BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P35731 (278 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4HBG-A nrPDB 581 e-167 2PNF-A nrPDB 88 4e-18 2HQ1-A nrPDB 88 4e-18 3LYL-A nrPDB 87 5e-18 3FTP-A nrPDB 82 2e-16 4BO1-A nrPDB 79 3e-15 3RSH-A nrPDB 77 7e-15 3GRP-A nrPDB 77 8e-15 2PH3-A nrPDB 76 2e-14 2CDH-G nrPDB 74 5e-14 4CQM-B nrPDB 74 5e-14 4JRO-A nrPDB 74 6e-14 5CDY-A nrPDB 74 6e-14 2C07-A nrPDB 74 6e-14 4KMS-A nrPDB 74 6e-14 3EZL-A nrPDB 73 1e-13 3VZS-A nrPDB 71 6e-13 1Q7C-A nrPDB 70 1e-12 4RZH-A nrPDB 70 1e-12 3WOH-A nrPDB 70 1e-12 3EMK-A nrPDB 69 3e-12 3F9I-A nrPDB 68 3e-12 4M8S-A nrPDB 67 6e-12 2UVD-A nrPDB 67 9e-12 4DMM-A nrPDB 64 8e-11 5VT6-A nrPDB 63 1e-10 4CQL-A nrPDB 62 3e-10 3V2G-A nrPDB 60 1e-09 3OSU-A nrPDB 60 1e-09 4IS3-A nrPDB 60 1e-09 1SNY-A nrPDB 59 2e-09 2GDZ-A nrPDB 59 3e-09 2NWQ-A nrPDB 58 4e-09 4MOW-A nrPDB 58 4e-09 4IIN-A nrPDB 58 4e-09 4NBT-A nrPDB 58 5e-09 2O23-A nrPDB 57 7e-09 1AE1-A nrPDB 55 3e-08 4HP8-A nrPDB 55 4e-08 4Z9Y-A nrPDB 54 5e-08 5B1Y-A nrPDB 54 5e-08 2CFC-A nrPDB 54 6e-08 2AE2-A nrPDB 54 6e-08 4NBV-A nrPDB 54 6e-08 2NM0-A nrPDB 54 1e-07 5OJG-A nrPDB 54 1e-07 1E3W-A nrPDB 53 1e-07 2ZAT-A nrPDB 53 1e-07 3WTC-A nrPDB 52 2e-07 3O4R-A nrPDB 52 3e-07 5IZ4-A nrPDB 50 8e-07 4K6F-A nrPDB 50 9e-07 3RKU-A nrPDB 50 9e-07 3OEC-A nrPDB 48 5e-06 3U5T-A nrPDB 48 5e-06 1K2W-A nrPDB 47 6e-06 1GEE-A nrPDB 47 7e-06 4DBZ-A nrPDB 47 7e-06 3D3W-A nrPDB 47 8e-06 6CI9-A nrPDB 47 1e-05 2X9N-A nrPDB 47 1e-05 1NFF-A nrPDB 46 1e-05 1CYD-A nrPDB 45 3e-05 2B4Q-A nrPDB 45 3e-05 4DA9-A nrPDB 44 5e-05 5JS6-A nrPDB 44 7e-05 1UZM-A nrPDB 44 7e-05 6NRP-A nrPDB 44 7e-05 1X1T-A nrPDB 43 2e-04 1B15-A nrPDB 42 3e-04 2BFA-A nrPDB 41 5e-04 2QHX-A nrPDB 41 5e-04 3A28-C nrPDB 41 5e-04 1GEG-A nrPDB 41 5e-04 4IIV-A nrPDB 41 5e-04 1P33-A nrPDB 41 6e-04 2AG5-A nrPDB 41 7e-04 1YXM-A nrPDB 40 9e-04 3KZV-A nrPDB 40 0.001 1MG5-A nrPDB 40 0.001 5YSS-A nrPDB 40 0.001 2Q2Q-A nrPDB 40 0.002 4RZI-B nrPDB 39 0.002 4FC7-A nrPDB 39 0.002 3WYE-A nrPDB 39 0.002 3AUT-A nrPDB 39 0.002 1OAA-A nrPDB 39 0.003 4E6P-A nrPDB 39 0.003 3E9N-A nrPDB 39 0.003 5ILO-A nrPDB 38 0.004 2FWM-X nrPDB 38 0.004 5TF4-A nrPDB 38 0.004 1DOH-A nrPDB 38 0.005 3RWB-A nrPDB 38 0.006 5ITV-A nrPDB 38 0.006 4Z3K-A nrPDB 37 0.007 4HWK-A nrPDB 37 0.007 3W8F-A nrPDB 37 0.007 3UF0-A nrPDB 37 0.008 5L51-A nrPDB 37 0.010 3DWF-A nrPDB 37 0.012 3V8B-A nrPDB 37 0.013 2HSD-A nrPDB 37 0.013 2HRB-A nrPDB 37 0.014 5PGZ-A nrPDB 36 0.017 3T7C-A nrPDB 36 0.018 4AVY-A nrPDB 36 0.022 1H5Q-A nrPDB 36 0.023 4TRR-A nrPDB 35 0.036 3GRK-A nrPDB 35 0.036 3OIG-A nrPDB 35 0.037 3V2H-A nrPDB 35 0.038 5T5Q-A nrPDB 35 0.038 5LCX-A nrPDB 34 0.078 3PXX-A nrPDB 34 0.083 1O5I-A nrPDB 34 0.084 5OVL-A nrPDB 33 0.095 5OVJ-A nrPDB 33 0.11 4EGF-A nrPDB 33 0.12 3OML-A nrPDB 33 0.16 3BHI-A nrPDB 33 0.16 3UVE-A nrPDB 32 0.22 6CGE-A nrPDB 32 0.25 1A27-A nrPDB 32 0.25 1N5D-A nrPDB 32 0.28 3U4C-A nrPDB 32 0.33 5KOI-A nrPDB 32 0.38 3O26-A nrPDB 31 0.60 3OIC-A nrPDB 30 0.78 2EW8-A nrPDB 30 1.3 3PF7-A nrPDB 30 1.5 3PPI-A nrPDB 29 1.9 3ZV3-A nrPDB 29 2.3 1G4W-R nrPDB 29 2.3 3R3S-A nrPDB 28 3.4 3GLF-B nrPDB 28 4.2 4CR6-A nrPDB 28 4.6 1BDB-A nrPDB 28 5.1 4NK4-A nrPDB 28 5.1 1AHH-A nrPDB 27 7.7 1NJG-A nrPDB 27 9.7 >4HBG-A nrPDB Length = 286 Score = 581 bits (1498), Expect = e-167, Method: Compositional matrix adjust. Identities = 278/278 (100%), Positives = 278/278 (100%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ Sbjct: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC Sbjct: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN Sbjct: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL Sbjct: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET Sbjct: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 >2PNF-A nrPDB Length = 248 Score = 88.2 bits (217), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 73/270 (27%), Positives = 125/270 (46%), Gaps = 45/270 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V++VTG+TRGIG+AI +KL G + II G++ E + A + IA Sbjct: 9 VSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEE---------------IAN 53 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + H ++ + + + +++ + +++L+N AG+T+ Sbjct: 54 KYGVKAHGVEMN-------LLSEESINKAFEEIYNLVDG---------IDILVNNAGITR 97 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L +R + ++++ VN +T ++ M+K +RW IVNISS++ Sbjct: 98 DKLFLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIK--QRWGR---------IVNISSVV 146 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G G YS +KA L FT+ LA E+ PRN+ ++PG ++ TDM L E K Sbjct: 147 --GFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAPGFIE-TDMTAVLSEEIK 203 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + I +P E+A V L S A Sbjct: 204 QKYKEQIPLGRFGSPEEVANVVLFLCSELA 233 >2HQ1-A nrPDB Length = 247 Score = 87.8 bits (216), Expect = 4e-18, Method: Compositional matrix adjust. Identities = 79/266 (29%), Positives = 124/266 (46%), Gaps = 45/266 (16%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 AIVTG++RG+GKAI KL G + ++ GS T++D A A + Sbjct: 8 AIVTGSSRGLGKAIAWKLGNMGANIVLNGSP----ASTSLD--------------ATAEE 49 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 FK + D K+ ++ T D + +++L+N AG+T++ Sbjct: 50 FKAAGINVVVAKGD----VKNPEDVENMVKTAMDAFGR---------IDILVNNAGITRD 96 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 +L ++ + D++N N S T K M+K + SG+ I+NI+SI Sbjct: 97 TLMLKMSEKDWDDVLNTNLKSAYLCTKAVSKIMLKQK------SGK-----IINITSI-- 143 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 +G + G + Y+ASKA L FT+ +A E + I C ++PG++K TDM LP + KE Sbjct: 144 AGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYCNAVAPGIIK-TDMTDVLPDKVKE 202 Query: 247 MLERTIGASGTSAPAEIAEEVWSLYS 272 M I P E+A V L S Sbjct: 203 MYLNNIPLKRFGTPEEVANVVGFLAS 228 >3LYL-A nrPDB Length = 247 Score = 87.4 bits (215), Expect = 5e-18, Method: Compositional matrix adjust. Identities = 72/270 (26%), Positives = 122/270 (45%), Gaps = 46/270 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA+RGIG + L KG + + +++ S E+ + + G Sbjct: 7 VALVTGASRGIGFEVAHALASKGATVVGTATSQASAEK--FENSMKEKG----------- 53 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 FK L+ + I+ F ++ + +++L+N AG+T+ Sbjct: 54 -FKARGLVLNISDIESIQNF---------FAEI---------KAENLAIDILVNNAGITR 94 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++L +R + + Q ++N N S M+ C++ MMK +RW I++I S++ Sbjct: 95 DNLMMRMSEDEWQSVINTNLSSIFRMSKECVRGMMK--KRWGR---------IISIGSVV 143 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G PG + Y A+KA + F++ LA E+ RNI ++PG + TDM L E K Sbjct: 144 --GSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNVVAPGFI-ATDMTDKLTDEQK 200 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I + P +IA V L S A Sbjct: 201 SFIATKIPSGQIGEPKDIAAAVAFLASEEA 230 >3FTP-A nrPDB Length = 270 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 74/267 (27%), Positives = 121/267 (45%), Gaps = 46/267 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VAIVTGA+RGIG+AI +L ++G I +T+ E I Sbjct: 30 VAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAE-------------------GIGA 70 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 FK+ E + D +T D + + E +N+L+N AG+TQ Sbjct: 71 AFKQA----GLEGRGAVLNVND--------ATAVDALVESTLKEF-GALNVLVNNAGITQ 117 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L++R + +++ N + ++ ++ MMK++ G+ IVNI+S++ Sbjct: 118 DQLAMRMKDDEWDAVIDTNLKAVFRLSRAVLRPMMKAR------GGR-----IVNITSVV 166 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G PG Y+A+KA ++ T LA E+ R I ++PG + TDM + LP E + Sbjct: 167 --GSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNCVAPGFID-TDMTKGLPQEQQ 223 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYS 272 L+ I +P +IA V L S Sbjct: 224 TALKTQIPLGRLGSPEDIAHAVAFLAS 250 >4BO1-A nrPDB Length = 269 Score = 78.6 bits (192), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 79/275 (28%), Positives = 119/275 (43%), Gaps = 56/275 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILG-----STKESIERTAIDRGQLQSGLSYQRQ 60 VA+VTGA+RGIG+AI +L + L +++G S E I T G +GL Sbjct: 29 VALVTGASRGIGQAIALELGR--LGAVVIGTATSASGAEKIAETLKANGVEGAGL----- 81 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 LD S + + L+ L P +++N Sbjct: 82 ------------VLDVSSDESVA-----ATLEHIQQHLGQPL-------------IVVNN 111 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T+++L VR + D++N N S ++ ++ M K+ RW I+N Sbjct: 112 AGITRDNLLVRMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKA--RWGR---------IIN 160 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 I S++ G M G + Y+A+KA L FT LA E+ R I ++PG + TDM + L Sbjct: 161 IGSVV--GAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFID-TDMTREL 217 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 P +E L I EIA+ V L S A Sbjct: 218 PEAQREALLGQIPLGRLGQAEEIAKVVGFLASDGA 252 >3RSH-A nrPDB Length = 251 Score = 77.0 bits (188), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 71/267 (26%), Positives = 118/267 (44%), Gaps = 49/267 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA+RGIGKAI + L ++G I G + A AI Sbjct: 14 VALVTGASRGIGKAIAELLAERGAKVI---------------------GTATSESGAQAI 52 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 DY +G + + + L +++ V++L+N AG+T+ Sbjct: 53 S--------DYLGDNGKGMALNVTNPESIEAVLKAITDEFGG------VDILVNNAGITR 98 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++L +R + DIM N S ++ ++ MMK + + I+N+ S++ Sbjct: 99 DNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKKR-----------QGRIINVGSVV 147 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G M G + Y+A+KA + FT+ +A E+ R + T++PG ++ TDM + L E + Sbjct: 148 --GTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIE-TDMTKALNDEQR 204 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYS 272 + A P EIA V L S Sbjct: 205 TATLAQVPAGRLGDPREIASAVAFLAS 231 >3GRP-A nrPDB Length = 266 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 70/243 (28%), Positives = 110/243 (45%), Gaps = 51/243 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGAT GIG+AI + +G + G+ ++ ++ A D G+ D Sbjct: 30 ALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGK---------------D 74 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYY-VNLLINCAGLTQ 125 + L DR +KQ ER +++L+N AG+T+ Sbjct: 75 VFVFSANL-----------SDRKSIKQLAEVA----------EREMEGIDILVNNAGITR 113 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L VR D++ VN + T+T I MM+ RR+ I+NI+SI+ Sbjct: 114 DGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSMMR--RRYGR---------IINITSIV 162 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G + PG + Y A+KA L F++ LA E+ RNI I+PG +K + M L + K Sbjct: 163 --GVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIAPGFIK-SAMTDKLNEKQK 219 Query: 246 EML 248 E + Sbjct: 220 EAI 222 >2PH3-A nrPDB Length = 245 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 54/162 (33%), Positives = 82/162 (50%), Gaps = 14/162 (8%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 ++ L+N AG+T+++L VR + ++ N + T +K MMK+ R+ Sbjct: 81 LDTLVNNAGITRDTLLVRMKDEDWEAVLEANLSAVFRTTREAVKLMMKA--RFGR----- 133 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 IVNI+S++ G + PG + Y ASKA L FT +A E R I ++PG ++ Sbjct: 134 ----IVNITSVV--GILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVAPGFIE- 186 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 T+M + LP E KE + I A P E+AE V L S A Sbjct: 187 TEMTERLPQEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSEKA 228 >2CDH-G nrPDB Length = 244 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 67/262 (25%), Positives = 115/262 (43%), Gaps = 49/262 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 PV +VTGA+RGIGKAI L + G C +L ++Y R A Sbjct: 2 PVVVVTGASRGIGKAIALSLGKAG--CKVL--------------------VNYARSAKAA 39 Query: 65 IDFKKWPHWLDYESYDG--IEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 + K E+Y G I + D + + + W +++++N AG Sbjct: 40 EEVSK-----QIEAYGGQAITFGGDVSKEADVEAMMKTAIDAWGT------IDVVVNNAG 88 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 +T+++L +R SQ +++++N T K MMK + + I+NI+ Sbjct: 89 ITRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKIMMKKR-----------KGRIINIA 137 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S++ G + G + Y+A+KA + F++ A E RNI + PG + +DM L Sbjct: 138 SVV--GLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIA-SDMTAKLGE 194 Query: 243 EAKEMLERTIGASGTSAPAEIA 264 + ++ + TI T P +A Sbjct: 195 DMEKKILGTIPLGRTGQPENVA 216 >4CQM-B nrPDB Length = 244 Score = 74.3 bits (181), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 68/265 (25%), Positives = 108/265 (40%), Gaps = 52/265 (19%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V V G +RGIG+A+ Q + +KG ++ E + A D G S C +A Sbjct: 11 VCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS----CDVAK 66 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + + + E + G VN L+N AG+ + Sbjct: 67 EHDVQNTFEELEKHLG-------------------------------RVNFLVNAAGINR 95 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L VRT + ++ N + + ++ M++ Q +IVN+ SI+ Sbjct: 96 DGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQG-----------GSIVNVGSIV 144 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G G SVYSASK L F+ LA E+ + IR ++PG V TDM ++L + Sbjct: 145 --GLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH-TDMTKDLK---E 198 Query: 246 EMLERTIGASGTSAPAEIAEEVWSL 270 E L++ I E+A V L Sbjct: 199 EHLKKNIPLGRFGETIEVAHAVVFL 223 >4JRO-A nrPDB Length = 271 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 75/270 (27%), Positives = 120/270 (44%), Gaps = 51/270 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTG +RGIG+ I L ++G + + E+ E TA + A Sbjct: 31 VAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETA-------------KLVA-- 75 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 H ++ +E K + + F ER V++L+N AG+T Sbjct: 76 ------EHGVE------VEAMKANVAIAEDVDAFFKQAI-----ERFGRVDILVNNAGIT 118 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + D++N+N T + MMK QR I+N++S+ Sbjct: 119 RDNLLMRMKEDEWDDVININLKGTFLCTKAVSRTMMK-QRAGK----------IINMASV 167 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G + G + Y ASKA + T+ A E+ PR I ++PG + TDM L + Sbjct: 168 V--GLIGNAGQANYVASKAGVIGLTKTTARELAPRGINVNAVAPGFIT-TDMTDKLDEKT 224 Query: 245 KE-MLERT-IGASGTSAPAEIAEEVWSLYS 272 KE ML + +GA GT+ +IA V L S Sbjct: 225 KEAMLAQIPLGAYGTT--EDIANAVLFLAS 252 >5CDY-A nrPDB Length = 244 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 71/271 (26%), Positives = 126/271 (46%), Gaps = 51/271 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKE-SIERTAIDRGQLQSGLSYQRQCAIA 64 +A+VTGA+RGIG+AI + L ++G +C+I +T E E + G+ GL Sbjct: 7 IALVTGASRGIGRAIAELLVERG-ACVIGTATSEKGAEAISAYLGENGKGL--------- 56 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + +D S D + ++ ++ V++L+N AG+T Sbjct: 57 -----MLNVVDPTSIDTV-----LATIRAEFGE----------------VDILVNNAGIT 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + QDI++ N S ++ ++ MMK +R+ I+ I S+ Sbjct: 91 RDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVMRAMMK--KRFGR---------IITIGSV 139 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G M G Y+A+KA + F++ LA E+ R I ++PG ++ TDM + L + Sbjct: 140 V--GTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVAPGFIE-TDMTRTLTDDQ 196 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + A+ EIA V L S A Sbjct: 197 RAGILAQVPANRLGDAKEIASAVAFLASDEA 227 >2C07-A nrPDB Length = 285 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 77/259 (29%), Positives = 119/259 (45%), Gaps = 46/259 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA RGIG+ I K+ K +S +I I RT Q+ C + Sbjct: 46 VALVTGAGRGIGREIA-KMLAKSVSHVIC------ISRT-------------QKSCDSVV 85 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D K YES Y D K++ S + + N V++L+N AG+T+ Sbjct: 86 DEIKS---FGYESSG---YAGDVSK-KEEISEVINKILTEHKN-----VDILVNNAGITR 133 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++L +R + +D++ N S +T K M+ + R+ I+NISSI+ Sbjct: 134 DNLFLRMKNDEWEDVLRTNLNSLFYITQPISKRMINN--RYGR---------IINISSIV 182 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G G + YS+SKA + FT+ LA E+ RNI I+PG + +DM + + K Sbjct: 183 --GLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPGFIS-SDMTDKISEQIK 239 Query: 246 EMLERTIGASGTSAPAEIA 264 + + I A P E+A Sbjct: 240 KNIISNIPAGRMGTPEEVA 258 >4KMS-A nrPDB Length = 249 Score = 73.9 bits (180), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 74/276 (26%), Positives = 119/276 (43%), Gaps = 61/276 (22%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +AIVTG TRGIGKA +L KGL+ + Sbjct: 12 IAIVTGGTRGIGKATALELKNKGLTVVA-------------------------------- 39 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTL--FDPCN---KWSNNERRYYVNLLINC 120 +F + +YD + +++ +K K + F+ C K E + V++L+N Sbjct: 40 NF--------FSNYDAAKEMEEKYGIKTKCWNVADFEECRQAVKEIEEEFKKPVSILVNN 91 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T++ + R + D++NVN S M++ ++ M IVN Sbjct: 92 AGITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQMRNQDY-----------GRIVN 140 Query: 181 ISSI-LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 ISSI +G++ G + YSA+KA + FT+ LA E +NI I+PG + T+M+ Sbjct: 141 ISSINAQAGQV---GQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYI-ATEMVGA 196 Query: 240 LPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +P + + +I P EIA V L A Sbjct: 197 VPEDVLAKIINSIPKKRLGQPEEIARAVAFLVDENA 232 >3EZL-A nrPDB Length = 256 Score = 72.8 bits (177), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 71/267 (26%), Positives = 116/267 (43%), Gaps = 45/267 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A VTG GIG +ICQ+L + G ++ G S R + Q A+ Sbjct: 15 IAYVTGGMGGIGTSICQRLHKDGFR-VVAGCGPNSPRRVKW----------LEDQKALGF 63 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 DF Y S + D KQ + + + +++L+N AG+T+ Sbjct: 64 DF--------YASEGNV---GDWDSTKQAFDKVKAEVGE---------IDVLVNNAGITR 103 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + + T Q +++ N S +T I M+ +R W I+NISS+ Sbjct: 104 DVVFRKMTREDWQAVIDTNLTSLFNVTKQVIDGMV--ERGWGR---------IINISSV- 151 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G+ G + YS +KA + FT LA E+ + + T+SPG + GTDM++ + + Sbjct: 152 -NGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSPGYI-GTDMVKAIRPDVL 209 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYS 272 E + TI +P EI V L S Sbjct: 210 EKIVATIPVRRLGSPDEIGSIVAWLAS 236 >3VZS-A nrPDB Length = 257 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 69/261 (26%), Positives = 108/261 (41%), Gaps = 49/261 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A VTG GIG AICQ+L + G ++ G S R Sbjct: 16 IAYVTGGMGGIGTAICQRLAKDGFR-VVAGCGPNSPRR---------------------- 52 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYST--LFDPCNKWSNNERRYYVNLLINCAGL 123 WL+ + G ++ + ST FD V++LIN AG+ Sbjct: 53 -----EKWLEQQKALGFDFIASEGNVADWDSTKTAFDKVK-----SEVGEVDVLINNAGI 102 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 T++ + + T + +++ N S +T I M + R W IVNISS Sbjct: 103 TRDVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGM--ADRGWGR---------IVNISS 151 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 + +G+ G + YS +KA L FT LA E+ + + T+SPG + TDM++ + + Sbjct: 152 V--NGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYIA-TDMVKAIRQD 208 Query: 244 AKEMLERTIGASGTSAPAEIA 264 + + TI P EIA Sbjct: 209 VLDKIVATIPVKRLGLPEEIA 229 >1Q7C-A nrPDB Length = 244 Score = 70.1 bits (170), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 72/274 (26%), Positives = 117/274 (42%), Gaps = 57/274 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A+VTGA+RGIG+AI + L +G I G + A AI Sbjct: 7 IALVTGASRGIGRAIAETLAARGAKVI---------------------GTATSENGAQAI 45 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNE--RRYY--VNLLINCA 121 DY +G K + DP + S E R + V++L+N A Sbjct: 46 S--------DYLGANG----------KGLMLNVTDPASIESVLEKIRAEFGEVDILVNNA 87 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 G+T+++L +R + DI+ N S ++ ++ MMK + I+ I Sbjct: 88 GITRDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKKR-----------HGRIITI 136 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 S++ G M G + ++A+KA L F++ LA E+ R I ++PG ++ TDM + L Sbjct: 137 GSVV--GTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIE-TDMTRALS 193 Query: 242 VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + + A EIA V L S A Sbjct: 194 DDQRAGILAQVPAGRLGGAQEIANAVAFLASDEA 227 >4RZH-A nrPDB Length = 247 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 61/238 (25%), Positives = 106/238 (44%), Gaps = 45/238 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA+RGIGKA L G+ ++ + + + G + Q +A Sbjct: 8 VALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQANVA- 66 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + + Q T D ++ +++L+N AG+T+ Sbjct: 67 ---------------------NADEVDQLIKTTLDKFSR---------IDVLVNNAGITR 96 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++L +R Q ++++N T K M+K + SG+ I+NI+S+ Sbjct: 97 DTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKLMLKQK------SGR-----IINITSV- 144 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 +G M PG + YSA+KA + FT+ +A E+ R + ++PG + TDM +NL E Sbjct: 145 -AGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFI-ATDMTENLNAE 200 >3WOH-A nrPDB Length = 251 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 61/244 (25%), Positives = 113/244 (46%), Gaps = 49/244 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQ--SGLSYQRQCAI 63 VA+VTG +RG+G+A+ +L + G + I+ + +S + +G+++ G + +C + Sbjct: 13 VALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKET--QGEIERLGGTARSYRCDV 70 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + D ++ + + D P V++L+N AG+ Sbjct: 71 S-DAEQVTRCVKAVTAD------------------LGP------------VDILVNNAGI 99 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 ++ L+ +MN N C Y ++R SG +I+NISS Sbjct: 100 IRDGLAASIKDEDYDAVMNTNLKGAFLFIKAC--YFGFIRKR----SG-----SIINISS 148 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 + SG G + Y+++KA L T+ +A E+ RN+RC ++PGL+ TDM Q+L + Sbjct: 149 V--SGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNAVAPGLIA-TDMTQDLVDD 205 Query: 244 AKEM 247 +K + Sbjct: 206 SKRL 209 >3EMK-A nrPDB Length = 246 Score = 68.6 bits (166), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 75/270 (27%), Positives = 116/270 (42%), Gaps = 51/270 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGAT G+G+AI + L +G + G+ +E ++ A + G+ Sbjct: 10 ALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGE---------------R 54 Query: 67 FKKWPHWL-DYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 +P L D E+ L QK E V++L+N AG+T+ Sbjct: 55 IFVFPANLSDREAV---------KALGQKAE------------EEMGGVDILVNNAGITR 93 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L VR + ++ VN S +T MM+ RR I+NI+SI+ Sbjct: 94 DGLFVRMSDEDWDAVLTVNLTSVFNLTRELTHPMMR--RR---------NGRIINITSIV 142 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G PG + Y ASKA L F++ LA E+ RN+ I+PG ++ + M L + K Sbjct: 143 --GVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAPGFIE-SAMTGKLNEKQK 199 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + I A+IA V L S A Sbjct: 200 DAIMGNIPMKRMGVGADIAAAVVYLASDEA 229 >3F9I-A nrPDB Length = 249 Score = 68.2 bits (165), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 67/275 (24%), Positives = 114/275 (41%), Gaps = 65/275 (23%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 +++TGA+ GIG AI + L + G II GS +E ++ Sbjct: 17 SLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLG--------------------- 55 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNE------RRYYVNLLINC 120 LK Y+ + CN + E + +++L+ Sbjct: 56 ----------------------NALKDNYT--IEVCNLANKEECSNLISKTSNLDILVCN 91 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T ++L++R ++++N + + IK M+ Q+R+ I+N Sbjct: 92 AGITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKMI--QKRYGR---------IIN 140 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 ISSI+ G PG + Y ASKA L T+ L+ E+ R I ++PG +K +DM L Sbjct: 141 ISSIV--GIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGFIK-SDMTDKL 197 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + +E + + I P ++A V L S A Sbjct: 198 NEKQREAIVQKIPLGTYGIPEDVAYAVAFLASNNA 232 >4M8S-A nrPDB Length = 248 Score = 67.4 bits (163), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 50/162 (30%), Positives = 84/162 (51%), Gaps = 14/162 (8%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 +++L+N AG+T+++L +R + DIM VN S + ++ MMK QR +G+ Sbjct: 84 LDILVNNAGITRDNLLMRMKEEEWDDIMQVNLKSVFRASKAVLRGMMK-QR-----AGR- 136 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 I+NI+S++ G M G + Y+A+KA L F++ +A E+ R I ++PG + Sbjct: 137 ----IINITSVV--GVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCVAPGFID- 189 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 TDM + LP E ++ +IA+ V L S A Sbjct: 190 TDMTRALPEETRQTFTAQTALGRFGDAQDIADAVLFLASDQA 231 >2UVD-A nrPDB Length = 246 Score = 67.0 bits (162), Expect = 9e-12, Method: Compositional matrix adjust. Identities = 67/263 (25%), Positives = 111/263 (42%), Gaps = 47/263 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA+RGIG+AI L ++G + ++ + E Q+ + Sbjct: 6 VALVTGASRGIGRAIAIDLAKQGANVVVNYAGNE------------------QKANEVVD 47 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRY-YVNLLINCAGLT 124 + KK D ++ + D N + V++L+N AG+T Sbjct: 48 EIKKLGS--------------DAIAVRADVANAEDVTNMVKQTVDVFGQVDILVNNAGVT 93 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + ++N N T ++MM+ QR IVNI+S+ Sbjct: 94 KDNLLMRMKEEEWDTVINTNLKGVFLCTKAVSRFMMR-QRHGR----------IVNIASV 142 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G PG + Y A+KA + T+ A E+ RNI I+PG + TDM L Sbjct: 143 V--GVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNAIAPGFI-ATDMTDVLDENI 199 Query: 245 KEMLERTIGASGTSAPAEIAEEV 267 K + + I A+ +IA V Sbjct: 200 KAEMLKLIPAAQFGEAQDIANAV 222 >4DMM-A nrPDB Length = 269 Score = 63.5 bits (153), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 43/135 (31%), Positives = 73/135 (54%), Gaps = 14/135 (10%) Query: 109 ERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 ER +++L+N AG+T+++L +R Q ++++N + K M+K QR Sbjct: 102 ERWGRLDVLVNNAGITRDTLLLRMKRDDWQSVLDLNLGGVFLCSRAAAKIMLK-QR---- 156 Query: 169 LSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 SG+ I+NI+S++ G+M PG + YSA+KA + T+ +A E+ R I ++P Sbjct: 157 -SGR-----IINIASVV--GEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNAVAP 208 Query: 229 GLVKGTDMIQNLPVE 243 G + TDM L E Sbjct: 209 GFIA-TDMTSELAAE 222 Score = 31.2 bits (69), Expect = 0.55, Method: Compositional matrix adjust. Identities = 16/32 (50%), Positives = 21/32 (65%), Gaps = 4/32 (12%) Query: 1 MHYLP----VAIVTGATRGIGKAICQKLFQKG 28 M LP +A+VTGA+RGIG+AI +L G Sbjct: 21 MTALPLTDRIALVTGASRGIGRAIALELAAAG 52 >5VT6-A nrPDB Length = 269 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 70/276 (25%), Positives = 120/276 (43%), Gaps = 56/276 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA VTG G+G AI ++L G++ + S + + + L ++R Sbjct: 27 VAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERND---------HVSTWLMHERDAGR-- 75 Query: 66 DFKKWP-HWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYY--VNLLINCAG 122 DFK + D+ES C + + + V++LIN AG Sbjct: 76 DFKAYAVDVADFES-----------------------CERCAEKVLADFGKVDVLINNAG 112 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 +T+++ ++ T +M + + +T I M+ +RR+ IVNI Sbjct: 113 ITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQFIAGMV--ERRFGR---------IVNIG 161 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP- 241 S+ +G G + Y+++KA + FT+ LA E R I T+SPG + T M++ +P Sbjct: 162 SV--NGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTVSPGYLA-TAMVEAVPQ 218 Query: 242 --VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +EAK + + +G G P E+A + L S A Sbjct: 219 DVLEAKILPQIPVGRLGR--PDEVAALIAFLCSDDA 252 >4CQL-A nrPDB Length = 261 Score = 61.6 bits (148), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 63/269 (23%), Positives = 115/269 (42%), Gaps = 41/269 (15%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A+VTGA GIG+A+ +L +G ++ +DR Q + Sbjct: 13 LALVTGAGSGIGRAVSVRLAGEG----------ATVAACDLDRAAAQETVRLLG----GP 58 Query: 66 DFKKWPHWLDYESY--DGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 K+ P ++ ++ D E R L+Q + P +++++CAG+ Sbjct: 59 GSKEGPPRGNHAAFQADVSEARAARCLLEQVQACFSRP------------PSVVVSCAGI 106 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 TQ+ + + ++ VN +T + ++ + R +I+NISS Sbjct: 107 TQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSN----------GCRGSIINISS 156 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 I+ GK+ G + Y+ASKA + T+ A E+ IRC ++ PG + T M Q +P + Sbjct: 157 IV--GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIA-TPMTQKVPQK 213 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYS 272 + + I P ++A+ V L S Sbjct: 214 VVDKITEMIPMGHLGDPEDVADVVAFLAS 242 >3V2G-A nrPDB Length = 271 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 58/230 (25%), Positives = 95/230 (41%), Gaps = 46/230 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A VTG +RGIG AI ++L +G + + + + ER +++ + R AI D Sbjct: 34 AFVTGGSRGIGAAIAKRLALEGAAVAL--TYVNAAERAQAVVSEIEQ--AGGRAVAIRAD 89 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + D ++Q + +++L+N AG+ Sbjct: 90 NR------------------DAEAIEQAIRETVEALGG---------LDILVNSAGIWHS 122 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + TT + ++M VNF +P +++ R I+ I S L Sbjct: 123 APLEETTVADFDEVMAVNFRAPFVAIRSASRHLGDGGR-------------IITIGSNLA 169 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 + PG S+YSASKAAL+ T+ LA ++ PR I + PG TDM Sbjct: 170 E-LVPWPGISLYSASKAALAGLTKGLARDLGPRGITVNIVHPGSTD-TDM 217 >3OSU-A nrPDB Length = 246 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 67/276 (24%), Positives = 120/276 (43%), Gaps = 47/276 (17%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQR 59 M A+VTGA+RGIG++I +L ++G + + +KE E ++ + + S+ Sbjct: 1 MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAE-AVVEEIKAKGVDSFAI 59 Query: 60 QCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN 119 Q +A D E + ++ +L ++L+N Sbjct: 60 QANVA---------------DADEVKAMIKEVVSQFGSL----------------DVLVN 88 Query: 120 CAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 AG+T+++L +R + D+++ N CI Q+ P++ Q + I+ Sbjct: 89 NAGITRDNLLMRMKEQEWDDVIDTNLKGVFN----CI------QKATPQMLRQRS-GAII 137 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 N+SS++ G + PG + Y A+KA + T+ A E+ R I ++PG + +DM Sbjct: 138 NLSSVV--GAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFIV-SDMTDA 194 Query: 240 LPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 L E KE + I + +IA V L S A Sbjct: 195 LSDELKEQMLTQIPLARFGQDTDIANTVAFLASDKA 230 >4IS3-A nrPDB Length = 268 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 71/270 (26%), Positives = 109/270 (40%), Gaps = 44/270 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V I+TG TRGIG A + G I G T+E ++ TA+ QL+ + A Sbjct: 27 VTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVD-TAL--AQLKELYPEEEVLGFAP 83 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D S D + + QKY L +++IN AG+T Sbjct: 84 DLT---------SRDAV--MAAVGQVAQKYGRL----------------DVMINNAGITS 116 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++ R + + + IM++N ++ V C MK ++ I+N +S+ Sbjct: 117 NNVFSRVSEEEFKHIMDIN-VTGVFNGAWCAYQCMKDAKKG----------VIINTASV- 164 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G Y ASKA++ T L E+ +NIR ++PG+V TDM P E Sbjct: 165 -TGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIRVVGVAPGVVN-TDMTNGNPPEIM 222 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E + + P EIA L S A Sbjct: 223 EGYLKALPMKRMLEPEEIANVYLFLASDLA 252 >1SNY-A nrPDB Length = 267 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 39/125 (31%), Positives = 65/125 (52%), Gaps = 3/125 (2%) Query: 114 VNLLINCAGLTQESLSVRTTASQ-IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 +N+L N AG+ +S + SQ + D + N + P+ + C+ + K+ + Sbjct: 103 LNVLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPIMLAKACLPLLKKAAKANESQPMG 162 Query: 173 SARPTIVNISSILHSGKMKVPGTS-VYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 R I+N+SSIL S + G Y SK+AL+ T+ L+ ++ P+ I C ++ PG V Sbjct: 163 VGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAATKSLSVDLYPQRIMCVSLHPGWV 222 Query: 232 KGTDM 236 K TDM Sbjct: 223 K-TDM 226 >2GDZ-A nrPDB Length = 267 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 70/281 (24%), Positives = 119/281 (42%), Gaps = 59/281 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA +GIG+A + L KG + A+ L++G+ QC A+ Sbjct: 9 VALVTGAAQGIGRAFAEALLLKG-------------AKVALVDWNLEAGV----QCKAAL 51 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + P + D D+ L+ + + D + +++L+N AG+ Sbjct: 52 HEQFEPQKTLFIQCD----VADQQQLRDTFRKVVDHFGR---------LDILVNNAGVNN 98 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 E +T + +N +S ++ T + + YM K G+ I+N+SS+ Sbjct: 99 EKNWEKT--------LQINLVSVISGTYLGLDYMSKQN------GGEGG--IIINMSSL- 141 Query: 186 HSGKMKVPGTSVYSASKAALSRFTE--VLAAEMEPRNIRCFTISPGLVKGTDMIQNLP-- 241 +G M V VY ASK + FT LAA + +R I PG V T +++++ Sbjct: 142 -AGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVN-TAILESIEKE 199 Query: 242 ------VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTAL 276 +E K+ ++ I G P IA + +L AL Sbjct: 200 ENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDAL 240 >2NWQ-A nrPDB Length = 272 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 64/275 (23%), Positives = 118/275 (42%), Gaps = 47/275 (17%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 H +TGAT G G+A ++ + G S ++ G +E ++ A G+L + Sbjct: 19 HMSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALA---GELSA-------- 67 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 + P LD + D P ++++TL LIN A Sbjct: 68 ----KTRVLPLTLDVRDRAAMSAAVDNLP--EEFATLRG----------------LINNA 105 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRW-PELSGQSARPTIVN 180 GL ++ T +Q D+ + + TM + IK ++ S R P L A +IVN Sbjct: 106 GL-----ALGTDPAQSCDLDDWD-----TMVDTNIKGLLYSTRLLLPRLIAHGAGASIVN 155 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 + S+ +GK PG+ VY +KA + +F+ L +++ +R + PGL + + Sbjct: 156 LGSV--AGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPGLCESEFSLVRF 213 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + ++T + P +IAE ++ + ++ A Sbjct: 214 GGD-QARYDKTYAGAHPIQPEDIAETIFWIMNQPA 247 >4MOW-A nrPDB Length = 256 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 56/227 (24%), Positives = 101/227 (44%), Gaps = 48/227 (21%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VAIVTGA++GIG AI + L +G + ++ S+K + A+ ++G R A+ Sbjct: 16 VAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGAD--AVVSAITEAG---GRAVAVG 70 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D K ++ T + + +++L+N +G+ Sbjct: 71 GDVSKAADA------------------QRIVDTAIETYGR---------LDVLVNNSGVY 103 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + T + + N + T +K++ G+ A +I+NISS+ Sbjct: 104 EFAPIEAITEEHYRRQFDTNVFGVLLTTQAAVKHL-----------GEGA--SIINISSV 150 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 + S + P ++VYS +K A+ T VLA E+ PR IR I+PG++ Sbjct: 151 VTS--ITPPASAVYSGTKGAVDAITGVLALELGPRKIRVNAINPGMI 195 >4IIN-A nrPDB Length = 271 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 44/156 (28%), Positives = 75/156 (48%), Gaps = 14/156 (8%) Query: 117 LINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARP 176 L+N AG+ ++ L+++ +++ N S +K M KS+ Sbjct: 111 LVNNAGVVRDKLAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRF-----------G 159 Query: 177 TIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 ++VN++SI+ G+ G + YSASK + ++ A E RNIR +++PG ++ TDM Sbjct: 160 SVVNVASII--GERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRFNSVTPGFIE-TDM 216 Query: 237 IQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYS 272 NL E K + I + + E+AE V L S Sbjct: 217 NANLKDELKADYVKNIPLNRLGSAKEVAEAVAFLLS 252 >4NBT-A nrPDB Length = 240 Score = 57.8 bits (138), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 66/278 (23%), Positives = 119/278 (42%), Gaps = 69/278 (24%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA++TG +G+G+AI ++G I A D G L +Y + Sbjct: 8 VAVITGGAKGLGQAIALAYAEEGAKVI------------AGDLGDL----TYSHPNVEGM 51 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 +L+ G+E F Y ++ D K +++L+N AG+T+ Sbjct: 52 -------YLNVTDVTGVEKF---------YQSVIDKYGK---------IDILVNNAGITK 86 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++++ + T +Q +++VN +T + P++ + +I+NISS++ Sbjct: 87 DAMTRKMTEAQWDAVIDVNLKGVFNLTRLV----------GPQMQ-TNGYGSIINISSVV 135 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAE--MEPRNIRCFTISPGLVKGTDMIQNLPVE 243 G G + Y+A+KA + T A E ++ N+R I+PG + TD+++ +P + Sbjct: 136 --GVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIM-TDILKTVPQD 192 Query: 244 ------AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 A ML R P EIA+ L S A Sbjct: 193 LLDKFAALTMLNR------LGQPEEIAKVALFLASDDA 224 >2O23-A nrPDB Length = 265 Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 61/243 (25%), Positives = 100/243 (41%), Gaps = 51/243 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA++TG G+G A ++L +G S ++L E A G C A Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN---------NCVFA- 63 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 P + E K + L K+ V++ +NCAG+ Sbjct: 64 -----PADVTSE--------------KDVQTALALAKGKFGR------VDVAVNCAGIAV 98 Query: 126 ESLSVRTTASQ------IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 S + Q Q +++VN M + + M +++ P+ GQ R I+ Sbjct: 99 ASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQNE---PDQGGQ--RGVII 153 Query: 180 NISSIL-HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 N +S+ G++ G + YSASK + T +A ++ P IR TI+PGL GT ++ Sbjct: 154 NTASVAAFEGQV---GQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF-GTPLLT 209 Query: 239 NLP 241 +LP Sbjct: 210 SLP 212 >1AE1-A nrPDB Length = 273 Score = 55.5 bits (132), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 55/225 (24%), Positives = 97/225 (43%), Gaps = 44/225 (19%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG ++GIG AI ++L GL + ++ + +L L R+ + ++ Sbjct: 24 ALVTGGSKGIGYAIVEEL--AGLGARVYTCSR--------NEKELDECLEIWREKGLNVE 73 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 S + +R L Q + +FD +N+L+N AG+ Sbjct: 74 ----------GSVCDLLSRTERDKLMQTVAHVFDG-----------KLNILVNNAGVVIH 112 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T IM NF + ++ I + SQ ++ +SSI Sbjct: 113 KEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQN-----------GNVIFLSSI-- 159 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 +G +P S+YSASK A+++ T+ LA E NIR +++PG++ Sbjct: 160 AGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVI 204 >4HP8-A nrPDB Length = 247 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 65/250 (26%), Positives = 107/250 (42%), Gaps = 61/250 (24%) Query: 7 AIVTGATRGIGKAICQKLFQKG--LSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A+VTGA G+G+AI L G + C + E+++ A D G A+ Sbjct: 12 ALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGN---------ASALL 62 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 IDF PL K S F ++L+N AG+ Sbjct: 63 IDFAD--------------------PLAAKDS--FTDAG----------FDILVNNAGII 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + SV + ++M+VN + T K ++ R SG+ +VNI+S+ Sbjct: 91 RRADSVEFSELDWDEVMDVNLKALFFTTQAFAKELLAKGR-----SGK-----VVNIASL 140 Query: 185 L-HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 L G ++VP Y+A+K ++ T++LA E + I I+PG ++ T+ + L + Sbjct: 141 LSFQGGIRVPS---YTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYIE-TNNTEALRAD 196 Query: 244 A---KEMLER 250 A K +LER Sbjct: 197 AARNKAILER 206 >4Z9Y-A nrPDB Length = 253 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 63/254 (24%), Positives = 107/254 (42%), Gaps = 62/254 (24%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGST----KESIER-TAIDRGQLQSGLSYQRQ 60 VA++TG G+G+ + L Q G C I+G K++IE+ TA+ R R Sbjct: 12 VALITGCDTGLGQGMAIGLAQAG--CDIVGVNIVEPKDTIEKVTALGR----------RF 59 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 ++ D L +K F +V++L+N Sbjct: 60 LSLTADMSN---------------VSGHAELVEKAVAEFG------------HVDILVNN 92 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+ + ++ + D+MN+N S M+ + +K Q I+N Sbjct: 93 AGIIRREDAIEFSEKNWDDVMNLNIKSVFFMSQTVARQFIK----------QGKGGKIIN 142 Query: 181 ISSIL-HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 I+S+L G ++VP Y+ASK+A+ T ++A E I I+PG + T+ Q Sbjct: 143 IASMLSFQGGIRVPS---YTASKSAVMGVTRLMANEWAKHGINVNAIAPGYMA-TNNTQQ 198 Query: 240 LPVE---AKEMLER 250 L + +KE+L+R Sbjct: 199 LRADEERSKEILDR 212 >5B1Y-A nrPDB Length = 270 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 61/245 (24%), Positives = 109/245 (44%), Gaps = 46/245 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESI-ERTAIDRGQLQSGLSYQRQCAIAI 65 A+VTG +RGIG+A + ++G S +I ++ + E+TA + +L S +Y + Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVR----- 80 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 +D D + R E ++N+L+N AG+ Q Sbjct: 81 --------VDVGDPDSVTEMSSRV------------------GELIPHLNVLVNAAGVLQ 114 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 T+ S+ ++ + VN +T + + + K+ +W +IVN++SI Sbjct: 115 LGGIEETSISEWEETLRVNLTGVYLVTKLLLPLLRKA--KW---------ASIVNVASIA 163 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 V G + YSASKA + T+ LA ++ IR ++P V+ TDM ++ ++ Sbjct: 164 GETGNVVAGVA-YSASKAGVIGLTKRLAVQLAGYGIRVNAVAPSFVE-TDMTRSF-LDTP 220 Query: 246 EMLER 250 E ER Sbjct: 221 EKRER 225 >2CFC-A nrPDB Length = 250 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 59/236 (25%), Positives = 96/236 (40%), Gaps = 48/236 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VAIVTGA+ G G AI + +G L + E++E TA Sbjct: 4 VAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETA-------------------- 43 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT- 124 HW Y + + R + + + E+ +++L+N AG+T Sbjct: 44 ----RTHWHAYAD----KVLRVRADVADEGDV---NAAIAATMEQFGAIDVLVNNAGITG 92 Query: 125 -QESLSVRTT-ASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 E+ + TT Q +M VN + +M+ L G IVNI+ Sbjct: 93 NSEAGVLHTTPVEQFDKVMAVNVRGIFLGCRAVLPHML--------LQGAG---VIVNIA 141 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 S+ + + PG S Y+ SK A+ + T+ +A + IRC + PG+++ T M Q Sbjct: 142 SV--ASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNAVCPGMIE-TPMTQ 194 >2AE2-A nrPDB Length = 260 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 64/248 (25%), Positives = 105/248 (42%), Gaps = 47/248 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG +RGIG I ++L LG++ + R ++ +L L+ R + Sbjct: 12 ALVTGGSRGIGYGIVEELAS-------LGASVYTCSR---NQKELNDCLTQWR----SKG 57 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 FK D S +R L + F +N+L+N AG+ Sbjct: 58 FKVEASVCDLSSR------SERQELMNTVANHFHG-----------KLNILVNNAGIVIY 100 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T IM++NF + ++ + ++ S+R +V ISS+ Sbjct: 101 KEAKDYTVEDYSLIMSINFEAAYHLSVLAHPFLKASER-----------GNVVFISSV-- 147 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT--DMIQNLPVEA 244 SG + VP +VY A+K A+ + T LA E NIR + PG++ + +M P E Sbjct: 148 SGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNGVGPGVIATSLVEMTIQDP-EQ 206 Query: 245 KEMLERTI 252 KE L + I Sbjct: 207 KENLNKLI 214 >4NBV-A nrPDB Length = 246 Score = 54.3 bits (129), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 39/151 (25%), Positives = 76/151 (50%), Gaps = 14/151 (9%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 V++L+N AG+T+++ + T +Q +++VN +K + + L + Sbjct: 83 VDILVNNAGITKDARLAKMTEAQFDAVIDVN-----------LKGVFNCAQAVAGLMTEQ 131 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 + I+N SS++ G G + Y+ASK + FT+ A E+ P+ +R + PG V Sbjct: 132 GKGVILNASSVV--GLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVNAVCPGFVN- 188 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIA 264 T+++Q +P + + + + + PAEIA Sbjct: 189 TEILQTVPDKVLDGMTSSCWLRRLAEPAEIA 219 >2NM0-A nrPDB Length = 253 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 45/162 (27%), Positives = 74/162 (45%), Gaps = 14/162 (8%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 V +LI AG+T++ L +R + ++ N + + M+++++ Sbjct: 88 VEVLIANAGVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLRAKK--------- 138 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 +V ISS++ G + G + Y+ASKA L F LA E+ RNI ++PG V Sbjct: 139 --GRVVLISSVV--GLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVD- 193 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 TDM + L E + + + + P EIA V L S A Sbjct: 194 TDMTKVLTDEQRANIVSQVPLGRYARPEEIAATVRFLASDDA 235 >5OJG-A nrPDB Length = 260 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 57/242 (23%), Positives = 94/242 (38%), Gaps = 58/242 (23%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VAIVT AT+GIG AI ++L +G S +I +++++ Sbjct: 12 VAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVD----------------------- 48 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLK----QKYSTLFDPCNKWSNNERRYY--VNLLIN 119 + IEY K++ K + D K + + + +N+L+N Sbjct: 49 --------------EAIEYLKNKGLTKVAGIAGHIASTDDQKKLVDFTLQKFGKINILVN 94 Query: 120 CAGLTQESLSVRTTASQIQD-IMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTI 178 G+ + + Q+ D + VN + MT + P ++ + I Sbjct: 95 NHGINPAFGHILEVSDQVWDKLFEVNVKAGFQMTKLV----------HPHIAKEGGGAII 144 Query: 179 VNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 N S +S PG + Y +K L T LA + NIR I+PG++K T M Q Sbjct: 145 FNAS---YSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIK-TKMSQ 200 Query: 239 NL 240 L Sbjct: 201 VL 202 >1E3W-A nrPDB Length = 261 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 44/171 (25%), Positives = 79/171 (46%), Gaps = 32/171 (18%) Query: 98 LFDPCNKWSNNERRYY----------VNLLINCAGLTQESLSVRT---------TASQIQ 138 +F P N S E + +++ +NCAG+ +++++T T Q Sbjct: 59 IFAPANVTSEKEVQAALTLAKEKFGRIDVAVNCAGI---AVAIKTYHEKKNQVHTLEDFQ 115 Query: 139 DIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL-HSGKMKVPGTSV 197 ++NVN + + + M +++ P+ GQ R I+N +S+ G++ G + Sbjct: 116 RVINVNLIGTFNVIRLVAGVMGQNE---PDQGGQ--RGVIINTASVAAFEGQV---GQAA 167 Query: 198 YSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEML 248 YSASK + T +A ++ P IR TI+PGL T ++ LP + L Sbjct: 168 YSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFA-TPLLTTLPDTVRNFL 217 >2ZAT-A nrPDB Length = 260 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 56/242 (23%), Positives = 93/242 (38%), Gaps = 74/242 (30%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQS-GLSY------- 57 VA+VT +T GIG AI ++L Q G ++ +E+++RT LQ GLS Sbjct: 16 VALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTV---ATLQGEGLSVTGTVCHV 72 Query: 58 ------QRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNK-WSNNER 110 +R A+A++ + G++ + + + D + W Sbjct: 73 GKAEDRERLVAMAVNL-----------HGGVDILVSNAAVNPFFGNIIDATEEVW----- 116 Query: 111 RYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELS 170 I++VN + V MT + PE+ Sbjct: 117 ---------------------------DKILHVNVKATVLMTKAVV----------PEME 139 Query: 171 GQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGL 230 + ++ +SS+ P Y+ SK AL T+ LA E+ PRNIR ++PGL Sbjct: 140 KRGGGSVLI-VSSV--GAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGL 196 Query: 231 VK 232 +K Sbjct: 197 IK 198 >3WTC-A nrPDB Length = 262 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 60/250 (24%), Positives = 101/250 (40%), Gaps = 45/250 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A VTGA +GIGKAI +L + G I+L ++++ TA + L +R A+ Sbjct: 10 IAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALG-----RRAVALTA 64 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D + STL D +++++N AG+ Q Sbjct: 65 DISNRDQF---------------------RSTLADAAKTLGG------LDIMVNNAGICQ 97 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + ++I+ I ++N + M + + E + + I+N SI Sbjct: 98 VKPILDIEPAEIEKIFSINVQG-------VLWGMQAAATLFKE---KGTKGKIINACSI- 146 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G P YSA+K A+ T+ A E+ I + PG+V GTDM + Sbjct: 147 -AGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITVNSYCPGIV-GTDMWVTIDKRMA 204 Query: 246 EMLERTIGAS 255 E+ IGA+ Sbjct: 205 EITGTEIGAT 214 >3O4R-A nrPDB Length = 261 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 60/229 (26%), Positives = 97/229 (42%), Gaps = 48/229 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQS-GLSYQRQCAIA 64 VA+VT +T GIG AI ++L Q G ++ ++++++ LQ GLS Sbjct: 17 VALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAV---ATLQGEGLSVTGTVC-- 71 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 H + +DR L L +++L++ A + Sbjct: 72 -------H---------VGKAEDRERLVATAVKLHG------------GIDILVSNAAVN 103 Query: 125 QESLSVRTTASQIQD-IMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 S+ ++ D +++N +P MT + M K G S +V +SS Sbjct: 104 PFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKR-------GGGS----VVIVSS 152 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 I + PG S Y+ SK AL T+ LA E+ PRNIR ++PGL+K Sbjct: 153 I--AAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIK 199 >5IZ4-A nrPDB Length = 271 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 69/276 (25%), Positives = 112/276 (40%), Gaps = 52/276 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 PV ++TG+ GIG A + Q G S + +G+ +S A L Q A Sbjct: 15 PVCVITGSASGIGAATALRFAQAGWS-VAIGNFDDSTRDAASTVEALCRDAGAQTLIFDA 73 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D K D + ++ R W ++ LINCAG T Sbjct: 74 -DVGK-----DADCRHAVDMVASR----------------WQR------IDALINCAGTT 105 Query: 125 QESLSVRTTASQIQD-----IMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 + + QI D + VN + MT + + +S + + ++V Sbjct: 106 R--VIPHNAFDQIDDFEFERVYRVNLIGLYQMTRAAVPLLRES-------ASATRSTSVV 156 Query: 180 NISSILHSGKMKVPGTSV-YSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 N+SS+ + G+S+ Y+ASK A++ T LA + P +IR ++PG+V +++ Sbjct: 157 NVSSL---AGLNGTGSSIAYAASKGAVNTLTLSLARNLAP-HIRVNALAPGMVDDGLLLR 212 Query: 239 NLPVEAKEMLERTIGASG----TSAPAEIAEEVWSL 270 L A + + + S S PAEIAE W L Sbjct: 213 VLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL 248 >4K6F-A nrPDB Length = 255 Score = 50.4 bits (119), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 67/279 (24%), Positives = 111/279 (39%), Gaps = 62/279 (22%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A+VTG G+G+A+ +L G ++ S T DR A Sbjct: 13 IAVVTGGMGGLGEAVSIRLNDAGHRVVV----TYSPNNTGADR-------WLTEMHAAGR 61 Query: 66 DFKKWPHWLDYESYDGIE-----YFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 +F +P +D +D + +D P V++L+N Sbjct: 62 EFHAYP--VDVADHDSCQQCIEKIVRDVGP-----------------------VDILVNN 96 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T++ + ++ N S MT M+ +R W IVN Sbjct: 97 AGITRDMTLRKLDKVNWDAVIRTNLDSVFNMTKPVCDGMV--ERGWGR---------IVN 145 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 ISS+ +G G + Y+A+KA + FT+ LA E+ + + T+SPG + T M+ + Sbjct: 146 ISSV--NGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNTVSPGYLA-TKMVTAI 202 Query: 241 PVEAKEMLERT----IGASGTSAPAEIAEEVWSLYSRTA 275 P +++L+ I A P E+A V L S A Sbjct: 203 P---QDILDTKILPQIPAGRLGKPEEVAALVAYLCSEEA 238 >3RKU-A nrPDB Length = 287 Score = 50.1 bits (118), Expect = 9e-07, Method: Compositional matrix adjust. Identities = 38/120 (31%), Positives = 59/120 (49%), Gaps = 14/120 (11%) Query: 114 VNLLINCAGLTQESLSVRTTASQ-IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 +++L+N AG S V A++ IQD+ + N + + +T + SG Sbjct: 116 IDILVNNAGKALGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKN------SGD 169 Query: 173 SARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 IVN+ SI +G+ P S+Y ASK A+ FT+ L E+ IR I+PGLV+ Sbjct: 170 -----IVNLGSI--AGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAPGLVE 222 >3OEC-A nrPDB Length = 317 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 54/234 (23%), Positives = 96/234 (41%), Gaps = 33/234 (14%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA +TGA RG G+ +L Q G + AID + Q L Y + Sbjct: 48 VAFITGAARGQGRTHAVRLAQDGADIV------------AIDLCRQQPNLDYAQGSPE-- 93 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + K+ ++ + I D L + + + ++ ++++L++ G++ Sbjct: 94 ELKETVRLVEEQGRRIIARQADVRDLASLQAVVDEALAEFG------HIDILVSNVGISN 147 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + V T Q DI+ N + + M++ GQ +++ +SS + Sbjct: 148 QGEVVSLTDQQWSDILQTNLIGAWHACRAVLPSMIER--------GQGG--SVIFVSSTV 197 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 G PG S Y+ASK + LA E+ NIR +++PG V T+M N Sbjct: 198 --GLRGAPGQSHYAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVN-TEMALN 248 >3U5T-A nrPDB Length = 267 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 51/233 (21%), Positives = 94/233 (40%), Gaps = 54/233 (23%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VAIVTGA+RGIG AI +L G + +I + K + + + G + Q Sbjct: 24 METNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQ 83 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 ++ D +++ ++T E V++L+N Sbjct: 84 ADVS----------------------DPAAVRRLFATA---------EEAFGGVDVLVNN 112 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+ + T + ++ VN + ++ +R + G+ I+N Sbjct: 113 AGIMPLTTIAETGDAVFDRVIAVNLKG-------TFNTLREAAQRL-RVGGR-----IIN 159 Query: 181 ISS----ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 +S+ +LH P +Y+A+KA + T VL+ E+ R+I ++PG Sbjct: 160 MSTSQVGLLH------PSYGIYAAAKAGVEAMTHVLSKELRGRDITVNAVAPG 206 >1K2W-A nrPDB Length = 256 Score = 47.4 bits (111), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 51/227 (22%), Positives = 91/227 (40%), Gaps = 47/227 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TG+ RGIG+A + ++G I E+ TA + G CAIA+D Sbjct: 8 ALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPA--------ACAIALD 59 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 D+ + + + L D +W + +++L+N A L Sbjct: 60 ------------------VTDQASIDRCVAELLD---RWGS------IDILVNNAALFDL 92 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + V T + +N + +MM++ R G+ + I+N++S Sbjct: 93 APIVEITRESYDRLFAINVSGTL--------FMMQAVARAMIAGGRGGK--IINMAS--Q 140 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 +G+ VY A+KAA+ T+ + I I+PG+V G Sbjct: 141 AGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAIAPGVVDG 187 >1GEE-A nrPDB Length = 261 Score = 47.4 bits (111), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 35/136 (25%), Positives = 61/136 (44%), Gaps = 19/136 (13%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 ++++IN AGL S + S +++ N + IKY +++ Sbjct: 86 LDVMINNAGLENPVSSHEMSLSDWNKVIDTNLTGAFLGSREAIKYFVEND---------- 135 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 + T++N+SS+ K+ P Y+ASK + TE LA E P+ IR I PG + Sbjct: 136 IKGTVINMSSVHE--KIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAI-- 191 Query: 234 TDMIQNLPVEAKEMLE 249 N P+ A++ + Sbjct: 192 -----NTPINAEKFAD 202 >4DBZ-A nrPDB Length = 281 Score = 47.4 bits (111), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 55/227 (24%), Positives = 90/227 (39%), Gaps = 43/227 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGAT GIG I ++L ++GL + +E + T L R+ + Sbjct: 28 VALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTT----------LKELREAGVEA 77 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D + D S P ++ + + ER V++L+N AG Sbjct: 78 DGRTC----DVRSV---------PEIEALVAAVV---------ERYGPVDVLVNNAGRPG 115 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + D++ N +T K ++K+ +G+ IVNI+S Sbjct: 116 GGATAELADELWLDVVETNLTGVFRVT----KQVLKAGGMLERGTGR-----IVNIAST- 165 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 GK + + YSASK + FT+ L E+ I + PG V+ Sbjct: 166 -GGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAVCPGFVE 211 >3D3W-A nrPDB Length = 244 Score = 47.0 bits (110), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 61/250 (24%), Positives = 94/250 (37%), Gaps = 64/250 (25%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTGA +GIG+ Q L G + + T+ ++ S R+C Sbjct: 11 LVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD-------------SLVREC------ 51 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYY----VNLLINCAGL 123 P ++ L D W ER V+LL+N A + Sbjct: 52 ---------------------PGIEPVCVDLGD----WEATERALGSVGPVDLLVNNAAV 86 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + T VN + + ++ I + ++ R P IVN+SS Sbjct: 87 ALLQPFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIA--RGVPG--------AIVNVSS 136 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--- 240 + V SVY ++K AL T+V+A E+ P IR ++P +V T M Q Sbjct: 137 --QCSQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVM-TSMGQATWSD 193 Query: 241 PVEAKEMLER 250 P +AK ML R Sbjct: 194 PHKAKTMLNR 203 >6CI9-A nrPDB Length = 259 Score = 47.0 bits (110), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 58/245 (23%), Positives = 97/245 (39%), Gaps = 50/245 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 AIVTG ++GIG+ I + G+ +I G ++ ++RT D LS R A+ Sbjct: 12 AIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVAD-------LSGTRGKVTAV- 63 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 D + R + + S R ++++ AG+ Sbjct: 64 -----------RADVTDPEDARRTVAETVS-------------RHGGLDIVCANAGIFPS 99 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 T I+ ++ VNF V Y++++ + SG +V SSI Sbjct: 100 GRLEDLTPDDIEQVLGVNFKGTV--------YIVQAALQALTASGHG---RVVVTSSI-- 146 Query: 187 SGKM-KVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G + PG S Y ASKAA F A E+ P+ I + PG + M + L + Sbjct: 147 TGPITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNI----MTEGLDEMGQ 202 Query: 246 EMLER 250 + L++ Sbjct: 203 DYLDQ 207 >2X9N-A nrPDB Length = 288 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 66/279 (23%), Positives = 118/279 (42%), Gaps = 41/279 (14%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 P A+VTGA + IG+AI KL Q G +I ++ E+ A + + +S + Q + Sbjct: 24 PAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADL 83 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + P + + F C+ NN +Y L+ G Sbjct: 84 T-NSNVLPASCE--------------EIINSCFRAFGRCDVLVNNASAFYPTPLVQ--GD 126 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 +++ + +T +Q+ +++ N ++P +T + + + + P + S+ +IVN+ Sbjct: 127 HEDNSNGKTVETQVAELIGTNAIAPFLLT---MSFAQRQKGTNPNCT--SSNLSIVNLCD 181 Query: 184 ILHSGKMKVP--GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 + + P S+Y+ K AL T+ A E+ P IR ++PG + LP Sbjct: 182 AM----VDQPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPG-------VSLLP 230 Query: 242 V----EAKEMLERTIGASGTSAPAE-IAEEVWSLYSRTA 275 V E K+ R + A AE IA+ V L S +A Sbjct: 231 VAMGEEEKDKWRRKVPLGRREASAEQIADAVIFLVSGSA 269 >1NFF-A nrPDB Length = 260 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 44/159 (27%), Positives = 78/159 (49%), Gaps = 19/159 (11%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 +++L+N AG+ ++ Q I++VN T + I+ ++K + ++ Sbjct: 82 LHVLVNNAGILNIGTIEDYALTEWQRILDVNL----TGVFLGIRAVVKPMK-------EA 130 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 R +I+NISSI G Y+A+K A+ T+ A E+ P IR +I PGLVK Sbjct: 131 GRGSIINISSI--EGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHPGLVK- 187 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYS 272 T M +P +++ + +G + + P E++ V L S Sbjct: 188 TPMTDWVP---EDIFQTALGRA--AEPVEVSNLVVYLAS 221 >1CYD-A nrPDB Length = 244 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 60/247 (24%), Positives = 103/247 (41%), Gaps = 56/247 (22%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGA +GIG+ + L G + ++ RT D +S ++C I+ Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVV-------AVTRTNSDL------VSLAKECP-GIE 55 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 P +D +D E K P V+LL+N A L Sbjct: 56 ----PVCVDLGDWDATE----------KALGGIGP------------VDLLVNNAALVIM 89 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T +VN S ++ + + M+ R P +IVN+SS++ Sbjct: 90 QPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMI--NRGVPG--------SIVNVSSMV- 138 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL---PVE 243 + P YS++K A++ T+ +A E+ P IR +++P +V TDM + + P Sbjct: 139 -AHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVVL-TDMGKKVSADPEF 196 Query: 244 AKEMLER 250 A+++ ER Sbjct: 197 ARKLKER 203 >2B4Q-A nrPDB Length = 276 Score = 45.1 bits (105), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 59/226 (26%), Positives = 88/226 (38%), Gaps = 45/226 (19%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC-AIA 64 +A+VTG +RGIG+ I Q L + G I E+ TA LS C AI Sbjct: 31 IALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATR-------LSAYGDCQAIP 83 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D E R L Q E +++L+N AG + Sbjct: 84 ADLSS-------------EAGARR--LAQAL------------GELSARLDILVNNAGTS 116 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPT-IVNISS 183 + S + +M +N VT CI+ ++ RR S + P ++NI S Sbjct: 117 WGAALESYPVSGWEKVMQLN----VTSVFSCIQQLLPLLRR----SASAENPARVINIGS 168 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 + M + Y SKAAL + + +LA E+ +I I+PG Sbjct: 169 VAGISAMGEQAYA-YGPSKAALHQLSRMLAKELVGEHINVNVIAPG 213 >4DA9-A nrPDB Length = 280 Score = 44.3 bits (103), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 59/127 (46%), Gaps = 17/127 (13%) Query: 114 VNLLINCAGLT----QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 ++ L+N AG+ + L ++ I+ VN V T +K M+ S R Sbjct: 108 IDCLVNNAGIASIVRDDFLDLKP--ENFDTIVGVNLRGTVFFTQAVLKAMLASDAR---- 161 Query: 170 SGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 A +I+NI+S+ S M P Y SKA L+ F++ LA + I F + PG Sbjct: 162 ----ASRSIINITSV--SAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVFEVRPG 215 Query: 230 LVKGTDM 236 +++ +DM Sbjct: 216 IIR-SDM 221 >5JS6-A nrPDB Length = 274 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 14/98 (14%) Query: 132 TTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMK 191 T+A + ++ +N + T+T + + Y+ KSQ ++NISS++ G + Sbjct: 104 TSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG------------NVINISSLV--GAIG 149 Query: 192 VPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 Y A+K A++ T+ LA + P +R ISPG Sbjct: 150 QAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPG 187 >1UZM-A nrPDB Length = 247 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 56/268 (20%), Positives = 100/268 (37%), Gaps = 57/268 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG RGIG AI Q+L G + A+ Sbjct: 19 LVTGGNRGIGLAIAQRLAADG------------------------------HKVAVTHRG 48 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 P L D D + + ++ + E + V +L++ AGL+ ++ Sbjct: 49 SGAPKGLFGVEVD----VTDSDAVDRAFTAV---------EEHQGPVEVLVSNAGLSADA 95 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 +R T + + ++N N + + M +++ ++ I S+ S Sbjct: 96 FLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKF-----------GRMIFIGSV--S 142 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G + + Y+ASKA + +A E+ N+ ++PG + TDM + L ++ Sbjct: 143 GLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYID-TDMTRALDERIQQG 201 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I A PAE+A V L S A Sbjct: 202 ALQFIPAKRVGTPAEVAGVVSFLASEDA 229 >6NRP-A nrPDB Length = 263 Score = 43.9 bits (102), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 57/245 (23%), Positives = 105/245 (42%), Gaps = 59/245 (24%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG++RGIGKAI +L + G + ++++ + ++Q+ Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQ--EIQA-------------L 72 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 + H+L ++ +R ++Q + + + +++N AGLT + Sbjct: 73 GQNSHYLMFD-------VNERQTVQQIL--------EQDVEQHGGFYGVVLN-AGLTHDG 116 Query: 128 LSVRTTASQIQDIMNV------NFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 T ++++ N + P+ M I ++ K R IV + Sbjct: 117 AFPALTDQDWDEVISTSLDGFYNVLKPLIMPMI---HLRKGGR-------------IVTL 160 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 SS+ SG M G YSA+KA L T+ LA E+ R I ++PGL++ T+M+ + Sbjct: 161 SSV--SGIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVAPGLIE-TEMVTD-- 215 Query: 242 VEAKE 246 E KE Sbjct: 216 -EVKE 219 >1X1T-A nrPDB Length = 260 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 53/228 (23%), Positives = 88/228 (38%), Gaps = 45/228 (19%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILG-STKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTG+T GIG I L +G ++ G IE+ +++GL+ Q + Sbjct: 6 VAVVTGSTSGIGLGIATALAAQGADIVLNGFGDAAEIEK-------VRAGLAAQHGVKVL 58 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 YDG + K + L D + + +++L+N AG+ Sbjct: 59 --------------YDGADLSKG-----EAVRGLVDNAVR-----QMGRIDILVNNAGIQ 94 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +L + I+ +N + T + +M K I+NI+S Sbjct: 95 HTALIEDFPTEKWDAILALNLSAVFHGTAAALPHMKKQ-----------GFGRIINIASA 143 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 G + S Y A+K + FT+V A E + I I PG V+ Sbjct: 144 --HGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITANAICPGWVR 189 >1B15-A nrPDB Length = 254 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 54/119 (45%), Gaps = 18/119 (15%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 V++LIN AG+ + QI+ + +NF V T + + W + G Sbjct: 85 VDILINGAGILDDH--------QIERTIAINFTGLVNTTTAILDF-------WDKRKGGP 129 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 I NI S+ +G + VYSASKAA+ FT LA + ++I+PG+ + Sbjct: 130 GG-IIANICSV--TGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGVTAYSINPGITR 185 >2BFA-A nrPDB Length = 288 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 58/258 (22%), Positives = 105/258 (40%), Gaps = 49/258 (18%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQR-QCA 62 +PVA+VTGA + +G++I + L +G + + R+A + L + L+ +R A Sbjct: 6 VPVALVTGAAKRLGRSIAEGLHAEGYAVCL------HYHRSAAEANALSATLNARRPNSA 59 Query: 63 IAI-----DFKKWPHWLDYESYDG---IEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYV 114 I + + P DG + F L T + C+ NN +Y Sbjct: 60 ITVQADLSNVATAP----VSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYP 115 Query: 115 NLLIN--------CAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRW 166 L+ C G +E++ T D+ N ++P +++K+ Sbjct: 116 TPLLRNDEDGHEPCVG-DREAMETATA-----DLFGSNAIAPY--------FLIKAFAH- 160 Query: 167 PELSGQSARPTIVNISSILHSGKMK---VPGTSVYSASKAALSRFTEVLAAEMEPRNIRC 223 ++G A+ N S I M + G ++Y+ +K AL T A E+ P IR Sbjct: 161 -RVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRV 219 Query: 224 FTISPGLVKGTDMIQNLP 241 + PGL + ++ ++P Sbjct: 220 NGVGPGL---SVLVDDMP 234 >2QHX-A nrPDB Length = 328 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 58/258 (22%), Positives = 105/258 (40%), Gaps = 49/258 (18%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQR-QCA 62 +PVA+VTGA + +G++I + L +G + + R+A + L + L+ +R A Sbjct: 46 VPVALVTGAAKRLGRSIAEGLHAEGYAVCL------HYHRSAAEANALSATLNARRPNSA 99 Query: 63 IAI-----DFKKWPHWLDYESYDG---IEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYV 114 I + + P DG + F L T + C+ NN +Y Sbjct: 100 ITVQADLSNVATAP----VSGADGSAPVTLFTRCAELVAACYTHWGRCDVLVNNASSFYP 155 Query: 115 NLLIN--------CAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRW 166 L+ C G +E++ T D+ N ++P +++K+ Sbjct: 156 TPLLRNDEDGHEPCVG-DREAMETATA-----DLFGSNAIAPY--------FLIKAFAH- 200 Query: 167 PELSGQSARPTIVNISSILHSGKMK---VPGTSVYSASKAALSRFTEVLAAEMEPRNIRC 223 ++G A+ N S I M + G ++Y+ +K AL T A E+ P IR Sbjct: 201 -RVAGTPAKHRGTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRV 259 Query: 224 FTISPGLVKGTDMIQNLP 241 + PGL + ++ ++P Sbjct: 260 NGVGPGL---SVLVDDMP 274 >3A28-C nrPDB Length = 258 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 53/248 (21%), Positives = 95/248 (38%), Gaps = 43/248 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTG +GIG+ I +KL G + ++ E A + +L Q+ + + Sbjct: 4 VAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQ--EEQAAETIKLIEAAD-QKAVFVGL 60 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D K + + D E+ ++L+N AG+ Q Sbjct: 61 DVTD----------------------KANFDSAIDEAA-----EKLGGFDVLVNNAGIAQ 93 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + T ++ I +VN S + + R++ EL G + + + Sbjct: 94 IKPLLEVTEEDLKQIYSVNVFS-------VFFGIQAASRKFDEL-GVKGKIINAASIAAI 145 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 P S YS +K A+ T+ A E+ P+ +PG+V GT M + + E Sbjct: 146 QG----FPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAYAPGIV-GTGMWEQIDAELS 200 Query: 246 EMLERTIG 253 ++ + IG Sbjct: 201 KINGKPIG 208 >1GEG-A nrPDB Length = 256 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 53/229 (23%), Positives = 88/229 (38%), Gaps = 48/229 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA +GIGKAI +L + G + I + + A + Q A+ + Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGG-----HAVAVKV 58 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTL--FDPCNKWSNNERRYYVNLLINCAGL 123 D D + F ++Q TL FD +++N AG+ Sbjct: 59 DVS-----------DRDQVFA---AVEQARKTLGGFD---------------VIVNNAGV 89 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + T + + N+N + ++ K G + I+N S Sbjct: 90 APSTPIESITPEIVDKVYNINVKGVIWGIQAAVEAFKKE--------GHGGK--IINACS 139 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 +G + P +VYS+SK A+ T+ A ++ P I PG+VK Sbjct: 140 --QAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYCPGIVK 186 >4IIV-A nrPDB Length = 267 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 56/241 (23%), Positives = 92/241 (38%), Gaps = 64/241 (26%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCII-----LGSTKESIERTAIDRGQ---LQSGLSYQR 59 +VTGA++GIG+AI ++L G + + +E++ + G L ++ + Sbjct: 30 LVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSFDVANRE 89 Query: 60 QCAIAIDFKKWPH--WLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLL 117 QC ++ + H W S GI P L + W Sbjct: 90 QCREVLEHEIAQHGAWYGVVSNAGIARDAAFPALSN---------DDW------------ 128 Query: 118 INCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPT 177 +++ N S + CI M+ ++ Q R Sbjct: 129 --------------------DAVIHTNLDSFYNVIQPCIMPMIGAR--------QGGR-- 158 Query: 178 IVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMI 237 I+ +SS+ SG M G YSA+KA + T+ LA E+ R I I+PGL+ T MI Sbjct: 159 IITLSSV--SGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCIAPGLID-TGMI 215 Query: 238 Q 238 + Sbjct: 216 E 216 >1P33-A nrPDB Length = 289 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 63/261 (24%), Positives = 104/261 (39%), Gaps = 35/261 (13%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQR-QCAI 63 PVA+VTGA + +G +I + L +G + + R+A D L + L+ +R AI Sbjct: 8 PVALVTGAAKRLGSSIAEALHAEGYTVCL------HYHRSAADASTLAATLNARRPNSAI 61 Query: 64 AI--DFKKWPHWLDYESYDG---IEYFKDRPPLKQKYSTLFDPCNKWSNNERRYY-VNLL 117 + D + DG + F L + C+ NN +Y LL Sbjct: 62 TVQADLSNVA-TASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLL 120 Query: 118 INCAGL------TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSG 171 AG +ESL V D+ N ++P + + + E G Sbjct: 121 RKDAGEGGSSVGDKESLEVAAA-----DLFGSNAIAPYFLIK---AFAQRVADTRAEQRG 172 Query: 172 QSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 S +IVN+ + S + G ++Y+ +K AL T A E+ IR +SPGL Sbjct: 173 TSY--SIVNMVDAMTSQPLL--GYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL- 227 Query: 232 KGTDMIQNLPVEAKEMLERTI 252 + + ++P +E R + Sbjct: 228 --SVLPDDMPFSVQEDYRRKV 246 >2AG5-A nrPDB Length = 246 Score = 40.8 bits (94), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 37/129 (28%), Positives = 60/129 (46%), Gaps = 14/129 (10%) Query: 103 NKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKS 162 ++++N R +++L N AG + MN+N S M IK + Sbjct: 66 DQFANEVER--LDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSMYLM----IKAFL-- 117 Query: 163 QRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIR 222 P++ Q + I+N+SS+ S K V VYS +KAA+ T+ +AA+ + IR Sbjct: 118 ----PKMLAQKS-GNIINMSSVASSVK-GVVNRCVYSTTKAAVIGLTKSVAADFIQQGIR 171 Query: 223 CFTISPGLV 231 C + PG V Sbjct: 172 CNCVCPGTV 180 >1YXM-A nrPDB Length = 303 Score = 40.4 bits (93), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 63/277 (22%), Positives = 100/277 (36%), Gaps = 52/277 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC-AIA 64 VAIVTG GIGKAI ++L + G S +++ S K ++A D +LQ+ L +Q I Sbjct: 20 VAIVTGGATGIGKAIVKELLELG-SNVVIASRKLERLKSAAD--ELQANLPPTKQARVIP 76 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 I ++ + + D K +N L+N G Sbjct: 77 IQCN----------------IRNEEEVNNLVKSTLDTFGK---------INFLVNNGGGQ 111 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSAR---PTIVNI 181 S + ++ ++ N M MK E G PT Sbjct: 112 FLSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMK------EHGGSIVNIIVPTKAGF 165 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 +HSG A++A + T+ LA E IR ++PG++ ++N Sbjct: 166 PLAVHSG-----------AARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYG 214 Query: 242 VEAKEMLE---RTIGASGTSAPAEIAEEVWSLYSRTA 275 + E + I A P E++ V L S A Sbjct: 215 SWGQSFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 >3KZV-A nrPDB Length = 254 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 56/236 (23%), Positives = 95/236 (40%), Gaps = 51/236 (21%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V +VTG +RGIGK+I LF ++ G + R+ +L+ Sbjct: 4 VILVTGVSRGIGKSIVDVLFSLDKDTVVYG-----VARSEAPLKKLK------------- 45 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 +K+ Y D + LKQ + K ++ L+ AG+ + Sbjct: 46 --EKYGDRFFYVVGD----ITEDSVLKQLVNAAVKGHGK---------IDSLVANAGVLE 90 Query: 126 ESLSVR-TTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +V + + + ++NF S V++ I + PEL + +V +SS Sbjct: 91 PVQNVNEIDVNAWKKLYDINFFSIVSLVGIAL----------PEL--KKTNGNVVFVSS- 137 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 + M Y +SKAAL+ F LA E R ++ ++PG+V TDM N+ Sbjct: 138 -DACNMYFSSWGAYGSSKAALNHFAMTLAN--EERQVKAIAVAPGIVD-TDMQVNI 189 >1MG5-A nrPDB Length = 255 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 33/121 (27%), Positives = 54/121 (44%), Gaps = 18/121 (14%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 V++LIN AG+ + QI+ + VN+ V T + + W + G Sbjct: 86 VDVLINGAGILDDH--------QIERTIAVNYTGLVNTTTAILDF-------WDKRKGGP 130 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 I NI S+ +G + VYS +KAA+ FT LA + +T++PG+ + Sbjct: 131 GG-IICNIGSV--TGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNPGITRT 187 Query: 234 T 234 T Sbjct: 188 T 188 >5YSS-A nrPDB Length = 256 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 55/230 (23%), Positives = 84/230 (36%), Gaps = 57/230 (24%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILG-----STKESIERTAIDRGQLQSGLSYQRQC 61 A+VTG+T GIG I Q L Q G + I+ G + K+++ + G + LS + Q Sbjct: 8 ALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYHGADLSDEAQI 67 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 A D Y E+ V++LIN A Sbjct: 68 A------------DMMRYAESEFGG---------------------------VDILINNA 88 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 G+ S + I+ +N S T + + M R W I+NI Sbjct: 89 GIQHVSPIETFPVDKWNAIIAINLSSVFHTTRLALPGMRA--RNWGR---------IINI 137 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 +S+ G + S Y A+K + T+ +A E I C + PG V Sbjct: 138 ASV--HGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNALCPGWV 185 >2Q2Q-A nrPDB Length = 255 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 50/226 (22%), Positives = 86/226 (38%), Gaps = 49/226 (21%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG+T GIG I Q L + G + ++ G + I R +++ Sbjct: 7 ALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKA------------- 53 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYY-VNLLINCAGLTQ 125 + + D + Q LF + ER + V++L+N AG+ Sbjct: 54 ---------------VHHPADLSDVAQ-IEALF------ALAEREFGGVDILVNNAGIQH 91 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + I+ +N + T + + M R W I+NI+S+ Sbjct: 92 VAPVEQFPLESWDKIIALNLSAVFHGTRLALPGMRA--RNWGR---------IINIASV- 139 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 G + G + Y A+K + T+V+ E N+ C I PG V Sbjct: 140 -HGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICPGWV 184 >4RZI-B nrPDB Length = 240 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 44/161 (27%), Positives = 73/161 (45%), Gaps = 18/161 (11%) Query: 117 LINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARP 176 ++ AG+T+++ + T + ++NVN + Y +K P + G R Sbjct: 79 VVANAGITKDNFFPKLTPADWDAVLNVNLKG--------VAYSIK-----PFIEGMYERK 125 Query: 177 --TIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT 234 +IV ISSI SG+ G + YSA+KA + + LA E +R ++PG + T Sbjct: 126 AGSIVAISSI--SGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFID-T 182 Query: 235 DMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +M + + +E + + I P EIA V L S A Sbjct: 183 EMTLAIREDIREKITKEIPFRRFGKPEEIAWAVAFLLSPVA 223 >4FC7-A nrPDB Length = 277 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 50/236 (21%), Positives = 94/236 (39%), Gaps = 46/236 (19%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA +TG GIG I + + G +I S+ R L+ R+ A A Sbjct: 29 VAFITGGGSGIGFRIAEIFMRHGCHTVI---ASRSLPRV----------LTAARKLAGAT 75 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + P +D + + D+ LK+ +++LINCA Sbjct: 76 GRRCLPLSMDVRAPPAVMAAVDQA-LKEFGR-----------------IDILINCAAGNF 117 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + + + +M+++ ++ + + + IVNI++ L Sbjct: 118 LCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDHGG-----------VIVNITATL 166 Query: 186 HSGKMKVPGTSVYSAS-KAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 + + V++ S KAA+ T LA E P+NIR +++PG + GT+ ++ L Sbjct: 167 GNRGQAL---QVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRL 219 >3WYE-A nrPDB Length = 256 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 54/250 (21%), Positives = 90/250 (36%), Gaps = 49/250 (19%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA +GIGKAI +L + G + I + + A + Q A+ + Sbjct: 4 VALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGG-----HAVAVKV 58 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTL--FDPCNKWSNNERRYYVNLLINCAGL 123 D ++Q TL FD +++N AG+ Sbjct: 59 DVSDRDQVF--------------AAVEQARKTLGGFD---------------VIVNNAGI 89 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 Q + T ++ I +VN S ++ K G + + Sbjct: 90 AQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAAVEAFKKE--------GHGGKIINAASIA 141 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 + P S YS +K A+ T+ A ++ P I PG+V GT M + + E Sbjct: 142 AIQG----FPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYCPGIV-GTGMWEQIDAE 196 Query: 244 AKEMLERTIG 253 ++ + IG Sbjct: 197 LSKINGKPIG 206 >3AUT-A nrPDB Length = 269 Score = 38.9 bits (89), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/136 (23%), Positives = 59/136 (43%), Gaps = 19/136 (13%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 ++++IN AG+ S + +++ N + IKY +++ Sbjct: 94 LDVMINNAGVENPVPSHELSLDNWNKVIDTNLTGAFLGSREAIKYFVEND---------- 143 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 + ++N+SS+ H + P Y+ASK + TE LA E P+ IR I PG + Sbjct: 144 IKGNVINMSSV-HE-MIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAM-- 199 Query: 234 TDMIQNLPVEAKEMLE 249 N P+ A++ + Sbjct: 200 -----NTPINAEKFAD 210 >1OAA-A nrPDB Length = 259 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 58/227 (25%), Positives = 98/227 (43%), Gaps = 39/227 (17%) Query: 6 VAIVTGATRGIGKAIC---QKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 V ++TGA+RG G+A+ +L G S +++ + ES+ R QL+ L Q+ Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPG-SVMLVSARSESMLR------QLKEELGAQQP-- 58 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 D K D + G+ Q+ + + +R +N Sbjct: 59 ---DLKVVLAAADLGTEAGV----------QRLLSAVRELPRPEGLQRLLLINNAATLGD 105 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 +++ L+V A ++ + +N S + +T+ + S P LS T+VNIS Sbjct: 106 VSKGFLNVNDLA-EVNNYWALNLTSMLCLTSGTLNAFQDS----PGLS-----KTVVNIS 155 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 S+ K G +Y A KAA +VLAAE EP ++R + +PG Sbjct: 156 SLCALQPYK--GWGLYCAGKAARDMLYQVLAAE-EP-SVRVLSYAPG 198 >4E6P-A nrPDB Length = 259 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 46/227 (20%), Positives = 83/227 (36%), Gaps = 47/227 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TG+ RGIG+A + ++G + I IER RQ A I Sbjct: 11 ALITGSARGIGRAFAEAYVREGATVAI---ADIDIERA--------------RQAAAEIG 53 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + +D D I+ + E +++L+N A L Sbjct: 54 PAAYAVQMDVTRQDSID------------------AAIAATVEHAGGLDILVNNAALFDL 95 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + V T + + +N + + M+ R I+N++S Sbjct: 96 APIVEITRESYEKLFAINVAGTLFTLQAAARQMIAQGRGGK----------IINMAS--Q 143 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 +G+ ++Y A+KAA+ T+ ++ I I+PG+V G Sbjct: 144 AGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAIAPGVVDG 190 >3E9N-A nrPDB Length = 245 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 31/128 (24%), Positives = 61/128 (47%), Gaps = 15/128 (11%) Query: 113 YVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 +V+ L++ A + +++ + ++ +++N + P + S++ P L + Sbjct: 75 HVDTLVHAAAVARDTTIEAGSVAEWHAHLDLNVIVPAEL----------SRQLLPAL--R 122 Query: 173 SARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 +A ++ I+S +G PG ++Y+ASK AL + E IR T+SPG Sbjct: 123 AASGCVIYINS--GAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGPTN 180 Query: 233 GTDMIQNL 240 T M+Q L Sbjct: 181 -TPMLQGL 187 >5ILO-A nrPDB Length = 271 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 52/236 (22%), Positives = 94/236 (39%), Gaps = 52/236 (22%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG GIG + ++L G + + + ++++E R ++ Q + I Sbjct: 18 AVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRA------AHPTQSVMIIK 71 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 +D + G+E +T + + N +++++N AG+ + Sbjct: 72 -------MDVANKKGVE------------ATYEEIAKTFGN------IDIVVNVAGIFND 106 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 +Q + VN + T + YM K G+ +VN+SS++ Sbjct: 107 K--------DVQRTLLVNLGGIINSTLSALPYMGKDN------GGKGG--IVVNMSSVVG 150 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAE--MEPRNIRCFTISPGLVKGTDMIQNL 240 M + VY A+KA + FT LA E + I+ T+ PG TDM N Sbjct: 151 LDPMFI--IPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATM-TDMFTNF 203 >2FWM-X nrPDB Length = 250 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 37/142 (26%), Positives = 58/142 (40%), Gaps = 16/142 (11%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 ++ L+N AG+ + + + + Q VN + + M RR Q Sbjct: 75 LDALVNAAGILRMGATDQLSKEDWQQTFAVNVGGAFNL----FQQTMNQFRR------QR 124 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 + S H+ ++ G S Y ASKAAL + E+ +RC +SPG Sbjct: 125 GGAIVTVASDAAHTPRI---GMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD- 180 Query: 234 TDMIQNLPV--EAKEMLERTIG 253 TDM + L V +A+E R G Sbjct: 181 TDMQRTLWVSDDAEEQRIRGFG 202 >5TF4-A nrPDB Length = 274 Score = 38.1 bits (87), Expect = 0.004, Method: Compositional matrix adjust. Identities = 36/121 (29%), Positives = 59/121 (48%), Gaps = 15/121 (12%) Query: 114 VNLLINCAGLT-QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 ++ L++ G + +E LS R DI NFM +TM NI + + +R +L Sbjct: 91 LDFLVHAIGFSDKEELSGRYV-----DISESNFM--MTM-NISVYSLTALTKRAEKLMSD 142 Query: 173 SARPTIVNISSILHSGKMKV-PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 +I ++ + G KV P +V +KAAL + LA ++ P++IR IS G + Sbjct: 143 GG-----SILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAISAGPI 197 Query: 232 K 232 K Sbjct: 198 K 198 >1DOH-A nrPDB Length = 283 Score = 37.7 bits (86), Expect = 0.005, Method: Compositional matrix adjust. Identities = 51/233 (21%), Positives = 89/233 (38%), Gaps = 50/233 (21%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCII--LGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 VA+VTGA RGIG+ + +L ++G I+ ST+ + E A + + + Sbjct: 31 VALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGSDAACVKANVGV 90 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 D + +F+ K + L I C Sbjct: 91 VEDIVR----------------------------MFEEAVK-------IFGKLDIVC--- 112 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 S S + ++D+ F T+ ++ + + E+ G+ ++ + S Sbjct: 113 ---SNSGVVSFGHVKDVTPEEFDRVFTINTRGQFFVAREAYKHLEIGGR-----LILMGS 164 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 I K VP +VYS SK A+ F +A +M + I ++PG +K TDM Sbjct: 165 ITGQAK-AVPKHAVYSGSKGAIETFARCMAIDMADKKITVNVVAPGGIK-TDM 215 >3RWB-A nrPDB Length = 247 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 27/84 (32%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 193 PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP-VEAKEMLERT 251 P + Y A+K + FT LA E+ NI ++PGL++ +D ++ P EA +E Sbjct: 148 PNMAAYVAAKGGVIGFTRALATELGKYNITANAVTPGLIE-SDGVKASPHNEAFGFVEML 206 Query: 252 IGASGTSAPAEIAEEVWSLYSRTA 275 G P IA+ V L S A Sbjct: 207 QAMKGKGQPEHIADVVSFLASDDA 230 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 14/27 (51%), Positives = 19/27 (70%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCII 33 A+VTGA +GIGKAI +L G + I+ Sbjct: 9 ALVTGAAQGIGKAIAARLAADGATVIV 35 >5ITV-A nrPDB Length = 255 Score = 37.7 bits (86), Expect = 0.006, Method: Compositional matrix adjust. Identities = 31/140 (22%), Positives = 58/140 (41%), Gaps = 20/140 (14%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 +++LIN AG+ + S ++ VN M+ +K+M+ + Sbjct: 83 LDVLINNAGIEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALKHMLAA----------- 131 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 + I+N S+ G + P Y+ASK + + T+ +A + IR + PG++ Sbjct: 132 GKGNIINTCSV--GGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGII-- 187 Query: 234 TDMIQNLPVEAKEMLERTIG 253 + P+ K LE G Sbjct: 188 -----DTPLNEKSFLENNEG 202 >4Z3K-A nrPDB Length = 275 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 17/126 (13%) Query: 116 LLINCAGL---TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 LLIN AG + + ++Q+ + +N S + +T+ +K +P+ G Sbjct: 110 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKA-------FPDSPGL 162 Query: 173 SARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 + T+VNISS+ K G ++Y A KAA +VLA E EP N+R +PG + Sbjct: 163 NR--TVVNISSLCALQPFK--GWALYCAGKAARDMLFQVLALE-EP-NVRVLNYAPGPLD 216 Query: 233 GTDMIQ 238 TDM Q Sbjct: 217 -TDMQQ 221 >4HWK-A nrPDB Length = 288 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 40/126 (31%), Positives = 62/126 (49%), Gaps = 17/126 (13%) Query: 116 LLINCAGL---TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 LLIN AG + + ++Q+ + +N S + +T+ +K +P+ G Sbjct: 123 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKA-------FPDSPGL 175 Query: 173 SARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 + T+VNISS+ K G ++Y A KAA +VLA E EP N+R +PG + Sbjct: 176 NR--TVVNISSLCALQPFK--GWALYCAGKAARDMLFQVLALE-EP-NVRVLNYAPGPLD 229 Query: 233 GTDMIQ 238 TDM Q Sbjct: 230 -TDMQQ 234 >3W8F-A nrPDB Length = 260 Score = 37.4 bits (85), Expect = 0.007, Method: Compositional matrix adjust. Identities = 56/227 (24%), Positives = 89/227 (39%), Gaps = 45/227 (19%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTK-ESIERTAIDRGQLQSGLSYQRQCAIAI 65 A+VTG+T GIG A+ +L + G +I G + E IER +R L Sbjct: 7 AVVTGSTSGIGLAMATELAKAGADVVINGFGQPEDIER---ERSTL-------------- 49 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 ES G++ + L +T D K + E +++L+N AG+ Sbjct: 50 -----------ESKFGVKAYYLNADLSDAQATR-DFIAKAA--EALGGLDILVNNAGIQH 95 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + I+ +N + T + M K + W I+NI+S Sbjct: 96 TAPIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQK--QGWGR---------IINIAS-- 142 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 G + S Y A+K + T+V A E + I C I PG V+ Sbjct: 143 AHGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCNAICPGWVR 189 >3UF0-A nrPDB Length = 273 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 49/229 (21%), Positives = 88/229 (38%), Gaps = 55/229 (24%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGST---KESIERTAIDRGQLQSGLSYQRQCAI 63 A+VTGA GIG+AI + G + G T KE + A G ++ ++ Sbjct: 34 AVVTGAGSGIGRAIAHGYARAGAHVLAWGRTDGVKEVADEIADGGGSAEAVVA------- 86 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 D +G + ++ V++L+N AG+ Sbjct: 87 -----------DLADLEGAANVAEELAATRR-------------------VDVLVNNAGI 116 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + + + + ++++ VN + ++ M+ SG+ IV I+S Sbjct: 117 IARAPAEEVSLGRWREVLTVNLDAAWVLSRSFGTAMLAHG------SGR-----IVTIAS 165 Query: 184 ILH-SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 +L G V + Y+ASK A+ T LA+E R + ++PG V Sbjct: 166 MLSFQGGRNV---AAYAASKHAVVGLTRALASEWAGRGVGVNALAPGYV 211 >5L51-A nrPDB Length = 324 Score = 37.0 bits (84), Expect = 0.010, Method: Compositional matrix adjust. Identities = 68/300 (22%), Positives = 104/300 (34%), Gaps = 106/300 (35%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTK----ESIERTAIDRGQLQSGLSYQRQCA 62 A+VTGA +GIG IC++L KG++ I+ + E+ ER + G +Q Sbjct: 18 AVVTGANKGIGFEICKQLASKGITVILASRDEKRGIEARERLIKELGSEFGDYVVSQQLD 77 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 +A D +D+ +K K+ +L ++L+N AG Sbjct: 78 VA-DPASVAALVDF--------------IKTKFGSL----------------DILVNNAG 106 Query: 123 LTQESLSVRTTASQIQDIMNVNF---------------------MSPVTMTNICIKYMMK 161 L + AS + D + F + V CI+ Sbjct: 107 LN--GTYMEGDASVLNDYVEAEFKTFQSGAAKTEPYHPKATGRLVETVEHAKECIETNYY 164 Query: 162 SQRRWPE----LSGQSARPTIVNISSILHS------------------------------ 187 +R E L QS P IVN+SS L S Sbjct: 165 GSKRVTEALIPLLQQSDSPRIVNVSSTLSSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAE 224 Query: 188 -------GKMKV----PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 GK + P S Y SKAAL+ +T ++A + + R + PG K TD+ Sbjct: 225 FLKDFIDGKQQEKQWPPHFSAYKVSKAALNAYTRIIAKKYP--SFRINAVCPGYTK-TDL 281 >3DWF-A nrPDB Length = 276 Score = 36.6 bits (83), Expect = 0.012, Method: Compositional matrix adjust. Identities = 47/209 (22%), Positives = 83/209 (39%), Gaps = 45/209 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 IVTGA++GIG+ I L + G ++ +KE++++ L+ G + A +++ Sbjct: 15 IVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVAR--CLELGAASAHYIAGSMED 72 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 + E+ + L L N N ++ + N Sbjct: 73 MTFAE----------EFVAEAGNLMGGLDMLI--LNHVLYNRLTFFHGEIDN-------- 112 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 ++ M VNF S V ++ + +M+SQ +I +SS+ + Sbjct: 113 ---------VRKSMEVNFHSFVVLSVAAMPMLMQSQ------------GSIAVVSSV--A 149 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEM 216 GK+ P + YSASK AL F L +E Sbjct: 150 GKITYPLIAPYSASKFALDGFFSTLRSEF 178 >3V8B-A nrPDB Length = 283 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 24/41 (58%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTA 45 PVA++TGA GIG+A L G++ LG T+ +E A Sbjct: 29 PVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVA 69 >2HSD-A nrPDB Length = 253 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 40/162 (24%), Positives = 69/162 (42%), Gaps = 14/162 (8%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 V+ L+N AG++ + + + ++ +N T I +K ++ + + + Sbjct: 80 VDGLVNNAGISTGMFLETESVERFRKVVEINL----TGVFIGMKTVIPAMK-------DA 128 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 +IVNISS +G M + TS Y ASK + +++ A E+ IR ++ PG+ Sbjct: 129 GGGSIVNISS--AAGLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTY- 185 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 T M + E P EIA V L S T+ Sbjct: 186 TPMTAETGIRQGEGNYPNTPMGRVGEPGEIAGAVVKLLSDTS 227 >2HRB-A nrPDB Length = 274 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 46/180 (25%), Positives = 72/180 (40%), Gaps = 46/180 (25%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQS-GLSYQRQCAIA 64 VA+VTGA RGIG AI ++L ++ ++L T + R QLQ+ GLS + Sbjct: 4 VALVTGANRGIGLAIARELCRQFSGDVVL--TARDVARGQAAVQQLQAEGLSPRF----- 56 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 H LD + I +D L+++Y L N+L+N A + Sbjct: 57 -------HQLDIDDLQSIRALRDF--LRKEYGGL----------------NVLVNNAAVA 91 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +S + + + NF + M N + M R +VNISS+ Sbjct: 92 FKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKPHGR-------------VVNISSL 138 >5PGZ-A nrPDB Length = 276 Score = 36.2 bits (82), Expect = 0.017, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 46/95 (48%), Gaps = 15/95 (15%) Query: 123 LTQESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 +TQ SLS+ ++ +M VNF+S V M+ + + +S +I I Sbjct: 105 ITQTSLSLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQSN------------GSIAVI 152 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEM 216 SS+ +GKM P + YSASK AL F + E+ Sbjct: 153 SSL--AGKMTQPMIAPYSASKFALDGFFSTIRTEL 185 Score = 28.9 bits (63), Expect = 2.4, Method: Compositional matrix adjust. Identities = 11/37 (29%), Positives = 23/37 (62%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERT 44 IVTGA++GIG+ + L + G ++ ++E +++ Sbjct: 22 IVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKV 58 >3T7C-A nrPDB Length = 299 Score = 36.2 bits (82), Expect = 0.018, Method: Compositional matrix adjust. Identities = 53/237 (22%), Positives = 89/237 (37%), Gaps = 34/237 (14%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA +TGA RG G++ L ++G I + K+ ++ + RQ A+ Sbjct: 30 VAFITGAARGQGRSHAITLAREGADIIAIDVCKQ-LDGVKLPMSTPDDLAETVRQVE-AL 87 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + +D +D ++ D D + +++++ A L Sbjct: 88 GRRIIASQVDVRDFDAMQAAVD------------DGVTQLGR------LDIVLANAALAS 129 Query: 126 ESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 E + R +D+++VN + I ++M +R +IV SSI Sbjct: 130 EGTRLNRMDPKTWRDMIDVNLNGAWITARVAIPHIMAGKRGG----------SIVFTSSI 179 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 G Y ASK L +A E+ PRNIR + P V T M+ N P Sbjct: 180 --GGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVA-TPMLLNEP 233 >4AVY-A nrPDB Length = 242 Score = 35.8 bits (81), Expect = 0.022, Method: Compositional matrix adjust. Identities = 48/223 (21%), Positives = 86/223 (38%), Gaps = 60/223 (26%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG + GIG AI + + G + LG + + Sbjct: 15 LVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHA------------------------ 50 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 + P + E D + Q+ LF+ + +++L+N AG++++ Sbjct: 51 PRHPR-IRREELDITD--------SQRLQRLFEALPR---------LDVLVNNAGISRDR 92 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 + + ++ +N + M+ SQ P L+ + +I+NI+S+ + Sbjct: 93 EEYDL--ATFERVLRLNLSAA----------MLASQLARPLLAQRGG--SILNIASMYST 138 Query: 188 -GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 G P YSASK A+ + T LA E IR I+PG Sbjct: 139 FGSADRP---AYSASKGAIVQLTRSLACEYAAERIRVNAIAPG 178 >1H5Q-A nrPDB Length = 265 Score = 35.8 bits (81), Expect = 0.023, Method: Compositional matrix adjust. Identities = 40/159 (25%), Positives = 66/159 (41%), Gaps = 6/159 (3%) Query: 117 LINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARP 176 LI AG++ + T + +VN K ++ Q++ + S Sbjct: 96 LIANAGVSVVKPATELTHEDFAFVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSS 155 Query: 177 TIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 I+N SS L+ +V Y++SKAA S + LAAE IR +SPG V TD Sbjct: 156 QIINQSS-LNGSLTQV----FYNSSKAACSNLVKGLAAEWASAGIRVNALSPGYVN-TDQ 209 Query: 237 IQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 ++ + ++ I + + P E+ + L S A Sbjct: 210 TAHMDKKIRDHQASNIPLNRFAQPEEMTGQAILLLSDHA 248 >4TRR-A nrPDB Length = 269 Score = 35.0 bits (79), Expect = 0.036, Method: Compositional matrix adjust. Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 12/96 (12%) Query: 152 TNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEV 211 T +K+M K R ++ + S+ HS + P S Y +K L V Sbjct: 130 TKAALKHMYKDDRGG----------VVIYMGSV-HSHEAS-PLKSAYVTAKHGLLGLARV 177 Query: 212 LAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 LA E N+R + PG V+ + + +P +AKE+ Sbjct: 178 LAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKEL 213 >3GRK-A nrPDB Length = 293 Score = 35.0 bits (79), Expect = 0.036, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 56/121 (46%), Gaps = 15/121 (12%) Query: 114 VNLLINCAGLT-QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQ 172 ++ L++ G + ++ L+ R + + N +S ++T + RR +L Sbjct: 110 LDFLVHAIGFSDKDELTGRYIDTSEANFTNTMLISVYSLTAVS--------RRAEKLMAD 161 Query: 173 SARPTIVNISSILHSGKMKV-PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 +I ++ + G KV P +V +KAAL + LA ++ P+NIR IS G + Sbjct: 162 GG-----SILTLTYYGAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIRVNAISAGPI 216 Query: 232 K 232 K Sbjct: 217 K 217 >3OIG-A nrPDB Length = 266 Score = 35.0 bits (79), Expect = 0.037, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 53/112 (47%), Gaps = 17/112 (15%) Query: 172 QSARPTIVNISSILH----SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTIS 227 ++ARP + SI+ G++ +P +V +KA+L + LAA++ NIR +IS Sbjct: 131 KAARPMMTEGGSIVTLTYLGGELVMPNYNVMGVAKASLDASVKYLAADLGKENIRVNSIS 190 Query: 228 PGLV-----KGTDMIQNL--PVEAKEMLERTIGASGTSAPAEIAEEVWSLYS 272 G + KG ++ +E + L R T+ P E+ + L+S Sbjct: 191 AGPIRTLSAKGISDFNSILKDIEERAPLRR------TTTPEEVGDTAAFLFS 236 >3V2H-A nrPDB Length = 281 Score = 35.0 bits (79), Expect = 0.038, Method: Compositional matrix adjust. Identities = 58/239 (24%), Positives = 88/239 (36%), Gaps = 43/239 (17%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TG+T GIG AI + L + G + ++ G RT D +GLS D Sbjct: 28 AVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDE---VAGLSSGTVLHHPAD 84 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 K E D + DR F + NN +V + E Sbjct: 85 MTK-----PSEIADMMAMVADR----------FGGADILVNNAGVQFVEKI--------E 121 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 V Q I+ VN S I M K + W I+NI+S Sbjct: 122 DFPVE----QWDRIIAVNLSSSFHTIRGAIPPMKK--KGWGR---------IINIAS--A 164 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G + P S Y A+K + T+ +A E+ + +I PG V + + +P +A+ Sbjct: 165 HGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSICPGYVLTPLVEKQIPDQAR 223 >5T5Q-A nrPDB Length = 247 Score = 35.0 bits (79), Expect = 0.038, Method: Compositional matrix adjust. Identities = 46/225 (20%), Positives = 90/225 (40%), Gaps = 49/225 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++TGA GIG+AI + G + ++ +E ++ A G + + + + A D Sbjct: 13 VLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSADDA 72 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 +K L E + GI++ L+ AG+ Q Sbjct: 73 EKTV-ALAMERFGGIDF--------------------------------LVPSAGIYQ-- 97 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 A ++ + ++ +++ + Y+ K R P L S +IV ++S+ Sbjct: 98 ------AKPFAEMSDADWHRTISINLDGVFYLCK--RALPALKEDS---SIVTLASLAAY 146 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 V + Y A+K A+ T L+ E+ P+ R +SPG+++ Sbjct: 147 RGAYV--NAHYGATKGAMVSMTRALSRELAPKT-RVNGVSPGIIE 188 >5LCX-A nrPDB Length = 316 Score = 33.9 bits (76), Expect = 0.078, Method: Compositional matrix adjust. Identities = 17/33 (51%), Positives = 24/33 (72%), Gaps = 1/33 (3%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKE 39 A+VTGA +GIG IC++L +KG+ +IL S E Sbjct: 10 ALVTGANKGIGFEICRQLAEKGI-IVILTSRNE 41 >3PXX-A nrPDB Length = 287 Score = 33.9 bits (76), Expect = 0.083, Method: Compositional matrix adjust. Identities = 55/246 (22%), Positives = 101/246 (41%), Gaps = 45/246 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERT----AIDRGQLQSGLSYQRQC 61 V +VTG RG G++ KL ++G + IIL IE A R ++GL ++ Sbjct: 12 VVLVTGGARGQGRSHAVKLAEEG-ADIILFDICHDIETNEYPLATSRDLEEAGLEVEKTG 70 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 K + +D +DR + ++ + K +++++ A Sbjct: 71 R-----KAYTAEVD---------VRDRAAVSRELANAVAEFGK---------LDVVVANA 107 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPT---- 177 G+ L D +V+F+ + + + Y+ SG S T Sbjct: 108 GIC--PLGAHLPVQAFADAFDVDFVGVINTVHAALPYLT---------SGASIITTGSVA 156 Query: 178 -IVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 ++ + +G + PG + YS +K + +T LAA++ P++IR I P V TDM Sbjct: 157 GLIAAAQPPGAGGPQGPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVN-TDM 215 Query: 237 IQNLPV 242 + + P+ Sbjct: 216 LNSAPM 221 >1O5I-A nrPDB Length = 249 Score = 33.9 bits (76), Expect = 0.084, Method: Compositional matrix adjust. Identities = 58/270 (21%), Positives = 104/270 (38%), Gaps = 64/270 (23%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +V A+RGIG+A+ L Q+G I +E ++R SG Y + D Sbjct: 23 LVLAASRGIGRAVADVLSQEGAEVTICARNEELLKR---------SGHRY-----VVCD- 67 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 L++ LF E+ V++L+ AG + Sbjct: 68 -----------------------LRKDLDLLF---------EKVKEVDILVLNAGGPKAG 95 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYM--MKSQRRWPELSGQSARPTIVNISSIL 185 T ++ ++ F++ M I Y+ MK ++ W + ++ I I ++ Sbjct: 96 FFDELTNEDFKEAIDSLFLN---MIKIVRNYLPAMK-EKGWGRIVAITSFSVISPIENLY 151 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 S ++++ AL+ F + L+ E+ P I ++PG + + + L E K Sbjct: 152 TS-----------NSARMALTGFLKTLSFEVAPYGITVNCVAPGWTETERVKELLSEEKK 200 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + +E I + P EIA V L S A Sbjct: 201 KQVESQIPMRRMAKPEEIASVVAFLCSEKA 230 >5OVL-A nrPDB Length = 300 Score = 33.5 bits (75), Expect = 0.095, Method: Compositional matrix adjust. Identities = 27/132 (20%), Positives = 60/132 (45%), Gaps = 14/132 (10%) Query: 109 ERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 E + V +L+ AG+++++ +R T + ++++N N + M + +R+ Sbjct: 130 EHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQR--KRFGR 187 Query: 169 LSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 I+ I S+ SG + + Y+A+KA L ++ E+ + ++P Sbjct: 188 ---------IIFIGSV--SGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAP 236 Query: 229 GLVKGTDMIQNL 240 G + T+M + L Sbjct: 237 GYID-TEMTRAL 247 >5OVJ-A nrPDB Length = 256 Score = 33.5 bits (75), Expect = 0.11, Method: Compositional matrix adjust. Identities = 27/132 (20%), Positives = 60/132 (45%), Gaps = 14/132 (10%) Query: 109 ERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 E + V +L+ AG+++++ +R T + ++++N N + M + +R+ Sbjct: 86 EHQGPVEVLVANAGISKDAFLMRMTEERFEEVINTNLTGAFRCAQRASRTMQR--KRFGR 143 Query: 169 LSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 I+ I S+ SG + + Y+A+KA L ++ E+ + ++P Sbjct: 144 ---------IIFIGSV--SGMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAP 192 Query: 229 GLVKGTDMIQNL 240 G + T+M + L Sbjct: 193 GYID-TEMTRAL 203 >4EGF-A nrPDB Length = 266 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 36/147 (24%), Positives = 59/147 (40%), Gaps = 24/147 (16%) Query: 114 VNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 +++L+N AG++ V T + VN +P + + K M+ + G+ Sbjct: 99 LDVLVNNAGISHPQPVVDTDPQLFDATIAVNLRAPALLASAVGKAMVAA--------GEG 150 Query: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 I+ ++S + Y SKA L T+VLA E+ P IR ++ P +V Sbjct: 151 G--AIITVASAAALAPLP--DHYAYCTSKAGLVMATKVLARELGPHGIRANSVCPTVVL- 205 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAP 260 EM +R G SAP Sbjct: 206 -----------TEMGQRVWGDEAKSAP 221 >3OML-A nrPDB Length = 613 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 49/225 (21%), Positives = 80/225 (35%), Gaps = 43/225 (19%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGL-SYQRQCAIA 64 VA+VTGA G+G+ ++G ++ D G SG + QR I Sbjct: 21 VAVVTGAGAGLGREYALLFAERGAKVVV------------NDLGGTHSGDGASQRAADIV 68 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRY-YVNLLINCAGL 123 +D E K Y+++ D + + V++L+N AG+ Sbjct: 69 VD----------------EIRKAGGEAVADYNSVIDGAKVIETAIKAFGRVDILVNNAGI 112 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 ++ V+T+ + +V+ T YM K I+ SS Sbjct: 113 LRDRSLVKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQN-----------YGRIIMTSS 161 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 +SG G Y+A+K L +A E N+ C I P Sbjct: 162 --NSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLCNVIVP 204 >3BHI-A nrPDB Length = 276 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 46/189 (24%), Positives = 75/189 (39%), Gaps = 50/189 (26%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQS-GLSYQRQCAIA 64 VA+VTG +GIG AI + L + ++L T + R QLQ+ GLS + Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVL--TARDVTRGQAAVQQLQAEGLSPRF----- 58 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 H LD + I +D L+++Y L ++L+N AG+ Sbjct: 59 -------HQLDIDDLQSIRALRDF--LRKEYGGL----------------DVLVNNAGIA 93 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKY--MMKSQRRWPELSGQSARPTIVNIS 182 + Q + M NF ++C + ++K Q R +VN+S Sbjct: 94 FKVADPTPFHIQAEVTMKTNFFG---TRDVCTELLPLIKPQGR------------VVNVS 138 Query: 183 SILHSGKMK 191 SI+ +K Sbjct: 139 SIMSVRALK 147 >3UVE-A nrPDB Length = 286 Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust. Identities = 53/251 (21%), Positives = 91/251 (36%), Gaps = 62/251 (24%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCI----------------ILGSTKESIERTAIDRG 49 VA VTGA RG G++ +L Q+G I I ST E + TA Sbjct: 13 VAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETA---- 68 Query: 50 QLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNE 109 L G + R+ A +D YD ++ D S E Sbjct: 69 DLVKG--HNRRIVTA--------EVDVRDYDALKAAVD------------------SGVE 100 Query: 110 RRYYVNLLINCAGLTQESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 + +++++ AG+ ++ +T+ +++++N + +M+ R Sbjct: 101 QLGRLDIIVANAGIGNGGDTLDKTSEEDWTEMIDINLAGVWKTVKAGVPHMIAGGRGG-- 158 Query: 169 LSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 +I+ SS+ G P T Y A+K + E+ IR ++ P Sbjct: 159 --------SIILTSSV--GGLKAYPHTGHYVAAKHGVVGLMRAFGVELGQHMIRVNSVHP 208 Query: 229 GLVKGTDMIQN 239 VK T M+ N Sbjct: 209 THVK-TPMLHN 218 >6CGE-A nrPDB Length = 328 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 41/142 (28%), Positives = 64/142 (45%), Gaps = 22/142 (15%) Query: 114 VNLLINCAGL----TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 V++L+ AGL E+L AS +++VN + V M + M +RR Sbjct: 85 VDVLVCNAGLGLLGPLEALGEDAVAS----VLDVNVVGTVRMLQAFLPDM---KRRG--- 134 Query: 170 SGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 SG+ ++ S+ G M +P VY ASK AL E LA + P + I G Sbjct: 135 SGR-----VLVTGSV--GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECG 187 Query: 230 LVKGTDMIQNLPVEAKEMLERT 251 V T ++ + +E+L+RT Sbjct: 188 PVH-TAFMEKVLGSPEEVLDRT 208 >1A27-A nrPDB Length = 289 Score = 32.3 bits (72), Expect = 0.25, Method: Compositional matrix adjust. Identities = 39/142 (27%), Positives = 61/142 (42%), Gaps = 22/142 (15%) Query: 114 VNLLINCAGL----TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 V++L+ AGL E+L AS +++VN + V M Q P++ Sbjct: 84 VDVLVCNAGLGLLGPLEALGEDAVAS----VLDVNVVGTVRML----------QAFLPDM 129 Query: 170 SGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG 229 + + +V S G M +P VY ASK AL E LA + P + I G Sbjct: 130 KRRGSGRVLVTGSV---GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECG 186 Query: 230 LVKGTDMIQNLPVEAKEMLERT 251 V T ++ + +E+L+RT Sbjct: 187 PVH-TAFMEKVLGSPEEVLDRT 207 >1N5D-A nrPDB Length = 288 Score = 32.0 bits (71), Expect = 0.28, Method: Compositional matrix adjust. Identities = 26/83 (31%), Positives = 41/83 (49%), Gaps = 5/83 (6%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQS-GLSYQRQCAIA 64 VA+VTGA +GIG AI + L ++ ++L T + R QLQ+ GLS + Sbjct: 6 VALVTGANKGIGFAIVRDLCRQFAGDVVL--TARDVARGQAAVKQLQAEGLSPRFHQLDI 63 Query: 65 IDFKKWPHWLDY--ESYDGIEYF 85 ID + D+ + Y G++ Sbjct: 64 IDLQSIRALCDFLRKEYGGLDVL 86 >3U4C-A nrPDB Length = 281 Score = 32.0 bits (71), Expect = 0.33, Method: Compositional matrix adjust. Identities = 51/227 (22%), Positives = 92/227 (40%), Gaps = 47/227 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A V GA++GIGKAI KL + S +I ++IE D L+ + ++ + Sbjct: 26 AFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDI------LAKHPEASVIVL 79 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 D + GI + + C + +++LIN Sbjct: 80 AGDMS---DQHTRAGI------------FQKIESQCGR---------LDVLIN------- 108 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 ++ A D N+ M+ T T + Y + + +R L Q+ I+NI L Sbjct: 109 --NIPGGAPDTFDNCNIEDMT-ATFTQKTVAY-IDAIKRASSLMKQNEFGRIINIVGNL- 163 Query: 187 SGKMKVPGTSVYSAS--KAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 K PG ++++ S AAL ++ ++ ++ P NI ++PG + Sbjct: 164 ---WKEPGANMFTNSMMNAALINASKNISIQLAPHNITVNCLNPGFI 207 >5KOI-A nrPDB Length = 293 Score = 31.6 bits (70), Expect = 0.38, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 29/54 (53%), Gaps = 1/54 (1%) Query: 180 NISSILHSGKMK-VPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 +I ++ + G + +P +V +KAAL LAA+ P+ IR IS G V+ Sbjct: 162 SILTLTYGGSTRTIPNYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVR 215 >3O26-A nrPDB Length = 311 Score = 30.8 bits (68), Expect = 0.60, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 24/41 (58%), Gaps = 4/41 (9%) Query: 7 AIVTGATRGIGKAICQKLFQKG----LSCIILGSTKESIER 43 A+VTG +GIG IC++L G L+C + E++E+ Sbjct: 15 AVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEK 55 Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust. Identities = 15/37 (40%), Positives = 23/37 (62%), Gaps = 2/37 (5%) Query: 196 SVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 + Y+ SKA L+ +T VLA ++ + C + PGLVK Sbjct: 234 AAYTTSKACLNAYTRVLANKIPKFQVNC--VCPGLVK 268 >3OIC-A nrPDB Length = 258 Score = 30.4 bits (67), Expect = 0.78, Method: Compositional matrix adjust. Identities = 12/27 (44%), Positives = 20/27 (74%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCII 33 A+VTG++RG+GKA +L + G + +I Sbjct: 7 ALVTGSSRGVGKAAAIRLAENGYNIVI 33 >2EW8-A nrPDB Length = 249 Score = 30.0 bits (66), Expect = 1.3, Method: Compositional matrix adjust. Identities = 52/227 (22%), Positives = 89/227 (39%), Gaps = 47/227 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A++TG GIG+AI ++ +G + I + + E A R + L+ + C Sbjct: 9 LAVITGGANGIGRAIAERFAVEG-ADIAIADLVPAPEAEAAIRNLGRRVLTVK--C---- 61 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D +E F KQ ST F C+ +L+N AG+ Sbjct: 62 ---------DVSQPGDVEAFG-----KQVIST-FGRCD------------ILVNNAGIYP 94 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 T Q + +N S M + M ++ W I+N++S Sbjct: 95 LIPFDELTFEQWKKTFEINVDSGFLMAKAFVPGMKRNG--WGR---------IINLTSTT 143 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 + +K+ + Y ++KAA FT LA+++ I I+P LV+ Sbjct: 144 Y--WLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAIAPSLVR 188 >3PF7-A nrPDB Length = 481 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 22/41 (53%) Query: 226 ISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEE 266 I+ G KG D+ Q +P E + L R I G + PA + ++ Sbjct: 87 ITFGEHKGQDVWQEVPGEYRSTLRRIIVTQGDTEPASVEQQ 127 >3PPI-A nrPDB Length = 281 Score = 29.3 bits (64), Expect = 1.9, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 30/51 (58%), Gaps = 1/51 (1%) Query: 194 GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 G + Y+A+KA + T A ++ IR TI+PG +K T +++++ EA Sbjct: 183 GQTAYAAAKAGVIGLTIAAARDLSSAGIRVNTIAPGTMK-TPIMESVGEEA 232 >3ZV3-A nrPDB Length = 281 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 11/44 (25%), Positives = 22/44 (50%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRG 49 VA++TG G+G+A+ + +G +L + E + + G Sbjct: 7 VALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHG 50 >1G4W-R nrPDB Length = 383 Score = 28.9 bits (63), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 19/44 (43%) Query: 45 AIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDR 88 AID+ +Q +R + K WP S D +EY DR Sbjct: 254 AIDQYNMQLSCGEKRYTIPVLHVKNWPDHQPLPSTDQLEYLADR 297 >3R3S-A nrPDB Length = 294 Score = 28.5 bits (62), Expect = 3.4, Method: Compositional matrix adjust. Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 15/99 (15%) Query: 133 TASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKV 192 T+ Q Q VN + +T I + K +I+ SSI Sbjct: 149 TSEQFQQTFAVNVFALFWITQEAIPLLPKGA-------------SIITTSSI--QAYQPS 193 Query: 193 PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 P Y+A+KAA+ ++ LA ++ + IR ++PG + Sbjct: 194 PHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPI 232 >3GLF-B nrPDB Length = 395 Score = 28.1 bits (61), Expect = 4.2, Method: Compositional matrix adjust. Identities = 37/160 (23%), Positives = 61/160 (38%), Gaps = 31/160 (19%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSC-----------------IILGSTKESIERTAIDRG 49 A + TRG+GK +L KGL+C I G + IE A R Sbjct: 62 AYLFSGTRGVGKTSIARLLAKGLNCETGITATPCGVCDNCREIEQGRFVDLIEIDAASRT 121 Query: 50 QLQS--GLSYQRQCAIAID-FKKW----PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPC 102 +++ L Q A A FK + H L S++ + + PP K+ Sbjct: 122 KVEDTRDLLDNVQYAPARGRFKVYLIDEVHMLSRHSFNALLKTLEEPPEHVKFLL----- 176 Query: 103 NKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMN 142 + + ++ V +L C ++L V Q++ I+N Sbjct: 177 --ATTDPQKLPVTILSRCLQFHLKALDVEQIRHQLEHILN 214 >4CR6-A nrPDB Length = 271 Score = 28.1 bits (61), Expect = 4.6, Method: Compositional matrix adjust. Identities = 12/28 (42%), Positives = 18/28 (64%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIIL 34 AIVTGA GIG+A + ++G S + + Sbjct: 18 AIVTGAAGGIGRATVEAYLREGASVVAM 45 >1BDB-A nrPDB Length = 277 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 10/43 (23%), Positives = 20/43 (46%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQ 50 ++TG G+G+A+ + +G +L + E + D G Sbjct: 9 LITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGD 51 >4NK4-A nrPDB Length = 301 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 183 SILHSGKMKV-PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK 232 ++ + G M+V P + + +K+AL T+ LA + NIR IS G V+ Sbjct: 177 TLTYGGSMRVVPNYNAMAPAKSALESSTKYLACDYGGMNIRINAISAGPVR 227 >1AHH-A nrPDB Length = 255 Score = 27.3 bits (59), Expect = 7.7, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 26/57 (45%), Gaps = 1/57 (1%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 AI+TGA GIGK I G S ++ ++ +D Q G ++ +C I Sbjct: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHV-VDEIQQLGGQAFACRCDI 69 >1NJG-A nrPDB Length = 250 Score = 26.9 bits (58), Expect = 9.7, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 15/25 (60%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSC 31 A + TRG+GK +L KGL+C Sbjct: 47 AYLFSGTRGVGKTSIARLLAKGLNC 71 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4HBG-A nrPDB 328 1e-90 2PNF-A nrPDB 224 3e-59 3OSU-A nrPDB 220 5e-58 2C07-A nrPDB 218 1e-57 3LYL-A nrPDB 211 3e-55 2HQ1-A nrPDB 211 3e-55 4JRO-A nrPDB 210 4e-55 3RSH-A nrPDB 209 1e-54 3FTP-A nrPDB 208 2e-54 2PH3-A nrPDB 208 3e-54 5CDY-A nrPDB 205 2e-53 2UVD-A nrPDB 205 2e-53 3EMK-A nrPDB 203 5e-53 3EZL-A nrPDB 203 9e-53 3GRP-A nrPDB 202 1e-52 1Q7C-A nrPDB 198 1e-51 4CQL-A nrPDB 198 2e-51 4KMS-A nrPDB 198 3e-51 3F9I-A nrPDB 198 3e-51 3VZS-A nrPDB 197 6e-51 4M8S-A nrPDB 196 1e-50 4BO1-A nrPDB 195 3e-50 3WOH-A nrPDB 194 4e-50 2CDH-G nrPDB 190 5e-49 4NBV-A nrPDB 190 7e-49 4RZH-A nrPDB 190 8e-49 4DMM-A nrPDB 189 9e-49 4K6F-A nrPDB 188 3e-48 1YXM-A nrPDB 185 2e-47 5VT6-A nrPDB 185 2e-47 4NBT-A nrPDB 184 3e-47 2NM0-A nrPDB 184 4e-47 6NRP-A nrPDB 181 2e-46 4CQM-B nrPDB 179 1e-45 4IIN-A nrPDB 176 7e-45 4IS3-A nrPDB 176 1e-44 3O4R-A nrPDB 173 7e-44 2AE2-A nrPDB 169 1e-42 2ZAT-A nrPDB 169 1e-42 1AE1-A nrPDB 168 2e-42 4DBZ-A nrPDB 168 3e-42 4RZI-B nrPDB 167 4e-42 1GEG-A nrPDB 167 4e-42 1UZM-A nrPDB 166 8e-42 4IIV-A nrPDB 166 8e-42 1GEE-A nrPDB 165 3e-41 5B1Y-A nrPDB 163 5e-41 2GDZ-A nrPDB 163 1e-40 3OEC-A nrPDB 162 1e-40 2X9N-A nrPDB 161 3e-40 3WTC-A nrPDB 160 6e-40 3A28-C nrPDB 160 8e-40 3U5T-A nrPDB 160 9e-40 6CI9-A nrPDB 159 1e-39 2CFC-A nrPDB 159 1e-39 1P33-A nrPDB 156 1e-38 5OJG-A nrPDB 155 2e-38 1NFF-A nrPDB 154 5e-38 4MOW-A nrPDB 153 6e-38 2Q2Q-A nrPDB 153 9e-38 2QHX-A nrPDB 153 9e-38 2NWQ-A nrPDB 153 1e-37 2BFA-A nrPDB 152 1e-37 5YSS-A nrPDB 151 2e-37 3V2G-A nrPDB 151 2e-37 4Z9Y-A nrPDB 150 5e-37 4FC7-A nrPDB 150 6e-37 1X1T-A nrPDB 150 8e-37 1CYD-A nrPDB 148 2e-36 3D3W-A nrPDB 148 2e-36 2B4Q-A nrPDB 148 2e-36 4HP8-A nrPDB 147 5e-36 1K2W-A nrPDB 146 1e-35 2O23-A nrPDB 141 3e-34 5IZ4-A nrPDB 141 3e-34 1E3W-A nrPDB 136 7e-33 2AG5-A nrPDB 134 4e-32 4DA9-A nrPDB 122 2e-28 5JS6-A nrPDB 119 9e-28 3RKU-A nrPDB 118 3e-27 1SNY-A nrPDB 109 1e-24 3KZV-A nrPDB 101 3e-22 1B15-A nrPDB 89 2e-18 1MG5-A nrPDB 85 2e-17 Sequences not found previously or not previously below threshold: 5OVL-A nrPDB 171 3e-43 5OVJ-A nrPDB 166 8e-42 5ITV-A nrPDB 162 1e-40 3WYE-A nrPDB 162 1e-40 3AUT-A nrPDB 159 2e-39 3V2H-A nrPDB 153 7e-38 5T5Q-A nrPDB 150 5e-37 3W8F-A nrPDB 148 3e-36 5U9P-A nrPDB 148 4e-36 3RWB-A nrPDB 144 4e-35 2EW8-A nrPDB 139 1e-33 4AVY-A nrPDB 136 7e-33 4E6P-A nrPDB 136 1e-32 3UVE-A nrPDB 135 3e-32 3T7C-A nrPDB 133 8e-32 1H5Q-A nrPDB 133 8e-32 1O5I-A nrPDB 132 1e-31 3OML-A nrPDB 132 2e-31 3UF0-A nrPDB 128 4e-30 1DOH-A nrPDB 128 4e-30 3R3S-A nrPDB 127 4e-30 2FWM-X nrPDB 127 6e-30 2HSD-A nrPDB 126 8e-30 3V8B-A nrPDB 126 1e-29 3OIC-A nrPDB 125 2e-29 1HXH-A nrPDB 125 2e-29 1AHH-A nrPDB 125 3e-29 5EJ2-A nrPDB 124 6e-29 4EGF-A nrPDB 123 9e-29 5O3Z-A nrPDB 122 2e-28 4CR6-A nrPDB 119 1e-27 4TRR-A nrPDB 116 1e-26 3UN1-A nrPDB 114 3e-26 3GDF-A nrPDB 109 9e-25 3ZV3-A nrPDB 109 1e-24 3PPI-A nrPDB 105 2e-23 1W73-A nrPDB 100 8e-22 1BDB-A nrPDB 100 1e-21 3PXX-A nrPDB 99 2e-21 1A27-A nrPDB 98 3e-21 5ILO-A nrPDB 98 4e-21 2BGM-A nrPDB 98 4e-21 3U4C-A nrPDB 97 6e-21 6CGE-A nrPDB 97 7e-21 4DRY-A nrPDB 97 8e-21 3E9N-A nrPDB 96 1e-20 4RGB-A nrPDB 95 4e-20 5JY1-A nrPDB 89 2e-18 3DWF-A nrPDB 86 2e-17 4GKB-A nrPDB 85 5e-17 5PGZ-A nrPDB 84 7e-17 2HRB-A nrPDB 80 1e-15 4Z3K-A nrPDB 79 2e-15 4HWK-A nrPDB 79 2e-15 1N5D-A nrPDB 77 7e-15 3BHI-A nrPDB 76 1e-14 1OAA-A nrPDB 74 6e-14 5L51-A nrPDB 73 1e-13 3O26-A nrPDB 73 1e-13 2P91-A nrPDB 73 2e-13 3U9L-A nrPDB 69 2e-12 2YW9-A nrPDB 68 5e-12 3OIG-A nrPDB 64 5e-11 2DKN-A nrPDB 64 6e-11 2O2S-A nrPDB 61 6e-10 4Q9N-A nrPDB 60 1e-09 5WQO-A nrPDB 59 2e-09 5YCX-A nrPDB 58 6e-09 5TF4-A nrPDB 57 8e-09 5LCX-A nrPDB 56 1e-08 3UCF-A nrPDB 56 2e-08 5TQV-A nrPDB 55 3e-08 4ALL-A nrPDB 55 3e-08 4ZJU-A nrPDB 55 3e-08 1ENP-A nrPDB 54 5e-08 5CFZ-A nrPDB 54 6e-08 1FJH-A nrPDB 54 7e-08 5KOI-A nrPDB 54 7e-08 3GRK-A nrPDB 54 7e-08 4JQC-A nrPDB 53 1e-07 4NR0-A nrPDB 52 2e-07 4M89-A nrPDB 51 5e-07 4NK4-A nrPDB 50 9e-07 2PTG-A nrPDB 50 1e-06 5I9N-A nrPDB 49 2e-06 4J3F-A nrPDB 46 1e-05 3F4B-A nrPDB 45 3e-05 3SLK-A nrPDB 44 5e-05 3K2E-A nrPDB 44 8e-05 2NTV-A nrPDB 41 4e-04 2PD3-A nrPDB 41 5e-04 3ENK-A nrPDB 41 5e-04 2O2Y-A nrPDB 41 7e-04 4OYR-A nrPDB 40 0.001 4LIS-A nrPDB 40 0.001 1Z45-A nrPDB 38 0.005 1UDA-A nrPDB 36 0.018 6ACQ-A nrPDB 34 0.079 3NJ4-A nrPDB 34 0.092 5N2I-A nrPDB 34 0.095 2C20-A nrPDB 33 0.15 1O89-A nrPDB 33 0.16 1DIR-A nrPDB 33 0.17 5GXF-A nrPDB 33 0.22 4K28-A nrPDB 32 0.30 4J6F-A nrPDB 32 0.32 2Q1W-A nrPDB 32 0.37 6BWL-A nrPDB 31 0.49 1JAY-A nrPDB 31 0.56 3VPX-A nrPDB 31 0.61 4UUP-A nrPDB 31 0.65 3F6S-A nrPDB 31 0.73 1OOE-A nrPDB 31 0.78 1I3M-A nrPDB 31 0.78 3PEF-A nrPDB 31 0.83 2NNL-D nrPDB 31 0.84 5K1S-A nrPDB 30 0.92 3PC3-A nrPDB 30 0.94 6ILS-A nrPDB 30 1.0 1ZZE-A nrPDB 30 1.0 3R9I-A nrPDB 30 1.2 4KTT-E nrPDB 30 1.4 2CUK-A nrPDB 30 1.5 5OHX-A nrPDB 30 1.5 2Y6O-A nrPDB 29 1.5 2WWR-A nrPDB 29 1.6 3HDH-A nrPDB 29 1.7 4HEQ-A nrPDB 29 1.9 6C55-A nrPDB 29 2.0 1ZCJ-A nrPDB 29 2.3 4QUK-A nrPDB 29 2.4 3N58-A nrPDB 29 2.4 3OND-A nrPDB 29 2.5 2E7J-A nrPDB 29 2.5 4WOK-A nrPDB 29 2.6 5C1C-A nrPDB 29 2.7 3DC2-A nrPDB 29 2.9 4D3S-A nrPDB 29 2.9 6DEB-A nrPDB 29 3.0 1DB3-A nrPDB 29 3.0 3ZWA-A nrPDB 29 3.1 1F14-A nrPDB 29 3.2 6GBN-A nrPDB 28 3.4 2J5V-A nrPDB 28 3.5 2P4H-X nrPDB 28 4.1 2GO1-A nrPDB 28 4.1 3X2F-A nrPDB 28 4.3 5XW3-A nrPDB 28 4.3 1LU9-A nrPDB 28 4.3 3K6J-A nrPDB 28 4.4 4I1I-A nrPDB 28 5.0 2W21-A nrPDB 28 5.0 4Y4N-A nrPDB 28 5.7 3TX2-A nrPDB 28 6.0 4E0B-A nrPDB 28 6.1 3ORR-A nrPDB 28 6.4 5GMK-P nrPDB 28 6.5 2OHJ-A nrPDB 28 7.1 4OAN-A nrPDB 27 7.6 3KAQ-A nrPDB 27 7.8 1YXY-A nrPDB 27 8.5 >4HBG-A nrPDB Length = 286 Score = 328 bits (841), Expect = 1e-90, Method: Composition-based stats. Identities = 278/278 (100%), Positives = 278/278 (100%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ Sbjct: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC Sbjct: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN Sbjct: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL Sbjct: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET Sbjct: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 >2PNF-A nrPDB Length = 248 Score = 224 bits (570), Expect = 3e-59, Method: Composition-based stats. Identities = 68/271 (25%), Positives = 120/271 (44%), Gaps = 45/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V++VTG+TRGIG+AI +KL G + II G++ E + A + Sbjct: 8 KVSLVTGSTRGIGRAIAEKLASAGSTVIITGTSGERAKAVAEEIAN-------------- 53 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +++ + + + +++ + +++L+N AG+T Sbjct: 54 --------KYGVKAHGVEMNLLSEESINKAFEEIYNLVD---------GIDILVNNAGIT 96 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 ++ L +R + ++++ VN +T ++ M+K + IVNISS+ Sbjct: 97 RDKLFLRMSLLDWEEVLKVNLTGTFLVTQNSLRKMIKQR-----------WGRIVNISSV 145 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G G YS +KA L FT+ LA E+ PRN+ ++PG ++ TDM L E Sbjct: 146 V--GFTGNVGQVNYSTTKAGLIGFTKSLAKELAPRNVLVNAVAPGFIE-TDMTAVLSEEI 202 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 K+ + I +P E+A V L S A Sbjct: 203 KQKYKEQIPLGRFGSPEEVANVVLFLCSELA 233 >3OSU-A nrPDB Length = 246 Score = 220 bits (560), Expect = 5e-58, Method: Composition-based stats. Identities = 59/275 (21%), Positives = 112/275 (40%), Gaps = 45/275 (16%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M A+VTGA+RGIG++I +L ++G + + + + ++ + + S+ Q Sbjct: 1 MKMTKSALVTGASRGIGRSIALQLAEEGYNVAVNYAGSKEKAEAVVEEIKAKGVDSFAIQ 60 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 +A D +K + + +++L+N Sbjct: 61 ANVA----------------------DADEVKAMIKEVV---------SQFGSLDVLVNN 89 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T+++L +R + D+++ N M++ + I+N Sbjct: 90 AGITRDNLLMRMKEQEWDDVIDTNLKGVFNCIQKATPQMLRQR-----------SGAIIN 138 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 +SS++ G + PG + Y A+KA + T+ A E+ R I ++PG + +DM L Sbjct: 139 LSSVV--GAVGNPGQANYVATKAGVIGLTKSAARELASRGITVNAVAPGFI-VSDMTDAL 195 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E KE + I + +IA V L S A Sbjct: 196 SDELKEQMLTQIPLARFGQDTDIANTVAFLASDKA 230 >2C07-A nrPDB Length = 285 Score = 218 bits (556), Expect = 1e-57, Method: Composition-based stats. Identities = 66/272 (24%), Positives = 112/272 (41%), Gaps = 46/272 (16%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 VA+VTGA RGIG+ I + L + I + T++S + + Sbjct: 44 NKVALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIK-------------- 89 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 YES + + + + + V++L+N AG+ Sbjct: 90 ---------SFGYESSGYAGDVSKKEEISEVINKIL---------TEHKNVDILVNNAGI 131 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 T+++L +R + +D++ N S +T K M+ ++ I+NISS Sbjct: 132 TRDNLFLRMKNDEWEDVLRTNLNSLFYITQPISKRMINNR-----------YGRIINISS 180 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 I+ G G + YS+SKA + FT+ LA E+ RNI I+PG + +DM + + Sbjct: 181 IV--GLTGNVGQANYSSSKAGVIGFTKSLAKELASRNITVNAIAPGFI-SSDMTDKISEQ 237 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 K+ + I A P E+A L S + Sbjct: 238 IKKNIISNIPAGRMGTPEEVANLACFLSSDKS 269 >3LYL-A nrPDB Length = 247 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 66/271 (24%), Positives = 118/271 (43%), Gaps = 46/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTGA+RGIG + L KG + + +++ S E+ Sbjct: 6 KVALVTGASRGIGFEVAHALASKGATVVGTATSQASAEK--------------------- 44 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 F+ +++ + D ++ ++ + +++L+N AG+T Sbjct: 45 --FENSMKEKGFKARGLVLNISDIESIQNFFAEI---------KAENLAIDILVNNAGIT 93 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + + Q ++N N S M+ C++ MMK + I++I S+ Sbjct: 94 RDNLMMRMSEDEWQSVINTNLSSIFRMSKECVRGMMKKR-----------WGRIISIGSV 142 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G PG + Y A+KA + F++ LA E+ RNI ++PG + TDM L E Sbjct: 143 V--GSAGNPGQTNYCAAKAGVIGFSKSLAYEVASRNITVNVVAPGFIA-TDMTDKLTDEQ 199 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 K + I + P +IA V L S A Sbjct: 200 KSFIATKIPSGQIGEPKDIAAAVAFLASEEA 230 >2HQ1-A nrPDB Length = 247 Score = 211 bits (536), Expect = 3e-55, Method: Composition-based stats. Identities = 73/271 (26%), Positives = 118/271 (43%), Gaps = 45/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 AIVTG++RG+GKAI KL G + ++ GS + + Sbjct: 6 KTAIVTGSSRGLGKAIAWKLGNMGANIVLNGSPASTSLDATAE----------------- 48 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +FK + D K+ ++ T D + +++L+N AG+T Sbjct: 49 -EFKAAGINVVVAKGD----VKNPEDVENMVKTAMDAFGR---------IDILVNNAGIT 94 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L ++ + D++N N S T K M+K + I+NI+SI Sbjct: 95 RDTLMLKMSEKDWDDVLNTNLKSAYLCTKAVSKIMLKQK-----------SGKIINITSI 143 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 +G + G + Y+ASKA L FT+ +A E + I C ++PG++K TDM LP + Sbjct: 144 --AGIIGNAGQANYAASKAGLIGFTKSIAKEFAAKGIYCNAVAPGIIK-TDMTDVLPDKV 200 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 KEM I P E+A V L S + Sbjct: 201 KEMYLNNIPLKRFGTPEEVANVVGFLASDDS 231 >4JRO-A nrPDB Length = 271 Score = 210 bits (535), Expect = 4e-55, Method: Composition-based stats. Identities = 62/271 (22%), Positives = 103/271 (38%), Gaps = 45/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTG +RGIG+ I L ++G + + Sbjct: 30 KVAVVTGGSRGIGRDIAINLAKEGANIFFNYNGSPEAAEETAKLVAEHGV---------- 79 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +E K + + F ER V++L+N AG+T Sbjct: 80 ----------------EVEAMKANVAIAEDVDAFFKQA-----IERFGRVDILVNNAGIT 118 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + D++N+N T + MMK + I+N++S+ Sbjct: 119 RDNLLMRMKEDEWDDVININLKGTFLCTKAVSRTMMKQRA-----------GKIINMASV 167 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G + G + Y ASKA + T+ A E+ PR I ++PG + TDM L + Sbjct: 168 V--GLIGNAGQANYVASKAGVIGLTKTTARELAPRGINVNAVAPGFI-TTDMTDKLDEKT 224 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 KE + I +IA V L S + Sbjct: 225 KEAMLAQIPLGAYGTTEDIANAVLFLASDAS 255 >3RSH-A nrPDB Length = 251 Score = 209 bits (532), Expect = 1e-54, Method: Composition-based stats. Identities = 67/271 (24%), Positives = 117/271 (43%), Gaps = 49/271 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTGA+RGIGKAI + L ++G I +++ + + G G++ Sbjct: 13 KVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMAL------- 65 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + ++ + D V++L+N AG+T Sbjct: 66 -------------------NVTNPESIEAVLKAITDEF---------GGVDILVNNAGIT 97 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + DIM N S ++ ++ MMK ++ I+N+ S+ Sbjct: 98 RDNLLMRMKEEEWSDIMETNLTSIFRLSKAVLRGMMKKRQ-----------GRIINVGSV 146 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G M G + Y+A+KA + FT+ +A E+ R + T++PG ++ TDM + L E Sbjct: 147 V--GTMGNAGQANYAAAKAGVIGFTKSMAREVASRGVTVNTVAPGFIE-TDMTKALNDEQ 203 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + A P EIA V L S A Sbjct: 204 RTATLAQVPAGRLGDPREIASAVAFLASPEA 234 >3FTP-A nrPDB Length = 270 Score = 208 bits (528), Expect = 2e-54, Method: Composition-based stats. Identities = 69/270 (25%), Positives = 113/270 (41%), Gaps = 46/270 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VAIVTGA+RGIG+AI +L ++G I +T+ E Q Sbjct: 30 VAIVTGASRGIGRAIALELARRGAMVIGTATTEAGAEGIGAAFKQAG------------- 76 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 E + D + + +N+L+N AG+TQ Sbjct: 77 ----------LEGRGAVLNVNDATAVDALVESTLKEF---------GALNVLVNNAGITQ 117 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L++R + +++ N + ++ ++ MMK++ IVNI+S++ Sbjct: 118 DQLAMRMKDDEWDAVIDTNLKAVFRLSRAVLRPMMKAR-----------GGRIVNITSVV 166 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G PG Y+A+KA ++ T LA E+ R I ++PG + TDM + LP E + Sbjct: 167 --GSAGNPGQVNYAAAKAGVAGMTRALAREIGSRGITVNCVAPGFID-TDMTKGLPQEQQ 223 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 L+ I +P +IA V L S A Sbjct: 224 TALKTQIPLGRLGSPEDIAHAVAFLASPQA 253 >2PH3-A nrPDB Length = 245 Score = 208 bits (528), Expect = 3e-54, Method: Composition-based stats. Identities = 68/269 (25%), Positives = 111/269 (41%), Gaps = 44/269 (16%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TGA+RGIG+AI +L + G + I + + + A ++ Sbjct: 4 ALITGASRGIGRAIALRLAEDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGANLLE 63 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + + + E ++ L+N AG+T++ Sbjct: 64 AEAATALVHQAA------------------------------EVLGGLDTLVNNAGITRD 93 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 +L VR + ++ N + T +K MMK++ IVNI+S++ Sbjct: 94 TLLVRMKDEDWEAVLEANLSAVFRTTREAVKLMMKARF-----------GRIVNITSVV- 141 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 G + PG + Y ASKA L FT +A E R I ++PG ++ T+M + LP E KE Sbjct: 142 -GILGNPGQANYVASKAGLIGFTRAVAKEYAQRGITVNAVAPGFIE-TEMTERLPQEVKE 199 Query: 247 MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I A P E+AE V L S A Sbjct: 200 AYLKQIPAGRFGRPEEVAEAVAFLVSEKA 228 >5CDY-A nrPDB Length = 244 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 66/271 (24%), Positives = 117/271 (43%), Gaps = 49/271 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 +A+VTGA+RGIG+AI + L ++G I ++++ E + G+ GL + Sbjct: 6 KIALVTGASRGIGRAIAELLVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVDPTS 65 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 ID ++ V++L+N AG+T Sbjct: 66 IDTVLATIRAEF-----------------------------------GEVDILVNNAGIT 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + QDI++ N S ++ ++ MMK + I+ I S+ Sbjct: 91 RDNLLMRMKDDEWQDIIDTNLTSVFRLSKAVMRAMMKKRF-----------GRIITIGSV 139 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G M G Y+A+KA + F++ LA E+ R I ++PG ++ TDM + L + Sbjct: 140 V--GTMGNAGQVNYAAAKAGVIGFSKSLAREVASRGITVNVVAPGFIE-TDMTRTLTDDQ 196 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + A+ EIA V L S A Sbjct: 197 RAGILAQVPANRLGDAKEIASAVAFLASDEA 227 >2UVD-A nrPDB Length = 246 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 64/275 (23%), Positives = 111/275 (40%), Gaps = 45/275 (16%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA+VTGA+RGIG+AI L ++G + ++ + E +D + + + Sbjct: 1 MLKGKVALVTGASRGIGRAIAIDLAKQGANVVVNYAGNEQKANEVVDEIKKLGSDAIAVR 60 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 +A + + D + V++L+N Sbjct: 61 ADVA----------------------NAEDVTNMVKQTVDVFGQ---------VDILVNN 89 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T+++L +R + ++N N T ++MM+ + IVN Sbjct: 90 AGVTKDNLLMRMKEEEWDTVINTNLKGVFLCTKAVSRFMMRQR-----------HGRIVN 138 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 I+S++ G PG + Y A+KA + T+ A E+ RNI I+PG + TDM L Sbjct: 139 IASVV--GVTGNPGQANYVAAKAGVIGLTKTSAKELASRNITVNAIAPGFIA-TDMTDVL 195 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 K + + I A+ +IA V S + Sbjct: 196 DENIKAEMLKLIPAAQFGEAQDIANAVTFFASDQS 230 >3EMK-A nrPDB Length = 246 Score = 203 bits (517), Expect = 5e-53, Method: Composition-based stats. Identities = 69/269 (25%), Positives = 110/269 (40%), Gaps = 49/269 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGAT G+G+AI + L +G + G+ +E ++ A + G+ Sbjct: 10 ALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPA--------- 60 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 DR +K E V++L+N AG+T++ Sbjct: 61 -----------------NLSDREAVKALGQKA---------EEEMGGVDILVNNAGITRD 94 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 L VR + ++ VN S +T MM+ + I+NI+SI+ Sbjct: 95 GLFVRMSDEDWDAVLTVNLTSVFNLTRELTHPMMRRR-----------NGRIINITSIV- 142 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 G PG + Y ASKA L F++ LA E+ RN+ I+PG ++ + M L + K+ Sbjct: 143 -GVTGNPGQANYCASKAGLIGFSKSLAQEIASRNVTVNCIAPGFIE-SAMTGKLNEKQKD 200 Query: 247 MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I A+IA V L S A Sbjct: 201 AIMGNIPMKRMGVGADIAAAVVYLASDEA 229 >3EZL-A nrPDB Length = 256 Score = 203 bits (515), Expect = 9e-53, Method: Composition-based stats. Identities = 68/270 (25%), Positives = 111/270 (41%), Gaps = 45/270 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A VTG GIG +ICQ+L + G + G S R + Q A+ Sbjct: 15 IAYVTGGMGGIGTSICQRLHKDGFRVV-AGCGPNSPRRV----------KWLEDQKALGF 63 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 DF Y D KQ + + +++L+N AG+T+ Sbjct: 64 DF-----------YASEGNVGDWDSTKQAFDKV---------KAEVGEIDVLVNNAGITR 103 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + + T Q +++ N S +T I M+ + I+NISS+ Sbjct: 104 DVVFRKMTREDWQAVIDTNLTSLFNVTKQVIDGMV-----------ERGWGRIINISSV- 151 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G+ G + YS +KA + FT LA E+ + + T+SPG + GTDM++ + + Sbjct: 152 -NGQKGQFGQTNYSTAKAGIHGFTMSLAQEVATKGVTVNTVSPGYI-GTDMVKAIRPDVL 209 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E + TI +P EI V L S + Sbjct: 210 EKIVATIPVRRLGSPDEIGSIVAWLASEES 239 >3GRP-A nrPDB Length = 266 Score = 202 bits (513), Expect = 1e-52, Method: Composition-based stats. Identities = 72/269 (26%), Positives = 111/269 (41%), Gaps = 49/269 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGAT GIG+AI + +G + G+ ++ ++ A D G+ S Sbjct: 30 ALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSA--------- 80 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 DR +KQ +++L+N AG+T++ Sbjct: 81 -----------------NLSDRKSIKQLAEVA---------EREMEGIDILVNNAGITRD 114 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 L VR D++ VN + T+T I MM+ + I+NI+SI+ Sbjct: 115 GLFVRMQDQDWDDVLAVNLTAASTLTRELIHSMMRRR-----------YGRIINITSIV- 162 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 G + PG + Y A+KA L F++ LA E+ RNI I+PG +K + M L + KE Sbjct: 163 -GVVGNPGQTNYCAAKAGLIGFSKALAQEIASRNITVNCIAPGFIK-SAMTDKLNEKQKE 220 Query: 247 MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I EIA L S A Sbjct: 221 AIMAMIPMKRMGIGEEIAFATVYLASDEA 249 >1Q7C-A nrPDB Length = 244 Score = 198 bits (504), Expect = 1e-51, Method: Composition-based stats. Identities = 63/271 (23%), Positives = 113/271 (41%), Gaps = 49/271 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 +A+VTGA+RGIG+AI + L +G I +++ + + G GL Sbjct: 6 KIALVTGASRGIGRAIAETLAARGAKVIGTATSENGAQAISDYLGANGKGL--------- 56 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + D ++ + + V++L+N AG+T Sbjct: 57 -----------------MLNVTDPASIESVLEKIRAEFGE---------VDILVNNAGIT 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + DI+ N S ++ ++ MMK + I+ I S+ Sbjct: 91 RDNLLMRMKDEEWNDIIETNLSSVFRLSKAVMRAMMKKR-----------HGRIITIGSV 139 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G M G + ++A+KA L F++ LA E+ R I ++PG ++ TDM + L + Sbjct: 140 V--GTMGNGGQANFAAAKAGLIGFSKSLAREVASRGITVNVVAPGFIE-TDMTRALSDDQ 196 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + A EIA V L S A Sbjct: 197 RAGILAQVPAGRLGGAQEIANAVAFLASDEA 227 >4CQL-A nrPDB Length = 261 Score = 198 bits (503), Expect = 2e-51, Method: Composition-based stats. Identities = 62/272 (22%), Positives = 110/272 (40%), Gaps = 37/272 (13%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 +A+VTGA GIG+A+ +L +G + + + + T G S R Sbjct: 11 SALALVTGAGSGIGRAVSVRLAGEGATVAACDLDRAAAQETVRLLGGPGSKEGPPRGNHA 70 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 A D E R L+Q + +++++CAG+ Sbjct: 71 AFQ------------ADVSEARAARCLLEQVQACF------------SRPPSVVVSCAGI 106 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 TQ+ + + ++ VN +T + ++ + R +I+NISS Sbjct: 107 TQDEFLLHMSEDDWDKVIAVNLKGTFLVTQAAAQALVSN----------GCRGSIINISS 156 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 I+ GK+ G + Y+ASKA + T+ A E+ IRC ++ PG + T M Q +P + Sbjct: 157 IV--GKVGNVGQTNYAASKAGVIGLTQTAARELGRHGIRCNSVLPGFIA-TPMTQKVPQK 213 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + I P ++A+ V L S + Sbjct: 214 VVDKITEMIPMGHLGDPEDVADVVAFLASEDS 245 >4KMS-A nrPDB Length = 249 Score = 198 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 69/273 (25%), Positives = 113/273 (41%), Gaps = 49/273 (17%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 +AIVTG TRGIGKA +L KGL+ + + + +++ + +C Sbjct: 9 MSEIAIVTGGTRGIGKATALELKNKGLTVVANFFSNYDAAK------EMEEKYGIKTKCW 62 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 DF++ + K E + V++L+N AG Sbjct: 63 NVADFEECRQAV-----------------------------KEIEEEFKKPVSILVNNAG 93 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 +T++ + R + D++NVN S M++ ++ M IVNIS Sbjct: 94 ITKDKMLHRMSHQDWNDVINVNLNSCFNMSSSVMEQMRNQD-----------YGRIVNIS 142 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 SI + + G + YSA+KA + FT+ LA E +NI I+PG + T+M+ +P Sbjct: 143 SI--NAQAGQVGQTNYSAAKAGIIGFTKALARETASKNITVNCIAPGYIA-TEMVGAVPE 199 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + +I P EIA V L A Sbjct: 200 DVLAKIINSIPKKRLGQPEEIARAVAFLVDENA 232 >3F9I-A nrPDB Length = 249 Score = 198 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 63/273 (23%), Positives = 109/273 (39%), Gaps = 53/273 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 +++TGA+ GIG AI + L + G II GS +E ++ Sbjct: 13 TGKTSLITGASSGIGSAIARLLHKLGSKVIISGSNEEKLKSLGNALK------------- 59 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 D K++ S L + +++L+ AG Sbjct: 60 -----------------DNYTIEVCNLANKEECSNLI---------SKTSNLDILVCNAG 93 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 +T ++L++R ++++N + + IK M++ + I+NIS Sbjct: 94 ITSDTLAIRMKDQDFDKVIDINLKANFILNREAIKKMIQKR-----------YGRIINIS 142 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 SI+ G PG + Y ASKA L T+ L+ E+ R I ++PG +K +DM L Sbjct: 143 SIV--GIAGNPGQANYCASKAGLIGMTKSLSYEVATRGITVNAVAPGFIK-SDMTDKLNE 199 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + +E + + I P ++A V L S A Sbjct: 200 KQREAIVQKIPLGTYGIPEDVAYAVAFLASNNA 232 >3VZS-A nrPDB Length = 257 Score = 197 bits (499), Expect = 6e-51, Method: Composition-based stats. Identities = 64/270 (23%), Positives = 104/270 (38%), Gaps = 45/270 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A VTG GIG AICQ+L + G + Sbjct: 16 IAYVTGGMGGIGTAICQRLAKDGFRVV----------------------------AGCGP 47 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + + WL+ + G ++ + ST V++LIN AG+T+ Sbjct: 48 NSPRREKWLEQQKALGFDFIASEGNVADWDST---KTAFDKVKSEVGEVDVLINNAGITR 104 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + + T + +++ N S +T I M IVNISS+ Sbjct: 105 DVVFRKMTRADWDAVIDTNLTSLFNVTKQVIDGM-----------ADRGWGRIVNISSV- 152 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G+ G + YS +KA L FT LA E+ + + T+SPG + TDM++ + + Sbjct: 153 -NGQKGQFGQTNYSTAKAGLHGFTMALAQEVATKGVTVNTVSPGYIA-TDMVKAIRQDVL 210 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + TI P EIA L S + Sbjct: 211 DKIVATIPVKRLGLPEEIASICAWLSSEES 240 >4M8S-A nrPDB Length = 248 Score = 196 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 63/271 (23%), Positives = 109/271 (40%), Gaps = 48/271 (17%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 +A+VTGA+RGIG AI L G I +++ + Q Sbjct: 9 KIALVTGASRGIGAAIADTLAAAGAKVIGTATSESGAAAISERLAQWGG----------- 57 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + ++ + + K +++L+N AG+T Sbjct: 58 --------------EGRVLNSAEPETVENLIADIEKTFGK---------LDILVNNAGIT 94 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L +R + DIM VN S + ++ MMK + I+NI+S+ Sbjct: 95 RDNLLMRMKEEEWDDIMQVNLKSVFRASKAVLRGMMKQRA-----------GRIINITSV 143 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G M G + Y+A+KA L F++ +A E+ R I ++PG + TDM + LP E Sbjct: 144 V--GVMGNAGQTNYAAAKAGLIGFSKSMAREVGSRGITVNCVAPGFID-TDMTRALPEET 200 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 ++ +IA+ V L S A Sbjct: 201 RQTFTAQTALGRFGDAQDIADAVLFLASDQA 231 >4BO1-A nrPDB Length = 269 Score = 195 bits (494), Expect = 3e-50, Method: Composition-based stats. Identities = 70/271 (25%), Positives = 112/271 (41%), Gaps = 46/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTGA+RGIG+AI +L + G I ++ E+ A A Sbjct: 28 KVALVTGASRGIGQAIALELGRLGAVVIGTATSASGAEKIAETLK--------------A 73 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + LD S + + + + +++N AG+T Sbjct: 74 NGVEGAGLVLDVSSDESVAATLEHIQ------------------QHLGQPLIVVNNAGIT 115 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++L VR + D++N N S ++ ++ M K++ I+NI S+ Sbjct: 116 RDNLLVRMKDDEWFDVVNTNLNSLYRLSKAVLRGMTKAR-----------WGRIINIGSV 164 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 + G M G + Y+A+KA L FT LA E+ R I ++PG + TDM + LP Sbjct: 165 V--GAMGNAGQTNYAAAKAGLEGFTRALAREVGSRAITVNAVAPGFID-TDMTRELPEAQ 221 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +E L I EIA+ V L S A Sbjct: 222 REALLGQIPLGRLGQAEEIAKVVGFLASDGA 252 >3WOH-A nrPDB Length = 251 Score = 194 bits (492), Expect = 4e-50, Method: Composition-based stats. Identities = 59/271 (21%), Positives = 109/271 (40%), Gaps = 47/271 (17%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTG +RG+G+A+ +L + G + I+ + +S + + G + +C + Sbjct: 12 KVALVTGGSRGLGRAMALRLARDGAAVAIVYVSDDSSAKETQGEIERLGGTARSYRCDV- 70 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D + + + V++L+N AG+ Sbjct: 71 ---------------------SDAEQVTRCVKAV---------TADLGPVDILVNNAGII 100 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 ++ L+ +MN N C ++ + +I+NISS+ Sbjct: 101 RDGLAASIKDEDYDAVMNTNLKGAFLFIKACYFGFIRKR-----------SGSIINISSV 149 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 SG G + Y+++KA L T+ +A E+ RN+RC ++PGL+ TDM Q+L ++ Sbjct: 150 --SGVFGSAGQANYASAKAGLIGLTKSIAKELAERNVRCNAVAPGLIA-TDMTQDLVDDS 206 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 K + P E+A V L + Sbjct: 207 KR--LDPVPMRRFGRPDEVAGLVAFLAGDES 235 >2CDH-G nrPDB Length = 244 Score = 190 bits (483), Expect = 5e-49, Method: Composition-based stats. Identities = 61/272 (22%), Positives = 111/272 (40%), Gaps = 45/272 (16%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 PV +VTGA+RGIGKAI L + G ++ + + + G + + Sbjct: 1 SPVVVVTGASRGIGKAIALSLGKAGCKVLVNYARSAKAAEEVSKQIEAYGGQAITFGGDV 60 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + + ++ T D +++++N AG+ Sbjct: 61 SKE----------------------ADVEAMMKTAIDA---------WGTIDVVVNNAGI 89 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 T+++L +R SQ +++++N T K MMK ++ I+NI+S Sbjct: 90 TRDTLLIRMKKSQWDEVIDLNLTGVFLCTQAATKIMMKKRK-----------GRIINIAS 138 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 ++ G + G + Y+A+KA + F++ A E RNI + PG + +DM L + Sbjct: 139 VV--GLIGNIGQANYAAAKAGVIGFSKTAAREGASRNINVNVVCPGFIA-SDMTAKLGED 195 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 ++ + TI T P +A V L A Sbjct: 196 MEKKILGTIPLGRTGQPENVAGLVEFLALSPA 227 >4NBV-A nrPDB Length = 246 Score = 190 bits (481), Expect = 7e-49, Method: Composition-based stats. Identities = 57/270 (21%), Positives = 104/270 (38%), Gaps = 46/270 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VAI+TGA GIG A Q+ + G ++ + + A + +S R Sbjct: 7 VAIITGAAAGIGFATAQRFAEDGAIVVLCDVQEARVREAAARLAATGATVSAYRV----- 61 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 R + + + + V++L+N AG+T+ Sbjct: 62 ------------------DVTRRDEVDAMVAAVLAAHQR---------VDILVNNAGITK 94 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++ + T +Q +++VN M + + I+N SS++ Sbjct: 95 DARLAKMTEAQFDAVIDVNLKGVFNCAQAVAGLMTEQ-----------GKGVILNASSVV 143 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G G + Y+ASK + FT+ A E+ P+ +R + PG V T+++Q +P + Sbjct: 144 --GLYGNFGQTNYAASKFGVIGFTKTWARELGPKGVRVNAVCPGFVN-TEILQTVPDKVL 200 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + + PAEIA L S A Sbjct: 201 DGMTSSCWLRRLAEPAEIASIYAFLASDDA 230 >4RZH-A nrPDB Length = 247 Score = 190 bits (481), Expect = 8e-49, Method: Composition-based stats. Identities = 65/273 (23%), Positives = 115/273 (42%), Gaps = 48/273 (17%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VA+VTGA+RGIGKA L G+ ++ + + + G + Q Sbjct: 5 TAQVALVTGASRGIGKATALALAATGMKVVVNYAQSSTAADAVVAEIIANGGEAIAVQAN 64 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 +A + + Q T D ++ +++L+N AG Sbjct: 65 VA----------------------NADEVDQLIKTTLDKFSR---------IDVLVNNAG 93 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 +T+++L +R Q ++++N T K M+K + I+NI+ Sbjct: 94 ITRDTLLLRMKLEDWQAVIDLNLTGVFLCTKAVSKLMLKQK-----------SGRIINIT 142 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S+ +G M PG + YSA+KA + FT+ +A E+ R + ++PG + TDM +NL Sbjct: 143 SV--AGMMGNPGQANYSAAKAGVIGFTKTVAKELASRGVTVNAVAPGFIA-TDMTENLNA 199 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E + + I + P E+A + L + A Sbjct: 200 EP---ILQFIPLARYGQPEEVAGTIRFLATDPA 229 >4DMM-A nrPDB Length = 269 Score = 189 bits (480), Expect = 9e-49, Method: Composition-based stats. Identities = 62/270 (22%), Positives = 114/270 (42%), Gaps = 48/270 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A+VTGA+RGIG+AI +L G + ++ + G ++ + ++ Sbjct: 30 IALVTGASRGIGRAIALELAAAGAKVAVNYASSAGAADEVVAAIAAAGGEAFAVKADVSQ 89 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + ++ ++ + ER +++L+N AG+T+ Sbjct: 90 E----------------------SEVEALFAAVI---------ERWGRLDVLVNNAGITR 118 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++L +R Q ++++N + K M+K + I+NI+S++ Sbjct: 119 DTLLLRMKRDDWQSVLDLNLGGVFLCSRAAAKIMLKQR-----------SGRIINIASVV 167 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 G+M PG + YSA+KA + T+ +A E+ R I ++PG + TDM L A Sbjct: 168 --GEMGNPGQANYSAAKAGVIGLTKTVAKELASRGITVNAVAPGFIA-TDMTSEL---AA 221 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E L I AE+A V L + A Sbjct: 222 EKLLEVIPLGRYGEAAEVAGVVRFLAADPA 251 >4K6F-A nrPDB Length = 255 Score = 188 bits (476), Expect = 3e-48, Method: Composition-based stats. Identities = 59/271 (21%), Positives = 105/271 (38%), Gaps = 46/271 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A+VTG G+G+A+ +L G ++ S + + A Sbjct: 13 IAVVTGGMGGLGEAVSIRLNDAGHRVVVTYSPNNT-----------GADRWLTEMHAAGR 61 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 +F +P +D +D + ++ V++L+N AG+T+ Sbjct: 62 EFHAYP--VDVADHDSCQQCIEK------------------IVRDVGPVDILVNNAGITR 101 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + ++ N S MT M++ IVNISS+ Sbjct: 102 DMTLRKLDKVNWDAVIRTNLDSVFNMTKPVCDGMVER-----------GWGRIVNISSV- 149 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +G G + Y+A+KA + FT+ LA E+ + + T+SPG + T M+ +P + Sbjct: 150 -NGSKGSVGQTNYAAAKAGMHGFTKSLALEIARKGVTVNTVSPGYLA-TKMVTAIPQDIL 207 Query: 246 E-MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + I A P E+A V L S A Sbjct: 208 DTKILPQIPAGRLGKPEEVAALVAYLCSEEA 238 >1YXM-A nrPDB Length = 303 Score = 185 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 56/273 (20%), Positives = 92/273 (33%), Gaps = 44/273 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VAIVTG GIGKAI ++L + G + +I E ++ A + R I Sbjct: 20 VAIVTGGATGIGKAIVKELLELGSNVVIASRKLERLKSAADELQANLPPTKQARVIPIQC 79 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + + + + + D K +N L+N G Sbjct: 80 NIR------------------NEEEVNNLVKSTLDTFGK---------INFLVNNGGGQF 112 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 S + ++ ++ N M MK +IVNI + Sbjct: 113 LSPAEHISSKGWHAVLETNLTGTFYMCKAVYSSWMKEH-----------GGSIVNI---I 158 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 K P A++A + T+ LA E IR ++PG++ ++N + Sbjct: 159 VPTKAGFPLAVHSGAARAGVYNLTKSLALEWACSGIRINCVAPGVIYSQTAVENYGSWGQ 218 Query: 246 EMLE---RTIGASGTSAPAEIAEEVWSLYSRTA 275 E + I A P E++ V L S A Sbjct: 219 SFFEGSFQKIPAKRIGVPEEVSSVVCFLLSPAA 251 >5VT6-A nrPDB Length = 269 Score = 185 bits (468), Expect = 2e-47, Method: Composition-based stats. Identities = 63/276 (22%), Positives = 109/276 (39%), Gaps = 46/276 (16%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA VTG G+G AI ++L G++ + S + T + Sbjct: 22 MQAKRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVST-----------WLMHE 70 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 DFK + +D ++ E ++ V++LIN Sbjct: 71 RDAGRDFKAYA--VDVADFESCERCAEK------------------VLADFGKVDVLINN 110 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+T+++ ++ T +M + + +T I M++ + IVN Sbjct: 111 AGITRDATFMKMTKGDWDAVMRTDLDAMFNVTKQFIAGMVERRF-----------GRIVN 159 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 I S+ +G G + Y+++KA + FT+ LA E R I T+SPG + T M++ + Sbjct: 160 IGSV--NGSRGAFGQANYASAKAGIHGFTKTLALETAKRGITVNTVSPGYLA-TAMVEAV 216 Query: 241 PVEAKE-MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 P + E + I P E+A + L S A Sbjct: 217 PQDVLEAKILPQIPVGRLGRPDEVAALIAFLCSDDA 252 >4NBT-A nrPDB Length = 240 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 54/273 (19%), Positives = 107/273 (39%), Gaps = 57/273 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA++TG +G+G+AI ++G I + ++ L Sbjct: 7 KVAVITGGAKGLGQAIALAYAEEGAKVIAGDLGDLTYSHPNVEGMYLN------------ 54 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D +++ Y ++ D K +++L+N AG+T Sbjct: 55 --------------------VTDVTGVEKFYQSVIDKYGK---------IDILVNNAGIT 85 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++++ + T +Q +++VN +T + M + +I+NISS+ Sbjct: 86 KDAMTRKMTEAQWDAVIDVNLKGVFNLTRLVGPQMQ-----------TNGYGSIINISSV 134 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRN--IRCFTISPGLVKGTDMIQNLPV 242 + G G + Y+A+KA + T A E + +R I+PG + TD+++ +P Sbjct: 135 V--GVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIM-TDILKTVPQ 191 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + P EIA+ L S A Sbjct: 192 DLLDKFAALTMLNRLGQPEEIAKVALFLASDDA 224 >2NM0-A nrPDB Length = 253 Score = 184 bits (466), Expect = 4e-47, Method: Composition-based stats. Identities = 63/274 (22%), Positives = 99/274 (36%), Gaps = 57/274 (20%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 H +VTG RGIG AI + G I + E E + Sbjct: 19 HMSRSVLVTGGNRGIGLAIARAFADAGDKVAITYRSGEPPEGFLAVKCD----------- 67 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 D ++Q Y + E V +LI A Sbjct: 68 -----------------------ITDTEQVEQAYKEI---------EETHGPVEVLIANA 95 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 G+T++ L +R + ++ N + + M+++++ +V I Sbjct: 96 GVTKDQLLMRMSEEDFTSVVETNLTGTFRVVKRANRAMLRAKK-----------GRVVLI 144 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 SS++ G + G + Y+ASKA L F LA E+ RNI ++PG V TDM + L Sbjct: 145 SSVV--GLLGSAGQANYAASKAGLVGFARSLARELGSRNITFNVVAPGFVD-TDMTKVLT 201 Query: 242 VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E + + + + P EIA V L S A Sbjct: 202 DEQRANIVSQVPLGRYARPEEIAATVRFLASDDA 235 >6NRP-A nrPDB Length = 263 Score = 181 bits (460), Expect = 2e-46, Method: Composition-based stats. Identities = 59/268 (22%), Positives = 100/268 (37%), Gaps = 47/268 (17%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG++RGIGKAI +L + G + ++++ + + Sbjct: 28 LVTGSSRGIGKAIALQLAKAGFDVTVHARSRQAEAEQVVQ------------------EI 69 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 + Y +D E + L+Q ++ AGLT + Sbjct: 70 QALGQNSHYLMFDVNERQTVQQILEQDVEQHGGFYG-------------VVLNAGLTHDG 116 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 T ++++ + + I M+ ++ IV +SS+ S Sbjct: 117 AFPALTDQDWDEVISTSLDGFYNVLKPLIMPMIHLRK----------GGRIVTLSSV--S 164 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G M G YSA+KA L T+ LA E+ R I ++PGL++ T+M+ E KE Sbjct: 165 GIMGNRGQVNYSAAKAGLIGATKALALELAKRKITVNCVAPGLIE-TEMVT---DEVKEH 220 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I E+A V L S A Sbjct: 221 ALKMIPLQRMGQVDEVASVVKFLCSDEA 248 >4CQM-B nrPDB Length = 244 Score = 179 bits (454), Expect = 1e-45, Method: Composition-based stats. Identities = 67/272 (24%), Positives = 106/272 (38%), Gaps = 52/272 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 V V G +RGIG+A+ Q + +KG ++ E + A D G S C Sbjct: 8 MDKVCAVFGGSRGIGRAVAQLMARKGYRLAVIARNLEGAKAAAGDLGGDHLAFS----CD 63 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 +A + + + E + VN L+N AG Sbjct: 64 VAKEHDVQNTFEELEKH-------------------------------LGRVNFLVNAAG 92 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + ++ L VRT + ++ N + + ++ M++ Q +IVN+ Sbjct: 93 INRDGLLVRTKTEDMVSQLHTNLLGSMLTCKAAMRTMIQQQ-----------GGSIVNVG 141 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 SI+ G G SVYSASK L F+ LA E+ + IR ++PG V TDM ++L Sbjct: 142 SIV--GLKGNSGQSVYSASKGGLVGFSRALAKEVARKKIRVNVVAPGFVH-TDMTKDLKE 198 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRT 274 E L++ I E+A V L Sbjct: 199 ---EHLKKNIPLGRFGETIEVAHAVVFLLESP 227 >4IIN-A nrPDB Length = 271 Score = 176 bits (447), Expect = 7e-45, Method: Composition-based stats. Identities = 58/266 (21%), Positives = 104/266 (39%), Gaps = 45/266 (16%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++TGA++GIG I + L GL I + + + + + + + A + Sbjct: 33 LITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKFDAASES 92 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 DG ++ L+N AG+ ++ Sbjct: 93 DFIEAIQTIVQSDG-------------------------------GLSYLVNNAGVVRDK 121 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 L+++ +++ N S +K M KS+ ++VN++SI+ Sbjct: 122 LAIKMKTEDFHHVIDNNLTSAFIGCREALKVMSKSRF-----------GSVVNVASII-- 168 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G+ G + YSASK + ++ A E RNIR +++PG ++ TDM NL E K Sbjct: 169 GERGNMGQTNYSASKGGMIAMSKSFAYEGALRNIRFNSVTPGFIE-TDMNANLKDELKAD 227 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSR 273 + I + + E+AE V L S Sbjct: 228 YVKNIPLNRLGSAKEVAEAVAFLLSD 253 >4IS3-A nrPDB Length = 268 Score = 176 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 60/271 (22%), Positives = 101/271 (37%), Gaps = 44/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V I+TG TRGIG A + G I G T+E ++ +L Sbjct: 26 KVTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLKELY------------ 73 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + D S D + + ++ ++++IN AG+T Sbjct: 74 PEEEVLGFAPDLTSRDAVMAAVGQVA------------------QKYGRLDVMINNAGIT 115 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 ++ R + + + IM++N + M +++ I+N +S+ Sbjct: 116 SNNVFSRVSEEEFKHIMDINVTGVFNGAWCAYQCMKDAKK-----------GVIINTASV 164 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 +G Y ASKA++ T L E+ +NIR ++PG+V TDM P E Sbjct: 165 --TGIFGSLSGVGYPASKASVIGLTHGLGREIIRKNIRVVGVAPGVVN-TDMTNGNPPEI 221 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E + + P EIA L S A Sbjct: 222 MEGYLKALPMKRMLEPEEIANVYLFLASDLA 252 >3O4R-A nrPDB Length = 261 Score = 173 bits (438), Expect = 7e-44, Method: Composition-based stats. Identities = 61/275 (22%), Positives = 107/275 (38%), Gaps = 49/275 (17%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 VA+VT +T GIG AI ++L Q G ++ ++++++ ++ Sbjct: 15 NKVALVTASTDGIGFAIARRLAQDGAHVVVSSRKQQNVDQAVATLQGEGLSVTGT----- 69 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + +DR L L +++L++ A + Sbjct: 70 ---------------VCHVGKAEDRERLVATAVKL------------HGGIDILVSNAAV 102 Query: 124 TQE-SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + T +++N +P MT + M K ++V +S Sbjct: 103 NPFFGSIMDVTEEVWDKTLDINVKAPALMTKAVVPEMEKR-----------GGGSVVIVS 151 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTD--MIQNL 240 SI + PG S Y+ SK AL T+ LA E+ PRNIR ++PGL+K + M+ + Sbjct: 152 SI--AAFSPSPGFSPYNVSKTALLGLTKTLAIELAPRNIRVNCLAPGLIKTSFSRML-WM 208 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E +E ++ T+ P + A V L S A Sbjct: 209 DKEKEESMKETLRIRRLGEPEDCAGIVSFLCSEDA 243 >5OVL-A nrPDB Length = 300 Score = 171 bits (433), Expect = 3e-43, Method: Composition-based stats. Identities = 46/268 (17%), Positives = 91/268 (33%), Gaps = 57/268 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG RGIG AI ++L G + + + + Sbjct: 72 LVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQCD----------------- 114 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 D + + + + E + V +L+ AG+++++ Sbjct: 115 -----------------VTDSAAVDRAFKEV---------EEHQGPVEVLVANAGISKDA 148 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 +R T + ++++N N + M + + I+ I S+ S Sbjct: 149 FLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKRF-----------GRIIFIGSV--S 195 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G + + Y+A+KA L ++ E+ + ++PG + T+M + L + Sbjct: 196 GMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYID-TEMTRALDERIQAG 254 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 I A E+A V L S A Sbjct: 255 ALDFIPAKRVGTAEEVAGAVSFLASEDA 282 >2AE2-A nrPDB Length = 260 Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 66/274 (24%), Positives = 106/274 (38%), Gaps = 50/274 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG +RGIG I ++L G S + +L L+ R ++ Sbjct: 12 ALVTGGSRGIGYGIVEELASLGASVYTCSRNQ----------KELNDCLTQWRSKGFKVE 61 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 S + +R L + F +N+L+N AG+ Sbjct: 62 ----------ASVCDLSSRSERQELMNTVANHF-----------HGKLNILVNNAGIVIY 100 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T IM++NF + ++ + ++ S+R +V ISS+ Sbjct: 101 KEAKDYTVEDYSLIMSINFEAAYHLSVLAHPFLKASER-----------GNVVFISSV-- 147 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT--DMIQNLPVEA 244 SG + VP +VY A+K A+ + T LA E NIR + PG++ + +M P E Sbjct: 148 SGALAVPYEAVYGATKGAMDQLTRCLAFEWAKDNIRVNGVGPGVIATSLVEMTIQDP-EQ 206 Query: 245 KEMLERTI---GASGTSAPAEIAEEVWSLYSRTA 275 KE L + I P E+A V L A Sbjct: 207 KENLNKLIDRCALRRMGEPKELAAMVAFLCFPAA 240 >2ZAT-A nrPDB Length = 260 Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 61/274 (22%), Positives = 103/274 (37%), Gaps = 47/274 (17%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 VA+VT +T GIG AI ++L Q G ++ +E+++RT ++ Sbjct: 14 NKVALVTASTDGIGLAIARRLAQDGAHVVVSSRKQENVDRTVATLQGEGLSVTGT----- 68 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + +DR L L V++L++ A + Sbjct: 69 ---------------VCHVGKAEDRERLVAMAVNL------------HGGVDILVSNAAV 101 Query: 124 TQE-SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + T I++VN + V MT + M K +++ +S Sbjct: 102 NPFFGNIIDATEEVWDKILHVNVKATVLMTKAVVPEMEKR-----------GGGSVLIVS 150 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM-IQNLP 241 S+ P Y+ SK AL T+ LA E+ PRNIR ++PGL+K + + Sbjct: 151 SV--GAYHPFPNLGPYNVSKTALLGLTKNLAVELAPRNIRVNCLAPGLIKTNFSQVLWMD 208 Query: 242 VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 KE ++ ++ P + A V L S A Sbjct: 209 KARKEYMKESLRIRRLGNPEDCAGIVSFLCSEDA 242 >1AE1-A nrPDB Length = 273 Score = 168 bits (425), Expect = 2e-42, Method: Composition-based stats. Identities = 61/275 (22%), Positives = 110/275 (40%), Gaps = 51/275 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG ++GIG AI ++L G ++ ++ L R+ + ++ Sbjct: 24 ALVTGGSKGIGYAIVEELAGLGARVYTCSRNEKELDE----------CLEIWREKGLNVE 73 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 S + +R L Q + +FD +N+L+N AG+ Sbjct: 74 ----------GSVCDLLSRTERDKLMQTVAHVFD-----------GKLNILVNNAGVVIH 112 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T IM NF + ++ I + SQ ++ +SSI Sbjct: 113 KEAKDFTEKDYNIIMGTNFEAAYHLSQIAYPLLKASQ-----------NGNVIFLSSI-- 159 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL---PVE 243 +G +P S+YSASK A+++ T+ LA E NIR +++PG++ T +++ Sbjct: 160 AGFSALPSVSLYSASKGAINQMTKSLACEWAKDNIRVNSVAPGVI-LTPLVETAIKKNPH 218 Query: 244 AKEMLERTI---GASGTSAPAEIAEEVWSLYSRTA 275 KE ++ I P E++ + L A Sbjct: 219 QKEEIDNFIVKTPMGRAGKPQEVSALIAFLCFPAA 253 >4DBZ-A nrPDB Length = 281 Score = 168 bits (425), Expect = 3e-42, Method: Composition-based stats. Identities = 59/282 (20%), Positives = 100/282 (35%), Gaps = 53/282 (18%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 VA+VTGAT GIG I ++L ++GL + +E + T + + Sbjct: 26 SEVALVTGATSGIGLEIARRLGKEGLRVFVCARGEEGLRTTLKELREAG----------- 74 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 E+ + P ++ + + ER V++L+N AG Sbjct: 75 ------------VEADGRTCDVRSVPEIEALVAAVV---------ERYGPVDVLVNNAGR 113 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + D++ N +T +K + IVNI+S Sbjct: 114 PGGGATAELADELWLDVVETNLTGVFRVTKQVLKA---------GGMLERGTGRIVNIAS 164 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG---------- 233 GK + + YSASK + FT+ L E+ I + PG V+ Sbjct: 165 --TGGKQGLVHAAPYSASKHGVVGFTKALGLELARTGITVNAVCPGFVETPMAASVREHY 222 Query: 234 TDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +D+ + EA + + + P+E+AE V L A Sbjct: 223 SDIWEVSTEEAFDRITARVPIGRYVQPSEVAEMVAYLIGPGA 264 >4RZI-B nrPDB Length = 240 Score = 167 bits (423), Expect = 4e-42, Method: Composition-based stats. Identities = 56/271 (20%), Positives = 94/271 (34%), Gaps = 56/271 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V +VTG RGIG AI + L + G + A+ Sbjct: 9 KVIVVTGGNRGIGAAIVKLLQEMGAKVAFTDLATDGGNTEAL------------------ 50 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + D + + + D ++ AG+T Sbjct: 51 ---------------GVVANVTDLESMTAAAAEITDKLGPVYG---------VVANAGIT 86 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++ + T + ++NVN I+ M + + +IV ISSI Sbjct: 87 KDNFFPKLTPADWDAVLNVNLKGVAYSIKPFIEGMYERKA-----------GSIVAISSI 135 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 SG+ G + YSA+KA + + LA E +R ++PG + T+M + + Sbjct: 136 --SGERGNVGQTNYSATKAGVIGMMKSLAREGARYGVRANAVAPGFID-TEMTLAIREDI 192 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +E + + I P EIA V L S A Sbjct: 193 REKITKEIPFRRFGKPEEIAWAVAFLLSPVA 223 >1GEG-A nrPDB Length = 256 Score = 167 bits (423), Expect = 4e-42, Method: Composition-based stats. Identities = 55/284 (19%), Positives = 97/284 (34%), Gaps = 56/284 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VA+VTGA +GIGKAI +L + G + I + + A + Q Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGG--------- 51 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 +D D + ++ + ++++N AG Sbjct: 52 -----HAVAVKVDVSDRDQVFAAVEQA------------------RKTLGGFDVIVNNAG 88 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + + T + + N+N + ++ K + I+N Sbjct: 89 VAPSTPIESITPEIVDKVYNINVKGVIWGIQAAVEAFKK----------EGHGGKIINAC 138 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S +G + P +VYS+SK A+ T+ A ++ P I PG+VK T M + Sbjct: 139 S--QAGHVGNPELAVYSSSKFAVRGLTQTAARDLAPLGITVNGYCPGIVK-TPMWAEIDR 195 Query: 243 EAKEM-----------LERTIGASGTSAPAEIAEEVWSLYSRTA 275 + E + I S P ++A V L S + Sbjct: 196 QVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVAACVSYLASPDS 239 >1UZM-A nrPDB Length = 247 Score = 166 bits (420), Expect = 8e-42, Method: Composition-based stats. Identities = 53/268 (19%), Positives = 98/268 (36%), Gaps = 57/268 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG RGIG AI Q+L G + + + Sbjct: 19 LVTGGNRGIGLAIAQRLAADGHKVAVTHRGSGAPK------------------------- 53 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 + +D D ++ + E + V +L++ AGL+ ++ Sbjct: 54 GLFGVEVDVTDSDAVDRA------------------FTAVEEHQGPVEVLVSNAGLSADA 95 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 +R T + + ++N N + + M +++ ++ I S+ S Sbjct: 96 FLMRMTEEKFEKVINANLTGAFRVAQRASRSMQRNKF-----------GRMIFIGSV--S 142 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G + + Y+ASKA + +A E+ N+ ++PG + TDM + L ++ Sbjct: 143 GLWGIGNQANYAASKAGVIGMARSIARELSKANVTANVVAPGYID-TDMTRALDERIQQG 201 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I A PAE+A V L S A Sbjct: 202 ALQFIPAKRVGTPAEVAGVVSFLASEDA 229 >4IIV-A nrPDB Length = 267 Score = 166 bits (420), Expect = 8e-42, Method: Composition-based stats. Identities = 54/273 (19%), Positives = 95/273 (34%), Gaps = 45/273 (16%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 +VTGA++GIG+AI ++L G + + + + ++ G Sbjct: 25 MSRSVLVTGASKGIGRAIARQLAADGFNIGVHYHRDAAGAQETLNAIVANGG-------- 76 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 +R ++ W +++ AG Sbjct: 77 --------------NGRLLSFDVANREQCREVLEHEIAQHGAWYG---------VVSNAG 113 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + +++ + +++ N S + CI M+ G I+ +S Sbjct: 114 IARDAAFPALSNDDWDAVIHTNLDSFYNVIQPCIMPMI----------GARQGGRIITLS 163 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S+ SG M G YSA+KA + T+ LA E+ R I I+PGL+ T MI+ + Sbjct: 164 SV--SGVMGNRGQVNYSAAKAGIIGATKALAIELAKRKITVNCIAPGLID-TGMIE-MEE 219 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 A + I E+A L S A Sbjct: 220 SALKEAMSMIPMKRMGQAEEVAGLASYLMSDIA 252 >5OVJ-A nrPDB Length = 256 Score = 166 bits (420), Expect = 8e-42, Method: Composition-based stats. Identities = 46/268 (17%), Positives = 91/268 (33%), Gaps = 57/268 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG RGIG AI ++L G + + + + Sbjct: 28 LVTGGNRGIGLAIARRLAADGHKVAVTHRGSGAPDDLFGVQCD----------------- 70 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 D + + + + E + V +L+ AG+++++ Sbjct: 71 -----------------VTDSAAVDRAFKEV---------EEHQGPVEVLVANAGISKDA 104 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 +R T + ++++N N + M + + I+ I S+ S Sbjct: 105 FLMRMTEERFEEVINTNLTGAFRCAQRASRTMQRKRF-----------GRIIFIGSV--S 151 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G + + Y+A+KA L ++ E+ + ++PG + T+M + L + Sbjct: 152 GMWGIGNQANYAAAKAGLIGMARSISRELAKAGVTANVVAPGYID-TEMTRALDERIQAG 210 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 I A E+A V L S A Sbjct: 211 ALDFIPAKRVGTAEEVAGAVSFLASEDA 238 >1GEE-A nrPDB Length = 261 Score = 165 bits (416), Expect = 3e-41, Method: Composition-based stats. Identities = 52/272 (19%), Positives = 100/272 (36%), Gaps = 44/272 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V ++TG++ G+GK++ + + ++ +KE + ++ + G + + + Sbjct: 8 KVVVITGSSTGLGKSMAIRFATEKAKVVVNYRSKEDEANSVLEEIKKVGGEAIAVKGDVT 67 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 ++ + + K ++++IN AGL Sbjct: 68 VE----------------------SDVINLVQSAIKEFGK---------LDVMINNAGLE 96 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 S + S +++ N + IKY +++ + T++N+SS+ Sbjct: 97 NPVSSHEMSLSDWNKVIDTNLTGAFLGSREAIKYFVEND----------IKGTVINMSSV 146 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL-PVE 243 K+ P Y+ASK + TE LA E P+ IR I PG + + E Sbjct: 147 HE--KIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAINTPINAEKFADPE 204 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + +E I P EIA L S A Sbjct: 205 QRADVESMIPMGYIGEPEEIAAVAAWLASSEA 236 >5B1Y-A nrPDB Length = 270 Score = 163 bits (413), Expect = 5e-41, Method: Composition-based stats. Identities = 63/270 (23%), Positives = 113/270 (41%), Gaps = 47/270 (17%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESI-ERTAIDRGQLQSGLSYQRQCAIAI 65 A+VTG +RGIG+A + ++G S +I ++ + E+TA + +L S +Y Sbjct: 26 ALVTGGSRGIGRATVLRFAREGWSVVIAYKSRADLAEKTAEEARRLGSPEAYT------- 78 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 +D D + R E ++N+L+N AG+ Q Sbjct: 79 ------VRVDVGDPDSVTEMSSR------------------VGELIPHLNVLVNAAGVLQ 114 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 T+ S+ ++ + VN +T + + + K++ +IVN++SI Sbjct: 115 LGGIEETSISEWEETLRVNLTGVYLVTKLLLPLLRKAK-----------WASIVNVASIA 163 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVE 243 V G + YSASKA + T+ LA ++ IR ++P V+ TDM ++ E Sbjct: 164 GETGNVVAGVA-YSASKAGVIGLTKRLAVQLAGYGIRVNAVAPSFVE-TDMTRSFLDTPE 221 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 +E + P ++AE + L Sbjct: 222 KRERIASLHPLKIILKPEDVAEAILFLADP 251 >2GDZ-A nrPDB Length = 267 Score = 163 bits (411), Expect = 1e-40, Method: Composition-based stats. Identities = 65/282 (23%), Positives = 110/282 (39%), Gaps = 59/282 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTGA +GIG+A + L KG ++ E+ QC A Sbjct: 8 KVALVTGAAQGIGRAFAEALLLKGAKVALVDWNLEA-----------------GVQCKAA 50 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + P + D D+ L+ + + D + +++L+N AG+ Sbjct: 51 LHEQFEPQKTLFIQCD----VADQQQLRDTFRKVVDHFGR---------LDILVNNAGVN 97 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + +N +S ++ T + + YM K I+N+SS+ Sbjct: 98 N--------EKNWEKTLQINLVSVISGTYLGLDYMSKQN--------GGEGGIIINMSSL 141 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEV--LAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 +G M V VY ASK + FT LAA + +R I PG V T +++++ Sbjct: 142 --AGLMPVAQQPVYCASKHGIVGFTRSAALAANLMNSGVRLNAICPGFVN-TAILESIEK 198 Query: 243 EA--------KEMLERTIGASGTSAPAEIAEEVWSLYSRTAL 276 E K+ ++ I G P IA + +L AL Sbjct: 199 EENMGQYIEYKDHIKDMIKYYGILDPPLIANGLITLIEDDAL 240 >3OEC-A nrPDB Length = 317 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 60/289 (20%), Positives = 109/289 (37%), Gaps = 54/289 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA +TGA RG G+ +L Q G + AID + Q L Y + Sbjct: 47 KVAFITGAARGQGRTHAVRLAQDGADIV------------AIDLCRQQPNLDYAQGS--P 92 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + K+ ++ + I D L + + + ++ ++++L++ G++ Sbjct: 93 EELKETVRLVEEQGRRIIARQADVRDLASLQAVVDEALAEF------GHIDILVSNVGIS 146 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + V T Q DI+ N + + M++ + +++ +SS Sbjct: 147 NQGEVVSLTDQQWSDILQTNLIGAWHACRAVLPSMIE----------RGQGGSVIFVSST 196 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN----- 239 + G PG S Y+ASK + LA E+ NIR +++PG V T+M N Sbjct: 197 V--GLRGAPGQSHYAASKHGVQGLMLSLANEVGRHNIRVNSVNPGAVN-TEMALNEKLLK 253 Query: 240 ---------LPVEAKEMLER----TIGASGTSAPAEIAEEVWSLYSRTA 275 +A E+ + I P +++ V L S A Sbjct: 254 MFLPHLENPTREDAAELFSQLTLLPIP---WVEPEDVSNAVAWLASDEA 299 >5ITV-A nrPDB Length = 255 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 45/278 (16%), Positives = 87/278 (31%), Gaps = 54/278 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 ++TG GIG A Q + + ++ + E Sbjct: 6 TDKTVLITGGASGIGYAAVQAFLGQQANVVVADIDEAQGEAMVRKENN------------ 53 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 L + D + + ++ T +++LIN AG Sbjct: 54 ---------DRLHFVQTDITDEAACQHAVESAVHT-------------FGGLDVLINNAG 91 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + + S ++ VN M+ +K+M+ + + I+N Sbjct: 92 IEIVAPIHEMELSDWNKVLQVNLTGMFLMSKHALKHMLAA-----------GKGNIINTC 140 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT-------D 235 S+ G + P Y+ASK + + T+ +A + IR + PG++ + Sbjct: 141 SV--GGLVAWPDIPAYNASKGGVLQLTKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLE 198 Query: 236 MIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 + E K+ + P EIA + L S Sbjct: 199 NNEGTLEEIKKEKAKVNPLLRLGKPEEIANVMLFLASD 236 >3WYE-A nrPDB Length = 256 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 58/284 (20%), Positives = 97/284 (34%), Gaps = 56/284 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VA+VTGA +GIGKAI +L + G + I + + A + Q A Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGG-----HAVA 55 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 + +D ++Q TL ++++N AG Sbjct: 56 VKVDVSDRDQVF--------------AAVEQARKTL-------------GGFDVIVNNAG 88 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + Q + T ++ I +VN S ++ K ++ S Sbjct: 89 IAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAAVEAFKKEGHGGKIINAASIAA------ 142 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 P S YS +K A+ T+ A ++ P I PG+V GT M + + Sbjct: 143 ------IQGFPILSAYSTTKFAVRGLTQTAARDLAPLGITVNGYCPGIV-GTGMWEQIDA 195 Query: 243 EAKEMLERTIG-----------ASGTSAPAEIAEEVWSLYSRTA 275 E ++ + IG S P ++A V L S + Sbjct: 196 ELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASPDS 239 >2X9N-A nrPDB Length = 288 Score = 161 bits (406), Expect = 3e-40, Method: Composition-based stats. Identities = 61/273 (22%), Positives = 113/273 (41%), Gaps = 29/273 (10%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 P A+VTGA + IG+AI KL Q G +I ++ E+ A + + +S + Q + Sbjct: 24 PAAVVTGAAKRIGRAIAVKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVVCQADL 83 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + + F C+ NN +Y L+ G Sbjct: 84 T---------------NSNVLPASCEEIINSCFRAFGRCDVLVNNASAFYPTPLVQ--GD 126 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 +++ + +T +Q+ +++ N ++P +T + + + + P S+ +IVN+ Sbjct: 127 HEDNSNGKTVETQVAELIGTNAIAPFLLT---MSFAQRQKGTNPNC--TSSNLSIVNLCD 181 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 + S+Y+ K AL T+ A E+ P IR ++PG+ + + + E Sbjct: 182 AMVD--QPCMAFSLYNMGKHALVGLTQSAALELAPYGIRVNGVAPGV---SLLPVAMGEE 236 Query: 244 AKEMLERTIGASGTSAPAE-IAEEVWSLYSRTA 275 K+ R + A AE IA+ V L S +A Sbjct: 237 EKDKWRRKVPLGRREASAEQIADAVIFLVSGSA 269 >3WTC-A nrPDB Length = 262 Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats. Identities = 63/282 (22%), Positives = 104/282 (36%), Gaps = 56/282 (19%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 +A VTGA +GIGKAI +L + G I+L ++++ TA + L +R A+ Sbjct: 9 KIAAVTGAAQGIGKAIALRLAKDGADVILLDVKQDTLAETAKEVEALG-----RRAVALT 63 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D + R L TL +++++N AG+ Sbjct: 64 ADISNRDQF--------------RSTLADAAKTL-------------GGLDIMVNNAGIC 96 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 Q + ++I+ I ++N + + + + I+N SI Sbjct: 97 QVKPILDIEPAEIEKIFSINVQGVLWGMQAAATLFKE----------KGTKGKIINACSI 146 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 +G P YSA+K A+ T+ A E+ I + PG+V GTDM + Sbjct: 147 --AGHEGYPLLGAYSATKFAVRALTQSAAKELASSGITVNSYCPGIV-GTDMWVTIDKRM 203 Query: 245 KEMLERTIGA-----------SGTSAPAEIAEEVWSLYSRTA 275 E+ IGA ++A V L S A Sbjct: 204 AEITGTEIGATYKKYVEGIALGRVETADDVAGFVAYLSSSDA 245 >3A28-C nrPDB Length = 258 Score = 160 bits (403), Expect = 8e-40, Method: Composition-based stats. Identities = 58/284 (20%), Positives = 97/284 (34%), Gaps = 54/284 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VA+VTG +GIG+ I +KL G + ++ E A + +L Sbjct: 1 MSKVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQ--EEQAAETIKLIE--------- 49 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 A D K LD + D E+ ++L+N AG Sbjct: 50 -AADQKAVFVGLDVTDKANFDSAIDEAA------------------EKLGGFDVLVNNAG 90 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + Q + T ++ I +VN S + + + ++ S Sbjct: 91 IAQIKPLLEVTEEDLKQIYSVNVFSVFFGIQAASRKFDELGVKGKIINAASIAA------ 144 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 P S YS +K A+ T+ A E+ P+ +PG+V GT M + + Sbjct: 145 ------IQGFPILSAYSTTKFAVRGLTQAAAQELAPKGHTVNAYAPGIV-GTGMWEQIDA 197 Query: 243 EAKEMLERTIG-----------ASGTSAPAEIAEEVWSLYSRTA 275 E ++ + IG S P ++A V L S + Sbjct: 198 ELSKINGKPIGENFKEYSSSIALGRPSVPEDVAGLVSFLASENS 241 >3U5T-A nrPDB Length = 267 Score = 160 bits (403), Expect = 9e-40, Method: Composition-based stats. Identities = 53/274 (19%), Positives = 97/274 (35%), Gaps = 46/274 (16%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VAIVTGA+RGIG AI +L G + +I + K + + + G + Q Sbjct: 24 METNKVAIVTGASRGIGAAIAARLASDGFTVVINYAGKAAAAEEVAGKIEAAGGKALTAQ 83 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 + D +++ ++T E V++L+N Sbjct: 84 ADV----------------------SDPAAVRRLFATA---------EEAFGGVDVLVNN 112 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+ + T + ++ VN + + I+N Sbjct: 113 AGIMPLTTIAETGDAVFDRVIAVNLKGTFNTLREAAQRLR-------------VGGRIIN 159 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 +S+ + P +Y+A+KA + T VL+ E+ R+I ++PG ++ Sbjct: 160 MST--SQVGLLHPSYGIYAAAKAGVEAMTHVLSKELRGRDITVNAVAPGPTATDLFLEGK 217 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRT 274 E ++ + P +IA V L Sbjct: 218 SDEVRDRFAKLAPLERLGTPQDIAGAVAFLAGPD 251 >6CI9-A nrPDB Length = 259 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 56/272 (20%), Positives = 97/272 (35%), Gaps = 51/272 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 AIVTG ++GIG+ I + G+ +I G ++ ++RT D + ++ R Sbjct: 12 AIVTGGSKGIGRGIAETFANAGVDVVITGRNQDDLDRTVADLSGTRGKVTAVRA------ 65 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 D + R + + S ++++ AG+ Sbjct: 66 -------------DVTDPEDARRTVAETVSRH-------------GGLDIVCANAGIFPS 99 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 T I+ ++ VNF V + ++ + S +V SSI Sbjct: 100 GRLEDLTPDDIEQVLGVNFKGTVYIVQAALQALTAS-----------GHGRVVVTSSITG 148 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 PG S Y ASKAA F A E+ P+ I + PG + M + L ++ Sbjct: 149 P-ITGYPGWSHYGASKAAQLGFLRTAAMELAPKKITINAVLPGNI----MTEGLDEMGQD 203 Query: 247 MLERT---IGASGTSAPAEIAEEVWSLYSRTA 275 L++ I A + A+I + A Sbjct: 204 YLDQMASAIPAGRLGSVADIGNAALFFATDEA 235 >2CFC-A nrPDB Length = 250 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 59/278 (21%), Positives = 103/278 (37%), Gaps = 50/278 (17%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VAIVTGA+ G G AI + +G L + E++E TA + + + Sbjct: 1 MSRVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADKVLRVRAD 60 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 +A + + E+ +++L+N AG Sbjct: 61 VADEGDV-------------------------------NAAIAATMEQFGAIDVLVNNAG 89 Query: 123 LT---QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 +T + + T Q +M VN + +M+ IV Sbjct: 90 ITGNSEAGVLHTTPVEQFDKVMAVNVRGIFLGCRAVLPHMLLQ-----------GAGVIV 138 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 NI+S+ + + PG S Y+ SK A+ + T+ +A + IRC + PG+++ T M Q Sbjct: 139 NIASV--ASLVAFPGRSAYTTSKGAVLQLTKSVAVDYAGSGIRCNAVCPGMIE-TPMTQW 195 Query: 240 --LPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E ++ + I A++A+ V L A Sbjct: 196 RLDQPELRDQVLARIPQKEIGTAAQVADAVMFLAGEDA 233 >3AUT-A nrPDB Length = 269 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 90/272 (33%), Gaps = 44/272 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V ++TG + G+G+A+ + Q+ +I E A + G + Q + Sbjct: 16 KVVVITGGSTGLGRAMAVRFGQEEAKVVINYYNNEEEALDAKKEVEEAGGQAIIVQGDVT 75 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + T ++++IN AG+ Sbjct: 76 KE----------------------EDVVNLVQTAIKEFGT---------LDVMINNAGVE 104 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 S + +++ N + IKY +++ + ++N+SS+ Sbjct: 105 NPVPSHELSLDNWNKVIDTNLTGAFLGSREAIKYFVEND----------IKGNVINMSSV 154 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL-PVE 243 + P Y+ASK + TE LA E P+ IR I PG + + Sbjct: 155 HE--MIPWPLFVHYAASKGGMKLMTETLALEYAPKGIRVNNIGPGAMNTPINAEKFADPV 212 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + +E I P E+A L S A Sbjct: 213 QRADVESMIPMGYIGKPEEVAAVAAFLASSQA 244 >1P33-A nrPDB Length = 289 Score = 156 bits (393), Expect = 1e-38, Method: Composition-based stats. Identities = 53/277 (19%), Positives = 103/277 (37%), Gaps = 16/277 (5%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQC 61 PVA+VTGA + +G +I + L +G + + + A + + Q Sbjct: 6 TAPVALVTGAAKRLGSSIAEALHAEGYTVCLHYHRSAADASTLAATLNARRPNSAITVQA 65 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN-C 120 ++ + + + + F L + C+ NN +Y L+ Sbjct: 66 DLSN--VATASFSETDGSVPVTLFSRCSALVDACYMHWGRCDVLVNNASSFYPTPLLRKD 123 Query: 121 AGLTQESLSVRTTAS-QIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 AG S+ + + D+ N ++P + + + +IV Sbjct: 124 AGEGGSSVGDKESLEVAAADLFGSNAIAPYFLIKA-----FAQRVADTRAEQRGTSYSIV 178 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 N+ + S + G ++Y+ +K AL T A E+ IR +SPGL + + + Sbjct: 179 NMVDAMTS--QPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL---SVLPDD 233 Query: 240 LPVEAKEMLERTIGAS-GTSAPAEIAEEVWSLYSRTA 275 +P +E R + S+ E+++ V L S A Sbjct: 234 MPFSVQEDYRRKVPLYQRNSSAEEVSDVVIFLCSPKA 270 >5OJG-A nrPDB Length = 260 Score = 155 bits (391), Expect = 2e-38, Method: Composition-based stats. Identities = 60/277 (21%), Positives = 98/277 (35%), Gaps = 51/277 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VAIVT AT+GIG AI ++L +G S +I +++++ Sbjct: 11 KVAIVTAATKGIGLAIAERLLDEGASVVIGSRNQKNVDEAIEYLKNKGLT---------- 60 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 K S D + D ++ +N+L+N G+ Sbjct: 61 ---KVAGIAGHIASTDDQKKLVD------------------FTLQKFGKINILVNNHGIN 99 Query: 125 QESL-SVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + + + VN + MT + ++ K + I N S Sbjct: 100 PAFGHILEVSDQVWDKLFEVNVKAGFQMTKLVHPHIAK----------EGGGAIIFNAS- 148 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--- 240 +S PG + Y +K L T LA + NIR I+PG++K T M Q L Sbjct: 149 --YSAYKSPPGIAAYGVTKTTLVGLTRALAMGLAKDNIRVNGIAPGVIK-TKMSQVLWDG 205 Query: 241 PVEAKEMLE--RTIGASGTSAPAEIAEEVWSLYSRTA 275 +A++ L + I P + A V L S + Sbjct: 206 GEDAEKELTDIQEIALGRLGVPDDCAGTVAYLASDDS 242 >1NFF-A nrPDB Length = 260 Score = 154 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 55/273 (20%), Positives = 91/273 (33%), Gaps = 54/273 (19%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VA+V+G RG+G + + + +G + E Sbjct: 6 TGKVALVSGGARGMGASHVRAMVAEGAKVVFGDILDE----------------------- 42 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 + K L + K T +++L+N AG Sbjct: 43 ---EGKAMAAELADAARYVHLDVTQPAQWKAAVDTAVTAF---------GGLHVLVNNAG 90 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + ++ Q I++VN +K M ++ R +I+NIS Sbjct: 91 ILNIGTIEDYALTEWQRILDVNLTGVFLGIRAVVKPMKEA-----------GRGSIINIS 139 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 SI G Y+A+K A+ T+ A E+ P IR +I PGLVK T M +P Sbjct: 140 SI--EGLAGTVACHGYTATKFAVRGLTKSTALELGPSGIRVNSIHPGLVK-TPMTDWVPE 196 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + P E++ V L S + Sbjct: 197 DIF-----QTALGRAAEPVEVSNLVVYLASDES 224 >4MOW-A nrPDB Length = 256 Score = 153 bits (387), Expect = 6e-38, Method: Composition-based stats. Identities = 59/273 (21%), Positives = 105/273 (38%), Gaps = 48/273 (17%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VAIVTGA++GIG AI + L +G + ++ ++ ++ + G R A+ Sbjct: 15 KVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGG----RAVAVG 70 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D K E +++L+N +G+ Sbjct: 71 GDVSKAADAQRIVDTAI---------------------------ETYGRLDVLVNNSGVY 103 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + T + + N + T +K++ +I+NISS+ Sbjct: 104 EFAPIEAITEEHYRRQFDTNVFGVLLTTQAAVKHL-------------GEGASIINISSV 150 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV--KGTDMIQNLPV 242 + S + P ++VYS +K A+ T VLA E+ PR IR I+PG++ +GT + Sbjct: 151 VTS--ITPPASAVYSGTKGAVDAITGVLALELGPRKIRVNAINPGMIVTEGTHSAGIIGS 208 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + P +IA L S A Sbjct: 209 DLEAQVLGQTPLGRLGEPNDIASVAVFLASDDA 241 >3V2H-A nrPDB Length = 281 Score = 153 bits (386), Expect = 7e-38, Method: Composition-based stats. Identities = 53/286 (18%), Positives = 91/286 (31%), Gaps = 54/286 (18%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 A++TG+T GIG AI + L + G + ++ G RT D S + A Sbjct: 24 MTKTAVITGSTSGIGLAIARTLAKAGANIVLNGFGAPDEIRTVTDEVAGLSSGTVLHHPA 83 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 + + + D ++L+N AG Sbjct: 84 D---------------------MTKPSEIADMMAMVADRF---------GGADILVNNAG 113 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + Q I+ VN S I M K I+NI+ Sbjct: 114 VQFVEKIEDFPVEQWDRIIAVNLSSSFHTIRGAIPPMKK-----------KGWGRIINIA 162 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S G + P S Y A+K + T+ +A E+ + +I PG V + + +P Sbjct: 163 SA--HGLVASPFKSAYVAAKHGIMGLTKTVALEVAESGVTVNSICPGYVLTPLVEKQIPD 220 Query: 243 EAK-----------EMLERTIGASGTSAPAEIAEEVWSLYSRTALE 277 +A+ E++ + ++A L A + Sbjct: 221 QARTRGITEEQVINEVMLKGQPTKKFITVEQVASLALYLAGDDAAQ 266 >2Q2Q-A nrPDB Length = 255 Score = 153 bits (386), Expect = 9e-38, Method: Composition-based stats. Identities = 50/280 (17%), Positives = 92/280 (32%), Gaps = 57/280 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A+VTG+T GIG I Q L + G + ++ G + I R +++ Sbjct: 5 KTALVTGSTSGIGLGIAQVLARAGANIVLNGFGDPAPALAEIARHGVKA----------- 53 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D ++ ++ V++L+N AG+ Sbjct: 54 --------------VHHPADLSDVAQIEALFALA---------EREFGGVDILVNNAGIQ 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + I+ +N + T + + M I+NI+S+ Sbjct: 91 HVAPVEQFPLESWDKIIALNLSAVFHGTRLALPGMRARN-----------WGRIINIASV 139 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 G + G + Y A+K + T+V+ E N+ C I PG V + + + A Sbjct: 140 --HGLVGSTGKAAYVAAKHGVVGLTKVVGLETATSNVTCNAICPGWVLTPLVQKQIDDRA 197 Query: 245 K----------EMLERTIGASGTSAPAEIAEEVWSLYSRT 274 ++L + P + E V L S Sbjct: 198 ANGGDPLQAQHDLLAEKQPSLAFVTPEHLGELVLFLCSEA 237 >2QHX-A nrPDB Length = 328 Score = 153 bits (385), Expect = 9e-38, Method: Composition-based stats. Identities = 50/277 (18%), Positives = 101/277 (36%), Gaps = 16/277 (5%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQC 61 +PVA+VTGA + +G++I + L +G + + + + + + Q Sbjct: 45 TVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQA 104 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 ++ D + + F L T + C+ NN +Y L+ Sbjct: 105 DLSNVATAPVSGADGSAP--VTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRND 162 Query: 122 --GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 G + D+ N ++P + + + +I+ Sbjct: 163 EDGHEPCVGDREAMETATADLFGSNAIAPYFLIKA-----FAHRVAGTPAKHRGTNYSII 217 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 N+ + + + G ++Y+ +K AL T A E+ P IR + PGL + ++ + Sbjct: 218 NMVDAMTN--QPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL---SVLVDD 272 Query: 240 LPVEAKEMLERTIGAS-GTSAPAEIAEEVWSLYSRTA 275 +P E + S+ AE+++ V L S A Sbjct: 273 MPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKA 309 >2NWQ-A nrPDB Length = 272 Score = 153 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 55/275 (20%), Positives = 108/275 (39%), Gaps = 47/275 (17%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 H +TGAT G G+A ++ + G S ++ G +E ++ A + Sbjct: 19 HMSSTLFITGATSGFGEACARRFAEAGWSLVLTGRREERLQALAGEL------------- 65 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 + + P LD + D L ++++TL LIN A Sbjct: 66 --SAKTRVLPLTLDVRDRAAMSAAVDN--LPEEFATLRG----------------LINNA 105 Query: 122 GLTQES-LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 GL + + +++ N + T + + P L A +IVN Sbjct: 106 GLALGTDPAQSCDLDDWDTMVDTNIKGLLYSTRLLL----------PRLIAHGAGASIVN 155 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 + S+ +GK PG+ VY +KA + +F+ L +++ +R + PGL + + Sbjct: 156 LGSV--AGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQGTGVRVTNLEPGLCESEFSLVRF 213 Query: 241 PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + ++T + P +IAE ++ + ++ A Sbjct: 214 GGD-QARYDKTYAGAHPIQPEDIAETIFWIMNQPA 247 >2BFA-A nrPDB Length = 288 Score = 152 bits (384), Expect = 1e-37, Method: Composition-based stats. Identities = 50/277 (18%), Positives = 101/277 (36%), Gaps = 16/277 (5%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQC 61 +PVA+VTGA + +G++I + L +G + + + + + + Q Sbjct: 5 TVPVALVTGAAKRLGRSIAEGLHAEGYAVCLHYHRSAAEANALSATLNARRPNSAITVQA 64 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 ++ D + + F L T + C+ NN +Y L+ Sbjct: 65 DLSNVATAPVSGADGSAP--VTLFTRCAELVAACYTHWGRCDVLVNNASSFYPTPLLRND 122 Query: 122 --GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 G + D+ N ++P + + + +I+ Sbjct: 123 EDGHEPCVGDREAMETATADLFGSNAIAPYFLIKA-----FAHRVAGTPAKHRGTNYSII 177 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 N+ + + + G ++Y+ +K AL T A E+ P IR + PGL + ++ + Sbjct: 178 NMVDAMTN--QPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL---SVLVDD 232 Query: 240 LPVEAKEMLERTIGAS-GTSAPAEIAEEVWSLYSRTA 275 +P E + S+ AE+++ V L S A Sbjct: 233 MPPAVWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKA 269 >5YSS-A nrPDB Length = 256 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 56/285 (19%), Positives = 86/285 (30%), Gaps = 57/285 (20%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 A+VTG+T GIG I Q L Q G + I+ G + A+ + G Sbjct: 4 TGKTALVTGSTSGIGLGIAQVLAQAGATLILNGFGDVDAAKDAVAQYGKTPGYH------ 57 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 D D Y V++LIN AG Sbjct: 58 -GADLSDEAQIADMMRYA---------------------------ESEFGGVDILINNAG 89 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + S + I+ +N S T + + M I+NI+ Sbjct: 90 IQHVSPIETFPVDKWNAIIAINLSSVFHTTRLALPGMRARN-----------WGRIINIA 138 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S+ G + S Y A+K + T+ +A E I C + PG V + Q + Sbjct: 139 SV--HGLVASKEKSAYVAAKHGVVGLTKTIALETAQTEITCNALCPGWVLTPLVQQQIDK 196 Query: 243 EAKEM----------LERTIGASGTSAPAEIAEEVWSLYSRTALE 277 E L + P ++ L S A + Sbjct: 197 RIAEGAEPEAARDALLAEKQPSREFVTPEQLGNLALFLCSDGAAQ 241 >3V2G-A nrPDB Length = 271 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 66/270 (24%), Positives = 101/270 (37%), Gaps = 47/270 (17%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A VTG +RGIG AI ++L +G + + + + + G R AI Sbjct: 32 KTAFVTGGSRGIGAAIAKRLALEGAAVALTYVNAAERAQAVVSEIEQAGG----RAVAIR 87 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D + D ++Q E +++L+N AG+ Sbjct: 88 ADNR------------------DAEAIEQAIRETV---------EALGGLDILVNSAGIW 120 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + TT + ++M VNF +P +++ I+ I S Sbjct: 121 HSAPLEETTVADFDEVMAVNFRAPFVAIRSASRHL-------------GDGGRIITIGSN 167 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 L + PG S+YSASKAAL+ T+ LA ++ PR I + PG TDM A Sbjct: 168 LAE-LVPWPGISLYSASKAALAGLTKGLARDLGPRGITVNIVHPGSTD-TDMNPADGDHA 225 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRT 274 + ER I P +IA V L Sbjct: 226 EAQRER-IATGSYGEPQDIAGLVAWLAGPQ 254 >5T5Q-A nrPDB Length = 247 Score = 150 bits (379), Expect = 5e-37, Method: Composition-based stats. Identities = 47/268 (17%), Positives = 93/268 (34%), Gaps = 50/268 (18%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++TGA GIG+AI + G + ++ +E ++ A G + + + + A D Sbjct: 13 VLTGANGGIGRAIAELFHASGANLVLTDLDREGLDAFAASLGSPERIATIKADASSADDA 72 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 +K ER ++ L+ AG+ Q Sbjct: 73 EKT---------------------------------VALAMERFGGIDFLVPSAGIYQAK 99 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 + + +++N + + + + +IV ++S+ + Sbjct: 100 PFAEMSDADWHRTISINLDGVFYLCKRALPALKEDS-------------SIVTLASL--A 144 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 + Y A+K A+ T L+ E+ P+ R +SPG+++ T M L + Sbjct: 145 AYRGAYVNAHYGATKGAMVSMTRALSRELAPKT-RVNGVSPGIIE-TPMTSELLKTRMDE 202 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 P+EIA + L S A Sbjct: 203 TMTQTPLKRLGKPSEIASVIAFLCSPAA 230 >4Z9Y-A nrPDB Length = 253 Score = 150 bits (379), Expect = 5e-37, Method: Composition-based stats. Identities = 53/271 (19%), Positives = 97/271 (35%), Gaps = 51/271 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA++TG G+G+ + L Q G + G++ Sbjct: 11 KVALITGCDTGLGQGMAIGLAQAGCDIV---------------------GVNIVEPKDTI 49 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + D +++ + +V++L+N AG+ Sbjct: 50 EKVTALGRRFLSLTADMSNVSGHAELVEKAVAE-------------FGHVDILVNNAGII 96 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + ++ + D+MN+N S M+ + +K Q I+NI+S+ Sbjct: 97 RREDAIEFSEKNWDDVMNLNIKSVFFMSQTVARQFIK----------QGKGGKIINIASM 146 Query: 185 L-HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--P 241 L G ++VP Y+ASK+A+ T ++A E I I+PG + T+ Q L Sbjct: 147 LSFQGGIRVPS---YTASKSAVMGVTRLMANEWAKHGINVNAIAPGYMA-TNNTQQLRAD 202 Query: 242 VEAKEMLERTIGASGTSAPAEIAEEVWSLYS 272 E + + I A P ++ L S Sbjct: 203 EERSKEILDRIPAGRWGLPQDLMGPSVFLAS 233 >4FC7-A nrPDB Length = 277 Score = 150 bits (379), Expect = 6e-37, Method: Composition-based stats. Identities = 54/273 (19%), Positives = 97/273 (35%), Gaps = 46/273 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA +TG GIG I + + G +I + L L+ R+ A A Sbjct: 28 KVAFITGGGSGIGFRIAEIFMRHGCHTVIASRS-------------LPRVLTAARKLAGA 74 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + P +D + + D+ + +++LINCA Sbjct: 75 TGRRCLPLSMDVRAPPAVMAAVDQA------------------LKEFGRIDILINCAAGN 116 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + + + +M+++ ++ + + + IVNI++ Sbjct: 117 FLCPAGALSFNAFKTVMDIDTSGTFNVSRVLYEKFFRDH-----------GGVIVNITAT 165 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PV 242 L G ++KAA+ T LA E P+NIR +++PG + GT+ ++ L P Sbjct: 166 L--GNRGQALQVHAGSAKAAVDAMTRHLAVEWGPQNIRVNSLAPGPISGTEGLRRLGGPQ 223 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + EIA V L S A Sbjct: 224 ASLSTKVTASPLQRLGNKTEIAHSVLYLASPLA 256 >1X1T-A nrPDB Length = 260 Score = 150 bits (377), Expect = 8e-37, Method: Composition-based stats. Identities = 57/288 (19%), Positives = 101/288 (35%), Gaps = 54/288 (18%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA+VTG+T GIG I L +G ++ G A + ++++GL+ Q Sbjct: 1 MLKGKVAVVTGSTSGIGLGIATALAAQGADIVLNGFGD------AAEIEKVRAGLAAQHG 54 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 + D D + + D + +++L+N Sbjct: 55 VKVLYD------GADLSKGEAVRGLVDNAV------------------RQMGRIDILVNN 90 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+ +L + I+ +N + T + +M K I+N Sbjct: 91 AGIQHTALIEDFPTEKWDAILALNLSAVFHGTAAALPHMKKQ-----------GFGRIIN 139 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 I+S G + S Y A+K + FT+V A E + I I PG V+ + + + Sbjct: 140 IASA--HGLVASANKSAYVAAKHGVVGFTKVTALETAGQGITANAICPGWVRTPLVEKQI 197 Query: 241 PV-----------EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALE 277 A+E+L + P ++ L S A + Sbjct: 198 SALAEKNGVDQETAARELLSEKQPSLQFVTPEQLGGTAVFLASDAAAQ 245 >1CYD-A nrPDB Length = 244 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 53/274 (19%), Positives = 97/274 (35%), Gaps = 55/274 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGA +GIG+ + L G + + T Sbjct: 10 ALVTGAGKGIGRDTVKALHASGAKVVAVTRTNS--------------------------- 42 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 D + K+ P ++ L D V+LL+N A L Sbjct: 43 -------------DLVSLAKECPGIEPVCVDLGDWDATEKALGGIGPVDLLVNNAALVIM 89 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T +VN S ++ + + M+ + +IVN+SS++ Sbjct: 90 QPFLEVTKEAFDRSFSVNLRSVFQVSQMVARDMIN----------RGVPGSIVNVSSMV- 138 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVEA 244 + P YS++K A++ T+ +A E+ P IR +++P +V TDM + + E Sbjct: 139 -AHVTFPNLITYSSTKGAMTMLTKAMAMELGPHKIRVNSVNPTVV-LTDMGKKVSADPEF 196 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 L+ + ++ + L S + T Sbjct: 197 ARKLKERHPLRKFAEVEDVVNSILFLLSDRSAST 230 >3D3W-A nrPDB Length = 244 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 56/269 (20%), Positives = 94/269 (34%), Gaps = 57/269 (21%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTGA +GIG+ Q L G + + T+ ++ Sbjct: 11 LVTGAGKGIGRGTVQALHATGARVVAVSRTQADLD------------------------- 45 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 ++ P ++ L D V+LL+N A + Sbjct: 46 ---------------SLVRECPGIEPVCVDLGDWEATERALGSVGPVDLLVNNAAVALLQ 90 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 + T VN + + ++ I + ++ + IVN+SS Sbjct: 91 PFLEVTKEAFDRSFEVNLRAVIQVSQIVARGLIA----------RGVPGAIVNVSS--QC 138 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL---PVEA 244 + V SVY ++K AL T+V+A E+ P IR ++P +V T M Q P +A Sbjct: 139 SQRAVTNHSVYCSTKGALDMLTKVMALELGPHKIRVNAVNPTVVM-TSMGQATWSDPHKA 197 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSR 273 K ML R I + + + L S Sbjct: 198 KTMLNR-IPLGKFAEVEHVVNAILFLLSD 225 >2B4Q-A nrPDB Length = 276 Score = 148 bits (373), Expect = 2e-36, Method: Composition-based stats. Identities = 53/268 (19%), Positives = 93/268 (34%), Gaps = 44/268 (16%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +A+VTG +RGIG+ I Q L + G I E+ TA + + Sbjct: 31 IALVTGGSRGIGQMIAQGLLEAGARVFICARDAEACADTATRLSAYGDCQAIPADLSSEA 90 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 ++ L E +++L+N AG + Sbjct: 91 GARRLAQAL---------------------------------GELSARLDILVNNAGTSW 117 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + S + +M +N S + + + +S ++NI S+ Sbjct: 118 GAALESYPVSGWEKVMQLNVTSVFSCIQQLLPLLRRSA-------SAENPARVINIGSVA 170 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVE 243 M + Y SKAAL + + +LA E+ +I I+PG + M +++ + Sbjct: 171 GISAMGEQAYA-YGPSKAALHQLSRMLAKELVGEHINVNVIAPGRF-PSRMTRHIANDPQ 228 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLY 271 A E +I P E+A SL Sbjct: 229 ALEADSASIPMGRWGRPEEMAALAISLA 256 >3W8F-A nrPDB Length = 260 Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats. Identities = 53/281 (18%), Positives = 94/281 (33%), Gaps = 56/281 (19%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG+T GIG A+ +L + G +I G + I + Sbjct: 7 AVVTGSTSGIGLAMATELAKAGADVVINGFGQPE---------------------DIERE 45 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 ++Y D + + E +++L+N AG+ Sbjct: 46 RSTLESKFGVKAYYLNADLSDAQATRDFIAKA---------AEALGGLDILVNNAGIQHT 96 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + + I+ +N + T + M K I+NI+S Sbjct: 97 APIEEFPVDKWNAIIALNLSAVFHGTAAALPIMQKQ-----------GWGRIINIASA-- 143 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ-------- 238 G + S Y A+K + T+V A E + I C I PG V+ T +++ Sbjct: 144 HGLVASVNKSAYVAAKHGVVGLTKVTALENAGKGITCNAICPGWVR-TPLVEKQIEAISQ 202 Query: 239 ----NLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 ++ A+E+L + P ++ L S A Sbjct: 203 QKGIDIEAAARELLAEKQPSLQFVTPEQLGGAAVFLSSAAA 243 >5U9P-A nrPDB Length = 265 Score = 148 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 48/268 (17%), Positives = 97/268 (36%), Gaps = 48/268 (17%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TG+ RGIG + + L + G + +I +E A Sbjct: 23 ALITGSGRGIGLTLARGLAEAGAAIVINDRNEEKAATLA-------------------RR 63 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 F+ D+ +D E+ + R + + R +++L+N AG+ + Sbjct: 64 FRDEGFAADHAVFDVAEHAQVRAAIDEF-------------EARVGAIDILVNNAGIQRR 110 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + +M VN + ++M+ I+NI S+ Sbjct: 111 APLDAFEPDDWHALMRVNLDGVFNVAQAVARHMIAR-----------GHGKIINICSVQS 159 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA-- 244 + P + Y+A+K A+ T+ + A+ I+ ++PG + T++ + L +A Sbjct: 160 E--LARPTIAPYAATKGAVRMLTKGMCADWARYGIQANGLAPGYFE-TELNRALVDDAAF 216 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYS 272 + L + A E+ L S Sbjct: 217 SDWLCKRTPAGRWGQVDELCGAAIFLAS 244 >4HP8-A nrPDB Length = 247 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 57/273 (20%), Positives = 99/273 (36%), Gaps = 58/273 (21%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGS--TKESIERTAIDRGQLQSGLSYQRQCAIA 64 A+VTGA G+G+AI L G + E+++ A D G + L Sbjct: 12 ALVTGANTGLGQAIAVGLAAAGAEVVCAARRAPDETLDIIAKDGGNASALL--------- 62 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 F D K ++ ++L+N AG+ Sbjct: 63 ------------------IDFADPLAAKDSFTDA--------------GFDILVNNAGII 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + SV + ++M+VN + T K ++ R +VNI+S+ Sbjct: 91 RRADSVEFSELDWDEVMDVNLKALFFTTQAFAKELLAKGR----------SGKVVNIASL 140 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 L Y+A+K ++ T++LA E + I I+PG ++ T+ + L +A Sbjct: 141 LS--FQGGIRVPSYTAAKHGVAGLTKLLANEWAAKGINVNAIAPGYIE-TNNTEALRADA 197 Query: 245 K--EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + I A +IA L S A Sbjct: 198 ARNKAILERIPAGRWGHSEDIAGAAVFLSSAAA 230 >1K2W-A nrPDB Length = 256 Score = 146 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 55/281 (19%), Positives = 95/281 (33%), Gaps = 57/281 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A++TG+ RGIG+A + ++G I E+ TA + G CAIA Sbjct: 6 KTALITGSARGIGRAFAEAYVREGARVAIADINLEAARATAAEIGPA--------ACAIA 57 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +D D+ + + + L D R +++L+N A L Sbjct: 58 LD------------------VTDQASIDRCVAELLD---------RWGSIDILVNNAALF 90 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + V T + +N + M + M+ R I+N++S Sbjct: 91 DLAPIVEITRESYDRLFAINVSGTLFMMQAVARAMIAGGR----------GGKIINMAS- 139 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT---------- 234 +G+ VY A+KAA+ T+ + I I+PG+V G Sbjct: 140 -QAGRRGEALVGVYCATKAAVISLTQSAGLNLIRHGINVNAIAPGVVDGEHWDGVDAKFA 198 Query: 235 DMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 D E K + + ++ L + A Sbjct: 199 DYENLPRGEKKRQVGAAVPFGRMGRAEDLTGMAIFLATPEA 239 >3RWB-A nrPDB Length = 247 Score = 144 bits (363), Expect = 4e-35, Method: Composition-based stats. Identities = 53/272 (19%), Positives = 94/272 (34%), Gaps = 49/272 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A+VTGA +GIGKAI +L G + I+ E + A G+ ++ Sbjct: 7 KTALVTGAAQGIGKAIAARLAADGATVIVSDINAEGAKAAAASIGKKARAIAA------- 59 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D +K ++ + +++L+N A + Sbjct: 60 -------------------DISDPGSVKALFAEI---------QALTGGIDILVNNASIV 91 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + I++VN +T M + + +++I+S Sbjct: 92 PFVAWDDVDLDHWRKIIDVNLTGTFIVTRAGTDQMRAAGKA----------GRVISIASN 141 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 P + Y A+K + FT LA E+ NI ++PGL++ +D ++ P Sbjct: 142 TF--FAGTPNMAAYVAAKGGVIGFTRALATELGKYNITANAVTPGLIE-SDGVKASPHNE 198 Query: 245 KEMLERTI-GASGTSAPAEIAEEVWSLYSRTA 275 + G P IA+ V L S A Sbjct: 199 AFGFVEMLQAMKGKGQPEHIADVVSFLASDDA 230 >2O23-A nrPDB Length = 265 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 63/278 (22%), Positives = 104/278 (37%), Gaps = 50/278 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA++TG G+G A ++L +G S ++L E A G Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQAKKLGN--------------- 58 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + + D K + L K+ V++ +NCAG+ Sbjct: 59 --------------NCVFAPADVTSEKDVQTALALAKGKF------GRVDVAVNCAGIAV 98 Query: 126 ESLSVRT------TASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 S + T Q +++VN M + + M ++ E R I+ Sbjct: 99 ASKTYNLKKGQTHTLEDFQRVLDVNLMGTFNVIRLVAGEMGQN-----EPDQGGQRGVII 153 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 N +S+ + G + YSASK + T +A ++ P IR TI+PGL GT ++ + Sbjct: 154 NTASV--AAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVMTIAPGLF-GTPLLTS 210 Query: 240 LPVEAKEMLERTIGA-SGTSAPAEIAEEVWSLYSRTAL 276 LP + L + S PAE A V ++ L Sbjct: 211 LPEKVCNFLASQVPFPSRLGDPAEYAHLVQAIIENPFL 248 >5IZ4-A nrPDB Length = 271 Score = 141 bits (355), Expect = 3e-34, Method: Composition-based stats. Identities = 62/274 (22%), Positives = 103/274 (37%), Gaps = 46/274 (16%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 PV ++TG+ GIG A + Q G S I G+ +S A L Q Sbjct: 14 TPVCVITGSASGIGAATALRFAQAGWSVAI-GNFDDSTRDAASTVEALCRDAGAQTLIFD 72 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 A D + ++ R ++ LINCAG Sbjct: 73 A------DVGKDADCRHAVDMVASR----------------------WQRIDALINCAGT 104 Query: 124 TQ---ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 T+ + + + + + VN + MT + + +S + ++VN Sbjct: 105 TRVIPHNAFDQIDDFEFERVYRVNLIGLYQMTRAAVPLLRESA-------SATRSTSVVN 157 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 +SS+ +G + Y+ASK A++ T LA + P IR ++PG+V +++ L Sbjct: 158 VSSL--AGLNGTGSSIAYAASKGAVNTLTLSLARNLAPH-IRVNALAPGMVDDGLLLRVL 214 Query: 241 PVEAKEMLERTI----GASGTSAPAEIAEEVWSL 270 A + + + S PAEIAE W L Sbjct: 215 DAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFL 248 >2EW8-A nrPDB Length = 249 Score = 139 bits (349), Expect = 1e-33, Method: Composition-based stats. Identities = 52/279 (18%), Positives = 92/279 (32%), Gaps = 62/279 (22%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 +A++TG GIG+AI ++ +G I AI Sbjct: 8 KLAVITGGANGIGRAIAERFAVEGADIAIADLVPAPEAEAAIRN---------------- 51 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + D +E F + + F C ++L+N AG+ Sbjct: 52 LGRRVLTVKCDVSQPGDVEAFGKQ------VISTFGRC------------DILVNNAGIY 93 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 T Q + +N S M + M ++ I+N++S Sbjct: 94 PLIPFDELTFEQWKKTFEINVDSGFLMAKAFVPGMKRN-----------GWGRIINLTST 142 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG--------TDM 236 + +K+ + Y ++KAA FT LA+++ I I+P LV+ + M Sbjct: 143 TY--WLKIEAYTHYISTKAANIGFTRALASDLGKDGITVNAIAPSLVRTATTEASALSAM 200 Query: 237 IQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 LP + + I P ++ L S A Sbjct: 201 FDVLP-----NMLQAIP--RLQVPLDLTGAAAFLASDDA 232 >1E3W-A nrPDB Length = 261 Score = 136 bits (343), Expect = 7e-33, Method: Composition-based stats. Identities = 59/278 (21%), Positives = 102/278 (36%), Gaps = 50/278 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA++TG G+G + ++L +G + ++L E A G Sbjct: 12 VAVITGGASGLGLSTAKRLVGQGATAVLLDVPNSEGETEAKKLG---------------- 55 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT- 124 + I + K+ + L E+ +++ +NCAG+ Sbjct: 56 -------------GNCIFAPANVTSEKEVQAALT------LAKEKFGRIDVAVNCAGIAV 96 Query: 125 -----QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 E + T Q ++NVN + + + M ++ E R I+ Sbjct: 97 AIKTYHEKKNQVHTLEDFQRVINVNLIGTFNVIRLVAGVMGQN-----EPDQGGQRGVII 151 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 N +S+ + G + YSASK + T +A ++ P IR TI+PGL T ++ Sbjct: 152 NTASV--AAFEGQVGQAAYSASKGGIVGMTLPIARDLAPIGIRVVTIAPGLFA-TPLLTT 208 Query: 240 LPVEAKEMLERTIGA-SGTSAPAEIAEEVWSLYSRTAL 276 LP + L + S PAE A V + L Sbjct: 209 LPDTVRNFLASQVPFPSRLGDPAEYAHLVQMVIENPFL 246 >4AVY-A nrPDB Length = 242 Score = 136 bits (343), Expect = 7e-33, Method: Composition-based stats. Identities = 44/270 (16%), Positives = 91/270 (33%), Gaps = 61/270 (22%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG + GIG AI + + G + LG + + Sbjct: 15 LVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHA------------------------ 50 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 P ++++ + D E +++L+N AG++++ Sbjct: 51 ------------------PRHPRIRREELDITDSQRLQRLFEALPRLDVLVNNAGISRD- 91 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 + + ++ +N + + + + + + +I+NI+S+ + Sbjct: 92 -REEYDLATFERVLRLNLSAAMLASQLARPLLAQR------------GGSILNIASMYST 138 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE- 246 YSASK A+ + T LA E IR I+PG + T + L + + Sbjct: 139 --FGSADRPAYSASKGAIVQLTRSLACEYAAERIRVNAIAPGWID-TPLGAGLKADVEAT 195 Query: 247 -MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + E+A L A Sbjct: 196 RRIMQRTPLARWGEAPEVASAAAFLCGPGA 225 >4E6P-A nrPDB Length = 259 Score = 136 bits (341), Expect = 1e-32, Method: Composition-based stats. Identities = 48/276 (17%), Positives = 93/276 (33%), Gaps = 57/276 (20%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TG+ RGIG+A + ++G + I E + A + G Sbjct: 11 ALITGSARGIGRAFAEAYVREGATVAIADIDIERARQAAAEIGPA--------------- 55 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + +D D I+ + E +++L+N A L Sbjct: 56 --AYAVQMDVTRQDSID------------------AAIAATVEHAGGLDILVNNAALFDL 95 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + V T + + +N + + M+ R I+N++S Sbjct: 96 APIVEITRESYEKLFAINVAGTLFTLQAAARQMIAQGR----------GGKIINMAS--Q 143 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT--DMIQNL---- 240 +G+ ++Y A+KAA+ T+ ++ I I+PG+V G D + L Sbjct: 144 AGRRGEALVAIYCATKAAVISLTQSAGLDLIKHRINVNAIAPGVVDGEHWDGVDALFARY 203 Query: 241 ----PVEAKEMLERTIGASGTSAPAEIAEEVWSLYS 272 E K ++ + ++ L S Sbjct: 204 ENRPRGEKKRLVGEAVPFGRMGTAEDLTGMAIFLAS 239 >3UVE-A nrPDB Length = 286 Score = 135 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 46/287 (16%), Positives = 87/287 (30%), Gaps = 45/287 (15%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA VTGA RG G++ +L Q+G I + K + + Sbjct: 12 KVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDLAETADLV 71 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + + D E+ +++++ AG+ Sbjct: 72 KGHNRRIVTAEVDVRDYDALKAAVDS----------------GVEQLGRLDIIVANAGIG 115 Query: 125 QESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 ++ +T+ +++++N + +M+ R +I+ SS Sbjct: 116 NGGDTLDKTSEEDWTEMIDINLAGVWKTVKAGVPHMIAGGR----------GGSIILTSS 165 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN---- 239 + G P T Y A+K + E+ IR ++ P VK T M+ N Sbjct: 166 V--GGLKAYPHTGHYVAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVK-TPMLHNEGTF 222 Query: 240 ---LPVEAKEMLERTIGASGT--------SAPAEIAEEVWSLYSRTA 275 P + P +I+ V S A Sbjct: 223 KMFRPDLENPGPDDMAPICQMFHTLPIPWVEPIDISNAVLFFASDEA 269 >2AG5-A nrPDB Length = 246 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 40/192 (20%), Positives = 69/192 (35%), Gaps = 17/192 (8%) Query: 89 PPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSP 148 P ++ + + +++L N AG + MN+N S Sbjct: 50 PGIQTRVLDVTKKKQIDQFANEVERLDVLFNVAGFVHHGTVLDCEEKDWDFSMNLNVRSM 109 Query: 149 VTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRF 208 M + M+ + I+N+SS+ S V VYS +KAA+ Sbjct: 110 YLMIKAFLPKMLAQK-----------SGNIINMSSVASS-VKGVVNRCVYSTTKAAVIGL 157 Query: 209 TEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL-----PVEAKEMLERTIGASGTSAPAEI 263 T+ +AA+ + IRC + PG V + + + P EA+ + + EI Sbjct: 158 TKSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEI 217 Query: 264 AEEVWSLYSRTA 275 A L S + Sbjct: 218 AMLCVYLASDES 229 >3T7C-A nrPDB Length = 299 Score = 133 bits (334), Expect = 8e-32, Method: Composition-based stats. Identities = 58/290 (20%), Positives = 101/290 (34%), Gaps = 55/290 (18%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA +TGA RG G++ L ++G I + K+ L+ + A Sbjct: 29 KVAFITGAARGQGRSHAITLAREGADIIAIDVCKQ--LDGVKLPMSTPDDLAETVRQVEA 86 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + +D +D ++ D + +++++ A L Sbjct: 87 LGRRIIASQVDVRDFDAMQAAVDDGV------------------TQLGRLDIVLANAALA 128 Query: 125 QESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 E + R +D+++VN + I ++M +R +IV SS Sbjct: 129 SEGTRLNRMDPKTWRDMIDVNLNGAWITARVAIPHIMAGKR----------GGSIVFTSS 178 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM------- 236 I G Y ASK L +A E+ PRNIR + P V T M Sbjct: 179 I--GGLRGAENIGNYIASKHGLHGLMRTMALELGPRNIRVNIVCPSSVA-TPMLLNEPTY 235 Query: 237 -----------IQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 +++ V +++M I PA+I+ + L S A Sbjct: 236 RMFRPDLENPTVEDFQVASRQMHVLPIP---YVEPADISNAILFLVSDDA 282 >1H5Q-A nrPDB Length = 265 Score = 133 bits (334), Expect = 8e-32, Method: Composition-based stats. Identities = 52/272 (19%), Positives = 91/272 (33%), Gaps = 37/272 (13%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 IVTG RGIG A + + G + ++ + G+ + QC + Sbjct: 14 NKTIIVTGGNRGIGLAFTRAVAAAGANVAVIYRSAADAVEVTEKVGKEFGVKTKAYQCDV 73 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + +T + ++ LI AG+ Sbjct: 74 S-------------------------------NTDIVTKTIQQIDADLGPISGLIANAGV 102 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + + T + +VN K ++ Q++ + S I+N SS Sbjct: 103 SVVKPATELTHEDFAFVYDVNVFGVFNTCRAVAKLWLQKQQKGSIVVTSSMSSQIINQSS 162 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 + Y++SKAA S + LAAE IR +SPG V TD ++ + Sbjct: 163 L-----NGSLTQVFYNSSKAACSNLVKGLAAEWASAGIRVNALSPGYVN-TDQTAHMDKK 216 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 ++ I + + P E+ + L S A Sbjct: 217 IRDHQASNIPLNRFAQPEEMTGQAILLLSDHA 248 >1O5I-A nrPDB Length = 249 Score = 132 bits (332), Expect = 1e-31, Method: Composition-based stats. Identities = 53/268 (19%), Positives = 93/268 (34%), Gaps = 60/268 (22%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +V A+RGIG+A+ L Q+G I +E ++R+ C + D Sbjct: 23 LVLAASRGIGRAVADVLSQEGAEVTICARNEELLKRSG----------HRYVVCDLRKDL 72 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 E+ V++L+ AG + Sbjct: 73 DLL-------------------------------------FEKVKEVDILVLNAGGPKAG 95 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 T ++ ++ S M+K R + + IV I+S Sbjct: 96 FFDELTNEDFKEAID----SLFLN-------MIKIVRNYLPAMKEKGWGRIVAITSFSVI 144 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 ++ TS +++ AL+ F + L+ E+ P I ++PG + + + L E K+ Sbjct: 145 SPIENLYTSN--SARMALTGFLKTLSFEVAPYGITVNCVAPGWTETERVKELLSEEKKKQ 202 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 +E I + P EIA V L S A Sbjct: 203 VESQIPMRRMAKPEEIASVVAFLCSEKA 230 >3OML-A nrPDB Length = 613 Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats. Identities = 49/269 (18%), Positives = 87/269 (32%), Gaps = 50/269 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA G+G+ ++G ++ G + QR I + Sbjct: 21 VAVVTGAGAGLGREYALLFAERGAKVVVNDLG-----------GTHSGDGASQRAADIVV 69 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D + Y+ + + + + V++L+N AG+ + Sbjct: 70 DEIRKAGGEAVADYNSV---------------IDGAKVIETAIKAFGRVDILVNNAGILR 114 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + V+T+ + +V+ T YM K I+ SS Sbjct: 115 DRSLVKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQN-----------YGRIIMTSS-- 161 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +SG G Y+A+K L +A E N+ C I P + M + + + Sbjct: 162 NSGIYGNFGQVNYTAAKMGLIGLANTVAIEGARNNVLCNVIVP--TAASRMTEGILPDIL 219 Query: 246 EMLERTIGASGTSAPAEIAEEVWSLYSRT 274 + P IA V L + Sbjct: 220 FNELK---------PKLIAPVVAYLCHES 239 >3UF0-A nrPDB Length = 273 Score = 128 bits (320), Expect = 4e-30, Method: Composition-based stats. Identities = 50/271 (18%), Positives = 89/271 (32%), Gaps = 50/271 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGA GIG+AI + G + G T Sbjct: 34 AVVTGAGSGIGRAIAHGYARAGAHVLAWGRTD---------------------------- 65 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + + + + + + L N V++L+N AG+ Sbjct: 66 ------GVKEVADEIADGGGSAEAVVADLADLEGAANVAEELAATRRVDVLVNNAGIIAR 119 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + + + + ++++ VN + ++ M+ IV I+S+L Sbjct: 120 APAEEVSLGRWREVLTVNLDAAWVLSRSFGTAMLA-----------HGSGRIVTIASMLS 168 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVEA 244 + Y+ASK A+ T LA+E R + ++PG V T L E Sbjct: 169 --FQGGRNVAAYAASKHAVVGLTRALASEWAGRGVGVNALAPGYV-VTANTAALRADDER 225 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I A + P ++ L S A Sbjct: 226 AAEITARIPAGRWATPEDMVGPAVFLASDAA 256 >1DOH-A nrPDB Length = 283 Score = 128 bits (320), Expect = 4e-30, Method: Composition-based stats. Identities = 48/283 (16%), Positives = 91/283 (32%), Gaps = 59/283 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTGA RGIG+ + +L ++G I+ + + + Sbjct: 30 KVALVTGAGRGIGREMAMELGRRGCKVIVNYANSTESAEEVVAAIKKNGS---------- 79 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D + ++ + + ++++ + +G+ Sbjct: 80 ---------------DAACVKANVGVVEDIVRMFEEAVKIF------GKLDIVCSNSGVV 118 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 T + + +N + K++ ++ + SI Sbjct: 119 SFGHVKDVTPEEFDRVFTINTRGQFFVAREAYKHL-------------EIGGRLILMGSI 165 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM-------- 236 K VP +VYS SK A+ F +A +M + I ++PG +K TDM Sbjct: 166 TGQAK-AVPKHAVYSGSKGAIETFARCMAIDMADKKITVNVVAPGGIK-TDMYHAVCREY 223 Query: 237 ---IQNLPVEAKEML--ERTIGASGTSAPAEIAEEVWSLYSRT 274 +NL E + + P +IA V L S Sbjct: 224 IPNGENLSNEEVDEYAAVQWSPLRRVGLPIDIARVVCFLASND 266 >3R3S-A nrPDB Length = 294 Score = 127 bits (319), Expect = 4e-30, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 90/273 (32%), Gaps = 51/273 (18%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG GIG+A ++G I E + + + G ++ + D Sbjct: 52 ALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDAQQVKALIEECG---RKAVLLPGD 108 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 F E +++L AG Sbjct: 109 LS---------------------------DESFARSLVHKAREALGGLDILALVAGKQTA 141 Query: 127 SLSVR-TTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 ++ T+ Q Q VN + +T I + K +I+ SSI Sbjct: 142 IPEIKDLTSEQFQQTFAVNVFALFWITQEAIPLLPK-------------GASIITTSSI- 187 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 P Y+A+KAA+ ++ LA ++ + IR ++PG + +Q + + Sbjct: 188 -QAYQPSPHLLDYAATKAAILNYSRGLAKQVAEKGIRVNIVAPGPIWT--ALQISGGQTQ 244 Query: 246 EML---ERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + + PAE+A L S+ + Sbjct: 245 DKIPQFGQQTPMKRAGQPAELAPVYVYLASQES 277 >2FWM-X nrPDB Length = 250 Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats. Identities = 54/277 (19%), Positives = 84/277 (30%), Gaps = 66/277 (23%) Query: 9 VTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFK 68 VTGA +GIG A + G F Sbjct: 12 VTGAGKGIGYATALAFVEAGAKV---------------------------------TGFD 38 Query: 69 KWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESL 128 + Y + D + Q L + ++ L+N AG+ + Sbjct: 39 QAFTQEQYPFATEVMDVADAAQVAQVCQRLLAETER---------LDALVNAAGILRMGA 89 Query: 129 SVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSG 188 + + + Q VN + + + + IV ++S + Sbjct: 90 TDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRRQR-----------GGAIVTVAS--DAA 136 Query: 189 KMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVEAKE 246 G S Y ASKAAL + E+ +RC +SPG TDM + L +A+E Sbjct: 137 HTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD-TDMQRTLWVSDDAEE 195 Query: 247 MLER--------TIGASGTSAPAEIAEEVWSLYSRTA 275 R I + P EIA + L S A Sbjct: 196 QRIRGFGEQFKLGIPLGKIARPQEIANTILFLASDLA 232 >2HSD-A nrPDB Length = 253 Score = 126 bits (317), Expect = 8e-30, Method: Composition-based stats. Identities = 52/268 (19%), Positives = 87/268 (32%), Gaps = 49/268 (18%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 I+TG RG+G ++ G ++ E TA + G Sbjct: 9 IITGGARGLGAEAARQAVAAGARVVLADVLDEEGAATARELGDAARY------------- 55 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 + + +D + E V+ L+N AG++ Sbjct: 56 ----------QHLDVTIEEDWQRVVAYAR------------EEFGSVDGLVNNAGISTGM 93 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 + + + ++ +N I M + +IVNISS + Sbjct: 94 FLETESVERFRKVVEINLTGVFIGMKTVIPAMKDA-----------GGGSIVNISSA--A 140 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEM 247 G M + TS Y ASK + +++ A E+ IR ++ PG+ T M + E Sbjct: 141 GLMGLALTSSYGASKWGVRGLSKLAAVELGTDRIRVNSVHPGMTY-TPMTAETGIRQGEG 199 Query: 248 LERTIGASGTSAPAEIAEEVWSLYSRTA 275 P EIA V L S T+ Sbjct: 200 NYPNTPMGRVGEPGEIAGAVVKLLSDTS 227 >3V8B-A nrPDB Length = 283 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 51/281 (18%), Positives = 97/281 (34%), Gaps = 52/281 (18%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 PVA++TGA GIG+A L G++ LG T+ +E A + Sbjct: 28 SPVALITGAGSGIGRATALALAADGVTVGALGRTRTEVEEVADEIVGAGGQAIALEA--- 84 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 D + + R ++ + ++++++ AG+ Sbjct: 85 ----------------DVSDELQMRNAVRDLV-------------LKFGHLDIVVANAGI 115 Query: 124 TQE-SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + + + + VN ++ + Y+ + IV +S Sbjct: 116 NGVWAPIDDLKPFEWDETIAVNLRGTFLTLHLTVPYLKQR-----------GGGAIVVVS 164 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG--TDMIQNL 240 SI + PG + Y+A+KAA + LA E+ +IR + PG ++ +D + Sbjct: 165 SINGTRTFTTPGATAYTATKAAQVAIVQQLALELGKHHIRVNAVCPGAIETNISDNTKLR 224 Query: 241 PVEAKEMLER------TIGASGTSAPAEIAEEVWSLYSRTA 275 E + I ++AE + L S A Sbjct: 225 HEEETAIPVEWPKGQVPITDGQPGRSEDVAELIRFLVSERA 265 >3OIC-A nrPDB Length = 258 Score = 125 bits (314), Expect = 2e-29, Method: Composition-based stats. Identities = 54/278 (19%), Positives = 100/278 (35%), Gaps = 49/278 (17%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQR 59 M A+VTG++RG+GKA +L + G + +I +K++ TA + +L + + Sbjct: 1 MEQNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVK 60 Query: 60 QCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN 119 +K+ + + +E +++ +N Sbjct: 61 A-----------------------NVGQPAKIKEMFQQI---------DETFGRLDVFVN 88 Query: 120 CAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 A + + MN+N + + K M K+ IV Sbjct: 89 NAASGVLRPVMELEETHWDWTMNINAKALLFCAQEAAKLMEKN-----------GGGHIV 137 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 +ISS+ + + SKAAL T LA E+ P+ I +S G + TD +++ Sbjct: 138 SISSL--GSIRYLENYTTVGVSKAALEALTRYLAVELSPKQIIVNAVSGGAID-TDALKH 194 Query: 240 LP--VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 P + E + A ++ + V L S A Sbjct: 195 FPNREDLLEDARQNTPAGRMVEIKDMVDTVEFLVSSKA 232 >1HXH-A nrPDB Length = 253 Score = 125 bits (313), Expect = 2e-29, Method: Composition-based stats. Identities = 52/277 (18%), Positives = 91/277 (32%), Gaps = 55/277 (19%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA+VTG G+G + + L +G + + ++ A + G+ R + Sbjct: 7 KVALVTGGASGVGLEVVKLLLGEGAKVAFSDINEAAGQQLAAELGE--------RSMFVR 58 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D W + + R +N+L+N AG+ Sbjct: 59 HDVSSEADWTLVMA---------------------------AVQRRLGTLNVLVNNAGIL 91 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 ++ +N S I M + +I+N++S+ Sbjct: 92 LPGDMETGRLEDFSRLLKINTESVFIGCQQGIAAMKE------------TGGSIINMASV 139 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRN--IRCFTISPGLVKGTDMIQNLPV 242 S + + + YSASKAA+S T A + IR +I P + M +LP Sbjct: 140 --SSWLPIEQYAGYSASKAAVSALTRAAALSCRKQGYAIRVNSIHPDGIYTPMMQASLPK 197 Query: 243 EAKEMLERTIG----ASGTSAPAEIAEEVWSLYSRTA 275 + + A P IA+ V L S + Sbjct: 198 GVSKEMVLHDPKLNRAGRAYMPERIAQLVLFLASDES 234 >1AHH-A nrPDB Length = 255 Score = 125 bits (313), Expect = 3e-29, Method: Composition-based stats. Identities = 51/269 (18%), Positives = 94/269 (34%), Gaps = 46/269 (17%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 AI+TGA GIGK I G S ++ ++ + QL G ++ +C I + Sbjct: 14 AIITGAGAGIGKEIAITFATAGASVVVSDINADAANHVVDEIQQL-GGQAFACRCDITSE 72 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + S + V++L+N AG Sbjct: 73 QELSALADFAIS-------------------------------KLGKVDILVNNAGGGGP 101 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + + +N S ++ + M K+ I+ I+S+ Sbjct: 102 KPF-DMPMADFRRAYELNVFSFFHLSQLVAPEMEKN-----------GGGVILTITSM-- 147 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 + + K + Y++SKAA S +A ++ +NIR I+PG + + + E ++ Sbjct: 148 AAENKNINMTSYASSKAAASHLVRNMAFDLGEKNIRVNGIAPGAILTDALKSVITPEIEQ 207 Query: 247 MLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + P +IA L S A Sbjct: 208 KMLQHTPIRRLGQPQDIANAALFLCSPAA 236 >5EJ2-A nrPDB Length = 308 Score = 124 bits (310), Expect = 6e-29, Method: Composition-based stats. Identities = 48/286 (16%), Positives = 93/286 (32%), Gaps = 47/286 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 VA ++GA RG G++ +L Q+G I + L+ Sbjct: 38 KVAFISGAARGQGRSHAVRLAQEGADIIAIDIC--GPIENLAYPHSTPEDLAETADLVKD 95 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +D + +D ++ ++ D S E+ +++++ AG+ Sbjct: 96 LDRRIVTAQVDVRDFEALKSAVD------------------SGVEQLGRLDIIVANAGVG 137 Query: 125 QESL-SVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + + + QD++++N + +++ R +IV SS Sbjct: 138 TDGRKLHKIRDNVWQDMIDINLTGVWHTVKAGVPHVLSGGR----------GGSIVLTSS 187 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGT-DMIQNL-- 240 + G+ P T Y A+K + A E+ P IR + P V T M Sbjct: 188 V--GGRKAYPNTGHYIAAKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFR 245 Query: 241 ---PVEAKEMLERTIGASGTS--------APAEIAEEVWSLYSRTA 275 P + S ++I+ V L S + Sbjct: 246 LFRPDLENPGPDDFAPISQMMHTLPVPWVDASDISNAVLFLASDES 291 >4EGF-A nrPDB Length = 266 Score = 123 bits (308), Expect = 9e-29, Method: Composition-based stats. Identities = 53/271 (19%), Positives = 93/271 (34%), Gaps = 46/271 (16%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A++TGAT+GIG I + G ++ G ++ + +R Sbjct: 23 ALITGATKGIGADIARAFAAAGARLVLSGRDVSELD-------------AARRALGEQFG 69 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 +D D E +++L+N AG++ Sbjct: 70 TDVHTVAIDLAEPDAPAELA------------------RRAAEAFGGLDVLVNNAGISHP 111 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 V T + VN +P + + K M+ + I+ ++ Sbjct: 112 QPVVDTDPQLFDATIAVNLRAPALLASAVGKAMVAA----------GEGGAIITVA--SA 159 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVEA 244 + +P Y SKA L T+VLA E+ P IR ++ P +V T+M Q + Sbjct: 160 AALAPLPDHYAYCTSKAGLVMATKVLARELGPHGIRANSVCPTVV-LTEMGQRVWGDEAK 218 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + I + P E+++ V L S A Sbjct: 219 SAPMIARIPLGRFAVPHEVSDAVVWLASDAA 249 >5O3Z-A nrPDB Length = 263 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 47/286 (16%), Positives = 86/286 (30%), Gaps = 53/286 (18%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA+V G + +G +C+ L Q G + + + R A Sbjct: 3 MAMEQVAVVIGGGQTLGAFLCEGLAQAGYHVAVADLNESNANRLADTINSRYGAGRAYGF 62 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 A D L + F +LL+ Sbjct: 63 KVDATDE------------------ASVEALARAVDETFGRA------------DLLVYS 92 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 AG+ + + + + + VN + + K M++ + I+ Sbjct: 93 AGVAKAAPITQFRLTDFDLSLQVNLVGYFLCSREFSKLMIRD----------GIKGRIIQ 142 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 I+S SGK+ S YSA+K T+ LA ++ I ++ G + + M Q+L Sbjct: 143 INS--KSGKVGSKHNSGYSAAKFGGVGLTQSLALDLAEYGITVHSLMLGNLLKSPMFQSL 200 Query: 241 -----------PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 P E + + ++ + S A Sbjct: 201 LPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDVLNVLLFYASDKA 246 >4DA9-A nrPDB Length = 280 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 56/270 (20%), Positives = 93/270 (34%), Gaps = 45/270 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 PVAIVTG RGIG I + L G I G + + Sbjct: 30 PVAIVTGGRRGIGLGIARALAASGFDIAITGIGDA------------------EGVAPVI 71 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + + + D + + + + ++ L+N AG+ Sbjct: 72 AELSGLGARVIFLRADLADLSSHQATVDAVVAE-------------FGRIDCLVNNAGIA 118 Query: 125 QES--LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + I+ VN V T +K M+ S R +I+NI+ Sbjct: 119 SIVRDDFLDLKPENFDTIVGVNLRGTVFFTQAVLKAMLASDARASR--------SIINIT 170 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV 242 S+ S M P Y SKA L+ F++ LA + I F + PG+++ +DM + Sbjct: 171 SV--SAVMTSPERLDYCMSKAGLAAFSQGLALRLAETGIAVFEVRPGIIR-SDMTAAVSG 227 Query: 243 EAKEMLER-TIGASGTSAPAEIAEEVWSLY 271 + ++E + P +I V L Sbjct: 228 KYDGLIESGLVPMRRWGEPEDIGNIVAGLA 257 >5JS6-A nrPDB Length = 274 Score = 119 bits (299), Expect = 9e-28, Method: Composition-based stats. Identities = 39/173 (22%), Positives = 70/173 (40%), Gaps = 24/173 (13%) Query: 110 RRYYVNLLINCAGLTQE-SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 R ++ ++N AG T+A + ++ +N + T+T + + Y+ KSQ Sbjct: 81 RFGRLDCVVNNAGHHPPPQRPEETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQ----- 135 Query: 169 LSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 ++NISS++ G + Y A+K A++ T+ LA + P +R ISP Sbjct: 136 -------GNVINISSLV--GAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISP 186 Query: 229 GLVKGTDMIQNL-------PVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRT 274 G + T + + L +E + PAE+ L S Sbjct: 187 GNI-WTPLWEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASEA 237 >4CR6-A nrPDB Length = 271 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 45/271 (16%), Positives = 80/271 (29%), Gaps = 46/271 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 AIVTGA GIG+A + ++G S + A+D + Y+ AI Sbjct: 16 KAAIVTGAAGGIGRATVEAYLREGASVV------------AMDLAPRLAATRYEEPGAIP 63 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 I + R +++L+ L Sbjct: 64 IACDLADRAAIDAAMADAVA-------------------------RLGGLDILVAGGALK 98 Query: 125 QE-SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + + + ++VN + M+ + I+ I S Sbjct: 99 GGTGNFLDLSDADWDRYVDVNMTGTFLTCRAGARAMVAAGA-----GKDGRSARIITIGS 153 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV- 242 + + M P + Y A+K ++ T +A ++ I I+PG V T Sbjct: 154 V--NSFMAEPEAAAYVAAKGGVAMLTRAMAVDLARHGILVNMIAPGPVDVTGNNTGYSEP 211 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 E + + P E+A L Sbjct: 212 RLAEQVLDEVALGRPGLPEEVATAAVFLAED 242 >3RKU-A nrPDB Length = 287 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 58/274 (21%), Positives = 100/274 (36%), Gaps = 54/274 (19%) Query: 8 IVTGATRGIGKAICQKLFQK---GLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 ++TGA+ GIGKA + + + I+ E +E Sbjct: 37 LITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKK-----------------T 79 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 ID + + D + K +P ++ D +++L+N AG Sbjct: 80 IDQEFPNAKVHVAQLDITQAEKIKPFIENLPQEFKD-------------IDILVNNAGKA 126 Query: 125 QESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 S V + IQD+ + N + + +T + IVN+ S Sbjct: 127 LGSDRVGQIATEDIQDVFDTNVTALINITQAVLPIFQAKN-----------SGDIVNLGS 175 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP-- 241 I +G+ P S+Y ASK A+ FT+ L E+ IR I+PGLV+ + Sbjct: 176 I--AGRDAYPTGSIYCASKFAVGAFTDSLRKELINTKIRVILIAPGLVETEFSLVRYRGN 233 Query: 242 -VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRT 274 +AK + + T ++A+ + SR Sbjct: 234 EEQAKNVYKDTTPL----MADDVADLIVYATSRK 263 >4TRR-A nrPDB Length = 269 Score = 116 bits (289), Expect = 1e-26, Method: Composition-based stats. Identities = 48/277 (17%), Positives = 93/277 (33%), Gaps = 55/277 (19%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A+VTGA GIGK I +L + G + I ++ A + + + +A Sbjct: 15 KTAVVTGAASGIGKEIALELAKAGAAVAIADLNQDGANAVADEINKAGG-----KAIGVA 69 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +D E V++L++ AG+ Sbjct: 70 MDVTNEEAV---------------------------NTGIDKVAEAFGSVDILVSNAGIQ 102 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + + + + ++ T +K+M K R ++ + S+ Sbjct: 103 IVNPIENYSFADWKKMQAIHVDGAFLTTKAALKHMYKDDR----------GGVVIYMGSV 152 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 P S Y +K L VLA E N+R + PG V+ + + +P +A Sbjct: 153 --HSHEASPLKSAYVTAKHGLLGLARVLAKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQA 210 Query: 245 KEM------LERTIGASG-----TSAPAEIAEEVWSL 270 KE+ + + + + ++A+ V L Sbjct: 211 KELGISEEEVIKKVMLGNTVDGVFTTVQDVAQTVLFL 247 >3UN1-A nrPDB Length = 260 Score = 114 bits (286), Expect = 3e-26, Method: Composition-based stats. Identities = 47/267 (17%), Positives = 81/267 (30%), Gaps = 58/267 (21%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V ++TGA++GIG + + + + + R + Sbjct: 29 KVVVITGASQGIGAGLVRAYRDRNYRVV-----------------------ATSRSIKPS 65 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D D + + ER ++ L+N AG+ Sbjct: 66 ADPDIHTVAGDISKPETADRIVREG------------------IERFGRIDSLVNNAGVF 107 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS-S 183 V T + VN +T M+K IV+I+ S Sbjct: 108 LAKPFVEMTQEDYDHNLGVNVAGFFHITQRAAAEMLKQ-----------GSGHIVSITTS 156 Query: 184 ILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 ++ + +P S +K L+ T LA E +R +SPG++K T M P E Sbjct: 157 LVDQPMVGMPSALA-SLTKGGLNAVTRSLAMEFSRSGVRVNAVSPGVIK-TPM---HPAE 211 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSL 270 L ++ + V L Sbjct: 212 THSTLAGLHPVGRMGEIRDVVDAVLYL 238 >3GDF-A nrPDB Length = 267 Score = 109 bits (273), Expect = 9e-25, Method: Composition-based stats. Identities = 39/277 (14%), Positives = 77/277 (27%), Gaps = 47/277 (16%) Query: 5 PVAIVTGAT--RGIGKAICQKLFQKGLSCII-LGSTKESIERTAIDRGQLQSGLSYQRQC 61 V +VTGA+ +G+G + + G + I S + E + + + +C Sbjct: 21 KVVVVTGASGPKGMGIEAARGCAEMGAAVAITYASRAQGAEENVKELEKTYGIKAKAYKC 80 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 + D ++ I A Sbjct: 81 QVDSYESCEKLVKDVV-------------------------------ADFGQIDAFIANA 109 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 G T +S + + ++ V+ + ++V Sbjct: 110 GATADSGILDGSVEAWNHVVQVDLNGTFHCAKAV-----------GHHFKERGTGSLVIT 158 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 +S+ + Y+ +KA LA E R +ISPG + T + +P Sbjct: 159 ASMSGHIANFPQEQTSYNVAKAGCIHMARSLANEW-RDFARVNSISPGYID-TGLSDFVP 216 Query: 242 VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 E +++ I E+ S + T Sbjct: 217 KETQQLWHSMIPMGRDGLAKELKGAYVYFASDASTYT 253 >1SNY-A nrPDB Length = 267 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 52/237 (21%), Positives = 89/237 (37%), Gaps = 32/237 (13%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 H + ++TG RG+G + + L L + + Q Sbjct: 20 HMNSI-LITGCNRGLGLGLVKALLN-----------------LPQPPQHLFTTCRNREQA 61 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 D K + D + + D +N+L N A Sbjct: 62 KELEDLAKNHSNIHILEIDLRNFDAYDKLVADIEGVTKDQ-----------GLNVLFNNA 110 Query: 122 GLTQESLSVRTTASQ-IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 G+ +S + SQ + D + N + P+ + C+ + K+ + R I+N Sbjct: 111 GIAPKSARITAVRSQELLDTLQTNTVVPIMLAKACLPLLKKAAKANESQPMGVGRAAIIN 170 Query: 181 ISSILHSGKMKVPGTS-VYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 +SSIL S + G Y SK+AL+ T+ L+ ++ P+ I C ++ PG VK TDM Sbjct: 171 MSSILGSIQGNTDGGMYAYRTSKSALNAATKSLSVDLYPQRIMCVSLHPGWVK-TDM 226 >3ZV3-A nrPDB Length = 281 Score = 109 bits (272), Expect = 1e-24, Method: Composition-based stats. Identities = 48/283 (16%), Positives = 98/283 (34%), Gaps = 66/283 (23%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA++TG G+G+A+ + +G +L + E + + G G+ Sbjct: 7 VALITGGASGLGRALVDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGV---------- 56 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + +D+ ++ F ++ LI AG+ Sbjct: 57 -------------VGDVRSLQDQKRAAERCLAAFGK------------IDTLIPNAGIWD 91 Query: 126 ESLSVRTTASQ-----IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 S ++ DI +VN + C+ ++ S+R ++V Sbjct: 92 YSTALADLPEDKIDAAFDDIFHVNVKGYIHAVKACLPALV------------SSRGSVVF 139 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM--IQ 238 S ++G G +Y+A+K A+ +A E+ P +R ++PG + TD+ Sbjct: 140 TIS--NAGFYPNGGGPLYTATKHAVVGLVRQMAFELAPH-VRVNGVAPGGMN-TDLRGPS 195 Query: 239 NLPVEAK--------EMLERTIGASGTSAPAEIAEEVWSLYSR 273 +L + + +ML+ + A E +R Sbjct: 196 SLGLSEQSISSVPLADMLKSVLPIGRMPALEEYTGAYVFFATR 238 >3PPI-A nrPDB Length = 281 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 46/268 (17%), Positives = 90/268 (33%), Gaps = 39/268 (14%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 AIV+G G+G+A ++L GL +I E + A + G +S Sbjct: 33 AIVSGGAGGLGEATVRRLHADGLGVVIADLAAEKGKALADELGNRAEFVS---------- 82 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + S D + + + + +R + ++ Sbjct: 83 -------TNVTSEDSVLAAIEAANQLGRLRYAVVAHGGFGVAQRI-----------VQRD 124 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 +++ + + + ++ R R +V +SI Sbjct: 125 GSPADM--GGFTKTIDLYLNGTYNVARLVAASIAAAEPRE-----NGERGALVLTASI-- 175 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 +G G + Y+A+KA + T A ++ IR TI+PG +K T +++++ EA Sbjct: 176 AGYEGQIGQTAYAAAKAGVIGLTIAAARDLSSAGIRVNTIAPGTMK-TPIMESVGEEALA 234 Query: 247 MLERTIGA-SGTSAPAEIAEEVWSLYSR 273 I P E A+ L + Sbjct: 235 KFAANIPFPKRLGTPDEFADAAAFLLTN 262 >3KZV-A nrPDB Length = 254 Score = 101 bits (251), Expect = 3e-22, Method: Composition-based stats. Identities = 54/243 (22%), Positives = 92/243 (37%), Gaps = 51/243 (20%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 V +VTG +RGIGK+I LF ++ G + R+ +L+ Sbjct: 1 MGKVILVTGVSRGIGKSIVDVLFSLDKDTVVYG-----VARSEAPLKKLKE--------- 46 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 K+ Y D + LKQ + K ++ L+ AG Sbjct: 47 ------KYGDRFFYVVGD----ITEDSVLKQLVNAAVKGHGK---------IDSLVANAG 87 Query: 123 LTQESLSV-RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 + + +V + + + ++NF S V++ I + + K +V + Sbjct: 88 VLEPVQNVNEIDVNAWKKLYDINFFSIVSLVGIALPELKK------------TNGNVVFV 135 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLP 241 SS + M Y +SKAAL+ F LA E R ++ ++PG+V TDM N+ Sbjct: 136 SS--DACNMYFSSWGAYGSSKAALNHFAMTLANE--ERQVKAIAVAPGIVD-TDMQVNIR 190 Query: 242 VEA 244 Sbjct: 191 ENV 193 >1W73-A nrPDB Length = 302 Score = 100 bits (248), Expect = 8e-22, Method: Composition-based stats. Identities = 45/254 (17%), Positives = 83/254 (32%), Gaps = 45/254 (17%) Query: 24 LFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIE 83 L G C+I + ++ TA + QC + Sbjct: 46 LSSLGAQCVIASRKMDVLKATAEQISSQTGNKVHAIQCDV-------------------- 85 Query: 84 YFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNV 143 +D ++ S L + N++IN A S + R + + + I ++ Sbjct: 86 --RDPDMVQNTVSELIKVA---------GHPNIVINNAAGNFISPTERLSPNAWKTITDI 134 Query: 144 NFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKA 203 +T K ++K+Q+ L +I I + SG + +++KA Sbjct: 135 VLNGTAFVTLEIGKQLIKAQKGAAFL-------SITTIYAETGSGFVVPS-----ASAKA 182 Query: 204 ALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA--KEMLERTIGASGTSAPA 261 + ++ LAAE +R I PG +K L ++ + I Sbjct: 183 GVEAMSKSLAAEWGKYGMRFNVIQPGPIKTKGAFSRLDPTGTFEKEMIGRIPCGRLGTVE 242 Query: 262 EIAEEVWSLYSRTA 275 E+A L S A Sbjct: 243 ELANLAAFLCSDYA 256 >1BDB-A nrPDB Length = 277 Score = 99.6 bits (246), Expect = 1e-21, Method: Composition-based stats. Identities = 43/282 (15%), Positives = 87/282 (30%), Gaps = 68/282 (24%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++TG G+G+A+ + +G +L + E + D G Sbjct: 9 LITGGASGLGRALVDRFVAEGAKVAVLDKSAERLAELETDHGD----------------- 51 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 D S + + R R ++ LI AG+ S Sbjct: 52 NVLGIVGDVRSLEDQKQAASRC------------------VARFGKIDTLIPNAGIWDYS 93 Query: 128 LS-----VRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + + + ++ ++N + C+ ++ S R ++ Sbjct: 94 TALVDLPEESLDAAFDEVFHINVKGYIHAVKACLPALVAS------------RGNVIFTI 141 Query: 183 SILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVK---------- 232 S ++G G +Y+A+K A+ LA E+ P +R + G + Sbjct: 142 S--NAGFYPNGGGPLYTAAKHAIVGLVRELAFELAPY-VRVNGVGSGGINSDLRGPSSLG 198 Query: 233 -GTDMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 G+ I +P +ML+ + E +R Sbjct: 199 MGSKAISTVP--LADMLKSVLPIGRMPEVEEYTGAYVFFATR 238 >3PXX-A nrPDB Length = 287 Score = 99.2 bits (245), Expect = 2e-21, Method: Composition-based stats. Identities = 47/295 (15%), Positives = 102/295 (34%), Gaps = 60/295 (20%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V +VTG RG G++ KL ++G I+ + + + A + Sbjct: 11 KVVLVTGGARGQGRSHAVKLAEEGADIILFDICHD--------------IETNEYPLATS 56 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D ++ ++ D L + ++ +++++ AG+ Sbjct: 57 RDLEEAGLEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEF------GKLDVVVANAGIC 110 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 D +V+F+ + + + Y+ ++ +I+ S+ Sbjct: 111 PLGA--HLPVQAFADAFDVDFVGVINTVHAALPYL-------------TSGASIITTGSV 155 Query: 185 LH---------SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTD 235 +G + PG + YS +K + +T LAA++ P++IR I P V TD Sbjct: 156 AGLIAAAQPPGAGGPQGPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVN-TD 214 Query: 236 MIQNLPVEAKEMLERTIGASG---------------TSAPAEIAEEVWSLYSRTA 275 M+ + P+ + + + ++I+ V L S + Sbjct: 215 MLNSAPMYRQFRPDLEAPSRADALLAFPAMQAMPTPYVEASDISNAVCFLASDES 269 >1A27-A nrPDB Length = 289 Score = 98.0 bits (242), Expect = 3e-21, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 82/277 (29%), Gaps = 57/277 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V ++TG + GIG + +L S + T D R A Sbjct: 4 VVLITGCSSGIGLHLAVRLASD-------PSQSFKVYATLRDLKTQGRLWEAARALACPP 56 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 LD + ++R V++L+ AGL Sbjct: 57 G-SLETLQLDVRDSKSVAAARERVT--------------------EGRVDVLVCNAGLGL 95 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + +++VN + V M + M + ++ S+ Sbjct: 96 LGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRR-----------GSGRVLVTGSV- 143 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVE 243 G M +P VY ASK AL E LA + P + I G V M + L P E Sbjct: 144 -GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEE 202 Query: 244 AKEMLE--------------RTIGASGTSAPAEIAEE 266 + + + + P E+AE Sbjct: 203 VLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 239 >5ILO-A nrPDB Length = 271 Score = 98.0 bits (242), Expect = 4e-21, Method: Composition-based stats. Identities = 45/240 (18%), Positives = 83/240 (34%), Gaps = 52/240 (21%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG GIG + ++L G + + + ++++E R + + +A Sbjct: 18 AVVTGGAGGIGLQVSKQLLAAGAAKVAIIDLQDNLEEFVKLRAAHPTQSVMIIKMDVANK 77 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + + +++++N AG+ + Sbjct: 78 KGVEATYEEIAKT-------------------------------FGNIDIVVNVAGIFND 106 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 +Q + VN + T + YM K +VN+SS++ Sbjct: 107 --------KDVQRTLLVNLGGIINSTLSALPYMGKDN--------GGKGGIVVNMSSVV- 149 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAE--MEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 G + VY A+KA + FT LA E + I+ T+ PG TDM N + Sbjct: 150 -GLDPMFIIPVYGATKAGIINFTRCLANEKYYQRSGIKFVTVCPGATM-TDMFTNFTEKI 207 >2BGM-A nrPDB Length = 278 Score = 97.6 bits (241), Expect = 4e-21, Method: Composition-based stats. Identities = 35/221 (15%), Positives = 74/221 (33%), Gaps = 23/221 (10%) Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 A D + S D I + + L D + ++++ Sbjct: 45 IADIADDHGQKVCNNIGSPDVISFVHCDVTKDEDVRNLVDTT-----IAKHGKLDIMFGN 99 Query: 121 AGLTQESL--SVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTI 178 G+ + + + +M++N + + M+ +++ +I Sbjct: 100 VGVLSTTPYSILEAGNEDFKRVMDINVYGAFLVAKHAARVMIPAKK-----------GSI 148 Query: 179 VNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 V +SI S + VY+A+K A+ T L E+ IR +SP +V + Sbjct: 149 VFTASI-SSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYIVASPLLTD 207 Query: 239 NLPVE---AKEMLERTIGASG-TSAPAEIAEEVWSLYSRTA 275 V+ +E+ + G ++A+ V L + Sbjct: 208 VFGVDSSRVEELAHQAANLKGTLLRAEDVADAVAYLAGDES 248 >3U4C-A nrPDB Length = 281 Score = 97.3 bits (240), Expect = 6e-21, Method: Composition-based stats. Identities = 52/287 (18%), Positives = 89/287 (31%), Gaps = 58/287 (20%) Query: 2 HYLP-VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 H A V GA++GIGKAI KL + S +I ++IE D S Sbjct: 20 HMSKRTAFVMGASQGIGKAIALKLADQHFSLVINSRNLDNIESVKEDILAKHPEASVIVL 79 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC 120 D + +++LIN Sbjct: 80 AGDMSDQHTRAGIFQ------------------------------KIESQCGRLDVLINN 109 Query: 121 AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 + + + T + + + +R L Q+ I+N Sbjct: 110 --------IPGGAPDTFDNCNIEDMTATFTQKTVAY---IDAIKRASSLMKQNEFGRIIN 158 Query: 181 ISSILHSGKMKVPGTSVYSAS--KAALSRFTEVLAAEMEPRNIRCFTISPGLVKG----- 233 I K PG ++++ S AAL ++ ++ ++ P NI ++PG + Sbjct: 159 I----VGNLWKEPGANMFTNSMMNAALINASKNISIQLAPHNITVNCLNPGFIATDRYHQ 214 Query: 234 ---TDMIQN--LPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 M +N +A+E + I + E A L S A Sbjct: 215 FVENVMKKNSISKQKAEEQIASGIPMKRVGSAEETAALAAFLASEEA 261 >6CGE-A nrPDB Length = 328 Score = 97.3 bits (240), Expect = 7e-21, Method: Composition-based stats. Identities = 51/277 (18%), Positives = 82/277 (29%), Gaps = 57/277 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V ++TG + GIG + +L S + T D R A Sbjct: 5 VVLITGCSSGIGLHLAVRLASD-------PSQSFKVYATLRDLKTQGRLWEAARALACPP 57 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 LD + ++R V++L+ AGL Sbjct: 58 G-SLETLQLDVRDSKSVAAARERVT--------------------EGRVDVLVCNAGLGL 96 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + +++VN + V M + M + ++ S+ Sbjct: 97 LGPLEALGEDAVASVLDVNVVGTVRMLQAFLPDMKRR-----------GSGRVLVTGSV- 144 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL--PVE 243 G M +P VY ASK AL E LA + P + I G V M + L P E Sbjct: 145 -GGLMGLPFNDVYCASKFALEGLCESLAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEE 203 Query: 244 AKEMLE--------------RTIGASGTSAPAEIAEE 266 + + + + P E+AE Sbjct: 204 VLDRTDIHTFHRFYQYLAHSKQVFREAAQNPEEVAEV 240 >4DRY-A nrPDB Length = 281 Score = 96.9 bits (239), Expect = 8e-21, Method: Composition-based stats. Identities = 48/254 (18%), Positives = 81/254 (31%), Gaps = 45/254 (17%) Query: 20 ICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESY 79 I Q L +G S +I G + ++ A + G + C + Sbjct: 49 IAQALSAEGYSVVITGRRPDVLDAAAGEIGGRTGNIVRAVVCDVG--------------- 93 Query: 80 DGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT-QESLSVRTTASQIQ 138 D + ++ + + ++LL+N AG T Q Sbjct: 94 -------DPDQVAALFAAVRAEFAR---------LDLLVNNAGSNVPPVPLEEVTFEQWN 137 Query: 139 DIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVY 198 I+ N T + M I+N SI S + P ++ Y Sbjct: 138 GIVAANLTGAFLCTQHAFRMMKAQ---------TPRGGRIINNGSI--SAQTPRPNSAPY 186 Query: 199 SASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTS 258 +A+K A++ T+ A + +I C I G TDM + + + A T Sbjct: 187 TATKHAITGLTKSTALDGRMHDIACGQIDIGN-AATDMTARMSTGVLQA-NGEVAAEPTI 244 Query: 259 APAEIAEEVWSLYS 272 IAE V + S Sbjct: 245 PIEHIAEAVVYMAS 258 >3E9N-A nrPDB Length = 245 Score = 96.1 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 51/274 (18%), Positives = 92/274 (33%), Gaps = 60/274 (21%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 +A+VTGAT G+G I + L + LG E + A G Sbjct: 6 KIAVVTGATGGMGIEIVKDLSRD-HIVYALGRNPEHLAALAEIEG--------------- 49 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 P++ + +V+ L++ A + Sbjct: 50 -----------------------VEPIESDIVKEVLEEGGVDKLKNLDHVDTLVHAAAVA 86 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 +++ + ++ +++N + P ++ + + + ++ I+S Sbjct: 87 RDTTIEAGSVAEWHAHLDLNVIVPAELSRQLLPALRAAS------------GCVIYINS- 133 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 +G PG ++Y+ASK AL + E IR T+SPG T M+Q L Sbjct: 134 -GAGNGPHPGNTIYAASKHALRGLADAFRKEEANNGIRVSTVSPGPTN-TPMLQGLMDSQ 191 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 I P EIA + + A ET Sbjct: 192 GTNFRPEI----YIEPKEIANAIRFVI--DAGET 219 >4RGB-A nrPDB Length = 294 Score = 94.6 bits (233), Expect = 4e-20, Method: Composition-based stats. Identities = 42/280 (15%), Positives = 92/280 (32%), Gaps = 42/280 (15%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V +TGA RG G++ ++G + + + E I +L + + + Sbjct: 27 VVFITGAARGQGRSHAVMCAEQGANIV----GVDICEDIDIVPYKLGTYEELEETARLVE 82 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + + + D K +FD E+ +++ +I AG+ Sbjct: 83 KTGQEMLFRKADVRD-----------KAVLQEVFDA-----GVEQFGHIDTVIANAGVVL 126 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + R + ++ +++ + + I +M + + ++ SS++ Sbjct: 127 TNPDERDASEALRLGLDIMLIGVWNTFQVAIPHMKE----------RGQGGNLIATSSMI 176 Query: 186 HSGKM--KVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE 243 + GT Y SK A++ A + IR ++P T MI P Sbjct: 177 ALLDLTDGRGGTDAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNC-STPMITENPAL 235 Query: 244 AK---------EMLERTIGASGTSAPAEIAEEVWSLYSRT 274 K + + P +++ + L S Sbjct: 236 FKVIEENPHLVNAMSTALPDFPMIEPRDVSNAILFLISDA 275 >1B15-A nrPDB Length = 254 Score = 89.2 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 51/239 (21%), Positives = 81/239 (33%), Gaps = 50/239 (20%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V V A GIG ++L ++ L ++ E+ A AI Sbjct: 8 VIFV-AALGGIGLDTSRELVKRNLKNFVILDRVENPTALA-------------ELKAINP 53 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 H D K+ +FD V++LIN AG+ Sbjct: 54 KVNITFHTYDVTVP--------VAESKKLLKKIFDQLKT---------VDILINGAGILD 96 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + QI+ + +NF V T + + K + I NI S+ Sbjct: 97 DH--------QIERTIAINFTGLVNTTTAILDFWDKRK--------GGPGGIIANICSV- 139 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 +G + VYSASKAA+ FT LA + ++I+PG + T ++ Sbjct: 140 -TGFNAIHQVPVYSASKAAVVSFTNSLAKLAPITGVTAYSINPG-ITRTPLVHTFNSWL 196 >5JY1-A nrPDB Length = 274 Score = 88.8 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 46/271 (16%), Positives = 84/271 (30%), Gaps = 48/271 (17%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTGA GIG+ + + +G + II + + + + ++ Sbjct: 16 VALVTGAGGGIGRGVARSFGNEGAAVIIAEINESTGRQVEQEIREMGG------------ 63 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL-T 124 S + ++ + E+ +++L+N A + T Sbjct: 64 -----------RSLFVKTDVTSKASIEAAVRSAV---------EQFGSLDILVNNAFVPT 103 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 L T ++ + + + M + RRW IVN SI Sbjct: 104 PNVLLEEKTDEMLEQTLTTSLWATWWAMRAAFVPMRE--RRW---------GRIVNFYSI 152 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM-IQNLPVE 243 + G Y+ +KA + T A+E NI I+P + T + E Sbjct: 153 DTETGAWLHG--DYNTAKAGIVGLTRSAASEWGRFNITVNAIAPTAMGATFFELAAKNPE 210 Query: 244 AKEMLERTIGASGTSAPA-EIAEEVWSLYSR 273 E + P +I S Sbjct: 211 FAERSAAARPLGRSGDPEQDIGPAAVFFASE 241 >3DWF-A nrPDB Length = 276 Score = 85.7 bits (210), Expect = 2e-17, Method: Composition-based stats. Identities = 43/216 (19%), Positives = 78/216 (36%), Gaps = 45/216 (20%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 IVTGA++GIG+ I L + G ++ +KE++++ +L + ++ ++ Sbjct: 15 IVTGASKGIGREIAYHLAKMGAHVVVTARSKEALQKVVARCLELGAASAHYIAGSME--- 71 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 F +++LI L Sbjct: 72 ----------------------------DMTFAEEFVAEAGNLMGGLDMLILNHVLYNRL 103 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 ++ M VNF S V ++ + +M+SQ +I +SS+ + Sbjct: 104 TFFHGEIDNVRKSMEVNFHSFVVLSVAAMPMLMQSQ------------GSIAVVSSV--A 149 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRC 223 GK+ P + YSASK AL F L +E + Sbjct: 150 GKITYPLIAPYSASKFALDGFFSTLRSEFLVNKVNV 185 >1MG5-A nrPDB Length = 255 Score = 85.3 bits (209), Expect = 2e-17, Method: Composition-based stats. Identities = 32/126 (25%), Positives = 54/126 (42%), Gaps = 18/126 (14%) Query: 109 ERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 + V++LIN AG+ + QI+ + VN+ V T + + K + Sbjct: 81 AQLKTVDVLINGAGILDDH--------QIERTIAVNYTGLVNTTTAILDFWDKRKG---- 128 Query: 169 LSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 I NI S+ +G + VYS +KAA+ FT LA + +T++P Sbjct: 129 ----GPGGIICNIGSV--TGFNAIYQVPVYSGTKAAVVNFTSSLAKLAPITGVTAYTVNP 182 Query: 229 GLVKGT 234 G+ + T Sbjct: 183 GITRTT 188 >4GKB-A nrPDB Length = 258 Score = 84.5 bits (207), Expect = 5e-17, Method: Composition-based stats. Identities = 53/281 (18%), Positives = 88/281 (31%), Gaps = 56/281 (19%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 V IVTG GIG AI +L ++ ++ + A Sbjct: 8 KVVIVTGGASGIGGAISMRLAEERAIPVVFAR--------------------HAPDGAFL 47 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + Y + + + R + Q +T ++ L+N AG+ Sbjct: 48 DALAQRQPRATYLPVELQDDAQCRDAVAQTIAT-------------FGRLDGLVNNAGVN 94 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + + + N + M + C+ ++ R IVNISS Sbjct: 95 -DGIGLDAGRDAFVASLERNLIHYYAMAHYCVPHLKA------------TRGAIVNISS- 140 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN----- 239 + TS Y ASK A T A + +R + P V T + +N Sbjct: 141 -KTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVM-TPLYRNWIATF 198 Query: 240 -LPVEAKEMLERTIGAS-GTSAPAEIAEEVWSLYSRTALET 278 P + + + P EIA+ L S A T Sbjct: 199 EDPEAKLAEIAAKVPLGRRFTTPDEIADTAVFLLSPRASHT 239 >5PGZ-A nrPDB Length = 276 Score = 83.8 bits (205), Expect = 7e-17, Method: Composition-based stats. Identities = 40/216 (18%), Positives = 76/216 (35%), Gaps = 45/216 (20%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 IVTGA++GIG+ + L + G ++ ++E +++ +L + ++ + Sbjct: 22 IVTGASKGIGREMAYHLSKMGAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTME--- 78 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 F + +++LI Sbjct: 79 ----------------------------DMTFAEQFIVKAGKLMGGLDMLILNHITQTSL 110 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 ++ +M VNF+S V M+ + + +S +I ISS+ + Sbjct: 111 SLFHDDIHSVRRVMEVNFLSYVVMSTAALPMLKQS------------NGSIAVISSL--A 156 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRC 223 GKM P + YSASK AL F + E+ + Sbjct: 157 GKMTQPMIAPYSASKFALDGFFSTIRTELYITKVNV 192 >2HRB-A nrPDB Length = 274 Score = 79.9 bits (195), Expect = 1e-15, Method: Composition-based stats. Identities = 58/321 (18%), Positives = 92/321 (28%), Gaps = 109/321 (33%) Query: 4 LPVAIVTGATRGIGKAICQKLFQK-GLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 VA+VTGA RGIG AI ++L ++ ++ + Sbjct: 2 SRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQL-------------- 47 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 A H LD + I +D + +N+L+N A Sbjct: 48 QAEGLSPRFHQLDIDDLQSIRALRD------------------FLRKEYGGLNVLVNNAA 89 Query: 123 LTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNIS 182 + +S + + + NF + M N + M +VNIS Sbjct: 90 VAFKSDDPMPFDIKAEMTLKTNFFATRNMCNELLPIMKP-------------HGRVVNIS 136 Query: 183 SI---------------------LHSGKM-------------------KVPGTSVYSASK 202 S+ L G + P S Y SK Sbjct: 137 SLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTKNEVHEREGWPN-SPYGVSK 195 Query: 203 AALSRFTEVLAAEMEPR----NIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTS 258 ++ + +LA ++ + I PG VK TDM + K+ + Sbjct: 196 LGVTVLSRILARRLDEKRKADRILVNACCPGPVK-TDM------DGKDSIRTV------- 241 Query: 259 APAEIAEEVWSLY--SRTALE 277 E AE L A E Sbjct: 242 --EEGAETPVYLALLPPDATE 260 >4Z3K-A nrPDB Length = 275 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 60/284 (21%), Positives = 103/284 (36%), Gaps = 51/284 (17%) Query: 6 VAIVTGATRGIGKA---ICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 V ++TGA+RG G+ + L G ++ E++ + + G +SGL R A Sbjct: 23 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 82 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 L+Q L + LLIN AG Sbjct: 83 ---------------------DLGAEAGLQQLLGALRELPRPKGLQRL-----LLINNAG 116 Query: 123 LTQE--SLSVRTTAS-QIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 + V + S Q+ + +N S + +T+ +K T+V Sbjct: 117 SLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAF---------PDSPGLNRTVV 167 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ- 238 NISS+ G ++Y A KAA +VLA E N+R +PG + TDM Q Sbjct: 168 NISSL--CALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLD-TDMQQL 222 Query: 239 ----NLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 ++ + ++ L+ A+++ SL + ++ Sbjct: 223 ARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKS 266 >4HWK-A nrPDB Length = 288 Score = 79.1 bits (193), Expect = 2e-15, Method: Composition-based stats. Identities = 60/284 (21%), Positives = 103/284 (36%), Gaps = 51/284 (17%) Query: 6 VAIVTGATRGIGKA---ICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 V ++TGA+RG G+ + L G ++ E++ + + G +SGL R A Sbjct: 36 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 95 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 L+Q L + LLIN AG Sbjct: 96 ---------------------DLGAEAGLQQLLGALRELPRPKGLQRL-----LLINNAG 129 Query: 123 LTQE--SLSVRTTAS-QIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 + V + S Q+ + +N S + +T+ +K T+V Sbjct: 130 SLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAF---------PDSPGLNRTVV 180 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ- 238 NISS+ G ++Y A KAA +VLA E N+R +PG + TDM Q Sbjct: 181 NISSL--CALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLD-TDMQQL 235 Query: 239 ----NLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 ++ + ++ L+ A+++ SL + ++ Sbjct: 236 ARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKS 279 >1N5D-A nrPDB Length = 288 Score = 77.2 bits (188), Expect = 7e-15, Method: Composition-based stats. Identities = 45/265 (16%), Positives = 83/265 (31%), Gaps = 66/265 (24%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 VA+VTGA +GIG AI + L ++ ++L + + + A+ + Q + Q I Sbjct: 4 TRVALVTGANKGIGFAIVRDLCRQFAGDVVLTARDVARGQAAVKQLQAEGLSPRFHQLDI 63 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 D ++ L + +++L+N A + Sbjct: 64 ----------------------IDLQSIRALCDFL---------RKEYGGLDVLVNNAAI 92 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISS 183 + + Q + M NFM + + + R S + R +N S Sbjct: 93 AFQLDNPTPFHIQAELTMKTNFMGTRNVCTELLPLIKPQGRVVNVSSTEGVRA--LNECS 150 Query: 184 -----------ILHSGKMKVPGT-----------------SVYSASKAALSRFTEVLAAE 215 I + + S Y +K +S + + A + Sbjct: 151 PELQQKFKSETITEEELVGLMNKFVEDTKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARK 210 Query: 216 M----EPRNIRCFTISPGLVKGTDM 236 + I PG V+ TDM Sbjct: 211 LREQRAGDKILLNACCPGWVR-TDM 234 >3BHI-A nrPDB Length = 276 Score = 76.5 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 52/310 (16%), Positives = 90/310 (29%), Gaps = 105/310 (33%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA+VTG +GIG AI + L + ++L + + + A+ + Q + Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGDVVLTARDVTRGQAAVQQLQAEG------------ 53 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 H LD + I +D + +++L+N AG+ Sbjct: 54 -LSPRFHQLDIDDLQSIRALRDF------------------LRKEYGGLDVLVNNAGIAF 94 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + Q + M NF + + + +VN+SSI+ Sbjct: 95 KVADPTPFHIQAEVTMKTNFFGTRDVCTELLPLIKPQ-------------GRVVNVSSIM 141 Query: 186 H----------------------------------------SGKMKVPGTSVYSASKAAL 205 K P S Y +K + Sbjct: 142 SVRALKSCSPELQQKFRSETITEEELVGLMNKFVEDTKKGVHQKEGWPS-SAYGVTKIGV 200 Query: 206 SRFTEVLAAEMEPR----NIRCFTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPA 261 + + + A ++ + I PG V+ TDM G T +P Sbjct: 201 TVLSRIHARKLSEQRKGDKILLNACCPGWVR-TDMA---------------GPKATKSPE 244 Query: 262 EIAEEVWSLY 271 E AE L Sbjct: 245 EGAETPVYLA 254 >1OAA-A nrPDB Length = 259 Score = 74.1 bits (180), Expect = 6e-14, Method: Composition-based stats. Identities = 48/247 (19%), Positives = 86/247 (34%), Gaps = 46/247 (18%) Query: 6 VAIVTGATRGIGKAICQKLFQK---GLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 V ++TGA+RG G+A+ +L + G ++ ++ + + + G Q L Sbjct: 8 VCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLK------ 61 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 + + L + E + LLIN A Sbjct: 62 -------------------VVLAAADLGTEAGVQRLLSAVRELPRPEGLQRL-LLINNAA 101 Query: 123 LTQESLSVRTTASQIQDI---MNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 + + + ++ +N S + +T+ + S T+V Sbjct: 102 TLGDVSKGFLNVNDLAEVNNYWALNLTSMLCLTSGTLNAFQDS---------PGLSKTVV 152 Query: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 NISS+ G +Y A KAA +VLAAE +R + +PG + DM Q Sbjct: 153 NISSL--CALQPYKGWGLYCAGKAARDMLYQVLAAEEPS--VRVLSYAPGPLDN-DMQQL 207 Query: 240 LPVEAKE 246 +K+ Sbjct: 208 ARETSKD 214 >5L51-A nrPDB Length = 324 Score = 73.4 bits (178), Expect = 1e-13, Method: Composition-based stats. Identities = 53/305 (17%), Positives = 90/305 (29%), Gaps = 116/305 (38%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTGA +GIG IC++L KG++ I+ ++ +++ ++ Sbjct: 18 AVVTGANKGIGFEICKQLASKGITVILASRD---------EKRGIEARERLIKELGSEFG 68 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT-- 124 LD + D K +++L+N AGL Sbjct: 69 DYVVSQQLDVADPASVAALVDFIKTK------------------FGSLDILVNNAGLNGT 110 Query: 125 ----QESLSVRTTASQI----------------------------QDIMNVNFMSPVTMT 152 S+ ++ ++ + N+ +T Sbjct: 111 YMEGDASVLNDYVEAEFKTFQSGAAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVT 170 Query: 153 NICIKYMMKSQRRWPELSGQSARPTIVNISSILHS----------GKMKV---------- 192 I + +S P IVN+SS L S G Sbjct: 171 EALIPLLQQSD-----------SPRIVNVSSTLSSLVFQTNEWAKGVFSSEEGLTEEKLE 219 Query: 193 ---------------------PGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLV 231 P S Y SKAAL+ +T ++A + R + PG Sbjct: 220 EVLAEFLKDFIDGKQQEKQWPPHFSAYKVSKAALNAYTRIIAKKYPS--FRINAVCPGYT 277 Query: 232 KGTDM 236 K TD+ Sbjct: 278 K-TDL 281 >3O26-A nrPDB Length = 311 Score = 73.0 bits (177), Expect = 1e-13, Method: Composition-based stats. Identities = 50/301 (16%), Positives = 85/301 (28%), Gaps = 115/301 (38%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 A+VTG +GIG IC++L G+ ++ Sbjct: 15 AVVTGGNKGIGFEICKQLSSNGIMVVLTCRDVTKGHEAVEKLKN---------------- 58 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT-- 124 + + D + L T F +++L+N AG+ Sbjct: 59 --SNHENVVFHQLDVTDPIATMSSLADFIKTHFGK------------LDILVNNAGVAGF 104 Query: 125 ----------------------------QESLSVRTTASQIQDIMNVNFMSPVTMTNICI 156 + + T ++ + +N+ ++T + I Sbjct: 105 SVDADRFKAMISDIGEDSEELVKIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLI 164 Query: 157 KYMMKSQRRWPELSGQSARPTIVNISS---------------ILHSG------------- 188 + S P IVN+SS IL G Sbjct: 165 PLLQLSD-----------SPRIVNVSSSTGSLKYVSNETALEILGDGDALTEERIDMVVN 213 Query: 189 ------------KMKVPGT-SVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTD 235 P + Y+ SKA L+ +T VLA ++ + PGLVK T+ Sbjct: 214 MLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRVLANKIPKFQ--VNCVCPGLVK-TE 270 Query: 236 M 236 M Sbjct: 271 M 271 >2P91-A nrPDB Length = 285 Score = 72.6 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 42/276 (15%), Positives = 83/276 (30%), Gaps = 54/276 (19%) Query: 7 AIVTGAT--RGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A++TG R I I + ++G +T + +R S L + ++ Sbjct: 24 ALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSDLVVKCDVSLD 83 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D K +L+ E ++++++ Sbjct: 84 EDIKNLKKFLE---------------------------------ENWGSLDIIVHSIAYA 110 Query: 125 QE----SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 + + T+ + M+++ S + +T + M + IV Sbjct: 111 PKEEFKGGVIDTSREGFKIAMDISVYSLIALTRELLPLM------------EGRNGAIVT 158 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 +S + + VP +V +KAAL LA ++ R IS G VK Sbjct: 159 LS--YYGAEKVVPHYNVMGIAKAALESTVRYLAYDIAKHGHRINAISAGPVKTLAAYSIT 216 Query: 241 PVE-AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E + ++ + L S A Sbjct: 217 GFHLLMEHTTKVNPFGKPITIEDVGDTAVFLCSDWA 252 >3U9L-A nrPDB Length = 324 Score = 68.7 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 49/275 (17%), Positives = 96/275 (34%), Gaps = 45/275 (16%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 + ++TGA+ G G+ + L G S ++ + R A + + A Sbjct: 6 KIILITGASSGFGRLTAEALAGAGHRV--YASMRDIVGRNASNVEAIAGF-------ARD 56 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D LD +S ++ D+ + +++LI+ AG Sbjct: 57 NDVDLRTLELDVQSQVSVDRAIDQIIGED------------------GRIDVLIHNAGHM 98 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + T Q ++ ++N +S + + +M + + ++ ISS Sbjct: 99 VFGPAEAFTPEQFAELYDINVLSTQRVNRAALPHMRRQK-----------HGLLIWISSS 147 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPG-LVKGTD--MIQNLP 241 +G P + Y A+KAA+ A E+ I I PG GT+ +P Sbjct: 148 SSAGGTP-PYLAPYFAAKAAMDAIAVQYARELSRWGIETSIIVPGAFTSGTNHFAHSGVP 206 Query: 242 VE-AKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + A++ +G EI + ++ A Sbjct: 207 DDHARQAEYEAGPNAGLG--EEIKKAFAAIVPPDA 239 >2YW9-A nrPDB Length = 261 Score = 68.0 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 47/277 (16%), Positives = 86/277 (31%), Gaps = 57/277 (20%) Query: 7 AIVTGAT--RGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A+V G T R +G AI KL + G + + L L ++ Sbjct: 11 ALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGGALLFRADV--- 67 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 L ++ + E ++ L++ Sbjct: 68 ---------------------TQDEELDALFAGV---------KEAFGGLDYLVHAIAFA 97 Query: 125 Q----ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN 180 E + T + V+ S V + + + IV Sbjct: 98 PREAMEGRYIDTRRQDWLLALEVSAYSLVAVARRAEPLLRE-------------GGGIVT 144 Query: 181 ISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNL 240 ++ ++ + VP +V + +KAAL LA E+ P+ +R IS G V+ T +++ Sbjct: 145 LT--YYASEKVVPKYNVMAIAKAALEASVRYLAYELGPKGVRVNAISAGPVR-TVAARSI 201 Query: 241 PVEAK--EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 P K + + +T E+ L S A Sbjct: 202 PGFTKMYDRVAQTAPLRRNITQEEVGNLGLFLLSPLA 238 >3OIG-A nrPDB Length = 266 Score = 64.1 bits (154), Expect = 5e-11, Method: Composition-based stats. Identities = 39/262 (14%), Positives = 86/262 (32%), Gaps = 45/262 (17%) Query: 14 RGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHW 73 R I I + L + G I + + + G L S C + D Sbjct: 19 RSIAWGIARSLHEAGARLIFTYAGERLEKSVHELAGTLDRNDSIILPCDVTND------- 71 Query: 74 LDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTT 133 ++ ++++ + G+ ++ Sbjct: 72 ---------------AEIETCFASIKEQVGVI---------------HGIAH-CIAFANK 100 Query: 134 ASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVP 193 + + +N N + + Y + + + +IV ++ G++ +P Sbjct: 101 EELVGEYLNTNRDG-FLLAHNISSYSLTAVVKAARPMMTEG-GSIVTLT--YLGGELVMP 156 Query: 194 GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--EAKEMLERT 251 +V +KA+L + LAA++ NIR +IS G ++ T + + + +E Sbjct: 157 NYNVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIR-TLSAKGISDFNSILKDIEER 215 Query: 252 IGASGTSAPAEIAEEVWSLYSR 273 T+ P E+ + L+S Sbjct: 216 APLRRTTTPEEVGDTAAFLFSD 237 >2DKN-A nrPDB Length = 255 Score = 64.1 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 45/288 (15%), Positives = 91/288 (31%), Gaps = 72/288 (25%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 + V +TG+ GIG A+ + L + G + I + + IE G ++ Sbjct: 1 MSVIAITGSASGIGAALKELLARAGHTVIGIDRGQADIEADLSTPGGRET---------- 50 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + + D C ++ L+ CAG+ Sbjct: 51 ------------------------------AVAAVLDRCG--------GVLDGLVCCAGV 72 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTM----TNICIKYMMKSQRRWPELSGQSARPTIV 179 TA+ ++ VN+ + + + ++ + Sbjct: 73 -------GVTAANSGLVVAVNYFGVSALLDGLAEALSRGQQPAAVIVGSIAATQPGAAEL 125 Query: 180 NISSILHSGKMK-------VPGTS--VYSASKAALSRFTEVLAAEMEPRNIRCFTISPGL 230 + + +G G + Y+ SK A++ + R +R ++PG Sbjct: 126 PMVEAMLAGDEARAIELAEQQGQTHLAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGA 185 Query: 231 VKGTDMIQNLPVEAK--EMLERTI-GASGTSAPAEIAEEVWSLYSRTA 275 V+ T ++Q + + E R + S P E+AE + L A Sbjct: 186 VE-TPLLQASKADPRYGESTRRFVAPLGRGSEPREVAEAIAFLLGPQA 232 >2O2S-A nrPDB Length = 315 Score = 61.0 bits (146), Expect = 6e-10, Method: Composition-based stats. Identities = 34/279 (12%), Positives = 75/279 (26%), Gaps = 22/279 (7%) Query: 7 AIVTGATR--GIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A V G G G AI + L G + + ++ Sbjct: 12 AFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLPDGSLI 71 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 +P ++ + + + +++L++ Sbjct: 72 EFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH----- 126 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 S+ + ++ + + ++ + + + + + V +S + Sbjct: 127 ----SLANGPEVTKPLLETSRKGYLAASSNSAYSFVSLLQHFGPIMNEGGSA--VTLSYL 180 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEME-PRNIRCFTISPGLVKGTDMIQNLPVE 243 + G + S++KAAL T LA E +R IS G +K Sbjct: 181 AAERVVPGYGGGM-SSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSG 239 Query: 244 AKEMLERTI-------GASGTSAPAEIAEEVWSLYSRTA 275 K ++ I ++ L S A Sbjct: 240 EKSFIDYAIDYSYNNAPLRRDLHSDDVGGAALFLLSPLA 278 >4Q9N-A nrPDB Length = 298 Score = 59.9 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 40/281 (14%), Positives = 82/281 (29%), Gaps = 24/281 (8%) Query: 3 YLPVAIVTGATR--GIGKAICQKLFQKGLSCIILG-STKESIERTAIDRGQLQSGLSYQR 59 +A + G G G I + L + G + ++ I +++ G+ + Sbjct: 7 TGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNASRELSN 66 Query: 60 QCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN 119 + D + + K + ++++L++ Sbjct: 67 GELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKK-HFGHIDILVH 125 Query: 120 CAGLTQE--SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPT 177 + E + T+ ++ + S +++ + M Sbjct: 126 SLANSPEIAKPLLDTSRKGYLAALSTSSYSFISLLSHFGPIMNAGAST------------ 173 Query: 178 IVNISSILHSGKMKVPGTSV-YSASKAALSRFTEVLAAEMEPR-NIRCFTISPGLVKG-T 234 IS + VPG +A+KAAL T+VLA E R +R TIS G + Sbjct: 174 ---ISLTYLASMRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLASRA 230 Query: 235 DMIQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + + ++ L S A Sbjct: 231 GKAIGFIERMVDYYQDWAPLPSPMEAEQVGAAAAFLVSPLA 271 >5WQO-A nrPDB Length = 234 Score = 59.1 bits (141), Expect = 2e-09, Method: Composition-based stats. Identities = 40/242 (16%), Positives = 73/242 (30%), Gaps = 50/242 (20%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++ GA+RGIG + Q+G + + Q + + +R A+ D Sbjct: 10 LIVGASRGIGLGLADAFLQRGAQVFAVARRPQG-----SPGLQALAERAGERLQAVTGDL 64 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT--Q 125 + D + ++ LI AG+ Q Sbjct: 65 NQ-----------------------------HDCAERIGEMLGERRIDRLIVNAGIYGPQ 95 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + A Q + N ++P+ + S + +SS + Sbjct: 96 QQDVAEIDAEQTAQLFLTNAIAPLRLARAL-------------SGRVSRGGVVAFMSSQM 142 Query: 186 HSGKMK-VPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEA 244 S + +Y ASKAAL+ E E + PG V+ + P+ Sbjct: 143 ASLALGLSATMPLYGASKAALNSLVRSWEGEFEELPFSLLLLHPGWVRTEMGGDSAPLSV 202 Query: 245 KE 246 +E Sbjct: 203 EE 204 >5YCX-A nrPDB Length = 266 Score = 57.6 bits (137), Expect = 6e-09, Method: Composition-based stats. Identities = 42/264 (15%), Positives = 77/264 (29%), Gaps = 45/264 (17%) Query: 14 RGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHW 73 R I I + L G I + + L+ S C + D Sbjct: 20 RSIAWGIARSLHNAGAKLIFTYAGERLERNVRELADTLEGQESLVLPCDVTNDE------ 73 Query: 74 LDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTT 133 E +KQ+ T+ + + R + V T+ Sbjct: 74 ---------ELTACFETIKQEVGTIHGVAHCIAFANRDDL------------KGEFVDTS 112 Query: 134 ASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVP 193 N++ S + K M + I+ ++ G+ V Sbjct: 113 RDGFLLAQNISAFSLTAVAREAKKVM-------------TEGGNILTLT--YLGGERVVK 157 Query: 194 GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--EAKEMLERT 251 +V +KA+L + LA ++ IR IS G ++ T + + +E Sbjct: 158 NYNVMGVAKASLEASVKYLANDLGQHGIRVNAISAGPIR-TLSAKGVGDFNSILREIEER 216 Query: 252 IGASGTSAPAEIAEEVWSLYSRTA 275 T+ E+ + L+S A Sbjct: 217 APLRRTTTQEEVGDTAVFLFSDLA 240 >5TF4-A nrPDB Length = 274 Score = 57.2 bits (136), Expect = 8e-09, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 64/172 (37%), Gaps = 22/172 (12%) Query: 108 NERRYYVNLLINCAGLTQESLS----VRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQ 163 ++ ++ L++ G + + V + S MN++ S +T K M Sbjct: 85 EKKWGKLDFLVHAIGFSDKEELSGRYVDISESNFMMTMNISVYSLTALTKRAEKLM---- 140 Query: 164 RRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRC 223 S +I+ ++ + + VP +V +KAAL + LA ++ P++IR Sbjct: 141 ---------SDGGSILTLT--YYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRV 189 Query: 224 FTISPGLVKGTDMIQNLPVE--AKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 IS G +K T + + E T E+ + L S Sbjct: 190 NAISAGPIK-TLAASGIGDFRYILKWNEYNAPLRRTVTIEEVGDSALYLLSD 240 >5LCX-A nrPDB Length = 316 Score = 56.4 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 51/290 (17%), Positives = 86/290 (29%), Gaps = 82/290 (28%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTK----ESIERTAIDRGQLQSGLS------ 56 A+VTGA +GIG IC++L +KG+ I+ + E+ ++ + ++ L Sbjct: 10 ALVTGANKGIGFEICRQLAEKGIIVILTSRNEKRGLEARQKLLKELNVSENRLVFHQLDV 69 Query: 57 ------YQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNER 110 I F K ++ G+E D + F + Sbjct: 70 TDLASVAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFKALQALEAGAK 129 Query: 111 RYYVNLLINCAGLTQESLSVRTTA--SQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPE 168 + + +D + N+ P +T I + Sbjct: 130 EEPP---------FKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQ-------- 172 Query: 169 LSGQSARPTIVNISSILHS----------GKMK--------------------------- 191 S P IVN+SS S G + Sbjct: 173 ---LSPSPRIVNVSSSFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLE 229 Query: 192 ----VPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMI 237 P + SKAAL+ +T++ A + R I PG TD+ Sbjct: 230 ESQWPPHFAAERVSKAALNAYTKIAAKKYPS--FRINAICPGY-AKTDIT 276 >3UCF-A nrPDB Length = 223 Score = 56.0 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 38/182 (20%), Positives = 60/182 (32%), Gaps = 21/182 (11%) Query: 92 KQKYSTLFDPCNKWSNNERRYYVNLLINCAG-LTQESLSVRTTASQIQDIMNVNFMSPVT 150 +Q + D + + E + LI AG V +Q + + F V Sbjct: 38 RQTGLDISDEKSVYHYFETIGAFDHLIVTAGSYAPAGKVVDVEVTQAKYAFDTKFWGAVL 97 Query: 151 MTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTE 210 +Y+ K SG +R + N V +A AA+ T+ Sbjct: 98 AAKHGARYL-KQGGSITLTSGMLSRKVVANT--------------YVKAAINAAIEATTK 142 Query: 211 VLAAEMEPRNIRCFTISPGLVKGT---DMIQNLPVEAKEMLERTIGASGTSAPAEIAEEV 267 VLA E+ P IR ISPGL K M + + + + ++IA Sbjct: 143 VLAKELAP--IRVNAISPGLTKTEAYKGMNADDRDAMYQRTQSHLPVGKVGEASDIAMAY 200 Query: 268 WS 269 Sbjct: 201 LF 202 >5TQV-A nrPDB Length = 233 Score = 55.3 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 36/229 (15%), Positives = 78/229 (34%), Gaps = 52/229 (22%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++ GA+RG+G+ ++ + G + I S+ + Q + A+ + Sbjct: 13 LIVGASRGLGREFVRQYQRDGWNVIATARDDASLAALRALGAHAHALDITQPEQIAALGW 72 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 K LD ++++ + Sbjct: 73 KLDGERLDVA--------------------------------------VVVSGVYGPRTE 94 Query: 128 LSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS 187 + +M+ N P+ + I + + ++ +S + + SI + Sbjct: 95 GVETIASDDFDTVMHTNVRGPMQLLPILLPLVEDARGVLAVVSSR--------MGSISEA 146 Query: 188 GKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDM 236 G +Y ASKAAL+ + + ++ R+ C ++ PG V+ TDM Sbjct: 147 --TGTTGW-LYRASKAALNDVLRIAS--LQTRHAACISLHPGWVR-TDM 189 >4ALL-A nrPDB Length = 277 Score = 55.3 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 40/262 (15%), Positives = 78/262 (29%), Gaps = 45/262 (17%) Query: 14 RGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHW 73 R I + + L Q G + + S + QL ++ Q + D Sbjct: 39 RSIAFGVAKVLDQLGAKLVFTYRKERSRKELEKLLEQLNQPEAHLYQIDVQSD------- 91 Query: 74 LDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTT 133 ++ F+ K N Y ++ + T+ Sbjct: 92 -------------------EEVINGFEQIGKDVGNIDGVYHSIAFANMEDLR-GRFSETS 131 Query: 134 ASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVP 193 +++ S + + K M +IV ++ G+ V Sbjct: 132 REGFLLAQDISSYSLTIVAHEAKKLM-------------PEGGSIV--ATTYLGGEFAVQ 176 Query: 194 GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--EAKEMLERT 251 +V +KA+L + LA ++ P NIR IS G ++ T + + + +E Sbjct: 177 NYNVMGVAKASLEANVKYLALDLGPDNIRVNAISAGPIR-TLSAKGVGGFNTILKEIEER 235 Query: 252 IGASGTSAPAEIAEEVWSLYSR 273 E+ + L S Sbjct: 236 APLKRNVDQVEVGKTAAYLLSD 257 >4ZJU-A nrPDB Length = 275 Score = 55.3 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 39/263 (14%), Positives = 76/263 (28%), Gaps = 47/263 (17%) Query: 16 IGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLD 75 I I Q L ++G ++ +R D Q G C +A+D + + + Sbjct: 30 IAYGIAQALHREGAELAFTYPNEKLKKRV--DEFAEQFGSKLVFPCDVAVDAEIDNAFAE 87 Query: 76 YESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTAS 135 + +D + ++ + L + T Sbjct: 88 L-------------------AKHWDGVDGVVHSIGFAPAHTL--------DGDFTDVTDR 120 Query: 136 Q-IQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPG 194 + +++ S V M + Q L+ Q + + P Sbjct: 121 DGFKIAHDISAYSFVAMARAAKPLLQARQGCLLTLTYQGSERVM--------------PN 166 Query: 195 TSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--EAKEMLERTI 252 +V +KA+L LA+ + IR IS G ++ T + + + E+ Sbjct: 167 YNVMGMAKASLEAGVRYLASSLGVDGIRVNAISAGPIR-TLAASGIKSFRKMLDANEKVA 225 Query: 253 GASGTSAPAEIAEEVWSLYSRTA 275 E+ L S A Sbjct: 226 PLKRNVTIEEVGNAALFLCSPWA 248 >1ENP-A nrPDB Length = 312 Score = 54.5 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 47/277 (16%), Positives = 90/277 (32%), Gaps = 24/277 (8%) Query: 7 AIVTGATR--GIGKAICQKLFQKGLSCIILG-STKESIERTAIDRGQLQSGLSYQRQCAI 63 A + G G G A+ + L G ++ +I T++ RG+ + Sbjct: 21 AFIAGIADDNGYGWAVAKSLAAAGAEILVGTWVPALNIFETSLRRGKFDQSRVLPDGSLM 80 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINC--A 121 I + D E K + + + +++L++ Sbjct: 81 EIKKVYPLDAVFDNPEDVPEDVKANKRYAGSSNWTVQEAAECVR-QDFGSIDILVHSLAN 139 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 G + T+ ++ + S V++ + + M + +++ Sbjct: 140 GPEVSKPLLETSRKGYLAAISASSYSFVSLLSHFLPIM-------------NPGGASISL 186 Query: 182 SSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPR-NIRCFTISPGLVKGTDMIQNL 240 + I + G + S++KAAL T VLA E + NIR TIS G + G+ + + Sbjct: 187 TYIASERIIPGYGGGM-SSAKAALESDTRVLAFEAGRKQNIRVNTISAGPL-GSRAAKAI 244 Query: 241 P--VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 E T E+ L S A Sbjct: 245 GFIDTMIEYSYNNAPIQKTLTADEVGNAAAFLVSPLA 281 >5CFZ-A nrPDB Length = 305 Score = 54.5 bits (129), Expect = 6e-08, Method: Composition-based stats. Identities = 44/270 (16%), Positives = 73/270 (27%), Gaps = 48/270 (17%) Query: 8 IVTGATR--GIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +VTG I I Q + ++G + R QL S + Q A Sbjct: 53 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA--- 109 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 E F + + K+ ++ +N Sbjct: 110 -----------EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDY---VN------ 149 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 T + +++ S V M C + M+ LS A I Sbjct: 150 -----AVTREGFKIAHDISSYSFVAMAKAC-RSMLNPGSALLTLSYLGAERAI------- 196 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--E 243 P +V +KA+L +A M P +R IS G ++ T + + Sbjct: 197 -------PNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIR-TLAASGIKDFRK 248 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 E T ++ L S Sbjct: 249 MLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 278 >1FJH-A nrPDB Length = 257 Score = 54.1 bits (128), Expect = 7e-08, Method: Composition-based stats. Identities = 45/289 (15%), Positives = 92/289 (31%), Gaps = 72/289 (24%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 + + +++G GIG A + L G + Sbjct: 1 MSIIVISGCATGIGAATRKVLEAAGHQIV------------------------------- 29 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 +D + I KQ + + C+K ++ L+ CAGL Sbjct: 30 ---------GIDIRDAEVIADLSTAEGRKQAIADVLAKCSK--------GMDGLVLCAGL 72 Query: 124 TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVN--- 180 ++ + ++++VN+ + + + + K + + A + Sbjct: 73 GPQTKVLG-------NVVSVNYFGATELMDAFLPALKKGHQPAAVVISSVASAHLAFDKN 125 Query: 181 -ISSILHSGKMKVP-----------GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISP 228 ++ L +G+ G Y+ SK AL+ AA +R TI+P Sbjct: 126 PLALALEAGEEAKARAIVEHAGEQGGNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAP 185 Query: 229 GLVKGTDMIQNL-PVEAKEMLERTI-GASGTSAPAEIAEEVWSLYSRTA 275 G + + L E + + + + P+E+A + L S A Sbjct: 186 GATETPLLQAGLQDPRYGESIAKFVPPMGRRAEPSEMASVIAFLMSPAA 234 >5KOI-A nrPDB Length = 293 Score = 53.7 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 38/262 (14%), Positives = 73/262 (27%), Gaps = 56/262 (21%) Query: 19 AICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYES 78 I ++L +G +R Q+ S D+ Sbjct: 45 GIAKQLAAQGAELAFTYQGDALGKRVKPLAEQVGS---------------------DFVL 83 Query: 79 YDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVR-----TT 133 +E + ++ + ++ L++ G + ++ TT Sbjct: 84 PCDVEDIATVDAVFEEIEKKW------------GGLDFLVHAIGFSDKTELKGRYADVTT 131 Query: 134 ASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVP 193 M ++ S + K M +I+ ++ +P Sbjct: 132 RENFSRTMVISAYSFTEVAQRAEKLMK-------------DGGSILTLT--YGGSTRTIP 176 Query: 194 GTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--EAKEMLERT 251 +V +KAAL LAA+ P+ IR IS G V+ T + R Sbjct: 177 NYNVMGVAKAALEAMVRYLAADYGPQGIRVNAISAGPVR-TLAGAGIGDARAIFSYQRRN 235 Query: 252 IGASGTSAPAEIAEEVWSLYSR 273 T ++ + L S Sbjct: 236 SPLRRTVDIDDVGKSAVYLLSD 257 >3GRK-A nrPDB Length = 293 Score = 53.7 bits (127), Expect = 7e-08, Method: Composition-based stats. Identities = 44/269 (16%), Positives = 89/269 (33%), Gaps = 33/269 (12%) Query: 13 TRGIGKAICQKLFQKGLSCIILGSTKESIER--TAIDRGQLQSGLSYQRQCAIAIDFKKW 70 T+G G Q +G +ILG A + + L++ Q + Sbjct: 16 TQGPGSMTAQSGLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEP 75 Query: 71 PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE---- 126 G D + + TL ++ ++ L++ G + + Sbjct: 76 LAEELGAFVAGHCDVADAASIDAVFETL---------EKKWGKLDFLVHAIGFSDKDELT 126 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T+ + + M ++ S ++ K M + +I+ ++ + Sbjct: 127 GRYIDTSEANFTNTMLISVYSLTAVSRRAEKLM-------------ADGGSILTLT--YY 171 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVE--A 244 + +P +V +KAAL + LA ++ P+NIR IS G +K T + Sbjct: 172 GAEKVMPNYNVMGVAKAALEASVKYLAVDLGPQNIRVNAISAGPIK-TLAASGIGDFRYI 230 Query: 245 KEMLERTIGASGTSAPAEIAEEVWSLYSR 273 + E T E+ + S Sbjct: 231 LKWNEYNAPLRRTVTIDEVGDVGLYFLSD 259 >4JQC-A nrPDB Length = 282 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 44/270 (16%), Positives = 73/270 (27%), Gaps = 48/270 (17%) Query: 8 IVTGATR--GIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 +VTG I I Q + ++G + R QL S + Q A Sbjct: 30 LVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSDIVLQCDVA--- 86 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 E F + + K+ ++ +N Sbjct: 87 -----------EDASIDTMFAELGKVWPKFDGFVHSIGFAPGDQLDGDY---VN------ 126 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 T + +++ S V M C + M+ LS A I Sbjct: 127 -----AVTREGFKIAHDISSYSFVAMAKAC-RSMLNPGSALLTLSYLGAERAI------- 173 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV--E 243 P +V +KA+L +A M P +R IS G ++ T + + Sbjct: 174 -------PNYNVMGLAKASLEANVRYMANAMGPEGVRVNAISAGPIR-TLAASGIKDFRK 225 Query: 244 AKEMLERTIGASGTSAPAEIAEEVWSLYSR 273 E T ++ L S Sbjct: 226 MLAHCEAVTPIRRTVTIEDVGNSAAFLCSD 255 >4NR0-A nrPDB Length = 273 Score = 52.2 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 31/273 (11%), Positives = 71/273 (26%), Gaps = 45/273 (16%) Query: 7 AIVTGATR--GIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 A++ G I I + ++G + R S C +A Sbjct: 9 ALIVGVASKLSIASGIAAAMHREGAELAFTYQNDKLRGRVEEFASGWGSRPELCFPCDVA 68 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 D ++ ++ L + ++++++ G Sbjct: 69 ----------------------DDSQIEAVFAAL---------GKHWDGLDIIVHSVGFA 97 Query: 125 QESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + + Y + + + +++ +S Sbjct: 98 PGDQL----DGDFTAVT---TREGFRIAHDISAYSFIALAKAGREMMKGRNGSLLTLS-- 148 Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPV-- 242 + +P +V +KA+L LA + R +S G ++ T + Sbjct: 149 YLGAERTMPNYNVMGMAKASLEAGVRYLAGSLGAEGTRVNAVSAGPIR-TLAASGIKSFR 207 Query: 243 EAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + ER E+ L S A Sbjct: 208 KMLAANERQTPLRRNVTIEEVGNAGAFLCSDLA 240 >4M89-A nrPDB Length = 261 Score = 51.0 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 40/270 (14%), Positives = 77/270 (28%), Gaps = 47/270 (17%) Query: 8 IVTG--ATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 ++TG + R I I + ++G + ER +L S L ++ A Sbjct: 10 LITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSELVFRCDVA--- 66 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 + Q ++ L + ++ L++ G Sbjct: 67 ---------------------SDDEINQVFADL---------GKHWDGLDGLVHSIGFAP 96 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + + D ++ + Y + + + + IV +S Sbjct: 97 KEAL----SGDFLDSIS---REAFNTAHEISAYSLPALAKAARPMMRGRNSAIVALS--Y 147 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 +P +V +KA+L AA + IRC IS G +K T + K Sbjct: 148 LGAVRAIPNYNVMGMAKASLEAGIRFTAACLGKEGIRCNGISAGPIK-TLAASGIADFGK 206 Query: 246 --EMLERTIGASGTSAPAEIAEEVWSLYSR 273 + E+ L S Sbjct: 207 LLGHVAAHNPLRRNVTIEEVGNTAAFLLSD 236 >4NK4-A nrPDB Length = 301 Score = 50.3 bits (118), Expect = 9e-07, Method: Composition-based stats. Identities = 37/258 (14%), Positives = 72/258 (27%), Gaps = 45/258 (17%) Query: 16 IGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLD 75 I I + L G + +R + A+ +D D Sbjct: 55 IAWGIAKVLHSAGAQLAFSYQGESIGKRL--------------KPLALTVDS-------D 93 Query: 76 YESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTAS 135 + +E L ++ ++ + ++ N L T+ Sbjct: 94 FMIPCNVEDPSSMDLLFERIKERWETLDFVVHSIAFSDKNEL--------RGPYYNTSRD 145 Query: 136 QIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKVPGT 195 + +S + T I ++ + P I+ VP Sbjct: 146 NF---IQTMLVSCFSFTEIV----RRAAQLMPHGGAM--------ITLTYGGSMRVVPNY 190 Query: 196 SVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG-TDMIQNLPVEAKEMLERTIGA 254 + + +K+AL T+ LA + NIR IS G V+ + + + Sbjct: 191 NAMAPAKSALESSTKYLACDYGGMNIRINAISAGPVRTLAGASISNGRDIAAWSKENSPL 250 Query: 255 SGTSAPAEIAEEVWSLYS 272 T + +I L S Sbjct: 251 KRTVSLEDIGNSALYLLS 268 >2PTG-A nrPDB Length = 319 Score = 50.3 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 44/296 (14%), Positives = 90/296 (30%), Gaps = 39/296 (13%) Query: 5 PVAIVTGA--TRGIGKAICQKLFQKGLSCI------ILGSTKESIERTAIDRGQLQSGLS 56 A V G + G G AIC+ L G + + K+ +E + ++ + Sbjct: 10 KTAFVAGVADSNGYGWAICKLLRAAGARVLVGTWPPVYSIFKKGLESSRFEQDSFYAQEP 69 Query: 57 YQRQCAIAIDF-------KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNE 109 + A A + K +P +++ + + Sbjct: 70 SSKVAAEAAEKPVDLVFDKIYPLDAVFDTPQDVPPEVSSNKRYAGVGGFTISEVAEAVRA 129 Query: 110 RRYYVNLLINC--AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWP 167 +++L++ G ++T+ ++ + S V++ + M + Sbjct: 130 DVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLLQHFLPLMKE------ 183 Query: 168 ELSGQSARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEP-RNIRCFTI 226 + + +S I + G + S++KAAL LA E R +R I Sbjct: 184 -------GGSALALSYIASEKVIPGYGGGM-SSAKAALESDCRTLAFEAGRARAVRVNCI 235 Query: 227 SPGLVKGTDMIQNLPVEAKEMLERTI-------GASGTSAPAEIAEEVWSLYSRTA 275 S G +K K ++ I ++ L S A Sbjct: 236 SAGPLKSRAASAIGKAGDKTFIDLAIDYSEANAPLQKELESDDVGRAALFLLSPLA 291 >5I9N-A nrPDB Length = 276 Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 40/272 (14%), Positives = 73/272 (26%), Gaps = 48/272 (17%) Query: 8 IVTG--ATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 ++TG + R I I + ++G +R + S L + A Sbjct: 10 LLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSELVFPCDVA--- 66 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D + +++L + AG Sbjct: 67 ---------------------DDAQIDALFASLKTHWDSLDGLVHSIGFAPREAIAGDFL 105 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 + L T + +++ S + + M+ LS A I Sbjct: 106 DGL----TRENFRIAHDISAYSFPALAKAALP-MLSDDASLLTLSYLGAERAI------- 153 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 P + +KAAL LA + + +R IS G +K T + K Sbjct: 154 -------PNYNTMGLAKAALEASVRYLAVSLGAKGVRVNAISAGPIK-TLAASGIKSFGK 205 Query: 246 --EMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + +E ++ L S A Sbjct: 206 ILDFVESNSPLKRNVTIEQVGNAGAFLLSDLA 237 >4J3F-A nrPDB Length = 280 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 27/271 (9%), Positives = 77/271 (28%), Gaps = 46/271 (16%) Query: 8 IVTG--ATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 ++TG + + I I + + ++G + +++ + + C + Sbjct: 30 LITGLLSNKSIAYGIAKAMHREGAELAFTYVGQFKDR---VEKLCAEFNPAAVLPCDVIS 86 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQ 125 D + +++ ++D + ++ + L Sbjct: 87 DQEIKDLFVELGK-------------------VWDGLDAIVHSIAFAPRDQL-------- 119 Query: 126 ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSIL 185 E + + ++ + Y + + ++ ++V ++ I Sbjct: 120 EGNFIDCVTRE-----------GFSIAHDISAYSFAALAKEGRSMMKNRNASMVALTYI- 167 Query: 186 HSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAK 245 + +P + +KA+L A + I+ +S G +K + Sbjct: 168 -GAEKAMPSYNTMGVAKASLEATVRYTALALGEDGIKVNAVSAGPIKTLAASGISNFKKM 226 Query: 246 EMLERTI-GASGTSAPAEIAEEVWSLYSRTA 275 + E+ V L S A Sbjct: 227 LDYNAMVSPLKKNVDIMEVGNTVAFLCSDMA 257 >3F4B-A nrPDB Length = 323 Score = 44.9 bits (104), Expect = 3e-05, Method: Composition-based stats. Identities = 46/299 (15%), Positives = 99/299 (33%), Gaps = 54/299 (18%) Query: 11 GATRGIGKAICQKLFQKGLSCI------ILGSTKESIERTAIDRGQLQSGLSYQRQCAIA 64 G + G G I ++L ++ + I + +++E D+ + + + +R + Sbjct: 16 GDSNGYGWGIAKELSKRNVKVIFGVWPPVYNIFIKNLESGKFDKDMIINNDNSKRMQIL- 74 Query: 65 IDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLI---NCA 121 P +++YD I+ + +++L+ Sbjct: 75 ---DVLPLDAGFDNYDDIDEDTKNNKRYNNLKNYSIEEVANLIYNKYGKISMLVHSLAN- 130 Query: 122 GLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNI 181 G + + T+ D ++ + S +++ K+M ++ ++V Sbjct: 131 GREVQKSLLDTSRDGYLDAISKSSYSLISLCKHFCKFM-------------NSGGSVV-- 175 Query: 182 SSILHSGKMKVPGTSV-YSASKAALSRFTEVLAAEMEPR-NIRCFTISPGLVKGTDMIQ- 238 S + + VPG S++KAAL T VLA + + NIR TIS G +K Sbjct: 176 SLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINTISAGPLKSRAATAI 235 Query: 239 ----------------------NLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + A + E+ ++ L S+ + Sbjct: 236 NKFNNNQKNNMNSSGETDKQNYSFIDYAIDYSEKYAPLKKKLLSTDVGSVASFLLSKES 294 >3SLK-A nrPDB Length = 795 Score = 44.5 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 36/245 (14%), Positives = 86/245 (35%), Gaps = 53/245 (21%) Query: 8 IVTGATRGIGKAICQKLF-QKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 +VTG T +G + + L ++G+ ++L S + A + + Sbjct: 534 LVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAE---------------LVAQ 578 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + + ++ D DR L + +++ D + +++ AG+ + Sbjct: 579 LTAYGAEVSLQACD----VADRETLAKVLASIPDEH----------PLTAVVHAAGVLDD 624 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 +S T ++ ++ + + + +V SS+ Sbjct: 625 GVSESLTVERLDQVLRPKVDGARNLLELIDPDV-----------------ALVLFSSV-- 665 Query: 187 SGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQNLPVEAKE 246 SG + G Y+A+ + F + LA + + R + +++ G M L ++ Sbjct: 666 SGVLGSGGQGNYAAA----NSFLDALAQQRQSRGLPTRSLAWGPWAEHGMASTLREAEQD 721 Query: 247 MLERT 251 L R+ Sbjct: 722 RLARS 726 >3K2E-A nrPDB Length = 296 Score = 43.7 bits (101), Expect = 8e-05, Method: Composition-based stats. Identities = 24/109 (22%), Positives = 36/109 (33%), Gaps = 7/109 (6%) Query: 171 GQSARPTIVNISSILHSGKMK----VPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTI 226 A P + N SIL VP +V KAAL + LA ++ + IR I Sbjct: 151 ASKAEPLMTNGGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQIRVNAI 210 Query: 227 SPGLVKGTDMIQNLPVEAKEMLERTI--GASGTSAPAEIAEEVWSLYSR 273 S G V+ T + + + ++ L S Sbjct: 211 SAGPVR-TLASSGISDFHYILTWNKYNSPLRRNTTLDDVGGAALYLLSD 258 >2NTV-A nrPDB Length = 268 Score = 41.4 bits (95), Expect = 4e-04, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 34/107 (31%), Gaps = 15/107 (14%) Query: 182 SSILHSGKMKVPGTSVY---SASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 SI+ Y + +K+AL +A E +R ++ G ++ M Sbjct: 141 GSIVGMDFDPTRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSA 200 Query: 239 NLPVE-----------AKEMLERTIGAS-GTSAPAEIAEEVWSLYSR 273 + +E ++ P +A+ V +L S Sbjct: 201 IVGGAFGEEAGAQMQLLEEGWDQRAPIGWNMKDPTPVAKTVCALLSE 247 >2PD3-A nrPDB Length = 275 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 45/130 (34%), Gaps = 27/130 (20%) Query: 112 YYVNLLINCAGLTQ----ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWP 167 ++ +++ E + T+ S M ++ S + +TN + Sbjct: 83 GSLDFIVHSVAFAPKEALEGSLLETSKSAFNTAMEISVYSLIELTNTLKPLLN------- 135 Query: 168 ELSGQSARPTIVNISSILHSGKMKVPGT-SVYSA---SKAALSRFTEVLAAEMEPRNIRC 223 N +S+L + + Y+ +KAAL LA ++ +IR Sbjct: 136 ------------NGASVLTLSYLGSTKYMAHYNVMGLAKAALESAVRYLAVDLGKHHIRV 183 Query: 224 FTISPGLVKG 233 +S G ++ Sbjct: 184 NALSAGPIRT 193 >3ENK-A nrPDB Length = 341 Score = 41.0 bits (94), Expect = 5e-04, Method: Composition-based stats. Identities = 13/100 (13%), Positives = 28/100 (28%), Gaps = 1/100 (1%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M +VTG IG +L G +I + S ++ + Sbjct: 2 MSTKGTILVTGGAGYIGSHTAVELLAHGYDVVIADNLVNSKREAIARIEKITGKTPAFHE 61 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFD 100 ++ D + D +F + + + + Sbjct: 62 TDVS-DERALARIFDAHPITAAIHFAALKAVGESVAKPIE 100 >2O2Y-A nrPDB Length = 349 Score = 40.6 bits (93), Expect = 7e-04, Method: Composition-based stats. Identities = 41/229 (17%), Positives = 78/229 (34%), Gaps = 23/229 (10%) Query: 11 GATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID-FKK 69 G T G G I ++L ++ + I G + + ++ Sbjct: 23 GDTNGYGWGIAKELSKRNVKI-IFGIWPPVYNIFMKNYKNGKFDNDMIIDKDKKMNILDM 81 Query: 70 WPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLI---NCAGLTQE 126 P +++ + I+ +++ +N+L+ A Q Sbjct: 82 LPFDASFDTANDIDEETKNNKRYNMLQNYTIEDVANLIHQKYGKINMLVHSLANAKEVQ- 140 Query: 127 SLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILH 186 + T+ D ++ + S +++ + M +I+ S H Sbjct: 141 KDLLNTSRKGYLDALSKSSYSLISLCKYFVNIMKPQS-------------SII--SLTYH 185 Query: 187 SGKMKVPGTSV-YSASKAALSRFTEVLAAEMEP-RNIRCFTISPGLVKG 233 + + VPG S++KAAL T VLA + NIR TIS G +K Sbjct: 186 ASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRINTISAGPLKS 234 >4OYR-A nrPDB Length = 289 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 35/107 (32%), Gaps = 15/107 (14%) Query: 182 SSILHSGKMKVPGTSVY---SASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQ 238 SI+ Y + +K+AL +A E +R ++ G ++ M Sbjct: 162 GSIVGMDFDPSRAMPAYNWMTVAKSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSA 221 Query: 239 ----NLPVEA-------KEMLERTIGAS-GTSAPAEIAEEVWSLYSR 273 L EA +E ++ +A+ V +L S Sbjct: 222 IVGGALGEEAGAQIQLLEEGWDQRAPIGWNMKDATPVAKTVCALLSD 268 >4LIS-A nrPDB Length = 371 Score = 39.9 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 13/93 (13%), Positives = 28/93 (30%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG T IG L + G ++ + S + + Q + + Sbjct: 7 LVTGGTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEA 66 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFD 100 + + D + +F + + D Sbjct: 67 AFDKVFEAHPDIDSVIHFAALKAVGESGEKPLD 99 >1Z45-A nrPDB Length = 699 Score = 37.9 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 28/91 (30%), Gaps = 1/91 (1%) Query: 3 YLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 + +VTG IG +L + G C++ + S + L + Sbjct: 10 TSKIVLVTGGAGYIGSHTVVELIENGYDCVVADNLSNSTYDSVARLEVLTKHHIPFYEVD 69 Query: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQ 93 + D K D + +F + + Sbjct: 70 L-CDRKGLEKVFKEYKIDSVIHFAGLKAVGE 99 >1UDA-A nrPDB Length = 338 Score = 36.0 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 34/101 (33%), Gaps = 4/101 (3%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG + IG C +L Q G IIL + S +L + + D Sbjct: 4 LVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGG----KHPTFVEGDI 59 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNN 108 + + I+ LK ++ P + NN Sbjct: 60 RNEALMTEILHDHAIDTVIHFAGLKAVGESVQKPLEYYDNN 100 >6ACQ-A nrPDB Length = 302 Score = 33.7 bits (75), Expect = 0.079, Method: Composition-based stats. Identities = 14/99 (14%), Positives = 27/99 (27%), Gaps = 5/99 (5%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 H V ++ +G I Q KG ++ E ++R + LS + Sbjct: 20 HMKKVCVI--GAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDR---GLDFINKNLSKLVKK 74 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFD 100 + K + D + + D Sbjct: 75 GKIEEATKVEILTRISGTVDLNMAADCDLVIEAAVERMD 113 >3NJ4-A nrPDB Length = 435 Score = 33.7 bits (75), Expect = 0.092, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 37/116 (31%), Gaps = 4/116 (3%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA+V G +GK Q L G II + + A++ ++ + Sbjct: 213 MIAGKVAVVAGYGD-VGKGCAQALRGFGARVIITEIDPINALQAAMEGYEV---TTMDEA 268 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNL 116 C F +D E KD + + KW N VN+ Sbjct: 269 CQEGNIFVTTTGCIDIILGRHFEQMKDDAIVCNIGHFDVEIDVKWLNENAVEKVNI 324 >5N2I-A nrPDB Length = 232 Score = 33.7 bits (75), Expect = 0.095, Method: Composition-based stats. Identities = 9/42 (21%), Positives = 18/42 (42%) Query: 9 VTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQ 50 V G T G+ + ++ G I+ + E + A + G+ Sbjct: 24 VLGGTGDQGRGLARRFAMAGHEVILGSRSAERAQAVAAELGE 65 >2C20-A nrPDB Length = 330 Score = 32.9 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 27/187 (14%), Positives = 62/187 (33%), Gaps = 12/187 (6%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++ G IG +KL +GLS +++ + + E + + +G + + Sbjct: 5 LICGGAGYIGSHAVKKLVDEGLSVVVVDNLQTGHEDAITEGAKFYNGDLRDKAFLRDVFT 64 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 ++ + + + D + PL Q Y+ + V+ I S Sbjct: 65 QENIEAVMHFAADSLVGVSMEKPL-QYYNNNVYGALCLLEVMDEFKVDKFI------FSS 117 Query: 128 LSVRTTASQIQDIMN---VNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSI 184 + + I N + T + I+ M+ + L + R N++ Sbjct: 118 TAATYGEVDVDLITEETMTNPTNTYGETKLAIEKMLHWYSQASNLRYKIFRY--FNVAGA 175 Query: 185 LHSGKMK 191 +G + Sbjct: 176 TPNGIIG 182 >1O89-A nrPDB Length = 345 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 17/35 (48%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIE 42 +VTGA+ G+G L + G + + + + E Sbjct: 172 VVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHE 206 >1DIR-A nrPDB Length = 241 Score = 32.9 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 11/57 (19%), Positives = 19/57 (33%), Gaps = 3/57 (5%) Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLA--AEMEPRNIRCFTISPGLVKGTDMIQN 239 + PG Y +K A+ + + LA P + P + T M + Sbjct: 134 AKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLP-VTLDTPMNRK 189 >5GXF-A nrPDB Length = 330 Score = 32.5 bits (72), Expect = 0.22, Method: Composition-based stats. Identities = 18/137 (13%), Positives = 40/137 (29%), Gaps = 2/137 (1%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIE-RTAIDRGQLQSGLSYQRQCAI 63 PV +VTGA G+G L G + E+ + T++ Q+ + Sbjct: 152 PV-LVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGATQIVARDEINETVKR 210 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 ++ + W +D + + + + ++ +N G+ Sbjct: 211 PLESEIWAGCVDAVGGAMLARVLGQMKYGASVAAVGLAGGAGLPATVIPFLLRGVNLLGI 270 Query: 124 TQESLSVRTTASQIQDI 140 + I Sbjct: 271 DSVMQPYANRLRAWERI 287 >4K28-A nrPDB Length = 269 Score = 31.8 bits (70), Expect = 0.30, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 36/116 (31%), Gaps = 7/116 (6%) Query: 7 AIVTGATRGIGKAICQKLFQKG-LSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 A+V G G+G AI L + G S + + + G GL+ Q + Sbjct: 128 ALVIGCG-GVGSAIAYALAEAGIASITLCDPSTARMGAVCELLGNGFPGLTVSTQFSGLE 186 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 DF + E PL P ++ + L+N A Sbjct: 187 DFDLVANASPVGMGTRAEL-----PLSAALLATLQPDTLVADVVTSPEITPLLNRA 237 >4J6F-A nrPDB Length = 382 Score = 31.8 bits (70), Expect = 0.32, Method: Composition-based stats. Identities = 17/71 (23%), Positives = 28/71 (39%), Gaps = 2/71 (2%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTGA+ G+G AI Q +G + + E +D G Q A A++ Sbjct: 211 LVTGASGGVGSAIIQLARARGA--VPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAEAVEA 268 Query: 68 KKWPHWLDYES 78 +D + Sbjct: 269 ASGGRPIDVVA 279 >2Q1W-A nrPDB Length = 333 Score = 31.8 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 33/121 (27%), Gaps = 10/121 (8%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 H V +TG IG I + L ++G + + + D L + Sbjct: 20 HMKKV-FITGICGQIGSHIAELLLERGDKVVGIDNFATGRREHLKDHPNLTFV-----EG 73 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 +IA D + + Y+ C SN + N Sbjct: 74 SIADHALVNQLIGDLQPDAVVHTAASYKDPDDWYNDTLTNCVGGSNVVQAAKK----NNV 129 Query: 122 G 122 G Sbjct: 130 G 130 >6BWL-A nrPDB Length = 328 Score = 31.4 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 25/192 (13%), Positives = 53/192 (27%), Gaps = 20/192 (10%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTG IG+ + ++L Q IL + S TA Q D Sbjct: 4 LVTGGAGFIGRWVVKRLLQDKHEVWILDNLANST--TANITEFAHDLNLKQCIQGDIKDK 61 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLF-----DPCNKWSNNERRYYVNL-LI--- 118 K + S+D + ++ D ++ E+ ++ ++ Sbjct: 62 KLVAQLFENNSFDLCYHLAASINVQDSIDDARATFENDTIGTFNLLEQCLNYDVKMVFMS 121 Query: 119 ---------NCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPEL 169 N G+++ + I N + +++ + Sbjct: 122 TCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLSYYYAYKLPVVVIRPFNTYGPF 181 Query: 170 SGQSARPTIVNI 181 +V I Sbjct: 182 QKTGGEGGVVAI 193 >1JAY-A nrPDB Length = 212 Score = 31.0 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 15/86 (17%), Positives = 29/86 (33%), Gaps = 1/86 (1%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA++ G T +GK + +L G ++ +E E A + ++ S Sbjct: 3 VALL-GGTGNLGKGLALRLATLGHEIVVGSRREEKAEAKAAEYRRIAGDASITGMKNEDA 61 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPL 91 L I+ +D + Sbjct: 62 AEACDIAVLTIPWEHAIDTARDLKNI 87 >3VPX-A nrPDB Length = 364 Score = 31.0 bits (68), Expect = 0.61, Method: Composition-based stats. Identities = 20/125 (16%), Positives = 40/125 (32%), Gaps = 3/125 (2%) Query: 10 TGATRGIG---KAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAID 66 T A +G+G A+C+ L ++G II +E+++R G G++ I Sbjct: 175 TVAVQGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGINEIYSQEADIF 234 Query: 67 FKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQE 126 + + K + Y + +IN G+ Sbjct: 235 APCALGAIINDETIPQLKAKVIAGSANNQLKETRHGDLIHEMGIVYAPDYVINSGGVINV 294 Query: 127 SLSVR 131 + + Sbjct: 295 ADELD 299 >4UUP-A nrPDB Length = 341 Score = 31.0 bits (68), Expect = 0.65, Method: Composition-based stats. Identities = 18/120 (15%), Positives = 42/120 (35%), Gaps = 9/120 (7%) Query: 8 IVTGATRGIGKAICQKLFQK---GLSCIILGSTKESIERTAIDRGQLQ------SGLSYQ 58 ++TGA IG A+ ++ + G ++L + A++ ++ L+ Sbjct: 8 LITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAGV 67 Query: 59 RQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLI 118 + K + +R L +K + +F K + + V +L+ Sbjct: 68 VATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVKVLV 127 >3F6S-A nrPDB Length = 148 Score = 30.6 bits (67), Expect = 0.73, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 31/101 (30%), Gaps = 4/101 (3%) Query: 3 YLPVAIVTGATRGIGKAICQKL----FQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQ 58 V IV G++ G ++I QKL G +L + S E A + G S Sbjct: 1 MSKVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLADGYDAVLFGCSAW 60 Query: 59 RQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLF 99 + + + +++ + F Sbjct: 61 GMEDLEMQDDFLSLFEEFDRIGLAGRKVAAFASGDQEYEHF 101 >1OOE-A nrPDB Length = 236 Score = 30.6 bits (67), Expect = 0.78, Method: Composition-based stats. Identities = 8/29 (27%), Positives = 11/29 (37%) Query: 185 LHSGKMKVPGTSVYSASKAALSRFTEVLA 213 + P Y +KAA+ T LA Sbjct: 130 AAAAMGPTPSMIGYGMAKAAVHHLTSSLA 158 >1I3M-A nrPDB Length = 348 Score = 30.6 bits (67), Expect = 0.78, Method: Composition-based stats. Identities = 7/33 (21%), Positives = 15/33 (45%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKES 40 +VTG IG +L + G +++ + + Sbjct: 6 LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNA 38 >3PEF-A nrPDB Length = 287 Score = 30.6 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 29/261 (11%), Positives = 72/261 (27%), Gaps = 16/261 (6%) Query: 15 GI-GKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGL-SYQRQCAIAIDFKKWPH 72 GI G A+ + L + G S I + E E A + + C + P Sbjct: 10 GIMGSAMAKNLVKAGCSVTIWNRSPEKAEELAALGAERAATPCEVVESCPVTFAMLADPA 69 Query: 73 WLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRT 132 + + + + ++ G E+ + Sbjct: 70 AAEEVCFGKHGVLEGIGEGRGYVDMSTVDPATSQRIGVA-----VVAKGGRFLEAPVSGS 124 Query: 133 TASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHSGKMKV 192 + + + + + K ++ L + + +++ G M Sbjct: 125 KKPAEDGTLIILAAGDRNLYDEAMPGFEKMGKKIIHLGDVGKGAEMKLVVNMVMGGMMAC 184 Query: 193 PGTSVYSASKAALSRFTEVLAAEMEPRNIRCF---TISPGLVKGTDMIQNLPVE-AKEML 248 + KA L+ T+ + ++ + GL++ + P++ ++ L Sbjct: 185 FCEGLALGEKAGLA--TDAI-LDVIGAGAMANPMFALKGGLIRDRNFAPAFPLKHMQKDL 241 Query: 249 ERTIGAS-GTSAPAEIAEEVW 268 + P +A Sbjct: 242 RLAVALGDRVGQP-LVASAAA 261 >2NNL-D nrPDB Length = 337 Score = 30.6 bits (67), Expect = 0.84, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 18/36 (50%) Query: 9 VTGATRGIGKAICQKLFQKGLSCIILGSTKESIERT 44 VTGA+ IG + +L ++G + ++++ Sbjct: 10 VTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKV 45 >5K1S-A nrPDB Length = 362 Score = 30.2 bits (66), Expect = 0.92, Method: Composition-based stats. Identities = 25/177 (14%), Positives = 52/177 (29%), Gaps = 13/177 (7%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 ++TGA+ G+G + Q G I + S++ ++ + R A D Sbjct: 188 LITGASGGVGLSSVQLARLDGARVIAVTSSEAKVQALKEAGADE---VIVSRGLDFASDV 244 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 +K + +E + S N V L GL Sbjct: 245 RKRTQGAGVDV--AVEIVGSATFDQTLKSMAPGGRVVVVGNLESGMVQL---NPGLVIVK 299 Query: 128 LSV-----RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 TT +++ + + + V + ++ + L + +V Sbjct: 300 ELEILGAYATTQAELDEALRLTATGGVRQFVTDAVPLAEAAKAHFRLENREVAGRLV 356 >3PC3-A nrPDB Length = 527 Score = 30.2 bits (66), Expect = 0.94, Method: Composition-based stats. Identities = 20/115 (17%), Positives = 34/115 (29%), Gaps = 2/115 (1%) Query: 10 TGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKK 69 T GIG A+ KG CII+ K S E+ + R + + A Sbjct: 120 TSGNTGIGLAMAC--AVKGYKCIIVMPEKMSNEKVSALRTLGAKIIRTPTEAAYDSPEGL 177 Query: 70 WPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLT 124 + D+ +D + V++++ AG Sbjct: 178 IYVAQQLQRETPNSIVLDQYRNAGNPLAHYDGTAAEILWQLDNKVDMIVVSAGTA 232 >6ILS-A nrPDB Length = 313 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 25/203 (12%), Positives = 53/203 (26%), Gaps = 20/203 (9%) Query: 17 GKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDY 76 GK I + L G + + E T LQS + K WP + Sbjct: 68 GKLIAEALGDDGCGVHLDYVRSVNNEPTGHAVVMLQSDGQNSIIIVGGANMKAWPEIMSD 127 Query: 77 ES----------------YDGIEYFKDRPPLKQKYSTLFD--PCNKWSNNERRYYVNLLI 118 + D I + K + D + NE +++L Sbjct: 128 DDLEIVRNAGIVLLQREIPDSINIQVAKAVKKAGVPVILDVGGMDTPIPNELLDSIDILS 187 Query: 119 NCAGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTI 178 T+ S + I + + + + +I Sbjct: 188 PN--ETELSRLTGMPTETFEQISQAVAKCHKLGVKQVLVKLGSKGSALFIQGEKPIQQSI 245 Query: 179 VNISSILHSGKMKVPGTSVYSAS 201 + + ++ + T+ ++ + Sbjct: 246 IPAAQVVDTTGAGDTFTAAFAVA 268 >1ZZE-A nrPDB Length = 342 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 20/143 (13%), Positives = 39/143 (27%), Gaps = 9/143 (6%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +VTGA + + ++L + G R+A LQ + + Sbjct: 15 LVTGANGFVASHVVEQLLEHGYKV-------RGTARSASKLANLQKRWDAKYPGRF--ET 65 Query: 68 KKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQES 127 L +YD + + + ++ +N L A Sbjct: 66 AVVEDMLKQGAYDEVIKGAAGVAHIASVVSFSNKYDEVVTPAIGGTLNALRAAAATPSVK 125 Query: 128 LSVRTTASQIQDIMNVNFMSPVT 150 V T+++ I N Sbjct: 126 RFVLTSSTVSALIPKPNVEGIYL 148 >3R9I-A nrPDB Length = 260 Score = 29.8 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 17/38 (44%), Gaps = 5/38 (13%) Query: 3 YLPVAIVTGATRGIGK-----AICQKLFQKGLSCIILG 35 + +VT G+GK AI L QKG +++ Sbjct: 1 MARIIVVTSGKGGVGKTTSSAAIATGLAQKGKKTVVID 38 >4KTT-E nrPDB Length = 327 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 18/155 (11%), Positives = 42/155 (27%), Gaps = 18/155 (11%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ------- 60 +VTGAT +G+A+ ++ Q + G + + ++ + Sbjct: 25 LVTGATGLLGRAVHKEFQQNNWHAVGCGFRRARPKFEQVNLLDSNAVHHIIHDFQPHVIV 84 Query: 61 -CAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLF----DPCNKWSNNERRYYVN 115 CA + D S ++ + N + Sbjct: 85 HCAAERRPDVVENQPDAASQLNVDASGNLAKEAAAVGAFLIYISSDYVFDGTNPPYREED 144 Query: 116 LLINCAGLTQESLSVRTTASQIQDIMNVNFMSPVT 150 + +L +T + ++ N + V Sbjct: 145 I------PAPLNLYGKTKLDGEKAVLENNLGAAVL 173 >2CUK-A nrPDB Length = 311 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 17/150 (11%), Positives = 40/150 (26%), Gaps = 13/150 (8%) Query: 12 ATRGIGKAICQKLFQKGLSCIILGSTK----------ESIERTAIDRGQLQSGLSYQRQC 61 IG+A+ ++ G+ + T E + + A + Sbjct: 151 GMGRIGQAVAKRALAFGMRVVYHARTPKPLPYPFLSLEELLKEADVVSLHTPLTPETHRL 210 Query: 62 AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN-- 119 + ++ LF ++ E + L Sbjct: 211 LNRERLFAMKRGAILLNTARGALVDTEALVEALRGHLFGAGLDVTDPEPLPPGHPLYALP 270 Query: 120 CAGLTQE-SLSVRTTASQIQDIMNVNFMSP 148 A +T + RTT ++ ++ N ++ Sbjct: 271 NAVITPHIGSAGRTTRERMAEVAVENLLAV 300 >5OHX-A nrPDB Length = 504 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 16/112 (14%), Positives = 31/112 (27%), Gaps = 2/112 (1%) Query: 10 TGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKK 69 T GIG A+ +G CII+ K S E+ + + + + Sbjct: 105 TSGNTGIGLAMAA--AVRGYKCIIVMPEKMSDEKISTLYALGAKIIRTPTEASWHSPEAH 162 Query: 70 WPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 + D+ +D + ++ L+ A Sbjct: 163 ISVAQKLQKEIPNSIILDQYTNPGNPLAHYDQTAIEIWKQCEGKIDYLVAGA 214 >2Y6O-A nrPDB Length = 291 Score = 29.5 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 12/65 (18%), Positives = 22/65 (33%), Gaps = 8/65 (12%) Query: 214 AEMEPRNIRCFT--ISPGLVKGTDMIQNLPVEAKEMLER---TIGASGTSAPAEIAEEVW 268 ++ RNI + + V M + L + + I +AP IA + Sbjct: 140 RDLAARNILVNSNLVC--KVSDFGMSRVLEDDPEAAYTTRGGKIPI-RWTAPEAIAYRKF 196 Query: 269 SLYSR 273 + S Sbjct: 197 TSASD 201 >2WWR-A nrPDB Length = 330 Score = 29.5 bits (64), Expect = 1.6, Method: Composition-based stats. Identities = 14/104 (13%), Positives = 28/104 (26%), Gaps = 1/104 (0%) Query: 12 ATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA-IAIDFKKW 70 IG+AI ++L G+ + + E A + + S Q I + Sbjct: 162 GLGRIGQAIARRLKPFGVQRFLYTGRQPRPEEAAEFQAEFVSTPELAAQSDFIVVACSLT 221 Query: 71 PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYV 114 P + D + K+ + + Sbjct: 222 PATEGLCNKDFFQKMKETAVFINISRGDVVNQDDLYQALASGKI 265 >3HDH-A nrPDB Length = 302 Score = 29.5 bits (64), Expect = 1.7, Method: Composition-based stats. Identities = 20/150 (13%), Positives = 46/150 (30%), Gaps = 25/150 (16%) Query: 9 VTGATRGI-GKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQR-------- 59 VT G+ G I Q G + +++ T++ + ++ + ++ ++ Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKAG 77 Query: 60 ---------QCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNER 110 + + D H D +E K + L ++ +++N Sbjct: 78 DEFVEKTLSSISTSTDAASVVHSTDLVVEAIVENLKVKSELFKRLDKFAAEHTIFASNTS 137 Query: 111 RYYVNLLINC-------AGLTQESLSVRTT 133 + L N AGL + Sbjct: 138 SLQITSLANATTRQDRFAGLHFFNPVPLMK 167 >4HEQ-A nrPDB Length = 146 Score = 29.1 bits (63), Expect = 1.9, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 43/119 (36%), Gaps = 16/119 (13%) Query: 4 LPVAIV-----TGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQ 58 +P A++ TG T G+ +AI + L +G+ ++ + A + G S Sbjct: 1 MPKALIVYGSTTGNTEGVAEAIAKTLNSEGMETTVVNVADVTAPGLAEGYDVVLLGCSTW 60 Query: 59 RQCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLL 117 I + P + D DR LK K +F C S V+++ Sbjct: 61 GDDEIELQEDFVPLYEDL----------DRAGLKDKKVGVFG-CGDSSYTYFCGAVDVI 108 >6C55-A nrPDB Length = 340 Score = 29.1 bits (63), Expect = 2.0, Method: Composition-based stats. Identities = 11/59 (18%), Positives = 21/59 (35%), Gaps = 2/59 (3%) Query: 5 PVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 +A+V ++ G A Q L G +I S ++ D + +Q + Sbjct: 19 KIAVVGYGSQ--GHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAEAVKQADV 75 >1ZCJ-A nrPDB Length = 463 Score = 29.1 bits (63), Expect = 2.3, Method: Composition-based stats. Identities = 25/190 (13%), Positives = 62/190 (32%), Gaps = 18/190 (9%) Query: 17 GKAICQKLFQKGLSCIILGSTKESIERT------AIDRGQLQSGLSYQRQCAIAIDFKKW 70 G+ I + G+S + + S + ++ +++ ++ + Q + F Sbjct: 49 GRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSS 108 Query: 71 PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSV 130 L F+D K+ ++ L C + N + L + ++ Sbjct: 109 TKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCT--------NTSALNVDDIAS 160 Query: 131 RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS--G 188 T Q+ ++ +F SP + + + + S I I ++ + G Sbjct: 161 STDRPQL--VIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYG 218 Query: 189 KMKVPGTSVY 198 + + Y Sbjct: 219 FVGNRMLAPY 228 >4QUK-A nrPDB Length = 319 Score = 29.1 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 40/116 (34%), Gaps = 7/116 (6%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 V VTGA+ I + + L +G + ++ D G + Q A Sbjct: 2 VVCVTGASGYIASWLVRLLLHRGYTVKATVRDPNDPKKV--DHLVKLDGAKERLQLFKAN 59 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 ++ + G+ + Y + DP + + + +N+L +CA Sbjct: 60 LLEEGAFDSVVQGCHGVFHTAS-----PFYHDVKDPQAELIDPALKGTLNVLNSCA 110 >3N58-A nrPDB Length = 464 Score = 29.1 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 22/65 (33%), Gaps = 1/65 (1%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA+V G +GK Q L G + + A+D ++ + Sbjct: 244 MMAGKVAVVCGYGD-VGKGSAQSLAGAGARVKVTEVDPICALQAAMDGFEVVTLDDAAST 302 Query: 61 CAIAI 65 I + Sbjct: 303 ADIVV 307 >3OND-A nrPDB Length = 488 Score = 29.1 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 14/34 (41%), Gaps = 1/34 (2%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIIL 34 M VA+V G +GK L Q G I+ Sbjct: 262 MIAGKVAVVAGYGD-VGKGCAAALKQAGARVIVT 294 >2E7J-A nrPDB Length = 371 Score = 29.1 bits (63), Expect = 2.5, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 37/116 (31%), Gaps = 1/116 (0%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAI 65 VA VT R A+ L +K ++ + S A G + + AI Sbjct: 71 VARVTNGAREAKFAVMHSLAKKDAWVVMDENCHYSSYVAAERAGLNIALVPKTDYPDYAI 130 Query: 66 DFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 + + ++ G Y L D K + Y V LL+N A Sbjct: 131 TPENFAQTIEETKKRGEVVLALITYPDGNYGNLPD-VKKIAKVCSEYDVPLLVNGA 185 >4WOK-A nrPDB Length = 336 Score = 28.7 bits (62), Expect = 2.6, Method: Composition-based stats. Identities = 8/83 (9%), Positives = 27/83 (32%) Query: 8 IVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDF 67 +V G IG + L +G + ++ + + ++ + Q + ++ Sbjct: 15 LVVGGAGFIGSHTAKLLAGQGYAPVVYDNLSTGHQSAVRWGDFVEGDILDQARLVETMEK 74 Query: 68 KKWPHWLDYESYDGIEYFKDRPP 90 + + + + + P Sbjct: 75 YAPVAVIHFAASAYVGESVEDPA 97 >5C1C-A nrPDB Length = 299 Score = 28.7 bits (62), Expect = 2.7, Method: Composition-based stats. Identities = 23/176 (13%), Positives = 53/176 (30%), Gaps = 6/176 (3%) Query: 30 SCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDYESYDGIEYFKDRP 89 + + G + +I Q+ + ++ + D + Sbjct: 95 NVVSDGFSMYNINVENGYGEGAQAVALVGNADQLGFYGCQFSGYQDTLYVKAGTQYYSNC 154 Query: 90 PLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTASQIQDIMNVNFMSPV 149 ++ +F + W +++ N AG S ++ S I N N + Sbjct: 155 MIEGAVDYIFGDASVW-----FGECDIVSNGAGAITASSRETSSDSGWYAIDNCNIKAAS 209 Query: 150 TMTNICIKYMMKSQRRWPELSGQSARPT-IVNISSILHSGKMKVPGTSVYSASKAA 204 ++ Y+ + R + Q++ + I+N P Y+ S A Sbjct: 210 GVSLTEEVYLGRPWRVLARVIYQNSVLSDIINPKGWTTMADGATPLYYEYNNSGAG 265 >3DC2-A nrPDB Length = 529 Score = 28.7 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 11/103 (10%), Positives = 25/103 (24%) Query: 12 ATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWP 71 IG+ + Q++ G + + L R I++ K P Sbjct: 149 GLGRIGQLVAQRIAAFGAYVVAYDPYVSPARAAQLGIELLSLDDLLARADFISVHLPKTP 208 Query: 72 HWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYV 114 + + K + ++ +V Sbjct: 209 ETAGLIDKEALAKTKPGVIIVNAARGGLVDEAALADAITGGHV 251 >4D3S-A nrPDB Length = 293 Score = 28.7 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 27/82 (32%), Gaps = 2/82 (2%) Query: 2 HYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC 61 PV ++ +G+A+ L + G + TK E A + + + Sbjct: 7 KKSPVTLI--GLGPMGQAMAGALLEAGYELTVWNRTKAKAEALAERGAAVADSPAEALRA 64 Query: 62 AIAIDFKKWPHWLDYESYDGIE 83 + H + Y +G E Sbjct: 65 GGPVLLSLTEHAVMYRVLEGAE 86 >6DEB-A nrPDB Length = 285 Score = 28.7 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 14/118 (11%), Positives = 34/118 (28%), Gaps = 3/118 (2%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIE---RTAIDRGQLQSGLSYQRQCAI 63 A++ GA+ +G+ + L G + + + + R A ++ R + Sbjct: 163 AVIIGASNIVGRPMATMLLNAGATVSVCHIKTKDLSLYTRQADLIIVAAGCVNLLRSDMV 222 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCA 121 ++ I D + +K S + + + A Sbjct: 223 KEGVIVVDVGINRLESGKIVGDVDFEEVSKKSSYITPVPGGVGPMTIAMLLENTVKSA 280 >1DB3-A nrPDB Length = 372 Score = 28.7 bits (62), Expect = 3.0, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 14/28 (50%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSC 31 VA++TG T G + + L +KG Sbjct: 1 SKVALITGVTGQDGSYLAEFLLEKGYEV 28 >3ZWA-A nrPDB Length = 742 Score = 28.7 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 25/190 (13%), Positives = 62/190 (32%), Gaps = 18/190 (9%) Query: 17 GKAICQKLFQKGLSCIILGSTKESIERT------AIDRGQLQSGLSYQRQCAIAIDFKKW 70 G+ I + G+S + + S + ++ +++ ++ + Q + F Sbjct: 328 GRGIAISFARVGISVVAVESDPKQLDAAKKIITFTLEKEASRAHQNGQASAKPKLRFSSS 387 Query: 71 PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSV 130 L F+D K+ ++ L C + N + L + ++ Sbjct: 388 TKELSTVDLVVEAVFEDMNLKKKVFAELSALCKPGAFLCT--------NTSALNVDDIAS 439 Query: 131 RTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIVNISSILHS--G 188 T Q+ ++ +F SP + + + + S I I ++ + G Sbjct: 440 STDRPQL--VIGTHFFSPAHVMRLLEVIPSRYSSPTTIATVMSLSKKIGKIGVVVGNCYG 497 Query: 189 KMKVPGTSVY 198 + + Y Sbjct: 498 FVGNRMLAPY 507 >1F14-A nrPDB Length = 310 Score = 28.7 bits (62), Expect = 3.2, Method: Composition-based stats. Identities = 28/197 (14%), Positives = 62/197 (31%), Gaps = 31/197 (15%) Query: 9 VTGATRGI-GKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQC------ 61 VT G+ G I Q G + +++ T++ + ++ + ++ ++ Sbjct: 18 VTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPKAG 77 Query: 62 -----------AIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNER 110 A + D H D +E K + L ++ +++N Sbjct: 78 DECVEKTLSTIATSTDAASVVHSTDLVVEAIVENLKVKNELFKRLDKFAAEHTIFASNTS 137 Query: 111 RYYVNLLINC-------AGLTQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQ 163 + + N AGL + + ++ S T + K+ Sbjct: 138 SLQITSIANATTRQDRFAGLHFFNPVPVMKLVE---VIKTPMTS--QKTFESLVDFSKAL 192 Query: 164 RRWPELSGQSARPTIVN 180 + P +S + IVN Sbjct: 193 GKHP-VSCKDTPGFIVN 208 >6GBN-A nrPDB Length = 438 Score = 28.3 bits (61), Expect = 3.4, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 24/65 (36%), Gaps = 1/65 (1%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M VA+V G +GK L G I+ + A+D +++ ++ Sbjct: 216 MMAGKVAVVAGYGD-VGKGSAASLRGAGARVIVTEIDPICALQAAMDGYEVKKMADAVKR 274 Query: 61 CAIAI 65 I + Sbjct: 275 ADIVV 279 >2J5V-A nrPDB Length = 367 Score = 28.3 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 34/84 (40%), Gaps = 7/84 (8%) Query: 8 IVTGATRGIGKA-ICQ------KLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 ++TG +R + +A I + +L G +I+ S + R + +L + ++ ++ Sbjct: 15 VLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQL 74 Query: 61 CAIAIDFKKWPHWLDYESYDGIEY 84 A + W S GI Sbjct: 75 LAAVGQSRLIQLWEQLFSIYGIHV 98 >2P4H-X nrPDB Length = 322 Score = 28.3 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 32/111 (28%), Gaps = 3/111 (2%) Query: 9 VTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFK 68 VTG T +G I + L + G S +R L + ++ D Sbjct: 6 VTGGTGFLGSWIIKSLLENGYSVNTTIRADPERKRDVSFLTNLPG--ASEKLHFFNADLS 63 Query: 69 KWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN 119 P + F P+ S + K + + + +N Sbjct: 64 N-PDSFAAAIEGCVGIFHTASPIDFAVSEPEEIVTKRTVDGALGILKACVN 113 >2GO1-A nrPDB Length = 401 Score = 28.3 bits (61), Expect = 4.1, Method: Composition-based stats. Identities = 28/219 (12%), Positives = 58/219 (26%), Gaps = 20/219 (9%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 MH VA IG A+ ++L + + + + + L + + Sbjct: 193 MHVGTVA-----AGRIGLAVLRRLAP--FDVHLHYTDRHRLPESVEKELNLTWHATREDM 245 Query: 61 CA----IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNL 116 + ++ P + + ++ FK + + + + Sbjct: 246 YPVCDVVTLNCPLHPETEHMINDETLKLFKRGAYIVNTARGKLCDRDAVARALESGRL-- 303 Query: 117 LINCAGLTQESLSVRTTASQI-QDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSAR 175 AG + + M N M+P + L Sbjct: 304 ----AGYAGDVWFPQPAPKDHPWRTMPYNGMTPHISGTTLTAQARYAAGTREILECFFEG 359 Query: 176 PTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAA 214 I + I+ G + G Y SK + +E A Sbjct: 360 RPIRDEYLIVQGGALAGTGAHSY--SKGNATGGSEEAAK 396 >3X2F-A nrPDB Length = 411 Score = 28.3 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 13/78 (16%), Positives = 21/78 (26%), Gaps = 3/78 (3%) Query: 17 GKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLDY 76 G+ I + G I+ +D + + + IA D Sbjct: 209 GRGIALRAAGLGARVIVTEVDPVKAVEAIMDGFTV---MPMKEAVKIADFVITASGNTDV 265 Query: 77 ESYDGIEYFKDRPPLKQK 94 S + I KD L Sbjct: 266 LSKEDILSLKDGAVLANA 283 >5XW3-A nrPDB Length = 315 Score = 27.9 bits (60), Expect = 4.3, Method: Composition-based stats. Identities = 22/132 (16%), Positives = 40/132 (30%), Gaps = 9/132 (6%) Query: 10 TGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGL-SYQRQCAIAIDFK 68 T GIG A+ Q L I+ K SIE+ + + + + + Q K Sbjct: 71 TAGNTGIGLALAA--LQHDLRVIVCVPEKFSIEKQELMKALGATVVHTPTEQGMTGAIAK 128 Query: 69 KWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL--TQE 126 + + F + + + TL + +N+ + AG T Sbjct: 129 AKELVNEIPNSYSPSQFANEANPRAYFKTL----GPELWSALNGEINIFVAGAGTGGTFM 184 Query: 127 SLSVRTTASQIQ 138 + I Sbjct: 185 GTASYLKEKNID 196 >1LU9-A nrPDB Length = 287 Score = 27.9 bits (60), Expect = 4.3, Method: Composition-based stats. Identities = 8/44 (18%), Positives = 16/44 (36%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQ 50 A+V T +G L +G ++ G + + A + Sbjct: 122 AVVLAGTGPVGMRSAALLAGEGAEVVLCGRKLDKAQAAADSVNK 165 >3K6J-A nrPDB Length = 460 Score = 27.9 bits (60), Expect = 4.4, Method: Composition-based stats. Identities = 20/105 (19%), Positives = 40/105 (38%), Gaps = 7/105 (6%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIE---RTAIDRGQLQSGLSYQRQ 60 VAI+ G T +GKA+ G+ ++ ++ + R + L+ +R Sbjct: 55 NSVAIIGGGT--MGKAMAICFGLAGIETFLVVRNEQRCKQELEVMYAREKSFKRLNDKRI 112 Query: 61 CAIAIDFKKWPHWLDYESYDGI--EYFKDRPPLKQKYSTLFDPCN 103 I + K + + D I +D K+ ++ L + C Sbjct: 113 EKINANLKITSDFHKLSNCDLIVESVIEDMKLKKELFANLENICK 157 >4I1I-A nrPDB Length = 345 Score = 27.9 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 28/90 (31%), Gaps = 2/90 (2%) Query: 1 MHYLPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 M + VA VTGA IG A+ L +G + + L + Sbjct: 22 MSAVKVA-VTGAAGQIGYALV-PLIARGALLGPTTPVELRLLDIEPALKALAGVEAELED 79 Query: 61 CAIAIDFKKWPHWLDYESYDGIEYFKDRPP 90 CA + K ++DG+ Sbjct: 80 CAFPLLDKVVVTADPRVAFDGVAIAIMCGA 109 >2W21-A nrPDB Length = 259 Score = 27.9 bits (60), Expect = 5.0, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 33/84 (39%), Gaps = 7/84 (8%) Query: 8 IVTGATRGIGKAI-------CQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQ 60 ++TG +R + +A C +L G +I+ S + R + +L + ++ ++ Sbjct: 15 VLTGGSRRLNRAHIVELVRQCAQLHAAGHRIVIVTSGAIAAGREHLGYPELPATIASKQL 74 Query: 61 CAIAIDFKKWPHWLDYESYDGIEY 84 A + W S GI Sbjct: 75 LAAVGQSRLIQLWEQLFSIYGIHV 98 >4Y4N-A nrPDB Length = 286 Score = 27.5 bits (59), Expect = 5.7, Method: Composition-based stats. Identities = 15/132 (11%), Positives = 36/132 (27%), Gaps = 8/132 (6%) Query: 6 VAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQ------LQSGLSYQR 59 VAIV G G+ + + ++G ++L T + R Sbjct: 55 VAIVGGGPSGL--TAARYIAKEGYKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADEILR 112 Query: 60 QCAIAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLIN 119 + + ++ + L + + L + ++IN Sbjct: 113 EVGVKLEKVEGEDGLYTADSVEVPAKLAVGAIDAGAKVLTGIVVEDLVLRENRVAGVVIN 172 Query: 120 CAGLTQESLSVR 131 + + L + Sbjct: 173 SYAIEKAGLHID 184 >3TX2-A nrPDB Length = 251 Score = 27.5 bits (59), Expect = 6.0, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 17/36 (47%) Query: 7 AIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIE 42 A+VT A + AI L ++G + I+L I Sbjct: 18 ALVTAAGDRLASAITGALAERGKAMIVLTGGGTGIA 53 >4E0B-A nrPDB Length = 313 Score = 27.5 bits (59), Expect = 6.1, Method: Composition-based stats. Identities = 16/120 (13%), Positives = 35/120 (29%), Gaps = 6/120 (5%) Query: 4 LPVAIVTGATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAI 63 + VA++ GA GIG+A+ L + + + ++ A + + LS+ Sbjct: 4 MKVAVI-GAAGGIGQALALLLKNR-----LPAGSDLALYDIAPVTPGVAADLSHIPTHVS 57 Query: 64 AIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGL 123 + E D + N + ++ A + Sbjct: 58 IKGYAGEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACI 117 >3ORR-A nrPDB Length = 377 Score = 27.5 bits (59), Expect = 6.4, Method: Composition-based stats. Identities = 15/129 (11%), Positives = 39/129 (30%), Gaps = 9/129 (6%) Query: 16 IGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKWPHWLD 75 +GK + Q + G ++L +++ R + + + + Sbjct: 23 LGKMMAQSAQKMGYKVVVLDPSEDCPCRYVAHEFIQAKYDDEKALNQLGQKCDVITYEFE 82 Query: 76 YESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAGLTQESLSVRTTAS 135 S ++ ++ + Q Y + ++ + E AG T+ + S Sbjct: 83 NISAQQLKLLCEKYNIPQGYQAIQLLQDRLTEKETLKS-------AG-TKVVPFISVKES 134 Query: 136 -QIQDIMNV 143 I + Sbjct: 135 TDIDKAIET 143 >5GMK-P nrPDB Length = 379 Score = 27.5 bits (59), Expect = 6.5, Method: Composition-based stats. Identities = 7/39 (17%), Positives = 19/39 (48%) Query: 224 FTISPGLVKGTDMIQNLPVEAKEMLERTIGASGTSAPAE 262 TI+ G +K ++ ++N +A++ + + + E Sbjct: 195 NTINDGFMKLSEALENADKKARQEIRSKMELKRLAMEQE 233 >2OHJ-A nrPDB Length = 404 Score = 27.5 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 7/106 (6%), Positives = 22/106 (20%) Query: 11 GATRGIGKAICQKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCAIAIDFKKW 70 G+TR + AI + +G+ + ++ D + + Sbjct: 268 GSTRKMAHAIAEGAMSEGVDVRVYCLHEDDRSEIVKDILESGAIALGAPTIYDEPYPSVG 327 Query: 71 PHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNL 116 + + + ++ Sbjct: 328 DLLMYLRGLKFNRTLTRKALVFGSMGGNGGATGTMKELLAEAGFDV 373 >4OAN-A nrPDB Length = 333 Score = 27.1 bits (58), Expect = 7.6, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 21/39 (53%) Query: 237 IQNLPVEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTA 275 + LP + ++++ R I A+G + A++A+ L A Sbjct: 248 WERLPADLRDIVARNINAAGVNQRADVAKLNAGLKDELA 286 >3KAQ-A nrPDB Length = 147 Score = 27.1 bits (58), Expect = 7.8, Method: Composition-based stats. Identities = 16/79 (20%), Positives = 31/79 (39%), Gaps = 4/79 (5%) Query: 4 LPVAIVTGATRGIGKAICQKL----FQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQR 59 V I+ G++ G ++I QKL G +L + + S + A + G S Sbjct: 1 SKVLILFGSSTGNTESIAQKLEELVAAGGHEVTLLNAAEASADNLADGYDAVLMGCSAWG 60 Query: 60 QCAIAIDFKKWPHWLDYES 78 + + P + + E+ Sbjct: 61 MEDLELQDDFAPLFDEMEN 79 >1YXY-A nrPDB Length = 234 Score = 27.1 bits (58), Expect = 8.5, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 14/36 (38%), Gaps = 1/36 (2%) Query: 191 KVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTI 226 +PG +YS + + A E IR ++ Sbjct: 24 ALPGEPLYSET-GGIMPLMAKAAQEAGAVGIRANSV 58 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.117 0.320 Lambda K H 0.267 0.0359 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,515,956 Number of Sequences: 36641 Number of extensions: 351961 Number of successful extensions: 2319 Number of sequences better than 10.0: 263 Number of HSP's better than 10.0 without gapping: 334 Number of HSP's successfully gapped in prelim test: 77 Number of HSP's that attempted gapping in prelim test: 1273 Number of HSP's gapped (non-prelim): 601 length of query: 278 length of database: 10,336,785 effective HSP length: 96 effective length of query: 182 effective length of database: 6,819,249 effective search space: 1241103318 effective search space used: 1241103318 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 58 (27.1 bits)