BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P32861
         (499 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

2I5K-A nrPDB                                                         1002   0.0  
3R2W-A nrPDB                                                          514   e-146
5WEG-A nrPDB                                                          500   e-142
2Q4J-A nrPDB                                                          469   e-132
3GUE-A nrPDB                                                          309   2e-84
4M2B-A nrPDB                                                          273   1e-73
1VM8-A nrPDB                                                           49   4e-06
1JV1-A nrPDB                                                           47   3e-05
4BMA-A nrPDB                                                           44   2e-04
3OC9-A nrPDB                                                           40   0.003
2YQJ-A nrPDB                                                           36   0.044
1LFW-A nrPDB                                                           32   0.93 
2N5T-A nrPDB                                                           31   0.98 
4ZBK-B nrPDB                                                           31   1.6  
5JAA-A nrPDB                                                           30   3.4  

>2I5K-A nrPDB
          Length = 488

 Score = 1002 bits (2591), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 12  TYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTT 71
           TYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTT
Sbjct: 1   TYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTT 60

Query: 72  LEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREG 131
           LEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREG
Sbjct: 61  LEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREG 120

Query: 132 NTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPR 191
           NTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPR
Sbjct: 121 NTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPR 180

Query: 192 VYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT 251
           VYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT
Sbjct: 181 VYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT 240

Query: 252 VDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIR 311
           VDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIR
Sbjct: 241 VDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIR 300

Query: 312 KFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHF 371
           KFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHF
Sbjct: 301 KFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHF 360

Query: 372 DGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVS 431
           DGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVS
Sbjct: 361 DGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVS 420

Query: 432 GFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT 491
           GFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT
Sbjct: 421 GFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT 480

Query: 492 GNLQILEH 499
           GNLQILEH
Sbjct: 481 GNLQILEH 488


>3R2W-A nrPDB
          Length = 528

 Score =  514 bits (1323), Expect = e-146,   Method: Compositional matrix adjust.
 Identities = 264/474 (55%), Positives = 355/474 (74%), Gaps = 19/474 (4%)

Query: 40  LDDAARAKFEN---ELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQ-- 94
           L  A+  +FE+   +LD F  LF R+L EK    +++W KI+ P  D +  YE I  +  
Sbjct: 60  LTTASSHEFEHTKKDLDGFRKLFHRFLQEKGP--SVDWGKIQRPPEDSIQPYEKIKARGL 117

Query: 95  PENVSN-LSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDV 153
           P+N+S+ L+KL V+KLNGGLGTSMGC GPKS+I VR  NTFLDL+V+QIE+LN+ Y++DV
Sbjct: 118 PDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVRNENTFLDLTVQQIEHLNKTYNTDV 177

Query: 154 PLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSP---LDA 210
           PL+LMNSFNTD+DT+ +++KY+  R++I +FNQSR+PR+ K+SLLPV  +        +A
Sbjct: 178 PLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRYPRINKESLLPVAKDVSYSGENTEA 237

Query: 211 WYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIE----TGAE 266
           WYPPGHGD++ S + SG LD  I +G+E +FVSN DNLGATVDL ILNH++        E
Sbjct: 238 WYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNIDNLGATVDLYILNHLMNPPNGKRCE 297

Query: 267 YIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLK 326
           ++ME+T+KTRADVKGGTL  Y+G++RL+E+AQVPK H+DEFK++ KF  FNTNNLWI+L 
Sbjct: 298 FVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKAHVDEFKSVSKFKIFNTNNLWISLA 357

Query: 327 AVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFLP 386
           AVKRL E + ++MEII N KT+  DG  +NV+QLETA GAAI+ F+ + G+ VPRSRFLP
Sbjct: 358 AVKRLQEQNAIDMEIIVNAKTL--DGG-LNVIQLETAVGAAIKSFENSLGINVPRSRFLP 414

Query: 387 VKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPN-PLIKLGSHFKKVSGFNARIPHIPKIVE 445
           VKT SDLLLV S+L+ L  GSL +   R  P  PL+KLGS F KV  +  R   IP ++E
Sbjct: 415 VKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLVKLGSSFTKVQDYLRRFESIPDMLE 474

Query: 446 LDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTGNLQILEH 499
           LDHLT++G+V  GK+V+L+GTVII+ + G +IDIP G++LEN +V+GNL+IL+H
Sbjct: 475 LDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPPGAVLENKIVSGNLRILDH 528


>5WEG-A nrPDB
          Length = 476

 Score =  500 bits (1288), Expect = e-142,   Method: Compositional matrix adjust.
 Identities = 265/468 (56%), Positives = 342/468 (73%), Gaps = 16/468 (3%)

Query: 31  LNKL-ADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYE 89
           L+KL A+ +KLD  +    ENE   F +L  RYL  ++ +  +EW KI++P  + VV Y+
Sbjct: 15  LDKLRAEVAKLDQIS----ENEKAGFISLVSRYLSGEAEQ--IEWSKIQTPTDEVVVPYD 68

Query: 90  IISQQPENVSN----LSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYL 145
            ++  PE++      L KL VLKLNGGLGT+MGC GPKSVIEVR G TFLDL V QIE L
Sbjct: 69  TLASPPEDLEETKKLLDKLVVLKLNGGLGTTMGCTGPKSVIEVRNGFTFLDLIVIQIESL 128

Query: 146 NRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYD 205
           N++Y   VPLLLMNSFNT  DT+ +++KYS + I I +FNQS++PR+  +  LP+P++  
Sbjct: 129 NKKYGCSVPLLLMNSFNTHDDTQKIVEKYSNSNIEIHTFNQSQYPRIVTEDFLPLPSKGK 188

Query: 206 SPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGA 265
           S  D WYPPGHGD+F SL+ SG+LD L+AQG+E +F++N DNLGA VD+KILNH+I    
Sbjct: 189 SGKDGWYPPGHGDVFPSLNNSGKLDILLAQGKEYVFIANSDNLGAIVDIKILNHLINNQN 248

Query: 266 EYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINL 325
           EY ME+T KT ADVKGGTLISY+G+V+LLE+AQVP EH++EFK+I KF  FNTNNLW+NL
Sbjct: 249 EYCMEVTPKTLADVKGGTLISYEGRVQLLEIAQVPDEHVNEFKSIEKFKIFNTNNLWVNL 308

Query: 326 KAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFL 385
           KA+KRL+E+  L+MEIIPN K +  DG  + VLQLETA GAAIR FD A G+ VPRSRFL
Sbjct: 309 KAIKRLVEAEALKMEIIPNPKEV--DG--VKVLQLETAAGAAIRFFDKAIGINVPRSRFL 364

Query: 386 PVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGP-NPLIKLGSHFKKVSGFNARIPHIPKIV 444
           PVK  SDLLLV+SDL+ L  G +  +P+R  P NP I+LG  FKKV+ F AR   IP IV
Sbjct: 365 PVKATSDLLLVQSDLYTLVDGFVIRNPARANPANPSIELGPEFKKVANFLARFKSIPSIV 424

Query: 445 ELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTG 492
           ELD L ++G+V+ G  +TL+G V I    G K++IP+G++LEN  V G
Sbjct: 425 ELDSLKVSGDVWFGSGITLKGKVTITAKSGVKLEIPDGAVLENKDVNG 472


>2Q4J-A nrPDB
          Length = 469

 Score =  469 bits (1207), Expect = e-132,   Method: Compositional matrix adjust.
 Identities = 241/472 (51%), Positives = 327/472 (69%), Gaps = 21/472 (4%)

Query: 26  QMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEV 85
           Q+++A++ L + S          E+E   F +L  RYL  ++    +EW KI++P  + V
Sbjct: 10  QLKSAVDGLTEMS----------ESEKSGFISLVSRYLSGEAQH--IEWSKIQTPTDEIV 57

Query: 86  VKYEIISQQPENVSNLSKLAVLKL----NGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQ 141
           V YE ++   ++V+    L    +    NGGLGT+MGC GPKSVIEVR+G TFLDL V Q
Sbjct: 58  VPYEKMTPVSQDVAETKNLLDKLVVLKLNGGLGTTMGCTGPKSVIEVRDGLTFLDLIVIQ 117

Query: 142 IEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVP 201
           IE LN +Y   VPL+LMNSFNT  DT  +++KY+ + + I +FNQS++PRV  D  +P P
Sbjct: 118 IENLNNKYGCKVPLVLMNSFNTHDDTHKIVEKYTNSNVDIHTFNQSKYPRVVADEFVPWP 177

Query: 202 TEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMI 261
           ++  +  + WYPPGHGD+F +L  SG+LD  ++QG+E +FV+N DNLGA VDL IL H+I
Sbjct: 178 SKGKTDKEGWYPPGHGDVFPALMNSGKLDTFLSQGKEYVFVANSDNLGAIVDLTILKHLI 237

Query: 262 ETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNL 321
           +   EY ME+T KT ADVKGGTLISY+G+V+LLE+AQVP EH++EFK+I KF  FNTNNL
Sbjct: 238 QNKNEYCMEVTPKTLADVKGGTLISYEGKVQLLEIAQVPDEHVNEFKSIEKFKIFNTNNL 297

Query: 322 WINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPR 381
           W+NLKA+K+L+E+  L+MEIIPN K +  DG  + VLQLETA GAAIR FD A GV VPR
Sbjct: 298 WVNLKAIKKLVEADALKMEIIPNPKEV--DG--VKVLQLETAAGAAIRFFDNAIGVNVPR 353

Query: 382 SRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGP-NPLIKLGSHFKKVSGFNARIPHI 440
           SRFLPVK  SDLLLV+SDL+ L  G +  + +R  P NP I+LG  FKKV+ F +R   I
Sbjct: 354 SRFLPVKASSDLLLVQSDLYTLVDGFVTRNKARTNPSNPSIELGPEFKKVATFLSRFKSI 413

Query: 441 PKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTG 492
           P IVELD L ++G+V+ G  + L+G V +    G K++IP+ +++EN  + G
Sbjct: 414 PSIVELDSLKVSGDVWFGSSIVLKGKVTVAAKSGVKLEIPDRAVVENKNING 465


>3GUE-A nrPDB
          Length = 484

 Score =  309 bits (792), Expect = 2e-84,   Method: Compositional matrix adjust.
 Identities = 180/434 (41%), Positives = 260/434 (59%), Gaps = 21/434 (4%)

Query: 78  KSPNPDEVVKY-EIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLD 136
           KS +P E + + + I  + EN + L +  VLKLNGGLGT MG  GPKS+++V+ G TFLD
Sbjct: 50  KSISPVESLPFLQGIETKGENTALLRQAVVLKLNGGLGTGMGLNGPKSLLQVKNGQTFLD 109

Query: 137 LSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRS---FNQSRFPRVY 193
            +  Q+E+  +  + +VP +LMNSF+T  +T++ ++KY        S     Q+R P++ 
Sbjct: 110 FTALQLEHFRQVRNCNVPFMLMNSFSTSGETKNFLRKYPTLYEVFDSDIELMQNRVPKIR 169

Query: 194 KDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVD 253
           +D+  PV  E D P   W PPGHGD++  L+ SG+LD L+ +G   +F+SNGDNLGAT+D
Sbjct: 170 QDNFFPVTYEAD-PTCEWVPPGHGDVYTVLYSSGKLDYLLGKGYRYMFISNGDNLGATLD 228

Query: 254 LKILNHMIETGAEYIMELTDKTRADVKGGTLISYD------GQVR----LLEVAQVPKEH 303
           +++L++M E    ++ME+  +T +D KGG L   D      GQ R    L E AQ PKE 
Sbjct: 229 VRLLDYMHEKQLGFLMEVCRRTESDKKGGHLAYKDVIDETTGQTRRRFVLRESAQCPKED 288

Query: 304 IDEFKNIRKFTNFNTNNLWINLKAVKRLIES--SNLEMEIIPNQKTIT-RDGHEINVLQL 360
            D F+NI K   FNTNN+WINL  +K++++     L + ++ N KT+  +D     V QL
Sbjct: 289 EDSFQNIAKHCFFNTNNIWINLMELKKMMDEQLGVLRLPVMRNPKTVNPQDSQSTKVYQL 348

Query: 361 ETACGAAIRHFDGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRL-EHGSLKLDPSRFGPNP 419
           E A GAAI  FD +  VVVPR RF PVKTCSDLL ++SD +++ E   L L   R G  P
Sbjct: 349 EVAMGAAISLFDRSEAVVVPRERFAPVKTCSDLLALRSDAYQVTEDQRLVLCEERNGKPP 408

Query: 420 LIKL-GSHFKKVSGFNARIP-HIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKI 477
            I L G H+K + GF   +   +P + +   LT+ G V  G DV++RG V+I       +
Sbjct: 409 AIDLDGEHYKMIDGFEKLVKGGVPSLRQCTSLTVRGLVEFGADVSVRGNVVIKNLKEEPL 468

Query: 478 DIPNGSILENVVVT 491
            I +G +L+N VV 
Sbjct: 469 IIGSGRVLDNEVVV 482


>4M2B-A nrPDB
          Length = 505

 Score =  273 bits (698), Expect = 1e-73,   Method: Compositional matrix adjust.
 Identities = 158/416 (37%), Positives = 239/416 (57%), Gaps = 26/416 (6%)

Query: 101 LSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNS 160
           L    VLKLNGGLGT MG    K+++EV++G TFLD +  Q++YL +     +  +LM+S
Sbjct: 73  LQSTVVLKLNGGLGTGMGLCDAKTLLEVKDGKTFLDFTALQVQYLRQHCSEHLRFMLMDS 132

Query: 161 FNTDKDTEHLIKKYSANRIRI----RSFNQSRFPRVYKDSLLPVPTEYDSPLDAWYPPGH 216
           FNT   T+  +K       ++        Q++ P++ +D+L P     ++P   W PPGH
Sbjct: 133 FNTSASTKSFLKARYPWLYQVFDSEVELMQNQVPKILQDTLEPAAWA-ENPAYEWAPPGH 191

Query: 217 GDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTR 276
           GD++ +L+ SG+L  L+ QG   +FVSNGDNLGAT+D ++L +M +   +++ME+  +T 
Sbjct: 192 GDIYTALYGSGKLQELVEQGYRYMFVSNGDNLGATIDKRVLAYMEKEKIDFLMEVCRRTE 251

Query: 277 ADVKGGTLI-------SYDGQ-------VRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLW 322
           +D KGG L          DGQ       + L E AQ PK  ++ F++I K++ FNTNNLW
Sbjct: 252 SDKKGGHLARQTVYVKGKDGQPDAEKRVLDLRESAQCPKADMESFQDINKYSFFNTNNLW 311

Query: 323 INLKAVKRLIE--SSNLEMEIIPNQKTI-TRDGHEINVLQLETACGAAIRHFDGAHGVVV 379
           I L  +   ++     L + +I N+KT+ + +     V QLETA GAAI  F+ A  +VV
Sbjct: 312 IRLPVLLETMQEHGGTLPLPVIRNEKTVDSSNSASPKVYQLETAMGAAIAMFESASAIVV 371

Query: 380 PRSRFLPVKTCSDLLLVKSDLFRL-EHGSLKLDPSRFGPNPLIKLGS-HFKKVSGFNARI 437
           PRSRF PVKTC+DLL ++SD + + +   L LD    G  P++ L S H+K ++GF   +
Sbjct: 372 PRSRFAPVKTCADLLALRSDAYVVTDDFRLVLDDRCHGHPPVVDLDSAHYKMMNGFEKLV 431

Query: 438 PH-IPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSD-GHKIDIPNGSILENVVVT 491
            H +P +VE   +T+ G V  G    L GTV I  +D      IP+G+ L +   +
Sbjct: 432 QHGVPSLVECKRVTVKGLVQFGAGNVLTGTVTIENTDSASAFVIPDGAKLNDTTAS 487


>1VM8-A nrPDB
          Length = 534

 Score = 49.3 bits (116), Expect = 4e-06,   Method: Compositional matrix adjust.
 Identities = 65/292 (22%), Positives = 129/292 (44%), Gaps = 31/292 (10%)

Query: 32  NKLADSSKLD---DAARAKFENELDSFFTLFRRYLVEKSSRTTLE-WDKIKSPNPDEVV- 86
           N+L+++ +++   +     FE EL+SFF   R+ + E    +  E  D    P P +V+ 
Sbjct: 35  NELSEAQQMELYMELQAMNFE-ELNSFF---RKAIGEFDRSSHQEKVDARMEPVPRQVLG 90

Query: 87  -----KYEIISQQPENVSNLS--KLAVLKLNGGLGTSMGCVGPKSVIEVR--EGNTFLDL 137
                + ++ + + E +S +S  K+AVL L GG GT +G   PK + +V      T   +
Sbjct: 91  SATRDQEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSYPKGMYDVGLPSHKTLFQI 150

Query: 138 SVRQIEYLNRQYD------SDVPLLLMNSFNTDKDTEHLIKK---YSANRIRIRSFNQSR 188
              +I  L +  +        +P  +M S  T + T+    K   +   +  +  F Q  
Sbjct: 151 QAERILKLQQLAEKHHGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGM 210

Query: 189 FPRVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNL 248
            P +  D  + +  +    +    P G+G L+ +L     ++ +  +G   + V   DN+
Sbjct: 211 LPAMSFDGKIILEEKNKVSM---APDGNGGLYRALAAQNIVEDMEQRGICSIHVYCVDNI 267

Query: 249 GATV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQV 299
              V D + +   I+ GA+   ++ +KT      G +   DG  +++E +++
Sbjct: 268 LVKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEI 319


>1JV1-A nrPDB
          Length = 505

 Score = 46.6 bits (109), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 63/290 (21%), Positives = 126/290 (43%), Gaps = 27/290 (9%)

Query: 32  NKLADSSKLDDAARAKFEN--ELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVV--- 86
           N+L ++ +++  A  +  N  EL+ FF        + S +  +  D    P P EV+   
Sbjct: 23  NELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV--DARMEPVPREVLGSA 80

Query: 87  ---KYEIISQQPENVSNLS--KLAVLKLNGGLGTSMGCVGPKSVIEVR--EGNTFLDLSV 139
              + ++ + + E +  +S  K+AVL L GG GT +G   PK + +V      T   +  
Sbjct: 81  TRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQA 140

Query: 140 RQIEYLNR---QYDSD---VPLLLMNSFNTDKDTEHLIKK---YSANRIRIRSFNQSRFP 190
            +I  L +   +Y  +   +P  +M S  T + T+    K   +   +  +  F Q   P
Sbjct: 141 ERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLP 200

Query: 191 RVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGA 250
            +  D  + +  +    +    P G+G L+ +L     ++ +  +G   + V   DN+  
Sbjct: 201 AMSFDGKIILEEKNKVSMA---PDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILV 257

Query: 251 TV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQV 299
            V D + +   I+ GA+   ++ +KT      G +   DG  +++E +++
Sbjct: 258 KVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEI 307


>4BMA-A nrPDB
          Length = 509

 Score = 43.5 bits (101), Expect = 2e-04,   Method: Compositional matrix adjust.
 Identities = 49/241 (20%), Positives = 101/241 (41%), Gaps = 19/241 (7%)

Query: 102 SKLAVLKLNGGLGTSMGCVGPKSVIEV--REGNTFLDLSVRQIEYLN------RQYDSDV 153
           +K+AV+ + GG GT +G   PK   ++      +   +   +I  L          ++ +
Sbjct: 127 NKVAVVLMAGGQGTRLGSSAPKGCFDIGLPSHKSLFQIQAERIAKLQLLAQRISGKEAVI 186

Query: 154 PLLLMNSFNTDKDTEHLI---KKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDA 210
           P  +M S  T K TE      K +  N+  +  F Q   P +  +  + + +++     A
Sbjct: 187 PWYVMTSGPTRKPTEEFFEQHKYFGLNKSDVIIFEQGVLPCISNEGKILMESKFKV---A 243

Query: 211 WYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDN-LGATVDLKILNHMIETGAEYIM 269
             P G+G ++++L  SG  + +  +G E +     DN L    D   +        +   
Sbjct: 244 VAPDGNGGIYQALLTSGVREDMRKRGIEHIHTYCVDNCLVKVADPVFIGFAASKQVDIAT 303

Query: 270 ELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHID----EFKNIRKFTNFNTNNLWINL 325
           ++  K  A    G ++  +G+  ++E +++ KE  +    +  ++ KF   N  N + + 
Sbjct: 304 KVVRKRNATESVGLILQKNGKPDVVEYSEIDKETAEAKDPKQPDVLKFRAANIVNHYYSF 363

Query: 326 K 326
           K
Sbjct: 364 K 364


>3OC9-A nrPDB
          Length = 405

 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 55/229 (24%), Positives = 98/229 (42%), Gaps = 28/229 (12%)

Query: 89  EIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSV----------IEVREGNTFLDLS 138
           E+ISQ         K A++   GG G+ +G   PK +          I        L L 
Sbjct: 29  ELISQ--------GKTALITPAGGQGSRLGFEHPKGMFVLPFEIPKSIFQMTSERLLRLQ 80

Query: 139 VRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKK---YSANRIRIRSFNQSRFPRV-YK 194
               EY + Q +  +   LM +  T ++  +  K+   +  +  +I  F Q   P V + 
Sbjct: 81  ELASEY-SHQKNVMIHWFLMTNEETIEEINNYFKEHQYFGLSSEQIHCFPQGMLPVVDFN 139

Query: 195 DSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDN-LGATVD 253
             +L    + D P  A  P GHG LF++L  +G L+ +  +G +     N DN L   VD
Sbjct: 140 GKILY--EKKDKPYMA--PNGHGGLFKALKDNGILEFMNEKGIKYSVAHNVDNILCKDVD 195

Query: 254 LKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKE 302
             ++ +M    +E  +++  K   + K G L+    +++++E  ++  E
Sbjct: 196 PNMIGYMDLLQSEICIKIVKKGFKEEKVGVLVKEQERIKVVEYTELTDE 244


>2YQJ-A nrPDB
          Length = 486

 Score = 35.8 bits (81), Expect = 0.044,   Method: Compositional matrix adjust.
 Identities = 39/147 (26%), Positives = 67/147 (45%), Gaps = 15/147 (10%)

Query: 103 KLAVLKLNGGLGTSMGCVGPKSV--IEVREGNTFLDLS---VRQIEYLNRQY--DSDVPL 155
           ++AVL + GG GT +G   PK    IE+    +   +    + +IE L +QY   +  P+
Sbjct: 103 EVAVLLMAGGQGTRLGSSAPKGCFNIELPSQKSLFQIQAEKILKIEQLAQQYLKSTKKPI 162

Query: 156 L---LMNSFNTDKDTEHLI---KKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLD 209
           +   +M S  T   TE        +  N  ++  FNQ   P  +      +  E  + + 
Sbjct: 163 INWYIMTSGPTRNATESFFIENNYFGLNSHQVIFFNQGTLP-CFNLQGNKILLELKNSI- 220

Query: 210 AWYPPGHGDLFESLHVSGELDALIAQG 236
              P G+G L+++L  +G LD L ++G
Sbjct: 221 CQSPDGNGGLYKALKDNGILDDLNSKG 247


>1LFW-A nrPDB
          Length = 470

 Score = 31.6 bits (70), Expect = 0.93,   Method: Compositional matrix adjust.
 Identities = 28/108 (25%), Positives = 49/108 (45%), Gaps = 13/108 (12%)

Query: 254 LKILNHM--IETGAEYI-----MELTDKTR------ADVKGGTLISYDGQVRLLEVAQVP 300
           L I+ HM  +  G  +      ME+ ++ R      AD KG +L +Y G + L E    P
Sbjct: 82  LGIIGHMDVVPAGEGWTRDPFKMEIDEEGRIYGRGSADDKGPSLTAYYGMLLLKEAGFKP 141

Query: 301 KEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTI 348
           K+ ID      + TN+   + ++  +    ++ S + E  II  ++ I
Sbjct: 142 KKKIDFVLGTNEETNWVGIDYYLKHEPTPDIVFSPDAEYPIINGEQGI 189


>2N5T-A nrPDB
          Length = 575

 Score = 31.2 bits (69), Expect = 0.98,   Method: Compositional matrix adjust.
 Identities = 20/69 (28%), Positives = 34/69 (49%), Gaps = 1/69 (1%)

Query: 318 TNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQ-LETACGAAIRHFDGAHG 376
           TN +   ++AV+  + S   E+  + +   IT DGH++ V   + T         +GA G
Sbjct: 232 TNEVIDKMRAVQEQVASEKAELAKLKDLPAITLDGHQVEVCANIGTVRDVEGAERNGAEG 291

Query: 377 VVVPRSRFL 385
           V + R+ FL
Sbjct: 292 VGLYRTEFL 300


>4ZBK-B nrPDB
          Length = 189

 Score = 30.8 bits (68), Expect = 1.6,   Method: Compositional matrix adjust.
 Identities = 22/79 (27%), Positives = 34/79 (43%), Gaps = 7/79 (8%)

Query: 284 LISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIESSNLEMEIIP 343
           ++  DGQVR++ V       I     +    N     LW     VKR +E   L  +++P
Sbjct: 78  MVGQDGQVRMV-VGAAGGTQITTATALAIIYN-----LWFGYD-VKRAVEEPRLHNQLLP 130

Query: 344 NQKTITRDGHEINVLQLET 362
           N  T+ R+  +     LET
Sbjct: 131 NVTTVERNIDQAVTAALET 149


>5JAA-A nrPDB
          Length = 103

 Score = 29.6 bits (65), Expect = 3.4,   Method: Compositional matrix adjust.
 Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%)

Query: 63  LVEKSSRTTLEWDKIKS-PNPDEVVKYEIISQQPENVSNLSKL 104
           L+  SSRT   W++ +S PN   V   +++ + PE +S++++L
Sbjct: 61  LLHTSSRTLENWEQGRSVPNGQAVTLLKLVQRHPETLSHIAEL 103


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

2I5K-A nrPDB                                                          754   0.0  
5WEG-A nrPDB                                                          640   0.0  
2Q4J-A nrPDB                                                          637   0.0  
3R2W-A nrPDB                                                          627   e-180
3GUE-A nrPDB                                                          564   e-161
4M2B-A nrPDB                                                          530   e-151
1JV1-A nrPDB                                                          329   1e-90
1VM8-A nrPDB                                                          326   2e-89
4BMA-A nrPDB                                                          280   1e-75

Sequences not found previously or not previously below threshold:

2YQJ-A nrPDB                                                          194   7e-50
3OC9-A nrPDB                                                          141   8e-34
4BQH-A nrPDB                                                          135   4e-32
3OH0-A nrPDB                                                           69   5e-12
4PJ1-A nrPDB                                                           35   0.093
1JNE-A nrPDB                                                           35   0.093
4MYB-A nrPDB                                                           33   0.35 
1Y7H-A nrPDB                                                           32   0.54 
4CVH-A nrPDB                                                           32   0.65 
5H7J-A nrPDB                                                           31   1.3  
3PMO-A nrPDB                                                           30   1.9  
5X7Y-A nrPDB                                                           30   2.7  
1BYG-A nrPDB                                                           29   5.3  
1SVT-O nrPDB                                                           28   9.4  
3PS9-A nrPDB                                                           28   9.9  

>2I5K-A nrPDB
          Length = 488

 Score =  754 bits (1946), Expect = 0.0,   Method: Composition-based stats.
 Identities = 488/488 (100%), Positives = 488/488 (100%)

Query: 12  TYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTT 71
           TYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTT
Sbjct: 1   TYAFESNTNSVAASQMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTT 60

Query: 72  LEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREG 131
           LEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREG
Sbjct: 61  LEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREG 120

Query: 132 NTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPR 191
           NTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPR
Sbjct: 121 NTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPR 180

Query: 192 VYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT 251
           VYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT
Sbjct: 181 VYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT 240

Query: 252 VDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIR 311
           VDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIR
Sbjct: 241 VDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIR 300

Query: 312 KFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHF 371
           KFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHF
Sbjct: 301 KFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHF 360

Query: 372 DGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVS 431
           DGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVS
Sbjct: 361 DGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPNPLIKLGSHFKKVS 420

Query: 432 GFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT 491
           GFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT
Sbjct: 421 GFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT 480

Query: 492 GNLQILEH 499
           GNLQILEH
Sbjct: 481 GNLQILEH 488


>5WEG-A nrPDB
          Length = 476

 Score =  640 bits (1651), Expect = 0.0,   Method: Composition-based stats.
 Identities = 260/468 (55%), Positives = 338/468 (72%), Gaps = 16/468 (3%)

Query: 31  LNKL-ADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYE 89
           L+KL A+ +KLD  +    ENE   F +L  RYL  ++ +  +EW KI++P  + VV Y+
Sbjct: 15  LDKLRAEVAKLDQIS----ENEKAGFISLVSRYLSGEAEQ--IEWSKIQTPTDEVVVPYD 68

Query: 90  IISQQPENVSNLSKLAVLKL----NGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYL 145
            ++  PE++    KL    +    NGGLGT+MGC GPKSVIEVR G TFLDL V QIE L
Sbjct: 69  TLASPPEDLEETKKLLDKLVVLKLNGGLGTTMGCTGPKSVIEVRNGFTFLDLIVIQIESL 128

Query: 146 NRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYD 205
           N++Y   VPLLLMNSFNT  DT+ +++KYS + I I +FNQS++PR+  +  LP+P++  
Sbjct: 129 NKKYGCSVPLLLMNSFNTHDDTQKIVEKYSNSNIEIHTFNQSQYPRIVTEDFLPLPSKGK 188

Query: 206 SPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGA 265
           S  D WYPPGHGD+F SL+ SG+LD L+AQG+E +F++N DNLGA VD+KILNH+I    
Sbjct: 189 SGKDGWYPPGHGDVFPSLNNSGKLDILLAQGKEYVFIANSDNLGAIVDIKILNHLINNQN 248

Query: 266 EYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINL 325
           EY ME+T KT ADVKGGTLISY+G+V+LLE+AQVP EH++EFK+I KF  FNTNNLW+NL
Sbjct: 249 EYCMEVTPKTLADVKGGTLISYEGRVQLLEIAQVPDEHVNEFKSIEKFKIFNTNNLWVNL 308

Query: 326 KAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPRSRFL 385
           KA+KRL+E+  L+MEIIPN K +  DG  + VLQLETA GAAIR FD A G+ VPRSRFL
Sbjct: 309 KAIKRLVEAEALKMEIIPNPKEV--DG--VKVLQLETAAGAAIRFFDKAIGINVPRSRFL 364

Query: 386 PVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGP-NPLIKLGSHFKKVSGFNARIPHIPKIV 444
           PVK  SDLLLV+SDL+ L  G +  +P+R  P NP I+LG  FKKV+ F AR   IP IV
Sbjct: 365 PVKATSDLLLVQSDLYTLVDGFVIRNPARANPANPSIELGPEFKKVANFLARFKSIPSIV 424

Query: 445 ELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTG 492
           ELD L ++G+V+ G  +TL+G V I    G K++IP+G++LEN  V G
Sbjct: 425 ELDSLKVSGDVWFGSGITLKGKVTITAKSGVKLEIPDGAVLENKDVNG 472


>2Q4J-A nrPDB
          Length = 469

 Score =  637 bits (1642), Expect = 0.0,   Method: Composition-based stats.
 Identities = 241/472 (51%), Positives = 327/472 (69%), Gaps = 21/472 (4%)

Query: 26  QMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEV 85
           Q+++A++ L + S          E+E   F +L  RYL  ++    +EW KI++P  + V
Sbjct: 10  QLKSAVDGLTEMS----------ESEKSGFISLVSRYLSGEAQ--HIEWSKIQTPTDEIV 57

Query: 86  VKYEIISQQPENVSNLSKLAVLKL----NGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQ 141
           V YE ++   ++V+    L    +    NGGLGT+MGC GPKSVIEVR+G TFLDL V Q
Sbjct: 58  VPYEKMTPVSQDVAETKNLLDKLVVLKLNGGLGTTMGCTGPKSVIEVRDGLTFLDLIVIQ 117

Query: 142 IEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVP 201
           IE LN +Y   VPL+LMNSFNT  DT  +++KY+ + + I +FNQS++PRV  D  +P P
Sbjct: 118 IENLNNKYGCKVPLVLMNSFNTHDDTHKIVEKYTNSNVDIHTFNQSKYPRVVADEFVPWP 177

Query: 202 TEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMI 261
           ++  +  + WYPPGHGD+F +L  SG+LD  ++QG+E +FV+N DNLGA VDL IL H+I
Sbjct: 178 SKGKTDKEGWYPPGHGDVFPALMNSGKLDTFLSQGKEYVFVANSDNLGAIVDLTILKHLI 237

Query: 262 ETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNL 321
           +   EY ME+T KT ADVKGGTLISY+G+V+LLE+AQVP EH++EFK+I KF  FNTNNL
Sbjct: 238 QNKNEYCMEVTPKTLADVKGGTLISYEGKVQLLEIAQVPDEHVNEFKSIEKFKIFNTNNL 297

Query: 322 WINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLETACGAAIRHFDGAHGVVVPR 381
           W+NLKA+K+L+E+  L+MEIIPN K +  DG  + VLQLETA GAAIR FD A GV VPR
Sbjct: 298 WVNLKAIKKLVEADALKMEIIPNPKEV--DG--VKVLQLETAAGAAIRFFDNAIGVNVPR 353

Query: 382 SRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGP-NPLIKLGSHFKKVSGFNARIPHI 440
           SRFLPVK  SDLLLV+SDL+ L  G +  + +R  P NP I+LG  FKKV+ F +R   I
Sbjct: 354 SRFLPVKASSDLLLVQSDLYTLVDGFVTRNKARTNPSNPSIELGPEFKKVATFLSRFKSI 413

Query: 441 PKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVTG 492
           P IVELD L ++G+V+ G  + L+G V +    G K++IP+ +++EN  + G
Sbjct: 414 PSIVELDSLKVSGDVWFGSSIVLKGKVTVAAKSGVKLEIPDRAVVENKNING 465


>3R2W-A nrPDB
          Length = 528

 Score =  627 bits (1617), Expect = e-180,   Method: Composition-based stats.
 Identities = 268/498 (53%), Positives = 363/498 (72%), Gaps = 26/498 (5%)

Query: 23  AASQMRNALNKLADSSK-------LDDAARAKFEN---ELDSFFTLFRRYLVEKSSRTTL 72
            ASQ +  + +  + S        L  A+  +FE+   +LD F  LF R+L EK    ++
Sbjct: 36  GASQFQEVIRQELELSVKKELEKILTTASSHEFEHTKKDLDGFRKLFHRFLQEKGP--SV 93

Query: 73  EWDKIKSPNPDEVVKYEIISQQ--PENVSN-LSKLAVLKLNGGLGTSMGCVGPKSVIEVR 129
           +W KI+ P  D +  YE I  +  P+N+S+ L+KL V+KLNGGLGTSMGC GPKS+I VR
Sbjct: 94  DWGKIQRPPEDSIQPYEKIKARGLPDNISSVLNKLVVVKLNGGLGTSMGCKGPKSLIGVR 153

Query: 130 EGNTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRF 189
             NTFLDL+V+QIE+LN+ Y++DVPL+LMNSFNTD+DT+ +++KY+  R++I +FNQSR+
Sbjct: 154 NENTFLDLTVQQIEHLNKTYNTDVPLVLMNSFNTDEDTKKILQKYNHCRVKIYTFNQSRY 213

Query: 190 PRVYKDSLLPVPTEYDSP---LDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGD 246
           PR+ K+SLLPV  +        +AWYPPGHGD++ S + SG LD  I +G+E +FVSN D
Sbjct: 214 PRINKESLLPVAKDVSYSGENTEAWYPPGHGDIYASFYNSGLLDTFIGEGKEYIFVSNID 273

Query: 247 NLGATVDLKILNHMIE----TGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKE 302
           NLGATVDL ILNH++        E++ME+T+KTRADVKGGTL  Y+G++RL+E+AQVPK 
Sbjct: 274 NLGATVDLYILNHLMNPPNGKRCEFVMEVTNKTRADVKGGTLTQYEGKLRLVEIAQVPKA 333

Query: 303 HIDEFKNIRKFTNFNTNNLWINLKAVKRLIESSNLEMEIIPNQKTITRDGHEINVLQLET 362
           H+DEFK++ KF  FNTNNLWI+L AVKRL E + ++MEII N KT+  DG  +NV+QLET
Sbjct: 334 HVDEFKSVSKFKIFNTNNLWISLAAVKRLQEQNAIDMEIIVNAKTL--DGG-LNVIQLET 390

Query: 363 ACGAAIRHFDGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRLEHGSLKLDPSRFGPN-PLI 421
           A GAAI+ F+ + G+ VPRSRFLPVKT SDLLLV S+L+ L  GSL +   R  P  PL+
Sbjct: 391 AVGAAIKSFENSLGINVPRSRFLPVKTTSDLLLVMSNLYSLNAGSLTMSEKREFPTVPLV 450

Query: 422 KLGSHFKKVSGFNARIPHIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPN 481
           KLGS F KV  +  R   IP ++ELDHLT++G+V  GK+V+L+GTVII+ + G +IDIP 
Sbjct: 451 KLGSSFTKVQDYLRRFESIPDMLELDHLTVSGDVTFGKNVSLKGTVIIIANHGDRIDIPP 510

Query: 482 GSILENVVVTGNLQILEH 499
           G++LEN +V+GNL+IL+H
Sbjct: 511 GAVLENKIVSGNLRILDH 528


>3GUE-A nrPDB
          Length = 484

 Score =  564 bits (1454), Expect = e-161,   Method: Composition-based stats.
 Identities = 187/477 (39%), Positives = 272/477 (57%), Gaps = 25/477 (5%)

Query: 35  ADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKY-EIISQ 93
           A  + L+    +  E E      L +  LV K     +     KS +P E + + + I  
Sbjct: 11  AALACLEKMQASGVE-EKCIHIFLIQHALVRKGETGYIP---EKSISPVESLPFLQGIET 66

Query: 94  QPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDV 153
           + EN + L +  VLKLNGGLGT MG  GPKS+++V+ G TFLD +  Q+E+  +  + +V
Sbjct: 67  KGENTALLRQAVVLKLNGGLGTGMGLNGPKSLLQVKNGQTFLDFTALQLEHFRQVRNCNV 126

Query: 154 PLLLMNSFNTDKDTEHLIKKYSANRIRI---RSFNQSRFPRVYKDSLLPVPTEYDSPLDA 210
           P +LMNSF+T  +T++ ++KY              Q+R P++ +D+  PV  E D P   
Sbjct: 127 PFMLMNSFSTSGETKNFLRKYPTLYEVFDSDIELMQNRVPKIRQDNFFPVTYEAD-PTCE 185

Query: 211 WYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIME 270
           W PPGHGD++  L+ SG+LD L+ +G   +F+SNGDNLGAT+D+++L++M E    ++ME
Sbjct: 186 WVPPGHGDVYTVLYSSGKLDYLLGKGYRYMFISNGDNLGATLDVRLLDYMHEKQLGFLME 245

Query: 271 LTDKTRADVKGGTLISYD------GQVR----LLEVAQVPKEHIDEFKNIRKFTNFNTNN 320
           +  +T +D KGG L   D      GQ R    L E AQ PKE  D F+NI K   FNTNN
Sbjct: 246 VCRRTESDKKGGHLAYKDVIDETTGQTRRRFVLRESAQCPKEDEDSFQNIAKHCFFNTNN 305

Query: 321 LWINLKAVKRLIES--SNLEMEIIPNQKTIT-RDGHEINVLQLETACGAAIRHFDGAHGV 377
           +WINL  +K++++     L + ++ N KT+  +D     V QLE A GAAI  FD +  V
Sbjct: 306 IWINLMELKKMMDEQLGVLRLPVMRNPKTVNPQDSQSTKVYQLEVAMGAAISLFDRSEAV 365

Query: 378 VVPRSRFLPVKTCSDLLLVKSDLFRL-EHGSLKLDPSRFGPNPLIKL-GSHFKKVSGFNA 435
           VVPR RF PVKTCSDLL ++SD +++ E   L L   R G  P I L G H+K + GF  
Sbjct: 366 VVPRERFAPVKTCSDLLALRSDAYQVTEDQRLVLCEERNGKPPAIDLDGEHYKMIDGFEK 425

Query: 436 RIP-HIPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVVVT 491
            +   +P + +   LT+ G V  G DV++RG V+I       + I +G +L+N VV 
Sbjct: 426 LVKGGVPSLRQCTSLTVRGLVEFGADVSVRGNVVIKNLKEEPLIIGSGRVLDNEVVV 482


>4M2B-A nrPDB
          Length = 505

 Score =  530 bits (1366), Expect = e-151,   Method: Composition-based stats.
 Identities = 167/491 (34%), Positives = 265/491 (53%), Gaps = 30/491 (6%)

Query: 27  MRNALNKLADSSKLDDAARAKFENELDSFFTLFRRY-LVEKSSRTTLEWDKIKSPNPDEV 85
           M N +  L+ +++         +       T   ++ +V K    ++    I     D +
Sbjct: 1   MENDMKSLSAAAQACVKKMRDAKVNEACIRTFIAQHVMVSKGETGSIPDSAIM--PVDSL 58

Query: 86  VKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYL 145
              + ++ + +N + L    VLKLNGGLGT MG    K+++EV++G TFLD +  Q++YL
Sbjct: 59  DALDSLTIECDN-AVLQSTVVLKLNGGLGTGMGLCDAKTLLEVKDGKTFLDFTALQVQYL 117

Query: 146 NRQYDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRI----RSFNQSRFPRVYKDSLLPVP 201
            +     +  +LM+SFNT   T+  +K       ++        Q++ P++ +D+L P  
Sbjct: 118 RQHCSEHLRFMLMDSFNTSASTKSFLKARYPWLYQVFDSEVELMQNQVPKILQDTLEPAA 177

Query: 202 TEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMI 261
              ++P   W PPGHGD++ +L+ SG+L  L+ QG   +FVSNGDNLGAT+D ++L +M 
Sbjct: 178 WA-ENPAYEWAPPGHGDIYTALYGSGKLQELVEQGYRYMFVSNGDNLGATIDKRVLAYME 236

Query: 262 ETGAEYIMELTDKTRADVKGGTLIS-------YDGQV-------RLLEVAQVPKEHIDEF 307
           +   +++ME+  +T +D KGG L          DGQ         L E AQ PK  ++ F
Sbjct: 237 KEKIDFLMEVCRRTESDKKGGHLARQTVYVKGKDGQPDAEKRVLDLRESAQCPKADMESF 296

Query: 308 KNIRKFTNFNTNNLWINLKAVKRLIE--SSNLEMEIIPNQKTI-TRDGHEINVLQLETAC 364
           ++I K++ FNTNNLWI L  +   ++     L + +I N+KT+ + +     V QLETA 
Sbjct: 297 QDINKYSFFNTNNLWIRLPVLLETMQEHGGTLPLPVIRNEKTVDSSNSASPKVYQLETAM 356

Query: 365 GAAIRHFDGAHGVVVPRSRFLPVKTCSDLLLVKSDLFRL-EHGSLKLDPSRFGPNPLIKL 423
           GAAI  F+ A  +VVPRSRF PVKTC+DLL ++SD + + +   L LD    G  P++ L
Sbjct: 357 GAAIAMFESASAIVVPRSRFAPVKTCADLLALRSDAYVVTDDFRLVLDDRCHGHPPVVDL 416

Query: 424 GS-HFKKVSGFNARIPH-IPKIVELDHLTITGNVFLGKDVTLRGTVIIVCSD-GHKIDIP 480
            S H+K ++GF   + H +P +VE   +T+ G V  G    L GTV I  +D      IP
Sbjct: 417 DSAHYKMMNGFEKLVQHGVPSLVECKRVTVKGLVQFGAGNVLTGTVTIENTDSASAFVIP 476

Query: 481 NGSILENVVVT 491
           +G+ L +   +
Sbjct: 477 DGAKLNDTTAS 487


>1JV1-A nrPDB
          Length = 505

 Score =  329 bits (844), Expect = 1e-90,   Method: Composition-based stats.
 Identities = 64/326 (19%), Positives = 136/326 (41%), Gaps = 29/326 (8%)

Query: 32  NKLADSSKLDDAARAKFEN--ELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEVV--- 86
           N+L ++ +++  A  +  N  EL+ FF        + S +  +  D    P P EV+   
Sbjct: 23  NELEEAQQVELYAELQAMNFEELNFFFQKAIEGFNQSSHQKNV--DARMEPVPREVLGSA 80

Query: 87  ---KYEIISQQPENVSNL--SKLAVLKLNGGLGTSMGCVGPKSVIEV--REGNTFLDLSV 139
              + ++ + + E +  +  +K+AVL L GG GT +G   PK + +V      T   +  
Sbjct: 81  TRDQDQLQAWESEGLFQISQNKVAVLLLAGGQGTRLGVAYPKGMYDVGLPSRKTLFQIQA 140

Query: 140 RQIEYLNRQYD------SDVPLLLMNSFNTDKDTEHLIKK---YSANRIRIRSFNQSRFP 190
            +I  L +  +        +P  +M S  T + T+    K   +   +  +  F Q   P
Sbjct: 141 ERILKLQQVAEKYYGNKCIIPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLP 200

Query: 191 RVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGA 250
            +  D  + +  +    +    P G+G L+ +L     ++ +  +G   + V   DN+  
Sbjct: 201 AMSFDGKIILEEKNKVSM---APDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILV 257

Query: 251 TV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKN 309
            V D + +   I+ GA+   ++ +KT      G +   DG  +++E +++      +  +
Sbjct: 258 KVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRSS 317

Query: 310 IRK--FTNFNTNNLWINLKAVKRLIE 333
             +  F   N  N +  +  ++ ++ 
Sbjct: 318 DGRLLFNAGNIANHFFTVPFLRDVVN 343


>1VM8-A nrPDB
          Length = 534

 Score =  326 bits (835), Expect = 2e-89,   Method: Composition-based stats.
 Identities = 67/327 (20%), Positives = 139/327 (42%), Gaps = 31/327 (9%)

Query: 32  NKLADSSKLDDAARAKFEN--ELDSFFTLFRRYLVEKSSRTTLE-WDKIKSPNPDEVV-- 86
           N+L+++ +++     +  N  EL+SFF   R+ + E    +  E  D    P P +V+  
Sbjct: 35  NELSEAQQMELYMELQAMNFEELNSFF---RKAIGEFDRSSHQEKVDARMEPVPRQVLGS 91

Query: 87  ----KYEIISQQPENVSNL--SKLAVLKLNGGLGTSMGCVGPKSVIEV--REGNTFLDLS 138
               + ++ + + E +S +  +K+AVL L GG GT +G   PK + +V      T   + 
Sbjct: 92  ATRDQEQLQAWESEGLSQISQNKVAVLLLAGGQGTRLGVSYPKGMYDVGLPSHKTLFQIQ 151

Query: 139 VRQIEYLNRQYD------SDVPLLLMNSFNTDKDTEHLIKK---YSANRIRIRSFNQSRF 189
             +I  L +  +        +P  +M S  T + T+    K   +   +  +  F Q   
Sbjct: 152 AERILKLQQLAEKHHGNKCTIPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGML 211

Query: 190 PRVYKDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLG 249
           P +  D  + +  +    +    P G+G L+ +L     ++ +  +G   + V   DN+ 
Sbjct: 212 PAMSFDGKIILEEKNKVSM---APDGNGGLYRALAAQNIVEDMEQRGICSIHVYCVDNIL 268

Query: 250 ATV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFK 308
             V D + +   I+ GA+   ++ +KT      G +   DG  +++E +++         
Sbjct: 269 VKVADPRFIGFCIQKGADCGAKVVEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQRRS 328

Query: 309 NIRK--FTNFNTNNLWINLKAVKRLIE 333
           +  +  F   N  N +  +  +K ++ 
Sbjct: 329 SDGRLLFNAGNIANHFFTVPFLKDVVN 355


>4BMA-A nrPDB
          Length = 509

 Score =  280 bits (716), Expect = 1e-75,   Method: Composition-based stats.
 Identities = 60/317 (18%), Positives = 125/317 (39%), Gaps = 30/317 (9%)

Query: 37  SSKLDDAARAKFENELDSFFTLFRRYLVEKS--SRTTLEWDKIKSPNPDEVV-------K 87
             +L    R++  ++L SF  +    L +K+       +      P PD           
Sbjct: 51  VDELQTGERSQLFHQLSSFDPVRINELADKALNPPKADDGPASLEPLPDIATASILDSDP 110

Query: 88  YEIISQQPENVSNL--SKLAVLKLNGGLGTSMGCVGPKSVIEV--REGNTFLDLSVRQIE 143
            ++     E +  +  +K+AV+ + GG GT +G   PK   ++      +   +   +I 
Sbjct: 111 KDLEQWYEEGLKLVAGNKVAVVLMAGGQGTRLGSSAPKGCFDIGLPSHKSLFQIQAERIA 170

Query: 144 YLN------RQYDSDVPLLLMNSFNTDKDTEHLI---KKYSANRIRIRSFNQSRFPRVYK 194
            L          ++ +P  +M S  T K TE      K +  N+  +  F Q   P +  
Sbjct: 171 KLQLLAQRISGKEAVIPWYVMTSGPTRKPTEEFFEQHKYFGLNKSDVIIFEQGVLPCISN 230

Query: 195 DSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDN-LGATVD 253
           +  + + +++     A  P G+G ++++L  SG  + +  +G E +     DN L    D
Sbjct: 231 EGKILMESKFKV---AVAPDGNGGIYQALLTSGVREDMRKRGIEHIHTYCVDNCLVKVAD 287

Query: 254 LKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHID----EFKN 309
              +        +   ++  K  A    G ++  +G+  ++E +++ KE  +    +  +
Sbjct: 288 PVFIGFAASKQVDIATKVVRKRNATESVGLILQKNGKPDVVEYSEIDKETAEAKDPKQPD 347

Query: 310 IRKFTNFNTNNLWINLK 326
           + KF   N  N + + K
Sbjct: 348 VLKFRAANIVNHYYSFK 364


>2YQJ-A nrPDB
          Length = 486

 Score =  194 bits (493), Expect = 7e-50,   Method: Composition-based stats.
 Identities = 57/335 (17%), Positives = 128/335 (38%), Gaps = 32/335 (9%)

Query: 26  QMRNALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWDKIKSPNPDEV 85
           Q+    + L    + +   +     E     +   + + + S   +   +  + PN    
Sbjct: 20  QLFQYYDSLTIDQQQEFIDQLSTIEEPAKLISTVEQAI-QFSQTNSTSRNFTQLPNEQTA 78

Query: 86  VKYEIISQQPENVSNLS-------KLAVLKLNGGLGTSMGCVGPKSV--IEVREGNTFLD 136
              ++     +N + L        ++AVL + GG GT +G   PK    IE+    +   
Sbjct: 79  STLDLSKDILQNWTELGLKAIGNGEVAVLLMAGGQGTRLGSSAPKGCFNIELPSQKSLFQ 138

Query: 137 LSVRQI--------EYLNRQYDSDVPLLLMNSFNTDKDTEHLI---KKYSANRIRIRSFN 185
           +   +I        +YL       +   +M S  T   TE        +  N  ++  FN
Sbjct: 139 IQAEKILKIEQLAQQYLKSTKKPIINWYIMTSGPTRNATESFFIENNYFGLNSHQVIFFN 198

Query: 186 QSRFPRVY-KDSLLPVPTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSN 244
           Q   P    + + + +  +         P G+G L+++L  +G LD L ++G + + +  
Sbjct: 199 QGTLPCFNLQGNKILLELKNSICQS---PDGNGGLYKALKDNGILDDLNSKGIKHIHMYC 255

Query: 245 GDN-LGATVDLKILNHMIETGAEYIMELTDKTRADVKGGTLI--SYDGQVRLLEVAQVPK 301
            DN L    D   +   I    +   ++  K  A+   G ++    + +  ++E +++ +
Sbjct: 256 VDNCLVKVADPIFIGFAIAKKFDLATKVVRKRDANESVGLIVLDQDNQKPCVIEYSEISQ 315

Query: 302 EHIDEF--KNIRK--FTNFNTNNLWINLKAVKRLI 332
           E  ++   ++  K      N  N + +++ + ++I
Sbjct: 316 ELANKKDPQDSSKLFLRAANIVNHYYSVEFLNKMI 350


>3OC9-A nrPDB
          Length = 405

 Score =  141 bits (355), Expect = 8e-34,   Method: Composition-based stats.
 Identities = 48/259 (18%), Positives = 112/259 (43%), Gaps = 18/259 (6%)

Query: 103 KLAVLKLNGGLGTSMGCVGPKSVIEVREG--NTFLDLSVRQIEYLNR-------QYDSDV 153
           K A++   GG G+ +G   PK +  +      +   ++  ++  L         Q +  +
Sbjct: 35  KTALITPAGGQGSRLGFEHPKGMFVLPFEIPKSIFQMTSERLLRLQELASEYSHQKNVMI 94

Query: 154 PLLLMNSFNTDKDTEHLIK---KYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDA 210
              LM +  T ++  +  K    +  +  +I  F Q   P V  +  +    +    +  
Sbjct: 95  HWFLMTNEETIEEINNYFKEHQYFGLSSEQIHCFPQGMLPVVDFNGKILYEKKDKPYM-- 152

Query: 211 WYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGAT-VDLKILNHMIETGAEYIM 269
             P GHG LF++L  +G L+ +  +G +     N DN+    VD  ++ +M    +E  +
Sbjct: 153 -APNGHGGLFKALKDNGILEFMNEKGIKYSVAHNVDNILCKDVDPNMIGYMDLLQSEICI 211

Query: 270 ELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVK 329
           ++  K   + K G L+    +++++E  ++  E +++  +  +F  +N  ++ IN  +  
Sbjct: 212 KIVKKGFKEEKVGVLVKEQERIKVVEYTELTDE-LNKQLSNGEF-IYNCGHISINGYSTS 269

Query: 330 RLIESSNLEMEIIPNQKTI 348
            L +++  ++     +K +
Sbjct: 270 FLEKAAEYQLPYHIAKKKV 288


>4BQH-A nrPDB
          Length = 549

 Score =  135 bits (340), Expect = 4e-32,   Method: Composition-based stats.
 Identities = 71/349 (20%), Positives = 123/349 (35%), Gaps = 60/349 (17%)

Query: 19  TNSVAASQMR---NALNKLADSSKLDDAARAKFENELDSFFTLFRRYLVEKSSRTTLEWD 75
           TN +A    R   + L +  + SK    A        DSFF      +     R      
Sbjct: 43  TNELAGVDFRHFNDVLRESLEISKNCSTASLAEPPAKDSFFD-----ISSVDRRR----G 93

Query: 76  KIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVI---EVREGN 132
           + K     E V Y+ I           ++A L L GG GT +G   PK       +++  
Sbjct: 94  QAKRIKNLEAVGYKAI--------QKGQIAFLILAGGSGTRLGFDKPKGFFTCDGLQQRK 145

Query: 133 TFLDLSVRQIEYLN--------RQYDSDVPLLLMNSFNTDKDTEHLIK---KYSANRIRI 181
           +   +   +I                + V LL+M S   D +T+   +    +   R ++
Sbjct: 146 SLFMMHCEKIRRRQEIAESISGSGRKARVQLLVMTSGQNDAETQRFFEENSYFGLEREQV 205

Query: 182 RSFNQSRFPRVYKD-SLLPVPTEYDSPLDAWYPPGHGDLFESLHV--------------S 226
             F QS  P   ++   + +            P G+G +F +L                 
Sbjct: 206 HFFAQSSVPCYDENTGRIIMENRGRICA---APGGNGAVFAALAAPRATKDKDGTLQVKE 262

Query: 227 GELDALIAQGREILFVSNGDNLGATV-DLKILNHMIETGAEYIMELTDKTRADVKGGTLI 285
             L  L   G   + + N DNL A V D   + + IE  A  +++   K   D + G  +
Sbjct: 263 SLLQHLRKLGIAYVQIGNIDNLLANVADPVFIGYAIEEEAHVVVKTCPKRGPDERVGVFV 322

Query: 286 SYDGQVRLLEVAQVPK--EHIDEFKNIRKFTNFNTNN-----LWINLKA 327
              G+  ++E  ++    + ID+     KF   N ++      +++L A
Sbjct: 323 RASGKWGVVEYTEIGDRAKEIDDATGELKFNCANISSNLCSLHFMSLAA 371


>3OH0-A nrPDB
          Length = 641

 Score = 69.0 bits (167), Expect = 5e-12,   Method: Composition-based stats.
 Identities = 66/342 (19%), Positives = 112/342 (32%), Gaps = 45/342 (13%)

Query: 89  EIISQQPENVSNLSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQ 148
           E  + +    + L K   + + GGLG  +G    K  + V    T        + +  R 
Sbjct: 100 ERTALENAGTAMLCKTVFVLVAGGLGERLGYSSIKVSLPVETA-TNTTYLAYYLRWAQRV 158

Query: 149 YDSDVPLLLMNSFNTDKDTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPL 208
              +VP ++M S +T   T  L+++       +    Q +      DS   +  + ++  
Sbjct: 159 GGKEVPFVIMTSDDTHDRTLQLLRELQLEVPNLHVLKQGQVFCF-ADSAAHLALD-ETGK 216

Query: 209 DAWYPPGHGDLFESLHV------------------SGELDALIAQGREILFVSNGDNLGA 250
               P GHGD+   ++                      ++  +A G E +      N GA
Sbjct: 217 LLRKPHGHGDVHSLIYNATVKRDVVPDSGDGTATAQPLVNDWLAAGYESIVFIQDTNAGA 276

Query: 251 TVDLKI-LNHMIETGAEYIMELTDKTRADVKGGTLISY---DGQVRLLEVAQ-------- 298
           T+ + I L    E   +       +       G L       G   L+   +        
Sbjct: 277 TITIPISLALSAEHSLDMNFTCIPRV-PKEPIGLLCRTKKNSGDPWLVANVEYNVFAEVS 335

Query: 299 --VPKEHIDEFKNIRKFTNF--NTNNLWINLKA-VKRLIESSNLEMEIIPNQKTITRDGH 353
             + K+  DE  +   F+ F  + N L   L + V RL ES  +  E I N K       
Sbjct: 336 RALNKDGGDEVSDPTGFSPFPGSVNTLVFKLSSYVDRLRESHGIVPEFI-NPKYSDETRR 394

Query: 354 EINV-LQLETACGAAIRHFD----GAHGVVVPRSRFLPVKTC 390
                 ++E+        F        G V  R  + PVK  
Sbjct: 395 SFKKPARIESLMQDIALLFSEDDYRVGGTVFERFSYQPVKNS 436


>4PJ1-A nrPDB
          Length = 558

 Score = 34.7 bits (78), Expect = 0.093,   Method: Composition-based stats.
 Identities = 25/123 (20%), Positives = 45/123 (36%), Gaps = 12/123 (9%)

Query: 77  IKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGG------LGTSMGCVGPKSVIEVRE 130
           +       + + +  S+       ++++A +  NG       +  +M  VG K VI V++
Sbjct: 146 VMLAVDAVIAELKKQSKPVTTPEEIAQVATISANGDKEIGNIISDAMKKVGRKGVITVKD 205

Query: 131 GNTFLDLSVRQIEYLNRQYDSDVPLLLMNSFNTDKDTE-HLIKKYSANRIRIRSFNQSRF 189
           G T  D  +  IE +        P  +    NT K  +      Y     +  S  QS  
Sbjct: 206 GKTLND-ELEIIEGMKFDRGYISPYFI----NTSKGQKCEFQDAYVLLSEKKISSIQSIV 260

Query: 190 PRV 192
           P +
Sbjct: 261 PAL 263


>1JNE-A nrPDB
          Length = 420

 Score = 34.7 bits (78), Expect = 0.093,   Method: Composition-based stats.
 Identities = 27/122 (22%), Positives = 44/122 (36%), Gaps = 10/122 (8%)

Query: 193 YKDSLLPV--PTEYDSPLDAWYPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGA 250
             D L P   P E D     ++P G  D    L+   +++  ++QG    F SN  NLG 
Sbjct: 221 TFDFLTPARNPEEADYSAPIYHPDGSKDRLAHLNADFQVEYWLSQG----FPSNKINLGV 276

Query: 251 TVDLKILNHMIETGAEYIMELTDKTRADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNI 310
                      ++G E  + +  +T      G      G   LL  A++  +  +     
Sbjct: 277 ATYGNAWKLTKDSGLE-GVPVVPETSGPAPEGFQSQKPG---LLSYAEICGKLSNPQNQF 332

Query: 311 RK 312
            K
Sbjct: 333 LK 334


>4MYB-A nrPDB
          Length = 261

 Score = 32.8 bits (73), Expect = 0.35,   Method: Composition-based stats.
 Identities = 12/36 (33%), Positives = 17/36 (47%)

Query: 101 LSKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLD 136
           +S   V+    G+GT M    PK   ++  G T LD
Sbjct: 1   VSNKYVIIPAAGIGTRMQLDIPKQYYKLNNGKTILD 36


>1Y7H-A nrPDB
          Length = 268

 Score = 32.4 bits (72), Expect = 0.54,   Method: Composition-based stats.
 Identities = 25/108 (23%), Positives = 39/108 (36%), Gaps = 19/108 (17%)

Query: 123 KSVIEVREGN-TFLDLSV-----RQIEYLNRQYDSDVPLL-LMNSFNTDKDT----EHL- 170
           K ++E      T LDL+      R+IE L   YD  +PL+ LM S + D+        L 
Sbjct: 24  KPLLEAAGHKVTALDLAASGTDLRKIEELRTLYDYTLPLMELMESLSADEKVILVGHSLG 83

Query: 171 -------IKKYSANRIRIRSFNQSRFPRVYKDSLLPVPTEYDSPLDAW 211
                  ++KY                 V+  S +       +P + W
Sbjct: 84  GMNLGLAMEKYPQKIYAAVFLAAFMPDSVHNSSFVLEQYNERTPAENW 131


>4CVH-A nrPDB
          Length = 411

 Score = 32.0 bits (71), Expect = 0.65,   Method: Composition-based stats.
 Identities = 17/82 (20%), Positives = 31/82 (37%), Gaps = 5/82 (6%)

Query: 102 SKLAVLKLNGGLGTSMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYDSDVPLLLMNSF 161
             +A +   GG G  MG   PK    + E      L    ++ L R       +++  + 
Sbjct: 5   QAVAAVLPAGGCGERMGVPTPKQFCPILER----PLISYTLQALERVCWIK-DIVVAVTG 59

Query: 162 NTDKDTEHLIKKYSANRIRIRS 183
              +  + +I+KY   RI +  
Sbjct: 60  ENMEVMKSIIQKYQHKRISLVE 81


>5H7J-A nrPDB
          Length = 743

 Score = 30.8 bits (68), Expect = 1.3,   Method: Composition-based stats.
 Identities = 21/95 (22%), Positives = 35/95 (36%), Gaps = 4/95 (4%)

Query: 56  FTLFRRYLVEKSSRTTLEWDKIKSPNPDEVVKYEIISQQPENVSNLSKLAVLKLNGGLGT 115
            T     +  KS      +  +  P PDE+         PE      K    KL      
Sbjct: 472 ITKSSPMVEGKSPNRHNRFYIVVEPMPDEIYNAIKEGIIPEGRVKNPKEVAKKLA---EL 528

Query: 116 SMGCVGPKSVIEVREGNTFLDLSVRQIEYLNRQYD 150
            M     + ++++  GN F+D + + ++YLN   D
Sbjct: 529 GMDYEIARGIVDIYNGNMFIDNT-KGVQYLNEVMD 562


>3PMO-A nrPDB
          Length = 372

 Score = 30.5 bits (67), Expect = 1.9,   Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 22/48 (45%), Gaps = 1/48 (2%)

Query: 453 GNVFLGKDVTLRGTVIIVCSDGHKIDIPNGSILENVV-VTGNLQILEH 499
           G V +G DV +     I         I NG  L+N + +  N+QI +H
Sbjct: 221 GGVTIGDDVEIGANTTIDRGALSDTLIGNGVKLDNQIMIAHNVQIGDH 268


>5X7Y-A nrPDB
          Length = 177

 Score = 29.7 bits (65), Expect = 2.7,   Method: Composition-based stats.
 Identities = 21/131 (16%), Positives = 44/131 (33%), Gaps = 14/131 (10%)

Query: 217 GDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGAEYIMELTDKTR 276
           GD +  L  S   + +   G   +FV + + L    +  ++  M         +++    
Sbjct: 21  GDWYSILLASDIKEKIEENGSMRVFVKDIEVLS---NSSLIFTMHTKVNGKCTKISLICN 77

Query: 277 ADVKGGTLISYDGQVRLLEVAQVPKEHIDEFKNIRKFTNFNTNNLWINLKAVKRLIESSN 336
              K G          L  + +   E          +  F+ NN  +N +   +L+E   
Sbjct: 78  KTEKDGEYDVVHDGYNLFRIIETAYED---------YIIFHLNN--VNQEQEFQLMELYG 126

Query: 337 LEMEIIPNQKT 347
            + ++ P  K 
Sbjct: 127 RKPDVSPKVKE 137


>1BYG-A nrPDB
          Length = 278

 Score = 28.9 bits (63), Expect = 5.3,   Method: Composition-based stats.
 Identities = 15/67 (22%), Positives = 26/67 (38%), Gaps = 4/67 (5%)

Query: 166 DTEHLIKKYSANRIRIRSFNQSRFPRVYKDSLLP-VPTEYDSPLDAWYPPGHGDLFESLH 224
            T+  +  +      I SF +  +PR+    ++P V   Y        PP    ++E + 
Sbjct: 192 STKSDVWSFGILLWEIYSFGRVPYPRIPLKDVVPRVEKGYKMDAPDGCPPA---VYEVMK 248

Query: 225 VSGELDA 231
               LDA
Sbjct: 249 NCWHLDA 255


>1SVT-O nrPDB
          Length = 97

 Score = 28.1 bits (61), Expect = 9.4,   Method: Composition-based stats.
 Identities = 10/31 (32%), Positives = 15/31 (48%)

Query: 460 DVTLRGTVIIVCSDGHKIDIPNGSILENVVV 490
            + L G+     + G  + + NG ILEN  V
Sbjct: 24  GIVLTGSAAAKSTRGEVLAVGNGRILENGEV 54


>3PS9-A nrPDB
          Length = 676

 Score = 28.1 bits (61), Expect = 9.9,   Method: Composition-based stats.
 Identities = 14/54 (25%), Positives = 20/54 (37%), Gaps = 1/54 (1%)

Query: 212 YPPGHGDLFESLHVSGELDALIAQGREILFVSNGDNLGATVDLKILNHMIETGA 265
           YP G G L  +      L+    QG +I +     N     D  +LN   +  A
Sbjct: 408 YPQG-GWLCPAELTRNVLELAQQQGLQIYYQYQLQNFSRKDDCWLLNFAGDQQA 460


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.309    0.130    0.328 

Lambda     K      H
   0.267   0.0399    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,381,832
Number of Sequences: 36641
Number of extensions: 667851
Number of successful extensions: 2072
Number of sequences better than 10.0: 26
Number of HSP's better than 10.0 without gapping: 26
Number of HSP's successfully gapped in prelim test: 20
Number of HSP's that attempted gapping in prelim test: 1949
Number of HSP's gapped (non-prelim): 47
length of query: 499
length of database: 10,336,785
effective HSP length: 101
effective length of query: 398
effective length of database: 6,636,044
effective search space: 2641145512
effective search space used: 2641145512
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.2 bits)
S2: 61 (28.1 bits)