BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P35270 (261 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4HWK-A nrPDB 523 e-149 4Z3K-A nrPDB 521 e-149 1OAA-A nrPDB 394 e-110 3KZV-A nrPDB 83 1e-16 1GEE-A nrPDB 66 2e-11 3EMK-A nrPDB 59 2e-09 3AUT-A nrPDB 57 6e-09 3RKU-A nrPDB 57 1e-08 2PNF-A nrPDB 55 3e-08 1CYD-A nrPDB 54 6e-08 1Q7C-A nrPDB 53 1e-07 4CQM-B nrPDB 53 1e-07 1HXH-A nrPDB 52 2e-07 2C07-A nrPDB 52 3e-07 4BO1-A nrPDB 52 3e-07 3D3W-A nrPDB 52 4e-07 2B4Q-A nrPDB 52 4e-07 3WOH-A nrPDB 51 5e-07 3OIC-A nrPDB 49 2e-06 2AE2-A nrPDB 49 2e-06 3ZV3-A nrPDB 49 2e-06 5CDY-A nrPDB 49 2e-06 3R3S-A nrPDB 49 3e-06 5T5Q-A nrPDB 48 4e-06 2GDZ-A nrPDB 48 4e-06 4IIN-A nrPDB 48 5e-06 4DA9-A nrPDB 48 5e-06 3GRP-A nrPDB 48 5e-06 3RSH-A nrPDB 47 7e-06 2CFC-A nrPDB 46 1e-05 2UVD-A nrPDB 46 2e-05 6CI9-A nrPDB 46 2e-05 5IZ4-A nrPDB 45 4e-05 3O4R-A nrPDB 44 6e-05 2ZAT-A nrPDB 44 1e-04 3V2G-A nrPDB 43 1e-04 2X9N-A nrPDB 42 3e-04 3F9I-A nrPDB 42 3e-04 3LYL-A nrPDB 42 4e-04 3DWF-A nrPDB 42 4e-04 1K2W-A nrPDB 41 5e-04 3FTP-A nrPDB 41 5e-04 2CDH-G nrPDB 41 5e-04 4MOW-A nrPDB 41 6e-04 1AE1-A nrPDB 40 8e-04 4RZH-A nrPDB 40 9e-04 1SNY-A nrPDB 40 0.001 3U5T-A nrPDB 39 0.002 3WTC-A nrPDB 39 0.002 4HBG-A nrPDB 39 0.003 3OEC-A nrPDB 39 0.003 4E6P-A nrPDB 39 0.003 5PGZ-A nrPDB 38 0.003 4DRY-A nrPDB 37 0.008 1GEG-A nrPDB 36 0.018 1AHH-A nrPDB 36 0.022 4JRO-A nrPDB 35 0.024 5OJG-A nrPDB 35 0.025 2HQ1-A nrPDB 35 0.029 3E9N-A nrPDB 35 0.042 4K6F-A nrPDB 34 0.069 2FWM-X nrPDB 34 0.074 3WYE-A nrPDB 33 0.086 5YSS-A nrPDB 33 0.086 5TQV-A nrPDB 33 0.10 5ILO-A nrPDB 33 0.12 4IS3-A nrPDB 33 0.13 6NRP-A nrPDB 33 0.15 3RWB-A nrPDB 33 0.16 1O5I-A nrPDB 33 0.16 4M8S-A nrPDB 32 0.22 1E3W-A nrPDB 32 0.23 4CQL-A nrPDB 32 0.27 1DOH-A nrPDB 32 0.29 4NBT-A nrPDB 31 0.60 4DMM-A nrPDB 31 0.67 2HRB-A nrPDB 30 0.73 5U9P-A nrPDB 30 0.81 4GKB-A nrPDB 30 0.84 4AVY-A nrPDB 30 1.1 3G8Q-A nrPDB 30 1.3 1NFF-A nrPDB 30 1.4 2O23-A nrPDB 29 1.8 4FC7-A nrPDB 29 1.8 3OSU-A nrPDB 29 2.0 2N03-A nrPDB 29 2.1 2PH3-A nrPDB 29 2.6 2QHX-A nrPDB 28 2.9 2BFA-A nrPDB 28 3.2 4HP8-A nrPDB 28 3.7 1P33-A nrPDB 28 4.6 3O26-A nrPDB 28 4.8 3A28-C nrPDB 28 4.9 3U9L-A nrPDB 28 5.6 3U2O-A nrPDB 27 6.7 1UUO-A nrPDB 27 9.5 >4HWK-A nrPDB Length = 288 Score = 523 bits (1348), Expect = e-149, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG Sbjct: 28 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 87 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV Sbjct: 88 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 147 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML Sbjct: 148 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 207 Query: 181 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK Sbjct: 208 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 267 Query: 241 LLSLLEKDEFKSGAHVDFYDK 261 LLSLLEKDEFKSGAHVDFYDK Sbjct: 268 LLSLLEKDEFKSGAHVDFYDK 288 >4Z3K-A nrPDB Length = 275 Score = 521 bits (1343), Expect = e-149, Method: Compositional matrix adjust. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG Sbjct: 15 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 74 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV Sbjct: 75 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 134 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML Sbjct: 135 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 194 Query: 181 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK Sbjct: 195 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 254 Query: 241 LLSLLEKDEFKSGAHVDFYDK 261 LLSLLEKDEFKSGAHVDFYDK Sbjct: 255 LLSLLEKDEFKSGAHVDFYDK 275 >1OAA-A nrPDB Length = 259 Score = 394 bits (1011), Expect = e-110, Method: Compositional matrix adjust. Identities = 192/257 (74%), Positives = 224/257 (87%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 GLG AVC+LTGASRGFGR LAP LA LLSPGSV+++SAR++ LRQL+ ELGA++ L+V Sbjct: 3 GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKV 62 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V ADLG EAG+Q+LL A+RELPRP+GLQRLLLINNA +LGDVSKGF++++D +VNNY Sbjct: 63 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 122 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 WALNLTSMLCLTS L AF DSPGL++TVVNISSLCALQP+KGW LYCAGKAARDML+QV Sbjct: 123 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 182 Query: 184 LALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 LA EEP+VRVL+YAPGPLD DMQQLARETS DP++R LQ+LK+ G LVDC SAQKLL Sbjct: 183 LAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLG 242 Query: 244 LLEKDEFKSGAHVDFYD 260 LL+KD F+SGAHVDFYD Sbjct: 243 LLQKDTFQSGAHVDFYD 259 >3KZV-A nrPDB Length = 254 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 74/235 (31%), Positives = 112/235 (47%), Gaps = 21/235 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TG SRG G+++ +L SL +V+ AR++ L++L+ E+ G R V Sbjct: 4 VILVTGVSRGIGKSIVDVLFSL-DKDTVVYGVARSEAPLKKLK-----EKYGDRFFYVVG 57 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ ++ L+QL+ A KG ++ L+ NAG L V + VN + L Sbjct: 58 DITEDSVLKQLVNA-----AVKGHGKIDSLVANAGVLEPVQN-----VNEIDVNAWKKLY 107 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 + + S V A P+ N VV +SS F W Y + KAA + LA E Sbjct: 108 DINFFSIVSLVGIALPELKKTNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLANE 167 Query: 188 EPNVRVLNYAPGPLDTDMQQLARE----TSVDPDMRKGLQELKAKGKLVDCKVSA 238 E V+ + APG +DTDMQ RE +S+ + K + LK +L+D V A Sbjct: 168 ERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPA 222 >1GEE-A nrPDB Length = 261 Score = 65.9 bits (159), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 61/226 (26%), Positives = 109/226 (48%), Gaps = 19/226 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG+S G G+++A A+ + V+ ++ DEA LE ++ G + V Sbjct: 9 VVVITGSSTGLGKSMAIRFATEKAK-VVVNYRSKEDEANSVLEE---IKKVGGEAIAVKG 64 Query: 69 DLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ E+ + L+ A++E + ++INNAG VS + LSD +V + N Sbjct: 65 DVTVESDVINLVQSAIKEFGKLD-----VMINNAGLENPVSSHEMSLSDWNKVID---TN 116 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 LT + +K F ++ + TV+N+SS+ P+ + Y A K ++ + LALE Sbjct: 117 LTGAFLGSREAIKYFVEND-IKGTVINMSSVHEKIPWPLFVHYAASKGGMKLMTETLALE 175 Query: 188 EP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKL 231 +RV N PG ++T + E DP+ R ++ + G + Sbjct: 176 YAPKGIRVNNIGPGAINTPINA---EKFADPEQRADVESMIPMGYI 218 >3EMK-A nrPDB Length = 246 Score = 58.9 bits (141), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/211 (30%), Positives = 97/211 (45%), Gaps = 19/211 (9%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TGA+ G G +A +L + G+++ L +E L++L AELG R+ PA+ Sbjct: 10 ALVTGATGGLGEAIAR---ALHAQGAIVGLHGTREEKLKELAAELGE-----RIFVFPAN 61 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 L ++ L E G+ +L+NNAG D FV +SD + +NLT Sbjct: 62 LSDREAVKALGQKAEE--EMGGVD--ILVNNAGITRDGL--FVRMSDEDW-DAVLTVNLT 114 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 S+ LT + P N ++NI+S+ + G A YCA KA + LA E Sbjct: 115 SVFNLTREL--THPMMRRRNGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSLAQEIA 172 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDM 218 NV V APG +++ M E D M Sbjct: 173 SRNVTVNCIAPGFIESAMTGKLNEKQKDAIM 203 >3AUT-A nrPDB Length = 269 Score = 57.4 bits (137), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 57/226 (25%), Positives = 101/226 (44%), Gaps = 19/226 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG S G GR +A V++ N+E L+A+ E +G + + V Sbjct: 17 VVVITGGSTGLGRAMAVRFGQ--EEAKVVINYYNNEE--EALDAKKEVEEAGGQAIIVQG 72 Query: 69 DLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ E + L+ A++E ++INNAG V + L + +V + N Sbjct: 73 DVTKEEDVVNLVQTAIKEFGTLD-----VMINNAGVENPVPSHELSLDNWNKVID---TN 124 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 LT + +K F ++ + V+N+SS+ + P+ + Y A K ++ + LALE Sbjct: 125 LTGAFLGSREAIKYFVEND-IKGNVINMSSVHEMIPWPLFVHYAASKGGMKLMTETLALE 183 Query: 188 EP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKL 231 +RV N PG ++T + E DP R ++ + G + Sbjct: 184 YAPKGIRVNNIGPGAMNTPINA---EKFADPVQRADVESMIPMGYI 226 >3RKU-A nrPDB Length = 287 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 53/205 (25%), Positives = 95/205 (46%), Gaps = 14/205 (6%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L + L+TGAS G G+ A + L+L+AR E L +L+ + E +V Sbjct: 31 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVH 90 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAG-SLGDVSKGFVDLSDSTQVNN 122 D+ ++ + L P+ + + +L+NNAG +LG G + D + + Sbjct: 91 VAQLDITQAEKIKPFIENL-----PQEFKDIDILVNNAGKALGSDRVGQIATED---IQD 142 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 + N+T+++ +T +VL F + +VN+ S+ + ++YCA K A Sbjct: 143 VFDTNVTALINITQAVLPIFQAKNSGD--IVNLGSIAGRDAYPTGSIYCASKFAVGAFTD 200 Query: 183 VLALEEPN--VRVLNYAPGPLDTDM 205 L E N +RV+ APG ++T+ Sbjct: 201 SLRKELINTKIRVILIAPGLVETEF 225 >2PNF-A nrPDB Length = 248 Score = 55.1 bits (131), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 66/216 (30%), Positives = 102/216 (47%), Gaps = 21/216 (9%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 ME L V L+TG++RG GR +A LA S GS ++++ + E + + E+ A + G Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLA---SAGSTVIITGTSGERAKAVAEEI-ANKYG 56 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLS--DST 118 ++ V +L +E + + + L G+ +L+NNAG D K F+ +S D Sbjct: 57 VKAHGVEMNLLSEESINKAFEEIYNL--VDGID--ILVNNAGITRD--KLFLRMSLLDWE 110 Query: 119 QVNNYWALNLTSMLCLT-SSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAAR 177 +V +NLT +T +S+ K G +VNISS+ G Y KA Sbjct: 111 EV---LKVNLTGTFLVTQNSLRKMIKQRWG---RIVNISSVVGFTGNVGQVNYSTTKAGL 164 Query: 178 DMLFQVLALEEP--NVRVLNYAPGPLDTDMQQLARE 211 + LA E NV V APG ++TDM + E Sbjct: 165 IGFTKSLAKELAPRNVLVNAVAPGFIETDMTAVLSE 200 >1CYD-A nrPDB Length = 244 Score = 53.9 bits (128), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 64/239 (26%), Positives = 112/239 (46%), Gaps = 28/239 (11%) Query: 10 CLLTGASRGFGR-TLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 L+TGA +G GR T+ L AS G+ +V R + L L E G+ V V Sbjct: 10 ALVTGAGKGIGRDTVKALHAS----GAKVVAVTRTNSDL----VSLAKECPGIEPVCV-- 59 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 DLG ++ LG + + LL+NNA + + + F++++ + +++NL Sbjct: 60 DLGDWDATEKALGGIGPVD--------LLVNNAALV--IMQPFLEVTKEA-FDRSFSVNL 108 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 S+ ++ V + + G+ ++VN+SS+ A F Y + K A ML + +A+E Sbjct: 109 RSVFQVSQMVARDMINR-GVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTMLTKAMAMEL 167 Query: 188 -EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 +RV + P + TDM ++ S DP+ + L+E K + + +L LL Sbjct: 168 GPHKIRVNSVNPTVVLTDM---GKKVSADPEFARKLKERHPLRKFAEVEDVVNSILFLL 223 >1Q7C-A nrPDB Length = 244 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 65/244 (26%), Positives = 114/244 (46%), Gaps = 27/244 (11%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV-VRVP 67 + L+TGASRG GR +A LA + G+ ++ +A ++ + + LGA GL + V P Sbjct: 7 IALVTGASRGIGRAIAETLA---ARGAKVIGTATSENGAQAISDYLGANGKGLMLNVTDP 63 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 A + E+ L+++ E+ +L+NNAG D + + D + N+ N Sbjct: 64 ASI--ESVLEKIRAEFGEVD--------ILVNNAGITRD--NLLMRMKDE-EWNDIIETN 110 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 L+S+ L+ +V++A + ++ I S+ G A + A KA + LA E Sbjct: 111 LSSVFRLSKAVMRAMMKKR--HGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLARE 168 Query: 188 EPN--VRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 + + V APG ++TDM + ++ D R G+ G+L + A ++ L Sbjct: 169 VASRGITVNVVAPGFIETDMTR-----ALSDDQRAGILAQVPAGRLGGAQEIANA-VAFL 222 Query: 246 EKDE 249 DE Sbjct: 223 ASDE 226 >4CQM-B nrPDB Length = 244 Score = 52.8 bits (125), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 54/212 (25%), Positives = 90/212 (42%), Gaps = 19/212 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 VC + G SRG GR +A L+A G L + ARN E + +LG + + Sbjct: 11 VCAVFGGSRGIGRAVAQLMA---RKGYRLAVIARNLEGAKAAAGDLGGDH-----LAFSC 62 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ E +Q EL + G L+N AG D G + + + + + NL Sbjct: 63 DVAKEHDVQN---TFEELEKHLGRVN-FLVNAAGINRD---GLLVRTKTEDMVSQLHTNL 115 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 + + ++ G ++VN+ S+ L+ G ++Y A K + LA E Sbjct: 116 LGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKEV 173 Query: 188 -EPNVRVLNYAPGPLDTDMQQLARETSVDPDM 218 +RV APG + TDM + +E + ++ Sbjct: 174 ARKKIRVNVVAPGFVHTDMTKDLKEEHLKKNI 205 >1HXH-A nrPDB Length = 253 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 64/216 (29%), Positives = 105/216 (48%), Gaps = 26/216 (12%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TG + G G + LL L G+ + S N+ A +QL AELG ERS + V Sbjct: 8 VALVTGGASGVGLEVVKLL---LGEGAKVAFSDINEAAGQQLAAELG-ERS----MFVRH 59 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVNNYWAL 126 D+ +EA ++ A++ R L +L+NNAG L GD+ G L D +++ + Sbjct: 60 DVSSEADWTLVMAAVQR--RLGTLN--VLVNNAGILLPGDMETG--RLEDFSRL---LKI 110 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 N S+ + A ++ G +++N++S+ + P + +A Y A KAA L + AL Sbjct: 111 NTESVFIGCQQGIAAMKETGG---SIINMASVSSWLPIEQYAGYSASKAAVSALTRAAAL 167 Query: 187 ----EEPNVRVLNYAPGPLDTDMQQLARETSVDPDM 218 + +RV + P + T M Q + V +M Sbjct: 168 SCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEM 203 >2C07-A nrPDB Length = 285 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 57/211 (27%), Positives = 93/211 (44%), Gaps = 28/211 (13%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGA RG GR +A +LA +S + + ++ +++ G E SG Sbjct: 46 VALVTGAGRGIGREIAKMLAKSVSHVICISRTQKSCDSVVDEIKSFGYESSGY-----AG 100 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA--- 125 D+ + + +++ + L K + +L+NNAG D F+ + N+ W Sbjct: 101 DVSKKEEISEVINKI--LTEHKNVD--ILVNNAGITRD--NLFLRMK-----NDEWEDVL 149 Query: 126 -LNLTSMLCLTSSVLKAFPDSPGLNRT--VVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 NL S+ +T + K + NR ++NISS+ L G A Y + KA + Sbjct: 150 RTNLNSLFYITQPISKRMIN----NRYGRIINISSIVGLTGNVGQANYSSSKAGVIGFTK 205 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARE 211 LA E N+ V APG + +DM E Sbjct: 206 SLAKELASRNITVNAIAPGFISSDMTDKISE 236 >4BO1-A nrPDB Length = 269 Score = 51.6 bits (122), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 61/204 (29%), Positives = 97/204 (47%), Gaps = 22/204 (10%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAEL---GAERSGLRVVR 65 V L+TGASRG G+ +A L L G+V++ +A + ++ L G E +GL V+ Sbjct: 29 VALVTGASRGIGQAIALELGRL---GAVVIGTATSASGAEKIAETLKANGVEGAGL-VLD 84 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 V +D A L+ + + L +P L+++NNAG D V + D + Sbjct: 85 VSSDESVAATLEHI---QQHLGQP-----LIVVNNAGITRD--NLLVRMKDDEWF-DVVN 133 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 NL S+ L+ +VL+ + R ++NI S+ G Y A KA + + LA Sbjct: 134 TNLNSLYRLSKAVLRGMTKAR-WGR-IINIGSVVGAMGNAGQTNYAAAKAGLEGFTRALA 191 Query: 186 LEEPN--VRVLNYAPGPLDTDMQQ 207 E + + V APG +DTDM + Sbjct: 192 REVGSRAITVNAVAPGFIDTDMTR 215 >3D3W-A nrPDB Length = 244 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 66/242 (27%), Positives = 113/242 (46%), Gaps = 27/242 (11%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 GR V L+TGA +G GR + +L + G+ +V +R L L E G+ V Sbjct: 7 GRRV-LVTGAGKGIGRGT---VQALHATGARVVAVSRTQADLDSLVREC----PGIEPVC 58 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 V DLG ++ LG++ + LL+NNA + + F++++ + + Sbjct: 59 V--DLGDWEATERALGSVGPVD--------LLVNNAAV--ALLQPFLEVTKEA-FDRSFE 105 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 +NL +++ ++ V + + G+ +VN+SS C+ + ++YC+ K A DML +V+A Sbjct: 106 VNLRAVIQVSQIVARGL-IARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDMLTKVMA 164 Query: 186 LE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 LE +RV P + T M Q T DP K + GK + + +L Sbjct: 165 LELGPHKIRVNAVNPTVVMTSMGQ---ATWSDPHKAKTMLNRIPLGKFAEVEHVVNAILF 221 Query: 244 LL 245 LL Sbjct: 222 LL 223 >2B4Q-A nrPDB Length = 276 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 68/220 (30%), Positives = 99/220 (45%), Gaps = 33/220 (15%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 + L+TG SRG G+ +A LL G+ + + AR+ EA L A +PA Sbjct: 31 IALVTGGSRGIGQMIA---QGLLEAGARVFICARDAEACADTATRLSAYGD---CQAIPA 84 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 DL +EAG ++L AL EL RL +L+NNAG+ + +S +V LN Sbjct: 85 DLSSEAGARRLAQALGELS-----ARLDILVNNAGTSWGAALESYPVSGWEKVMQ---LN 136 Query: 128 LTSMLCLTSSVL-----KAFPDSPGLNRTVVNISSLCALQPFKGWAL-YCAGKAARDMLF 181 +TS+ +L A ++P V+NI S+ + A Y KAA L Sbjct: 137 VTSVFSCIQQLLPLLRRSASAENPA---RVINIGSVAGISAMGEQAYAYGPSKAALHQLS 193 Query: 182 QVLAL----EEPNVRVLNYAPGPLDTDMQQLARETSVDPD 217 ++LA E NV V+ APG + M R + DP Sbjct: 194 RMLAKELVGEHINVNVI--APGRFPSRMT---RHIANDPQ 228 >3WOH-A nrPDB Length = 251 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 59/210 (28%), Positives = 93/210 (44%), Gaps = 21/210 (10%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G L V L+TG SRG GR +A LA +V ++ +D + ++ + E+ ER G Sbjct: 7 GALSGKVALVTGGSRGLGRAMALRLAR--DGAAVAIVYVSDDSSAKETQGEI--ERLGGT 62 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 D+ + + + A+ P +L+NNAG + D L+ S + + Sbjct: 63 ARSYRCDVSDAEQVTRCVKAVTADLGPVD----ILVNNAGIIRD------GLAASIKDED 112 Query: 123 YWAL---NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 Y A+ NL + F + +++NISS+ + G A Y + KA Sbjct: 113 YDAVMNTNLKGAFLFIKACYFGFIRKR--SGSIINISSVSGVFGSAGQANYASAKAGLIG 170 Query: 180 LFQVLALE--EPNVRVLNYAPGPLDTDMQQ 207 L + +A E E NVR APG + TDM Q Sbjct: 171 LTKSIAKELAERNVRCNAVAPGLIATDMTQ 200 >3OIC-A nrPDB Length = 258 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 53/200 (26%), Positives = 104/200 (52%), Gaps = 21/200 (10%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG+SRG G+ A LA + ++++ AR+ +A + E+ E+ G++V+ V A+ Sbjct: 7 ALVTGSSRGVGKAAAIRLAE--NGYNIVINYARSKKAALETAEEI--EKLGVKVLVVKAN 62 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 +G A ++++ + E RL + +NNA S V + ++L ++ + W +N+ Sbjct: 63 VGQPAKIKEMFQQIDET-----FGRLDVFVNNAAS--GVLRPVMELEET---HWDWTMNI 112 Query: 129 TS--MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 + +L K + G + +V+ISSL +++ + + KAA + L + LA+ Sbjct: 113 NAKALLFCAQEAAKLMEKNGGGH--IVSISSLGSIRYLENYTTVGVSKAALEALTRYLAV 170 Query: 187 E-EPNVRVLN-YAPGPLDTD 204 E P ++N + G +DTD Sbjct: 171 ELSPKQIIVNAVSGGAIDTD 190 >2AE2-A nrPDB Length = 260 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 66/221 (29%), Positives = 100/221 (45%), Gaps = 26/221 (11%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS-GLRVVRVPAD 69 L+TG SRG G + LASL G+ + +RN ++L L RS G +V D Sbjct: 13 LVTGGSRGIGYGIVEELASL---GASVYTCSRNQ---KELNDCLTQWRSKGFKVEASVCD 66 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAG-SLGDVSKGFV--DLSDSTQVNNYWAL 126 L + + Q+L+ + K +L+NNAG + +K + D S +N A Sbjct: 67 LSSRSERQELMNTVANHFHGK---LNILVNNAGIVIYKEAKDYTVEDYSLIMSINFEAAY 123 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 +L+ L LKA VV ISS+ A+Y A K A D L + LA Sbjct: 124 HLS---VLAHPFLKASERG-----NVVFISSVSGALAVPYEAVYGATKGAMDQLTRCLAF 175 Query: 187 E--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQEL 225 E + N+RV PG + T + ++ T DP+ ++ L +L Sbjct: 176 EWAKDNIRVNGVGPGVIATSLVEM---TIQDPEQKENLNKL 213 >3ZV3-A nrPDB Length = 281 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 20/202 (9%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TG + G GR L + ++ G+ + + ++ E LR+LE G G+ V V + Sbjct: 7 VALITGGASGLGRAL---VDRFVAEGARVAVLDKSAERLRELEVAHGGNAVGV-VGDVRS 62 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDS---TQVNNYWA 125 + ++ L A ++ LI NAG + D S DL + ++ + Sbjct: 63 LQDQKRAAERCLAAFGKIDT--------LIPNAG-IWDYSTALADLPEDKIDAAFDDIFH 113 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 +N+ + + L A S G +VV S P G LY A K A L + +A Sbjct: 114 VNVKGYIHAVKACLPALVSSRG---SVVFTISNAGFYPNGGGPLYTATKHAVVGLVRQMA 170 Query: 186 LE-EPNVRVLNYAPGPLDTDMQ 206 E P+VRV APG ++TD++ Sbjct: 171 FELAPHVRVNGVAPGGMNTDLR 192 >5CDY-A nrPDB Length = 244 Score = 48.5 bits (114), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 65/244 (26%), Positives = 107/244 (43%), Gaps = 27/244 (11%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 + L+TGASRG GR +A L L+ G+ ++ +A +++ + A LG GL + V Sbjct: 7 IALVTGASRGIGRAIAEL---LVERGACVIGTATSEKGAEAISAYLGENGKGLMLNVVD- 62 Query: 69 DLGAEAGLQQLLGALR-ELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 + +L +R E +L+NNAG D + + D + + N Sbjct: 63 ----PTSIDTVLATIRAEFGEVD-----ILVNNAGITRD--NLLMRMKDD-EWQDIIDTN 110 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 LTS+ L+ +V++A R ++ I S+ G Y A KA + LA E Sbjct: 111 LTSVFRLSKAVMRAMMKKR-FGR-IITIGSVVGTMGNAGQVNYAAAKAGVIGFSKSLARE 168 Query: 188 EPN--VRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 + + V APG ++TDM + ++ D R G+ +L D K A ++ L Sbjct: 169 VASRGITVNVVAPGFIETDMTR-----TLTDDQRAGILAQVPANRLGDAKEIASA-VAFL 222 Query: 246 EKDE 249 DE Sbjct: 223 ASDE 226 >3R3S-A nrPDB Length = 294 Score = 48.5 bits (114), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 59/202 (29%), Positives = 93/202 (46%), Gaps = 21/202 (10%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG G GR A A + ++ L A ++A +Q++A + E G + V +P D Sbjct: 52 ALVTGGDSGIGRAAAIAYAREGADVAINYLPAEEEDA-QQVKALI--EECGRKAVLLPGD 108 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 L E+ + L+ RE GL L L+ AG + + DL+ S Q +A+N+ Sbjct: 109 LSDESFARSLVHKAREAL--GGLDILALV--AGKQTAIPE-IKDLT-SEQFQQTFAVNVF 162 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAA-----RDMLFQVL 184 ++ +T + P +++ SS+ A QP Y A KAA R + QV Sbjct: 163 ALFWITQEAIPLLPK----GASIITTSSIQAYQPSPHLLDYAATKAAILNYSRGLAKQVA 218 Query: 185 ALEEPNVRVLNYAPGPLDTDMQ 206 E +RV APGP+ T +Q Sbjct: 219 ---EKGIRVNIVAPGPIWTALQ 237 >5T5Q-A nrPDB Length = 247 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 57/211 (27%), Positives = 98/211 (46%), Gaps = 18/211 (8%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 +LTGA+ G GR +A L + G+ LVL+ + E L A LG+ R+ + AD Sbjct: 13 VLTGANGGIGRAIAELFH---ASGANLVLTDLDREGLDAFAASLGSPE---RIATIKADA 66 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 + ++ + E R G+ L+ +AG +K F ++SD+ + ++NL Sbjct: 67 SSADDAEKTVALAME--RFGGID--FLVPSAGIYQ--AKPFAEMSDA-DWHRTISINLDG 119 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-EP 189 + L L A + + ++V ++SL A + A Y A K A + + L+ E P Sbjct: 120 VFYLCKRALPALKE----DSSIVTLASLAAYRGAYVNAHYGATKGAMVSMTRALSRELAP 175 Query: 190 NVRVLNYAPGPLDTDMQQLARETSVDPDMRK 220 RV +PG ++T M +T +D M + Sbjct: 176 KTRVNGVSPGIIETPMTSELLKTRMDETMTQ 206 >2GDZ-A nrPDB Length = 267 Score = 47.8 bits (112), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 63/249 (25%), Positives = 112/249 (44%), Gaps = 28/249 (11%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGA++G GR A +LL G+ + L N EA Q +A L + + + + Sbjct: 9 VALVTGAAQGIGRAFAE---ALLLKGAKVALVDWNLEAGVQCKAALHEQFEPQKTLFIQC 65 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ A QQL R++ G RL +L+NNAG +++ +N Sbjct: 66 DV---ADQQQLRDTFRKVVDHFG--RLDILVNNAG-----------VNNEKNWEKTLQIN 109 Query: 128 LTSMLCLTSSVLKAFP-DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 L S++ T L + G ++N+SSL L P +YCA K + AL Sbjct: 110 LVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVGFTRSAAL 169 Query: 187 E----EPNVRVLNYAPGPLDTD-MQQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQ 239 VR+ PG ++T ++ + +E ++ + + ++++ ++D + A Sbjct: 170 AANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGILDPPLIAN 229 Query: 240 KLLSLLEKD 248 L++L+E D Sbjct: 230 GLITLIEDD 238 >4IIN-A nrPDB Length = 271 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 90/203 (44%), Gaps = 23/203 (11%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSAR-NDEALRQLEAELGAERSGLRVVRVPA 68 L+TGAS+G G +A LAS+ G + ++ R N E L+ EL E G + + Sbjct: 32 VLITGASKGIGAEIAKTLASM---GLKVWINYRSNAEVADALKNEL--EEKGYKAAVIKF 86 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL-- 126 D +E+ + A++ + + G L+NNAG + D L+ + ++ + Sbjct: 87 DAASES---DFIEAIQTIVQSDG-GLSYLVNNAGVVRD------KLAIKMKTEDFHHVID 136 Query: 127 -NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 NLTS LK S +VVN++S+ + G Y A K + + A Sbjct: 137 NNLTSAFIGCREALKVMSKSRF--GSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFA 194 Query: 186 LEEP--NVRVLNYAPGPLDTDMQ 206 E N+R + PG ++TDM Sbjct: 195 YEGALRNIRFNSVTPGFIETDMN 217 >4DA9-A nrPDB Length = 280 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 50/156 (32%), Positives = 71/156 (45%), Gaps = 12/156 (7%) Query: 56 AERSGL--RVVRVPADLGAEAGLQQLLGAL-RELPRPKGLQRLLLINNAGSLGDVSKGFV 112 AE SGL RV+ + ADL + Q + A+ E R L+NNAG V F+ Sbjct: 72 AELSGLGARVIFLRADLADLSSHQATVDAVVAEFGRID-----CLVNNAGIASIVRDDFL 126 Query: 113 DLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPG-LNRTVVNISSLCALQPFKGWALYC 171 DL + +NL + T +VLKA S +R+++NI+S+ A+ YC Sbjct: 127 DLKPE-NFDTIVGVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYC 185 Query: 172 AGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDM 205 KA Q LAL E + V PG + +DM Sbjct: 186 MSKAGLAAFSQGLALRLAETGIAVFEVRPGIIRSDM 221 >3GRP-A nrPDB Length = 266 Score = 47.8 bits (112), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 56/202 (27%), Positives = 96/202 (47%), Gaps = 27/202 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TGA+ G G +A + G+++ L ++ L+++ A+LG + V A+ Sbjct: 30 ALVTGATGGIGEAIARCFHA---QGAIVGLHGTREDKLKEIAADLGKD-----VFVFSAN 81 Query: 70 LGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 L ++QL A RE+ +G+ +L+NNAG D FV + D ++ A+NL Sbjct: 82 LSDRKSIKQLAEVAEREM---EGID--ILVNNAGITRD--GLFVRMQDQDW-DDVLAVNL 133 Query: 129 TSMLCLTSSVLKAFPDSPGLNRT---VVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 T+ LT ++ + + R ++NI+S+ + G YCA KA + LA Sbjct: 134 TAASTLTRELIHSM-----MRRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKALA 188 Query: 186 LE--EPNVRVLNYAPGPLDTDM 205 E N+ V APG + + M Sbjct: 189 QEIASRNITVNCIAPGFIKSAM 210 >3RSH-A nrPDB Length = 251 Score = 47.0 bits (110), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 54/202 (26%), Positives = 91/202 (45%), Gaps = 21/202 (10%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV-VRVP 67 V L+TGASRG G+ +A LLA G+ ++ +A ++ + + LG G+ + V P Sbjct: 14 VALVTGASRGIGKAIAELLA---ERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNP 70 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 + EA L+ + + +L+NNAG D + + ++ N Sbjct: 71 ESI--EAVLKAITDEFGGVD--------ILVNNAGITRD---NLLMRMKEEEWSDIMETN 117 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 LTS+ L+ +VL+ ++N+ S+ G A Y A KA + +A E Sbjct: 118 LTSIFRLSKAVLRGMMKKR--QGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSMARE 175 Query: 188 EPN--VRVLNYAPGPLDTDMQQ 207 + V V APG ++TDM + Sbjct: 176 VASRGVTVNTVAPGFIETDMTK 197 >2CFC-A nrPDB Length = 250 Score = 46.2 bits (108), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 53/202 (26%), Positives = 88/202 (43%), Gaps = 14/202 (6%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TGAS G G +A + + L LSA E + A++ V+RV A Sbjct: 4 VAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYADK----VLRVRA 59 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ E + + A E + L+NNAG G+ G + + Q + A+N+ Sbjct: 60 DVADEGDVNAAIAATMEQFGAIDV----LVNNAGITGNSEAGVLHTTPVEQFDKVMAVNV 115 Query: 129 TSMLCLTSSVL-KAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 + +VL G+ +VNI+S+ +L F G + Y K A L + +A++ Sbjct: 116 RGIFLGCRAVLPHMLLQGAGV---IVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVD 172 Query: 188 EP--NVRVLNYAPGPLDTDMQQ 207 +R PG ++T M Q Sbjct: 173 YAGSGIRCNAVCPGMIETPMTQ 194 >2UVD-A nrPDB Length = 246 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 59/205 (28%), Positives = 93/205 (45%), Gaps = 15/205 (7%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGASRG GR +A LA +V+V A N++ ++ E+ ++ G + V A Sbjct: 6 VALVTGASRGIGRAIAIDLAK--QGANVVVNYAGNEQKANEVVDEI--KKLGSDAIAVRA 61 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ A + + +++ G Q +L+NNAG D + + + NL Sbjct: 62 DV---ANAEDVTNMVKQTVDVFG-QVDILVNNAGVTKD---NLLMRMKEEEWDTVINTNL 114 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 + T +V + F R +VNI+S+ + G A Y A KA L + A E Sbjct: 115 KGVFLCTKAVSR-FMMRQRHGR-IVNIASVVGVTGNPGQANYVAAKAGVIGLTKTSAKEL 172 Query: 188 -EPNVRVLNYAPGPLDTDMQQLARE 211 N+ V APG + TDM + E Sbjct: 173 ASRNITVNAIAPGFIATDMTDVLDE 197 >6CI9-A nrPDB Length = 259 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/178 (26%), Positives = 79/178 (44%), Gaps = 13/178 (7%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 ++TG S+G GR +A A+ G +V++ RN + L + A+L R + VR AD Sbjct: 12 AIVTGGSKGIGRGIAETFAN---AGVDVVITGRNQDDLDRTVADLSGTRGKVTAVR--AD 66 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + ++ + + R GL ++ NAG S DL+ + +N Sbjct: 67 VTDPEDARRTVA--ETVSRHGGLD--IVCANAGIF--PSGRLEDLTPD-DIEQVLGVNFK 119 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 + + + L+A S G R VV S + + GW+ Y A KAA+ + A+E Sbjct: 120 GTVYIVQAALQALTAS-GHGRVVVTSSITGPITGYPGWSHYGASKAAQLGFLRTAAME 176 >5IZ4-A nrPDB Length = 271 Score = 44.7 bits (104), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 53/200 (26%), Positives = 88/200 (44%), Gaps = 15/200 (7%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGA--ERSGLRVVRV 66 VC++TG++ G G A A + SV + D++ R + + A +G + + Sbjct: 16 VCVITGSASGIGAATALRFAQ--AGWSVAI--GNFDDSTRDAASTVEALCRDAGAQTLIF 71 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 AD+G +A + + + QR+ LIN AG+ + D D + + Sbjct: 72 DADVGKDADCRHAVDMV-----ASRWQRIDALINCAGTTRVIPHNAFDQIDDFEFERVYR 126 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRT--VVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NL + +T + + +S R+ VVN+SSL L Y A K A + L Sbjct: 127 VNLIGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLS 186 Query: 184 LALE-EPNVRVLNYAPGPLD 202 LA P++RV APG +D Sbjct: 187 LARNLAPHIRVNALAPGMVD 206 >3O4R-A nrPDB Length = 261 Score = 44.3 bits (103), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 57/210 (27%), Positives = 96/210 (45%), Gaps = 23/210 (10%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+T ++ G G +A LA G+ +V+S+R + + Q A L E GL V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQ---DGAHVVVSSRKQQNVDQAVATLQGE--GLSVT 67 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 +G ++L+ +L G+ +L++NA V+ F + D T+ W Sbjct: 68 GTVCHVGKAEDRERLVATAVKLH--GGID--ILVSNAA----VNPFFGSIMDVTE--EVW 117 Query: 125 A----LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +N+ + +T +V+ G +VV +SS+ A P G++ Y K A L Sbjct: 118 DKTLDINVKAPALMTKAVVPEMEKRGG--GSVVIVSSIAAFSPSPGFSPYNVSKTALLGL 175 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQL 208 + LA+E N+RV APG + T ++ Sbjct: 176 TKTLAIELAPRNIRVNCLAPGLIKTSFSRM 205 >2ZAT-A nrPDB Length = 260 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 56/206 (27%), Positives = 96/206 (46%), Gaps = 23/206 (11%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+T ++ G G +A LA G+ +V+S+R E + + A L E GL V Sbjct: 16 VALVTASTDGIGLAIARRLAQ---DGAHVVVSSRKQENVDRTVATLQGE--GLSVTGTVC 70 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW---- 124 +G ++L+ L G+ +L++NA V+ F ++ D+T+ W Sbjct: 71 HVGKAEDRERLVAMAVNLH--GGVD--ILVSNAA----VNPFFGNIIDATE--EVWDKIL 120 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N+ + + +T +V+ G +V+ +SS+ A PF Y K A L + L Sbjct: 121 HVNVKATVLMTKAVVPEMEKRGG--GSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTKNL 178 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQL 208 A+E N+RV APG + T+ Q+ Sbjct: 179 AVELAPRNIRVNCLAPGLIKTNFSQV 204 >3V2G-A nrPDB Length = 271 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 58/201 (28%), Positives = 87/201 (43%), Gaps = 18/201 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 +TG SRG G +A LA L +V + E + + +E+ E++G R V + A Sbjct: 33 TAFVTGGSRGIGAAIAKRLA--LEGAAVALTYVNAAERAQAVVSEI--EQAGGRAVAIRA 88 Query: 69 DLGAEAGLQQLLGALRELPRP-KGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D ++Q A+RE GL +L+N+AG ++D +V A+N Sbjct: 89 DNRDAEAIEQ---AIRETVEALGGLD--ILVNSAGIWHSAPLEETTVADFDEV---MAVN 140 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA-- 185 + S + D R + S+L L P+ G +LY A KAA L + LA Sbjct: 141 FRAPFVAIRSASRHLGDG---GRIITIGSNLAELVPWPGISLYSASKAALAGLTKGLARD 197 Query: 186 LEEPNVRVLNYAPGPLDTDMQ 206 L + V PG DTDM Sbjct: 198 LGPRGITVNIVHPGSTDTDMN 218 >2X9N-A nrPDB Length = 288 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 60/208 (28%), Positives = 85/208 (40%), Gaps = 28/208 (13%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARND-EALRQLEAELGAERSGLRVVRVPAD 69 ++TGA++ GR +A L G +V+ N EA L EL ERS VV AD Sbjct: 27 VVTGAAKRIGRAIA---VKLHQTGYRVVIHYHNSAEAAVSLADELNKERSNTAVV-CQAD 82 Query: 70 LGAE----AGLQQLLGA-LRELPRPKGLQRLLLINNAGSL-------GDVSKGFVDLSDS 117 L A ++++ + R R +L+NNA + GD + Sbjct: 83 LTNSNVLPASCEEIINSCFRAFGRCD-----VLVNNASAFYPTPLVQGDHEDNSNGKTVE 137 Query: 118 TQVNNYWALNLTSMLCLTSSVLK----AFPDSPGLNRTVVNISSLCALQPFKGWALYCAG 173 TQV N + LT S + P+ N ++VN+ QP ++LY G Sbjct: 138 TQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNMG 197 Query: 174 KAARDMLFQVLALE--EPNVRVLNYAPG 199 K A L Q ALE +RV APG Sbjct: 198 KHALVGLTQSAALELAPYGIRVNGVAPG 225 >3F9I-A nrPDB Length = 249 Score = 41.6 bits (96), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 56/212 (26%), Positives = 88/212 (41%), Gaps = 23/212 (10%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TGAS G G +A LL L GS +++S N+E L+ L L + + V +L Sbjct: 18 LITGASSGIGSAIARLLHKL---GSKVIISGSNEEKLKSLGNAL-KDNYTIEV----CNL 69 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 + L+ L +L+ NAG D + D +V +NL + Sbjct: 70 ANKEECSNLISKTSNLD--------ILVCNAGITSDTLAIRMKDQDFDKV---IDINLKA 118 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPN 190 L +K R ++NISS+ + G A YCA KA + + L+ E Sbjct: 119 NFILNREAIKKMIQKR-YGR-IINISSIVGIAGNPGQANYCASKAGLIGMTKSLSYEVAT 176 Query: 191 --VRVLNYAPGPLDTDMQQLARETSVDPDMRK 220 + V APG + +DM E + ++K Sbjct: 177 RGITVNAVAPGFIKSDMTDKLNEKQREAIVQK 208 >3LYL-A nrPDB Length = 247 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 52/203 (25%), Positives = 87/203 (42%), Gaps = 16/203 (7%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+TGASRG G +A LA S G+ +V +A + + + E + + G + Sbjct: 3 LNEKVALVTGASRGIGFEVAHALA---SKGATVVGTATSQASAEKFENSM--KEKGFKAR 57 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + ++ +Q + + + L +L+NNAG D + + V N Sbjct: 58 GLVLNISDIESIQNFFAEI----KAENLAIDILVNNAGITRDNLMMRMSEDEWQSVIN-- 111 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NL+S+ ++ ++ R +++I S+ G YCA KA + L Sbjct: 112 -TNLSSIFRMSKECVRGMMKKR-WGR-IISIGSVVGSAGNPGQTNYCAAKAGVIGFSKSL 168 Query: 185 ALE--EPNVRVLNYAPGPLDTDM 205 A E N+ V APG + TDM Sbjct: 169 AYEVASRNITVNVVAPGFIATDM 191 >3DWF-A nrPDB Length = 276 Score = 41.6 bits (96), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 57/208 (27%), Positives = 92/208 (44%), Gaps = 36/208 (17%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEA---ELGAERS-----GL 61 ++TGAS+G GR +A LA + G+ +V++AR+ EAL+++ A ELGA + + Sbjct: 14 VIVTGASKGIGREIAYHLAKM---GAHVVVTARSKEALQKVVARCLELGAASAHYIAGSM 70 Query: 62 RVVRVPADLGAEAGLQQLLGALRELPRPKGL-QRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + + AEAG L+G L L L RL + G + +V K Sbjct: 71 EDMTFAEEFVAEAG--NLMGGLDMLILNHVLYNRLTFFH--GEIDNVRKSM--------- 117 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +N S + L+ + + S G ++ +SS+ + A Y A K A D Sbjct: 118 ----EVNFHSFVVLSVAAMPMLMQSQG---SIAVVSSVAGKITYPLIAPYSASKFALDGF 170 Query: 181 FQVLALE----EPNVRVLNYAPGPLDTD 204 F L E + NV + G +DT+ Sbjct: 171 FSTLRSEFLVNKVNVSITLCILGLIDTE 198 >1K2W-A nrPDB Length = 256 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 51/195 (26%), Positives = 95/195 (48%), Gaps = 18/195 (9%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG++RG GR A + + G+ + ++ N EA R AE+G + + D Sbjct: 8 ALITGSARGIGRAFAE---AYVREGARVAIADINLEAARATAAEIGPAACAIAL-----D 59 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + +A + + + L L R + +L+NNA +L D++ V+++ + + +A+N++ Sbjct: 60 VTDQASIDRCVAEL--LDRWGSID--ILVNNA-ALFDLAP-IVEITRESY-DRLFAINVS 112 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV--LALE 187 L + +V +A + G ++N++S + +YCA KAA L Q L L Sbjct: 113 GTLFMMQAVARAMI-AGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSAGLNLI 171 Query: 188 EPNVRVLNYAPGPLD 202 + V APG +D Sbjct: 172 RHGINVNAIAPGVVD 186 >3FTP-A nrPDB Length = 270 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 105/233 (45%), Gaps = 43/233 (18%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M+ L + V ++TGASRG GR +A LA G++++ +A + + A +++G Sbjct: 22 MDKTLDKQVAIVTGASRGIGRAIALELA---RRGAMVIGTATTEAGAEGIGAAF--KQAG 76 Query: 61 LR----VVRVPADLGAEAGLQQLL---GALRELPRPKGLQRLLLINNAGSLGDVSKGFVD 113 L V+ V +A ++ L GAL +L+NNAG D Sbjct: 77 LEGRGAVLNVNDATAVDALVESTLKEFGALN-----------VLVNNAGITQD------Q 119 Query: 114 LSDSTQVNNYWAL---NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALY 170 L+ + + + A+ NL ++ L+ +VL+ + G +VNI+S+ G Y Sbjct: 120 LAMRMKDDEWDAVIDTNLKAVFRLSRAVLRPMMKARG--GRIVNITSVVGSAGNPGQVNY 177 Query: 171 CAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDM-------QQLARETSV 214 A KA + + LA E + V APG +DTDM QQ A +T + Sbjct: 178 AAAKAGVAGMTRALAREIGSRGITVNCVAPGFIDTDMTKGLPQEQQTALKTQI 230 >2CDH-G nrPDB Length = 244 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/199 (26%), Positives = 87/199 (43%), Gaps = 15/199 (7%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TGASRG G+ +A L + VLV AR+ +A ++ ++ E G + + Sbjct: 3 VVVVTGASRGIGKAIALSLGK--AGCKVLVNYARSAKAAEEVSKQI--EAYGGQAITFGG 58 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ EA ++ + ++ G +++NNAG D + +Q + LNL Sbjct: 59 DVSKEADVEAM---MKTAIDAWGTID-VVVNNAGITRDT---LLIRMKKSQWDEVIDLNL 111 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 T + T + K ++NI+S+ L G A Y A KA + A E Sbjct: 112 TGVFLCTQAATKIMMKKR--KGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREG 169 Query: 188 -EPNVRVLNYAPGPLDTDM 205 N+ V PG + +DM Sbjct: 170 ASRNINVNVVCPGFIASDM 188 >4MOW-A nrPDB Length = 256 Score = 40.8 bits (94), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 57/208 (27%), Positives = 94/208 (45%), Gaps = 27/208 (12%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGA-ERSGLRVVRVP 67 V ++TGAS+G G +A LA G+ +V++ + +A +A + A +G R V V Sbjct: 16 VAIVTGASKGIGAAIAKALA---DEGAAVVVNYASSKA--GADAVVSAITEAGGRAVAVG 70 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNY--- 123 D+ A Q+++ E RL +L+NN+G F + T+ +Y Sbjct: 71 GDVSKAADAQRIVDTAIET-----YGRLDVLVNNSGVY-----EFAPIEAITE-EHYRRQ 119 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 + N+ +L T + +K G +++NISS+ A+Y K A D + V Sbjct: 120 FDTNVFGVLLTTQAAVKHL----GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGV 175 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLA 209 LALE +RV PG + T+ A Sbjct: 176 LALELGPRKIRVNAINPGMIVTEGTHSA 203 >1AE1-A nrPDB Length = 273 Score = 40.4 bits (93), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 53/201 (26%), Positives = 90/201 (44%), Gaps = 15/201 (7%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG S+G G + LA L G+ + +RN++ L + E+ E+ GL V DL Sbjct: 25 LVTGGSKGIGYAIVEELAGL---GARVYTCSRNEKELDEC-LEIWREK-GLNVEGSVCDL 79 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 + +L+ + + K +L+NNAG + + K D ++ N N + Sbjct: 80 LSRTERDKLMQTVAHVFDGK---LNILVNNAGVV--IHKEAKDFTEK-DYNIIMGTNFEA 133 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--E 188 L+ S N V+ +SS+ +LY A K A + + + LA E + Sbjct: 134 AYHLSQIAYPLLKASQ--NGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKSLACEWAK 191 Query: 189 PNVRVLNYAPGPLDTDMQQLA 209 N+RV + APG + T + + A Sbjct: 192 DNIRVNSVAPGVILTPLVETA 212 >4RZH-A nrPDB Length = 247 Score = 40.0 bits (92), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 61/202 (30%), Positives = 92/202 (45%), Gaps = 17/202 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGASRG G+ A LA + V+V A++ A + AE+ A +G + V A Sbjct: 8 VALVTGASRGIGKATA--LALAATGMKVVVNYAQSSTAADAVVAEIIA--NGGEAIAVQA 63 Query: 69 DLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 ++ + QL+ L + R +L+NNAG D + L D V + LN Sbjct: 64 NVANADEVDQLIKTTLDKFSRID-----VLVNNAGITRDTLLLRMKLEDWQAVID---LN 115 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA-- 185 LT + T +V K + ++NI+S+ + G A Y A KA + +A Sbjct: 116 LTGVFLCTKAVSKLMLKQK--SGRIINITSVAGMMGNPGQANYSAAKAGVIGFTKTVAKE 173 Query: 186 LEEPNVRVLNYAPGPLDTDMQQ 207 L V V APG + TDM + Sbjct: 174 LASRGVTVNAVAPGFIATDMTE 195 >1SNY-A nrPDB Length = 267 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 56/207 (27%), Positives = 96/207 (46%), Gaps = 17/207 (8%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG +RG G L L +L P L + RN E ++LE +L S + ++ + DL Sbjct: 25 LITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELE-DLAKNHSNIHILEI--DL 81 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFV----DLSDSTQVNNYWAL 126 +L+ + + + +GL +L NNAG ++ +L D+ Q N + Sbjct: 82 RNFDAYDKLVADIEGVTKDQGLN--VLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPI 139 Query: 127 NLT-SMLCLTSSVLKAFPDSP-GLNR-TVVNISS-LCALQPFK--GWALYCAGKAARDML 180 L + L L KA P G+ R ++N+SS L ++Q G Y K+A + Sbjct: 140 MLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAA 199 Query: 181 FQVLALEEPNVRVL--NYAPGPLDTDM 205 + L+++ R++ + PG + TDM Sbjct: 200 TKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >3U5T-A nrPDB Length = 267 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 52/201 (25%), Positives = 94/201 (46%), Gaps = 21/201 (10%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TGASRG G +A LAS +V++ A A ++ ++ E +G + + A Sbjct: 29 VAIVTGASRGIGAAIAARLAS--DGFTVVINYAGKAAAAEEVAGKI--EAAGGKALTAQA 84 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ A +++L E G+ +L+NNAG + + + D+ + A+NL Sbjct: 85 DVSDPAAVRRLFATAEEA--FGGVD--VLVNNAGIMPLTT--IAETGDAV-FDRVIAVNL 137 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISS--LCALQPFKGWALYCAGKAARDMLFQVLA- 185 T + L+ + ++N+S+ + L P + +Y A KA + + VL+ Sbjct: 138 KG----TFNTLREAAQRLRVGGRIINMSTSQVGLLHP--SYGIYAAAKAGVEAMTHVLSK 191 Query: 186 -LEEPNVRVLNYAPGPLDTDM 205 L ++ V APGP TD+ Sbjct: 192 ELRGRDITVNAVAPGPTATDL 212 >3WTC-A nrPDB Length = 262 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 50/203 (24%), Positives = 90/203 (44%), Gaps = 23/203 (11%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND---EALRQLEAELGAERSGLRVVR 65 + +TGA++G G+ +A LA V++L + D E +++EA G R V Sbjct: 10 IAAVTGAAQGIGKAIALRLAK--DGADVILLDVKQDTLAETAKEVEA------LGRRAVA 61 Query: 66 VPADLGAEAGLQQLLGALRELPRP-KGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + AD+ + Q L + + GL +++NNAG K +D+ + ++ + Sbjct: 62 LTADI---SNRDQFRSTLADAAKTLGGLD--IMVNNAGIC--QVKPILDI-EPAEIEKIF 113 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 ++N+ +L + F + G ++N S+ + + Y A K A L Q Sbjct: 114 SINVQGVLWGMQAAATLFKE-KGTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQSA 172 Query: 185 A--LEEPNVRVLNYAPGPLDTDM 205 A L + V +Y PG + TDM Sbjct: 173 AKELASSGITVNSYCPGIVGTDM 195 >4HBG-A nrPDB Length = 286 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 61/245 (24%), Positives = 99/245 (40%), Gaps = 58/245 (23%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TGA+RG G+ + L G ++ E++ + + G +SGL R A Sbjct: 6 VAIVTGATRGIGKAIC---QKLFQKGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 Query: 69 ------------DLGAEAGLQQLLGALRELPRPKGLQRL--------------------L 96 D + G++ RP Q+ L Sbjct: 63 IAIDFKKWPHWLDYESYDGIEYFKD------RPPLKQKYSTLFDPCNKWSNNERRYYVNL 116 Query: 97 LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKA-------FPDSPGLN 149 LIN AG + + ++Q+ + +N S + +T+ +K +P+ G + Sbjct: 117 LINCAGL---TQESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQS 173 Query: 150 R--TVVNISSLCALQPFK--GWALYCAGKAARDMLFQVLALE-EP-NVRVLNYAPGPLD- 202 T+VNISS+ K G ++Y A KAA +VLA E EP N+R +PG + Sbjct: 174 ARPTIVNISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKG 233 Query: 203 TDMQQ 207 TDM Q Sbjct: 234 TDMIQ 238 >3OEC-A nrPDB Length = 317 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 60/209 (28%), Positives = 89/209 (42%), Gaps = 23/209 (11%) Query: 9 VCLLTGASRGFGRTLAPLLAS---------LLSPGSVLVLSARNDEALRQLEAELGAERS 59 V +TGA+RG GRT A LA L L + + E L+ E E Sbjct: 48 VAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELK--ETVRLVEEQ 105 Query: 60 GLRVVRVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST 118 G R++ AD+ A LQ ++ AL E L + I+N G + V L+D Sbjct: 106 GRRIIARQADVRDLASLQAVVDEALAEFGHIDILVSNVGISNQGEV-------VSLTDQ- 157 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 Q ++ NL +VL + + G +V+ +SS L+ G + Y A K Sbjct: 158 QWSDILQTNLIGAWHACRAVLPSMIER-GQGGSVIFVSSTVGLRGAPGQSHYAASKHGVQ 216 Query: 179 MLFQVLALE--EPNVRVLNYAPGPLDTDM 205 L LA E N+RV + PG ++T+M Sbjct: 217 GLMLSLANEVGRHNIRVNSVNPGAVNTEM 245 >4E6P-A nrPDB Length = 259 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 48/195 (24%), Positives = 91/195 (46%), Gaps = 18/195 (9%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG++RG GR A + + G+ + ++ + E RQ AE+G +++ D Sbjct: 11 ALITGSARGIGRAFAE---AYVREGATVAIADIDIERARQAAAEIGPAAYAVQM-----D 62 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + + + + A E GL +L+NNA +L D++ V+++ + +A+N+ Sbjct: 63 VTRQDSIDAAIAATVE--HAGGLD--ILVNNA-ALFDLAP-IVEITRES-YEKLFAINVA 115 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 L + + + G ++N++S + A+YCA KAA L Q L+ Sbjct: 116 GTLFTLQAAARQMI-AQGRGGKIINMASQAGRRGEALVAIYCATKAAVISLTQSAGLDLI 174 Query: 188 EPNVRVLNYAPGPLD 202 + + V APG +D Sbjct: 175 KHRINVNAIAPGVVD 189 >5PGZ-A nrPDB Length = 276 Score = 38.1 bits (87), Expect = 0.003, Method: Compositional matrix adjust. Identities = 55/207 (26%), Positives = 92/207 (44%), Gaps = 34/207 (16%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEA---ELGAERSG-----L 61 ++TGAS+G GR +A L+ + G+ +VL+AR++E L+++ + ELGA + + Sbjct: 21 VIVTGASKGIGREMAYHLSKM---GAHVVLTARSEEGLQKVVSRCLELGAASAHYIAGTM 77 Query: 62 RVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVN 121 + +AG +L+G L +LI N + +S F D D V Sbjct: 78 EDMTFAEQFIVKAG--KLMGGLD-----------MLILNHITQTSLSL-FHD--DIHSVR 121 Query: 122 NYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLF 181 +N S + ++++ L S G ++ ISSL A Y A K A D F Sbjct: 122 RVMEVNFLSYVVMSTAALPMLKQSNG---SIAVISSLAGKMTQPMIAPYSASKFALDGFF 178 Query: 182 QVLALE----EPNVRVLNYAPGPLDTD 204 + E + NV + G +DT+ Sbjct: 179 STIRTELYITKVNVSITLCVLGLIDTE 205 >4DRY-A nrPDB Length = 281 Score = 37.0 bits (84), Expect = 0.008, Method: Compositional matrix adjust. Identities = 52/183 (28%), Positives = 76/183 (41%), Gaps = 17/183 (9%) Query: 29 SLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPR 88 +L + G +V++ R + L E+G R+G V V D+G + L A+R Sbjct: 52 ALSAEGYSVVITGRRPDVLDAAAGEIGG-RTGNIVRAVVCDVGDPDQVAALFAAVR---- 106 Query: 89 PKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPG 147 RL LL+NNAGS +V ++ Q N A NLT T + Sbjct: 107 -AEFARLDLLVNNAGS--NVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTP 163 Query: 148 LNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLD----- 202 ++N S+ A P A Y A K A L + AL+ R+ + A G +D Sbjct: 164 RGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDG---RMHDIACGQIDIGNAA 220 Query: 203 TDM 205 TDM Sbjct: 221 TDM 223 >1GEG-A nrPDB Length = 256 Score = 35.8 bits (81), Expect = 0.018, Method: Compositional matrix adjust. Identities = 47/210 (22%), Positives = 91/210 (43%), Gaps = 16/210 (7%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + V L+TGA +G G+ +A L+ G + ++ ND + + +E+ ++G V V Sbjct: 2 KKVALVTGAGQGIGKAIA---LRLVKDGFAVAIADYNDATAKAVASEI--NQAGGHAVAV 56 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ + Q+ A+ + + G +++NNAG ++ V+ + + Sbjct: 57 KVDV---SDRDQVFAAVEQARKTLG-GFDVIVNNAGVAPSTP---IESITPEIVDKVYNI 109 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA- 185 N+ ++ + ++AF G ++N S A+Y + K A L Q A Sbjct: 110 NVKGVIWGIQAAVEAFKKE-GHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR 168 Query: 186 -LEEPNVRVLNYAPGPLDTDM-QQLARETS 213 L + V Y PG + T M ++ R+ S Sbjct: 169 DLAPLGITVNGYCPGIVKTPMWAEIDRQVS 198 >1AHH-A nrPDB Length = 255 Score = 35.8 bits (81), Expect = 0.022, Method: Compositional matrix adjust. Identities = 56/213 (26%), Positives = 100/213 (46%), Gaps = 23/213 (10%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 ++TGA G G+ +A A+ G+ +V+S N +A + E+ ++ G + D+ Sbjct: 15 IITGAGAGIGKEIAITFAT---AGASVVVSDINADAANHVVDEI--QQLGGQAFACRCDI 69 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGF-VDLSDSTQVNNYWALNLT 129 +E Q L AL + K + +L+NNAG G K F + ++D + + LN+ Sbjct: 70 TSE----QELSALADFAISKLGKVDILVNNAGGGG--PKPFDMPMADFRRA---YELNVF 120 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 S L+ V + G ++ I+S+ A Y + KAA L + +A + Sbjct: 121 SFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAAASHLVRNMAFDLG 178 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRK 220 E N+RV APG + TD A ++ + P++ + Sbjct: 179 EKNIRVNGIAPGAILTD----ALKSVITPEIEQ 207 >4JRO-A nrPDB Length = 271 Score = 35.4 bits (80), Expect = 0.024, Method: Compositional matrix adjust. Identities = 54/204 (26%), Positives = 85/204 (41%), Gaps = 25/204 (12%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND----EALRQLEAELGAERSGLRV- 63 V ++TG SRG GR +A LA G+ + + E +L AE G E ++ Sbjct: 31 VAVVTGGSRGIGRDIAINLA---KEGANIFFNYNGSPEAAEETAKLVAEHGVEVEAMKAN 87 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V + D+ +A +Q A+ R +L+NNAG D + + ++ Sbjct: 88 VAIAEDV--DAFFKQ---AIERFGRVD-----ILVNNAGITRD---NLLMRMKEDEWDDV 134 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NL T +V + ++N++S+ L G A Y A KA L + Sbjct: 135 ININLKGTFLCTKAVSRTMMKQRA--GKIINMASVVGLIGNAGQANYVASKAGVIGLTKT 192 Query: 184 LALE-EP-NVRVLNYAPGPLDTDM 205 A E P + V APG + TDM Sbjct: 193 TARELAPRGINVNAVAPGFITTDM 216 >5OJG-A nrPDB Length = 260 Score = 35.4 bits (80), Expect = 0.025, Method: Compositional matrix adjust. Identities = 51/210 (24%), Positives = 93/210 (44%), Gaps = 30/210 (14%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARN----DEALRQLEAELGAERSGL-RV 63 V ++T A++G G +A LL G+ +V+ +RN DEA+ L+ GL +V Sbjct: 12 VAIVTAATKGIGLAIAE---RLLDEGASVVIGSRNQKNVDEAIEYLK------NKGLTKV 62 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAG---SLGDVSKGFVDLSDSTQV 120 + + + ++L+ + K + +L+NN G + G + +++SD Sbjct: 63 AGIAGHIASTDDQKKLV----DFTLQKFGKINILVNNHGINPAFGHI----LEVSDQVW- 113 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + + +N+ + +T V G ++ +S A + G A Y K L Sbjct: 114 DKLFEVNVKAGFQMTKLVHPHIAKEGG--GAIIFNASYSAYKSPPGIAAYGVTKTTLVGL 171 Query: 181 FQVLA--LEEPNVRVLNYAPGPLDTDMQQL 208 + LA L + N+RV APG + T M Q+ Sbjct: 172 TRALAMGLAKDNIRVNGIAPGVIKTKMSQV 201 >2HQ1-A nrPDB Length = 247 Score = 35.0 bits (79), Expect = 0.029, Method: Compositional matrix adjust. Identities = 57/215 (26%), Positives = 90/215 (41%), Gaps = 25/215 (11%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSAR-NDEALRQLEAELGAERSGLRVVRVPA 68 ++TG+SRG G+ +A L ++ G+ +VL+ +L E A +G+ VV Sbjct: 8 AIVTGSSRGLGKAIAWKLGNM---GANIVLNGSPASTSLDATAEEFKA--AGINVVVAKG 62 Query: 69 DLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ ++ ++ A+ R +L+NNAG D + D V N N Sbjct: 63 DVKNPEDVENMVKTAMDAFGRID-----ILVNNAGITRDTLMLKMSEKDWDDVLN---TN 114 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 L S T +V K + ++NI+S+ + G A Y A KA + +A E Sbjct: 115 LKSAYLCTKAVSKIMLKQK--SGKIINITSIAGIIGNAGQANYAASKAGLIGFTKSIAKE 172 Query: 188 --EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRK 220 + APG + TDM T V PD K Sbjct: 173 FAAKGIYCNAVAPGIIKTDM------TDVLPDKVK 201 >3E9N-A nrPDB Length = 245 Score = 34.7 bits (78), Expect = 0.042, Method: Compositional matrix adjust. Identities = 51/206 (24%), Positives = 84/206 (40%), Gaps = 26/206 (12%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L + + ++TGA+ G G + LS ++ RN E L L G E +V Sbjct: 3 LKKKIAVVTGATGGMGIEIV----KDLSRDHIVYALGRNPEHLAALAEIEGVEPIESDIV 58 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + ++ E G+ +L K L + L++ A D + ++ + + + Sbjct: 59 K---EVLEEGGVDKL----------KNLDHVDTLVHAAAVARDTT---IEAGSVAEWHAH 102 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 LN+ L+ +L A + G V+ I+S P G +Y A K A L Sbjct: 103 LDLNVIVPAELSRQLLPALRAASGC---VIYINSGAGNGPHPGNTIYAASKHALRGLADA 159 Query: 184 LALEEPN--VRVLNYAPGPLDTDMQQ 207 EE N +RV +PGP +T M Q Sbjct: 160 FRKEEANNGIRVSTVSPGPTNTPMLQ 185 >4K6F-A nrPDB Length = 255 Score = 33.9 bits (76), Expect = 0.069, Method: Compositional matrix adjust. Identities = 53/203 (26%), Positives = 85/203 (41%), Gaps = 15/203 (7%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 + + + ++TG G G ++ L + V+V + N+ + E+ A +G Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLND--AGHRVVVTYSPNNTGADRWLTEMHA--AGREFH 64 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 P D+ QQ + ++ R G +L +NNAG D++ +D + V Sbjct: 65 AYPVDVADHDSCQQ---CIEKIVRDVGPVDIL-VNNAGITRDMTLRKLDKVNWDAVIR-- 118 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NL S+ +T V + G R +VNISS+ + G Y A KA + L Sbjct: 119 -TNLDSVFNMTKPVCDGMVER-GWGR-IVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSL 175 Query: 185 ALE--EPNVRVLNYAPGPLDTDM 205 ALE V V +PG L T M Sbjct: 176 ALEIARKGVTVNTVSPGYLATKM 198 >2FWM-X nrPDB Length = 250 Score = 33.9 bits (76), Expect = 0.074, Method: Compositional matrix adjust. Identities = 38/125 (30%), Positives = 50/125 (40%), Gaps = 15/125 (12%) Query: 93 QRLL--------LINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPD 144 QRLL L+N AG L G D +A+N+ L + F Sbjct: 66 QRLLAETERLDALVNAAGIL---RMGATDQLSKEDWQQTFAVNVGGAFNLFQQTMNQFRR 122 Query: 145 SPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLD 202 G +V ++S A P G + Y A KAA L + LE VR +PG D Sbjct: 123 QRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSLALSVGLELAGSGVRCNVVSPGSTD 180 Query: 203 TDMQQ 207 TDMQ+ Sbjct: 181 TDMQR 185 >3WYE-A nrPDB Length = 256 Score = 33.5 bits (75), Expect = 0.086, Method: Compositional matrix adjust. Identities = 51/210 (24%), Positives = 101/210 (48%), Gaps = 16/210 (7%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + V L+TGA +G G+ +A L+ G + ++ ND + + +E+ ++G V V Sbjct: 2 KKVALVTGAGQGIGKAIA---LRLVKDGFAVAIADYNDATAKAVASEI--NQAGGHAVAV 56 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ + Q+ A+ + + G +++NNAG + + K +++++ + +++ Sbjct: 57 KVDV---SDRDQVFAAVEQARKTLG-GFDVIVNNAG-IAQI-KPLLEVTEE-DLKQIYSV 109 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA- 185 N+ S+ + ++AF G ++N +S+ A+Q F + Y K A L Q A Sbjct: 110 NVFSVFFGIQAAVEAFKKE-GHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAAR 168 Query: 186 -LEEPNVRVLNYAPGPLDTDM-QQLARETS 213 L + V Y PG + T M +Q+ E S Sbjct: 169 DLAPLGITVNGYCPGIVGTGMWEQIDAELS 198 >5YSS-A nrPDB Length = 256 Score = 33.5 bits (75), Expect = 0.086, Method: Compositional matrix adjust. Identities = 57/242 (23%), Positives = 104/242 (42%), Gaps = 32/242 (13%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND-EALRQLEAELGAERSGLRVVRVP 67 L+TG++ G G +A +LA G+ L+L+ D +A + A+ G + P Sbjct: 7 TALVTGSTSGIGLGIAQVLAQ---AGATLILNGFGDVDAAKDAVAQYG---------KTP 54 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 GA+ + + + + +LINNAG + VS ++ + N A+N Sbjct: 55 GYHGADLSDEAQIADMMRYAESEFGGVDILINNAG-IQHVSP--IETFPVDKWNAIIAIN 111 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRT----VVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 L+S+ T L PG+ ++NI+S+ L K + Y A K L + Sbjct: 112 LSSVFHTTRLAL------PGMRARNWGRIINIASVHGLVASKEKSAYVAAKHGVVGLTKT 165 Query: 184 LALEEPNVRVLNYA--PGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 +ALE + A PG + T + Q +D + +G + A+ L+ K +++ Sbjct: 166 IALETAQTEITCNALCPGWVLTPLVQ----QQIDKRIAEGAEPEAARDALLAEKQPSREF 221 Query: 242 LS 243 ++ Sbjct: 222 VT 223 >5TQV-A nrPDB Length = 233 Score = 33.5 bits (75), Expect = 0.10, Method: Compositional matrix adjust. Identities = 50/197 (25%), Positives = 87/197 (44%), Gaps = 20/197 (10%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+ GASRG GR + G ++ +AR+D +L L A LGA L + + P Sbjct: 12 VLIVGASRGLGR---EFVRQYQRDGWNVIATARDDASLAALRA-LGAHAHALDITQ-PEQ 66 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + A LG + G + + + +G G ++G V+ S + N+ Sbjct: 67 IAA-------LGW-----KLDGERLDVAVVVSGVYGPRTEG-VETIASDDFDTVMHTNVR 113 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVN-ISSLCALQPFKGWALYCAGKAARDMLFQVLALEE 188 + L +L D+ G+ V + + S+ GW LY A KAA + + ++ +L+ Sbjct: 114 GPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLRIASLQT 172 Query: 189 PNVRVLNYAPGPLDTDM 205 + ++ PG + TDM Sbjct: 173 RHAACISLHPGWVRTDM 189 >5ILO-A nrPDB Length = 271 Score = 33.1 bits (74), Expect = 0.12, Method: Compositional matrix adjust. Identities = 36/135 (26%), Positives = 59/135 (43%), Gaps = 10/135 (7%) Query: 128 LTSMLCLTSSVLKAFP----DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 L ++ + +S L A P D+ G VVN+SS+ L P +Y A KA + Sbjct: 114 LVNLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRC 173 Query: 184 LALEE----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQ 239 LA E+ ++ + PG TDM E + P+ + + ++ Sbjct: 174 LANEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNKQSAADVSR 233 Query: 240 KLLSLLEKDEFKSGA 254 +L++LEKD K+GA Sbjct: 234 CILNVLEKD--KNGA 246 >4IS3-A nrPDB Length = 268 Score = 33.1 bits (74), Expect = 0.13, Method: Compositional matrix adjust. Identities = 50/201 (24%), Positives = 85/201 (42%), Gaps = 18/201 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARN-DEALRQLEAELGAERSGLRVVRVP 67 V ++TG +RG G A + + S+ + D AL QL+ EL E V+ Sbjct: 27 VTIITGGTRGIGFAAAKIFIDNGAKVSIFGETQEEVDTALAQLK-ELYPEE---EVLGFA 82 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 DL + ++ A+ ++ + G RL ++INNAG S + + + Sbjct: 83 PDLTSR---DAVMAAVGQVAQKYG--RLDVMINNAGI---TSNNVFSRVSEEEFKHIMDI 134 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 N+T + + D+ ++N +S+ + Y A KA+ L L Sbjct: 135 NVTGVFNGAWCAYQCMKDAK--KGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGLGR 192 Query: 187 E--EPNVRVLNYAPGPLDTDM 205 E N+RV+ APG ++TDM Sbjct: 193 EIIRKNIRVVGVAPGVVNTDM 213 >6NRP-A nrPDB Length = 263 Score = 32.7 bits (73), Expect = 0.15, Method: Compositional matrix adjust. Identities = 56/205 (27%), Positives = 92/205 (44%), Gaps = 28/205 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS---GLRVVRV 66 L+TG+SRG G+ +A LA G + + AR+ RQ EAE + G + Sbjct: 27 ILVTGSSRGIGKAIALQLA---KAGFDVTVHARS----RQAEAEQVVQEIQALGQNSHYL 79 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ +QQ+L +++ + G ++L NAG D F L+D W Sbjct: 80 MFDVNERQTVQQILE--QDVEQHGGFYGVVL--NAGLTHD--GAFPALTDQD-----WDE 128 Query: 127 NLTSMLCLTSSVLKAFPDSPGLN----RTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +++ L +VLK P ++ +V +SS+ + +G Y A KA + Sbjct: 129 VISTSLDGFYNVLKPLI-MPMIHLRKGGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATK 187 Query: 183 VLALE--EPNVRVLNYAPGPLDTDM 205 LALE + + V APG ++T+M Sbjct: 188 ALALELAKRKITVNCVAPGLIETEM 212 >3RWB-A nrPDB Length = 247 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 47/197 (23%), Positives = 87/197 (44%), Gaps = 18/197 (9%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TGA++G G+ +A A L + G+ +++S N E + A +G + + AD Sbjct: 9 ALVTGAAQGIGKAIA---ARLAADGATVIVSDINAEGAKAAAASIGKKARA-----IAAD 60 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + ++ L ++ L G+ +L+NNA + V+ VDL ++ + +NLT Sbjct: 61 ISDPGSVKALFAEIQAL--TGGID--ILVNNASIVPFVAWDDVDLDHWRKIID---VNLT 113 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 +T + + R V++I+S A Y A K + LA E Sbjct: 114 GTFIVTRAGTDQMRAAGKAGR-VISIASNTFFAGTPNMAAYVAAKGGVIGFTRALATELG 172 Query: 188 EPNVRVLNYAPGPLDTD 204 + N+ PG +++D Sbjct: 173 KYNITANAVTPGLIESD 189 >1O5I-A nrPDB Length = 249 Score = 32.7 bits (73), Expect = 0.16, Method: Compositional matrix adjust. Identities = 52/206 (25%), Positives = 85/206 (41%), Gaps = 31/206 (15%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 ME G+ L+ ASRG GR +A +L+ G+ + + ARN+E L+ RSG Sbjct: 13 MELGIRDKGVLVLAASRGIGRAVADVLS---QEGAEVTICARNEELLK---------RSG 60 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 R V DL + L L ++E+ +L+ NAG GF D + Sbjct: 61 HRY--VVCDLRKD--LDLLFEKVKEVD--------ILVLNAGG---PKAGFFDELTNEDF 105 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +M+ + + L A + G R +V I+S + P + + + A Sbjct: 106 KEAIDSLFLNMIKIVRNYLPAMKEK-GWGR-IVAITSFSVISPIENLYTSNSARMALTGF 163 Query: 181 FQVLALEEP--NVRVLNYAPGPLDTD 204 + L+ E + V APG +T+ Sbjct: 164 LKTLSFEVAPYGITVNCVAPGWTETE 189 >4M8S-A nrPDB Length = 248 Score = 32.3 bits (72), Expect = 0.22, Method: Compositional matrix adjust. Identities = 58/248 (23%), Positives = 104/248 (41%), Gaps = 30/248 (12%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDE---ALRQLEAELGAERSGLRVVR 65 + L+TGASRG G A + +L + G+ ++ +A ++ A+ + A+ G E L Sbjct: 10 IALVTGASRGIG---AAIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVLNSAE 66 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 A +++ G L +L+NNAG D + + ++ Sbjct: 67 PETVENLIADIEKTFGKLD-----------ILVNNAGITRD---NLLMRMKEEEWDDIMQ 112 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 +NL S+ + +VL+ ++NI+S+ + G Y A KA + +A Sbjct: 113 VNLKSVFRASKAVLRGMMKQRA--GRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSMA 170 Query: 186 LE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 E + V APG +DTDM + ++ + R+ A G+ D + A +L Sbjct: 171 REVGSRGITVNCVAPGFIDTDMTR-----ALPEETRQTFTAQTALGRFGDAQDIADAVL- 224 Query: 244 LLEKDEFK 251 L D+ K Sbjct: 225 FLASDQAK 232 >1E3W-A nrPDB Length = 261 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 50/216 (23%), Positives = 88/216 (40%), Gaps = 27/216 (12%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG + G G + A L + ++L N E E A++ G + PA Sbjct: 12 VAVITGGASGLGLSTAKRLVG--QGATAVLLDVPNSEG------ETEAKKLGGNCIFAPA 63 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVD-------LSDSTQVN 121 ++ +E +Q L +E R+ + N + K + + L D +V Sbjct: 64 NVTSEKEVQAALTLAKE-----KFGRIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVI 118 Query: 122 NYWALNLTSMLCLTSSVL-KAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 N + +++ L + V+ + PD G ++N +S+ A + G A Y A K + Sbjct: 119 NVNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 178 Query: 181 FQVLA--LEEPNVRVLNYAPG----PLDTDMQQLAR 210 +A L +RV+ APG PL T + R Sbjct: 179 TLPIARDLAPIGIRVVTIAPGLFATPLLTTLPDTVR 214 >4CQL-A nrPDB Length = 261 Score = 32.0 bits (71), Expect = 0.27, Method: Compositional matrix adjust. Identities = 37/140 (26%), Positives = 58/140 (41%), Gaps = 9/140 (6%) Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + A+NL +T + +A S G +++NISS+ G Y A KA L Sbjct: 121 DKVIAVNLKGTFLVTQAAAQALV-SNGCRGSIINISSIVGKVGNVGQTNYAASKAGVIGL 179 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 Q A E +R + PG + T M Q + VD + E+ G L D + A Sbjct: 180 TQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVDK-----ITEMIPMGHLGDPEDVA 234 Query: 239 QKLLSLLEKDE-FKSGAHVD 257 + L +D + +G V+ Sbjct: 235 DVVAFLASEDSGYITGTSVE 254 >1DOH-A nrPDB Length = 283 Score = 32.0 bits (71), Expect = 0.29, Method: Compositional matrix adjust. Identities = 46/206 (22%), Positives = 85/206 (41%), Gaps = 17/206 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGA RG GR +A L V+V A + E+ ++ A + +++G V A Sbjct: 31 VALVTGAGRGIGREMAMELGRRGC--KVIVNYANSTESAEEVVAAI--KKNGSDAACVKA 86 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 ++G ++ ++ E + G ++ N+ G VS G V + + + +N Sbjct: 87 NVGV---VEDIVRMFEEAVKIFGKLDIVCSNS----GVVSFGHVKDVTPEEFDRVFTINT 139 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 + K R ++ S + A+Y K A + + +A++ Sbjct: 140 RGQFFVAREAYKHLEIG---GRLILMGSITGQAKAVPKHAVYSGSKGAIETFARCMAIDM 196 Query: 188 -EPNVRVLNYAPGPLDTDMQQ-LARE 211 + + V APG + TDM + RE Sbjct: 197 ADKKITVNVVAPGGIKTDMYHAVCRE 222 >4NBT-A nrPDB Length = 240 Score = 30.8 bits (68), Expect = 0.60, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 30/59 (50%), Gaps = 4/59 (6%) Query: 151 TVVNISSLCALQPFKGWALYCAGKAARDMLFQV----LALEEPNVRVLNYAPGPLDTDM 205 +++NISS+ + G A Y A KA L AL+ NVRV APG + TD+ Sbjct: 127 SIINISSVVGVFGNIGQANYAATKAGVIGLTMTWAKEFALKGANVRVNAIAPGYIMTDI 185 >4DMM-A nrPDB Length = 269 Score = 30.8 bits (68), Expect = 0.67, Method: Compositional matrix adjust. Identities = 62/208 (29%), Positives = 91/208 (43%), Gaps = 20/208 (9%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 + L+TGASRG GR +A LA+ + +V S+ A E +G V A Sbjct: 30 IALVTGASRGIGRAIALELAAAGAKVAVNYASS----AGAADEVVAAIAAAGGEAFAVKA 85 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRL-LLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ E+ ++ L A+ E RL +L+NNAG D + D V + LN Sbjct: 86 DVSQESEVEALFAAVIER-----WGRLDVLVNNAGITRDTLLLRMKRDDWQSVLD---LN 137 Query: 128 LTSM-LCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA- 185 L + LC ++ G ++NI+S+ G A Y A KA L + +A Sbjct: 138 LGGVFLCSRAAAKIMLKQRSG---RIINIASVVGEMGNPGQANYSAAKAGVIGLTKTVAK 194 Query: 186 -LEEPNVRVLNYAPGPLDTDM-QQLARE 211 L + V APG + TDM +LA E Sbjct: 195 ELASRGITVNAVAPGFIATDMTSELAAE 222 >2HRB-A nrPDB Length = 274 Score = 30.4 bits (67), Expect = 0.73, Method: Compositional matrix adjust. Identities = 51/165 (30%), Positives = 71/165 (43%), Gaps = 23/165 (13%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLS--ARNDEALRQLEAELGAERSGLRV 63 G V L+TGA+RG G +A L S VL AR A++QL+AE GL Sbjct: 1 GSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAE------GLS- 53 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSL--GDVSKGFVDLSDSTQVN 121 P + Q + ALR+ R + +L+NNA D F ++ T Sbjct: 54 ---PRFHQLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKT 110 Query: 122 NYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKG 166 N++A T +C + P R VVNISSL L+ F+ Sbjct: 111 NFFA---TRNMC-----NELLPIMKPHGR-VVNISSLQCLRAFEN 146 >5U9P-A nrPDB Length = 265 Score = 30.4 bits (67), Expect = 0.81, Method: Compositional matrix adjust. Identities = 49/199 (24%), Positives = 85/199 (42%), Gaps = 16/199 (8%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG+ RG G TLA LA G+ +V++ RN+E L E G D+ Sbjct: 24 LITGSGRGIGLTLARGLA---EAGAAIVINDRNEEKAATLARRFRDE--GFAADHAVFDV 78 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 A Q+ A+ E G +L+NNAG + +D + + +NL Sbjct: 79 AEHA---QVRAAIDEFEARVGAID-ILVNNAGIQ---RRAPLDAFEPDDWHALMRVNLDG 131 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--E 188 + + +V + + G + ++NI S+ + A Y A K A ML + + + Sbjct: 132 VFNVAQAVARHMI-ARGHGK-IINICSVQSELARPTIAPYAATKGAVRMLTKGMCADWAR 189 Query: 189 PNVRVLNYAPGPLDTDMQQ 207 ++ APG +T++ + Sbjct: 190 YGIQANGLAPGYFETELNR 208 >4GKB-A nrPDB Length = 258 Score = 30.4 bits (67), Expect = 0.84, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 39/79 (49%), Gaps = 4/79 (5%) Query: 152 VVNISSLCALQPFKGWALYCAGKAARDMLFQ--VLALEEPNVRVLNYAPGPLDTDMQQLA 209 +VNISS A+ + YCA K A+ L + +AL E VRV P + T + + Sbjct: 135 IVNISSKTAVTGQGNTSGYCASKGAQLALTREWAVALREHGVRVNAVIPAEVMTPLYRNW 194 Query: 210 RETSVDPDMRKGLQELKAK 228 T DP+ + L E+ AK Sbjct: 195 IATFEDPEAK--LAEIAAK 211 >4AVY-A nrPDB Length = 242 Score = 30.0 bits (66), Expect = 1.1, Method: Compositional matrix adjust. Identities = 56/197 (28%), Positives = 82/197 (41%), Gaps = 29/197 (14%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG S G G +A A L + L L A A R R+ R D+ Sbjct: 15 LVTGGSSGIGAAIAMQFAELGAEVVALGLDADGVHAPRH-----------PRIRREELDI 63 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 LQ+L AL L +L+NNAG D + DL+ +V LNL++ Sbjct: 64 TDSQRLQRLFEALPRLD--------VLVNNAGISRDREE--YDLATFERVLR---LNLSA 110 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--E 188 + L S + + G +++NI+S+ + Y A K A L + LA E Sbjct: 111 AM-LASQLARPLLAQRG--GSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLACEYAA 167 Query: 189 PNVRVLNYAPGPLDTDM 205 +RV APG +DT + Sbjct: 168 ERIRVNAIAPGWIDTPL 184 >3G8Q-A nrPDB Length = 278 Score = 29.6 bits (65), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 25/48 (52%), Gaps = 2/48 (4%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAEL 54 R CLLTG RGF +AP +L ++V DEA+ L+ EL Sbjct: 140 RVYCLLTG--RGFDADIAPAPENLSGRVEIMVTRGDPDEAVELLKEEL 185 >1NFF-A nrPDB Length = 260 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 58/214 (27%), Positives = 93/214 (43%), Gaps = 21/214 (9%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M G L V L++G +RG G A + ++++ G+ +V DE + + AEL Sbjct: 1 MSGRLTGKVALVSGGARGMG---ASHVRAMVAEGAKVVFGDILDEEGKAMAAELADAARY 57 Query: 61 LRV-VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119 + + V PA +A + + A GL +L+NNAG L + G ++ T+ Sbjct: 58 VHLDVTQPAQW--KAAVDTAVTAF------GGLH--VLVNNAGIL---NIGTIEDYALTE 104 Query: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 +NLT + +V+K P +++NISS+ L Y A K A Sbjct: 105 WQRILDVNLTGVFLGIRAVVK--PMKEAGRGSIINISSIEGLAGTVACHGYTATKFAVRG 162 Query: 180 LFQVLALE--EPNVRVLNYAPGPLDTDMQQLARE 211 L + ALE +RV + PG + T M E Sbjct: 163 LTKSTALELGPSGIRVNSIHPGLVKTPMTDWVPE 196 >2O23-A nrPDB Length = 265 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 50/207 (24%), Positives = 79/207 (38%), Gaps = 23/207 (11%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG + G G A L + +L L EA A++ G V PA Sbjct: 14 VAVITGGASGLGLATAERLVGQGASAVLLDLPNSGGEAQ--------AKKLGNNCVFAPA 65 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ +E +Q L L + K R+ + N + SK + T + L Sbjct: 66 DVTSEKDVQTAL----ALAKGK-FGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVL 120 Query: 129 TSMLCLTSSVLKAF--------PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 L T +V++ PD G ++N +S+ A + G A Y A K + Sbjct: 121 DVNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGM 180 Query: 181 FQVLA--LEEPNVRVLNYAPGPLDTDM 205 +A L +RV+ APG T + Sbjct: 181 TLPIARDLAPIGIRVMTIAPGLFGTPL 207 >4FC7-A nrPDB Length = 277 Score = 29.3 bits (64), Expect = 1.8, Method: Compositional matrix adjust. Identities = 39/127 (30%), Positives = 53/127 (41%), Gaps = 33/127 (25%) Query: 140 KAFPDSPGLNRTVVNISSLC-----ALQPFKGWALYCAGKAARDMLFQVLALE--EPNVR 192 K F D G+ +VNI++ ALQ G A KAA D + + LA+E N+R Sbjct: 150 KFFRDHGGV---IVNITATLGNRGQALQVHAGSA-----KAAVDAMTRHLAVEWGPQNIR 201 Query: 193 VLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKS 252 V + APGP+ +GL+ L + KV+A L L K E Sbjct: 202 VNSLAPGPISGT---------------EGLRRLGGPQASLSTKVTASPLQRLGNKTEI-- 244 Query: 253 GAHVDFY 259 AH Y Sbjct: 245 -AHSVLY 250 >3OSU-A nrPDB Length = 246 Score = 29.3 bits (64), Expect = 2.0, Method: Compositional matrix adjust. Identities = 51/199 (25%), Positives = 86/199 (43%), Gaps = 17/199 (8%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TGASRG GR++A LA +V V A + E + E+ A+ G+ + A+ Sbjct: 7 ALVTGASRGIGRSIALQLAE--EGYNVAVNYAGSKEKAEAVVEEIKAK--GVDSFAIQAN 62 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + A ++ ++E+ G +L+NNAG D + + ++ NL Sbjct: 63 V---ADADEVKAMIKEVVSQFG-SLDVLVNNAGITRD---NLLMRMKEQEWDDVIDTNLK 115 Query: 130 SML-CLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 + C+ + + G ++N+SS+ G A Y A KA L + A E Sbjct: 116 GVFNCIQKATPQMLRQRSG---AIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAAREL 172 Query: 188 -EPNVRVLNYAPGPLDTDM 205 + V APG + +DM Sbjct: 173 ASRGITVNAVAPGFIVSDM 191 >2N03-A nrPDB Length = 215 Score = 28.9 bits (63), Expect = 2.1, Method: Compositional matrix adjust. Identities = 27/94 (28%), Positives = 45/94 (47%), Gaps = 14/94 (14%) Query: 150 RTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPG--PLDTDMQQ 207 RT +S+ AL+ KGW Y AG+ ++ + L EP+ PG PLD +Q+ Sbjct: 109 RTKTKMSAAQALK--KGWLYYEAGQRFLEVQYLTGGLIEPDT------PGRVPLDEALQR 160 Query: 208 LARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 +VD + L+++ A K + C + K+ Sbjct: 161 ----GTVDARTAQKLRDVGAYSKYLTCPKTKLKI 190 >2PH3-A nrPDB Length = 245 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 60/204 (29%), Positives = 89/204 (43%), Gaps = 22/204 (10%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLS-ARNDEALRQLEAELGAERSGLRVVRVPA 68 L+TGASRG GR +A LA G L + +N E ++ E S L V Sbjct: 4 ALITGASRGIGRAIALRLA---EDGFALAIHYGQNREKAEEVAEEARRRGSPLVAVLGAN 60 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL-- 126 L AEA + A L GL L+NNAG D V + D ++ A+ Sbjct: 61 LLEAEAATALVHQAAEVL---GGLD--TLVNNAGITRDTL--LVRMKDE----DWEAVLE 109 Query: 127 -NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 NL+++ T +K + R +VNI+S+ + G A Y A KA + +A Sbjct: 110 ANLSAVFRTTREAVKLMMKAR-FGR-IVNITSVVGILGNPGQANYVASKAGLIGFTRAVA 167 Query: 186 LE--EPNVRVLNYAPGPLDTDMQQ 207 E + + V APG ++T+M + Sbjct: 168 KEYAQRGITVNAVAPGFIETEMTE 191 >2QHX-A nrPDB Length = 328 Score = 28.5 bits (62), Expect = 2.9, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 147 GLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-EP-NVRVLNYAPG 199 G N +++N+ QP G+ +Y K A + L + ALE P +RV PG Sbjct: 211 GTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG 265 >2BFA-A nrPDB Length = 288 Score = 28.5 bits (62), Expect = 3.2, Method: Compositional matrix adjust. Identities = 18/55 (32%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 147 GLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-EP-NVRVLNYAPG 199 G N +++N+ QP G+ +Y K A + L + ALE P +RV PG Sbjct: 171 GTNYSIINMVDAMTNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPG 225 >4HP8-A nrPDB Length = 247 Score = 28.1 bits (61), Expect = 3.7, Method: Compositional matrix adjust. Identities = 56/210 (26%), Positives = 90/210 (42%), Gaps = 36/210 (17%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARN--DEALRQLEAELGAERSGLRVVRVP 67 L+TGA+ G G+ +A LA + G+ +V +AR DE L + A+ G S L ++ Sbjct: 12 ALVTGANTGLGQAIAVGLA---AAGAEVVCAARRAPDETL-DIIAKDGGNASAL-LIDFA 66 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY-W-- 124 L A+ G +L+NNA G + +DS + + W Sbjct: 67 DPLAAKDSFTD-----------AGFD--ILVNNA--------GIIRRADSVEFSELDWDE 105 Query: 125 --ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +NL ++ T + K + G + VVNI+SL + Q Y A K L + Sbjct: 106 VMDVNLKALFFTTQAFAKELL-AKGRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTK 164 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLAR 210 +LA E + V APG ++T+ + R Sbjct: 165 LLANEWAAKGINVNAIAPGYIETNNTEALR 194 >1P33-A nrPDB Length = 289 Score = 27.7 bits (60), Expect = 4.6, Method: Compositional matrix adjust. Identities = 17/55 (30%), Positives = 28/55 (50%), Gaps = 2/55 (3%) Query: 147 GLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEPN--VRVLNYAPG 199 G + ++VN+ QP G+ +Y K A + L + ALE + +RV +PG Sbjct: 172 GTSYSIVNMVDAMTSQPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPG 226 >3O26-A nrPDB Length = 311 Score = 27.7 bits (60), Expect = 4.8, Method: Compositional matrix adjust. Identities = 36/143 (25%), Positives = 58/143 (40%), Gaps = 18/143 (12%) Query: 77 QQLLGALRELPRPKGLQRLLLINNAG--SLGDVSKGFVDLSDSTQVNNYWALNLTSMLCL 134 Q+L+ EL + L IN G S+ +V + LSDS ++ N + + Sbjct: 135 QELMSETYELA-----EECLKINYNGVKSVTEVLIPLLQLSDSPRIVNVSSSTGSLKYVS 189 Query: 135 TSSVLKAFPDSPGLNRTVVNISSLCALQPFK-------GW----ALYCAGKAARDMLFQV 183 + L+ D L +++ L+ FK GW A Y KA + +V Sbjct: 190 NETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKACLNAYTRV 249 Query: 184 LALEEPNVRVLNYAPGPLDTDMQ 206 LA + P +V PG + T+M Sbjct: 250 LANKIPKFQVNCVCPGLVKTEMN 272 >3A28-C nrPDB Length = 258 Score = 27.7 bits (60), Expect = 4.9, Method: Compositional matrix adjust. Identities = 52/208 (25%), Positives = 100/208 (48%), Gaps = 14/208 (6%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG ++G GR ++ LA+ +V L + ++A ++ A++ + V V Sbjct: 4 VAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIKLIEAADQ---KAVFVGL 60 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ +A + E + G +L+NNAG + + K +++++ + +++N+ Sbjct: 61 DVTDKANFDSAIDEAAE--KLGGFD--VLVNNAG-IAQI-KPLLEVTEE-DLKQIYSVNV 113 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 S+ + + F D G+ ++N +S+ A+Q F + Y K A L Q A E Sbjct: 114 FSVFFGIQAASRKF-DELGVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQEL 172 Query: 188 EPNVRVLN-YAPGPLDTDM-QQLARETS 213 P +N YAPG + T M +Q+ E S Sbjct: 173 APKGHTVNAYAPGIVGTGMWEQIDAELS 200 >3U9L-A nrPDB Length = 324 Score = 27.7 bits (60), Expect = 5.6, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 16/24 (66%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLA 28 + + + L+TGAS GFGR A LA Sbjct: 3 MSKKIILITGASSGFGRLTAEALA 26 >3U2O-A nrPDB Length = 395 Score = 27.3 bits (59), Expect = 6.7, Method: Compositional matrix adjust. Identities = 46/181 (25%), Positives = 70/181 (38%), Gaps = 28/181 (15%) Query: 21 RTLAPL----LASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA-------D 69 R L PL + ++ SP + + S + LR+L ++ ER GLR V PA D Sbjct: 199 RVLGPLADYLVVNVSSPNTAGLRSLQGKAELRRLLTKVLQERDGLRRVHRPAVLVKIAPD 258 Query: 70 LGA-----------EAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST 118 L + E G+ L+ + RP GLQ L G G K DLS T Sbjct: 259 LTSQDKEDIASVVKELGIDGLIVTNTTVSRPAGLQGALRSETGGLSG---KPLRDLSTQT 315 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 + +AL + + + + D+ R ++ L F W GK R+ Sbjct: 316 -IREMYALTQGRVPIIGVGGVSSGQDALEKIRAGASLVQLYTALTF--WGPPVVGKVKRE 372 Query: 179 M 179 + Sbjct: 373 L 373 >1UUO-A nrPDB Length = 372 Score = 26.9 bits (58), Expect = 9.5, Method: Compositional matrix adjust. Identities = 38/129 (29%), Positives = 53/129 (41%), Gaps = 26/129 (20%) Query: 21 RTLAPL----LASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA-------D 69 RTL PL + ++ SP + + S + LR L +++ ER L+ R PA D Sbjct: 176 RTLGPLADYLVVNVSSPNTAGLRSLQGKTELRHLLSKVLQERDALKGTRKPAVLVKIAPD 235 Query: 70 LGA-----------EAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST 118 L A E G+ L+ + RP GLQ L G G K DLS T Sbjct: 236 LTAQDKEDIASVARELGIDGLIVTNTTVSRPVGLQGALRSETGGLSG---KPLRDLSTQT 292 Query: 119 QVNNYWALN 127 + +AL Sbjct: 293 -IREMYALT 300 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4Z3K-A nrPDB 335 1e-92 4HWK-A nrPDB 335 1e-92 1OAA-A nrPDB 290 5e-79 2PNF-A nrPDB 222 1e-58 2C07-A nrPDB 208 2e-54 5CDY-A nrPDB 208 2e-54 2UVD-A nrPDB 207 3e-54 3RSH-A nrPDB 207 5e-54 1Q7C-A nrPDB 206 1e-53 3LYL-A nrPDB 205 2e-53 3FTP-A nrPDB 202 1e-52 4BO1-A nrPDB 199 1e-51 2GDZ-A nrPDB 197 4e-51 3EMK-A nrPDB 194 3e-50 3AUT-A nrPDB 194 5e-50 2CDH-G nrPDB 192 8e-50 3WOH-A nrPDB 192 1e-49 4CQM-B nrPDB 192 1e-49 1GEE-A nrPDB 192 2e-49 3GRP-A nrPDB 191 2e-49 3F9I-A nrPDB 190 6e-49 3O4R-A nrPDB 186 8e-48 4RZH-A nrPDB 185 2e-47 1AE1-A nrPDB 183 7e-47 4IIN-A nrPDB 182 1e-46 3D3W-A nrPDB 182 2e-46 2ZAT-A nrPDB 180 5e-46 2CFC-A nrPDB 177 5e-45 2AE2-A nrPDB 175 2e-44 1CYD-A nrPDB 175 2e-44 3KZV-A nrPDB 169 1e-42 5T5Q-A nrPDB 164 3e-41 6CI9-A nrPDB 164 4e-41 4MOW-A nrPDB 164 5e-41 3RKU-A nrPDB 164 5e-41 1HXH-A nrPDB 163 6e-41 3V2G-A nrPDB 163 7e-41 2B4Q-A nrPDB 162 2e-40 3R3S-A nrPDB 160 5e-40 3U5T-A nrPDB 159 1e-39 3WTC-A nrPDB 156 8e-39 3OIC-A nrPDB 153 7e-38 1K2W-A nrPDB 152 1e-37 3ZV3-A nrPDB 148 2e-36 5IZ4-A nrPDB 146 9e-36 2X9N-A nrPDB 142 1e-34 1SNY-A nrPDB 132 2e-31 3DWF-A nrPDB 130 8e-31 4DA9-A nrPDB 127 6e-30 Sequences not found previously or not previously below threshold: 4M8S-A nrPDB 197 4e-51 4JRO-A nrPDB 196 1e-50 3OSU-A nrPDB 190 6e-49 2HQ1-A nrPDB 183 6e-47 4CQL-A nrPDB 181 4e-46 4DMM-A nrPDB 179 8e-46 2PH3-A nrPDB 179 1e-45 2NM0-A nrPDB 169 7e-43 4DBZ-A nrPDB 167 5e-42 5ITV-A nrPDB 165 2e-41 4K6F-A nrPDB 164 3e-41 4KMS-A nrPDB 162 1e-40 4NBV-A nrPDB 159 9e-40 5B1Y-A nrPDB 159 1e-39 3EZL-A nrPDB 158 2e-39 6NRP-A nrPDB 158 3e-39 4NBT-A nrPDB 155 1e-38 1GEG-A nrPDB 155 1e-38 5OVL-A nrPDB 155 2e-38 4RZI-B nrPDB 154 5e-38 5OVJ-A nrPDB 152 2e-37 4IIV-A nrPDB 151 2e-37 3VZS-A nrPDB 151 3e-37 2Q2Q-A nrPDB 148 2e-36 5VT6-A nrPDB 147 4e-36 3OEC-A nrPDB 147 5e-36 5OJG-A nrPDB 146 7e-36 4IS3-A nrPDB 145 1e-35 1YXM-A nrPDB 144 3e-35 1NFF-A nrPDB 143 8e-35 1UZM-A nrPDB 143 8e-35 3V2H-A nrPDB 143 9e-35 5YSS-A nrPDB 141 2e-34 3W8F-A nrPDB 140 4e-34 5U9P-A nrPDB 140 8e-34 4AVY-A nrPDB 139 2e-33 4Z9Y-A nrPDB 139 2e-33 1X1T-A nrPDB 138 2e-33 3RWB-A nrPDB 138 2e-33 2HSD-A nrPDB 138 3e-33 5JS6-A nrPDB 137 5e-33 1BDB-A nrPDB 135 2e-32 3UF0-A nrPDB 135 2e-32 4TRR-A nrPDB 134 3e-32 4E6P-A nrPDB 134 3e-32 4HP8-A nrPDB 134 4e-32 1AHH-A nrPDB 134 6e-32 2EW8-A nrPDB 132 1e-31 3WYE-A nrPDB 132 2e-31 3T7C-A nrPDB 129 1e-30 1DOH-A nrPDB 129 2e-30 3UVE-A nrPDB 126 1e-29 3UN1-A nrPDB 124 5e-29 1H5Q-A nrPDB 124 5e-29 3V8B-A nrPDB 124 5e-29 2AG5-A nrPDB 123 6e-29 5ILO-A nrPDB 123 8e-29 4EGF-A nrPDB 123 1e-28 5PGZ-A nrPDB 122 2e-28 3A28-C nrPDB 121 3e-28 3OML-A nrPDB 120 5e-28 2FWM-X nrPDB 120 6e-28 1O5I-A nrPDB 119 1e-27 3GDF-A nrPDB 118 2e-27 5EJ2-A nrPDB 118 2e-27 4HBG-A nrPDB 118 2e-27 2NWQ-A nrPDB 118 3e-27 2O23-A nrPDB 118 3e-27 2HRB-A nrPDB 117 4e-27 5O3Z-A nrPDB 117 7e-27 1E3W-A nrPDB 116 8e-27 4DRY-A nrPDB 114 4e-26 2QHX-A nrPDB 111 3e-25 6CGE-A nrPDB 110 5e-25 1A27-A nrPDB 110 5e-25 2BFA-A nrPDB 110 6e-25 4CR6-A nrPDB 110 9e-25 5JY1-A nrPDB 107 4e-24 4FC7-A nrPDB 107 7e-24 3E9N-A nrPDB 106 1e-23 1P33-A nrPDB 105 3e-23 4GKB-A nrPDB 104 4e-23 3BHI-A nrPDB 101 4e-22 2BGM-A nrPDB 100 7e-22 5L51-A nrPDB 99 2e-21 3U4C-A nrPDB 97 9e-21 4RGB-A nrPDB 96 1e-20 1N5D-A nrPDB 96 2e-20 3PPI-A nrPDB 94 6e-20 3O26-A nrPDB 93 1e-19 5WQO-A nrPDB 91 4e-19 3PXX-A nrPDB 91 6e-19 1B15-A nrPDB 89 2e-18 1W73-A nrPDB 89 2e-18 5TQV-A nrPDB 88 3e-18 5LCX-A nrPDB 87 5e-18 1MG5-A nrPDB 85 3e-17 3OIG-A nrPDB 78 3e-15 5YCX-A nrPDB 76 1e-14 4M89-A nrPDB 75 3e-14 2P91-A nrPDB 75 3e-14 2YW9-A nrPDB 74 5e-14 5I9N-A nrPDB 71 5e-13 3UCF-A nrPDB 70 9e-13 5KOI-A nrPDB 70 1e-12 4NR0-A nrPDB 69 2e-12 4ZJU-A nrPDB 66 2e-11 5TF4-A nrPDB 65 2e-11 3GRK-A nrPDB 65 3e-11 3SLK-A nrPDB 64 6e-11 3U9L-A nrPDB 64 8e-11 4ALL-A nrPDB 63 1e-10 2DKN-A nrPDB 63 1e-10 3K2E-A nrPDB 60 7e-10 5CFZ-A nrPDB 60 1e-09 4JQC-A nrPDB 59 2e-09 4J3F-A nrPDB 58 3e-09 4NK4-A nrPDB 56 2e-08 1FJH-A nrPDB 53 1e-07 2PD3-A nrPDB 52 2e-07 2O2S-A nrPDB 52 3e-07 4Q9N-A nrPDB 51 5e-07 4OYR-A nrPDB 45 3e-05 3F4B-A nrPDB 45 4e-05 1ENP-A nrPDB 44 8e-05 2PTG-A nrPDB 44 9e-05 4LIS-A nrPDB 42 2e-04 2NTV-A nrPDB 41 6e-04 3RFT-A nrPDB 40 8e-04 3SXP-A nrPDB 40 9e-04 1OOE-A nrPDB 40 0.001 2O2Y-A nrPDB 40 0.001 1DIR-A nrPDB 40 0.001 2HUN-A nrPDB 40 0.001 1KEU-A nrPDB 39 0.002 5K1S-A nrPDB 39 0.003 4G5H-A nrPDB 38 0.003 4PVC-A nrPDB 38 0.003 2NNL-D nrPDB 38 0.004 2PK3-A nrPDB 38 0.005 3ORF-A nrPDB 37 0.006 6BWL-A nrPDB 36 0.016 4J6F-A nrPDB 35 0.022 1UDA-A nrPDB 35 0.024 5YWN-A nrPDB 35 0.030 2GN9-A nrPDB 35 0.038 1I3M-A nrPDB 35 0.046 3SC6-A nrPDB 34 0.063 1IE3-A nrPDB 34 0.066 4E0B-A nrPDB 34 0.068 2PZM-A nrPDB 33 0.10 2Q4B-A nrPDB 33 0.18 2Q1W-A nrPDB 32 0.19 3ENK-A nrPDB 32 0.23 4UUP-A nrPDB 32 0.24 1BXK-A nrPDB 32 0.25 3VPX-A nrPDB 32 0.26 2V6G-A nrPDB 32 0.37 1O89-A nrPDB 32 0.38 6ACF-A nrPDB 31 0.56 5N2I-A nrPDB 31 0.67 4GFJ-A nrPDB 30 1.1 4A10-A nrPDB 30 1.2 1HYE-A nrPDB 30 1.3 5A0V-A nrPDB 30 1.3 5HM5-A nrPDB 30 1.4 1R66-A nrPDB 29 1.8 3F6S-A nrPDB 29 2.1 5NUE-A nrPDB 29 2.2 5GXF-A nrPDB 29 2.4 5UZH-A nrPDB 29 2.6 5A3V-A nrPDB 28 2.9 4K28-A nrPDB 28 3.3 1VHV-A nrPDB 28 3.6 4EZI-A nrPDB 28 3.7 4UUO-A nrPDB 28 3.7 6EUG-A nrPDB 28 4.5 4Y1B-A nrPDB 28 4.5 4MIE-A nrPDB 28 4.5 3AFP-A nrPDB 28 4.5 3RUE-A nrPDB 28 4.6 3UQZ-A nrPDB 28 4.9 1WDK-C nrPDB 28 4.9 2P31-A nrPDB 28 5.3 1RK6-A nrPDB 28 5.5 5J9G-A nrPDB 28 5.6 2P8Y-T nrPDB 27 7.4 5F5N-A nrPDB 27 8.1 2Y53-A nrPDB 27 8.6 1UE7-A nrPDB 27 9.8 >4Z3K-A nrPDB Length = 275 Score = 335 bits (859), Expect = 1e-92, Method: Composition-based stats. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG Sbjct: 15 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 74 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV Sbjct: 75 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 134 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML Sbjct: 135 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 194 Query: 181 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK Sbjct: 195 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 254 Query: 241 LLSLLEKDEFKSGAHVDFYDK 261 LLSLLEKDEFKSGAHVDFYDK Sbjct: 255 LLSLLEKDEFKSGAHVDFYDK 275 >4HWK-A nrPDB Length = 288 Score = 335 bits (858), Expect = 1e-92, Method: Composition-based stats. Identities = 261/261 (100%), Positives = 261/261 (100%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG Sbjct: 28 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 87 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV Sbjct: 88 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 147 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML Sbjct: 148 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 207 Query: 181 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK Sbjct: 208 FQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 267 Query: 241 LLSLLEKDEFKSGAHVDFYDK 261 LLSLLEKDEFKSGAHVDFYDK Sbjct: 268 LLSLLEKDEFKSGAHVDFYDK 288 >1OAA-A nrPDB Length = 259 Score = 290 bits (741), Expect = 5e-79, Method: Composition-based stats. Identities = 192/257 (74%), Positives = 224/257 (87%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 GLG AVC+LTGASRGFGR LAP LA LLSPGSV+++SAR++ LRQL+ ELGA++ L+V Sbjct: 3 GLGCAVCVLTGASRGFGRALAPQLARLLSPGSVMLVSARSESMLRQLKEELGAQQPDLKV 62 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V ADLG EAG+Q+LL A+RELPRP+GLQRLLLINNA +LGDVSKGF++++D +VNNY Sbjct: 63 VLAAADLGTEAGVQRLLSAVRELPRPEGLQRLLLINNAATLGDVSKGFLNVNDLAEVNNY 122 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 WALNLTSMLCLTS L AF DSPGL++TVVNISSLCALQP+KGW LYCAGKAARDML+QV Sbjct: 123 WALNLTSMLCLTSGTLNAFQDSPGLSKTVVNISSLCALQPYKGWGLYCAGKAARDMLYQV 182 Query: 184 LALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 LA EEP+VRVL+YAPGPLD DMQQLARETS DP++R LQ+LK+ G LVDC SAQKLL Sbjct: 183 LAAEEPSVRVLSYAPGPLDNDMQQLARETSKDPELRSKLQKLKSDGALVDCGTSAQKLLG 242 Query: 244 LLEKDEFKSGAHVDFYD 260 LL+KD F+SGAHVDFYD Sbjct: 243 LLQKDTFQSGAHVDFYD 259 >2PNF-A nrPDB Length = 248 Score = 222 bits (565), Expect = 1e-58, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 108/246 (43%), Gaps = 20/246 (8%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 ME L V L+TG++RG GR +A LAS GS ++++ + E + + E+ A + G Sbjct: 1 MEIKLQGKVSLVTGSTRGIGRAIAEKLAS---AGSTVIITGTSGERAKAVAEEI-ANKYG 56 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 ++ V +L +E + + + L +L+NNAG D + L D +V Sbjct: 57 VKAHGVEMNLLSEESINKAFEEIYNLVD----GIDILVNNAGITRDKLFLRMSLLDWEEV 112 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +NLT +T + L+ +VNISS+ G Y KA Sbjct: 113 ---LKVNLTGTFLVTQNSLRKMIKQRW--GRIVNISSVVGFTGNVGQVNYSTTKAGLIGF 167 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + LA E NV V APG ++TDM + E ++++ +E G+ + A Sbjct: 168 TKSLAKELAPRNVLVNAVAPGFIETDMTAVLSE-----EIKQKYKEQIPLGRFGSPEEVA 222 Query: 239 QKLLSL 244 +L L Sbjct: 223 NVVLFL 228 >2C07-A nrPDB Length = 285 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 59/249 (23%), Positives = 105/249 (42%), Gaps = 24/249 (9%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 V L+TGA RG GR +A +LA + S ++ +R ++ + E+ + G Sbjct: 44 NKVALVTGAGRGIGREIAKMLAKSV---SHVICISRTQKSCDSVVDEI--KSFGYESSGY 98 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ + + +++ + + +L+NNAG D F+ + + + + Sbjct: 99 AGDVSKKEEISEVINKILTEHK----NVDILVNNAGITRD--NLFLRMKND-EWEDVLRT 151 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 NL S+ +T + K ++ ++NISS+ L G A Y + KA + LA Sbjct: 152 NLNSLFYITQPISKRMINNRY--GRIINISSIVGLTGNVGQANYSSSKAGVIGFTKSLAK 209 Query: 187 E--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSL 244 E N+ V APG + +DM E ++K + G++ + A L Sbjct: 210 ELASRNITVNAIAPGFISSDMTDKISE-----QIKKNIISNIPAGRMGTPEEVAN-LACF 263 Query: 245 LEKDEFKSG 253 L D KSG Sbjct: 264 LSSD--KSG 270 >5CDY-A nrPDB Length = 244 Score = 208 bits (529), Expect = 2e-54, Method: Composition-based stats. Identities = 61/248 (24%), Positives = 102/248 (41%), Gaps = 25/248 (10%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 + L+TGASRG GR +A LL + G+ ++ +A +++ + A LG GL + Sbjct: 2 SFEGKIALVTGASRGIGRAIAELL---VERGACVIGTATSEKGAEAISAYLGENGKGLML 58 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 ++ + +L +R + +L+NNAG D + + + Sbjct: 59 -----NVVDPTSIDTVLATIRAEFG----EVDILVNNAGITRD---NLLMRMKDDEWQDI 106 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 NLTS+ L+ +V++A ++ I S+ G Y A KA + Sbjct: 107 IDTNLTSVFRLSKAVMRAMMKKRF--GRIITIGSVVGTMGNAGQVNYAAAKAGVIGFSKS 164 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA E + V APG ++TDM + D R G+ +L D K A Sbjct: 165 LAREVASRGITVNVVAPGFIETDMTRTL-----TDDQRAGILAQVPANRLGDAKEIASA- 218 Query: 242 LSLLEKDE 249 ++ L DE Sbjct: 219 VAFLASDE 226 >2UVD-A nrPDB Length = 246 Score = 207 bits (527), Expect = 3e-54, Method: Composition-based stats. Identities = 58/245 (23%), Positives = 102/245 (41%), Gaps = 20/245 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+TGASRG GR +A LA +V+V A N++ ++ E+ ++ G + Sbjct: 2 LKGKVALVTGASRGIGRAIAIDLAK--QGANVVVNYAGNEQKANEVVDEI--KKLGSDAI 57 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 V AD+ + ++ ++ Q +L+NNAG D + + + Sbjct: 58 AVRADVANAEDVTNMVKQTVDVFG----QVDILVNNAGVTKD---NLLMRMKEEEWDTVI 110 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NL + T +V + + +VNI+S+ + G A Y A KA L + Sbjct: 111 NTNLKGVFLCTKAVSRFMMRQR--HGRIVNIASVVGVTGNPGQANYVAAKAGVIGLTKTS 168 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E N+ V APG + TDM + D +++ + +L + + + A + Sbjct: 169 AKELASRNITVNAIAPGFIATDMTDVL-----DENIKAEMLKLIPAAQFGEAQDIANAVT 223 Query: 243 SLLEK 247 Sbjct: 224 FFASD 228 >3RSH-A nrPDB Length = 251 Score = 207 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 59/242 (24%), Positives = 104/242 (42%), Gaps = 24/242 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+TGASRG G+ +A LLA G+ ++ +A ++ + + LG G+ + Sbjct: 10 LEGKVALVTGASRGIGKAIAELLA---ERGAKVIGTATSESGAQAISDYLGDNGKGMAL- 65 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 ++ ++ +L A+ G+ +L+NNAG D + + ++ Sbjct: 66 ----NVTNPESIEAVLKAI--TDEFGGVD--ILVNNAGITRD---NLLMRMKEEEWSDIM 114 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NLTS+ L+ +VL+ ++N+ S+ G A Y A KA + + Sbjct: 115 ETNLTSIFRLSKAVLRGMMKKR--QGRIINVGSVVGTMGNAGQANYAAAKAGVIGFTKSM 172 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E V V APG ++TDM +++ + R G+L D + A + Sbjct: 173 AREVASRGVTVNTVAPGFIETDMT-----KALNDEQRTATLAQVPAGRLGDPREIASAVA 227 Query: 243 SL 244 L Sbjct: 228 FL 229 >1Q7C-A nrPDB Length = 244 Score = 206 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 61/245 (24%), Positives = 107/245 (43%), Gaps = 25/245 (10%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + L+TGASRG GR +A LA + G+ ++ +A ++ + + LGA GL + Sbjct: 5 GKIALVTGASRGIGRAIAETLA---ARGAKVIGTATSENGAQAISDYLGANGKGLML--- 58 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 ++ A ++ +L +R + +L+NNAG D + + N+ Sbjct: 59 --NVTDPASIESVLEKIRAEFG----EVDILVNNAGITRD---NLLMRMKDEEWNDIIET 109 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 NL+S+ L+ +V++A + ++ I S+ G A + A KA + LA Sbjct: 110 NLSSVFRLSKAVMRAMMKKR--HGRIITIGSVVGTMGNGGQANFAAAKAGLIGFSKSLAR 167 Query: 187 E--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSL 244 E + V APG ++TDM + D R G+ G+L + A ++ Sbjct: 168 EVASRGITVNVVAPGFIETDMTRAL-----SDDQRAGILAQVPAGRLGGAQEIANA-VAF 221 Query: 245 LEKDE 249 L DE Sbjct: 222 LASDE 226 >3LYL-A nrPDB Length = 247 Score = 205 bits (521), Expect = 2e-53, Method: Composition-based stats. Identities = 55/250 (22%), Positives = 100/250 (40%), Gaps = 22/250 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V L+TGASRG G +A LAS G+ +V +A + + + E + + G + Sbjct: 2 SLNEKVALVTGASRGIGFEVAHALAS---KGATVVGTATSQASAEKFENSM--KEKGFKA 56 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + ++ +Q + + + L +L+NNAG D + + + Sbjct: 57 RGLVLNISDIESIQNFFAEI----KAENLAIDILVNNAGITRD---NLMMRMSEDEWQSV 109 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 NL+S+ ++ ++ +++I S+ G YCA KA + Sbjct: 110 INTNLSSIFRMSKECVRGMMKKRW--GRIISIGSVVGSAGNPGQTNYCAAKAGVIGFSKS 167 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA E N+ V APG + TDM + + + G++ + K A Sbjct: 168 LAYEVASRNITVNVVAPGFIATDMTDKL-----TDEQKSFIATKIPSGQIGEPKDIA-AA 221 Query: 242 LSLLEKDEFK 251 ++ L +E K Sbjct: 222 VAFLASEEAK 231 >3FTP-A nrPDB Length = 270 Score = 202 bits (514), Expect = 1e-52, Method: Composition-based stats. Identities = 57/246 (23%), Positives = 102/246 (41%), Gaps = 21/246 (8%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M+ L + V ++TGASRG GR +A LA G++++ +A + + A +++G Sbjct: 22 MDKTLDKQVAIVTGASRGIGRAIALELAR---RGAMVIGTATTEAGAEGIGAAF--KQAG 76 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 L ++ + L+ + + +L+NNAG D + Sbjct: 77 LEGRGAVLNVNDATAVDALVESTLKEFGA----LNVLVNNAGITQDQ---LAMRMKDDEW 129 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + NL ++ L+ +VL+ + G +VNI+S+ G Y A KA + Sbjct: 130 DAVIDTNLKAVFRLSRAVLRPMMKARG--GRIVNITSVVGSAGNPGQVNYAAAKAGVAGM 187 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + LA E + V APG +DTDM + + + L+ G+L + A Sbjct: 188 TRALAREIGSRGITVNCVAPGFIDTDMT-----KGLPQEQQTALKTQIPLGRLGSPEDIA 242 Query: 239 QKLLSL 244 + L Sbjct: 243 HAVAFL 248 >4BO1-A nrPDB Length = 269 Score = 199 bits (505), Expect = 1e-51, Method: Composition-based stats. Identities = 63/247 (25%), Positives = 104/247 (42%), Gaps = 22/247 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V L+TGASRG G+ +A L L G+V++ +A + ++ L A G+ Sbjct: 24 SLQGKVALVTGASRGIGQAIALELGRL---GAVVIGTATSASGAEKIAETLKAN--GVEG 78 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + D+ ++ + A E + Q L+++NNAG D + + + Sbjct: 79 AGLVLDVSSDES----VAATLEHIQQHLGQPLIVVNNAGITRD---NLLVRMKDDEWFDV 131 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 NL S+ L+ +VL+ + ++NI S+ G Y A KA + + Sbjct: 132 VNTNLNSLYRLSKAVLRGMTKARW--GRIINIGSVVGAMGNAGQTNYAAAKAGLEGFTRA 189 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA E + V APG +DTDM + E R+ L G+L + A K+ Sbjct: 190 LAREVGSRAITVNAVAPGFIDTDMTRELPEA-----QREALLGQIPLGRLGQAEEIA-KV 243 Query: 242 LSLLEKD 248 + L D Sbjct: 244 VGFLASD 250 >2GDZ-A nrPDB Length = 267 Score = 197 bits (501), Expect = 4e-51, Method: Composition-based stats. Identities = 62/256 (24%), Positives = 110/256 (42%), Gaps = 26/256 (10%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M + V L+TGA++G GR A L L G+ + L N EA Q +A L + Sbjct: 1 MAHMVNGKVALVTGAAQGIGRAFAEAL---LLKGAKVALVDWNLEAGVQCKAALHEQFEP 57 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + + + D+ A QQL R++ G +L+NNAG ++ Sbjct: 58 QKTLFIQCDV---ADQQQLRDTFRKVVDHFGR-LDILVNNAGV-----------NNEKNW 102 Query: 121 NNYWALNLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 +NL S++ T L + G ++N+SSL L P +YCA K Sbjct: 103 EKTLQINLVSVISGTYLGLDYMSKQNGGEGGIIINMSSLAGLMPVAQQPVYCASKHGIVG 162 Query: 180 LFQVLALEE----PNVRVLNYAPGPLDTD-MQQLARETSVDP--DMRKGLQELKAKGKLV 232 + AL VR+ PG ++T ++ + +E ++ + + ++++ ++ Sbjct: 163 FTRSAALAANLMNSGVRLNAICPGFVNTAILESIEKEENMGQYIEYKDHIKDMIKYYGIL 222 Query: 233 DCKVSAQKLLSLLEKD 248 D + A L++L+E D Sbjct: 223 DPPLIANGLITLIEDD 238 >4M8S-A nrPDB Length = 248 Score = 197 bits (500), Expect = 4e-51, Method: Composition-based stats. Identities = 53/245 (21%), Positives = 99/245 (40%), Gaps = 23/245 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L + L+TGASRG G + +L + G+ ++ +A ++ + L RV+ Sbjct: 6 LSGKIALVTGASRGIGA---AIADTLAAAGAKVIGTATSESGAAAISERLAQWGGEGRVL 62 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + ++ L+ + + + +L+NNAG D + + ++ Sbjct: 63 ----NSAEPETVENLIADIEKTFG----KLDILVNNAGITRD---NLLMRMKEEEWDDIM 111 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +NL S+ + +VL+ ++NI+S+ + G Y A KA + + Sbjct: 112 QVNLKSVFRASKAVLRGMMKQRA--GRIINITSVVGVMGNAGQTNYAAAKAGLIGFSKSM 169 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E + V APG +DTDM + E + R+ A G+ D + A +L Sbjct: 170 AREVGSRGITVNCVAPGFIDTDMTRALPE-----ETRQTFTAQTALGRFGDAQDIADAVL 224 Query: 243 SLLEK 247 L Sbjct: 225 FLASD 229 >4JRO-A nrPDB Length = 271 Score = 196 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 56/247 (22%), Positives = 92/247 (37%), Gaps = 22/247 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V ++TG SRG GR +A LA G+ + + + A+L AE G+ V Sbjct: 26 TLQGKVAVVTGGSRGIGRDIAINLAK---EGANIFFNYNGSPEAAEETAKLVAEH-GVEV 81 Query: 64 VRVPADLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 + A++ + A+ R +L+NNAG D + + ++ Sbjct: 82 EAMKANVAIAEDVDAFFKQAIERFGRVD-----ILVNNAGITRD---NLLMRMKEDEWDD 133 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +NL T +V + ++N++S+ L G A Y A KA L + Sbjct: 134 VININLKGTFLCTKAVSRTMMKQRA--GKIINMASVVGLIGNAGQANYVASKAGVIGLTK 191 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 A E + V APG + TDM E + + + G + A Sbjct: 192 TTARELAPRGINVNAVAPGFITTDMTDKLDEKTKEA-----MLAQIPLGAYGTTEDIANA 246 Query: 241 LLSLLEK 247 +L L Sbjct: 247 VLFLASD 253 >3EMK-A nrPDB Length = 246 Score = 194 bits (493), Expect = 3e-50, Method: Composition-based stats. Identities = 67/246 (27%), Positives = 103/246 (41%), Gaps = 24/246 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TGA+ G G +A L + G+++ L +E L++L AEL G R+ Sbjct: 5 LTGRKALVTGATGGLGEAIARALH---AQGAIVGLHGTREEKLKELAAEL-----GERIF 56 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 PA+L ++ L E G+ +L+NNAG D FV +SD + Sbjct: 57 VFPANLSDREAVKALGQKAEE--EMGGVD--ILVNNAGITRD--GLFVRMSDE-DWDAVL 109 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +NLTS+ LT + N ++NI+S+ + G A YCA KA + L Sbjct: 110 TVNLTSVFNLTRELTHPMMRRR--NGRIINITSIVGVTGNPGQANYCASKAGLIGFSKSL 167 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E NV V APG +++ M E D M ++ A ++ Sbjct: 168 AQEIASRNVTVNCIAPGFIESAMTGKLNEKQKDAIM-----GNIPMKRMGVGADIAAAVV 222 Query: 243 SLLEKD 248 L + Sbjct: 223 YLASDE 228 >3AUT-A nrPDB Length = 269 Score = 194 bits (492), Expect = 5e-50, Method: Composition-based stats. Identities = 60/252 (23%), Positives = 105/252 (41%), Gaps = 20/252 (7%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M L V ++TG S G GR +A V++ N+E + E+ E +G Sbjct: 9 MYTDLKDKVVVITGGSTGLGRAMAVRFGQ--EEAKVVINYYNNEEEALDAKKEV--EEAG 64 Query: 61 LRVVRVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119 + + V D+ E + L+ A++E ++INNAG V + L Sbjct: 65 GQAIIVQGDVTKEEDVVNLVQTAIKEFGTLD-----VMINNAGVENPVPSHELSL---DN 116 Query: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 N NLT + +K F ++ + V+N+SS+ + P+ + Y A K + Sbjct: 117 WNKVIDTNLTGAFLGSREAIKYFVEND-IKGNVINMSSVHEMIPWPLFVHYAASKGGMKL 175 Query: 180 LFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVS 237 + + LALE +RV N PG ++T + E DP R ++ + G + + Sbjct: 176 MTETLALEYAPKGIRVNNIGPGAMNTPINA---EKFADPVQRADVESMIPMGYIGKPEEV 232 Query: 238 AQKLLSLLEKDE 249 A + + L + Sbjct: 233 A-AVAAFLASSQ 243 >2CDH-G nrPDB Length = 244 Score = 192 bits (489), Expect = 8e-50, Method: Composition-based stats. Identities = 59/240 (24%), Positives = 99/240 (41%), Gaps = 21/240 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TGASRG G+ +A L + VLV AR+ +A ++ ++ E G + + Sbjct: 3 VVVVTGASRGIGKAIALSLGK--AGCKVLVNYARSAKAAEEVSKQI--EAYGGQAITFGG 58 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ EA ++ ++ + + +++NNAG D + +Q + LNL Sbjct: 59 DVSKEADVEAMMKTA--IDAWGTID--VVVNNAGITRDT---LLIRMKKSQWDEVIDLNL 111 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 T + T + K ++NI+S+ L G A Y A KA + A E Sbjct: 112 TGVFLCTQAATKIMMKKR--KGRIINIASVVGLIGNIGQANYAAAKAGVIGFSKTAAREG 169 Query: 188 -EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLE 246 N+ V PG + +DM E DM K + G+ + A L+ L Sbjct: 170 ASRNINVNVVCPGFIASDMTAKLGE-----DMEKKILGTIPLGRTGQPENVA-GLVEFLA 223 >3WOH-A nrPDB Length = 251 Score = 192 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 64/249 (25%), Positives = 98/249 (39%), Gaps = 23/249 (9%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G L V L+TG SRG GR +A LA +V ++ +D + ++ + E+ ER G Sbjct: 7 GALSGKVALVTGGSRGLGRAMALRLAR--DGAAVAIVYVSDDSSAKETQGEI--ERLGGT 62 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 D+ + + + A+ P +L+NNAG + D G + Sbjct: 63 ARSYRCDVSDAEQVTRCVKAVTADLGP----VDILVNNAGIIRD---GLAASIKDEDYDA 115 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 NL + F +++NISS+ + G A Y + KA L + Sbjct: 116 VMNTNLKGAFLFIKACYFGFIRKRS--GSIINISSVSGVFGSAGQANYASAKAGLIGLTK 173 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 +A E E NVR APG + TDM Q VD R + + A Sbjct: 174 SIAKELAERNVRCNAVAPGLIATDMTQDL----VDDSKR---LDPVPMRRFGRPDEVA-G 225 Query: 241 LLSLLEKDE 249 L++ L DE Sbjct: 226 LVAFLAGDE 234 >4CQM-B nrPDB Length = 244 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 60/242 (24%), Positives = 100/242 (41%), Gaps = 27/242 (11%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 VC + G SRG GR +A L+A G L + ARN E + +LG + + Sbjct: 10 KVCAVFGGSRGIGRAVAQLMAR---KGYRLAVIARNLEGAKAAAGDLGGDH-----LAFS 61 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ E +Q EL + G L+N AG D G + + + + + N Sbjct: 62 CDVAKEHDVQ---NTFEELEKHLGR-VNFLVNAAGINRD---GLLVRTKTEDMVSQLHTN 114 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 L + + ++ G ++VN+ S+ L+ G ++Y A K + LA E Sbjct: 115 LLGSMLTCKAAMRTMIQQQG--GSIVNVGSIVGLKGNSGQSVYSASKGGLVGFSRALAKE 172 Query: 188 EP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 +RV APG + TDM + +E + L++ G+ + A ++ LL Sbjct: 173 VARKKIRVNVVAPGFVHTDMTKDLKE--------EHLKKNIPLGRFGETIEVAHAVVFLL 224 Query: 246 EK 247 E Sbjct: 225 ES 226 >1GEE-A nrPDB Length = 261 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 63/252 (25%), Positives = 114/252 (45%), Gaps = 20/252 (7%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M L V ++TG+S G G+++A A+ V+V ++ + E+ ++ G Sbjct: 1 MYKDLEGKVVVITGSSTGLGKSMAIRFAT--EKAKVVVNYRSKEDEANSVLEEI--KKVG 56 Query: 61 LRVVRVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119 + V D+ E+ + L+ A++E + ++INNAG VS + LSD Sbjct: 57 GEAIAVKGDVTVESDVINLVQSAIKEFGKLD-----VMINNAGLENPVSSHEMSLSD--- 108 Query: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 N NLT + +K F ++ + TV+N+SS+ P+ + Y A K + Sbjct: 109 WNKVIDTNLTGAFLGSREAIKYFVEND-IKGTVINMSSVHEKIPWPLFVHYAASKGGMKL 167 Query: 180 LFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVS 237 + + LALE +RV N PG ++T + E DP+ R ++ + G + + + Sbjct: 168 MTETLALEYAPKGIRVNNIGPGAINTPINA---EKFADPEQRADVESMIPMGYIGEPEEI 224 Query: 238 AQKLLSLLEKDE 249 A + + L E Sbjct: 225 A-AVAAWLASSE 235 >3GRP-A nrPDB Length = 266 Score = 191 bits (485), Expect = 2e-49, Method: Composition-based stats. Identities = 54/247 (21%), Positives = 100/247 (40%), Gaps = 24/247 (9%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L L+TGA+ G G +A + G+++ L ++ L+++ A+LG + V Sbjct: 24 KLTGRKALVTGATGGIGEAIARCFH---AQGAIVGLHGTREDKLKEIAADLGKD-----V 75 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 A+L ++QL E+ + +L+NNAG D G ++ Sbjct: 76 FVFSANLSDRKSIKQL----AEVAEREMEGIDILVNNAGITRD---GLFVRMQDQDWDDV 128 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 A+NLT+ LT ++ + ++NI+S+ + G YCA KA + Sbjct: 129 LAVNLTAASTLTRELIHSMMRRRY--GRIINITSIVGVVGNPGQTNYCAAKAGLIGFSKA 186 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA E N+ V APG + + M E ++ + + ++ + A Sbjct: 187 LAQEIASRNITVNCIAPGFIKSAMTDKLNEK-----QKEAIMAMIPMKRMGIGEEIAFAT 241 Query: 242 LSLLEKD 248 + L + Sbjct: 242 VYLASDE 248 >3F9I-A nrPDB Length = 249 Score = 190 bits (482), Expect = 6e-49, Method: Composition-based stats. Identities = 57/246 (23%), Positives = 92/246 (37%), Gaps = 28/246 (11%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TGAS G G +A LL L GS +++S N+E L+ L L + + V Sbjct: 12 LTGKTSLITGASSGIGSAIARLLHKL---GSKVIISGSNEEKLKSLGNAL-KDNYTIEV- 66 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 +L + L+ L +L+ NAG D + + Sbjct: 67 ---CNLANKEECSNLISKTSNLD--------ILVCNAGITSDTLAIRM---KDQDFDKVI 112 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +NL + L +K ++NISS+ + G A YCA KA + + L Sbjct: 113 DINLKANFILNREAIKKMIQKRY--GRIINISSIVGIAGNPGQANYCASKAGLIGMTKSL 170 Query: 185 ALEE--PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 + E + V APG + +DM E R+ + + G + A + Sbjct: 171 SYEVATRGITVNAVAPGFIKSDMTDKLNEK-----QREAIVQKIPLGTYGIPEDVAYAVA 225 Query: 243 SLLEKD 248 L + Sbjct: 226 FLASNN 231 >3OSU-A nrPDB Length = 246 Score = 190 bits (482), Expect = 6e-49, Method: Composition-based stats. Identities = 51/246 (20%), Positives = 96/246 (39%), Gaps = 21/246 (8%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 L+TGASRG GR++A LA +V V A + E + E+ A+ G+ + Sbjct: 5 KSALVTGASRGIGRSIALQLAE--EGYNVAVNYAGSKEKAEAVVEEIKAK--GVDSFAIQ 60 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 A++ ++ ++ + + + L +L+NNAG D + + ++ N Sbjct: 61 ANVADADEVKAMIKEV--VSQFGSLD--VLVNNAGITRD---NLLMRMKEQEWDDVIDTN 113 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 L + ++N+SS+ G A Y A KA L + A E Sbjct: 114 LKGVFNCIQKATPQMLRQRS--GAIINLSSVVGAVGNPGQANYVATKAGVIGLTKSAARE 171 Query: 188 --EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 + V APG + +DM ++ ++++ + + A ++ L Sbjct: 172 LASRGITVNAVAPGFIVSDMTD-----ALSDELKEQMLTQIPLARFGQDTDIANT-VAFL 225 Query: 246 EKDEFK 251 D+ K Sbjct: 226 ASDKAK 231 >3O4R-A nrPDB Length = 261 Score = 186 bits (472), Expect = 8e-48, Method: Composition-based stats. Identities = 59/246 (23%), Positives = 110/246 (44%), Gaps = 18/246 (7%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+T ++ G G +A LA G+ +V+S+R + + Q A L E GL V Sbjct: 13 LANKVALVTASTDGIGFAIARRLAQ---DGAHVVVSSRKQQNVDQAVATLQGE--GLSVT 67 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 +G ++L+ +L G+ +L++NA +D+++ + Sbjct: 68 GTVCHVGKAEDRERLVATAVKL--HGGID--ILVSNAAV-NPFFGSIMDVTEEV-WDKTL 121 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N+ + +T +V+ G +VV +SS+ A P G++ Y K A L + L Sbjct: 122 DINVKAPALMTKAVVPEMEKRGG--GSVVIVSSIAAFSPSPGFSPYNVSKTALLGLTKTL 179 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A+E N+RV APG + T ++ +D + + ++E +L + + A + Sbjct: 180 AIELAPRNIRVNCLAPGLIKTSFSRML---WMDKEKEESMKETLRIRRLGEPEDCAGIVS 236 Query: 243 SLLEKD 248 L +D Sbjct: 237 FLCSED 242 >4RZH-A nrPDB Length = 247 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 61/246 (24%), Positives = 96/246 (39%), Gaps = 23/246 (9%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V L+TGASRG G+ LA + V+V A++ A + AE+ A G Sbjct: 3 ALTAQVALVTGASRGIGKA--TALALAATGMKVVVNYAQSSTAADAVVAEIIAN--GGEA 58 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + V A++ + QL+ L + + +L+NNAG D + L D Sbjct: 59 IAVQANVANADEVDQLIKT--TLDKFSRID--VLVNNAGITRDTLLLRMKLED---WQAV 111 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 LNLT + T +V K ++NI+S+ + G A Y A KA + Sbjct: 112 IDLNLTGVFLCTKAVSKLMLKQKS--GRIINITSVAGMMGNPGQANYSAAKAGVIGFTKT 169 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 +A E V V APG + TDM + + + + + + A + Sbjct: 170 VAKELASRGVTVNAVAPGFIATDMTENLN--------AEPILQFIPLARYGQPEEVAGTI 221 Query: 242 LSLLEK 247 L Sbjct: 222 RFLATD 227 >2HQ1-A nrPDB Length = 247 Score = 183 bits (465), Expect = 6e-47, Method: Composition-based stats. Identities = 47/247 (19%), Positives = 95/247 (38%), Gaps = 21/247 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TG+SRG G+ +A L ++ ++++ + +L E + +G+ VV Sbjct: 3 LKGKTAIVTGSSRGLGKAIAWKLGNM--GANIVLNGSPASTSLDATAEEF--KAAGINVV 58 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 D+ ++ ++ + + +L+NNAG D + ++ Sbjct: 59 VAKGDVKNPEDVENMVKTAMDAFG----RIDILVNNAGITRDTLMLKMS---EKDWDDVL 111 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NL S T +V K ++NI+S+ + G A Y A KA + + Sbjct: 112 NTNLKSAYLCTKAVSKIMLKQKS--GKIINITSIAGIIGNAGQANYAASKAGLIGFTKSI 169 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E + APG + TDM + + +++ + + A ++ Sbjct: 170 AKEFAAKGIYCNAVAPGIIKTDMTDVLPDK-----VKEMYLNNIPLKRFGTPEEVAN-VV 223 Query: 243 SLLEKDE 249 L D+ Sbjct: 224 GFLASDD 230 >1AE1-A nrPDB Length = 273 Score = 183 bits (464), Expect = 7e-47, Method: Composition-based stats. Identities = 58/247 (23%), Positives = 103/247 (41%), Gaps = 21/247 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L L+TG S+G G + LA L G+ + +RN++ L + E+ E+ GL V Sbjct: 18 SLKGTTALVTGGSKGIGYAIVEELAGL---GARVYTCSRNEKELDEC-LEIWREK-GLNV 72 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 DL + +L+ + + K +L+NNAG + + K D + N Sbjct: 73 EGSVCDLLSRTERDKLMQTVAHVFDGK---LNILVNNAGVV--IHKEAKDFT-EKDYNII 126 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 N + L+ S N V+ +SS+ +LY A K A + + + Sbjct: 127 MGTNFEAAYHLSQIAYPLLKASQ--NGNVIFLSSIAGFSALPSVSLYSASKGAINQMTKS 184 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELK---AKGKLVDCKVSA 238 LA E + N+RV + APG + T + + A + + P ++ + G+ + Sbjct: 185 LACEWAKDNIRVNSVAPGVILTPLVETAIKKN--PHQKEEIDNFIVKTPMGRAGKPQEV- 241 Query: 239 QKLLSLL 245 L++ L Sbjct: 242 SALIAFL 248 >4IIN-A nrPDB Length = 271 Score = 182 bits (462), Expect = 1e-46, Method: Composition-based stats. Identities = 60/244 (24%), Positives = 101/244 (41%), Gaps = 22/244 (9%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSAR-NDEALRQLEAELGAERSGLRVVR 65 L+TGAS+G G +A LAS+ G + ++ R N E L+ EL E G + Sbjct: 29 GKNVLITGASKGIGAEIAKTLASM---GLKVWINYRSNAEVADALKNEL--EEKGYKAAV 83 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 + D +E+ + A++ + + G L+NNAG + D + D ++ Sbjct: 84 IKFDAASESD---FIEAIQTIVQSDG-GLSYLVNNAGVVRDKLAIKMKTED---FHHVID 136 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 NLTS LK S +VVN++S+ + G Y A K + + A Sbjct: 137 NNLTSAFIGCREALKVMSKSRF--GSVVNVASIIGERGNMGQTNYSASKGGMIAMSKSFA 194 Query: 186 LEE--PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 E N+R + PG ++TDM + +++ + +L K A+ + Sbjct: 195 YEGALRNIRFNSVTPGFIETDMNANLK-----DELKADYVKNIPLNRLGSAKEVAEAVAF 249 Query: 244 LLEK 247 LL Sbjct: 250 LLSD 253 >3D3W-A nrPDB Length = 244 Score = 182 bits (461), Expect = 2e-46, Method: Composition-based stats. Identities = 66/249 (26%), Positives = 111/249 (44%), Gaps = 26/249 (10%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 ME L L+TGA +G GR L + G+ +V +R L L E G Sbjct: 1 MELFLAGRRVLVTGAGKGIGRGTVQALH---ATGARVVAVSRTQADLDSLV----RECPG 53 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + V V DLG ++ LG++ + LL+NNA + + F++++ Sbjct: 54 IEPVCV--DLGDWEATERALGSVGPVD--------LLVNNAAVA--LLQPFLEVTKEA-F 100 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + + +NL +++ ++ V + + G+ +VN+SS C+ + ++YC+ K A DML Sbjct: 101 DRSFEVNLRAVIQVSQIVARGLI-ARGVPGAIVNVSSQCSQRAVTNHSVYCSTKGALDML 159 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 +V+ALE +RV P + T M Q T DP K + GK + + Sbjct: 160 TKVMALELGPHKIRVNAVNPTVVMTSMGQA---TWSDPHKAKTMLNRIPLGKFAEVEHVV 216 Query: 239 QKLLSLLEK 247 +L LL Sbjct: 217 NAILFLLSD 225 >4CQL-A nrPDB Length = 261 Score = 181 bits (458), Expect = 4e-46, Method: Composition-based stats. Identities = 59/256 (23%), Positives = 97/256 (37%), Gaps = 22/256 (8%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 ++ L A+ L+TGA G GR ++ LA G+ + + A ++ LG S Sbjct: 5 LQNRLRSALALVTGAGSGIGRAVSVRLAG---EGATVAACDLDRAAAQETVRLLGGPGSK 61 Query: 61 -----LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLS 115 AD+ + LL ++ ++++ AG D F+ Sbjct: 62 EGPPRGNHAAFQADVSEARAARCLLEQVQA---CFSRPPSVVVSCAGITQD---EFLLHM 115 Query: 116 DSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKA 175 + A+NL +T + +A S G +++NISS+ G Y A KA Sbjct: 116 SEDDWDKVIAVNLKGTFLVTQAAAQALV-SNGCRGSIINISSIVGKVGNVGQTNYAASKA 174 Query: 176 ARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 233 L Q A E +R + PG + T M Q + VD + E+ G L D Sbjct: 175 GVIGLTQTAARELGRHGIRCNSVLPGFIATPMTQKVPQKVVD-----KITEMIPMGHLGD 229 Query: 234 CKVSAQKLLSLLEKDE 249 + A + L +D Sbjct: 230 PEDVADVVAFLASEDS 245 >2ZAT-A nrPDB Length = 260 Score = 180 bits (457), Expect = 5e-46, Method: Composition-based stats. Identities = 61/248 (24%), Positives = 112/248 (45%), Gaps = 22/248 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+T ++ G G +A LA G+ +V+S+R E + + A L E GL V Sbjct: 12 LENKVALVTASTDGIGLAIARRLAQ---DGAHVVVSSRKQENVDRTVATLQGE--GLSVT 66 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ--VNN 122 +G ++L+ L G+ +L++NA + F ++ D+T+ + Sbjct: 67 GTVCHVGKAEDRERLVAMAVNL--HGGVD--ILVSNAAV----NPFFGNIIDATEEVWDK 118 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +N+ + + +T +V+ G +V+ +SS+ A PF Y K A L + Sbjct: 119 ILHVNVKATVLMTKAVVPEMEKRGG--GSVLIVSSVGAYHPFPNLGPYNVSKTALLGLTK 176 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 LA+E N+RV APG + T+ Q+ +D ++ ++E +L + + A Sbjct: 177 NLAVELAPRNIRVNCLAPGLIKTNFSQVL---WMDKARKEYMKESLRIRRLGNPEDCAGI 233 Query: 241 LLSLLEKD 248 + L +D Sbjct: 234 VSFLCSED 241 >4DMM-A nrPDB Length = 269 Score = 179 bits (455), Expect = 8e-46, Method: Composition-based stats. Identities = 59/245 (24%), Positives = 93/245 (37%), Gaps = 23/245 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L + L+TGASRG GR +A LA + G+ + ++ + A Sbjct: 26 LTDRIALVTGASRGIGRAIALELA---AAGAKVAVNYASSAGAADEVVAAIAAAG-GEAF 81 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 V AD+ E+ ++ L A+ E R L +L+NNAG D + D + Sbjct: 82 AVKADVSQESEVEALFAAVIE--RWGRLD--VLVNNAGITRDTLLLRMKRDD---WQSVL 134 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 LNL + + + K ++NI+S+ G A Y A KA L + + Sbjct: 135 DLNLGGVFLCSRAAAKIMLKQRS--GRIINIASVVGEMGNPGQANYSAAKAGVIGLTKTV 192 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E + V APG + TDM + L E+ G+ + A + Sbjct: 193 AKELASRGITVNAVAPGFIATDMTSELA--------AEKLLEVIPLGRYGEAAEVAGVVR 244 Query: 243 SLLEK 247 L Sbjct: 245 FLAAD 249 >2PH3-A nrPDB Length = 245 Score = 179 bits (453), Expect = 1e-45, Method: Composition-based stats. Identities = 53/240 (22%), Positives = 94/240 (39%), Gaps = 19/240 (7%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TGASRG GR +A LA ++ + +N E ++ E S L V + A+ Sbjct: 4 ALITGASRGIGRAIALRLAE--DGFALAIHYGQNREKAEEVAEEARRRGSPL-VAVLGAN 60 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 L L+ E+ L+NNAG D + NL+ Sbjct: 61 LLEAEAATALVHQAAEVLG----GLDTLVNNAGITRDT---LLVRMKDEDWEAVLEANLS 113 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEE- 188 ++ T +K + +VNI+S+ + G A Y A KA + +A E Sbjct: 114 AVFRTTREAVKLMMKARF--GRIVNITSVVGILGNPGQANYVASKAGLIGFTRAVAKEYA 171 Query: 189 -PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 + V APG ++T+M + ++++ + G+ + A+ + L+ + Sbjct: 172 QRGITVNAVAPGFIETEMTERLP-----QEVKEAYLKQIPAGRFGRPEEVAEAVAFLVSE 226 >2CFC-A nrPDB Length = 250 Score = 177 bits (448), Expect = 5e-45, Method: Composition-based stats. Identities = 59/250 (23%), Positives = 105/250 (42%), Gaps = 16/250 (6%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 V ++TGAS G G +A + + L LSA E + A+ +V+RV Sbjct: 3 RVAIVTGASSGNGLAIATRFLARGDRVAALDLSAETLEETARTHWHAYAD----KVLRVR 58 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 AD+ E + + A E +L+NNAG G+ G + + Q + A+N Sbjct: 59 ADVADEGDVNAAIAATMEQFGA----IDVLVNNAGITGNSEAGVLHTTPVEQFDKVMAVN 114 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 + + +VL +VNI+S+ +L F G + Y K A L + +A++ Sbjct: 115 VRGIFLGCRAVLPHMLLQGA--GVIVNIASVASLVAFPGRSAYTTSKGAVLQLTKSVAVD 172 Query: 188 EP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 +R PG ++T M Q + P++R + + ++ A ++ L Sbjct: 173 YAGSGIRCNAVCPGMIETPMTQWRLDQ---PELRDQVLARIPQKEIGTAAQVADAVMFLA 229 Query: 246 EKD-EFKSGA 254 +D + +GA Sbjct: 230 GEDATYVNGA 239 >2AE2-A nrPDB Length = 260 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 66/246 (26%), Positives = 106/246 (43%), Gaps = 23/246 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS-GLRV 63 L L+TG SRG G + LASL G+ + +RN ++L L RS G +V Sbjct: 7 LEGCTALVTGGSRGIGYGIVEELASL---GASVYTCSRNQ---KELNDCLTQWRSKGFKV 60 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 DL + + Q+L+ + K +L+NNAG + + K D + + Sbjct: 61 EASVCDLSSRSERQELMNTVANHFHGK---LNILVNNAGIV--IYKEAKDYTVE-DYSLI 114 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 ++N + L+ S VV ISS+ A+Y A K A D L + Sbjct: 115 MSINFEAAYHLSVLAHPFLKASER--GNVVFISSVSGALAVPYEAVYGATKGAMDQLTRC 172 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELK---AKGKLVDCKVSA 238 LA E + N+RV PG + T + ++ T DP+ ++ L +L A ++ + K A Sbjct: 173 LAFEWAKDNIRVNGVGPGVIATSLVEM---TIQDPEQKENLNKLIDRCALRRMGEPKELA 229 Query: 239 QKLLSL 244 + L Sbjct: 230 AMVAFL 235 >1CYD-A nrPDB Length = 244 Score = 175 bits (443), Expect = 2e-44, Method: Composition-based stats. Identities = 62/249 (24%), Positives = 111/249 (44%), Gaps = 26/249 (10%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M+ L+TGA +G GR L + G+ +V R + L L E G Sbjct: 1 MKLNFSGLRALVTGAGKGIGRDTVKALH---ASGAKVVAVTRTNSDLVSLA----KECPG 53 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + V V DLG ++ LG + + LL+NNA + + + F++++ Sbjct: 54 IEPVCV--DLGDWDATEKALGGIGPVD--------LLVNNAALV--IMQPFLEVTKEA-F 100 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + +++NL S+ ++ V + + G+ ++VN+SS+ A F Y + K A ML Sbjct: 101 DRSFSVNLRSVFQVSQMVARDMI-NRGVPGSIVNVSSMVAHVTFPNLITYSSTKGAMTML 159 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + +A+E +RV + P + TDM ++ S DP+ + L+E K + + Sbjct: 160 TKAMAMELGPHKIRVNSVNPTVVLTDM---GKKVSADPEFARKLKERHPLRKFAEVEDVV 216 Query: 239 QKLLSLLEK 247 +L LL Sbjct: 217 NSILFLLSD 225 >2NM0-A nrPDB Length = 253 Score = 169 bits (429), Expect = 7e-43, Method: Composition-based stats. Identities = 54/241 (22%), Positives = 82/241 (34%), Gaps = 32/241 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG +RG G +A A G + ++ R+ E + V D Sbjct: 24 VLVTGGNRGIGLAIARAFA---DAGDKVAITYRSGEPPEGF-------------LAVKCD 67 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + ++Q + E P +LI NAG D + + NLT Sbjct: 68 ITDTEQVEQAYKEIEETHGP----VEVLIANAGVTKDQ---LLMRMSEEDFTSVVETNLT 120 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 + +A VV ISS+ L G A Y A KA + LA E Sbjct: 121 GTFRVVKRANRAML--RAKKGRVVLISSVVGLLGSAGQANYAASKAGLVGFARSLARELG 178 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 N+ APG +DTDM ++ + R + G+ + A + L Sbjct: 179 SRNITFNVVAPGFVDTDMTKVL-----TDEQRANIVSQVPLGRYARPEEIAATVRFLASD 233 Query: 248 D 248 D Sbjct: 234 D 234 >3KZV-A nrPDB Length = 254 Score = 169 bits (427), Expect = 1e-42, Method: Composition-based stats. Identities = 71/236 (30%), Positives = 109/236 (46%), Gaps = 19/236 (8%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 V L+TG SRG G+++ +L SL +V+ AR++ L++L+ E+ G R V Sbjct: 2 GKVILVTGVSRGIGKSIVDVLFSL-DKDTVVYGVARSEAPLKKLK-----EKYGDRFFYV 55 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ ++ L+QL+ A + + L+ NAG L V V+ D + + Sbjct: 56 VGDITEDSVLKQLVNAAVK----GHGKIDSLVANAGVLEPVQN--VNEIDVNAWKKLYDI 109 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 N S++ L L N VV +SS F W Y + KAA + LA Sbjct: 110 NFFSIVSLVGIALPELKK---TNGNVVFVSSDACNMYFSSWGAYGSSKAALNHFAMTLAN 166 Query: 187 EEPNVRVLNYAPGPLDTDMQQLARE----TSVDPDMRKGLQELKAKGKLVDCKVSA 238 EE V+ + APG +DTDMQ RE +S+ + K + LK +L+D V A Sbjct: 167 EERQVKAIAVAPGIVDTDMQVNIRENVGPSSMSAEQLKMFRGLKENNQLLDSSVPA 222 >4DBZ-A nrPDB Length = 281 Score = 167 bits (422), Expect = 5e-42, Method: Composition-based stats. Identities = 62/248 (25%), Positives = 95/248 (38%), Gaps = 20/248 (8%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 V L+TGA+ G G +A L G + + AR +E LR EL +G+ Sbjct: 25 DSEVALVTGATSGIGLEIARRLGK---EGLRVFVCARGEEGLRTTLKEL--REAGVEADG 79 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 D+ + ++ L+ A+ E P +L+NNAG +L+D + Sbjct: 80 RTCDVRSVPEIEALVAAVVERYGP----VDVLVNNAG--RPGGGATAELADEL-WLDVVE 132 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 NLT + +T VLKA +VNI+S Q A Y A K + L Sbjct: 133 TNLTGVFRVTKQVLKAGGMLERGTGRIVNIASTGGKQGLVHAAPYSASKHGVVGFTKALG 192 Query: 186 LEEP--NVRVLNYAPGPLDTDMQQLARETSVD------PDMRKGLQELKAKGKLVDCKVS 237 LE + V PG ++T M RE D + + G+ V Sbjct: 193 LELARTGITVNAVCPGFVETPMAASVREHYSDIWEVSTEEAFDRITARVPIGRYVQPSEV 252 Query: 238 AQKLLSLL 245 A+ + L+ Sbjct: 253 AEMVAYLI 260 >5ITV-A nrPDB Length = 255 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 51/252 (20%), Positives = 97/252 (38%), Gaps = 21/252 (8%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M L L+TG + G G + +V++ ++ + + + Sbjct: 1 MIMNLTDKTVLITGGASGIGYAAVQAFLGQQ---ANVVVADIDEAQGEAMV----RKENN 53 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 R+ V D+ EA Q + + + GL +LINNAG ++LSD Sbjct: 54 DRLHFVQTDITDEAACQHAVESA--VHTFGGLD--VLINNAGIEIVAPIHEMELSD---W 106 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 N +NLT M ++ LK + ++N S+ L + Y A K L Sbjct: 107 NKVLQVNLTGMFLMSKHALKHMLAAG--KGNIINTCSVGGLVAWPDIPAYNASKGGVLQL 164 Query: 181 FQVLALEEPN--VRVLNYAPGPLDTDMQQLARETSVD---PDMRKGLQELKAKGKLVDCK 235 + +A++ +RV PG +DT + + + + + +++K ++ +L + Sbjct: 165 TKSMAVDYAKHQIRVNCVCPGIIDTPLNEKSFLENNEGTLEEIKKEKAKVNPLLRLGKPE 224 Query: 236 VSAQKLLSLLEK 247 A +L L Sbjct: 225 EIANVMLFLASD 236 >4K6F-A nrPDB Length = 255 Score = 164 bits (416), Expect = 3e-41, Method: Composition-based stats. Identities = 58/256 (22%), Positives = 100/256 (39%), Gaps = 22/256 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 + + + ++TG G G ++ L V+V + N+ + E+ A +G Sbjct: 9 MTKRIAVVTGGMGGLGEAVSIRLNDAGHR--VVVTYSPNNTGADRWLTEMHA--AGREFH 64 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 P D+ QQ + + P +L+NNAG D++ + D + Sbjct: 65 AYPVDVADHDSCQQCIEKIVRDVGP----VDILVNNAGITRDMT---LRKLDKVNWDAVI 117 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NL S+ +T V + +VNISS+ + G Y A KA + L Sbjct: 118 RTNLDSVFNMTKPVCDGMVERGW--GRIVNISSVNGSKGSVGQTNYAAAKAGMHGFTKSL 175 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 ALE V V +PG L T M + +D + G+L + A L+ Sbjct: 176 ALEIARKGVTVNTVSPGYLATKMVTAIPQDILD----TKILPQIPAGRLGKPEEVA-ALV 230 Query: 243 SLLEKDE--FKSGAHV 256 + L +E F +G+++ Sbjct: 231 AYLCSEEAGFVTGSNI 246 >5T5Q-A nrPDB Length = 247 Score = 164 bits (415), Expect = 3e-41, Method: Composition-based stats. Identities = 61/245 (24%), Positives = 104/245 (42%), Gaps = 23/245 (9%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M+ +LTGA+ G GR +A L + G+ LVL+ + E L A LG+ Sbjct: 3 MKFEFENRTLVLTGANGGIGRAIAELFH---ASGANLVLTDLDREGLDAFAASLGSPE-- 57 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 R+ + AD + ++ + E R G+ L+ +AG +K F ++SD Sbjct: 58 -RIATIKADASSADDAEKTVALAME--RFGGID--FLVPSAGIYQ--AKPFAEMSD-ADW 109 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + ++NL + L L A + + ++V ++SL A + A Y A K A + Sbjct: 110 HRTISINLDGVFYLCKRALPALKE----DSSIVTLASLAAYRGAYVNAHYGATKGAMVSM 165 Query: 181 FQVLALE-EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQ 239 + L+ E P RV +PG ++T M +T +D M + +L A Sbjct: 166 TRALSRELAPKTRVNGVSPGIIETPMTSELLKTRMDETMTQT-----PLKRLGKPSEIAS 220 Query: 240 KLLSL 244 + L Sbjct: 221 VIAFL 225 >6CI9-A nrPDB Length = 259 Score = 164 bits (415), Expect = 4e-41, Method: Composition-based stats. Identities = 55/250 (22%), Positives = 96/250 (38%), Gaps = 20/250 (8%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M L ++TG S+G GR +A A+ G +V++ RN + L + A+L R Sbjct: 3 MFTSLEGRSAIVTGGSKGIGRGIAETFAN---AGVDVVITGRNQDDLDRTVADLSGTR-- 57 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 +V V AD+ ++ + + R GL ++ NAG G ++ + Sbjct: 58 GKVTAVRADVTDPEDARRTVA--ETVSRHGGLD--IVCANAGIF---PSGRLEDLTPDDI 110 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +N + + + L+A S G R VV S + + GW+ Y A KAA+ Sbjct: 111 EQVLGVNFKGTVYIVQAALQALTAS-GHGRVVVTSSITGPITGYPGWSHYGASKAAQLGF 169 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + A+E + + PG + M + E + D + G+L Sbjct: 170 LRTAAMELAPKKITINAVLPGNI---MTEGLDE--MGQDYLDQMASAIPAGRLGSVADIG 224 Query: 239 QKLLSLLEKD 248 L + Sbjct: 225 NAALFFATDE 234 >4MOW-A nrPDB Length = 256 Score = 164 bits (414), Expect = 5e-41, Method: Composition-based stats. Identities = 59/256 (23%), Positives = 102/256 (39%), Gaps = 20/256 (7%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V ++TGAS+G G +A LA +V+V A + + + + +G R Sbjct: 11 KLAGKVAIVTGASKGIGAAIAKALA--DEGAAVVVNYASSKAGADAVVSAI--TEAGGRA 66 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V V D+ A Q+++ E + +L+NN+G ++ Sbjct: 67 VAVGGDVSKAADAQRIVDTAIETYG----RLDVLVNNSGVYEFAP---IEAITEEHYRRQ 119 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 + N+ +L T + +K G +++NISS+ A+Y K A D + V Sbjct: 120 FDTNVFGVLLTTQAAVKHL----GEGASIINISSVVTSITPPASAVYSGTKGAVDAITGV 175 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LALE +RV PG + T+ A D + + G+L + A Sbjct: 176 LALELGPRKIRVNAINPGMIVTEGTHSAGIIGSDLE--AQVLGQTPLGRLGEPNDIASVA 233 Query: 242 LSLLEKD-EFKSGAHV 256 + L D + +G H+ Sbjct: 234 VFLASDDARWMTGEHL 249 >3RKU-A nrPDB Length = 287 Score = 164 bits (414), Expect = 5e-41, Method: Composition-based stats. Identities = 49/204 (24%), Positives = 89/204 (43%), Gaps = 10/204 (4%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L + L+TGAS G G+ A + L+L+AR E L +L+ + E +V Sbjct: 31 LAKKTVLITGASAGIGKATALEYLEASNGDMKLILAARRLEKLEELKKTIDQEFPNAKVH 90 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 D+ ++ + L + + +L+NNAG + V + + + + Sbjct: 91 VAQLDITQAEKIKPFIENLPQEFK----DIDILVNNAG--KALGSDRVGQIATEDIQDVF 144 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 N+T+++ +T +VL F +VN+ S+ + ++YCA K A L Sbjct: 145 DTNVTALINITQAVLPIFQAKNS--GDIVNLGSIAGRDAYPTGSIYCASKFAVGAFTDSL 202 Query: 185 ALEEPN--VRVLNYAPGPLDTDMQ 206 E N +RV+ APG ++T+ Sbjct: 203 RKELINTKIRVILIAPGLVETEFS 226 >1HXH-A nrPDB Length = 253 Score = 163 bits (413), Expect = 6e-41, Method: Composition-based stats. Identities = 65/249 (26%), Positives = 106/249 (42%), Gaps = 23/249 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+TG + G G + LL L G+ + S N+ A +QL AEL G R + Sbjct: 4 LQGKVALVTGGASGVGLEVVKLL---LGEGAKVAFSDINEAAGQQLAAEL-----GERSM 55 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 V D+ +EA ++ A++ +L+NNAG L L D + Sbjct: 56 FVRHDVSSEADWTLVMAAVQRRLGT----LNVLVNNAGILLPGDMETGRLED---FSRLL 108 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N S+ + A + +++N++S+ + P + +A Y A KAA L + Sbjct: 109 KINTESVFIGCQQGIAAMKE---TGGSIINMASVSSWLPIEQYAGYSASKAAVSALTRAA 165 Query: 185 AL----EEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 AL + +RV + P + T M Q + V +M +L G+ + AQ Sbjct: 166 ALSCRKQGYAIRVNSIHPDGIYTPMMQASLPKGVSKEMVLHDPKLNRAGRAYMPERIAQ- 224 Query: 241 LLSLLEKDE 249 L+ L DE Sbjct: 225 LVLFLASDE 233 >3V2G-A nrPDB Length = 271 Score = 163 bits (413), Expect = 7e-41, Method: Composition-based stats. Identities = 67/257 (26%), Positives = 106/257 (41%), Gaps = 27/257 (10%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 L +TG SRG G +A LA L +V + E + + +E+ E++G R Sbjct: 27 ISLAGKTAFVTGGSRGIGAAIAKRLA--LEGAAVALTYVNAAERAQAVVSEI--EQAGGR 82 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 V + AD ++Q A+RE G +L+N+AG ++D + Sbjct: 83 AVAIRADNRDAEAIEQ---AIRETVEALG-GLDILVNSAGIWHSAPLEETTVAD---FDE 135 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISS-LCALQPFKGWALYCAGKAARDMLF 181 A+N + S + G ++ I S L L P+ G +LY A KAA L Sbjct: 136 VMAVNFRAPFVAIRSASRHL----GDGGRIITIGSNLAELVPWPGISLYSASKAALAGLT 191 Query: 182 QVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQ 239 + LA + + V PG DTDM D D + +E A G + + A Sbjct: 192 KGLARDLGPRGITVNIVHPGSTDTDMNP------ADGDHAEAQRERIATGSYGEPQDIA- 244 Query: 240 KLLSLLE--KDEFKSGA 254 L++ L + +F +GA Sbjct: 245 GLVAWLAGPQGKFVTGA 261 >4KMS-A nrPDB Length = 249 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 56/243 (23%), Positives = 103/243 (42%), Gaps = 24/243 (9%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 + ++TG +RG G+ A L + +V+ N +A +++E E+ G++ Sbjct: 11 EIAIVTGGTRGIGKATALELKN--KGLTVVANFFSNYDAAKEME-----EKYGIKTKCW- 62 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 ++ +Q + + E + +L+NNAG D + D N+ +N Sbjct: 63 -NVADFEECRQAVKEIEEEFKK---PVSILVNNAGITKDKMLHRMSHQD---WNDVINVN 115 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 L S ++SSV++ + +VNISS+ A G Y A KA + LA E Sbjct: 116 LNSCFNMSSSVMEQMRNQDY--GRIVNISSINAQAGQVGQTNYSAAKAGIIGFTKALARE 173 Query: 188 --EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 N+ V APG + T+M E D+ + K +L + A+ + L+ Sbjct: 174 TASKNITVNCIAPGYIATEMVGAVPE-----DVLAKIINSIPKKRLGQPEEIARAVAFLV 228 Query: 246 EKD 248 +++ Sbjct: 229 DEN 231 >2B4Q-A nrPDB Length = 276 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 67/246 (27%), Positives = 100/246 (40%), Gaps = 21/246 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L + L+TG SRG G+ +A LL G+ + + AR+ EA L A Sbjct: 26 SLAGRIALVTGGSRGIGQMIAQ---GLLEAGARVFICARDAEACADTATRLSAY---GDC 79 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 +PADL +EAG ++L AL EL + +L+NNAG+ + +S Sbjct: 80 QAIPADLSSEAGARRLAQALGELSA----RLDILVNNAGTSWGAALESYPVSG---WEKV 132 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGL--NRTVVNISSLCALQPFKGWA-LYCAGKAARDML 180 LN+TS+ +L S V+NI S+ + A Y KAA L Sbjct: 133 MQLNVTSVFSCIQQLLPLLRRSASAENPARVINIGSVAGISAMGEQAYAYGPSKAALHQL 192 Query: 181 FQVLALEEPN--VRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 ++LA E + V APG + M R + DP + G+ + A Sbjct: 193 SRMLAKELVGEHINVNVIAPGRFPSRMT---RHIANDPQALEADSASIPMGRWGRPEEMA 249 Query: 239 QKLLSL 244 +SL Sbjct: 250 ALAISL 255 >3R3S-A nrPDB Length = 294 Score = 160 bits (405), Expect = 5e-40, Method: Composition-based stats. Identities = 66/256 (25%), Positives = 105/256 (41%), Gaps = 18/256 (7%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G L L+TG G GR A A + ++ L A +E +Q++A + E G + Sbjct: 45 GRLKDRKALVTGGDSGIGRAAAIAYAREGADVAINYLPA-EEEDAQQVKALI--EECGRK 101 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 V +P DL E+ + L+ RE GL L L+ AG + DL+ S Q Sbjct: 102 AVLLPGDLSDESFARSLVHKAREA--LGGLDILALV--AGKQTAIP-EIKDLT-SEQFQQ 155 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +A+N+ ++ +T + P +++ SS+ A QP Y A KAA + Sbjct: 156 TFAVNVFALFWITQEAIPLLPK----GASIITTSSIQAYQPSPHLLDYAATKAAILNYSR 211 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 LA + E +RV APGP+ T +Q +T D + + A Sbjct: 212 GLAKQVAEKGIRVNIVAPGPIWTALQISGGQTQ---DKIPQFGQQTPMKRAGQPAELAPV 268 Query: 241 LLSLLEKDEFKSGAHV 256 + L ++ A V Sbjct: 269 YVYLASQESSYVTAEV 284 >4NBV-A nrPDB Length = 246 Score = 159 bits (403), Expect = 9e-40, Method: Composition-based stats. Identities = 53/247 (21%), Positives = 92/247 (37%), Gaps = 21/247 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V ++TGA+ G G A A G+++VL + +R+ A L A + + Sbjct: 2 KLQGRVAIITGAAAGIGFATAQRFA---EDGAIVVLCDVQEARVREAAARLAATGATVSA 58 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 RV D+ + ++ A+ + + +L+NNAG D + Q + Sbjct: 59 YRV--DVTRRDEVDAMVAAVLAAHQ----RVDILVNNAGITKDAR---LAKMTEAQFDAV 109 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NL + +V + ++N SS+ L G Y A K + Sbjct: 110 IDVNLKGVFNCAQAVAGLMTEQG--KGVILNASSVVGLYGNFGQTNYAASKFGVIGFTKT 167 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 A E VRV PG ++T++ Q + +D G+ +L + A Sbjct: 168 WARELGPKGVRVNAVCPGFVNTEILQTVPDKVLD-----GMTSSCWLRRLAEPAEIASIY 222 Query: 242 LSLLEKD 248 L D Sbjct: 223 AFLASDD 229 >3U5T-A nrPDB Length = 267 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 54/245 (22%), Positives = 95/245 (38%), Gaps = 23/245 (9%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 V ++TGASRG G +A LAS +V++ A A ++ ++ E +G + + Sbjct: 27 NKVAIVTGASRGIGAAIAARLAS--DGFTVVINYAGKAAAAEEVAGKI--EAAGGKALTA 82 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 AD+ A +++L E +L+NNAG + + + + A+ Sbjct: 83 QADVSDPAAVRRLFATAEEAFG----GVDVLVNNAGIM---PLTTIAETGDAVFDRVIAV 135 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNIS-SLCALQPFKGWALYCAGKAARDMLFQVLA 185 NL + ++N+S S L + +Y A KA + + VL+ Sbjct: 136 NLKGTFNTLREAA----QRLRVGGRIINMSTSQVGLL-HPSYGIYAAAKAGVEAMTHVLS 190 Query: 186 LEEPN--VRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 E + V APGP TD+ ++R +L +L + A + Sbjct: 191 KELRGRDITVNAVAPGPTATDL----FLEGKSDEVRDRFAKLAPLERLGTPQDIAGAVAF 246 Query: 244 LLEKD 248 L D Sbjct: 247 LAGPD 251 >5B1Y-A nrPDB Length = 270 Score = 159 bits (402), Expect = 1e-39, Method: Composition-based stats. Identities = 55/238 (23%), Positives = 98/238 (41%), Gaps = 18/238 (7%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG SRG GR A G +V++ ++ L + AE V D Sbjct: 26 ALVTGGSRGIGRATVLRFAR---EGWSVVIAYKSRADLAEKTAEEARRLGSPEAYTVRVD 82 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 +G + ++ + EL +L+N AG L G ++ + ++ +NLT Sbjct: 83 VGDPDSVTEMSSRVGELIPH----LNVLVNAAGVLQ---LGGIEETSISEWEETLRVNLT 135 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFK-GWALYCAGKAARDMLFQVLA--L 186 + +T +L + ++VN++S+ Y A KA L + LA L Sbjct: 136 GVYLVTKLLLPLLRKAKWA--SIVNVASIAGETGNVVAGVAYSASKAGVIGLTKRLAVQL 193 Query: 187 EEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSL 244 +RV AP ++TDM + +T P+ R+ + L ++ + A+ +L L Sbjct: 194 AGYGIRVNAVAPSFVETDMTRSFLDT---PEKRERIASLHPLKIILKPEDVAEAILFL 248 >3EZL-A nrPDB Length = 256 Score = 158 bits (400), Expect = 2e-39, Method: Composition-based stats. Identities = 51/254 (20%), Positives = 92/254 (36%), Gaps = 23/254 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 + + + +TG G G ++ L V+ N + R+++ + G Sbjct: 11 MSQRIAYVTGGMGGIGTSICQRLHK--DGFRVVAGCGPN--SPRRVKWLEDQKALGFDFY 66 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 ++G +Q + + + + +L+NNAG DV Sbjct: 67 ASEGNVGDWDSTKQAFDKV----KAEVGEIDVLVNNAGITRDV---VFRKMTREDWQAVI 119 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 NLTS+ +T V+ + ++NISS+ + G Y KA L Sbjct: 120 DTNLTSLFNVTKQVIDGMVERGW--GRIINISSVNGQKGQFGQTNYSTAKAGIHGFTMSL 177 Query: 185 ALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E V V +PG + TDM + R PD+ + + +L ++ Sbjct: 178 AQEVATKGVTVNTVSPGYIGTDMVKAIR-----PDVLEKIVATIPVRRLGSPDEIG-SIV 231 Query: 243 SLLEKDE--FKSGA 254 + L +E F +GA Sbjct: 232 AWLASEESGFSTGA 245 >6NRP-A nrPDB Length = 263 Score = 158 bits (399), Expect = 3e-39, Method: Composition-based stats. Identities = 52/242 (21%), Positives = 101/242 (41%), Gaps = 25/242 (10%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEA-LRQLEAELGAERSGLRVVRVPAD 69 L+TG+SRG G+ +A LA G + + AR+ +A Q+ E+ A G + D Sbjct: 28 LVTGSSRGIGKAIALQLAK---AGFDVTVHARSRQAEAEQVVQEIQA--LGQNSHYLMFD 82 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + +QQ+L +++ + G ++L NAG D + + + + +L Sbjct: 83 VNERQTVQQILE--QDVEQHGGFYGVVL--NAGLTHDGAFPALT---DQDWDEVISTSLD 135 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 + ++ +V +SS+ + +G Y A KA + LALE Sbjct: 136 GFYNVLKPLIMPMIHLRK-GGRIVTLSSVSGIMGNRGQVNYSAAKAGLIGATKALALELA 194 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 + + V APG ++T+M V ++++ ++ ++ A ++ L Sbjct: 195 KRKITVNCVAPGLIETEM--------VTDEVKEHALKMIPLQRMGQVDEVA-SVVKFLCS 245 Query: 248 DE 249 DE Sbjct: 246 DE 247 >3WTC-A nrPDB Length = 262 Score = 156 bits (395), Expect = 8e-39, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 100/254 (39%), Gaps = 23/254 (9%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L + +TGA++G G+ +A LA G+ ++L + L + E+ E G R Sbjct: 5 SLSGKIAAVTGAAQGIGKAIALRLAK---DGADVILLDVKQDTLAETAKEV--EALGRRA 59 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V + AD+ + L + +++NNAG K +D+ ++ Sbjct: 60 VALTADISNRDQFRSTLADAAKTLG----GLDIMVNNAGICQ--VKPILDIEP-AEIEKI 112 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +++N+ +L + F + G ++N S+ + + Y A K A L Q Sbjct: 113 FSINVQGVLWGMQAAATLFKEK-GTKGKIINACSIAGHEGYPLLGAYSATKFAVRALTQS 171 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARE-------TSVDPDMRKGLQELKAKGKLVDC 234 A E + V +Y PG + TDM + T + +K ++ A G++ Sbjct: 172 AAKELASSGITVNSYCPGIVGTDMWVTIDKRMAEITGTEIGATYKKYVEG-IALGRVETA 230 Query: 235 KVSAQKLLSLLEKD 248 A + L D Sbjct: 231 DDVAGFVAYLSSSD 244 >4NBT-A nrPDB Length = 240 Score = 155 bits (393), Expect = 1e-38, Method: Composition-based stats. Identities = 53/250 (21%), Positives = 94/250 (37%), Gaps = 32/250 (12%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 L V ++TG ++G G+ +A A G+ ++ +L + Sbjct: 2 KKLEGKVAVITGGAKGLGQAIALAYA---EEGAKVIAGD---------LGDLTYSHPNVE 49 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 + + ++ G+++ ++ + + + +L+NNAG D Q + Sbjct: 50 GMYL--NVTDVTGVEKFYQSV--IDKYGKID--ILVNNAGITKDA---MTRKMTEAQWDA 100 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +NL + LT V + +++NISS+ + G A Y A KA L Sbjct: 101 VIDVNLKGVFNLTRLVGPQMQTNGY--GSIINISSVVGVFGNIGQANYAATKAGVIGLTM 158 Query: 183 VLALE----EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 A E NVRV APG + TD+ +V D+ L +L + A Sbjct: 159 TWAKEFALKGANVRVNAIAPGYIMTDIL-----KTVPQDLLDKFAALTMLNRLGQPEEIA 213 Query: 239 QKLLSLLEKD 248 + L L D Sbjct: 214 KVALFLASDD 223 >1GEG-A nrPDB Length = 256 Score = 155 bits (392), Expect = 1e-38, Method: Composition-based stats. Identities = 48/251 (19%), Positives = 94/251 (37%), Gaps = 21/251 (8%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + V L+TGA +G G+ +A L G + ++ ND + + +E+ ++G V V Sbjct: 2 KKVALVTGAGQGIGKAIALRLVK---DGFAVAIADYNDATAKAVASEI--NQAGGHAVAV 56 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ + + R+ +++NNAG S ++ V+ + + Sbjct: 57 KVDVSDRDQVFAAVEQARKTLG----GFDVIVNNAGVAP--STPIESITPEI-VDKVYNI 109 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 N+ ++ + ++AF G ++N S A+Y + K A L Q A Sbjct: 110 NVKGVIWGIQAAVEAF-KKEGHGGKIINACSQAGHVGNPELAVYSSSKFAVRGLTQTAAR 168 Query: 187 EEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMR------KGLQELKAKGKLVDCKVSA 238 + + V Y PG + T M + + + G+L + + A Sbjct: 169 DLAPLGITVNGYCPGIVKTPMWAEIDRQVSEAAGKPLGYGTAEFAKRITLGRLSEPEDVA 228 Query: 239 QKLLSLLEKDE 249 + L D Sbjct: 229 ACVSYLASPDS 239 >5OVL-A nrPDB Length = 300 Score = 155 bits (392), Expect = 2e-38, Method: Composition-based stats. Identities = 47/241 (19%), Positives = 83/241 (34%), Gaps = 32/241 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG +RG G +A LA + G + ++ R A L V D Sbjct: 71 VLVTGGNRGIGLAIARRLA---ADGHKVAVTHRGSGAPDDL-------------FGVQCD 114 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + A + + + E P +L+ NAG D F+ + NLT Sbjct: 115 VTDSAAVDRAFKEVEEHQGP----VEVLVANAGISKDA---FLMRMTEERFEEVINTNLT 167 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 + ++ I S+ + A Y A KA + + ++ E Sbjct: 168 GAFRCAQRASRTMQRKRF--GRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELA 225 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 + V APG +DT+M + D ++ G + ++ + A + L + Sbjct: 226 KAGVTANVVAPGYIDTEMTRAL-----DERIQAGALDFIPAKRVGTAEEVAGAVSFLASE 280 Query: 248 D 248 D Sbjct: 281 D 281 >4RZI-B nrPDB Length = 240 Score = 154 bits (388), Expect = 5e-38, Method: Composition-based stats. Identities = 52/248 (20%), Positives = 92/248 (37%), Gaps = 31/248 (12%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 + GL V ++TG +RG G + LL + G+ + + +L + Sbjct: 2 LSLGLEDKVIVVTGGNRGIGAAIVKLLQEM---GAKVAFT------------DLATDGGN 46 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + V A++ L+ + A E+ G + + NAG D F Sbjct: 47 TEALGVVANVTD---LESMTAAAAEITDKLGPVYGV-VANAGITKD---NFFPKLTPADW 99 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + +NL + ++ + ++V ISS+ + G Y A KA + Sbjct: 100 DAVLNVNLKGVAYSIKPFIEGMYERKA--GSIVAISSISGERGNVGQTNYSATKAGVIGM 157 Query: 181 FQVLALEE--PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + LA E VR APG +DT+M RE D+R+ + + + + A Sbjct: 158 MKSLAREGARYGVRANAVAPGFIDTEMTLAIRE-----DIREKITKEIPFRRFGKPEEIA 212 Query: 239 QKLLSLLE 246 + LL Sbjct: 213 WAVAFLLS 220 >3OIC-A nrPDB Length = 258 Score = 153 bits (386), Expect = 7e-38, Method: Composition-based stats. Identities = 54/244 (22%), Positives = 112/244 (45%), Gaps = 18/244 (7%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 L+TG+SRG G+ A LA + ++++ AR+ +A + E+ E+ G++V+ Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAE--NGYNIVINYARSKKAALETAEEI--EKLGVKVLV 58 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 V A++G A ++++ + E + + +NNA V + ++L + T + Sbjct: 59 VKANVGQPAKIKEMFQQIDETFG----RLDVFVNNAA--SGVLRPVMEL-EETHWDWTMN 111 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 +N ++L K + G +V+ISSL +++ + + KAA + L + LA Sbjct: 112 INAKALLFCAQEAAKLMEKNGG--GHIVSISSLGSIRYLENYTTVGVSKAALEALTRYLA 169 Query: 186 LE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 +E + V + G +DTD + D+ + ++ G++V+ K + Sbjct: 170 VELSPKQIIVNAVSGGAIDTD---ALKHFPNREDLLEDARQNTPAGRMVEIKDMVDTVEF 226 Query: 244 LLEK 247 L+ Sbjct: 227 LVSS 230 >1K2W-A nrPDB Length = 256 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 53/248 (21%), Positives = 100/248 (40%), Gaps = 24/248 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TG++RG GR A G+ + ++ N EA R AE+G Sbjct: 3 LDGKTALITGSARGIGRAFAEAYVR---EGARVAIADINLEAARATAAEIGPAAC----- 54 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + D+ +A + + + L L R + +L+NNA V+++ + + + Sbjct: 55 AIALDVTDQASIDRCVAEL--LDRWGSID--ILVNNAALFD--LAPIVEITRES-YDRLF 107 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV- 183 A+N++ L + +V +A + G ++N++S + +YCA KAA L Q Sbjct: 108 AINVSGTLFMMQAVARAMI-AGGRGGKIINMASQAGRRGEALVGVYCATKAAVISLTQSA 166 Query: 184 -LALEEPNVRVLNYAPGPLDTDMQQLARETSVD------PDMRKGLQELKAKGKLVDCKV 236 L L + V APG +D + D + ++ + G++ + Sbjct: 167 GLNLIRHGINVNAIAPGVVDGEHWDGVDAKFADYENLPRGEKKRQVGAAVPFGRMGRAED 226 Query: 237 SAQKLLSL 244 + L Sbjct: 227 LTGMAIFL 234 >5OVJ-A nrPDB Length = 256 Score = 152 bits (383), Expect = 2e-37, Method: Composition-based stats. Identities = 47/241 (19%), Positives = 83/241 (34%), Gaps = 32/241 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG +RG G +A LA + G + ++ R A L V D Sbjct: 27 VLVTGGNRGIGLAIARRLA---ADGHKVAVTHRGSGAPDDL-------------FGVQCD 70 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + A + + + E P +L+ NAG D F+ + NLT Sbjct: 71 VTDSAAVDRAFKEVEEHQGP----VEVLVANAGISKDA---FLMRMTEERFEEVINTNLT 123 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 + ++ I S+ + A Y A KA + + ++ E Sbjct: 124 GAFRCAQRASRTMQRKRF--GRIIFIGSVSGMWGIGNQANYAAAKAGLIGMARSISRELA 181 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 + V APG +DT+M + D ++ G + ++ + A + L + Sbjct: 182 KAGVTANVVAPGYIDTEMTRAL-----DERIQAGALDFIPAKRVGTAEEVAGAVSFLASE 236 Query: 248 D 248 D Sbjct: 237 D 237 >4IIV-A nrPDB Length = 267 Score = 151 bits (382), Expect = 2e-37, Method: Composition-based stats. Identities = 49/242 (20%), Positives = 94/242 (38%), Gaps = 23/242 (9%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TGAS+G GR +A LA+ ++ V R+ ++ + A R++ D Sbjct: 29 VLVTGASKGIGRAIARQLAA--DGFNIGVHYHRDAAGAQETLNAIVANGGNGRLLSF--D 84 Query: 70 LGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 + +++L + + G+ ++NAG D + + D + NL Sbjct: 85 VANREQCREVLEHEIAQHGAWYGV-----VSNAGIARDAAFPALSNDD---WDAVIHTNL 136 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE- 187 S + + + ++ +SS+ + +G Y A KA + LA+E Sbjct: 137 DSFYNVIQPCIMPMIGAR-QGGRIITLSSVSGVMGNRGQVNYSAAKAGIIGATKALAIEL 195 Query: 188 -EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLE 246 + + V APG +DT M + ++ K + ++ + A L S L Sbjct: 196 AKRKITVNCIAPGLIDTGMIE------MEESALKEAMSMIPMKRMGQAEEVA-GLASYLM 248 Query: 247 KD 248 D Sbjct: 249 SD 250 >3VZS-A nrPDB Length = 257 Score = 151 bits (382), Expect = 3e-37, Method: Composition-based stats. Identities = 53/252 (21%), Positives = 90/252 (35%), Gaps = 23/252 (9%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + + +TG G G + LA V+ N + R+ + + G + Sbjct: 14 QRIAYVTGGMGGIGTAICQRLAK--DGFRVVAGCGPN--SPRREKWLEQQKALGFDFIAS 69 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 ++ + + + + + +LINNAG DV + Sbjct: 70 EGNVADWDSTKTAFDKV----KSEVGEVDVLINNAGITRDV---VFRKMTRADWDAVIDT 122 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 NLTS+ +T V+ D +VNISS+ + G Y KA LA Sbjct: 123 NLTSLFNVTKQVIDGMADRGW--GRIVNISSVNGQKGQFGQTNYSTAKAGLHGFTMALAQ 180 Query: 187 EEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSL 244 E V V +PG + TDM + R+ +D + +L + A + + Sbjct: 181 EVATKGVTVNTVSPGYIATDMVKAIRQDVLD-----KIVATIPVKRLGLPEEIA-SICAW 234 Query: 245 LEKDE--FKSGA 254 L +E F +GA Sbjct: 235 LSSEESGFSTGA 246 >2Q2Q-A nrPDB Length = 255 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 61/249 (24%), Positives = 95/249 (38%), Gaps = 24/249 (9%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L L+TG++ G G +A +LA G+ +VL+ + L R G++ Sbjct: 1 TLKGKTALVTGSTSGIGLGIAQVLAR---AGANIVLNG-FGDPAPALAE---IARHGVKA 53 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V PADL A ++ L G+ +L+NNAG L + Sbjct: 54 VHHPADLSDVAQIEALFALAER--EFGGVD--ILVNNAGIQHVAPVEQFPL---ESWDKI 106 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 ALNL+++ T L ++NI+S+ L G A Y A K L +V Sbjct: 107 IALNLSAVFHGTRLALPGMRARNW--GRIINIASVHGLVGSTGKAAYVAAKHGVVGLTKV 164 Query: 184 LALEEP--NVRVLNYAPGPLDTDMQQLARETSV----DPDMRKG--LQELKAKGKLVDCK 235 + LE NV PG + T + Q + DP + L E + V + Sbjct: 165 VGLETATSNVTCNAICPGWVLTPLVQKQIDDRAANGGDPLQAQHDLLAEKQPSLAFVTPE 224 Query: 236 VSAQKLLSL 244 + +L L Sbjct: 225 HLGELVLFL 233 >3ZV3-A nrPDB Length = 281 Score = 148 bits (374), Expect = 2e-36, Method: Composition-based stats. Identities = 60/250 (24%), Positives = 103/250 (41%), Gaps = 25/250 (10%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V L+TG + G GR L ++ G+ + + ++ E LR+LE G G+ V Sbjct: 2 KLTGEVALITGGASGLGRALVDRF---VAEGARVAVLDKSAERLRELEVAHGGNAVGV-V 57 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDS---TQV 120 V + + ++ L A ++ LI NAG D S DL + Sbjct: 58 GDVRSLQDQKRAAERCLAAFGKIDT--------LIPNAGI-WDYSTALADLPEDKIDAAF 108 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 ++ + +N+ + + L A S G +VV S P G LY A K A L Sbjct: 109 DDIFHVNVKGYIHAVKACLPALVSSRG---SVVFTISNAGFYPNGGGPLYTATKHAVVGL 165 Query: 181 FQVLALE-EPNVRVLNYAPGPLDTDMQ-----QLARETSVDPDMRKGLQELKAKGKLVDC 234 + +A E P+VRV APG ++TD++ L+ ++ + L+ + G++ Sbjct: 166 VRQMAFELAPHVRVNGVAPGGMNTDLRGPSSLGLSEQSISSVPLADMLKSVLPIGRMPAL 225 Query: 235 KVSAQKLLSL 244 + + Sbjct: 226 EEYTGAYVFF 235 >5VT6-A nrPDB Length = 269 Score = 147 bits (372), Expect = 4e-36, Method: Composition-based stats. Identities = 47/252 (18%), Positives = 88/252 (34%), Gaps = 20/252 (7%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 + V +TG G G ++ L +V + ++ + +G Sbjct: 24 AKRVAFVTGGMGGLGAAISRRLHDAGMAVAV----SHSERNDHVSTWLMHERDAGRDFKA 79 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 D+ ++ + + +LINNAG D + F+ ++ + Sbjct: 80 YAVDVADFESCERCAEKV----LADFGKVDVLINNAGITRDAT--FMKMTK-GDWDAVMR 132 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 +L +M +T + + +VNI S+ + G A Y + KA + LA Sbjct: 133 TDLDAMFNVTKQFIAGMVERRF--GRIVNIGSVNGSRGAFGQANYASAKAGIHGFTKTLA 190 Query: 186 LE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 LE + + V +PG L T M + + + + G+L A + Sbjct: 191 LETAKRGITVNTVSPGYLATAMVEAVPQ----DVLEAKILPQIPVGRLGRPDEVAALIAF 246 Query: 244 LLEKDE-FKSGA 254 L D F +GA Sbjct: 247 LCSDDAGFVTGA 258 >3OEC-A nrPDB Length = 317 Score = 147 bits (371), Expect = 5e-36, Method: Composition-based stats. Identities = 67/266 (25%), Positives = 103/266 (38%), Gaps = 32/266 (12%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSAR--NDEALRQLEAELGA-----E 57 L V +TGA+RG GRT A LA + + L + N + + EL E Sbjct: 44 LQGKVAFITGAARGQGRTHAVRLAQDGADIVAIDLCRQQPNLDYAQGSPEELKETVRLVE 103 Query: 58 RSGLRVVRVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSD 116 G R++ AD+ A LQ ++ AL E +L++N G V L+D Sbjct: 104 EQGRRIIARQADVRDLASLQAVVDEALAEFGHID-----ILVSNVGISN--QGEVVSLTD 156 Query: 117 STQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAA 176 Q ++ NL +VL + + G +V+ +SS L+ G + Y A K Sbjct: 157 -QQWSDILQTNLIGAWHACRAVLPSMIE-RGQGGSVIFVSSTVGLRGAPGQSHYAASKHG 214 Query: 177 RDMLFQVLALE--EPNVRVLNYAPGPLDTDMQ-----------QLARETSVDPDMRKGLQ 223 L LA E N+RV + PG ++T+M L T D Sbjct: 215 VQGLMLSLANEVGRHNIRVNSVNPGAVNTEMALNEKLLKMFLPHLENPTREDAAELFSQL 274 Query: 224 ELKAKGKLVDCKVSAQKLLSLLEKDE 249 L V+ + + ++ L DE Sbjct: 275 TLLPI-PWVEPEDVSNA-VAWLASDE 298 >5OJG-A nrPDB Length = 260 Score = 146 bits (369), Expect = 7e-36, Method: Composition-based stats. Identities = 52/245 (21%), Positives = 98/245 (40%), Gaps = 14/245 (5%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 V ++T A++G G +A L L G+ +V+ +RN + + + L + +V + Sbjct: 10 GKVAIVTAATKGIGLAIAERL---LDEGASVVIGSRNQKNVDEAIEYL-KNKGLTKVAGI 65 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 + + ++L+ K + +L+NN G +++SD + + + Sbjct: 66 AGHIASTDDQKKLVD----FTLQKFGKINILVNNHGI-NPAFGHILEVSDQV-WDKLFEV 119 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA- 185 N+ + +T V G ++ +S A + G A Y K L + LA Sbjct: 120 NVKAGFQMTKLVHPHIAKEGG--GAIIFNASYSAYKSPPGIAAYGVTKTTLVGLTRALAM 177 Query: 186 -LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSL 244 L + N+RV APG + T M Q+ + D + + A G+L A + L Sbjct: 178 GLAKDNIRVNGIAPGVIKTKMSQVLWDGGEDAEKELTDIQEIALGRLGVPDDCAGTVAYL 237 Query: 245 LEKDE 249 D Sbjct: 238 ASDDS 242 >5IZ4-A nrPDB Length = 271 Score = 146 bits (368), Expect = 9e-36, Method: Composition-based stats. Identities = 53/241 (21%), Positives = 95/241 (39%), Gaps = 9/241 (3%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 VC++TG++ G G A A ++ +A +EA +G + + A Sbjct: 16 VCVITGSASGIGAATALRFAQAGWSVAIGNFDDSTRDAASTVEALC--RDAGAQTLIFDA 73 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+G +A + + + R + + LIN AG+ + D D + + +NL Sbjct: 74 DVGKDADCRHAVDMVA--SRWQRID--ALINCAGTTRVIPHNAFDQIDDFEFERVYRVNL 129 Query: 129 TSMLCLTSSVLKAFPDSPGLNR--TVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 + +T + + +S R +VVN+SSL L Y A K A + L LA Sbjct: 130 IGLYQMTRAAVPLLRESASATRSTSVVNVSSLAGLNGTGSSIAYAASKGAVNTLTLSLAR 189 Query: 187 E-EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLL 245 P++RV APG +D + + + + + E ++ A+ L Sbjct: 190 NLAPHIRVNALAPGMVDDGLLLRVLDAAAYDGVLSRMTESAPLKRVSRPAEIAELAWFLT 249 Query: 246 E 246 Sbjct: 250 A 250 >4IS3-A nrPDB Length = 268 Score = 145 bits (367), Expect = 1e-35, Method: Composition-based stats. Identities = 48/245 (19%), Positives = 95/245 (38%), Gaps = 19/245 (7%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 + V ++TG +RG G A + + G+ + + E + A+L V+ Sbjct: 23 VQDKVTIITGGTRGIGFAAAKIF---IDNGAKVSIFGETQEEVDTALAQLKELYPEEEVL 79 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 DL + + + A+ ++ + G ++INNAG S + + Sbjct: 80 GFAPDLTSRDAV---MAAVGQVAQKYGR-LDVMINNAGIT---SNNVFSRVSEEEFKHIM 132 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N+T + + D+ ++N +S+ + Y A KA+ L L Sbjct: 133 DINVTGVFNGAWCAYQCMKDAK--KGVIINTASVTGIFGSLSGVGYPASKASVIGLTHGL 190 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 E N+RV+ APG ++TDM P++ +G + ++++ + A L Sbjct: 191 GREIIRKNIRVVGVAPGVVNTDMTN-----GNPPEIMEGYLKALPMKRMLEPEEIANVYL 245 Query: 243 SLLEK 247 L Sbjct: 246 FLASD 250 >1YXM-A nrPDB Length = 303 Score = 144 bits (363), Expect = 3e-35, Method: Composition-based stats. Identities = 54/261 (20%), Positives = 98/261 (37%), Gaps = 20/261 (7%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG-- 60 G L V ++TG + G G+ + L L GS +V+++R E L+ EL A Sbjct: 14 GLLQGQVAIVTGGATGIGKAIVKELLEL---GSNVVIASRKLERLKSAADELQANLPPTK 70 Query: 61 -LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119 RV+ + ++ E + L+ + + + L+NN G + S Sbjct: 71 QARVIPIQCNIRNEEEVNNLVKSTLDTFG----KINFLVNNGGGQFLSPAEHIS---SKG 123 Query: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 + NLT + +V ++ ++VNI + F A +A Sbjct: 124 WHAVLETNLTGTFYMCKAVYSSWMKE--HGGSIVNII-VPTKAGFPLAVHSGAARAGVYN 180 Query: 180 LFQVLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVS 237 L + LALE +R+ APG + + + S +G + ++ + Sbjct: 181 LTKSLALEWACSGIRINCVAPGVIYSQ-TAVENYGSWGQSFFEGSFQKIPAKRIGVPEEV 239 Query: 238 AQKLLSLLE-KDEFKSGAHVD 257 + + LL F +G VD Sbjct: 240 SSVVCFLLSPAASFITGQSVD 260 >1NFF-A nrPDB Length = 260 Score = 143 bits (360), Expect = 8e-35, Method: Composition-based stats. Identities = 58/258 (22%), Positives = 98/258 (37%), Gaps = 32/258 (12%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M G L V L++G +RG G A + ++++ G+ +V DE + + A Sbjct: 1 MSGRLTGKVALVSGGARGMG---ASHVRAMVAEGAKVVFGDILDEEGKAMAA-----ELA 52 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 V D+ A + + +L+NNAG L + L+ + Sbjct: 53 DAARYVHLDVTQPAQWKAAVDTAVTAFG----GLHVLVNNAGILNIGTIEDYALT---EW 105 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +NLT + +V+K ++ +++NISS+ L Y A K A L Sbjct: 106 QRILDVNLTGVFLGIRAVVKPMKEAGR--GSIINISSIEGLAGTVACHGYTATKFAVRGL 163 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + ALE +RV + PG + T M E A G+ + + Sbjct: 164 TKSTALELGPSGIRVNSIHPGLVKTPMTDWVPEDIF----------QTALGRAAEPVEVS 213 Query: 239 QKLLSLLEKDE--FKSGA 254 L+ L DE + +GA Sbjct: 214 N-LVVYLASDESSYSTGA 230 >1UZM-A nrPDB Length = 247 Score = 143 bits (360), Expect = 8e-35, Method: Composition-based stats. Identities = 54/248 (21%), Positives = 93/248 (37%), Gaps = 33/248 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG +RG G +A LA + G + ++ R A + L V D Sbjct: 18 VLVTGGNRGIGLAIAQRLA---ADGHKVAVTHRGSGAPKGL-------------FGVEVD 61 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + + + A+ E P +L++NAG D F+ + NLT Sbjct: 62 VTDSDAVDRAFTAVEEHQGP----VEVLVSNAGLSADA---FLMRMTEEKFEKVINANLT 114 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 + ++ + ++ I S+ L A Y A KA + + +A E Sbjct: 115 GAFRVAQRASRSMQRNKF--GRMIFIGSVSGLWGIGNQANYAASKAGVIGMARSIARELS 172 Query: 188 EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 + NV APG +DTDM + D +++G + ++ A + L + Sbjct: 173 KANVTANVVAPGYIDTDMTRAL-----DERIQQGALQFIPAKRVGTPAEVAGVVSFLASE 227 Query: 248 D-EFKSGA 254 D + SGA Sbjct: 228 DASYISGA 235 >3V2H-A nrPDB Length = 281 Score = 143 bits (360), Expect = 9e-35, Method: Composition-based stats. Identities = 52/259 (20%), Positives = 100/259 (38%), Gaps = 22/259 (8%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 ++TG++ G G +A LA + ++++ + +R + E+ SG V+ P Sbjct: 26 KTAVITGSTSGIGLAIARTLAK--AGANIVLNGFGAPDEIRTVTDEVAGLSSG-TVLHHP 82 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 AD+ + + ++ + R G +L+NNAG + Q + A+N Sbjct: 83 ADMTKPSEIADMMAMVA--DRFGGAD--ILVNNAGVQFVEKIEDFPV---EQWDRIIAVN 135 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 L+S + ++NI+S L + Y A K L + +ALE Sbjct: 136 LSSSFHTIRGAIPPMKKKGW--GRIINIASAHGLVASPFKSAYVAAKHGIMGLTKTVALE 193 Query: 188 --EPNVRVLNYAPGPLDTDMQQLARETSV-------DPDMRKGLQELKAKGKLVDCKVSA 238 E V V + PG + T + + + + + + + + K + + A Sbjct: 194 VAESGVTVNSICPGYVLTPLVEKQIPDQARTRGITEEQVINEVMLKGQPTKKFITVEQVA 253 Query: 239 QKLLSLLEKDEFK-SGAHV 256 L L D + +G HV Sbjct: 254 SLALYLAGDDAAQITGTHV 272 >2X9N-A nrPDB Length = 288 Score = 142 bits (358), Expect = 1e-34, Method: Composition-based stats. Identities = 62/257 (24%), Positives = 96/257 (37%), Gaps = 36/257 (14%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARN-DEALRQLEAELGAERSGLRVVRVPA 68 ++TGA++ GR +A L G +V+ N EA L EL ERS V A Sbjct: 26 AVVTGAAKRIGRAIA---VKLHQTGYRVVIHYHNSAEAAVSLADELNKERSN-TAVVCQA 81 Query: 69 DLGA----EAGLQQLLGA-LRELPRPKGLQRLLLINNAG-------SLGDVSKGFVDLSD 116 DL A ++++ + R R +L+NNA GD + Sbjct: 82 DLTNSNVLPASCEEIINSCFRAFGRCD-----VLVNNASAFYPTPLVQGDHEDNSNGKTV 136 Query: 117 STQVNNYWALNLTSMLCLTSSVLK----AFPDSPGLNRTVVNISSLCALQPFKGWALYCA 172 TQV N + LT S + P+ N ++VN+ QP ++LY Sbjct: 137 ETQVAELIGTNAIAPFLLTMSFAQRQKGTNPNCTSSNLSIVNLCDAMVDQPCMAFSLYNM 196 Query: 173 GKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGK 230 GK A L Q ALE +RV APG ++ + + + G+ Sbjct: 197 GKHALVGLTQSAALELAPYGIRVNGVAPGV-------SLLPVAMGEEEKDKWRRKVPLGR 249 Query: 231 L-VDCKVSAQKLLSLLE 246 + A ++ L+ Sbjct: 250 REASAEQIADAVIFLVS 266 >5YSS-A nrPDB Length = 256 Score = 141 bits (356), Expect = 2e-34, Method: Composition-based stats. Identities = 56/252 (22%), Positives = 95/252 (37%), Gaps = 26/252 (10%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSA-RNDEALRQLEAELGAERSGLRV 63 L L+TG++ G G +A +LA G+ L+L+ + +A + A + G Sbjct: 3 LTGKTALVTGSTSGIGLGIAQVLAQ---AGATLILNGFGDVDAAKDAVA-----QYGKTP 54 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 ADL EA + ++ G+ +LINNAG + + N Sbjct: 55 GYHGADLSDEAQIADMMRYAE--SEFGGVD--ILINNAGIQHVSPIETFPV---DKWNAI 107 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 A+NL+S+ T L ++NI+S+ L K + Y A K L + Sbjct: 108 IAINLSSVFHTTRLALPGMRARNW--GRIINIASVHGLVASKEKSAYVAAKHGVVGLTKT 165 Query: 184 LALEEPN--VRVLNYAPGPLDTDMQQLARETS----VDPDMRKG--LQELKAKGKLVDCK 235 +ALE + PG + T + Q + +P+ + L E + + V + Sbjct: 166 IALETAQTEITCNALCPGWVLTPLVQQQIDKRIAEGAEPEAARDALLAEKQPSREFVTPE 225 Query: 236 VSAQKLLSLLEK 247 L L Sbjct: 226 QLGNLALFLCSD 237 >3W8F-A nrPDB Length = 260 Score = 140 bits (354), Expect = 4e-34, Method: Composition-based stats. Identities = 49/249 (19%), Positives = 90/249 (36%), Gaps = 21/249 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TG++ G G +A LA G+ +V++ + E + G++ Sbjct: 2 LKGKKAVVTGSTSGIGLAMATELAK---AGADVVINGFGQPEDIERERSTLESKFGVKAY 58 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + ADL + + E +L+NNAG + + N Sbjct: 59 YLNADLSDAQATRDFIAKAAEALG----GLDILVNNAGIQHTAPIEEFPV---DKWNAII 111 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 ALNL+++ T++ L ++NI+S L + Y A K L +V Sbjct: 112 ALNLSAVFHGTAAALPIMQKQGW--GRIINIASAHGLVASVNKSAYVAAKHGVVGLTKVT 169 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETS-------VDPDMRKGLQELKAKGKLVDCK 235 ALE + PG + T + + E ++ R+ L E + + V + Sbjct: 170 ALENAGKGITCNAICPGWVRTPLVEKQIEAISQQKGIDIEAAARELLAEKQPSLQFVTPE 229 Query: 236 VSAQKLLSL 244 + L Sbjct: 230 QLGGAAVFL 238 >5U9P-A nrPDB Length = 265 Score = 140 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 49/242 (20%), Positives = 88/242 (36%), Gaps = 19/242 (7%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TG+ RG G TLA LA G+ +V++ RN+E L E G Sbjct: 18 LDGRRALITGSGRGIGLTLARGLA---EAGAAIVINDRNEEKAATLARRFRDE--GFAAD 72 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 D+ A ++ + +L+NNAG +D + + Sbjct: 73 HAVFDVAEHAQVRAAIDEFEARVGA----IDILVNNAGIQRRAP---LDAFEPDDWHALM 125 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +NL + + +V + + ++NI S+ + A Y A K A ML + + Sbjct: 126 RVNLDGVFNVAQAVARHMIARG--HGKIINICSVQSELARPTIAPYAATKGAVRMLTKGM 183 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 + ++ APG +T++ + + D L + G+ + Sbjct: 184 CADWARYGIQANGLAPGYFETELNRALVD---DAAFSDWLCKRTPAGRWGQVDELCGAAI 240 Query: 243 SL 244 L Sbjct: 241 FL 242 >4AVY-A nrPDB Length = 242 Score = 139 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 51/241 (21%), Positives = 85/241 (35%), Gaps = 32/241 (13%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 L+TG S G G +A A L G+ +V + + + R+ R Sbjct: 10 AGQQVLVTGGSSGIGAAIAMQFAEL---GAEVVALGLDADGVHA--------PRHPRIRR 58 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 D+ LQ+L AL L +L+NNAG D + D Sbjct: 59 EELDITDSQRLQRLFEALPRLD--------VLVNNAGISRDREEY-----DLATFERVLR 105 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 LNL++ + + +++NI+S+ + Y A K A L + LA Sbjct: 106 LNLSAAMLASQLARPLLAQR---GGSILNIASMYSTFGSADRPAYSASKGAIVQLTRSLA 162 Query: 186 LEEPN--VRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 E +RV APG +DT + + D + + + + + + A Sbjct: 163 CEYAAERIRVNAIAPGWIDTPLGAGLK---ADVEATRRIMQRTPLARWGEAPEVASAAAF 219 Query: 244 L 244 L Sbjct: 220 L 220 >4Z9Y-A nrPDB Length = 253 Score = 139 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 51/246 (20%), Positives = 99/246 (40%), Gaps = 22/246 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V L+TG G G+ +A LA + ++ ++ + + L G R + Sbjct: 8 LQGKVALITGCDTGLGQGMAIGLAQ--AGCDIVGVNIVEPKDTIEKVTAL-----GRRFL 60 Query: 65 RVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + AD+ +G +L+ A+ E +L+NNAG + ++ Sbjct: 61 SLTADMSNVSGHAELVEKAVAEFGHVD-----ILVNNAGIIRREDAIEFS---EKNWDDV 112 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 LN+ S+ ++ +V + F G ++NI+S+ + Q Y A K+A + ++ Sbjct: 113 MNLNIKSVFFMSQTVARQFIK-QGKGGKIINIASMLSFQGGIRVPSYTASKSAVMGVTRL 171 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 +A E + + V APG + T+ Q R D + K + + G+ + Sbjct: 172 MANEWAKHGINVNAIAPGYMATNNTQQLR---ADEERSKEILDRIPAGRWGLPQDLMGPS 228 Query: 242 LSLLEK 247 + L Sbjct: 229 VFLASS 234 >1X1T-A nrPDB Length = 260 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 54/253 (21%), Positives = 105/253 (41%), Gaps = 23/253 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V ++TG++ G G +A LA+ +++ + + ++ A L A+ G++V+ Sbjct: 2 LKGKVAVVTGSTSGIGLGIATALAA--QGADIVLNGFGDAAEIEKVRAGLAAQH-GVKVL 58 Query: 65 RVPADLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 ADL ++ L+ A+R++ R +L+NNAG ++ + + + Sbjct: 59 YDGADLSKGEAVRGLVDNAVRQMGRID-----ILVNNAGIQH---TALIEDFPTEKWDAI 110 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 ALNL+++ T++ L ++NI+S L + Y A K +V Sbjct: 111 LALNLSAVFHGTAAALPHMKKQGF--GRIINIASAHGLVASANKSAYVAAKHGVVGFTKV 168 Query: 184 LALEEP--NVRVLNYAPGPLDTDMQQL-----ARETSVDPDM--RKGLQELKAKGKLVDC 234 ALE + PG + T + + A + VD + R+ L E + + V Sbjct: 169 TALETAGQGITANAICPGWVRTPLVEKQISALAEKNGVDQETAARELLSEKQPSLQFVTP 228 Query: 235 KVSAQKLLSLLEK 247 + + L Sbjct: 229 EQLGGTAVFLASD 241 >3RWB-A nrPDB Length = 247 Score = 138 bits (348), Expect = 2e-33, Method: Composition-based stats. Identities = 52/246 (21%), Positives = 96/246 (39%), Gaps = 22/246 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TGA++G G+ +A LA + G+ +++S N E + A +G + Sbjct: 4 LAGKTALVTGAAQGIGKAIAARLA---ADGATVIVSDINAEGAKAAAASIGK-----KAR 55 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + AD+ ++ L ++ L +L+NNA + V+ VDL Sbjct: 56 AIAADISDPGSVKALFAEIQALTG----GIDILVNNASIVPFVAWDDVDL---DHWRKII 108 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +NLT +T + + G V++I+S A Y A K + L Sbjct: 109 DVNLTGTFIVTRAGTDQM-RAAGKAGRVISIASNTFFAGTPNMAAYVAAKGGVIGFTRAL 167 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E + N+ PG +++D + + + ++ L+A + A + Sbjct: 168 ATELGKYNITANAVTPGLIESDGVKASPHN----EAFGFVEMLQAMKGKGQPEHIADVVS 223 Query: 243 SLLEKD 248 L D Sbjct: 224 FLASDD 229 >2HSD-A nrPDB Length = 253 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 58/256 (22%), Positives = 98/256 (38%), Gaps = 27/256 (10%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TG +RG G A ++ G+ +VL+ DE EL G Sbjct: 3 LSGKTVIITGGARGLG---AEAARQAVAAGARVVLADVLDEEGAATAREL-----GDAAR 54 Query: 65 RVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 D+ E Q+++ A E G L+NNAG + F++ + Sbjct: 55 YQHLDVTIEEDWQRVVAYAREEFGSVDG-----LVNNAGI---STGMFLETESVERFRKV 106 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NLT + +V+ A D+ G ++VNISS L + Y A K L ++ Sbjct: 107 VEINLTGVFIGMKTVIPAMKDAGG--GSIVNISSAAGLMGLALTSSYGASKWGVRGLSKL 164 Query: 184 LALEE--PNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 A+E +RV + PG T M + + G++ + A + Sbjct: 165 AAVELGTDRIRVNSVHPGMTYTPMTAETGIRQGEGNYPNT-----PMGRVGEPGEIAGAV 219 Query: 242 LSLLEK-DEFKSGAHV 256 + LL + +GA + Sbjct: 220 VKLLSDTSSYVTGAEL 235 >5JS6-A nrPDB Length = 274 Score = 137 bits (344), Expect = 5e-33, Method: Composition-based stats. Identities = 52/230 (22%), Positives = 89/230 (38%), Gaps = 22/230 (9%) Query: 29 SLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLL-GALRELP 87 + ++ G+ +V+ +++ R LE EL V + D+ E ++ L+ +R Sbjct: 30 AFVNSGARVVICDKDESGGRALEQELPG------AVFILCDVTQEDDVKTLVSETIRRFG 83 Query: 88 RPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPG 147 R ++NNAG + + + + LNL LT L S G Sbjct: 84 RLD-----CVVNNAGHHPPPQRP--EETSAQGFRQLLELNLLGTYTLTKLALPYLRKSQG 136 Query: 148 LNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDM 205 V+NISSL Y A K A + + LAL+ VRV +PG + T + Sbjct: 137 ---NVINISSLVGAIGQAQAVPYVATKGAVTAMTKALALDESPYGVRVNCISPGNIWTPL 193 Query: 206 QQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKSG 253 + DP +R+G+ G++ + L + F +G Sbjct: 194 WEELAALMPDPRATIREGMLAQ-PLGRMGQPAEVGAAAVFLASEANFCTG 242 >1BDB-A nrPDB Length = 277 Score = 135 bits (340), Expect = 2e-32, Method: Composition-based stats. Identities = 56/250 (22%), Positives = 98/250 (39%), Gaps = 25/250 (10%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L L+TG + G GR L ++ G+ + + ++ E L +LE + G V Sbjct: 2 KLKGEAVLITGGASGLGRALVDRF---VAEGAKVAVLDKSAERLAELETDHGDN-----V 53 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDS---TQV 120 + + D+ + +Q A R + R + LI NAG D S VDL + Sbjct: 54 LGIVGDVRSLEDQKQ--AASRCVARFGKID--TLIPNAGI-WDYSTALVDLPEESLDAAF 108 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + + +N+ + + L A S G V+ S P G LY A K A L Sbjct: 109 DEVFHINVKGYIHAVKACLPALVASRG---NVIFTISNAGFYPNGGGPLYTAAKHAIVGL 165 Query: 181 FQVLALE-EPNVRVLNYAPGPLDTDMQ-----QLARETSVDPDMRKGLQELKAKGKLVDC 234 + LA E P VRV G +++D++ + + + L+ + G++ + Sbjct: 166 VRELAFELAPYVRVNGVGSGGINSDLRGPSSLGMGSKAISTVPLADMLKSVLPIGRMPEV 225 Query: 235 KVSAQKLLSL 244 + + Sbjct: 226 EEYTGAYVFF 235 >3UF0-A nrPDB Length = 273 Score = 135 bits (339), Expect = 2e-32, Method: Composition-based stats. Identities = 56/246 (22%), Positives = 88/246 (35%), Gaps = 21/246 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L ++TGA G GR +A A G+ ++ R + ++++ E+ G Sbjct: 28 SLAGRTAVVTGAGSGIGRAIAHGYAR---AGAHVLAWGRT-DGVKEVADEIA--DGGGSA 81 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V ADL G + L R +L+NNAG + V L +V Sbjct: 82 EAVVADLADLEGAANVAEELAATRRVD-----VLVNNAGIIARAPAEEVSLGRWREV--- 133 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NL + L+ S A +V I+S+ + Q + A Y A K A L + Sbjct: 134 LTVNLDAAWVLSRSFGTAMLAHGS--GRIVTIASMLSFQGGRNVAAYAASKHAVVGLTRA 191 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA E V V APG + T R D + + G+ + Sbjct: 192 LASEWAGRGVGVNALAPGYVVTANTAALR---ADDERAAEITARIPAGRWATPEDMVGPA 248 Query: 242 LSLLEK 247 + L Sbjct: 249 VFLASD 254 >4TRR-A nrPDB Length = 269 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 46/249 (18%), Positives = 92/249 (36%), Gaps = 22/249 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TGA+ G G+ +A LA + + ++ N + + E+ ++G + + Sbjct: 12 LNGKTAVVTGAASGIGKEIALELAKAGAAVA---IADLNQDGANAVADEI--NKAGGKAI 66 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 V D+ E + + + E +L++NAG +D ++ Sbjct: 67 GVAMDVTNEEAVNTGIDKVAEAFGS----VDILVSNAGIQIVNPIENYSFADWKKMQ--- 119 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 A+++ T + LK V+ + S+ + + + Y K L +VL Sbjct: 120 AIHVDGAFLTTKAALKHMYKDDR-GGVVIYMGSVHSHEASPLKSAYVTAKHGLLGLARVL 178 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSV-------DPDMRKGLQELKAKGKLVDCK 235 A E + NVR PG + T + + ++K + G + Sbjct: 179 AKEGAKHNVRSHVVCPGFVRTPLVDKQIPEQAKELGISEEEVIKKVMLGNTVDGVFTTVQ 238 Query: 236 VSAQKLLSL 244 AQ +L L Sbjct: 239 DVAQTVLFL 247 >4E6P-A nrPDB Length = 259 Score = 134 bits (338), Expect = 3e-32, Method: Composition-based stats. Identities = 54/257 (21%), Positives = 98/257 (38%), Gaps = 24/257 (9%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M L L+TG++RG GR A G+ + ++ + E RQ AE+ G Sbjct: 2 MMKRLEGKSALITGSARGIGRAFAEAYVR---EGATVAIADIDIERARQAAAEI-----G 53 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 V D+ + + + A E GL +L+NNA V+++ + Sbjct: 54 PAAYAVQMDVTRQDSIDAAIAATVE--HAGGLD--ILVNNAALFD--LAPIVEITRES-Y 106 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +A+N+ L + + + G ++N++S + A+YCA KAA L Sbjct: 107 EKLFAINVAGTLFTLQAAARQMI-AQGRGGKIINMASQAGRRGEALVAIYCATKAAVISL 165 Query: 181 FQVLALE--EPNVRVLNYAPGPLD------TDMQQLARETSVDPDMRKGLQELKAKGKLV 232 Q L+ + + V APG +D D E + ++ + E G++ Sbjct: 166 TQSAGLDLIKHRINVNAIAPGVVDGEHWDGVDALFARYENRPRGEKKRLVGEAVPFGRMG 225 Query: 233 DCKVSAQKLLSLLEKDE 249 + + L + Sbjct: 226 TAEDLTGMAIFLASAES 242 >4HP8-A nrPDB Length = 247 Score = 134 bits (337), Expect = 4e-32, Method: Composition-based stats. Identities = 52/243 (21%), Positives = 88/243 (36%), Gaps = 25/243 (10%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L L+TGA+ G G+ +A LA + G+ +V +AR A + + + Sbjct: 6 SLEGRKALVTGANTGLGQAIAVGLA---AAGAEVVCAARR--APDETLDIIAKDGGNASA 60 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + + D + +L+NNAG + + Sbjct: 61 LLI--DFADPLAAKDSFTDA---------GFDILVNNAGIIRRADSVEFS---ELDWDEV 106 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NL ++ T + K G + VVNI+SL + Q Y A K L ++ Sbjct: 107 MDVNLKALFFTTQAFAKELLAK-GRSGKVVNIASLLSFQGGIRVPSYTAAKHGVAGLTKL 165 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA E + V APG ++T+ + R D K + E G+ + A Sbjct: 166 LANEWAAKGINVNAIAPGYIETNNTEALR---ADAARNKAILERIPAGRWGHSEDIAGAA 222 Query: 242 LSL 244 + L Sbjct: 223 VFL 225 >1AHH-A nrPDB Length = 255 Score = 134 bits (336), Expect = 6e-32, Method: Composition-based stats. Identities = 59/243 (24%), Positives = 104/243 (42%), Gaps = 23/243 (9%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TGA G G+ +A A+ G+ +V+S N +A + E+ ++ G + Sbjct: 9 LDGKCAIITGAGAGIGKEIAITFAT---AGASVVVSDINADAANHVVDEI--QQLGGQAF 63 Query: 65 RVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 D+ +E L L A+ +L + +L+NNAG G K F Sbjct: 64 ACRCDITSEQELSALADFAISKLGKVD-----ILVNNAG--GGGPKPF--DMPMADFRRA 114 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 + LN+ S L+ V + G ++ I+S+ A Y + KAA L + Sbjct: 115 YELNVFSFFHLSQLVAPEMEKNGG--GVILTITSMAAENKNINMTSYASSKAAASHLVRN 172 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 +A + E N+RV APG + TD A ++ + P++ + + + +L + A Sbjct: 173 MAFDLGEKNIRVNGIAPGAILTD----ALKSVITPEIEQKMLQHTPIRRLGQPQDIANAA 228 Query: 242 LSL 244 L L Sbjct: 229 LFL 231 >2EW8-A nrPDB Length = 249 Score = 132 bits (333), Expect = 1e-31, Method: Composition-based stats. Identities = 42/251 (16%), Positives = 91/251 (36%), Gaps = 22/251 (8%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M L + ++TG + G GR +A A + ++ + + EAE G Sbjct: 1 MTQRLKDKLAVITGGANGIGRAIAERFAVEGADIAI-------ADLVPAPEAEAAIRNLG 53 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 RV+ V D+ ++ + + +L+NNAG + + Q Sbjct: 54 RRVLTVKCDVSQPGDVEAFGKQVISTFG----RCDILVNNAGIYPLIPFDELT---FEQW 106 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + +N+ S + + + + ++N++S + + Y + KAA Sbjct: 107 KKTFEINVDSGFLMAKAFVPGMKRNGW--GRIINLTSTTYWLKIEAYTHYISTKAANIGF 164 Query: 181 FQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + LA L + + V AP + T + + +++ + LQ + + + Sbjct: 165 TRALASDLGKDGITVNAIAPSLVRTATTEASALSAMFDVLPNMLQA-IPR---LQVPLDL 220 Query: 239 QKLLSLLEKDE 249 + L D+ Sbjct: 221 TGAAAFLASDD 231 >1SNY-A nrPDB Length = 267 Score = 132 bits (332), Expect = 2e-31, Method: Composition-based stats. Identities = 53/207 (25%), Positives = 91/207 (43%), Gaps = 17/207 (8%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG +RG G L L +L P L + RN E ++LE +L S + ++ + DL Sbjct: 25 LITGCNRGLGLGLVKALLNLPQPPQHLFTTCRNREQAKELE-DLAKNHSNIHILEI--DL 81 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFV----DLSDSTQVNNYWAL 126 +L+ + + + +GL +L NNAG ++ +L D+ Q N + Sbjct: 82 RNFDAYDKLVADIEGVTKDQGLN--VLFNNAGIAPKSARITAVRSQELLDTLQTNTVVPI 139 Query: 127 NL-TSMLCLTSSVLKAFPDSPGLNRT--VVNISSLCA-LQPF--KGWALYCAGKAARDML 180 L + L L KA P ++N+SS+ +Q G Y K+A + Sbjct: 140 MLAKACLPLLKKAAKANESQPMGVGRAAIINMSSILGSIQGNTDGGMYAYRTSKSALNAA 199 Query: 181 FQVLALEEPNVRVLNY--APGPLDTDM 205 + L+++ R++ PG + TDM Sbjct: 200 TKSLSVDLYPQRIMCVSLHPGWVKTDM 226 >3WYE-A nrPDB Length = 256 Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats. Identities = 53/248 (21%), Positives = 102/248 (41%), Gaps = 20/248 (8%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + V L+TGA +G G+ +A L G + ++ ND + + +E+ ++G V V Sbjct: 2 KKVALVTGAGQGIGKAIALRLVK---DGFAVAIADYNDATAKAVASEI--NQAGGHAVAV 56 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ Q+ A+ + + G +++NNAG K ++++ + +++ Sbjct: 57 KVDVSDR---DQVFAAVEQARKTLG-GFDVIVNNAGIAQ--IKPLLEVT-EEDLKQIYSV 109 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 N+ S+ + ++AF G ++N +S+ A+Q F + Y K A L Q A Sbjct: 110 NVFSVFFGIQAAVEAF-KKEGHGGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQTAAR 168 Query: 187 EEP--NVRVLNYAPGPLDTDM---QQLARETSVDPDMRKGLQELKAKGKLVDCKVS--AQ 239 + + V Y PG + T M + + +E + L V Sbjct: 169 DLAPLGITVNGYCPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVA 228 Query: 240 KLLSLLEK 247 L+S L Sbjct: 229 GLVSFLAS 236 >3DWF-A nrPDB Length = 276 Score = 130 bits (326), Expect = 8e-31, Method: Composition-based stats. Identities = 50/204 (24%), Positives = 85/204 (41%), Gaps = 18/204 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TGAS+G GR +A LA + G+ +V++AR+ EAL+++ A E Sbjct: 9 LQGKKVIVTGASKGIGREIAYHLAKM---GAHVVVTARSKEALQKVVARC-LELGAASAH 64 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + + ++ + L GL L+L + L + F D V Sbjct: 65 YIAGSMEDMTFAEEFVAEAGNL--MGGLDMLILNH---VLYNRLTFFHGEID--NVRKSM 117 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N S + L+ + + S G ++ +SS+ + A Y A K A D F L Sbjct: 118 EVNFHSFVVLSVAAMPMLMQSQG---SIAVVSSVAGKITYPLIAPYSASKFALDGFFSTL 174 Query: 185 ALE----EPNVRVLNYAPGPLDTD 204 E + NV + G +DT+ Sbjct: 175 RSEFLVNKVNVSITLCILGLIDTE 198 >3T7C-A nrPDB Length = 299 Score = 129 bits (325), Expect = 1e-30, Method: Composition-based stats. Identities = 49/269 (18%), Positives = 91/269 (33%), Gaps = 30/269 (11%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALR-------QLEAE 53 M G + V +TGA+RG GR+ A LA + + + + + ++ L Sbjct: 22 MAGKVEGKVAFITGAARGQGRSHAITLAREGAD-IIAIDVCKQLDGVKLPMSTPDDLAET 80 Query: 54 LGA-ERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFV 112 + E G R++ D+ +Q + + + L +++ NA + Sbjct: 81 VRQVEALGRRIIASQVDVRDFDAMQAAVD--DGVTQLGRLD--IVLANAALA--SEGTRL 134 Query: 113 DLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCA 172 + D + +NL + ++V SS+ L+ + Y A Sbjct: 135 NRMDPKTWRDMIDVNLNGAWITARVAIPHIMAGKR-GGSIVFTSSIGGLRGAENIGNYIA 193 Query: 173 GKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQ-----------QLARETSVDPDMR 219 K L + +ALE N+RV P + T M L T D + Sbjct: 194 SKHGLHGLMRTMALELGPRNIRVNIVCPSSVATPMLLNEPTYRMFRPDLENPTVEDFQVA 253 Query: 220 KGLQELKAKGKLVDCKVSAQKLLSLLEKD 248 + V+ + +L L+ D Sbjct: 254 SRQMHVLPIPY-VEPADISNAILFLVSDD 281 >1DOH-A nrPDB Length = 283 Score = 129 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 42/205 (20%), Positives = 81/205 (39%), Gaps = 18/205 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V L+TGA RG GR +A L V+V A + E+ ++ A + G Sbjct: 26 SLEGKVALVTGAGRGIGREMAMELGR--RGCKVIVNYANSTESAEEVVAAIKKN--GSDA 81 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V A++G + ++ ++ + ++ +N+G VS G V + + Sbjct: 82 ACVKANVGVVEDIVRMFEEAVKIFG----KLDIVCSNSGV---VSFGHVKDVTPEEFDRV 134 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCA-LQPFKGWALYCAGKAARDMLFQ 182 + +N + K + ++ + S+ + A+Y K A + + Sbjct: 135 FTINTRGQFFVAREAYKHLE----IGGRLILMGSITGQAKAVPKHAVYSGSKGAIETFAR 190 Query: 183 VLALEEP--NVRVLNYAPGPLDTDM 205 +A++ + V APG + TDM Sbjct: 191 CMAIDMADKKITVNVVAPGGIKTDM 215 >4DA9-A nrPDB Length = 280 Score = 127 bits (318), Expect = 6e-30, Method: Composition-based stats. Identities = 63/243 (25%), Positives = 97/243 (39%), Gaps = 18/243 (7%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 R V ++TG RG G +A LA+ S + + + E + + AEL G RV+ Sbjct: 28 ARPVAIVTGGRRGIGLGIARALAA--SGFDIAITGIGDAEGVAPVIAELSG--LGARVIF 83 Query: 66 VPADLGAEAGLQQLLGAL-RELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + ADL + Q + A+ E R L+NNAG V F+DL + Sbjct: 84 LRADLADLSSHQATVDAVVAEFGRID-----CLVNNAGIASIVRDDFLDLKPE-NFDTIV 137 Query: 125 ALNLTSMLCLTSSVLKAFPDSP-GLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +NL + T +VLKA S +R+++NI+S+ A+ YC KA Q Sbjct: 138 GVNLRGTVFFTQAVLKAMLASDARASRSIINITSVSAVMTSPERLDYCMSKAGLAAFSQG 197 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LAL E + V PG + +DM L + + + + Sbjct: 198 LALRLAETGIAVFEVRPGIIRSDMTAAVSGKYDGLIES----GLVPMRRWGEPEDIGNIV 253 Query: 242 LSL 244 L Sbjct: 254 AGL 256 >3UVE-A nrPDB Length = 286 Score = 126 bits (316), Expect = 1e-29, Method: Composition-based stats. Identities = 47/275 (17%), Positives = 95/275 (34%), Gaps = 37/275 (13%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLS-------------ARNDEAL 47 M G + V +TGA+RG GR+ A LA + + + A E L Sbjct: 5 MTGRVEGKVAFVTGAARGQGRSHAVRLAQEGADIIAVDICKPIRAGVVDTAIPASTPEDL 64 Query: 48 RQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGA-LRELPRPKGLQRLLLINNAGSLGD 106 + + + R+V D+ L+ + + + +L R +++ NAG Sbjct: 65 AETADLV--KGHNRRIVTAEVDVRDYDALKAAVDSGVEQLGRLD-----IIVANAGI--G 115 Query: 107 VSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKG 166 +D + +NL + + + + G +++ SS+ L+ + Sbjct: 116 NGGDTLDKTSEEDWTEMIDINLAGVWKTVKAGVPHMI-AGGRGGSIILTSSVGGLKAYPH 174 Query: 167 WALYCAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTDM--QQLARETSVDPDMRKGL 222 Y A K L + +E + +RV + P + T M + + G Sbjct: 175 TGHYVAAKHGVVGLMRAFGVELGQHMIRVNSVHPTHVKTPMLHNEGTFKMFRPDLENPGP 234 Query: 223 QELKAKGKL--------VDCKVSAQKLLSLLEKDE 249 ++ ++ V+ + +L DE Sbjct: 235 DDMAPICQMFHTLPIPWVEPIDISNAVLFF-ASDE 268 >3UN1-A nrPDB Length = 260 Score = 124 bits (311), Expect = 5e-29, Method: Composition-based stats. Identities = 52/259 (20%), Positives = 95/259 (36%), Gaps = 40/259 (15%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 + V ++TGAS+G G L +V ++R+ + + Sbjct: 27 QQKVVVITGASQGIGAGLVRAY---RDRNYRVVATSRS-----------IKPSADPDIHT 72 Query: 66 VPADLGAEAGLQQLL-GALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 V D+ +++ + R L+NNAG ++K FV+++ ++ Sbjct: 73 VAGDISKPETADRIVREGIERFGRIDS-----LVNNAGVF--LAKPFVEMTQE-DYDHNL 124 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGW--ALYCAGKAARDMLFQ 182 +N+ +T +V+I++ QP G AL K + + + Sbjct: 125 GVNVAGFFHITQRAAAEMLKQGS--GHIVSITTSLVDQPMVGMPSALASLTKGGLNAVTR 182 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 LA+E VRV +PG + T M + L L G++ + + Sbjct: 183 SLAMEFSRSGVRVNAVSPGVIKTPMHP--------AETHSTLAGLHPVGRMGEIRDVVDA 234 Query: 241 LLSLLEKDEFKSGA--HVD 257 +L LE F +G HVD Sbjct: 235 VL-YLEHAGFITGEILHVD 252 >1H5Q-A nrPDB Length = 265 Score = 124 bits (311), Expect = 5e-29, Method: Composition-based stats. Identities = 46/250 (18%), Positives = 90/250 (36%), Gaps = 26/250 (10%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 ++TG +RG G +A+ + +V+ R+ ++ ++G E G++ Sbjct: 14 NKTIIVTGGNRGIGLAFTRAVAAAGANVAVIY---RSAADAVEVTEKVGKEF-GVKTKAY 69 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ + + + + P LI NAG V K +L+ + + Sbjct: 70 QCDVSNTDIVTKTIQQIDADLGPISG----LIANAGV--SVVKPATELTHE-DFAFVYDV 122 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSL-------CALQPFKGWALYCAGKAARDM 179 N+ + +V K + ++V SS+ +L Y + KAA Sbjct: 123 NVFGVFNTCRAVAKLWLQKQ-QKGSIVVTSSMSSQIINQSSLNGSLTQVFYNSSKAACSN 181 Query: 180 LFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVS 237 L + LA E +RV +PG ++TD +D +R + + Sbjct: 182 LVKGLAAEWASAGIRVNALSPGYVNTDQTA-----HMDKKIRDHQASNIPLNRFAQPEEM 236 Query: 238 AQKLLSLLEK 247 + + LL Sbjct: 237 TGQAILLLSD 246 >3V8B-A nrPDB Length = 283 Score = 124 bits (311), Expect = 5e-29, Method: Composition-based stats. Identities = 58/247 (23%), Positives = 103/247 (41%), Gaps = 21/247 (8%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGA G GR A LA + G + R + ++ E+ +G + + + A Sbjct: 30 VALITGAGSGIGRATALALA---ADGVTVGALGRTRTEVEEVADEIVG--AGGQAIALEA 84 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ E Q+ A+R+L G +++ NAG G + +D + + A+NL Sbjct: 85 DVSDE---LQMRNAVRDLVLKFGH-LDIVVANAGINGVWAP--IDDLKPFEWDETIAVNL 138 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPF--KGWALYCAGKAARDMLFQVLAL 186 + G +V +SS+ + F G Y A KAA+ + Q LAL Sbjct: 139 RGTFLTLHLTVPYLKQRGG--GAIVVVSSINGTRTFTTPGATAYTATKAAQVAIVQQLAL 196 Query: 187 E--EPNVRVLNYAPGPLDTDMQQLAR----ETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 E + ++RV PG ++T++ + E + P Q G+ + A+ Sbjct: 197 ELGKHHIRVNAVCPGAIETNISDNTKLRHEEETAIPVEWPKGQVPITDGQPGRSEDVAEL 256 Query: 241 LLSLLEK 247 + L+ + Sbjct: 257 IRFLVSE 263 >2AG5-A nrPDB Length = 246 Score = 123 bits (309), Expect = 6e-29, Method: Composition-based stats. Identities = 53/251 (21%), Positives = 99/251 (39%), Gaps = 28/251 (11%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G L V +LT A++G G+ A A G+ ++ + N+ L++LE G++ Sbjct: 2 GRLDGKVIILTAAAQGIGQAAALAFAR---EGAKVIATDINESKLQELEKY-----PGIQ 53 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 + D+ + + Q + L +L N AG V G V + + Sbjct: 54 TRVL--DVTKKKQIDQFANEVERLD--------VLFNVAGF---VHHGTVLDCEEKDWDF 100 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLC-ALQPFKGWALYCAGKAARDMLF 181 LN+ SM + + L ++N+SS+ +++ +Y KAA L Sbjct: 101 SMNLNVRSMYLMIKAFLPKMLAQKS--GNIINMSSVASSVKGVVNRCVYSTTKAAVIGLT 158 Query: 182 QVLALE--EPNVRVLNYAPGPLDTD-MQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + +A + + +R PG +DT +Q+ + + R + + G+ + A Sbjct: 159 KSVAADFIQQGIRCNCVCPGTVDTPSLQERIQARGNPEEARNDFLKRQKTGRFATAEEIA 218 Query: 239 QKLLSLLEKDE 249 L L DE Sbjct: 219 -MLCVYLASDE 228 >5ILO-A nrPDB Length = 271 Score = 123 bits (309), Expect = 8e-29, Method: Composition-based stats. Identities = 53/253 (20%), Positives = 97/253 (38%), Gaps = 26/253 (10%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 ++TG + G G ++ L L + + + + + L + L A V+ + Sbjct: 15 GKNAVVTGGAGGIGLQVSKQL--LAAGAAKVAIIDL-QDNLEEFVK-LRAAHPTQSVMII 70 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ + G++ + + +++N AG D V + Sbjct: 71 KMDVANKKGVEATYEEIAKTFG----NIDIVVNVAGIFND-----------KDVQRTLLV 115 Query: 127 NLTSMLCLTSSVLKAF-PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA 185 NL ++ T S L D+ G VVN+SS+ L P +Y A KA + LA Sbjct: 116 NLGGIINSTLSALPYMGKDNGGKGGIVVNMSSVVGLDPMFIIPVYGATKAGIINFTRCLA 175 Query: 186 LEEP----NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 E+ ++ + PG TDM E + P+ + + ++ + Sbjct: 176 NEKYYQRSGIKFVTVCPGATMTDMFTNFTEKIIFPETSDETYRILDRLNKQSAADVSRCI 235 Query: 242 LSLLEKDEFKSGA 254 L++LEKD K+GA Sbjct: 236 LNVLEKD--KNGA 246 >4EGF-A nrPDB Length = 266 Score = 123 bits (308), Expect = 1e-28, Method: Composition-based stats. Identities = 64/245 (26%), Positives = 95/245 (38%), Gaps = 17/245 (6%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TGA++G G A + + + G+ LVLS R+ L LG E+ G V Sbjct: 18 LDGKRALITGATKGIG---ADIARAFAAAGARLVLSGRDVSELDAARRALG-EQFGTDVH 73 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 V DL A R GL +L+NNAG V +D + Sbjct: 74 TVAIDLAEPDA--PAELARRAAEAFGGLD--VLVNNAGISHPQP---VVDTDPQLFDATI 126 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 A+NL + L S+V KA + G ++ ++S AL P YC KA M +VL Sbjct: 127 AVNLRAPALLASAVGKAMVAA-GEGGAIITVASAAALAPLPDHYAYCTSKAGLVMATKVL 185 Query: 185 ALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLL 242 A E +R + P + T+M Q D + G+ + ++ Sbjct: 186 ARELGPHGIRANSVCPTVVLTEMGQRV---WGDEAKSAPMIARIPLGRFAVPHEVSDAVV 242 Query: 243 SLLEK 247 L Sbjct: 243 WLASD 247 >5PGZ-A nrPDB Length = 276 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 50/204 (24%), Positives = 84/204 (41%), Gaps = 18/204 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L ++TGAS+G GR +A L+ + G+ +VL+AR++E L+++ + E Sbjct: 16 LQGKKVIVTGASKGIGREMAYHLSKM---GAHVVLTARSEEGLQKVVSRC-LELGAASAH 71 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + + +Q + +L GL L+L + F D D V Sbjct: 72 YIAGTMEDMTFAEQFIVKAGKL--MGGLDMLILNH---ITQTSLSLFHD--DIHSVRRVM 124 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N S + ++++ L S N ++ ISSL A Y A K A D F + Sbjct: 125 EVNFLSYVVMSTAALPMLKQS---NGSIAVISSLAGKMTQPMIAPYSASKFALDGFFSTI 181 Query: 185 ALEEP----NVRVLNYAPGPLDTD 204 E NV + G +DT+ Sbjct: 182 RTELYITKVNVSITLCVLGLIDTE 205 >3A28-C nrPDB Length = 258 Score = 121 bits (304), Expect = 3e-28, Method: Composition-based stats. Identities = 53/248 (21%), Positives = 101/248 (40%), Gaps = 18/248 (7%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 V ++TG ++G GR ++ LA+ +V L + ++A ++ E + + V V Sbjct: 3 KVAMVTGGAQGIGRGISEKLAADGFDIAVADLPQQEEQAAETIK---LIEAADQKAVFVG 59 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ +A + E + G +L+NNAG K ++++ + +++N Sbjct: 60 LDVTDKANFDSAIDEAAE--KLGGFD--VLVNNAGIAQ--IKPLLEVT-EEDLKQIYSVN 112 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE 187 + S+ + + F + G+ ++N +S+ A+Q F + Y K A L Q A E Sbjct: 113 VFSVFFGIQAASRKFDEL-GVKGKIINAASIAAIQGFPILSAYSTTKFAVRGLTQAAAQE 171 Query: 188 --EPNVRVLNYAPGPLDTDM---QQLARETSVDPDMRKGLQELKAKGKLVDCKVS--AQK 240 V YAPG + T M + + +E + L V Sbjct: 172 LAPKGHTVNAYAPGIVGTGMWEQIDAELSKINGKPIGENFKEYSSSIALGRPSVPEDVAG 231 Query: 241 LLSLLEKD 248 L+S L + Sbjct: 232 LVSFLASE 239 >3OML-A nrPDB Length = 613 Score = 120 bits (301), Expect = 5e-28, Method: Composition-based stats. Identities = 46/232 (19%), Positives = 83/232 (35%), Gaps = 27/232 (11%) Query: 2 EGGL--GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSA----RNDEALRQLEAELG 55 +G L V ++TGA G GR A L A G+ +V++ + + Q A++ Sbjct: 12 DGKLRYDGRVAVVTGAGAGLGREYALLFA---ERGAKVVVNDLGGTHSGDGASQRAADIV 68 Query: 56 AE---RSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFV 112 + ++G V + A + + A++ R +L+NNAG L D S + Sbjct: 69 VDEIRKAGGEAVADYNSVIDGAKVIET--AIKAFGRVD-----ILVNNAGILRDRS---L 118 Query: 113 DLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCA 172 + N ++L T + ++ SS + G Y A Sbjct: 119 VKTSEQDWNLVNDVHLKGSFKCTQAAFPYMKKQNY--GRIIMTSSNSGIYGNFGQVNYTA 176 Query: 173 GKAARDMLFQVLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGL 222 K L +A+E NV P + M + + +++ L Sbjct: 177 AKMGLIGLANTVAIEGARNNVLCNVIVPTA-ASRMTEGILPDILFNELKPKL 227 >2FWM-X nrPDB Length = 250 Score = 120 bits (301), Expect = 6e-28, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 83/254 (32%), Gaps = 39/254 (15%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 +TGA +G G A + G+ + + E+ Sbjct: 5 FSGKNVWVTGAGKGIGYATALAF---VEAGAKVTGFDQ----------AFTQEQYPFATE 51 Query: 65 RVPADLGAEAG----LQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + D+ A Q+LL L L+N AG L G D Sbjct: 52 VM--DVADAAQVAQVCQRLLAETERLDA--------LVNAAGILR---MGATDQLSKEDW 98 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +A+N+ L + F G +V ++S A P G + Y A KAA L Sbjct: 99 QQTFAVNVGGAFNLFQQTMNQFRRQRG--GAIVTVASDAAHTPRIGMSAYGASKAALKSL 156 Query: 181 FQVLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMR-----KGLQELKAKGKLVD 233 + LE VR +PG DTDMQ+ + + R + + GK+ Sbjct: 157 ALSVGLELAGSGVRCNVVSPGSTDTDMQRTLWVSDDAEEQRIRGFGEQFKLGIPLGKIAR 216 Query: 234 CKVSAQKLLSLLEK 247 + A +L L Sbjct: 217 PQEIANTILFLASD 230 >1O5I-A nrPDB Length = 249 Score = 119 bits (298), Expect = 1e-27, Method: Composition-based stats. Identities = 53/246 (21%), Positives = 97/246 (39%), Gaps = 35/246 (14%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 ME G+ L+ ASRG GR +A +L G+ + + ARN+E L+ RSG Sbjct: 13 MELGIRDKGVLVLAASRGIGRAVADVL---SQEGAEVTICARNEELLK---------RSG 60 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 R V DL L L ++E+ +L+ NAG G + F +L++ Sbjct: 61 HR--YVVCDLRK--DLDLLFEKVKEVD--------ILVLNAG--GPKAGFFDELTNE-DF 105 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +M+ + + L A + +V I+S + P + + + A Sbjct: 106 KEAIDSLFLNMIKIVRNYLPAMKEKGW--GRIVAITSFSVISPIENLYTSNSARMALTGF 163 Query: 181 FQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + L+ E + V APG +T+ + + + +K ++ ++ + A Sbjct: 164 LKTLSFEVAPYGITVNCVAPGWTETERVKEL----LSEEKKKQVESQIPMRRMAKPEEIA 219 Query: 239 QKLLSL 244 + L Sbjct: 220 SVVAFL 225 >3GDF-A nrPDB Length = 267 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 45/257 (17%), Positives = 88/257 (34%), Gaps = 23/257 (8%) Query: 4 GLGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGL 61 L V ++TGAS +G G A A + +V + A + + EL G+ Sbjct: 17 SLKGKVVVVTGASGPKGMGIEAARGCAEM--GAAVAITYASRAQGAEENVKELEKT-YGI 73 Query: 62 RVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVN 121 + + + ++L+ + Q I NAG+ D + N Sbjct: 74 KAKAYKCQVDSYESCEKLVKDVV----ADFGQIDAFIANAGATADSGILDGSV---EAWN 126 Query: 122 NYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPF--KGWALYCAGKAARDM 179 + ++L +V F + ++V +S+ + Y KA Sbjct: 127 HVVQVDLNGTFHCAKAVGHHFKERG--TGSLVITASMSGHIANFPQEQTSYNVAKAGCIH 184 Query: 180 LFQVLALEEPNV-RVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + + LA E + RV + +PG +DT + V + ++ + G+ K Sbjct: 185 MARSLANEWRDFARVNSISPGYIDTGLSD-----FVPKETQQLWHSMIPMGRDGLAKELK 239 Query: 239 QKLLSLLEK-DEFKSGA 254 + + +GA Sbjct: 240 GAYVYFASDASTYTTGA 256 >5EJ2-A nrPDB Length = 308 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 51/271 (18%), Positives = 92/271 (33%), Gaps = 33/271 (12%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSA---------RNDEALRQLE 51 M G + V ++GA+RG GR+ A LA + + + E L + Sbjct: 31 MTGRVAGKVAFISGAARGQGRSHAVRLAQEGADIIAIDICGPIENLAYPHSTPEDLAETA 90 Query: 52 AELGAERSGLRVVRVPADLGAEAGLQQLLGA-LRELPRPKGLQRLLLINNAGSLGDVSKG 110 + + R+V D+ L+ + + + +L R +++ NAG D K Sbjct: 91 DLV--KDLDRRIVTAQVDVRDFEALKSAVDSGVEQLGRLD-----IIVANAGVGTDGRK- 142 Query: 111 FVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALY 170 + + +NLT + + + S G ++V SS+ + + Y Sbjct: 143 -LHKIRDNVWQDMIDINLTGVWHTVKAGVPHVL-SGGRGGSIVLTSSVGGRKAYPNTGHY 200 Query: 171 CAGKAARDMLFQVLALE--EPNVRVLNYAPGPLDTD--MQQLARETSVDPDMRKGLQELK 226 A K L + A+E +RV P + T M G + Sbjct: 201 IAAKHGVIGLMRAFAVELGPHMIRVNAVLPTQVSTTMVMNDQTFRLFRPDLENPGPDDFA 260 Query: 227 AKGKL--------VDCKVSAQKLLSLLEKDE 249 ++ VD + +L L DE Sbjct: 261 PISQMMHTLPVPWVDASDISNAVL-FLASDE 290 >4HBG-A nrPDB Length = 286 Score = 118 bits (297), Expect = 2e-27, Method: Composition-based stats. Identities = 59/284 (20%), Positives = 103/284 (36%), Gaps = 51/284 (17%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGL---RVVR 65 V ++TGA+RG G+ + L G ++ E++ + + G +SGL R Sbjct: 6 VAIVTGATRGIGKAICQKLFQ---KGLSCIILGSTKESIERTAIDRGQLQSGLSYQRQCA 62 Query: 66 VPADLGAE---------------AGLQQLLGALRELPRP--------KGLQRLLLINNAG 102 + D L L P + LLIN AG Sbjct: 63 IAIDFKKWPHWLDYESYDGIEYFKDRPPLKQKYSTLFDPCNKWSNNERRYYVNLLINCAG 122 Query: 103 SLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDS---------PGLNRTVV 153 + + ++Q+ + +N S + +T+ +K S T+V Sbjct: 123 LTQ---ESLSVRTTASQIQDIMNVNFMSPVTMTNICIKYMMKSQRRWPELSGQSARPTIV 179 Query: 154 NISSL--CALQPFKGWALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGPLD-TDMQQL 208 NISS+ G ++Y A KAA +VLA +E N+R +PG + TDM Q Sbjct: 180 NISSILHSGKMKVPGTSVYSASKAALSRFTEVLAAEMEPRNIRCFTISPGLVKGTDMIQN 239 Query: 209 ARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFKS 252 + ++ L+ A+++ SL + ++ Sbjct: 240 LP-----VEAKEMLERTIGASGTSAPAEIAEEVWSLYSRTALET 278 >2NWQ-A nrPDB Length = 272 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 54/198 (27%), Positives = 82/198 (41%), Gaps = 17/198 (8%) Query: 12 LTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLG 71 +TGA+ GFG A A G LVL+ R +E L+ L EL A+ RV+ + D+ Sbjct: 26 ITGATSGFGEACARRFA---EAGWSLVLTGRREERLQALAGELSAK---TRVLPLTLDVR 79 Query: 72 AEAGLQQLLGAL-RELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 A + + L E +G LINNAG D + N+ Sbjct: 80 DRAAMSAAVDNLPEEFATLRG-----LINNAGLALGTDP--AQSCDLDDWDTMVDTNIKG 132 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLA--LEE 188 +L T +L + G ++VN+ S+ P+ G +Y KA + L L+ Sbjct: 133 LLYSTRLLLPRLI-AHGAGASIVNLGSVAGKWPYPGSHVYGGTKAFVEQFSLNLRCDLQG 191 Query: 189 PNVRVLNYAPGPLDTDMQ 206 VRV N PG +++ Sbjct: 192 TGVRVTNLEPGLCESEFS 209 >2O23-A nrPDB Length = 265 Score = 118 bits (295), Expect = 3e-27, Method: Composition-based stats. Identities = 51/249 (20%), Positives = 86/249 (34%), Gaps = 27/249 (10%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG + G G A L + G+ VL + +LG V PA Sbjct: 14 VAVITGGASGLGLATAERL---VGQGASAVLLDLPNSGGEAQAKKLGNN-----CVFAPA 65 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDS---TQVNNYWA 125 D+ +E +Q L L + K + + +N AG + + Sbjct: 66 DVTSEKDVQTALA----LAKGKFGRVDVAVNCAGIAVASKTYNLKKGQTHTLEDFQRVLD 121 Query: 126 LNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLF 181 +NL + V PD G ++N +S+ A + G A Y A K + Sbjct: 122 VNLMGTFNVIRLVAGEMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 181 Query: 182 QVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAK-GKLVDCKVSA 238 +A + +RV+ APG T + E + L +L D A Sbjct: 182 LPIARDLAPIGIRVMTIAPGLFGTPLLTSLPEK-----VCNFLASQVPFPSRLGDPAEYA 236 Query: 239 QKLLSLLEK 247 + +++E Sbjct: 237 HLVQAIIEN 245 >2HRB-A nrPDB Length = 274 Score = 117 bits (294), Expect = 4e-27, Method: Composition-based stats. Identities = 62/288 (21%), Positives = 98/288 (34%), Gaps = 69/288 (23%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 G V L+TGA+RG G +A L S +VL+AR+ + +L AE GL Sbjct: 1 GSRVALVTGANRGIGLAIARELCRQFSGD--VVLTARDVARGQAAVQQLQAE--GLSPRF 56 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 D+ ++ ALR+ R + +L+NNA + + Sbjct: 57 HQLDIDDLQSIR----ALRDFLRKEYGGLNVLVNNAAVAFKSDDP---MPFDIKAEMTLK 109 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKG------------------- 166 N + + + +L + VVNISSL L+ F+ Sbjct: 110 TNFFATRNMCNELLPIMK----PHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDL 165 Query: 167 ----------------------WALYCAGKAARDMLFQVLAL---EEPN---VRVLNYAP 198 + Y K +L ++LA E+ + V P Sbjct: 166 VDLMKKFVEDTKNEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCP 225 Query: 199 GPLDTDMQ-----QLARETSVDPDMRKGL--QELKAKGKLVDCKVSAQ 239 GP+ TDM + E + P L + +G+LV KV Sbjct: 226 GPVKTDMDGKDSIRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQN 273 >5O3Z-A nrPDB Length = 263 Score = 117 bits (292), Expect = 7e-27, Method: Composition-based stats. Identities = 46/250 (18%), Positives = 80/250 (32%), Gaps = 20/250 (8%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 V ++ G + G L LA G + ++ N+ +L + + R Sbjct: 6 EQVAVVIGGGQTLGAFLCEGLAQ---AGYHVAVADLNESNANRLADTINSRYGAGRAYGF 62 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D EA ++ L A+ E L L+ +AG L+D + + Sbjct: 63 KVDATDEASVEALARAVDETFGRADL----LVYSAGVAKAAPITQFRLTD---FDLSLQV 115 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 NL + K G+ ++ I+S K + Y A K L Q LAL Sbjct: 116 NLVGYFLCSREFSKLMI-RDGIKGRIIQINSKSGKVGSKHNSGYSAAKFGGVGLTQSLAL 174 Query: 187 E--EPNVRVLNYAPG-PLDTDMQQLARETSVDP------DMRKGLQELKAKGKLVDCKVS 237 + E + V + G L + M Q + ++ + + D + Sbjct: 175 DLAEYGITVHSLMLGNLLKSPMFQSLLPQYAEKLGITPEEVEPYYVDKVPLKRGCDYQDV 234 Query: 238 AQKLLSLLEK 247 LL Sbjct: 235 LNVLLFYASD 244 >1E3W-A nrPDB Length = 261 Score = 116 bits (291), Expect = 8e-27, Method: Composition-based stats. Identities = 52/255 (20%), Positives = 97/255 (38%), Gaps = 28/255 (10%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V ++TG + G G + A L + + ++L N E E A++ G + PA Sbjct: 12 VAVITGGASGLGLSTAKRL--VGQGATAVLLDVPNSEG------ETEAKKLGGNCIFAPA 63 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGS---LGDVSKGFVDLSDSTQVNNYWA 125 ++ +E +Q L +E + + +N AG + + + Sbjct: 64 NVTSEKEVQAALTLAKEKFG----RIDVAVNCAGIAVAIKTYHEKKNQVHTLEDFQRVIN 119 Query: 126 LNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLF 181 +NL + V PD G ++N +S+ A + G A Y A K + Sbjct: 120 VNLIGTFNVIRLVAGVMGQNEPDQGGQRGVIINTASVAAFEGQVGQAAYSASKGGIVGMT 179 Query: 182 QVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAK-GKLVDCKVSA 238 +A + +RV+ APG T + T++ +R L +L D A Sbjct: 180 LPIARDLAPIGIRVVTIAPGLFATPLL-----TTLPDTVRNFLASQVPFPSRLGDPAEYA 234 Query: 239 QKLLSLLEKDEFKSG 253 L+ ++ ++ F +G Sbjct: 235 H-LVQMVIENPFLNG 248 >4DRY-A nrPDB Length = 281 Score = 114 bits (285), Expect = 4e-26, Method: Composition-based stats. Identities = 46/209 (22%), Positives = 76/209 (36%), Gaps = 9/209 (4%) Query: 28 ASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELP 87 +L + G +V++ R + L E+G R+G V V D+G + L A+ Sbjct: 51 QALSAEGYSVVITGRRPDVLDAAAGEIGG-RTGNIVRAVVCDVGDPDQVAALFAAV---- 105 Query: 88 RPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPG 147 R + + LL+NNAG +V ++ Q N A NLT T + Sbjct: 106 RAEFARLDLLVNNAG--SNVPPVPLEEVTFEQWNGIVAANLTGAFLCTQHAFRMMKAQTP 163 Query: 148 LNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALEEP--NVRVLNYAPGPLDTDM 205 ++N S+ A P A Y A K A L + AL+ ++ G TDM Sbjct: 164 RGGRIINNGSISAQTPRPNSAPYTATKHAITGLTKSTALDGRMHDIACGQIDIGNAATDM 223 Query: 206 QQLARETSVDPDMRKGLQELKAKGKLVDC 234 + + + + + Sbjct: 224 TARMSTGVLQANGEVAAEPTIPIEHIAEA 252 >2QHX-A nrPDB Length = 328 Score = 111 bits (277), Expect = 3e-25, Method: Composition-based stats. Identities = 52/274 (18%), Positives = 88/274 (32%), Gaps = 42/274 (15%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGA++ GR++A L + +V + R+ L A L A R + V A Sbjct: 48 VALVTGAAKRLGRSIAEGLHA--EGYAVCLHYHRSAAEANALSATLNARRPN-SAITVQA 104 Query: 69 DLGAEAGL--------------QQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDL 114 DL A + + G +L+NNA S D Sbjct: 105 DLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGR-CDVLVNNASSFYPTPLLRNDE 163 Query: 115 -----------SDSTQVNNYWALNLTSMLCLTSSVLKAFP----DSPGLNRTVVNISSLC 159 + T + + N + L + G N +++N+ Sbjct: 164 DGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAM 223 Query: 160 ALQPFKGWALYCAGKAARDMLFQVLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPD 217 QP G+ +Y K A + L + ALE +RV PG + P Sbjct: 224 TNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL-------SVLVDDMPPA 276 Query: 218 MRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFK 251 + +G + + ++ L + K Sbjct: 277 VWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAK 310 >6CGE-A nrPDB Length = 328 Score = 110 bits (276), Expect = 5e-25, Method: Composition-based stats. Identities = 47/231 (20%), Positives = 83/231 (35%), Gaps = 14/231 (6%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQL-EAELGAERSGLRV 63 + R V L+TG S G G LA LAS S + + R+ + +L EA + Sbjct: 1 MARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSL 60 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + D+ + A RE + +L+ NAG G ++ V + Sbjct: 61 ETLQLDVRDSKS----VAAARERVTEGRVD--VLVCNAGL---GLLGPLEALGEDAVASV 111 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 +N+ + + + L + V+ S+ L +YCA K A + L + Sbjct: 112 LDVNVVGTVRMLQAFLPDM--KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCES 169 Query: 184 LA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLV 232 LA L V + GP+ T + + + R + + + Sbjct: 170 LAVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYL 220 >1A27-A nrPDB Length = 289 Score = 110 bits (276), Expect = 5e-25, Method: Composition-based stats. Identities = 47/230 (20%), Positives = 82/230 (35%), Gaps = 14/230 (6%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQL-EAELGAERSGLRVV 64 R V L+TG S G G LA LAS S + + R+ + +L EA + Sbjct: 1 ARTVVLITGCSSGIGLHLAVRLASDPSQSFKVYATLRDLKTQGRLWEAARALACPPGSLE 60 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + D+ + A RE + +L+ NAG G ++ V + Sbjct: 61 TLQLDVRDSKS----VAAARERVTEGRVD--VLVCNAGL---GLLGPLEALGEDAVASVL 111 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVL 184 +N+ + + + L + V+ S+ L +YCA K A + L + L Sbjct: 112 DVNVVGTVRMLQAFLPDM--KRRGSGRVLVTGSVGGLMGLPFNDVYCASKFALEGLCESL 169 Query: 185 A--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLV 232 A L V + GP+ T + + + R + + + Sbjct: 170 AVLLLPFGVHLSLIECGPVHTAFMEKVLGSPEEVLDRTDIHTFHRFYQYL 219 >2BFA-A nrPDB Length = 288 Score = 110 bits (275), Expect = 6e-25, Method: Composition-based stats. Identities = 52/274 (18%), Positives = 88/274 (32%), Gaps = 42/274 (15%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TGA++ GR++A L + +V + R+ L A L A R + V A Sbjct: 8 VALVTGAAKRLGRSIAEGLHA--EGYAVCLHYHRSAAEANALSATLNARRPN-SAITVQA 64 Query: 69 DLGAEAGL--------------QQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDL 114 DL A + + G +L+NNA S D Sbjct: 65 DLSNVATAPVSGADGSAPVTLFTRCAELVAACYTHWGR-CDVLVNNASSFYPTPLLRNDE 123 Query: 115 -----------SDSTQVNNYWALNLTSMLCLTSSVLKAFP----DSPGLNRTVVNISSLC 159 + T + + N + L + G N +++N+ Sbjct: 124 DGHEPCVGDREAMETATADLFGSNAIAPYFLIKAFAHRVAGTPAKHRGTNYSIINMVDAM 183 Query: 160 ALQPFKGWALYCAGKAARDMLFQVLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPD 217 QP G+ +Y K A + L + ALE +RV PG + P Sbjct: 184 TNQPLLGYTIYTMAKGALEGLTRSAALELAPLQIRVNGVGPGL-------SVLVDDMPPA 236 Query: 218 MRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFK 251 + +G + + ++ L + K Sbjct: 237 VWEGHRSKVPLYQRDSSAAEVSDVVIFLCSSKAK 270 >4CR6-A nrPDB Length = 271 Score = 110 bits (274), Expect = 9e-25, Method: Composition-based stats. Identities = 53/251 (21%), Positives = 87/251 (34%), Gaps = 25/251 (9%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G L ++TGA+ G GR G+ +V L L A R Sbjct: 11 GRLAGKAAIVTGAAGGIGRATVEAYLR---EGASVV--------AMDLAPRLAATRY-EE 58 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 +P + R GL +L+ G+L + F+DLSD + Sbjct: 59 PGAIPIACDLADRAAIDAAMADAVARLGGLD--ILVA-GGALKGGTGNFLDLSD-ADWDR 114 Query: 123 YWALNLTSMLCLTSSVLKAFPD----SPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 Y +N+T + +A G + ++ I S+ + A Y A K Sbjct: 115 YVDVNMTGTFLTCRAGARAMVAAGAGKDGRSARIITIGSVNSFMAEPEAAAYVAAKGGVA 174 Query: 179 MLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKV 236 ML + +A L + V APGP+D +P + + + + A G+ + Sbjct: 175 MLTRAMAVDLARHGILVNMIAPGPVDVTGNNTG---YSEPRLAEQVLDEVALGRPGLPEE 231 Query: 237 SAQKLLSLLEK 247 A + L E Sbjct: 232 VATAAVFLAED 242 >5JY1-A nrPDB Length = 274 Score = 107 bits (268), Expect = 4e-24, Method: Composition-based stats. Identities = 49/262 (18%), Positives = 91/262 (34%), Gaps = 24/262 (9%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G L + V L+TGA + S + G+ ++++ N+ RQ+E E+ G R Sbjct: 10 GLLEQRVALVTGAGG---GIGRGVARSFGNEGAAVIIAEINESTGRQVEQEI--REMGGR 64 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 + V D+ ++A ++ + + E +L+NNA ++ + Sbjct: 65 SLFVKTDVTSKASIEAAVRSAVEQFGS----LDILVNNA--FVPTPNVLLEEKTDEMLEQ 118 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 +L + + + +VN S+ Y KA L + Sbjct: 119 TLTTSLWATWWAMRAAFVPMRERRW--GRIVNFYSIDTETGAWLHGDYNTAKAGIVGLTR 176 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARE-TSVDPDMRKGLQELKAKGKLVDCKVSAQ 239 A E N+ V AP T M E + +P+ + + G+ D + Sbjct: 177 SAASEWGRFNITVNAIAP----TAMGATFFELAAKNPEFAERSAAARPLGRSGDPEQDIG 232 Query: 240 KLLSLLEKD--EFKSGA--HVD 257 + F +G HVD Sbjct: 233 PAAVFFASEMSRFVTGETLHVD 254 >4FC7-A nrPDB Length = 277 Score = 107 bits (266), Expect = 7e-24, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 88/243 (36%), Gaps = 19/243 (7%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L V +TG G G +A + + G V+++R+ + +L +G R + Sbjct: 25 LRDKVAFITGGGSGIGFRIAEIF---MRHGCHTVIASRSLPRVLTAARKLAG-ATGRRCL 80 Query: 65 RVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + D+ A + + AL+E R +LIN A G + Sbjct: 81 PLSMDVRAPPAVMAAVDQALKEFGRID-----ILINCAAGNFLCPAGALS---FNAFKTV 132 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 ++ + ++ + + F +VNI++ + + KAA D + + Sbjct: 133 MDIDTSGTFNVSRVLYEKFF--RDHGGVIVNITATLGNRGQALQVHAGSAKAAVDAMTRH 190 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 LA+E N+RV + APGP+ + R +L + A + Sbjct: 191 LAVEWGPQNIRVNSLAPGPI--SGTEGLRRLGGPQASLSTKVTASPLQRLGNKTEIAHSV 248 Query: 242 LSL 244 L L Sbjct: 249 LYL 251 >3E9N-A nrPDB Length = 245 Score = 106 bits (264), Expect = 1e-23, Method: Composition-based stats. Identities = 53/256 (20%), Positives = 96/256 (37%), Gaps = 33/256 (12%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L + + ++TGA+ G G + L+ ++ RN E L L G E Sbjct: 2 SLKKKIAVVTGATGGMGIEIVKDLSRDH----IVYALGRNPEHLAALAEIEGVEP----- 52 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + +D+ E + + L+ L L++ A D + + + + + Sbjct: 53 --IESDIVKEVLEEGGVDKLKNLDHVD-----TLVHAAAVARDTTIEAGSV---AEWHAH 102 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 LN+ L+ +L A + V+ I+S P G +Y A K A L Sbjct: 103 LDLNVIVPAELSRQLLPAL---RAASGCVIYINSGAGNGPHPGNTIYAASKHALRGLADA 159 Query: 184 LALEEPN--VRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 EE N +RV +PGP +T M Q ++ + R + ++ K A + Sbjct: 160 FRKEEANNGIRVSTVSPGPTNTPMLQGLMDSQ-GTNFRPEI--------YIEPKEIANAI 210 Query: 242 LSLLEKDEFKSGAHVD 257 +++ E +VD Sbjct: 211 RFVIDAGETTQITNVD 226 >1P33-A nrPDB Length = 289 Score = 105 bits (261), Expect = 3e-23, Method: Composition-based stats. Identities = 49/271 (18%), Positives = 89/271 (32%), Gaps = 44/271 (16%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSA-RNDEALRQLEAELGAERSGLRVVRVP 67 V L+TGA++ G ++A L + G + L R+ L A L A R + V Sbjct: 9 VALVTGAAKRLGSSIAEALH---AEGYTVCLHYHRSAADASTLAATLNARRPN-SAITVQ 64 Query: 68 ADLGAEAGLQ--------------QLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVD 113 ADL A + + G +L+NNA S D Sbjct: 65 ADLSNVATASFSETDGSVPVTLFSRCSALVDACYMHWGR-CDVLVNNASSFYPTPLLRKD 123 Query: 114 -------LSDSTQVN----NYWALNLTSMLCLTSSVLKAFP----DSPGLNRTVVNISSL 158 + D + + + N + L + + + G + ++VN+ Sbjct: 124 AGEGGSSVGDKESLEVAAADLFGSNAIAPYFLIKAFAQRVADTRAEQRGTSYSIVNMVDA 183 Query: 159 CALQPFKGWALYCAGKAARDMLFQVLALEEPN--VRVLNYAPGPLDTDMQQLARETSVDP 216 QP G+ +Y K A + L + ALE + +RV +PG + Sbjct: 184 MTSQPLLGYTMYTMAKEALEGLTRSAALELASLQIRVNGVSPGL-------SVLPDDMPF 236 Query: 217 DMRKGLQELKAKGKLVDCKVSAQKLLSLLEK 247 +++ + + ++ L Sbjct: 237 SVQEDYRRKVPLYQRNSSAEEVSDVVIFLCS 267 >4GKB-A nrPDB Length = 258 Score = 104 bits (259), Expect = 4e-23, Method: Composition-based stats. Identities = 54/251 (21%), Positives = 88/251 (35%), Gaps = 23/251 (9%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 M+ L V ++TG + G G ++ LA + V A + L L + Sbjct: 1 MDLNLQDKVVIVTGGASGIGGAISMRLAEERAIPVVFARHAPDGAFLDALA------QRQ 54 Query: 61 LRVVRVPADLGAEAGLQQLLG-ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119 R +P +L +A + + + R G L+NNAG + Sbjct: 55 PRATYLPVELQDDAQCRDAVAQTIATFGRLDG-----LVNNAGVNDGIGLDAGR----DA 105 Query: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 NL + + + G +VNISS A+ + YCA K A+ Sbjct: 106 FVASLERNLIHYYAMAHYCVPHLKATRGA---IVNISSKTAVTGQGNTSGYCASKGAQLA 162 Query: 180 LFQ--VLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMR-KGLQELKAKG-KLVDCK 235 L + +AL E VRV P + T + + T DP+ + + G + Sbjct: 163 LTREWAVALREHGVRVNAVIPAEVMTPLYRNWIATFEDPEAKLAEIAAKVPLGRRFTTPD 222 Query: 236 VSAQKLLSLLE 246 A + LL Sbjct: 223 EIADTAVFLLS 233 >3BHI-A nrPDB Length = 276 Score = 101 bits (251), Expect = 4e-22, Method: Composition-based stats. Identities = 55/286 (19%), Positives = 93/286 (32%), Gaps = 71/286 (24%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V L+TG ++G G + L L S +VL+AR+ + +L AE GL Sbjct: 6 VALVTGGNKGIGLAIVRDLCRLFSGD--VVLTARDVTRGQAAVQQLQAE--GLSPRFHQL 61 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 D+ ++ L LR+ GL +L+NNAG ++D T + + + Sbjct: 62 DIDDLQSIRALRDFLRK--EYGGLD--VLVNNAGIA-------FKVADPTPFHIQAEVTM 110 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQ-------------------------- 162 + T V VVN+SS+ +++ Sbjct: 111 KTNFFGTRDVCTELLPLIKPQGRVVNVSSIMSVRALKSCSPELQQKFRSETITEEELVGL 170 Query: 163 ----------------PFKGWALYCAGKAARDMLFQVLAL---EEPN---VRVLNYAPGP 200 + + Y K +L ++ A E+ + + PG Sbjct: 171 MNKFVEDTKKGVHQKEGWPS-SAYGVTKIGVTVLSRIHARKLSEQRKGDKILLNACCPGW 229 Query: 201 LDTDM-----QQLARETSVDPDMRKGL--QELKAKGKLVDCKVSAQ 239 + TDM + E + P L G+ V K Q Sbjct: 230 VRTDMAGPKATKSPEEGAETPVYLALLPPDAEGPHGQFVSEKRVEQ 275 >2BGM-A nrPDB Length = 278 Score = 100 bits (249), Expect = 7e-22, Method: Composition-based stats. Identities = 38/231 (16%), Positives = 81/231 (35%), Gaps = 17/231 (7%) Query: 24 APLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGAL 83 A L G+ +V++ D+ +++ +G+ + V D+ + ++ L+ Sbjct: 33 AKLFVRY---GAKVVIADIADDHGQKVCNNIGSPDV---ISFVHCDVTKDEDVRNLVDT- 85 Query: 84 RELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFP 143 + + L ++ N G L ++ + +N+ + + Sbjct: 86 -TIAKHGKLD--IMFGNVGVLSTTPYSILEAGNE-DFKRVMDINVYGAFLVAKHAARVMI 141 Query: 144 DSPGLNRTVVNISSLCALQPFKGWAL-YCAGKAARDMLFQVLALE--EPNVRVLNYAPGP 200 P ++V +S+ + +G + Y A K A L L E E +RV +P Sbjct: 142 --PAKKGSIVFTASISSFTAGEGVSHVYTATKHAVLGLTTSLCTELGEYGIRVNCVSPYI 199 Query: 201 LDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLEKDEFK 251 + + + Q KG L+ + A ++ L DE K Sbjct: 200 VASPLLTDVFGVDSSRVEELAHQAANLKGTLLRAEDVADA-VAYLAGDESK 249 >5L51-A nrPDB Length = 324 Score = 98.6 bits (244), Expect = 2e-21, Method: Composition-based stats. Identities = 52/284 (18%), Positives = 94/284 (33%), Gaps = 88/284 (30%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND----EALRQLEAELGA 56 ++ + ++TGA++G G + LAS G ++L++R++ EA +L ELG+ Sbjct: 9 VDHAATKRYAVVTGANKGIGFEICKQLAS---KGITVILASRDEKRGIEARERLIKELGS 65 Query: 57 ERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSD 116 E G VV D+ A + AL + + K +L+NNAG G +G + + Sbjct: 66 EF-GDYVVSQQLDVADPAS----VAALVDFIKTKFGSLDILVNNAGLNGTYMEGDASVLN 120 Query: 117 S-------------------------------TQVNNYWALNLTSMLCLTSSVLKAFPDS 145 N +T +++ S Sbjct: 121 DYVEAEFKTFQSGAAKTEPYHPKATGRLVETVEHAKECIETNYYGSKRVTEALIPLLQQS 180 Query: 146 PGLNRTVVNISSLCALQPF----------------------------------------- 164 +VN+SS + F Sbjct: 181 DSP--RIVNVSSTLSSLVFQTNEWAKGVFSSEEGLTEEKLEEVLAEFLKDFIDGKQQEKQ 238 Query: 165 --KGWALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQ 206 ++ Y KAA + +++A + P+ R+ PG TD+ Sbjct: 239 WPPHFSAYKVSKAALNAYTRIIAKKYPSFRINAVCPGYTKTDLS 282 >3U4C-A nrPDB Length = 281 Score = 96.7 bits (239), Expect = 9e-21, Method: Composition-based stats. Identities = 38/256 (14%), Positives = 88/256 (34%), Gaps = 27/256 (10%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 + + + GAS+G G+ +A LA LV+++RN + + ++ ++ A+ V+ Sbjct: 21 MSKRTAFVMGASQGIGKAIALKLADQHFS---LVINSRNLDNIESVKEDILAKHPEASVI 77 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 + D+ + + + + L +LINN + + D + + + Sbjct: 78 VLAGDMSDQHTRAGIFQKIE--SQCGRLD--VLINN---IPGGAPDTFDNCNIEDMTATF 130 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ-- 182 + + + ++NI +P AA + Sbjct: 131 TQKTVAYIDAIKRASSLMKQNEF--GRIINIVGNLWKEPGANMFTNSMMNAALINASKNI 188 Query: 183 VLALEEPNVRVLNYAPGPLDTD---------MQQLARETSVDPDMRKGLQELKAKGKLVD 233 + L N+ V PG + TD M++ + + + ++ Sbjct: 189 SIQLAPHNITVNCLNPGFIATDRYHQFVENVMKKNSISKQKAEEQ---IASGIPMKRVGS 245 Query: 234 CKVSAQKLLSLLEKDE 249 + +A L + L +E Sbjct: 246 AEETA-ALAAFLASEE 260 >4RGB-A nrPDB Length = 294 Score = 95.9 bits (237), Expect = 1e-20, Method: Composition-based stats. Identities = 54/267 (20%), Positives = 94/267 (35%), Gaps = 35/267 (13%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND------------EALRQL 50 G L V +TGA+RG GR+ A + A G+ +V + E L + Sbjct: 21 GSLDGRVVFITGAARGQGRSHAVMCA---EQGANIVGVDICEDIDIVPYKLGTYEELEET 77 Query: 51 EAELGAERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKG 110 + E++G ++ AD+ +A LQ++ A E +I NAG V Sbjct: 78 ARLV--EKTGQEMLFRKADVRDKAVLQEVFDAGVEQFGH----IDTVIANAGV---VLTN 128 Query: 111 FVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQ----PFKG 166 + S + + L + + + G ++ SS+ AL G Sbjct: 129 PDERDASEALRLGLDIMLIGVWNTFQVAIPHMKE-RGQGGNLIATSSMIALLDLTDGRGG 187 Query: 167 WALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGPLDTDMQ----QLARETSVDPDMRK 220 Y K A L + A L +RV AP T M L + +P + Sbjct: 188 TDAYLTSKLAITGLVRSYALMLAADRIRVNGVAPTNCSTPMITENPALFKVIEENPHLVN 247 Query: 221 GLQELKAKGKLVDCKVSAQKLLSLLEK 247 + +++ + + +L L+ Sbjct: 248 AMSTALPDFPMIEPRDVSNAILFLISD 274 >1N5D-A nrPDB Length = 288 Score = 95.5 bits (236), Expect = 2e-20, Method: Composition-based stats. Identities = 47/255 (18%), Positives = 79/255 (30%), Gaps = 62/255 (24%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 V L+TGA++G G + L + +VL+AR+ + +L AE GL Sbjct: 3 NTRVALVTGANKGIGFAIVRDLCRQFAGD--VVLTARDVARGQAAVKQLQAE--GLSPRF 58 Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 D+ ++ L LR+ GL +L+NNA + Q Sbjct: 59 HQLDIIDLQSIRALCDFLRK--EYGGLD--VLVNNAAIAFQLDNP---TPFHIQAELTMK 111 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPF--------------------- 164 N + + +L VVN+SS ++ Sbjct: 112 TNFMGTRNVCTELLPLIKPQ----GRVVNVSSTEGVRALNECSPELQQKFKSETITEEEL 167 Query: 165 ------------------KGWAL--YCAGKAARDMLFQVLALEEP------NVRVLNYAP 198 +GW+ Y K +L ++ A + + + P Sbjct: 168 VGLMNKFVEDTKNGVHRKEGWSDSTYGVTKIGVSVLSRIYARKLREQRAGDKILLNACCP 227 Query: 199 GPLDTDMQQLARETS 213 G + TDM S Sbjct: 228 GWVRTDMGGPKAPKS 242 >3PPI-A nrPDB Length = 281 Score = 94.0 bits (232), Expect = 6e-20, Method: Composition-based stats. Identities = 46/252 (18%), Positives = 81/252 (32%), Gaps = 26/252 (10%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 A +++G + G G L + G +V++ E + L EL G R Sbjct: 26 KQFEGASAIVSGGAGGLGEATVRRLH---ADGLGVVIADLAAEKGKALADEL-----GNR 77 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAG--SLGDVSKGFVDLSDSTQV 120 V ++ +E + + A +L R R ++ + G + + +D Sbjct: 78 AEFVSTNVTSEDSVLAAIEAANQLGRL----RYAVVAHGGFGVAQRIVQRDGSPADMGGF 133 Query: 121 NNYWALNLTSMLCLTSSVLKAF----PDSPGLNRTVVNISSLCALQPFKGWALYCAGKAA 176 L L + V + P G +V +S+ + G Y A KA Sbjct: 134 TKTIDLYLNGTYNVARLVAASIAAAEPRENGERGALVLTASIAGYEGQIGQTAYAAAKAG 193 Query: 177 RDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAK-GKLVD 233 L A + +RV APG + T + + E ++ +L Sbjct: 194 VIGLTIAAARDLSSAGIRVNTIAPGTMKTPIMESVGEEAL-----AKFAANIPFPKRLGT 248 Query: 234 CKVSAQKLLSLL 245 A LL Sbjct: 249 PDEFADAAAFLL 260 >3O26-A nrPDB Length = 311 Score = 93.2 bits (230), Expect = 1e-19, Method: Composition-based stats. Identities = 50/307 (16%), Positives = 92/307 (29%), Gaps = 84/307 (27%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 R ++TG ++G G + L S G ++VL+ R+ + +L + VV Sbjct: 12 RRCAVVTGGNKGIGFEICKQL---SSNGIMVVLTCRDVTKGHEAVEKL-KNSNHENVVFH 67 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLG---DVSKGFVDLSDSTQV--- 120 D+ + +L + + + +L+NNAG G D + +SD + Sbjct: 68 QLDVTDP---IATMSSLADFIKTHFGKLDILVNNAGVAGFSVDADRFKAMISDIGEDSEE 124 Query: 121 ---------------------NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLC 159 +N + +T ++ S +VN+SS Sbjct: 125 LVKIYEKPEAQELMSETYELAEECLKINYNGVKSVTEVLIPLLQLSDSP--RIVNVSSST 182 Query: 160 ALQ------------------------------------------PFKGW-ALYCAGKAA 176 + + A Y KA Sbjct: 183 GSLKYVSNETALEILGDGDALTEERIDMVVNMLLKDFKENLIETNGWPSFGAAYTTSKAC 242 Query: 177 RDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLA----RETSVDPDMR-KGLQELKAKGKL 231 + +VLA + P +V PG + T+M E + +R + G Sbjct: 243 LNAYTRVLANKIPKFQVNCVCPGLVKTEMNYGIGNYTAEEGAEHVVRIALFPDDGPSGFF 302 Query: 232 VDCKVSA 238 DC + Sbjct: 303 YDCSELS 309 >5WQO-A nrPDB Length = 234 Score = 91.3 bits (225), Expect = 4e-19, Method: Composition-based stats. Identities = 58/212 (27%), Positives = 87/212 (41%), Gaps = 21/212 (9%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+ GASRG G LA L G+ + AR + L+A AER+G R+ V D Sbjct: 9 VLIVGASRGIGLGLADAF---LQRGAQVFAVARRPQGSPGLQAL--AERAGERLQAVTGD 63 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 L +++ L E + + RL++ NAG G + ++ D+ Q + N Sbjct: 64 LNQHDCAERIGEMLGE----RRIDRLIV--NAGIYGPQQQDVAEI-DAEQTAQLFLTNAI 116 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWA---LYCAGKAARDMLFQVL-- 184 + L L +A V +SS A A LY A KAA + L + Sbjct: 117 APLRL----ARALSGRVSRGGVVAFMSSQMASLALGLSATMPLYGASKAALNSLVRSWEG 172 Query: 185 ALEEPNVRVLNYAPGPLDTDMQQLARETSVDP 216 EE +L PG + T+M + SV+ Sbjct: 173 EFEELPFSLLLLHPGWVRTEMGGDSAPLSVEE 204 >3PXX-A nrPDB Length = 287 Score = 90.9 bits (224), Expect = 6e-19, Method: Composition-based stats. Identities = 54/281 (19%), Positives = 94/281 (33%), Gaps = 52/281 (18%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSA------RNDEAL----RQLEA 52 G + V L+TG +RG GR+ A LA G+ ++L N+ L EA Sbjct: 6 GRVQDKVVLVTGGARGQGRSHAVKLA---EEGADIILFDICHDIETNEYPLATSRDLEEA 62 Query: 53 ELGAERSGLRVVRVPADLGAEAGL-QQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGF 111 L E++G + D+ A + ++L A+ E + +++ NAG + Sbjct: 63 GLEVEKTGRKAYTAEVDVRDRAAVSRELANAVAEFGKLD-----VVVANAGICPLGAHL- 116 Query: 112 VDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQ--------- 162 + + ++ ++ + L +++ S+ L Sbjct: 117 ----PVQAFADAFDVDFVGVINTVHAALPYLTS----GASIITTGSVAGLIAAAQPPGAG 168 Query: 163 --PFKGWALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLA------RET 212 G A Y K D LA L ++R P ++TDM A R Sbjct: 169 GPQGPGGAGYSYAKQLVDSYTLQLAAQLAPQSIRANVIHPTNVNTDMLNSAPMYRQFRPD 228 Query: 213 SVDPDMRKGLQELKAKGKL----VDCKVSAQKLLSLLEKDE 249 P L A + V+ + + L DE Sbjct: 229 LEAPSRADALLAFPAMQAMPTPYVEASDISNA-VCFLASDE 268 >1B15-A nrPDB Length = 254 Score = 89.0 bits (219), Expect = 2e-18, Method: Composition-based stats. Identities = 49/219 (22%), Positives = 79/219 (36%), Gaps = 24/219 (10%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L + A G G + L V++ N AL AEL A + + Sbjct: 3 LTNKNVIFVAALGGIGLDTSRELVKRNLKNFVILDRVENPTAL----AELKAINPKVNIT 58 Query: 65 RVPADLGAE-AGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 D+ A ++LL + + K + +LIN AG L D Q+ Sbjct: 59 FHTYDVTVPVAESKKLLKKI--FDQLKTVD--ILINGAGILDDH-----------QIERT 103 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVV-NISSLCALQPFKGWALYCAGKAARDMLFQ 182 A+N T ++ T+++L + G ++ NI S+ +Y A KAA Sbjct: 104 IAINFTGLVNTTTAILDFWDKRKGGPGGIIANICSVTGFNAIHQVPVYSASKAAVVSFTN 163 Query: 183 VLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMR 219 LA P V + PG T + + +D + R Sbjct: 164 SLAKLAPITGVTAYSINPGITRTPLVHTFN-SWLDVEPR 201 >1W73-A nrPDB Length = 302 Score = 88.6 bits (218), Expect = 2e-18, Method: Composition-based stats. Identities = 49/261 (18%), Positives = 101/261 (38%), Gaps = 23/261 (8%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 V +TG G G+ + LL+SL G+ V+++R + L+ ++ + ++G +V Sbjct: 23 SFQGKVAFITGGGTGLGKGMTTLLSSL---GAQCVIASRKMDVLKATAEQISS-QTGNKV 78 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + D+ +Q + L ++ ++INNA + + + + Sbjct: 79 HAIQCDVRDPDMVQNTVSELIKVAGH----PNIVINNAAGNFISPTERLSPNAWKTITDI 134 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 L +T + K + ++I+++ A + KA + + + Sbjct: 135 V---LNGTAFVTLEIGKQLIKAQK-GAAFLSITTIYAETGSGFVVPSASAKAGVEAMSKS 190 Query: 184 LALE--EPNVRVLNYAPGPLDTDMQQLARETSVDP--DMRKGLQELKAKGKLVDCKVSAQ 239 LA E + +R PGP+ T + +DP K + G+L + A Sbjct: 191 LAAEWGKYGMRFNVIQPGPIKT----KGAFSRLDPTGTFEKEMIGRIPCGRLGTVEELAN 246 Query: 240 KLLSLLEKD--EFKSGAHVDF 258 L + L D + +GA + F Sbjct: 247 -LAAFLCSDYASWINGAVIKF 266 >5TQV-A nrPDB Length = 233 Score = 88.2 bits (217), Expect = 3e-18, Method: Composition-based stats. Identities = 46/199 (23%), Positives = 81/199 (40%), Gaps = 20/199 (10%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 L+ GASRG GR G ++ +AR+D +L L A L Sbjct: 10 KTVLIVGASRGLGREFVRQYQR---DGWNVIATARDDASLAALRA--------LGAHAHA 58 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 D+ + AL + L +++ +G G ++G V+ S + N Sbjct: 59 LDITQPEQ----IAALGWKLDGERLDVAVVV--SGVYGPRTEG-VETIASDDFDTVMHTN 111 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVN-ISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 + + L +L D+ G+ V + + S+ GW LY A KAA + + ++ +L Sbjct: 112 VRGPMQLLPILLPLVEDARGVLAVVSSRMGSISEATGTTGW-LYRASKAALNDVLRIASL 170 Query: 187 EEPNVRVLNYAPGPLDTDM 205 + + ++ PG + TDM Sbjct: 171 QTRHAACISLHPGWVRTDM 189 >5LCX-A nrPDB Length = 316 Score = 87.4 bits (215), Expect = 5e-18, Method: Composition-based stats. Identities = 56/318 (17%), Positives = 97/318 (30%), Gaps = 89/318 (27%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER--SGLRVV 64 + L+TGA++G G + LA G +++L++RN++ + +L E S R+V Sbjct: 7 QRYALVTGANKGIGFEICRQLA---EKGIIVILTSRNEKRGLEARQKLLKELNVSENRLV 63 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLG------------------- 105 D+ A + A+ + K + +L+NNAG G Sbjct: 64 FHQLDVTDLAS----VAAVAVFIKSKFGKLDILVNNAGVSGVEMVGDVSVFNEYIEADFK 119 Query: 106 ---------DVSKGFVDLSDSTQVN------NYWALNLTSMLCLTSSVLKAFPDSPGLNR 150 F ++ + + N LT +++ SP Sbjct: 120 ALQALEAGAKEEPPFKPKANGEMIEKFEGAKDCVVTNYYGPKRLTQALIPLLQLSPSP-- 177 Query: 151 TVVNI-------------------------------------------SSLCALQPFKGW 167 +VN+ L Q + Sbjct: 178 RIVNVSSSFGSLLLLWNEWAKGVLGDEDRLTEERVDEVVEVFLKDIKEGKLEESQWPPHF 237 Query: 168 ALYCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETS-VDPDMRKGLQELK 226 A KAA + ++ A + P+ R+ PG TD+ A S + L Sbjct: 238 AAERVSKAALNAYTKIAAKKYPSFRINAICPGYAKTDITFHAGPLSVAEAAQVPVKLALL 297 Query: 227 AKGKLVDCKVSAQKLLSL 244 G C K L+L Sbjct: 298 PDGGPSGCFFPRDKALAL 315 >1MG5-A nrPDB Length = 255 Score = 85.1 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 49/243 (20%), Positives = 79/243 (32%), Gaps = 24/243 (9%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L + G G + L LV+ R + AEL A + V Sbjct: 3 TLTNKNVIFVAGLGGIGLDTSKELLKRDLK--NLVILDRIENPA--AIAELKAINPKVTV 58 Query: 64 VRVPADLGAE-AGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 P D+ A +LL + + +LIN AG L D Q+ Sbjct: 59 TFYPYDVTVPIAETTKLLKTIFAQLKT----VDVLINGAGILDDH-----------QIER 103 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVV-NISSLCALQPFKGWALYCAGKAARDMLF 181 A+N T ++ T+++L + G ++ NI S+ +Y KAA Sbjct: 104 TIAVNYTGLVNTTTAILDFWDKRKGGPGGIICNIGSVTGFNAIYQVPVYSGTKAAVVNFT 163 Query: 182 QVLALEEP--NVRVLNYAPGPLDTDMQQLARE-TSVDPDMRKGLQELKAKGKLVDCKVSA 238 LA P V PG T + V+P + + L + L + Sbjct: 164 SSLAKLAPITGVTAYTVNPGITRTTLVHKFNSWLDVEPQVAEKLLAHPTQPSLACAENFV 223 Query: 239 QKL 241 + + Sbjct: 224 KAI 226 >3OIG-A nrPDB Length = 266 Score = 78.2 bits (191), Expect = 3e-15, Method: Composition-based stats. Identities = 39/262 (14%), Positives = 82/262 (31%), Gaps = 40/262 (15%) Query: 1 MEGGLGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER 58 M L ++ G + R +A SL G+ L+ + E L + EL Sbjct: 1 MNFSLEGRNIVVMGVANKRSIAWGIAR---SLHEAGARLIFTY-AGERLEKSVHELAGTL 56 Query: 59 SGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST 118 + +P D+ +A ++ +++E G + ++ + Sbjct: 57 DRNDSIILPCDVTNDAEIETCFASIKEQV--------------GVIHGIAHCIAFANKEE 102 Query: 119 QVNNYWALNLTSMLC-----------LTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGW 167 V Y N L + + + ++V ++ L + Sbjct: 103 LVGEYLNTNRDGFLLAHNISSYSLTAVVKAARPMMTE----GGSIVTLTYLGGELVMPNY 158 Query: 168 ALYCAGKAARDMLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQEL 225 + KA+ D + LA L + N+RV + + GP+ T + + K ++E Sbjct: 159 NVMGVAKASLDASVKYLAADLGKENIRVNSISAGPIRT-LSAKGISDFNS--ILKDIEER 215 Query: 226 KAKGKLVDCKVSAQKLLSLLEK 247 + + L Sbjct: 216 APLRRTTTPEEVGDTAAFLFSD 237 >5YCX-A nrPDB Length = 266 Score = 76.2 bits (186), Expect = 1e-14, Method: Composition-based stats. Identities = 44/255 (17%), Positives = 90/255 (35%), Gaps = 34/255 (13%) Query: 5 LGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 L ++ G + R +A L + G+ L+ + E L + EL G Sbjct: 6 LQGKTFVVMGVANQRSIAWGIARSLHN---AGAKLIFTY-AGERLERNVRELADTLEGQE 61 Query: 63 VVRVPADLGAEAGLQQLLGAL-RELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVN 121 + +P D+ + L + +E+ G+ + N D KG + D+++ Sbjct: 62 SLVLPCDVTNDEELTACFETIKQEVGTIHGVAHCIAFAN----RDDLKG--EFVDTSRDG 115 Query: 122 NYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLF 181 A N+ S LT +V + ++ ++ L + K + + KA+ + Sbjct: 116 FLLAQNI-SAFSLT-AVAREAKKVMTEGGNILTLTYLGGERVVKNYNVMGVAKASLEASV 173 Query: 182 QVLALE--EPNVRVLNYAPGPLDT-------DMQQLARETSVDPDMRKGLQELKAKGKLV 232 + LA + + +RV + GP+ T D + RE ++E + Sbjct: 174 KYLANDLGQHGIRVNAISAGPIRTLSAKGVGDFNSILRE----------IEERAPLRRTT 223 Query: 233 DCKVSAQKLLSLLEK 247 + + L Sbjct: 224 TQEEVGDTAVFLFSD 238 >4M89-A nrPDB Length = 261 Score = 75.1 bits (183), Expect = 3e-14, Method: Composition-based stats. Identities = 43/252 (17%), Positives = 88/252 (34%), Gaps = 24/252 (9%) Query: 3 GGLGRAVCLLTG--ASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+TG + R +A + + + + +E +R++ AEL +E Sbjct: 2 GFLQGKKILITGMISERSIAYGIAKACREQGAELAFTYVVDKLEERVRKMAAELDSE--- 58 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGD--VSKGFVDLSDST 118 + D+ ++ + Q+ L + GL L+++ G +S F+D Sbjct: 59 ---LVFRCDVASDDEINQVFADLGK--HWDGLDG--LVHSIGFAPKEALSGDFLDSISRE 111 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 N ++ S+ L + G N +V +S L A++ + + KA+ + Sbjct: 112 AFNTAHEISAYSLPALAKAARPMM---RGRNSAIVALSYLGAVRAIPNYNVMGMAKASLE 168 Query: 179 M---LFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235 L + +R + GP+ T A + + + + V + Sbjct: 169 AGIRFT-AACLGKEGIRCNGISAGPIKT---LAASGIADFGKLLGHVAAHNPLRRNVTIE 224 Query: 236 VSAQKLLSLLEK 247 LL Sbjct: 225 EVGNTAAFLLSD 236 >2P91-A nrPDB Length = 285 Score = 75.1 bits (183), Expect = 3e-14, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 81/205 (39%), Gaps = 16/205 (7%) Query: 3 GGLGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+TG + R +A + + + + ++ +R++ G++ Sbjct: 17 GLLEGKRALITGVANERSIAYGIAKSFHREGAQLAFTYATPKLEKRVREIAKGFGSD--- 73 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 + V D+ + ++ L L E G +++ + A + + KG V + Sbjct: 74 ---LVVKCDVSLDEDIKNLKKFLEE---NWGSLDIIVHSIAYAPKEEFKGGVIDTSREGF 127 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 +++ S++ LT +L G N +V +S A + + + KAA + Sbjct: 128 KIAMDISVYSLIALTRELLPLME---GRNGAIVTLSYYGAEKVVPHYNVMGIAKAALEST 184 Query: 181 FQVLALE--EPNVRVLNYAPGPLDT 203 + LA + + R+ + GP+ T Sbjct: 185 VRYLAYDIAKHGHRINAISAGPVKT 209 >2YW9-A nrPDB Length = 261 Score = 74.3 bits (181), Expect = 5e-14, Method: Composition-based stats. Identities = 43/246 (17%), Positives = 84/246 (34%), Gaps = 20/246 (8%) Query: 5 LGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 L L+ G + R G +A L + ++ + R +L LG Sbjct: 6 LSGKKALVMGVTNQRSLGFAIAAKLKEAGAEVALSYQAERLRPEAEKLAEALGG------ 59 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 + AD+ + L L ++E GL L+ +A + D+ + + Sbjct: 60 ALLFRADVTQDEELDALFAGVKEAF--GGLDYLV---HAIAFAPREAMEGRYIDTRRQDW 114 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 AL +++ + +V + +V ++ + + + + KAA + + Sbjct: 115 LLALEVSAYSLV--AVARRAEPLLREGGGIVTLTYYASEKVVPKYNVMAIAKAALEASVR 172 Query: 183 VLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 LA E VRV + GP+ T AR M + + + + + Sbjct: 173 YLAYELGPKGVRVNAISAGPVRT---VAARSIPGFTKMYDRVAQTAPLRRNITQEEVGNL 229 Query: 241 LLSLLE 246 L LL Sbjct: 230 GLFLLS 235 >5I9N-A nrPDB Length = 276 Score = 71.2 bits (173), Expect = 5e-13, Method: Composition-based stats. Identities = 45/251 (17%), Positives = 89/251 (35%), Gaps = 23/251 (9%) Query: 3 GGLGRAVCLLTG--ASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L LLTG ++R +A + + + R + + + AE G+E Sbjct: 2 GFLDGKRILLTGLLSNRSIAYGIAKACKREGAELAFTYVGDRFKDRITEFAAEFGSE--- 58 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLG--DVSKGFVDLSDST 118 + P D+ +A + L +L+ L L+++ G ++ F+D Sbjct: 59 ---LVFPCDVADDAQIDALFASLKT--HWDSLDG--LVHSIGFAPREAIAGDFLDGLTRE 111 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 ++ S L + L D + +++ +S L A + + KAA + Sbjct: 112 NFRIAHDISAYSFPALAKAALPMLSD----DASLLTLSYLGAERAIPNYNTMGLAKAALE 167 Query: 179 MLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKV 236 + LA L VRV + GP+ T + ++ + ++ + V + Sbjct: 168 ASVRYLAVSLGAKGVRVNAISAGPIKT-LAASGIKSFGK--ILDFVESNSPLKRNVTIEQ 224 Query: 237 SAQKLLSLLEK 247 LL Sbjct: 225 VGNAGAFLLSD 235 >3UCF-A nrPDB Length = 223 Score = 70.1 bits (170), Expect = 9e-13, Method: Composition-based stats. Identities = 44/254 (17%), Positives = 79/254 (31%), Gaps = 41/254 (16%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 G + V ++ G + G G LA L S + +V A L Sbjct: 3 GSDKTVYVVLGGTSGIGAELAKQLESEHT----IVHVASRQTGL---------------- 42 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 D+ E + + LI AGS G V + TQ Sbjct: 43 -----DISDEKSVYHYFETIGAFDH--------LIVTAGSY--APAGKVVDVEVTQAKYA 87 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQV 183 + + + ++ S + + + + A AA + +V Sbjct: 88 FDTKFWGAVLAAKHGARYLKQ----GGSITLTSGMLSRKVVANTYVKAAINAAIEATTKV 143 Query: 184 LALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLS 243 LA E +RV +PG T+ + D ++ Q GK+ + A L Sbjct: 144 LAKELAPIRVNAISPGLTKTEAYKGMNADDRDAMYQRT-QSHLPVGKVGEASDIAMAYLF 202 Query: 244 LLEKDEFKSGAHVD 257 ++ + + +G +D Sbjct: 203 AIQ-NSYMTGTVID 215 >5KOI-A nrPDB Length = 293 Score = 70.1 bits (170), Expect = 1e-12, Method: Composition-based stats. Identities = 46/265 (17%), Positives = 98/265 (36%), Gaps = 21/265 (7%) Query: 1 MEGGLGRAVCLLTGASR--GFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER 58 MEG + L+ G + +A LA + G+ L + + D ++++ AE+ Sbjct: 22 MEGLMQGKRGLIMGVANNHSLAWGIAKQLA---AQGAELAFTYQGDALGKRVKPL--AEQ 76 Query: 59 SGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST 118 G V +P D+ A + + + + + GL L++ G D ++ +D T Sbjct: 77 VGSDFV-LPCDVEDIATVDAVFEEIEK--KWGGLD--FLVHAIG-FSDKTELKGRYADVT 130 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 N+ + S T +A +++ ++ + + + + KAA + Sbjct: 131 TRENFSRTMVISAYSFTEVAQRA-EKLMKDGGSILTLTYGGSTRTIPNYNVMGVAKAALE 189 Query: 179 MLFQVLALE--EPNVRVLNYAPGPLDT-DMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235 + + LA + +RV + GP+ T + ++ R+ + VD Sbjct: 190 AMVRYLAADYGPQGIRVNAISAGPVRTLAGAGIGDARAIFSYQRRN----SPLRRTVDID 245 Query: 236 VSAQKLLSLLEKDEFKSGAHVDFYD 260 + + LL + F D Sbjct: 246 DVGKSAVYLLSDLSSGVTGEIHFVD 270 >4NR0-A nrPDB Length = 273 Score = 68.5 bits (166), Expect = 2e-12, Method: Composition-based stats. Identities = 40/251 (15%), Positives = 88/251 (35%), Gaps = 20/251 (7%) Query: 3 GGLGRAVCLLTGASR--GFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+ G + +A A++ G+ L + +N + LR E + Sbjct: 2 GFLTGKRALIVGVASKLSIASGIA---AAMHREGAELAFTYQN-DKLRGRVEEFASGWGS 57 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVS--KGFVDLSDST 118 + P D+ ++ ++ + AL + GL +++++ G F ++ Sbjct: 58 RPELCFPCDVADDSQIEAVFAALGK--HWDGLD--IIVHSVGFAPGDQLDGDFTAVTTRE 113 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 ++ S + L + + G N +++ +S L A + + + KA+ + Sbjct: 114 GFRIAHDISAYSFIALAKAGREMM---KGRNGSLLTLSYLGAERTMPNYNVMGMAKASLE 170 Query: 179 MLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKV 236 + LA L RV + GP+ T + ++ M + + V + Sbjct: 171 AGVRYLAGSLGAEGTRVNAVSAGPIRT-LAASGIKSFRK--MLAANERQTPLRRNVTIEE 227 Query: 237 SAQKLLSLLEK 247 L Sbjct: 228 VGNAGAFLCSD 238 >4ZJU-A nrPDB Length = 275 Score = 65.8 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 41/249 (16%), Positives = 91/249 (36%), Gaps = 22/249 (8%) Query: 2 EGGLGRAVCLLTGASR--GFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS 59 +G L L+ G + +A L G+ L + N E L++ E AE+ Sbjct: 11 QGLLAGKRFLIAGVASKLSIAYGIAQALHR---EGAELAFTYPN-EKLKKRVDEF-AEQF 65 Query: 60 GLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVS--KGFVDLSDS 117 G ++V P D+ +A + L + G+ ++++ G + F D++D Sbjct: 66 GSKLV-FPCDVAVDAEIDNAFAELAK--HWDGVDG--VVHSIGFAPAHTLDGDFTDVTDR 120 Query: 118 TQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAAR 177 ++ S + + + G ++ ++ + + + + KA+ Sbjct: 121 DGFKIAHDISAYSFVAMARAAKPLLQARQGC---LLTLTYQGSERVMPNYNVMGMAKASL 177 Query: 178 DMLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235 + + LA L +RV + GP+ T + ++ M +++ + V + Sbjct: 178 EAGVRYLASSLGVDGIRVNAISAGPIRT-LAASGIKSFRK--MLDANEKVAPLKRNVTIE 234 Query: 236 VSAQKLLSL 244 L L Sbjct: 235 EVGNAALFL 243 >5TF4-A nrPDB Length = 274 Score = 65.5 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 36/186 (19%), Positives = 77/186 (41%), Gaps = 13/186 (6%) Query: 21 RTLAPLLAS-LLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQL 79 R++A +A S G+ L + + EA+++ L E G V D+ A + + Sbjct: 24 RSIAWGIAKTASSAGAELAFTYQ-GEAMKKRVEPLAEEVKGF--VCGHCDVSDSASIDAV 80 Query: 80 LGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVL 139 + + + L L++ G D + D ++ N +N+ S+ LT ++ Sbjct: 81 FNTIEK--KWGKLD--FLVHAIG-FSDKEELSGRYVDISESNFMMTMNI-SVYSLT-ALT 133 Query: 140 KAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYA 197 K +++ ++ A + + + KAA + + LA++ ++RV + Sbjct: 134 KRAEKLMSDGGSILTLTYYGAEKVVPNYNVMGVAKAALEASVKYLAVDLGPKHIRVNAIS 193 Query: 198 PGPLDT 203 GP+ T Sbjct: 194 AGPIKT 199 >3GRK-A nrPDB Length = 293 Score = 65.1 bits (157), Expect = 3e-11, Method: Composition-based stats. Identities = 38/205 (18%), Positives = 75/205 (36%), Gaps = 17/205 (8%) Query: 3 GGLGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+ G + R +A + + + + L ELGA +G Sbjct: 27 GLLQGKRGLILGVANNRSIAWGIAKAAREAGAELAFTYQGDALKKRVEPLAEELGAFVAG 86 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 D+ A + + L + + L L++ G D + D+++ Sbjct: 87 ------HCDVADAASIDAVFETLEK--KWGKLD--FLVHAIG-FSDKDELTGRYIDTSEA 135 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 N L S+ LT +V + +++ ++ A + + + KAA + Sbjct: 136 NFT-NTMLISVYSLT-AVSRRAEKLMADGGSILTLTYYGAEKVMPNYNVMGVAKAALEAS 193 Query: 181 FQVLALE--EPNVRVLNYAPGPLDT 203 + LA++ N+RV + GP+ T Sbjct: 194 VKYLAVDLGPQNIRVNAISAGPIKT 218 >3SLK-A nrPDB Length = 795 Score = 63.9 bits (154), Expect = 6e-11, Method: Composition-based stats. Identities = 41/217 (18%), Positives = 74/217 (34%), Gaps = 21/217 (9%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSAR--NDEALRQLEAELGAERSGLRVVRV 66 L+TG + G +A L +++++S R +L A+L A G V Sbjct: 532 TVLVTGGTGALGAEVARHLVIERGVRNLVLVSRRGPAASGAAELVAQLTA--YGAEVSLQ 589 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ L ++L ++ P +++ AG L D + + +++ Sbjct: 590 ACDVADRETLAKVLASI-----PDEHPLTAVVHAAGVLDDGVSESLTV---ERLDQVLRP 641 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLAL 186 + + + + +V SS+ + G Y A + D L Q Sbjct: 642 KVDG--------ARNLLELIDPDVALVLFSSVSGVLGSGGQGNYAAANSFLDALAQQRQS 693 Query: 187 EEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQ 223 R L + P + M RE D R GL Sbjct: 694 RGLPTRSLAWGP-WAEHGMASTLREAEQDRLARSGLL 729 >3U9L-A nrPDB Length = 324 Score = 63.5 bits (153), Expect = 8e-11, Method: Composition-based stats. Identities = 46/236 (19%), Positives = 80/236 (33%), Gaps = 20/236 (8%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLV-----LSARNDEALRQLEAELGAERS 59 + + + L+TGAS GFGR A LA G + + RN + + Sbjct: 3 MSKKIILITGASSGFGRLTAEALAG---AGHRVYASMRDIVGRNASNVEAIAGFARDNDV 59 Query: 60 GLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQ 119 LR + + D+ ++ + + + + + + +LI+NAG + Q Sbjct: 60 DLRTLEL--DVQSQVSVDRAIDQI--IGEDGRID--VLIHNAGHMVFGPAEAFT---PEQ 110 Query: 120 VNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDM 179 + +N+ S + + L ++ SS P A Y A KAA D Sbjct: 111 FAELYDINVLSTQRVNRAALPHMRRQKHGLLIWISSSSSAGGTP-PYLAPYFAAKAAMDA 169 Query: 180 LFQVLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVD 233 + A E + PG + A D R+ E L + Sbjct: 170 IAVQYARELSRWGIETSIIVPGAFTSGTNHFAHSGVPDDHARQAEYEAGPNAGLGE 225 >4ALL-A nrPDB Length = 277 Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 42/248 (16%), Positives = 89/248 (35%), Gaps = 20/248 (8%) Query: 5 LGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 L ++ G + R +A +L L G+ LV + R + + ++LE L Sbjct: 25 LENKTYVIMGIANKRSIAFGVAKVLDQL---GAKLVFTYRKERSRKELEKLLEQLNQP-E 80 Query: 63 VVRVPADLGAEAGLQQLLGALRE-LPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVN 121 D+ ++ + + + + G+ + N + D+ F + S Sbjct: 81 AHLYQIDVQSDEEVINGFEQIGKDVGNIDGVYHSIAFAN---MEDLRGRFSETSREG-FL 136 Query: 122 NYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLF 181 ++ S+ + K P+ ++V + L + + + KA+ + Sbjct: 137 LAQDISSYSLTIVAHEAKKLMPE----GGSIVATTYLGGEFAVQNYNVMGVAKASLEANV 192 Query: 182 QVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQ 239 + LAL+ N+RV + GP+ T A+ + K ++E + VD + Sbjct: 193 KYLALDLGPDNIRVNAISAGPIRT---LSAKGVGGFNTILKEIEERAPLKRNVDQVEVGK 249 Query: 240 KLLSLLEK 247 LL Sbjct: 250 TAAYLLSD 257 >2DKN-A nrPDB Length = 255 Score = 63.1 bits (152), Expect = 1e-10, Method: Composition-based stats. Identities = 52/266 (19%), Positives = 86/266 (32%), Gaps = 69/266 (25%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 V +TG++ G G L LLA G ++ R + A Sbjct: 3 VIAITGSASGIGAALKELLAR---AGHTVIGIDRGQAD-------------------IEA 40 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 DL G + + A+ L R G+ L+ AG + + A+N Sbjct: 41 DLSTPGGRETAVAAV--LDRCGGVLDG-LVCCAGVGVTAANSGL----------VVAVNY 87 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFK----------------------- 165 + L + +A S G V + S+ A QP Sbjct: 88 FGVSALLDGLAEAL--SRGQQPAAVIVGSIAATQPGAAELPMVEAMLAGDEARAIELAEQ 145 Query: 166 -GWAL--YCAGKAARDMLFQ--VLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRK 220 G Y K A L + V+ VR+ APG ++T + Q ++ DP + Sbjct: 146 QGQTHLAYAGSKYAVTCLARRNVVDWAGRGVRLNVVAPGAVETPLLQASK---ADPRYGE 202 Query: 221 GLQELK-AKGKLVDCKVSAQKLLSLL 245 + G+ + + A+ + LL Sbjct: 203 STRRFVAPLGRGSEPREVAEAIAFLL 228 >3K2E-A nrPDB Length = 296 Score = 60.4 bits (145), Expect = 7e-10, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 68/186 (36%), Gaps = 19/186 (10%) Query: 22 TLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLG 81 +A + + + ++ LS + + L LG + + VP D+ + + Sbjct: 47 GIAKAVCAQGAEVALTYLSETFKKRVDPLAESLGVK------LTVPCDVSDAESVDNMFK 100 Query: 82 ALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST--QVNNYWALNLTSMLCLTSSVL 139 L E L + +A + D ++ D++ ++ S + S Sbjct: 101 VLAE-----EWGSLDFVVHAVAFSDKNELKGRYVDTSLGNFLTSMHISCYSFTYIASKAE 155 Query: 140 KAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE--EPNVRVLNYA 197 + +++ +S A + + + KAA + + LA++ + +RV + Sbjct: 156 PLMTN----GGSILTLSYYGAEKVVPHYNVMGVCKAALEASVKYLAVDLGKQQIRVNAIS 211 Query: 198 PGPLDT 203 GP+ T Sbjct: 212 AGPVRT 217 >5CFZ-A nrPDB Length = 305 Score = 59.7 bits (143), Expect = 1e-09, Method: Composition-based stats. Identities = 32/252 (12%), Positives = 83/252 (32%), Gaps = 25/252 (9%) Query: 3 GGLGRAVCLLTGASR--GFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+TG + +A + + + + + + + A+LG++ Sbjct: 45 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD--- 101 Query: 61 LRVVRVPADLGAEAGLQQLLGALREL-PRPKGLQRLLLINNAGSLGDVS--KGFVDLSDS 117 + + D+ +A + + L ++ P+ G +++ G +V+ Sbjct: 102 ---IVLQCDVAEDASIDTMFAELGKVWPKFDG-----FVHSIGFAPGDQLDGDYVNAVTR 153 Query: 118 TQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAAR 177 ++ S + + + ++ +S L A + + + KA+ Sbjct: 154 EGFKIAHDISSYSFVAMAKACRSML----NPGSALLTLSYLGAERAIPNYNVMGLAKASL 209 Query: 178 DMLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235 + + +A + VRV + GP+ T + + M + + + V + Sbjct: 210 EANVRYMANAMGPEGVRVNAISAGPIRT-LAASGIKDFRK--MLAHCEAVTPIRRTVTIE 266 Query: 236 VSAQKLLSLLEK 247 L Sbjct: 267 DVGNSAAFLCSD 278 >4JQC-A nrPDB Length = 282 Score = 59.3 bits (142), Expect = 2e-09, Method: Composition-based stats. Identities = 32/252 (12%), Positives = 83/252 (32%), Gaps = 25/252 (9%) Query: 3 GGLGRAVCLLTGASR--GFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+TG + +A + + + + + + + A+LG++ Sbjct: 22 GFLSGKRILVTGVASKLSIAYGIAQAMHREGAELAFTYQNDKLKGRVEEFAAQLGSD--- 78 Query: 61 LRVVRVPADLGAEAGLQQLLGALREL-PRPKGLQRLLLINNAGSLGDVS--KGFVDLSDS 117 + + D+ +A + + L ++ P+ G +++ G +V+ Sbjct: 79 ---IVLQCDVAEDASIDTMFAELGKVWPKFDG-----FVHSIGFAPGDQLDGDYVNAVTR 130 Query: 118 TQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAAR 177 ++ S + + + ++ +S L A + + + KA+ Sbjct: 131 EGFKIAHDISSYSFVAMAKACRSML----NPGSALLTLSYLGAERAIPNYNVMGLAKASL 186 Query: 178 DMLFQVLA--LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235 + + +A + VRV + GP+ T ++ M + + + V + Sbjct: 187 EANVRYMANAMGPEGVRVNAISAGPIRTLAASGIKDFRK---MLAHCEAVTPIRRTVTIE 243 Query: 236 VSAQKLLSLLEK 247 L Sbjct: 244 DVGNSAAFLCSD 255 >4J3F-A nrPDB Length = 280 Score = 58.1 bits (139), Expect = 3e-09, Method: Composition-based stats. Identities = 40/259 (15%), Positives = 91/259 (35%), Gaps = 16/259 (6%) Query: 3 GGLGRAVCLLTG--ASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+TG +++ +A + + + + + + + +L AE Sbjct: 22 GFLAGKKILITGLLSNKSIAYGIAKAMHREGAELAFTYV-GQFKDRVEKLCAEFNP---- 76 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 +P D+ ++ ++ L L ++ GL ++ + F+D Sbjct: 77 --AAVLPCDVISDQEIKDLFVELGKV--WDGLDAIVHSIAFAPRDQLEGNFIDCVTREGF 132 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 + ++ S L ++ + N ++V ++ + A + + KA+ + Sbjct: 133 SIAHDISAYSFAALAKEG-RSMMKNR--NASMVALTYIGAEKAMPSYNTMGVAKASLEAT 189 Query: 181 FQ--VLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSA 238 + LAL E ++V + GP+ T D + LK +++ + Sbjct: 190 VRYTALALGEDGIKVNAVSAGPIKTLAASGISNFKKMLDYNAMVSPLKKNVDIMEVGNTV 249 Query: 239 QKLLSLLEKDEFKSGAHVD 257 L S + HVD Sbjct: 250 AFLCSDMATGITGEVVHVD 268 >4NK4-A nrPDB Length = 301 Score = 55.8 bits (133), Expect = 2e-08, Method: Composition-based stats. Identities = 39/246 (15%), Positives = 85/246 (34%), Gaps = 20/246 (8%) Query: 5 LGRAVCLLTGASR--GFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 L L+ G + +A +L S G+ L S + + ++L+ S Sbjct: 39 LKGKRGLIMGVANDHSIAWGIAKVLHS---AGAQLAFSYQGESIGKRLKPLALTVDSDFM 95 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 +P ++ + + L ++E R + L ++++ +T +N Sbjct: 96 ---IPCNVEDPSSMDLLFERIKE--RWETLD--FVVHS--IAFSDKNELRGPYYNTSRDN 146 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQ 182 + L S T V +A ++ ++ +++ + K+A + + Sbjct: 147 FIQTMLVSCFSFTEIVRRA-AQLMPHGGAMITLTYGGSMRVVPNYNAMAPAKSALESSTK 205 Query: 183 VLALEEP--NVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQK 240 LA + N+R+ + GP+ T S D+ +E + V + Sbjct: 206 YLACDYGGMNIRINAISAGPVRT---LAGASISNGRDIAAWSKENSPLKRTVSLEDIGNS 262 Query: 241 LLSLLE 246 L LL Sbjct: 263 ALYLLS 268 >1FJH-A nrPDB Length = 257 Score = 53.1 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 46/269 (17%), Positives = 78/269 (28%), Gaps = 71/269 (26%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 + +++G + G G +L + ++ + R+ E V A Sbjct: 3 IIVISGCATGIGAATRKVL--EAAGHQIVGIDIRDAE--------------------VIA 40 Query: 69 DLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNL 128 DL G +Q + + KG+ L+L G V ++N Sbjct: 41 DLSTAEGRKQAIADVL-AKCSKGMDGLVLCAGLGPQTKVLGN------------VVSVNY 87 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLC----ALQPFK------------------- 165 L + L A G V ISS+ A Sbjct: 88 FGATELMDAFLPALKK--GHQPAAVVISSVASAHLAFDKNPLALALEAGEEAKARAIVEH 145 Query: 166 -----GWALYCAGKAARDMLFQ--VLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDM 218 G Y K A + + A E VR+ APG +T + Q DP Sbjct: 146 AGEQGGNLAYAGSKNALTVAVRKRAAAWGEAGVRLNTIAPGATETPLLQAGL---QDPRY 202 Query: 219 RKGLQELK-AKGKLVDCKVSAQKLLSLLE 246 + + + G+ + A + L+ Sbjct: 203 GESIAKFVPPMGRRAEPSEMASVIAFLMS 231 >2PD3-A nrPDB Length = 275 Score = 52.4 bits (124), Expect = 2e-07, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 86/205 (41%), Gaps = 17/205 (8%) Query: 3 GGLGRAVCLLTGAS--RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L+ G + + +A S + G+ L + N E+L + + E + Sbjct: 2 GFLKGKKGLIVGVANNKSIAYGIAQ---SCFNQGATLAFTYLN-ESLEKRVRPIAQELN- 56 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQV 120 D+ E + L +++ + G ++ + A + + +G + + + Sbjct: 57 -SPYVYELDVSKEEHFKSLYNSVK---KDLGSLDFIVHSVAFAPKEALEGSLLETSKSAF 112 Query: 121 NNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDML 180 N +++ S++ LT+++ + +V+ +S L + + + + KAA + Sbjct: 113 NTAMEISVYSLIELTNTLKPLLNN----GASVLTLSYLGSTKYMAHYNVMGLAKAALESA 168 Query: 181 FQVLALE--EPNVRVLNYAPGPLDT 203 + LA++ + ++RV + GP+ T Sbjct: 169 VRYLAVDLGKHHIRVNALSAGPIRT 193 >2O2S-A nrPDB Length = 315 Score = 51.6 bits (122), Expect = 3e-07, Method: Composition-based stats. Identities = 46/275 (16%), Positives = 91/275 (33%), Gaps = 39/275 (14%) Query: 5 LGRAVCLLTGA--SRGFGRTLAPLLASLLSPGS------VLVLSARNDEALRQLEAELGA 56 L + G S G+G +A LAS + + VL L ++ ++ R E Sbjct: 7 LRGQTAFVAGVADSHGYGWAIAKHLASAGARVALGTWPPVLGLFQKSLQSGRLDEDRKLP 66 Query: 57 ERSGLRVVRV---PADLGAEAGLQQLLGALRELPRPKGL--------------QRLLLIN 99 + S + V A + Q + + G +L++ Sbjct: 67 DGSLIEFAGVYPLDAAFDKPEDVPQDIKDNKRYAGVDGYTIKEVAVKVKQDLGNIDILVH 126 Query: 100 NAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLC 159 + + +V+K ++ S + + S + L + + V +S L Sbjct: 127 SLANGPEVTKPLLETSRKGYLAASSN-SAYSFVSLLQHFGPIMNE----GGSAVTLSYLA 181 Query: 160 ALQPFKGWAL-YCAGKAARDMLFQVLALE---EPNVRVLNYAPGPLD----TDMQQLARE 211 A + G+ + KAA + + LA E + VRV + GPL + + + + Sbjct: 182 AERVVPGYGGGMSSAKAALESDTRTLAWEAGQKYGVRVNAISAGPLKSRAASAIGKSGEK 241 Query: 212 TSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLE 246 + +D + + + L LL Sbjct: 242 SFIDYAIDYSYNN-APLRRDLHSDDVGGAALFLLS 275 >4Q9N-A nrPDB Length = 298 Score = 50.8 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 40/275 (14%), Positives = 93/275 (33%), Gaps = 37/275 (13%) Query: 1 MEGGLGRAVCLLTGASR--GFGRTLAPLLASLLSP---GSVLVLSARNDEALRQLEAELG 55 ++ L + + G G+G +A +LA + G+ + + ++L + Sbjct: 2 LKIDLTGKIAFIAGIGDDNGYGWGIAKMLAEAGATILVGTWVPIYKIFSQSLELGKFNAS 61 Query: 56 AERSGLRVVRVP------ADLGAEAGLQQ--------------LLGALRELPRPKGLQRL 95 E S ++ A + Q + + E + Sbjct: 62 RELSNGELLTFAKIYPMDASFDTPEDIPQEILENKRYKDLSGYTVSEVVEQVKKHFGHID 121 Query: 96 LLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNI 155 +L+++ + +++K +D S + + + S + L S + +++ Sbjct: 122 ILVHSLANSPEIAKPLLDTSRKGYLAA-LSTSSYSFISLLSHFGPIM----NAGASTISL 176 Query: 156 SSLCALQPFKGWAL-YCAGKAARDMLFQVLALEEP---NVRVLNYAPGPLDTDMQQLARE 211 + L +++ G+ A KAA + +VLA E VRV + GPL + + + Sbjct: 177 TYLASMRAVPGYGGGMNAAKAALESDTKVLAWEAGRRWGVRVNTISAGPLAS---RAGKA 233 Query: 212 TSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLE 246 M Q+ ++ + L+ Sbjct: 234 IGFIERMVDYYQDWAPLPSPMEAEQVGAAAAFLVS 268 >4OYR-A nrPDB Length = 289 Score = 45.0 bits (105), Expect = 3e-05, Method: Composition-based stats. Identities = 44/264 (16%), Positives = 88/264 (33%), Gaps = 33/264 (12%) Query: 1 MEGGLGRAVCLLTG--ASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAER 58 M G L L++G +A + G+ LVL+ + L Q + R Sbjct: 21 MTGLLDGKRILVSGIITDSSIAFHIARV---AQEQGAQLVLTGFDRLRLIQRITD----R 73 Query: 59 SGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDS- 117 + + D+ E L L G + E + +++ G + G D+ Sbjct: 74 LPAKAPLLELDVQNEEHLASLAGRVTEAIGAGNKLDGV-VHSIGFMPQTGMGINPFFDAP 132 Query: 118 -TQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYC---AG 173 V+ ++ S + ++L ++V + P + Y Sbjct: 133 YADVSKGIHISAYSYASMAKALLPIM----NPGGSIVGMD----FDPSRAMPAYNWMTVA 184 Query: 174 KAARDMLFQVLALE--EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQ-------E 224 K+A + + + +A E + VR A GP+ T ++ + +Q + Sbjct: 185 KSALESVNRFVAREAGKYGVRSNLVAAGPIRTLAMSAIVGGALGEEAGAQIQLLEEGWDQ 244 Query: 225 LKAKG-KLVDCKVSAQKLLSLLEK 247 G + D A+ + +LL Sbjct: 245 RAPIGWNMKDATPVAKTVCALLSD 268 >3F4B-A nrPDB Length = 323 Score = 44.7 bits (104), Expect = 4e-05, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 54/128 (42%), Gaps = 9/128 (7%) Query: 80 LGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVL 139 + + L K + +L+++ + +V K +D S ++ + S++ L Sbjct: 107 IEEVANLIYNKYGKISMLVHSLANGREVQKSLLDTSRDGYLDAISKSSY-SLISLCKHFC 165 Query: 140 KAFPDSPGLNRTVVNISSLCALQPFKGWAL-YCAGKAARDMLFQVLAL---EEPNVRVLN 195 K +VV+++ + + G+ + KAA + +VLA + N+R+ Sbjct: 166 KFM----NSGGSVVSLTYQASQKVVPGYGGGMSSAKAALESDTRVLAYYLGRKYNIRINT 221 Query: 196 YAPGPLDT 203 + GPL + Sbjct: 222 ISAGPLKS 229 >1ENP-A nrPDB Length = 312 Score = 43.9 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 65/185 (35%), Gaps = 12/185 (6%) Query: 66 VPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 V A+ + E R +L+++ + +VSK ++ S + A Sbjct: 102 VKANKRYAGSSNWTVQEAAECVRQDFGSIDILVHSLANGPEVSKPLLETSRKGYLAAISA 161 Query: 126 LNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWAL-YCAGKAARDMLFQVL 184 + + + L+ L ++++ + + + G+ + KAA + +VL Sbjct: 162 SSYSFVSLLSH-FLPIM----NPGGASISLTYIASERIIPGYGGGMSSAKAALESDTRVL 216 Query: 185 ALE---EPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKL 241 A E + N+RV + GPL + + A+ M + K + Sbjct: 217 AFEAGRKQNIRVNTISAGPLGS---RAAKAIGFIDTMIEYSYNNAPIQKTLTADEVGNAA 273 Query: 242 LSLLE 246 L+ Sbjct: 274 AFLVS 278 >2PTG-A nrPDB Length = 319 Score = 43.5 bits (101), Expect = 9e-05, Method: Composition-based stats. Identities = 29/176 (16%), Positives = 66/176 (37%), Gaps = 14/176 (7%) Query: 79 LLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSV 138 + + E R Q +L+++ + +V+K + S + + + + + L Sbjct: 119 TISEVAEAVRADVGQIDILVHSLANGPEVTKPLLQTSRKGYLAAVSSSSYSFVSLL-QHF 177 Query: 139 LKAFPDSPGLNRTVVNISSLCALQPFKGWAL-YCAGKAARDMLFQVLALE---EPNVRVL 194 L + + + +S + + + G+ + KAA + + LA E VRV Sbjct: 178 LPLMKE----GGSALALSYIASEKVIPGYGGGMSSAKAALESDCRTLAFEAGRARAVRVN 233 Query: 195 NYAPGPLD----TDMQQLARETSVDPDMRKGLQELKAKGKLVDCKVSAQKLLSLLE 246 + GPL + + + +T +D + + K ++ + L LL Sbjct: 234 CISAGPLKSRAASAIGKAGDKTFIDLAI-DYSEANAPLQKELESDDVGRAALFLLS 288 >4LIS-A nrPDB Length = 371 Score = 42.3 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 30/151 (19%), Positives = 55/151 (36%), Gaps = 31/151 (20%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLV---LSARNDEALRQLEAELGAERSGLRVVRV 66 L+TG + G LA L + V+V L + EAL ++E SG + Sbjct: 6 VLVTGGTGYIGSFT--TLALLEAGYKVVVADNLYNSSAEALNRIELI-----SGKKAEFA 58 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ EA ++ A ++ L + +G + +Y+ + Sbjct: 59 QLDVTDEAAFDKVFEAHPDIDSVIHFAALKAVGESG---------------EKPLDYYHV 103 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTVVNISS 157 N+ +CL S+++ +V SS Sbjct: 104 NVYGTICLLRSMVRHNVT------NIVFSSS 128 >2NTV-A nrPDB Length = 268 Score = 40.8 bits (94), Expect = 6e-04, Method: Composition-based stats. Identities = 34/207 (16%), Positives = 75/207 (36%), Gaps = 19/207 (9%) Query: 3 GGLGRAVCLLTG--ASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSG 60 G L L++G +A + G+ LVL+ + L Q A+ +++ Sbjct: 2 GLLEGKRILVSGIITDSSIAFHIAKV---AQEAGAQLVLTGFDRLRLIQRIADRLPDKAP 58 Query: 61 LRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDS--T 118 L + V + +++ + E + G+ +++ G + G D+ Sbjct: 59 LIELDVQNEEHLATLAERVTAEIGEGNKLDGV-----VHSIGFMPQTGMGTNQFFDAPYE 113 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 V+ ++ S L ++L ++V + + + K+A + Sbjct: 114 DVSKGIHISTYSYASLAKALLLIM----NSGGSIVGM-DFDPTRAMPAYNWMTVAKSALE 168 Query: 179 MLFQVLALE--EPNVRVLNYAPGPLDT 203 + + +A E + VR A GP+ T Sbjct: 169 SVNRFVAREAGKYGVRSNLVAAGPIRT 195 >3RFT-A nrPDB Length = 267 Score = 40.4 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 30/208 (14%), Positives = 52/208 (25%), Gaps = 66/208 (31%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TGA+ GR + LA + + +L + +G V DL Sbjct: 7 LVTGAAGQLGRVMRERLAPMAE--------------ILRLADLSPLDPAGPNEECVQCDL 52 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 + ++ + G +S N+ Sbjct: 53 ADANAVNAMVAGCDGIVHLGG----------------------ISVEKPFEQILQGNIIG 90 Query: 131 MLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGW------------ALYCAGKAARD 178 + L +A +V SS + + LY K Sbjct: 91 LYNL-YEAARAHGQPR-----IVFASSNHTIGYYPQTERLGPDVPARPDGLYGVSKC--- 141 Query: 179 MLFQVLAL--------EEPNVRVLNYAP 198 + LA E VR+ + P Sbjct: 142 -FGENLARMYFDKFGQETALVRIGSCTP 168 >3SXP-A nrPDB Length = 362 Score = 40.4 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 35/218 (16%), Positives = 53/218 (24%), Gaps = 49/218 (22%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEAL----RQLEAELGA 56 ++ L L+TG + G LA V+VL L R Sbjct: 4 IDDELENQTILITGGAGFVGSNLAFHFQENHPKAKVVVLDKFRSNTLFSNNRPSSLGHFK 63 Query: 57 ERSGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSD 116 G + + AD+ L++L + L L + A Sbjct: 64 NLIGFKGEVIAADINNPLDLRRL----------EKLHFDYLFHQAAVSDTTMLNQ----- 108 Query: 117 STQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWAL------- 169 N + L + V+ SS + Sbjct: 109 ----ELVMKTNY-------QAFLNLLEIARSKKAKVIYASS-AGVYGNTKAPNVVGKNES 156 Query: 170 ----YCAGKAARDMLFQVLALEEPNVRV-----LNYAP 198 Y K D VL+ NV+V Y P Sbjct: 157 PENVYGFSKLCMDEF--VLSHSNDNVQVGLRYFNVYGP 192 >1OOE-A nrPDB Length = 236 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 31/203 (15%), Positives = 54/203 (26%), Gaps = 27/203 (13%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 ++ G G + G ++ +L A + V + Sbjct: 6 VIVYGGKGALGSAILEFFKK---NGYTVLNI------------DLSANDQADSNILVDGN 50 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 Q +L + + + + AG S D + L + Sbjct: 51 KNWTEQEQSILEQTASSLQGSQVDGVFCV--AGGWAGGSASSKDFVKNAD------LMIK 102 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE-- 187 + ++ K + + A+ P Y KAA L LA + Sbjct: 103 QSVWSSAIAAKLATTHLKPGGLLQLTGAAAAMGPTPSMIGYGMAKAAVHHLTSSLAAKDS 162 Query: 188 --EPNVRVLNYAPGPLDTDMQQL 208 N VL P LDT M + Sbjct: 163 GLPDNSAVLTIMPVTLDTPMNRK 185 >2O2Y-A nrPDB Length = 349 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 20/129 (15%), Positives = 53/129 (41%), Gaps = 9/129 (6%) Query: 79 LLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSV 138 + + L K + +L+++ + +V K ++ S ++ + S++ L Sbjct: 111 TIEDVANLIHQKYGKINMLVHSLANAKEVQKDLLNTSRKGYLDALSKSSY-SLISLCKYF 169 Query: 139 LKAFPDSPGLNRTVVNISSLCALQPFKGWAL-YCAGKAARDMLFQVLAL---EEPNVRVL 194 + ++++++ + + G+ + KAA + +VLA N+R+ Sbjct: 170 VNIMKPQ----SSIISLTYHASQKVVPGYGGGMSSAKAALESDTRVLAYHLGRNYNIRIN 225 Query: 195 NYAPGPLDT 203 + GPL + Sbjct: 226 TISAGPLKS 234 >1DIR-A nrPDB Length = 241 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 28/194 (14%), Positives = 54/194 (27%), Gaps = 13/194 (6%) Query: 24 APLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGAEAGLQQLLGAL 83 + + GS V + R + E + V+ D Q+ + Sbjct: 10 VLVYGGRGALGSRCVQAFRARNWWVASIDVVENEEASASVIVKMTD-SFTEQADQVTAEV 68 Query: 84 RELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFP 143 +L + + +L + AG + L + + + ++ Sbjct: 69 GKLLGDQKVDAILCV--AGGWAGGNAKSKSLFKNCDLMW------KQSIWTSTISSHLAT 120 Query: 144 DSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE----EPNVRVLNYAPG 199 + + AL G Y K A L Q LA + + P Sbjct: 121 KHLKEGGLLTLAGAKAALDGTPGMIGYGMAKGAVHQLCQSLAGKNSGMPSGAAAIAVLPV 180 Query: 200 PLDTDMQQLARETS 213 LDT M + + + Sbjct: 181 TLDTPMNRKSMPEA 194 >2HUN-A nrPDB Length = 336 Score = 39.6 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 32/203 (15%), Positives = 59/203 (29%), Gaps = 40/203 (19%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVL----VLSARNDEALRQLEAELGAERSGLRVVRV 66 L+TG G + V+ + N L+ LE + R V Sbjct: 7 LVTGGMGFIGSNFIRYILEKHPDWEVINIDKLGYGSNPANLKDLEDD-------PRYTFV 59 Query: 67 PADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWAL 126 D+ +++L+ + G + ++ VD S + + Sbjct: 60 KGDVADYELVKELVRKVD-----------------GVVHLAAESHVDRS-ISSPEIFLHS 101 Query: 127 NLTSMLCLTSSVLKAFPDSPGLNRTV------VNISSLCALQPFKGWALYCAGKAA---- 176 N+ L S+ + P+ ++ + + S + Y A KAA Sbjct: 102 NVIGTYTLLESIRRENPEVRFVHVSTDEVYGDILKGSFTENDRLMPSSPYSATKAASDML 161 Query: 177 RDMLFQVLALEEPNVRV-LNYAP 198 + L R NY P Sbjct: 162 VLGWTRTYNLNASITRCTNNYGP 184 >1KEU-A nrPDB Length = 361 Score = 39.3 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 55/185 (29%), Gaps = 20/185 (10%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLV---LSARNDEALRQLEAELGAERSGLRVVRVP 67 L+TG + G + + V + A N E+L + R Sbjct: 4 LITGGAGFIGSAVVRHIIKNTQDTVVNIDKLTYAGNLESLSDISES---NRYNFE----H 56 Query: 68 ADLGAEAGLQQLL-----GALRELPRPKGLQRLLLINNA----GSLGDVSKGFVDLSDST 118 AD+ A + ++ A+ L + R + A +G + V + Sbjct: 57 ADICDSAEITRIFEQYQPDAVMHLAAESHVDRSITGPAAFIETNIVGTYALLEVARKYWS 116 Query: 119 QVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARD 178 + N T V P + + V + + + Y A KA+ D Sbjct: 117 ALGEDKKNNFRFHHISTDEVYGDLPHPDEVENS-VTLPLFTETTAYAPSSPYSASKASSD 175 Query: 179 MLFQV 183 L + Sbjct: 176 HLVRA 180 >5K1S-A nrPDB Length = 362 Score = 38.9 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 28/68 (41%), Gaps = 3/68 (4%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVR 65 L+TGAS G G + LA L G+ ++ ++ ++ L+ E R + Sbjct: 183 AGETVLITGASGGVGLSSVQ-LARL--DGARVIAVTSSEAKVQALKEAGADEVIVSRGLD 239 Query: 66 VPADLGAE 73 +D+ Sbjct: 240 FASDVRKR 247 >4G5H-A nrPDB Length = 363 Score = 38.5 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 32/264 (12%), Positives = 83/264 (31%), Gaps = 38/264 (14%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 G + L+TG + FG + + +R+++ + ++ + + ++ Sbjct: 22 GFDDKILLITGGTGSFGNAVMKRFLDSNIKEIRIF--SRDEKK----QDDIRKKYNNSKL 75 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 D+ ++ + + + L++ + + + + + + Sbjct: 76 KFYIGDVRDSQSVETAMRDVDYVFHAAALKQ---VPSCEFFPVEAVKTNIIGTENVLQSA 132 Query: 124 WALNLTSMLCLT--SSVLK--------AFPDSPGLNRTVVNISSLCALQPFKGWALYCAG 173 N+ ++CL+ + A + + ++ NI S L + A Sbjct: 133 IHQNVKKVICLSTDKAAYPINAMGISKAMMEKVFVAKS-RNIRSEQTLICGTRYGNVMAS 191 Query: 174 KAARDMLF--QVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKL 231 + + LF ++ A E + D DM + ++ + G + Sbjct: 192 RGSVIPLFIDKIKAGEPLTIT---------DPDMTRFLMSLEDAVELVVHAFKHAETGDI 242 Query: 232 V-------DCKVSAQKLLSLLEKD 248 + A LL L E D Sbjct: 243 MVQKAPSSTVGDLATALLELFEAD 266 >4PVC-A nrPDB Length = 342 Score = 38.1 bits (87), Expect = 0.003, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 52/153 (33%), Gaps = 25/153 (16%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 ++GA+ + + LL ++ SAR+ E L G + V D Sbjct: 3 VFVSGANGFIAQHIVDLLLK---EDYKVIGSARSQEKAENLTEAFGNNPK--FSMEVVPD 57 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN-L 128 + L A + + G ++++ A S D++DS + A+N + Sbjct: 58 ISK-------LDAFDHVFQKHGKDIKIVLHTA------SPFCFDITDSERDLLIPAVNGV 104 Query: 129 TSMLCLTSSVLKAFPDSPGLNRTVVNISSLCAL 161 +L + VV SS A+ Sbjct: 105 KGILHSIKKYAADSVE------RVVLTSSYAAV 131 >2NNL-D nrPDB Length = 337 Score = 38.1 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 43/272 (15%), Positives = 78/272 (28%), Gaps = 56/272 (20%) Query: 3 GGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLR 62 G VC +TGAS G L L L G + + R+ +++++ L ++ Sbjct: 2 GSQSETVC-VTGASGFIGSWLVMRL---LERGYTVRATVRDPTNVKKVKHLLDLPKAETH 57 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 + ADL E + + G + + D N Sbjct: 58 LTLWKADLADEGSFDEAIKG-----------------CTGVFHVATPMDFESKDPE--NE 98 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWAL-----------YC 171 + ML + S A R +V SS + + +C Sbjct: 99 VIKPTIEGMLGIMKSCAAA-----KTVRRLVFTSSAGTVNIQEHQLPVYDESCWSDMEFC 153 Query: 172 AGK---AARDMLFQVLALEEP-------NVRVLNYAPG-----PLDTDMQQLARETSVDP 216 K A + + LA + N+ + P + + M T++ P Sbjct: 154 RAKKMTAWMYFVSKTLAEQAAWKYAKENNIDFITIIPTLVVGPFIMSSMPPSLI-TALSP 212 Query: 217 DMRKGLQ-ELKAKGKLVDCKVSAQKLLSLLEK 247 + +G+ V + L E Sbjct: 213 ITGNEAHYSIIRQGQFVHLDDLCNAHIYLFEN 244 >2PK3-A nrPDB Length = 321 Score = 37.7 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 38/254 (14%), Positives = 75/254 (29%), Gaps = 59/254 (23%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG + G+ LA L + ++RN+EA V + D Sbjct: 15 ALITGVAGFVGKYLANHLTEQNVE---VFGTSRNNEA------------KLPNVEMISLD 59 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + +++++ ++ +K V S ++ N+ Sbjct: 60 IMDSQRVKKVISDIKPDY---------------IFHLAAKSSVKDS-WLNKKGTFSTNVF 103 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISS-------------LCALQPFKGWALYCAGKAA 176 L + +V + D ++ I S + + + Y KA+ Sbjct: 104 GTLHVLDAVRDSNLDCR-----ILTIGSSEEYGMILPEESPVSEENQLRPMSPYGVSKAS 158 Query: 177 RDMLFQVLALEE-----PNVRVLNYAPGPLDTDMQQLARETSVDPDMRK-----GLQELK 226 ML + + PG + Q + VD +M K + L+ Sbjct: 159 VGMLARQYVKAYGMDIIHTRTFNHIGPGQSLGFVTQDFAKQIVDIEMEKQEPIIKVGNLE 218 Query: 227 AKGKLVDCKVSAQK 240 A D + Q Sbjct: 219 AVRDFTDVRDIVQA 232 >3ORF-A nrPDB Length = 251 Score = 37.3 bits (85), Expect = 0.006, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 43/140 (30%), Gaps = 10/140 (7%) Query: 73 EAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSML 132 + ++ + ++ E K ++ + AG + + S V +NL S Sbjct: 67 KDSGEEEIKSVIEKINSKSIKVDTFVCAAGGWSGGNASSDEFLKS--VKGMIDMNLYSAF 124 Query: 133 CLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGKAARDMLFQVLALE----E 188 K V + AL G Y A KAA + + LA E Sbjct: 125 ASAHIGAKLLNQ----GGLFVLTGASAALNRTSGMIAYGATKAATHHIIKDLASENGGLP 180 Query: 189 PNVRVLNYAPGPLDTDMQQL 208 L P LDT + Sbjct: 181 AGSTSLGILPVTLDTPTNRK 200 >6BWL-A nrPDB Length = 328 Score = 36.2 bits (82), Expect = 0.016, Method: Composition-based stats. Identities = 38/232 (16%), Positives = 67/232 (28%), Gaps = 31/232 (13%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEA-LRQLEAELGAERSGLRVVRVPAD 69 L+TG + GR + L +L A + A + + +L ++ + D Sbjct: 4 LVTGGAGFIGRWVVKRLLQDKHEVWILDNLANSTTANITEFAHDLNLKQC------IQGD 57 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + + + QL NN+ L +++ DS N T Sbjct: 58 IKDKKLVAQLFE-----------------NNSFDLCYHLAASINVQDSIDDARATFENDT 100 Query: 130 -SMLCLTSSVLKAFPDSPGLNRTVV-----NISSLCALQPFKGWALYCAGKAARDMLFQV 183 L L ++ +V NI + L P K + Y K A + + Sbjct: 101 IGTFNLLEQCLNYDVKMVFMSTCMVYDKATNIQGISELDPIKPASPYAGSKIAAENMVLS 160 Query: 184 LALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQELKAKGKLVDCK 235 + V+ P Q+ E V + D K Sbjct: 161 YYY-AYKLPVVVIRPFNTYGPFQKTGGEGGVVAIFINNKLDNVPLNIYGDGK 211 >4J6F-A nrPDB Length = 382 Score = 35.4 bits (80), Expect = 0.022, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 26/76 (34%), Gaps = 11/76 (14%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDE----ALRQLE-------AEL 54 L+TGAS G G + L + + + + + + AE Sbjct: 206 AGETVLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDIGAQAVVTRGQGDLAEA 265 Query: 55 GAERSGLRVVRVPADL 70 SG R + V ADL Sbjct: 266 VEAASGGRPIDVVADL 281 >1UDA-A nrPDB Length = 338 Score = 35.4 bits (80), Expect = 0.024, Method: Composition-based stats. Identities = 28/177 (15%), Positives = 47/177 (26%), Gaps = 38/177 (21%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 L+TG S G L +L + ++ + LG + V D Sbjct: 3 VLVTGGSGYIGSHTCVQLLQNGHDVIILDNLCNSKRSVLPVIERLGGKHP----TFVEGD 58 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + EA + ++L +I+ AG L Y+ N+ Sbjct: 59 IRNEALMTEIL---------HDHAIDTVIHFAGLKAVGESVQKPL-------EYYDNNVN 102 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKG------------WALYCAGK 174 L L S++ A + SS + Y K Sbjct: 103 GTLRLISAMRAANVK------NFIFSSSATVYGDNPKIPYVESFPTGTPQSPYGKSK 153 >5YWN-A nrPDB Length = 334 Score = 35.0 bits (79), Expect = 0.030, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 86/278 (30%), Gaps = 63/278 (22%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPAD 69 ++GA+ G ++A +LS G +V S R++E L+ L + VV+V Sbjct: 5 VFVSGAT---GYLAQQIIALVLSKGYKVVGSVRSEEKGANLKK-LYGDDFSYEVVKVL-- 58 Query: 70 LGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLT 129 + GA E + + L S ++ D+ + A+N Sbjct: 59 --------EQKGAFDEALKKHPEVTIFL-------HTASPVTFEVEDTEKEILIPAIN-- 101 Query: 130 SMLCLTSSVLKAFPDSPGLNRTVVNISSLCAL-----QPFKGWAL---------YCAGK- 174 T VL++ D VV SS+ A+ L Y K Sbjct: 102 ----GTKYVLQSIKDVAPQITRVVYTSSVVAMSVPEELGSPDVVLSEASWSSLSYEQSKT 157 Query: 175 AARDML--FQVLA---------LEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRKGLQ 223 + A E+PN + P + + + + Sbjct: 158 HGVLAYFGSKQFAERAAWEFVEQEKPNFALSTVNPVYIFGPQAKDEEVKGTLNHSAEMVN 217 Query: 224 ELKAKGK----------LVDCKVSAQKLLSLLEKDEFK 251 + K +D + A+ L+ EKDE K Sbjct: 218 SVLKLNKDDDVPATTGTFIDVRDVAKAHLAAFEKDEAK 255 >2GN9-A nrPDB Length = 344 Score = 34.6 bits (78), Expect = 0.038, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 32/170 (18%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVV 64 L L+TG + FG+ + + +++ +R++ L+Q +E+ E + R+ Sbjct: 19 LDNQTILITGGTGSFGKCFVRKVLDTTN-AKKIIVYSRDE--LKQ--SEMAMEFNDPRMR 73 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYW 124 D+ L++L AL + + I+ A + L Sbjct: 74 FFIGDVRD---LERLNYALEGVD--------ICIHAAALKHVPIAEYNPL-------ECI 115 Query: 125 ALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWALYCAGK 174 N+ + ++ LK V+ +S+ A P LY A K Sbjct: 116 KTNIMGASNVINACLKNAISQ------VIALSTDKAANP---INLYGATK 156 >1I3M-A nrPDB Length = 348 Score = 34.6 bits (78), Expect = 0.046, Method: Composition-based stats. Identities = 33/195 (16%), Positives = 56/195 (28%), Gaps = 39/195 (20%) Query: 5 LGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELG--AERSGLR 62 + V L+TG + G L V+ L L E +G Sbjct: 1 MAEKV-LVTGGAGYIGSHTVLELLEAGYLPVVIDNFHNAFRGGGSLPESLRRVQELTGRS 59 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNN 122 V D+ + LQ+L K + +I+ AG L + Sbjct: 60 VEFEEMDILDQGALQRLF---------KKYSFMAVIHFAGLKAMGESVQKPL-------D 103 Query: 123 YWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQPFKGWA-------------L 169 Y+ +NLT + L + G+ +V SS + + Sbjct: 104 YYRVNLTGTIQLL-----EIMKAHGVK-NLVFSSS-ATVYGNPQYLPLDEAHPTGGCTNP 156 Query: 170 YCAGKAARDMLFQVL 184 Y K + + + L Sbjct: 157 YGKSKFFIEEMIRDL 171 >3SC6-A nrPDB Length = 287 Score = 34.3 bits (77), Expect = 0.063, Method: Composition-based stats. Identities = 23/161 (14%), Positives = 51/161 (31%), Gaps = 35/161 (21%) Query: 36 VLVLSARNDEALRQLEAELGAERSGLRVVRVPA-DLGAEAGLQQLLGALRELPRPKGLQR 94 ++++ N + +QL+ EL E + D+ + +QQ++ +R Sbjct: 7 RVIITGANGQLGKQLQEELNPEEYDIYPFDKKLLDITNISQVQQVVQEIRPH-------- 58 Query: 95 LLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVN 154 ++I+ A + + + +N + + S + +V Sbjct: 59 -IIIHCAAYTKVDQA-------EKERDLAYVINAIGARNVAVA-------SQLVGAKLVY 103 Query: 155 ISSLCALQP----------FKGWAL-YCAGKAARDMLFQVL 184 IS+ Q Y A K A + + L Sbjct: 104 ISTDYVFQGDRPEGYDEFHNPAPINIYGASKYAGEQFVKEL 144 >1IE3-A nrPDB Length = 312 Score = 33.9 bits (76), Expect = 0.066, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 43/109 (39%), Gaps = 4/109 (3%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 V +L GA+ G G+ LA LL + L GS L L + +L + +++ Sbjct: 2 KVAVL-GAAGGIGQALALLLKTQLPSGSELSLYDI-APVTPGVAVDLSHIPTAVKIKGFS 59 Query: 68 A-DLGAEAGLQQLLGALRELPRPKGLQRLLLIN-NAGSLGDVSKGFVDL 114 D ++ + R G+ R L N NAG + ++ + Sbjct: 60 GEDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKT 108 >4E0B-A nrPDB Length = 313 Score = 33.9 bits (76), Expect = 0.068, Method: Composition-based stats. Identities = 25/107 (23%), Positives = 43/107 (40%), Gaps = 4/107 (3%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 V ++ GA+ G G+ LA LL + L GS L L + A+L + + + Sbjct: 5 KVAVI-GAAGGIGQALALLLKNRLPAGSDLALYDI-APVTPGVAADLSHIPTHVSIKGYA 62 Query: 68 A-DLGAEAGLQQLLGALRELPRPKGLQRLLLIN-NAGSLGDVSKGFV 112 D ++ + R G+ R L N NAG + +++ Sbjct: 63 GEDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIA 109 >2PZM-A nrPDB Length = 330 Score = 33.5 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 62/208 (29%), Gaps = 48/208 (23%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG + G L V+ A + E+ +GL V + + Sbjct: 24 LITGGAGCLGSNLIEHWLPQGHEILVIDNFATG-------KREVLPPVAGLSV--IEGSV 74 Query: 71 GAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTS 130 L++ + + ++++A + D A N+ Sbjct: 75 TDAGLLERAFDSFKPTH---------VVHSAAAYKDP----------DDWAEDAATNVQG 115 Query: 131 MLCLTSSVLKAFPDSP---------GLNRTV-VNISSLCALQPFKGWALYCAGKAARDML 180 + + + KA G TV + I S P + Y K A + Sbjct: 116 SINVAKAASKAGVKRLLNFQTALCYGRPATVPIPIDS-----PTAPFTSYGISKTAGEAF 170 Query: 181 FQ-----VLALEEPNVRVLNYAPGPLDT 203 V++L NV A GP+ T Sbjct: 171 LMMSDVPVVSLRLANVTGPRLAIGPIPT 198 >2Q4B-A nrPDB Length = 253 Score = 32.7 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 14/79 (17%), Positives = 23/79 (29%), Gaps = 10/79 (12%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPA 68 L+TGAS G+ + S V R+ + G E+ G Sbjct: 6 TVLVTGASGRTGQ-IVYKKLKEGSDKFVAKGLVRSAQ---------GKEKIGGEADVFIG 55 Query: 69 DLGAEAGLQQLLGALRELP 87 D+ + + L Sbjct: 56 DITDADSINPAFQGIDALV 74 >2Q1W-A nrPDB Length = 333 Score = 32.3 bits (72), Expect = 0.19, Method: Composition-based stats. Identities = 31/181 (17%), Positives = 51/181 (28%), Gaps = 45/181 (24%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 +TG G +A LL L G +V R E + L V Sbjct: 22 KKVFITGICGQIGSHIAELL---LERGDKVVGIDNFATGRR----EHLKDHPNLT--FVE 72 Query: 68 ADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALN 127 + A + QL+ LQ +++ A S D N+ N Sbjct: 73 GSIADHALVNQLI---------GDLQPDAVVHTAASYKD---------PDDWYNDTL-TN 113 Query: 128 LTSMLCLTSSVLKAFPDSPGLNRTVVNISSLC-ALQP-----------FKGWALYCAGKA 175 + + + R V ++LC ++P + Y K+ Sbjct: 114 CVGGSNVVQAA-----KKNNVGRFVYFQTALCYGVKPIQQPVRLDHPRNPANSSYAISKS 168 Query: 176 A 176 A Sbjct: 169 A 169 >3ENK-A nrPDB Length = 341 Score = 32.3 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 4/76 (5%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 + L+TG + G A L L+ G +V++ + R+ A + +G Sbjct: 5 KGTILVTGGAGYIGSHTAVEL---LAHGYDVVIADNLVNSKREAIARIEK-ITGKTPAFH 60 Query: 67 PADLGAEAGLQQLLGA 82 D+ E L ++ A Sbjct: 61 ETDVSDERALARIFDA 76 >4UUP-A nrPDB Length = 341 Score = 32.3 bits (72), Expect = 0.24, Method: Composition-based stats. Identities = 30/116 (25%), Positives = 42/116 (36%), Gaps = 7/116 (6%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSV-LVLSARN----DEALRQLEAELGAERSGLRVV 64 L+TGA+ G LA +A G +VL +AL + EL Sbjct: 7 VLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTLAG 66 Query: 65 RVPADLGAEAGLQQLLG-ALRELPRPKGLQR-LLLINNAGSLGDVSKGFVDLSDST 118 V D EA + + PR G++R LL NAG K + + T Sbjct: 67 VVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPT 122 >1BXK-A nrPDB Length = 355 Score = 31.9 bits (71), Expect = 0.25, Method: Composition-based stats. Identities = 32/194 (16%), Positives = 53/194 (27%), Gaps = 46/194 (23%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADL 70 L+TG + G L + + S V+V L L +ER V D+ Sbjct: 5 LITGGAGFIGSALVRYIINETSDAVVVVDKLTYAGNLMSLAPVAQSERFAFEKV----DI 60 Query: 71 GAEAGLQQLLGA-----LRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWA 125 A L ++ + L + R + D F Sbjct: 61 CDRAELARVFTEHQPDCVMHLAAESHVDRSI---------DGPAAF------------IE 99 Query: 126 LNLTSMLCLTSSVL---KAFPDSPGLNRTVVNISSL-------------CALQPFKGWAL 169 N+ L + A + +IS+ P+ + Sbjct: 100 TNIVGTYTLLEAARAYWNALTEDKKSAFRFHHISTDEVYGDLHSTDDFFTETTPYAPSSP 159 Query: 170 YCAGKAARDMLFQV 183 Y A KA+ D L + Sbjct: 160 YSASKASSDHLVRA 173 >3VPX-A nrPDB Length = 364 Score = 31.9 bits (71), Expect = 0.26, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 2 EGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGL 61 + L + +G G L L G+ L+++ N+EA+++ GA G+ Sbjct: 168 DDSLAGKTVAV----QGVGNVAYALCEYLHEEGAKLIITDINEEAVQRAVDAFGATAVGI 223 Query: 62 RVVRVP-ADLGAEAGLQQLLG 81 + AD+ A L ++ Sbjct: 224 NEIYSQEADIFAPCALGAIIN 244 >2V6G-A nrPDB Length = 364 Score = 31.6 bits (70), Expect = 0.37, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 24/83 (28%), Gaps = 11/83 (13%) Query: 9 VCLLTGASRGFGRTLAPL--LASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 V L+ G + G +LA + LA + AR + V Sbjct: 3 VALIVGVTGIIGNSLAEILPLADTPGGPWKVYGVARRTRPA---------WHEDNPINYV 53 Query: 67 PADLGAEAGLQQLLGALRELPRP 89 D+ Q L L ++ Sbjct: 54 QCDISDPDDSQAKLSPLTDVTHV 76 >1O89-A nrPDB Length = 345 Score = 31.6 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 18/43 (41%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAE 53 ++TGAS G G T LL L + E L+ L A Sbjct: 172 VVTGASGGVGSTAVALLHKLGYQVVAVSGRESTHEYLKSLGAS 214 >6ACF-A nrPDB Length = 367 Score = 30.8 bits (68), Expect = 0.56, Method: Composition-based stats. Identities = 16/68 (23%), Positives = 27/68 (39%), Gaps = 5/68 (7%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L V + +G G L L G+ L+++ N EA+ + E GA+ Sbjct: 170 SLEGKVVAV----QGVGNVAYHLCRHLHEEGAKLIVTDINKEAVARAVEEFGAKAVDPND 225 Query: 64 V-RVPADL 70 + V D+ Sbjct: 226 IYGVECDI 233 >5N2I-A nrPDB Length = 232 Score = 30.8 bits (68), Expect = 0.67, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 3/45 (6%) Query: 12 LTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGA 56 + G + GR LA A G ++L +R+ E + + AELG Sbjct: 24 VLGGTGDQGRGLARRFAM---AGHEVILGSRSAERAQAVAAELGE 65 >4GFJ-A nrPDB Length = 685 Score = 30.0 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 34/93 (36%), Gaps = 8/93 (8%) Query: 4 GLGRAV--CLLTG-AS----RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGA 56 G+G V L+ G AS RG R A L S + + + L Sbjct: 454 GVGERVLRSLVPGYASLISIRGIDRERAERLLKKYGGYSKVREAGVEELREDGLTDAQIR 513 Query: 57 ERSGLRVV-RVPADLGAEAGLQQLLGALRELPR 88 E GL+ + + DL L++ G+ + R Sbjct: 514 ELKGLKTLESIVGDLEKADELKRKYGSASAVRR 546 >4A10-A nrPDB Length = 447 Score = 29.6 bits (65), Expect = 1.2, Method: Composition-based stats. Identities = 24/103 (23%), Positives = 43/103 (41%), Gaps = 14/103 (13%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSP-GSVLVLSARNDEALRQLEAELGAERSGLRVV 64 + L+ GAS G G + A +V SA+ + A+R L +L R+ L + Sbjct: 220 QGDIVLIWGASGGLG-SYAIQFVKNGGGIPVAVVSSAQKEAAVRALGCDLVINRAELGIT 278 Query: 65 RVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDV 107 AD ++++ R+L + L++ AG D+ Sbjct: 279 DDIAD-----DPRRVVETGRKLAK-------LVVEKAGREPDI 309 >1HYE-A nrPDB Length = 313 Score = 29.6 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 50/122 (40%), Gaps = 13/122 (10%) Query: 8 AVCLLTGASRGFGRTLAPLLASLL-SPGSVLVLSARNDEALRQLEAELGAERSGLRV--- 63 V ++ GAS G A LLA VL+ + L L ++ +G R Sbjct: 2 KVTII-GASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60 Query: 64 VRVPAD----LGAEAGLQQLLGALRELPRPKGLQRLLLI-NNAGSLGDVSKGFVDLSDST 118 + V +D + E+ + + +PR +G+ R+ L NA +G +K ++ D+ Sbjct: 61 IYVESDENLRIIDESDV---VIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEICDTK 117 Query: 119 QV 120 Sbjct: 118 IF 119 >5A0V-A nrPDB Length = 561 Score = 29.6 bits (65), Expect = 1.3, Method: Composition-based stats. Identities = 29/175 (16%), Positives = 55/175 (31%), Gaps = 23/175 (13%) Query: 26 LLASLLSPGSVLVLSARNDEAL-------RQLEAELGAERSGLRVVRVPADLGAE-AGLQ 77 A L G L+L+ + + R + L + R + A + +Q Sbjct: 190 AFARLSEEGIDLLLADSTNAEVPGFVPPERDISNVLRQVFANARKRIIVASFASHVHRIQ 249 Query: 78 QLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLCLT-- 135 Q+L A E R ++ N G D+ V V L + ++ + Sbjct: 250 QILDAAHEYGRRVAFVGRSMVRNMGIARDLGYLKVPPGLVVDVKTLDDLPDSEVVLVCTG 309 Query: 136 -----SSVLKAFPDSPGLNRTVVNISSL---CALQPFKGWALYCAGKAARDMLFQ 182 + L + +VN ++ +L P A+Y + L + Sbjct: 310 SQGEPMAALSRM-ANRDHQIRIVNGDTVILASSLIPGNENAVYRV----INGLTR 359 >5HM5-A nrPDB Length = 854 Score = 29.6 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 34/93 (36%), Gaps = 8/93 (8%) Query: 4 GLGRAV--CLLTG-AS----RGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGA 56 G+G V L+ G AS RG R A L S + + + L Sbjct: 454 GVGERVLRSLVPGYASLISIRGIDRERAERLLKKYGGYSKVREAGVEELREDGLTDAQIR 513 Query: 57 ERSGLRVV-RVPADLGAEAGLQQLLGALRELPR 88 E GL+ + + DL L++ G+ + R Sbjct: 514 ELKGLKTLESIVGDLEKADELKRKYGSASAVRR 546 >1R66-A nrPDB Length = 337 Score = 29.2 bits (64), Expect = 1.8, Method: Composition-based stats. Identities = 33/190 (17%), Positives = 58/190 (30%), Gaps = 46/190 (24%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGS----VLVLSARNDEALRQLEAELGAERSGLRVVRV 66 L+TG + G L + P V+VL + R A L + R+ V Sbjct: 4 LVTGGAGFIGSHFVRQLLAGAYPDVPADEVIVLDSLTYAGNR---ANLAPVDADPRLRFV 60 Query: 67 PADLGAE---AGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 D+ A + + A+ + R + AG+ + Sbjct: 61 HGDIRDAGLLARELRGVDAIVHFAAESHVDRSI----AGAS-----------------VF 99 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTV----------VNISSLCALQPFKGWALYCAG 173 N+ L + A G+ R V ++ S P + + Y A Sbjct: 100 TETNVQGTQTLLQCAVDA-----GVGRVVHVSTDEVYGSIDSGSWTESSPLEPNSPYAAS 154 Query: 174 KAARDMLFQV 183 KA D++ + Sbjct: 155 KAGSDLVARA 164 >3F6S-A nrPDB Length = 148 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 18/92 (19%), Positives = 30/92 (32%), Gaps = 9/92 (9%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVP 67 V ++ G+S G ++A L L++ G V +A + A+ G V Sbjct: 3 KVLIVFGSSTGNTESIAQKLEELIAAGGHEVTLLNAADASAENLAD------GYDAVLFG 56 Query: 68 ADLGAEAGLQ---QLLGALRELPRPKGLQRLL 96 L+ L E R R + Sbjct: 57 CSAWGMEDLEMQDDFLSLFEEFDRIGLAGRKV 88 >5NUE-A nrPDB Length = 332 Score = 28.9 bits (63), Expect = 2.2, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 40/92 (43%), Gaps = 7/92 (7%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSV--LVLSARN----DEALRQLEAEL-GAERSGLR 62 L+TGA+ G L P++A + G+ ++L + EAL ++ EL A L+ Sbjct: 8 VLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPLLK 67 Query: 63 VVRVPADLGAEAGLQQLLGALRELPRPKGLQR 94 V D + + PR +G++R Sbjct: 68 GVVATTDAVEGCTGVNVAVMVGGFPRKEGMER 99 >5GXF-A nrPDB Length = 330 Score = 28.9 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 18/44 (40%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAE 53 L+TGA+ G G +LA L + + + L L A Sbjct: 153 VLVTGAAGGVGSVATAILAHLGYEVAAVTGRPETADYLTSLGAT 196 >5UZH-A nrPDB Length = 345 Score = 28.9 bits (63), Expect = 2.6, Method: Composition-based stats. Identities = 15/83 (18%), Positives = 32/83 (38%), Gaps = 10/83 (12%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEA-----LRQLEAELGAERSGLR 62 V L+TG + G LA L L G ++ R + + L ++ ++ + Sbjct: 2 KVALITGITGQDGSYLAEFL---LEKGYMVYGIIRRSSSFNTGRVEHLYKDIHITKAKFK 58 Query: 63 VVRVPADLGAEAGLQQLLGALRE 85 ++ DL L ++ ++ Sbjct: 59 LLY--GDLTDTGNLISIIAKIKP 79 >5A3V-A nrPDB Length = 329 Score = 28.5 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 18/53 (33%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 1 MEGGLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAE 53 ++G +A L+T AS G G A LA L + ARN E ++ L A+ Sbjct: 150 LDGTGKKANILVTAASGGVGH-YAVQLAKLANAHVTATCGARNIEFVKSLGAD 201 >4K28-A nrPDB Length = 269 Score = 28.5 bits (62), Expect = 3.3, Method: Composition-based stats. Identities = 13/58 (22%), Positives = 21/58 (36%), Gaps = 3/58 (5%) Query: 6 GRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRV 63 L+ G G G +A LA + + + L + + + LG GL V Sbjct: 124 AGKRALVIGCG-GVGSAIAYALAE--AGIASITLCDPSTARMGAVCELLGNGFPGLTV 178 >1VHV-A nrPDB Length = 268 Score = 28.1 bits (61), Expect = 3.6, Method: Composition-based stats. Identities = 25/128 (19%), Positives = 51/128 (39%), Gaps = 9/128 (7%) Query: 59 SGLRVVRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDST 118 GL VR ++ E +LL ++ E+ G + + L D+ + L + Sbjct: 31 KGLEAVREADEVYVEYYTSKLLSSIEEMEEFFGKRVVEL-----ERSDLEENSFRLIERA 85 Query: 119 QVNNYWALNLTS--MLCLTSSVLKAFPDSPGLNRTVVNISSLC-ALQPFKGWALYCAGKA 175 + + L + M+ T S +K + G+ +++ +S+ A+ G Y GK+ Sbjct: 86 KSKSVVLL-VPGDPMVATTHSAIKLEAERKGVKTRIIHGASISTAVCGLTGLHNYRFGKS 144 Query: 176 ARDMLFQV 183 A + Sbjct: 145 ATVSWHRS 152 >4EZI-A nrPDB Length = 377 Score = 28.1 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 19/32 (59%) Query: 168 ALYCAGKAARDMLFQVLALEEPNVRVLNYAPG 199 A Y G + ++F++LA E P++ V APG Sbjct: 166 AGYSEGGFSTIVMFEMLAKEYPDLPVSAVAPG 197 >4UUO-A nrPDB Length = 340 Score = 28.1 bits (61), Expect = 3.7, Method: Composition-based stats. Identities = 29/142 (20%), Positives = 42/142 (29%), Gaps = 7/142 (4%) Query: 11 LLTGASRGFGRTLAPLLASLLSPGSV-LVLSARN----DEALRQLEAELGAERSGLRVVR 65 L+TGA+ G L +A G +VL +AL EL Sbjct: 7 LITGAAGQIGYALTFRIAKGDLCGDRKVVLHLLEIPFGMKALEGCVMELQDCAFPNVAGI 66 Query: 66 VPADLGAEAGLQQLLG-ALRELPRPKGLQR-LLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 V D EA + + PR G+ R LL N G K D + T Sbjct: 67 VWTDKVEEAFKGVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALNDYAKPTVKVLV 126 Query: 124 WALNLTSMLCLTSSVLKAFPDS 145 + + + + Sbjct: 127 VGNPANTNCLIAQASAPKLQNK 148 >6EUG-A nrPDB Length = 374 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 19/51 (37%), Gaps = 1/51 (1%) Query: 170 YCAGKAARDMLFQVLALEEPNVRVLNYAPGPLDTDMQQLARETSVDPDMRK 220 Y +AA + A +R PG +M + R+ +P+ K Sbjct: 136 YGPARAAV-AVSDSPAGPYRFIRSGRVNPGAYPLNMTRKERKMKWNPEEYK 185 >4Y1B-A nrPDB Length = 425 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 19/80 (23%), Positives = 31/80 (38%), Gaps = 2/80 (2%) Query: 10 CLLTGASRGFGRTLAPLLASLLSPGSVLVLSARND-EALRQLEAELGAERSGLRVVRVPA 68 L+ G + G G ++A L + V V+S+ E +L A+ +R Sbjct: 225 VLIWGGAGGLG-SIAIQLVRHVGGIPVAVVSSEERGEFCMRLGAKGWIDRREFDHWGRLP 283 Query: 69 DLGAEAGLQQLLGALRELPR 88 D E ++Q L R R Sbjct: 284 DTTDEEAMKQWLDGARAFGR 303 >4MIE-A nrPDB Length = 351 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 12/58 (20%), Positives = 23/58 (39%), Gaps = 4/58 (6%) Query: 3 GGLGRAVCLL-TGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERS 59 G + V ++ TGA GR L ++L+ V+ ++ + EA + Sbjct: 11 GSMVVKVGVIGTGA---MGRAHIDRLTNVLTGAEVVAVTDIDHEAAEAAVRDFHLNAK 65 >3AFP-A nrPDB Length = 168 Score = 28.1 bits (61), Expect = 4.5, Method: Composition-based stats. Identities = 10/62 (16%), Positives = 23/62 (37%), Gaps = 7/62 (11%) Query: 19 FGRTLAPLLASLLSPGSVLVLSAR-------NDEALRQLEAELGAERSGLRVVRVPADLG 71 R A +A L+ G+ ++++ R E ++ E+ + G + A + Sbjct: 59 IWREAAENVAESLTRGARVIVTGRLKQRSFETREGEKRTVVEVEVDEIGPSLRYATAKVN 118 Query: 72 AE 73 Sbjct: 119 KA 120 >3RUE-A nrPDB Length = 351 Score = 27.7 bits (60), Expect = 4.6, Method: Composition-based stats. Identities = 29/181 (16%), Positives = 54/181 (29%), Gaps = 41/181 (22%) Query: 8 AVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEA----LRQLEAELGAERSGLRV 63 L+TG + G + LL LL V++ L +++ + E+ R Sbjct: 26 KTWLITGVAGFIG---SNLLEKLLKLNQVVIGLDNFSTGHQYNLDEVKTLVSTEQWS-RF 81 Query: 64 VRVPADLGAEAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNY 123 + D+ +Q++ + + +LG V + VD + Sbjct: 82 CFIEGDIRDLTTCEQVMKGVDHVLHQ------------AALGSVPRSIVDPITTN----- 124 Query: 124 WALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCA----------LQPFKGWALYCAG 173 A N+T L + + A S + SS + Y Sbjct: 125 -ATNITGFLNILHAAKNAQVQSFTYAAS----SSTYGDHPALPKVEENIGNP-LSPYAVT 178 Query: 174 K 174 K Sbjct: 179 K 179 >3UQZ-A nrPDB Length = 288 Score = 27.7 bits (60), Expect = 4.9, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 28/60 (46%), Gaps = 7/60 (11%) Query: 4 GLGRAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDE-----ALRQLEAELGAER 58 GL + +++G ++G A +A+L + G + + + A ++L+ +G + Sbjct: 131 GLENELVIVSGLAKGI--DTAAHMAALQNGGKTIAVIGTGLDVFYPKANKRLQDYIGNDH 188 >1WDK-C nrPDB Length = 390 Score = 27.7 bits (60), Expect = 4.9, Method: Composition-based stats. Identities = 6/27 (22%), Positives = 11/27 (40%) Query: 155 ISSLCALQPFKGWALYCAGKAARDMLF 181 +S + + P +LY A + L Sbjct: 127 VSMMHGVDPNPHMSLYAAKASGMMGLT 153 >2P31-A nrPDB Length = 181 Score = 27.7 bits (60), Expect = 5.3, Method: Composition-based stats. Identities = 10/52 (19%), Positives = 18/52 (34%), Gaps = 7/52 (13%) Query: 111 FVDLSDSTQVNNYWALNLTSMLCLTSSVLKAFPDSPGLNRTVVNISSLCALQ 162 F + ++ A+N+ L + G VVN++S C Sbjct: 20 FQSMQQEQDFYDFKAVNIRGKLV-------SLEKYRGSVSLVVNVASECGFT 64 >1RK6-A nrPDB Length = 496 Score = 27.7 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 12/55 (21%), Positives = 22/55 (40%), Gaps = 3/55 (5%) Query: 175 AARDMLFQVLALEEPNVRVLNYAPGPLDT---DMQQLARETSVDPDMRKGLQELK 226 AA L A +V +PG +D+ D L + + P + +G+ + Sbjct: 51 AAVGDLSASSARRRIDVAGKVVSPGFIDSHTHDDNYLLKHRDMTPKISQGVTTVV 105 >5J9G-A nrPDB Length = 338 Score = 27.7 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 43/130 (33%), Gaps = 12/130 (9%) Query: 13 TGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRVPADLGA 72 TGA++ G + L L + + + + +L + LG V AD Sbjct: 216 TGAAKAIGLVIPELNGKLNGHAQRVPVPDGS---VTELVSILGKN--------VTADEVN 264 Query: 73 EAGLQQLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSML 132 EA +++ E + +L AGS+ D ++ V + Q+ A Sbjct: 265 EA-MKKYESPSFEYEPNNVVSSDILGRTAGSIFDPTQTMVTTAGDKQLVKTVAWYDNEYS 323 Query: 133 CLTSSVLKAF 142 V Sbjct: 324 FTCQMVRTLL 333 >2P8Y-T nrPDB Length = 842 Score = 27.3 bits (59), Expect = 7.4, Method: Composition-based stats. Identities = 10/83 (12%), Positives = 27/83 (32%), Gaps = 5/83 (6%) Query: 78 QLLGALRELPRPKGLQRLLLINNAGSLGDVSKGFVDLSDSTQVNNYWALNLTSMLC---- 133 + + + + K L+ AG + G +D+ + + + S Sbjct: 20 RNMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKSTAISLYS 79 Query: 134 -LTSSVLKAFPDSPGLNRTVVNI 155 ++ +K N ++N+ Sbjct: 80 EMSDEDVKEIKQKTDGNSFLINL 102 >5F5N-A nrPDB Length = 289 Score = 26.9 bits (58), Expect = 8.1, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 27/86 (31%), Gaps = 9/86 (10%) Query: 7 RAVCLLTGASRGFGRTLAPLLASLLSPGSVLVLSARNDEALRQLEAELGAERSGLRVVRV 66 L+TGA+ G L + P LV R + + V V Sbjct: 1 NRTILVTGATGTQGGATVRALLARGRPVRALV---------RDPGTDAARALAAAGVSLV 51 Query: 67 PADLGAEAGLQQLLGALRELPRPKGL 92 DL +A L+ + + + + Sbjct: 52 TGDLNDQASLRAAMADVHGVFSVQTF 77 >2Y53-A nrPDB Length = 534 Score = 26.9 bits (58), Expect = 8.6, Method: Composition-based stats. Identities = 11/58 (18%), Positives = 19/58 (32%), Gaps = 1/58 (1%) Query: 9 VCLLTGASRGFGRTLAPLLASLLSPGS-VLVLSARNDEALRQLEAELGAERSGLRVVR 65 V L+ +S G A A + + A+ L + L A+R + Sbjct: 33 VALVRVSSEGLDLARAFSFAREDGGAALRALTYAQRAARLADIVKLLQAKRGDYYAIA 90 >1UE7-A nrPDB Length = 164 Score = 26.9 bits (58), Expect = 9.8, Method: Composition-based stats. Identities = 11/62 (17%), Positives = 23/62 (37%), Gaps = 7/62 (11%) Query: 19 FGRTLAPLLASLLSPGSVLVLSAR-------NDEALRQLEAELGAERSGLRVVRVPADLG 71 R A +A L+ G+ +++S R E ++ E+ + G + A + Sbjct: 59 IWREAAENVAESLTRGARVIVSGRLKQRSFETREGEKRTVIEVEVDEIGPSLRYATAKVN 118 Query: 72 AE 73 Sbjct: 119 KA 120 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.135 0.358 Lambda K H 0.267 0.0417 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,083,478 Number of Sequences: 36641 Number of extensions: 335467 Number of successful extensions: 2171 Number of sequences better than 10.0: 262 Number of HSP's better than 10.0 without gapping: 209 Number of HSP's successfully gapped in prelim test: 161 Number of HSP's that attempted gapping in prelim test: 1342 Number of HSP's gapped (non-prelim): 387 length of query: 261 length of database: 10,336,785 effective HSP length: 95 effective length of query: 166 effective length of database: 6,855,890 effective search space: 1138077740 effective search space used: 1138077740 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (26.9 bits)