BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P32419
(343 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
5ZI4-A nrPDB 692 0.0
1MLD-A nrPDB 253 7e-68
4WLE-A nrPDB 251 4e-67
1SMK-A nrPDB 238 4e-63
4E0B-A nrPDB 205 3e-53
1IE3-A nrPDB 204 3e-53
6BAL-A nrPDB 186 2e-47
3P7M-A nrPDB 86 2e-17
1HYE-A nrPDB 84 8e-17
4PLW-A nrPDB 84 9e-17
3TL2-A nrPDB 83 1e-16
1UXJ-A nrPDB 83 2e-16
3GVH-A nrPDB 83 2e-16
2HJR-A nrPDB 82 2e-16
4BGV-A nrPDB 82 4e-16
4ROS-A nrPDB 80 1e-15
1GV0-A nrPDB 77 1e-14
1GUZ-A nrPDB 75 5e-14
4PLF-A nrPDB 75 6e-14
1A5Z-A nrPDB 74 6e-14
3NEP-X nrPDB 73 2e-13
3FI9-A nrPDB 71 5e-13
2X0J-A nrPDB 69 3e-12
4L4S-H nrPDB 69 3e-12
1PZF-A nrPDB 67 2e-11
9LDB-A nrPDB 67 2e-11
6H9S-A nrPDB 65 3e-11
5NFR-A nrPDB 65 4e-11
4UUP-A nrPDB 65 5e-11
5NQB-A nrPDB 64 9e-11
6CT6-A nrPDB 64 1e-10
2V65-A nrPDB 64 1e-10
1SOW-A nrPDB 64 1e-10
3ZZN-A nrPDB 63 2e-10
4AJN-A nrPDB 63 2e-10
1Y6J-A nrPDB 63 2e-10
1V6A-A nrPDB 62 4e-10
4LN1-A nrPDB 61 7e-10
2V6B-A nrPDB 60 1e-09
4ND4-A nrPDB 60 1e-09
1LDM-A nrPDB 59 2e-09
1LTH-T nrPDB 59 4e-09
4Q3N-A nrPDB 58 6e-09
4I1I-A nrPDB 58 6e-09
5K0Z-A nrPDB 57 1e-08
1CIV-A nrPDB 57 1e-08
6IHE-A nrPDB 55 5e-08
4M1Q-A nrPDB 54 1e-07
2D4A-B nrPDB 54 1e-07
4KDE-A nrPDB 53 1e-07
1T24-A nrPDB 52 3e-07
6CEP-A nrPDB 52 3e-07
5NUE-A nrPDB 52 4e-07
3D0O-A nrPDB 52 5e-07
5HTO-A nrPDB 51 7e-07
3PQF-A nrPDB 50 1e-06
1OC4-A nrPDB 50 1e-06
5MDH-A nrPDB 50 1e-06
4UUO-A nrPDB 49 2e-06
3WSV-A nrPDB 49 4e-06
6J9S-A nrPDB 48 5e-06
4BGU-A nrPDB 47 2e-05
7MDH-A nrPDB 45 4e-05
4UUM-A nrPDB 45 4e-05
4JCO-A nrPDB 44 1e-04
2LDB-A nrPDB 43 2e-04
1EZ4-A nrPDB 41 8e-04
1B8U-A nrPDB 40 0.001
3DL2-A nrPDB 40 0.002
3D5T-A nrPDB 37 0.010
4TVO-A nrPDB 37 0.018
5ZF1-A nrPDB 33 0.13
4ARE-A nrPDB 30 1.1
2Y6I-A nrPDB 30 1.2
6H1E-A nrPDB 30 1.3
3QB0-A nrPDB 30 1.3
6APE-A nrPDB 30 1.5
5CEF-A nrPDB 29 2.8
2NVK-X nrPDB 29 3.8
2BE7-D nrPDB 28 4.3
4B9V-A nrPDB 28 7.5
3EH7-A nrPDB 28 7.6
1RVY-A nrPDB 27 9.8
>5ZI4-A nrPDB
Length = 345
Score = 692 bits (1786), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60
MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD
Sbjct: 3 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 62
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV
Sbjct: 63 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 122
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK
Sbjct: 123 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 182
Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240
VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA
Sbjct: 183 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 242
Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300
GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV
Sbjct: 243 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 302
Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 343
VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL
Sbjct: 303 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 345
>1MLD-A nrPDB
Length = 314
Score = 253 bits (647), Expect = 7e-68, Method: Compositional matrix adjust.
Identities = 149/340 (43%), Positives = 207/340 (60%), Gaps = 36/340 (10%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61
KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY +
Sbjct: 2 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQ 61
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+ + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P+A I +ISNPVN
Sbjct: 62 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPDAMICIISNPVN 121
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181
S +PI E KK G + P + GVT LD+VRA F+ + L ++ V
Sbjct: 122 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLDPARV-----------SV 170
Query: 182 TVIGGHSGETIIPIITDKS--LVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
VIGGH+G+TIIP+I+ + + F D Q R+Q G E+VKAK GAGSATLSMA+
Sbjct: 171 PVIGGHAGKTIIPLISQCTPKVDFPQD-QLSTLTGRIQEAGTEVVKAKAGAGSATLSMAY 229
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNG 298
AGA+F ++ + + ++ E +FV K+Q+ YFS P++L + G
Sbjct: 230 AGARFVFSLVDAMNGKEGVVE--CSFV---------KSQE----TDCPYFSTPLLLGKKG 274
Query: 299 SVVSIDTSV-LEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
I+ ++ + K+SP EE+++ A+ EL+ +I+KG+ F+
Sbjct: 275 ----IEKNLGIGKISPFEEKMIAEAIPELKASIKKGEEFV 310
>4WLE-A nrPDB
Length = 340
Score = 251 bits (640), Expect = 4e-67, Method: Compositional matrix adjust.
Identities = 149/340 (43%), Positives = 207/340 (60%), Gaps = 36/340 (10%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61
KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY +
Sbjct: 28 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQ 87
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+ + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P A I VI+NPVN
Sbjct: 88 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVN 147
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181
S +PI E KK G + P + GVT LD+VRA TF+ + L ++ V
Sbjct: 148 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARV-----------NV 196
Query: 182 TVIGGHSGETIIPIITDKS--LVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
VIGGH+G+TIIP+I+ + + F D Q R+Q G E+VKAK GAGSATLSMA+
Sbjct: 197 PVIGGHAGKTIIPLISQCTPKVDFPQD-QLTALTGRIQEAGTEVVKAKAGAGSATLSMAY 255
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNG 298
AGA+F ++ + + ++ E +FV K+Q+ YFS P++L + G
Sbjct: 256 AGARFVFSLVDAMNGKEGVVE--CSFV---------KSQE----TECTYFSTPLLLGKKG 300
Query: 299 SVVSIDTSV-LEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
I+ ++ + K+S EE++++ A+ EL+ +I+KG+ F+
Sbjct: 301 ----IEKNLGIGKVSSFEEKMISDAIPELKASIKKGEDFV 336
>1SMK-A nrPDB
Length = 326
Score = 238 bits (606), Expect = 4e-63, Method: Compositional matrix adjust.
Identities = 144/338 (42%), Positives = 204/338 (60%), Gaps = 32/338 (9%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61
KVAILGA+GG+GQPL++L+K++P VS L LYD+ A G+ D+SH++T + G+ +
Sbjct: 10 KVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQ 69
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+E L+ ++++PAGVPRKPG+TRDDLFK+NAGIVK+L + K P A + +ISNPVN
Sbjct: 70 LEAALTGMDLIIVPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPRAIVNLISNPVN 129
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181
S VPIA E KK G + P ++GVT LD+VRA TF+ + L L +P+ V
Sbjct: 130 STVPIAAEVFKKAGTYDPKRLLGVTMLDVVRANTFVAEVLGL-DPR----------DVDV 178
Query: 182 TVIGGHSGETIIPIITD-KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240
V+GGH+G TI+P+++ K ++ + R+Q GG E+V+AK GAGSATLSMA+A
Sbjct: 179 PVVGGHAGVTILPLLSQVKPPSSFTQEEISYLTDRIQNGGTEVVEAKAGAGSATLSMAYA 238
Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNGS 299
KFA+ LR + E AFV + Q+ + +F+ + L RNG
Sbjct: 239 AVKFADACLRGLRGDAGVIE--CAFV----------SSQV---TELPFFASKVRLGRNGI 283
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+ L L+ E + A KEL +IEKG SFI
Sbjct: 284 E---EVYSLGPLNEYERIGLEKAKKELAGSIEKGVSFI 318
>4E0B-A nrPDB
Length = 313
Score = 205 bits (521), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 136/338 (40%), Positives = 193/338 (57%), Gaps = 31/338 (9%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDK 59
+KVA++GA+GG+GQ L+LLLK P S+LALYDI G+ DLSHI T+ S GY
Sbjct: 4 MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTHVSIKGYAG 63
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ L A VVLI AGV RKPG+ R DLF +NAGIVKSL + PNA I +I+NP
Sbjct: 64 EDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACIGIITNP 123
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
VN+ VPIA E LKK G + + GVT LD++R+ETF+ + LK GQ+ +
Sbjct: 124 VNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAE---LK----GQDPGEV---- 172
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
+V VIGGHSG TI+P+++ V D++ R+Q G E+V+AK G GSATLSM
Sbjct: 173 RVPVIGGHSGVTILPLLSQVEGVEFSDEEIAALTKRIQNAGTEVVEAKAGGGSATLSMGQ 232
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
A +F ++++ E+ + + Y+ G NG+ A +F+ P+ L
Sbjct: 233 AACRFGLALVKALQGEE-----VIEYAYVEG--NGEHAS---------FFAQPVKLGKEG 276
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V I +LS E+ ++ ++ L +I+ G F+
Sbjct: 277 VEEILP--YGELSDFEKAALDGMLETLNSDIQIGVDFV 312
>1IE3-A nrPDB
Length = 312
Score = 204 bits (520), Expect = 3e-53, Method: Compositional matrix adjust.
Identities = 134/338 (39%), Positives = 190/338 (56%), Gaps = 30/338 (8%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDK 59
+KVA+LGA+GG+GQ L+LLLK P SEL+LYDI G+ DLSHI T G+
Sbjct: 1 MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSG 60
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ L A VVLI AGV RKPG+ R DLF +NAGIVK+LV V K P A I +I+NP
Sbjct: 61 EDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNP 120
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
VN+ V IA E LKK G + + GVT LD++ + TF+ + LK + G+ +
Sbjct: 121 VNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIICSNTFVAE---LKGKQPGEVE------- 170
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
V VIGGHSG TI+P+++ V +++ R+Q G E+V+AK G GSATLSM
Sbjct: 171 -VPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQ 229
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
A A+F ++R+ E+ E Y+ G +G+ A+ +FS P++L
Sbjct: 230 AAARFGLSLVRALQGEQGVVEC----AYVEG--DGQYAR---------FFSQPLLLGKNG 274
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V + + LS E+ + + L+K+I G+ F+
Sbjct: 275 VE--ERKSIGTLSAFEQNALEGMLDTLKKDIALGQEFV 310
>6BAL-A nrPDB
Length = 335
Score = 186 bits (471), Expect = 2e-47, Method: Compositional matrix adjust.
Identities = 135/338 (39%), Positives = 191/338 (56%), Gaps = 31/338 (9%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDIR-AAEGIGKDLSHINTNSSCVGYDK 59
+KVA+LGA+GG+GQ L+LLLKL P ++L+LYDI G+ D+SHI T + G+
Sbjct: 25 MKVAVLGAAGGIGQALALLLKLQLPAGTDLSLYDIAPVTPGVAVDVSHIPTAVNVKGFSG 84
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ L A VVLI AGV RKPG+ R DLF +NAGIV+ L+ V P A + +I+NP
Sbjct: 85 EDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRGLIEKVAVTCPKACVGIITNP 144
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
VN+ V IA E LKK G + + GVT LD++R+ETF+ + LK G +T+
Sbjct: 145 VNTTVAIAAEVLKKAGVYDKRKLFGVTTLDVLRSETFVAE---LK----GLNVSRTS--- 194
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
V VIGGHSG TI+P+++ + + E R+Q G E++ AK G GSATLSMA
Sbjct: 195 -VPVIGGHSGVTILPLLSQVQYAKWNEDEIEPLTKRIQNAGTEVLNAKAGGGSATLSMAQ 253
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
A A+FA +++ E++ Y+ G +GK A+ +FS P+ L
Sbjct: 254 AAARFARSLVKGLSG-----ETVVECTYVEG--DGKYAR---------FFSQPVRLGKEG 297
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V I + LS E+Q + + LR +IE G+ FI
Sbjct: 298 VEEILP--IGPLSNFEQQALENMLPTLRADIELGEKFI 333
>3P7M-A nrPDB
Length = 321
Score = 86.3 bits (212), Expect = 2e-17, Method: Compositional matrix adjust.
Identities = 85/281 (30%), Positives = 135/281 (48%), Gaps = 36/281 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K+ ++GA G +G L+ L L + ++ L+DI GK L + T G D
Sbjct: 7 KITLVGA-GNIGGTLAHL-ALIKQLGDVVLFDIAQGMPNGKALDLLQT-CPIEGVDFKVR 63
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ L N+ VV++ AGVPRKPG++RDDL +N +++++ + PNA ++ I+N
Sbjct: 64 GTNDYKDLENSDVVIVTAGVPRKPGMSRDDLLGINIKVMQTVGEGIKHNCPNAFVICITN 123
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++ I V L+K ++G+ LD R TFL D L N + Q Q
Sbjct: 124 PLD----IMVNMLQKFSGVPDNKIVGMAGVLDSARFRTFLADEL---NVSVQQVQ----- 171
Query: 178 HRKVTVIGGHSGETIIPIITDKSL----VFQLDKQ-------YEHFIHRVQFGGDEIVKA 226
V+GGH G+T++P+ ++ + QL K+ + + R + GG EIV A
Sbjct: 172 ---AYVMGGH-GDTMVPLTKMSNVAGVSLEQLVKEGKLKQERLDAIVSRTRSGGGEIV-A 226
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVY 267
GSA + A AG + AE L+ P + A +Y
Sbjct: 227 LLKTGSAYYAPAAAGIQMAESFLKDKKMILPCAAKVKAGMY 267
>1HYE-A nrPDB
Length = 313
Score = 84.0 bits (206), Expect = 8e-17, Method: Compositional matrix adjust.
Identities = 82/283 (28%), Positives = 138/283 (48%), Gaps = 44/283 (15%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL----YDIRAAEGIGKDL--SHINTNSSCV 55
+KV I+GASG VG +LLL P++ +L L + I EG+ +D+ + T S
Sbjct: 1 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60
Query: 56 GY-DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
Y + D + + VV+I +GVPRK G++R DL K NA IV + + + +I
Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEIC-DTKIF 119
Query: 115 VISNPVNSLVPIAVETLKKM--GKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQE 171
VI+NPV+ V T K + KF+ V G+ T+LD +R + + + G
Sbjct: 120 VITNPVD------VMTYKALVDSKFERNQVFGLGTHLDSLRFKVAIAKFF-------GVH 166
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHF--------IHRVQFGGDEI 223
D+ + +IG H G++++P+++ S+ +++E F I V+ G++I
Sbjct: 167 IDEV----RTRIIGEH-GDSMVPLLSATSIGGIPIQKFERFKELPIDEIIEDVKTKGEQI 221
Query: 224 VKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFV 266
++ K G+ F A V+R N + +LSA+V
Sbjct: 222 IRLKGGS-------EFGPAAAILNVVRCIVNNEKRLLTLSAYV 257
>4PLW-A nrPDB
Length = 326
Score = 84.0 bits (206), Expect = 9e-17, Method: Compositional matrix adjust.
Identities = 81/281 (28%), Positives = 138/281 (49%), Gaps = 42/281 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56
K++++GA G +G L+ L+ + ++ L+DI GK D+SH + +N G
Sbjct: 6 KISLIGA-GNIGGTLAHLIA-QKELGDVVLFDIVEGMPQGKALDISHSSPIMGSNVKITG 63
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ + + VV+I AG+PRKPG++RDDL +NA I+K + + K+ PNA ++V+
Sbjct: 64 TNN---YEDIKGSDVVIITAGIPRKPGMSRDDLLSVNAKIMKDVAENIKKYCPNAFVIVV 120
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175
+NP++ +V + L K V G+ LD R FL + L + +
Sbjct: 121 TNPLDVMVYV----LHKYSGLPHNKVCGMAGVLDSSRFRYFLAEKLNVSPNDV------- 169
Query: 176 TMHRKVTVIGGHSGETIIPIITDKSL----VFQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231
+ VIGGH G+T++P+ ++ + + KQ +I + + DEIV+ + AG
Sbjct: 170 ----QAMVIGGH-GDTMVPLTRYCTVGGIPLTEFIKQ--GWITQEEI--DEIVERTRNAG 220
Query: 232 SA------TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFV 266
T S FA A A E+ S+ +K SA++
Sbjct: 221 GEIVNLLKTGSAYFAPAASAIEMAESYLKDKKRILPCSAYL 261
>3TL2-A nrPDB
Length = 315
Score = 83.2 bits (204), Expect = 1e-16, Method: Compositional matrix adjust.
Identities = 86/280 (30%), Positives = 132/280 (47%), Gaps = 37/280 (13%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI--GKDLSHINTNSSCVGYDKD 60
KV+++GA G G + LL ++++ L DI E GK L + S G+D +
Sbjct: 10 KVSVIGA-GFTGATTAFLLA-QKELADVVLVDIPQLENPTKGKALDMLEA-SPVQGFDAN 66
Query: 61 SIENT----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
I + +++ VV+I AG+ RKPG++RDDL N+ I+KS+ + K +PNA I+V+
Sbjct: 67 IIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVL 126
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQ 170
+NPV+++ K+ G F V+G + LD R TF+ L L I G
Sbjct: 127 TNPVDAM---TYSVFKEAG-FPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGG 182
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGA 230
D + + GG ET+IP ++ E + R + GG EIV G
Sbjct: 183 HGDDMVPLVRYSYAGGIPLETLIP-----------KERLEAIVERTRKGGGEIV-GLLGN 230
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPG 270
GSA + A + + E +L K + L A YL G
Sbjct: 231 GSAYYAPAASLVEMTEAIL------KDQRRVLPAIAYLEG 264
>1UXJ-A nrPDB
Length = 309
Score = 83.2 bits (204), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 98/348 (28%), Positives = 163/348 (46%), Gaps = 56/348 (16%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI--GKDLSHINTNSSCVGYD-- 58
K++I+GA G VG + L + + ++ L DI EG+ GK L + S G+D
Sbjct: 4 KISIIGA-GFVGSTTAHWLA-AKELGDIVLLDI--VEGVPQGKAL-DLYEASPIEGFDVR 58
Query: 59 ---KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115
++ +T +N+ V+++ +G PRKPG++R+DL K+NA I ++ ++ +PNA I++
Sbjct: 59 VTGTNNYADT-ANSDVIVVTSGAPRKPGMSREDLIKVNADITRACISQAAPLSPNAVIIM 117
Query: 116 ISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDK 174
++NP++++ +A E + F V+G LD R TF I E
Sbjct: 118 VNNPLDAMTYLAAE----VSGFPKERVIGQAGVLDAARYRTF-----------IAMEAGV 162
Query: 175 TTMHRKVTVIGGHSGETI-IPIITDKSLV----FQLDKQYEHFIHRVQFGGDEIVKAKQG 229
+ + ++GGH E + +P + S + F + + R + GG EIV +
Sbjct: 163 SVKDVQAMLMGGHGDEMVPLPRFSTISGIPVSEFIAPDRLAQIVERTRKGGGEIVNLLK- 221
Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYF 289
GSA + A A A+ E VL+ P YL G G N I YF
Sbjct: 222 TGSAYYAPAAATAQMVEAVLKDKKRVMP------VAAYLTG---------QYGLNDI-YF 265
Query: 290 SLPIVLRNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRKNIEKGKSF 336
+P++L G V +LE L+ E L+N + K +R ++ KS
Sbjct: 266 GVPVILGAGGV----EKILELPLNEEEMALLNASAKAVRATLDTLKSL 309
>3GVH-A nrPDB
Length = 324
Score = 82.8 bits (203), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 79/277 (28%), Positives = 133/277 (48%), Gaps = 36/277 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD-KDS 61
K+A++G SG +G L+ L L + ++ L+DI GK L I +S G+D K +
Sbjct: 9 KIALIG-SGMIGGTLAHLAGLKE-LGDVVLFDIAEGTPQGKGLD-IAESSPVDGFDAKFT 65
Query: 62 IEN---TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
N + A VV++ AGVPRKPG++RDDL +N +++ + + K+AP A ++ I+N
Sbjct: 66 GANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITN 125
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++++ V L+K V+G+ LD R FL +E + +
Sbjct: 126 PLDAM----VWALQKFSGLPAHKVVGMAGVLDSARFRYFL-----------SEEFNVSVE 170
Query: 178 HRKVTVIGGHSGETIIPIITDKSLV-----------FQLDKQYEHFIHRVQFGGDEIVKA 226
V V+GGH G++++P+ ++ + + + I R + GG EIV
Sbjct: 171 DVTVFVLGGH-GDSMVPLARYSTVAGIPLPDLVKMGWTSQDKLDKIIQRTRDGGAEIVGL 229
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLS 263
+ GSA + A + + AE L+ P LS
Sbjct: 230 LK-TGSAFYAPAASAIQMAESYLKDKKRVLPVAAQLS 265
>2HJR-A nrPDB
Length = 328
Score = 82.4 bits (202), Expect = 2e-16, Method: Compositional matrix adjust.
Identities = 99/353 (28%), Positives = 163/353 (46%), Gaps = 57/353 (16%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINT--NSSCVGYD 58
K++I+GA G +G ++LLL + ++ ++DI +G DL+H S +
Sbjct: 16 KISIIGA-GQIGSTIALLLGQKD-LGDVYMFDIIEGVPQGKALDLNHCMALIGSPAKIFG 73
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+++ E L N+ VV+I AGVPRKP +TR DL +NA IV S+ VGK+ PNA ++ I+N
Sbjct: 74 ENNYE-YLQNSDVVIITAGVPRKPNMTRSDLLTVNAKIVGSVAENVGKYCPNAFVICITN 132
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++++ V K+ V G++ LD R L L +K +
Sbjct: 133 PLDAM----VYYFKEKSGIPANKVCGMSGVLDSARFRCNLSRALGVKPSDV--------- 179
Query: 178 HRKVTVIGGHSGETIIPIITDKSL--VFQLD---------KQYEHFIHRVQFGGDEIVKA 226
V+GGH G+ +IP+ + ++ + D Q I + FGG EIV+
Sbjct: 180 --SAIVVGGH-GDEMIPLTSSVTIGGILLSDFVEQGKITHSQINEIIKKTAFGGGEIVEL 236
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286
+ GSA + A + A+ L K L YL G N
Sbjct: 237 LK-TGSAFYAPAASAVAMAQAYL------KDSKSVLVCSTYLTGQYNVNNL--------- 280
Query: 287 EYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338
+ +P+V+ +NG I+ V+ LS E+ L + +V+ ++ ++ KS L
Sbjct: 281 -FVGVPVVIGKNG----IEDVVIVNLSDDEKSLFSKSVESIQNLVQDLKSLNL 328
>4BGV-A nrPDB
Length = 323
Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust.
Identities = 77/280 (27%), Positives = 136/280 (48%), Gaps = 40/280 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD-- 60
K++++GA G VG ++ L + ++ ++DI GK L I + GYD D
Sbjct: 4 KISVIGA-GAVGATVAQTLAIRQ-TGDIYIFDIVDGLAEGKALD-ILEGAPHWGYDLDIK 60
Query: 61 -------SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARI 113
S + + V+++ AG+ RKPG++RDDL N GI+KS+ A+ K++P ++I
Sbjct: 61 GFCTADESKYAEMKGSDVIVVTAGLARKPGMSRDDLLLKNIGIMKSVGEAIKKYSPESKI 120
Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQ 172
+V++NP + I + K P ++G+ +LD R TFL QE
Sbjct: 121 VVVTNPAD----IMAYAIYKASGISPERIIGLGGSLDSTRFRTFL-----------AQEL 165
Query: 173 DKTTMHRKVTVIGGHSGETIIPII--TDKSLVFQLD----KQYEHFIHRVQFGGDEIVKA 226
+ + VIGGH G+ ++P I ++ S + D ++ + + R +FGG EIV
Sbjct: 166 NVSFEDVNAFVIGGH-GDDMVPFIRYSNVSGIPIEDLLPREKIDEIVKRTRFGGGEIVNL 224
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFV 266
+ GSA + + A E ++ N++ +A++
Sbjct: 225 YK-TGSAFYAPGISIAVMVESIV----NDRKRVIPCAAYI 259
>4ROS-A nrPDB
Length = 320
Score = 80.5 bits (197), Expect = 1e-15, Method: Compositional matrix adjust.
Identities = 81/296 (27%), Positives = 139/296 (46%), Gaps = 28/296 (9%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD-- 60
K+A++GA G +G L+ L L + ++ L+DI GK L I ++ G+D
Sbjct: 5 KIALIGA-GQIGGTLAHLAGLKE-LGDVVLFDIVDGVPQGKALD-IAESAPVDGFDAKYS 61
Query: 61 --SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
S + ++ A VV++ AGVPRKPG++RDDL +N +++++ + + AP+A ++ I+N
Sbjct: 62 GASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGAGIKEHAPDAFVICITN 121
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI------GQE 171
P++++ V L+K V+G+ LD R FL + + + G
Sbjct: 122 PLDAM----VWALQKFSGLPTNKVVGMAGVLDSARFRHFLAEEFGVSVEDVTAFVLGGHG 177
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231
D + R TV G +P+ L + ++ + + R + GG EIV + G
Sbjct: 178 DDMVPLTRYSTVAG-------VPLTDLVKLGWTTQEKLDAMVERTRKGGGEIVNLLK-TG 229
Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE 287
SA + A + AE LR P L + GL G ++G+N +E
Sbjct: 230 SAFYAPAASAIAMAESYLRDKKRVLPCAAYLDGQYGIDGLYVG--VPVVIGENGVE 283
>1GV0-A nrPDB
Length = 310
Score = 77.0 bits (188), Expect = 1e-14, Method: Compositional matrix adjust.
Identities = 79/261 (30%), Positives = 129/261 (49%), Gaps = 34/261 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+K+ ++GA G VG + L EL L D+ EGI + + S VG
Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDV--VEGIPQGKALDMYESGPVGLFDTK 57
Query: 62 IENT-----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ + +N+ +V+I AG+PRKPG+TR+DL MNAGIV+ + + + + N I+V+
Sbjct: 58 VTGSNDYADTANSDIVVITAGLPRKPGMTREDLLSMNAGIVREVTGRIMEHSKNPIIVVV 117
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175
SNP++ + +A +K G K V+G+ LD R +F+ L + QD T
Sbjct: 118 SNPLDIMTHVA---WQKSGLPKE-RVIGMAGVLDSARFRSFIAMELGVSM------QDVT 167
Query: 176 TMHRKVTVIGGHSGETIIPIITDKSL----VFQL--DKQYEHFIHRVQFGGDEIVKA-KQ 228
V+GGH G+ ++P++ ++ V L ++ + R + GG EIV KQ
Sbjct: 168 A-----CVLGGH-GDAMVPVVKYTTVAGIPVADLISAERIAELVERTRTGGAEIVNHLKQ 221
Query: 229 GAGSATLSMAFAGAKFAEEVL 249
GSA S A + + E ++
Sbjct: 222 --GSAFYSPATSVVEMVESIV 240
>1GUZ-A nrPDB
Length = 310
Score = 75.1 bits (183), Expect = 5e-14, Method: Compositional matrix adjust.
Identities = 84/327 (25%), Positives = 149/327 (45%), Gaps = 40/327 (12%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+K+ ++GA G VG + L EL L D+ EGI + + S VG
Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDV--VEGIPQGKALDMYESGPVGLFDTK 57
Query: 62 IENT-----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ + +N+ +V+I AG+PRKPG+TR+DL NAGIVK + + K + N I+V+
Sbjct: 58 VTGSNDYADTANSDIVIITAGLPRKPGMTREDLLMKNAGIVKEVTDNIMKHSKNPIIIVV 117
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
SNP++ + +A + K + + GV LD R +F I E +
Sbjct: 118 SNPLDIMTHVA-WVRSGLPKERVIGMAGV--LDAARFRSF-----------IAMELGVSM 163
Query: 177 MHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKA-KQG 229
V+GGH G+ ++P++ ++ + + + R + GG EIV+ KQ
Sbjct: 164 QDINACVLGGH-GDAMVPVVKYTTVAGIPISDLLPAETIDKLVERTRNGGAEIVEHLKQ- 221
Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSA-------FVYLPGLKNGKKAQQLVG 282
GSA + A + + E ++ P L FV +P +K G+ + +
Sbjct: 222 -GSAFYAPASSVVEMVESIVLDRKRVLPCAVGLEGQYGIDKTFVGVP-VKLGRNGVEQIY 279
Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLE 309
+ +++ L ++ ++ +V + +LE
Sbjct: 280 EINLDQADLDLLQKSAKIVDENCKMLE 306
>4PLF-A nrPDB
Length = 334
Score = 74.7 bits (182), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 97/347 (27%), Positives = 162/347 (46%), Gaps = 60/347 (17%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH----INTNSSCVG 56
K++++G SG +G ++ L + ++ L+D+ +G DLSH +TN G
Sbjct: 10 KISLIG-SGMIGGTMAYLCA-QKELGDVVLFDVVKNMPQGKALDLSHSSSIADTNVKVTG 67
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111
+S E+ + + VV+I AG+ + PG +RDDL NA I++ + + K+ PNA
Sbjct: 68 --TNSYED-IKGSDVVIITAGLTKAPGKSDKEWSRDDLLPFNAKIMREVGENIKKYCPNA 124
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPK---- 167
++VI+NP++ +V + E + K K + GV LD R F+ + L + +P+
Sbjct: 125 FVIVITNPLDVMVKVLHEH-SGLPKNKVCGMAGV--LDSSRFRHFIAEKLNV-SPRDVQA 180
Query: 168 --IGQEQDKTT-MHRKVTVIGGHSGETIIPI--ITDKSLVFQLDKQYEHFIHRVQFGGDE 222
IG DK + R VTV G IP+ K + Q ++ + + R + G E
Sbjct: 181 MVIGAHGDKMVPLTRYVTVNG-------IPLQEFIKKGRITQ--EEIDEIVERTKNAGGE 231
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
IV G GSA + A + + AE L K + L YL G K
Sbjct: 232 IVNL-LGQGSAYFAPAASAIEMAEAYL------KDKKRVLVCSCYLEGQYGHKDM----- 279
Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRK 328
+ +P V+ V V+E +L+P E++L + +V+E+RK
Sbjct: 280 -----FVGVPAVIGGNGV----EKVIELELTPEEKELFDKSVEEVRK 317
>1A5Z-A nrPDB
Length = 319
Score = 74.3 bits (181), Expect = 6e-14, Method: Compositional matrix adjust.
Identities = 83/279 (29%), Positives = 131/279 (46%), Gaps = 36/279 (12%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHIN--TNSSCVGY 57
+K+ I+G G VG + L + + E+ L D+ + AEG DL H T + + Y
Sbjct: 1 MKIGIVGL-GRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANI-Y 58
Query: 58 DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
D + L + VV++ AGVP+KPG TR L NA ++K + V K+AP++ ++V++
Sbjct: 59 AGDYAD--LKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVT 116
Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPK------IGQ 170
NPV+ L LK+ G P V G T LD R T + + +P+ IG+
Sbjct: 117 NPVDVLTYF---FLKESG-MDPRKVFGSGTVLDTARLRTLIAQHCGF-SPRSVHVYVIGE 171
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLD-KQYEHFIHRVQFGGDEIVKAKQG 229
D +IGG IP+ + + D K E+F + + EI++ K
Sbjct: 172 HGDSEVPVWSGAMIGG------IPLQNMCQVCQKCDSKILENFAEKTKRAAYEIIERK-- 223
Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYL 268
G+ ++A A A E + F +EK L+ VYL
Sbjct: 224 -GATHYAIALAVADIVESI---FFDEK---RVLTLSVYL 255
>3NEP-X nrPDB
Length = 314
Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust.
Identities = 66/235 (28%), Positives = 113/235 (48%), Gaps = 31/235 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+KV ++GA G VG ++ + E+ + DI+ GK L + +S G+D
Sbjct: 1 MKVTVIGA-GNVGATVAECVARQDVAKEVVMVDIKDGMPQGKALD-MRESSPIHGFDT-R 57
Query: 62 IENT-----LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ T ++ V +I AG+PR PG++RDDL N IV + + +P++ I+V+
Sbjct: 58 VTGTNDYGPTEDSDVCIITAGLPRSPGMSRDDLLAKNTEIVGGVTEQFVEGSPDSTIIVV 117
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175
+NP++ + +A E F VMG+ LD R +F I +E D +
Sbjct: 118 ANPLDVMTYVAYEA----SGFPTNRVMGMAGVLDTGRFRSF-----------IAEELDVS 162
Query: 176 TMHRKVTVIGGHSGETIIPIITDKSL----VFQL--DKQYEHFIHRVQFGGDEIV 224
+ ++GGH G+T++P+ ++ V QL D + E + R + G EIV
Sbjct: 163 VRDVQALLMGGH-GDTMVPLPRYTTVGGIPVPQLIDDARIEEIVERTKGAGGEIV 216
>3FI9-A nrPDB
Length = 343
Score = 71.2 bits (173), Expect = 5e-13, Method: Compositional matrix adjust.
Identities = 61/237 (25%), Positives = 110/237 (46%), Gaps = 26/237 (10%)
Query: 3 KVAILGASGGVGQPLS---LLLKLSPYVSELALYDIRAA--EGIGKDLSHINTNSSCVGY 57
K+ I+GA+G +G ++ +++L+P L LYD A EG+ +++ H + +
Sbjct: 10 KLTIVGAAGMIGSNMAQTAAMMRLTP---NLCLYDPFAVGLEGVAEEIRHCGFEGLNLTF 66
Query: 58 DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNAR-ILVI 116
D I+ L++A+ ++ G PRK G+TR+DL K NA I L + + P+ + +++I
Sbjct: 67 TSD-IKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIII 125
Query: 117 SNP--VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDK 174
NP + LV + L KP V + LD R ++ L + +K + +
Sbjct: 126 FNPADITGLVTLIYSGL------KPSQVTTLAGLDSTRLQSELAKHFGIKQSLVTNTRTY 179
Query: 175 TTMHRKVTVIGGHSGETIIPII----TDKSLVFQLDKQYEHFIHRVQFGGDEIVKAK 227
++ V + P+ TDK ++Q+ RV GG I+K +
Sbjct: 180 GGHGEQMAVFASTAKVNGTPLTDLIGTDK----LTNEQWAELKQRVVKGGANIIKLR 232
>2X0J-A nrPDB
Length = 294
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 71/235 (30%), Positives = 114/235 (48%), Gaps = 35/235 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCV 55
+K+ +GA G VG + L+ V E+AL DI +G+ DL+H I+ V
Sbjct: 1 MKLGFVGA-GRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIV 59
Query: 56 GYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115
G S+ L ++++++ AG+ RKPG+TR DL NAGI+K + + + AP ++ILV
Sbjct: 60 GGADYSL---LKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILV 116
Query: 116 ISNPVNSLVPIAVETLKKMGKFKPGN-VMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173
++NP++ + I K+ G KP N V G+ N LD R + L +
Sbjct: 117 VTNPMDVMTYI---MWKESG--KPRNEVFGMGNQLDSQRLKERLYNA------------- 158
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLV-FQLDKQYEHFIHRVQFGGDEIVKAK 227
R+ +IG H + KSL F + +E + V+F E++K K
Sbjct: 159 GARNIRRAWIIGEHGDSMFVA----KSLADFDGEVDWEAVENDVRFVAAEVIKRK 209
>4L4S-H nrPDB
Length = 339
Score = 68.9 bits (167), Expect = 3e-12, Method: Compositional matrix adjust.
Identities = 72/269 (26%), Positives = 124/269 (46%), Gaps = 32/269 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH----INTNSSCVG 56
K+ ++G G VG ++ + + ELAL D+ +G DL H + T G
Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSG 79
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
D N +N+++V+I AG ++ G +R +L + N I K ++ V K++PN ++L++
Sbjct: 80 KDY----NVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIV 135
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQ 170
SNPV+ L +A K+ F V+G NLD R E V L +G+
Sbjct: 136 SNPVDILTYVAW----KISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGE 191
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPII-TDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQ 228
D + + G S +T+ P + TDK DK+ +H+ V E++K K
Sbjct: 192 HGDSSVPVWSGMNVAGVSLKTLHPDLGTDK------DKEQWKEVHKQVVESAYEVIKLK- 244
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKP 257
G + ++ + A AE ++++ P
Sbjct: 245 --GYTSWAIGLSVADLAESIMKNLRRVHP 271
>1PZF-A nrPDB
Length = 331
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 67/247 (27%), Positives = 113/247 (45%), Gaps = 45/247 (18%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHI----NTNSSCVG 56
KVA++G SG +G + L L ++++ LYD+ EG DLSH+ +TN S
Sbjct: 11 KVAMIG-SGMIGGTMGYLCALRE-LADVVLYDVVKGMPEGKALDLSHVTSVVDTNVSVRA 68
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111
+ S E L+ A V++ AG+ + PG +R+DL N+ I++ + + K+ P
Sbjct: 69 --EYSYEAALTGADCVIVTAGLTKVPGKPDSEWSRNDLLPFNSKIIREIGQNIKKYCPKT 126
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMG--VTNLDLVRAETFLVDYLMLKNPKIG 169
I+V++NP++ +V + E P N++ LD R ++ D L + +
Sbjct: 127 FIIVVTNPLDCMVKVMCEA-----SGVPTNMICGMACMLDSGRFRRYVADALSVSPRDV- 180
Query: 170 QEQDKTTMHRKVTVIGGHSGETIIPI---ITDKSLVFQ--------LDKQYEHFIHRVQF 218
+ TVIG H G+ ++P+ IT Q +KQ E +
Sbjct: 181 ----------QATVIGTH-GDCMVPLVRYITVNGYPIQKFIKDGVVTEKQLEEIAEHTKV 229
Query: 219 GGDEIVK 225
G EIV+
Sbjct: 230 SGGEIVR 236
>9LDB-A nrPDB
Length = 332
Score = 66.6 bits (161), Expect = 2e-11, Method: Compositional matrix adjust.
Identities = 84/335 (25%), Positives = 152/335 (45%), Gaps = 64/335 (19%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56
K+ ++G G VG ++ + + E+AL D+ + G+ DL H + T G
Sbjct: 22 KITVVGV-GAVGMACAISILMKELADEIALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
D N +N+++V+I AG ++ G +R +L + N I K ++ + K++PN ++LV+
Sbjct: 81 KDY----NVTANSRLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCKLLVV 136
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKT 175
SNPV+ L +A K+ F V+G NLD R YLM G+
Sbjct: 137 SNPVDILTYVA----WKISGFPKNRVIGSGCNLDSARFR-----YLM------GERLGVH 181
Query: 176 TMHRKVTVIGGHSGETIIPI--------ITDKSLVFQL----DKQYEHFIHR-VQFGGDE 222
+ ++G H G++ +P+ ++ K+L +L DK++ +H+ V E
Sbjct: 182 PLSCHGWILGEH-GDSSVPVWSGVNVAGVSLKNLHPELGTDADKEHWKAVHKEVVDSAYE 240
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
++K K G + ++ + A AE ++++ P + + L G+K
Sbjct: 241 VIKLK---GYTSWAIGLSVADLAESIMKNLRRVHPISTMIKG---LYGIKENV------- 287
Query: 283 DNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREE 316
+ S+P +L +NG I V L+P EE
Sbjct: 288 -----FLSVPCILGQNG----ISDVVKVTLTPEEE 313
>6H9S-A nrPDB
Length = 307
Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 60/198 (30%), Positives = 93/198 (46%), Gaps = 24/198 (12%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDK 59
+K++I+G +G VG + L + E+ LYD+ AEG DL H T + K
Sbjct: 1 MKISIIG-TGRVGSSTAFALINAAVADEIVLYDLNKEMAEGEALDLLHATT------FHK 53
Query: 60 DSI-----ENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
I + + + +VLI AG +KPG TR DL NA I+K + + K+APN I+
Sbjct: 54 RMIIRAGEYSDIEGSDIVLITAGAAQKPGETRLDLTIKNAKIIKGISENIKKYAPNTLII 113
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFL-----VDYLMLKNPKI 168
I+NPV+ + + + K+ F+ V+G T LD R + V + + I
Sbjct: 114 NITNPVDVMSYV----VWKVTGFESNRVIGTGTILDTARLRALIGKNCGVSPMSVHAYII 169
Query: 169 GQEQDKTTMHRKVTVIGG 186
G+ D +IGG
Sbjct: 170 GEHGDSELAAWSSAMIGG 187
>5NFR-A nrPDB
Length = 320
Score = 65.1 bits (157), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 59/202 (29%), Positives = 101/202 (50%), Gaps = 28/202 (13%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHINT----NSSC 54
M K+A++G SG +G + L L + +L LYD+ +G DL H +T N +
Sbjct: 1 MTKIALIG-SGQIGAIVGELCLLEN-LGDLILYDVVPGIPQGKALDLKHFSTILGVNRNI 58
Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+G ++ IE+ + +A +++I AGV RK G+TR+DL +N I+KS+ +V A ++
Sbjct: 59 LGTNQ--IED-IKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVI 115
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173
+SNP++ I V K + G+ LD R + + D L K+ E
Sbjct: 116 CVSNPLD----IMVNVFHKFSNLPHEKICGMAGILDTSRYCSLIADKL-----KVSAED- 165
Query: 174 KTTMHRKVTVIGGHSGETIIPI 195
++GGH G+ ++P+
Sbjct: 166 -----VNAVILGGH-GDLMVPL 181
>4UUP-A nrPDB
Length = 341
Score = 65.1 bits (157), Expect = 5e-11, Method: Compositional matrix adjust.
Identities = 67/246 (27%), Positives = 106/246 (43%), Gaps = 34/246 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE----LALYDI----RAAEGIGKDLSHINTNSS 53
+ V I GA+G +G L+ + + L L +I +A EG+ +L +
Sbjct: 5 IHVLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTL 64
Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNAR 112
D E + V + PRKPG+ R DL + NAGI K A+ ++A P +
Sbjct: 65 AGVVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVK 124
Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172
+LV+ NP N+ IA+ K+G P N +T LD RA + K+G
Sbjct: 125 VLVVGNPANTNCLIAMANAPKLG---PENFSAMTRLDHNRAIGEIA-------AKLGVPV 174
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITD---------KSLVFQLDKQY--EHFIHRVQFGGD 221
DK V V G HS T +P ++ K + L K+Y F+ ++ G
Sbjct: 175 DKV---HNVVVWGNHS-NTQVPDVSHATVDKEGGTKKVSDALPKEYLEGEFVQKIAQRGG 230
Query: 222 EIVKAK 227
+++A+
Sbjct: 231 AVIEAR 236
>5NQB-A nrPDB
Length = 332
Score = 63.9 bits (154), Expect = 9e-11, Method: Compositional matrix adjust.
Identities = 69/268 (25%), Positives = 122/268 (45%), Gaps = 30/268 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56
K+ ++G G VG ++ + + ELAL D+ + G+ DL H + T G
Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
D + +N+++V+I AG ++ G +R +L + N I K ++ V K++P+ ++LV+
Sbjct: 81 KDY----SVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPHCKLLVV 136
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQ 170
SNPV+ L +A K+ F V+G NLD R E V L +G+
Sbjct: 137 SNPVDILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWILGE 192
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQG 229
D + + G S +T+ P L DK+ +H+ V E++K K
Sbjct: 193 HGDSSVPVWSGMNVAGVSLKTLHP-----ELGTDADKEQWKQVHKQVVDSAYEVIKLK-- 245
Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKP 257
G + ++ + A AE ++++ P
Sbjct: 246 -GYTSWAIGLSVADLAESIMKNLRRVHP 272
>6CT6-A nrPDB
Length = 338
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 78/268 (29%), Positives = 129/268 (48%), Gaps = 39/268 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVG---- 56
K+A++G SG +G ++ L L + ++ L+D+ +GK DL H NSS V
Sbjct: 11 KIALVG-SGMIGGTMAFLCSLKE-LGDVVLFDVVPNMPMGKAMDLCH---NSSVVDNGIT 65
Query: 57 -YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPN 110
Y +S E L+NA VV+I AG+ + PG +R DL +N I++ + A+ K+ PN
Sbjct: 66 VYGSNSYE-CLTNADVVIITAGITKIPGKSDKEWSRMDLLPVNIKIMREVGGAIKKYCPN 124
Query: 111 ARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLM-----LKN 165
A I+ I+NP++ +V AV+ + K + G+ LD R + D L ++
Sbjct: 125 AFIINITNPLDVMVA-AVQEAANVPKHMICGMAGM--LDSSRLRRMIADCLHVSPHDVQG 181
Query: 166 PKIGQEQDKTT-MHRKVTVIGGHSGETIIPI--ITDKSLVFQLDKQYEHFIHRVQFGGDE 222
IG D + R +T+ G IPI +K L+ + D + ++ + G +
Sbjct: 182 MVIGVHGDNMLPLMRYITING-------IPIQEFINKGLINKED--INNIYNKTKQAGGD 232
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLR 250
IV+ G GSA + + AE L+
Sbjct: 233 IVRL-LGQGSAYYAPGTSAILMAESYLK 259
>2V65-A nrPDB
Length = 331
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 84/324 (25%), Positives = 152/324 (46%), Gaps = 59/324 (18%)
Query: 17 LSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYDKDSIENTLSNAQVV 72
+S+LLK ELA+ D+ + G+ DL H + + VG DKD + +N++VV
Sbjct: 37 ISILLK--DLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIVG-DKDY--SVTANSKVV 91
Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132
++ AG ++ G +R +L + N I K ++ + K++PN ++V+SNPV+ L +A
Sbjct: 92 VVTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVA----W 147
Query: 133 KMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGET 191
K+ F V+G TNLD R + + L L +P ++ H ++G H G++
Sbjct: 148 KLSGFPRHRVIGSGTNLDSARFRHLIGEKLHL-HP--------SSCH--AWIVGEH-GDS 195
Query: 192 IIPI--------ITDKSLVFQL----DKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMA 238
+P+ ++ + L Q+ D + IH+ V G E++K K G + ++
Sbjct: 196 SVPVWSGVNVAGVSLQGLNPQMGTEGDGENWKAIHKEVVDGAYEVIKLK---GYTSWAIG 252
Query: 239 FAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNG 298
+ A E ++++ H P +S V Q + G + S+P VL N
Sbjct: 253 MSVADLVESIIKNMHKVHP----VSTLV-----------QGMHGVKDEVFLSVPCVLGNS 297
Query: 299 SVVSIDTSVLEKLSPREEQLVNTA 322
+ + L+ + E+QL +A
Sbjct: 298 GLTDVIHMTLK--AEEEKQLQKSA 319
>1SOW-A nrPDB
Length = 328
Score = 63.5 bits (153), Expect = 1e-10, Method: Compositional matrix adjust.
Identities = 74/291 (25%), Positives = 127/291 (43%), Gaps = 51/291 (17%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDL------SHINTNSSCVG 56
K+A++G SG +G + L L ++++ L+D+ GK L S +TN S
Sbjct: 10 KIAMIG-SGMIGGTMGYLCVLRE-LADVVLFDVVTGMPEGKALDDSQATSIADTNVSVTS 67
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111
++ ++ + VV+I AG+ + PG +R+DL NA I++ + V K+ P A
Sbjct: 68 ANQ---YEKIAGSDVVIITAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKYCPLA 124
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQ 170
++V++NP++ + V+ + V G+ N LD R F+ D L + I
Sbjct: 125 FVIVVTNPLDCM----VKCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPRDI-- 178
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPI---ITDKSLVFQ--------LDKQYEHFIHRVQFG 219
+ TVIG H G+ ++P+ +T + + + + R +
Sbjct: 179 ---------QATVIGTH-GDHMLPLARYVTVNGFPLREFIKKGKMTEAKLAEIVERTKKA 228
Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPG 270
G EIV+ G GSA + A + A+ L K E L VY G
Sbjct: 229 GGEIVRL-LGQGSAYYAPALSAITMAQAFL------KDEKRVLPCSVYCQG 272
>3ZZN-A nrPDB
Length = 310
Score = 63.2 bits (152), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 57/193 (29%), Positives = 89/193 (46%), Gaps = 14/193 (7%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDK 59
+KV I+G SG VG + L L E+ L D+ + A+ +D+ H + V
Sbjct: 1 MKVGIVG-SGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWA 59
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
S + L A+ V++ AGV ++PG TR L NA + +V V + AP A +LV +NP
Sbjct: 60 GSYGD-LEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNP 118
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKI-----GQEQD 173
V+ + +A + PG V+G T LD R L +YL + + G+ D
Sbjct: 119 VDVMTQVA----YALSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGD 174
Query: 174 KTTMHRKVTVIGG 186
+ +GG
Sbjct: 175 SEVLVWSSAQVGG 187
>4AJN-A nrPDB
Length = 331
Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 71/273 (26%), Positives = 128/273 (46%), Gaps = 40/273 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH--INTNSSCVGYD 58
K+ ++G G VG ++ + + ELAL D+ +G DL H + + +
Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSS 79
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
KD + +N+++V+I AG ++ G +R +L + N I K ++ V K++P ++L++SN
Sbjct: 80 KDY--SVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSN 137
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
PV+ L +A K+ F V+G NLD R YLM G+ +
Sbjct: 138 PVDILTYVA----WKISGFPKNRVIGSGCNLDSARFR-----YLM------GERLGVHPL 182
Query: 178 HRKVTVIGGHSGETIIPI--------ITDKSLVFQL----DKQYEHFIHR-VQFGGDEIV 224
V+G H G++ +P+ ++ KSL QL DK+ +H+ V E++
Sbjct: 183 SCHGWVLGEH-GDSSVPVWSGVNVAGVSLKSLNPQLGTDADKEQWKDVHKQVVDSAYEVI 241
Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKP 257
K K G + ++ + A AE ++++ P
Sbjct: 242 KLK---GYTSWAIGLSVADLAESIMKNLRRVHP 271
>1Y6J-A nrPDB
Length = 318
Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust.
Identities = 75/259 (28%), Positives = 116/259 (44%), Gaps = 25/259 (9%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG----YD 58
KVAI+GA G VG + + L +EL L D+ + IG+ + IN +G Y
Sbjct: 9 KVAIIGA-GFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMD-INHGLPFMGQMSLYA 66
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
D + + + V+++ AG RKPG TR DL K N I K + + K+ + ILV+SN
Sbjct: 67 GDY--SDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSN 124
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQEQ 172
PV+ I ++K G V+G T LD +R +E VD + IG+
Sbjct: 125 PVD----IITYMIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNVHGYIIGEHG 180
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232
D T I +G+ I I D F ++ + V+ G I+K K G+
Sbjct: 181 DSQLPLWSCTHI---AGKNINEYIDDPKCNFT-EEDKKKIAEDVKTAGATIIKNK---GA 233
Query: 233 ATLSMAFAGAKFAEEVLRS 251
+A + E +L++
Sbjct: 234 TYYGIAVSINTIVETLLKN 252
>1V6A-A nrPDB
Length = 332
Score = 62.0 bits (149), Expect = 4e-10, Method: Compositional matrix adjust.
Identities = 84/324 (25%), Positives = 147/324 (45%), Gaps = 58/324 (17%)
Query: 17 LSLLLKLSPYVSELALYDIRA--AEGIGKDLSH--INTNSSCVGYDKDSIENTLSNAQVV 72
+S+LLK ELAL D+ +G DL H + + + DKD + +N++VV
Sbjct: 37 ISILLK--DLTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDY--SVTANSKVV 92
Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132
++ AG ++ G +R +L + N I K ++ + K++PN +LV+SNPV+ L +A
Sbjct: 93 VVTAGARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVAW---- 148
Query: 133 KMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGET 191
K+ V+G TNLD R + L K+G + H VIG H G++
Sbjct: 149 KLSGLPRNRVIGSGTNLDSAR-------FRHLMGEKLGIH--PSNCHG--WVIGEH-GDS 196
Query: 192 IIPIITDKSL--VF----------QLDKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMA 238
+P+ + ++ VF DK+ +H+ V E++K K G + ++
Sbjct: 197 SVPVWSGVNVAGVFLQGLNPDMGTDKDKEDWKSVHKMVVDSAYEVIKLK---GYTSWAIG 253
Query: 239 FAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNG 298
+ A + +L++ P +S V + + G N + S+P +L N
Sbjct: 254 MSAADLCQSILKNLRKCHP----VSTLV-----------KGMHGVNEEVFLSVPCILGNS 298
Query: 299 SVVSIDTSVLEKLSPREEQLVNTA 322
+ + L+ S E+QLV +A
Sbjct: 299 GLTDVVHMTLK--SDEEKQLVKSA 320
>4LN1-A nrPDB
Length = 336
Score = 61.2 bits (147), Expect = 7e-10, Method: Compositional matrix adjust.
Identities = 89/342 (26%), Positives = 148/342 (43%), Gaps = 57/342 (16%)
Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSH-INTNSSCVGYDKDSI 62
+L +G VG + + E L D+ A EG DLSH + + K S
Sbjct: 31 VLVGTGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWKGSY 90
Query: 63 ENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNS 122
E+ +A +V+I AG+P+KPG TR DL + NA I K +V ++ + L+ +NPV+
Sbjct: 91 EDC-KDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPVDI 149
Query: 123 LVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVT 182
L + T K+ G K + T LD R L +Y IG H
Sbjct: 150 LTYV---TWKESGLPKERVIGSGTTLDSARFRYMLGEYF-----DIGP-------HNIHA 194
Query: 183 VIGGHSGETIIPIITDKSL-------VFQLDKQYEH------FIHRVQFGGDEIVKAKQG 229
I G G+T +P+ + S+ + + D Y FI+ V+ I++ ++G
Sbjct: 195 YIIGEHGDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFIN-VRDAAYHIIE-RKG 252
Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYF 289
A + M+ V ++ N++ ++SA++ G+ Q+ V Y
Sbjct: 253 ATYYGIGMSLL------RVTKAILNDENSVLTVSAYL------EGQYGQKDV------YI 294
Query: 290 SLPIVLRNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRKNI 330
+P VL G V +LE +LS EE + +V+ L++ +
Sbjct: 295 GVPAVLNRGGV----REILEVELSEDEELKFDHSVQVLKETM 332
>2V6B-A nrPDB
Length = 304
Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 49/173 (28%), Positives = 81/173 (46%), Gaps = 7/173 (4%)
Query: 18 SLLLKLSPYVSELALYDIRA--AEGIGKDLSHIN--TNSSCVGYDKDSIENTLSNAQVVL 73
+ L L SEL L D A+ +D++H ++ + V + S L++AQVV+
Sbjct: 16 AFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVWHGGHS---ELADAQVVI 72
Query: 74 IPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKK 133
+ AG +KPG +R DL + NA I + LV + + AP+A +LV SNPV+ L +A +
Sbjct: 73 LTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVDLLTDLATQLAPG 132
Query: 134 MGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGG 186
G V+ + A+ VD +G+ D + ++ G
Sbjct: 133 QPVIGSGTVLDSARFRHLMAQHAGVDGTHAHGYVLGEHGDSEVLAWSSAMVAG 185
>4ND4-A nrPDB
Length = 321
Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust.
Identities = 57/208 (27%), Positives = 103/208 (49%), Gaps = 32/208 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI--GK--DLSH----INTNSSC 54
K+A++G SG +G ++ ++ ++++ L+DI AEGI GK D++H + S
Sbjct: 6 KIAVIG-SGQIGGNIAYIVG-KDNLADVVLFDI--AEGIPQGKALDITHSMVMFGSTSKV 61
Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+G + + +S + VV+I A +P +P R +L NA I+ S+ V K+ PNA ++
Sbjct: 62 IGTNDYA---DISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKYCPNAFVI 118
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173
I+NP++ + V +K+ V G+ LD R TF+ + + +
Sbjct: 119 CITNPLD----VMVSHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQHFGVNASDV----- 169
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSL 201
VIGGH G+ ++P + S+
Sbjct: 170 ------SANVIGGH-GDGMVPATSSVSV 190
>1LDM-A nrPDB
Length = 329
Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust.
Identities = 87/351 (24%), Positives = 154/351 (43%), Gaps = 60/351 (17%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH----INTNSSCVG 56
K+ ++G G VG ++ + + E+AL D+ + G+ DL H ++T G
Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG 80
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
D + + +++V+I AG ++ G +R +L + N I K ++ + K +P+ ILV+
Sbjct: 81 KD----YSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVV 136
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKT 175
SNPV+ L +A K+ ++G NLD R YLM G+
Sbjct: 137 SNPVDVLTYVAW----KLSGLPMHRIIGSGCNLDSARFR-----YLM------GERLGVH 181
Query: 176 TMHRKVTVIGGHSGETIIPIITDKSLV---------FQLDKQYEHFIHR-VQFGGDEIVK 225
+ VIG H G+++ + + ++ DKQ +H+ V E++K
Sbjct: 182 SCSCHGWVIGEH-GDSVPSVWSGMNVASIKLHPLDGTNKDKQDWKKLHKDVVDSAYEVIK 240
Query: 226 AKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNS 285
K G + ++ + A AE ++++ P + + F G+K DN
Sbjct: 241 LK---GYTSWAIGLSVADLAETIMKNLCRVHPVSTMVKDFY---GIK----------DNV 284
Query: 286 IEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+ SLP VL + + +I V KL P EEQ + + L +I+K F
Sbjct: 285 --FLSLPCVLNDHGISNI---VKMKLKPNEEQQLQKSATTLW-DIQKDLKF 329
>1LTH-T nrPDB
Length = 319
Score = 58.5 bits (140), Expect = 4e-09, Method: Compositional matrix adjust.
Identities = 74/273 (27%), Positives = 115/273 (42%), Gaps = 23/273 (8%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60
K+A++GA G VG L+ E+ L DI E D+ H ++ V D
Sbjct: 9 KLAVIGA-GAVGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDGS 67
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+A +V+I AG +KPG +R +L I+K+++ + K APNA ++I+NPV
Sbjct: 68 DDPEICRDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNPV 127
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPK------IGQEQD 173
+ IA +K+ + G TNLD R FL+ N K G+ D
Sbjct: 128 D----IATHVAQKLTGLPENQIFGSGTNLDSARLR-FLIAQQTGVNVKNVHAYIAGEHGD 182
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGS 232
+ IGG P+ L DK+ E IH+ V+ +I+ K G+
Sbjct: 183 SEVPLWESATIGGVPMSDWTPLPGHDPL--DADKREE--IHQEVKNAAYKIINGK---GA 235
Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAF 265
++ +G E VL + P + L F
Sbjct: 236 TNYAIGMSGVDIIEAVLHDTNRILPVSSMLKDF 268
>4Q3N-A nrPDB
Length = 314
Score = 57.8 bits (138), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 89/321 (27%), Positives = 134/321 (41%), Gaps = 54/321 (16%)
Query: 27 VSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKDSIE----NTLSNAQVVLIPAGVPR 80
V EL L DI R AEG DL+H G K SI+ +A +V+I AGV +
Sbjct: 28 VEELVLLDIDKRKAEGEAMDLNH----GLAFGPRKMSIKAGDYKDCKDAGLVVITAGVNQ 83
Query: 81 KPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPG 140
K G TR L K NA I+K++V + N +LV SNPV+ L +A K+ G
Sbjct: 84 KEGETRIHLLKRNAEIIKTVVKNIMSSGFNGILLVASNPVDVLAYVA---WKESGLHHSR 140
Query: 141 NVMGVTNLDLVRAETFLVDYLMLKNPKI-----GQEQDKTTMHRKVTVIGGHSGETIIPI 195
+ T+LD R + Y+ + + + G+ D + +G +I
Sbjct: 141 VIGSGTSLDTARLRYEISQYIHIDSRNVHAYILGEHGDSEFVCWSNANVGAKPIADVIDS 200
Query: 196 ITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ----GAGSATLSMAFAGAKFAEEVLRS 251
+ + S + EH +V+ EI+ K+ G G A + + A
Sbjct: 201 MDEISF-----EDLEHIYLKVRDAAYEIISRKKATYYGIGMALVRITAA----------I 245
Query: 252 FHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE-YFSLPIVLRNGSVVSIDTSVLEK 310
F+NE + + + L NG V D + Y LP VL V I V K
Sbjct: 246 FNNE-------NRILPISVLNNG------VYDCEDQVYIGLPAVLNKDGVHHI---VKLK 289
Query: 311 LSPREEQLVNTAVKELRKNIE 331
L+ +E +N + LRKN++
Sbjct: 290 LNEKENSQLNNSANILRKNLD 310
>4I1I-A nrPDB
Length = 345
Score = 57.8 bits (138), Expect = 6e-09, Method: Compositional matrix adjust.
Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 50/253 (19%)
Query: 2 VKVAILGASGGVGQPLSLLLK----LSPYVS-ELALYDI----RAAEGIGKDLSH----- 47
VKVA+ GA+G +G L L+ L P EL L DI +A G+ +L
Sbjct: 25 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 84
Query: 48 ----INTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTA 103
+ T V +D + ++ PRK G+ R DL +MNA I K A
Sbjct: 85 LDKVVVTADPRVAFD---------GVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEA 135
Query: 104 VGKFAP-NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLM 162
+ A + R++V+ NP N+ I +++ + GK P +V +T LD RA + L
Sbjct: 136 IAAVAASDCRVVVVGNPANTNALILLKSAQ--GKLNPRHVTAMTRLDHNRALSLLARKAG 193
Query: 163 LKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLV--------FQLDKQYEHFIH 214
+ ++ R V + G HS T +P TD +++ + D + F+
Sbjct: 194 VPVSQV----------RNVIIWGNHS-STQVP-DTDSAVIGTTPAREAIKDDALDDDFVQ 241
Query: 215 RVQFGGDEIVKAK 227
V+ G EI++ +
Sbjct: 242 VVRGRGAEIIQLR 254
>5K0Z-A nrPDB
Length = 331
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 76/315 (24%), Positives = 137/315 (43%), Gaps = 47/315 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYD 58
K+ ++G G VG ++ + ELAL D+ + G+ DL H + + + D
Sbjct: 21 KITVVGV-GQVGMACAISILGKGLCDELALVDVLEDKLKGEMMDLQHGSLFLQTHKIVAD 79
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
KD +N+++V++ AGV ++ G +R +L + N + K ++ + K++PN ILV+SN
Sbjct: 80 KDYA--VTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPNCTILVVSN 137
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPK-----IGQEQD 173
PV+ L + T K G K + NLD R + + L + +G+ D
Sbjct: 138 PVDILTYV---TWKLSGLPKHRVIGSGCNLDTARFRYLMAERLGIHPTSCHGWILGEHGD 194
Query: 174 KTTMHRKVTVIGGHSGETIIPII-TDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAG 231
+ + G S + + P + TDK D + +H+ V E+++ K G
Sbjct: 195 SSVAVWSGVNVAGVSLQELNPAMGTDK------DSENWKEVHKQVVESAYEVIRLK---G 245
Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE---Y 288
++ + A+ E +L++ + S+S V G IE +
Sbjct: 246 YTNWAIGLSVAELCETMLKNLY----RVHSVSTLVK--------------GTYGIENDVF 287
Query: 289 FSLPIVLRNGSVVSI 303
SLP VL + S+
Sbjct: 288 LSLPCVLSASGLTSV 302
>1CIV-A nrPDB
Length = 385
Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust.
Identities = 57/214 (26%), Positives = 92/214 (42%), Gaps = 29/214 (13%)
Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARILVISNPVNSLV 124
+A+ L+ PR PG+ R DL +N I A+ A PN +++V+ NP N+
Sbjct: 116 FQDAEWALLIGAKPRGPGMERADLLDINGQIFAEQGKALNAVASPNVKVMVVGNPCNT-- 173
Query: 125 PIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI 184
A+ LK P N +T LD RA+ L K G DK + VT+
Sbjct: 174 -NALICLKNAPNIPPKNFHALTRLDENRAKCQLA-------LKAGVFYDKVS---NVTIW 222
Query: 185 GGHSGETIIPIITDK------SLVFQLDKQY--EHFIHRVQFGGDEIVKAKQGAGSATLS 236
G HS + + K + V + D+++ + F + VQ G ++K + +A+ +
Sbjct: 223 GNHSTTQVPDFLNAKIHGIPVTEVIR-DRKWLEDEFTNMVQTRGGVLIKKWGRSSAASTA 281
Query: 237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPG 270
++ A +RS PE + S VY G
Sbjct: 282 VSIVDA------IRSLVTPTPEGDWFSTGVYTNG 309
>6IHE-A nrPDB
Length = 303
Score = 55.1 bits (131), Expect = 5e-08, Method: Compositional matrix adjust.
Identities = 42/138 (30%), Positives = 73/138 (52%), Gaps = 10/138 (7%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHI----NTNSSCVG 56
KV +GA G +GQ ++ +S V E +YDI + +L H ++ +G
Sbjct: 2 KVGFIGA-GKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFATKGIKANVLG 60
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+S+++ +S +V+I AG PRKPG++R DLF NA I+ L + P A L++
Sbjct: 61 --TNSLDD-VSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKLPSKNPGAIYLMV 117
Query: 117 SNPVNSLVPIAVETLKKM 134
+NPV+ + + ++ K+
Sbjct: 118 ANPVDMMASVFMKYSKQF 135
>4M1Q-A nrPDB
Length = 339
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 58/198 (29%), Positives = 86/198 (43%), Gaps = 21/198 (10%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSH-INTNSSCVGYDK 59
+V I+G +G VG + + E+ L D+ R EG DL+H I + +
Sbjct: 29 RVVIIG-TGAVGSSYAFSMINQNVTDEMVLIDLDKRKTEGDAMDLNHGIPFGAPTKVWAG 87
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
D +A +V+I AG +KPG TR DL + NA I K +V V N ++ +NP
Sbjct: 88 DY--GDCKSADIVVITAGAAQKPGETRLDLVEKNANIFKGIVDQVMGSGFNGIFIIATNP 145
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
V+ L A T K G K + T LD R L +Y + D +H
Sbjct: 146 VDVL---AYATWKFSGLPKERVIGSGTILDTARFRFLLSEYF---------DIDVRNIH- 192
Query: 180 KVTVIGGHSGETIIPIIT 197
I G G+T +P+ +
Sbjct: 193 --GYIMGEHGDTELPVWS 208
>2D4A-B nrPDB
Length = 308
Score = 53.9 bits (128), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 46/161 (28%), Positives = 83/161 (51%), Gaps = 16/161 (9%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRA-AEGIGKDLSHINTNSSCVGYD---- 58
+ ILGA G VG +++L + Y L + +G DL+H ++ +G D
Sbjct: 2 ITILGA-GKVGMATAVMLMMRGYDDLLLIARTPGKPQGEALDLAH---AAAELGVDIRIS 57
Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
+S E+ + + +VL+ AG+ RKPG+TR+ L + NA + L + +A +A +++ +
Sbjct: 58 GSNSYED-MRGSDIVLVTAGIGRKPGMTREQLLEANANTMADLAEKIKAYAKDAIVVITT 116
Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFL 157
NPV+++ + KK G F V+G + LD R ++
Sbjct: 117 NPVDAMTYV---MYKKTG-FPRERVIGFSGILDSARMAYYI 153
>4KDE-A nrPDB
Length = 341
Score = 53.1 bits (126), Expect = 1e-07, Method: Compositional matrix adjust.
Identities = 59/205 (28%), Positives = 88/205 (42%), Gaps = 28/205 (13%)
Query: 2 VKVAILGASGGVGQPL-------SLLLKLSPYVSELALYDI----RAAEGIGKDLSHINT 50
V+VA+ GA+G +G L +L K P + L L +I +A EG+ +L
Sbjct: 5 VRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVI--LQLLEIPQAMKALEGVVMELEDCAF 62
Query: 51 NSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-P 109
D + +A L+ PRK G+ R DL ++N I A+ + A
Sbjct: 63 PLLAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKK 122
Query: 110 NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIG 169
+ ++LV+ NP N+ IA K P N +T LD RA+ L K G
Sbjct: 123 DVKVLVVGNPANTNALIA---YKNAPGLNPRNFTAMTRLDHNRAKAQLAK-------KTG 172
Query: 170 QEQDKTTMHRKVTVIGGHSGETIIP 194
D+ R++TV G HS T+ P
Sbjct: 173 TGVDRI---RRMTVWGNHS-STMFP 193
>1T24-A nrPDB
Length = 322
Score = 52.4 bits (124), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 41/127 (32%), Positives = 65/127 (51%), Gaps = 9/127 (7%)
Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIENT 65
+L SG +G ++ L+ + + ++ L+DI GK L +TN K S NT
Sbjct: 8 VLVGSGMIGGVMATLI-VQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNT 66
Query: 66 ---LSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
L+ A VV++ AG + PG RDDL +N I+ + + K PNA I+V++
Sbjct: 67 YDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFIIVVT 126
Query: 118 NPVNSLV 124
NPV+ +V
Sbjct: 127 NPVDVMV 133
>6CEP-A nrPDB
Length = 334
Score = 52.0 bits (123), Expect = 3e-07, Method: Compositional matrix adjust.
Identities = 45/163 (27%), Positives = 83/163 (50%), Gaps = 10/163 (6%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYD 58
K+ ++G G VG ++ + ELAL D+ + G+ DL H + + + D
Sbjct: 23 KITVVGV-GQVGMACAISILGKSLTDELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
KD + +N+++V++ AGV ++ G +R +L + N + K ++ + K++P+ I+V+SN
Sbjct: 82 KDY--SVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSN 139
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYL 161
PV+ L + T K G K + NLD R + + L
Sbjct: 140 PVDILTYV---TWKLSGLPKHRVIGSGCNLDSARFRYLMAEKL 179
>5NUE-A nrPDB
Length = 332
Score = 51.6 bits (122), Expect = 4e-07, Method: Compositional matrix adjust.
Identities = 71/277 (25%), Positives = 117/277 (42%), Gaps = 39/277 (14%)
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARILVISN 118
D++E + V ++ G PRK G+ R D+ N I KS A+ K A PN ++LV++N
Sbjct: 74 DAVEGC-TGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNCKVLVVAN 132
Query: 119 PVNSLVPIAVETLKKMGKFKP-GNVMGVTNLDLVRA-----ETFLVDYLMLKNPKI---- 168
P N+ I LK+ P N+ +T LD RA E V +KN I
Sbjct: 133 PANTNALI----LKEFAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDVKNVIIWGNH 188
Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228
Q H KV G + + ++ D + LD + FI VQ G I+KA++
Sbjct: 189 SSSQYPDVNHAKVQTSSGE--KPVRELVKDDAW---LDGE---FISTVQQRGAAIIKARK 240
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
+ + + + + + +R + PE +S VY G +
Sbjct: 241 LSSALSAASSAC------DHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGL---------I 285
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKE 325
+S P+ RNG + ++++S ++ L +KE
Sbjct: 286 YSFPVTCRNGDWSIVQGLPIDEVSRKKMDLTAEELKE 322
>3D0O-A nrPDB
Length = 317
Score = 51.6 bits (122), Expect = 5e-07, Method: Compositional matrix adjust.
Identities = 82/310 (26%), Positives = 123/310 (39%), Gaps = 49/310 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVGYDKD 60
KV ++G +G VG + L V EL + D+ + G DL H S K
Sbjct: 8 KVVLIG-NGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKA 66
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ +A +V+I AG +KPG TR DL N I KS+V V + LV +NPV
Sbjct: 67 GEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPV 126
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
+ L A T K G K + T LD R L + D
Sbjct: 127 DIL---AYATWKFSGLPKERVIGSGTILDSARFRLLLSEAF-----------DVAPRSVD 172
Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDK-----------QYEHFIHRVQFGGDEIVKAKQG 229
+IG H G+T +P+ + ++ Q K Q E + + +I++AK
Sbjct: 173 AQIIGEH-GDTELPVWSHANIAGQPLKTLLEQRPEGKAQIEQIFVQTRDAAYDIIQAK-- 229
Query: 230 AGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYF 289
G+ +A A+ E + F NE A + + L G+ ++ V Y
Sbjct: 230 -GATYYGVAMGLARITEAI---FRNE-------DAVLTVSALLEGEYEEEDV------YI 272
Query: 290 SLPIVL-RNG 298
+P V+ RNG
Sbjct: 273 GVPAVINRNG 282
>5HTO-A nrPDB
Length = 346
Score = 51.2 bits (121), Expect = 7e-07, Method: Compositional matrix adjust.
Identities = 38/133 (28%), Positives = 68/133 (51%), Gaps = 11/133 (8%)
Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHIN--TNSSCVGYDKDS 61
+L SG +G ++ L+ + + ++ ++D+ +G D SH N S+C +S
Sbjct: 38 VLVGSGMIGGVMATLI-VQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTGSNS 96
Query: 62 IENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
++ L A VV++ AG + PG RDDL +N I+ + + PNA I+V+
Sbjct: 97 YDD-LKGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFIIVV 155
Query: 117 SNPVNSLVPIAVE 129
+NPV+ +V + E
Sbjct: 156 TNPVDVMVQLLFE 168
>3PQF-A nrPDB
Length = 326
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 84/334 (25%), Positives = 135/334 (40%), Gaps = 51/334 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVGYDKD 60
KVA++GA G VG + L EL + D+ + +G DL+H +
Sbjct: 7 KVALIGA-GFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLNHGKAFAPQPVKTSY 65
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+A +V I AG +KPG TR +L + N I K +V+ V + LV +NPV
Sbjct: 66 GTYEDCKDADIVCICAGANQKPGETRLELVEKNLKIFKGIVSEVMASGFDGIFLVATNPV 125
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
+ L T K G K + T LD R L +Y G H
Sbjct: 126 DILT---YATWKFSGLPKERVIGSGTTLDSARFRFMLSEYF-------GAAPQNVCAH-- 173
Query: 181 VTVIGGHSGETIIPIITDKS--------LVFQLD----KQYEHFIHRVQFGGDEIVKAKQ 228
+IG H G+T +P+ + + LV + D ++ + + V+ I++ K
Sbjct: 174 --IIGEH-GDTELPVWSHANVGGVPVSELVEKNDAYKQEELDQIVDDVKNAAYHIIEKK- 229
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
G+ +A + A+ + +L HN E L+ YL G Q D+ Y
Sbjct: 230 --GATYYGVAMSLARITKAIL---HN---ENSILTVSTYLDG--------QYGADDV--Y 271
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTA 322
+P V+ G + I L + +EQ +++A
Sbjct: 272 IGVPAVVNRGGIAGITELNLNE--KEKEQFLHSA 303
>1OC4-A nrPDB
Length = 322
Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 39/127 (30%), Positives = 64/127 (50%), Gaps = 9/127 (7%)
Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIENT 65
+L SG +G ++ L+ + + ++ ++DI GK L +TN K S NT
Sbjct: 8 VLVGSGMIGGVMATLI-VQKNLGDVVMFDIVKNMPHGKALDTSHTNVMAYSNCKVSGSNT 66
Query: 66 ---LSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
L +A VV++ AG + PG RDDL +N I+ + + PNA I+V++
Sbjct: 67 YDDLKDADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNNCPNAFIIVVT 126
Query: 118 NPVNSLV 124
NPV+ +V
Sbjct: 127 NPVDVMV 133
>5MDH-A nrPDB
Length = 333
Score = 50.1 bits (118), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 72/296 (24%), Positives = 125/296 (42%), Gaps = 46/296 (15%)
Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA-RI 113
+ DK+ I + V ++ +PR+ G+ R DL K N I K A+ K+A + ++
Sbjct: 68 IATDKEEI--AFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSVKV 125
Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQD 173
+V+ NP N+ A ++ + K N +T LD RA+ + K+G D
Sbjct: 126 IVVGNPANTNCLTASKSAPSIPK---ENFSCLTRLDHNRAKAQIA-------LKLGVTSD 175
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDK--QYE----------HFIHRVQFGGD 221
+ V + G HS T P + + Q + YE FI VQ G
Sbjct: 176 DV---KNVIIWGNHSS-TQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQRGA 231
Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281
++KA++ LS A + AK + +R PE E +S + G G V
Sbjct: 232 AVIKARK------LSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYG------V 279
Query: 282 GDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
D+ + +S P+ +++ + ++ + S RE+ ++ KEL + E F+
Sbjct: 280 PDDLL--YSFPVTIKDKTWKIVEGLPINDFS-REK--MDLTAKELAEEKETAFEFL 330
>4UUO-A nrPDB
Length = 340
Score = 49.3 bits (116), Expect = 2e-06, Method: Compositional matrix adjust.
Identities = 52/210 (24%), Positives = 85/210 (40%), Gaps = 25/210 (11%)
Query: 2 VKVAILGASGGVGQPLSLLL---------KLSPYVSELALYDIRAAEGIGKDLSHINTNS 52
+ + I GA+G +G L+ + K+ ++ E+ + ++A EG +L +
Sbjct: 4 IHILITGAAGQIGYALTFRIAKGDLCGDRKVVLHLLEIP-FGMKALEGCVMELQDCAFPN 62
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNA 111
D +E V + PRK G+ R DL N GI A+ +A P
Sbjct: 63 VAGIVWTDKVEEAFKGVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALNDYAKPTV 122
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171
++LV+ NP N+ IA + K+ + N +T LD R L + KI
Sbjct: 123 KVLVVGNPANTNCLIAQASAPKL---QNKNWCAMTRLDHNRMVGALAAKFGVTPEKI--- 176
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSL 201
KV + G HS T +P T ++
Sbjct: 177 -------HKVCIWGNHS-NTQVPDTTHATV 198
>3WSV-A nrPDB
Length = 322
Score = 48.5 bits (114), Expect = 4e-06, Method: Compositional matrix adjust.
Identities = 58/193 (30%), Positives = 85/193 (44%), Gaps = 15/193 (7%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDL-SHINTNSSCVGYDK 59
KV I+G +G VG ++ + +EL L D+ AEG DL + V
Sbjct: 7 KVVIVG-TGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNVSVWS 65
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ E +A +V++ AGV +KPG TR DL K NA I + +V V + +V SNP
Sbjct: 66 GTYEE-CQDANLVILTAGVNQKPGQTRLDLVKTNATITRQIVKEVMASGFDGIFVVASNP 124
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVR-----AETFLVDYLMLKNPKIGQEQD 173
V+ L + T ++ G V+G T LD R A VD + +G+ D
Sbjct: 125 VDILTYL---TWQESG-LPASRVVGTGTTLDTTRFRKEIALKLAVDPRSVHGYILGEHGD 180
Query: 174 KTTMHRKVTVIGG 186
T +GG
Sbjct: 181 SEVAAWSHTTVGG 193
>6J9S-A nrPDB
Length = 326
Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 74/277 (26%), Positives = 116/277 (41%), Gaps = 57/277 (20%)
Query: 68 NAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIA 127
+A +V+I AG P+KPG TR DL N I+KS+V + N LV +NPV+ I
Sbjct: 76 DADLVVITAGAPQKPGETRLDLVNKNLKILKSIVDPIVDSGFNGIFLVAANPVD----IL 131
Query: 128 VETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGG 186
K+ F V+G T+LD R + + + D ++H I G
Sbjct: 132 TYATWKLSGFPKNRVVGSGTSLDTARFRQSIAKMVNV---------DARSVH---AYIMG 179
Query: 187 HSGETIIPIITDKSL-------------VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233
G+T P+ + ++ + DK + F V+ EI+K K G+
Sbjct: 180 EHGDTEFPVWSHANIGGVTIAEWVKAHPEIKEDKLVKMF-EDVRNKAYEIIKLK---GAT 235
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+A A A+ ++ +L E L VY+ G G N I Y P
Sbjct: 236 FYGIATALARISKAILND------ENAVLPLSVYMDG---------QYGLNDI-YIGTPA 279
Query: 294 VL-RNGSVVSIDTSVLE-KLSPREEQLVNTAVKELRK 328
V+ RNG ++LE L+ EE+ + + +L+K
Sbjct: 280 VINRNGI-----QNILEIPLTDHEEESMQKSASQLKK 311
>4BGU-A nrPDB
Length = 303
Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 33/109 (30%), Positives = 55/109 (50%), Gaps = 9/109 (8%)
Query: 21 LKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI------ENTLSNAQVVLI 74
L L EL DI E K + + + YD +++ E+T + + VV+I
Sbjct: 20 LALRDVCDELVFVDIPKMED--KTVGQAADTNHGIAYDSNTVVTQGGYEDT-AGSDVVVI 76
Query: 75 PAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSL 123
AG+PR+PG TR DL NA I+ + +++ ++ + + SNPV+ L
Sbjct: 77 TAGIPRQPGQTRIDLAGDNAPIMDDIGSSLAEYNDDFVSITTSNPVDLL 125
>7MDH-A nrPDB
Length = 375
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 66/269 (24%), Positives = 107/269 (39%), Gaps = 43/269 (15%)
Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NARILVISNPVNSLV 124
+ L+ PR PG+ R L +N I A+ A N ++LV+ NP N+
Sbjct: 106 FEDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASKNVKVLVVGNPCNT-- 163
Query: 125 PIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI 184
A+ LK N +T LD RA+ L K G DK + VT+
Sbjct: 164 -NALICLKNAPDIPAKNFHALTRLDENRAKCQLA-------LKAGVFYDKVS---NVTIW 212
Query: 185 GGHSGETIIPIITD--------KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLS 236
G HS T +P + K ++ + E F VQ G +++ + +A+ +
Sbjct: 213 GNHS-TTQVPDFLNAKIDGRPVKEVIKRTKWLEEEFTITVQKRGGALIQKWGRSSAASTA 271
Query: 237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLR 296
++ A A ++S PE + S VY G G A+ +V FS+P +
Sbjct: 272 VSIADA------IKSLVTPTPEGDWFSTGVYTTGNPYG-IAEDIV-------FSMPCRSK 317
Query: 297 N------GSVVSIDTSVLEKLSPREEQLV 319
+ VS D + E++ E +L+
Sbjct: 318 GDGDYELATDVSNDDFLWERIKKSEAELL 346
>4UUM-A nrPDB
Length = 341
Score = 45.4 bits (106), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 4/89 (4%)
Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARILVISNPVNSLV 124
+ + A +P KPG R DL N+ I K+ + K+A P+ ++LVI NP N+
Sbjct: 77 FKDIDCAFLVASMPLKPGQVRADLISSNSVIFKNTGEYLSKWAKPSVKVLVIGNPDNTNC 136
Query: 125 PIAVETLKKMGKFKPGNVMGVTNLDLVRA 153
IA+ K + KP N ++ LD RA
Sbjct: 137 EIAMLHAKNL---KPENFSSLSMLDQNRA 162
>4JCO-A nrPDB
Length = 304
Score = 43.9 bits (102), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 28/75 (37%), Positives = 43/75 (57%), Gaps = 6/75 (8%)
Query: 49 NTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA 108
NT GY E+T + + VV+I AG+PR+PG TR DL NA I++ + +++ +
Sbjct: 58 NTRVRQGGY-----EDT-AGSDVVVITAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHN 111
Query: 109 PNARILVISNPVNSL 123
+ L SNPV+ L
Sbjct: 112 DDYISLTTSNPVDLL 126
>2LDB-A nrPDB
Length = 317
Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust.
Identities = 82/327 (25%), Positives = 127/327 (38%), Gaps = 56/327 (17%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSH--INTNSSCVGYD 58
+V ++GA G VG L E+ L D ++ IG D +H + +
Sbjct: 8 RVVVIGA-GFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPVDIWH 66
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
D + +A +V+I AG +KPG TR DL N I +S+V +V LV +N
Sbjct: 67 GDY--DDCRDADLVVICAGANQKPGETRLDLVDKNIAIFRSIVESVMASGFQGLFLVATN 124
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMH 178
PV+ L T K G + T LD R L +Y + +
Sbjct: 125 PVDILT---YATWKFSGLPHERVIGSGTILDTARFRFLLGEYFSVAPQNV---------- 171
Query: 179 RKVTVIGGHSGETIIPIITD--------KSLV----FQLDKQYEHFIHRVQFGGDEIVKA 226
+IG H G+T +P+ + + LV + K E V+ +I++
Sbjct: 172 -HAYIIGEH-GDTELPVWSQAYIGVMPIRKLVESKGEEAQKDLERIFVNVRDAAYQIIEK 229
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286
K G+ +A A+ +L HNE L+ YL GL +
Sbjct: 230 K---GATYYGIAMGLARVTRAIL---HNENA---ILTVSAYLDGLYGERDV--------- 271
Query: 287 EYFSLPIVL-RNG--SVVSIDTSVLEK 310
Y +P V+ RNG V+ I+ + EK
Sbjct: 272 -YIGVPAVINRNGIREVIEIELNDDEK 297
>1EZ4-A nrPDB
Length = 318
Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust.
Identities = 23/56 (41%), Positives = 33/56 (58%)
Query: 68 NAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSL 123
+A +V+I AG P+KPG +R DL N I+ S+V V + LV +NPV+ L
Sbjct: 72 DADLVVITAGAPQKPGESRLDLVNKNLNILSSIVKPVVDSGFDGIFLVAANPVDIL 127
>1B8U-A nrPDB
Length = 329
Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 23/66 (34%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Query: 66 LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NARILVISNPVNSLV 124
+A V L+ PR PG+ R DL + NA I A+ A N ++LV+ NP N+
Sbjct: 81 FKDADVALLVGARPRGPGMERKDLLEANAQIFTVQGKAIDAVASRNIKVLVVGNPANTNA 140
Query: 125 PIAVET 130
IA+++
Sbjct: 141 YIAMKS 146
>3DL2-A nrPDB
Length = 303
Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 61/249 (24%), Positives = 109/249 (43%), Gaps = 47/249 (18%)
Query: 88 DLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGV-T 146
D+ + N + ++LV A+G ++ ++ +LV S PV + + K+ F V+G+
Sbjct: 96 DVVQSNVDMFRALVPALGHYSQHSVLLVASQPVEIMTYVT----WKLSTFPANRVIGIGC 151
Query: 147 NLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLD 206
NLD R + + + +LK G+E V VI G GE DK L +
Sbjct: 152 NLDSQRLQYIITN--VLKAQTSGKE---------VWVI-GEQGE-------DKVLTWSGQ 192
Query: 207 KQYEHFIHRVQFGGD--EIVKAK-QGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLS 263
++ +VQ E+++ K Q + S LS+A +++ S N K + S+S
Sbjct: 193 EEVVSHTSQVQLSNRAMELLRVKGQRSWSVGLSVA--------DMVDSIVNNKKKVHSVS 244
Query: 264 AFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTA 322
A A+ NS + SLP +L NG I T++ E + Q ++
Sbjct: 245 AL-----------AKGYYDINSEVFLSLPCILGTNGVSEVIKTTLKEDTVTEKLQSSASS 293
Query: 323 VKELRKNIE 331
+ L++ ++
Sbjct: 294 IHSLQQQLK 302
>3D5T-A nrPDB
Length = 331
Score = 37.4 bits (85), Expect = 0.010, Method: Compositional matrix adjust.
Identities = 46/182 (25%), Positives = 73/182 (40%), Gaps = 33/182 (18%)
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NARILVISN 118
D + +A V L+ PR G+ R DL NA I A+ + A + ++LV+ N
Sbjct: 77 DDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGAALNEVASRDVKVLVVGN 136
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMH 178
P N+ IA+++ + K N + LD RA + L +
Sbjct: 137 PANTNAYIAMKSAPDLPK---KNFTAMLRLDHNRALSQLA----------AKSGKPVASI 183
Query: 179 RKVTVIGGHS-------------GETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVK 225
K+ V G HS GE+++ +I D V+ D FI V G I++
Sbjct: 184 EKLAVWGNHSPTMYPDFRFATAEGESLLKLINDD--VWNRDT----FIPTVGKRGAAIIE 237
Query: 226 AK 227
A+
Sbjct: 238 AR 239
>4TVO-A nrPDB
Length = 330
Score = 36.6 bits (83), Expect = 0.018, Method: Compositional matrix adjust.
Identities = 65/260 (25%), Positives = 103/260 (39%), Gaps = 64/260 (24%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS---------PYVSELALYDI----RAAEGIGKDLSHI 48
+KVA+ GA+G +G SLL +L+ P EL L +I +A EG+ +L
Sbjct: 6 LKVAVTGAAGQIG--YSLLFRLASGSLLGPDRPI--ELRLLEIEPALQALEGVVMELDDC 61
Query: 49 N---TNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVG 105
+ +G D I + +S + L+ PR G+ R DL + N I + A+
Sbjct: 62 AFPLLSGVEIGSDPQKIFDGVS---LALLVGARPRGAGMERSDLLEANGAIFTAQGKALN 118
Query: 106 KFAP-NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLK 164
A + R+ V NP N+ IA +TN + E F +
Sbjct: 119 AVAADDVRVGVTGNPANTNALIA-----------------MTNAPDIPRERFSALTRLDH 161
Query: 165 NPKIGQEQDKT----TMHRKVTVIGGHS-------------GETIIPIITDKSLVFQLDK 207
N I Q KT T +K+T+ G HS G+ ++ D++ +
Sbjct: 162 NRAISQLAAKTGAAVTDIKKMTIWGNHSATQYPDLFHAEVAGKNAAEVVNDQAWI----- 216
Query: 208 QYEHFIHRVQFGGDEIVKAK 227
+ FI V G I+ A+
Sbjct: 217 -EDEFIPTVAKRGAAIIDAR 235
>5ZF1-A nrPDB
Length = 301
Score = 33.5 bits (75), Expect = 0.13, Method: Compositional matrix adjust.
Identities = 27/98 (27%), Positives = 45/98 (45%), Gaps = 18/98 (18%)
Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD-KDSIEN 64
++G S VG P++++L D R G+G D T + C Y KD +E
Sbjct: 163 VIGRSKNVGMPIAMMLH----------SDKRHESGLGMDA----TVTICHRYTPKDKLEA 208
Query: 65 TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT 102
NA +++ G+P+ L + D+ K A I+ +T
Sbjct: 209 YCRNADIIITATGLPK---LIKADMVKPGATIIDVGIT 243
>4ARE-A nrPDB
Length = 695
Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust.
Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 10/91 (10%)
Query: 68 NAQVVLIPA--GVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVP 125
N Q IPA + + P FK+ + ++T++GK NA + VN+ VP
Sbjct: 118 NFQDKCIPAMIAIQKNPN------FKLGTAVQDEVITSLGKLIGNAS--ANAEVVNNCVP 169
Query: 126 IAVETLKKMGKFKPGNVMGVTNLDLVRAETF 156
+ + + + ++ P V G +L++ F
Sbjct: 170 VLKQFRENLNQYAPDYVKGTAVNELIKGIEF 200
>2Y6I-A nrPDB
Length = 785
Score = 30.4 bits (67), Expect = 1.2, Method: Compositional matrix adjust.
Identities = 22/91 (24%), Positives = 41/91 (45%), Gaps = 10/91 (10%)
Query: 68 NAQVVLIPA--GVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVP 125
N Q IPA + + P FK+ + ++T++GK NA + VN+ VP
Sbjct: 118 NFQDKCIPAMIAIQKNPN------FKLGTAVQDEVITSLGKLIGNAS--ANAEVVNNCVP 169
Query: 126 IAVETLKKMGKFKPGNVMGVTNLDLVRAETF 156
+ + + + ++ P V G +L++ F
Sbjct: 170 VLKQFRENLNQYAPDYVKGTAVNELIKGIEF 200
>6H1E-A nrPDB
Length = 208
Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 25/91 (27%), Positives = 40/91 (43%), Gaps = 6/91 (6%)
Query: 192 IIPIITD--KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVL 249
I P+ITD K L+ +L ++ + + F +V Q GS + A+AG + EV+
Sbjct: 91 IQPVITDLVKGLLPRLTEKVDLLV----FNPPYVVTPPQEVGSHGIEAAWAGGRNGREVM 146
Query: 250 RSFHNEKPETESLSAFVYLPGLKNGKKAQQL 280
F P+ S YL +K + L
Sbjct: 147 DRFFPLVPDLLSPRGLFYLVTIKENNPEEIL 177
>3QB0-A nrPDB
Length = 498
Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust.
Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 11/89 (12%)
Query: 218 FGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKA 277
+GGDE+ GS T ++ ++G+ F + +L S + + E +
Sbjct: 18 YGGDEVSAVVIDPGSYTTNIGYSGSDFPQSILPSVYGKYTADEGNKKIF----------S 67
Query: 278 QQLVGDNSIEYFSLPIVLRNGSVVSIDTS 306
+Q +G +Y PI+ NG V+ DT+
Sbjct: 68 EQSIGIPRKDYELKPII-ENGLVIDWDTA 95
>6APE-A nrPDB
Length = 298
Score = 30.0 bits (66), Expect = 1.5, Method: Compositional matrix adjust.
Identities = 33/107 (30%), Positives = 51/107 (47%), Gaps = 11/107 (10%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSS--CVGYDK-D 60
VAI+GAS +G+PLS+L+ L+ S + + KD+S N+ CVG K D
Sbjct: 173 VAIIGASNIIGKPLSMLM-LNAGAS------VSVCHILTKDISFYTQNADIVCVGVGKPD 225
Query: 61 SIENTLSNAQVVLIPAGVPR-KPGLTRDDLFKMNAGIVKSLVTAVGK 106
I+ ++ V++ G+ G D+ NA V +T V K
Sbjct: 226 LIKASMLKKGAVVVDIGINHLNDGRIVGDVDFTNAQKVAGFITPVPK 272
>5CEF-A nrPDB
Length = 375
Score = 29.3 bits (64), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 15/31 (48%), Positives = 19/31 (61%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL 32
+KV +LGA+G VGQ LL PY + AL
Sbjct: 9 IKVGVLGATGTVGQRFIELLAAHPYFALHAL 39
>2NVK-X nrPDB
Length = 488
Score = 28.9 bits (63), Expect = 3.8, Method: Compositional matrix adjust.
Identities = 18/53 (33%), Positives = 25/53 (47%), Gaps = 8/53 (15%)
Query: 61 SIENTLSNAQVVLIPAGVPRKP--------GLTRDDLFKMNAGIVKSLVTAVG 105
S E T++ V+ G PR P G+T DDLF ++ K+LV G
Sbjct: 144 SGERTITAQTFVIAVGGRPRYPDIPGAVEYGITSDDLFSLDREPGKTLVVGAG 196
>2BE7-D nrPDB
Length = 153
Score = 28.5 bits (62), Expect = 4.3, Method: Compositional matrix adjust.
Identities = 24/84 (28%), Positives = 37/84 (44%), Gaps = 11/84 (13%)
Query: 46 SHINTNSSCVGYDKDSIEN----------TLSNA-QVVLIPAGVPRKPGLTRDDLFKMNA 94
+H+ + C GY D I + +L++ Q V + +P K G +D + N
Sbjct: 4 NHMQVEAICNGYVIDHIPSGQGVKILKLFSLTDTKQRVTVGFNLPTKDGNAKDLIKVENT 63
Query: 95 GIVKSLVTAVGKFAPNARILVISN 118
I KS + APNA I +I N
Sbjct: 64 EITKSQANQLALLAPNATINIIEN 87
>4B9V-A nrPDB
Length = 619
Score = 27.7 bits (60), Expect = 7.5, Method: Compositional matrix adjust.
Identities = 27/100 (27%), Positives = 45/100 (45%), Gaps = 2/100 (2%)
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPET-ESLSAFVY-LPGLKNGKKAQQL 280
+V+ +Q S M FAG K + L E E ++ +Y L G + + +
Sbjct: 217 LVELEQPLSSILAEMEFAGVKVDTKRLEQMGEELAEQLRTVEQRIYELAGQEFNINSPKQ 276
Query: 281 VGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVN 320
+G E LP++ ++ + S VLEKL+P E + N
Sbjct: 277 LGVILFEKLQLPVLKKSKTGYSTSADVLEKLAPYHEIVEN 316
>3EH7-A nrPDB
Length = 434
Score = 27.7 bits (60), Expect = 7.6, Method: Compositional matrix adjust.
Identities = 29/139 (20%), Positives = 57/139 (41%), Gaps = 7/139 (5%)
Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAV-ETL 131
IP P + R D+ ++ IV+ + + S P + + E
Sbjct: 101 FIPVFFYEVPSMIRKDILHIDVAIVQLSMPDENGYCSFGVSCDYSKPAAESAHLVIGEIN 160
Query: 132 KKMGKFKPGNVMGVTNLDLVRAETFLVDYLM--LKNPKIGQEQDKTTMHRKVTVIGGHSG 189
++M N++ ++ LD + + DY + L PKIG+ ++ + + G +
Sbjct: 161 RQMPYVHGDNLIHISKLDYI----VMADYPIYSLAKPKIGEVEEAIGRNCAELIEDGATL 216
Query: 190 ETIIPIITDKSLVFQLDKQ 208
+ I I D +L+F DK+
Sbjct: 217 QLGIGAIPDAALLFLKDKK 235
>1RVY-A nrPDB
Length = 483
Score = 27.3 bits (59), Expect = 9.8, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 10/82 (12%)
Query: 194 PIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAG-SATL---SMAFAGAKFAEEVL 249
P +T + L+ + ++ HFIHR G + V+ + G ATL AG + + +
Sbjct: 405 PALTSRGLLEKDFQKVAHFIHR---GIELTVQIQDDTGPRATLKEFKEKLAGDEKHQRAV 461
Query: 250 RSFHNEKPETESLSAFVYLPGL 271
R+ + E ES +A LPGL
Sbjct: 462 RAL---RQEVESFAALFPLPGL 480
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
5ZI4-A nrPDB 395 e-110
1MLD-A nrPDB 278 2e-75
4E0B-A nrPDB 272 1e-73
4WLE-A nrPDB 272 2e-73
4L4S-H nrPDB 268 2e-72
5NQB-A nrPDB 268 3e-72
1IE3-A nrPDB 267 6e-72
4PLW-A nrPDB 267 7e-72
9LDB-A nrPDB 267 7e-72
1SMK-A nrPDB 266 1e-71
4AJN-A nrPDB 263 1e-70
6BAL-A nrPDB 261 4e-70
1LDM-A nrPDB 259 2e-69
4PLF-A nrPDB 255 2e-68
6CEP-A nrPDB 251 3e-67
4LN1-A nrPDB 250 6e-67
3PQF-A nrPDB 249 2e-66
5K0Z-A nrPDB 248 2e-66
2V65-A nrPDB 246 8e-66
1V6A-A nrPDB 246 1e-65
4ROS-A nrPDB 240 8e-64
3GVH-A nrPDB 239 2e-63
1GUZ-A nrPDB 236 1e-62
1LTH-T nrPDB 236 1e-62
3D0O-A nrPDB 234 4e-62
2HJR-A nrPDB 234 4e-62
1GV0-A nrPDB 234 4e-62
3TL2-A nrPDB 234 4e-62
3P7M-A nrPDB 234 5e-62
2LDB-A nrPDB 233 7e-62
1SOW-A nrPDB 231 2e-61
1A5Z-A nrPDB 231 3e-61
4M1Q-A nrPDB 230 1e-60
6J9S-A nrPDB 226 7e-60
4BGV-A nrPDB 226 1e-59
4Q3N-A nrPDB 224 4e-59
6H9S-A nrPDB 223 6e-59
6CT6-A nrPDB 223 7e-59
1UXJ-A nrPDB 221 4e-58
3NEP-X nrPDB 218 4e-57
1Y6J-A nrPDB 217 5e-57
3WSV-A nrPDB 214 5e-56
1EZ4-A nrPDB 211 3e-55
3ZZN-A nrPDB 208 2e-54
5MDH-A nrPDB 208 3e-54
4UUP-A nrPDB 201 4e-52
1PZF-A nrPDB 196 1e-50
1T24-A nrPDB 196 1e-50
5NFR-A nrPDB 193 9e-50
5HTO-A nrPDB 193 1e-49
1HYE-A nrPDB 193 1e-49
1OC4-A nrPDB 193 1e-49
5NUE-A nrPDB 192 1e-49
2V6B-A nrPDB 190 9e-49
4ND4-A nrPDB 189 1e-48
3FI9-A nrPDB 189 1e-48
4I1I-A nrPDB 187 7e-48
2D4A-B nrPDB 186 1e-47
4UUO-A nrPDB 185 2e-47
2X0J-A nrPDB 185 2e-47
4KDE-A nrPDB 183 1e-46
7MDH-A nrPDB 179 2e-45
1CIV-A nrPDB 177 6e-45
4BGU-A nrPDB 174 5e-44
4JCO-A nrPDB 170 6e-43
4UUM-A nrPDB 162 2e-40
3DL2-A nrPDB 153 1e-37
1B8U-A nrPDB 152 2e-37
6IHE-A nrPDB 146 1e-35
Sequences not found previously or not previously below threshold:
2LDX-A nrPDB 233 1e-61
3LDH-A nrPDB 195 2e-50
3D5T-A nrPDB 160 6e-40
4TVO-A nrPDB 153 1e-37
1HYH-A nrPDB 126 2e-29
3FEF-A nrPDB 38 0.005
3PLN-A nrPDB 37 0.008
4XRR-A nrPDB 36 0.032
1HE4-A nrPDB 35 0.039
3WMX-A nrPDB 34 0.081
5K0S-A nrPDB 34 0.092
3GRP-A nrPDB 34 0.092
3WYE-A nrPDB 33 0.18
1ORR-A nrPDB 33 0.21
4F3Y-A nrPDB 32 0.26
5C3M-A nrPDB 32 0.26
4NBV-A nrPDB 32 0.26
2EW8-A nrPDB 32 0.27
5ZF1-A nrPDB 32 0.51
1GEG-A nrPDB 31 0.63
2BE7-D nrPDB 31 0.66
1BXK-A nrPDB 31 0.73
5UYY-A nrPDB 31 0.76
1KEU-A nrPDB 31 0.77
5EES-A nrPDB 31 0.85
2GFQ-A nrPDB 31 0.89
2CVO-A nrPDB 31 0.96
4WOK-A nrPDB 31 1.2
3WTC-A nrPDB 31 1.2
2YV3-A nrPDB 31 1.2
2NNL-D nrPDB 31 1.2
4A7P-A nrPDB 30 1.4
3RFT-A nrPDB 30 1.5
2Q1W-A nrPDB 30 1.5
1LSS-A nrPDB 30 1.5
3G05-A nrPDB 30 1.6
3CP2-A nrPDB 30 1.9
5JW6-A nrPDB 30 2.0
5ITV-A nrPDB 30 2.0
4B4O-A nrPDB 30 2.1
1E3W-A nrPDB 29 2.3
5TEK-A nrPDB 29 2.3
2FV8-A nrPDB 29 2.4
3PWZ-A nrPDB 29 2.6
3RSH-A nrPDB 29 2.7
2C54-A nrPDB 29 2.8
6BI4-A nrPDB 29 3.2
1YS4-A nrPDB 29 3.2
5JCP-B nrPDB 29 3.2
3PZR-A nrPDB 29 3.2
5G4J-A nrPDB 29 3.3
3PRY-A nrPDB 29 3.4
3EMK-A nrPDB 29 3.5
2ZJ1-A nrPDB 29 3.6
5TEN-A nrPDB 29 3.8
4G65-A nrPDB 29 3.8
2R00-A nrPDB 29 3.9
2EP5-A nrPDB 29 3.9
3TZ6-A nrPDB 29 3.9
4MOW-A nrPDB 29 4.3
2BKA-A nrPDB 29 4.3
3W9B-A nrPDB 29 4.4
4YWJ-A nrPDB 29 4.6
2GAS-A nrPDB 29 4.6
6BMQ-A nrPDB 29 4.6
5C2K-A nrPDB 28 4.8
5ZHX-e nrPDB 28 4.9
3SXP-A nrPDB 28 4.9
2O3J-A nrPDB 28 5.0
5FWK-A nrPDB 28 5.0
2O23-A nrPDB 28 5.0
1QWG-A nrPDB 28 5.2
3I83-A nrPDB 28 5.2
2X86-A nrPDB 28 5.5
1EQ2-A nrPDB 28 5.5
3UW3-A nrPDB 28 5.6
6EL3-D nrPDB 28 5.6
2Z2C-A nrPDB 28 5.7
3PWS-A nrPDB 28 5.8
3N58-A nrPDB 28 5.9
1MV8-A nrPDB 28 6.3
4RFL-A nrPDB 28 6.7
3SQG-A nrPDB 28 7.0
3EH7-A nrPDB 28 7.6
4J6F-A nrPDB 27 8.6
4WOJ-A nrPDB 27 8.7
6QUZ-A nrPDB 27 9.0
3Q98-A nrPDB 27 9.0
>5ZI4-A nrPDB
Length = 345
Score = 395 bits (1015), Expect = e-110, Method: Composition-based stats.
Identities = 343/343 (100%), Positives = 343/343 (100%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60
MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD
Sbjct: 3 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 62
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV
Sbjct: 63 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 122
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK
Sbjct: 123 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 182
Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240
VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA
Sbjct: 183 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 242
Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300
GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV
Sbjct: 243 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 302
Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 343
VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL
Sbjct: 303 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 345
>1MLD-A nrPDB
Length = 314
Score = 278 bits (712), Expect = 2e-75, Method: Composition-based stats.
Identities = 144/337 (42%), Positives = 197/337 (58%), Gaps = 30/337 (8%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61
KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY +
Sbjct: 2 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQ 61
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+ + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P+A I +ISNPVN
Sbjct: 62 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPDAMICIISNPVN 121
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181
S +PI E KK G + P + GVT LD+VRA F+ + L ++ V
Sbjct: 122 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANAFVAELKGLDPARV-----------SV 170
Query: 182 TVIGGHSGETIIPIITDKSL-VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240
VIGGH+G+TIIP+I+ + V Q R+Q G E+VKAK GAGSATLSMA+A
Sbjct: 171 PVIGGHAGKTIIPLISQCTPKVDFPQDQLSTLTGRIQEAGTEVVKAKAGAGSATLSMAYA 230
Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300
GA+F ++ + + ++ E +FV + YFS P++L +
Sbjct: 231 GARFVFSLVDAMNGKEGVVE--CSFVKSQ-------------ETDCPYFSTPLLLGKKGI 275
Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+ K+SP EE+++ A+ EL+ +I+KG+ F+
Sbjct: 276 EKNLG--IGKISPFEEKMIAEAIPELKASIKKGEEFV 310
>4E0B-A nrPDB
Length = 313
Score = 272 bits (696), Expect = 1e-73, Method: Composition-based stats.
Identities = 132/338 (39%), Positives = 187/338 (55%), Gaps = 31/338 (9%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDI-RAAEGIGKDLSHINTNSSCVGYDK 59
+KVA++GA+GG+GQ L+LLLK P S+LALYDI G+ DLSHI T+ S GY
Sbjct: 4 MKVAVIGAAGGIGQALALLLKNRLPAGSDLALYDIAPVTPGVAADLSHIPTHVSIKGYAG 63
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ L A VVLI AGV RKPG+ R DLF +NAGIVKSL + PNA I +I+NP
Sbjct: 64 EDPTPALEGADVVLISAGVARKPGMDRADLFNVNAGIVKSLAERIAVVCPNACIGIITNP 123
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
VN+ VPIA E LKK G + + GVT LD++R+ETF+ + LK G+
Sbjct: 124 VNTTVPIAAEVLKKAGVYDKRKLFGVTTLDVIRSETFVAE---LKGQDPGE--------V 172
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
+V VIGGHSG TI+P+++ V D++ R+Q G E+V+AK G GSATLSM
Sbjct: 173 RVPVIGGHSGVTILPLLSQVEGVEFSDEEIAALTKRIQNAGTEVVEAKAGGGSATLSMGQ 232
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
A +F ++++ E+ + + Y+ G +F+ P+ L
Sbjct: 233 AACRFGLALVKALQGEE-----VIEYAYVEGNGEHAS-----------FFAQPVKLGKEG 276
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V I +LS E+ ++ ++ L +I+ G F+
Sbjct: 277 VEEI--LPYGELSDFEKAALDGMLETLNSDIQIGVDFV 312
>4WLE-A nrPDB
Length = 340
Score = 272 bits (695), Expect = 2e-73, Method: Composition-based stats.
Identities = 144/337 (42%), Positives = 197/337 (58%), Gaps = 30/337 (8%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61
KVA+LGASGG+GQPLSLLLK SP VS L LYDI G+ DLSHI T ++ GY +
Sbjct: 28 KVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQ 87
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+ + L VV+IPAGVPRKPG+TRDDLF NA IV +L A + P A I VI+NPVN
Sbjct: 88 LPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVN 147
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181
S +PI E KK G + P + GVT LD+VRA TF+ + L ++ V
Sbjct: 148 STIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARV-----------NV 196
Query: 182 TVIGGHSGETIIPIITDKSL-VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240
VIGGH+G+TIIP+I+ + V Q R+Q G E+VKAK GAGSATLSMA+A
Sbjct: 197 PVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYA 256
Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300
GA+F ++ + + ++ E +FV + YFS P++L +
Sbjct: 257 GARFVFSLVDAMNGKEGVVE--CSFVKSQ-------------ETECTYFSTPLLLGKKGI 301
Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+ K+S EE++++ A+ EL+ +I+KG+ F+
Sbjct: 302 EKNLG--IGKVSSFEEKMISDAIPELKASIKKGEDFV 336
>4L4S-H nrPDB
Length = 339
Score = 268 bits (686), Expect = 2e-72, Method: Composition-based stats.
Identities = 79/344 (22%), Positives = 144/344 (41%), Gaps = 41/344 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + + ELAL D+ +G DL H +
Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLRTPKIVSG 79
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
N +N+++V+I AG ++ G +R +L + N I K ++ V K++PN ++L++SNPV
Sbjct: 80 KDYNVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPNCKLLIVSNPV 139
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174
+ L +A K+ F V+G NLD R + + L + +G+ D
Sbjct: 140 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDS 195
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233
+ + G S +T+ P L DK+ +H+ V E++K K G
Sbjct: 196 SVPVWSGMNVAGVSLKTLHPD-----LGTDKDKEQWKEVHKQVVESAYEVIKLK---GYT 247
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+ ++ + A AE ++++ P + + + L G + S+P
Sbjct: 248 SWAIGLSVADLAESIMKNLRRVHPVSTMI---------------KGLYGIKDDVFLSVPC 292
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+L I V L+ EE + + L I+K F+
Sbjct: 293 ILGQNG---ISDLVKVTLTSEEEARLKKSADTLWG-IQKELQFL 332
>5NQB-A nrPDB
Length = 332
Score = 268 bits (684), Expect = 3e-72, Method: Composition-based stats.
Identities = 79/343 (23%), Positives = 144/343 (41%), Gaps = 41/343 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + + ELAL D+ +G DL H +
Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADELALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ +N+++V+I AG ++ G +R +L + N I K ++ V K++P+ ++LV+SNPV
Sbjct: 81 KDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPHCKLLVVSNPV 140
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLML-----KNPKIGQEQDK 174
+ L +A K+ F V+G NLD R + + L + +G+ D
Sbjct: 141 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHALSCHGWILGEHGDS 196
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233
+ + G S +T+ P L DK+ +H+ V E++K K G
Sbjct: 197 SVPVWSGMNVAGVSLKTLHP-----ELGTDADKEQWKQVHKQVVDSAYEVIKLK---GYT 248
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+ ++ + A AE ++++ P + L + L G + S+P
Sbjct: 249 SWAIGLSVADLAESIMKNLRRVHPISTML---------------KGLYGIKEDVFLSVPC 293
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
VL + + V L+ EE + + L I+K F
Sbjct: 294 VLGQNGISDV---VKVTLTSEEEAHLKKSADTLWG-IQKELQF 332
>1IE3-A nrPDB
Length = 312
Score = 267 bits (682), Expect = 6e-72, Method: Composition-based stats.
Identities = 130/338 (38%), Positives = 184/338 (54%), Gaps = 30/338 (8%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDI-RAAEGIGKDLSHINTNSSCVGYDK 59
+KVA+LGA+GG+GQ L+LLLK P SEL+LYDI G+ DLSHI T G+
Sbjct: 1 MKVAVLGAAGGIGQALALLLKTQLPSGSELSLYDIAPVTPGVAVDLSHIPTAVKIKGFSG 60
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ L A VVLI AGV RKPG+ R DLF +NAGIVK+LV V K P A I +I+NP
Sbjct: 61 EDATPALEGADVVLISAGVARKPGMDRSDLFNVNAGIVKNLVQQVAKTCPKACIGIITNP 120
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
VN+ V IA E LKK G + + GVT LD++ + TF+ + + ++
Sbjct: 121 VNTTVAIAAEVLKKAGVYDKNKLFGVTTLDIICSNTFVAELKGKQPGEV----------- 169
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
+V VIGGHSG TI+P+++ V +++ R+Q G E+V+AK G GSATLSM
Sbjct: 170 EVPVIGGHSGVTILPLLSQVPGVSFTEQEVADLTKRIQNAGTEVVEAKAGGGSATLSMGQ 229
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
A A+F ++R+ E+ E A+V G +FS P++L
Sbjct: 230 AAARFGLSLVRALQGEQGVVE--CAYVEGDGQY-------------ARFFSQPLLLGKNG 274
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V + + LS E+ + + L+K+I G+ F+
Sbjct: 275 VE--ERKSIGTLSAFEQNALEGMLDTLKKDIALGQEFV 310
>4PLW-A nrPDB
Length = 326
Score = 267 bits (681), Expect = 7e-72, Method: Composition-based stats.
Identities = 86/351 (24%), Positives = 160/351 (45%), Gaps = 55/351 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K++++GA G +G L+ L+ + ++ L+DI GK L I+ +S +G +
Sbjct: 6 KISLIGA-GNIGGTLAHLIA-QKELGDVVLFDIVEGMPQGKALD-ISHSSPIMGSNVKIT 62
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ + + VV+I AG+PRKPG++RDDL +NA I+K + + K+ PNA ++V++N
Sbjct: 63 GTNNYEDIKGSDVVIITAGIPRKPGMSRDDLLSVNAKIMKDVAENIKKYCPNAFVIVVTN 122
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++ +V + L K V G+ LD R FL + L + +
Sbjct: 123 PLDVMVYV----LHKYSGLPHNKVCGMAGVLDSSRFRYFLAEKLNVSPNDV--------- 169
Query: 178 HRKVTVIGGHSGETIIPIITDKSL-----------VFQLDKQYEHFIHRVQFGGDEIVKA 226
+ VIGGH G+T++P+ ++ + ++ + + R + G EIV
Sbjct: 170 --QAMVIGGH-GDTMVPLTRYCTVGGIPLTEFIKQGWITQEEIDEIVERTRNAGGEIVNL 226
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286
+ GSA + A + + AE L+ P YL G K
Sbjct: 227 LK-TGSAYFAPAASAIEMAESYLKDKKRILPC------SAYLEGQYGVKDL--------- 270
Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+ +P+++ V I + +L+ E+++ + +V+ +R+ +E K
Sbjct: 271 -FVGVPVIIGKNGVEKI---IELELTEEEQEMFDKSVESVRELVETVKKLN 317
>9LDB-A nrPDB
Length = 332
Score = 267 bits (681), Expect = 7e-72, Method: Composition-based stats.
Identities = 77/343 (22%), Positives = 145/343 (42%), Gaps = 41/343 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + + E+AL D+ +G DL H +
Sbjct: 22 KITVVGV-GAVGMACAISILMKELADEIALVDVMEDKLKGEMMDLQHGSLFLRTPKIVSG 80
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
N +N+++V+I AG ++ G +R +L + N I K ++ + K++PN ++LV+SNPV
Sbjct: 81 KDYNVTANSRLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCKLLVVSNPV 140
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174
+ L +A K+ F V+G NLD R + + L + +G+ D
Sbjct: 141 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWILGEHGDS 196
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233
+ + G S + + P L DK++ +H+ V E++K K G
Sbjct: 197 SVPVWSGVNVAGVSLKNLHP-----ELGTDADKEHWKAVHKEVVDSAYEVIKLK---GYT 248
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+ ++ + A AE ++++ P + + + L G + S+P
Sbjct: 249 SWAIGLSVADLAESIMKNLRRVHPISTMI---------------KGLYGIKENVFLSVPC 293
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+L + + V L+P EE + + L I+K F
Sbjct: 294 ILGQNGISDV---VKVTLTPEEEAHLKKSADTLWG-IQKELQF 332
>1SMK-A nrPDB
Length = 326
Score = 266 bits (679), Expect = 1e-71, Method: Composition-based stats.
Identities = 139/337 (41%), Positives = 197/337 (58%), Gaps = 30/337 (8%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-DKDS 61
KVAILGA+GG+GQPL++L+K++P VS L LYD+ A G+ D+SH++T + G+ +
Sbjct: 10 KVAILGAAGGIGQPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQ 69
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+E L+ ++++PAGVPRKPG+TRDDLFK+NAGIVK+L + K P A + +ISNPVN
Sbjct: 70 LEAALTGMDLIIVPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPRAIVNLISNPVN 129
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKV 181
S VPIA E KK G + P ++GVT LD+VRA TF+ + L L + V
Sbjct: 130 STVPIAAEVFKKAGTYDPKRLLGVTMLDVVRANTFVAEVLGLDPRDV-----------DV 178
Query: 182 TVIGGHSGETIIPIITD-KSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFA 240
V+GGH+G TI+P+++ K ++ + R+Q GG E+V+AK GAGSATLSMA+A
Sbjct: 179 PVVGGHAGVTILPLLSQVKPPSSFTQEEISYLTDRIQNGGTEVVEAKAGAGSATLSMAYA 238
Query: 241 GAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSV 300
KFA+ LR + E AFV + +F+ + L +
Sbjct: 239 AVKFADACLRGLRGDAGVIE--CAFVSSQ-------------VTELPFFASKVRLGRNGI 283
Query: 301 VSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+ L L+ E + A KEL +IEKG SFI
Sbjct: 284 EEV--YSLGPLNEYERIGLEKAKKELAGSIEKGVSFI 318
>4AJN-A nrPDB
Length = 331
Score = 263 bits (671), Expect = 1e-70, Method: Composition-based stats.
Identities = 76/343 (22%), Positives = 144/343 (41%), Gaps = 41/343 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + + ELAL D+ +G DL H +
Sbjct: 21 KITVVGV-GAVGMACAISILMKDLADELALVDVIEDKLKGEMMDLQHGSLFLKTPKIVSS 79
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ +N+++V+I AG ++ G +R +L + N I K ++ V K++P ++L++SNPV
Sbjct: 80 KDYSVTANSKLVIITAGARQQEGESRLNLVQRNVNIFKFIIPNVVKYSPQCKLLIVSNPV 139
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174
+ L +A K+ F V+G NLD R + + L + +G+ D
Sbjct: 140 DILTYVA----WKISGFPKNRVIGSGCNLDSARFRYLMGERLGVHPLSCHGWVLGEHGDS 195
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233
+ + G S +++ P L DK+ +H+ V E++K K G
Sbjct: 196 SVPVWSGVNVAGVSLKSLNP-----QLGTDADKEQWKDVHKQVVDSAYEVIKLK---GYT 247
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+ ++ + A AE ++++ P + + + L G + S+P
Sbjct: 248 SWAIGLSVADLAESIMKNLRRVHPISTMI---------------KGLYGIKEDVFLSVPC 292
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+L + + V L+P EE + + L I+K F
Sbjct: 293 ILGQNGISDV---VKVTLTPDEEARLKKSADTLWG-IQKELQF 331
>6BAL-A nrPDB
Length = 335
Score = 261 bits (666), Expect = 4e-70, Method: Composition-based stats.
Identities = 132/338 (39%), Positives = 187/338 (55%), Gaps = 31/338 (9%)
Query: 2 VKVAILGASGGVGQPLSLLLKLS-PYVSELALYDI-RAAEGIGKDLSHINTNSSCVGYDK 59
+KVA+LGA+GG+GQ L+LLLKL P ++L+LYDI G+ D+SHI T + G+
Sbjct: 25 MKVAVLGAAGGIGQALALLLKLQLPAGTDLSLYDIAPVTPGVAVDVSHIPTAVNVKGFSG 84
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ L A VVLI AGV RKPG+ R DLF +NAGIV+ L+ V P A + +I+NP
Sbjct: 85 EDPTPALEGADVVLISAGVARKPGMDRSDLFNINAGIVRGLIEKVAVTCPKACVGIITNP 144
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
VN+ V IA E LKK G + + GVT LD++R+ETF+ + L +
Sbjct: 145 VNTTVAIAAEVLKKAGVYDKRKLFGVTTLDVLRSETFVAELKGLNVSRT----------- 193
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
V VIGGHSG TI+P+++ + + E R+Q G E++ AK G GSATLSMA
Sbjct: 194 SVPVIGGHSGVTILPLLSQVQYAKWNEDEIEPLTKRIQNAGTEVLNAKAGGGSATLSMAQ 253
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
A A+FA +++ E++ Y+ G +GK A+ +FS P+ L
Sbjct: 254 AAARFARSLVKGL-----SGETVVECTYVEG--DGKYAR---------FFSQPVRLGKEG 297
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V I + LS E+Q + + LR +IE G+ FI
Sbjct: 298 VEEI--LPIGPLSNFEQQALENMLPTLRADIELGEKFI 333
>1LDM-A nrPDB
Length = 329
Score = 259 bits (661), Expect = 2e-69, Method: Composition-based stats.
Identities = 73/342 (21%), Positives = 137/342 (40%), Gaps = 42/342 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + + E+AL D+ +G DL H +
Sbjct: 22 KITVVGV-GAVGMACAISILMKDLADEVALVDVMEDKLKGEMMDLQHGSLFLHTAKIVSG 80
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ + +++V+I AG ++ G +R +L + N I K ++ + K +P+ ILV+SNPV
Sbjct: 81 KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDCIILVVSNPV 140
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLML-----KNPKIGQEQDK 174
+ L +A K+ ++G NLD R + + L + IG+ D
Sbjct: 141 DVLTYVA----WKLSGLPMHRIIGSGCNLDSARFRYLMGERLGVHSCSCHGWVIGEHGDS 196
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234
+ + P+ + + ++ V E++K K G +
Sbjct: 197 VPSVWSGMNVASIK---LHPL----DGTNKDKQDWKKLHKDVVDSAYEVIKLK---GYTS 246
Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294
++ + A AE ++++ P + + F G + SLP V
Sbjct: 247 WAIGLSVADLAETIMKNLCRVHPVSTMVKDF---------------YGIKDNVFLSLPCV 291
Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
L + + +I V KL P EEQ + + L +I+K F
Sbjct: 292 LNDHGISNI---VKMKLKPNEEQQLQKSATTLW-DIQKDLKF 329
>4PLF-A nrPDB
Length = 334
Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats.
Identities = 84/360 (23%), Positives = 154/360 (42%), Gaps = 64/360 (17%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSH----INTNSSCVG 56
K++++G SG +G ++ L + ++ L+D+ +G DLSH +TN G
Sbjct: 10 KISLIG-SGMIGGTMAYLCA-QKELGDVVLFDVVKNMPQGKALDLSHSSSIADTNVKVTG 67
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNA 111
+ + + VV+I AG+ + PG +RDDL NA I++ + + K+ PNA
Sbjct: 68 TNS---YEDIKGSDVVIITAGLTKAPGKSDKEWSRDDLLPFNAKIMREVGENIKKYCPNA 124
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQ 170
++VI+NP++ +V + L + V G+ LD R F+ + L + +
Sbjct: 125 FVIVITNPLDVMVKV----LHEHSGLPKNKVCGMAGVLDSSRFRHFIAEKLNVSPRDV-- 178
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVF-----------QLDKQYEHFIHRVQFG 219
+ VIG H G+ ++P+ ++ ++ + + R +
Sbjct: 179 ---------QAMVIGAH-GDKMVPLTRYVTVNGIPLQEFIKKGRITQEEIDEIVERTKNA 228
Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQ 279
G EIV G GSA + A + + AE L+ L YL G K
Sbjct: 229 GGEIVNLL-GQGSAYFAPAASAIEMAEAYLKDKKRV------LVCSCYLEGQYGHKDM-- 279
Query: 280 LVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILD 339
+ +P V+ V + +L+P E++L + +V+E+RK + K+ L+
Sbjct: 280 --------FVGVPAVIGGNGVEKVIEL---ELTPEEKELFDKSVEEVRKLQKAIKALGLE 328
>6CEP-A nrPDB
Length = 334
Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats.
Identities = 71/343 (20%), Positives = 138/343 (40%), Gaps = 40/343 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + ELAL D+ +G DL H + D
Sbjct: 23 KITVVGV-GQVGMACAISILGKSLTDELALVDVLEDKLKGEMMDLQHGSLFLQTPKIVAD 81
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ +N+++V++ AGV ++ G +R +L + N + K ++ + K++P+ I+V+SNPV
Sbjct: 82 KDYSVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDCIIIVVSNPV 141
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174
+ L + K+ V+G NLD R + + L + +G+ D
Sbjct: 142 DILTYVT----WKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGVHPSSCHGWILGEHGDS 197
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233
+ + G S + + P + D + +H+ V E++K K G
Sbjct: 198 SVAVWSGVNVAGVSLQELNP-----EMGTDNDSENWKEVHKMVVESAYEVIKLK---GYT 249
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
++ + A E +L++ P + + Q + G + + SLP
Sbjct: 250 NWAIGLSVADLIESMLKNLSRIHPVSTMV---------------QGMYGIENEVFLSLPC 294
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
VL + S+ + +KL E + + L + K
Sbjct: 295 VLNARGLTSV---INQKLKDDEVAQLKNSADTLWGIQKDLKDL 334
>4LN1-A nrPDB
Length = 336
Score = 250 bits (638), Expect = 6e-67, Method: Composition-based stats.
Identities = 80/343 (23%), Positives = 131/343 (38%), Gaps = 54/343 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60
+V ++G +G VG + + E L D+ AEG DLSH +
Sbjct: 29 RVVLVG-TGAVGCSYAYCMINQAVAEEFVLVDVNEAKAEGEAMDLSHAVPFAPAPTRVWK 87
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+A +V+I AG+P+KPG TR DL + NA I K +V ++ + L+ +NPV
Sbjct: 88 GSYEDCKDADLVVITAGLPQKPGETRLDLVEKNAKIFKQIVRSIMDSGFDGIFLIATNPV 147
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
+ L + K V+G T LD R L +Y + I
Sbjct: 148 DILTYVT----WKESGLPKERVIGSGTTLDSARFRYMLGEYFDIGPHNI----------- 192
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQ------------LDKQYEHFIHRVQFGGDEIVKAK 227
+IG H G+T +P+ + S+ Q + + V+ I++ K
Sbjct: 193 HAYIIGEH-GDTELPVWSHVSVGIQKLQTLLEKDNTYNQEDLDKIFINVRDAAYHIIERK 251
Query: 228 QGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIE 287
G+ + + + + +L E L+ YL G K
Sbjct: 252 ---GATYYGIGMSLLRVTKAILND------ENSVLTVSAYLEGQYGQKD----------V 292
Query: 288 YFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNI 330
Y +P VL G V I +LS EE + +V+ L++ +
Sbjct: 293 YIGVPAVLNRGGVREILEV---ELSEDEELKFDHSVQVLKETM 332
>3PQF-A nrPDB
Length = 326
Score = 249 bits (635), Expect = 2e-66, Method: Composition-based stats.
Identities = 73/337 (21%), Positives = 122/337 (36%), Gaps = 40/337 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKD 60
KVA++GA G VG + L EL + D+ A G DL+H +
Sbjct: 7 KVALIGA-GFVGSSYAFALINQGITDELVVIDVNKEKAMGDVMDLNHGKAFAPQPVKTSY 65
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+A +V I AG +KPG TR +L + N I K +V+ V + LV +NPV
Sbjct: 66 GTYEDCKDADIVCICAGANQKPGETRLELVEKNLKIFKGIVSEVMASGFDGIFLVATNPV 125
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNP-----KIGQEQDK 174
+ L K V+G T LD R L +Y IG+ D
Sbjct: 126 DILTY----ATWKFSGLPKERVIGSGTTLDSARFRFMLSEYFGAAPQNVCAHIIGEHGDT 181
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234
+GG ++ ++ + + V+ I++ K G+
Sbjct: 182 ELPVWSHANVGGVPVSELVE-----KNDAYKQEELDQIVDDVKNAAYHIIEKK---GATY 233
Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294
+A + A+ + +L + E L+ YL G Y +P V
Sbjct: 234 YGVAMSLARITKAILHN------ENSILTVSTYLDGQYGA----------DDVYIGVPAV 277
Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331
+ G + I L+ +E++ + L+ ++
Sbjct: 278 VNRGGIAGITEL---NLNEKEKEQFLHSAGVLKNILK 311
>5K0Z-A nrPDB
Length = 331
Score = 248 bits (634), Expect = 2e-66, Method: Composition-based stats.
Identities = 70/342 (20%), Positives = 137/342 (40%), Gaps = 40/342 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G G VG ++ + ELAL D+ +G DL H + D
Sbjct: 21 KITVVGV-GQVGMACAISILGKGLCDELALVDVLEDKLKGEMMDLQHGSLFLQTHKIVAD 79
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+N+++V++ AGV ++ G +R +L + N + K ++ + K++PN ILV+SNPV
Sbjct: 80 KDYAVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPNCTILVVSNPV 139
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174
+ L + K+ V+G NLD R + + L + +G+ D
Sbjct: 140 DILTYVT----WKLSGLPKHRVIGSGCNLDTARFRYLMAERLGIHPTSCHGWILGEHGDS 195
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSA 233
+ + G S + + P + D + +H+ V E+++ K G
Sbjct: 196 SVAVWSGVNVAGVSLQELNPAM-----GTDKDSENWKEVHKQVVESAYEVIRLK---GYT 247
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
++ + A+ E +L++ + + + + G + + SLP
Sbjct: 248 NWAIGLSVAELCETMLKNLYRVHSVSTLV---------------KGTYGIENDVFLSLPC 292
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335
VL + S+ + +KL E + + L + K
Sbjct: 293 VLSASGLTSV---INQKLKDDEVAQLKKSADTLWSIQKDLKD 331
>2V65-A nrPDB
Length = 331
Score = 246 bits (629), Expect = 8e-66, Method: Composition-based stats.
Identities = 71/322 (22%), Positives = 134/322 (41%), Gaps = 40/322 (12%)
Query: 16 PLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVL 73
++ + L ELA+ D+ +G DL H + D + +N++VV+
Sbjct: 34 ASAISILLKDLCDELAMVDVMEDKLKGEVMDLQHGSLFLKTKIV-GDKDYSVTANSKVVV 92
Query: 74 IPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKK 133
+ AG ++ G +R +L + N I K ++ + K++PN ++V+SNPV+ L +A K
Sbjct: 93 VTAGARQQEGESRLNLVQRNVNIFKFIIPNIVKYSPNCILMVVSNPVDILTYVA----WK 148
Query: 134 MGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDKTTMHRKVTVIGGH 187
+ F V+G TNLD R + + L L +G+ D + + G
Sbjct: 149 LSGFPRHRVIGSGTNLDSARFRHLIGEKLHLHPSSCHAWIVGEHGDSSVPVWSGVNVAGV 208
Query: 188 SGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMAFAGAKFAE 246
S + + P + + D + IH+ V G E++K K G + ++ + A E
Sbjct: 209 SLQGLNP-----QMGTEGDGENWKAIHKEVVDGAYEVIKLK---GYTSWAIGMSVADLVE 260
Query: 247 EVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTS 306
++++ H P + + Q + G + S+P VL N + +
Sbjct: 261 SIIKNMHKVHPVSTLV---------------QGMHGVKDEVFLSVPCVLGNSGLTDVIHM 305
Query: 307 VLEKLSPREEQLVNTAVKELRK 328
L EE+ + + + L
Sbjct: 306 T---LKAEEEKQLQKSAETLWG 324
>1V6A-A nrPDB
Length = 332
Score = 246 bits (627), Expect = 1e-65, Method: Composition-based stats.
Identities = 71/324 (21%), Positives = 134/324 (41%), Gaps = 39/324 (12%)
Query: 19 LLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLIPA 76
+ + L ELAL D+ +G DL H + D + +N++VV++ A
Sbjct: 37 ISILLKDLTDELALVDVMEDKLKGEAMDLQHGSLFLKTHKIVADKDYSVTANSKVVVVTA 96
Query: 77 GVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGK 136
G ++ G +R +L + N I K ++ + K++PN +LV+SNPV+ L +A K+
Sbjct: 97 GARQQEGESRLNLVQRNVNIFKFIIPNIIKYSPNCILLVVSNPVDILTYVA----WKLSG 152
Query: 137 FKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDKTTMHRKVTVIGGHSGE 190
V+G TNLD R + + L + IG+ D + + G +
Sbjct: 153 LPRNRVIGSGTNLDSARFRHLMGEKLGIHPSNCHGWVIGEHGDSSVPVWSGVNVAGVFLQ 212
Query: 191 TIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVL 249
+ P + DK+ +H+ V E++K K G + ++ + A + +L
Sbjct: 213 GLNPDM-----GTDKDKEDWKSVHKMVVDSAYEVIKLK---GYTSWAIGMSAADLCQSIL 264
Query: 250 RSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLE 309
++ P + + + + G N + S+P +L N + + L+
Sbjct: 265 KNLRKCHPVSTLV---------------KGMHGVNEEVFLSVPCILGNSGLTDVVHMTLK 309
Query: 310 KLSPREEQLVNTAVKELRKNIEKG 333
S E+QLV + + L +
Sbjct: 310 --SDEEKQLV-KSAETLWGVQKDL 330
>4ROS-A nrPDB
Length = 320
Score = 240 bits (611), Expect = 8e-64, Method: Composition-based stats.
Identities = 84/345 (24%), Positives = 150/345 (43%), Gaps = 43/345 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K+A++GA G +G L+ L L + ++ L+DI GK L I ++ G+D
Sbjct: 5 KIALIGA-GQIGGTLAHLAGLKE-LGDVVLFDIVDGVPQGKALD-IAESAPVDGFDAKYS 61
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
S + ++ A VV++ AGVPRKPG++RDDL +N +++++ + + AP+A ++ I+N
Sbjct: 62 GASDYSAIAGADVVIVTAGVPRKPGMSRDDLIGINLKVMEAVGAGIKEHAPDAFVICITN 121
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQEQ 172
P++++V L+K V+G+ LD R FL + + + G
Sbjct: 122 PLDAMV----WALQKFSGLPTNKVVGMAGVLDSARFRHFLAEEFGVSVEDVTAFVLGGHG 177
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232
D + + + G +P+ L + ++ + + R + GG EIV + GS
Sbjct: 178 DDMVPLTRYSTVAG------VPLTDLVKLGWTTQEKLDAMVERTRKGGGEIVNLLK-TGS 230
Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292
A + A + AE LR P L + GL Y +P
Sbjct: 231 AFYAPAASAIAMAESYLRDKKRVLPCAAYLDGQYGIDGL----------------YVGVP 274
Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+V+ V + + E+ + +V ++ IE KS
Sbjct: 275 VVIGENGVERVLEVT---FNDDEKAMFEKSVNSVKGLIEACKSVN 316
>3GVH-A nrPDB
Length = 324
Score = 239 bits (609), Expect = 2e-63, Method: Composition-based stats.
Identities = 85/339 (25%), Positives = 142/339 (41%), Gaps = 43/339 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K+A++G SG +G L+ L L + ++ L+DI GK L I +S G+D
Sbjct: 9 KIALIG-SGMIGGTLAHLAGLKE-LGDVVLFDIAEGTPQGKGLD-IAESSPVDGFDAKFT 65
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ + A VV++ AGVPRKPG++RDDL +N +++ + + K+AP A ++ I+N
Sbjct: 66 GANDYAAIEGADVVIVTAGVPRKPGMSRDDLLGINLKVMEQVGAGIKKYAPEAFVICITN 125
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQEQ 172
P++++V L+K V+G+ LD R FL + + + G
Sbjct: 126 PLDAMV----WALQKFSGLPAHKVVGMAGVLDSARFRYFLSEEFNVSVEDVTVFVLGGHG 181
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232
D + + + G IP+ + + + + I R + GG EIV + GS
Sbjct: 182 DSMVPLARYSTVAG------IPLPDLVKMGWTSQDKLDKIIQRTRDGGAEIVGLLK-TGS 234
Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292
A + A + + AE L+ P LS G K Y +P
Sbjct: 235 AFYAPAASAIQMAESYLKDKKRVLPVAAQLS------GQYGVKDM----------YVGVP 278
Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331
V+ V I L E+ + +V + E
Sbjct: 279 TVIGANGVERIIEI---DLDKDEKAQFDKSVASVAGLCE 314
>1GUZ-A nrPDB
Length = 310
Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats.
Identities = 82/347 (23%), Positives = 144/347 (41%), Gaps = 49/347 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD--- 58
+K+ ++GA G VG + L EL L D+ GK L + + +D
Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDVVEGIPQGKALD-MYESGPVGLFDTKV 58
Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
+ +N+ +V+I AG+PRKPG+TR+DL NAGIVK + + K + N I+V+S
Sbjct: 59 TGSNDYADTANSDIVIITAGLPRKPGMTREDLLMKNAGIVKEVTDNIMKHSKNPIIIVVS 118
Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
NP++ + +A V+G+ LD R +F+ L + I
Sbjct: 119 NPLDIMTHVA----WVRSGLPKERVIGMAGVLDAARFRSFIAMELGVSMQDI-------- 166
Query: 177 MHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKAKQGA 230
V+GGH G+ ++P++ ++ + + + R + GG EIV+ +
Sbjct: 167 ---NACVLGGH-GDAMVPVVKYTTVAGIPISDLLPAETIDKLVERTRNGGAEIVEHLK-Q 221
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290
GSA + A + + E ++ P V L G +
Sbjct: 222 GSAFYAPASSVVEMVESIVLDRKRVLPCA------VGLEGQYG----------IDKTFVG 265
Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+P+ L V I L++ + L+ + K + +N + +S I
Sbjct: 266 VPVKLGRNGVEQIYEINLDQA---DLDLLQKSAKIVDENCKMLESTI 309
>1LTH-T nrPDB
Length = 319
Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats.
Identities = 74/336 (22%), Positives = 129/336 (38%), Gaps = 38/336 (11%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDK 59
K+A++GA G VG L+ E+ L DI E D+ H ++ V D
Sbjct: 8 TKLAVIGA-GAVGSTLAFAAAQRGIAREIVLEDIAKERVEAEVLDMQHGSSFYPTVSIDG 66
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+A +V+I AG +KPG +R +L I+K+++ + K APNA ++I+NP
Sbjct: 67 SDDPEICRDADMVVITAGPRQKPGQSRLELVGATVNILKAIMPNLVKVAPNAIYMLITNP 126
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLM-----LKNPKIGQEQD 173
V+ +A +K+ + G TNLD R + + G+ D
Sbjct: 127 VDIATHVA----QKLTGLPENQIFGSGTNLDSARLRFLIAQQTGVNVKNVHAYIAGEHGD 182
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233
+ IGG P+ L DK+ E V+ +I+ K G+
Sbjct: 183 SEVPLWESATIGGVPMSDWTPLPGHDPL--DADKR-EEIHQEVKNAAYKIINGK---GAT 236
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
++ +G E VL + P + L F + + S+P
Sbjct: 237 NYAIGMSGVDIIEAVLHDTNRILPVSSMLKDFHGISDIC----------------MSVPT 280
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKN 329
+L V + + +S +E + + + L++
Sbjct: 281 LLNRQGVNNTINT---PVSDKELAALKRSAETLKET 313
>3D0O-A nrPDB
Length = 317
Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats.
Identities = 76/342 (22%), Positives = 123/342 (35%), Gaps = 41/342 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVGYDKD 60
KV ++G +G VG + L V EL + D+ G DL H S K
Sbjct: 8 KVVLIG-NGAVGSSYAFSLVNQSIVDELVIIDLDTEKVRGDVMDLKHATPYSPTTVRVKA 66
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ +A +V+I AG +KPG TR DL N I KS+V V + LV +NPV
Sbjct: 67 GEYSDCHDADLVVICAGAAQKPGETRLDLVSKNLKIFKSIVGEVMASKFDGIFLVATNPV 126
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKN-----PKIGQEQDK 174
+ L K V+G T LD R L + + IG+ D
Sbjct: 127 DILAY----ATWKFSGLPKERVIGSGTILDSARFRLLLSEAFDVAPRSVDAQIIGEHGDT 182
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234
I G +T++ + Q E + + +I++AK G+
Sbjct: 183 ELPVWSHANIAGQPLKTLLEQ------RPEGKAQIEQIFVQTRDAAYDIIQAK---GATY 233
Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294
+A A+ E + R+ E L+ L G + Y +P V
Sbjct: 234 YGVAMGLARITEAIFRN------EDAVLTVSALLEGEY----------EEEDVYIGVPAV 277
Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+ + ++ L+ E+ + K L+ + + +
Sbjct: 278 INRNGIRNVVEI---PLNDEEQSKFAHSAKTLKDIMAEAEEL 316
>2HJR-A nrPDB
Length = 328
Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats.
Identities = 95/352 (26%), Positives = 158/352 (44%), Gaps = 55/352 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINT--NSSCVGYD 58
K++I+GA G +G ++LLL + ++ ++DI +G DL+H S +
Sbjct: 16 KISIIGA-GQIGSTIALLLGQKD-LGDVYMFDIIEGVPQGKALDLNHCMALIGSPAKIFG 73
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+++ E L N+ VV+I AGVPRKP +TR DL +NA IV S+ VGK+ PNA ++ I+N
Sbjct: 74 ENNYE-YLQNSDVVIITAGVPRKPNMTRSDLLTVNAKIVGSVAENVGKYCPNAFVICITN 132
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++++V K+ V G++ LD R L L +K +
Sbjct: 133 PLDAMVY----YFKEKSGIPANKVCGMSGVLDSARFRCNLSRALGVKPSDV--------- 179
Query: 178 HRKVTVIGGHSGETIIPIITDKSL-----------VFQLDKQYEHFIHRVQFGGDEIVKA 226
V+GGH G+ +IP+ + ++ Q I + FGG EIV+
Sbjct: 180 --SAIVVGGH-GDEMIPLTSSVTIGGILLSDFVEQGKITHSQINEIIKKTAFGGGEIVEL 236
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286
+ GSA + A + A+ L+ L YL G N
Sbjct: 237 LK-TGSAFYAPAASAVAMAQAYLKD------SKSVLVCSTYLTGQYNVNNL--------- 280
Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338
+ +P+V+ I+ V+ LS E+ L + +V+ ++ ++ KS L
Sbjct: 281 -FVGVPVVIGKNG---IEDVVIVNLSDDEKSLFSKSVESIQNLVQDLKSLNL 328
>1GV0-A nrPDB
Length = 310
Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats.
Identities = 82/352 (23%), Positives = 147/352 (41%), Gaps = 54/352 (15%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD--- 58
+K+ ++GA G VG + L EL L D+ GK L + + +D
Sbjct: 1 MKITVIGA-GNVGATTAFRLAEKQLARELVLLDVVEGIPQGKALD-MYESGPVGLFDTKV 58
Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
+ +N+ +V+I AG+PRKPG+TR+DL MNAGIV+ + + + + N I+V+S
Sbjct: 59 TGSNDYADTANSDIVVITAGLPRKPGMTREDLLSMNAGIVREVTGRIMEHSKNPIIVVVS 118
Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
NP++ + +A + V+G+ LD R +F+ L + +
Sbjct: 119 NPLDIMTHVA----WQKSGLPKERVIGMAGVLDSARFRSFIAMELGVSMQDVT------- 167
Query: 177 MHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKAKQGA 230
V+GGH G+ ++P++ ++ ++ + R + GG EIV +
Sbjct: 168 ----ACVLGGH-GDAMVPVVKYTTVAGIPVADLISAERIAELVERTRTGGAEIVNHLK-Q 221
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290
GSA S A + + E ++ SL + G +
Sbjct: 222 GSAFYSPATSVVEMVESIVLDRKRVLTCAVSLDGQYGIDG----------------TFVG 265
Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSK 342
+P+ L V I KL + L+ + K + +N + +LD+S+
Sbjct: 266 VPVKLGKNGVEHIYEI---KLDQSDLDLLQKSAKIVDENCK-----MLDASQ 309
>3TL2-A nrPDB
Length = 315
Score = 234 bits (596), Expect = 4e-62, Method: Composition-based stats.
Identities = 93/344 (27%), Positives = 149/344 (43%), Gaps = 50/344 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG--IGKDLSHINTNSSCVGYDKD 60
KV+++GA G G + LL ++ L DI E GK L + S G+D +
Sbjct: 10 KVSVIGA-GFTGATTAFLLAQKELA-DVVLVDIPQLENPTKGKALDML-EASPVQGFDAN 66
Query: 61 ----SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
S +++ VV+I AG+ RKPG++RDDL N+ I+KS+ + K +PNA I+V+
Sbjct: 67 IIGTSDYADTADSDVVVITAGIARKPGMSRDDLVATNSKIMKSITRDIAKHSPNAIIVVL 126
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKI-----GQ 170
+NPV+++ K F V+G + LD R TF+ L L I G
Sbjct: 127 TNPVDAMTYSVF----KEAGFPKERVIGQSGVLDTARFRTFIAQELNLSVKDITGFVLGG 182
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGA 230
D + + GG ET+IP ++ E + R + GG EIV G
Sbjct: 183 HGDDMVPLVRYSYAGGIPLETLIP-----------KERLEAIVERTRKGGGEIVGLL-GN 230
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290
GSA + A + + E +L+ P A YL G S Y
Sbjct: 231 GSAYYAPAASLVEMTEAILKDQRRVLP------AIAYLEGEYG----------YSDLYLG 274
Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK 334
+P++L + I +L E++ ++ +V+ +R ++
Sbjct: 275 VPVILGGNGIEKIIEL---ELLADEKEALDRSVESVRNVMKVLV 315
>3P7M-A nrPDB
Length = 321
Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats.
Identities = 82/351 (23%), Positives = 154/351 (43%), Gaps = 54/351 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K+ ++GA G +G L+ L + + ++ L+DI GK L + T G D
Sbjct: 7 KITLVGA-GNIGGTLAHLALIKQ-LGDVVLFDIAQGMPNGKALDLLQT-CPIEGVDFKVR 63
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ L N+ VV++ AGVPRKPG++RDDL +N +++++ + PNA ++ I+N
Sbjct: 64 GTNDYKDLENSDVVIVTAGVPRKPGMSRDDLLGINIKVMQTVGEGIKHNCPNAFVICITN 123
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++ +V L+K ++G+ LD R TFL D L + ++
Sbjct: 124 PLDIMV----NMLQKFSGVPDNKIVGMAGVLDSARFRTFLADELNVSVQQV--------- 170
Query: 178 HRKVTVIGGHSGETIIPIITDKSLV-----------FQLDKQYEHFIHRVQFGGDEIVKA 226
+ V+GGH G+T++P+ ++ ++ + + R + GG EIV
Sbjct: 171 --QAYVMGGH-GDTMVPLTKMSNVAGVSLEQLVKEGKLKQERLDAIVSRTRSGGGEIVAL 227
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286
+ GSA + A AG + AE L+ P + A +Y G +
Sbjct: 228 LK-TGSAYYAPAAAGIQMAESFLKDKKMILPCAAKVKAGMY--------------GLDED 272
Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+ +P + V I+ ++S +E + + ++ ++ + +
Sbjct: 273 LFVGVPTEISANGVRPIE----VEISDKEREQLQVSINAIKDLNKAAAEIL 319
>2LDB-A nrPDB
Length = 317
Score = 233 bits (595), Expect = 7e-62, Method: Composition-based stats.
Identities = 72/341 (21%), Positives = 121/341 (35%), Gaps = 40/341 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE--GIGKDLSHINTNSSCVGYDKD 60
+V ++GA G VG L E+ L D ++ G D +H +
Sbjct: 8 RVVVIGA-GFVGASYVFALMNQGIADEIVLIDANESKAIGDAMDFNHGKVFAPKPVDIWH 66
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ +A +V+I AG +KPG TR DL N I +S+V +V LV +NPV
Sbjct: 67 GDYDDCRDADLVVICAGANQKPGETRLDLVDKNIAIFRSIVESVMASGFQGLFLVATNPV 126
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYL-----MLKNPKIGQEQDK 174
+ L K V+G T LD R L +Y + IG+ D
Sbjct: 127 DILTY----ATWKFSGLPHERVIGSGTILDTARFRFLLGEYFSVAPQNVHAYIIGEHGDT 182
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234
IG ++ S + K E V+ +I++ K G+
Sbjct: 183 ELPVWSQAYIGVMPIRKLVE-----SKGEEAQKDLERIFVNVRDAAYQIIEKK---GATY 234
Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294
+A A+ +L + E L+ YL GL + Y +P V
Sbjct: 235 YGIAMGLARVTRAILHN------ENAILTVSAYLDGLYGERD----------VYIGVPAV 278
Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335
+ + + +L+ E+ + + L+ + + +
Sbjct: 279 INRNGIREVIEI---ELNDDEKNRFHHSAATLKSVLARAFT 316
>2LDX-A nrPDB
Length = 331
Score = 233 bits (594), Expect = 1e-61, Method: Composition-based stats.
Identities = 81/345 (23%), Positives = 148/345 (42%), Gaps = 45/345 (13%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYD--IRAAEGIGKDLSH--INTNSSCVGYD 58
K+ ++G G VG ++ + L ELAL D G DL H + ++ + +
Sbjct: 21 KITVVGV-GDVGMACAISILLKGLADELALVDADTDKLRGEALDLQHGSLFLSTPKIVFG 79
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
KD N +N+++V+I AG G TR DL + N I+K++V V + +P+ +I+V++N
Sbjct: 80 KD--YNVSANSKLVIITAGARMVSGQTRLDLLQRNVAIMKAIVPGVIQNSPDCKIIVVTN 137
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLML-----KNPKIGQEQ 172
PV+ L + + K+ F G V+G NLD R + + L + +G+
Sbjct: 138 PVDILTYV----VWKISGFPVGRVIGSGCNLDSARFRYLIGEKLGVNPTSCHGWVLGEHG 193
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHR-VQFGGDEIVKAKQGAG 231
D + + G + +++ P ++ +KQ+ +H+ V GG E++ K G
Sbjct: 194 DSSVPIWSGVNVAGVTLKSLNP-----AIGTDKNKQHWKNVHKQVVEGGYEVLDMK---G 245
Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291
+ ++ + A +L++ P T + F G + S+
Sbjct: 246 YTSWAIGLSVTDLARSILKNLKRVHPVTTLVKGF---------------HGIKEEVFLSI 290
Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
P VL I V ++ EE L+ + L N++K
Sbjct: 291 PCVLGESG---ITDFVKVNMTAEEEGLLKKSADTLW-NMQKNLEL 331
>1SOW-A nrPDB
Length = 328
Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats.
Identities = 76/344 (22%), Positives = 137/344 (39%), Gaps = 58/344 (16%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSC---VGYDK 59
K+A++G SG +G + L L ++ L+D+ GK L S V
Sbjct: 10 KIAMIG-SGMIGGTMGYLCVLRELA-DVVLFDVVTGMPEGKALDDSQATSIADTNVSVTS 67
Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+ ++ + VV+I AG+ + PG +R+DL NA I++ + V K+ P A ++
Sbjct: 68 ANQYEKIAGSDVVIITAGLTKVPGKSDKEWSRNDLLPFNAKIIREVAQGVKKYCPLAFVI 127
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQD 173
V++NP++ +V + + V G+ N LD R F+ D L + I
Sbjct: 128 VVTNPLDCMV----KCFHEASGLPKNMVCGMANVLDSARFRRFIADQLEISPRDI----- 178
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQ-----------LDKQYEHFIHRVQFGGDE 222
+ TVIG H G+ ++P+ ++ + + + R + G E
Sbjct: 179 ------QATVIGTH-GDHMLPLARYVTVNGFPLREFIKKGKMTEAKLAEIVERTKKAGGE 231
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
IV+ G GSA + A + A+ L+ P VY G
Sbjct: 232 IVRLL-GQGSAYYAPALSAITMAQAFLKDEKRVLPC------SVYCQGEYGLHDM----- 279
Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKEL 326
+ LP V+ G + + +L+ E++ +V ++
Sbjct: 280 -----FIGLPAVIGGGGIEQVIEL---ELTHEEQECFRKSVDDV 315
>1A5Z-A nrPDB
Length = 319
Score = 231 bits (590), Expect = 3e-61, Method: Composition-based stats.
Identities = 85/339 (25%), Positives = 134/339 (39%), Gaps = 45/339 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHI-NTNSSCVGYD 58
+K+ I+G G VG + L + + E+ L D+ AEG DL H Y
Sbjct: 1 MKIGIVGL-GRVGSSTAFALLMKGFAREMVLIDVDKKRAEGDALDLIHGTPFTRRANIYA 59
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
D L + VV++ AGVP+KPG TR L NA ++K + V K+AP++ ++V++N
Sbjct: 60 GD--YADLKGSDVVIVAAGVPQKPGETRLQLLGRNARVMKEIARNVSKYAPDSIVIVVTN 117
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLM-----LKNPKIGQEQ 172
PV+ L + K P V G T LD R T + + + IG+
Sbjct: 118 PVDVLTYFFL----KESGMDPRKVFGSGTVLDTARLRTLIAQHCGFSPRSVHVYVIGEHG 173
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQY-EHFIHRVQFGGDEIVKAKQGAG 231
D +IGG IP+ + + D + E+F + + EI++ K G
Sbjct: 174 DSEVPVWSGAMIGG------IPLQNMCQVCQKCDSKILENFAEKTKRAAYEIIERK---G 224
Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291
+ ++A A A E + E L+ VYL K S+
Sbjct: 225 ATHYAIALAVADIVESIFFD------EKRVLTLSVYLEDYLGVKDLC----------ISV 268
Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNI 330
P+ L V I L + + + L+ I
Sbjct: 269 PVTLGKHGVERILELNLNEEE---LEAFRKSASILKNAI 304
>4M1Q-A nrPDB
Length = 339
Score = 230 bits (585), Expect = 1e-60, Method: Composition-based stats.
Identities = 75/343 (21%), Positives = 125/343 (36%), Gaps = 42/343 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSH-INTNSSCVGYDK 59
+V I+G +G VG + + E+ L D+ EG DL+H I + +
Sbjct: 29 RVVIIG-TGAVGSSYAFSMINQNVTDEMVLIDLDKRKTEGDAMDLNHGIPFGAPTKVWAG 87
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
D +A +V+I AG +KPG TR DL + NA I K +V V N ++ +NP
Sbjct: 88 D--YGDCKSADIVVITAGAAQKPGETRLDLVEKNANIFKGIVDQVMGSGFNGIFIIATNP 145
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYL-----MLKNPKIGQEQD 173
V+ L K V+G T LD R L +Y + +G+ D
Sbjct: 146 VDVLAY----ATWKFSGLPKERVIGSGTILDTARFRFLLSEYFDIDVRNIHGYIMGEHGD 201
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233
T IG I DK +K + V+ I++ K G+
Sbjct: 202 TELPVWSQTRIGSEP----ISRYMDKYKPDGSNKDLDEIFVNVRDAAYHIIERK---GAT 254
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
++A A+ + +LR+ E L+ + G D Y +P
Sbjct: 255 HYAIAMGLARLTKAILRN------EQSILTVSTLMEGEY----------DLDDVYIGVPA 298
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
++ V L+ E + ++ + L+ ++
Sbjct: 299 IVSQKGVERAIEI---DLNDEEMKKLHHSSNTLKDVMKPIFDM 338
>6J9S-A nrPDB
Length = 326
Score = 226 bits (577), Expect = 7e-60, Method: Composition-based stats.
Identities = 79/341 (23%), Positives = 129/341 (37%), Gaps = 43/341 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHI-NTNSSCVGYDK 59
KV ++G G VG + + L E+ + DI +G DL S Y
Sbjct: 11 KVILVG-DGAVGSSYAYAMVLQGIAQEIGIVDIFKDKTKGDAIDLEDALPFTSPKKIYSA 69
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ + +A +V+I AG P+KPG TR DL N I+KS+V + N LV +NP
Sbjct: 70 E--YSDAKDADLVVITAGAPQKPGETRLDLVNKNLKILKSIVDPIVDSGFNGIFLVAANP 127
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLV-----DYLMLKNPKIGQEQD 173
V+ L K+ F V+G T+LD R + D + +G+ D
Sbjct: 128 VDILTY----ATWKLSGFPKNRVVGSGTSLDTARFRQSIAKMVNVDARSVHAYIMGEHGD 183
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233
IGG + + K+ + + V+ EI+K K G+
Sbjct: 184 TEFPVWSHANIGGVTIAEWV-----KAHPEIKEDKLVKMFEDVRNKAYEIIKLK---GAT 235
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+A A A+ ++ +L E L VY+ G + Y P
Sbjct: 236 FYGIATALARISKAILND------ENAVLPLSVYMDGQYG----------LNDIYIGTPA 279
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK 334
V+ + +I L+ EE+ + + +L+K +
Sbjct: 280 VINRNGIQNILEI---PLTDHEEESMQKSASQLKKVLTDAF 317
>4BGV-A nrPDB
Length = 323
Score = 226 bits (575), Expect = 1e-59, Method: Composition-based stats.
Identities = 82/350 (23%), Positives = 148/350 (42%), Gaps = 51/350 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K++++GA G VG ++ L + ++ ++DI GK L I + GYD
Sbjct: 4 KISVIGA-GAVGATVAQTLAIRQ-TGDIYIFDIVDGLAEGKALD-ILEGAPHWGYDLDIK 60
Query: 59 -----KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARI 113
+S + + V+++ AG+ RKPG++RDDL N GI+KS+ A+ K++P ++I
Sbjct: 61 GFCTADESKYAEMKGSDVIVVTAGLARKPGMSRDDLLLKNIGIMKSVGEAIKKYSPESKI 120
Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQ 172
+V++NP + + K P ++G+ LD R TFL L +
Sbjct: 121 VVVTNPADIMAYAIY----KASGISPERIIGLGGSLDSTRFRTFLAQELNV--------- 167
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKA 226
+ VIGGH G+ ++P I ++ ++ + + R +FGG EIV
Sbjct: 168 --SFEDVNAFVIGGH-GDDMVPFIRYSNVSGIPIEDLLPREKIDEIVKRTRFGGGEIVNL 224
Query: 227 KQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSI 286
+ GSA + + A E ++ P Y+ G + +
Sbjct: 225 YK-TGSAFYAPGISIAVMVESIVNDRKRVIPCA------AYITGEHSKTY------LVNN 271
Query: 287 EYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+ +PI + V I K + E + +V+ ++KN +
Sbjct: 272 LFIGVPIKIGKNGVEKIYDL---KFNEDELEAWKKSVESVKKNSAIADDY 318
>4Q3N-A nrPDB
Length = 314
Score = 224 bits (571), Expect = 4e-59, Method: Composition-based stats.
Identities = 78/325 (24%), Positives = 123/325 (37%), Gaps = 36/325 (11%)
Query: 15 QPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVV 72
+ + V EL L DI AEG DL+H K +A +V
Sbjct: 16 MSYAYAMVNQGTVEELVLLDIDKRKAEGEAMDLNHGLAFGPRKMSIKAGDYKDCKDAGLV 75
Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132
+I AGV +K G TR L K NA I+K++V + N +LV SNPV+ L +A K
Sbjct: 76 VITAGVNQKEGETRIHLLKRNAEIIKTVVKNIMSSGFNGILLVASNPVDVLAYVA---WK 132
Query: 133 KMGKFKPGNVMGVTNLDLVRAETFLVDYLM-----LKNPKIGQEQDKTTMHRKVTVIGGH 187
+ G + T+LD R + Y+ + +G+ D + +G
Sbjct: 133 ESGLHHSRVIGSGTSLDTARLRYEISQYIHIDSRNVHAYILGEHGDSEFVCWSNANVGAK 192
Query: 188 SGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEE 247
+I + + S + EH +V+ EI+ K+ + + A +
Sbjct: 193 PIADVIDSMDEISF-----EDLEHIYLKVRDAAYEIISRKK---ATYYGIGMALVRITAA 244
Query: 248 VLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSV 307
+ + + P L+ VY Y LP VL V I V
Sbjct: 245 IFNNENRILP-ISVLNNGVY--------------DCEDQVYIGLPAVLNKDGVHHI---V 286
Query: 308 LEKLSPREEQLVNTAVKELRKNIEK 332
KL+ +E +N + LRKN++
Sbjct: 287 KLKLNEKENSQLNNSANILRKNLDD 311
>6H9S-A nrPDB
Length = 307
Score = 223 bits (569), Expect = 6e-59, Method: Composition-based stats.
Identities = 77/344 (22%), Positives = 136/344 (39%), Gaps = 45/344 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDK 59
+K++I+G +G VG + L + E+ LYD+ AEG DL H T +
Sbjct: 1 MKISIIG-TGRVGSSTAFALINAAVADEIVLYDLNKEMAEGEALDLLHATTFHKRMIIRA 59
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ + + +VLI AG +KPG TR DL NA I+K + + K+APN I+ I+NP
Sbjct: 60 GEY-SDIEGSDIVLITAGAAQKPGETRLDLTIKNAKIIKGISENIKKYAPNTLIINITNP 118
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMG-VTNLDLVRAETFL-----VDYLMLKNPKIGQEQD 173
V+ + + + K+ F+ V+G T LD R + V + + IG+ D
Sbjct: 119 VDVMSYV----VWKVTGFESNRVIGTGTILDTARLRALIGKNCGVSPMSVHAYIIGEHGD 174
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233
+IGG + + +K V+ I+ K G+
Sbjct: 175 SELAAWSSAMIGGVPIKG---FCRNCPYKDNCNKDLSKIFDDVKNSAYTIISKK---GAT 228
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+A A E ++++ E + V L Y P
Sbjct: 229 NYGIASATTALVESIIKN------EGRVYTPSVLLD----------------DVYIGYPA 266
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
V+ V + ++ L+ E + ++ +++ +E K+ +
Sbjct: 267 VINKDGV---ERTIDITLNDEETEKFESSKSIIKEYLESIKNLL 307
>6CT6-A nrPDB
Length = 338
Score = 223 bits (569), Expect = 7e-59, Method: Composition-based stats.
Identities = 78/355 (21%), Positives = 147/355 (41%), Gaps = 48/355 (13%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSC---VGYDK 59
K+A++G SG +G ++ L L + ++ L+D+ +GK + + +S +
Sbjct: 11 KIALVG-SGMIGGTMAFLCSLKE-LGDVVLFDVVPNMPMGKAMDLCHNSSVVDNGITVYG 68
Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+ L+NA VV+I AG+ + PG +R DL +N I++ + A+ K+ PNA I+
Sbjct: 69 SNSYECLTNADVVIITAGITKIPGKSDKEWSRMDLLPVNIKIMREVGGAIKKYCPNAFII 128
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168
I+NP++ +V +++ + G+ LD R + D L + I
Sbjct: 129 NITNPLDVMV----AAVQEAANVPKHMICGMAGMLDSSRLRRMIADCLHVSPHDVQGMVI 184
Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228
G D + I G IPI + + + ++ + G +IV+
Sbjct: 185 GVHGDNMLPLMRYITING------IPIQEFINKGLINKEDINNIYNKTKQAGGDIVRLL- 237
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
G GSA + + AE L+ + YL G N Y
Sbjct: 238 GQGSAYYAPGTSAILMAESYLKDKKR------LFVSSCYLNGQYNVNN----------HY 281
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSSKL 343
+P ++ + I L+ E++L+ ++ E+ + ++K + LD+ KL
Sbjct: 282 LGVPCIIGGKGIEQIIEL---DLNQEEKKLLQGSIDEVLE-MQKAIA-ALDAGKL 331
>1UXJ-A nrPDB
Length = 309
Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats.
Identities = 89/345 (25%), Positives = 152/345 (44%), Gaps = 50/345 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD---- 58
K++I+GA G VG + L + ++ L DI GK L + S G+D
Sbjct: 4 KISIIGA-GFVGSTTAHWLAAKE-LGDIVLLDIVEGVPQGKALD-LYEASPIEGFDVRVT 60
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ +N+ V+++ +G PRKPG++R+DL K+NA I ++ ++ +PNA I++++N
Sbjct: 61 GTNNYADTANSDVIVVTSGAPRKPGMSREDLIKVNADITRACISQAAPLSPNAVIIMVNN 120
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++++ +A E F V+G LD R TF+ E +
Sbjct: 121 PLDAMTYLAAEV----SGFPKERVIGQAGVLDAARYRTFIA-----------MEAGVSVK 165
Query: 178 HRKVTVIGGHSGETIIPIITDKSLV------FQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231
+ ++GGH G+ ++P+ ++ F + + R + GG EIV + G
Sbjct: 166 DVQAMLMGGH-GDEMVPLPRFSTISGIPVSEFIAPDRLAQIVERTRKGGGEIVNLLK-TG 223
Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291
SA + A A A+ E VL+ P YL G + YF +
Sbjct: 224 SAYYAPAAATAQMVEAVLKDKKRVMPVA------AYLTGQYG----------LNDIYFGV 267
Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
P++L G V I L+ E L+N + K +R ++ KS
Sbjct: 268 PVILGAGGVEKILEL---PLNEEEMALLNASAKAVRATLDTLKSL 309
>3NEP-X nrPDB
Length = 314
Score = 218 bits (554), Expect = 4e-57, Method: Composition-based stats.
Identities = 78/346 (22%), Positives = 141/346 (40%), Gaps = 50/346 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYD--- 58
+KV ++GA G VG ++ + E+ + DI+ GK L + +S G+D
Sbjct: 1 MKVTVIGA-GNVGATVAECVARQDVAKEVVMVDIKDGMPQGKALD-MRESSPIHGFDTRV 58
Query: 59 -KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
+ ++ V +I AG+PR PG++RDDL N IV + + +P++ I+V++
Sbjct: 59 TGTNDYGPTEDSDVCIITAGLPRSPGMSRDDLLAKNTEIVGGVTEQFVEGSPDSTIIVVA 118
Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
NP++ + +A E F VMG+ LD R +F+ + L D +
Sbjct: 119 NPLDVMTYVAYE----ASGFPTNRVMGMAGVLDTGRFRSFIAEEL-----------DVSV 163
Query: 177 MHRKVTVIGGHSGETIIPIITDKSLVFQL------DKQYEHFIHRVQFGGDEIVKAKQGA 230
+ ++GGH G+T++P+ ++ D + E + R + G EIV
Sbjct: 164 RDVQALLMGGH-GDTMVPLPRYTTVGGIPVPQLIDDARIEEIVERTKGAGGEIVDL--MG 220
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290
SA + A A+ E +L+ P Y G +
Sbjct: 221 TSAWYAPGAAAAEMTEAILKDNKRILPCA------AYCDGEYG----------LDDLFIG 264
Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+P+ L G V + L E+ + T+ + N++ +
Sbjct: 265 VPVKLGAGGVEEVIEV---DLDADEKAQLKTSAGHVHSNLDDLQRL 307
>1Y6J-A nrPDB
Length = 318
Score = 217 bits (553), Expect = 5e-57, Method: Composition-based stats.
Identities = 77/342 (22%), Positives = 138/342 (40%), Gaps = 40/342 (11%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE--GIGKDLSHINTNSSCVGYDKD 60
KVAI+GA G VG + + L +EL L D+ + G D++H +
Sbjct: 9 KVAIIGA-GFVGASAAFTMALRQTANELVLIDVFKEKAIGEAMDINHGLPFMGQMSLYAG 67
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ + + V+++ AG RKPG TR DL K N I K + + K+ + ILV+SNPV
Sbjct: 68 DY-SDVKDCDVIVVTAGANRKPGETRLDLAKKNVMIAKEVTQNIMKYYNHGVILVVSNPV 126
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLM-----LKNPKIGQEQDK 174
+ + ++K G V+G T LD +R L + L + IG+ D
Sbjct: 127 DIITY----MIQKWSGLPVGKVIGSGTVLDSIRFRYLLSEKLGVDVKNVHGYIIGEHGDS 182
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSAT 234
T I G + I D ++ + V+ G I+K K G+
Sbjct: 183 QLPLWSCTHIAGKNINEYI----DDPKCNFTEEDKKKIAEDVKTAGATIIKNK---GATY 235
Query: 235 LSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIV 294
+A + E +L++ + + ++ + SLP +
Sbjct: 236 YGIAVSINTIVETLLKNQNTIRTVGTVINGMYGIE----------------DVAISLPSI 279
Query: 295 LRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+ + V + L+P EE+ + + ++++K + + K+
Sbjct: 280 VNSEGVQEVLQF---NLTPEEEEALRFSAEQVKKVLNEVKNL 318
>3WSV-A nrPDB
Length = 322
Score = 214 bits (545), Expect = 5e-56, Method: Composition-based stats.
Identities = 73/339 (21%), Positives = 131/339 (38%), Gaps = 42/339 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSH---INTNSSCVGYDK 59
KV I+G +G VG ++ + +EL L D+ + G+ L + V
Sbjct: 7 KVVIVG-TGFVGTSIAYAMINQGVANELVLIDVNQEKAEGEALDLLDGMAWGEKNVSVWS 65
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ E +A +V++ AGV +KPG TR DL K NA I + +V V + +V SNP
Sbjct: 66 GTYEE-CQDANLVILTAGVNQKPGQTRLDLVKTNATITRQIVKEVMASGFDGIFVVASNP 124
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLV-----DYLMLKNPKIGQEQDK 174
V+ L + T ++ G V T LD R + D + +G+ D
Sbjct: 125 VDILTYL---TWQESGLPASRVVGTGTTLDTTRFRKEIALKLAVDPRSVHGYILGEHGDS 181
Query: 175 TTMHRKVTVIGGHSGETIIPIITDKSLVFQLDK-QYEHFIHRVQFGGDEIVKAKQGAGSA 233
T +GG PI+ +L++ +V+ EI+ K+ +
Sbjct: 182 EVAAWSHTTVGGK------PIMEYVEKDHRLEENDLTVLADKVKNAAYEIIDRKK---AT 232
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+ + + + +L + E L YL G + +P
Sbjct: 233 YYGIGMSTTRIVKAILNN------EQAVLPVSAYLNGEYG----------EEDIFTGVPS 276
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEK 332
++ V I + +P+E+ + + +V EL+ ++
Sbjct: 277 IVDENGVREIIDLSI---TPQEKAMFHQSVSELKAVLDT 312
>1EZ4-A nrPDB
Length = 318
Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats.
Identities = 71/341 (20%), Positives = 116/341 (34%), Gaps = 44/341 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHI-NTNSSCVGYDK 59
KV ++G G VG + + E + D+ +G DL + Y
Sbjct: 7 KVVLVG-DGAVGSSYAFAMAQQGIAEEFVIVDVVKDRTKGDALDLEDAQAFTAPKKIYSG 65
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ + +A +V+I AG P+KPG +R DL N I+ S+V V + LV +NP
Sbjct: 66 E--YSDCKDADLVVITAGAPQKPGESRLDLVNKNLNILSSIVKPVVDSGFDGIFLVAANP 123
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKI-----GQEQD 173
V+ L K F V+G T+LD R L + + G+ D
Sbjct: 124 VDILTY----ATWKFSGFPKERVIGSGTSLDSSRLRVALGKQFNVDPRSVDAYIMGEHGD 179
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSA 233
IG P+ D V+ +I+ K G+
Sbjct: 180 SEFAAYSTATIGT------RPVRDVAKEQGVSDDDLAKLEDGVRNKAYDIINLK---GAT 230
Query: 234 TLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPI 293
+ A + ++ +LR E L Y+ G + Y P
Sbjct: 231 FYGIGTALMRISKAILRD------ENAVLPVGAYMDGQYG----------LNDIYIGTPA 274
Query: 294 VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGK 334
++ + I S LS E + + + L+K + G
Sbjct: 275 IIGGTGLKQIIES---PLSADELKKMQDSAATLKKVLNDGL 312
>3ZZN-A nrPDB
Length = 310
Score = 208 bits (530), Expect = 2e-54, Method: Composition-based stats.
Identities = 78/337 (23%), Positives = 127/337 (37%), Gaps = 44/337 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDK 59
+KV I+G SG VG + L L E+ L D+ A+ +D+ H + V
Sbjct: 1 MKVGIVG-SGMVGSATAYALALLGVAREVVLVDLDRKLAQAHAEDILHATPFAHPVWVWA 59
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
S L A+ V++ AGV ++PG TR L NA + +V V + AP A +LV +NP
Sbjct: 60 GSY-GDLEGARAVVLAAGVAQRPGETRLQLLDRNAQVFAQVVPRVLEAAPEAVLLVATNP 118
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYL-----MLKNPKIGQEQD 173
V+ + +A + PG V+G T LD R L +YL + +G+ D
Sbjct: 119 VDVMTQVAYA----LSGLPPGRVVGSGTILDTARFRALLAEYLRVAPQSVHAYVLGEHGD 174
Query: 174 KTTMHRKVTVIGGHSGETIIPI--ITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAG 231
+ +GG +P+ + + V+ I++ K G
Sbjct: 175 SEVLVWSSAQVGG------VPLLEFAEARGRALSPEDRARIDEGVRRAAYRIIEGK---G 225
Query: 232 SATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSL 291
+ + A+ +L G+ V SL
Sbjct: 226 ATYYGIGAGLARLVRAILTDEK----------------GVYTVSAFTPEVAGVLEVSLSL 269
Query: 292 PIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRK 328
P +L G V +V LSP E + + + L++
Sbjct: 270 PRILGAGGVA---GTVYPSLSPEERAALRRSAEILKE 303
>5MDH-A nrPDB
Length = 333
Score = 208 bits (529), Expect = 3e-54, Method: Composition-based stats.
Identities = 75/358 (20%), Positives = 130/358 (36%), Gaps = 53/358 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDIRAAEGIG----KDLSHINTNS 52
++V + GA+G + L + + L L DI G+ +L
Sbjct: 4 IRVLVTGAAGQIAYSLLYSIGNGSVFGKDQPIILVLLDITPMMGVLDGVLMELQDCALPL 63
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA- 111
D E + V ++ +PR+ G+ R DL K N I K A+ K+A +
Sbjct: 64 LKDVIATDKEEIAFKDLDVAILVGSMPRRDGMERKDLLKANVKIFKCQGAALDKYAKKSV 123
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171
+++V+ NP N+ A K N +T LD RA+ + L + + +
Sbjct: 124 KVIVVGNPANTNCLTAS---KSAPSIPKENFSCLTRLDHNRAKAQIALKLGVTSDDV--- 177
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDK------------QYEHFIHRVQFG 219
+ V + G HS T P + + Q + FI VQ
Sbjct: 178 -------KNVIIWGNHS-STQYPDVNHAKVKLQAKEVGVYEAVKDDSWLKGEFITTVQQR 229
Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQ 279
G ++KA++ LS A + AK + +R PE E +S + G G
Sbjct: 230 GAAVIKARK------LSSAMSAAKAICDHVRDIWFGTPEGEFVSMGIISDGNSYG----- 278
Query: 280 LVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
+S P+ +++ + ++ + S + L KEL + E F+
Sbjct: 279 ---VPDDLLYSFPVTIKDKTWKIVEGLPINDFSREKMDL---TAKELAEEKETAFEFL 330
>4UUP-A nrPDB
Length = 341
Score = 201 bits (511), Expect = 4e-52, Method: Composition-based stats.
Identities = 78/349 (22%), Positives = 137/349 (39%), Gaps = 48/349 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE----LALYDI----RAAEGIGKDLSHINTNSS 53
+ V I GA+G +G L+ + + L L +I +A EG+ +L +
Sbjct: 5 IHVLITGAAGQIGYALAFRIAKGDLFGDRKVVLHLLEIPPAMKALEGVCMELQDCAFPTL 64
Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNAR 112
D E + V + PRKPG+ R DL + NAGI K A+ ++A P +
Sbjct: 65 AGVVATDDPEEAFKDVDVAFLVGSFPRKPGMERADLLEKNAGIFKVQGKALSEYAKPTVK 124
Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172
+LV+ NP N+ IA+ K+G P N +T LD RA + L + K+
Sbjct: 125 VLVVGNPANTNCLIAMANAPKLG---PENFSAMTRLDHNRAIGEIAAKLGVPVDKV---- 177
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITD---------KSLVFQLDKQY--EHFIHRVQFGGD 221
V V G HS T +P ++ K + L K+Y F+ ++ G
Sbjct: 178 ------HNVVVWGNHS-NTQVPDVSHATVDKEGGTKKVSDALPKEYLEGEFVQKIAQRGG 230
Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281
+++A+ + A + A A +R + + +S + +P
Sbjct: 231 AVIEARGAS------SAASAANAALCHMRDWLFGTKPGDWVSMGIPVP-------EGNPY 277
Query: 282 GDNSIEYFSLPIVL-RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKN 329
G +S P + ++G V ++ + + + + E R+
Sbjct: 278 GIKPGVIYSFPCTVDKDGKVHIVEGLEINDWVREKMEATEKELIEERET 326
>1PZF-A nrPDB
Length = 331
Score = 196 bits (498), Expect = 1e-50, Method: Composition-based stats.
Identities = 75/322 (23%), Positives = 131/322 (40%), Gaps = 56/322 (17%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINT--NSSCVGYD 58
KVA++G SG +G + L L ++ LYD+ EG DLSH+ + +++
Sbjct: 11 KVAMIG-SGMIGGTMGYLCALRELA-DVVLYDVVKGMPEGKALDLSHVTSVVDTNVSVRA 68
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARI 113
+ S E L+ A V++ AG+ + PG +R+DL N+ I++ + + K+ P I
Sbjct: 69 EYSYEAALTGADCVIVTAGLTKVPGKPDSEWSRNDLLPFNSKIIREIGQNIKKYCPKTFI 128
Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQ 172
+V++NP++ +V + E + G+ LD R ++ D L + +
Sbjct: 129 IVVTNPLDCMVKVMCE----ASGVPTNMICGMACMLDSGRFRRYVADALSVSPRDV---- 180
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVF-----------QLDKQYEHFIHRVQFGGD 221
+ TVIG H G+ ++P++ ++ +KQ E + G
Sbjct: 181 -------QATVIGTH-GDCMVPLVRYITVNGYPIQKFIKDGVVTEKQLEEIAEHTKVSGG 232
Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281
EIV+ G GSA + A + A L P VY G K
Sbjct: 233 EIVRFL-GQGSAYYAPAASAVAMATSFLNDEKRVIPC------SVYCNGEYGLKDM---- 281
Query: 282 GDNSIEYFSLPIVLRNGSVVSI 303
+ LP V+ + +
Sbjct: 282 ------FIGLPAVIGGAGIERV 297
>1T24-A nrPDB
Length = 322
Score = 196 bits (497), Expect = 1e-50, Method: Composition-based stats.
Identities = 74/340 (21%), Positives = 134/340 (39%), Gaps = 48/340 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG---YDK 59
K+ ++G SG +G ++ L+ + + ++ L+DI GK L +TN
Sbjct: 6 KIVLVG-SGMIGGVMATLI-VQKNLGDVVLFDIVKNMPHGKALDTSHTNVMAYSNCKVSG 63
Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+ + L+ A VV++ AG + PG RDDL +N I+ + + K PNA I+
Sbjct: 64 SNTYDDLAGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKKNCPNAFII 123
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168
V++NPV+ +V + L + ++G+ LD R + ++ L + +
Sbjct: 124 VVTNPVDVMVQL----LHQHSGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNAHIV 179
Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228
G +K + ++ +GG IP+ + D + E R EIV
Sbjct: 180 GAHGNKMVLLKRYITVGG------IPLQEFINNKLISDAELEAIFDRTVNTALEIVNLHA 233
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
S ++ A A + AE L+ L L G S +
Sbjct: 234 ---SPYVAPAAAIIEMAESYLKDLKKV------LICSTLLEGQYGH----------SDIF 274
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRK 328
P+VL V + +L+ E+ + A+ E ++
Sbjct: 275 GGTPVVLGANGVEQVIEL---QLNSEEKAKFDEAIAETKR 311
>3LDH-A nrPDB
Length = 330
Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats.
Identities = 67/354 (18%), Positives = 125/354 (35%), Gaps = 66/354 (18%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIR--AAEGIGKDLSHINTNSSCVGYDKD 60
K+ ++G VG ++ + + E+AL D+ +G DL H +
Sbjct: 23 KITVVGCD-AVGMADAISVLMKDLADEVALVDVMEDKLKGEMMDLEHGSLFLHTAKIVSG 81
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
+ + +++V+I AG ++ G +R +L + N I K ++ + K +P+ L +P
Sbjct: 82 KDYSVSAGSKLVVITAGARQQEGESRLNLVQRNVNIFKFIIPNIVKHSPDC--LKELHP- 138
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
L + K+ ++G NLD R + + L + +
Sbjct: 139 -ELGTDKNKQDWKLSGLPMHRIIGSGCNLDSARFRYLMGERLGVH-----------SCLV 186
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
VIG H G+++ + + V E++K K G + ++
Sbjct: 187 IGWVIGQH-GDSVPSVWSGMW--------DAKLHKDVVDSAYEVIKLK---GYTSWAIGL 234
Query: 240 -----------------AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
+ A A+ +++ P + + F G
Sbjct: 235 VVSNPVDVLTYVAWKGCSVADLAQTIMKDLCRVHPVSTMVKDF---------------YG 279
Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+ SLP VL NG V KL P EEQ + + L +I+K F
Sbjct: 280 IKDNVFLSLPCVLNNGISHCN--IVKMKLKPDEEQQLQKSATTLW-DIQKDLKF 330
>5NFR-A nrPDB
Length = 320
Score = 193 bits (490), Expect = 9e-50, Method: Composition-based stats.
Identities = 79/353 (22%), Positives = 146/353 (41%), Gaps = 57/353 (16%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINT--NSSCVG 56
M K+A++G SG +G + L L + +L LYD+ +G DL H +T +
Sbjct: 1 MTKIALIG-SGQIGAIVGELCLL-ENLGDLILYDVVPGIPQGKALDLKHFSTILGVNRNI 58
Query: 57 YDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ IE+ + +A +++I AGV RK G+TR+DL +N I+KS+ +V A ++ +
Sbjct: 59 LGTNQIED-IKDADIIVITAGVQRKEGMTREDLIGVNGKIMKSVAESVKLHCSKAFVICV 117
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKT 175
SNP++ +V + K + G+ LD R + + D L + +
Sbjct: 118 SNPLDIMVNV----FHKFSNLPHEKICGMAGILDTSRYCSLIADKLKVSAEDV------- 166
Query: 176 TMHRKVTVIGGHSGETIIPIITDKSLVF-----------QLDKQYEHFIHRVQFGGDEIV 224
++GGH G+ ++P+ S+ + + I + + G EI+
Sbjct: 167 ----NAVILGGH-GDLMVPLQRYTSVNGVPLSEFVKKNMISQNEIQEIIQKTRNMGAEII 221
Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284
K + + A + A A K + L + +N + VYL G N
Sbjct: 222 KLAKAS--AAFAPAAAITKMIKSYLYNENN------LFTCAVYLNGHYN----------C 263
Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
S + + N ++ L+ E+ L ++ ++ N +K I
Sbjct: 264 SNLFVGSTAKINNKGAHPVEF----PLTKEEQDLYTESIASVQSNTQKAFDLI 312
>5HTO-A nrPDB
Length = 346
Score = 193 bits (490), Expect = 1e-49, Method: Composition-based stats.
Identities = 69/340 (20%), Positives = 131/340 (38%), Gaps = 48/340 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG---YDK 59
K+ ++G SG +G ++ L+ + + ++ ++D+ GK L ++N
Sbjct: 36 KIVLVG-SGMIGGVMATLI-VQKNLGDVVMFDVVKNMPQGKALDTSHSNVMAYSNCKVTG 93
Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+ + L A VV++ AG + PG RDDL +N I+ + + PNA I+
Sbjct: 94 SNSYDDLKGADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNLCPNAFII 153
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168
V++NPV+ +V + E ++G+ LD R + ++ L + +
Sbjct: 154 VVTNPVDVMVQLLFEH----SGVPKNKIIGLGGVLDTSRLKYYISQKLNVCPRDVNALIV 209
Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228
G +K + ++ +GG IP+ + D++ E R EIV
Sbjct: 210 GAHGNKMVLLKRYITVGG------IPLQEFINNKKITDEEVEGIFDRTVNTALEIVNLLA 263
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
S ++ A A + AE L+ L L G +
Sbjct: 264 ---SPYVAPAAAIIEMAESYLKDIKKV------LVCSTLLEGQYGHSN----------IF 304
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRK 328
P+V+ V + +L+ E+ + AV E ++
Sbjct: 305 GGTPLVIGGTGVEQVIEL---QLNAEEKTKFDEAVAETKR 341
>1HYE-A nrPDB
Length = 313
Score = 193 bits (489), Expect = 1e-49, Method: Composition-based stats.
Identities = 88/348 (25%), Positives = 148/348 (42%), Gaps = 48/348 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALY----DIRAAEGIGKDL--SHINTNSSCV 55
+KV I+GASG VG +LLL P++ +L L I EG+ +D+ + T S
Sbjct: 1 MKVTIIGASGRVGSATALLLAKEPFMKDLVLIGREHSINKLEGLREDIYDALAGTRSDAN 60
Query: 56 GY-DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
Y + D + + VV+I +GVPRK G++R DL K NA IV + + + +I
Sbjct: 61 IYVESDENLRIIDESDVVIITSGVPRKEGMSRMDLAKTNAKIVGKYAKKIAEIC-DTKIF 119
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLK-----NPKI 168
VI+NPV+ + A+ KF+ V G+ T+LD +R + + + + I
Sbjct: 120 VITNPVDVMTYKALVD----SKFERNQVFGLGTHLDSLRFKVAIAKFFGVHIDEVRTRII 175
Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228
G+ D T IGG IPI + + I V+ G++I++ K
Sbjct: 176 GEHGDSMVPLLSATSIGG------IPIQKFERFKELP---IDEIIEDVKTKGEQIIRLKG 226
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
G+ F A V+R N + +LSA Y+ G +G
Sbjct: 227 GS-------EFGPAAAILNVVRCIVNNEKRLLTLSA--YVDGEFDG---------IRDVC 268
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSF 336
+P+ + + + + +L E + + ++K E+ K+
Sbjct: 269 IGVPVKIGRDGIEEVVSI---ELDKDEIIAFRKSAEIIKKYCEEVKNL 313
>1OC4-A nrPDB
Length = 322
Score = 193 bits (489), Expect = 1e-49, Method: Composition-based stats.
Identities = 71/337 (21%), Positives = 133/337 (39%), Gaps = 48/337 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG---YDK 59
K+ ++G SG +G ++ L+ + + ++ ++DI GK L +TN
Sbjct: 6 KIVLVG-SGMIGGVMATLI-VQKNLGDVVMFDIVKNMPHGKALDTSHTNVMAYSNCKVSG 63
Query: 60 DSIENTLSNAQVVLIPAGVPRKPG-----LTRDDLFKMNAGIVKSLVTAVGKFAPNARIL 114
+ + L +A VV++ AG + PG RDDL +N I+ + + PNA I+
Sbjct: 64 SNTYDDLKDADVVIVTAGFTKAPGKSDKEWNRDDLLPLNNKIMIEIGGHIKNNCPNAFII 123
Query: 115 VISNPVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----I 168
V++NPV+ +V + L + ++G+ LD R + ++ L + +
Sbjct: 124 VVTNPVDVMVQL----LHQHSGVPKNKIVGLGGVLDTSRLKYYISQKLNVCPRDVNAHIV 179
Query: 169 GQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQ 228
G +K + ++ +GG IP+ + D++ + R EIV
Sbjct: 180 GAHGNKMVLLKRYITVGG------IPLQEFINNKKITDQELDAIFDRTINTALEIVNLHA 233
Query: 229 GAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY 288
S ++ A A + AE +R L L G K +
Sbjct: 234 ---SPYVAPAAAIIEMAESYIRDLRKV------LICSTLLEGQYGHKD----------IF 274
Query: 289 FSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKE 325
P+V+ V + +L+ E++ + AV E
Sbjct: 275 AGTPLVIGGNGVEQVIEL---QLNADEKKKFDEAVAE 308
>5NUE-A nrPDB
Length = 332
Score = 192 bits (488), Expect = 1e-49, Method: Composition-based stats.
Identities = 77/356 (21%), Positives = 134/356 (37%), Gaps = 54/356 (15%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDIR----AAEGIGKDLSHINTNS 52
V+V + GA+G +G L ++ + L + DI A G+ +L
Sbjct: 6 VRVLVTGAAGQIGYALVPMIARGIMLGADQPVILHMLDIPPAAEALNGVKMELIDAAFPL 65
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKF-APNA 111
+ V ++ G PRK G+ R D+ N I KS A+ K APN
Sbjct: 66 LKGVVATTDAVEGCTGVNVAVMVGGFPRKEGMERKDVMSKNVSIYKSQAAALEKHAAPNC 125
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171
++LV++NP N+ I E N+ +T LD RA + + L + +
Sbjct: 126 KVLVVANPANTNALILKE---FAPSIPEKNISCLTRLDHNRALGQISERLSVPVSDV--- 179
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQ------------YEHFIHRVQFG 219
+ V + G HS + P + + ++ FI VQ
Sbjct: 180 -------KNVIIWGNHS-SSQYPDVNHAKVQTSSGEKPVRELVKDDAWLDGEFISTVQQR 231
Query: 220 GDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQ 279
G I+KA++ + A + A A + +R + PE +S VY G +
Sbjct: 232 GAAIIKARKLS------SALSAASSACDHIRDWVLGTPEGTFVSMGVYSDGSYSVPSGL- 284
Query: 280 LVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335
+S P+ RNG + ++++S ++ L +EL++ + S
Sbjct: 285 --------IYSFPVTCRNGDWSIVQGLPIDEVSRKKMDL---TAEELKEEKDLAYS 329
>2V6B-A nrPDB
Length = 304
Score = 190 bits (482), Expect = 9e-49, Method: Composition-based stats.
Identities = 68/321 (21%), Positives = 118/321 (36%), Gaps = 33/321 (10%)
Query: 15 QPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVV 72
+ L L SEL L D A+ +D++H S + L++AQVV
Sbjct: 13 STAAFALVLRGSCSELVLVDRDEDRAQAEAEDIAHAAPVSHGTRVW-HGGHSELADAQVV 71
Query: 73 LIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK 132
++ AG +KPG +R DL + NA I + LV + + AP+A +LV SNPV+ L +A +
Sbjct: 72 ILTAGANQKPGESRLDLLEKNADIFRELVPQITRAAPDAVLLVTSNPVDLLTDLATQLAP 131
Query: 133 KMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETI 192
G V+ + A+ VD +G+ D + ++ G
Sbjct: 132 GQPVIGSGTVLDSARFRHLMAQHAGVDGTHAHGYVLGEHGDSEVLAWSSAMVAGMP---- 187
Query: 193 IPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVLRSF 252
+ + ++ + I++ K+ + + A A+ E VLR
Sbjct: 188 VADFMQAQNLPWNEQVRAKIDEGTRNAAASIIEGKR---ATYYGIGAALARITEAVLRDR 244
Query: 253 HNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLEKLS 312
+ + SLP V+ V+S KL+
Sbjct: 245 RAVLTVSAPTPEY--------------------GVSLSLPRVVGRQGVLSTLHP---KLT 281
Query: 313 PREEQLVNTAVKELRKNIEKG 333
E+Q + + LR ++
Sbjct: 282 GDEQQKLEQSAGVLRGFKQQL 302
>4ND4-A nrPDB
Length = 321
Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats.
Identities = 71/335 (21%), Positives = 137/335 (40%), Gaps = 43/335 (12%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSH--INTNSSCVGYD 58
K+A++G SG +G ++ + ++++ L+DI +G D++H + S+
Sbjct: 6 KIAVIG-SGQIGGNIAY-IVGKDNLADVVLFDIAEGIPQGKALDITHSMVMFGSTSKVIG 63
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ + +S + VV+I A +P +P R +L NA I+ S+ V K+ PNA ++ I+N
Sbjct: 64 TNDYAD-ISGSDVVIITASIPGRPKDDRSELLFGNARILDSVAEGVKKYCPNAFVICITN 122
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPK-----IGQEQ 172
P++ +V +K+ V G+ LD R TF+ + + IG
Sbjct: 123 PLDVMV----SHFQKVSGLPHNKVCGMAGVLDSSRFRTFIAQHFGVNASDVSANVIGGHG 178
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232
D +GG +P+ + +Q + + + E+ + G+
Sbjct: 179 DGMVPATSSVSVGG------VPLSSFIKQGLITQEQIDEIVCHTRIAWKEVADNLK-TGT 231
Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292
A + A A K AE L+ P + S + G+ Y +P
Sbjct: 232 AYFAPAAAAVKMAEAYLKDKKAVVPCSAFCSNHYGVKGI----------------YMGVP 275
Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELR 327
++ V I L+P E++L+ ++ E+
Sbjct: 276 TIIGKNGVEDILEL---DLTPLEQKLLGESINEVN 307
>3FI9-A nrPDB
Length = 343
Score = 189 bits (481), Expect = 1e-48, Method: Composition-based stats.
Identities = 65/332 (19%), Positives = 126/332 (37%), Gaps = 29/332 (8%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKD 60
K+ I+GA+G +G ++ + L LYD A EG+ +++ H + + D
Sbjct: 10 KLTIVGAAGMIGSNMAQTAAMMRLTPNLCLYDPFAVGLEGVAEEIRHCGFEGLNLTFTSD 69
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNAR-ILVISNP 119
I+ L++A+ ++ G PRK G+TR+DL K NA I L + + P+ + +++I NP
Sbjct: 70 -IKEALTDAKYIVSSGGAPRKEGMTREDLLKGNAEIAAQLGKDIKSYCPDCKHVIIIFNP 128
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
+ + + KP V + LD R ++ L + +K + +
Sbjct: 129 ADITGLVTLIY----SGLKPSQVTTLAGLDSTRLQSELAKHFGIKQSLVTNTRTYGGHGE 184
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAF 239
++ V + P+ ++Q+ RV GG I+K + S+ S ++
Sbjct: 185 QMAVFASTAKVNGTPLTDLIGTDKLTNEQWAELKQRVVKGGANIIKLRGR--SSFQSPSY 242
Query: 240 AGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGS 299
+ + E A Y+ V ++ +
Sbjct: 243 VSIEMIRAAMG------GEAFRWPAGCYVN-----------VPGFEHIMMAMETTITKDG 285
Query: 300 VVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331
V D + L + E + + L K +
Sbjct: 286 VKHSDINQLG--NEAERAALKESYSHLAKLRD 315
>4I1I-A nrPDB
Length = 345
Score = 187 bits (474), Expect = 7e-48, Method: Composition-based stats.
Identities = 82/345 (23%), Positives = 135/345 (39%), Gaps = 47/345 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVS-----ELALYDI----RAAEGIGKDLSHINTNS 52
VKVA+ GA+G +G L L+ + EL L DI +A G+ +L
Sbjct: 25 VKVAVTGAAGQIGYALVPLIARGALLGPTTPVELRLLDIEPALKALAGVEAELEDCAFPL 84
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKF-APNA 111
+ ++ PRK G+ R DL +MNA I K A+ A +
Sbjct: 85 LDKVVVTADPRVAFDGVAIAIMCGAFPRKAGMERKDLLEMNARIFKEQGEAIAAVAASDC 144
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171
R++V+ NP N+ I +++ + GK P +V +T LD RA + L + ++
Sbjct: 145 RVVVVGNPANTNALILLKSAQ--GKLNPRHVTAMTRLDHNRALSLLARKAGVPVSQV--- 199
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSL-------VFQLDKQYEHFIHRVQFGGDEIV 224
R V + G HS T +P + + D + F+ V+ G EI+
Sbjct: 200 -------RNVIIWGNHS-STQVPDTDSAVIGTTPAREAIKDDALDDDFVQVVRGRGAEII 251
Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284
+ + LS A + AK A + + + + PE +S VY G
Sbjct: 252 QLRG------LSSAMSAAKAAVDHVHDWIHGTPEGVYVSMGVYSDENPYG--------VP 297
Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKN 329
S FS P G + + L +Q + + + EL++
Sbjct: 298 SGLIFSFPCTCHAGEWTVVSGKLNGDLG---KQRLASTIAELQEE 339
>2D4A-B nrPDB
Length = 308
Score = 186 bits (472), Expect = 1e-47, Method: Composition-based stats.
Identities = 66/338 (19%), Positives = 127/338 (37%), Gaps = 45/338 (13%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIR-AAEGIGKDLSHINTNSSCVG-YDKDS 61
+ ILGA G VG +++L + Y L + +G DL+H +
Sbjct: 2 ITILGA-GKVGMATAVMLMMRGYDDLLLIARTPGKPQGEALDLAHAAAELGVDIRISGSN 60
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+ + +VL+ AG+ RKPG+TR+ L + NA + L + +A +A +++ +NPV+
Sbjct: 61 SYEDMRGSDIVLVTAGIGRKPGMTREQLLEANANTMADLAEKIKAYAKDAIVVITTNPVD 120
Query: 122 SLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLK-----NPKIGQEQDKT 175
++ + K F V+G + LD R ++ L + +G K
Sbjct: 121 AMTYVMY----KKTGFPRERVIGFSGILDSARMAYYISQKLGVSFKSVNAIVLGMHGQKM 176
Query: 176 TMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATL 235
+++ +GG E ++ ++ E + G +I + + S+
Sbjct: 177 FPVPRLSSVGGVPLEHLM-----------SKEEIEEVVSETVNAGAKITELRGY--SSNY 223
Query: 236 SMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL 295
A E + R P +YL G +P V+
Sbjct: 224 GPAAGLVLTVEAIKRDSKRIYPY------SLYLQGEYGYNDIVAE----------VPAVI 267
Query: 296 RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKG 333
+ I L+ E++ + AV+ ++K +E
Sbjct: 268 GKSGIERIIEL---PLTEDEKRKFDEAVQAVKKLVETL 302
>4UUO-A nrPDB
Length = 340
Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats.
Identities = 75/356 (21%), Positives = 129/356 (36%), Gaps = 49/356 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE----LALYDI----RAAEGIGKDLSHINTNSS 53
+ + I GA+G +G L+ + + L L +I +A EG +L +
Sbjct: 4 IHILITGAAGQIGYALTFRIAKGDLCGDRKVVLHLLEIPFGMKALEGCVMELQDCAFPNV 63
Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNAR 112
D +E V + PRK G+ R DL N GI A+ +A P +
Sbjct: 64 AGIVWTDKVEEAFKGVDVAFLVGSFPRKDGMDRSDLLAKNGGIFTVQGKALNDYAKPTVK 123
Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172
+LV+ NP N+ IA + K+ + N +T LD R L + KI
Sbjct: 124 VLVVGNPANTNCLIAQASAPKL---QNKNWCAMTRLDHNRMVGALAAKFGVTPEKI---- 176
Query: 173 DKTTMHRKVTVIGGHSGETIIPIITDKS---------LVFQLDKQY--EHFIHRVQFGGD 221
KV + G HS T +P T + + +L K+Y F + G
Sbjct: 177 ------HKVCIWGNHS-NTQVPDTTHATVDLPEGTVKVADKLPKEYLEGEFAQMIATRGG 229
Query: 222 EIVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLV 281
++K + + A + A A ++ + E + +S + +P +
Sbjct: 230 AVIKMRGAS------SAASAANAALTCVKDWLYGTAEGDFVSMAIPVPDN-------EPY 276
Query: 282 GDNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFI 337
G FS P+ + V + + +L+ + + KEL E +
Sbjct: 277 GIKQGTIFSFPVTVSKDGEVHVVEGL--ELNDWVKGRLEATEKELIGEKETAWKVL 330
>2X0J-A nrPDB
Length = 294
Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats.
Identities = 80/336 (23%), Positives = 137/336 (40%), Gaps = 48/336 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTN-SSCVGYD 58
+K+ +GA G VG + L+ V E+AL DI A G DL+H
Sbjct: 1 MKLGFVGA-GRVGSTSAFTCLLNLDVDEIALVDIAEDLAVGEAMDLAHAAAGIDKYPKIV 59
Query: 59 KDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
+ + L ++++++ AG+ RKPG+TR DL NAGI+K + + + AP ++ILV++N
Sbjct: 60 GGADYSLLKGSEIIVVTAGLARKPGMTRLDLAHKNAGIIKDIAKKIVENAPESKILVVTN 119
Query: 119 PVNSLVPIAVETLKKMGKFKPGNVMGVTN-LDLVRAETFLVDYLMLKNPKIGQEQDKTTM 177
P++ + I K V G+ N LD R + L +
Sbjct: 120 PMDVMTYIM----WKESGKPRNEVFGMGNQLDSQRLKERLYNA-------------GARN 162
Query: 178 HRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSM 237
R+ +IG H G+++ + F + +E + V+F E++K K G+
Sbjct: 163 IRRAWIIGEH-GDSM--FVAKSLADFDGEVDWEAVENDVRFVAAEVIKRK---GATIFGP 216
Query: 238 AFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRN 297
A A + + V+ E + + L G + +P L
Sbjct: 217 AVAIYRMVKAVVEDT------GEIIPTSMILQGEYGIENVA----------VGVPAKLGK 260
Query: 298 GSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKG 333
D KLS E + + + K LR+ +E+
Sbjct: 261 NGAEVADI----KLSDEEIEKLRNSAKILRERLEEL 292
>4KDE-A nrPDB
Length = 341
Score = 183 bits (463), Expect = 1e-46, Method: Composition-based stats.
Identities = 79/354 (22%), Positives = 141/354 (39%), Gaps = 49/354 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDI----RAAEGIGKDLSHINTNS 52
V+VA+ GA+G +G L + + + L L +I +A EG+ +L
Sbjct: 5 VRVAVTGAAGQIGYSLLFRIAAGEMLGKDQPVILQLLEIPQAMKALEGVVMELEDCAFPL 64
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNA 111
D + +A L+ PRK G+ R DL ++N I A+ + A +
Sbjct: 65 LAGLEATDDPKVAFKDADYALLVGAAPRKAGMERRDLLQVNGKIFTEQGRALAEVAKKDV 124
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171
++LV+ NP N+ IA K P N +T LD RA+ L +I
Sbjct: 125 KVLVVGNPANTNALIAY---KNAPGLNPRNFTAMTRLDHNRAKAQLAKKTGTGVDRI--- 178
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQL-----DKQYEH--FIHRVQFGGDEIV 224
R++TV G HS T+ P + + + D ++ FI V G I+
Sbjct: 179 -------RRMTVWGNHS-STMFPDLFHAEVDGRPALELVDMEWYEKVFIPTVAQRGAAII 230
Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284
+A+ + A + A A E +R + PE + +S V G +
Sbjct: 231 QARGAS------SAASAANAAIEHIRDWALGTPEGDWVSMAVPSQGEYGIPEGIV----- 279
Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338
+S P+ ++G+ ++ + + + + ++ +EL +E+ K+ L
Sbjct: 280 ----YSFPVTAKDGAYRVVEGLEINEFARKRMEI---TAQELLDEMEQVKALGL 326
>7MDH-A nrPDB
Length = 375
Score = 179 bits (453), Expect = 2e-45, Method: Composition-based stats.
Identities = 77/345 (22%), Positives = 123/345 (35%), Gaps = 52/345 (15%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSE-----LALY----DIRAAEGIGKDLSHINTN 51
+V +A+ GA+G + L L + L L +A EG+ +L
Sbjct: 32 LVNIAVSGAAGMISNHLLFKLASGEVFGQDQPIALKLLGSERSFQALEGVAMELEDSLYP 91
Query: 52 SSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PN 110
+ L+ PR PG+ R L +N I A+ A N
Sbjct: 92 LLREVSIGIDPYEVFEDVDWALLIGAKPRGPGMERAALLDINGQIFADQGKALNAVASKN 151
Query: 111 ARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQ 170
++LV+ NP N+ I LK N +T LD RA+ L K G
Sbjct: 152 VKVLVVGNPCNTNALI---CLKNAPDIPAKNFHALTRLDENRAKCQLA-------LKAGV 201
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITD--------KSLVFQLDKQYEHFIHRVQFGGDE 222
DK + VT+ G HS T +P + K ++ + E F VQ G
Sbjct: 202 FYDKVS---NVTIWGNHS-TTQVPDFLNAKIDGRPVKEVIKRTKWLEEEFTITVQKRGGA 257
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
+++ + +A+ +++ A A ++S PE + S VY G G
Sbjct: 258 LIQKWGRSSAASTAVSIADA------IKSLVTPTPEGDWFSTGVYTTGNPYG-------- 303
Query: 283 DNSIEYFSLPIVLRNGS------VVSIDTSVLEKLSPREEQLVNT 321
FS+P + VS D + E++ E +L+
Sbjct: 304 IAEDIVFSMPCRSKGDGDYELATDVSNDDFLWERIKKSEAELLAE 348
>1CIV-A nrPDB
Length = 385
Score = 177 bits (448), Expect = 6e-45, Method: Composition-based stats.
Identities = 78/345 (22%), Positives = 124/345 (35%), Gaps = 52/345 (15%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVS-----ELALY----DIRAAEGIGKDLSHINTN 51
++ VA+ GA+G + L L L L A EG+ +L
Sbjct: 42 IINVAVSGAAGMISNHLLFKLASGEVFGPDQPISLKLLGSERSFAALEGVAMELEDSLYP 101
Query: 52 SSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PN 110
+A+ L+ PR PG+ R DL +N I A+ A PN
Sbjct: 102 LLRQVSIGIDPYEIFQDAEWALLIGAKPRGPGMERADLLDINGQIFAEQGKALNAVASPN 161
Query: 111 ARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQ 170
+++V+ NP N+ I LK P N +T LD RA+ L K G
Sbjct: 162 VKVMVVGNPCNTNALI---CLKNAPNIPPKNFHALTRLDENRAKCQLA-------LKAGV 211
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKS--------LVFQLDKQYEHFIHRVQFGGDE 222
DK + VT+ G HS T +P + ++ + F + VQ G
Sbjct: 212 FYDKVS---NVTIWGNHS-TTQVPDFLNAKIHGIPVTEVIRDRKWLEDEFTNMVQTRGGV 267
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
++K + +A+ +++ A +RS PE + S VY G G
Sbjct: 268 LIKKWGRSSAASTAVSIVDA------IRSLVTPTPEGDWFSTGVYTNGNPYG-------- 313
Query: 283 DNSIEYFSLPIVLRNGS------VVSIDTSVLEKLSPREEQLVNT 321
FS+P + V D + +K+ E++L+
Sbjct: 314 IAEDIVFSMPCRSKGDGDYEFVKDVIFDDYLSKKIKKSEDELLAE 358
>4BGU-A nrPDB
Length = 303
Score = 174 bits (441), Expect = 5e-44, Method: Composition-based stats.
Identities = 77/339 (22%), Positives = 129/339 (38%), Gaps = 48/339 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE----GIGKDLSHINTNSSCVGY 57
KV+++GA+G VG L L EL DI E G D +H S
Sbjct: 1 TKVSVIGAAGTVGAAAGYNLALRDVCDELVFVDIPKMEDKTVGQAADTNHGIAYDSNTVV 60
Query: 58 DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVIS 117
+ E+T + + VV+I AG+PR+PG TR DL NA I+ + +++ ++ + + S
Sbjct: 61 TQGGYEDT-AGSDVVVITAGIPRQPGQTRIDLAGDNAPIMDDIGSSLAEYNDDFVSITTS 119
Query: 118 NPVNSLVPIAVETLKKMGKFKPGNVMG-VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
NPV+ L L + G V+G LD R L D
Sbjct: 120 NPVDLLN----RHLYETGDRDRHKVIGFGGRLDSARFRYVLSQRF-----------DVPV 164
Query: 177 MHRKVTVIGGHSGETIIPIITDKSL----VFQLDKQYEHFIHRVQFGGDEIVKAKQGAGS 232
+ T++G H G+ +P+ + + + E + +Q ++++ K G+
Sbjct: 165 KNVDATILGEH-GDAQVPVFSKVRVDGNDPAFSADEKEEILGDLQESAMDVIERK---GA 220
Query: 233 ATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLP 292
A A E VL E L + L G + F +P
Sbjct: 221 TQWGPATGVAHMVEAVLHDT------GEVLPGSLVLDGEFGYEDTA----------FGVP 264
Query: 293 IVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331
+ L + + + L E L++ A ++LR +
Sbjct: 265 VKLGSNGIEEVVEW---DLDDYEADLMDDAAEKLRDQYD 300
>4JCO-A nrPDB
Length = 304
Score = 170 bits (431), Expect = 6e-43, Method: Composition-based stats.
Identities = 72/323 (22%), Positives = 122/323 (37%), Gaps = 48/323 (14%)
Query: 19 LLLKLSPYVSELALYDIRAAE----GIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLI 74
+ L E+ DI E G D +H S + E+T + + VV+I
Sbjct: 19 YNIALRDIADEVVFVDIPDKEDDTVGQAADTNHGIAYDSNTRVRQGGYEDT-AGSDVVVI 77
Query: 75 PAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKM 134
AG+PR+PG TR DL NA I++ + +++ + + L SNPV+ L L +
Sbjct: 78 TAGIPRQPGQTRIDLAGDNAPIMEDIQSSLDEHNDDYISLTTSNPVDLLN----RHLYEA 133
Query: 135 GKFKPGNVMG-VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETII 193
G V+G LD R L + D + + T++G H G+ +
Sbjct: 134 GDRSREQVIGFGGRLDSARFRYVLSEEF-----------DAPVQNVEGTILGEH-GDAQV 181
Query: 194 PIITDKSLVFQLDK----QYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAEEVL 249
P+ + + + + E + +Q ++++ K G+ A A E +L
Sbjct: 182 PVFSKVRVDGTDPEFSGDEKEQLLGDLQESAMDVIERK---GATEWGPARGVAHMVEAIL 238
Query: 250 RSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVSIDTSVLE 309
E L A V L G + F +P+ L + V I
Sbjct: 239 HDT------GEVLPASVKLEGEFGHEDTA----------FGVPVRLGSNGVEEIVEW--- 279
Query: 310 KLSPREEQLVNTAVKELRKNIEK 332
L E+ L+ A ++L +K
Sbjct: 280 DLDDYEQDLMADAAEKLSDQYDK 302
>4UUM-A nrPDB
Length = 341
Score = 162 bits (410), Expect = 2e-40, Method: Composition-based stats.
Identities = 67/342 (19%), Positives = 123/342 (35%), Gaps = 48/342 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSE----LALYDIRAAE----GIGKDLSHINTNSSC 54
V I GA+G +G LS + + L L DI A + +L
Sbjct: 6 HVLITGAAGQIGYILSHWIASGELYGDRQVYLHLLDIPPAMNRLTALTMELEDCAFPHLA 65
Query: 55 VGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA-PNARI 113
+ + + A +P KPG R DL N+ I K+ + K+A P+ ++
Sbjct: 66 GFVATTDPKAAFKDIDCAFLVASMPLKPGQVRADLISSNSVIFKNTGEYLSKWAKPSVKV 125
Query: 114 LVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQD 173
LVI NP N+ IA+ K + KP N ++ LD RA + L + +
Sbjct: 126 LVIGNPDNTNCEIAMLHAKNL---KPENFSSLSMLDQNRAYYEVASKLGVDVKDV----- 177
Query: 174 KTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQ-----------YEHFIHRVQFGGDE 222
+ V G H GE+++ +T + + Q ++ F ++ +
Sbjct: 178 -----HDIIVWGNH-GESMVADLTQATFTKEGKTQKVVDVLDHDYVFDTFFKKIGHRAWD 231
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
I++ + +A + K A + ++++ E LS + +P G
Sbjct: 232 ILEHRGFTSAA------SPTKAAIQHMKAWLFGTAPGEVLSMGIPVP-------EGNPYG 278
Query: 283 DNSIEYFSLPI-VLRNGSVVSIDTSVLEKLSPREEQLVNTAV 323
FS P V + G + ++ + + +
Sbjct: 279 IKPGVVFSFPCNVDKEGKIHVVEGFKVNDWLREKLDFTEKDL 320
>3D5T-A nrPDB
Length = 331
Score = 160 bits (405), Expect = 6e-40, Method: Composition-based stats.
Identities = 70/351 (19%), Positives = 122/351 (34%), Gaps = 48/351 (13%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDIRAAE----GIGKDLSHINTNSS 53
+VA+ GA+G + L + + + L L D+ A+ G+ +L
Sbjct: 11 RVAVTGAAGQIAYSLLFRIANGDLLGKDQPVILQLLDLPQAQAAVKGVVMELDDCAFPLL 70
Query: 54 CVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP-NAR 112
D + +A V L+ PR G+ R DL NA I A+ + A + +
Sbjct: 71 AGVVITDDPKVAFKDADVALLVGARPRSKGMERKDLLSANAEIFTVQGAALNEVASRDVK 130
Query: 113 ILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQ 172
+LV+ NP N+ IA+ K N + LD RA + L I
Sbjct: 131 VLVVGNPANTNAYIAM---KSAPDLPKKNFTAMLRLDHNRALSQLAAKSGKPVASI---- 183
Query: 173 DKTTMHRKVTVIGGHSGETIIPII--------TDKSLVFQLDKQYEHFIHRVQFGGDEIV 224
K+ V G HS T+ P + L+ + FI V G I+
Sbjct: 184 ------EKLAVWGNHS-PTMYPDFRFATAEGESLLKLINDDVWNRDTFIPTVGKRGAAII 236
Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284
+A+ LS A + A A + +R + + ++ + G G
Sbjct: 237 EARG------LSSAASAANAAIDHVRDWVLGTN-GKWVTMGIPSDGSY---------GIP 280
Query: 285 SIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335
+ +P++ NG ++ ++ S + + E R +
Sbjct: 281 EDIIYGVPVICENGEYKRVEGLEIDAFSREKMDGTLAELLEERDGVAHLLK 331
>4TVO-A nrPDB
Length = 330
Score = 153 bits (386), Expect = 1e-37, Method: Composition-based stats.
Identities = 69/355 (19%), Positives = 117/355 (32%), Gaps = 50/355 (14%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVS-----ELALYDIR----AAEGIGKDLSHINTNS 52
+KVA+ GA+G +G L L + EL L +I A EG+ +L
Sbjct: 6 LKVAVTGAAGQIGYSLLFRLASGSLLGPDRPIELRLLEIEPALQALEGVVMELDDCAFPL 65
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKF-APNA 111
+ + L+ PR G+ R DL + N I + A+ A +
Sbjct: 66 LSGVEIGSDPQKIFDGVSLALLVGARPRGAGMERSDLLEANGAIFTAQGKALNAVAADDV 125
Query: 112 RILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQE 171
R+ V NP N+ IA+ +T LD RA + L I
Sbjct: 126 RVGVTGNPANTNALIAMT---NAPDIPRERFSALTRLDHNRAISQLAAKTGAAVTDI--- 179
Query: 172 QDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQY--------EHFIHRVQFGGDEI 223
+K+T+ G HS T P + + + + + FI V G I
Sbjct: 180 -------KKMTIWGNHS-ATQYPDLFHAEVAGKNAAEVVNDQAWIEDEFIPTVAKRGAAI 231
Query: 224 VKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGD 283
+ A+ + A + A + R + P + +S V G +
Sbjct: 232 IDARGAS------SAASAASATIDAARDWLLGTPADDWVSMAVVSDGSYGVPEGLIS--- 282
Query: 284 NSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFIL 338
S P+ + G+ + +++ S ++ + EL L
Sbjct: 283 ------SFPVTTKGGNWTIVSGLEIDEFS---RGRIDKSTAELADERSAVTELGL 328
>3DL2-A nrPDB
Length = 303
Score = 153 bits (385), Expect = 1e-37, Method: Composition-based stats.
Identities = 67/335 (20%), Positives = 135/335 (40%), Gaps = 52/335 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAA-EGIGKDLSHINTNSSCVGYDKDS 61
K+ ++G G +G +L + L L D+ +G DL N + + D
Sbjct: 16 KITVVGG-GELGIACTLAISAKGIADRLVLLDLSEGTKGATMDLEIFNLPNVEISKD--- 71
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVN 121
+ ++++VV+ + D+ + N + ++LV A+G ++ ++ +LV S PV
Sbjct: 72 -LSASAHSKVVIFTVN-SLGSSQSYLDVVQSNVDMFRALVPALGHYSQHSVLLVASQPVE 129
Query: 122 SLVPIAVETLKKMGKFKPGNVMGV-TNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
+ + K+ F V+G+ NLD R + + + L + ++
Sbjct: 130 IMTYVT----WKLSTFPANRVIGIGCNLDSQRLQYIITNVLKAQTS-----------GKE 174
Query: 181 VTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQ--FGGDEIVKAKQGAGSATLSMA 238
V VIG + K L + ++ +VQ E+++ K G + S+
Sbjct: 175 VWVIGEQGED--------KVLTWSGQEEVVSHTSQVQLSNRAMELLRVK---GQRSWSVG 223
Query: 239 FAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLR-N 297
+ A + ++ N K + S+SA A+ NS + SLP +L N
Sbjct: 224 LSVADMVDSIV----NNKKKVHSVSAL-----------AKGYYDINSEVFLSLPCILGTN 268
Query: 298 GSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEK 332
G I T++ E + Q +++ L++ ++
Sbjct: 269 GVSEVIKTTLKEDTVTEKLQSSASSIHSLQQQLKL 303
>1B8U-A nrPDB
Length = 329
Score = 152 bits (383), Expect = 2e-37, Method: Composition-based stats.
Identities = 64/349 (18%), Positives = 117/349 (33%), Gaps = 48/349 (13%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSE-----LALYDI------RAAEGIGKDLSHINT 50
++VA+ GA+G + L + + + L L +I +A +G+ ++
Sbjct: 6 MRVAVTGAAGQICYSLLFRIANGDMLGKDQPVILQLLEIPNEKAQKALQGVMMEIDDCAF 65
Query: 51 NSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAP- 109
+A V L+ PR PG+ R DL + NA I A+ A
Sbjct: 66 PLLAGMTAHADPMTAFKDADVALLVGARPRGPGMERKDLLEANAQIFTVQGKAIDAVASR 125
Query: 110 NARILVISNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIG 169
N ++LV+ NP N+ IA+ K N + LD RA + + I
Sbjct: 126 NIKVLVVGNPANTNAYIAM---KSAPSLPAKNFTAMLRLDHNRALSQIAAKTGKPVSSI- 181
Query: 170 QEQDKTTMHRKVTVIGGHSGET-------IIPIITDKSLVFQLDKQYEHFIHRVQFGGDE 222
K+ V G HS I + K ++ + F+ V G
Sbjct: 182 ---------EKLFVWGNHSPTMYADYRYAQIDGASVKDMINDDAWNRDTFLPTVGKRGAA 232
Query: 223 IVKAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVG 282
I+ A+ +S A + A A + + + + + + G +
Sbjct: 233 IIDARG------VSSAASAANAAIDHIHDWVLGTA-GKWTTMGIPSDGSYGIPEG----- 280
Query: 283 DNSIEYFSLPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIE 331
F P+ NG + ++ S + + E + ++
Sbjct: 281 ----VIFGFPVTTENGEYKIVQGLSIDAFSQERINVTLNELLEEQNGVQ 325
>6IHE-A nrPDB
Length = 303
Score = 146 bits (369), Expect = 1e-35, Method: Composition-based stats.
Identities = 62/340 (18%), Positives = 127/340 (37%), Gaps = 47/340 (13%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI--RAAEGIGKDLSHINTNSSCVG-YDK 59
KV +GA G +GQ ++ +S V E +YDI + +L H
Sbjct: 2 KVGFIGA-GKIGQTIAYSALVSGAVDEAVIYDIIPELPDKFEHELRHAFATKGIKANVLG 60
Query: 60 DSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNP 119
+ + +S +V+I AG PRKPG++R DLF NA I+ L + P A L+++NP
Sbjct: 61 TNSLDDVSGMDIVVISAGKPRKPGMSRRDLFVDNAKIMIDLAQKLPSKNPGAIYLMVANP 120
Query: 120 VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHR 179
V+ + + ++ K+ + ++ +R +F+ L + +
Sbjct: 121 VDMMASVFMKYSKQFT------ISAGDQVETMRMRSFIAKKLKIPVTSVDGF-------- 166
Query: 180 KVTVIGGHSGETIIPIITDKSLVFQLDKQY----EHFIHRVQFGGDEIVKAKQGAGSATL 235
+GG GE + + + + + ++ + V+ EI++ G T
Sbjct: 167 ----VGGEHGEDAVVLWSTVKIKGKPVDEFNINKDEVSDYVKKIPGEIIRV---IGGTTW 219
Query: 236 SMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVL 295
A + + S + + I + S P V+
Sbjct: 220 GPGTIIADIIKSIAFSENRVMSIATP------------------KEYEKEIIHVSAPTVV 261
Query: 296 RNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335
+ S+++ + EK + + ++N+++ +
Sbjct: 262 GSSIGPSLESLLDEKDRWHLNSAMKDFYEAYKENLKQLEQ 301
>1HYH-A nrPDB
Length = 309
Score = 126 bits (315), Expect = 2e-29, Method: Composition-based stats.
Identities = 58/345 (16%), Positives = 117/345 (33%), Gaps = 52/345 (15%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGK--DLSHINTNSSCVGYDKD 60
K+ I+G G VG ++ L + D A+ D N G
Sbjct: 3 KIGIIGL-GNVGAAVAHGLIAQGVADDYVFIDANEAKVKADQIDFQDAMANLEAHGNIVI 61
Query: 61 SIENTLSNAQVVLIPAGVPR----KPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ L++A VV+ G + P R K + +V+S+ T + + + ++VI
Sbjct: 62 NDWAALADADVVISTLGNIKLQQDNPTGDRFAELKFTSSMVQSVGTNLKESGFHGVLVVI 121
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMG-VTNLDLVRAETFLVDYL-----MLKNPKIGQ 170
SNPV+ + + + + F V+G T LD R + + + + +G+
Sbjct: 122 SNPVDVITAL----FQHVTGFPAHKVIGTGTLLDTARMQRAVGEAFDLDPRSVSGYNLGE 177
Query: 171 EQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGA 230
+ + + G T L D + GG ++ K
Sbjct: 178 HGNSQFVAWSTVRVMGQPIVT---------LADAGDIDLAAIEEEARKGGFTVLNGK--- 225
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290
G + +A + + A+ V+ H E D+ Y S
Sbjct: 226 GYTSYGVATSAIRIAKAVMADAHAEL--------------------VVSNRRDDMGMYLS 265
Query: 291 LPIVLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKS 335
P ++ V++ T L+ E++ + + +++ ++
Sbjct: 266 YPAIIGRDGVLAETTL---DLTTDEQEKLLQSRDYIQQRFDEIVD 307
>3FEF-A nrPDB
Length = 450
Score = 38.2 bits (87), Expect = 0.005, Method: Composition-based stats.
Identities = 25/158 (15%), Positives = 57/158 (36%), Gaps = 25/158 (15%)
Query: 2 VKVAILGAS--GGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59
+K+A +G G +S L +ALYD+ ++ ++ + Y+
Sbjct: 6 IKIAYIGGGSQGWARSLMSDLSIDERMSGTVALYDLDFEAAQKNEVIGNHSGNGRWRYEA 65
Query: 60 -DSIENTLSNAQVVLIP------------AGVPRKPG--LTRDDLFK--------MNAGI 96
+++ LS A +V+I +P + G + D I
Sbjct: 66 VSTLKKALSAADIVIISILPGSLDDMEVDVHLPERCGIYQSVGDTVGPGGIIRGLRAVPI 125
Query: 97 VKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKM 134
+ A+ +AP + ++ +NP++ + + +
Sbjct: 126 FAEIARAIRDYAPESWVINYTNPMSVCTRVLYKVFPGI 163
>3PLN-A nrPDB
Length = 424
Score = 37.4 bits (85), Expect = 0.008, Method: Composition-based stats.
Identities = 24/126 (19%), Positives = 45/126 (35%), Gaps = 19/126 (15%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG----------IGKDLSHINTN 51
+K+ I G +G VG +L+ + E+ DI A+ + K++
Sbjct: 37 MKITISG-TGYVGLSNGVLIAQN---HEVVALDIVQAKVDMLNQKISPIVDKEIQEYLAE 92
Query: 52 SSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA 111
+ NA V+I P N V++++ V + PNA
Sbjct: 93 KPLNFRATTDKHDAYRNADYVIIATPTDYDPKTN-----YFNTSTVEAVIRDVTEINPNA 147
Query: 112 RILVIS 117
+++ S
Sbjct: 148 VMIIKS 153
>4XRR-A nrPDB
Length = 456
Score = 35.5 bits (80), Expect = 0.032, Method: Composition-based stats.
Identities = 25/110 (22%), Positives = 37/110 (33%), Gaps = 20/110 (18%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK-- 59
+KV I GA G VG L++ L +E+ D + G DL G
Sbjct: 16 LKVVIAGA-GYVGTCLAVTLAGRG--AEVVAVD--SDPGTVADLRAGRCRLPEPGLAGAV 70
Query: 60 -----------DSIENTLSNAQVVLIPAGVPRKPG--LTRDDLFKMNAGI 96
+ + + A VV++ G P G + D L I
Sbjct: 71 RDLAATGRLTASTSYDPVGAADVVIVTVGTPTDAGHEMVTDQLVAACEQI 120
>1HE4-A nrPDB
Length = 206
Score = 35.1 bits (79), Expect = 0.039, Method: Composition-based stats.
Identities = 32/183 (17%), Positives = 59/183 (32%), Gaps = 24/183 (13%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K+AI GA+G G + Y + + D G +H+ D +
Sbjct: 5 KIAIFGATGQTGLTTLAQAVQAGYEVTVLVRDSSRLPSEGPRPAHVVVGDVLQAAD---V 61
Query: 63 ENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNA--GIVKSLVTAVGKFAPNARILVISNPV 120
+ T++ V++ G TR+DL +++V A+ + + S
Sbjct: 62 DKTVAGQDAVIVLLG-------TRNDLSPTTVMSEGARNIVAAMKAHGVDKVVACTS--- 111
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
L K P + VT+ D +R L + + + +
Sbjct: 112 -------AFLLWDPTKVPP-RLQAVTD-DHIRMHKVLRESGLKYVAVMPPHIGDQPLTGA 162
Query: 181 VTV 183
TV
Sbjct: 163 YTV 165
>3WMX-A nrPDB
Length = 358
Score = 34.4 bits (77), Expect = 0.081, Method: Composition-based stats.
Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 1/54 (1%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVG 56
K+ I+GA+G +G L+L L + + D+ G L+H N++ G
Sbjct: 27 KILIVGANGQIGSELALALAERYGRTNVITSDVVPT-GRHVHLTHEMLNATDRG 79
>5K0S-A nrPDB
Length = 536
Score = 34.0 bits (76), Expect = 0.092, Method: Composition-based stats.
Identities = 13/75 (17%), Positives = 23/75 (30%), Gaps = 9/75 (12%)
Query: 47 HINTNSSCVGYDKDSIENTLSNAQVVLIPA----GV-----PRKPGLTRDDLFKMNAGIV 97
HI + D + L+ V + G+ RK G+T DL N
Sbjct: 41 HIGHAYELIATDAMARFQRLNGMDVYFLTGTDEHGIKMLQSARKEGITPRDLADRNTSAF 100
Query: 98 KSLVTAVGKFAPNAR 112
+ + + +
Sbjct: 101 RRMAEVLNSSNDDYI 115
>3GRP-A nrPDB
Length = 266
Score = 34.0 bits (76), Expect = 0.092, Method: Composition-based stats.
Identities = 29/157 (18%), Positives = 51/157 (32%), Gaps = 23/157 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K + GA+GG+G+ ++ + L + I DL S D+ SI
Sbjct: 29 KALVTGATGGIGEAIARCFHAQGAIVGLHGTREDKLKEIAADLGKDVFVFSANLSDRKSI 88
Query: 63 -------ENTLSNAQVVLIPAGVPRKPGLTR------DDLFKMNAGIVKSLVTAVGKF-- 107
E + +++ AG+ R R DD+ +N +L +
Sbjct: 89 KQLAEVAEREMEGIDILVNNAGITRDGLFVRMQDQDWDDVLAVNLTAASTLTRELIHSMM 148
Query: 108 --------APNARILVISNPVNSLVPIAVETLKKMGK 136
+ + V+ NP + A L K
Sbjct: 149 RRRYGRIINITSIVGVVGNPGQTNYCAAKAGLIGFSK 185
>3WYE-A nrPDB
Length = 256
Score = 33.2 bits (74), Expect = 0.18, Method: Composition-based stats.
Identities = 18/94 (19%), Positives = 41/94 (43%), Gaps = 12/94 (12%)
Query: 1 MVKVAILGASGG-VGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59
M KVA++ +G +G+ ++L L + +A Y+ A+ + +++ ++ V D
Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60
Query: 60 DSIENTLS----------NAQVVLIPAGVPR-KP 82
+ + V++ AG+ + KP
Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGIAQIKP 94
>1ORR-A nrPDB
Length = 347
Score = 32.8 bits (73), Expect = 0.21, Method: Composition-based stats.
Identities = 24/128 (18%), Positives = 47/128 (36%), Gaps = 21/128 (16%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLS-----------HIN 49
M K+ I G G +G L+ +L ++D + +G +L H +
Sbjct: 1 MAKLLITGGCGFLGSNLASFALSQGI--DLIVFDNLSRKGATDNLHWLSSLGNFEFVHGD 58
Query: 50 TNSSCVGY---DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGK 106
+ K ++ A V + + P + F++N G +L+ AV +
Sbjct: 59 IRNKNDVTRLITKYMPDSCFHLAGQVAMTTSID-NPCMD----FEINVGGTLNLLEAVRQ 113
Query: 107 FAPNARIL 114
+ N I+
Sbjct: 114 YNSNCNII 121
>4F3Y-A nrPDB
Length = 272
Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats.
Identities = 17/72 (23%), Positives = 32/72 (44%), Gaps = 1/72 (1%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+K+AI GASG +G+ L + +P + + D + +G+D + D
Sbjct: 8 MKIAIAGASGRMGRMLIEAVLAAPDATLVGALDRTGSPQLGQD-AGAFLGKQTGVALTDD 66
Query: 62 IENTLSNAQVVL 73
IE + A ++
Sbjct: 67 IERVCAEADYLI 78
>5C3M-A nrPDB
Length = 447
Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats.
Identities = 26/196 (13%), Positives = 57/196 (29%), Gaps = 37/196 (18%)
Query: 27 VSELALYDIRAAEGIGKDLSHIN------TNSSCVGYDKDSIENTLSNAQVV---LIPAG 77
V EL L DI + + + + + L A V G
Sbjct: 33 VGELWLVDIPEGKEKLEIVGALAKRMVEKAGVPIEIHLTLDRRRALEGADFVTTQFRVGG 92
Query: 78 VPRKPGLTRDDL------FKMN-----------AGIVKSLVTAVGKFAPNARILVISNPV 120
+ + R L + N ++ ++ + + P+A ++ +NP
Sbjct: 93 LEARAKDERIPLKYGVIGQETNGPGGLFKGLRTIPVILDIIRDMEELCPDAWLINFTNPA 152
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRK 180
+ + K+ V+G+ N+ + + L + ++ D
Sbjct: 153 GMVTEAVLRYTKQ------EKVVGLCNVPIGM-RMGVAKLLGVDADRV--HID--FAGLN 201
Query: 181 VTVIGGHSGETIIPII 196
V G H + +
Sbjct: 202 HMVFGLHVYLDGVEVT 217
>4NBV-A nrPDB
Length = 246
Score = 32.4 bits (72), Expect = 0.26, Method: Composition-based stats.
Identities = 23/98 (23%), Positives = 37/98 (37%), Gaps = 9/98 (9%)
Query: 3 KVAIL-GASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+VAI+ GA+ G+G + + + L D++ A T ++ Y D
Sbjct: 6 RVAIITGAAAGIGFATAQRFAEDGAI--VVLCDVQEARVREAAARLAATGATVSAYRVDV 63
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKS 99
+A V + A R D+ NAGI K
Sbjct: 64 TRRDEVDAMVAAVLAA------HQRVDILVNNAGITKD 95
>2EW8-A nrPDB
Length = 249
Score = 32.4 bits (72), Expect = 0.27, Method: Composition-based stats.
Identities = 18/96 (18%), Positives = 40/96 (41%), Gaps = 11/96 (11%)
Query: 3 KVAIL-GASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
K+A++ G + G+G+ ++ + +++A+ D+ A + ++ V D
Sbjct: 8 KLAVITGGANGIGRAIAERFAVEG--ADIAIADLVPAPEAEAAIRNLGRRVLTVKCDVSQ 65
Query: 62 IENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIV 97
+ + + V+ G R D+ NAGI
Sbjct: 66 PGDVEAFGKQVISTFG--------RCDILVNNAGIY 93
>5ZF1-A nrPDB
Length = 301
Score = 31.7 bits (70), Expect = 0.51, Method: Composition-based stats.
Identities = 25/96 (26%), Positives = 40/96 (41%), Gaps = 28/96 (29%)
Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKD----LSHINTNSSCVGYDKD 60
++G S VG P++++L D R G+G D + H T KD
Sbjct: 162 VVIGRSKNVGMPIAMMLHS----------DKRHESGLGMDATVTICHRYTP-------KD 204
Query: 61 SIENTLSNAQVVLIPAGVPR-------KPGLTRDDL 89
+E NA +++ G+P+ KPG T D+
Sbjct: 205 KLEAYCRNADIIITATGLPKLIKADMVKPGATIIDV 240
>1GEG-A nrPDB
Length = 256
Score = 31.3 bits (69), Expect = 0.63, Method: Composition-based stats.
Identities = 17/90 (18%), Positives = 38/90 (42%), Gaps = 11/90 (12%)
Query: 1 MVKVAILGASGG-VGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59
M KVA++ +G +G+ ++L L + +A Y+ A+ + +++ ++ V D
Sbjct: 1 MKKVALVTGAGQGIGKAIALRLVKDGFAVAIADYNDATAKAVASEINQAGGHAVAVKVDV 60
Query: 60 DSIENTLS----------NAQVVLIPAGVP 79
+ + V++ AGV
Sbjct: 61 SDRDQVFAAVEQARKTLGGFDVIVNNAGVA 90
>2BE7-D nrPDB
Length = 153
Score = 31.3 bits (69), Expect = 0.66, Method: Composition-based stats.
Identities = 22/75 (29%), Positives = 30/75 (40%), Gaps = 5/75 (6%)
Query: 45 LSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKM-NAGIVKSLVTA 103
+ HI + S+ +T V +P K G DL K+ N I KS
Sbjct: 17 IDHIPSGQGVKILKLFSLTDTKQRVTVGF---NLPTKDG-NAKDLIKVENTEITKSQANQ 72
Query: 104 VGKFAPNARILVISN 118
+ APNA I +I N
Sbjct: 73 LALLAPNATINIIEN 87
>1BXK-A nrPDB
Length = 355
Score = 30.9 bits (68), Expect = 0.73, Method: Composition-based stats.
Identities = 10/46 (21%), Positives = 17/46 (36%), Gaps = 1/46 (2%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLS 46
M K+ I G +G +G L + + + D G L+
Sbjct: 1 MRKILITGGAGFIGSALVRYIIN-ETSDAVVVVDKLTYAGNLMSLA 45
>5UYY-A nrPDB
Length = 381
Score = 30.9 bits (68), Expect = 0.76, Method: Composition-based stats.
Identities = 14/68 (20%), Positives = 26/68 (38%), Gaps = 13/68 (19%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGI-----------GKDLSHINTN 51
KV ++G +G +G L+L +K + + YDI + DL H
Sbjct: 19 KVVLIG-TGLIGGSLALAIK-KDHDVTITGYDIFQEQVERAKELHVVDEIAVDLQHACEE 76
Query: 52 SSCVGYDK 59
+ + +
Sbjct: 77 AHLIVFAS 84
>1KEU-A nrPDB
Length = 361
Score = 30.9 bits (68), Expect = 0.77, Method: Composition-based stats.
Identities = 10/51 (19%), Positives = 21/51 (41%), Gaps = 1/51 (1%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNS 52
+K+ I G +G +G + + + D G + LS I+ ++
Sbjct: 1 MKILITGGAGFIGSAVV-RHIIKNTQDTVVNIDKLTYAGNLESLSDISESN 50
>5EES-A nrPDB
Length = 247
Score = 30.9 bits (68), Expect = 0.85, Method: Composition-based stats.
Identities = 20/72 (27%), Positives = 32/72 (44%), Gaps = 6/72 (8%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+KV +LGA G VGQ + + +L L A G+ DLS + N + V D +
Sbjct: 2 IKVGVLGAKGRVGQTI---VAAVNESDDLELV---AEIGVDDDLSLLVDNGAEVVVDFTT 55
Query: 62 IENTLSNAQVVL 73
+ N + +
Sbjct: 56 PNAVMGNLEFCI 67
>2GFQ-A nrPDB
Length = 298
Score = 30.9 bits (68), Expect = 0.89, Method: Composition-based stats.
Identities = 23/178 (12%), Positives = 51/178 (28%), Gaps = 44/178 (24%)
Query: 177 MHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLS 236
+ V H G T + + + + ++++ + EI+
Sbjct: 152 LGWTVCYEATHHGPTELEVPSFFIEIGSSEEEW------INDRAGEII------------ 193
Query: 237 MAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEY------FS 290
AE ++ N + + + G K + + + + ++
Sbjct: 194 --------AETIIYVLDNYEKGRSKFKVALGIGGGHYAPKQTKRALEGDLAFGHILPKYA 245
Query: 291 LPI-------VLRNGSVVSIDTSVLEKLSPREEQLVNTAVKELRKNIEKGKSFILDSS 341
P+ L V K S E + + ++ + E G FI D S
Sbjct: 246 QPVSRDVMIKALNRFGEKVEAIYVDWKGSRGETRQLAKSLAQ-----ELGLEFIKDGS 298
>2CVO-A nrPDB
Length = 366
Score = 30.5 bits (67), Expect = 0.96, Method: Composition-based stats.
Identities = 20/75 (26%), Positives = 27/75 (36%), Gaps = 3/75 (4%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL-YDIRAAEGIGKDLSHINTNSSCVGYDKD 60
V++A+LGASG G + LL P + D +A E G H+ T
Sbjct: 24 VRIAVLGASGYTGAEIVRLLANHPQFRIKVMTADRKAGEQFGSVFPHLITQDLPNLVAVK 83
Query: 61 SIENTLSNAQVVLIP 75
SN V
Sbjct: 84 D--ADFSNVDAVFCC 96
>4WOK-A nrPDB
Length = 336
Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats.
Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 2/31 (6%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYD 34
V ++G +G +G + LL Y +YD
Sbjct: 14 VLVVGGAGFIGSHTAKLLAGQGYAP--VVYD 42
>3WTC-A nrPDB
Length = 262
Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats.
Identities = 18/91 (19%), Positives = 41/91 (45%), Gaps = 15/91 (16%)
Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIR-----AAEGIGKDLSHINTNSSCVGYDK 59
A+ GA+ G+G+ ++L L +++ L D++ + L + ++
Sbjct: 12 AVTGAAQGIGKAIALRLAKDG--ADVILLDVKQDTLAETAKEVEALGRRAVALTADISNR 69
Query: 60 DSIENTLSNA-------QVVLIPAGVPR-KP 82
D +TL++A +++ AG+ + KP
Sbjct: 70 DQFRSTLADAAKTLGGLDIMVNNAGICQVKP 100
>2YV3-A nrPDB
Length = 331
Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats.
Identities = 32/161 (19%), Positives = 60/161 (37%), Gaps = 27/161 (16%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60
++VA++GA+G VG+ + +L+ + +SEL LY + G+ +
Sbjct: 1 MRVAVVGATGAVGREILKVLEARNFPLSELRLYASPRSAGVRLAFRGEEIPV-------E 53
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDD---------LFKMNAGIVKSL--VTAVGKFAP 109
+ +VL AG G++R L N+ + V V
Sbjct: 54 PLPEGPLPVDLVLASAGG----GISRAKALVWAEGGALVVDNSSAWRYEPWVPLVVPEVN 109
Query: 110 NARIL----VISNPVNSLVPIAVETLKKMGKFKPGNVMGVT 146
+I +I+NP + +A+ F+ V+ T
Sbjct: 110 REKIFQHRGIIANPNCTTAILAMALWPLHRAFQAKRVIVAT 150
>2NNL-D nrPDB
Length = 337
Score = 30.5 bits (67), Expect = 1.2, Method: Composition-based stats.
Identities = 15/78 (19%), Positives = 26/78 (33%), Gaps = 5/78 (6%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY-----D 58
V + GASG +G L + L Y + D + + L + + D
Sbjct: 8 VCVTGASGFIGSWLVMRLLERGYTVRATVRDPTNVKKVKHLLDLPKAETHLTLWKADLAD 67
Query: 59 KDSIENTLSNAQVVLIPA 76
+ S + + V A
Sbjct: 68 EGSFDEAIKGCTGVFHVA 85
>4A7P-A nrPDB
Length = 446
Score = 30.1 bits (66), Expect = 1.4, Method: Composition-based stats.
Identities = 30/150 (20%), Positives = 53/150 (35%), Gaps = 23/150 (15%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYD-------------IRAAEGIGKDLSHI 48
V++A++G +G VG S + E+ D + E L
Sbjct: 9 VRIAMIG-TGYVGLVSGACF--SDFGHEVVCVDKDARKIELLHQNVMPIYEPGLDALVAS 65
Query: 49 NTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFA 108
N + + + D E + +A V I G P + G DL + A + + + K
Sbjct: 66 NVKAGRLSFTTDLAEG-VKDADAVFIAVGTPSRRGDGHADLSYVFAA-AREIAENLTK-- 121
Query: 109 PNARILVISNPV---NSLVPIAVETLKKMG 135
P+ + + PV + + I E G
Sbjct: 122 PSVIVTKSTVPVGTGDEVERIIAEVAPNSG 151
>3RFT-A nrPDB
Length = 267
Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats.
Identities = 21/119 (17%), Positives = 44/119 (36%), Gaps = 10/119 (8%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60
M ++ + GA+G +G+ + L P L L D+ + G + C D +
Sbjct: 3 MKRLLVTGAAGQLGRVMRERLA--PMAEILRLADLSPLDPAGPN----EECVQCDLADAN 56
Query: 61 SIENTLSNAQVVLIPAGVP-RKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISN 118
++ ++ ++ G+ KP + + N + +L A + SN
Sbjct: 57 AVNAMVAGCDGIVHLGGISVEKPFE---QILQGNIIGLYNLYEAARAHGQPRIVFASSN 112
>2Q1W-A nrPDB
Length = 333
Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats.
Identities = 18/85 (21%), Positives = 27/85 (31%), Gaps = 5/85 (5%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60
M KV I G G +G ++ LL ++ D A H N
Sbjct: 21 MKKVFITGICGQIGSHIAELLLERG--DKVVGIDNFATGRREHLKDHPNLTFVEGSIADH 78
Query: 61 SIENTLSN---AQVVLIPAGVPRKP 82
++ N L V+ A + P
Sbjct: 79 ALVNQLIGDLQPDAVVHTAASYKDP 103
>1LSS-A nrPDB
Length = 140
Score = 30.1 bits (66), Expect = 1.5, Method: Composition-based stats.
Identities = 17/99 (17%), Positives = 35/99 (35%), Gaps = 7/99 (7%)
Query: 6 ILGASGGVGQPLSLLLKLSPYVSELALYDIRAA--EGIGKDLSHINTNSSCVGYDKDSIE 63
I+ G VG L+ L + ++ L DI + ++ + N C
Sbjct: 8 IIAGIGRVGYTLAKSLSEKGH--DIVLIDIDKDICKKASAEIDALVINGDCTKIKTLEDA 65
Query: 64 NTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVT 102
+ +A + + G ++ L + GI K++
Sbjct: 66 G-IEDADMYIAVTGKEEVNLMS--SLLAKSYGINKTIAR 101
>3G05-A nrPDB
Length = 576
Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats.
Identities = 20/141 (14%), Positives = 46/141 (32%), Gaps = 12/141 (8%)
Query: 87 DDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK--KMGKFKPGNVMG 144
+DL N +V ++ KF A +L + ++ + I ++ + G +
Sbjct: 152 EDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPL-- 209
Query: 145 VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQ 204
R L + K G +V+ G+ +P+ + Q
Sbjct: 210 -----SRRLREL---PLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQ 261
Query: 205 LDKQYEHFIHRVQFGGDEIVK 225
+Q +I ++++
Sbjct: 262 HPQQVPCYITHTNEKTHDVIR 282
>3CP2-A nrPDB
Length = 649
Score = 29.7 bits (65), Expect = 1.9, Method: Composition-based stats.
Identities = 20/141 (14%), Positives = 46/141 (32%), Gaps = 12/141 (8%)
Query: 87 DDLFKMNAGIVKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLK--KMGKFKPGNVMG 144
+DL N +V ++ KF A +L + ++ + I ++ + G +
Sbjct: 146 EDLIVENDRVVGAVTQMGLKFRAKAVVLTVGTFLDGKIHIGLDNYSGGRAGDPPSIPL-- 203
Query: 145 VTNLDLVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQ 204
R L + K G +V+ G+ +P+ + Q
Sbjct: 204 -----SRRLREL---PLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMGNASQ 255
Query: 205 LDKQYEHFIHRVQFGGDEIVK 225
+Q +I ++++
Sbjct: 256 HPQQVPCYITHTNEKTHDVIR 276
>5JW6-A nrPDB
Length = 371
Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats.
Identities = 44/302 (14%), Positives = 95/302 (31%), Gaps = 21/302 (6%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDI---RAAEGIGKDLSHINTNSSCVGYDK 59
K +LGA+G VGQ LLL P++ EL A + + T +
Sbjct: 8 KCGVLGATGSVGQRFILLLADHPFL-ELHAIGASNRSAGKKYKDAVRWKQTTAMSERLSN 66
Query: 60 DSIENTLSN--AQVVLIPAGVPR-KPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ + ++ + L+ +G+ G + K + + + + + ++
Sbjct: 67 LVLRDCRADQFSDCDLVFSGLNSDVAGEIEMEFIKAEIPVF----SNAKNYRKHPLVPLV 122
Query: 117 SNPVNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
VN + +K K G ++ + A +V K G ++
Sbjct: 123 VPTVNPQHLDLIPHQRKEFGLKKGFLVC----NSNCAVIGVVIPFAALQAKFGPVEEVEV 178
Query: 177 MHRKVTVIGGHSGETIIPIITDK-SLVFQLDKQYEHFIHRVQFG----GDEIVKAKQGA- 230
+ G+ G + I+ + + + + E+ ++ + K
Sbjct: 179 FTEQAVSGAGYPGVPSMDIMDNVIPYISGEEDKLENEAQKILGSLNADATAFDEQKGLTV 238
Query: 231 GSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFS 290
G+ + A LR + P E + + + K +I+ F
Sbjct: 239 GATCTRVGVTDGHMAFVSLRFKNRPGPSAEEVKQAMREYQSEAQKLGCPSAPREAIKVFD 298
Query: 291 LP 292
P
Sbjct: 299 EP 300
>5ITV-A nrPDB
Length = 255
Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats.
Identities = 18/93 (19%), Positives = 27/93 (29%), Gaps = 10/93 (10%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIE 63
V I G + G+G + + + DI A+G N V D
Sbjct: 10 VLITGGASGIGYAAVQAFLGQQ--ANVVVADIDEAQGEAMVRKENNDRLHFVQTDITDEA 67
Query: 64 NTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGI 96
+ + G D+ NAGI
Sbjct: 68 ACQHAVESAVHTFGG--------LDVLINNAGI 92
>4B4O-A nrPDB
Length = 298
Score = 29.7 bits (65), Expect = 2.1, Method: Composition-based stats.
Identities = 10/39 (25%), Positives = 19/39 (48%), Gaps = 2/39 (5%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG 40
++V + G +G +G L+ LL + E+ L + G
Sbjct: 1 MRVLVGGGTGFIGTALTQLLNARGH--EVTLVSRKPGPG 37
>1E3W-A nrPDB
Length = 261
Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats.
Identities = 14/84 (16%), Positives = 28/84 (33%), Gaps = 11/84 (13%)
Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHIN--TNSSCVGYDKDSI 62
I G + G+G + L + L D+ +EG + + + +
Sbjct: 14 VITGGASGLGLSTAKRLVGQGATA--VLLDVPNSEGETEAKKLGGNCIFAPANVTSEKEV 71
Query: 63 ENTLSNA-------QVVLIPAGVP 79
+ L+ A V + AG+
Sbjct: 72 QAALTLAKEKFGRIDVAVNCAGIA 95
>5TEK-A nrPDB
Length = 250
Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats.
Identities = 9/31 (29%), Positives = 15/31 (48%), Gaps = 3/31 (9%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELAL 32
++V +LGA G VG + + +L L
Sbjct: 6 MRVGVLGAKGKVGATMVRAVA---AADDLTL 33
>2FV8-A nrPDB
Length = 207
Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats.
Identities = 22/127 (17%), Positives = 45/127 (35%), Gaps = 19/127 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K+ ++G G G+ L++ E+ + + E D+ +D
Sbjct: 27 KLVVVG-DGACGKTCLLIVFSKDEFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 83
Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115
E+ + + V+L+ V D + I + V V F PN I++
Sbjct: 84 EDYDRLRPLSYPDTDVILMCFSV------DSPDSLE---NIPEKWVPEVKHFCPNVPIIL 134
Query: 116 ISNPVNS 122
++N +
Sbjct: 135 VANKKDL 141
>3PWZ-A nrPDB
Length = 272
Score = 29.4 bits (64), Expect = 2.6, Method: Composition-based stats.
Identities = 22/82 (26%), Positives = 34/82 (41%), Gaps = 4/82 (4%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALY--DIRAAEGIGKDLSHINTNSSCVGYDKD 60
+V +LGA G V +LL L SEL + D+ A + +L H S +
Sbjct: 122 RVLLLGAGGAVRG--ALLPFLQAGPSELVIANRDMAKALALRNELDHSRLRISRYEALEG 179
Query: 61 SIENTLSNAQVVLIPAGVPRKP 82
+ + NA + A +P P
Sbjct: 180 QSFDIVVNATSASLTADLPPLP 201
>3RSH-A nrPDB
Length = 251
Score = 29.4 bits (64), Expect = 2.7, Method: Composition-based stats.
Identities = 24/100 (24%), Positives = 38/100 (38%), Gaps = 18/100 (18%)
Query: 3 KVA-ILGASGGVGQPLSLLLKLSP---------YVSELALYDIRAAEGIGKDLSHINTNS 52
KVA + GAS G+G+ ++ LL A+ D G G L+ N S
Sbjct: 13 KVALVTGASRGIGKAIAELLAERGAKVIGTATSESGAQAISDYLGDNGKGMALNVTNPES 72
Query: 53 SCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKM 92
+I + +++ AG+ TRD+L
Sbjct: 73 IEAVL--KAITDEFGGVDILVNNAGI------TRDNLLMR 104
>2C54-A nrPDB
Length = 379
Score = 29.0 bits (63), Expect = 2.8, Method: Composition-based stats.
Identities = 13/69 (18%), Positives = 25/69 (36%), Gaps = 21/69 (30%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSP------------------YVSELALYDIRAAEG--- 40
+K++I GA G + ++ LK + E L D+R E
Sbjct: 30 LKISITGAGGFIASHIARRLKHEGHYVIASDWKKNEHMTEDMFCDEFHLVDLRVMENCLK 89
Query: 41 IGKDLSHIN 49
+ + + H+
Sbjct: 90 VTEGVDHVF 98
>6BI4-A nrPDB
Length = 346
Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats.
Identities = 11/79 (13%), Positives = 27/79 (34%), Gaps = 5/79 (6%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEG---IGKDLSHINTNSSCVGY- 57
+ + + G +G +G + S ++ +D G K + G
Sbjct: 25 MNILVTGGAGFIGSNFVHYMLQSYETYKIINFDALTYSGNLNNVKSIQDHPNYYFVKGEI 84
Query: 58 -DKDSIENTLSNAQVVLIP 75
+ + +E+ + V +I
Sbjct: 85 QNGELLEHVIKERDVQVIV 103
>1YS4-A nrPDB
Length = 354
Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats.
Identities = 20/74 (27%), Positives = 29/74 (39%), Gaps = 9/74 (12%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
+KV +LGA+G VGQ LL P AL + G +C +
Sbjct: 9 IKVGVLGATGSVGQRFVQLLADHPMFELTALAASERSAGK-------KYKDACYWFQDRD 61
Query: 62 IENTLSNAQVVLIP 75
I + +V+IP
Sbjct: 62 IPENIK--DMVVIP 73
>5JCP-B nrPDB
Length = 419
Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats.
Identities = 21/127 (16%), Positives = 43/127 (33%), Gaps = 19/127 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K+ I+G G G+ L++ E+ + + E D+ +D
Sbjct: 245 KLVIVG-DGACGKTCLLIVNSKDQFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 301
Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115
E+ + + V+L+ + D + I + V F PN I++
Sbjct: 302 EDYDRLRPLSYPDTDVILMCFSI------DSPDSLE---NIPEKWTPEVKHFCPNVPIIL 352
Query: 116 ISNPVNS 122
+ N +
Sbjct: 353 VGNKKDL 359
>3PZR-A nrPDB
Length = 370
Score = 29.0 bits (63), Expect = 3.2, Method: Composition-based stats.
Identities = 14/81 (17%), Positives = 24/81 (29%), Gaps = 13/81 (16%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDS 61
++V ++G G VG L + D E + S I + G D
Sbjct: 1 MRVGLVGWRGMVGSVLMQRMVEER--------DFDLIEPVFFSTSQIGVPAPNFGKDAGM 52
Query: 62 IENTL-----SNAQVVLIPAG 77
+ + V+ G
Sbjct: 53 LHDAFDIESLKQLDAVITCQG 73
>5G4J-A nrPDB
Length = 446
Score = 29.0 bits (63), Expect = 3.3, Method: Composition-based stats.
Identities = 17/132 (12%), Positives = 39/132 (29%), Gaps = 13/132 (9%)
Query: 150 LVRAETFLVDYLMLKNPKIGQEQDKTTMHRKVTVI----GGHSGETII--PIITDKSLVF 203
VRA + D + + +++ + GH + P+ + + L+
Sbjct: 170 HVRALR-IPDVSGIAEVDVPVLLEQSLADVDAAIASLQAAGHGVSVFLFDPLFSTEGLLQ 228
Query: 204 QLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKF------AEEVLRSFHNEKP 257
E RV+ G ++ + +G G + + + N P
Sbjct: 229 LPSGYIEGVATRVRAAGGLVISDEVQSGFGRTGSGMWGYQMFNVEPELVTMGKPMGNGHP 288
Query: 258 ETESLSAFVYLP 269
++ L
Sbjct: 289 IGAVVTTAELLD 300
>3PRY-A nrPDB
Length = 268
Score = 29.0 bits (63), Expect = 3.4, Method: Composition-based stats.
Identities = 24/113 (21%), Positives = 43/113 (38%), Gaps = 28/113 (24%)
Query: 164 KNPKIGQEQDKTTMHRKVTVIGGH---SGETIIPIITDKSLVFQLDKQY----------- 209
KN K+G +D T R ++ H SG+ + + S + + K
Sbjct: 153 KNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQV 212
Query: 210 --EHFIHRVQFGGDEIV------------KAKQGAGSATLSMAFAGAKFAEEV 248
F+ RV+ G E+V + K+ G + +S+ G + AE +
Sbjct: 213 ANSAFVERVRKRGFEVVYMTEPIDEYCVQQLKEFDGKSLVSVTKEGLELAENL 265
>3EMK-A nrPDB
Length = 246
Score = 29.0 bits (63), Expect = 3.5, Method: Composition-based stats.
Identities = 14/85 (16%), Positives = 33/85 (38%), Gaps = 7/85 (8%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K + GA+GG+G+ ++ L + L + + +L D++++
Sbjct: 9 KALVTGATGGLGEAIARALHAQGAIVGLHGTREEKLKELAAELGERIFVFPANLSDREAV 68
Query: 63 -------ENTLSNAQVVLIPAGVPR 80
E + +++ AG+ R
Sbjct: 69 KALGQKAEEEMGGVDILVNNAGITR 93
>2ZJ1-A nrPDB
Length = 495
Score = 28.6 bits (62), Expect = 3.6, Method: Composition-based stats.
Identities = 17/76 (22%), Positives = 31/76 (40%), Gaps = 14/76 (18%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYD-IRAAEGIGKDLSHINTNSSCVGYDKDS 61
KV I G G VG+ + +K + D I A + + + G+D +
Sbjct: 277 KVLICG-YGDVGKGCAEAMKGQGARVSVTEIDPINALQAMME------------GFDVVT 323
Query: 62 IENTLSNAQVVLIPAG 77
+E + +A +V+ G
Sbjct: 324 VEEAIGDADIVVTATG 339
>5TEN-A nrPDB
Length = 269
Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats.
Identities = 15/73 (20%), Positives = 30/73 (41%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKD 60
MV++A+ GA+G +G+ L +P A + + +G DL + D
Sbjct: 1 MVRIAVAGAAGRMGRNLVKAAHHNPVAKVAAGSERPESSLVGVDLGELCGEGKFDVVVCD 60
Query: 61 SIENTLSNAQVVL 73
+ + V++
Sbjct: 61 DLAKQIDQFDVII 73
>4G65-A nrPDB
Length = 461
Score = 28.6 bits (62), Expect = 3.8, Method: Composition-based stats.
Identities = 11/33 (33%), Positives = 18/33 (54%), Gaps = 3/33 (9%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYD 34
+K+ ILGA G VG L+ L +++ + D
Sbjct: 4 MKIIILGA-GQVGGTLAENLV--GENNDITIVD 33
>2R00-A nrPDB
Length = 336
Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats.
Identities = 15/39 (38%), Positives = 22/39 (56%), Gaps = 1/39 (2%)
Query: 4 VAILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGI 41
VAI GA+G VG+ + +L+ + V EL L +EG
Sbjct: 6 VAIFGATGAVGETMLEVLQEREFPVDELFLLASERSEGK 44
>2EP5-A nrPDB
Length = 350
Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats.
Identities = 13/30 (43%), Positives = 21/30 (70%), Gaps = 1/30 (3%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELA 31
+KV++LG++G VGQ + +L PY+ EL
Sbjct: 5 IKVSLLGSTGMVGQKMVKMLAKHPYL-ELV 33
>3TZ6-A nrPDB
Length = 344
Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats.
Identities = 16/75 (21%), Positives = 28/75 (37%), Gaps = 7/75 (9%)
Query: 4 VAILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
+ I+GA+G VGQ + LL + S + + ++G +D+
Sbjct: 4 IGIVGATGQVGQVMRTLLDERDFPASAVRFFASARSQGRKLAFRGQEIEV------EDAE 57
Query: 63 ENTLSNAQVVLIPAG 77
S + L AG
Sbjct: 58 TADPSGLDIALFSAG 72
>4MOW-A nrPDB
Length = 256
Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats.
Identities = 20/99 (20%), Positives = 37/99 (37%), Gaps = 10/99 (10%)
Query: 3 KVAIL-GASGGVGQPLSLLLKLSPYVSELALYDIRA-AEGIGKDLSHINTNSSCVGYDKD 60
KVAI+ GAS G+G ++ L + +A A+ + ++ + VG D
Sbjct: 15 KVAIVTGASKGIGAAIAKALADEGAAVVVNYASSKAGADAVVSAITEAGGRAVAVGGDVS 74
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKS 99
+ + G R D+ N+G+ +
Sbjct: 75 KAADAQRIVDTAIETYG--------RLDVLVNNSGVYEF 105
>2BKA-A nrPDB
Length = 242
Score = 28.6 bits (62), Expect = 4.3, Method: Composition-based stats.
Identities = 22/90 (24%), Positives = 32/90 (35%), Gaps = 7/90 (7%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDK-DSI 62
V ILGASG G+ L + S++ L R + ++N V ++K D
Sbjct: 21 VFILGASGETGRVLLKEILEQGLFSKVTLIGRRKLTFDEEAYKNVNQE--VVDFEKLDDY 78
Query: 63 ENTLSNAQVVLIPAGVPRK----PGLTRDD 88
+ V G R G R D
Sbjct: 79 ASAFQGHDVGFCCLGTTRGKAGAEGFVRVD 108
>3W9B-A nrPDB
Length = 328
Score = 28.6 bits (62), Expect = 4.4, Method: Composition-based stats.
Identities = 9/40 (22%), Positives = 21/40 (52%)
Query: 97 VKSLVTAVGKFAPNARILVISNPVNSLVPIAVETLKKMGK 136
++S V + FAP+ + V++ P+++L A ++
Sbjct: 128 IRSKVDRLMAFAPDYKGTVLAGPLDALAVSAPSVWQQTTG 167
>4YWJ-A nrPDB
Length = 276
Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats.
Identities = 13/74 (17%), Positives = 30/74 (40%), Gaps = 1/74 (1%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSEL-ALYDIRAAEGIGKDLSHINTNSSCVGYDK 59
M ++A++GA+G +G+ L ++ + + L A D + +G D +
Sbjct: 9 MRRIAVVGAAGRMGKNLIEAVQQTGGAAGLTAAVDRPDSTLVGADAGELAGLGRIGVPLS 68
Query: 60 DSIENTLSNAQVVL 73
+ V++
Sbjct: 69 GDLGKVCEEFDVLI 82
>2GAS-A nrPDB
Length = 307
Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats.
Identities = 27/116 (23%), Positives = 44/116 (37%), Gaps = 18/116 (15%)
Query: 3 KVAILGASGGVGQPLSLL-LKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGY---- 57
K+ ILG +G +G+ + +K L I AA K+ N S V
Sbjct: 4 KILILGPTGAIGRHIVWASIKAGNPTYALVRKTITAANPETKEELIDNYQSLGVILLEGD 63
Query: 58 --DKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSL--VTAVGKFAP 109
D +++ + +V+ AG R L + I+K++ V KF P
Sbjct: 64 INDHETLVKAIKQVDIVICAAG--------RL-LIEDQVKIIKAIKEAGNVKKFFP 110
>6BMQ-A nrPDB
Length = 523
Score = 28.6 bits (62), Expect = 4.6, Method: Composition-based stats.
Identities = 20/109 (18%), Positives = 37/109 (33%), Gaps = 2/109 (1%)
Query: 118 NPV-NSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETFLVDYLMLKNPKIGQEQDKTT 176
NP+ + I L + ++P G D L + L I E +
Sbjct: 45 NPLEDLKTIIKKSPLPTLFTYRPKWEGGQYEGDENERRDVLRLAMELGADYIDVELQVAS 104
Query: 177 MHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVK 225
K + G G+ + + + + + + R+Q G +IVK
Sbjct: 105 EFIKS-IDGKKPGKFKVIVSSHNYQNTPSVEDLDGLVARIQQTGADIVK 152
>5C2K-A nrPDB
Length = 415
Score = 28.2 bits (61), Expect = 4.8, Method: Composition-based stats.
Identities = 19/127 (14%), Positives = 41/127 (32%), Gaps = 18/127 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K ++ G G+ L++ E+ + + E D+ +D
Sbjct: 13 KKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 70
Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115
E+ + + V+L+ + D + I + V F PN I++
Sbjct: 71 EDYDRLRPLSYPDTDVILMCFSI------DSPDSLE---NIPEKWTPEVKHFCPNVPIIL 121
Query: 116 ISNPVNS 122
+ N +
Sbjct: 122 VGNKKDL 128
>5ZHX-e nrPDB
Length = 198
Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats.
Identities = 19/127 (14%), Positives = 41/127 (32%), Gaps = 18/127 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
K ++ G G+ L++ E+ + + E D+ +D
Sbjct: 11 KKLVIVGDGACGKTCLLIVFSKDQFPEVYVPTVF--ENYVADIEVDGKQVELALWDTAGQ 68
Query: 63 EN-------TLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILV 115
E+ + + V+L+ + D + I + V F PN I++
Sbjct: 69 EDYDRLRPLSYPDTDVILMCFSI------DSPDSLE---NIPEKWTPEVKHFCPNVPIIL 119
Query: 116 ISNPVNS 122
+ N +
Sbjct: 120 VGNKKDL 126
>3SXP-A nrPDB
Length = 362
Score = 28.2 bits (61), Expect = 4.9, Method: Composition-based stats.
Identities = 7/31 (22%), Positives = 16/31 (51%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYD 34
+ I G +G VG L+ + + +++ + D
Sbjct: 13 ILITGGAGFVGSNLAFHFQENHPKAKVVVLD 43
>2O3J-A nrPDB
Length = 481
Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats.
Identities = 25/130 (19%), Positives = 46/130 (35%), Gaps = 25/130 (19%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE------------GIGKDLSHINT 50
KV +GA G VG P ++ + + D+ A+ G D +
Sbjct: 11 KVVCVGA-GYVGGPTCAMIAHKCPHITVTVVDMNTAKIAEWNSDKLPIYEPGLD-EIVFA 68
Query: 51 NSSCVGYDKDSIENTLSNAQVVLIPAGVP-----RKPGLTRDDLFKMNAGIVKSLVTAVG 105
+ I ++ A ++ I P R G+ DL V+S+ +
Sbjct: 69 ARGRNLFFSSDIPKAIAEADLIFISVNTPTKMYGRGKGMA-PDL-----KYVESVSRTIA 122
Query: 106 KFAPNARILV 115
++A +I+V
Sbjct: 123 QYAGGPKIVV 132
>5FWK-A nrPDB
Length = 727
Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats.
Identities = 18/77 (23%), Positives = 30/77 (38%), Gaps = 16/77 (20%)
Query: 164 KNPKIGQEQDKTTMHRKVTVIGGH---SGETIIPIITDKSLVFQLDKQY----------- 209
KN K+G +D T R ++ H SG+ + + S + + K
Sbjct: 438 KNLKLGIHEDSTNRRRLSELLRYHTSQSGDEMTSLSEYVSRMKETQKSIYYITGESKEQV 497
Query: 210 --EHFIHRVQFGGDEIV 224
F+ RV+ G E+V
Sbjct: 498 ANSAFVERVRKRGFEVV 514
>2O23-A nrPDB
Length = 265
Score = 28.2 bits (61), Expect = 5.0, Method: Composition-based stats.
Identities = 15/84 (17%), Positives = 28/84 (33%), Gaps = 11/84 (13%)
Query: 5 AILGASGGVGQPLSLLLKLSPYVSELALYDIRA--AEGIGKDLSHINTNSSCVGYDKDSI 62
I G + G+G + L + L D+ E K L + + + +
Sbjct: 16 VITGGASGLGLATAERLVGQGASA--VLLDLPNSGGEAQAKKLGNNCVFAPADVTSEKDV 73
Query: 63 ENTLSNA-------QVVLIPAGVP 79
+ L+ A V + AG+
Sbjct: 74 QTALALAKGKFGRVDVAVNCAGIA 97
>1QWG-A nrPDB
Length = 251
Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats.
Identities = 17/66 (25%), Positives = 23/66 (34%), Gaps = 10/66 (15%)
Query: 67 SNAQVVLIPA-------GVPRKPG---LTRDDLFKMNAGIVKSLVTAVGKFAPNARILVI 116
+ A V+I G+ K G D+ N I K + A K A IL
Sbjct: 160 AGADYVIIEGRESGKGKGLFDKEGKVKENELDVLAKNVDINKVIFEAPQKSQQVAFILKF 219
Query: 117 SNPVNS 122
+ VN
Sbjct: 220 GSSVNL 225
>3I83-A nrPDB
Length = 320
Score = 28.2 bits (61), Expect = 5.2, Method: Composition-based stats.
Identities = 24/145 (16%), Positives = 47/145 (32%), Gaps = 26/145 (17%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELAL---YDIRAAEGIGKDLSHINTNSSCVGYDKD 60
+ ++G +G +G LL + + + Y+ A+GI + + +
Sbjct: 5 ILVIG-TGAIGSFYGALLAKTGHCVSVVSRSDYETVKAKGIRIRSATLGDYTFRPAAVVR 63
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNARILVISNPV 120
S + L+ V G R L + AP+ I++ISN +
Sbjct: 64 SAAELETKPDCTLLCIKV--VEGADRVGLLRD-------------AVAPDTGIVLISNGI 108
Query: 121 NSLVPIAVETLKKMGKFKPGNVMGV 145
+ +A F V+
Sbjct: 109 DIEPEVAAA-------FPDNEVISG 126
>2X86-A nrPDB
Length = 357
Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats.
Identities = 5/28 (17%), Positives = 10/28 (35%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELA 31
+ + G +G +G + L L
Sbjct: 49 IIVTGGAGFIGSNIVKALNDKGITDILV 76
>1EQ2-A nrPDB
Length = 310
Score = 28.2 bits (61), Expect = 5.5, Method: Composition-based stats.
Identities = 5/28 (17%), Positives = 10/28 (35%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELA 31
+ + G +G +G + L L
Sbjct: 2 IIVTGGAGFIGSNIVKALNDKGITDILV 29
>3UW3-A nrPDB
Length = 377
Score = 28.2 bits (61), Expect = 5.6, Method: Composition-based stats.
Identities = 12/78 (15%), Positives = 24/78 (30%), Gaps = 7/78 (8%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVS--ELALYDIRAAEGIGKDLSHINTNSSCVGYDK 59
+ V ++G G VG L ++ E + A G + +
Sbjct: 5 MNVGLVGWRGMVGSVLMQRMQEEGDFDLIEPVFFSTSNAGGKA-----PSFAKNETTLKD 59
Query: 60 DSIENTLSNAQVVLIPAG 77
+ + L V++ G
Sbjct: 60 ATSIDDLKKCDVIITCQG 77
>6EL3-D nrPDB
Length = 381
Score = 28.2 bits (61), Expect = 5.6, Method: Composition-based stats.
Identities = 21/109 (19%), Positives = 43/109 (39%), Gaps = 7/109 (6%)
Query: 6 ILGASGGVGQPLSLLLKLSPY-VSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIEN 64
I+G +G VG L+ +L LS +Y + + H C D + +
Sbjct: 24 IIGVTGIVGNSLAEILPLSDTPGGPWKVYGVARRPRPTWNADHPIDYIQCDVSDAEDTRS 83
Query: 65 T---LSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPN 110
L++ V R + + + N ++++++ A+ +APN
Sbjct: 84 KLSPLTDVTHVFYVTWTNR---ESESENCEANGSMLRNVLQAIIPYAPN 129
>2Z2C-A nrPDB
Length = 423
Score = 28.2 bits (61), Expect = 5.7, Method: Composition-based stats.
Identities = 32/184 (17%), Positives = 60/184 (32%), Gaps = 12/184 (6%)
Query: 165 NPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIV 224
P + + IG + I + +L++ Y + G IV
Sbjct: 98 GPLVARFGQGQVSLPGGCTIGARPVDLHISGLEQLGATIKLEEGYVKASVDGRLKGAHIV 157
Query: 225 KAKQGAGSATLSMAFAGAKFAEEVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDN 284
K G+ M A ++ + E PE + F+ G K + +
Sbjct: 158 MDKVSVGATVTIMCAATLAEGTTIIENAARE-PEIVDTANFLITLGAKISGQGTDRIVIE 216
Query: 285 SIEYFS------LPIVLRNGSVVSIDTSVLEKLSPREEQ--LVNTAVKELR---KNIEKG 333
+E LP + G+ + K+ R Q ++ + +LR +IE G
Sbjct: 217 GVERLGGGVYRVLPDRIETGTFLVAAAISRGKIICRNAQPDTLDAVLAKLRDAGADIEVG 276
Query: 334 KSFI 337
+ +I
Sbjct: 277 EDWI 280
>3PWS-A nrPDB
Length = 366
Score = 28.2 bits (61), Expect = 5.8, Method: Composition-based stats.
Identities = 18/74 (24%), Positives = 31/74 (41%), Gaps = 5/74 (6%)
Query: 4 VAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSIE 63
VA++GA+G VG + +L+ S + Y + +A GK L +++ E
Sbjct: 5 VAVVGATGAVGAQMIKMLEESTLPIDKIRY-LASARSAGKSLK----FKDQDITIEETTE 59
Query: 64 NTLSNAQVVLIPAG 77
+ L AG
Sbjct: 60 TAFEGVDIALFSAG 73
>3N58-A nrPDB
Length = 464
Score = 28.2 bits (61), Expect = 5.9, Method: Composition-based stats.
Identities = 15/75 (20%), Positives = 30/75 (40%), Gaps = 11/75 (14%)
Query: 3 KVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAEGIGKDLSHINTNSSCVGYDKDSI 62
KVA++ G VG+ + L + ++ D A D G++ ++
Sbjct: 248 KVAVVCGYGDVGKGSAQSLAGAGARVKVTEVDPICALQAAMD-----------GFEVVTL 296
Query: 63 ENTLSNAQVVLIPAG 77
++ S A +V+ G
Sbjct: 297 DDAASTADIVVTTTG 311
>1MV8-A nrPDB
Length = 436
Score = 27.8 bits (60), Expect = 6.3, Method: Composition-based stats.
Identities = 16/94 (17%), Positives = 31/94 (32%), Gaps = 19/94 (20%)
Query: 2 VKVAILGASGGVGQPLSLLLKLSPYVSELALYDIRAAE--------------GIGKDLSH 47
++++I G G VG + L + E+ D+ + + G+ L
Sbjct: 1 MRISIFGL-GYVGAVCAGCLSARGH--EVIGVDVSSTKIDLINQGKSPIVEPGLEALLQQ 57
Query: 48 INTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRK 81
G + + ++ V I G P K
Sbjct: 58 GRQTGRLSG--TTDFKKAVLDSDVSFICVGTPSK 89
>4RFL-A nrPDB
Length = 371
Score = 27.8 bits (60), Expect = 6.7, Method: Composition-based stats.
Identities = 16/116 (13%), Positives = 37/116 (31%), Gaps = 3/116 (2%)
Query: 187 HSGETIIPIITDKSLVFQLDKQYEHFIHRVQFGGDEIVKAKQGAGSATLSMAFAGAKFAE 246
H II + + E + ++ ++ K F + +
Sbjct: 33 HPFTMIIVTPRYTIIEDGAINKIEEILKKLNLKNPLVITGKNTKKYCRF---FYDIVYYD 89
Query: 247 EVLRSFHNEKPETESLSAFVYLPGLKNGKKAQQLVGDNSIEYFSLPIVLRNGSVVS 302
E+L + E + + + + G ++ + L I + S+P N + S
Sbjct: 90 EILNNLEIELKKYTAYDCVIGIGGGRSIDTGKYLAYKLGIPFISVPTTASNDGIAS 145
>3SQG-A nrPDB
Length = 579
Score = 27.8 bits (60), Expect = 7.0, Method: Composition-based stats.
Identities = 9/36 (25%), Positives = 18/36 (50%)
Query: 76 AGVPRKPGLTRDDLFKMNAGIVKSLVTAVGKFAPNA 111
G+ +K G+ + + + IV S V + + P+A
Sbjct: 33 GGIAQKGGMRKREFIAEASKIVDSRVNSTPAYNPDA 68
>3EH7-A nrPDB
Length = 434
Score = 27.8 bits (60), Expect = 7.6, Method: Composition-based stats.
Identities = 36/198 (18%), Positives = 69/198 (34%), Gaps = 8/198 (4%)
Query: 38 AEGIGKDLSHINTNSSCVGYDKDSIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMNAGIV 97
EG + + + + IP P + R D+ ++ IV
Sbjct: 66 GEGKYMAPEMAPHFRHITNFVGGNSRKAVEENRADFIPVFFYEVPSMIRKDILHIDVAIV 125
Query: 98 KSLVTAVGKFAPNARILVISNP-VNSLVPIAVETLKKMGKFKPGNVMGVTNLDLVRAETF 156
+ + + S P S + E ++M N++ ++ LD +
Sbjct: 126 QLSMPDENGYCSFGVSCDYSKPAAESAHLVIGEINRQMPYVHGDNLIHISKLDYI----V 181
Query: 157 LVDY--LMLKNPKIGQEQDKTTMHRKVTVIGGHSGETIIPIITDKSLVFQLDKQYEHF-I 213
+ DY L PKIG+ ++ + + G + + I I D +L+F DK+
Sbjct: 182 MADYPIYSLAKPKIGEVEEAIGRNCAELIEDGATLQLGIGAIPDAALLFLKDKKDLGIHT 241
Query: 214 HRVQFGGDEIVKAKQGAG 231
G E+V++ G
Sbjct: 242 EMFSDGVVELVRSGVITG 259
>4J6F-A nrPDB
Length = 382
Score = 27.4 bits (59), Expect = 8.6, Method: Composition-based stats.
Identities = 12/40 (30%), Positives = 20/40 (50%), Gaps = 8/40 (20%)
Query: 4 VAILGASGGVGQPL--------SLLLKLSPYVSELALYDI 35
V + GASGGVG + ++ + ++ E A+ DI
Sbjct: 210 VLVTGASGGVGSAIIQLARARGAVPIAVAGPGKEAAMLDI 249
>4WOJ-A nrPDB
Length = 370
Score = 27.4 bits (59), Expect = 8.7, Method: Composition-based stats.
Identities = 9/28 (32%), Positives = 12/28 (42%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVS 28
M+KV +G G VG L + S
Sbjct: 7 MLKVGFIGWRGMVGSVLMSRMIESKDFD 34
>6QUZ-A nrPDB
Length = 587
Score = 27.4 bits (59), Expect = 9.0, Method: Composition-based stats.
Identities = 9/30 (30%), Positives = 17/30 (56%)
Query: 1 MVKVAILGASGGVGQPLSLLLKLSPYVSEL 30
M+ VA++GA GG+G + + ++L
Sbjct: 69 MLIVALIGAVGGIGCTVFASYASQNFGADL 98
>3Q98-A nrPDB
Length = 399
Score = 27.4 bits (59), Expect = 9.0, Method: Composition-based stats.
Identities = 9/33 (27%), Positives = 15/33 (45%)
Query: 61 SIENTLSNAQVVLIPAGVPRKPGLTRDDLFKMN 93
S+E +A +V + P K R +L + N
Sbjct: 259 SMEEAFKDADIVYPKSWAPYKVMEERTELLRAN 291
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.313 0.126 0.315
Lambda K H
0.267 0.0381 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,292,759
Number of Sequences: 36641
Number of extensions: 426771
Number of successful extensions: 2450
Number of sequences better than 10.0: 181
Number of HSP's better than 10.0 without gapping: 167
Number of HSP's successfully gapped in prelim test: 107
Number of HSP's that attempted gapping in prelim test: 1782
Number of HSP's gapped (non-prelim): 288
length of query: 343
length of database: 10,336,785
effective HSP length: 98
effective length of query: 245
effective length of database: 6,745,967
effective search space: 1652761915
effective search space used: 1652761915
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 59 (27.4 bits)