BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P34896 (483 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1BJ4-A nrPDB 971 0.0 1RVY-A nrPDB 900 0.0 1EJI-A nrPDB 883 0.0 5X3V-A nrPDB 637 0.0 6CCZ-A nrPDB 557 e-159 5Z0Y-A nrPDB 549 e-156 5XMU-A nrPDB 418 e-117 4O6Z-A nrPDB 399 e-111 2DKJ-A nrPDB 370 e-103 3ECD-A nrPDB 361 e-100 1YJS-A nrPDB 360 1e-99 4J5U-A nrPDB 359 2e-99 3PGY-A nrPDB 355 2e-98 3N0L-A nrPDB 355 2e-98 3G8M-A nrPDB 343 1e-94 5VMB-A nrPDB 341 5e-94 3H7F-A nrPDB 336 1e-92 3GBX-A nrPDB 336 2e-92 4WXB-A nrPDB 334 5e-92 4P3M-A nrPDB 332 3e-91 5VC2-A nrPDB 330 1e-90 4OTL-A nrPDB 327 5e-90 4BHD-A nrPDB 202 3e-52 5HSI-A nrPDB 30 1.6 3H9N-A nrPDB 29 4.5 3VKQ-A nrPDB 29 5.1 3T2C-A nrPDB 28 6.8 2RAG-A nrPDB 28 8.1 >1BJ4-A nrPDB Length = 470 Score = 971 bits (2509), Expect = 0.0, Method: Compositional matrix adjust. Identities = 467/470 (99%), Positives = 467/470 (99%) Query: 11 DADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 70 DADLWSSHD MLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN Sbjct: 1 DADLWSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 60 Query: 71 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 130 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA Sbjct: 61 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 120 Query: 131 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 190 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA Sbjct: 121 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 180 Query: 191 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 250 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV Sbjct: 181 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 240 Query: 251 VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIA 310 VTTTTHKTLRGCRAGMIFYRKGVKSVDP TGKEILYNLESLINSAVFPGLQGGPHNHAIA Sbjct: 241 VTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIA 300 Query: 311 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 370 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG Sbjct: 301 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 360 Query: 371 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE Sbjct: 361 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 420 Query: 431 LTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 480 LTLQIQSDTGV ATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL Sbjct: 421 LTLQIQSDTGVAATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 470 >1RVY-A nrPDB Length = 483 Score = 900 bits (2327), Expect = 0.0, Method: Compositional matrix adjust. Identities = 445/480 (92%), Positives = 462/480 (96%), Gaps = 1/480 (0%) Query: 5 VNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEA 64 VNGA +DA LWSSH++MLAQPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEA Sbjct: 4 VNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEA 63 Query: 65 LGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPAN 124 LGSCLNNKYS+GYPGQRYYGGTE IDELETLCQKRALQAY LDPQCWGVNVQPYSGSPAN Sbjct: 64 LGSCLNNKYSQGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPAN 123 Query: 125 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYD 184 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESM YKVNPDTGYI+YD Sbjct: 124 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYD 183 Query: 185 QLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSP 244 +LEENARLFHPKLIIAGTSCYSRNL+Y RLRKIADENGAYLMADMAHISGLV AGVVPSP Sbjct: 184 RLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSP 243 Query: 245 FEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGP 304 FEHCHVVTTTTHKTLRGCRAGMIFYR+GV+SVDPKTGKEILYNLESLINSAVFPGLQGGP Sbjct: 244 FEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGP 303 Query: 305 HNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR 364 HNHAIAGVAVALKQAMT EFK YQ QVVANCRALS AL ELGYKIVTGGSDNHLILVDLR Sbjct: 304 HNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLR 363 Query: 365 SKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 424 SKGTDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLEKDFQKVAHF Sbjct: 364 SKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 423 Query: 425 IHRGIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483 IHRGIELT+QIQ DTG RATLKEFKE+LAGD K+Q AV+ALR+EVESFA+LFPLPGLP F Sbjct: 424 IHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGLPGF 483 >1EJI-A nrPDB Length = 478 Score = 883 bits (2281), Expect = 0.0, Method: Compositional matrix adjust. Identities = 435/477 (91%), Positives = 454/477 (95%), Gaps = 1/477 (0%) Query: 8 AHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGS 67 A +DA LW+SH+KML+QPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEALGS Sbjct: 2 ADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGS 61 Query: 68 CLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAV 127 LNNKYSEGYPGQRYYGGTEFIDELE LCQKRALQAY LDPQCWGVNVQPYSGSPANFAV Sbjct: 62 SLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAV 121 Query: 128 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLE 187 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKV P+TGYINYDQLE Sbjct: 122 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLE 181 Query: 188 ENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEH 247 ENA LFHPKLIIAGTSCYSRNL+YARLRKIAD+NGAYLMADMAHISGLVAAGVVPSPFEH Sbjct: 182 ENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEH 241 Query: 248 CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNH 307 CHVVTTTTHKTLRGCRAGMIFYRKGV+SVDPKTGKE Y LESLINSAVFPGLQGGPHNH Sbjct: 242 CHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNH 301 Query: 308 AIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKG 367 AIAGVAVALKQAMT EFK+YQ QV+ANCRALS+ALTELGYKIVTGGSDNHLIL+DLRSKG Sbjct: 302 AIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKG 361 Query: 368 TDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHR 427 TDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLE+DFQKVAHFIHR Sbjct: 362 TDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHR 421 Query: 428 GIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483 GIELTLQIQS +ATLKEFKE+LAGD K Q+AV LREEVE+FAS F LPGLPDF Sbjct: 422 GIELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPDF 478 >5X3V-A nrPDB Length = 496 Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust. Identities = 303/458 (66%), Positives = 365/458 (79%), Gaps = 4/458 (0%) Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 + L DSD E++ ++++E +RQ GLELIASENF SRA LEALGSCLNN+YSEGYPG+RYY Sbjct: 26 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNRYSEGYPGKRYY 85 Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 GG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++PH RIMGLDL Sbjct: 86 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 145 Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203 PDGGHLTHG+M+D K+ISATSIFFESMPYK+NP TG I+Y+QL ARLF P+LIIAGTS Sbjct: 146 PDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTS 205 Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263 Y+R ++YAR+R++ DE A+L+ADMAHISGLVAA V+PSPF+H +VTTTTHKTLRG R Sbjct: 206 AYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGAR 265 Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323 +G+IFYRKGVK+VDPKTG+EI Y E IN AVFP LQGGPHNHAIA VAVALKQA T Sbjct: 266 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 325 Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383 F+ Y QV+ N RA+++AL E GY +V+GG+DNHL+LVDLR KG DG RAE+VLE SI Sbjct: 326 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 385 Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKNTCPGDRSA+ P GLRLG PALTSR E DF++V FI G+ + L+++S T A Sbjct: 386 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT---A 442 Query: 444 TLKEFKERLAGDKYQAAVQA-LREEVESFASLFPLPGL 480 L++FK L D + A LR+ VE FA FP+PG Sbjct: 443 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 480 >6CCZ-A nrPDB Length = 455 Score = 557 bits (1435), Expect = e-159, Method: Compositional matrix adjust. Identities = 276/461 (59%), Positives = 344/461 (74%), Gaps = 20/461 (4%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 L ++D +V+ II KE +RQ LELIASENF S+AV+EA+GSCL NKYSEG PG+RYYGG Sbjct: 9 LSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGG 68 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E IDELE LCQ+RAL A+ LD WGVNVQP SGSPANFAVYTA+++PH RIMGLDLP Sbjct: 69 NEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPH 128 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHL+HGFMT K+++S TSI+FESMPY+++ TG I+YD LE+ A LF PKLIIAG S Y Sbjct: 129 GGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAY 188 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 R+++YAR RKIAD GA+LM DMAH+SGL+AA V+ PFE +VTTTTHK+LRG R G Sbjct: 189 PRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGG 248 Query: 266 MIFYRK-GVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324 MIF++K V VD LES IN+AVFPGLQGGPHNH I G+AV LK A + +F Sbjct: 249 MIFFKKDAVHGVD----------LESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDF 298 Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384 K YQ+QVVANCRAL+ L E YK+V+GGSDNHL+LVDLR G DG R EK+L+ SI Sbjct: 299 KNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITL 358 Query: 385 NKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQ---SDTGV 441 NKN+ PGD+SAL P G+R+G+PA+T+RGL EK+F+ +A IH G+ ++L+ + S T V Sbjct: 359 NKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKV 418 Query: 442 RATLKEF--KERLAGDKYQAAVQALREEVESFASLFPLPGL 480 + L E GDK V LR +VE+ A+ +P+PG+ Sbjct: 419 QDFLNFVLAPEFPLGDK----VSNLRRKVEALATQYPIPGV 455 >5Z0Y-A nrPDB Length = 470 Score = 549 bits (1414), Expect = e-156, Method: Compositional matrix adjust. Identities = 260/465 (55%), Positives = 346/465 (74%), Gaps = 3/465 (0%) Query: 14 LWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKY 73 L H +M+ L ++D EV IIK E +RQ+ + LIASENF S +V +ALG+ + NKY Sbjct: 6 LSPEHKQMVEGHLAETDPEVNQIIKDEVDRQKHSIVLIASENFTSTSVFDALGTPMCNKY 65 Query: 74 SEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVE 133 SEGYPG RYYGG E ID +E LCQ+RAL+A+ LD WGVNVQ SGSPAN VY A+++ Sbjct: 66 SEGYPGARYYGGNEHIDRMEILCQQRALKAFHLDGSRWGVNVQTLSGSPANLQVYQAIMK 125 Query: 134 PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLF 193 PH R+MGLDLP GGHL+HG+ TD +KISA S +FE+MPY+V+ +TG I+YD LE+ A L+ Sbjct: 126 PHDRLMGLDLPHGGHLSHGYQTDTRKISAVSTYFETMPYRVDLETGIIDYDMLEKTAVLY 185 Query: 194 HPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTT 253 PK+++AGTS Y R ++Y R+R+IAD+ GAYL+ DMAHISGL+AAGV+PSPFE+ +VTT Sbjct: 186 RPKVLVAGTSAYCRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTT 245 Query: 254 TTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVA 313 TTHK+LRG R MIF+RKGV+SV+PKTGKEI Y+LE+ IN +VFPG QGGPHNH IA +A Sbjct: 246 TTHKSLRGPRGAMIFFRKGVRSVNPKTGKEIYYDLENPINFSVFPGHQGGPHNHTIAALA 305 Query: 314 VALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRA 373 ALKQA T EFK YQ QV+ N +AL LGYK+V+ G+D+H++LV L+ K DG R Sbjct: 306 TALKQAATPEFKQYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGARI 365 Query: 374 EKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTL 433 E V E +IA NKN+ PGDRSAL P G+R+G PA+T+RG E+DF K+A++I + ++ Sbjct: 366 ETVCENINIALNKNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYAK 425 Query: 434 QIQSDTGVRAT-LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477 ++QS+ + A LK+FK ++A + + L+ E+ ++A FPL Sbjct: 426 KVQSELPIEANKLKDFKAKIAEGSDE--ITQLKNEISAWAGEFPL 468 >5XMU-A nrPDB Length = 442 Score = 418 bits (1075), Expect = e-117, Method: Compositional matrix adjust. Identities = 215/455 (47%), Positives = 295/455 (64%), Gaps = 17/455 (3%) Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 +PL+ D E+++I+ E RQR + LIASEN + AV E LG+ ++NKYSEGYP +RYY Sbjct: 5 EPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSNKYSEGYPKKRYY 64 Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 GG +FID++E LCQKRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L Sbjct: 65 GGNDFIDKIEELCQKRALEAFNVSDEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHL 124 Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203 GGHLTHGF +KKK+S TS FES YK N GY++ D + E A F PK+II G + Sbjct: 125 CSGGHLTHGFFDEKKKVSITSDMFESKLYKCN-SQGYVDLDAVREMALSFKPKVIICGYT 183 Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263 Y R+++Y + R+I DE AYL AD++HIS VA ++ +PF H VVTTTTHK LRG R Sbjct: 184 SYPRDIDYQQFRQICDEVNAYLFADISHISSFVACNILNNPFLHADVVTTTTHKILRGPR 243 Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323 + +IF+ K +P +E INSAVFP QGGPHN+ IA VA LK+ + Sbjct: 244 SALIFFN---KKRNP--------GIEQKINSAVFPSFQGGPHNNKIAAVACQLKEVHSPA 292 Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383 FK Y QV+ N +AL++AL +VT G+DNHLI+VDLR G + ++ A +++ Sbjct: 293 FKEYTQQVLLNSKALAKALISKQIDLVTNGTDNHLIVVDLRKFSITGSKLQETCNAINVS 352 Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKNT P D + PSG+R+GTPA+T+RG EKD + +A + R I++T+ +Q G + Sbjct: 353 LNKNTIPSDVDCVSPSGVRIGTPAMTTRGAKEKDMEFIADVLARAIKITVDLQEQYGKK- 411 Query: 444 TLKEFKERLAGDKYQAAVQALREEVESFASLFPLP 478 L +FK+ L G+ A +Q L++EV ++A P P Sbjct: 412 -LVDFKKGLPGN---AQLQQLKQEVVTWAGALPFP 442 >4O6Z-A nrPDB Length = 480 Score = 399 bits (1026), Expect = e-111, Method: Compositional matrix adjust. Identities = 208/453 (45%), Positives = 288/453 (63%), Gaps = 17/453 (3%) Query: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84 PL+ D E++++++KE NRQ + LIASEN + AV E LG ++NKYSEGYP +RYYG Sbjct: 44 PLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRYYG 103 Query: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144 G +++D++E LC KRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L Sbjct: 104 GNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHLC 163 Query: 145 DGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSC 204 GGHLTHGF +KKK+S TS FES YK N + GY++ + + A F PK+II G + Sbjct: 164 SGGHLTHGFFDEKKKVSITSDLFESKLYKCNSE-GYVDMESVRNLALSFQPKVIICGYTS 222 Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 264 Y R+++Y R+I DE AYL AD++HIS VA ++ +PF + VVTTTTHK LRG R+ Sbjct: 223 YPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKILRGPRS 282 Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324 +IF+ K +P ++ INS+VFP QGGPHN+ IA VA LK+ T EF Sbjct: 283 ALIFFN---KKRNP--------GIDQKINSSVFPSFQGGPHNNKIAAVACQLKEVNTPEF 331 Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384 K Y QV+ N +AL+E L + +VT G+DNHLI+VDLR G + ++ A +IA Sbjct: 332 KEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCNAINIAL 391 Query: 385 NKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 NKNT P D + PSG+R+GTPALT+RG EKD + +A + + I LT ++Q G + Sbjct: 392 NKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQKYGKK-- 449 Query: 445 LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477 L +FK+ L + + L++EV +A P Sbjct: 450 LVDFKKGLVNN---PKIDELKKEVVQWAKNLPF 479 >2DKJ-A nrPDB Length = 407 Score = 370 bits (950), Expect = e-103, Method: Compositional matrix adjust. Identities = 206/450 (45%), Positives = 265/450 (58%), Gaps = 51/450 (11%) Query: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89 D ++ +I E RQR GLELIASENF S+ V EA+GS L NKY+EGYPG RYYGG E I Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEVI 67 Query: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149 D +E+L +RA + W NVQP+SGS AN AVY AL+EP +MG+DL GGHL Sbjct: 68 DRVESLAIERAKALFG---AAWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123 Query: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209 THG +++ + ++ + Y V PDT I+ +++ A PK+I+AG S Y R Sbjct: 124 THG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFW 178 Query: 210 EYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFY 269 ++ R+IADE GAYL+ DMAH +GLVAAG+ P+P + HVVT+TTHKTLRG R G+I Sbjct: 179 DFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL- 237 Query: 270 RKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQH 329 S DP+ GK I+ +FPG+QGGP H IAG AVA +A+ EFK Y Sbjct: 238 -----SNDPELGKR--------IDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSR 284 Query: 330 QVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTC 389 VV N + L+E L GY+IVTGG+DNHL LVDLR KG G AE+ L+A I NKN Sbjct: 285 LVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAI 344 Query: 390 PGDRSALR-PSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEF 448 P D R SG+R+GTPA+T+RG ++ VA I R + Sbjct: 345 PFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRAL------------------- 385 Query: 449 KERLAGDKYQAAVQALREEVESFASLFPLP 478 + +ALREEV A P+P Sbjct: 386 --------LEGPSEALREEVRRLALAHPMP 407 >3ECD-A nrPDB Length = 425 Score = 361 bits (927), Expect = e-100, Method: Compositional matrix adjust. Identities = 200/412 (48%), Positives = 256/412 (62%), Gaps = 24/412 (5%) Query: 15 WSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 74 S+ + +Q L + D V I KE RQ+ +ELIASEN SRAVL+A GS L NKY+ Sbjct: 2 MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYA 61 Query: 75 EGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEP 134 EGYPG+RYYGG EF DE+E L +R + + NVQP+SG+ AN AV AL +P Sbjct: 62 EGYPGKRYYGGCEFADEVEALAIERVKRLF----NAGHANVQPHSGAQANGAVMLALAKP 117 Query: 135 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFH 194 ++G+ L GGHLTHG K + + +F ++ Y V+ DT I+YDQ+E A+ Sbjct: 118 GDTVLGMSLDAGGHLTHG-----AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHK 172 Query: 195 PKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 254 P LIIAG S Y R L++AR R IAD GA LM DMAHI+G++AAG +P EH HVVT+T Sbjct: 173 PSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTST 232 Query: 255 THKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 314 THKTLRG R G + + D + K+ INSAVFPGLQGGP H IAG AV Sbjct: 233 THKTLRGPRGGFVL------TNDEEIAKK--------INSAVFPGLQGGPLMHVIAGKAV 278 Query: 315 ALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374 A +A+T +FK Y +V+AN +AL + L G +VTGG+DNHL+LVDLR KG G + E Sbjct: 279 AFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVE 338 Query: 375 KVLEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425 + LE I CNKN P D SG+RLGTPA T+RG +F++V I Sbjct: 339 QALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLI 390 >1YJS-A nrPDB Length = 419 Score = 360 bits (923), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 193/429 (44%), Positives = 269/429 (62%), Gaps = 32/429 (7%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 L D +V+ I++E RQ +ELIASENF SRAV+EA GS L NKY+EGYPG+RYYGG Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D +E L ++RA Q + + NVQP+SG+ AN AVY ++E ++G++L Sbjct: 64 CEYVDIVEELARERAKQLFGAE----HANVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + + + + Y V+P+T I+YD + E ARL PKLI+A S Y Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAAASAY 174 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 R +++A+ R+IADE GAYLM DMAHI+GLVAAG+ P+P + H VTTTTH+TLRG R G Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGG 234 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 MI ++ I+ A+FPG+QGGP H IA AVA +A+ +FK Sbjct: 235 MILCQE---------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDDFK 279 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 Y +VV N + L+ AL G+ +V+GG+DNHL+LVDLR + G AEKVL+ I N Sbjct: 280 AYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVN 339 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KNT P D S SG+R+GT A+T+RG ++ ++A I G+ L + G Sbjct: 340 KNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIAAII--GLVL-----KNVGSEQA 392 Query: 445 LKEFKERLA 453 L+E ++R+A Sbjct: 393 LEEARQRVA 401 >4J5U-A nrPDB Length = 420 Score = 359 bits (921), Expect = 2e-99, Method: Compositional matrix adjust. Identities = 194/401 (48%), Positives = 253/401 (63%), Gaps = 24/401 (5%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 L ++D E+ IIK E RQ +ELIASENF S AVLEA G+ L NKY+EGYP +R+Y G Sbjct: 8 LHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRFYNG 67 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E +D+ E L +R + + C NVQP+SGS AN AVY AL++P ++G+ L Sbjct: 68 CEEVDKAENLAIERVKKLF----NCKYANVQPHSGSQANQAVYLALLQPGDTVLGMSLDS 123 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG + + +F ++ Y VN +T I+YD++E A L PKL+IAG S Y Sbjct: 124 GGHLTHGAAPN-----MSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGFSAY 178 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 RN+++A+ R+I D+ GAY MAD+AHI+GLVA G SP + H VT+TTHKTLRG R G Sbjct: 179 PRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGPRGG 238 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I S D + G + INSA+FPGLQGGP H IA AVA + + E+K Sbjct: 239 LIL------SNDEEIGHK--------INSALFPGLQGGPLMHIIAAKAVAFLENLQPEYK 284 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 Y QV++N +AL+ +L E GY I+TGG+DNH++LVDLR G G A L+ I CN Sbjct: 285 SYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGITCN 344 Query: 386 KNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425 KN P D S SG+RLGTPA T+RG EKDF V H + Sbjct: 345 KNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMV 385 >3PGY-A nrPDB Length = 415 Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 196/430 (45%), Positives = 263/430 (61%), Gaps = 33/430 (7%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + D + I++E RQ +ELIASENF S AV+EA GS L NKY+EGYPG+RYYGG Sbjct: 7 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 66 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 EF+D E++ RA + + VNVQP+SG AN AVY +E ++G++L Sbjct: 67 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGPQANMAVYLVALEMGDTVLGMNLSH 122 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + F+ + Y V+ DT INYD++ + A PKLI+AG S Y Sbjct: 123 GGHLTHG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAY 177 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 SR +++ + ++IADE A LM DMAHI+GLVAAG+ P+P E+ VTTTTHKTLRG R G Sbjct: 178 SRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 237 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 MI ++ K I+ +FPG+QGGP H IA AVA +A+ FK Sbjct: 238 MILCKEEYKKD---------------IDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFK 282 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR-SKGTDGGRAEKVLEACSIAC 384 YQ QVV N + L+EAL G++IV+GG+DNHL+ VD++ S G G AE+ L++ I C Sbjct: 283 TYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITC 342 Query: 385 NKNTCPGDRSA-LRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKNT P D+ SG+RLGTPA T+RG EK F++VA I L L+ D Sbjct: 343 NKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKI----ISLALKNSKD---EE 395 Query: 444 TLKEFKERLA 453 L++ KER+A Sbjct: 396 KLQQAKERVA 405 >3N0L-A nrPDB Length = 417 Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust. Identities = 192/404 (47%), Positives = 259/404 (64%), Gaps = 25/404 (6%) Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82 A L+ D E++++ KE RQ GLE+IASENF V+E +GS L NKY+EGYPG+RY Sbjct: 3 AMSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRY 62 Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142 YGG EF+DE+ETL +R + + C NVQP SGS AN VY AL+ P +I+G+D Sbjct: 63 YGGCEFVDEIETLAIERCKKLF----NCKFANVQPNSGSQANQGVYAALINPGDKILGMD 118 Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202 L GGHLTHG K+S++ +ES Y V D G I+Y+++ E A+ PKLI+ G Sbjct: 119 LSHGGHLTHG-----AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGA 172 Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262 S Y+R +++A+ R+IADE GAYL AD+AHI+GLV AG PSPF + HVV++TTHKTLRG Sbjct: 173 SAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGP 232 Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322 R G+I + D + K+ INSA+FPG+QGGP H IA AV K ++ Sbjct: 233 RGGIIM------TNDEELAKK--------INSAIFPGIQGGPLMHVIAAKAVGFKFNLSD 278 Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382 E+KVY QV N + L+ L + +K+V+ G+DNHL+L+ + G A+ L I Sbjct: 279 EWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGI 338 Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425 NKNT PG+ RS SGLRLGTPALT+RG EK+ + V+++I Sbjct: 339 TANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYI 382 >3G8M-A nrPDB Length = 417 Score = 343 bits (879), Expect = 1e-94, Method: Compositional matrix adjust. Identities = 195/401 (48%), Positives = 261/401 (65%), Gaps = 23/401 (5%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + D D E++ +++E RQ +ELIASEN+ S V++A GS L NK++EGYPG+RYYGG Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKFAEGYPGKRYYGG 67 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D +E L RA + + D NVQP+SGS ANFAVYTAL+EP ++G++L Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + + +PY ++ TG+I+Y LE+ A+ PK+II G S Y Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSAY 177 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 S +++A++R+IAD GAYL DMAH++GLVAAGV P+P H HVVTTTTHKTL G R G Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I K G E LY +NSAVFPG QGGP H IAG AVALK+AM EFK Sbjct: 238 LIL---------AKGGSEELY---KKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFK 285 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 YQ QV N +A+ E E GYK+V+GG+DNHL LVDL K G A+ L +I N Sbjct: 286 TYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVN 345 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425 KN+ P D +S SG+R+GTPA+T RG E + +++A ++ Sbjct: 346 KNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386 >5VMB-A nrPDB Length = 425 Score = 341 bits (874), Expect = 5e-94, Method: Compositional matrix adjust. Identities = 186/401 (46%), Positives = 254/401 (63%), Gaps = 23/401 (5%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + + D E+ I E RQ +ELIASEN+ S AV+EA GS L NKY+EGYPG+RYYGG Sbjct: 15 ISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGG 74 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 EF+D +E + RA + + D NVQP++GS AN AVY AL+ P ++G+ L Sbjct: 75 CEFVDVIEQMAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLNPGDTVLGMSLAH 130 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG K+S + + ++ Y +N +TG I+Y+++E A P++I+AG S Y Sbjct: 131 GGHLTHG-----AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSAY 185 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 SR +++ R R IAD+ GAYL DMAH++GLVAAGV P+P + V TTTTHKTLRG R+G Sbjct: 186 SRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRSG 245 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I K +EI E + SAVFPG QGGP HAIA A+ K+AM+ +FK Sbjct: 246 LIL---------AKANEEI----EKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDFK 292 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 YQ QVV N +A++E GY +V+GG+DNHL L+ L + G A+ L A I N Sbjct: 293 AYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITVN 352 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425 KN+ P D RS SG+R+GTPA+T+RG E + +++A +I Sbjct: 353 KNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWI 393 >3H7F-A nrPDB Length = 447 Score = 336 bits (862), Expect = 1e-92, Method: Compositional matrix adjust. Identities = 198/438 (45%), Positives = 259/438 (59%), Gaps = 35/438 (7%) Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81 ++ PL + D ++ ++ KE RQR LE+IASENF RAVL+A GS L NKY+EG PG+R Sbjct: 22 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 81 Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141 YYGG E +D +E L + RA + + NVQP+SG+ AN AV AL+ P R++GL Sbjct: 82 YYGGCEHVDVVENLARDRAKALFGAE----FANVQPHSGAQANAAVLHALMSPGERLLGL 137 Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201 DL +GGHLTHG +++ + +E+ Y V+P T I+ D + A F PK+IIAG Sbjct: 138 DLANGGHLTHGM-----RLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAG 192 Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261 S Y R L++A R IADE GA L+ DMAH +GLVAAG+ PSP H VV+TT HKTL G Sbjct: 193 WSAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG 252 Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321 R+G+I GK+ INSAVFPG QGGP H IAG AVALK A T Sbjct: 253 GRSGLI------------VGKQ---QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAAT 297 Query: 322 LEFKVYQHQVVANCRALSEAL-----TELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKV 376 EF Q + ++ R +++ L + G +V+GG+D HL+LVDLR DG AE + Sbjct: 298 PEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDL 357 Query: 377 LEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 435 L I N+N P D R + SGLR+GTPAL +RG + +F +VA I L Sbjct: 358 LHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADI----IATALAT 413 Query: 436 QSDTGVRATLKEFKERLA 453 S V A LK+ RLA Sbjct: 414 GSSVDVSA-LKDRATRLA 430 >3GBX-A nrPDB Length = 420 Score = 336 bits (861), Expect = 2e-92, Method: Compositional matrix adjust. Identities = 188/401 (46%), Positives = 261/401 (65%), Gaps = 23/401 (5%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + D D E++ +++E RQ +ELIASEN+ S V++A GS L NKY+EGYPG+RYYGG Sbjct: 11 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 70 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D +E L RA + + D NVQP+SGS ANFAVYTAL++P ++G++L Sbjct: 71 CEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 126 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + + +PY ++ ++G I+YD++ + A+ PK+II G S Y Sbjct: 127 GGHLTHG-----SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSAY 180 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 S +++A++R+IAD GAYL DMAH++GL+AAGV P+P H HVVTTTTHKTL G R G Sbjct: 181 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 240 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I K G E LY +NSAVFP QGGP H IAG AVALK+AM EFK Sbjct: 241 LIL---------AKGGDEELY---KKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFK 288 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 VYQ QV N +A+ E GYK+V+GG++NHL L+DL K G A+ L +I N Sbjct: 289 VYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVN 348 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425 KN+ P D +S SG+R+G+PA+T RG E + +++A ++ Sbjct: 349 KNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 389 >4WXB-A nrPDB Length = 428 Score = 334 bits (856), Expect = 5e-92, Method: Compositional matrix adjust. Identities = 182/406 (44%), Positives = 260/406 (64%), Gaps = 25/406 (6%) Query: 27 KDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGT 86 K D E++N I E+ RQ+ +ELIASEN S+AV+ A G+ L NKY+EGYPG+RYYGGT Sbjct: 21 KAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRYYGGT 80 Query: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146 ID +ETL +RA + + NVQP+SGS AN AVY +L++P +MG+DL G Sbjct: 81 AVIDVVETLAIERAKKLFG----AKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAG 136 Query: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206 GHLTHG +S + + + Y V+ ++ ++YD + A+ PKLI+AG S YS Sbjct: 137 GHLTHG-----APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYS 191 Query: 207 RNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGM 266 R +++A+ R+IAD GAYLM DMAHI+GLVA+G PSP + HV TTTTHKTLRG R G+ Sbjct: 192 RIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGL 251 Query: 267 IFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKV 326 I T E ++ +NSAVFPGLQGGP H IA AVALK+A+ FK Sbjct: 252 IL-----------TDDE---DIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKE 297 Query: 327 YQHQVVANCRALSEALTE-LGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 Y V+ N A+++ + +++++GG++NHL LVD+ +G A+ VLE +I N Sbjct: 298 YGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLN 357 Query: 386 KNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430 KN+ P ++ S + SG+R+G+PA+TSRG+ E + +++A ++ +E Sbjct: 358 KNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALE 403 >4P3M-A nrPDB Length = 429 Score = 332 bits (850), Expect = 3e-91, Method: Compositional matrix adjust. Identities = 187/429 (43%), Positives = 254/429 (59%), Gaps = 26/429 (6%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + D D E++ I E RQ +ELIASEN+ S V+EA GS L NKY+EGYPG+RYYGG Sbjct: 8 IADYDPELWQSITDEVQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D E+L +RA + D NVQP+SGS AN AVY AL P I+G+ L Sbjct: 68 CEYVDVAESLAIERAKSLFGADY----ANVQPHSGSQANAAVYQALCAPGDTILGMSLAH 123 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG +S + + ++ Y + P+TG ++Y ++E A P +IIAG S Y Sbjct: 124 GGHLTHG-----SHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSAY 178 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 S +++A+ R+IAD+ GAYL DMAH++GLVAAG+ P+P VVTTTTHKTL G R G Sbjct: 179 SGIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKTLGGPRGG 238 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I + +E +NSAVFPG QGGP H IA AVA K+ EF Sbjct: 239 LILAKANEA-------------IEKKLNSAVFPGQQGGPLMHVIAAKAVAFKECAEPEFA 285 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 VYQ QV+ N +A+ ++ GYKIV+GG++NHL LVDL ++ G A+ L I N Sbjct: 286 VYQQQVLDNAKAMVKSFLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALGNAHITVN 345 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KN+ P D RS SGLR+GTPAL RG+ + Q+ A ++ I+ + + T Sbjct: 346 KNSVPNDPRSPFVTSGLRIGTPALARRGV---NAQQSAELALWMCDVLDAIKDEAKLATT 402 Query: 445 LKEFKERLA 453 + K ++A Sbjct: 403 ITAVKVKVA 411 >5VC2-A nrPDB Length = 424 Score = 330 bits (845), Expect = 1e-90, Method: Compositional matrix adjust. Identities = 180/432 (41%), Positives = 267/432 (61%), Gaps = 29/432 (6%) Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81 +A L+ +D E++ +I +E RQ LE+IASEN+ +V+EA+GS L NKY+EGYP +R Sbjct: 9 MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKR 68 Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141 YYGG E +D++E+L +RA + + C NVQ +SGS AN AVY AL++P+ +I+G+ Sbjct: 69 YYGGCEVVDKIESLAIERAKKLF----NCQFANVQAHSGSQANNAVYHALLKPYDKILGM 124 Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201 DL GGHLTHG K+S T ++S Y VN D GYI+Y++ + A+ P++I+ G Sbjct: 125 DLSCGGHLTHG-----AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCG 178 Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261 S Y R +++ + R+IADE GA L+ D+AH++GLV PF HCHVV++TTHKTLRG Sbjct: 179 FSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRG 238 Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321 R G+I T E + + I+ A+FPG QGGP H IA AV K+ + Sbjct: 239 PRGGIIL-----------TNDE---EIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLK 284 Query: 322 LEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACS 381 EFK Y V +N + L++AL E +K+V+GG+ NHL+L+D K G A+ L Sbjct: 285 PEFKAYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAG 344 Query: 382 IACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQ----KVAHFIHRGIELTLQIQ 436 I NKNT PG+ RS SG+R+G+ AL++RG+ K+F+ K++ ++ ++LQ+ Sbjct: 345 ITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLH 404 Query: 437 SDTGVRATLKEF 448 ++A +F Sbjct: 405 VKEELKAMANQF 416 >4OTL-A nrPDB Length = 423 Score = 327 bits (839), Expect = 5e-90, Method: Compositional matrix adjust. Identities = 185/428 (43%), Positives = 256/428 (59%), Gaps = 26/428 (6%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + + D E++ I++E+ RQ +ELIASEN+ S AV+ A GS L NKY+EGYPG+RYYGG Sbjct: 17 IANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 76 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D +E L R Q + + NVQP SGS AN V+ A+++P IMG+ L Sbjct: 77 CEYVDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 132 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + +F + Y +N + I+YD E+ A PKLI+AG S + Sbjct: 133 GGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYDAAEKLANEHKPKLIVAGASAF 186 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 + +++ RL KIA GAYLM DMAH +GL+AAGV P+P H VTTTTHK+LRG R G Sbjct: 187 ALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 246 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I + E INSA+FPG+QGGP H IA AVA K+A++ EFK Sbjct: 247 VILMKA---------------EYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFK 291 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 YQ +VV N R L+E L + G +IV+G +++H++LVDLR+K G AE L A I N Sbjct: 292 EYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVN 351 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KN P D SG+RLG+PA+T+RG + ++V + I +E + VRA Sbjct: 352 KNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQ 411 Query: 445 LKEFKERL 452 + E +R Sbjct: 412 VAELTKRF 419 >4BHD-A nrPDB Length = 428 Score = 202 bits (514), Expect = 3e-52, Method: Compositional matrix adjust. Identities = 143/436 (32%), Positives = 224/436 (51%), Gaps = 41/436 (9%) Query: 33 VYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDEL 92 + ++ K+ R ++LIASEN S AV EA + ++Y+EG PG+R Y G ++IDE+ Sbjct: 9 IRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEV 68 Query: 93 ETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHG 152 ETLC + + + +K + NVQP SG AN AV+ A +P ++M L +PDGGH++H Sbjct: 69 ETLCIELSKELFKAE----HANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHW 124 Query: 153 FMTDKKKISATSIF-FESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEY 211 K+SA I + + + +P+ I+ D + + PKLI+ G S + Sbjct: 125 ------KVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPV 178 Query: 212 ARLRKIADENGAYLMADMAHISGLVAAGVVPSPF-EHCHVVTTTTHKTLRGCRAGMIFYR 270 A + A E GA + D AH+ GL+A P E + +THKT G + G+I Sbjct: 179 ADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTT 238 Query: 271 KGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF-KVYQH 329 K ++ D I+S VFPG+ H H AG+A+AL A LEF + Y Sbjct: 239 K--ENADK-------------IDSHVFPGVVSNHHLHHKAGLAIAL--AEMLEFGEAYAK 281 Query: 330 QVVANCRALSEALTELGYKIVTGGSD---NHLILVDLRSKGT---DGGRAEKVLEACSIA 383 QV+ N +AL++AL E G+ ++ D +H +++D+ S K+ E +I Sbjct: 282 QVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANII 341 Query: 384 CNKNTCPGD--RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441 NKN P D ++ PSG+RLGT T G+ EK+ +++A F+ R + + + V Sbjct: 342 LNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKR---IAIDKEKPEKV 398 Query: 442 RATLKEFKERLAGDKY 457 R +KEF + + Y Sbjct: 399 REDVKEFAKEYSTIHY 414 >5HSI-A nrPDB Length = 634 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 15/189 (7%) Query: 59 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY 118 + VL+ L + + + RY+G ETL AL AY W N Y Sbjct: 72 KTVLDQLSERIRTESVPWHSAGRYWGHMNS----ETLMP--ALLAYNY-AMLWNGNNVAY 124 Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKIS-ATSIFFESMPY---KV 174 SPA + + + R+MG D G + G + + + + A +I +S+P+ +V Sbjct: 125 ESSPATSQMEEEVGQEFARLMGYDYGWGHIVADGSLANLEGLWYARNI--KSLPFAMKEV 182 Query: 175 NPD--TGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHI 232 NP+ G +++ L + L AG+ AR K G +L+ H Sbjct: 183 NPELVAGKSDWELLNMPTKEIMDLLENAGSQIDEVKKRSARSGKNLQRLGKWLVPQTKHY 242 Query: 233 SGLVAAGVV 241 S + AA ++ Sbjct: 243 SWMKAADII 251 >3H9N-A nrPDB Length = 177 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%) Query: 273 VKSVDPKTGKEILYNLESLINSAVFPGLQGGPHN-HAIAGVAVALKQAMTL 322 +K VD + +IL N+E ++ +VFP L+ G + H + G V + T+ Sbjct: 63 LKGVDDREAAQILANVEIGVDLSVFPELEEGDYYWHDLIGCTVVNLEGYTM 113 >3VKQ-A nrPDB Length = 591 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 7/99 (7%) Query: 280 TGKEILYNLESLINSAVFPGLQGGPH--NHAIAGVAVALK--QAMTLEFKVYQHQVVANC 335 G LY + + A P + G N + G A + +A+ L+ V VV C Sbjct: 259 VGSHDLYEHPHINDLAYMPATKDGRFGFNLLVGGFFSAKRCDEAIPLDAWVPADDVVPVC 318 Query: 336 RALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374 RA+ EA +LG++ G ++ + G +G RAE Sbjct: 319 RAILEAFRDLGFR---GNRQKCRMMWLIDELGVEGFRAE 354 >3T2C-A nrPDB Length = 407 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 5/47 (10%) Query: 233 SGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPK 279 SGL A G V F H H+V H +RG AG + + + SVDP+ Sbjct: 243 SGLPAVGEVLEAFAHPHLV----HGWMRGSHAGPLMPARFI-SVDPE 284 >2RAG-A nrPDB Length = 417 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 6/40 (15%) Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSP 244 + RNL+ ARL+KIAD GA I+ + PSP Sbjct: 259 HPRNLDDARLKKIADAGGAIC------INSIYLTDTTPSP 292 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1BJ4-A nrPDB 789 0.0 1RVY-A nrPDB 769 0.0 1EJI-A nrPDB 749 0.0 5X3V-A nrPDB 702 0.0 5Z0Y-A nrPDB 683 0.0 6CCZ-A nrPDB 665 0.0 5XMU-A nrPDB 625 e-179 4O6Z-A nrPDB 621 e-178 4P3M-A nrPDB 612 e-175 2DKJ-A nrPDB 610 e-175 1YJS-A nrPDB 607 e-174 5VMB-A nrPDB 606 e-174 4J5U-A nrPDB 603 e-173 3N0L-A nrPDB 601 e-172 3G8M-A nrPDB 598 e-171 3GBX-A nrPDB 598 e-171 3PGY-A nrPDB 597 e-171 3ECD-A nrPDB 591 e-169 4OTL-A nrPDB 586 e-168 5VC2-A nrPDB 580 e-166 4WXB-A nrPDB 564 e-161 3H7F-A nrPDB 561 e-160 4BHD-A nrPDB 471 e-133 Sequences not found previously or not previously below threshold: 3TQX-A nrPDB 54 2e-07 1M6S-A nrPDB 44 1e-04 3WY7-A nrPDB 43 3e-04 1CS1-A nrPDB 43 4e-04 4BMK-A nrPDB 40 0.002 2X8U-A nrPDB 40 0.002 3A2B-A nrPDB 39 0.005 2AEV-A nrPDB 39 0.005 2BWN-A nrPDB 38 0.008 3NNK-A nrPDB 38 0.008 1FC4-A nrPDB 37 0.014 3OP7-A nrPDB 37 0.016 4AOA-A nrPDB 36 0.045 1PQU-A nrPDB 34 0.11 3BB8-A nrPDB 34 0.14 6ONN-A nrPDB 34 0.16 5JAY-A nrPDB 33 0.23 6NPB-A nrPDB 33 0.23 3TRI-A nrPDB 33 0.26 3WPR-A nrPDB 33 0.28 5K1R-A nrPDB 33 0.29 5XT5-A nrPDB 33 0.31 5JWG-A nrPDB 33 0.39 3WGB-A nrPDB 33 0.39 6G21-A nrPDB 32 0.42 2OKJ-A nrPDB 32 0.49 5HH9-A nrPDB 32 0.60 3Q8X-B nrPDB 32 0.69 5TXT-B nrPDB 32 0.70 3WPA-A nrPDB 32 0.70 1XI9-A nrPDB 32 0.77 1GC4-A nrPDB 32 0.80 2OGE-A nrPDB 30 1.7 5W70-A nrPDB 30 1.8 1RVG-A nrPDB 30 1.9 5OFO-C nrPDB 30 2.1 4CIU-A nrPDB 30 2.1 1JBK-A nrPDB 30 2.3 5O5C-A nrPDB 30 2.8 2YWH-A nrPDB 30 2.8 6C9E-A nrPDB 30 2.9 2FJK-A nrPDB 29 4.6 5X8P-8 nrPDB 28 9.0 >1BJ4-A nrPDB Length = 470 Score = 789 bits (2037), Expect = 0.0, Method: Composition-based stats. Identities = 467/470 (99%), Positives = 467/470 (99%) Query: 11 DADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 70 DADLWSSHD MLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN Sbjct: 1 DADLWSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 60 Query: 71 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 130 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA Sbjct: 61 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 120 Query: 131 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 190 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA Sbjct: 121 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 180 Query: 191 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 250 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV Sbjct: 181 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 240 Query: 251 VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIA 310 VTTTTHKTLRGCRAGMIFYRKGVKSVDP TGKEILYNLESLINSAVFPGLQGGPHNHAIA Sbjct: 241 VTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIA 300 Query: 311 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 370 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG Sbjct: 301 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 360 Query: 371 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE Sbjct: 361 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 420 Query: 431 LTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 480 LTLQIQSDTGV ATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL Sbjct: 421 LTLQIQSDTGVAATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 470 >1RVY-A nrPDB Length = 483 Score = 769 bits (1986), Expect = 0.0, Method: Composition-based stats. Identities = 445/480 (92%), Positives = 462/480 (96%), Gaps = 1/480 (0%) Query: 5 VNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEA 64 VNGA +DA LWSSH++MLAQPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEA Sbjct: 4 VNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEA 63 Query: 65 LGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPAN 124 LGSCLNNKYS+GYPGQRYYGGTE IDELETLCQKRALQAY LDPQCWGVNVQPYSGSPAN Sbjct: 64 LGSCLNNKYSQGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPAN 123 Query: 125 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYD 184 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESM YKVNPDTGYI+YD Sbjct: 124 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYD 183 Query: 185 QLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSP 244 +LEENARLFHPKLIIAGTSCYSRNL+Y RLRKIADENGAYLMADMAHISGLV AGVVPSP Sbjct: 184 RLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSP 243 Query: 245 FEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGP 304 FEHCHVVTTTTHKTLRGCRAGMIFYR+GV+SVDPKTGKEILYNLESLINSAVFPGLQGGP Sbjct: 244 FEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGP 303 Query: 305 HNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR 364 HNHAIAGVAVALKQAMT EFK YQ QVVANCRALS AL ELGYKIVTGGSDNHLILVDLR Sbjct: 304 HNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLR 363 Query: 365 SKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 424 SKGTDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLEKDFQKVAHF Sbjct: 364 SKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 423 Query: 425 IHRGIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483 IHRGIELT+QIQ DTG RATLKEFKE+LAGD K+Q AV+ALR+EVESFA+LFPLPGLP F Sbjct: 424 IHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGLPGF 483 >1EJI-A nrPDB Length = 478 Score = 749 bits (1935), Expect = 0.0, Method: Composition-based stats. Identities = 435/477 (91%), Positives = 454/477 (95%), Gaps = 1/477 (0%) Query: 8 AHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGS 67 A +DA LW+SH+KML+QPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEALGS Sbjct: 2 ADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGS 61 Query: 68 CLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAV 127 LNNKYSEGYPGQRYYGGTEFIDELE LCQKRALQAY LDPQCWGVNVQPYSGSPANFAV Sbjct: 62 SLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAV 121 Query: 128 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLE 187 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKV P+TGYINYDQLE Sbjct: 122 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLE 181 Query: 188 ENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEH 247 ENA LFHPKLIIAGTSCYSRNL+YARLRKIAD+NGAYLMADMAHISGLVAAGVVPSPFEH Sbjct: 182 ENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEH 241 Query: 248 CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNH 307 CHVVTTTTHKTLRGCRAGMIFYRKGV+SVDPKTGKE Y LESLINSAVFPGLQGGPHNH Sbjct: 242 CHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNH 301 Query: 308 AIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKG 367 AIAGVAVALKQAMT EFK+YQ QV+ANCRALS+ALTELGYKIVTGGSDNHLIL+DLRSKG Sbjct: 302 AIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKG 361 Query: 368 TDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHR 427 TDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLE+DFQKVAHFIHR Sbjct: 362 TDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHR 421 Query: 428 GIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483 GIELTLQIQS +ATLKEFKE+LAGD K Q+AV LREEVE+FAS F LPGLPDF Sbjct: 422 GIELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPDF 478 >5X3V-A nrPDB Length = 496 Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats. Identities = 302/458 (65%), Positives = 365/458 (79%), Gaps = 4/458 (0%) Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 + L DSD E++ ++++E +RQ GLELIASENF SRA LEALGSCLNN+YSEGYPG+RYY Sbjct: 26 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNRYSEGYPGKRYY 85 Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 GG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++PH RIMGLDL Sbjct: 86 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 145 Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203 PDGGHLTHG+M+D K+ISATSIFFESMPYK+NP TG I+Y+QL ARLF P+LIIAGTS Sbjct: 146 PDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTS 205 Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263 Y+R ++YAR+R++ DE A+L+ADMAHISGLVAA V+PSPF+H +VTTTTHKTLRG R Sbjct: 206 AYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGAR 265 Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323 +G+IFYRKGVK+VDPKTG+EI Y E IN AVFP LQGGPHNHAIA VAVALKQA T Sbjct: 266 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 325 Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383 F+ Y QV+ N RA+++AL E GY +V+GG+DNHL+LVDLR KG DG RAE+VLE SI Sbjct: 326 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 385 Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKNTCPGDRSA+ P GLRLG PALTSR E DF++V FI G+ + L+++S T A Sbjct: 386 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT---A 442 Query: 444 TLKEFKERLAGDKYQAA-VQALREEVESFASLFPLPGL 480 L++FK L D + + LR+ VE FA FP+PG Sbjct: 443 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 480 >5Z0Y-A nrPDB Length = 470 Score = 683 bits (1762), Expect = 0.0, Method: Composition-based stats. Identities = 260/466 (55%), Positives = 346/466 (74%), Gaps = 3/466 (0%) Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNK 72 L H +M+ L ++D EV IIK E +RQ+ + LIASENF S +V +ALG+ + NK Sbjct: 5 ALSPEHKQMVEGHLAETDPEVNQIIKDEVDRQKHSIVLIASENFTSTSVFDALGTPMCNK 64 Query: 73 YSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALV 132 YSEGYPG RYYGG E ID +E LCQ+RAL+A+ LD WGVNVQ SGSPAN VY A++ Sbjct: 65 YSEGYPGARYYGGNEHIDRMEILCQQRALKAFHLDGSRWGVNVQTLSGSPANLQVYQAIM 124 Query: 133 EPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARL 192 +PH R+MGLDLP GGHL+HG+ TD +KISA S +FE+MPY+V+ +TG I+YD LE+ A L Sbjct: 125 KPHDRLMGLDLPHGGHLSHGYQTDTRKISAVSTYFETMPYRVDLETGIIDYDMLEKTAVL 184 Query: 193 FHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVT 252 + PK+++AGTS Y R ++Y R+R+IAD+ GAYL+ DMAHISGL+AAGV+PSPFE+ +VT Sbjct: 185 YRPKVLVAGTSAYCRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVT 244 Query: 253 TTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGV 312 TTTHK+LRG R MIF+RKGV+SV+PKTGKEI Y+LE+ IN +VFPG QGGPHNH IA + Sbjct: 245 TTTHKSLRGPRGAMIFFRKGVRSVNPKTGKEIYYDLENPINFSVFPGHQGGPHNHTIAAL 304 Query: 313 AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGR 372 A ALKQA T EFK YQ QV+ N +AL LGYK+V+ G+D+H++LV L+ K DG R Sbjct: 305 ATALKQAATPEFKQYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGAR 364 Query: 373 AEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELT 432 E V E +IA NKN+ PGDRSAL P G+R+G PA+T+RG E+DF K+A++I + ++ Sbjct: 365 IETVCENINIALNKNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYA 424 Query: 433 LQIQSDTGVRAT-LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477 ++QS+ + A LK+FK ++A + + L+ E+ ++A FPL Sbjct: 425 KKVQSELPIEANKLKDFKAKIAEGSDE--ITQLKNEISAWAGEFPL 468 >6CCZ-A nrPDB Length = 455 Score = 665 bits (1715), Expect = 0.0, Method: Composition-based stats. Identities = 274/467 (58%), Positives = 344/467 (73%), Gaps = 18/467 (3%) Query: 19 DKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYP 78 + L L ++D +V+ II KE +RQ LELIASENF S+AV+EA+GSCL NKYSEG P Sbjct: 2 NAFLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLP 61 Query: 79 GQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRI 138 G+RYYGG E IDELE LCQ+RAL A+ LD WGVNVQP SGSPANFAVYTA+++PH RI Sbjct: 62 GKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRI 121 Query: 139 MGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLI 198 MGLDLP GGHL+HGFMT K+++S TSI+FESMPY+++ TG I+YD LE+ A LF PKLI Sbjct: 122 MGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLI 181 Query: 199 IAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKT 258 IAG S Y R+++YAR RKIAD GA+LM DMAH+SGL+AA V+ PFE +VTTTTHK+ Sbjct: 182 IAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKS 241 Query: 259 LRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ 318 LRG R GMIF++K +LES IN+AVFPGLQGGPHNH I G+AV LK Sbjct: 242 LRGPRGGMIFFKKDAV---------HGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKY 292 Query: 319 AMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLE 378 A + +FK YQ+QVVANCRAL+ L E YK+V+GGSDNHL+LVDLR G DG R EK+L+ Sbjct: 293 AQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILD 352 Query: 379 ACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQ-- 436 SI NKN+ PGD+SAL P G+R+G+PA+T+RGL EK+F+ +A IH G+ ++L+ + Sbjct: 353 MASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSL 412 Query: 437 -SDTGVRATLKEF--KERLAGDKYQAAVQALREEVESFASLFPLPGL 480 S T V+ L E GDK V LR +VE+ A+ +P+PG+ Sbjct: 413 VSGTKVQDFLNFVLAPEFPLGDK----VSNLRRKVEALATQYPIPGV 455 >5XMU-A nrPDB Length = 442 Score = 625 bits (1611), Expect = e-179, Method: Composition-based stats. Identities = 214/455 (47%), Positives = 294/455 (64%), Gaps = 17/455 (3%) Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83 +PL+ D E+++I+ E RQR + LIASEN + AV E LG+ ++NKYSEGYP +RYY Sbjct: 5 EPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSNKYSEGYPKKRYY 64 Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143 GG +FID++E LCQKRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L Sbjct: 65 GGNDFIDKIEELCQKRALEAFNVSDEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHL 124 Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203 GGHLTHGF +KKK+S TS FES YK N GY++ D + E A F PK+II G + Sbjct: 125 CSGGHLTHGFFDEKKKVSITSDMFESKLYKCN-SQGYVDLDAVREMALSFKPKVIICGYT 183 Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263 Y R+++Y + R+I DE AYL AD++HIS VA ++ +PF H VVTTTTHK LRG R Sbjct: 184 SYPRDIDYQQFRQICDEVNAYLFADISHISSFVACNILNNPFLHADVVTTTTHKILRGPR 243 Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323 + +IF+ K+ +E INSAVFP QGGPHN+ IA VA LK+ + Sbjct: 244 SALIFFN-----------KKRNPGIEQKINSAVFPSFQGGPHNNKIAAVACQLKEVHSPA 292 Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383 FK Y QV+ N +AL++AL +VT G+DNHLI+VDLR G + ++ A +++ Sbjct: 293 FKEYTQQVLLNSKALAKALISKQIDLVTNGTDNHLIVVDLRKFSITGSKLQETCNAINVS 352 Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKNT P D + PSG+R+GTPA+T+RG EKD + +A + R I++T+ +Q G + Sbjct: 353 LNKNTIPSDVDCVSPSGVRIGTPAMTTRGAKEKDMEFIADVLARAIKITVDLQEQYGKK- 411 Query: 444 TLKEFKERLAGDKYQAAVQALREEVESFASLFPLP 478 L +FK+ L G+ A +Q L++EV ++A P P Sbjct: 412 -LVDFKKGLPGN---AQLQQLKQEVVTWAGALPFP 442 >4O6Z-A nrPDB Length = 480 Score = 621 bits (1602), Expect = e-178, Method: Composition-based stats. Identities = 207/453 (45%), Positives = 287/453 (63%), Gaps = 17/453 (3%) Query: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84 PL+ D E++++++KE NRQ + LIASEN + AV E LG ++NKYSEGYP +RYYG Sbjct: 44 PLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRYYG 103 Query: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144 G +++D++E LC KRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L Sbjct: 104 GNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHLC 163 Query: 145 DGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSC 204 GGHLTHGF +KKK+S TS FES YK N + GY++ + + A F PK+II G + Sbjct: 164 SGGHLTHGFFDEKKKVSITSDLFESKLYKCNSE-GYVDMESVRNLALSFQPKVIICGYTS 222 Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 264 Y R+++Y R+I DE AYL AD++HIS VA ++ +PF + VVTTTTHK LRG R+ Sbjct: 223 YPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKILRGPRS 282 Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324 +IF+ K+ ++ INS+VFP QGGPHN+ IA VA LK+ T EF Sbjct: 283 ALIFFN-----------KKRNPGIDQKINSSVFPSFQGGPHNNKIAAVACQLKEVNTPEF 331 Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384 K Y QV+ N +AL+E L + +VT G+DNHLI+VDLR G + ++ A +IA Sbjct: 332 KEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCNAINIAL 391 Query: 385 NKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 NKNT P D + PSG+R+GTPALT+RG EKD + +A + + I LT ++Q G + Sbjct: 392 NKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQKYGKK-- 449 Query: 445 LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477 L +FK+ L + + L++EV +A P Sbjct: 450 LVDFKKGLVNN---PKIDELKKEVVQWAKNLPF 479 >4P3M-A nrPDB Length = 429 Score = 612 bits (1578), Expect = e-175, Method: Composition-based stats. Identities = 189/441 (42%), Positives = 256/441 (58%), Gaps = 26/441 (5%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + D D E++ I E RQ +ELIASEN+ S V+EA GS L NKY+EGYPG+RYYGG Sbjct: 8 IADYDPELWQSITDEVQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D E+L +RA + D NVQP+SGS AN AVY AL P I+G+ L Sbjct: 68 CEYVDVAESLAIERAKSLFGADY----ANVQPHSGSQANAAVYQALCAPGDTILGMSLAH 123 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG +S + + ++ Y + P+TG ++Y ++E A P +IIAG S Y Sbjct: 124 GGHLTHG-----SHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSAY 178 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 S +++A+ R+IAD+ GAYL DMAH++GLVAAG+ P+P VVTTTTHKTL G R G Sbjct: 179 SGIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKTLGGPRGG 238 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I + +E +NSAVFPG QGGP H IA AVA K+ EF Sbjct: 239 LILAKANEA-------------IEKKLNSAVFPGQQGGPLMHVIAAKAVAFKECAEPEFA 285 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 VYQ QV+ N +A+ ++ GYKIV+GG++NHL LVDL ++ G A+ L I N Sbjct: 286 VYQQQVLDNAKAMVKSFLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALGNAHITVN 345 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KN+ P D RS SGLR+GTPAL RG+ + Q+ A ++ I+ + + T Sbjct: 346 KNSVPNDPRSPFVTSGLRIGTPALARRGV---NAQQSAELALWMCDVLDAIKDEAKLATT 402 Query: 445 LKEFKERLAGDKYQAAVQALR 465 + K ++A V L Sbjct: 403 ITAVKVKVAALCKACPVYGLE 423 >2DKJ-A nrPDB Length = 407 Score = 610 bits (1574), Expect = e-175, Method: Composition-based stats. Identities = 205/452 (45%), Positives = 265/452 (58%), Gaps = 51/452 (11%) Query: 28 DSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTE 87 D ++ +I E RQR GLELIASENF S+ V EA+GS L NKY+EGYPG RYYGG E Sbjct: 6 KRDEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCE 65 Query: 88 FIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGG 147 ID +E+L +RA + W NVQP+SGS AN AVY AL+EP +MG+DL GG Sbjct: 66 VIDRVESLAIERAKALFGA---AW-ANVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGG 121 Query: 148 HLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSR 207 HLTHG +++ + ++ + Y V PDT I+ +++ A PK+I+AG S Y R Sbjct: 122 HLTHG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPR 176 Query: 208 NLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMI 267 ++ R+IADE GAYL+ DMAH +GLVAAG+ P+P + HVVT+TTHKTLRG R G+I Sbjct: 177 FWDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLI 236 Query: 268 FYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVY 327 S DP+ GK I+ +FPG+QGGP H IAG AVA +A+ EFK Y Sbjct: 237 L------SNDPELGK--------RIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEY 282 Query: 328 QHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKN 387 VV N + L+E L GY+IVTGG+DNHL LVDLR KG G AE+ L+A I NKN Sbjct: 283 SRLVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKN 342 Query: 388 TCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLK 446 P D + SG+R+GTPA+T+RG ++ VA I R + Sbjct: 343 AIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRAL----------------- 385 Query: 447 EFKERLAGDKYQAAVQALREEVESFASLFPLP 478 + +ALREEV A P+P Sbjct: 386 ----------LEGPSEALREEVRRLALAHPMP 407 >1YJS-A nrPDB Length = 419 Score = 607 bits (1566), Expect = e-174, Method: Composition-based stats. Identities = 192/439 (43%), Positives = 269/439 (61%), Gaps = 32/439 (7%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 L D +V+ I++E RQ +ELIASENF SRAV+EA GS L NKY+EGYPG+RYYGG Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D +E L ++RA Q + + NVQP+SG+ AN AVY ++E ++G++L Sbjct: 64 CEYVDIVEELARERAKQLFGAE----HANVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + + + + Y V+P+T I+YD + E ARL PKLI+A S Y Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAAASAY 174 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 R +++A+ R+IADE GAYLM DMAHI+GLVAAG+ P+P + H VTTTTH+TLRG R G Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGG 234 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 MI ++ I+ A+FPG+QGGP H IA AVA +A+ +FK Sbjct: 235 MILCQE---------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDDFK 279 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 Y +VV N + L+ AL G+ +V+GG+DNHL+LVDLR + G AEKVL+ I N Sbjct: 280 AYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVN 339 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KNT P D S SG+R+GT A+T+RG ++ ++A I + + G Sbjct: 340 KNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIAAIIGLVL-------KNVGSEQA 392 Query: 445 LKEFKERLAGDKYQAAVQA 463 L+E ++R+A + A Sbjct: 393 LEEARQRVAALTDPTSRSA 411 >5VMB-A nrPDB Length = 425 Score = 606 bits (1563), Expect = e-174, Method: Composition-based stats. Identities = 186/430 (43%), Positives = 261/430 (60%), Gaps = 23/430 (5%) Query: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84 + + D E+ I E RQ +ELIASEN+ S AV+EA GS L NKY+EGYPG+RYYG Sbjct: 14 SISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYG 73 Query: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144 G EF+D +E + RA + + D NVQP++GS AN AVY AL+ P ++G+ L Sbjct: 74 GCEFVDVIEQMAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLNPGDTVLGMSLA 129 Query: 145 DGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSC 204 GGHLTHG K+S + + ++ Y +N +TG I+Y+++E A P++I+AG S Sbjct: 130 HGGHLTHG-----AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSA 184 Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 264 YSR +++ R R IAD+ GAYL DMAH++GLVAAGV P+P + V TTTTHKTLRG R+ Sbjct: 185 YSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRS 244 Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324 G+I + +E + SAVFPG QGGP HAIA A+ K+AM+ +F Sbjct: 245 GLILAKANE-------------EIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDF 291 Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384 K YQ QVV N +A++E GY +V+GG+DNHL L+ L + G A+ L A I Sbjct: 292 KAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITV 351 Query: 385 NKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKN+ P D RS SG+R+GTPA+T+RG E + +++A +I I+ + V+A Sbjct: 352 NKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADVIDSKGDEKVIADVKA 411 Query: 444 TLKEFKERLA 453 ++ + Sbjct: 412 KVEAVCAKFP 421 >4J5U-A nrPDB Length = 420 Score = 603 bits (1555), Expect = e-173, Method: Composition-based stats. Identities = 201/460 (43%), Positives = 267/460 (58%), Gaps = 43/460 (9%) Query: 21 MLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQ 80 + L ++D E+ IIK E RQ +ELIASENF S AVLEA G+ L NKY+EGYP + Sbjct: 3 IFNNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSK 62 Query: 81 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMG 140 R+Y G E +D+ E L +R + + C NVQP+SGS AN AVY AL++P ++G Sbjct: 63 RFYNGCEEVDKAENLAIERVKKLF----NCKYANVQPHSGSQANQAVYLALLQPGDTVLG 118 Query: 141 LDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIA 200 + L GGHLTHG + + +F ++ Y VN +T I+YD++E A L PKL+IA Sbjct: 119 MSLDSGGHLTHGAAP-----NMSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIA 173 Query: 201 GTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLR 260 G S Y RN+++A+ R+I D+ GAY MAD+AHI+GLVA G SP + H VT+TTHKTLR Sbjct: 174 GFSAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLR 233 Query: 261 GCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAM 320 G R G+I S D + G INSA+FPGLQGGP H IA AVA + + Sbjct: 234 GPRGGLIL------SNDEEIGH--------KINSALFPGLQGGPLMHIIAAKAVAFLENL 279 Query: 321 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380 E+K Y QV++N +AL+ +L E GY I+TGG+DNH++LVDLR G G A L+ Sbjct: 280 QPEYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRA 339 Query: 381 SIACNKNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDT 439 I CNKN P D S SG+RLGTPA T+RG EKDF V H + ++ + ++ Sbjct: 340 GITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMVADILDGLKNNEDNS 399 Query: 440 GVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPG 479 + Q + EV LFP G Sbjct: 400 ALE-------------------QQVLNEVTKLIELFPFYG 420 >3N0L-A nrPDB Length = 417 Score = 601 bits (1550), Expect = e-172, Method: Composition-based stats. Identities = 193/431 (44%), Positives = 263/431 (61%), Gaps = 25/431 (5%) Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82 A L+ D E++++ KE RQ GLE+IASENF V+E +GS L NKY+EGYPG+RY Sbjct: 3 AMSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRY 62 Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142 YGG EF+DE+ETL +R + + C NVQP SGS AN VY AL+ P +I+G+D Sbjct: 63 YGGCEFVDEIETLAIERCKKLF----NCKFANVQPNSGSQANQGVYAALINPGDKILGMD 118 Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202 L GGHLTHG K+S++ +ES Y V D G I+Y+++ E A+ PKLI+ G Sbjct: 119 LSHGGHLTHG-----AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGA 172 Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262 S Y+R +++A+ R+IADE GAYL AD+AHI+GLV AG PSPF + HVV++TTHKTLRG Sbjct: 173 SAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGP 232 Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322 R G+I L INSA+FPG+QGGP H IA AV K ++ Sbjct: 233 RGGIIMTNDE--------------ELAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNLSD 278 Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382 E+KVY QV N + L+ L + +K+V+ G+DNHL+L+ + G A+ L I Sbjct: 279 EWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGI 338 Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441 NKNT PG+ RS SGLRLGTPALT+RG EK+ + V+++I ++ + + Sbjct: 339 TANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYIADILDDVNNEKLQENI 398 Query: 442 RATLKEFKERL 452 + LK+ Sbjct: 399 KQELKKLASNF 409 >3G8M-A nrPDB Length = 417 Score = 598 bits (1543), Expect = e-171, Method: Composition-based stats. Identities = 193/432 (44%), Positives = 267/432 (61%), Gaps = 23/432 (5%) Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82 + D D E++ +++E RQ +ELIASEN+ S V++A GS L NK++EGYPG+RY Sbjct: 5 EMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKFAEGYPGKRY 64 Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142 YGG E++D +E L RA + + D NVQP+SGS ANFAVYTAL+EP ++G++ Sbjct: 65 YGGCEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMN 120 Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202 L GGHLTHG ++ + + +PY ++ TG+I+Y LE+ A+ PK+II G Sbjct: 121 LAHGGHLTHG-----SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGF 174 Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262 S YS +++A++R+IAD GAYL DMAH++GLVAAGV P+P H HVVTTTTHKTL G Sbjct: 175 SAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGP 234 Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322 R G+I + G + L +NSAVFPG QGGP H IAG AVALK+AM Sbjct: 235 RGGLILAKGGSE------------ELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEP 282 Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382 EFK YQ QV N +A+ E E GYK+V+GG+DNHL LVDL K G A+ L +I Sbjct: 283 EFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANI 342 Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441 NKN+ P D +S SG+R+GTPA+T RG E + +++A ++ ++ + Sbjct: 343 TVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERI 402 Query: 442 RATLKEFKERLA 453 + + + R Sbjct: 403 KGKVLDICARYP 414 >3GBX-A nrPDB Length = 420 Score = 598 bits (1543), Expect = e-171, Method: Composition-based stats. Identities = 191/432 (44%), Positives = 270/432 (62%), Gaps = 23/432 (5%) Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82 + D D E++ +++E RQ +ELIASEN+ S V++A GS L NKY+EGYPG+RY Sbjct: 8 EMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRY 67 Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142 YGG E++D +E L RA + + D NVQP+SGS ANFAVYTAL++P ++G++ Sbjct: 68 YGGCEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMN 123 Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202 L GGHLTHG ++ + + +PY ++ ++G I+YD++ + A+ PK+II G Sbjct: 124 LAQGGHLTHG-----SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGF 177 Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262 S YS +++A++R+IAD GAYL DMAH++GL+AAGV P+P H HVVTTTTHKTL G Sbjct: 178 SAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGP 237 Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322 R G+I K G E LY +NSAVFP QGGP H IAG AVALK+AM Sbjct: 238 RGGLIL---------AKGGDEELY---KKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEP 285 Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382 EFKVYQ QV N +A+ E GYK+V+GG++NHL L+DL K G A+ L +I Sbjct: 286 EFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANI 345 Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441 NKN+ P D +S SG+R+G+PA+T RG E + +++A ++ ++ + V Sbjct: 346 TVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDNINDEATIERV 405 Query: 442 RATLKEFKERLA 453 +A + + R Sbjct: 406 KAKVLDICARFP 417 >3PGY-A nrPDB Length = 415 Score = 597 bits (1539), Expect = e-171, Method: Composition-based stats. Identities = 192/440 (43%), Positives = 263/440 (59%), Gaps = 33/440 (7%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + D + I++E RQ +ELIASENF S AV+EA GS L NKY+EGYPG+RYYGG Sbjct: 7 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 66 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 EF+D E++ RA + + VNVQP+SG AN AVY +E ++G++L Sbjct: 67 CEFVDVTESIAIDRAKALFGAE----HVNVQPHSGPQANMAVYLVALEMGDTVLGMNLSH 122 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + F+ + Y V+ DT INYD++ + A PKLI+AG S Y Sbjct: 123 GGHLTHG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAY 177 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 SR +++ + ++IADE A LM DMAHI+GLVAAG+ P+P E+ VTTTTHKTLRG R G Sbjct: 178 SRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 237 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 MI ++ + I+ +FPG+QGGP H IA AVA +A+ FK Sbjct: 238 MILCKE---------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFK 282 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR-SKGTDGGRAEKVLEACSIAC 384 YQ QVV N + L+EAL G++IV+GG+DNHL+ VD++ S G G AE+ L++ I C Sbjct: 283 TYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITC 342 Query: 385 NKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443 NKNT P D SG+RLGTPA T+RG EK F++VA I ++ + Sbjct: 343 NKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKD-------EE 395 Query: 444 TLKEFKERLAGDKYQAAVQA 463 L++ KER+A + + Sbjct: 396 KLQQAKERVAKLTAEYPLYQ 415 >3ECD-A nrPDB Length = 425 Score = 591 bits (1524), Expect = e-169, Method: Composition-based stats. Identities = 205/464 (44%), Positives = 264/464 (56%), Gaps = 42/464 (9%) Query: 15 WSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 74 S+ + +Q L + D V I KE RQ+ +ELIASEN SRAVL+A GS L NKY+ Sbjct: 2 MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYA 61 Query: 75 EGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEP 134 EGYPG+RYYGG EF DE+E L +R + + NVQP+SG+ AN AV AL +P Sbjct: 62 EGYPGKRYYGGCEFADEVEALAIERVKRLFNA----GHANVQPHSGAQANGAVMLALAKP 117 Query: 135 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFH 194 ++G+ L GGHLTHG K + + +F ++ Y V+ DT I+YDQ+E A+ Sbjct: 118 GDTVLGMSLDAGGHLTHG-----AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHK 172 Query: 195 PKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 254 P LIIAG S Y R L++AR R IAD GA LM DMAHI+G++AAG +P EH HVVT+T Sbjct: 173 PSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTST 232 Query: 255 THKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 314 THKTLRG R G + + INSAVFPGLQGGP H IAG AV Sbjct: 233 THKTLRGPRGGFVLTNDE--------------EIAKKINSAVFPGLQGGPLMHVIAGKAV 278 Query: 315 ALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374 A +A+T +FK Y +V+AN +AL + L G +VTGG+DNHL+LVDLR KG G + E Sbjct: 279 AFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVE 338 Query: 375 KVLEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTL 433 + LE I CNKN P D SG+RLGTPA T+RG +F++V I E Sbjct: 339 QALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFE--- 395 Query: 434 QIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPL 477 + GD +R E+ + FP+ Sbjct: 396 -------------ALRTNPEGDHATEQR--VRREIFALCERFPI 424 >4OTL-A nrPDB Length = 423 Score = 586 bits (1511), Expect = e-168, Method: Composition-based stats. Identities = 185/429 (43%), Positives = 256/429 (59%), Gaps = 26/429 (6%) Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85 + + D E++ I++E+ RQ +ELIASEN+ S AV+ A GS L NKY+EGYPG+RYYGG Sbjct: 17 IANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 76 Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145 E++D +E L R Q + + NVQP SGS AN V+ A+++P IMG+ L Sbjct: 77 CEYVDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 132 Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GGHLTHG ++ + +F + Y +N + I+YD E+ A PKLI+AG S + Sbjct: 133 GGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYDAAEKLANEHKPKLIVAGASAF 186 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265 + +++ RL KIA GAYLM DMAH +GL+AAGV P+P H VTTTTHK+LRG R G Sbjct: 187 ALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 246 Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325 +I + E INSA+FPG+QGGP H IA AVA K+A++ EFK Sbjct: 247 VILMKA---------------EYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFK 291 Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 YQ +VV N R L+E L + G +IV+G +++H++LVDLR+K G AE L A I N Sbjct: 292 EYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVN 351 Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KN P D SG+RLG+PA+T+RG + ++V + I +E + VRA Sbjct: 352 KNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQ 411 Query: 445 LKEFKERLA 453 + E +R Sbjct: 412 VAELTKRFP 420 >5VC2-A nrPDB Length = 424 Score = 580 bits (1495), Expect = e-166, Method: Composition-based stats. Identities = 178/433 (41%), Positives = 265/433 (61%), Gaps = 29/433 (6%) Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81 +A L+ +D E++ +I +E RQ LE+IASEN+ +V+EA+GS L NKY+EGYP +R Sbjct: 9 MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKR 68 Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141 YYGG E +D++E+L +RA + + C NVQ +SGS AN AVY AL++P+ +I+G+ Sbjct: 69 YYGGCEVVDKIESLAIERAKKLF----NCQFANVQAHSGSQANNAVYHALLKPYDKILGM 124 Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201 DL GGHLTHG K+S T ++S Y VN D GYI+Y++ + A+ P++I+ G Sbjct: 125 DLSCGGHLTHG-----AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCG 178 Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261 S Y R +++ + R+IADE GA L+ D+AH++GLV PF HCHVV++TTHKTLRG Sbjct: 179 FSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRG 238 Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321 R G+I + + I+ A+FPG QGGP H IA AV K+ + Sbjct: 239 PRGGIILTNDE--------------EIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLK 284 Query: 322 LEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACS 381 EFK Y V +N + L++AL E +K+V+GG+ NHL+L+D K G A+ L Sbjct: 285 PEFKAYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAG 344 Query: 382 IACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQ----KVAHFIHRGIELTLQIQ 436 I NKNT PG+ RS SG+R+G+ AL++RG+ K+F+ K++ ++ ++LQ+ Sbjct: 345 ITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLH 404 Query: 437 SDTGVRATLKEFK 449 ++A +F Sbjct: 405 VKEELKAMANQFP 417 >4WXB-A nrPDB Length = 428 Score = 564 bits (1454), Expect = e-161, Method: Composition-based stats. Identities = 182/422 (43%), Positives = 264/422 (62%), Gaps = 25/422 (5%) Query: 27 KDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGT 86 K D E++N I E+ RQ+ +ELIASEN S+AV+ A G+ L NKY+EGYPG+RYYGGT Sbjct: 21 KAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRYYGGT 80 Query: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146 ID +ETL +RA + + NVQP+SGS AN AVY +L++P +MG+DL G Sbjct: 81 AVIDVVETLAIERAKKLFGA----KFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAG 136 Query: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206 GHLTHG +S + + + Y V+ ++ ++YD + A+ PKLI+AG S YS Sbjct: 137 GHLTHG-----APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYS 191 Query: 207 RNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGM 266 R +++A+ R+IAD GAYLM DMAHI+GLVA+G PSP + HV TTTTHKTLRG R G+ Sbjct: 192 RIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGL 251 Query: 267 IFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKV 326 I ++ +NSAVFPGLQGGP H IA AVALK+A+ FK Sbjct: 252 ILTDDE--------------DIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKE 297 Query: 327 YQHQVVANCRALSEALTEL-GYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385 Y V+ N A+++ + +++++GG++NHL LVD+ +G A+ VLE +I N Sbjct: 298 YGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLN 357 Query: 386 KNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444 KN+ P ++ S + SG+R+G+PA+TSRG+ E + +++A ++ +E + + +R Sbjct: 358 KNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGD 417 Query: 445 LK 446 +K Sbjct: 418 VK 419 >3H7F-A nrPDB Length = 447 Score = 561 bits (1445), Expect = e-160, Method: Composition-based stats. Identities = 194/462 (41%), Positives = 259/462 (56%), Gaps = 54/462 (11%) Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81 ++ PL + D ++ ++ KE RQR LE+IASENF RAVL+A GS L NKY+EG PG+R Sbjct: 22 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 81 Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141 YYGG E +D +E L + RA + + NVQP+SG+ AN AV AL+ P R++GL Sbjct: 82 YYGGCEHVDVVENLARDRAKALFGAE----FANVQPHSGAQANAAVLHALMSPGERLLGL 137 Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201 DL +GGHLTHG +++ + +E+ Y V+P T I+ D + A F PK+IIAG Sbjct: 138 DLANGGHLTHGM-----RLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAG 192 Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261 S Y R L++A R IADE GA L+ DMAH +GLVAAG+ PSP H VV+TT HKTL G Sbjct: 193 WSAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG 252 Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321 R+G+I ++ INSAVFPG QGGP H IAG AVALK A T Sbjct: 253 GRSGLIVGKQ---------------QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAAT 297 Query: 322 LEFKVYQHQVVANCRALSEALT-----ELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKV 376 EF Q + ++ R +++ L + G +V+GG+D HL+LVDLR DG AE + Sbjct: 298 PEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDL 357 Query: 377 LEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 435 L I N+N P D R + SGLR+GTPAL +RG + +F +VA I + + Sbjct: 358 LHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATGSSV 417 Query: 436 QSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPL 477 V AL++ A FPL Sbjct: 418 D------------------------VSALKDRATRLARAFPL 435 >4BHD-A nrPDB Length = 428 Score = 471 bits (1213), Expect = e-133, Method: Composition-based stats. Identities = 143/443 (32%), Positives = 222/443 (50%), Gaps = 41/443 (9%) Query: 27 KDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGT 86 D + ++ K+ R ++LIASEN S AV EA + ++Y+EG PG+R Y G Sbjct: 3 SDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGC 62 Query: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146 ++IDE+ETLC + + + +K + NVQP SG AN AV+ A +P ++M L +PDG Sbjct: 63 KYIDEVETLCIELSKELFKAE----HANVQPTSGVVANLAVFFAETKPGDKLMALSVPDG 118 Query: 147 GHLTHGFMTDKKKISATSIF-FESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205 GH++H K+SA I + + + +P+ I+ D + + PKLI+ G S + Sbjct: 119 GHISHW------KVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLF 172 Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPF-EHCHVVTTTTHKTLRGCRA 264 A + A E GA + D AH+ GL+A P E + +THKT G + Sbjct: 173 PFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQG 232 Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324 G+I K I+S VFPG+ H H AG+A+AL A LEF Sbjct: 233 GVILTTK---------------ENADKIDSHVFPGVVSNHHLHHKAGLAIAL--AEMLEF 275 Query: 325 -KVYQHQVVANCRALSEALTELGYKIVTGGSD---NHLILVDLRSKGT---DGGRAEKVL 377 + Y QV+ N +AL++AL E G+ ++ D +H +++D+ S K+ Sbjct: 276 GEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMY 335 Query: 378 EACSIACNKNTCPGD--RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 435 E +I NKN P D ++ PSG+RLGT T G+ EK+ +++A F+ R + + Sbjct: 336 EEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKR---IAIDK 392 Query: 436 QSDTGVRATLKEFKERLAGDKYQ 458 + VR +KEF + + Y Sbjct: 393 EKPEKVREDVKEFAKEYSTIHYS 415 >3TQX-A nrPDB Length = 399 Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 58/313 (18%), Positives = 112/313 (35%), Gaps = 46/313 (14%) Query: 123 ANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYIN 182 AN ++ L+ P I+ L H + D ++ ++ Y+ + + Sbjct: 115 ANGGLFETLLGPEDAIIS------DELNHASIIDGIRLC------KAQRYRYKNNAMG-D 161 Query: 183 YDQLEENARLF--HPKLIIAG--TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA 238 + + A KLI S + + +AD+ A +M D +H G + Sbjct: 162 LEAKLKEADEKGARFKLIATDGVFSMDGIIADLKSICDLADKYNALVMVDDSHAVGFIGE 221 Query: 239 GVVPSPFEHC------HVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLI 292 +P E+C ++T T K L G G Y G K + L S Sbjct: 222 NGRGTP-EYCGVADRVDILTGTLGKALGGASGG---YTSGHKEIIEWLRNRSRPYLFS-- 275 Query: 293 NSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTG 352 + V P I ++ + + + E + Q+ N R + +LG+++V G Sbjct: 276 -NTVAP---------VIVATSLKVLELLKTEGPQLRKQLQENSRYFRAGMEKLGFQLVPG 325 Query: 353 GSDNHLIL-VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSR 411 NH I+ V L A+ +L+ I + P + + +R+ A+ ++ Sbjct: 326 ---NHPIIPVMLGDAQLATNMADHLLQE-GIYVVGFSYP--VVPMGKARIRVQMSAVHTQ 379 Query: 412 GLLEKDFQKVAHF 424 L++ + Sbjct: 380 QQLDRAIEAFGQV 392 >1M6S-A nrPDB Length = 347 Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 56/323 (17%), Positives = 111/323 (34%), Gaps = 56/323 (17%) Query: 79 GQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRI 138 G YG I+ELE L A + + + + SG+ N A + + Sbjct: 30 GDDVYGEDPTINELERL----AAETFGKEAALFVP-----SGTMGNQVSIMAHTQRGDEV 80 Query: 139 MGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENAR---LFHP 195 + L H+ ++ A ++ MP+ V G ++ D + + R + P Sbjct: 81 I---LEADSHI------FWYEVGAMAVLSGVMPHPVPGKNGAMDPDDVRKAIRPRNIHFP 131 Query: 196 KL-IIAGTSCYSR----NLEYARLRKI---ADENGAYLMADMAHI-SGLVAAGVVPSPFE 246 + +IA + ++R + +++I A E+G + D A I + +A+GV P + Sbjct: 132 RTSLIAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGV---PVK 188 Query: 247 ----HCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQG 302 + V K L ++ + K K + + Q Sbjct: 189 EYAGYADSVMFCLSKGLCAPVGSVVVGDRDFIERARKARKMLGGGMR-----------QA 237 Query: 303 GPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVD 362 G +A + M K N R L+ L E+GY + +++++ Sbjct: 238 G----VLAAAGIIALTKMVDRLKEDHE----NARFLALKLKEIGYSVNPEDVKTNMVILR 289 Query: 363 LRSKGTDGGRAEKVLEACSIACN 385 + + + L + N Sbjct: 290 TDNLKVNAHGFIEALRNSGVLAN 312 >3WY7-A nrPDB Length = 404 Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 36/177 (20%), Positives = 64/177 (36%), Gaps = 23/177 (12%) Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT 178 SG AN AL P L L+H + D ++S + P++ Sbjct: 125 SGYTANLGALVALSGPG------SLIVSDALSHASLVDACRLSRARVV--VSPHRDVDAV 176 Query: 179 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRK---IADENGAYLMADMAHISGL 235 + EE A ++ S +S + + A LR + +GA L+ D AH G+ Sbjct: 177 DAALAARTEERA-------VVVTESVFSADGDLAPLRDLHAVCRRHGALLLVDEAHGLGV 229 Query: 236 VAAG----VVPSPFEHC-HVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYN 287 + +V TTT G + G + + V++ T + +++ Sbjct: 230 RGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVLGPEAVRAHLIDTARSFIFD 286 >1CS1-A nrPDB Length = 386 Score = 42.7 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 29/170 (17%) Query: 97 QKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTD 156 +RAL + + V +G A V T ++P ++ GG Sbjct: 57 VQRAL----AELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGG--------- 103 Query: 157 KKKISATSIFFESMPYKVNPDTGYINY--DQLEENARLFHPKLIIAGTSCYS--RNLEYA 212 + F+S+ + +++ +Q A PKL++ + R ++ A Sbjct: 104 ------SYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIA 157 Query: 213 RLRKIADENGAYLMADMAHISGLVAAGVVPSPFE-HCHVVTTTTHKTLRG 261 ++ +A E GA + D +S + +P +V + K L G Sbjct: 158 KICHLAREVGAVSVVDNTFLS-----PALQNPLALGADLVLHSCTKYLNG 202 >4BMK-A nrPDB Length = 442 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 80/412 (19%), Positives = 149/412 (36%), Gaps = 69/412 (16%) Query: 11 DADLWSSHDKMLAQPLKDSDVEV---YNIIKKESN-------RQRVGLELIASENFA--- 57 + DL S D ++A+ K D V + I+ ++ R + + L+ + N+ Sbjct: 42 ERDLLSKFDGLIAERQKLLDSGVTDPFAIVMEQVKSPTEAVIRGKDTI-LLGTYNYMGMT 100 Query: 58 -SRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQ 116 V+ A G K+ G G R GT F D +E ++AL+ + G V Sbjct: 101 FDPDVIAA-GKEALEKFGSGTNGSRMLNGT-FHDHME---VEQALRDF---YGTTGAIVF 152 Query: 117 PYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNP 176 +G AN + + L ++ L H + + S+ Sbjct: 153 -STGYMANLGIISTLAGKGEYVI---LDADSHASIYDGCQQGNAEIVRFRHNSVE----- 203 Query: 177 DTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRK---IADENGAYLMADMAHIS 233 + D+ KL++ YS + A L++ +A ++GA ++ D AH Sbjct: 204 -----DLDKRLGRLPKEPAKLVVLEG-VYSMLGDIAPLKEMVAVAKKHGAMVLVDEAHSM 257 Query: 234 GLVAA---GVV-PSPFEH-CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNL 288 G GV E V T ++ G G + S PK L Sbjct: 258 GFFGPNGRGVYEAQGLEGQIDFVVGTFSASV-GTVGGFVV------SNHPKFEAVRLACR 310 Query: 289 ESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYK 348 + +++ P +A ++++ MT K + ++ +N RAL L +G++ Sbjct: 311 PYIFTASLPPS--------VVATATTSIRKLMTAHEK--RERLWSNARALHGGLKAMGFR 360 Query: 349 IVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSG 400 + T D+ ++ V L + + +L+ + N R P+G Sbjct: 361 LGTETCDSAIVAVMLEDQEQAAMMWQALLDG-GLYVN-----MARPPATPAG 406 >2X8U-A nrPDB Length = 412 Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 62/350 (17%), Positives = 114/350 (32%), Gaps = 61/350 (17%) Query: 64 ALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPA 123 A G +++ G G R GT + C+ + Y + +G A Sbjct: 65 AAGKQALDEFGSGTTGSRVLNGTYQGHKA---CEDALKEFYGTEHAIVFS-----TGYQA 116 Query: 124 NFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINY 183 N + + L I+ L H + S+ ++ G + Sbjct: 117 NLGMISTLAGKGDYII---LDADSHASIYDGCWLGDAEIVRFRHNSVE-DLDKRLGRLPA 172 Query: 184 DQLEENARLFHPKLIIAGTSCYSRNLEYARLRK---IADENGAYLMADMAHISGLVA--- 237 + + YS + A L++ ++ ++GA ++ D AH G Sbjct: 173 EAGKLVVLE----------GVYSMMGDIAPLQEMVAVSKKHGAMILVDEAHGMGFFGEHG 222 Query: 238 ------AGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESL 291 AGV V T K++ G G S PK L + Sbjct: 223 RGVFEEAGVEAD----VDFVVGTFSKSV-GTVGGF------CVSNHPKFEVLRLVCRPYV 271 Query: 292 INSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVT 351 +++ P +A A ++++ M K + + N R L + L ++GYK+ T Sbjct: 272 FTASLPPS--------VVATAATSIRKLMHAGDK--RAHLWKNSRRLHQGLRDMGYKLGT 321 Query: 352 GGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGL 401 + + +I V L + +LE + N R P+G+ Sbjct: 322 ETAQSAIIAVILTDMAQAVALWQGLLE-AGLYVN-----TARPPATPAGM 365 >3A2B-A nrPDB Length = 398 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 64/345 (18%), Positives = 119/345 (34%), Gaps = 65/345 (18%) Query: 72 KYSEGYPGQRYYGGTE--FIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYT 129 KY G G R+ GT ++ E L +A L +G +N + Sbjct: 72 KYGTGCAGSRFLNGTLDIHVELEEKLSAYVGKEAAILFS----------TGFQSNLGPLS 121 Query: 130 ALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEEN 189 L+ + I+ LD D H + D ++S + + + Y N N + L Sbjct: 122 CLMGRNDYIL-LDERD-----HASIIDGSRLSFS----KVIKYGHN------NMEDLRAK 165 Query: 190 AR---LFHPKLIIAG--TSCYSRNLEYARLRKIADENGAYLMADMAHISGLV-----AAG 239 KLI S + L IA+E A +M D AH G++ Sbjct: 166 LSRLPEDSAKLICTDGIFSMEGDIVNLPELTSIANEFDAAVMVDDAHSLGVIGHKGAGTA 225 Query: 240 VVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPG 299 + ++ T K+L G + V + ++++ +++ P Sbjct: 226 SHFGLNDDVDLIMGTFSKSLAS-LGGFVAGDADVIDFLKHNARSVMFS------ASMTP- 277 Query: 300 LQGGPHNHAIAGVAVALK--QAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNH 357 A VA LK + + E + ++ N L + G+ + G +++ Sbjct: 278 ----------ASVASTLKALEIIQNE-PEHIEKLWKNTDYAKAQLLDHGFDL--GATESP 324 Query: 358 LILVDLRSKGTDGGRAEKVLEACSIACN---KNTCPGDRSALRPS 399 ++ + +RS K+L+ + N P + S +R S Sbjct: 325 ILPIFIRSNEKT-FWVTKMLQDDGVFVNPVVSPAVPAEESLIRFS 368 >2AEV-A nrPDB Length = 374 Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 21/107 (19%), Positives = 43/107 (40%), Gaps = 8/107 (7%) Query: 197 LIIAGTSCYSRNLEYARLRKI---ADENGAYLMADMAHISGLVAAGVVPSPFE---HCHV 250 +II G++ + +E +K+ A A + D A SG + P + Sbjct: 144 VIITGSTMDLKVIELENFKKVINTAKNKEAIVFVDDA--SGARVRLLFNQPPALKLGADL 201 Query: 251 VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVF 297 V T+T K + G R G++ +K + G + + + + ++ Sbjct: 202 VVTSTDKLMEGPRGGLLAGKKELVDKIYIEGTKFGLEAQPPLLAGIY 248 >2BWN-A nrPDB Length = 401 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 49/218 (22%), Positives = 77/218 (35%), Gaps = 31/218 (14%) Query: 195 PKLIIAGTSCYSRNLEYARLRKIAD---ENGAYLMADMAHISGLV----AAGVVPSPFEH 247 PKLI A S YS + ++ +++I D E GA D H G+ A H Sbjct: 179 PKLI-AFESVYSMDGDFGPIKEICDIAEEFGALTYIDEVHAVGMYGPRGAGVAERDGLMH 237 Query: 248 -CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHN 306 + T K G G I + VD + + + A+ G Q Sbjct: 238 RIDIFNGTLAKAY-GVFGGYI--AASARMVDAVRSYAPGFIFSTSLPPAIAAGAQA---- 290 Query: 307 HAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSK 366 +IA + A Q + Q+ + + L L LG I+ GS H++ V + Sbjct: 291 -SIAFLKTAEGQKLRD-----AQQM--HAKVLKMRLKALGMPIIDHGS--HIVPVVIGDP 340 Query: 367 GTDGGRAEKVLEACSIAC---NKNTCP--GDRSALRPS 399 ++ +L + N T P +R PS Sbjct: 341 VHTKAVSDMLLSDYGVYVQPINFPTVPRGTERLRFTPS 378 >3NNK-A nrPDB Length = 411 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 72/214 (33%), Gaps = 36/214 (16%) Query: 57 ASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQ 116 A VL A+ S L +Y P +Y E + R ++ + W + V Sbjct: 24 ADPRVLRAMSSQLIGQYD---PAMTHYMN-------EVMALYRG--VFRTE-NRWTMLVD 70 Query: 117 PYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNP 176 S + A+ + + P +++ +P G H ++ A E +P+ Sbjct: 71 GTSRAGIE-AILVSAIRPGDKVL---VPVFGRFGHLLCEIARRCRAEVHTIE-VPWG--- 122 Query: 177 DTGYINYDQLEENARLFHPKLI--IAGTSCYSRNLEYARLRKIADENGAYLMADMAHISG 234 DQ+E+ + P+L+ + G + + A L +I A D Sbjct: 123 --EVFTPDQVEDAVKRIRPRLLLTVQGDTSTTMLQPLAELGEICRRYDALFYTD------ 174 Query: 235 LVAAGVVPSPFE----HCHVVTTTTHKTLRGCRA 264 A + +P E V+ K L G Sbjct: 175 -ATASLGGNPLETDVWGLDAVSAGMQKCLGGPSG 207 >1FC4-A nrPDB Length = 401 Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 73/215 (33%), Gaps = 31/215 (14%) Query: 182 NYDQLEENARLFHPK----LIIAGTSCYSRNLEYARLR---KIADENGAYLMADMAHISG 234 + +LE + ++IA +S + A L+ +AD+ A +M D +H G Sbjct: 160 DMQELEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVG 219 Query: 235 LVAAG-----VVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLE 289 V ++T T K L G G RK V + + Sbjct: 220 FVGENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSR------- 272 Query: 290 SLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349 P L AI ++ + + M + ++ AN R E ++ G+ + Sbjct: 273 --------PYLFSNSLAPAIVAASIKVLE-MVEAGSELRDRLWANARQFREQMSAAGFTL 323 Query: 350 VTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384 G+D H I+ + + + L+ I Sbjct: 324 --AGAD-HAIIPVMLGDAVVAQKFARELQKEGIYV 355 >3OP7-A nrPDB Length = 375 Score = 37.3 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 19/121 (15%) Query: 115 VQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKV 174 +Q + AN V +L+EP ++ L + T+ + D K S+ E +++ Sbjct: 85 LQTNGATGANLLVLYSLIEPGDHVISL------YPTYQQLYDIPK----SLGAEVDLWQI 134 Query: 175 NPDTGYINYDQLEENARLFHP--KLIIAGTSCYSR--NLE---YARLRKIADENGAYLMA 227 + G++ LE+ +L P K+I + ++ L +IA E GAY+++ Sbjct: 135 EEENGWL--PDLEKLRQLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEVGAYILS 192 Query: 228 D 228 D Sbjct: 193 D 193 >4AOA-A nrPDB Length = 454 Score = 35.8 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 44/119 (36%), Gaps = 16/119 (13%) Query: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPD 177 SG+ AN TA + GR + G H G + + S T++ F+ + N Sbjct: 150 NSGTEANLMALTAALHFTGRRKIVVFSGGYH--GGVLGFGARPSPTTVPFDFLVLPYN-- 205 Query: 178 TGYINYDQLEENARLFHPKLIIA------GTS-CYSRNLEY-ARLRKIADENGAYLMAD 228 + P++ + G S C ++ LR+ A + GA L+ D Sbjct: 206 ----DAQTARAQIERHGPEIAVVLVEPMQGASGCIPGQPDFLQALRESATQVGALLVFD 260 >1PQU-A nrPDB Length = 371 Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 29/162 (17%), Positives = 51/162 (31%), Gaps = 18/162 (11%) Query: 316 LKQAMTLEFKVYQHQVVA-----NCRALSEALTELGYKIVTGGSDNHLILVDLRSK--GT 368 L+QA++ E K ++ + ++ + GGS L+ K Sbjct: 183 LEQAVSSELKDPASSILDIERKVTAKMRADNFPTDNFGAALGGS-----LIPWIDKLLPE 237 Query: 369 DGGRAEKVLEACS----IACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 424 G E+ + + N P D +R LR + A T + + +++ Sbjct: 238 TGQTKEEWKGYAETNKILGLSDNPIPVDGLCVRIGALRCNSQAFTIKLKKDLPLEEIEQI 297 Query: 425 IHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALRE 466 I E I TL+E V LR+ Sbjct: 298 IASHNEWVKVI--PNDKEITLRELTPAKVTGTLSVPVGRLRK 337 >3BB8-A nrPDB Length = 437 Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 32/167 (19%), Positives = 56/167 (33%), Gaps = 21/167 (12%) Query: 118 YSGSPANFAVYTAL---------VEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFE 168 SGS AN TAL ++P ++ + GF T + Sbjct: 84 TSGSSANLLALTALTSPKLGVRALKPGDEVIT--------VAAGFPTTVNPTIQNGLI-- 133 Query: 169 SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMAD 228 + V+ T +N +E A K I+ + + A +R++AD+ +L+ D Sbjct: 134 PVFVDVDIPTYNVNASLIEA-AVSDKTKAIMIAHTL-GNLFDLAEVRRVADKYNLWLIED 191 Query: 229 MAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKS 275 G G + F V+ K + G +F + Sbjct: 192 CCDALGSTYDGKMAGTFGDIGTVSFYPAKHITMGEGGAVFTQSAELK 238 >6ONN-A nrPDB Length = 402 Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 20/122 (16%) Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT 178 +G AN A TAL + L H + D ++S I + P+ Sbjct: 119 TGYMANLATLTALAGRGTTLFSDS------LNHASLIDGARLSRADI--QIYPHA----- 165 Query: 179 GYINYDQLEEN--ARLFHPKLIIAG--TSCYSRNLEYARLRKIADENGAYLMADMAHISG 234 + + L A KLI++ S ARL ++A+ +GA+L+ D AH G Sbjct: 166 ---DAEALGAMLEASDAAVKLIVSDTVFSMDGDIAPLARLLELAEHHGAWLVVDDAHGFG 222 Query: 235 LV 236 ++ Sbjct: 223 VL 224 >5JAY-A nrPDB Length = 402 Score = 33.5 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 49/301 (16%), Positives = 104/301 (34%), Gaps = 51/301 (16%) Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT 178 +G AN A TAL + L H + D ++S + Y Sbjct: 119 TGYMANLATLTALAGRGTTLFS------DALNHASLIDGARLSRA----DVQIYP----- 163 Query: 179 GYINYDQLEEN--ARLFHPKLIIAGTSCYSRNLEYA---RLRKIADENGAYLMADMAHIS 233 + + D L A K+I++ + +S + + A RL ++A+++GA+L+ D AH Sbjct: 164 -HCDTDALSAMLEASDADVKVIVSD-TVFSMDGDIAPLPRLLELAEQHGAWLIVDDAHGF 221 Query: 234 GLVA----AGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLE 289 G++ + + ++++ T G + + V + + ++ Sbjct: 222 GVLGPQGRGAIAQAALRSPNLISIGTLDKAAGVSGAFVAAHETVIEWLVQRARPYIFTTA 281 Query: 290 SLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349 S+ +A HA++ + + + Q++ RA+ L + Sbjct: 282 SVPAAA-----------HAVSASLRIIGGEEGDARRAHLQQLIGRTRAM---LKATPWLP 327 Query: 350 VTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSG---LRLGTP 406 V + +++ L+ + P R P+G LR+ Sbjct: 328 VDSHTAVQPLIIGANDATL---EIAATLDRAGL-----WVPAIRPPTVPTGTSRLRISLS 379 Query: 407 A 407 A Sbjct: 380 A 380 >6NPB-A nrPDB Length = 383 Score = 33.5 bits (75), Expect = 0.23, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 25/65 (38%), Gaps = 1/65 (1%) Query: 117 PYSGSPANFAVYTALVE-PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVN 175 P + SP N + + P + L D G LT F + K ++ + +S Y + Sbjct: 44 PETRSPGNGQRLITIGDIPADTRISTALVDDGALTVTFAPEGKTVTFPGKWLKSNAYDTD 103 Query: 176 PDTGY 180 + Sbjct: 104 QSSEV 108 >3TRI-A nrPDB Length = 280 Score = 33.1 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 31/161 (19%), Positives = 56/161 (34%), Gaps = 15/161 (9%) Query: 316 LKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG-----SDNHLILVDLRSKGTDG 370 K+ + Q N + A+ K+V S+ ++++ L + G Sbjct: 45 FKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISL-AVGVTT 103 Query: 371 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430 EK L S P PS +R G L + ++KD + +A I R + Sbjct: 104 PLIEKWLGKASRIVR--AMPN-----TPSSVRAGATGLFANETVDKDQKNLAESIMRAVG 156 Query: 431 LTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESF 471 L + + S+ + A ++AL+E E Sbjct: 157 LVIWVSSEDQIEKIAALSGSGPAYIFLI--MEALQEAAEQL 195 >3WPR-A nrPDB Length = 229 Score = 33.1 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 50/157 (31%), Gaps = 19/157 (12%) Query: 299 GLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIV------TG 352 G GP + G + A+T + S++ G IV Sbjct: 57 GTITGPTYNVAQGNQTNVGDALTA-----LDNAINTAATTSKSTVSNGQNIVVSKSKNAD 111 Query: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRG 412 GSDN+ + + VL I N + + L S G P++T G Sbjct: 112 GSDNYEVSTAKDLTVDSVKAGDTVLNNAGITIGNNAVVLNNTGLTIS----GGPSVTLAG 167 Query: 413 L--LEKDFQKVAHFIH--RGIELTLQIQSDTGVRATL 445 + K Q VA+ ++ + Q + + L Sbjct: 168 IDAGNKTIQNVANAVNATDAVNKGQMKQIEDKIEEIL 204 >5K1R-A nrPDB Length = 480 Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 30/182 (16%), Positives = 59/182 (32%), Gaps = 20/182 (10%) Query: 167 FESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS-RNLE-YARLRKIADENGAY 224 F+ ++P T ++ D + + A + +++ Y ++ L IA E + Sbjct: 171 FDVTVAPIDPVTMQVDADFVRD-AVDANTVMLVGSACNYPYGTIDPIGALSAIAVEKDVW 229 Query: 225 LMADMAHISGLVAAGV---VPS-P-----FEHCHVVTTTTHKTLRGCRAGMIFYRKGVKS 275 L D ++ G P P ++ THK G + G + + Sbjct: 230 LHVDGCLGGWMLPWGEALGYPDIPAFDFRLPGVTSISADTHKFGYGPKGGSVLAWR---- 285 Query: 276 VDPKTGKEILYNLESLINSAVF--PGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVA 333 D + + + + V+ PGL G IA AL+ + + Sbjct: 286 -DASFRRHQYFLMTDWV-GGVYGSPGLTGSRSGGLIAATWAALRSLGREGYLARAKAIFE 343 Query: 334 NC 335 Sbjct: 344 TA 345 >5XT5-A nrPDB Length = 419 Score = 33.1 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 61/170 (35%), Gaps = 19/170 (11%) Query: 114 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK 173 N+ S + AN ++P ++ + ++ + AT + +P + Sbjct: 100 NMVALSYARAN-------LKPGDEVVITYMEHHANIIPWQQA----VKATGATLKYIPLQ 148 Query: 174 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL-EYARLRKIADENGAYLMADMAHI 232 + G I+ + + E + ++ S + + KIA +NGA ++ D A Sbjct: 149 ---EDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQS 205 Query: 233 SGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGK 282 + + V C ++HK + G + Y K + + + Sbjct: 206 TPHMKIDVQD---LDCDFFALSSHK-MCGPTGVGVLYGKKALLENMEPAE 251 >5JWG-A nrPDB Length = 703 Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 13/77 (16%) Query: 19 DKMLAQPLKDSDVEVYNIIKKESNRQR--VGLELIASENFASRAVLEALGSCLNNKYSEG 76 + L + D +V +KKE R + GLE F S L +L + K + Sbjct: 97 NPGLEVEIVDEITDVTAAVKKELERIKKPSGLE------FLSPRYLSSLAPEIVGKKAAS 150 Query: 77 YPGQRY-----YGGTEF 88 PG RY YGG + Sbjct: 151 RPGYRYEIKAFYGGNRY 167 >3WGB-A nrPDB Length = 341 Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 33/202 (16%), Positives = 69/202 (34%), Gaps = 18/202 (8%) Query: 100 ALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKK 159 AL+AY D + SG+ +N + + G L H+ + + Sbjct: 43 ALEAYGADLLGKEAALFVPSGTMSNLLAVMSHCQRGE---GAVLGSAAHI-YRYEAQGSA 98 Query: 160 ISATSIFFESMPYKVNPDTGYINY-DQLEENARLFHPKLIIAGTSCYSR---NLEYAR-L 214 + S+ + +P + + + + + F P ++ + ++ L Y R + Sbjct: 99 V-LGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVCLENTHNGKVLPLPYLREM 157 Query: 215 RKIADENGAYLMADMAHISGLVAAGVVP-----SPFEHCHVVTTTTHKTLRGCRAGMIFY 269 R++ DE+G L D A + V A +PF V+ K L ++ Sbjct: 158 RELVDEHGLQLHLDGARLFNAVVASGHTVRELVAPF---DSVSICLSKGLGAPVGSLLVG 214 Query: 270 RKGVKSVDPKTGKEILYNLESL 291 + + K + + Sbjct: 215 SHAFIARARRLRKMVGGGMRQA 236 >6G21-A nrPDB Length = 507 Score = 32.3 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 54/166 (32%), Gaps = 47/166 (28%) Query: 15 WSSHDKMLAQPLKD---SDVEVYNIIKKESNRQRVGLE-----LIASENFASRAVLEALG 66 WS+H + P+ +++NI KE RQ G++ +I + S VLEA+ Sbjct: 204 WSAHFYSITGPVGSDTYLSPDLWNITHKEILRQCDGIDGAEDGIIEDPSLCSP-VLEAII 262 Query: 67 SCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFA 126 +E G++ + + + P G N Sbjct: 263 CKPGQNTTECLTGKQAH---------------TVREIFS-----------PLYGV--NGT 294 Query: 127 VYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPY 172 + ++P +M + G + ++ ++ + Y Sbjct: 295 LLYPRMQPGSEVMASSIMYNG----------QPFQYSADWYRYVVY 330 >2OKJ-A nrPDB Length = 504 Score = 32.3 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 33/103 (32%), Gaps = 11/103 (10%) Query: 168 ESMPYKVNPDTGYINYDQLEENARLFHPKLII-------AGTSCYSRNLEYARLRKIADE 220 + K N I D E K + AGT+ Y + I ++ Sbjct: 215 NVILIKCNERGKIIPAD-FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEK 273 Query: 221 NGAYLMADMAHISGLVAAGVVP---SPFEHCHVVTTTTHKTLR 260 +L D A GL+ + + E + VT HK + Sbjct: 274 YNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMG 316 >5HH9-A nrPDB Length = 390 Score = 32.0 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 45/258 (17%), Positives = 85/258 (32%), Gaps = 32/258 (12%) Query: 115 VQP----YSGSPAN--FAVYTALV-EPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFF 167 VQP +GS + A+Y L+ +P I+ + T+ + + K T Sbjct: 74 VQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEH--YSTYTTLEYRHKRMGT---- 127 Query: 168 ESMPYKVNPDTGYINYDQLEE-NARLFHPKLIIAGT----SCYSRNLEYARLRKIADENG 222 + + + D ++ D++ A P+ + G S L + K+ E Sbjct: 128 QVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELN 187 Query: 223 AY--------LMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVK 274 + D H G V + F+ C THK L G R + + + Sbjct: 188 QKRDEQDRIIYVVDGVH--GFGVEDVSFADFD-CDYFIAGTHKWLFGPRGTGVIIARSEQ 244 Query: 275 SVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVAN 334 + ++ + + PG G + A + + L Q ++ Sbjct: 245 LQEHLVPSIPTFSRADNFGTLMTPG--GYHAFEHRLALGTAFELHLQLGKAEVQARIHQL 302 Query: 335 CRALSEALTEL-GYKIVT 351 L + L E ++VT Sbjct: 303 NAYLKQRLGEHPKVRLVT 320 >3Q8X-B nrPDB Length = 287 Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 17/101 (16%) Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF- 324 +I +K V+S + ++ + SA+F QG + I KQ F Sbjct: 23 LIQGKKAVESPTAFLLGGQPGSGKTSLRSAIFEETQG----NVIVIDNDTFKQQH-PNFD 77 Query: 325 ---KVYQHQVVAN--------CRALSEALTELGYKIVTGGS 354 K+Y+ VV + A+ L++ GY +V G+ Sbjct: 78 ELVKLYEKDVVKHVTPYSNRMTEAIISRLSDQGYNLVIEGT 118 >5TXT-B nrPDB Length = 491 Score = 31.6 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 14/78 (17%) Query: 182 NYDQLEENARLFH---PKLIIAGTSCYS---RNLEYARLRKIADENGAYLMADMAHISGL 235 + ++LE+ + + PKLI A S YS + ++ +AD+ GA D H GL Sbjct: 173 DLNELEQLLQSYPKSVPKLI-AFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGL 231 Query: 236 V---AAGVVPSPFEHCHV 250 AGV EHC Sbjct: 232 YGPHGAGV----AEHCDF 245 >3WPA-A nrPDB Length = 427 Score = 31.6 bits (70), Expect = 0.70, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 45/136 (33%), Gaps = 17/136 (12%) Query: 299 GLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIV------TG 352 G GP + G + A+T + S++ G IV Sbjct: 57 GTITGPTYNVAQGNQTNVGDALTA-----LDNAINTAATTSKSTVSNGQNIVVSKSKNAD 111 Query: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRG 412 GSDN+ + + VL I N + + L S G P++T G Sbjct: 112 GSDNYEVSTAKDLTVDSVKAGDTVLNNAGITIGNNAVVLNNTGLTIS----GGPSVTLAG 167 Query: 413 L--LEKDFQKVAHFIH 426 + K Q VA+ ++ Sbjct: 168 IDAGNKTIQNVANAVN 183 >1XI9-A nrPDB Length = 406 Score = 31.6 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 28/61 (45%), Gaps = 1/61 (1%) Query: 79 GQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRI 138 G YYG +E + EL +R + +D V V + + A ++ AL++P I Sbjct: 70 GHNYYGDSEGLPELRKAIVEREKRKNGVDITPDDVRVTA-AVTEALQLIFGALLDPGDEI 128 Query: 139 M 139 + Sbjct: 129 L 129 >1GC4-A nrPDB Length = 385 Score = 31.6 bits (70), Expect = 0.80, Method: Composition-based stats. Identities = 42/232 (18%), Positives = 81/232 (34%), Gaps = 52/232 (22%) Query: 33 VYNIIKKESNRQRVGLELIA---------SENFASRAVLEALGSCLNNKYS--EGYPGQR 81 V + K +R G++L+A + A AL KY+ G P R Sbjct: 16 VVAVNAKALELRRQGVDLVALTAGEPDFDTPEHVKEAARRALAQGKT-KYAPPAGIPELR 74 Query: 82 YYGGTEFIDELETLCQK-RALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMG 140 E L +K R + P+ V V GS A F ++ A+++P ++ Sbjct: 75 -----------EALAEKFRRENGLSVTPEETIVTV---GGSQALFNLFQAILDPGDEVIV 120 Query: 141 LDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIA 200 L+ +++ + + + + P+ G++ + A K ++ Sbjct: 121 --------LSPYWVSYPEMVRFAGGV--VVEVETLPEEGFVPDPERVRRAITPRTKALVV 170 Query: 201 G------TSCYSRNLEYA--------RLRKIADENGAYLMADMAHIS-GLVA 237 + Y + + A ++DE +L+ + H S G VA Sbjct: 171 NSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGRVA 222 >2OGE-A nrPDB Length = 399 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 27/133 (20%), Positives = 49/133 (36%), Gaps = 16/133 (12%) Query: 104 YKLDPQCWGVNVQPYSGSPANFAVYTAL-VEPHGRIMGLDLPDGGHLTHGFMTDKKKISA 162 + + V SG A L + P ++ +P +H ++ +SA Sbjct: 72 FAAYCETDHA-VGVNSGMDALQLALRGLGIGPGDEVI---VP-----SHTYIASWLAVSA 122 Query: 163 TSIFFESMPYKVNPDTGYINYDQL-EENARLFHPKLIIAGTSCYSRNLEYARLRKIADEN 221 T + P V P + D L E A + ++ Y + LR++AD + Sbjct: 123 TG----ATPVPVEPHEDHPTLDPLLVEKAITPRTRALLP-VHLYGHPADMDALRELADRH 177 Query: 222 GAYLMADMAHISG 234 G +++ D A G Sbjct: 178 GLHIVEDAAQAHG 190 >5W70-A nrPDB Length = 445 Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 38/177 (21%), Positives = 60/177 (33%), Gaps = 21/177 (11%) Query: 99 RALQAYKLDPQCWGVNVQPYSGSPANFAVYTAL-VEPHGRIM--GLDLPDGGHLTHGFMT 155 RA AY P C V SG+ + A + ++ GL G G Sbjct: 80 RAFAAYNGVPHC----VPAASGTASLMLALEACGIGAGDEVIVPGLSWVASGSTILG--- 132 Query: 156 DKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLR 215 ++A IF + V+PDT ++ + +E +++ YS + L Sbjct: 133 ----VNAVPIFCD-----VDPDTLCLSPEAVEAAITEHTRAIVVV--HLYSALADMDALS 181 Query: 216 KIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKG 272 IA+ +G L+ D A G GV + K L G + R Sbjct: 182 AIAERHGLPLIEDCAQAHGATYRGVKVGALATAGTFSMQHSKVLTSGEGGAVITRDE 238 >1RVG-A nrPDB Length = 305 Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 26/69 (37%), Gaps = 14/69 (20%) Query: 180 YINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239 +I++ +LE ARL L++ G S L R R E G AAG Sbjct: 188 FIDHARLERIARLVPAPLVLHGASAVPPEL-VERFRASGGEIGE-------------AAG 233 Query: 240 VVPSPFEHC 248 + P + Sbjct: 234 IHPEDIKKA 242 >5OFO-C nrPDB Length = 871 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNN- 71 DL ++ P+ D E+ I+ R + LI A++E L + N Sbjct: 171 DLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIING 230 Query: 72 KYSEGYPGQR 81 + EG G+R Sbjct: 231 EVPEGLKGRR 240 >4CIU-A nrPDB Length = 727 Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNN- 71 DL ++ P+ D E+ I+ R + LI A++E L + N Sbjct: 25 DLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIING 84 Query: 72 KYSEGYPGQR 81 + EG G+R Sbjct: 85 EVPEGLKGRR 94 >1JBK-A nrPDB Length = 195 Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%) Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNN- 71 DL ++ P+ D E+ I+ R + LI A++E L + N Sbjct: 11 DLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIING 70 Query: 72 KYSEGYPGQR 81 + EG G+R Sbjct: 71 EVPEGLKGRR 80 >5O5C-A nrPDB Length = 519 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 29/167 (17%), Positives = 62/167 (37%), Gaps = 29/167 (17%) Query: 120 GSPANFAVYT-------ALVEPHGRIMGLDLPDGG--------HLTHGFMTDKKKISATS 164 G+ +N A P I LP L+H + +K ++ Sbjct: 170 GTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSH--FSIQKSMAILG 227 Query: 165 IFFESMPYKVNPDTGY-INYDQLEE-----NARLFHPKLIIA--GTSCYSRNLEYARLRK 216 + ++++ V+ D Y ++ D L++ + P ++A GT+ + + + Sbjct: 228 LGYDAVI-PVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDPLGAISE 286 Query: 217 IADENGAYLMADMAHISGLVAAGVVP---SPFEHCHVVTTTTHKTLR 260 + +G ++ D A+ GL+ + + E VT HK+ Sbjct: 287 LCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHKSFF 333 >2YWH-A nrPDB Length = 600 Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 8/26 (30%), Positives = 14/26 (53%) Query: 117 PYSGSPANFAVYTALVEPHGRIMGLD 142 PY G+ A ++ V+P +IM + Sbjct: 204 PYRGAVAFVRIFDGEVKPGDKIMLMS 229 >6C9E-A nrPDB Length = 422 Score = 29.6 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 42/265 (15%), Positives = 79/265 (29%), Gaps = 32/265 (12%) Query: 134 PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLF 193 P I+ + ++ M KK + P +N G + ++ E Sbjct: 128 PDEEILITHMEHHSNIVPWQMVCKK----MGCKLQVAPISLN---GEVILEEFERKLNEN 180 Query: 194 HPKLIIAGTSCYSRNL-EYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVT 252 + I S + + K+A E GA ++ D A + + V C Sbjct: 181 TKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQD---LDCDFYA 237 Query: 253 TTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGV 312 + HK + G + + K +INS F + H Sbjct: 238 FSGHK-MYGPTGIGVLWGKEELLN----SMTPYQGGGEMINSVSFEATEYAAIPHKFEAG 292 Query: 313 AVALKQAMT-------------LEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLI 359 + A+ Y+ Q++ EA+ GY I+ G + N + Sbjct: 293 TPNIAGAIGLAAAIDYIWSLDLDAIAEYETQLLNYATKAIEAV--KGYNII-GTAANKVP 349 Query: 360 LVDLRSKGTDGGRAEKVLEACSIAC 384 ++ +L++ IA Sbjct: 350 IISFVHGKIHAHDIGTILDSEGIAI 374 >2FJK-A nrPDB Length = 305 Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 14/69 (20%) Query: 180 YINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239 +I++ +L A+L L++ G S + L R R E G A+G Sbjct: 188 FIDHPRLARIAKLVPAPLVLHGASAVPQEL-VERFRAAGGEIGE-------------ASG 233 Query: 240 VVPSPFEHC 248 + P + Sbjct: 234 IHPEDIKKA 242 >5X8P-8 nrPDB Length = 370 Score = 28.1 bits (61), Expect = 9.0, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 35/86 (40%), Gaps = 12/86 (13%) Query: 130 ALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEEN 189 +++P + + L ++ ++S ++ E P + + + +++ EE Sbjct: 261 TVLQPGDTLKVMILSH--------DRERGRVSLSTKKLEPTPGDMIRNPKLV-FEKAEEM 311 Query: 190 ARLFHPKLIIAGTSCYSRNLEYARLR 215 A+ F + IA +R + R + Sbjct: 312 AQTFRQR--IAQAEAMARA-DMLRFQ 334 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.134 0.379 Lambda K H 0.267 0.0414 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 19,863,347 Number of Sequences: 36641 Number of extensions: 842658 Number of successful extensions: 2335 Number of sequences better than 10.0: 69 Number of HSP's better than 10.0 without gapping: 51 Number of HSP's successfully gapped in prelim test: 48 Number of HSP's that attempted gapping in prelim test: 2109 Number of HSP's gapped (non-prelim): 105 length of query: 483 length of database: 10,336,785 effective HSP length: 101 effective length of query: 382 effective length of database: 6,636,044 effective search space: 2534968808 effective search space used: 2534968808 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.1 bits)