BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P34897 (504 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5X3V-A nrPDB 999 0.0 1RVY-A nrPDB 615 e-176 1BJ4-A nrPDB 615 e-176 1EJI-A nrPDB 614 e-176 6CCZ-A nrPDB 564 e-161 5Z0Y-A nrPDB 557 e-159 4O6Z-A nrPDB 413 e-115 5XMU-A nrPDB 410 e-115 2DKJ-A nrPDB 368 e-102 1YJS-A nrPDB 363 e-100 5VMB-A nrPDB 359 2e-99 3H7F-A nrPDB 357 8e-99 3GBX-A nrPDB 353 1e-97 3N0L-A nrPDB 352 2e-97 4J5U-A nrPDB 351 5e-97 3G8M-A nrPDB 349 1e-96 3PGY-A nrPDB 349 2e-96 4P3M-A nrPDB 348 3e-96 4WXB-A nrPDB 345 3e-95 3ECD-A nrPDB 339 2e-93 4OTL-A nrPDB 332 3e-91 5VC2-A nrPDB 323 1e-88 4BHD-A nrPDB 186 1e-47 5XNI-A nrPDB 30 1.7 3TC3-A nrPDB 30 3.1 2DC1-A nrPDB 29 5.0 2DPD-A nrPDB 28 9.9 >5X3V-A nrPDB Length = 496 Score = 999 bits (2583), Expect = 0.0, Method: Compositional matrix adjust. Identities = 482/483 (99%), Positives = 483/483 (100%) Query: 22 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS 81 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS Sbjct: 1 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS 60 Query: 82 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY 141 RAALEALGSCLNN+YSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY Sbjct: 61 RAALEALGSCLNNRYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY 120 Query: 142 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 201 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT Sbjct: 121 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 180 Query: 202 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA Sbjct: 181 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA 240 Query: 262 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP 321 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP Sbjct: 241 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP 300 Query: 322 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL 381 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL Sbjct: 301 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL 360 Query: 382 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF 441 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF Sbjct: 361 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF 420 Query: 442 RRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 RRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF Sbjct: 421 RRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 480 Query: 502 DEH 504 DEH Sbjct: 481 DEH 483 >1RVY-A nrPDB Length = 483 Score = 615 bits (1586), Expect = e-176, Method: Compositional matrix adjust. Identities = 300/467 (64%), Positives = 367/467 (78%), Gaps = 8/467 (1%) Query: 43 WTGQES-----LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYS 97 W+ E L DSD E+++++++E +RQ GLELIASENF SRA LEALGSCLNNKYS Sbjct: 14 WSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 73 Query: 98 EGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQP 157 +GYPG+RYYGG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++P Sbjct: 74 QGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEP 133 Query: 158 HDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFR 217 H RIMGLDLPDGGHLTHG+M+D K+ISATSIFFESM YK+NP TG IDY++L ARLF Sbjct: 134 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFH 193 Query: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 P+LIIAGTS Y+R +DY R+R++ DE A+L+ADMAHISGLV A V+PSPF+H +VTTT Sbjct: 194 PKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTT 253 Query: 278 THKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAV 337 THKTLRG R+G+IFYR+GV++VDPKTG+EI Y E IN AVFP LQGGPHNHAIA VAV Sbjct: 254 THKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 313 Query: 338 ALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAE 397 ALKQA TP F+EY QV+ N RA++ AL+E GY +V+GG+DNHL+LVDLR KG DG RAE Sbjct: 314 ALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 373 Query: 398 RVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 +VLE SI NKNTCPGD+SA+ P GLRLG PALTSR E DF++V FI G+ + ++ Sbjct: 374 KVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQ 433 Query: 458 VKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 ++ T A L++FK L D + + + LRQ VE FA FP+PG Sbjct: 434 IQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGL 480 >1BJ4-A nrPDB Length = 470 Score = 615 bits (1586), Expect = e-176, Method: Compositional matrix adjust. Identities = 303/458 (66%), Positives = 364/458 (79%), Gaps = 4/458 (0%) Query: 47 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYY 106 + L DSD E++ ++++E +RQ GLELIASENF SRA LEALGSCLNNKYSEGYPG+RYY Sbjct: 14 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 73 Query: 107 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 166 GG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++PH RIMGLDL Sbjct: 74 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 133 Query: 167 PDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTS 226 PDGGHLTHG+M+D K+ISATSIFFESMPYK+NP TG I+Y+QL ARLF P+LIIAGTS Sbjct: 134 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 193 Query: 227 AYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGAR 286 Y+R ++YAR+R++ DE A+L+ADMAHISGLVAA V+PSPF+H +VTTTTHKTLRG R Sbjct: 194 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 253 Query: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346 +G+IFYRKGVK+VDP TG+EI Y E IN AVFP LQGGPHNHAIA VAVALKQA T Sbjct: 254 AGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 313 Query: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406 F+ Y QV+ N RA+++AL E GY +V+GG+DNHL+LVDLR KG DG RAE+VLE SI Sbjct: 314 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 373 Query: 407 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT---A 463 NKNTCPGDRSA+ P GLRLG PALTSR E DF++V FI G+ + L+++S T A Sbjct: 374 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVAA 433 Query: 464 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 L++FK L D + A LR+ VE FA FP+PG Sbjct: 434 TLKEFKERLAGDKYQAAVQA-LREEVESFASLFPLPGL 470 >1EJI-A nrPDB Length = 478 Score = 614 bits (1584), Expect = e-176, Method: Compositional matrix adjust. Identities = 300/467 (64%), Positives = 365/467 (78%), Gaps = 8/467 (1%) Query: 43 WTGQES-----LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYS 97 W E L DSD E++ ++++E +RQ GLELIASENF SRA LEALGS LNNKYS Sbjct: 9 WASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSSLNNKYS 68 Query: 98 EGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQP 157 EGYPG+RYYGG E +DE+E+LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++P Sbjct: 69 EGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEP 128 Query: 158 HDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFR 217 H RIMGLDLPDGGHLTHG+M+D K+ISATSIFFESMPYK+ P+TG I+Y+QL A LF Sbjct: 129 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLEENASLFH 188 Query: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 P+LIIAGTS Y+R +DYAR+R++ D+ A+L+ADMAHISGLVAA V+PSPF+H +VTTT Sbjct: 189 PKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 248 Query: 278 THKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAV 337 THKTLRG R+G+IFYRKGV++VDPKTG+E Y E IN AVFP LQGGPHNHAIA VAV Sbjct: 249 THKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHAIAGVAV 308 Query: 338 ALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAE 397 ALKQA T F+ Y LQVL N RA++DAL E GY +V+GG+DNHL+L+DLR KG DG RAE Sbjct: 309 ALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAE 368 Query: 398 RVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 +VLE SI NKNTCPGD+SA+ P GLRLG PALTSR E+DF++V FI G+ + L+ Sbjct: 369 KVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQ 428 Query: 458 VKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 ++S A L++FK L D + +A LR+ VE FA F +PG Sbjct: 429 IQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGL 475 >6CCZ-A nrPDB Length = 455 Score = 564 bits (1453), Expect = e-161, Method: Compositional matrix adjust. Identities = 270/456 (59%), Positives = 344/456 (75%), Gaps = 14/456 (3%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 LS++DP++ ++ +EKDRQ R LELIASENF S+A +EA+GSCL NKYSEG PGKRYYGG Sbjct: 9 LSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGG 68 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E +DE+E+LCQ+RAL AF LD +WGVNVQP SGSPAN AVYTA+L+PHDRIMGLDLP Sbjct: 69 NEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPH 128 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHL+HG+M+ +R+S TSI+FESMPY+L+ TG+IDY+ L TA LFRP+LIIAG SAY Sbjct: 129 GGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAY 188 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R IDYAR R++ D V A L+ DMAH+SGL+AA V+ PF+ DIVTTTTHK+LRG R G Sbjct: 189 PRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGG 248 Query: 289 LIFYRK-GVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 +IF++K V VD E IN AVFP LQGGPHNH I +AV LK A +P F Sbjct: 249 MIFFKKDAVHGVD----------LESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDF 298 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y QV+ N RA+A+ L+E Y LVSGG+DNHLVLVDLRP G+DGAR E++L++ SIT Sbjct: 299 KNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITL 358 Query: 408 NKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTA--KL 465 NKN+ PGD+SA+ PGG+R+G+PA+T+R E +F + D I EGV I LE KS + K+ Sbjct: 359 NKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKV 418 Query: 466 QDFKSFLLK-DSETSQRLANLRQRVEQFARAFPMPG 500 QDF +F+L + +++NLR++VE A +P+PG Sbjct: 419 QDFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPG 454 >5Z0Y-A nrPDB Length = 470 Score = 557 bits (1435), Expect = e-159, Method: Compositional matrix adjust. Identities = 258/454 (56%), Positives = 350/454 (77%), Gaps = 7/454 (1%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L+++DPE+ ++++ E DRQ + LIASENF S + +ALG+ + NKYSEGYPG RYYGG Sbjct: 18 LAETDPEVNQIIKDEVDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGG 77 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E +D +E+LCQ+RAL+AF LD ++WGVNVQ SGSPANL VY A+++PHDR+MGLDLP Sbjct: 78 NEHIDRMEILCQQRALKAFHLDGSRWGVNVQTLSGSPANLQVYQAIMKPHDRLMGLDLPH 137 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHL+HGY +D ++ISA S +FE+MPY+++ +TG+IDY+ L TA L+RP++++AGTSAY Sbjct: 138 GGHLSHGYQTDTRKISAVSTYFETMPYRVDLETGIIDYDMLEKTAVLYRPKVLVAGTSAY 197 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 RLIDY RMRE+ D+V A+L+ DMAHISGL+AA VIPSPF++ADIVTTTTHK+LRG R Sbjct: 198 CRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGA 257 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +IF+RKGV++V+PKTG+EI Y E+ INF+VFP QGGPHNH IAA+A ALKQA TP F+ Sbjct: 258 MIFFRKGVRSVNPKTGKEIYYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFK 317 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 +Y QVLKNA+A+ + GY LVS GTD+H+VLV L+ K +DGAR E V E ++I N Sbjct: 318 QYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGARIETVCENINIALN 377 Query: 409 KNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKS----KTAK 464 KN+ PGDRSA+ PGG+R+GAPA+T+R E+DF ++ ++ID+ V +V+S + K Sbjct: 378 KNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYAKKVQSELPIEANK 437 Query: 465 LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 L+DFK+ K +E S + L+ + +A FP+ Sbjct: 438 LKDFKA---KIAEGSDEITQLKNEISAWAGEFPL 468 >4O6Z-A nrPDB Length = 480 Score = 413 bits (1061), Expect = e-115, Method: Compositional matrix adjust. Identities = 208/458 (45%), Positives = 294/458 (64%), Gaps = 17/458 (3%) Query: 42 GWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYP 101 G + L D E+++LL++EK+RQ + LIASEN + A E LG ++NKYSEGYP Sbjct: 38 GMFNNDPLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYP 97 Query: 102 GKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRI 161 KRYYGG + VD+IE LC +RALEAF++ +WGVNVQP SGS AN+ AL+ +I Sbjct: 98 HKRYYGGNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKI 157 Query: 162 MGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLI 221 MG+ L GGHLTHG+ + K++S TS FES YK N + G +D + A F+P++I Sbjct: 158 MGMHLCSGGHLTHGFFDEKKKVSITSDLFESKLYKCNSE-GYVDMESVRNLALSFQPKVI 216 Query: 222 IAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKT 281 I G ++Y R IDY RE+CDEV A+L AD++HIS VA ++ +PF +AD+VTTTTHK Sbjct: 217 ICGYTSYPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKI 276 Query: 282 LRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQ 341 LRG RS LIF+ K + P + +IN +VFPS QGGPHN+ IAAVA LK+ Sbjct: 277 LRGPRSALIFFNK----------KRNP-GIDQKINSSVFPSFQGGPHNNKIAAVACQLKE 325 Query: 342 ACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLE 401 TP F+EY+ QVL N++A+A+ LL+R LV+ GTDNHL++VDLR + G++ + Sbjct: 326 VNTPEFKEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCN 385 Query: 402 LVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSK 461 ++I NKNT P D ++P G+R+G PALT+R +E D + D + + + + E++ K Sbjct: 386 AINIALNKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQK 445 Query: 462 TA-KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 KL DFK L+ + ++ L++ V Q+A+ P Sbjct: 446 YGKKLVDFKKGLVNNP----KIDELKKEVVQWAKNLPF 479 >5XMU-A nrPDB Length = 442 Score = 410 bits (1055), Expect = e-115, Method: Compositional matrix adjust. Identities = 206/456 (45%), Positives = 293/456 (64%), Gaps = 17/456 (3%) Query: 45 GQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKR 104 E L D E+ ++L E+ RQ + LIASEN + A E LG+ ++NKYSEGYP KR Sbjct: 3 NNEPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSNKYSEGYPKKR 62 Query: 105 YYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGL 164 YYGG + +D+IE LCQ+RALEAF++ +WGVNVQP SGS AN+ AL+ +IMG+ Sbjct: 63 YYGGNDFIDKIEELCQKRALEAFNVSDEEWGVNVQPLSGSAANVQALYALVGVKGKIMGM 122 Query: 165 DLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAG 224 L GGHLTHG+ + K++S TS FES YK N + G +D + + A F+P++II G Sbjct: 123 HLCSGGHLTHGFFDEKKKVSITSDMFESKLYKCNSQ-GYVDLDAVREMALSFKPKVIICG 181 Query: 225 TSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRG 284 ++Y R IDY + R++CDEV A+L AD++HIS VA ++ +PF HAD+VTTTTHK LRG Sbjct: 182 YTSYPRDIDYQQFRQICDEVNAYLFADISHISSFVACNILNNPFLHADVVTTTTHKILRG 241 Query: 285 ARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACT 344 RS LIF+ K + P E +IN AVFPS QGGPHN+ IAAVA LK+ + Sbjct: 242 PRSALIFFNK----------KRNP-GIEQKINSAVFPSFQGGPHNNKIAAVACQLKEVHS 290 Query: 345 PMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVS 404 P F+EY+ QVL N++A+A AL+ + LV+ GTDNHL++VDLR + G++ + ++ Sbjct: 291 PAFKEYTQQVLLNSKALAKALISKQIDLVTNGTDNHLIVVDLRKFSITGSKLQETCNAIN 350 Query: 405 ITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTA- 463 ++ NKNT P D ++P G+R+G PA+T+R +E D + D + + I ++++ + Sbjct: 351 VSLNKNTIPSDVDCVSPSGVRIGTPAMTTRGAKEKDMEFIADVLARAIKITVDLQEQYGK 410 Query: 464 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMP 499 KL DFK L +++ Q L+Q V +A A P P Sbjct: 411 KLVDFKKGLPGNAQLQQ----LKQEVVTWAGALPFP 442 >2DKJ-A nrPDB Length = 407 Score = 368 bits (944), Expect = e-102, Method: Compositional matrix adjust. Identities = 205/448 (45%), Positives = 270/448 (60%), Gaps = 49/448 (10%) Query: 53 DPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVV 112 D ++EL+ E+ RQ GLELIASENF S+ EA+GS L NKY+EGYPG RYYGG EV+ Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEVI 67 Query: 113 DEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHL 172 D +E L RA F A W NVQP+SGS AN+AVY AL++P D +MG+DL GGHL Sbjct: 68 DRVESLAIERAKALFG---AAWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123 Query: 173 THGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI 232 THG R++ + ++ + Y + P T LID ++ A RP++I+AG SAY R Sbjct: 124 THG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFW 178 Query: 233 DYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFY 292 D+ RE+ DEV A+L+ DMAH +GLVAA + P+P +A +VT+TTHKTLRG R GLI Sbjct: 179 DFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL- 237 Query: 293 RKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSL 352 + DP+ G+ RI+ +FP +QGGP H IA AVA +A P F+EYS Sbjct: 238 -----SNDPELGK--------RIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSR 284 Query: 353 QVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTC 412 V++NA+ +A+ L RGY +V+GGTDNHL LVDLRPKGL G AE L+ V IT NKN Sbjct: 285 LVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAI 344 Query: 413 PGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSF 471 P D + G+R+G PA+T+R F ++ V + ID ++ Sbjct: 345 PFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELID-------------------RAL 385 Query: 472 LLKDSETSQRLANLRQRVEQFARAFPMP 499 L SE LR+ V + A A PMP Sbjct: 386 LEGPSEA------LREEVRRLALAHPMP 407 >1YJS-A nrPDB Length = 419 Score = 363 bits (931), Expect = e-100, Method: Compositional matrix adjust. Identities = 197/442 (44%), Positives = 275/442 (62%), Gaps = 46/442 (10%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L DP+++ +++E+ RQ +ELIASENF SRA +EA GS L NKY+EGYPG+RYYGG Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E VD +E L + RA + F + A NVQP+SG+ AN+AVY +L+ D ++G++L Sbjct: 64 CEYVDIVEELARERAKQLFGAEHA----NVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG ++ + + + + Y ++P+T +IDY+ + ARL RP+LI+A SAY Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAAASAY 174 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R+ID+A+ RE+ DEV A+L+ DMAHI+GLVAA + P+P +A VTTTTH+TLRG R G Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGG 234 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +I ++ F +I+ A+FP +QGGP H IAA AVA +A F+ Sbjct: 235 MILCQE---------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDDFK 279 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 Y+ +V+ NA+ +A AL G++LVSGGTDNHL+LVDLRP+ L G AE+VL+ V IT N Sbjct: 280 AYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVN 339 Query: 409 KNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQD 467 KNT P D S G+R+G A+T+R F GLE + A + Sbjct: 340 KNTIPYDPESPFVTSGIRIGTAAVTTRGF------------------GLEEMDEIAAI-- 379 Query: 468 FKSFLLKDSETSQRLANLRQRV 489 +LK+ + Q L RQRV Sbjct: 380 -IGLVLKNVGSEQALEEARQRV 400 >5VMB-A nrPDB Length = 425 Score = 359 bits (921), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 202/453 (44%), Positives = 277/453 (61%), Gaps = 46/453 (10%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 S+S+ DPE+ + + E +RQ +ELIASEN+CS A +EA GS L NKY+EGYPGKRYYG Sbjct: 14 SISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYG 73 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD IE + RA E F D A NVQP++GS AN AVY ALL P D ++G+ L Sbjct: 74 GCEFVDVIEQMAIDRAKELFGADYA----NVQPHAGSQANSAVYLALLNPGDTVLGMSLA 129 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG ++S + + ++ Y LN +TG IDY ++ A +PR+I+AG SA Sbjct: 130 HGGHLTHG-----AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSA 184 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y+R++D+ R R++ D+V A+L DMAH++GLVAA V P+P + AD+ TTTTHKTLRG RS Sbjct: 185 YSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRS 244 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI K EI E ++ AVFP QGGP HAIAA A+ K+A + F Sbjct: 245 GLIL---------AKANEEI----EKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDF 291 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y QV+KNA+AMA+ + RGY +VSGGTDNHL L+ L + + G A+ L IT Sbjct: 292 KAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITV 351 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQ 466 NKN+ P D RS G+R+G PA+T+R F E + R + +I + + Sbjct: 352 NKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADVI-------------- 397 Query: 467 DFKSFLLKDSETSQR-LANLRQRVEQFARAFPM 498 DS+ ++ +A+++ +VE FP+ Sbjct: 398 --------DSKGDEKVIADVKAKVEAVCAKFPV 422 >3H7F-A nrPDB Length = 447 Score = 357 bits (915), Expect = 8e-99, Method: Compositional matrix adjust. Identities = 208/456 (45%), Positives = 269/456 (58%), Gaps = 52/456 (11%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L++ DP++ ELL +E RQ LE+IASENF RA L+A GS L NKY+EG PG+RYYGG Sbjct: 26 LAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYGG 85 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E VD +E L + RA F + A NVQP+SG+ AN AV AL+ P +R++GLDL + Sbjct: 86 CEHVDVVENLARDRAKALFGAEFA----NVQPHSGAQANAAVLHALMSPGERLLGLDLAN 141 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG R++ + +E+ Y ++P T LID + + TA FRP++IIAG SAY Sbjct: 142 GGHLTHGM-----RLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSAY 196 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R++D+A R + DEV A LL DMAH +GLVAA + PSP HAD+V+TT HKTL G RSG Sbjct: 197 PRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRSG 256 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 LI ++ + IN AVFP QGGP H IA AVALK A TP F Sbjct: 257 LIVGKQ---------------QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEFA 301 Query: 349 EYSLQVLKNARAMADALL-----ERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403 + + L AR +AD L+ + G S+VSGGTD HLVLVDLR LDG AE +L V Sbjct: 302 DRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHEV 361 Query: 404 SITANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT 462 IT N+N P D R + GLR+G PAL +R F + +F V D I + G Sbjct: 362 GITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATG------- 414 Query: 463 AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 +S ++ L+ R + ARAFP+ Sbjct: 415 ---------------SSVDVSALKDRATRLARAFPL 435 >3GBX-A nrPDB Length = 420 Score = 353 bits (905), Expect = 1e-97, Method: Compositional matrix adjust. Identities = 193/402 (48%), Positives = 264/402 (65%), Gaps = 23/402 (5%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 +++D D E+W+ +++EK RQ +ELIASEN+ S ++A GS L NKY+EGYPGKRYYG Sbjct: 10 NIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYG 69 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD +E L RA E F D A NVQP+SGS AN AVYTALLQP D ++G++L Sbjct: 70 GCEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLQPGDTVLGMNLA 125 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG ++ + + +PY ++ ++G IDY+++A A+ +P++II G SA Sbjct: 126 QGGHLTHG-----SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSA 179 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y+ ++D+A+MRE+ D + A+L DMAH++GL+AA V P+P HA +VTTTTHKTL G R Sbjct: 180 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 239 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI K G E Y ++N AVFPS QGGP H IA AVALK+A P F Sbjct: 240 GLIL---------AKGGDEELYK---KLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEF 287 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y QV KNA+AM + L RGY +VSGGT+NHL L+DL K L G A+ L +IT Sbjct: 288 KVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITV 347 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFI 448 NKN+ P D +S G+R+G+PA+T R F+E + + + ++ Sbjct: 348 NKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 389 >3N0L-A nrPDB Length = 417 Score = 352 bits (904), Expect = 2e-97, Method: Compositional matrix adjust. Identities = 195/450 (43%), Positives = 267/450 (59%), Gaps = 46/450 (10%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 SL D E+++L +E +RQC GLE+IASENF +E +GS L NKY+EGYPGKRYYG Sbjct: 5 SLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRYYG 64 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VDEIE L R + F+ A NVQP SGS AN VY AL+ P D+I+G+DL Sbjct: 65 GCEFVDEIETLAIERCKKLFNCKFA----NVQPNSGSQANQGVYAALINPGDKILGMDLS 120 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG ++S++ +ES Y + G IDY ++ A+ +P+LI+ G SA Sbjct: 121 HGGHLTHG-----AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGASA 174 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 YAR+ID+A+ RE+ DE+ A+L AD+AHI+GLV A PSPF +A +V++TTHKTLRG R Sbjct: 175 YARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGPRG 234 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 G+I D + + +IN A+FP +QGGP H IAA AV K + + Sbjct: 235 GIIMTN------DEELAK--------KINSAIFPGIQGGPLMHVIAAKAVGFKFNLSDEW 280 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y+ QV NA+ +A+ L++R + LVS GTDNHLVL+ + G A+ L ITA Sbjct: 281 KVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGITA 340 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQ 466 NKNT PG+ RS GLRLG PALT+R F+E + V ++I + Sbjct: 341 NKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYIAD---------------- 384 Query: 467 DFKSFLLKDSETSQRLANLRQRVEQFARAF 496 +L D + N++Q +++ A F Sbjct: 385 -----ILDDVNNEKLQENIKQELKKLASNF 409 >4J5U-A nrPDB Length = 420 Score = 351 bits (900), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 193/409 (47%), Positives = 255/409 (62%), Gaps = 28/409 (6%) Query: 46 QESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRY 105 +L ++D E+ E+++ EK RQ +ELIASENF S A LEA G+ L NKY+EGYP KR+ Sbjct: 5 NNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRF 64 Query: 106 YGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLD 165 Y G E VD+ E L R + F+ A NVQP+SGS AN AVY ALLQP D ++G+ Sbjct: 65 YNGCEEVDKAENLAIERVKKLFNCKYA----NVQPHSGSQANQAVYLALLQPGDTVLGMS 120 Query: 166 LPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGT 225 L GGHLTHG ++ + +F ++ Y +N +T LIDY+++ A L +P+L+IAG Sbjct: 121 LDSGGHLTHGAAPNM-----SGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGF 175 Query: 226 SAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGA 285 SAY R ID+A+ RE+ D+V A+ +AD+AHI+GLVA SP +A VT+TTHKTLRG Sbjct: 176 SAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGP 235 Query: 286 RSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTP 345 R GLI D + G +IN A+FP LQGGP H IAA AVA + P Sbjct: 236 RGGLILSN------DEEIGH--------KINSALFPGLQGGPLMHIIAAKAVAFLENLQP 281 Query: 346 MFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSI 405 ++ Y QV+ NA+A+A +L ERGY +++GGTDNH+VLVDLR G+ G A L+ I Sbjct: 282 EYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGI 341 Query: 406 TANKNTCPGDR-SAITPGGLRLGAPALTSRQFREDDF----RRVVDFID 449 T NKN P D S G+RLG PA T+R F+E DF V D +D Sbjct: 342 TCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMVADILD 390 >3G8M-A nrPDB Length = 417 Score = 349 bits (896), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 195/402 (48%), Positives = 259/402 (64%), Gaps = 23/402 (5%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 +++D D E+W+ +++EK RQ +ELIASEN+ S ++A GS L NK++EGYPGKRYYG Sbjct: 7 NIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKFAEGYPGKRYYG 66 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD +E L RA E F D A NVQP+SGS AN AVYTALL+P D ++G++L Sbjct: 67 GCEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLA 122 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG ++ + + +PY ++ TG IDY L A+ +P++II G SA Sbjct: 123 HGGHLTHG-----SPVNFSGKLYNIVPYGID-ATGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y+ ++D+A+MRE+ D + A+L DMAH++GLVAA V P+P HA +VTTTTHKTL G R Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI K G E Y ++N AVFP QGGP H IA AVALK+A P F Sbjct: 237 GLIL---------AKGGSEELYK---KLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEF 284 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y QV KNA+AM + LERGY +VSGGTDNHL LVDL K L G A+ L +IT Sbjct: 285 KTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITV 344 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFI 448 NKN+ P D +S G+R+G PA+T R F+E + + + ++ Sbjct: 345 NKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386 >3PGY-A nrPDB Length = 415 Score = 349 bits (896), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 189/452 (41%), Positives = 264/452 (58%), Gaps = 47/452 (10%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 ++ D + E ++RE RQ +ELIASENF S A +EA GS L NKY+EGYPG+RYYGG Sbjct: 7 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 66 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E VD E + RA F + VNVQP+SG AN+AVY L+ D ++G++L Sbjct: 67 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGPQANMAVYLVALEMGDTVLGMNLSH 122 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG ++ + F+ + Y ++ T I+Y+++ A +P+LI+AG SAY Sbjct: 123 GGHLTHG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAY 177 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 +R ID+ + +E+ DEV A L+ DMAHI+GLVAA + P+P ++AD VTTTTHKTLRG R G Sbjct: 178 SRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 237 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +I ++ ++ I+ +FP +QGGP H IAA AVA +A F+ Sbjct: 238 MILCKE---------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFK 282 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPK-GLDGARAERVLELVSITA 407 Y QV+KNA+ +A+AL+ G+ +VSGGTDNHLV VD++ GL G AE L+ V IT Sbjct: 283 TYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITC 342 Query: 408 NKNTCPGDRSA-ITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQ 466 NKNT P D+ G+RLG PA T+R F E F V I Sbjct: 343 NKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII------------------ 384 Query: 467 DFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 S LK+S+ ++L ++RV + +P+ Sbjct: 385 ---SLALKNSKDEEKLQQAKERVAKLTAEYPL 413 >4P3M-A nrPDB Length = 429 Score = 348 bits (893), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 186/388 (47%), Positives = 238/388 (61%), Gaps = 23/388 (5%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 +++D DPE+W+ + E RQ +ELIASEN+ S +EA GS L NKY+EGYPGKRYYG Sbjct: 7 NIADYDPELWQSITDEVQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYG 66 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD E L RA F D A NVQP+SGS AN AVY AL P D I+G+ L Sbjct: 67 GCEYVDVAESLAIERAKSLFGADYA----NVQPHSGSQANAAVYQALCAPGDTILGMSLA 122 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG +S + + ++ Y + P+TG++DY ++ A +P +IIAG SA Sbjct: 123 HGGHLTHG-----SHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSA 177 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y+ ++D+A+ RE+ D+V A+L DMAH++GLVAA + P+P AD+VTTTTHKTL G R Sbjct: 178 YSGIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKTLGGPRG 237 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI + E ++N AVFP QGGP H IAA AVA K+ P F Sbjct: 238 GLILAKAN-------------EAIEKKLNSAVFPGQQGGPLMHVIAAKAVAFKECAEPEF 284 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 Y QVL NA+AM + L RGY +VSGGT+NHL LVDL + + G A+ L IT Sbjct: 285 AVYQQQVLDNAKAMVKSFLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALGNAHITV 344 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSR 434 NKN+ P D RS GLR+G PAL R Sbjct: 345 NKNSVPNDPRSPFVTSGLRIGTPALARR 372 >4WXB-A nrPDB Length = 428 Score = 345 bits (885), Expect = 3e-95, Method: Compositional matrix adjust. Identities = 196/455 (43%), Positives = 272/455 (59%), Gaps = 46/455 (10%) Query: 46 QESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRY 105 +E DPE+W + E +RQ +ELIASEN S+A + A G+ L NKY+EGYPGKRY Sbjct: 17 KEDYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRY 76 Query: 106 YGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLD 165 YGG V+D +E L RA + F A NVQP+SGS AN AVY +L+QP D +MG+D Sbjct: 77 YGGTAVIDVVETLAIERAKKLFGAKFA----NVQPHSGSQANAAVYMSLIQPGDTVMGMD 132 Query: 166 LPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGT 225 L GGHLTHG +S + + + Y ++ ++ L+DY+ + A+ RP+LI+AG Sbjct: 133 LSAGGHLTHG-----APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGA 187 Query: 226 SAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGA 285 SAY+R+ID+A+ RE+ D V A+L+ DMAHI+GLVA+ PSP +A + TTTTHKTLRG Sbjct: 188 SAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGP 247 Query: 286 RSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTP 345 R GLI T E ++N AVFP LQGGP H IAA AVALK+A P Sbjct: 248 RGGLIL-----------TDDE---DIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDP 293 Query: 346 MFREYSLQVLKNARAMADALLER-GYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVS 404 F+EY V+KNA AMAD + + ++SGGT+NHL LVD+ +G A+ VLE V+ Sbjct: 294 AFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVN 353 Query: 405 ITANKNTCPGDR-SAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTA 463 IT NKN+ P ++ S G+R+G+PA+TSR E + R++ +++ E Sbjct: 354 ITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEA------------ 401 Query: 464 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 L++ + + L +R V+ AFP+ Sbjct: 402 ---------LENHDKPEVLERIRGDVKVLTDAFPL 427 >3ECD-A nrPDB Length = 425 Score = 339 bits (869), Expect = 2e-93, Method: Compositional matrix adjust. Identities = 193/406 (47%), Positives = 249/406 (61%), Gaps = 26/406 (6%) Query: 47 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYY 106 +SL++ D + + +E +RQ +ELIASEN SRA L+A GS L NKY+EGYPGKRYY Sbjct: 11 QSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAEGYPGKRYY 70 Query: 107 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 166 GG E DE+E L R F+ A NVQP+SG+ AN AV AL +P D ++G+ L Sbjct: 71 GGCEFADEVEALAIERVKRLFNAGHA----NVQPHSGAQANGAVMLALAKPGDTVLGMSL 126 Query: 167 PDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTS 226 GGHLTHG + + + +F ++ Y ++ T LIDY+Q+ A+ +P LIIAG S Sbjct: 127 DAGGHLTHG-----AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKPSLIIAGFS 181 Query: 227 AYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGAR 286 AY R +D+AR R + D V A L+ DMAHI+G++AA +P +HA +VT+TTHKTLRG R Sbjct: 182 AYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTTHKTLRGPR 241 Query: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346 G + EI +IN AVFP LQGGP H IA AVA +A T Sbjct: 242 GGFVLTND----------EEIA----KKINSAVFPGLQGGPLMHVIAGKAVAFGEALTDD 287 Query: 347 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 406 F+ Y +VL NA+A+ D L G LV+GGTDNHL+LVDLRPKGL GA+ E+ LE IT Sbjct: 288 FKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQALERAGIT 347 Query: 407 ANKNTCPGD--RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDE 450 NKN P D + IT G+RLG PA T+R F +FR V I E Sbjct: 348 CNKNGIPFDPEKPTITS-GIRLGTPAGTTRGFGAAEFREVGRLILE 392 >4OTL-A nrPDB Length = 423 Score = 332 bits (850), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 186/454 (40%), Positives = 265/454 (58%), Gaps = 47/454 (10%) Query: 46 QESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRY 105 Q ++++ DPE++ +++E RQ +ELIASEN+ S A + A GS L NKY+EGYPGKRY Sbjct: 14 QSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRY 73 Query: 106 YGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLD 165 YGG E VD +E L R + F + A NVQP SGS AN V+ A+L+P D IMG+ Sbjct: 74 YGGCEYVDVVEQLAIDRVKQLFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMS 129 Query: 166 LPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGT 225 L GGHLTHG ++ + +F + Y LN IDY+ A +P+LI+AG Sbjct: 130 LAHGGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYDAAEKLANEHKPKLIVAGA 183 Query: 226 SAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGA 285 SA+A ID+ R+ ++ V A+L+ DMAH +GL+AA V P+P HAD VTTTTHK+LRG Sbjct: 184 SAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGP 243 Query: 286 RSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTP 345 R G+I + +E IN A+FP +QGGP H IAA AVA K+A +P Sbjct: 244 RGGVILMKA---------------EYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSP 288 Query: 346 MFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSI 405 F+EY +V++NAR +A+ L++RG +VSG T++H++LVDLR K + G AE L I Sbjct: 289 EFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHI 348 Query: 406 TANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAK 464 T NKN P D G+RLG+PA+T+R F + +V + I + Sbjct: 349 TVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIAD-------------- 394 Query: 465 LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 +L++ E + + +R +V + + FP+ Sbjct: 395 -------VLENPEDAATIERVRAQVAELTKRFPV 421 >5VC2-A nrPDB Length = 424 Score = 323 bits (828), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 181/418 (43%), Positives = 248/418 (59%), Gaps = 29/418 (6%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L +D E++EL+ E RQ LE+IASEN+ + +EA+GS L NKY+EGYP KRYYGG Sbjct: 13 LEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKRYYGG 72 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 EVVD+IE L RA + F+ A NVQ +SGS AN AVY ALL+P+D+I+G+DL Sbjct: 73 CEVVDKIESLAIERAKKLFNCQFA----NVQAHSGSQANNAVYHALLKPYDKILGMDLSC 128 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG ++S T ++S Y +N G IDY + A+ +P +I+ G SAY Sbjct: 129 GGHLTHG-----AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCGFSAY 182 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R ID+ + RE+ DEV A LL D+AH++GLV PF H +V++TTHKTLRG R G Sbjct: 183 PREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRGPRGG 242 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +I EI +I+ A+FP QGGP H IAA AV K+ P F+ Sbjct: 243 IIL----------TNDEEIA----AKIDKAIFPGTQGGPLMHVIAAKAVGFKENLKPEFK 288 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 Y+ V N + +A AL E+ + LVSGGT NHL+L+D K G A+ L IT N Sbjct: 289 AYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVN 348 Query: 409 KNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFR----RVVDFIDEGVNIGLEVKSK 461 KNT PG+ RS G+R+G+ AL++R +F ++ D +++ N+ L++ K Sbjct: 349 KNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLHVK 406 >4BHD-A nrPDB Length = 428 Score = 186 bits (473), Expect = 1e-47, Method: Compositional matrix adjust. Identities = 131/414 (31%), Positives = 206/414 (49%), Gaps = 41/414 (9%) Query: 69 RGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFD 128 ++LIASEN S A EA + ++Y+EG PGKR Y G + +DE+E LC + E F Sbjct: 22 ESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEVETLCIELSKELFK 81 Query: 129 LDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSI 188 + A NVQP SG ANLAV+ A +P D++M L +PDGGH++H ++SA I Sbjct: 82 AEHA----NVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHW------KVSAAGI 131 Query: 189 -FFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAH 247 + + + +P+ ID + + +P+LI+ G S + A E EV A Sbjct: 132 RGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPVADAYEAAQEVGAK 191 Query: 248 LLADMAHISGLVAAKVIPSPFKH-ADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGRE 306 + D AH+ GL+A K P + A+ + +THKT G + G+I K Sbjct: 192 IAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTTK------------ 239 Query: 307 IPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFRE-YSLQVLKNARAMADAL 365 D+I+ VFP + H H A +A+AL + F E Y+ QV+KNA+A+A AL Sbjct: 240 ---ENADKIDSHVFPGVVSNHHLHHKAGLAIALAEMLE--FGEAYAKQVIKNAKALAQAL 294 Query: 366 LERGYSLV---SGGTDNHLVLVDLRPK---GLDGARAERVLELVSITANKNTCPGD--RS 417 ERG++++ T++H V++D+ + ++ E +I NKN P D + Sbjct: 295 YERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANIILNKNLLPWDDVNN 354 Query: 418 AITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFKSF 471 + P G+RLG T +E + + +F+ I ++ + +D K F Sbjct: 355 SDNPSGIRLGTQECTRLGMKEKEMEEIAEFMK---RIAIDKEKPEKVREDVKEF 405 >5XNI-A nrPDB Length = 260 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 26/45 (57%), Gaps = 2/45 (4%) Query: 352 LQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARA 396 L +L++ A+ + R Y +SG T+ HL+ L+ KG+D +A Sbjct: 182 LSILRDIEALLEKYNTRSY--ISGSTEFHLLTKSLKLKGIDSIKA 224 >3TC3-A nrPDB Length = 310 Score = 29.6 bits (65), Expect = 3.1, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 26/47 (55%), Gaps = 5/47 (10%) Query: 415 DRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSK 461 D S PG P + + E++FRR V+ +DE V+I LEVK K Sbjct: 251 DYSEQEPGE----KPGVHATTINEENFRRFVNEVDE-VDIMLEVKDK 292 >2DC1-A nrPDB Length = 236 Score = 28.9 bits (63), Expect = 5.0, Method: Compositional matrix adjust. Identities = 35/123 (28%), Positives = 50/123 (40%), Gaps = 14/123 (11%) Query: 205 DYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVI 264 DY + L A + LI+ T A+A +R+REVC + + I GL A I Sbjct: 65 DYAEKILKAGI---DLIVLSTGAFADRDFLSRVREVCRKTGRRVYIASGAIGGLDA---I 118 Query: 265 PSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQ 324 S + + + TT K R F RKGV + + E F +N A S+ Sbjct: 119 FSASELIEEIVLTTRKNWRQ------FGRKGV--IFEGSASEAAQKFPKNLNVAATLSIA 170 Query: 325 GGP 327 G Sbjct: 171 SGK 173 >2DPD-A nrPDB Length = 122 Score = 28.1 bits (61), Expect = 9.9, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 25/40 (62%) Query: 441 FRRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQ 480 +R + + +D+G+ ++VK + AKLQ+ + KD E ++ Sbjct: 58 YRSLHELLDDGILKQIKVKKEGAKLQEVVLYQFKDYEAAK 97 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5X3V-A nrPDB 772 0.0 1RVY-A nrPDB 686 0.0 1BJ4-A nrPDB 680 0.0 1EJI-A nrPDB 677 0.0 6CCZ-A nrPDB 655 0.0 5Z0Y-A nrPDB 647 0.0 4O6Z-A nrPDB 617 e-177 5XMU-A nrPDB 617 e-177 4J5U-A nrPDB 594 e-170 4P3M-A nrPDB 594 e-170 5VMB-A nrPDB 593 e-170 3N0L-A nrPDB 593 e-170 1YJS-A nrPDB 592 e-169 2DKJ-A nrPDB 590 e-169 3PGY-A nrPDB 588 e-168 3GBX-A nrPDB 577 e-165 3G8M-A nrPDB 573 e-164 4OTL-A nrPDB 571 e-163 3ECD-A nrPDB 570 e-163 4WXB-A nrPDB 561 e-160 5VC2-A nrPDB 558 e-159 3H7F-A nrPDB 552 e-157 4BHD-A nrPDB 439 e-123 Sequences not found previously or not previously below threshold: 3TQX-A nrPDB 52 4e-07 1M6S-A nrPDB 44 1e-04 3WY7-A nrPDB 42 0.001 2X8U-A nrPDB 41 0.001 3A2B-A nrPDB 40 0.002 1CS1-A nrPDB 40 0.002 1FC4-A nrPDB 39 0.004 2AEV-A nrPDB 38 0.011 3OP7-A nrPDB 37 0.014 2OKK-A nrPDB 37 0.014 2BWN-A nrPDB 37 0.028 3NNK-A nrPDB 35 0.074 3BB8-A nrPDB 34 0.17 5XT5-A nrPDB 34 0.25 6NPB-A nrPDB 33 0.26 6ONN-A nrPDB 32 0.47 1GC4-A nrPDB 32 0.76 2OKJ-A nrPDB 32 0.78 2OGE-A nrPDB 32 0.84 5HH9-A nrPDB 31 1.0 1XI9-A nrPDB 31 1.0 3TRI-A nrPDB 31 1.1 3Q8X-B nrPDB 31 1.2 5JAY-A nrPDB 30 1.6 5O5C-A nrPDB 30 1.8 3WPR-A nrPDB 30 2.1 5TXT-B nrPDB 30 2.2 5W70-A nrPDB 30 2.5 3W1J-A nrPDB 30 2.5 3W1H-A nrPDB 30 2.5 3WPA-A nrPDB 30 2.8 5JWG-A nrPDB 30 2.9 1RVG-A nrPDB 30 3.1 2YWH-A nrPDB 29 4.0 3WGB-A nrPDB 29 4.1 2D1S-A nrPDB 29 4.6 2FJK-A nrPDB 29 5.8 1XNG-A nrPDB 29 6.2 6C9E-A nrPDB 28 8.9 3ZX6-A nrPDB 28 9.3 >5X3V-A nrPDB Length = 496 Score = 772 bits (1994), Expect = 0.0, Method: Composition-based stats. Identities = 482/483 (99%), Positives = 483/483 (100%) Query: 22 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS 81 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS Sbjct: 1 MAIRAQHSNAAQTQTGEANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCS 60 Query: 82 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY 141 RAALEALGSCLNN+YSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY Sbjct: 61 RAALEALGSCLNNRYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY 120 Query: 142 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 201 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT Sbjct: 121 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 180 Query: 202 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA 261 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA Sbjct: 181 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAA 240 Query: 262 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP 321 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP Sbjct: 241 KVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFP 300 Query: 322 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL 381 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL Sbjct: 301 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHL 360 Query: 382 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF 441 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF Sbjct: 361 VLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDF 420 Query: 442 RRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 RRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF Sbjct: 421 RRVVDFIDEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 480 Query: 502 DEH 504 DEH Sbjct: 481 DEH 483 >1RVY-A nrPDB Length = 483 Score = 686 bits (1771), Expect = 0.0, Method: Composition-based stats. Identities = 300/467 (64%), Positives = 367/467 (78%), Gaps = 8/467 (1%) Query: 43 WTGQE-----SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYS 97 W+ E L DSD E+++++++E +RQ GLELIASENF SRA LEALGSCLNNKYS Sbjct: 14 WSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 73 Query: 98 EGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQP 157 +GYPG+RYYGG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++P Sbjct: 74 QGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPANFAVYTALVEP 133 Query: 158 HDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFR 217 H RIMGLDLPDGGHLTHG+M+D K+ISATSIFFESM YK+NP TG IDY++L ARLF Sbjct: 134 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYDRLEENARLFH 193 Query: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 P+LIIAGTS Y+R +DY R+R++ DE A+L+ADMAHISGLV A V+PSPF+H +VTTT Sbjct: 194 PKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSPFEHCHVVTTT 253 Query: 278 THKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAV 337 THKTLRG R+G+IFYR+GV++VDPKTG+EI Y E IN AVFP LQGGPHNHAIA VAV Sbjct: 254 THKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 313 Query: 338 ALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAE 397 ALKQA TP F+EY QV+ N RA++ AL+E GY +V+GG+DNHL+LVDLR KG DG RAE Sbjct: 314 ALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 373 Query: 398 RVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 +VLE SI NKNTCPGD+SA+ P GLRLG PALTSR E DF++V FI G+ + ++ Sbjct: 374 KVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTVQ 433 Query: 458 VKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 ++ T A L++FK L D + + + LRQ VE FA FP+PG Sbjct: 434 IQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGL 480 >1BJ4-A nrPDB Length = 470 Score = 680 bits (1754), Expect = 0.0, Method: Composition-based stats. Identities = 303/467 (64%), Positives = 366/467 (78%), Gaps = 9/467 (1%) Query: 43 WTGQ-----ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYS 97 W+ + L DSD E++ ++++E +RQ GLELIASENF SRA LEALGSCLNNKYS Sbjct: 5 WSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 64 Query: 98 EGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQP 157 EGYPG+RYYGG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++P Sbjct: 65 EGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEP 124 Query: 158 HDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFR 217 H RIMGLDLPDGGHLTHG+M+D K+ISATSIFFESMPYK+NP TG I+Y+QL ARLF Sbjct: 125 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFH 184 Query: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 P+LIIAGTS Y+R ++YAR+R++ DE A+L+ADMAHISGLVAA V+PSPF+H +VTTT Sbjct: 185 PKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 244 Query: 278 THKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAV 337 THKTLRG R+G+IFYRKGVK+VDP TG+EI Y E IN AVFP LQGGPHNHAIA VAV Sbjct: 245 THKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 304 Query: 338 ALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAE 397 ALKQA T F+ Y QV+ N RA+++AL E GY +V+GG+DNHL+LVDLR KG DG RAE Sbjct: 305 ALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 364 Query: 398 RVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 +VLE SI NKNTCPGDRSA+ P GLRLG PALTSR E DF++V FI G+ + L+ Sbjct: 365 KVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQ 424 Query: 458 VKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 501 ++S T A L++FK L D + + LR+ VE FA FP+PG Sbjct: 425 IQSDTGVAATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGL 470 >1EJI-A nrPDB Length = 478 Score = 677 bits (1748), Expect = 0.0, Method: Composition-based stats. Identities = 300/469 (63%), Positives = 366/469 (78%), Gaps = 8/469 (1%) Query: 43 WTGQE-----SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYS 97 W E L DSD E++ ++++E +RQ GLELIASENF SRA LEALGS LNNKYS Sbjct: 9 WASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGSSLNNKYS 68 Query: 98 EGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQP 157 EGYPG+RYYGG E +DE+E+LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++P Sbjct: 69 EGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAVYTALVEP 128 Query: 158 HDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFR 217 H RIMGLDLPDGGHLTHG+M+D K+ISATSIFFESMPYK+ P+TG I+Y+QL A LF Sbjct: 129 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLEENASLFH 188 Query: 218 PRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTT 277 P+LIIAGTS Y+R +DYAR+R++ D+ A+L+ADMAHISGLVAA V+PSPF+H +VTTT Sbjct: 189 PKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 248 Query: 278 THKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAV 337 THKTLRG R+G+IFYRKGV++VDPKTG+E Y E IN AVFP LQGGPHNHAIA VAV Sbjct: 249 THKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNHAIAGVAV 308 Query: 338 ALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAE 397 ALKQA T F+ Y LQVL N RA++DAL E GY +V+GG+DNHL+L+DLR KG DG RAE Sbjct: 309 ALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKGTDGGRAE 368 Query: 398 RVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 +VLE SI NKNTCPGD+SA+ P GLRLG PALTSR E+DF++V FI G+ + L+ Sbjct: 369 KVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHRGIELTLQ 428 Query: 458 VKSKT---AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFDE 503 ++S A L++FK L D + +A LR+ VE FA F +PG + Sbjct: 429 IQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPD 477 >6CCZ-A nrPDB Length = 455 Score = 655 bits (1689), Expect = 0.0, Method: Composition-based stats. Identities = 267/456 (58%), Positives = 340/456 (74%), Gaps = 12/456 (2%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 LS++DP++ ++ +EKDRQ R LELIASENF S+A +EA+GSCL NKYSEG PGKRYYGG Sbjct: 9 LSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGG 68 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E +DE+E+LCQ+RAL AF LD +WGVNVQP SGSPAN AVYTA+L+PHDRIMGLDLP Sbjct: 69 NEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPH 128 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHL+HG+M+ +R+S TSI+FESMPY+L+ TG+IDY+ L TA LFRP+LIIAG SAY Sbjct: 129 GGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAY 188 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R IDYAR R++ D V A L+ DMAH+SGL+AA V+ PF+ DIVTTTTHK+LRG R G Sbjct: 189 PRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGG 248 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +IF++K E IN AVFP LQGGPHNH I +AV LK A +P F+ Sbjct: 249 MIFFKKDAVHG---------VDLESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDFK 299 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 Y QV+ N RA+A+ L+E Y LVSGG+DNHLVLVDLRP G+DGAR E++L++ SIT N Sbjct: 300 NYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITLN 359 Query: 409 KNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTA--KLQ 466 KN+ PGD+SA+ PGG+R+G+PA+T+R E +F + D I EGV I LE KS + K+Q Sbjct: 360 KNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKVQ 419 Query: 467 DFKSFLLKDS-ETSQRLANLRQRVEQFARAFPMPGF 501 DF +F+L +++NLR++VE A +P+PG Sbjct: 420 DFLNFVLAPEFPLGDKVSNLRRKVEALATQYPIPGV 455 >5Z0Y-A nrPDB Length = 470 Score = 647 bits (1670), Expect = 0.0, Method: Composition-based stats. Identities = 257/454 (56%), Positives = 350/454 (77%), Gaps = 7/454 (1%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L+++DPE+ ++++ E DRQ + LIASENF S + +ALG+ + NKYSEGYPG RYYGG Sbjct: 18 LAETDPEVNQIIKDEVDRQKHSIVLIASENFTSTSVFDALGTPMCNKYSEGYPGARYYGG 77 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E +D +E+LCQ+RAL+AF LD ++WGVNVQ SGSPANL VY A+++PHDR+MGLDLP Sbjct: 78 NEHIDRMEILCQQRALKAFHLDGSRWGVNVQTLSGSPANLQVYQAIMKPHDRLMGLDLPH 137 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHL+HGY +D ++ISA S +FE+MPY+++ +TG+IDY+ L TA L+RP++++AGTSAY Sbjct: 138 GGHLSHGYQTDTRKISAVSTYFETMPYRVDLETGIIDYDMLEKTAVLYRPKVLVAGTSAY 197 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 RLIDY RMRE+ D+V A+L+ DMAHISGL+AA VIPSPF++ADIVTTTTHK+LRG R Sbjct: 198 CRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTTTTHKSLRGPRGA 257 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +IF+RKGV++V+PKTG+EI Y E+ INF+VFP QGGPHNH IAA+A ALKQA TP F+ Sbjct: 258 MIFFRKGVRSVNPKTGKEIYYDLENPINFSVFPGHQGGPHNHTIAALATALKQAATPEFK 317 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 +Y QVLKNA+A+ + GY LVS GTD+H+VLV L+ K +DGAR E V E ++I N Sbjct: 318 QYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGARIETVCENINIALN 377 Query: 409 KNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKS----KTAK 464 KN+ PGDRSA+ PGG+R+GAPA+T+R E+DF ++ ++ID+ V +V+S + K Sbjct: 378 KNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYAKKVQSELPIEANK 437 Query: 465 LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 L+DFK+ + +E S + L+ + +A FP+ Sbjct: 438 LKDFKAKI---AEGSDEITQLKNEISAWAGEFPL 468 >4O6Z-A nrPDB Length = 480 Score = 617 bits (1591), Expect = e-177, Method: Composition-based stats. Identities = 207/458 (45%), Positives = 292/458 (63%), Gaps = 17/458 (3%) Query: 42 GWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYP 101 G + L D E+++LL++EK+RQ + LIASEN + A E LG ++NKYSEGYP Sbjct: 38 GMFNNDPLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYP 97 Query: 102 GKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRI 161 KRYYGG + VD+IE LC +RALEAF++ +WGVNVQP SGS AN+ AL+ +I Sbjct: 98 HKRYYGGNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKI 157 Query: 162 MGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLI 221 MG+ L GGHLTHG+ + K++S TS FES YK N + G +D + A F+P++I Sbjct: 158 MGMHLCSGGHLTHGFFDEKKKVSITSDLFESKLYKCNSE-GYVDMESVRNLALSFQPKVI 216 Query: 222 IAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKT 281 I G ++Y R IDY RE+CDEV A+L AD++HIS VA ++ +PF +AD+VTTTTHK Sbjct: 217 ICGYTSYPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKI 276 Query: 282 LRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQ 341 LRG RS LIF+ K + +IN +VFPS QGGPHN+ IAAVA LK+ Sbjct: 277 LRGPRSALIFFNKKRNP-----------GIDQKINSSVFPSFQGGPHNNKIAAVACQLKE 325 Query: 342 ACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLE 401 TP F+EY+ QVL N++A+A+ LL+R LV+ GTDNHL++VDLR + G++ + Sbjct: 326 VNTPEFKEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCN 385 Query: 402 LVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSK 461 ++I NKNT P D ++P G+R+G PALT+R +E D + D + + + + E++ K Sbjct: 386 AINIALNKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQK 445 Query: 462 TA-KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 KL DFK L+ + ++ L++ V Q+A+ P Sbjct: 446 YGKKLVDFKKGLVNNP----KIDELKKEVVQWAKNLPF 479 >5XMU-A nrPDB Length = 442 Score = 617 bits (1590), Expect = e-177, Method: Composition-based stats. Identities = 205/458 (44%), Positives = 291/458 (63%), Gaps = 17/458 (3%) Query: 43 WTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPG 102 E L D E+ ++L E+ RQ + LIASEN + A E LG+ ++NKYSEGYP Sbjct: 1 MFNNEPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSNKYSEGYPK 60 Query: 103 KRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 162 KRYYGG + +D+IE LCQ+RALEAF++ +WGVNVQP SGS AN+ AL+ +IM Sbjct: 61 KRYYGGNDFIDKIEELCQKRALEAFNVSDEEWGVNVQPLSGSAANVQALYALVGVKGKIM 120 Query: 163 GLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLII 222 G+ L GGHLTHG+ + K++S TS FES YK N + G +D + + A F+P++II Sbjct: 121 GMHLCSGGHLTHGFFDEKKKVSITSDMFESKLYKCNSQ-GYVDLDAVREMALSFKPKVII 179 Query: 223 AGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTL 282 G ++Y R IDY + R++CDEV A+L AD++HIS VA ++ +PF HAD+VTTTTHK L Sbjct: 180 CGYTSYPRDIDYQQFRQICDEVNAYLFADISHISSFVACNILNNPFLHADVVTTTTHKIL 239 Query: 283 RGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQA 342 RG RS LIF+ K E +IN AVFPS QGGPHN+ IAAVA LK+ Sbjct: 240 RGPRSALIFFNKKRNP-----------GIEQKINSAVFPSFQGGPHNNKIAAVACQLKEV 288 Query: 343 CTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLEL 402 +P F+EY+ QVL N++A+A AL+ + LV+ GTDNHL++VDLR + G++ + Sbjct: 289 HSPAFKEYTQQVLLNSKALAKALISKQIDLVTNGTDNHLIVVDLRKFSITGSKLQETCNA 348 Query: 403 VSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT 462 ++++ NKNT P D ++P G+R+G PA+T+R +E D + D + + I ++++ + Sbjct: 349 INVSLNKNTIPSDVDCVSPSGVRIGTPAMTTRGAKEKDMEFIADVLARAIKITVDLQEQY 408 Query: 463 A-KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMP 499 KL DFK L +++ L L+Q V +A A P P Sbjct: 409 GKKLVDFKKGLPGNAQ----LQQLKQEVVTWAGALPFP 442 >4J5U-A nrPDB Length = 420 Score = 594 bits (1531), Expect = e-170, Method: Composition-based stats. Identities = 196/456 (42%), Positives = 260/456 (57%), Gaps = 41/456 (8%) Query: 46 QESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRY 105 +L ++D E+ E+++ EK RQ +ELIASENF S A LEA G+ L NKY+EGYP KR+ Sbjct: 5 NNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRF 64 Query: 106 YGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLD 165 Y G E VD+ E L R + F+ A NVQP+SGS AN AVY ALLQP D ++G+ Sbjct: 65 YNGCEEVDKAENLAIERVKKLFNCKYA----NVQPHSGSQANQAVYLALLQPGDTVLGMS 120 Query: 166 LPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGT 225 L GGHLTHG + + +F ++ Y +N +T LIDY+++ A L +P+L+IAG Sbjct: 121 LDSGGHLTHGAAP-----NMSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGF 175 Query: 226 SAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGA 285 SAY R ID+A+ RE+ D+V A+ +AD+AHI+GLVA SP +A VT+TTHKTLRG Sbjct: 176 SAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGP 235 Query: 286 RSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTP 345 R GLI +IN A+FP LQGGP H IAA AVA + P Sbjct: 236 RGGLILSND--------------EEIGHKINSALFPGLQGGPLMHIIAAKAVAFLENLQP 281 Query: 346 MFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSI 405 ++ Y QV+ NA+A+A +L ERGY +++GGTDNH+VLVDLR G+ G A L+ I Sbjct: 282 EYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGI 341 Query: 406 TANKNTCPGDR-SAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAK 464 T NKN P D S G+RLG PA T+R F+E DF V + Sbjct: 342 TCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMVA--------------- 386 Query: 465 LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPG 500 D L + + S + V + FP G Sbjct: 387 --DILDGLKNNEDNSALEQQVLNEVTKLIELFPFYG 420 >4P3M-A nrPDB Length = 429 Score = 594 bits (1531), Expect = e-170, Method: Composition-based stats. Identities = 191/462 (41%), Positives = 260/462 (56%), Gaps = 41/462 (8%) Query: 43 WTGQE-SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYP 101 ++ +++D DPE+W+ + E RQ +ELIASEN+ S +EA GS L NKY+EGYP Sbjct: 1 MFNRDMNIADYDPELWQSITDEVQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYP 60 Query: 102 GKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRI 161 GKRYYGG E VD E L RA F D A NVQP+SGS AN AVY AL P D I Sbjct: 61 GKRYYGGCEYVDVAESLAIERAKSLFGADYA----NVQPHSGSQANAAVYQALCAPGDTI 116 Query: 162 MGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLI 221 +G+ L GGHLTHG +S + + ++ Y + P+TG++DY ++ A +P +I Sbjct: 117 LGMSLAHGGHLTHG-----SHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMI 171 Query: 222 IAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKT 281 IAG SAY+ ++D+A+ RE+ D+V A+L DMAH++GLVAA + P+P AD+VTTTTHKT Sbjct: 172 IAGFSAYSGIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKT 231 Query: 282 LRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQ 341 L G R GLI + E ++N AVFP QGGP H IAA AVA K+ Sbjct: 232 LGGPRGGLILAKAN-------------EAIEKKLNSAVFPGQQGGPLMHVIAAKAVAFKE 278 Query: 342 ACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLE 401 P F Y QVL NA+AM + L RGY +VSGGT+NHL LVDL + + G A+ L Sbjct: 279 CAEPEFAVYQQQVLDNAKAMVKSFLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALG 338 Query: 402 LVSITANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKS 460 IT NKN+ P D RS GLR+G PAL R + ++ Sbjct: 339 NAHITVNKNSVPNDPRSPFVTSGLRIGTPALARRGVNAQQSAELALWM------------ 386 Query: 461 KTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGFD 502 D + +++ + + ++ +V +A P+ G + Sbjct: 387 -----CDVLDAIKDEAKLATTITAVKVKVAALCKACPVYGLE 423 >5VMB-A nrPDB Length = 425 Score = 593 bits (1530), Expect = e-170, Method: Composition-based stats. Identities = 197/457 (43%), Positives = 271/457 (59%), Gaps = 44/457 (9%) Query: 43 WTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPG 102 S+S+ DPE+ + + E +RQ +ELIASEN+CS A +EA GS L NKY+EGYPG Sbjct: 9 MFANISISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPG 68 Query: 103 KRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIM 162 KRYYGG E VD IE + RA E F D A NVQP++GS AN AVY ALL P D ++ Sbjct: 69 KRYYGGCEFVDVIEQMAIDRAKELFGADYA----NVQPHAGSQANSAVYLALLNPGDTVL 124 Query: 163 GLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLII 222 G+ L GGHLTHG ++S + + ++ Y LN +TG IDY ++ A +PR+I+ Sbjct: 125 GMSLAHGGHLTHG-----AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIV 179 Query: 223 AGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTL 282 AG SAY+R++D+ R R++ D+V A+L DMAH++GLVAA V P+P + AD+ TTTTHKTL Sbjct: 180 AGFSAYSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTL 239 Query: 283 RGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQA 342 RG RSGLI + E ++ AVFP QGGP HAIAA A+ K+A Sbjct: 240 RGPRSGLILAKAN-------------EEIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEA 286 Query: 343 CTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLEL 402 + F+ Y QV+KNA+AMA+ + RGY +VSGGTDNHL L+ L + + G A+ L Sbjct: 287 MSDDFKAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGA 346 Query: 403 VSITANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSK 461 IT NKN+ P D RS G+R+G PA+T+R F E + R + +I + + Sbjct: 347 AHITVNKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADVI--------- 397 Query: 462 TAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 + +A+++ +VE FP+ Sbjct: 398 ------------DSKGDEKVIADVKAKVEAVCAKFPV 422 >3N0L-A nrPDB Length = 417 Score = 593 bits (1528), Expect = e-170, Method: Composition-based stats. Identities = 194/454 (42%), Positives = 265/454 (58%), Gaps = 46/454 (10%) Query: 44 TGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGK 103 + SL D E+++L +E +RQC GLE+IASENF +E +GS L NKY+EGYPGK Sbjct: 1 SNAMSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGK 60 Query: 104 RYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMG 163 RYYGG E VDEIE L R + F+ A NVQP SGS AN VY AL+ P D+I+G Sbjct: 61 RYYGGCEFVDEIETLAIERCKKLFNCKFA----NVQPNSGSQANQGVYAALINPGDKILG 116 Query: 164 LDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIA 223 +DL GGHLTHG ++S++ +ES Y + G IDY ++ A+ +P+LI+ Sbjct: 117 MDLSHGGHLTHG-----AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVC 170 Query: 224 GTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLR 283 G SAYAR+ID+A+ RE+ DE+ A+L AD+AHI+GLV A PSPF +A +V++TTHKTLR Sbjct: 171 GASAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLR 230 Query: 284 GARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQAC 343 G R G+I +IN A+FP +QGGP H IAA AV K Sbjct: 231 GPRGGIIMTND--------------EELAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNL 276 Query: 344 TPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELV 403 + ++ Y+ QV NA+ +A+ L++R + LVS GTDNHLVL+ + G A+ L Sbjct: 277 SDEWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNA 336 Query: 404 SITANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT 462 ITANKNT PG+ RS GLRLG PALT+R F+E + V ++I + Sbjct: 337 GITANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYIAD------------ 384 Query: 463 AKLQDFKSFLLKDSETSQRLANLRQRVEQFARAF 496 +L D + N++Q +++ A F Sbjct: 385 ---------ILDDVNNEKLQENIKQELKKLASNF 409 >1YJS-A nrPDB Length = 419 Score = 592 bits (1527), Expect = e-169, Method: Composition-based stats. Identities = 194/447 (43%), Positives = 273/447 (61%), Gaps = 46/447 (10%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L DP+++ +++E+ RQ +ELIASENF SRA +EA GS L NKY+EGYPG+RYYGG Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E VD +E L + RA + F + A NVQP+SG+ AN+AVY +L+ D ++G++L Sbjct: 64 CEYVDIVEELARERAKQLFGAEHA----NVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG ++ + + + + Y ++P+T +IDY+ + ARL RP+LI+A SAY Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAAASAY 174 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R+ID+A+ RE+ DEV A+L+ DMAHI+GLVAA + P+P +A VTTTTH+TLRG R G Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGG 234 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +I ++ F +I+ A+FP +QGGP H IAA AVA +A F+ Sbjct: 235 MILCQE---------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDDFK 279 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 Y+ +V+ NA+ +A AL G++LVSGGTDNHL+LVDLRP+ L G AE+VL+ V IT N Sbjct: 280 AYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVN 339 Query: 409 KNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQD 467 KNT P D S G+R+G A+T+R F ++ + I Sbjct: 340 KNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIAAII------------------- 380 Query: 468 FKSFLLKDSETSQRLANLRQRVEQFAR 494 +LK+ + Q L RQRV Sbjct: 381 --GLVLKNVGSEQALEEARQRVAALTD 405 >2DKJ-A nrPDB Length = 407 Score = 590 bits (1520), Expect = e-169, Method: Composition-based stats. Identities = 199/450 (44%), Positives = 260/450 (57%), Gaps = 49/450 (10%) Query: 51 DSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAE 110 D ++EL+ E+ RQ GLELIASENF S+ EA+GS L NKY+EGYPG RYYGG E Sbjct: 6 KRDEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCE 65 Query: 111 VVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGG 170 V+D +E L RA F A NVQP+SGS AN+AVY AL++P D +MG+DL GG Sbjct: 66 VIDRVESLAIERAKALFGAAWA----NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGG 121 Query: 171 HLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYAR 230 HLTHG R++ + ++ + Y + P T LID ++ A RP++I+AG SAY R Sbjct: 122 HLTHG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPR 176 Query: 231 LIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLI 290 D+ RE+ DEV A+L+ DMAH +GLVAA + P+P +A +VT+TTHKTLRG R GLI Sbjct: 177 FWDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLI 236 Query: 291 FYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREY 350 RI+ +FP +QGGP H IA AVA +A P F+EY Sbjct: 237 LSNDP--------------ELGKRIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEY 282 Query: 351 SLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITANKN 410 S V++NA+ +A+ L RGY +V+GGTDNHL LVDLRPKGL G AE L+ V IT NKN Sbjct: 283 SRLVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKN 342 Query: 411 TCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQDFK 469 P D + G+R+G PA+T+R F ++ V + ID + G Sbjct: 343 AIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRALLEGPS------------ 390 Query: 470 SFLLKDSETSQRLANLRQRVEQFARAFPMP 499 LR+ V + A A PMP Sbjct: 391 -------------EALREEVRRLALAHPMP 407 >3PGY-A nrPDB Length = 415 Score = 588 bits (1515), Expect = e-168, Method: Composition-based stats. Identities = 189/452 (41%), Positives = 264/452 (58%), Gaps = 47/452 (10%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 ++ D + E ++RE RQ +ELIASENF S A +EA GS L NKY+EGYPG+RYYGG Sbjct: 7 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 66 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 E VD E + RA F + VNVQP+SG AN+AVY L+ D ++G++L Sbjct: 67 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGPQANMAVYLVALEMGDTVLGMNLSH 122 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG ++ + F+ + Y ++ T I+Y+++ A +P+LI+AG SAY Sbjct: 123 GGHLTHG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAY 177 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 +R ID+ + +E+ DEV A L+ DMAHI+GLVAA + P+P ++AD VTTTTHKTLRG R G Sbjct: 178 SRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 237 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +I ++ ++ I+ +FP +QGGP H IAA AVA +A F+ Sbjct: 238 MILCKE---------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFK 282 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPK-GLDGARAERVLELVSITA 407 Y QV+KNA+ +A+AL+ G+ +VSGGTDNHLV VD++ GL G AE L+ V IT Sbjct: 283 TYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITC 342 Query: 408 NKNTCPGDRS-AITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQ 466 NKNT P D+ G+RLG PA T+R F E F V I Sbjct: 343 NKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKII------------------ 384 Query: 467 DFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 S LK+S+ ++L ++RV + +P+ Sbjct: 385 ---SLALKNSKDEEKLQQAKERVAKLTAEYPL 413 >3GBX-A nrPDB Length = 420 Score = 577 bits (1487), Expect = e-165, Method: Composition-based stats. Identities = 194/452 (42%), Positives = 274/452 (60%), Gaps = 44/452 (9%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 +++D D E+W+ +++EK RQ +ELIASEN+ S ++A GS L NKY+EGYPGKRYYG Sbjct: 10 NIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYG 69 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD +E L RA E F D A NVQP+SGS AN AVYTALLQP D ++G++L Sbjct: 70 GCEYVDVVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLQPGDTVLGMNLA 125 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG ++ + + +PY ++ ++G IDY+++A A+ +P++II G SA Sbjct: 126 QGGHLTHG-----SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSA 179 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y+ ++D+A+MRE+ D + A+L DMAH++GL+AA V P+P HA +VTTTTHKTL G R Sbjct: 180 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRG 239 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI + G ++N AVFPS QGGP H IA AVALK+A P F Sbjct: 240 GLILAKGGD------------EELYKKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEF 287 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y QV KNA+AM + L RGY +VSGGT+NHL L+DL K L G A+ L +IT Sbjct: 288 KVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITV 347 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQ 466 NKN+ P D +S G+R+G+PA+T R F+E + + + ++ + Sbjct: 348 NKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCD---------------- 391 Query: 467 DFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 +L + + ++ +V FP+ Sbjct: 392 -----VLDNINDEATIERVKAKVLDICARFPV 418 >3G8M-A nrPDB Length = 417 Score = 573 bits (1476), Expect = e-164, Method: Composition-based stats. Identities = 195/452 (43%), Positives = 268/452 (59%), Gaps = 44/452 (9%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 +++D D E+W+ +++EK RQ +ELIASEN+ S ++A GS L NK++EGYPGKRYYG Sbjct: 7 NIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKFAEGYPGKRYYG 66 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD +E L RA E F D A NVQP+SGS AN AVYTALL+P D ++G++L Sbjct: 67 GCEYVDIVEQLAIDRAKELFGADYA----NVQPHSGSQANFAVYTALLEPGDTVLGMNLA 122 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGHLTHG ++ + + +PY ++ TG IDY L A+ +P++II G SA Sbjct: 123 HGGHLTHG-----SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSA 176 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y+ ++D+A+MRE+ D + A+L DMAH++GLVAA V P+P HA +VTTTTHKTL G R Sbjct: 177 YSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRG 236 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI + G ++N AVFP QGGP H IA AVALK+A P F Sbjct: 237 GLILAKGGS------------EELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEF 284 Query: 348 REYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 + Y QV KNA+AM + LERGY +VSGGTDNHL LVDL K L G A+ L +IT Sbjct: 285 KTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITV 344 Query: 408 NKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQ 466 NKN+ P D +S G+R+G PA+T R F+E + + + ++ + Sbjct: 345 NKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCD---------------- 388 Query: 467 DFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 +L + ++ +V +P+ Sbjct: 389 -----VLDSINDEAVIERIKGKVLDICARYPV 415 >4OTL-A nrPDB Length = 423 Score = 571 bits (1472), Expect = e-163, Method: Composition-based stats. Identities = 186/454 (40%), Positives = 265/454 (58%), Gaps = 47/454 (10%) Query: 46 QESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRY 105 Q ++++ DPE++ +++E RQ +ELIASEN+ S A + A GS L NKY+EGYPGKRY Sbjct: 14 QSTIANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRY 73 Query: 106 YGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLD 165 YGG E VD +E L R + F + A NVQP SGS AN V+ A+L+P D IMG+ Sbjct: 74 YGGCEYVDVVEQLAIDRVKQLFGAEAA----NVQPNSGSQANQGVFFAMLKPGDTIMGMS 129 Query: 166 LPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGT 225 L GGHLTHG ++ + +F + Y LN IDY+ A +P+LI+AG Sbjct: 130 LAHGGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYDAAEKLANEHKPKLIVAGA 183 Query: 226 SAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGA 285 SA+A ID+ R+ ++ V A+L+ DMAH +GL+AA V P+P HAD VTTTTHK+LRG Sbjct: 184 SAFALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGP 243 Query: 286 RSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTP 345 R G+I + +E IN A+FP +QGGP H IAA AVA K+A +P Sbjct: 244 RGGVILMKA---------------EYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSP 288 Query: 346 MFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSI 405 F+EY +V++NAR +A+ L++RG +VSG T++H++LVDLR K + G AE L I Sbjct: 289 EFKEYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHI 348 Query: 406 TANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAK 464 T NKN P D G+RLG+PA+T+R F + +V + I + Sbjct: 349 TVNKNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIAD-------------- 394 Query: 465 LQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 +L++ E + + +R +V + + FP+ Sbjct: 395 -------VLENPEDAATIERVRAQVAELTKRFPV 421 >3ECD-A nrPDB Length = 425 Score = 570 bits (1470), Expect = e-163, Method: Composition-based stats. Identities = 194/461 (42%), Positives = 257/461 (55%), Gaps = 40/461 (8%) Query: 39 ANRGWTGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSE 98 +N +SL++ D + + +E +RQ +ELIASEN SRA L+A GS L NKY+E Sbjct: 3 SNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYAE 62 Query: 99 GYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPH 158 GYPGKRYYGG E DE+E L R F+ A NVQP+SG+ AN AV AL +P Sbjct: 63 GYPGKRYYGGCEFADEVEALAIERVKRLFNAGHA----NVQPHSGAQANGAVMLALAKPG 118 Query: 159 DRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRP 218 D ++G+ L GGHLTHG + + + +F ++ Y ++ T LIDY+Q+ A+ +P Sbjct: 119 DTVLGMSLDAGGHLTHG-----AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHKP 173 Query: 219 RLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTT 278 LIIAG SAY R +D+AR R + D V A L+ DMAHI+G++AA +P +HA +VT+TT Sbjct: 174 SLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTSTT 233 Query: 279 HKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVA 338 HKTLRG R G + +IN AVFP LQGGP H IA AVA Sbjct: 234 HKTLRGPRGGFVLTND--------------EEIAKKINSAVFPGLQGGPLMHVIAGKAVA 279 Query: 339 LKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAER 398 +A T F+ Y +VL NA+A+ D L G LV+GGTDNHL+LVDLRPKGL GA+ E+ Sbjct: 280 FGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVEQ 339 Query: 399 VLELVSITANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 LE IT NKN P D G+RLG PA T+R F +FR V I Sbjct: 340 ALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLI--------- 390 Query: 458 VKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 L+ F++ +R+ + FP+ Sbjct: 391 -------LEVFEALRTNPEGDHATEQRVRREIFALCERFPI 424 >4WXB-A nrPDB Length = 428 Score = 561 bits (1446), Expect = e-160, Method: Composition-based stats. Identities = 194/457 (42%), Positives = 270/457 (59%), Gaps = 46/457 (10%) Query: 44 TGQESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGK 103 +E DPE+W + E +RQ +ELIASEN S+A + A G+ L NKY+EGYPGK Sbjct: 15 FDKEDYKAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGK 74 Query: 104 RYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMG 163 RYYGG V+D +E L RA + F A NVQP+SGS AN AVY +L+QP D +MG Sbjct: 75 RYYGGTAVIDVVETLAIERAKKLFGAKFA----NVQPHSGSQANAAVYMSLIQPGDTVMG 130 Query: 164 LDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIA 223 +DL GGHLTHG +S + + + Y ++ ++ L+DY+ + A+ RP+LI+A Sbjct: 131 MDLSAGGHLTHG-----APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVA 185 Query: 224 GTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLR 283 G SAY+R+ID+A+ RE+ D V A+L+ DMAHI+GLVA+ PSP +A + TTTTHKTLR Sbjct: 186 GASAYSRIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLR 245 Query: 284 GARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQAC 343 G R GLI ++N AVFP LQGGP H IAA AVALK+A Sbjct: 246 GPRGGLILTDD--------------EDIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEAL 291 Query: 344 TPMFREYSLQVLKNARAMADALLER-GYSLVSGGTDNHLVLVDLRPKGLDGARAERVLEL 402 P F+EY V+KNA AMAD + + ++SGGT+NHL LVD+ +G A+ VLE Sbjct: 292 DPAFKEYGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEE 351 Query: 403 VSITANKNTCPGDR-SAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSK 461 V+IT NKN+ P ++ S G+R+G+PA+TSR E + R++ +++ E Sbjct: 352 VNITLNKNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEA---------- 401 Query: 462 TAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 L++ + + L +R V+ AFP+ Sbjct: 402 -----------LENHDKPEVLERIRGDVKVLTDAFPL 427 >5VC2-A nrPDB Length = 424 Score = 558 bits (1439), Expect = e-159, Method: Composition-based stats. Identities = 181/451 (40%), Positives = 251/451 (55%), Gaps = 46/451 (10%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 L +D E++EL+ E RQ LE+IASEN+ + +EA+GS L NKY+EGYP KRYYGG Sbjct: 13 LEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKRYYGG 72 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 EVVD+IE L RA + F+ A NVQ +SGS AN AVY ALL+P+D+I+G+DL Sbjct: 73 CEVVDKIESLAIERAKKLFNCQFA----NVQAHSGSQANNAVYHALLKPYDKILGMDLSC 128 Query: 169 GGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAY 228 GGHLTHG ++S T ++S Y +N G IDY + A+ +P +I+ G SAY Sbjct: 129 GGHLTHG-----AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCGFSAY 182 Query: 229 ARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSG 288 R ID+ + RE+ DEV A LL D+AH++GLV PF H +V++TTHKTLRG R G Sbjct: 183 PREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRGPRGG 242 Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFR 348 +I +I+ A+FP QGGP H IAA AV K+ P F+ Sbjct: 243 IILTND--------------EEIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLKPEFK 288 Query: 349 EYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSITAN 408 Y+ V N + +A AL E+ + LVSGGT NHL+L+D K G A+ L IT N Sbjct: 289 AYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAGITVN 348 Query: 409 KNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKTAKLQD 467 KNT PG+ RS G+R+G+ AL++R +F + + I + Sbjct: 349 KNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISD----------------- 391 Query: 468 FKSFLLKDSETSQRLANLRQRVEQFARAFPM 498 +L D ++++ ++ A FP+ Sbjct: 392 ----ILNDINNVSLQLHVKEELKAMANQFPV 418 >3H7F-A nrPDB Length = 447 Score = 552 bits (1422), Expect = e-157, Method: Composition-based stats. Identities = 210/463 (45%), Positives = 272/463 (58%), Gaps = 53/463 (11%) Query: 48 SLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYG 107 L++ DP++ ELL +E RQ LE+IASENF RA L+A GS L NKY+EG PG+RYYG Sbjct: 25 PLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRRYYG 84 Query: 108 GAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLP 167 G E VD +E L + RA F + A NVQP+SG+ AN AV AL+ P +R++GLDL Sbjct: 85 GCEHVDVVENLARDRAKALFGAEFA----NVQPHSGAQANAAVLHALMSPGERLLGLDLA 140 Query: 168 DGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 +GGHLTHG R++ + +E+ Y ++P T LID + + TA FRP++IIAG SA Sbjct: 141 NGGHLTHGM-----RLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAGWSA 195 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARS 287 Y R++D+A R + DEV A LL DMAH +GLVAA + PSP HAD+V+TT HKTL G RS Sbjct: 196 YPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGGGRS 255 Query: 288 GLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF 347 GLI ++ + IN AVFP QGGP H IA AVALK A TP F Sbjct: 256 GLIVGKQ---------------QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAATPEF 300 Query: 348 REYSLQVLKNARAMADALL-----ERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLEL 402 + + L AR +AD L+ + G S+VSGGTD HLVLVDLR LDG AE +L Sbjct: 301 ADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDLLHE 360 Query: 403 VSITANKNTCPGD-RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSK 461 V IT N+N P D R + GLR+G PAL +R F + +F V D I + G Sbjct: 361 VGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATG------ 414 Query: 462 TAKLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPM-PGFDE 503 +S ++ L+ R + ARAFP+ G +E Sbjct: 415 ----------------SSVDVSALKDRATRLARAFPLYDGLEE 441 >4BHD-A nrPDB Length = 428 Score = 439 bits (1130), Expect = e-123, Method: Composition-based stats. Identities = 133/434 (30%), Positives = 214/434 (49%), Gaps = 41/434 (9%) Query: 49 LSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGG 108 SD + ++ ++ + ++LIASEN S A EA + ++Y+EG PGKR Y G Sbjct: 2 YSDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQG 61 Query: 109 AEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPD 168 + +DE+E LC + E F + A NVQP SG ANLAV+ A +P D++M L +PD Sbjct: 62 CKYIDEVETLCIELSKELFKAEHA----NVQPTSGVVANLAVFFAETKPGDKLMALSVPD 117 Query: 169 GGHLTHGYMSDVKRISATSI-FFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSA 227 GGH++H ++SA I + + + +P+ ID + + +P+LI+ G S Sbjct: 118 GGHISHW------KVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSL 171 Query: 228 YARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKH-ADIVTTTTHKTLRGAR 286 + A E EV A + D AH+ GL+A K P + A+ + +THKT G + Sbjct: 172 FPFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQ 231 Query: 287 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 346 G+I K D+I+ VFP + H H A +A+AL + Sbjct: 232 GGVILTTK---------------ENADKIDSHVFPGVVSNHHLHHKAGLAIALAEML--E 274 Query: 347 FRE-YSLQVLKNARAMADALLERGYSLV---SGGTDNHLVLVDLRPKG---LDGARAERV 399 F E Y+ QV+KNA+A+A AL ERG++++ T++H V++D+ + ++ Sbjct: 275 FGEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKM 334 Query: 400 LELVSITANKNTCPGD--RSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLE 457 E +I NKN P D ++ P G+RLG T +E + + +F+ I ++ Sbjct: 335 YEEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKR---IAID 391 Query: 458 VKSKTAKLQDFKSF 471 + +D K F Sbjct: 392 KEKPEKVREDVKEF 405 >3TQX-A nrPDB Length = 399 Score = 52.4 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 61/313 (19%), Positives = 113/313 (36%), Gaps = 46/313 (14%) Query: 146 ANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLID 205 AN ++ LL P D I+ L H + D R+ ++ Y+ D Sbjct: 115 ANGGLFETLLGPEDAIIS------DELNHASIIDGIRLC------KAQRYRYKNNAMG-D 161 Query: 206 YNQLALTARLFRPRL-IIAGTSAYARLIDYARMREVCD---EVKAHLLADMAHISGLVAA 261 A R +IA ++ A ++ +CD + A ++ D +H G + Sbjct: 162 LEAKLKEADEKGARFKLIATDGVFSMDGIIADLKSICDLADKYNALVMVDDSHAVGFIGE 221 Query: 262 KVIPSPFKHA------DIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRI 315 +P ++ DI+T T K L GA G + + ++ R PY F + Sbjct: 222 NGRGTP-EYCGVADRVDILTGTLGKALGGASGG--YTSGHKEIIEWLRNRSRPYLFSN-- 276 Query: 316 NFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSG 375 V P I A ++ + + + Q+ +N+R + + G+ LV G Sbjct: 277 --TVAP---------VIVATSLKVLELLKTEGPQLRKQLQENSRYFRAGMEKLGFQLVPG 325 Query: 376 GTDNHLVL-VDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSR 434 NH ++ V L L A+ +L+ I + P + +R+ A+ ++ Sbjct: 326 ---NHPIIPVMLGDAQLATNMADHLLQE-GIYVVGFSYP--VVPMGKARIRVQMSAVHTQ 379 Query: 435 QFREDDFRRVVDF 447 Q + Sbjct: 380 QQLDRAIEAFGQV 392 >1M6S-A nrPDB Length = 347 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 64/323 (19%), Positives = 113/323 (34%), Gaps = 56/323 (17%) Query: 102 GKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRI 161 G YG ++E+E L A E F + A + SG+ N A Q D + Sbjct: 30 GDDVYGEDPTINELERL----AAETFGKEAALFVP-----SGTMGNQVSIMAHTQRGDEV 80 Query: 162 MGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTAR---LFRP 218 + L H+ + A ++ MP+ + K G +D + + R + P Sbjct: 81 I---LEADSHI------FWYEVGAMAVLSGVMPHPVPGKNGAMDPDDVRKAIRPRNIHFP 131 Query: 219 RL-IIAGTSAYAR----LIDYARMREVC---DEVKAHLLADMAHI-SGLVAAKVIPSPFK 269 R +IA + + R ++ ++E+C E ++ D A I + +A+ V P K Sbjct: 132 RTSLIAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGV---PVK 188 Query: 270 ----HADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQG 325 +AD V K L ++ + K + + Q Sbjct: 189 EYAGYADSVMFCLSKGLCAPVGSVVVGDRDFIERARKARKMLGGGMR-----------QA 237 Query: 326 GPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVD 385 G +AA + +E NAR +A L E GYS+ ++V++ Sbjct: 238 G----VLAAAGIIALTKMVDRLKEDHE----NARFLALKLKEIGYSVNPEDVKTNMVILR 289 Query: 386 LRPKGLDGARAERVLELVSITAN 408 ++ L + AN Sbjct: 290 TDNLKVNAHGFIEALRNSGVLAN 312 >3WY7-A nrPDB Length = 404 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 43/179 (24%), Positives = 62/179 (34%), Gaps = 27/179 (15%) Query: 142 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 201 SG ANL AL P L L+H + D R+S + P++ Sbjct: 125 SGYTANLGALVALSGPG------SLIVSDALSHASLVDACRLSRARVV--VSPHRDVDAV 176 Query: 202 GLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMRE---VCDEVKAHLLADMAHISGL 258 + A ++ S ++ D A +R+ VC A LL D AH GL Sbjct: 177 DAALAARTEERA-------VVVTESVFSADGDLAPLRDLHAVCRRHGALLLVDEAH--GL 227 Query: 259 VAAKVIPSPFKH-------ADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYT 310 H DIV TTT G++ G + + V+A T R + Sbjct: 228 GVRGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVLGPEAVRAHLIDTARSFIFD 286 >2X8U-A nrPDB Length = 412 Score = 40.8 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 67/346 (19%), Positives = 111/346 (32%), Gaps = 53/346 (15%) Query: 87 ALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPA 146 A G +++ G G R G + C+ E + + A +G A Sbjct: 65 AAGKQALDEFGSGTTGSRVLNGTYQGHKA---CEDALKEFYGTEHAIVFS-----TGYQA 116 Query: 147 NLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDY 206 NL + + L D I+ LD + G I F + L+ + G + Sbjct: 117 NLGMISTLAGKGDYII-LDADSHASIYDGCWLGDAEIV---RFRHNSVEDLDKRLGRLPA 172 Query: 207 NQLALTARLFRPRLIIAGTSAYARLIDYARMRE---VCDEVKAHLLADMAHISGLVAA-- 261 L Y+ + D A ++E V + A +L D AH G Sbjct: 173 EAGKLVVLE----------GVYSMMGDIAPLQEMVAVSKKHGAMILVDEAHGMGFFGEHG 222 Query: 262 -KVIPSPFKHADI--VTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFA 318 V AD+ V T K++ G G V R +T Sbjct: 223 RGVFEEAGVEADVDFVVGTFSKSV-GTVGGFCVSNHPKFEVLRLVCRPYVFTASLP---- 277 Query: 319 VFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTD 378 PS +A A ++++ + + KN+R + L + GY L + Sbjct: 278 --PS--------VVATAATSIRKLMHA--GDKRAHLWKNSRRLHQGLRDMGYKLGTETAQ 325 Query: 379 NHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGL 424 + ++ V L A + +LE + N R TP G+ Sbjct: 326 SAIIAVILTDMAQAVALWQGLLE-AGLYVN-----TARPPATPAGM 365 >3A2B-A nrPDB Length = 398 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 64/340 (18%), Positives = 118/340 (34%), Gaps = 55/340 (16%) Query: 95 KYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTAL 154 KY G G R+ G +D L L A+ A + +G +NL + L Sbjct: 72 KYGTGCAGSRFLNGT--LDIHVEL--EEKLSAYVGKEAAILFS----TGFQSNLGPLSCL 123 Query: 155 LQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTAR 214 + +D I+ LD D H + D R+S + + + Y N D Sbjct: 124 MGRNDYIL-LDERD-----HASIIDGSRLSFS----KVIKYGHNNME---DLRAKLSRLP 170 Query: 215 LFRPRLIIAG--TSAYARLIDYARMREVCDEVKAHLLADMAHISGLV-----AAKVIPSP 267 +LI S +++ + + +E A ++ D AH G++ Sbjct: 171 EDSAKLICTDGIFSMEGDIVNLPELTSIANEFDAAVMVDDAHSLGVIGHKGAGTASHFGL 230 Query: 268 FKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGP 327 D++ T K+L + G + V R + ++ ++ P Sbjct: 231 NDDVDLIMGTFSKSL-ASLGGFVAGDADVIDFLKHNARSVMFS------ASMTP------ 277 Query: 328 HNHAIAAVAVALK--QACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVD 385 A+VA LK + E+ ++ KN LL+ G+ L G T++ ++ + Sbjct: 278 -----ASVASTLKALEIIQNE-PEHIEKLWKNTDYAKAQLLDHGFDL--GATESPILPIF 329 Query: 386 LRPKGLDGARAERVLELVSITAN---KNTCPGDRSAITPG 422 +R ++L+ + N P + S I Sbjct: 330 IRSNEKT-FWVTKMLQDDGVFVNPVVSPAVPAEESLIRFS 368 >1CS1-A nrPDB Length = 386 Score = 40.1 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 64/170 (37%), Gaps = 29/170 (17%) Query: 120 QRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSD 179 +RAL + V +G A V T L+P D ++ GG Sbjct: 57 VQRAL----AELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGG--------- 103 Query: 180 VKRISATSIFFESMPYKLNPKTGLIDY--NQLALTARLFRPRLIIAGTSAYA--RLIDYA 235 + F+S+ + + +D Q A +P+L++ + + R++D A Sbjct: 104 ------SYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIA 157 Query: 236 RMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKH-ADIVTTTTHKTLRG 284 ++ + EV A + D +S + +P AD+V + K L G Sbjct: 158 KICHLAREVGAVSVVDNTFLS-----PALQNPLALGADLVLHSCTKYLNG 202 >1FC4-A nrPDB Length = 401 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 42/215 (19%), Positives = 74/215 (34%), Gaps = 31/215 (14%) Query: 205 DYNQLALTARLFRPR----LIIAGTSAYARLIDYARMR---EVCDEVKAHLLADMAHISG 257 D +L + R ++IA ++ A ++ ++ D+ A ++ D +H G Sbjct: 160 DMQELEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVG 219 Query: 258 LVAAK-----VIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFE 312 V DI+T T K L GA G RK V + R Sbjct: 220 FVGENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSR------- 272 Query: 313 DRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372 P L AI A ++ + + E ++ NAR + + G++L Sbjct: 273 --------PYLFSNSLAPAIVAASIKVLEMVEAG-SELRDRLWANARQFREQMSAAGFTL 323 Query: 373 VSGGTDNHLVLVDLRPKGLDGARAERVLELVSITA 407 G D H ++ + + + R L+ I Sbjct: 324 --AGAD-HAIIPVMLGDAVVAQKFARELQKEGIYV 355 >2AEV-A nrPDB Length = 374 Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 23/107 (21%), Positives = 45/107 (42%), Gaps = 8/107 (7%) Query: 220 LIIAGTSAYARLIDYARMREV---CDEVKAHLLADMAHISGLVAAKVIPSPFKH---ADI 273 +II G++ ++I+ ++V +A + D A SG + P AD+ Sbjct: 144 VIITGSTMDLKVIELENFKKVINTAKNKEAIVFVDDA--SGARVRLLFNQPPALKLGADL 201 Query: 274 VTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVF 320 V T+T K + G R GL+ +K + G + + + ++ Sbjct: 202 VVTSTDKLMEGPRGGLLAGKKELVDKIYIEGTKFGLEAQPPLLAGIY 248 >3OP7-A nrPDB Length = 375 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 26/121 (21%), Positives = 55/121 (45%), Gaps = 19/121 (15%) Query: 138 VQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKL 197 +Q + ANL V +L++P D ++ L + T+ + D+ + S+ E +++ Sbjct: 85 LQTNGATGANLLVLYSLIEPGDHVISL------YPTYQQLYDIPK----SLGAEVDLWQI 134 Query: 198 NPKTGLIDYNQLALTARLFRP--RLIIAGTSAYAR--LID---YARMREVCDEVKAHLLA 250 + G + L +L RP ++I + ++D + E+ EV A++L+ Sbjct: 135 EEENGWL--PDLEKLRQLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEVGAYILS 192 Query: 251 D 251 D Sbjct: 193 D 193 >2OKK-A nrPDB Length = 497 Score = 37.4 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 43/232 (18%), Positives = 78/232 (33%), Gaps = 35/232 (15%) Query: 174 HGYMSDVKRISATSIFFESM-PYKLNPKTGLIDYNQLALTARLFRPRLII-------AGT 225 H + S K +A I +S+ K + + +I + L + + + AGT Sbjct: 193 HSHFSLKKGAAALGIGTDSVILIKCDERGKMIPSD-LERRILEAKQKGFVPFLVSATAGT 251 Query: 226 SAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIP---SPFKHADIVTTTTHKTL 282 + Y + ++C + K + D A GL+ ++ S + A+ VT HK + Sbjct: 252 TVYGAFDPLLAVADICKKYKIWMHVDAAWGGGLLMSRKHKWKLSGVERANSVTWNPHKMM 311 Query: 283 RGAR--SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPS---LQGGPHNHAIA---- 333 S L+ +G+ + + + + + LQ G H Sbjct: 312 GVPLQCSALLVREEGLMQNCNQMHASYLFQQDKHYDLSYDTGDKALQCGRHVDVFKLWLM 371 Query: 334 --AVAVALKQACTP---MFREYSLQVLKNARAMADALLERGYSLVSGGTDNH 380 A +A EY ++KN GY +V G H Sbjct: 372 WRAKGTTGFEAHVDKCLELAEYLYNIIKN---------REGYEMVFDGKPQH 414 >2BWN-A nrPDB Length = 401 Score = 36.6 bits (83), Expect = 0.028, Method: Composition-based stats. Identities = 49/218 (22%), Positives = 77/218 (35%), Gaps = 31/218 (14%) Query: 218 PRLIIAGTSAYARLIDYARMREVCD---EVKAHLLADMAHISGLV----AAKVIPSPFKH 270 P+LI A S Y+ D+ ++E+CD E A D H G+ A H Sbjct: 179 PKLI-AFESVYSMDGDFGPIKEICDIAEEFGALTYIDEVHAVGMYGPRGAGVAERDGLMH 237 Query: 271 -ADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHN 329 DI T K G G I + VD + F + A+ Q Sbjct: 238 RIDIFNGTLAKAY-GVFGGYI--AASARMVDAVRSYAPGFIFSTSLPPAIAAGAQA---- 290 Query: 330 HAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPK 389 +IA + A Q + Q+ +A+ + L G ++ G+ H+V V + Sbjct: 291 -SIAFLKTAEGQKLRD-----AQQM--HAKVLKMRLKALGMPIIDHGS--HIVPVVIGDP 340 Query: 390 GLDGARAERVLELVSITA---NKNTCP--GDRSAITPG 422 A ++ +L + N T P +R TP Sbjct: 341 VHTKAVSDMLLSDYGVYVQPINFPTVPRGTERLRFTPS 378 >3NNK-A nrPDB Length = 411 Score = 35.0 bits (79), Expect = 0.074, Method: Composition-based stats. Identities = 42/212 (19%), Positives = 74/212 (34%), Gaps = 36/212 (16%) Query: 82 RAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPY 141 L A+ S L +Y P +Y E++ R F + +W + V Sbjct: 26 PRVLRAMSSQLIGQYD---PAMTHYMN-------EVMALYRG--VFRTEN-RWTMLVDGT 72 Query: 142 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 201 S + A+ + ++P D+++ +P G H +R A E P Sbjct: 73 SRAGIE-AILVSAIRPGDKVL---VPVFGRFGHLLCEIARRCRAEVHTIEV------PWG 122 Query: 202 GLIDYNQLALTARLFRPRLI--IAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLV 259 + +Q+ + RPRL+ + G ++ L A + E+C A D Sbjct: 123 EVFTPDQVEDAVKRIRPRLLLTVQGDTSTTMLQPLAELGEICRRYDALFYTD-------A 175 Query: 260 AAKVIPSPFKH----ADIVTTTTHKTLRGARS 287 A + +P + D V+ K L G Sbjct: 176 TASLGGNPLETDVWGLDAVSAGMQKCLGGPSG 207 >3BB8-A nrPDB Length = 437 Score = 33.9 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 49/255 (19%), Positives = 89/255 (34%), Gaps = 39/255 (15%) Query: 60 LQREKDRQCRGLELIA--SENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEIEL 117 + +E+ RQ EL+A +E + EA S + P + G E+ +E Sbjct: 1 MSQEELRQQIA-ELVAQYAETAMAPKPFEAGKSVVP-------PSGKVIGTKELQLMVEA 52 Query: 118 -----LCQRRALEAFD---LDPAQWGVNVQPYSGSPANLAVYTAL---------LQPHDR 160 L R +AF+ + + SGS ANL TAL L+P D Sbjct: 53 SLDGWLTTGRFNDAFEKKLGEYLGVPYVLTTTSGSSANLLALTALTSPKLGVRALKPGDE 112 Query: 161 IMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRL 220 ++ + G+ + V + + ++ T ++ + + A + + Sbjct: 113 VIT--------VAAGFPTTVNPTIQNGLI--PVFVDVDIPTYNVNASLIEA-AVSDKTKA 161 Query: 221 IIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHK 280 I+ + L D A +R V D+ L+ D G + F V+ K Sbjct: 162 IMIAHTL-GNLFDLAEVRRVADKYNLWLIEDCCDALGSTYDGKMAGTFGDIGTVSFYPAK 220 Query: 281 TLRGARSGLIFYRKG 295 + G +F + Sbjct: 221 HITMGEGGAVFTQSA 235 >5XT5-A nrPDB Length = 419 Score = 33.5 bits (75), Expect = 0.25, Method: Composition-based stats. Identities = 36/239 (15%), Positives = 76/239 (31%), Gaps = 38/239 (15%) Query: 81 SRAALEALGSCLNNKYSEGYPGKRYYG----GAEVVDEIELLCQRRALEAFDLD------ 130 RA +E L +KY Y + G G D E + + + + Sbjct: 37 PRAVIETL-----DKYYNQYNSNVHRGVHTLGTRATDGYEG-AREKVRKFINAKSMAEII 90 Query: 131 ---PAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATS 187 +N+ S + AN L+P D ++ + ++ + + AT Sbjct: 91 FTKGTTTSLNMVALSYARAN-------LKPGDEVVITYMEHHANIIPWQQA----VKATG 139 Query: 188 IFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLI-DYARMREVCDEVKA 246 + +P + + G I + T + ++ S + M ++ + A Sbjct: 140 ATLKYIPLQ---EDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGA 196 Query: 247 HLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGR 305 ++ D A + + V D ++HK + G + Y K + + Sbjct: 197 VIVVDGAQSTPHMKIDVQD---LDCDFFALSSHK-MCGPTGVGVLYGKKALLENMEPAE 251 >6NPB-A nrPDB Length = 383 Score = 33.1 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 16/76 (21%), Positives = 30/76 (39%), Gaps = 3/76 (3%) Query: 131 PAQWGVN--VQPYSGSPANLAVYTALLQ-PHDRIMGLDLPDGGHLTHGYMSDVKRISATS 187 A W + + P + SP N + P D + L D G LT + + K ++ Sbjct: 33 HAIWLRDNALDPETRSPGNGQRLITIGDIPADTRISTALVDDGALTVTFAPEGKTVTFPG 92 Query: 188 IFFESMPYKLNPKTGL 203 + +S Y + + + Sbjct: 93 KWLKSNAYDTDQSSEV 108 >6ONN-A nrPDB Length = 402 Score = 32.3 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 30/122 (24%), Positives = 46/122 (37%), Gaps = 20/122 (16%) Query: 142 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 201 +G ANLA TAL + L H + D R+S I + P+ Sbjct: 119 TGYMANLATLTALAGRGTTLFSDS------LNHASLIDGARLSRADI--QIYPHA----- 165 Query: 202 GLIDYNQLALT--ARLFRPRLIIAG--TSAYARLIDYARMREVCDEVKAHLLADMAHISG 257 D L A +LI++ S + AR+ E+ + A L+ D AH G Sbjct: 166 ---DAEALGAMLEASDAAVKLIVSDTVFSMDGDIAPLARLLELAEHHGAWLVVDDAHGFG 222 Query: 258 LV 259 ++ Sbjct: 223 VL 224 >1GC4-A nrPDB Length = 385 Score = 31.6 bits (70), Expect = 0.76, Method: Composition-based stats. Identities = 50/248 (20%), Positives = 85/248 (34%), Gaps = 55/248 (22%) Query: 41 RGWTGQESLSDSDPEMW-ELLQREKDRQCRGLELIA---------SENFCSRAALEALGS 90 RG + + D + E RQ G++L+A + AA AL Sbjct: 2 RGLSRRVQAMKPDAVVAVNAKALELRRQ--GVDLVALTAGEPDFDTPEHVKEAARRALAQ 59 Query: 91 CLNNKYS--EGYPGKRYYGGAEVVDEIELLCQR-RALEAFDLDPAQWGVNVQPYSGSPAN 147 KY+ G P R E L ++ R + P + V V GS A Sbjct: 60 GKT-KYAPPAGIPELR-----------EALAEKFRRENGLSVTPEETIVTV---GGSQAL 104 Query: 148 LAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYN 207 ++ A+L P D ++ L+ ++S + + + + P+ G + Sbjct: 105 FNLFQAILDPGDEVIV--------LSPYWVSYPEMVRFAGGV--VVEVETLPEEGFVPDP 154 Query: 208 QLALTARLFRPRLIIAG------TSAYARLIDYA--------RMREVCDEVKAHLLADMA 253 + A R + ++ + Y + + A V DE+ HLL + Sbjct: 155 ERVRRAITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGE 214 Query: 254 HIS-GLVA 260 H S G VA Sbjct: 215 HFSPGRVA 222 >2OKJ-A nrPDB Length = 504 Score = 31.6 bits (70), Expect = 0.78, Method: Composition-based stats. Identities = 18/103 (17%), Positives = 38/103 (36%), Gaps = 11/103 (10%) Query: 191 ESMPYKLNPKTGLIDYNQLALTARLFRPRLII-------AGTSAYARLIDYARMREVCDE 243 + K N + +I + + + + AGT+ Y + ++C++ Sbjct: 215 NVILIKCNERGKIIPAD-FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEK 273 Query: 244 VKAHLLADMAHISGLVAAKVIP---SPFKHADIVTTTTHKTLR 283 L D A GL+ ++ + + A+ VT HK + Sbjct: 274 YNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMG 316 >2OGE-A nrPDB Length = 399 Score = 31.6 bits (70), Expect = 0.84, Method: Composition-based stats. Identities = 32/139 (23%), Positives = 52/139 (37%), Gaps = 18/139 (12%) Query: 124 LEAFDLDPAQWGVN---VQPYSGSPANLAVYTAL-LQPHDRIMGLDLPDGGHLTHGYMSD 179 LE F+ + A + V SG A L + P D ++ +P +H Y++ Sbjct: 65 LEGFEAEFAAYCETDHAVGVNSGMDALQLALRGLGIGPGDEVI---VP-----SHTYIAS 116 Query: 180 VKRISATSIFFESMPYKLNPKTGLIDYNQL-ALTARLFRPRLIIAGTSAYARLIDYARMR 238 +SAT + P + P + L A R R ++ Y D +R Sbjct: 117 WLAVSATG----ATPVPVEPHEDHPTLDPLLVEKAITPRTRALLP-VHLYGHPADMDALR 171 Query: 239 EVCDEVKAHLLADMAHISG 257 E+ D H++ D A G Sbjct: 172 ELADRHGLHIVEDAAQAHG 190 >5HH9-A nrPDB Length = 390 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 43/258 (16%), Positives = 80/258 (31%), Gaps = 32/258 (12%) Query: 138 VQP----YSGSPAN--LAVYTALL-QPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFF 190 VQP +GS + A+Y LL QP I+ + T+ + + T Sbjct: 74 VQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEH--YSTYTTLEYRHKRMGT---- 127 Query: 191 ESMPYKLNPKTGLIDYNQLAL-TARLFRPRLIIAGT----SAYARLIDYARMREVCDEVK 245 + + L + +++ A RP+ + G S + + ++ E+ Sbjct: 128 QVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELN 187 Query: 246 AH--------LLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVK 297 + D H G V + F D THK L G R + + + Sbjct: 188 QKRDEQDRIIYVVDGVH--GFGVEDVSFADFD-CDYFIAGTHKWLFGPRGTGVIIARSEQ 244 Query: 298 AVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKN 357 + ++ D + P G A+ A + E ++ + Sbjct: 245 LQEHLVPSIPTFSRADNFGTLMTPG--GYHAFEHRLALGTAFELHLQLGKAEVQARIHQL 302 Query: 358 ARAMADALLER-GYSLVS 374 + L E LV+ Sbjct: 303 NAYLKQRLGEHPKVRLVT 320 >1XI9-A nrPDB Length = 406 Score = 31.2 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 17/61 (27%), Positives = 26/61 (42%), Gaps = 1/61 (1%) Query: 102 GKRYYGGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRI 161 G YYG +E + E+ R +D V V + + A ++ ALL P D I Sbjct: 70 GHNYYGDSEGLPELRKAIVEREKRKNGVDITPDDVRVTA-AVTEALQLIFGALLDPGDEI 128 Query: 162 M 162 + Sbjct: 129 L 129 >3TRI-A nrPDB Length = 280 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 27/159 (16%), Positives = 56/159 (35%), Gaps = 13/159 (8%) Query: 339 LKQACTPMFREYSLQVLKNARAMADALLERGYSLVSGG-----TDNHLVLVDLRPKGLDG 393 K+ C + + Q NA + A+ +V ++ ++++ L G+ Sbjct: 45 FKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISL-AVGVTT 103 Query: 394 ARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVN 453 E+ L S P TP +R GA L + + + D + + + I V Sbjct: 104 PLIEKWLGKASRIVR--AMPN-----TPSSVRAGATGLFANETVDKDQKNLAESIMRAVG 156 Query: 454 IGLEVKSKTAKLQDFKSFLLKDSETSQRLANLRQRVEQF 492 + + V S+ + + + L++ EQ Sbjct: 157 LVIWVSSEDQIEKIAALSGSGPAYIFLIMEALQEAAEQL 195 >3Q8X-B nrPDB Length = 287 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 40/101 (39%), Gaps = 17/101 (16%) Query: 289 LIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMF- 347 LI +K V++ P + + + A+F QG + I KQ P F Sbjct: 23 LIQGKKAVESPTAFLLGGQPGSGKTSLRSAIFEETQG----NVIVIDNDTFKQQH-PNFD 77 Query: 348 ---REYSLQVLKN--------ARAMADALLERGYSLVSGGT 377 + Y V+K+ A+ L ++GY+LV GT Sbjct: 78 ELVKLYEKDVVKHVTPYSNRMTEAIISRLSDQGYNLVIEGT 118 >5JAY-A nrPDB Length = 402 Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 55/302 (18%), Positives = 98/302 (32%), Gaps = 53/302 (17%) Query: 142 SGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKT 201 +G ANLA TAL + L H + D R+S + Y Sbjct: 119 TGYMANLATLTALAGRGTTLFS------DALNHASLIDGARLSRA----DVQIYP----- 163 Query: 202 GLIDYNQLALT--ARLFRPRLIIAGTSAYARLIDYA---RMREVCDEVKAHLLADMAHIS 256 D + L+ A ++I++ + ++ D A R+ E+ ++ A L+ D AH Sbjct: 164 -HCDTDALSAMLEASDADVKVIVSD-TVFSMDGDIAPLPRLLELAEQHGAWLIVDDAHGF 221 Query: 257 GLVA----AKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFE 312 G++ + + + ++++ T G + + V + R +T Sbjct: 222 GVLGPQGRGAIAQAALRSPNLISIGTLDKAAGVSGAFVAAHETVIEWLVQRARPYIFTTA 281 Query: 313 DRINFAVFPSLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSL 372 A HA++A + R + Q++ RAM A Sbjct: 282 SVPAAA-----------HAVSASLRIIGGEEGDARRAHLQQLIGRTRAMLKATPWLPV-- 328 Query: 373 VSGGTDNHLVLVDLRPKGLDGA-RAERVLELVSITANKNTCPGDRSAITPGG---LRLGA 428 D+H + L D L+ + P R P G LR+ Sbjct: 329 -----DSHTAVQPLIIGANDATLEIAATLDRAGL-----WVPAIRPPTVPTGTSRLRISL 378 Query: 429 PA 430 A Sbjct: 379 SA 380 >5O5C-A nrPDB Length = 519 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 30/166 (18%), Positives = 59/166 (35%), Gaps = 27/166 (16%) Query: 143 GSPANLAVYT-------ALLQPHDRIMGLDLPDGG--------HLTHGYMSDVKRISATS 187 G+ +NL A P I LP L+H S K ++ Sbjct: 170 GTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSH--FSIQKSMAILG 227 Query: 188 IFFESMPYKLNPKTGLIDYNQLAL-----TARLFRPRLIIA--GTSAYARLIDYARMREV 240 + ++++ + +D + L + P ++A GT+ + + + E+ Sbjct: 228 LGYDAVIPVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDPLGAISEL 287 Query: 241 CDEVKAHLLADMAHISGLVAAKVIP---SPFKHADIVTTTTHKTLR 283 C + D A+ GL+ ++ + + AD VT HK+ Sbjct: 288 CKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHKSFF 333 >3WPR-A nrPDB Length = 229 Score = 30.4 bits (67), Expect = 2.1, Method: Composition-based stats. Identities = 24/160 (15%), Positives = 52/160 (32%), Gaps = 18/160 (11%) Query: 322 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLV------SG 375 GP + + A T + A + + + G ++V + Sbjct: 57 GTITGPTYNVAQGNQTNVGDALTA-----LDNAINTAATTSKSTVSNGQNIVVSKSKNAD 111 Query: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ 435 G+DN+ V + VL IT N + + +T G P++T Sbjct: 112 GSDNYEVSTAKDLTVDSVKAGDTVLNNAGITIGNNAVVLNNTGLTIS----GGPSVTLAG 167 Query: 436 F--REDDFRRVVDFIDEGVNIGL-EVKSKTAKLQDFKSFL 472 + V + ++ + ++K K+++ S + Sbjct: 168 IDAGNKTIQNVANAVNATDAVNKGQMKQIEDKIEEILSKI 207 >5TXT-B nrPDB Length = 491 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 16/60 (26%), Positives = 27/60 (45%), Gaps = 7/60 (11%) Query: 205 DYNQLALTARLFR---PRLIIAGTSAYA---RLIDYARMREVCDEVKAHLLADMAHISGL 258 D N+L + + P+LI A S Y+ + D ++ ++ D+ A D H GL Sbjct: 173 DLNELEQLLQSYPKSVPKLI-AFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGL 231 >5W70-A nrPDB Length = 445 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 15/98 (15%), Positives = 29/98 (29%), Gaps = 2/98 (2%) Query: 197 LNPKTGLIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHIS 256 ++P T + + +++ Y+ L D + + + L+ D A Sbjct: 142 VDPDTLCLSPEAVEAAITEHTRAIVVV--HLYSALADMDALSAIAERHGLPLIEDCAQAH 199 Query: 257 GLVAAKVIPSPFKHADIVTTTTHKTLRGARSGLIFYRK 294 G V A + K L G + R Sbjct: 200 GATYRGVKVGALATAGTFSMQHSKVLTSGEGGAVITRD 237 >3W1J-A nrPDB Length = 392 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 25/53 (47%), Gaps = 4/53 (7%) Query: 272 DIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQ 324 D+V+ + K L G ++G+I +K + + ++ P RI+ L+ Sbjct: 217 DLVSGSGDKLLGGPQAGIIVGKKNLI----EKIKKNPIARALRIDKLTLSGLE 265 >3W1H-A nrPDB Length = 452 Score = 30.0 bits (66), Expect = 2.5, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 25/53 (47%), Gaps = 4/53 (7%) Query: 272 DIVTTTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQ 324 D+V+ + K L G ++G+I +K + + ++ P RI+ L+ Sbjct: 277 DLVSGSGDKLLGGPQAGIIVGKKNLI----EKIKKNPIARALRIDKLTLSGLE 325 >3WPA-A nrPDB Length = 427 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 21/136 (15%), Positives = 42/136 (30%), Gaps = 17/136 (12%) Query: 322 SLQGGPHNHAIAAVAVALKQACTPMFREYSLQVLKNARAMADALLERGYSLV------SG 375 GP + + A T + A + + + G ++V + Sbjct: 57 GTITGPTYNVAQGNQTNVGDALTA-----LDNAINTAATTSKSTVSNGQNIVVSKSKNAD 111 Query: 376 GTDNHLVLVDLRPKGLDGARAERVLELVSITANKNTCPGDRSAITPGGLRLGAPALTSRQ 435 G+DN+ V + VL IT N + + +T G P++T Sbjct: 112 GSDNYEVSTAKDLTVDSVKAGDTVLNNAGITIGNNAVVLNNTGLTIS----GGPSVTLAG 167 Query: 436 F--REDDFRRVVDFID 449 + V + ++ Sbjct: 168 IDAGNKTIQNVANAVN 183 >5JWG-A nrPDB Length = 703 Score = 29.6 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 27/64 (42%), Gaps = 13/64 (20%) Query: 55 EMWELLQREKDR--QCRGLELIASENFCSRAALEALGSCLNNKYSEGYPGKRY-----YG 107 ++ +++E +R + GLE F S L +L + K + PG RY YG Sbjct: 110 DVTAAVKKELERIKKPSGLE------FLSPRYLSSLAPEIVGKKAASRPGYRYEIKAFYG 163 Query: 108 GAEV 111 G Sbjct: 164 GNRY 167 >1RVG-A nrPDB Length = 305 Score = 29.6 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 25/69 (36%), Gaps = 14/69 (20%) Query: 203 LIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAK 262 ID+ +L ARL L++ G SA + R R E+ AA Sbjct: 188 FIDHARLERIARLVPAPLVLHGASAVPPEL-VERFRASGGEIGE-------------AAG 233 Query: 263 VIPSPFKHA 271 + P K A Sbjct: 234 IHPEDIKKA 242 >2YWH-A nrPDB Length = 600 Score = 29.3 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 16/26 (61%) Query: 140 PYSGSPANLAVYTALLQPHDRIMGLD 165 PY G+ A + ++ ++P D+IM + Sbjct: 204 PYRGAVAFVRIFDGEVKPGDKIMLMS 229 >3WGB-A nrPDB Length = 341 Score = 29.3 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 41/202 (20%), Positives = 70/202 (34%), Gaps = 18/202 (8%) Query: 123 ALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDLPDGGHLTHGYMSDVKR 182 ALEA+ D + SG+ +NL + Q + G L H+ + Y + Sbjct: 43 ALEAYGADLLGKEAALFVPSGTMSNLLAVMSHCQRGE---GAVLGSAAHI-YRYEAQGSA 98 Query: 183 ISATSIFFESMPYKLNPKTGLIDY-NQLALTARLFRPRLIIAGTSAYAR---LIDYAR-M 237 + S+ + +P + + L D +A F P ++ + + + Y R M Sbjct: 99 V-LGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVCLENTHNGKVLPLPYLREM 157 Query: 238 REVCDEVKAHLLADMAHISGLVAAKVIP-----SPFKHADIVTTTTHKTLRGARSGLIFY 292 RE+ DE L D A + V A +PF D V+ K L L+ Sbjct: 158 RELVDEHGLQLHLDGARLFNAVVASGHTVRELVAPF---DSVSICLSKGLGAPVGSLLVG 214 Query: 293 RKGVKAVDPKTGREIPYTFEDR 314 A + + + Sbjct: 215 SHAFIARARRLRKMVGGGMRQA 236 >2D1S-A nrPDB Length = 548 Score = 29.3 bits (64), Expect = 4.6, Method: Composition-based stats. Identities = 11/45 (24%), Positives = 21/45 (46%), Gaps = 7/45 (15%) Query: 71 LELIASENFCSRAALEALGSCLNNKYSEGYPGKRYYGGAEVVDEI 115 + L + +N + ++ + S ++N KR GG VDE+ Sbjct: 487 VVLESGKNMTEKEVMDYVASQVSN-------AKRLRGGVRFVDEV 524 >2FJK-A nrPDB Length = 305 Score = 28.9 bits (63), Expect = 5.8, Method: Composition-based stats. Identities = 17/69 (24%), Positives = 27/69 (39%), Gaps = 14/69 (20%) Query: 203 LIDYNQLALTARLFRPRLIIAGTSAYARLIDYARMREVCDEVKAHLLADMAHISGLVAAK 262 ID+ +LA A+L L++ G SA + + R R E+ A+ Sbjct: 188 FIDHPRLARIAKLVPAPLVLHGASAVPQEL-VERFRAAGGEIGE-------------ASG 233 Query: 263 VIPSPFKHA 271 + P K A Sbjct: 234 IHPEDIKKA 242 >1XNG-A nrPDB Length = 268 Score = 28.9 bits (63), Expect = 6.2, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 64/172 (37%), Gaps = 20/172 (11%) Query: 348 REYSLQVLKNARAMADALLERGYSLV----SGGTDNHLVLVDLRPKGLDGARAERVLELV 403 ++Y ++ + + +RG+ V SGG D+ +V V + + A A + V Sbjct: 3 KDYQKLIVYLCDFLEKEVQKRGFKKVVYGLSGGLDSAVVGVLCQKVFKENAHALLMPSSV 62 Query: 404 SITANKN---------TCPGDRSAITPGGLRLGA----PALTSRQ--FREDDFRRVVDFI 448 S+ NK + P +I P + +LT + + D+ Sbjct: 63 SMPENKTDALNLCEKFSIPYTEYSIAPYDAIFSSHFKDASLTRKGNFCARLRMAFLYDYS 122 Query: 449 DEGVNIGLEVKSKTAKLQDFKSFLLKDSETSQRLANL-RQRVEQFARAFPMP 499 + ++ + +K+ ++ + + + + L + V + AR +P Sbjct: 123 LKSDSLVIGTSNKSERMLGYGTLFGDLACAINPIGELFKTEVYELARRLNIP 174 >6C9E-A nrPDB Length = 422 Score = 28.1 bits (61), Expect = 8.9, Method: Composition-based stats. Identities = 42/265 (15%), Positives = 77/265 (29%), Gaps = 32/265 (12%) Query: 157 PHDRIMGLDLPDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLF 216 P + I+ + ++ M K + P LN G + + Sbjct: 128 PDEEILITHMEHHSNIVPWQMVCKK----MGCKLQVAPISLN---GEVILEEFERKLNEN 180 Query: 217 RPRLIIAGTSAYARLI-DYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVT 275 + I S I M ++ EV A +L D A + + V D Sbjct: 181 TKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQD---LDCDFYA 237 Query: 276 TTTHKTLRGARSGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAV 335 + HK + G + + K + IN F + + H A Sbjct: 238 FSGHK-MYGPTGIGVLWGKEELLNSMTP----YQGGGEMINSVSFEATEYAAIPHKFEAG 292 Query: 336 AVALKQACT-------------PMFREYSLQVLKNARAMADALLERGYSLVSGGTDNHLV 382 + A EY Q+L A +A+ +GY+++ G N + Sbjct: 293 TPNIAGAIGLAAAIDYIWSLDLDAIAEYETQLLNYATKAIEAV--KGYNII-GTAANKVP 349 Query: 383 LVDLRPKGLDGARAERVLELVSITA 407 ++ + +L+ I Sbjct: 350 IISFVHGKIHAHDIGTILDSEGIAI 374 >3ZX6-A nrPDB Length = 341 Score = 28.1 bits (61), Expect = 9.3, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 31/75 (41%), Gaps = 8/75 (10%) Query: 11 RPLQRCGQLVRMAIRAQHSNAAQTQTGE---ANRGWTGQESLSDSDPEMWELL-----QR 62 R L R VR A +S A++ TG ++R SL ++ M +L Sbjct: 48 RSLMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNA 107 Query: 63 EKDRQCRGLELIASE 77 E RQ L L ASE Sbjct: 108 ENARQASHLALSASE 122 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.134 0.379 Lambda K H 0.267 0.0412 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,120,305 Number of Sequences: 36641 Number of extensions: 838754 Number of successful extensions: 2434 Number of sequences better than 10.0: 65 Number of HSP's better than 10.0 without gapping: 51 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 2206 Number of HSP's gapped (non-prelim): 102 length of query: 504 length of database: 10,336,785 effective HSP length: 101 effective length of query: 403 effective length of database: 6,636,044 effective search space: 2674325732 effective search space used: 2674325732 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 61 (28.1 bits)