BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P32929 (405 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5TSU-A nrPDB 833 0.0 4IYO-A nrPDB 403 e-113 1N8P-A nrPDB 384 e-107 4L0O-H nrPDB 382 e-106 6CJB-A nrPDB 370 e-103 5X5H-A nrPDB 342 2e-94 1IBJ-A nrPDB 324 4e-89 3VK2-A nrPDB 324 4e-89 3QI6-A nrPDB 323 9e-89 3MKJ-A nrPDB 322 2e-88 5DX5-A nrPDB 312 2e-85 1E5F-A nrPDB 301 3e-82 4U1T-A nrPDB 290 6e-79 1CS1-A nrPDB 288 2e-78 3AEO-A nrPDB 274 4e-74 1PFF-A nrPDB 265 2e-71 1I43-A nrPDB 245 2e-65 4KAM-A nrPDB 228 2e-60 5IJG-A nrPDB 223 1e-58 3NDN-A nrPDB 212 3e-55 2CTZ-A nrPDB 200 9e-52 2FQ6-A nrPDB 182 3e-46 4OC9-A nrPDB 178 4e-45 3RI6-A nrPDB 174 5e-44 2CB1-A nrPDB 162 2e-40 1V2E-A nrPDB 46 3e-05 3NYS-A nrPDB 40 0.002 3B46-A nrPDB 38 0.006 4M2J-A nrPDB 38 0.007 2Z61-A nrPDB 37 0.019 6F35-A nrPDB 35 0.046 3GPU-A nrPDB 35 0.064 1YIY-A nrPDB 33 0.15 3IF2-A nrPDB 33 0.19 1L1Z-A nrPDB 33 0.21 3JTX-A nrPDB 33 0.32 6F77-B nrPDB 32 0.42 3CAI-A nrPDB 32 0.57 1U08-A nrPDB 32 0.63 4R2N-A nrPDB 32 0.68 1GC4-A nrPDB 32 0.73 3FFH-A nrPDB 31 0.97 3G7Q-A nrPDB 31 1.0 1J32-A nrPDB 30 1.6 4NFY-A nrPDB 30 2.3 1D2F-A nrPDB 30 2.5 4I9T-A nrPDB 29 3.4 4WP0-A nrPDB 29 4.2 4AEE-A nrPDB 29 4.5 3FVS-A nrPDB 29 4.7 5W70-A nrPDB 28 5.4 2X5D-A nrPDB 28 5.9 1T3I-A nrPDB 28 7.6 4MY5-A nrPDB 28 7.9 1O4S-A nrPDB 28 8.2 >5TSU-A nrPDB Length = 422 Score = 833 bits (2153), Expect = 0.0, Method: Compositional matrix adjust. Identities = 401/404 (99%), Positives = 401/404 (99%) Query: 2 QEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYS 61 QEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGF YS Sbjct: 19 QEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFNYS 78 Query: 62 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYF 121 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTN YF Sbjct: 79 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNLYF 138 Query: 122 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD Sbjct: 139 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 198 Query: 182 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQN 241 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQN Sbjct: 199 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQN 258 Query: 242 SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHE 301 SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHE Sbjct: 259 SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHE 318 Query: 302 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLK 361 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLA SLGGFESLAELPAIMTHASVLK Sbjct: 319 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAVSLGGFESLAELPAIMTHASVLK 378 Query: 362 NDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS 405 NDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS Sbjct: 379 NDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS 422 >4IYO-A nrPDB Length = 397 Score = 403 bits (1035), Expect = e-113, Method: Compositional matrix adjust. Identities = 208/380 (54%), Positives = 265/380 (69%), Gaps = 6/380 (1%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAA 77 AT AIH GQ P+ T AV+PPI ++T+ Q +PG+H GFEYSR+ NPTR E+ VAA Sbjct: 17 LATLAIHGGQSPDPSTG-AVMPPIYATSTYAQSSPGEHQGFEYSRTHNPTRFAYERCVAA 75 Query: 78 LDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF-GLKISFVD 136 L+G AFASG+AAT T+ LL AG ++ MDD+YGGT R F +V GL SFVD Sbjct: 76 LEGGTRAFAFASGMAATSTVMELLDAGSHVVAMDDLYGGTFRLFERVRRRTAGLDFSFVD 135 Query: 137 CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQ 196 + +AAI +TK+VWIETPTNP K++DI A I KHG ++ VVDNTF SP Q Sbjct: 136 LTDPAAFKAAIRADTKMVWIETPTNPMLKLVDIAAIAVIARKHG-LLTVVDNTFASPMLQ 194 Query: 197 RPLALGADISMYSATKYMNGHSDVVMGLVSV--NCESLHNRLRFLQNSLGAVPSPIDCYL 254 RPL+LGAD+ ++SATKY+NGHSD+V G+ V N E L ++ FLQNS+G V P D +L Sbjct: 195 RPLSLGADLVVHSATKYLNGHSDMVGGIAVVGDNAE-LAEQMAFLQNSIGGVQGPFDSFL 253 Query: 255 CNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMV 314 RGLKTL +RM H +N +A+AQ+LE++P +EKVIYPGL SHPQH L KRQ +G G+V Sbjct: 254 ALRGLKTLPLRMRAHCENALALAQWLETHPAIEKVIYPGLASHPQHVLAKRQMSGFGGIV 313 Query: 315 TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 374 + +KG A+ F + +LFTLAESLGG ESL PA+MTHAS+ R+ LGISD L+ Sbjct: 314 SIVLKGGFDAAKRFCEKTELFTLAESLGGVESLVNHPAVMTHASIPVARREQLGISDALV 373 Query: 375 RLSVGLEDEEDLLEDLDQAL 394 RLSVG+ED DL DL++AL Sbjct: 374 RLSVGIEDLGDLRGDLERAL 393 >1N8P-A nrPDB Length = 393 Score = 384 bits (987), Expect = e-107, Method: Compositional matrix adjust. Identities = 200/387 (51%), Positives = 267/387 (68%), Gaps = 10/387 (2%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSG-FEYSRSGNPTRNCLEKAVA 76 FAT+AIH G+ + S V+ PISLSTTFKQ +P G +EYSRS NP R LE+AVA Sbjct: 8 FATKAIHAGEHVDVHGS--VIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVA 65 Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD 136 AL+ A+Y LAF+SG A T TI L G + + DVYGGT+RYF +VA+ G++ SF + Sbjct: 66 ALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTN 125 Query: 137 CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHG---DIILVVDNTFMSP 193 + L I TKLVWIETPTNPT KV DI+ A ++ KH D+ILVVDNTF+SP Sbjct: 126 -DLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNTFLSP 184 Query: 194 YFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCY 253 Y PL GADI ++SATKY+NGHSDVV+G+++ N + L+ RL+FLQN++GA+PSP D + Sbjct: 185 YISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAW 244 Query: 254 LCNRGLKTLHVRMEKHFKNGMAVAQFLESNPW-VEKVIYPGLPSHPQHELVKRQCTGCT- 311 L +RGLKTLH+R+ + + +A+FL ++ V V YPGL +HP +++V +Q Sbjct: 245 LTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALG 304 Query: 312 -GMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGIS 370 GM++F IKG + A F + +LFTLAESLGG ESL E+PA+MTH + K R+ G+ Sbjct: 305 GGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVF 364 Query: 371 DTLIRLSVGLEDEEDLLEDLDQALKAA 397 D L+R+SVG+ED +DLLED+ QALK A Sbjct: 365 DDLVRISVGIEDTDDLLEDIKQALKQA 391 >4L0O-H nrPDB Length = 388 Score = 382 bits (982), Expect = e-106, Method: Compositional matrix adjust. Identities = 191/375 (50%), Positives = 255/375 (68%), Gaps = 3/375 (0%) Query: 20 TQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALD 79 T+ IH G E T+ AV PI ++T++Q A G+H G+EYSRSGNPTR LE+ +A L+ Sbjct: 5 TKLIH-GGISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIADLE 63 Query: 80 GAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSK 139 G AFASGLA + LL++GD ++ DDVYGGT R F QV + GL + +D S Sbjct: 64 GGVKGFAFASGLAGIHAVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIIDTSD 123 Query: 140 IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPL 199 I ++ AI P TK +++ETP+NP K+ D+ CA + HG ++ +VDNTF +PY+Q PL Sbjct: 124 ISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHG-LLTIVDNTFATPYYQNPL 182 Query: 200 ALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGL 259 LGADI +S TKY+ GHSDVV GLV+ N E+L + F QN++G V P D +L RG+ Sbjct: 183 LLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQRGI 242 Query: 260 KTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIK 319 KTL +RME H KN + VA+FLE +P VE+V YPGLP+HP +EL K+Q G +GM++F +K Sbjct: 243 KTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSGMLSFTLK 302 Query: 320 GTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVG 379 A F+++LKLF L ESLGG ESL +PA MTHA + K R+ GI D L+RLSVG Sbjct: 303 ND-SEAVAFVESLKLFILGESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVRLSVG 361 Query: 380 LEDEEDLLEDLDQAL 394 +E E+DLLEDL+QA Sbjct: 362 IEHEQDLLEDLEQAF 376 >6CJB-A nrPDB Length = 391 Score = 370 bits (950), Expect = e-103, Method: Compositional matrix adjust. Identities = 199/380 (52%), Positives = 263/380 (69%), Gaps = 4/380 (1%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVA 76 HF T+AIH GQ+P + T AV+ PI ++T+KQ APG+H G+EYSR+ NPTR E +A Sbjct: 13 HFDTRAIHAGQEPCKSTG-AVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIA 71 Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF-GLKISFV 135 +L+ + AFASG+AA T+ LL +GD ++ MDD+YGGT R F +V + L SF+ Sbjct: 72 SLESGQKGFAFASGMAAINTVIDLLGSGDHVVAMDDLYGGTFRLFDKVKTRTSNLSFSFI 131 Query: 136 DCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF 195 D S + +EAAITP+TKL+W+ETP+NP K+ ++ A I K+ ++I V DNTF +P+ Sbjct: 132 DMSVPENIEAAITPKTKLLWLETPSNPMLKLANLRKIAAIAKKY-NLITVADNTFATPWI 190 Query: 196 QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCES-LHNRLRFLQNSLGAVPSPIDCYL 254 QRPL LG DI ++SATKY+NGHSDVV G+V V S L +++ FLQNS GAV P D +L Sbjct: 191 QRPLELGFDIVLHSATKYLNGHSDVVSGVVVVGDNSVLSDKIAFLQNSCGAVAGPFDSFL 250 Query: 255 CNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMV 314 R LKTL VRM++H +N +A +L S+P +EKVIYPGL SHPQ+ L K Q GM+ Sbjct: 251 VLRSLKTLSVRMQRHCENANHLANWLSSHPKIEKVIYPGLKSHPQYSLAKEQMNNFGGMI 310 Query: 315 TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 374 + +KG+L+ A+ FL +LFTLAESLGG ESL E PAIMTHAS+ R LGI D I Sbjct: 311 SLVLKGSLEDAKRFLARCELFTLAESLGGVESLIEHPAIMTHASIPVEQRKALGIEDGFI 370 Query: 375 RLSVGLEDEEDLLEDLDQAL 394 RLSVG+E +DL DL+ AL Sbjct: 371 RLSVGIEHIDDLRADLEHAL 390 >5X5H-A nrPDB Length = 392 Score = 342 bits (876), Expect = 2e-94, Method: Compositional matrix adjust. Identities = 181/387 (46%), Positives = 245/387 (63%), Gaps = 7/387 (1%) Query: 11 FLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQ-HSGFEYSRSGNPTRN 69 F P+ Q F+T +IH G +P+ + ++ PI STTF Q AP + G+EY+R GNPT Sbjct: 3 FDPNTQGFSTASIHAGYEPDDYYG-SINTPIYASTTFAQNAPNELRKGYEYTRVGNPTIV 61 Query: 70 CLEKAVAALDGAKYCLAFASGLAAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 LE+ VAAL+GAKY AF+SG+AAT + +LK GD I+ +D YGGT R V + + Sbjct: 62 ALEQTVAALEGAKYGRAFSSGMAATDILFRIILKPGDHIVLGNDAYGGTYRLIDTVFTAW 121 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 G++ + VD S ++ ++AAI TKL+W+ETPTNP + DIE A + + LVVDN Sbjct: 122 GVEYTVVDTSVVEEVKAAIKDNTKLIWVETPTNPALGITDIEAVAKLTEGT-NAKLVVDN 180 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPS 248 TF SPY Q+PL LGA ++S TKY+ GHSDVV GLV N + + L F+Q +G +PS Sbjct: 181 TFASPYLQQPLKLGAHAVLHSTTKYIGGHSDVVGGLVVTNDQEMDEELLFMQGGIGPIPS 240 Query: 249 PIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCT 308 D YL RGLKTL VRM++H N +A+FL+S P V V+YPGL +HP HE+ +Q Sbjct: 241 VFDAYLTARGLKTLAVRMDRHCDNAEKIAEFLDSRPEVSTVLYPGLKNHPGHEVAAKQMK 300 Query: 309 GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLG 368 GM++ G + A+ F + KL LAESLGG ESL E PA MTH S + L Sbjct: 301 RFGGMISVRFAGGEEAAKKFCTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQ---LE 357 Query: 369 ISDTLIRLSVGLEDEEDLLEDLDQALK 395 + L+R+S+G+ED EDLL D++QAL Sbjct: 358 VPRDLVRISIGIEDIEDLLADVEQALN 384 >1IBJ-A nrPDB Length = 464 Score = 324 bits (831), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 158/360 (43%), Positives = 235/360 (65%), Gaps = 2/360 (0%) Query: 36 AVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATV 95 A+ P+ + TFKQ + ++ ++Y+RSGNPTR+ LE +A LD A F SG+AA Sbjct: 103 AMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKLDKADRAFCFTSGMAALS 162 Query: 96 TITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVW 155 +THL+K G++I+ DDVYGG++R QV G+ + V+ +K+ + AAI P+TKLVW Sbjct: 163 AVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTTKLDEVAAAIGPQTKLVW 222 Query: 156 IETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMN 215 +E+PTNP Q++ DI + + H G ++L VDN+ MSP RPL LGADI M+SATK++ Sbjct: 223 LESPTNPRQQISDIRKISEMAHAQGALVL-VDNSIMSPVLSRPLELGADIVMHSATKFIA 281 Query: 216 GHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMA 275 GHSDV+ G+++V E L + FLQNS G+ +P DC+LC RG+KT+ +R+EK +N Sbjct: 282 GHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRGIKTMALRIEKQQENARK 341 Query: 276 VAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLF 335 +A +L S+P V+KV Y GLP HP H L Q G G V +I G++ ++ ++ K F Sbjct: 342 IAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGA-GSVFSFITGSVALSKHLVETTKYF 400 Query: 336 TLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 395 ++A S G +SL +P M+HAS+ R+ G+++ L+R+S G+ED +DL+ DLD A K Sbjct: 401 SIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISAGIEDVDDLISDLDIAFK 460 >3VK2-A nrPDB Length = 398 Score = 324 bits (831), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 177/391 (45%), Positives = 252/391 (64%), Gaps = 14/391 (3%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGAP---GQHSGFEYSRSGNPTRN 69 FAT+AIH G DP+ A+VPP+ + TF + GA G+ +G YSR NPT N Sbjct: 10 FATRAIHHGYDPQDHGG-ALVPPVYQTATFTFPTVEYGAACFAGEQAGHFYSRISNPTLN 68 Query: 70 CLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 LE +A+L+G + LA ASG+ A T T+ LL+ GD+++ + +YG T + EF Sbjct: 69 LLEARMASLEGGEAGLALASGMGAITSTLWTLLRPGDEVLLGNTLYGHTFAFLHHGIGEF 128 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 G+K+ VD + ++ LEAA+TP T++++ E+P NP + DI G A I KHG + VVDN Sbjct: 129 GVKLRHVDMADLQALEAAMTPATRVIYFESPANPNMHMADIAGVAKIARKHGATV-VVDN 187 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRF--LQNSLGAV 246 T+ +PY QRPL LGAD+ ++SATKY++GH D+ G+V V ++L +R+R L++ GAV Sbjct: 188 TYCTPYLQRPLELGADLVVHSATKYLSGHGDITAGIV-VGSQALVDRIRLQGLKDMTGAV 246 Query: 247 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQ 306 SP D L RG+KTL++RM++H N +A+FL P VE + YPGL S PQ+ L ++Q Sbjct: 247 LSPHDAALLMRGIKTLNLRMDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLARQQ 306 Query: 307 CTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDV 366 + GM+ F +KG + F+ L+LF+ A SLG ESLA+ PA MTH+S +R Sbjct: 307 MSQPGGMIAFELKGGIGAGRRFMNALQLFSRAVSLGDAESLAQHPASMTHSSYTPEERAH 366 Query: 367 LGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397 GIS+ L+RLSVGLED +DLL D+ QALKA+ Sbjct: 367 YGISEGLVRLSVGLEDIDDLLADVQQALKAS 397 >3QI6-A nrPDB Length = 392 Score = 323 bits (828), Expect = 9e-89, Method: Compositional matrix adjust. Identities = 179/383 (46%), Positives = 237/383 (61%), Gaps = 7/383 (1%) Query: 14 HFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQ-GAPGQHSGFEYSRSGNPTRNCLE 72 F AT+AIH G P+ T AV PI S+TF Q G G G+EY+R+GNPTR LE Sbjct: 14 RFAGLATRAIHSGYRPDPATG-AVNAPIYASSTFAQDGVGGLRGGYEYARTGNPTRTALE 72 Query: 73 KAVAALDGAKYCLAFASGLAAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLK 131 A+AA++ A + AF+SG+AA + +L+ GD ++ DD YGGT R +V + + ++ Sbjct: 73 AALAAVEDAAFGRAFSSGMAAADCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTGWNVE 132 Query: 132 ISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFM 191 + V + + + AAI P T+L+W+ETPTNP + DI G A + +LV DNTF Sbjct: 133 YTPVALADLDAVRAAIRPTTRLIWVETPTNPLLSIADIAGIAQLGADSSAKVLV-DNTFA 191 Query: 192 SPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPID 251 SP Q+PL+LGAD+ ++S TKY+ GHSDVV G + N E L FLQN GAVP P D Sbjct: 192 SPALQQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAGAVPGPFD 251 Query: 252 CYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCT 311 YL RGLKTL +RM++H +N AVA+FL +P + V+YPGLPSHP H + RQ G Sbjct: 252 AYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAARQMRGFG 311 Query: 312 GMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISD 371 GMV+ ++ AE +F LAESLG ESL E P+ MTHAS + L + D Sbjct: 312 GMVSVRMRAGRTAAEQLCAKTNIFILAESLGSVESLIEHPSAMTHASTAGSQ---LEVPD 368 Query: 372 TLIRLSVGLEDEEDLLEDLDQAL 394 L+RLSVG+ED DLL+DL QAL Sbjct: 369 DLVRLSVGIEDVADLLDDLKQAL 391 >3MKJ-A nrPDB Length = 398 Score = 322 bits (826), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 176/391 (45%), Positives = 255/391 (65%), Gaps = 14/391 (3%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGAPG---QHSGFEYSRSGNPTRN 69 F TQ +H GQ P+ T A+ PI ++TF +QGA + SG+ Y+R GNPT + Sbjct: 9 FNTQIVHAGQQPDPSTG-ALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGNPTTD 67 Query: 70 CLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 LEK +A L+ + LA ASG++A T T+ L + GD I+ +YG T+ + +F Sbjct: 68 ALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLSHSMPKF 127 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 G+ +SFVD +K + + AA+ PETK+V+IETP NPT ++DIE A I H+ G +LVVDN Sbjct: 128 GINVSFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQG-ALLVVDN 186 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRF--LQNSLGAV 246 TFMSPY Q+PL LGADI ++S TKY+NGH DV+ G++ V + ++ RF L++ G Sbjct: 187 TFMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGII-VGKQEFIDQARFVGLKDITGGC 245 Query: 247 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQ 306 SP + +L RG+KTL +RME+H +N + +A+FLE +P + +V YPGL SHPQ+EL +RQ Sbjct: 246 MSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELGQRQ 305 Query: 307 CTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDV 366 + G+++F I G L+ + +++L LA SLG E+L + PA MTH+ V +R Sbjct: 306 MSLPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEERLK 365 Query: 367 LGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397 GI+D LIRLSVGLED ED++ DL+ A++ A Sbjct: 366 AGITDGLIRLSVGLEDPEDIINDLEHAIRKA 396 >5DX5-A nrPDB Length = 400 Score = 312 bits (799), Expect = 2e-85, Method: Compositional matrix adjust. Identities = 170/390 (43%), Positives = 249/390 (63%), Gaps = 16/390 (4%) Query: 18 FATQAIHVGQ-DPEQWTSRAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTR 68 FAT+AIH G +Q+ S A PI ++TF +QG G+ SG+ YSR GNPT Sbjct: 9 FATKAIHGGHIGDKQFGSLAT--PIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTS 66 Query: 69 NCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 +E +A L+G + + ASG+ A ++ LK+GD ++ D +YG T + Sbjct: 67 TEVENKLALLEGGEAAVVAASGMGAIAASLWSALKSGDHVVASDTLYGCTFALLNHGLTR 126 Query: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHK-HGDIILVV 186 +G++++FVD S + ++ A+ P TK+V++ETP NPT KV DI +++VH+ + + + V Sbjct: 127 YGVEVTFVDVSNLDEVKNALKPNTKVVYLETPANPTLKVTDIRKISNMVHESNKECFVFV 186 Query: 187 DNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRF--LQNSLG 244 DNTF +PY QRPL LGAD+ ++SATKY+NGH DV+ G +V E N+++ +++ G Sbjct: 187 DNTFCTPYIQRPLELGADVVVHSATKYLNGHGDVIAGF-AVGKEEFINQVKLFGIKDMTG 245 Query: 245 AVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVK 304 +V P + +L RG+KTL +RMEKH KN M VA+FLES+P VEKV YPGL S ++L + Sbjct: 246 SVTGPFESFLIIRGMKTLQLRMEKHCKNAMEVAKFLESHPAVEKVYYPGLESFKYYQLAR 305 Query: 305 RQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDR 364 Q M++F +KG ++ +I + N+KL TLA SLG E+L + PA MTH+ +R Sbjct: 306 EQMKLPGAMISFELKGGVEEGKIVMNNVKLATLAVSLGDSETLIQHPASMTHSPYTAEER 365 Query: 365 DVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394 GISD L+RLSVGLED ED+++DL QAL Sbjct: 366 KAAGISDGLVRLSVGLEDAEDIIDDLKQAL 395 >1E5F-A nrPDB Length = 404 Score = 301 bits (771), Expect = 3e-82, Method: Compositional matrix adjust. Identities = 161/388 (41%), Positives = 239/388 (61%), Gaps = 12/388 (3%) Query: 19 ATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRNC 70 AT IH +Q+ A +PPI ++TF +QG GQ SG+ Y+R GNPT + Sbjct: 9 ATACIHANPQKDQFG--AAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVSN 66 Query: 71 LEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFG 129 LE +A L+ + C+A +SG+ A T+ +LKAGD +I + +YG T+ F ++FG Sbjct: 67 LEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKFG 126 Query: 130 LKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNT 189 +++ F++ + ++ + P TK+V+ ETP NPT K+ID+E H ++++ DNT Sbjct: 127 IQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHSQEGVLVIADNT 186 Query: 190 FMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGAVPS 248 F SP P+ G D+ ++SATKY+NGH+DVV GL+ + L R+ +++ G+V S Sbjct: 187 FCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDITGSVIS 246 Query: 249 PIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCT 308 P D +L RGL TL++RM+ +N M VA++L+S+P VEKV YPG H H++ K+Q Sbjct: 247 PHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQMR 306 Query: 309 GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLG 368 M+TF +K + A+ L NLKL TLA SLGG ESL + PA MTHA V K +R+ G Sbjct: 307 MYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAAG 366 Query: 369 ISDTLIRLSVGLEDEEDLLEDLDQALKA 396 I+D +IRLSVG+ED ++L+ D Q L A Sbjct: 367 ITDGMIRLSVGIEDADELIADFKQGLDA 394 >4U1T-A nrPDB Length = 389 Score = 290 bits (743), Expect = 6e-79, Method: Compositional matrix adjust. Identities = 160/380 (42%), Positives = 226/380 (59%), Gaps = 9/380 (2%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVA 76 F T+ +H G+ P T VVPPI +STT+++ A + F Y R NPTR LE+ +A Sbjct: 5 RFDTRLVHGGRRPSAGTGD-VVPPIHVSTTYERRAQDEPRYF-YGRGENPTREELEECLA 62 Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD 136 L+ A + F+SG AA T+ L++ G ++ DDVY GT+ F +A+ G+++ + D Sbjct: 63 GLERAPFATVFSSGQAAAATLLSLVRPGQCVVSTDDVYAGTDGLF-DLAARQGVRVRYAD 121 Query: 137 CSKIKLLEAAIT-PETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF 195 + + + AA+ P+ LVWIETPTNP V+D+ + H+ G + VVDNTF SP Sbjct: 122 LTTPEGIAAALAEPDLALVWIETPTNPLLTVVDVAEVSRRAHERGARV-VVDNTFASPVL 180 Query: 196 QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLC 255 Q+PLALGAD+S+YS TK + GH+DV+ G + LH +R + + G VP +DC+L Sbjct: 181 QQPLALGADVSLYSTTKSIAGHADVLGGALVYRDADLHAAVRAYRTTAGNVPGALDCFLV 240 Query: 256 NRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVT 315 RGL TL +R+ + + + L ++P V V YPGLP HPQH +VK Q + +V+ Sbjct: 241 RRGLHTLSLRVHRQVATARVLVERLRASPVVGAVHYPGLPEHPQHAVVKAQMSAPGAIVS 300 Query: 316 F-YIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 374 F Y+ G AE L LFT SLGG SL E PA+MTH + R GI ++LI Sbjct: 301 FDYLGGP---AERLLDRFTLFTCGVSLGGVHSLVECPALMTHRPLSAEARARRGIGESLI 357 Query: 375 RLSVGLEDEEDLLEDLDQAL 394 RLSVG+ED +DL EDL +AL Sbjct: 358 RLSVGIEDPQDLAEDLSRAL 377 >1CS1-A nrPDB Length = 386 Score = 288 bits (738), Expect = 2e-78, Method: Compositional matrix adjust. Identities = 159/382 (41%), Positives = 227/382 (59%), Gaps = 5/382 (1%) Query: 19 ATQAIHVG-QDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAA 77 AT A+ G D EQ+ VVPPI LS+T+ + +YSR GNPTR+ +++A+A Sbjct: 6 ATIAVRSGLNDDEQYG--CVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAE 63 Query: 78 LDGAKYCLAFASGLAAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD 136 L+G + +G++A + T LK GD ++ D YGG+ R F +A ++ FVD Sbjct: 64 LEGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVD 123 Query: 137 CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQ 196 + L AA+ + KLV +E+P+NP +V+DI H+ + G + VVDNTF+SP Q Sbjct: 124 QGDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVG-AVSVVDNTFLSPALQ 182 Query: 197 RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 256 PLALGAD+ ++S TKY+NGHSDVV G+V + L + N++G D YL Sbjct: 183 NPLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLL 242 Query: 257 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTF 316 RGL+TL RME +N A+ ++L++ P V+K+ +P LP + HE+ RQ G M++F Sbjct: 243 RGLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSF 302 Query: 317 YIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRL 376 + G Q FL L LFTLAESLGG ESL A MTHA + R GIS+TL+R+ Sbjct: 303 ELDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRI 362 Query: 377 SVGLEDEEDLLEDLDQALKAAH 398 S G+ED EDL+ DL+ +AA+ Sbjct: 363 STGIEDGEDLIADLENGFRAAN 384 >3AEO-A nrPDB Length = 389 Score = 274 bits (701), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 152/365 (41%), Positives = 229/365 (62%), Gaps = 11/365 (3%) Query: 40 PISLSTTF-----KQGAP---GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGL 91 PI ++TF +QGA G+ G YSR GNPT E+ V +++GA AF SG+ Sbjct: 25 PIFQTSTFCFDSTQQGADLFMGKGEGHIYSRLGNPTVEQFEEMVCSIEGAAGSAAFGSGM 84 Query: 92 AATVTIT-HLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPE 150 A + T L+ GD +I D +YG T F FG+++ +D S ++ ++AA P Sbjct: 85 GAISSSTLAFLQKGDHLIAGDTLYGCTVSLFTHWLPRFGIEVDLIDTSDVEKVKAAWKPN 144 Query: 151 TKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSA 210 TK+V++E+P NPT KV DI+G A + H+ G LVVD TF SP F +PL LGADI+++S Sbjct: 145 TKMVYLESPANPTCKVSDIKGIAVVCHERG-ARLVVDATFTSPCFLKPLELGADIALHSV 203 Query: 211 TKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHF 270 +KY+NGH DV+ G+ S ++F + G++ +P+D +LC RG+KTL +RM+ H Sbjct: 204 SKYINGHGDVIGGVSSAKTAEDIATIKFYRKDAGSLMAPMDAFLCARGMKTLPIRMQIHM 263 Query: 271 KNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLK 330 +NG+ VA+FLE + + KV +PGL S P H++ K+Q TG F +K + + A+ ++ Sbjct: 264 ENGLKVAKFLEQHEKIVKVNHPGLESFPGHDIAKKQMTGYGSTFLFEMK-SFEAAKKLME 322 Query: 331 NLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDL 390 +LK+ TLA SLG ++L E PA MTHA+V +N GI+ L+R+SVG+E+ +D++ DL Sbjct: 323 HLKVCTLAVSLGCVDTLIEHPASMTHAAVPENIMRKQGITPELVRISVGIENVDDIIADL 382 Query: 391 DQALK 395 QAL+ Sbjct: 383 KQALE 387 >1PFF-A nrPDB Length = 331 Score = 265 bits (677), Expect = 2e-71, Method: Compositional matrix adjust. Identities = 143/328 (43%), Positives = 206/328 (62%), Gaps = 3/328 (0%) Query: 69 NCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 + LE +A L+ A+ C A ASG+ A ++ LKAGD +I D +YG T+ F + Sbjct: 1 SALEGKIAKLEHAEACAATASGMGAIAASVWTFLKAGDHLISDDCLYGCTHALFEHQLRK 60 Query: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187 FG+++ F+D + +E + P T++V+ ETP NPT KVIDIE K DI+++VD Sbjct: 61 FGVEVDFIDMAVPGNIEKHLKPNTRIVYFETPANPTLKVIDIEDAVKQARKQKDILVIVD 120 Query: 188 NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGAV 246 NTF SP PL LG DI ++SATKY+NGH+DVV GLV + + + + +++ GA+ Sbjct: 121 NTFASPILTNPLDLGVDIVVHSATKYINGHTDVVAGLVCSRADIIAKVKSQGIKDITGAI 180 Query: 247 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQ 306 SP D +L RG TL +R+++ +N VA+FL + V+KV YPGLP HP HE+ K+Q Sbjct: 181 ISPHDAWLITRGTLTLDMRVKRAAENAQKVAEFLHEHKAVKKVYYPGLPDHPGHEIAKKQ 240 Query: 307 CTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDV 366 M+ F + G L+ A+ L N + +LA SLGG ESL + PA MTHA V K +R+ Sbjct: 241 MKMFGSMIAFDVDG-LEKAKKVLDNCHVVSLAVSLGGPESLIQHPASMTHAGVPKEEREA 299 Query: 367 LGISDTLIRLSVGLEDEEDLLEDLDQAL 394 G++D LIRLSVG E+ +D+++DL QAL Sbjct: 300 AGLTDNLIRLSVGCENVQDIIDDLKQAL 327 >1I43-A nrPDB Length = 445 Score = 245 bits (626), Expect = 2e-65, Method: Compositional matrix adjust. Identities = 133/345 (38%), Positives = 210/345 (60%), Gaps = 4/345 (1%) Query: 54 QHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGL-AATVTITHLLKAGDQIICMDD 112 + + FEY R GNPT LE+ ++AL+GA+ L ASG+ A+TV + L+ AG I+ D Sbjct: 102 RRASFEYGRYGNPTTVVLEEKISALEGAESTLLMASGMCASTVMLLALVPAGGHIVTTTD 161 Query: 113 VYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAIT-PETKLVWIETPTNPTQKVIDIEG 171 Y T + + + G+ + +D + + LE A+ + L + E+PTNP + +DIE Sbjct: 162 CYRKTRIFIETILPKMGITATVIDPADVGALELALNQKKVNLFFTESPTNPFLRCVDIEL 221 Query: 172 CAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCES 231 + + H+ G ++ +D TF +P Q+ LALGAD+ ++SATK++ GH+DV+ G +S + Sbjct: 222 VSKLCHEKGALV-CIDGTFATPLNQKALALGADLVLHSATKFLGGHNDVLAGCISGPLK- 279 Query: 232 LHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIY 291 L + +R L + LG +P YL RG+KTLH+R+++ + +A+ LE++P V V Y Sbjct: 280 LVSEIRNLHHILGGALNPNAAYLIIRGMKTLHLRVQQQNSTALRMAEILEAHPKVRHVYY 339 Query: 292 PGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELP 351 PGL SHP+H + K+Q TG G V+F + G L F+ LK+ +A S GG ES+ + P Sbjct: 340 PGLQSHPEHHIAKKQMTGFGGAVSFEVDGDLLTTAKFVDALKIPYIAPSFGGCESIVDQP 399 Query: 352 AIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKA 396 AIM++ + ++DR GI D L+R S G+ED +DL D+ QAL + Sbjct: 400 AIMSYWDLSQSDRAKYGIMDNLVRFSFGVEDFDDLKADILQALDS 444 >4KAM-A nrPDB Length = 453 Score = 228 bits (582), Expect = 2e-60, Method: Compositional matrix adjust. Identities = 147/426 (34%), Positives = 220/426 (51%), Gaps = 43/426 (10%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPI-SLSTTFKQGAPG------QHSGFEYSRSGNPTRNC 70 F T+ IH GQ P+ T+ +P + S TF+ A + G Y+R GNPT + Sbjct: 22 FETKQIHAGQQPDSATNARALPIYQTTSYTFENTAHAAALFGLEVPGNIYTRLGNPTTDV 81 Query: 71 LEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFG 129 +E+ +AAL+G L +SG AA T I +L AGD I+ +YGGT F ++ G Sbjct: 82 VEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKLG 141 Query: 130 LKISFVD-CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 +++SFVD + +AA+ P TK + ET +NP ++D G A + H++G I L+VDN Sbjct: 142 IEVSFVDDPDNLDSWQAAVRPNTKAFFGETISNPQIDLLDTPGVAEVAHRNG-IPLIVDN 200 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV----------------------- 225 T +PY RP GADI ++SATKY+ GH + G++ Sbjct: 201 TIATPYLIRPFTQGADIVVHSATKYLGGHGAAIAGVIVDGGTFDWTQGRFPEFTTPDPSY 260 Query: 226 --------SVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVA 277 +L R++ L++ LG+ SP + +L +GL+TL +R+E+H N VA Sbjct: 261 HGVVFAELGAPAYALKARVQLLRD-LGSAASPFNAFLVAQGLETLSLRIERHVSNAQRVA 319 Query: 278 QFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNLKLFT 336 +FL V V Y GLP P HE K+ TG V +F + G ++ + F+ LKL + Sbjct: 320 EFLADREDVVTVNYAGLPGSPWHERAKKLSPKGTGAVLSFELAGGVEAGKAFVNALKLHS 379 Query: 337 LAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKA 396 ++G SL PA THA + ++ G+S L+RL+VG+E ED+L DL+ A Sbjct: 380 HVANIGDVRSLVIHPASTTHAQLSPAEQLSTGVSPGLVRLAVGIEGIEDILADLELGFAA 439 Query: 397 AHPPSG 402 A SG Sbjct: 440 ARKFSG 445 >5IJG-A nrPDB Length = 427 Score = 223 bits (568), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 140/408 (34%), Positives = 216/408 (52%), Gaps = 38/408 (9%) Query: 14 HFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTF------------------KQGAPGQH 55 H H TQ ++ G D E + AV PP+ L++TF K+ G Sbjct: 14 HLLHPETQMLNYGYDSE-LSEGAVKPPVFLTSTFVFKTAEDGRDFFDFVSGRKEPPAGVG 72 Query: 56 SGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVY 114 +G YSR +P +E +A +GA+ F+SG++A T+ ++ GD I+ +Y Sbjct: 73 AGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIATTLFAFVRPGDVILHSQPLY 132 Query: 115 GGTNRYFRQVASEFGLK-ISFVDCSKIKLLEAAITP-----ETKLVWIETPTNPTQKVID 168 GGT + FG++ ++F D +E A ++ IETP NPT ++D Sbjct: 133 GGTETLLAKTFFNFGVEAVAFADGVHEATIEKAAEEALAKGRVSVILIETPANPTNSIVD 192 Query: 169 IEGCAHIVHK-----HGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMG 223 + + K ++ DNT + P FQ+PL GAD+S+YS TKY+ GHSD++ G Sbjct: 193 VAAVRRVAEKIEARQGSRPVIACDNTLLGPVFQKPLDHGADLSVYSLTKYVGGHSDLIAG 252 Query: 224 LVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESN 283 V + +S+ +++ L+ ++G P C++ R L+TL +RME+ N A+A+FL ++ Sbjct: 253 AV-LGAKSVVRQVKALRGAIGTQLDPHSCWMLGRSLETLGLRMERADSNARAIAEFLRNH 311 Query: 284 PWVEKVIYPGLPSHPQHE----LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAE 339 P VEK+ Y LP + L KRQCTG +F IKG A FL L++ LA Sbjct: 312 PKVEKLHY--LPFADERSDIAALFKRQCTGAGSTFSFDIKGGQAAAFRFLNALQILKLAV 369 Query: 340 SLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLL 387 SLGG ESLA PA MTH+ V + R+ +G+ ++ IRLS+G+E +DL+ Sbjct: 370 SLGGTESLASHPAAMTHSGVPVDVRERIGVLESTIRLSIGIEHPDDLI 417 >3NDN-A nrPDB Length = 414 Score = 212 bits (539), Expect = 3e-55, Method: Compositional matrix adjust. Identities = 117/347 (33%), Positives = 194/347 (55%), Gaps = 6/347 (1%) Query: 53 GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMD 111 G+ + YSR GNPT + E+ + ++GA A ASG+AA T + LL AGD+++ Sbjct: 68 GELDHYVYSRYGNPTVSVFEERLRLIEGAPAAFATASGMAAVFTSLGALLGAGDRLVAAR 127 Query: 112 DVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEG 171 ++G ++ +G++ FVD + E A++ T+ V+ ETP+NP Q ++DI Sbjct: 128 SLFGSCFVVCSEILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFETPSNPMQSLVDIAA 187 Query: 172 CAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCES 231 + H G + V+DN F +P Q+ LG D+ +YS TK+++G V+ G + + E Sbjct: 188 VTELAHAAGAKV-VLDNVFATPLLQQGFPLGVDVVVYSGTKHIDGQGRVLGGAILGDREY 246 Query: 232 LHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIY 291 + ++ L G S + ++ +GL+TL +R++ + +A+FL +P V V Y Sbjct: 247 IDGPVQKLMRHTGPAMSAFNAWVLLKGLETLAIRVQHSNASAQRIAEFLNGHPSVRWVRY 306 Query: 292 PGLPSHPQHELVKRQCTGCTGMVTFYI----KGTLQHAEIFLKNLKLFTLAESLGGFESL 347 P LPSHPQ++L KRQ +G +VTF + Q A L ++L ++ +LG +SL Sbjct: 307 PYLPSHPQYDLAKRQMSGGGTVVTFALDCPEDVAKQRAFEVLDKMRLIDISNNLGDAKSL 366 Query: 348 AELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394 PA TH ++ R +G+ D ++R+SVGLED +DL+ D+D+AL Sbjct: 367 VTHPATTTHRAMGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRAL 413 >2CTZ-A nrPDB Length = 421 Score = 200 bits (509), Expect = 9e-52, Method: Compositional matrix adjust. Identities = 141/422 (33%), Positives = 212/422 (50%), Gaps = 49/422 (11%) Query: 18 FATQAIHVGQDPEQWT-SRAVVPPISLSTTFKQGAPGQHS---------GFEYSRSGNPT 67 F T +H G +PE T SR V PI +T++ +P +H+ G YSR NPT Sbjct: 3 FETLQLHAGYEPEPTTLSRQV--PIYPTTSYVFKSP-EHAANLFALKEFGNIYSRIMNPT 59 Query: 68 RNCLEKAVAALDGAKYCLAFASGLAAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVAS 126 + LEK +AAL+G K LA ASG AA + +T L +AGD I+ ++YGGT F+ Sbjct: 60 VDVLEKRLAALEGGKAALATASGHAAQFLALTTLAQAGDNIVSTPNLYGGTFNQFKVTLK 119 Query: 127 EFGLKISFVDCSKIKLLEAAITPE-TKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 G+++ F + A+T E T+ W+E+ NP + D+E A + G + L+ Sbjct: 120 RLGIEVRFTSREERPEEFLALTDEKTRAWWVESIGNPALNIPDLEALAQAAREKG-VALI 178 Query: 186 VDNTF-MSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV------------------- 225 VDNTF M Y RPLA GA + +S TK++ GH V+ G + Sbjct: 179 VDNTFGMGGYLLRPLAWGAALVTHSLTKWVGGHGAVIAGAIVDGGNFPWEGGRYPLLTEP 238 Query: 226 -----SVNCESLHNRLRFLQNSL-------GAVPSPIDCYLCNRGLKTLHVRMEKHFKNG 273 + L F+ + G P + ++ G++TL +R E+H +N Sbjct: 239 QPGYHGLRLTEAFGELAFIVKARVDGLRDQGQALGPFEAWVVLLGMETLSLRAERHVENT 298 Query: 274 MAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMV-TFYIKGTLQHAEIFLKNL 332 + +A +L P V V YPGLP HP H+ ++ G G V TF +KG + A+ F+ L Sbjct: 299 LHLAHWLLEQPQVAWVNYPGLPHHPHHDRAQKYFKGKPGAVLTFGLKGGYEAAKRFISRL 358 Query: 333 KLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQ 392 KL + ++G +LA PA TH+ + ++ G+S ++RLSVGLE EDL +L + Sbjct: 359 KLISHLANVGDTRTLAIHPASTTHSQLSPEEQAQAGVSPEMVRLSVGLEHVEDLKAELKE 418 Query: 393 AL 394 AL Sbjct: 419 AL 420 >2FQ6-A nrPDB Length = 415 Score = 182 bits (461), Expect = 3e-46, Method: Compositional matrix adjust. Identities = 125/402 (31%), Positives = 210/402 (52%), Gaps = 26/402 (6%) Query: 10 GFLPHFQHFA-----TQAIHVGQDPEQWTSRAVVPPISLSTTF-------KQGAPGQHSG 57 G +P H A TQ ++ G+ +++T AV I +++ K+ A + Sbjct: 13 GLVPRGSHMADKKLDTQLVNAGRS-KKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRAN 71 Query: 58 FE--YSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATV-TITHLLKAGDQIICMDDVY 114 E Y R G T L++A+ L+G C+ F G AA +I ++ GD ++ + Y Sbjct: 72 GELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAY 131 Query: 115 GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAH 174 + + ++ S+ G+ S+ D + + P TK+V++E+P + T +V D+ Sbjct: 132 EPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVA 191 Query: 175 IVHKH-GDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLH 233 V D I+++DNT+ + + L G D+S+ +ATKY+ GHSD ++G N Sbjct: 192 AVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCWE 251 Query: 234 NRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPG 293 +LR +G + Y+ +RGL+TL VR+ +H ++ + VA++L +P V +V +P Sbjct: 252 -QLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPA 310 Query: 294 LPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI--FLKNLKLFTLAESLGGFES--LAE 349 LP HE KR TG +G+ +F +K L + E+ +L N LF++A S GG+ES LA Sbjct: 311 LPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILAN 370 Query: 350 LPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLD 391 P H + ++ ++ S TLIRL +GLED +DL+ DLD Sbjct: 371 QP---EHIAAIRPQGEI-DFSGTLIRLHIGLEDVDDLIADLD 408 >4OC9-A nrPDB Length = 424 Score = 178 bits (451), Expect = 4e-45, Method: Compositional matrix adjust. Identities = 124/410 (30%), Positives = 203/410 (49%), Gaps = 50/410 (12%) Query: 33 TSRAVVPPISLSTTFK-----QGAPG---QHSGFEYSRSGNPTRNCLEKAVAALDGAKYC 84 T R++ PI +T + Q A Q G YSR NPT + L + +A ++G + Sbjct: 19 TQRSISVPIYQNTAYNFENLDQAAARFNLQELGNIYSRLSNPTSDVLGQRLANVEGGAFG 78 Query: 85 LAFASGLAATV-TITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLL 143 + ASG+AA + +L +GD + + +YGGT FG++ D + L Sbjct: 79 IPVASGMAACFYALINLASSGDNVAYSNKIYGGTQTLISHTLKNFGIEAREFDIDDLDSL 138 Query: 144 EAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGA 203 E I TK ++ E+ +NP + DIE I KH I+ + DNT +P+ +P G Sbjct: 139 EKVIDQNTKAIFFESLSNPQIAIADIEKINQIAKKH-KIVSICDNTVATPFLLQPFKHGV 197 Query: 204 DISMYSATKYMNGHSDVVMGLVSVNCESLHNRLR-------------------------- 237 D+ ++S +KY++G + G + + + L++ L+ Sbjct: 198 DVIVHSLSKYVSGQGTALGGAL-IERKDLNDLLKNNDRYKAFNTPDPSYHGLNLNTLDLP 256 Query: 238 ---------FLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEK 288 +L++ LGA +P + +L +GL+TL VR+EKH +N VA FL S+P ++ Sbjct: 257 IFSIRVIITWLRD-LGASLAPQNAWLLLQGLETLAVRIEKHSQNAEKVANFLNSHPDIKG 315 Query: 289 VIYPGLPSHPQHELVKR--QCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFES 346 V YP L S+ H L K+ +G+++F K +HA +LF LA +LG +S Sbjct: 316 VNYPTLASNAYHNLFKKYFDKNFASGLLSFEAK-DYEHARRICDKTQLFLLAANLGDSKS 374 Query: 347 LAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKA 396 L PA TH+ + + + GI+ IRLS+GLE+ +DL+ DL QA+++ Sbjct: 375 LIIHPASTTHSQLSEEELQKAGITKATIRLSIGLENSDDLIADLKQAIES 424 >3RI6-A nrPDB Length = 430 Score = 174 bits (442), Expect = 5e-44, Method: Compositional matrix adjust. Identities = 138/414 (33%), Positives = 213/414 (51%), Gaps = 34/414 (8%) Query: 11 FLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFK--------QGAPGQHSGFEYSR 62 F H + F T+A+HV + ++ A+ P+ + F+ Q + G+ G YSR Sbjct: 20 FQGHMRGFTTRALHVPK-AKRDVHGALRTPVYDNAAFEFENSDEIAQVSLGRALGHVYSR 78 Query: 63 SGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYF 121 S NPT LE+ + L GA LA SG+AA T I L +AGD ++ D ++G T F Sbjct: 79 SSNPTVEDLEQRLKNLTGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLF 138 Query: 122 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 ++ FG+++ FVD +E A TKL+++ET +NP +V D+E + +VH G Sbjct: 139 QKTLPSFGIEVRFVDVMDSLAVEHACDETTKLLFLETISNPQLQVADLEALSKVVHAKG- 197 Query: 182 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS----VNCESLHN--- 234 I LVVD T PY LG DI + S+TK+++G V G++ +SL + Sbjct: 198 IPLVVDTTMTPPYLLEAKRLGVDIEVLSSTKFISGGGTSVGGVLIDHGLFEWKSLPSLAP 257 Query: 235 --------------RLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFL 280 R QN LG SP + YL + GL+T+ +R+E+ +N +A +L Sbjct: 258 YYAKAGPMAFLYKARKEVFQN-LGPSLSPHNAYLQSLGLETMALRIERSCQNAQELAHWL 316 Query: 281 ESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAES 340 S P V+ V +P LP P + + KRQ ++TF ++ + + F+ LKL A + Sbjct: 317 LSIPQVKCVNHPSLPDSPFYAIAKRQFRYAGSILTFELESK-EASYRFMDALKLIRRATN 375 Query: 341 LGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394 + +SL P + +A +R L IS ++RLSVG+E+ EDL ED+ QAL Sbjct: 376 IHDNKSLILSPYHVIYALNSHEERLKLEISPAMMRLSVGIEEIEDLKEDILQAL 429 >2CB1-A nrPDB Length = 412 Score = 162 bits (411), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 120/369 (32%), Positives = 190/369 (51%), Gaps = 33/369 (8%) Query: 57 GFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIICMDDVYG 115 G+ Y+R +PT LE+ + AL+GA + ASG A + LL+ GD+++ ++G Sbjct: 47 GYVYARQKDPTAKALEERLKALEGALEAVVLASGQAATFAALLALLRPGDEVVAAKGLFG 106 Query: 116 GTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 175 T F QV S G+ + +VD + EA ++ +T+ V++ET NP V D+E A + Sbjct: 107 QTIGLFGQVLSLMGVTVRYVDPEPEAVREA-LSAKTRAVFVETVANPALLVPDLEALATL 165 Query: 176 VHKHGDIILVVDNTF-MSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV-SVNCESLH 233 + G + LVVDNTF + RPLA GA + + S TK+ +GH V+ G V S E Sbjct: 166 AEEAG-VALVVDNTFGAAGALCRPLAWGAHVVVESLTKWASGHGSVLGGAVLSRETELWR 224 Query: 234 NRLRFLQNSL-GAVP-------------------------SPIDCYLCNRGLKTLHVRME 267 N +FLQ L G +P SP + YL +GL+T+ +R+ Sbjct: 225 NYPQFLQPDLKGQIPWEALRARCFPERVRTLGLSLCGMALSPFNAYLLFQGLETVALRVA 284 Query: 268 KHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI 327 + + +A+ L+ +P V+ + YPGLP P H ++ ++T + G L+ A Sbjct: 285 RMSETARFLAERLQGHPKVKALRYPGLPEDPAHRNARKYLASGGPILTLDL-GDLERASR 343 Query: 328 FLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLL 387 FL ++L A +LG +L P TH+ + + R G++ L+R+SVGLED DLL Sbjct: 344 FLGAIRLLK-AANLGDARTLLVHPWTTTHSRLKEEARLQAGVTPGLVRVSVGLEDPLDLL 402 Query: 388 EDLDQALKA 396 ++AL+A Sbjct: 403 ALFEEALEA 411 >1V2E-A nrPDB Length = 381 Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 34/124 (27%), Positives = 57/124 (45%), Gaps = 21/124 (16%) Query: 92 AATVTITHLLKAGDQIICMD---DVY-------GGTNRYFRQVASEFGLKISFVDCSKIK 141 A V + L+ GD+++ ++ DVY G R R + G ++ + Sbjct: 90 ALYVLLQSLVGPGDEVVVLEPFFDVYLPDAFLAGAKARLVRLDLTPEGFRLD------LS 143 Query: 142 LLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTFMSPYF-QR 197 LE A+TP T+ + + TP NPT V ++E A + H D+ L+ D + Y+ +R Sbjct: 144 ALEKALTPRTRALLLNTPMNPTGLVFGERELEAIARLARAH-DLFLISDEVYDELYYGER 202 Query: 198 PLAL 201 P L Sbjct: 203 PRRL 206 >3NYS-A nrPDB Length = 367 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 37/123 (30%), Positives = 53/123 (43%), Gaps = 15/123 (12%) Query: 66 PTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKA--GDQIICMDDVYGGTNRYFRQ 123 P LE +A GAKYC++ A+G A + L GD++I Y T + Sbjct: 35 PEVTELEDRLADFVGAKYCISCANGTDALQIVQMALGVGPGDEVITPGFTYVAT----AE 90 Query: 124 VASEFGLKISFVDCS------KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 177 + G K +VD +LLEAAITP TK + P + + D + I Sbjct: 91 TVALLGAKPVYVDIDPRTYNLDPQLLEAAITPRTKAII---PVSLYGQCADFDAINAIAS 147 Query: 178 KHG 180 K+G Sbjct: 148 KYG 150 >3B46-A nrPDB Length = 447 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 50/185 (27%), Positives = 77/185 (41%), Gaps = 44/185 (23%) Query: 100 LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLL---------------- 143 LL AGD++I + + ++Y + G K+ +V + K L Sbjct: 138 LLNAGDEVIVFEPFF---DQYIPNIEL-CGGKVVYVPINPPKELDQRNTRGEEWTIDFEQ 193 Query: 144 -EAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIIL---VVDNTFMSPYFQ 196 E AIT +TK V I TP NP KV ++ +I KH +I+ V ++ + + F Sbjct: 194 FEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKHNVVIISDEVYEHLYFTDSFT 253 Query: 197 RPLALGADISMYSATKYMNGHSDVVMG-----LVSVNCESL------HNRLRFLQNSLGA 245 R L +I + T G S G ++S+N E L H R+ F A Sbjct: 254 RIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYAAKAHTRICF------A 307 Query: 246 VPSPI 250 PSP+ Sbjct: 308 SPSPL 312 >4M2J-A nrPDB Length = 406 Score = 38.1 bits (87), Expect = 0.007, Method: Compositional matrix adjust. Identities = 28/114 (24%), Positives = 46/114 (40%), Gaps = 3/114 (2%) Query: 61 SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRY 120 S+ G R + A D + + S A +T+ LL GD+++ + +Y Y Sbjct: 83 SQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHY 142 Query: 121 FRQVASEFG-LKISFVDCSKIK--LLEAAITPETKLVWIETPTNPTQKVIDIEG 171 R + L V +I +L +TP T V + P NPT + +G Sbjct: 143 PRAAGCDVAVLPGRAVRDGEIDPDVLAGLVTPGTAAVIVNFPHNPTGVTLSPQG 196 >2Z61-A nrPDB Length = 370 Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Query: 88 ASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI 147 S L ++ ++ GD+++ + Y + R + G K F D + ++ LE A+ Sbjct: 97 GSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRFL----GAKPVFCDFT-VESLEEAL 151 Query: 148 TPETKLVWIETPTNPTQKVIDIE 170 + +TK + I +P+NP +VID E Sbjct: 152 SDKTKAIIINSPSNPLGEVIDRE 174 >6F35-A nrPDB Length = 410 Score = 35.4 bits (80), Expect = 0.046, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 3/51 (5%) Query: 143 LEAAITPETKLVWIETPTNPT---QKVIDIEGCAHIVHKHGDIILVVDNTF 190 LEAAITP T+ V + +P+NP+ D ++ +H + L+VD+ + Sbjct: 167 LEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLEVLLRHPHVWLLVDDMY 217 >3GPU-A nrPDB Length = 256 Score = 35.0 bits (79), Expect = 0.064, Method: Compositional matrix adjust. Identities = 16/35 (45%), Positives = 19/35 (54%), Gaps = 3/35 (8%) Query: 53 GQHSGFEYSRSGNPTRNC---LEKAVAALDGAKYC 84 GQH + Y R GNP + C +EK V A G YC Sbjct: 217 GQHHLYVYGRQGNPCKRCGTPIEKTVVAGRGTHYC 251 >1YIY-A nrPDB Length = 429 Score = 33.5 bits (75), Expect = 0.15, Method: Compositional matrix adjust. Identities = 33/113 (29%), Positives = 52/113 (46%), Gaps = 15/113 (13%) Query: 92 AATVTITHLLKAGDQIICMD---DVY-------GGTNRYFRQVASEFGLKISFVDCS-KI 140 A TI + GD++I ++ D Y GG R+ ++ G IS D Sbjct: 113 ALYATIQGHVDEGDEVIIIEPFFDCYEPMVKAAGGIPRFIPLKPNKTGGTISSADWVLDN 172 Query: 141 KLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTF 190 LEA +TK++ I TP NP KV+D +E A++ K +++ V D + Sbjct: 173 NELEALFNEKTKMIIINTPHNPLGKVMDRAELEVVANLCKKW-NVLCVSDEVY 224 >3IF2-A nrPDB Length = 444 Score = 33.5 bits (75), Expect = 0.19, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 23/38 (60%), Gaps = 2/38 (5%) Query: 159 PTNPTQKVIDIEGCAHI--VHKHGDIILVVDNTFMSPY 194 PTNPT V+ E AH+ + K DI L++DN + P+ Sbjct: 215 PTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYGMPF 252 >1L1Z-A nrPDB Length = 274 Score = 33.1 bits (74), Expect = 0.21, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 21/41 (51%), Gaps = 5/41 (12%) Query: 49 QGAPG--QHSGFEYSRSGNPTRNC---LEKAVAALDGAKYC 84 QG G QH + Y R GNP + C +EK V A G YC Sbjct: 229 QGEAGTFQHHLYVYGRQGNPCKRCGTPIEKTVVAGRGTHYC 269 >3JTX-A nrPDB Length = 396 Score = 32.7 bits (73), Expect = 0.32, Method: Compositional matrix adjust. Identities = 22/83 (26%), Positives = 38/83 (45%), Gaps = 10/83 (12%) Query: 129 GLKISFVDCS------KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIV---HKH 179 G +I F +C + + + TKLV++ +P NP+ V+D++G + K+ Sbjct: 141 GGEIHFANCPAPSFNPDWRSISEEVWKRTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKY 200 Query: 180 GDIILVVDNTFMSPYFQRPLALG 202 G I+ D + YF LG Sbjct: 201 G-FIIASDECYSEIYFDGNKPLG 222 >6F77-B nrPDB Length = 400 Score = 32.3 bits (72), Expect = 0.42, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 43/88 (48%), Gaps = 10/88 (11%) Query: 139 KIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDN-----TF 190 K + L+ AITP+TK +P+NP+ +++ ++ KH + ++ D+ T+ Sbjct: 153 KAEDLDRAITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTY 212 Query: 191 MSPYFQRPLALGADISMYSATKYMNGHS 218 F P+ + + +Y T MNG S Sbjct: 213 GDFRFATPVEV--EPGLYERTLTMNGVS 238 >3CAI-A nrPDB Length = 406 Score = 31.6 bits (70), Expect = 0.57, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 39/78 (50%), Gaps = 7/78 (8%) Query: 123 QVASEFGLKISF--VDCSKIKL----LEAAITPETKLVWIETPTNPTQKVIDIEGCAHIV 176 + A +G K+ + VD +L E+ I+ T+LV + + + V D+ +V Sbjct: 132 RAAHRYGAKVKWAEVDIETGELPTWQWESLISKSTRLVAVNSASGTLGGVTDLRAMTKLV 191 Query: 177 HKHGDIILVVDNTFMSPY 194 H G ++ VVD++ +PY Sbjct: 192 HDVGALV-VVDHSAAAPY 208 >1U08-A nrPDB Length = 386 Score = 31.6 bits (70), Expect = 0.63, Method: Compositional matrix adjust. Identities = 40/177 (22%), Positives = 70/177 (39%), Gaps = 34/177 (19%) Query: 92 AATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGL--KISF------VDCSKIKLL 143 A IT L++ GD++IC D Y + Y +A G+ +++ VD + L Sbjct: 103 ALYAAITALVRNGDEVICFDPSY---DSYAPAIALSGGIVKRMALQPPHFRVDWQEFAAL 159 Query: 144 EAAITPETKLVWIETPTNPTQKV---IDIEGCAHIVHKHGDIILVVDNTFMSPYF----- 195 ++ T+LV + TP NP+ V D + H +I ++ D + F Sbjct: 160 ---LSERTRLVILNTPHNPSATVWQQADFAALWQAIAGH-EIFVISDEVYEHINFSQQGH 215 Query: 196 ----------QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNS 242 +R +A+ + Y T + G+ V +S +H L F N+ Sbjct: 216 ASVLAHPQLRERAVAVSSFGKTYHMTGWKVGYC-VAPAPISAEIRKVHQYLTFSVNT 271 >4R2N-A nrPDB Length = 367 Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust. Identities = 21/85 (24%), Positives = 42/85 (49%), Gaps = 6/85 (7%) Query: 123 QVASEFGLKISFVDCS-KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHK-HG 180 +VA +++ D + + + A +T T+L+++ P NPT V+ + A V Sbjct: 119 RVAGAIPIQVPLTDHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPA 178 Query: 181 DIILVVDNTFMSPYFQ---RPLALG 202 I++ +D ++ Y + RP +LG Sbjct: 179 HILIAIDEAYVE-YIRDGMRPDSLG 202 >1GC4-A nrPDB Length = 385 Score = 31.6 bits (70), Expect = 0.73, Method: Compositional matrix adjust. Identities = 18/48 (37%), Positives = 25/48 (52%), Gaps = 4/48 (8%) Query: 146 AITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTF 190 AITP TK + + +P NPT V +E A + +H D LV D + Sbjct: 160 AITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEH-DFYLVSDEIY 206 >3FFH-A nrPDB Length = 363 Score = 30.8 bits (68), Expect = 0.97, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 146 AITPETKLVWIETPTNPTQKVIDIEGCAHIVHK-HGDIILVVDNTFMSPYFQRP 198 AI +T +VWI P NPT I++ + + D+++V+D ++ +P Sbjct: 151 AIDEKTTIVWICNPNNPTGNYIELADIQAFLDRVPSDVLVVLDEAYIEYVTPQP 204 >3G7Q-A nrPDB Length = 417 Score = 30.8 bits (68), Expect = 1.0, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 29/51 (56%), Gaps = 4/51 (7%) Query: 147 ITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTFMSPY 194 I ET ++ + PTNPT VI ++ + ++H +I LV+DN + P+ Sbjct: 177 IGEETGMICVSRPTNPTGNVITDEELMKLDRLANQH-NIPLVIDNAYGVPF 226 >1J32-A nrPDB Length = 388 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 16/45 (35%), Positives = 25/45 (55%), Gaps = 3/45 (6%) Query: 143 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIIL 184 + AITP+TKL+ TP+NPT V ++ A + + G +L Sbjct: 156 IRQAITPKTKLLVFNTPSNPTGMVYTPDEVRAIAQVAVEAGLWVL 200 >4NFY-A nrPDB Length = 307 Score = 29.6 bits (65), Expect = 2.3, Method: Compositional matrix adjust. Identities = 14/50 (28%), Positives = 25/50 (50%), Gaps = 9/50 (18%) Query: 164 QKVIDIEGCAHIVHKHGDIILVVD---------NTFMSPYFQRPLALGAD 204 +++ID EG I+ + D+I + D N F +F P+ +GA+ Sbjct: 218 KEIIDEEGLIRIMREREDLIYITDVAPTSKVFNNEFKGRFFATPIKIGAE 267 >1D2F-A nrPDB Length = 390 Score = 29.6 bits (65), Expect = 2.5, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 116 GTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGC 172 G R VA E F D K++ + A PE K++ + +P NPT KV ++E Sbjct: 130 GNQRTVMPVALEKQADGWFCDMGKLEAVLA--KPECKIMLLCSPQNPTGKVWTCDELEIM 187 Query: 173 AHIVHKHG 180 A + +HG Sbjct: 188 ADLCERHG 195 >4I9T-A nrPDB Length = 310 Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust. Identities = 23/100 (23%), Positives = 42/100 (42%), Gaps = 8/100 (8%) Query: 228 NCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLE------ 281 N S+H+ + +L + LG YL +T+ + M+K + + V + E Sbjct: 74 NMISVHHGMVYLHHELGKFLDDAKYYLSAYPNETIVMSMKKDYDSDSKVTKTFEEIFREY 133 Query: 282 --SNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIK 319 +NP + + Y G ++P + K + M YIK Sbjct: 134 YYNNPQYQNLFYTGSNANPTLKETKGKIVLFNRMGGTYIK 173 >4WP0-A nrPDB Length = 472 Score = 28.9 bits (63), Expect = 4.2, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 19/92 (20%) Query: 143 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF--------- 190 L T TK + + TP NP KV ++E A + +H D++ + D + Sbjct: 167 LAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQ 225 Query: 191 ------MSPYFQRPLALGADISMYSATKYMNG 216 + ++R L +G+ +SAT + G Sbjct: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 >4AEE-A nrPDB Length = 696 Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust. Identities = 27/90 (30%), Positives = 43/90 (47%), Gaps = 7/90 (7%) Query: 100 LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPE-----TKLV 154 L K +Q I ++ G Y Q+ ++F + D + K + + PE +KLV Sbjct: 49 LRKIEEQGIVYLKLWPGEYGYGFQIDNDFE-NVLDPDNEEKKCVHTSFFPEYKKCLSKLV 107 Query: 155 WIETPTNPTQKVIDIEGCAHIVHKHGDIIL 184 I+ P NP K+I IE I +G+II+ Sbjct: 108 -IKEPDNPLDKIIHIEESGFIHKFNGEIII 136 >3FVS-A nrPDB Length = 422 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 22/92 (23%), Positives = 39/92 (42%), Gaps = 19/92 (20%) Query: 143 LEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF--------- 190 L T TK + + TP NP KV ++E A + +H D++ + D + Sbjct: 167 LAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQWMVYDGHQ 225 Query: 191 ------MSPYFQRPLALGADISMYSATKYMNG 216 + ++R L +G+ +SAT + G Sbjct: 226 HISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 >5W70-A nrPDB Length = 445 Score = 28.5 bits (62), Expect = 5.4, Method: Compositional matrix adjust. Identities = 45/186 (24%), Positives = 77/186 (41%), Gaps = 18/186 (9%) Query: 73 KAVAALDGAKYCLAFASGLAATVTITHL--LKAGDQIIC--MDDVYGGTNRYFRQVASEF 128 +A AA +G +C+ ASG A+ + + AGD++I + V G+ F Sbjct: 80 RAFAAYNGVPHCVPAASGTASLMLALEACGIGAGDEVIVPGLSWVASGSTILGVNAVPIF 139 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 C + +EAAIT T+ + + + + D++ + I +HG + L+ D Sbjct: 140 CDVDPDTLCLSPEAVEAAITEHTRAIVV---VHLYSALADMDALSAIAERHG-LPLIEDC 195 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVM----GLVSVNCESLHNRLRFLQ---N 241 R + +GA + +A + HS V+ G V E R+ L+ Sbjct: 196 AQAHGATYRGVKVGA---LATAGTFSMQHSKVLTSGEGGAVITRDEDFARRVEHLRADGR 252 Query: 242 SLGAVP 247 L AVP Sbjct: 253 CLSAVP 258 >2X5D-A nrPDB Length = 412 Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust. Identities = 34/182 (18%), Positives = 74/182 (40%), Gaps = 26/182 (14%) Query: 143 LEAAI---TPETKLVWIETPTNPTQKVIDIEGCAHIV--HKHGDIILVVDNTFMSPYF-- 195 LE AI P+ +++ + P+NPT + ++++ +V K D+++V D + + Sbjct: 162 LERAIRESIPKPRMMILGFPSNPTAQCVELDFFERVVALAKQYDVMVVHDLAYADIVYDG 221 Query: 196 -------QRPLALGADISMYSATK----------YMNGHSDVVMGLVSVNCESLHNRLRF 238 Q P A + ++ +K +M G+ ++V L + +S H+ F Sbjct: 222 WKAPSIMQVPGAKDIAVEFFTLSKSYNMAGWRIGFMVGNPELVSALARI--KSYHDYGTF 279 Query: 239 LQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHP 298 + A+ + C R + + + G+ A ++ NP ++ +P Sbjct: 280 TPLQVAAIAALEGDQQCVRDIARQYQQRRDVLVKGLREAGWMVENPKASMYVWAKIPEPY 339 Query: 299 QH 300 H Sbjct: 340 AH 341 >1T3I-A nrPDB Length = 420 Score = 28.1 bits (61), Expect = 7.6, Method: Compositional matrix adjust. Identities = 24/90 (26%), Positives = 43/90 (47%), Gaps = 5/90 (5%) Query: 101 LKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSK-----IKLLEAAITPETKLVW 155 LKAGD+II + ++ VA++ G + FV + ++ + ++ +TKLV Sbjct: 115 LKAGDEIITTVMEHHSNLVPWQMVAAKTGAVLKFVQLDEQESFDLEHFKTLLSEKTKLVT 174 Query: 156 IETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 + +N V E A + H+ G +LV Sbjct: 175 VVHISNTLGCVNPAEEIAQLAHQAGAKVLV 204 >4MY5-A nrPDB Length = 393 Score = 28.1 bits (61), Expect = 7.9, Method: Compositional matrix adjust. Identities = 33/143 (23%), Positives = 60/143 (41%), Gaps = 27/143 (18%) Query: 70 CLEKAVAALDGAKYCLAF----------ASGLAATVTITHLLKAGDQIICMDDVYGGTNR 119 L +A +A KY L + + A + ++T +L+ GD+++ Y G Sbjct: 73 ALRQAASAFVKEKYHLTYNPDNEILVTIGATEALSASLTAILEPGDKVLLPAPAYPG--- 129 Query: 120 YFRQVASEFGLKISFVDCSK------IKLLEAAITPE---TKLVWIETPTNPTQKVI--- 167 + V + G ++ +D ++LE AI E K V + PTNPT Sbjct: 130 -YEPVVNLVGAEVVEIDTRSNDFVLTPEMLEEAILKEGEALKAVILNYPTNPTGVTYSRQ 188 Query: 168 DIEGCAHIVHKHGDIILVVDNTF 190 I+ A ++ K+ I ++ D + Sbjct: 189 QIKNLAEVLKKY-PIFVISDEVY 210 >1O4S-A nrPDB Length = 389 Score = 27.7 bits (60), Expect = 8.2, Method: Compositional matrix adjust. Identities = 38/155 (24%), Positives = 64/155 (41%), Gaps = 24/155 (15%) Query: 75 VAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISF 134 V +GAK L F + +A LL GD++I V+ Y Q+ G ++ Sbjct: 104 VVVTNGAKQAL-FNAFMA-------LLDPGDEVIVFSPVWVS---YIPQIILAGG-TVNV 151 Query: 135 VDC-------SKIKLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIIL 184 V+ ++ +E + +TK V I +P NPT V +EG + K + + Sbjct: 152 VETFMSKNFQPSLEEVEGLLVGKTKAVLINSPNNPTGVVYRREFLEGLVRLAKKR-NFYI 210 Query: 185 VVDNTFMSPYFQRPLALGADISM-YSATKYMNGHS 218 + D + S + D+S + Y+NG S Sbjct: 211 ISDEVYDSLVYTDEFTSILDVSEGFDRIVYINGFS 245 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5TSU-A nrPDB 642 0.0 4IYO-A nrPDB 544 e-155 3MKJ-A nrPDB 543 e-155 6CJB-A nrPDB 540 e-154 4L0O-H nrPDB 540 e-154 1E5F-A nrPDB 538 e-153 5DX5-A nrPDB 530 e-151 5X5H-A nrPDB 529 e-151 3VK2-A nrPDB 510 e-145 1N8P-A nrPDB 495 e-140 1IBJ-A nrPDB 489 e-139 3AEO-A nrPDB 487 e-138 3QI6-A nrPDB 486 e-138 1CS1-A nrPDB 485 e-137 1PFF-A nrPDB 473 e-134 1I43-A nrPDB 451 e-127 4KAM-A nrPDB 446 e-126 4U1T-A nrPDB 445 e-125 3NDN-A nrPDB 437 e-123 4OC9-A nrPDB 435 e-122 2CTZ-A nrPDB 432 e-121 5IJG-A nrPDB 414 e-116 3RI6-A nrPDB 412 e-115 2FQ6-A nrPDB 397 e-111 2CB1-A nrPDB 369 e-102 1V2E-A nrPDB 87 2e-17 Sequences not found previously or not previously below threshold: 3NYS-A nrPDB 62 6e-10 1M6S-A nrPDB 61 6e-10 3UWC-A nrPDB 60 2e-09 3OP7-A nrPDB 59 3e-09 2Z61-A nrPDB 56 3e-08 1YIY-A nrPDB 55 8e-08 2OGE-A nrPDB 55 8e-08 2GB3-A nrPDB 54 1e-07 1O4S-A nrPDB 52 4e-07 1J32-A nrPDB 52 5e-07 2ZJG-A nrPDB 51 8e-07 3CAI-A nrPDB 51 1e-06 1U08-A nrPDB 51 1e-06 5TXT-B nrPDB 50 2e-06 1MDZ-A nrPDB 50 2e-06 4BMK-A nrPDB 49 3e-06 5W70-A nrPDB 49 3e-06 3B46-A nrPDB 49 4e-06 3LVM-A nrPDB 49 4e-06 3W1J-A nrPDB 48 6e-06 3W1H-A nrPDB 48 6e-06 1GC4-A nrPDB 48 6e-06 5K8B-A nrPDB 48 9e-06 3DR4-A nrPDB 47 1e-05 5YHV-A nrPDB 47 2e-05 4WP0-A nrPDB 46 2e-05 3FVS-A nrPDB 46 2e-05 2O0R-A nrPDB 46 2e-05 5XT5-A nrPDB 46 3e-05 4PIW-A nrPDB 46 3e-05 1XI9-A nrPDB 46 4e-05 1GDE-A nrPDB 46 4e-05 4MY5-A nrPDB 46 4e-05 5HH9-A nrPDB 45 4e-05 5WMH-A nrPDB 45 6e-05 3L8A-A nrPDB 45 8e-05 2DOU-A nrPDB 44 1e-04 6F35-A nrPDB 44 2e-04 3WGB-A nrPDB 43 3e-04 4ZWV-A nrPDB 42 4e-04 4Q75-A nrPDB 42 4e-04 6BLG-A nrPDB 42 4e-04 2AEV-A nrPDB 42 5e-04 4W91-A nrPDB 42 5e-04 1T3I-A nrPDB 42 5e-04 6HRH-B nrPDB 41 7e-04 3EUC-A nrPDB 41 0.001 3WY7-A nrPDB 41 0.001 1BW0-A nrPDB 41 0.001 4OTL-A nrPDB 41 0.001 2O1B-A nrPDB 41 0.001 2X8U-A nrPDB 41 0.001 3DZZ-A nrPDB 40 0.002 3FFH-A nrPDB 40 0.002 4J8L-A nrPDB 40 0.002 4M2J-A nrPDB 40 0.002 4P3M-A nrPDB 40 0.002 2FNU-A nrPDB 40 0.003 1B9H-A nrPDB 39 0.005 4R2N-A nrPDB 38 0.005 1IJI-A nrPDB 37 0.013 4LNJ-A nrPDB 37 0.015 6F77-B nrPDB 37 0.018 4FL0-A nrPDB 36 0.022 3IF2-A nrPDB 36 0.025 3G7Q-A nrPDB 36 0.026 4CVQ-A nrPDB 36 0.026 5WGB-A nrPDB 36 0.027 3MAF-B nrPDB 36 0.031 5DJ3-A nrPDB 36 0.035 3HDO-A nrPDB 35 0.064 1D2F-A nrPDB 35 0.076 1LC8-A nrPDB 35 0.088 3G8M-A nrPDB 35 0.095 2YRI-A nrPDB 34 0.11 6C9E-A nrPDB 34 0.14 3CQ5-A nrPDB 33 0.17 3A2B-A nrPDB 33 0.26 4WBT-A nrPDB 33 0.26 1DJ9-A nrPDB 33 0.30 3QGU-A nrPDB 32 0.38 3GBX-A nrPDB 32 0.39 6ONN-A nrPDB 32 0.56 3ELE-A nrPDB 32 0.56 3EZS-A nrPDB 32 0.57 5VNX-A nrPDB 31 0.65 3LWS-A nrPDB 31 0.65 4LW2-A nrPDB 31 0.67 6MRE-A nrPDB 31 0.68 3JTX-A nrPDB 31 0.86 2Z9W-A nrPDB 31 1.2 4DUT-A nrPDB 31 1.4 1C7O-A nrPDB 30 1.7 1T6J-A nrPDB 30 1.9 5VMB-A nrPDB 30 2.0 3H14-A nrPDB 29 2.5 5XF9-A nrPDB 29 2.5 4GDY-A nrPDB 29 2.9 3V7N-A nrPDB 29 3.7 2YKV-A nrPDB 29 3.9 4LIS-A nrPDB 29 4.7 3QYQ-A nrPDB 29 5.0 4LHD-A nrPDB 28 5.3 4QAI-A nrPDB 28 6.2 4J5U-A nrPDB 28 6.3 2ZAK-A nrPDB 28 6.3 1WYT-A nrPDB 28 6.6 >5TSU-A nrPDB Length = 422 Score = 642 bits (1656), Expect = 0.0, Method: Composition-based stats. Identities = 401/404 (99%), Positives = 401/404 (99%) Query: 2 QEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYS 61 QEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGF YS Sbjct: 19 QEKDASSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFNYS 78 Query: 62 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYF 121 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTN YF Sbjct: 79 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNLYF 138 Query: 122 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD Sbjct: 139 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 198 Query: 182 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQN 241 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQN Sbjct: 199 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQN 258 Query: 242 SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHE 301 SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHE Sbjct: 259 SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHE 318 Query: 302 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLK 361 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLA SLGGFESLAELPAIMTHASVLK Sbjct: 319 LVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAVSLGGFESLAELPAIMTHASVLK 378 Query: 362 NDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS 405 NDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS Sbjct: 379 NDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAAHPPSGSHS 422 >4IYO-A nrPDB Length = 397 Score = 544 bits (1401), Expect = e-155, Method: Composition-based stats. Identities = 206/383 (53%), Positives = 263/383 (68%), Gaps = 4/383 (1%) Query: 14 HFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEK 73 AT AIH GQ P+ T AV+PPI ++T+ Q +PG+H GFEYSR+ NPTR E+ Sbjct: 13 RALSLATLAIHGGQSPDPSTG-AVMPPIYATSTYAQSSPGEHQGFEYSRTHNPTRFAYER 71 Query: 74 AVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF-GLKI 132 VAAL+G AFASG+AAT T+ LL AG ++ MDD+YGGT R F +V GL Sbjct: 72 CVAALEGGTRAFAFASGMAATSTVMELLDAGSHVVAMDDLYGGTFRLFERVRRRTAGLDF 131 Query: 133 SFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMS 192 SFVD + +AAI +TK+VWIETPTNP K++DI A I KHG ++ VVDNTF S Sbjct: 132 SFVDLTDPAAFKAAIRADTKMVWIETPTNPMLKLVDIAAIAVIARKHG-LLTVVDNTFAS 190 Query: 193 PYFQRPLALGADISMYSATKYMNGHSDVVMG-LVSVNCESLHNRLRFLQNSLGAVPSPID 251 P QRPL+LGAD+ ++SATKY+NGHSD+V G V + L ++ FLQNS+G V P D Sbjct: 191 PMLQRPLSLGADLVVHSATKYLNGHSDMVGGIAVVGDNAELAEQMAFLQNSIGGVQGPFD 250 Query: 252 CYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCT 311 +L RGLKTL +RM H +N +A+AQ+LE++P +EKVIYPGL SHPQH L KRQ +G Sbjct: 251 SFLALRGLKTLPLRMRAHCENALALAQWLETHPAIEKVIYPGLASHPQHVLAKRQMSGFG 310 Query: 312 GMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISD 371 G+V+ +KG A+ F + +LFTLAESLGG ESL PA+MTHAS+ R+ LGISD Sbjct: 311 GIVSIVLKGGFDAAKRFCEKTELFTLAESLGGVESLVNHPAVMTHASIPVARREQLGISD 370 Query: 372 TLIRLSVGLEDEEDLLEDLDQAL 394 L+RLSVG+ED DL DL++AL Sbjct: 371 ALVRLSVGIEDLGDLRGDLERAL 393 >3MKJ-A nrPDB Length = 398 Score = 543 bits (1400), Expect = e-155, Method: Composition-based stats. Identities = 175/394 (44%), Positives = 252/394 (63%), Gaps = 12/394 (3%) Query: 14 HFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGAPG---QHSGFEYSRSGN 65 F TQ +H GQ P+ T A+ PI ++TF +QGA + SG+ Y+R GN Sbjct: 5 RTYGFNTQIVHAGQQPDPSTG-ALSTPIFQTSTFVFDSAEQGAARFALEESGYIYTRLGN 63 Query: 66 PTRNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQV 124 PT + LEK +A L+ + LA ASG++A T T+ L + GD I+ +YG T+ + Sbjct: 64 PTTDALEKKLAVLERGEAGLATASGISAITTTLLTLCQQGDHIVSASAIYGCTHAFLSHS 123 Query: 125 ASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIIL 184 +FG+ +SFVD +K + + AA+ PETK+V+IETP NPT ++DIE A I H+ G + L Sbjct: 124 MPKFGINVSFVDAAKPEEIRAAMRPETKVVYIETPANPTLSLVDIETVAGIAHQQGAL-L 182 Query: 185 VVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSL 243 VVDNTFMSPY Q+PL LGADI ++S TKY+NGH DV+ G++ E + R L++ Sbjct: 183 VVDNTFMSPYCQQPLQLGADIVVHSVTKYINGHGDVIGGIIVGKQEFIDQARFVGLKDIT 242 Query: 244 GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELV 303 G SP + +L RG+KTL +RME+H +N + +A+FLE +P + +V YPGL SHPQ+EL Sbjct: 243 GGCMSPFNAWLTLRGVKTLGIRMERHCENALKIARFLEGHPSITRVYYPGLSSHPQYELG 302 Query: 304 KRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKND 363 +RQ + G+++F I G L+ + +++L LA SLG E+L + PA MTH+ V + Sbjct: 303 QRQMSLPGGIISFEIAGGLEAGRRMINSVELCLLAVSLGDTETLIQHPASMTHSPVAPEE 362 Query: 364 RDVLGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397 R GI+D LIRLSVGLED ED++ DL+ A++ A Sbjct: 363 RLKAGITDGLIRLSVGLEDPEDIINDLEHAIRKA 396 >6CJB-A nrPDB Length = 391 Score = 540 bits (1392), Expect = e-154, Method: Composition-based stats. Identities = 199/380 (52%), Positives = 263/380 (69%), Gaps = 4/380 (1%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVA 76 HF T+AIH GQ+P + T AV+ PI ++T+KQ APG+H G+EYSR+ NPTR E +A Sbjct: 13 HFDTRAIHAGQEPCKSTG-AVMTPIYATSTYKQIAPGEHLGYEYSRTQNPTRKAYEDCIA 71 Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF-GLKISFV 135 +L+ + AFASG+AA T+ LL +GD ++ MDD+YGGT R F +V + L SF+ Sbjct: 72 SLESGQKGFAFASGMAAINTVIDLLGSGDHVVAMDDLYGGTFRLFDKVKTRTSNLSFSFI 131 Query: 136 DCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYF 195 D S + +EAAITP+TKL+W+ETP+NP K+ ++ A I K+ ++I V DNTF +P+ Sbjct: 132 DMSVPENIEAAITPKTKLLWLETPSNPMLKLANLRKIAAIAKKY-NLITVADNTFATPWI 190 Query: 196 QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCES-LHNRLRFLQNSLGAVPSPIDCYL 254 QRPL LG DI ++SATKY+NGHSDVV G+V V S L +++ FLQNS GAV P D +L Sbjct: 191 QRPLELGFDIVLHSATKYLNGHSDVVSGVVVVGDNSVLSDKIAFLQNSCGAVAGPFDSFL 250 Query: 255 CNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMV 314 R LKTL VRM++H +N +A +L S+P +EKVIYPGL SHPQ+ L K Q GM+ Sbjct: 251 VLRSLKTLSVRMQRHCENANHLANWLSSHPKIEKVIYPGLKSHPQYSLAKEQMNNFGGMI 310 Query: 315 TFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLI 374 + +KG+L+ A+ FL +LFTLAESLGG ESL E PAIMTHAS+ R LGI D I Sbjct: 311 SLVLKGSLEDAKRFLARCELFTLAESLGGVESLIEHPAIMTHASIPVEQRKALGIEDGFI 370 Query: 375 RLSVGLEDEEDLLEDLDQAL 394 RLSVG+E +DL DL+ AL Sbjct: 371 RLSVGIEHIDDLRADLEHAL 390 >4L0O-H nrPDB Length = 388 Score = 540 bits (1392), Expect = e-154, Method: Composition-based stats. Identities = 191/380 (50%), Positives = 256/380 (67%), Gaps = 3/380 (0%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVA 76 T+ IH G E T+ AV PI ++T++Q A G+H G+EYSRSGNPTR LE+ +A Sbjct: 2 RMQTKLIHGG-ISEDATTGAVSVPIYQTSTYRQDAIGRHKGYEYSRSGNPTRFALEELIA 60 Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD 136 L+G AFASGLA + LL++GD ++ DDVYGGT R F QV + GL + +D Sbjct: 61 DLEGGVKGFAFASGLAGIHAVFSLLQSGDHVLLGDDVYGGTFRLFNQVLVKNGLSCTIID 120 Query: 137 CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQ 196 S I ++ AI P TK +++ETP+NP K+ D+ CA + HG ++ +VDNTF +PY+Q Sbjct: 121 TSDISQIKKAIKPNTKALYLETPSNPLLKITDLAQCASVAKDHG-LLTIVDNTFATPYYQ 179 Query: 197 RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCN 256 PL LGADI +S TKY+ GHSDVV GLV+ N E+L + F QN++G V P D +L Sbjct: 180 NPLLLGADIVAHSGTKYLGGHSDVVAGLVTTNNEALAQEIAFFQNAIGGVLGPQDSWLLQ 239 Query: 257 RGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTF 316 RG+KTL +RME H KN + VA+FLE +P VE+V YPGLP+HP +EL K+Q G +GM++F Sbjct: 240 RGIKTLGLRMEAHQKNALCVAEFLEKHPKVERVYYPGLPTHPNYELAKKQMRGFSGMLSF 299 Query: 317 YIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRL 376 +K + A F+++LKLF L ESLGG ESL +PA MTHA + K R+ GI D L+RL Sbjct: 300 TLKNDSE-AVAFVESLKLFILGESLGGVESLVGIPAFMTHACIPKTQREAAGIRDGLVRL 358 Query: 377 SVGLEDEEDLLEDLDQALKA 396 SVG+E E+DLLEDL+QA Sbjct: 359 SVGIEHEQDLLEDLEQAFAK 378 >1E5F-A nrPDB Length = 404 Score = 538 bits (1386), Expect = e-153, Method: Composition-based stats. Identities = 161/389 (41%), Positives = 239/389 (61%), Gaps = 12/389 (3%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTRN 69 AT IH +Q+ A +PPI ++TF +QG GQ SG+ Y+R GNPT + Sbjct: 8 PATACIHANPQKDQF--GAAIPPIYQTSTFVFDNCQQGGNRFAGQESGYIYTRLGNPTVS 65 Query: 70 CLEKAVAALDGAKYCLAFASGLAATV-TITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 LE +A L+ + C+A +SG+ A T+ +LKAGD +I + +YG T+ F ++F Sbjct: 66 NLEGKIAFLEKTEACVATSSGMGAIAATVLTILKAGDHLISDECLYGCTHALFEHALTKF 125 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 G+++ F++ + ++ + P TK+V+ ETP NPT K+ID+E H ++++ DN Sbjct: 126 GIQVDFINTAIPGEVKKHMKPNTKIVYFETPANPTLKIIDMERVCKDAHSQEGVLVIADN 185 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGAVP 247 TF SP P+ G D+ ++SATKY+NGH+DVV GL+ + L R+ +++ G+V Sbjct: 186 TFCSPMITNPVDFGVDVVVHSATKYINGHTDVVAGLICGKADLLQQIRMVGIKDITGSVI 245 Query: 248 SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQC 307 SP D +L RGL TL++RM+ +N M VA++L+S+P VEKV YPG H H++ K+Q Sbjct: 246 SPHDAWLITRGLSTLNIRMKAESENAMKVAEYLKSHPAVEKVYYPGFEDHEGHDIAKKQM 305 Query: 308 TGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVL 367 M+TF +K + A+ L NLKL TLA SLGG ESL + PA MTHA V K +R+ Sbjct: 306 RMYGSMITFILKSGFEGAKKLLDNLKLITLAVSLGGCESLIQHPASMTHAVVPKEEREAA 365 Query: 368 GISDTLIRLSVGLEDEEDLLEDLDQALKA 396 GI+D +IRLSVG+ED ++L+ D Q L A Sbjct: 366 GITDGMIRLSVGIEDADELIADFKQGLDA 394 >5DX5-A nrPDB Length = 400 Score = 530 bits (1365), Expect = e-151, Method: Composition-based stats. Identities = 166/390 (42%), Positives = 245/390 (62%), Gaps = 12/390 (3%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTF-----KQGA---PGQHSGFEYSRSGNPTR 68 FAT+AIH G ++ ++ PI ++TF +QG G+ SG+ YSR GNPT Sbjct: 8 GFATKAIHGGHIGDKQFG-SLATPIYQTSTFIFDSAEQGGRRFAGEESGYIYSRLGNPTS 66 Query: 69 NCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 +E +A L+G + + ASG+ A + LK+GD ++ D +YG T + Sbjct: 67 TEVENKLALLEGGEAAVVAASGMGAIAASLWSALKSGDHVVASDTLYGCTFALLNHGLTR 126 Query: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHK-HGDIILVV 186 +G++++FVD S + ++ A+ P TK+V++ETP NPT KV DI +++VH+ + + + V Sbjct: 127 YGVEVTFVDVSNLDEVKNALKPNTKVVYLETPANPTLKVTDIRKISNMVHESNKECFVFV 186 Query: 187 DNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGA 245 DNTF +PY QRPL LGAD+ ++SATKY+NGH DV+ G E ++ +L +++ G+ Sbjct: 187 DNTFCTPYIQRPLELGADVVVHSATKYLNGHGDVIAGFAVGKEEFINQVKLFGIKDMTGS 246 Query: 246 VPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKR 305 V P + +L RG+KTL +RMEKH KN M VA+FLES+P VEKV YPGL S ++L + Sbjct: 247 VTGPFESFLIIRGMKTLQLRMEKHCKNAMEVAKFLESHPAVEKVYYPGLESFKYYQLARE 306 Query: 306 QCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRD 365 Q M++F +KG ++ +I + N+KL TLA SLG E+L + PA MTH+ +R Sbjct: 307 QMKLPGAMISFELKGGVEEGKIVMNNVKLATLAVSLGDSETLIQHPASMTHSPYTAEERK 366 Query: 366 VLGISDTLIRLSVGLEDEEDLLEDLDQALK 395 GISD L+RLSVGLED ED+++DL QAL Sbjct: 367 AAGISDGLVRLSVGLEDAEDIIDDLKQALD 396 >5X5H-A nrPDB Length = 392 Score = 529 bits (1364), Expect = e-151, Method: Composition-based stats. Identities = 181/387 (46%), Positives = 246/387 (63%), Gaps = 7/387 (1%) Query: 11 FLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQ-HSGFEYSRSGNPTRN 69 F P+ Q F+T +IH G +P+ + ++ PI STTF Q AP + G+EY+R GNPT Sbjct: 3 FDPNTQGFSTASIHAGYEPDDYYG-SINTPIYASTTFAQNAPNELRKGYEYTRVGNPTIV 61 Query: 70 CLEKAVAALDGAKYCLAFASGLAATVTIT-HLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 LE+ VAAL+GAKY AF+SG+AAT + +LK GD I+ +D YGGT R V + + Sbjct: 62 ALEQTVAALEGAKYGRAFSSGMAATDILFRIILKPGDHIVLGNDAYGGTYRLIDTVFTAW 121 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDN 188 G++ + VD S ++ ++AAI TKL+W+ETPTNP + DIE A + + + LVVDN Sbjct: 122 GVEYTVVDTSVVEEVKAAIKDNTKLIWVETPTNPALGITDIEAVAKLT-EGTNAKLVVDN 180 Query: 189 TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPS 248 TF SPY Q+PL LGA ++S TKY+ GHSDVV GLV N + + L F+Q +G +PS Sbjct: 181 TFASPYLQQPLKLGAHAVLHSTTKYIGGHSDVVGGLVVTNDQEMDEELLFMQGGIGPIPS 240 Query: 249 PIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCT 308 D YL RGLKTL VRM++H N +A+FL+S P V V+YPGL +HP HE+ +Q Sbjct: 241 VFDAYLTARGLKTLAVRMDRHCDNAEKIAEFLDSRPEVSTVLYPGLKNHPGHEVAAKQMK 300 Query: 309 GCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLG 368 GM++ G + A+ F + KL LAESLGG ESL E PA MTH S + L Sbjct: 301 RFGGMISVRFAGGEEAAKKFCTSTKLICLAESLGGVESLLEHPATMTHQSAAGSQ---LE 357 Query: 369 ISDTLIRLSVGLEDEEDLLEDLDQALK 395 + L+R+S+G+ED EDLL D++QAL Sbjct: 358 VPRDLVRISIGIEDIEDLLADVEQALN 384 >3VK2-A nrPDB Length = 398 Score = 510 bits (1315), Expect = e-145, Method: Composition-based stats. Identities = 173/391 (44%), Positives = 246/391 (62%), Gaps = 12/391 (3%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGA--------PGQHSGFEYSRSGNPTR 68 FAT+AIH G DP+ A+VPP+ + TF G+ +G YSR NPT Sbjct: 9 GFATRAIHHGYDPQDH-GGALVPPVYQTATFTFPTVEYGAACFAGEQAGHFYSRISNPTL 67 Query: 69 NCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 N LE +A+L+G + LA ASG+ A T T+ LL+ GD+++ + +YG T + E Sbjct: 68 NLLEARMASLEGGEAGLALASGMGAITSTLWTLLRPGDEVLLGNTLYGHTFAFLHHGIGE 127 Query: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187 FG+K+ VD + ++ LEAA+TP T++++ E+P NP + DI G A I KHG + VVD Sbjct: 128 FGVKLRHVDMADLQALEAAMTPATRVIYFESPANPNMHMADIAGVAKIARKHGATV-VVD 186 Query: 188 NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGAV 246 NT+ +PY QRPL LGAD+ ++SATKY++GH D+ G+V + + RL+ L++ GAV Sbjct: 187 NTYCTPYLQRPLELGADLVVHSATKYLSGHGDITAGIVVGSQALVDRIRLQGLKDMTGAV 246 Query: 247 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQ 306 SP D L RG+KTL++RM++H N +A+FL P VE + YPGL S PQ+ L ++Q Sbjct: 247 LSPHDAALLMRGIKTLNLRMDRHCANAQVLAEFLARQPQVELIHYPGLASFPQYTLARQQ 306 Query: 307 CTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDV 366 + GM+ F +KG + F+ L+LF+ A SLG ESLA+ PA MTH+S +R Sbjct: 307 MSQPGGMIAFELKGGIGAGRRFMNALQLFSRAVSLGDAESLAQHPASMTHSSYTPEERAH 366 Query: 367 LGISDTLIRLSVGLEDEEDLLEDLDQALKAA 397 GIS+ L+RLSVGLED +DLL D+ QALKA+ Sbjct: 367 YGISEGLVRLSVGLEDIDDLLADVQQALKAS 397 >1N8P-A nrPDB Length = 393 Score = 495 bits (1274), Expect = e-140, Method: Composition-based stats. Identities = 199/387 (51%), Positives = 267/387 (68%), Gaps = 10/387 (2%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSG-FEYSRSGNPTRNCLEKAVA 76 FAT+AIH G+ + +V+ PISLSTTFKQ +P G +EYSRS NP R LE+AVA Sbjct: 8 FATKAIHAGEHVD--VHGSVIEPISLSTTFKQSSPANPIGTYEYSRSQNPNRENLERAVA 65 Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD 136 AL+ A+Y LAF+SG A T TI L G + + DVYGGT+RYF +VA+ G++ SF + Sbjct: 66 ALENAQYGLAFSSGSATTATILQSLPQGSHAVSIGDVYGGTHRYFTKVANAHGVETSFTN 125 Query: 137 CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHG---DIILVVDNTFMSP 193 + L I TKLVWIETPTNPT KV DI+ A ++ KH D+ILVVDNTF+SP Sbjct: 126 -DLLNDLPQLIKENTKLVWIETPTNPTLKVTDIQKVADLIKKHAAGQDVILVVDNTFLSP 184 Query: 194 YFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCY 253 Y PL GADI ++SATKY+NGHSDVV+G+++ N + L+ RL+FLQN++GA+PSP D + Sbjct: 185 YISNPLNFGADIVVHSATKYINGHSDVVLGVLATNNKPLYERLQFLQNAIGAIPSPFDAW 244 Query: 254 LCNRGLKTLHVRMEKHFKNGMAVAQFLESNPW-VEKVIYPGLPSHPQHELVKRQCTGC-- 310 L +RGLKTLH+R+ + + +A+FL ++ V V YPGL +HP +++V +Q Sbjct: 245 LTHRGLKTLHLRVRQAALSANKIAEFLAADKENVVAVNYPGLKTHPNYDVVLKQHRDALG 304 Query: 311 TGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGIS 370 GM++F IKG + A F + +LFTLAESLGG ESL E+PA+MTH + K R+ G+ Sbjct: 305 GGMISFRIKGGAEAASKFASSTRLFTLAESLGGIESLLEVPAVMTHGGIPKEAREASGVF 364 Query: 371 DTLIRLSVGLEDEEDLLEDLDQALKAA 397 D L+R+SVG+ED +DLLED+ QALK A Sbjct: 365 DDLVRISVGIEDTDDLLEDIKQALKQA 391 >1IBJ-A nrPDB Length = 464 Score = 489 bits (1260), Expect = e-139, Method: Composition-based stats. Identities = 158/377 (41%), Positives = 242/377 (64%), Gaps = 4/377 (1%) Query: 19 ATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAAL 78 +T +++ + + A+ P+ + TFKQ + ++ ++Y+RSGNPTR+ LE +A L Sbjct: 88 STLLVNLDNKFDPF--DAMSTPLYQTATFKQPSAIENGPYDYTRSGNPTRDALESLLAKL 145 Query: 79 DGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS 138 D A F SG+AA +THL+K G++I+ DDVYGG++R QV G+ + V+ + Sbjct: 146 DKADRAFCFTSGMAALSAVTHLIKNGEEIVAGDDVYGGSDRLLSQVVPRSGVVVKRVNTT 205 Query: 139 KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRP 198 K+ + AAI P+TKLVW+E+PTNP Q++ DI + + H G ++L VDN+ MSP RP Sbjct: 206 KLDEVAAAIGPQTKLVWLESPTNPRQQISDIRKISEMAHAQGALVL-VDNSIMSPVLSRP 264 Query: 199 LALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG 258 L LGADI M+SATK++ GHSDV+ G+++V E L + FLQNS G+ +P DC+LC RG Sbjct: 265 LELGADIVMHSATKFIAGHSDVMAGVLAVKGEKLAKEVYFLQNSEGSGLAPFDCWLCLRG 324 Query: 259 LKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYI 318 +KT+ +R+EK +N +A +L S+P V+KV Y GLP HP H L Q G + +F I Sbjct: 325 IKTMALRIEKQQENARKIAMYLSSHPRVKKVYYAGLPDHPGHHLHFSQAKGAGSVFSF-I 383 Query: 319 KGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSV 378 G++ ++ ++ K F++A S G +SL +P M+HAS+ R+ G+++ L+R+S Sbjct: 384 TGSVALSKHLVETTKYFSIAVSFGSVKSLISMPCFMSHASIPAEVREARGLTEDLVRISA 443 Query: 379 GLEDEEDLLEDLDQALK 395 G+ED +DL+ DLD A K Sbjct: 444 GIEDVDDLISDLDIAFK 460 >3AEO-A nrPDB Length = 389 Score = 487 bits (1255), Expect = e-138, Method: Composition-based stats. Identities = 151/365 (41%), Positives = 228/365 (62%), Gaps = 11/365 (3%) Query: 40 PISLSTTF-----KQGAP---GQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGL 91 PI ++TF +QGA G+ G YSR GNPT E+ V +++GA AF SG+ Sbjct: 25 PIFQTSTFCFDSTQQGADLFMGKGEGHIYSRLGNPTVEQFEEMVCSIEGAAGSAAFGSGM 84 Query: 92 AATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPE 150 A + L+ GD +I D +YG T F FG+++ +D S ++ ++AA P Sbjct: 85 GAISSSTLAFLQKGDHLIAGDTLYGCTVSLFTHWLPRFGIEVDLIDTSDVEKVKAAWKPN 144 Query: 151 TKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSA 210 TK+V++E+P NPT KV DI+G A + H+ G LVVD TF SP F +PL LGADI+++S Sbjct: 145 TKMVYLESPANPTCKVSDIKGIAVVCHERGAR-LVVDATFTSPCFLKPLELGADIALHSV 203 Query: 211 TKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHF 270 +KY+NGH DV+ G+ S ++F + G++ +P+D +LC RG+KTL +RM+ H Sbjct: 204 SKYINGHGDVIGGVSSAKTAEDIATIKFYRKDAGSLMAPMDAFLCARGMKTLPIRMQIHM 263 Query: 271 KNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLK 330 +NG+ VA+FLE + + KV +PGL S P H++ K+Q TG F +K + + A+ ++ Sbjct: 264 ENGLKVAKFLEQHEKIVKVNHPGLESFPGHDIAKKQMTGYGSTFLFEMK-SFEAAKKLME 322 Query: 331 NLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDL 390 +LK+ TLA SLG ++L E PA MTHA+V +N GI+ L+R+SVG+E+ +D++ DL Sbjct: 323 HLKVCTLAVSLGCVDTLIEHPASMTHAAVPENIMRKQGITPELVRISVGIENVDDIIADL 382 Query: 391 DQALK 395 QAL+ Sbjct: 383 KQALE 387 >3QI6-A nrPDB Length = 392 Score = 486 bits (1252), Expect = e-138, Method: Composition-based stats. Identities = 179/383 (46%), Positives = 237/383 (61%), Gaps = 7/383 (1%) Query: 14 HFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQ-GAPGQHSGFEYSRSGNPTRNCLE 72 F AT+AIH G P+ T AV PI S+TF Q G G G+EY+R+GNPTR LE Sbjct: 14 RFAGLATRAIHSGYRPDPATG-AVNAPIYASSTFAQDGVGGLRGGYEYARTGNPTRTALE 72 Query: 73 KAVAALDGAKYCLAFASGLAAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLK 131 A+AA++ A + AF+SG+AA + +L+ GD ++ DD YGGT R +V + + ++ Sbjct: 73 AALAAVEDAAFGRAFSSGMAAADCALRAMLRPGDHVVIPDDAYGGTFRLIDKVFTGWNVE 132 Query: 132 ISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFM 191 + V + + + AAI P T+L+W+ETPTNP + DI G A + +L VDNTF Sbjct: 133 YTPVALADLDAVRAAIRPTTRLIWVETPTNPLLSIADIAGIAQLGADSSAKVL-VDNTFA 191 Query: 192 SPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPID 251 SP Q+PL+LGAD+ ++S TKY+ GHSDVV G + N E L FLQN GAVP P D Sbjct: 192 SPALQQPLSLGADVVLHSTTKYIGGHSDVVGGALVTNDEELDQSFAFLQNGAGAVPGPFD 251 Query: 252 CYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCT 311 YL RGLKTL +RM++H +N AVA+FL +P + V+YPGLPSHP H + RQ G Sbjct: 252 AYLTMRGLKTLVLRMQRHSENAAAVAEFLAEHPAISTVLYPGLPSHPGHAVAARQMRGFG 311 Query: 312 GMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISD 371 GMV+ ++ AE +F LAESLG ESL E P+ MTHAS + L + D Sbjct: 312 GMVSVRMRAGRTAAEQLCAKTNIFILAESLGSVESLIEHPSAMTHASTAGSQ---LEVPD 368 Query: 372 TLIRLSVGLEDEEDLLEDLDQAL 394 L+RLSVG+ED DLL+DL QAL Sbjct: 369 DLVRLSVGIEDVADLLDDLKQAL 391 >1CS1-A nrPDB Length = 386 Score = 485 bits (1249), Expect = e-137, Method: Composition-based stats. Identities = 156/382 (40%), Positives = 226/382 (59%), Gaps = 3/382 (0%) Query: 19 ATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAAL 78 AT A+ G + ++ VVPPI LS+T+ + +YSR GNPTR+ +++A+A L Sbjct: 6 ATIAVRSGLNDDEQYG-CVVPPIHLSSTYNFTGFNEPRAHDYSRRGNPTRDVVQRALAEL 64 Query: 79 DGAKYCLAFASGLAATVTITH-LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDC 137 +G + +G++A +T LK GD ++ D YGG+ R F +A ++ FVD Sbjct: 65 EGGAGAVLTNTGMSAIHLVTTVFLKPGDLLVAPHDCYGGSYRLFDSLAKRGCYRVLFVDQ 124 Query: 138 SKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQR 197 + L AA+ + KLV +E+P+NP +V+DI H+ + G + VVDNTF+SP Q Sbjct: 125 GDEQALRAALAEKPKLVLVESPSNPLLRVVDIAKICHLAREVGA-VSVVDNTFLSPALQN 183 Query: 198 PLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNR 257 PLALGAD+ ++S TKY+NGHSDVV G+V + L + N++G D YL R Sbjct: 184 PLALGADLVLHSCTKYLNGHSDVVAGVVIAKDPDVVTELAWWANNIGVTGGAFDSYLLLR 243 Query: 258 GLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFY 317 GL+TL RME +N A+ ++L++ P V+K+ +P LP + HE+ RQ G M++F Sbjct: 244 GLRTLVPRMELAQRNAQAIVKYLQTQPLVKKLYHPSLPENQGHEIAARQQKGFGAMLSFE 303 Query: 318 IKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLS 377 + G Q FL L LFTLAESLGG ESL A MTHA + R GIS+TL+R+S Sbjct: 304 LDGDEQTLRRFLGGLSLFTLAESLGGVESLISHAATMTHAGMAPEARAAAGISETLLRIS 363 Query: 378 VGLEDEEDLLEDLDQALKAAHP 399 G+ED EDL+ DL+ +AA+ Sbjct: 364 TGIEDGEDLIADLENGFRAANK 385 >1PFF-A nrPDB Length = 331 Score = 473 bits (1218), Expect = e-134, Method: Composition-based stats. Identities = 143/329 (43%), Positives = 205/329 (62%), Gaps = 3/329 (0%) Query: 69 NCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 + LE +A L+ A+ C A ASG+ A + LKAGD +I D +YG T+ F + Sbjct: 1 SALEGKIAKLEHAEACAATASGMGAIAASVWTFLKAGDHLISDDCLYGCTHALFEHQLRK 60 Query: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187 FG+++ F+D + +E + P T++V+ ETP NPT KVIDIE K DI+++VD Sbjct: 61 FGVEVDFIDMAVPGNIEKHLKPNTRIVYFETPANPTLKVIDIEDAVKQARKQKDILVIVD 120 Query: 188 NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN-RLRFLQNSLGAV 246 NTF SP PL LG DI ++SATKY+NGH+DVV GLV + + + + +++ GA+ Sbjct: 121 NTFASPILTNPLDLGVDIVVHSATKYINGHTDVVAGLVCSRADIIAKVKSQGIKDITGAI 180 Query: 247 PSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQ 306 SP D +L RG TL +R+++ +N VA+FL + V+KV YPGLP HP HE+ K+Q Sbjct: 181 ISPHDAWLITRGTLTLDMRVKRAAENAQKVAEFLHEHKAVKKVYYPGLPDHPGHEIAKKQ 240 Query: 307 CTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDV 366 M+ F + G L+ A+ L N + +LA SLGG ESL + PA MTHA V K +R+ Sbjct: 241 MKMFGSMIAFDVDG-LEKAKKVLDNCHVVSLAVSLGGPESLIQHPASMTHAGVPKEEREA 299 Query: 367 LGISDTLIRLSVGLEDEEDLLEDLDQALK 395 G++D LIRLSVG E+ +D+++DL QAL Sbjct: 300 AGLTDNLIRLSVGCENVQDIIDDLKQALD 328 >1I43-A nrPDB Length = 445 Score = 451 bits (1161), Expect = e-127, Method: Composition-based stats. Identities = 139/386 (36%), Positives = 224/386 (58%), Gaps = 13/386 (3%) Query: 22 AIHVGQDPEQW-TSRAVVPPISLSTTFKQGAPGQ--------HSGFEYSRSGNPTRNCLE 72 AIH G+ + + A+ P+ ++ + + + FEY R GNPT LE Sbjct: 61 AIHAGERLGRGIVTDAITTPVVNTSAYFFNKTSELIDFKEKRRASFEYGRYGNPTTVVLE 120 Query: 73 KAVAALDGAKYCLAFASGL-AATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLK 131 + ++AL+GA+ L ASG+ A+TV + L+ AG I+ D Y T + + + G+ Sbjct: 121 EKISALEGAESTLLMASGMCASTVMLLALVPAGGHIVTTTDCYRKTRIFIETILPKMGIT 180 Query: 132 ISFVDCSKIKLLEAAITPE-TKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTF 190 + +D + + LE A+ + L + E+PTNP + +DIE + + H+ G ++ +D TF Sbjct: 181 ATVIDPADVGALELALNQKKVNLFFTESPTNPFLRCVDIELVSKLCHEKGALV-CIDGTF 239 Query: 191 MSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPI 250 +P Q+ LALGAD+ ++SATK++ GH+DV+ G +S + L + +R L + LG +P Sbjct: 240 ATPLNQKALALGADLVLHSATKFLGGHNDVLAGCISGPLK-LVSEIRNLHHILGGALNPN 298 Query: 251 DCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGC 310 YL RG+KTLH+R+++ + +A+ LE++P V V YPGL SHP+H + K+Q TG Sbjct: 299 AAYLIIRGMKTLHLRVQQQNSTALRMAEILEAHPKVRHVYYPGLQSHPEHHIAKKQMTGF 358 Query: 311 TGMVTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGIS 370 G V+F + G L F+ LK+ +A S GG ES+ + PAIM++ + ++DR GI Sbjct: 359 GGAVSFEVDGDLLTTAKFVDALKIPYIAPSFGGCESIVDQPAIMSYWDLSQSDRAKYGIM 418 Query: 371 DTLIRLSVGLEDEEDLLEDLDQALKA 396 D L+R S G+ED +DL D+ QAL + Sbjct: 419 DNLVRFSFGVEDFDDLKADILQALDS 444 >4KAM-A nrPDB Length = 453 Score = 446 bits (1148), Expect = e-126, Method: Composition-based stats. Identities = 146/427 (34%), Positives = 221/427 (51%), Gaps = 45/427 (10%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLST--TFKQGAPG------QHSGFEYSRSGNPTRN 69 F T+ IH GQ P+ T+ + PI +T TF+ A + G Y+R GNPT + Sbjct: 22 FETKQIHAGQQPDSATNARAL-PIYQTTSYTFENTAHAAALFGLEVPGNIYTRLGNPTTD 80 Query: 70 CLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 +E+ +AAL+G L +SG AA T I +L AGD I+ +YGGT F ++ Sbjct: 81 VVEQRIAALEGGVAALFLSSGQAAETFAILNLAGAGDHIVSSPRLYGGTYNLFHYSLAKL 140 Query: 129 GLKISFVD-CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187 G+++SFVD + +AA+ P TK + ET +NP ++D G A + H++G I L+VD Sbjct: 141 GIEVSFVDDPDNLDSWQAAVRPNTKAFFGETISNPQIDLLDTPGVAEVAHRNG-IPLIVD 199 Query: 188 NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS--------------------- 226 NT +PY RP GADI ++SATKY+ GH + G++ Sbjct: 200 NTIATPYLIRPFTQGADIVVHSATKYLGGHGAAIAGVIVDGGTFDWTQGRFPEFTTPDPS 259 Query: 227 ----------VNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAV 276 +L R++ L++ LG+ SP + +L +GL+TL +R+E+H N V Sbjct: 260 YHGVVFAELGAPAYALKARVQLLRD-LGSAASPFNAFLVAQGLETLSLRIERHVSNAQRV 318 Query: 277 AQFLESNPWVEKVIYPGLPSHPQHELVKRQC-TGCTGMVTFYIKGTLQHAEIFLKNLKLF 335 A+FL V V Y GLP P HE K+ G +++F + G ++ + F+ LKL Sbjct: 319 AEFLADREDVVTVNYAGLPGSPWHERAKKLSPKGTGAVLSFELAGGVEAGKAFVNALKLH 378 Query: 336 TLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALK 395 + ++G SL PA THA + ++ G+S L+RL+VG+E ED+L DL+ Sbjct: 379 SHVANIGDVRSLVIHPASTTHAQLSPAEQLSTGVSPGLVRLAVGIEGIEDILADLELGFA 438 Query: 396 AAHPPSG 402 AA SG Sbjct: 439 AARKFSG 445 >4U1T-A nrPDB Length = 389 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 158/381 (41%), Positives = 224/381 (58%), Gaps = 7/381 (1%) Query: 15 FQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKA 74 F T+ +H G+ P T VVPPI +STT+++ A + + Y R NPTR LE+ Sbjct: 3 GMRFDTRLVHGGRRPSAGTGD-VVPPIHVSTTYERRAQDEPR-YFYGRGENPTREELEEC 60 Query: 75 VAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISF 134 +A L+ A + F+SG AA T+ L++ G ++ DDVY GT+ F +A+ G+++ + Sbjct: 61 LAGLERAPFATVFSSGQAAAATLLSLVRPGQCVVSTDDVYAGTDGLFD-LAARQGVRVRY 119 Query: 135 VDCSKIKLLEAAI-TPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSP 193 D + + + AA+ P+ LVWIETPTNP V+D+ + H+ G + VVDNTF SP Sbjct: 120 ADLTTPEGIAAALAEPDLALVWIETPTNPLLTVVDVAEVSRRAHERGARV-VVDNTFASP 178 Query: 194 YFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCY 253 Q+PLALGAD+S+YS TK + GH+DV+ G + LH +R + + G VP +DC+ Sbjct: 179 VLQQPLALGADVSLYSTTKSIAGHADVLGGALVYRDADLHAAVRAYRTTAGNVPGALDCF 238 Query: 254 LCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGM 313 L RGL TL +R+ + + + L ++P V V YPGLP HPQH +VK Q + + Sbjct: 239 LVRRGLHTLSLRVHRQVATARVLVERLRASPVVGAVHYPGLPEHPQHAVVKAQMSAPGAI 298 Query: 314 VTFYIKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTL 373 V+F G AE L LFT SLGG SL E PA+MTH + R GI ++L Sbjct: 299 VSFDYLGG--PAERLLDRFTLFTCGVSLGGVHSLVECPALMTHRPLSAEARARRGIGESL 356 Query: 374 IRLSVGLEDEEDLLEDLDQAL 394 IRLSVG+ED +DL EDL +AL Sbjct: 357 IRLSVGIEDPQDLAEDLSRAL 377 >3NDN-A nrPDB Length = 414 Score = 437 bits (1125), Expect = e-123, Method: Composition-based stats. Identities = 125/396 (31%), Positives = 209/396 (52%), Gaps = 16/396 (4%) Query: 12 LPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAP--------GQHSGFEYSRS 63 LP AT + G + A + L++ + G+ G+ + YSR Sbjct: 21 LPDGVSQATVGVRGGMLRSGFEETA--EAMYLTSGYVYGSAAVAEKSFAGELDHYVYSRY 78 Query: 64 GNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYFR 122 GNPT + E+ + ++GA A ASG+AA T + LL AGD+++ ++G Sbjct: 79 GNPTVSVFEERLRLIEGAPAAFATASGMAAVFTSLGALLGAGDRLVAARSLFGSCFVVCS 138 Query: 123 QVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDI 182 ++ +G++ FVD + E A++ T+ V+ ETP+NP Q ++DI + H G Sbjct: 139 EILPRWGVQTVFVDGDDLSQWERALSVPTQAVFFETPSNPMQSLVDIAAVTELAHAAGAK 198 Query: 183 ILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNS 242 + V+DN F +P Q+ LG D+ +YS TK+++G V+ G + + E + ++ L Sbjct: 199 V-VLDNVFATPLLQQGFPLGVDVVVYSGTKHIDGQGRVLGGAILGDREYIDGPVQKLMRH 257 Query: 243 LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHEL 302 G S + ++ +GL+TL +R++ + +A+FL +P V V YP LPSHPQ++L Sbjct: 258 TGPAMSAFNAWVLLKGLETLAIRVQHSNASAQRIAEFLNGHPSVRWVRYPYLPSHPQYDL 317 Query: 303 VKRQCTGCTGMVTFYI----KGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHAS 358 KRQ +G +VTF + Q A L ++L ++ +LG +SL PA TH + Sbjct: 318 AKRQMSGGGTVVTFALDCPEDVAKQRAFEVLDKMRLIDISNNLGDAKSLVTHPATTTHRA 377 Query: 359 VLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394 + R +G+ D ++R+SVGLED +DL+ D+D+AL Sbjct: 378 MGPEGRAAIGLGDGVVRISVGLEDTDDLIADIDRAL 413 >4OC9-A nrPDB Length = 424 Score = 435 bits (1118), Expect = e-122, Method: Composition-based stats. Identities = 127/424 (29%), Positives = 208/424 (49%), Gaps = 52/424 (12%) Query: 19 ATQAIHVGQDPEQWTSRAVVPPISLSTTFK-----QGAPG---QHSGFEYSRSGNPTRNC 70 T A+H + + T R++ PI +T + Q A Q G YSR NPT + Sbjct: 7 ETLALHGAYNFD--TQRSISVPIYQNTAYNFENLDQAAARFNLQELGNIYSRLSNPTSDV 64 Query: 71 LEKAVAALDGAKYCLAFASGLAATV-TITHLLKAGDQIICMDDVYGGTNRYFRQVASEFG 129 L + +A ++G + + ASG+AA + +L +GD + + +YGGT FG Sbjct: 65 LGQRLANVEGGAFGIPVASGMAACFYALINLASSGDNVAYSNKIYGGTQTLISHTLKNFG 124 Query: 130 LKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNT 189 ++ D + LE I TK ++ E+ +NP + DIE I KH I+ + DNT Sbjct: 125 IEAREFDIDDLDSLEKVIDQNTKAIFFESLSNPQIAIADIEKINQIAKKH-KIVSICDNT 183 Query: 190 FMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLR------------ 237 +P+ +P G D+ ++S +KY++G + G + + L++ L+ Sbjct: 184 VATPFLLQPFKHGVDVIVHSLSKYVSGQGTALGGALI-ERKDLNDLLKNNDRYKAFNTPD 242 Query: 238 -----------------------FLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGM 274 +L++ LGA +P + +L +GL+TL VR+EKH +N Sbjct: 243 PSYHGLNLNTLDLPIFSIRVIITWLRD-LGASLAPQNAWLLLQGLETLAVRIEKHSQNAE 301 Query: 275 AVAQFLESNPWVEKVIYPGLPSHPQHELVKRQC--TGCTGMVTFYIKGTLQHAEIFLKNL 332 VA FL S+P ++ V YP L S+ H L K+ +G+++F K +HA Sbjct: 302 KVANFLNSHPDIKGVNYPTLASNAYHNLFKKYFDKNFASGLLSFEAK-DYEHARRICDKT 360 Query: 333 KLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQ 392 +LF LA +LG +SL PA TH+ + + + GI+ IRLS+GLE+ +DL+ DL Q Sbjct: 361 QLFLLAANLGDSKSLIIHPASTTHSQLSEEELQKAGITKATIRLSIGLENSDDLIADLKQ 420 Query: 393 ALKA 396 A+++ Sbjct: 421 AIES 424 >2CTZ-A nrPDB Length = 421 Score = 432 bits (1110), Expect = e-121, Method: Composition-based stats. Identities = 134/421 (31%), Positives = 206/421 (48%), Gaps = 45/421 (10%) Query: 17 HFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHS--------GFEYSRSGNPTR 68 F T +H G +PE T PI +T++ +P + G YSR NPT Sbjct: 2 RFETLQLHAGYEPEPTTLSR-QVPIYPTTSYVFKSPEHAANLFALKEFGNIYSRIMNPTV 60 Query: 69 NCLEKAVAALDGAKYCLAFASGLAATV-TITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 + LEK +AAL+G K LA ASG AA +T L +AGD I+ ++YGGT F+ Sbjct: 61 DVLEKRLAALEGGKAALATASGHAAQFLALTTLAQAGDNIVSTPNLYGGTFNQFKVTLKR 120 Query: 128 FGLKISFVDCSKIKLLEAAIT-PETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVV 186 G+++ F + A+T +T+ W+E+ NP + D+E A + G + L+V Sbjct: 121 LGIEVRFTSREERPEEFLALTDEKTRAWWVESIGNPALNIPDLEALAQAAREKG-VALIV 179 Query: 187 DNTF-MSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS------------------- 226 DNTF M Y RPLA GA + +S TK++ GH V+ G + Sbjct: 180 DNTFGMGGYLLRPLAWGAALVTHSLTKWVGGHGAVIAGAIVDGGNFPWEGGRYPLLTEPQ 239 Query: 227 -----VNCESLHNRLRFLQNSL-------GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGM 274 + L F+ + G P + ++ G++TL +R E+H +N + Sbjct: 240 PGYHGLRLTEAFGELAFIVKARVDGLRDQGQALGPFEAWVVLLGMETLSLRAERHVENTL 299 Query: 275 AVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTG-CTGMVTFYIKGTLQHAEIFLKNLK 333 +A +L P V V YPGLP HP H+ ++ G ++TF +KG + A+ F+ LK Sbjct: 300 HLAHWLLEQPQVAWVNYPGLPHHPHHDRAQKYFKGKPGAVLTFGLKGGYEAAKRFISRLK 359 Query: 334 LFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQA 393 L + ++G +LA PA TH+ + ++ G+S ++RLSVGLE EDL +L +A Sbjct: 360 LISHLANVGDTRTLAIHPASTTHSQLSPEEQAQAGVSPEMVRLSVGLEHVEDLKAELKEA 419 Query: 394 L 394 L Sbjct: 420 L 420 >5IJG-A nrPDB Length = 427 Score = 414 bits (1064), Expect = e-116, Method: Composition-based stats. Identities = 139/408 (34%), Positives = 216/408 (52%), Gaps = 38/408 (9%) Query: 14 HFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTF------------------KQGAPGQH 55 H H TQ ++ G D E + AV PP+ L++TF K+ G Sbjct: 14 HLLHPETQMLNYGYDSE-LSEGAVKPPVFLTSTFVFKTAEDGRDFFDFVSGRKEPPAGVG 72 Query: 56 SGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVY 114 +G YSR +P +E +A +GA+ F+SG++A T + ++ GD I+ +Y Sbjct: 73 AGLVYSRFNHPNSEIVEDRLAVYEGAESAALFSSGMSAIATTLFAFVRPGDVILHSQPLY 132 Query: 115 GGTNRYFRQVASEFGLK-ISFVDCSKIKLLEAAITP-----ETKLVWIETPTNPTQKVID 168 GGT + FG++ ++F D +E A ++ IETP NPT ++D Sbjct: 133 GGTETLLAKTFFNFGVEAVAFADGVHEATIEKAAEEALAKGRVSVILIETPANPTNSIVD 192 Query: 169 IEGCAHIV-----HKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMG 223 + + + ++ DNT + P FQ+PL GAD+S+YS TKY+ GHSD++ G Sbjct: 193 VAAVRRVAEKIEARQGSRPVIACDNTLLGPVFQKPLDHGADLSVYSLTKYVGGHSDLIAG 252 Query: 224 LVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESN 283 V + +S+ +++ L+ ++G P C++ R L+TL +RME+ N A+A+FL ++ Sbjct: 253 AV-LGAKSVVRQVKALRGAIGTQLDPHSCWMLGRSLETLGLRMERADSNARAIAEFLRNH 311 Query: 284 PWVEKVIYPGLPSHPQH----ELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAE 339 P VEK+ Y LP + L KRQCTG +F IKG A FL L++ LA Sbjct: 312 PKVEKLHY--LPFADERSDIAALFKRQCTGAGSTFSFDIKGGQAAAFRFLNALQILKLAV 369 Query: 340 SLGGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLL 387 SLGG ESLA PA MTH+ V + R+ +G+ ++ IRLS+G+E +DL+ Sbjct: 370 SLGGTESLASHPAAMTHSGVPVDVRERIGVLESTIRLSIGIEHPDDLI 417 >3RI6-A nrPDB Length = 430 Score = 412 bits (1059), Expect = e-115, Method: Composition-based stats. Identities = 137/413 (33%), Positives = 214/413 (51%), Gaps = 32/413 (7%) Query: 11 FLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFK--------QGAPGQHSGFEYSR 62 F H + F T+A+HV + ++ A+ P+ + F+ Q + G+ G YSR Sbjct: 20 FQGHMRGFTTRALHVPK-AKRDVHGALRTPVYDNAAFEFENSDEIAQVSLGRALGHVYSR 78 Query: 63 SGNPTRNCLEKAVAALDGAKYCLAFASGLAATVT-ITHLLKAGDQIICMDDVYGGTNRYF 121 S NPT LE+ + L GA LA SG+AA T I L +AGD ++ D ++G T F Sbjct: 79 SSNPTVEDLEQRLKNLTGALGVLALGSGMAAISTAILTLARAGDSVVTTDRLFGHTLSLF 138 Query: 122 RQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 ++ FG+++ FVD +E A TKL+++ET +NP +V D+E + +VH G Sbjct: 139 QKTLPSFGIEVRFVDVMDSLAVEHACDETTKLLFLETISNPQLQVADLEALSKVVHAKG- 197 Query: 182 IILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVS----VNCESLHN--- 234 I LVVD T PY LG DI + S+TK+++G V G++ +SL + Sbjct: 198 IPLVVDTTMTPPYLLEAKRLGVDIEVLSSTKFISGGGTSVGGVLIDHGLFEWKSLPSLAP 257 Query: 235 ------RLRFLQNS-------LGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLE 281 + FL + LG SP + YL + GL+T+ +R+E+ +N +A +L Sbjct: 258 YYAKAGPMAFLYKARKEVFQNLGPSLSPHNAYLQSLGLETMALRIERSCQNAQELAHWLL 317 Query: 282 SNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESL 341 S P V+ V +P LP P + + KRQ ++TF ++ + + F+ LKL A ++ Sbjct: 318 SIPQVKCVNHPSLPDSPFYAIAKRQFRYAGSILTFELESK-EASYRFMDALKLIRRATNI 376 Query: 342 GGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394 +SL P + +A +R L IS ++RLSVG+E+ EDL ED+ QAL Sbjct: 377 HDNKSLILSPYHVIYALNSHEERLKLEISPAMMRLSVGIEEIEDLKEDILQAL 429 >2FQ6-A nrPDB Length = 415 Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats. Identities = 124/405 (30%), Positives = 209/405 (51%), Gaps = 26/405 (6%) Query: 10 GFLPHFQHFA-----TQAIHVGQDPEQWTSRAVVPPISLSTTF-------KQGAPGQHSG 57 G +P H A TQ ++ G+ +++T AV I +++ K+ A + Sbjct: 13 GLVPRGSHMADKKLDTQLVNAGRS-KKYTLGAVNSVIQRASSLVFDSVEAKKHATRNRAN 71 Query: 58 FE--YSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATV-TITHLLKAGDQIICMDDVY 114 E Y R G T L++A+ L+G C+ F G AA +I ++ GD ++ + Y Sbjct: 72 GELFYGRRGTLTHFSLQQAMCELEGGAGCVLFPCGAAAVANSILAFIEQGDHVLMTNTAY 131 Query: 115 GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAH 174 + + ++ S+ G+ S+ D + + P TK+V++E+P + T +V D+ Sbjct: 132 EPSQDFCSKILSKLGVTTSWFDPLIGADIVKHLQPNTKIVFLESPGSITMEVHDVPAIVA 191 Query: 175 IVHKH-GDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLH 233 V D I+++DNT+ + + L G D+S+ +ATKY+ GHSD ++G N Sbjct: 192 AVRSVVPDAIIMIDNTWAAGVLFKALDFGIDVSIQAATKYLVGHSDAMIGTAVCNARCW- 250 Query: 234 NRLRFLQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPG 293 +LR +G + Y+ +RGL+TL VR+ +H ++ + VA++L +P V +V +P Sbjct: 251 EQLRENAYLMGQMVDADTAYITSRGLRTLGVRLRQHHESSLKVAEWLAEHPQVARVNHPA 310 Query: 294 LPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEI--FLKNLKLFTLAESLGGFESLA--E 349 LP HE KR TG +G+ +F +K L + E+ +L N LF++A S GG+ESL Sbjct: 311 LPGSKGHEFWKRDFTGSSGLFSFVLKKKLNNEELANYLDNFSLFSMAYSWGGYESLILAN 370 Query: 350 LPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQAL 394 P H + ++ + + S TLIRL +GLED +DL+ DLD Sbjct: 371 QP---EHIAAIRPQGE-IDFSGTLIRLHIGLEDVDDLIADLDAGF 411 >2CB1-A nrPDB Length = 412 Score = 369 bits (948), Expect = e-102, Method: Composition-based stats. Identities = 126/415 (30%), Positives = 200/415 (48%), Gaps = 42/415 (10%) Query: 18 FATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHS-------GFEYSRSGNPTRNC 70 + T A+ G + AV PI + + G+ Y+R +PT Sbjct: 3 YTTLAVLAGLPEDPH--GAVGLPIYAVAAYGFKTLEEGQERFATGEGYVYARQKDPTAKA 60 Query: 71 LEKAVAALDGAKYCLAFASGLAATVTITHLL-KAGDQIICMDDVYGGTNRYFRQVASEFG 129 LE+ + AL+GA + ASG AAT L + GD+++ ++G T F QV S G Sbjct: 61 LEERLKALEGALEAVVLASGQAATFAALLALLRPGDEVVAAKGLFGQTIGLFGQVLSLMG 120 Query: 130 LKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNT 189 + + +VD + + A++ +T+ V++ET NP V D+E A + + G + LVVDNT Sbjct: 121 VTVRYVDPE-PEAVREALSAKTRAVFVETVANPALLVPDLEALATLAEEAG-VALVVDNT 178 Query: 190 F-MSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV-SVNCESLHNRLRFLQNSL---- 243 F + RPLA GA + + S TK+ +GH V+ G V S E N +FLQ L Sbjct: 179 FGAAGALCRPLAWGAHVVVESLTKWASGHGSVLGGAVLSRETELWRNYPQFLQPDLKGQI 238 Query: 244 ----------------------GAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLE 281 G SP + YL +GL+T+ +R+ + + +A+ L+ Sbjct: 239 PWEALRARCFPERVRTLGLSLCGMALSPFNAYLLFQGLETVALRVARMSETARFLAERLQ 298 Query: 282 SNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLKLFTLAESL 341 +P V+ + YPGLP P H ++ ++T + G L+ A FL ++L A +L Sbjct: 299 GHPKVKALRYPGLPEDPAHRNARKYLASGGPILTLDL-GDLERASRFLGAIRLLK-AANL 356 Query: 342 GGFESLAELPAIMTHASVLKNDRDVLGISDTLIRLSVGLEDEEDLLEDLDQALKA 396 G +L P TH+ + + R G++ L+R+SVGLED DLL ++AL+A Sbjct: 357 GDARTLLVHPWTTTHSRLKEEARLQAGVTPGLVRVSVGLEDPLDLLALFEEALEA 411 >1V2E-A nrPDB Length = 381 Score = 86.5 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 49/220 (22%), Positives = 85/220 (38%), Gaps = 44/220 (20%) Query: 5 DASSQGFLPHFQHFATQ--AIHVGQD-----PEQWTSRAVVPPISLSTTFKQGAPGQHSG 57 +A+ + P A + A+++GQ P + AV + + G + Sbjct: 8 EAAKESIFPRMSGLAQRLGAVNLGQGFPSNPPPPFLLEAVRRALGRQDQYA-PPAGLPA- 65 Query: 58 FEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGL--AATVTITHLLKAGDQIICMD---D 112 R L + A + SG A V + L+ GD+++ ++ D Sbjct: 66 ---------LREALAEEFAV---EPESVVVTSGATEALYVLLQSLVGPGDEVVVLEPFFD 113 Query: 113 VY-------GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQK 165 VY G R R + G ++ + LE A+TP T+ + + TP NPT Sbjct: 114 VYLPDAFLAGAKARLVRLDLTPEGFRL------DLSALEKALTPRTRALLLNTPMNPTGL 167 Query: 166 VI---DIEGCAHIVHKHGDIILVVDNTFMSPYF-QRPLAL 201 V ++E A + H D+ L+ D + Y+ +RP L Sbjct: 168 VFGERELEAIARLARAH-DLFLISDEVYDELYYGERPRRL 206 >3NYS-A nrPDB Length = 367 Score = 61.9 bits (149), Expect = 6e-10, Method: Composition-based stats. Identities = 46/190 (24%), Positives = 75/190 (39%), Gaps = 24/190 (12%) Query: 66 PTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLL--KAGDQIICMDDVYGGTNRYFRQ 123 P LE +A GAKYC++ A+G A + L GD++I G T + Sbjct: 35 PEVTELEDRLADFVGAKYCISCANGTDALQIVQMALGVGPGDEVITP----GFTYVATAE 90 Query: 124 VASEFGLKISFVDCS------KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 177 + G K +VD +LLEAAITP TK + P + + D + I Sbjct: 91 TVALLGAKPVYVDIDPRTYNLDPQLLEAAITPRTKAII---PVSLYGQCADFDAINAIAS 147 Query: 178 KHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY-----MNGHSDVVMGLVSVNCESL 232 K+G I ++ D + ++S + T + + + D G + N + L Sbjct: 148 KYG-IPVIEDAAQSFGASYKGKR-SCNLSTVACTSFFPSAPLGCYGD--GGAIFTNDDEL 203 Query: 233 HNRLRFLQNS 242 +R + Sbjct: 204 ATAIRQIARH 213 >1M6S-A nrPDB Length = 347 Score = 61.5 bits (148), Expect = 6e-10, Method: Composition-based stats. Identities = 73/356 (20%), Positives = 118/356 (33%), Gaps = 67/356 (18%) Query: 51 APGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIIC 109 A + Y +PT N LE+ A G + L SG + V+I + GD++I Sbjct: 25 AQAEVGDDVYG--EDPTINELERLAAETFGKEAALFVPSGTMGNQVSIMAHTQRGDEVIL 82 Query: 110 MDDV----YG-GTNRYFRQVAS-----EFGLKISFVDCSKIKLLEAAIT------PETKL 153 D Y G V + G + AI P T L Sbjct: 83 EADSHIFWYEVGAMAVLSGVMPHPVPGKNG-------AMDPDDVRKAIRPRNIHFPRTSL 135 Query: 154 VWIETPTNPTQK----VIDIEGCAHIVHKHG-----DIILVVDNTFMSPYFQRPLALGAD 204 + IE N + + +I+ I +HG D + + + S + A AD Sbjct: 136 IAIENTHNRSGGRVVPLENIKEICTIAKEHGINVHIDGARIFNASIASGVPVKEYAGYAD 195 Query: 205 ISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG---LKT 261 M+ +K + +G V V R R + LG L G L Sbjct: 196 SVMFCLSKGLC----APVGSVVVGDRDFIERARKARKMLGGGMR-QAGVLAAAGIIALTK 250 Query: 262 LHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGT 321 + R+++ +N +A L+ + + T MV Sbjct: 251 MVDRLKEDHENARFLALKLKEI---------------GYSVNPEDVK--TNMVILRTDNL 293 Query: 322 LQHAEIFLKNLKLF-TLAESLGGFESLAELPAIMTHASVLKND-RDVLGISDTLIR 375 +A F++ L+ LA ++ E +TH V +ND + L I + L R Sbjct: 294 KVNAHGFIEALRNSGVLANAVSDTEIRL-----VTHKDVSRNDIEEALNIFEKLFR 344 >3UWC-A nrPDB Length = 374 Score = 59.9 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 45/186 (24%), Positives = 77/186 (41%), Gaps = 23/186 (12%) Query: 69 NCLEKAVAALDGAKYCLAFASGLAATVTITHLL--KAGDQIICMDDVYGGTNRYFRQVAS 126 EK AAL A + + +G A +L AGD++I + + + Q Sbjct: 41 EKFEKRFAALHNAPHAIGVGTGTDALAMSFKMLNIGAGDEVITCANTFIASVGAIVQA-- 98 Query: 127 EFGLKISFVDCS-----KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 G VD + +EAAIT +TK + P + T + D+ A I KH + Sbjct: 99 --GATPVLVDSENGYVIDPEKIEAAITDKTKAIM---PVHYTGNIADMPALAKIAKKH-N 152 Query: 182 IILVVD--NTFMSPYFQRPL-ALG--ADISMYSATKYMNGHSDVVMGLVSVNCESLHNRL 236 + +V D T + + + + G A S++ K +N SD G++ + + +L Sbjct: 153 LHIVEDACQTILGRINDKFVGSWGQFACFSLHPL-KNLNVWSD--AGVIITHSDEYAEKL 209 Query: 237 RFLQNS 242 R +N Sbjct: 210 RLYRNH 215 >3OP7-A nrPDB Length = 375 Score = 59.2 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 44/219 (20%), Positives = 82/219 (37%), Gaps = 29/219 (13%) Query: 92 AATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS-------KIKLLE 144 A + + L++ GD +I +Y T + + G ++ ++ L Sbjct: 93 ANLLVLYSLIEPGDHVIS---LY-PTYQQLYDIPKSLGAEVDLWQIEEENGWLPDLEKLR 148 Query: 145 AAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTFMS------PYF 195 I P TK++ I NPT V+D +E I + G IL D + S P Sbjct: 149 QLIRPTTKMICINNANNPTGAVMDRTYLEELVEIASEVGAYIL-SDEVYRSFSELDVPSI 207 Query: 196 QRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLC 255 G ++ S T + G + +G V+ N + + + LR ++ D + Sbjct: 208 IEVYDKGIAVNSLSKTYSLPG---IRIGWVAANHQ-VTDILRDYRDYTMICAGVFDDLVA 263 Query: 256 NRGLKTLHVRMEKH----FKNGMAVAQFLESNPWVEKVI 290 L +E++ +N + Q++E P V + Sbjct: 264 QLALAHYQEILERNRHILEENLAILDQWIEEEPLVSYIR 302 >2Z61-A nrPDB Length = 370 Score = 55.7 bits (133), Expect = 3e-08, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 70/170 (41%), Gaps = 20/170 (11%) Query: 88 ASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAI 147 S L ++ ++ GD+++ + Y + R G K F D + ++ LE A+ Sbjct: 97 GSSLGLFFALSSIIDDGDEVLIQNPCYPCYKNFIRF----LGAKPVFCDFT-VESLEEAL 151 Query: 148 TPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQ----RPLALGA 203 + +TK + I +P+NP +VID +++ ++ D + ++ + Sbjct: 152 SDKTKAIIINSPSNPLGEVID-REIYEFAYEN-IPYIISDEIYNGLVYEGKCYSAIEFDE 209 Query: 204 DISMYSATKYMNGHSDVVM------GLVSVNCESLHNRLRFLQNSLGAVP 247 ++ T +NG S + G V N E + L+ QN + P Sbjct: 210 NLE---KTILINGFSKLYAMTGWRIGYVISNDEIIEAILKLQQNLFISAP 256 >1YIY-A nrPDB Length = 429 Score = 54.5 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 40/154 (25%), Positives = 61/154 (39%), Gaps = 29/154 (18%) Query: 62 RSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMD---DVY---- 114 R+ NP L V A + A TI + GD++I ++ D Y Sbjct: 96 RTINPMTEVL-VTVGAYE------------ALYATIQGHVDEGDEVIIIEPFFDCYEPMV 142 Query: 115 ---GGTNRYFRQVASEFGLKISFVD-CSKIKLLEAAITPETKLVWIETPTNPTQKVID-- 168 GG R+ ++ G IS D LEA +TK++ I TP NP KV+D Sbjct: 143 KAAGGIPRFIPLKPNKTGGTISSADWVLDNNELEALFNEKTKMIIINTPHNPLGKVMDRA 202 Query: 169 -IEGCAHIVHKHGDIILVVDNTFMSPYFQRPLAL 201 +E A++ K +++ V D + P Sbjct: 203 ELEVVANLCKK-WNVLCVSDEVY-EHMVFEPFEH 234 >2OGE-A nrPDB Length = 399 Score = 54.5 bits (130), Expect = 8e-08, Method: Composition-based stats. Identities = 42/190 (22%), Positives = 69/190 (36%), Gaps = 26/190 (13%) Query: 66 PTRNCLEKAVAALDGAKYCLAFASGL-AATVTITHL-LKAGDQIICMDDVYGGTNRYFRQ 123 P E AA + + SG+ A + + L + GD++I ++ Y Sbjct: 63 PELEGFEAEFAAYCETDHAVGVNSGMDALQLALRGLGIGPGDEVIVP------SHTYIAS 116 Query: 124 VA--SEFGLKISFVDC------SKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 175 S G V+ L+E AITP T+ + P + D++ + Sbjct: 117 WLAVSATGATPVPVEPHEDHPTLDPLLVEKAITPRTRALL---PVHLYGHPADMDALREL 173 Query: 176 VHKHGDIILVVDNTFMSPYFQRPLALGADISMYSAT----KYMNGHSDVVMGLVSVNCES 231 +HG + +V D R +GA S+ + + K + D G V Sbjct: 174 ADRHG-LHIVEDAAQAHGARYRGRRIGAGSSVAAFSFYPGKNLGCFGD--GGAVVTGDPE 230 Query: 232 LHNRLRFLQN 241 L RLR L+N Sbjct: 231 LAERLRMLRN 240 >2GB3-A nrPDB Length = 409 Score = 54.1 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 39/182 (21%), Positives = 75/182 (41%), Gaps = 21/182 (11%) Query: 82 KYCLAFASGLAAT-VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDC--- 137 + L G A + + GD+I+ ++ Y F ++A G+K+ V Sbjct: 103 ENVLVTNGGSEAILFSFAVIANPGDEILVLEPFY-ANYNAFAKIA---GVKLIPVTRRME 158 Query: 138 ---SKIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTFM 191 + + LE+ I TK + + P NPT V ++ I +HG + L+VD + Sbjct: 159 EGFAIPQNLESFINERTKGIVLSNPCNPTGVVYGKDEMRYLVEIAERHG-LFLIVDEVYS 217 Query: 192 SPYFQ----RPLALGAD--ISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGA 245 F+ L++ +D + + S +K + V L++ N E + + ++ Q L Sbjct: 218 EIVFRGEFASALSIESDKVVVIDSVSKKFSACGARVGCLITRNEELISHAMKLAQGRLAP 277 Query: 246 VP 247 Sbjct: 278 PL 279 >1O4S-A nrPDB Length = 389 Score = 52.2 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 36/197 (18%), Positives = 69/197 (35%), Gaps = 43/197 (21%) Query: 91 LAATVTITHLLKAGDQIICMDDVY----------GGTNRYFRQVASEFGLKISFVDCSKI 140 A LL GD++I V+ GGT S+ S + Sbjct: 112 QALFNAFMALLDPGDEVIVFSPVWVSYIPQIILAGGTVNVVETFMSKN------FQPS-L 164 Query: 141 KLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTFMSPYFQR 197 + +E + +TK V I +P NPT V +EG + K + ++ D + S + Sbjct: 165 EEVEGLLVGKTKAVLINSPNNPTGVVYRREFLEGLVRLAKKR-NFYIISDEVYDSLVYTD 223 Query: 198 PL------ALGADISM--------YSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSL 243 + G D + +S T + G+ ++ E + + +Q+ Sbjct: 224 EFTSILDVSEGFDRIVYINGFSKSHSMTGWRVGY--------LISSEKVATAVSKIQSHT 275 Query: 244 GAVPSPIDCYLCNRGLK 260 + + + Y + L+ Sbjct: 276 TSCINTVAQYAALKALE 292 >1J32-A nrPDB Length = 388 Score = 51.8 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 46/119 (38%), Gaps = 21/119 (17%) Query: 80 GAKYCLAFASGLAATVTI-THLLKAGDQIICMDD----------VYGGTNRYFRQVASEF 128 GA L G + + +++ GD++I + GT Sbjct: 89 GADNILVTNGGKQSIFNLMLAMIEPGDEVIIPAPFWVSYPEMVKLAEGTPVILPTT---- 144 Query: 129 GLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIIL 184 ++ F + + AITP+TKL+ TP+NPT V ++ A + + G +L Sbjct: 145 -VETQF--KVSPEQIRQAITPKTKLLVFNTPSNPTGMVYTPDEVRAIAQVAVEAGLWVL 200 >2ZJG-A nrPDB Length = 410 Score = 51.5 bits (122), Expect = 8e-07, Method: Composition-based stats. Identities = 35/149 (23%), Positives = 58/149 (38%), Gaps = 29/149 (19%) Query: 57 GFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGG 116 G Y R +P E+ + A+ Y F S I L+ GD++I M Y Sbjct: 75 GKIYQRQIDPN----EEILVAV--GAYGSLFNS-------IQGLVDPGDEVIIMVPFYDC 121 Query: 117 TNRYFR-----------QVASEFGLKISFVD-CSKIKLLEAAITPETKLVWIETPTNPTQ 164 R + G+K + D + LE+ + +TK + + TP NP Sbjct: 122 YEPMVRMAGAVPVFIPLRSKPTDGMKWTSSDWTFDPRELESKFSSKTKAIILNTPHNPLG 181 Query: 165 KVI---DIEGCAHIVHKHGDIILVVDNTF 190 KV +++ A + KH D + + D + Sbjct: 182 KVYTRQELQVIADLCVKH-DTLCISDEVY 209 >3CAI-A nrPDB Length = 406 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 65/176 (36%), Gaps = 14/176 (7%) Query: 44 STTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGA-KYCLAFASGLAATVTITHLLK 102 ST F++ +R + +AVA L A + + A +++ Sbjct: 47 STAFRRSGASTVGAHPSARRSAAVLDAAREAVADLVNADPGGVVLGADRAVLLSLLAEAS 106 Query: 103 A-----GDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIK------LLEAAITPET 151 + G ++I + + A +G K+ + + E+ I+ T Sbjct: 107 SSRAGLGYEVIVSRLDDEANIAPWLRAAHRYGAKVKWAEVDIETGELPTWQWESLISKST 166 Query: 152 KLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPY-FQRPLALGADIS 206 +LV + + + V D+ +VH G ++ VVD++ +PY AD+ Sbjct: 167 RLVAVNSASGTLGGVTDLRAMTKLVHDVGALV-VVDHSAAAPYRLLDIRETDADVV 221 >1U08-A nrPDB Length = 386 Score = 50.7 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 25/105 (23%), Positives = 42/105 (40%), Gaps = 8/105 (7%) Query: 92 AATVTITHLLKAGDQIICMD---DVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAIT 148 A IT L++ GD++IC D D Y + L+ + A ++ Sbjct: 103 ALYAAITALVRNGDEVICFDPSYDSYAPAIALSGGIVKRMALQPPHF-RVDWQEFAALLS 161 Query: 149 PETKLVWIETPTNPTQKV---IDIEGCAHIVHKHGDIILVVDNTF 190 T+LV + TP NP+ V D + H +I ++ D + Sbjct: 162 ERTRLVILNTPHNPSATVWQQADFAALWQAIAGH-EIFVISDEVY 205 >5TXT-B nrPDB Length = 491 Score = 50.3 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 32/149 (21%), Positives = 56/149 (37%), Gaps = 14/149 (9%) Query: 66 PTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAG--DQIICMDDVYGGTNRYFRQ 123 PT N LE +A L + L F+S A + LL D +I D++ + Sbjct: 102 PTLN-LEAELATLHKKEGALVFSSCYVANDAVLSLLGQKMKDLVIFSDEL---NHASMIV 157 Query: 124 VASEFGLKISFVDCSKIKLLEAAIT--PE--TKLVWIETPTNPTQKVIDIEGCAHIVHKH 179 +K + + LE + P+ KL+ E+ + V DIE + K+ Sbjct: 158 GIKHANVKKHIFKHNDLNELEQLLQSYPKSVPKLIAFESVYSMAGSVADIEKICDLADKY 217 Query: 180 GDIILVVDNTFMSPYFQRPLALGADISMY 208 G + +D + GA ++ + Sbjct: 218 GAL-TFLDEVHAVGLYG---PHGAGVAEH 242 >1MDZ-A nrPDB Length = 393 Score = 50.3 bits (119), Expect = 2e-06, Method: Composition-based stats. Identities = 44/200 (22%), Positives = 78/200 (39%), Gaps = 28/200 (14%) Query: 66 PTRNCLEKAVAALDGAKYCLAFASGLAAT-VTITHL-LKAGDQIICMDDVYGGTNRYFRQ 123 P LE A L G +Y +A +S A + + L + GD++I + T Sbjct: 39 PKNQELEAAFCRLTGNQYAVAVSSATAGMHIALMALGIGEGDEVITPSMTWVSTLNMI-- 96 Query: 124 VASEFGLKISFVDCS------KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 177 G VD + +EAAITP+TK + P + D++ + Sbjct: 97 --VLLGANPVMVDVDRDTLMVTPEHIEAAITPQTKAII---PVHYAGAPADLDAIYALGE 151 Query: 178 KHGDIILVVDNTFMSPYFQRPLALGA---DISMYSATKYMNGHSDVVMGLVSVNCESLHN 234 ++G I ++ D + + +GA I + A K + + G+V + + Sbjct: 152 RYG-IPVIEDAAHATGTSYKGRHIGARGTAIFSFHAIKNI---TCAEGGIVVTDNPQFAD 207 Query: 235 RLRFLQ-NSLGAVPSPIDCY 253 +LR L+ + LG D + Sbjct: 208 KLRSLKFHGLGV-----DAW 222 >4BMK-A nrPDB Length = 442 Score = 49.1 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 48/234 (20%), Positives = 81/234 (34%), Gaps = 24/234 (10%) Query: 61 SRSGNPT---RNCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIICMDDVYGG 116 SR N T +E+A+ G + F++G +A I+ L G+ +I D + Sbjct: 123 SRMLNGTFHDHMEVEQALRDFYGTTGAIVFSTGYMANLGIISTLAGKGEYVILDADSHAS 182 Query: 117 TNRYFRQVASEFGLKISFVDCSKIKL-LEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 175 +Q +E ++ + L KLV +E + + ++ + Sbjct: 183 IYDGCQQGNAEI-VRFRHNSVEDLDKRLGRLPKEPAKLVVLEGVYSMLGDIAPLKEMVAV 241 Query: 176 VHKHGDIILVVDNT----FMSP-----YFQRPLALGADISMYSATKYMNGHSDVVMGLVS 226 KHG ++L VD F P Y + L D + + + + V G V Sbjct: 242 AKKHGAMVL-VDEAHSMGFFGPNGRGVYEAQGLEGQIDFVVGTFSASVG----TVGGFVV 296 Query: 227 VNCESLHN-RLRFLQNSLGAVPSPI---DCYLCNRGLKTLHVRMEKHFKNGMAV 276 N RL A P R L T H + E+ + N A+ Sbjct: 297 SNHPKFEAVRLACRPYIFTASLPPSVVATATTSIRKLMTAHEKRERLWSNARAL 350 >5W70-A nrPDB Length = 445 Score = 49.1 bits (116), Expect = 3e-06, Method: Composition-based stats. Identities = 42/191 (21%), Positives = 76/191 (39%), Gaps = 28/191 (14%) Query: 73 KAVAALDGAKYCLAFASGLAATVTITHL--LKAGDQIICMDDVYGGTNRYFRQVASEFGL 130 +A AA +G +C+ ASG A+ + + AGD++I + ++ G+ Sbjct: 80 RAFAAYNGVPHCVPAASGTASLMLALEACGIGAGDEVIVPG------LSWVASGSTILGV 133 Query: 131 KISF----VDCSK----IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDI 182 VD + +EAAIT T+ + + + + D++ + I +HG + Sbjct: 134 NAVPIFCDVDPDTLCLSPEAVEAAITEHTRAIVVVHLYS---ALADMDALSAIAERHG-L 189 Query: 183 ILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVV----MGLVSVNCESLHNRLRF 238 L+ D R + +GA + +A + HS V+ G V E R+ Sbjct: 190 PLIEDCAQAHGATYRGVKVGA---LATAGTFSMQHSKVLTSGEGGAVITRDEDFARRVEH 246 Query: 239 LQNSLGAVPSP 249 L+ G S Sbjct: 247 LRAD-GRCLSA 256 >3B46-A nrPDB Length = 447 Score = 48.8 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 46/185 (24%), Positives = 71/185 (38%), Gaps = 40/185 (21%) Query: 97 ITHLLKAGDQIICMDDVYGGTNRYFRQVASEF---GLKISFVDCSKIKLL---------- 143 + LL AGD++I + +F Q G K+ +V + K L Sbjct: 135 LMGLLNAGDEVIVFEP-------FFDQYIPNIELCGGKVVYVPINPPKELDQRNTRGEEW 187 Query: 144 -------EAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTFMSP 193 E AIT +TK V I TP NP KV ++ +I KH +++++ D + Sbjct: 188 TIDFEQFEKAITSKTKAVIINTPHNPIGKVFTREELTTLGNICVKH-NVVIISDEVYEHL 246 Query: 194 YFQRPLALGADIS---------MYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLG 244 YF A +S + SA K + ++S+N E L + Sbjct: 247 YFTDSFTRIATLSPEIGQLTLTVGSAGKSFAATGWRIGWVLSLNAELLSYAAKAHTRICF 306 Query: 245 AVPSP 249 A PSP Sbjct: 307 ASPSP 311 >3LVM-A nrPDB Length = 423 Score = 48.8 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 72/366 (19%), Positives = 113/366 (30%), Gaps = 71/366 (19%) Query: 46 TFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGA-KYCLAFASG------LAATVTIT 98 TF A H + + +A L GA + F SG LA Sbjct: 51 TFGNPASRSHR---FGWQAEEAVDIARNQIADLVGADPREIVFTSGATESDNLAIKGAAN 107 Query: 99 HLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS-----KIKLLEAAITPETKL 153 K G II + RQ G +++++ +K LEAA+ +T L Sbjct: 108 FYQKKGKHIITSKTEHKAVLDTCRQ-LEREGFEVTYLAPQRNGIIDLKELEAAMRDDTIL 166 Query: 154 VWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALG---ADISMYSA 210 V I N V DI + G II VD T P+ L D+ +S Sbjct: 167 VSIMHVNNEIGVVQDIAAIGEMCRARG-IIYHVDATQSVGKL--PIDLSQLKVDLMSFSG 223 Query: 211 TKYMNGHSDVVMGLVSVNCES---LHNRLRFLQNSLG---------AVPSPIDCYLCNRG 258 K +G + V + + ++ + G + + Y + Sbjct: 224 HKIYGPKG---IGALYVRRKPRVRIEAQMHGGGHERGMRSGTLPVHQIVGMGEAYRIAK- 279 Query: 259 LKTLHVRMEKHFKNGMAVAQFL-ESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFY 317 + + ME+ + L +E+V G H G ++ Sbjct: 280 -EEMATEMER----LRGLRNRLWNGIKDIEEVYLNGDLEH-----------GAPNILNVS 323 Query: 318 IKGTLQHAEIFLKNLKLFTLAESLGGFESLAELPAIMTHASVLKNDRDVLGISDTL---- 373 E + LK LA S G A + + LG++D L Sbjct: 324 F--NYVEGESLIMALK--DLAVSSGS--------ACTSASLEPSYVLRALGLNDELAHSS 371 Query: 374 IRLSVG 379 IR S+G Sbjct: 372 IRFSLG 377 >3W1J-A nrPDB Length = 392 Score = 48.4 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 44/225 (19%), Positives = 86/225 (38%), Gaps = 34/225 (15%) Query: 71 LEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVY---GGTNRYFRQVASE 127 +EK + L GA+ + A + + L G ++I GG+ R + + Sbjct: 63 IEKYLNELTGAESSFVVNNNAGAVFLVLNTLAEGKEVIISRGELVEIGGSFR-IPDIMKK 121 Query: 128 FGL---KISFVDCSKIKLLEAAITPETKLVWIETPTN----PTQKVIDIEGCAHIVHKHG 180 G ++ + +K+ E AI T L+ +N + + +E + HK+G Sbjct: 122 SGAILREVGTTNKTKVSDYEGAINQNTALLMKVHKSNFYMEGFVEEVKLEDLVKLGHKYG 181 Query: 181 DIILVVDN-------------TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSV 227 I D + P F+ ++LG D+ S K + G G++ Sbjct: 182 -IPTYYDAGSGLLINLKEFGISVDEPNFRDCISLGIDLVSGSGDKLLGGPQ---AGIIVG 237 Query: 228 NCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLK-TLHVRMEKHFK 271 ++L +++ +N + L GL+ TL + EK ++ Sbjct: 238 K-KNLIEKIK--KNPIARALRIDK--LTLSGLEMTLKLYFEKRYE 277 >3W1H-A nrPDB Length = 452 Score = 48.4 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 44/225 (19%), Positives = 86/225 (38%), Gaps = 34/225 (15%) Query: 71 LEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVY---GGTNRYFRQVASE 127 +EK + L GA+ + A + + L G ++I GG+ R + + Sbjct: 123 IEKYLNELTGAESSFVVNNNAGAVFLVLNTLAEGKEVIISRGELVEIGGSFR-IPDIMKK 181 Query: 128 FGL---KISFVDCSKIKLLEAAITPETKLVWIETPTN----PTQKVIDIEGCAHIVHKHG 180 G ++ + +K+ E AI T L+ +N + + +E + HK+G Sbjct: 182 SGAILREVGTTNKTKVSDYEGAINQNTALLMKVHKSNFYMEGFVEEVKLEDLVKLGHKYG 241 Query: 181 DIILVVDN-------------TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSV 227 I D + P F+ ++LG D+ S K + G G++ Sbjct: 242 -IPTYYDAGSGLLINLKEFGISVDEPNFRDCISLGIDLVSGSGDKLLGGPQ---AGIIVG 297 Query: 228 NCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLK-TLHVRMEKHFK 271 ++L +++ +N + L GL+ TL + EK ++ Sbjct: 298 K-KNLIEKIK--KNPIARALRIDK--LTLSGLEMTLKLYFEKRYE 337 >1GC4-A nrPDB Length = 385 Score = 48.4 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 26/112 (23%), Positives = 41/112 (36%), Gaps = 19/112 (16%) Query: 91 LAATVTITHLLKAGDQIICMDDV---------YGGTNRYFRQVASEFGLKISFVDCSKIK 141 A +L GD++I + + G + E G + Sbjct: 102 QALFNLFQAILDPGDEVIVLSPYWVSYPEMVRFAGGVVVEVETLPEEGF------VPDPE 155 Query: 142 LLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTF 190 + AITP TK + + +P NPT V +E A + +H D LV D + Sbjct: 156 RVRRAITPRTKALVVNSPNNPTGAVYPKEVLEALARLAVEH-DFYLVSDEIY 206 >5K8B-A nrPDB Length = 403 Score = 47.6 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 50/246 (20%), Positives = 90/246 (36%), Gaps = 33/246 (13%) Query: 67 TRNCLEKAVAALDGAKYCLAFASGLAA--TVTITHLLKAGDQIICMDDVYGGT-NRYFRQ 123 TR+ +E+ + K+ +SG AA T + + AGD++I + + F Sbjct: 39 TRD-MEQLLCEKMNVKHAHLLSSGTAALQTAMMAAGIGAGDEVIVPPFTFVASVEAIFMA 97 Query: 124 VASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDII 183 A +I C + +EA ITP TK + + K+ +I+ K +++ Sbjct: 98 GAVPIFAEIDETLCLSPEGIEAVITPRTKAINLVHMCGSMAKMDEIKAIC----KKHNLV 153 Query: 184 LVVDNTFMSPYFQRPLALGA--DISMYS--ATKYMNGHSDVVMGLVSVNCESLHNRLRFL 239 L+ D + ALG D+ YS + K + G V N +++ Sbjct: 154 LLEDACQAIGGSYKGQALGTIGDVGCYSFDSVKTITCGE---GGAVITNNTEIYDNAHMF 210 Query: 240 ----QNSLGA--------------VPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLE 281 + +G S ++ L L+ L ++ KN A+ + Sbjct: 211 SDHGHDHIGKDRGAESHPIMGLNFRISEMNAALGLAQLRKLDTIIDIQRKNKKAIKDAMA 270 Query: 282 SNPWVE 287 S P V Sbjct: 271 SIPEVS 276 >3DR4-A nrPDB Length = 391 Score = 47.2 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 74/201 (36%), Gaps = 36/201 (17%) Query: 70 CLEKAVAALDGAKYCLAFASGLAATVTITHL--LKAGDQIICMDDVY----------GGT 117 EKA A G K+ +A +G A + GD++I Y G T Sbjct: 60 EFEKAFADYCGVKHAIACNNGTTALHLALVAMGIGPGDEVIVPSLTYIASANSVTYCGAT 119 Query: 118 NRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH 177 F L LEA ITP TK + P + ++ D++ + Sbjct: 120 PVLVDNDPRTFNL--------DAAKLEALITPRTKAIM---PVHLYGQICDMDPILEVAR 168 Query: 178 KHGDIILVVDNTFMSPYFQRPLALGA--DISMYSATKYMNGHSDVV---MGLVSVNCESL 232 +H +++++ D R G+ D + +S G++ + G+++ N + L Sbjct: 169 RH-NLLVIEDAAEAVGATYRGKKSGSLGDCATFS----FFGNAIITTGEGGMITTNDDDL 223 Query: 233 HNRLRFLQNSLGAVPSPIDCY 253 ++R L+ G P Y Sbjct: 224 AAKMRLLR---GQGMDPNRRY 241 >5YHV-A nrPDB Length = 394 Score = 46.8 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 37/175 (21%), Positives = 57/175 (32%), Gaps = 39/175 (22%) Query: 59 EYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTN 118 +Y R T AV G+ A AGD++ Y Sbjct: 86 DYQRRHGITVEP--DAVVITTGSSGGFLLA--------FLACFDAGDRVAMASPGYPC-- 133 Query: 119 RYFRQVASEFGLKISFVDCSK------IKLLEAAITPETKLVWIETPTNPTQKVIDIEGC 172 +R + S G ++ + C + A I P + V + +P NPT VI E Sbjct: 134 --YRNILSALGCEVVEIPCGPQTRFQPTAQMLAEIDPPLRGVVVASPANPTGTVIPPEEL 191 Query: 173 AHIVH--KHGDIILVVDNTFMSPYFQRPLALGA------------DISMYSATKY 213 A I D+ L+ D + +Q GA + + S +KY Sbjct: 192 AAIASWCDASDVRLISDEVYHGLVYQ-----GAPQTSCAWQTSRNAVVVNSFSKY 241 >4WP0-A nrPDB Length = 472 Score = 46.4 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 45/219 (20%), Positives = 76/219 (34%), Gaps = 44/219 (20%) Query: 39 PPISLSTTFKQGAPGQHSGFEYSRSGN--PTRNCLEKAVAALDGAK-----YCLAFASGL 91 PP F+ G +Y+++ P L L G + L G Sbjct: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 Query: 92 AATVT-ITHLLKAGDQIICMD---DVY------GGTNRYFRQVAS------EFGLKISFV 135 A T L+ GD++I ++ D Y G F + E G ++ Sbjct: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW- 160 Query: 136 DCSKIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF-- 190 L T TK + + TP NP KV ++E A + +H D++ + D + Sbjct: 161 -QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQW 218 Query: 191 -------------MSPYFQRPLALGADISMYSATKYMNG 216 + ++R L +G+ +SAT + G Sbjct: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 >3FVS-A nrPDB Length = 422 Score = 46.4 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 45/219 (20%), Positives = 76/219 (34%), Gaps = 44/219 (20%) Query: 39 PPISLSTTFKQGAPGQHSGFEYSRSGN--PTRNCLEKAVAALDGAK-----YCLAFASGL 91 PP F+ G +Y+++ P L L G + L G Sbjct: 42 PPDFAVEAFQHAVSGDFMLNQYTKTFGYPPLTKILASFFGELLGQEIDPLRNVLVTVGGY 101 Query: 92 AATVT-ITHLLKAGDQIICMD---DVY------GGTNRYFRQVAS------EFGLKISFV 135 A T L+ GD++I ++ D Y G F + E G ++ Sbjct: 102 GALFTAFQALVDEGDEVIIIEPFFDCYEPMTMMAGGRPVFVSLKPGPIQNGELGSSSNW- 160 Query: 136 DCSKIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF-- 190 L T TK + + TP NP KV ++E A + +H D++ + D + Sbjct: 161 -QLDPMELAGKFTSRTKALVLNTPNNPLGKVFSREELELVASLCQQH-DVVCITDEVYQW 218 Query: 191 -------------MSPYFQRPLALGADISMYSATKYMNG 216 + ++R L +G+ +SAT + G Sbjct: 219 MVYDGHQHISIASLPGMWERTLTIGSAGKTFSATGWKVG 257 >2O0R-A nrPDB Length = 411 Score = 46.4 bits (109), Expect = 2e-05, Method: Composition-based stats. Identities = 30/189 (15%), Positives = 68/189 (35%), Gaps = 27/189 (14%) Query: 92 AATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVD-----CSKIKLLEAA 146 A + L++ G +++ ++ Y + +A + + V L A Sbjct: 98 AIAAAVLGLVEPGSEVLLIEPFYD-SYSPVVAMAGAHRVTVPLVPDGRGFALDADALRRA 156 Query: 147 ITPETKLVWIETPTNPTQKVIDIEGC--AHIVHKHGDIILVVDNTFMSPYFQRPLAL--- 201 +TP T+ + I +P NPT V+ + +++++ D + F L Sbjct: 157 VTPRTRALIINSPHNPTGAVLSATELAAIAEIAVAANLVVITDEVYEHLVFDHARHLPLA 216 Query: 202 GAD------ISMYSATK----------YMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGA 245 G D I++ SA K + G ++++ G+ + + Q ++ Sbjct: 217 GFDGMAERTITISSAAKMFNCTGWKIGWACGPAELIAGVRAAKQYLSYVGGAPFQPAVAL 276 Query: 246 VPSPIDCYL 254 D ++ Sbjct: 277 ALDTEDAWV 285 >5XT5-A nrPDB Length = 419 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 47/116 (40%), Gaps = 6/116 (5%) Query: 83 YCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV----DCS 138 + + A LK GD+++ + ++Q G + ++ D + Sbjct: 93 KGTTTSLNMVALSYARANLKPGDEVVITYMEHHANIIPWQQAVKATGATLKYIPLQEDGT 152 Query: 139 K-IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSP 193 ++ + +T TK+V + +N V I+ A I H +G ++VVD +P Sbjct: 153 ISLEDVRETVTSNTKIVAVSHVSNVLGTVNPIKEMAKIAHDNGA-VIVVDGAQSTP 207 >4PIW-A nrPDB Length = 396 Score = 46.1 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 43/183 (23%), Positives = 71/183 (38%), Gaps = 28/183 (15%) Query: 71 LEKAVAALDGAKYCLAFASGLAAT--VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEF 128 LE+ G+ L S A+ + ++ GD++I + T F V Sbjct: 60 LEQRF----GSAKVLLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAF--VLR-- 111 Query: 129 GLKISFVDC------SKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDI 182 G KI FVD L+EAAIT +T+++ P + +++ + KH ++ Sbjct: 112 GAKIVFVDVRPDTMNIDETLIEAAITDKTRVI---VPVHYAGVACEMDTIMALAKKH-NL 167 Query: 183 ILVVDNT--FMSPYFQRPLALGADI---SMYSATKYMNGHSDVVMGLVSVNCESLHNRLR 237 +V D MS Y R L I S + Y G G +N ++L R Sbjct: 168 FVVEDAAQGVMSTYKGRALGTIGHIGCFSFHETKNYTAGGE---GGATLINDKALIERAE 224 Query: 238 FLQ 240 ++ Sbjct: 225 IIR 227 >1XI9-A nrPDB Length = 406 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 27/128 (21%), Positives = 49/128 (38%), Gaps = 14/128 (10%) Query: 92 AATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSK----IKLLEAAI 147 A + LL GD+I+ Y + ++ ++ I + I Sbjct: 113 ALQLIFGALLDPGDEILVPGPSYPPYTGLV-KFYGGKPVEYRTIEEEDWQPDIDDIRKKI 171 Query: 148 TPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGAD 204 T TK + + P NPT + D +E +I ++ +I ++ D + ++ G Sbjct: 172 TDRTKAIAVINPNNPTGALYDKKTLEEILNIAGEY-EIPVISDEIYDLMTYE-----GEH 225 Query: 205 ISMYSATK 212 IS S TK Sbjct: 226 ISPGSLTK 233 >1GDE-A nrPDB Length = 389 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 26/138 (18%), Positives = 59/138 (42%), Gaps = 19/138 (13%) Query: 68 RNCLEKAVAALDGAKY------CLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYF 121 R + + + +G + + + A + ++ LK G++++ + Y Sbjct: 69 REAIAEKLKKQNGIEADPKTEIMVLLGANQAFLMGLSAFLKDGEEVLIPTPAF---VSYA 125 Query: 122 RQVASEFG--LKISFVDCS----KIKLLEAAITPETKLVWIETPTNPTQKVI---DIEGC 172 V G +++ + + L+ +T +T+ + I +P NPT V+ D+E Sbjct: 126 PAVILAGGKPVEVPTYEEDEFRLNVDELKKYVTDKTRALIINSPCNPTGAVLTKKDLEEI 185 Query: 173 AHIVHKHGDIILVVDNTF 190 A V +H D+I++ D + Sbjct: 186 ADFVVEH-DLIVISDEVY 202 >4MY5-A nrPDB Length = 393 Score = 45.7 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 24/112 (21%), Positives = 46/112 (41%), Gaps = 15/112 (13%) Query: 92 AATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDC------SKIKLLEA 145 A + ++T +L+ GD+++ Y G + V + G ++ +D ++LE Sbjct: 105 ALSASLTAILEPGDKVLLPAPAYPG----YEPVVNLVGAEVVEIDTRSNDFVLTPEMLEE 160 Query: 146 AI---TPETKLVWIETPTNPTQKVIDIEGCAHIVH--KHGDIILVVDNTFMS 192 AI K V + PTNPT + ++ K I ++ D + Sbjct: 161 AILKEGEALKAVILNYPTNPTGVTYSRQQIKNLAEVLKKYPIFVISDEVYAE 212 >5HH9-A nrPDB Length = 390 Score = 45.3 bits (106), Expect = 4e-05, Method: Composition-based stats. Identities = 49/290 (16%), Positives = 95/290 (32%), Gaps = 54/290 (18%) Query: 87 FASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKIS----FVDC----- 137 GLAA L++ G +I+ + T G ++ F D Sbjct: 85 TTDGLAAIYGGL-LVQPGKEILTSSHEHYSTYTTLEYRHKRMGTQVREFPLFKDPHRVSA 143 Query: 138 -SKIKLLEAAITPETKLV---WIETPTNPTQKVIDIEGCAHIVH----KHGDIILVVDNT 189 + + A I P+T+++ W+++ + + +I ++ + II VVD Sbjct: 144 DEILSSIAAQIRPQTRVLGMTWVQSGSGVKLPIREIGKLVRELNQKRDEQDRIIYVVDGV 203 Query: 190 FMSPYFQRPL-ALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLR------FLQNS 242 D + K++ G G++ E L L ++ Sbjct: 204 HGFGVEDVSFADFDCDYFIAGTHKWLFGPRGT--GVIIARSEQLQEHLVPSIPTFSRADN 261 Query: 243 LGAVPSP--IDCYLCNRGLKT---LHVRM-------EKHFKNGMAVAQFLESNPWVEKVI 290 G + +P + L T LH+++ H N + Q L +P V V Sbjct: 262 FGTLMTPGGYHAFEHRLALGTAFELHLQLGKAEVQARIHQLNA-YLKQRLGEHPKVRLVT 320 Query: 291 YPGLPSHPQHELVKRQCTGCTGMVTFYIKG-TLQHAEIFLKNLKLFTLAE 339 P+ P+ +G F ++G + L ++ + A Sbjct: 321 ----PTSPE---------LSSGFTFFRVEGRDCEAVAKHLMAHRVISDAV 357 >5WMH-A nrPDB Length = 475 Score = 44.9 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 28/134 (20%), Positives = 56/134 (41%), Gaps = 11/134 (8%) Query: 68 RNCLEKAVAALDGAKYC---LAFASG--LAATVTITHLLKAGDQIICMDDV---YGGTNR 119 R + + + +G Y + ++G + + + GD++I Y R Sbjct: 142 REAICRKLKEENGLSYAPDQILVSNGAKQSLLQAVLAVCSPGDEVIIPAPYWVSYTEQAR 201 Query: 120 YFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIV 176 KIS K LE+ +T +++L+ + +P+NPT V +E A I+ Sbjct: 202 LADATPVVIPTKISNNFLLDPKDLESKLTEKSRLLILCSPSNPTGSVYPKSLLEEIARII 261 Query: 177 HKHGDIILVVDNTF 190 KH ++++ D + Sbjct: 262 AKHPRLLVLSDEIY 275 >3L8A-A nrPDB Length = 421 Score = 44.5 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 40/171 (23%), Positives = 63/171 (36%), Gaps = 28/171 (16%) Query: 92 AATVTITHLLKAGDQIICMDDVY---GGTNRYFRQVASEFGLKI--SFVDCSKIKLLEAA 146 A ++ + + GD ++ VY T R E L+I + +L + Sbjct: 131 AISIALQAFSEKGDAVLINSPVYYPFARTIRLNDHRLVENSLQIINGRFEIDFEQLEKDI 190 Query: 147 ITPETKLVWIETPTNPTQKV---IDIEGCAHIVHKHGDIILVVD----------NTFMSP 193 I K+ + +P NP +V D+ A + KHG +ILV D NT S Sbjct: 191 IDNNVKIYLLCSPHNPGGRVWDNDDLIKIAELCKKHG-VILVSDEIHQDLALFGNTHHSL 249 Query: 194 YFQRPLALGADISMYSATKYMNGHSDVVMGL----VSVNCESLHNRLRFLQ 240 I + SATK N + G + ESL + ++ Q Sbjct: 250 NTLDASYKDFTIILSSATKTFN-----IAGTKNSFAIIQNESLRRKFQYRQ 295 >2DOU-A nrPDB Length = 376 Score = 44.1 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 46/244 (18%), Positives = 86/244 (35%), Gaps = 34/244 (13%) Query: 67 TRNCLEKAVAALDGA---------KYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGT 117 T LE+A +G + S + L + D ++ + Y Sbjct: 65 TLPFLEEAARWYEGRYGVGLDPRREALALIGSQEGLAHLLLALTEPEDLLLLPEVAYPSY 124 Query: 118 NRYFRQ-VASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVID---IEGCA 173 R F + + + +K + + E K++ + P NPT V D E Sbjct: 125 FGAARVASLRTFLIPLREDGLADLKAVPEGVWREAKVLLLNYPNNPTGAVADWGYFEEAL 184 Query: 174 HIVHKHGDIILVVDNTFMSPYFQ----RPLAL-GAD---ISMYSATKYMNGHSDVVMGLV 225 + KHG + L+ DN ++ ++ PLAL GA + ++S +K N + G Sbjct: 185 GLARKHG-LWLIHDNPYVDQVYEGEAPSPLALPGAKERVVELFSLSKSYN-----LAGFR 238 Query: 226 SVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTL-----HVR--MEKHFKNGMAVAQ 278 L L+ G + + G++ L VR + + + +A+ Sbjct: 239 LGFALGSEEALARLERVKGVIDFNQYAGVLRMGVEALKTPKEVVRGYARVYRERALGMAE 298 Query: 279 FLES 282 L+ Sbjct: 299 ALKG 302 >6F35-A nrPDB Length = 410 Score = 43.7 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 51/127 (40%), Gaps = 20/127 (15%) Query: 77 ALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVA----------S 126 A + + +A + + L GD++I Y + + + Sbjct: 98 AYELDEITVATGAKQILFNAMMASLDPGDEVIIPTP-YWTSYSDIVHICEGKPVLIACDA 156 Query: 127 EFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQ---KVIDIEGCAHIVHKHGDII 183 G +++ + LEAAITP T+ V + +P+NP+ D ++ +H + Sbjct: 157 SSGFRLT------AEKLEAAITPRTRWVLLNSPSNPSGAAYSAADYRPLLEVLLRHPHVW 210 Query: 184 LVVDNTF 190 L+VD+ + Sbjct: 211 LLVDDMY 217 >3WGB-A nrPDB Length = 341 Score = 42.6 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 46/245 (18%), Positives = 84/245 (34%), Gaps = 29/245 (11%) Query: 65 NPTRNCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIICMDD--VYG----GT 117 +P N LE A L G + L SG ++ + + + G+ + +Y G+ Sbjct: 38 DPGVNALEAYGADLLGKEAALFVPSGTMSNLLAVMSHCQRGEGAVLGSAAHIYRYEAQGS 97 Query: 118 NRYFRQVASEFGLKISFVDCSKIKLLEAAITPE------TKLVWIETPTN-PTQKVIDIE 170 ++ + + AAI P+ T+LV +E N + + Sbjct: 98 AVLGSVALQPVPMQAD--GSLALADVRAAIAPDDVHFTPTRLVCLENTHNGKVLPLPYLR 155 Query: 171 GCAHIVHKHG-----DIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLV 225 +V +HG D + + S + R L D +K + +G + Sbjct: 156 EMRELVDEHGLQLHLDGARLFNAVVASGHTVRELVAPFDSVSICLSKGLG----APVGSL 211 Query: 226 SVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTLH---VRMEKHFKNGMAVAQFLES 282 V + R R L+ +G L GL L VR+ + +A+ L + Sbjct: 212 LVGSHAFIARARRLRKMVGGGMR-QAGILAQAGLFALQQHVVRLADDHRRARQLAEGLAA 270 Query: 283 NPWVE 287 P + Sbjct: 271 LPGIR 275 >4ZWV-A nrPDB Length = 372 Score = 42.2 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 49/256 (19%), Positives = 92/256 (35%), Gaps = 41/256 (16%) Query: 66 PTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAG---DQIICMDDVYGGTNRYFR 122 P E A+AA G ++ SG + LL A D+++ + T Sbjct: 33 PRVAEFESALAARLGNPRVVSVHSGTSGLCLALRLLDAPEERDEVLSTPLTFEAT----N 88 Query: 123 QVASEFGLKISFVDCS------KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIV 176 G +I++VD + LE I+P T+ + + T + + G Sbjct: 89 WAILADGRRITWVDVDPATLTMDLDDLERKISPATRAIIVVHWTGYPVDLDRLAGILDRA 148 Query: 177 -HKHGDIILVV-DNTFMSPYFQRPLALGAD--ISMYS--ATKYMNGHSDVVMGLVSVNCE 230 +HG V+ D R + LG+ + ++S A K++ D GL+++ + Sbjct: 149 EREHGFRPAVIEDCAHAWGASYRGVPLGSHGNMCVFSFQALKHLTC-GD--GGLLTLPGD 205 Query: 231 SLHNRLRFLQ---------NSLGAV----------PSPIDCYLCNRGLKTLHVRMEKHFK 271 LH R + GA + ++ + L+T+ ++ H + Sbjct: 206 ELHERAMLRRFYGIDRTADRLRGAYDVAEWGLKWHMTDLNAAIGLANLETVDEQLRLHRE 265 Query: 272 NGMAVAQFLESNPWVE 287 N + L P +E Sbjct: 266 NAAFYDKELTGVPGLE 281 >4Q75-A nrPDB Length = 429 Score = 42.2 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 37/153 (24%), Positives = 58/153 (37%), Gaps = 10/153 (6%) Query: 93 ATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV-----DCSKIKLLEAAI 147 A LK GD++I + ++ V+ + G + FV + I L I Sbjct: 117 AYSWGLSNLKPGDEVILTVAEHHSCIVPWQIVSQKTGAVLKFVTLNEDEVPDINKLRELI 176 Query: 148 TPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSP-YFQRPLALGADIS 206 +P+TKLV + +N + IE H G +L VD P L AD Sbjct: 177 SPKTKLVAVHHVSNVLASSLPIEEIVVWAHDVGAKVL-VDACQSVPHMVVDVQKLNADFL 235 Query: 207 MYSATKYMNGHSDVVMGLVSVNCESLHNRLRFL 239 + S+ K +G + + LH+ FL Sbjct: 236 VASSHKMCGPTG---IGFLYGKSDLLHSMPPFL 265 >6BLG-A nrPDB Length = 379 Score = 42.2 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 41/174 (23%), Positives = 65/174 (37%), Gaps = 24/174 (13%) Query: 80 GAKYCLAFASGLAAT--VTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDC 137 G L S A+ + ++ GD++I + T F V G KI FVD Sbjct: 48 GTAKALLTPSCTASLEMAALLLDIQPGDEVIMPSYTFVSTANAF--VLR--GAKIVFVDI 103 Query: 138 ------SKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNT-- 189 L+EAAIT +T+ + P + +++ I K+ ++ +V D Sbjct: 104 RRDTMNIDETLIEAAITDKTRAI---VPVHYAGVACEMDTIMAIADKY-NLFVVEDAAQG 159 Query: 190 FMSPYFQRPLALGADI---SMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQ 240 MS Y R L I S + Y G G +N +L R ++ Sbjct: 160 VMSTYKGRALGTIGHIGCFSFHETKNYTAGGE---GGATLINDRTLVERAEIIR 210 >2AEV-A nrPDB Length = 374 Score = 41.8 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 58/152 (38%), Gaps = 14/152 (9%) Query: 130 LKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIE---GCAHIVHKHGDIILVV 186 + + + K+ + I +T ++ + + KVI++E + I+ V Sbjct: 121 VNAKYFESDKVGEILNKIDKDTLVIITGSTMD--LKVIELENFKKVINTAKNKEAIVFVD 178 Query: 187 DNTFMS--PYFQRP--LALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNS 242 D + F +P L LGAD+ + S K M G G + + L +++ Sbjct: 179 DASGARVRLLFNQPPALKLGADLVVTSTDKLMEGPR----GGLLAGKKELVDKIYIEGTK 234 Query: 243 LGAVPSPIDCYLCNRGLKTLHV-RMEKHFKNG 273 G P R LK ++ R+ K F+ Sbjct: 235 FGLEAQPPLLAGIYRALKNFNLERIRKAFERA 266 >4W91-A nrPDB Length = 422 Score = 41.8 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 23/110 (20%), Positives = 41/110 (37%), Gaps = 12/110 (10%) Query: 81 AKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSK- 139 A +A+ G+ + GD+I+ + + + G K+ F Sbjct: 113 AINTVAYGYGM-------PFIGEGDEILLSIMEHHSNIVPWHFIRERQGAKLVFTPVDDN 165 Query: 140 ----IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 I+ E ++ TKLV I +N V+ I+ + H G +LV Sbjct: 166 GVFHIEEFEKRLSERTKLVAITHMSNTLGTVVPIKKIVELAHARGIPVLV 215 >1T3I-A nrPDB Length = 420 Score = 41.8 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 24/90 (26%), Positives = 42/90 (46%), Gaps = 5/90 (5%) Query: 101 LKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS-----KIKLLEAAITPETKLVW 155 LKAGD+II + ++ VA++ G + FV ++ + ++ +TKLV Sbjct: 115 LKAGDEIITTVMEHHSNLVPWQMVAAKTGAVLKFVQLDEQESFDLEHFKTLLSEKTKLVT 174 Query: 156 IETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 + +N V E A + H+ G +LV Sbjct: 175 VVHISNTLGCVNPAEEIAQLAHQAGAKVLV 204 >6HRH-B nrPDB Length = 469 Score = 41.4 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 47/235 (20%), Positives = 79/235 (33%), Gaps = 31/235 (13%) Query: 68 RNCLEKAVAALDGAKYCLAFASGLAAT-VTITHLLK--AGDQIICMDDVYGGTNRYFRQV 124 LE+ +A L L F+S A T+ L K G +I G + Q Sbjct: 118 HVELEQELAELHQKDSALLFSSCFVANDSTLFTLAKILPGCEIYSD----AGNHASMIQG 173 Query: 125 ASEFG---LKISFVDCSKIKLLEAAITPE-TKLVWIETPTNPTQKVIDIEGCAHIVHKHG 180 G D +K L P+ K+V ET + + +E + H++G Sbjct: 174 IRNSGAAKFVFRHNDPDHLKKLLEKSNPKIPKIVAFETVHSMDGAICPLEELCDVSHQYG 233 Query: 181 DIILVVDNTFMSPYF-QRPLALGA-DISMY-----SATKYMNGHSDVVMGLVSVNCESLH 233 + VD + R +G D M+ S T + V G ++ L Sbjct: 234 AL-TFVDEVHAVGLYGSRGAGIGERDGIMHKIDIISGT--LGKAFGCVGGYIAS-TRDLV 289 Query: 234 NRLRFLQ------NSLGAVP--SPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFL 280 + +R SL + ++ +G + +R H +N + Q L Sbjct: 290 DMVRSYAAGFIFTTSLPPMVLSGALESVRLLKGEEGQALR-RAHQRNVKHMRQLL 343 >3EUC-A nrPDB Length = 367 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 34/249 (13%), Positives = 79/249 (31%), Gaps = 30/249 (12%) Query: 11 FLPHFQHFATQAIHVGQDPEQWTS---RAVVPPISLSTTFKQGAPGQHSGFEYSRSGNPT 67 + +A+ P+ A+ P L + + +R P+ Sbjct: 9 LIERIIRDDVRAMGAYHVPDSHGLVKLDAMENPYRLPPALRSELAARLGEVALNRYPVPS 68 Query: 68 RNCLEKAVAALDGAKYC--LAFASGLAATVTITHLL--KAGDQIICMDD---VYGGTNRY 120 L + + + +G +++ L + G +++ +Y + ++ Sbjct: 69 SEALRAKLKEVMQVPAGMEVLLGNGSDEIISMLALAAARPGAKVMAPVPGFVMYAMSAQF 128 Query: 121 FRQVASEFGLKISFVDCSKIKLLEAAITP-ETKLVWIETPTNPTQKVIDIEGCAHIVHKH 179 L+ F + AA+ + +V++ P NPT + D IV Sbjct: 129 AGLEFVGVPLRADF--TLDRGAMLAAMAEHQPAIVYLAYPNNPTGNLFDAADMEAIVRAA 186 Query: 180 GDII----LVVDNTF----MSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCES 231 + +VVD + + R G + M + +K +GL + Sbjct: 187 QGSVCRSLVVVDEAYQPFAQESWMSRLTDFGNLLVMRTVSK---------LGLAGIRLGY 237 Query: 232 LHNRLRFLQ 240 + ++L+ Sbjct: 238 VAGDPQWLE 246 >3WY7-A nrPDB Length = 404 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 35/186 (18%), Positives = 63/186 (33%), Gaps = 13/186 (6%) Query: 68 RNCLEKAVAALDGAKYCLAFASGLAA-TVTITHLLKAGDQIICMDDVYGGTNRYFRQVAS 126 E +A+ GA+ L F+SG A + L G I+ + R S Sbjct: 104 HEAFEHQLASFLGAESALVFSSGYTANLGALVALSGPGSLIVSDALSHASLVDACR--LS 161 Query: 127 EFGLKISFVDCSKIKLLEAAITPETKLVWI-ETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 + +S A E + V + E+ + + + + +HG ++LV Sbjct: 162 RARVVVSPHRDVDAVDAALAARTEERAVVVTESVFSADGDLAPLRDLHAVCRRHGALLLV 221 Query: 186 -------VDNTFMSPYFQRPLALGA-DISMYSA-TKYMNGHSDVVMGLVSVNCESLHNRL 236 V T GA DI M + +K + V+G +V + Sbjct: 222 DEAHGLGVRGTRGQGLLHEVGLAGAPDIVMTTTLSKALGSQGGAVLGPEAVRAHLIDTAR 281 Query: 237 RFLQNS 242 F+ ++ Sbjct: 282 SFIFDT 287 >1BW0-A nrPDB Length = 416 Score = 41.1 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 43/123 (34%), Gaps = 17/123 (13%) Query: 85 LAFASG--LAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKL 142 + SG + IT + AGD + + + V +G+ + F +C Sbjct: 107 VVLCSGGSHGILMAITAICDAGDYALVPQPGFPH----YETVCKAYGIGMHFYNCRPEND 162 Query: 143 LEAAITP-------ETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTFMS 192 EA + +TKL+ + P+NP +E + + + L D + Sbjct: 163 WEADLDEIRRLKDDKTKLLIVTNPSNPCGSNFSRKHVEDIVRLAEEL-RLPLFSDEIYAG 221 Query: 193 PYF 195 F Sbjct: 222 MVF 224 >4OTL-A nrPDB Length = 423 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 50/225 (22%), Positives = 86/225 (38%), Gaps = 36/225 (16%) Query: 29 PEQWTSRAVVPP--ISLSTTFKQGAPGQH--SGFEYSRSGNPTRNCLEK----AVAALDG 80 E +TS AV+ L+ + +G PG+ G EY + +E+ V L G Sbjct: 44 SENYTSPAVMAAQGSQLTNKYAEGYPGKRYYGGCEY-------VDVVEQLAIDRVKQLFG 96 Query: 81 AKYC-LAFASG-LAATVTITHLLKAGDQIICMDDVYGG--TNRYFRQVASEFGLKISF-- 134 A+ + SG A +LK GD I+ M +GG T+ ++ ++ +S+ Sbjct: 97 AEAANVQPNSGSQANQGVFFAMLKPGDTIMGMSLAHGGHLTHGSPVNMSGKWFNVVSYGL 156 Query: 135 ---VDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD---- 187 D + A + KL+ + + K+ D E A I G L+VD Sbjct: 157 NENEDIDYDAAEKLANEHKPKLI-VAGASAFALKI-DFERLAKIAKSVGA-YLMVDMAHY 213 Query: 188 -NTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCES 231 + + P+ AD + K + G G++ + E Sbjct: 214 AGLIAAGVYPNPVPH-ADFVTTTTHKSLRGPR---GGVILMKAEY 254 >2O1B-A nrPDB Length = 404 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 61/261 (23%), Positives = 86/261 (32%), Gaps = 55/261 (21%) Query: 7 SSQGFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNP 66 + QG + HFQ T PE A FKQ Y R N Sbjct: 61 TPQGIIDHFQKALTI-------PENQKYGA----FHGKEAFKQAIVD-----FYQRQYNV 104 Query: 67 TRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVAS 126 T + E V L G K L T ++ GD ++ D Y Y V Sbjct: 105 TLDK-EDEVCILYGTKNGL--------VAVPTCVINPGDYVLLPDPGY---TDYLAGVLL 152 Query: 127 EFG--LKISFVDCSKIKLLEAA---ITPETKLVWIETPTNPTQK-----VIDIEGCAHIV 176 G + ++ + I +TKL+++ P NPT V D E A Sbjct: 153 ADGKPVPLNLEPPHYLPDWSKVDSQIIDKTKLIYLTYPNNPTGSTATKEVFD-EAIAKF- 210 Query: 177 HKHGDIILVVDNTFMSPYF----QRPLAL----GADIS--MYSATKYMNGHSDVVMGLVS 226 K D +V D F F + P L G D++ +YS +K N V + Sbjct: 211 -KGTDTKIVHD--FAYGAFGFDAKNPSILASENGKDVAIEIYSLSKGYNMSGFRVG--FA 265 Query: 227 VNCESLHNRLRFLQNSLGAVP 247 V + + L+ Q A Sbjct: 266 VGNKDMIQALKKYQTHTNAGM 286 >2X8U-A nrPDB Length = 412 Score = 40.7 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 48/130 (36%), Gaps = 6/130 (4%) Query: 61 SRSGNPT---RNCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIICMDDVYGG 116 SR N T E A+ G ++ + F++G A I+ L GD II D + Sbjct: 81 SRVLNGTYQGHKACEDALKEFYGTEHAIVFSTGYQANLGMISTLAGKGDYIILDADSHAS 140 Query: 117 TNRYFRQVASEFGLKISFVDCSKIKL-LEAAITPETKLVWIETPTNPTQKVIDIEGCAHI 175 +E ++ + L KLV +E + + ++ + Sbjct: 141 IYDGCWLGDAEI-VRFRHNSVEDLDKRLGRLPAEAGKLVVLEGVYSMMGDIAPLQEMVAV 199 Query: 176 VHKHGDIILV 185 KHG +ILV Sbjct: 200 SKKHGAMILV 209 >3DZZ-A nrPDB Length = 391 Score = 40.3 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 46/116 (39%), Gaps = 17/116 (14%) Query: 86 AFASGL--AATVTITHLLKAGDQIICMDDVY--------GGTNRYFRQVASEFGLKISFV 135 FASG+ A + + GDQI+ + VY G R K S V Sbjct: 89 VFASGVVPAISAMVRQFTSPGDQILVQEPVYNMFYSVIEGNGRRVISSDLIYENSKYS-V 147 Query: 136 DCSKIKLLEAAITPETKLVWIETPTNPTQ---KVIDIEGCAHIVHKHGDIILVVDN 188 + + ++ E TP +++ P NP +++ A + KH ++L+ D Sbjct: 148 NWADLE--EKLATPSVRMMVFCNPHNPIGYAWSEEEVKRIAELCAKH-QVLLISDE 200 >3FFH-A nrPDB Length = 363 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 41/89 (46%), Gaps = 6/89 (6%) Query: 116 GTNRYFRQVASEFGLKISFV----DCS-KIKLLEAAITPETKLVWIETPTNPTQKVIDIE 170 T +RQ A G ++ + D ++ + AI +T +VWI P NPT I++ Sbjct: 116 PTFVQYRQNALIEGAEVREIPLLQDGEHDLEGMLNAIDEKTTIVWICNPNNPTGNYIELA 175 Query: 171 GC-AHIVHKHGDIILVVDNTFMSPYFQRP 198 A + D+++V+D ++ +P Sbjct: 176 DIQAFLDRVPSDVLVVLDEAYIEYVTPQP 204 >4J8L-A nrPDB Length = 361 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 38/181 (20%), Positives = 61/181 (33%), Gaps = 17/181 (9%) Query: 85 LAFASGLAAT-VTITHLLKAGDQ-IICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKL 142 L +G A + LLK G + ++ VY T Q GL + VD + + Sbjct: 70 LVQGAGTGAIRAGLAALLKPGQRLLVHDAPVYPTTRVIIEQ----MGLTLITVDFNDLSA 125 Query: 143 LEAAITPET--KLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLA 200 L+ + + + T P + + + G L DN + + Sbjct: 126 LKQVVDEQQPDAALVQHTRQQPQDSYV-LADVLATLRAAGVPALTDDNYAVMKVARIGCE 184 Query: 201 LGADISMYSATKYMN--GHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRG 258 GA++S +S K G VV + NR+R S G+ RG Sbjct: 185 CGANVSTFSCFKLFGPEGVGAVVG------DADVINRIRATLYSGGSQIQGAQALEVLRG 238 Query: 259 L 259 L Sbjct: 239 L 239 >4M2J-A nrPDB Length = 406 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 44/249 (17%), Positives = 83/249 (33%), Gaps = 29/249 (11%) Query: 61 SRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVY------ 114 S+ G R + A D + + S A +T+ LL GD+++ + +Y Sbjct: 83 SQGGEGVRRAIADRYAGGDADRVLVTHGSSEAIALTLNALLHRGDRVVVQEGIYHSLGHY 142 Query: 115 ----GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIE 170 G V ++ +D + L +TP T V + P NPT + + Sbjct: 143 PRAAGCDVA----VLPGRAVRDGEIDPDVLAGL---VTPGTAAVIVNFPHNPTGVTLSPQ 195 Query: 171 GCAHIVHKHGD--IILVVDNTFMS-----PYFQRPLALGADISMYSATKYMNGHSDVVMG 223 G + + +LV D P A G D Y G + +G Sbjct: 196 GLRALKERTAATGAVLVWDAATAEIAHRWEVLADPGADGGDTVSYGTLSKTFGLPGLRVG 255 Query: 224 LVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGL----KTLHVRMEKHFKNGMAVAQF 279 E L L++ SP+ + R + + + R + N + + Sbjct: 256 WAVAPKELLTATFP-LRDRTTLFLSPLVELVAERAVRHADELIGARAAEARHNLAHLTGW 314 Query: 280 LESNPWVEK 288 + ++ + + Sbjct: 315 MAAHEELVR 323 >4P3M-A nrPDB Length = 429 Score = 39.9 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 44/230 (19%), Positives = 76/230 (33%), Gaps = 37/230 (16%) Query: 42 SLSTTFKQGAPGQH--SGFEYSRSGNPTRNCLE----KAVAALDGAKYCLAFA-SGLAAT 94 L+ + +G PG+ G EY + E + +L GA Y SG A Sbjct: 50 QLTNKYAEGYPGKRYYGGCEY-------VDVAESLAIERAKSLFGADYANVQPHSGSQAN 102 Query: 95 VTI-THLLKAGDQIICMDDVYGGTNRYFRQV--------ASEFGL--KISFVDCSKIKLL 143 + L GD I+ M +GG + V A ++G+ + +D ++I+ L Sbjct: 103 AAVYQALCAPGDTILGMSLAHGGHLTHGSHVSFSGKMYNAVQYGITPETGILDYAEIERL 162 Query: 144 EAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV----VDNTFMSPYFQRPL 199 P + + ++D I K G + V V + + P+ Sbjct: 163 AVEHKPTMIIAGFSAYS----GIVDWAKFREIADKVGAYLFVDMAHVAGLVAAGLYPNPV 218 Query: 200 ALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSP 249 AD+ + K + G GL+ + G P Sbjct: 219 PF-ADVVTTTTHKTLGGPR---GGLILAKANEAIEKKLNSAVFPGQQGGP 264 >2FNU-A nrPDB Length = 375 Score = 39.5 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 35/185 (18%), Positives = 63/185 (34%), Gaps = 24/185 (12%) Query: 71 LEKAVAALDGAKYCLAFASGLAATVTIT----HLLKAGDQIICMDDVYGGTNRYFRQVAS 126 E+A+ G K+ L F S +A +T+ ++II + T Sbjct: 37 FEEALCEFLGVKHALVFNSATSALLTLYRNFSEFSADRNEIITTPISFVATANM----LL 92 Query: 127 EFGLKISFVDCS-----KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 E G F LE I TK + + K +++E + KH Sbjct: 93 ESGYTPVFAGIKNDGNIDELALEKLINERTKAI---VSVDYAGKSVEVESVQKLCKKHSL 149 Query: 182 IILVVDNTFMSPYFQRPLALG----ADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLR 237 L D++ + +G A + + A K + + G V N LH +++ Sbjct: 150 SFL-SDSSHALGSEYQNKKVGGFALASVFSFHAIKPI---TTAEGGAVVTNDSELHEKMK 205 Query: 238 FLQNS 242 ++ Sbjct: 206 LFRSH 210 >1B9H-A nrPDB Length = 388 Score = 38.7 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 41/196 (20%), Positives = 70/196 (35%), Gaps = 24/196 (12%) Query: 62 RSGNPTRNCLEKAVAALDGAKYCLAFASG-LAATVTITHL-LKAGDQIICMDDVYGGTNR 119 R G N E+ AA GA + LA +G A + + + + G ++I T Sbjct: 34 RMGGDEVNSFEREFAAHHGAAHALAVTNGTHALELALQVMGVGPGTEVIVP----AFTFI 89 Query: 120 YFRQVASEFGLKISFVDCS------KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCA 173 Q A G VD + + AA+TP TK++ P + + D++ A Sbjct: 90 SSSQAAQRLGAVTVPVDVDAATYNLDPEAVAAAVTPRTKVIM---PVHMAGLMADMDALA 146 Query: 174 HIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVV----MGLVSVNC 229 I G + L+ D + +G + S + + ++ G V Sbjct: 147 KISADTG-VPLLQDAAHAHGARWQGKRVG---ELDSIATFSFQNGKLMTAGEGGAVVFPD 202 Query: 230 ESLHN-RLRFLQNSLG 244 FL++S G Sbjct: 203 GETEKYETAFLRHSCG 218 >4R2N-A nrPDB Length = 367 Score = 38.4 bits (88), Expect = 0.005, Method: Composition-based stats. Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 31/167 (18%) Query: 81 AKYCLAFASGLAATV--TITHLLKAGDQIICMDD---VYGGTNRYFRQVASEFGLKISFV 135 A +A G + + GD+++ +Y R VA +++ Sbjct: 76 APEHVAVGCGSVSLCQQLVQVTASVGDEVVFGWRSFELYPPQVR----VAGAIPIQVPLT 131 Query: 136 D-CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV-VDNTFMSP 193 D + + A +T T+L+++ P NPT V+ + A V IL+ +D ++ Sbjct: 132 DHTFDLYAMLATVTDRTRLIFVCNPNNPTSTVVGPDALARFVEAVPAHILIAIDEAYVE- 190 Query: 194 YF---QRPLALG---AD---ISMYSATK----------YMNGHSDVV 221 Y RP +LG A + + + +K Y GH DV+ Sbjct: 191 YIRDGMRPDSLGLVRAHNNVVVLRTFSKAYGLAGLRIGYAIGHPDVI 237 >1IJI-A nrPDB Length = 356 Score = 37.2 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 39/106 (36%), Gaps = 18/106 (16%) Query: 95 VTITHLLKAG-DQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAIT----- 148 + I + G D I+ YG + A G++ V + + + Sbjct: 90 LLIRAFCEPGKDAILYCPPTYG----MYSVSAETIGVECRTVPT--LDNWQLDLQGISDK 143 Query: 149 -PETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTF 190 K+V++ +P NPT ++I D + G I+V D + Sbjct: 144 LDGVKVVYVCSPNNPTGQLINPQDFRTLLELTR--GKAIVVADEAY 187 >4LNJ-A nrPDB Length = 333 Score = 36.8 bits (84), Expect = 0.015, Method: Composition-based stats. Identities = 42/242 (17%), Positives = 77/242 (31%), Gaps = 33/242 (13%) Query: 65 NPTRNCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIICMDDVY------GGT 117 +PT N L+ A L G + + +G A V + + G++ I + GG Sbjct: 33 DPTVNALQDYAAELSGKEAAIFLPTGTQANLVALLSHCERGEEYIVGQAAHNYLFEAGGA 92 Query: 118 NRYFRQVASEFGLKISFVDCSKIKLLEAAITP------ETKLVWIETPTNPTQKVIDIEG 171 + + + + I P TKL+ +E N KV+ E Sbjct: 93 AVLGS--IQPQPIDAAADGTLPLDKVAMKIKPDDIHFARTKLLSLENTHN--GKVLPREY 148 Query: 172 CAHIVH--KHGDIILVVDN------TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMG 223 + ++ L VD + + D +K G V Sbjct: 149 LKEAWEFTRKRNLALHVDGARIFNAVVAYGCELKEITQYCDSFTICLSK---GLGTPVGS 205 Query: 224 LVSVNCESLHNRLRFLQNSLGAVPSPIDCYLCNRGLKTL---HVRMEKHFKNGMAVAQFL 280 L+ N + + +R+ + G L G+ L R+++ N +A+ L Sbjct: 206 LLVGNRDYIKRAIRW-RKMTGGGMR-QSGILAAAGMYALKNNVARLQEDHDNTAWMAEQL 263 Query: 281 ES 282 Sbjct: 264 RE 265 >6F77-B nrPDB Length = 400 Score = 36.8 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 25/127 (19%), Positives = 48/127 (37%), Gaps = 32/127 (25%) Query: 96 TITHLLKAGDQIICMDD----------VYGGTNRYF-RQVASEFGLKISFVDCSKIKLLE 144 L GD+++ + GGT + + + F LK + L+ Sbjct: 107 AFMATLNPGDEVVIPAPYWVSYPEMVALCGGTPVFVPTRQENNFKLKA--------EDLD 158 Query: 145 AAITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNT----------FM 191 AITP+TK +P+NP+ +++ ++ KH + ++ D+ F Sbjct: 159 RAITPKTKWFVFNSPSNPSGAAYSHEELKALTDVLMKHPHVWVLTDDMYEHLTYGDFRFA 218 Query: 192 SPYFQRP 198 +P P Sbjct: 219 TPVEVEP 225 >4FL0-A nrPDB Length = 456 Score = 36.4 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 53/130 (40%), Gaps = 11/130 (8%) Query: 115 GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAH 174 G T + + + + + A+TP T +++ +P NPT V + Sbjct: 177 GQTGHFHEKTKKYQNVVYMPCGPNNSFFPDLAMTPRTDVIFFCSPNNPTGYVASRKQLHQ 236 Query: 175 IV--HKHGDIILVVDNTFM------SP--YFQRPLALGADISMYSATKYMNGHSDVVMGL 224 +V K I++ D+ + SP ++ P A I + S +K+ G + V +G Sbjct: 237 LVDFAKTNGSIIIFDSAYAAFIEDGSPRSIYEIPGAREVAIEVSSFSKF-AGFTGVRLGW 295 Query: 225 VSVNCESLHN 234 + E L++ Sbjct: 296 SIIPDELLYS 305 >3IF2-A nrPDB Length = 444 Score = 36.4 bits (83), Expect = 0.025, Method: Composition-based stats. Identities = 20/62 (32%), Positives = 29/62 (46%), Gaps = 2/62 (3%) Query: 135 VDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH--KHGDIILVVDNTFMS 192 VD ++ L A + PTNPT V+ E AH+ K DI L++DN + Sbjct: 191 VDFEALENLPALKEGRIGAICCSRPTNPTGNVLTDEEMAHLAEIAKRYDIPLIIDNAYGM 250 Query: 193 PY 194 P+ Sbjct: 251 PF 252 >3G7Q-A nrPDB Length = 417 Score = 36.0 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 17/52 (32%), Positives = 29/52 (55%), Gaps = 4/52 (7%) Query: 146 AITPETKLVWIETPTNPTQKVI---DIEGCAHIVHKHGDIILVVDNTFMSPY 194 I ET ++ + PTNPT VI ++ + ++H +I LV+DN + P+ Sbjct: 176 HIGEETGMICVSRPTNPTGNVITDEELMKLDRLANQH-NIPLVIDNAYGVPF 226 >4CVQ-A nrPDB Length = 431 Score = 36.0 bits (82), Expect = 0.026, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 4/55 (7%) Query: 139 KIKLLEAAITPETKLVWIETPTNPTQKVIDIE---GCAHIVHKHGDIILVVDNTF 190 + + A ITP T+ + I P NPT V E I +H ++I+ D + Sbjct: 183 DLDDIRAKITPRTRGIVIINPNNPTGAVYSKELLMEIVEIARQH-NLIIFADEIY 236 >5WGB-A nrPDB Length = 426 Score = 36.0 bits (82), Expect = 0.027, Method: Composition-based stats. Identities = 34/188 (18%), Positives = 57/188 (30%), Gaps = 24/188 (12%) Query: 10 GFLPHFQHFATQA------IHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRS 63 G +P H + + A++P L + H+ Y Sbjct: 13 GLVPRGSHMLEMLRPLYMDVQATTPLDPRVLDAMLP--YLINYYGNPHSRTHA---YGWE 67 Query: 64 GNPTRNCLEKAVAALDGA-KYCLAFASGLA-----ATVTITHLLKA-GDQIICMDDVYGG 116 + VA+L GA + F SG A + ++ +I + Sbjct: 68 SEAAMERARQQVASLIGADPREIIFTSGATESNNIAIKGVARFYRSRKKHLITTQTEHKC 127 Query: 117 TNRYFRQVASEFGLKISFVDCS-----KIKLLEAAITPETKLVWIETPTNPTQKVIDIEG 171 R G +++++ +K LEAAI P+T LV + T N I Sbjct: 128 VLDSCR-SLEAEGFQVTYLPVQKSGIIDLKELEAAIQPDTSLVSVMTVNNEIGVKQPIAE 186 Query: 172 CAHIVHKH 179 I Sbjct: 187 IGRICSSR 194 >3MAF-B nrPDB Length = 518 Score = 36.0 bits (82), Expect = 0.031, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 27/68 (39%), Gaps = 5/68 (7%) Query: 118 NRYFRQVASEFGLKISFVDCS-----KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGC 172 + F + A FG+K+ + + AITP T +V P P V I Sbjct: 206 HAAFDKAAQYFGIKLVRTPLDADYRADVAAMREAITPNTVVVAGSAPGYPHGVVDPIPEI 265 Query: 173 AHIVHKHG 180 A + +HG Sbjct: 266 AALAAEHG 273 >5DJ3-A nrPDB Length = 376 Score = 35.7 bits (81), Expect = 0.035, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 46/117 (39%), Gaps = 10/117 (8%) Query: 79 DGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV--D 136 + + ++S ++ + L + D++ + T + GL + V D Sbjct: 80 EPGRVLSCYSSSVSMEILARSLSASVDRVALVH----PTFDNIADLLRGNGLDLVPVEED 135 Query: 137 CSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVH---KHGDIILVVDNTF 190 L A + V++ TP NPT +V+ E + +HG +L +D +F Sbjct: 136 ALHGADLSAELLSSVGCVFVTTPNNPTGRVLAEERLRRLAEQCAEHG-TVLALDTSF 191 >3HDO-A nrPDB Length = 360 Score = 34.9 bits (79), Expect = 0.064, Method: Composition-based stats. Identities = 36/214 (16%), Positives = 72/214 (33%), Gaps = 33/214 (15%) Query: 1 MQEKDASSQGFLPHFQHFATQA---IHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSG 57 +++ AS +G++P +Q + ++ ++P + V + ++ P + Sbjct: 6 LRQNIASMKGYIPGYQPPDIASWIKLNTNENPYPPSPEVVKAIL------EELGPDGAAL 59 Query: 58 FEYSRSGNPTRNCLEKAVAALDGAKYCL-------AFASGLAATVTITHLLKAGDQI--I 108 Y P+ + + + + G Y A S I G++I + Sbjct: 60 RIY-----PSASS--QKLREVAGELYGFDPSWIIMANGSDEVLNNLIRAFAAEGEEIGYV 112 Query: 109 CMDDVYGGTNRYFRQVASE-FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVI 167 Y GT + FGL F + E K+ ++ TP P Sbjct: 113 HPSYSYYGTLAEVQGARVRTFGLTGDFRIAGFPERYEG------KVFFLTTPNAPLGPSF 166 Query: 168 DIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLAL 201 +E + + + LV+D T+ L L Sbjct: 167 PLEYIDELARRCAGM-LVLDETYAEFAESNALEL 199 >1D2F-A nrPDB Length = 390 Score = 34.5 bits (78), Expect = 0.076, Method: Composition-based stats. Identities = 36/149 (24%), Positives = 61/149 (40%), Gaps = 24/149 (16%) Query: 55 HSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFAS-----GLAATVTITHLLKA----GD 105 H F YSR N + A+A ++ A S G + ++ L++ G+ Sbjct: 56 HGVFGYSRWKN---DEFLAAIAHWFSTQHYTAIDSQTVVYGPSVIYMVSELIRQWSETGE 112 Query: 106 QIICMDDVY-------GGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLVWIET 158 ++ Y G R VA E F D K++ + A PE K++ + + Sbjct: 113 GVVIHTPAYDAFYKAIEGNQRTVMPVALEKQADGWFCDMGKLEAVLA--KPECKIMLLCS 170 Query: 159 PTNPTQKV---IDIEGCAHIVHKHGDIIL 184 P NPT KV ++E A + +HG ++ Sbjct: 171 PQNPTGKVWTCDELEIMADLCERHGVRVI 199 >1LC8-A nrPDB Length = 364 Score = 34.5 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 36/213 (16%), Positives = 67/213 (31%), Gaps = 56/213 (26%) Query: 141 KLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGDIILVVDNTFMS----- 192 + A+TP+ +++ TP NPT + + ++ A +I L++D F+ Sbjct: 137 DAILEALTPDLDCLFLCTPNNPTGLLPERPLLQAIADRCKSL-NINLILDEAFIDFIPHE 195 Query: 193 ----PYFQ-RPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHN--------RLRFL 239 P + P + S TK+ + LV+ + ++ + L Sbjct: 196 TGFIPALKDNPHIW----VLRSLTKFYAIPGLRLGYLVNSDDAAMARMRRQQMPWSVNAL 251 Query: 240 QNSLGAVPSPIDCY------------------LCNRGLKT--------LHVRMEKHFKNG 273 G V + LC L T L +R E+ + Sbjct: 252 AALAGEVALQDSAWQQATWHWLREEGARFYQALCQLPLLTVYPGRANYLLLRCEREDIDL 311 Query: 274 MAVAQFLESNPWVE-KVIYPGLPSHPQHELVKR 305 + L + YPGL + + R Sbjct: 312 QR--RLLTQRILIRSCANYPGL-DSRYYRVAIR 341 >3G8M-A nrPDB Length = 417 Score = 34.5 bits (78), Expect = 0.095, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 63/181 (34%), Gaps = 32/181 (17%) Query: 42 SLSTTFKQGAPGQH--SGFEYSRSGNPTRNCLEK----AVAALDGAKYCLAFA-SGLAAT 94 L+ F +G PG+ G EY + +E+ L GA Y SG A Sbjct: 50 QLTNKFAEGYPGKRYYGGCEY-------VDIVEQLAIDRAKELFGADYANVQPHSGSQAN 102 Query: 95 VTI-THLLKAGDQIICMDDVYGGTNRYFRQV--------ASEFGLKIS-FVDCSKIKLLE 144 + T LL+ GD ++ M+ +GG + V +G+ + +D + ++ Sbjct: 103 FAVYTALLEPGDTVLGMNLAHGGHLTHGSPVNFSGKLYNIVPYGIDATGHIDYADLEKQA 162 Query: 145 AAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV----VDNTFMSPYFQRPLA 200 P+ + + V+D I G + V V + + P+ Sbjct: 163 KEHKPKMIIGGFSAYS----GVVDWAKMREIADSIGAYLFVDMAHVAGLVAAGVYPNPVP 218 Query: 201 L 201 Sbjct: 219 H 219 >2YRI-A nrPDB Length = 353 Score = 34.1 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 24/148 (16%), Positives = 44/148 (29%), Gaps = 19/148 (12%) Query: 70 CLEKAVAAL----DGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFR--Q 123 +++ +AAL +GA SG L G ++ ++ + Sbjct: 37 AIQERLAALFDPGEGALVAALAGSGSLGMEAGLANLDRGPVLVLVNGAFSQRVAEMAALH 96 Query: 124 VASEFGLKISFVDCSKIKLLEAAITPE----TKLVWIETPT---NPTQKVIDIEGCAHIV 176 L + + + A+ LV ET T NP E + Sbjct: 97 GLDPEVLDFPPGEPVDPEAVARALKRRRYRMVALVHGETSTGVLNPA------EAIGALA 150 Query: 177 HKHGDIILVVDNTFMSPYFQRPLALGAD 204 + G + + T + A+G D Sbjct: 151 KEAGALFFLDAVTTLGMLPFSMRAMGVD 178 >6C9E-A nrPDB Length = 422 Score = 33.7 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 21/47 (44%) Query: 139 KIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 ++ E + TK+V I +N + ++ + H+ G +L+ Sbjct: 169 ILEEFERKLNENTKMVAINYASNSLGTINPVKTMIKMAHEVGAKVLL 215 >3CQ5-A nrPDB Length = 369 Score = 33.3 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 37/104 (35%), Gaps = 13/104 (12%) Query: 96 TITHLLKAGDQIICMDDVYG-------GTNRYFRQVASEFGLKISFVDCSKIKLLEAAIT 148 + G + Y GT+ F +A G +D A Sbjct: 108 LLQAFGGPGRTALGFQPSYSMHPILAKGTHTEF--IAVSRGADFR-IDMDVALEEIRAKQ 164 Query: 149 PETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFMS 192 P+ +V++ TP NPT V ++ I++ I+ +VD + Sbjct: 165 PD--IVFVTTPNNPTGDVTSLDDVERIINVAPGIV-IVDEAYAE 205 >3A2B-A nrPDB Length = 398 Score = 33.0 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 23/136 (16%), Positives = 54/136 (39%), Gaps = 14/136 (10%) Query: 61 SRSGNPTRNC---LEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQIICMDD---- 112 SR N T + LE+ ++A G + + F++G + ++ L+ D I+ + Sbjct: 80 SRFLNGTLDIHVELEEKLSAYVGKEAAILFSTGFQSNLGPLSCLMGRNDYILLDERDHAS 139 Query: 113 VYGGTNRYFRQVASEFGLKISFVDCSKI-KLLEAAITPETKLVWIETPTNPTQKVIDIEG 171 + G+ F +V +K + + L KL+ + + ++++ Sbjct: 140 IIDGSRLSFSKV-----IKYGHNNMEDLRAKLSRLPEDSAKLICTDGIFSMEGDIVNLPE 194 Query: 172 CAHIVHKHGDIILVVD 187 I ++ ++V D Sbjct: 195 LTSIANEFDAAVMVDD 210 >4WBT-A nrPDB Length = 376 Score = 33.0 bits (74), Expect = 0.26, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 56/139 (40%), Gaps = 11/139 (7%) Query: 62 RSGNPTRNCLEKAVAA-LDGAKYCLAFASGLAATV--TITHLLKAGDQIICMDDVYGGTN 118 + +P + L++A+A L + +A G+ + + +++AG ++ Y T Sbjct: 67 KYADPENHDLKQALARHLGTSPANIAIGEGIDGLLGQIVRLVVEAGAPVVTSLGGY-PTF 125 Query: 119 RYFRQVASEFG--LKISFVD-CSKIKLLEAAI-TPETKLVWIETPTNPTQKVIDIEGCAH 174 Y VA G + + + D ++ L AA+ LV++ P NP E Sbjct: 126 NY--HVAGHGGRLVTVPYADDREDLEGLLAAVGRENAPLVYLANPDNPMGSWWPAERVVA 183 Query: 175 IVHKHGD-IILVVDNTFMS 192 + +LV+D + Sbjct: 184 FAQALPETTLLVLDEAYCE 202 >1DJ9-A nrPDB Length = 384 Score = 32.6 bits (73), Expect = 0.30, Method: Composition-based stats. Identities = 22/120 (18%), Positives = 44/120 (36%) Query: 68 RNCLEKAVAALDGAKYCLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASE 127 LE+ +A G L F SG AA + + A + I D + + ++ Sbjct: 86 HQALEEELAEWLGYSRALLFISGFAANQAVIAAMMAKEDRIAADRLSHASLLEAASLSPS 145 Query: 128 FGLKISFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVD 187 + + D + + L A+ P ++V E + + + +H ++V D Sbjct: 146 QLRRFAHNDVTHLARLLASPCPGQQMVVTEGVFSMDGDSAPLAEIQQVTQQHNGWLMVDD 205 >3QGU-A nrPDB Length = 449 Score = 32.2 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 26/75 (34%), Gaps = 9/75 (12%) Query: 129 GLKISFVDCSK--IKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHI---VHKHGDII 183 G++ + L A T +++ +P NPT + K+G I Sbjct: 188 GIEYMVCNPDNHFFPDLSKA--KRTDIIFFCSPNNPTGAAATRAQLTELVNFARKNGS-I 244 Query: 184 LVVDNTFMSPYFQRP 198 LV D + Y P Sbjct: 245 LVYDAAYA-LYISNP 258 >3GBX-A nrPDB Length = 420 Score = 32.2 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 62/181 (34%), Gaps = 32/181 (17%) Query: 42 SLSTTFKQGAPGQH--SGFEYSRSGNPTRNCLEK----AVAALDGAKYCLAFA-SGLAAT 94 L+ + +G PG+ G EY + +E+ L GA Y SG A Sbjct: 53 QLTNKYAEGYPGKRYYGGCEY-------VDVVEQLAIDRAKELFGADYANVQPHSGSQAN 105 Query: 95 VTI-THLLKAGDQIICMDDVYGGTNRYFRQV--------ASEFGL-KISFVDCSKIKLLE 144 + T LL+ GD ++ M+ GG + V +G+ + +D ++ L Sbjct: 106 FAVYTALLQPGDTVLGMNLAQGGHLTHGSPVNFSGKLYNIVPYGIDESGKIDYDEMAKLA 165 Query: 145 AAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV----VDNTFMSPYFQRPLA 200 P+ + + V+D I G + V V + + P+ Sbjct: 166 KEHKPKMIIGGFSAYS----GVVDWAKMREIADSIGAYLFVDMAHVAGLIAAGVYPNPVP 221 Query: 201 L 201 Sbjct: 222 H 222 >6ONN-A nrPDB Length = 402 Score = 31.8 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 43/126 (34%), Gaps = 8/126 (6%) Query: 68 RNCLEKAVAALDGA----KYCLAFASG-LAATVTITHLLKAGDQIICMDDVYGGTNRYFR 122 LE +A G L F++G +A T+T L G + D + Sbjct: 94 HAQLEDDLAEFAGGFVDNPRALYFSTGYMANLATLTALAGRGTTLFS--DSLNHASLIDG 151 Query: 123 QVASEFGLKI-SFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGD 181 S ++I D + + A KL+ +T + + + + HG Sbjct: 152 ARLSRADIQIYPHADAEALGAMLEASDAAVKLIVSDTVFSMDGDIAPLARLLELAEHHGA 211 Query: 182 IILVVD 187 ++V D Sbjct: 212 WLVVDD 217 >3ELE-A nrPDB Length = 398 Score = 31.8 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 37/229 (16%), Positives = 70/229 (30%), Gaps = 46/229 (20%) Query: 139 KIKLLEAAITPETKLVWIETPTNPTQKVID---IEGCAHIVHKHGD-----IILVVDN-- 188 LE I T+ V I +P NP+ V I+ + ++ K I ++ D Sbjct: 161 DFDALEERINAHTRGVIINSPNNPSGTVYSEETIKKLSDLLEKKSKEIGRPIFIIADEPY 220 Query: 189 ----------TFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRF 238 F++ Y+ L YS +K ++ + + ++ + L Sbjct: 221 REIVYDGIKVPFVTKYYDNTL------VCYSYSKSLSLPGERIGYVLVPDEVYDKAELYA 274 Query: 239 LQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESNPWVEKVIYPGLPSHP 298 G Y+C L +K + + ++Y GL + Sbjct: 275 AVCGAGRALG----YVCAPSL------FQKMIVKCQGATGDINAYKENRDLLYEGL-TRI 323 Query: 299 QHELVKRQCTGCTGMVTFYIKGTLQHAEIFLKNLK----LFTLAESLGG 343 + K G ++K + F + K L A+ G Sbjct: 324 GYHCFK-----PDGAFYMFVKALEDDSNAFCEKAKEEDVLIVAADGFGC 367 >3EZS-A nrPDB Length = 376 Score = 31.8 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 35/219 (15%), Positives = 70/219 (31%), Gaps = 37/219 (16%) Query: 41 ISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFASGLAATVTITHL 100 I + F++ GF R + + ++ L + F S + Sbjct: 54 IYPKSAFEESLRAAQRGFFKRRFKIELKEN--ELISTLGSREVLFNFPS-----FVLFDY 106 Query: 101 LKAGDQIICMDD---VYGGTNRYFR--QVASEFGLKISFVDCSKIKLLEAAITPETKLVW 155 I + +Y G ++ + + + F K L+ E LV Sbjct: 107 QNP--TIAYPNPFYQIYEGAAKFIKAKSLLMPLTKENDFTPSLNEKELQ-----EVDLVI 159 Query: 156 IETPTNPTQKVIDIEGC---AHIVHKHGDIILVVDNTFMS-------PYFQRPLALGAD- 204 + +P NPT + + +E + KH D IL+ D + P L + Sbjct: 160 LNSPNNPTGRTLSLEELISWVKLALKH-DFILINDECYSEIYENTPPPSLLEACMLAGNE 218 Query: 205 -----ISMYSATKYMNGHSDVVMGLVSVNCESLHNRLRF 238 + ++S +K + + G ++ + L F Sbjct: 219 AFKNVLVIHSLSKRSSAPG-LRSGFIAGDSRLLEKYKAF 256 >5VNX-A nrPDB Length = 393 Score = 31.4 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 47/123 (38%), Gaps = 8/123 (6%) Query: 71 LEKAVAALDGA----KYCLAFASG-LAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVA 125 LE +A G L F++G +A +T L AG D + Sbjct: 89 LEDELAGFAGGFSDAPRALYFSTGYMANLAAVTAL--AGKDATIFSDALNHASLIDGTRL 146 Query: 126 SEFGLKI-SFVDCSKIKLLEAAITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIIL 184 S +++ D + + L A T +TKL+ +T + + + + +HG ++ Sbjct: 147 SRATVQVYPHADTATLGALLEACTSQTKLIVTDTVFSMDGDIAPLAELLALAERHGAWLV 206 Query: 185 VVD 187 V D Sbjct: 207 VDD 209 >3LWS-A nrPDB Length = 357 Score = 31.4 bits (70), Expect = 0.65, Method: Composition-based stats. Identities = 38/239 (15%), Positives = 81/239 (33%), Gaps = 31/239 (12%) Query: 69 NCLEKAVAALDGAKYCLAFASG-LAATVTITHLLKAGDQ-IICMDDVYGGTNRYFRQ--- 123 E+ A + G + F SG +A V + D + + + + Sbjct: 50 EPFEQKFADVLGMDDAVFFPSGTMAQQVALRIWSDETDNRTVAYHPL---CHLEIHEQDG 106 Query: 124 VASEFGLKISFVDCSK----IKLLEAAITPETKLVWIETPTNPTQKVI----DIEGCAHI 175 + ++ V + + ++A P+ + +E P V ++E + Sbjct: 107 LKELHPIETILVGAADRLMTLDEIKAL--PDIACLLLELPQREIGGVAPAFSELETISRY 164 Query: 176 VHKHGDIILVVDNTF---MSPYFQRPLALGA---DISMYSATKYMNGHSDVVMGLVSVNC 229 + G I L +D M PY+++ A A D S K + G + G + Sbjct: 165 CRERG-IRLHLDGARLFEMLPYYEKTAAEIAGLFDSIYISFYKGLGG----IAGAILAGP 219 Query: 230 ESLHNRLRFLQNSLGAVPSPIDCYLCNRG--LKTLHVRMEKHFKNGMAVAQFLESNPWV 286 + R + G + Y+ + + RM ++++ +A+ + P V Sbjct: 220 AAFCQTARIWKRRYGGDLISLYPYIVSADYYYELRKDRMGQYYEQAKQLAEQFNALPGV 278 Score = 29.5 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 20/46 (43%) Query: 206 SMYSATKYMNGHSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPID 251 S T ++GH +G++ ++ + + Q GA+ P + Sbjct: 8 SFQQTTGQISGHGKRNVGVLKTAFAAVADEMASDQYGTGAIIEPFE 53 >4LW2-A nrPDB Length = 404 Score = 31.4 bits (70), Expect = 0.67, Method: Composition-based stats. Identities = 21/100 (21%), Positives = 41/100 (41%), Gaps = 5/100 (5%) Query: 91 LAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCS-----KIKLLEA 145 + A L+ GD+II + + VA + G K+ + + + LL Sbjct: 99 MVAQCYARPRLQPGDEIIVSVAEHHANLVPWLMVAQQTGAKVVKLPLNAQRLPDVDLLPE 158 Query: 146 AITPETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 ITP ++++ + +N T D+ H G +++V Sbjct: 159 LITPRSRILALGQMSNVTGGCPDLARAITFAHSAGMVVMV 198 >6MRE-A nrPDB Length = 420 Score = 31.4 bits (70), Expect = 0.68, Method: Composition-based stats. Identities = 16/90 (17%), Positives = 37/90 (41%), Gaps = 5/90 (5%) Query: 101 LKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV-----DCSKIKLLEAAITPETKLVW 155 ++AGD II + ++ + + G ++ + +++ L +T+L+ Sbjct: 124 VRAGDNIIISQMEHHANIVPWQMLCARVGAELRVIPLNPDGTLQLETLPTLFDEKTRLLA 183 Query: 156 IETPTNPTQKVIDIEGCAHIVHKHGDIILV 185 I +N + + H+HG +LV Sbjct: 184 ITHVSNVLGTENPLAEMITLAHQHGAKVLV 213 >3JTX-A nrPDB Length = 396 Score = 31.0 bits (69), Expect = 0.86, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 27/55 (49%), Gaps = 2/55 (3%) Query: 150 ETKLVWIETPTNPTQKVIDIEGCAHI--VHKHGDIILVVDNTFMSPYFQRPLALG 202 TKLV++ +P NP+ V+D++G + + I+ D + YF LG Sbjct: 168 RTKLVFVCSPNNPSGSVLDLDGWKEVFDLQDKYGFIIASDECYSEIYFDGNKPLG 222 >2Z9W-A nrPDB Length = 392 Score = 30.7 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 29/171 (16%), Positives = 60/171 (35%), Gaps = 10/171 (5%) Query: 90 GLAATVTITHLLKAGDQII-CMDDVYGGTNRYFRQVASE--FGLKISFVDCSKIKLLEAA 146 GL A L+ D ++ VYG Y+ + S +++ + + + + Sbjct: 71 GLEAAAA--SLISPDDVVLNLASGVYGKGFGYWAKRYSPHLLEIEVPYNEAIDPQAVADM 128 Query: 147 IT--PETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILVVDNTFM-SPYFQRPLALGA 203 + PE +V + P+ + I+ +V HG L+VD P A Sbjct: 129 LKAHPEITVVSVCHHDTPSGTINPIDAIGALVSAHGA-YLIVDAVSSFGGMKTHPEDCKA 187 Query: 204 DISMYSATKYMNG-HSDVVMGLVSVNCESLHNRLRFLQNSLGAVPSPIDCY 253 DI + K + +MG+ + + S+ ++ + + Sbjct: 188 DIYVTGPNKCLGAPPGLTMMGVSERAWAKMKANPLAPRASMLSIVDWENAW 238 >4DUT-A nrPDB Length = 145 Score = 30.7 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 22/115 (19%), Positives = 39/115 (33%), Gaps = 15/115 (13%) Query: 52 PGQHSGFEYSRSGNPTRNCLEKAVAALDGAKYCLAFA------------SGLAATVTITH 99 G YSR N + +A L A +A + + + Sbjct: 20 AKNVIGQIYSRFENAGLKIVAARMAHLSRADAEKFYAVHAERPFFKDLVEFMISGPVMIQ 79 Query: 100 LLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLV 154 +L+ D I+ D+ G T+ + A + ++ F D + + PET V Sbjct: 80 VLEGEDAILKNRDLMGATD---PKKAEKGTIRADFADSIDANAVHGSDAPETARV 131 >1C7O-A nrPDB Length = 399 Score = 30.3 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 29/84 (34%), Gaps = 13/84 (15%) Query: 92 AATVTITHLLKAGDQIICMDDVYGGTNRYFR---------QVASEFGLKISFVDCSKIKL 142 A + K GD +I + VY + ++ + G +D K++ Sbjct: 101 AVFNAVREFTKPGDGVIIITPVYYPFFMAIKNQERKIIECELLEKDGYYT--IDFQKLEK 158 Query: 143 LEAAITPETKLVWIETPTNPTQKV 166 L K + +P NP +V Sbjct: 159 LSK--DKNNKALLFCSPHNPVGRV 180 >1T6J-A nrPDB Length = 716 Score = 29.9 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 30/84 (35%), Gaps = 4/84 (4%) Query: 222 MGLVSVNCESLHNRLRFL--QNSLGAVPSPIDCYLCNRGLK-TLHVRMEKHFKNGMAVAQ 278 G E + + L G +PS D + RGL+ +L + + + + V Sbjct: 117 GGSADTRTEDAISLQKALLEHQLCGVLPSSFDSFRLGRGLENSLPLEVVRGAMT-IRVNS 175 Query: 279 FLESNPWVEKVIYPGLPSHPQHEL 302 + V V+ L + H + Sbjct: 176 LTRGHSAVRLVVLEALTNFLNHGI 199 >5VMB-A nrPDB Length = 425 Score = 29.9 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 49/261 (18%), Positives = 95/261 (36%), Gaps = 36/261 (13%) Query: 43 LSTTFKQGAPGQHSGFEYSRSGNPTRNCLEK----AVAALDGAKYCLA--FASGLAATVT 96 L+ + +G PG+ Y G + +E+ L GA Y A A + Sbjct: 58 LTNKYAEGYPGKR---YYG--GCEFVDVIEQMAIDRAKELFGADYANVQPHAGSQANSAV 112 Query: 97 ITHLLKAGDQIICMDDVYGG--------TNRYFRQVASEFGLKISFVDCSKIKLLEAAIT 148 LL GD ++ M +GG + A ++GL + ++ A+ Sbjct: 113 YLALLNPGDTVLGMSLAHGGHLTHGAKVSFSGKTYNAVQYGLNAETGEIDYEEVERLALE 172 Query: 149 PETKLVWIETPTNPTQKVIDIEGCAHIVHKHGDIILV----VDNTFMSPYFQRPLALGAD 204 + +++ +V+D + I K G + V V + + P+ + AD Sbjct: 173 HKPRMIVAGFSA--YSRVVDWQRFRDIADKVGAYLFVDMAHVAGLVAAGVYPNPVQI-AD 229 Query: 205 ISMYSATKYMNGHSDVVMGLVSVNC-ESLHNRLR---FLQNSLGAVPSPIDC-YLCNRGL 259 ++ + K + G GL+ E + +L+ F N G + I +C + Sbjct: 230 VTTTTTHKTLRGPR---SGLILAKANEEIEKKLQSAVFPGNQGGPLMHAIAAKAICFKEA 286 Query: 260 KTLHVRMEKHF--KNGMAVAQ 278 + + + KN A+A+ Sbjct: 287 MSDDFKAYQQQVVKNAQAMAE 307 >3H14-A nrPDB Length = 391 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 24/130 (18%), Positives = 43/130 (33%), Gaps = 27/130 (20%) Query: 70 CLEKAVAALDGAKYCLAF----------ASGLAATVTITHLLKAGDQIICMDDVYGGTNR 119 L + +A L G Y + +SG + T L +GD++ Y Sbjct: 72 ALRQRIARLYGEWYGVDLDPGRVVITPGSSG-GFLLAFTALFDSGDRVGIGAPGYPS--- 127 Query: 120 YFRQVASEFGLKISFVDCSKIKLLEAAITP--------ETKLVWIETPTNPTQKVIDIEG 171 +RQ+ GL V E + P + + + +P NPT ++D Sbjct: 128 -YRQILRALGL----VPVDLPTAPENRLQPVPADFAGLDLAGLMVASPANPTGTMLDHAA 182 Query: 172 CAHIVHKHGD 181 ++ Sbjct: 183 MGALIEAAQA 192 >5XF9-A nrPDB Length = 591 Score = 29.5 bits (65), Expect = 2.5, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 19/41 (46%) Query: 171 GCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSAT 211 + +H+HG ++ +D T F+ P A D + + T Sbjct: 156 AVTNAIHRHGPLLTWLDTTPAEAVFEHPTAHDPDAILQAVT 196 >4GDY-A nrPDB Length = 439 Score = 29.5 bits (65), Expect = 2.9, Method: Composition-based stats. Identities = 14/80 (17%), Positives = 25/80 (31%), Gaps = 4/80 (5%) Query: 84 CLAFASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLL 143 C+ S ++ GD ++ + Y GT Q G I V + ++ Sbjct: 112 CVTSGSQQGLCKVFEMIINPGDNVLLDEPAYSGTL----QSLHPLGCNIINVASDESGIV 167 Query: 144 EAAITPETKLVWIETPTNPT 163 ++ E NP Sbjct: 168 PDSLRDILSRWKPEDAKNPQ 187 >3V7N-A nrPDB Length = 487 Score = 29.1 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 20/45 (44%), Gaps = 3/45 (6%) Query: 239 LQNSLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMAVAQFLESN 283 ++ +LG PS + GL+ L R E N V F+ ++ Sbjct: 443 IREALGQEPSRPAAF---DGLEALPQRFEVVDANAQQVKDFIAAH 484 >2YKV-A nrPDB Length = 465 Score = 29.1 bits (64), Expect = 3.9, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 22/65 (33%), Gaps = 3/65 (4%) Query: 10 GFLPHFQHFATQAIHVGQDPEQWTSRAVVPPISLSTTFKQGAPGQHSGFEYSRSGNP--- 66 G +P H G+ P T+ + TF + P E +R P Sbjct: 13 GLVPRGSHMNEPIGEPGRSPASDTAEKAQAIAAARNTFARDNPVSAGHHERARRSMPGGN 72 Query: 67 TRNCL 71 TR+ L Sbjct: 73 TRSIL 77 >4LIS-A nrPDB Length = 371 Score = 28.7 bits (63), Expect = 4.7, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 25/60 (41%), Gaps = 2/60 (3%) Query: 88 ASGLAATVTITHLLKAGDQIICMDDVYGGTNRYFRQVASEFGLKISFV--DCSKIKLLEA 145 +G + T LL+AG +++ D++Y + ++ G K F D + + Sbjct: 11 GTGYIGSFTTLALLEAGYKVVVADNLYNSSAEALNRIELISGKKAEFAQLDVTDEAAFDK 70 >3QYQ-A nrPDB Length = 293 Score = 28.7 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 12/25 (48%), Positives = 14/25 (56%) Query: 74 AVAALDGAKYCLAFASGLAATVTIT 98 AVAAL+G L +SGL AT Sbjct: 173 AVAALEGGADFLQTSSGLGATHATM 197 >4LHD-A nrPDB Length = 983 Score = 28.3 bits (62), Expect = 5.3, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 37/107 (34%), Gaps = 10/107 (9%) Query: 109 CMDDVYGGTNRYFRQVASEFGLKISFVDCSKIKLLEAAITPETKLV--WIETPTNPTQKV 166 D + T + A+ G+++ D + T + ++ P V Sbjct: 193 VAQDCHPQTIEVIKTRANPLGIEVIVGD-------HHTFSFSTSIFGALLQYPAT-DGAV 244 Query: 167 IDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISMYSATKY 213 D H+H ++ + + P LGADI++ S ++ Sbjct: 245 YDYRSFIDKAHQHQALVTLAADPLSLTLLTPPGELGADIAVGSTQRF 291 >4QAI-A nrPDB Length = 407 Score = 28.3 bits (62), Expect = 6.2, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 28/66 (42%), Gaps = 5/66 (7%) Query: 14 HFQHFATQAIHVGQDPEQWTSR-AVVPPISLSTTFKQGAPGQHSGFEYSRSGNPTRNCLE 72 + +TQ I +G+ + + + P+S S T++ A + + GNP R Sbjct: 104 NGSFVSTQLIFLGRVADPAVMKTRGLNPVSASATYESDAAKEAAEAV----GNPVRALTT 159 Query: 73 KAVAAL 78 + V L Sbjct: 160 QEVKDL 165 >4J5U-A nrPDB Length = 420 Score = 28.3 bits (62), Expect = 6.3, Method: Composition-based stats. Identities = 45/234 (19%), Positives = 77/234 (32%), Gaps = 32/234 (13%) Query: 73 KAVAALDGAKYCLAFA-SG-LAATVTITHLLKAGDQIICMDDVYGG----------TNRY 120 + V L KY SG A LL+ GD ++ M GG + ++ Sbjct: 80 ERVKKLFNCKYANVQPHSGSQANQAVYLALLQPGDTVLGMSLDSGGHLTHGAAPNMSGKW 139 Query: 121 FRQVASEFGLKISFVDCSKIKLLEAAITPETKLV-WIETPTNPTQKVIDIEGCAHIVHKH 179 F V+ + +D +I+ L P+ + + P N ID IV K Sbjct: 140 FNAVSYSVNKETYLIDYDEIERLADLHKPKLLIAGFSAYPRN-----IDFAKFREIVDKV 194 Query: 180 GDIILV----VDNTFMSPYFQRPLALGADISMYSATKYMNGHSDVVMGLVSVNCESLHNR 235 G + + + Q P+ A + K + G GL+ N E + ++ Sbjct: 195 GAYFMADIAHIAGLVATGEHQSPIPY-AHAVTSTTHKTLRGPR---GGLILSNDEEIGHK 250 Query: 236 L--RFLQNSLGAVPSPIDCYLCNRGLKTLHVR----MEKHFKNGMAVAQFLESN 283 + G I L+ L +++ N A+A L+ Sbjct: 251 INSALFPGLQGGPLMHIIAAKAVAFLENLQPEYKSYIQQVISNAKALASSLQER 304 >2ZAK-A nrPDB Length = 320 Score = 28.3 bits (62), Expect = 6.3, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 38/110 (34%), Gaps = 15/110 (13%) Query: 220 VVMGLVSVNCESLHNRLRFLQN----SLGAVPSPIDCYLCNRGLKTLHVRMEKHFKNGMA 275 V G+ + L RL Q+ +G + + RG++ + + F + Sbjct: 95 AVAGVSHLRNPVLAARLVMEQSPHVMMIGEGA---ENFAFARGMERVSPEI---FSTSLR 148 Query: 276 VAQFLESNPWVEKVIYPGLPSHPQHELVKRQCTGCTGMVTFYIKGTLQHA 325 Q L + V+ H L ++Q G G V + G L A Sbjct: 149 YEQLLAARKEGATVL-----DHSGAPLDEKQKMGAVGAVALDLDGNLAAA 193 >1WYT-A nrPDB Length = 438 Score = 28.3 bits (62), Expect = 6.6, Method: Composition-based stats. Identities = 12/47 (25%), Positives = 20/47 (42%) Query: 161 NPTQKVIDIEGCAHIVHKHGDIILVVDNTFMSPYFQRPLALGADISM 207 N + D+ A H G + + V + + P A GADI++ Sbjct: 206 NFLGALEDLGPFAEAAHGAGALFVAVADPLSLGVLKPPGAYGADIAV 252 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.149 0.431 Lambda K H 0.267 0.0454 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,586,812 Number of Sequences: 36641 Number of extensions: 752717 Number of successful extensions: 2509 Number of sequences better than 10.0: 135 Number of HSP's better than 10.0 without gapping: 106 Number of HSP's successfully gapped in prelim test: 88 Number of HSP's that attempted gapping in prelim test: 2175 Number of HSP's gapped (non-prelim): 208 length of query: 405 length of database: 10,336,785 effective HSP length: 99 effective length of query: 306 effective length of database: 6,709,326 effective search space: 2053053756 effective search space used: 2053053756 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)