPTKEP------KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT 193 ++P P +P C+ SGWG ++ LQ + L+ NC+K Y + Sbjct: 110 SIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLI--SNCSKFYGNRFY 165 Query: 194 D-VMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVP----CGKPGVPAIYTNLIK 248 + M CAG G D C+ DSGGPL+C T +G V CGKP P +YT + Sbjct: 166 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGENCGKPEFPGVYTKVAN 225 Query: 249 FNSWI 253 + WI Sbjct: 226 YFDWI 230 >1FIW-A nrPDB Length = 290 Score = 98.6 bits (244), Expect = 2e-21, Method: Compositional matrix adjust. Identities = 74/266 (27%), Positives = 117/266 (43%), Gaps = 43/266 (16%) Query: 25 VVGGFNCKKNSQPW----QVAVYY--QKEHICGGVLLDRNWVLTAAHCY----------- 67 ++GG + + PW Q+ Y+ ++ H+CGG LL+ W+LTAAHC+ Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 68 -VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRL 126 EV G NK + P Q R V K H ++ S +ND+ L+++ Sbjct: 61 IFGAKEVEWGTNKPVK--PPLQERYVEKIIIHEKYSAS-----------SEANDIALMKI 107 Query: 127 SKPADITDVVKPIALPTKE---PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNE- 182 + P + P LP P+ C +GWG + + LQ + L+ Sbjct: 108 TPPVTCGHFIGPGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGL 167 Query: 183 -NCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG------ILQGTTSYGPVPCG 235 N + Y ++ +CAG G DTC+ DSGGPL+C ++ G TS+G V C Sbjct: 168 CNSTRWYNGRIRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWG-VGCA 226 Query: 236 KPGVPAIYTNLIKFNSWIKDTMMKNA 261 + P +YT+ + +WI + A Sbjct: 227 RAKRPGVYTSTWSYLNWIASKIGSTA 252 >1PQ7-A nrPDB Length = 224 Score = 98.2 bits (243), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 71/233 (30%), Positives = 106/233 (45%), Gaps = 17/233 (7%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG + P+ V++ CGG LL+ N VLTAAHC V Y + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHC-VSGYA-----------Q 48 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK--PADITDVVKPIALP 142 Q R S S G SL ++ P + +NDL +L+LS P+ +A Sbjct: 49 SGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLSTSIPSGGNIGYARLAAS 108 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY-LQKVTDVMLCAGE 201 +P GS +GWG+ + P +L V + ++ C Y +T+ M CAG Sbjct: 109 GSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGV 168 Query: 202 MGGGKDTCRDDSGGPLI-CDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 GGKD+C+ DSGGP++ L G S+G C +P +Y ++ S+I Sbjct: 169 SSGGKDSCQGDSGGPIVDSSNTLIGAVSWGN-GCARPNYSGVYASVGALRSFI 220 >4H4F-A nrPDB Length = 249 Score = 97.4 bits (241), Expect = 5e-21, Method: Compositional matrix adjust. Identities = 79/251 (31%), Positives = 122/251 (48%), Gaps = 32/251 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKN 78 VVGG + + +S PWQ+++ Y K H CGG L+ N+VLTAAHC + Y V +GKN Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 KL-FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 L ++E + V H +N LL ND+ L++L++ +++D ++ Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLL-----------RNDIALIKLAEHVELSDTIQ 109 Query: 138 PIALPTKE---PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV--YLQKV 192 LP K+ PK C +GWG + T D LQ ++ + C+++ + +V Sbjct: 110 VACLPEKDSLLPKD-YPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRV 167 Query: 193 TDVMLCAGEMGGGKDTCRDDSGGPLIC---DGILQ--GTTSYGPVP-CGKPGVPAIYTNL 246 M+CAG G C DSGGPL C +G + G S+G C P +YT + Sbjct: 168 KKTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRV 226 Query: 247 IKFNSWIKDTM 257 + WI + M Sbjct: 227 SAYIDWINEKM 237 >1PYT-D nrPDB Length = 251 Score = 96.7 bits (239), Expect = 9e-21, Method: Compositional matrix adjust. Identities = 77/255 (30%), Positives = 123/255 (48%), Gaps = 29/255 (11%) Query: 19 PPLQSRVVGGFNCKKNSQPWQVAVYYQKE----HICGGVLLDRNWVLTAAHCYVD--QYE 72 P L +RVVGG + +S PWQ+++ Y ++ H CGG L+ N VLTAAHC + Y Sbjct: 8 PNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCISNTLTYR 67 Query: 73 VWLGKNKL-FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V LGKN L ++E + + V F H +N L+ ND+ L++L++ + Sbjct: 68 VALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLV-----------RNDIALIKLAETVE 116 Query: 132 ITDVVKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV-- 187 + D ++ LP++ C +GWG + T +LQ ++ C++ Sbjct: 117 LGDTIQVACLPSEGSLLPQDYPCFVTGWGRLY-TNGPIAAELQQGLQPVVDYATCSQRDW 175 Query: 188 YLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC--DGI--LQGTTSYGP-VPCGKPGVPAI 242 + V + M+CAG G C DSGGPL C DG ++G S+G + C P + Sbjct: 176 WGTTVKETMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCNTFKKPTV 234 Query: 243 YTNLIKFNSWIKDTM 257 +T + + WI + Sbjct: 235 FTRVSAYIDWINQKL 249 >1AE5-A nrPDB Length = 225 Score = 95.5 bits (236), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 69/243 (28%), Positives = 111/243 (45%), Gaps = 31/243 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 80 +VGG + P+ ++ Q H CGG L+ +V+TAA C+ Q V LG L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + E ++ S G++ P + NDLMLL+L + A++T V + Sbjct: 61 RRRERQSRQTFSISSMSENGYD----------PQQNL-NDLMLLQLDREANLTSSVTILP 109 Query: 141 LPTKEP--KPGSKCLASGWGS-ITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 197 LP + + G++C +GWGS + R + V +T+ P + C + +V Sbjct: 110 LPLQNATVEAGTRCQVAGWGSQRSGGRLSRFPRF--VNVTVTPEDQC------RPNNV-- 159 Query: 198 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 C G + C D G PL+C+G+ G S+ PCG+ P +T + F WI D + Sbjct: 160 CTGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWI-DGV 216 Query: 258 MKN 260 + N Sbjct: 217 LNN 219 >4KKD-A nrPDB Length = 433 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 79/285 (27%), Positives = 123/285 (43%), Gaps = 59/285 (20%) Query: 19 PPLQSRVVGGFNCKKNSQPWQVAVYYQKEH-------ICGGVLLDRNWVLTAAHCYVDQY 71 P L R++GG N + PWQ + + G LL +W+LTAAH Q Sbjct: 149 PSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQR 208 Query: 72 E-------------VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFS 118 V+LG + + +++ A + ++ HP FN+ +++ Sbjct: 209 RDTTVIPVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQ-----------NYN 256 Query: 119 NDLMLLRLSKPADITDVVKPIALPTKEPK---PGSKCLASGWGSITP-----------TR 164 +D+ L++L +P + V P+ LP EP+ P L +GWG P TR Sbjct: 257 HDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTR 316 Query: 165 WQKPDDLQCVFITLLPNENCAKVYLQK-----VTDVMLCAGEMGGGKDTCRDDSGGPLIC 219 D LQ V + ++P+ C Y + VT+ M CAG GGKDTC DSG + Sbjct: 317 -TLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAFVI 375 Query: 220 ------DGILQGTTSY-GPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 ++QG S+ GP CG V +YT + + W+ + M Sbjct: 376 FDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 420 >4IW4-E nrPDB Length = 279 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 77/279 (27%), Positives = 121/279 (43%), Gaps = 59/279 (21%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEH-------ICGGVLLDRNWVLTAAHCYVDQYE----- 72 ++GG N + PWQ + + G LL +W+LTAAH Q Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 73 --------VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLL 124 V+LG + + +++ A + ++ HP FN+ ++++D+ L+ Sbjct: 61 PVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQ-----------NYNHDIALV 108 Query: 125 RLSKPADITDVVKPIALPTKEPK---PGSKCLASGWGSITP-----------TRWQKPDD 170 +L +P + V P+ LP EP+ P L +GWG P TR D Sbjct: 109 QLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTR-TLSDV 167 Query: 171 LQCVFITLLPNENCAKVYLQK-----VTDVMLCAGEMGGGKDTCRDDSGGPLIC------ 219 LQ V + ++P+ C Y + VT+ M CAG GGKDTC DSGG + Sbjct: 168 LQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQ 227 Query: 220 DGILQGTTSY-GPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 ++QG S+ GP CG V +YT + + W+ + M Sbjct: 228 RWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQM 266 >5TO3-B nrPDB Length = 409 Score = 94.0 bits (232), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 71/266 (26%), Positives = 117/266 (43%), Gaps = 45/266 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV----------DQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + + ++ K + HP +N + D+ L++L KP Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFITLLP 180 +D + P+ LP +E + G K +GWG++ T W +P LQ V + ++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET-WTANVGKGQPSVLQVVNLPIVE 169 Query: 181 NENCAKVYLQKVTDVMLCAG---EMGGGKDTCRDDSGGPLICDGILQ------GTTSYGP 231 C ++TD M CAG + G D C DSGGP + G S G Sbjct: 170 RPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAG- 228 Query: 232 VPCGKPGVPAIYTNLIKFNSWIKDTM 257 C + G YT++ + WI+ + Sbjct: 229 AGCDRDGKYGFYTHVFRLKKWIQKVI 254 >2ZKS-A nrPDB Length = 240 Score = 94.0 bits (232), Expect = 6e-20, Method: Compositional matrix adjust. Identities = 67/248 (27%), Positives = 112/248 (45%), Gaps = 27/248 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD---QYEVWLGKNKLF 81 ++GG +S+P+ ++ H+CGGVL+ WVLTAAHC Q + LG + L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTL- 59 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + P + + HP + P NDL LL+L + ++P+AL Sbjct: 60 -DSPGLTFH-IKAAIQHPRYK----------PVPALENDLALLQLDGKVKPSRTIRPLAL 107 Query: 142 PTKEP--KPGSKCLASGWGSITP----TRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV 195 P+K G++C +GWG +R + DLQ + + N ++ + ++ Sbjct: 108 PSKRQVVAAGTRCSMAGWGLTHQGGRLSRVLRELDLQVLDTRMCNN---SRFWNGSLSPS 164 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDG--ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 M+C + C+ DSGGPL+C +L G S+ C P + T + + SWI Sbjct: 165 MVCLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWI 224 Query: 254 KDTMMKNA 261 + ++A Sbjct: 225 RKVTGRSA 232 >1VR1-H nrPDB Length = 261 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 69/270 (25%), Positives = 116/270 (42%), Gaps = 49/270 (18%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ------KEHICGGVLLDRNWVLTAAHCYV---------- 68 +V G + + PWQV ++ + + +CG L+ WVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 DQYEVWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 110 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPTRWQ------KPDDLQCVFI 176 KP +D + P+ LP +E + G K +GWG++ T W +P LQ V + Sbjct: 111 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET-WTANVGKGQPSVLQVVNL 169 Query: 177 TLLPNENCAKVYLQKVTDVMLCAG---EMGGGKDTCRDDSGGPLICDGILQ------GTT 227 ++ C ++TD M CA + G D C DSGGP + G Sbjct: 170 PIVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIV 229 Query: 228 SYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 S+G C + G YT++ + WI+ + Sbjct: 230 SWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 258 >1SI5-H nrPDB Length = 240 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 70/245 (28%), Positives = 110/245 (44%), Gaps = 29/245 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLGKNKL 80 VV G + N W V++ Y+ +HICGG L+ +WVLTA C+ + YE WLG + + Sbjct: 1 VVNGIPTRTNIG-WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDV 59 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 ++ N+S L+ P G+ DL+L++L++PA + D V I Sbjct: 60 HGRGDEKCKQV---------LNVSQLVYG--PEGS----DLVLMKLARPAVLDDFVSTID 104 Query: 141 LPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT--DVM 196 LP + C GWG + L+ + ++ NE C++ + KVT + Sbjct: 105 LPNYGSTIPEKTSCSVYGWGYTGLINYDGL--LRVAHLYIMGNEKCSQHHRGKVTLNESE 162 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVP---CGKPGVPAIYTNLIKFNSWI 253 +CAG G C D GGPL+C+ VP C P P I+ + + WI Sbjct: 163 ICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGRGCAIPNRPGIFVRVAYYAKWI 222 Query: 254 KDTMM 258 ++ Sbjct: 223 HKIIL 227 >1FON-A nrPDB Length = 240 Score = 90.9 bits (224), Expect = 6e-19, Method: Compositional matrix adjust. Identities = 79/244 (32%), Positives = 115/244 (47%), Gaps = 30/244 (12%) Query: 35 SQPWQVAVYYQKE----HICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKNKLFQEEPSAQ 88 S WQV++ Y+K+ H CGG L+ +WV+TA HC Y+V LG+ E S Q Sbjct: 9 SWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDRSVLEGSEQ 68 Query: 89 HRLVSKS--FPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL-PTKE 145 ++ F HP +N + + ND+ L++LS+ A + D V+ L P + Sbjct: 69 VIPINAGDLFVHPLWNSNCVAC---------GNDIALVKLSRSAQLGDKVQLANLPPAGD 119 Query: 146 PKPGSK-CLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT--DVMLCAGEM 202 P C SGWG + T PD LQ + + E+C++ +T M+CAG Sbjct: 120 ILPNEAPCYISGWGRLY-TGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKKTMVCAG-- 176 Query: 203 GGGKDTCRDDSGGPLIC---DGILQ--GTTSY-GPVPCGKPGVPAIYTNLIKFNSWIKDT 256 G + C DSGGPL C DG Q G TS+ C P ++T + F WI +T Sbjct: 177 GDTRSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSAFIDWIDET 236 Query: 257 MMKN 260 + N Sbjct: 237 IASN 240 >5KWM-A nrPDB Length = 230 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 71/233 (30%), Positives = 103/233 (44%), Gaps = 27/233 (11%) Query: 25 VVGGFNCKKNSQPWQVA-VYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNK 79 +VGG + P+ VA V + CGG L N V+TAAHC V V G+ Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 + E + V+ + HP + Q G D S +L L P PI Sbjct: 61 MSSNEGTVSK--VTNVWVHPEY-------QDAAKGFDVS----VLTLEAPVK----EAPI 103 Query: 140 ALPTKEPK---PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 L + P + GWG+ T Q+ D LQ + + ++ C + Y + D M Sbjct: 104 ELAKADDAGYAPDTAATILGWGN-TSEGGQQADHLQKATVPVNSDDTCKQAYGEYTPDAM 162 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 +CAG GG DTC+ DSGGP++ + L G TS+G C +PG P +Y + + Sbjct: 163 VCAGVPEGGVDTCQGDSGGPMVVNNKLIGVTSWGE-GCARPGKPGVYARVGAY 214 >1KIG-H nrPDB Length = 241 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 70/249 (28%), Positives = 105/249 (42%), Gaps = 25/249 (10%) Query: 25 VVGGFNCKKNSQPWQ-VAVYYQKEHICGGVLLDRNWVLTAAHCY--VDQYEVWLGKNKLF 81 +VGG +C + PWQ + V + E CGG +L+ +VLTAAHC ++ V +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 QEE + V + H F + DF D+ +LRL P V P L Sbjct: 61 QEEGNEMAHEVEMTVKHSRF---------VKETYDF--DIAVLRLKTPIRFRRNVAPACL 109 Query: 142 PTKEPKPGS-----KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 P K+ + + SG+G T + + L+ + + + C +T M Sbjct: 110 PEKDWAEATLMTQKTGIVSGFGR-THEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNM 168 Query: 197 LCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSW 252 CAG +D C+ DSGGP + + G S+G C + G +YT + F W Sbjct: 169 FCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKFGVYTKVSNFLKW 227 Query: 253 IKDTMMKNA 261 I M A Sbjct: 228 IDKIMKARA 236 >2ASU-B nrPDB Length = 234 Score = 87.0 bits (214), Expect = 7e-18, Method: Compositional matrix adjust. Identities = 73/250 (29%), Positives = 105/250 (42%), Gaps = 42/250 (16%) Query: 25 VVGGFNCKKNSQPWQVAVY-YQKEHICGGVLLDRNWVLTAAHCY------VDQYEVWLGK 77 VVGG + PW V++ Q +H CGG L+ W+LTA C+ + YEVWLG Sbjct: 1 VVGG---HPGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLG- 56 Query: 78 NKLFQE----EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADIT 133 LFQ EPS Q V+K P + L+LL+L + + Sbjct: 57 -TLFQNPQHGEPSLQRVPVAKMVCGPS-----------------GSQLVLLKLERSVTLN 98 Query: 134 DVVKPIALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK 191 V I LP + PG+KC +GWG T L + ++ N+ C + + Sbjct: 99 QRVALICLPPEWYVVPPGTKCEIAGWGETKGT--GNDTVLNVALLNVISNQECNIKHRGR 156 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLI 247 V + +C + C D GGPL C +L+G V C + PA++T + Sbjct: 157 VRESEMCTEGLLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRV-CARSRWPAVFTRVS 215 Query: 248 KFNSWIKDTM 257 F WI M Sbjct: 216 VFVDWIHKVM 225 >2OLG-A nrPDB Length = 278 Score = 87.0 bits (214), Expect = 8e-18, Method: Compositional matrix adjust. Identities = 66/246 (26%), Positives = 113/246 (45%), Gaps = 29/246 (11%) Query: 37 PWQVAVYYQ-----KEHICGGVLLDRNWVLTAAHCYVDQY--------EVWLGK-NKLFQ 82 PW + Y+ ++ CGG L++ +++TAAHC + +V LG+ N Sbjct: 35 PWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGALNKVRLGEWNTATD 94 Query: 83 EEPSAQHRLVSKSFP-HPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + R+ P G ++ + D +D+ L+RL++ + T+ ++P+ L Sbjct: 95 PDCYGAVRVCVPDKPIDLGIEETIQHPDYVDGSKDRYHDIALIRLNRQVEFTNYIRPVCL 154 Query: 142 --PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ---KVTDVM 196 P +E + G + GWG ++ Q + + ++ E CAK + +V Sbjct: 155 PQPNEEVQVGQRLTVVGWGRTETGQYSTIK--QKLAVPVVHAEQCAKTFGAAGVRVRSSQ 212 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSYGPVPCGKPGVPAIYTNLIKFNS 251 LCAG KD+C DSGGPL+ + L+G S+G CG G P IYT + K+ Sbjct: 213 LCAGGE-KAKDSCGGDSGGPLLAERANQQFFLEGLVSFGAT-CGTEGWPGIYTKVGKYRD 270 Query: 252 WIKDTM 257 WI+ + Sbjct: 271 WIEGNI 276 >5UBM-A nrPDB Length = 252 Score = 85.9 bits (211), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 80/266 (30%), Positives = 118/266 (44%), Gaps = 47/266 (17%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--VWLGKNKLF 81 R++GG + + PWQV + GG L++ WVLTAAH E +++G + Sbjct: 1 RIIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSV- 56 Query: 82 QEEPSAQHRLVSKS--FPHPGFNMSLLMLQTIPPG-ADFSNDLMLLRLSKPADITDVVKP 138 Q A+ ++++ F HPG+ L +P G +F ND+ L+RL P + V P Sbjct: 57 QTSRLAKSKMLTPEHVFIHPGWK-----LLEVPEGRTNFDNDIALVRLKDPVKMGPTVSP 111 Query: 139 IALPTKEPK----PGSKCLASGWGSITPTRWQKPD---DLQCVFITLLPNENCAKVYLQK 191 I LP G L SGWG R +K D L+ + + P C +V ++K Sbjct: 112 ICLPGTSSDYNLMDGDLGLISGWG-----RTEKRDRAVRLKAARLPVAPLRKCKEVKVEK 166 Query: 192 ---------VTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTSYGPVPCG 235 T M+CAG G D+C+ DSGG G S+GP CG Sbjct: 167 PTADAEAYVFTPNMICAGGE-KGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-QCG 224 Query: 236 KPGVPAIYTNLIKFNSWIKDTMMKNA 261 G +YT + + WI TM +N+ Sbjct: 225 TYG---LYTRVKNYVDWIMKTMQENS 247 >1C5M-D nrPDB Length = 255 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 70/248 (28%), Positives = 104/248 (41%), Gaps = 31/248 (12%) Query: 25 VVGGFNCKKNSQPWQ-VAVYYQKEHICGGVLLDRNWVLTAAHCY--VDQYEVWLGKNKLF 81 +VGG CK PWQ + + + E CGG +L ++LTAAHC +++V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 QEE V H F DF D+ +LRL P V P L Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKETY---------DF--DIAVLRLKTPITFRMNVAPACL 109 Query: 142 PTKE--------PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT 193 P ++ K G + SG+G T + ++ L+ + + + +C +T Sbjct: 110 PERDWAESTLMTQKTG---IVSGFGR-THEKGRQSTRLKMLEVPYVDRNSCKLSSSFIIT 165 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 M CAG +D C+ DSGGP + + G S+G C + G IYT + F Sbjct: 166 QNMFCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKYGIYTKVTAF 224 Query: 250 NSWIKDTM 257 WI +M Sbjct: 225 LKWIDRSM 232 >1ELV-A nrPDB Length = 333 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 80/268 (29%), Positives = 119/268 (44%), Gaps = 47/268 (17%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--VWLGKNK 79 + R++GG + + PWQV + GG L++ WVLTAAH E +++G Sbjct: 80 KQRIIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTS 136 Query: 80 LFQEEPSAQHRLVSKS--FPHPGFNMSLLMLQTIPPG-ADFSNDLMLLRLSKPADITDVV 136 + Q A+ ++++ F HPG+ L +P G +F ND+ L+RL P + V Sbjct: 137 V-QTSRLAKSKMLTPEHVFIHPGWK-----LLAVPEGRTNFDNDIALVRLKDPVKMGPTV 190 Query: 137 KPIALPTKEPK----PGSKCLASGWGSITPTRWQKPD---DLQCVFITLLPNENCAKVYL 189 PI LP G L SGWG R +K D L+ + + P C +V + Sbjct: 191 SPICLPGTSSDYNLMDGDLGLISGWG-----RTEKRDRAVRLKAARLPVAPLRKCKEVKV 245 Query: 190 QK---------VTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTSYGPVP 233 +K T M+CAG G D+C+ DSGG G S+GP Sbjct: 246 EKPTADAEAYVFTPNMICAGGE-KGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-Q 303 Query: 234 CGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 CG G +YT + + WI TM +N+ Sbjct: 304 CGTYG---LYTRVKNYVDWIMKTMQENS 328 >4J1Y-A nrPDB Length = 397 Score = 84.0 bits (206), Expect = 5e-17, Method: Compositional matrix adjust. Identities = 80/268 (29%), Positives = 119/268 (44%), Gaps = 47/268 (17%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--VWLGKNK 79 ++R +GG + + PWQV + GG L++ WVLTAAH E +++G Sbjct: 144 KARAIGGSDADIKNFPWQV---FFDNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTS 200 Query: 80 LFQEEPSAQHRLVSKS--FPHPGFNMSLLMLQTIPPG-ADFSNDLMLLRLSKPADITDVV 136 + Q A+ ++++ F HPG+ L +P G +F ND+ L+RL P + V Sbjct: 201 V-QTSRLAKSKMLTPEHVFIHPGWK-----LLEVPEGRTNFDNDIALVRLKDPVKMGPTV 254 Query: 137 KPIALPTKEPK----PGSKCLASGWGSITPTRWQKPD---DLQCVFITLLPNENCAKVYL 189 PI LP G L SGWG R +K D L+ + + P C +V + Sbjct: 255 SPICLPGTSSDYNLMDGDLGLISGWG-----RTEKRDRAVRLKAARLPVAPLRKCKEVKV 309 Query: 190 QK---------VTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTSYGPVP 233 +K T M+CAG G D+C+ DSGG G S+GP Sbjct: 310 EKPTADAEAYVFTPNMICAGGE-KGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGP-Q 367 Query: 234 CGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 CG G +YT + + WI TM +N+ Sbjct: 368 CGTYG---LYTRVKNYVDWIMKTMQENS 392 >1YM0-A nrPDB Length = 238 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 73/247 (29%), Positives = 111/247 (44%), Gaps = 20/247 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE--HICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 +VGG + PWQV+V + H CGG +++ WV+ AAHC Q E + + Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCM--QGEAPALVSLVVG 58 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 E S+ V ++ S+ + + P A ND+ +++ + V PI P Sbjct: 59 EHDSSAASTVRQTHDVD----SIFVNENYDP-ATLENDVSVIKTAVAITFDINVGPICAP 113 Query: 143 T-KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTDVMLCAG 200 K SGWG+I P L+ V + + N C VY + D M+CA Sbjct: 114 DPANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDMICAT 173 Query: 201 EMGG--GKDTCRDDSGGPL-ICDG----ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 + G +D+C+ DSGGPL + DG L G S+G + C G P +Y+ + WI Sbjct: 174 DNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWG-IGCAS-GYPGVYSRVGFHAGWI 231 Query: 254 KDTMMKN 260 DT+ N Sbjct: 232 TDTITNN 238 >1PPF-E nrPDB Length = 218 Score = 84.0 bits (206), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 66/239 (27%), Positives = 114/239 (47%), Gaps = 28/239 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC----YVDQYEVWLGKNKL 80 +VGG + ++ P+ V++ + H CG L+ N+V++AAHC V V LG + L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + EP+ Q V + F + ++LL ND+++L+L+ A I V+ Sbjct: 61 SRREPTRQVFAVQRIFENGYDPVNLL------------NDIVILQLNGSATINANVQVAQ 108 Query: 141 LPTKEPKPGS--KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 LP + + G+ +CLA GWG + R LQ + +T++ + L + ++V C Sbjct: 109 LPAQGRRLGNGVQCLAMGWGLLGRNRG-IASVLQELNVTVVTS-------LCRRSNV--C 158 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G C DSG PL+C+G++ G S+ C P + + +F +WI + Sbjct: 159 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSII 217 >2B9L-A nrPDB Length = 394 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 77/278 (27%), Positives = 121/278 (43%), Gaps = 48/278 (17%) Query: 14 GIDAAPPLQSRVVGGFNCKKNSQ-PWQVAVYY--------QKEHICGGVLLDRNWVLTAA 64 GI L ++ G N + + PW VAV +++ +CGG L+ + VLT A Sbjct: 119 GIRNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGA 178 Query: 65 HCYVDQYEVWLGKNKLF---------QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGA 115 HC V+ Y+ L K+ +E Q R + + H FN ++ Sbjct: 179 HC-VNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVV-------- 229 Query: 116 DFSNDLMLLRLSKPADITDVVKPIALPTK-EPKPGSKCLASGWGSIT-PTRWQKPDDLQC 173 ND+ LL L +P D + I LP + + ++C ASGWG +R + + L+ Sbjct: 230 ---NDVALLLLDRPLVQADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKK 286 Query: 174 VFITLLPNENC------AKVYLQKVTD-VMLCAGEMGGGKDTCRDDSGGPLICDG----- 221 + + + + C ++ L+ V D +CAG G KDTC D G PL C Sbjct: 287 IQLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGGEQG-KDTCTGDGGSPLFCPDPRNPS 345 Query: 222 --ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 + G ++G + CG VP +Y N+ F +WI M Sbjct: 346 RYMQMGIVAWG-IGCGDENVPGVYANVAHFRNWIDQEM 382 >1AKS-B nrPDB Length = 98 Score = 80.1 bits (196), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 37/93 (39%), Positives = 57/93 (61%), Gaps = 1/93 (1%) Query: 168 PDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTT 227 P LQC+ +L N +C Y ++T M+C G + GGKD+C+ DSGGP++C+G LQG Sbjct: 7 PSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNGQLQGIV 66 Query: 228 SYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 S+G C + P +YT + + +WI+ T+ N Sbjct: 67 SWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >4BXW-A nrPDB Length = 423 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 72/254 (28%), Positives = 106/254 (41%), Gaps = 29/254 (11%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHI-CGGVLLDRNWVLTAAHCY--VDQYEVWLGKNKL 80 R+V G +CK PWQ A+ +KE + CGG +L +VLTAAHC + V +G+ Sbjct: 169 RIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINETETISVVVGEIDK 228 Query: 81 FQEEP----SAQHRLVSKSF--PHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITD 134 + E S V K F P + L A + D+ ++++ P ++ Sbjct: 229 SRIETGPLLSVDKIYVHKKFVPPQKAYKFDL---------AAYDYDIAIIQMKTPIQFSE 279 Query: 135 VVKPIALPTKEPK-----PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL 189 V P LPT + + SG+G I + K L+ + + + C Sbjct: 280 NVVPACLPTADFANQVLMKQDFGIVSGFGRIVE-KGPKSKTLKVLKVPYVDRHTCMVSSE 338 Query: 190 QKVTDVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTN 245 +T M CAG +D C+ DSGGP + G S G C + G YT Sbjct: 339 TPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGE-GCARNGKYGNYTK 397 Query: 246 LIKFNSWIKDTMMK 259 L KF WIK M + Sbjct: 398 LSKFIPWIKRIMRQ 411 >3H7O-A nrPDB Length = 228 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 111/244 (45%), Gaps = 27/244 (11%) Query: 27 GGFNCKKNSQPWQVAV--YYQKEHI-CGGVLLDRNWVLTAAHCYVDQYE---VWLGKNKL 80 GG PW VAV Y +E + CGG +L + +VLTAAHC DQ V ++ Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV-VKPI 139 E+P VS + +S +T+ ND+ +L LS+P + + KP Sbjct: 62 LWEDPGKSDPYVSHVY------LSFYRQETM------ENDIAILELSRPLKLDGLKSKPA 109 Query: 140 ALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV-M 196 LP E PK GS L SG+G T K DL+ +T++ + C Y + + Sbjct: 110 KLPDIEFRPKTGSDVLVSGYGD-GQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQV 168 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 CA ++G ++ D+G P + L G +Y P G P ++T + + SWI+D Sbjct: 169 FCAQKVGVSLESG--DAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDI 224 Query: 257 MMKN 260 + K Sbjct: 225 IKKK 228 >2HLC-A nrPDB Length = 230 Score = 74.3 bits (181), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 103/246 (41%), Gaps = 39/246 (15%) Query: 25 VVGGFNCKKNSQPWQ----VAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--VWLGKN 78 ++ G+ P+Q + + Q+ CGG L+D W+LTAAHC D V+LG Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 79 KLFQEEPSAQ-HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 ++ E R++S S +P + ND+ L+++ + TD ++ Sbjct: 61 VQYEGEAVVNSERIISHSMFNPD---------------TYLNDVALIKIPH-VEYTDNIQ 104 Query: 138 PIALPTKEPKPGSK----CLASGWGSITPTRWQKPDD---LQCVFITLLPNENCAKVYLQ 190 PI LP+ E SGWG Q D LQ + ++ N+ CA+ Y Sbjct: 105 PIRLPSGEELNNKFENIWATVSGWG-------QSNTDTVILQYTYNLVIDNDRCAQEYPP 157 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLICD--GILQGTTSYGPVPCGKPGVPAIYTNLIK 248 + G+ GK C DSGGP + +L G S+ + G P ++ + Sbjct: 158 GIIVESTICGDTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTS 217 Query: 249 FNSWIK 254 + WI+ Sbjct: 218 YMDWIQ 223 >6BQM-A nrPDB Length = 506 Score = 73.6 bits (179), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 75/261 (28%), Positives = 111/261 (42%), Gaps = 39/261 (14%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQKE-HI-CGGVLLDRNWVLTAAHCYVDQYE-----V 73 + SR++GG P+ VA+ + H+ CGG L +VLTAAHC VD+ + V Sbjct: 7 VSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHC-VDKEDPAKGDV 65 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK-PADI 132 LG + + +A+ V + + H + A ND+ +L L + P Sbjct: 66 LLGAFDM-NDVNTAERIHVRQIYVHNSYIT-----------ASMGNDIAVLELERDPLPR 113 Query: 133 TDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDD---LQCVFITLLPNENC----- 184 V + E S G+G+ +K D L V + +P C Sbjct: 114 RSVQISDSSDFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGS 173 Query: 185 ---AKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD---GILQ-GTTSYGPVPCGKP 237 AK ++T+ CAG G KD C D+GGP+ D G Q G S+G CG+ Sbjct: 174 DQDAKNNYSQLTNNAFCAGSFG--KDACSGDAGGPIFFDSNNGRKQMGVVSWGD-GCGRA 230 Query: 238 GVPAIYTNLIKFNSWIKDTMM 258 P +YTNL FN W+ D + Sbjct: 231 NSPGVYTNLSVFNDWLDDQQL 251 >2JET-B nrPDB Length = 128 Score = 73.6 bits (179), Expect = 9e-14, Method: Compositional matrix adjust. Identities = 43/128 (33%), Positives = 68/128 (53%), Gaps = 15/128 (11%) Query: 35 SQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWL-GKNKLFQEEPSAQHRLV 92 S PWQV++ + H CGG L+ +WV+TAAHC V +V + G+ +E + Q + Sbjct: 8 SWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEENIQVLKI 67 Query: 93 SKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK--PGS 150 ++ F +P FNM + ND+ LL+L+ PA ++ V + LP + PG+ Sbjct: 68 AQVFKNPKFNMFTV-----------RNDITLLKLATPAQFSETVSAVCLPNVDDDFPPGT 116 Query: 151 KCLASGWG 158 C +GWG Sbjct: 117 VCATTGWG 124 >3H7T-A nrPDB Length = 235 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 57/218 (26%), Positives = 90/218 (41%), Gaps = 29/218 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD-----QYEVWLGKNK 79 ++GG +PW V V ++ CGG +L N+V+TAA C VD + G + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQC-VDGTKPSDISIHYGSSY 59 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITD-VVKP 138 + S + + HP L +Q N+ ++ P + D K Sbjct: 60 RTTKGTSVMAKKIYIVRYHP------LTMQ---------NNYAVIETEMPIKLDDKTTKK 104 Query: 139 IALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-----K 191 I LP+ +P+P + L SGWGS + DL T++ ++C + Y Q Sbjct: 105 IELPSLLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKY 164 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSY 229 + D + CAG D+G P + +G L G SY Sbjct: 165 IYDGVFCAGGEYDETYIGYGDAGDPAVQNGTLVGVASY 202 >3VGC-B nrPDB Length = 131 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 44/138 (31%), Positives = 68/138 (49%), Gaps = 15/138 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWL-GKNKLFQ 82 +V G S PWQV++ + H CGG L++ NWV+TAAHC V +V + G+ Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 Q ++K F + +N SL + +ND+ LL+LS A + V + LP Sbjct: 61 SSEKIQKLKIAKVFKNSKYN-SLTI----------NNDITLLKLSTAASFSQTVSAVCLP 109 Query: 143 TKEP--KPGSKCLASGWG 158 + G+ C+ +GWG Sbjct: 110 SASDDFAAGTTCVTTGWG 127 >4LK4-A nrPDB Length = 357 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 69/259 (26%), Positives = 114/259 (44%), Gaps = 38/259 (14%) Query: 15 IDAAPPLQSRVVGGFNCKKNSQPWQVAVY------YQKEHICGGVLLDRNWVLTAAHCY- 67 +++ + SR++ G N P VA+ YQ + CGG L +VLTAAHC+ Sbjct: 1 MESTADISSRIINGSNANSAEWPSIVALVKRGADAYQGQ-FCGGSFLGGRYVLTAAHCFD 59 Query: 68 ---VDQYEVWLGKNKLFQEEPSAQHRLVS-KSFPHPGFNMSLLMLQTIPPGADFSNDLML 123 +V +G L S R+ + K + H ++ S L+ ND+ + Sbjct: 60 SRSAASVDVIIGAYDL--NNSSQGERIAAQKIYRHLSYSPSNLL-----------NDIAI 106 Query: 124 LRLSKPADITDVVKPIALP-TKEPKPG-SKCLASGWGSITPTRW-QKPDDLQCVFITLLP 180 + L++ + + + +A P T+ P + +GWG ++ Q LQ V + L+ Sbjct: 107 VELAQTSSLPAIT--LAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVS 164 Query: 181 NENCAKVYLQKVTD----VMLCAGEMGGGKDTCRDDSGGPLICD-GILQ-GTTSYGPVPC 234 C V ++ CA + KD+C+ D+GGP++ G Q G S+G C Sbjct: 165 QSLCQIVMQHGISSDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQC 222 Query: 235 GKPGVPAIYTNLIKFNSWI 253 K G +YTN+ F WI Sbjct: 223 AKTGTYGVYTNVSYFRDWI 241 >1BBR-H nrPDB Length = 150 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 44/157 (28%), Positives = 73/157 (46%), Gaps = 28/157 (17%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC VD Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + ++ K + HP +N + D+ LL+L +P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT 163 ++D + P+ LP K+ G K +GWG+ T Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >1RIW-B nrPDB Length = 147 Score = 66.2 bits (160), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 74/157 (47%), Gaps = 28/157 (17%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV----------DQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC + + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + + ++ K + HP +N + D+ L++L KP Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT 163 +D + P+ LP +E + G K +GWG++ T Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET 147 >1M9U-A nrPDB Length = 241 Score = 64.7 bits (156), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 67/252 (26%), Positives = 100/252 (39%), Gaps = 34/252 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYV----DQYEVWLGK 77 V+GG N PWQ++ Q H CG LL L+A+HC + V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAG- 59 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPG-ADFSNDLMLLRLSKPADITDVV 136 L+Q+ ++ + + S M + G A +SND+ +L L+ + + Sbjct: 60 --LWQQSDTSGTQTANVD--------SYTMHENYGAGTASYSNDIAILHLATSISLGGNI 109 Query: 137 KPIALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL----Q 190 + LP G+ C+ SGWG T PD LQ I ++ C + Sbjct: 110 QAAVLPANNNNDYAGTTCVISGWGRTDGTN-NLPDILQKSSIPVITTAQCTAAMVGVGGA 168 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLICD-------GILQGTTSYGPVPCGKPGVPAIY 243 + D +C + G C DSGGPL C G+ S G C P P++Y Sbjct: 169 NIWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGAC-LPDYPSVY 227 Query: 244 TNLIKFNSWIKD 255 T + + WI D Sbjct: 228 TRVSAYLGWIGD 239 >3RU4-E nrPDB Length = 96 Score = 64.3 bits (155), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 35/97 (36%), Positives = 48/97 (49%), Gaps = 7/97 (7%) Query: 168 PDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG----IL 223 PD LQ + LL N NC K + K+ D M+CAG G +C DSGGPL+C L Sbjct: 3 PDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGA--SGVSSCMGDSGGPLVCKKNGAWTL 60 Query: 224 QGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 G S+G C P +Y + +W++ T+ N Sbjct: 61 VGIVSWGSSTC-STSTPGVYARVTALVNWVQQTLAAN 96 >3I77-A nrPDB Length = 230 Score = 64.3 bits (155), Expect = 6e-11, Method: Compositional matrix adjust. Identities = 70/241 (29%), Positives = 105/241 (43%), Gaps = 30/241 (12%) Query: 25 VVGGFNCKKNSQPWQVA-VYYQKEHICGGVLLDRNWVLTAAHCYV---DQYEVWLGKNKL 80 VVGG + P+ V + + E CGG L ++ VLTAAHC + + + Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + SA +K PGF + D L++L++P I IA Sbjct: 61 DLQSSSAVKVRSTKVLQAPGFTKET-----------YGKDWALIKLAQP--INQPTLKIA 107 Query: 141 LPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCV--FITLLPNENCAKVYLQKVTDVMLC 198 T + G+ +A GWG+ Q+ L+ F++ + + L V + M+C Sbjct: 108 TTTAYNQ-GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSSSSFIL--VANEMIC 163 Query: 199 AGE-MGGGKDTCRDDSGGPLI----CDGILQ-GTTSYGPVPCGKPGVPAIYTNLIKFNSW 252 AG GG DTC+ DSGGP+ D +Q G S+G C +PG P +YT + F S Sbjct: 164 AGYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFASA 222 Query: 253 I 253 I Sbjct: 223 I 223 >2JET-C nrPDB Length = 99 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 34/99 (34%), Positives = 52/99 (52%), Gaps = 7/99 (7%) Query: 166 QKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC--DGI- 222 + P+ LQ + ++ +C K + K+TDVM CAG G D+C DSGGPL+C DG+ Sbjct: 4 KTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAG--ASGVDSCMGDSGGPLVCQKDGVW 61 Query: 223 -LQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 L G S+G C P +Y+ + W++ + N Sbjct: 62 TLAGIVSWGSGVC-STSTPGVYSRVTALMPWVQQILEAN 99 >4X0L-C nrPDB Length = 259 Score = 60.5 bits (145), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 59/266 (22%), Positives = 107/266 (40%), Gaps = 38/266 (14%) Query: 18 APPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGK 77 A P+Q R++GG K S PWQ + G L++ W+LT A K Sbjct: 9 ANPVQ-RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA------------K 55 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSN-DLMLLRLSKPADITDVV 136 N +A + ++ + L+ ++ + ++S D+ L++L + + + V Sbjct: 56 NLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERV 115 Query: 137 KPIALPTKE-PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-----Q 190 PI LP+K+ + G SGWG ++ D L+ V + + + C + Y + Sbjct: 116 MPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPE 173 Query: 191 KVT------------DVMLCAGEMGGGKDTCRDDSGGPLICDGILQGT-TSYGPVPCGKP 237 K T + CAG +DTC D+G + + T + G + K Sbjct: 174 KKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS 233 Query: 238 GVPA---IYTNLIKFNSWIKDTMMKN 260 A +Y + W++ T+ +N Sbjct: 234 CAVAEYGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 59/266 (22%), Positives = 107/266 (40%), Gaps = 38/266 (14%) Query: 18 APPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGK 77 A P+Q R++GG K S PWQ + G L++ W+LT A K Sbjct: 65 ANPVQ-RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTA------------K 111 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSN-DLMLLRLSKPADITDVV 136 N +A + ++ + L+ ++ + ++S D+ L++L + + + V Sbjct: 112 NLFLNHSENATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQVDIGLIKLKQKVSVNERV 171 Query: 137 KPIALPTKE-PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-----Q 190 PI LP+K+ + G SGWG ++ D L+ V + + + C + Y + Sbjct: 172 MPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYEGSTVPE 229 Query: 191 KVT------------DVMLCAGEMGGGKDTCRDDSGGPLICDGILQGT-TSYGPVPCGKP 237 K T + CAG +DTC D+G + + T + G + K Sbjct: 230 KKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGILSFDKS 289 Query: 238 GVPA---IYTNLIKFNSWIKDTMMKN 260 A +Y + W++ T+ +N Sbjct: 290 CAVAEYGVYVKVTSIQDWVQKTIAEN 315 >1MD7-A nrPDB Length = 328 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 65/258 (25%), Positives = 101/258 (39%), Gaps = 39/258 (15%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC-YVDQYE-------- 72 + R++GG K + PWQV GG LL W+LTAAH Y ++E Sbjct: 87 RQRIIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 73 VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADI 132 V+LG + + H + S HP + +F D+ LL L + Sbjct: 145 VFLGHTNVEELMKLGNHPIRRVSV-HPDYRQD--------ESYNFEGDIALLELENSVTL 195 Query: 133 TDVVKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC-----A 185 + PI LP + G SG+G + + DL+ V + + + C Sbjct: 196 GPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRG 252 Query: 186 KVYLQKVTDVMLCAGEMGGGKDTCRDDSGG------PLICDGILQGTTSYGPVPCGKPGV 239 K + + M CAG +D C+ D+GG P + G S+G + C + Sbjct: 253 KNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWG-IGCSRG-- 309 Query: 240 PAIYTNLIKFNSWIKDTM 257 YT ++ + WIK M Sbjct: 310 YGFYTKVLNYVDWIKKEM 327 >2QY0-B nrPDB Length = 242 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 65/255 (25%), Positives = 99/255 (38%), Gaps = 39/255 (15%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC-YVDQYE--------VWL 75 ++GG K + PWQV GG LL W+LTAAH Y ++E V+L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGR--GGGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 76 GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV 135 G + + H + S HP + +F D+ LL L + Sbjct: 59 GHTNVEELMKLGNHPIRRVSV-HPDYRQD--------ESYNFEGDIALLELENSVTLGPN 109 Query: 136 VKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC-----AKVY 188 + PI LP + G SG+G + + DL+ V + + + C K Sbjct: 110 LLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRGKNR 166 Query: 189 LQKVTDVMLCAGEMGGGKDTCRDDSGG------PLICDGILQGTTSYGPVPCGKPGVPAI 242 + + M CAG +D C+ DSGG P + G S+G + C + Sbjct: 167 MDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG-IGCSRG--YGF 223 Query: 243 YTNLIKFNSWIKDTM 257 YT ++ + WIK M Sbjct: 224 YTKVLNYVDWIKKEM 238 >1GPZ-A nrPDB Length = 399 Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 67/262 (25%), Positives = 103/262 (39%), Gaps = 41/262 (15%) Query: 20 PLQSR--VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC-YVDQYE---- 72 P++ R ++GG K + PWQV GG LL W+LTAAH Y ++E Sbjct: 151 PVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSN 208 Query: 73 ----VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 V+LG + + H + S HP + +F D+ LL L Sbjct: 209 ASLDVFLGHTNVEELMKLGNHPIRRVSV-HPDYRQD--------ESYNFEGDIALLELEN 259 Query: 129 PADITDVVKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC-- 184 + + PI LP + G SG+G + + DL+ V + + + C Sbjct: 260 SVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACEN 316 Query: 185 ---AKVYLQKVTDVMLCAGEMGGGKDTCRDDSGG------PLICDGILQGTTSYGPVPCG 235 K + + M CAG +D C+ DSGG P + G S+G + C Sbjct: 317 WLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG-IGCS 375 Query: 236 KPGVPAIYTNLIKFNSWIKDTM 257 + YT ++ + WIK M Sbjct: 376 RG--YGFYTKVLNYVDWIKKEM 395 >2FMJ-A nrPDB Length = 222 Score = 57.0 bits (136), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 66/238 (27%), Positives = 101/238 (42%), Gaps = 32/238 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV---DQYEVWLGKNKLF 81 VVGG + P+ V + CGG L ++ VLTAAHC + + + Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + SA +K PG+N + D L++L++P I IA Sbjct: 57 LQSSSAVKVRSTKVLQAPGYNGT-------------GKDWALIKLAQP--INQPTLKIAT 101 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTDVMLCAG 200 T + G+ +A GWG+ Q+ L+ + + + C Y + V + +CAG Sbjct: 102 TTAYNQ-GTFTVA-GWGANREGGSQQRYLLK-ANVPFVSDAACRSAYGNELVANEEICAG 158 Query: 201 EMGGGKDTCRDDSGGPLI----CDGILQ-GTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 GG DTC+ DSGGP+ D +Q G S+G C + G +YT + F S I Sbjct: 159 YDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGE-GCARKGKYGVYTEVSTFASAI 215 >2I6S-A nrPDB Length = 517 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 36/125 (28%), Positives = 62/125 (49%), Gaps = 14/125 (11%) Query: 26 VGGFNCKKNSQ---PWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKNKL 80 VG + + Q PW V + + + C G L+ WVLTAAHC+ D + +W ++ Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLW----RV 285 Query: 81 FQEEPSAQ---HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 +P +Q L+ K+ PGF++ Q I + +D+ LL+L++ ++ + Sbjct: 286 NVGDPKSQWGKEFLIEKAVISPGFDVFAKKNQGILEF--YGDDIALLKLAQKVKMSTHAR 343 Query: 138 PIALP 142 PI LP Sbjct: 344 PICLP 348 >1EPT-B nrPDB Length = 82 Score = 52.8 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 29/88 (32%), Positives = 44/88 (50%), Gaps = 11/88 (12%) Query: 72 EVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 +V LG++ + E + Q +K HP FN G ND+ML++LS PA Sbjct: 4 QVRLGEHNIDVLEGNEQFINAAKIITHPNFN-----------GNTLDNDIMLIKLSSPAT 52 Query: 132 ITDVVKPIALPTKEPKPGSKCLASGWGS 159 + V ++LP G++CL SGWG+ Sbjct: 53 LNSRVATVSLPRSCAAAGTECLISGWGN 80 >3BEU-A nrPDB Length = 224 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 65/239 (27%), Positives = 100/239 (41%), Gaps = 32/239 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV---DQYEVWLGKNKLF 81 VVGG + P+ V + CGG L ++ VLTAAHC + + + Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + SA +K PGF + D L++L++P I IA Sbjct: 57 LQSSSAVKVRSTKVLQAPGFTKET-----------YGKDWALIKLAQP--INQPTLKIAT 103 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCV--FITLLPNENCAKVYLQKVTDVMLCA 199 T + G+ +A GWG+ Q+ L+ F++ + + L V + M+CA Sbjct: 104 TTAYNQ-GTFTVA-GWGANREGGSQQRYLLKANVPFVSDAACRSSSSFIL--VANEMICA 159 Query: 200 GEMGGGKDTCRDDSGGPLI----CDGILQ-GTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 G +DTC+ DSGGP+ D +Q G S+G C + G +YT + F S I Sbjct: 160 GYDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGE-GCARKGKYGVYTEVSTFASAI 217 >1DLE-A nrPDB Length = 298 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 72/277 (25%), Positives = 111/277 (40%), Gaps = 62/277 (22%) Query: 34 NSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCY-VDQYEVWLGKNKLFQEEPSAQ 88 + QPWQ + + C G ++ +VLTAAHC+ VD E + K + E+ + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSI-KVSVGGEKRDLE 83 Query: 89 HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKP 148 +V HP +N++ IP D+ D+ L++L ++PI LP E Sbjct: 84 IEVV---LFHPNYNINGKKEAGIPEFYDY--DVALIKLKNKLKYGQTIRPICLPCTE--- 135 Query: 149 GSKCLASGWGSITPTRWQKPD-----DLQCVFITLLPNENCAK-VYLQ------------ 190 A T + QK + D++ +F++ + K VY++ Sbjct: 136 -GTTRALRLPPTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 194 Query: 191 -------KVTDV-------MLCAGEMGGGKD--TCRDDSGGPLICDG----ILQGTTSYG 230 KV D+ LC G + D TCR DSGGPLI I G S+G Sbjct: 195 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 Query: 231 PVPCGK-----PGVPA----IYTNLIKFNSWIKDTMM 258 V K VPA + NL + W+K+ + Sbjct: 255 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 291 >2WIN-I nrPDB Length = 507 Score = 51.2 bits (121), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 72/276 (26%), Positives = 112/276 (40%), Gaps = 62/276 (22%) Query: 34 NSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCY-VDQYEVWLGKNKLFQEEPSAQ 88 + QPWQ + + C G ++ +VLTAAHC+ VD E + K + E+ + Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSI-KVSVGGEKRDLE 290 Query: 89 HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKP 148 +V HP +N++ IP D+ D+ L++L ++PI LP E Sbjct: 291 IEVV---LFHPNYNINGKKEAGIPEFYDY--DVALIKLKNKLKYGQTIRPICLPCTEGTT 345 Query: 149 GSKCLASGWGSITPTRWQKPD-----DLQCVFITLLPNENCAK-VYLQ------------ 190 + L T + QK + D++ +F++ + K VY++ Sbjct: 346 RALRLP----PTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 401 Query: 191 -------KVTDV-------MLCAGEMGGGKD--TCRDDSGGPLICDG----ILQGTTSYG 230 KV D+ LC G + D TCR DSGGPLI I G S+G Sbjct: 402 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 Query: 231 PVPCGK-----PGVPA----IYTNLIKFNSWIKDTM 257 V K VPA + NL + W+K+ + Sbjct: 462 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKL 497 >2OK5-A nrPDB Length = 752 Score = 50.8 bits (120), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 72/277 (25%), Positives = 112/277 (40%), Gaps = 62/277 (22%) Query: 34 NSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCY-VDQYEVWLGKNKLFQEEPSAQ 88 + QPWQ + + C G ++ +VLTAAHC+ VD E + K + E+ + Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDKEHSI-KVSVGGEKRDLE 534 Query: 89 HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKP 148 +V HP +N++ IP D+ D+ L++L ++PI LP E Sbjct: 535 IEVV---LFHPNYNINGKKEAGIPEFYDY--DVALIKLKNKLKYGQTIRPICLPCTEGTT 589 Query: 149 GSKCLASGWGSITPTRWQKPD-----DLQCVFITLLPNENCAK-VYLQ------------ 190 + L T + QK + D++ +F++ + K VY++ Sbjct: 590 RALRLP----PTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 645 Query: 191 -------KVTDV-------MLCAGEMGGGKD--TCRDDSGGPLICDG----ILQGTTSYG 230 KV D+ LC G + D TCR DSGGPLI I G S+G Sbjct: 646 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 Query: 231 PVPCGK-----PGVPA----IYTNLIKFNSWIKDTMM 258 V K VPA + NL + W+K+ + Sbjct: 706 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQ 742 >4F4O-C nrPDB Length = 347 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 61/266 (22%), Positives = 99/266 (37%), Gaps = 49/266 (18%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLG-KNKLFQ 82 R++GG K S PWQ + G L++ W+LT A + LG KN Sbjct: 102 RIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTAK------NLRLGHKNDTKA 155 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 ++ + RL + G + + + I + + D+ L++L + + + V PI LP Sbjct: 156 KDIAPTLRL------YVGKKQEVEIEKVIFHPDNSTVDIGLIKLKQKVPVNERVMPICLP 209 Query: 143 TKE-PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-----QKVT--- 193 +K+ G SGWG + + L+ V + + E C + Y +K T Sbjct: 210 SKDYVNVGLVGYVSGWGRNANLNFT--EHLKYVMLPVADQEKCVQYYEGSTVPEKKTPKS 267 Query: 194 ---------DVMLCAGEMGGGKDTCRDDSGGPLICD----------GILQGTTSYGPVPC 234 + CAG +DTC D+G GIL S Sbjct: 268 PVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKDDDTWYAAGILSFDKSCRTAEY 327 Query: 235 GKPGVPAIYTNLIKFNSWIKDTMMKN 260 G +Y + WI+ T+ N Sbjct: 328 G------VYVRVTSILDWIQTTIADN 347 >1BBR-E nrPDB Length = 109 Score = 44.7 bits (104), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 31/100 (31%), Positives = 45/100 (45%), Gaps = 10/100 (10%) Query: 167 KPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAG-EMGGGK--DTCRDDSGGPLICDG-- 221 +P LQ V + L+ C ++TD M CAG + G GK D C DSGGP + Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 222 ----ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G S+G C + G YT++ + WI+ + Sbjct: 66 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 104 >2HNT-F nrPDB Length = 105 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 28/100 (28%), Positives = 43/100 (43%), Gaps = 10/100 (10%) Query: 167 KPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAG---EMGGGKDTCRDDSGGPLICDGIL 223 +P LQ V + ++ C ++TD M CAG + G D C DSGGP + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 224 Q------GTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G S+G C + G YT++ + WI+ + Sbjct: 62 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 100 >3F1S-B nrPDB Length = 283 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 56/233 (24%), Positives = 86/233 (36%), Gaps = 34/233 (14%) Query: 37 PWQVAVYYQK-EHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKS 95 PWQV + + + CGGV++ N+VLT A C + + + K + S ++ + Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKIT 121 Query: 96 FPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK-----PGS 150 H + M G NDL LL L P P+ P K+ P + Sbjct: 122 HVH------VHMRYDADAG---ENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT 172 Query: 151 KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC------AGEMGG 204 + L SGW + L +TL+ E C +V VT C A Sbjct: 173 RGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD 229 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G R+ G + G+L G P G + T + +++ W K M Sbjct: 230 GSVVTREHRGSWFL-TGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 275 >3H5C-B nrPDB Length = 317 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 56/233 (24%), Positives = 86/233 (36%), Gaps = 34/233 (14%) Query: 37 PWQVAVYYQK-EHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKS 95 PWQV + + + CGGV++ N+VLT A C + + + K + S ++ + Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV---KTYFNRTSQDPLMIKIT 162 Query: 96 FPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK-----PGS 150 H + M G NDL LL L P P+ P K+ P + Sbjct: 163 HVH------VHMRYDADAG---ENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT 213 Query: 151 KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC------AGEMGG 204 + L SGW + L +TL+ E C +V VT C A Sbjct: 214 RGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD 270 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G R+ G + G+L G P G + T + +++ W K M Sbjct: 271 GSVVTREHRGSWFL-TGVL------GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >2HNT-C nrPDB Length = 70 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 18/46 (39%), Positives = 28/46 (60%), Gaps = 2/46 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCYV 68 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLL 46 >2HNT-E nrPDB Length = 81 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 15/78 (19%) Query: 91 LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEP---- 146 ++ K + HP +N + D+ L++L KP +D + P+ LP +E Sbjct: 7 MLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVAFSDYIHPVCLPDRETAASL 56 Query: 147 -KPGSKCLASGWGSITPT 163 + G K +GWG++ T Sbjct: 57 LQAGYKGRVTGWGNLKET 74 >3RSZ-A nrPDB Length = 725 Score = 30.8 bits (68), Expect = 0.62, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 Y P C GVP+I TN+ F S+++D + N Sbjct: 533 YTPAECTVMGVPSITTNVSGFGSYMEDLIETN 564 >4XZY-A nrPDB Length = 720 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/97 (23%), Positives = 38/97 (39%), Gaps = 21/97 (21%) Query: 50 CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQ 109 G V+ DR VLT HC D + Q + +H + F ++ Sbjct: 70 TGEVVSDRGLVLTNHHCGYD----------MIQAHSTLEHNYLENGF------WAMREAD 113 Query: 110 TIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEP 146 +P + D+ ++ + K D+TD VK K+P Sbjct: 114 ELP-----NKDISVVFIDKIEDVTDYVKKELKAIKDP 145 >1GEG-A nrPDB Length = 256 Score = 27.7 bits (60), Expect = 5.8, Method: Compositional matrix adjust. Identities = 14/42 (33%), Positives = 21/42 (50%) Query: 115 ADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASG 156 A+F+ + L RLS+P D+ V +A P + G L G Sbjct: 210 AEFAKRITLGRLSEPEDVAACVSYLASPDSDYMTGQSLLIDG 251 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1AO5-A nrPDB 348 1e-96 1SGF-G nrPDB 347 3e-96 4NFE-A nrPDB 337 3e-93 1SPJ-A nrPDB 333 6e-92 1SGF-A nrPDB 328 1e-90 5FXL-A nrPDB 328 1e-90 3QUM-P nrPDB 323 4e-89 1F7Z-A nrPDB 322 1e-88 4AN7-A nrPDB 321 2e-88 5C67-A nrPDB 319 7e-88 4WWY-A nrPDB 319 8e-88 1TON-A nrPDB 315 1e-86 1A0J-A nrPDB 313 4e-86 1UTJ-A nrPDB 312 7e-86 5MS3-A nrPDB 304 4e-83 1NPM-A nrPDB 302 1e-82 1GVZ-A nrPDB 300 4e-82 2TLD-E nrPDB 296 6e-81 1FXY-A nrPDB 296 9e-81 3BSQ-A nrPDB 288 2e-78 2EEK-A nrPDB 286 1e-77 2PSX-A nrPDB 284 2e-77 4GSO-A nrPDB 283 6e-77 5ZFH-A nrPDB 281 2e-76 6QHB-A nrPDB 279 1e-75 1EUF-A nrPDB 279 1e-75 1FI8-A nrPDB 272 1e-73 4E7N-A nrPDB 270 3e-73 2AIQ-A nrPDB 270 3e-73 1OP0-A nrPDB 269 9e-73 5TJX-A nrPDB 267 3e-72 1X7A-C nrPDB 266 5e-72 3LC3-A nrPDB 266 6e-72 6I44-A nrPDB 266 7e-72 1BQY-A nrPDB 265 2e-71 3S69-A nrPDB 265 2e-71 2BDH-A nrPDB 263 5e-71 5LPF-A nrPDB 262 1e-70 5UGG-A nrPDB 262 1e-70 4DUR-A nrPDB 261 2e-70 3T2N-A nrPDB 261 2e-70 3K65-B nrPDB 260 5e-70 3NXP-A nrPDB 260 6e-70 2F83-A nrPDB 259 7e-70 5GVT-A nrPDB 259 7e-70 1MKW-K nrPDB 259 1e-69 4NZQ-A nrPDB 258 2e-69 3S9B-A nrPDB 257 2e-69 2CGA-A nrPDB 257 4e-69 3E0N-B nrPDB 257 4e-69 1IAU-A nrPDB 256 5e-69 3DFJ-A nrPDB 256 7e-69 1FDP-A nrPDB 255 9e-69 1NN6-A nrPDB 255 1e-68 1P57-B nrPDB 255 1e-68 1BRU-P nrPDB 255 2e-68 3W94-A nrPDB 254 2e-68 4DGJ-A nrPDB 253 6e-68 2F91-A nrPDB 252 1e-67 2OCV-B nrPDB 252 2e-67 1EKB-B nrPDB 251 2e-67 3TK9-A nrPDB 251 2e-67 1KIG-H nrPDB 250 4e-67 1ETT-H nrPDB 250 6e-67 3G01-A nrPDB 249 9e-67 1VR1-H nrPDB 248 2e-66 1SC8-U nrPDB 247 3e-66 5FCR-A nrPDB 246 9e-66 4Z6A-H nrPDB 245 1e-65 1C5M-D nrPDB 245 1e-65 3F6U-H nrPDB 245 1e-65 1FIZ-A nrPDB 245 2e-65 4MPW-A nrPDB 244 2e-65 1YC0-A nrPDB 244 3e-65 2OQ5-A nrPDB 243 6e-65 6AOD-C nrPDB 243 7e-65 5XRF-A nrPDB 242 1e-64 5LHN-A nrPDB 242 1e-64 3P8G-A nrPDB 242 2e-64 1MZD-A nrPDB 241 2e-64 4H4F-A nrPDB 241 2e-64 1KYN-A nrPDB 241 2e-64 1ORF-A nrPDB 241 2e-64 1BDA-A nrPDB 240 4e-64 1LTO-A nrPDB 240 6e-64 5TO3-B nrPDB 238 2e-63 2V35-A nrPDB 238 2e-63 2XRC-A nrPDB 238 2e-63 1PYT-D nrPDB 238 2e-63 1FIW-A nrPDB 237 3e-63 1AZZ-A nrPDB 237 3e-63 2RDL-A nrPDB 237 5e-63 2R0L-A nrPDB 236 7e-63 4XDE-A nrPDB 235 1e-62 1A5I-A nrPDB 234 3e-62 1Q3X-A nrPDB 234 4e-62 3RP2-A nrPDB 234 5e-62 4KKD-A nrPDB 233 5e-62 4Q7Y-A nrPDB 233 5e-62 1FUJ-A nrPDB 233 5e-62 2XXL-A nrPDB 232 1e-61 4IGD-A nrPDB 232 1e-61 1ZJK-A nrPDB 230 3e-61 4IW4-E nrPDB 230 7e-61 4FXG-H nrPDB 229 1e-60 1ELT-A nrPDB 228 2e-60 4DJZ-B nrPDB 227 5e-60 4BXW-A nrPDB 226 1e-59 1FON-A nrPDB 225 1e-59 2ZKS-A nrPDB 224 4e-59 5O32-I nrPDB 217 3e-57 5UBM-A nrPDB 214 3e-56 1ELV-A nrPDB 214 3e-56 1YM0-A nrPDB 210 5e-55 5KWM-A nrPDB 210 6e-55 1EQ9-A nrPDB 209 1e-54 4J1Y-A nrPDB 208 1e-54 2B9L-A nrPDB 207 5e-54 1PPF-E nrPDB 207 5e-54 1GPZ-A nrPDB 207 6e-54 2QY0-B nrPDB 206 9e-54 1MD7-A nrPDB 205 1e-53 2OLG-A nrPDB 205 1e-53 1AE5-A nrPDB 205 1e-53 2PKA-B nrPDB 205 2e-53 4LK4-A nrPDB 199 1e-51 4X0L-C nrPDB 199 1e-51 4WJG-C nrPDB 198 2e-51 1PQ7-A nrPDB 198 2e-51 4F4O-C nrPDB 195 1e-50 6BQM-A nrPDB 195 2e-50 2HLC-A nrPDB 192 1e-49 1SI5-H nrPDB 192 2e-49 2ASU-B nrPDB 191 2e-49 3I77-A nrPDB 191 3e-49 2FMJ-A nrPDB 187 3e-48 3BEU-A nrPDB 187 5e-48 5XW8-A nrPDB 175 2e-44 3H7T-A nrPDB 173 5e-44 1M9U-A nrPDB 169 1e-42 3H7O-A nrPDB 166 9e-42 1AKS-B nrPDB 150 5e-37 1RIW-B nrPDB 146 1e-35 3F1S-B nrPDB 143 7e-35 2WIN-I nrPDB 142 1e-34 1BBR-H nrPDB 141 2e-34 2JET-B nrPDB 141 2e-34 3VGC-B nrPDB 141 2e-34 1DLE-A nrPDB 140 5e-34 3H5C-B nrPDB 140 5e-34 2OK5-A nrPDB 138 2e-33 2I6S-A nrPDB 124 4e-29 2KAI-A nrPDB 124 5e-29 1BBR-E nrPDB 118 2e-27 2HNT-F nrPDB 118 2e-27 3RU4-E nrPDB 115 2e-26 2JET-C nrPDB 114 3e-26 1EPT-B nrPDB 104 4e-23 2HNT-C nrPDB 75 2e-14 Sequences not found previously or not previously below threshold: 2HNT-E nrPDB 74 6e-14 1P3E-A nrPDB 36 0.014 2EA3-A nrPDB 35 0.035 2PFE-A nrPDB 35 0.041 2OUA-A nrPDB 33 0.14 5ILB-A nrPDB 33 0.16 4FLN-A nrPDB 33 0.16 2SFA-A nrPDB 33 0.18 5JYK-A nrPDB 32 0.33 5ILA-A nrPDB 31 0.46 3LT3-A nrPDB 31 0.49 2SGA-A nrPDB 31 0.59 5MM8-A nrPDB 31 0.61 5MRT-A nrPDB 30 1.0 3QO6-A nrPDB 29 1.8 4NSY-A nrPDB 29 1.9 4FVB-A nrPDB 29 1.9 3W95-A nrPDB 29 1.9 1HPG-A nrPDB 29 2.6 2M5T-A nrPDB 28 3.0 1DUE-A nrPDB 28 3.0 2HRV-A nrPDB 28 3.7 1PNF-A nrPDB 28 3.8 5MRR-A nrPDB 28 4.9 4B6E-A nrPDB 28 6.4 4NWK-A nrPDB 27 7.0 6FE6-A nrPDB 27 8.0 6C2N-A nrPDB 27 8.3 4IC5-A nrPDB 27 8.6 4U01-A nrPDB 27 8.8 4K8B-A nrPDB 27 9.0 >1AO5-A nrPDB Length = 237 Score = 348 bits (894), Expect = 1e-96, Method: Composition-based stats. Identities = 235/237 (99%), Positives = 237/237 (100%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 VVGGFNC+KNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE Sbjct: 1 VVGGFNCEKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFS+DLMLLRLSKPADITDVVKPIALPTK Sbjct: 61 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSDDLMLLRLSKPADITDVVKPIALPTK 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG Sbjct: 121 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA Sbjct: 181 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 237 >1SGF-G nrPDB Length = 237 Score = 347 bits (891), Expect = 3e-96, Method: Composition-based stats. Identities = 169/236 (71%), Positives = 194/236 (82%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGGF C+KNSQPW VAVY +++CGGVLLD NWVLTAAHCY D Y+VWLGKN LF++E Sbjct: 1 IVGGFKCEKNSQPWHVAVYRYTQYLCGGVLLDPNWVLTAAHCYDDNYKVWLGKNNLFKDE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 PSAQHR VSK+ PHPGFNMSL+ D+SNDLMLLRLSKPADITD VKPI LPT+ Sbjct: 61 PSAQHRFVSKAIPHPGFNMSLMRKHIRFLEYDYSNDLMLLRLSKPADITDTVKPITLPTE 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPK GS CLASGWGSITPT++Q DDL CV + LLPNE+CAK +++KVTD MLCAGEM G Sbjct: 121 EPKLGSTCLASGWGSITPTKFQFTDDLYCVNLKLLPNEDCAKAHIEKVTDAMLCAGEMDG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKDTC+ DSGGPLICDG+LQG TS+G PCG+P +P +YT L KF SWIKDTM KN Sbjct: 181 GKDTCKGDSGGPLICDGVLQGITSWGHTPCGEPDMPGVYTKLNKFTSWIKDTMAKN 236 >4NFE-A nrPDB Length = 237 Score = 337 bits (865), Expect = 3e-93, Method: Composition-based stats. Identities = 135/236 (57%), Positives = 169/236 (71%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+K+SQPWQVAVY CGGVL+ WVLTAAHC +VWLG++ LF+ E Sbjct: 1 IVGGWECEKHSQPWQVAVYSHGWAHCGGVLVHPQWVLTAAHCLKKNSQVWLGRHNLFEPE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q VS SFPHP +NMSLL Q++ P D S+DLMLLRLS+PA ITDVVK + LPT+ Sbjct: 61 DTGQRVPVSHSFPHPLYNMSLLKHQSLRPDEDSSHDLMLLRLSEPAKITDVVKVLGLPTQ 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EP G+ C ASGWGSI P + +P LQCV + LL N+ CA+ Y +KVT+ MLCAG G Sbjct: 121 EPALGTTCYASGWGSIEPEEFLRPRSLQCVSLHLLSNDMCARAYSEKVTEFMLCAGLWTG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKDTC DSGGPL+C+G+LQG TS+GP PC P PA+YT ++ + WIKDT+ N Sbjct: 181 GKDTCGGDSGGPLVCNGVLQGITSWGPEPCALPEKPAVYTKVVHYRKWIKDTIAAN 236 >1SPJ-A nrPDB Length = 238 Score = 333 bits (854), Expect = 6e-92, Method: Composition-based stats. Identities = 135/238 (56%), Positives = 177/238 (74%), Gaps = 1/238 (0%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+++SQPWQ A+Y+ CGG+L+ R WVLTAAHC D Y++WLG++ LF +E Sbjct: 1 IVGGWECEQHSQPWQAALYHFSTFQCGGILVHRQWVLTAAHCISDNYQLWLGRHNLFDDE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA-DITDVVKPIALPT 143 +AQ VS+SFPHPGFNMSLL T D+S+DLMLLRL++PA ITD VK + LPT Sbjct: 61 NTAQFVHVSESFPHPGFNMSLLENHTRQADEDYSHDLMLLRLTEPADTITDAVKVVELPT 120 Query: 144 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 203 +EP+ GS CLASGWGSI P + PDDLQCV + +LPN+ C K ++QKVTD MLC G + Sbjct: 121 EEPEVGSTCLASGWGSIEPENFSFPDDLQCVDLKILPNDECKKAHVQKVTDFMLCVGHLE 180 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GGKDTC DSGGPL+CDG+LQG TS+G VPCG P P++ ++ + WI+DT+ +N+ Sbjct: 181 GGKDTCVGDSGGPLMCDGVLQGVTSWGYVPCGTPNKPSVAVRVLSYVKWIEDTIAENS 238 >1SGF-A nrPDB Length = 240 Score = 328 bits (842), Expect = 1e-90, Method: Composition-based stats. Identities = 169/244 (69%), Positives = 195/244 (79%), Gaps = 5/244 (2%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLG 76 AAPP+QS+V +C+ NSQPW VAVY ++ CGGVLLDRNWVLTAAHCY D+Y+VWLG Sbjct: 1 AAPPVQSQV----DCE-NSQPWHVAVYRFNKYQCGGVLLDRNWVLTAAHCYNDKYQVWLG 55 Query: 77 KNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVV 136 KN ++EPS QHRLVSK+ PHP FNMSLL T P D+SNDLMLLRLSKPADITDVV Sbjct: 56 KNNFLEDEPSDQHRLVSKAIPHPDFNMSLLNEHTPQPEDDYSNDLMLLRLSKPADITDVV 115 Query: 137 KPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 KPI LPT+EPK GS CLASGWGS TP +++ PDDLQCV + LLPNE+C K + KVTD M Sbjct: 116 KPITLPTEEPKLGSTCLASGWGSTTPIKFKYPDDLQCVNLKLLPNEDCDKAHEMKVTDAM 175 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 LCAGEM GG TC DSGGPLICDGILQG TS+GP PCG+P P++YT LIKF+SWI++T Sbjct: 176 LCAGEMDGGSYTCEHDSGGPLICDGILQGITSWGPEPCGEPTEPSVYTKLIKFSSWIRET 235 Query: 257 MMKN 260 M N Sbjct: 236 MANN 239 >5FXL-A nrPDB Length = 246 Score = 328 bits (841), Expect = 1e-90, Method: Composition-based stats. Identities = 95/256 (37%), Positives = 144/256 (56%), Gaps = 15/256 (5%) Query: 7 FLALSLGGIDAAPPLQS--RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAA 64 F+ L+L G A P+ ++VGG+ C N+ P+QV++ H CGG L++ WV++AA Sbjct: 4 FIFLALLGAAVAFPVDDDDKIVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAA 62 Query: 65 HCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLL 124 HCY +V LG++ + E + Q SKS HP +N + L +ND+ML+ Sbjct: 63 HCYKSGIQVRLGEDNINVVEGNEQFISASKSIVHPSYNSNTL-----------NNDIMLI 111 Query: 125 RLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 +L A + V I+LPT G++CL SGWG+ + PD L+C+ +L + +C Sbjct: 112 KLKSAASLNSRVASISLPTSCASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSC 171 Query: 185 AKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYT 244 Y ++T M CAG + GGKD+C+ DSGGP++C G LQG S+G C + P +YT Sbjct: 172 KSAYPGQITSNMFCAGYLEGGKDSCQGDSGGPVVCSGKLQGIVSWGS-GCAQKNKPGVYT 230 Query: 245 NLIKFNSWIKDTMMKN 260 + + SWIK T+ N Sbjct: 231 KVCNYVSWIKQTIASN 246 >3QUM-P nrPDB Length = 237 Score = 323 bits (829), Expect = 4e-89, Method: Composition-based stats. Identities = 124/236 (52%), Positives = 166/236 (70%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+K+SQPWQV V + +CGGVL+ WVLTAAHC ++ + LG++ LF E Sbjct: 1 IVGGWECEKHSQPWQVLVASRGRAVCGGVLVHPQWVLTAAHCIRNKSVILLGRHSLFHPE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q VS SFPHP ++MSLL + + PG D S+DLMLLRLS+PA++TD VK + LPT+ Sbjct: 61 DTGQVFQVSHSFPHPLYDMSLLKNRFLRPGDDSSHDLMLLRLSEPAELTDAVKVMDLPTQ 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EP G+ C ASGWGSI P + P LQCV + ++ N+ CA+V+ QKVT MLCAG G Sbjct: 121 EPALGTTCYASGWGSIEPEEFLTPKKLQCVDLHVISNDVCAQVHPQKVTKFMLCAGRWTG 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GK TC DSGGPL+C+G+LQG TS+G PC P P++YT ++ + WIKDT++ N Sbjct: 181 GKSTCSGDSGGPLVCNGVLQGITSWGSEPCALPERPSLYTKVVHYRKWIKDTIVAN 236 >1F7Z-A nrPDB Length = 233 Score = 322 bits (825), Expect = 1e-88, Method: Composition-based stats. Identities = 92/236 (38%), Positives = 139/236 (58%), Gaps = 13/236 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C++NS P+QV++ H CGG L++ WV++AAHCY + +V LG++ + E Sbjct: 11 IVGGYTCQENSVPYQVSLN-SGYHFCGGSLINDQWVVSAAHCYKSRIQVRLGEHNINVLE 69 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q +K HP F+ L +ND+ML++LS P + V +ALP+ Sbjct: 70 GNEQFVNAAKIIKHPNFDRKTL-----------NNDIMLIKLSSPVKLNARVATVALPSS 118 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 G++CL SGWG+ + +PD LQC+ LLP +C Y K+TD M+C G + G Sbjct: 119 CAPAGTQCLISGWGNTLSSGVNEPDLLQCLDAPLLPQADCEASYPGKITDNMVCVGFLEG 178 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKD+C+ DSGGP++C+G LQG S+G C P P +YT + + WI+DT+ N Sbjct: 179 GKDSCQGDSGGPVVCNGELQGIVSWG-YGCALPDNPGVYTKVCNYVDWIQDTIAAN 233 >4AN7-A nrPDB Length = 231 Score = 321 bits (823), Expect = 2e-88, Method: Composition-based stats. Identities = 86/239 (35%), Positives = 134/239 (56%), Gaps = 13/239 (5%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++VGG+ C NS P+QV++ H CGG L++ WV++AAHCY + +V LG++ + Sbjct: 6 DDKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNID 64 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 E + Q +K HP FN G ND+ML++LS PA + V ++L Sbjct: 65 VLEGNEQFINAAKIITHPNFN-----------GNTLDNDIMLIKLSSPATLNSRVATVSL 113 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGE 201 P G++CL SGWG+ + P LQC+ +L + +C Y ++T M+C G Sbjct: 114 PRSCAAAGTECLISGWGNTKSSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGF 173 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 + GGKD+C+ DSGGP++C+G LQG S+G C + P +YT + + +WI+ T+ N Sbjct: 174 LEGGKDSCQGDSGGPVVCNGQLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 231 >5C67-A nrPDB Length = 224 Score = 319 bits (818), Expect = 7e-88, Method: Composition-based stats. Identities = 91/237 (38%), Positives = 135/237 (56%), Gaps = 13/237 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C++NS P+QV++ H CGG L+ WV++AAHCY + +V LG++ + E Sbjct: 1 IVGGYTCEENSLPYQVSLN-SGSHFCGGSLISEQWVVSAAHCYKTRIQVRLGEHNIKVLE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q +K HP +N L ND+ML++LS PA I V I+LPT Sbjct: 60 GNEQFINAAKIIRHPKYNRDTL-----------DNDIMLIKLSSPAVINARVSTISLPTA 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P G++CL SGWG+ PD+L+C+ +L C Y K+T+ M C G + G Sbjct: 109 PPAAGTECLISGWGNTLSFGADYPDELKCLDAPVLTQAECKASYPGKITNSMFCVGFLEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKD+C+ D+GGP++C+G LQG S+G C P +YT + + WIKDT+ N+ Sbjct: 169 GKDSCQRDAGGPVVCNGQLQGVVSWGH-GCAWKNRPGVYTKVYNYVDWIKDTIAANS 224 >4WWY-A nrPDB Length = 224 Score = 319 bits (818), Expect = 8e-88, Method: Composition-based stats. Identities = 91/237 (38%), Positives = 137/237 (57%), Gaps = 13/237 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+NC++NS P+QV++ H CGG L++ WV++A HCY + +V LG++ + E Sbjct: 1 IVGGYNCEENSVPYQVSLN-SGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q +K HP ++ L +ND+ML++LS A I V I+LPT Sbjct: 60 GNEQFINAAKIIRHPQYDRKTL-----------NNDIMLIKLSSRAVINAHVSTISLPTA 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P G+KCL SGWG+ + PD+LQC+ +L C Y K+T M C G + G Sbjct: 109 PPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKD+C+ DSGGP++C+G LQG S+G C + P +YT + + WIK+T+ N+ Sbjct: 169 GKDSCQRDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAANS 224 >1TON-A nrPDB Length = 235 Score = 315 bits (808), Expect = 1e-86, Method: Composition-based stats. Identities = 148/236 (62%), Positives = 170/236 (72%), Gaps = 2/236 (0%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+KNSQPWQVAV E++CGGVL+D +WV+TAAHCY + Y+V LG+N LF++E Sbjct: 1 IVGGYKCEKNSQPWQVAVI--NEYLCGGVLIDPSWVITAAHCYSNNYQVLLGRNNLFKDE 58 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 P AQ RLV +SF HP + ++ T P D SNDLMLL LS+PADIT VK I LPTK Sbjct: 59 PFAQRRLVRQSFRHPDYIPLIVTNDTEQPVHDHSNDLMLLHLSEPADITGGVKVIDLPTK 118 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPK GS CLASGWGS P+ DLQCV I LL NE C + Y VTDVMLCAGEM G Sbjct: 119 EPKVGSTCLASGWGSTNPSEMVVSHDLQCVNIHLLSNEKCIETYKDNVTDVMLCAGEMEG 178 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKDTC DSGGPLICDG+LQG TS G PC KP PAIY LIKF SWIK M +N Sbjct: 179 GKDTCAGDSGGPLICDGVLQGITSGGATPCAKPKTPAIYAKLIKFTSWIKKVMKEN 234 >1A0J-A nrPDB Length = 223 Score = 313 bits (803), Expect = 4e-86, Method: Composition-based stats. Identities = 89/236 (37%), Positives = 136/236 (57%), Gaps = 13/236 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C+KNS +Q ++ H CGG L+ WV++AAHCY + +V LG++ + E Sbjct: 1 IVGGYECRKNSASYQASLQ-SGYHFCGGSLISSTWVVSAAHCYKSRIQVRLGEHNIAVNE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q K HP +N + ND+ML++LSKPA + V +ALP+ Sbjct: 60 GTEQFIDSVKVIMHPSYNSR-----------NLDNDIMLIKLSKPASLNSYVSTVALPSS 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 G++CL SGWG+++ + PD L+C+ + +L + +C Y ++T M CAG M G Sbjct: 109 CASSGTRCLVSGWGNLSGSSSNYPDTLRCLDLPILSSSSCNSAYPGQITSNMFCAGFMEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GKD+C+ DSGGP++C+G LQG S+G C + P +YT + + SWI TM N Sbjct: 169 GKDSCQGDSGGPVVCNGQLQGVVSWG-YGCAQRNKPGVYTKVCNYRSWISSTMSSN 223 >1UTJ-A nrPDB Length = 242 Score = 312 bits (801), Expect = 7e-86, Method: Composition-based stats. Identities = 97/256 (37%), Positives = 143/256 (55%), Gaps = 15/256 (5%) Query: 4 LILFLALSLGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTA 63 +I + + L G A ++VGG+ CK SQP QV++ H CGG L++ NWV++A Sbjct: 1 MISLVFVLLIGAAFATE-DDKIVGGYECKPYSQPHQVSLN-SGYHFCGGSLVNENWVVSA 58 Query: 64 AHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLML 123 AHCY + EV LG++ + E S Q S+ HP ++ + ND+ML Sbjct: 59 AHCYKSRVEVRLGEHNIKVTEGSEQFISSSRVIRHPNYSS-----------YNIDNDIML 107 Query: 124 LRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNEN 183 ++LSKPA + V+P+ALPT G+ C SGWG+ + + LQC+ I +L + Sbjct: 108 IKLSKPATLNTYVQPVALPTSCAPAGTMCTVSGWGNTMSSTAD-SNKLQCLNIPILSYSD 166 Query: 184 CAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIY 243 C Y +T+ M CAG + GGKD+C+ DSGGP++C+G LQG S+G C +PG P +Y Sbjct: 167 CNNSYPGMITNAMFCAGYLEGGKDSCQGDSGGPVVCNGELQGVVSWG-YGCAEPGNPGVY 225 Query: 244 TNLIKFNSWIKDTMMK 259 + FN W+ TM Sbjct: 226 AKVCIFNDWLTSTMAS 241 >5MS3-A nrPDB Length = 228 Score = 304 bits (778), Expect = 4e-83, Method: Composition-based stats. Identities = 102/237 (43%), Positives = 141/237 (59%), Gaps = 9/237 (3%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C+ +SQPWQ A++ ++ +CGGVL+ NWVLTAAHC +Y V LG + L ++ Sbjct: 1 VLGGHECQPHSQPWQAALFQGQQLLCGGVLVGGNWVLTAAHCKKPKYTVRLGDHSLQNKD 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q V +S PHP +N S + D ++DLMLL+L A + VKPI+L Sbjct: 61 GPEQEIPVVQSIPHPCYNSSDV--------EDHNHDLMLLQLRDQASLGSKVKPISLADH 112 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 +PG KC SGWG++T R PD L C + + P + C Y ++TD M+CAG Sbjct: 113 CTQPGQKCTVSGWGTVTSPRENFPDTLNCAEVKIFPQKKCEDAYPGQITDGMVCAG-SSK 171 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 G DTC+ DSGGPL+CDG LQG TS+G PCG+ P +YTN+ ++ WIK + Sbjct: 172 GADTCQGDSGGPLVCDGALQGITSWGSDPCGRSDKPGVYTNICRYLDWIKKIIGSKG 228 >1NPM-A nrPDB Length = 225 Score = 302 bits (774), Expect = 1e-82, Method: Composition-based stats. Identities = 100/233 (42%), Positives = 139/233 (59%), Gaps = 9/233 (3%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++ G C +SQPWQ A++ + ICGGVL+ WVLTAAHC +Y V LG + L + Sbjct: 1 ILEGRECIPHSQPWQAALFQGERLICGGVLVGDRWVLTAAHCKKQKYSVRLGDHSLQSRD 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q V++S HP +N S D S+D+ML+RL A++ D VKP+ L Sbjct: 61 QPEQEIQVAQSIQHPCYNNS--------NPEDHSHDIMLIRLQNSANLGDKVKPVQLANL 112 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 PK G KC+ SGWG++T + P+ L C + + C + Y K+T+ M+CAG Sbjct: 113 CPKVGQKCIISGWGTVTSPQENFPNTLNCAEVKIYSQNKCERAYPGKITEGMVCAG-SSN 171 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G DTC+ DSGGPL+CDG+LQG TS+G PCGKP P +YT + ++ +WIK TM Sbjct: 172 GADTCQGDSGGPLVCDGMLQGITSWGSDPCGKPEKPGVYTKICRYTTWIKKTM 224 >1GVZ-A nrPDB Length = 237 Score = 300 bits (769), Expect = 4e-82, Method: Composition-based stats. Identities = 113/237 (47%), Positives = 154/237 (64%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++GG+ C+K+S+PWQVAVY+Q CGGVL+ WVLTAAHC D Y++WLG++ L ++E Sbjct: 1 IIGGWECEKHSKPWQVAVYHQGHFQCGGVLVHPQWVLTAAHCMSDDYQIWLGRHNLSKDE 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 +AQ VS SF P F++SLL + + P D S+DLMLLRL++PA ITD VK + LPT+ Sbjct: 61 DTAQFHQVSDSFLDPQFDLSLLKKKYLRPYDDISHDLMLLRLAQPARITDAVKILDLPTQ 120 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 EPK GS C SGWG I+ + LQCV + L NE CA+ Y +K+T+ +LCA Sbjct: 121 EPKLGSTCYTSGWGLISTFTNRGSGTLQCVELRLQSNEKCARAYPEKMTEFVLCATHRDD 180 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 C DSGG LICDG+ QG TS+G C ++T ++ WIK+T+ KN+ Sbjct: 181 SGSICLGDSGGALICDGVFQGITSWGYSECADFNDNFVFTKVMPHKKWIKETIEKNS 237 >2TLD-E nrPDB Length = 220 Score = 296 bits (759), Expect = 6e-81, Method: Composition-based stats. Identities = 89/236 (37%), Positives = 132/236 (55%), Gaps = 16/236 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C N+ P+QV++ H CGG L++ WV++AAHCY +V LG++ + E Sbjct: 1 IVGGYTCGANTVPYQVSLN-SGYHFCGGSLINSQWVVSAAHCYKSGIQVRLGEDNINVVE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q SKS HP +N + L +ND+ML++L A + V I+LPT Sbjct: 60 GNEQFISASKSIVHPSYNSNTL-----------NNDIMLIKLKSAASLNSRVASISLPTS 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 G++CL SGWG+ + PD L+C+ +L + +C Y ++T M CAG GG Sbjct: 109 CASAGTQCLISGWGNTKSSGTSYPDVLKCLKAPILSDSSCKSAYPGQITSNMFCAGLEGG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 D+C+ DSGGP++C G LQG S+G C K P +YT + + SWIK T+ N Sbjct: 169 --DSCQGDSGGPVVCSGKLQGIVSWGS-GCAK-NKPGVYTKVCNYVSWIKQTIASN 220 >1FXY-A nrPDB Length = 228 Score = 296 bits (757), Expect = 9e-81, Method: Composition-based stats. Identities = 86/240 (35%), Positives = 122/240 (50%), Gaps = 15/240 (6%) Query: 25 VVGGFNCKKNSQPWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYV--DQYEVWLGKNKLF 81 +VGG+NCK PWQ + + E CGG +L ++LTAAHC +++V +G Sbjct: 1 IVGGYNCKDGEVPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 QEE V H F + D+ +LRL P V P +L Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTK-----------ETYDFDIAVLRLKTPITFRMNVAPASL 109 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGE 201 PT P G+KCL SGWG+ + PD+LQC+ +L C Y K+T M C G Sbjct: 110 PTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGF 169 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 + GGKD+C+ DSGGP++C+G LQG S+G C + P +YT + + WIK+T+ N+ Sbjct: 170 LEGGKDSCQGDSGGPVVCNGQLQGVVSWGD-GCAQKNKPGVYTKVYNYVKWIKNTIAANS 228 >3BSQ-A nrPDB Length = 227 Score = 288 bits (737), Expect = 2e-78, Method: Composition-based stats. Identities = 98/234 (41%), Positives = 136/234 (58%), Gaps = 13/234 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++ G C + S PWQVA+ + CGGVL++ WVLTAAHC +++Y V LG + L + Sbjct: 1 IIDGAPCARGSHPWQVALLSGNQLHCGGVLVNERWVLTAAHCKMNEYTVHLGSDTLG--D 58 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 AQ SKSF HPG++ + NDLML++L+ A ++ +VK + LP++ Sbjct: 59 RRAQRIKASKSFRHPGYSTQTHV-----------NDLMLVKLNSQARLSSMVKKVRLPSR 107 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 PG+ C SGWG+ T P DL CV + L+ ++C KVY + + MLCAG Sbjct: 108 CEPPGTTCTVSGWGTTTSPDVTFPSDLMCVDVKLISPQDCTKVYKDLLENSMLCAGIPDS 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 K+ C DSGGPL+C G LQG S+G PCG+P P +YT + KF WI DTM Sbjct: 168 KKNACNGDSGGPLVCRGTLQGLVSWGTFPCGQPNDPGVYTQVCKFTKWINDTMK 221 >2EEK-A nrPDB Length = 220 Score = 286 bits (731), Expect = 1e-77, Method: Composition-based stats. Identities = 84/234 (35%), Positives = 133/234 (56%), Gaps = 14/234 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG+ C K+SQ QV++ H CGG L+ ++WV++AAHCY V LG++ + E Sbjct: 1 IVGGYECTKHSQAHQVSLN-SGYHFCGGSLVSKDWVVSAAHCYKSVLRVRLGEHHIRVNE 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 + Q+ S HP ++ + +ND+ML++L+KPA + V +ALPT+ Sbjct: 60 GTEQYISSSSVIRHPNYSS-----------YNINNDIMLIKLTKPATLNQYVHAVALPTE 108 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 + C SGWG+ + D LQC+ + +L + +CA Y +T M CAG + G Sbjct: 109 CAADATMCTVSGWGNTMSSVAD-GDKLQCLSLPILSHADCANSYPGMITQSMFCAGYLEG 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 GKD+C+ DSGGP++C+G+LQG S+G C + P +Y + + W++DTM Sbjct: 168 GKDSCQGDSGGPVVCNGVLQGVVSWG-YGCAERDHPGVYAKVCVLSGWVRDTMA 220 >2PSX-A nrPDB Length = 227 Score = 284 bits (728), Expect = 2e-77, Method: Composition-based stats. Identities = 92/239 (38%), Positives = 136/239 (56%), Gaps = 14/239 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ-KEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF-Q 82 ++ G +C ++QPWQ A+ + + CG VL+ W+LTAAHC + V LG L Sbjct: 1 IINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPV 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 E Q KS PHPG++ SNDLML++L++ T V+PI + Sbjct: 61 YESGQQMFQGVKSIPHPGYSH-----------PGHSNDLMLIKLNRRIRPTKDVRPINVS 109 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEM 202 + P G+KCL SGWG+ + P LQC+ I++L + C Y +++ D M CAG+ Sbjct: 110 SHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGD- 168 Query: 203 GGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 G+D+C+ DSGGP++C+G LQG S+G PC +P P +YTNL KF WI++T+ N+ Sbjct: 169 KAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS 227 >4GSO-A nrPDB Length = 232 Score = 283 bits (724), Expect = 6e-77, Method: Composition-based stats. Identities = 87/237 (36%), Positives = 118/237 (49%), Gaps = 11/237 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N P+ +Y + CG L+++ WV+TAAHC +++ LG + Sbjct: 1 VLGGDECDINEHPFLAFLYSHG-YFCGLTLINQEWVVTAAHCDSTNFQMQLGVHSKKVLN 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P NMS ++ D+ML++L KP + + P++LP+ Sbjct: 60 EDEQTRNPKEKFICPNKNMSEVL----------DKDIMLIKLDKPISNSKHIAPLSLPSN 109 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P GS C GWGSIT PD C I L+ E C Y LCAG + G Sbjct: 110 PPSVGSVCRIMGWGSITIPNETYPDVPYCANINLVDYEVCQGAYNGLPAKTTLCAGVLEG 169 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKDTC DSGGPLIC+G QG SYG CG+ P IYTN+ + WI+ + N Sbjct: 170 GKDTCVGDSGGPLICNGQFQGIVSYGAHSCGQGPKPGIYTNVFDYTDWIQRNIAGNT 226 >5ZFH-A nrPDB Length = 224 Score = 281 bits (720), Expect = 2e-76, Method: Composition-based stats. Identities = 95/234 (40%), Positives = 135/234 (57%), Gaps = 13/234 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++ G+ CK+ S PWQVA+ + CGGVL+D+ WVLTAAHC + QY+V LG +K+ + Sbjct: 1 IIDGYKCKEGSHPWQVALLKGNQLHCGGVLVDKYWVLTAAHCKMGQYQVQLGSDKIGDQ- 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 SAQ +KSF HPG++ + ND+ML+RL +P ++ V+ + LP Sbjct: 60 -SAQKIKATKSFRHPGYSTKTHV-----------NDIMLVRLDEPVKMSSKVEAVQLPEH 107 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 PG+ C SGWG+ T P DL C + L+ + C KVY + MLCAG Sbjct: 108 CEPPGTSCTVSGWGTTTSPDVTFPSDLMCSDVKLISSRECKKVYKDLLGKTMLCAGIPDS 167 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 +TC DSGGPL+C+ LQG S+G PCG+P P +YT + K+ W+ +TM Sbjct: 168 KTNTCNGDSGGPLVCNDTLQGLVSWGTYPCGQPNDPGVYTQVCKYKRWVMETMK 221 >6QHB-A nrPDB Length = 223 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 88/235 (37%), Positives = 131/235 (55%), Gaps = 13/235 (5%) Query: 26 VGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEP 85 V G C K S P+Q A+Y +CGGVL+ WVLTAAHC +V+LGK+ L Q+E Sbjct: 2 VHGGPCDKTSHPYQAALYTSGHLLCGGVLIHPLWVLTAAHCKKPNLQVFLGKHNLGQQES 61 Query: 86 SAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKE 145 S + V ++ HP ++ A D+MLLRL++PA ++++++P+ L Sbjct: 62 SQEQSSVVRAVIHPDYD-----------AASHDQDIMLLRLARPAKLSELIQPLPLERDC 110 Query: 146 PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGG 205 + C GWG PD +QC +I L+ E C Y ++T MLCAG+ G Sbjct: 111 SAQTTSCHILGWGKTAD--GDFPDTIQCAYIHLVSREECEHAYPGQITQNMLCAGDEKYG 168 Query: 206 KDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 KD+C+ DSGGPL+C L+G S+G +PCG P +YTN+ ++ +WI+ T+ Sbjct: 169 KDSCQGDSGGPLVCGDHLRGLVSWGNIPCGSKEKPGVYTNVCRYTNWIQKTIQAK 223 >1EUF-A nrPDB Length = 227 Score = 279 bits (713), Expect = 1e-75, Method: Composition-based stats. Identities = 86/240 (35%), Positives = 124/240 (51%), Gaps = 20/240 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG K +S+P+ + ++ K HICGG L+ ++VLTAAHC V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAFLLFKTSGKSHICGGFLVREDFVLTAAHCLGSSINVTLGAHNIM 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + E + Q V + PHP +N L +ND+MLL+L++ ADITD V PI L Sbjct: 61 ERERTQQVIPVRRPIPHPDYNDETL-----------ANDIMLLKLTRKADITDKVSPINL 109 Query: 142 PT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCA 199 P E KPG C +GWG + D LQ V + + E C + + +CA Sbjct: 110 PRSLAEVKPGMMCSVAGWGRL-GVNMPSTDKLQEVDLEVQSEEKCIARFKNYIPFTQICA 168 Query: 200 GEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 G+ K++ DSGGPL+C+G+ QG SYG P +YT + F SWI TM + Sbjct: 169 GDPSKRKNSFSGDSGGPLVCNGVAQGIVSYGR---NDGTTPDVYTRISSFLSWIHSTMRR 225 >1FI8-A nrPDB Length = 228 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 80/243 (32%), Positives = 118/243 (48%), Gaps = 22/243 (9%) Query: 25 VVGGFNCKKNSQPWQVAVY----YQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG K +S+P+ + Y CGG L+ ++VLTAAHC + +V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAYLQIMDEYSGSKKCGGFLIREDFVLTAAHCSGSKIQVTLGAHNI 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 ++E Q V K PHP +N + SND+MLL+L A + VKP+ Sbjct: 61 KEQEKMQQIIPVVKIIPHPAYNSKTI-----------SNDIMLLKLKSKAKRSSAVKPLN 109 Query: 141 LPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV-TDVML 197 LP + KPG C +GWG + P + D LQ V +T+ ++ C + Sbjct: 110 LPRRNVKVKPGDVCYVAGWGKLGP-MGKYSDTLQEVELTVQEDQKCESYLKNYFDKANEI 168 Query: 198 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 CAG+ + + R DSGGPL+C + G SYG P +T + F SWIK TM Sbjct: 169 CAGDPKIKRASFRGDSGGPLVCKKVAAGIVSYGQ---NDGSTPRAFTKVSTFLSWIKKTM 225 Query: 258 MKN 260 K+ Sbjct: 226 KKS 228 >4E7N-A nrPDB Length = 238 Score = 270 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 87/242 (35%), Positives = 119/242 (49%), Gaps = 15/242 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE--HICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 ++GG C N + VA+Y + CGG L+++ WVLTAAHC + + LG + Sbjct: 1 IIGGDECNINEHRFLVALYTSRSRTLFCGGTLINQEWVLTAAHCDRKNFRIKLGMHSKKV 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 Q R+ + F + + D+ML+RL P + + P +LP Sbjct: 61 PNEDEQTRVPKEKFFC----------LSSKNYTLWDKDIMLIRLDSPVKNSKHIAPFSLP 110 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK---VTDVMLCA 199 + P GS C GWG I+PT PD CV I LL E C Y + T LCA Sbjct: 111 SSPPSVGSVCRIMGWGRISPTEGTYPDVPHCVNINLLEYEMCRAPYPEFELPATSRTLCA 170 Query: 200 GEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 G + GGKDTC+ DSGGPLIC+G QG S+G PC +P PA YT + WI++ + Sbjct: 171 GILEGGKDTCKGDSGGPLICNGQFQGIASWGDDPCAQPHKPAAYTKVFDHLDWIENIIAG 230 Query: 260 NA 261 N Sbjct: 231 NT 232 >2AIQ-A nrPDB Length = 231 Score = 270 bits (691), Expect = 3e-73, Method: Composition-based stats. Identities = 81/237 (34%), Positives = 116/237 (48%), Gaps = 12/237 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N + +A+ Y +CGG L+++ WVLTA HC ++LG + L Sbjct: 1 VIGGDECNINEHRF-LALVYANGSLCGGTLINQEWVLTARHCDRGNMRIYLGMHNLKVLN 59 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 A R + + + + D+ML+RL++P + + P++LP+ Sbjct: 60 KDALRRFPKEKYFCLNTRNDTI----------WDKDIMLIRLNRPVRNSAHIAPLSLPSN 109 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGG 204 P GS C GWG+IT PD C I +L C Y + LCAG + G Sbjct: 110 PPSVGSVCRIMGWGTITSPNATLPDVPHCANINILDYAVCQAAYKG-LAATTLCAGILEG 168 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GKDTC+ DSGGPLIC+G QG S G PC +P P IYT + + WI+ + N Sbjct: 169 GKDTCKGDSGGPLICNGQFQGILSVGGNPCAQPRKPGIYTKVFDYTDWIQSIISGNT 225 >1OP0-A nrPDB Length = 234 Score = 269 bits (688), Expect = 9e-73, Method: Composition-based stats. Identities = 88/238 (36%), Positives = 122/238 (51%), Gaps = 11/238 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N + VA + CGG L++ WV+TAAHC +++ LG + Sbjct: 1 VIGGNECDINEHRFLVAFFNTTGFFCGGTLINPEWVVTAAHCDSTDFQMQLGVHSKKVLN 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P N + ++ D+ML++L KP + + P++LP+ Sbjct: 61 EDEQTRNPKEKFICPNKNNNEVL----------DKDIMLIKLDKPISNSKHIAPLSLPSS 110 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTD-VMLCAGEMG 203 P GS C GWGSITP + PD C I LL + C Y + + + LCAG + Sbjct: 111 PPSVGSVCRIMGWGSITPVKETFPDVPYCANINLLDHAVCQAGYPELLAEYRTLCAGIVQ 170 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GGKDTC DSGGPLIC+G QG SYG PCG+ P IYTN+ + WI+ + N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSYGAHPCGQGPKPGIYTNVFDYTDWIQRNIAGNT 228 >5TJX-A nrPDB Length = 263 Score = 267 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 80/259 (30%), Positives = 125/259 (48%), Gaps = 28/259 (10%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----V 68 +R+VGG PWQV++ + + H+CGG L+ WVLTAAHC+ Sbjct: 8 CTTKTSTRIVGGTESSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ 67 Query: 69 DQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 D + ++ G +L + + H + +S + ++D+ L++L Sbjct: 68 DVWRIYSGILELSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQA 116 Query: 129 PADITDVVKPIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK 186 P + T+ KPI+LP+K + C +GWG + + + LQ V I L+ NE C K Sbjct: 117 PLEYTEFQKPISLPSKGDTSTIYTNCWVTGWGFSKE-KGEIQNILQKVNIPLVTNEECQK 175 Query: 187 VYLQ-KVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPA 241 Y K+T M+CAG GGKD C+ DSGGPL+C L G TS+G C + P Sbjct: 176 RYQDYKITQRMVCAGYKEGGKDACKGDSGGPLVCKHNGMWRLVGITSWGE-GCARREQPG 234 Query: 242 IYTNLIKFNSWIKDTMMKN 260 +YT + ++ WI + + Sbjct: 235 VYTKVAEYMDWILEKTQSS 253 >1X7A-C nrPDB Length = 235 Score = 266 bits (681), Expect = 5e-72, Method: Composition-based stats. Identities = 75/244 (30%), Positives = 115/244 (47%), Gaps = 21/244 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKNKLFQ 82 +VGG N K PWQV + + + CGG +++ WV+TAAHC + V G+ + Sbjct: 1 IVGGENAKPGQFPWQVLLNGKIDAFCGGSIINEKWVVTAAHCIEPGVKITVVAGEYNTEE 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 EP+ Q R V ++ PH +N ++ +S+D+ LL L +P + V PI + Sbjct: 61 TEPTEQRRNVIRAIPHHSYNATV---------NKYSHDIALLELDEPLTLNSYVTPICIA 111 Query: 143 TKEPKP----GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 KE SGWG + R + LQ + + L+ C + + M C Sbjct: 112 DKEYTNIFLKFGSGYVSGWGRVF-NRGRSATILQYLKVPLVDRATCLRSTKFTIYSNMFC 170 Query: 199 AGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 AG GGKD+C+ DSGGP + + L G S+G C G IYT + ++ +WIK Sbjct: 171 AGFHEGGKDSCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAVKGKYGIYTKVSRYVNWIK 229 Query: 255 DTMM 258 + Sbjct: 230 EKTK 233 >3LC3-A nrPDB Length = 235 Score = 266 bits (681), Expect = 6e-72, Method: Composition-based stats. Identities = 70/244 (28%), Positives = 116/244 (47%), Gaps = 21/244 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKNKLFQ 82 VVGG + K PWQV + + + CGG +++ W++TAAHC + V G++ + + Sbjct: 1 VVGGEDAKPGQFPWQVVLNGKVDAFCGGSIVNEKWIVTAAHCVETGVKITVVAGEHNIEE 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 E + Q R V + PH +N ++ +++D+ LL L +P + V PI + Sbjct: 61 TEHTEQKRNVIRIIPHHNYNAAI---------NKYNHDIALLELDEPLVLNSYVTPICIA 111 Query: 143 TKEPKP----GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 KE SGWG + + + LQ + + L+ C + + + M C Sbjct: 112 DKEYTNIFLKFGSGYVSGWGRVFH-KGRSALVLQYLRVPLVDRATCLRSTKFTIYNNMFC 170 Query: 199 AGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 AG GG+D+C+ DSGGP + + L G S+G C G IYT + ++ +WIK Sbjct: 171 AGFHEGGRDSCQGDSGGPHVTEVEGTSFLTGIISWGE-ECAMKGKYGIYTKVSRYVNWIK 229 Query: 255 DTMM 258 + Sbjct: 230 EKTK 233 >6I44-A nrPDB Length = 627 Score = 266 bits (680), Expect = 7e-72, Method: Composition-based stats. Identities = 79/259 (30%), Positives = 122/259 (47%), Gaps = 28/259 (10%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----V 68 +R+VGG PWQV++ + + H+CGG L+ WVLTAAHC+ Sbjct: 372 CTTKTSTRIVGGTQSSWGEWPWQVSLQVKLTAQRHLCGGSLIGHQWVLTAAHCFDGLPLQ 431 Query: 69 DQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 D + ++ G +L + + H + +S + ++D+ L++L Sbjct: 432 DVWRIYSGILQLSDITKDTPFSQIKEIIIHQNYKVS-----------EGNHDIALIKLQA 480 Query: 129 PADITDVVKPIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK 186 P T+ KPI LP+K + C +GWG + + LQ V I L+ NE C K Sbjct: 481 PLQYTEFQKPICLPSKGDTSTIYTNCWVTGWGFSAEA-GEIQNILQKVNIPLVTNEECQK 539 Query: 187 VYLQ-KVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPA 241 Y K+T M+CAG GGKD C+ D+GGPL+C L G TS+G C + P Sbjct: 540 RYQDYKITQRMVCAGYKEGGKDACKGDAGGPLVCKHNGMWRLVGITSWGE-GCARREQPG 598 Query: 242 IYTNLIKFNSWIKDTMMKN 260 +YT + ++ WI + + Sbjct: 599 VYTKVAEYMDWILEKTQSS 617 >1BQY-A nrPDB Length = 234 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 81/237 (34%), Positives = 119/237 (50%), Gaps = 11/237 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V GG C N V ++ +CGG L++++WV+TAAHC + +++ G + Sbjct: 1 VFGGDECNINEHRSLVVLFNSNGFLCGGTLINQDWVVTAAHCDSNNFQLLFGVHSKKILN 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P + D+ML++L ++ + P++LP+ Sbjct: 61 EDEQTRDPKEKFFCPNRKKD----------DEVDKDIMLIKLDSSVSNSEHIAPLSLPSS 110 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTDVMLCAGEMG 203 P GS C GWG PT+ PD C I +L + C Y + V + LCAG + Sbjct: 111 PPSVGSVCRIMGWGKTIPTKEIYPDVPHCANINILDHAVCRTAYSWRQVANTTLCAGILQ 170 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 GG+DTC DSGGPLIC+GI QG S+G PCG+PG P +YT + + WIK + N Sbjct: 171 GGRDTCHFDSGGPLICNGIFQGIVSWGGHPCGQPGEPGVYTKVFDYLDWIKSIIAGN 227 >3S69-A nrPDB Length = 234 Score = 265 bits (677), Expect = 2e-71, Method: Composition-based stats. Identities = 84/238 (35%), Positives = 119/238 (50%), Gaps = 11/238 (4%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 V+GG C N VA + C G L++ WVLTAAHC +++ LG + Sbjct: 1 VIGGDECNINEHRSLVAFFNSTGFFCSGTLINEEWVLTAAHCDNTNFQMKLGVHSKKVLN 60 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTK 144 Q R + F P ++ D+ML++L ++ + P++LP+ Sbjct: 61 EDEQTRNPKEKFICPNKKNDEVL----------DKDIMLIKLDSRVSNSEHIVPLSLPSS 110 Query: 145 EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTD-VMLCAGEMG 203 P GS C GWGSITP + PD C +I LL + C Y + +T+ LCAG + Sbjct: 111 PPSVGSVCHIMGWGSITPIKVTYPDVPYCAYINLLDDAVCQAGYPELLTEYRTLCAGILE 170 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 GGKDTC DSGGPLIC+G QG S+G PCG+ P +YT + +N WI+ + N Sbjct: 171 GGKDTCGGDSGGPLICNGQFQGIVSFGAHPCGQGLKPGVYTKVFDYNHWIQSIIAGNT 228 >2BDH-A nrPDB Length = 223 Score = 263 bits (673), Expect = 5e-71, Method: Composition-based stats. Identities = 95/236 (40%), Positives = 137/236 (58%), Gaps = 14/236 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF-QE 83 ++ G +C +SQPWQ A+ + E C GVL+ WVL+AAHC+ + Y + LG + L + Sbjct: 1 IINGEDCSPHSQPWQAALVMENELFCSGVLVHPQWVLSAAHCFQNSYTIGLGLHSLEADQ 60 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 EP +Q S S HP +N LL +NDLML++L + +D ++ I++ + Sbjct: 61 EPGSQMVEASLSVRHPEYNRPLL-----------ANDLMLIKLDESVSESDTIRSISIAS 109 Query: 144 KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMG 203 + P G+ CL SGWG + + P LQCV ++++ E C+K+Y M CAG Sbjct: 110 QCPTAGNSCLVSGWGLLA--NGRMPTVLQCVNVSVVSEEVCSKLYDPLYHPSMFCAGGGQ 167 Query: 204 GGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 KD+C DSGGPLIC+G LQG S+G PCG+ GVP +YTNL KF WI+ T+ Sbjct: 168 DQKDSCNGDSGGPLICNGYLQGLVSFGKAPCGQVGVPGVYTNLCKFTEWIEKTVQA 223 >5LPF-A nrPDB Length = 234 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 88/233 (37%), Positives = 128/233 (54%), Gaps = 5/233 (2%) Query: 28 GFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSA 87 G C + SQPWQV+++ C GVL+D++WVLTAAHC +G + L + Sbjct: 7 GSPCARGSQPWQVSLFNGLSFHCAGVLVDQSWVLTAAHCGNKPLWARVGDDHLLLLQ-GE 65 Query: 88 QHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK 147 Q R ++S HP ++ I P +DLMLL+L++P + V+ + LP + + Sbjct: 66 QLRRTTRSVVHPKYHQGS---GPILPRRTDEHDLMLLKLARPVVLGPRVRALQLPYRCAQ 122 Query: 148 PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKD 207 PG +C +GWG+ R + L C IT+L + C Y VT+ M+CAG + G+D Sbjct: 123 PGDQCQVAGWGTTAARRVKYNKGLTCSSITILSPKECEVFYPGVVTNNMICAG-LDRGQD 181 Query: 208 TCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 C+ DSGGPL+CD LQG S+G PCG PA+YT + K+ SWI + N Sbjct: 182 PCQSDSGGPLVCDETLQGILSWGVYPCGSAQHPAVYTQICKYMSWINKVIRSN 234 >5UGG-A nrPDB Length = 251 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 90/268 (33%), Positives = 125/268 (46%), Gaps = 35/268 (13%) Query: 8 LALSLGGIDAAPP-LQSRVVGGFNCKKNSQPWQVAVYYQ-KEHICGGVLLDRNWVLTAAH 65 + G P RVVGG +S PWQV++ + H CGG L+ WVLTAAH Sbjct: 4 PSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAH 63 Query: 66 CY-----VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSND 120 C Y+V LG ++ EP Q VS+ F P D Sbjct: 64 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP-----------------TRKD 106 Query: 121 LMLLRLSKPADITDVVKPIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITL 178 + LL+LS PA ITD V P LP+ ++C +GWG T L+ + + Sbjct: 107 IALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPV 164 Query: 179 LPNENCAK--VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPV 232 + N+ C + +V LCAG + GG D+C+ DSGGPL+C ILQG TS+G + Sbjct: 165 IENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-L 223 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 C +P P +Y + +F +WI+ M N Sbjct: 224 GCARPNKPGVYVRVSRFVTWIEGVMRNN 251 >4DUR-A nrPDB Length = 791 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 90/268 (33%), Positives = 125/268 (46%), Gaps = 35/268 (13%) Query: 8 LALSLGGIDAAPP-LQSRVVGGFNCKKNSQPWQVAVYYQ-KEHICGGVLLDRNWVLTAAH 65 + G P RVVGG +S PWQV++ + H CGG L+ WVLTAAH Sbjct: 544 PSFDCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFGMHFCGGTLISPEWVLTAAH 603 Query: 66 CY-----VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSND 120 C Y+V LG ++ EP Q VS+ F P D Sbjct: 604 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEP-----------------TRKD 646 Query: 121 LMLLRLSKPADITDVVKPIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITL 178 + LL+LS PA ITD V P LP+ ++C +GWG T L+ + + Sbjct: 647 IALLKLSSPAVITDKVIPACLPSPNYVVADRTECFITGWGETQGTFG--AGLLKEAQLPV 704 Query: 179 LPNENCAKV--YLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPV 232 + N+ C + +V LCAG + GG D+C+ DSGGPL+C ILQG TS+G + Sbjct: 705 IENKVCNRYEFLNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCFEKDKYILQGVTSWG-L 763 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 C +P P +Y + +F +WI+ M N Sbjct: 764 GCARPNKPGVYVRVSRFVTWIEGVMRNN 791 >3T2N-A nrPDB Length = 372 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 79/256 (30%), Positives = 118/256 (46%), Gaps = 27/256 (10%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV------DQYEVWLGK 77 R+VGG + PWQV++ Y H+CGG LL +WVLTAAHC+ ++ V+ G Sbjct: 117 RIVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA 176 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 + Q P V H G+ + P + SND+ L+ LS P +T+ ++ Sbjct: 177 --VAQASPHGLQLGVQAVVYHGGY-----LPFRDPNSEENSNDIALVHLSSPLPLTEYIQ 229 Query: 138 PIALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KVYLQKVT 193 P+ LP G C +GWG+ T Q+ LQ + ++ N+ C Y ++ Sbjct: 230 PVCLPAAGQALVDGKICTVTGWGN-TQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIK 288 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLICD--------GILQGTTSYGPVPCGKPGVPAIYTN 245 M CAG GG D C+ DSGGP +C+ L G S+G C P +YT Sbjct: 289 PKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTK 347 Query: 246 LIKFNSWIKDTMMKNA 261 + F WI + ++ Sbjct: 348 VSDFREWIFQAIKTHS 363 >3K65-B nrPDB Length = 308 Score = 260 bits (664), Expect = 5e-70, Method: Composition-based stats. Identities = 70/269 (26%), Positives = 117/269 (43%), Gaps = 43/269 (15%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------V 68 + R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC Sbjct: 46 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 105 Query: 69 DQYEVWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 106 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 155 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT-----RWQKPDDLQCVFIT 177 KP +D + P+ LP +E + G K +GWG++ T +P LQ V + Sbjct: 156 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 215 Query: 178 LLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTS 228 ++ C ++TD M CAG G D C D+GGP + G S Sbjct: 216 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDAGGPFVMKSPFNNRWYQMGIVS 275 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 +G C + G YT++ + WI+ + Sbjct: 276 WGE-GCDRDGKYGFYTHVFRLKKWIQKVI 303 >3NXP-A nrPDB Length = 424 Score = 260 bits (664), Expect = 6e-70, Method: Composition-based stats. Identities = 71/269 (26%), Positives = 117/269 (43%), Gaps = 43/269 (15%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------V 68 + R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC Sbjct: 162 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 221 Query: 69 DQYEVWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 222 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 271 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT-----RWQKPDDLQCVFIT 177 KP +D + P+ LP +E + G K +GWG++ T +P LQ V + Sbjct: 272 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 331 Query: 178 LLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTS 228 ++ C ++TD M CAG G D C DSGGP + G S Sbjct: 332 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 391 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 +G C + G YT++ + WI+ + Sbjct: 392 WGE-GCDRDGKYGFYTHVFRLKKWIQKVI 419 >2F83-A nrPDB Length = 625 Score = 259 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 80/253 (31%), Positives = 120/253 (47%), Gaps = 28/253 (11%) Query: 16 DAAPPLQSRVVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCYVDQ-- 70 + ++ R+VGG + PWQV ++ + H+CGG ++ W+LTAAHC+ Sbjct: 379 ECTTKIKPRIVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVES 438 Query: 71 ---YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 V+ G + + V + H + M A+ D+ LL+L Sbjct: 439 PKILRVYSGILNQSEIKEDTSFFGVQEIIIHDQYKM-----------AESGYDIALLKLE 487 Query: 128 KPADITDVVKPIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 + TD +PI LP+K + + C +GWG R + + LQ I L+ NE C Sbjct: 488 TTVNYTDSQRPICLPSKGDRNVIYTDCWVTGWGYRK-LRDKIQNTLQKAKIPLVTNEECQ 546 Query: 186 KVYLQ-KVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVP 240 K Y K+T M+CAG GGKD C+ DSGGPL C L G TS+G C + P Sbjct: 547 KRYRGHKITHKMICAGYREGGKDACKGDSGGPLSCKHNEVWHLVGITSWGE-GCAQRERP 605 Query: 241 AIYTNLIKFNSWI 253 +YTN++++ WI Sbjct: 606 GVYTNVVEYVDWI 618 >5GVT-A nrPDB Length = 250 Score = 259 bits (663), Expect = 7e-70, Method: Composition-based stats. Identities = 78/251 (31%), Positives = 122/251 (48%), Gaps = 28/251 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCY-----VDQYEVWLG 76 +VGG N PWQV++ + + H+CGG ++ R WVLTAAHC+ D + ++ G Sbjct: 1 IVGGTNASLGEWPWQVSLQVKLVSQTHLCGGSIIGRQWVLTAAHCFDGIPYPDVWRIYGG 60 Query: 77 KNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVV 136 L + + + H + +S + + D+ L++L P + T+ Sbjct: 61 ILSLSEITKETPSSRIKELIIHQEYKVS-----------EGNYDIALIKLQTPLNYTEFQ 109 Query: 137 KPIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTD 194 KPI+LP+K + C +GWG + + + LQ I L+PNE C K Y V + Sbjct: 110 KPISLPSKADTNTIYTNCWVTGWGYTKE-QGETQNILQKATIPLVPNEECQKKYRDYVIN 168 Query: 195 V-MLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 M+CAG GG D C+ DSGGPL+C L G TS+G C + P +YT + ++ Sbjct: 169 KQMICAGYKEGGTDACKGDSGGPLVCKHSGRWQLVGITSWGE-GCARKDQPGVYTKVSEY 227 Query: 250 NSWIKDTMMKN 260 WI + + Sbjct: 228 MDWILEKTQSS 238 >1MKW-K nrPDB Length = 308 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 74/269 (27%), Positives = 118/269 (43%), Gaps = 43/269 (15%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------V 68 ++ R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC V Sbjct: 46 IEGRIVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTV 105 Query: 69 DQYEVWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 D V +GK+ + E + ++ K + HP +N + D+ LL+L Sbjct: 106 DDLLVRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLK 155 Query: 128 KPADITDVVKPIALPTKEPKP-----GSKCLASGWGS-----ITPTRWQKPDDLQCVFIT 177 +P +++D + P+ LP K+ G K +GWG+ T +P LQ V + Sbjct: 156 RPIELSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLP 215 Query: 178 LLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTS 228 L+ C ++TD M CAG G D C DSGGP + G S Sbjct: 216 LVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVS 275 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 +G C + G YT++ + WI+ + Sbjct: 276 WGE-GCDRDGKYGFYTHVFRLKKWIQKVI 303 >4NZQ-A nrPDB Length = 557 Score = 258 bits (659), Expect = 2e-69, Method: Composition-based stats. Identities = 71/269 (26%), Positives = 117/269 (43%), Gaps = 43/269 (15%) Query: 21 LQSRVVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------V 68 + R+V G + + PWQV ++ + +E +CG L+ WVLTAAHC Sbjct: 295 IDGRIVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTE 354 Query: 69 DQYEVWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 355 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 404 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT-----RWQKPDDLQCVFIT 177 KP +D + P+ LP +E + G K +GWG++ T +P LQ V + Sbjct: 405 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 464 Query: 178 LLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTS 228 ++ C ++TD M CAG G D C DSGGP + G S Sbjct: 465 IVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 524 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 +G C + G YT++ + WI+ + Sbjct: 525 WGE-GCDRDGKYGFYTHVFRLKKWIQKVI 552 >3S9B-A nrPDB Length = 234 Score = 257 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 81/239 (33%), Positives = 117/239 (48%), Gaps = 15/239 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHI--CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 VVGG C N P+ VA+Y C G L++R WVLTAAHC + LG + Sbjct: 1 VVGGDECNINEHPFLVALYTSASSTIHCAGALINREWVLTAAHCDRRNIRIKLGMHSKNI 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 Q R+ + D+ML+RL +P + + P++LP Sbjct: 61 RNEDEQIRVPRGKYFCLN----------TKFPNGLDKDIMLIRLRRPVTYSTHIAPVSLP 110 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV-MLCAGE 201 ++ GS+C GWG I+ T PD C I ++ ++ C +Y D LCAG Sbjct: 111 SRSRGVGSRCRIMGWGKISTT--TYPDVPHCTNIFIVKHKWCEPLYPWVPADSRTLCAGI 168 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 + GG+DTC DSGGPLIC+G + G + G PCG+ PA+YT + +N+WI+ + N Sbjct: 169 LKGGRDTCHGDSGGPLICNGEMHGIVAGGSEPCGQHLKPAVYTKVFDYNNWIQSIIAGN 227 >2CGA-A nrPDB Length = 245 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 83/259 (32%), Positives = 120/259 (46%), Gaps = 24/259 (9%) Query: 12 LGGIDAAPPLQ--SRVVGGFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYV 68 G P L SR+V G S PWQV++ + H CGG L++ NWV+TAAHC V Sbjct: 1 CGVPAIQPVLSGLSRIVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGV 60 Query: 69 DQYEVWL-GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 +V + G+ Q ++K F + +N +ND+ LL+LS Sbjct: 61 TTSDVVVAGEFDQGSSSEKIQKLKIAKVFKNSKYNS-----------LTINNDITLLKLS 109 Query: 128 KPADITDVVKPIALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 A + V + LP+ + G+ C+ +GWG T PD LQ + LL N NC Sbjct: 110 TAASFSQTVSAVCLPSASDDFAAGTTCVTTGWGLTRYTNANTPDRLQQASLPLLSNTNCK 169 Query: 186 KVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPA 241 K + K+ D M+CAG G +C DSGGPL+C L G S+G C P Sbjct: 170 KYWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAWTLVGIVSWGSSTCSTS-TPG 226 Query: 242 IYTNLIKFNSWIKDTMMKN 260 +Y + +W++ T+ N Sbjct: 227 VYARVTALVNWVQQTLAAN 245 >3E0N-B nrPDB Length = 271 Score = 257 bits (656), Expect = 4e-69, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 121/255 (47%), Gaps = 32/255 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ-----YEVWLGKNK 79 + GG + PWQV++ Y+ H+CGG L+ WVL+AAHC+ + YEV LG ++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L A+ + PHP + D+ LL+LS+P + ++PI Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY-----------LQEGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 ALPTKE--PKPGSKCLASGWGSITPT-RWQKPDDLQCVFITLLPNENCAKVY-------- 188 +LP + G C +GWG + P+ P LQ + + L+ E C +Y Sbjct: 110 SLPAAQASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNSLYNIDAKPEE 169 Query: 189 LQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYT 244 V + M+CAG + GGKD C+ DSGGPL C L G S+G CG P +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYT 228 Query: 245 NLIKFNSWIKDTMMK 259 + SWI+ + + Sbjct: 229 LASSYASWIQSKVTE 243 >1IAU-A nrPDB Length = 227 Score = 256 bits (655), Expect = 5e-69, Method: Composition-based stats. Identities = 80/241 (33%), Positives = 121/241 (50%), Gaps = 21/241 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHI---CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG K +S+P+ + + CGG L+ ++VLTAAHC+ V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAYLMIWDQKSLKRCGGFLIRDDFVLTAAHCWGSSINVTLGAHNIK 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 ++EP+ Q V + PHP +N +FSND+MLL+L + A T V+P+ L Sbjct: 61 EQEPTQQFIPVKRPIPHPAYNPK-----------NFSNDIMLLQLERKAKRTRAVQPLRL 109 Query: 142 PTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV-TDVMLC 198 P+ + KPG C +GWG P + LQ V +T+ + C + + LC Sbjct: 110 PSNKAQVKPGQTCSVAGWGQTAPL-GKHSHTLQEVKMTVQEDRKCESDLRHYYDSTIELC 168 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G+ K + + DSGGPL+C+ + QG SYG G P P T + F WIK TM Sbjct: 169 VGDPEIKKTSFKGDSGGPLVCNKVAQGIVSYGRNN-GMP--PRACTKVSSFVHWIKKTMK 225 Query: 259 K 259 + Sbjct: 226 R 226 >3DFJ-A nrPDB Length = 263 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 81/255 (31%), Positives = 120/255 (47%), Gaps = 32/255 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ-----YEVWLGKNK 79 + GG + PWQV++ Y+ H+CGG L+ WVL+AAHC+ + YEV LG ++ Sbjct: 1 ITGGSSAVAGQWPWQVSITYEGVHVCGGSLVSEQWVLSAAHCFPSEHHKEAYEVKLGAHQ 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L A+ + PHP + D+ LL+LS+P + ++PI Sbjct: 61 LDSYSEDAKVSTLKDIIPHPSY-----------LQEGSQGDIALLQLSRPITFSRYIRPI 109 Query: 140 ALPTKE--PKPGSKCLASGWGSITPT-RWQKPDDLQCVFITLLPNENCAKVY-------- 188 +LP G C +GWG + P+ P LQ + + L+ E C +Y Sbjct: 110 SLPAANASFPNGLHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRETCNALYNIDAKPEE 169 Query: 189 LQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYT 244 V + M+CAG + GGKD C+ DSGGPL C L G S+G CG P +YT Sbjct: 170 PHFVQEDMVCAGYVEGGKDACQGDSGGPLSCPVEGLWYLTGIVSWGDA-CGARNRPGVYT 228 Query: 245 NLIKFNSWIKDTMMK 259 + SWI+ + + Sbjct: 229 LASSYASWIQSKVTE 243 >1FDP-A nrPDB Length = 235 Score = 255 bits (653), Expect = 9e-69, Method: Composition-based stats. Identities = 81/251 (32%), Positives = 131/251 (52%), Gaps = 26/251 (10%) Query: 18 APPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD----QYEV 73 A P + R++GG + +++P+ +V H+CGGVL+ WVL+AAHC D + +V Sbjct: 1 AAPPRGRILGGREAEAHARPYMASVQLNGAHLCGGVLVAEQWVLSAAHCLEDAADGKVQV 60 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADIT 133 LG + L Q EPS + V ++ PHP +DL+LL+LS+ A + Sbjct: 61 LLGAHSLSQPEPSKRLYDVLRAVPHPD-----------SQPDTIDHDLLLLQLSEKATLG 109 Query: 134 DVVKPIALP----TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--V 187 V+P LP ++ PG+ C +GWG + ++PD LQ V + +L C + Sbjct: 110 PAVRP--LPWQRVDRDVAPGTLCDVAGWGIVNHA-GRRPDSLQHVLLPVLDRATCNRRTH 166 Query: 188 YLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLI 247 + +T+ ++CA +D+C+ DSGGPL+C G+L+G + G CG P IYT + Sbjct: 167 HDGAITERLMCA--ESNRRDSCKGDSGGPLVCGGVLEGVVTSGSRVCGNRKKPGIYTRVA 224 Query: 248 KFNSWIKDTMM 258 + +WI + Sbjct: 225 SYAAWIDSVLA 235 >1NN6-A nrPDB Length = 228 Score = 255 bits (653), Expect = 1e-68, Method: Composition-based stats. Identities = 79/244 (32%), Positives = 117/244 (47%), Gaps = 22/244 (9%) Query: 23 SRVVGGFNCKKNSQPWQVAV----YYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKN 78 ++GG CK +S+P+ + CGG L+ RN+VLTAAHC V LG + Sbjct: 1 GEIIGGTECKPHSRPYMAYLEIVTSNGPSKFCGGFLIRRNFVLTAAHCAGRSITVTLGAH 60 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 + +EE + Q V K F HP +N S L +D+MLL+L + A +T V Sbjct: 61 NITEEEDTWQKLEVIKQFRHPKYNTSTL-----------HHDIMLLKLKEKASLTLAVGT 109 Query: 139 IALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 + P++ PG C +GWG + D LQ V + L+ + C+ + ++ Sbjct: 110 LPFPSQFNFVPPGRMCRVAGWGRTGVLK-PGSDTLQEVKLRLMDPQACS-HFRDFDHNLQ 167 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 LC G K + DSGGPL+C G+ QG SYG KP PA++T + + WI Sbjct: 168 LCVGNPRKTKSAFKGDSGGPLLCAGVAQGIVSYGRSD-AKP--PAVFTRISHYRPWINQI 224 Query: 257 MMKN 260 + N Sbjct: 225 LQAN 228 >1P57-B nrPDB Length = 255 Score = 255 bits (652), Expect = 1e-68, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 117/255 (45%), Gaps = 27/255 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV------DQYEVWLGKN 78 +VGG + PWQV++ Y H+CGG LL +WVLTAAHC+ ++ V+ G Sbjct: 1 IVGGRDTSLGRWPWQVSLRYDGAHLCGGSLLSGDWVLTAAHCFPERNRVLSRWRVFAGA- 59 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 + Q P V H G+ + P + SND+ L+ LS P +T+ ++P Sbjct: 60 -VAQASPHGLQLGVQAVVYHGGY-----LPFRDPNSEENSNDIALVHLSSPLPLTEYIQP 113 Query: 139 IALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KVYLQKVTD 194 + LP G C +GWG+ T Q+ LQ + ++ N+ C Y ++ Sbjct: 114 VCLPAAGQALVDGKICTVTGWGN-TQYYGQQAGVLQEARVPIISNDVCNGADFYGNQIKP 172 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICD--------GILQGTTSYGPVPCGKPGVPAIYTNL 246 M CAG GG D C+ DSGGP +C+ L G S+G C P +YT + Sbjct: 173 KMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWRLCGIVSWGT-GCALAQKPGVYTKV 231 Query: 247 IKFNSWIKDTMMKNA 261 F WI + ++ Sbjct: 232 SDFREWIFQAIKTHS 246 >1BRU-P nrPDB Length = 241 Score = 255 bits (651), Expect = 2e-68, Method: Composition-based stats. Identities = 83/252 (32%), Positives = 119/252 (47%), Gaps = 27/252 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKN 78 VVGG + + NS PWQV++ Y H CGG L+D++WVLTAAHC Y V LG++ Sbjct: 1 VVGGEDARPNSWPWQVSLQYDSSGQWRHTCGGTLVDQSWVLTAAHCISSSRTYRVVLGRH 60 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 L EP + VSK H +N + L ND+ LL+L+ P +TD ++ Sbjct: 61 SLSTNEPGSLAVKVSKLVVHQDWNSNQLSN---------GNDIALLKLASPVSLTDKIQL 111 Query: 139 IALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQKVTD 194 LP C +GWG + T PD LQ + ++ C+K + V Sbjct: 112 GCLPAAGTILPNNYVCYVTGWGRL-QTNGASPDILQQGQLLVVDYATCSKPGWWGSTVKT 170 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSYG-PVPCGKPGVPAIYTNLIK 248 M+CAG G +C DSGGPL C G + G S+G + C P+++T + Sbjct: 171 NMICAGG-DGIISSCNGDSGGPLNCQGANGQWQVHGIVSFGSSLGCNYYHKPSVFTRVSN 229 Query: 249 FNSWIKDTMMKN 260 + WI + N Sbjct: 230 YIDWINSVIANN 241 >3W94-A nrPDB Length = 235 Score = 254 bits (650), Expect = 2e-68, Method: Composition-based stats. Identities = 78/246 (31%), Positives = 119/246 (48%), Gaps = 27/246 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------YEVWLGKN 78 VVGG N +K + PW V+++++ H CG L+ R+W+LTAAHC + + LG + Sbjct: 1 VVGGVNAEKGAWPWMVSLHWRGRHGCGASLIGRDWLLTAAHCVYGKNTHLQYWSAVLGLH 60 Query: 79 KLFQ-EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 Q R V + + +N D+ ++ L +P + T+ V Sbjct: 61 AQSSMNSQEVQIRQVDRIIINKNYNRRTKEA-----------DIAMMHLQQPVNFTEWVL 109 Query: 138 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVTD 194 P+ L +++ G +C +GWG PD LQ + L+ + C ++ + T Sbjct: 110 PVCLASEDQHFPAGRRCFIAGWGRDAE-GGSLPDILQEAEVPLVDQDECQRLLPEYTFTS 168 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKFN 250 MLCAG GG D+C+ DSGGPL+C L G TS+G V CG+P P Y + F Sbjct: 169 SMLCAGYPEGGVDSCQGDSGGPLMCLEDARWTLIGVTSFG-VGCGRPERPGAYARVSAFT 227 Query: 251 SWIKDT 256 SWI +T Sbjct: 228 SWIAET 233 >4DGJ-A nrPDB Length = 235 Score = 253 bits (646), Expect = 6e-68, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 119/245 (48%), Gaps = 27/245 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY------VDQYEVWLGKN 78 +VGG + K+ + PW V +YY +CG L+ +W+++AAHC ++ LG + Sbjct: 1 IVGGSDAKEGAWPWVVGLYYDDRLLCGASLVSSDWLVSAAHCVYGRNLEPSKWTAILGLH 60 Query: 79 KLFQ-EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 P RL+ + +P +N ND+ ++ L + TD ++ Sbjct: 61 MKSNLTSPQTVPRLIDEIVINPHYNRRRK-----------DNDIAMMHLEFKVNYTDYIQ 109 Query: 138 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTD 194 PI+LP + PG C +GWG++ + D LQ + LL NE C + + +T+ Sbjct: 110 PISLPEENQVFPPGRNCSIAGWGTVV-YQGTTADILQEADVPLLSNERCQQQMPEYNITE 168 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFN 250 M+CAG GG D+C+ DSGGPL+C L G TS+G C P P +Y + +F Sbjct: 169 NMICAGYEEGGIDSCQGDSGGPLMCQENNRWFLAGVTSFG-YECALPNRPGVYARVSRFT 227 Query: 251 SWIKD 255 WI+ Sbjct: 228 EWIQS 232 >2F91-A nrPDB Length = 237 Score = 252 bits (644), Expect = 1e-67, Method: Composition-based stats. Identities = 79/246 (32%), Positives = 112/246 (45%), Gaps = 29/246 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ----KEHICGGVLLDRNWVLTAAHCYVDQ-------YEV 73 +VGG + P+Q++ H CG + + N+ +TA HC ++ Sbjct: 1 IVGGTDATLGEFPYQLSFQETFIGFSFHFCGASIYNENYAITAGHCVYGDDYENPSGLQI 60 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADIT 133 G+ + E S Q VSK H F+ +LL ND+ LL+LS Sbjct: 61 VAGELDMSVNEGSEQIITVSKIILHENFDYNLL-----------DNDISLLKLSGSLTFN 109 Query: 134 DVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-QKV 192 D V PIALP + + +GWG T PD LQ V + L+ +E+C Y ++ Sbjct: 110 DNVAPIALPEQGHTATGDVIVTGWG-TTSEGGNTPDVLQKVTVPLVSDEDCRADYGADEI 168 Query: 193 TDVMLCAGEMGGGKDTCRDDSGGPLICDGI----LQGTTSYGPVPCGKPGVPAIYTNLIK 248 D M+CAG GGKD+C+ DSGGPL L G S+G C +PG P +YT + Sbjct: 169 LDSMICAGVPEGGKDSCQGDSGGPLAASDTGSTYLAGIVSWG-YGCARPGYPGVYTEVSY 227 Query: 249 FNSWIK 254 WIK Sbjct: 228 HVDWIK 233 >2OCV-B nrPDB Length = 259 Score = 252 bits (643), Expect = 2e-67, Method: Composition-based stats. Identities = 71/265 (26%), Positives = 116/265 (43%), Gaps = 43/265 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G++ +K PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 1 IVEGWDAEKGIAPWQVMLFRKSPQELLCGASLISDRWVLTAAHCILYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + + ++ K + HP +N + D+ LL+L KP Sbjct: 61 VRIGKHSRTRYERNVEKISMLEKIYVHPRYNWR----------ENLDRDIALLKLKKPVP 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGS-----ITPTRWQKPDDLQCVFITLLPN 181 +D + P+ LP K+ + G K +GWG+ T +P LQ V + ++ Sbjct: 111 FSDYIHPVCLPDKQTVTSLLRAGYKGRVTGWGNLRETWTTNINEIQPSVLQVVNLPIVER 170 Query: 182 ENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTSYGPV 232 C ++TD M CAG D C DSGGP + G S+G Sbjct: 171 PVCKASTRIRITDNMFCAGFKVNDTKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSWGE- 229 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTM 257 C + G YT++ + +WI+ + Sbjct: 230 GCDRKGKYGFYTHVFRLKAWIQKVI 254 >1EKB-B nrPDB Length = 235 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 75/245 (30%), Positives = 125/245 (51%), Gaps = 27/245 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY------VDQYEVWLGKN 78 +VGG + ++ + PW VA+Y+ + +CG L+ R+W+++AAHC +++ LG + Sbjct: 1 IVGGSDSREGAWPWVVALYFDDQQVCGASLVSRDWLVSAAHCVYGRNMEPSKWKAVLGLH 60 Query: 79 KLFQ-EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 P + RL+ + +P +N +ND+ ++ L + TD ++ Sbjct: 61 MASNLTSPQIETRLIDQIVINPHYNKRRK-----------NNDIAMMHLEMKVNYTDYIQ 109 Query: 138 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTD 194 PI LP + PG C +GWG++ + D LQ + LL NE C + + +T+ Sbjct: 110 PICLPEENQVFPPGRICSIAGWGALI-YQGSTADVLQEADVPLLSNEKCQQQMPEYNITE 168 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFN 250 M+CAG GG D+C+ DSGGPL+C +L G TS+G C P P +Y + +F Sbjct: 169 NMVCAGYEAGGVDSCQGDSGGPLMCQENNRWLLAGVTSFG-YQCALPNRPGVYARVPRFT 227 Query: 251 SWIKD 255 WI+ Sbjct: 228 EWIQS 232 >3TK9-A nrPDB Length = 226 Score = 251 bits (641), Expect = 2e-67, Method: Composition-based stats. Identities = 74/241 (30%), Positives = 122/241 (50%), Gaps = 22/241 (9%) Query: 25 VVGGFNCKKNSQPWQVA---VYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG K +S+P+ + + CGG+L+ +++VLTAAHC V LG + + Sbjct: 1 IIGGHEAKPHSRPYMAFVQFLQEKSRKRCGGILVRKDFVLTAAHCQGSSINVTLGAHNIK 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 ++E + Q V + PHP +N +FSN++MLL+L + A T V+P+ L Sbjct: 61 EQERTQQFIPVKRPIPHPAYNPK-----------NFSNNIMLLQLERKAKWTTAVRPLRL 109 Query: 142 PT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM-LC 198 P+ + KPG C +GWG ++ + LQ V +T+ + C +++ + +C Sbjct: 110 PSSKAQVKPGQLCSVAGWGYVSMS--TLATTLQEVLLTVQKDCQCERLFHGNYSRATEIC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G+ + + DSGGPL+C + QG SYG K P +Y + F WIK TM Sbjct: 168 VGDPKKTQTGFKGDSGGPLVCKDVAQGILSYGNK---KGTPPGVYIKVSHFLPWIKRTMK 224 Query: 259 K 259 + Sbjct: 225 R 225 >1KIG-H nrPDB Length = 241 Score = 250 bits (640), Expect = 4e-67, Method: Composition-based stats. Identities = 65/249 (26%), Positives = 101/249 (40%), Gaps = 25/249 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEH-ICGGVLLDRNWVLTAAHCYV--DQYEVWLGKNKLF 81 +VGG +C + PWQ + ++ CGG +L+ +VLTAAHC ++ V +G Sbjct: 1 IVGGRDCAEGECPWQALLVNEENEGFCGGTILNEFYVLTAAHCLHQAKRFTVRVGDRNTE 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 QEE + V + H F + D+ +LRL P V P L Sbjct: 61 QEEGNEMAHEVEMTVKHSRF-----------VKETYDFDIAVLRLKTPIRFRRNVAPACL 109 Query: 142 PTKEPKPGS-----KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 P K+ + + SG+G + + L+ + + + C +T M Sbjct: 110 PEKDWAEATLMTQKTGIVSGFGRT-HEKGRLSSTLKMLEVPYVDRSTCKLSSSFTITPNM 168 Query: 197 LCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSW 252 CAG +D C+ DSGGP + + G S+G C + G +YT + F W Sbjct: 169 FCAGYDTQPEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKFGVYTKVSNFLKW 227 Query: 253 IKDTMMKNA 261 I M A Sbjct: 228 IDKIMKARA 236 >1ETT-H nrPDB Length = 259 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 73/265 (27%), Positives = 115/265 (43%), Gaps = 43/265 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC VD Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 VWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + ++ K + HP +N + D+ LL+L +P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKPIALPTKEPKP-----GSKCLASGWGS-----ITPTRWQKPDDLQCVFITLLPN 181 ++D + P+ LP K+ G K +GWG+ T +P LQ V + L+ Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRETWTTSVAEVQPSVLQVVNLPLVER 170 Query: 182 ENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTSYGPV 232 C ++TD M CAG G D C DSGGP + G S+G Sbjct: 171 PVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPYNNRWYQMGIVSWGE- 229 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTM 257 C + G YT++ + WI+ + Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >3G01-A nrPDB Length = 227 Score = 249 bits (636), Expect = 9e-67, Method: Composition-based stats. Identities = 78/241 (32%), Positives = 117/241 (48%), Gaps = 22/241 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYY----QKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG +S+P+ + K+ CGG L+ +VLTAAHC V LG + + Sbjct: 1 IIGGNEISPHSRPYMAYYEFLKVGGKKMFCGGFLVRDKFVLTAAHCKGRSMTVTLGAHNI 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 +E + Q V+K+ PHP +N D SND+MLL+L + A T V+P+ Sbjct: 61 KAKEETQQIIPVAKAIPHPDYNPD-----------DRSNDIMLLKLVRNAKRTRAVRPLN 109 Query: 141 LPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTD-VML 197 LP + KPG +C +GWG +TP + P L V +T+ ++ C + + Sbjct: 110 LPRRNAHVKPGDECYVAGWGKVTP-DGEFPKTLHEVKLTVQKDQVCESQFQSSYNRANEI 168 Query: 198 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 C G+ + R DSGGPL+C G SYG P ++T ++ F SWIK TM Sbjct: 169 CVGDSKIKGASFRGDSGGPLVCKRAAAGIVSYGQT---DGSAPQVFTRVLSFVSWIKKTM 225 Query: 258 M 258 Sbjct: 226 K 226 >1VR1-H nrPDB Length = 261 Score = 248 bits (633), Expect = 2e-66, Method: Composition-based stats. Identities = 68/269 (25%), Positives = 112/269 (41%), Gaps = 47/269 (17%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE------HICGGVLLDRNWVLTAAHCY----------V 68 +V G + + PWQV ++ + +CG L+ WVLTAAHC Sbjct: 1 IVEGSDAEIGMSPWQVMLFAKHRRSPGERFLCGASLISDRWVLTAAHCLLYPPWDKNFTE 60 Query: 69 DQYEVWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +GK+ + E + + ++ K + HP +N + D+ L++L Sbjct: 61 NDLLVRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLK 110 Query: 128 KPADITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT-----RWQKPDDLQCVFIT 177 KP +D + P+ LP +E + G K +GWG++ T +P LQ V + Sbjct: 111 KPVAFSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLP 170 Query: 178 LLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTS 228 ++ C ++TD M CA G D C DSGGP + G S Sbjct: 171 IVERPVCKDSTRIRITDNMFCAYYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVS 230 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 +G C + G YT++ + WI+ + Sbjct: 231 WGE-GCDRDGKYGFYTHVFRLKKWIQKVI 258 >1SC8-U nrPDB Length = 262 Score = 247 bits (631), Expect = 3e-66, Method: Composition-based stats. Identities = 73/274 (26%), Positives = 123/274 (44%), Gaps = 34/274 (12%) Query: 8 LALSLGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKE-----HICGGVLLDRNWVLT 62 L G P + +++GG +QPW A+Y + ++CGG L+ WV++ Sbjct: 1 LKFQCGQKTLRP--RFKIIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVIS 58 Query: 63 AAHCYVD-----QYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADF 117 A HC++D Y V+LG+++L V H ++ L Sbjct: 59 ATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLA---------H 109 Query: 118 SNDLMLLRLSKP----ADITDVVKPIALPT--KEPKPGSKCLASGWGSITPTRWQKPDDL 171 ND+ LL++ A + ++ I+LP+ +P+ G+ C +G+G T + P+ L Sbjct: 110 HNDIALLKIRSKEGRCAQPSRTIQTISLPSMYNDPQFGTSCEITGFGKENSTDYLYPEQL 169 Query: 172 QCVFITLLPNENCAK--VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQG 225 + + L+ + C + Y +VT MLCA + D+C+ DSGGPL+C L G Sbjct: 170 KMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTG 229 Query: 226 TTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 S+G C P +YT + F WI+ + Sbjct: 230 IVSWGR-GCALKDKPGVYTRVSHFLPWIRSHTKE 262 >5FCR-A nrPDB Length = 234 Score = 246 bits (628), Expect = 9e-66, Method: Composition-based stats. Identities = 78/245 (31%), Positives = 121/245 (49%), Gaps = 23/245 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGKNK 79 ++GG +++P+ +V H+CGG LLD WVL+AAHC D +V LG + Sbjct: 1 ILGGQEAAAHARPYMASVQVNGTHVCGGTLLDEQWVLSAAHCMDGVTDDDSVQVLLGAHS 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L EP + V PHPG L +DL+L +LS+ A + V+P+ Sbjct: 61 LSAPEPYKRWYDVQSVVPHPGSRPDSL-----------EDDLILFKLSQNASLGPHVRPL 109 Query: 140 AL--PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KVYLQKVTDV 195 L KE +PG+ C +GWG +T ++PD L + ++++ C + VT Sbjct: 110 PLQYEDKEVEPGTLCDVAGWGVVTHA-GRRPDVLHQLRVSIMNRTTCNLRTYHDGVVTIN 168 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 M+CA +DTCR DSG PL+C ++G ++G CG P +YT + + WI++ Sbjct: 169 MMCA--ESNRRDTCRGDSGSPLVCGDAVEGVVTWGSRVCGNGKKPGVYTRVSSYRMWIEN 226 Query: 256 TMMKN 260 N Sbjct: 227 ITNGN 231 >4Z6A-H nrPDB Length = 249 Score = 245 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 72/249 (28%), Positives = 112/249 (44%), Gaps = 27/249 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD-----QYEVWLGKNK 79 +VGG C K PWQV + +CGG L++ WV++AAHC+ LG++ Sbjct: 1 IVGGKVCPKGECPWQVLLLVNGAQLCGGTLINTIWVVSAAHCFDKIKNWRNLIAVLGEHD 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L + + Q R V++ + ++D+ LLRL +P +TD V P+ Sbjct: 61 LSEHDGDEQSRRVAQVIIPSTY-----------VPGTTNHDIALLRLHQPVVLTDHVVPL 109 Query: 140 ALPTKEPKPGSKC-----LASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTD 194 LP + + L SGWG + R +L + + L ++C Y K+T+ Sbjct: 110 CLPERTFSERTLAFVRFSLVSGWGQLLD-RGATALELMVLNVPRLMTQDCEASYPGKITE 168 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFN 250 M CAG G KD+C+ DSGGP L G S+G C G +YT + ++ Sbjct: 169 YMFCAGYSDGSKDSCKGDSGGPHATHYRGTWYLTGIVSWG-QGCATVGHFGVYTRVSQYI 227 Query: 251 SWIKDTMMK 259 W++ M Sbjct: 228 EWLQKLMRS 236 >1C5M-D nrPDB Length = 255 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 65/246 (26%), Positives = 100/246 (40%), Gaps = 25/246 (10%) Query: 25 VVGGFNCKKNSQPWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYV--DQYEVWLGKNKLF 81 +VGG CK PWQ + + E CGG +L ++LTAAHC +++V +G Sbjct: 1 IVGGQECKDGECPWQALLINEENEGFCGGTILSEFYILTAAHCLYQAKRFKVRVGDRNTE 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 QEE V H F + D+ +LRL P V P L Sbjct: 61 QEEGGEAVHEVEVVIKHNRFTKET-----------YDFDIAVLRLKTPITFRMNVAPACL 109 Query: 142 PTKEPKPGS-----KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 P ++ + + SG+G + ++ L+ + + + +C +T M Sbjct: 110 PERDWAESTLMTQKTGIVSGFGRT-HEKGRQSTRLKMLEVPYVDRNSCKLSSSFIITQNM 168 Query: 197 LCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSW 252 CAG +D C+ DSGGP + + G S+G C + G IYT + F W Sbjct: 169 FCAGYDTKQEDACQGDSGGPHVTRFKDTYFVTGIVSWGE-GCARKGKYGIYTKVTAFLKW 227 Query: 253 IKDTMM 258 I +M Sbjct: 228 IDRSMK 233 >3F6U-H nrPDB Length = 240 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 117/251 (46%), Gaps = 29/251 (11%) Query: 26 VGGFNCKKNSQPWQVAVYYQKEHI-CGGVLLDRNWVLTAAHCYVDQYE--VWLGKNKLFQ 82 + G ++ PWQV + K+ + CG VL+ +WVLTAAHC + + V LG+ L + Sbjct: 2 IDGKMTRRGDSPWQVVLLDSKKKLACGAVLIHPSWVLTAAHCMDESKKLLVRLGEYDLRR 61 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 E + + F HP ++ S ND+ LL L++PA ++ + PI LP Sbjct: 62 WEKWELDLDIKEVFVHPNYSKSTT-----------DNDIALLHLAQPATLSQTIVPICLP 110 Query: 143 TKE------PKPGSKCLASGWG----SITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV 192 + G + L +GWG + + L + I ++P+ C++V V Sbjct: 111 DSGLAERELNQAGQETLVTGWGYHSSREKEAKRNRTFVLNFIKIPVVPHNECSEVMSNMV 170 Query: 193 TDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIK 248 ++ MLCAG +G +D C DSGGP++ L G S+G CG +YT + + Sbjct: 171 SENMLCAGILGDRQDACEGDSGGPMVASFHGTWFLVGLVSWGE-GCGLLHNYGVYTKVSR 229 Query: 249 FNSWIKDTMMK 259 + WI + Sbjct: 230 YLDWIHGHIRD 240 >1FIZ-A nrPDB Length = 263 Score = 245 bits (625), Expect = 2e-65, Method: Composition-based stats. Identities = 75/264 (28%), Positives = 121/264 (45%), Gaps = 39/264 (14%) Query: 25 VVGGFNCKKNSQPWQVAVY------YQKEHICGGVLLDRNWVLTAAHCYVDQYEV----- 73 VVGG + + + PW V++ ++ H CGG+LL+ +WVLTAAHC+ ++ +V Sbjct: 1 VVGGMSAEPGAWPWMVSLQIFMYHNNRRYHTCGGILLNSHWVLTAAHCFKNKKKVTDWRL 60 Query: 74 WLGKNKLFQEE-----PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 G N++ P Q R V + H + L + ND+ L++++ Sbjct: 61 IFGANEVVWGSNKPVKPPLQERFVEEIIIHEKYVSGLEI-----------NDIALIKITP 109 Query: 129 PADITDVVKPIALPT---KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 P + P LP P+ C +GWG + + LQ + L+ E C Sbjct: 110 PVPCGPFIGPGCLPQFKAGPPRAPQTCWVTGWGYLKEKGPRTSPTLQEARVALIDLELCN 169 Query: 186 --KVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG------ILQGTTSYGPVPCGKP 237 + Y ++ +CAG G DTC+ DSGGPL+C ++ G TS+G V C + Sbjct: 170 STRWYNGRIRSTNVCAGYPRGKIDTCQGDSGGPLMCRDRAENTFVVVGITSWG-VGCARA 228 Query: 238 GVPAIYTNLIKFNSWIKDTMMKNA 261 P +YT+ + +WI + NA Sbjct: 229 KRPGVYTSTWPYLNWIASKIGSNA 252 >4MPW-A nrPDB Length = 245 Score = 244 bits (624), Expect = 2e-65, Method: Composition-based stats. Identities = 78/258 (30%), Positives = 115/258 (44%), Gaps = 36/258 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYV-DQYEVWLGKNKL 80 +VGG ++ PWQV++ H CGG L+ WVLTAAHC D ++ + +L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVHGPYWMHFCGGSLIHPQWVLTAAHCVGPDVKDLAALRVQL 60 Query: 81 FQEEPSAQH--RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 ++ Q VS+ HP F A D+ LL L +P ++ V Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQF-----------YTAQIGADIALLELEEPVKVSSHVHT 109 Query: 139 IALP--TKEPKPGSKCLASGWGSI-TPTRWQKPDDLQCVFITLLPNENCAKVYL------ 189 + LP ++ PG C +GWG + R P L+ V + ++ N C Y Sbjct: 110 VTLPPASETFPPGMPCWVTGWGDVDNDERLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 169 Query: 190 ---QKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAI 242 + V D MLCAG +D+C+ DSGGPL+C + G S+G C +P P I Sbjct: 170 DDVRIVRDDMLCAGNT--RRDSCQGDSGGPLVCKVNGTWLQAGVVSWGE-GCAQPNRPGI 226 Query: 243 YTNLIKFNSWIKDTMMKN 260 YT + + WI + K Sbjct: 227 YTRVTYYLDWIHHYVPKK 244 >1YC0-A nrPDB Length = 283 Score = 244 bits (623), Expect = 3e-65, Method: Composition-based stats. Identities = 74/257 (28%), Positives = 114/257 (44%), Gaps = 29/257 (11%) Query: 19 PPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEV 73 L+ R++GG + S PW A+Y + C G L+ WV++AAHC+ D V Sbjct: 30 TFLRPRIIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSV 88 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKP---- 129 LG++ + Q + K P+ +++ +DL+L+RL K Sbjct: 89 VLGQHFFNRTTDVTQTFGIEKYIPYTLYSVF----------NPSDHDLVLIRLKKKGDRC 138 Query: 130 ADITDVVKPIALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK- 186 A + V+PI LP G KC +GWG + L+ + L+ + C+ Sbjct: 139 ATRSQFVQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSP 198 Query: 187 -VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPA 241 VY ++ MLCAG D C+ DSGGPL C+ L G S+G CG+ P Sbjct: 199 EVYGADISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPG 257 Query: 242 IYTNLIKFNSWIKDTMM 258 +YT + + WI D + Sbjct: 258 VYTRVANYVDWINDRIR 274 >2OQ5-A nrPDB Length = 232 Score = 243 bits (621), Expect = 6e-65, Method: Composition-based stats. Identities = 65/242 (26%), Positives = 105/242 (43%), Gaps = 23/242 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE-VWLGKNKLFQE 83 +VGG ++ PWQ ++ + H CG L++ W+++AAHC+ + Sbjct: 1 IVGGTEVEEGEWPWQASLQWDGSHRCGATLINATWLVSAAHCFTTYKNPARWTASFGVTI 60 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP- 142 +PS R + + H + D+ L LS P T+ V + LP Sbjct: 61 KPSKMKRGLRRIIVHEKYKH-----------PSHDYDISLAELSSPVPYTNAVHRVCLPD 109 Query: 143 -TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA--KVYLQKVTDVMLCA 199 + E +PG +G+G++ + + + L+ +TL+ C + Y +T MLCA Sbjct: 110 ASYEFQPGDVMFVTGFGALKNDGYSQ-NHLRQAQVTLIDATTCNEPQAYNDAITPRMLCA 168 Query: 200 GEMGGGKDTCRDDSGGPLICD-----GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 G + G D C+ DSGGPL+ L G S+G C KP P +YT + WI Sbjct: 169 GSLEGKTDACQGDSGGPLVSSDARDIWYLAGIVSWGD-ECAKPNKPGVYTRVTALRDWIT 227 Query: 255 DT 256 Sbjct: 228 SK 229 >6AOD-C nrPDB Length = 245 Score = 243 bits (620), Expect = 7e-65, Method: Composition-based stats. Identities = 78/244 (31%), Positives = 117/244 (47%), Gaps = 28/244 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCYVDQ-----YEVWLG 76 +VGG + PWQV ++ + H+CGG ++ W+LTAAHC+ V+ G Sbjct: 1 IVGGTASVRGEWPWQVTLHTTSPTQRHLCGGSIIGNQWILTAAHCFYGVESPKILRVYSG 60 Query: 77 KNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVV 136 + + + V + H + M A+ D+ LL+L TD Sbjct: 61 ILQQSEIKEDTSFFGVQEIIIHDQYKM-----------AESGYDIALLKLETTVQYTDSQ 109 Query: 137 KPIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ-KVT 193 +PI+LP+K + + C +GWG R + + LQ I L+ NE C K Y K+T Sbjct: 110 RPISLPSKGDRNVIYTDCWVTGWGYRK-LRDKIQNTLQKAKIPLVTNEECQKRYRGHKIT 168 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 M+CAG GGKD C+ D+GGPL C L G TS+G C + P +YTN++++ Sbjct: 169 HKMICAGYREGGKDACKGDAGGPLSCKHNEVWHLVGITSWGE-GCAQRERPGVYTNVVEY 227 Query: 250 NSWI 253 WI Sbjct: 228 VDWI 231 >5XRF-A nrPDB Length = 242 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 78/240 (32%), Positives = 113/240 (47%), Gaps = 13/240 (5%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK--EHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 V+GG C N + A + + C G L+ WVL AAHCY ++LG + Sbjct: 7 VIGGNECDTNEHRFLAAFFTSRPWTFQCAGTLIHEEWVLAAAHCYKRGLNIYLGMHNQSI 66 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 + Q R + + + + D++LL+L+KP + + P++LP Sbjct: 67 QFDDEQRR----------YAIEEHYYRCDEKLTKWEKDVVLLKLNKPVSNSTHIAPLSLP 116 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKV-TDVMLCAGE 201 + P GS C GWG ++ T+ PD C I LL C Y T +LCAG Sbjct: 117 SSPPSIGSVCRVMGWGIMSSTKDILPDVPHCANINLLNYMECVAHYPDVPETTRLLCAGV 176 Query: 202 MGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 + GG DTC DSGGPLICDG QG +G PC +P P +YT + +N WI++ + Sbjct: 177 LEGGIDTCNQDSGGPLICDGQFQGIVFFGKYPCAQPNKPGLYTRVSNYNDWIQNIIAGKT 236 >5LHN-A nrPDB Length = 247 Score = 242 bits (618), Expect = 1e-64, Method: Composition-based stats. Identities = 72/257 (28%), Positives = 118/257 (45%), Gaps = 33/257 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK------EHICGGVLLDRNWVLTAAHCY-----VDQYEV 73 +VGG + +QPW A+Y + CGG L+ WV +AAHC+ + Y V Sbjct: 1 IVGGEFTEVENQPWFAAIYQKNKGGSPPSFKCGGSLISPCWVASAAHCFIQLPKKENYVV 60 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKP---- 129 +LG++K P V + H + L + ND+ LL++ Sbjct: 61 YLGQSKESSYNPGEMKFEVEQLILHEYYREDSLA---------YHNDIALLKIRTSTGQC 111 Query: 130 ADITDVVKPIALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK- 186 A + ++ IALP + + GS C +G+G + + + P +L+ + L+ +E C + Sbjct: 112 AQPSRSIQTIALPPRFTDAPFGSDCEITGFGKESESDYLYPKNLKMSVVKLVSHEQCMQP 171 Query: 187 -VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPA 241 Y ++ MLCA + D+C+ DSGGPLIC+ L G S+G C + P Sbjct: 172 HYYGSEINYKMLCAADPEWKTDSCKGDSGGPLICNIEGRPTLSGIVSWGR-GCAEKNKPG 230 Query: 242 IYTNLIKFNSWIKDTMM 258 +YT + F WI+ + Sbjct: 231 VYTRVSHFLDWIQSHIG 247 >3P8G-A nrPDB Length = 241 Score = 242 bits (617), Expect = 2e-64, Method: Composition-based stats. Identities = 81/251 (32%), Positives = 116/251 (46%), Gaps = 32/251 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQ----------YEV 73 VVGG + + PWQV+++ + HICG L+ NW+++AAHCY+D + Sbjct: 1 VVGGTDADEGEWPWQVSLHALGQGHICGASLISPNWLVSAAHCYIDDRGFRYSDPTQWTA 60 Query: 74 WLGKNKLFQEE-PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADI 132 +LG + Q P Q R + + HP FN F D+ LL L KPA+ Sbjct: 61 FLGLHDQSQRSAPGVQERRLKRIISHPFFN-----------DFTFDYDIALLELEKPAEY 109 Query: 133 TDVVKPIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ 190 + +V+PI LP G +GWG LQ I ++ C + Q Sbjct: 110 SSMVRPICLPDASHVFPAGKAIWVTGWGHT-QYGGTGALILQKGEIRVIQQTTCENLLPQ 168 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLI---CDG--ILQGTTSYGPVPCGKPGVPAIYTN 245 ++T M+C G + GG D+C+ DSGGPL DG G S+G C + P +YT Sbjct: 169 QITPRMMCVGFLSGGVDSCQGDSGGPLSSVEADGRIFQAGVVSWGD-GCAQRNKPGVYTR 227 Query: 246 LIKFNSWIKDT 256 L F WIK+ Sbjct: 228 LPLFRDWIKEN 238 >1MZD-A nrPDB Length = 240 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 83/244 (34%), Positives = 122/244 (50%), Gaps = 23/244 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC-----YVDQYEVWLGKNK 79 ++GG +S+P+ ++ Y H+CGGVL+D WVLTAAHC V LG + Sbjct: 3 IIGGKEVSPHSRPFMASIQYGGHHVCGGVLIDPQWVLTAAHCQYRFTKGQSPTVVLGAHS 62 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L + E S Q + K P + SND+ML++L A + VK + Sbjct: 63 LSKNEASKQTLEIKKFIP-----------FSRVTSDPQSNDIMLVKLQTAAKLNKHVKML 111 Query: 140 ALPTKEP-KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKVYLQ--KVTD 194 + +K + G+KC +GWG+ P + D L+ V +T+L + C Y +T Sbjct: 112 HIRSKTSLRSGTKCKVTGWGATDPDSLRPSDTLREVTVTVLSRKLCNSQSYYNGDPFITK 171 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLI-KFNSWI 253 M+CAG+ G KD+C+ D+GGPLIC G+ S G CG P IYT L K+ +WI Sbjct: 172 DMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIVSGGH-ECGVATKPGIYTLLTKKYQTWI 230 Query: 254 KDTM 257 K + Sbjct: 231 KSNL 234 >4H4F-A nrPDB Length = 249 Score = 241 bits (616), Expect = 2e-64, Method: Composition-based stats. Identities = 76/251 (30%), Positives = 117/251 (46%), Gaps = 30/251 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKN 78 VVGG + + +S PWQ+++ Y K H CGG L+ N+VLTAAHC + Y V +GKN Sbjct: 1 VVGGEDARPHSWPWQISLQYLKNDTWRHTCGGTLIASNFVLTAAHCISNTRTYRVAVGKN 60 Query: 79 KLF-QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 L ++E + V H +N LL ND+ L++L++ +++D ++ Sbjct: 61 NLEVEDEEGSLFVGVDTIHVHKRWNALLLR-----------NDIALIKLAEHVELSDTIQ 109 Query: 138 PIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQKVT 193 LP K+ C +GWG + T D LQ ++ + C++ + +V Sbjct: 110 VACLPEKDSLLPKDYPCYVTGWGRLW-TNGPIADKLQQGLQPVVDHATCSRIDWWGFRVK 168 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLICD-----GILQGTTSYGP-VPCGKPGVPAIYTNLI 247 M+CAG G C DSGGPL C + G S+G C P +YT + Sbjct: 169 KTMVCAGG-DGVISACNGDSGGPLNCQLENGSWEVFGIVSFGSRRGCNTRKKPVVYTRVS 227 Query: 248 KFNSWIKDTMM 258 + WI + M Sbjct: 228 AYIDWINEKMQ 238 >1KYN-A nrPDB Length = 235 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 71/240 (29%), Positives = 118/240 (49%), Gaps = 21/240 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ---KEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++GG + +S+P+ + Q + CGG L+ ++VLTAAHC+ V LG + + Sbjct: 1 IIGGRESRPHSRPYMAYLQIQSPAGQSRCGGFLVREDFVLTAAHCWGSNINVTLGAHNIQ 60 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + E + QH ++ HP +N + ND+MLL+LS+ V P+AL Sbjct: 61 RRENTQQHITARRAIRHPQYNQRTI-----------QNDIMLLQLSRRVRRNRNVNPVAL 109 Query: 142 PTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCA 199 P + +PG+ C +GWG ++ R D L+ V + + + C +++ +C Sbjct: 110 PRAQEGLRPGTLCTVAGWGRVSMRRGT--DTLREVQLRVQRDRQCLRIFGSYDPRRQICV 167 Query: 200 GEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 G+ K + DSGGPL+C+ + G SYG G P P ++T + F WI+ TM Sbjct: 168 GDRRERKAAFKGDSGGPLLCNNVAHGIVSYGKSS-GVP--PEVFTRVSSFLPWIRTTMRS 224 >1ORF-A nrPDB Length = 234 Score = 241 bits (615), Expect = 2e-64, Method: Composition-based stats. Identities = 85/244 (34%), Positives = 130/244 (53%), Gaps = 21/244 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHC-YVDQYEVWLGKNKLFQE 83 ++GG +S+P+ V + ++ IC G L+ ++WVLTAAHC + +V LG + + +E Sbjct: 1 IIGGNEVTPHSRPYMVLLSLDRKTICAGALIAKDWVLTAAHCNLNKRSQVILGAHSITRE 60 Query: 84 EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPT 143 EP+ Q LV K FP+P ++ A DL LL+L++ A I V + LP Sbjct: 61 EPTKQIMLVKKEFPYPCYDP-----------ATREGDLKLLQLTEKAKINKYVTILHLPK 109 Query: 144 K--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKV----YLQKVTDVML 197 K + KPG+ C +GWG T D L+ V IT++ + C + + M+ Sbjct: 110 KGDDVKPGTMCQVAGWGR-THNSASWSDTLREVEITIIDRKVCNDRNHYNFNPVIGMNMV 168 Query: 198 CAGEMGGGKDTCRDDSGGPLICDGILQGTTSYG-PVPCGKPGVPAIYTNLI-KFNSWIKD 255 CAG + GG+D+C DSG PL+C+G+ +G TS+G CG P P +Y L K +WI Sbjct: 169 CAGSLRGGRDSCNGDSGSPLLCEGVFRGVTSFGLENKCGDPRGPGVYILLSKKHLNWIIM 228 Query: 256 TMMK 259 T+ Sbjct: 229 TIKG 232 >1BDA-A nrPDB Length = 265 Score = 240 bits (614), Expect = 4e-64, Method: Composition-based stats. Identities = 77/266 (28%), Positives = 120/266 (45%), Gaps = 41/266 (15%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKE------HICGGVLLDRNWVLTAAHCYVDQY---- 71 Q R+ GG S PWQ A++ + +CGG+L+ W+L+AAHC+ +++ Sbjct: 11 QFRIKGGLFADIASHPWQAAIFAKHRRSPGERFLCGGILISSCWILSAAHCFQERFPPHH 70 Query: 72 -EVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS--- 127 V LG+ Q V K H F+ + ND+ LL+L Sbjct: 71 LTVILGRTYRVVPGEEEQKFEVEKYIVHKEFDDDT-----------YDNDIALLQLKSDS 119 Query: 128 -KPADITDVVKPIALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 + A + VV+ + LP + + ++C SG+G + L+ + L P+ C Sbjct: 120 SRCAQESSVVRTVCLPPADLQLPDWTECELSGYGKHEALSPFYSERLKEAHVRLYPSSRC 179 Query: 185 AKVY--LQKVTDVMLCAGEMGGGK------DTCRDDSGGPLIC----DGILQGTTSYGPV 232 + + VTD MLCAG+ G D C+ DSGGPL+C L G S+G + Sbjct: 180 TSQHLLNRTVTDNMLCAGDTRSGGPQANLHDACQGDSGGPLVCLNDGRMTLVGIISWG-L 238 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTMM 258 CG+ VP +YT + + WI+D M Sbjct: 239 GCGQKDVPGVYTKVTNYLDWIRDNMR 264 >1LTO-A nrPDB Length = 245 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 114/258 (44%), Gaps = 36/258 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE---HICGGVLLDRNWVLTAAHCYV-DQYEVWLGKNKL 80 +VGG ++ PWQV++ + H CGG L+ WVLTAAHC D ++ + +L Sbjct: 1 IVGGQEAPRSKWPWQVSLRVRDRYWMHFCGGSLIHPQWVLTAAHCLGPDVKDLATLRVQL 60 Query: 81 FQEEPSAQH--RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 ++ Q VS+ HP F D+ LL L +P +I+ V Sbjct: 61 REQHLYYQDQLLPVSRIIVHPQF-----------YIIQTGADIALLELEEPVNISSRVHT 109 Query: 139 IALP--TKEPKPGSKCLASGWGSITPTRW-QKPDDLQCVFITLLPNENCAKVYL------ 189 + LP ++ PG C +GWG + P L+ V + ++ N C Y Sbjct: 110 VMLPPASETFPPGMPCWVTGWGDVDNDEPLPPPFPLKQVKVPIMENHICDAKYHLGAYTG 169 Query: 190 ---QKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSYGPVPCGKPGVPAI 242 + + D MLCAG +D+C+ DSGGPL+C + G S+ C +P P I Sbjct: 170 DDVRIIRDDMLCAGNS--QRDSCKGDSGGPLVCKVNGTWLQAGVVSW-DEGCAQPNRPGI 226 Query: 243 YTNLIKFNSWIKDTMMKN 260 YT + + WI + K Sbjct: 227 YTRVTYYLDWIHHYVPKK 244 >5TO3-B nrPDB Length = 409 Score = 238 bits (608), Expect = 2e-63, Method: Composition-based stats. Identities = 70/265 (26%), Positives = 114/265 (43%), Gaps = 43/265 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + + ++ K + HP +N + D+ L++L KP Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT-----RWQKPDDLQCVFITLLPN 181 +D + P+ LP +E + G K +GWG++ T +P LQ V + ++ Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKETWTANVGKGQPSVLQVVNLPIVER 170 Query: 182 ENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD------GILQGTTSYGPV 232 C ++TD M CAG G D C DSGGP + G S G Sbjct: 171 PVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPFNNRWYQMGIVSAGA- 229 Query: 233 PCGKPGVPAIYTNLIKFNSWIKDTM 257 C + G YT++ + WI+ + Sbjct: 230 GCDRDGKYGFYTHVFRLKKWIQKVI 254 >2V35-A nrPDB Length = 240 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 75/251 (29%), Positives = 118/251 (47%), Gaps = 26/251 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE----HICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKN 78 VVGG ++NS P Q+++ Y+ H CGG L+ +NWV+TAAHC + + V +G++ Sbjct: 1 VVGGTEAQRNSWPSQISLQYRSGSSWAHTCGGTLIRQNWVMTAAHCVDRELTFRVVVGEH 60 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 L Q + + Q+ V K HP +N + D+ LLRL++ + V+ Sbjct: 61 NLNQNDGTEQYVGVQKIVVHPYWNTDDVAA---------GYDIALLRLAQSVTLNSYVQL 111 Query: 139 IALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKVYLQKVTD 194 LP S C +GWG +T T Q LQ ++ + C + + V + Sbjct: 112 GVLPRAGTILANNSPCYITGWG-LTRTNGQLAQTLQQAYLPTVDYAICSSSSYWGSTVKN 170 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPV-PCGKPGVPAIYTNLIKF 249 M+CAG G + C+ DSGGPL C + G TS+ C P ++T + + Sbjct: 171 SMVCAGG-DGVRSGCQGDSGGPLHCLVNGQYAVHGVTSFVSRLGCNVTRKPTVFTRVSAY 229 Query: 250 NSWIKDTMMKN 260 SWI + + N Sbjct: 230 ISWINNVIASN 240 >2XRC-A nrPDB Length = 565 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 75/265 (28%), Positives = 112/265 (42%), Gaps = 33/265 (12%) Query: 6 LFLALSLGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAH 65 L LS G + + R+VGG + PWQVA+ CGG+ + W+LTAAH Sbjct: 303 LLPKLSCGVKNRMHIRRKRIVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAH 362 Query: 66 CYV----DQYEVWLGKNKLFQEE-PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSND 120 C +Y++W + V + H +N + ND Sbjct: 363 CLRASKTHRYQIWTTVVDWIHPDLKRIVIEYVDRIIFHENYN-----------AGTYQND 411 Query: 121 LMLLRLSKPADITDVVKPIALPTKEP------KPGSKCLASGWGSITPTRWQKPDDLQCV 174 + L+ + K + D P ++P P +P C+ SGWG ++ LQ Sbjct: 412 IALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWG 469 Query: 175 FITLLPNENCAKVYLQKVTD-VMLCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTS 228 + L+ N C+K Y + + M CAG G D C+ DSGGPL+C + G S Sbjct: 470 EVKLISN--CSKFYGNRFYEKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVS 527 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWI 253 +G CGKP P +YT + + WI Sbjct: 528 WGEN-CGKPEFPGVYTKVANYFDWI 551 >1PYT-D nrPDB Length = 251 Score = 238 bits (607), Expect = 2e-63, Method: Composition-based stats. Identities = 76/263 (28%), Positives = 119/263 (45%), Gaps = 29/263 (11%) Query: 12 LGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCY 67 G P L +RVVGG + +S PWQ+++ Y + H CGG L+ N VLTAAHC Sbjct: 1 CGAPIFQPNLSARVVGGEDAIPHSWPWQISLQYLRDNTWRHTCGGTLITPNHVLTAAHCI 60 Query: 68 VD--QYEVWLGKNKLFQEEP-SAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLL 124 + Y V LGKN L E+ + + V F H +N L+ ND+ L+ Sbjct: 61 SNTLTYRVALGKNNLEVEDEAGSLYVGVDTIFVHEKWNSFLVR-----------NDIALI 109 Query: 125 RLSKPADITDVVKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNE 182 +L++ ++ D ++ LP++ C +GWG + T +LQ ++ Sbjct: 110 KLAETVELGDTIQVACLPSEGSLLPQDYPCFVTGWGRLY-TNGPIAAELQQGLQPVVDYA 168 Query: 183 NCAK--VYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPV-PCG 235 C++ + V + M+CAG G C DSGGPL C ++G S+G C Sbjct: 169 TCSQRDWWGTTVKETMVCAGG-DGVISACNGDSGGPLNCQADGQWDVRGIVSFGSGLSCN 227 Query: 236 KPGVPAIYTNLIKFNSWIKDTMM 258 P ++T + + WI + Sbjct: 228 TFKKPTVFTRVSAYIDWINQKLQ 250 >1FIW-A nrPDB Length = 290 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 70/264 (26%), Positives = 117/264 (44%), Gaps = 39/264 (14%) Query: 25 VVGGFNCKKNSQPWQVAVY------YQKEHICGGVLLDRNWVLTAAHCY-----VDQYEV 73 ++GG + + PW V++ ++ H+CGG LL+ W+LTAAHC+ V + + Sbjct: 1 IIGGQDAAHGAWPWMVSLQIFTYHNNRRYHVCGGSLLNSQWLLTAAHCFRIKKKVTDWRL 60 Query: 74 WLGKNKLFQE-----EPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 G ++ +P Q R V K H ++ S +ND+ L++++ Sbjct: 61 IFGAKEVEWGTNKPVKPPLQERYVEKIIIHEKYSAS-----------SEANDIALMKITP 109 Query: 129 PADITDVVKPIALPT---KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 P + P LP P+ C +GWG + + LQ + L+ C Sbjct: 110 PVTCGHFIGPGCLPQFRAGPPRVPQTCWVAGWGFLQENARRTSPMLQEARVDLIDLGLCN 169 Query: 186 --KVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG------ILQGTTSYGPVPCGKP 237 + Y ++ +CAG G DTC+ DSGGPL+C ++ G TS+G V C + Sbjct: 170 STRWYNGRIRSTNVCAGYPEGKIDTCQGDSGGPLMCKDSAENSYVVVGITSWG-VGCARA 228 Query: 238 GVPAIYTNLIKFNSWIKDTMMKNA 261 P +YT+ + +WI + A Sbjct: 229 KRPGVYTSTWSYLNWIASKIGSTA 252 >1AZZ-A nrPDB Length = 226 Score = 237 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 71/232 (30%), Positives = 113/232 (48%), Gaps = 15/232 (6%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKNKLFQ 82 +VGG NS P Q A++ + CGG L+ W+LTAAHC +V LG + + + Sbjct: 1 IVGGVEAVPNSWPHQAALFIDDMYFCGGSLISPEWILTAAHCMDGAGFVDVVLGAHNIRE 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 +E + + H +N ++ SND+ ++RL P +T + + LP Sbjct: 61 DEATQVTIQSTDFTVHENYNSFVI-----------SNDIAVIRLPVPVTLTAAIATVGLP 109 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEM 202 + + G+ +GWG + + D L+ V + ++ N +C VY VTD +C + Sbjct: 110 STDVGVGTVVTPTGWGLPSDSALGISDVLRQVDVPIMSNADCDAVY-GIVTDGNICI-DS 167 Query: 203 GGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 GGK TC DSGGPL +G+ G TS+G + G P +T + F WI+ Sbjct: 168 TGGKGTCNGDSGGPLNYNGLTYGITSFGAAAGCEAGYPDAFTRVTYFLDWIQ 219 >2RDL-A nrPDB Length = 226 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 77/242 (31%), Positives = 120/242 (49%), Gaps = 22/242 (9%) Query: 25 VVGGFNCKKNSQPWQVAV--YYQKEHI--CGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG C+ +++P+ + + H+ C G L+ RN+V+TAAHC V LG + Sbjct: 1 IIGGTECRPHARPYMAYLEIVTPENHLSACSGFLIRRNFVMTAAHCAGRSITVLLGAHNK 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK--P 138 +E + Q V K FPHP ++ L++ ND+MLL+L + A++T V P Sbjct: 61 KVKEDTWQKLEVEKQFPHPKYDDRLVL-----------NDIMLLKLKEKANLTLGVGTLP 109 Query: 139 IALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 I+ + PG C A GWG T D LQ V + +L + C K + + LC Sbjct: 110 ISAKSNSIPPGRVCRAVGWGR-TNVNEPPSDTLQEVKMRILDPQAC-KHFEDFHQEPQLC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G ++ + DSGGPL+C GI QG SY KP P+++T + + WI + Sbjct: 168 VGNPKKIRNVYKGDSGGPLLCAGIAQGIASYVLRN-AKP--PSVFTRISHYRPWINKILR 224 Query: 259 KN 260 +N Sbjct: 225 EN 226 >2R0L-A nrPDB Length = 248 Score = 236 bits (603), Expect = 7e-63, Method: Composition-based stats. Identities = 72/251 (28%), Positives = 111/251 (44%), Gaps = 29/251 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGKNK 79 ++GG + S PW A+Y + C G L+ WV++AAHC+ D V LG++ Sbjct: 1 IIGGSSSLPGSHPWLAAIYI-GDSFCAGSLVHTCWVVSAAHCFSHSPPRDSVSVVLGQHF 59 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKP----ADITDV 135 + Q + K P+ +++ +DL+L+RL K A + Sbjct: 60 FNRTTDVTQTFGIEKYIPYTLYSVF----------NPSDHDLVLIRLKKKGDRCATRSQF 109 Query: 136 VKPIALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQK 191 V+PI LP G KC +GWG + L+ + L+ + C+ VY Sbjct: 110 VQPICLPEPGSTFPAGHKCQIAGWGHLDENVSGYSSSLREALVPLVADHKCSSPEVYGAD 169 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKPGVPAIYTNLI 247 ++ MLCAG D C+ DSGGPL C+ L G S+G CG+ P +YT + Sbjct: 170 ISPNMLCAGYFDCKSDACQGDSGGPLACEKNGVAYLYGIISWGD-GCGRLHKPGVYTRVA 228 Query: 248 KFNSWIKDTMM 258 + WI D + Sbjct: 229 NYVDWINDRIR 239 >4XDE-A nrPDB Length = 257 Score = 235 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 77/252 (30%), Positives = 114/252 (45%), Gaps = 34/252 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD-----QYEVWLGKNK 79 VVGG + + P+ A+Y+ C G L+ WVLTAAHC D V LG+ + Sbjct: 3 VVGGLVALRGAHPYIAALYWGHS-FCAGSLIAPCWVLTAAHCLQDRPAPEDLTVVLGQER 61 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD-----ITD 134 Q V H F+ + +DL LLRL + AD ++ Sbjct: 62 RNHSCEPCQTLAVRSYRLHEAFSP-----------VSYQHDLALLRLQEDADGSCALLSP 110 Query: 135 VVKPIALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQ 190 V+P++LP+ P + C +GWG + LQ + L E C+ V+ Sbjct: 111 YVQPVSLPSGAARPSETTLCQVAGWGHQFEGAEEYASFLQEAQVPFLSLERCSAPDVHGS 170 Query: 191 KVTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTSYGPVPCGKPGVPAIY 243 + MLCAG + GG D C+ DSGGPL+C+ LQG S+G CG P +Y Sbjct: 171 SILPGMLCAGFLEGGTDACQGDSGGPLVCEDQAAERRLTLQGIISWGS-GCGDRNKPGVY 229 Query: 244 TNLIKFNSWIKD 255 T++ + +WI++ Sbjct: 230 TDVAYYLAWIRE 241 >1A5I-A nrPDB Length = 265 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 80/260 (30%), Positives = 121/260 (46%), Gaps = 41/260 (15%) Query: 27 GGFNCKKNSQPWQVAVYYQKE------HICGGVLLDRNWVLTAAHCYVDQY-----EVWL 75 GG S PWQ A++ Q +CGG+L+ WVLTAAHC+ + Y +V L Sbjct: 16 GGLFTDITSHPWQAAIFAQNRRSSGERFLCGGILISSCWVLTAAHCFQESYLPDQLKVVL 75 Query: 76 GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS----KPAD 131 G+ + Q V K H F+ ++ND+ LL+L + A Sbjct: 76 GRTYRVKPGEEEQTFKVKKYIVHKEFDDDT-----------YNNDIALLQLKSDSPQCAQ 124 Query: 132 ITDVVKPIALPTKEPK--PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKV 187 +D V+ I LP + ++C SG+G + + L+ + L P+ C + Sbjct: 125 ESDSVRAICLPEANLQLPDWTECELSGYGKHKSSSPFYSEQLKEGHVRLYPSSRCAPKFL 184 Query: 188 YLQKVTDVMLCAGEMGGGK------DTCRDDSGGPLIC----DGILQGTTSYGPVPCGKP 237 + + VT+ MLCAG+ G+ D C+ DSGGPL+C L G S+G V CG+ Sbjct: 185 FNKTVTNNMLCAGDTRSGEIYPNVHDACQGDSGGPLVCMNDNHMTLLGIISWG-VGCGEK 243 Query: 238 GVPAIYTNLIKFNSWIKDTM 257 VP +YT + + WI+D M Sbjct: 244 DVPGVYTKVTNYLGWIRDNM 263 >1Q3X-A nrPDB Length = 328 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 80/263 (30%), Positives = 112/263 (42%), Gaps = 38/263 (14%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------ 70 +A R+ GG K PWQV + G LL NWVLTAAH +Q Sbjct: 79 SARTTGGRIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASA 136 Query: 71 YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 ++ +G L + P F H G+ A F ND+ L++L+ Sbjct: 137 LDIRMG--TLKRLSPHYTQAWSEAVFIHEGYTHD----------AGFDNDIALIKLNNKV 184 Query: 131 DITDVVKPIALPTKEPK----PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK 186 I + PI LP KE + ASGWG R +L V I ++ ++ C Sbjct: 185 VINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTA 242 Query: 187 VY------LQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPC 234 Y VT MLCAG GGKD+CR DSGG L+ + G S+G + C Sbjct: 243 AYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNC 302 Query: 235 GKPGVPAIYTNLIKFNSWIKDTM 257 G+ G +YT +I + WI++ + Sbjct: 303 GEAGQYGVYTKVINYIPWIENII 325 >3RP2-A nrPDB Length = 224 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 73/239 (30%), Positives = 109/239 (45%), Gaps = 22/239 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEH----ICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++GG +S+P+ + E ICGG L+ R +VLTAAHC + V LG + + Sbjct: 1 IIGGVESIPHSRPYMAHLDIVTEKGLRVICGGFLISRQFVLTAAHCKGREITVILGAHDV 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + E + Q V K H +N +D+MLL+L K ++T V + Sbjct: 61 RKRESTQQKIKVEKQIIHESYN-----------SVPNLHDIMLLKLEKKVELTPAVNVVP 109 Query: 141 LPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 LP+ PG+ C A+GWG T R L+ V + ++ + C Y +C Sbjct: 110 LPSPSDFIHPGAMCWAAGWGK-TGVRDPTSYTLREVELRIMDEKACVD-YRYYEYKFQVC 167 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G + DSGGPL+C G+ G SYG P KP PAI+T + + WI + Sbjct: 168 VGSPTTLRAAFMGDSGGPLLCAGVAHGIVSYGH-PDAKP--PAIFTRVSTYVPWINAVI 223 >4KKD-A nrPDB Length = 433 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 76/288 (26%), Positives = 122/288 (42%), Gaps = 57/288 (19%) Query: 16 DAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEH-------ICGGVLLDRNWVLTAAHCYV 68 + P L R++GG N + PWQ + + G LL +W+LTAAH Sbjct: 146 RSLPSLVQRIIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLR 205 Query: 69 DQYE-------------VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGA 115 Q V+LG + + +++ A + ++ HP FN+ Sbjct: 206 SQRRDTTVIPVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQ----------- 253 Query: 116 DFSNDLMLLRLSKPADITDVVKPIALPT---KEPKPGSKCLASGWGS----------ITP 162 ++++D+ L++L +P + V P+ LP + P P L +GWG I+ Sbjct: 254 NYNHDIALVQLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISS 313 Query: 163 TRWQKPDDLQCVFITLLPNENCAKVYLQK-----VTDVMLCAGEMGGGKDTCRDDSGGPL 217 D LQ V + ++P+ C Y + VT+ M CAG GGKDTC DSG Sbjct: 314 GTRTLSDVLQYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGEAF 373 Query: 218 I------CDGILQGTTSY-GPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 + ++QG S+ GP CG V +YT + + W+ + M Sbjct: 374 VIFDDLSQRWVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMG 421 >4Q7Y-A nrPDB Length = 250 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 70/245 (28%), Positives = 115/245 (46%), Gaps = 20/245 (8%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 80 ++GG +S+P+ +V + +H CGG LL WV++AAHC+ + V LG + L Sbjct: 1 IIGGHEVTPHSRPYMASVRFGGQHHCGGFLLRARWVVSAAHCFSHRDLRTGLVVLGAHVL 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 EP+ Q + HP ++ +ND+ LLRL+ A + V + Sbjct: 61 STAEPTQQVFGIDALTTHPDYHP-----------MTHANDICLLRLNGSAVLGPAVGLLR 109 Query: 141 LP---TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVML 197 LP + P G++C +GWG ++ + P L + +L + C + +T ML Sbjct: 110 LPGRRARPPTAGTRCRVAGWGFVSDFE-ELPPGLMEAKVRVLDPDVCNSSWKGHLTLTML 168 Query: 198 CAG-EMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 C + C DSGGPL+C G S+ + CG P P +YT + F +WI D Sbjct: 169 CTRSGDSHRRGFCSADSGGPLVCRNRAHGLVSFSGLWCGDPKTPDVYTQVSAFVAWIWDV 228 Query: 257 MMKNA 261 + +++ Sbjct: 229 VRRSS 233 >1FUJ-A nrPDB Length = 221 Score = 233 bits (595), Expect = 5e-62, Method: Composition-based stats. Identities = 70/243 (28%), Positives = 116/243 (47%), Gaps = 31/243 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCYVD----QYEVWLGK 77 +VGG + +S+P+ ++ + H CGG L+ ++VLTAAHC D V LG Sbjct: 1 IVGGHEAQPHSRPYMASLQMRGNPGSHFCGGTLIHPSFVLTAAHCLRDIPQRLVNVVLGA 60 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 + + +EP+ QH V++ F + ++ + ND++L++LS PA+++ V Sbjct: 61 HNVRTQEPTQQHFSVAQVFLN-NYD-----------AENKLNDILLIQLSSPANLSASVA 108 Query: 138 PIALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDV 195 + LP ++ G++CLA GWG + LQ + +T++ C Sbjct: 109 TVQLPQQDQPVPHGTQCLAMGWGRVGAHDPP-AQVLQELNVTVVTF-FCR--------PH 158 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 +C C DSGGPLICDGI+QG S+ C P +T + + WI+ Sbjct: 159 NICTFVPRRKAGICFGDSGGPLICDGIIQGIDSFVIWGCATRLFPDFFTRVALYVDWIRS 218 Query: 256 TMM 258 T+ Sbjct: 219 TLR 221 >2XXL-A nrPDB Length = 408 Score = 232 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 81/272 (29%), Positives = 123/272 (45%), Gaps = 29/272 (10%) Query: 15 IDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYV-- 68 D L RV G+ K +S+PW + YQ+ +CGG ++ ++LTAAHC Sbjct: 109 FDCGNFLSQRVSNGYEVKLSSRPWMALLRYQQFGESRFLCGGAMISERYILTAAHCVHGL 168 Query: 69 --DQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSL--LMLQTIPPGADFSNDLMLL 124 D YE+ LG++++ EE Q K P P N+ + ++ +D+ LL Sbjct: 169 QNDLYEIRLGEHRISTEEDCRQQGRKKKCAP-PVVNVGIEKHLIHEKYDARHIMHDIALL 227 Query: 125 RLSKPADITDVVKPIALPTKE-----PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLL 179 +L++ +KPI LP + + S +GWG T D L + L Sbjct: 228 KLNRSVPFQKHIKPICLPITDELKEKAEQISTYFVTGWG--TTENGSSSDVLLQANVPLQ 285 Query: 180 PNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC----------DGILQGTTSY 229 P C++ Y + V LC G G +D+C+ DSGGPL + G S Sbjct: 286 PRSACSQAYRRAVPLSQLCVGG-GDLQDSCKGDSGGPLQAPAQYLGEYAPKMVEFGIVSQ 344 Query: 230 GPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 G V CG+ +P +YTN+ ++ WI DTM N Sbjct: 345 GVVTCGQISLPGLYTNVGEYVQWITDTMASNG 376 >4IGD-A nrPDB Length = 406 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 76/273 (27%), Positives = 120/273 (43%), Gaps = 42/273 (15%) Query: 12 LGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYY-QKEHICGGVLLDRNWVLTAAHCY--- 67 G + L +++ G +K + PW + + + CGG LL +W++TAAHC Sbjct: 143 CGLPKFSRKLMAQIFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQS 202 Query: 68 ---------------VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIP 112 +++ LGK+ + + + QH V + HP ++ + Sbjct: 203 LDPEDPTLRDSDLLSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNT------- 255 Query: 113 PGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQ 172 F ND+ L+ L + + V PI LP + G+ + SGWG R P+ L Sbjct: 256 ----FENDVALVELLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQR--FPETLM 309 Query: 173 CVFITLLPNENCAKVY---LQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGIL 223 + I ++ + C K Y +KVT M+CAGE GGKD C DSGGP++ L Sbjct: 310 EIEIPIVDHSTCQKAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYL 369 Query: 224 QGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 GT S+G CGK +Y+ + WI+ Sbjct: 370 VGTVSWGD-DCGKKDRYGVYSYIHHNKDWIQRV 401 >1ZJK-A nrPDB Length = 403 Score = 230 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 79/263 (30%), Positives = 112/263 (42%), Gaps = 38/263 (14%) Query: 17 AAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------ 70 +A ++ GG K PWQV + G LL NWVLTAAH +Q Sbjct: 154 SARTTGGQIYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASA 211 Query: 71 YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 ++ +G L + P F H G+ A F ND+ L++L+ Sbjct: 212 LDIRMG--TLKRLSPHYTQAWSEAVFIHEGYTHD----------AGFDNDIALIKLNNKV 259 Query: 131 DITDVVKPIALPTKEPK----PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK 186 I + PI LP KE + ASGWG R +L V I ++ ++ C Sbjct: 260 VINSNITPICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTA 317 Query: 187 VY------LQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPC 234 Y VT MLCAG GGKD+CR DSGG L+ + G S+G + C Sbjct: 318 AYEKPPYPRGSVTANMLCAGLESGGKDSCRGDSGGALVFLDSETERWFVGGIVSWGSMNC 377 Query: 235 GKPGVPAIYTNLIKFNSWIKDTM 257 G+ G +YT +I + WI++ + Sbjct: 378 GEAGQYGVYTKVINYIPWIENII 400 >4IW4-E nrPDB Length = 279 Score = 230 bits (586), Expect = 7e-61, Method: Composition-based stats. Identities = 74/279 (26%), Positives = 119/279 (42%), Gaps = 57/279 (20%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEH-------ICGGVLLDRNWVLTAAHCYVDQYE----- 72 ++GG N + PWQ + + G LL +W+LTAAH Q Sbjct: 1 IIGGRNAEPGLFPWQALIVVEDTSRVPNDKWFGSGALLSASWILTAAHVLRSQRRDTTVI 60 Query: 73 --------VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLL 124 V+LG + + +++ A + ++ HP FN+ ++++D+ L+ Sbjct: 61 PVSKEHVTVYLGLHDV-RDKSGAVNSSAARVVLHPDFNIQ-----------NYNHDIALV 108 Query: 125 RLSKPADITDVVKPIALPT---KEPKPGSKCLASGWGS----------ITPTRWQKPDDL 171 +L +P + V P+ LP + P P L +GWG I+ D L Sbjct: 109 QLQEPVPLGPHVMPVCLPRLEPEGPAPHMLGLVAGWGISNPNVTVDEIISSGTRTLSDVL 168 Query: 172 QCVFITLLPNENCAKVYLQK-----VTDVMLCAGEMGGGKDTCRDDSGGPLI------CD 220 Q V + ++P+ C Y + VT+ M CAG GGKDTC DSGG + Sbjct: 169 QYVKLPVVPHAECKTSYESRSGNYSVTENMFCAGYYEGGKDTCLGDSGGAFVIFDDLSQR 228 Query: 221 GILQGTTSY-GPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 ++QG S+ GP CG V +YT + + W+ + M Sbjct: 229 WVVQGLVSWGGPEECGSKQVYGVYTKVSNYVDWVWEQMG 267 >4FXG-H nrPDB Length = 242 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 77/255 (30%), Positives = 109/255 (42%), Gaps = 38/255 (14%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ------YEVWLGKN 78 + GG K PWQV + G LL NWVLTAAH +Q ++ +G Sbjct: 1 IYGGQKAKPGDFPWQVLIL--GGTTAAGALLYDNWVLTAAHAVYEQKHDASALDIRMG-- 56 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 L + P F H G+ A F ND+ L++L+ I + P Sbjct: 57 TLKRLSPHYTQAWSEAVFIHEGYTHD----------AGFDNDIALIKLNNKVVINSNITP 106 Query: 139 IALPTKEPK----PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY------ 188 I LP KE + ASGWG R +L V I ++ ++ C Y Sbjct: 107 ICLPRKEAESFMRTDDIGTASGWGLTQ--RGFLARNLMYVDIPIVDHQKCTAAYEKPPYP 164 Query: 189 LQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPCGKPGVPAI 242 VT MLCAG GGKD+CR D+GG L+ + G S+G + CG+ G + Sbjct: 165 RGSVTANMLCAGLESGGKDSCRGDAGGALVFLDSETERWFVGGIVSWGSMNCGEAGQYGV 224 Query: 243 YTNLIKFNSWIKDTM 257 YT +I + WI++ + Sbjct: 225 YTKVINYIPWIENII 239 >1ELT-A nrPDB Length = 236 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 74/248 (29%), Positives = 109/248 (43%), Gaps = 27/248 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVD--QYEVWLGKN 78 VVGG + NS PWQ+++ Y+ H CGG L+ + WV+TAAHC + V LG++ Sbjct: 1 VVGGRVAQPNSWPWQISLQYKSGSSYYHTCGGSLIRQGWVMTAAHCVDSARTWRVVLGEH 60 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 L E Q V+ F H G+N + D+ LLRL+ A + V+ Sbjct: 61 NLNTNEGKEQIMTVNSVFIHSGWNSDDVAG---------GYDIALLRLNTQASLNSAVQL 111 Query: 139 IALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQKVTD 194 ALP + C +GWG T D L+ ++ + + C+ + V Sbjct: 112 AALPPSNQILPNNNPCYITGWGKT-STGGPLSDSLKQAWLPSVDHATCSSSGWWGSTVKT 170 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICD----GILQGTTSY-GPVPCGKPGVPAIYTNLIKF 249 M+CAG G C DSGGPL C + G TS+ C P ++T + + Sbjct: 171 TMVCAGG--GANSGCNGDSGGPLNCQVNGSYYVHGVTSFVSSSGCNASKKPTVFTRVSAY 228 Query: 250 NSWIKDTM 257 SW+ M Sbjct: 229 ISWMNGIM 236 >4DJZ-B nrPDB Length = 251 Score = 227 bits (578), Expect = 5e-60, Method: Composition-based stats. Identities = 74/260 (28%), Positives = 115/260 (44%), Gaps = 42/260 (16%) Query: 25 VVGGFNCKKNSQPWQVAVYY-QKEHICGGVLLDRNWVLTAAHCY---------------- 67 + G +K + PW + + + CGG LL +W++TAAHC Sbjct: 1 IFNGRPAQKGTTPWIAMLSHLNGQPFCGGSLLGSSWIVTAAHCLHQSLDPKDPTLRDSDL 60 Query: 68 --VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLR 125 +++ LGK+ + + + QH V + HP ++ + F ND+ L+ Sbjct: 61 LSPSDFKIILGKHWRLRSDENEQHLGVKHTTLHPQYDPNT-----------FENDVALVE 109 Query: 126 LSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 L + + V PI LP + G+ + SGWG R P+ L + I ++ + C Sbjct: 110 LLESPVLNAFVMPICLPEGPQQEGAMVIVSGWGKQFLQR--FPETLMEIEIPIVDHSTCQ 167 Query: 186 KVY---LQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC------DGILQGTTSYGPVPCGK 236 K Y +KVT M+CAGE GGKD C DSGGP++ L GT S+G CGK Sbjct: 168 KAYAPLKKKVTRDMICAGEKEGGKDACAGDSGGPMVTLNRERGQWYLVGTVSWGD-DCGK 226 Query: 237 PGVPAIYTNLIKFNSWIKDT 256 +Y+ + WI+ Sbjct: 227 KDRYGVYSYIHHNKDWIQRV 246 >4BXW-A nrPDB Length = 423 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 70/262 (26%), Positives = 106/262 (40%), Gaps = 17/262 (6%) Query: 11 SLGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYY-QKEHICGGVLLDRNWVLTAAHCY-- 67 +L P R+V G +CK PWQ A+ ++ CGG +L +VLTAAHC Sbjct: 156 TLLKKSDNPSPDIRIVNGMDCKLGECPWQAALVDEKEGVFCGGTILSPIYVLTAAHCINE 215 Query: 68 VDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 + V +G+ + E V K + H F + D+ D+ ++++ Sbjct: 216 TETISVVVGEIDKSRIETGPL-LSVDKIYVHKKFVPPQKAYKFDLAAYDY--DIAIIQMK 272 Query: 128 KPADITDVVKPIALPTKEPKPG-----SKCLASGWGSITPTRWQKPDDLQCVFITLLPNE 182 P ++ V P LPT + + SG+G I + K L+ + + + Sbjct: 273 TPIQFSENVVPACLPTADFANQVLMKQDFGIVSGFGRIVE-KGPKSKTLKVLKVPYVDRH 331 Query: 183 NCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPG 238 C +T M CAG +D C+ DSGGP + G S G C + G Sbjct: 332 TCMVSSETPITPNMFCAGYDTLPRDACQGDSGGPHTTVYRDTHFITGIVSSGE-GCARNG 390 Query: 239 VPAIYTNLIKFNSWIKDTMMKN 260 YT L KF WIK M + Sbjct: 391 KYGNYTKLSKFIPWIKRIMRQK 412 >1FON-A nrPDB Length = 240 Score = 225 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 75/252 (29%), Positives = 112/252 (44%), Gaps = 30/252 (11%) Query: 27 GGFNCKKNSQPWQVAVYYQK----EHICGGVLLDRNWVLTAAHCYVDQ--YEVWLGKNKL 80 G + S WQV++ Y+K H CGG L+ +WV+TA HC Y+V LG+ Sbjct: 1 NGEDAVPYSWSWQVSLQYEKDGAFHHTCGGSLIAPDWVVTAGHCISTSRTYQVVLGEYDR 60 Query: 81 FQEEPSAQHRLVSK--SFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 E S Q ++ F HP +N + + ND+ L++LS+ A + D V+ Sbjct: 61 SVLEGSEQVIPINAGDLFVHPLWNSNCVAC---------GNDIALVKLSRSAQLGDKVQL 111 Query: 139 IALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAK--VYLQKVTD 194 LP + C SGWG + T PD LQ + + E+C++ + V Sbjct: 112 ANLPPAGDILPNEAPCYISGWGRLY-TGGPLPDKLQQALLPTVDYEHCSQWDWWGITVKK 170 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLIC-----DGILQGTTSYGP-VPCGKPGVPAIYTNLIK 248 M+CAG + C DSGGPL C + G TS+ C P ++T + Sbjct: 171 TMVCAGGDT--RSGCNGDSGGPLNCPAADGSWQVHGVTSFVSAFGCNTIKKPTVFTRVSA 228 Query: 249 FNSWIKDTMMKN 260 F WI +T+ N Sbjct: 229 FIDWIDETIASN 240 >2ZKS-A nrPDB Length = 240 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 64/246 (26%), Positives = 112/246 (45%), Gaps = 23/246 (9%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ---YEVWLGKNKLF 81 ++GG +S+P+ ++ H+CGGVL+ WVLTAAHC + + LG + L Sbjct: 1 IIGGREVIPHSRPYMASLQRNGSHLCGGVLVHPKWVLTAAHCLAQRMAQLRLVLGLHTL- 59 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + + + HP + P NDL LL+L + ++P+AL Sbjct: 60 --DSPGLTFHIKAAIQHPRYK----------PVPALENDLALLQLDGKVKPSRTIRPLAL 107 Query: 142 PTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC--AKVYLQKVTDVML 197 P+K G++C +GWG +T + L+ + + +L C ++ + ++ M+ Sbjct: 108 PSKRQVVAAGTRCSMAGWG-LTHQGGRLSRVLRELDLQVLDTRMCNNSRFWNGSLSPSMV 166 Query: 198 CAGEMGGGKDTCRDDSGGPLICDG--ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 C + C+ DSGGPL+C +L G S+ C P + T + + SWI+ Sbjct: 167 CLAADSKDQAPCKGDSGGPLVCGKGRVLAGVLSFSSRVCTDIFKPPVATAVAPYVSWIRK 226 Query: 256 TMMKNA 261 ++A Sbjct: 227 VTGRSA 232 >5O32-I nrPDB Length = 244 Score = 217 bits (554), Expect = 3e-57, Method: Composition-based stats. Identities = 70/246 (28%), Positives = 105/246 (42%), Gaps = 33/246 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV----DQYEVWLGKNKL 80 +VGG + PWQVA+ CGG+ + W+LTAAHC +Y++W Sbjct: 1 IVGGKRAQLGDLPWQVAIKDASGITCGGIYIGGCWILTAAHCLRASKTHRYQIWTTVVDW 60 Query: 81 FQEE-PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 + V + H +N + ND+ L+ + K + D P Sbjct: 61 IHPDLKRIVIEYVDRIIFHENYN-----------AGTYQNDIALIEMKKDGNKKDCELPR 109 Query: 140 ALPTKEP------KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT 193 ++P P +P C+ SGWG ++ LQ + L+ N C+K Y + Sbjct: 110 SIPACVPWSPYLFQPNDTCIVSGWGREKDN--ERVFSLQWGEVKLISN--CSKFYGNRFY 165 Query: 194 D-VMLCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSYGPVPCGKPGVPAIYTNLI 247 + M CAG G D C+ DSGGPL+C + G S+G CGKP P +YT + Sbjct: 166 EKEMECAGTYDGSIDACKGDSGGPLVCMDANNVTYVWGVVSWGEN-CGKPEFPGVYTKVA 224 Query: 248 KFNSWI 253 + WI Sbjct: 225 NYFDWI 230 >5UBM-A nrPDB Length = 252 Score = 214 bits (546), Expect = 3e-56, Method: Composition-based stats. Identities = 72/261 (27%), Positives = 107/261 (40%), Gaps = 37/261 (14%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYE--VWLGKNKLF 81 R++GG + + PWQV GG L++ WVLTAAH E +++G + Sbjct: 1 RIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNREPTMYVGSTSVQ 57 Query: 82 QEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + F HPG+ +L+ +F ND+ L+RL P + V PI Sbjct: 58 TSRLAKSKMLTPEHVFIHPGWK----LLEVPEGRTNFDNDIALVRLKDPVKMGPTVSPIC 113 Query: 141 LP----TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK----- 191 LP G L SGWG + + L+ + + P C +V ++K Sbjct: 114 LPGTSSDYNLMDGDLGLISGWGRT--EKRDRAVRLKAARLPVAPLRKCKEVKVEKPTADA 171 Query: 192 ----VTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTSYGPVPCGKPGVP 240 T M+CAG G D+C+ DSGG G S+GP CG Sbjct: 172 EAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVSWGPQ-CGT---Y 226 Query: 241 AIYTNLIKFNSWIKDTMMKNA 261 +YT + + WI TM +N+ Sbjct: 227 GLYTRVKNYVDWIMKTMQENS 247 >1ELV-A nrPDB Length = 333 Score = 214 bits (545), Expect = 3e-56, Method: Composition-based stats. Identities = 73/273 (26%), Positives = 108/273 (39%), Gaps = 37/273 (13%) Query: 12 LGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQY 71 G + R++GG + + PWQV GG L++ WVLTAAH Sbjct: 70 CGVPREPFEEKQRIIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNR 126 Query: 72 E--VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 E +++G + + F HPG+ +L +F ND+ L+RL Sbjct: 127 EPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWK----LLAVPEGRTNFDNDIALVRLKD 182 Query: 129 PADITDVVKPIALP----TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 P + V PI LP G L SGWG + + L+ + + P C Sbjct: 183 PVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRT--EKRDRAVRLKAARLPVAPLRKC 240 Query: 185 AKVYLQK---------VTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTS 228 +V ++K T M+CAG G D+C+ DSGG G S Sbjct: 241 KEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVS 299 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 +GP CG +YT + + WI TM +N+ Sbjct: 300 WGPQ-CGT---YGLYTRVKNYVDWIMKTMQENS 328 >1YM0-A nrPDB Length = 238 Score = 210 bits (535), Expect = 5e-55, Method: Composition-based stats. Identities = 68/251 (27%), Positives = 105/251 (41%), Gaps = 28/251 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE--HICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKN 78 +VGG + PWQV+V + H CGG +++ WV+ AAHC + + +G++ Sbjct: 1 IVGGIEARPYEFPWQVSVRRKSSDSHFCGGSIINDRWVVCAAHCMQGEAPALVSLVVGEH 60 Query: 79 KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 Q V F + ++ A ND+ +++ + V P Sbjct: 61 DSSAASTVRQTHDVDSIFVNENYDP-----------ATLENDVSVIKTAVAITFDINVGP 109 Query: 139 IALPT-KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY-LQKVTDVM 196 I P K SGWG+I P L+ V + + N C VY + D M Sbjct: 110 ICAPDPANDYVYRKSQCSGWGTINSGGVCCPAVLRYVTLNITTNAFCDAVYTSDTIYDDM 169 Query: 197 LCAGEMGG--GKDTCRDDSGGPLICDG-----ILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 +CA + G +D+C+ DSGGPL L G S+G + C G P +Y+ + Sbjct: 170 ICATDNTGMTDRDSCQGDSGGPLSVKDGSGIFSLVGIVSWG-IGCAS-GYPGVYSRVGFH 227 Query: 250 NSWIKDTMMKN 260 WI DT+ N Sbjct: 228 AGWITDTITNN 238 >5KWM-A nrPDB Length = 230 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 67/235 (28%), Positives = 102/235 (43%), Gaps = 27/235 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYY-QKEHICGGVLLDRNWVLTAAHCYVD----QYEVWLGKNK 79 +VGG + P+ VA+ + CGG L N V+TAAHC V V G+ Sbjct: 1 IVGGEDANVQDHPFTVALVTPDGQQFCGGTLAAPNKVVTAAHCTVGSQPADINVVSGRTV 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 + E + V+ + HP + A D+ +L L P PI Sbjct: 61 MSSNEGTVSK--VTNVWVHPEY-----------QDAAKGFDVSVLTLEAPVK----EAPI 103 Query: 140 ALPTKEPK---PGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM 196 L + P + GWG+ + Q+ D LQ + + ++ C + Y + D M Sbjct: 104 ELAKADDAGYAPDTAATILGWGNTSE-GGQQADHLQKATVPVNSDDTCKQAYGEYTPDAM 162 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNS 251 +CAG GG DTC+ DSGGP++ + L G TS+G C +PG P +Y + + Sbjct: 163 VCAGVPEGGVDTCQGDSGGPMVVNNKLIGVTSWGE-GCARPGKPGVYARVGAYYD 216 >1EQ9-A nrPDB Length = 222 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 75/241 (31%), Positives = 111/241 (46%), Gaps = 25/241 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV-----DQYEVWLGKNK 79 +VGG + P+QV++ H CG +LD N VLTAAHC ++ +V +G N Sbjct: 1 IVGGKDAPVGKYPYQVSLRLSGSHRCGASILDNNNVLTAAHCVDGLSNLNRLKVHVGTNY 60 Query: 80 LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPI 139 L S V + + ++ LL ND+ L+ L+ P D+V+PI Sbjct: 61 L---SESGDVYDVEDAVVNKNYDDFLLR-----------NDVALVHLTNPIKFNDLVQPI 106 Query: 140 ALPTKEPKPGS-KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 L T + S C +GWGS P+ LQ + + + P + C + +V D +C Sbjct: 107 KLSTNDEDLESNPCTLTGWGSTR-LGGNTPNALQEIELIVHPQKQCERD-QWRVIDSHIC 164 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G+ C DSGGPL+ +G G S+G PC G P +YT + F SWI + Sbjct: 165 T-LTKRGEGACHGDSGGPLVANGAQIGIVSFGS-PCAL-GEPDVYTRVSSFVSWINANLK 221 Query: 259 K 259 K Sbjct: 222 K 222 >4J1Y-A nrPDB Length = 397 Score = 208 bits (531), Expect = 1e-54, Method: Composition-based stats. Identities = 73/273 (26%), Positives = 109/273 (39%), Gaps = 37/273 (13%) Query: 12 LGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQY 71 G ++R +GG + + PWQV GG L++ WVLTAAH Sbjct: 134 CGVPREPFEEKARAIGGSDADIKNFPWQVFF---DNPWAGGALINEYWVLTAAHVVEGNR 190 Query: 72 E--VWLGKNKLFQEEPSAQH-RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 E +++G + + F HPG+ +L+ +F ND+ L+RL Sbjct: 191 EPTMYVGSTSVQTSRLAKSKMLTPEHVFIHPGWK----LLEVPEGRTNFDNDIALVRLKD 246 Query: 129 PADITDVVKPIALP----TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 P + V PI LP G L SGWG + + L+ + + P C Sbjct: 247 PVKMGPTVSPICLPGTSSDYNLMDGDLGLISGWGRT--EKRDRAVRLKAARLPVAPLRKC 304 Query: 185 AKVYLQK---------VTDVMLCAGEMGGGKDTCRDDSGGPLICDG-------ILQGTTS 228 +V ++K T M+CAG G D+C+ DSGG G S Sbjct: 305 KEVKVEKPTADAEAYVFTPNMICAGG-EKGMDSCKGDSGGAFAVQDPNDKTKFYAAGLVS 363 Query: 229 YGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 +GP CG +YT + + WI TM +N+ Sbjct: 364 WGPQ-CGT---YGLYTRVKNYVDWIMKTMQENS 392 >2B9L-A nrPDB Length = 394 Score = 207 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 71/281 (25%), Positives = 111/281 (39%), Gaps = 46/281 (16%) Query: 14 GIDAAPPLQSRVVGGF-NCKKNSQPWQVAVYY--------QKEHICGGVLLDRNWVLTAA 64 GI L ++ G + PW VAV +++ +CGG L+ + VLT A Sbjct: 119 GIRNERGLDFKITGQTNEAEYGEFPWMVAVLKANVIPGSGEEQLVCGGSLIAPSVVLTGA 178 Query: 65 HCYV------DQYEVWLGKNKLFQEEP--SAQHRLVSKSFPHPGFNMSLLMLQTIPPGAD 116 HC D ++ G+ E+ Q R + + H FN ++ Sbjct: 179 HCVNSYQSNLDAIKIRAGEWDTLTEKERLPYQERKIRQVIIHSNFNPKTVV--------- 229 Query: 117 FSNDLMLLRLSKPADITDVVKPIALPTKEP-KPGSKCLASGWGSIT-PTRWQKPDDLQCV 174 ND+ LL L +P D + I LP + ++C ASGWG +R + + L+ + Sbjct: 230 --NDVALLLLDRPLVQADNIGTICLPQQSQIFDSTECFASGWGKKEFGSRHRYSNILKKI 287 Query: 175 FITLLPNENCAKVYLQK-------VTDVMLCAGEMGGGKDTCRDDSGGPLICDG------ 221 + + + C + +CAG GKDTC D G PL C Sbjct: 288 QLPTVDRDKCQADLRNTRLGLKFVLDQTFVCAGGEQ-GKDTCTGDGGSPLFCPDPRNPSR 346 Query: 222 -ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKNA 261 + G ++G + CG VP +Y N+ F +WI M Sbjct: 347 YMQMGIVAWG-IGCGDENVPGVYANVAHFRNWIDQEMQAKG 386 >1PPF-E nrPDB Length = 218 Score = 207 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 61/240 (25%), Positives = 107/240 (44%), Gaps = 28/240 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVW----LGKNKL 80 +VGG + ++ P+ V++ + H CG L+ N+V++AAHC + LG + L Sbjct: 1 IVGGRRARPHAWPFMVSLQLRGGHFCGATLIAPNFVMSAAHCVANVNVRAVRVVLGAHNL 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + EP+ Q V + F + + ND+++L+L+ A I V+ Sbjct: 61 SRREPTRQVFAVQRIF------------ENGYDPVNLLNDIVILQLNGSATINANVQVAQ 108 Query: 141 LPTKEPKPGS--KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 LP + + G+ +CLA GWG + R LQ + +T++ C + +C Sbjct: 109 LPAQGRRLGNGVQCLAMGWGLLGRNRG-IASVLQELNVTVVT-SLCRR--------SNVC 158 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G C DSG PL+C+G++ G S+ C P + + +F +WI + Sbjct: 159 TLVRGRQAGVCFGDSGSPLVCNGLIHGIASFVRGGCASGLYPDAFAPVAQFVNWIDSIIQ 218 >1GPZ-A nrPDB Length = 399 Score = 207 bits (526), Expect = 6e-54, Method: Composition-based stats. Identities = 64/265 (24%), Positives = 100/265 (37%), Gaps = 41/265 (15%) Query: 19 PPLQSR--VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD------- 69 P++ R ++GG K + PWQV GG LL W+LTAAH Sbjct: 150 NPVEQRQQIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQS 207 Query: 70 --QYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLS 127 +V+LG + + H + + HP + +F D+ LL L Sbjct: 208 NASLDVFLGHTNVEELMKLGNH-PIRRVSVHPDYRQD--------ESYNFEGDIALLELE 258 Query: 128 KPADITDVVKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 + + PI LP + G SG+G + + DL+ V + + + C Sbjct: 259 NSVTLGPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACE 315 Query: 186 KVYLQK-----VTDVMLCAGEMGGGKDTCRDDSGG------PLICDGILQGTTSYGPVPC 234 K + M CAG +D C+ DSGG P + G S+G + C Sbjct: 316 NWLRGKNRMDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG-IGC 374 Query: 235 GKPGVPAIYTNLIKFNSWIKDTMMK 259 + YT ++ + WIK M + Sbjct: 375 SRG--YGFYTKVLNYVDWIKKEMEE 397 >2QY0-B nrPDB Length = 242 Score = 206 bits (524), Expect = 9e-54, Method: Composition-based stats. Identities = 62/257 (24%), Positives = 96/257 (37%), Gaps = 39/257 (15%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD---------QYEVWL 75 ++GG K + PWQV GG LL W+LTAAH +V+L Sbjct: 1 IIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLDVFL 58 Query: 76 GKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV 135 G + + H + + HP + +F D+ LL L + Sbjct: 59 GHTNVEELMKLGNH-PIRRVSVHPDYRQD--------ESYNFEGDIALLELENSVTLGPN 109 Query: 136 VKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-- 191 + PI LP + G SG+G + + DL+ V + + + C K Sbjct: 110 LLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRGKNR 166 Query: 192 ---VTDVMLCAGEMGGGKDTCRDDSGG------PLICDGILQGTTSYGPVPCGKPGVPAI 242 + M CAG +D C+ DSGG P + G S+G + C + Sbjct: 167 MDVFSQNMFCAGHPSLKQDACQGDSGGVFAVRDPNTDRWVATGIVSWG-IGCSRG--YGF 223 Query: 243 YTNLIKFNSWIKDTMMK 259 YT ++ + WIK M + Sbjct: 224 YTKVLNYVDWIKKEMEE 240 >1MD7-A nrPDB Length = 328 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 62/258 (24%), Positives = 97/258 (37%), Gaps = 39/258 (15%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD---------QYE 72 + R++GG K + PWQV GG LL W+LTAAH + Sbjct: 87 RQRIIGGQKAKMGNFPWQVFTNIHGRG--GGALLGDRWILTAAHTLYPKEHEAQSNASLD 144 Query: 73 VWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADI 132 V+LG + + H + + HP + +F D+ LL L + Sbjct: 145 VFLGHTNVEELMKLGNH-PIRRVSVHPDYRQD--------ESYNFEGDIALLELENSVTL 195 Query: 133 TDVVKPIALPTKEP--KPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQ 190 + PI LP + G SG+G + + DL+ V + + + C Sbjct: 196 GPNLLPICLPDNDTFYDLGLMGYVSGFGVMEE---KIAHDLRFVRLPVANPQACENWLRG 252 Query: 191 K-----VTDVMLCAGEMGGGKDTCRDDSGG------PLICDGILQGTTSYGPVPCGKPGV 239 K + M CAG +D C+ D+GG P + G S+G + C + Sbjct: 253 KNRMDVFSQNMFCAGHPSLKQDACQGDAGGVFAVRDPNTDRWVATGIVSWG-IGCSRG-- 309 Query: 240 PAIYTNLIKFNSWIKDTM 257 YT ++ + WIK M Sbjct: 310 YGFYTKVLNYVDWIKKEM 327 >2OLG-A nrPDB Length = 278 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 67/269 (24%), Positives = 115/269 (42%), Gaps = 47/269 (17%) Query: 24 RVVGGFNCKKNSQPWQVAVYYQK-----EHICGGVLLDRNWVLTAAHCYVDQY------- 71 +++ G + PW + Y+ + CGG L++ +++TAAHC + Sbjct: 22 KILNGDDTVPEEFPWTAMIGYKNSSNFEQFACGGSLINNRYIVTAAHCVAGRVLRVVGAL 81 Query: 72 -EVWLGKNKLFQEEPSAQHRLV-----------SKSFPHPGFNMSLLMLQTIPPGADFSN 119 +V LG+ + V ++ HP + + D + Sbjct: 82 NKVRLGEWNTATDPDCYGAVRVCVPDKPIDLGIEETIQHPDY---------VDGSKDRYH 132 Query: 120 DLMLLRLSKPADITDVVKPIALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFIT 177 D+ L+RL++ + T+ ++P+ LP +E + G + GWG Q Q + + Sbjct: 133 DIALIRLNRQVEFTNYIRPVCLPQPNEEVQVGQRLTVVGWGRTET--GQYSTIKQKLAVP 190 Query: 178 LLPNENCAKVYLQ---KVTDVMLCAGEMGGGKDTCRDDSGGPLICDG-----ILQGTTSY 229 ++ E CAK + +V LCAG KD+C DSGGPL+ + L+G S+ Sbjct: 191 VVHAEQCAKTFGAAGVRVRSSQLCAGG-EKAKDSCGGDSGGPLLAERANQQFFLEGLVSF 249 Query: 230 GPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G CG G P IYT + K+ WI+ + Sbjct: 250 GAT-CGTEGWPGIYTKVGKYRDWIEGNIR 277 >1AE5-A nrPDB Length = 225 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 64/241 (26%), Positives = 103/241 (42%), Gaps = 28/241 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQ----YEVWLGKNKL 80 +VGG + P+ ++ Q H CGG L+ +V+TAA C+ Q V LG L Sbjct: 1 IVGGRKARPRQFPFLASIQNQGRHFCGGALIHARFVMTAASCFQSQNPGVSTVVLGAYDL 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + E ++ S G++ + NDLMLL+L + A++T V + Sbjct: 61 RRRERQSRQTFSISSMSENGYDPQQNL-----------NDLMLLQLDREANLTSSVTILP 109 Query: 141 LP--TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC 198 LP + G++C +GWGS + + V +T+ P + C +C Sbjct: 110 LPLQNATVEAGTRCQVAGWGSQRS-GGRLSRFPRFVNVTVTPEDQCR--------PNNVC 160 Query: 199 AGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMM 258 G + C D G PL+C+G+ G S+ PCG+ P +T + F WI + Sbjct: 161 TGVLTRRGGICNGDGGTPLVCEGLAHGVASFSLGPCGRG--PDFFTRVALFRDWIDGVLN 218 Query: 259 K 259 Sbjct: 219 N 219 >2PKA-B nrPDB Length = 152 Score = 205 bits (522), Expect = 2e-53, Method: Composition-based stats. Identities = 86/150 (57%), Positives = 106/150 (70%), Gaps = 2/150 (1%) Query: 113 PGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPT--RWQKPDD 170 G D+S+DLMLLRL PA ITD VK + LPT+EP+ GS C ASGWGSI P ++ PD+ Sbjct: 2 DGKDYSHDLMLLRLQSPAKITDAVKVLELPTQEPELGSTCEASGWGSIEPGPDDFEFPDE 61 Query: 171 LQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYG 230 +QCV +TLL N CA + KVT+ MLCAG + GGKDTC DSGGPLIC+G+ QG TS+G Sbjct: 62 IQCVQLTLLQNTFCADAHPDKVTESMLCAGYLPGGKDTCMGDSGGPLICNGMWQGITSWG 121 Query: 231 PVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 PCG P+IYT LI + WI DT+ +N Sbjct: 122 HTPCGSANKPSIYTKLIFYLDWIDDTITEN 151 >4LK4-A nrPDB Length = 357 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 60/257 (23%), Positives = 103/257 (40%), Gaps = 30/257 (11%) Query: 15 IDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQK-----EHICGGVLLDRNWVLTAAHCYVD 69 +++ + SR++ G N P VA+ + CGG L +VLTAAHC+ Sbjct: 1 MESTADISSRIINGSNANSAEWPSIVALVKRGADAYQGQFCGGSFLGGRYVLTAAHCFDS 60 Query: 70 Q----YEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLR 125 + +V +G L K + H ++ S L+ ND+ ++ Sbjct: 61 RSAASVDVIIGAYDLNNSSQGE-RIAAQKIYRHLSYSPSNLL-----------NDIAIVE 108 Query: 126 LSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQK-PDDLQCVFITLLPNENC 184 L++ + + + + +GWG ++ + LQ V + L+ C Sbjct: 109 LAQTSSLPAITLAGPATRTSLPALTPLTVAGWGITVQSKPPQFTPILQEVDVDLVSQSLC 168 Query: 185 AKVYLQKVTD----VMLCAGEMGGGKDTCRDDSGGPLICD-GILQ-GTTSYGPVPCGKPG 238 V ++ CA + KD+C+ D+GGP++ G Q G S+G C K G Sbjct: 169 QIVMQHGISSDPNSTNFCAARLT--KDSCQGDAGGPIVVKTGREQLGIVSWGDEQCAKTG 226 Query: 239 VPAIYTNLIKFNSWIKD 255 +YTN+ F WI Sbjct: 227 TYGVYTNVSYFRDWITK 243 >4X0L-C nrPDB Length = 259 Score = 199 bits (506), Expect = 1e-51, Method: Composition-based stats. Identities = 55/274 (20%), Positives = 95/274 (34%), Gaps = 48/274 (17%) Query: 15 IDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVW 74 + A P+Q R++GG K S PWQ + G L++ W+LT A + Sbjct: 6 KNPANPVQ-RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSEN 64 Query: 75 LGKNKL----FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 + Q + K HP ++ D+ L++L + Sbjct: 65 ATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV---------------DIGLIKLKQKV 109 Query: 131 DITDVVKPIALPTKE-PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL 189 + + V PI LP+K+ + G SGWG ++ D L+ V + + + C + Y Sbjct: 110 SVNERVMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYE 167 Query: 190 QK-----------------VTDVMLCAGEMGGGKDTCRDDSGGPLICD------GILQGT 226 + + CAG +DTC D+G G Sbjct: 168 GSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGI 227 Query: 227 TSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 S+ C +Y + W++ T+ +N Sbjct: 228 LSF-DKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 259 >4WJG-C nrPDB Length = 315 Score = 198 bits (504), Expect = 2e-51, Method: Composition-based stats. Identities = 55/274 (20%), Positives = 95/274 (34%), Gaps = 48/274 (17%) Query: 15 IDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVW 74 + A P+Q R++GG K S PWQ + G L++ W+LT A + Sbjct: 62 KNPANPVQ-RILGGHLDAKGSFPWQAKMVSHHNLTTGATLINEQWLLTTAKNLFLNHSEN 120 Query: 75 LGKNKL----FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 + Q + K HP ++ D+ L++L + Sbjct: 121 ATAKDIAPTLTLYVGKKQLVEIEKVVLHPNYSQV---------------DIGLIKLKQKV 165 Query: 131 DITDVVKPIALPTKE-PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL 189 + + V PI LP+K+ + G SGWG ++ D L+ V + + + C + Y Sbjct: 166 SVNERVMPICLPSKDYAEVGRVGYVSGWGR--NANFKFTDHLKYVMLPVADQDQCIRHYE 223 Query: 190 QK-----------------VTDVMLCAGEMGGGKDTCRDDSGGPLICD------GILQGT 226 + + CAG +DTC D+G G Sbjct: 224 GSTVPEKKTPKSPVGVQPILNEHTFCAGMSKYQEDTCYGDAGSAFAVHDLEEDTWYATGI 283 Query: 227 TSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 S+ C +Y + W++ T+ +N Sbjct: 284 LSF-DKSCAVAE-YGVYVKVTSIQDWVQKTIAEN 315 >1PQ7-A nrPDB Length = 224 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 68/234 (29%), Positives = 103/234 (44%), Gaps = 17/234 (7%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 +VGG + P+ V++ CGG LL+ N VLTAAHC + Sbjct: 1 IVGGTSASAGDFPFIVSISRNGGPWCGGSLLNANTVLTAAHCVSGYAQ------------ 48 Query: 85 PSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVV--KPIALP 142 Q R S S G SL ++ P + +NDL +L+LS + +A Sbjct: 49 SGFQIRAGSLSRTSGGITSSLSSVRVHPSYSGNNNDLAILKLSTSIPSGGNIGYARLAAS 108 Query: 143 TKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-QKVTDVMLCAGE 201 +P GS +GWG+ + P +L V + ++ C Y +T+ M CAG Sbjct: 109 GSDPVAGSSATVAGWGATSEGGSSTPVNLLKVTVPIVSRATCRAQYGTSAITNQMFCAGV 168 Query: 202 MGGGKDTCRDDSGGPLI-CDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIK 254 GGKD+C+ DSGGP++ L G S+G C +P +Y ++ S+I Sbjct: 169 SSGGKDSCQGDSGGPIVDSSNTLIGAVSWGN-GCARPNYSGVYASVGALRSFID 221 >4F4O-C nrPDB Length = 347 Score = 195 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 57/283 (20%), Positives = 90/283 (31%), Gaps = 59/283 (20%) Query: 12 LGGIDAAPPLQSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQY 71 G R++GG K S PWQ + G L++ W+LT A Sbjct: 90 CGKPKNPVDQVQRIMGGSLDAKGSFPWQAKMISHHNLTSGATLINEQWLLTTA------K 143 Query: 72 EVWLGKNK----------LFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDL 121 + LG L Q + K HP + + D+ Sbjct: 144 NLRLGHKNDTKAKDIAPTLRLYVGKKQEVEIEKVIFHPD---------------NSTVDI 188 Query: 122 MLLRLSKPADITDVVKPIALPTKE-PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLP 180 L++L + + + V PI LP+K+ G SGWG + L+ V + + Sbjct: 189 GLIKLKQKVPVNERVMPICLPSKDYVNVGLVGYVSGWGR--NANLNFTEHLKYVMLPVAD 246 Query: 181 NENCAKVYLQK-----------------VTDVMLCAGEMGGGKDTCRDDSGGPLICD--- 220 E C + Y + + CAG +DTC D+G Sbjct: 247 QEKCVQYYEGSTVPEKKTPKSPVGVQPILNEHTFCAGLSKYQEDTCYGDAGSAFAVHDKD 306 Query: 221 ---GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 G S+ C + +Y + WI+ T+ N Sbjct: 307 DDTWYAAGILSF-DKSC-RTAEYGVYVRVTSILDWIQTTIADN 347 >6BQM-A nrPDB Length = 506 Score = 195 bits (496), Expect = 2e-50, Method: Composition-based stats. Identities = 69/258 (26%), Positives = 102/258 (39%), Gaps = 37/258 (14%) Query: 20 PLQSRVVGGFNCKKNSQPWQVAVYYQKEH--ICGGVLLDRNWVLTAAHCYVD----QYEV 73 + SR++GG P+ VA+ + CGG L +VLTAAHC + +V Sbjct: 6 GVSSRIIGGEQATAGEWPYMVALTARNSSHVFCGGSYLGGRYVLTAAHCVDKEDPAKGDV 65 Query: 74 WLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK-PADI 132 LG + +A+ V + + H + A ND+ +L L + P Sbjct: 66 LLGAFDMNDVN-TAERIHVRQIYVHNSY-----------ITASMGNDIAVLELERDPLPR 113 Query: 133 TDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPD---DLQCVFITLLPNENCA---- 185 V + E S G+G+ +K D L V + +P C Sbjct: 114 RSVQISDSSDFNELTKDSPMTVIGFGNRKEVDGEKSDPATILHQVQVPFVPLPECKTKGS 173 Query: 186 ----KVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTTSYGPVPCGKP 237 K ++T+ CAG GKD C D+GGP+ D G S+G CG+ Sbjct: 174 DQDAKNNYSQLTNNAFCAGSF--GKDACSGDAGGPIFFDSNNGRKQMGVVSWGD-GCGRA 230 Query: 238 GVPAIYTNLIKFNSWIKD 255 P +YTNL FN W+ D Sbjct: 231 NSPGVYTNLSVFNDWLDD 248 >2HLC-A nrPDB Length = 230 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 60/243 (24%), Positives = 97/243 (39%), Gaps = 29/243 (11%) Query: 25 VVGGFNCKKNSQPWQV----AVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKL 80 ++ G+ P+Q + Q+ CGG L+D W+LTAAHC D V + Sbjct: 1 IINGYEAYTGLFPYQAGLDITLQDQRRVWCGGSLIDNKWILTAAHCVHDAVSVVVYLGSA 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 Q E + H FN + ND+ L+++ + TD ++PI Sbjct: 61 VQYE-GEAVVNSERIISHSMFNPDT-----------YLNDVALIKIPH-VEYTDNIQPIR 107 Query: 141 LPTKEPKPGSK----CLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY-LQKVTDV 195 LP+ E SGWG LQ + ++ N+ CA+ Y + + Sbjct: 108 LPSGEELNNKFENIWATVSGWGQSNTDTV----ILQYTYNLVIDNDRCAQEYPPGIIVES 163 Query: 196 MLCAGEMGGGKDTCRDDSGGPLICDG--ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 +C G+ GK C DSGGP + +L G S+ + G P ++ + + WI Sbjct: 164 TIC-GDTSDGKSPCFGDSGGPFVLSDKNLLIGVVSFVSGAGCESGKPVGFSRVTSYMDWI 222 Query: 254 KDT 256 + Sbjct: 223 QQN 225 >1SI5-H nrPDB Length = 240 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 70/247 (28%), Positives = 106/247 (42%), Gaps = 35/247 (14%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVD----QYEVWLGKNKL 80 VV G + N W V++ Y+ +HICGG L+ +WVLTA C+ YE WLG + + Sbjct: 1 VVNGIPTRTNIG-WMVSLRYRNKHICGGSLIKESWVLTARQCFPSRDLKDYEAWLGIHDV 59 Query: 81 --FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKP 138 +E Q VS+ P +DL+L++L++PA + D V Sbjct: 60 HGRGDEKCKQVLNVSQLVYGPE-----------------GSDLVLMKLARPAVLDDFVST 102 Query: 139 IALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT--D 194 I LP + C GWG + L+ + ++ NE C++ + KVT + Sbjct: 103 IDLPNYGSTIPEKTSCSVYGWGYTGLINYDG--LLRVAHLYIMGNEKCSQHHRGKVTLNE 160 Query: 195 VMLCAGEMGGGKDTCRDDSGGPLICDGILQ----GTTSYGPVPCGKPGVPAIYTNLIKFN 250 +CAG G C D GGPL+C+ G G C P P I+ + + Sbjct: 161 SEICAGAEKIGSGPCEGDYGGPLVCEQHKMRMVLGVIVPGR-GCAIPNRPGIFVRVAYYA 219 Query: 251 SWIKDTM 257 WI + Sbjct: 220 KWIHKII 226 >2ASU-B nrPDB Length = 234 Score = 191 bits (486), Expect = 2e-49, Method: Composition-based stats. Identities = 70/249 (28%), Positives = 101/249 (40%), Gaps = 38/249 (15%) Query: 25 VVGGFNCKKNSQPWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYVD------QYEVWLGK 77 VVGG + PW V++ Q +H CGG L+ W+LTA C+ YEVWLG Sbjct: 1 VVGGH---PGNSPWTVSLRNRQGQHFCGGSLVKEQWILTARQCFSSCHMPLTGYEVWLGT 57 Query: 78 N--KLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDV 135 EPS Q V+K P + L+LL+L + + Sbjct: 58 LFQNPQHGEPSLQRVPVAKMVCGPSGSQ-----------------LVLLKLERSVTLNQR 100 Query: 136 VKPIALPTK--EPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVT 193 V I LP + PG+KC +GWG T L + ++ N+ C + +V Sbjct: 101 VALICLPPEWYVVPPGTKCEIAGWGETKGTGNDT--VLNVALLNVISNQECNIKHRGRVR 158 Query: 194 DVMLCAGEMGGGKDTCRDDSGGPLIC----DGILQGTTSYGPVPCGKPGVPAIYTNLIKF 249 + +C + C D GGPL C +L+G V C + PA++T + F Sbjct: 159 ESEMCTEGLLAPVGACEGDYGGPLACFTHNSWVLEGIIIPNRV-CARSRWPAVFTRVSVF 217 Query: 250 NSWIKDTMM 258 WI M Sbjct: 218 VDWIHKVMR 226 >3I77-A nrPDB Length = 230 Score = 191 bits (485), Expect = 3e-49, Method: Composition-based stats. Identities = 66/242 (27%), Positives = 100/242 (41%), Gaps = 28/242 (11%) Query: 25 VVGGFNCKKNSQPWQV-AVYYQKEHICGGVLLDRNWVLTAAHCYV---DQYEVWLGKNKL 80 VVGG + P+ V + + E CGG L ++ VLTAAHC + + + Sbjct: 1 VVGGTRAAQGEFPFMVRLINEENEGFCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVV 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIA 140 + SA +K PGF + D L++L++P IA Sbjct: 61 DLQSSSAVKVRSTKVLQAPGFTK-----------ETYGKDWALIKLAQPI--NQPTLKIA 107 Query: 141 LPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTDVMLCA 199 T + G+ +GWG+ Q+ L+ + + + C V + M+CA Sbjct: 108 TTTAYNQ-GTF-TVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSSSSFILVANEMICA 164 Query: 200 GEMG-GGKDTCRDDSGGPLI-----CDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWI 253 G GG DTC+ DSGGP+ + I G S+G C +PG P +YT + F S I Sbjct: 165 GYPDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWG-YGCARPGYPGVYTEVSTFASAI 223 Query: 254 KD 255 Sbjct: 224 AS 225 >2FMJ-A nrPDB Length = 222 Score = 187 bits (476), Expect = 3e-48, Method: Composition-based stats. Identities = 63/240 (26%), Positives = 98/240 (40%), Gaps = 32/240 (13%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV---DQYEVWLGKNKLF 81 VVGG + P+ V + CGG L ++ VLTAAHC + + + Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + SA +K PG+N + D L++L++P IA Sbjct: 57 LQSSSAVKVRSTKVLQAPGYNGT-------------GKDWALIKLAQPI--NQPTLKIAT 101 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTDVMLCAG 200 T + G+ +GWG+ Q+ L+ + + + C Y + V + +CAG Sbjct: 102 TTAYNQ-GTF-TVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSAYGNELVANEEICAG 158 Query: 201 EMGGGKDTCRDDSGGPLI-----CDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 GG DTC+ DSGGP+ + I G S+G C + G +YT + F S I Sbjct: 159 YDTGGVDTCQGDSGGPMFRKDNADEWIQVGIVSWGE-GCARKGKYGVYTEVSTFASAIAS 217 >3BEU-A nrPDB Length = 224 Score = 187 bits (475), Expect = 5e-48, Method: Composition-based stats. Identities = 60/240 (25%), Positives = 95/240 (39%), Gaps = 30/240 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYV---DQYEVWLGKNKLF 81 VVGG + P+ V + CGG L ++ VLTAAHC + + + Sbjct: 1 VVGGTRAAQGEFPFMVRL----SMGCGGALYAQDIVLTAAHCVSGSGNNTSITATGGVVD 56 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + SA +K PGF + D L++L++P IA Sbjct: 57 LQSSSAVKVRSTKVLQAPGFTK-----------ETYGKDWALIKLAQPI--NQPTLKIAT 103 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQK-VTDVMLCAG 200 T + G+ +GWG+ Q+ L+ + + + C V + M+CAG Sbjct: 104 TTAYNQ-GTF-TVAGWGANREGGSQQRYLLK-ANVPFVSDAACRSSSSFILVANEMICAG 160 Query: 201 EMGGGKDTCRDDSGGPLI-----CDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKD 255 +DTC+ DSGGP+ + + G S+G C + G +YT + F S I Sbjct: 161 YDTKQEDTCQGDSGGPMFRKDNADEWVQVGIVSWGE-GCARKGKYGVYTEVSTFASAIAS 219 >5XW8-A nrPDB Length = 133 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 50/140 (35%), Positives = 76/140 (54%), Gaps = 12/140 (8%) Query: 22 QSRVVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLF 81 ++VGG+ C NS P+QV++ H CGG L++ WV++AAHCY + +V LG++ + Sbjct: 6 DDKIVGGYTCAANSIPYQVSLN-SGSHFCGGSLINSQWVVSAAHCYKSRIQVRLGEHNID 64 Query: 82 QEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 E + Q +K HP FN G ND+ML++LS PA + V ++L Sbjct: 65 VLEGNEQFINAAKIITHPNFN-----------GNTLDNDIMLIKLSSPATLNSRVATVSL 113 Query: 142 PTKEPKPGSKCLASGWGSIT 161 P G++CL SGWG+ Sbjct: 114 PRSCAAAGTECLISGWGNTK 133 >3H7T-A nrPDB Length = 235 Score = 173 bits (440), Expect = 5e-44, Method: Composition-based stats. Identities = 57/249 (22%), Positives = 97/249 (38%), Gaps = 31/249 (12%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCY----VDQYEVWLGKNKL 80 ++GG +PW V V ++ CGG +L N+V+TAA C + G + Sbjct: 1 IIGGKKSDITKEPWAVGVLVDEKPFCGGSILTANFVITAAQCVDGTKPSDISIHYGSSYR 60 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITD-VVKPI 139 + S + + HP N+ ++ P + D K I Sbjct: 61 TTKGTSVMAKKIYIVRYHP---------------LTMQNNYAVIETEMPIKLDDKTTKKI 105 Query: 140 ALPT--KEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYL-----QKV 192 LP+ +P+P + L SGWGS + DL T++ ++C + Y + + Sbjct: 106 ELPSLLYDPEPDTSVLVSGWGSTNFKSLEYSGDLMEANFTVVDRKSCEEQYKQIEADKYI 165 Query: 193 TDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSY-GPVPCGKPGVPAIYTNLIKFNS 251 D + CAG D+G P + +G L G SY +P P+++ + + Sbjct: 166 YDGVFCAGGEYDETYIGYGDAGDPAVQNGTLVGVASYISSMP---SEFPSVFLRVGYYVL 222 Query: 252 WIKDTMMKN 260 IKD + Sbjct: 223 DIKDIISGK 231 >1M9U-A nrPDB Length = 241 Score = 169 bits (429), Expect = 1e-42, Method: Composition-based stats. Identities = 64/251 (25%), Positives = 94/251 (37%), Gaps = 30/251 (11%) Query: 25 VVGGFNCKKNSQPWQVAVYYQK---EHICGGVLLDRNWVLTAAHCY----VDQYEVWLGK 77 V+GG N PWQ++ Q H CG LL L+A+HC + V G Sbjct: 1 VIGGTNASPGEFPWQLSQQRQSGSWSHSCGASLLSSTSALSASHCVDGVLPNNIRVIAGL 60 Query: 78 NKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVK 137 + + Q V H + A +SND+ +L L+ + ++ Sbjct: 61 WQQSDTSGT-QTANVDSYTMHENYGAGT---------ASYSNDIAILHLATSISLGGNIQ 110 Query: 138 PIALPTKE--PKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVY----LQK 191 LP G+ C+ SGWG T PD LQ I ++ C Sbjct: 111 AAVLPANNNNDYAGTTCVISGWGRTDGTN-NLPDILQKSSIPVITTAQCTAAMVGVGGAN 169 Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICDG---ILQGTTSYGP---VPCGKPGVPAIYTN 245 + D +C + G C DSGGPL C + G TS+ + P P++YT Sbjct: 170 IWDNHICVQDPAGNTGACNGDSGGPLNCPDGGTRVVGVTSWVVSSGLGACLPDYPSVYTR 229 Query: 246 LIKFNSWIKDT 256 + + WI D Sbjct: 230 VSAYLGWIGDN 240 >3H7O-A nrPDB Length = 228 Score = 166 bits (421), Expect = 9e-42, Method: Composition-based stats. Identities = 68/244 (27%), Positives = 103/244 (42%), Gaps = 27/244 (11%) Query: 27 GGFNCKKNSQPWQVAVYY---QKEHICGGVLLDRNWVLTAAHCYVDQYE---VWLGKNKL 80 GG PW VAV ++ CGG +L + +VLTAAHC DQ V ++ Sbjct: 2 GGEKTDIKQVPWTVAVRTYPGEESLTCGGAILSQWFVLTAAHCVFDQKPETIVIQYESTN 61 Query: 81 FQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITD-VVKPI 139 E+P VS + + ND+ +L LS+P + KP Sbjct: 62 LWEDPGKSDPYVSHVYL------------SFYRQETMENDIAILELSRPLKLDGLKSKPA 109 Query: 140 ALPTKEPKP--GSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVM- 196 LP E +P GS L SG+G T K DL+ +T++ + C Y + Sbjct: 110 KLPDIEFRPKTGSDVLVSGYGD-GQTMDPKDHDLKSAQLTVVDLDECRTKYGPIFLSLQV 168 Query: 197 LCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDT 256 CA ++G ++ D+G P + L G +Y P G P ++T + + SWI+D Sbjct: 169 FCAQKVGVSLES--GDAGDPTVQQDTLVGVAAY--FPKRPEGAPEVFTKVGSYVSWIQDI 224 Query: 257 MMKN 260 + K Sbjct: 225 IKKK 228 >1AKS-B nrPDB Length = 98 Score = 150 bits (379), Expect = 5e-37, Method: Composition-based stats. Identities = 37/99 (37%), Positives = 58/99 (58%), Gaps = 1/99 (1%) Query: 162 PTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG 221 + P LQC+ +L N +C Y ++T M+C G + GGKD+C+ DSGGP++C+G Sbjct: 1 SSGSSYPSLLQCLKAPVLSNSSCKSSYPGQITGNMICVGFLQGGKDSCQGDSGGPVVCNG 60 Query: 222 ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 LQG S+G C + P +YT + + +WI+ T+ N Sbjct: 61 QLQGIVSWG-YGCAQKNKPGVYTKVCNYVNWIQQTIAAN 98 >1RIW-B nrPDB Length = 147 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 42/157 (26%), Positives = 73/157 (46%), Gaps = 28/157 (17%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + + ++ K + HP +N + D+ L++L KP Sbjct: 61 VRIGKHSRTRYERNIEKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVA 110 Query: 132 ITDVVKPIALPTKEP-----KPGSKCLASGWGSITPT 163 +D + P+ LP +E + G K +GWG++ T Sbjct: 111 FSDYIHPVCLPDRETAASLLQAGYKGRVTGWGNLKET 147 >3F1S-B nrPDB Length = 283 Score = 143 bits (361), Expect = 7e-35, Method: Composition-based stats. Identities = 53/235 (22%), Positives = 81/235 (34%), Gaps = 34/235 (14%) Query: 37 PWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKS 95 PWQV + + + CGGV++ N+VLT A C + + + K + ++ Sbjct: 65 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV-KTYFNRTSQDPLMIKITHV 123 Query: 96 FPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK-----PGS 150 H ++ NDL LL L P P+ P K+ P + Sbjct: 124 HVHMRYDAD-----------AGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT 172 Query: 151 KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC------AGEMGG 204 + L SGW + L +TL+ E C +V VT C A Sbjct: 173 RGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD 229 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMK 259 G R+ G L G G P G + T + +++ W K M Sbjct: 230 GSVVTREHRGSWF-----LTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIMNA 277 >2WIN-I nrPDB Length = 507 Score = 142 bits (359), Expect = 1e-34, Method: Composition-based stats. Identities = 63/278 (22%), Positives = 98/278 (35%), Gaps = 62/278 (22%) Query: 34 NSQPWQVAVYY----QKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSA-Q 88 + QPWQ + + C G ++ +VLTAAHC+ + ++ + + Sbjct: 232 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSIKVSVGGEKR 287 Query: 89 HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKP 148 + HP +N++ IP D+ D+ L++L ++PI LP E Sbjct: 288 DLEIEVVLFHPNYNINGKKEAGIPEFYDY--DVALIKLKNKLKYGQTIRPICLPCTEGTT 345 Query: 149 GSKCLASGWGSITPTRWQKPDDL--QCVFITLLPNEN------------------CA--- 185 + L T + QK + L Q + + E C Sbjct: 346 RALRLP----PTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 401 Query: 186 ---------KVYLQKVTDVMLCAGEMGGGKD--TCRDDSGGPLICDG----ILQGTTSYG 230 K + VT LC G + D TCR DSGGPLI I G S+G Sbjct: 402 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 461 Query: 231 PVPCGKPGV-----P----AIYTNLIKFNSWIKDTMMK 259 V K P + NL + W+K+ + Sbjct: 462 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQD 499 >1BBR-H nrPDB Length = 150 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 44/157 (28%), Positives = 73/157 (46%), Gaps = 28/157 (17%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC VD Sbjct: 1 IVEGQDAEVGLSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTVDDLL 60 Query: 73 VWLGKNKLFQEEPSAQHR-LVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 V +GK+ + E + ++ K + HP +N + D+ LL+L +P + Sbjct: 61 VRIGKHSRTRYERKVEKISMLDKIYIHPRYNWK----------ENLDRDIALLKLKRPIE 110 Query: 132 ITDVVKPIALPTKEPK-----PGSKCLASGWGSITPT 163 ++D + P+ LP K+ G K +GWG+ T Sbjct: 111 LSDYIHPVCLPDKQTAAKLLHAGFKGRVTGWGNRRET 147 >2JET-B nrPDB Length = 128 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 44/138 (31%), Positives = 70/138 (50%), Gaps = 15/138 (10%) Query: 28 GFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWL-GKNKLFQEEP 85 G + S PWQV++ + H CGG L+ +WV+TAAHC V +V + G+ +E Sbjct: 1 GEDAIPGSWPWQVSLQDKTGFHFCGGSLISEDWVVTAAHCGVKTSDVVVAGEFDQGSDEE 60 Query: 86 SAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP--T 143 + Q +++ F +P FNM + ND+ LL+L+ PA ++ V + LP Sbjct: 61 NIQVLKIAQVFKNPKFNMFTVR-----------NDITLLKLATPAQFSETVSAVCLPNVD 109 Query: 144 KEPKPGSKCLASGWGSIT 161 + PG+ C +GWG Sbjct: 110 DDFPPGTVCATTGWGKTK 127 >3VGC-B nrPDB Length = 131 Score = 141 bits (357), Expect = 2e-34, Method: Composition-based stats. Identities = 42/141 (29%), Positives = 66/141 (46%), Gaps = 15/141 (10%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKE-HICGGVLLDRNWVLTAAHCYVDQYEVWL-GKNKLFQ 82 +V G S PWQV++ + H CGG L++ NWV+TAAHC V +V + G+ Sbjct: 1 IVNGEEAVPGSWPWQVSLQDKTGFHFCGGSLINENWVVTAAHCGVTTSDVVVAGEFDQGS 60 Query: 83 EEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALP 142 Q ++K F + +N +ND+ LL+LS A + V + LP Sbjct: 61 SSEKIQKLKIAKVFKNSKYN-----------SLTINNDITLLKLSTAASFSQTVSAVCLP 109 Query: 143 TK--EPKPGSKCLASGWGSIT 161 + + G+ C+ +GWG Sbjct: 110 SASDDFAAGTTCVTTGWGLTR 130 >1DLE-A nrPDB Length = 298 Score = 140 bits (354), Expect = 5e-34, Method: Composition-based stats. Identities = 63/278 (22%), Positives = 98/278 (35%), Gaps = 62/278 (22%) Query: 34 NSQPWQVAVYY----QKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSA-Q 88 + QPWQ + + C G ++ +VLTAAHC+ + ++ + + Sbjct: 25 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSIKVSVGGEKR 80 Query: 89 HRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKP 148 + HP +N++ IP D+ D+ L++L ++PI LP E Sbjct: 81 DLEIEVVLFHPNYNINGKKEAGIPEFYDY--DVALIKLKNKLKYGQTIRPICLPCTEGTT 138 Query: 149 GSKCLASGWGSITPTRWQKPDDL--QCVFITLLPNEN------------------CA--- 185 + L T + QK + L Q + + E C Sbjct: 139 RALRLP----PTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 194 Query: 186 ---------KVYLQKVTDVMLCAGEMGGGKD--TCRDDSGGPLICDG----ILQGTTSYG 230 K + VT LC G + D TCR DSGGPLI I G S+G Sbjct: 195 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 254 Query: 231 PVPCGKPGV-----P----AIYTNLIKFNSWIKDTMMK 259 V K P + NL + W+K+ + Sbjct: 255 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQD 292 >3H5C-B nrPDB Length = 317 Score = 140 bits (354), Expect = 5e-34, Method: Composition-based stats. Identities = 53/233 (22%), Positives = 81/233 (34%), Gaps = 34/233 (14%) Query: 37 PWQVAV-YYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKS 95 PWQV + + + CGGV++ N+VLT A C + + + K + ++ Sbjct: 106 PWQVKLTNSEGKDFCGGVIIRENFVLTTAKCSLLHRNITV-KTYFNRTSQDPLMIKITHV 164 Query: 96 FPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPK-----PGS 150 H ++ NDL LL L P P+ P K+ P + Sbjct: 165 HVHMRYDAD-----------AGENDLSLLELEWPIQCPGAGLPVCTPEKDFAEHLLIPRT 213 Query: 151 KCLASGWGSITPTRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLC------AGEMGG 204 + L SGW + L +TL+ E C +V VT C A Sbjct: 214 RGLLSGWAR---NGTDLGNSLTTRPVTLVEGEECGQVLNVTVTTRTYCERSSVAAMHWMD 270 Query: 205 GKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G R+ G L G G P G + T + +++ W K M Sbjct: 271 GSVVTREHRGSWF-----LTGVL--GSQPVGGQAHMVLVTKVSRYSLWFKQIM 316 >2OK5-A nrPDB Length = 752 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 63/278 (22%), Positives = 98/278 (35%), Gaps = 62/278 (22%) Query: 34 NSQPWQVAVYY----QKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQH 89 + QPWQ + + C G ++ +VLTAAHC+ + ++ + + Sbjct: 476 HKQPWQAKISVIRPSKGHESCMGAVVSEYFVLTAAHCFTVDDK----EHSIKVSVGGEKR 531 Query: 90 -RLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKP 148 + HP +N++ IP D+ D+ L++L ++PI LP E Sbjct: 532 DLEIEVVLFHPNYNINGKKEAGIPEFYDY--DVALIKLKNKLKYGQTIRPICLPCTEGTT 589 Query: 149 GSKCLASGWGSITPTRWQKPDDL--QCVFITLLPNEN------------------CA--- 185 + L T + QK + L Q + + E C Sbjct: 590 RALRLP----PTTTCQQQKEELLPAQDIKALFVSEEEKKLTRKEVYIKNGDKKGSCERDA 645 Query: 186 ---------KVYLQKVTDVMLCAGEMGGGKD--TCRDDSGGPLICDG----ILQGTTSYG 230 K + VT LC G + D TCR DSGGPLI I G S+G Sbjct: 646 QYAPGYDKVKDISEVVTPRFLCTGGVSPYADPNTCRGDSGGPLIVHKRSRFIQVGVISWG 705 Query: 231 PVPCGKPGV-----P----AIYTNLIKFNSWIKDTMMK 259 V K P + NL + W+K+ + Sbjct: 706 VVDVCKNQKRQKQVPAHARDFHINLFQVLPWLKEKLQD 743 >2I6S-A nrPDB Length = 517 Score = 124 bits (311), Expect = 4e-29, Method: Composition-based stats. Identities = 59/288 (20%), Positives = 106/288 (36%), Gaps = 61/288 (21%) Query: 26 VGGFNCKKNSQ---PWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQ 82 VG + + Q PW V + + + C G L+ WVLTAAHC+ D + L + + Sbjct: 230 VGNMSANASDQERTPWHVTIKPKSQETCRGALISDQWVLTAAHCFRDGNDHSLWRVNVGD 289 Query: 83 EEPS-AQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIAL 141 + + L+ K+ PGF++ Q I + +D+ LL+L++ ++ +PI L Sbjct: 290 PKSQWGKEFLIEKAVISPGFDVFAKKNQGILEF--YGDDIALLKLAQKVKMSTHARPICL 347 Query: 142 PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITL-----------------LPNENC 184 P + G + R + + L + + +C Sbjct: 348 PCTMEANLALRRPQG----STCRDHENELLNKQSVPAHFVALNGSKLNINLKMGVEWTSC 403 Query: 185 AKV-------------YLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICDG----ILQGTT 227 A+V + VTD LC+G + C+ +SGG + + G Sbjct: 404 AEVVSQEKTMFPNLTDVREVVTDQFLCSGTQED-ESPCKGESGGAVFLERRFRFFQVGLV 462 Query: 228 SYGPV-PC-------GKPGVP--------AIYTNLIKFNSWIKDTMMK 259 S+G PC + P + NL + W++ + Sbjct: 463 SWGLYNPCLGSADKNSRKRAPRSKVPPPRDFHINLFRMQPWLRQHLGD 510 >2KAI-A nrPDB Length = 80 Score = 124 bits (311), Expect = 5e-29, Method: Composition-based stats. Identities = 46/80 (57%), Positives = 59/80 (73%) Query: 25 VVGGFNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEE 84 ++GG C+KNS PWQVA+Y+ CGGVL++ WVLTAAHC D YEVWLG++ LF+ E Sbjct: 1 IIGGRECEKNSHPWQVAIYHYSSFQCGGVLVNPKWVLTAAHCKNDNYEVWLGRHNLFENE 60 Query: 85 PSAQHRLVSKSFPHPGFNMS 104 +AQ V+ FPHPGFN+S Sbjct: 61 NTAQFFGVTADFPHPGFNLS 80 >1BBR-E nrPDB Length = 109 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 29/100 (29%), Positives = 42/100 (42%), Gaps = 10/100 (10%) Query: 167 KPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD--- 220 +P LQ V + L+ C ++TD M CAG G D C DSGGP + Sbjct: 6 QPSVLQVVNLPLVERPVCKASTRIRITDNMFCAGYKPGEGKRGDACEGDSGGPFVMKSPY 65 Query: 221 ---GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G S+G C + G YT++ + WI+ + Sbjct: 66 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 104 >2HNT-F nrPDB Length = 105 Score = 118 bits (296), Expect = 2e-27, Method: Composition-based stats. Identities = 28/100 (28%), Positives = 42/100 (42%), Gaps = 10/100 (10%) Query: 167 KPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGE---MGGGKDTCRDDSGGPLICD--- 220 +P LQ V + ++ C ++TD M CAG G D C DSGGP + Sbjct: 2 QPSVLQVVNLPIVERPVCKDSTRIRITDNMFCAGYKPDEGKRGDACEGDSGGPFVMKSPF 61 Query: 221 ---GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTM 257 G S+G C + G YT++ + WI+ + Sbjct: 62 NNRWYQMGIVSWGE-GCDRDGKYGFYTHVFRLKKWIQKVI 100 >3RU4-E nrPDB Length = 96 Score = 115 bits (289), Expect = 2e-26, Method: Composition-based stats. Identities = 35/99 (35%), Positives = 48/99 (48%), Gaps = 7/99 (7%) Query: 166 QKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD----G 221 PD LQ + LL N NC K + K+ D M+CAG G +C DSGGPL+C Sbjct: 1 NTPDRLQQASLPLLSNTNCKKYWGTKIKDAMICAGAS--GVSSCMGDSGGPLVCKKNGAW 58 Query: 222 ILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 L G S+G C P +Y + +W++ T+ N Sbjct: 59 TLVGIVSWGSSTCSTS-TPGVYARVTALVNWVQQTLAAN 96 >2JET-C nrPDB Length = 99 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 32/102 (31%), Positives = 49/102 (48%), Gaps = 7/102 (6%) Query: 163 TRWQKPDDLQCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLICD-- 220 + P+ LQ + ++ +C K + K+TDVM CAG G D+C DSGGPL+C Sbjct: 1 NALKTPEKLQQAALPIVSEADCKKSWGSKITDVMTCAGAS--GVDSCMGDSGGPLVCQKD 58 Query: 221 --GILQGTTSYGPVPCGKPGVPAIYTNLIKFNSWIKDTMMKN 260 L G S+G C P +Y+ + W++ + N Sbjct: 59 GVWTLAGIVSWGSGVCSTS-TPGVYSRVTALMPWVQQILEAN 99 >1EPT-B nrPDB Length = 82 Score = 104 bits (260), Expect = 4e-23, Method: Composition-based stats. Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 11/93 (11%) Query: 69 DQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSK 128 + +V LG++ + E + Q +K HP FN G ND+ML++LS Sbjct: 1 SRIQVRLGEHNIDVLEGNEQFINAAKIITHPNFN-----------GNTLDNDIMLIKLSS 49 Query: 129 PADITDVVKPIALPTKEPKPGSKCLASGWGSIT 161 PA + V ++LP G++CL SGWG+ Sbjct: 50 PATLNSRVATVSLPRSCAAAGTECLISGWGNTK 82 >2HNT-C nrPDB Length = 70 Score = 75.3 bits (184), Expect = 2e-14, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 34/70 (48%), Gaps = 12/70 (17%) Query: 25 VVGGFNCKKNSQPWQVAVYYQ--KEHICGGVLLDRNWVLTAAHCY----------VDQYE 72 +V G + + PWQV ++ + +E +CG L+ WVLTAAHC + Sbjct: 1 IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPWDKNFTENDLL 60 Query: 73 VWLGKNKLFQ 82 V +GK+ + Sbjct: 61 VRIGKHSRTR 70 >2HNT-E nrPDB Length = 81 Score = 74.2 bits (181), Expect = 6e-14, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 37/82 (45%), Gaps = 15/82 (18%) Query: 87 AQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEP 146 + ++ K + HP +N + D+ L++L KP +D + P+ LP +E Sbjct: 3 EKISMLEKIYIHPRYNWR----------ENLDRDIALMKLKKPVAFSDYIHPVCLPDRET 52 Query: 147 -----KPGSKCLASGWGSITPT 163 + G K +GWG++ T Sbjct: 53 AASLLQAGYKGRVTGWGNLKET 74 >1P3E-A nrPDB Length = 215 Score = 36.4 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 36/126 (28%), Gaps = 23/126 (18%) Query: 40 VAVYYQKEHICGGVLLDRNWVLTAAHCYVD--------QYEVWLGKNKLFQEEPSAQHRL 91 +A C G L+ N +LT HC + + V+ G N SA Sbjct: 22 IAYITFGGSSCTGTLIAPNKILTNGHCVYNTASRSYSAKGSVYPGMNDSTAVNGSANM-- 79 Query: 92 VSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSK 151 + D +++ +I + V ++ G+ Sbjct: 80 -----------TEFYVPSGYINTGASQYDFAVIKTDT--NIGNTVGYRSIRQVTNLTGTT 126 Query: 152 CLASGW 157 SG+ Sbjct: 127 IKISGY 132 >2EA3-A nrPDB Length = 189 Score = 34.9 bits (79), Expect = 0.035, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 13/29 (44%) Query: 211 DDSGGPLICDGILQGTTSYGPVPCGKPGV 239 DSGG L+ QG TS G C G Sbjct: 135 GDSGGSLLAGNQAQGVTSGGSGNCRTGGT 163 >2PFE-A nrPDB Length = 186 Score = 34.9 bits (79), Expect = 0.041, Method: Composition-based stats. Identities = 15/47 (31%), Positives = 17/47 (36%), Gaps = 9/47 (19%) Query: 192 VTDVMLCAGEMGGGKDTCRDDSGGPLICDGILQGTTSYGPVPCGKPG 238 +T CA DSGGP + QG TS G C G Sbjct: 128 LTRTTACAEG---------GDSGGPWLTGSQAQGVTSGGTGDCRSGG 165 >2OUA-A nrPDB Length = 188 Score = 32.9 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 12/29 (41%) Query: 211 DDSGGPLICDGILQGTTSYGPVPCGKPGV 239 DSGG I QG TS G C G Sbjct: 141 GDSGGSFISGTQAQGVTSGGSGNCRTGGT 169 >5ILB-A nrPDB Length = 474 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 16/47 (34%), Gaps = 2/47 (4%) Query: 29 FNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWL 75 S PWQ Q ++ +LT AHC +V + Sbjct: 17 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKV 61 >4FLN-A nrPDB Length = 539 Score = 32.9 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 16/47 (34%), Gaps = 2/47 (4%) Query: 29 FNCKKNSQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWL 75 S PWQ Q ++ +LT AHC +V + Sbjct: 57 HTAPDYSLPWQ--KQRQFTSTGSAFMIGDGKLLTNAHCVEHDTQVKV 101 >2SFA-A nrPDB Length = 191 Score = 32.5 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 11/29 (37%) Query: 211 DDSGGPLICDGILQGTTSYGPVPCGKPGV 239 DSGG L G TS G C G Sbjct: 145 GDSGGALFAGSTALGLTSGGSGNCRTGGT 173 >5JYK-A nrPDB Length = 566 Score = 31.8 bits (71), Expect = 0.33, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 16/41 (39%), Gaps = 2/41 (4%) Query: 35 SQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWL 75 S PWQ Y G ++ VLT AH +V L Sbjct: 115 SLPWQRKRQYSSGSS--GFIIGGRRVLTNAHSVEHHTQVKL 153 >5ILA-A nrPDB Length = 301 Score = 31.4 bits (70), Expect = 0.46, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 16/41 (39%), Gaps = 2/41 (4%) Query: 35 SQPWQVAVYYQKEHICGGVLLDRNWVLTAAHCYVDQYEVWL 75 S PWQ Y G ++ VLT AH +V L Sbjct: 115 SLPWQRKRQYSSGSS--GFIIGGRRVLTNAHSVEHHTQVKL 153 >3LT3-A nrPDB Length = 217 Score = 31.0 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 31/177 (17%), Positives = 53/177 (29%), Gaps = 41/177 (23%) Query: 52 GVLLDRNWVLTAAHCYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTI 111 G ++ + V+T AH V G N + + Sbjct: 42 GFVISPDRVMTNAH-------VVAGSNNVTVYAGDK-------------------PFEAT 75 Query: 112 PPGADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDL 171 D S D+ +L A P+ + K G+ + G+ P + Sbjct: 76 VVSYDPSVDVAIL-----AVPHLPPPPLVFAAEPAKTGADVVVLGY-PGGGNFTATPARI 129 Query: 172 QCVFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCRDDSGGPLI-CDGILQGTT 227 + I L + + VT + D + D+GGPLI +G + G Sbjct: 130 REA-IRLSGPDIYGD--PEPVTRDVY-----TIRADVEQGDAGGPLIDLNGQVLGVV 178 >2SGA-A nrPDB Length = 181 Score = 31.0 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 11/29 (37%) Query: 211 DDSGGPLICDGILQGTTSYGPVPCGKPGV 239 DSGG L G TS G C G Sbjct: 135 GDSGGSLFAGSTALGLTSGGSGNCRTGGT 163 >5MM8-A nrPDB Length = 204 Score = 30.6 bits (68), Expect = 0.61, Method: Composition-based stats. Identities = 31/201 (15%), Positives = 55/201 (27%), Gaps = 41/201 (20%) Query: 74 WLGKNKLFQEEPSAQHRLV-SKSFPHPG--FNMSLLMLQTIPPGADFSNDLMLLRLSKPA 130 +GKN + + + + HP +N D+ +L + A Sbjct: 30 IVGKNTIVTNKHVVAGMEIGAHIIAHPNGEYNNGGFYKVKKIVRYSGQEDIAILHVEDKA 89 Query: 131 ------DITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENC 184 + D + + + E K + G+ ++Q E+ Sbjct: 90 VHPKNRNFKDYTGILKIAS-EAKENERISIVGYPEPYINKFQM-------------YEST 135 Query: 185 AKVYLQKVTDVMLCAGEMGGGKDTCR--DDSGGP-LICDGILQGTTSYGPVPCGKPGV-P 240 KV V M+ D +SG + G G P K Sbjct: 136 GKVL--SVKGNMIIT-------DAFVEPGNSGSAVFNSKYEVVGVHFGGNGPGNKSTKGY 186 Query: 241 AIYTNLIKFNSWIKDTMMKNA 261 +Y F+ IK + N Sbjct: 187 GVY-----FSPEIKKFIADNT 202 >5MRT-A nrPDB Length = 205 Score = 30.2 bits (67), Expect = 1.0, Method: Composition-based stats. Identities = 14/30 (46%), Positives = 17/30 (56%), Gaps = 1/30 (3%) Query: 208 TCRDDSGG-PLICDGILQGTTSYGPVPCGK 236 T R DSGG + G QG TS G +P G+ Sbjct: 144 TGRGDSGGSWITAAGQAQGLTSGGNLPAGQ 173 >3QO6-A nrPDB Length = 348 Score = 29.1 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 32/164 (19%), Positives = 49/164 (29%), Gaps = 39/164 (23%) Query: 67 YVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRL 126 V Y V G + L G D D+ +LR+ Sbjct: 66 IVTNYHVIRGASDLRVTLADQTTFDAKVV------------------GFDQDKDVAVLRI 107 Query: 127 SKPADITDVVKPIAL-PTKEPKPGSKCLASGWGSITPTRWQKPDDLQCVFITLLPNENCA 185 P + ++PI + + + G K A G + L I+ L E + Sbjct: 108 DAP---KNKLRPIPVGVSADLLVGQKVFAIG------NPFGLDHTLTTGVISGLRREISS 158 Query: 186 KVYLQKVTDVMLCAGEMGGGKDTC--RDDSGGPLI-CDGILQGT 226 + + DV D +SGGPL+ G L G Sbjct: 159 AATGRPIQDV--------IQTDAAINPGNSGGPLLDSSGTLIGI 194 >4NSY-A nrPDB Length = 275 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 36/99 (36%), Gaps = 7/99 (7%) Query: 40 VAVYYQKEHICGGVLLDRN------WVLTAAHCYVDQYEVWLGK-NKLFQEEPSAQHRLV 92 A Q C G L++ + + LTA HC + + + + + Sbjct: 26 AAYSKQGTMWCTGSLVNNSANDKKMYFLTANHCGMTTAAIASSMVVYWNYQNSTCRAPGS 85 Query: 93 SKSFPHPGFNMSLLMLQTIPPGADFSNDLMLLRLSKPAD 131 S S + +++ + + ++D LL L+ A+ Sbjct: 86 SSSGANGDGSLAQSQTGAVVRATNAASDFTLLELNTAAN 124 >4FVB-A nrPDB Length = 152 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 10/23 (43%) Query: 211 DDSGGPLICDGILQGTTSYGPVP 233 D+GG L C + G S G Sbjct: 110 GDAGGILRCQHGVVGIVSTGGNG 132 >3W95-A nrPDB Length = 171 Score = 29.1 bits (64), Expect = 1.9, Method: Composition-based stats. Identities = 8/23 (34%), Positives = 10/23 (43%) Query: 211 DDSGGPLICDGILQGTTSYGPVP 233 D+GG L C + G S G Sbjct: 129 GDAGGILRCQHGVVGIVSTGGNG 151 >1HPG-A nrPDB Length = 187 Score = 28.7 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 26/183 (14%), Positives = 48/183 (26%), Gaps = 47/183 (25%) Query: 56 DRNWVLTAAHC--YVDQYEVWLGKNKLFQEEPSAQHRLVSKSFPHPGFNMSLLMLQTIPP 113 + +TA HC + G + + E ++ + + + T+ Sbjct: 24 GARYFVTAGHCTNISANWSASSGGSVVGVREGTS---FPTNDYGIVRYTDGSSPAGTVDL 80 Query: 114 GADFSNDLMLLRLSKPADITDVVKPIALPTKEPKPGSKCLASGWGSITPTRWQKPDDLQC 173 + D+ + A + +K K GS + + Sbjct: 81 YNGSTQDISS---AANAVVGQAIK---------KSGSTTKVT------------SGTVTA 116 Query: 174 VFITLLPNENCAKVYLQKVTDVMLCAGEMGGGKDTCR--DDSGGPLICDGILQGTTSYGP 231 V +T+ Y M+ C DSGG + G S G Sbjct: 117 VNVTV--------NYGDGPVYNMV-------RTTACSAGGDSGGAHFAGSVALGIHS-GS 160 Query: 232 VPC 234 C Sbjct: 161 SGC 163 >2M5T-A nrPDB Length = 142 Score = 28.3 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%), Gaps = 7/50 (14%) Query: 185 AKVYLQKVTDVMLCAGEMGGGKDTCR-DDSGGPLICDGILQGTTSYGPVP 233 + Y + + +L G+ C D+GG L+C + G + G Sbjct: 82 TQYYPKHIQYNLL------IGEGPCVPGDAGGKLLCRHGVIGIITAGGDG 125 >1DUE-A nrPDB Length = 242 Score = 28.3 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 47/124 (37%), Gaps = 19/124 (15%) Query: 42 VYYQKEHICGGVLLDRNWVLTAAH----CYVDQYEVWLGKNKLFQEEPSAQHRLVSKSFP 97 V+ + + GVL+ +N VLT H D +V + + + + P Sbjct: 49 VFVKGQTSATGVLIGKNTVLTNRHIAKFANGDPSKVSFRPSINTDDNGNTET-------P 101 Query: 98 HPGFNMSLLMLQTIPPGADFSNDLMLLRLSKP---ADITDVVKPIAL-PTKEPKPGSKCL 153 + + + ++ + G DL L+RL + D + P + + + K G K Sbjct: 102 YGEYEVKEILQEPFGAGV----DLALIRLKPDQNGVSLGDKISPAKIGTSNDLKDGDKLE 157 Query: 154 ASGW 157 G+ Sbjct: 158 LIGY 161 >2HRV-A nrPDB Length = 142 Score = 28.3 bits (62), Expect = 3.7, Method: Composition-based stats. Identities = 11/47 (23%), Positives = 20/47 (42%), Gaps = 7/47 (14%) Query: 185 AKVYLQKVTDVMLCAGEMGGGKDTCR-DDSGGPLICDGILQGTTSYG 230 ++ Y + + +L G+ C D GG L+C + G + G Sbjct: 83 SEYYPKHIQYNLL------IGEGPCEPGDCGGKLLCKHGVIGIVTAG 123 >1PNF-A nrPDB Length = 314 Score = 28.3 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 10/26 (38%), Positives = 11/26 (42%) Query: 139 IALPTKEPKPGSKCLASGWGSITPTR 164 I LPT K + SGWG P Sbjct: 173 IQLPTNTEKAYLRTTISGWGHAKPYD 198 >5MRR-A nrPDB Length = 199 Score = 27.9 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 21/57 (36%), Gaps = 10/57 (17%) Query: 205 GKDTC--RDDSGG-PLICDGILQGTTSYGPVP-----CGKP--GVPAIYTNLIKFNS 251 + C R DSGG G QG S G V CG P +++ + S Sbjct: 134 QGNACMGRGDSGGSWFTSAGQAQGVMSGGNVQSNGNNCGIPASQRSSLFERVGPILS 190 >4B6E-A nrPDB Length = 683 Score = 27.5 bits (60), Expect = 6.4, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 13/29 (44%), Gaps = 3/29 (10%) Query: 210 RDDSGGPLIC-DGILQGTTSYGPVPCGKP 237 + SGGPL+C G G + C + Sbjct: 171 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 197 >4NWK-A nrPDB Length = 219 Score = 27.2 bits (59), Expect = 7.0, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 13/29 (44%), Gaps = 3/29 (10%) Query: 210 RDDSGGPLICD-GILQGTTSYGPVPCGKP 237 + SGGPL+C G G + C + Sbjct: 151 KGSSGGPLLCPAGHAVGI--FRAAVCTRG 177 >6FE6-A nrPDB Length = 165 Score = 27.2 bits (59), Expect = 8.0, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 13/29 (44%), Gaps = 3/29 (10%) Query: 210 RDDSGGPLIC-DGILQGTTSYGPVPCGKP 237 + SGGPL+C G G + C + Sbjct: 115 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 141 >6C2N-A nrPDB Length = 203 Score = 27.2 bits (59), Expect = 8.3, Method: Composition-based stats. Identities = 8/18 (44%), Positives = 10/18 (55%), Gaps = 1/18 (5%) Query: 210 RDDSGGPLICD-GILQGT 226 + SGGPL+C G G Sbjct: 157 KGSSGGPLLCPAGHAVGI 174 >4IC5-A nrPDB Length = 291 Score = 27.2 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 20/44 (45%), Gaps = 4/44 (9%) Query: 114 GADFSNDLMLLRLSKPADITDVVKPIAL-PTKEPKPGSKCLASG 156 G D NDL +L++ + P+ L + + + G C A G Sbjct: 133 GLDPDNDLAVLKIETE---GRELNPVVLGTSNDLRVGQSCFAIG 173 >4U01-A nrPDB Length = 203 Score = 26.8 bits (58), Expect = 8.8, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 13/29 (44%), Gaps = 3/29 (10%) Query: 210 RDDSGGPLIC-DGILQGTTSYGPVPCGKP 237 + SGGPL+C G G + C + Sbjct: 137 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 163 >4K8B-A nrPDB Length = 181 Score = 26.8 bits (58), Expect = 9.0, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 13/29 (44%), Gaps = 3/29 (10%) Query: 210 RDDSGGPLIC-DGILQGTTSYGPVPCGKP 237 + SGGPL+C G G + C + Sbjct: 136 KGSSGGPLLCPSGHAVGI--FRAAVCTRG 162 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.152 0.547 Lambda K H 0.267 0.0466 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,438,378 Number of Sequences: 36641 Number of extensions: 563721 Number of successful extensions: 2638 Number of sequences better than 10.0: 196 Number of HSP's better than 10.0 without gapping: 325 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 1022 Number of HSP's gapped (non-prelim): 381 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (26.8 bits)