BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P32419 (343 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5ZI4-A nrPDB 692 0.0 1MLD-A nrPDB 253 7e-68 4WLE-A nrPDB 251 4e-67 1SMK-A nrPDB 238 4e-63 4E0B-A nrPDB 205 3e-53 1IE3-A nrPDB 204 3e-53 6BAL-A nrPDB 186 2e-47 3P7M-A nrPDB 86 2e-17 1HYE-A nrPDB 84 8e-17 4PLW-A nrPDB 84 9e-17 3TL2-A nrPDB 83 1e-16 1UXJ-A nrPDB 83 2e-16 3GVH-A nrPDB 83 2e-16 2HJR-A nrPDB 82 2e-16 4BGV-A nrPDB 82 4e-16 4ROS-A nrPDB 80 1e-15 1GV0-A nrPDB 77 1e-14 1GUZ-A nrPDB 75 5e-14 4PLF-A nrPDB 75 6e-14 1A5Z-A nrPDB 74 6e-14 3NEP-X nrPDB 73 2e-13 3FI9-A nrPDB 71 5e-13 2X0J-A nrPDB 69 3e-12 4L4S-H nrPDB 69 3e-12 1PZF-A nrPDB 67 2e-11 9LDB-A nrPDB 67 2e-11 6H9S-A nrPDB 65 3e-11 5NFR-A nrPDB 65 4e-11 4UUP-A nrPDB 65 5e-11 5NQB-A nrPDB 64 9e-11 6CT6-A nrPDB 64 1e-10 2V65-A nrPDB 64 1e-10 1SOW-A nrPDB 64 1e-10 3ZZN-A nrPDB 63 2e-10 4AJN-A nrPDB 63 2e-10 1Y6J-A nrPDB 63 2e-10 1V6A-A nrPDB 62 4e-10 4LN1-A nrPDB 61 7e-10 2V6B-A nrPDB 60 1e-09 4ND4-A nrPDB 60 1e-09 1LDM-A nrPDB 59 2e-09 1LTH-T nrPDB 59 4e-09 4Q3N-A nrPDB 58 6e-09 4I1I-A nrPDB 58 6e-09 5K0Z-A nrPDB 57 1e-08 1CIV-A nrPDB 57 1e-08 6IHE-A nrPDB 55 5e-08 4M1Q-A nrPDB 54 1e-07 2D4A-B nrPDB 54 1e-07 4KDE-A nrPDB 53 1e-07 1T24-A nrPDB 52 3e-07 6CEP-A nrPDB 52 3e-07 5NUE-A nrPDB 52 4e-07 3D0O-A nrPDB 52 5e-07 5HTO-A nrPDB 51 7e-07 3PQF-A nrPDB 50 1e-06 1OC4-A nrPDB 50 1e-06 5MDH-A nrPDB 50 1e-06 4UUO-A nrPDB 49 2e-06 3WSV-A nrPDB 49 4e-06 6J9S-A nrPDB 48 5e-06 4BGU-A nrPDB 47 2e-05 7MDH-A nrPDB 45 4e-05 4UUM-A nrPDB 45 4e-05 4JCO-A nrPDB 44 1e-04 2LDB-A nrPDB 43 2e-04 1EZ4-A nrPDB 41 8e-04 1B8U-A nrPDB 40 0.001 3DL2-A nrPDB 40 0.002 3D5T-A nrPDB 37 0.010 4TVO-A nrPDB 37 0.018 5ZF1-A nrPDB 33 0.13 4ARE-A nrPDB 30 1.1 2Y6I-A nrPDB 30 1.2 6H1E-A nrPDB 30 1.3 3QB0-A nrPDB 30 1.3 6APE-A nrPDB 30 1.5 5CEF-A nrPDB 29 2.8 2NVK-X nrPDB 29 3.8 2BE7-D nrPDB 28 4.3 4B9V-A nrPDB 28 7.5 3EH7-A nrPDB 28 7.6 1RVY-A nrPDB 27 9.8 >5ZI4-A nrPDB Length = 345 Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 343/343 (100%), Positives = 343/343 (100%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD Sbjct: 3 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 62 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV Sbjct: 63 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 122 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK Sbjct: 123 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 182 Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA Sbjct: 183 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 242 Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV Sbjct: 243 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 302 Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 343 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL Sbjct: 303 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 345 >1MLD-A nrPDB Length = 314 Score = 253 bits (647), Expect = 7e-68, Method: Compositional matrix adjust. Identities = 149/340 (43%), Positives = 207/340 (60%), Gaps = 36/340 (10%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61 KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY + Sbjct: 2 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQ 61 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 + + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P+A I +ISNPVN Sbjct: 62 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPDAMICIISNPVN 121 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181 S +PI E KK G + P + GVT LD+VRA F+ + L ++ V Sbjct: 122 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLDPARV-----------SV 170 Query: 182 TVIGGHSGETIIPIITDKS--LVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 VIGGH+G+TIIP+I+ + + F D Q R+Q G E+VKAK GAGSATLSMA+ Sbjct: 171 PVIGGHAGKTIIPLISQCTPKVDFPQD-QLSTLTGRIQEAGTEVVKAKAGAGSATLSMAY 229 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNG 298 AGA+F ++ + + ++ E +FV K+Q+ YFS P++L + G Sbjct: 230 AGARFVFSLVDAMNGKEGVVE--CSFV---------KSQE----TDCPYFSTPLLLGKKG 274 Query: 299 SVVSIDTSV-LEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 I+ ++ + K+SP EE+++ A+ EL+ +I+KG+ F+ Sbjct: 275 ----IEKNLGIGKISPFEEKMIAEAIPELKASIKKGEEFV 310 >4WLE-A nrPDB Length = 340 Score = 251 bits (640), Expect = 4e-67, Method: Compositional matrix adjust. Identities = 149/340 (43%), Positives = 207/340 (60%), Gaps = 36/340 (10%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61 KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY + Sbjct: 28 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQ 87 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 + + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P A I VI+NPVN Sbjct: 88 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVN 147 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181 S +PI E KK G + P + GVT LD+VRA TF+ + L ++ V Sbjct: 148 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARV-----------NV 196 Query: 182 TVIGGHSGETIIPIITDKS--LVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 VIGGH+G+TIIP+I+ + + F D Q R+Q G E+VKAK GAGSATLSMA+ Sbjct: 197 PVIGGHAGKTIIPLISQCTPKVDFPQD-QLTALTGRIQEAGTEVVKAKAGAGSATLSMAY 255 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNG 298 AGA+F ++ + + ++ E +FV K+Q+ YFS P++L + G Sbjct: 256 AGARFVFSLVDAMNGKEGVVE--CSFV---------KSQE----TECTYFSTPLLLGKKG 300 Query: 299 SVVSIDTSV-LEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 I+ ++ + K+S EE++++ A+ EL+ +I+KG+ F+ Sbjct: 301 ----IEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFV 336 >1SMK-A nrPDB Length = 326 Score = 238 bits (606), Expect = 4e-63, Method: Compositional matrix adjust. Identities = 144/338 (42%), Positives = 204/338 (60%), Gaps = 32/338 (9%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61 KVAILGA+GG+GQPL++L+K++P VS L LYD+ A G+ D+SH++T + G+ + Sbjct: 10 KVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQ 69 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 +E L+ ++++PAGVPRKPG+TRDDLFK+NAGIVK+L + K P A + +ISNPVN Sbjct: 70 LEAALTGMDLIIVPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPRAIVNLISNPVN 129 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181 S VPIA E KK G + P ++GVT LD+VRA TF+ + L L +P+ V Sbjct: 130 STVPIAAEVFKKAGTYDPKRLLGVTMLDVVRANTFVAEVLGL-DPR----------DVDV 178 Query: 182 TVIGGHSGETIIPIITD-KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240 V+GGH+G TI+P+++ K ++ + R+Q GG E+V+AK GAGSATLSMA+A Sbjct: 179 PVVGGHAGVTILPLLSQVKPPSSFTQEEISYLTDRIQNGGTEVVEAKAGAGSATLSMAYA 238 Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNGS 299 KFA+ LR + E AFV + Q+ + +F+ + L RNG Sbjct: 239 AVKFADACLRGLRGDAGVIE--CAFV----------SSQV---TELPFFASKVRLGRNGI 283 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 + L L+ E + A KEL +IEKG SFI Sbjct: 284 E---EVYSLGPLNEYERIGLEKAKKELAGSIEKGVSFI 318 >4E0B-A nrPDB Length = 313 Score = 205 bits (521), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 136/338 (40%), Positives = 193/338 (57%), Gaps = 31/338 (9%) Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDK 59 +KVA++GA+GG+GQ L+LLLK P S+LALYDI G+ DLSHI T+ S GY Sbjct: 4 MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTHVSIKGYAG 63 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + L A VVLI AGV RKPG+ R DLF +NAGIVKSL + PNA I +I+NP Sbjct: 64 EDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACIGIITNP 123 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 VN+ VPIA E LKK G + + GVT LD++R+ETF+ + LK GQ+ + Sbjct: 124 VNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAE---LK----GQDPGEV---- 172 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 +V VIGGHSG TI+P+++ V D++ R+Q G E+V+AK G GSATLSM Sbjct: 173 RVPVIGGHSGVTILPLLSQVEGVEFSDEEIAALTKRIQNAGTEVVEAKAGGGSATLSMGQ 232 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 A +F ++++ E+ + + Y+ G NG+ A +F+ P+ L Sbjct: 233 AACRFGLALVKALQGEE-----VIEYAYVEG--NGEHAS---------FFAQPVKLGKEG 276 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V I +LS E+ ++ ++ L +I+ G F+ Sbjct: 277 VEEILP--YGELSDFEKAALDGMLETLNSDIQIGVDFV 312 >1IE3-A nrPDB Length = 312 Score = 204 bits (520), Expect = 3e-53, Method: Compositional matrix adjust. Identities = 134/338 (39%), Positives = 190/338 (56%), Gaps = 30/338 (8%) Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDK 59 +KVA+LGA+GG+GQ L+LLLK P SEL+LYDI G+ DLSHI T G+ Sbjct: 1 MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSG 60 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + L A VVLI AGV RKPG+ R DLF +NAGIVK+LV V K P A I +I+NP Sbjct: 61 EDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNP 120 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 VN+ V IA E LKK G + + GVT LD++ + TF+ + LK + G+ + Sbjct: 121 VNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIICSNTFVAE---LKGKQPGEVE------- 170 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 V VIGGHSG TI+P+++ V +++ R+Q G E+V+AK G GSATLSM Sbjct: 171 -VPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQ 229 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 A A+F ++R+ E+ E Y+ G +G+ A+ +FS P++L Sbjct: 230 AAARFGLSLVRALQGEQGVVEC----AYVEG--DGQYAR---------FFSQPLLLGKNG 274 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V + + LS E+ + + L+K+I G+ F+ Sbjct: 275 VE--ERKSIGTLSAFEQNALEGMLDTLKKDIALGQEFV 310 >6BAL-A nrPDB Length = 335 Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust. Identities = 135/338 (39%), Positives = 191/338 (56%), Gaps = 31/338 (9%) Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDK 59 +KVA+LGA+GG+GQ L+LLLKL P ++L+LYDI G+ D+SHI T + G+ Sbjct: 25 MKVAVLGAAGGIGQALALLLKLQLPAGTDLSLYDIAPVTPGVAVDVSHIPTAVNVKGFSG 84 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + L A VVLI AGV RKPG+ R DLF +NAGIV+ L+ V P A + +I+NP Sbjct: 85 EDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRGLIEKVAVTCPKACVGIITNP 144 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 VN+ V IA E LKK G + + GVT LD++R+ETF+ + LK G +T+ Sbjct: 145 VNTTVAIAAEVLKKAGVYDKRKLFGVTTLDVLRSETFVAE---LK----GLNVSRTS--- 194 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 V VIGGHSG TI+P+++ + + E R+Q G E++ AK G GSATLSMA Sbjct: 195 -VPVIGGHSGVTILPLLSQVQYAKWNEDEIEPLTKRIQNAGTEVLNAKAGGGSATLSMAQ 253 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 A A+FA +++ E++ Y+ G +GK A+ +FS P+ L Sbjct: 254 AAARFARSLVKGLSG-----ETVVECTYVEG--DGKYAR---------FFSQPVRLGKEG 297 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V I + LS E+Q + + LR +IE G+ FI Sbjct: 298 VEEILP--IGPLSNFEQQALENMLPTLRADIELGEKFI 333 >3P7M-A nrPDB Length = 321 Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 85/281 (30%), Positives = 135/281 (48%), Gaps = 36/281 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K+ ++GA G +G L+ L L + ++ L+DI GK L + T G D Sbjct: 7 KITLVGA-GNIGGTLAHL-ALIKQLGDVVLFDIAQGMPNGKALDLLQT-CPIEGVDFKVR 63 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + L N+ VV++ AGVPRKPG++RDDL +N +++++ + PNA ++ I+N Sbjct: 64 GTNDYKDLENSDVVIVTAGVPRKPGMSRDDLLGINIKVMQTVGEGIKHNCPNAFVICITN 123 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++ I V L+K ++G+ LD R TFL D L N + Q Q Sbjct: 124 PLD----IMVNMLQKFSGVPDNKIVGMAGVLDSARFRTFLADEL---NVSVQQVQ----- 171 Query: 178 HRKVTVIGGHSGETIIPIITDKSL----VFQLDKQ-------YEHFIHRVQFGGDEIVKA 226 V+GGH G+T++P+ ++ + QL K+ + + R + GG EIV A Sbjct: 172 ---AYVMGGH-GDTMVPLTKMSNVAGVSLEQLVKEGKLKQERLDAIVSRTRSGGGEIV-A 226 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVY 267 GSA + A AG + AE L+ P + A +Y Sbjct: 227 LLKTGSAYYAPAAAGIQMAESFLKDKKMILPCAAKVKAGMY 267 >1HYE-A nrPDB Length = 313 Score = 84.0 bits (206), Expect = 8e-17, Method: Compositional matrix adjust. Identities = 82/283 (28%), Positives = 138/283 (48%), Gaps = 44/283 (15%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL----YDIRAAEGIGKDL--SHINTNSSCV 55 +KV I+GASG VG +LLL P++ +L L + I EG+ +D+ + T S Sbjct: 1 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60 Query: 56 GY-DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 Y + D + + VV+I +GVPRK G++R DL K NA IV + + + +I Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEIC-DTKIF 119 Query: 115 VISNPVNSLVPIAVETLKKM--GKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQE 171 VI+NPV+ V T K + KF+ V G+ T+LD +R + + + G Sbjct: 120 VITNPVD------VMTYKALVDSKFERNQVFGLGTHLDSLRFKVAIAKFF-------GVH 166 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHF--------IHRVQFGGDEI 223 D+ + +IG H G++++P+++ S+ +++E F I V+ G++I Sbjct: 167 IDEV----RTRIIGEH-GDSMVPLLSATSIGGIPIQKFERFKELPIDEIIEDVKTKGEQI 221 Query: 224 VKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFV 266 ++ K G+ F A V+R N + +LSA+V Sbjct: 222 IRLKGGS-------EFGPAAAILNVVRCIVNNEKRLLTLSAYV 257 >4PLW-A nrPDB Length = 326 Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 81/281 (28%), Positives = 138/281 (49%), Gaps = 42/281 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56 K++++GA G +G L+ L+ + ++ L+DI GK D+SH + +N G Sbjct: 6 KISLIGA-GNIGGTLAHLIA-QKELGDVVLFDIVEGMPQGKALDISHSSPIMGSNVKITG 63 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + + + VV+I AG+PRKPG++RDDL +NA I+K + + K+ PNA ++V+ Sbjct: 64 TNN---YEDIKGSDVVIITAGIPRKPGMSRDDLLSVNAKIMKDVAENIKKYCPNAFVIVV 120 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175 +NP++ +V + L K V G+ LD R FL + L + + Sbjct: 121 TNPLDVMVYV----LHKYSGLPHNKVCGMAGVLDSSRFRYFLAEKLNVSPNDV------- 169 Query: 176 TMHRKVTVIGGHSGETIIPIITDKSL----VFQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231 + VIGGH G+T++P+ ++ + + KQ +I + + DEIV+ + AG Sbjct: 170 ----QAMVIGGH-GDTMVPLTRYCTVGGIPLTEFIKQ--GWITQEEI--DEIVERTRNAG 220 Query: 232 SA------TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFV 266 T S FA A A E+ S+ +K SA++ Sbjct: 221 GEIVNLLKTGSAYFAPAASAIEMAESYLKDKKRILPCSAYL 261 >3TL2-A nrPDB Length = 315 Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust. Identities = 86/280 (30%), Positives = 132/280 (47%), Gaps = 37/280 (13%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI--GKDLSHINTNSSCVGYDKD 60 KV+++GA G G + LL ++++ L DI E GK L + S G+D + Sbjct: 10 KVSVIGA-GFTGATTAFLLA-QKELADVVLVDIPQLENPTKGKALDMLEA-SPVQGFDAN 66 Query: 61 SIENT----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 I + +++ VV+I AG+ RKPG++RDDL N+ I+KS+ + K +PNA I+V+ Sbjct: 67 IIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVL 126 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQ 170 +NPV+++ K+ G F V+G + LD R TF+ L L I G Sbjct: 127 TNPVDAM---TYSVFKEAG-FPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGG 182 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGA 230 D + + GG ET+IP ++ E + R + GG EIV G Sbjct: 183 HGDDMVPLVRYSYAGGIPLETLIP-----------KERLEAIVERTRKGGGEIV-GLLGN 230 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPG 270 GSA + A + + E +L K + L A YL G Sbjct: 231 GSAYYAPAASLVEMTEAIL------KDQRRVLPAIAYLEG 264 >1UXJ-A nrPDB Length = 309 Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 98/348 (28%), Positives = 163/348 (46%), Gaps = 56/348 (16%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI--GKDLSHINTNSSCVGYD-- 58 K++I+GA G VG + L + + ++ L DI EG+ GK L + S G+D Sbjct: 4 KISIIGA-GFVGSTTAHWLA-AKELGDIVLLDI--VEGVPQGKAL-DLYEASPIEGFDVR 58 Query: 59 ---KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115 ++ +T +N+ V+++ +G PRKPG++R+DL K+NA I ++ ++ +PNA I++ Sbjct: 59 VTGTNNYADT-ANSDVIVVTSGAPRKPGMSREDLIKVNADITRACISQAAPLSPNAVIIM 117 Query: 116 ISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDK 174 ++NP++++ +A E + F V+G LD R TF I E Sbjct: 118 VNNPLDAMTYLAAE----VSGFPKERVIGQAGVLDAARYRTF-----------IAMEAGV 162 Query: 175 TTMHRKVTVIGGHSGETI-IPIITDKSLV----FQLDKQYEHFIHRVQFGGDEIVKAKQG 229 + + ++GGH E + +P + S + F + + R + GG EIV + Sbjct: 163 SVKDVQAMLMGGHGDEMVPLPRFSTISGIPVSEFIAPDRLAQIVERTRKGGGEIVNLLK- 221 Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYF 289 GSA + A A A+ E VL+ P YL G G N I YF Sbjct: 222 TGSAYYAPAAATAQMVEAVLKDKKRVMP------VAAYLTG---------QYGLNDI-YF 265 Query: 290 SLPIVLRNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRKNIEKGKSF 336 +P++L G V +LE L+ E L+N + K +R ++ KS Sbjct: 266 GVPVILGAGGV----EKILELPLNEEEMALLNASAKAVRATLDTLKSL 309 >3GVH-A nrPDB Length = 324 Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 79/277 (28%), Positives = 133/277 (48%), Gaps = 36/277 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD-KDS 61 K+A++G SG +G L+ L L + ++ L+DI GK L I +S G+D K + Sbjct: 9 KIALIG-SGMIGGTLAHLAGLKE-LGDVVLFDIAEGTPQGKGLD-IAESSPVDGFDAKFT 65 Query: 62 IEN---TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 N + A VV++ AGVPRKPG++RDDL +N +++ + + K+AP A ++ I+N Sbjct: 66 GANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITN 125 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++++ V L+K V+G+ LD R FL +E + + Sbjct: 126 PLDAM----VWALQKFSGLPAHKVVGMAGVLDSARFRYFL-----------SEEFNVSVE 170 Query: 178 HRKVTVIGGHSGETIIPIITDKSLV-----------FQLDKQYEHFIHRVQFGGDEIVKA 226 V V+GGH G++++P+ ++ + + + I R + GG EIV Sbjct: 171 DVTVFVLGGH-GDSMVPLARYSTVAGIPLPDLVKMGWTSQDKLDKIIQRTRDGGAEIVGL 229 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLS 263 + GSA + A + + AE L+ P LS Sbjct: 230 LK-TGSAFYAPAASAIQMAESYLKDKKRVLPVAAQLS 265 >2HJR-A nrPDB Length = 328 Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust. Identities = 99/353 (28%), Positives = 163/353 (46%), Gaps = 57/353 (16%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINT--NSSCVGYD 58 K++I+GA G +G ++LLL + ++ ++DI +G DL+H S + Sbjct: 16 KISIIGA-GQIGSTIALLLGQKD-LGDVYMFDIIEGVPQGKALDLNHCMALIGSPAKIFG 73 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 +++ E L N+ VV+I AGVPRKP +TR DL +NA IV S+ VGK+ PNA ++ I+N Sbjct: 74 ENNYE-YLQNSDVVIITAGVPRKPNMTRSDLLTVNAKIVGSVAENVGKYCPNAFVICITN 132 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++++ V K+ V G++ LD R L L +K + Sbjct: 133 PLDAM----VYYFKEKSGIPANKVCGMSGVLDSARFRCNLSRALGVKPSDV--------- 179 Query: 178 HRKVTVIGGHSGETIIPIITDKSL--VFQLD---------KQYEHFIHRVQFGGDEIVKA 226 V+GGH G+ +IP+ + ++ + D Q I + FGG EIV+ Sbjct: 180 --SAIVVGGH-GDEMIPLTSSVTIGGILLSDFVEQGKITHSQINEIIKKTAFGGGEIVEL 236 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286 + GSA + A + A+ L K L YL G N Sbjct: 237 LK-TGSAFYAPAASAVAMAQAYL------KDSKSVLVCSTYLTGQYNVNNL--------- 280 Query: 287 EYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338 + +P+V+ +NG I+ V+ LS E+ L + +V+ ++ ++ KS L Sbjct: 281 -FVGVPVVIGKNG----IEDVVIVNLSDDEKSLFSKSVESIQNLVQDLKSLNL 328 >4BGV-A nrPDB Length = 323 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 77/280 (27%), Positives = 136/280 (48%), Gaps = 40/280 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD-- 60 K++++GA G VG ++ L + ++ ++DI GK L I + GYD D Sbjct: 4 KISVIGA-GAVGATVAQTLAIRQ-TGDIYIFDIVDGLAEGKALD-ILEGAPHWGYDLDIK 60 Query: 61 -------SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARI 113 S + + V+++ AG+ RKPG++RDDL N GI+KS+ A+ K++P ++I Sbjct: 61 GFCTADESKYAEMKGSDVIVVTAGLARKPGMSRDDLLLKNIGIMKSVGEAIKKYSPESKI 120 Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQ 172 +V++NP + I + K P ++G+ +LD R TFL QE Sbjct: 121 VVVTNPAD----IMAYAIYKASGISPERIIGLGGSLDSTRFRTFL-----------AQEL 165 Query: 173 DKTTMHRKVTVIGGHSGETIIPII--TDKSLVFQLD----KQYEHFIHRVQFGGDEIVKA 226 + + VIGGH G+ ++P I ++ S + D ++ + + R +FGG EIV Sbjct: 166 NVSFEDVNAFVIGGH-GDDMVPFIRYSNVSGIPIEDLLPREKIDEIVKRTRFGGGEIVNL 224 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFV 266 + GSA + + A E ++ N++ +A++ Sbjct: 225 YK-TGSAFYAPGISIAVMVESIV----NDRKRVIPCAAYI 259 >4ROS-A nrPDB Length = 320 Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 81/296 (27%), Positives = 139/296 (46%), Gaps = 28/296 (9%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD-- 60 K+A++GA G +G L+ L L + ++ L+DI GK L I ++ G+D Sbjct: 5 KIALIGA-GQIGGTLAHLAGLKE-LGDVVLFDIVDGVPQGKALD-IAESAPVDGFDAKYS 61 Query: 61 --SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 S + ++ A VV++ AGVPRKPG++RDDL +N +++++ + + AP+A ++ I+N Sbjct: 62 GASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGAGIKEHAPDAFVICITN 121 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI------GQE 171 P++++ V L+K V+G+ LD R FL + + + G Sbjct: 122 PLDAM----VWALQKFSGLPTNKVVGMAGVLDSARFRHFLAEEFGVSVEDVTAFVLGGHG 177 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231 D + R TV G +P+ L + ++ + + R + GG EIV + G Sbjct: 178 DDMVPLTRYSTVAG-------VPLTDLVKLGWTTQEKLDAMVERTRKGGGEIVNLLK-TG 229 Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE 287 SA + A + AE LR P L + GL G ++G+N +E Sbjct: 230 SAFYAPAASAIAMAESYLRDKKRVLPCAAYLDGQYGIDGLYVG--VPVVIGENGVE 283 >1GV0-A nrPDB Length = 310 Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 79/261 (30%), Positives = 129/261 (49%), Gaps = 34/261 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +K+ ++GA G VG + L EL L D+ EGI + + S VG Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDV--VEGIPQGKALDMYESGPVGLFDTK 57 Query: 62 IENT-----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + + +N+ +V+I AG+PRKPG+TR+DL MNAGIV+ + + + + N I+V+ Sbjct: 58 VTGSNDYADTANSDIVVITAGLPRKPGMTREDLLSMNAGIVREVTGRIMEHSKNPIIVVV 117 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175 SNP++ + +A +K G K V+G+ LD R +F+ L + QD T Sbjct: 118 SNPLDIMTHVA---WQKSGLPKE-RVIGMAGVLDSARFRSFIAMELGVSM------QDVT 167 Query: 176 TMHRKVTVIGGHSGETIIPIITDKSL----VFQL--DKQYEHFIHRVQFGGDEIVKA-KQ 228 V+GGH G+ ++P++ ++ V L ++ + R + GG EIV KQ Sbjct: 168 A-----CVLGGH-GDAMVPVVKYTTVAGIPVADLISAERIAELVERTRTGGAEIVNHLKQ 221 Query: 229 GAGSATLSMAFAGAKFAEEVL 249 GSA S A + + E ++ Sbjct: 222 --GSAFYSPATSVVEMVESIV 240 >1GUZ-A nrPDB Length = 310 Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust. Identities = 84/327 (25%), Positives = 149/327 (45%), Gaps = 40/327 (12%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +K+ ++GA G VG + L EL L D+ EGI + + S VG Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDV--VEGIPQGKALDMYESGPVGLFDTK 57 Query: 62 IENT-----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + + +N+ +V+I AG+PRKPG+TR+DL NAGIVK + + K + N I+V+ Sbjct: 58 VTGSNDYADTANSDIVIITAGLPRKPGMTREDLLMKNAGIVKEVTDNIMKHSKNPIIIVV 117 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 SNP++ + +A + K + + GV LD R +F I E + Sbjct: 118 SNPLDIMTHVA-WVRSGLPKERVIGMAGV--LDAARFRSF-----------IAMELGVSM 163 Query: 177 MHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKA-KQG 229 V+GGH G+ ++P++ ++ + + + R + GG EIV+ KQ Sbjct: 164 QDINACVLGGH-GDAMVPVVKYTTVAGIPISDLLPAETIDKLVERTRNGGAEIVEHLKQ- 221 Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSA-------FVYLPGLKNGKKAQQLVG 282 GSA + A + + E ++ P L FV +P +K G+ + + Sbjct: 222 -GSAFYAPASSVVEMVESIVLDRKRVLPCAVGLEGQYGIDKTFVGVP-VKLGRNGVEQIY 279 Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLE 309 + +++ L ++ ++ +V + +LE Sbjct: 280 EINLDQADLDLLQKSAKIVDENCKMLE 306 >4PLF-A nrPDB Length = 334 Score = 74.7 bits (182), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 97/347 (27%), Positives = 162/347 (46%), Gaps = 60/347 (17%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH----INTNSSCVG 56 K++++G SG +G ++ L + ++ L+D+ +G DLSH +TN G Sbjct: 10 KISLIG-SGMIGGTMAYLCA-QKELGDVVLFDVVKNMPQGKALDLSHSSSIADTNVKVTG 67 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111 +S E+ + + VV+I AG+ + PG +RDDL NA I++ + + K+ PNA Sbjct: 68 --TNSYED-IKGSDVVIITAGLTKAPGKSDKEWSRDDLLPFNAKIMREVGENIKKYCPNA 124 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPK---- 167 ++VI+NP++ +V + E + K K + GV LD R F+ + L + +P+ Sbjct: 125 FVIVITNPLDVMVKVLHEH-SGLPKNKVCGMAGV--LDSSRFRHFIAEKLNV-SPRDVQA 180 Query: 168 --IGQEQDKTT-MHRKVTVIGGHSGETIIPI--ITDKSLVFQLDKQYEHFIHRVQFGGDE 222 IG DK + R VTV G IP+ K + Q ++ + + R + G E Sbjct: 181 MVIGAHGDKMVPLTRYVTVNG-------IPLQEFIKKGRITQ--EEIDEIVERTKNAGGE 231 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 IV G GSA + A + + AE L K + L YL G K Sbjct: 232 IVNL-LGQGSAYFAPAASAIEMAEAYL------KDKKRVLVCSCYLEGQYGHKDM----- 279 Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRK 328 + +P V+ V V+E +L+P E++L + +V+E+RK Sbjct: 280 -----FVGVPAVIGGNGV----EKVIELELTPEEKELFDKSVEEVRK 317 >1A5Z-A nrPDB Length = 319 Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust. Identities = 83/279 (29%), Positives = 131/279 (46%), Gaps = 36/279 (12%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHIN--TNSSCVGY 57 +K+ I+G G VG + L + + E+ L D+ + AEG DL H T + + Y Sbjct: 1 MKIGIVGL-GRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANI-Y 58 Query: 58 DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 D + L + VV++ AGVP+KPG TR L NA ++K + V K+AP++ ++V++ Sbjct: 59 AGDYAD--LKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVT 116 Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPK------IGQ 170 NPV+ L LK+ G P V G T LD R T + + +P+ IG+ Sbjct: 117 NPVDVLTYF---FLKESG-MDPRKVFGSGTVLDTARLRTLIAQHCGF-SPRSVHVYVIGE 171 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLD-KQYEHFIHRVQFGGDEIVKAKQG 229 D +IGG IP+ + + D K E+F + + EI++ K Sbjct: 172 HGDSEVPVWSGAMIGG------IPLQNMCQVCQKCDSKILENFAEKTKRAAYEIIERK-- 223 Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYL 268 G+ ++A A A E + F +EK L+ VYL Sbjct: 224 -GATHYAIALAVADIVESI---FFDEK---RVLTLSVYL 255 >3NEP-X nrPDB Length = 314 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 31/235 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +KV ++GA G VG ++ + E+ + DI+ GK L + +S G+D Sbjct: 1 MKVTVIGA-GNVGATVAECVARQDVAKEVVMVDIKDGMPQGKALD-MRESSPIHGFDT-R 57 Query: 62 IENT-----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + T ++ V +I AG+PR PG++RDDL N IV + + +P++ I+V+ Sbjct: 58 VTGTNDYGPTEDSDVCIITAGLPRSPGMSRDDLLAKNTEIVGGVTEQFVEGSPDSTIIVV 117 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175 +NP++ + +A E F VMG+ LD R +F I +E D + Sbjct: 118 ANPLDVMTYVAYEA----SGFPTNRVMGMAGVLDTGRFRSF-----------IAEELDVS 162 Query: 176 TMHRKVTVIGGHSGETIIPIITDKSL----VFQL--DKQYEHFIHRVQFGGDEIV 224 + ++GGH G+T++P+ ++ V QL D + E + R + G EIV Sbjct: 163 VRDVQALLMGGH-GDTMVPLPRYTTVGGIPVPQLIDDARIEEIVERTKGAGGEIV 216 >3FI9-A nrPDB Length = 343 Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust. Identities = 61/237 (25%), Positives = 110/237 (46%), Gaps = 26/237 (10%) Query: 3 KVAILGASGGVGQPLS---LLLKLSPYVSELALYDIRAA--EGIGKDLSHINTNSSCVGY 57 K+ I+GA+G +G ++ +++L+P L LYD A EG+ +++ H + + Sbjct: 10 KLTIVGAAGMIGSNMAQTAAMMRLTP---NLCLYDPFAVGLEGVAEEIRHCGFEGLNLTF 66 Query: 58 DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNAR-ILVI 116 D I+ L++A+ ++ G PRK G+TR+DL K NA I L + + P+ + +++I Sbjct: 67 TSD-IKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIII 125 Query: 117 SNP--VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDK 174 NP + LV + L KP V + LD R ++ L + +K + + Sbjct: 126 FNPADITGLVTLIYSGL------KPSQVTTLAGLDSTRLQSELAKHFGIKQSLVTNTRTY 179 Query: 175 TTMHRKVTVIGGHSGETIIPII----TDKSLVFQLDKQYEHFIHRVQFGGDEIVKAK 227 ++ V + P+ TDK ++Q+ RV GG I+K + Sbjct: 180 GGHGEQMAVFASTAKVNGTPLTDLIGTDK----LTNEQWAELKQRVVKGGANIIKLR 232 >2X0J-A nrPDB Length = 294 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 71/235 (30%), Positives = 114/235 (48%), Gaps = 35/235 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCV 55 +K+ +GA G VG + L+ V E+AL DI +G+ DL+H I+ V Sbjct: 1 MKLGFVGA-GRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIV 59 Query: 56 GYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115 G S+ L ++++++ AG+ RKPG+TR DL NAGI+K + + + AP ++ILV Sbjct: 60 GGADYSL---LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILV 116 Query: 116 ISNPVNSLVPIAVETLKKMGKFKPGN-VMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173 ++NP++ + I K+ G KP N V G+ N LD R + L + Sbjct: 117 VTNPMDVMTYI---MWKESG--KPRNEVFGMGNQLDSQRLKERLYNA------------- 158 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLV-FQLDKQYEHFIHRVQFGGDEIVKAK 227 R+ +IG H + KSL F + +E + V+F E++K K Sbjct: 159 GARNIRRAWIIGEHGDSMFVA----KSLADFDGEVDWEAVENDVRFVAAEVIKRK 209 >4L4S-H nrPDB Length = 339 Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust. Identities = 72/269 (26%), Positives = 124/269 (46%), Gaps = 32/269 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH----INTNSSCVG 56 K+ ++G G VG ++ + + ELAL D+ +G DL H + T G Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSG 79 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 D N +N+++V+I AG ++ G +R +L + N I K ++ V K++PN ++L++ Sbjct: 80 KDY----NVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIV 135 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQ 170 SNPV+ L +A K+ F V+G NLD R E V L +G+ Sbjct: 136 SNPVDILTYVAW----KISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGE 191 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPII-TDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQ 228 D + + G S +T+ P + TDK DK+ +H+ V E++K K Sbjct: 192 HGDSSVPVWSGMNVAGVSLKTLHPDLGTDK------DKEQWKEVHKQVVESAYEVIKLK- 244 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKP 257 G + ++ + A AE ++++ P Sbjct: 245 --GYTSWAIGLSVADLAESIMKNLRRVHP 271 >1PZF-A nrPDB Length = 331 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 67/247 (27%), Positives = 113/247 (45%), Gaps = 45/247 (18%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHI----NTNSSCVG 56 KVA++G SG +G + L L ++++ LYD+ EG DLSH+ +TN S Sbjct: 11 KVAMIG-SGMIGGTMGYLCALRE-LADVVLYDVVKGMPEGKALDLSHVTSVVDTNVSVRA 68 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111 + S E L+ A V++ AG+ + PG +R+DL N+ I++ + + K+ P Sbjct: 69 --EYSYEAALTGADCVIVTAGLTKVPGKPDSEWSRNDLLPFNSKIIREIGQNIKKYCPKT 126 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMG--VTNLDLVRAETFLVDYLMLKNPKIG 169 I+V++NP++ +V + E P N++ LD R ++ D L + + Sbjct: 127 FIIVVTNPLDCMVKVMCEA-----SGVPTNMICGMACMLDSGRFRRYVADALSVSPRDV- 180 Query: 170 QEQDKTTMHRKVTVIGGHSGETIIPI---ITDKSLVFQ--------LDKQYEHFIHRVQF 218 + TVIG H G+ ++P+ IT Q +KQ E + Sbjct: 181 ----------QATVIGTH-GDCMVPLVRYITVNGYPIQKFIKDGVVTEKQLEEIAEHTKV 229 Query: 219 GGDEIVK 225 G EIV+ Sbjct: 230 SGGEIVR 236 >9LDB-A nrPDB Length = 332 Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 84/335 (25%), Positives = 152/335 (45%), Gaps = 64/335 (19%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56 K+ ++G G VG ++ + + E+AL D+ + G+ DL H + T G Sbjct: 22 KITVVGV-GAVGMACAISILMKELADEIALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 D N +N+++V+I AG ++ G +R +L + N I K ++ + K++PN ++LV+ Sbjct: 81 KDY----NVTANSRLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCKLLVV 136 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKT 175 SNPV+ L +A K+ F V+G NLD R YLM G+ Sbjct: 137 SNPVDILTYVA----WKISGFPKNRVIGSGCNLDSARFR-----YLM------GERLGVH 181 Query: 176 TMHRKVTVIGGHSGETIIPI--------ITDKSLVFQL----DKQYEHFIHR-VQFGGDE 222 + ++G H G++ +P+ ++ K+L +L DK++ +H+ V E Sbjct: 182 PLSCHGWILGEH-GDSSVPVWSGVNVAGVSLKNLHPELGTDADKEHWKAVHKEVVDSAYE 240 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 ++K K G + ++ + A AE ++++ P + + L G+K Sbjct: 241 VIKLK---GYTSWAIGLSVADLAESIMKNLRRVHPISTMIKG---LYGIKENV------- 287 Query: 283 DNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREE 316 + S+P +L +NG I V L+P EE Sbjct: 288 -----FLSVPCILGQNG----ISDVVKVTLTPEEE 313 >6H9S-A nrPDB Length = 307 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 60/198 (30%), Positives = 93/198 (46%), Gaps = 24/198 (12%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDK 59 +K++I+G +G VG + L + E+ LYD+ AEG DL H T + K Sbjct: 1 MKISIIG-TGRVGSSTAFALINAAVADEIVLYDLNKEMAEGEALDLLHATT------FHK 53 Query: 60 DSI-----ENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 I + + + +VLI AG +KPG TR DL NA I+K + + K+APN I+ Sbjct: 54 RMIIRAGEYSDIEGSDIVLITAGAAQKPGETRLDLTIKNAKIIKGISENIKKYAPNTLII 113 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFL-----VDYLMLKNPKI 168 I+NPV+ + + + K+ F+ V+G T LD R + V + + I Sbjct: 114 NITNPVDVMSYV----VWKVTGFESNRVIGTGTILDTARLRALIGKNCGVSPMSVHAYII 169 Query: 169 GQEQDKTTMHRKVTVIGG 186 G+ D +IGG Sbjct: 170 GEHGDSELAAWSSAMIGG 187 >5NFR-A nrPDB Length = 320 Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 28/202 (13%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHINT----NSSC 54 M K+A++G SG +G + L L + +L LYD+ +G DL H +T N + Sbjct: 1 MTKIALIG-SGQIGAIVGELCLLEN-LGDLILYDVVPGIPQGKALDLKHFSTILGVNRNI 58 Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 +G ++ IE+ + +A +++I AGV RK G+TR+DL +N I+KS+ +V A ++ Sbjct: 59 LGTNQ--IED-IKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVI 115 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173 +SNP++ I V K + G+ LD R + + D L K+ E Sbjct: 116 CVSNPLD----IMVNVFHKFSNLPHEKICGMAGILDTSRYCSLIADKL-----KVSAED- 165 Query: 174 KTTMHRKVTVIGGHSGETIIPI 195 ++GGH G+ ++P+ Sbjct: 166 -----VNAVILGGH-GDLMVPL 181 >4UUP-A nrPDB Length = 341 Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust. Identities = 67/246 (27%), Positives = 106/246 (43%), Gaps = 34/246 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE----LALYDI----RAAEGIGKDLSHINTNSS 53 + V I GA+G +G L+ + + L L +I +A EG+ +L + Sbjct: 5 IHVLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTL 64 Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNAR 112 D E + V + PRKPG+ R DL + NAGI K A+ ++A P + Sbjct: 65 AGVVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVK 124 Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172 +LV+ NP N+ IA+ K+G P N +T LD RA + K+G Sbjct: 125 VLVVGNPANTNCLIAMANAPKLG---PENFSAMTRLDHNRAIGEIA-------AKLGVPV 174 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITD---------KSLVFQLDKQY--EHFIHRVQFGGD 221 DK V V G HS T +P ++ K + L K+Y F+ ++ G Sbjct: 175 DKV---HNVVVWGNHS-NTQVPDVSHATVDKEGGTKKVSDALPKEYLEGEFVQKIAQRGG 230 Query: 222 EIVKAK 227 +++A+ Sbjct: 231 AVIEAR 236 >5NQB-A nrPDB Length = 332 Score = 63.9 bits (154), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 69/268 (25%), Positives = 122/268 (45%), Gaps = 30/268 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56 K+ ++G G VG ++ + + ELAL D+ + G+ DL H + T G Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 D + +N+++V+I AG ++ G +R +L + N I K ++ V K++P+ ++LV+ Sbjct: 81 KDY----SVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPHCKLLVV 136 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQ 170 SNPV+ L +A K+ F V+G NLD R E V L +G+ Sbjct: 137 SNPVDILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWILGE 192 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQG 229 D + + G S +T+ P L DK+ +H+ V E++K K Sbjct: 193 HGDSSVPVWSGMNVAGVSLKTLHP-----ELGTDADKEQWKQVHKQVVDSAYEVIKLK-- 245 Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKP 257 G + ++ + A AE ++++ P Sbjct: 246 -GYTSWAIGLSVADLAESIMKNLRRVHP 272 >6CT6-A nrPDB Length = 338 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 78/268 (29%), Positives = 129/268 (48%), Gaps = 39/268 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVG---- 56 K+A++G SG +G ++ L L + ++ L+D+ +GK DL H NSS V Sbjct: 11 KIALVG-SGMIGGTMAFLCSLKE-LGDVVLFDVVPNMPMGKAMDLCH---NSSVVDNGIT 65 Query: 57 -YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPN 110 Y +S E L+NA VV+I AG+ + PG +R DL +N I++ + A+ K+ PN Sbjct: 66 VYGSNSYE-CLTNADVVIITAGITKIPGKSDKEWSRMDLLPVNIKIMREVGGAIKKYCPN 124 Query: 111 ARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLM-----LKN 165 A I+ I+NP++ +V AV+ + K + G+ LD R + D L ++ Sbjct: 125 AFIINITNPLDVMVA-AVQEAANVPKHMICGMAGM--LDSSRLRRMIADCLHVSPHDVQG 181 Query: 166 PKIGQEQDKTT-MHRKVTVIGGHSGETIIPI--ITDKSLVFQLDKQYEHFIHRVQFGGDE 222 IG D + R +T+ G IPI +K L+ + D + ++ + G + Sbjct: 182 MVIGVHGDNMLPLMRYITING-------IPIQEFINKGLINKED--INNIYNKTKQAGGD 232 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLR 250 IV+ G GSA + + AE L+ Sbjct: 233 IVRL-LGQGSAYYAPGTSAILMAESYLK 259 >2V65-A nrPDB Length = 331 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 84/324 (25%), Positives = 152/324 (46%), Gaps = 59/324 (18%) Query: 17 LSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYDKDSIENTLSNAQVV 72 +S+LLK ELA+ D+ + G+ DL H + + VG DKD + +N++VV Sbjct: 37 ISILLK--DLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIVG-DKDY--SVTANSKVV 91 Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132 ++ AG ++ G +R +L + N I K ++ + K++PN ++V+SNPV+ L +A Sbjct: 92 VVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVA----W 147 Query: 133 KMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGET 191 K+ F V+G TNLD R + + L L +P ++ H ++G H G++ Sbjct: 148 KLSGFPRHRVIGSGTNLDSARFRHLIGEKLHL-HP--------SSCH--AWIVGEH-GDS 195 Query: 192 IIPI--------ITDKSLVFQL----DKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMA 238 +P+ ++ + L Q+ D + IH+ V G E++K K G + ++ Sbjct: 196 SVPVWSGVNVAGVSLQGLNPQMGTEGDGENWKAIHKEVVDGAYEVIKLK---GYTSWAIG 252 Query: 239 FAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNG 298 + A E ++++ H P +S V Q + G + S+P VL N Sbjct: 253 MSVADLVESIIKNMHKVHP----VSTLV-----------QGMHGVKDEVFLSVPCVLGNS 297 Query: 299 SVVSIDTSVLEKLSPREEQLVNTA 322 + + L+ + E+QL +A Sbjct: 298 GLTDVIHMTLK--AEEEKQLQKSA 319 >1SOW-A nrPDB Length = 328 Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 74/291 (25%), Positives = 127/291 (43%), Gaps = 51/291 (17%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDL------SHINTNSSCVG 56 K+A++G SG +G + L L ++++ L+D+ GK L S +TN S Sbjct: 10 KIAMIG-SGMIGGTMGYLCVLRE-LADVVLFDVVTGMPEGKALDDSQATSIADTNVSVTS 67 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111 ++ ++ + VV+I AG+ + PG +R+DL NA I++ + V K+ P A Sbjct: 68 ANQ---YEKIAGSDVVIITAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKYCPLA 124 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQ 170 ++V++NP++ + V+ + V G+ N LD R F+ D L + I Sbjct: 125 FVIVVTNPLDCM----VKCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPRDI-- 178 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPI---ITDKSLVFQ--------LDKQYEHFIHRVQFG 219 + TVIG H G+ ++P+ +T + + + + R + Sbjct: 179 ---------QATVIGTH-GDHMLPLARYVTVNGFPLREFIKKGKMTEAKLAEIVERTKKA 228 Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPG 270 G EIV+ G GSA + A + A+ L K E L VY G Sbjct: 229 GGEIVRL-LGQGSAYYAPALSAITMAQAFL------KDEKRVLPCSVYCQG 272 >3ZZN-A nrPDB Length = 310 Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 57/193 (29%), Positives = 89/193 (46%), Gaps = 14/193 (7%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDK 59 +KV I+G SG VG + L L E+ L D+ + A+ +D+ H + V Sbjct: 1 MKVGIVG-SGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWA 59 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 S + L A+ V++ AGV ++PG TR L NA + +V V + AP A +LV +NP Sbjct: 60 GSYGD-LEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNP 118 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKI-----GQEQD 173 V+ + +A + PG V+G T LD R L +YL + + G+ D Sbjct: 119 VDVMTQVA----YALSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGD 174 Query: 174 KTTMHRKVTVIGG 186 + +GG Sbjct: 175 SEVLVWSSAQVGG 187 >4AJN-A nrPDB Length = 331 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 71/273 (26%), Positives = 128/273 (46%), Gaps = 40/273 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH--INTNSSCVGYD 58 K+ ++G G VG ++ + + ELAL D+ +G DL H + + + Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSS 79 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 KD + +N+++V+I AG ++ G +R +L + N I K ++ V K++P ++L++SN Sbjct: 80 KDY--SVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSN 137 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 PV+ L +A K+ F V+G NLD R YLM G+ + Sbjct: 138 PVDILTYVA----WKISGFPKNRVIGSGCNLDSARFR-----YLM------GERLGVHPL 182 Query: 178 HRKVTVIGGHSGETIIPI--------ITDKSLVFQL----DKQYEHFIHR-VQFGGDEIV 224 V+G H G++ +P+ ++ KSL QL DK+ +H+ V E++ Sbjct: 183 SCHGWVLGEH-GDSSVPVWSGVNVAGVSLKSLNPQLGTDADKEQWKDVHKQVVDSAYEVI 241 Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKP 257 K K G + ++ + A AE ++++ P Sbjct: 242 KLK---GYTSWAIGLSVADLAESIMKNLRRVHP 271 >1Y6J-A nrPDB Length = 318 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 75/259 (28%), Positives = 116/259 (44%), Gaps = 25/259 (9%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG----YD 58 KVAI+GA G VG + + L +EL L D+ + IG+ + IN +G Y Sbjct: 9 KVAIIGA-GFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMD-INHGLPFMGQMSLYA 66 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 D + + + V+++ AG RKPG TR DL K N I K + + K+ + ILV+SN Sbjct: 67 GDY--SDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSN 124 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQEQ 172 PV+ I ++K G V+G T LD +R +E VD + IG+ Sbjct: 125 PVD----IITYMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNVHGYIIGEHG 180 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232 D T I +G+ I I D F ++ + V+ G I+K K G+ Sbjct: 181 DSQLPLWSCTHI---AGKNINEYIDDPKCNFT-EEDKKKIAEDVKTAGATIIKNK---GA 233 Query: 233 ATLSMAFAGAKFAEEVLRS 251 +A + E +L++ Sbjct: 234 TYYGIAVSINTIVETLLKN 252 >1V6A-A nrPDB Length = 332 Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust. Identities = 84/324 (25%), Positives = 147/324 (45%), Gaps = 58/324 (17%) Query: 17 LSLLLKLSPYVSELALYDIRA--AEGIGKDLSH--INTNSSCVGYDKDSIENTLSNAQVV 72 +S+LLK ELAL D+ +G DL H + + + DKD + +N++VV Sbjct: 37 ISILLK--DLTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDY--SVTANSKVV 92 Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132 ++ AG ++ G +R +L + N I K ++ + K++PN +LV+SNPV+ L +A Sbjct: 93 VVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVAW---- 148 Query: 133 KMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGET 191 K+ V+G TNLD R + L K+G + H VIG H G++ Sbjct: 149 KLSGLPRNRVIGSGTNLDSAR-------FRHLMGEKLGIH--PSNCHG--WVIGEH-GDS 196 Query: 192 IIPIITDKSL--VF----------QLDKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMA 238 +P+ + ++ VF DK+ +H+ V E++K K G + ++ Sbjct: 197 SVPVWSGVNVAGVFLQGLNPDMGTDKDKEDWKSVHKMVVDSAYEVIKLK---GYTSWAIG 253 Query: 239 FAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNG 298 + A + +L++ P +S V + + G N + S+P +L N Sbjct: 254 MSAADLCQSILKNLRKCHP----VSTLV-----------KGMHGVNEEVFLSVPCILGNS 298 Query: 299 SVVSIDTSVLEKLSPREEQLVNTA 322 + + L+ S E+QLV +A Sbjct: 299 GLTDVVHMTLK--SDEEKQLVKSA 320 >4LN1-A nrPDB Length = 336 Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust. Identities = 89/342 (26%), Positives = 148/342 (43%), Gaps = 57/342 (16%) Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSH-INTNSSCVGYDKDSI 62 +L +G VG + + E L D+ A EG DLSH + + K S Sbjct: 31 VLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWKGSY 90 Query: 63 ENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNS 122 E+ +A +V+I AG+P+KPG TR DL + NA I K +V ++ + L+ +NPV+ Sbjct: 91 EDC-KDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPVDI 149 Query: 123 LVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVT 182 L + T K+ G K + T LD R L +Y IG H Sbjct: 150 LTYV---TWKESGLPKERVIGSGTTLDSARFRYMLGEYF-----DIGP-------HNIHA 194 Query: 183 VIGGHSGETIIPIITDKSL-------VFQLDKQYEH------FIHRVQFGGDEIVKAKQG 229 I G G+T +P+ + S+ + + D Y FI+ V+ I++ ++G Sbjct: 195 YIIGEHGDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFIN-VRDAAYHIIE-RKG 252 Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYF 289 A + M+ V ++ N++ ++SA++ G+ Q+ V Y Sbjct: 253 ATYYGIGMSLL------RVTKAILNDENSVLTVSAYL------EGQYGQKDV------YI 294 Query: 290 SLPIVLRNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRKNI 330 +P VL G V +LE +LS EE + +V+ L++ + Sbjct: 295 GVPAVLNRGGV----REILEVELSEDEELKFDHSVQVLKETM 332 >2V6B-A nrPDB Length = 304 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 49/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%) Query: 18 SLLLKLSPYVSELALYDIRA--AEGIGKDLSHIN--TNSSCVGYDKDSIENTLSNAQVVL 73 + L L SEL L D A+ +D++H ++ + V + S L++AQVV+ Sbjct: 16 AFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVWHGGHS---ELADAQVVI 72 Query: 74 IPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKK 133 + AG +KPG +R DL + NA I + LV + + AP+A +LV SNPV+ L +A + Sbjct: 73 LTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVDLLTDLATQLAPG 132 Query: 134 MGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGG 186 G V+ + A+ VD +G+ D + ++ G Sbjct: 133 QPVIGSGTVLDSARFRHLMAQHAGVDGTHAHGYVLGEHGDSEVLAWSSAMVAG 185 >4ND4-A nrPDB Length = 321 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 32/208 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI--GK--DLSH----INTNSSC 54 K+A++G SG +G ++ ++ ++++ L+DI AEGI GK D++H + S Sbjct: 6 KIAVIG-SGQIGGNIAYIVG-KDNLADVVLFDI--AEGIPQGKALDITHSMVMFGSTSKV 61 Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 +G + + +S + VV+I A +P +P R +L NA I+ S+ V K+ PNA ++ Sbjct: 62 IGTNDYA---DISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKYCPNAFVI 118 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173 I+NP++ + V +K+ V G+ LD R TF+ + + + Sbjct: 119 CITNPLD----VMVSHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQHFGVNASDV----- 169 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSL 201 VIGGH G+ ++P + S+ Sbjct: 170 ------SANVIGGH-GDGMVPATSSVSV 190 >1LDM-A nrPDB Length = 329 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 87/351 (24%), Positives = 154/351 (43%), Gaps = 60/351 (17%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56 K+ ++G G VG ++ + + E+AL D+ + G+ DL H ++T G Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG 80 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 D + + +++V+I AG ++ G +R +L + N I K ++ + K +P+ ILV+ Sbjct: 81 KD----YSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVV 136 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKT 175 SNPV+ L +A K+ ++G NLD R YLM G+ Sbjct: 137 SNPVDVLTYVAW----KLSGLPMHRIIGSGCNLDSARFR-----YLM------GERLGVH 181 Query: 176 TMHRKVTVIGGHSGETIIPIITDKSLV---------FQLDKQYEHFIHR-VQFGGDEIVK 225 + VIG H G+++ + + ++ DKQ +H+ V E++K Sbjct: 182 SCSCHGWVIGEH-GDSVPSVWSGMNVASIKLHPLDGTNKDKQDWKKLHKDVVDSAYEVIK 240 Query: 226 AKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNS 285 K G + ++ + A AE ++++ P + + F G+K DN Sbjct: 241 LK---GYTSWAIGLSVADLAETIMKNLCRVHPVSTMVKDFY---GIK----------DNV 284 Query: 286 IEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 + SLP VL + + +I V KL P EEQ + + L +I+K F Sbjct: 285 --FLSLPCVLNDHGISNI---VKMKLKPNEEQQLQKSATTLW-DIQKDLKF 329 >1LTH-T nrPDB Length = 319 Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 74/273 (27%), Positives = 115/273 (42%), Gaps = 23/273 (8%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60 K+A++GA G VG L+ E+ L DI E D+ H ++ V D Sbjct: 9 KLAVIGA-GAVGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGS 67 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 +A +V+I AG +KPG +R +L I+K+++ + K APNA ++I+NPV Sbjct: 68 DDPEICRDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPV 127 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPK------IGQEQD 173 + IA +K+ + G TNLD R FL+ N K G+ D Sbjct: 128 D----IATHVAQKLTGLPENQIFGSGTNLDSARLR-FLIAQQTGVNVKNVHAYIAGEHGD 182 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGS 232 + IGG P+ L DK+ E IH+ V+ +I+ K G+ Sbjct: 183 SEVPLWESATIGGVPMSDWTPLPGHDPL--DADKREE--IHQEVKNAAYKIINGK---GA 235 Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAF 265 ++ +G E VL + P + L F Sbjct: 236 TNYAIGMSGVDIIEAVLHDTNRILPVSSMLKDF 268 >4Q3N-A nrPDB Length = 314 Score = 57.8 bits (138), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 89/321 (27%), Positives = 134/321 (41%), Gaps = 54/321 (16%) Query: 27 VSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKDSIE----NTLSNAQVVLIPAGVPR 80 V EL L DI R AEG DL+H G K SI+ +A +V+I AGV + Sbjct: 28 VEELVLLDIDKRKAEGEAMDLNH----GLAFGPRKMSIKAGDYKDCKDAGLVVITAGVNQ 83 Query: 81 KPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPG 140 K G TR L K NA I+K++V + N +LV SNPV+ L +A K+ G Sbjct: 84 KEGETRIHLLKRNAEIIKTVVKNIMSSGFNGILLVASNPVDVLAYVA---WKESGLHHSR 140 Query: 141 NVMGVTNLDLVRAETFLVDYLMLKNPKI-----GQEQDKTTMHRKVTVIGGHSGETIIPI 195 + T+LD R + Y+ + + + G+ D + +G +I Sbjct: 141 VIGSGTSLDTARLRYEISQYIHIDSRNVHAYILGEHGDSEFVCWSNANVGAKPIADVIDS 200 Query: 196 ITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ----GAGSATLSMAFAGAKFAEEVLRS 251 + + S + EH +V+ EI+ K+ G G A + + A Sbjct: 201 MDEISF-----EDLEHIYLKVRDAAYEIISRKKATYYGIGMALVRITAA----------I 245 Query: 252 FHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE-YFSLPIVLRNGSVVSIDTSVLEK 310 F+NE + + + L NG V D + Y LP VL V I V K Sbjct: 246 FNNE-------NRILPISVLNNG------VYDCEDQVYIGLPAVLNKDGVHHI---VKLK 289 Query: 311 LSPREEQLVNTAVKELRKNIE 331 L+ +E +N + LRKN++ Sbjct: 290 LNEKENSQLNNSANILRKNLD 310 >4I1I-A nrPDB Length = 345 Score = 57.8 bits (138), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 50/253 (19%) Query: 2 VKVAILGASGGVGQPLSLLLK----LSPYVS-ELALYDI----RAAEGIGKDLSH----- 47 VKVA+ GA+G +G L L+ L P EL L DI +A G+ +L Sbjct: 25 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 84 Query: 48 ----INTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTA 103 + T V +D + ++ PRK G+ R DL +MNA I K A Sbjct: 85 LDKVVVTADPRVAFD---------GVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEA 135 Query: 104 VGKFAP-NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLM 162 + A + R++V+ NP N+ I +++ + GK P +V +T LD RA + L Sbjct: 136 IAAVAASDCRVVVVGNPANTNALILLKSAQ--GKLNPRHVTAMTRLDHNRALSLLARKAG 193 Query: 163 LKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLV--------FQLDKQYEHFIH 214 + ++ R V + G HS T +P TD +++ + D + F+ Sbjct: 194 VPVSQV----------RNVIIWGNHS-STQVP-DTDSAVIGTTPAREAIKDDALDDDFVQ 241 Query: 215 RVQFGGDEIVKAK 227 V+ G EI++ + Sbjct: 242 VVRGRGAEIIQLR 254 >5K0Z-A nrPDB Length = 331 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 76/315 (24%), Positives = 137/315 (43%), Gaps = 47/315 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYD 58 K+ ++G G VG ++ + ELAL D+ + G+ DL H + + + D Sbjct: 21 KITVVGV-GQVGMACAISILGKGLCDELALVDVLEDKLKGEMMDLQHGSLFLQTHKIVAD 79 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 KD +N+++V++ AGV ++ G +R +L + N + K ++ + K++PN ILV+SN Sbjct: 80 KDYA--VTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPNCTILVVSN 137 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPK-----IGQEQD 173 PV+ L + T K G K + NLD R + + L + +G+ D Sbjct: 138 PVDILTYV---TWKLSGLPKHRVIGSGCNLDTARFRYLMAERLGIHPTSCHGWILGEHGD 194 Query: 174 KTTMHRKVTVIGGHSGETIIPII-TDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAG 231 + + G S + + P + TDK D + +H+ V E+++ K G Sbjct: 195 SSVAVWSGVNVAGVSLQELNPAMGTDK------DSENWKEVHKQVVESAYEVIRLK---G 245 Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE---Y 288 ++ + A+ E +L++ + S+S V G IE + Sbjct: 246 YTNWAIGLSVAELCETMLKNLY----RVHSVSTLVK--------------GTYGIENDVF 287 Query: 289 FSLPIVLRNGSVVSI 303 SLP VL + S+ Sbjct: 288 LSLPCVLSASGLTSV 302 >1CIV-A nrPDB Length = 385 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 29/214 (13%) Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARILVISNPVNSLV 124 +A+ L+ PR PG+ R DL +N I A+ A PN +++V+ NP N+ Sbjct: 116 FQDAEWALLIGAKPRGPGMERADLLDINGQIFAEQGKALNAVASPNVKVMVVGNPCNT-- 173 Query: 125 PIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI 184 A+ LK P N +T LD RA+ L K G DK + VT+ Sbjct: 174 -NALICLKNAPNIPPKNFHALTRLDENRAKCQLA-------LKAGVFYDKVS---NVTIW 222 Query: 185 GGHSGETIIPIITDK------SLVFQLDKQY--EHFIHRVQFGGDEIVKAKQGAGSATLS 236 G HS + + K + V + D+++ + F + VQ G ++K + +A+ + Sbjct: 223 GNHSTTQVPDFLNAKIHGIPVTEVIR-DRKWLEDEFTNMVQTRGGVLIKKWGRSSAASTA 281 Query: 237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPG 270 ++ A +RS PE + S VY G Sbjct: 282 VSIVDA------IRSLVTPTPEGDWFSTGVYTNG 309 >6IHE-A nrPDB Length = 303 Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 42/138 (30%), Positives = 73/138 (52%), Gaps = 10/138 (7%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHI----NTNSSCVG 56 KV +GA G +GQ ++ +S V E +YDI + +L H ++ +G Sbjct: 2 KVGFIGA-GKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFATKGIKANVLG 60 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 +S+++ +S +V+I AG PRKPG++R DLF NA I+ L + P A L++ Sbjct: 61 --TNSLDD-VSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKLPSKNPGAIYLMV 117 Query: 117 SNPVNSLVPIAVETLKKM 134 +NPV+ + + ++ K+ Sbjct: 118 ANPVDMMASVFMKYSKQF 135 >4M1Q-A nrPDB Length = 339 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 58/198 (29%), Positives = 86/198 (43%), Gaps = 21/198 (10%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH-INTNSSCVGYDK 59 +V I+G +G VG + + E+ L D+ R EG DL+H I + + Sbjct: 29 RVVIIG-TGAVGSSYAFSMINQNVTDEMVLIDLDKRKTEGDAMDLNHGIPFGAPTKVWAG 87 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 D +A +V+I AG +KPG TR DL + NA I K +V V N ++ +NP Sbjct: 88 DY--GDCKSADIVVITAGAAQKPGETRLDLVEKNANIFKGIVDQVMGSGFNGIFIIATNP 145 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 V+ L A T K G K + T LD R L +Y + D +H Sbjct: 146 VDVL---AYATWKFSGLPKERVIGSGTILDTARFRFLLSEYF---------DIDVRNIH- 192 Query: 180 KVTVIGGHSGETIIPIIT 197 I G G+T +P+ + Sbjct: 193 --GYIMGEHGDTELPVWS 208 >2D4A-B nrPDB Length = 308 Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 46/161 (28%), Positives = 83/161 (51%), Gaps = 16/161 (9%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRA-AEGIGKDLSHINTNSSCVGYD---- 58 + ILGA G VG +++L + Y L + +G DL+H ++ +G D Sbjct: 2 ITILGA-GKVGMATAVMLMMRGYDDLLLIARTPGKPQGEALDLAH---AAAELGVDIRIS 57 Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 +S E+ + + +VL+ AG+ RKPG+TR+ L + NA + L + +A +A +++ + Sbjct: 58 GSNSYED-MRGSDIVLVTAGIGRKPGMTREQLLEANANTMADLAEKIKAYAKDAIVVITT 116 Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFL 157 NPV+++ + KK G F V+G + LD R ++ Sbjct: 117 NPVDAMTYV---MYKKTG-FPRERVIGFSGILDSARMAYYI 153 >4KDE-A nrPDB Length = 341 Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 59/205 (28%), Positives = 88/205 (42%), Gaps = 28/205 (13%) Query: 2 VKVAILGASGGVGQPL-------SLLLKLSPYVSELALYDI----RAAEGIGKDLSHINT 50 V+VA+ GA+G +G L +L K P + L L +I +A EG+ +L Sbjct: 5 VRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVI--LQLLEIPQAMKALEGVVMELEDCAF 62 Query: 51 NSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-P 109 D + +A L+ PRK G+ R DL ++N I A+ + A Sbjct: 63 PLLAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKK 122 Query: 110 NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIG 169 + ++LV+ NP N+ IA K P N +T LD RA+ L K G Sbjct: 123 DVKVLVVGNPANTNALIA---YKNAPGLNPRNFTAMTRLDHNRAKAQLAK-------KTG 172 Query: 170 QEQDKTTMHRKVTVIGGHSGETIIP 194 D+ R++TV G HS T+ P Sbjct: 173 TGVDRI---RRMTVWGNHS-STMFP 193 >1T24-A nrPDB Length = 322 Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 41/127 (32%), Positives = 65/127 (51%), Gaps = 9/127 (7%) Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIENT 65 +L SG +G ++ L+ + + ++ L+DI GK L +TN K S NT Sbjct: 8 VLVGSGMIGGVMATLI-VQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNT 66 Query: 66 ---LSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 L+ A VV++ AG + PG RDDL +N I+ + + K PNA I+V++ Sbjct: 67 YDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVT 126 Query: 118 NPVNSLV 124 NPV+ +V Sbjct: 127 NPVDVMV 133 >6CEP-A nrPDB Length = 334 Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 45/163 (27%), Positives = 83/163 (50%), Gaps = 10/163 (6%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYD 58 K+ ++G G VG ++ + ELAL D+ + G+ DL H + + + D Sbjct: 23 KITVVGV-GQVGMACAISILGKSLTDELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 KD + +N+++V++ AGV ++ G +R +L + N + K ++ + K++P+ I+V+SN Sbjct: 82 KDY--SVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSN 139 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYL 161 PV+ L + T K G K + NLD R + + L Sbjct: 140 PVDILTYV---TWKLSGLPKHRVIGSGCNLDSARFRYLMAEKL 179 >5NUE-A nrPDB Length = 332 Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 71/277 (25%), Positives = 117/277 (42%), Gaps = 39/277 (14%) Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARILVISN 118 D++E + V ++ G PRK G+ R D+ N I KS A+ K A PN ++LV++N Sbjct: 74 DAVEGC-TGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVAN 132 Query: 119 PVNSLVPIAVETLKKMGKFKP-GNVMGVTNLDLVRA-----ETFLVDYLMLKNPKI---- 168 P N+ I LK+ P N+ +T LD RA E V +KN I Sbjct: 133 PANTNALI----LKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNH 188 Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228 Q H KV G + + ++ D + LD + FI VQ G I+KA++ Sbjct: 189 SSSQYPDVNHAKVQTSSGE--KPVRELVKDDAW---LDGE---FISTVQQRGAAIIKARK 240 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 + + + + + + +R + PE +S VY G + Sbjct: 241 LSSALSAASSAC------DHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGL---------I 285 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKE 325 +S P+ RNG + ++++S ++ L +KE Sbjct: 286 YSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKE 322 >3D0O-A nrPDB Length = 317 Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 82/310 (26%), Positives = 123/310 (39%), Gaps = 49/310 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVGYDKD 60 KV ++G +G VG + L V EL + D+ + G DL H S K Sbjct: 8 KVVLIG-NGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKA 66 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + +A +V+I AG +KPG TR DL N I KS+V V + LV +NPV Sbjct: 67 GEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPV 126 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 + L A T K G K + T LD R L + D Sbjct: 127 DIL---AYATWKFSGLPKERVIGSGTILDSARFRLLLSEAF-----------DVAPRSVD 172 Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDK-----------QYEHFIHRVQFGGDEIVKAKQG 229 +IG H G+T +P+ + ++ Q K Q E + + +I++AK Sbjct: 173 AQIIGEH-GDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAK-- 229 Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYF 289 G+ +A A+ E + F NE A + + L G+ ++ V Y Sbjct: 230 -GATYYGVAMGLARITEAI---FRNE-------DAVLTVSALLEGEYEEEDV------YI 272 Query: 290 SLPIVL-RNG 298 +P V+ RNG Sbjct: 273 GVPAVINRNG 282 >5HTO-A nrPDB Length = 346 Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 38/133 (28%), Positives = 68/133 (51%), Gaps = 11/133 (8%) Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHIN--TNSSCVGYDKDS 61 +L SG +G ++ L+ + + ++ ++D+ +G D SH N S+C +S Sbjct: 38 VLVGSGMIGGVMATLI-VQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNS 96 Query: 62 IENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 ++ L A VV++ AG + PG RDDL +N I+ + + PNA I+V+ Sbjct: 97 YDD-LKGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVV 155 Query: 117 SNPVNSLVPIAVE 129 +NPV+ +V + E Sbjct: 156 TNPVDVMVQLLFE 168 >3PQF-A nrPDB Length = 326 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 84/334 (25%), Positives = 135/334 (40%), Gaps = 51/334 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVGYDKD 60 KVA++GA G VG + L EL + D+ + +G DL+H + Sbjct: 7 KVALIGA-GFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLNHGKAFAPQPVKTSY 65 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 +A +V I AG +KPG TR +L + N I K +V+ V + LV +NPV Sbjct: 66 GTYEDCKDADIVCICAGANQKPGETRLELVEKNLKIFKGIVSEVMASGFDGIFLVATNPV 125 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 + L T K G K + T LD R L +Y G H Sbjct: 126 DILT---YATWKFSGLPKERVIGSGTTLDSARFRFMLSEYF-------GAAPQNVCAH-- 173 Query: 181 VTVIGGHSGETIIPIITDKS--------LVFQLD----KQYEHFIHRVQFGGDEIVKAKQ 228 +IG H G+T +P+ + + LV + D ++ + + V+ I++ K Sbjct: 174 --IIGEH-GDTELPVWSHANVGGVPVSELVEKNDAYKQEELDQIVDDVKNAAYHIIEKK- 229 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 G+ +A + A+ + +L HN E L+ YL G Q D+ Y Sbjct: 230 --GATYYGVAMSLARITKAIL---HN---ENSILTVSTYLDG--------QYGADDV--Y 271 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTA 322 +P V+ G + I L + +EQ +++A Sbjct: 272 IGVPAVVNRGGIAGITELNLNE--KEKEQFLHSA 303 >1OC4-A nrPDB Length = 322 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 9/127 (7%) Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIENT 65 +L SG +G ++ L+ + + ++ ++DI GK L +TN K S NT Sbjct: 8 VLVGSGMIGGVMATLI-VQKNLGDVVMFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNT 66 Query: 66 ---LSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 L +A VV++ AG + PG RDDL +N I+ + + PNA I+V++ Sbjct: 67 YDDLKDADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNNCPNAFIIVVT 126 Query: 118 NPVNSLV 124 NPV+ +V Sbjct: 127 NPVDVMV 133 >5MDH-A nrPDB Length = 333 Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 72/296 (24%), Positives = 125/296 (42%), Gaps = 46/296 (15%) Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA-RI 113 + DK+ I + V ++ +PR+ G+ R DL K N I K A+ K+A + ++ Sbjct: 68 IATDKEEI--AFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSVKV 125 Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQD 173 +V+ NP N+ A ++ + K N +T LD RA+ + K+G D Sbjct: 126 IVVGNPANTNCLTASKSAPSIPK---ENFSCLTRLDHNRAKAQIA-------LKLGVTSD 175 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDK--QYE----------HFIHRVQFGGD 221 + V + G HS T P + + Q + YE FI VQ G Sbjct: 176 DV---KNVIIWGNHSS-TQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQRGA 231 Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281 ++KA++ LS A + AK + +R PE E +S + G G V Sbjct: 232 AVIKARK------LSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYG------V 279 Query: 282 GDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 D+ + +S P+ +++ + ++ + S RE+ ++ KEL + E F+ Sbjct: 280 PDDLL--YSFPVTIKDKTWKIVEGLPINDFS-REK--MDLTAKELAEEKETAFEFL 330 >4UUO-A nrPDB Length = 340 Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 52/210 (24%), Positives = 85/210 (40%), Gaps = 25/210 (11%) Query: 2 VKVAILGASGGVGQPLSLLL---------KLSPYVSELALYDIRAAEGIGKDLSHINTNS 52 + + I GA+G +G L+ + K+ ++ E+ + ++A EG +L + Sbjct: 4 IHILITGAAGQIGYALTFRIAKGDLCGDRKVVLHLLEIP-FGMKALEGCVMELQDCAFPN 62 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNA 111 D +E V + PRK G+ R DL N GI A+ +A P Sbjct: 63 VAGIVWTDKVEEAFKGVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALNDYAKPTV 122 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171 ++LV+ NP N+ IA + K+ + N +T LD R L + KI Sbjct: 123 KVLVVGNPANTNCLIAQASAPKL---QNKNWCAMTRLDHNRMVGALAAKFGVTPEKI--- 176 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSL 201 KV + G HS T +P T ++ Sbjct: 177 -------HKVCIWGNHS-NTQVPDTTHATV 198 >3WSV-A nrPDB Length = 322 Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 58/193 (30%), Positives = 85/193 (44%), Gaps = 15/193 (7%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDL-SHINTNSSCVGYDK 59 KV I+G +G VG ++ + +EL L D+ AEG DL + V Sbjct: 7 KVVIVG-TGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNVSVWS 65 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + E +A +V++ AGV +KPG TR DL K NA I + +V V + +V SNP Sbjct: 66 GTYEE-CQDANLVILTAGVNQKPGQTRLDLVKTNATITRQIVKEVMASGFDGIFVVASNP 124 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQEQD 173 V+ L + T ++ G V+G T LD R A VD + +G+ D Sbjct: 125 VDILTYL---TWQESG-LPASRVVGTGTTLDTTRFRKEIALKLAVDPRSVHGYILGEHGD 180 Query: 174 KTTMHRKVTVIGG 186 T +GG Sbjct: 181 SEVAAWSHTTVGG 193 >6J9S-A nrPDB Length = 326 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 74/277 (26%), Positives = 116/277 (41%), Gaps = 57/277 (20%) Query: 68 NAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIA 127 +A +V+I AG P+KPG TR DL N I+KS+V + N LV +NPV+ I Sbjct: 76 DADLVVITAGAPQKPGETRLDLVNKNLKILKSIVDPIVDSGFNGIFLVAANPVD----IL 131 Query: 128 VETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGG 186 K+ F V+G T+LD R + + + D ++H I G Sbjct: 132 TYATWKLSGFPKNRVVGSGTSLDTARFRQSIAKMVNV---------DARSVH---AYIMG 179 Query: 187 HSGETIIPIITDKSL-------------VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233 G+T P+ + ++ + DK + F V+ EI+K K G+ Sbjct: 180 EHGDTEFPVWSHANIGGVTIAEWVKAHPEIKEDKLVKMF-EDVRNKAYEIIKLK---GAT 235 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 +A A A+ ++ +L E L VY+ G G N I Y P Sbjct: 236 FYGIATALARISKAILND------ENAVLPLSVYMDG---------QYGLNDI-YIGTPA 279 Query: 294 VL-RNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRK 328 V+ RNG ++LE L+ EE+ + + +L+K Sbjct: 280 VINRNGI-----QNILEIPLTDHEEESMQKSASQLKK 311 >4BGU-A nrPDB Length = 303 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%) Query: 21 LKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI------ENTLSNAQVVLI 74 L L EL DI E K + + + YD +++ E+T + + VV+I Sbjct: 20 LALRDVCDELVFVDIPKMED--KTVGQAADTNHGIAYDSNTVVTQGGYEDT-AGSDVVVI 76 Query: 75 PAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSL 123 AG+PR+PG TR DL NA I+ + +++ ++ + + SNPV+ L Sbjct: 77 TAGIPRQPGQTRIDLAGDNAPIMDDIGSSLAEYNDDFVSITTSNPVDLL 125 >7MDH-A nrPDB Length = 375 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 66/269 (24%), Positives = 107/269 (39%), Gaps = 43/269 (15%) Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NARILVISNPVNSLV 124 + L+ PR PG+ R L +N I A+ A N ++LV+ NP N+ Sbjct: 106 FEDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASKNVKVLVVGNPCNT-- 163 Query: 125 PIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI 184 A+ LK N +T LD RA+ L K G DK + VT+ Sbjct: 164 -NALICLKNAPDIPAKNFHALTRLDENRAKCQLA-------LKAGVFYDKVS---NVTIW 212 Query: 185 GGHSGETIIPIITD--------KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLS 236 G HS T +P + K ++ + E F VQ G +++ + +A+ + Sbjct: 213 GNHS-TTQVPDFLNAKIDGRPVKEVIKRTKWLEEEFTITVQKRGGALIQKWGRSSAASTA 271 Query: 237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLR 296 ++ A A ++S PE + S VY G G A+ +V FS+P + Sbjct: 272 VSIADA------IKSLVTPTPEGDWFSTGVYTTGNPYG-IAEDIV-------FSMPCRSK 317 Query: 297 N------GSVVSIDTSVLEKLSPREEQLV 319 + VS D + E++ E +L+ Sbjct: 318 GDGDYELATDVSNDDFLWERIKKSEAELL 346 >4UUM-A nrPDB Length = 341 Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 4/89 (4%) Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARILVISNPVNSLV 124 + + A +P KPG R DL N+ I K+ + K+A P+ ++LVI NP N+ Sbjct: 77 FKDIDCAFLVASMPLKPGQVRADLISSNSVIFKNTGEYLSKWAKPSVKVLVIGNPDNTNC 136 Query: 125 PIAVETLKKMGKFKPGNVMGVTNLDLVRA 153 IA+ K + KP N ++ LD RA Sbjct: 137 EIAMLHAKNL---KPENFSSLSMLDQNRA 162 >4JCO-A nrPDB Length = 304 Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 6/75 (8%) Query: 49 NTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA 108 NT GY E+T + + VV+I AG+PR+PG TR DL NA I++ + +++ + Sbjct: 58 NTRVRQGGY-----EDT-AGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHN 111 Query: 109 PNARILVISNPVNSL 123 + L SNPV+ L Sbjct: 112 DDYISLTTSNPVDLL 126 >2LDB-A nrPDB Length = 317 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 82/327 (25%), Positives = 127/327 (38%), Gaps = 56/327 (17%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYD 58 +V ++GA G VG L E+ L D ++ IG D +H + + Sbjct: 8 RVVVIGA-GFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPVDIWH 66 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 D + +A +V+I AG +KPG TR DL N I +S+V +V LV +N Sbjct: 67 GDY--DDCRDADLVVICAGANQKPGETRLDLVDKNIAIFRSIVESVMASGFQGLFLVATN 124 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMH 178 PV+ L T K G + T LD R L +Y + + Sbjct: 125 PVDILT---YATWKFSGLPHERVIGSGTILDTARFRFLLGEYFSVAPQNV---------- 171 Query: 179 RKVTVIGGHSGETIIPIITD--------KSLV----FQLDKQYEHFIHRVQFGGDEIVKA 226 +IG H G+T +P+ + + LV + K E V+ +I++ Sbjct: 172 -HAYIIGEH-GDTELPVWSQAYIGVMPIRKLVESKGEEAQKDLERIFVNVRDAAYQIIEK 229 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286 K G+ +A A+ +L HNE L+ YL GL + Sbjct: 230 K---GATYYGIAMGLARVTRAIL---HNENA---ILTVSAYLDGLYGERDV--------- 271 Query: 287 EYFSLPIVL-RNG--SVVSIDTSVLEK 310 Y +P V+ RNG V+ I+ + EK Sbjct: 272 -YIGVPAVINRNGIREVIEIELNDDEK 297 >1EZ4-A nrPDB Length = 318 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 23/56 (41%), Positives = 33/56 (58%) Query: 68 NAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSL 123 +A +V+I AG P+KPG +R DL N I+ S+V V + LV +NPV+ L Sbjct: 72 DADLVVITAGAPQKPGESRLDLVNKNLNILSSIVKPVVDSGFDGIFLVAANPVDIL 127 >1B8U-A nrPDB Length = 329 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 1/66 (1%) Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NARILVISNPVNSLV 124 +A V L+ PR PG+ R DL + NA I A+ A N ++LV+ NP N+ Sbjct: 81 FKDADVALLVGARPRGPGMERKDLLEANAQIFTVQGKAIDAVASRNIKVLVVGNPANTNA 140 Query: 125 PIAVET 130 IA+++ Sbjct: 141 YIAMKS 146 >3DL2-A nrPDB Length = 303 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 61/249 (24%), Positives = 109/249 (43%), Gaps = 47/249 (18%) Query: 88 DLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGV-T 146 D+ + N + ++LV A+G ++ ++ +LV S PV + + K+ F V+G+ Sbjct: 96 DVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVT----WKLSTFPANRVIGIGC 151 Query: 147 NLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLD 206 NLD R + + + +LK G+E V VI G GE DK L + Sbjct: 152 NLDSQRLQYIITN--VLKAQTSGKE---------VWVI-GEQGE-------DKVLTWSGQ 192 Query: 207 KQYEHFIHRVQFGGD--EIVKAK-QGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLS 263 ++ +VQ E+++ K Q + S LS+A +++ S N K + S+S Sbjct: 193 EEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVA--------DMVDSIVNNKKKVHSVS 244 Query: 264 AFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTA 322 A A+ NS + SLP +L NG I T++ E + Q ++ Sbjct: 245 AL-----------AKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASS 293 Query: 323 VKELRKNIE 331 + L++ ++ Sbjct: 294 IHSLQQQLK 302 >3D5T-A nrPDB Length = 331 Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust. Identities = 46/182 (25%), Positives = 73/182 (40%), Gaps = 33/182 (18%) Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NARILVISN 118 D + +A V L+ PR G+ R DL NA I A+ + A + ++LV+ N Sbjct: 77 DDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGAALNEVASRDVKVLVVGN 136 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMH 178 P N+ IA+++ + K N + LD RA + L + Sbjct: 137 PANTNAYIAMKSAPDLPK---KNFTAMLRLDHNRALSQLA----------AKSGKPVASI 183 Query: 179 RKVTVIGGHS-------------GETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVK 225 K+ V G HS GE+++ +I D V+ D FI V G I++ Sbjct: 184 EKLAVWGNHSPTMYPDFRFATAEGESLLKLINDD--VWNRDT----FIPTVGKRGAAIIE 237 Query: 226 AK 227 A+ Sbjct: 238 AR 239 >4TVO-A nrPDB Length = 330 Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust. Identities = 65/260 (25%), Positives = 103/260 (39%), Gaps = 64/260 (24%) Query: 2 VKVAILGASGGVGQPLSLLLKLS---------PYVSELALYDI----RAAEGIGKDLSHI 48 +KVA+ GA+G +G SLL +L+ P EL L +I +A EG+ +L Sbjct: 6 LKVAVTGAAGQIG--YSLLFRLASGSLLGPDRPI--ELRLLEIEPALQALEGVVMELDDC 61 Query: 49 N---TNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVG 105 + +G D I + +S + L+ PR G+ R DL + N I + A+ Sbjct: 62 AFPLLSGVEIGSDPQKIFDGVS---LALLVGARPRGAGMERSDLLEANGAIFTAQGKALN 118 Query: 106 KFAP-NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLK 164 A + R+ V NP N+ IA +TN + E F + Sbjct: 119 AVAADDVRVGVTGNPANTNALIA-----------------MTNAPDIPRERFSALTRLDH 161 Query: 165 NPKIGQEQDKT----TMHRKVTVIGGHS-------------GETIIPIITDKSLVFQLDK 207 N I Q KT T +K+T+ G HS G+ ++ D++ + Sbjct: 162 NRAISQLAAKTGAAVTDIKKMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWI----- 216 Query: 208 QYEHFIHRVQFGGDEIVKAK 227 + FI V G I+ A+ Sbjct: 217 -EDEFIPTVAKRGAAIIDAR 235 >5ZF1-A nrPDB Length = 301 Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 18/98 (18%) Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD-KDSIEN 64 ++G S VG P++++L D R G+G D T + C Y KD +E Sbjct: 163 VIGRSKNVGMPIAMMLH----------SDKRHESGLGMDA----TVTICHRYTPKDKLEA 208 Query: 65 TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT 102 NA +++ G+P+ L + D+ K A I+ +T Sbjct: 209 YCRNADIIITATGLPK---LIKADMVKPGATIIDVGIT 243 >4ARE-A nrPDB Length = 695 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 10/91 (10%) Query: 68 NAQVVLIPA--GVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVP 125 N Q IPA + + P FK+ + ++T++GK NA + VN+ VP Sbjct: 118 NFQDKCIPAMIAIQKNPN------FKLGTAVQDEVITSLGKLIGNAS--ANAEVVNNCVP 169 Query: 126 IAVETLKKMGKFKPGNVMGVTNLDLVRAETF 156 + + + + ++ P V G +L++ F Sbjct: 170 VLKQFRENLNQYAPDYVKGTAVNELIKGIEF 200 >2Y6I-A nrPDB Length = 785 Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 10/91 (10%) Query: 68 NAQVVLIPA--GVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVP 125 N Q IPA + + P FK+ + ++T++GK NA + VN+ VP Sbjct: 118 NFQDKCIPAMIAIQKNPN------FKLGTAVQDEVITSLGKLIGNAS--ANAEVVNNCVP 169 Query: 126 IAVETLKKMGKFKPGNVMGVTNLDLVRAETF 156 + + + + ++ P V G +L++ F Sbjct: 170 VLKQFRENLNQYAPDYVKGTAVNELIKGIEF 200 >6H1E-A nrPDB Length = 208 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 6/91 (6%) Query: 192 IIPIITD--KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVL 249 I P+ITD K L+ +L ++ + + F +V Q GS + A+AG + EV+ Sbjct: 91 IQPVITDLVKGLLPRLTEKVDLLV----FNPPYVVTPPQEVGSHGIEAAWAGGRNGREVM 146 Query: 250 RSFHNEKPETESLSAFVYLPGLKNGKKAQQL 280 F P+ S YL +K + L Sbjct: 147 DRFFPLVPDLLSPRGLFYLVTIKENNPEEIL 177 >3QB0-A nrPDB Length = 498 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 11/89 (12%) Query: 218 FGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKA 277 +GGDE+ GS T ++ ++G+ F + +L S + + E + Sbjct: 18 YGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIF----------S 67 Query: 278 QQLVGDNSIEYFSLPIVLRNGSVVSIDTS 306 +Q +G +Y PI+ NG V+ DT+ Sbjct: 68 EQSIGIPRKDYELKPII-ENGLVIDWDTA 95 >6APE-A nrPDB Length = 298 Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust. Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 11/107 (10%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSS--CVGYDK-D 60 VAI+GAS +G+PLS+L+ L+ S + + KD+S N+ CVG K D Sbjct: 173 VAIIGASNIIGKPLSMLM-LNAGAS------VSVCHILTKDISFYTQNADIVCVGVGKPD 225 Query: 61 SIENTLSNAQVVLIPAGVPR-KPGLTRDDLFKMNAGIVKSLVTAVGK 106 I+ ++ V++ G+ G D+ NA V +T V K Sbjct: 226 LIKASMLKKGAVVVDIGINHLNDGRIVGDVDFTNAQKVAGFITPVPK 272 >5CEF-A nrPDB Length = 375 Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 19/31 (61%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL 32 +KV +LGA+G VGQ LL PY + AL Sbjct: 9 IKVGVLGATGTVGQRFIELLAAHPYFALHAL 39 >2NVK-X nrPDB Length = 488 Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 8/53 (15%) Query: 61 SIENTLSNAQVVLIPAGVPRKP--------GLTRDDLFKMNAGIVKSLVTAVG 105 S E T++ V+ G PR P G+T DDLF ++ K+LV G Sbjct: 144 SGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAG 196 >2BE7-D nrPDB Length = 153 Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 11/84 (13%) Query: 46 SHINTNSSCVGYDKDSIEN----------TLSNA-QVVLIPAGVPRKPGLTRDDLFKMNA 94 +H+ + C GY D I + +L++ Q V + +P K G +D + N Sbjct: 4 NHMQVEAICNGYVIDHIPSGQGVKILKLFSLTDTKQRVTVGFNLPTKDGNAKDLIKVENT 63 Query: 95 GIVKSLVTAVGKFAPNARILVISN 118 I KS + APNA I +I N Sbjct: 64 EITKSQANQLALLAPNATINIIEN 87 >4B9V-A nrPDB Length = 619 Score = 27.7 bits (60), Expect = 7.5, Method: Compositional matrix adjust. Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 2/100 (2%) Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPET-ESLSAFVY-LPGLKNGKKAQQL 280 +V+ +Q S M FAG K + L E E ++ +Y L G + + + Sbjct: 217 LVELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLRTVEQRIYELAGQEFNINSPKQ 276 Query: 281 VGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVN 320 +G E LP++ ++ + S VLEKL+P E + N Sbjct: 277 LGVILFEKLQLPVLKKSKTGYSTSADVLEKLAPYHEIVEN 316 >3EH7-A nrPDB Length = 434 Score = 27.7 bits (60), Expect = 7.6, Method: Compositional matrix adjust. Identities = 29/139 (20%), Positives = 57/139 (41%), Gaps = 7/139 (5%) Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAV-ETL 131 IP P + R D+ ++ IV+ + + S P + + E Sbjct: 101 FIPVFFYEVPSMIRKDILHIDVAIVQLSMPDENGYCSFGVSCDYSKPAAESAHLVIGEIN 160 Query: 132 KKMGKFKPGNVMGVTNLDLVRAETFLVDYLM--LKNPKIGQEQDKTTMHRKVTVIGGHSG 189 ++M N++ ++ LD + + DY + L PKIG+ ++ + + G + Sbjct: 161 RQMPYVHGDNLIHISKLDYI----VMADYPIYSLAKPKIGEVEEAIGRNCAELIEDGATL 216 Query: 190 ETIIPIITDKSLVFQLDKQ 208 + I I D +L+F DK+ Sbjct: 217 QLGIGAIPDAALLFLKDKK 235 >1RVY-A nrPDB Length = 483 Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust. Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 10/82 (12%) Query: 194 PIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAG-SATL---SMAFAGAKFAEEVL 249 P +T + L+ + ++ HFIHR G + V+ + G ATL AG + + + Sbjct: 405 PALTSRGLLEKDFQKVAHFIHR---GIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAV 461 Query: 250 RSFHNEKPETESLSAFVYLPGL 271 R+ + E ES +A LPGL Sbjct: 462 RAL---RQEVESFAALFPLPGL 480 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5ZI4-A nrPDB 395 e-110 1MLD-A nrPDB 278 2e-75 4E0B-A nrPDB 272 1e-73 4WLE-A nrPDB 272 2e-73 4L4S-H nrPDB 268 2e-72 5NQB-A nrPDB 268 3e-72 1IE3-A nrPDB 267 6e-72 4PLW-A nrPDB 267 7e-72 9LDB-A nrPDB 267 7e-72 1SMK-A nrPDB 266 1e-71 4AJN-A nrPDB 263 1e-70 6BAL-A nrPDB 261 4e-70 1LDM-A nrPDB 259 2e-69 4PLF-A nrPDB 255 2e-68 6CEP-A nrPDB 251 3e-67 4LN1-A nrPDB 250 6e-67 3PQF-A nrPDB 249 2e-66 5K0Z-A nrPDB 248 2e-66 2V65-A nrPDB 246 8e-66 1V6A-A nrPDB 246 1e-65 4ROS-A nrPDB 240 8e-64 3GVH-A nrPDB 239 2e-63 1GUZ-A nrPDB 236 1e-62 1LTH-T nrPDB 236 1e-62 3D0O-A nrPDB 234 4e-62 2HJR-A nrPDB 234 4e-62 1GV0-A nrPDB 234 4e-62 3TL2-A nrPDB 234 4e-62 3P7M-A nrPDB 234 5e-62 2LDB-A nrPDB 233 7e-62 1SOW-A nrPDB 231 2e-61 1A5Z-A nrPDB 231 3e-61 4M1Q-A nrPDB 230 1e-60 6J9S-A nrPDB 226 7e-60 4BGV-A nrPDB 226 1e-59 4Q3N-A nrPDB 224 4e-59 6H9S-A nrPDB 223 6e-59 6CT6-A nrPDB 223 7e-59 1UXJ-A nrPDB 221 4e-58 3NEP-X nrPDB 218 4e-57 1Y6J-A nrPDB 217 5e-57 3WSV-A nrPDB 214 5e-56 1EZ4-A nrPDB 211 3e-55 3ZZN-A nrPDB 208 2e-54 5MDH-A nrPDB 208 3e-54 4UUP-A nrPDB 201 4e-52 1PZF-A nrPDB 196 1e-50 1T24-A nrPDB 196 1e-50 5NFR-A nrPDB 193 9e-50 5HTO-A nrPDB 193 1e-49 1HYE-A nrPDB 193 1e-49 1OC4-A nrPDB 193 1e-49 5NUE-A nrPDB 192 1e-49 2V6B-A nrPDB 190 9e-49 4ND4-A nrPDB 189 1e-48 3FI9-A nrPDB 189 1e-48 4I1I-A nrPDB 187 7e-48 2D4A-B nrPDB 186 1e-47 4UUO-A nrPDB 185 2e-47 2X0J-A nrPDB 185 2e-47 4KDE-A nrPDB 183 1e-46 7MDH-A nrPDB 179 2e-45 1CIV-A nrPDB 177 6e-45 4BGU-A nrPDB 174 5e-44 4JCO-A nrPDB 170 6e-43 4UUM-A nrPDB 162 2e-40 3DL2-A nrPDB 153 1e-37 1B8U-A nrPDB 152 2e-37 6IHE-A nrPDB 146 1e-35 Sequences not found previously or not previously below threshold: 2LDX-A nrPDB 233 1e-61 3LDH-A nrPDB 195 2e-50 3D5T-A nrPDB 160 6e-40 4TVO-A nrPDB 153 1e-37 1HYH-A nrPDB 126 2e-29 3FEF-A nrPDB 38 0.005 3PLN-A nrPDB 37 0.008 4XRR-A nrPDB 36 0.032 1HE4-A nrPDB 35 0.039 3WMX-A nrPDB 34 0.081 5K0S-A nrPDB 34 0.092 3GRP-A nrPDB 34 0.092 3WYE-A nrPDB 33 0.18 1ORR-A nrPDB 33 0.21 4F3Y-A nrPDB 32 0.26 5C3M-A nrPDB 32 0.26 4NBV-A nrPDB 32 0.26 2EW8-A nrPDB 32 0.27 5ZF1-A nrPDB 32 0.51 1GEG-A nrPDB 31 0.63 2BE7-D nrPDB 31 0.66 1BXK-A nrPDB 31 0.73 5UYY-A nrPDB 31 0.76 1KEU-A nrPDB 31 0.77 5EES-A nrPDB 31 0.85 2GFQ-A nrPDB 31 0.89 2CVO-A nrPDB 31 0.96 4WOK-A nrPDB 31 1.2 3WTC-A nrPDB 31 1.2 2YV3-A nrPDB 31 1.2 2NNL-D nrPDB 31 1.2 4A7P-A nrPDB 30 1.4 3RFT-A nrPDB 30 1.5 2Q1W-A nrPDB 30 1.5 1LSS-A nrPDB 30 1.5 3G05-A nrPDB 30 1.6 3CP2-A nrPDB 30 1.9 5JW6-A nrPDB 30 2.0 5ITV-A nrPDB 30 2.0 4B4O-A nrPDB 30 2.1 1E3W-A nrPDB 29 2.3 5TEK-A nrPDB 29 2.3 2FV8-A nrPDB 29 2.4 3PWZ-A nrPDB 29 2.6 3RSH-A nrPDB 29 2.7 2C54-A nrPDB 29 2.8 6BI4-A nrPDB 29 3.2 1YS4-A nrPDB 29 3.2 5JCP-B nrPDB 29 3.2 3PZR-A nrPDB 29 3.2 5G4J-A nrPDB 29 3.3 3PRY-A nrPDB 29 3.4 3EMK-A nrPDB 29 3.5 2ZJ1-A nrPDB 29 3.6 5TEN-A nrPDB 29 3.8 4G65-A nrPDB 29 3.8 2R00-A nrPDB 29 3.9 2EP5-A nrPDB 29 3.9 3TZ6-A nrPDB 29 3.9 4MOW-A nrPDB 29 4.3 2BKA-A nrPDB 29 4.3 3W9B-A nrPDB 29 4.4 4YWJ-A nrPDB 29 4.6 2GAS-A nrPDB 29 4.6 6BMQ-A nrPDB 29 4.6 5C2K-A nrPDB 28 4.8 5ZHX-e nrPDB 28 4.9 3SXP-A nrPDB 28 4.9 2O3J-A nrPDB 28 5.0 5FWK-A nrPDB 28 5.0 2O23-A nrPDB 28 5.0 1QWG-A nrPDB 28 5.2 3I83-A nrPDB 28 5.2 2X86-A nrPDB 28 5.5 1EQ2-A nrPDB 28 5.5 3UW3-A nrPDB 28 5.6 6EL3-D nrPDB 28 5.6 2Z2C-A nrPDB 28 5.7 3PWS-A nrPDB 28 5.8 3N58-A nrPDB 28 5.9 1MV8-A nrPDB 28 6.3 4RFL-A nrPDB 28 6.7 3SQG-A nrPDB 28 7.0 3EH7-A nrPDB 28 7.6 4J6F-A nrPDB 27 8.6 4WOJ-A nrPDB 27 8.7 6QUZ-A nrPDB 27 9.0 3Q98-A nrPDB 27 9.0 >5ZI4-A nrPDB Length = 345 Score = 395 bits (1015), Expect = e-110, Method: Composition-based stats. Identities = 343/343 (100%), Positives = 343/343 (100%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD Sbjct: 3 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 62 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV Sbjct: 63 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 122 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK Sbjct: 123 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 182 Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA Sbjct: 183 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 242 Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV Sbjct: 243 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 302 Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 343 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL Sbjct: 303 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 345 >1MLD-A nrPDB Length = 314 Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats. Identities = 144/337 (42%), Positives = 197/337 (58%), Gaps = 30/337 (8%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61 KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY + Sbjct: 2 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQ 61 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 + + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P+A I +ISNPVN Sbjct: 62 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPDAMICIISNPVN 121 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181 S +PI E KK G + P + GVT LD+VRA F+ + L ++ V Sbjct: 122 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLDPARV-----------SV 170 Query: 182 TVIGGHSGETIIPIITDKSL-VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240 VIGGH+G+TIIP+I+ + V Q R+Q G E+VKAK GAGSATLSMA+A Sbjct: 171 PVIGGHAGKTIIPLISQCTPKVDFPQDQLSTLTGRIQEAGTEVVKAKAGAGSATLSMAYA 230 Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300 GA+F ++ + + ++ E +FV + YFS P++L + Sbjct: 231 GARFVFSLVDAMNGKEGVVE--CSFVKSQ-------------ETDCPYFSTPLLLGKKGI 275 Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 + K+SP EE+++ A+ EL+ +I+KG+ F+ Sbjct: 276 EKNLG--IGKISPFEEKMIAEAIPELKASIKKGEEFV 310 >4E0B-A nrPDB Length = 313 Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats. Identities = 132/338 (39%), Positives = 187/338 (55%), Gaps = 31/338 (9%) Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDI-RAAEGIGKDLSHINTNSSCVGYDK 59 +KVA++GA+GG+GQ L+LLLK P S+LALYDI G+ DLSHI T+ S GY Sbjct: 4 MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTHVSIKGYAG 63 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + L A VVLI AGV RKPG+ R DLF +NAGIVKSL + PNA I +I+NP Sbjct: 64 EDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACIGIITNP 123 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 VN+ VPIA E LKK G + + GVT LD++R+ETF+ + LK G+ Sbjct: 124 VNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAE---LKGQDPGE--------V 172 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 +V VIGGHSG TI+P+++ V D++ R+Q G E+V+AK G GSATLSM Sbjct: 173 RVPVIGGHSGVTILPLLSQVEGVEFSDEEIAALTKRIQNAGTEVVEAKAGGGSATLSMGQ 232 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 A +F ++++ E+ + + Y+ G +F+ P+ L Sbjct: 233 AACRFGLALVKALQGEE-----VIEYAYVEGNGEHAS-----------FFAQPVKLGKEG 276 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V I +LS E+ ++ ++ L +I+ G F+ Sbjct: 277 VEEI--LPYGELSDFEKAALDGMLETLNSDIQIGVDFV 312 >4WLE-A nrPDB Length = 340 Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats. Identities = 144/337 (42%), Positives = 197/337 (58%), Gaps = 30/337 (8%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61 KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY + Sbjct: 28 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQ 87 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 + + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P A I VI+NPVN Sbjct: 88 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVN 147 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181 S +PI E KK G + P + GVT LD+VRA TF+ + L ++ V Sbjct: 148 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARV-----------NV 196 Query: 182 TVIGGHSGETIIPIITDKSL-VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240 VIGGH+G+TIIP+I+ + V Q R+Q G E+VKAK GAGSATLSMA+A Sbjct: 197 PVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYA 256 Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300 GA+F ++ + + ++ E +FV + YFS P++L + Sbjct: 257 GARFVFSLVDAMNGKEGVVE--CSFVKSQ-------------ETECTYFSTPLLLGKKGI 301 Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 + K+S EE++++ A+ EL+ +I+KG+ F+ Sbjct: 302 EKNLG--IGKVSSFEEKMISDAIPELKASIKKGEDFV 336 >4L4S-H nrPDB Length = 339 Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats. Identities = 79/344 (22%), Positives = 144/344 (41%), Gaps = 41/344 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + + ELAL D+ +G DL H + Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSG 79 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 N +N+++V+I AG ++ G +R +L + N I K ++ V K++PN ++L++SNPV Sbjct: 80 KDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPV 139 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174 + L +A K+ F V+G NLD R + + L + +G+ D Sbjct: 140 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDS 195 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233 + + G S +T+ P L DK+ +H+ V E++K K G Sbjct: 196 SVPVWSGMNVAGVSLKTLHPD-----LGTDKDKEQWKEVHKQVVESAYEVIKLK---GYT 247 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 + ++ + A AE ++++ P + + + L G + S+P Sbjct: 248 SWAIGLSVADLAESIMKNLRRVHPVSTMI---------------KGLYGIKDDVFLSVPC 292 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 +L I V L+ EE + + L I+K F+ Sbjct: 293 ILGQNG---ISDLVKVTLTSEEEARLKKSADTLWG-IQKELQFL 332 >5NQB-A nrPDB Length = 332 Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats. Identities = 79/343 (23%), Positives = 144/343 (41%), Gaps = 41/343 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + + ELAL D+ +G DL H + Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + +N+++V+I AG ++ G +R +L + N I K ++ V K++P+ ++LV+SNPV Sbjct: 81 KDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPHCKLLVVSNPV 140 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLML-----KNPKIGQEQDK 174 + L +A K+ F V+G NLD R + + L + +G+ D Sbjct: 141 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWILGEHGDS 196 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233 + + G S +T+ P L DK+ +H+ V E++K K G Sbjct: 197 SVPVWSGMNVAGVSLKTLHP-----ELGTDADKEQWKQVHKQVVDSAYEVIKLK---GYT 248 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 + ++ + A AE ++++ P + L + L G + S+P Sbjct: 249 SWAIGLSVADLAESIMKNLRRVHPISTML---------------KGLYGIKEDVFLSVPC 293 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 VL + + V L+ EE + + L I+K F Sbjct: 294 VLGQNGISDV---VKVTLTSEEEAHLKKSADTLWG-IQKELQF 332 >1IE3-A nrPDB Length = 312 Score = 267 bits (682), Expect = 6e-72, Method: Composition-based stats. Identities = 130/338 (38%), Positives = 184/338 (54%), Gaps = 30/338 (8%) Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDI-RAAEGIGKDLSHINTNSSCVGYDK 59 +KVA+LGA+GG+GQ L+LLLK P SEL+LYDI G+ DLSHI T G+ Sbjct: 1 MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSG 60 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + L A VVLI AGV RKPG+ R DLF +NAGIVK+LV V K P A I +I+NP Sbjct: 61 EDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNP 120 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 VN+ V IA E LKK G + + GVT LD++ + TF+ + + ++ Sbjct: 121 VNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIICSNTFVAELKGKQPGEV----------- 169 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 +V VIGGHSG TI+P+++ V +++ R+Q G E+V+AK G GSATLSM Sbjct: 170 EVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQ 229 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 A A+F ++R+ E+ E A+V G +FS P++L Sbjct: 230 AAARFGLSLVRALQGEQGVVE--CAYVEGDGQY-------------ARFFSQPLLLGKNG 274 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V + + LS E+ + + L+K+I G+ F+ Sbjct: 275 VE--ERKSIGTLSAFEQNALEGMLDTLKKDIALGQEFV 310 >4PLW-A nrPDB Length = 326 Score = 267 bits (681), Expect = 7e-72, Method: Composition-based stats. Identities = 86/351 (24%), Positives = 160/351 (45%), Gaps = 55/351 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K++++GA G +G L+ L+ + ++ L+DI GK L I+ +S +G + Sbjct: 6 KISLIGA-GNIGGTLAHLIA-QKELGDVVLFDIVEGMPQGKALD-ISHSSPIMGSNVKIT 62 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + + + VV+I AG+PRKPG++RDDL +NA I+K + + K+ PNA ++V++N Sbjct: 63 GTNNYEDIKGSDVVIITAGIPRKPGMSRDDLLSVNAKIMKDVAENIKKYCPNAFVIVVTN 122 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++ +V + L K V G+ LD R FL + L + + Sbjct: 123 PLDVMVYV----LHKYSGLPHNKVCGMAGVLDSSRFRYFLAEKLNVSPNDV--------- 169 Query: 178 HRKVTVIGGHSGETIIPIITDKSL-----------VFQLDKQYEHFIHRVQFGGDEIVKA 226 + VIGGH G+T++P+ ++ + ++ + + R + G EIV Sbjct: 170 --QAMVIGGH-GDTMVPLTRYCTVGGIPLTEFIKQGWITQEEIDEIVERTRNAGGEIVNL 226 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286 + GSA + A + + AE L+ P YL G K Sbjct: 227 LK-TGSAYFAPAASAIEMAESYLKDKKRILPC------SAYLEGQYGVKDL--------- 270 Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 + +P+++ V I + +L+ E+++ + +V+ +R+ +E K Sbjct: 271 -FVGVPVIIGKNGVEKI---IELELTEEEQEMFDKSVESVRELVETVKKLN 317 >9LDB-A nrPDB Length = 332 Score = 267 bits (681), Expect = 7e-72, Method: Composition-based stats. Identities = 77/343 (22%), Positives = 145/343 (42%), Gaps = 41/343 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + + E+AL D+ +G DL H + Sbjct: 22 KITVVGV-GAVGMACAISILMKELADEIALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 N +N+++V+I AG ++ G +R +L + N I K ++ + K++PN ++LV+SNPV Sbjct: 81 KDYNVTANSRLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCKLLVVSNPV 140 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174 + L +A K+ F V+G NLD R + + L + +G+ D Sbjct: 141 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWILGEHGDS 196 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233 + + G S + + P L DK++ +H+ V E++K K G Sbjct: 197 SVPVWSGVNVAGVSLKNLHP-----ELGTDADKEHWKAVHKEVVDSAYEVIKLK---GYT 248 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 + ++ + A AE ++++ P + + + L G + S+P Sbjct: 249 SWAIGLSVADLAESIMKNLRRVHPISTMI---------------KGLYGIKENVFLSVPC 293 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 +L + + V L+P EE + + L I+K F Sbjct: 294 ILGQNGISDV---VKVTLTPEEEAHLKKSADTLWG-IQKELQF 332 >1SMK-A nrPDB Length = 326 Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats. Identities = 139/337 (41%), Positives = 197/337 (58%), Gaps = 30/337 (8%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61 KVAILGA+GG+GQPL++L+K++P VS L LYD+ A G+ D+SH++T + G+ + Sbjct: 10 KVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQ 69 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 +E L+ ++++PAGVPRKPG+TRDDLFK+NAGIVK+L + K P A + +ISNPVN Sbjct: 70 LEAALTGMDLIIVPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPRAIVNLISNPVN 129 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181 S VPIA E KK G + P ++GVT LD+VRA TF+ + L L + V Sbjct: 130 STVPIAAEVFKKAGTYDPKRLLGVTMLDVVRANTFVAEVLGLDPRDV-----------DV 178 Query: 182 TVIGGHSGETIIPIITD-KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240 V+GGH+G TI+P+++ K ++ + R+Q GG E+V+AK GAGSATLSMA+A Sbjct: 179 PVVGGHAGVTILPLLSQVKPPSSFTQEEISYLTDRIQNGGTEVVEAKAGAGSATLSMAYA 238 Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300 KFA+ LR + E AFV + +F+ + L + Sbjct: 239 AVKFADACLRGLRGDAGVIE--CAFVSSQ-------------VTELPFFASKVRLGRNGI 283 Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 + L L+ E + A KEL +IEKG SFI Sbjct: 284 EEV--YSLGPLNEYERIGLEKAKKELAGSIEKGVSFI 318 >4AJN-A nrPDB Length = 331 Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats. Identities = 76/343 (22%), Positives = 144/343 (41%), Gaps = 41/343 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + + ELAL D+ +G DL H + Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSS 79 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + +N+++V+I AG ++ G +R +L + N I K ++ V K++P ++L++SNPV Sbjct: 80 KDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSNPV 139 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174 + L +A K+ F V+G NLD R + + L + +G+ D Sbjct: 140 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDS 195 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233 + + G S +++ P L DK+ +H+ V E++K K G Sbjct: 196 SVPVWSGVNVAGVSLKSLNP-----QLGTDADKEQWKDVHKQVVDSAYEVIKLK---GYT 247 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 + ++ + A AE ++++ P + + + L G + S+P Sbjct: 248 SWAIGLSVADLAESIMKNLRRVHPISTMI---------------KGLYGIKEDVFLSVPC 292 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 +L + + V L+P EE + + L I+K F Sbjct: 293 ILGQNGISDV---VKVTLTPDEEARLKKSADTLWG-IQKELQF 331 >6BAL-A nrPDB Length = 335 Score = 261 bits (666), Expect = 4e-70, Method: Composition-based stats. Identities = 132/338 (39%), Positives = 187/338 (55%), Gaps = 31/338 (9%) Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDI-RAAEGIGKDLSHINTNSSCVGYDK 59 +KVA+LGA+GG+GQ L+LLLKL P ++L+LYDI G+ D+SHI T + G+ Sbjct: 25 MKVAVLGAAGGIGQALALLLKLQLPAGTDLSLYDIAPVTPGVAVDVSHIPTAVNVKGFSG 84 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + L A VVLI AGV RKPG+ R DLF +NAGIV+ L+ V P A + +I+NP Sbjct: 85 EDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRGLIEKVAVTCPKACVGIITNP 144 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 VN+ V IA E LKK G + + GVT LD++R+ETF+ + L + Sbjct: 145 VNTTVAIAAEVLKKAGVYDKRKLFGVTTLDVLRSETFVAELKGLNVSRT----------- 193 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 V VIGGHSG TI+P+++ + + E R+Q G E++ AK G GSATLSMA Sbjct: 194 SVPVIGGHSGVTILPLLSQVQYAKWNEDEIEPLTKRIQNAGTEVLNAKAGGGSATLSMAQ 253 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 A A+FA +++ E++ Y+ G +GK A+ +FS P+ L Sbjct: 254 AAARFARSLVKGL-----SGETVVECTYVEG--DGKYAR---------FFSQPVRLGKEG 297 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V I + LS E+Q + + LR +IE G+ FI Sbjct: 298 VEEI--LPIGPLSNFEQQALENMLPTLRADIELGEKFI 333 >1LDM-A nrPDB Length = 329 Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats. Identities = 73/342 (21%), Positives = 137/342 (40%), Gaps = 42/342 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + + E+AL D+ +G DL H + Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG 80 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + + +++V+I AG ++ G +R +L + N I K ++ + K +P+ ILV+SNPV Sbjct: 81 KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVVSNPV 140 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLML-----KNPKIGQEQDK 174 + L +A K+ ++G NLD R + + L + IG+ D Sbjct: 141 DVLTYVA----WKLSGLPMHRIIGSGCNLDSARFRYLMGERLGVHSCSCHGWVIGEHGDS 196 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234 + + P+ + + ++ V E++K K G + Sbjct: 197 VPSVWSGMNVASIK---LHPL----DGTNKDKQDWKKLHKDVVDSAYEVIKLK---GYTS 246 Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294 ++ + A AE ++++ P + + F G + SLP V Sbjct: 247 WAIGLSVADLAETIMKNLCRVHPVSTMVKDF---------------YGIKDNVFLSLPCV 291 Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 L + + +I V KL P EEQ + + L +I+K F Sbjct: 292 LNDHGISNI---VKMKLKPNEEQQLQKSATTLW-DIQKDLKF 329 >4PLF-A nrPDB Length = 334 Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats. Identities = 84/360 (23%), Positives = 154/360 (42%), Gaps = 64/360 (17%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSH----INTNSSCVG 56 K++++G SG +G ++ L + ++ L+D+ +G DLSH +TN G Sbjct: 10 KISLIG-SGMIGGTMAYLCA-QKELGDVVLFDVVKNMPQGKALDLSHSSSIADTNVKVTG 67 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111 + + + VV+I AG+ + PG +RDDL NA I++ + + K+ PNA Sbjct: 68 TNS---YEDIKGSDVVIITAGLTKAPGKSDKEWSRDDLLPFNAKIMREVGENIKKYCPNA 124 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQ 170 ++VI+NP++ +V + L + V G+ LD R F+ + L + + Sbjct: 125 FVIVITNPLDVMVKV----LHEHSGLPKNKVCGMAGVLDSSRFRHFIAEKLNVSPRDV-- 178 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVF-----------QLDKQYEHFIHRVQFG 219 + VIG H G+ ++P+ ++ ++ + + R + Sbjct: 179 ---------QAMVIGAH-GDKMVPLTRYVTVNGIPLQEFIKKGRITQEEIDEIVERTKNA 228 Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQ 279 G EIV G GSA + A + + AE L+ L YL G K Sbjct: 229 GGEIVNLL-GQGSAYFAPAASAIEMAEAYLKDKKRV------LVCSCYLEGQYGHKDM-- 279 Query: 280 LVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILD 339 + +P V+ V + +L+P E++L + +V+E+RK + K+ L+ Sbjct: 280 --------FVGVPAVIGGNGVEKVIEL---ELTPEEKELFDKSVEEVRKLQKAIKALGLE 328 >6CEP-A nrPDB Length = 334 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 71/343 (20%), Positives = 138/343 (40%), Gaps = 40/343 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + ELAL D+ +G DL H + D Sbjct: 23 KITVVGV-GQVGMACAISILGKSLTDELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + +N+++V++ AGV ++ G +R +L + N + K ++ + K++P+ I+V+SNPV Sbjct: 82 KDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPV 141 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174 + L + K+ V+G NLD R + + L + +G+ D Sbjct: 142 DILTYVT----WKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGVHPSSCHGWILGEHGDS 197 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233 + + G S + + P + D + +H+ V E++K K G Sbjct: 198 SVAVWSGVNVAGVSLQELNP-----EMGTDNDSENWKEVHKMVVESAYEVIKLK---GYT 249 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 ++ + A E +L++ P + + Q + G + + SLP Sbjct: 250 NWAIGLSVADLIESMLKNLSRIHPVSTMV---------------QGMYGIENEVFLSLPC 294 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 VL + S+ + +KL E + + L + K Sbjct: 295 VLNARGLTSV---INQKLKDDEVAQLKNSADTLWGIQKDLKDL 334 >4LN1-A nrPDB Length = 336 Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats. Identities = 80/343 (23%), Positives = 131/343 (38%), Gaps = 54/343 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60 +V ++G +G VG + + E L D+ AEG DLSH + Sbjct: 29 RVVLVG-TGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWK 87 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 +A +V+I AG+P+KPG TR DL + NA I K +V ++ + L+ +NPV Sbjct: 88 GSYEDCKDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPV 147 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 + L + K V+G T LD R L +Y + I Sbjct: 148 DILTYVT----WKESGLPKERVIGSGTTLDSARFRYMLGEYFDIGPHNI----------- 192 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQ------------LDKQYEHFIHRVQFGGDEIVKAK 227 +IG H G+T +P+ + S+ Q + + V+ I++ K Sbjct: 193 HAYIIGEH-GDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFINVRDAAYHIIERK 251 Query: 228 QGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE 287 G+ + + + + +L E L+ YL G K Sbjct: 252 ---GATYYGIGMSLLRVTKAILND------ENSVLTVSAYLEGQYGQKD----------V 292 Query: 288 YFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNI 330 Y +P VL G V I +LS EE + +V+ L++ + Sbjct: 293 YIGVPAVLNRGGVREILEV---ELSEDEELKFDHSVQVLKETM 332 >3PQF-A nrPDB Length = 326 Score = 249 bits (635), Expect = 2e-66, Method: Composition-based stats. Identities = 73/337 (21%), Positives = 122/337 (36%), Gaps = 40/337 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKD 60 KVA++GA G VG + L EL + D+ A G DL+H + Sbjct: 7 KVALIGA-GFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLNHGKAFAPQPVKTSY 65 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 +A +V I AG +KPG TR +L + N I K +V+ V + LV +NPV Sbjct: 66 GTYEDCKDADIVCICAGANQKPGETRLELVEKNLKIFKGIVSEVMASGFDGIFLVATNPV 125 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNP-----KIGQEQDK 174 + L K V+G T LD R L +Y IG+ D Sbjct: 126 DILTY----ATWKFSGLPKERVIGSGTTLDSARFRFMLSEYFGAAPQNVCAHIIGEHGDT 181 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234 +GG ++ ++ + + V+ I++ K G+ Sbjct: 182 ELPVWSHANVGGVPVSELVE-----KNDAYKQEELDQIVDDVKNAAYHIIEKK---GATY 233 Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294 +A + A+ + +L + E L+ YL G Y +P V Sbjct: 234 YGVAMSLARITKAILHN------ENSILTVSTYLDGQYGA----------DDVYIGVPAV 277 Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331 + G + I L+ +E++ + L+ ++ Sbjct: 278 VNRGGIAGITEL---NLNEKEKEQFLHSAGVLKNILK 311 >5K0Z-A nrPDB Length = 331 Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats. Identities = 70/342 (20%), Positives = 137/342 (40%), Gaps = 40/342 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G G VG ++ + ELAL D+ +G DL H + D Sbjct: 21 KITVVGV-GQVGMACAISILGKGLCDELALVDVLEDKLKGEMMDLQHGSLFLQTHKIVAD 79 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 +N+++V++ AGV ++ G +R +L + N + K ++ + K++PN ILV+SNPV Sbjct: 80 KDYAVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPNCTILVVSNPV 139 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174 + L + K+ V+G NLD R + + L + +G+ D Sbjct: 140 DILTYVT----WKLSGLPKHRVIGSGCNLDTARFRYLMAERLGIHPTSCHGWILGEHGDS 195 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233 + + G S + + P + D + +H+ V E+++ K G Sbjct: 196 SVAVWSGVNVAGVSLQELNPAM-----GTDKDSENWKEVHKQVVESAYEVIRLK---GYT 247 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 ++ + A+ E +L++ + + + + G + + SLP Sbjct: 248 NWAIGLSVAELCETMLKNLYRVHSVSTLV---------------KGTYGIENDVFLSLPC 292 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335 VL + S+ + +KL E + + L + K Sbjct: 293 VLSASGLTSV---INQKLKDDEVAQLKKSADTLWSIQKDLKD 331 >2V65-A nrPDB Length = 331 Score = 246 bits (629), Expect = 8e-66, Method: Composition-based stats. Identities = 71/322 (22%), Positives = 134/322 (41%), Gaps = 40/322 (12%) Query: 16 PLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVL 73 ++ + L ELA+ D+ +G DL H + D + +N++VV+ Sbjct: 34 ASAISILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIV-GDKDYSVTANSKVVV 92 Query: 74 IPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKK 133 + AG ++ G +R +L + N I K ++ + K++PN ++V+SNPV+ L +A K Sbjct: 93 VTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVA----WK 148 Query: 134 MGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDKTTMHRKVTVIGGH 187 + F V+G TNLD R + + L L +G+ D + + G Sbjct: 149 LSGFPRHRVIGSGTNLDSARFRHLIGEKLHLHPSSCHAWIVGEHGDSSVPVWSGVNVAGV 208 Query: 188 SGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMAFAGAKFAE 246 S + + P + + D + IH+ V G E++K K G + ++ + A E Sbjct: 209 SLQGLNP-----QMGTEGDGENWKAIHKEVVDGAYEVIKLK---GYTSWAIGMSVADLVE 260 Query: 247 EVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTS 306 ++++ H P + + Q + G + S+P VL N + + Sbjct: 261 SIIKNMHKVHPVSTLV---------------QGMHGVKDEVFLSVPCVLGNSGLTDVIHM 305 Query: 307 VLEKLSPREEQLVNTAVKELRK 328 L EE+ + + + L Sbjct: 306 T---LKAEEEKQLQKSAETLWG 324 >1V6A-A nrPDB Length = 332 Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats. Identities = 71/324 (21%), Positives = 134/324 (41%), Gaps = 39/324 (12%) Query: 19 LLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLIPA 76 + + L ELAL D+ +G DL H + D + +N++VV++ A Sbjct: 37 ISILLKDLTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTANSKVVVVTA 96 Query: 77 GVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGK 136 G ++ G +R +L + N I K ++ + K++PN +LV+SNPV+ L +A K+ Sbjct: 97 GARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVA----WKLSG 152 Query: 137 FKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDKTTMHRKVTVIGGHSGE 190 V+G TNLD R + + L + IG+ D + + G + Sbjct: 153 LPRNRVIGSGTNLDSARFRHLMGEKLGIHPSNCHGWVIGEHGDSSVPVWSGVNVAGVFLQ 212 Query: 191 TIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVL 249 + P + DK+ +H+ V E++K K G + ++ + A + +L Sbjct: 213 GLNPDM-----GTDKDKEDWKSVHKMVVDSAYEVIKLK---GYTSWAIGMSAADLCQSIL 264 Query: 250 RSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLE 309 ++ P + + + + G N + S+P +L N + + L+ Sbjct: 265 KNLRKCHPVSTLV---------------KGMHGVNEEVFLSVPCILGNSGLTDVVHMTLK 309 Query: 310 KLSPREEQLVNTAVKELRKNIEKG 333 S E+QLV + + L + Sbjct: 310 --SDEEKQLV-KSAETLWGVQKDL 330 >4ROS-A nrPDB Length = 320 Score = 240 bits (611), Expect = 8e-64, Method: Composition-based stats. Identities = 84/345 (24%), Positives = 150/345 (43%), Gaps = 43/345 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K+A++GA G +G L+ L L + ++ L+DI GK L I ++ G+D Sbjct: 5 KIALIGA-GQIGGTLAHLAGLKE-LGDVVLFDIVDGVPQGKALD-IAESAPVDGFDAKYS 61 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 S + ++ A VV++ AGVPRKPG++RDDL +N +++++ + + AP+A ++ I+N Sbjct: 62 GASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGAGIKEHAPDAFVICITN 121 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQEQ 172 P++++V L+K V+G+ LD R FL + + + G Sbjct: 122 PLDAMV----WALQKFSGLPTNKVVGMAGVLDSARFRHFLAEEFGVSVEDVTAFVLGGHG 177 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232 D + + + G +P+ L + ++ + + R + GG EIV + GS Sbjct: 178 DDMVPLTRYSTVAG------VPLTDLVKLGWTTQEKLDAMVERTRKGGGEIVNLLK-TGS 230 Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292 A + A + AE LR P L + GL Y +P Sbjct: 231 AFYAPAASAIAMAESYLRDKKRVLPCAAYLDGQYGIDGL----------------YVGVP 274 Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 +V+ V + + E+ + +V ++ IE KS Sbjct: 275 VVIGENGVERVLEVT---FNDDEKAMFEKSVNSVKGLIEACKSVN 316 >3GVH-A nrPDB Length = 324 Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats. Identities = 85/339 (25%), Positives = 142/339 (41%), Gaps = 43/339 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K+A++G SG +G L+ L L + ++ L+DI GK L I +S G+D Sbjct: 9 KIALIG-SGMIGGTLAHLAGLKE-LGDVVLFDIAEGTPQGKGLD-IAESSPVDGFDAKFT 65 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + + A VV++ AGVPRKPG++RDDL +N +++ + + K+AP A ++ I+N Sbjct: 66 GANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITN 125 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQEQ 172 P++++V L+K V+G+ LD R FL + + + G Sbjct: 126 PLDAMV----WALQKFSGLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTVFVLGGHG 181 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232 D + + + G IP+ + + + + I R + GG EIV + GS Sbjct: 182 DSMVPLARYSTVAG------IPLPDLVKMGWTSQDKLDKIIQRTRDGGAEIVGLLK-TGS 234 Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292 A + A + + AE L+ P LS G K Y +P Sbjct: 235 AFYAPAASAIQMAESYLKDKKRVLPVAAQLS------GQYGVKDM----------YVGVP 278 Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331 V+ V I L E+ + +V + E Sbjct: 279 TVIGANGVERIIEI---DLDKDEKAQFDKSVASVAGLCE 314 >1GUZ-A nrPDB Length = 310 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 82/347 (23%), Positives = 144/347 (41%), Gaps = 49/347 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD--- 58 +K+ ++GA G VG + L EL L D+ GK L + + +D Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDVVEGIPQGKALD-MYESGPVGLFDTKV 58 Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 + +N+ +V+I AG+PRKPG+TR+DL NAGIVK + + K + N I+V+S Sbjct: 59 TGSNDYADTANSDIVIITAGLPRKPGMTREDLLMKNAGIVKEVTDNIMKHSKNPIIIVVS 118 Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 NP++ + +A V+G+ LD R +F+ L + I Sbjct: 119 NPLDIMTHVA----WVRSGLPKERVIGMAGVLDAARFRSFIAMELGVSMQDI-------- 166 Query: 177 MHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKAKQGA 230 V+GGH G+ ++P++ ++ + + + R + GG EIV+ + Sbjct: 167 ---NACVLGGH-GDAMVPVVKYTTVAGIPISDLLPAETIDKLVERTRNGGAEIVEHLK-Q 221 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290 GSA + A + + E ++ P V L G + Sbjct: 222 GSAFYAPASSVVEMVESIVLDRKRVLPCA------VGLEGQYG----------IDKTFVG 265 Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 +P+ L V I L++ + L+ + K + +N + +S I Sbjct: 266 VPVKLGRNGVEQIYEINLDQA---DLDLLQKSAKIVDENCKMLESTI 309 >1LTH-T nrPDB Length = 319 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 74/336 (22%), Positives = 129/336 (38%), Gaps = 38/336 (11%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDK 59 K+A++GA G VG L+ E+ L DI E D+ H ++ V D Sbjct: 8 TKLAVIGA-GAVGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDG 66 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 +A +V+I AG +KPG +R +L I+K+++ + K APNA ++I+NP Sbjct: 67 SDDPEICRDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNP 126 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLM-----LKNPKIGQEQD 173 V+ +A +K+ + G TNLD R + + G+ D Sbjct: 127 VDIATHVA----QKLTGLPENQIFGSGTNLDSARLRFLIAQQTGVNVKNVHAYIAGEHGD 182 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233 + IGG P+ L DK+ E V+ +I+ K G+ Sbjct: 183 SEVPLWESATIGGVPMSDWTPLPGHDPL--DADKR-EEIHQEVKNAAYKIINGK---GAT 236 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 ++ +G E VL + P + L F + + S+P Sbjct: 237 NYAIGMSGVDIIEAVLHDTNRILPVSSMLKDFHGISDIC----------------MSVPT 280 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKN 329 +L V + + +S +E + + + L++ Sbjct: 281 LLNRQGVNNTINT---PVSDKELAALKRSAETLKET 313 >3D0O-A nrPDB Length = 317 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 76/342 (22%), Positives = 123/342 (35%), Gaps = 41/342 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60 KV ++G +G VG + L V EL + D+ G DL H S K Sbjct: 8 KVVLIG-NGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKA 66 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + +A +V+I AG +KPG TR DL N I KS+V V + LV +NPV Sbjct: 67 GEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPV 126 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174 + L K V+G T LD R L + + IG+ D Sbjct: 127 DILAY----ATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDT 182 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234 I G +T++ + Q E + + +I++AK G+ Sbjct: 183 ELPVWSHANIAGQPLKTLLEQ------RPEGKAQIEQIFVQTRDAAYDIIQAK---GATY 233 Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294 +A A+ E + R+ E L+ L G + Y +P V Sbjct: 234 YGVAMGLARITEAIFRN------EDAVLTVSALLEGEY----------EEEDVYIGVPAV 277 Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 + + ++ L+ E+ + K L+ + + + Sbjct: 278 INRNGIRNVVEI---PLNDEEQSKFAHSAKTLKDIMAEAEEL 316 >2HJR-A nrPDB Length = 328 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 95/352 (26%), Positives = 158/352 (44%), Gaps = 55/352 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINT--NSSCVGYD 58 K++I+GA G +G ++LLL + ++ ++DI +G DL+H S + Sbjct: 16 KISIIGA-GQIGSTIALLLGQKD-LGDVYMFDIIEGVPQGKALDLNHCMALIGSPAKIFG 73 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 +++ E L N+ VV+I AGVPRKP +TR DL +NA IV S+ VGK+ PNA ++ I+N Sbjct: 74 ENNYE-YLQNSDVVIITAGVPRKPNMTRSDLLTVNAKIVGSVAENVGKYCPNAFVICITN 132 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++++V K+ V G++ LD R L L +K + Sbjct: 133 PLDAMVY----YFKEKSGIPANKVCGMSGVLDSARFRCNLSRALGVKPSDV--------- 179 Query: 178 HRKVTVIGGHSGETIIPIITDKSL-----------VFQLDKQYEHFIHRVQFGGDEIVKA 226 V+GGH G+ +IP+ + ++ Q I + FGG EIV+ Sbjct: 180 --SAIVVGGH-GDEMIPLTSSVTIGGILLSDFVEQGKITHSQINEIIKKTAFGGGEIVEL 236 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286 + GSA + A + A+ L+ L YL G N Sbjct: 237 LK-TGSAFYAPAASAVAMAQAYLKD------SKSVLVCSTYLTGQYNVNNL--------- 280 Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338 + +P+V+ I+ V+ LS E+ L + +V+ ++ ++ KS L Sbjct: 281 -FVGVPVVIGKNG---IEDVVIVNLSDDEKSLFSKSVESIQNLVQDLKSLNL 328 >1GV0-A nrPDB Length = 310 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 82/352 (23%), Positives = 147/352 (41%), Gaps = 54/352 (15%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD--- 58 +K+ ++GA G VG + L EL L D+ GK L + + +D Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDVVEGIPQGKALD-MYESGPVGLFDTKV 58 Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 + +N+ +V+I AG+PRKPG+TR+DL MNAGIV+ + + + + N I+V+S Sbjct: 59 TGSNDYADTANSDIVVITAGLPRKPGMTREDLLSMNAGIVREVTGRIMEHSKNPIIVVVS 118 Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 NP++ + +A + V+G+ LD R +F+ L + + Sbjct: 119 NPLDIMTHVA----WQKSGLPKERVIGMAGVLDSARFRSFIAMELGVSMQDVT------- 167 Query: 177 MHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKAKQGA 230 V+GGH G+ ++P++ ++ ++ + R + GG EIV + Sbjct: 168 ----ACVLGGH-GDAMVPVVKYTTVAGIPVADLISAERIAELVERTRTGGAEIVNHLK-Q 221 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290 GSA S A + + E ++ SL + G + Sbjct: 222 GSAFYSPATSVVEMVESIVLDRKRVLTCAVSLDGQYGIDG----------------TFVG 265 Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSK 342 +P+ L V I KL + L+ + K + +N + +LD+S+ Sbjct: 266 VPVKLGKNGVEHIYEI---KLDQSDLDLLQKSAKIVDENCK-----MLDASQ 309 >3TL2-A nrPDB Length = 315 Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats. Identities = 93/344 (27%), Positives = 149/344 (43%), Gaps = 50/344 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG--IGKDLSHINTNSSCVGYDKD 60 KV+++GA G G + LL ++ L DI E GK L + S G+D + Sbjct: 10 KVSVIGA-GFTGATTAFLLAQKELA-DVVLVDIPQLENPTKGKALDML-EASPVQGFDAN 66 Query: 61 ----SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 S +++ VV+I AG+ RKPG++RDDL N+ I+KS+ + K +PNA I+V+ Sbjct: 67 IIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVL 126 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQ 170 +NPV+++ K F V+G + LD R TF+ L L I G Sbjct: 127 TNPVDAMTYSVF----KEAGFPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGG 182 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGA 230 D + + GG ET+IP ++ E + R + GG EIV G Sbjct: 183 HGDDMVPLVRYSYAGGIPLETLIP-----------KERLEAIVERTRKGGGEIVGLL-GN 230 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290 GSA + A + + E +L+ P A YL G S Y Sbjct: 231 GSAYYAPAASLVEMTEAILKDQRRVLP------AIAYLEGEYG----------YSDLYLG 274 Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK 334 +P++L + I +L E++ ++ +V+ +R ++ Sbjct: 275 VPVILGGNGIEKIIEL---ELLADEKEALDRSVESVRNVMKVLV 315 >3P7M-A nrPDB Length = 321 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 82/351 (23%), Positives = 154/351 (43%), Gaps = 54/351 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K+ ++GA G +G L+ L + + ++ L+DI GK L + T G D Sbjct: 7 KITLVGA-GNIGGTLAHLALIKQ-LGDVVLFDIAQGMPNGKALDLLQT-CPIEGVDFKVR 63 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + L N+ VV++ AGVPRKPG++RDDL +N +++++ + PNA ++ I+N Sbjct: 64 GTNDYKDLENSDVVIVTAGVPRKPGMSRDDLLGINIKVMQTVGEGIKHNCPNAFVICITN 123 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++ +V L+K ++G+ LD R TFL D L + ++ Sbjct: 124 PLDIMV----NMLQKFSGVPDNKIVGMAGVLDSARFRTFLADELNVSVQQV--------- 170 Query: 178 HRKVTVIGGHSGETIIPIITDKSLV-----------FQLDKQYEHFIHRVQFGGDEIVKA 226 + V+GGH G+T++P+ ++ ++ + + R + GG EIV Sbjct: 171 --QAYVMGGH-GDTMVPLTKMSNVAGVSLEQLVKEGKLKQERLDAIVSRTRSGGGEIVAL 227 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286 + GSA + A AG + AE L+ P + A +Y G + Sbjct: 228 LK-TGSAYYAPAAAGIQMAESFLKDKKMILPCAAKVKAGMY--------------GLDED 272 Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 + +P + V I+ ++S +E + + ++ ++ + + Sbjct: 273 LFVGVPTEISANGVRPIE----VEISDKEREQLQVSINAIKDLNKAAAEIL 319 >2LDB-A nrPDB Length = 317 Score = 233 bits (595), Expect = 7e-62, Method: Composition-based stats. Identities = 72/341 (21%), Positives = 121/341 (35%), Gaps = 40/341 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE--GIGKDLSHINTNSSCVGYDKD 60 +V ++GA G VG L E+ L D ++ G D +H + Sbjct: 8 RVVVIGA-GFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPVDIWH 66 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + +A +V+I AG +KPG TR DL N I +S+V +V LV +NPV Sbjct: 67 GDYDDCRDADLVVICAGANQKPGETRLDLVDKNIAIFRSIVESVMASGFQGLFLVATNPV 126 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYL-----MLKNPKIGQEQDK 174 + L K V+G T LD R L +Y + IG+ D Sbjct: 127 DILTY----ATWKFSGLPHERVIGSGTILDTARFRFLLGEYFSVAPQNVHAYIIGEHGDT 182 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234 IG ++ S + K E V+ +I++ K G+ Sbjct: 183 ELPVWSQAYIGVMPIRKLVE-----SKGEEAQKDLERIFVNVRDAAYQIIEKK---GATY 234 Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294 +A A+ +L + E L+ YL GL + Y +P V Sbjct: 235 YGIAMGLARVTRAILHN------ENAILTVSAYLDGLYGERD----------VYIGVPAV 278 Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335 + + + +L+ E+ + + L+ + + + Sbjct: 279 INRNGIREVIEI---ELNDDEKNRFHHSAATLKSVLARAFT 316 >2LDX-A nrPDB Length = 331 Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats. Identities = 81/345 (23%), Positives = 148/345 (42%), Gaps = 45/345 (13%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYD--IRAAEGIGKDLSH--INTNSSCVGYD 58 K+ ++G G VG ++ + L ELAL D G DL H + ++ + + Sbjct: 21 KITVVGV-GDVGMACAISILLKGLADELALVDADTDKLRGEALDLQHGSLFLSTPKIVFG 79 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 KD N +N+++V+I AG G TR DL + N I+K++V V + +P+ +I+V++N Sbjct: 80 KD--YNVSANSKLVIITAGARMVSGQTRLDLLQRNVAIMKAIVPGVIQNSPDCKIIVVTN 137 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLML-----KNPKIGQEQ 172 PV+ L + + K+ F G V+G NLD R + + L + +G+ Sbjct: 138 PVDILTYV----VWKISGFPVGRVIGSGCNLDSARFRYLIGEKLGVNPTSCHGWVLGEHG 193 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAG 231 D + + G + +++ P ++ +KQ+ +H+ V GG E++ K G Sbjct: 194 DSSVPIWSGVNVAGVTLKSLNP-----AIGTDKNKQHWKNVHKQVVEGGYEVLDMK---G 245 Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291 + ++ + A +L++ P T + F G + S+ Sbjct: 246 YTSWAIGLSVTDLARSILKNLKRVHPVTTLVKGF---------------HGIKEEVFLSI 290 Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 P VL I V ++ EE L+ + L N++K Sbjct: 291 PCVLGESG---ITDFVKVNMTAEEEGLLKKSADTLW-NMQKNLEL 331 >1SOW-A nrPDB Length = 328 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 58/344 (16%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSC---VGYDK 59 K+A++G SG +G + L L ++ L+D+ GK L S V Sbjct: 10 KIAMIG-SGMIGGTMGYLCVLRELA-DVVLFDVVTGMPEGKALDDSQATSIADTNVSVTS 67 Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 + ++ + VV+I AG+ + PG +R+DL NA I++ + V K+ P A ++ Sbjct: 68 ANQYEKIAGSDVVIITAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKYCPLAFVI 127 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173 V++NP++ +V + + V G+ N LD R F+ D L + I Sbjct: 128 VVTNPLDCMV----KCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPRDI----- 178 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQ-----------LDKQYEHFIHRVQFGGDE 222 + TVIG H G+ ++P+ ++ + + + R + G E Sbjct: 179 ------QATVIGTH-GDHMLPLARYVTVNGFPLREFIKKGKMTEAKLAEIVERTKKAGGE 231 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 IV+ G GSA + A + A+ L+ P VY G Sbjct: 232 IVRLL-GQGSAYYAPALSAITMAQAFLKDEKRVLPC------SVYCQGEYGLHDM----- 279 Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKEL 326 + LP V+ G + + +L+ E++ +V ++ Sbjct: 280 -----FIGLPAVIGGGGIEQVIEL---ELTHEEQECFRKSVDDV 315 >1A5Z-A nrPDB Length = 319 Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats. Identities = 85/339 (25%), Positives = 134/339 (39%), Gaps = 45/339 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHI-NTNSSCVGYD 58 +K+ I+G G VG + L + + E+ L D+ AEG DL H Y Sbjct: 1 MKIGIVGL-GRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYA 59 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 D L + VV++ AGVP+KPG TR L NA ++K + V K+AP++ ++V++N Sbjct: 60 GD--YADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTN 117 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLM-----LKNPKIGQEQ 172 PV+ L + K P V G T LD R T + + + IG+ Sbjct: 118 PVDVLTYFFL----KESGMDPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHG 173 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQY-EHFIHRVQFGGDEIVKAKQGAG 231 D +IGG IP+ + + D + E+F + + EI++ K G Sbjct: 174 DSEVPVWSGAMIGG------IPLQNMCQVCQKCDSKILENFAEKTKRAAYEIIERK---G 224 Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291 + ++A A A E + E L+ VYL K S+ Sbjct: 225 ATHYAIALAVADIVESIFFD------EKRVLTLSVYLEDYLGVKDLC----------ISV 268 Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNI 330 P+ L V I L + + + L+ I Sbjct: 269 PVTLGKHGVERILELNLNEEE---LEAFRKSASILKNAI 304 >4M1Q-A nrPDB Length = 339 Score = 230 bits (585), Expect = 1e-60, Method: Composition-based stats. Identities = 75/343 (21%), Positives = 125/343 (36%), Gaps = 42/343 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSH-INTNSSCVGYDK 59 +V I+G +G VG + + E+ L D+ EG DL+H I + + Sbjct: 29 RVVIIG-TGAVGSSYAFSMINQNVTDEMVLIDLDKRKTEGDAMDLNHGIPFGAPTKVWAG 87 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 D +A +V+I AG +KPG TR DL + NA I K +V V N ++ +NP Sbjct: 88 D--YGDCKSADIVVITAGAAQKPGETRLDLVEKNANIFKGIVDQVMGSGFNGIFIIATNP 145 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYL-----MLKNPKIGQEQD 173 V+ L K V+G T LD R L +Y + +G+ D Sbjct: 146 VDVLAY----ATWKFSGLPKERVIGSGTILDTARFRFLLSEYFDIDVRNIHGYIMGEHGD 201 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233 T IG I DK +K + V+ I++ K G+ Sbjct: 202 TELPVWSQTRIGSEP----ISRYMDKYKPDGSNKDLDEIFVNVRDAAYHIIERK---GAT 254 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 ++A A+ + +LR+ E L+ + G D Y +P Sbjct: 255 HYAIAMGLARLTKAILRN------EQSILTVSTLMEGEY----------DLDDVYIGVPA 298 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 ++ V L+ E + ++ + L+ ++ Sbjct: 299 IVSQKGVERAIEI---DLNDEEMKKLHHSSNTLKDVMKPIFDM 338 >6J9S-A nrPDB Length = 326 Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats. Identities = 79/341 (23%), Positives = 129/341 (37%), Gaps = 43/341 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHI-NTNSSCVGYDK 59 KV ++G G VG + + L E+ + DI +G DL S Y Sbjct: 11 KVILVG-DGAVGSSYAYAMVLQGIAQEIGIVDIFKDKTKGDAIDLEDALPFTSPKKIYSA 69 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + + +A +V+I AG P+KPG TR DL N I+KS+V + N LV +NP Sbjct: 70 E--YSDAKDADLVVITAGAPQKPGETRLDLVNKNLKILKSIVDPIVDSGFNGIFLVAANP 127 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLV-----DYLMLKNPKIGQEQD 173 V+ L K+ F V+G T+LD R + D + +G+ D Sbjct: 128 VDILTY----ATWKLSGFPKNRVVGSGTSLDTARFRQSIAKMVNVDARSVHAYIMGEHGD 183 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233 IGG + + K+ + + V+ EI+K K G+ Sbjct: 184 TEFPVWSHANIGGVTIAEWV-----KAHPEIKEDKLVKMFEDVRNKAYEIIKLK---GAT 235 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 +A A A+ ++ +L E L VY+ G + Y P Sbjct: 236 FYGIATALARISKAILND------ENAVLPLSVYMDGQYG----------LNDIYIGTPA 279 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK 334 V+ + +I L+ EE+ + + +L+K + Sbjct: 280 VINRNGIQNILEI---PLTDHEEESMQKSASQLKKVLTDAF 317 >4BGV-A nrPDB Length = 323 Score = 226 bits (575), Expect = 1e-59, Method: Composition-based stats. Identities = 82/350 (23%), Positives = 148/350 (42%), Gaps = 51/350 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K++++GA G VG ++ L + ++ ++DI GK L I + GYD Sbjct: 4 KISVIGA-GAVGATVAQTLAIRQ-TGDIYIFDIVDGLAEGKALD-ILEGAPHWGYDLDIK 60 Query: 59 -----KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARI 113 +S + + V+++ AG+ RKPG++RDDL N GI+KS+ A+ K++P ++I Sbjct: 61 GFCTADESKYAEMKGSDVIVVTAGLARKPGMSRDDLLLKNIGIMKSVGEAIKKYSPESKI 120 Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQ 172 +V++NP + + K P ++G+ LD R TFL L + Sbjct: 121 VVVTNPADIMAYAIY----KASGISPERIIGLGGSLDSTRFRTFLAQELNV--------- 167 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKA 226 + VIGGH G+ ++P I ++ ++ + + R +FGG EIV Sbjct: 168 --SFEDVNAFVIGGH-GDDMVPFIRYSNVSGIPIEDLLPREKIDEIVKRTRFGGGEIVNL 224 Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286 + GSA + + A E ++ P Y+ G + + Sbjct: 225 YK-TGSAFYAPGISIAVMVESIVNDRKRVIPCA------AYITGEHSKTY------LVNN 271 Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 + +PI + V I K + E + +V+ ++KN + Sbjct: 272 LFIGVPIKIGKNGVEKIYDL---KFNEDELEAWKKSVESVKKNSAIADDY 318 >4Q3N-A nrPDB Length = 314 Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats. Identities = 78/325 (24%), Positives = 123/325 (37%), Gaps = 36/325 (11%) Query: 15 QPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVV 72 + + V EL L DI AEG DL+H K +A +V Sbjct: 16 MSYAYAMVNQGTVEELVLLDIDKRKAEGEAMDLNHGLAFGPRKMSIKAGDYKDCKDAGLV 75 Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132 +I AGV +K G TR L K NA I+K++V + N +LV SNPV+ L +A K Sbjct: 76 VITAGVNQKEGETRIHLLKRNAEIIKTVVKNIMSSGFNGILLVASNPVDVLAYVA---WK 132 Query: 133 KMGKFKPGNVMGVTNLDLVRAETFLVDYLM-----LKNPKIGQEQDKTTMHRKVTVIGGH 187 + G + T+LD R + Y+ + +G+ D + +G Sbjct: 133 ESGLHHSRVIGSGTSLDTARLRYEISQYIHIDSRNVHAYILGEHGDSEFVCWSNANVGAK 192 Query: 188 SGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEE 247 +I + + S + EH +V+ EI+ K+ + + A + Sbjct: 193 PIADVIDSMDEISF-----EDLEHIYLKVRDAAYEIISRKK---ATYYGIGMALVRITAA 244 Query: 248 VLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSV 307 + + + P L+ VY Y LP VL V I V Sbjct: 245 IFNNENRILP-ISVLNNGVY--------------DCEDQVYIGLPAVLNKDGVHHI---V 286 Query: 308 LEKLSPREEQLVNTAVKELRKNIEK 332 KL+ +E +N + LRKN++ Sbjct: 287 KLKLNEKENSQLNNSANILRKNLDD 311 >6H9S-A nrPDB Length = 307 Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats. Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 45/344 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDK 59 +K++I+G +G VG + L + E+ LYD+ AEG DL H T + Sbjct: 1 MKISIIG-TGRVGSSTAFALINAAVADEIVLYDLNKEMAEGEALDLLHATTFHKRMIIRA 59 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + + + +VLI AG +KPG TR DL NA I+K + + K+APN I+ I+NP Sbjct: 60 GEY-SDIEGSDIVLITAGAAQKPGETRLDLTIKNAKIIKGISENIKKYAPNTLIINITNP 118 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMG-VTNLDLVRAETFL-----VDYLMLKNPKIGQEQD 173 V+ + + + K+ F+ V+G T LD R + V + + IG+ D Sbjct: 119 VDVMSYV----VWKVTGFESNRVIGTGTILDTARLRALIGKNCGVSPMSVHAYIIGEHGD 174 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233 +IGG + + +K V+ I+ K G+ Sbjct: 175 SELAAWSSAMIGGVPIKG---FCRNCPYKDNCNKDLSKIFDDVKNSAYTIISKK---GAT 228 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 +A A E ++++ E + V L Y P Sbjct: 229 NYGIASATTALVESIIKN------EGRVYTPSVLLD----------------DVYIGYPA 266 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 V+ V + ++ L+ E + ++ +++ +E K+ + Sbjct: 267 VINKDGV---ERTIDITLNDEETEKFESSKSIIKEYLESIKNLL 307 >6CT6-A nrPDB Length = 338 Score = 223 bits (569), Expect = 7e-59, Method: Composition-based stats. Identities = 78/355 (21%), Positives = 147/355 (41%), Gaps = 48/355 (13%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSC---VGYDK 59 K+A++G SG +G ++ L L + ++ L+D+ +GK + + +S + Sbjct: 11 KIALVG-SGMIGGTMAFLCSLKE-LGDVVLFDVVPNMPMGKAMDLCHNSSVVDNGITVYG 68 Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 + L+NA VV+I AG+ + PG +R DL +N I++ + A+ K+ PNA I+ Sbjct: 69 SNSYECLTNADVVIITAGITKIPGKSDKEWSRMDLLPVNIKIMREVGGAIKKYCPNAFII 128 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168 I+NP++ +V +++ + G+ LD R + D L + I Sbjct: 129 NITNPLDVMV----AAVQEAANVPKHMICGMAGMLDSSRLRRMIADCLHVSPHDVQGMVI 184 Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228 G D + I G IPI + + + ++ + G +IV+ Sbjct: 185 GVHGDNMLPLMRYITING------IPIQEFINKGLINKEDINNIYNKTKQAGGDIVRLL- 237 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 G GSA + + AE L+ + YL G N Y Sbjct: 238 GQGSAYYAPGTSAILMAESYLKDKKR------LFVSSCYLNGQYNVNN----------HY 281 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 343 +P ++ + I L+ E++L+ ++ E+ + ++K + LD+ KL Sbjct: 282 LGVPCIIGGKGIEQIIEL---DLNQEEKKLLQGSIDEVLE-MQKAIA-ALDAGKL 331 >1UXJ-A nrPDB Length = 309 Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 89/345 (25%), Positives = 152/345 (44%), Gaps = 50/345 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58 K++I+GA G VG + L + ++ L DI GK L + S G+D Sbjct: 4 KISIIGA-GFVGSTTAHWLAAKE-LGDIVLLDIVEGVPQGKALD-LYEASPIEGFDVRVT 60 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + +N+ V+++ +G PRKPG++R+DL K+NA I ++ ++ +PNA I++++N Sbjct: 61 GTNNYADTANSDVIVVTSGAPRKPGMSREDLIKVNADITRACISQAAPLSPNAVIIMVNN 120 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++++ +A E F V+G LD R TF+ E + Sbjct: 121 PLDAMTYLAAEV----SGFPKERVIGQAGVLDAARYRTFIA-----------MEAGVSVK 165 Query: 178 HRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231 + ++GGH G+ ++P+ ++ F + + R + GG EIV + G Sbjct: 166 DVQAMLMGGH-GDEMVPLPRFSTISGIPVSEFIAPDRLAQIVERTRKGGGEIVNLLK-TG 223 Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291 SA + A A A+ E VL+ P YL G + YF + Sbjct: 224 SAYYAPAAATAQMVEAVLKDKKRVMPVA------AYLTGQYG----------LNDIYFGV 267 Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 P++L G V I L+ E L+N + K +R ++ KS Sbjct: 268 PVILGAGGVEKILEL---PLNEEEMALLNASAKAVRATLDTLKSL 309 >3NEP-X nrPDB Length = 314 Score = 218 bits (554), Expect = 4e-57, Method: Composition-based stats. Identities = 78/346 (22%), Positives = 141/346 (40%), Gaps = 50/346 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD--- 58 +KV ++GA G VG ++ + E+ + DI+ GK L + +S G+D Sbjct: 1 MKVTVIGA-GNVGATVAECVARQDVAKEVVMVDIKDGMPQGKALD-MRESSPIHGFDTRV 58 Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 + ++ V +I AG+PR PG++RDDL N IV + + +P++ I+V++ Sbjct: 59 TGTNDYGPTEDSDVCIITAGLPRSPGMSRDDLLAKNTEIVGGVTEQFVEGSPDSTIIVVA 118 Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 NP++ + +A E F VMG+ LD R +F+ + L D + Sbjct: 119 NPLDVMTYVAYE----ASGFPTNRVMGMAGVLDTGRFRSFIAEEL-----------DVSV 163 Query: 177 MHRKVTVIGGHSGETIIPIITDKSLVFQL------DKQYEHFIHRVQFGGDEIVKAKQGA 230 + ++GGH G+T++P+ ++ D + E + R + G EIV Sbjct: 164 RDVQALLMGGH-GDTMVPLPRYTTVGGIPVPQLIDDARIEEIVERTKGAGGEIVDL--MG 220 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290 SA + A A+ E +L+ P Y G + Sbjct: 221 TSAWYAPGAAAAEMTEAILKDNKRILPCA------AYCDGEYG----------LDDLFIG 264 Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 +P+ L G V + L E+ + T+ + N++ + Sbjct: 265 VPVKLGAGGVEEVIEV---DLDADEKAQLKTSAGHVHSNLDDLQRL 307 >1Y6J-A nrPDB Length = 318 Score = 217 bits (553), Expect = 5e-57, Method: Composition-based stats. Identities = 77/342 (22%), Positives = 138/342 (40%), Gaps = 40/342 (11%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE--GIGKDLSHINTNSSCVGYDKD 60 KVAI+GA G VG + + L +EL L D+ + G D++H + Sbjct: 9 KVAIIGA-GFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAG 67 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + + + V+++ AG RKPG TR DL K N I K + + K+ + ILV+SNPV Sbjct: 68 DY-SDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPV 126 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLM-----LKNPKIGQEQDK 174 + + ++K G V+G T LD +R L + L + IG+ D Sbjct: 127 DIITY----MIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNVHGYIIGEHGDS 182 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234 T I G + I D ++ + V+ G I+K K G+ Sbjct: 183 QLPLWSCTHIAGKNINEYI----DDPKCNFTEEDKKKIAEDVKTAGATIIKNK---GATY 235 Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294 +A + E +L++ + + ++ + SLP + Sbjct: 236 YGIAVSINTIVETLLKNQNTIRTVGTVINGMYGIE----------------DVAISLPSI 279 Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 + + V + L+P EE+ + + ++++K + + K+ Sbjct: 280 VNSEGVQEVLQF---NLTPEEEEALRFSAEQVKKVLNEVKNL 318 >3WSV-A nrPDB Length = 322 Score = 214 bits (545), Expect = 5e-56, Method: Composition-based stats. Identities = 73/339 (21%), Positives = 131/339 (38%), Gaps = 42/339 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSH---INTNSSCVGYDK 59 KV I+G +G VG ++ + +EL L D+ + G+ L + V Sbjct: 7 KVVIVG-TGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNVSVWS 65 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + E +A +V++ AGV +KPG TR DL K NA I + +V V + +V SNP Sbjct: 66 GTYEE-CQDANLVILTAGVNQKPGQTRLDLVKTNATITRQIVKEVMASGFDGIFVVASNP 124 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLV-----DYLMLKNPKIGQEQDK 174 V+ L + T ++ G V T LD R + D + +G+ D Sbjct: 125 VDILTYL---TWQESGLPASRVVGTGTTLDTTRFRKEIALKLAVDPRSVHGYILGEHGDS 181 Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDK-QYEHFIHRVQFGGDEIVKAKQGAGSA 233 T +GG PI+ +L++ +V+ EI+ K+ + Sbjct: 182 EVAAWSHTTVGGK------PIMEYVEKDHRLEENDLTVLADKVKNAAYEIIDRKK---AT 232 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 + + + + +L + E L YL G + +P Sbjct: 233 YYGIGMSTTRIVKAILNN------EQAVLPVSAYLNGEYG----------EEDIFTGVPS 276 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEK 332 ++ V I + +P+E+ + + +V EL+ ++ Sbjct: 277 IVDENGVREIIDLSI---TPQEKAMFHQSVSELKAVLDT 312 >1EZ4-A nrPDB Length = 318 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 71/341 (20%), Positives = 116/341 (34%), Gaps = 44/341 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHI-NTNSSCVGYDK 59 KV ++G G VG + + E + D+ +G DL + Y Sbjct: 7 KVVLVG-DGAVGSSYAFAMAQQGIAEEFVIVDVVKDRTKGDALDLEDAQAFTAPKKIYSG 65 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + + +A +V+I AG P+KPG +R DL N I+ S+V V + LV +NP Sbjct: 66 E--YSDCKDADLVVITAGAPQKPGESRLDLVNKNLNILSSIVKPVVDSGFDGIFLVAANP 123 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKI-----GQEQD 173 V+ L K F V+G T+LD R L + + G+ D Sbjct: 124 VDILTY----ATWKFSGFPKERVIGSGTSLDSSRLRVALGKQFNVDPRSVDAYIMGEHGD 179 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233 IG P+ D V+ +I+ K G+ Sbjct: 180 SEFAAYSTATIGT------RPVRDVAKEQGVSDDDLAKLEDGVRNKAYDIINLK---GAT 230 Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293 + A + ++ +LR E L Y+ G + Y P Sbjct: 231 FYGIGTALMRISKAILRD------ENAVLPVGAYMDGQYG----------LNDIYIGTPA 274 Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK 334 ++ + I S LS E + + + L+K + G Sbjct: 275 IIGGTGLKQIIES---PLSADELKKMQDSAATLKKVLNDGL 312 >3ZZN-A nrPDB Length = 310 Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats. Identities = 78/337 (23%), Positives = 127/337 (37%), Gaps = 44/337 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDK 59 +KV I+G SG VG + L L E+ L D+ A+ +D+ H + V Sbjct: 1 MKVGIVG-SGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWA 59 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 S L A+ V++ AGV ++PG TR L NA + +V V + AP A +LV +NP Sbjct: 60 GSY-GDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNP 118 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYL-----MLKNPKIGQEQD 173 V+ + +A + PG V+G T LD R L +YL + +G+ D Sbjct: 119 VDVMTQVAYA----LSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGD 174 Query: 174 KTTMHRKVTVIGGHSGETIIPI--ITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231 + +GG +P+ + + V+ I++ K G Sbjct: 175 SEVLVWSSAQVGG------VPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGK---G 225 Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291 + + A+ +L G+ V SL Sbjct: 226 ATYYGIGAGLARLVRAILTDEK----------------GVYTVSAFTPEVAGVLEVSLSL 269 Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRK 328 P +L G V +V LSP E + + + L++ Sbjct: 270 PRILGAGGVA---GTVYPSLSPEERAALRRSAEILKE 303 >5MDH-A nrPDB Length = 333 Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats. Identities = 75/358 (20%), Positives = 130/358 (36%), Gaps = 53/358 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDIRAAEGIG----KDLSHINTNS 52 ++V + GA+G + L + + L L DI G+ +L Sbjct: 4 IRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPL 63 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA- 111 D E + V ++ +PR+ G+ R DL K N I K A+ K+A + Sbjct: 64 LKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSV 123 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171 +++V+ NP N+ A K N +T LD RA+ + L + + + Sbjct: 124 KVIVVGNPANTNCLTAS---KSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDV--- 177 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDK------------QYEHFIHRVQFG 219 + V + G HS T P + + Q + FI VQ Sbjct: 178 -------KNVIIWGNHS-STQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQR 229 Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQ 279 G ++KA++ LS A + AK + +R PE E +S + G G Sbjct: 230 GAAVIKARK------LSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYG----- 278 Query: 280 LVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 +S P+ +++ + ++ + S + L KEL + E F+ Sbjct: 279 ---VPDDLLYSFPVTIKDKTWKIVEGLPINDFSREKMDL---TAKELAEEKETAFEFL 330 >4UUP-A nrPDB Length = 341 Score = 201 bits (511), Expect = 4e-52, Method: Composition-based stats. Identities = 78/349 (22%), Positives = 137/349 (39%), Gaps = 48/349 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE----LALYDI----RAAEGIGKDLSHINTNSS 53 + V I GA+G +G L+ + + L L +I +A EG+ +L + Sbjct: 5 IHVLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTL 64 Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNAR 112 D E + V + PRKPG+ R DL + NAGI K A+ ++A P + Sbjct: 65 AGVVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVK 124 Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172 +LV+ NP N+ IA+ K+G P N +T LD RA + L + K+ Sbjct: 125 VLVVGNPANTNCLIAMANAPKLG---PENFSAMTRLDHNRAIGEIAAKLGVPVDKV---- 177 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITD---------KSLVFQLDKQY--EHFIHRVQFGGD 221 V V G HS T +P ++ K + L K+Y F+ ++ G Sbjct: 178 ------HNVVVWGNHS-NTQVPDVSHATVDKEGGTKKVSDALPKEYLEGEFVQKIAQRGG 230 Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281 +++A+ + A + A A +R + + +S + +P Sbjct: 231 AVIEARGAS------SAASAANAALCHMRDWLFGTKPGDWVSMGIPVP-------EGNPY 277 Query: 282 GDNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKN 329 G +S P + ++G V ++ + + + + E R+ Sbjct: 278 GIKPGVIYSFPCTVDKDGKVHIVEGLEINDWVREKMEATEKELIEERET 326 >1PZF-A nrPDB Length = 331 Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats. Identities = 75/322 (23%), Positives = 131/322 (40%), Gaps = 56/322 (17%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINT--NSSCVGYD 58 KVA++G SG +G + L L ++ LYD+ EG DLSH+ + +++ Sbjct: 11 KVAMIG-SGMIGGTMGYLCALRELA-DVVLYDVVKGMPEGKALDLSHVTSVVDTNVSVRA 68 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARI 113 + S E L+ A V++ AG+ + PG +R+DL N+ I++ + + K+ P I Sbjct: 69 EYSYEAALTGADCVIVTAGLTKVPGKPDSEWSRNDLLPFNSKIIREIGQNIKKYCPKTFI 128 Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQ 172 +V++NP++ +V + E + G+ LD R ++ D L + + Sbjct: 129 IVVTNPLDCMVKVMCE----ASGVPTNMICGMACMLDSGRFRRYVADALSVSPRDV---- 180 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVF-----------QLDKQYEHFIHRVQFGGD 221 + TVIG H G+ ++P++ ++ +KQ E + G Sbjct: 181 -------QATVIGTH-GDCMVPLVRYITVNGYPIQKFIKDGVVTEKQLEEIAEHTKVSGG 232 Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281 EIV+ G GSA + A + A L P VY G K Sbjct: 233 EIVRFL-GQGSAYYAPAASAVAMATSFLNDEKRVIPC------SVYCNGEYGLKDM---- 281 Query: 282 GDNSIEYFSLPIVLRNGSVVSI 303 + LP V+ + + Sbjct: 282 ------FIGLPAVIGGAGIERV 297 >1T24-A nrPDB Length = 322 Score = 196 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 74/340 (21%), Positives = 134/340 (39%), Gaps = 48/340 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG---YDK 59 K+ ++G SG +G ++ L+ + + ++ L+DI GK L +TN Sbjct: 6 KIVLVG-SGMIGGVMATLI-VQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSG 63 Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 + + L+ A VV++ AG + PG RDDL +N I+ + + K PNA I+ Sbjct: 64 SNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFII 123 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168 V++NPV+ +V + L + ++G+ LD R + ++ L + + Sbjct: 124 VVTNPVDVMVQL----LHQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNAHIV 179 Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228 G +K + ++ +GG IP+ + D + E R EIV Sbjct: 180 GAHGNKMVLLKRYITVGG------IPLQEFINNKLISDAELEAIFDRTVNTALEIVNLHA 233 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 S ++ A A + AE L+ L L G S + Sbjct: 234 ---SPYVAPAAAIIEMAESYLKDLKKV------LICSTLLEGQYGH----------SDIF 274 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRK 328 P+VL V + +L+ E+ + A+ E ++ Sbjct: 275 GGTPVVLGANGVEQVIEL---QLNSEEKAKFDEAIAETKR 311 >3LDH-A nrPDB Length = 330 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 67/354 (18%), Positives = 125/354 (35%), Gaps = 66/354 (18%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60 K+ ++G VG ++ + + E+AL D+ +G DL H + Sbjct: 23 KITVVGCD-AVGMADAISVLMKDLADEVALVDVMEDKLKGEMMDLEHGSLFLHTAKIVSG 81 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 + + +++V+I AG ++ G +R +L + N I K ++ + K +P+ L +P Sbjct: 82 KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDC--LKELHP- 138 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 L + K+ ++G NLD R + + L + + Sbjct: 139 -ELGTDKNKQDWKLSGLPMHRIIGSGCNLDSARFRYLMGERLGVH-----------SCLV 186 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 VIG H G+++ + + V E++K K G + ++ Sbjct: 187 IGWVIGQH-GDSVPSVWSGMW--------DAKLHKDVVDSAYEVIKLK---GYTSWAIGL 234 Query: 240 -----------------AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 + A A+ +++ P + + F G Sbjct: 235 VVSNPVDVLTYVAWKGCSVADLAQTIMKDLCRVHPVSTMVKDF---------------YG 279 Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 + SLP VL NG V KL P EEQ + + L +I+K F Sbjct: 280 IKDNVFLSLPCVLNNGISHCN--IVKMKLKPDEEQQLQKSATTLW-DIQKDLKF 330 >5NFR-A nrPDB Length = 320 Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats. Identities = 79/353 (22%), Positives = 146/353 (41%), Gaps = 57/353 (16%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINT--NSSCVG 56 M K+A++G SG +G + L L + +L LYD+ +G DL H +T + Sbjct: 1 MTKIALIG-SGQIGAIVGELCLL-ENLGDLILYDVVPGIPQGKALDLKHFSTILGVNRNI 58 Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + IE+ + +A +++I AGV RK G+TR+DL +N I+KS+ +V A ++ + Sbjct: 59 LGTNQIED-IKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVICV 117 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175 SNP++ +V + K + G+ LD R + + D L + + Sbjct: 118 SNPLDIMVNV----FHKFSNLPHEKICGMAGILDTSRYCSLIADKLKVSAEDV------- 166 Query: 176 TMHRKVTVIGGHSGETIIPIITDKSLVF-----------QLDKQYEHFIHRVQFGGDEIV 224 ++GGH G+ ++P+ S+ + + I + + G EI+ Sbjct: 167 ----NAVILGGH-GDLMVPLQRYTSVNGVPLSEFVKKNMISQNEIQEIIQKTRNMGAEII 221 Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284 K + + A + A A K + L + +N + VYL G N Sbjct: 222 KLAKAS--AAFAPAAAITKMIKSYLYNENN------LFTCAVYLNGHYN----------C 263 Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 S + + N ++ L+ E+ L ++ ++ N +K I Sbjct: 264 SNLFVGSTAKINNKGAHPVEF----PLTKEEQDLYTESIASVQSNTQKAFDLI 312 >5HTO-A nrPDB Length = 346 Score = 193 bits (490), Expect = 1e-49, Method: Composition-based stats. Identities = 69/340 (20%), Positives = 131/340 (38%), Gaps = 48/340 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG---YDK 59 K+ ++G SG +G ++ L+ + + ++ ++D+ GK L ++N Sbjct: 36 KIVLVG-SGMIGGVMATLI-VQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTG 93 Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 + + L A VV++ AG + PG RDDL +N I+ + + PNA I+ Sbjct: 94 SNSYDDLKGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFII 153 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168 V++NPV+ +V + E ++G+ LD R + ++ L + + Sbjct: 154 VVTNPVDVMVQLLFEH----SGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIV 209 Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228 G +K + ++ +GG IP+ + D++ E R EIV Sbjct: 210 GAHGNKMVLLKRYITVGG------IPLQEFINNKKITDEEVEGIFDRTVNTALEIVNLLA 263 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 S ++ A A + AE L+ L L G + Sbjct: 264 ---SPYVAPAAAIIEMAESYLKDIKKV------LVCSTLLEGQYGHSN----------IF 304 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRK 328 P+V+ V + +L+ E+ + AV E ++ Sbjct: 305 GGTPLVIGGTGVEQVIEL---QLNAEEKTKFDEAVAETKR 341 >1HYE-A nrPDB Length = 313 Score = 193 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 88/348 (25%), Positives = 148/348 (42%), Gaps = 48/348 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALY----DIRAAEGIGKDL--SHINTNSSCV 55 +KV I+GASG VG +LLL P++ +L L I EG+ +D+ + T S Sbjct: 1 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60 Query: 56 GY-DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 Y + D + + VV+I +GVPRK G++R DL K NA IV + + + +I Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEIC-DTKIF 119 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLK-----NPKI 168 VI+NPV+ + A+ KF+ V G+ T+LD +R + + + + I Sbjct: 120 VITNPVDVMTYKALVD----SKFERNQVFGLGTHLDSLRFKVAIAKFFGVHIDEVRTRII 175 Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228 G+ D T IGG IPI + + I V+ G++I++ K Sbjct: 176 GEHGDSMVPLLSATSIGG------IPIQKFERFKELP---IDEIIEDVKTKGEQIIRLKG 226 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 G+ F A V+R N + +LSA Y+ G +G Sbjct: 227 GS-------EFGPAAAILNVVRCIVNNEKRLLTLSA--YVDGEFDG---------IRDVC 268 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336 +P+ + + + + +L E + + ++K E+ K+ Sbjct: 269 IGVPVKIGRDGIEEVVSI---ELDKDEIIAFRKSAEIIKKYCEEVKNL 313 >1OC4-A nrPDB Length = 322 Score = 193 bits (489), Expect = 1e-49, Method: Composition-based stats. Identities = 71/337 (21%), Positives = 133/337 (39%), Gaps = 48/337 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG---YDK 59 K+ ++G SG +G ++ L+ + + ++ ++DI GK L +TN Sbjct: 6 KIVLVG-SGMIGGVMATLI-VQKNLGDVVMFDIVKNMPHGKALDTSHTNVMAYSNCKVSG 63 Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114 + + L +A VV++ AG + PG RDDL +N I+ + + PNA I+ Sbjct: 64 SNTYDDLKDADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNNCPNAFII 123 Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168 V++NPV+ +V + L + ++G+ LD R + ++ L + + Sbjct: 124 VVTNPVDVMVQL----LHQHSGVPKNKIVGLGGVLDTSRLKYYISQKLNVCPRDVNAHIV 179 Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228 G +K + ++ +GG IP+ + D++ + R EIV Sbjct: 180 GAHGNKMVLLKRYITVGG------IPLQEFINNKKITDQELDAIFDRTINTALEIVNLHA 233 Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288 S ++ A A + AE +R L L G K + Sbjct: 234 ---SPYVAPAAAIIEMAESYIRDLRKV------LICSTLLEGQYGHKD----------IF 274 Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKE 325 P+V+ V + +L+ E++ + AV E Sbjct: 275 AGTPLVIGGNGVEQVIEL---QLNADEKKKFDEAVAE 308 >5NUE-A nrPDB Length = 332 Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats. Identities = 77/356 (21%), Positives = 134/356 (37%), Gaps = 54/356 (15%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDIR----AAEGIGKDLSHINTNS 52 V+V + GA+G +G L ++ + L + DI A G+ +L Sbjct: 6 VRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPL 65 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKF-APNA 111 + V ++ G PRK G+ R D+ N I KS A+ K APN Sbjct: 66 LKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNC 125 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171 ++LV++NP N+ I E N+ +T LD RA + + L + + Sbjct: 126 KVLVVANPANTNALILKE---FAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDV--- 179 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQ------------YEHFIHRVQFG 219 + V + G HS + P + + ++ FI VQ Sbjct: 180 -------KNVIIWGNHS-SSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQR 231 Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQ 279 G I+KA++ + A + A A + +R + PE +S VY G + Sbjct: 232 GAAIIKARKLS------SALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGL- 284 Query: 280 LVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335 +S P+ RNG + ++++S ++ L +EL++ + S Sbjct: 285 --------IYSFPVTCRNGDWSIVQGLPIDEVSRKKMDL---TAEELKEEKDLAYS 329 >2V6B-A nrPDB Length = 304 Score = 190 bits (482), Expect = 9e-49, Method: Composition-based stats. Identities = 68/321 (21%), Positives = 118/321 (36%), Gaps = 33/321 (10%) Query: 15 QPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVV 72 + L L SEL L D A+ +D++H S + L++AQVV Sbjct: 13 STAAFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVW-HGGHSELADAQVV 71 Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132 ++ AG +KPG +R DL + NA I + LV + + AP+A +LV SNPV+ L +A + Sbjct: 72 ILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVDLLTDLATQLAP 131 Query: 133 KMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETI 192 G V+ + A+ VD +G+ D + ++ G Sbjct: 132 GQPVIGSGTVLDSARFRHLMAQHAGVDGTHAHGYVLGEHGDSEVLAWSSAMVAGMP---- 187 Query: 193 IPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSF 252 + + ++ + I++ K+ + + A A+ E VLR Sbjct: 188 VADFMQAQNLPWNEQVRAKIDEGTRNAAASIIEGKR---ATYYGIGAALARITEAVLRDR 244 Query: 253 HNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLS 312 + + SLP V+ V+S KL+ Sbjct: 245 RAVLTVSAPTPEY--------------------GVSLSLPRVVGRQGVLSTLHP---KLT 281 Query: 313 PREEQLVNTAVKELRKNIEKG 333 E+Q + + LR ++ Sbjct: 282 GDEQQKLEQSAGVLRGFKQQL 302 >4ND4-A nrPDB Length = 321 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 71/335 (21%), Positives = 137/335 (40%), Gaps = 43/335 (12%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSH--INTNSSCVGYD 58 K+A++G SG +G ++ + ++++ L+DI +G D++H + S+ Sbjct: 6 KIAVIG-SGQIGGNIAY-IVGKDNLADVVLFDIAEGIPQGKALDITHSMVMFGSTSKVIG 63 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + + +S + VV+I A +P +P R +L NA I+ S+ V K+ PNA ++ I+N Sbjct: 64 TNDYAD-ISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKYCPNAFVICITN 122 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----IGQEQ 172 P++ +V +K+ V G+ LD R TF+ + + IG Sbjct: 123 PLDVMV----SHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQHFGVNASDVSANVIGGHG 178 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232 D +GG +P+ + +Q + + + E+ + G+ Sbjct: 179 DGMVPATSSVSVGG------VPLSSFIKQGLITQEQIDEIVCHTRIAWKEVADNLK-TGT 231 Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292 A + A A K AE L+ P + S + G+ Y +P Sbjct: 232 AYFAPAAAAVKMAEAYLKDKKAVVPCSAFCSNHYGVKGI----------------YMGVP 275 Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELR 327 ++ V I L+P E++L+ ++ E+ Sbjct: 276 TIIGKNGVEDILEL---DLTPLEQKLLGESINEVN 307 >3FI9-A nrPDB Length = 343 Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats. Identities = 65/332 (19%), Positives = 126/332 (37%), Gaps = 29/332 (8%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKD 60 K+ I+GA+G +G ++ + L LYD A EG+ +++ H + + D Sbjct: 10 KLTIVGAAGMIGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGLNLTFTSD 69 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNAR-ILVISNP 119 I+ L++A+ ++ G PRK G+TR+DL K NA I L + + P+ + +++I NP Sbjct: 70 -IKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNP 128 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 + + + KP V + LD R ++ L + +K + + Sbjct: 129 ADITGLVTLIY----SGLKPSQVTTLAGLDSTRLQSELAKHFGIKQSLVTNTRTYGGHGE 184 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239 ++ V + P+ ++Q+ RV GG I+K + S+ S ++ Sbjct: 185 QMAVFASTAKVNGTPLTDLIGTDKLTNEQWAELKQRVVKGGANIIKLRGR--SSFQSPSY 242 Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299 + + E A Y+ V ++ + Sbjct: 243 VSIEMIRAAMG------GEAFRWPAGCYVN-----------VPGFEHIMMAMETTITKDG 285 Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331 V D + L + E + + L K + Sbjct: 286 VKHSDINQLG--NEAERAALKESYSHLAKLRD 315 >4I1I-A nrPDB Length = 345 Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats. Identities = 82/345 (23%), Positives = 135/345 (39%), Gaps = 47/345 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVS-----ELALYDI----RAAEGIGKDLSHINTNS 52 VKVA+ GA+G +G L L+ + EL L DI +A G+ +L Sbjct: 25 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 84 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKF-APNA 111 + ++ PRK G+ R DL +MNA I K A+ A + Sbjct: 85 LDKVVVTADPRVAFDGVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEAIAAVAASDC 144 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171 R++V+ NP N+ I +++ + GK P +V +T LD RA + L + ++ Sbjct: 145 RVVVVGNPANTNALILLKSAQ--GKLNPRHVTAMTRLDHNRALSLLARKAGVPVSQV--- 199 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSL-------VFQLDKQYEHFIHRVQFGGDEIV 224 R V + G HS T +P + + D + F+ V+ G EI+ Sbjct: 200 -------RNVIIWGNHS-STQVPDTDSAVIGTTPAREAIKDDALDDDFVQVVRGRGAEII 251 Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284 + + LS A + AK A + + + + PE +S VY G Sbjct: 252 QLRG------LSSAMSAAKAAVDHVHDWIHGTPEGVYVSMGVYSDENPYG--------VP 297 Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKN 329 S FS P G + + L +Q + + + EL++ Sbjct: 298 SGLIFSFPCTCHAGEWTVVSGKLNGDLG---KQRLASTIAELQEE 339 >2D4A-B nrPDB Length = 308 Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats. Identities = 66/338 (19%), Positives = 127/338 (37%), Gaps = 45/338 (13%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVG-YDKDS 61 + ILGA G VG +++L + Y L + +G DL+H + Sbjct: 2 ITILGA-GKVGMATAVMLMMRGYDDLLLIARTPGKPQGEALDLAHAAAELGVDIRISGSN 60 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 + + +VL+ AG+ RKPG+TR+ L + NA + L + +A +A +++ +NPV+ Sbjct: 61 SYEDMRGSDIVLVTAGIGRKPGMTREQLLEANANTMADLAEKIKAYAKDAIVVITTNPVD 120 Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLK-----NPKIGQEQDKT 175 ++ + K F V+G + LD R ++ L + +G K Sbjct: 121 AMTYVMY----KKTGFPRERVIGFSGILDSARMAYYISQKLGVSFKSVNAIVLGMHGQKM 176 Query: 176 TMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATL 235 +++ +GG E ++ ++ E + G +I + + S+ Sbjct: 177 FPVPRLSSVGGVPLEHLM-----------SKEEIEEVVSETVNAGAKITELRGY--SSNY 223 Query: 236 SMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL 295 A E + R P +YL G +P V+ Sbjct: 224 GPAAGLVLTVEAIKRDSKRIYPY------SLYLQGEYGYNDIVAE----------VPAVI 267 Query: 296 RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKG 333 + I L+ E++ + AV+ ++K +E Sbjct: 268 GKSGIERIIEL---PLTEDEKRKFDEAVQAVKKLVETL 302 >4UUO-A nrPDB Length = 340 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 75/356 (21%), Positives = 129/356 (36%), Gaps = 49/356 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE----LALYDI----RAAEGIGKDLSHINTNSS 53 + + I GA+G +G L+ + + L L +I +A EG +L + Sbjct: 4 IHILITGAAGQIGYALTFRIAKGDLCGDRKVVLHLLEIPFGMKALEGCVMELQDCAFPNV 63 Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNAR 112 D +E V + PRK G+ R DL N GI A+ +A P + Sbjct: 64 AGIVWTDKVEEAFKGVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALNDYAKPTVK 123 Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172 +LV+ NP N+ IA + K+ + N +T LD R L + KI Sbjct: 124 VLVVGNPANTNCLIAQASAPKL---QNKNWCAMTRLDHNRMVGALAAKFGVTPEKI---- 176 Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKS---------LVFQLDKQY--EHFIHRVQFGGD 221 KV + G HS T +P T + + +L K+Y F + G Sbjct: 177 ------HKVCIWGNHS-NTQVPDTTHATVDLPEGTVKVADKLPKEYLEGEFAQMIATRGG 229 Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281 ++K + + A + A A ++ + E + +S + +P + Sbjct: 230 AVIKMRGAS------SAASAANAALTCVKDWLYGTAEGDFVSMAIPVPDN-------EPY 276 Query: 282 GDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337 G FS P+ + V + + +L+ + + KEL E + Sbjct: 277 GIKQGTIFSFPVTVSKDGEVHVVEGL--ELNDWVKGRLEATEKELIGEKETAWKVL 330 >2X0J-A nrPDB Length = 294 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 80/336 (23%), Positives = 137/336 (40%), Gaps = 48/336 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTN-SSCVGYD 58 +K+ +GA G VG + L+ V E+AL DI A G DL+H Sbjct: 1 MKLGFVGA-GRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIV 59 Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 + + L ++++++ AG+ RKPG+TR DL NAGI+K + + + AP ++ILV++N Sbjct: 60 GGADYSLLKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTN 119 Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177 P++ + I K V G+ N LD R + L + Sbjct: 120 PMDVMTYIM----WKESGKPRNEVFGMGNQLDSQRLKERLYNA-------------GARN 162 Query: 178 HRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSM 237 R+ +IG H G+++ + F + +E + V+F E++K K G+ Sbjct: 163 IRRAWIIGEH-GDSM--FVAKSLADFDGEVDWEAVENDVRFVAAEVIKRK---GATIFGP 216 Query: 238 AFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRN 297 A A + + V+ E + + L G + +P L Sbjct: 217 AVAIYRMVKAVVEDT------GEIIPTSMILQGEYGIENVA----------VGVPAKLGK 260 Query: 298 GSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKG 333 D KLS E + + + K LR+ +E+ Sbjct: 261 NGAEVADI----KLSDEEIEKLRNSAKILRERLEEL 292 >4KDE-A nrPDB Length = 341 Score = 183 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 79/354 (22%), Positives = 141/354 (39%), Gaps = 49/354 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDI----RAAEGIGKDLSHINTNS 52 V+VA+ GA+G +G L + + + L L +I +A EG+ +L Sbjct: 5 VRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEIPQAMKALEGVVMELEDCAFPL 64 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNA 111 D + +A L+ PRK G+ R DL ++N I A+ + A + Sbjct: 65 LAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKKDV 124 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171 ++LV+ NP N+ IA K P N +T LD RA+ L +I Sbjct: 125 KVLVVGNPANTNALIAY---KNAPGLNPRNFTAMTRLDHNRAKAQLAKKTGTGVDRI--- 178 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQL-----DKQYEH--FIHRVQFGGDEIV 224 R++TV G HS T+ P + + + D ++ FI V G I+ Sbjct: 179 -------RRMTVWGNHS-STMFPDLFHAEVDGRPALELVDMEWYEKVFIPTVAQRGAAII 230 Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284 +A+ + A + A A E +R + PE + +S V G + Sbjct: 231 QARGAS------SAASAANAAIEHIRDWALGTPEGDWVSMAVPSQGEYGIPEGIV----- 279 Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338 +S P+ ++G+ ++ + + + + ++ +EL +E+ K+ L Sbjct: 280 ----YSFPVTAKDGAYRVVEGLEINEFARKRMEI---TAQELLDEMEQVKALGL 326 >7MDH-A nrPDB Length = 375 Score = 179 bits (453), Expect = 2e-45, Method: Composition-based stats. Identities = 77/345 (22%), Positives = 123/345 (35%), Gaps = 52/345 (15%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSE-----LALY----DIRAAEGIGKDLSHINTN 51 +V +A+ GA+G + L L + L L +A EG+ +L Sbjct: 32 LVNIAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYP 91 Query: 52 SSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PN 110 + L+ PR PG+ R L +N I A+ A N Sbjct: 92 LLREVSIGIDPYEVFEDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASKN 151 Query: 111 ARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQ 170 ++LV+ NP N+ I LK N +T LD RA+ L K G Sbjct: 152 VKVLVVGNPCNTNALI---CLKNAPDIPAKNFHALTRLDENRAKCQLA-------LKAGV 201 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITD--------KSLVFQLDKQYEHFIHRVQFGGDE 222 DK + VT+ G HS T +P + K ++ + E F VQ G Sbjct: 202 FYDKVS---NVTIWGNHS-TTQVPDFLNAKIDGRPVKEVIKRTKWLEEEFTITVQKRGGA 257 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 +++ + +A+ +++ A A ++S PE + S VY G G Sbjct: 258 LIQKWGRSSAASTAVSIADA------IKSLVTPTPEGDWFSTGVYTTGNPYG-------- 303 Query: 283 DNSIEYFSLPIVLRNGS------VVSIDTSVLEKLSPREEQLVNT 321 FS+P + VS D + E++ E +L+ Sbjct: 304 IAEDIVFSMPCRSKGDGDYELATDVSNDDFLWERIKKSEAELLAE 348 >1CIV-A nrPDB Length = 385 Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats. Identities = 78/345 (22%), Positives = 124/345 (35%), Gaps = 52/345 (15%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVS-----ELALY----DIRAAEGIGKDLSHINTN 51 ++ VA+ GA+G + L L L L A EG+ +L Sbjct: 42 IINVAVSGAAGMISNHLLFKLASGEVFGPDQPISLKLLGSERSFAALEGVAMELEDSLYP 101 Query: 52 SSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PN 110 +A+ L+ PR PG+ R DL +N I A+ A PN Sbjct: 102 LLRQVSIGIDPYEIFQDAEWALLIGAKPRGPGMERADLLDINGQIFAEQGKALNAVASPN 161 Query: 111 ARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQ 170 +++V+ NP N+ I LK P N +T LD RA+ L K G Sbjct: 162 VKVMVVGNPCNTNALI---CLKNAPNIPPKNFHALTRLDENRAKCQLA-------LKAGV 211 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKS--------LVFQLDKQYEHFIHRVQFGGDE 222 DK + VT+ G HS T +P + ++ + F + VQ G Sbjct: 212 FYDKVS---NVTIWGNHS-TTQVPDFLNAKIHGIPVTEVIRDRKWLEDEFTNMVQTRGGV 267 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 ++K + +A+ +++ A +RS PE + S VY G G Sbjct: 268 LIKKWGRSSAASTAVSIVDA------IRSLVTPTPEGDWFSTGVYTNGNPYG-------- 313 Query: 283 DNSIEYFSLPIVLRNGS------VVSIDTSVLEKLSPREEQLVNT 321 FS+P + V D + +K+ E++L+ Sbjct: 314 IAEDIVFSMPCRSKGDGDYEFVKDVIFDDYLSKKIKKSEDELLAE 358 >4BGU-A nrPDB Length = 303 Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats. Identities = 77/339 (22%), Positives = 129/339 (38%), Gaps = 48/339 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE----GIGKDLSHINTNSSCVGY 57 KV+++GA+G VG L L EL DI E G D +H S Sbjct: 1 TKVSVIGAAGTVGAAAGYNLALRDVCDELVFVDIPKMEDKTVGQAADTNHGIAYDSNTVV 60 Query: 58 DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117 + E+T + + VV+I AG+PR+PG TR DL NA I+ + +++ ++ + + S Sbjct: 61 TQGGYEDT-AGSDVVVITAGIPRQPGQTRIDLAGDNAPIMDDIGSSLAEYNDDFVSITTS 119 Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMG-VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 NPV+ L L + G V+G LD R L D Sbjct: 120 NPVDLLN----RHLYETGDRDRHKVIGFGGRLDSARFRYVLSQRF-----------DVPV 164 Query: 177 MHRKVTVIGGHSGETIIPIITDKSL----VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232 + T++G H G+ +P+ + + + E + +Q ++++ K G+ Sbjct: 165 KNVDATILGEH-GDAQVPVFSKVRVDGNDPAFSADEKEEILGDLQESAMDVIERK---GA 220 Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292 A A E VL E L + L G + F +P Sbjct: 221 TQWGPATGVAHMVEAVLHDT------GEVLPGSLVLDGEFGYEDTA----------FGVP 264 Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331 + L + + + L E L++ A ++LR + Sbjct: 265 VKLGSNGIEEVVEW---DLDDYEADLMDDAAEKLRDQYD 300 >4JCO-A nrPDB Length = 304 Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats. Identities = 72/323 (22%), Positives = 122/323 (37%), Gaps = 48/323 (14%) Query: 19 LLLKLSPYVSELALYDIRAAE----GIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLI 74 + L E+ DI E G D +H S + E+T + + VV+I Sbjct: 19 YNIALRDIADEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRVRQGGYEDT-AGSDVVVI 77 Query: 75 PAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKM 134 AG+PR+PG TR DL NA I++ + +++ + + L SNPV+ L L + Sbjct: 78 TAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVDLLN----RHLYEA 133 Query: 135 GKFKPGNVMG-VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETII 193 G V+G LD R L + D + + T++G H G+ + Sbjct: 134 GDRSREQVIGFGGRLDSARFRYVLSEEF-----------DAPVQNVEGTILGEH-GDAQV 181 Query: 194 PIITDKSLVFQLDK----QYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVL 249 P+ + + + + E + +Q ++++ K G+ A A E +L Sbjct: 182 PVFSKVRVDGTDPEFSGDEKEQLLGDLQESAMDVIERK---GATEWGPARGVAHMVEAIL 238 Query: 250 RSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLE 309 E L A V L G + F +P+ L + V I Sbjct: 239 HDT------GEVLPASVKLEGEFGHEDTA----------FGVPVRLGSNGVEEIVEW--- 279 Query: 310 KLSPREEQLVNTAVKELRKNIEK 332 L E+ L+ A ++L +K Sbjct: 280 DLDDYEQDLMADAAEKLSDQYDK 302 >4UUM-A nrPDB Length = 341 Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats. Identities = 67/342 (19%), Positives = 123/342 (35%), Gaps = 48/342 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSE----LALYDIRAAE----GIGKDLSHINTNSSC 54 V I GA+G +G LS + + L L DI A + +L Sbjct: 6 HVLITGAAGQIGYILSHWIASGELYGDRQVYLHLLDIPPAMNRLTALTMELEDCAFPHLA 65 Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARI 113 + + + A +P KPG R DL N+ I K+ + K+A P+ ++ Sbjct: 66 GFVATTDPKAAFKDIDCAFLVASMPLKPGQVRADLISSNSVIFKNTGEYLSKWAKPSVKV 125 Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQD 173 LVI NP N+ IA+ K + KP N ++ LD RA + L + + Sbjct: 126 LVIGNPDNTNCEIAMLHAKNL---KPENFSSLSMLDQNRAYYEVASKLGVDVKDV----- 177 Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQ-----------YEHFIHRVQFGGDE 222 + V G H GE+++ +T + + Q ++ F ++ + Sbjct: 178 -----HDIIVWGNH-GESMVADLTQATFTKEGKTQKVVDVLDHDYVFDTFFKKIGHRAWD 231 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 I++ + +A + K A + ++++ E LS + +P G Sbjct: 232 ILEHRGFTSAA------SPTKAAIQHMKAWLFGTAPGEVLSMGIPVP-------EGNPYG 278 Query: 283 DNSIEYFSLPI-VLRNGSVVSIDTSVLEKLSPREEQLVNTAV 323 FS P V + G + ++ + + + Sbjct: 279 IKPGVVFSFPCNVDKEGKIHVVEGFKVNDWLREKLDFTEKDL 320 >3D5T-A nrPDB Length = 331 Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats. Identities = 70/351 (19%), Positives = 122/351 (34%), Gaps = 48/351 (13%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDIRAAE----GIGKDLSHINTNSS 53 +VA+ GA+G + L + + + L L D+ A+ G+ +L Sbjct: 11 RVAVTGAAGQIAYSLLFRIANGDLLGKDQPVILQLLDLPQAQAAVKGVVMELDDCAFPLL 70 Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NAR 112 D + +A V L+ PR G+ R DL NA I A+ + A + + Sbjct: 71 AGVVITDDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGAALNEVASRDVK 130 Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172 +LV+ NP N+ IA+ K N + LD RA + L I Sbjct: 131 VLVVGNPANTNAYIAM---KSAPDLPKKNFTAMLRLDHNRALSQLAAKSGKPVASI---- 183 Query: 173 DKTTMHRKVTVIGGHSGETIIPII--------TDKSLVFQLDKQYEHFIHRVQFGGDEIV 224 K+ V G HS T+ P + L+ + FI V G I+ Sbjct: 184 ------EKLAVWGNHS-PTMYPDFRFATAEGESLLKLINDDVWNRDTFIPTVGKRGAAII 236 Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284 +A+ LS A + A A + +R + + ++ + G G Sbjct: 237 EARG------LSSAASAANAAIDHVRDWVLGTN-GKWVTMGIPSDGSY---------GIP 280 Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335 + +P++ NG ++ ++ S + + E R + Sbjct: 281 EDIIYGVPVICENGEYKRVEGLEIDAFSREKMDGTLAELLEERDGVAHLLK 331 >4TVO-A nrPDB Length = 330 Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats. Identities = 69/355 (19%), Positives = 117/355 (32%), Gaps = 50/355 (14%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVS-----ELALYDIR----AAEGIGKDLSHINTNS 52 +KVA+ GA+G +G L L + EL L +I A EG+ +L Sbjct: 6 LKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDDCAFPL 65 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKF-APNA 111 + + L+ PR G+ R DL + N I + A+ A + Sbjct: 66 LSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAVAADDV 125 Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171 R+ V NP N+ IA+ +T LD RA + L I Sbjct: 126 RVGVTGNPANTNALIAMT---NAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDI--- 179 Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQY--------EHFIHRVQFGGDEI 223 +K+T+ G HS T P + + + + + FI V G I Sbjct: 180 -------KKMTIWGNHS-ATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAI 231 Query: 224 VKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGD 283 + A+ + A + A + R + P + +S V G + Sbjct: 232 IDARGAS------SAASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLIS--- 282 Query: 284 NSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338 S P+ + G+ + +++ S ++ + EL L Sbjct: 283 ------SFPVTTKGGNWTIVSGLEIDEFS---RGRIDKSTAELADERSAVTELGL 328 >3DL2-A nrPDB Length = 303 Score = 153 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 67/335 (20%), Positives = 135/335 (40%), Gaps = 52/335 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA-EGIGKDLSHINTNSSCVGYDKDS 61 K+ ++G G +G +L + L L D+ +G DL N + + D Sbjct: 16 KITVVGG-GELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKD--- 71 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121 + ++++VV+ + D+ + N + ++LV A+G ++ ++ +LV S PV Sbjct: 72 -LSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVE 129 Query: 122 SLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 + + K+ F V+G+ NLD R + + + L + ++ Sbjct: 130 IMTYVT----WKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTS-----------GKE 174 Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQ--FGGDEIVKAKQGAGSATLSMA 238 V VIG + K L + ++ +VQ E+++ K G + S+ Sbjct: 175 VWVIGEQGED--------KVLTWSGQEEVVSHTSQVQLSNRAMELLRVK---GQRSWSVG 223 Query: 239 FAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLR-N 297 + A + ++ N K + S+SA A+ NS + SLP +L N Sbjct: 224 LSVADMVDSIV----NNKKKVHSVSAL-----------AKGYYDINSEVFLSLPCILGTN 268 Query: 298 GSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEK 332 G I T++ E + Q +++ L++ ++ Sbjct: 269 GVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL 303 >1B8U-A nrPDB Length = 329 Score = 152 bits (383), Expect = 2e-37, Method: Composition-based stats. Identities = 64/349 (18%), Positives = 117/349 (33%), Gaps = 48/349 (13%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDI------RAAEGIGKDLSHINT 50 ++VA+ GA+G + L + + + L L +I +A +G+ ++ Sbjct: 6 MRVAVTGAAGQICYSLLFRIANGDMLGKDQPVILQLLEIPNEKAQKALQGVMMEIDDCAF 65 Query: 51 NSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP- 109 +A V L+ PR PG+ R DL + NA I A+ A Sbjct: 66 PLLAGMTAHADPMTAFKDADVALLVGARPRGPGMERKDLLEANAQIFTVQGKAIDAVASR 125 Query: 110 NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIG 169 N ++LV+ NP N+ IA+ K N + LD RA + + I Sbjct: 126 NIKVLVVGNPANTNAYIAM---KSAPSLPAKNFTAMLRLDHNRALSQIAAKTGKPVSSI- 181 Query: 170 QEQDKTTMHRKVTVIGGHSGET-------IIPIITDKSLVFQLDKQYEHFIHRVQFGGDE 222 K+ V G HS I + K ++ + F+ V G Sbjct: 182 ---------EKLFVWGNHSPTMYADYRYAQIDGASVKDMINDDAWNRDTFLPTVGKRGAA 232 Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282 I+ A+ +S A + A A + + + + + + G + Sbjct: 233 IIDARG------VSSAASAANAAIDHIHDWVLGTA-GKWTTMGIPSDGSYGIPEG----- 280 Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331 F P+ NG + ++ S + + E + ++ Sbjct: 281 ----VIFGFPVTTENGEYKIVQGLSIDAFSQERINVTLNELLEEQNGVQ 325 >6IHE-A nrPDB Length = 303 Score = 146 bits (369), Expect = 1e-35, Method: Composition-based stats. Identities = 62/340 (18%), Positives = 127/340 (37%), Gaps = 47/340 (13%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVG-YDK 59 KV +GA G +GQ ++ +S V E +YDI + +L H Sbjct: 2 KVGFIGA-GKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFATKGIKANVLG 60 Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119 + + +S +V+I AG PRKPG++R DLF NA I+ L + P A L+++NP Sbjct: 61 TNSLDDVSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKLPSKNPGAIYLMVANP 120 Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179 V+ + + ++ K+ + ++ +R +F+ L + + Sbjct: 121 VDMMASVFMKYSKQFT------ISAGDQVETMRMRSFIAKKLKIPVTSVDGF-------- 166 Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQY----EHFIHRVQFGGDEIVKAKQGAGSATL 235 +GG GE + + + + + ++ + V+ EI++ G T Sbjct: 167 ----VGGEHGEDAVVLWSTVKIKGKPVDEFNINKDEVSDYVKKIPGEIIRV---IGGTTW 219 Query: 236 SMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL 295 A + + S + + I + S P V+ Sbjct: 220 GPGTIIADIIKSIAFSENRVMSIATP------------------KEYEKEIIHVSAPTVV 261 Query: 296 RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335 + S+++ + EK + + ++N+++ + Sbjct: 262 GSSIGPSLESLLDEKDRWHLNSAMKDFYEAYKENLKQLEQ 301 >1HYH-A nrPDB Length = 309 Score = 126 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 58/345 (16%), Positives = 117/345 (33%), Gaps = 52/345 (15%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVGYDKD 60 K+ I+G G VG ++ L + D A+ D N G Sbjct: 3 KIGIIGL-GNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQIDFQDAMANLEAHGNIVI 61 Query: 61 SIENTLSNAQVVLIPAGVPR----KPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + L++A VV+ G + P R K + +V+S+ T + + + ++VI Sbjct: 62 NDWAALADADVVISTLGNIKLQQDNPTGDRFAELKFTSSMVQSVGTNLKESGFHGVLVVI 121 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMG-VTNLDLVRAETFLVDYL-----MLKNPKIGQ 170 SNPV+ + + + + F V+G T LD R + + + + +G+ Sbjct: 122 SNPVDVITAL----FQHVTGFPAHKVIGTGTLLDTARMQRAVGEAFDLDPRSVSGYNLGE 177 Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGA 230 + + + G T L D + GG ++ K Sbjct: 178 HGNSQFVAWSTVRVMGQPIVT---------LADAGDIDLAAIEEEARKGGFTVLNGK--- 225 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290 G + +A + + A+ V+ H E D+ Y S Sbjct: 226 GYTSYGVATSAIRIAKAVMADAHAEL--------------------VVSNRRDDMGMYLS 265 Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335 P ++ V++ T L+ E++ + + +++ ++ Sbjct: 266 YPAIIGRDGVLAETTL---DLTTDEQEKLLQSRDYIQQRFDEIVD 307 >3FEF-A nrPDB Length = 450 Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 25/158 (15%), Positives = 57/158 (36%), Gaps = 25/158 (15%) Query: 2 VKVAILGAS--GGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59 +K+A +G G +S L +ALYD+ ++ ++ + Y+ Sbjct: 6 IKIAYIGGGSQGWARSLMSDLSIDERMSGTVALYDLDFEAAQKNEVIGNHSGNGRWRYEA 65 Query: 60 -DSIENTLSNAQVVLIP------------AGVPRKPG--LTRDDLFK--------MNAGI 96 +++ LS A +V+I +P + G + D I Sbjct: 66 VSTLKKALSAADIVIISILPGSLDDMEVDVHLPERCGIYQSVGDTVGPGGIIRGLRAVPI 125 Query: 97 VKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKM 134 + A+ +AP + ++ +NP++ + + + Sbjct: 126 FAEIARAIRDYAPESWVINYTNPMSVCTRVLYKVFPGI 163 >3PLN-A nrPDB Length = 424 Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 45/126 (35%), Gaps = 19/126 (15%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG----------IGKDLSHINTN 51 +K+ I G +G VG +L+ + E+ DI A+ + K++ Sbjct: 37 MKITISG-TGYVGLSNGVLIAQN---HEVVALDIVQAKVDMLNQKISPIVDKEIQEYLAE 92 Query: 52 SSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA 111 + NA V+I P N V++++ V + PNA Sbjct: 93 KPLNFRATTDKHDAYRNADYVIIATPTDYDPKTN-----YFNTSTVEAVIRDVTEINPNA 147 Query: 112 RILVIS 117 +++ S Sbjct: 148 VMIIKS 153 >4XRR-A nrPDB Length = 456 Score = 35.5 bits (80), Expect = 0.032, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 37/110 (33%), Gaps = 20/110 (18%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK-- 59 +KV I GA G VG L++ L +E+ D + G DL G Sbjct: 16 LKVVIAGA-GYVGTCLAVTLAGRG--AEVVAVD--SDPGTVADLRAGRCRLPEPGLAGAV 70 Query: 60 -----------DSIENTLSNAQVVLIPAGVPRKPG--LTRDDLFKMNAGI 96 + + + A VV++ G P G + D L I Sbjct: 71 RDLAATGRLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQLVAACEQI 120 >1HE4-A nrPDB Length = 206 Score = 35.1 bits (79), Expect = 0.039, Method: Composition-based stats. Identities = 32/183 (17%), Positives = 59/183 (32%), Gaps = 24/183 (13%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K+AI GA+G G + Y + + D G +H+ D + Sbjct: 5 KIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAAD---V 61 Query: 63 ENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNA--GIVKSLVTAVGKFAPNARILVISNPV 120 + T++ V++ G TR+DL +++V A+ + + S Sbjct: 62 DKTVAGQDAVIVLLG-------TRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTS--- 111 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 L K P + VT+ D +R L + + + + Sbjct: 112 -------AFLLWDPTKVPP-RLQAVTD-DHIRMHKVLRESGLKYVAVMPPHIGDQPLTGA 162 Query: 181 VTV 183 TV Sbjct: 163 YTV 165 >3WMX-A nrPDB Length = 358 Score = 34.4 bits (77), Expect = 0.081, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG 56 K+ I+GA+G +G L+L L + + D+ G L+H N++ G Sbjct: 27 KILIVGANGQIGSELALALAERYGRTNVITSDVVPT-GRHVHLTHEMLNATDRG 79 >5K0S-A nrPDB Length = 536 Score = 34.0 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 23/75 (30%), Gaps = 9/75 (12%) Query: 47 HINTNSSCVGYDKDSIENTLSNAQVVLIPA----GV-----PRKPGLTRDDLFKMNAGIV 97 HI + D + L+ V + G+ RK G+T DL N Sbjct: 41 HIGHAYELIATDAMARFQRLNGMDVYFLTGTDEHGIKMLQSARKEGITPRDLADRNTSAF 100 Query: 98 KSLVTAVGKFAPNAR 112 + + + + Sbjct: 101 RRMAEVLNSSNDDYI 115 >3GRP-A nrPDB Length = 266 Score = 34.0 bits (76), Expect = 0.092, Method: Composition-based stats. Identities = 29/157 (18%), Positives = 51/157 (32%), Gaps = 23/157 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K + GA+GG+G+ ++ + L + I DL S D+ SI Sbjct: 29 KALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDRKSI 88 Query: 63 -------ENTLSNAQVVLIPAGVPRKPGLTR------DDLFKMNAGIVKSLVTAVGKF-- 107 E + +++ AG+ R R DD+ +N +L + Sbjct: 89 KQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSMM 148 Query: 108 --------APNARILVISNPVNSLVPIAVETLKKMGK 136 + + V+ NP + A L K Sbjct: 149 RRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSK 185 >3WYE-A nrPDB Length = 256 Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 41/94 (43%), Gaps = 12/94 (12%) Query: 1 MVKVAILGASGG-VGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59 M KVA++ +G +G+ ++L L + +A Y+ A+ + +++ ++ V D Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 60 DSIENTLS----------NAQVVLIPAGVPR-KP 82 + + V++ AG+ + KP Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKP 94 >1ORR-A nrPDB Length = 347 Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 47/128 (36%), Gaps = 21/128 (16%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLS-----------HIN 49 M K+ I G G +G L+ +L ++D + +G +L H + Sbjct: 1 MAKLLITGGCGFLGSNLASFALSQGI--DLIVFDNLSRKGATDNLHWLSSLGNFEFVHGD 58 Query: 50 TNSSCVGY---DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGK 106 + K ++ A V + + P + F++N G +L+ AV + Sbjct: 59 IRNKNDVTRLITKYMPDSCFHLAGQVAMTTSID-NPCMD----FEINVGGTLNLLEAVRQ 113 Query: 107 FAPNARIL 114 + N I+ Sbjct: 114 YNSNCNII 121 >4F3Y-A nrPDB Length = 272 Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 1/72 (1%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +K+AI GASG +G+ L + +P + + D + +G+D + D Sbjct: 8 MKIAIAGASGRMGRMLIEAVLAAPDATLVGALDRTGSPQLGQD-AGAFLGKQTGVALTDD 66 Query: 62 IENTLSNAQVVL 73 IE + A ++ Sbjct: 67 IERVCAEADYLI 78 >5C3M-A nrPDB Length = 447 Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 26/196 (13%), Positives = 57/196 (29%), Gaps = 37/196 (18%) Query: 27 VSELALYDIRAAEGIGKDLSHIN------TNSSCVGYDKDSIENTLSNAQVV---LIPAG 77 V EL L DI + + + + + L A V G Sbjct: 33 VGELWLVDIPEGKEKLEIVGALAKRMVEKAGVPIEIHLTLDRRRALEGADFVTTQFRVGG 92 Query: 78 VPRKPGLTRDDL------FKMN-----------AGIVKSLVTAVGKFAPNARILVISNPV 120 + + R L + N ++ ++ + + P+A ++ +NP Sbjct: 93 LEARAKDERIPLKYGVIGQETNGPGGLFKGLRTIPVILDIIRDMEELCPDAWLINFTNPA 152 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180 + + K+ V+G+ N+ + + L + ++ D Sbjct: 153 GMVTEAVLRYTKQ------EKVVGLCNVPIGM-RMGVAKLLGVDADRV--HID--FAGLN 201 Query: 181 VTVIGGHSGETIIPII 196 V G H + + Sbjct: 202 HMVFGLHVYLDGVEVT 217 >4NBV-A nrPDB Length = 246 Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 23/98 (23%), Positives = 37/98 (37%), Gaps = 9/98 (9%) Query: 3 KVAIL-GASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +VAI+ GA+ G+G + + + L D++ A T ++ Y D Sbjct: 6 RVAIITGAAAGIGFATAQRFAEDGAI--VVLCDVQEARVREAAARLAATGATVSAYRVDV 63 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKS 99 +A V + A R D+ NAGI K Sbjct: 64 TRRDEVDAMVAAVLAA------HQRVDILVNNAGITKD 95 >2EW8-A nrPDB Length = 249 Score = 32.4 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 18/96 (18%), Positives = 40/96 (41%), Gaps = 11/96 (11%) Query: 3 KVAIL-GASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 K+A++ G + G+G+ ++ + +++A+ D+ A + ++ V D Sbjct: 8 KLAVITGGANGIGRAIAERFAVEG--ADIAIADLVPAPEAEAAIRNLGRRVLTVKCDVSQ 65 Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIV 97 + + + V+ G R D+ NAGI Sbjct: 66 PGDVEAFGKQVISTFG--------RCDILVNNAGIY 93 >5ZF1-A nrPDB Length = 301 Score = 31.7 bits (70), Expect = 0.51, Method: Composition-based stats. Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 28/96 (29%) Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKD----LSHINTNSSCVGYDKD 60 ++G S VG P++++L D R G+G D + H T KD Sbjct: 162 VVIGRSKNVGMPIAMMLHS----------DKRHESGLGMDATVTICHRYTP-------KD 204 Query: 61 SIENTLSNAQVVLIPAGVPR-------KPGLTRDDL 89 +E NA +++ G+P+ KPG T D+ Sbjct: 205 KLEAYCRNADIIITATGLPKLIKADMVKPGATIIDV 240 >1GEG-A nrPDB Length = 256 Score = 31.3 bits (69), Expect = 0.63, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 38/90 (42%), Gaps = 11/90 (12%) Query: 1 MVKVAILGASGG-VGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59 M KVA++ +G +G+ ++L L + +A Y+ A+ + +++ ++ V D Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60 Query: 60 DSIENTLS----------NAQVVLIPAGVP 79 + + V++ AGV Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVA 90 >2BE7-D nrPDB Length = 153 Score = 31.3 bits (69), Expect = 0.66, Method: Composition-based stats. Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 5/75 (6%) Query: 45 LSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKM-NAGIVKSLVTA 103 + HI + S+ +T V +P K G DL K+ N I KS Sbjct: 17 IDHIPSGQGVKILKLFSLTDTKQRVTVGF---NLPTKDG-NAKDLIKVENTEITKSQANQ 72 Query: 104 VGKFAPNARILVISN 118 + APNA I +I N Sbjct: 73 LALLAPNATINIIEN 87 >1BXK-A nrPDB Length = 355 Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 17/46 (36%), Gaps = 1/46 (2%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLS 46 M K+ I G +G +G L + + + D G L+ Sbjct: 1 MRKILITGGAGFIGSALVRYIIN-ETSDAVVVVDKLTYAGNLMSLA 45 >5UYY-A nrPDB Length = 381 Score = 30.9 bits (68), Expect = 0.76, Method: Composition-based stats. Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 13/68 (19%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI-----------GKDLSHINTN 51 KV ++G +G +G L+L +K + + YDI + DL H Sbjct: 19 KVVLIG-TGLIGGSLALAIK-KDHDVTITGYDIFQEQVERAKELHVVDEIAVDLQHACEE 76 Query: 52 SSCVGYDK 59 + + + Sbjct: 77 AHLIVFAS 84 >1KEU-A nrPDB Length = 361 Score = 30.9 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNS 52 +K+ I G +G +G + + + D G + LS I+ ++ Sbjct: 1 MKILITGGAGFIGSAVV-RHIIKNTQDTVVNIDKLTYAGNLESLSDISESN 50 >5EES-A nrPDB Length = 247 Score = 30.9 bits (68), Expect = 0.85, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 6/72 (8%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +KV +LGA G VGQ + + +L L A G+ DLS + N + V D + Sbjct: 2 IKVGVLGAKGRVGQTI---VAAVNESDDLELV---AEIGVDDDLSLLVDNGAEVVVDFTT 55 Query: 62 IENTLSNAQVVL 73 + N + + Sbjct: 56 PNAVMGNLEFCI 67 >2GFQ-A nrPDB Length = 298 Score = 30.9 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 23/178 (12%), Positives = 51/178 (28%), Gaps = 44/178 (24%) Query: 177 MHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLS 236 + V H G T + + + + ++++ + EI+ Sbjct: 152 LGWTVCYEATHHGPTELEVPSFFIEIGSSEEEW------INDRAGEII------------ 193 Query: 237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY------FS 290 AE ++ N + + + G K + + + + ++ Sbjct: 194 --------AETIIYVLDNYEKGRSKFKVALGIGGGHYAPKQTKRALEGDLAFGHILPKYA 245 Query: 291 LPI-------VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSS 341 P+ L V K S E + + ++ + E G FI D S Sbjct: 246 QPVSRDVMIKALNRFGEKVEAIYVDWKGSRGETRQLAKSLAQ-----ELGLEFIKDGS 298 >2CVO-A nrPDB Length = 366 Score = 30.5 bits (67), Expect = 0.96, Method: Composition-based stats. Identities = 20/75 (26%), Positives = 27/75 (36%), Gaps = 3/75 (4%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL-YDIRAAEGIGKDLSHINTNSSCVGYDKD 60 V++A+LGASG G + LL P + D +A E G H+ T Sbjct: 24 VRIAVLGASGYTGAEIVRLLANHPQFRIKVMTADRKAGEQFGSVFPHLITQDLPNLVAVK 83 Query: 61 SIENTLSNAQVVLIP 75 SN V Sbjct: 84 D--ADFSNVDAVFCC 96 >4WOK-A nrPDB Length = 336 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 2/31 (6%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYD 34 V ++G +G +G + LL Y +YD Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAP--VVYD 42 >3WTC-A nrPDB Length = 262 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 15/91 (16%) Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIR-----AAEGIGKDLSHINTNSSCVGYDK 59 A+ GA+ G+G+ ++L L +++ L D++ + L + ++ Sbjct: 12 AVTGAAQGIGKAIALRLAKDG--ADVILLDVKQDTLAETAKEVEALGRRAVALTADISNR 69 Query: 60 DSIENTLSNA-------QVVLIPAGVPR-KP 82 D +TL++A +++ AG+ + KP Sbjct: 70 DQFRSTLADAAKTLGGLDIMVNNAGICQVKP 100 >2YV3-A nrPDB Length = 331 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 32/161 (19%), Positives = 60/161 (37%), Gaps = 27/161 (16%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60 ++VA++GA+G VG+ + +L+ + +SEL LY + G+ + Sbjct: 1 MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPV-------E 53 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDD---------LFKMNAGIVKSL--VTAVGKFAP 109 + +VL AG G++R L N+ + V V Sbjct: 54 PLPEGPLPVDLVLASAGG----GISRAKALVWAEGGALVVDNSSAWRYEPWVPLVVPEVN 109 Query: 110 NARIL----VISNPVNSLVPIAVETLKKMGKFKPGNVMGVT 146 +I +I+NP + +A+ F+ V+ T Sbjct: 110 REKIFQHRGIIANPNCTTAILAMALWPLHRAFQAKRVIVAT 150 >2NNL-D nrPDB Length = 337 Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 15/78 (19%), Positives = 26/78 (33%), Gaps = 5/78 (6%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-----D 58 V + GASG +G L + L Y + D + + L + + D Sbjct: 8 VCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKADLAD 67 Query: 59 KDSIENTLSNAQVVLIPA 76 + S + + V A Sbjct: 68 EGSFDEAIKGCTGVFHVA 85 >4A7P-A nrPDB Length = 446 Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 53/150 (35%), Gaps = 23/150 (15%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYD-------------IRAAEGIGKDLSHI 48 V++A++G +G VG S + E+ D + E L Sbjct: 9 VRIAMIG-TGYVGLVSGACF--SDFGHEVVCVDKDARKIELLHQNVMPIYEPGLDALVAS 65 Query: 49 NTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA 108 N + + + D E + +A V I G P + G DL + A + + + K Sbjct: 66 NVKAGRLSFTTDLAEG-VKDADAVFIAVGTPSRRGDGHADLSYVFAA-AREIAENLTK-- 121 Query: 109 PNARILVISNPV---NSLVPIAVETLKKMG 135 P+ + + PV + + I E G Sbjct: 122 PSVIVTKSTVPVGTGDEVERIIAEVAPNSG 151 >3RFT-A nrPDB Length = 267 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 21/119 (17%), Positives = 44/119 (36%), Gaps = 10/119 (8%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60 M ++ + GA+G +G+ + L P L L D+ + G + C D + Sbjct: 3 MKRLLVTGAAGQLGRVMRERLA--PMAEILRLADLSPLDPAGPN----EECVQCDLADAN 56 Query: 61 SIENTLSNAQVVLIPAGVP-RKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118 ++ ++ ++ G+ KP + + N + +L A + SN Sbjct: 57 AVNAMVAGCDGIVHLGGISVEKPFE---QILQGNIIGLYNLYEAARAHGQPRIVFASSN 112 >2Q1W-A nrPDB Length = 333 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 18/85 (21%), Positives = 27/85 (31%), Gaps = 5/85 (5%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60 M KV I G G +G ++ LL ++ D A H N Sbjct: 21 MKKVFITGICGQIGSHIAELLLERG--DKVVGIDNFATGRREHLKDHPNLTFVEGSIADH 78 Query: 61 SIENTLSN---AQVVLIPAGVPRKP 82 ++ N L V+ A + P Sbjct: 79 ALVNQLIGDLQPDAVVHTAASYKDP 103 >1LSS-A nrPDB Length = 140 Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 35/99 (35%), Gaps = 7/99 (7%) Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHINTNSSCVGYDKDSIE 63 I+ G VG L+ L + ++ L DI + ++ + N C Sbjct: 8 IIAGIGRVGYTLAKSLSEKGH--DIVLIDIDKDICKKASAEIDALVINGDCTKIKTLEDA 65 Query: 64 NTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT 102 + +A + + G ++ L + GI K++ Sbjct: 66 G-IEDADMYIAVTGKEEVNLMS--SLLAKSYGINKTIAR 101 >3G05-A nrPDB Length = 576 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 20/141 (14%), Positives = 46/141 (32%), Gaps = 12/141 (8%) Query: 87 DDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK--KMGKFKPGNVMG 144 +DL N +V ++ KF A +L + ++ + I ++ + G + Sbjct: 152 EDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPL-- 209 Query: 145 VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQ 204 R L + K G +V+ G+ +P+ + Q Sbjct: 210 -----SRRLREL---PLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQ 261 Query: 205 LDKQYEHFIHRVQFGGDEIVK 225 +Q +I ++++ Sbjct: 262 HPQQVPCYITHTNEKTHDVIR 282 >3CP2-A nrPDB Length = 649 Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 20/141 (14%), Positives = 46/141 (32%), Gaps = 12/141 (8%) Query: 87 DDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK--KMGKFKPGNVMG 144 +DL N +V ++ KF A +L + ++ + I ++ + G + Sbjct: 146 EDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPL-- 203 Query: 145 VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQ 204 R L + K G +V+ G+ +P+ + Q Sbjct: 204 -----SRRLREL---PLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQ 255 Query: 205 LDKQYEHFIHRVQFGGDEIVK 225 +Q +I ++++ Sbjct: 256 HPQQVPCYITHTNEKTHDVIR 276 >5JW6-A nrPDB Length = 371 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 44/302 (14%), Positives = 95/302 (31%), Gaps = 21/302 (6%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI---RAAEGIGKDLSHINTNSSCVGYDK 59 K +LGA+G VGQ LLL P++ EL A + + T + Sbjct: 8 KCGVLGATGSVGQRFILLLADHPFL-ELHAIGASNRSAGKKYKDAVRWKQTTAMSERLSN 66 Query: 60 DSIENTLSN--AQVVLIPAGVPR-KPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + + ++ + L+ +G+ G + K + + + + + ++ Sbjct: 67 LVLRDCRADQFSDCDLVFSGLNSDVAGEIEMEFIKAEIPVF----SNAKNYRKHPLVPLV 122 Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 VN + +K K G ++ + A +V K G ++ Sbjct: 123 VPTVNPQHLDLIPHQRKEFGLKKGFLVC----NSNCAVIGVVIPFAALQAKFGPVEEVEV 178 Query: 177 MHRKVTVIGGHSGETIIPIITDK-SLVFQLDKQYEHFIHRVQFG----GDEIVKAKQGA- 230 + G+ G + I+ + + + + E+ ++ + K Sbjct: 179 FTEQAVSGAGYPGVPSMDIMDNVIPYISGEEDKLENEAQKILGSLNADATAFDEQKGLTV 238 Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290 G+ + A LR + P E + + + K +I+ F Sbjct: 239 GATCTRVGVTDGHMAFVSLRFKNRPGPSAEEVKQAMREYQSEAQKLGCPSAPREAIKVFD 298 Query: 291 LP 292 P Sbjct: 299 EP 300 >5ITV-A nrPDB Length = 255 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 27/93 (29%), Gaps = 10/93 (10%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIE 63 V I G + G+G + + + DI A+G N V D Sbjct: 10 VLITGGASGIGYAAVQAFLGQQ--ANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEA 67 Query: 64 NTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGI 96 + + G D+ NAGI Sbjct: 68 ACQHAVESAVHTFGG--------LDVLINNAGI 92 >4B4O-A nrPDB Length = 298 Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 2/39 (5%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG 40 ++V + G +G +G L+ LL + E+ L + G Sbjct: 1 MRVLVGGGTGFIGTALTQLLNARGH--EVTLVSRKPGPG 37 >1E3W-A nrPDB Length = 261 Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 14/84 (16%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHIN--TNSSCVGYDKDSI 62 I G + G+G + L + L D+ +EG + + + + Sbjct: 14 VITGGASGLGLSTAKRLVGQGATA--VLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71 Query: 63 ENTLSNA-------QVVLIPAGVP 79 + L+ A V + AG+ Sbjct: 72 QAALTLAKEKFGRIDVAVNCAGIA 95 >5TEK-A nrPDB Length = 250 Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 3/31 (9%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL 32 ++V +LGA G VG + + +L L Sbjct: 6 MRVGVLGAKGKVGATMVRAVA---AADDLTL 33 >2FV8-A nrPDB Length = 207 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 22/127 (17%), Positives = 45/127 (35%), Gaps = 19/127 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K+ ++G G G+ L++ E+ + + E D+ +D Sbjct: 27 KLVVVG-DGACGKTCLLIVFSKDEFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 83 Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115 E+ + + V+L+ V D + I + V V F PN I++ Sbjct: 84 EDYDRLRPLSYPDTDVILMCFSV------DSPDSLE---NIPEKWVPEVKHFCPNVPIIL 134 Query: 116 ISNPVNS 122 ++N + Sbjct: 135 VANKKDL 141 >3PWZ-A nrPDB Length = 272 Score = 29.4 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 4/82 (4%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALY--DIRAAEGIGKDLSHINTNSSCVGYDKD 60 +V +LGA G V +LL L SEL + D+ A + +L H S + Sbjct: 122 RVLLLGAGGAVRG--ALLPFLQAGPSELVIANRDMAKALALRNELDHSRLRISRYEALEG 179 Query: 61 SIENTLSNAQVVLIPAGVPRKP 82 + + NA + A +P P Sbjct: 180 QSFDIVVNATSASLTADLPPLP 201 >3RSH-A nrPDB Length = 251 Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 18/100 (18%) Query: 3 KVA-ILGASGGVGQPLSLLLKLSP---------YVSELALYDIRAAEGIGKDLSHINTNS 52 KVA + GAS G+G+ ++ LL A+ D G G L+ N S Sbjct: 13 KVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPES 72 Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKM 92 +I + +++ AG+ TRD+L Sbjct: 73 IEAVL--KAITDEFGGVDILVNNAGI------TRDNLLMR 104 >2C54-A nrPDB Length = 379 Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 13/69 (18%), Positives = 25/69 (36%), Gaps = 21/69 (30%) Query: 2 VKVAILGASGGVGQPLSLLLKLSP------------------YVSELALYDIRAAEG--- 40 +K++I GA G + ++ LK + E L D+R E Sbjct: 30 LKISITGAGGFIASHIARRLKHEGHYVIASDWKKNEHMTEDMFCDEFHLVDLRVMENCLK 89 Query: 41 IGKDLSHIN 49 + + + H+ Sbjct: 90 VTEGVDHVF 98 >6BI4-A nrPDB Length = 346 Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 11/79 (13%), Positives = 27/79 (34%), Gaps = 5/79 (6%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG---IGKDLSHINTNSSCVGY- 57 + + + G +G +G + S ++ +D G K + G Sbjct: 25 MNILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGEI 84 Query: 58 -DKDSIENTLSNAQVVLIP 75 + + +E+ + V +I Sbjct: 85 QNGELLEHVIKERDVQVIV 103 >1YS4-A nrPDB Length = 354 Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 29/74 (39%), Gaps = 9/74 (12%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 +KV +LGA+G VGQ LL P AL + G +C + Sbjct: 9 IKVGVLGATGSVGQRFVQLLADHPMFELTALAASERSAGK-------KYKDACYWFQDRD 61 Query: 62 IENTLSNAQVVLIP 75 I + +V+IP Sbjct: 62 IPENIK--DMVVIP 73 >5JCP-B nrPDB Length = 419 Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 43/127 (33%), Gaps = 19/127 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K+ I+G G G+ L++ E+ + + E D+ +D Sbjct: 245 KLVIVG-DGACGKTCLLIVNSKDQFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 301 Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115 E+ + + V+L+ + D + I + V F PN I++ Sbjct: 302 EDYDRLRPLSYPDTDVILMCFSI------DSPDSLE---NIPEKWTPEVKHFCPNVPIIL 352 Query: 116 ISNPVNS 122 + N + Sbjct: 353 VGNKKDL 359 >3PZR-A nrPDB Length = 370 Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 14/81 (17%), Positives = 24/81 (29%), Gaps = 13/81 (16%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61 ++V ++G G VG L + D E + S I + G D Sbjct: 1 MRVGLVGWRGMVGSVLMQRMVEER--------DFDLIEPVFFSTSQIGVPAPNFGKDAGM 52 Query: 62 IENTL-----SNAQVVLIPAG 77 + + V+ G Sbjct: 53 LHDAFDIESLKQLDAVITCQG 73 >5G4J-A nrPDB Length = 446 Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 17/132 (12%), Positives = 39/132 (29%), Gaps = 13/132 (9%) Query: 150 LVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI----GGHSGETII--PIITDKSLVF 203 VRA + D + + +++ + GH + P+ + + L+ Sbjct: 170 HVRALR-IPDVSGIAEVDVPVLLEQSLADVDAAIASLQAAGHGVSVFLFDPLFSTEGLLQ 228 Query: 204 QLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKF------AEEVLRSFHNEKP 257 E RV+ G ++ + +G G + + + N P Sbjct: 229 LPSGYIEGVATRVRAAGGLVISDEVQSGFGRTGSGMWGYQMFNVEPELVTMGKPMGNGHP 288 Query: 258 ETESLSAFVYLP 269 ++ L Sbjct: 289 IGAVVTTAELLD 300 >3PRY-A nrPDB Length = 268 Score = 29.0 bits (63), Expect = 3.4, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 28/113 (24%) Query: 164 KNPKIGQEQDKTTMHRKVTVIGGH---SGETIIPIITDKSLVFQLDKQY----------- 209 KN K+G +D T R ++ H SG+ + + S + + K Sbjct: 153 KNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQV 212 Query: 210 --EHFIHRVQFGGDEIV------------KAKQGAGSATLSMAFAGAKFAEEV 248 F+ RV+ G E+V + K+ G + +S+ G + AE + Sbjct: 213 ANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELAENL 265 >3EMK-A nrPDB Length = 246 Score = 29.0 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 14/85 (16%), Positives = 33/85 (38%), Gaps = 7/85 (8%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K + GA+GG+G+ ++ L + L + + +L D++++ Sbjct: 9 KALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDREAV 68 Query: 63 -------ENTLSNAQVVLIPAGVPR 80 E + +++ AG+ R Sbjct: 69 KALGQKAEEEMGGVDILVNNAGITR 93 >2ZJ1-A nrPDB Length = 495 Score = 28.6 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 14/76 (18%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYD-IRAAEGIGKDLSHINTNSSCVGYDKDS 61 KV I G G VG+ + +K + D I A + + + G+D + Sbjct: 277 KVLICG-YGDVGKGCAEAMKGQGARVSVTEIDPINALQAMME------------GFDVVT 323 Query: 62 IENTLSNAQVVLIPAG 77 +E + +A +V+ G Sbjct: 324 VEEAIGDADIVVTATG 339 >5TEN-A nrPDB Length = 269 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 30/73 (41%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60 MV++A+ GA+G +G+ L +P A + + +G DL + D Sbjct: 1 MVRIAVAGAAGRMGRNLVKAAHHNPVAKVAAGSERPESSLVGVDLGELCGEGKFDVVVCD 60 Query: 61 SIENTLSNAQVVL 73 + + V++ Sbjct: 61 DLAKQIDQFDVII 73 >4G65-A nrPDB Length = 461 Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats. Identities = 11/33 (33%), Positives = 18/33 (54%), Gaps = 3/33 (9%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYD 34 +K+ ILGA G VG L+ L +++ + D Sbjct: 4 MKIIILGA-GQVGGTLAENLV--GENNDITIVD 33 >2R00-A nrPDB Length = 336 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%) Query: 4 VAILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGI 41 VAI GA+G VG+ + +L+ + V EL L +EG Sbjct: 6 VAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGK 44 >2EP5-A nrPDB Length = 350 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 21/30 (70%), Gaps = 1/30 (3%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELA 31 +KV++LG++G VGQ + +L PY+ EL Sbjct: 5 IKVSLLGSTGMVGQKMVKMLAKHPYL-ELV 33 >3TZ6-A nrPDB Length = 344 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 7/75 (9%) Query: 4 VAILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 + I+GA+G VGQ + LL + S + + ++G +D+ Sbjct: 4 IGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEV------EDAE 57 Query: 63 ENTLSNAQVVLIPAG 77 S + L AG Sbjct: 58 TADPSGLDIALFSAG 72 >4MOW-A nrPDB Length = 256 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 37/99 (37%), Gaps = 10/99 (10%) Query: 3 KVAIL-GASGGVGQPLSLLLKLSPYVSELALYDIRA-AEGIGKDLSHINTNSSCVGYDKD 60 KVAI+ GAS G+G ++ L + +A A+ + ++ + VG D Sbjct: 15 KVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGGDVS 74 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKS 99 + + G R D+ N+G+ + Sbjct: 75 KAADAQRIVDTAIETYG--------RLDVLVNNSGVYEF 105 >2BKA-A nrPDB Length = 242 Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 7/90 (7%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK-DSI 62 V ILGASG G+ L + S++ L R + ++N V ++K D Sbjct: 21 VFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQE--VVDFEKLDDY 78 Query: 63 ENTLSNAQVVLIPAGVPRK----PGLTRDD 88 + V G R G R D Sbjct: 79 ASAFQGHDVGFCCLGTTRGKAGAEGFVRVD 108 >3W9B-A nrPDB Length = 328 Score = 28.6 bits (62), Expect = 4.4, Method: Composition-based stats. Identities = 9/40 (22%), Positives = 21/40 (52%) Query: 97 VKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGK 136 ++S V + FAP+ + V++ P+++L A ++ Sbjct: 128 IRSKVDRLMAFAPDYKGTVLAGPLDALAVSAPSVWQQTTG 167 >4YWJ-A nrPDB Length = 276 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 13/74 (17%), Positives = 30/74 (40%), Gaps = 1/74 (1%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSEL-ALYDIRAAEGIGKDLSHINTNSSCVGYDK 59 M ++A++GA+G +G+ L ++ + + L A D + +G D + Sbjct: 9 MRRIAVVGAAGRMGKNLIEAVQQTGGAAGLTAAVDRPDSTLVGADAGELAGLGRIGVPLS 68 Query: 60 DSIENTLSNAQVVL 73 + V++ Sbjct: 69 GDLGKVCEEFDVLI 82 >2GAS-A nrPDB Length = 307 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 44/116 (37%), Gaps = 18/116 (15%) Query: 3 KVAILGASGGVGQPLSLL-LKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY---- 57 K+ ILG +G +G+ + +K L I AA K+ N S V Sbjct: 4 KILILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLGVILLEGD 63 Query: 58 --DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSL--VTAVGKFAP 109 D +++ + +V+ AG R L + I+K++ V KF P Sbjct: 64 INDHETLVKAIKQVDIVICAAG--------RL-LIEDQVKIIKAIKEAGNVKKFFP 110 >6BMQ-A nrPDB Length = 523 Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 37/109 (33%), Gaps = 2/109 (1%) Query: 118 NPV-NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176 NP+ + I L + ++P G D L + L I E + Sbjct: 45 NPLEDLKTIIKKSPLPTLFTYRPKWEGGQYEGDENERRDVLRLAMELGADYIDVELQVAS 104 Query: 177 MHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVK 225 K + G G+ + + + + + + R+Q G +IVK Sbjct: 105 EFIKS-IDGKKPGKFKVIVSSHNYQNTPSVEDLDGLVARIQQTGADIVK 152 >5C2K-A nrPDB Length = 415 Score = 28.2 bits (61), Expect = 4.8, Method: Composition-based stats. Identities = 19/127 (14%), Positives = 41/127 (32%), Gaps = 18/127 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K ++ G G+ L++ E+ + + E D+ +D Sbjct: 13 KKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 70 Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115 E+ + + V+L+ + D + I + V F PN I++ Sbjct: 71 EDYDRLRPLSYPDTDVILMCFSI------DSPDSLE---NIPEKWTPEVKHFCPNVPIIL 121 Query: 116 ISNPVNS 122 + N + Sbjct: 122 VGNKKDL 128 >5ZHX-e nrPDB Length = 198 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 19/127 (14%), Positives = 41/127 (32%), Gaps = 18/127 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 K ++ G G+ L++ E+ + + E D+ +D Sbjct: 11 KKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 68 Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115 E+ + + V+L+ + D + I + V F PN I++ Sbjct: 69 EDYDRLRPLSYPDTDVILMCFSI------DSPDSLE---NIPEKWTPEVKHFCPNVPIIL 119 Query: 116 ISNPVNS 122 + N + Sbjct: 120 VGNKKDL 126 >3SXP-A nrPDB Length = 362 Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 7/31 (22%), Positives = 16/31 (51%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYD 34 + I G +G VG L+ + + +++ + D Sbjct: 13 ILITGGAGFVGSNLAFHFQENHPKAKVVVLD 43 >2O3J-A nrPDB Length = 481 Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 46/130 (35%), Gaps = 25/130 (19%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE------------GIGKDLSHINT 50 KV +GA G VG P ++ + + D+ A+ G D + Sbjct: 11 KVVCVGA-GYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLD-EIVFA 68 Query: 51 NSSCVGYDKDSIENTLSNAQVVLIPAGVP-----RKPGLTRDDLFKMNAGIVKSLVTAVG 105 + I ++ A ++ I P R G+ DL V+S+ + Sbjct: 69 ARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMA-PDL-----KYVESVSRTIA 122 Query: 106 KFAPNARILV 115 ++A +I+V Sbjct: 123 QYAGGPKIVV 132 >5FWK-A nrPDB Length = 727 Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 16/77 (20%) Query: 164 KNPKIGQEQDKTTMHRKVTVIGGH---SGETIIPIITDKSLVFQLDKQY----------- 209 KN K+G +D T R ++ H SG+ + + S + + K Sbjct: 438 KNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQV 497 Query: 210 --EHFIHRVQFGGDEIV 224 F+ RV+ G E+V Sbjct: 498 ANSAFVERVRKRGFEVV 514 >2O23-A nrPDB Length = 265 Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats. Identities = 15/84 (17%), Positives = 28/84 (33%), Gaps = 11/84 (13%) Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSI 62 I G + G+G + L + L D+ E K L + + + + Sbjct: 16 VITGGASGLGLATAERLVGQGASA--VLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 73 Query: 63 ENTLSNA-------QVVLIPAGVP 79 + L+ A V + AG+ Sbjct: 74 QTALALAKGKFGRVDVAVNCAGIA 97 >1QWG-A nrPDB Length = 251 Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 23/66 (34%), Gaps = 10/66 (15%) Query: 67 SNAQVVLIPA-------GVPRKPG---LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116 + A V+I G+ K G D+ N I K + A K A IL Sbjct: 160 AGADYVIIEGRESGKGKGLFDKEGKVKENELDVLAKNVDINKVIFEAPQKSQQVAFILKF 219 Query: 117 SNPVNS 122 + VN Sbjct: 220 GSSVNL 225 >3I83-A nrPDB Length = 320 Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 24/145 (16%), Positives = 47/145 (32%), Gaps = 26/145 (17%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELAL---YDIRAAEGIGKDLSHINTNSSCVGYDKD 60 + ++G +G +G LL + + + Y+ A+GI + + + Sbjct: 5 ILVIG-TGAIGSFYGALLAKTGHCVSVVSRSDYETVKAKGIRIRSATLGDYTFRPAAVVR 63 Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120 S + L+ V G R L + AP+ I++ISN + Sbjct: 64 SAAELETKPDCTLLCIKV--VEGADRVGLLRD-------------AVAPDTGIVLISNGI 108 Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV 145 + +A F V+ Sbjct: 109 DIEPEVAAA-------FPDNEVISG 126 >2X86-A nrPDB Length = 357 Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 10/28 (35%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELA 31 + + G +G +G + L L Sbjct: 49 IIVTGGAGFIGSNIVKALNDKGITDILV 76 >1EQ2-A nrPDB Length = 310 Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 5/28 (17%), Positives = 10/28 (35%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELA 31 + + G +G +G + L L Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILV 29 >3UW3-A nrPDB Length = 377 Score = 28.2 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 12/78 (15%), Positives = 24/78 (30%), Gaps = 7/78 (8%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVS--ELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59 + V ++G G VG L ++ E + A G + + Sbjct: 5 MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKA-----PSFAKNETTLKD 59 Query: 60 DSIENTLSNAQVVLIPAG 77 + + L V++ G Sbjct: 60 ATSIDDLKKCDVIITCQG 77 >6EL3-D nrPDB Length = 381 Score = 28.2 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 43/109 (39%), Gaps = 7/109 (6%) Query: 6 ILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIEN 64 I+G +G VG L+ +L LS +Y + + H C D + + Sbjct: 24 IIGVTGIVGNSLAEILPLSDTPGGPWKVYGVARRPRPTWNADHPIDYIQCDVSDAEDTRS 83 Query: 65 T---LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPN 110 L++ V R + + + N ++++++ A+ +APN Sbjct: 84 KLSPLTDVTHVFYVTWTNR---ESESENCEANGSMLRNVLQAIIPYAPN 129 >2Z2C-A nrPDB Length = 423 Score = 28.2 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 32/184 (17%), Positives = 60/184 (32%), Gaps = 12/184 (6%) Query: 165 NPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIV 224 P + + IG + I + +L++ Y + G IV Sbjct: 98 GPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIV 157 Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284 K G+ M A ++ + E PE + F+ G K + + Sbjct: 158 MDKVSVGATVTIMCAATLAEGTTIIENAARE-PEIVDTANFLITLGAKISGQGTDRIVIE 216 Query: 285 SIEYFS------LPIVLRNGSVVSIDTSVLEKLSPREEQ--LVNTAVKELR---KNIEKG 333 +E LP + G+ + K+ R Q ++ + +LR +IE G Sbjct: 217 GVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG 276 Query: 334 KSFI 337 + +I Sbjct: 277 EDWI 280 >3PWS-A nrPDB Length = 366 Score = 28.2 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 5/74 (6%) Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIE 63 VA++GA+G VG + +L+ S + Y + +A GK L +++ E Sbjct: 5 VAVVGATGAVGAQMIKMLEESTLPIDKIRY-LASARSAGKSLK----FKDQDITIEETTE 59 Query: 64 NTLSNAQVVLIPAG 77 + L AG Sbjct: 60 TAFEGVDIALFSAG 73 >3N58-A nrPDB Length = 464 Score = 28.2 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 30/75 (40%), Gaps = 11/75 (14%) Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62 KVA++ G VG+ + L + ++ D A D G++ ++ Sbjct: 248 KVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMD-----------GFEVVTL 296 Query: 63 ENTLSNAQVVLIPAG 77 ++ S A +V+ G Sbjct: 297 DDAASTADIVVTTTG 311 >1MV8-A nrPDB Length = 436 Score = 27.8 bits (60), Expect = 6.3, Method: Composition-based stats. Identities = 16/94 (17%), Positives = 31/94 (32%), Gaps = 19/94 (20%) Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE--------------GIGKDLSH 47 ++++I G G VG + L + E+ D+ + + G+ L Sbjct: 1 MRISIFGL-GYVGAVCAGCLSARGH--EVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQ 57 Query: 48 INTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRK 81 G + + ++ V I G P K Sbjct: 58 GRQTGRLSG--TTDFKKAVLDSDVSFICVGTPSK 89 >4RFL-A nrPDB Length = 371 Score = 27.8 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 16/116 (13%), Positives = 37/116 (31%), Gaps = 3/116 (2%) Query: 187 HSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAE 246 H II + + E + ++ ++ K F + + Sbjct: 33 HPFTMIIVTPRYTIIEDGAINKIEEILKKLNLKNPLVITGKNTKKYCRF---FYDIVYYD 89 Query: 247 EVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVS 302 E+L + E + + + + G ++ + L I + S+P N + S Sbjct: 90 EILNNLEIELKKYTAYDCVIGIGGGRSIDTGKYLAYKLGIPFISVPTTASNDGIAS 145 >3SQG-A nrPDB Length = 579 Score = 27.8 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 9/36 (25%), Positives = 18/36 (50%) Query: 76 AGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA 111 G+ +K G+ + + + IV S V + + P+A Sbjct: 33 GGIAQKGGMRKREFIAEASKIVDSRVNSTPAYNPDA 68 >3EH7-A nrPDB Length = 434 Score = 27.8 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 36/198 (18%), Positives = 69/198 (34%), Gaps = 8/198 (4%) Query: 38 AEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIV 97 EG + + + + IP P + R D+ ++ IV Sbjct: 66 GEGKYMAPEMAPHFRHITNFVGGNSRKAVEENRADFIPVFFYEVPSMIRKDILHIDVAIV 125 Query: 98 KSLVTAVGKFAPNARILVISNP-VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETF 156 + + + S P S + E ++M N++ ++ LD + Sbjct: 126 QLSMPDENGYCSFGVSCDYSKPAAESAHLVIGEINRQMPYVHGDNLIHISKLDYI----V 181 Query: 157 LVDY--LMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHF-I 213 + DY L PKIG+ ++ + + G + + I I D +L+F DK+ Sbjct: 182 MADYPIYSLAKPKIGEVEEAIGRNCAELIEDGATLQLGIGAIPDAALLFLKDKKDLGIHT 241 Query: 214 HRVQFGGDEIVKAKQGAG 231 G E+V++ G Sbjct: 242 EMFSDGVVELVRSGVITG 259 >4J6F-A nrPDB Length = 382 Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%), Gaps = 8/40 (20%) Query: 4 VAILGASGGVGQPL--------SLLLKLSPYVSELALYDI 35 V + GASGGVG + ++ + ++ E A+ DI Sbjct: 210 VLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDI 249 >4WOJ-A nrPDB Length = 370 Score = 27.4 bits (59), Expect = 8.7, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 12/28 (42%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVS 28 M+KV +G G VG L + S Sbjct: 7 MLKVGFIGWRGMVGSVLMSRMIESKDFD 34 >6QUZ-A nrPDB Length = 587 Score = 27.4 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 17/30 (56%) Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSEL 30 M+ VA++GA GG+G + + ++L Sbjct: 69 MLIVALIGAVGGIGCTVFASYASQNFGADL 98 >3Q98-A nrPDB Length = 399 Score = 27.4 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 15/33 (45%) Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMN 93 S+E +A +V + P K R +L + N Sbjct: 259 SMEEAFKDADIVYPKSWAPYKVMEERTELLRAN 291 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.126 0.315 Lambda K H 0.267 0.0381 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,292,759 Number of Sequences: 36641 Number of extensions: 426771 Number of successful extensions: 2450 Number of sequences better than 10.0: 181 Number of HSP's better than 10.0 without gapping: 167 Number of HSP's successfully gapped in prelim test: 107 Number of HSP's that attempted gapping in prelim test: 1782 Number of HSP's gapped (non-prelim): 288 length of query: 343 length of database: 10,336,785 effective HSP length: 98 effective length of query: 245 effective length of database: 6,745,967 effective search space: 1652761915 effective search space used: 1652761915 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.5 bits) S2: 59 (27.4 bits)