BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P32565 (945 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4ADY-A nrPDB 1944 0.0 6MSE-U nrPDB 678 0.0 5VHF-U nrPDB 590 e-169 5LN3-Z nrPDB 73 5e-13 5T0J-f nrPDB 72 1e-12 5WVI-Z nrPDB 63 6e-10 5K3G-A nrPDB 33 0.85 5X68-A nrPDB 31 3.1 2IJD-1 nrPDB 30 3.3 1GMJ-A nrPDB 30 6.6 3LLL-A nrPDB 29 8.3 3HAI-A nrPDB 29 8.6 >4ADY-A nrPDB Length = 963 Score = 1944 bits (5035), Expect = 0.0, Method: Compositional matrix adjust. Identities = 944/944 (100%), Positives = 944/944 (100%) Query: 2 SLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMA 61 SLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMA Sbjct: 13 SLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMA 72 Query: 62 ALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDE 121 ALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDE Sbjct: 73 ALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDE 132 Query: 122 QFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSE 181 QFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSE Sbjct: 133 QFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSE 192 Query: 182 NVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL 241 NVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL Sbjct: 193 NVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL 252 Query: 242 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNT 301 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNT Sbjct: 253 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNT 312 Query: 302 FLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQN 361 FLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQN Sbjct: 313 FLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQN 372 Query: 362 WAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD 421 WAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD Sbjct: 373 WAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD 432 Query: 422 YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAA 481 YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAA Sbjct: 433 YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAA 492 Query: 482 ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLA 541 ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLA Sbjct: 493 ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLA 552 Query: 542 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTT 601 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTT Sbjct: 553 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTT 612 Query: 602 VPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALS 661 VPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALS Sbjct: 613 VPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALS 672 Query: 662 MILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAD 721 MILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAD Sbjct: 673 MILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAD 732 Query: 722 TGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDA 781 TGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDA Sbjct: 733 TGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDA 792 Query: 782 FSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERET 841 FSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERET Sbjct: 793 FSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERET 852 Query: 842 NKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNG 901 NKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNG Sbjct: 853 NKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNG 912 Query: 902 VVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA 945 VVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA Sbjct: 913 VVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA 956 >6MSE-U nrPDB Length = 953 Score = 678 bits (1749), Expect = 0.0, Method: Compositional matrix adjust. Identities = 394/967 (40%), Positives = 574/967 (59%), Gaps = 93/967 (9%) Query: 3 LTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMAA 62 +T+AA +++LL E++ +K +AL +N VV+ W+EIS + IE LY+D+ F R+ AA Sbjct: 2 ITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAA 61 Query: 63 LIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDEQ 122 L+ASKV+Y+LG +E ++ YAL A D F++++ S++VETI++K I+ Y ++ + E Sbjct: 62 LVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEG 121 Query: 123 FYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSEN 182 K ID +L I +M ++CL + K A+GIALE RLD+ E K+ L+ + Sbjct: 122 --EKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFE---KTILESNDVP-- 174 Query: 183 VKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQLF 242 ++ Y L L ++ + N +FR+ +LR MN+ D++ + + ++ L+D + Sbjct: 175 -GMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDIL 233 Query: 243 KKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPA----------------- 285 +KL +E++ ++ QI FDL SASQQ L ++ L G A Sbjct: 234 EKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKD 293 Query: 286 -------------------------------LLNILSGLPTCDYYNTFLLNNKNIDIGLL 314 ++ ILSG + + FL+ N N D+ +L Sbjct: 294 SDSMETEEKTSSAFVGKTPEASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMIL 353 Query: 315 NKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVI 374 +K ++ + S+ HTA +AN FMH GTT + F++ NL WL +A NWAKFTATASLGVI Sbjct: 354 KNTKDAV--RNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVI 411 Query: 375 HKGNLLEGKKVMAPYLP-GSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNIIVENSGT 433 HKG+ E ++MA YLP + S + +GG LY LGLI+A G D DYL N + S Sbjct: 412 HKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASN- 470 Query: 434 SGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTG 493 D++ HG SLG+GLAAMG+A +VY+ LK LY D A +GEAA L +GL MLG+ Sbjct: 471 ------DIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSK 524 Query: 494 KPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAF 553 +AI DM Y+QETQH I RGLAVG+AL+ YGR E AD LI + + +LR G + Sbjct: 525 NAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMY 584 Query: 554 TIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTTVPRIVQLLSKSH 613 T+A+AY G+GNN A++RLLHVAVSD NDDVRRAAV +LGF+L R P +V LLS+S+ Sbjct: 585 TVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESY 644 Query: 614 NAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALSMILIQQTEKLNP 673 N HVR G A ALGI CAG G + AI++L+P+T DPV++VRQ A+IA ++I+IQQTE P Sbjct: 645 NPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCP 704 Query: 674 QVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENADTGTLDTKSVVGL 733 +V + + VI +KH + +AKFGA +AQGI++AGG NVTI L+ + TG SVVG+ Sbjct: 705 KVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQ-SRTGHTHMPSVVGV 763 Query: 734 VMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDAFSYPRMYEEASG 793 ++F+QFW+WFPL+HFLSL++TPT VIG+ D +PK Q K F+YP E Sbjct: 764 LVFTQFWFWFPLSHFLSLAYTPTCVIGLN-KDLKMPKVQYKSNCKPSTFAYPAPLEVPKE 822 Query: 794 KEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKEND 853 KE EKV+TAVLS TA+AK + K+ +K++ E + E ++ + Sbjct: 823 KEKEKVSTAVLSITAKAKKKEKEKEKKEEEKME-------------------VDEAEKKE 863 Query: 854 EEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVVVLRD-----R 908 E+ K + +DN R++P Q + ++ + R+ P + G+++L+D Sbjct: 864 EKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPETCRYQPFKPLS-IGGIIILKDTSEDIE 922 Query: 909 EPKEPVA 915 E EPVA Sbjct: 923 ELVEPVA 929 >5VHF-U nrPDB Length = 841 Score = 590 bits (1521), Expect = e-169, Method: Compositional matrix adjust. Identities = 353/874 (40%), Positives = 507/874 (58%), Gaps = 93/874 (10%) Query: 96 QFVETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALG 155 ++VETI++K I+ Y ++ + E K ID +L I +M ++CL + K A+G Sbjct: 1 EYVETIIAKCIDHYTKQCVENADLPEG--EKKPIDQRLEGIVNKMFQRCLDDHKYKQAIG 58 Query: 156 IALEGYRLDIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLM 215 IALE RLD+ E K+ L+ + ++ Y L L ++ + N +FR+ +LR M Sbjct: 59 IALETRRLDVFE---KTILESNDVP---GMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYM 112 Query: 216 NMPNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVT 275 N+ D++ + + ++ L+D + +KL +E++ ++ QI FDL SASQQ L ++ Sbjct: 113 NLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQ 172 Query: 276 ELTAQGYDPA------------------------------------------------LL 287 L G A ++ Sbjct: 173 NLRTVGTPIASVPGSTNTGTVPGSEKDSDSMETEEKTSSAFVGKTPEASPEPKDQTLKMI 232 Query: 288 NILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNS 347 ILSG + + FL+ N N D+ +L +K ++ + S+ HTA +AN FMH GTT + Sbjct: 233 KILSGEMAIELHLQFLIRNNNTDLMILKNTKDAV--RNSVCHTATVIANSFMHCGTTSDQ 290 Query: 348 FIKANLPWLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLP-GSRASSRFIKGGSLY 406 F++ NL WL +A NWAKFTATASLGVIHKG+ E ++MA YLP + S + +GG LY Sbjct: 291 FLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLY 350 Query: 407 GLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEAL 466 LGLI+A G D DYL N + S D++ HG SLG+GLAAMG+A +VY+ L Sbjct: 351 ALGLIHANHGGDIIDYLLNQLKNASN-------DIVRHGGSLGLGLAAMGTARQDVYDLL 403 Query: 467 KEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINY 526 K LY D A +GEAA L +GL MLG+ +AI DM Y+QETQH I RGLAVG+AL+ Y Sbjct: 404 KTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMY 463 Query: 527 GRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRA 586 GR E AD LI + + +LR G +T+A+AY G+GNN A++RLLHVAVSD NDDVRRA Sbjct: 464 GRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRA 523 Query: 587 AVIALGFVLLRDYTTVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTK 646 AV +LGF+L R P +V LLS+S+N HVR G A ALGI CAG G + AI++L+P+T Sbjct: 524 AVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTN 583 Query: 647 DPVDFVRQAAMIALSMILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIM 706 DPV++VRQ A+IA ++I+IQQTE P+V + + VI +KH + +AKFGA +AQGI+ Sbjct: 584 DPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGIL 643 Query: 707 NAGGRNVTIQLENADTGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQ 766 +AGG NVTI L+ + TG SVVG+++F+QFW+WFPL+HFLSL++TPT VIG+ D Sbjct: 644 DAGGHNVTISLQ-SRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLN-KDL 701 Query: 767 AIPKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEE 826 +PK Q K F+YP E KE EKV+TAVLS TA+AK + K+ +K++ E Sbjct: 702 KMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKME 761 Query: 827 EKKKEHEEKEKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIK 886 + E ++ +E+ K + +DN R++P Q + ++ + Sbjct: 762 -------------------VDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPE 802 Query: 887 DDRFVPVRKFKGNNGVVVLRD-----REPKEPVA 915 R+ P + G+++L+D E EPVA Sbjct: 803 TCRYQPFKPLS-IGGIIILKDTSEDIEELVEPVA 835 >5LN3-Z nrPDB Length = 908 Score = 73.2 bits (178), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 78/291 (26%), Positives = 128/291 (43%), Gaps = 33/291 (11%) Query: 297 DYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANL-PW 355 D Y T L NN+ S S +D + + A S NGF++A + + + W Sbjct: 347 DIYKTHLENNR------FGGSGSQVDS--ARMNLASSFVNGFVNAAFGQDKLLTDDGNKW 398 Query: 356 LGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGF 415 L K ++ +A ASLG+I ++ G + YL +S +IK G+L G++ +G Sbjct: 399 LYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYL---YSSEDYIKSGALLACGIVNSGV 455 Query: 416 GRDTTD----YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLY 471 R+ D L + ++ NS T + G+ G+GLA GS +V L V+ Sbjct: 456 -RNECDPALALLSDYVLHNSNT--------MRLGSIFGLGLAYAGSNREDVLTLLLPVM- 505 Query: 472 NDSATSGEAA---ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNI----TRGLAVGLALI 524 DS +S E A AL G+ +G+ + + E + R L +GL L Sbjct: 506 GDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLN 565 Query: 525 NYGRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVA 575 + G+ E + ++ + E + AYAG+GN V++LLH+ Sbjct: 566 HLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHIC 616 >5T0J-f nrPDB Length = 749 Score = 72.0 bits (175), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 78/291 (26%), Positives = 128/291 (43%), Gaps = 33/291 (11%) Query: 297 DYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANL-PW 355 D Y T L NN+ S S +D + + A S NGF++A + + + W Sbjct: 188 DIYKTHLENNR------FGGSGSQVDS--ARMNLASSFVNGFVNAAFGQDKLLTDDGNKW 239 Query: 356 LGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGF 415 L K ++ +A ASLG+I ++ G + YL +S +IK G+L G++ +G Sbjct: 240 LYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYL---YSSEDYIKSGALLACGIVNSGV 296 Query: 416 GRDTTD----YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLY 471 R+ D L + ++ NS T + G+ G+GLA GS +V L V+ Sbjct: 297 -RNECDPALALLSDYVLHNSNT--------MRLGSIFGLGLAYAGSNREDVLTLLLPVM- 346 Query: 472 NDSATSGEAA---ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNI----TRGLAVGLALI 524 DS +S E A AL G+ +G+ + + E + R L +GL L Sbjct: 347 GDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQTIMEKSETELKDTYARWLPLGLGLN 406 Query: 525 NYGRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVA 575 + G+ E + ++ + E + AYAG+GN V++LLH+ Sbjct: 407 HLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAYAGSGNVLKVQQLLHIC 457 >5WVI-Z nrPDB Length = 993 Score = 63.2 bits (152), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 70/272 (25%), Positives = 122/272 (44%), Gaps = 24/272 (8%) Query: 318 KSSLDGKFSLFHTA----------VSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTA 367 KS LD S+F +A S NGF++ G ++ I N W+ K + +A Sbjct: 359 KSHLDNSKSVFSSAGLDSAQQNLASSFVNGFLNLGYCNDKLIVDNDNWVYKTKGDGMTSA 418 Query: 368 TASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNII 427 AS+G I++ N L+G + + YL +K G+L G+G+ +G D ++ Sbjct: 419 VASIGSIYQWN-LDGLQQLDKYL---YVDEPEVKAGALLGIGISASGV-HDGEVEPALLL 473 Query: 428 VENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDS--ATSGEAAALGM 485 +++ T+ D + A LG+G+A GS N EV L + + + A+L + Sbjct: 474 LQDYVTNPDTKIS---SAAILGLGIAFAGSKNDEVLGLLLPIAASTDLPIETAAMASLAL 530 Query: 486 GLCMLGTGKPE---AIHDMFTYSQETQ-HGNITRGLAVGLALINYGRQELADDLITKMLA 541 +GT + +I D F + + R LA+ L ++ G+ E DD++ + A Sbjct: 531 AHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFLALALGILYMGQGEQVDDVLETISA 590 Query: 542 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLH 573 + + + AY GTG+ ++ LLH Sbjct: 591 IEHPMTSAIEVLVGSCAYTGTGDVLLIQDLLH 622 >5K3G-A nrPDB Length = 684 Score = 32.7 bits (73), Expect = 0.85, Method: Compositional matrix adjust. Identities = 22/66 (33%), Positives = 35/66 (53%), Gaps = 10/66 (15%) Query: 20 VKTYALE-------SINNVVDQLWSEISNELPDIEALYDDDTFSDREMAALIASK---VY 69 V TYALE ++ V DQL+ + P+ +L D FSDRE+ +++ + VY Sbjct: 578 VATYALEDGFMSSTQLDYVRDQLYFYLQKIRPNAVSLLDSWEFSDRELRSVLGRRDGHVY 637 Query: 70 YNLGEY 75 NL ++ Sbjct: 638 ENLFKW 643 >5X68-A nrPDB Length = 391 Score = 30.8 bits (68), Expect = 3.1, Method: Compositional matrix adjust. Identities = 23/94 (24%), Positives = 46/94 (48%), Gaps = 12/94 (12%) Query: 500 DMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTIALAY 559 D++ ++T+ TRG ++ LAL + GRQ L K + ++ ++ G + + Sbjct: 41 DVYEAREDTRVATFTRGRSINLALSHRGRQAL------KAVGLEDQIVSQGIPMRARMIH 94 Query: 560 AGTGNNSAV------KRLLHVAVSDSNDDVRRAA 587 + +G SA+ + +L V+ + N D+ AA Sbjct: 95 SLSGKKSAIPYGTKSQYILSVSRENLNKDLLTAA 128 >2IJD-1 nrPDB Length = 644 Score = 30.4 bits (67), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/67 (26%), Positives = 30/67 (44%), Gaps = 7/67 (10%) Query: 658 IALSMILIQQTEKLN-------PQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGG 710 + +++I +++ EK Q+ + N L V T+K+ GA QG +N GG Sbjct: 70 LEITIITLKRNEKFRDIRPHIPTQITETNDGVLIVNTSKYPNMYVPVGAVTEQGYLNLGG 129 Query: 711 RNVTIQL 717 R L Sbjct: 130 RQTARTL 136 >1GMJ-A nrPDB Length = 84 Score = 29.6 bits (65), Expect = 6.6, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 27/48 (56%) Query: 808 ARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKENDEE 855 ARAK + KK K KE E +KE E +K+ IK+ K+++++ Sbjct: 36 ARAKEQLAALKKHKENEISHHAKEIERLQKEIERHKQSIKKLKQSEDD 83 >3LLL-A nrPDB Length = 287 Score = 29.3 bits (64), Expect = 8.3, Method: Composition-based stats. Identities = 26/106 (24%), Positives = 46/106 (43%), Gaps = 7/106 (6%) Query: 779 EDAFSYPRMYEEASGKEVEKVATAVLSTTARAK---ARAKKTKKEKGPNEEEKKKEHEEK 835 ED F + KEVE A + K +R +K + N E+ KK ++ Sbjct: 120 EDGFRKAQKPWAKKLKEVEAAKKAHHTACKEEKLAISREANSKADPSLNPEQLKKLQDKI 179 Query: 836 EKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRY 881 EK K+ + +TK+ E+ K + P ++NM ++ Q ++ Sbjct: 180 EK----CKQDVLKTKDKYEKSLKELDQTTPQYMENMEQVFEQCQQF 221 >3HAI-A nrPDB Length = 308 Score = 29.3 bits (64), Expect = 8.6, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 52/116 (44%), Gaps = 11/116 (9%) Query: 779 EDAFSYPRMYEEASGKEVEKVATA---VLSTTARAKARAKKTKKEKGPNEEEKKKEHEEK 835 ED F + KE+E A A R +K E+ E++KK ++ Sbjct: 136 EDGFRKAQKPWAKKMKELEAAKKAYHLACKEEKLAMTREMNSKTEQSVTPEQQKKLQDKV 195 Query: 836 EKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQ----QSRYISFIKD 887 +K K+ +++T+E E+ ++ + P ++NM ++ Q + + + F+K+ Sbjct: 196 DK----CKQDVQKTQEKYEKVLEDVGKTTPQYMENMEQVFEQCQQFEEKRLVFLKE 247 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4ADY-A nrPDB 1483 0.0 6MSE-U nrPDB 1338 0.0 5VHF-U nrPDB 1181 0.0 5T0J-f nrPDB 319 3e-87 5LN3-Z nrPDB 319 3e-87 5WVI-Z nrPDB 292 4e-79 Sequences not found previously or not previously below threshold: 2NBW-A nrPDB 148 1e-35 6FEC-u nrPDB 38 0.022 3PDK-A nrPDB 35 0.14 2WN7-A nrPDB 35 0.18 6NOD-A nrPDB 34 0.30 3ZYY-X nrPDB 33 0.55 5N3U-A nrPDB 32 1.1 3JCR-F nrPDB 32 1.2 3IZY-P nrPDB 32 1.3 1YEY-A nrPDB 31 2.0 4OER-A nrPDB 31 2.4 3RQF-A nrPDB 31 2.5 2QAG-C nrPDB 30 3.3 4GFQ-A nrPDB 30 4.2 2H8F-A nrPDB 30 4.2 3JAX-A nrPDB 30 5.2 2OWY-A nrPDB 30 6.2 5W5C-E nrPDB 30 6.3 5OQL-K nrPDB 30 6.6 5YFP-B nrPDB 29 9.0 1WCM-D nrPDB 29 9.0 4RM9-A nrPDB 29 9.3 >4ADY-A nrPDB Length = 963 Score = 1483 bits (3839), Expect = 0.0, Method: Composition-based stats. Identities = 944/944 (100%), Positives = 944/944 (100%) Query: 2 SLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMA 61 SLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMA Sbjct: 13 SLTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMA 72 Query: 62 ALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDE 121 ALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDE Sbjct: 73 ALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDE 132 Query: 122 QFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSE 181 QFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSE Sbjct: 133 QFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSE 192 Query: 182 NVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL 241 NVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL Sbjct: 193 NVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL 252 Query: 242 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNT 301 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNT Sbjct: 253 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILSGLPTCDYYNT 312 Query: 302 FLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQN 361 FLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQN Sbjct: 313 FLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQN 372 Query: 362 WAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD 421 WAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD Sbjct: 373 WAKFTATASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD 432 Query: 422 YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAA 481 YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAA Sbjct: 433 YLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAA 492 Query: 482 ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLA 541 ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLA Sbjct: 493 ALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLA 552 Query: 542 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTT 601 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTT Sbjct: 553 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTT 612 Query: 602 VPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALS 661 VPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALS Sbjct: 613 VPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALS 672 Query: 662 MILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAD 721 MILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAD Sbjct: 673 MILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENAD 732 Query: 722 TGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDA 781 TGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDA Sbjct: 733 TGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDA 792 Query: 782 FSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERET 841 FSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERET Sbjct: 793 FSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERET 852 Query: 842 NKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNG 901 NKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNG Sbjct: 853 NKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNG 912 Query: 902 VVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA 945 VVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA Sbjct: 913 VVVLRDREPKEPVALIETVRQMKDVNAPLPTPFKVDDNVDFPSA 956 >6MSE-U nrPDB Length = 953 Score = 1338 bits (3463), Expect = 0.0, Method: Composition-based stats. Identities = 394/967 (40%), Positives = 574/967 (59%), Gaps = 93/967 (9%) Query: 3 LTTAAPLLALLRENQDSVKTYALESINNVVDQLWSEISNELPDIEALYDDDTFSDREMAA 62 +T+AA +++LL E++ +K +AL +N VV+ W+EIS + IE LY+D+ F R+ AA Sbjct: 2 ITSAAGIISLLDEDEPQLKEFALHKLNAVVNDFWAEISESVDKIEVLYEDEGFRSRQFAA 61 Query: 63 LIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVSKSIEMYVQEASKQYTKDEQ 122 L+ASKV+Y+LG +E ++ YAL A D F++++ S++VETI++K I+ Y ++ + E Sbjct: 62 LVASKVFYHLGAFEESLNYALGAGDLFNVNDNSEYVETIIAKCIDHYTKQCVENADLPEG 121 Query: 123 FYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSEN 182 K ID +L I +M ++CL + K A+GIALE RLD+ E K+ L+ + Sbjct: 122 --EKKPIDQRLEGIVNKMFQRCLDDHKYKQAIGIALETRRLDVFE---KTILESNDVP-- 174 Query: 183 VKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQLF 242 ++ Y L L ++ + N +FR+ +LR MN+ D++ + + ++ L+D + Sbjct: 175 -GMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYMNLEKPDFINVCQCLIFLDDPQAVSDIL 233 Query: 243 KKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPA----------------- 285 +KL +E++ ++ QI FDL SASQQ L ++ L G A Sbjct: 234 EKLVKEDNLLMAYQICFDLYESASQQFLSSVIQNLRTVGTPIASVPGSTNTGTVPGSEKD 293 Query: 286 -------------------------------LLNILSGLPTCDYYNTFLLNNKNIDIGLL 314 ++ ILSG + + FL+ N N D+ +L Sbjct: 294 SDSMETEEKTSSAFVGKTPEASPEPKDQTLKMIKILSGEMAIELHLQFLIRNNNTDLMIL 353 Query: 315 NKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVI 374 +K ++ + S+ HTA +AN FMH GTT + F++ NL WL +A NWAKFTATASLGVI Sbjct: 354 KNTKDAV--RNSVCHTATVIANSFMHCGTTSDQFLRDNLEWLARATNWAKFTATASLGVI 411 Query: 375 HKGNLLEGKKVMAPYLP-GSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNIIVENSGT 433 HKG+ E ++MA YLP + S + +GG LY LGLI+A G D DYL N + S Sbjct: 412 HKGHEKEALQLMATYLPKDTSPGSAYQEGGGLYALGLIHANHGGDIIDYLLNQLKNASN- 470 Query: 434 SGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTG 493 D++ HG SLG+GLAAMG+A +VY+ LK LY D A +GEAA L +GL MLG+ Sbjct: 471 ------DIVRHGGSLGLGLAAMGTARQDVYDLLKTNLYQDDAVTGEAAGLALGLVMLGSK 524 Query: 494 KPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAF 553 +AI DM Y+QETQH I RGLAVG+AL+ YGR E AD LI + + +LR G + Sbjct: 525 NAQAIEDMVGYAQETQHEKILRGLAVGIALVMYGRMEEADALIESLCRDKDPILRRSGMY 584 Query: 554 TIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALGFVLLRDYTTVPRIVQLLSKSH 613 T+A+AY G+GNN A++RLLHVAVSD NDDVRRAAV +LGF+L R P +V LLS+S+ Sbjct: 585 TVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRAAVESLGFILFRTPEQCPSVVSLLSESY 644 Query: 614 NAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFVRQAAMIALSMILIQQTEKLNP 673 N HVR G A ALGI CAG G + AI++L+P+T DPV++VRQ A+IA ++I+IQQTE P Sbjct: 645 NPHVRYGAAMALGICCAGTGNKEAINLLEPMTNDPVNYVRQGALIASALIMIQQTEITCP 704 Query: 674 QVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGGRNVTIQLENADTGTLDTKSVVGL 733 +V + + VI +KH + +AKFGA +AQGI++AGG NVTI L+ + TG SVVG+ Sbjct: 705 KVNQFRQLYSKVINDKHDDVMAKFGAILAQGILDAGGHNVTISLQ-SRTGHTHMPSVVGV 763 Query: 734 VMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQAIPKFQMNCYAKEDAFSYPRMYEEASG 793 ++F+QFW+WFPL+HFLSL++TPT VIG+ D +PK Q K F+YP E Sbjct: 764 LVFTQFWFWFPLSHFLSLAYTPTCVIGLN-KDLKMPKVQYKSNCKPSTFAYPAPLEVPKE 822 Query: 794 KEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKEND 853 KE EKV+TAVLS TA+AK + K+ +K++ E + E ++ + Sbjct: 823 KEKEKVSTAVLSITAKAKKKEKEKEKKEEEKME-------------------VDEAEKKE 863 Query: 854 EEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVVVLRD-----R 908 E+ K + +DN R++P Q + ++ + R+ P + G+++L+D Sbjct: 864 EKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPETCRYQPFKPLS-IGGIIILKDTSEDIE 922 Query: 909 EPKEPVA 915 E EPVA Sbjct: 923 ELVEPVA 929 >5VHF-U nrPDB Length = 841 Score = 1181 bits (3054), Expect = 0.0, Method: Composition-based stats. Identities = 353/874 (40%), Positives = 507/874 (58%), Gaps = 93/874 (10%) Query: 96 QFVETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALG 155 ++VETI++K I+ Y ++ + E K ID +L I +M ++CL + K A+G Sbjct: 1 EYVETIIAKCIDHYTKQCVENADLPEG--EKKPIDQRLEGIVNKMFQRCLDDHKYKQAIG 58 Query: 156 IALEGYRLDIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLM 215 IALE RLD+ E K+ L+ + ++ Y L L ++ + N +FR+ +LR M Sbjct: 59 IALETRRLDVFE---KTILESNDVP---GMLAYSLKLCMSLMQNKQFRNKVLRVLVKIYM 112 Query: 216 NMPNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVT 275 N+ D++ + + ++ L+D + +KL +E++ ++ QI FDL SASQQ L ++ Sbjct: 113 NLEKPDFINVCQCLIFLDDPQAVSDILEKLVKEDNLLMAYQICFDLYESASQQFLSSVIQ 172 Query: 276 ELTAQGYDPA------------------------------------------------LL 287 L G A ++ Sbjct: 173 NLRTVGTPIASVPGSTNTGTVPGSEKDSDSMETEEKTSSAFVGKTPEASPEPKDQTLKMI 232 Query: 288 NILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANGFMHAGTTDNS 347 ILSG + + FL+ N N D+ +L +K ++ + S+ HTA +AN FMH GTT + Sbjct: 233 KILSGEMAIELHLQFLIRNNNTDLMILKNTKDAV--RNSVCHTATVIANSFMHCGTTSDQ 290 Query: 348 FIKANLPWLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYLP-GSRASSRFIKGGSLY 406 F++ NL WL +A NWAKFTATASLGVIHKG+ E ++MA YLP + S + +GG LY Sbjct: 291 FLRDNLEWLARATNWAKFTATASLGVIHKGHEKEALQLMATYLPKDTSPGSAYQEGGGLY 350 Query: 407 GLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEAL 466 LGLI+A G D DYL N + S D++ HG SLG+GLAAMG+A +VY+ L Sbjct: 351 ALGLIHANHGGDIIDYLLNQLKNASN-------DIVRHGGSLGLGLAAMGTARQDVYDLL 403 Query: 467 KEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINY 526 K LY D A +GEAA L +GL MLG+ +AI DM Y+QETQH I RGLAVG+AL+ Y Sbjct: 404 KTNLYQDDAVTGEAAGLALGLVMLGSKNAQAIEDMVGYAQETQHEKILRGLAVGIALVMY 463 Query: 527 GRQELADDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRA 586 GR E AD LI + + +LR G +T+A+AY G+GNN A++RLLHVAVSD NDDVRRA Sbjct: 464 GRMEEADALIESLCRDKDPILRRSGMYTVAMAYCGSGNNKAIRRLLHVAVSDVNDDVRRA 523 Query: 587 AVIALGFVLLRDYTTVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTK 646 AV +LGF+L R P +V LLS+S+N HVR G A ALGI CAG G + AI++L+P+T Sbjct: 524 AVESLGFILFRTPEQCPSVVSLLSESYNPHVRYGAAMALGICCAGTGNKEAINLLEPMTN 583 Query: 647 DPVDFVRQAAMIALSMILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIM 706 DPV++VRQ A+IA ++I+IQQTE P+V + + VI +KH + +AKFGA +AQGI+ Sbjct: 584 DPVNYVRQGALIASALIMIQQTEITCPKVNQFRQLYSKVINDKHDDVMAKFGAILAQGIL 643 Query: 707 NAGGRNVTIQLENADTGTLDTKSVVGLVMFSQFWYWFPLAHFLSLSFTPTTVIGIRGSDQ 766 +AGG NVTI L+ + TG SVVG+++F+QFW+WFPL+HFLSL++TPT VIG+ D Sbjct: 644 DAGGHNVTISLQ-SRTGHTHMPSVVGVLVFTQFWFWFPLSHFLSLAYTPTCVIGLN-KDL 701 Query: 767 AIPKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEE 826 +PK Q K F+YP E KE EKV+TAVLS TA+AK + K+ +K++ E Sbjct: 702 KMPKVQYKSNCKPSTFAYPAPLEVPKEKEKEKVSTAVLSITAKAKKKEKEKEKKEEEKME 761 Query: 827 EKKKEHEEKEKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIK 886 + E ++ +E+ K + +DN R++P Q + ++ + Sbjct: 762 -------------------VDEAEKKEEKEKKKEPEPNFQLLDNPARVMPAQLKVLTMPE 802 Query: 887 DDRFVPVRKFKGNNGVVVLRD-----REPKEPVA 915 R+ P + G+++L+D E EPVA Sbjct: 803 TCRYQPFKPLS-IGGIIILKDTSEDIEELVEPVA 835 >5T0J-f nrPDB Length = 749 Score = 319 bits (818), Expect = 3e-87, Method: Composition-based stats. Identities = 130/624 (20%), Positives = 234/624 (37%), Gaps = 88/624 (14%) Query: 165 IIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYLT 224 ++E L++D + LT + V + S++LR + + Sbjct: 49 LMEIEQVDMLEKDIDENAYAKVCLYLTSCVNYVPEPE-NSALLRCALGVFRKFSR--FPE 105 Query: 225 LNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAF---------DLVSSASQ-QLLEILV 274 ++ + LND L +F K D + Q+AF +L + + L ++ Sbjct: 106 ALRLALMLNDMELVEDIFTSCK---DVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEIM 162 Query: 275 TELTAQGYDPAL---LNILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTA 331 + + AL L+I+ D Y T L NN+ S S +D + + A Sbjct: 163 SNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNR------FGGSGSQVDS--ARMNLA 214 Query: 332 VSVANGFMHAGTTDNSFIKANLP-WLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYL 390 S NGF++A + + + WL K ++ +A ASLG+I ++ G + YL Sbjct: 215 SSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKYL 274 Query: 391 PGSRASSRFIKGGSLYGLGLIYAGFGRDTTD----YLKNIIVENSGTSGDEDVDVLLHGA 446 +S +IK G+L G++ +G R+ D L + ++ NS T + G+ Sbjct: 275 ---YSSEDYIKSGALLACGIVNSGV-RNECDPALALLSDYVLHNSNT--------MRLGS 322 Query: 447 SLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAA---LGMGLCMLGTGKPEAIHDMFT 503 G+GLA GS +V L V+ DS +S E A L G+ +G+ + + Sbjct: 323 IFGLGLAYAGSNREDVLTLLLPVM-GDSKSSMEVAGVTALACGMIAVGSCNGDVTSTILQ 381 Query: 504 YSQETQHGNI----TRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTIALAY 559 E + R L +GL L + G+ E + ++ + E + AY Sbjct: 382 TIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCAY 441 Query: 560 AGTGNNSAVKRLLHVAVSDSN-----------------------DDVRRAAVIALGFVLL 596 AG+GN V++LLH+ + D V LG L+ Sbjct: 442 AGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIALI 501 Query: 597 RDYTTVPRIVQLLSKSH-----NAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDF 651 + + L + H +R AL + + +D L + D Sbjct: 502 AMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADPE 561 Query: 652 VRQAAMIALSMILI-QQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAGG 710 V ++ A+ M+ +L + + + N F +AQG+ + G Sbjct: 562 VSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNN-------LFMVRLAQGLTHLGK 614 Query: 711 RNVTIQLENADTGTLDTKSVVGLV 734 +T+ ++D + +V GL+ Sbjct: 615 GTLTLCPYHSDRQLMSQVAVAGLL 638 >5LN3-Z nrPDB Length = 908 Score = 319 bits (818), Expect = 3e-87, Method: Composition-based stats. Identities = 146/745 (19%), Positives = 278/745 (37%), Gaps = 107/745 (14%) Query: 45 DIEALYDDDT-FSDREMAALIASKVYYNLGEYESAVKYALAAKDRFDIDEKSQFVETIVS 103 ++ +Y++ ++ AA I S + + +KY L ++V Sbjct: 105 KLKEIYENMAPGENKRFAADIISVLAMTMSGERECLKYRLVGSQEELASWGHEYVR---- 160 Query: 104 KSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRL 163 E +K++ E + + L ++ + ++ + + A + +E ++ Sbjct: 161 ----HLAGEVAKEWQ--ELDDAEKVQREPLLTLVKEIVPYNMAHNAEHEACDLLMEIEQV 214 Query: 164 DIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRKSFDFLMNMPNCDYL 223 D++E + + K+ Y LT + V + S++LR + + Sbjct: 215 DMLEKDI-------DENAYAKVCLY-LTSCVNYVPEPE-NSALLRCALGVFRKFSR--FP 263 Query: 224 TLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAF---------DLVSSASQ-QLLEIL 273 ++ + LND L +F K D + Q+AF +L + + L + Sbjct: 264 EALRLALMLNDMELVEDIFTSCK---DVVVQKQMAFMLGRHGVFLELSEDVEEYEDLTEI 320 Query: 274 VTELTAQGYDPAL---LNILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHT 330 ++ + AL L+I+ D Y T L NN+ S S +D + + Sbjct: 321 MSNVQLNSNFLALARELDIMEPKVPDDIYKTHLENNR------FGGSGSQVDS--ARMNL 372 Query: 331 AVSVANGFMHAGTTDNSFIKANLP-WLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPY 389 A S NGF++A + + + WL K ++ +A ASLG+I ++ G + Y Sbjct: 373 ASSFVNGFVNAAFGQDKLLTDDGNKWLYKNKDHGMLSAAASLGMILLWDVDGGLTQIDKY 432 Query: 390 LPGSRASSRFIKGGSLYGLGLIYAGFGRDTTD----YLKNIIVENSGTSGDEDVDVLLHG 445 L +S +IK G+L G++ +G R+ D L + ++ NS T + G Sbjct: 433 L---YSSEDYIKSGALLACGIVNSGV-RNECDPALALLSDYVLHNSNT--------MRLG 480 Query: 446 ASLGIGLAAMGSANIEVYEALKEVLYNDSATSGEAAA---LGMGLCMLGTGKPEAIHDMF 502 + G+GLA GS +V L V+ DS +S E A L G+ +G+ + + Sbjct: 481 SIFGLGLAYAGSNREDVLTLLLPVM-GDSKSSMEVAGVTALACGMIAVGSCNGDVTSTIL 539 Query: 503 TYSQETQHGNI----TRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTIALA 558 E + R L +GL L + G+ E + ++ + E + A Sbjct: 540 QTIMEKSETELKDTYARWLPLGLGLNHLGKGEAIEAILAALEVVSEPFRSFANTLVDVCA 599 Query: 559 YAGTGNNSAVKRLLHVAVSDSN-----------------------DDVRRAAVIALGFVL 595 YAG+GN V++LLH+ + D V LG L Sbjct: 600 YAGSGNVLKVQQLLHICSEHFDSKEKEEDKDKKEKKDKDKKEAPADMGAHQGVAVLGIAL 659 Query: 596 LRDYTTVPRIVQLLSKSH-----NAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVD 650 + + + L + H +R AL + + +D L + D Sbjct: 660 IAMGEEIGAEMALRTFGHLLRYGEPTLRRAVPLALALISVSNPRLNILDTLSKFSHDADP 719 Query: 651 FVRQAAMIALSMILI-QQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAG 709 V ++ A+ M+ +L + + + N F +AQG+ + G Sbjct: 720 EVSYNSIFAMGMVGSGTNNARLAAMLRQLAQYHAKDPNN-------LFMVRLAQGLTHLG 772 Query: 710 GRNVTIQLENADTGTLDTKSVVGLV 734 +T+ ++D + +V GL+ Sbjct: 773 KGTLTLCPYHSDRQLMSQVAVAGLL 797 >5WVI-Z nrPDB Length = 993 Score = 292 bits (748), Expect = 4e-79, Method: Composition-based stats. Identities = 70/272 (25%), Positives = 122/272 (44%), Gaps = 24/272 (8%) Query: 318 KSSLDGKFSLF----------HTAVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTA 367 KS LD S+F + A S NGF++ G ++ I N W+ K + +A Sbjct: 359 KSHLDNSKSVFSSAGLDSAQQNLASSFVNGFLNLGYCNDKLIVDNDNWVYKTKGDGMTSA 418 Query: 368 TASLGVIHKGNLLEGKKVMAPYLPGSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNII 427 AS+G I++ N L+G + + YL +K G+L G+G+ +G D ++ Sbjct: 419 VASIGSIYQWN-LDGLQQLDKYL---YVDEPEVKAGALLGIGISASGV-HDGEVEPALLL 473 Query: 428 VENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVYEALKEVLYNDS--ATSGEAAALGM 485 +++ T+ D + A LG+G+A GS N EV L + + + A+L + Sbjct: 474 LQDYVTNPDTKIS---SAAILGLGIAFAGSKNDEVLGLLLPIAASTDLPIETAAMASLAL 530 Query: 486 GLCMLGTGKPE---AIHDMFTYSQETQ-HGNITRGLAVGLALINYGRQELADDLITKMLA 541 +GT + +I D F + + R LA+ L ++ G+ E DD++ + A Sbjct: 531 AHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFLALALGILYMGQGEQVDDVLETISA 590 Query: 542 SDESLLRYGGAFTIALAYAGTGNNSAVKRLLH 573 + + + AY GTG+ ++ LLH Sbjct: 591 IEHPMTSAIEVLVGSCAYTGTGDVLLIQDLLH 622 Score = 35.8 bits (81), Expect = 0.089, Method: Composition-based stats. Identities = 79/388 (20%), Positives = 138/388 (35%), Gaps = 46/388 (11%) Query: 473 DSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLAVGLALINYGRQELA 532 DSA A++ G LG + I D + +T+ +T +A + I + Sbjct: 375 DSAQQNLASSFVNGFLNLGYCNDKLIVDNDNWVYKTKGDGMTSAVA-SIGSIYQWNLDGL 433 Query: 533 DDLITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDVRRAAVIALG 592 + K L DE ++ G I ++ +G + LL Sbjct: 434 QQ-LDKYLYVDEPEVKAGALLGIGISASGVHDGEVEPALL-------------------- 472 Query: 593 FVLLRDYTTVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAIDVLDPLTKDPVDFV 652 LL+DY T P + + LGIA AG + +L P+ + Sbjct: 473 --LLQDYVTNP----------DTKISSAAILGLGIAFAGSKNDEVLGLLLPIAASTDLPI 520 Query: 653 RQAAMIALSMILIQQTEKLNPQVADINKNFLSVITNKHQEGLAKFGACVAQGIMNAG-GR 711 AAM +L++ + I NFL + + +F A +A GI+ G G Sbjct: 521 ETAAMASLALAHVFVGTCNGDITTSIMDNFLERTAIELKTDWVRFLA-LALGILYMGQGE 579 Query: 712 NVTIQLENADTGTLDTKSVVGLVMFSQFWYW---FPLAHFLSLSFTPTTVIGIRGSDQAI 768 V LE S + +++ S + L L TP V G +D+ Sbjct: 580 QVDDVLETISAIEHPMTSAIEVLVGSCAYTGTGDVLLIQDLLHRLTPKNVKGEEDADEEE 639 Query: 769 PKFQMNCYAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKA---RAKKTKKEKGPNE 825 + D E + E ++ + A + +A+ T+K+ G + Sbjct: 640 TAEG-QTNSISDFLG--EQVNEPTKNEEAEIEVDEMEVDAEGEEVEVKAEITEKKNGESL 696 Query: 826 EEKKKEHEEKEKERETNKKGIKETKEND 853 E ++ + EEK K + ++K + K +D Sbjct: 697 EGEEIKSEEK-KGKSSDKDATTDGKNDD 723 Score = 34.3 bits (77), Expect = 0.28, Method: Composition-based stats. Identities = 20/134 (14%), Positives = 48/134 (35%), Gaps = 6/134 (4%) Query: 404 SLYGLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGIGLAAMGSANIEVY 463 ++ G+ LI G D K + + + G + + L +G+ ++ ++V+ Sbjct: 739 AVLGIALIALG-----EDIGKEMSLRHFGHLMHYGNEHIRRMVPLAMGIVSVSDPQMKVF 793 Query: 464 EALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLA-VGLA 522 + L ++ + MGLC GT + + + + Sbjct: 794 DTLTRFSHDADLEVSMNSIFAMGLCGAGTNNARLAQLLRQLASYYSREQDALFITRLAQG 853 Query: 523 LINYGRQELADDLI 536 L++ G+ + D+ Sbjct: 854 LLHLGKGTMTMDVF 867 Score = 33.1 bits (74), Expect = 0.52, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 32/85 (37%), Gaps = 4/85 (4%) Query: 442 LLHGASLGIGLAAMGSANIEVYEALKEVL--YNDSATSGEAAALGMGLCMLGTGKPEAIH 499 + + +GL G+ N + + L+++ Y+ + L GL LG K Sbjct: 807 VSMNSIFAMGLCGAGTNNARLAQLLRQLASYYSREQDALFITRLAQGLLHLG--KGTMTM 864 Query: 500 DMFTYSQETQHGNITRGLAVGLALI 524 D+F + + L + L+ Sbjct: 865 DVFNDAHVLNKVTLASILTTAVGLV 889 Score = 32.0 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 28/68 (41%), Gaps = 1/68 (1%) Query: 580 NDDVRRAAVIALGFVLLRDYT-TVPRIVQLLSKSHNAHVRCGTAFALGIACAGKGLQSAI 638 N+ +RR +A+G V + D V + S + V + FA+G+ AG Sbjct: 769 NEHIRRMVPLAMGIVSVSDPQMKVFDTLTRFSHDADLEVSMNSIFAMGLCGAGTNNARLA 828 Query: 639 DVLDPLTK 646 +L L Sbjct: 829 QLLRQLAS 836 >2NBW-A nrPDB Length = 131 Score = 148 bits (373), Expect = 1e-35, Method: Composition-based stats. Identities = 32/128 (25%), Positives = 55/128 (42%), Gaps = 6/128 (4%) Query: 442 LLHGASLGIGLAAMGSANIEVYEALKEVLYNDS--ATSGEAAALGMGLCMLGTGKPE--- 496 + A LG+G+A GS N EV L + + + A+L + +GT + Sbjct: 4 ISSAAILGLGIAFAGSKNDEVLGLLLPIAASTDLPIETAAMASLALAHVFVGTCNGDITT 63 Query: 497 AIHDMFTYSQETQ-HGNITRGLAVGLALINYGRQELADDLITKMLASDESLLRYGGAFTI 555 +I D F + + R LA+ L ++ G+ E DD++ + A + + Sbjct: 64 SIMDNFLERTAIELKTDWVRFLALALGILYMGQGEQVDDVLETISAIEHPMTSAIEVLVG 123 Query: 556 ALAYAGTG 563 + AY GTG Sbjct: 124 SCAYTGTG 131 >6FEC-u nrPDB Length = 636 Score = 37.8 bits (86), Expect = 0.022, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 42/113 (37%), Gaps = 12/113 (10%) Query: 777 AKE-DAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEK 835 AK D + R EE KE EK+ + + R + +E ++ + Sbjct: 389 AKPVDTAAREREVEERLQKEQEKLQRQLDEPKLERRPRERHPSWRSEETQERERSRTGSE 448 Query: 836 EKERETNKKGIKETKEND-EEFYKNK----------YSSKPYKVDNMTRILPQ 877 + T+ + + + E+ +N+ +SKP K D +++P Sbjct: 449 SSQTGTSTTSSRNARRRESEKSLENETLNKEEDCHSPTSKPPKPDQPLKVMPA 501 >3PDK-A nrPDB Length = 469 Score = 35.1 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 47/240 (19%), Positives = 76/240 (31%), Gaps = 29/240 (12%) Query: 217 MPNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTE 276 +P L +V LQ K+ EE+ GL IA D A+ L L + Sbjct: 159 LPRPTGTNLGQVSDYFEGGQKYLQYIKQTVEEDFSGL--HIALDCAHGATSSLAPYLFAD 216 Query: 277 L----TAQGYDPALLNILSGLPTCDYY-NTFLLNNKNIDIGL-LNKSKSSLDGKFSLFHT 330 L + G P +NI G+ + L+ K DIGL + L + Sbjct: 217 LEADISTMGTSPNGMNINDGVGSTHPEVLAELVKEKGADIGLAFDGDGDRLIAVDEKGNI 276 Query: 331 AVSVANGFMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVIHKGNLLEGKKVMAPYL 390 F+ A + G+ ++ + S +K G + Sbjct: 277 VDGDQIMFICAKYMKET---------GQLKHNTVVSTVMSNLGFYKALEANGITSDKTAV 327 Query: 391 PGSRASSRFIKGGSLYGLGLIYAGFGRDTTDYLKNIIVENSGTSGDEDVDVLLHGASLGI 450 +GG Y LG +G II+ + T+GD + L + + Sbjct: 328 GDRYVMEEMKRGG--YNLGGEQSGH----------IILLDYITTGDGMLSALQLVNIMKM 375 >2WN7-A nrPDB Length = 463 Score = 34.7 bits (78), Expect = 0.18, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 49/137 (35%), Gaps = 13/137 (9%) Query: 783 SYPRMYEEASG--KEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERE 840 +Y E K+ EK A A+ +K ++ + E KK+ E K + Sbjct: 48 TYKAPIERPEDFLKDKEK---AKEWERKEAERIEQKLERSEKEALESYKKDSVEISKYSQ 104 Query: 841 TNKKGIK---ETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFK 897 T E ++E+ + + + K+D + Y + F V + + Sbjct: 105 TRNYFYDYQIEANSREKEYKELRNAISKNKIDKPMYVY-----YFESPEKFAFNKVIRTE 159 Query: 898 GNNGVVVLRDREPKEPV 914 N + + + E KE + Sbjct: 160 NQNEISLEKFNEFKETI 176 >6NOD-A nrPDB Length = 356 Score = 33.9 bits (76), Expect = 0.30, Method: Composition-based stats. Identities = 23/160 (14%), Positives = 61/160 (38%), Gaps = 19/160 (11%) Query: 127 DIIDPKLTSIFERMIEKCLKASELKLALGIALEGYRLDIIESALKSKLDQDSTSENVKII 186 + + K+ S +I +C+K + A+E ++ + + L+ +T + + Sbjct: 125 EPLQIKILSQIRHVIHRCMKDQNGNHVVQKAIEKVSPQYVQFIVDTLLESSNTIYEMSVD 184 Query: 187 NYLLTL---AITTVTNSKFRSSI--LRKSFDFLMNMPNCDYLTLNKVVVNLNDAGLALQL 241 Y + + + S+ + I + K FD + N +Y+ + Sbjct: 185 PYGCRVVQRCLEHCSPSQTKPVIGQIHKRFDEIANNQYGNYV--------------VQHV 230 Query: 242 FKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQG 281 + EE+ + +++ +L A+ + ++ + QG Sbjct: 231 IEHGSEEDRMVIVTRVSNNLFEFATHKYSSNVIEKCLEQG 270 >3ZYY-X nrPDB Length = 631 Score = 33.1 bits (74), Expect = 0.55, Method: Composition-based stats. Identities = 43/220 (19%), Positives = 76/220 (34%), Gaps = 30/220 (13%) Query: 218 PNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTEL 277 N D + V L QL K+ E E ++A +A + ++ + LEI + Sbjct: 256 ENPDGAEKLRKAVLSTINELIFQLCKEHGVEKKEIMAAVVAGN--TTMTHLFLEIDPRYI 313 Query: 278 TAQGYDPALLNILSGLPTCDYYNTFLLNNKNIDIGLLNKSKSSLDGKFSLFHTAVSVANG 337 + Y PA L I P + N + ++ S + G + +AN Sbjct: 314 RLEPYTPAALFI----PPVPATEAKIEMNPKGFVYIMPNVASYVGGDITSGVLYTGLANS 369 Query: 338 -----FMHAGTTDNSFIKANLPWLGKAQNWAKFTATASLGVIHKGN-LLEGKKVMAPYLP 391 F+ GT N + ++W T S G +G+ + G + M + Sbjct: 370 DEITLFIDIGT--------NGEMVLGNKDW-LVTCACSAGPAFEGSGIKHGMRAMQGAIE 420 Query: 392 GSRASSR-----FIKGGSLYGLGLIYAGFGRDTTDYLKNI 426 S + G + +G+ +G D L N+ Sbjct: 421 RVSISEAGLKVKYQTVGGIPPVGICGSGL----IDLLANL 456 >5N3U-A nrPDB Length = 276 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 39/155 (25%), Positives = 59/155 (38%), Gaps = 32/155 (20%) Query: 531 LADDLITKMLASDE-------SLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSNDDV 583 D LI + + L R A A GN AV L++ + + V Sbjct: 51 AVDALIAALEDEADRTELGGYPLRRNA-----ARALGKLGNRKAVPGLIN-CLECPDFYV 104 Query: 584 RRAAVIALGFVLLRDYTTVPRIVQLLSK--------SHNAHV--RCGTAF-ALGIACAGK 632 R AA +L +L+D T P +++LL + H+ ALG Sbjct: 105 REAAAQSLE--MLKDKTAAPALIKLLDGGVAQAVQVTGRPHLVQPYEAVLEALG----AI 158 Query: 633 GLQSAIDVLDPLTKDPVDFVRQAAMIALSMILIQQ 667 G AI ++ P + PV V+ AA A +M + Q Sbjct: 159 GATDAIPLIQPFLEHPVSRVQCAA--ARAMYQLTQ 191 >3JCR-F nrPDB Length = 820 Score = 32.0 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 45/106 (42%), Gaps = 5/106 (4%) Query: 811 KARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKENDEEFYKNKYS--SKPYKV 868 + ++ ++E+ + +KKE +++ +R ++K + E + D ++ YS +K K+ Sbjct: 327 RRTLEEKEQEEARLRKLRKKEAKQRWDDRHWSQKKLDEMTDRDWRIFREDYSITTKGGKI 386 Query: 869 DNMTRILPQQS---RYISFIKDDRFVPVRKFKGNNGVVVLRDREPK 911 N R S + I + + + L++R+ Sbjct: 387 PNPIRSWKDSSLPPHILEVIDKCGYKEPTPIQRQAIPIGLQNRDII 432 >3IZY-P nrPDB Length = 537 Score = 32.0 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 46/132 (34%), Gaps = 14/132 (10%) Query: 759 IGIRGSDQAIPKFQMNCYAKEDAFSYPR-MYEEASGKEVEKVATAVLSTTARAKARA--- 814 I + G A + + + +YP +++ +L + +AR Sbjct: 210 ILVAGKSWAKVRLMFDENGRAVNEAYPSMPVGIIGWRDLPSAGDEILEVESEPRAREVVD 269 Query: 815 -------KKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKETKE---NDEEFYKNKYSSK 864 ++ KE EEK+KEH+E ++ + + E + + Sbjct: 270 WRKYEQEQEKNKEDLKLIEEKRKEHQEAHRKDREKYGTVHWKERSYIKYREKRQQQPLKP 329 Query: 865 PYKVDNMTRILP 876 K++ + +LP Sbjct: 330 KEKLERDSNVLP 341 >1YEY-A nrPDB Length = 444 Score = 31.2 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 15/100 (15%), Positives = 38/100 (38%), Gaps = 3/100 (3%) Query: 456 GSANIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITR 515 G+ ++ Y + + + + AAL + L K I D+ +++ + + R Sbjct: 46 GAEDLAGYGLVFTIGRGNDVQTAAVAALAEHVVGLSVDK--VIADLGAFARRLTNDSQLR 103 Query: 516 GLAVGLALINYGRQELAD-DLITKMLASDESLLRYGGAFT 554 L +++ + + A+++ L R+ T Sbjct: 104 WLGPEKGVMHMAIGAVINAAWDLAARAANKPLWRFIAELT 143 >4OER-A nrPDB Length = 500 Score = 31.2 bits (69), Expect = 2.4, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 32/68 (47%), Gaps = 4/68 (5%) Query: 232 LNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQLLEILVTELTAQGYDPALLNILS 291 L++AG + ++E++ + L+ ++ F + S+ + EI+ +L G D L+ Sbjct: 317 LDEAGWTAKASGDIREKDGQPLAIELCFIGTDAISKSMAEIVQADLRKVGIDVK----LT 372 Query: 292 GLPTCDYY 299 G Y Sbjct: 373 GEEESSIY 380 >3RQF-A nrPDB Length = 214 Score = 30.8 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 25/120 (20%), Positives = 46/120 (38%), Gaps = 4/120 (3%) Query: 784 YPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKEKERETNK 843 Y MY + E ++ A T RA A K K+ G ++ K E+K E + Sbjct: 25 YAVMYPVFNELERVNLSAA---QTLRA-AFIKAEKENPGLTQDIIMKILEKKSVEVNFTE 80 Query: 844 KGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQSRYISFIKDDRFVPVRKFKGNNGVV 903 ++ ++ EE+ + + ++ R L Q I +DR ++ K + Sbjct: 81 SLLRMAADDVEEYMIERPEPEFQDLNEKARALKQILSKIPDEINDRVRFLQTIKDIASAI 140 >2QAG-C nrPDB Length = 418 Score = 30.4 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 20/130 (15%), Positives = 41/130 (31%), Gaps = 7/130 (5%) Query: 762 RGSDQAIPKFQMNC--YAKEDAFSYPRMYEEASGKEVEKVATAVLSTTARAKARAKKTKK 819 + + N K + + E VA + K K Sbjct: 289 NYRSRKLAAVTYNGVDNNKNKGQLTKSPLAQMEEERREHVAKMKKMEMEMEQVFEMKVK- 347 Query: 820 EKGPNEEEKKKEHEEKEKERETNKKGIKETKENDEEFYKNKYSSKPYKVDNMTRILPQQS 879 ++ K E ++ E KK + E + + E + ++ + + RIL QQ+ Sbjct: 348 ---EKVQKLKDSEAELQRRHEQMKKNL-EAQHKELEEKRRQFEDEKANWEAQQRILEQQN 403 Query: 880 RYISFIKDDR 889 + K+ + Sbjct: 404 SSRTLEKNKK 413 >4GFQ-A nrPDB Length = 209 Score = 30.4 bits (67), Expect = 4.2, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 32/81 (39%), Gaps = 7/81 (8%) Query: 783 SYPRMYEEAS-------GKEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEK 835 ++P + EE K E+ AV + KK +K E++ + E+ Sbjct: 125 AFPALTEERRRDLVKVVKKYAEEAKVAVRNVRRDGNDDLKKLEKAGEITEDDLRGYTEDI 184 Query: 836 EKERETNKKGIKETKENDEEF 856 +KE + + E +N E+ Sbjct: 185 QKETDKYIAKVDEIAKNKEKE 205 >2H8F-A nrPDB Length = 143 Score = 30.4 bits (67), Expect = 4.2, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 33/63 (52%), Gaps = 5/63 (7%) Query: 145 LKASELKLALGIALEGYRLDIIESALKSKLDQDST-----SENVKIINYLLTLAITTVTN 199 +KA K+ GIAL ++D +++ L +Q + N KI+N+ + + I+T+ Sbjct: 57 IKAHGKKVMGGIALAVSKIDDLKTGLMELSEQHAYKLRVDPANFKILNHCILVVISTMFP 116 Query: 200 SKF 202 +F Sbjct: 117 KEF 119 >3JAX-A nrPDB Length = 974 Score = 30.1 bits (66), Expect = 5.2, Method: Composition-based stats. Identities = 12/80 (15%), Positives = 35/80 (43%), Gaps = 1/80 (1%) Query: 782 FSYPRMYEEASGKEVEKVATAVLSTTAR-AKARAKKTKKEKGPNEEEKKKEHEEKEKERE 840 F+ + +++ +E E + T + A +++ +KE +E + + + + Sbjct: 844 FTKVKPLLQSAEREKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQ 903 Query: 841 TNKKGIKETKENDEEFYKNK 860 + + + +E ++ KNK Sbjct: 904 AEQDNLADAEERCDQLIKNK 923 >2OWY-A nrPDB Length = 306 Score = 29.7 bits (65), Expect = 6.2, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 28/64 (43%) Query: 459 NIEVYEALKEVLYNDSATSGEAAALGMGLCMLGTGKPEAIHDMFTYSQETQHGNITRGLA 518 E+ + L + +++ A A +GL ++ + + D+ + +E R L+ Sbjct: 108 KDEIVQTLLPRAFIRRSSTFAAIAPSLGLILVDSASAKKAEDLLSTLREALGSLPVRPLS 167 Query: 519 VGLA 522 V +A Sbjct: 168 VKVA 171 >5W5C-E nrPDB Length = 83 Score = 29.7 bits (65), Expect = 6.3, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 30/54 (55%), Gaps = 3/54 (5%) Query: 810 AKARAKKTKKEKGPNEEEKKKEHEEKEKERETNKKGIKET---KENDEEFYKNK 860 A + ++ ++ EEE+K ++ + E ERE ++GI++ K+ +E + + Sbjct: 30 AAKKEEERQEALRQAEEERKAKYAKMEAEREVMRQGIRDKYGIKKKEEREAEAQ 83 >5OQL-K nrPDB Length = 938 Score = 29.7 bits (65), Expect = 6.6, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 31/82 (37%), Gaps = 2/82 (2%) Query: 769 PKFQMNCYAKEDAFSYPRMYEEASGK--EVEKVATAVLSTTARAKARAKKTKKEKGPNEE 826 PK + ++K D + + G+ E++ A+ A+AKA + + +G Sbjct: 689 PKVEAGAWSKPDDEGSSKPRKAPKGRPEEIDVTDLALAGKPAKAKANGQAKSQVQGKAHA 748 Query: 827 EKKKEHEEKEKERETNKKGIKE 848 + ++ G +E Sbjct: 749 SNGQSSSSQKASTSVAITGAEE 770 >5YFP-B nrPDB Length = 971 Score = 29.3 bits (64), Expect = 9.0, Method: Composition-based stats. Identities = 49/268 (18%), Positives = 89/268 (33%), Gaps = 56/268 (20%) Query: 90 DIDEKSQFVETIVSKSIEMYVQEASKQYTKDEQFYTKDIIDPKLTSIFERMIEKCLKASE 149 DI ++S ++ +V K+ YV+ K+ +D E+ EK S Sbjct: 139 DIQDQSIHLKQLVGKNFTKYVK-------------IKNKLDQIYKEFDEKTNEKNQCDSP 185 Query: 150 LKLALGIALEGYRLDIIESALKSKLDQDSTSENVKIINYLLTLAITTVTNSKFRSSILRK 209 + + + ++D + KL KI+NY T KF Sbjct: 186 KENQINVESLNKKVDEVIRTTTFKLKP-LMDNYQKILNYQAT--------KKFIE----- 231 Query: 210 SFDFLMNMPNCDYLTLNKVVVNLNDAGLALQLFKKLKEENDEGLSAQIAFDLVSSASQQL 269 F N+P +L + + N + F + E +GL+ + F+ S ASQ L Sbjct: 232 LNKFYFNLPK----SLKRCLTNND--------FNEFIIEYSKGLTLRRRFNQSSDASQSL 279 Query: 270 ----LEILVTELTAQGYDPALLNILSGLPTCD-------------YYNTFLLNNKNIDIG 312 + + L D ++++ D +NN + Sbjct: 280 VIKRIWTQIENLLVTYKDLIWNSLINSNFNIDQPQETILSLFSKLLNLENFINNNQRESE 339 Query: 313 LLNKSKSSLDGKFSLFHTAVSVANGFMH 340 NK+ +S + + NGF + Sbjct: 340 SGNKNTTSSSNENPILRWMSIKMNGFQN 367 >1WCM-D nrPDB Length = 177 Score = 29.3 bits (64), Expect = 9.0, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 34/92 (36%), Gaps = 2/92 (2%) Query: 523 LINYGRQELADDL--ITKMLASDESLLRYGGAFTIALAYAGTGNNSAVKRLLHVAVSDSN 580 + + G +E L L E+L+ AF + ++ LL +N Sbjct: 35 INHQGEEEELIALNLSEARLVIKEALVERRRAFKRSQKKTREKELESIDVLLEQTTGGNN 94 Query: 581 DDVRRAAVIALGFVLLRDYTTVPRIVQLLSKS 612 D++ F RD TV ++QLL + Sbjct: 95 KDLKNTMQYLTNFSRFRDQETVGAVIQLLKST 126 >4RM9-A nrPDB Length = 587 Score = 29.3 bits (64), Expect = 9.3, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 40/103 (38%), Gaps = 11/103 (10%) Query: 778 KEDAFSYPRMYEEASG-KEVEKVATAVLSTTARAKARAKKTKKEKGPNEEEKKKEHEEKE 836 K D +M +A K +++ L T K R + ++EK EK++ + Sbjct: 297 KPDTIEVQQMKAQAREEKHQKQLERQQLETE---KKRRETVEREKEQMMREKEELMLRLQ 353 Query: 837 KERETNKKGIKETKEN-------DEEFYKNKYSSKPYKVDNMT 872 E KK +E E +EE + + ++ + D M Sbjct: 354 DYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMA 396 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.131 0.341 Lambda K H 0.267 0.0399 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 32,352,356 Number of Sequences: 36641 Number of extensions: 1285760 Number of successful extensions: 6260 Number of sequences better than 10.0: 82 Number of HSP's better than 10.0 without gapping: 75 Number of HSP's successfully gapped in prelim test: 90 Number of HSP's that attempted gapping in prelim test: 5159 Number of HSP's gapped (non-prelim): 521 length of query: 945 length of database: 10,336,785 effective HSP length: 106 effective length of query: 839 effective length of database: 6,452,839 effective search space: 5413931921 effective search space used: 5413931921 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 64 (29.3 bits)