BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P32523 (503 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5LJ5-t nrPDB 1042 0.0 4ZB4-A nrPDB 757 0.0 5Z56-q nrPDB 102 3e-22 3JB9-S nrPDB 101 9e-22 5M88-A nrPDB 86 3e-17 1Y80-A nrPDB 33 0.28 4LG8-A nrPDB 32 0.56 5OPT-p nrPDB 31 0.96 4XI1-A nrPDB 31 1.2 5MRF-DD nrPDB 31 1.2 4V8M-A7 nrPDB 31 1.4 2C2L-A nrPDB 30 2.4 2F42-A nrPDB 30 2.9 4WZ3-B nrPDB 30 2.9 5L75-G nrPDB 29 5.2 2C2V-S nrPDB 29 5.3 1WGM-A nrPDB 28 6.8 2JLW-A nrPDB 28 7.3 2WZQ-A nrPDB 28 8.5 >5LJ5-t nrPDB Length = 503 Score = 1042 bits (2695), Expect = 0.0, Method: Compositional matrix adjust. Identities = 503/503 (100%), Positives = 503/503 (100%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA 60 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA Sbjct: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA 60 Query: 61 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK 120 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK Sbjct: 61 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK 120 Query: 121 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNL 180 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNL Sbjct: 121 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNL 180 Query: 181 ELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPR 240 ELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPR Sbjct: 181 ELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPR 240 Query: 241 TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTE 300 TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTE Sbjct: 241 TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTE 300 Query: 301 YFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLS 360 YFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLS Sbjct: 301 YFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLS 360 Query: 361 SPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFK 420 SPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFK Sbjct: 361 SPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFK 420 Query: 421 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVV 480 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVV Sbjct: 421 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVV 480 Query: 481 CGDGGIAAILKTNDSFNIVALTP 503 CGDGGIAAILKTNDSFNIVALTP Sbjct: 481 CGDGGIAAILKTNDSFNIVALTP 503 >4ZB4-A nrPDB Length = 360 Score = 757 bits (1954), Expect = 0.0, Method: Compositional matrix adjust. Identities = 360/360 (100%), Positives = 360/360 (100%) Query: 144 AVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKS 203 AVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKS Sbjct: 1 AVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKS 60 Query: 204 MYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPG 263 MYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPG Sbjct: 61 MYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPG 120 Query: 264 NQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYI 323 NQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYI Sbjct: 121 NQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYI 180 Query: 324 VHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFA 383 VHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFA Sbjct: 181 VHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFA 240 Query: 384 DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESN 443 DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESN Sbjct: 241 DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESN 300 Query: 444 SLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP 503 SLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP Sbjct: 301 SLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP 360 >5Z56-q nrPDB Length = 504 Score = 102 bits (255), Expect = 3e-22, Method: Compositional matrix adjust. Identities = 52/129 (40%), Positives = 81/129 (62%), Gaps = 8/129 (6%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA 60 ++C+IS +VP P +SP S ++E+ L+E+Y+ + G DPI N+PLS E++++I Sbjct: 3 LICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDI---KVAH 59 Query: 61 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK 120 + SAT SIP +L +LQ+EWDA+ML +F LR L + ++LS +Y+ DAA Sbjct: 60 PIRPKPPSAT-----SIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAAC 114 Query: 121 LVAAQLLME 129 V A+L E Sbjct: 115 RVIARLTKE 123 Score = 32.0 bits (71), Expect = 0.73, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 3/68 (4%) Query: 338 LHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTV 397 H D L+ + D + +++L ++ FP I + F++NGY++ D + Sbjct: 358 FHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FP-GHSGPITSIAFSENGYYLATAADDSS 415 Query: 398 V-CFDLRK 404 V +DLRK Sbjct: 416 VKLWDLRK 423 >3JB9-S nrPDB Length = 488 Score = 101 bits (251), Expect = 9e-22, Method: Compositional matrix adjust. Identities = 133/510 (26%), Positives = 215/510 (42%), Gaps = 111/510 (21%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEI-VPSAQQ 59 M C+ISG+ P+ PV+S S ++EK L+EQ +++T DP+T + ++E++V + VP + Sbjct: 1 MFCSISGETPKEPVISRVSGNVYEKRLIEQVIRETSKDPVTQQECTLEDLVPVKVPDFVR 60 Query: 60 ASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMY----- 114 +T S+P LL+ Q EWD++ LE F+LR L ++LST +Y Sbjct: 61 PRPPSAT---------SLPALLSLFQEEWDSVALEQFELRRNLTETKQELSTALYSLDAA 111 Query: 115 ---------ERDAAKLVAAQLL---------------MEKNEDSKDLPKSSQQAVAITRE 150 ERD A+ A+ +E E L S + V T + Sbjct: 112 LRVISRLTKERDEAREALAKFSDNIGTVSSKTIEVQEVEMGESDDQLKTSLRSTVEKTFQ 171 Query: 151 EFLQGLLQSSRDFVARGKLKAPKWPILKNL-ELLQAQNYS--RNIKT------FPYKELN 201 E L S R R KL+ PKW + +LLQA + N++T FP E N Sbjct: 172 E-----LSSKRK---RTKLQ-PKWATDDAVSQLLQATPSTILENLETESTTSFFPSPE-N 221 Query: 202 KS----MYYDKWVCM--------CRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAII 249 S ++ D+ +C+ E AL L SK + T + + E P + Sbjct: 222 SSFVLCLHKDELLCLDIQSNSTLKIFEGSALACCWLTSSKI--AVATADAISIFEFP-VS 278 Query: 250 SRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRG 309 S G + + P + I I D K N ++ H + EY + A N Sbjct: 279 SSGLQS---VGEPTSSIPI-DEKVN---------------FLQAHP--SGEYLLAASNEK 317 Query: 310 TIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRF 369 F V++ +S +H D L +G L + SS ++ + Sbjct: 318 CYIFSLKSQ-----VYNITVAQHITSLAVHPDGNLFVAGLENGELRFFETSSGNELTKFG 372 Query: 370 PVDEEAKIKEVKFADNGYWMVVEC--DQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYD 427 P + +K ++F +NGYW+VV D + +DLRK P T K V+ D Sbjct: 373 P--HSSPVKTLQFGENGYWLVVTTNDDSDIFIWDLRKSELVQKIPLQT----KVAAVSLD 426 Query: 428 IDDSGKNMIAYSNESNSLTIYKFDKKTKNW 457 I + + S++ +L ++ + K +K+W Sbjct: 427 I----TSQLLVSSDGETLYVHIYVKSSKSW 452 >5M88-A nrPDB Length = 136 Score = 86.3 bits (212), Expect = 3e-17, Method: Composition-based stats. Identities = 50/140 (35%), Positives = 84/140 (60%), Gaps = 8/140 (5%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIVEIVPSAQQ 59 MLCA+SG++P PV+S K+ +FEK L+ +Y+++ N +P T E L E +++P Sbjct: 1 MLCALSGEIPEEPVVSKKTGVLFEKRLILKYLEEHNNIEPGTTEELDPE--TDLLPIKTS 58 Query: 60 ASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAA 119 + + T SIP+LL + Q+EWDA++LE + R L + ++L+T +Y+ DAA Sbjct: 59 RVVRPRPPNFT-----SIPSLLKAFQDEWDALVLETYTTREQLARVREELATALYQHDAA 113 Query: 120 KLVAAQLLMEKNEDSKDLPK 139 V A+L E++E + L + Sbjct: 114 VRVIARLTRERDEAREALAR 133 >1Y80-A nrPDB Length = 210 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 9/60 (15%) Query: 410 AYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIY---------KFDKKTKNWTKD 460 A+ ++ + GTV D+ D GKN++A ES T+Y KF + K + D Sbjct: 82 AFDMPSVGKIVLGTVKGDLHDIGKNLVAMMLESGGFTVYNLGVDIEPGKFVEAVKKYQPD 141 >4LG8-A nrPDB Length = 354 Score = 32.0 bits (71), Expect = 0.56, Method: Compositional matrix adjust. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 3/68 (4%) Query: 338 LHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTV 397 H D L+ + D + +++L ++ FP I + F++NGY++ D + Sbjct: 208 FHPDGLIFGTGTMDSQIKIWDLKERTNVAN-FP-GHSGPITSIAFSENGYYLATAADDSS 265 Query: 398 V-CFDLRK 404 V +DLRK Sbjct: 266 VKLWDLRK 273 >5OPT-p nrPDB Length = 318 Score = 31.2 bits (69), Expect = 0.96, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query: 341 DSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCF 400 D L A DG+ +++L+ + S + A I ++ F+ N YWM ++ + F Sbjct: 207 DGSLCASSDKDGVARLWDLTKGEALSE---MAAGAPINQICFSPNRYWMCAATEKGIRIF 263 Query: 401 DLR-KDV 406 DL KDV Sbjct: 264 DLENKDV 270 >4XI1-A nrPDB Length = 101 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 31/51 (60%), Gaps = 1/51 (1%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIV 51 LC IS + + PV++ + + ++++ L ++ TGN T + LSI+++V Sbjct: 29 FLCPISKTLIKTPVITAQGK-VYDQEALSNFLIATGNKDETGKKLSIDDVV 78 >5MRF-DD nrPDB Length = 486 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 20/28 (71%) Query: 42 NEPLSIEEIVEIVPSAQQASLTESTNSA 69 NEPLSI+E+ + +P Q + L ES N+A Sbjct: 260 NEPLSIDELKQGLPEIQDSQLLESLNNA 287 >4V8M-A7 nrPDB Length = 318 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 33/67 (49%), Gaps = 4/67 (5%) Query: 341 DSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCF 400 D L A DG+ +++L+ + S + A I ++ F+ N YWM ++ + F Sbjct: 207 DGSLCASSDKDGVARLWDLTKGEALSE---MAAGAPINQICFSPNRYWMCAATEKGIRIF 263 Query: 401 DLR-KDV 406 DL KD+ Sbjct: 264 DLENKDI 270 >2C2L-A nrPDB Length = 281 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 34/52 (65%), Gaps = 3/52 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIV 51 LC IS ++ R P ++P T +++ +E++++ G+ +P+T PL+ E+++ Sbjct: 209 LCGKISFELMREPCITPSGIT-YDRKDIEEHLQRVGHFNPVTRSPLTQEQLI 259 >2F42-A nrPDB Length = 179 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 34/52 (65%), Gaps = 3/52 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIV 51 LC IS ++ R P ++P T +++ +E++++ G+ DP+T PL+ ++++ Sbjct: 107 LCGKISFELMREPCITPSGIT-YDRKDIEEHLQRVGHFDPVTRSPLTQDQLI 157 >4WZ3-B nrPDB Length = 215 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 31/51 (60%), Gaps = 1/51 (1%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIV 51 LC IS + + PV++ + + ++++ L ++ TGN T + LSI+++V Sbjct: 130 FLCPISKTLIKTPVITAQGK-VYDQEALSNFLIATGNKDETGKKLSIDDVV 179 >5L75-G nrPDB Length = 360 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 20/58 (34%), Positives = 25/58 (43%), Gaps = 10/58 (17%) Query: 449 KFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTN---DSFNIVALTP 503 KFD + K W Q D +D TD V G ++ KTN D +VAL P Sbjct: 196 KFDSENKVWRLS-------QVDESDLTDPKQVTGSQMVSGTWKTNLTPDKLGVVALDP 246 >2C2V-S nrPDB Length = 78 Score = 28.9 bits (63), Expect = 5.3, Method: Compositional matrix adjust. Identities = 15/52 (28%), Positives = 34/52 (65%), Gaps = 3/52 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIV 51 LC IS ++ R P ++P T +++ +E++++ G+ +P+T PL+ E+++ Sbjct: 6 LCGKISFELMREPCITPSGIT-YDRKDIEEHLQRVGHFNPVTRSPLTQEQLI 56 >1WGM-A nrPDB Length = 98 Score = 28.5 bits (62), Expect = 6.8, Method: Compositional matrix adjust. Identities = 11/38 (28%), Positives = 22/38 (57%) Query: 13 PVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEI 50 PV+ P SR ++S + +++ DP PL++++I Sbjct: 35 PVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQI 72 >2JLW-A nrPDB Length = 451 Score = 28.5 bits (62), Expect = 7.3, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query: 305 ADNRGTIGFQSYEDDSQYIVHS--AKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSP 362 A RG IG ++D QY+ K+D +++ K LL +Y+P+GI+ L P Sbjct: 288 AQRRGRIGRNPAQEDDQYVFSGDPLKNDEDHAHWTEAK-MLLDNIYTPEGIIP--TLFGP 344 Query: 363 DQASSRFPVDEEAKIK 378 ++ ++ +D E +++ Sbjct: 345 EREKTQ-AIDGEFRLR 359 >2WZQ-A nrPDB Length = 619 Score = 28.1 bits (61), Expect = 8.5, Method: Compositional matrix adjust. Identities = 21/76 (27%), Positives = 40/76 (52%), Gaps = 6/76 (7%) Query: 305 ADNRGTIGFQSYEDDSQYIVHS--AKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSP 362 A RG IG ++D QY+ K+D +++ K LL +Y+P+GI+ L P Sbjct: 456 AQRRGRIGRNPAQEDDQYVFSGDPLKNDEDHAHWTEAK-MLLDNIYTPEGIIP--TLFGP 512 Query: 363 DQASSRFPVDEEAKIK 378 ++ ++ +D E +++ Sbjct: 513 EREKTQ-AIDGEFRLR 527 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5LJ5-t nrPDB 858 0.0 4ZB4-A nrPDB 659 0.0 3JB9-S nrPDB 504 e-143 5Z56-q nrPDB 248 3e-66 5M88-A nrPDB 191 5e-49 Sequences not found previously or not previously below threshold: 5M89-A nrPDB 90 2e-18 4LG8-A nrPDB 68 1e-11 5OPT-p nrPDB 63 2e-10 4V8M-A7 nrPDB 56 3e-08 3DM0-A nrPDB 49 4e-06 6G51-g nrPDB 48 9e-06 4V6W-Ag nrPDB 45 6e-05 5WLC-LO nrPDB 45 7e-05 5I2T-A nrPDB 45 7e-05 5WYK-BB nrPDB 45 7e-05 3JAP-g nrPDB 44 1e-04 6HHQ-h nrPDB 44 2e-04 2C2V-S nrPDB 43 2e-04 2C2L-A nrPDB 43 2e-04 6CHG-A nrPDB 43 3e-04 2F42-A nrPDB 43 3e-04 2H9P-A nrPDB 42 6e-04 2OXQ-C nrPDB 42 7e-04 5WLC-LN nrPDB 41 0.001 6EMK-B nrPDB 41 0.001 5M25-A nrPDB 41 0.002 5MWJ-A nrPDB 39 0.005 3CRC-A nrPDB 39 0.006 4WZ3-B nrPDB 38 0.007 6GMH-W nrPDB 37 0.016 4WZ0-A nrPDB 36 0.055 3ACP-A nrPDB 35 0.062 4V7E-Bg nrPDB 34 0.11 2QJ0-A nrPDB 34 0.12 4E5Z-B nrPDB 34 0.12 5K19-A nrPDB 33 0.25 5K0Y-T nrPDB 33 0.27 3H15-A nrPDB 33 0.39 3DW8-B nrPDB 33 0.40 1WGM-A nrPDB 32 0.81 3MKQ-A nrPDB 31 0.92 2YNP-A nrPDB 31 0.92 1J37-A nrPDB 31 0.95 6EOJ-D nrPDB 31 1.1 2P9P-C nrPDB 31 1.1 3PXI-A nrPDB 31 1.5 3PXG-A nrPDB 31 1.5 3J3U-A nrPDB 31 1.5 3HTK-C nrPDB 30 1.9 >5LJ5-t nrPDB Length = 503 Score = 858 bits (2217), Expect = 0.0, Method: Composition-based stats. Identities = 503/503 (100%), Positives = 503/503 (100%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA 60 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA Sbjct: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA 60 Query: 61 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK 120 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK Sbjct: 61 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK 120 Query: 121 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNL 180 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNL Sbjct: 121 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNL 180 Query: 181 ELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPR 240 ELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPR Sbjct: 181 ELLQAQNYSRNIKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPR 240 Query: 241 TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTE 300 TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTE Sbjct: 241 TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTE 300 Query: 301 YFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLS 360 YFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLS Sbjct: 301 YFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLS 360 Query: 361 SPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFK 420 SPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFK Sbjct: 361 SPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFK 420 Query: 421 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVV 480 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVV Sbjct: 421 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVV 480 Query: 481 CGDGGIAAILKTNDSFNIVALTP 503 CGDGGIAAILKTNDSFNIVALTP Sbjct: 481 CGDGGIAAILKTNDSFNIVALTP 503 >4ZB4-A nrPDB Length = 360 Score = 659 bits (1700), Expect = 0.0, Method: Composition-based stats. Identities = 360/360 (100%), Positives = 360/360 (100%) Query: 144 AVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKS 203 AVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKS Sbjct: 1 AVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPYKELNKS 60 Query: 204 MYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPG 263 MYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPG Sbjct: 61 MYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISRGPCNRLLLLYPG 120 Query: 264 NQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYI 323 NQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYI Sbjct: 121 NQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYI 180 Query: 324 VHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFA 383 VHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFA Sbjct: 181 VHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFA 240 Query: 384 DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESN 443 DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESN Sbjct: 241 DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESN 300 Query: 444 SLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP 503 SLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP Sbjct: 301 SLTIYKFDKKTKNWTKDEESALCLQSDTADFTDMDVVCGDGGIAAILKTNDSFNIVALTP 360 >3JB9-S nrPDB Length = 488 Score = 504 bits (1297), Expect = e-143, Method: Composition-based stats. Identities = 131/509 (25%), Positives = 215/509 (42%), Gaps = 109/509 (21%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEI-VPSAQQ 59 M C+ISG+ P+ PV+S S ++EK L+EQ +++T DP+T + ++E++V + VP + Sbjct: 1 MFCSISGETPKEPVISRVSGNVYEKRLIEQVIRETSKDPVTQQECTLEDLVPVKVPDFVR 60 Query: 60 ASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAA 119 +T S+P LL+ Q EWD++ LE F+LR L ++LST +Y DAA Sbjct: 61 PRPPSAT---------SLPALLSLFQEEWDSVALEQFELRRNLTETKQELSTALYSLDAA 111 Query: 120 KLVAAQLLMEKN-----------------------------EDSKDLPKSSQQAVAITRE 150 V ++L E++ E L S + V T + Sbjct: 112 LRVISRLTKERDEAREALAKFSDNIGTVSSKTIEVQEVEMGESDDQLKTSLRSTVEKTFQ 171 Query: 151 EFLQGLLQSSRDFVARGKLKAPKWPILKNL-ELLQAQNYS--RNIKT------FPYKELN 201 E L S R R KL+ PKW + +LLQA + N++T FP E + Sbjct: 172 E-----LSSKRK---RTKLQ-PKWATDDAVSQLLQATPSTILENLETESTTSFFPSPENS 222 Query: 202 K---SMYYDKWVC--------MCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIIS 250 ++ D+ +C + E AL L SK + T + + E P + S Sbjct: 223 SFVLCLHKDELLCLDIQSNSTLKIFEGSALACCWLTSSKI--AVATADAISIFEFP-VSS 279 Query: 251 RGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGT 310 G + + P + I I D K N ++ H + EY + A N Sbjct: 280 SGLQS---VGEPTSSIPI-DEKVN---------------FLQAHP--SGEYLLAASNEKC 318 Query: 311 IGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFP 370 F V++ +S +H D L +G L + SS ++ + P Sbjct: 319 YIFSLKSQ-----VYNITVAQHITSLAVHPDGNLFVAGLENGELRFFETSSGNELTKFGP 373 Query: 371 VDEEAKIKEVKFADNGYWMVVEC--DQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDI 428 + +K ++F +NGYW+VV D + +DLRK P T K V+ DI Sbjct: 374 --HSSPVKTLQFGENGYWLVVTTNDDSDIFIWDLRKSELVQKIPLQT----KVAAVSLDI 427 Query: 429 DDSGKNMIAYSNESNSLTIYKFDKKTKNW 457 + + S++ +L ++ + K +K+W Sbjct: 428 ----TSQLLVSSDGETLYVHIYVKSSKSW 452 >5Z56-q nrPDB Length = 504 Score = 248 bits (633), Expect = 3e-66, Method: Composition-based stats. Identities = 106/486 (21%), Positives = 191/486 (39%), Gaps = 48/486 (9%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEIVPSAQQA 60 ++C+IS +VP P +SP S ++E+ L+E+Y+ + G DPI N+PLS E++++I Sbjct: 3 LICSISNEVPEHPCVSPVSNHVYERRLIEKYIAENGTDPINNQPLSEEQLIDI---KVAH 59 Query: 61 SLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAAK 120 + SAT SIP +L +LQ+EWDA+ML +F LR L + ++LS +Y+ DAA Sbjct: 60 PIRPKPPSAT-----SIPAILKALQDEWDAVMLHSFTLRQQLQTTRQELSHALYQHDAAC 114 Query: 121 LVAAQLLMEKNEDSKDLPKSSQQAVAITREEFL--QGLLQSSRDFVARGKLKAPKWPILK 178 V A+L E + L QA I + Q + + + + G+L I++ Sbjct: 115 RVIARLTKEVTAAREALATLKPQAGLIVPQAVPSSQPSVVGAGEPMDLGELVGMTPEIIQ 174 Query: 179 NLE---LLQAQNYSRNIKTFPY---KELNKSMYYDKWVCMCRCEDG-----ALHFTQLKD 227 L+ + + KT P K S Y + AL Sbjct: 175 KLQDKATVLTTERKKRGKTVPEELVKPEELSKYRQVASHVGLHSASIPGILALDLCPSDT 234 Query: 228 SKTITTITTPNPR----TGGEHPAIISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVD 283 +K +T N + + A + +++ +Q + + + +R V Sbjct: 235 NKILTGGADKNVVVFDKSSEQILATLKGHTKKVTSVVFHPSQDLVFSASPDATIRIWSVP 294 Query: 284 SANEIIYMYGHNE--------VNTEYFIWADNRGTIGFQ-SYEDDSQYIVHSAKSDVEYS 334 +A+ + + H +Y + + + F V S + Sbjct: 295 NASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAFSDIQTGRVLTKVTDETSGCSLT 354 Query: 335 SGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVEC- 393 H D L+ + D + +++L ++ I + F++NGY++ Sbjct: 355 CAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANF--PGHSGPITSIAFSENGYYLATAAD 412 Query: 394 DQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKK 453 D +V +DLRK E K + D SG + + + + Sbjct: 413 DSSVKLWDLRKLKNFKTLQLDNNFEVK----SLIFDQSGTYLALGGTD-----VQIYI-- 461 Query: 454 TKNWTK 459 K WT+ Sbjct: 462 CKQWTE 467 >5M88-A nrPDB Length = 136 Score = 191 bits (486), Expect = 5e-49, Method: Composition-based stats. Identities = 50/140 (35%), Positives = 84/140 (60%), Gaps = 8/140 (5%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIVEIVPSAQQ 59 MLCA+SG++P PV+S K+ +FEK L+ +Y+++ N +P T E L E +++P Sbjct: 1 MLCALSGEIPEEPVVSKKTGVLFEKRLILKYLEEHNNIEPGTTEELDPE--TDLLPIKTS 58 Query: 60 ASLTESTNSATLKANYSIPNLLTSLQNEWDAIMLENFKLRSTLDSLTKKLSTVMYERDAA 119 + + T SIP+LL + Q+EWDA++LE + R L + ++L+T +Y+ DAA Sbjct: 59 RVVRPRPPNFT-----SIPSLLKAFQDEWDALVLETYTTREQLARVREELATALYQHDAA 113 Query: 120 KLVAAQLLMEKNEDSKDLPK 139 V A+L E++E + L + Sbjct: 114 VRVIARLTRERDEAREALAR 133 >5M89-A nrPDB Length = 329 Score = 90.3 bits (222), Expect = 2e-18, Method: Composition-based stats. Identities = 62/332 (18%), Positives = 119/332 (35%), Gaps = 45/332 (13%) Query: 133 DSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPK-WPILKNLELLQAQNYSR- 190 DS+ L + + V +++ ++ R K P+ W ++ LQ Y+ Sbjct: 2 DSESLSEGLVEHVNEVQQQLMK----------TRKKRPIPQGWATADDVAALQQVAYTDL 51 Query: 191 NIKTFPYKELNKSMYYDKWVCMCRCE-DGALHFTQLKDSKTITTITTPNPRTGGEHPAII 249 N+ +L C DG L + +K T+ P T E Sbjct: 52 NVTQASSLDLENE-------CAAVGGLDGKLDIYSVVANKVERTLDIGEPVTATEWTG-- 102 Query: 250 SRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRG 309 ++++ + + D+ + A + + H Sbjct: 103 -----TKVVIGTAKGWVKVYDAGRESATFQTH---AGPVTGLAVHP--GGRILASVGVDK 152 Query: 310 TIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRF 369 + F Y+ ++ V +D ++ H D L A + G + V++ ++ +QA S F Sbjct: 153 SFVF--YDLETGERVARGYADAALTTCAFHPDGNLFAAGTQTGHILVFHTTTLEQAES-F 209 Query: 370 PVDEEAKIKEVKFADNGYWMVVECD--QTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYD 427 P+ I+ + F++NG+W +V FDLRK A + E +TG V Sbjct: 210 PLG--TPIQALAFSENGFWFAATGKGTSSVTIFDLRKSGAAAA-----VKELQTGEV-LS 261 Query: 428 IDDSGKNMIAYSNESNSLTIYKFDKKTKNWTK 459 I + +T+ + K TK+W++ Sbjct: 262 ISWDYTGQYLATGGGTGVTVQMYTKATKSWSE 293 >4LG8-A nrPDB Length = 354 Score = 67.6 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 33/212 (15%), Positives = 71/212 (33%), Gaps = 24/212 (11%) Query: 258 LLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEV--------NTEYFIWADNRG 309 ++ +P + + + + +R V +A+ + + H +Y + + + Sbjct: 120 VVFHPSQDL-VFSASPDATIRIWSVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQ 178 Query: 310 TIGFQ-SYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSR 368 F V S + H D L+ + D + +++L ++ Sbjct: 179 YWAFSDIQTGRVLTKVTDETSGCSLTCAQFHPDGLIFGTGTMDSQIKIWDLKERTNVANF 238 Query: 369 FPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYD 427 I + F++NGY++ D +V +DLRK E K + Sbjct: 239 --PGHSGPITSIAFSENGYYLATAADDSSVKLWDLRKLKNFKTLQLDNNFEVK----SLI 292 Query: 428 IDDSGKNMIAYSNESNSLTIYKFDKKTKNWTK 459 D SG + + + + K WT+ Sbjct: 293 FDQSGTYLALGGTD-----VQIYI--CKQWTE 317 Score = 32.5 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 14/106 (13%), Positives = 35/106 (33%), Gaps = 4/106 (3%) Query: 295 NEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGIL 354 + ++ + F + + + +S V H L+ SPD + Sbjct: 81 PSDTNKILTGGADKNVVVFDKSSEQILATLKGHT--KKVTSVVFHPSQDLVFSASPDATI 138 Query: 355 DVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCF 400 ++ S P+ + + E+ + + G +++ D F Sbjct: 139 RIW--SVPNASCVQVVRAHESAVTGLSLHATGDYLLSSSDDQYWAF 182 >5OPT-p nrPDB Length = 318 Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 46/238 (19%), Positives = 82/238 (34%), Gaps = 38/238 (15%) Query: 249 ISRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYG---HNEVNTEYFIWA 305 + G C L + + +++ S N+ + D+A + + G H + W Sbjct: 96 LQTGVCQHKFLGHTKDVLSVTFSPDNRQIVSGGRDNALRVWNVKGECLHTLGRGAHTDWV 155 Query: 306 DNRGTIGFQSYED---------DSQYIVHSAKSDV----------EYSSGVLHKDSLLLA 346 + F + D+ V S +S + D L A Sbjct: 156 S---CVRFSPSLETPLIVSGGWDNLVKVWDIASGRLLTDLKGHTNYITSVTVSPDGSLCA 212 Query: 347 LYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLR-KD 405 DG+ +++L+ + S + A I ++ F+ N YWM ++ + FDL KD Sbjct: 213 SSDKDGVARLWDLTKGEALSE---MAAGAPINQICFSPNRYWMCAATEKGIRIFDLENKD 269 Query: 406 VGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEES 463 V P KT IA+S + N+L D + W+ E + Sbjct: 270 VIVELAPEAQQKSKKTPECM---------SIAWSADGNTLYSGYTDNVIRVWSVSEHA 318 >4V8M-A7 nrPDB Length = 318 Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 52/133 (39%), Gaps = 13/133 (9%) Query: 332 EYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVV 391 +S + D L A DG+ +++L+ + S + A I ++ F+ N YWM Sbjct: 198 YVTSVTVSPDGSLCASSDKDGVARLWDLTKGEALSE---MAAGAPINQICFSPNRYWMCA 254 Query: 392 ECDQTVVCFDLR-KDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKF 450 ++ + FDL KD+ P + + IA+S + ++L Sbjct: 255 ATEKGIRIFDLENKDIIVELAPEHQGSKKIVPECV---------SIAWSADGSTLYSGYT 305 Query: 451 DKKTKNWTKDEES 463 D + W E + Sbjct: 306 DNVIRVWGVSENA 318 >3DM0-A nrPDB Length = 694 Score = 49.1 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 47/130 (36%), Gaps = 7/130 (5%) Query: 332 EYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVV 391 S+ + D L A DG++ +++L+ + S ++ + I + F+ N YW+ Sbjct: 563 YVSTVAVSPDGSLCASGGKDGVVLLWDLAEGKKLYS---LEANSVIHALCFSPNRYWLCA 619 Query: 392 ECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGK----NMIAYSNESNSLTI 447 + + +DL E + + K + +S + ++L Sbjct: 620 ATEHGIKIWDLESKSIVEDLKVDLKAEAEKADNSGPAATKRKVIYCTSLNWSADGSTLFS 679 Query: 448 YKFDKKTKNW 457 D + W Sbjct: 680 GYTDGVIRVW 689 >6G51-g nrPDB Length = 317 Score = 47.9 bits (112), Expect = 9e-06, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 44/126 (34%), Gaps = 9/126 (7%) Query: 332 EYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVV 391 ++ + D L A DG +++L+ + +D I + F+ N YW+ Sbjct: 194 YLNTVTVSPDGSLCASGGKDGQAMLWDLNEGKHL---YTLDGGDIINALCFSPNRYWLCA 250 Query: 392 ECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFD 451 ++ +DL + I + + + +A+S + +L D Sbjct: 251 ATGPSIKIWDLEGKIIVDELKQEVI------STSSKAEPPQCTSLAWSADGQTLFAGYTD 304 Query: 452 KKTKNW 457 + W Sbjct: 305 NLVRVW 310 >4V6W-Ag nrPDB Length = 318 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 46/128 (35%), Gaps = 13/128 (10%) Query: 332 EYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVV 391 ++ + D L D +++L+ + ++ I + F+ N YW+ V Sbjct: 195 YLNTVTVSPDGSLCTSGGKDSKALLWDLNDGKNL---YTLEHNDIINALCFSPNRYWLCV 251 Query: 392 ECDQTVVCFDL--RKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYK 449 ++ +DL +K V L P P K D +A+S + +L Sbjct: 252 AYGPSIKIWDLACKKTVEELR-PEVVSPTSKA-------DQPQCLSLAWSTDGQTLFAGY 303 Query: 450 FDKKTKNW 457 D + W Sbjct: 304 SDNTIRVW 311 >5WLC-LO nrPDB Length = 923 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 39/106 (36%), Gaps = 3/106 (2%) Query: 298 NTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVY 357 E+ + ++ YI+ +S D + S DG + V+ Sbjct: 313 TGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVW 372 Query: 358 NLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDL 402 +++S ++ + + + V+FA G M D TV +DL Sbjct: 373 DITSGFCLATF--EEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDL 416 Score = 36.0 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 44/131 (33%), Gaps = 17/131 (12%) Query: 339 HKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVV 398 H + LLA+ G +Y+L PD + + + V G W+ Sbjct: 269 HPATRLLAVGFTSGEFRLYDL--PDFTLIQQLSMGQNPVNTVSVNQTGEWLA-------- 318 Query: 399 CFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWT 458 F K L Y + +D N +AYS + + + D K K W Sbjct: 319 -FGSSKLGQLLVYEWQSESYILKQQGHFD----STNSLAYSPDGSRVVTASEDGKIKVW- 372 Query: 459 KDEESALCLQS 469 D S CL + Sbjct: 373 -DITSGFCLAT 382 >5I2T-A nrPDB Length = 742 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 20/106 (18%), Positives = 39/106 (36%), Gaps = 3/106 (2%) Query: 298 NTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVY 357 E+ + ++ YI+ +S D + S DG + V+ Sbjct: 338 TGEWLAFGSSKLGQLLVYEWQSESYILKQQGHFDSTNSLAYSPDGSRVVTASEDGKIKVW 397 Query: 358 NLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDL 402 +++S ++ + + + V+FA G M D TV +DL Sbjct: 398 DITSGFCLATF--EEHTSSVTAVQFAKRGQVMFSSSLDGTVRAWDL 441 Score = 36.0 bits (81), Expect = 0.041, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 44/131 (33%), Gaps = 17/131 (12%) Query: 339 HKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVV 398 H + LLA+ G +Y+L PD + + + V G W+ Sbjct: 294 HPATRLLAVGFTSGEFRLYDL--PDFTLIQQLSMGQNPVNTVSVNQTGEWLA-------- 343 Query: 399 CFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWT 458 F K L Y + +D N +AYS + + + D K K W Sbjct: 344 -FGSSKLGQLLVYEWQSESYILKQQGHFD----STNSLAYSPDGSRVVTASEDGKIKVW- 397 Query: 459 KDEESALCLQS 469 D S CL + Sbjct: 398 -DITSGFCLAT 407 >5WYK-BB nrPDB Length = 943 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 21/81 (25%), Positives = 38/81 (46%), Gaps = 3/81 (3%) Query: 332 EYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVV 391 E + HKD+ LLA+ DG++ V++L S + +A I ++F G ++ Sbjct: 81 ECTYLEAHKDTDLLAVGYADGVIKVWDLMSKTVLLNF--NGHKAAITLLQFDGTGTRLIS 138 Query: 392 -ECDQTVVCFDLRKDVGTLAY 411 D ++ +DL +VG Sbjct: 139 GSKDSNIIVWDLVGEVGLYKL 159 >3JAP-g nrPDB Length = 326 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 58/154 (37%), Gaps = 19/154 (12%) Query: 304 WADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPD 363 W+ N SY ++ +I H+ +V S D L A DG + V+NL Sbjct: 186 WSLNE-----DSYRIEADFIGHNNYINVVQPS----PDGSLAASAGKDGQIYVWNLK--- 233 Query: 364 QASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGT 423 S+ D + ++ + F+ + +W+ + +DL +V PEF T Sbjct: 234 HKSAFMNFDAKDEVFALAFSPSRFWLTAATASGIKIYDLENEVLIDEL----KPEFAGYT 289 Query: 424 VTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNW 457 D +A+S + +L D + W Sbjct: 290 KA---QDPHAVSLAWSADGQTLFAGYTDNVIRVW 320 >6HHQ-h nrPDB Length = 319 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 58/160 (36%), Gaps = 19/160 (11%) Query: 302 FIWADNRG---TIGFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYN 358 I A N ++ ++ +I H++ ++ D L+A DG + ++N Sbjct: 169 IISAGNDKMVKAWNLNQFQIEADFIGHNS----NINTLTASPDGTLIASAGKDGEIMLWN 224 Query: 359 LSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPE 418 L++ + DE + + F+ N YW+ + F L P Y + + Sbjct: 225 LAAKKAMYTLSAQDE---VFSLAFSPNRYWLAAATATGIKVFSLD--------PQYLVDD 273 Query: 419 FKTGTVTYD-IDDSGKNMIAYSNESNSLTIYKFDKKTKNW 457 + Y + +A+S + +L D + W Sbjct: 274 LRPEFAGYSKAAEPHAVSLAWSADGQTLFAGYTDNVIRVW 313 >2C2V-S nrPDB Length = 78 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIVEIVPSA 57 LC IS ++ R P ++P S +++ +E++++ G+ +P+T PL+ E+++ + Sbjct: 6 LCGKISFELMREPCITP-SGITYDRKDIEEHLQRVGHFNPVTRSPLTQEQLIPNLAMK 62 >2C2L-A nrPDB Length = 281 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIVEIVPSA 57 LC IS ++ R P ++P S +++ +E++++ G+ +P+T PL+ E+++ + Sbjct: 209 LCGKISFELMREPCITP-SGITYDRKDIEEHLQRVGHFNPVTRSPLTQEQLIPNLAMK 265 >6CHG-A nrPDB Length = 312 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 52/221 (23%), Positives = 84/221 (38%), Gaps = 32/221 (14%) Query: 270 DSKTNKVLREIEVDSANEIIY-----MYGH--NEVNTEYFIWADNRGTIGFQSYEDDSQY 322 DSK E IIY + GH ++ Y +N+G I S D+S Sbjct: 65 DSKCIASGSEDFTVEITHIIYGRIRRLMGHTAPVISICY----NNKGNILCSSSMDESIK 120 Query: 323 IVH----------SAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASS----- 367 H SA SD S + DS +L+ S DG++ +++ S + Sbjct: 121 EWHVLSGTALKTMSAHSDAVVSIDIPKFDSSILSSGSYDGLIRIFDTESGHCLKTLTYDK 180 Query: 368 -RFPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDLRKDVGTLAY--PTY-TIPEFKTG 422 D I VKF+ NG +++V+ D V ++ + + P T + K Sbjct: 181 DWIAEDGVVPISTVKFSRNGKFLLVKSLDNVVKLWEYTRGTVVRTFLWPHQETKAKLKYN 240 Query: 423 TVTYDIDDSGKNMIAYS-NESNSLTIYKFDKKTKNWTKDEE 462 I GK+ + S N+S S+ ++ K DE+ Sbjct: 241 CGLELIYPQGKDPLVISGNDSGSMCVWNVYSKNLVQKIDEK 281 >2F42-A nrPDB Length = 179 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 35/58 (60%), Gaps = 3/58 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIVEIVPSA 57 LC IS ++ R P ++P S +++ +E++++ G+ DP+T PL+ ++++ + Sbjct: 107 LCGKISFELMREPCITP-SGITYDRKDIEEHLQRVGHFDPVTRSPLTQDQLIPNLAMK 163 >2H9P-A nrPDB Length = 329 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 38/222 (17%), Positives = 71/222 (31%), Gaps = 28/222 (12%) Query: 250 SRGPCNRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRG 309 S G N + K N L+ + + N E+ + Sbjct: 8 SSGRENLYFQGTQSKPTPV---KPNYALKFTLAGHTKAVSSVKFSP--NGEWLASSSADK 62 Query: 310 TI-GFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSR 368 I + +Y+ + + K S DS LL S D L ++++SS + Sbjct: 63 LIKIWGAYDGKFEKTISGHKLG--ISDVAWSSDSNLLVSASDDKTLKIWDVSSGKCLKTL 120 Query: 369 FPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYD 427 + F +V D++V +D++ P ++ P V ++ Sbjct: 121 --KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHSDP---VSAVHFN 175 Query: 428 IDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQS 469 D S + S+ +D + W D S CL++ Sbjct: 176 RDGS----LIVSSS--------YDGLCRIW--DTASGQCLKT 203 >2OXQ-C nrPDB Length = 80 Score = 41.8 bits (96), Expect = 7e-04, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 34/58 (58%), Gaps = 3/58 (5%) Query: 2 LCA-ISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGN-DPITNEPLSIEEIVEIVPSA 57 LC IS ++ P ++P S +++ +E++++ G+ DP+T PL+ ++++ + Sbjct: 14 LCGKISFELMAEPCITP-SGITYDRKDIEEHLQRVGHFDPVTRSPLTQDQLIPNLAMK 70 >5WLC-LN nrPDB Length = 776 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 31/85 (36%), Gaps = 5/85 (5%) Query: 326 SAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEE----AKIKEVK 381 + K D S+ L D +L + P + ++ +D + K VK Sbjct: 421 TLKDDQNISTCSLSPDGQVLVVGRPSTTKVFHLQPVGNKL-KVTKLDNDLLLRTSTKLVK 479 Query: 382 FADNGYWMVVECDQTVVCFDLRKDV 406 F DN ++ C+ V DL + Sbjct: 480 FIDNSKIVICSCEDDVFIVDLESEE 504 >6EMK-B nrPDB Length = 303 Score = 40.6 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 30/201 (14%), Positives = 73/201 (36%), Gaps = 21/201 (10%) Query: 274 NKVLREIEVDSANEIIYMYGHN--------EVNTEYFIWADNRGTIGFQSYEDDSQYIVH 325 N L +I + N + GH + + + + + GTI + ++ S I Sbjct: 54 NVRLYDIRTTNPNPVASFEGHRGNVTSVSFQQDNRWMVTSSEDGTI--KVWDVRSPSIPR 111 Query: 326 SAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADN 385 + K + + V+H + L DG + +++L +Q + + +++ ++ + A + Sbjct: 112 NYKHNAPVNEVVIHPNQGELISCDRDGNIRIWDLGE-NQCTHQLTPEDDTSLQSLSMASD 170 Query: 386 GYWM-VVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNS 444 G + +++ P +T + + I S++ Sbjct: 171 GSMLAAANTKGNCYVWEM---------PNHTDASHLKPVTKFRAHSTYITRILLSSDVKH 221 Query: 445 LTIYKFDKKTKNWTKDEESAL 465 L D + W+ D++ L Sbjct: 222 LATCSADHTARVWSIDDDFKL 242 >5M25-A nrPDB Length = 434 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 32/174 (18%), Positives = 61/174 (35%), Gaps = 23/174 (13%) Query: 298 NTEYFIWADNRGTI-GFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDV 356 N E+ + I + +Y+ + + K S DS LL S D L + Sbjct: 156 NGEWLASSSADKLIKIWGAYDGKFEKTISGHKLG--ISDVAWSSDSNLLVSASDDKTLKI 213 Query: 357 YNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDLRKDVGTLAYPTYT 415 +++SS + + F +V D++V +D++ P ++ Sbjct: 214 WDVSSGKCLKTL--KGHSNYVFCCNFNPQSNLIVSGSFDESVRIWDVKTGKCLKTLPAHS 271 Query: 416 IPEFKTGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQS 469 P V ++ D S + S+ +D + W D S CL++ Sbjct: 272 DP---VSAVHFNRDGS----LIVSSS--------YDGLCRIW--DTASGQCLKT 308 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 26/109 (23%), Positives = 40/109 (36%), Gaps = 18/109 (16%) Query: 362 PDQASSRFPVDEEAKIKEVKFADNGYWMVVEC-DQTVVCFDLRKDVGTLAYPTYTIPEFK 420 P+ A + VKF+ NG W+ D+ + + TI K Sbjct: 133 PNYALKFTLAGHTKAVSSVKFSPNGEWLASSSADKLIKIWGAYDGKFE-----KTISGHK 187 Query: 421 TGTVTYDIDDSGKNMIAYSNESNSLTIYKFDKKTKNWTKDEESALCLQS 469 G + +A+S++SN L DK K W D S CL++ Sbjct: 188 LGI----------SDVAWSSDSNLLVSASDDKTLKIW--DVSSGKCLKT 224 >5MWJ-A nrPDB Length = 337 Score = 39.1 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 45/151 (29%), Gaps = 28/151 (18%) Query: 330 DVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPD-----QASSRFPVDEEAKIKEVKFAD 384 D S L D L + L +++L++P + +S P I D Sbjct: 97 DNYIRSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAISP----D 152 Query: 385 NGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSNESNS 444 + D + +DL + +T G + I SN+ Sbjct: 153 SKVCFSCCSDGNIAVWDLHNQTLVRQFQGHT---------------DGASCIDISNDGTK 197 Query: 445 LTIYKFDKKTKNWTKDEESALCLQSDTADFT 475 L D ++W E L DFT Sbjct: 198 LWTGGLDNTVRSWDLREGRQL----QQHDFT 224 >3CRC-A nrPDB Length = 265 Score = 38.7 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 55/136 (40%), Gaps = 9/136 (6%) Query: 41 TNEPLSIEEIVEIVPSAQQASLTESTNSATLKANYSIPNLLTS--LQNEWDAIMLENFKL 98 ++ S E + + ++ +SA S+P L+ + +Q + + L Sbjct: 105 SSAENSSEVLARWEQIKTEERAQKAQHSALDDIPRSLPALMRAQKIQKRCANVGFDWTTL 164 Query: 99 RSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNE-------DSKDLPKSSQQAVAITREE 151 +D + +++ VMYE A + A+L E + ++ L ++ A+ E+ Sbjct: 165 GPVVDKVYEEIDEVMYEARQAVVDQAKLEEEMGDLLFATVNLARHLGTKAEIALQKANEK 224 Query: 152 FLQGLLQSSRDFVARG 167 F + + R ARG Sbjct: 225 FERRFREVERIVAARG 240 >4WZ3-B nrPDB Length = 215 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 40/93 (43%), Gaps = 3/93 (3%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVEI--VPSAQ 58 + C I + PV++P ++ KS + ++++ DP + +PL+ +++ + Sbjct: 35 LTCPIDSGFLKDPVITP-EGFVYNKSSILKWLETKKEDPQSRKPLTAKDLQPFPELLIIV 93 Query: 59 QASLTESTNSATLKANYSIPNLLTSLQNEWDAI 91 + TN LK + + Q E+ I Sbjct: 94 NRFVETQTNYEKLKNRLVQNARVAARQKEYTEI 126 >6GMH-W nrPDB Length = 305 Score = 37.1 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 16/112 (14%), Positives = 42/112 (37%), Gaps = 6/112 (5%) Query: 298 NTEYFIWADNRGTI-GFQSYEDDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDV 356 +++Y + G + F +Y + S D LA + DGI+++ Sbjct: 117 DSQYLATGTHVGKVNIFGVESGKKEYSLD--TRGKFILSIAYSPDGKYLASGAIDGIINI 174 Query: 357 YNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQT-VVCFDLRKDVG 407 +++++ + I+ + F+ + +V D + +D++ Sbjct: 175 FDIATGKLLHTL--EGHAMPIRSLTFSPDSQLLVTASDDGYIKIYDVQHANL 224 >4WZ0-A nrPDB Length = 109 Score = 35.6 bits (80), Expect = 0.055, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 28/52 (53%), Gaps = 1/52 (1%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVE 52 + C I + PV++P ++ KS + ++++ DP + +PL+ +++ Sbjct: 27 LTCPIDSGFLKDPVITP-EGFVYNKSSILKWLETKKEDPQSRKPLTAKDLQP 77 >3ACP-A nrPDB Length = 417 Score = 35.2 bits (79), Expect = 0.062, Method: Composition-based stats. Identities = 57/326 (17%), Positives = 115/326 (35%), Gaps = 28/326 (8%) Query: 132 EDSKDLPKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRN 191 + SK L ++ AV + + + +L ++ + K+ + + + ++ ++ Sbjct: 86 DGSKMLKRADYTAVDTAKLQMRRFILGTTEGDI---KVLDSNFNLQREIDQAHVSEITK- 141 Query: 192 IKTFPYKELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPNPRTGGEHPAIISR 251 +K FP E S D + + +DG+ T + T+T I + ++S Sbjct: 142 LKFFPSGEALISSSQDMQLKIWSVKDGSNPRTLIGHRATVTDIAIID-----RGRNVLSA 196 Query: 252 GPCNRLLLLYPGNQITI--------LDSKTNKVLREIEVDSANEIIYMYGHNEVN----T 299 + L G TI N + + D I N + Sbjct: 197 SLDGTIRLWECGTGTTIHTFNRKENPHDGVNSIALFVGTDRQLHEISTSKKNNLEFGTYG 256 Query: 300 EYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLH-KDSLLLALYSPDGILDVYN 358 +Y I G I + Q I +K +S + ++ + +G+L ++ Sbjct: 257 KYVIAGHVSGVITVHNVFSKEQTIQLPSKFTCSCNSLTVDGNNANYIYAGYENGMLAQWD 316 Query: 359 LSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPE 418 L SP+ F ++E I V FA ++ D ++ + D+ + E Sbjct: 317 LRSPECPVGEFLINEGTPINNVYFAAGALFVSSGFDTSI-----KLDIISDPESERPAIE 371 Query: 419 FKTGTVTYDIDDSGKNMIAYSNESNS 444 F+T T DD + Y ++ S Sbjct: 372 FETPTFLVSNDDE-VSQFCYVSDDES 396 >4V7E-Bg nrPDB Length = 380 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 25/167 (14%), Positives = 53/167 (31%), Gaps = 20/167 (11%) Query: 291 MYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSGVLH----------K 340 + GH+ Y + + D + IV +A + + + LH Sbjct: 62 LQGHS--GKVYSLDWTPEKNWIVSA-SQDGRLIVWNALTSQKTHAIKLHCPWVMECAFAP 118 Query: 341 DSLLLALYSPDGILDVYNLSS-----PDQASSRFPVDEEAKIKEVKFADNGYWMVVE--C 393 + +A D ++NLSS + SR + ++ + ++ Sbjct: 119 NGQSVACGGLDSACSIFNLSSQADRDGNMPVSRVLTGHKGYASSCQYVPDQETRLITGSG 178 Query: 394 DQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDDSGKNMIAYSN 440 DQT V +D+ + + ++ I+ NM + Sbjct: 179 DQTCVLWDVTTGQRISIFGSEFPSGHTADVLSLSINSLNANMFISGS 225 >2QJ0-A nrPDB Length = 982 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 10/42 (23%), Positives = 22/42 (52%) Query: 11 RRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVE 52 + PV+ P S+ ++S ++ ++ DP PL +E++ Sbjct: 916 KDPVILPASKMNIDRSTIKAHLLSDSTDPFNRMPLKLEDVTP 957 >4E5Z-B nrPDB Length = 436 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 31/166 (18%), Positives = 64/166 (38%), Gaps = 7/166 (4%) Query: 255 NRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQ 314 + + + G I + + I+ A I N +NT F + GT Q Sbjct: 133 STVAVGSKGGDIMLWNFGIKDKPTFIKGIGAGGSITGLKFNPLNTNQFYASSMEGTTRLQ 192 Query: 315 SYEDDSQYIVHSA-KSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDE 373 ++ + + S+ ++ + S + S ++ G + + N+ + + R Sbjct: 193 DFKGNILRVFASSDTINIWFCSLDVSASSRMVVTGDNVGNVILLNMDGKELWNLRM---H 249 Query: 374 EAKIKEVKFADNGYWMVVEC--DQTVVCFDLRKDVGTLAYPTYTIP 417 + K+ V W + DQTV +DLR+ G ++ Y++P Sbjct: 250 KKKVTHVALNPCCDWFLATASVDQTVKIWDLRQVRGKASF-LYSLP 294 >5K19-A nrPDB Length = 569 Score = 33.3 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 22/147 (14%), Positives = 47/147 (31%), Gaps = 29/147 (19%) Query: 244 EHPAIISRGPCNRLLLLYPGNQITILD---SKTNKVLREIEVDSANEIIYMYGHNEVNTE 300 + + + LL+ + Q+ ++D +T+K+ E + + + + + Sbjct: 105 DFNHLTATAESVSLLVGFSAGQVQLIDPIKKETSKLFNEERLIDKSRVTCVKWVPGSESL 164 Query: 301 YFIWADNRGTIGF-------------QSYEDDSQYIVHSAKSDV-------------EYS 334 + + + + Q + + VH+ KS + Sbjct: 165 FLVAHSSGNMYLYNVEHTCGTTAPHYQLLKQGESFAVHTCKSKSTRNPLLKWTVGEGALN 224 Query: 335 SGVLHKDSLLLALYSPDGILDVYNLSS 361 D LA S DG L V+N S Sbjct: 225 EFAFSPDGKFLACVSQDGFLRVFNFDS 251 >5K0Y-T nrPDB Length = 329 Score = 33.3 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 38/212 (17%), Positives = 75/212 (35%), Gaps = 16/212 (7%) Query: 256 RLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNRGTIGFQS 315 RL G Q+ +L KTN +R D II ++ + F+ F Sbjct: 77 RLWDCETGKQLALL--KTNSAVRTCGFDFGGNIIMFSTDKQMGYQCFVS-------FFDL 127 Query: 316 YE----DDSQYIVHSAKSDVEYSSGVLHKDSLLLALYSPDGILDVYNLSSPDQASSRFPV 371 + D+++ + +D + +S V + G L+ Y+ S + + Sbjct: 128 RDPSQIDNNEPYMKIPCNDSKITSAVWGPLGECIIAGHESGELNQYSAKSGEVLVNV--K 185 Query: 372 DEEAKIKEVKFA-DNGYWMVVECDQTVVCFDLRKDVGTLAYPTYTIPEFKTGTVTYDIDD 430 + +I +++ + + ++ D T FD + T E + Y+ Sbjct: 186 EHSRQINDIQLSREMTMFVTASKDNTAKLFDSTTLEHQKTFRTEPPRELAALSPNYEHVV 245 Query: 431 SGKNMIAYSNESNSLTIYKFDKKTKNWTKDEE 462 G A + S I KF+ + + +EE Sbjct: 246 VGGGQEAMDVTTTSTRIGKFEARFFHLAFEEE 277 >3H15-A nrPDB Length = 198 Score = 32.5 bits (72), Expect = 0.39, Method: Composition-based stats. Identities = 34/174 (19%), Positives = 55/174 (31%), Gaps = 7/174 (4%) Query: 138 PKSSQQAVAITREEFLQGLLQSSRDFVARGKLKAPKWPILKNLELLQAQNYSRNIKTFPY 197 P+ S + L ++ +A KL+ W + S N KTF Sbjct: 20 PRVSSSEMERKMNGRKLIRLAQLQNKIATEKLEEEDWVTFGVIVKKITPQSSNNGKTFSI 79 Query: 198 KELNKSMYYDKWVCMCRCEDGALHFTQLKDSKTITTITTPN---PRTGGEHPAIISRGPC 254 LN DK++ + D T+ + N P+ G + + P Sbjct: 80 WRLNDLKDLDKYISLFLF-GDVHKEHWKTDQGTVIGLLNANPMKPKEGTDEVCLSVDNPQ 138 Query: 255 NRLLLLYPGNQITILDSKTNKVLREIEVDSANEIIYMYGHNEVNTEYFIWADNR 308 LL+ + T K N V+ N+ Y H V +Y + R Sbjct: 139 KVLLMGDAVDLGTCKARKKNGDPCTQMVN-LNDCEYCQYH--VQAQYKKVSSKR 189 >3DW8-B nrPDB Length = 447 Score = 32.5 bits (72), Expect = 0.40, Method: Composition-based stats. Identities = 27/153 (17%), Positives = 59/153 (38%), Gaps = 29/153 (18%) Query: 279 EIEVDSANEIIYMYGHN------EVNTEY--FIWADNRGTIGFQSYEDDSQYIVHSAKSD 330 ++ V+++ I+ H +N++Y ++ AD+ + D + + K Sbjct: 161 DLMVEASPRRIFANAHTYHINSISINSDYETYLSADDLRINLWHLEITDRSFNIVDIKPA 220 Query: 331 ------VEYSSGVLHKDS-LLLALYSPDGILDVYNLSSP---DQASSRF--PVDEE---- 374 ++ H +S S G + + ++ + D+ S F P D Sbjct: 221 NMEELTEVITAAEFHPNSCNTFVYSSSKGTIRLCDMRASALCDRHSKLFEEPEDPSNRSF 280 Query: 375 -----AKIKEVKFADNGYWMVVECDQTVVCFDL 402 + I +VKF+ +G +M+ +V +DL Sbjct: 281 FSEIISSISDVKFSHSGRYMMTRDYLSVKVWDL 313 >1WGM-A nrPDB Length = 98 Score = 31.7 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 11/41 (26%), Positives = 22/41 (53%) Query: 12 RPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLSIEEIVE 52 PV+ P SR ++S + +++ DP PL++++I Sbjct: 34 DPVVLPSSRVTVDRSTIARHLLSDQTDPFNRSPLTMDQIRP 74 >3MKQ-A nrPDB Length = 814 Score = 31.4 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 288 IIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSG---VLHKDSLL 344 + Y+ + + Y I A + TI Y+ S A + S+ V H + Sbjct: 187 VNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCV----ATLEGHMSNVSFAVFHPTLPI 242 Query: 345 LALYSPDGILDVYNLSS 361 + S DG L ++N S+ Sbjct: 243 IISGSEDGTLKIWNSST 259 >2YNP-A nrPDB Length = 604 Score = 31.4 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 31/77 (40%), Gaps = 7/77 (9%) Query: 288 IIYMYGHNEVNTEYFIWADNRGTIGFQSYEDDSQYIVHSAKSDVEYSSG---VLHKDSLL 344 + Y+ + + Y I A + TI Y+ S A + S+ V H + Sbjct: 187 VNYVDYYPLPDKPYMITASDDLTIKIWDYQTKSCV----ATLEGHMSNVSFAVFHPTLPI 242 Query: 345 LALYSPDGILDVYNLSS 361 + S DG L ++N S+ Sbjct: 243 IISGSEDGTLKIWNSST 259 >1J37-A nrPDB Length = 607 Score = 31.4 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 29/110 (26%), Positives = 47/110 (42%), Gaps = 9/110 (8%) Query: 90 AIMLENFKLRSTLDSLTKKLSTVM-YERDAAKLVAAQLLME----KNEDSKDLPKSSQQA 144 A++ E + + L++L K+L+ E +AA + + E KNE S +L K ++ Sbjct: 4 ALVKEEIQAKEYLENLNKELAKRTNVETEAAWAYRSAITDENEKKKNEISAELAKFMKEV 63 Query: 145 VAITREEFLQGLLQS---SRDFVARGKLKAPKWPILKNLELLQAQNYSRN 191 + T +F QS R F A KL P ELL + + Sbjct: 64 ASDT-TKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMES 112 >6EOJ-D nrPDB Length = 470 Score = 31.4 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 13/67 (19%), Positives = 26/67 (38%) Query: 339 HKDSLLLALYSPDGILDVYNLSSPDQASSRFPVDEEAKIKEVKFADNGYWMVVECDQTVV 398 H + L+A S D ++ +++ S + SS + M + D++ Sbjct: 228 HPEMGLIASASKDNLVKLWDPRSGNCISSILKFKHTVLKTRFQPTKGNLLMAISKDKSCR 287 Query: 399 CFDLRKD 405 FD+R Sbjct: 288 VFDIRYS 294 >2P9P-C nrPDB Length = 372 Score = 31.0 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 31/151 (20%), Positives = 52/151 (34%), Gaps = 29/151 (19%) Query: 304 WADNRGTIGFQS----------YEDDSQYIVHSAKSDVEYSSGVL--HKDSLLLALYSPD 351 WA N S +++ ++ K + + L H +S+LLA S D Sbjct: 104 WAPNEKKFAVGSGSRVISICYFEQENDWWVCKHIKKPIRSTVLSLDWHPNSVLLAAGSCD 163 Query: 352 GILDVY--------NLSSPDQASSRFPVDE---EAK-----IKEVKFADNGYWMV-VECD 394 ++ +P S+ P E E+ + V F+ NG + V D Sbjct: 164 FKCRIFSAYIKEVEERPAPTPWGSKMPFGELMFESSSSCGWVHGVCFSANGSRVAWVSHD 223 Query: 395 QTVVCFDLRKDVGTLAYPTYTIPEFKTGTVT 425 TV D K + + T+P +T Sbjct: 224 STVCLADADKKMAVATLASETLPLLAVTFIT 254 >3PXI-A nrPDB Length = 758 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 91 IMLENFKLRSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITRE 150 + L +F L L +KL V E+DAA EK +D + ++ V T++ Sbjct: 385 VRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQE---FEKAASLRDTEQRLREQVEDTKK 441 Query: 151 EFLQ 154 + + Sbjct: 442 SWKE 445 >3PXG-A nrPDB Length = 468 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 91 IMLENFKLRSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITRE 150 + L +F L L +KL V E+DAA EK +D + ++ V T++ Sbjct: 385 VRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQE---FEKAASLRDTEQRLREQVEDTKK 441 Query: 151 EFLQ 154 + + Sbjct: 442 SWKE 445 >3J3U-A nrPDB Length = 810 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 91 IMLENFKLRSTLDSLTKKLSTVMYERDAAKLVAAQLLMEKNEDSKDLPKSSQQAVAITRE 150 + L +F L L +KL V E+DAA EK +D + ++ V T++ Sbjct: 402 VRLRSFTTPPNLKELEQKLDEVRKEKDAAVQSQE---FEKAASLRDTEQRLREQVEDTKK 458 Query: 151 EFLQ 154 + + Sbjct: 459 SWKE 462 >3HTK-C nrPDB Length = 267 Score = 30.2 bits (66), Expect = 1.9, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 20/46 (43%) Query: 1 MLCAISGKVPRRPVLSPKSRTIFEKSLLEQYVKDTGNDPITNEPLS 46 + C I+ K P++S K +F++ ++ Y++ S Sbjct: 182 LTCPITCKPYEAPLISRKCNHVFDRDGIQNYLQGYTTRDCPQAACS 227 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.304 0.119 0.307 Lambda K H 0.267 0.0363 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,201,206 Number of Sequences: 36641 Number of extensions: 582434 Number of successful extensions: 1436 Number of sequences better than 10.0: 51 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1354 Number of HSP's gapped (non-prelim): 88 length of query: 503 length of database: 10,336,785 effective HSP length: 101 effective length of query: 402 effective length of database: 6,636,044 effective search space: 2667689688 effective search space used: 2667689688 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 61 (28.3 bits)