BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P35523 (988 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6QVC-B nrPDB 2032 0.0 5TR1-A nrPDB 457 e-128 3ORG-A nrPDB 223 3e-58 1KPL-A nrPDB 64 3e-10 3EJY-A nrPDB 39 0.008 3ND0-A nrPDB 39 0.009 1QOR-A nrPDB 31 2.2 5NA1-A nrPDB 30 6.8 1TC5-A nrPDB 29 8.9 >6QVC-B nrPDB Length = 988 Score = 2032 bits (5264), Expect = 0.0, Method: Compositional matrix adjust. Identities = 988/988 (100%), Positives = 988/988 (100%) Query: 1 MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQ 60 MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQ Sbjct: 1 MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQ 60 Query: 61 IYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIF 120 IYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIF Sbjct: 61 IYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIF 120 Query: 121 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH 180 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH Sbjct: 121 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH 180 Query: 181 LISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS 240 LISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS Sbjct: 181 LISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS 240 Query: 241 ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR 300 ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR Sbjct: 241 ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR 300 Query: 301 NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGL 360 NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGL Sbjct: 301 NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGL 360 Query: 361 LGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMP 420 LGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMP Sbjct: 361 LGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMP 420 Query: 421 REAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP 480 REAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP Sbjct: 421 REAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP 480 Query: 481 CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTV 540 CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTV Sbjct: 481 CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTV 540 Query: 541 STAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSK 600 STAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSK Sbjct: 541 STAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSK 600 Query: 601 YTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQAL 660 YTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQAL Sbjct: 601 YTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQAL 660 Query: 661 LQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS 720 LQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS Sbjct: 661 LQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS 720 Query: 721 GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRAR 780 GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRAR Sbjct: 721 GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRAR 780 Query: 781 PTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTL 840 PTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTL Sbjct: 781 PTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTL 840 Query: 841 FSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAP 900 FSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAP Sbjct: 841 FSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAP 900 Query: 901 PSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP 960 PSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP Sbjct: 901 PSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP 960 Query: 961 GLEEELADILQGPSLRSTDEEDEDELIL 988 GLEEELADILQGPSLRSTDEEDEDELIL Sbjct: 961 GLEEELADILQGPSLRSTDEEDEDELIL 988 >5TR1-A nrPDB Length = 671 Score = 457 bits (1176), Expect = e-128, Method: Compositional matrix adjust. Identities = 250/568 (44%), Positives = 370/568 (65%), Gaps = 17/568 (2%) Query: 110 VRRKL---GEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVT 166 ++RKL GED FL +LG+LMAL+S++M + + ++A+KW Y ++ S L++L W Sbjct: 14 LKRKLFCVGEDWYFLTVLGVLMALISFTMSFTVGRVVRAHKWLYREIGDSHLLRYLSWTV 73 Query: 167 FPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSG 226 +P+ L+ FS+ F I+P + GSGIPE+KTIL GVVL++YL +K F AK V LT L SG Sbjct: 74 YPVALVSFSSGFSQSITPFSGGSGIPELKTILSGVVLEDYLDIKNFGAKAVGLTCTLASG 133 Query: 227 --IPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLG 284 I +GK GPFVH++ + AA L + + G E +++L G AVGV F P Sbjct: 134 STIFLGKVGPFVHLSVMIAAYLGRVRAKATGESENKSKRNEMLVAGAAVGVATVFAAPFS 193 Query: 285 GVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFD 344 GVLF IEV S++F+V +YWRGFFAAT AF+FR+LAV+N + TIT+L++T+FR++ PFD Sbjct: 194 GVLFCIEVVSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVEVPFD 253 Query: 345 LKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASF 404 L E+ F A+G CG+ +++ R+ + V+ + LS+ +A + LY + V+AS Sbjct: 254 LPEIFFFVALGAICGVASCAYLFCQRKFLGFVKTNPVLSKLMATSKPLYSALAALVLASV 313 Query: 405 TFPPGMGQFMAGELMPREAISTLFDNNTW---VKHAG-------DPESLGQSAVWIHPRV 454 T+PPG G+FMA L RE + +L D+N+W + A DP++L W HP+ Sbjct: 314 TYPPGAGRFMASRLSMREYLDSLLDHNSWALLTRQASPPWPVEPDPQNLWFE--WYHPQF 371 Query: 455 NVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDD 514 + + F VMKFWM I+ATT+P+P G FMP+F+ GAA GRL+GE +++ FP+GI+ Sbjct: 372 TIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFIFGAAIGRLLGEALSVAFPEGIVAGG 431 Query: 515 IIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 574 + I+PGGYA+ GAAA +GAV+H++STA++ FELTGQI H LP+++AV+ AN +AQS Q Sbjct: 432 VTNPIMPGGYALAGAAAFSGAVTHSISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQ 491 Query: 575 PSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTV 634 PS YD I VKKLPYLP + ++S + + VE M R + ++ E+ ++ +T + Sbjct: 492 PSFYDGTIIVKKLPYLPWIRGRKISSHRVTVEHFMNRAITTLAKDTPQEEVVKVVTSTDM 551 Query: 635 KTLPLVDSKDSMILLGSVERSELQALLQ 662 PLV S +S L+G++ R++L LQ Sbjct: 552 AEYPLVASTESQTLVGTMRRAQLVQALQ 579 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 39/69 (56%) Query: 807 QEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEEL 866 Q++ Q + + C ++ +L +T+LH+ H LF LL L +VTS G+ G ++ EL Sbjct: 589 QQRCLQDILAEGCPVEPVTLKLSPETSLHQAHNLFELLNLQSLFVTSQGRAVGFVSWVEL 648 Query: 867 QKAIEGHTK 875 +KAI T Sbjct: 649 EKAISKLTN 657 >3ORG-A nrPDB Length = 632 Score = 223 bits (569), Expect = 3e-58, Method: Compositional matrix adjust. Identities = 150/476 (31%), Positives = 250/476 (52%), Gaps = 45/476 (9%) Query: 120 FLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFC 179 FL LLG+ AL +++D ++ L+ + +++ ++++V + L L S +C Sbjct: 13 FLTLLGVTAALFIFAVD-LAVHGLEELRMKISRLAGRFA-GYILYVVSGVALCLLSTFWC 70 Query: 180 HLISPQAVGSGIPEMKTILRGVV--LKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVH 237 ++S +A GSG+P+MK+IL G ++ L ++ AK + L +G G+PVG EGP VH Sbjct: 71 AVLSTEAEGSGLPQMKSILSGFYDKMRSALELRVLFAKALGLICAIGGGLPVGWEGPNVH 130 Query: 238 IASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYF 297 IA I A + + VF + L CAVG+ FG PLGGVL+SIE ++++ Sbjct: 131 IACIIAHQFYR-LGVFKELCTDRALRLQTLAAACAVGLASSFGAPLGGVLYSIETIASFY 189 Query: 298 AVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGIC 357 V+ +W+G +A A V+ +L + A TNF + L +A +G Sbjct: 190 LVQAFWKGVLSALSGAIVYELL----YTTPLVEAFEGTNFDASDVSRTQTL-LYAILGAL 244 Query: 358 CGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGE 417 G+LGA+F+ R + +H + +R G+V ++ +P F Sbjct: 245 MGVLGALFIRCVRSIYELRMRH-----YPGTNRYFLVGVVALFASALQYP-----FRLFA 294 Query: 418 LMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTM 477 L PR I+ LF + + G + + + P ++KF + ++ + Sbjct: 295 LDPRATINDLFKAVPLYQ----TDHFGWTELILMP------------IIKFILVALSIGL 338 Query: 478 PIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVS 537 P+P G F+P F++GA FGRL GE+M ++F + I+PG YAV+GAAA T V+ Sbjct: 339 PLPAGVFVPSFLIGAGFGRLYGELMRVVFGNA---------IVPGSYAVVGAAAFTAGVT 389 Query: 538 HTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDL 593 +S AVI FE+TGQI H++P++++V+LA +V + SLY++++ +K LPY+P L Sbjct: 390 RALSCAVIIFEVTGQIRHLVPVLISVLLAVIVGNAFNRSLYETLVLMKHLPYMPIL 445 Score = 30.8 bits (68), Expect = 3.0, Method: Compositional matrix adjust. Identities = 44/176 (25%), Positives = 63/176 (35%), Gaps = 32/176 (18%) Query: 703 GRPESFAFVDEDEDEDLSGKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAG 762 G P F + E + + G E P+ + P A NG L G A Sbjct: 464 GEPHLF---PDSEPQHIKGILEKFPNRLVFPVIDA-------NGYLLG----------AI 503 Query: 763 QRPSIFQSLLHCLLGRARPTKKKTTQ---DSTDLVDNMSPEEIEAWEQEQLS-------- 811 R I L H L P T D+ DL +N+ E E S Sbjct: 504 SRKEIVDRLQHVLEDVPEPIAGHRTLVLLDAADLSENIEGLVDETPSGEHSSKGKRTATV 563 Query: 812 -QPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEEL 866 +P D SP + + + + H LF +L + YVT GKL G++ E++ Sbjct: 564 LEPTSSLVVPCDVSPIVVTSYSLVRQLHFLFVMLMPSMIYVTERGKLVGIVEREDV 619 >1KPL-A nrPDB Length = 473 Score = 63.9 bits (154), Expect = 3e-10, Method: Compositional matrix adjust. Identities = 110/440 (25%), Positives = 176/440 (40%), Gaps = 84/440 (19%) Query: 161 FLVWVTFPLVLILFSALFCHL-------ISPQAVGSGIPEMKTILRGVVLKEYLTMKAFV 213 FL+W PL IL SAL + +P+A GSGIPE++ L L+ + Sbjct: 76 FLLW---PLAFIL-SALLAMVGYFLVRKFAPEAGGSGIPEIEGALE--ELRPVRWWRVLP 129 Query: 214 AKVVALTAGLGSGIPVGKEGPFVHIA-SICAAVLSKFMSVFCGVYEQPYYYSDILTVGCA 272 K + LG+G+ +G+EGP V I ++ VL F +L G A Sbjct: 130 VKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFR------MRSAEARHTLLATGAA 183 Query: 273 VGVGCCFGTPLGGVLFSIEVTSTYF-----AVRNYWRGFFAATFSAFVFRVLAVWNKDAV 327 G+ F PL G+LF IE F +++ + G S+ VFR ++N +A Sbjct: 184 AGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTG---VIMSSIVFR---IFNGEAP 237 Query: 328 TITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLA 387 I D P + L + +GI G++G VF L V + + + Q Sbjct: 238 II----EVGKLSDAPVN--TLWLYLILGIIFGVVGPVFNSL-------VLRTQDMFQ--- 281 Query: 388 KHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLGQ-- 445 +F GE+ + + +P + G Sbjct: 282 ------------------------RFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGF 317 Query: 446 SAVWIHPRVNVVIIIFLF-FVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAM 504 + + I N + + LF F+ + +++ + P G F P+ LG G G A+ Sbjct: 318 NLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAV 377 Query: 505 LFPDGILFDDIIYKILPGGYAVIGAAALTGA-VSHTVSTAVICFELTGQIAHILPMMVAV 563 LFP Y + G +A+ G AL A V ++ V+ E+T ILPM++ Sbjct: 378 LFPQ--------YHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITC 429 Query: 564 ILANMVAQSLQPS-LYDSII 582 + A ++AQ L LY +I+ Sbjct: 430 LGATLLAQFLGGKPLYSTIL 449 >3EJY-A nrPDB Length = 473 Score = 39.3 bits (90), Expect = 0.008, Method: Compositional matrix adjust. Identities = 29/114 (25%), Positives = 52/114 (45%), Gaps = 9/114 (7%) Query: 459 IIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYK 518 ++ FV + +++ + P G F P+ LG G G + LFP Y Sbjct: 332 MLVFIFVARVITTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQ--------YH 383 Query: 519 ILPGGYAVIGAAALTGA-VSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQ 571 + G +A+ G AL A + ++ ++ E+T ILPM++ + A ++AQ Sbjct: 384 LEAGTFAIAGMGALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQ 437 >3ND0-A nrPDB Length = 466 Score = 39.3 bits (90), Expect = 0.009, Method: Compositional matrix adjust. Identities = 89/433 (20%), Positives = 158/433 (36%), Gaps = 65/433 (15%) Query: 147 KWSYAQMQPSLPLQFLVWVTFPLV---LILFSALFCHLISPQAVGSGIPEMKTILRGVVL 203 +W Q P+ L W+ L+ ++ S +P GSGIP+++ L G + Sbjct: 58 QWRSQLAQILAPIPPLAWLVTALISGGMVALSFWLMKRFAPDTSGSGIPQIEGHLEGKL- 116 Query: 204 KEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYY 263 + + K+V LG+G+ G EGP + + + + F E Sbjct: 117 -PLVWQRVLPIKLVGGFLSLGAGMLAGFEGPTIQMGGSIGQMTGGW---FKATQENQRI- 171 Query: 264 SDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVRN--YWRGFFAATFSAFVFRVLAV 321 ++ VG G+ F PL GV E F + Y F + + R++ Sbjct: 172 --LIAVGAGAGLATAFNAPLAGVALIGEEMHPRFRSQTLAYHSLLFGCVMATIILRMI-- 227 Query: 322 WNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKA 381 + I +L T F+ P D L F +GI G++G F +R + + Sbjct: 228 --RGQSAIISL--TEFK-RVPLD--SLWMFIILGILFGVMGYTF---NRGLFKVLDWFDR 277 Query: 382 LSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPE 441 L K + G + +++ F P + GD Sbjct: 278 LPPLATKWKGFLLGSIIGILSLFPLP--------------------------LTDGGD-- 309 Query: 442 SLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEI 501 + +W + + L F +F ++++ G F P+ + + + Sbjct: 310 ---NAVLWAFNSQSHFSTLILVFCGRFLLTLICYGSGAIGGIFAPMLGIASIVSVAMARH 366 Query: 502 MAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTVSTAV-ICFELTGQIAHILPMM 560 +LFP I P A+ G AL A TA+ + E+T ILP++ Sbjct: 367 FHLLFPSQI--------PEPAVMAIAGMGALVAATVRAPLTAILLTIEMTDNYFVILPLL 418 Query: 561 VAVILANMVAQSL 573 V ++A++VA++L Sbjct: 419 VTCLVASVVAEAL 431 >1QOR-A nrPDB Length = 327 Score = 31.2 bits (69), Expect = 2.2, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 5/87 (5%) Query: 60 QIYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGI 119 Q+ + +E +R ++I KK DS D + + DC+ R G +V + Sbjct: 188 QVINYREEDLVERLKEITGGKKV--RVVYDSVGRDTWERSLDCLQRRGLMVSFGNSSGAV 245 Query: 120 FLVLLGLLMALVSWSMDYVSAKSLQAY 146 V LG+L S YV+ SLQ Y Sbjct: 246 TGVNLGILNQKGSL---YVTRPSLQGY 269 >5NA1-A nrPDB Length = 408 Score = 29.6 bits (65), Expect = 6.8, Method: Compositional matrix adjust. Identities = 25/97 (25%), Positives = 42/97 (43%), Gaps = 10/97 (10%) Query: 197 ILRG-VVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASIC----AAVLSKFMS 251 + RG +V K+ LT+ + + + + IP G+E P A I +V Sbjct: 284 VKRGRIVTKQDLTINGY--DNIFVIGDCSAFIPAGEERPLPTTAQIAMQQGESVAKNIKR 341 Query: 252 VFCGVYEQPYYYSD---ILTVGCAVGVGCCFGTPLGG 285 + G + + Y D + ++G GVG FG P+ G Sbjct: 342 ILNGESTEEFEYVDRGTVCSLGSHDGVGMVFGKPIAG 378 >1TC5-A nrPDB Length = 194 Score = 29.3 bits (64), Expect = 8.9, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 8/69 (11%) Query: 178 FCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKA-----FVAKVVALTAGLGSGIPVGKE 232 FCH + V G+ E + G E KA + ++V++ T G G+ E Sbjct: 129 FCHFVR---VARGVDESRVDANGAPRSEGDAPKAEGWIKYNSRVISGTFGNRQGLRFESE 185 Query: 233 GPFVHIASI 241 GPF H+ I Sbjct: 186 GPFTHMFDI 194 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6QVC-B nrPDB 1739 0.0 5TR1-A nrPDB 759 0.0 3ORG-A nrPDB 551 e-157 1KPL-A nrPDB 380 e-105 Sequences not found previously or not previously below threshold: 3EJY-A nrPDB 275 6e-74 3ND0-A nrPDB 183 3e-46 6D0J-A nrPDB 50 3e-06 5M95-A nrPDB 37 0.043 3V94-A nrPDB 35 0.14 6GB2-BJ nrPDB 33 0.60 2YVZ-A nrPDB 32 1.4 2YVX-A nrPDB 32 1.5 3J9M-I nrPDB 31 2.5 3ZUY-A nrPDB 30 5.3 2AVN-A nrPDB 30 6.0 4BWZ-A nrPDB 29 7.9 4HE8-N nrPDB 29 9.6 3CLL-A nrPDB 29 9.9 >6QVC-B nrPDB Length = 988 Score = 1739 bits (4504), Expect = 0.0, Method: Composition-based stats. Identities = 988/988 (100%), Positives = 988/988 (100%) Query: 1 MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQ 60 MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQ Sbjct: 1 MEQSRSQQRGGEQSWWGSDPQYQYMPFEHCTSYGLPSENGGLQHRLRKDAGPRHNVHPTQ 60 Query: 61 IYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIF 120 IYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIF Sbjct: 61 IYGHHKEQFSDREQDIGMPKKTGSSSTVDSKDEDHYSKCQDCIHRLGQVVRRKLGEDGIF 120 Query: 121 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH 180 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH Sbjct: 121 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH 180 Query: 181 LISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS 240 LISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS Sbjct: 181 LISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIAS 240 Query: 241 ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR 300 ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR Sbjct: 241 ICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR 300 Query: 301 NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGL 360 NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGL Sbjct: 301 NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCGL 360 Query: 361 LGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMP 420 LGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMP Sbjct: 361 LGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELMP 420 Query: 421 REAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP 480 REAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP Sbjct: 421 REAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPIP 480 Query: 481 CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTV 540 CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTV Sbjct: 481 CGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVSHTV 540 Query: 541 STAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSK 600 STAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSK Sbjct: 541 STAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSK 600 Query: 601 YTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQAL 660 YTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQAL Sbjct: 601 YTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQAL 660 Query: 661 LQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS 720 LQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS Sbjct: 661 LQRHLCPERRLRAAQEMARKLSELPYDGKARLAGEGLPGAPPGRPESFAFVDEDEDEDLS 720 Query: 721 GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRAR 780 GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRAR Sbjct: 721 GKSELPPSLALHPSTTAPLSPEEPNGPLPGHKQQPEAPEPAGQRPSIFQSLLHCLLGRAR 780 Query: 781 PTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTL 840 PTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTL Sbjct: 781 PTKKKTTQDSTDLVDNMSPEEIEAWEQEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTL 840 Query: 841 FSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAP 900 FSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAP Sbjct: 841 FSLLGLHLAYVTSMGKLRGVLALEELQKAIEGHTKSGVQLRPPLASFRNTTSTRKSTGAP 900 Query: 901 PSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP 960 PSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP Sbjct: 901 PSSAENWNLPEDRPGATGTGDVIAASPETPVPSPSPEPPLSLAPGKVEGELEELELVESP 960 Query: 961 GLEEELADILQGPSLRSTDEEDEDELIL 988 GLEEELADILQGPSLRSTDEEDEDELIL Sbjct: 961 GLEEELADILQGPSLRSTDEEDEDELIL 988 >5TR1-A nrPDB Length = 671 Score = 759 bits (1959), Expect = 0.0, Method: Composition-based stats. Identities = 250/568 (44%), Positives = 370/568 (65%), Gaps = 17/568 (2%) Query: 110 VRRKL---GEDGIFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVT 166 ++RKL GED FL +LG+LMAL+S++M + + ++A+KW Y ++ S L++L W Sbjct: 14 LKRKLFCVGEDWYFLTVLGVLMALISFTMSFTVGRVVRAHKWLYREIGDSHLLRYLSWTV 73 Query: 167 FPLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSG 226 +P+ L+ FS+ F I+P + GSGIPE+KTIL GVVL++YL +K F AK V LT L SG Sbjct: 74 YPVALVSFSSGFSQSITPFSGGSGIPELKTILSGVVLEDYLDIKNFGAKAVGLTCTLASG 133 Query: 227 --IPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLG 284 I +GK GPFVH++ + AA L + + G E +++L G AVGV F P Sbjct: 134 STIFLGKVGPFVHLSVMIAAYLGRVRAKATGESENKSKRNEMLVAGAAVGVATVFAAPFS 193 Query: 285 GVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFD 344 GVLF IEV S++F+V +YWRGFFAAT AF+FR+LAV+N + TIT+L++T+FR++ PFD Sbjct: 194 GVLFCIEVVSSHFSVWDYWRGFFAATCGAFMFRLLAVFNSEQETITSLYKTSFRVEVPFD 253 Query: 345 LKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASF 404 L E+ F A+G CG+ +++ R+ + V+ + LS+ +A + LY + V+AS Sbjct: 254 LPEIFFFVALGAICGVASCAYLFCQRKFLGFVKTNPVLSKLMATSKPLYSALAALVLASV 313 Query: 405 TFPPGMGQFMAGELMPREAISTLFDNNTW---VKHAG-------DPESLGQSAVWIHPRV 454 T+PPG G+FMA L RE + +L D+N+W + A DP++L W HP+ Sbjct: 314 TYPPGAGRFMASRLSMREYLDSLLDHNSWALLTRQASPPWPVEPDPQNLWFE--WYHPQF 371 Query: 455 NVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDD 514 + + F VMKFWM I+ATT+P+P G FMP+F+ GAA GRL+GE +++ FP+GI+ Sbjct: 372 TIFGTLAFFLVMKFWMLILATTIPMPAGYFMPIFIFGAAIGRLLGEALSVAFPEGIVAGG 431 Query: 515 IIYKILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQ 574 + I+PGGYA+ GAAA +GAV+H++STA++ FELTGQI H LP+++AV+ AN +AQS Q Sbjct: 432 VTNPIMPGGYALAGAAAFSGAVTHSISTALLAFELTGQIVHALPVLMAVLAANAIAQSCQ 491 Query: 575 PSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVRDVKFVSASYTYGELRTLLQTTTV 634 PS YD I VKKLPYLP + ++S + + VE M R + ++ E+ ++ +T + Sbjct: 492 PSFYDGTIIVKKLPYLPWIRGRKISSHRVTVEHFMNRAITTLAKDTPQEEVVKVVTSTDM 551 Query: 635 KTLPLVDSKDSMILLGSVERSELQALLQ 662 PLV S +S L+G++ R++L LQ Sbjct: 552 AEYPLVASTESQTLVGTMRRAQLVQALQ 579 Score = 119 bits (299), Expect = 5e-27, Method: Composition-based stats. Identities = 24/69 (34%), Positives = 39/69 (56%) Query: 807 QEQLSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEEL 866 Q++ Q + + C ++ +L +T+LH+ H LF LL L +VTS G+ G ++ EL Sbjct: 589 QQRCLQDILAEGCPVEPVTLKLSPETSLHQAHNLFELLNLQSLFVTSQGRAVGFVSWVEL 648 Query: 867 QKAIEGHTK 875 +KAI T Sbjct: 649 EKAISKLTN 657 >3ORG-A nrPDB Length = 632 Score = 551 bits (1420), Expect = e-157, Method: Composition-based stats. Identities = 163/551 (29%), Positives = 280/551 (50%), Gaps = 52/551 (9%) Query: 120 FLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFC 179 FL LLG+ AL +++D ++ L+ + +++ ++++V + L L S +C Sbjct: 13 FLTLLGVTAALFIFAVD-LAVHGLEELRMKISRLAGRFA-GYILYVVSGVALCLLSTFWC 70 Query: 180 HLISPQAVGSGIPEMKTILRGVV--LKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVH 237 ++S +A GSG+P+MK+IL G ++ L ++ AK + L +G G+PVG EGP VH Sbjct: 71 AVLSTEAEGSGLPQMKSILSGFYDKMRSALELRVLFAKALGLICAIGGGLPVGWEGPNVH 130 Query: 238 IASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYF 297 IA I A + + VF + L CAVG+ FG PLGGVL+SIE ++++ Sbjct: 131 IACIIAHQFYR-LGVFKELCTDRALRLQTLAAACAVGLASSFGAPLGGVLYSIETIASFY 189 Query: 298 AVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGIC 357 V+ +W+G +A A V+ +L + A TNF + L +A +G Sbjct: 190 LVQAFWKGVLSALSGAIVYELL----YTTPLVEAFEGTNFDASDVSRTQTL-LYAILGAL 244 Query: 358 CGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGE 417 G+LGA+F+ R + +H + +R G+V ++ +P F Sbjct: 245 MGVLGALFIRCVRSIYELRMRH-----YPGTNRYFLVGVVALFASALQYP-----FRLFA 294 Query: 418 LMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTM 477 L PR I+ LF + + G + + + P ++KF + ++ + Sbjct: 295 LDPRATINDLFKAVPLYQ----TDHFGWTELILMP------------IIKFILVALSIGL 338 Query: 478 PIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGAVS 537 P+P G F+P F++GA FGRL GE+M ++F + I+PG YAV+GAAA T V+ Sbjct: 339 PLPAGVFVPSFLIGAGFGRLYGELMRVVFGNA---------IVPGSYAVVGAAAFTAGVT 389 Query: 538 HTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQ 597 +S AVI FE+TGQI H++P++++V+LA +V + SLY++++ +K LPY+P L ++ Sbjct: 390 RALSCAVIIFEVTGQIRHLVPVLISVLLAVIVGNAFNRSLYETLVLMKHLPYMPILRRDR 449 Query: 598 LSKYTIFVEDIM--VRDVKFVSASYTYGELRTLLQT-TTVKTLPLVDSKDSMILLGSVER 654 + +IM + + ++ +L+ P++D+ + LLG++ R Sbjct: 450 --SPEMTAREIMHPIEGEPHLFPDSEPQHIKGILEKFPNRLVFPVIDA--NGYLLGAISR 505 Query: 655 SELQALLQRHL 665 E+ LQ L Sbjct: 506 KEIVDRLQHVL 516 Score = 35.9 bits (81), Expect = 0.081, Method: Composition-based stats. Identities = 32/128 (25%), Positives = 50/128 (39%), Gaps = 15/128 (11%) Query: 761 AGQRPSIFQSLLHCLLGRARPTKKKTTQ---DSTDLVDNMSP--EEIEAWEQEQ------ 809 A R I L H L P T D+ DL +N+ +E + E Sbjct: 502 AISRKEIVDRLQHVLEDVPEPIAGHRTLVLLDAADLSENIEGLVDETPSGEHSSKGKRTA 561 Query: 810 -LSQPVCFDSCCIDQSPFQLVEQTTLHKTHTLFSLLGLHLAYVTSMGKLRGVLALEELQK 868 + +P D SP + + + + H LF +L + YVT GKL G++ E + Sbjct: 562 TVLEPTSSLVVPCDVSPIVVTSYSLVRQLHFLFVMLMPSMIYVTERGKLVGIV---ERED 618 Query: 869 AIEGHTKS 876 G++ S Sbjct: 619 VAYGYSNS 626 >1KPL-A nrPDB Length = 473 Score = 380 bits (975), Expect = e-105, Method: Composition-based stats. Identities = 110/440 (25%), Positives = 176/440 (40%), Gaps = 84/440 (19%) Query: 161 FLVWVTFPLVLILFSALFCHL-------ISPQAVGSGIPEMKTILRGVVLKEYLTMKAFV 213 FL+W PL IL SAL + +P+A GSGIPE++ L L+ + Sbjct: 76 FLLW---PLAFIL-SALLAMVGYFLVRKFAPEAGGSGIPEIEGALE--ELRPVRWWRVLP 129 Query: 214 AKVVALTAGLGSGIPVGKEGPFVHIA-SICAAVLSKFMSVFCGVYEQPYYYSDILTVGCA 272 K + LG+G+ +G+EGP V I ++ VL F +L G A Sbjct: 130 VKFIGGMGTLGAGMVLGREGPTVQIGGNLGRMVLDVFR------MRSAEARHTLLATGAA 183 Query: 273 VGVGCCFGTPLGGVLFSIEVTSTYF-----AVRNYWRGFFAATFSAFVFRVLAVWNKDAV 327 G+ F PL G+LF IE F +++ + G S+ VFR ++N +A Sbjct: 184 AGLSAAFNAPLAGILFIIEEMRPQFRYNLISIKAVFTG---VIMSSIVFR---IFNGEAP 237 Query: 328 TITALFRTNFRMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLA 387 I D P + L + +GI G++G VF L V + + + Q Sbjct: 238 II----EVGKLSDAPVN--TLWLYLILGIIFGVVGPVFNSL-------VLRTQDMFQ--- 281 Query: 388 KHRLLYPGIVTFVIASFTFPPGMGQFMAGELMPREAISTLFDNNTWVKHAGDPESLG--Q 445 +F GE+ + + +P + G Sbjct: 282 ------------------------RFHGGEIKKWVLMGGAIGGLCGILGLIEPAAAGGGF 317 Query: 446 SAVWIHPRVNVVIIIFLF-FVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAM 504 + + I N + + LF F+ + +++ + P G F P+ LG G G A+ Sbjct: 318 NLIPIAAAGNFSVGLLLFIFITRVVTTLLCFSSGAPGGIFAPMLALGTLLGTAFGMAAAV 377 Query: 505 LFPDGILFDDIIYKILPGGYAVIGAAALTGA-VSHTVSTAVICFELTGQIAHILPMMVAV 563 LFP Y + G +A+ G AL A V ++ V+ E+T ILPM++ Sbjct: 378 LFPQ--------YHLEAGTFAIAGMGALMAASVRAPLTGIVLVLEMTDNYQLILPMIITC 429 Query: 564 ILANMVAQSLQPS-LYDSII 582 + A ++AQ L LY +I+ Sbjct: 430 LGATLLAQFLGGKPLYSTIL 449 >3EJY-A nrPDB Length = 473 Score = 275 bits (703), Expect = 6e-74, Method: Composition-based stats. Identities = 100/475 (21%), Positives = 171/475 (36%), Gaps = 73/475 (15%) Query: 119 IFLVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALF 178 ++G L+ L + + D A + + PL V VL +F Sbjct: 37 FMAAVVGTLVGLAAVAFDKGVAWLQNQRMGALVHTADNYPLLLTVAFLCSAVLAMFGYFL 96 Query: 179 CHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHI 238 +P+A GSGIPE++ L + + K LG G+ +G+EGP V I Sbjct: 97 VRKYAPEAGGSGIPEIEGALEDQ--RPVRWWRVLPVKFFGGLGTLGGGMVLGREGPTVQI 154 Query: 239 -ASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYF 297 +I VL F + +L G A G+ F PL G+LF IE F Sbjct: 155 GGNIGRMVLDIFR------LKGDEARHTLLATGAAAGLAAAFNAPLAGILFIIEHMRPQF 208 Query: 298 -----AVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFA 352 +++ + G S ++R ++N + I D P + L + Sbjct: 209 RYTLISIKAVFIG---VIMSTIMYR---IFNHEVALID----VGKLSDAPLN--TLWLYL 256 Query: 353 AIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQ 412 +GI G+ G +F V + L + + Sbjct: 257 ILGIIFGIFGPIFNK-------WVLGMQDL---------------------------LHR 282 Query: 413 FMAGELMPREAISTLFDNNTWVKHAGDPESL--GQSAVWIHPRVNVVIIIFLF-FVMKFW 469 G + + + P + G + + I N + + +F FV + Sbjct: 283 VHGGNITKWVLMGGAIGGLCGLLGFVAPATSGGGFNLIPIATAGNFSMGMLVFIFVARVI 342 Query: 470 MSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGA 529 +++ + P G F P+ LG G G + LFP Y + G +A+ G Sbjct: 343 TTLLCFSSGAPGGIFAPMLALGTVLGTAFGMVAVELFPQ--------YHLEAGTFAIAGM 394 Query: 530 AALTGA-VSHTVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPS-LYDSII 582 AL A + ++ ++ E+T ILPM++ + A ++AQ LY +I+ Sbjct: 395 GALLAASIRAPLTGIILVLEMTDNYQLILPMIITGLGATLLAQFTGGKPLYSAIL 449 >3ND0-A nrPDB Length = 466 Score = 183 bits (465), Expect = 3e-46, Method: Composition-based stats. Identities = 86/469 (18%), Positives = 165/469 (35%), Gaps = 62/469 (13%) Query: 122 VLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCHL 181 +++GL+ ++ LQ + P PL +LV ++ S Sbjct: 36 IVVGLITGVLGAGFKSAVNNMLQWRSQLAQILAPIPPLAWLVTALISGGMVALSFWLMKR 95 Query: 182 ISPQAVGSGIPEMKTILRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHIASI 241 +P GSGIP+++ L G + + + K+V LG+G+ G EGP + + Sbjct: 96 FAPDTSGSGIPQIEGHLEGKL--PLVWQRVLPIKLVGGFLSLGAGMLAGFEGPTIQMGGS 153 Query: 242 CAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVTSTYFAVR- 300 + F E ++ VG G+ F PL GV E F + Sbjct: 154 IGQMTG---GWFKATQENQRI---LIAVGAGAGLATAFNAPLAGVALIGEEMHPRFRSQT 207 Query: 301 -NYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAFAAIGICCG 359 Y F + + R++ + I+ T F+ P D L F +GI G Sbjct: 208 LAYHSLLFGCVMATIILRMI---RGQSAIISL---TEFK-RVPLD--SLWMFIILGILFG 258 Query: 360 LLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGMGQFMAGELM 419 ++G F +V+ + PP ++ Sbjct: 259 VMGYTFNRGLFKVLDWFDR---------------------------LPPLATKWKGF--- 288 Query: 420 PREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVATTMPI 479 + ++ + + + +W + + L F +F ++++ Sbjct: 289 ---LLGSIIGILSLF-PLPLTDGGDNAVLWAFNSQSHFSTLILVFCGRFLLTLICYGSGA 344 Query: 480 PCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTGA-VSH 538 G F P+ + + + +LFP I P A+ G AL A V Sbjct: 345 IGGIFAPMLGIASIVSVAMARHFHLLFPSQIP--------EPAVMAIAGMGALVAATVRA 396 Query: 539 TVSTAVICFELTGQIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKL 587 ++ ++ E+T ILP++V ++A++VA++L +++ + L Sbjct: 397 PLTAILLTIEMTDNYFVILPLLVTCLVASVVAEALGGKPIYTVLLERTL 445 >6D0J-A nrPDB Length = 421 Score = 50.5 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 72/401 (17%), Positives = 131/401 (32%), Gaps = 71/401 (17%) Query: 121 LVLLGLLMALVSWSMDYVSAKSLQAYKWSYAQMQPSLPLQFLVWVTFPLVLILFSALFCH 180 L LL L++ +++ ++D K L + + S L PL+L L C Sbjct: 20 LGLLSLVIGVLAGAVDTFFGKIL----LFLSAFRESHFL--------PLILFLPIIGICF 67 Query: 181 LISPQAVGSGIPEMKTI--LRGVVLKEYLTMKAFVAKVVALTAGLGSGIPVGKEGPFVHI 238 Q G P+ + L G ++ + ++ +V G G+EG V + Sbjct: 68 TYLFQKYGDRSPQGMNLVFLVGQEEEKDIPLRLIPFVMVGTWLTHLFGGSAGREGVAVQL 127 Query: 239 ASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCFGTPLGGVLFSIEVT----- 293 + A L ++ + Y S ++ +G A G F TP+ F++EV Sbjct: 128 GATIANRLGNWVRLEK-------YASTLIMIGMAAGFAGLFETPIAATFFALEVLVIGKF 180 Query: 294 STYFAVRNYWRGFFAATFSAFVFRVLAVWNKDAVTITALFRTNFRMDFPFDLKELPAF-- 351 S + + F A+T S ++ L + + + DL +P F Sbjct: 181 SHHALLPALLAAFTASTTSQWL---------------GLEKFSLMLPQSVDL-TIPVFLK 224 Query: 352 -AAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASFTFPPGM 410 IG+ G++G F + +++ +F + L GI + Sbjct: 225 LLVIGLIFGMVGGSFAGCLETMKRIMKR-----RFP--NPLWRIGIGALALVLLFVLLYQ 277 Query: 411 GQFMAGELMPREAISTLFDNNTWV-----------KHAGDPESLGQSAVWIHPRVNVVII 459 G++ IS F N LG + + + + Sbjct: 278 GRYSGLGTN---LISASFTNQPIYSYDWLLKLVLTVLTISSGFLGGEVTPLFAIGSSLGV 334 Query: 460 IFLFFVMKFWMSIVATTMPIPCG-----GFMPVFVLGAAFG 495 + + A G F P+F+ G FG Sbjct: 335 VLAPLFGLPIELVAALGYASVFGSATSTLFAPIFIGGEVFG 375 >5M95-A nrPDB Length = 415 Score = 37.0 bits (84), Expect = 0.043, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 65/160 (40%), Gaps = 15/160 (9%) Query: 226 GIPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILT--VGCAVGVGCCFGTPL 283 GI GK+ +A + LSK +++ + + + + +G A+ + FG PL Sbjct: 49 GIATGKD-----LAQMTRHFLSKPVAIIFWIIAELAIIATDIAEVIGSAIALDLIFGIPL 103 Query: 284 --GGVLFSIEVTSTYFAVRNYWRGFFAATFSAFVFRVLAVWNKD----AVTITALFRTNF 337 G ++ +V F +R +R A +F VLA++ + + +T + F Sbjct: 104 IVGALITVFDVFLLLFIMRFGFRKI-EAIVGTLIFTVLAIFVFEVFISSPQLTDILN-GF 161 Query: 338 RMDFPFDLKELPAFAAIGICCGLLGAVFVYLHRQVMLGVR 377 + + A+GI + +YLH ++ + Sbjct: 162 VPHKEIVTNQGILYIALGIIGATIMPHNLYLHSSIVQSRK 201 >3V94-A nrPDB Length = 345 Score = 35.5 bits (80), Expect = 0.14, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 38/92 (41%), Gaps = 9/92 (9%) Query: 793 LVDNMSPEEIEAWEQEQLSQPVC-------FDSCCIDQSPFQLVEQTTLHKTH--TLFSL 843 L+++++P E +A L+ VC F + D F+ + TL + H T F L Sbjct: 121 LMEHLTPLECKAAAFAALTHDVCHPGRTNAFLAAVQDPVSFKFSGKGTLEQLHTATAFEL 180 Query: 844 LGLHLAYVTSMGKLRGVLALEELQKAIEGHTK 875 L + TS L + + + GHT Sbjct: 181 LNVTEFDFTSSMDNASFLEFKNIVSHLIGHTD 212 >6GB2-BJ nrPDB Length = 262 Score = 33.2 bits (74), Expect = 0.60, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 43/96 (44%), Gaps = 5/96 (5%) Query: 552 QIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVR 611 + ++LP+ V N++ S +P + + + +K +P+LP LG + + + + Sbjct: 139 KYQNLLPLFV---GHNLLLVSEEPKVKEMVRILKGIPFLPLLGG-CIDDTILSRQGFINY 194 Query: 612 DVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMI 647 K S + GEL L T +T ++ + + Sbjct: 195 S-KLPSLALVQGELVGGLTFLTAQTYSMLQHQPRQL 229 >2YVZ-A nrPDB Length = 278 Score = 32.0 bits (71), Expect = 1.4, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 602 TIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQALL 661 V +IM V +V E+ L+ LP+VD + L+G V ++ +L Sbjct: 198 RTRVAEIMNPKVVYVRTDTDQEEVARLMADYDFTVLPVVD--EEGRLVGIVTVDDVLDVL 255 Query: 662 Q 662 + Sbjct: 256 E 256 >2YVX-A nrPDB Length = 473 Score = 32.0 bits (71), Expect = 1.5, Method: Composition-based stats. Identities = 15/61 (24%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 602 TIFVEDIMVRDVKFVSASYTYGELRTLLQTTTVKTLPLVDSKDSMILLGSVERSELQALL 661 V +IM V +V E+ L+ LP+VD + L+G V ++ +L Sbjct: 218 RTRVAEIMNPKVVYVRTDTDQEEVARLMADYDFTVLPVVD--EEGRLVGIVTVDDVLDVL 275 Query: 662 Q 662 + Sbjct: 276 E 276 >3J9M-I nrPDB Length = 261 Score = 31.2 bits (69), Expect = 2.5, Method: Composition-based stats. Identities = 21/89 (23%), Positives = 40/89 (44%), Gaps = 5/89 (5%) Query: 552 QIAHILPMMVAVILANMVAQSLQPSLYDSIIQVKKLPYLPDLGWNQLSKYTIFVEDIMVR 611 + ++LP+ V NM+ S +P + + + ++ +P+LP LG + + + + Sbjct: 139 KYQNLLPLFV---GHNMLLVSEEPKVKEMVRILRTVPFLPLLGG-CIDDTILSRQGFINY 194 Query: 612 DVKFVSASYTYGELRTLLQTTTVKTLPLV 640 K S GEL L T +T L+ Sbjct: 195 S-KLPSLPLVQGELVGGLTCLTAQTHSLL 222 >3ZUY-A nrPDB Length = 323 Score = 30.1 bits (66), Expect = 5.3, Method: Composition-based stats. Identities = 25/163 (15%), Positives = 64/163 (39%), Gaps = 12/163 (7%) Query: 415 AGELMPREAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFLFFVMKFWMSIVA 474 AG +P + + D ++ HP+V ++ +I F +M +++ Sbjct: 36 AGPYIPW-LLGIIMFGMGLTLKPSD-----FDILFKHPKVVIIGVIAQFAIMPATAWLLS 89 Query: 475 TTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGILFDDIIYKILPGGYAVIGAAALTG 534 + +P + V ++G G +M L ++ + + + + LT Sbjct: 90 KLLNLPAEIAVGVILVGCCPGGTASNVMTYL-----ARGNVALSVAVTSVSTLISPLLTP 144 Query: 535 AVSHTVSTAVICFELTGQIAHILPM-MVAVILANMVAQSLQPS 576 A+ ++ ++ + G + I+ M ++ ++L +V + L Sbjct: 145 AIFLMLAGEMLEIQAAGMLMSIVKMVLLPIVLGLIVHKVLGSK 187 >2AVN-A nrPDB Length = 260 Score = 29.7 bits (65), Expect = 6.0, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 466 MKFWMSIVATTMPIPCGGFMPVFVLGAAFG------RLVGEIMAMLFPDGILFDDIIY 517 +K + A +P P G F V LG + EI +L PDG+L + Sbjct: 97 VKNVVEAKAEDLPFPSGAFEAVLALGDVLSYVENKDKAFSEIRRVLVPDGLLIATVDN 154 >4BWZ-A nrPDB Length = 394 Score = 29.3 bits (64), Expect = 7.9, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 54/158 (34%), Gaps = 13/158 (8%) Query: 168 PLVLILFSALFCHLISPQAVGSGIPEMKTILRGVVLKEYLTMKAFV-AKVVALTAGLGSG 226 L+ S + + P + IL V+ + L + VA T + G Sbjct: 120 GTALVATSVGITARVLQELGVLSRPYSRIILGAAVIDDVLGLIVLACVNGVAETGQVEVG 179 Query: 227 -------IPVGKEGPFVHIASICAAVLSKFMSVFCGVYEQPYYYSDILTVGCAVGVGCCF 279 + V G V ++++ A + + + V + + + ++G+ Sbjct: 180 AITRLIVLSVVFVGLAVFLSTLIARLPLERLPVGSPLGFALALGVGMAALAASIGLAPIV 239 Query: 280 GTPLGGVLFS-----IEVTSTYFAVRNYWRGFFAATFS 312 G LGG+L S + FA+ ++ F A Sbjct: 240 GAFLGGMLLSEVREKYRLEEPIFAIESFLAPIFFAMVG 277 >4HE8-N nrPDB Length = 427 Score = 29.3 bits (64), Expect = 9.6, Method: Composition-based stats. Identities = 46/242 (19%), Positives = 72/242 (29%), Gaps = 23/242 (9%) Query: 346 KELPAFAAIGICCGLLGAVFVYLHRQVMLGVRKHKALSQFLAKHRLLYPGIVTFVIASF- 404 + A +G + + + L V LA R L +V S Sbjct: 60 QVFTLLALLGALWTV--GLVRSGRFEFYLLVLYAALGMHLLASTRHLLLMLVALEALSLP 117 Query: 405 -----TFPPGMG------QFMAGELMPREAIST--LFDNNTWVKHAGDPESLGQSAVWIH 451 T+ G G F+ G L + LF T G P A+ + Sbjct: 118 LYALATWRRGQGLEAALKYFLLGALAAAFFLYGAALFYGATGSLVLGAPGEGPLYALALG 177 Query: 452 PRVNVVIIIFLFFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFPDGIL 511 + + FW V P P FM V AAF L + + P L Sbjct: 178 LLLVGLGFKAALAPFHFWTPDVYQGSPTPVVLFMATSVKAAAFAAL----LRVAAPPEAL 233 Query: 512 FDDIIYKILPGGYAVIG---AAALTGAVSHTVSTAVICFELTGQIAHILPMMVAVILANM 568 + ++ G A + A L S + + TG + ++ +LA Sbjct: 234 ALLVALSVVVGNLAALAQKEAKRLLAYSSIAHAGYMALALYTGNAQALGFYLLTYVLATG 293 Query: 569 VA 570 +A Sbjct: 294 LA 295 >3CLL-A nrPDB Length = 300 Score = 28.9 bits (63), Expect = 9.9, Method: Composition-based stats. Identities = 32/165 (19%), Positives = 54/165 (32%), Gaps = 12/165 (7%) Query: 407 PPGMGQFMAGELMPR----EAISTLFDNNTWVKHAGDPESLGQSAVWIHPRVNVVIIIFL 462 PP F GEL AI+ ++ + V ++ I + Sbjct: 40 PPPAPFFDLGELKLWSFWRAAIAEFIATLLFLYITVATVIGHSKETVVCGSVGLLGIAWA 99 Query: 463 FFVMKFWMSIVATTMPIPCGGFMPVFVLGAAFGRLVGEIMAMLFP-----DGILFDDIIY 517 F M F + T I G P G R V + A+++ I ++ Sbjct: 100 FGGMIFVLVYC--TAGISGGHINPAVTFGLFLARKVELLRALVYMIAQCLGAICGVGLVK 157 Query: 518 KILPGGYAVIGAAALTGAVSHTVSTAVICFELTGQIAHILPMMVA 562 + G Y G A + A+ + TA+ E+ G + + A Sbjct: 158 AFMKGPYNQFGGGANSVALGYNKGTALGA-EIIGTFVLVYTVFSA 201 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.315 0.130 0.356 Lambda K H 0.267 0.0400 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 38,080,916 Number of Sequences: 36641 Number of extensions: 1599498 Number of successful extensions: 4048 Number of sequences better than 10.0: 29 Number of HSP's better than 10.0 without gapping: 16 Number of HSP's successfully gapped in prelim test: 32 Number of HSP's that attempted gapping in prelim test: 3944 Number of HSP's gapped (non-prelim): 85 length of query: 988 length of database: 10,336,785 effective HSP length: 107 effective length of query: 881 effective length of database: 6,416,198 effective search space: 5652670438 effective search space used: 5652670438 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 64 (29.3 bits)