BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P32481 (527 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3J81-k nrPDB 1075 0.0 6O81-S nrPDB 684 0.0 6FEC-S nrPDB 661 0.0 1S0U-A nrPDB 396 e-110 2D74-A nrPDB 374 e-104 3PEN-A nrPDB 332 2e-91 5LZD-z nrPDB 91 1e-18 5IZL-A nrPDB 90 2e-18 4V5G-AZ nrPDB 86 4e-17 1D2E-A nrPDB 85 1e-16 5W7Q-A nrPDB 84 2e-16 3MMP-A nrPDB 81 9e-16 5W76-A nrPDB 80 2e-15 1EFM-A nrPDB 80 3e-15 1MJ1-A nrPDB 77 1e-14 5W75-A nrPDB 76 4e-14 4AC9-A nrPDB 75 8e-14 6MIJ-A nrPDB 74 1e-13 4J0Q-A nrPDB 74 2e-13 4ZV4-A nrPDB 73 3e-13 2HDN-B nrPDB 67 1e-11 4ZU9-A nrPDB 65 8e-11 3WY9-A nrPDB 62 8e-10 3WXM-A nrPDB 60 2e-09 1JNY-A nrPDB 59 6e-09 1ZUN-B nrPDB 49 8e-06 5LZT-jj nrPDB 47 2e-05 4D61-i nrPDB 47 3e-05 2B7C-A nrPDB 45 6e-05 3J4J-A nrPDB 45 6e-05 4KJZ-A nrPDB 45 7e-05 4B44-A nrPDB 45 7e-05 1G7S-A nrPDB 44 1e-04 3MCA-A nrPDB 43 3e-04 1R5O-A nrPDB 42 4e-04 5LZS-jj nrPDB 42 0.001 4C0S-A nrPDB 41 0.001 5FG3-A nrPDB 40 0.003 5YT0-A nrPDB 40 0.004 4V6V-A1 nrPDB 39 0.005 4V6W-Az nrPDB 39 0.005 2P8Y-T nrPDB 39 0.006 2LKD-A nrPDB 37 0.021 2YWH-A nrPDB 37 0.022 5LZY-jj nrPDB 36 0.052 2OKJ-A nrPDB 34 0.14 5KCS-1w nrPDB 34 0.15 3IZQ-1 nrPDB 34 0.17 3P27-A nrPDB 33 0.22 3JCN-b nrPDB 33 0.28 4CRN-P nrPDB 33 0.30 1ZO1-I nrPDB 33 0.38 4RXU-A nrPDB 32 0.45 3CB4-D nrPDB 32 0.65 4XKM-A nrPDB 32 1.00 3WNB-A nrPDB 31 1.4 6MTD-v nrPDB 31 1.6 6GB2-BC nrPDB 30 1.9 3IZY-P nrPDB 30 2.5 3IEU-A nrPDB 30 3.3 4UJC-AB nrPDB 29 4.7 2ZY3-A nrPDB 28 7.4 4C65-A nrPDB 28 10.0 >3J81-k nrPDB Length = 527 Score = 1075 bits (2781), Expect = 0.0, Method: Compositional matrix adjust. Identities = 527/527 (100%), Positives = 527/527 (100%) Query: 1 MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGET 60 MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGET Sbjct: 1 MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGET 60 Query: 61 EEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAI 120 EEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAI Sbjct: 61 EEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAI 120 Query: 121 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP 180 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP Sbjct: 121 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP 180 Query: 181 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK 240 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK Sbjct: 181 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK 240 Query: 241 LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK 300 LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK Sbjct: 241 LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK 300 Query: 301 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV 360 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV Sbjct: 301 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV 360 Query: 361 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK 420 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK Sbjct: 361 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK 420 Query: 421 GHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKA 480 GHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKA Sbjct: 421 GHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKA 480 Query: 481 DMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA 527 DMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA Sbjct: 481 DMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA 527 >6O81-S nrPDB Length = 472 Score = 684 bits (1766), Expect = 0.0, Method: Compositional matrix adjust. Identities = 326/444 (73%), Positives = 381/444 (85%), Gaps = 1/444 (0%) Query: 83 DFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGY 142 D +KL PLS E+I+RQATINIGTIGHVAHGKSTVV+AISGV TVRFK+ELERNITIKLGY Sbjct: 24 DVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGY 83 Query: 143 ANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMS 202 ANAKIYK +P+CP P+CYRS S PG G +KLVRHVSFVDCPGHDILM+ Sbjct: 84 ANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMA 143 Query: 203 TMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEH 262 TML+GAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKH++ILQNK+DL++E A E Sbjct: 144 TMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQ 203 Query: 263 QKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFD 322 + IL F++GT+A+GAPI+PISAQLKYNI+ V E+IVK IPVPPRDF PRLIVIRSFD Sbjct: 204 YEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFD 263 Query: 323 VNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFA 382 VNKPG E++DLKGGVAGGSIL GV K+G EIE+RPGIV+K +GK+ CKP FS IVSLFA Sbjct: 264 VNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKASEGKLMCKPKFSKIVSLFA 323 Query: 383 EQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLG 442 E NDL++A PGGLIGVGTK+DPTLCRADR+VGQV+GA G LP I+T++EI+YFLLRRLLG Sbjct: 324 EHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLG 383 Query: 443 VKTDGQKQ-AKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIAL 501 V+T+G K+ AKV+KL NEVLMVNIGS +TG RV AVKAD+ ++ LT+P CTE+ EKIAL Sbjct: 384 VRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIAL 443 Query: 502 SRRIEKHWRLIGWATIKKGTTLEP 525 SRR+EKHWRLIGW I++G T++P Sbjct: 444 SRRVEKHWRLIGWGQIRRGVTIKP 467 >6FEC-S nrPDB Length = 422 Score = 661 bits (1706), Expect = 0.0, Method: Compositional matrix adjust. Identities = 316/422 (74%), Positives = 365/422 (86%), Gaps = 1/422 (0%) Query: 98 QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE 157 QATINIGTIGHVAHGKSTVV+AISGV TVRFK+ELERNITIKLGYANAKIYK +P+CP Sbjct: 1 QATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPR 60 Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLL 217 P+CYRS S PG G +KLVRHVSFVDCPGHDILM+TML+GAAVMDAALLL Sbjct: 61 PECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLL 120 Query: 218 IAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADG 277 IAGNESCPQPQTSEHLAAIEIMKLKH++ILQNK+DL++E A E + IL F++GT+A+G Sbjct: 121 IAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEG 180 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGV 337 API+PISAQLKYNI+ V E+IVK IPVPPRDF PRLIVIRSFDVNKPG E++DLKGGV Sbjct: 181 APIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGV 240 Query: 338 AGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIG 397 AGGSIL GV K+G EIE+RPGIV+KD +GK+ CKPIFS IVSLFAE NDL++A PGGLIG Sbjct: 241 AGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIG 300 Query: 398 VGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQ-AKVRKL 456 VGTK+DPTLCRADR+VGQV+GA G LP I+T++EI+YFLLRRLLGV+T+G K+ AKV+KL Sbjct: 301 VGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKL 360 Query: 457 EPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWAT 516 NEVLMVNIGS +TG RV AVKAD+ ++ LT+P CTE+ EKIALSRR+EKHWRLIGW Sbjct: 361 SKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQ 420 Query: 517 IK 518 I+ Sbjct: 421 IR 422 >1S0U-A nrPDB Length = 408 Score = 396 bits (1017), Expect = e-110, Method: Compositional matrix adjust. Identities = 208/425 (48%), Positives = 286/425 (67%), Gaps = 21/425 (4%) Query: 95 INRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPT 154 + QA +NIG +GHV HGK+++ +A++GV T R +EL R I+I+LGYA+ +I KC Sbjct: 3 LGSQAEVNIGMVGHVDHGKTSLTKALTGVWTDRHSEELRRGISIRLGYADCEIRKC---- 58 Query: 155 CPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAA 214 P+ Y + P+C P C + +R VSFVD PGH+ LM+TMLSGA++MD A Sbjct: 59 -PQCGTYTT-------KPRC--PNCLAETEFLRRVSFVDSPGHETLMATMLSGASLMDGA 108 Query: 215 LLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI 274 +L+IA NE CPQPQT EHL A+EI+ + +II+QNK+DL+ E+ A E+ + I +F++GTI Sbjct: 109 ILVIAANEPCPQPQTKEHLMALEILGIDKIIIVQNKIDLVDEKQAEENYEQIKEFVKGTI 168 Query: 275 ADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLK 334 A+ API+PISA + NID + + I IP P RD +PR+ V RSFD+NKPG EI+DLK Sbjct: 169 AENAPIIPISAHHEANIDVLLKAIQDFIPTPKRDPDATPRMYVARSFDINKPGTEIKDLK 228 Query: 335 GGVAGGSILNGVFKLGDEIEIRPGI-VTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPG 393 GGV GG+I+ GVFK+GDEIEIRPGI VT+ + K KP+ + IVSL A L+ A PG Sbjct: 229 GGVLGGAIIQGVFKVGDEIEIRPGIKVTEGN--KTFWKPLTTKIVSLAAGNTILRKAHPG 286 Query: 394 GLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKV 453 GLIGVGT +DP L ++D L G VVG G LP I I I LL R++G K ++ K+ Sbjct: 287 GLIGVGTTLDPYLTKSDALTGSVVGLPGTLPPIREKITIRANLLDRVVGTK----EELKI 342 Query: 454 RKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIG 513 L EVLM+NIG+ T + + + D+A ++L P C EI +++A+SRR+ WRLIG Sbjct: 343 EPLRTGEVLMLNIGTATTAGVITSARGDIADIKLKLPICAEIGDRVAISRRVGSRWRLIG 402 Query: 514 WATIK 518 + TI+ Sbjct: 403 YGTIE 407 >2D74-A nrPDB Length = 419 Score = 374 bits (960), Expect = e-104, Method: Compositional matrix adjust. Identities = 195/424 (45%), Positives = 281/424 (66%), Gaps = 19/424 (4%) Query: 96 NRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTC 155 RQA +NIG +GHV HGK+T+ +A++GV T +EL R ITIK+G+A+A+I +C Sbjct: 7 TRQAEVNIGMVGHVDHGKTTLTKALTGVWTDTHSEELRRGITIKIGFADAEIRRCS---- 62 Query: 156 PEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAAL 215 +C R SP C P C + +R VSF+D PGH+ LM+TML+GA++MD A+ Sbjct: 63 ---NCGRY-----STSPIC--PYCGHETEFIRRVSFIDSPGHEALMTTMLAGASLMDGAI 112 Query: 216 LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIA 275 L+IA NE CP+PQT EHL A++I+ K++II QNK++L+ +E ALE+ + I +FI+GT+A Sbjct: 113 LVIAANEPCPRPQTREHLMALQIIGQKNIIIAQNKIELVDKEKALENYRQIKEFIKGTVA 172 Query: 276 DGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKG 335 + API+PISA NID + + I + IP P RD P+++V+RSFDVNKPG E L G Sbjct: 173 ENAPIIPISALHGANIDVLVKAIEEFIPTPKRDSNKPPKMLVLRSFDVNKPGTPPEKLVG 232 Query: 336 GVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGL 395 GV GSI+ G K+GDEIEIRPG V ++ G+I+ +PI + IVSL A ++ A PGGL Sbjct: 233 GVLDGSIVQGKLKVGDEIEIRPG-VPYEEHGRIKYEPITTEIVSLQAGGQFVEEAYPGGL 291 Query: 396 IGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRK 455 +G+GTK+DP L + D + G VVG G LP ++TD+ + LL R++G +++ V Sbjct: 292 VGIGTKLDPYLTKGDLMAGNVVGKPGKLPPVWTDLRLEVHLLERVVGT----EQELNVEP 347 Query: 456 LEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWA 515 ++ EVL++N+G+ T V A+ D L+L P C E E++A+SR+I WRLIG+ Sbjct: 348 IKRKEVLLLNVGTARTMGLVTALGKDEIELKLQIPVCAEPGERVAISRQIGSRWRLIGYG 407 Query: 516 TIKK 519 IK+ Sbjct: 408 IIKE 411 >3PEN-A nrPDB Length = 403 Score = 332 bits (851), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 177/423 (41%), Positives = 265/423 (62%), Gaps = 28/423 (6%) Query: 98 QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE 157 Q +NIG +GHV HGK+T+V+AI+G+ T + KLGYA I C+ +C + Sbjct: 6 QPEVNIGVVGHVDHGKTTLVQAITGIWTSK-----------KLGYAETNIGVCE--SCKK 52 Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLL 217 P+ Y + P C+ G K +R +SF+D PGH++LM+TMLSGAA+MD A+L+ Sbjct: 53 PEAYVT-------EPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILV 105 Query: 218 IAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADG 277 +A NE PQPQT EH A+ I+ +K++II+QNKVD++ +E AL + I +F +GT A+ Sbjct: 106 VAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAEN 165 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGV 337 PI+P+SA K NID++ E I + I P RD P ++VIRSFDVNKPG + +LKGGV Sbjct: 166 VPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGV 225 Query: 338 AGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIG 397 GGSI+ G+FK+ EI++ PG+ + +GK+ +PIF+ I S+ + K A PGGL+ Sbjct: 226 IGGSIIQGLFKVDQEIKVLPGLRV-EKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVA 284 Query: 398 VGTKVDPTLCRADRLVGQVVG-AKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKL 456 +GT +DP+L +AD L+G ++ A +P ++ +I I Y LL R++G K + KV + Sbjct: 285 IGTYLDPSLTKADNLLGSIITLADAEVPVLW-NIRIKYNLLERVVGAK----EMLKVDPI 339 Query: 457 EPNEVLMVNIGSTATGARVVAVKADMARLQLTSP-ACTEINEKIALSRRIEKHWRLIGWA 515 E LM+++GS+ T V +VK D ++L P A N + +SR+I WR+IGW Sbjct: 340 RAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWG 399 Query: 516 TIK 518 ++ Sbjct: 400 LVE 402 >5LZD-z nrPDB Length = 614 Score = 91.3 bits (225), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 72/253 (28%), Positives = 116/253 (45%), Gaps = 46/253 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 I T GHV HGK+T+++AI+GV R +E +R +TI LGYA P+PD Sbjct: 3 IATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYA----------YWPQPDGR- 51 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 PG F+D PGH+ +S ML+G +D ALL++A ++ Sbjct: 52 ----------------VPG---------FIDVPGHEKFLSNMLAGVGGIDHALLVVACDD 86 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 QT EHLA +++ + + K D + E E ++ + + +R A + Sbjct: 87 GV-MAQTREHLAILQLTGNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFI 145 Query: 283 ISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSI 342 +A +DA+ E +++ +P S RL + R+F V G V G+ Sbjct: 146 TAATEGRGMDALREHLLQ-LPEREHASQHSFRLAIDRAFTVKGAGL--------VVTGTA 196 Query: 343 LNGVFKLGDEIEI 355 L+G K+GD + + Sbjct: 197 LSGEVKVGDSLWL 209 >5IZL-A nrPDB Length = 616 Score = 90.1 bits (222), Expect = 2e-18, Method: Compositional matrix adjust. Identities = 81/291 (27%), Positives = 139/291 (47%), Gaps = 48/291 (16%) Query: 87 LNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDE----LERNITIKLGY 142 L P + + R+ +N+G +GH+ GK+ + RA+S + D+ ER IT+ LG+ Sbjct: 14 LVPRGSHMAGRRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGF 73 Query: 143 ANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMS 202 + + P P RS + + +P+ + + + V+ VDCPGH L+ Sbjct: 74 SCFSV--------PLPARLRSSLPEFQAAPEAEP----EPGEPLLQVTLVDCPGHASLIR 121 Query: 203 TMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM----REES 258 T++ GA ++D +L+I + Q Q++E L +I K V++L NK+DL+ R+ + Sbjct: 122 TIIGGAQIIDLMMLVIDVTKGM-QTQSAECLVIGQIACQKLVVVL-NKIDLLPEGKRQAA 179 Query: 259 ALEHQKSILKFIRGTIADGAPIVPISA----------QLKYNIDAVNEFIVKTIPVPPRD 308 + K + K + T GAPI+P++A + I + E + I +P RD Sbjct: 180 IDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRD 239 Query: 309 ----FMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI 355 F++S V F + +G V G+IL+G LGD +EI Sbjct: 240 PSGPFLMS----VDHCFSIKG--------QGTVMTGTILSGSISLGDSVEI 278 >4V5G-AZ nrPDB Length = 406 Score = 85.9 bits (211), Expect = 4e-17, Method: Compositional matrix adjust. Identities = 82/309 (26%), Positives = 128/309 (41%), Gaps = 101/309 (32%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAISGVQT-----VRFKD---------ELERNIT 137 E + + +N+GTIGHV HGK+T+ A++ V V KD E R IT Sbjct: 4 GEFVRTKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVEVKDYGDIDKAPEERARGIT 63 Query: 138 IKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGH 197 I + + K RH S VDCPGH Sbjct: 64 INTAHVEYETAK-------------------------------------RHYSHVDCPGH 86 Query: 198 DILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREE 257 + M++GAA MD A+L+++ + P PQT EH+ + + ++++ NKVD++ + Sbjct: 87 ADYIKNMITGAAQMDGAILVVSAADG-PMPQTREHILLARQVGVPYIVVFMNKVDMVDDP 145 Query: 258 SALEHQKSILKFIRGTI---ADGAPIVPISA-----QLKYN-----------------ID 292 L+ + ++ + D P++ SA Q+ N +D Sbjct: 146 ELLDLVEMEVRDLLNQYEFPGDEVPVIRGSALLALEQMHRNPKTRRGENEWVDKIWELLD 205 Query: 293 AVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPG-AEIEDL-----KGGVAGGSILNGV 346 A++E+ IP P R DV+KP +ED+ +G VA G I G Sbjct: 206 AIDEY----IPTPVR--------------DVDKPFLMPVEDVFTITGRGTVATGRIERGK 247 Query: 347 FKLGDEIEI 355 K+GDE+EI Sbjct: 248 VKVGDEVEI 256 >1D2E-A nrPDB Length = 397 Score = 84.7 bits (208), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 79/274 (28%), Positives = 121/274 (44%), Gaps = 58/274 (21%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 +N+GTIGHV HGK+T+ AI+ I + G A K Y+ + PE Sbjct: 4 VNVGTIGHVDHGKTTLTAAIT-------------KILAEGGGAKFKKYE-EIDNAPEERA 49 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 + + RH + DCPGH + M++G A +D +L++A Sbjct: 50 RGITINAAHVEYSTA----------ARHYAHTDCPGHADYVKNMITGTAPLDGCILVVAA 99 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDL-----MREESALEHQKSILKFIRGTIA 275 N+ P PQT EHL + ++HV++ NK D M E LE ++ + +F G Sbjct: 100 NDG-PMPQTREHLLLARQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEF--GYKG 156 Query: 276 DGAPIVPISA--------------QLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSF 321 + PI+ SA ++ +DAV+ + IPVP RD P L+ + S Sbjct: 157 EETPIIVGSALCALEQRDPELGLKSVQKLLDAVDTY----IPVPTRDLE-KPFLLPVESV 211 Query: 322 DVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI 355 + PG +G V G++ G+ K GDE E Sbjct: 212 -YSIPG------RGTVVTGTLERGILKKGDECEF 238 >5W7Q-A nrPDB Length = 373 Score = 83.6 bits (205), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 77/271 (28%), Positives = 125/271 (46%), Gaps = 54/271 (19%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 +NIGTIGHV HGK+T+ AI+ + K G A AK Y Q PE Sbjct: 6 VNIGTIGHVDHGKTTLTAAIT-------------TVLAKKGGAEAKAYD-QIDNAPEEKA 51 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 + + + + RH + VDCPGH + M++GAA MD A+L+++ Sbjct: 52 RGITINTAHVEYETEN----------RHYAHVDCPGHADYVKNMITGAAQMDGAILVVSA 101 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADG 277 + P PQT EH+ + + ++++ NK D++ +E LE + ++ + D Sbjct: 102 ADG-PMPQTREHILLARQVGVPYIVVFLNKCDMVDDEELLELVEMEVRELLSEYDFPGDD 160 Query: 278 APIVPISA------------QLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRS-FDVN 324 PI+ SA ++ +DAV+ + IP P RD + P L+ I F ++ Sbjct: 161 IPIIRGSALKALEGDAEWEDKILELMDAVDSY----IPTPERD-IDKPFLMPIEDVFSIS 215 Query: 325 KPGAEIEDLKGGVAGGSILNGVFKLGDEIEI 355 +G V G + G+ K+G+E+EI Sbjct: 216 G--------RGTVVTGRVERGIVKVGEEVEI 238 >3MMP-A nrPDB Length = 678 Score = 81.3 bits (199), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 90/307 (29%), Positives = 135/307 (43%), Gaps = 56/307 (18%) Query: 69 FEEGGGLPEQPLNPDF-------SKLNPLSAEIINR-QATINIGTIGHVAHGKSTVVRAI 120 FE G G+ + + DF SK + +S E R + +N+GTIGHV HGK+T+ AI Sbjct: 259 FEVGEGI--EKVETDFAAEVAAMSKQSHMSKEKFERTKPHVNVGTIGHVDHGKTTLTAAI 316 Query: 121 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP 180 + V + Y A Q PE R I+ P Sbjct: 317 TTV--------------LAKTYGGAARAFDQIDNAPEEKA-RGIT----INTSHVEYDTP 357 Query: 181 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK 240 RH + VDCPGH + M++GAA MD A+L++A + P PQT EH+ + Sbjct: 358 -----TRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDG-PMPQTREHILLGRQVG 411 Query: 241 LKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADGAPIVPISAQLKYNIDAVNE- 296 + ++I+ NK D++ +E LE + ++ + D PIV SA DA E Sbjct: 412 VPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEA 471 Query: 297 -------FIVKTIPVPPRDFMISPRLIVIRS-FDVNKPGAEIEDLKGGVAGGSILNGVFK 348 F+ IP P R + P L+ I F ++ +G V G + G+ K Sbjct: 472 KILELAGFLDSYIPEPERA-IDKPFLLPIEDVFSISG--------RGTVVTGRVERGIIK 522 Query: 349 LGDEIEI 355 +G+E+EI Sbjct: 523 VGEEVEI 529 >5W76-A nrPDB Length = 385 Score = 80.1 bits (196), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 73/262 (27%), Positives = 120/262 (45%), Gaps = 37/262 (14%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 +NIGTIGHV HGK+T+ AI+ V + G A K Y Q PE Sbjct: 5 VNIGTIGHVDHGKTTLTAAITKVLAEK-------------GQAEFKAYD-QIDKAPEEKE 50 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 S + + + RH + VDCPGH + M++GAA MD A+L+++ Sbjct: 51 RGITISTAHVEYETEN----------RHYAHVDCPGHADYVKNMITGAAQMDGAILVVSA 100 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADG 277 + P PQT EH+ + + ++++ NKVD++ +E LE + ++ + + D Sbjct: 101 ADG-PMPQTREHILLARQVGVPYIVVFLNKVDMVDDEELLELVEMEVRELLSSYDFPGDD 159 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDL---- 333 PI+ SA D E + + ++ P + + F + IED+ Sbjct: 160 IPIIKGSALKALEGDEEGEEAIMKLMDAVDSYIPEPERAIDKPFLM-----PIEDVFSIS 214 Query: 334 KGGVAGGSILNGVFKLGDEIEI 355 +G V G + G+ K+G+E+EI Sbjct: 215 RGTVVTGRVERGIVKVGEEVEI 236 >1EFM-A nrPDB Length = 379 Score = 79.7 bits (195), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 78/267 (29%), Positives = 117/267 (43%), Gaps = 60/267 (22%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 +N+GTIGHV HGK+T+ AI+ V + R ITI N + PT Sbjct: 12 VNVGTIGHVDHGKTTLTAAITTVLAKTYGGA-ARGITI-----NTSHVEYDTPT------ 59 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 RH + VDCPGH + M++GAA MD A+L++A Sbjct: 60 --------------------------RHYAHVDCPGHADYVKNMITGAAQMDGAILVVAA 93 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADG 277 + P PQT EH+ + + ++I+ NK D++ +E LE + ++ + D Sbjct: 94 TDG-PMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDD 152 Query: 278 APIVPISAQLKYNIDAVNE--------FIVKTIPVPPRDFMISPRLIVIRS-FDVNKPGA 328 PIV SA DA E F+ IP P R + P L+ I F ++ Sbjct: 153 TPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERA-IDKPFLLPIEDVFSISG--- 208 Query: 329 EIEDLKGGVAGGSILNGVFKLGDEIEI 355 +G V G + G+ K+G+E+EI Sbjct: 209 -----RGTVVTGRVERGIIKVGEEVEI 230 >1MJ1-A nrPDB Length = 405 Score = 77.4 bits (189), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 72/297 (24%), Positives = 126/297 (42%), Gaps = 77/297 (25%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQ 151 E I + +N+GTIGHV HGK+T+ A++ V RN+ +K Y + I K + Sbjct: 3 GEFIRTKRHVNVGTIGHVDHGKTTLTAALTYVAAAE-----NRNVEVK-DYGD--IDKAR 54 Query: 152 EPTCPE---PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGA 208 E + +++ K RH S VDC GH + M++GA Sbjct: 55 EERARGITINTAHVEYETAK------------------RHYSHVDCRGHADYIKNMITGA 96 Query: 209 AVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESAL-------- 260 A MD A+L+++ + QT EH+ + ++++++ NKVD++ + L Sbjct: 97 AQMDGAILVVSAADG-RMRQTREHILLARQVGVRYIVVFMNKVDMVDDRELLDLVEMEVR 155 Query: 261 ------EHQKSILKFIRGTIADGAPIVPISAQLKYN-----------IDAVNEFIVKTIP 303 E + ++ IRG+ + + + K +DA++E+I + Sbjct: 156 DLLNQYEFRGDEVRVIRGSALLALEEMHKNRKTKRGENEWVDKIWELLDAIDEYIRTRVR 215 Query: 304 VPPRDFMISPRLIVIRSFDVNKPGAEIEDL-----KGGVAGGSILNGVFKLGDEIEI 355 + F++ +ED+ +G VA G I G K+GDE+EI Sbjct: 216 DVDKRFLMR-----------------VEDVFTITGRGTVATGRIERGKVKVGDEVEI 255 >5W75-A nrPDB Length = 392 Score = 75.9 bits (185), Expect = 4e-14, Method: Compositional matrix adjust. Identities = 74/280 (26%), Positives = 122/280 (43%), Gaps = 68/280 (24%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 +N+GTIGHV HGKST+ AI+ +++ G A Y Q PE Sbjct: 5 VNVGTIGHVDHGKSTLTAAITKYLSLK-------------GLAQYVPYD-QIDKAPEEKA 50 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 + + + ++ RH + +DCPGH + M++GAA MD A+L++A Sbjct: 51 RGITINITHVEYETEK----------RHYAHIDCPGHADYIKNMITGAAQMDGAILVVAA 100 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADG 277 + P PQT EH+ + + ++I+ NK D++ + +E + ++ + D Sbjct: 101 TDG-PMPQTREHVLLARQVGVPYMIVFINKTDMVDDPELIELVEMEVRDLLSQYEYPGDE 159 Query: 278 APIVPISA----------------QLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSF 321 P++ SA ++ +DA++ + IP P R Sbjct: 160 VPVIKGSALKALEAPDDPNHEAYKPIQELLDAMDNY----IPDPQR-------------- 201 Query: 322 DVNKPG-AEIEDL-----KGGVAGGSILNGVFKLGDEIEI 355 DV+KP IED+ +G V G I G + GDE+EI Sbjct: 202 DVDKPFLMPIEDVFSITGRGTVVTGRIERGRIRPGDEVEI 241 >4AC9-A nrPDB Length = 482 Score = 75.1 bits (183), Expect = 8e-14, Method: Compositional matrix adjust. Identities = 61/265 (23%), Positives = 123/265 (46%), Gaps = 56/265 (21%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDEL----ERNITIKLGYANAKIYKCQEPTCP 156 IN+G GH+ HGK+T+ + ++ + + D+L +R ITI +G++ K+ Sbjct: 20 INLGIFGHIDHGKTTLSKVLTEIASTSAHDKLPESQKRGITIDIGFSAFKL--------- 70 Query: 157 EPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALL 216 + YR ++ VD PGH L+ ++S A ++D AL+ Sbjct: 71 --ENYR--------------------------ITLVDAPGHADLIRAVVSAADIIDLALI 102 Query: 217 LIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIAD 276 ++ E P+ QT EH+ ++ + ++++ + EE ++ + I+K I + + Sbjct: 103 VVDAKEG-PKTQTGEHMLILDHFNIPIIVVITKSDNAGTEE--IKRTEMIMKSILQSTHN 159 Query: 277 --GAPIVPISAQLKYNIDAVNEFIVKTIPVPP--RDFMISPRLIVIRSFDVNKPGAEIED 332 + I+PISA+ + +D + I+ T+ R+ ++ + +F + G Sbjct: 160 LKNSSIIPISAKTGFGVDELKNLIITTLNNAEIIRNTESYFKMPLDHAFPIKGAGT---- 215 Query: 333 LKGGVAGGSILNGVFKLGDEIEIRP 357 V G+I G+ K+GDE+++ P Sbjct: 216 ----VVTGTINKGIVKVGDELKVLP 236 >6MIJ-A nrPDB Length = 396 Score = 73.9 bits (180), Expect = 1e-13, Method: Compositional matrix adjust. Identities = 75/265 (28%), Positives = 122/265 (46%), Gaps = 40/265 (15%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 +N+GTIGHV HGK+T+ AI+ + + E AK Y Q + PE Sbjct: 13 VNVGTIGHVDHGKTTLTAAIATICAKTYGGE-------------AKDYS-QIDSAPEEKA 58 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 + + + P RH + VDCPGH + M++GAA MD A+L+ A Sbjct: 59 RGITINTSHV--EYDSP--------TRHYAHVDCPGHADYVKNMITGAAQMDGAILVCAA 108 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADG 277 + P PQT EH+ + + ++I+ NK DL+ +E LE + ++ + T D Sbjct: 109 TDG-PMPQTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELLSTYDFPGDD 167 Query: 278 APIVPISAQLKYNIDA--VNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDL-- 333 P++ SA N +A E V + ++ P + ++F + IED+ Sbjct: 168 TPVIRGSALAALNGEAGPYGEESVLALVAALDSYIPEPERAIDKAFLM-----PIEDVFS 222 Query: 334 ---KGGVAGGSILNGVFKLGDEIEI 355 +G V G + G+ K+G+E+EI Sbjct: 223 ISGRGTVVTGRVEAGIIKVGEEVEI 247 >4J0Q-A nrPDB Length = 433 Score = 73.9 bits (180), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 76/283 (26%), Positives = 120/283 (42%), Gaps = 75/283 (26%) Query: 101 INIGTIGHVAHGKSTVVRAIS-------GVQTVRFK------DELERNITIKLGYANAKI 147 +N+GTIGHV HGK+T+ A++ G V F +E R ITI + Sbjct: 49 VNVGTIGHVDHGKTTLTAALTRVCSEVFGSAIVEFDKIDSAPEEKARGITINTAHVE--- 105 Query: 148 YKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 Y S +RH + VDCPGH + M++G Sbjct: 106 -------------YNS---------------------TIRHYAHVDCPGHADYVKNMITG 131 Query: 208 AAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSIL 267 AA MD A+L+ + + P PQT EH+ + + ++++ NK DL+ + LE + + Sbjct: 132 AAQMDGAILVCSAADG-PMPQTREHILLSRQVGVPYIVVFLNKADLVDDAELLELVEMEV 190 Query: 268 KFIRGTI---ADGAPIVPISAQLKYNIDAVNEF-------IVKT----IPVPPRDFMISP 313 + + T D PI+ SA++ NE +V+T IP P R + P Sbjct: 191 RDLLSTYDFPGDDTPIIIGSARMALEGKDDNEMGTTAVKKLVETLDSYIPEPVRA-IDQP 249 Query: 314 RLIVIRS-FDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI 355 L+ I F ++ +G V G I G+ ++ D +EI Sbjct: 250 FLMPIEDVFSISG--------RGTVVTGRIERGIVRVQDPLEI 284 >4ZV4-A nrPDB Length = 405 Score = 73.2 bits (178), Expect = 3e-13, Method: Compositional matrix adjust. Identities = 74/283 (26%), Positives = 121/283 (42%), Gaps = 75/283 (26%) Query: 101 INIGTIGHVAHGKSTVVRAISGV------QTVRFKDELE-------RNITIKLGYANAKI 147 +N+GTIGHV HGK+T+ A++ V + R D+++ R ITI + Sbjct: 13 VNVGTIGHVDHGKTTLTAALTKVCSDTWGGSARAFDQIDNAPEEKARGITINTSHVE--- 69 Query: 148 YKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 Y S VRH + VDCPGH + M++G Sbjct: 70 -------------YDS---------------------AVRHYAHVDCPGHADYVKNMITG 95 Query: 208 AAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSIL 267 AA MD A+L+ + + P PQT EH+ + + ++++ NK D++ + LE + + Sbjct: 96 AAQMDGAILVCSAADG-PMPQTREHILLSRQVGVPYIVVFLNKADMVDDAELLELVEMEV 154 Query: 268 KFIRGTI---ADGAPIVPISAQLKY--------NIDAVN---EFIVKTIPVPPRDFMISP 313 + + T D PI+ SA + + AV E + IP P R + P Sbjct: 155 RDLLNTYDFPGDDTPIIIGSALMALEGKDDNGIGVSAVQKLVETLDSYIPEPVRA-IDQP 213 Query: 314 RLIVIRS-FDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI 355 L+ I F ++ +G V G + G+ K+ +E+EI Sbjct: 214 FLMPIEDVFSISG--------RGTVVTGRVERGIIKVQEEVEI 248 >2HDN-B nrPDB Length = 335 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 57/181 (31%), Positives = 89/181 (49%), Gaps = 22/181 (12%) Query: 187 RHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVII 246 RH + VDCPGH + M++GAA MD A+L++A + P PQT EH+ + + ++I+ Sbjct: 16 RHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDG-PMPQTREHILLGRQVGVPYIIV 74 Query: 247 LQNKVDLMREESALEHQKSILKFIRGTI---ADGAPIVPISAQLKYNIDAVNE------- 296 NK D++ +E LE + ++ + D PIV SA DA E Sbjct: 75 FLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELA 134 Query: 297 -FIVKTIPVPPRDFMISPRLIVIRS-FDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIE 354 F+ IP P R + P L+ I F ++ +G V G + G+ K+G+E+E Sbjct: 135 GFLDSYIPEPERA-IDKPFLLPIEDVFSISG--------RGTVVTGRVERGIIKVGEEVE 185 Query: 355 I 355 I Sbjct: 186 I 186 >4ZU9-A nrPDB Length = 582 Score = 65.1 bits (157), Expect = 8e-11, Method: Compositional matrix adjust. Identities = 64/273 (23%), Positives = 115/273 (42%), Gaps = 65/273 (23%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 I T GHV HGK+T+++ ++G+ T R +E +R ++I +G+A Sbjct: 4 ILFATAGHVDHGKTTLIKTLTGIDTDRLPEEKKRGLSIDIGFA----------------- 46 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 Y F P R + +D PGH+ + ++G +L++ Sbjct: 47 YIDF------------PDINTR------LEIIDVPGHERFIKNAIAGICSASGLILVVDP 88 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESA----------LEHQKSILKFI 270 NE PQT EHL + +KH I + K+D + EE A LE ++ ++ + Sbjct: 89 NEGI-MPQTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAEEELIAFLEKEEMNMEIV 147 Query: 271 RGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEI 330 + + G I + +K ++++N P R F+ S V++ + Sbjct: 148 KVSAVTGQGIEDLKNSIKKLLESINNL---NKHKPLRIFVDSA--FVVKGY--------- 193 Query: 331 EDLKGGVAGGSILNGVFKLGDEIEIRP-GIVTK 362 G V GS G K GD++ + P G++++ Sbjct: 194 ----GTVLRGSCFEGEVKEGDKVVVEPIGVISR 222 >3WY9-A nrPDB Length = 434 Score = 61.6 bits (148), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 87/349 (24%), Positives = 151/349 (43%), Gaps = 63/349 (18%) Query: 101 INIGTIGHVAHGKSTVV-RAISGVQTV------RFKDELERNITIKLGYANAKIYKCQEP 153 +NI IGHV HGKST + R + + +F++ E+ + K + ++ + +E Sbjct: 8 VNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFEEMGEKGKSFKFAWVMDRLKEERER 67 Query: 154 TCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDA 213 + F++ P RY ++ +D PGH + M++GA+ DA Sbjct: 68 GITIDVAHTKFET-------------PHRY-----ITIIDAPGHRDFVKNMITGASQADA 109 Query: 214 ALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKS-ILKFIR 271 A+L++A + PQT EH + +KH+I+ NK+D++ ++ E K+ + K ++ Sbjct: 110 AVLVVAATDGV-MPQTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKAQVEKLLK 168 Query: 272 GTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFD--------V 323 P++P SA +N D V + K+ +P + P L I + D + Sbjct: 169 TLGYKDFPVIPTSA---WNGDNV---VKKSDKMP---WYNGPTL--IEALDQIPEPEKPI 217 Query: 324 NKP-GAEIEDLK-----GGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNI 377 +KP I+D+ G V G + G K+GD + P I KPI + Sbjct: 218 DKPLRIPIQDVYSIKGVGTVPVGRVETGKLKVGDVVIFEPA-------STIFHKPIQGEV 270 Query: 378 VSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNI 426 S+ L+ A+PG IG + + + D G V G P + Sbjct: 271 KSIEMHHEPLQEALPGDNIGFNVR---GVSKNDIKRGDVAGHTDKPPTV 316 >3WXM-A nrPDB Length = 447 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 89/394 (22%), Positives = 153/394 (38%), Gaps = 124/394 (31%) Query: 101 INIGTIGHVAHGKSTVVRAI---------------------SGVQTVRF-------KDEL 132 +N+ IGHV HGKST+V + G ++ +F K+E Sbjct: 10 MNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESFKFAWILDKMKEER 69 Query: 133 ERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFV 192 ER ITI L + F++ K + + + Sbjct: 70 ERGITIDL-------------------TFMKFETKKYV------------------FTII 92 Query: 193 DCPGHDILMSTMLSGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVII 246 D PGH + M++GA+ DAA+L+++ + + QT EHL M ++ +I+ Sbjct: 93 DAPGHRDFVKNMITGASQADAAILVVSARKGEFEAGMSTEGQTREHLLLARTMGIEQIIV 152 Query: 247 LQNKV---DLMREESALEHQKSIL-KFIR--GTIADGAPIVPISAQL------------K 288 NK+ D+ ++ E S+L KF++ G D P +P+SA Sbjct: 153 AVNKMDAPDVNYDQKRYEFVVSVLKKFMKGLGYQVDKIPFIPVSAWKGDNLIERSPNMPW 212 Query: 289 YN----IDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILN 344 YN ++A+++ PP + P I +++ + PGA G V G + Sbjct: 213 YNGPTLVEALDQL------QPPAKPVDKPLRIPVQNV-YSIPGA------GTVPVGRVET 259 Query: 345 GVFKLGDEIEIR-PGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVD 403 GV ++GD++ PG+V + S+ L+ A PG IG + Sbjct: 260 GVLRVGDKVVFMPPGVV--------------GEVRSIEMHYQQLQQAEPGDNIGFAVR-- 303 Query: 404 PTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLL 437 + ++D G V G P + + E F++ Sbjct: 304 -GVSKSDIKRGDVAGHLDKPPTVAEEFEARIFVI 336 >1JNY-A nrPDB Length = 435 Score = 58.9 bits (141), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 81/365 (22%), Positives = 149/365 (40%), Gaps = 76/365 (20%) Query: 95 INRQATINIGTIGHVAHGKSTVV------RAISGVQTVRFKDELERNI---TIKLGYANA 145 ++++ +N+ IGHV HGKST+V R +TV+ +E + + + K + Sbjct: 1 MSQKPHLNLIVIGHVDHGKSTLVGRLLMDRGFIDEKTVKEAEEAAKKLGKESEKFAFLLD 60 Query: 146 KIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTML 205 ++ + +E + F++ K + +D PGH + M+ Sbjct: 61 RLKEERERGVTINLTFMRFETKKYF------------------FTIIDAPGHRDFVKNMI 102 Query: 206 SGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESA 259 +GA+ DAA+L+++ + + QT EH+ + M L +I+ NK+DL Sbjct: 103 TGASQADAAILVVSAKKGEYEAGMSVEGQTREHIILAKTMGLDQLIVAVNKMDLTEPPYD 162 Query: 260 LEHQKSIL----KFIR--GTIADGAPIVPI-----------SAQLK-YNIDAVNEFIVKT 301 + K I+ KF+R G + VP+ S +K YN + E++ Sbjct: 163 EKRYKEIVDQVSKFMRSYGFNTNKVRFVPVVAPSGDNITHKSENMKWYNGPTLEEYL-DQ 221 Query: 302 IPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVT 361 + +PP+ R+ + + ++ G V G + +GV K+GD+I P Sbjct: 222 LELPPKPVDKPLRIPIQDVYSISGVGT--------VPVGRVESGVLKVGDKIVFMPA--- 270 Query: 362 KDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKG 421 GK+ + S+ + A PG IG + + + D G VVG Sbjct: 271 ----GKV------GEVRSIETHHTKMDKAEPGDNIGFNVR---GVEKKDIKRGDVVGHPN 317 Query: 422 HLPNI 426 + P + Sbjct: 318 NPPTV 322 >1ZUN-B nrPDB Length = 434 Score = 48.5 bits (114), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 101/246 (41%), Gaps = 45/246 (18%) Query: 187 RHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVII 246 R D PGH+ M +GA+ D A++L+ Q QT H ++ +KH+++ Sbjct: 104 RKFIIADTPGHEQYTRNMATGASTCDLAIILVDARYGV-QTQTRRHSYIASLLGIKHIVV 162 Query: 247 LQNKVDLM-REESALEHQKS-ILKFIRG------TIADGAPIVPISAQLKYNIDAVNEF- 297 NK+DL +E E K+ LKF G T+A VP+SA N+ +E Sbjct: 163 AINKMDLNGFDERVFESIKADYLKFAEGIAFKPTTMA----FVPMSALKGDNVVNKSERS 218 Query: 298 ----------IVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVF 347 I++T+ + R V VN+P G +A +G+ Sbjct: 219 PWYAGQSLMEILETVEIASDRNYTDLRFPVQY---VNRPNLNFRGFAGTLA-----SGIV 270 Query: 348 KLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLC 407 GDEI + P GK S + S+ + +L+ A PG + + + + + Sbjct: 271 HKGDEIVVLP-------SGK------SSRVKSIVTFEGELEQAGPGQAVTLTMEDEIDIS 317 Query: 408 RADRLV 413 R D LV Sbjct: 318 RGDLLV 323 >5LZT-jj nrPDB Length = 637 Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 44/168 (26%), Positives = 75/168 (44%), Gaps = 27/168 (16%) Query: 97 RQATINIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIK---LGYANAKIYKC 150 ++ +N+ IGHV GKST+ + ++G+ R ++ ER K Y + + Sbjct: 209 KKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTN 268 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 QE + DK + + R K H + +D PGH + M+ GA+ Sbjct: 269 QE------------ERDKGKTVEVGRAYFETEKK---HFTILDAPGHKSFVPNMIGGASQ 313 Query: 211 MDAALLLIAGNESCPQP------QTSEHLAAIEIMKLKHVIILQNKVD 252 D A+L+I+ + + QT EH + +KH+I+L NK+D Sbjct: 314 ADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMD 361 >4D61-i nrPDB Length = 426 Score = 46.6 bits (109), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 27/164 (16%) Query: 101 INIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIK---LGYANAKIYKCQEPT 154 +N+ IGHV GKST+ + ++G+ R ++ ER K Y + + QE Sbjct: 4 VNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQE-- 61 Query: 155 CPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAA 214 + DK + + R K H + +D PGH + M+ GA+ D A Sbjct: 62 ----------ERDKGKTVEVGRAYFETEKK---HFTILDAPGHKSFVPNMIGGASQADLA 108 Query: 215 LLLIAGNESCPQP------QTSEHLAAIEIMKLKHVIILQNKVD 252 +L+I+ + + QT EH + +KH+I+L NK+D Sbjct: 109 VLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMD 152 >2B7C-A nrPDB Length = 458 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 54/202 (26%), Positives = 88/202 (43%), Gaps = 27/202 (13%) Query: 98 QATINIGTIGHVAHGKST----VVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEP 153 ++ IN+ IGHV GKST ++ G+ R ++ E+ +LG + K + Sbjct: 5 KSHINVVVIGHVDSGKSTTTGHLIYKCGGIDK-RTIEKFEKEAA-ELGKGSFKYAWVLDK 62 Query: 154 TCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDA 213 E + R D + K + P +Y+ V+ +D PGH + M++G + D Sbjct: 63 LKAERE--RGITIDIALW-KFETP----KYQ----VTVIDAPGHRDFIKNMITGTSQADC 111 Query: 214 ALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR--EESALEHQKS 265 A+L+IAG QT EH + ++ +I+ NK+D ++ E E K Sbjct: 112 AILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEIVKE 171 Query: 266 ILKFIR--GTIADGAPIVPISA 285 FI+ G P VPIS Sbjct: 172 TSNFIKKVGYNPKTVPFVPISG 193 >3J4J-A nrPDB Length = 569 Score = 45.4 bits (106), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 27/213 (12%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQ 248 V F+D PGH+ + GA V D A+++IA ++ PQT E +A + K + + Sbjct: 122 VVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGI-MPQTEEAIAHAKAAGAKLIFAI- 179 Query: 249 NKVDLMREE-SALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR 307 NK+DL + + ++ Q F+ A ++PISA+ + + E I+ + Sbjct: 180 NKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEMILLLAELEDY 239 Query: 308 --DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDK 365 D PR +++ S +++ G +A + G F++GD +V + Sbjct: 240 RADPNAEPRGVILES--------KLDKQAGIIANMLVQEGTFRVGDY------VVAGEAY 285 Query: 366 GKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV 398 G+I+ + A+ N K A PG + V Sbjct: 286 GRIRA--------MMDADGNQRKEAGPGSAVQV 310 >4KJZ-A nrPDB Length = 473 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 27/213 (12%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQ 248 V F+D PGH+ + GA V D A+++IA ++ PQT E +A + K + + Sbjct: 121 VVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGI-MPQTEEAIAHAKAAGAKLIFAI- 178 Query: 249 NKVDLMREE-SALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR 307 NK+DL + + ++ Q F+ A ++PISA+ + + E I+ + Sbjct: 179 NKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEMILLLAELEDY 238 Query: 308 --DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDK 365 D PR +++ S +++ G +A + G F++GD +V + Sbjct: 239 RADPNAEPRGVILES--------KLDKQAGIIANMLVQEGTFRVGDY------VVAGEAY 284 Query: 366 GKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV 398 G+I+ + A+ N K A PG + V Sbjct: 285 GRIRA--------MMDADGNQRKEAGPGSAVQV 309 >4B44-A nrPDB Length = 363 Score = 45.1 bits (105), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 52/213 (24%), Positives = 94/213 (44%), Gaps = 27/213 (12%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQ 248 V F+D PGH+ + GA V D A+++IA ++ PQT E +A + K + + Sbjct: 122 VVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGI-MPQTEEAIAHAKAAGAKLIFAI- 179 Query: 249 NKVDLMREE-SALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR 307 NK+DL + + ++ Q F+ A ++PISA+ + + E I+ + Sbjct: 180 NKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEMILLLAELEDY 239 Query: 308 --DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDK 365 D PR +++ S +++ G +A + G F++GD +V + Sbjct: 240 RADPNAEPRGVILES--------KLDKQAGIIANMLVQEGTFRVGDY------VVAGEAY 285 Query: 366 GKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV 398 G+I+ + A+ N K A PG + V Sbjct: 286 GRIRA--------MMDADGNQRKEAGPGSAVQV 310 >1G7S-A nrPDB Length = 594 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 40/150 (26%), Positives = 63/150 (42%), Gaps = 24/150 (16%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK+T++ I G + IT +G + E C D + Sbjct: 8 VSVLGHVDHGKTTLLDHIRGSAVASRE---AGGITQHIGATEIPM-DVIEGICG--DFLK 61 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 F R PG + F+D PGH+ + G A+ D A+L++ NE Sbjct: 62 KF---------SIRETLPGLF-------FIDTPGHEAFTTLRKRGGALADLAILIVDINE 105 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVD 252 +PQT E L + + + V + NK+D Sbjct: 106 GF-KPQTQEALNILRMYRTPFV-VAANKID 133 >3MCA-A nrPDB Length = 592 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/104 (28%), Positives = 51/104 (49%), Gaps = 11/104 (10%) Query: 193 DCPGHDILMSTMLSGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVII 246 D PGH +S M++GA+ D A+L++ +++ QT EH + + + +++ Sbjct: 261 DAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLENGQTREHAYLLRALGISEIVV 320 Query: 247 LQNKVDLMR-EESALEHQKSILK--FIR--GTIADGAPIVPISA 285 NK+DLM E + K+I+ I+ G VPISA Sbjct: 321 SVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKTSNVHFVPISA 364 >1R5O-A nrPDB Length = 467 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 39/161 (24%), Positives = 72/161 (44%), Gaps = 21/161 (13%) Query: 101 INIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE 157 +NI IGHV GKST+ + ++G+ R +++ER + G + + + T E Sbjct: 44 VNIVFIGHVDAGKSTLGGNILFLTGMVDKRTMEKIEREAK-EAGKESWYLSWALDSTSEE 102 Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLL 217 +K + + R + R S +D PGH ++ M++GA+ D +L+ Sbjct: 103 --------REKGKTVEVGRAYFETEH---RRFSLLDAPGHKGYVTNMINGASQADIGVLV 151 Query: 218 IAGNESCPQP------QTSEHLAAIEIMKLKHVIILQNKVD 252 I+ + QT EH + H++++ NK+D Sbjct: 152 ISARRGEFEAGFERGGQTREHAVLARTQGINHLVVVINKMD 192 >5LZS-jj nrPDB Length = 462 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 29/110 (26%), Positives = 50/110 (45%), Gaps = 12/110 (10%) Query: 188 HVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKL 241 +V+ +D PGH + M++G + D A+L++A QT EH + + Sbjct: 86 YVTIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGV 145 Query: 242 KHVIILQNKVDLMREESALEHQKSILK----FIR--GTIADGAPIVPISA 285 K +I+ NK+D + + + I+K +I+ G D VPIS Sbjct: 146 KQLIVGVNKMDSTEPPYSQKRYEEIVKEVSTYIKKIGYNPDTVAFVPISG 195 >4C0S-A nrPDB Length = 463 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/116 (24%), Positives = 49/116 (42%), Gaps = 12/116 (10%) Query: 188 HVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKL 241 +++ +D PGH + M++G + D A+L++A QT EH + + Sbjct: 86 YITIIDAPGHRDFIKNMITGTSQADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGV 145 Query: 242 KHVIILQNKVDLMREESALEHQKSILKFIRGTIAD------GAPIVPISAQLKYNI 291 K +I+ NK+D + + I+K + I P VPIS N+ Sbjct: 146 KQLIVGVNKMDSTEPAYSEKRYDEIVKEVSAYIKKIGYNPATVPFVPISGWHGDNM 201 >5FG3-A nrPDB Length = 623 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 6/64 (9%) Query: 191 FVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHV--IILQ 248 F+D PGH++ + G +V D A+L++ E +PQT E A+E++K + V +I Sbjct: 85 FIDTPGHELFSNLRRRGGSVADFAILVVDIMEGF-KPQTYE---ALELLKERRVPFLIAA 140 Query: 249 NKVD 252 NK+D Sbjct: 141 NKID 144 >5YT0-A nrPDB Length = 364 Score = 39.7 bits (91), Expect = 0.004, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 6/64 (9%) Query: 191 FVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHV--IILQ 248 F+D PGH++ + G +V D A+L++ E +PQT E A+E++K + V +I Sbjct: 85 FIDTPGHELFSNLRRRGGSVADFAILVVDIMEGF-KPQTYE---ALELLKERRVPFLIAA 140 Query: 249 NKVD 252 NK+D Sbjct: 141 NKID 144 >4V6V-A1 nrPDB Length = 639 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/64 (31%), Positives = 37/64 (57%), Gaps = 2/64 (3%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQ 248 V+ +D PGH ++ + +V+D A+LL++ + Q QT A++IMK+ + + Sbjct: 70 VNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSAKDGI-QAQTRILFHALQIMKIPTIFFI- 127 Query: 249 NKVD 252 NK+D Sbjct: 128 NKID 131 >4V6W-Az nrPDB Length = 844 Score = 38.9 bits (89), Expect = 0.005, Method: Compositional matrix adjust. Identities = 53/187 (28%), Positives = 80/187 (42%), Gaps = 40/187 (21%) Query: 102 NIGTIGHVAHGKSTVVRA-------ISGVQT--VRF----KDELERNITIKLGYANAKIY 148 N+ I HV HGKST+ + I+G + RF KDE ER ITIK A + + Sbjct: 21 NMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIK-STAISMYF 79 Query: 149 KCQEPTC---PEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTML 205 + +E PD + +KE C G ++ +D PGH S + Sbjct: 80 EVEEKDLVFITHPD-----QREKE---------CKGFL-----INLIDSPGHVDFSSEVT 120 Query: 206 SGAAVMDAALLLI-AGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQK 264 + V D AL+++ + C Q +T A E +K I+ NK+D E L+ ++ Sbjct: 121 AALRVTDGALVVVDCVSGVCVQTETVLRQAIAERIK---PILFMNKMDRALLELQLDAEE 177 Query: 265 SILKFIR 271 F R Sbjct: 178 LYQTFQR 184 >2P8Y-T nrPDB Length = 842 Score = 38.9 bits (89), Expect = 0.006, Method: Compositional matrix adjust. Identities = 49/165 (29%), Positives = 75/165 (45%), Gaps = 38/165 (23%) Query: 102 NIGTIGHVAHGKSTVVRAI---SGVQT------VRF----KDELERNITIKLGYANAKIY 148 N+ I HV HGKST+ ++ +G+ + RF KDE ER ITIK +Y Sbjct: 21 NMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIK--STAISLY 78 Query: 149 KCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGA 208 S SD+++ Q+ G L ++ +D PGH S + + Sbjct: 79 --------------SEMSDEDVKEIKQK--TDGNSFL---INLIDSPGHVDFSSEVTAAL 119 Query: 209 AVMDAALLLIAGNES-CPQPQTSEHLAAIEIMKLKHVIILQNKVD 252 V D AL+++ E C Q +T A E ++K V+++ NKVD Sbjct: 120 RVTDGALVVVDTIEGVCVQTETVLRQALGE--RIKPVVVI-NKVD 161 >2LKD-A nrPDB Length = 178 Score = 37.0 bits (84), Expect = 0.021, Method: Compositional matrix adjust. Identities = 41/163 (25%), Positives = 69/163 (42%), Gaps = 48/163 (29%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQ 151 + ++ R + I +GHV HGK+T++ AI + + ++ IT +G Sbjct: 2 SHMVERPPVVTI--MGHVDHGKTTLLDAI---RHSKVTEQEAGGITQHIG---------- 46 Query: 152 EPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVM 211 Y+ +DK+I+ F+D PGH+ + GA V Sbjct: 47 --------AYQVTVNDKKIT-------------------FLDTPGHEAFTTMRARGAQVT 79 Query: 212 DAALLLIAGNESCPQPQTSEHLAAIEIMKLKHV--IILQNKVD 252 D +L++A ++ PQT E AI K +V I+ NK+D Sbjct: 80 DIVILVVAADDGV-MPQTVE---AINHAKAANVPIIVAINKMD 118 >2YWH-A nrPDB Length = 600 Score = 37.0 bits (84), Expect = 0.022, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 101/264 (38%), Gaps = 58/264 (21%) Query: 102 NIGTIGHVAHGKSTVVRAI---SGVQTVRFKDE---------LERNITIKLGYANAKIYK 149 N I HV HGKST+ + +G + R K E ER IT+K+ A YK Sbjct: 8 NFCIIAHVDHGKSTLADRLLEYTGAISEREKREQLLDTLDVERERGITVKMQ-AVRMFYK 66 Query: 150 CQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAA 209 ++ YKL +D PGH + A Sbjct: 67 AKDGNT---------------------------YKL----HLIDTPGHVDFSYEVSRALA 95 Query: 210 VMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKF 269 + ALLLI ++ + A+E + +I + NK+DL + ++ K ++ Sbjct: 96 ACEGALLLIDASQGIEAQTVANFWKAVEQDLV--IIPVINKIDL--PSADVDRVKKQIEE 151 Query: 270 IRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAE 329 + G D + SA+ I+ + E IV IP P D + ++ S+ Sbjct: 152 VLGL--DPEEAILASAKEGIGIEEILEAIVNRIPPPKGDPQKPLKALIFDSY-------- 201 Query: 330 IEDLKGGVAGGSILNGVFKLGDEI 353 + +G VA I +G K GD+I Sbjct: 202 YDPYRGAVAFVRIFDGEVKPGDKI 225 >5LZY-jj nrPDB Length = 710 Score = 35.8 bits (81), Expect = 0.052, Method: Compositional matrix adjust. Identities = 21/72 (29%), Positives = 37/72 (51%), Gaps = 10/72 (13%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLI--------AGNESCPQPQTSEHLAAIEIMK 240 ++ +D PGH + M++GAA D A+L++ AG E+ QT EH + + Sbjct: 366 ITLMDAPGHKDFIPNMITGAAQADVAVLVVDASRGEFEAGFETG--GQTREHGLLVRSLG 423 Query: 241 LKHVIILQNKVD 252 + + + NK+D Sbjct: 424 VTQLAVAVNKMD 435 >2OKJ-A nrPDB Length = 504 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 18/62 (29%), Positives = 36/62 (58%), Gaps = 1/62 (1%) Query: 434 YFLLRRLLGVKTDGQKQAKVRKLEPN-EVLMVNIGSTATGARVVAVKADMARLQLTSPAC 492 +++ + L GV Q++ K+ K+ P + LM+ G+T G + KA+ R+ +++PA Sbjct: 424 WYIPQSLRGVPDSPQRREKLHKVAPKIKALMMESGTTMVGYQPQGDKANFFRMVISNPAA 483 Query: 493 TE 494 T+ Sbjct: 484 TQ 485 >5KCS-1w nrPDB Length = 639 Score = 34.3 bits (77), Expect = 0.15, Method: Compositional matrix adjust. Identities = 20/69 (28%), Positives = 35/69 (50%), Gaps = 5/69 (7%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIIL- 247 V+ +D PGH ++ + +V+D A+LLI+ + Q QT A+ M + + + Sbjct: 70 VNIIDTPGHMDFLAEVYRSLSVLDGAILLISAKDGV-QAQTRILFHALRKMGIPTIFFIN 128 Query: 248 ---QNKVDL 253 QN +DL Sbjct: 129 KIDQNGIDL 137 >3IZQ-1 nrPDB Length = 611 Score = 33.9 bits (76), Expect = 0.17, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Query: 179 CPGRYKLVR-HVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQP------QTSE 231 C + R + + VD PGH + + G + D A+L + + + + QT E Sbjct: 236 CTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKE 295 Query: 232 HLAAIEIMKLKHVIILQNKVD-LMREESALEHQKS-ILKFIR--GTIADGAPIVPISA 285 H+ + + ++II NK+D + + E KS +L ++ G D VPIS Sbjct: 296 HMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISG 353 >3P27-A nrPDB Length = 483 Score = 33.5 bits (75), Expect = 0.22, Method: Compositional matrix adjust. Identities = 30/118 (25%), Positives = 52/118 (44%), Gaps = 11/118 (9%) Query: 179 CPGRYKLVR-HVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQP------QTSE 231 C + R + + VD PGH + + G + D A+L + + + + QT E Sbjct: 102 CTSHFSTHRANFTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDLDGQTKE 161 Query: 232 HLAAIEIMKLKHVIILQNKVD-LMREESALEHQKS-ILKFIR--GTIADGAPIVPISA 285 H+ + + ++II NK+D + + E KS +L ++ G D VPIS Sbjct: 162 HMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWVPISG 219 >3JCN-b nrPDB Length = 890 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHL 233 ++F+D PGH S GA D +L++A ++ PQT E + Sbjct: 440 ITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGV-MPQTIEAI 483 >4CRN-P nrPDB Length = 430 Score = 33.1 bits (74), Expect = 0.30, Method: Compositional matrix adjust. Identities = 16/52 (30%), Positives = 27/52 (51%), Gaps = 6/52 (11%) Query: 187 RHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQP------QTSEH 232 R + +D PGH + +S M+ GA+ D +L+I+ + + QT EH Sbjct: 83 RRYTILDAPGHKMYVSEMIGGASQADVGVLVISARKGEYETGFERGGQTREH 134 >1ZO1-I nrPDB Length = 501 Score = 32.7 bits (73), Expect = 0.38, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 24/45 (53%), Gaps = 1/45 (2%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHL 233 ++F+D PGH S GA D +L++A ++ PQT E + Sbjct: 53 ITFLDTPGHAAFTSMRARGAQATDIVVLVVAADDGV-MPQTIEAI 96 >4RXU-A nrPDB Length = 367 Score = 32.3 bits (72), Expect = 0.45, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 8/75 (10%) Query: 185 LVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHV 244 LV H S P + + +GAA + A L G QP+ ++ I Sbjct: 146 LVDHASGTGNPLY------LYAGAASDNNAFLFFEGAWKVLQPKIAD--GTFVIKNSSEA 197 Query: 245 IILQNKVDLMREESA 259 + LQNK+DL R+E A Sbjct: 198 VALQNKLDLTRDEMA 212 >3CB4-D nrPDB Length = 599 Score = 32.0 bits (71), Expect = 0.65, Method: Compositional matrix adjust. Identities = 69/285 (24%), Positives = 114/285 (40%), Gaps = 54/285 (18%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNI--TIKLGYANAKIYKCQEPTCPEPD 159 N I H+ HGKST+ I + E+E + ++ L K Q T Sbjct: 6 NFSIIAHIDHGKSTLSDRIIQICGGLSDREMEAQVLDSMDLERERGITIKAQSVTLD--- 62 Query: 160 CYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIA 219 Y++ SD E Y+L +F+D PGH + A + ALL++ Sbjct: 63 -YKA--SDGET------------YQL----NFIDTPGHVDFSYEVSRSLAACEGALLVVD 103 Query: 220 GNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDL--MREESALEHQKSILKFIRGTIADG 277 + + A+E M L+ V +L NK+DL E E + I+ D Sbjct: 104 AGQGVEAQTLANCYTAME-MDLEVVPVL-NKIDLPAADPERVAEEIEDIVGI------DA 155 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGV 337 V SA+ + V E +V+ IP P D + ++I S+ ++ G V Sbjct: 156 TDAVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSW--------FDNYLGVV 207 Query: 338 AGGSILNGVFKLGDEIEI----------RPGIVT--KDDKGKIQC 370 + I NG + GD++++ R GI T + D+ +++C Sbjct: 208 SLIRIKNGTLRKGDKVKVMSTGQTYNADRLGIFTPKQVDRTELKC 252 >4XKM-A nrPDB Length = 458 Score = 31.6 bits (70), Expect = 1.00, Method: Compositional matrix adjust. Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 1/79 (1%) Query: 81 NPDFSKLNPLSAEIINR-QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIK 139 NPDF + + +I N ATI +G +V G ++ R K+ L + +TI Sbjct: 179 NPDFDVVARAAVQIKNAIDATIELGGENYVFWGGREGYMSLLNTDQKREKEHLAQMLTIA 238 Query: 140 LGYANAKIYKCQEPTCPEP 158 YA A+ +K P+P Sbjct: 239 RDYARARGFKGTFLIEPKP 257 >3WNB-A nrPDB Length = 370 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 44/193 (22%), Positives = 82/193 (42%), Gaps = 38/193 (19%) Query: 187 RHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQ---PQTSEHLAAIEIMKLKH 243 R++ FVD + + ++++ + D A+L I PQ T E + A++++ KH Sbjct: 60 RNMVFVDAHSYPKTLKSLITALNISDIAVLCIP-----PQGLDAHTGECIIALDLLGFKH 114 Query: 244 VIILQNKVDLMREESALEHQKSILKFI-RGTIADGAPIVPISA------------QLKYN 290 II + D A++ K+ LK I GT+ + ++ +LK Sbjct: 115 GIIALTRSDSTHMH-AIDELKAKLKVITSGTVLQDWECISLNTNKSAKNPFEGVDELKAR 173 Query: 291 IDAVNEFI------VKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIED-LKGGVAGGSIL 343 I+ V E I + ++P R+ + +F+V G + +K G++ Sbjct: 174 INEVAEKIEAENAELNSLP---------ARIFIDHAFNVTGKGCVVLGVVKQGISKDKDK 224 Query: 344 NGVFKLGDEIEIR 356 +F L +IEIR Sbjct: 225 TKIFPLDRDIEIR 237 >6MTD-v nrPDB Length = 839 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 42/161 (26%), Positives = 71/161 (44%), Gaps = 31/161 (19%) Query: 94 IINRQATI-NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQE 152 I++++A I N+ I HV HGKST+ ++ + + R ITIK A + Y+ E Sbjct: 11 IMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGI-----IARCITIK-STAISLFYELSE 64 Query: 153 PTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMD 212 + K K+ G L+ + +D PGH S + + V D Sbjct: 65 ------NDLNFIKQSKD-----------GAGFLI---NLIDSPGHVDFSSEVTAALRVTD 104 Query: 213 AALLLI-AGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVD 252 AL+++ + C Q +T A E +K +++ NK+D Sbjct: 105 GALVVVDCVSGVCVQTETVLRQAIAERIK---PVLMMNKMD 142 >6GB2-BC nrPDB Length = 657 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHL 233 ++F+D PGH + GA V D +L++A ++ + QT E + Sbjct: 160 ITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADDGVMK-QTVESI 203 >3IZY-P nrPDB Length = 537 Score = 30.0 bits (66), Expect = 2.5, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 6/66 (9%) Query: 189 VSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHV--II 246 ++F+D PGH + G V D +L++A ++ + QT E +I+ K HV ++ Sbjct: 54 ITFLDTPGHAAFSAMRARGTQVTDIVILVVAADDGVMK-QTVE---SIQHAKDAHVPIVL 109 Query: 247 LQNKVD 252 NK D Sbjct: 110 AINKCD 115 >3IEU-A nrPDB Length = 301 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 35/66 (53%), Gaps = 4/66 (6%) Query: 244 VIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIP 303 VI+ NKVD ++E++ L L+F+ + + IVPISA+ N+D + + K +P Sbjct: 119 VILAVNKVDNVQEKADLLPH---LQFLASQM-NFLDIVPISAETGLNVDTIAAIVRKHLP 174 Query: 304 VPPRDF 309 F Sbjct: 175 EATHHF 180 >4UJC-AB nrPDB Length = 627 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 35/154 (22%), Positives = 68/154 (44%), Gaps = 24/154 (15%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 I +GHV GK+ + + ++ +D IT ++G N + E T + Sbjct: 41 ICVLGHVDTGKTKI---LDKLRHTHVQDGEAGGITQQIGATNVPLEAINEQT----KMIK 93 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 +F D+E + PG + +D PGH+ + G+++ D A+L++ Sbjct: 94 NF--DRE---NVRIPG----------MLIIDTPGHESFSNLRNRGSSLCDIAILVVDIMH 138 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMRE 256 +PQT E + ++ K ++ L NK+D + + Sbjct: 139 GL-EPQTIESINLLKSKKCPFIVAL-NKIDRLYD 170 >2ZY3-A nrPDB Length = 546 Score = 28.5 bits (62), Expect = 7.4, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 34/67 (50%), Gaps = 16/67 (23%) Query: 303 PVPPRDFMISPRLIVIRSFDVNKPGAE--------IEDLKGGVAGGSI------LNGVFK 348 PVPPR IS + ++R + + + GA+ + ++GG A + LNG+ K Sbjct: 135 PVPPRMLNISEK--IVRQYIIREMGADAIPSESVNLFAVEGGTAAMAYIFESLKLNGLLK 192 Query: 349 LGDEIEI 355 GD++ I Sbjct: 193 AGDKVAI 199 >4C65-A nrPDB Length = 438 Score = 28.1 bits (61), Expect = 10.0, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 32/63 (50%), Gaps = 4/63 (6%) Query: 73 GGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISG----VQTVRF 128 GG+ + NP+F++ +P ++I +A + HGK+ ++ AI ++ V + Sbjct: 209 GGVMSRDDNPNFAQFSPEELKVIVEEAARQNRIVSAHVHGKAGIMAAIKAGCKSLEHVSY 268 Query: 129 KDE 131 DE Sbjct: 269 ADE 271 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3J81-k nrPDB 763 0.0 6O81-S nrPDB 579 e-166 6FEC-S nrPDB 550 e-157 2D74-A nrPDB 508 e-144 1S0U-A nrPDB 497 e-141 3PEN-A nrPDB 458 e-129 3WXM-A nrPDB 273 1e-73 3MMP-A nrPDB 272 2e-73 4V5G-AZ nrPDB 272 2e-73 4ZV4-A nrPDB 270 9e-73 1JNY-A nrPDB 264 5e-71 5W75-A nrPDB 263 1e-70 3WY9-A nrPDB 259 2e-69 4J0Q-A nrPDB 256 2e-68 1D2E-A nrPDB 254 7e-68 1MJ1-A nrPDB 248 4e-66 5W76-A nrPDB 248 6e-66 1EFM-A nrPDB 245 4e-65 6MIJ-A nrPDB 243 1e-64 5W7Q-A nrPDB 241 5e-64 5LZD-z nrPDB 231 5e-61 5IZL-A nrPDB 229 2e-60 4C0S-A nrPDB 224 6e-59 5LZS-jj nrPDB 224 7e-59 2B7C-A nrPDB 222 3e-58 4AC9-A nrPDB 215 4e-56 2HDN-B nrPDB 202 4e-52 1ZUN-B nrPDB 200 1e-51 4ZU9-A nrPDB 195 3e-50 4D61-i nrPDB 190 2e-48 5LZT-jj nrPDB 188 7e-48 1R5O-A nrPDB 181 5e-46 3J4J-A nrPDB 166 2e-41 4KJZ-A nrPDB 166 3e-41 4B44-A nrPDB 164 7e-41 3MCA-A nrPDB 149 3e-36 1G7S-A nrPDB 116 3e-26 Sequences not found previously or not previously below threshold: 5LZY-jj nrPDB 165 4e-41 4CRN-P nrPDB 139 3e-33 3IZQ-1 nrPDB 135 6e-32 3P27-A nrPDB 132 4e-31 2LKD-A nrPDB 117 1e-26 6GB2-BC nrPDB 112 4e-25 5FG3-A nrPDB 108 9e-24 2YWH-A nrPDB 106 2e-23 3IZY-P nrPDB 106 2e-23 1ZO1-I nrPDB 103 2e-22 5YT0-A nrPDB 102 3e-22 3CB4-D nrPDB 102 4e-22 3JCN-b nrPDB 100 3e-21 5IMR-C nrPDB 99 4e-21 5J8B-z nrPDB 99 5e-21 5A9Z-CA nrPDB 95 6e-20 4NCL-A nrPDB 93 2e-19 4N3G-A nrPDB 93 3e-19 4UJC-AB nrPDB 92 6e-19 4TN1-B nrPDB 89 5e-18 4NCF-A nrPDB 89 5e-18 4V8Y-CP nrPDB 88 8e-18 3WBI-A nrPDB 88 1e-17 4V8Z-CV nrPDB 85 5e-17 5KCS-1w nrPDB 84 1e-16 4V6V-A1 nrPDB 81 1e-15 3WNB-A nrPDB 80 2e-15 4V6W-Az nrPDB 76 3e-14 5I4Q-C nrPDB 74 2e-13 5H7K-A nrPDB 73 3e-13 5H7J-A nrPDB 73 3e-13 2P8Y-T nrPDB 72 5e-13 5VH6-A nrPDB 70 2e-12 5TY0-A nrPDB 69 4e-12 4FN5-A nrPDB 68 1e-11 6N0I-A nrPDB 67 2e-11 3ZZ0-A nrPDB 67 2e-11 6MTD-v nrPDB 67 2e-11 6BK7-A nrPDB 65 7e-11 6ID0-C nrPDB 64 2e-10 1WDT-A nrPDB 63 5e-10 3VQT-A nrPDB 61 9e-10 4V89-AW nrPDB 61 9e-10 3TR5-A nrPDB 61 1e-09 4WQY-BZ nrPDB 61 2e-09 6B8D-A nrPDB 60 2e-09 5G06-P nrPDB 60 2e-09 4ZKD-A nrPDB 60 2e-09 5TV2-A nrPDB 60 3e-09 4V7D-BZ nrPDB 59 5e-09 3JB9-B nrPDB 58 1e-08 6NOT-A nrPDB 57 2e-08 5KH0-A nrPDB 53 3e-07 3R9W-A nrPDB 50 2e-06 1U0L-A nrPDB 48 8e-06 2QTH-A nrPDB 45 6e-05 1MKY-A nrPDB 45 7e-05 3PR1-A nrPDB 44 1e-04 5LAD-A nrPDB 44 2e-04 3IEU-A nrPDB 43 2e-04 2CXX-A nrPDB 43 3e-04 3K53-A nrPDB 43 3e-04 2E87-A nrPDB 42 6e-04 3CLV-A nrPDB 41 0.001 3J8G-X nrPDB 40 0.002 1XZP-A nrPDB 40 0.002 2WJG-A nrPDB 39 0.004 1LNZ-A nrPDB 39 0.007 3GEH-A nrPDB 38 0.009 4HI0-E nrPDB 38 0.009 2F7S-A nrPDB 38 0.010 1EK0-A nrPDB 38 0.016 5HXB-X nrPDB 37 0.017 2QPT-A nrPDB 37 0.018 1YVD-A nrPDB 37 0.023 2WIC-A nrPDB 36 0.029 2IEZ-A nrPDB 36 0.034 2IEY-A nrPDB 36 0.036 4V62-AB nrPDB 36 0.051 2X77-A nrPDB 35 0.066 1UDX-A nrPDB 35 0.094 4MKI-B nrPDB 34 0.12 3H2Y-A nrPDB 34 0.13 2WJI-A nrPDB 34 0.14 4R98-A nrPDB 34 0.16 2QU8-A nrPDB 34 0.17 4DCU-A nrPDB 34 0.21 6EHH-A nrPDB 33 0.23 4PHF-A nrPDB 33 0.28 5LEF-A nrPDB 33 0.32 3ZYS-B nrPDB 33 0.33 5DN8-A nrPDB 33 0.34 5GTM-A nrPDB 33 0.38 6FNP-B nrPDB 33 0.47 2GIL-A nrPDB 33 0.51 4Z54-A nrPDB 32 0.68 1IZL-B nrPDB 32 0.81 1GA7-A nrPDB 32 0.88 3LRP-A nrPDB 31 0.94 2GJ9-A nrPDB 31 1.0 1YR7-A nrPDB 31 1.2 4HZU-A nrPDB 31 1.2 5B3F-A nrPDB 31 1.3 4P4S-B nrPDB 31 1.5 4P4S-A nrPDB 31 1.5 1T9H-A nrPDB 30 2.0 1EFP-B nrPDB 30 2.6 5NKM-B nrPDB 30 2.8 4G1U-C nrPDB 30 2.8 4YLG-A nrPDB 29 3.8 6N8N-W nrPDB 29 4.0 2YV5-A nrPDB 29 4.5 1VIA-A nrPDB 29 4.6 4V03-A nrPDB 29 5.2 5WDH-A nrPDB 29 5.3 5JB3-6 nrPDB 29 6.1 5DGX-A nrPDB 29 6.4 4A9A-A nrPDB 28 7.8 5JSZ-B nrPDB 28 7.9 5X7K-A nrPDB 28 9.8 >3J81-k nrPDB Length = 527 Score = 763 bits (1970), Expect = 0.0, Method: Composition-based stats. Identities = 527/527 (100%), Positives = 527/527 (100%) Query: 1 MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGET 60 MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGET Sbjct: 1 MSDLQDQEPSIIINGNLEPVGEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGET 60 Query: 61 EEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAI 120 EEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAI Sbjct: 61 EEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAI 120 Query: 121 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP 180 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP Sbjct: 121 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP 180 Query: 181 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK 240 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK Sbjct: 181 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK 240 Query: 241 LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK 300 LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK Sbjct: 241 LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVK 300 Query: 301 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV 360 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV Sbjct: 301 TIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIV 360 Query: 361 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK 420 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK Sbjct: 361 TKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAK 420 Query: 421 GHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKA 480 GHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKA Sbjct: 421 GHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKA 480 Query: 481 DMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA 527 DMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA Sbjct: 481 DMARLQLTSPACTEINEKIALSRRIEKHWRLIGWATIKKGTTLEPIA 527 >6O81-S nrPDB Length = 472 Score = 579 bits (1492), Expect = e-166, Method: Composition-based stats. Identities = 329/453 (72%), Positives = 384/453 (84%), Gaps = 2/453 (0%) Query: 75 LPEQPLNP-DFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELE 133 L Q L D +KL PLS E+I+RQATINIGTIGHVAHGKSTVV+AISGV TVRFK+ELE Sbjct: 15 LSRQDLTTLDVTKLTPLSHEVISRQATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELE 74 Query: 134 RNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVD 193 RNITIKLGYANAKIYK +P+CP P+CYRS S PG G +KLVRHVSFVD Sbjct: 75 RNITIKLGYANAKIYKLDDPSCPRPECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVD 134 Query: 194 CPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDL 253 CPGHDILM+TML+GAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKH++ILQNK+DL Sbjct: 135 CPGHDILMATMLNGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDL 194 Query: 254 MREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISP 313 ++E A E + IL F++GT+A+GAPI+PISAQLKYNI+ V E+IVK IPVPPRDF P Sbjct: 195 VKESQAKEQYEQILAFVQGTVAEGAPIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEP 254 Query: 314 RLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPI 373 RLIVIRSFDVNKPG E++DLKGGVAGGSIL GV K+G EIE+RPGIV+K +GK+ CKP Sbjct: 255 RLIVIRSFDVNKPGCEVDDLKGGVAGGSILKGVLKVGQEIEVRPGIVSKASEGKLMCKPK 314 Query: 374 FSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEIN 433 FS IVSLFAE NDL++A PGGLIGVGTK+DPTLCRADR+VGQV+GA G LP I+T++EI+ Sbjct: 315 FSKIVSLFAEHNDLQYAAPGGLIGVGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEIS 374 Query: 434 YFLLRRLLGVKTDGQKQ-AKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPAC 492 YFLLRRLLGV+T+G K+ AKV+KL NEVLMVNIGS +TG RV AVKAD+ ++ LT+P C Sbjct: 375 YFLLRRLLGVRTEGDKKAAKVQKLSKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVC 434 Query: 493 TEINEKIALSRRIEKHWRLIGWATIKKGTTLEP 525 TE+ EKIALSRR+EKHWRLIGW I++G T++P Sbjct: 435 TEVGEKIALSRRVEKHWRLIGWGQIRRGVTIKP 467 >6FEC-S nrPDB Length = 422 Score = 550 bits (1417), Expect = e-157, Method: Composition-based stats. Identities = 316/422 (74%), Positives = 365/422 (86%), Gaps = 1/422 (0%) Query: 98 QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE 157 QATINIGTIGHVAHGKSTVV+AISGV TVRFK+ELERNITIKLGYANAKIYK +P+CP Sbjct: 1 QATINIGTIGHVAHGKSTVVKAISGVHTVRFKNELERNITIKLGYANAKIYKLDDPSCPR 60 Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLL 217 P+CYRS S PG G +KLVRHVSFVDCPGHDILM+TML+GAAVMDAALLL Sbjct: 61 PECYRSCGSSTPDEFPTDIPGTKGNFKLVRHVSFVDCPGHDILMATMLNGAAVMDAALLL 120 Query: 218 IAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADG 277 IAGNESCPQPQTSEHLAAIEIMKLKH++ILQNK+DL++E A E + IL F++GT+A+G Sbjct: 121 IAGNESCPQPQTSEHLAAIEIMKLKHILILQNKIDLVKESQAKEQYEQILAFVQGTVAEG 180 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGV 337 API+PISAQLKYNI+ V E+IVK IPVPPRDF PRLIVIRSFDVNKPG E++DLKGGV Sbjct: 181 APIIPISAQLKYNIEVVCEYIVKKIPVPPRDFTSEPRLIVIRSFDVNKPGCEVDDLKGGV 240 Query: 338 AGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIG 397 AGGSIL GV K+G EIE+RPGIV+KD +GK+ CKPIFS IVSLFAE NDL++A PGGLIG Sbjct: 241 AGGSILKGVLKVGQEIEVRPGIVSKDSEGKLMCKPIFSKIVSLFAEHNDLQYAAPGGLIG 300 Query: 398 VGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQ-AKVRKL 456 VGTK+DPTLCRADR+VGQV+GA G LP I+T++EI+YFLLRRLLGV+T+G K+ AKV+KL Sbjct: 301 VGTKIDPTLCRADRMVGQVLGAVGALPEIFTELEISYFLLRRLLGVRTEGDKKAAKVQKL 360 Query: 457 EPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGWAT 516 NEVLMVNIGS +TG RV AVKAD+ ++ LT+P CTE+ EKIALSRR+EKHWRLIGW Sbjct: 361 SKNEVLMVNIGSLSTGGRVSAVKADLGKIVLTNPVCTEVGEKIALSRRVEKHWRLIGWGQ 420 Query: 517 IK 518 I+ Sbjct: 421 IR 422 >2D74-A nrPDB Length = 419 Score = 508 bits (1308), Expect = e-144, Method: Composition-based stats. Identities = 191/430 (44%), Positives = 279/430 (64%), Gaps = 19/430 (4%) Query: 90 LSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYK 149 + + RQA +NIG +GHV HGK+T+ +A++GV T +EL R ITIK+G+A+A+I + Sbjct: 1 MGEKRKTRQAEVNIGMVGHVDHGKTTLTKALTGVWTDTHSEELRRGITIKIGFADAEIRR 60 Query: 150 CQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAA 209 C + S P C + +R VSF+D PGH+ LM+TML+GA+ Sbjct: 61 CS--------------NCGRYSTSPICPYCGHETEFIRRVSFIDSPGHEALMTTMLAGAS 106 Query: 210 VMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKF 269 +MD A+L+IA NE CP+PQT EHL A++I+ K++II QNK++L+ +E ALE+ + I +F Sbjct: 107 LMDGAILVIAANEPCPRPQTREHLMALQIIGQKNIIIAQNKIELVDKEKALENYRQIKEF 166 Query: 270 IRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAE 329 I+GT+A+ API+PISA NID + + I + IP P RD P+++V+RSFDVNKPG Sbjct: 167 IKGTVAENAPIIPISALHGANIDVLVKAIEEFIPTPKRDSNKPPKMLVLRSFDVNKPGTP 226 Query: 330 IEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKF 389 E L GGV GSI+ G K+GDEIEIRPG V ++ G+I+ +PI + IVSL A ++ Sbjct: 227 PEKLVGGVLDGSIVQGKLKVGDEIEIRPG-VPYEEHGRIKYEPITTEIVSLQAGGQFVEE 285 Query: 390 AVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQK 449 A PGGL+G+GTK+DP L + D + G VVG G LP ++TD+ + LL R++G ++ Sbjct: 286 AYPGGLVGIGTKLDPYLTKGDLMAGNVVGKPGKLPPVWTDLRLEVHLLERVVGT----EQ 341 Query: 450 QAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHW 509 + V ++ EVL++N+G+ T V A+ D L+L P C E E++A+SR+I W Sbjct: 342 ELNVEPIKRKEVLLLNVGTARTMGLVTALGKDEIELKLQIPVCAEPGERVAISRQIGSRW 401 Query: 510 RLIGWATIKK 519 RLIG+ IK+ Sbjct: 402 RLIGYGIIKE 411 >1S0U-A nrPDB Length = 408 Score = 497 bits (1280), Expect = e-141, Method: Composition-based stats. Identities = 204/424 (48%), Positives = 280/424 (66%), Gaps = 19/424 (4%) Query: 95 INRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPT 154 + QA +NIG +GHV HGK+++ +A++GV T R +EL R I+I+LGYA C+ Sbjct: 3 LGSQAEVNIGMVGHVDHGKTSLTKALTGVWTDRHSEELRRGISIRLGYA-----DCEIRK 57 Query: 155 CPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAA 214 CP+ Y + K + P C + +R VSFVD PGH+ LM+TMLSGA++MD A Sbjct: 58 CPQCGTYTT---------KPRCPNCLAETEFLRRVSFVDSPGHETLMATMLSGASLMDGA 108 Query: 215 LLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI 274 +L+IA NE CPQPQT EHL A+EI+ + +II+QNK+DL+ E+ A E+ + I +F++GTI Sbjct: 109 ILVIAANEPCPQPQTKEHLMALEILGIDKIIIVQNKIDLVDEKQAEENYEQIKEFVKGTI 168 Query: 275 ADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLK 334 A+ API+PISA + NID + + I IP P RD +PR+ V RSFD+NKPG EI+DLK Sbjct: 169 AENAPIIPISAHHEANIDVLLKAIQDFIPTPKRDPDATPRMYVARSFDINKPGTEIKDLK 228 Query: 335 GGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGG 394 GGV GG+I+ GVFK+GDEIEIRPGI + K KP+ + IVSL A L+ A PGG Sbjct: 229 GGVLGGAIIQGVFKVGDEIEIRPGIKVTEGN-KTFWKPLTTKIVSLAAGNTILRKAHPGG 287 Query: 395 LIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVR 454 LIGVGT +DP L ++D L G VVG G LP I I I LL R++G K ++ K+ Sbjct: 288 LIGVGTTLDPYLTKSDALTGSVVGLPGTLPPIREKITIRANLLDRVVGTK----EELKIE 343 Query: 455 KLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIGW 514 L EVLM+NIG+ T + + + D+A ++L P C EI +++A+SRR+ WRLIG+ Sbjct: 344 PLRTGEVLMLNIGTATTAGVITSARGDIADIKLKLPICAEIGDRVAISRRVGSRWRLIGY 403 Query: 515 ATIK 518 TI+ Sbjct: 404 GTIE 407 >3PEN-A nrPDB Length = 403 Score = 458 bits (1177), Expect = e-129, Method: Composition-based stats. Identities = 176/423 (41%), Positives = 264/423 (62%), Gaps = 28/423 (6%) Query: 98 QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE 157 Q +NIG +GHV HGK+T+V+AI+G+ T + KLGYA I C+ +C + Sbjct: 6 QPEVNIGVVGHVDHGKTTLVQAITGIWTSK-----------KLGYAETNIGVCE--SCKK 52 Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLL 217 P+ Y + P C+ G K +R +SF+D PGH++LM+TMLSGAA+MD A+L+ Sbjct: 53 PEAYVT-------EPSCKSCGSDDEPKFLRRISFIDAPGHEVLMATMLSGAALMDGAILV 105 Query: 218 IAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADG 277 +A NE PQPQT EH A+ I+ +K++II+QNKVD++ +E AL + I +F +GT A+ Sbjct: 106 VAANEPFPQPQTREHFVALGIIGVKNLIIVQNKVDVVSKEEALSQYRQIKQFTKGTWAEN 165 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGV 337 PI+P+SA K NID++ E I + I P RD P ++VIRSFDVNKPG + +LKGGV Sbjct: 166 VPIIPVSALHKINIDSLIEGIEEYIKTPYRDLSQKPVMLVIRSFDVNKPGTQFNELKGGV 225 Query: 338 AGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIG 397 GGSI+ G+FK+ EI++ PG+ + +GK+ +PIF+ I S+ + K A PGGL+ Sbjct: 226 IGGSIIQGLFKVDQEIKVLPGLRV-EKQGKVSYEPIFTKISSIRFGDEEFKEAKPGGLVA 284 Query: 398 VGTKVDPTLCRADRLVGQVVG-AKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKL 456 +GT +DP+L +AD L+G ++ A +P ++ +I I Y LL R++G K + KV + Sbjct: 285 IGTYLDPSLTKADNLLGSIITLADAEVPVLW-NIRIKYNLLERVVGAK----EMLKVDPI 339 Query: 457 EPNEVLMVNIGSTATGARVVAVKADMARLQLTSPA-CTEINEKIALSRRIEKHWRLIGWA 515 E LM+++GS+ T V +VK D ++L P N + +SR+I WR+IGW Sbjct: 340 RAKETLMLSVGSSTTLGIVTSVKKDEIEVELRRPVAVWSNNIRTVISRQIAGRWRMIGWG 399 Query: 516 TIK 518 ++ Sbjct: 400 LVE 402 >3WXM-A nrPDB Length = 447 Score = 273 bits (698), Expect = 1e-73, Method: Composition-based stats. Identities = 73/379 (19%), Positives = 141/379 (37%), Gaps = 76/379 (20%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAI---------SGVQTVRFKDELERNITIKLGY 142 + + +N+ IGHV HGKST+V + ++ + + + + K + Sbjct: 1 GSHMAEKPHMNLVVIGHVDHGKSTLVGHLLYRLGYIEEKKLKELEEQAKSRGKESFKFAW 60 Query: 143 ANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMS 202 K+ + +E + F++ K + + +D PGH + Sbjct: 61 ILDKMKEERERGITIDLTFMKFETKKYV------------------FTIIDAPGHRDFVK 102 Query: 203 TMLSGAAVMDAALLLIAGNESCP------QPQTSEHLAAIEIMKLKHVIILQNKVDLMRE 256 M++GA+ DAA+L+++ + + QT EHL M ++ +I+ NK+D Sbjct: 103 NMITGASQADAAILVVSARKGEFEAGMSTEGQTREHLLLARTMGIEQIIVAVNKMDAPDV 162 Query: 257 ESALEHQKSILKFIR------GTIADGAPIVPISAQLK------------YNIDAVNEFI 298 + + ++ ++ G D P +P+SA YN + E + Sbjct: 163 NYDQKRYEFVVSVLKKFMKGLGYQVDKIPFIPVSAWKGDNLIERSPNMPWYNGPTLVEAL 222 Query: 299 VKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPG 358 + P P + R+ V + + G V G + GV ++GD++ P Sbjct: 223 DQLQP-PAKPVDKPLRIPVQNVYSIPGA--------GTVPVGRVETGVLRVGDKVVFMPP 273 Query: 359 IVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVG 418 V + S+ L+ A PG IG + + ++D G V G Sbjct: 274 GVV-------------GEVRSIEMHYQQLQQAEPGDNIGFAVR---GVSKSDIKRGDVAG 317 Query: 419 AKGHLPNIYTDIEINYFLL 437 P + + E F++ Sbjct: 318 HLDKPPTVAEEFEARIFVI 336 >3MMP-A nrPDB Length = 678 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 101/395 (25%), Positives = 159/395 (40%), Gaps = 69/395 (17%) Query: 69 FEEGGGLPEQPLNPDF-------SKLNPLSAEIINR-QATINIGTIGHVAHGKSTVVRAI 120 FE G G+ + + DF SK + +S E R + +N+GTIGHV HGK+T+ AI Sbjct: 259 FEVGEGI--EKVETDFAAEVAAMSKQSHMSKEKFERTKPHVNVGTIGHVDHGKTTLTAAI 316 Query: 121 SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCP 180 + V Y A Q PE + + Sbjct: 317 TTVLAKT--------------YGGAARAFDQIDNAPEEKARGITINTSHVEYDT------ 356 Query: 181 GRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMK 240 RH + VDCPGH + M++GAA MD A+L++A + P PQT EH+ + Sbjct: 357 ----PTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDG-PMPQTREHILLGRQVG 411 Query: 241 LKHVIILQNKVDLMREESALEHQKSILKFIRGTI---ADGAPIVPISAQLKYNIDAVNE- 296 + ++I+ NK D++ +E LE + ++ + D PIV SA DA E Sbjct: 412 VPYIIVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEA 471 Query: 297 -------FIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKL 349 F+ IP P R L + F ++ +G V G + G+ K+ Sbjct: 472 KILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISG--------RGTVVTGRVERGIIKV 523 Query: 350 GDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRA 409 G+E+EI V + K C + + L G +GV + + R Sbjct: 524 GEEVEI----VGIKETQKSTC-------TGVEMFRKLLDEGRAGENVGVLLR---GIKRE 569 Query: 410 DRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVK 444 + GQV+ G + +T E ++L + G + Sbjct: 570 EIERGQVLAKPGTIKP-HTKFESEVYILSKDEGGR 603 >4V5G-AZ nrPDB Length = 406 Score = 272 bits (696), Expect = 2e-73, Method: Composition-based stats. Identities = 85/377 (22%), Positives = 153/377 (40%), Gaps = 67/377 (17%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQ 151 E + + +N+GTIGHV HGK+T+ A++ V + + Sbjct: 4 GEFVRTKPHVNVGTIGHVDHGKTTLTAALTYVAAAENPNVEVK-------------DYGD 50 Query: 152 EPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVM 211 PE + + + + RH S VDCPGH + M++GAA M Sbjct: 51 IDKAPEERARGITINTAHVEYETAK----------RHYSHVDCPGHADYIKNMITGAAQM 100 Query: 212 DAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIR 271 D A+L+++ + P PQT EH+ + + ++++ NKVD++ + L+ + ++ + Sbjct: 101 DGAILVVSAADG-PMPQTREHILLARQVGVPYIVVFMNKVDMVDDPELLDLVEMEVRDLL 159 Query: 272 GTI---ADGAPIVPISAQLKYN---------------IDAVNEF---IVKTIPVPPRDFM 310 D P++ SA L +D + E I + IP P RD Sbjct: 160 NQYEFPGDEVPVIRGSALLALEQMHRNPKTRRGENEWVDKIWELLDAIDEYIPTPVRDVD 219 Query: 311 ISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQC 370 + V F + +G VA G I G K+GDE+EI + Sbjct: 220 KPFLMPVEDVFTITG--------RGTVATGRIERGKVKVGDEVEIV----------GLAP 261 Query: 371 KPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDI 430 + + + + + L+ + G +GV + + R + GQV+ G + +T Sbjct: 262 ETRRTVVTGVEMHRKTLQEGIAGDNVGVLLR---GVSREEVERGQVLAKPGSITP-HTKF 317 Query: 431 EINYFLLRRLLGVKTDG 447 E + ++L++ G + G Sbjct: 318 EASVYVLKKEEGGRHTG 334 >4ZV4-A nrPDB Length = 405 Score = 270 bits (691), Expect = 9e-73, Method: Composition-based stats. Identities = 95/452 (21%), Positives = 168/452 (37%), Gaps = 70/452 (15%) Query: 90 LSAEIINR-QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIY 148 ++ E R + +N+GTIGHV HGK+T+ A++ V + + + Sbjct: 1 MAKEKFERNKPHVNVGTIGHVDHGKTTLTAALTKVCSDT--------------WGGSARA 46 Query: 149 KCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGA 208 Q PE + + VRH + VDCPGH + M++GA Sbjct: 47 FDQIDNAPEEKARGITINTSHVEYDSA----------VRHYAHVDCPGHADYVKNMITGA 96 Query: 209 AVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILK 268 A MD A+L+ + + P PQT EH+ + + ++++ NK D++ + LE + ++ Sbjct: 97 AQMDGAILVCSAADG-PMPQTREHILLSRQVGVPYIVVFLNKADMVDDAELLELVEMEVR 155 Query: 269 FIRGTI---ADGAPIVPISAQLKYN-----------IDAVNEFIVKTIPVPPRDFMISPR 314 + T D PI+ SA + + + E + IP P R Sbjct: 156 DLLNTYDFPGDDTPIIIGSALMALEGKDDNGIGVSAVQKLVETLDSYIPEPVRAIDQPFL 215 Query: 315 LIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIF 374 + + F ++ +G V G + G+ K+ +E+EI V K C Sbjct: 216 MPIEDVFSISG--------RGTVVTGRVERGIIKVQEEVEI----VGIKATTKTTC---- 259 Query: 375 SNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINY 434 + + L G +G+ + R D GQV+ G + +T E Sbjct: 260 ---TGVEMFRKLLDEGRAGENVGILLR---GTKREDVERGQVLAKPGTIKP-HTKFECEV 312 Query: 435 FLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTS--PAC 492 ++L + G + + R V + + D ++ +T P Sbjct: 313 YVLSKEEGGRHTPFFK-GYRPQFYFRTTDVTGNCELPEGVEMVMPGDNIKMVVTLIAPIA 371 Query: 493 TEINEKIALSRRIEKHWRLIGWATIKKGTTLE 524 E + A+ R R +G + K LE Sbjct: 372 MEDGLRFAI--REGG--RTVGAGVVAKIIELE 399 >1JNY-A nrPDB Length = 435 Score = 264 bits (675), Expect = 5e-71, Method: Composition-based stats. Identities = 80/376 (21%), Positives = 150/376 (39%), Gaps = 76/376 (20%) Query: 95 INRQATINIGTIGHVAHGKSTVV------RAISGVQTVRFKDELERNI---TIKLGYANA 145 ++++ +N+ IGHV HGKST+V R +TV+ +E + + + K + Sbjct: 1 MSQKPHLNLIVIGHVDHGKSTLVGRLLMDRGFIDEKTVKEAEEAAKKLGKESEKFAFLLD 60 Query: 146 KIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTML 205 ++ + +E + F++ K + +D PGH + M+ Sbjct: 61 RLKEERERGVTINLTFMRFETKKYF------------------FTIIDAPGHRDFVKNMI 102 Query: 206 SGAAVMDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESA 259 +GA+ DAA+L+++ + + QT EH+ + M L +I+ NK+DL Sbjct: 103 TGASQADAAILVVSAKKGEYEAGMSVEGQTREHIILAKTMGLDQLIVAVNKMDLTEPPYD 162 Query: 260 LEHQKSIL----KFIR--GTIADGAPIVPISA------------QLKYNIDAVNEFIVKT 301 + K I+ KF+R G + VP+ A YN + E++ Sbjct: 163 EKRYKEIVDQVSKFMRSYGFNTNKVRFVPVVAPSGDNITHKSENMKWYNGPTLEEYL-DQ 221 Query: 302 IPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVT 361 + +PP+ R+ + + ++ G V G + +GV K+GD+I P Sbjct: 222 LELPPKPVDKPLRIPIQDVYSISGV--------GTVPVGRVESGVLKVGDKIVFMPA--- 270 Query: 362 KDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKG 421 GK+ + S+ + A PG IG + + + D G VVG Sbjct: 271 ----GKV------GEVRSIETHHTKMDKAEPGDNIGFNVR---GVEKKDIKRGDVVGHPN 317 Query: 422 HLPNIYTDIEINYFLL 437 + P + + ++ Sbjct: 318 NPPTVADEFTARIIVV 333 >5W75-A nrPDB Length = 392 Score = 263 bits (672), Expect = 1e-70, Method: Composition-based stats. Identities = 91/451 (20%), Positives = 171/451 (37%), Gaps = 83/451 (18%) Query: 97 RQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCP 156 + +N+GTIGHV HGKST+ AI+ +++ G A Y Q P Sbjct: 1 TKPHVNVGTIGHVDHGKSTLTAAITKYLSLK-------------GLAQYVPYD-QIDKAP 46 Query: 157 EPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALL 216 E + + + ++ RH + +DCPGH + M++GAA MD A+L Sbjct: 47 EEKARGITINITHVEYETEK----------RHYAHIDCPGHADYIKNMITGAAQMDGAIL 96 Query: 217 LIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI-- 274 ++A + P PQT EH+ + + ++I+ NK D++ + +E + ++ + Sbjct: 97 VVAATDG-PMPQTREHVLLARQVGVPYMIVFINKTDMVDDPELIELVEMEVRDLLSQYEY 155 Query: 275 -ADGAPIVPISAQLKYN------------IDAVNEFIVKTIPVPPRDFMISPRLIVIRSF 321 D P++ SA I + + + IP P RD + + F Sbjct: 156 PGDEVPVIKGSALKALEAPDDPNHEAYKPIQELLDAMDNYIPDPQRDVDKPFLMPIEDVF 215 Query: 322 DVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLF 381 + +G V G I G + GDE+EI + + + + S+ Sbjct: 216 SITG--------RGTVVTGRIERGRIRPGDEVEII----------GLSYEIRKTVVTSVE 257 Query: 382 AEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLL 441 + +L + G +G + + + + GQV+ A G + + + ++L++ Sbjct: 258 MFRKELDEGIAGDNVGCLLR---GIDKDEVERGQVLAAPGSIKP-HKRFKAEVYVLKKEE 313 Query: 442 GVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVV-------AVKAD--MARLQLTSPAC 492 G + I +T +V + D ++L P Sbjct: 314 GGRHT--------PFFKGYKPQFYIRTTDVTGEIVLPEGVEMVMPGDHVEMEIELIYPVA 365 Query: 493 TEINEKIALSRRIEKHWRLIGWATIKKGTTL 523 E ++ A+ R R +G + + L Sbjct: 366 IEKGQRFAI--REGG--RTVGAGVVTEVIEL 392 >3WY9-A nrPDB Length = 434 Score = 259 bits (662), Expect = 2e-69, Method: Composition-based stats. Identities = 79/354 (22%), Positives = 139/354 (39%), Gaps = 59/354 (16%) Query: 94 IINRQATINIGTIGHVAHGKSTV-------VRAISGVQTVRFKDELERNITIKLGYANAK 146 + + +NI IGHV HGKST I +F++ E+ + K + + Sbjct: 1 MPKEKPHVNIVFIGHVDHGKSTTIGRLLYDTGNIPETIIKKFEEMGEKGKSFKFAWVMDR 60 Query: 147 IYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLS 206 + + +E + F++ R+++ +D PGH + M++ Sbjct: 61 LKEERERGITIDVAHTKFET------------------PHRYITIIDAPGHRDFVKNMIT 102 Query: 207 GAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQK- 264 GA+ DAA+L++A + PQT EH + +KH+I+ NK+D++ ++ E K Sbjct: 103 GASQADAAVLVVAATDGV-MPQTKEHAFLARTLGIKHIIVTINKMDMVNYDQKVFEKVKA 161 Query: 265 SILKFIRGTIADGAPIVPISAQLK------------YNIDAVNEFIVKTIPVPPRDFMIS 312 + K ++ P++P SA YN + E + IP P + Sbjct: 162 QVEKLLKTLGYKDFPVIPTSAWNGDNVVKKSDKMPWYNGPTLIEAL-DQIPEPEKPIDKP 220 Query: 313 PRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKP 372 R+ + + + G V G + G K+GD + P I KP Sbjct: 221 LRIPIQDVYSIKGV--------GTVPVGRVETGKLKVGDVVIFEPA-------STIFHKP 265 Query: 373 IFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNI 426 I + S+ L+ A+PG IG + + + D G V G P + Sbjct: 266 IQGEVKSIEMHHEPLQEALPGDNIGFNVR---GVSKNDIKRGDVAGHTDKPPTV 316 >4J0Q-A nrPDB Length = 433 Score = 256 bits (653), Expect = 2e-68, Method: Composition-based stats. Identities = 79/379 (20%), Positives = 144/379 (37%), Gaps = 68/379 (17%) Query: 86 KLNPLSAEIINRQ------ATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIK 139 + +E + ++ +N+GTIGHV HGK+T+ A++ V + Sbjct: 28 QQMGRGSEFMAKEKFDRSLPHVNVGTIGHVDHGKTTLTAALTRVCSEV------------ 75 Query: 140 LGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDI 199 + +A + + + PE + + +RH + VDCPGH Sbjct: 76 --FGSAIVEFDKIDSAPEEKARGITINTAHVEYNS----------TIRHYAHVDCPGHAD 123 Query: 200 LMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESA 259 + M++GAA MD A+L+ + + P PQT EH+ + + ++++ NK DL+ + Sbjct: 124 YVKNMITGAAQMDGAILVCSAADG-PMPQTREHILLSRQVGVPYIVVFLNKADLVDDAEL 182 Query: 260 LEHQKSILKFIRGTI---ADGAPIVPISAQLKYNIDAVNEF-----------IVKTIPVP 305 LE + ++ + T D PI+ SA++ NE + IP P Sbjct: 183 LELVEMEVRDLLSTYDFPGDDTPIIIGSARMALEGKDDNEMGTTAVKKLVETLDSYIPEP 242 Query: 306 PRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDK 365 R + + F ++ +G V G I G+ ++ D +EI Sbjct: 243 VRAIDQPFLMPIEDVFSISG--------RGTVVTGRIERGIVRVQDPLEIV--------- 285 Query: 366 GKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPN 425 + + + L G GV + R D GQV+ G + Sbjct: 286 --GLRDTTTTTCTGVEMFRKLLDEGRAGENCGVLLR---GTKRDDVERGQVLVKPGSVKP 340 Query: 426 IYTDIEINYFLLRRLLGVK 444 +T ++L + G + Sbjct: 341 -HTKFTAEVYVLSKEEGGR 358 >1D2E-A nrPDB Length = 397 Score = 254 bits (648), Expect = 7e-68, Method: Composition-based stats. Identities = 83/360 (23%), Positives = 143/360 (39%), Gaps = 61/360 (16%) Query: 98 QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPE 157 + +N+GTIGHV HGK+T+ AI+ + + G A K Y+ + PE Sbjct: 1 KPHVNVGTIGHVDHGKTTLTAAITKILA-------------EGGGAKFKKYE-EIDNAPE 46 Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLL 217 + + RH + DCPGH + M++G A +D +L+ Sbjct: 47 ERARGITINAAHVEYSTA----------ARHYAHTDCPGHADYVKNMITGTAPLDGCILV 96 Query: 218 IAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIR---GTI 274 +A N+ P PQT EHL + ++HV++ NK D +++ +E + ++ + G Sbjct: 97 VAANDG-PMPQTREHLLLARQIGVEHVVVYVNKADAVQDSEMVELVELEIRELLTEFGYK 155 Query: 275 ADGAPIVPISAQLK----------YNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVN 324 + PI+ SA ++ + + + IPVP RD L V + + Sbjct: 156 GEETPIIVGSALCALEQRDPELGLKSVQKLLDAVDTYIPVPTRDLEKPFLLPVESVYSIP 215 Query: 325 KPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQ 384 +G V G++ G+ K GDE E K I + + + Sbjct: 216 G--------RGTVVTGTLERGILKKGDECEFL-----------GHSKNIRTVVTGIEMFH 256 Query: 385 NDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVK 444 L A G +G + L R D G V+ G + + +E ++L + G + Sbjct: 257 KSLDRAEAGDNLGALVR---GLKREDLRRGLVMAKPGSIQP-HQKVEAQVYILTKEEGGR 312 >1MJ1-A nrPDB Length = 405 Score = 248 bits (633), Expect = 4e-66, Method: Composition-based stats. Identities = 81/377 (21%), Positives = 151/377 (40%), Gaps = 67/377 (17%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQ 151 E I + +N+GTIGHV HGK+T+ A++ V RN+ +K Sbjct: 3 GEFIRTKRHVNVGTIGHVDHGKTTLTAALTYVAAAE-----NRNVEVK--------DYGD 49 Query: 152 EPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVM 211 E + + + + RH S VDC GH + M++GAA M Sbjct: 50 IDKAREERARGITINTAHVEYETAK----------RHYSHVDCRGHADYIKNMITGAAQM 99 Query: 212 DAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIR 271 D A+L+++ + QT EH+ + ++++++ NKVD++ + L+ + ++ + Sbjct: 100 DGAILVVSAADG-RMRQTREHILLARQVGVRYIVVFMNKVDMVDDRELLDLVEMEVRDLL 158 Query: 272 GTI---ADGAPIVPISAQLKYN---------------IDAVNEF---IVKTIPVPPRDFM 310 D ++ SA L +D + E I + I RD Sbjct: 159 NQYEFRGDEVRVIRGSALLALEEMHKNRKTKRGENEWVDKIWELLDAIDEYIRTRVRDVD 218 Query: 311 ISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQC 370 + V F + +G VA G I G K+GDE+EI + Sbjct: 219 KRFLMRVEDVFTITG--------RGTVATGRIERGKVKVGDEVEIV----------GLAR 260 Query: 371 KPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDI 430 + + + + + L+ + G +G+ + + R + GQV+ +G + +T Sbjct: 261 ETRKTVVTGVEMHRKTLQEGIAGDNVGLLLR---GVSREEVERGQVLAKRGSI-TRHTKF 316 Query: 431 EINYFLLRRLLGVKTDG 447 E + ++L++ G + G Sbjct: 317 EASVYILKKEEGGRHTG 333 >5W76-A nrPDB Length = 385 Score = 248 bits (632), Expect = 6e-66, Method: Composition-based stats. Identities = 99/435 (22%), Positives = 171/435 (39%), Gaps = 65/435 (14%) Query: 97 RQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCP 156 + +NIGTIGHV HGK+T+ AI+ V + G A K Y Q P Sbjct: 1 TKPHVNIGTIGHVDHGKTTLTAAITKVLAEK-------------GQAEFKAYD-QIDKAP 46 Query: 157 EPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALL 216 E S + + + RH + VDCPGH + M++GAA MD A+L Sbjct: 47 EEKERGITISTAHVEYETEN----------RHYAHVDCPGHADYVKNMITGAAQMDGAIL 96 Query: 217 LIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI-- 274 +++ + P PQT EH+ + + ++++ NKVD++ +E LE + ++ + + Sbjct: 97 VVSAADG-PMPQTREHILLARQVGVPYIVVFLNKVDMVDDEELLELVEMEVRELLSSYDF 155 Query: 275 -ADGAPIVPISAQLKYNIDAVNE--------FIVKTIPVPPRDFMISPRLIVIRSFDVNK 325 D PI+ SA D E + IP P R + + F ++ Sbjct: 156 PGDDIPIIKGSALKALEGDEEGEEAIMKLMDAVDSYIPEPERAIDKPFLMPIEDVFSIS- 214 Query: 326 PGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQN 385 +G V G + G+ K+G+E+EI V D K C + + Sbjct: 215 --------RGTVVTGRVERGIVKVGEEVEI----VGIRDTQKTTC-------TGVEMFRK 255 Query: 386 DLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKT 445 L G +GV + R D GQV+ G + +T + ++L + G + Sbjct: 256 LLDEGQAGDNVGVLLR---GTKREDVERGQVLAKPGSIKP-HTKFKAEVYILTKEEGGRH 311 Query: 446 DGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADM-ARLQLTSPACTEINEKIALSRR 504 + + + + G +V ++ ++L +P E + A+ R Sbjct: 312 TPFFNGYRPQFYFRTTDVTGVITLPEGVEMVMPGDNVTITVELIAPIAMEEGLRFAI--R 369 Query: 505 IEKHWRLIGWATIKK 519 R +G + + Sbjct: 370 EGG--RTVGAGVVSE 382 >1EFM-A nrPDB Length = 379 Score = 245 bits (625), Expect = 4e-65, Method: Composition-based stats. Identities = 104/447 (23%), Positives = 168/447 (37%), Gaps = 89/447 (19%) Query: 91 SAEIINR-QATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYK 149 S E R + +N+GTIGHV HGK+T+ AI+ V + R ITI + Sbjct: 1 SKEKFERTKPHVNVGTIGHVDHGKTTLTAAITTVLAKTYGG-AARGITINTSHVEYD--- 56 Query: 150 CQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAA 209 RH + VDCPGH + M++GAA Sbjct: 57 ----------------------------------TPTRHYAHVDCPGHADYVKNMITGAA 82 Query: 210 VMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKF 269 MD A+L++A + P PQT EH+ + + ++I+ NK D++ +E LE + ++ Sbjct: 83 QMDGAILVVAATDG-PMPQTREHILLGRQVGVPYIIVFLNKCDMVDDEELLELVEMEVRE 141 Query: 270 IRGTI---ADGAPIVPISAQLKYNIDAVNE--------FIVKTIPVPPRDFMISPRLIVI 318 + D PIV SA DA E F+ IP P R L + Sbjct: 142 LLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIE 201 Query: 319 RSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIV 378 F ++ +G V G + G+ K+G+E+EI V + K C Sbjct: 202 DVFSISG--------RGTVVTGRVERGIIKVGEEVEI----VGIKETQKSTC-------T 242 Query: 379 SLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLR 438 + + L G +GV + + R + GQV+ G + +T E ++L Sbjct: 243 GVEMFRKLLDEGRAGENVGVLLR---GIKREEIERGQVLAKPGTIKP-HTKFESEVYIL- 297 Query: 439 RLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATG----ARVVAVKADMARLQLTS--PAC 492 K +G + K + T T + + D ++ +T P Sbjct: 298 ----SKDEGGRHTPFFKGYRPQFYFRTTDVTGTIELPEGVEMVMPGDNIKMVVTLIHPIA 353 Query: 493 TEINEKIALSRRIEKHWRLIGWATIKK 519 + + A+ R R +G + K Sbjct: 354 MDDGLRFAI--REGG--RTVGAGVVAK 376 >6MIJ-A nrPDB Length = 396 Score = 243 bits (620), Expect = 1e-64, Method: Composition-based stats. Identities = 91/443 (20%), Positives = 164/443 (37%), Gaps = 68/443 (15%) Query: 92 AEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQ 151 A+ + +N+GTIGHV HGK+T+ AI+ + + E + Q Sbjct: 4 AKFERNKPHVNVGTIGHVDHGKTTLTAAIATICAKTYGGEAK--------------DYSQ 49 Query: 152 EPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVM 211 + PE + + RH + VDCPGH + M++GAA M Sbjct: 50 IDSAPEEKARGITINTSHVEYDS----------PTRHYAHVDCPGHADYVKNMITGAAQM 99 Query: 212 DAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIR 271 D A+L+ A + P PQT EH+ + + ++I+ NK DL+ +E LE + ++ + Sbjct: 100 DGAILVCAATDG-PMPQTREHILLSRQVGVPYIIVFLNKCDLVDDEELLELVEMEVRELL 158 Query: 272 GTI---ADGAPIVPISAQLKYNID----------AVNEFIVKTIPVPPRDFMISPRLIVI 318 T D P++ SA N + A+ + IP P R + + + Sbjct: 159 STYDFPGDDTPVIRGSALAALNGEAGPYGEESVLALVAALDSYIPEPERAIDKAFLMPIE 218 Query: 319 RSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIV 378 F ++ +G V G + G+ K+G+E+EI + + + Sbjct: 219 DVFSISG--------RGTVVTGRVEAGIIKVGEEVEIV-----------GIKDTVKTTVT 259 Query: 379 SLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLR 438 + + L G G+ + R + GQV+ G + +T + ++L Sbjct: 260 GVEMFRKLLDEGRAGENCGILLR---GTKREEVQRGQVLAKPGTIKP-HTKFDAEVYVLS 315 Query: 439 RLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMAR--LQLTSPACTEIN 496 + G + R V + + D ++L P + Sbjct: 316 KEEGGRHTPFLN-GYRPQFYFRTTDVTGAIQLKEGVEMVMPGDNVEMSVELIHPIAMDPG 374 Query: 497 EKIALSRRIEKHWRLIGWATIKK 519 + A+ R R +G + K Sbjct: 375 LRFAI--REGG--RTVGAGVVAK 393 >5W7Q-A nrPDB Length = 373 Score = 241 bits (615), Expect = 5e-64, Method: Composition-based stats. Identities = 87/360 (24%), Positives = 143/360 (39%), Gaps = 72/360 (20%) Query: 96 NRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTC 155 + +NIGTIGHV HGK+T+ AI+ V + G A AK Y Q Sbjct: 1 RTKPHVNIGTIGHVDHGKTTLTAAITTVLAKK-------------GGAEAKAYD-QIDNA 46 Query: 156 PEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAAL 215 PE + + + + RH + VDCPGH + M++GAA MD A+ Sbjct: 47 PEEKARGITINTAHVEYETEN----------RHYAHVDCPGHADYVKNMITGAAQMDGAI 96 Query: 216 LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI- 274 L+++ + P PQT EH+ + + ++++ NK D++ +E LE + ++ + Sbjct: 97 LVVSAADG-PMPQTREHILLARQVGVPYIVVFLNKCDMVDDEELLELVEMEVRELLSEYD 155 Query: 275 --ADGAPIVPISAQLKYNIDAVNE--------FIVKTIPVPPRDFMISPRLIVIRSFDVN 324 D PI+ SA DA E + IP P RD + + F ++ Sbjct: 156 FPGDDIPIIRGSALKALEGDAEWEDKILELMDAVDSYIPTPERDIDKPFLMPIEDVFSIS 215 Query: 325 KPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQ 384 +G V G + G+ K+G+E+EI GI + + + Sbjct: 216 G--------RGTVVTGRVERGIVKVGEEVEIV-GIKDTQK----------TTVTGVEMVG 256 Query: 385 NDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVK 444 L+ R D GQV+ G + +T E ++L + G + Sbjct: 257 ALLR----------------GTKREDVERGQVLAKPGSITP-HTKFEAEVYVLSKEEGGR 299 >5LZD-z nrPDB Length = 614 Score = 231 bits (589), Expect = 5e-61, Method: Composition-based stats. Identities = 97/414 (23%), Positives = 164/414 (39%), Gaps = 85/414 (20%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 I T GHV HGK+T+++AI+GV R +E +R +TI LGYA + P Sbjct: 3 IATAGHVDHGKTTLLQAITGVNADRLPEEKKRGMTIDLGYAYWPQPDGRVPG-------- 54 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 F+D PGH+ +S ML+G +D ALL++A ++ Sbjct: 55 ----------------------------FIDVPGHEKFLSNMLAGVGGIDHALLVVACDD 86 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 QT EHLA +++ + + K D + E E ++ + + +R A + Sbjct: 87 GV-MAQTREHLAILQLTGNPMLTVALTKADRVDEARVDEVERQVKEVLREYGFAEAKLFI 145 Query: 283 ISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSI 342 +A +DA+ E ++ +P S RL + R+F V G V G+ Sbjct: 146 TAATEGRGMDALREHLL-QLPEREHASQHSFRLAIDRAFTVKGAGL--------VVTGTA 196 Query: 343 LNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKV 402 L+G K+GD + + KP+ + +L A+ + A G I + Sbjct: 197 LSGEVKVGDSLWL-----------TGVNKPM--RVRALHAQNQPTETANAGQRIALNIAG 243 Query: 403 DPT---LCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPN 459 D + R D L+ V P +T + + L T L Sbjct: 244 DAEKEQINRGDWLLADV------PPEPFTRVIVE-------LQTHT---------PLTQW 281 Query: 460 EVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIEKHWRLIG 513 + L ++ ++ RV ++ ++A L +P N+++ L R I L G Sbjct: 282 QPLHIHHAASHVTGRVSLLEDNLAELVFDTPLWLADNDRLVL-RDISARNTLAG 334 >5IZL-A nrPDB Length = 616 Score = 229 bits (584), Expect = 2e-60, Method: Composition-based stats. Identities = 95/408 (23%), Positives = 169/408 (41%), Gaps = 72/408 (17%) Query: 87 LNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDE----LERNITIKLGY 142 L P + + R+ +N+G +GH+ GK+ + RA+S + D+ ER IT+ LG+ Sbjct: 14 LVPRGSHMAGRRVNVNVGVLGHIDSGKTALARALSTTASTAAFDKQPQSRERGITLDLGF 73 Query: 143 ANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMS 202 + + P P RS + P + + V+ VDCPGH L+ Sbjct: 74 SCFSV--------PLPARLRSSLP----EFQAAPEAEPEPGEPLLQVTLVDCPGHASLIR 121 Query: 203 TMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM----REES 258 T++ GA ++D +L+I + Q Q++E L +I K ++++ NK+DL+ R+ + Sbjct: 122 TIIGGAQIIDLMMLVIDVTKGM-QTQSAECLVIGQIACQK-LVVVLNKIDLLPEGKRQAA 179 Query: 259 ALEHQKSILKFIRGTIADGAPIVPISAQLK----------YNIDAVNEFIVKTIPVPPRD 308 + K + K + T GAPI+P++A+ I + E + I +P RD Sbjct: 180 IDKMTKKMQKTLENTKFRGAPIIPVAAKPGGPEAPETEAPQGIPELIELLTSQISIPTRD 239 Query: 309 FMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKI 368 + V F + +G V G+IL+G LGD +EI P + Sbjct: 240 PSGPFLMSVDHCFSIKG--------QGTVMTGTILSGSISLGDSVEI-PAL--------- 281 Query: 369 QCKPIFSNIVSLFAEQNDLKFAVPGGLIGV-GTKVDPTLCRADRLVGQVVGAKGHLPNIY 427 + + S+ + A+ G +G+ T+ DP L G +V A L ++ Sbjct: 282 ---KVVKKVKSMQMFHMPITSAMQGDRLGICVTQFDPKL----LERG-LVCAPESLHTVH 333 Query: 428 TDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARV 475 + I+ + G L+ + +G R+ Sbjct: 334 AAL-ISVEKIPYFRG------------PLQTKAKFHITVGHETVMGRL 368 >4C0S-A nrPDB Length = 463 Score = 224 bits (571), Expect = 6e-59, Method: Composition-based stats. Identities = 72/384 (18%), Positives = 125/384 (32%), Gaps = 77/384 (20%) Query: 94 IINRQATINIGTIGHVAHGKSTVVRAIS---GVQTVRFKDELERNITIKLGYANAKIYKC 150 + + INI IGHV GKST + G R ++ E+ ++G + K Sbjct: 1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA-EMGKGSFKYAWV 59 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 + E + + + +++ +D PGH + M++G + Sbjct: 60 LDKLKAERERGITIDISLWKFETTKY-----------YITIIDAPGHRDFIKNMITGTSQ 108 Query: 211 MDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQK 264 D A+L++A QT EH + +K +I+ NK+D + + Sbjct: 109 ADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPAYSEKRYD 168 Query: 265 SILKFIR------GTIADGAPIVPISAQLKYNI------------------------DAV 294 I+K + G P VPIS N+ ++ Sbjct: 169 EIVKEVSAYIKKIGYNPATVPFVPISGWHGDNMLEPSPNMPWFKGWKVERKEGNASGVSL 228 Query: 295 NEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIE 354 E + +P P R RL + + + G V G + G+ + G + Sbjct: 229 LEALDTILP-PTRPTDKPLRLPLQDVYKIGGI--------GTVPVGRVETGILRPGMVVT 279 Query: 355 IRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVG 414 P I + + S+ L A+PG +G K + D G Sbjct: 280 FAP-------------VNITTEVKSVEMHHEALSEALPGDNVGFNVK---NVSVKDIRRG 323 Query: 415 QVVG-AKGHLPNIYTDIEINYFLL 437 V G +K P +L Sbjct: 324 NVCGDSKSDPPQEAAQFTSQVIIL 347 >5LZS-jj nrPDB Length = 462 Score = 224 bits (571), Expect = 7e-59, Method: Composition-based stats. Identities = 78/384 (20%), Positives = 127/384 (33%), Gaps = 77/384 (20%) Query: 94 IINRQATINIGTIGHVAHGKSTVVRAIS---GVQTVRFKDELERNITIKLGYANAKIYKC 150 + + INI IGHV GKST + G R ++ E+ ++G + K Sbjct: 1 MGKEKTHINIVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA-EMGKGSFKYAWV 59 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 + E + R D + +V+ +D PGH + M++G + Sbjct: 60 LDKLKAERE--RGITIDISLWKFETSKY---------YVTIIDAPGHRDFIKNMITGTSQ 108 Query: 211 MDAALLLIAGNES------CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQK 264 D A+L++A QT EH + +K +I+ NK+D + + + Sbjct: 109 ADCAVLIVAAGVGEFEAGISKNGQTREHALLAYTLGVKQLIVGVNKMDSTEPPYSQKRYE 168 Query: 265 SILKFIR------GTIADGAPIVPISAQLKYNI------------------------DAV 294 I+K + G D VPIS N+ + Sbjct: 169 EIVKEVSTYIKKIGYNPDTVAFVPISGWNGDNMLEPSANMPWFKGWKVTRKDGNASGTTL 228 Query: 295 NEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIE 354 E + +P P R RL + + + G V G + GV K G + Sbjct: 229 LEALDCILP-PTRPTDKPLRLPLQDVYKIGGI--------GTVPVGRVETGVLKPGMVVT 279 Query: 355 IRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVG 414 P VT + + S+ L A+PG +G K + D G Sbjct: 280 FAPVNVT-------------TEVKSVEMHHEALSEALPGDNVGFNVK---NVSVKDVRRG 323 Query: 415 QVVG-AKGHLPNIYTDIEINYFLL 437 V G +K P +L Sbjct: 324 NVAGDSKNDPPMEAAGFTAQVIIL 347 >2B7C-A nrPDB Length = 458 Score = 222 bits (565), Expect = 3e-58, Method: Composition-based stats. Identities = 83/382 (21%), Positives = 128/382 (33%), Gaps = 75/382 (19%) Query: 94 IINRQATINIGTIGHVAHGKSTVVRAIS---GVQTVRFKDELERNITIKLGYANAKIYKC 150 + ++ IN+ IGHV GKST + G R ++ E+ +LG + K Sbjct: 1 MGKEKSHINVVVIGHVDSGKSTTTGHLIYKCGGIDKRTIEKFEKEAA-ELGKGSFKYAWV 59 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 + E + R D + V+ +D PGH + M++G + Sbjct: 60 LDKLKAERE--RGITIDIALWKFETPKY---------QVTVIDAPGHRDFIKNMITGTSQ 108 Query: 211 MDAALLLIAGNESCPQ------PQTSEHLAAIEIMKLKHVIILQNKVDLM--REESALEH 262 D A+L+IAG + QT EH + ++ +I+ NK+D + E E Sbjct: 109 ADCAILIIAGGVGEFEAGISKDGQTREHALLAFTLGVRQLIVAVNKMDSVKWDESRFQEI 168 Query: 263 QKSILKFIR--GTIADGAPIVPISAQLKYNI------------------------DAVNE 296 K FI+ G P VPIS N+ + E Sbjct: 169 VKETSNFIKKVGYNPKTVPFVPISGWNGDNMIEATTNAPWYKGWEKETKAGVVKGKTLLE 228 Query: 297 FIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIR 356 I I P R RL + + + G V G + GV K G + Sbjct: 229 AI-DAIEQPSRPTDKPLRLPLQDVYKIGGI--------GTVPVGRVETGVIKPGMVVTFA 279 Query: 357 PGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQV 416 P VT + + S+ L+ VPG +G K + + G V Sbjct: 280 PAGVT-------------TEVKSVEMHHEQLEQGVPGDNVGFNVK---NVSVKEIRRGNV 323 Query: 417 VG-AKGHLPNIYTDIEINYFLL 437 G AK P +L Sbjct: 324 CGDAKNDPPKGCASFNATVIVL 345 >4AC9-A nrPDB Length = 482 Score = 215 bits (547), Expect = 4e-56, Method: Composition-based stats. Identities = 83/453 (18%), Positives = 182/453 (40%), Gaps = 101/453 (22%) Query: 100 TINIGTIGHVAHGKSTVVRAISGVQTVRFKDEL----ERNITIKLGYANAKIYKCQEPTC 155 IN+G GH+ HGK+T+ + ++ + + D+L +R ITI +G++ K+ Sbjct: 19 NINLGIFGHIDHGKTTLSKVLTEIASTSAHDKLPESQKRGITIDIGFSAFKLENY----- 73 Query: 156 PEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAAL 215 ++ VD PGH L+ ++S A ++D AL Sbjct: 74 --------------------------------RITLVDAPGHADLIRAVVSAADIIDLAL 101 Query: 216 LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIA 275 +++ E P+ QT EH+ ++ + ++++ + EE ++ + I+K I + Sbjct: 102 IVVDAKEG-PKTQTGEHMLILDHFNIPIIVVITKSDNAGTEE--IKRTEMIMKSILQSTH 158 Query: 276 D--GAPIVPISAQLKYNIDAVNEFIVKTIPVPP--RDFMISPRLIVIRSFDVNKPGAEIE 331 + + I+PISA+ + +D + I+ T+ R+ ++ + +F + Sbjct: 159 NLKNSSIIPISAKTGFGVDELKNLIITTLNNAEIIRNTESYFKMPLDHAFPIKGA----- 213 Query: 332 DLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAV 391 G V G+I G+ K+GDE+++ P + + + S+ + + A Sbjct: 214 ---GTVVTGTINKGIVKVGDELKVLP-------------INMSTKVRSIQYFKESVMEAK 257 Query: 392 PGGLIGVGTKVDPTLCRADRLVGQVVGAKG----HLPNIYTDIEI----NYFLLRRL--- 440 G +G+ + + G ++ +K + I I+I Y L ++ Sbjct: 258 AGDRVGMAIQ---GVDAKQIYRGCILTSKDTKLQTVDKIVAKIKISDIFKYNLTPKMKVH 314 Query: 441 --LGVKTDGQKQAKVRKL---EPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEI 495 +G+ +K+ + E +++N V++ +L E+ Sbjct: 315 LNVGMLIVPAVAVPFKKVTFGKTEENIILN--------EVISGNECYCAFELEEKVLAEV 366 Query: 496 NEKIALSR--RIEKHWRLIGWATIKKGTTLEPI 526 +++ ++R R+ G I++ +PI Sbjct: 367 GDRVLITRLDLPPTTLRICGHGLIEE---FKPI 396 >2HDN-B nrPDB Length = 335 Score = 202 bits (512), Expect = 4e-52, Method: Composition-based stats. Identities = 83/352 (23%), Positives = 139/352 (39%), Gaps = 50/352 (14%) Query: 185 LVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHV 244 RH + VDCPGH + M++GAA MD A+L++A + P PQT EH+ + + ++ Sbjct: 14 PTRHYAHVDCPGHADYVKNMITGAAQMDGAILVVAATDG-PMPQTREHILLGRQVGVPYI 72 Query: 245 IILQNKVDLMREESALEHQKSILKFIRGTI---ADGAPIVPISAQLKYNIDAVNE----- 296 I+ NK D++ +E LE + ++ + D PIV SA DA E Sbjct: 73 IVFLNKCDMVDDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILE 132 Query: 297 ---FIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEI 353 F+ IP P R L + F ++ +G V G + G+ K+G+E+ Sbjct: 133 LAGFLDSYIPEPERAIDKPFLLPIEDVFSISG--------RGTVVTGRVERGIIKVGEEV 184 Query: 354 EIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLV 413 EI V + K C + + L G +GV + + R + Sbjct: 185 EI----VGIKETQKSTC-------TGVEMFRKLLDEGRAGENVGVLLR---GIKREEIER 230 Query: 414 GQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATG- 472 GQV+ G + +T E ++L K +G + K + T T Sbjct: 231 GQVLAKPGTIKP-HTKFESEVYIL-----SKDEGGRHTPFFKGYRPQFYFRTTDVTGTIE 284 Query: 473 ---ARVVAVKADMARLQLTS--PACTEINEKIALSRRIEKHWRLIGWATIKK 519 + + D ++ +T P + + A+ R R +G + K Sbjct: 285 LPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAI--REGG--RTVGAGVVAK 332 >1ZUN-B nrPDB Length = 434 Score = 200 bits (509), Expect = 1e-51, Method: Composition-based stats. Identities = 78/363 (21%), Positives = 131/363 (36%), Gaps = 71/363 (19%) Query: 96 NRQATINIGTIGHVAHGKSTVVRAI---SGVQTVRFKDELER--------NITIKLGYAN 144 R+ + T G+V GKST++ + S + + + R + L Sbjct: 20 ERKEMLRFLTCGNVDDGKSTLIGRLLHDSKMIYEDHLEAITRDSKKSGTTGDDVDLALLV 79 Query: 145 AKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTM 204 + +E YR F + K R D PGH+ M Sbjct: 80 DGLQAEREQGITIDVAYRYFSTAK------------------RKFIIADTPGHEQYTRNM 121 Query: 205 LSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM-REESALEHQ 263 +GA+ D A++L+ Q QT H ++ +KH+++ NK+DL +E E Sbjct: 122 ATGASTCDLAIILVDARYGV-QTQTRRHSYIASLLGIKHIVVAINKMDLNGFDERVFESI 180 Query: 264 K-SILKFIRG--TIADGAPIVPISAQLKYNIDAVNEF-----------IVKTIPVPPRDF 309 K LKF G VP+SA N+ +E I++T+ + Sbjct: 181 KADYLKFAEGIAFKPTTMAFVPMSALKGDNVVNKSERSPWYAGQSLMEILETVEIASDRN 240 Query: 310 MISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQ 369 R V VN+P G +A +G+ GDEI + P GK Sbjct: 241 YTDLRFPVQY---VNRPNLNFRGFAGTLA-----SGIVHKGDEIVVLP-------SGK-- 283 Query: 370 CKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTD 429 S + S+ + +L+ A PG + + + + + R D LV ++P + Sbjct: 284 ----SSRVKSIVTFEGELEQAGPGQAVTLTMEDEIDISRGDLLV-----HADNVPQVSDA 334 Query: 430 IEI 432 + Sbjct: 335 FDA 337 >4ZU9-A nrPDB Length = 582 Score = 195 bits (496), Expect = 3e-50, Method: Composition-based stats. Identities = 84/403 (20%), Positives = 146/403 (36%), Gaps = 81/403 (20%) Query: 100 TINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPD 159 I T GHV HGK+T+++ ++G+ T R +E +R ++I +G+A Sbjct: 3 YILFATAGHVDHGKTTLIKTLTGIDTDRLPEEKKRGLSIDIGFAYIDFPDINT------- 55 Query: 160 CYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIA 219 + +D PGH+ + ++G +L++ Sbjct: 56 ----------------------------RLEIIDVPGHERFIKNAIAGICSASGLILVVD 87 Query: 220 GNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAP 279 NE PQT EHL + +KH I + K+D + EE A ++ ++ F+ Sbjct: 88 PNEGI-MPQTIEHLRVAKSFGIKHGIAVLTKMDKVDEELAHIAEEELIAFLEKEEM-NME 145 Query: 280 IVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISP-RLIVIRSFDVNKPGAEIEDLKGGVA 338 IV +SA I+ + I K + P R+ V +F V G V Sbjct: 146 IVKVSAVTGQGIEDLKNSIKKLLESINNLNKHKPLRIFVDSAFVVKG--------YGTVL 197 Query: 339 GGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV 398 GS G K GD++ + P V S + + +K AV G I + Sbjct: 198 RGSCFEGEVKEGDKVVVEPIGVI-------------SRVRKMQNHGVFVKKAVAGERIAL 244 Query: 399 GTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEP 458 P + G ++ P Y +L VKT+ L+P Sbjct: 245 NL---PEVDAKKVKRGFLILK----PESYEK--------SNVLIVKTEID-------LKP 282 Query: 459 NEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIAL 501 ++ V G T ++ + + ++L A +K+ + Sbjct: 283 GKIYQVFFGMRETVGKISVIDKGIYLVRLKENAIVRRGDKLVV 325 >4D61-i nrPDB Length = 426 Score = 190 bits (481), Expect = 2e-48, Method: Composition-based stats. Identities = 67/361 (18%), Positives = 136/361 (37%), Gaps = 51/361 (14%) Query: 98 QATINIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIK---LGYANAKIYKCQ 151 + +N+ IGHV GKST+ + ++G+ R ++ ER K Y + + Q Sbjct: 1 KEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTNQ 60 Query: 152 EPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVM 211 E + DK + + R K H + +D PGH + M+ GA+ Sbjct: 61 E------------ERDKGKTVEVGRAYFETEKK---HFTILDAPGHKSFVPNMIGGASQA 105 Query: 212 DAALLLIAGNESCPQP------QTSEHLAAIEIMKLKHVIILQNKVDLM----REESALE 261 D A+L+I+ + + QT EH + +KH+I+L NK+D E E Sbjct: 106 DLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYEE 165 Query: 262 HQKSILKFIRGTIAD---GAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMIS-PRLIV 317 ++ ++ F++ + +P S N+ ++F I +P ++ + P Sbjct: 166 CKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFNR 225 Query: 318 IRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNI 377 + P + G V G + +G G ++ + P + Sbjct: 226 SVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMP-------------NKHNVEV 272 Query: 378 VSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLL 437 + + ++ + PG + + K + + L G ++ +L + + ++ Sbjct: 273 LGILSDDVETDTVAPGENLKIRLK---GIEEEEILPGFILCDPNNLCHSGRTFDAQIVII 329 Query: 438 R 438 Sbjct: 330 E 330 >5LZT-jj nrPDB Length = 637 Score = 188 bits (476), Expect = 7e-48, Method: Composition-based stats. Identities = 67/362 (18%), Positives = 137/362 (37%), Gaps = 51/362 (14%) Query: 97 RQATINIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIK---LGYANAKIYKC 150 ++ +N+ IGHV GKST+ + ++G+ R ++ ER K Y + + Sbjct: 209 KKEHVNVVFIGHVDAGKSTIGGQIMYLTGMVDKRTLEKYEREAKEKNRETWYLSWALDTN 268 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 QE + DK + + R K H + +D PGH + M+ GA+ Sbjct: 269 QE------------ERDKGKTVEVGRAYFETEKK---HFTILDAPGHKSFVPNMIGGASQ 313 Query: 211 MDAALLLIAGNESCPQP------QTSEHLAAIEIMKLKHVIILQNKVDLM----REESAL 260 D A+L+I+ + + QT EH + +KH+I+L NK+D E Sbjct: 314 ADLAVLVISARKGEFETGFEKGGQTREHAMLAKTAGVKHLIVLINKMDDPTVNWSNERYE 373 Query: 261 EHQKSILKFIRGTIAD---GAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMIS-PRLI 316 E ++ ++ F++ + +P S N+ ++F I +P ++ + P Sbjct: 374 ECKEKLVPFLKKVGFNPKKDIHFMPCSGLTGANLKEQSDFCPWYIGLPFIPYLDNLPNFN 433 Query: 317 VIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSN 376 + P + G V G + +G G ++ + P Sbjct: 434 RSVDGPIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMP-------------NKHNVE 480 Query: 377 IVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFL 436 ++ + ++ + PG + + K + + L G ++ +L + + + Sbjct: 481 VLGILSDDVETDTVAPGENLKIRLK---GIEEEEILPGFILCDPNNLCHSGRTFDAQIVI 537 Query: 437 LR 438 + Sbjct: 538 IE 539 >1R5O-A nrPDB Length = 467 Score = 181 bits (460), Expect = 5e-46, Method: Composition-based stats. Identities = 72/437 (16%), Positives = 148/437 (33%), Gaps = 80/437 (18%) Query: 98 QATINIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPT 154 + +NI IGHV GKST+ + ++G+ R +++ER + G + + + T Sbjct: 41 KEHVNIVFIGHVDAGKSTLGGNILFLTGMVDKRTMEKIEREAK-EAGKESWYLSWALDST 99 Query: 155 CPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAA 214 E + K + + R + R S +D PGH ++ M++GA+ D Sbjct: 100 SEERE--------KGKTVEVGRAYFETEH---RRFSLLDAPGHKGYVTNMINGASQADIG 148 Query: 215 LLLIAGNESCPQ------PQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQK---- 264 +L+I+ + QT EH + H++++ NK+D + + E K Sbjct: 149 VLVISARRGEFEAGFERGGQTREHAVLARTQGINHLVVVINKMDEPSVQWSEERYKECVD 208 Query: 265 ---SILKFIRGTIAD-GAPIVPISAQLKYNI--------------DAVNEFIVKTIPVPP 306 L+ + G + +P+SA N+ ++ E++ + Sbjct: 209 KLSMFLRRVAGYNSKTDVKYMPVSAYTGQNVKDRVDSSVCPWYQGPSLLEYLDSMTHL-E 267 Query: 307 RDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKG 366 R + + + G + G I G K + + P Sbjct: 268 RKVNAPFIMPIASKY----------KDLGTILEGKIEAGSIKKNSNVLVMP--------- 308 Query: 367 KIQCKPIFSNIVSL-FAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPN 425 + ++ ++ ++ G + + + D +D G V+ + + + Sbjct: 309 ----INQTLEVTAIYDEADEEISSSICGDQVRLRVRGDD----SDVQTGYVLTSTKNPVH 360 Query: 426 IYTDIEINYFLLR----RLLGVKTDGQKQAKVRKLEPNEVL----MVNIGSTATGARVVA 477 T +L G V ++ ++L N S Sbjct: 361 ATTRFIAQIAILELPSILTTGYSCVMHIHTAVEEVSFAKLLHKLDKTNRKSKKPPMFATK 420 Query: 478 VKADMARLQLTSPACTE 494 +A L+ +P C E Sbjct: 421 GMKIIAELETQTPVCME 437 >3J4J-A nrPDB Length = 569 Score = 166 bits (421), Expect = 2e-41, Method: Composition-based stats. Identities = 83/378 (21%), Positives = 142/378 (37%), Gaps = 80/378 (21%) Query: 25 IVEETEVVAQETQETQDADKPKKKVAFTGLEE-DGETEEEKRKREFEEGGGLPEQPLNPD 83 + +E + QE E D K + LEE D E E K + GL E+ + Sbjct: 9 LAKELGMETQELLELLDQMGVAYKSHASTLEEKDAEAVRELVKEQ----RGLQEKLAEEE 64 Query: 84 FSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYA 143 K P R+ + + +GHV HGK+T++ + R ++ IT +G Sbjct: 65 RRKSLP-------RRPPV-VVIMGHVDHGKTTLLDYLRK---SRIAEKEAGGITQHVGAF 113 Query: 144 NAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMST 203 K V F+D PGH+ + Sbjct: 114 EVK-------------------------------------TPQGTVVFIDTPGHEAFTTI 136 Query: 204 MLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEH 262 GA V D A+++IA ++ PQT E +A + K + NK+DL + + ++ Sbjct: 137 RQRGAKVADIAVIVIAADDGI-MPQTEEAIAHAKAAGAKLIF-AINKIDLPQADPEKVKR 194 Query: 263 QKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR--DFMISPRLIVIRS 320 Q F+ A ++PISA+ + + E I+ + D PR +++ S Sbjct: 195 QLMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILES 254 Query: 321 FDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSL 380 +++ G +A + G F++GD + V + G+I+ + Sbjct: 255 --------KLDKQAGIIANMLVQEGTFRVGDYV------VAGEAYGRIRA--------MM 292 Query: 381 FAEQNDLKFAVPGGLIGV 398 A+ N K A PG + V Sbjct: 293 DADGNQRKEAGPGSAVQV 310 >4KJZ-A nrPDB Length = 473 Score = 166 bits (419), Expect = 3e-41, Method: Composition-based stats. Identities = 73/343 (21%), Positives = 130/343 (37%), Gaps = 75/343 (21%) Query: 59 ETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVR 118 E + E + +E GL E+ + K P R+ + + +GHV HGK+T++ Sbjct: 39 EKDAEAVRELVKEQRGLQEKLAEEERRKSLP-------RRPPV-VVIMGHVDHGKTTLLD 90 Query: 119 AISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPG 178 + R ++ IT +G K Sbjct: 91 YLRK---SRIAEKEAGGITQHVGAFEVK-------------------------------- 115 Query: 179 CPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEI 238 V F+D PGH+ + GA V D A+++IA ++ PQT E +A + Sbjct: 116 -----TPQGTVVFIDTPGHEAFTTIRQRGAKVADIAVIVIAADDGI-MPQTEEAIAHAKA 169 Query: 239 MKLKHVIILQNKVDLMR-EESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEF 297 K + NK+DL + + ++ Q F+ A ++PISA+ + + E Sbjct: 170 AGAKLIF-AINKIDLPQADPEKVKRQLMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEM 228 Query: 298 IVKTIPVPPR--DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI 355 I+ + D PR +++ S +++ G +A + G F++GD + Sbjct: 229 ILLLAELEDYRADPNAEPRGVILES--------KLDKQAGIIANMLVQEGTFRVGDYV-- 278 Query: 356 RPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV 398 V + G+I+ + A+ N K A PG + V Sbjct: 279 ----VAGEAYGRIRA--------MMDADGNQRKEAGPGSAVQV 309 >5LZY-jj nrPDB Length = 710 Score = 165 bits (418), Expect = 4e-41, Method: Composition-based stats. Identities = 65/428 (15%), Positives = 139/428 (32%), Gaps = 56/428 (13%) Query: 96 NRQATINIGTIGHVAHGKSTVVRA---ISGVQTVRFKDELERNITIKLGYANAKIYKCQE 152 + +N+ IGHV GKST++ + G R + E+ + K G A+ + Sbjct: 282 GGKQLLNLVVIGHVDAGKSTLMGHMLYLLGNINKRTMHKYEQE-SKKAGKASFAYAWVLD 340 Query: 153 PTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMD 212 T E + + G + ++ +D PGH + M++GAA D Sbjct: 341 ETGEERERGVTMDV-----------GMTKFETTTKVITLMDAPGHKDFIPNMITGAAQAD 389 Query: 213 AALLLIAGNESCPQ------PQTSEHLAAIEIMKLKHVIILQNKVDLM--REESALEHQK 264 A+L++ + + QT EH + + + + + NK+D + ++E E Sbjct: 390 VAVLVVDASRGEFEAGFETGGQTREHGLLVRSLGVTQLAVAVNKMDQVNWQQERFQEITG 449 Query: 265 SILKFIR--GTIADGAPIVPISAQLKYNI------DAVNEFIVKTIPVPPRDFMISPRLI 316 + F++ G +P S N+ + ++ + D P+ Sbjct: 450 KLGHFLKQAGFKESDVGFIPTSGLSGENLITRSQSSELTKWYKGLCLLEQIDSFKPPQRS 509 Query: 317 VIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSN 376 + + F + + G G I G + GD + P Sbjct: 510 IDKPFRLCVSDVFKDQGSGFCITGKIEAGYIQTGDRLLAMP-------------PNETCT 556 Query: 377 IVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFL 436 + + + +A G + + + VG + T + Sbjct: 557 VKGITLHDEPVDWAAAGDHVSLTL---VGMDIIKINVGCIFCGPKVPIKACTRFRARILI 613 Query: 437 LRRLLGVKTDGQKQAKVRKLEPNEVL--MVNIGSTATGAR-------VVAVKADMARLQL 487 + + + + V+ ++++ + +TG + + + LQ Sbjct: 614 FNIEIPITKGFPVLLHYQTVSEPAVIKRLISVLNKSTGEVTKKKPKFLTKGQNALVELQT 673 Query: 488 TSPACTEI 495 P E+ Sbjct: 674 QRPIALEL 681 >4B44-A nrPDB Length = 363 Score = 164 bits (415), Expect = 7e-41, Method: Composition-based stats. Identities = 81/377 (21%), Positives = 142/377 (37%), Gaps = 78/377 (20%) Query: 25 IVEETEVVAQETQETQDADKPKKKVAFTGLEEDGETEEEKRKREFEEGGGLPEQPLNPDF 84 + +E + QE E D K + LEE + E + +E GL E+ + Sbjct: 9 LAKELGMETQELLELLDQMGVAYKSHASTLEE---KDAEAVRELVKEQRGLQEKLAEEER 65 Query: 85 SKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYAN 144 K P R+ + + +GHV HGK+T++ + R ++ IT +G Sbjct: 66 RKSLP-------RRPPV-VVIMGHVDHGKTTLLDYLRK---SRIAEKEAGGITQHVGAFE 114 Query: 145 AKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTM 204 K V F+D PGH+ + Sbjct: 115 VK-------------------------------------TPQGTVVFIDTPGHEAFTTIR 137 Query: 205 LSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQ 263 GA V D A+++IA ++ PQT E +A + K + NK+DL + + ++ Q Sbjct: 138 QRGAKVADIAVIVIAADDGI-MPQTEEAIAHAKAAGAKLIF-AINKIDLPQADPEKVKRQ 195 Query: 264 KSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR--DFMISPRLIVIRSF 321 F+ A ++PISA+ + + E I+ + D PR +++ S Sbjct: 196 LMERGFVPEEYGGDAIVIPISAKTGQGVQDLLEMILLLAELEDYRADPNAEPRGVILES- 254 Query: 322 DVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLF 381 +++ G +A + G F++GD + V + G+I+ + Sbjct: 255 -------KLDKQAGIIANMLVQEGTFRVGDYV------VAGEAYGRIRA--------MMD 293 Query: 382 AEQNDLKFAVPGGLIGV 398 A+ N K A PG + V Sbjct: 294 ADGNQRKEAGPGSAVQV 310 >3MCA-A nrPDB Length = 592 Score = 149 bits (376), Expect = 3e-36, Method: Composition-based stats. Identities = 80/486 (16%), Positives = 158/486 (32%), Gaps = 107/486 (22%) Query: 55 EEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKS 114 E D + E++K K++ NP P E N + +++ GHV GKS Sbjct: 144 ESDNQPEKKKIKKQ------------NPTDLVSVPEIFEQSNPKPVVHLVVTGHVDSGKS 191 Query: 115 TVVRAIS---GVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEIS 171 T++ I G R +L G + + T E + Sbjct: 192 TMLGRIMFELGEINSRSMQKLHNEAA-NSGKGSFSYAWLLD-TTEEERARGVTMDVASTT 249 Query: 172 PKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNES------CP 225 + + + D PGH +S M++GA+ D A+L++ +++ Sbjct: 250 FESDK----------KIYEIGDAPGHRDFISGMIAGASSADFAVLVVDSSQNNFERGFLE 299 Query: 226 QPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKSILKF----IRGTIADGAPI 280 QT EH + + + +++ NK+DLM E + K+I+ + G Sbjct: 300 NGQTREHAYLLRALGISEIVVSVNKLDLMSWSEDRFQEIKNIVSDFLIKMVGFKTSNVHF 359 Query: 281 VPISAQLKYNI--------------DAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKP 326 VPISA N+ + + + +P P + + RL + + Sbjct: 360 VPISAISGTNLIQKDSSDLYKWYKGPTLLSALDQLVP-PEKPYRKPLRLSIDDVY----- 413 Query: 327 GAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQND 386 + G + G ++ + V+ + ++ S+ S Sbjct: 414 ----RSPRSVTVTGRVEAGNVQVNQVLY----DVSSQEDAYVKNVIRNSDPSS------- 458 Query: 387 LKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTD 446 +AV G + + + G ++ + +RR+ + Sbjct: 459 -TWAVAGDTVTLQL---ADIEVNQLRPGDILSNYENP-------------VRRVRSFVAE 501 Query: 447 GQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACTEINEKIALSRRIE 506 Q + L++++G T T ++ T N++ SR I Sbjct: 502 IQTFDIHGPILSGSTLVLHLGRTVT--------------SVSLKIVTVNNKR---SRHIA 544 Query: 507 KHWRLI 512 R + Sbjct: 545 SRKRAL 550 >4CRN-P nrPDB Length = 430 Score = 139 bits (349), Expect = 3e-33, Method: Composition-based stats. Identities = 58/373 (15%), Positives = 128/373 (34%), Gaps = 68/373 (18%) Query: 96 NRQATINIGTIGHVAHGKSTV---VRAISGVQTVRFKDELERNITIKLGYANAKIYKCQE 152 + +++ +GHV GKST+ + ++G R ++ ER G + + Sbjct: 1 GGKDHVSLIFMGHVDAGKSTMGGNLLYLTGSVDKRTIEKYEREAK-DAGRQGWYLSWVMD 59 Query: 153 PTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMD 212 E + + + + R + +D PGH + +S M+ GA+ D Sbjct: 60 TNKEE--------RNDGKTIEVGKAYFETEK---RRYTILDAPGHKMYVSEMIGGASQAD 108 Query: 213 AALLLIAGNESCPQP------QTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSI 266 +L+I+ + + QT EH + + ++++ NK+D + E Sbjct: 109 VGVLVISARKGEYETGFERGGQTREHALLAKTQGVNKMVVVVNKMDDPTVNWSKERYDQC 168 Query: 267 LKFIRGT-------IADGAPIVPISAQLKYNI--------------DAVNEFIVKTIPVP 305 + + I +P+S N+ + E++ V Sbjct: 169 VSNVSNFLRAIGYNIKTDVVFMPVSGYSGANLKDHVDPKECPWYTGPTLLEYLDTMNHV- 227 Query: 306 PRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDK 365 + +P ++ I + G + G I +G K G + P +K Sbjct: 228 -DRHINAPFMLPIAA---------KMKDLGTIVEGKIESGHIKKGQSTLLMP------NK 271 Query: 366 GKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPN 425 ++ + I++ +N++ A+ G + + K + D G V+ + + Sbjct: 272 TAVEIQNIYNET------ENEVDMAMCGEQVKLRIK---GVEEEDISPGFVLTSPKNPIK 322 Query: 426 IYTDIEINYFLLR 438 T ++ Sbjct: 323 SVTKFVAQIAIVE 335 >3IZQ-1 nrPDB Length = 611 Score = 135 bits (339), Expect = 6e-32, Method: Composition-based stats. Identities = 67/401 (16%), Positives = 139/401 (34%), Gaps = 65/401 (16%) Query: 55 EEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKS 114 E +GE +++ + +P +P P +SA + + ++ +GHV GKS Sbjct: 127 ERNGEEANDEKTVQRYYKTTVPTKPKKPH-----DISAFVKSALPHLSFVVLGHVDAGKS 181 Query: 115 TVVRAISG---VQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEIS 171 T++ + + +L+R + +G ++ K + T E + S Sbjct: 182 TLMGRLLYDLNIVNQSQLRKLQRE-SETMGKSSFKFAWIMDQTNEERE-RGVTVSICTSH 239 Query: 172 PKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQ----- 226 R + VD PGH + + G + D A+L + + + + Sbjct: 240 FSTHRAN----------FTIVDAPGHRDFVPNAIMGISQADMAILCVDCSTNAFESGFDL 289 Query: 227 -PQTSEHLAAIEIMKLKHVIILQNKVDLMR--EESALEHQKSILKFI--RGTIADGAPIV 281 QT EH+ + + ++II NK+D + ++ E + +L ++ G D V Sbjct: 290 DGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLLPYLVDIGFFEDNINWV 349 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVI---RSFDVNKPGAEIEDLKG--- 335 PIS + + E+ + R + P L+ +F ++K I Sbjct: 350 PISGFSGEGVYKI-EYTDE-----VRQWYNGPNLMSTLENAAFKISKENEGINKDDPFLF 403 Query: 336 ---------------GVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSL 380 + G + +G + G+ + I P ++ I K + Sbjct: 404 SVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYP-----SEQSCIVDKIQVGSQQGQ 458 Query: 381 FAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKG 421 + A+ G + + + D G + + Sbjct: 459 STNHEETDVAIKGDFVTLKLRKAY---PEDIQNGDLAASVD 496 >3P27-A nrPDB Length = 483 Score = 132 bits (331), Expect = 4e-31, Method: Composition-based stats. Identities = 59/357 (16%), Positives = 121/357 (33%), Gaps = 60/357 (16%) Query: 99 ATINIGTIGHVAHGKSTVVRAISG---VQTVRFKDELERNITIKLGYANAKIYKCQEPTC 155 ++ +GHV GKST++ + + +L+R + +G ++ K + T Sbjct: 32 PHLSFVVLGHVDAGKSTLMGRLLYDLNIVNQSQLRKLQRE-SETMGKSSFKFAWIMDQTN 90 Query: 156 PEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAAL 215 E + S R + VD PGH + + G + D A+ Sbjct: 91 EERE-RGVTVSICTSHFSTHRAN----------FTIVDAPGHRDFVPNAIMGISQADMAI 139 Query: 216 LLIAGNESCPQ------PQTSEHLAAIEIMKLKHVIILQNKVDLMR--EESALEHQKSIL 267 L + + + + QT EH+ + + ++II NK+D + ++ E + +L Sbjct: 140 LCVDCSTNAFESGFDLDGQTKEHMLLASSLGIHNLIIAMNKMDNVDWSQQRFEEIKSKLL 199 Query: 268 KFI--RGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVI---RSFD 322 ++ G D VPIS + + E+ + R + P L+ +F Sbjct: 200 PYLVDIGFFEDNINWVPISGFSGEGVYKI-EYTDE-----VRQWYNGPNLMSTLENAAFK 253 Query: 323 VNKPGAEIEDLKG------------------GVAGGSILNGVFKLGDEIEIRPGIVTKDD 364 ++K I + G + +G + G+ + I P + Sbjct: 254 ISKENEGINKDDPFLFSVLEIIPSKKTSNDLALVSGKLESGSIQPGESLTIYP-----SE 308 Query: 365 KGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKG 421 + I K + + A+ G + + + D G + + Sbjct: 309 QSCIVDKIQVGSQQGQSTNHEETDVAIKGDFVTLKLRKAY---PEDIQNGDLAASVD 362 >2LKD-A nrPDB Length = 178 Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats. Identities = 42/217 (19%), Positives = 81/217 (37%), Gaps = 45/217 (20%) Query: 91 SAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKC 150 + ++ R + I +GHV HGK+T++ AI + ++ IT +G Sbjct: 1 GSHMVERPPVVTI--MGHVDHGKTTLLDAIR---HSKVTEQEAGGITQHIG--------- 46 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 Y+ +DK ++F+D PGH+ + GA V Sbjct: 47 ---------AYQVTVNDK-------------------KITFLDTPGHEAFTTMRARGAQV 78 Query: 211 MDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMRE-ESALEHQKSILKF 269 D +L++A ++ PQT E + + + +I+ NK+D + + Sbjct: 79 TDIVILVVAADDGV-MPQTVEAINHAKAANVP-IIVAINKMDKPEANPDRVMQELMEYNL 136 Query: 270 IRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPP 306 + +SA+ K +D + E I+ + Sbjct: 137 VPEEWGGDTIFCKLSAKTKEGLDHLLEMILLVSEMEE 173 >1G7S-A nrPDB Length = 594 Score = 116 bits (289), Expect = 3e-26, Method: Composition-based stats. Identities = 65/367 (17%), Positives = 123/367 (33%), Gaps = 76/367 (20%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK+T++ I G + IT +G + E C D + Sbjct: 8 VSVLGHVDHGKTTLLDHIRGSAVASRE---AGGITQHIGATEIPM-DVIEGICG--DFLK 61 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 F R PG + F+D PGH+ + G A+ D A+L++ NE Sbjct: 62 KF---------SIRETLPGLF-------FIDTPGHEAFTTLRKRGGALADLAILIVDINE 105 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDL----------------------MREESAL 260 +PQT E L + + + ++ NK+D ++++ Sbjct: 106 GF-KPQTQEALNILRMYRTPF-VVAANKIDRIHGWRVHEGRPFMETFSKQDIQVQQKLDT 163 Query: 261 EHQKSILKFIRG-----------TIADGAPIVPISAQLKYNIDAVNEFIV----KTIPVP 305 + + + K A I+PISA I + ++ + + Sbjct: 164 KVYELVGKLHEEGFESERFDRVTDFASQVSIIPISAITGEGIPELLTMLMGLAQQYLREQ 223 Query: 306 PRDFMISP-RLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDD 364 + SP R ++ + G I+ + I +G+ + D I + Sbjct: 224 LKIEEDSPARGTILEVKEETGLGMTIDAV--------IYDGILRKDDTIAMMTSKDVIST 275 Query: 365 KGKIQCKPI-FSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHL 423 + + KP + + + V I + V P + D + G + Sbjct: 276 RIRSLLKPRPLEEMRESRKKFQKVDEVVAAAGIKI---VAPGID--DVMAGSPLRVVTDP 330 Query: 424 PNIYTDI 430 + +I Sbjct: 331 EKVREEI 337 >6GB2-BC nrPDB Length = 657 Score = 112 bits (279), Expect = 4e-25, Method: Composition-based stats. Identities = 60/362 (16%), Positives = 114/362 (31%), Gaps = 79/362 (21%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK+T++ Q + IT +G + + Sbjct: 113 VTIMGHVDHGKTTLLDKFRKTQVAAVE---TGGITQHIGAFLVSLPSGE----------- 158 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 ++F+D PGH + GA V D +L++A ++ Sbjct: 159 -------------------------KITFLDTPGHAAFSAMRARGAQVTDIVVLVVAADD 193 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKSILKFIRGTIADGAPIV 281 QT E + + ++ +I+ NK D + ++ + + V Sbjct: 194 GV-MKQTVESIQHAKDAQVP-IILAVNKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAV 251 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPP--RDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAG 339 P+SA N+ A+ E V + D VI SF +G V Sbjct: 252 PVSALTGDNLMALAEATVALAEMLELKADPNGPVEGTVIESFTDKG--------RGLVTT 303 Query: 340 GSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV- 398 I G + G + V K++ + + A P +G+ Sbjct: 304 AIIQRGTLRKGSVL------VAGKCWAKVR--------LMFDENGKTIDEAYPSMPVGIT 349 Query: 399 GTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEP 458 G + P+ G+ + P ++ + + GQ+ K+ + + Sbjct: 350 GWRDLPS-------AGEEILEVESEPRAREVVDWRKYEQE-----QEKGQEDLKIIEEKR 397 Query: 459 NE 460 E Sbjct: 398 KE 399 >5FG3-A nrPDB Length = 623 Score = 108 bits (268), Expect = 9e-24, Method: Composition-based stats. Identities = 76/427 (17%), Positives = 140/427 (32%), Gaps = 89/427 (20%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK+T++ I + IT +G + ++ P Sbjct: 19 VVVLGHVDHGKTTLLDKIRRTAVAA---KEAGGITQHIGASIVPADVIEKIAEPL----- 70 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 K I K PG F+D PGH++ + G +V D A+L++ E Sbjct: 71 ----KKVIPVKLVIPGLL----------FIDTPGHELFSNLRRRGGSVADFAILVVDIME 116 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM-----------------REESALEHQKS 265 +PQT E L ++ ++ +I NK+D + ++ E + Sbjct: 117 GF-KPQTYEALELLKERRVPFLIAA-NKIDRIPGWKPNPDAPFIETIRRQDPKVREILEQ 174 Query: 266 ILKFIRGTIAD----------------GAPIVPISAQLKYNIDAVNEFI----VKTIPVP 305 + I G + + IVP+SA+ I + + + Sbjct: 175 RVYEIVGKMYEAGLPAELFTRIKDFRRKIAIVPVSARTGEGIPELLAVLAGLTQTYLKER 234 Query: 306 PRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKD 363 R + +V+ ++ G V I +GV K D I + R G + Sbjct: 235 LRYAEGPAKGVVLEVKEMQG--------FGTVVDAVIYDGVLKKEDIIVVGGREGPIVTR 286 Query: 364 DKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHL 423 + + P+ +I S A + + + P L D + G + A Sbjct: 287 VRALLMPAPLQ-DIRSREARFVQVDRVYAAAGVRIAA---PGLD--DVIAGSPIYAAESE 340 Query: 424 PNIY----------TDIEINYFLLRRLLGVKTDGQKQAKVRKLEPN--EVLMVNIGSTAT 471 ++ + ++ T G +A V L V + +IG + Sbjct: 341 EEARKLMEAVQREIEELRFRTENIGVVVKADTLGTLEALVEALRRRGVPVRLADIGPVSR 400 Query: 472 GARVVAV 478 + A Sbjct: 401 SDVLDAA 407 >2YWH-A nrPDB Length = 600 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 63/330 (19%), Positives = 113/330 (34%), Gaps = 49/330 (14%) Query: 95 INRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPT 154 + ++ N I HV HGKST+ + T + +R + + +E Sbjct: 1 MEQKNVRNFCIIAHVDHGKSTLADRLLEY-TGAISEREKREQLLDT------LDVERERG 53 Query: 155 CPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAA 214 + + R + + +D PGH + A + A Sbjct: 54 IT-------------VKMQAVRMFYKAKDGNTYKLHLIDTPGHVDFSYEVSRALAACEGA 100 Query: 215 LLLIAGNESCPQPQTSEHLAAIEIMKLKHVII-LQNKVDLMREESALEHQKSILKFIRGT 273 LLLI ++ + QT + ++ VII + NK+DL + ++ K ++ + G Sbjct: 101 LLLIDASQGI-EAQTV--ANFWKAVEQDLVIIPVINKIDLPSAD--VDRVKKQIEEVLGL 155 Query: 274 IADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDL 333 + A + SA+ I+ + E IV IP P D + ++ S+ + Sbjct: 156 DPEEA--ILASAKEGIGIEEILEAIVNRIPPPKGDPQKPLKALIFDSY--------YDPY 205 Query: 334 KGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPG 393 +G VA I +G K GD+I + + P + L A Sbjct: 206 RGAVAFVRIFDGEVKPGDKIMLMSTGKEYEVTEVGAQTPKMTKFDKLSAGDV-------- 257 Query: 394 GLIGVGTKVDPTLCRADRLVGQVVGAKGHL 423 G I K D +G + + Sbjct: 258 GYIAASIKDV-----RDIRIGDTITHAKNP 282 >3IZY-P nrPDB Length = 537 Score = 106 bits (265), Expect = 2e-23, Method: Composition-based stats. Identities = 48/299 (16%), Positives = 93/299 (31%), Gaps = 66/299 (22%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK+T++ + Q + IT +G + + Sbjct: 7 VTIMGHVDHGKTTLLDKLRKTQVAAME---AGGITQHIGAFLVSLPSGE----------- 52 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 ++F+D PGH + G V D +L++A ++ Sbjct: 53 -------------------------KITFLDTPGHAAFSAMRARGTQVTDIVILVVAADD 87 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKSILKFIRGTIADGAPIV 281 QT E + + + +++ NK D + ++ + + V Sbjct: 88 GV-MKQTVESIQHAKDAHVP-IVLAINKCDKAEADPEKVKKELLAYDVVCEDYGGDVQAV 145 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPP--RDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAG 339 +SA N+ A+ E + + D + VI SF +G V Sbjct: 146 HVSALTGENMMALAEATIALAEMLELKADPTGAVEGTVIESFTDKG--------RGPVTT 197 Query: 340 GSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGV 398 I G + G +V K++ + + A P +G+ Sbjct: 198 AIIQRGTLRKGS------ILVAGKSWAKVR--------LMFDENGRAVNEAYPSMPVGI 242 >1ZO1-I nrPDB Length = 501 Score = 103 bits (256), Expect = 2e-22, Method: Composition-based stats. Identities = 51/294 (17%), Positives = 99/294 (33%), Gaps = 69/294 (23%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK++++ I + + IT +G Sbjct: 7 VTIMGHVDHGKTSLLEYIR---STKVASGEAGGITQHIG--------------------- 42 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + + ++F+D PGH S GA D +L++A ++ Sbjct: 43 ----AYHVETENGM------------ITFLDTPGHAAFTSMRARGAQATDIVVLVVAADD 86 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKSILKFIRGTIADGAPIV 281 PQT E + + V++ NK+D + ++++ S + + V Sbjct: 87 GV-MPQTIEAIQHAKAA-QVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFV 144 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPPRDFMIS--PRLIVIRSFDVNKPGAEIEDLKGGVAG 339 +SA+ ID + + I+ V + VI SF ++ +G VA Sbjct: 145 HVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESF--------LDKGRGPVAT 196 Query: 340 GSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAE-QNDLKFAVP 392 + G GD + C + + ++ E ++ A P Sbjct: 197 VLVREGTLHKGDIV---------------LCGFEYGRVRAMRNELGQEVLEAGP 235 >5YT0-A nrPDB Length = 364 Score = 102 bits (254), Expect = 3e-22, Method: Composition-based stats. Identities = 62/336 (18%), Positives = 114/336 (33%), Gaps = 72/336 (21%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK+T++ I + IT +G + ++ P Sbjct: 19 VVVLGHVDHGKTTLLDKIRRTAVAA---KEAGGITQHIGASIVPADVIEKIAEPL----- 70 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 K I K PG F+D PGH++ + G +V D A+L++ E Sbjct: 71 ----KKVIPVKLVIPGLL----------FIDTPGHELFSNLRRRGGSVADFAILVVDIME 116 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM-----------------REESALEHQKS 265 +PQT E L ++ ++ +I NK+D + ++ E + Sbjct: 117 GF-KPQTYEALELLKERRVPFLIAA-NKIDRIPGWKPNPDAPFIETIRRQDPKVREILEQ 174 Query: 266 ILKFIRGTIAD----------------GAPIVPISAQLKYNIDAVNEFI----VKTIPVP 305 + I G + + IVP+SA+ I + + + Sbjct: 175 RVYEIVGKMYEAGLPAELFTRIKDFRRKIAIVPVSARTGEGIPELLAVLAGLTQTYLKER 234 Query: 306 PRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKD 363 R + +V+ ++ G V I +GV K D I + R G + Sbjct: 235 LRYAEGPAKGVVLEVKEMQG--------FGTVVDAVIYDGVLKKEDIIVVGGREGPIVTR 286 Query: 364 DKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVG 399 + + P+ +I S A + + + Sbjct: 287 VRALLMPAPLQ-DIRSREARFVQVDRVYAAAGVRIA 321 >3CB4-D nrPDB Length = 599 Score = 102 bits (254), Expect = 4e-22, Method: Composition-based stats. Identities = 53/257 (20%), Positives = 97/257 (37%), Gaps = 38/257 (14%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 N I H+ HGKST+ +R I I G ++ ++ + Sbjct: 6 NFSIIAHIDHGKSTLS---------------DRIIQICGGLSDREMEAQVLDSMDLERER 50 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + ++ + ++F+D PGH + A + ALL++ Sbjct: 51 GITIKAQSVTLDYKASDGET-----YQLNFIDTPGHVDFSYEVSRSLAACEGALLVVDAG 105 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM--REESALEHQKSILKFIRGTIADGAP 279 + + QT + M L+ V+ + NK+DL E E + I+ D Sbjct: 106 QGV-EAQTLANCYTAMEMDLE-VVPVLNKIDLPAADPERVAEEIEDIVGI------DATD 157 Query: 280 IVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAG 339 V SA+ + V E +V+ IP P D + ++I S+ ++ G V+ Sbjct: 158 AVRCSAKTGVGVQDVLERLVRDIPPPEGDPEGPLQALIIDSW--------FDNYLGVVSL 209 Query: 340 GSILNGVFKLGDEIEIR 356 I NG + GD++++ Sbjct: 210 IRIKNGTLRKGDKVKVM 226 >3JCN-b nrPDB Length = 890 Score = 99.6 bits (246), Expect = 3e-21, Method: Composition-based stats. Identities = 51/294 (17%), Positives = 99/294 (33%), Gaps = 69/294 (23%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GHV HGK++++ I + + IT +G Sbjct: 394 VTIMGHVDHGKTSLLDYIR---STKVASGEAGGITQHIG--------------------- 429 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + + ++F+D PGH S GA D +L++A ++ Sbjct: 430 ----AYHVETENGM------------ITFLDTPGHAAFTSMRARGAQATDIVVLVVAADD 473 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKSILKFIRGTIADGAPIV 281 PQT E + + V++ NK+D + ++++ S + + V Sbjct: 474 GV-MPQTIEAIQHAKAA-QVPVVVAVNKIDKPEADPDRVKNELSQYGILPEEWGGESQFV 531 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPPRDFMIS--PRLIVIRSFDVNKPGAEIEDLKGGVAG 339 +SA+ ID + + I+ V + VI SF ++ +G VA Sbjct: 532 HVSAKAGTGIDELLDAILLQAEVLELKAVRKGMASGAVIESF--------LDKGRGPVAT 583 Query: 340 GSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAE-QNDLKFAVP 392 + G GD + C + + ++ E ++ A P Sbjct: 584 VLVREGTLHKGDIV---------------LCGFEYGRVRAMRNELGQEVLEAGP 622 >5IMR-C nrPDB Length = 610 Score = 99.2 bits (245), Expect = 4e-21, Method: Composition-based stats. Identities = 49/324 (15%), Positives = 100/324 (30%), Gaps = 46/324 (14%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 N I HV HGKST+ +R + + ++ ++ + + Sbjct: 11 NFSIIAHVDHGKSTLA---------------DRILELTHAVSDREMREQFLDSLELERER 55 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + +D PGH + A ++ LL++ + Sbjct: 56 GITIKASAVRVTYRAKDGEEYV-----FHLIDTPGHVDFTYEVSRALAAVEGVLLVVDAS 110 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIV 281 + + +T +I + NK+DL ++ + G AD A Sbjct: 111 QGV-EAETLAKFYMALEHG-HVIIPVINKIDLPNARPLE--VALEVEEVLGLPADEAIF- 165 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGS 341 S + ++ + E IV+ IP P D + ++ S + +G + Sbjct: 166 -ASGKTGEGVEEILEAIVQRIPPPKGDPEAPLKALIFDSV--------YDAYQGVIPYLR 216 Query: 342 ILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTK 401 + G + GD I I + + + +F+ + A+ G +G Sbjct: 217 LFEGRVRPGDRIRI----YSTGKEFTVDKVGVFTPQGLVAT------EALEAGEVGWLVA 266 Query: 402 VDPTLCRADRLVGQVVGAKGHLPN 425 + D VG + Sbjct: 267 AIRDI--HDVQVGDTITLADRPTP 288 >5J8B-z nrPDB Length = 679 Score = 98.8 bits (244), Expect = 5e-21, Method: Composition-based stats. Identities = 49/324 (15%), Positives = 100/324 (30%), Gaps = 46/324 (14%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 N I HV HGKST+ +R + + ++ ++ + + Sbjct: 80 NFSIIAHVDHGKSTLA---------------DRILELTHAVSDREMREQFLDSLELERER 124 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + +D PGH + A ++ LL++ + Sbjct: 125 GITIKASAVRVTYRAKDGEEYV-----FHLIDTPGHVDFTYEVSRALAAVEGVLLVVDAS 179 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIV 281 + + +T +I + NK+DL ++ + G AD A Sbjct: 180 QGV-EAETLAKFYMALEHG-HVIIPVINKIDLPNARPLE--VALEVEEVLGLPADEAIF- 234 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGS 341 S + ++ + E IV+ IP P D + ++ S + +G + Sbjct: 235 -ASGKTGEGVEEILEAIVQRIPPPKGDPEAPLKALIFDSV--------YDAYQGVIPYLR 285 Query: 342 ILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTK 401 + G + GD I I + + + +F+ + A+ G +G Sbjct: 286 LFEGRVRPGDRIRI----YSTGKEFTVDKVGVFTPQGLVAT------EALEAGEVGWLVA 335 Query: 402 VDPTLCRADRLVGQVVGAKGHLPN 425 + D VG + Sbjct: 336 AIRDI--HDVQVGDTITLADRPTP 357 >5A9Z-CA nrPDB Length = 593 Score = 95.3 bits (235), Expect = 6e-20, Method: Composition-based stats. Identities = 54/303 (17%), Positives = 101/303 (33%), Gaps = 37/303 (12%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NI I HV HGK+T+V + L+++ T + A+ + + Sbjct: 7 NIAIIAHVDHGKTTLVDKL-----------LQQSGTFD---SRAETQERVMDSNDLEKER 52 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 K + K ++ VD PGH + +++D+ LL++ Sbjct: 53 GITILAKNTAAI----------KWDYRINIVDTPGHADFGGEVERVMSMVDSVLLVVDAF 102 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM---REESALEHQKSILKFIRGTIADGA 278 + P PQT LK +++ NKVD + + + Sbjct: 103 DG-PMPQTRFVTKKAFAYGLKPIVV-INKVDRPGARPDWVVDQVFDLFVNLDATDEQLDF 160 Query: 279 PIVPISAQLKYNIDAVNEFIVKTIPV--PPRDFMISPRLIVIRSFDVNKPGAEIEDLKGG 336 IV SA + P+ D + +P + + F + + G Sbjct: 161 AIVYASALNGIAGLDHEDMAEDMTPLYQAIVDHVPAPDVDLDGPFQMQISQLDYNSYVGV 220 Query: 337 VAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLI 396 + G I G K ++ I D +GK + + + L E+ + A G ++ Sbjct: 221 IGIGRIKRGKVKPNQQVTII------DSEGKTRNAKVGKVLGHLGLERIETDLAEAGDIV 274 Query: 397 GVG 399 + Sbjct: 275 AIT 277 >4NCL-A nrPDB Length = 457 Score = 93.4 bits (230), Expect = 2e-19, Method: Composition-based stats. Identities = 52/325 (16%), Positives = 108/325 (33%), Gaps = 71/325 (21%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I ++ IT ++G + ++ T Sbjct: 15 ILGHVDTGKTKLLDKIRQTNV---QEGEAGGITQQIGATYFPVEAIKQKTA--------- 62 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 +K+ + + PG +D PGH+ + G+++ + A+L++ Sbjct: 63 VVNKDGKFEFKVPGLL----------IIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGL 112 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---------- 274 +PQT E L + K ++ NK+D + +E+ F Sbjct: 113 -EPQTIESLRLLRERKTPF-VVALNKIDRLYGWKKIENNGFRESFALQNKAVQNEFRNRL 170 Query: 275 -----------------------ADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRD--- 308 A +VP SA I + + IV+ Sbjct: 171 DQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDMLKLIVQLCQERMASSLM 230 Query: 309 FMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKG 366 ++ + V+ + G I+ + + NG+ + GD I + G + + + Sbjct: 231 YLSELQATVLEVKAIEGFGVTIDVI--------LSNGILREGDRIVLCGLEGPIKTNIRA 282 Query: 367 KIQCKPIFS-NIVSLFAEQNDLKFA 390 + P+ I + ++K A Sbjct: 283 LLTPAPMRELRIKGQYIHHKEVKAA 307 >4N3G-A nrPDB Length = 603 Score = 93.0 bits (229), Expect = 3e-19, Method: Composition-based stats. Identities = 52/325 (16%), Positives = 108/325 (33%), Gaps = 71/325 (21%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I ++ IT ++G + ++ T Sbjct: 15 ILGHVDTGKTKLLDKIRQTNV---QEGEAGGITQQIGATYFPVEAIKQKTA--------- 62 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 +K+ + + PG +D PGH+ + G+++ + A+L++ Sbjct: 63 VVNKDGKFEFKVPGLL----------IIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGL 112 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---------- 274 +PQT E L + K ++ NK+D + +E+ F Sbjct: 113 -EPQTIESLRLLRERKTPF-VVALNKIDRLYGWKKIENNGFRESFALQNKAVQNEFRNRL 170 Query: 275 -----------------------ADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRD--- 308 A +VP SA I + + IV+ Sbjct: 171 DQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDMLKLIVQLCQERMASSLM 230 Query: 309 FMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKG 366 ++ + V+ + G I+ + + NG+ + GD I + G + + + Sbjct: 231 YLSELQATVLEVKAIEGFGVTIDVI--------LSNGILREGDRIVLCGLEGPIKTNIRA 282 Query: 367 KIQCKPIFS-NIVSLFAEQNDLKFA 390 + P+ I + ++K A Sbjct: 283 LLTPAPMRELRIKGQYIHHKEVKAA 307 >4UJC-AB nrPDB Length = 627 Score = 91.8 bits (226), Expect = 6e-19, Method: Composition-based stats. Identities = 78/444 (17%), Positives = 145/444 (32%), Gaps = 100/444 (22%) Query: 56 EDGETEEEK---------RKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTI 106 +D T+EE+ KR E + + L I + Sbjct: 3 DDDRTKEERAYDKAKRRIEKRRLEHSKNVNTEKLRAPV------------------ICVL 44 Query: 107 GHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSFKS 166 GHV GK+ ++ + +D IT ++G N + E T + R Sbjct: 45 GHVDTGKTKILDKLRHTHV---QDGEAGGITQQIGATNVPLEAINEQTKMIKNFDRENVR 101 Query: 167 DKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQ 226 + +D PGH+ + G+++ D A+L++ + Sbjct: 102 IPGML-------------------IIDTPGHESFSNLRNRGSSLCDIAILVVDIMHGL-E 141 Query: 227 PQTSEHLAAIEIMKLKHVIILQNKVDLMRE---------------------ESALEHQKS 265 PQT E + ++ K + + NK+D + + + E K+ Sbjct: 142 PQTIESINLLKSKKCPFI-VALNKIDRLYDWKKSPDSDVAATLKKQKKNTKDEFEERAKA 200 Query: 266 ILKFIRGTIADGA------------PIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISP 313 I+ + A +VP SA + ++ +V+ M+S Sbjct: 201 IIVEFAQQGLNAALFYENKDPRTFVSLVPTSAHTGDGMGSLIYLLVELTQT-----MLSK 255 Query: 314 RLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGI---VTKDDKGKIQC 370 RL + G ++NG K GD I I PG+ + +G + Sbjct: 256 RLAHCEELRAQVMEVKALPGMGTTIDVILINGRLKEGDTI-IVPGVEGPIVTQIRGLLLP 314 Query: 371 KPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDI 430 P+ V E++ A G I +G ++ TL L V + +P + ++ Sbjct: 315 PPMKELRVKNQYEKHKEVEAAQGVKI-LGKDLEKTLAGLPLL---VAYKEDEIPVLKDEL 370 Query: 431 EINYFLLRRLLGVKTDGQKQAKVR 454 L++ L +K V+ Sbjct: 371 ---IHELKQTLNAIKLEEKGVYVQ 391 >4TN1-B nrPDB Length = 345 Score = 88.8 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 52/325 (16%), Positives = 108/325 (33%), Gaps = 71/325 (21%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I ++ IT ++G + ++ T Sbjct: 15 ILGHVRTGKTKLLDKIRQTNV---QEGEAGGITQQIGATYFPVEAIKQKTA--------- 62 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 +K+ + + PG +D PGH+ + G+++ + A+L++ Sbjct: 63 VVNKDGKFEFKVPGLL----------IIDTPGHESFSNLRSRGSSLCNIAILVVDIMHGL 112 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI---------- 274 +PQT E L + K ++ NK+D + +E+ F Sbjct: 113 -EPQTIESLRLLRERKTPF-VVALNKIDRLYGWKKIENNGFRESFALQNKAVQNEFRNRL 170 Query: 275 -----------------------ADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRD--- 308 A +VP SA I + + IV+ Sbjct: 171 DQVKLQFAEQGFNSELFYENKNFARYVSLVPTSAHTGEGIPDMLKLIVQLCQERMASSLM 230 Query: 309 FMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKG 366 ++ + V+ + G I+ + + NG+ + GD I + G + + + Sbjct: 231 YLSELQATVLEVKAIEGFGVTIDVI--------LSNGILREGDRIVLCGLEGPIKTNIRA 282 Query: 367 KIQCKPIFS-NIVSLFAEQNDLKFA 390 + P+ I + ++K A Sbjct: 283 LLTPAPMRELRIKGQYIHHKEVKAA 307 >4NCF-A nrPDB Length = 457 Score = 88.8 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 50/322 (15%), Positives = 104/322 (32%), Gaps = 65/322 (20%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I + IT ++G I Sbjct: 15 ILGHVDTGKTKLLDKIRQTNV---QGGEAGGITQQIGATYFPIDAI------------KA 59 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 K+ + Q PG + +D PGH+ + G+++ + A+L+I Sbjct: 60 KTKVMAEYEKQTFDVPG-------LLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGL 112 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMRE---------------------ESALEHQ 263 Q QT E + + K ++ NK+D + + E Sbjct: 113 EQ-QTIESIKLLRDRKAPF-VVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRY 170 Query: 264 KSILKFIRGTIADG------------APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMI 311 I + + IVP SA + + +++ + Sbjct: 171 SKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKR-----M 225 Query: 312 SPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKGKIQ 369 S +L+ + + ++ + G + NG + GD I + G + + + + Sbjct: 226 SKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLT 285 Query: 370 CKPIFS-NIVSLFAEQNDLKFA 390 +P+ + S + ++K A Sbjct: 286 PQPLRELRLKSEYVHHKEVKAA 307 >4V8Y-CP nrPDB Length = 339 Score = 88.0 bits (216), Expect = 8e-18, Method: Composition-based stats. Identities = 50/322 (15%), Positives = 104/322 (32%), Gaps = 65/322 (20%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I + IT ++G I Sbjct: 10 ILGHVDTGKTKLLDKIRQTNV---QGGEAGGITQQIGATYFPIDAI------------KA 54 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 K+ + Q PG + +D PGH+ + G+++ + A+L+I Sbjct: 55 KTKVMAEYEKQTFDVPG-------LLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGL 107 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMRE---------------------ESALEHQ 263 Q QT E + + K ++ NK+D + + E Sbjct: 108 EQ-QTIESIKLLRDRKAPF-VVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRY 165 Query: 264 KSILKFIRGTIADG------------APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMI 311 I + + IVP SA + + +++ + Sbjct: 166 SKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKR-----M 220 Query: 312 SPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKGKIQ 369 S +L+ + + ++ + G + NG + GD I + G + + + + Sbjct: 221 SKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLT 280 Query: 370 CKPIFS-NIVSLFAEQNDLKFA 390 +P+ + S + ++K A Sbjct: 281 PQPLRELRLKSEYVHHKEVKAA 302 >3WBI-A nrPDB Length = 606 Score = 87.6 bits (215), Expect = 1e-17, Method: Composition-based stats. Identities = 50/322 (15%), Positives = 104/322 (32%), Gaps = 65/322 (20%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I + IT ++G I Sbjct: 14 ILGHVDTGKTKLLDKIRQTNV---QGGEAGGITQQIGATYFPIDAI------------KA 58 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 K+ + Q PG + +D PGH+ + G+++ + A+L+I Sbjct: 59 KTKVMAEYEKQTFDVPG-------LLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGL 111 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMRE---------------------ESALEHQ 263 Q QT E + + K ++ NK+D + + E Sbjct: 112 EQ-QTIESIKLLRDRKAPF-VVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRY 169 Query: 264 KSILKFIRGTIADG------------APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMI 311 I + + IVP SA + + +++ + Sbjct: 170 SKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKR-----M 224 Query: 312 SPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKGKIQ 369 S +L+ + + ++ + G + NG + GD I + G + + + + Sbjct: 225 SKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLT 284 Query: 370 CKPIFS-NIVSLFAEQNDLKFA 390 +P+ + S + ++K A Sbjct: 285 PQPLRELRLKSEYVHHKEVKAA 306 >4V8Z-CV nrPDB Length = 586 Score = 85.3 bits (209), Expect = 5e-17, Method: Composition-based stats. Identities = 50/322 (15%), Positives = 104/322 (32%), Gaps = 65/322 (20%) Query: 105 TIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRSF 164 +GHV GK+ ++ I + IT ++G I Sbjct: 10 ILGHVDTGKTKLLDKIRQTNV---QGGEAGGITQQIGATYFPIDAI------------KA 54 Query: 165 KSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESC 224 K+ + Q PG + +D PGH+ + G+++ + A+L+I Sbjct: 55 KTKVMAEYEKQTFDVPG-------LLVIDTPGHESFSNLRSRGSSLCNIAILVIDIMHGL 107 Query: 225 PQPQTSEHLAAIEIMKLKHVIILQNKVDLMRE---------------------ESALEHQ 263 Q QT E + + K ++ NK+D + + E Sbjct: 108 EQ-QTIESIKLLRDRKAPF-VVALNKIDRLYDWKAIPNNSFRDSFAKQSRAVQEEFQSRY 165 Query: 264 KSILKFIRGTIADG------------APIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMI 311 I + + IVP SA + + +++ + Sbjct: 166 SKIQLELAEQGLNSELYFQNKNMSKYVSIVPTSAVTGEGVPDLLWLLLELTQKR-----M 220 Query: 312 SPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEI--RPGIVTKDDKGKIQ 369 S +L+ + + ++ + G + NG + GD I + G + + + + Sbjct: 221 SKQLMYLSHVEATILEVKVVEGFGTTIDVILSNGYLREGDRIVLCGMNGPIVTNIRALLT 280 Query: 370 CKPIFS-NIVSLFAEQNDLKFA 390 +P+ + S + ++K A Sbjct: 281 PQPLRELRLKSEYVHHKEVKAA 302 >5KCS-1w nrPDB Length = 639 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 55/152 (36%), Gaps = 24/152 (15%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 INIG + HV GK+T+ ++ +LG + + Sbjct: 4 INIGVLAHVDAGKTTLTESL----------LYNSGAITELGSVD--KGTTRTDNTLLERQ 51 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 S + + V+ +D PGH ++ + +V+D A+LLI+ Sbjct: 52 RGITIQTGITSFQWENT----------KVNIIDTPGHMDFLAEVYRSLSVLDGAILLISA 101 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVD 252 + Q QT A+ M + + NK+D Sbjct: 102 KDGV-QAQTRILFHALRKMGIPTIF-FINKID 131 >4V6V-A1 nrPDB Length = 639 Score = 81.1 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 31/152 (20%), Positives = 58/152 (38%), Gaps = 24/152 (15%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 IN+G + HV GK+T+ ++ +LG + E Sbjct: 4 INLGILAHVDAGKTTLTESLLYTS----------GAIAELGSVD------------EGTT 41 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 + + + V+ +D PGH ++ + +V+D A+LL++ Sbjct: 42 RTDTMNLERQRGITIQTAVTSFQWEDVKVNIIDTPGHMDFLAEVYRSLSVLDGAVLLVSA 101 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVD 252 + Q QT A++IMK+ + NK+D Sbjct: 102 KDGI-QAQTRILFHALQIMKIPTIF-FINKID 131 >3WNB-A nrPDB Length = 370 Score = 79.9 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 67/364 (18%), Positives = 131/364 (35%), Gaps = 58/364 (15%) Query: 156 PEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAAL 215 E S ++ K R++ FVD + + ++++ + D A+ Sbjct: 29 TEKSGRTSLAANLGKKGTSSDITMYNNDKEGRNMVFVDAHSYPKTLKSLITALNISDIAV 88 Query: 216 LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIA 275 L I + T E + A++++ KH II + D + E + + GT+ Sbjct: 89 LCIPP-QGL-DAHTGECIIALDLLGFKHGIIALTRSDSTHMHAIDELKAKLKVITSGTVL 146 Query: 276 DGAPIVPI----SAQLKY-NIDAVN---EFIVKTIPVPPRDFMISP-RLIVIRSFDVNKP 326 + + SA+ + +D + + + I + P R+ + +F+V Sbjct: 147 QDWECISLNTNKSAKNPFEGVDELKARINEVAEKIEAENAELNSLPARIFIDHAFNVTG- 205 Query: 327 GAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQND 386 KG V G + G+ K D+ +I P I S+ + D Sbjct: 206 -------KGCVVLGVVKQGISKDKDKTKIFPLDRDI-------------EIRSIQSHDVD 245 Query: 387 LKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYT-DIEINYFLLRRLLGVKT 445 + A G +G+ K + D G ++ K + YT + ++ F Sbjct: 246 IDSAPAGTRVGMRLK---NVQAKDIERGFIISDKEIVTTDYTLECTVSKF---------- 292 Query: 446 DGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMARLQLTSPACT-----EINEKIA 500 +K+EP VL + +G + RV + D ++ P T N+K+A Sbjct: 293 -------TKKIEPASVLHLFVGLQSEPVRVEKILVDGNEVEEAKPGSTCVLELSGNKKLA 345 Query: 501 LSRR 504 S++ Sbjct: 346 YSKQ 349 >4V6W-Az nrPDB Length = 844 Score = 76.4 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 42/207 (20%), Positives = 73/207 (35%), Gaps = 42/207 (20%) Query: 94 IINRQATI-NIGTIGHVAHGKSTVVRAISGVQ-------------TVRFKDELERNITIK 139 +++++ I N+ I HV HGKST+ ++ T KDE ER ITIK Sbjct: 12 LMDKKRNIRNMSVIAHVDHGKSTLTDSLVSKAGIIAGAKAGETRFTDTRKDEQERCITIK 71 Query: 140 LGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDI 199 + F+ +++ P + ++ +D PGH Sbjct: 72 STAIS-----------------MYFEVEEKDLVFITHPDQREKECKGFLINLIDSPGHVD 114 Query: 200 LMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDL------ 253 S + + V D AL+++ QT L ++K ++ NK+D Sbjct: 115 FSSEVTAALRVTDGALVVVDCVSGVCV-QTETVLRQAIAERIKPIL-FMNKMDRALLELQ 172 Query: 254 MREESA---LEHQKSILKFIRGTIADG 277 + E + + I T D Sbjct: 173 LDAEELYQTFQRIVENVNVIIATYNDD 199 >5I4Q-C nrPDB Length = 217 Score = 74.1 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 34/162 (20%), Positives = 61/162 (37%), Gaps = 23/162 (14%) Query: 283 ISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSI 342 A+ + I + F+ IP P R L + F ++ +G V G + Sbjct: 4 GDAEWEAKILELAGFLDSYIPEPERAIDKPFLLPIEDVFSISG--------RGTVVTGRV 55 Query: 343 LNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKV 402 G+ K+G+E+EI V + K C + + L G +GV + Sbjct: 56 ERGIIKVGEEVEI----VGIKETQKSTC-------TGVEMFRKLLDEGRAGENVGVLLR- 103 Query: 403 DPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLRRLLGVK 444 + R + GQV+ G + +T E ++L + G + Sbjct: 104 --GIKREEIERGQVLAKPGTIKP-HTKFESEVYILSKDEGGR 142 >5H7K-A nrPDB Length = 397 Score = 73.4 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 60/172 (34%), Gaps = 26/172 (15%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG H+ HGK+T+ + + ++ + + + + Sbjct: 26 NIGIAAHIDHGKTTLSDNLLAGAGMISEELAGKQLVLDFD--------------EQEQAR 71 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + +S G ++ +D PGH + +D ++++ Sbjct: 72 GITINAANVSMVHNYEGKDYL------INLIDTPGHVDFGGDVTRAMRAIDGVIIVVDAV 125 Query: 222 ESCPQPQTSEHLAAIEIMKLKHV--IILQNKVDLMREESALEHQKSILKFIR 271 E PQT + ++V ++ NKVD + E L Q+ + +F + Sbjct: 126 EGV-MPQTE---TVVRQALREYVKPVLFINKVDRLIRELKLTPQQMMERFSK 173 Score = 32.1 bits (71), Expect = 0.56, Method: Composition-based stats. Identities = 25/109 (22%), Positives = 41/109 (37%), Gaps = 21/109 (19%) Query: 330 IEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKF 389 I+ G VA G + +G K G E+ ++ K +IQ I+ + Sbjct: 304 IDKHAGEVATGRVWSGTVKSGQEVY----LINTKRKARIQQVGIYMGPERINM------E 353 Query: 390 AVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLR 438 AVP G I T + D + G+ V + P E +++L Sbjct: 354 AVPAGNIVAVTGL------RDAMAGETVAEEQIEP-----FEALHYVLE 391 >5H7J-A nrPDB Length = 743 Score = 73.0 bits (177), Expect = 3e-13, Method: Composition-based stats. Identities = 28/172 (16%), Positives = 60/172 (34%), Gaps = 26/172 (15%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG H+ HGK+T+ + + ++ + + + + Sbjct: 26 NIGIAAHIDHGKTTLSDNLLAGAGMISEELAGKQLVLDFD--------------EQEQAR 71 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + +S G ++ +D PGH + +D ++++ Sbjct: 72 GITINAANVSMVHNYEGKDYL------INLIDTPGHVDFGGDVTRAMRAIDGVIIVVDAV 125 Query: 222 ESCPQPQTSEHLAAIEIMKLKHV--IILQNKVDLMREESALEHQKSILKFIR 271 E PQT + ++V ++ NKVD + E L Q+ + +F + Sbjct: 126 EGV-MPQTE---TVVRQALREYVKPVLFINKVDRLIRELKLTPQQMMERFSK 173 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 36/180 (20%), Positives = 63/180 (35%), Gaps = 34/180 (18%) Query: 330 IEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKF 389 I+ G VA G + +G K G E+ ++ K +IQ I+ + Sbjct: 304 IDKHAGEVATGRVWSGTVKSGQEVY----LINTKRKARIQQVGIYMGPERINM------E 353 Query: 390 AVPGGLIGVGTKVDPTLCRADRLVGQVVG----------AKGHLPNIYTDIEIN-YFLLR 438 AVP G I T + D + G+ V P + IE L Sbjct: 354 AVPAGNIVAVTGL------RDAMAGETVAEEQIEPFEALHYVSEPVVTVAIEAKNVKDLP 407 Query: 439 RLLGVKTDGQKQ-----AKVRKLEPNEVLMVNIGSTATGARVVAVKADM-ARLQLTSPAC 492 RL+ K+ K+ + E + L+ +G ++ +K D ++++ P Sbjct: 408 RLIEALRQLAKEDPTLHVKIDE-ETGQHLLSGMGELHLEVKLYKLKKDWGIDIEVSEPIV 466 >2P8Y-T nrPDB Length = 842 Score = 72.2 bits (175), Expect = 5e-13, Method: Composition-based stats. Identities = 42/201 (20%), Positives = 70/201 (34%), Gaps = 49/201 (24%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQ-------------TVRFKDELERNITIKLGYANAKIY 148 N+ I HV HGKST+ ++ T KDE ER ITIK +Y Sbjct: 21 NMSVIAHVDHGKSTLTDSLVQRAGIISAAKAGEARFTDTRKDEQERGITIKS--TAISLY 78 Query: 149 KCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGA 208 + ++ + ++ +D PGH S + + Sbjct: 79 SEMSDEDVKEIKQKTDGNSFL-------------------INLIDSPGHVDFSSEVTAAL 119 Query: 209 AVMDAALLLIAGNES-CPQPQTSEHLAAIEIMKLKHV-IILQNKVDL------MREESAL 260 V D AL+++ E C Q +T + + + +++ NKVD + +E Sbjct: 120 RVTDGALVVVDTIEGVCVQTET----VLRQALGERIKPVVVINKVDRALLELQVSKEDLY 175 Query: 261 E---HQKSILKFIRGTIADGA 278 + + I T AD Sbjct: 176 QTFARTVESVNVIVSTYADEV 196 >5VH6-A nrPDB Length = 409 Score = 70.3 bits (170), Expect = 2e-12, Method: Composition-based stats. Identities = 48/356 (13%), Positives = 105/356 (29%), Gaps = 66/356 (18%) Query: 88 NPLSAEIINRQATINIGTIGHVAHGKSTVV-RAISGVQTVRFKDELERNITIKLGYANAK 146 N ++ E + NIG + H+ GK+T R + + E + Sbjct: 2 NAMAREFSLEKTR-NIGIMAHIDAGKTTTTERILFYTGRIHKIGETHEGAS--------- 51 Query: 147 IYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLS 206 Q + + + + + V+ +D PGH + Sbjct: 52 ----QMDWMEQEQERGITITSAATTAQWKGY----------RVNIIDTPGHVDFTVEVER 97 Query: 207 GAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSI 266 V+D A+ ++ +PQT + + + NK+D + + Sbjct: 98 SLRVLDGAVAVLDAQSGV-EPQTETVWRQATTYGVPRI-VFVNKMDKIGADFLYS----- 150 Query: 267 LKFIRGTIADGAPIVPISAQLKYNIDAVNEFIV----------------KTIPVPPRDFM 310 + +R + A + + + N + + + + K IP ++ Sbjct: 151 VGTLRDRLQANAHAIQLPIGAEDNFEGIIDLVENVAYFYEDDLGTRSDAKEIPEEYKEQA 210 Query: 311 ISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGD-EIEIRPGIVTKDDKGK-- 367 R +I + + L+G L + G +E P +V K K Sbjct: 211 EELRNSLIEAVCELDEELMDKYLEGEEITIDELKAGIRKGTLNVEFYPVLVGSAFKNKGV 270 Query: 368 -------IQCKPIFSNIVSLFAEQNDLKF--------AVPGGLIGVGTKVDPTLCR 408 + P +++ ++ + D P + DP + + Sbjct: 271 QLVLDAVLDYLPAPTDVAAIKGTRPDTNEEIERHSSDEEPFSALAFKVMTDPYVGK 326 >5TY0-A nrPDB Length = 422 Score = 69.1 bits (167), Expect = 4e-12, Method: Composition-based stats. Identities = 35/222 (15%), Positives = 75/222 (33%), Gaps = 26/222 (11%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG HV GK+T + ++ K+G + + Sbjct: 13 NIGIAAHVDAGKTTTTERVLYYT----------GMSHKIGEVHDGAATMDWMVQEQERG- 61 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + C G +++ R ++ +D PGH M + V+D A+++ Sbjct: 62 ---ITITSAATTCYWSGMDKQFESHR-INIIDTPGHVDFMIEVERSLRVLDGAVVVFDSV 117 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIV 281 +PQ+ + + + NK+D M + L I + + T Sbjct: 118 AGV-EPQSETVWRQANKYGVPRI-VFVNKMDRMG-ANFLRVVSQIKQRLGST-------- 166 Query: 282 PISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDV 323 P+ QL + + ++ I + + + + + D+ Sbjct: 167 PVVLQLPIGAEEEFKGVIDLIKMKAIHWDEENKGMTFKYVDI 208 Score = 37.1 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 18/118 (15%), Positives = 33/118 (27%), Gaps = 20/118 (16%) Query: 256 EESALEHQKSILKFIRGTIADG----------APIVPISAQLKYNIDAVNEFIVKTIPVP 305 E +E +F I P+ SA + AV + +++ +P P Sbjct: 231 SEELMEKYLEGEEFTEAEIKKALRHLTITNKVVPVFCGSAFKNKGVQAVLDGVIEYLPSP 290 Query: 306 PRDFMIS----------PRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEI 353 I + F + G + +G+ K GD + Sbjct: 291 TDIPDIQGVDEHGDVIHRKTSYDEPFSALAFKIATDPFVGTLTYFRAYSGILKSGDTV 348 >4FN5-A nrPDB Length = 709 Score = 68.0 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 61/437 (13%), Positives = 138/437 (31%), Gaps = 59/437 (13%) Query: 91 SAEIINRQA---TINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKI 147 + + NIG HV GK+T + + KLG + Sbjct: 1 GSHMARTTPINRYRNIGICAHVDAGKTTTTERV----------LFYTGVNHKLGEVHDGA 50 Query: 148 YKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 + + + G G+Y R V+ +D PGH + Sbjct: 51 ATTDWMVQEQERG----ITITSAAVTTFWKGSRGQYDNYR-VNVIDTPGHVDFTIEVERS 105 Query: 208 AAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSIL 267 V+D A+++ G +PQ+ + + + NK+D + + L + I Sbjct: 106 LRVLDGAVVVFCGTSGV-EPQSETVWRQANKYGVPRI-VYVNKMDR-QGANFLRVVEQIK 162 Query: 268 KFI-------------RGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPR 314 K + ++ + A + D + + IP +D R Sbjct: 163 KRLGHTPVPVQLAIGAEENFVGQVDLIKMKAIYWNDDDKGMTYREEEIPAELKDLAEEWR 222 Query: 315 -LIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGK------ 367 +V + + N+ +G ++ I G+ EI P + K K Sbjct: 223 SSMVEAAAEANEELMNKYLEEGELSEAEIKEGLRLRTLACEIVPAVCGSSFKNKGVPLVL 282 Query: 368 ---IQCKPIFSNIVSLFA---------EQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQ 415 I P + I ++ ++ P + DP + + Sbjct: 283 DAVIDYLPAPTEIPAIKGVSPDDETVEDERHADDNEPFSSLAFKIATDPFV--GTLTFAR 340 Query: 416 V-VGAKGHLPNIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEV-LMVNIGSTATGA 473 V G ++ ++ + R++ + + +++ K ++ ++ ++ + TG Sbjct: 341 VYSGVLSSGDSVLNSVKGKKERVGRMVQMHANQREEIK--EVRAGDIAALIGMKDVTTGD 398 Query: 474 RVVAVKADMARLQLTSP 490 + +++ + ++ P Sbjct: 399 TLCSIEKPIILERMDFP 415 >6N0I-A nrPDB Length = 706 Score = 67.2 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 53/337 (15%), Positives = 99/337 (29%), Gaps = 49/337 (14%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG + HV GK+T I + K+G + + Sbjct: 15 NIGIVAHVDAGKTTTTERI----------LFYTGVNHKMGEVHDGAATMDWMAQEQERGI 64 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + +Y + +D PGH + V+D A+++ +G Sbjct: 65 TITSAATTAFWQGSTKQFAHKY----RFNIIDTPGHVDFTIEVERSLRVLDGAVVVFSGA 120 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFI----------- 270 + +PQ+ + + NK+D + L K I + + Sbjct: 121 DGV-EPQSETVWRQANKYHVPRL-AYINKMDR-QGADFLRVVKQIDQRLGHHPVPIQLAI 177 Query: 271 --RGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGA 328 +V + A + D + + IP + R +I + Sbjct: 178 GSEENFMGQIDLVKMKAIYWNDADQGTSYREEEIPAELKALADEWRAHMIEAAAEANDEL 237 Query: 329 EIEDLKG-GVAGGSILNGVFKLGDEIEIRPGIVTKDDKGK---------IQCKPIFSNIV 378 ++ L G ++ I G+ + EI P I+ K K I P S I Sbjct: 238 TMKFLDGEELSIEEIKAGLRQRTIANEIVPTILGSSFKNKGVPLMLDAVIDYLPAPSEIP 297 Query: 379 SLFAEQNDLKFAV---------PGGLIGVGTKVDPTL 406 ++ D + P + DP + Sbjct: 298 AIRGTDPDDEEKHLERHADDKEPFSALAFKIATDPFV 334 >3ZZ0-A nrPDB Length = 693 Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 25/153 (16%), Positives = 47/153 (30%), Gaps = 24/153 (15%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG I H+ GK+T I + T + + + Q+ Sbjct: 12 NIGIIAHIDAGKTTTTERILYY----TGRIHKIGETHEGASQMDWMEQEQDRGITITSAA 67 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + V+ +D PGH + V+D A+ ++ Sbjct: 68 TTAAWEGH------------------RVNIIDTPGHVDFTVEVERSLRVLDGAVTVLDAQ 109 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM 254 +PQT + + + NK+D + Sbjct: 110 SGV-EPQTETVWRQATTYGVPRI-VFVNKMDKL 140 >6MTD-v nrPDB Length = 839 Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 40/197 (20%), Positives = 72/197 (36%), Gaps = 44/197 (22%) Query: 94 IINRQATI-NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYAN--AKIYKC 150 I++++A I N+ I HV HGKST+ ++ + + R ITIK + ++ + Sbjct: 11 IMDKKANIRNMSVIAHVDHGKSTLTDSLVCKAGI-----IARCITIKSTAISLFYELSEN 65 Query: 151 QEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV 210 + F ++ +D PGH S + + V Sbjct: 66 DLNFIKQSKDGAGFL-----------------------INLIDSPGHVDFSSEVTAALRV 102 Query: 211 MDAALLLIAGNES-CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREE---------SAL 260 D AL+++ C Q +T A E +K +++ NK+D E Sbjct: 103 TDGALVVVDCVSGVCVQTETVLRQAIAERIKP---VLMMNKMDRALLELQLEPEELYQTF 159 Query: 261 EHQKSILKFIRGTIADG 277 + + I T +G Sbjct: 160 QRIVENVNVIISTYGEG 176 Score = 32.9 bits (73), Expect = 0.37, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 41/126 (32%), Gaps = 18/126 (14%) Query: 291 IDAVNEFIVKTIPVPPRD-----------FMISPRLIVIRSFDVNKPGA-------EIED 332 DA+ + I +P P + I+S D P D Sbjct: 328 GDALLQMITIHLPSPVTAQKYRCELLYEGPPDDEAAMGIKSCDPKGPLMMYISKMVPTSD 387 Query: 333 LKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVP 392 A G + +G+ G ++ I T K + KPI I+ + ++ Sbjct: 388 KGRFYAFGRVFSGLVSTGLKVRIMGPNYTPGKKEDLYLKPIQRTILMMGRYVEPIEDVPC 447 Query: 393 GGLIGV 398 G ++G+ Sbjct: 448 GNIVGL 453 >6BK7-A nrPDB Length = 407 Score = 65.3 bits (157), Expect = 7e-11, Method: Composition-based stats. Identities = 30/194 (15%), Positives = 59/194 (30%), Gaps = 27/194 (13%) Query: 88 NPLSAEIINRQATINIGTIGHVAHGKSTVV-RAISGVQTVRFKDELERNITIKLGYANAK 146 N ++ E + NIG + HV GK+T R + + E + Sbjct: 2 NAMAREFSLEKTR-NIGIMAHVDAGKTTTTERILYYTGKIHKIGETHEGAS--------- 51 Query: 147 IYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLS 206 Q + + + + + V+ +D PGH + Sbjct: 52 ----QMDWMEQEQERGITITSAATTAQWKGY----------RVNIIDTPGHVDFTIEVQR 97 Query: 207 GAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSI 266 V+D A+ ++ +PQT K+ + + NK+D + + + Sbjct: 98 SLRVLDGAVTVLDSQSGV-EPQTETVWRQATEYKVPRI-VFCNKMDKIGADFFYSVESLH 155 Query: 267 LKFIRGTIADGAPI 280 + PI Sbjct: 156 DRLQANAHPIQIPI 169 >6ID0-C nrPDB Length = 972 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 46/241 (19%), Positives = 73/241 (30%), Gaps = 49/241 (20%) Query: 19 PVGEPDIVEETEVVAQE--TQE-TQDADKPKKKVAFTGLEEDGETEEEKRKREFEEGGGL 75 P E E E + QE TQ T+ KP K FT +E+ L Sbjct: 67 PTAEEVYGPEVETIVQEEDTQPLTEPIIKPVKTKKFTLMEQT-----------------L 109 Query: 76 PEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERN 135 P DF ++E+I N+ GH+ HGK+ V + + +R Sbjct: 110 PVTVYEMDFLADLMDNSELIR-----NVTLCGHLHHGKTCFVDCLIE---QTHPEIRKR- 160 Query: 136 ITIKLGYANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCP 195 + C + + I P + +D P Sbjct: 161 --------------YDQDLCYTDILFTEQERGVGIKSTPVTVVLPDTKGKSYLFNIMDTP 206 Query: 196 GHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTS--EHLAAIEIMKLKHVIILQNKVDL 253 GH + +G + D +L I E +H + V + NK+D Sbjct: 207 GHVNFSDEVTAGLRISDGVVLFIDAAEGVMLNTERLIKHAVQERLA----VTVCINKIDR 262 Query: 254 M 254 + Sbjct: 263 L 263 >1WDT-A nrPDB Length = 665 Score = 62.6 bits (150), Expect = 5e-10, Method: Composition-based stats. Identities = 44/261 (16%), Positives = 79/261 (30%), Gaps = 48/261 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +GH GK+T+ A+ + + R E Sbjct: 12 VALVGHAGSGKTTLTEALLY----KTGAKERRG------------------RVEEGTTTT 49 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + + ++ R G V +D PG+ + + DAAL+ ++ Sbjct: 50 DYTPEAKLHRTTVRTGVAPLLFRGHRVFLLDAPGYGDFVGEIRGALEAADAALVAVSAEA 109 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 T E + L +++ K+D + AL L+ +R T+ PI+P Sbjct: 110 GVQVG-TERAWTVAERLGLPRMVV-VTKLDKGGDYYAL------LEDLRSTLG---PILP 158 Query: 283 ISAQLKYNID---------------AVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPG 327 I L E +P R+ + R V+ + G Sbjct: 159 IDLPLYEGGKWVGLIDVFHGKAYRYENGEEREAEVPPEERERVQRFRQEVLEAIVETDEG 218 Query: 328 AEIEDLKGGVAGGSILNGVFK 348 + L+G G L F Sbjct: 219 LLEKYLEGEEVTGEALEKAFH 239 >3VQT-A nrPDB Length = 548 Score = 61.4 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 31/172 (18%), Positives = 59/172 (34%), Gaps = 25/172 (14%) Query: 87 LNPLSAEIINRQATI-----NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLG 141 L P + + +R I H GK+T+ + L I++ Sbjct: 13 LVPRGSHMSSRLEREAARRRTFAIISHPDAGKTTLTEKL-----------LLFGGAIQMA 61 Query: 142 YANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILM 201 + + T + + + ++ IS P R R V+ +D PGH Sbjct: 62 GSVKARKAARHATSD----WMAMERERGISVTTSVMQFPYR---DRVVNLLDTPGHQDFS 114 Query: 202 STMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDL 253 +D+AL++I + + QT + + + V+ NK+D Sbjct: 115 EDTYRVLTAVDSALVVIDAAKGV-EAQTRKLMDVCRMRATP-VMTFVNKMDR 164 >4V89-AW nrPDB Length = 534 Score = 61.4 bits (147), Expect = 9e-10, Method: Composition-based stats. Identities = 26/187 (13%), Positives = 53/187 (28%), Gaps = 29/187 (15%) Query: 87 LNPLSAEIINRQATINIGTIGHVAHGKSTVVRA--ISGVQTVRFKDELERNITIKLGYAN 144 L+P E+ R+ I H GK+T+ + G R Sbjct: 3 LSPYLQEVAKRRT---FAIISHPDAGKTTITEKVLLFGQAIQTAGTVKGRGSNQH----- 54 Query: 145 AKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTM 204 + + + V+ +D PGH+ Sbjct: 55 -----AKSDWMEMEKQRGISITTSVMQFPYHDCL----------VNLLDTPGHEDFSEDT 99 Query: 205 LSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKV--DLMREESALEH 262 +D L++I + +T + + + ++ NK+ D+ L+ Sbjct: 100 YRTLTAVDCCLMVIDAAKGVED-RTRKLMEVTRLRDTP-ILTFMNKLDRDIRDPMELLDE 157 Query: 263 QKSILKF 269 ++ LK Sbjct: 158 VENELKI 164 >3TR5-A nrPDB Length = 528 Score = 61.4 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 27/169 (15%), Positives = 54/169 (31%), Gaps = 22/169 (13%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 I H GK+T+ + + G A + Sbjct: 16 FAIISHPDAGKTTLTEKL-----------------LLFGGAIQLAGTIKSRKAARHATSD 58 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + +K+ YK ++ +D PGH +D+AL++I + Sbjct: 59 WMELEKQRGISVTTSVMQFPYKDYL-INLLDTPGHADFTEDTYRTLTAVDSALMVIDAAK 117 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREE--SALEHQKSILKF 269 +P+T + + + ++ NK+D L+ +SIL+ Sbjct: 118 GV-EPRTIKLMEVCRLRHTP-IMTFINKMDRDTRPSIELLDEIESILRI 164 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 35/208 (16%), Positives = 74/208 (35%), Gaps = 27/208 (12%) Query: 274 IADGAPIVPISAQLKYNIDAVNEFIVKTIPVPP-RDFMISPRLIVIRSFD---VNKPGAE 329 + PI SA + + + + VK P P R+ F Sbjct: 247 KGELTPIFFGSAINNFGVGELLDAFVKEAPPPQGRETNSRLVKPEEEKFSGFVFKIQANM 306 Query: 330 IEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQND-LK 388 + +A I +G ++ G K +++ + +N ++ A + + + Sbjct: 307 DPGHRDRIAFLRIASGQYQKG----------MKAYHVRLKKEIQINNALTFMAGKRENAE 356 Query: 389 FAVPGGLIGV----GTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEIN-----YFLLRR 439 A PG +IG+ ++ T + +R G ++ + + LL+ Sbjct: 357 EAWPGDIIGLHNHGTIQIGDTFTQGERFK--FTGIPNFASELFRLVRLKDPLKQKALLKG 414 Query: 440 LLGVKTDGQKQAKVRKLEPNEVLMVNIG 467 L + +G Q R L+ NE+++ +G Sbjct: 415 LTQLSEEGATQL-FRPLDSNELILGAVG 441 >4WQY-BZ nrPDB Length = 758 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 67/437 (15%), Positives = 128/437 (29%), Gaps = 74/437 (16%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG H+ GK+T I + E Sbjct: 81 NIGIAAHIDAGKTTTTERILY----------------------YTGRIHKIGEVHEGAAT 118 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 F + + ++ +D PGH + V+D A+++ + Sbjct: 119 MDFMEQERERGITITAAVTTCFWKDHRINIIDTPGHVDFTIEVERSMRVLDGAIVVFDSS 178 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKS---------ILKFIRG 272 + +PQ+ E K+ + NK+D + L + +++ G Sbjct: 179 QGV-EPQSETVWRQAEKYKVPRI-AFANKMDKTGADLWLVIRTMQERLGARPVVMQLPIG 236 Query: 273 TIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPR-----DFMISPRLIVIRSFDVNK-- 325 + I+ + Y ++ IP+P + V FD N Sbjct: 237 REDTFSGIIDVLRMKAYTYGNDLGTDIREIPIPEEYLDQAREYHEKLVEVAADFDENIML 296 Query: 326 PGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGK------------------ 367 E E+ +I G +++I P + K K Sbjct: 297 KYLEGEEPTEEELVAAIRKGTI----DLKITPVFLGSALKNKGVQLLLDAVVDYLPSPLD 352 Query: 368 ---IQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLP 424 I+ +V + + N P + DP + R + G Sbjct: 353 IPPIKGTTPEGEVVEIHPDPN-----GPLAALAFKIMADPYVGRLTFIR-VYSGTLTSGS 406 Query: 425 NIYTDIEINYFLLRRLLGVKTDGQKQAKVRKLEPNEVLMVNIGSTATGARVVAVKADMAR 484 +Y + + RLL + + +++ V +L+ ++ V +G T V D R Sbjct: 407 YVYNTTKGRKERVARLLRMHANHREE--VEELKAGDLGAV-VGLKETITGDTLVGEDAPR 463 Query: 485 LQLTSPACTEINEKIAL 501 + L S E +A+ Sbjct: 464 VILESIEVPEPVIDVAI 480 >6B8D-A nrPDB Length = 408 Score = 60.3 bits (144), Expect = 2e-09, Method: Composition-based stats. Identities = 24/153 (15%), Positives = 45/153 (29%), Gaps = 17/153 (11%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG H+ GK+T I ++ K+G + + Sbjct: 15 NIGISAHIDAGKTTTTERI----------LFYTGVSHKIGEVHDGAATMDWMEQEQERGI 64 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + P ++ +D PGH + V+D A+++ Sbjct: 65 TITSAATTAFWSGMSQQFPQH-----RINVIDTPGHVDFTVEVERSMRVLDGAVMVY-CA 118 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM 254 QPQ+ ++ + NK+D Sbjct: 119 VGGVQPQSETVWRQANKYEVPRI-AFVNKMDRT 150 Score = 32.1 bits (71), Expect = 0.55, Method: Composition-based stats. Identities = 26/174 (14%), Positives = 50/174 (28%), Gaps = 30/174 (17%) Query: 263 QKSILKFIRGTIADGAPIVP--ISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLI---- 316 ++ I +R + I+ SA + A+ + +V+ +P P I Sbjct: 248 EEEIKSALRQRVLANEIILVTCGSAFKNKGVQAMLDAVVEYLPAPTDIPAIKGINPDETE 307 Query: 317 ------VIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQC 370 F + G + + +GV GD + Q Sbjct: 308 GERHASDEEPFSSLAFKIATDPFVGNLTFFRVYSGVINSGDTV----------LNSVRQK 357 Query: 371 KPIFSNIVSLFAEQ-NDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHL 423 + F IV + A + ++K G + + D G + A Sbjct: 358 RERFGRIVQMHANKREEIKEVRAGD-------IAAAIGLKDVTTGDTLCAIDAP 404 >5G06-P nrPDB Length = 747 Score = 59.9 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 72/434 (16%), Positives = 136/434 (31%), Gaps = 76/434 (17%) Query: 92 AEIINRQA-TINIGTIGHVAHGKSTVVRAI----SGVQTVRFKDELERNITIKLGYANAK 146 I + +G GKST++ + + + ++ +++ + +N+ Sbjct: 258 HSFIATHPLNLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSF 317 Query: 147 IYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILM-STML 205 + + FK ++ P ++ +D PG L Sbjct: 318 KVILDNTKTERENGFSMFKKVIQVENDLLPPSST--------LTLIDTPGSIKYFNKETL 369 Query: 206 SGAAVMD--AALLLIAGNESC-------PQPQTSEHLAAIE-----IMKLKHVIILQNKV 251 + D +L+I N P Q E L I KH+IIL NK Sbjct: 370 NSILTFDPEVYVLVIDCNYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKA 429 Query: 252 DLMR-EESALEHQKSILKFIRGTIAD----GAPIVPISAQLKYNIDAVNEFIVKTIPVPP 306 DL+ ++ LE +S L ++ +P S L N++ Sbjct: 430 DLISWDKHRLEMIQSELNYVLKENFQWTDAEFQFIPCSGLLGSNLNKTENITKSKYKSEF 489 Query: 307 RDFMISPR----------LIVIRSFDVNKPGAEIED-LKGGVAGGS-------------- 341 P L ++ ++NK +E+ G + S Sbjct: 490 DSINYVPEWYEGPTFFSQLYLLVEHNMNKIETTLEEPFVGTILQSSVLQPIAEINYVSLK 549 Query: 342 --ILNGVFKLGDEIEIRP--------GIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAV 391 I +G + G IEI GIV++ K + N +S+ + L+ Sbjct: 550 VLINSGYIQSGQTIEIHTQYEDFHYYGIVSRMKNSKQILETNTKNNISVGLNPDILEV-- 607 Query: 392 PGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLR-RLLGVKTDGQKQ 450 L+ + D T + G ++ + ++ LL RL+ K Q Sbjct: 608 ---LVKIHNTEDFTKKQFHIRKGDIIIHSRKTNTLSPNLPNTLKLLALRLI--KLSIQTH 662 Query: 451 AKVRKLEPNEVLMV 464 A ++ L++ Sbjct: 663 ALSDPVDLGSELLL 676 >4ZKD-A nrPDB Length = 499 Score = 59.9 bits (143), Expect = 2e-09, Method: Composition-based stats. Identities = 72/434 (16%), Positives = 136/434 (31%), Gaps = 76/434 (17%) Query: 92 AEIINRQA-TINIGTIGHVAHGKSTVVRAI----SGVQTVRFKDELERNITIKLGYANAK 146 I + +G GKST++ + + + ++ +++ + +N+ Sbjct: 10 HSFIATHPLNLTCLFLGDTNAGKSTLLGHLLYDLNEISMSSMRELQKKSSNLDPSSSNSF 69 Query: 147 IYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILM-STML 205 + + FK ++ P ++ +D PG L Sbjct: 70 KVILDNTKTERENGFSMFKKVIQVENDLLPPSST--------LTLIDTPGSIKYFNKETL 121 Query: 206 SGAAVMD--AALLLIAGNESC-------PQPQTSEHLAAIE-----IMKLKHVIILQNKV 251 + D +L+I N P Q E L I KH+IIL NK Sbjct: 122 NSILTFDPEVYVLVIDCNYDSWEKSLDGPNNQIYEILKVISYLNKNSACKKHLIILLNKA 181 Query: 252 DLMR-EESALEHQKSILKFIRGTIAD----GAPIVPISAQLKYNIDAVNEFIVKTIPVPP 306 DL+ ++ LE +S L ++ +P S L N++ Sbjct: 182 DLISWDKHRLEMIQSELNYVLKENFQWTDAEFQFIPCSGLLGSNLNKTENITKSKYKSEF 241 Query: 307 RDFMISPR----------LIVIRSFDVNKPGAEIED-LKGGVAGGS-------------- 341 P L ++ ++NK +E+ G + S Sbjct: 242 DSINYVPEWYEGPTFFSQLYLLVEHNMNKIETTLEEPFVGTILQSSVLQPIAEINYVSLK 301 Query: 342 --ILNGVFKLGDEIEIRP--------GIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAV 391 I +G + G IEI GIV++ K + N +S+ + L+ Sbjct: 302 VLINSGYIQSGQTIEIHTQYEDFHYYGIVSRMKNSKQILETNTKNNISVGLNPDILEV-- 359 Query: 392 PGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLR-RLLGVKTDGQKQ 450 L+ + D T + G ++ + ++ LL RL+ K Q Sbjct: 360 ---LVKIHNTEDFTKKQFHIRKGDIIIHSRKTNTLSPNLPNTLKLLALRLI--KLSIQTH 414 Query: 451 AKVRKLEPNEVLMV 464 A ++ L++ Sbjct: 415 ALSDPVDLGSELLL 428 >5TV2-A nrPDB Length = 405 Score = 59.9 bits (143), Expect = 3e-09, Method: Composition-based stats. Identities = 25/152 (16%), Positives = 48/152 (31%), Gaps = 17/152 (11%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG HV GK+T I ++ K+G + + Sbjct: 12 NIGICAHVDAGKTTTTERI----------LFYTGLSHKIGEVHDGAATMDWMEQEQERGI 61 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + V+ +D PGH + V+D A+++ G+ Sbjct: 62 TITSAATTTFWRGMEAQFQDH-----RVNIIDTPGHVDFTIEVERSLRVLDGAVVVFCGS 116 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDL 253 +PQ+ + + + + NK+D Sbjct: 117 SGV-EPQSETVWRQADKYHVPRM-VFVNKMDR 146 Score = 36.0 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 35/171 (20%), Positives = 59/171 (34%), Gaps = 28/171 (16%) Query: 261 EHQKSILKFIRGTIADGAPIVP---ISAQLKYNIDAVNEFIVKTIPVPPRDF----MISP 313 E ++ +K IV SA + AV + +++ +P P + Sbjct: 242 ELTEAEIKQALRARTLNNEIVLATCGSAFKNKGVQAVLDAVIEYLPSPIDVPAIKGIDEN 301 Query: 314 RLIVIRSFDVNKPGAEI------EDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGK 367 V R D N+P + + + G + + +GV GD + Sbjct: 302 DNEVERHADDNEPFSALAFKIATDPFVGTLTFIRVYSGVVNTGDAV----------YNSV 351 Query: 368 IQCKPIFSNIVSLFAEQ-NDLKFAVPGG---LIGV-GTKVDPTLCRADRLV 413 Q K F IV + A + ++K G IG+ TLC +D V Sbjct: 352 KQKKERFGRIVQMHANKREEIKEVRAGDIAAAIGLKDVTTGDTLCNSDHKV 402 >4V7D-BZ nrPDB Length = 711 Score = 59.1 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 32/196 (16%), Positives = 62/196 (31%), Gaps = 19/196 (9%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG H+ GK+T I + K+G + + Sbjct: 11 NIGISAHIDAGKTTTTERI----------LFYTGVNHKIGEVHDGAATMDWMEQEQERG- 59 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + G +Y+ R ++ +D PGH + V+D A+++ Sbjct: 60 ---ITITSAATTAFWSGMAKQYEPHR-INIIDTPGHVDFTIEVERSMRVLDGAVMVYCAV 115 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIV 281 QPQ+ K+ + NK+D M + L+ I K G + Sbjct: 116 GGV-QPQSETVWRQANKYKVPRI-AFVNKMDRMG-ANFLKVVNQI-KTRLGANPVPLQLA 171 Query: 282 PISAQLKYNIDAVNEF 297 + + + + + Sbjct: 172 IGAEEHFTGVVDLVKM 187 Score = 36.4 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 26/206 (12%), Positives = 61/206 (29%), Gaps = 32/206 (15%) Query: 260 LEHQKSILKFIRGTIADGAPIVPI---SAQLKYNIDAVNEFIVKTIPVPP---------- 306 E ++ +K I+ + SA + A+ + ++ +P P Sbjct: 240 EELTEAEIKGALRQRVLNNEIILVTCGSAFKNKGVQAMLDAVIDYLPSPVDVPAINGILD 299 Query: 307 --RDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDD 364 +D F + G + + +GV GD + + ++ Sbjct: 300 DGKDTPAERHASDDEPFSALAFKIATDPFVGNLTFFRVYSGVVNSGDTV-LNSVKAARER 358 Query: 365 KGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLP 424 G+I + ++ ++K G + + D G + P Sbjct: 359 FGRI--------VQMHANKREEIKEVRAGD-------IAAAIGLKDVTTGDTLCDPDA-P 402 Query: 425 NIYTDIEINYFLLRRLLGVKTDGQKQ 450 I +E ++ + KT ++ Sbjct: 403 IILERMEFPEPVISIAVEPKTKADQE 428 >3JB9-B nrPDB Length = 984 Score = 58.0 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 24/154 (15%), Positives = 49/154 (31%), Gaps = 24/154 (15%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 GH+ HGKS ++ + K R++ + + + P Sbjct: 144 FIVAGHLHHGKSALLDLLVYYTHPDTKPPKRRSLRYTDTHYLERERVMSIKSTPLTLAVS 203 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 K +D PGH + + + A+ D +L++ E Sbjct: 204 DMKGKTFA------------------FQCIDTPGHVDFVDEVAAPMAISDGVVLVVDVIE 245 Query: 223 SCPQPQTS--EHLAAIEIMKLKHVIILQNKVDLM 254 T +H ++ ++++ NKVD + Sbjct: 246 GVMINTTRIIKHAILHDMP----IVLVLNKVDRL 275 >6NOT-A nrPDB Length = 707 Score = 56.8 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 50/166 (30%), Gaps = 25/166 (15%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 NIG H+ GK+T I + + G + + QE Sbjct: 20 NIGICAHIDAGKTTTTERILYYTGKSH----KIGEVHEGGATMDWMEQEQERGITITSAA 75 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 + + ++ ++ +D PGH + V+D A+ + G Sbjct: 76 TTCRWQDKV------------------INIIDTPGHVDFTIEVERSLRVLDGAVAVFDGV 117 Query: 222 ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSIL 267 +PQ+ + + + NK+D M + I Sbjct: 118 AGV-EPQSETVWRQADKYNVPRM-CFVNKMDRMG-ADFYRCVEMIK 160 Score = 35.2 bits (79), Expect = 0.063, Method: Composition-based stats. Identities = 26/204 (12%), Positives = 59/204 (28%), Gaps = 31/204 (15%) Query: 261 EHQKSILKFIRGTIADGAPIVPI---SAQLKYNIDAVNEFIVKTIPVPPR---------- 307 E + +K + A PI SA + + + IV +P P Sbjct: 243 EITEEQIKILIRKGTIEARFYPILCGSAFKNKGVQPLLDAIVDFLPSPIDIGIVKGIEVS 302 Query: 308 -DFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKG 366 + ++ F + G + I +G G + + Sbjct: 303 TSEEKDFPISIVEPFSALAFKIMNDPFVGSLTFIRIYSGKITSGATVI---------NTV 353 Query: 367 KIQCKPIFSNIVSLFAEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNI 426 K + + I ++ + D+K A G ++ + D G + + Sbjct: 354 KNKREKIGRMLLMHANNREDIKEASAGDIVALA-------GLKDTSTGDTLSDIDK-QVV 405 Query: 427 YTDIEINYFLLRRLLGVKTDGQKQ 450 +E ++ + K+ ++ Sbjct: 406 LERMEFPEPVIELAVEPKSTADQE 429 >5KH0-A nrPDB Length = 396 Score = 52.9 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 22/146 (15%), Positives = 48/146 (32%), Gaps = 21/146 (14%) Query: 174 CQRPGCPGRYKLVRHVSFVDCPGHDIL-------MSTMLSGAAVMDAALLLIAGNESCPQ 226 V ++ +D PG D + + D +L++ + Sbjct: 44 TDPVFKSMELSPVGPITLIDTPGLDDVGELGIKRIKKAKKSLYRADCGILIVDDIPGNFE 103 Query: 227 PQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQ 286 Q + + +++ + I NK+D + E+ + K PI+ +SA Sbjct: 104 EQI---IKLFKELEIPY-FIAINKIDTIDHENIEKEYKKY----------NVPILKVSAL 149 Query: 287 LKYNIDAVNEFIVKTIPVPPRDFMIS 312 K + + + I +P +S Sbjct: 150 KKIGFEKIGKTINSILPKDDEIPYLS 175 >3R9W-A nrPDB Length = 307 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 37/179 (20%), Positives = 63/179 (35%), Gaps = 21/179 (11%) Query: 188 HVSFVDCPG------HDILMSTMLSGAAV----MDAALLLIAGNESCPQPQTSEHLAAIE 237 + F+D PG D+L +M+ A D L +I E + I+ Sbjct: 59 QIIFLDTPGIYEPKKSDVLGHSMVEIAKQSLEEADVILFMIDATEGWRPRDEEIYQNFIK 118 Query: 238 IMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEF 297 + VI++ NK+D + ++ ++ I + IVPISA N+D + + Sbjct: 119 PLNKP-VIVVINKIDKIGPA---KNVLPLIDEIHKKHPELTEIVPISALKGANLDELVKT 174 Query: 298 IVKTIPV-----PPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAGGSILNGVFKLGD 351 I+K +P P P ++ K + I K GD Sbjct: 175 ILKYLPEGEPLFPEDMITDLPLRLLAAEIVREKAMMLTREEVPTSIAVKINE--IKPGD 231 >1U0L-A nrPDB Length = 301 Score = 48.3 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 17/105 (16%), Positives = 40/105 (38%), Gaps = 7/105 (6%) Query: 202 STMLSG--AAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESA 259 +L+ A +D +L++ + + +++ NK+DL E+ Sbjct: 74 KNLLTKPHVANVDQVILVVTVKMPETSTYIIDKFLVLAEKNELETVMVINKMDLYDEDDL 133 Query: 260 LEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPV 304 + ++ + + PIV SA+ I+ + E++ I Sbjct: 134 RK-----VRELEEIYSGLYPIVKTSAKTGMGIEELKEYLKGKIST 173 >2QTH-A nrPDB Length = 364 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 30/200 (15%), Positives = 67/200 (33%), Gaps = 37/200 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 IG +G+ GK+++ +++G +T K+ + P + Sbjct: 182 IGIVGYTNSGKTSLFNSLTG-------------LTQKVDTKLFTTMSPKRYAIPINNRKI 228 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN- 221 VD ++ LS A DA +L+I Sbjct: 229 MLVDTVGFIRGIPPQ-------------IVDA----FFVT--LSEAKYSDALILVIDSTF 269 Query: 222 -ESCPQPQTSEHLAAIEIMKL--KHVIILQNKVDLMREESALEHQKSILKFIRGTIADGA 278 E+ + + + K +++ NK+D + + + + K + + Sbjct: 270 SENLLIETLQSSFEILREIGVSGKPILVTLNKIDKINGD-LYKKLDLVEKLSKELYSPIF 328 Query: 279 PIVPISAQLKYNIDAVNEFI 298 ++PISA + N++ + + I Sbjct: 329 DVIPISALKRTNLELLRDKI 348 >1MKY-A nrPDB Length = 439 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 51/335 (15%), Positives = 107/335 (31%), Gaps = 52/335 (15%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +G GKST+ + V+ + E E +T P D Sbjct: 4 VLIVGRPNVGKSTLFNKL--VKKKKAIVEDEEGVTRD----------------PVQDTVE 45 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + ++ C P + + M+ D L ++ G Sbjct: 46 WYGKTFKLVDTCGVFDNPQDIISQKM---------KEVTLNMIR---EADLVLFVVDGKR 93 Query: 223 SCPQPQTSEHLAAIEIMKLKHV--IILQNKVDLMREESALEHQKSILKFIRGTIADGAPI 280 T E + + ++ V I++ NK E+ E ++ + + Sbjct: 94 GI----TKEDESLADFLRKSTVDTILVANKA-----ENLREFEREVKPELYSLGFGEP-- 142 Query: 281 VPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLI-VIRSFDVNKPGAEIEDLKGGVAG 339 +P+SA+ N+D + E I+K + D P + I+ V +P L + Sbjct: 143 IPVSAEHNINLDTMLETIIKKLEEKGLDLESKPEITDAIKVAIVGRPNVGKSTLFNAILN 202 Query: 340 G-----SILNGVFK--LGDEIEIR-PGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAV 391 S + G + + DE+ I V D G + + V ++ + Sbjct: 203 KERALVSPIPGTTRDPVDDEVFIDGRKYVFVDTAGLRRKSRVEPRTVEKYSNYRVVDSIE 262 Query: 392 PGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNI 426 ++ + + R D+ + ++ +G + Sbjct: 263 KADVVVIVLDATQGITRQDQRMAGLMERRGRASVV 297 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 26/145 (17%), Positives = 50/145 (34%), Gaps = 18/145 (12%) Query: 168 KEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMS------------TMLSGAAVMDAAL 215 I + P + R FVD G ++ D + Sbjct: 209 SPIPGTTRDPVDDEVFIDGRKYVFVDTAGLRRKSRVEPRTVEKYSNYRVVDSIEKADVVV 268 Query: 216 LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLM--REESALEHQKSILKFIRGT 273 +++ + + Q +E V++ NK DL+ RE+ E K + + Sbjct: 269 IVLDATQGITR-QDQRMAGLMERRGRASVVVF-NKWDLVVHREKRYDEFTKLFREKL--Y 324 Query: 274 IADGAPIVPISAQLKYNIDAVNEFI 298 D +P++ SA +NID + + + Sbjct: 325 FIDYSPLIFTSADKGWNIDRMIDAM 349 >3PR1-A nrPDB Length = 195 Score = 44.1 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 22/141 (15%), Positives = 45/141 (31%), Gaps = 29/141 (20%) Query: 183 YKLVRHVSFVDCPGH-----------------DILMSTMLSGAAVMDAALLLIAGNESCP 225 Y + FVD PG+ + S + LL+ G Sbjct: 64 YLVNSKYYFVDLPGYGYAKVSKKERMLWKRLVEDYFKNRWS----LQMVFLLVDGRIP-- 117 Query: 226 QPQTSEHLAA--IEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPI 283 PQ S+ + ++ + + I+ K+D ++ + + K + I+P Sbjct: 118 -PQDSDLMMVEWMKSLNIPFTIV-LTKMDKVKMSERAKKLEEHRKVF--SKYGEYTIIPT 173 Query: 284 SAQLKYNIDAVNEFIVKTIPV 304 S+ I + + I + Sbjct: 174 SSVTGEGISELLDLISTLLKE 194 >5LAD-A nrPDB Length = 404 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 27/154 (17%), Positives = 52/154 (33%), Gaps = 18/154 (11%) Query: 164 FKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDI---LMSTMLSGAA----VMDAALL 216 + V V+ VD PG D L + A D +L Sbjct: 35 SIVSEYAGTTTDPVYKSMELYPVGPVTLVDTPGLDDVGELGRLRVEKARRVFYRADCGIL 94 Query: 217 LIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIAD 276 + +S P P + + + M++ V++ NK+D++ E + + Sbjct: 95 V---TDSEPTPYEDDVVNLFKEMEIPFVVV-VNKIDVLG-----EKAEELKGLYESRY-- 143 Query: 277 GAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFM 310 A ++ +SA K D + + I + +P Sbjct: 144 EAKVLLVSALQKKGFDDIGKTISEILPGDEEIPY 177 >3IEU-A nrPDB Length = 301 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 48/133 (36%), Gaps = 10/133 (7%) Query: 183 YKLVRHVSFVDCPG-H----DILMSTMLSGAAVMDAAL-LLIAGNESCPQPQTSEHLAAI 236 + +VD PG H + M A+ + L+I E E + Sbjct: 52 TEGAYQAIYVDTPGLHMEEKRAINRLMNKAASSSIGDVELVIFVVEGTRWTPDDEMVLNK 111 Query: 237 EIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNE 296 VI+ NKVD ++E++ L L IVPISA+ N+D + Sbjct: 112 LREGKAPVILAVNKVDNVQEKADLLPHLQFLASQMNF----LDIVPISAETGLNVDTIAA 167 Query: 297 FIVKTIPVPPRDF 309 + K +P F Sbjct: 168 IVRKHLPEATHHF 180 >2CXX-A nrPDB Length = 190 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 36/214 (16%), Positives = 69/214 (32%), Gaps = 41/214 (19%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 I G GKST++ ++G + R K +T K+ K +K + Sbjct: 4 IIFAGRSNVGKSTLIYRLTGKKVRRGK---RPGVTRKIIEIEWKNHKIID---------- 50 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN- 221 P V F++ A +D A+L++ G Sbjct: 51 ----MPGFGFMMGLPKEVQERIKDEIVHFIE------------DNAKNIDVAVLVVDGKA 94 Query: 222 ---------ESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRG 272 + P E + + + I+ NK+D ++ + + + + Sbjct: 95 APEIIKRWEKRGEIPIDVEFYQFLRELDIP-TIVAVNKLDKIKNVQEVINFLAEKFEVPL 153 Query: 273 TIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPP 306 + D +PISA+ NI+ + I + I Sbjct: 154 SEIDKV-FIPISAKFGDNIERLKNRIFEVIRERQ 186 >3K53-A nrPDB Length = 271 Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 32/201 (15%), Positives = 76/201 (37%), Gaps = 41/201 (20%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + +G+ GK+T+ A++G+ R +T++ + + + P Y Sbjct: 6 VALVGNPNVGKTTIFNALTGL---RQHVGNWPGVTVEKKEGIMEYREKEFLVVDLPGIYS 62 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + +L+ +D G+ ++ ++ +M L Sbjct: 63 LTAHSID--------------ELIARNFILD--GNADVIVDIVDSTCLMRNLFL------ 100 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 T E + M++K++I++ NK DL++++ A K + K + G P++P Sbjct: 101 ------TLE----LFEMEVKNIILVLNKFDLLKKKGAKIDIKKMRKEL------GVPVIP 144 Query: 283 ISAQLKYNIDAVNEFIVKTIP 303 +A+ ++ + I Sbjct: 145 TNAKKGEGVEELKRMIALMAE 165 >2E87-A nrPDB Length = 357 Score = 42.2 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 70/205 (34%), Gaps = 43/205 (20%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + GH GKST+++A++ T K A+ D Y Sbjct: 170 VVIAGHPNVGKSTLLKALT---------------TAKPEIASYPFTTRGINVGQFEDGYF 214 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 ++ + + ++ + ++ + + +E Sbjct: 215 RYQIIDTPGLLDRPISERNEIEKQAILAL-------RYLGNLI---------IYIFDPSE 258 Query: 223 SCPQPQTSE-HL---AAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGA 278 C P + HL E L +++ NK+D+ E E+ K + KF++ + Sbjct: 259 HCGFPLEEQIHLFEEVHGEFKDLPFLVV-INKIDVADE----ENIKRLEKFVKEKGLNP- 312 Query: 279 PIVPISAQLKYNIDAVNEFIVKTIP 303 + ISA ID V E I+KT+ Sbjct: 313 --IKISALKGTGIDLVKEEIIKTLR 335 >3CLV-A nrPDB Length = 208 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 27/208 (12%), Positives = 68/208 (32%), Gaps = 7/208 (3%) Query: 95 INRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPT 154 + ++++ +G + GKS++V ++ T + N + + Sbjct: 2 MEKKSSYKTVLLGESSVGKSSIVLRLTK-DTFHENTNTTIGASFCTYVVNLNDINIKNNS 60 Query: 155 CPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAA 214 E + + +D + D G + S + A Sbjct: 61 NNEKNNNINSINDDNNVIITNQHNNYNENLCNIKFDIWDTAGQERYASIVPLYYRGATCA 120 Query: 215 LLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTI 274 +++ + S + + ++I +I++ NK+D + Q IL+ + Sbjct: 121 IVVFDISNSNTLDRAKTWVNQLKISSNYIIILVANKIDKN------KFQVDILEVQKYAQ 174 Query: 275 ADGAPIVPISAQLKYNIDAVNEFIVKTI 302 + + SA+ NI + + + I Sbjct: 175 DNNLLFIQTSAKTGTNIKNIFYMLAEEI 202 >3J8G-X nrPDB Length = 490 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 45/242 (18%), Positives = 72/242 (29%), Gaps = 42/242 (17%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 I + +G GKST+ I G ++ P Sbjct: 203 IKLAIVGRPNVGKSTLTNRILG---------------------EERVVVYDMPGTTRDSI 241 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 Y + D G R K D ++ T L + +L+I Sbjct: 242 YIPMERDGREYVLIDTAGVRKRGK------ITDAVEKFSVIKT-LQAIEDANVVMLVIDA 294 Query: 221 NESCPQPQTSEHLAAIEIMKL-KHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAP 279 E + I+ + ++I+ NK D + +E E K L F G I D A Sbjct: 295 REGISD---QDLSLLGFILNSGRSLVIVVNKWDGLSQE-VKEQVKETLDFRLGFI-DFAR 349 Query: 280 IVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGAEIEDLKGGVAG 339 + ISA + + E + R+ S V S +ED + + Sbjct: 350 VHFISALHGSGVGNLFESV--------REAYDSSTRRVGTSMLTRIMTMAVEDHQPPLVR 401 Query: 340 GS 341 G Sbjct: 402 GR 403 >1XZP-A nrPDB Length = 482 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 18/88 (20%), Positives = 36/88 (40%), Gaps = 12/88 (13%) Query: 211 MDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFI 270 D L ++ + + E +E +K K +++ NKVD++ K + I Sbjct: 324 ADIVLFVLDASSPLDE----EDRKILERIKNKRYLVVINKVDVVE--------KINEEEI 371 Query: 271 RGTIADGAPIVPISAQLKYNIDAVNEFI 298 + + +V ISA ++ + E I Sbjct: 372 KNKLGTDRHMVKISALKGEGLEKLEESI 399 >2WJG-A nrPDB Length = 188 Score = 39.5 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 27/182 (14%), Positives = 54/182 (29%), Gaps = 13/182 (7%) Query: 142 YANAKIYKCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLV-RHVSFVDCPGHDIL 200 Y A I + P G ++ VD PG L Sbjct: 8 YEIALIGNPNVGKSTIFNALTGENVYIGNWPGVTVEKKEGEFEYNGEKFKVVDLPGVYSL 67 Query: 201 MSTMLSGAAVMDAAL-----LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR 255 + + D + L++ ++ + + M ++++ NK+DL + Sbjct: 68 TANSIDEIIARDYIINEKPDLVVNIVDATALERNLYLTLQLMEMGA-NLLLALNKMDLAK 126 Query: 256 EESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRL 315 + K + G +VP+SA K I+ + + I + + P Sbjct: 127 SLGIEIDVDKLEKIL------GVKVVPLSAAKKMGIEELKKAISIAVKDKKTAEIKYPNF 180 Query: 316 IV 317 Sbjct: 181 EP 182 >1LNZ-A nrPDB Length = 342 Score = 38.7 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 29/81 (35%), Gaps = 9/81 (11%) Query: 236 IEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVN 295 + + + +I+ NK+D+ LE K L D P+ PISA + + + Sbjct: 270 LRLTERPQIIVA-NKMDMPEAAENLEAFKEKL-------TDDYPVFPISAVTREGLRELL 321 Query: 296 -EFIVKTIPVPPRDFMISPRL 315 E + P L Sbjct: 322 FEVANQLENTPEFPLYDEEEL 342 >3GEH-A nrPDB Length = 462 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 19/98 (19%), Positives = 35/98 (35%), Gaps = 13/98 (13%) Query: 207 GAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSI 266 A D LL I E +K + +I++ NK+DL+ ++ Sbjct: 300 AANTADLVLLTIDAATGWTTGDQE----IYEQVKHRPLILVMNKIDLVEKQLITS----- 350 Query: 267 LKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPV 304 + IV +A K ID++ I++ + Sbjct: 351 ----LEYPENITQIVHTAAAQKQGIDSLETAILEIVQT 384 >4HI0-E nrPDB Length = 199 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 36/217 (16%), Positives = 70/217 (32%), Gaps = 40/217 (18%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 + IG G V GK+ ++ A++ + + + IT + + C+ P Sbjct: 2 VKIGVCGPVGSGKTALIEALTRHMSKDYDMAV---ITNDIYTKEDAEFMCKNSVMPRERI 58 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAA---------VM 211 + + H F P ++L+ + SG + Sbjct: 59 IGVETGGCPHTAIREDASMNLEAVEEMHGRF---PNLELLL--IESGGDNLSATFNPELA 113 Query: 212 DAALLLIAGNESCPQPQ------TSEHLAAIEIMKLKHVIILQNKVDL-MREESALEHQK 264 D + +I E P+ T L + NK+DL + L+ + Sbjct: 114 DFTIFVIDVAEGDKIPRKGGPGITRSDLL------------VINKIDLAPYVGADLKVME 161 Query: 265 SILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKT 301 K +RG P + + + K +D V +I + Sbjct: 162 RDSKKMRGEK----PFIFTNIRAKEGLDDVIAWIKRN 194 >2F7S-A nrPDB Length = 217 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 23/154 (14%), Positives = 45/154 (29%), Gaps = 8/154 (5%) Query: 166 SDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCP 225 +K + Q P H+ D G + S + LL+ Sbjct: 63 REKRVVYNAQGPNGSSGKAFKVHLQLWDTAGQERFRSLTTAFFRDAMGFLLMFDLTSQQS 122 Query: 226 QPQTSEHLAAIEIMK---LKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 ++ ++ ++++ NK DL + E Q L G P Sbjct: 123 FLNVRNWMSQLQANAYCENPDIVLIGNKADLPDQREVNERQARELADKYG-----IPYFE 177 Query: 283 ISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLI 316 SA N++ E ++ I + ++ Sbjct: 178 TSAATGQNVEKAVETLLDLIMKRMEQCVEKTQIP 211 >1EK0-A nrPDB Length = 170 Score = 37.5 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 20/123 (16%), Positives = 42/123 (34%), Gaps = 4/123 (3%) Query: 184 KLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKH 243 + D G + S AAL++ + + + + K Sbjct: 49 EHTVKFEIWDTAGQERFASLAPMYYRNAQAALVVYDVTKPQSFIKARHWVKELHEQASKD 108 Query: 244 VIILQ--NKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKT 301 +II NK+D+++E + + + + SA+ N++ V I + Sbjct: 109 IIIALVGNKIDMLQEGGERKVAREEGEKLAEEKG--LLFFETSAKTGENVNDVFLGIGEK 166 Query: 302 IPV 304 IP+ Sbjct: 167 IPL 169 >5HXB-X nrPDB Length = 199 Score = 37.1 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 13/117 (11%), Positives = 37/117 (31%), Gaps = 16/117 (13%) Query: 322 DVNKPGAEIEDLKGGVAGGSILNGVFKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLF 381 + P + G V G + +G G ++ + P ++ + Sbjct: 4 PIRLPIVDKYKDMGTVVLGKLESGSICKGQQLVMMP-------------NKHNVEVLGIL 50 Query: 382 AEQNDLKFAVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLPNIYTDIEINYFLLR 438 ++ + PG + + K + + L G ++ +L + + ++ Sbjct: 51 SDDVETDTVAPGENLKIRLK---GIEEEEILPGFILCDPNNLCHSGRTFDAQIVIIE 104 >2QPT-A nrPDB Length = 550 Score = 37.1 bits (84), Expect = 0.018, Method: Composition-based stats. Identities = 25/185 (13%), Positives = 66/185 (35%), Gaps = 28/185 (15%) Query: 103 IGTIGHVAHGKSTVVRAI--SGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 + G + GK++ ++ + V R E + + + + + +P+ Sbjct: 68 VLVAGQYSTGKTSFIQYLLEQEVPGSRVGPEPTTDCFVAVMHGETEGTVPGNALVVDPEK 127 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAV---------- 210 + + + +++ +S +D PG +LSGA Sbjct: 128 PFRKLNPFGNTFLNRFMCAQLPNQVLESISIIDTPG-------ILSGAKQRVSRGYDFPA 180 Query: 211 --------MDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEH 262 +D +LL ++ + SE + A+ + K + ++ NK D++ + + Sbjct: 181 VLRWFAERVDLIILLFDAHKLEISDEFSEAIGALRGHEDK-IRVVLNKADMVETQQLMRV 239 Query: 263 QKSIL 267 +++ Sbjct: 240 YGALM 244 >1YVD-A nrPDB Length = 169 Score = 36.8 bits (83), Expect = 0.023, Method: Composition-based stats. Identities = 18/121 (14%), Positives = 37/121 (30%), Gaps = 9/121 (7%) Query: 186 VRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVI 245 + D G + + AA+++ + + + ++ Sbjct: 53 LHKFLIWDTAGQERFRALAPMYYRGSAAAIIVYDITKEETFSTLKNWVRELRQHGPPSIV 112 Query: 246 ILQ--NKVDLMREESALEHQKSILKFIRGTIAD-GAPIVPISAQLKYNIDAVNEFIVKTI 302 + NK DL +E + + A V SA+ NI+ + I + I Sbjct: 113 VAIAGNKCDLTDVREVME------RDAKDYADSIHAIFVETSAKNAININELFIEISRRI 166 Query: 303 P 303 P Sbjct: 167 P 167 >2WIC-A nrPDB Length = 267 Score = 36.4 bits (82), Expect = 0.029, Method: Composition-based stats. Identities = 23/218 (10%), Positives = 67/218 (30%), Gaps = 38/218 (17%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 +G IG+ GK+T+ ++G R + +T++ Q P Y Sbjct: 6 VGLIGNPNSGKTTLFNQLTG---ARQRVGNWAGVTVERKEGIFATTDHQVTLVDLPGTYS 62 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + S ++ H + D + ++ + Sbjct: 63 LTTISSQTSLD---------EQIACHYIL----------------SGDADMLINVVDASN 97 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 + + + ++ N +D+ ++ ++ + G P++P Sbjct: 98 LERNLYL---TLQLLELGIP-CVVALNMLDIAEKQQVRIDIDALAARL------GCPVIP 147 Query: 283 ISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRS 320 + + I+A+ + + + + P+ ++ + Sbjct: 148 LVSTRGRGIEALKIALDRHQANSDLELVHYPQPLLREA 185 >2IEZ-A nrPDB Length = 220 Score = 36.4 bits (82), Expect = 0.034, Method: Composition-based stats. Identities = 14/75 (18%), Positives = 26/75 (34%), Gaps = 5/75 (6%) Query: 242 KHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKT 301 ++++ NK DL + E Q L G P SA N++ E ++ Sbjct: 128 PDIVLIGNKADLPDQREVNERQARELAEKYG-----IPYFETSAATGQNVEKSVETLLDL 182 Query: 302 IPVPPRDFMISPRLI 316 I + ++ Sbjct: 183 IMKRMEKCVEKTQVP 197 >2IEY-A nrPDB Length = 195 Score = 36.4 bits (82), Expect = 0.036, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%), Gaps = 5/61 (8%) Query: 242 KHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKT 301 ++++ NK DL + E Q L G P SA N++ E ++ Sbjct: 128 PDIVLIGNKADLPDQREVNERQARELAEKYG-----IPYFETSAATGQNVEKSVETLLDL 182 Query: 302 I 302 I Sbjct: 183 I 183 >4V62-AB nrPDB Length = 510 Score = 35.6 bits (80), Expect = 0.051, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 52/150 (34%), Gaps = 22/150 (14%) Query: 23 PDIVEETEVVAQETQETQDADKPKKK-------------VAFTGLEEDGET-------EE 62 P E V+ + AD P ++ V+F G E +G+T + Sbjct: 360 PAFFESFPVILTDKNGVVKADIPFRRAESKYSFEQQGVTVSFYGGELNGQTFTDPPTVKS 419 Query: 63 EKRKREFEEGGGLPEQPLNPD-FSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVR-AI 120 RK F E + LN D + +P + GH+ HG T+ R Sbjct: 420 YARKAIFGEIFEFDTETLNSDGIFRTSPRGWFTFAHAVFALLFFFGHIWHGARTLFRDVF 479 Query: 121 SGVQTVRFKDELERNITIKLGYANAKIYKC 150 SG+ +++E K+G + + Sbjct: 480 SGIDPELSPEQVEWGFYQKVGDVTTRRKEA 509 >2X77-A nrPDB Length = 189 Score = 35.2 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 15/96 (15%), Positives = 37/96 (38%), Gaps = 5/96 (5%) Query: 212 DAALLLIAGNESCPQPQTSEHLAAI---EIMKLKHVIILQNKVDLMREESALEHQKSILK 268 DA + ++ + L A+ + ++ ++I NK DL S E + + Sbjct: 91 DAVIYVVDSTDRDRMGVAKHELYALLDEDELRKSLLLIFANKQDLPDAASEAEIAEQLG- 149 Query: 269 FIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPV 304 + + IV S++ + +++V+ + Sbjct: 150 -VSSIMNRTWTIVKSSSKTGDGLVEGMDWLVERLRE 184 >1UDX-A nrPDB Length = 416 Score = 34.8 bits (78), Expect = 0.094, Method: Composition-based stats. Identities = 32/204 (15%), Positives = 70/204 (34%), Gaps = 40/204 (19%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCY 161 ++G +G+ GKS+++ A++ K+ + Sbjct: 159 DVGLVGYPNAGKSSLLAAMTRAHP-------------KIAPYPFTTLSPNLGVVEVSEEE 205 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGN 221 R +D + G + +RH++ T + +L A + Sbjct: 206 RFTLADIPGIIEGASEGKGLGLEFLRHIA-----------RTRV-------LLYVLDAAD 247 Query: 222 ESCPQPQT--SEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAP 279 E +T E A + + ++ NKVDL+ EE+ ++ + +G Sbjct: 248 EPLKTLETLRKEVGAYDPALLRRPSLVALNKVDLLEEEAVKALADALAR-------EGLA 300 Query: 280 IVPISAQLKYNIDAVNEFIVKTIP 303 ++P+SA + A+ E + + Sbjct: 301 VLPVSALTGAGLPALKEALHALVR 324 >4MKI-B nrPDB Length = 298 Score = 34.5 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 30/85 (35%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 +G IGH GKST+++ ++G+ I I + K + Q + Y+ Sbjct: 40 VGIIGHTGSGKSTLIQQLNGLLKPSKGKIYINGIDITDKKVSLKDIRKQVGLVFQYPEYQ 99 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVR 187 F+ + V+ Sbjct: 100 LFEETVFKDIAFGPSNLGLSEEEVK 124 >3H2Y-A nrPDB Length = 368 Score = 34.5 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 26/148 (17%), Positives = 52/148 (35%), Gaps = 15/148 (10%) Query: 158 PDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALL- 216 Y S ++ CQR Y ++ VS D D + +L+G DA ++ Sbjct: 21 EVGYAPASSLEKEQVICQRCFRLKHYNEIQDVSLTD----DDFLR-ILNGIGKSDALVVK 75 Query: 217 LIAGNE--SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKF-IRGT 273 ++ + P + V+++ NK DL+ + + K +++ + Sbjct: 76 IVDIFDFNGSWLP------GLHRFVGNNKVLLVGNKADLIPKSVKHDKVKHWMRYSAKQL 129 Query: 274 IADGAPIVPISAQLKYNIDAVNEFIVKT 301 + ISA I + + I Sbjct: 130 GLKPEDVFLISAAKGQGIAELADAIEYY 157 >2WJI-A nrPDB Length = 165 Score = 34.1 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 33/207 (15%), Positives = 62/207 (29%), Gaps = 52/207 (25%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 I IG+ GKST+ A++G + Y Sbjct: 6 IALIGNPNVGKSTIFNALTG-----------------------------------ENVYI 30 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAAL-----LL 217 + K G VD PG L + + D + L+ Sbjct: 31 GNWPGVTVEKKEGEFEYNGE-----KFKVVDLPGVYSLTANSIDEIIARDYIINEKPDLV 85 Query: 218 IAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADG 277 + ++ + + M ++++ NK+DL + + K + G Sbjct: 86 VNIVDATALERNLYLTLQLMEMGA-NLLLALNKMDLAKSLGIEIDVDKLEKIL------G 138 Query: 278 APIVPISAQLKYNIDAVNEFIVKTIPV 304 +VP+SA K I+ + + I + Sbjct: 139 VKVVPLSAAKKMGIEELKKAISIAVKD 165 >4R98-A nrPDB Length = 271 Score = 34.1 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 25/199 (12%), Positives = 60/199 (30%), Gaps = 38/199 (19%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 IG IG+ GK+T+ ++G R + +T++ Q P Y Sbjct: 6 IGLIGNPNSGKTTLFNQLTG---SRQRVGNWAGVTVERKEGQFSTTDHQVTLVDLPGTYS 62 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 + S ++ H + D + ++ + Sbjct: 63 LTTISSQTSLD---------EQIACHYIL----------------SGDADLLINVVDASN 97 Query: 223 SCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVP 282 + + + I+ N +D+ +++ ++ + G P++P Sbjct: 98 LERNLYL---TLQLLELGIP-CIVALNMLDIAEKQNIRIEIDALSARL------GCPVIP 147 Query: 283 ISAQLKYNIDAVNEFIVKT 301 + A N+ V + + Sbjct: 148 LVATDTKNVQFVLKLAIDR 166 >2QU8-A nrPDB Length = 228 Score = 34.1 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 23/144 (15%), Positives = 48/144 (33%), Gaps = 14/144 (9%) Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDI--------LMSTMLSGAAVMDA 213 R+ + S + + +D PG + T ++ A ++ Sbjct: 51 RANVDVQSYSFTTKNLYVGHFDHKLNKYQIIDTPGLLDRAFENRNTIEMTTITALAHING 110 Query: 214 ALL-LIAGNESCPQPQTSEHLAAIEIMK----LKHVIILQNKVDLMREESALEHQKSILK 268 +L +I +E C E + +K K ++I NK+D +S K ++K Sbjct: 111 VILFIIDISEQCGLT-IKEQINLFYSIKSVFSNKSIVIGFNKIDKCNMDSLSIDNKLLIK 169 Query: 269 FIRGTIADGAPIVPISAQLKYNID 292 I + + S ++ Sbjct: 170 QILDNVKNPIKFSSFSTLTGVGVE 193 >4DCU-A nrPDB Length = 456 Score = 33.7 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 21/90 (23%), Positives = 38/90 (42%), Gaps = 4/90 (4%) Query: 216 LLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMR-EESALEHQKSILKFIRGTI 274 +++ G E + Q K V+I+ NK D + +ES ++ + ++ Sbjct: 283 VVLDGEEGIIE-QDKRIAGYAHEAG-KAVVIVVNKWDAVDKDESTMKEFEENIRDHFQF- 339 Query: 275 ADGAPIVPISAQLKYNIDAVNEFIVKTIPV 304 D API+ +SA K I + I+K Sbjct: 340 LDYAPILFMSALTKKRIHTLMPAIIKASEN 369 >6EHH-A nrPDB Length = 176 Score = 33.3 bits (74), Expect = 0.23, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 32/68 (47%), Gaps = 7/68 (10%) Query: 50 AFTGLEEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLSAEIINRQA--TINIGTIG 107 F G ++GET E+ KRE E GL L+ K+ +S E + ++I + Sbjct: 54 GFGGKVQEGETIEDGAKRELLEESGLSVDTLH----KVGHISFEFVGSPELMDVHIFSAD 109 Query: 108 HVAHGKST 115 HV HG T Sbjct: 110 HV-HGTPT 116 >4PHF-A nrPDB Length = 184 Score = 33.3 bits (74), Expect = 0.28, Method: Composition-based stats. Identities = 20/112 (17%), Positives = 37/112 (33%), Gaps = 9/112 (8%) Query: 193 DCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQT---SEHLAAIEIMKLKH---VII 246 D G + S ++ D +L+ + + + +I Sbjct: 66 DTAGQERFQSLGVAFYRGADCCVLVYDVTNASSFENIKSWRDEFLVHANVNSPETFPFVI 125 Query: 247 LQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFI 298 L NK+D E + +KS + + P+ SA+ N+D E I Sbjct: 126 LGNKIDA-EESKKIVSEKSAQELAKS--LGDIPLFLTSAKNAINVDTAFEEI 174 >5LEF-A nrPDB Length = 191 Score = 32.9 bits (73), Expect = 0.32, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 43/118 (36%), Gaps = 7/118 (5%) Query: 188 HVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIIL 247 + D G + S + S A+++ QT++ + + + VII+ Sbjct: 59 RLQLWDTAGLERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIM 118 Query: 248 Q--NKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIP 303 NK DL + Q SI + R + SA+ YN+ + + +P Sbjct: 119 LVGNKTDLAD-----KRQVSIEEGERKAKELNVMFIETSAKAGYNVKQLFRRVAAALP 171 >3ZYS-B nrPDB Length = 662 Score = 32.9 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 28/200 (14%), Positives = 63/200 (31%), Gaps = 36/200 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKD---------ELERNITIKLGYANAKIYKCQEP 153 I IG + GKS+V+ A+SGV R +L++ + + Sbjct: 73 IAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIE 132 Query: 154 TCPEPDCYRSFKSDK------EISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 + + + + + + V ++ +D PG ++ + G Sbjct: 133 ISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPG----ITRVAVG 188 Query: 208 AAVMDAALLLIAGNESCPQPQ---------------TSEHLAAIEIMKLK--HVIILQNK 250 D + + Q Q T+E L+ + + + I + K Sbjct: 189 NQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTK 248 Query: 251 VDLMREESALEHQKSILKFI 270 DL+ + + + + + Sbjct: 249 PDLVDKGTEDKVVDVVRNLV 268 >5DN8-A nrPDB Length = 446 Score = 32.9 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 31/201 (15%), Positives = 53/201 (26%), Gaps = 32/201 (15%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 I I IG GKST++ + G + V D+ T Y Sbjct: 179 IKIAMIGRPNVGKSTLINRLLGEERVIVYDQP--GTTRDSIYIPFARNDENYTLIDTAGI 236 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 R K + H D + L+ Sbjct: 237 RRRAKIQDYVEKFSMIKSLQAM--------------HA------------ADVVIFLLDA 270 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPI 280 + + Q L I + +II NK D + E + +I + + Sbjct: 271 RQGVTE-QDLRLLNRIVEAGVS-LIIAVNKWDGLNIEERDNVRNAIDRRMPFVDFARRYF 328 Query: 281 VPISAQLKYNIDAVNEFIVKT 301 + SA + + I ++ Sbjct: 329 I--SALHGTGVGKLFRAIQES 347 >5GTM-A nrPDB Length = 601 Score = 32.9 bits (73), Expect = 0.38, Method: Composition-based stats. Identities = 28/200 (14%), Positives = 63/200 (31%), Gaps = 36/200 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKD---------ELERNITIKLGYANAKIYKCQEP 153 I IG + GKS+V+ A+SGV R +L++ + + Sbjct: 41 IAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIE 100 Query: 154 TCPEPDCYRSFKSDK------EISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 + + + + + + V ++ +D PG ++ + G Sbjct: 101 ISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPG----ITRVAVG 156 Query: 208 AAVMDAALLLIAGNESCPQPQ---------------TSEHLAAIEIMKLK--HVIILQNK 250 D + + Q Q T+E L+ + + + I + K Sbjct: 157 NQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTK 216 Query: 251 VDLMREESALEHQKSILKFI 270 DL+ + + + + + Sbjct: 217 PDLVDKGTEDKVVDVVRNLV 236 >6FNP-B nrPDB Length = 300 Score = 32.5 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 33/239 (13%), Positives = 77/239 (32%), Gaps = 18/239 (7%) Query: 104 GTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYRS 163 IGH GKSTV + I+G+ D+ IT+ A +++ Sbjct: 55 ALIGHNGSGKSTVSKLINGLLAPDDLDKSS--ITVDGVKLGADTVWEVREKVGI--VFQN 110 Query: 164 FKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNES 223 + + + V P +++ ++ + D A S Sbjct: 111 PDNQFVGATVSDDVAFGLENRAVPR------PEMLKIVAQAVADVGMADYA----DSEPS 160 Query: 224 CPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPI 283 + +A I+ +K +I+ ++ M + E +++ I+ + Sbjct: 161 NLSGGQKQRVAIAGILAVKPQVIILDESTSMLDPEGKEQILDLVRKIKEDNNLTVISITH 220 Query: 284 SAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIVIRSFDVNKPGA----EIEDLKGGVA 338 + D V + + I P++ +++ ++ P ++ +G V Sbjct: 221 DLEEAAGADQVLVLDDGQLLDQGKPEEIFPKVEMLKRIGLDIPFVYRLKQLLKERGIVL 279 >2GIL-A nrPDB Length = 162 Score = 32.5 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 40/109 (36%), Gaps = 7/109 (6%) Query: 188 HVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIIL 247 + D G + S + S A+++ QT++ + + + VII+ Sbjct: 51 RLQLWDTAGQERFRSLIPSYIRDSTVAVVVYDITNVNSFQQTTKWIDDVRTERGSDVIIM 110 Query: 248 Q--NKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNIDAV 294 NK DL + Q SI + R + SA+ YN+ + Sbjct: 111 LVGNKTDLAD-----KRQVSIEEGERKAKELNVMFIETSAKAGYNVKQL 154 >4Z54-A nrPDB Length = 287 Score = 32.1 bits (71), Expect = 0.68, Method: Composition-based stats. Identities = 36/258 (13%), Positives = 68/258 (26%), Gaps = 30/258 (11%) Query: 90 LSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYK 149 + + + NI +G GKST+V + Q R R I I Sbjct: 9 MRKKTMKTGFDFNIMVVGQSGLGKSTLVNTLFKSQVSRKASSWNREEKIPKTVEIKAIGH 68 Query: 150 CQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMS---TMLS 206 E + + P + + + + Sbjct: 69 VIEEGGVKMKLTVIDTPGFGDQINNENCWEPIEKYINEQY--------EKFLKEEVNIAR 120 Query: 207 GAAVMD----AALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEH 262 + D L I+ +P E + + K+ ++I + K D M E E Sbjct: 121 KKRIPDTRVHCCLYFISPTGHSLRPLDLEFMKHLS--KVVNIIPVIAKADTMTLEEKSEF 178 Query: 263 QKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIPVPPRDFMISPRLIV--IRS 320 ++ + K + +G P +E + P +V + Sbjct: 179 KQRVRKELE---VNGIEFYPQK--------EFDEDLEDKTENDKIRQESMPFAVVGSDKE 227 Query: 321 FDVNKPGAEIEDLKGGVA 338 + VN G+ Sbjct: 228 YQVNGKRVLGRKTPWGII 245 >1IZL-B nrPDB Length = 472 Score = 31.8 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 32/88 (36%), Gaps = 2/88 (2%) Query: 65 RKREFEEGGGLPEQPLNPD-FSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVR-AISG 122 RK F E + LN D + +P + GH+ HG T+ R SG Sbjct: 384 RKAIFGEIFEFDTETLNSDGIFRTSPRGWFTFAHAVFALLFFFGHIWHGARTLFRDVFSG 443 Query: 123 VQTVRFKDELERNITIKLGYANAKIYKC 150 + +++E K+G + + Sbjct: 444 IDPELSPEQVEWGFYQKVGDVTTRRKEA 471 >1GA7-A nrPDB Length = 209 Score = 31.8 bits (70), Expect = 0.88, Method: Composition-based stats. Identities = 28/110 (25%), Positives = 46/110 (41%), Gaps = 14/110 (12%) Query: 17 LEPV-GEPDIVEETEVVAQETQETQDADKPKKKVAFTGLEEDGETEEEKRKREFEEGGGL 75 +PV E ++E+ + A +T ET P G+ E+GE+ E+ +RE E GL Sbjct: 65 FDPVRDEVVLIEQIRIAAYDTSET-----PWLLEMVAGMIEEGESVEDVARREAIEEAGL 119 Query: 76 PEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRAISGVQT 125 + P S L + +++I +G V T I G+ Sbjct: 120 IVKRTKPVLSFLASPGG--TSERSSI---MVGEVDA---TTASGIHGLAD 161 >3LRP-A nrPDB Length = 181 Score = 31.4 bits (69), Expect = 0.94, Method: Composition-based stats. Identities = 13/61 (21%), Positives = 24/61 (39%), Gaps = 3/61 (4%) Query: 209 AVMDAALLLIAGNESCPQPQTSE--HLAA-IEIMKLKHVIILQNKVDLMREESALEHQKS 265 + D + ++ N+ E H E +K +++ NK DL SA E + Sbjct: 83 SNTDGLIFVVDSNDRERIDDAREELHRMINEEELKDAIILVFANKQDLPNAMSAAEVTEK 142 Query: 266 I 266 + Sbjct: 143 L 143 >2GJ9-A nrPDB Length = 172 Score = 31.4 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 27/202 (13%), Positives = 65/202 (32%), Gaps = 42/202 (20%) Query: 101 INIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 + + G GKS+++ A++G E I + + + P Sbjct: 5 MKVVIAGRPNAGKSSLLNALAG---------REAAIVTDIAGTTRDVLREHIHIDGMPLH 55 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAG 220 +E S + +R G ++ + + M+ G DA + Sbjct: 56 IIDTAGLREASDEVERIGIERAWQEIEQ---------ADRVLFMVDGTTT-DA----VDP 101 Query: 221 NESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPI 280 E P+ + + +++NK D+ E + +G + Sbjct: 102 AEIWPE-------FIARLPAKLPITVVRNKADITGETLGMSEV------------NGHAL 142 Query: 281 VPISAQLKYNIDAVNEFIVKTI 302 + +SA+ +D + + +++ Sbjct: 143 IRLSARTGEGVDVLRNHLKQSM 164 >1YR7-A nrPDB Length = 262 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 29/185 (15%), Positives = 56/185 (30%), Gaps = 30/185 (16%) Query: 103 IGTIGHVAHGKSTVV----------RAISGVQTVRFKDELERNITIKLGYANAKIYKCQE 152 + +G GK+T+ ++ V EL +I + + Sbjct: 17 VVFVGTAGSGKTTLTGEFGRYLEDNYKVAYVNLDTGVKELPYEPSIDV--REFVTVEEIM 74 Query: 153 PTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPG-------HDILMSTML 205 P+ D+ + + R + +D PG H+ + M Sbjct: 75 REGYGPNGAIVESYDRLMEKFNEYLNKILRLEKENDYVLIDTPGQMETFLFHEFGVRLME 134 Query: 206 SGAAVMDAALLLIAGNES--CPQPQ----TSEHLAAIEIMKLKHVIILQNKVDLMREESA 259 + L++ ++ +P I++ I NKVDL+ EE Sbjct: 135 NLPYP-----LVVYISDPEILKKPNDYCFVRFFALLIDLRLGATTIPALNKVDLLSEEEK 189 Query: 260 LEHQK 264 H+K Sbjct: 190 ERHRK 194 >4HZU-A nrPDB Length = 279 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 24/179 (13%), Positives = 60/179 (33%), Gaps = 16/179 (8%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC-Y 161 + +GH GKST+ +++ G+ IT+ ++ + PD + Sbjct: 36 LAIVGHNGSGKSTLAKSLDGLLPFTQGSVTVGGITL-TPETVWQVREQIGMIFQNPDNQF 94 Query: 162 RSFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILM-------------STMLSGA 208 + +++ + + R + + G L+G Sbjct: 95 VGATVEDDVAFGLENRQISRDEMVPRVQAALAQVGMTSFAQREPSSLSGGQKQRVALAGI 154 Query: 209 AVMDAALLLIAGNESCPQPQTS-EHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSI 266 + +L++ S PQ E LA + ++ + + + + + E ++ + I Sbjct: 155 VAIAPKILILDEATSMLDPQGRIEMLAIVRQLRQQQNLTVISITHDIDEAASADRVLVI 213 >5B3F-A nrPDB Length = 343 Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 31/80 (38%), Gaps = 14/80 (17%) Query: 87 LNPLSAEI---------INRQATI-NIGTIGHVAHGKSTVVRAISGVQTVRFKDELERNI 136 L P + + I + IG G GKST RAIS + F +EL +I Sbjct: 14 LVPRGSHMSQPENFREVIRHSPLVYLIGVAGDSGSGKSTFTRAISDI----FGEELVSSI 69 Query: 137 TIKLGYANAKIYKCQEPTCP 156 T+ + + + + P Sbjct: 70 TVDDYHLYDRKTRSEMGITP 89 >4P4S-B nrPDB Length = 346 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 28/200 (14%), Positives = 63/200 (31%), Gaps = 36/200 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKD---------ELERNITIKLGYANAKIYKCQEP 153 I IG + GKS+V+ A+SGV R +L++ + + Sbjct: 31 IAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIE 90 Query: 154 TCPEPDCYRSFKSDK------EISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 + + + + + + V ++ +D PG ++ + G Sbjct: 91 ISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPG----ITRVAVG 146 Query: 208 AAVMDAALLLIAGNESCPQPQ---------------TSEHLAAIEIMKLK--HVIILQNK 250 D + + Q Q T+E L+ + + + I + K Sbjct: 147 NQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTK 206 Query: 251 VDLMREESALEHQKSILKFI 270 DL+ + + + + + Sbjct: 207 PDLVDKGTEDKVVDVVRNLV 226 >4P4S-A nrPDB Length = 303 Score = 30.6 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 28/200 (14%), Positives = 63/200 (31%), Gaps = 36/200 (18%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKD---------ELERNITIKLGYANAKIYKCQEP 153 I IG + GKS+V+ A+SGV R +L++ + + Sbjct: 16 IAVIGDQSSGKSSVLEALSGVALPRGSGIVTRCPLVLKLKKLVNEDKWRGKVSYQDYEIE 75 Query: 154 TCPEPDCYRSFKSDK------EISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSG 207 + + + + + + V ++ +D PG ++ + G Sbjct: 76 ISDASEVEKEINKAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPG----ITRVAVG 131 Query: 208 AAVMDAALLLIAGNESCPQPQ---------------TSEHLAAIEIMKLK--HVIILQNK 250 D + + Q Q T+E L+ + + + I + K Sbjct: 132 NQPADIGYKIKTLIKKYIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTK 191 Query: 251 VDLMREESALEHQKSILKFI 270 DL+ + + + + + Sbjct: 192 PDLVDKGTEDKVVDVVRNLV 211 >1T9H-A nrPDB Length = 307 Score = 30.2 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 10/68 (14%), Positives = 25/68 (36%) Query: 209 AVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKVDLMREESALEHQKSILK 268 +D A+L+ + + + + II K+DL+ ++ + ++ + Sbjct: 85 CNVDQAVLVFSAVQPSFSTALLDRFLVLVEANDIQPIICITKMDLIEDQDTEDTIQAYAE 144 Query: 269 FIRGTIAD 276 R D Sbjct: 145 DYRNIGYD 152 >1EFP-B nrPDB Length = 252 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 21/103 (20%), Positives = 43/103 (41%), Gaps = 11/103 (10%) Query: 208 AAVMDAALLLIAGNESCPQPQTSEHLAAIEIM-------KLKHVIILQNKVDLMREESAL 260 A D A+L++A ++ Q E LA +I+ + +I + +D + Sbjct: 77 AMGADRAILVVAADD---VQQDIEPLAVAKILAAVARAEGTELIIAGKQAID-NDMNATG 132 Query: 261 EHQKSILKFIRGTIADGAPIVPISAQLKYNIDAVNEFIVKTIP 303 + +IL + + T A I A++ +D + I ++P Sbjct: 133 QMLAAILGWAQATFASKVEIEGAKAKVTREVDGGLQTIAVSLP 175 >5NKM-B nrPDB Length = 317 Score = 29.8 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 11/52 (21%), Positives = 26/52 (50%), Gaps = 1/52 (1%) Query: 82 PDFSKLNPLSAEIINRQATINIGT-IGHVAHGKSTVVRAISGVQTVRFKDEL 132 DF +++ ++++ N+ + IG GKST++ ++G + + E Sbjct: 9 TDFGEISDAISDLLTSSPNFNVISAIGPQGAGKSTLLSMLAGNNSRQMYREY 60 >4G1U-C nrPDB Length = 266 Score = 29.8 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 22/128 (17%), Positives = 38/128 (29%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDCYR 162 + IG GKST++R ++G + + + A + Sbjct: 40 VAIIGPNGAGKSTLLRLLTGYLSPSHGECHLLGQNLNSWQPKALARTRAVMRQYSELAFP 99 Query: 163 SFKSDKEISPKCQRPGCPGRYKLVRHVSFVDCPGHDILMSTMLSGAAVMDAALLLIAGNE 222 S+ + G R L + ++ DC +LSG L + Sbjct: 100 FSVSEVIQMGRAPYGGSQDRQALQQVMAQTDCLALAQRDYRVLSGGEQQRVQLARVLAQL 159 Query: 223 SCPQPQTS 230 PQP Sbjct: 160 WQPQPTPR 167 >4YLG-A nrPDB Length = 173 Score = 29.4 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 24/55 (43%), Gaps = 3/55 (5%) Query: 215 LLLIAGNESCPQPQTSEHLAAI---EIMKLKHVIILQNKVDLMREESALEHQKSI 266 + ++ N+ + E L + + M+ +++ NK DL + S E + + Sbjct: 85 IFVVDSNDRDRIGEAREELMKMLNEDEMRNAILLVFANKHDLPQAMSISEVTEKL 139 >6N8N-W nrPDB Length = 640 Score = 29.4 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 27/108 (25%), Positives = 43/108 (39%), Gaps = 21/108 (19%) Query: 54 LEEDGETEEEKRKREFEEGGGLPEQPLNPDFSKLNPLS----AEIINRQAT--------- 100 LE+ E E+ R+++FEE K+ LS E+ +A Sbjct: 272 LEKQKEMGEDYREQDFEEADKEGFDADEKVMEKVKILSIDQLEELFLSKAPNEPLLPPLP 331 Query: 101 -----INIGTIGHVAHGKSTVVRAISG---VQTVRFKDELERNITIKL 140 INIG +G+ GKS+ + ++ G V + + TIKL Sbjct: 332 GQPPLINIGLVGYPNVGKSSTINSLVGAKKVSVSSTPGKTKHFQTIKL 379 >2YV5-A nrPDB Length = 302 Score = 29.1 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 35/70 (50%), Gaps = 5/70 (7%) Query: 233 LAAIEIMKLKHVIILQNKVDLMREESALEHQKSILKFIRGTIADGAPIVPISAQLKYNID 292 L E K++ VI+ NK+DL+ E +K + ++I G ++ +SA+ ID Sbjct: 103 LVVYEYFKVEPVIVF-NKIDLL----NEEEKKELERWISIYRDAGYDVLKVSAKTGEGID 157 Query: 293 AVNEFIVKTI 302 + +++ I Sbjct: 158 ELVDYLEGFI 167 >1VIA-A nrPDB Length = 175 Score = 29.1 bits (63), Expect = 4.6, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 17/29 (58%) Query: 102 NIGTIGHVAHGKSTVVRAISGVQTVRFKD 130 NI IG + GKST+ RA++ + F D Sbjct: 6 NIVFIGFMGSGKSTLARALAKDLDLVFLD 34 >4V03-A nrPDB Length = 257 Score = 29.1 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 33/211 (15%), Positives = 64/211 (30%), Gaps = 31/211 (14%) Query: 99 ATINIGTIGHVAHGKSTVVRAISGVQTVRFK-------DELERNITIKLGYAN---AKIY 148 A + + T G GK+T+ I K D RN+ + LG N I Sbjct: 2 AEVIVITSGKGGVGKTTLTANIGTALAKLGKKVLLIDADIGLRNLDMILGLENRIVYDIL 61 Query: 149 KCQEPTCPEPDCYRSFKSDKEISPKCQRPGCPGRYKLVRH---------------VSFVD 193 E P K + + VD Sbjct: 62 DVLEGRVPYEKALVKDKRGLSLWLLPANQRANKDVIDIEKWNKTVEEIKNSGNYDYILVD 121 Query: 194 CPGHDILMSTMLSGAAVMDAALLLIAGNESCPQPQTSEHLAAIEIMKLKHVIILQNKV-- 251 P + + D AL+++ S + + +E M ++ ++ N++ Sbjct: 122 SP--AGIEKGFQIAVSPADKALIVVNPEVSSIRDADRV-IGLLESMDKRNYKVIVNRIKW 178 Query: 252 DLMREESALEHQKSILKFIRGTIADGAPIVP 282 ++++ + L + I+ ++ I P P Sbjct: 179 EMVKRGAMLS-VEDIVDILKAEIIGIIPEEP 208 >5WDH-A nrPDB Length = 376 Score = 29.1 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 17/35 (48%), Gaps = 2/35 (5%) Query: 390 AVPGGLIGVGTKVDPTLCRADRLVGQVVGAKGHLP 424 + PGG T++ +L R+D G + GA P Sbjct: 49 SGPGGPSDPPTRL--SLSRSDERRGTLSGAPAPPP 81 >5JB3-6 nrPDB Length = 113 Score = 28.7 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 10/50 (20%), Positives = 23/50 (46%) Query: 347 FKLGDEIEIRPGIVTKDDKGKIQCKPIFSNIVSLFAEQNDLKFAVPGGLI 396 ++GD + ++P V D +G I + + + L + + + GG + Sbjct: 61 IRVGDLVIVQPWPVQSDKRGDIVYRYTQTQVDWLLRKGKITQEFLTGGSL 110 >5DGX-A nrPDB Length = 256 Score = 28.7 bits (62), Expect = 6.4, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 33/77 (42%), Gaps = 1/77 (1%) Query: 61 EEEKRKREF-EEGGGLPEQPLNPDFSKLNPLSAEIINRQATINIGTIGHVAHGKSTVVRA 119 E+E +E + G + + L+ F + LS ++ +A + +G GK+T+ Sbjct: 4 EKETGSKELAKVDGNVTIKDLSFAFGEHKVLSGVSVDIKAGQTVAFVGKSGSGKTTLTSI 63 Query: 120 ISGVQTVRFKDELERNI 136 IS T + L + Sbjct: 64 ISRFYTQHEGEILLDGV 80 >4A9A-A nrPDB Length = 376 Score = 28.3 bits (61), Expect = 7.8, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 21/36 (58%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVRFKDELERNITI 138 +G +G + GKST++ ++G ++ + E +T+ Sbjct: 75 VGFVGFPSVGKSTLLSKLTGTESEAAEYEFTTLVTV 110 >5JSZ-B nrPDB Length = 287 Score = 28.3 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 14/91 (15%), Positives = 30/91 (32%), Gaps = 2/91 (2%) Query: 103 IGTIGHVAHGKSTVVRAISGVQ--TVRFKDELERNITIKLGYANAKIYKCQEPTCPEPDC 160 I +GH GKST+++ + + T + IT + G K + + + Sbjct: 36 IALVGHTGSGKSTLMQHFNALLKPTSGKIEIAGYTITPETGNKGLKDLRRKVSLAFQFSE 95 Query: 161 YRSFKSDKEISPKCQRPGCPGRYKLVRHVSF 191 + F++ + R + Sbjct: 96 AQLFENTVLKDVEYGPRNFGFSEDEAREAAL 126 >5X7K-A nrPDB Length = 268 Score = 28.3 bits (61), Expect = 9.8, Method: Composition-based stats. Identities = 11/25 (44%), Positives = 15/25 (60%) Query: 103 IGTIGHVAHGKSTVVRAISGVQTVR 127 +G IG A GKST+ R + G+ V Sbjct: 41 LGIIGPSASGKSTLARLLVGIWPVS 65 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.118 0.297 Lambda K H 0.267 0.0366 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,587,160 Number of Sequences: 36641 Number of extensions: 668725 Number of successful extensions: 2837 Number of sequences better than 10.0: 161 Number of HSP's better than 10.0 without gapping: 149 Number of HSP's successfully gapped in prelim test: 94 Number of HSP's that attempted gapping in prelim test: 2265 Number of HSP's gapped (non-prelim): 342 length of query: 527 length of database: 10,336,785 effective HSP length: 102 effective length of query: 425 effective length of database: 6,599,403 effective search space: 2804746275 effective search space used: 2804746275 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 61 (28.3 bits)