BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P34896
(483 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
1BJ4-A nrPDB 971 0.0
1RVY-A nrPDB 900 0.0
1EJI-A nrPDB 883 0.0
5X3V-A nrPDB 637 0.0
6CCZ-A nrPDB 557 e-159
5Z0Y-A nrPDB 549 e-156
5XMU-A nrPDB 418 e-117
4O6Z-A nrPDB 399 e-111
2DKJ-A nrPDB 370 e-103
3ECD-A nrPDB 361 e-100
1YJS-A nrPDB 360 1e-99
4J5U-A nrPDB 359 2e-99
3PGY-A nrPDB 355 2e-98
3N0L-A nrPDB 355 2e-98
3G8M-A nrPDB 343 1e-94
5VMB-A nrPDB 341 5e-94
3H7F-A nrPDB 336 1e-92
3GBX-A nrPDB 336 2e-92
4WXB-A nrPDB 334 5e-92
4P3M-A nrPDB 332 3e-91
5VC2-A nrPDB 330 1e-90
4OTL-A nrPDB 327 5e-90
4BHD-A nrPDB 202 3e-52
5HSI-A nrPDB 30 1.6
3H9N-A nrPDB 29 4.5
3VKQ-A nrPDB 29 5.1
3T2C-A nrPDB 28 6.8
2RAG-A nrPDB 28 8.1
>1BJ4-A nrPDB
Length = 470
Score = 971 bits (2509), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 467/470 (99%), Positives = 467/470 (99%)
Query: 11 DADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 70
DADLWSSHD MLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN
Sbjct: 1 DADLWSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 60
Query: 71 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 130
NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA
Sbjct: 61 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 120
Query: 131 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 190
LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA
Sbjct: 121 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 180
Query: 191 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 250
RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV
Sbjct: 181 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 240
Query: 251 VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIA 310
VTTTTHKTLRGCRAGMIFYRKGVKSVDP TGKEILYNLESLINSAVFPGLQGGPHNHAIA
Sbjct: 241 VTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIA 300
Query: 311 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 370
GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG
Sbjct: 301 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 360
Query: 371 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430
GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE
Sbjct: 361 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 420
Query: 431 LTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 480
LTLQIQSDTGV ATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
Sbjct: 421 LTLQIQSDTGVAATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 470
>1RVY-A nrPDB
Length = 483
Score = 900 bits (2327), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 445/480 (92%), Positives = 462/480 (96%), Gaps = 1/480 (0%)
Query: 5 VNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEA 64
VNGA +DA LWSSH++MLAQPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEA
Sbjct: 4 VNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEA 63
Query: 65 LGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPAN 124
LGSCLNNKYS+GYPGQRYYGGTE IDELETLCQKRALQAY LDPQCWGVNVQPYSGSPAN
Sbjct: 64 LGSCLNNKYSQGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPAN 123
Query: 125 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYD 184
FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESM YKVNPDTGYI+YD
Sbjct: 124 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYD 183
Query: 185 QLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSP 244
+LEENARLFHPKLIIAGTSCYSRNL+Y RLRKIADENGAYLMADMAHISGLV AGVVPSP
Sbjct: 184 RLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSP 243
Query: 245 FEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGP 304
FEHCHVVTTTTHKTLRGCRAGMIFYR+GV+SVDPKTGKEILYNLESLINSAVFPGLQGGP
Sbjct: 244 FEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGP 303
Query: 305 HNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR 364
HNHAIAGVAVALKQAMT EFK YQ QVVANCRALS AL ELGYKIVTGGSDNHLILVDLR
Sbjct: 304 HNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLR 363
Query: 365 SKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 424
SKGTDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLEKDFQKVAHF
Sbjct: 364 SKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 423
Query: 425 IHRGIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483
IHRGIELT+QIQ DTG RATLKEFKE+LAGD K+Q AV+ALR+EVESFA+LFPLPGLP F
Sbjct: 424 IHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGLPGF 483
>1EJI-A nrPDB
Length = 478
Score = 883 bits (2281), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 435/477 (91%), Positives = 454/477 (95%), Gaps = 1/477 (0%)
Query: 8 AHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGS 67
A +DA LW+SH+KML+QPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEALGS
Sbjct: 2 ADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGS 61
Query: 68 CLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAV 127
LNNKYSEGYPGQRYYGGTEFIDELE LCQKRALQAY LDPQCWGVNVQPYSGSPANFAV
Sbjct: 62 SLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAV 121
Query: 128 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLE 187
YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKV P+TGYINYDQLE
Sbjct: 122 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLE 181
Query: 188 ENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEH 247
ENA LFHPKLIIAGTSCYSRNL+YARLRKIAD+NGAYLMADMAHISGLVAAGVVPSPFEH
Sbjct: 182 ENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEH 241
Query: 248 CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNH 307
CHVVTTTTHKTLRGCRAGMIFYRKGV+SVDPKTGKE Y LESLINSAVFPGLQGGPHNH
Sbjct: 242 CHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNH 301
Query: 308 AIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKG 367
AIAGVAVALKQAMT EFK+YQ QV+ANCRALS+ALTELGYKIVTGGSDNHLIL+DLRSKG
Sbjct: 302 AIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKG 361
Query: 368 TDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHR 427
TDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLE+DFQKVAHFIHR
Sbjct: 362 TDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHR 421
Query: 428 GIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483
GIELTLQIQS +ATLKEFKE+LAGD K Q+AV LREEVE+FAS F LPGLPDF
Sbjct: 422 GIELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPDF 478
>5X3V-A nrPDB
Length = 496
Score = 637 bits (1644), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 303/458 (66%), Positives = 365/458 (79%), Gaps = 4/458 (0%)
Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83
+ L DSD E++ ++++E +RQ GLELIASENF SRA LEALGSCLNN+YSEGYPG+RYY
Sbjct: 26 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNRYSEGYPGKRYY 85
Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143
GG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++PH RIMGLDL
Sbjct: 86 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 145
Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203
PDGGHLTHG+M+D K+ISATSIFFESMPYK+NP TG I+Y+QL ARLF P+LIIAGTS
Sbjct: 146 PDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTS 205
Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Y+R ++YAR+R++ DE A+L+ADMAHISGLVAA V+PSPF+H +VTTTTHKTLRG R
Sbjct: 206 AYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGAR 265
Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
+G+IFYRKGVK+VDPKTG+EI Y E IN AVFP LQGGPHNHAIA VAVALKQA T
Sbjct: 266 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 325
Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
F+ Y QV+ N RA+++AL E GY +V+GG+DNHL+LVDLR KG DG RAE+VLE SI
Sbjct: 326 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 385
Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKNTCPGDRSA+ P GLRLG PALTSR E DF++V FI G+ + L+++S T A
Sbjct: 386 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT---A 442
Query: 444 TLKEFKERLAGDKYQAAVQA-LREEVESFASLFPLPGL 480
L++FK L D + A LR+ VE FA FP+PG
Sbjct: 443 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 480
>6CCZ-A nrPDB
Length = 455
Score = 557 bits (1435), Expect = e-159, Method: Compositional matrix adjust.
Identities = 276/461 (59%), Positives = 344/461 (74%), Gaps = 20/461 (4%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
L ++D +V+ II KE +RQ LELIASENF S+AV+EA+GSCL NKYSEG PG+RYYGG
Sbjct: 9 LSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLPGKRYYGG 68
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E IDELE LCQ+RAL A+ LD WGVNVQP SGSPANFAVYTA+++PH RIMGLDLP
Sbjct: 69 NEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRIMGLDLPH 128
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHL+HGFMT K+++S TSI+FESMPY+++ TG I+YD LE+ A LF PKLIIAG S Y
Sbjct: 129 GGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLIIAGASAY 188
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
R+++YAR RKIAD GA+LM DMAH+SGL+AA V+ PFE +VTTTTHK+LRG R G
Sbjct: 189 PRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKSLRGPRGG 248
Query: 266 MIFYRK-GVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324
MIF++K V VD LES IN+AVFPGLQGGPHNH I G+AV LK A + +F
Sbjct: 249 MIFFKKDAVHGVD----------LESAINNAVFPGLQGGPHNHTIGGLAVCLKYAQSPDF 298
Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384
K YQ+QVVANCRAL+ L E YK+V+GGSDNHL+LVDLR G DG R EK+L+ SI
Sbjct: 299 KNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILDMASITL 358
Query: 385 NKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQ---SDTGV 441
NKN+ PGD+SAL P G+R+G+PA+T+RGL EK+F+ +A IH G+ ++L+ + S T V
Sbjct: 359 NKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSLVSGTKV 418
Query: 442 RATLKEF--KERLAGDKYQAAVQALREEVESFASLFPLPGL 480
+ L E GDK V LR +VE+ A+ +P+PG+
Sbjct: 419 QDFLNFVLAPEFPLGDK----VSNLRRKVEALATQYPIPGV 455
>5Z0Y-A nrPDB
Length = 470
Score = 549 bits (1414), Expect = e-156, Method: Compositional matrix adjust.
Identities = 260/465 (55%), Positives = 346/465 (74%), Gaps = 3/465 (0%)
Query: 14 LWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKY 73
L H +M+ L ++D EV IIK E +RQ+ + LIASENF S +V +ALG+ + NKY
Sbjct: 6 LSPEHKQMVEGHLAETDPEVNQIIKDEVDRQKHSIVLIASENFTSTSVFDALGTPMCNKY 65
Query: 74 SEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVE 133
SEGYPG RYYGG E ID +E LCQ+RAL+A+ LD WGVNVQ SGSPAN VY A+++
Sbjct: 66 SEGYPGARYYGGNEHIDRMEILCQQRALKAFHLDGSRWGVNVQTLSGSPANLQVYQAIMK 125
Query: 134 PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLF 193
PH R+MGLDLP GGHL+HG+ TD +KISA S +FE+MPY+V+ +TG I+YD LE+ A L+
Sbjct: 126 PHDRLMGLDLPHGGHLSHGYQTDTRKISAVSTYFETMPYRVDLETGIIDYDMLEKTAVLY 185
Query: 194 HPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTT 253
PK+++AGTS Y R ++Y R+R+IAD+ GAYL+ DMAHISGL+AAGV+PSPFE+ +VTT
Sbjct: 186 RPKVLVAGTSAYCRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVTT 245
Query: 254 TTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVA 313
TTHK+LRG R MIF+RKGV+SV+PKTGKEI Y+LE+ IN +VFPG QGGPHNH IA +A
Sbjct: 246 TTHKSLRGPRGAMIFFRKGVRSVNPKTGKEIYYDLENPINFSVFPGHQGGPHNHTIAALA 305
Query: 314 VALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRA 373
ALKQA T EFK YQ QV+ N +AL LGYK+V+ G+D+H++LV L+ K DG R
Sbjct: 306 TALKQAATPEFKQYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGARI 365
Query: 374 EKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTL 433
E V E +IA NKN+ PGDRSAL P G+R+G PA+T+RG E+DF K+A++I + ++
Sbjct: 366 ETVCENINIALNKNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYAK 425
Query: 434 QIQSDTGVRAT-LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477
++QS+ + A LK+FK ++A + + L+ E+ ++A FPL
Sbjct: 426 KVQSELPIEANKLKDFKAKIAEGSDE--ITQLKNEISAWAGEFPL 468
>5XMU-A nrPDB
Length = 442
Score = 418 bits (1075), Expect = e-117, Method: Compositional matrix adjust.
Identities = 215/455 (47%), Positives = 295/455 (64%), Gaps = 17/455 (3%)
Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83
+PL+ D E+++I+ E RQR + LIASEN + AV E LG+ ++NKYSEGYP +RYY
Sbjct: 5 EPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSNKYSEGYPKKRYY 64
Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143
GG +FID++E LCQKRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L
Sbjct: 65 GGNDFIDKIEELCQKRALEAFNVSDEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHL 124
Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203
GGHLTHGF +KKK+S TS FES YK N GY++ D + E A F PK+II G +
Sbjct: 125 CSGGHLTHGFFDEKKKVSITSDMFESKLYKCN-SQGYVDLDAVREMALSFKPKVIICGYT 183
Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Y R+++Y + R+I DE AYL AD++HIS VA ++ +PF H VVTTTTHK LRG R
Sbjct: 184 SYPRDIDYQQFRQICDEVNAYLFADISHISSFVACNILNNPFLHADVVTTTTHKILRGPR 243
Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
+ +IF+ K +P +E INSAVFP QGGPHN+ IA VA LK+ +
Sbjct: 244 SALIFFN---KKRNP--------GIEQKINSAVFPSFQGGPHNNKIAAVACQLKEVHSPA 292
Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
FK Y QV+ N +AL++AL +VT G+DNHLI+VDLR G + ++ A +++
Sbjct: 293 FKEYTQQVLLNSKALAKALISKQIDLVTNGTDNHLIVVDLRKFSITGSKLQETCNAINVS 352
Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKNT P D + PSG+R+GTPA+T+RG EKD + +A + R I++T+ +Q G +
Sbjct: 353 LNKNTIPSDVDCVSPSGVRIGTPAMTTRGAKEKDMEFIADVLARAIKITVDLQEQYGKK- 411
Query: 444 TLKEFKERLAGDKYQAAVQALREEVESFASLFPLP 478
L +FK+ L G+ A +Q L++EV ++A P P
Sbjct: 412 -LVDFKKGLPGN---AQLQQLKQEVVTWAGALPFP 442
>4O6Z-A nrPDB
Length = 480
Score = 399 bits (1026), Expect = e-111, Method: Compositional matrix adjust.
Identities = 208/453 (45%), Positives = 288/453 (63%), Gaps = 17/453 (3%)
Query: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
PL+ D E++++++KE NRQ + LIASEN + AV E LG ++NKYSEGYP +RYYG
Sbjct: 44 PLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRYYG 103
Query: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144
G +++D++E LC KRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L
Sbjct: 104 GNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHLC 163
Query: 145 DGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSC 204
GGHLTHGF +KKK+S TS FES YK N + GY++ + + A F PK+II G +
Sbjct: 164 SGGHLTHGFFDEKKKVSITSDLFESKLYKCNSE-GYVDMESVRNLALSFQPKVIICGYTS 222
Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 264
Y R+++Y R+I DE AYL AD++HIS VA ++ +PF + VVTTTTHK LRG R+
Sbjct: 223 YPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKILRGPRS 282
Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324
+IF+ K +P ++ INS+VFP QGGPHN+ IA VA LK+ T EF
Sbjct: 283 ALIFFN---KKRNP--------GIDQKINSSVFPSFQGGPHNNKIAAVACQLKEVNTPEF 331
Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384
K Y QV+ N +AL+E L + +VT G+DNHLI+VDLR G + ++ A +IA
Sbjct: 332 KEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCNAINIAL 391
Query: 385 NKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
NKNT P D + PSG+R+GTPALT+RG EKD + +A + + I LT ++Q G +
Sbjct: 392 NKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQKYGKK-- 449
Query: 445 LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477
L +FK+ L + + L++EV +A P
Sbjct: 450 LVDFKKGLVNN---PKIDELKKEVVQWAKNLPF 479
>2DKJ-A nrPDB
Length = 407
Score = 370 bits (950), Expect = e-103, Method: Compositional matrix adjust.
Identities = 206/450 (45%), Positives = 265/450 (58%), Gaps = 51/450 (11%)
Query: 30 DVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFI 89
D ++ +I E RQR GLELIASENF S+ V EA+GS L NKY+EGYPG RYYGG E I
Sbjct: 8 DEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCEVI 67
Query: 90 DELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHL 149
D +E+L +RA + W NVQP+SGS AN AVY AL+EP +MG+DL GGHL
Sbjct: 68 DRVESLAIERAKALFG---AAWA-NVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGGHL 123
Query: 150 THGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL 209
THG +++ + ++ + Y V PDT I+ +++ A PK+I+AG S Y R
Sbjct: 124 THG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPRFW 178
Query: 210 EYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFY 269
++ R+IADE GAYL+ DMAH +GLVAAG+ P+P + HVVT+TTHKTLRG R G+I
Sbjct: 179 DFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLIL- 237
Query: 270 RKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQH 329
S DP+ GK I+ +FPG+QGGP H IAG AVA +A+ EFK Y
Sbjct: 238 -----SNDPELGKR--------IDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEYSR 284
Query: 330 QVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTC 389
VV N + L+E L GY+IVTGG+DNHL LVDLR KG G AE+ L+A I NKN
Sbjct: 285 LVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKNAI 344
Query: 390 PGDRSALR-PSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLKEF 448
P D R SG+R+GTPA+T+RG ++ VA I R +
Sbjct: 345 PFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRAL------------------- 385
Query: 449 KERLAGDKYQAAVQALREEVESFASLFPLP 478
+ +ALREEV A P+P
Sbjct: 386 --------LEGPSEALREEVRRLALAHPMP 407
>3ECD-A nrPDB
Length = 425
Score = 361 bits (927), Expect = e-100, Method: Compositional matrix adjust.
Identities = 200/412 (48%), Positives = 256/412 (62%), Gaps = 24/412 (5%)
Query: 15 WSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 74
S+ + +Q L + D V I KE RQ+ +ELIASEN SRAVL+A GS L NKY+
Sbjct: 2 MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYA 61
Query: 75 EGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEP 134
EGYPG+RYYGG EF DE+E L +R + + NVQP+SG+ AN AV AL +P
Sbjct: 62 EGYPGKRYYGGCEFADEVEALAIERVKRLF----NAGHANVQPHSGAQANGAVMLALAKP 117
Query: 135 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFH 194
++G+ L GGHLTHG K + + +F ++ Y V+ DT I+YDQ+E A+
Sbjct: 118 GDTVLGMSLDAGGHLTHG-----AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHK 172
Query: 195 PKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 254
P LIIAG S Y R L++AR R IAD GA LM DMAHI+G++AAG +P EH HVVT+T
Sbjct: 173 PSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTST 232
Query: 255 THKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 314
THKTLRG R G + + D + K+ INSAVFPGLQGGP H IAG AV
Sbjct: 233 THKTLRGPRGGFVL------TNDEEIAKK--------INSAVFPGLQGGPLMHVIAGKAV 278
Query: 315 ALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374
A +A+T +FK Y +V+AN +AL + L G +VTGG+DNHL+LVDLR KG G + E
Sbjct: 279 AFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVE 338
Query: 375 KVLEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425
+ LE I CNKN P D SG+RLGTPA T+RG +F++V I
Sbjct: 339 QALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLI 390
>1YJS-A nrPDB
Length = 419
Score = 360 bits (923), Expect = 1e-99, Method: Compositional matrix adjust.
Identities = 193/429 (44%), Positives = 269/429 (62%), Gaps = 32/429 (7%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
L D +V+ I++E RQ +ELIASENF SRAV+EA GS L NKY+EGYPG+RYYGG
Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D +E L ++RA Q + + NVQP+SG+ AN AVY ++E ++G++L
Sbjct: 64 CEYVDIVEELARERAKQLFGAE----HANVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + + + + Y V+P+T I+YD + E ARL PKLI+A S Y
Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAAASAY 174
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
R +++A+ R+IADE GAYLM DMAHI+GLVAAG+ P+P + H VTTTTH+TLRG R G
Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGG 234
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
MI ++ I+ A+FPG+QGGP H IA AVA +A+ +FK
Sbjct: 235 MILCQE---------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDDFK 279
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
Y +VV N + L+ AL G+ +V+GG+DNHL+LVDLR + G AEKVL+ I N
Sbjct: 280 AYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVN 339
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KNT P D S SG+R+GT A+T+RG ++ ++A I G+ L + G
Sbjct: 340 KNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIAAII--GLVL-----KNVGSEQA 392
Query: 445 LKEFKERLA 453
L+E ++R+A
Sbjct: 393 LEEARQRVA 401
>4J5U-A nrPDB
Length = 420
Score = 359 bits (921), Expect = 2e-99, Method: Compositional matrix adjust.
Identities = 194/401 (48%), Positives = 253/401 (63%), Gaps = 24/401 (5%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
L ++D E+ IIK E RQ +ELIASENF S AVLEA G+ L NKY+EGYP +R+Y G
Sbjct: 8 LHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSKRFYNG 67
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E +D+ E L +R + + C NVQP+SGS AN AVY AL++P ++G+ L
Sbjct: 68 CEEVDKAENLAIERVKKLF----NCKYANVQPHSGSQANQAVYLALLQPGDTVLGMSLDS 123
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG + + +F ++ Y VN +T I+YD++E A L PKL+IAG S Y
Sbjct: 124 GGHLTHGAAPN-----MSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGFSAY 178
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
RN+++A+ R+I D+ GAY MAD+AHI+GLVA G SP + H VT+TTHKTLRG R G
Sbjct: 179 PRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLRGPRGG 238
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I S D + G + INSA+FPGLQGGP H IA AVA + + E+K
Sbjct: 239 LIL------SNDEEIGHK--------INSALFPGLQGGPLMHIIAAKAVAFLENLQPEYK 284
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
Y QV++N +AL+ +L E GY I+TGG+DNH++LVDLR G G A L+ I CN
Sbjct: 285 SYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRAGITCN 344
Query: 386 KNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425
KN P D S SG+RLGTPA T+RG EKDF V H +
Sbjct: 345 KNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMV 385
>3PGY-A nrPDB
Length = 415
Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 196/430 (45%), Positives = 263/430 (61%), Gaps = 33/430 (7%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ D + I++E RQ +ELIASENF S AV+EA GS L NKY+EGYPG+RYYGG
Sbjct: 7 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 66
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
EF+D E++ RA + + VNVQP+SG AN AVY +E ++G++L
Sbjct: 67 CEFVDVTESIAIDRAKALFGAEH----VNVQPHSGPQANMAVYLVALEMGDTVLGMNLSH 122
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + F+ + Y V+ DT INYD++ + A PKLI+AG S Y
Sbjct: 123 GGHLTHG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAY 177
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
SR +++ + ++IADE A LM DMAHI+GLVAAG+ P+P E+ VTTTTHKTLRG R G
Sbjct: 178 SRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 237
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
MI ++ K I+ +FPG+QGGP H IA AVA +A+ FK
Sbjct: 238 MILCKEEYKKD---------------IDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFK 282
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR-SKGTDGGRAEKVLEACSIAC 384
YQ QVV N + L+EAL G++IV+GG+DNHL+ VD++ S G G AE+ L++ I C
Sbjct: 283 TYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITC 342
Query: 385 NKNTCPGDRSA-LRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKNT P D+ SG+RLGTPA T+RG EK F++VA I L L+ D
Sbjct: 343 NKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKI----ISLALKNSKD---EE 395
Query: 444 TLKEFKERLA 453
L++ KER+A
Sbjct: 396 KLQQAKERVA 405
>3N0L-A nrPDB
Length = 417
Score = 355 bits (911), Expect = 2e-98, Method: Compositional matrix adjust.
Identities = 192/404 (47%), Positives = 259/404 (64%), Gaps = 25/404 (6%)
Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82
A L+ D E++++ KE RQ GLE+IASENF V+E +GS L NKY+EGYPG+RY
Sbjct: 3 AMSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRY 62
Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142
YGG EF+DE+ETL +R + + C NVQP SGS AN VY AL+ P +I+G+D
Sbjct: 63 YGGCEFVDEIETLAIERCKKLF----NCKFANVQPNSGSQANQGVYAALINPGDKILGMD 118
Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202
L GGHLTHG K+S++ +ES Y V D G I+Y+++ E A+ PKLI+ G
Sbjct: 119 LSHGGHLTHG-----AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGA 172
Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262
S Y+R +++A+ R+IADE GAYL AD+AHI+GLV AG PSPF + HVV++TTHKTLRG
Sbjct: 173 SAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGP 232
Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322
R G+I + D + K+ INSA+FPG+QGGP H IA AV K ++
Sbjct: 233 RGGIIM------TNDEELAKK--------INSAIFPGIQGGPLMHVIAAKAVGFKFNLSD 278
Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382
E+KVY QV N + L+ L + +K+V+ G+DNHL+L+ + G A+ L I
Sbjct: 279 EWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGI 338
Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425
NKNT PG+ RS SGLRLGTPALT+RG EK+ + V+++I
Sbjct: 339 TANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYI 382
>3G8M-A nrPDB
Length = 417
Score = 343 bits (879), Expect = 1e-94, Method: Compositional matrix adjust.
Identities = 195/401 (48%), Positives = 261/401 (65%), Gaps = 23/401 (5%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ D D E++ +++E RQ +ELIASEN+ S V++A GS L NK++EGYPG+RYYGG
Sbjct: 8 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKFAEGYPGKRYYGG 67
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D +E L RA + + D NVQP+SGS ANFAVYTAL+EP ++G++L
Sbjct: 68 CEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMNLAH 123
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + + +PY ++ TG+I+Y LE+ A+ PK+II G S Y
Sbjct: 124 GGHLTHG-----SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGFSAY 177
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
S +++A++R+IAD GAYL DMAH++GLVAAGV P+P H HVVTTTTHKTL G R G
Sbjct: 178 SGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 237
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I K G E LY +NSAVFPG QGGP H IAG AVALK+AM EFK
Sbjct: 238 LIL---------AKGGSEELY---KKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEPEFK 285
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
YQ QV N +A+ E E GYK+V+GG+DNHL LVDL K G A+ L +I N
Sbjct: 286 TYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANITVN 345
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425
KN+ P D +S SG+R+GTPA+T RG E + +++A ++
Sbjct: 346 KNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWM 386
>5VMB-A nrPDB
Length = 425
Score = 341 bits (874), Expect = 5e-94, Method: Compositional matrix adjust.
Identities = 186/401 (46%), Positives = 254/401 (63%), Gaps = 23/401 (5%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ + D E+ I E RQ +ELIASEN+ S AV+EA GS L NKY+EGYPG+RYYGG
Sbjct: 15 ISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYGG 74
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
EF+D +E + RA + + D NVQP++GS AN AVY AL+ P ++G+ L
Sbjct: 75 CEFVDVIEQMAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLNPGDTVLGMSLAH 130
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG K+S + + ++ Y +N +TG I+Y+++E A P++I+AG S Y
Sbjct: 131 GGHLTHG-----AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSAY 185
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
SR +++ R R IAD+ GAYL DMAH++GLVAAGV P+P + V TTTTHKTLRG R+G
Sbjct: 186 SRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRSG 245
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I K +EI E + SAVFPG QGGP HAIA A+ K+AM+ +FK
Sbjct: 246 LIL---------AKANEEI----EKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDFK 292
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
YQ QVV N +A++E GY +V+GG+DNHL L+ L + G A+ L A I N
Sbjct: 293 AYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITVN 352
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425
KN+ P D RS SG+R+GTPA+T+RG E + +++A +I
Sbjct: 353 KNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWI 393
>3H7F-A nrPDB
Length = 447
Score = 336 bits (862), Expect = 1e-92, Method: Compositional matrix adjust.
Identities = 198/438 (45%), Positives = 259/438 (59%), Gaps = 35/438 (7%)
Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81
++ PL + D ++ ++ KE RQR LE+IASENF RAVL+A GS L NKY+EG PG+R
Sbjct: 22 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 81
Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141
YYGG E +D +E L + RA + + NVQP+SG+ AN AV AL+ P R++GL
Sbjct: 82 YYGGCEHVDVVENLARDRAKALFGAE----FANVQPHSGAQANAAVLHALMSPGERLLGL 137
Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201
DL +GGHLTHG +++ + +E+ Y V+P T I+ D + A F PK+IIAG
Sbjct: 138 DLANGGHLTHGM-----RLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAG 192
Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261
S Y R L++A R IADE GA L+ DMAH +GLVAAG+ PSP H VV+TT HKTL G
Sbjct: 193 WSAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG 252
Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321
R+G+I GK+ INSAVFPG QGGP H IAG AVALK A T
Sbjct: 253 GRSGLI------------VGKQ---QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAAT 297
Query: 322 LEFKVYQHQVVANCRALSEAL-----TELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKV 376
EF Q + ++ R +++ L + G +V+GG+D HL+LVDLR DG AE +
Sbjct: 298 PEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDL 357
Query: 377 LEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 435
L I N+N P D R + SGLR+GTPAL +RG + +F +VA I L
Sbjct: 358 LHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADI----IATALAT 413
Query: 436 QSDTGVRATLKEFKERLA 453
S V A LK+ RLA
Sbjct: 414 GSSVDVSA-LKDRATRLA 430
>3GBX-A nrPDB
Length = 420
Score = 336 bits (861), Expect = 2e-92, Method: Compositional matrix adjust.
Identities = 188/401 (46%), Positives = 261/401 (65%), Gaps = 23/401 (5%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ D D E++ +++E RQ +ELIASEN+ S V++A GS L NKY+EGYPG+RYYGG
Sbjct: 11 IADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRYYGG 70
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D +E L RA + + D NVQP+SGS ANFAVYTAL++P ++G++L
Sbjct: 71 CEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMNLAQ 126
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + + +PY ++ ++G I+YD++ + A+ PK+II G S Y
Sbjct: 127 GGHLTHG-----SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGFSAY 180
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
S +++A++R+IAD GAYL DMAH++GL+AAGV P+P H HVVTTTTHKTL G R G
Sbjct: 181 SGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGPRGG 240
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I K G E LY +NSAVFP QGGP H IAG AVALK+AM EFK
Sbjct: 241 LIL---------AKGGDEELY---KKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEPEFK 288
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
VYQ QV N +A+ E GYK+V+GG++NHL L+DL K G A+ L +I N
Sbjct: 289 VYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANITVN 348
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFI 425
KN+ P D +S SG+R+G+PA+T RG E + +++A ++
Sbjct: 349 KNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWM 389
>4WXB-A nrPDB
Length = 428
Score = 334 bits (856), Expect = 5e-92, Method: Compositional matrix adjust.
Identities = 182/406 (44%), Positives = 260/406 (64%), Gaps = 25/406 (6%)
Query: 27 KDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGT 86
K D E++N I E+ RQ+ +ELIASEN S+AV+ A G+ L NKY+EGYPG+RYYGGT
Sbjct: 21 KAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRYYGGT 80
Query: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
ID +ETL +RA + + NVQP+SGS AN AVY +L++P +MG+DL G
Sbjct: 81 AVIDVVETLAIERAKKLFG----AKFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAG 136
Query: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
GHLTHG +S + + + Y V+ ++ ++YD + A+ PKLI+AG S YS
Sbjct: 137 GHLTHG-----APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYS 191
Query: 207 RNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGM 266
R +++A+ R+IAD GAYLM DMAHI+GLVA+G PSP + HV TTTTHKTLRG R G+
Sbjct: 192 RIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGL 251
Query: 267 IFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKV 326
I T E ++ +NSAVFPGLQGGP H IA AVALK+A+ FK
Sbjct: 252 IL-----------TDDE---DIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKE 297
Query: 327 YQHQVVANCRALSEALTE-LGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
Y V+ N A+++ + +++++GG++NHL LVD+ +G A+ VLE +I N
Sbjct: 298 YGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLN 357
Query: 386 KNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430
KN+ P ++ S + SG+R+G+PA+TSRG+ E + +++A ++ +E
Sbjct: 358 KNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALE 403
>4P3M-A nrPDB
Length = 429
Score = 332 bits (850), Expect = 3e-91, Method: Compositional matrix adjust.
Identities = 187/429 (43%), Positives = 254/429 (59%), Gaps = 26/429 (6%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ D D E++ I E RQ +ELIASEN+ S V+EA GS L NKY+EGYPG+RYYGG
Sbjct: 8 IADYDPELWQSITDEVQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D E+L +RA + D NVQP+SGS AN AVY AL P I+G+ L
Sbjct: 68 CEYVDVAESLAIERAKSLFGADY----ANVQPHSGSQANAAVYQALCAPGDTILGMSLAH 123
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG +S + + ++ Y + P+TG ++Y ++E A P +IIAG S Y
Sbjct: 124 GGHLTHG-----SHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSAY 178
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
S +++A+ R+IAD+ GAYL DMAH++GLVAAG+ P+P VVTTTTHKTL G R G
Sbjct: 179 SGIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKTLGGPRGG 238
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I + +E +NSAVFPG QGGP H IA AVA K+ EF
Sbjct: 239 LILAKANEA-------------IEKKLNSAVFPGQQGGPLMHVIAAKAVAFKECAEPEFA 285
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
VYQ QV+ N +A+ ++ GYKIV+GG++NHL LVDL ++ G A+ L I N
Sbjct: 286 VYQQQVLDNAKAMVKSFLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALGNAHITVN 345
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KN+ P D RS SGLR+GTPAL RG+ + Q+ A ++ I+ + + T
Sbjct: 346 KNSVPNDPRSPFVTSGLRIGTPALARRGV---NAQQSAELALWMCDVLDAIKDEAKLATT 402
Query: 445 LKEFKERLA 453
+ K ++A
Sbjct: 403 ITAVKVKVA 411
>5VC2-A nrPDB
Length = 424
Score = 330 bits (845), Expect = 1e-90, Method: Compositional matrix adjust.
Identities = 180/432 (41%), Positives = 267/432 (61%), Gaps = 29/432 (6%)
Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81
+A L+ +D E++ +I +E RQ LE+IASEN+ +V+EA+GS L NKY+EGYP +R
Sbjct: 9 MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKR 68
Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141
YYGG E +D++E+L +RA + + C NVQ +SGS AN AVY AL++P+ +I+G+
Sbjct: 69 YYGGCEVVDKIESLAIERAKKLF----NCQFANVQAHSGSQANNAVYHALLKPYDKILGM 124
Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201
DL GGHLTHG K+S T ++S Y VN D GYI+Y++ + A+ P++I+ G
Sbjct: 125 DLSCGGHLTHG-----AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCG 178
Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261
S Y R +++ + R+IADE GA L+ D+AH++GLV PF HCHVV++TTHKTLRG
Sbjct: 179 FSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRG 238
Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321
R G+I T E + + I+ A+FPG QGGP H IA AV K+ +
Sbjct: 239 PRGGIIL-----------TNDE---EIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLK 284
Query: 322 LEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACS 381
EFK Y V +N + L++AL E +K+V+GG+ NHL+L+D K G A+ L
Sbjct: 285 PEFKAYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAG 344
Query: 382 IACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQ----KVAHFIHRGIELTLQIQ 436
I NKNT PG+ RS SG+R+G+ AL++RG+ K+F+ K++ ++ ++LQ+
Sbjct: 345 ITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLH 404
Query: 437 SDTGVRATLKEF 448
++A +F
Sbjct: 405 VKEELKAMANQF 416
>4OTL-A nrPDB
Length = 423
Score = 327 bits (839), Expect = 5e-90, Method: Compositional matrix adjust.
Identities = 185/428 (43%), Positives = 256/428 (59%), Gaps = 26/428 (6%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ + D E++ I++E+ RQ +ELIASEN+ S AV+ A GS L NKY+EGYPG+RYYGG
Sbjct: 17 IANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 76
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D +E L R Q + + NVQP SGS AN V+ A+++P IMG+ L
Sbjct: 77 CEYVDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 132
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + +F + Y +N + I+YD E+ A PKLI+AG S +
Sbjct: 133 GGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYDAAEKLANEHKPKLIVAGASAF 186
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
+ +++ RL KIA GAYLM DMAH +GL+AAGV P+P H VTTTTHK+LRG R G
Sbjct: 187 ALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 246
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I + E INSA+FPG+QGGP H IA AVA K+A++ EFK
Sbjct: 247 VILMKA---------------EYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFK 291
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
YQ +VV N R L+E L + G +IV+G +++H++LVDLR+K G AE L A I N
Sbjct: 292 EYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVN 351
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KN P D SG+RLG+PA+T+RG + ++V + I +E + VRA
Sbjct: 352 KNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQ 411
Query: 445 LKEFKERL 452
+ E +R
Sbjct: 412 VAELTKRF 419
>4BHD-A nrPDB
Length = 428
Score = 202 bits (514), Expect = 3e-52, Method: Compositional matrix adjust.
Identities = 143/436 (32%), Positives = 224/436 (51%), Gaps = 41/436 (9%)
Query: 33 VYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDEL 92
+ ++ K+ R ++LIASEN S AV EA + ++Y+EG PG+R Y G ++IDE+
Sbjct: 9 IRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGCKYIDEV 68
Query: 93 ETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHG 152
ETLC + + + +K + NVQP SG AN AV+ A +P ++M L +PDGGH++H
Sbjct: 69 ETLCIELSKELFKAE----HANVQPTSGVVANLAVFFAETKPGDKLMALSVPDGGHISHW 124
Query: 153 FMTDKKKISATSIF-FESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEY 211
K+SA I + + + +P+ I+ D + + PKLI+ G S +
Sbjct: 125 ------KVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLFPFPHPV 178
Query: 212 ARLRKIADENGAYLMADMAHISGLVAAGVVPSPF-EHCHVVTTTTHKTLRGCRAGMIFYR 270
A + A E GA + D AH+ GL+A P E + +THKT G + G+I
Sbjct: 179 ADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQGGVILTT 238
Query: 271 KGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF-KVYQH 329
K ++ D I+S VFPG+ H H AG+A+AL A LEF + Y
Sbjct: 239 K--ENADK-------------IDSHVFPGVVSNHHLHHKAGLAIAL--AEMLEFGEAYAK 281
Query: 330 QVVANCRALSEALTELGYKIVTGGSD---NHLILVDLRSKGT---DGGRAEKVLEACSIA 383
QV+ N +AL++AL E G+ ++ D +H +++D+ S K+ E +I
Sbjct: 282 QVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMYEEANII 341
Query: 384 CNKNTCPGD--RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441
NKN P D ++ PSG+RLGT T G+ EK+ +++A F+ R + + + V
Sbjct: 342 LNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKR---IAIDKEKPEKV 398
Query: 442 RATLKEFKERLAGDKY 457
R +KEF + + Y
Sbjct: 399 REDVKEFAKEYSTIHY 414
>5HSI-A nrPDB
Length = 634
Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust.
Identities = 46/189 (24%), Positives = 77/189 (40%), Gaps = 15/189 (7%)
Query: 59 RAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPY 118
+ VL+ L + + + RY+G ETL AL AY W N Y
Sbjct: 72 KTVLDQLSERIRTESVPWHSAGRYWGHMNS----ETLMP--ALLAYNY-AMLWNGNNVAY 124
Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKIS-ATSIFFESMPY---KV 174
SPA + + + R+MG D G + G + + + + A +I +S+P+ +V
Sbjct: 125 ESSPATSQMEEEVGQEFARLMGYDYGWGHIVADGSLANLEGLWYARNI--KSLPFAMKEV 182
Query: 175 NPD--TGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHI 232
NP+ G +++ L + L AG+ AR K G +L+ H
Sbjct: 183 NPELVAGKSDWELLNMPTKEIMDLLENAGSQIDEVKKRSARSGKNLQRLGKWLVPQTKHY 242
Query: 233 SGLVAAGVV 241
S + AA ++
Sbjct: 243 SWMKAADII 251
>3H9N-A nrPDB
Length = 177
Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 16/51 (31%), Positives = 28/51 (54%), Gaps = 1/51 (1%)
Query: 273 VKSVDPKTGKEILYNLESLINSAVFPGLQGGPHN-HAIAGVAVALKQAMTL 322
+K VD + +IL N+E ++ +VFP L+ G + H + G V + T+
Sbjct: 63 LKGVDDREAAQILANVEIGVDLSVFPELEEGDYYWHDLIGCTVVNLEGYTM 113
>3VKQ-A nrPDB
Length = 591
Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust.
Identities = 27/99 (27%), Positives = 43/99 (43%), Gaps = 7/99 (7%)
Query: 280 TGKEILYNLESLINSAVFPGLQGGPH--NHAIAGVAVALK--QAMTLEFKVYQHQVVANC 335
G LY + + A P + G N + G A + +A+ L+ V VV C
Sbjct: 259 VGSHDLYEHPHINDLAYMPATKDGRFGFNLLVGGFFSAKRCDEAIPLDAWVPADDVVPVC 318
Query: 336 RALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374
RA+ EA +LG++ G ++ + G +G RAE
Sbjct: 319 RAILEAFRDLGFR---GNRQKCRMMWLIDELGVEGFRAE 354
>3T2C-A nrPDB
Length = 407
Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust.
Identities = 19/47 (40%), Positives = 25/47 (53%), Gaps = 5/47 (10%)
Query: 233 SGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPK 279
SGL A G V F H H+V H +RG AG + + + SVDP+
Sbjct: 243 SGLPAVGEVLEAFAHPHLV----HGWMRGSHAGPLMPARFI-SVDPE 284
>2RAG-A nrPDB
Length = 417
Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust.
Identities = 16/40 (40%), Positives = 21/40 (52%), Gaps = 6/40 (15%)
Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSP 244
+ RNL+ ARL+KIAD GA I+ + PSP
Sbjct: 259 HPRNLDDARLKKIADAGGAIC------INSIYLTDTTPSP 292
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
1BJ4-A nrPDB 789 0.0
1RVY-A nrPDB 769 0.0
1EJI-A nrPDB 749 0.0
5X3V-A nrPDB 702 0.0
5Z0Y-A nrPDB 683 0.0
6CCZ-A nrPDB 665 0.0
5XMU-A nrPDB 625 e-179
4O6Z-A nrPDB 621 e-178
4P3M-A nrPDB 612 e-175
2DKJ-A nrPDB 610 e-175
1YJS-A nrPDB 607 e-174
5VMB-A nrPDB 606 e-174
4J5U-A nrPDB 603 e-173
3N0L-A nrPDB 601 e-172
3G8M-A nrPDB 598 e-171
3GBX-A nrPDB 598 e-171
3PGY-A nrPDB 597 e-171
3ECD-A nrPDB 591 e-169
4OTL-A nrPDB 586 e-168
5VC2-A nrPDB 580 e-166
4WXB-A nrPDB 564 e-161
3H7F-A nrPDB 561 e-160
4BHD-A nrPDB 471 e-133
Sequences not found previously or not previously below threshold:
3TQX-A nrPDB 54 2e-07
1M6S-A nrPDB 44 1e-04
3WY7-A nrPDB 43 3e-04
1CS1-A nrPDB 43 4e-04
4BMK-A nrPDB 40 0.002
2X8U-A nrPDB 40 0.002
3A2B-A nrPDB 39 0.005
2AEV-A nrPDB 39 0.005
2BWN-A nrPDB 38 0.008
3NNK-A nrPDB 38 0.008
1FC4-A nrPDB 37 0.014
3OP7-A nrPDB 37 0.016
4AOA-A nrPDB 36 0.045
1PQU-A nrPDB 34 0.11
3BB8-A nrPDB 34 0.14
6ONN-A nrPDB 34 0.16
5JAY-A nrPDB 33 0.23
6NPB-A nrPDB 33 0.23
3TRI-A nrPDB 33 0.26
3WPR-A nrPDB 33 0.28
5K1R-A nrPDB 33 0.29
5XT5-A nrPDB 33 0.31
5JWG-A nrPDB 33 0.39
3WGB-A nrPDB 33 0.39
6G21-A nrPDB 32 0.42
2OKJ-A nrPDB 32 0.49
5HH9-A nrPDB 32 0.60
3Q8X-B nrPDB 32 0.69
5TXT-B nrPDB 32 0.70
3WPA-A nrPDB 32 0.70
1XI9-A nrPDB 32 0.77
1GC4-A nrPDB 32 0.80
2OGE-A nrPDB 30 1.7
5W70-A nrPDB 30 1.8
1RVG-A nrPDB 30 1.9
5OFO-C nrPDB 30 2.1
4CIU-A nrPDB 30 2.1
1JBK-A nrPDB 30 2.3
5O5C-A nrPDB 30 2.8
2YWH-A nrPDB 30 2.8
6C9E-A nrPDB 30 2.9
2FJK-A nrPDB 29 4.6
5X8P-8 nrPDB 28 9.0
>1BJ4-A nrPDB
Length = 470
Score = 789 bits (2037), Expect = 0.0, Method: Composition-based stats.
Identities = 467/470 (99%), Positives = 467/470 (99%)
Query: 11 DADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 70
DADLWSSHD MLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN
Sbjct: 1 DADLWSSHDAMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLN 60
Query: 71 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 130
NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA
Sbjct: 61 NKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTA 120
Query: 131 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 190
LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA
Sbjct: 121 LVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENA 180
Query: 191 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 250
RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV
Sbjct: 181 RLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHV 240
Query: 251 VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIA 310
VTTTTHKTLRGCRAGMIFYRKGVKSVDP TGKEILYNLESLINSAVFPGLQGGPHNHAIA
Sbjct: 241 VTTTTHKTLRGCRAGMIFYRKGVKSVDPATGKEILYNLESLINSAVFPGLQGGPHNHAIA 300
Query: 311 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 370
GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG
Sbjct: 301 GVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDG 360
Query: 371 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430
GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE
Sbjct: 361 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 420
Query: 431 LTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 480
LTLQIQSDTGV ATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL
Sbjct: 421 LTLQIQSDTGVAATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPGL 470
>1RVY-A nrPDB
Length = 483
Score = 769 bits (1986), Expect = 0.0, Method: Composition-based stats.
Identities = 445/480 (92%), Positives = 462/480 (96%), Gaps = 1/480 (0%)
Query: 5 VNGAHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEA 64
VNGA +DA LWSSH++MLAQPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEA
Sbjct: 4 VNGAPRDAALWSSHEQMLAQPLKDSDAEVYDIIKKESNRQRVGLELIASENFASRAVLEA 63
Query: 65 LGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPAN 124
LGSCLNNKYS+GYPGQRYYGGTE IDELETLCQKRALQAY LDPQCWGVNVQPYSGSPAN
Sbjct: 64 LGSCLNNKYSQGYPGQRYYGGTEHIDELETLCQKRALQAYGLDPQCWGVNVQPYSGSPAN 123
Query: 125 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYD 184
FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESM YKVNPDTGYI+YD
Sbjct: 124 FAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMAYKVNPDTGYIDYD 183
Query: 185 QLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSP 244
+LEENARLFHPKLIIAGTSCYSRNL+Y RLRKIADENGAYLMADMAHISGLV AGVVPSP
Sbjct: 184 RLEENARLFHPKLIIAGTSCYSRNLDYGRLRKIADENGAYLMADMAHISGLVVAGVVPSP 243
Query: 245 FEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGP 304
FEHCHVVTTTTHKTLRGCRAGMIFYR+GV+SVDPKTGKEILYNLESLINSAVFPGLQGGP
Sbjct: 244 FEHCHVVTTTTHKTLRGCRAGMIFYRRGVRSVDPKTGKEILYNLESLINSAVFPGLQGGP 303
Query: 305 HNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR 364
HNHAIAGVAVALKQAMT EFK YQ QVVANCRALS AL ELGYKIVTGGSDNHLILVDLR
Sbjct: 304 HNHAIAGVAVALKQAMTPEFKEYQRQVVANCRALSAALVELGYKIVTGGSDNHLILVDLR 363
Query: 365 SKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 424
SKGTDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLEKDFQKVAHF
Sbjct: 364 SKGTDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 423
Query: 425 IHRGIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483
IHRGIELT+QIQ DTG RATLKEFKE+LAGD K+Q AV+ALR+EVESFA+LFPLPGLP F
Sbjct: 424 IHRGIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAVRALRQEVESFAALFPLPGLPGF 483
>1EJI-A nrPDB
Length = 478
Score = 749 bits (1935), Expect = 0.0, Method: Composition-based stats.
Identities = 435/477 (91%), Positives = 454/477 (95%), Gaps = 1/477 (0%)
Query: 8 AHKDADLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGS 67
A +DA LW+SH+KML+QPLKDSD EVY+IIKKESNRQRVGLELIASENFASRAVLEALGS
Sbjct: 2 ADRDATLWASHEKMLSQPLKDSDAEVYSIIKKESNRQRVGLELIASENFASRAVLEALGS 61
Query: 68 CLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAV 127
LNNKYSEGYPGQRYYGGTEFIDELE LCQKRALQAY LDPQCWGVNVQPYSGSPANFAV
Sbjct: 62 SLNNKYSEGYPGQRYYGGTEFIDELEMLCQKRALQAYHLDPQCWGVNVQPYSGSPANFAV 121
Query: 128 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLE 187
YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKV P+TGYINYDQLE
Sbjct: 122 YTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVYPETGYINYDQLE 181
Query: 188 ENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEH 247
ENA LFHPKLIIAGTSCYSRNL+YARLRKIAD+NGAYLMADMAHISGLVAAGVVPSPFEH
Sbjct: 182 ENASLFHPKLIIAGTSCYSRNLDYARLRKIADDNGAYLMADMAHISGLVAAGVVPSPFEH 241
Query: 248 CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNH 307
CHVVTTTTHKTLRGCRAGMIFYRKGV+SVDPKTGKE Y LESLINSAVFPGLQGGPHNH
Sbjct: 242 CHVVTTTTHKTLRGCRAGMIFYRKGVRSVDPKTGKETYYELESLINSAVFPGLQGGPHNH 301
Query: 308 AIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKG 367
AIAGVAVALKQAMT EFK+YQ QV+ANCRALS+ALTELGYKIVTGGSDNHLIL+DLRSKG
Sbjct: 302 AIAGVAVALKQAMTTEFKIYQLQVLANCRALSDALTELGYKIVTGGSDNHLILMDLRSKG 361
Query: 368 TDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHR 427
TDGGRAEKVLEACSIACNKNTCPGD+SALRPSGLRLGTPALTSRGLLE+DFQKVAHFIHR
Sbjct: 362 TDGGRAEKVLEACSIACNKNTCPGDKSALRPSGLRLGTPALTSRGLLEEDFQKVAHFIHR 421
Query: 428 GIELTLQIQSDTGVRATLKEFKERLAGD-KYQAAVQALREEVESFASLFPLPGLPDF 483
GIELTLQIQS +ATLKEFKE+LAGD K Q+AV LREEVE+FAS F LPGLPDF
Sbjct: 422 GIELTLQIQSHMATKATLKEFKEKLAGDEKIQSAVATLREEVENFASNFSLPGLPDF 478
>5X3V-A nrPDB
Length = 496
Score = 702 bits (1813), Expect = 0.0, Method: Composition-based stats.
Identities = 302/458 (65%), Positives = 365/458 (79%), Gaps = 4/458 (0%)
Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83
+ L DSD E++ ++++E +RQ GLELIASENF SRA LEALGSCLNN+YSEGYPG+RYY
Sbjct: 26 ESLSDSDPEMWELLQREKDRQCRGLELIASENFCSRAALEALGSCLNNRYSEGYPGKRYY 85
Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143
GG E +DE+E LCQ+RAL+A+ LDP WGVNVQPYSGSPAN AVYTAL++PH RIMGLDL
Sbjct: 86 GGAEVVDEIELLCQRRALEAFDLDPAQWGVNVQPYSGSPANLAVYTALLQPHDRIMGLDL 145
Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203
PDGGHLTHG+M+D K+ISATSIFFESMPYK+NP TG I+Y+QL ARLF P+LIIAGTS
Sbjct: 146 PDGGHLTHGYMSDVKRISATSIFFESMPYKLNPKTGLIDYNQLALTARLFRPRLIIAGTS 205
Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Y+R ++YAR+R++ DE A+L+ADMAHISGLVAA V+PSPF+H +VTTTTHKTLRG R
Sbjct: 206 AYARLIDYARMREVCDEVKAHLLADMAHISGLVAAKVIPSPFKHADIVTTTTHKTLRGAR 265
Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
+G+IFYRKGVK+VDPKTG+EI Y E IN AVFP LQGGPHNHAIA VAVALKQA T
Sbjct: 266 SGLIFYRKGVKAVDPKTGREIPYTFEDRINFAVFPSLQGGPHNHAIAAVAVALKQACTPM 325
Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
F+ Y QV+ N RA+++AL E GY +V+GG+DNHL+LVDLR KG DG RAE+VLE SI
Sbjct: 326 FREYSLQVLKNARAMADALLERGYSLVSGGTDNHLVLVDLRPKGLDGARAERVLELVSIT 385
Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKNTCPGDRSA+ P GLRLG PALTSR E DF++V FI G+ + L+++S T A
Sbjct: 386 ANKNTCPGDRSAITPGGLRLGAPALTSRQFREDDFRRVVDFIDEGVNIGLEVKSKT---A 442
Query: 444 TLKEFKERLAGDKYQAA-VQALREEVESFASLFPLPGL 480
L++FK L D + + LR+ VE FA FP+PG
Sbjct: 443 KLQDFKSFLLKDSETSQRLANLRQRVEQFARAFPMPGF 480
>5Z0Y-A nrPDB
Length = 470
Score = 683 bits (1762), Expect = 0.0, Method: Composition-based stats.
Identities = 260/466 (55%), Positives = 346/466 (74%), Gaps = 3/466 (0%)
Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNK 72
L H +M+ L ++D EV IIK E +RQ+ + LIASENF S +V +ALG+ + NK
Sbjct: 5 ALSPEHKQMVEGHLAETDPEVNQIIKDEVDRQKHSIVLIASENFTSTSVFDALGTPMCNK 64
Query: 73 YSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALV 132
YSEGYPG RYYGG E ID +E LCQ+RAL+A+ LD WGVNVQ SGSPAN VY A++
Sbjct: 65 YSEGYPGARYYGGNEHIDRMEILCQQRALKAFHLDGSRWGVNVQTLSGSPANLQVYQAIM 124
Query: 133 EPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARL 192
+PH R+MGLDLP GGHL+HG+ TD +KISA S +FE+MPY+V+ +TG I+YD LE+ A L
Sbjct: 125 KPHDRLMGLDLPHGGHLSHGYQTDTRKISAVSTYFETMPYRVDLETGIIDYDMLEKTAVL 184
Query: 193 FHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVT 252
+ PK+++AGTS Y R ++Y R+R+IAD+ GAYL+ DMAHISGL+AAGV+PSPFE+ +VT
Sbjct: 185 YRPKVLVAGTSAYCRLIDYKRMREIADKVGAYLVVDMAHISGLIAAGVIPSPFEYADIVT 244
Query: 253 TTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGV 312
TTTHK+LRG R MIF+RKGV+SV+PKTGKEI Y+LE+ IN +VFPG QGGPHNH IA +
Sbjct: 245 TTTHKSLRGPRGAMIFFRKGVRSVNPKTGKEIYYDLENPINFSVFPGHQGGPHNHTIAAL 304
Query: 313 AVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGR 372
A ALKQA T EFK YQ QV+ N +AL LGYK+V+ G+D+H++LV L+ K DG R
Sbjct: 305 ATALKQAATPEFKQYQEQVLKNAKALENEFKRLGYKLVSDGTDSHMVLVSLKDKDIDGAR 364
Query: 373 AEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELT 432
E V E +IA NKN+ PGDRSAL P G+R+G PA+T+RG E+DF K+A++I + ++
Sbjct: 365 IETVCENINIALNKNSIPGDRSALVPGGVRIGAPAMTTRGASEEDFVKIANYIDKSVQYA 424
Query: 433 LQIQSDTGVRAT-LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477
++QS+ + A LK+FK ++A + + L+ E+ ++A FPL
Sbjct: 425 KKVQSELPIEANKLKDFKAKIAEGSDE--ITQLKNEISAWAGEFPL 468
>6CCZ-A nrPDB
Length = 455
Score = 665 bits (1715), Expect = 0.0, Method: Composition-based stats.
Identities = 274/467 (58%), Positives = 344/467 (73%), Gaps = 18/467 (3%)
Query: 19 DKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYP 78
+ L L ++D +V+ II KE +RQ LELIASENF S+AV+EA+GSCL NKYSEG P
Sbjct: 2 NAFLDYGLSEADPDVHAIINKEKDRQFRSLELIASENFTSKAVMEAVGSCLTNKYSEGLP 61
Query: 79 GQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRI 138
G+RYYGG E IDELE LCQ+RAL A+ LD WGVNVQP SGSPANFAVYTA+++PH RI
Sbjct: 62 GKRYYGGNEHIDELEILCQQRALAAFHLDGDKWGVNVQPLSGSPANFAVYTAILKPHDRI 121
Query: 139 MGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLI 198
MGLDLP GGHL+HGFMT K+++S TSI+FESMPY+++ TG I+YD LE+ A LF PKLI
Sbjct: 122 MGLDLPHGGHLSHGFMTAKRRVSGTSIYFESMPYRLDESTGVIDYDMLEKTAALFRPKLI 181
Query: 199 IAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKT 258
IAG S Y R+++YAR RKIAD GA+LM DMAH+SGL+AA V+ PFE +VTTTTHK+
Sbjct: 182 IAGASAYPRDIDYARFRKIADSVGAFLMMDMAHVSGLIAASVLADPFEFVDIVTTTTHKS 241
Query: 259 LRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQ 318
LRG R GMIF++K +LES IN+AVFPGLQGGPHNH I G+AV LK
Sbjct: 242 LRGPRGGMIFFKKDAV---------HGVDLESAINNAVFPGLQGGPHNHTIGGLAVCLKY 292
Query: 319 AMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLE 378
A + +FK YQ+QVVANCRAL+ L E YK+V+GGSDNHL+LVDLR G DG R EK+L+
Sbjct: 293 AQSPDFKNYQNQVVANCRALANRLVEHEYKLVSGGSDNHLVLVDLRPSGIDGARVEKILD 352
Query: 379 ACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQ-- 436
SI NKN+ PGD+SAL P G+R+G+PA+T+RGL EK+F+ +A IH G+ ++L+ +
Sbjct: 353 MASITLNKNSVPGDKSALVPGGIRIGSPAMTTRGLGEKEFELIADLIHEGVRISLEAKSL 412
Query: 437 -SDTGVRATLKEF--KERLAGDKYQAAVQALREEVESFASLFPLPGL 480
S T V+ L E GDK V LR +VE+ A+ +P+PG+
Sbjct: 413 VSGTKVQDFLNFVLAPEFPLGDK----VSNLRRKVEALATQYPIPGV 455
>5XMU-A nrPDB
Length = 442
Score = 625 bits (1611), Expect = e-179, Method: Composition-based stats.
Identities = 214/455 (47%), Positives = 294/455 (64%), Gaps = 17/455 (3%)
Query: 24 QPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYY 83
+PL+ D E+++I+ E RQR + LIASEN + AV E LG+ ++NKYSEGYP +RYY
Sbjct: 5 EPLEQIDKELHDILADEEKRQRETINLIASENLTNGAVRECLGNRVSNKYSEGYPKKRYY 64
Query: 84 GGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDL 143
GG +FID++E LCQKRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L
Sbjct: 65 GGNDFIDKIEELCQKRALEAFNVSDEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHL 124
Query: 144 PDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTS 203
GGHLTHGF +KKK+S TS FES YK N GY++ D + E A F PK+II G +
Sbjct: 125 CSGGHLTHGFFDEKKKVSITSDMFESKLYKCN-SQGYVDLDAVREMALSFKPKVIICGYT 183
Query: 204 CYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCR 263
Y R+++Y + R+I DE AYL AD++HIS VA ++ +PF H VVTTTTHK LRG R
Sbjct: 184 SYPRDIDYQQFRQICDEVNAYLFADISHISSFVACNILNNPFLHADVVTTTTHKILRGPR 243
Query: 264 AGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLE 323
+ +IF+ K+ +E INSAVFP QGGPHN+ IA VA LK+ +
Sbjct: 244 SALIFFN-----------KKRNPGIEQKINSAVFPSFQGGPHNNKIAAVACQLKEVHSPA 292
Query: 324 FKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIA 383
FK Y QV+ N +AL++AL +VT G+DNHLI+VDLR G + ++ A +++
Sbjct: 293 FKEYTQQVLLNSKALAKALISKQIDLVTNGTDNHLIVVDLRKFSITGSKLQETCNAINVS 352
Query: 384 CNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKNT P D + PSG+R+GTPA+T+RG EKD + +A + R I++T+ +Q G +
Sbjct: 353 LNKNTIPSDVDCVSPSGVRIGTPAMTTRGAKEKDMEFIADVLARAIKITVDLQEQYGKK- 411
Query: 444 TLKEFKERLAGDKYQAAVQALREEVESFASLFPLP 478
L +FK+ L G+ A +Q L++EV ++A P P
Sbjct: 412 -LVDFKKGLPGN---AQLQQLKQEVVTWAGALPFP 442
>4O6Z-A nrPDB
Length = 480
Score = 621 bits (1602), Expect = e-178, Method: Composition-based stats.
Identities = 207/453 (45%), Positives = 287/453 (63%), Gaps = 17/453 (3%)
Query: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
PL+ D E++++++KE NRQ + LIASEN + AV E LG ++NKYSEGYP +RYYG
Sbjct: 44 PLQKYDKELFDLLEKEKNRQIETINLIASENLTNTAVRECLGDRISNKYSEGYPHKRYYG 103
Query: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144
G +++D++E LC KRAL+A+ + + WGVNVQP SGS AN ALV G+IMG+ L
Sbjct: 104 GNDYVDKIEELCYKRALEAFNVSEEEWGVNVQPLSGSAANVQALYALVGVKGKIMGMHLC 163
Query: 145 DGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSC 204
GGHLTHGF +KKK+S TS FES YK N + GY++ + + A F PK+II G +
Sbjct: 164 SGGHLTHGFFDEKKKVSITSDLFESKLYKCNSE-GYVDMESVRNLALSFQPKVIICGYTS 222
Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 264
Y R+++Y R+I DE AYL AD++HIS VA ++ +PF + VVTTTTHK LRG R+
Sbjct: 223 YPRDIDYKGFREICDEVNAYLFADISHISSFVACNLLNNPFTYADVVTTTTHKILRGPRS 282
Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324
+IF+ K+ ++ INS+VFP QGGPHN+ IA VA LK+ T EF
Sbjct: 283 ALIFFN-----------KKRNPGIDQKINSSVFPSFQGGPHNNKIAAVACQLKEVNTPEF 331
Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384
K Y QV+ N +AL+E L + +VT G+DNHLI+VDLR G + ++ A +IA
Sbjct: 332 KEYTKQVLLNSKALAECLLKRNLDLVTNGTDNHLIVVDLRKYNITGSKLQETCNAINIAL 391
Query: 385 NKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
NKNT P D + PSG+R+GTPALT+RG EKD + +A + + I LT ++Q G +
Sbjct: 392 NKNTIPSDVDCVSPSGIRIGTPALTTRGCKEKDMEFIADMLLKAILLTDELQQKYGKK-- 449
Query: 445 LKEFKERLAGDKYQAAVQALREEVESFASLFPL 477
L +FK+ L + + L++EV +A P
Sbjct: 450 LVDFKKGLVNN---PKIDELKKEVVQWAKNLPF 479
>4P3M-A nrPDB
Length = 429
Score = 612 bits (1578), Expect = e-175, Method: Composition-based stats.
Identities = 189/441 (42%), Positives = 256/441 (58%), Gaps = 26/441 (5%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ D D E++ I E RQ +ELIASEN+ S V+EA GS L NKY+EGYPG+RYYGG
Sbjct: 8 IADYDPELWQSITDEVQRQEDHIELIASENYTSPRVMEAQGSQLTNKYAEGYPGKRYYGG 67
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D E+L +RA + D NVQP+SGS AN AVY AL P I+G+ L
Sbjct: 68 CEYVDVAESLAIERAKSLFGADY----ANVQPHSGSQANAAVYQALCAPGDTILGMSLAH 123
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG +S + + ++ Y + P+TG ++Y ++E A P +IIAG S Y
Sbjct: 124 GGHLTHG-----SHVSFSGKMYNAVQYGITPETGILDYAEIERLAVEHKPTMIIAGFSAY 178
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
S +++A+ R+IAD+ GAYL DMAH++GLVAAG+ P+P VVTTTTHKTL G R G
Sbjct: 179 SGIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPVPFADVVTTTTHKTLGGPRGG 238
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I + +E +NSAVFPG QGGP H IA AVA K+ EF
Sbjct: 239 LILAKANEA-------------IEKKLNSAVFPGQQGGPLMHVIAAKAVAFKECAEPEFA 285
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
VYQ QV+ N +A+ ++ GYKIV+GG++NHL LVDL ++ G A+ L I N
Sbjct: 286 VYQQQVLDNAKAMVKSFLARGYKIVSGGTENHLFLVDLIAQDITGKEADAALGNAHITVN 345
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KN+ P D RS SGLR+GTPAL RG+ + Q+ A ++ I+ + + T
Sbjct: 346 KNSVPNDPRSPFVTSGLRIGTPALARRGV---NAQQSAELALWMCDVLDAIKDEAKLATT 402
Query: 445 LKEFKERLAGDKYQAAVQALR 465
+ K ++A V L
Sbjct: 403 ITAVKVKVAALCKACPVYGLE 423
>2DKJ-A nrPDB
Length = 407
Score = 610 bits (1574), Expect = e-175, Method: Composition-based stats.
Identities = 205/452 (45%), Positives = 265/452 (58%), Gaps = 51/452 (11%)
Query: 28 DSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGTE 87
D ++ +I E RQR GLELIASENF S+ V EA+GS L NKY+EGYPG RYYGG E
Sbjct: 6 KRDEALFELIALEEKRQREGLELIASENFVSKQVREAVGSVLTNKYAEGYPGARYYGGCE 65
Query: 88 FIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGG 147
ID +E+L +RA + W NVQP+SGS AN AVY AL+EP +MG+DL GG
Sbjct: 66 VIDRVESLAIERAKALFGA---AW-ANVQPHSGSQANMAVYMALMEPGDTLMGMDLAAGG 121
Query: 148 HLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSR 207
HLTHG +++ + ++ + Y V PDT I+ +++ A PK+I+AG S Y R
Sbjct: 122 HLTHG-----SRVNFSGKLYKVVSYGVRPDTELIDLEEVRRLALEHRPKVIVAGASAYPR 176
Query: 208 NLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMI 267
++ R+IADE GAYL+ DMAH +GLVAAG+ P+P + HVVT+TTHKTLRG R G+I
Sbjct: 177 FWDFKAFREIADEVGAYLVVDMAHFAGLVAAGLHPNPLPYAHVVTSTTHKTLRGPRGGLI 236
Query: 268 FYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVY 327
S DP+ GK I+ +FPG+QGGP H IAG AVA +A+ EFK Y
Sbjct: 237 L------SNDPELGK--------RIDKLIFPGIQGGPLEHVIAGKAVAFFEALQPEFKEY 282
Query: 328 QHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKN 387
VV N + L+E L GY+IVTGG+DNHL LVDLR KG G AE+ L+A I NKN
Sbjct: 283 SRLVVENAKRLAEELARRGYRIVTGGTDNHLFLVDLRPKGLTGKEAEERLDAVGITVNKN 342
Query: 388 TCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRATLK 446
P D + SG+R+GTPA+T+RG ++ VA I R +
Sbjct: 343 AIPFDPKPPRVTSGIRIGTPAITTRGFTPEEMPLVAELIDRAL----------------- 385
Query: 447 EFKERLAGDKYQAAVQALREEVESFASLFPLP 478
+ +ALREEV A P+P
Sbjct: 386 ----------LEGPSEALREEVRRLALAHPMP 407
>1YJS-A nrPDB
Length = 419
Score = 607 bits (1566), Expect = e-174, Method: Composition-based stats.
Identities = 192/439 (43%), Positives = 269/439 (61%), Gaps = 32/439 (7%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
L D +V+ I++E RQ +ELIASENF SRAV+EA GS L NKY+EGYPG+RYYGG
Sbjct: 4 LPQQDPQVFAAIEQERKRQHAKIELIASENFVSRAVMEAQGSVLTNKYAEGYPGRRYYGG 63
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D +E L ++RA Q + + NVQP+SG+ AN AVY ++E ++G++L
Sbjct: 64 CEYVDIVEELARERAKQLFGAE----HANVQPHSGAQANMAVYFTVLEHGDTVLGMNLSH 119
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + + + + Y V+P+T I+YD + E ARL PKLI+A S Y
Sbjct: 120 GGHLTHG-----SPVNFSGVQYNFVAYGVDPETHVIDYDDVREKARLHRPKLIVAAASAY 174
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
R +++A+ R+IADE GAYLM DMAHI+GLVAAG+ P+P + H VTTTTH+TLRG R G
Sbjct: 175 PRIIDFAKFREIADEVGAYLMVDMAHIAGLVAAGLHPNPVPYAHFVTTTTHQTLRGPRGG 234
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
MI ++ I+ A+FPG+QGGP H IA AVA +A+ +FK
Sbjct: 235 MILCQE---------------QFAKQIDKAIFPGIQGGPLMHVIAAKAVAFGEALQDDFK 279
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
Y +VV N + L+ AL G+ +V+GG+DNHL+LVDLR + G AEKVL+ I N
Sbjct: 280 AYAKRVVDNAKRLASALQNEGFTLVSGGTDNHLLLVDLRPQQLTGKTAEKVLDEVGITVN 339
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KNT P D S SG+R+GT A+T+RG ++ ++A I + + G
Sbjct: 340 KNTIPYDPESPFVTSGIRIGTAAVTTRGFGLEEMDEIAAIIGLVL-------KNVGSEQA 392
Query: 445 LKEFKERLAGDKYQAAVQA 463
L+E ++R+A + A
Sbjct: 393 LEEARQRVAALTDPTSRSA 411
>5VMB-A nrPDB
Length = 425
Score = 606 bits (1563), Expect = e-174, Method: Composition-based stats.
Identities = 186/430 (43%), Positives = 261/430 (60%), Gaps = 23/430 (5%)
Query: 25 PLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYG 84
+ + D E+ I E RQ +ELIASEN+ S AV+EA GS L NKY+EGYPG+RYYG
Sbjct: 14 SISEFDPELAQAIASEDERQEAHIELIASENYCSPAVMEAQGSKLTNKYAEGYPGKRYYG 73
Query: 85 GTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLP 144
G EF+D +E + RA + + D NVQP++GS AN AVY AL+ P ++G+ L
Sbjct: 74 GCEFVDVIEQMAIDRAKELFGADY----ANVQPHAGSQANSAVYLALLNPGDTVLGMSLA 129
Query: 145 DGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSC 204
GGHLTHG K+S + + ++ Y +N +TG I+Y+++E A P++I+AG S
Sbjct: 130 HGGHLTHG-----AKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALEHKPRMIVAGFSA 184
Query: 205 YSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRA 264
YSR +++ R R IAD+ GAYL DMAH++GLVAAGV P+P + V TTTTHKTLRG R+
Sbjct: 185 YSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQIADVTTTTTHKTLRGPRS 244
Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324
G+I + +E + SAVFPG QGGP HAIA A+ K+AM+ +F
Sbjct: 245 GLILAKANE-------------EIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEAMSDDF 291
Query: 325 KVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384
K YQ QVV N +A++E GY +V+GG+DNHL L+ L + G A+ L A I
Sbjct: 292 KAYQQQVVKNAQAMAEVFIARGYDVVSGGTDNHLFLLSLIKQDVTGKDADAWLGAAHITV 351
Query: 385 NKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKN+ P D RS SG+R+GTPA+T+RG E + +++A +I I+ + V+A
Sbjct: 352 NKNSVPNDPRSPFVTSGIRIGTPAVTTRGFGEAEVRELAGWIADVIDSKGDEKVIADVKA 411
Query: 444 TLKEFKERLA 453
++ +
Sbjct: 412 KVEAVCAKFP 421
>4J5U-A nrPDB
Length = 420
Score = 603 bits (1555), Expect = e-173, Method: Composition-based stats.
Identities = 201/460 (43%), Positives = 267/460 (58%), Gaps = 43/460 (9%)
Query: 21 MLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQ 80
+ L ++D E+ IIK E RQ +ELIASENF S AVLEA G+ L NKY+EGYP +
Sbjct: 3 IFNNNLHETDKEINEIIKHEKLRQSSVIELIASENFVSPAVLEAQGALLTNKYAEGYPSK 62
Query: 81 RYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMG 140
R+Y G E +D+ E L +R + + C NVQP+SGS AN AVY AL++P ++G
Sbjct: 63 RFYNGCEEVDKAENLAIERVKKLF----NCKYANVQPHSGSQANQAVYLALLQPGDTVLG 118
Query: 141 LDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIA 200
+ L GGHLTHG + + +F ++ Y VN +T I+YD++E A L PKL+IA
Sbjct: 119 MSLDSGGHLTHGAAP-----NMSGKWFNAVSYSVNKETYLIDYDEIERLADLHKPKLLIA 173
Query: 201 GTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLR 260
G S Y RN+++A+ R+I D+ GAY MAD+AHI+GLVA G SP + H VT+TTHKTLR
Sbjct: 174 GFSAYPRNIDFAKFREIVDKVGAYFMADIAHIAGLVATGEHQSPIPYAHAVTSTTHKTLR 233
Query: 261 GCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAM 320
G R G+I S D + G INSA+FPGLQGGP H IA AVA + +
Sbjct: 234 GPRGGLIL------SNDEEIGH--------KINSALFPGLQGGPLMHIIAAKAVAFLENL 279
Query: 321 TLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEAC 380
E+K Y QV++N +AL+ +L E GY I+TGG+DNH++LVDLR G G A L+
Sbjct: 280 QPEYKSYIQQVISNAKALASSLQERGYDILTGGTDNHIVLVDLRKDGITGKLAANSLDRA 339
Query: 381 SIACNKNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDT 439
I CNKN P D S SG+RLGTPA T+RG EKDF V H + ++ + ++
Sbjct: 340 GITCNKNAIPFDETSPFITSGIRLGTPACTTRGFKEKDFVLVGHMVADILDGLKNNEDNS 399
Query: 440 GVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPLPG 479
+ Q + EV LFP G
Sbjct: 400 ALE-------------------QQVLNEVTKLIELFPFYG 420
>3N0L-A nrPDB
Length = 417
Score = 601 bits (1550), Expect = e-172, Method: Composition-based stats.
Identities = 193/431 (44%), Positives = 263/431 (61%), Gaps = 25/431 (5%)
Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82
A L+ D E++++ KE RQ GLE+IASENF V+E +GS L NKY+EGYPG+RY
Sbjct: 3 AMSLEMFDKEIFDLTNKELERQCEGLEMIASENFTLPEVMEVMGSILTNKYAEGYPGKRY 62
Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142
YGG EF+DE+ETL +R + + C NVQP SGS AN VY AL+ P +I+G+D
Sbjct: 63 YGGCEFVDEIETLAIERCKKLF----NCKFANVQPNSGSQANQGVYAALINPGDKILGMD 118
Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202
L GGHLTHG K+S++ +ES Y V D G I+Y+++ E A+ PKLI+ G
Sbjct: 119 LSHGGHLTHG-----AKVSSSGKMYESCFYGVELD-GRIDYEKVREIAKKEKPKLIVCGA 172
Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262
S Y+R +++A+ R+IADE GAYL AD+AHI+GLV AG PSPF + HVV++TTHKTLRG
Sbjct: 173 SAYARVIDFAKFREIADEIGAYLFADIAHIAGLVVAGEHPSPFPYAHVVSSTTHKTLRGP 232
Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322
R G+I L INSA+FPG+QGGP H IA AV K ++
Sbjct: 233 RGGIIMTNDE--------------ELAKKINSAIFPGIQGGPLMHVIAAKAVGFKFNLSD 278
Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382
E+KVY QV N + L+ L + +K+V+ G+DNHL+L+ + G A+ L I
Sbjct: 279 EWKVYAKQVRTNAQVLANVLMDRKFKLVSDGTDNHLVLMSFLDREFSGKDADLALGNAGI 338
Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441
NKNT PG+ RS SGLRLGTPALT+RG EK+ + V+++I ++ + +
Sbjct: 339 TANKNTVPGEIRSPFITSGLRLGTPALTARGFKEKEMEIVSNYIADILDDVNNEKLQENI 398
Query: 442 RATLKEFKERL 452
+ LK+
Sbjct: 399 KQELKKLASNF 409
>3G8M-A nrPDB
Length = 417
Score = 598 bits (1543), Expect = e-171, Method: Composition-based stats.
Identities = 193/432 (44%), Positives = 267/432 (61%), Gaps = 23/432 (5%)
Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82
+ D D E++ +++E RQ +ELIASEN+ S V++A GS L NK++EGYPG+RY
Sbjct: 5 EMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKFAEGYPGKRY 64
Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142
YGG E++D +E L RA + + D NVQP+SGS ANFAVYTAL+EP ++G++
Sbjct: 65 YGGCEYVDIVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLEPGDTVLGMN 120
Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202
L GGHLTHG ++ + + +PY ++ TG+I+Y LE+ A+ PK+II G
Sbjct: 121 LAHGGHLTHG-----SPVNFSGKLYNIVPYGIDA-TGHIDYADLEKQAKEHKPKMIIGGF 174
Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262
S YS +++A++R+IAD GAYL DMAH++GLVAAGV P+P H HVVTTTTHKTL G
Sbjct: 175 SAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVPHAHVVTTTTHKTLAGP 234
Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322
R G+I + G + L +NSAVFPG QGGP H IAG AVALK+AM
Sbjct: 235 RGGLILAKGGSE------------ELYKKLNSAVFPGGQGGPLMHVIAGKAVALKEAMEP 282
Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382
EFK YQ QV N +A+ E E GYK+V+GG+DNHL LVDL K G A+ L +I
Sbjct: 283 EFKTYQQQVAKNAKAMVEVFLERGYKVVSGGTDNHLFLVDLVDKNLTGKEADAALGRANI 342
Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441
NKN+ P D +S SG+R+GTPA+T RG E + +++A ++ ++ +
Sbjct: 343 TVNKNSVPNDPKSPFVTSGIRVGTPAITRRGFKEAEAKELAGWMCDVLDSINDEAVIERI 402
Query: 442 RATLKEFKERLA 453
+ + + R
Sbjct: 403 KGKVLDICARYP 414
>3GBX-A nrPDB
Length = 420
Score = 598 bits (1543), Expect = e-171, Method: Composition-based stats.
Identities = 191/432 (44%), Positives = 270/432 (62%), Gaps = 23/432 (5%)
Query: 23 AQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRY 82
+ D D E++ +++E RQ +ELIASEN+ S V++A GS L NKY+EGYPG+RY
Sbjct: 8 EMNIADYDAELWQAMEQEKVRQEEHIELIASENYTSPRVMQAQGSQLTNKYAEGYPGKRY 67
Query: 83 YGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLD 142
YGG E++D +E L RA + + D NVQP+SGS ANFAVYTAL++P ++G++
Sbjct: 68 YGGCEYVDVVEQLAIDRAKELFGADY----ANVQPHSGSQANFAVYTALLQPGDTVLGMN 123
Query: 143 LPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGT 202
L GGHLTHG ++ + + +PY ++ ++G I+YD++ + A+ PK+II G
Sbjct: 124 LAQGGHLTHG-----SPVNFSGKLYNIVPYGID-ESGKIDYDEMAKLAKEHKPKMIIGGF 177
Query: 203 SCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGC 262
S YS +++A++R+IAD GAYL DMAH++GL+AAGV P+P H HVVTTTTHKTL G
Sbjct: 178 SAYSGVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVPHAHVVTTTTHKTLAGP 237
Query: 263 RAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTL 322
R G+I K G E LY +NSAVFP QGGP H IAG AVALK+AM
Sbjct: 238 RGGLIL---------AKGGDEELY---KKLNSAVFPSAQGGPLMHVIAGKAVALKEAMEP 285
Query: 323 EFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSI 382
EFKVYQ QV N +A+ E GYK+V+GG++NHL L+DL K G A+ L +I
Sbjct: 286 EFKVYQQQVAKNAKAMVEVFLNRGYKVVSGGTENHLFLLDLVDKNLTGKEADAALGRANI 345
Query: 383 ACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGV 441
NKN+ P D +S SG+R+G+PA+T RG E + +++A ++ ++ + V
Sbjct: 346 TVNKNSVPNDPKSPFVTSGIRIGSPAVTRRGFKEAEVKELAGWMCDVLDNINDEATIERV 405
Query: 442 RATLKEFKERLA 453
+A + + R
Sbjct: 406 KAKVLDICARFP 417
>3PGY-A nrPDB
Length = 415
Score = 597 bits (1539), Expect = e-171, Method: Composition-based stats.
Identities = 192/440 (43%), Positives = 263/440 (59%), Gaps = 33/440 (7%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ D + I++E RQ +ELIASENF S AV+EA GS L NKY+EGYPG+RYYGG
Sbjct: 7 ITKQDKVIAEAIEREFQRQNSNIELIASENFVSEAVMEAQGSVLTNKYAEGYPGRRYYGG 66
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
EF+D E++ RA + + VNVQP+SG AN AVY +E ++G++L
Sbjct: 67 CEFVDVTESIAIDRAKALFGAE----HVNVQPHSGPQANMAVYLVALEMGDTVLGMNLSH 122
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + F+ + Y V+ DT INYD++ + A PKLI+AG S Y
Sbjct: 123 GGHLTHG-----APVNFSGKFYNFVEYGVDKDTERINYDEVRKLALEHKPKLIVAGASAY 177
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
SR +++ + ++IADE A LM DMAHI+GLVAAG+ P+P E+ VTTTTHKTLRG R G
Sbjct: 178 SRTIDFKKFKEIADEVNAKLMVDMAHIAGLVAAGLHPNPVEYADFVTTTTHKTLRGPRGG 237
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
MI ++ + I+ +FPG+QGGP H IA AVA +A+ FK
Sbjct: 238 MILCKE---------------EYKKDIDKTIFPGIQGGPLEHVIAAKAVAFGEALENNFK 282
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLR-SKGTDGGRAEKVLEACSIAC 384
YQ QVV N + L+EAL G++IV+GG+DNHL+ VD++ S G G AE+ L++ I C
Sbjct: 283 TYQQQVVKNAKVLAEALINEGFRIVSGGTDNHLVAVDVKGSIGLTGKEAEETLDSVGITC 342
Query: 385 NKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRA 443
NKNT P D SG+RLGTPA T+RG EK F++VA I ++ +
Sbjct: 343 NKNTIPFDQEKPFVTSGIRLGTPAATTRGFDEKAFEEVAKIISLALKNSKD-------EE 395
Query: 444 TLKEFKERLAGDKYQAAVQA 463
L++ KER+A + +
Sbjct: 396 KLQQAKERVAKLTAEYPLYQ 415
>3ECD-A nrPDB
Length = 425
Score = 591 bits (1524), Expect = e-169, Method: Composition-based stats.
Identities = 205/464 (44%), Positives = 264/464 (56%), Gaps = 42/464 (9%)
Query: 15 WSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYS 74
S+ + +Q L + D V I KE RQ+ +ELIASEN SRAVL+A GS L NKY+
Sbjct: 2 MSNANPFFSQSLAERDASVRGAILKELERQQSQVELIASENIVSRAVLDAQGSVLTNKYA 61
Query: 75 EGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEP 134
EGYPG+RYYGG EF DE+E L +R + + NVQP+SG+ AN AV AL +P
Sbjct: 62 EGYPGKRYYGGCEFADEVEALAIERVKRLFNA----GHANVQPHSGAQANGAVMLALAKP 117
Query: 135 HGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFH 194
++G+ L GGHLTHG K + + +F ++ Y V+ DT I+YDQ+E A+
Sbjct: 118 GDTVLGMSLDAGGHLTHG-----AKPALSGKWFNALQYGVSRDTMLIDYDQVEALAQQHK 172
Query: 195 PKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTT 254
P LIIAG S Y R L++AR R IAD GA LM DMAHI+G++AAG +P EH HVVT+T
Sbjct: 173 PSLIIAGFSAYPRKLDFARFRAIADSVGAKLMVDMAHIAGVIAAGRHANPVEHAHVVTST 232
Query: 255 THKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAV 314
THKTLRG R G + + INSAVFPGLQGGP H IAG AV
Sbjct: 233 THKTLRGPRGGFVLTNDE--------------EIAKKINSAVFPGLQGGPLMHVIAGKAV 278
Query: 315 ALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAE 374
A +A+T +FK Y +V+AN +AL + L G +VTGG+DNHL+LVDLR KG G + E
Sbjct: 279 AFGEALTDDFKTYIDRVLANAQALGDVLKAGGVDLVTGGTDNHLLLVDLRPKGLKGAQVE 338
Query: 375 KVLEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTL 433
+ LE I CNKN P D SG+RLGTPA T+RG +F++V I E
Sbjct: 339 QALERAGITCNKNGIPFDPEKPTITSGIRLGTPAGTTRGFGAAEFREVGRLILEVFE--- 395
Query: 434 QIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPL 477
+ GD +R E+ + FP+
Sbjct: 396 -------------ALRTNPEGDHATEQR--VRREIFALCERFPI 424
>4OTL-A nrPDB
Length = 423
Score = 586 bits (1511), Expect = e-168, Method: Composition-based stats.
Identities = 185/429 (43%), Positives = 256/429 (59%), Gaps = 26/429 (6%)
Query: 26 LKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGG 85
+ + D E++ I++E+ RQ +ELIASEN+ S AV+ A GS L NKY+EGYPG+RYYGG
Sbjct: 17 IANVDPEIFAAIEQENRRQEDHIELIASENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGG 76
Query: 86 TEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPD 145
E++D +E L R Q + + NVQP SGS AN V+ A+++P IMG+ L
Sbjct: 77 CEYVDVVEQLAIDRVKQLFGAE----AANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAH 132
Query: 146 GGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GGHLTHG ++ + +F + Y +N + I+YD E+ A PKLI+AG S +
Sbjct: 133 GGHLTHG-----SPVNMSGKWFNVVSYGLNENED-IDYDAAEKLANEHKPKLIVAGASAF 186
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAG 265
+ +++ RL KIA GAYLM DMAH +GL+AAGV P+P H VTTTTHK+LRG R G
Sbjct: 187 ALKIDFERLAKIAKSVGAYLMVDMAHYAGLIAAGVYPNPVPHADFVTTTTHKSLRGPRGG 246
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFK 325
+I + E INSA+FPG+QGGP H IA AVA K+A++ EFK
Sbjct: 247 VILMKA---------------EYEKPINSAIFPGIQGGPLMHVIAAKAVAFKEALSPEFK 291
Query: 326 VYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
YQ +VV N R L+E L + G +IV+G +++H++LVDLR+K G AE L A I N
Sbjct: 292 EYQQKVVENARVLAETLVKRGLRIVSGRTESHVMLVDLRAKHITGKAAEAALGAAHITVN 351
Query: 386 KNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KN P D SG+RLG+PA+T+RG + ++V + I +E + VRA
Sbjct: 352 KNAIPNDPEKPFVTSGIRLGSPAMTTRGFGPAEAEQVGNLIADVLENPEDAATIERVRAQ 411
Query: 445 LKEFKERLA 453
+ E +R
Sbjct: 412 VAELTKRFP 420
>5VC2-A nrPDB
Length = 424
Score = 580 bits (1495), Expect = e-166, Method: Composition-based stats.
Identities = 178/433 (41%), Positives = 265/433 (61%), Gaps = 29/433 (6%)
Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81
+A L+ +D E++ +I +E RQ LE+IASEN+ +V+EA+GS L NKY+EGYP +R
Sbjct: 9 MAYFLEQTDSEIFELIFEEYKRQNEHLEMIASENYTFPSVMEAMGSILTNKYAEGYPNKR 68
Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141
YYGG E +D++E+L +RA + + C NVQ +SGS AN AVY AL++P+ +I+G+
Sbjct: 69 YYGGCEVVDKIESLAIERAKKLF----NCQFANVQAHSGSQANNAVYHALLKPYDKILGM 124
Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201
DL GGHLTHG K+S T ++S Y VN D GYI+Y++ + A+ P++I+ G
Sbjct: 125 DLSCGGHLTHG-----AKVSLTGKHYQSFSYGVNLD-GYIDYEEALKIAQSVKPEIIVCG 178
Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261
S Y R +++ + R+IADE GA L+ D+AH++GLV PF HCHVV++TTHKTLRG
Sbjct: 179 FSAYPREIDFKKFREIADEVGALLLGDIAHVAGLVVTNEHAHPFPHCHVVSSTTHKTLRG 238
Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321
R G+I + + I+ A+FPG QGGP H IA AV K+ +
Sbjct: 239 PRGGIILTNDE--------------EIAAKIDKAIFPGTQGGPLMHVIAAKAVGFKENLK 284
Query: 322 LEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACS 381
EFK Y V +N + L++AL E +K+V+GG+ NHL+L+D K G A+ L
Sbjct: 285 PEFKAYAKLVKSNMQVLAKALKEKNHKLVSGGTSNHLLLMDFLDKPYSGKDADIALGNAG 344
Query: 382 IACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQ----KVAHFIHRGIELTLQIQ 436
I NKNT PG+ RS SG+R+G+ AL++RG+ K+F+ K++ ++ ++LQ+
Sbjct: 345 ITVNKNTIPGETRSPFVTSGIRIGSAALSARGMGAKEFEIIGNKISDILNDINNVSLQLH 404
Query: 437 SDTGVRATLKEFK 449
++A +F
Sbjct: 405 VKEELKAMANQFP 417
>4WXB-A nrPDB
Length = 428
Score = 564 bits (1454), Expect = e-161, Method: Composition-based stats.
Identities = 182/422 (43%), Positives = 264/422 (62%), Gaps = 25/422 (5%)
Query: 27 KDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGT 86
K D E++N I E+ RQ+ +ELIASEN S+AV+ A G+ L NKY+EGYPG+RYYGGT
Sbjct: 21 KAFDPELWNAIDAEAERQQNNIELIASENVVSKAVMAAQGTLLTNKYAEGYPGKRYYGGT 80
Query: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
ID +ETL +RA + + NVQP+SGS AN AVY +L++P +MG+DL G
Sbjct: 81 AVIDVVETLAIERAKKLFGA----KFANVQPHSGSQANAAVYMSLIQPGDTVMGMDLSAG 136
Query: 147 GHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS 206
GHLTHG +S + + + Y V+ ++ ++YD + A+ PKLI+AG S YS
Sbjct: 137 GHLTHG-----APVSFSGKTYNFVSYNVDKESELLDYDAILAQAKEVRPKLIVAGASAYS 191
Query: 207 RNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGM 266
R +++A+ R+IAD GAYLM DMAHI+GLVA+G PSP + HV TTTTHKTLRG R G+
Sbjct: 192 RIIDFAKFREIADAVGAYLMVDMAHIAGLVASGHHPSPVPYAHVTTTTTHKTLRGPRGGL 251
Query: 267 IFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKV 326
I ++ +NSAVFPGLQGGP H IA AVALK+A+ FK
Sbjct: 252 ILTDDE--------------DIAKKLNSAVFPGLQGGPLEHVIAAKAVALKEALDPAFKE 297
Query: 327 YQHQVVANCRALSEALTEL-GYKIVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACN 385
Y V+ N A+++ + +++++GG++NHL LVD+ +G A+ VLE +I N
Sbjct: 298 YGENVIKNAAAMADVFNQHPDFRVISGGTNNHLFLVDVTKVVENGKVAQNVLEEVNITLN 357
Query: 386 KNTCPGDR-SALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQIQSDTGVRAT 444
KN+ P ++ S + SG+R+G+PA+TSRG+ E + +++A ++ +E + + +R
Sbjct: 358 KNSIPYEQLSPFKTSGIRVGSPAITSRGMGEAESRQIAEWMVEALENHDKPEVLERIRGD 417
Query: 445 LK 446
+K
Sbjct: 418 VK 419
>3H7F-A nrPDB
Length = 447
Score = 561 bits (1445), Expect = e-160, Method: Composition-based stats.
Identities = 194/462 (41%), Positives = 259/462 (56%), Gaps = 54/462 (11%)
Query: 22 LAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQR 81
++ PL + D ++ ++ KE RQR LE+IASENF RAVL+A GS L NKY+EG PG+R
Sbjct: 22 MSAPLAEVDPDIAELLAKELGRQRDTLEMIASENFVPRAVLQAQGSVLTNKYAEGLPGRR 81
Query: 82 YYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGL 141
YYGG E +D +E L + RA + + NVQP+SG+ AN AV AL+ P R++GL
Sbjct: 82 YYGGCEHVDVVENLARDRAKALFGAE----FANVQPHSGAQANAAVLHALMSPGERLLGL 137
Query: 142 DLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAG 201
DL +GGHLTHG +++ + +E+ Y V+P T I+ D + A F PK+IIAG
Sbjct: 138 DLANGGHLTHGM-----RLNFSGKLYENGFYGVDPATHLIDMDAVRATALEFRPKVIIAG 192
Query: 202 TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRG 261
S Y R L++A R IADE GA L+ DMAH +GLVAAG+ PSP H VV+TT HKTL G
Sbjct: 193 WSAYPRVLDFAAFRSIADEVGAKLLVDMAHFAGLVAAGLHPSPVPHADVVSTTVHKTLGG 252
Query: 262 CRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMT 321
R+G+I ++ INSAVFPG QGGP H IAG AVALK A T
Sbjct: 253 GRSGLIVGKQ---------------QYAKAINSAVFPGQQGGPLMHVIAGKAVALKIAAT 297
Query: 322 LEFKVYQHQVVANCRALSEALT-----ELGYKIVTGGSDNHLILVDLRSKGTDGGRAEKV 376
EF Q + ++ R +++ L + G +V+GG+D HL+LVDLR DG AE +
Sbjct: 298 PEFADRQRRTLSGARIIADRLMAPDVAKAGVSVVSGGTDVHLVLVDLRDSPLDGQAAEDL 357
Query: 377 LEACSIACNKNTCPGD-RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 435
L I N+N P D R + SGLR+GTPAL +RG + +F +VA I + +
Sbjct: 358 LHEVGITVNRNAVPNDPRPPMVTSGLRIGTPALATRGFGDTEFTEVADIIATALATGSSV 417
Query: 436 QSDTGVRATLKEFKERLAGDKYQAAVQALREEVESFASLFPL 477
V AL++ A FPL
Sbjct: 418 D------------------------VSALKDRATRLARAFPL 435
>4BHD-A nrPDB
Length = 428
Score = 471 bits (1213), Expect = e-133, Method: Composition-based stats.
Identities = 143/443 (32%), Positives = 222/443 (50%), Gaps = 41/443 (9%)
Query: 27 KDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNNKYSEGYPGQRYYGGT 86
D + ++ K+ R ++LIASEN S AV EA + ++Y+EG PG+R Y G
Sbjct: 3 SDVPKFIRDVSIKQHEWMRESIKLIASENITSLAVREACATDFMHRYAEGLPGKRLYQGC 62
Query: 87 EFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDG 146
++IDE+ETLC + + + +K + NVQP SG AN AV+ A +P ++M L +PDG
Sbjct: 63 KYIDEVETLCIELSKELFKAE----HANVQPTSGVVANLAVFFAETKPGDKLMALSVPDG 118
Query: 147 GHLTHGFMTDKKKISATSIF-FESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCY 205
GH++H K+SA I + + + +P+ I+ D + + PKLI+ G S +
Sbjct: 119 GHISHW------KVSAAGIRGLKVINHPFDPEEMNIDADAMVKKILEEKPKLILFGGSLF 172
Query: 206 SRNLEYARLRKIADENGAYLMADMAHISGLVAAGVVPSPF-EHCHVVTTTTHKTLRGCRA 264
A + A E GA + D AH+ GL+A P E + +THKT G +
Sbjct: 173 PFPHPVADAYEAAQEVGAKIAYDGAHVLGLIAGKQFQDPLREGAEYLMGSTHKTFFGPQG 232
Query: 265 GMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF 324
G+I K I+S VFPG+ H H AG+A+AL A LEF
Sbjct: 233 GVILTTK---------------ENADKIDSHVFPGVVSNHHLHHKAGLAIAL--AEMLEF 275
Query: 325 -KVYQHQVVANCRALSEALTELGYKIVTGGSD---NHLILVDLRSKGT---DGGRAEKVL 377
+ Y QV+ N +AL++AL E G+ ++ D +H +++D+ S K+
Sbjct: 276 GEAYAKQVIKNAKALAQALYERGFNVLCEHKDFTESHQVIIDIESSPDIEFSASELAKMY 335
Query: 378 EACSIACNKNTCPGD--RSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIELTLQI 435
E +I NKN P D ++ PSG+RLGT T G+ EK+ +++A F+ R + +
Sbjct: 336 EEANIILNKNLLPWDDVNNSDNPSGIRLGTQECTRLGMKEKEMEEIAEFMKR---IAIDK 392
Query: 436 QSDTGVRATLKEFKERLAGDKYQ 458
+ VR +KEF + + Y
Sbjct: 393 EKPEKVREDVKEFAKEYSTIHYS 415
>3TQX-A nrPDB
Length = 399
Score = 53.5 bits (127), Expect = 2e-07, Method: Composition-based stats.
Identities = 58/313 (18%), Positives = 112/313 (35%), Gaps = 46/313 (14%)
Query: 123 ANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYIN 182
AN ++ L+ P I+ L H + D ++ ++ Y+ + +
Sbjct: 115 ANGGLFETLLGPEDAIIS------DELNHASIIDGIRLC------KAQRYRYKNNAMG-D 161
Query: 183 YDQLEENARLF--HPKLIIAG--TSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAA 238
+ + A KLI S + + +AD+ A +M D +H G +
Sbjct: 162 LEAKLKEADEKGARFKLIATDGVFSMDGIIADLKSICDLADKYNALVMVDDSHAVGFIGE 221
Query: 239 GVVPSPFEHC------HVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLI 292
+P E+C ++T T K L G G Y G K + L S
Sbjct: 222 NGRGTP-EYCGVADRVDILTGTLGKALGGASGG---YTSGHKEIIEWLRNRSRPYLFS-- 275
Query: 293 NSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTG 352
+ V P I ++ + + + E + Q+ N R + +LG+++V G
Sbjct: 276 -NTVAP---------VIVATSLKVLELLKTEGPQLRKQLQENSRYFRAGMEKLGFQLVPG 325
Query: 353 GSDNHLIL-VDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSR 411
NH I+ V L A+ +L+ I + P + + +R+ A+ ++
Sbjct: 326 ---NHPIIPVMLGDAQLATNMADHLLQE-GIYVVGFSYP--VVPMGKARIRVQMSAVHTQ 379
Query: 412 GLLEKDFQKVAHF 424
L++ +
Sbjct: 380 QQLDRAIEAFGQV 392
>1M6S-A nrPDB
Length = 347
Score = 44.3 bits (103), Expect = 1e-04, Method: Composition-based stats.
Identities = 56/323 (17%), Positives = 111/323 (34%), Gaps = 56/323 (17%)
Query: 79 GQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRI 138
G YG I+ELE L A + + + + SG+ N A + +
Sbjct: 30 GDDVYGEDPTINELERL----AAETFGKEAALFVP-----SGTMGNQVSIMAHTQRGDEV 80
Query: 139 MGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENAR---LFHP 195
+ L H+ ++ A ++ MP+ V G ++ D + + R + P
Sbjct: 81 I---LEADSHI------FWYEVGAMAVLSGVMPHPVPGKNGAMDPDDVRKAIRPRNIHFP 131
Query: 196 KL-IIAGTSCYSR----NLEYARLRKI---ADENGAYLMADMAHI-SGLVAAGVVPSPFE 246
+ +IA + ++R + +++I A E+G + D A I + +A+GV P +
Sbjct: 132 RTSLIAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGV---PVK 188
Query: 247 ----HCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQG 302
+ V K L ++ + K K + + Q
Sbjct: 189 EYAGYADSVMFCLSKGLCAPVGSVVVGDRDFIERARKARKMLGGGMR-----------QA 237
Query: 303 GPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVD 362
G +A + M K N R L+ L E+GY + +++++
Sbjct: 238 G----VLAAAGIIALTKMVDRLKEDHE----NARFLALKLKEIGYSVNPEDVKTNMVILR 289
Query: 363 LRSKGTDGGRAEKVLEACSIACN 385
+ + + L + N
Sbjct: 290 TDNLKVNAHGFIEALRNSGVLAN 312
>3WY7-A nrPDB
Length = 404
Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats.
Identities = 36/177 (20%), Positives = 64/177 (36%), Gaps = 23/177 (12%)
Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT 178
SG AN AL P L L+H + D ++S + P++
Sbjct: 125 SGYTANLGALVALSGPG------SLIVSDALSHASLVDACRLSRARVV--VSPHRDVDAV 176
Query: 179 GYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRK---IADENGAYLMADMAHISGL 235
+ EE A ++ S +S + + A LR + +GA L+ D AH G+
Sbjct: 177 DAALAARTEERA-------VVVTESVFSADGDLAPLRDLHAVCRRHGALLLVDEAHGLGV 229
Query: 236 VAAG----VVPSPFEHC-HVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYN 287
+ +V TTT G + G + + V++ T + +++
Sbjct: 230 RGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVLGPEAVRAHLIDTARSFIFD 286
>1CS1-A nrPDB
Length = 386
Score = 42.7 bits (99), Expect = 4e-04, Method: Composition-based stats.
Identities = 31/170 (18%), Positives = 61/170 (35%), Gaps = 29/170 (17%)
Query: 97 QKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTD 156
+RAL + + V +G A V T ++P ++ GG
Sbjct: 57 VQRAL----AELEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGG--------- 103
Query: 157 KKKISATSIFFESMPYKVNPDTGYINY--DQLEENARLFHPKLIIAGTSCYS--RNLEYA 212
+ F+S+ + +++ +Q A PKL++ + R ++ A
Sbjct: 104 ------SYRLFDSLAKRGCYRVLFVDQGDEQALRAALAEKPKLVLVESPSNPLLRVVDIA 157
Query: 213 RLRKIADENGAYLMADMAHISGLVAAGVVPSPFE-HCHVVTTTTHKTLRG 261
++ +A E GA + D +S + +P +V + K L G
Sbjct: 158 KICHLAREVGAVSVVDNTFLS-----PALQNPLALGADLVLHSCTKYLNG 202
>4BMK-A nrPDB
Length = 442
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 80/412 (19%), Positives = 149/412 (36%), Gaps = 69/412 (16%)
Query: 11 DADLWSSHDKMLAQPLKDSDVEV---YNIIKKESN-------RQRVGLELIASENFA--- 57
+ DL S D ++A+ K D V + I+ ++ R + + L+ + N+
Sbjct: 42 ERDLLSKFDGLIAERQKLLDSGVTDPFAIVMEQVKSPTEAVIRGKDTI-LLGTYNYMGMT 100
Query: 58 -SRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQ 116
V+ A G K+ G G R GT F D +E ++AL+ + G V
Sbjct: 101 FDPDVIAA-GKEALEKFGSGTNGSRMLNGT-FHDHME---VEQALRDF---YGTTGAIVF 152
Query: 117 PYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNP 176
+G AN + + L ++ L H + + S+
Sbjct: 153 -STGYMANLGIISTLAGKGEYVI---LDADSHASIYDGCQQGNAEIVRFRHNSVE----- 203
Query: 177 DTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRK---IADENGAYLMADMAHIS 233
+ D+ KL++ YS + A L++ +A ++GA ++ D AH
Sbjct: 204 -----DLDKRLGRLPKEPAKLVVLEG-VYSMLGDIAPLKEMVAVAKKHGAMVLVDEAHSM 257
Query: 234 GLVAA---GVV-PSPFEH-CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNL 288
G GV E V T ++ G G + S PK L
Sbjct: 258 GFFGPNGRGVYEAQGLEGQIDFVVGTFSASV-GTVGGFVV------SNHPKFEAVRLACR 310
Query: 289 ESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYK 348
+ +++ P +A ++++ MT K + ++ +N RAL L +G++
Sbjct: 311 PYIFTASLPPS--------VVATATTSIRKLMTAHEK--RERLWSNARALHGGLKAMGFR 360
Query: 349 IVTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSG 400
+ T D+ ++ V L + + +L+ + N R P+G
Sbjct: 361 LGTETCDSAIVAVMLEDQEQAAMMWQALLDG-GLYVN-----MARPPATPAG 406
>2X8U-A nrPDB
Length = 412
Score = 40.4 bits (93), Expect = 0.002, Method: Composition-based stats.
Identities = 62/350 (17%), Positives = 114/350 (32%), Gaps = 61/350 (17%)
Query: 64 ALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPA 123
A G +++ G G R GT + C+ + Y + +G A
Sbjct: 65 AAGKQALDEFGSGTTGSRVLNGTYQGHKA---CEDALKEFYGTEHAIVFS-----TGYQA 116
Query: 124 NFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINY 183
N + + L I+ L H + S+ ++ G +
Sbjct: 117 NLGMISTLAGKGDYII---LDADSHASIYDGCWLGDAEIVRFRHNSVE-DLDKRLGRLPA 172
Query: 184 DQLEENARLFHPKLIIAGTSCYSRNLEYARLRK---IADENGAYLMADMAHISGLVA--- 237
+ + YS + A L++ ++ ++GA ++ D AH G
Sbjct: 173 EAGKLVVLE----------GVYSMMGDIAPLQEMVAVSKKHGAMILVDEAHGMGFFGEHG 222
Query: 238 ------AGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESL 291
AGV V T K++ G G S PK L +
Sbjct: 223 RGVFEEAGVEAD----VDFVVGTFSKSV-GTVGGF------CVSNHPKFEVLRLVCRPYV 271
Query: 292 INSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVT 351
+++ P +A A ++++ M K + + N R L + L ++GYK+ T
Sbjct: 272 FTASLPPS--------VVATAATSIRKLMHAGDK--RAHLWKNSRRLHQGLRDMGYKLGT 321
Query: 352 GGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGL 401
+ + +I V L + +LE + N R P+G+
Sbjct: 322 ETAQSAIIAVILTDMAQAVALWQGLLE-AGLYVN-----TARPPATPAGM 365
>3A2B-A nrPDB
Length = 398
Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats.
Identities = 64/345 (18%), Positives = 119/345 (34%), Gaps = 65/345 (18%)
Query: 72 KYSEGYPGQRYYGGTE--FIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYT 129
KY G G R+ GT ++ E L +A L +G +N +
Sbjct: 72 KYGTGCAGSRFLNGTLDIHVELEEKLSAYVGKEAAILFS----------TGFQSNLGPLS 121
Query: 130 ALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEEN 189
L+ + I+ LD D H + D ++S + + + Y N N + L
Sbjct: 122 CLMGRNDYIL-LDERD-----HASIIDGSRLSFS----KVIKYGHN------NMEDLRAK 165
Query: 190 AR---LFHPKLIIAG--TSCYSRNLEYARLRKIADENGAYLMADMAHISGLV-----AAG 239
KLI S + L IA+E A +M D AH G++
Sbjct: 166 LSRLPEDSAKLICTDGIFSMEGDIVNLPELTSIANEFDAAVMVDDAHSLGVIGHKGAGTA 225
Query: 240 VVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPG 299
+ ++ T K+L G + V + ++++ +++ P
Sbjct: 226 SHFGLNDDVDLIMGTFSKSLAS-LGGFVAGDADVIDFLKHNARSVMFS------ASMTP- 277
Query: 300 LQGGPHNHAIAGVAVALK--QAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNH 357
A VA LK + + E + ++ N L + G+ + G +++
Sbjct: 278 ----------ASVASTLKALEIIQNE-PEHIEKLWKNTDYAKAQLLDHGFDL--GATESP 324
Query: 358 LILVDLRSKGTDGGRAEKVLEACSIACN---KNTCPGDRSALRPS 399
++ + +RS K+L+ + N P + S +R S
Sbjct: 325 ILPIFIRSNEKT-FWVTKMLQDDGVFVNPVVSPAVPAEESLIRFS 368
>2AEV-A nrPDB
Length = 374
Score = 38.9 bits (89), Expect = 0.005, Method: Composition-based stats.
Identities = 21/107 (19%), Positives = 43/107 (40%), Gaps = 8/107 (7%)
Query: 197 LIIAGTSCYSRNLEYARLRKI---ADENGAYLMADMAHISGLVAAGVVPSPFE---HCHV 250
+II G++ + +E +K+ A A + D A SG + P +
Sbjct: 144 VIITGSTMDLKVIELENFKKVINTAKNKEAIVFVDDA--SGARVRLLFNQPPALKLGADL 201
Query: 251 VTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVF 297
V T+T K + G R G++ +K + G + + + + ++
Sbjct: 202 VVTSTDKLMEGPRGGLLAGKKELVDKIYIEGTKFGLEAQPPLLAGIY 248
>2BWN-A nrPDB
Length = 401
Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats.
Identities = 49/218 (22%), Positives = 77/218 (35%), Gaps = 31/218 (14%)
Query: 195 PKLIIAGTSCYSRNLEYARLRKIAD---ENGAYLMADMAHISGLV----AAGVVPSPFEH 247
PKLI A S YS + ++ +++I D E GA D H G+ A H
Sbjct: 179 PKLI-AFESVYSMDGDFGPIKEICDIAEEFGALTYIDEVHAVGMYGPRGAGVAERDGLMH 237
Query: 248 -CHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHN 306
+ T K G G I + VD + + + A+ G Q
Sbjct: 238 RIDIFNGTLAKAY-GVFGGYI--AASARMVDAVRSYAPGFIFSTSLPPAIAAGAQA---- 290
Query: 307 HAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLILVDLRSK 366
+IA + A Q + Q+ + + L L LG I+ GS H++ V +
Sbjct: 291 -SIAFLKTAEGQKLRD-----AQQM--HAKVLKMRLKALGMPIIDHGS--HIVPVVIGDP 340
Query: 367 GTDGGRAEKVLEACSIAC---NKNTCP--GDRSALRPS 399
++ +L + N T P +R PS
Sbjct: 341 VHTKAVSDMLLSDYGVYVQPINFPTVPRGTERLRFTPS 378
>3NNK-A nrPDB
Length = 411
Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats.
Identities = 40/214 (18%), Positives = 72/214 (33%), Gaps = 36/214 (16%)
Query: 57 ASRAVLEALGSCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQ 116
A VL A+ S L +Y P +Y E + R ++ + W + V
Sbjct: 24 ADPRVLRAMSSQLIGQYD---PAMTHYMN-------EVMALYRG--VFRTE-NRWTMLVD 70
Query: 117 PYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNP 176
S + A+ + + P +++ +P G H ++ A E +P+
Sbjct: 71 GTSRAGIE-AILVSAIRPGDKVL---VPVFGRFGHLLCEIARRCRAEVHTIE-VPWG--- 122
Query: 177 DTGYINYDQLEENARLFHPKLI--IAGTSCYSRNLEYARLRKIADENGAYLMADMAHISG 234
DQ+E+ + P+L+ + G + + A L +I A D
Sbjct: 123 --EVFTPDQVEDAVKRIRPRLLLTVQGDTSTTMLQPLAELGEICRRYDALFYTD------ 174
Query: 235 LVAAGVVPSPFE----HCHVVTTTTHKTLRGCRA 264
A + +P E V+ K L G
Sbjct: 175 -ATASLGGNPLETDVWGLDAVSAGMQKCLGGPSG 207
>1FC4-A nrPDB
Length = 401
Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats.
Identities = 40/215 (18%), Positives = 73/215 (33%), Gaps = 31/215 (14%)
Query: 182 NYDQLEENARLFHPK----LIIAGTSCYSRNLEYARLR---KIADENGAYLMADMAHISG 234
+ +LE + ++IA +S + A L+ +AD+ A +M D +H G
Sbjct: 160 DMQELEARLKEAREAGARHVLIATDGVFSMDGVIANLKGVCDLADKYDALVMVDDSHAVG 219
Query: 235 LVAAG-----VVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLE 289
V ++T T K L G G RK V + +
Sbjct: 220 FVGENGRGSHEYCDVMGRVDIITGTLGKALGGASGGYTAARKEVVEWLRQRSR------- 272
Query: 290 SLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
P L AI ++ + + M + ++ AN R E ++ G+ +
Sbjct: 273 --------PYLFSNSLAPAIVAASIKVLE-MVEAGSELRDRLWANARQFREQMSAAGFTL 323
Query: 350 VTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIAC 384
G+D H I+ + + + L+ I
Sbjct: 324 --AGAD-HAIIPVMLGDAVVAQKFARELQKEGIYV 355
>3OP7-A nrPDB
Length = 375
Score = 37.3 bits (85), Expect = 0.016, Method: Composition-based stats.
Identities = 28/121 (23%), Positives = 54/121 (44%), Gaps = 19/121 (15%)
Query: 115 VQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKV 174
+Q + AN V +L+EP ++ L + T+ + D K S+ E +++
Sbjct: 85 LQTNGATGANLLVLYSLIEPGDHVISL------YPTYQQLYDIPK----SLGAEVDLWQI 134
Query: 175 NPDTGYINYDQLEENARLFHP--KLIIAGTSCYSR--NLE---YARLRKIADENGAYLMA 227
+ G++ LE+ +L P K+I + ++ L +IA E GAY+++
Sbjct: 135 EEENGWL--PDLEKLRQLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEVGAYILS 192
Query: 228 D 228
D
Sbjct: 193 D 193
>4AOA-A nrPDB
Length = 454
Score = 35.8 bits (81), Expect = 0.045, Method: Composition-based stats.
Identities = 26/119 (21%), Positives = 44/119 (36%), Gaps = 16/119 (13%)
Query: 118 YSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPD 177
SG+ AN TA + GR + G H G + + S T++ F+ + N
Sbjct: 150 NSGTEANLMALTAALHFTGRRKIVVFSGGYH--GGVLGFGARPSPTTVPFDFLVLPYN-- 205
Query: 178 TGYINYDQLEENARLFHPKLIIA------GTS-CYSRNLEY-ARLRKIADENGAYLMAD 228
+ P++ + G S C ++ LR+ A + GA L+ D
Sbjct: 206 ----DAQTARAQIERHGPEIAVVLVEPMQGASGCIPGQPDFLQALRESATQVGALLVFD 260
>1PQU-A nrPDB
Length = 371
Score = 34.3 bits (77), Expect = 0.11, Method: Composition-based stats.
Identities = 29/162 (17%), Positives = 51/162 (31%), Gaps = 18/162 (11%)
Query: 316 LKQAMTLEFKVYQHQVVA-----NCRALSEALTELGYKIVTGGSDNHLILVDLRSK--GT 368
L+QA++ E K ++ + ++ + GGS L+ K
Sbjct: 183 LEQAVSSELKDPASSILDIERKVTAKMRADNFPTDNFGAALGGS-----LIPWIDKLLPE 237
Query: 369 DGGRAEKVLEACS----IACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHF 424
G E+ + + N P D +R LR + A T + + +++
Sbjct: 238 TGQTKEEWKGYAETNKILGLSDNPIPVDGLCVRIGALRCNSQAFTIKLKKDLPLEEIEQI 297
Query: 425 IHRGIELTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALRE 466
I E I TL+E V LR+
Sbjct: 298 IASHNEWVKVI--PNDKEITLRELTPAKVTGTLSVPVGRLRK 337
>3BB8-A nrPDB
Length = 437
Score = 34.3 bits (77), Expect = 0.14, Method: Composition-based stats.
Identities = 32/167 (19%), Positives = 56/167 (33%), Gaps = 21/167 (12%)
Query: 118 YSGSPANFAVYTAL---------VEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFE 168
SGS AN TAL ++P ++ + GF T +
Sbjct: 84 TSGSSANLLALTALTSPKLGVRALKPGDEVIT--------VAAGFPTTVNPTIQNGLI-- 133
Query: 169 SMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMAD 228
+ V+ T +N +E A K I+ + + A +R++AD+ +L+ D
Sbjct: 134 PVFVDVDIPTYNVNASLIEA-AVSDKTKAIMIAHTL-GNLFDLAEVRRVADKYNLWLIED 191
Query: 229 MAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKS 275
G G + F V+ K + G +F +
Sbjct: 192 CCDALGSTYDGKMAGTFGDIGTVSFYPAKHITMGEGGAVFTQSAELK 238
>6ONN-A nrPDB
Length = 402
Score = 33.9 bits (76), Expect = 0.16, Method: Composition-based stats.
Identities = 30/122 (24%), Positives = 49/122 (40%), Gaps = 20/122 (16%)
Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT 178
+G AN A TAL + L H + D ++S I + P+
Sbjct: 119 TGYMANLATLTALAGRGTTLFSDS------LNHASLIDGARLSRADI--QIYPHA----- 165
Query: 179 GYINYDQLEEN--ARLFHPKLIIAG--TSCYSRNLEYARLRKIADENGAYLMADMAHISG 234
+ + L A KLI++ S ARL ++A+ +GA+L+ D AH G
Sbjct: 166 ---DAEALGAMLEASDAAVKLIVSDTVFSMDGDIAPLARLLELAEHHGAWLVVDDAHGFG 222
Query: 235 LV 236
++
Sbjct: 223 VL 224
>5JAY-A nrPDB
Length = 402
Score = 33.5 bits (75), Expect = 0.23, Method: Composition-based stats.
Identities = 49/301 (16%), Positives = 104/301 (34%), Gaps = 51/301 (16%)
Query: 119 SGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDT 178
+G AN A TAL + L H + D ++S + Y
Sbjct: 119 TGYMANLATLTALAGRGTTLFS------DALNHASLIDGARLSRA----DVQIYP----- 163
Query: 179 GYINYDQLEEN--ARLFHPKLIIAGTSCYSRNLEYA---RLRKIADENGAYLMADMAHIS 233
+ + D L A K+I++ + +S + + A RL ++A+++GA+L+ D AH
Sbjct: 164 -HCDTDALSAMLEASDADVKVIVSD-TVFSMDGDIAPLPRLLELAEQHGAWLIVDDAHGF 221
Query: 234 GLVA----AGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLE 289
G++ + + ++++ T G + + V + + ++
Sbjct: 222 GVLGPQGRGAIAQAALRSPNLISIGTLDKAAGVSGAFVAAHETVIEWLVQRARPYIFTTA 281
Query: 290 SLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKI 349
S+ +A HA++ + + + Q++ RA+ L +
Sbjct: 282 SVPAAA-----------HAVSASLRIIGGEEGDARRAHLQQLIGRTRAM---LKATPWLP 327
Query: 350 VTGGSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSG---LRLGTP 406
V + +++ L+ + P R P+G LR+
Sbjct: 328 VDSHTAVQPLIIGANDATL---EIAATLDRAGL-----WVPAIRPPTVPTGTSRLRISLS 379
Query: 407 A 407
A
Sbjct: 380 A 380
>6NPB-A nrPDB
Length = 383
Score = 33.5 bits (75), Expect = 0.23, Method: Composition-based stats.
Identities = 14/65 (21%), Positives = 25/65 (38%), Gaps = 1/65 (1%)
Query: 117 PYSGSPANFAVYTALVE-PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVN 175
P + SP N + + P + L D G LT F + K ++ + +S Y +
Sbjct: 44 PETRSPGNGQRLITIGDIPADTRISTALVDDGALTVTFAPEGKTVTFPGKWLKSNAYDTD 103
Query: 176 PDTGY 180
+
Sbjct: 104 QSSEV 108
>3TRI-A nrPDB
Length = 280
Score = 33.1 bits (74), Expect = 0.26, Method: Composition-based stats.
Identities = 31/161 (19%), Positives = 56/161 (34%), Gaps = 15/161 (9%)
Query: 316 LKQAMTLEFKVYQHQVVANCRALSEALTELGYKIVTGG-----SDNHLILVDLRSKGTDG 370
K+ + Q N + A+ K+V S+ ++++ L + G
Sbjct: 45 FKEKCGVHTTQDNRQGALNADVVVLAVKPHQIKMVCEELKDILSETKILVISL-AVGVTT 103
Query: 371 GRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRGLLEKDFQKVAHFIHRGIE 430
EK L S P PS +R G L + ++KD + +A I R +
Sbjct: 104 PLIEKWLGKASRIVR--AMPN-----TPSSVRAGATGLFANETVDKDQKNLAESIMRAVG 156
Query: 431 LTLQIQSDTGVRATLKEFKERLAGDKYQAAVQALREEVESF 471
L + + S+ + A ++AL+E E
Sbjct: 157 LVIWVSSEDQIEKIAALSGSGPAYIFLI--MEALQEAAEQL 195
>3WPR-A nrPDB
Length = 229
Score = 33.1 bits (74), Expect = 0.28, Method: Composition-based stats.
Identities = 30/157 (19%), Positives = 50/157 (31%), Gaps = 19/157 (12%)
Query: 299 GLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIV------TG 352
G GP + G + A+T + S++ G IV
Sbjct: 57 GTITGPTYNVAQGNQTNVGDALTA-----LDNAINTAATTSKSTVSNGQNIVVSKSKNAD 111
Query: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRG 412
GSDN+ + + VL I N + + L S G P++T G
Sbjct: 112 GSDNYEVSTAKDLTVDSVKAGDTVLNNAGITIGNNAVVLNNTGLTIS----GGPSVTLAG 167
Query: 413 L--LEKDFQKVAHFIH--RGIELTLQIQSDTGVRATL 445
+ K Q VA+ ++ + Q + + L
Sbjct: 168 IDAGNKTIQNVANAVNATDAVNKGQMKQIEDKIEEIL 204
>5K1R-A nrPDB
Length = 480
Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats.
Identities = 30/182 (16%), Positives = 59/182 (32%), Gaps = 20/182 (10%)
Query: 167 FESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYS-RNLE-YARLRKIADENGAY 224
F+ ++P T ++ D + + A + +++ Y ++ L IA E +
Sbjct: 171 FDVTVAPIDPVTMQVDADFVRD-AVDANTVMLVGSACNYPYGTIDPIGALSAIAVEKDVW 229
Query: 225 LMADMAHISGLVAAGV---VPS-P-----FEHCHVVTTTTHKTLRGCRAGMIFYRKGVKS 275
L D ++ G P P ++ THK G + G + +
Sbjct: 230 LHVDGCLGGWMLPWGEALGYPDIPAFDFRLPGVTSISADTHKFGYGPKGGSVLAWR---- 285
Query: 276 VDPKTGKEILYNLESLINSAVF--PGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVA 333
D + + + + V+ PGL G IA AL+ + +
Sbjct: 286 -DASFRRHQYFLMTDWV-GGVYGSPGLTGSRSGGLIAATWAALRSLGREGYLARAKAIFE 343
Query: 334 NC 335
Sbjct: 344 TA 345
>5XT5-A nrPDB
Length = 419
Score = 33.1 bits (74), Expect = 0.31, Method: Composition-based stats.
Identities = 27/170 (15%), Positives = 61/170 (35%), Gaps = 19/170 (11%)
Query: 114 NVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYK 173
N+ S + AN ++P ++ + ++ + AT + +P +
Sbjct: 100 NMVALSYARAN-------LKPGDEVVITYMEHHANIIPWQQA----VKATGATLKYIPLQ 148
Query: 174 VNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNL-EYARLRKIADENGAYLMADMAHI 232
+ G I+ + + E + ++ S + + KIA +NGA ++ D A
Sbjct: 149 ---EDGTISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGAVIVVDGAQS 205
Query: 233 SGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVKSVDPKTGK 282
+ + V C ++HK + G + Y K + + +
Sbjct: 206 TPHMKIDVQD---LDCDFFALSSHK-MCGPTGVGVLYGKKALLENMEPAE 251
>5JWG-A nrPDB
Length = 703
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 22/77 (28%), Positives = 31/77 (40%), Gaps = 13/77 (16%)
Query: 19 DKMLAQPLKDSDVEVYNIIKKESNRQR--VGLELIASENFASRAVLEALGSCLNNKYSEG 76
+ L + D +V +KKE R + GLE F S L +L + K +
Sbjct: 97 NPGLEVEIVDEITDVTAAVKKELERIKKPSGLE------FLSPRYLSSLAPEIVGKKAAS 150
Query: 77 YPGQRY-----YGGTEF 88
PG RY YGG +
Sbjct: 151 RPGYRYEIKAFYGGNRY 167
>3WGB-A nrPDB
Length = 341
Score = 32.7 bits (73), Expect = 0.39, Method: Composition-based stats.
Identities = 33/202 (16%), Positives = 69/202 (34%), Gaps = 18/202 (8%)
Query: 100 ALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKK 159
AL+AY D + SG+ +N + + G L H+ + +
Sbjct: 43 ALEAYGADLLGKEAALFVPSGTMSNLLAVMSHCQRGE---GAVLGSAAHI-YRYEAQGSA 98
Query: 160 ISATSIFFESMPYKVNPDTGYINY-DQLEENARLFHPKLIIAGTSCYSR---NLEYAR-L 214
+ S+ + +P + + + + + F P ++ + ++ L Y R +
Sbjct: 99 V-LGSVALQPVPMQADGSLALADVRAAIAPDDVHFTPTRLVCLENTHNGKVLPLPYLREM 157
Query: 215 RKIADENGAYLMADMAHISGLVAAGVVP-----SPFEHCHVVTTTTHKTLRGCRAGMIFY 269
R++ DE+G L D A + V A +PF V+ K L ++
Sbjct: 158 RELVDEHGLQLHLDGARLFNAVVASGHTVRELVAPF---DSVSICLSKGLGAPVGSLLVG 214
Query: 270 RKGVKSVDPKTGKEILYNLESL 291
+ + K + +
Sbjct: 215 SHAFIARARRLRKMVGGGMRQA 236
>6G21-A nrPDB
Length = 507
Score = 32.3 bits (72), Expect = 0.42, Method: Composition-based stats.
Identities = 26/166 (15%), Positives = 54/166 (32%), Gaps = 47/166 (28%)
Query: 15 WSSHDKMLAQPLKD---SDVEVYNIIKKESNRQRVGLE-----LIASENFASRAVLEALG 66
WS+H + P+ +++NI KE RQ G++ +I + S VLEA+
Sbjct: 204 WSAHFYSITGPVGSDTYLSPDLWNITHKEILRQCDGIDGAEDGIIEDPSLCSP-VLEAII 262
Query: 67 SCLNNKYSEGYPGQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFA 126
+E G++ + + + P G N
Sbjct: 263 CKPGQNTTECLTGKQAH---------------TVREIFS-----------PLYGV--NGT 294
Query: 127 VYTALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPY 172
+ ++P +M + G + ++ ++ + Y
Sbjct: 295 LLYPRMQPGSEVMASSIMYNG----------QPFQYSADWYRYVVY 330
>2OKJ-A nrPDB
Length = 504
Score = 32.3 bits (72), Expect = 0.49, Method: Composition-based stats.
Identities = 21/103 (20%), Positives = 33/103 (32%), Gaps = 11/103 (10%)
Query: 168 ESMPYKVNPDTGYINYDQLEENARLFHPKLII-------AGTSCYSRNLEYARLRKIADE 220
+ K N I D E K + AGT+ Y + I ++
Sbjct: 215 NVILIKCNERGKIIPAD-FEAKILEAKQKGYVPFYVNATAGTTVYGAFDPIQEIADICEK 273
Query: 221 NGAYLMADMAHISGLVAAGVVP---SPFEHCHVVTTTTHKTLR 260
+L D A GL+ + + E + VT HK +
Sbjct: 274 YNLWLHVDAAWGGGLLMSRKHRHKLNGIERANSVTWNPHKMMG 316
>5HH9-A nrPDB
Length = 390
Score = 32.0 bits (71), Expect = 0.60, Method: Composition-based stats.
Identities = 45/258 (17%), Positives = 85/258 (32%), Gaps = 32/258 (12%)
Query: 115 VQP----YSGSPAN--FAVYTALV-EPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFF 167
VQP +GS + A+Y L+ +P I+ + T+ + + K T
Sbjct: 74 VQPGQVALTGSTTDGLAAIYGGLLVQPGKEILTSSHEH--YSTYTTLEYRHKRMGT---- 127
Query: 168 ESMPYKVNPDTGYINYDQLEE-NARLFHPKLIIAGT----SCYSRNLEYARLRKIADENG 222
+ + + D ++ D++ A P+ + G S L + K+ E
Sbjct: 128 QVREFPLFKDPHRVSADEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELN 187
Query: 223 AY--------LMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKGVK 274
+ D H G V + F+ C THK L G R + + +
Sbjct: 188 QKRDEQDRIIYVVDGVH--GFGVEDVSFADFD-CDYFIAGTHKWLFGPRGTGVIIARSEQ 244
Query: 275 SVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVAN 334
+ ++ + + PG G + A + + L Q ++
Sbjct: 245 LQEHLVPSIPTFSRADNFGTLMTPG--GYHAFEHRLALGTAFELHLQLGKAEVQARIHQL 302
Query: 335 CRALSEALTEL-GYKIVT 351
L + L E ++VT
Sbjct: 303 NAYLKQRLGEHPKVRLVT 320
>3Q8X-B nrPDB
Length = 287
Score = 32.0 bits (71), Expect = 0.69, Method: Composition-based stats.
Identities = 23/101 (22%), Positives = 40/101 (39%), Gaps = 17/101 (16%)
Query: 266 MIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGVAVALKQAMTLEF- 324
+I +K V+S + ++ + SA+F QG + I KQ F
Sbjct: 23 LIQGKKAVESPTAFLLGGQPGSGKTSLRSAIFEETQG----NVIVIDNDTFKQQH-PNFD 77
Query: 325 ---KVYQHQVVAN--------CRALSEALTELGYKIVTGGS 354
K+Y+ VV + A+ L++ GY +V G+
Sbjct: 78 ELVKLYEKDVVKHVTPYSNRMTEAIISRLSDQGYNLVIEGT 118
>5TXT-B nrPDB
Length = 491
Score = 31.6 bits (70), Expect = 0.70, Method: Composition-based stats.
Identities = 24/78 (30%), Positives = 35/78 (44%), Gaps = 14/78 (17%)
Query: 182 NYDQLEENARLFH---PKLIIAGTSCYS---RNLEYARLRKIADENGAYLMADMAHISGL 235
+ ++LE+ + + PKLI A S YS + ++ +AD+ GA D H GL
Sbjct: 173 DLNELEQLLQSYPKSVPKLI-AFESVYSMAGSVADIEKICDLADKYGALTFLDEVHAVGL 231
Query: 236 V---AAGVVPSPFEHCHV 250
AGV EHC
Sbjct: 232 YGPHGAGV----AEHCDF 245
>3WPA-A nrPDB
Length = 427
Score = 31.6 bits (70), Expect = 0.70, Method: Composition-based stats.
Identities = 28/136 (20%), Positives = 45/136 (33%), Gaps = 17/136 (12%)
Query: 299 GLQGGPHNHAIAGVAVALKQAMTLEFKVYQHQVVANCRALSEALTELGYKIV------TG 352
G GP + G + A+T + S++ G IV
Sbjct: 57 GTITGPTYNVAQGNQTNVGDALTA-----LDNAINTAATTSKSTVSNGQNIVVSKSKNAD 111
Query: 353 GSDNHLILVDLRSKGTDGGRAEKVLEACSIACNKNTCPGDRSALRPSGLRLGTPALTSRG 412
GSDN+ + + VL I N + + L S G P++T G
Sbjct: 112 GSDNYEVSTAKDLTVDSVKAGDTVLNNAGITIGNNAVVLNNTGLTIS----GGPSVTLAG 167
Query: 413 L--LEKDFQKVAHFIH 426
+ K Q VA+ ++
Sbjct: 168 IDAGNKTIQNVANAVN 183
>1XI9-A nrPDB
Length = 406
Score = 31.6 bits (70), Expect = 0.77, Method: Composition-based stats.
Identities = 16/61 (26%), Positives = 28/61 (45%), Gaps = 1/61 (1%)
Query: 79 GQRYYGGTEFIDELETLCQKRALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRI 138
G YYG +E + EL +R + +D V V + + A ++ AL++P I
Sbjct: 70 GHNYYGDSEGLPELRKAIVEREKRKNGVDITPDDVRVTA-AVTEALQLIFGALLDPGDEI 128
Query: 139 M 139
+
Sbjct: 129 L 129
>1GC4-A nrPDB
Length = 385
Score = 31.6 bits (70), Expect = 0.80, Method: Composition-based stats.
Identities = 42/232 (18%), Positives = 81/232 (34%), Gaps = 52/232 (22%)
Query: 33 VYNIIKKESNRQRVGLELIA---------SENFASRAVLEALGSCLNNKYS--EGYPGQR 81
V + K +R G++L+A + A AL KY+ G P R
Sbjct: 16 VVAVNAKALELRRQGVDLVALTAGEPDFDTPEHVKEAARRALAQGKT-KYAPPAGIPELR 74
Query: 82 YYGGTEFIDELETLCQK-RALQAYKLDPQCWGVNVQPYSGSPANFAVYTALVEPHGRIMG 140
E L +K R + P+ V V GS A F ++ A+++P ++
Sbjct: 75 -----------EALAEKFRRENGLSVTPEETIVTV---GGSQALFNLFQAILDPGDEVIV 120
Query: 141 LDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIA 200
L+ +++ + + + + P+ G++ + A K ++
Sbjct: 121 --------LSPYWVSYPEMVRFAGGV--VVEVETLPEEGFVPDPERVRRAITPRTKALVV 170
Query: 201 G------TSCYSRNLEYA--------RLRKIADENGAYLMADMAHIS-GLVA 237
+ Y + + A ++DE +L+ + H S G VA
Sbjct: 171 NSPNNPTGAVYPKEVLEALARLAVEHDFYLVSDEIYEHLLYEGEHFSPGRVA 222
>2OGE-A nrPDB
Length = 399
Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats.
Identities = 27/133 (20%), Positives = 49/133 (36%), Gaps = 16/133 (12%)
Query: 104 YKLDPQCWGVNVQPYSGSPANFAVYTAL-VEPHGRIMGLDLPDGGHLTHGFMTDKKKISA 162
+ + V SG A L + P ++ +P +H ++ +SA
Sbjct: 72 FAAYCETDHA-VGVNSGMDALQLALRGLGIGPGDEVI---VP-----SHTYIASWLAVSA 122
Query: 163 TSIFFESMPYKVNPDTGYINYDQL-EENARLFHPKLIIAGTSCYSRNLEYARLRKIADEN 221
T + P V P + D L E A + ++ Y + LR++AD +
Sbjct: 123 TG----ATPVPVEPHEDHPTLDPLLVEKAITPRTRALLP-VHLYGHPADMDALRELADRH 177
Query: 222 GAYLMADMAHISG 234
G +++ D A G
Sbjct: 178 GLHIVEDAAQAHG 190
>5W70-A nrPDB
Length = 445
Score = 30.4 bits (67), Expect = 1.8, Method: Composition-based stats.
Identities = 38/177 (21%), Positives = 60/177 (33%), Gaps = 21/177 (11%)
Query: 99 RALQAYKLDPQCWGVNVQPYSGSPANFAVYTAL-VEPHGRIM--GLDLPDGGHLTHGFMT 155
RA AY P C V SG+ + A + ++ GL G G
Sbjct: 80 RAFAAYNGVPHC----VPAASGTASLMLALEACGIGAGDEVIVPGLSWVASGSTILG--- 132
Query: 156 DKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLR 215
++A IF + V+PDT ++ + +E +++ YS + L
Sbjct: 133 ----VNAVPIFCD-----VDPDTLCLSPEAVEAAITEHTRAIVVV--HLYSALADMDALS 181
Query: 216 KIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVTTTTHKTLRGCRAGMIFYRKG 272
IA+ +G L+ D A G GV + K L G + R
Sbjct: 182 AIAERHGLPLIEDCAQAHGATYRGVKVGALATAGTFSMQHSKVLTSGEGGAVITRDE 238
>1RVG-A nrPDB
Length = 305
Score = 30.4 bits (67), Expect = 1.9, Method: Composition-based stats.
Identities = 18/69 (26%), Positives = 26/69 (37%), Gaps = 14/69 (20%)
Query: 180 YINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
+I++ +LE ARL L++ G S L R R E G AAG
Sbjct: 188 FIDHARLERIARLVPAPLVLHGASAVPPEL-VERFRASGGEIGE-------------AAG 233
Query: 240 VVPSPFEHC 248
+ P +
Sbjct: 234 IHPEDIKKA 242
>5OFO-C nrPDB
Length = 871
Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNN- 71
DL ++ P+ D E+ I+ R + LI A++E L + N
Sbjct: 171 DLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIING 230
Query: 72 KYSEGYPGQR 81
+ EG G+R
Sbjct: 231 EVPEGLKGRR 240
>4CIU-A nrPDB
Length = 727
Score = 30.0 bits (66), Expect = 2.1, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNN- 71
DL ++ P+ D E+ I+ R + LI A++E L + N
Sbjct: 25 DLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIING 84
Query: 72 KYSEGYPGQR 81
+ EG G+R
Sbjct: 85 EVPEGLKGRR 94
>1JBK-A nrPDB
Length = 195
Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats.
Identities = 17/70 (24%), Positives = 28/70 (40%), Gaps = 1/70 (1%)
Query: 13 DLWSSHDKMLAQPLKDSDVEVYNIIKKESNRQRVGLELIASENFASRAVLEALGSCLNN- 71
DL ++ P+ D E+ I+ R + LI A++E L + N
Sbjct: 11 DLTERAEQGKLDPVIGRDEEIRRTIQVLQRRTKNNPVLIGEPGVGKTAIVEGLAQRIING 70
Query: 72 KYSEGYPGQR 81
+ EG G+R
Sbjct: 71 EVPEGLKGRR 80
>5O5C-A nrPDB
Length = 519
Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats.
Identities = 29/167 (17%), Positives = 62/167 (37%), Gaps = 29/167 (17%)
Query: 120 GSPANFAVYT-------ALVEPHGRIMGLDLPDGG--------HLTHGFMTDKKKISATS 164
G+ +N A P I LP L+H + +K ++
Sbjct: 170 GTQSNLMAMLLARDSWCAAHHPGHLIKHRGLPHDAAKWRVFTSKLSH--FSIQKSMAILG 227
Query: 165 IFFESMPYKVNPDTGY-INYDQLEE-----NARLFHPKLIIA--GTSCYSRNLEYARLRK 216
+ ++++ V+ D Y ++ D L++ + P ++A GT+ + + +
Sbjct: 228 LGYDAVI-PVDYDERYRMDVDCLKQEVQRCLQQGLIPVAVVATSGTTDFGSIDPLGAISE 286
Query: 217 IADENGAYLMADMAHISGLVAAGVVP---SPFEHCHVVTTTTHKTLR 260
+ +G ++ D A+ GL+ + + E VT HK+
Sbjct: 287 LCKHHGMWMHVDAAYGCGLLVSESHRPRLAGIEKADSVTVDYHKSFF 333
>2YWH-A nrPDB
Length = 600
Score = 29.6 bits (65), Expect = 2.8, Method: Composition-based stats.
Identities = 8/26 (30%), Positives = 14/26 (53%)
Query: 117 PYSGSPANFAVYTALVEPHGRIMGLD 142
PY G+ A ++ V+P +IM +
Sbjct: 204 PYRGAVAFVRIFDGEVKPGDKIMLMS 229
>6C9E-A nrPDB
Length = 422
Score = 29.6 bits (65), Expect = 2.9, Method: Composition-based stats.
Identities = 42/265 (15%), Positives = 79/265 (29%), Gaps = 32/265 (12%)
Query: 134 PHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEENARLF 193
P I+ + ++ M KK + P +N G + ++ E
Sbjct: 128 PDEEILITHMEHHSNIVPWQMVCKK----MGCKLQVAPISLN---GEVILEEFERKLNEN 180
Query: 194 HPKLIIAGTSCYSRNL-EYARLRKIADENGAYLMADMAHISGLVAAGVVPSPFEHCHVVT 252
+ I S + + K+A E GA ++ D A + + V C
Sbjct: 181 TKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLLDGAQATAHLIVDVQD---LDCDFYA 237
Query: 253 TTTHKTLRGCRAGMIFYRKGVKSVDPKTGKEILYNLESLINSAVFPGLQGGPHNHAIAGV 312
+ HK + G + + K +INS F + H
Sbjct: 238 FSGHK-MYGPTGIGVLWGKEELLN----SMTPYQGGGEMINSVSFEATEYAAIPHKFEAG 292
Query: 313 AVALKQAMT-------------LEFKVYQHQVVANCRALSEALTELGYKIVTGGSDNHLI 359
+ A+ Y+ Q++ EA+ GY I+ G + N +
Sbjct: 293 TPNIAGAIGLAAAIDYIWSLDLDAIAEYETQLLNYATKAIEAV--KGYNII-GTAANKVP 349
Query: 360 LVDLRSKGTDGGRAEKVLEACSIAC 384
++ +L++ IA
Sbjct: 350 IISFVHGKIHAHDIGTILDSEGIAI 374
>2FJK-A nrPDB
Length = 305
Score = 28.9 bits (63), Expect = 4.6, Method: Composition-based stats.
Identities = 15/69 (21%), Positives = 26/69 (37%), Gaps = 14/69 (20%)
Query: 180 YINYDQLEENARLFHPKLIIAGTSCYSRNLEYARLRKIADENGAYLMADMAHISGLVAAG 239
+I++ +L A+L L++ G S + L R R E G A+G
Sbjct: 188 FIDHPRLARIAKLVPAPLVLHGASAVPQEL-VERFRAAGGEIGE-------------ASG 233
Query: 240 VVPSPFEHC 248
+ P +
Sbjct: 234 IHPEDIKKA 242
>5X8P-8 nrPDB
Length = 370
Score = 28.1 bits (61), Expect = 9.0, Method: Composition-based stats.
Identities = 13/86 (15%), Positives = 35/86 (40%), Gaps = 12/86 (13%)
Query: 130 ALVEPHGRIMGLDLPDGGHLTHGFMTDKKKISATSIFFESMPYKVNPDTGYINYDQLEEN 189
+++P + + L ++ ++S ++ E P + + + +++ EE
Sbjct: 261 TVLQPGDTLKVMILSH--------DRERGRVSLSTKKLEPTPGDMIRNPKLV-FEKAEEM 311
Query: 190 ARLFHPKLIIAGTSCYSRNLEYARLR 215
A+ F + IA +R + R +
Sbjct: 312 AQTFRQR--IAQAEAMARA-DMLRFQ 334
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.309 0.134 0.379
Lambda K H
0.267 0.0414 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,863,347
Number of Sequences: 36641
Number of extensions: 842658
Number of successful extensions: 2335
Number of sequences better than 10.0: 69
Number of HSP's better than 10.0 without gapping: 51
Number of HSP's successfully gapped in prelim test: 48
Number of HSP's that attempted gapping in prelim test: 2109
Number of HSP's gapped (non-prelim): 105
length of query: 483
length of database: 10,336,785
effective HSP length: 101
effective length of query: 382
effective length of database: 6,636,044
effective search space: 2534968808
effective search space used: 2534968808
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.1 bits)
S2: 61 (28.1 bits)