BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P32340 (513 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4G74-A nrPDB 1004 0.0 5JWC-A nrPDB 191 6e-49 5NA1-A nrPDB 132 4e-31 2NVK-X nrPDB 46 3e-05 3HYW-A nrPDB 44 1e-04 3OC4-A nrPDB 41 0.001 3ICS-A nrPDB 41 0.001 3LXD-A nrPDB 40 0.003 3T14-A nrPDB 40 0.003 1NHQ-A nrPDB 40 0.003 1LVL-A nrPDB 39 0.004 3H8L-A nrPDB 39 0.005 4YKF-A nrPDB 38 0.009 1FL2-A nrPDB 38 0.011 3NTA-A nrPDB 37 0.019 2R9Z-A nrPDB 37 0.020 3LAD-A nrPDB 36 0.037 3Q6J-A nrPDB 36 0.045 5TR3-A nrPDB 35 0.074 2CDU-A nrPDB 35 0.081 2V3B-A nrPDB 35 0.082 1GEU-A nrPDB 34 0.14 2HQM-A nrPDB 33 0.23 2YVG-A nrPDB 33 0.43 1XHC-A nrPDB 32 0.76 5ER0-A nrPDB 32 0.83 3ZK8-A nrPDB 32 0.95 3CGD-A nrPDB 32 0.98 3VEW-A nrPDB 31 1.2 1EBD-A nrPDB 31 1.2 4UTP-A nrPDB 31 1.2 6BRD-A nrPDB 31 1.5 4YRY-B nrPDB 30 1.9 6MO6-A nrPDB 30 2.1 5NLG-A nrPDB 30 2.1 4Z44-A nrPDB 30 2.3 5WUG-A nrPDB 30 2.6 5C9S-B nrPDB 30 2.9 4FX9-A nrPDB 30 3.3 2GMH-A nrPDB 30 3.3 5KOX-A nrPDB 29 3.8 3IWA-A nrPDB 29 4.5 2BC1-A nrPDB 29 4.9 3FKQ-A nrPDB 29 5.1 6IHE-A nrPDB 29 5.6 2NZW-A nrPDB 28 6.7 1FOH-A nrPDB 28 9.3 5JCN-A nrPDB 28 9.5 >4G74-A nrPDB Length = 502 Score = 1004 bits (2596), Expect = 0.0, Method: Compositional matrix adjust. Identities = 490/491 (99%), Positives = 491/491 (100%) Query: 23 ASTRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSII 82 +STRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSII Sbjct: 12 SSTRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSII 71 Query: 83 SPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIK 142 SPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIK Sbjct: 72 SPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIK 131 Query: 143 SLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL 202 SLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL Sbjct: 132 SLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL 191 Query: 203 EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPAL 262 EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPAL Sbjct: 192 EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPAL 251 Query: 263 AEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHED 322 AEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHED Sbjct: 252 AEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHED 311 Query: 323 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG 382 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG Sbjct: 312 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG 371 Query: 383 DNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYN 442 DNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYN Sbjct: 372 DNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYN 431 Query: 443 DLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKL 502 DLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKL Sbjct: 432 DLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKL 491 Query: 503 AFFKRDFFKGL 513 AFFKRDFFKGL Sbjct: 492 AFFKRDFFKGL 502 >5JWC-A nrPDB Length = 521 Score = 191 bits (485), Expect = 6e-49, Method: Compositional matrix adjust. Identities = 121/339 (35%), Positives = 185/339 (54%), Gaps = 32/339 (9%) Query: 53 KPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIV 112 K ++ILGSGWG +FL +ID KKY+V++ISPR+YF FTPLLP GT+ E I Sbjct: 28 KEKIIILGSGWGGFNFLLNIDFKKYDVTLISPRNYFTFTPLLPCLCSGTLSVNVCTESIR 87 Query: 113 NFALKKKGNV-TYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIK--Y 169 NF KK G Y + E T + + + ++ E ++K Y Sbjct: 88 NFLRKKNGYCGNYLQLECTDV------------------FYEDKYINCIDIENNKVKLFY 129 Query: 170 DYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 DYLI AVGA+ NTF I GV Y +F+K+I ++L+IR+ F LEK L + E++++L Sbjct: 130 DYLIIAVGAKTNTFNINGVDKYAYFVKDIDDALKIRKKFLDILEKCTLPNISNEEKKKML 189 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 + VVGGGPTGVE E D+++++++ + + I ++E +L F + +S + Sbjct: 190 HVAVVGGGPTGVEVTAEFADFINKEVKINYKDIFNFISISIIEGGNNLLPTFTQNISDFT 249 Query: 290 QSHLENTSIKVHLRTAVAKVEEKQLLAKT---KHEDGKITEETIPYGTLIWATGNKARPV 346 + + N +I V V V++ ++ K+E K++ YG LIWA+G + Sbjct: 250 KENFHNLNINVLTNYYVIDVDKHSFHIQSSLNKNEKKKLS-----YGLLIWASGLAQTTL 304 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKG--SNNIFAIGD 383 I K IP Q ++ L V++ L+V G SNNI+AIGD Sbjct: 305 IQKFLKTIPVQ-ANNAILKVDEKLRVIGIPSNNIYAIGD 342 >5NA1-A nrPDB Length = 408 Score = 132 bits (332), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 116/427 (27%), Positives = 198/427 (46%), Gaps = 84/427 (19%) Query: 52 DKPNVLILGSGWGAISFL----KHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSI 107 D+ VL+LG+G+ + + K I T++ +++I+ Y L A GT++ + + Sbjct: 10 DRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNYEDV 69 Query: 108 IEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEI 167 + P+ ++ KK V + +AE T I+ D V E + G++ Sbjct: 70 LYPVE--SVLKKDKVNFVQAEVTKIDRDAKKV--------------ETNQGIYD------ 107 Query: 168 KYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRR-------TFAANLEKANLLPK 220 +D L+ A+G TFGI G+ D+ ++ + + E+ R +AA+ EK + Sbjct: 108 -FDILVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDD---- 162 Query: 221 GDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNM 280 LSI+V G G TGVE GEL D + + K+ +V+I VEA P +L M Sbjct: 163 ------NDLSILVGGAGFTGVEFLGELTDRIPELCSKY-GVDQNKVKITCVEAAPKMLPM 215 Query: 281 FEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATG 340 F ++L ++A S+LE+ ++ + T + EK + + E ++ + GT +WA G Sbjct: 216 FSEELVNHAVSYLEDRGVEFKIATPIVACNEKGFVVEVDGE-----KQQLNAGTSVWAAG 270 Query: 341 NKARPVITDLFKKIPEQNSSKRG-LAVNDFLQVKGSNNIFAIGD-NAF--AG----LPPT 392 + ++ + F+ + KRG + L + G +NIF IGD +AF AG LP T Sbjct: 271 VRGSKLMEESFEGV------KRGRIVTKQDLTINGYDNIFVIGDCSAFIPAGEERPLPTT 324 Query: 393 AQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGS 452 AQ+A Q+ E +AKN I + + + F+Y D G + LGS Sbjct: 325 AQIAMQQGESVAKN--------------------IKRILNGESTEEFEYVDRGTVCSLGS 364 Query: 453 ERAIATI 459 + + Sbjct: 365 HDGVGMV 371 >2NVK-X nrPDB Length = 488 Score = 46.2 bits (108), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 63/246 (25%), Positives = 98/246 (39%), Gaps = 60/246 (24%) Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 + AVG P IPG +YG ++ F+ + E L Sbjct: 154 FVIAVGGRPRYPDIPGAVEYGITSDDL---------FSLDREPGKTL------------- 191 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 291 VVG G G+E AG FL L E + + IVL F+++++ + Sbjct: 192 -VVGAGYIGLECAG------------FLKGLGYEPTVMVRS---IVLRGFDQQMAELVAA 235 Query: 292 HLENTSIKVHLRT---AVAKVEEKQLLAKTKH-EDGKITEETIPYGTLIWATGNKARPVI 347 +E I +T +V K ++ +LL K K+ E G+ +E+ Y T++WA G K ++ Sbjct: 236 SMEERGIPFLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDV--YDTVLWAIGRKG--LV 291 Query: 348 TDLFKKIPEQNSSKRGLAVN------DFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 DL N G+ V D + NI+A+GD + G P VA Sbjct: 292 DDL-------NLPNAGVTVQKDKIPVDSQEATNVANIYAVGDIIY-GKPELTPVAVLAGR 343 Query: 402 YLAKNF 407 LA+ Sbjct: 344 LLARRL 349 >3HYW-A nrPDB Length = 430 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 32/99 (32%), Positives = 46/99 (46%), Gaps = 22/99 (22%) Query: 79 VSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNT 138 +++IS R YF FTP P +G + I P+ L K N+ + +A SI+PD NT Sbjct: 30 ITLISDRPYFGFTPAFPHLAMGWRKFEDISVPLA--PLLPKFNIEFINEKAESIDPDANT 87 Query: 139 VTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVG 177 VT +S +I+YDYL+ A G Sbjct: 88 VTTQSGK--------------------KIEYDYLVIATG 106 >3OC4-A nrPDB Length = 452 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 46/168 (27%), Positives = 77/168 (45%), Gaps = 29/168 (17%) Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSY 288 ++ V+G GP G+EA FL + + V H+ E+L +L F+K++ + Sbjct: 149 TVAVIGAGPIGMEAI------------DFLVKMKKTV--HVFESLENLLPKYFDKEMVAE 194 Query: 289 AQSHLENTSIKVHLRTAVAKVEEKQ--LLAKTKHEDGKITEETIPYGTLIWATGNKARPV 346 Q LE ++ H V +EE ++ +T +E+ I + I+A P Sbjct: 195 VQKSLEKQAVIFHFEETVLGIEETANGIVLET-------SEQEISCDSGIFAL--NLHPQ 245 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQ 394 + L KKI Q + + +AV+ +LQ N+FAIGD P A+ Sbjct: 246 LAYLDKKI--QRNLDQTIAVDAYLQT-SVPNVFAIGDCISVMNEPVAE 290 >3ICS-A nrPDB Length = 588 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 55/259 (21%), Positives = 103/259 (39%), Gaps = 56/259 (21%) Query: 127 AEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIP 186 +E IN + T+TIK+++ ++ Y YD LI + GA+P IP Sbjct: 114 SEVVKINKEEKTITIKNVTT-NETYNE--------------AYDVLILSPGAKPIVPSIP 158 Query: 187 GVTDYGHF--LKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAA 244 G+ + L+ +P++ I+ + ++ V+GGG GVE Sbjct: 159 GIEEAKALFTLRNVPDTDRIKAYI---------------DEKKPRHATVIGGGFIGVEMV 203 Query: 245 GELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRT 304 L++ +++ LVE V+ + ++++Y H++N +++ Sbjct: 204 ENLRE--------------RGIEVTLVEMANQVMPPIDYEMAAYVHEHMKNHDVELVFED 249 Query: 305 AVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGL 364 V +EE + + K + I LI A G + + L K + + Sbjct: 250 GVDALEENGAVVRLK------SGSVIQTDMLILAIGVQPE---SSLAKGAGLALGVRGTI 300 Query: 365 AVNDFLQVKGSNNIFAIGD 383 VN+ Q +I+AIGD Sbjct: 301 KVNEKFQTS-DPHIYAIGD 318 >3LXD-A nrPDB Length = 415 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 104/264 (39%), Gaps = 67/264 (25%) Query: 127 AEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIP 186 AE S++P +TV + SA I+Y LI A G +P Sbjct: 86 AEVVSLDPAAHTVKLGDGSA--------------------IEYGKLIWATGGDPRRLSCV 125 Query: 187 GVTDYG-HFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAG 245 G G H ++ ++ + A + A VV+GGG G+EAA Sbjct: 126 GADLAGVHAVRTKEDADRLMAELDAGAKNA----------------VVIGGGYIGLEAAA 169 Query: 246 ELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQSHLENTSIKVHLRT 304 L + V + L+EALP VL + + LS + Q+ E+ + V LRT Sbjct: 170 VLTKF--------------GVNVTLLEALPRVLARVAGEALSEFYQA--EHRAHGVDLRT 213 Query: 305 AVAK--VE-EKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSK 361 A +E + + + +DG + IP +I G ++ + I S Sbjct: 214 GAAMDCIEGDGTKVTGVRMQDGSV----IPADIVIVGIG-----IVPCVGALISAGASGG 264 Query: 362 RGLAVNDFLQVKGSNNIFAIGDNA 385 G+ V++F + +++AIGD A Sbjct: 265 NGVDVDEFCRTS-LTDVYAIGDCA 287 >3T14-A nrPDB Length = 437 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 37/158 (23%), Positives = 63/158 (39%), Gaps = 25/158 (15%) Query: 55 NVLILGSGWGAISF---LKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPI 111 +V+ILG+G G + +K + V++IS YF F P P VG + I PI Sbjct: 6 HVVILGAGTGGMPAAYEMKEALGSGHEVTLISANDYFQFVPSNPWVGVGWKERDDIAFPI 65 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 ++ +K + + A I+ + +T+ A+ + YDY Sbjct: 66 RHYVERK--GIHFIAQSAEQIDAEAQNITL--------------------ADGNTVHYDY 103 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFA 209 L+ A G + +PG + ++ I R FA Sbjct: 104 LMIATGPKLAFENVPGSDPHEGPVQSIATVDHAERAFA 141 >1NHQ-A nrPDB Length = 447 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 40/130 (30%), Positives = 61/130 (46%), Gaps = 31/130 (23%) Query: 116 LKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISA 175 ++ +G + E T+I P + VT+K L VS + EN YD LI + Sbjct: 66 MESRGVNVFSNTEITAIQPKEHQVTVKDL--VSGEERVEN-------------YDKLIIS 110 Query: 176 VGAEPNTFGIPGVTDYGHFLKEIPNSLEIR-RTFAANLEKANLLPKGDPERRRLLSIVVV 234 GA P IPG K++ N +R R +A L++ + DPE + ++VV+ Sbjct: 111 PGAVPFELDIPG--------KDLDNIYLMRGRQWAIKLKQKTV----DPE---VNNVVVI 155 Query: 235 GGGPTGVEAA 244 G G G+EAA Sbjct: 156 GSGYIGIEAA 165 >1LVL-A nrPDB Length = 458 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 50/189 (26%), Positives = 82/189 (43%), Gaps = 28/189 (14%) Query: 217 LLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPI 276 L PK P+ +VVVGGG G+E + RK Q+ +VEA Sbjct: 165 LAPKALPQH-----LVVVGGGYIGLE--------LGIAYRKL------GAQVSVVEARER 205 Query: 277 VLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLI 336 +L ++ +L++ L+ I +HL +V E LLA DGK + + ++ Sbjct: 206 ILPTYDSELTAPVAESLKKLGIALHLGHSVEGYENGCLLAN----DGKGGQLRLEADRVL 261 Query: 337 WATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVA 396 A G RP + + + +A+++ Q +N++AIGD AG P A A Sbjct: 262 VAVGR--RPRTKGFNLECLDLKMNGAAIAIDERCQTS-MHNVWAIGD--VAGEPMLAHRA 316 Query: 397 HQEAEYLAK 405 + E +A+ Sbjct: 317 MAQGEMVAE 325 >3H8L-A nrPDB Length = 409 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 41/156 (26%), Positives = 73/156 (46%), Gaps = 25/156 (16%) Query: 56 VLILGSGWGAISF---LKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGT--VDEKSIIEP 110 VL+LG +GA++ LK + K +V +I+ + F P LP +G VDE + Sbjct: 4 VLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVD-- 61 Query: 111 IVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 ++ AL +KG + + E I+ + S++ +P+ + AE +YD Sbjct: 62 -LSEALPEKG-IQFQEGTVEKID---------AKSSMVYYTKPDGSM-------AEEEYD 103 Query: 171 YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRR 206 Y+I +GA T + G YG+ + E + ++R Sbjct: 104 YVIVGIGAHLATELVKGWDKYGYSVCEPEFATKLRE 139 >4YKF-A nrPDB Length = 521 Score = 38.1 bits (87), Expect = 0.009, Method: Compositional matrix adjust. Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 27/161 (16%) Query: 127 AEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAE---IKYDYLISAVGAEPNTF 183 A A ++ D V + + S+L GLHQ E A +K +I A GA+ Sbjct: 270 AGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNM 329 Query: 184 GIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEA 243 +PG Y RT + P D + + V+GGG +GVEA Sbjct: 330 NVPGEDQY--------------RT-----KGVTYCPHCDGPLFKGKRVAVIGGGNSGVEA 370 Query: 244 AGELQDYV-HQDLRKFLPAL-AEEV---QIHLVEALPIVLN 279 A +L V H L +F P + A++V ++ ++ + I+LN Sbjct: 371 AIDLAGIVEHVTLLEFAPEMKADQVLQDKLRSLKNVDIILN 411 >1FL2-A nrPDB Length = 310 Score = 37.7 bits (86), Expect = 0.011, Method: Compositional matrix adjust. Identities = 44/161 (27%), Positives = 69/161 (42%), Gaps = 27/161 (16%) Query: 127 AEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAE---IKYDYLISAVGAEPNTF 183 A A ++ D V + + S+L GLHQ E A +K +I A GA+ Sbjct: 59 AGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWRNM 118 Query: 184 GIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEA 243 +PG Y RT + P D + + V+GGG +GVEA Sbjct: 119 NVPGEDQY--------------RT-----KGVTYCPHCDGPLFKGKRVAVIGGGNSGVEA 159 Query: 244 AGELQDYV-HQDLRKFLPAL-AEEV---QIHLVEALPIVLN 279 A +L V H L +F P + A++V ++ ++ + I+LN Sbjct: 160 AIDLAGIVEHVTLLEFAPEMKADQVLQDKLRSLKNVDIILN 200 >3NTA-A nrPDB Length = 574 Score = 37.0 bits (84), Expect = 0.019, Method: Compositional matrix adjust. Identities = 64/264 (24%), Positives = 104/264 (39%), Gaps = 59/264 (22%) Query: 169 YDYLISAVGAEPNTFGIPGVTD-YGHFLKEIPNSLEIRRTFAA-NLEKANLLPKGDPERR 226 YD L+ + GA P IPGV + H L+ IP+ I +T N+E A Sbjct: 106 YDTLLLSPGAAPIVPPIPGVDNPLTHSLRNIPDMDRILQTIQMNNVEHAT---------- 155 Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 VVGGG G+E L H ++ L LA++ V+ +++++ Sbjct: 156 ------VVGGGFIGLEMMESLH---HLGIKTTLLELADQ-----------VMTPVDREMA 195 Query: 287 SYAQSHLENTSIKVHLRTAVAKVE---EKQLLAKTKHED-------GKIT-----EETIP 331 +A + + + + L TA+++V + + + ED G ++ E + Sbjct: 196 GFAHQAIRDQGVDLRLGTALSEVSYQVQTHVASDAAGEDTAHQHIKGHLSLTLSNGELLE 255 Query: 332 YGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD-------- 383 LI A G RP T L + G+ VN +Q I+A+GD Sbjct: 256 TDLLIMAIG--VRPE-TQLARDAGLAIGELGGIKVNAMMQTS-DPAIYAVGDAVEEQDFV 311 Query: 384 NAFAGLPPTAQVAHQEAEYLAKNF 407 A L P A A+++ A N Sbjct: 312 TGQACLVPLAGPANRQGRMAADNM 335 >2R9Z-A nrPDB Length = 463 Score = 37.0 bits (84), Expect = 0.020, Method: Compositional matrix adjust. Identities = 37/153 (24%), Positives = 61/153 (39%), Gaps = 19/153 (12%) Query: 231 IVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQ 290 + ++G G G+E AG L+ + EV + +E +L F+ LS+ Sbjct: 169 VAIIGAGYIGIELAGLLRSF------------GSEVTVVALEDR--LLFQFDPLLSATLA 214 Query: 291 SHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDL 350 ++ I+ HL AVA +E +DG E + ++IWA G P DL Sbjct: 215 ENMHAQGIETHLEFAVAALERDAQGTTLVAQDGTRLEG---FDSVIWAVGRA--PNTRDL 269 Query: 351 FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 + G+ D Q ++A+GD Sbjct: 270 GLEAAGIEVQSNGMVPTDAYQNTNVPGVYALGD 302 >3LAD-A nrPDB Length = 476 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 12/137 (8%) Query: 267 QIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHL--RTAVAKVEEKQLLAKTKHEDGK 324 ++ ++EA+ L +++++ AQ L +K+ L R +V+ KQ+ K +G Sbjct: 205 EVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLGARVTGTEVKNKQVTVKFVDAEG- 263 Query: 325 ITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDN 384 E++ + LI A G RPV TDL +RG D ++AIGD Sbjct: 264 --EKSQAFDKLIVAVGR--RPVTTDLLAADSGVTLDERGFIYVDDYCATSVPGVYAIGD- 318 Query: 385 AFAGLPPTAQVAHQEAE 401 + A +AH+ +E Sbjct: 319 ----VVRGAMLAHKASE 331 >3Q6J-A nrPDB Length = 523 Score = 35.8 bits (81), Expect = 0.045, Method: Compositional matrix adjust. Identities = 66/302 (21%), Positives = 118/302 (39%), Gaps = 72/302 (23%) Query: 111 IVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 I+NF K++ N+ Y +N + ++ A ++++ +N Sbjct: 139 IMNFQSKEQLNLEYI------LNCPAKVIDNHTVEAAGKVFKAKN--------------- 177 Query: 171 YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLS 230 LI AVGA P T +PGV G F + A L+ + D E + Sbjct: 178 -LILAVGAGPGTLDVPGVNAKGVF------------------DHATLVEELDYEPGS--T 216 Query: 231 IVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQ 290 +VVVGG T VE F A + LV P+ L + + + +Y Sbjct: 217 VVVVGGSKTAVEYG------------CFFNATGRRT-VMLVRTEPLKL-IKDNETRAYVL 262 Query: 291 SHLENTSIKVHLRTAVAKVEE------KQLLAKTKHEDGKITEETIPYGTLIWATGNKAR 344 ++ +++ + V ++EE + ++A T + + +I + + G + Sbjct: 263 DRMKEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGEMRIETDFVFLGL-------GEQ 315 Query: 345 PVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLA 404 P +L K + K + VN++LQ N++A+GD G P A + Y A Sbjct: 316 PRSAELAKILGLDLGPKGEVLVNEYLQTS-VPNVYAVGD--LIGGPMEMFKARKSGCYAA 372 Query: 405 KN 406 +N Sbjct: 373 RN 374 >5TR3-A nrPDB Length = 481 Score = 35.0 bits (79), Expect = 0.074, Method: Compositional matrix adjust. Identities = 34/120 (28%), Positives = 55/120 (45%), Gaps = 9/120 (7%) Query: 267 QIHLVEALPIVLNMFEKKLSSYAQSHL--ENTSIKVHLRTAVAKVEEKQLLAKTKHEDGK 324 ++ ++EAL L + +S AQ L + IK+ R +KV ++ + +G Sbjct: 209 EVTVLEALDTFLMAADTAVSKEAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTYTNAEG- 267 Query: 325 ITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRG-LAVNDFLQVKGSNNIFAIGD 383 E+ I + LI A G RPV TDL +RG + V+D+ ++AIGD Sbjct: 268 --EQKITFDKLIVAVGR--RPVTTDLLASDSGVTIDERGYIFVDDYCATS-VPGVYAIGD 322 >2CDU-A nrPDB Length = 452 Score = 35.0 bits (79), Expect = 0.081, Method: Compositional matrix adjust. Identities = 63/271 (23%), Positives = 102/271 (37%), Gaps = 55/271 (20%) Query: 128 EATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPG 187 + T+++P+ T+ +K L + E E YD LI G++P IPG Sbjct: 80 QVTNVDPETKTIKVKDL--------------ITNEEKTE-AYDKLIMTTGSKPTVPPIPG 124 Query: 188 VTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGEL 247 + R N A L + P+ + +I ++G G G E A Sbjct: 125 ID-------------SSRVYLCKNYNDAKKLFEEAPKAK---TITIIGSGYIGAELA--- 165 Query: 248 QDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQSHLENTSIKVHLRTAV 306 + Y +Q+ ++L++ VL F+K+ + E + + L + V Sbjct: 166 EAYSNQNY-----------NVNLIDGHERVLYKYFDKEFTDILAKDYEAHGVNLVLGSKV 214 Query: 307 AKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAV 366 A EE TK DGK + I I G RP L K+ ++ G + Sbjct: 215 AAFEEVDDEIITKTLDGKEIKSDIA----ILCIG--FRPNTELLKGKVAMLDN---GAII 265 Query: 367 NDFLQVKGSNNIFAIGDNAFAGLPPTAQVAH 397 D + +IFA GD+A PT A+ Sbjct: 266 TDEYMHSSNRDIFAAGDSAAVHYNPTNSNAY 296 >2V3B-A nrPDB Length = 384 Score = 35.0 bits (79), Expect = 0.082, Method: Compositional matrix adjust. Identities = 67/261 (25%), Positives = 107/261 (40%), Gaps = 57/261 (21%) Query: 166 EIKYDYLISAVGAEPNTFGIPG-VTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPE 224 E++Y L+ A GAEP + G D + + ++ + R+ A Sbjct: 99 EVRYRDLVLAWGAEPIRVPVEGDAQDALYPINDLEDYARFRQAAAG-------------- 144 Query: 225 RRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKK 284 +RR+L ++G G G E A +L +Q L +A Q+ +P +L+ K Sbjct: 145 KRRVL---LLGAGLIGCEFANDLSSGGYQ-----LDVVAPCEQV-----MPGLLHPAAAK 191 Query: 285 LSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKAR 344 Q+ LE ++ HL +A +++ + DG E IP ++ A G + R Sbjct: 192 ---AVQAGLEGLGVRFHLGPVLASLKKAGEGLEAHLSDG----EVIPCDLVVSAVGLRPR 244 Query: 345 PVITDLFKKIPEQNSSKRGLAVNDFLQVKGS-----NNIFAIGDNA-FAGL-----PPTA 393 T+L + GLAVN + V S NI+A+GD A GL P Sbjct: 245 ---TEL--------AFAAGLAVNRGIVVDRSLRTSHANIYALGDCAEVDGLNLLYVMPLM 293 Query: 394 QVAHQEAEYLAKNFDKMAQIP 414 A A+ LA N ++A P Sbjct: 294 ACARALAQTLAGNPSQVAYGP 314 >1GEU-A nrPDB Length = 450 Score = 34.3 bits (77), Expect = 0.14, Method: Compositional matrix adjust. Identities = 62/234 (26%), Positives = 92/234 (39%), Gaps = 50/234 (21%) Query: 167 IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 226 I D+++ A G P+ IPGV +YG ++ FA LP PER Sbjct: 130 ITADHILIATGGRPSHPDIPGV-EYG---------IDSDGFFA--------LP-ALPER- 169 Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 + VVG G GVE G + + HL E L F+ +S Sbjct: 170 ----VAVVGAGYIGVELGGVINGL--------------GAKTHLFEMFDAPLPSFDPMIS 211 Query: 287 SYAQSHLENTSIKVH---LRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKA 343 + ++H + AV K + L + EDG+ ET+ LIWA G + Sbjct: 212 ETLVEVMNAEGPQLHTNAIPKAVVKNTDGSLTLEL--EDGR--SETVD--CLIWAIGRE- 264 Query: 344 RPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFA-GLPPTAQVA 396 P ++ + ++++G V D Q I+A+GDN A L P A A Sbjct: 265 -PANDNINLEAAGVKTNEKGYIVVDKYQNTNIEGIYAVGDNTGAVELTPVAVAA 317 >2HQM-A nrPDB Length = 479 Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 45/116 (38%), Gaps = 19/116 (16%) Query: 231 IVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQ 290 +VVVG G G+E AG L E HLV VL F++ + + Sbjct: 188 VVVVGAGYIGIELAG------------VFHGLGSET--HLVIRGETVLRKFDECIQNTIT 233 Query: 291 SHLENTSIKVHLRTAVAKVEEKQLLAKTK--HEDGKITEETIPYGTLIWATGNKAR 344 H I VH + + KVE+ K K D K ++ LIW G K+ Sbjct: 234 DHYVKEGINVHKLSKIVKVEKNVETDKLKIHMNDSKSIDDV---DELIWTIGRKSH 286 >2YVG-A nrPDB Length = 408 Score = 32.7 bits (73), Expect = 0.43, Method: Compositional matrix adjust. Identities = 51/216 (23%), Positives = 86/216 (39%), Gaps = 40/216 (18%) Query: 49 QHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSII 108 Q + K V++LG+G ++SF+ + Y I VG E+ Sbjct: 3 QEALKAPVVVLGAGLASVSFVAELRQAGYQGLITV---------------VGDEAERPYD 47 Query: 109 EPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIK 168 P ++ K + + +AE ++ R L +Q + P+ H + ++ + Sbjct: 48 RPPLS-----KDFMAHGDAEKIRLDCKRAPEVEWLLGVTAQSFDPQAHT-VALSDGRTLP 101 Query: 169 YDYLISAVGAEPNTF-GIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRR 227 Y L+ A GA P + G T H L+ + ++ I +A L P+ R Sbjct: 102 YGTLVLATGAAPRALPTLQGATMPVHTLRTLEDARRI---------QAGLRPQS-----R 147 Query: 228 LLSIVVVGGGPTGVEAAGELQDY-VHQDLRKFLPAL 262 LL +VGGG G+E A + VH L + P L Sbjct: 148 LL---IVGGGVIGLELAATARTAGVHVSLVETQPRL 180 >1XHC-A nrPDB Length = 367 Score = 31.6 bits (70), Expect = 0.76, Method: Compositional matrix adjust. Identities = 35/117 (29%), Positives = 56/117 (47%), Gaps = 16/117 (13%) Query: 231 IVVVGGGPTGVEAAGEL-QDYVHQDLRKF-LPALAEEVQIHLVEALPIVLNMFEKKLSSY 288 +V+VG GP G E A +L Q Y + K +P ++ + H + +F L Y Sbjct: 11 VVIVGNGPGGFELAKQLSQTYEVTVIDKEPVPYYSKPMLSHYIAGFIPRNRLFPYSLDWY 70 Query: 289 AQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEE-TIPYGTLIWATGNKAR 344 + +E +R A EE +L+ + + ITE+ +PY TL+ ATG +AR Sbjct: 71 RKRGIE-------IRLA----EEAKLIDRGRKV--VITEKGEVPYDTLVLATGARAR 114 >5ER0-A nrPDB Length = 518 Score = 31.6 bits (70), Expect = 0.83, Method: Compositional matrix adjust. Identities = 64/283 (22%), Positives = 102/283 (36%), Gaps = 56/283 (19%) Query: 116 LKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISA 175 L+K G +I+PD+ TVT++ L+ NH A+ E YD L+ Sbjct: 116 LQKLGANVQMNHNVLAIDPDQKTVTVEDLT---------NH-----AQTTE-SYDKLVMT 160 Query: 176 VGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVG 235 G+ P IPG+ R N A L + E +R I V+G Sbjct: 161 SGSWPIVPKIPGID-------------SDRVKLCKNWAHAQALIEDAKEAKR---ITVIG 204 Query: 236 GGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQSHLE 294 G G E A H + L++A+ V+ F+ + + Sbjct: 205 AGYIGAELAEAYSTTGH--------------DVTLIDAMARVMPKYFDADFTDVIEQDYR 250 Query: 295 NTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKI 354 + +++ L V + K + K + ET I G + TDL K Sbjct: 251 DHGVQLALGETVESFTDSATGLTIKTD--KNSYET---DLAILCIGFRPN---TDLLKG- 301 Query: 355 PEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAH 397 + + + G + D + +IFA GD+A PT Q A+ Sbjct: 302 -KVDMAPNGAIITDDYMRSSNPDIFAAGDSAAVHYNPTHQNAY 343 >3ZK8-A nrPDB Length = 278 Score = 31.6 bits (70), Expect = 0.95, Method: Compositional matrix adjust. Identities = 48/171 (28%), Positives = 72/171 (42%), Gaps = 30/171 (17%) Query: 321 EDGKITEET--IPYGTLIWATGNKARPVITDLFKKIPE---QNSSKRGLAVNDFLQVKGS 375 ED K T E I Y + TG A F K+ E + +K AV+D + V Sbjct: 43 EDVKKTSEADLIFYNGINLETGGNA------WFTKLVENAKKTENKDYFAVSDGVDV--- 93 Query: 376 NNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKM--AQIPN----FQKNLSSRKDKIDL 429 I+ G N P A + + AKN K A+ PN ++KNL DK+D Sbjct: 94 --IYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDK 151 Query: 430 LFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRI 480 L +E+ K+N + A ++ I T + + F G+ + Y+W I Sbjct: 152 LDKESK---DKFNKIPA-----EKKLIVTSQGAFKYFSKAYGVPSAYIWEI 194 >3CGD-A nrPDB Length = 480 Score = 31.6 bits (70), Expect = 0.98, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 33/80 (41%), Gaps = 16/80 (20%) Query: 166 EIKYDYLISAVGAEPNTFGIPGVTDYG-HFLKEIPNSLEIRRTFAANLEKANLLPKGDPE 224 E YD L+ A G P G G H LK IP++ I +T N Sbjct: 138 EFSYDRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETN------------- 184 Query: 225 RRRLLSIVVVGGGPTGVEAA 244 ++ + ++GGG G+E A Sbjct: 185 --KVEDVTIIGGGAIGLEMA 202 >3VEW-A nrPDB Length = 576 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 23/41 (56%), Gaps = 6/41 (14%) Query: 438 PFKYNDLGALAYLGSERAIATI------RSGKRTFYTGGGL 472 P++Y DL A A ERA+ + R+G+RT + GG+ Sbjct: 277 PYEYRDLAATAQAALERAVFGLADSVLARTGERTLFVAGGV 317 >1EBD-A nrPDB Length = 455 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 43/176 (24%), Positives = 76/176 (43%), Gaps = 23/176 (13%) Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 S+VV+GGG G+E ++ ++ ++E +L+ FEK++++ Sbjct: 172 SLVVIGGGYIGIELGTAYANF--------------GTKVTILEGAGEILSGFEKQMAAII 217 Query: 290 QSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITD 349 + L+ ++V + A+AK E++ T + +TI ++ G RP + Sbjct: 218 KKRLKKKGVEV-VTNALAKGAEEREDGVTVTYEANGETKTIDADYVLVTVGR--RPNTDE 274 Query: 350 LFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 L + + RGL D NIFAIGD + P +AH+ A Y K Sbjct: 275 LGLEQIGIKMTNRGLIEVDQQCRTSVPNIFAIGD-----IVPGPALAHK-ASYEGK 324 >4UTP-A nrPDB Length = 314 Score = 31.2 bits (69), Expect = 1.2, Method: Compositional matrix adjust. Identities = 48/171 (28%), Positives = 71/171 (41%), Gaps = 30/171 (17%) Query: 321 EDGKITEET--IPYGTLIWATGNKARPVITDLFKKIPE---QNSSKRGLAVNDFLQVKGS 375 ED K T E I Y + TG A F K+ E + +K AV+D + V Sbjct: 74 EDVKKTSEADLIFYNGINLETGGNA------WFTKLVENAKKTENKDYFAVSDGVDV--- 124 Query: 376 NNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKM--AQIPN----FQKNLSSRKDKIDL 429 I+ G N P A + + AKN K A+ PN ++KNL DK+D Sbjct: 125 --IYLEGQNEKGKEDPHAWLNLENGIIFAKNIAKQLSAKDPNNKEFYEKNLKEYTDKLDK 182 Query: 430 LFEENNFKPFKYNDLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRI 480 L +E+ K+N + A ++ I T + F G+ + Y+W I Sbjct: 183 LDKESK---DKFNKIPA-----EKKLIVTSEGAFKYFSKAYGVPSAYIWEI 225 >6BRD-A nrPDB Length = 476 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 12/21 (57%), Positives = 17/21 (80%) Query: 228 LLSIVVVGGGPTGVEAAGELQ 248 + ++VVGGGPTG+ AGEL+ Sbjct: 1 MFDVIVVGGGPTGLMLAGELR 21 >4YRY-B nrPDB Length = 468 Score = 30.4 bits (67), Expect = 1.9, Method: Compositional matrix adjust. Identities = 35/115 (30%), Positives = 49/115 (42%), Gaps = 15/115 (13%) Query: 168 KYDYLISAVGA-EPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 226 +YD + GA P GIPG G + N R NL KA L P+ D R Sbjct: 225 EYDAVFIGTGAGTPKFMGIPGTNLNGVYSA---NEFLTR----VNLMKAYLFPEYDTPIR 277 Query: 227 RLLSIVVVGGGPTGVEAA------GELQDY-VHQDLRKFLPALAEEVQIHLVEAL 274 + V+G G T ++AA G + Y V++ + +PA EE L E + Sbjct: 278 VGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGI 332 >6MO6-A nrPDB Length = 414 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 25/113 (22%), Positives = 42/113 (37%), Gaps = 23/113 (20%) Query: 78 NVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRN 137 NV+I+ P + P+ G S P + V + +A T +NPD+N Sbjct: 30 NVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTASVI---PSGVEWIKARVTELNPDKN 86 Query: 138 TVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTD 190 + H + +I Y YLI A+G + + I G+ + Sbjct: 87 CI--------------------HTDDDEKISYRYLIIALGIQLDYEKIKGLPE 119 >5NLG-A nrPDB Length = 314 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 10/67 (14%) Query: 192 GHFLKEIP--NSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQD 249 G+ LK +P N +E+ R FA LE KGDPER R L +V P ++ Sbjct: 199 GNALKALPKRNHIEVVRKFA-QLE----FAKGDPERGRSLFEGLVADAPKRIDL---WNV 250 Query: 250 YVHQDLR 256 YV Q+++ Sbjct: 251 YVDQEVK 257 >4Z44-A nrPDB Length = 554 Score = 30.0 bits (66), Expect = 2.3, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 11/62 (17%) Query: 215 ANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEAL 274 + L+P+G + + +IV+VGGG G AA L + AL ++ I L+E+ Sbjct: 8 SGLVPRGSHMNKPIKNIVIVGGGTAGWMAASYL-----------VRALQQQANITLIESA 56 Query: 275 PI 276 I Sbjct: 57 AI 58 >5WUG-A nrPDB Length = 955 Score = 30.0 bits (66), Expect = 2.6, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 38/87 (43%), Gaps = 6/87 (6%) Query: 240 GVEAAGELQDYVHQDLRKFL--PALAEEV----QIHLVEALPIVLNMFEKKLSSYAQSHL 293 G GELQ R L PALA E ++ L++A L + ++ Y S Sbjct: 801 GTLTVGELQRCAMNICRFLLNAPALAREPKPVHEVRLIQAAQGDLPIASAGVNVYTLSRS 860 Query: 294 ENTSIKVHLRTAVAKVEEKQLLAKTKH 320 ++ + + TAV KV+E + T H Sbjct: 861 QSAKVLANAETAVVKVQEAGVYTVTAH 887 >5C9S-B nrPDB Length = 572 Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 34/67 (50%), Gaps = 10/67 (14%) Query: 192 GHFLKEIP--NSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQD 249 G+ LK +P N +E+ R FA LE KGDPER R L +V P ++ Sbjct: 449 GNALKALPKRNHIEVVRKFA-QLE----FAKGDPERGRSLFEGLVADAPKRIDL---WNV 500 Query: 250 YVHQDLR 256 YV Q+++ Sbjct: 501 YVDQEVK 507 >4FX9-A nrPDB Length = 453 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 23/39 (58%), Gaps = 1/39 (2%) Query: 168 KYDYLISAVGAEPNTFGIPGVTDYGHFLKEI-PNSLEIR 205 ++DYL+ A GA P I GV G F ++ P++L IR Sbjct: 105 EWDYLVFANGASPQVPAIEGVNLKGVFTADLPPDALAIR 143 >2GMH-A nrPDB Length = 584 Score = 29.6 bits (65), Expect = 3.3, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 3/64 (4%) Query: 230 SIVVVGGGPTGVEAAGELQDYVHQ---DLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 +V+VG GP G+ AA L+ Q DLR L A + H + + FE+ Sbjct: 37 DVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACLDPRAFEELFP 96 Query: 287 SYAQ 290 + + Sbjct: 97 DWKE 100 >5KOX-A nrPDB Length = 476 Score = 29.3 bits (64), Expect = 3.8, Method: Compositional matrix adjust. Identities = 10/21 (47%), Positives = 17/21 (80%) Query: 228 LLSIVVVGGGPTGVEAAGELQ 248 ++ +++ GGGPTG+ AGEL+ Sbjct: 4 MIDVIIAGGGPTGLMLAGELR 24 >3IWA-A nrPDB Length = 472 Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust. Identities = 83/361 (22%), Positives = 130/361 (36%), Gaps = 66/361 (18%) Query: 82 ISPRSYFLFTPLLPSAPVGTVDEKSIIE-PIVNFALKKKGNVTYYEA-EATSINPDRNTV 139 + P++ F L P A V +D+ S I G V+ E+ +AT N R+ Sbjct: 14 LGPKAACRFKRLDPEAHVTMIDQASRISYGGCGIPYYVSGEVSNIESLQATPYNVVRDPE 73 Query: 140 TIKSLSAVSQLYQPENHL-----------GLHQAEPAEIKYDYLISAVGAEPNTFGIPGV 188 + V L + H L E +KYD L+ A+G++ N + G+ Sbjct: 74 FFRINKDVEALVETRAHAIDRAAHTVEIENLRTGERRTLKYDKLVLALGSKANRPPVEGM 133 Query: 189 TDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQ 248 G T NL++A + + V+VGGG G+E A L Sbjct: 134 DLAG-------------VTPVTNLDEAEFVQHA-ISAGEVSKAVIVGGGFIGLEMAVSLA 179 Query: 249 DYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAK 308 D D + LA+++ +P K LS + LE + VH V + Sbjct: 180 DMWGID--TTVVELADQI-------MP---GFTSKSLSQMLRHDLEKNDVVVHTGEKVVR 227 Query: 309 VEEKQLLAKTKHEDGKIT-----EETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRG 363 +E E+GK+ + T+ +I A G T L + + RG Sbjct: 228 LE---------GENGKVARVITDKRTLDADLVILAAGVSPN---TQLARDAGLE-LDPRG 274 Query: 364 LAVNDFLQVKGSNNIFAIGD-----NAFAGLP---PTAQVAHQEAEYLAKNF-DKMAQIP 414 + D +IFA GD N G P P +A+++ + N D A P Sbjct: 275 AIIVDTRMRTSDPDIFAGGDCVTIPNLVTGKPGFFPLGSMANRQGRVIGTNLADGDATFP 334 Query: 415 N 415 Sbjct: 335 G 335 >2BC1-A nrPDB Length = 490 Score = 28.9 bits (63), Expect = 4.9, Method: Compositional matrix adjust. Identities = 42/140 (30%), Positives = 57/140 (40%), Gaps = 34/140 (24%) Query: 116 LKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISA 175 L+ G Y E+ SI+ D TVT L +NH+ YD LI A Sbjct: 102 LESLGAKVYMESPVQSIDYDAKTVT--------ALVDGKNHVE---------TYDKLIFA 144 Query: 176 VGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLE-------KANLLPKGDPERRRL 228 G++P I G +KE SLE T NL+ A+++ K E + + Sbjct: 145 TGSQPILPPIKGAE-----IKE--GSLEFEATLE-NLQFVKLYQNSADVIAK--LENKDI 194 Query: 229 LSIVVVGGGPTGVEAAGELQ 248 + VVG G GVE A Q Sbjct: 195 KRVAVVGAGYIGVELAEAFQ 214 >3FKQ-A nrPDB Length = 373 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 30/117 (25%) Query: 185 IPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAA 244 I G+ +Y + ++P SLEI EK LL K I+VV G Sbjct: 254 IQGMDNYDEIIVDLPFSLEI--------EKLKLLSKA-------WRIIVVNDGS------ 292 Query: 245 GELQDYVHQDLRKFLPALAEEVQIHLVEALPIV--LNMFEKKLSSYAQSHLENTSIK 299 +L +Y KF+ A V + + + I+ +NM K S+ L N SIK Sbjct: 293 -QLSNY------KFMRAYESVVLLEQNDDINIIRNMNMIYNKFSNKNSEMLSNISIK 342 >6IHE-A nrPDB Length = 303 Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust. Identities = 50/212 (23%), Positives = 85/212 (40%), Gaps = 42/212 (19%) Query: 167 IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLE--IRRTFAANLEKANLLPKGDPE 224 I Y L+S E + I + E+P+ E +R FA KAN+L + Sbjct: 15 IAYSALVSGAVDEAVIYDI---------IPELPDKFEHELRHAFATKGIKANVLGTNSLD 65 Query: 225 RRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEV------QIHLVEALPI-- 276 + IVV+ G G + + D K + LA+++ I+L+ A P+ Sbjct: 66 DVSGMDIVVISAGKP--RKPGMSRRDLFVDNAKIMIDLAQKLPSKNPGAIYLMVANPVDM 123 Query: 277 ---VLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYG 333 V + K+ + A +E + +R+ +A K+L DG + E Sbjct: 124 MASVFMKYSKQFTISAGDQVET----MRMRSFIA----KKLKIPVTSVDGFVGGEHGEDA 175 Query: 334 TLIWATGN-KARPV---------ITDLFKKIP 355 ++W+T K +PV ++D KKIP Sbjct: 176 VVLWSTVKIKGKPVDEFNINKDEVSDYVKKIP 207 >2NZW-A nrPDB Length = 371 Score = 28.5 bits (62), Expect = 6.7, Method: Compositional matrix adjust. Identities = 14/32 (43%), Positives = 20/32 (62%) Query: 438 PFKYNDLGALAYLGSERAIATIRSGKRTFYTG 469 P +++DL LGS R I + ++ KR FYTG Sbjct: 63 PNEFSDLVFGNPLGSARKILSYQNAKRVFYTG 94 >1FOH-A nrPDB Length = 664 Score = 28.1 bits (61), Expect = 9.3, Method: Compositional matrix adjust. Identities = 11/25 (44%), Positives = 16/25 (64%) Query: 229 LSIVVVGGGPTGVEAAGELQDYVHQ 253 +++VG GP G+ AA L +YV Q Sbjct: 8 CDVLIVGAGPAGLMAARVLSEYVRQ 32 >5JCN-A nrPDB Length = 451 Score = 28.1 bits (61), Expect = 9.5, Method: Compositional matrix adjust. Identities = 49/233 (21%), Positives = 96/233 (41%), Gaps = 44/233 (18%) Query: 159 LHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLL 218 L A A Y+ LI A G+ + ++D+G + N L +R A+ A + Sbjct: 122 LTSAVGATFTYEILIIATGSS-----VIKLSDFGTQGADSNNILYLREVDDADKLVAAI- 175 Query: 219 PKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL 278 + ++ V+VGGG G+E + L+ + + +V P + Sbjct: 176 -----QAKKGGKAVIVGGGYIGLELSAALK--------------INDFDVTMVFPEPWCM 216 Query: 279 -NMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIW 337 +F ++++ +S+ N +K+ T + +G +T + G+++ Sbjct: 217 PRLFTADIAAFYESYYTNKGVKIVKGTVAVGFD--------ADANGDVTAVNLKNGSVLE 268 Query: 338 A----TGNKARPVITDLFK-KIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 A G RP +T LFK ++ E+ K G+ + F + ++A+GD A Sbjct: 269 ADIVVVGVGGRP-LTTLFKGQVAEE---KGGIKTDAFFETS-VPGVYAVGDVA 316 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4G74-A nrPDB 757 0.0 5JWC-A nrPDB 361 e-100 5NA1-A nrPDB 348 3e-96 3ICS-A nrPDB 198 7e-51 2NVK-X nrPDB 164 8e-41 3OC4-A nrPDB 132 4e-31 3HYW-A nrPDB 117 1e-26 Sequences not found previously or not previously below threshold: 2X8H-A nrPDB 118 6e-27 3NTA-A nrPDB 116 2e-26 4LA1-A nrPDB 111 1e-24 1ZDL-A nrPDB 104 1e-22 3IWA-A nrPDB 100 2e-21 5W1J-A nrPDB 96 4e-20 4KPR-E nrPDB 96 5e-20 2CFY-A nrPDB 95 6e-20 2R9Z-A nrPDB 95 9e-20 1XHC-A nrPDB 90 2e-18 5ER0-A nrPDB 88 7e-18 4B1B-A nrPDB 88 1e-17 3H8L-A nrPDB 86 5e-17 5VDN-A nrPDB 86 5e-17 3CGD-A nrPDB 85 7e-17 5U1O-A nrPDB 84 1e-16 6DU7-A nrPDB 84 2e-16 2CDU-A nrPDB 83 2e-16 1GEU-A nrPDB 83 2e-16 3FG2-P nrPDB 83 4e-16 2BC1-A nrPDB 82 5e-16 3T14-A nrPDB 81 1e-15 2HQM-A nrPDB 81 1e-15 1NHQ-A nrPDB 81 1e-15 1LVL-A nrPDB 80 3e-15 1EBD-A nrPDB 80 3e-15 1YQZ-A nrPDB 79 4e-15 2WOV-A nrPDB 79 5e-15 6CMZ-A nrPDB 77 2e-14 2V3B-A nrPDB 75 6e-14 4NEW-A nrPDB 75 7e-14 6N7F-A nrPDB 71 8e-13 1DXL-A nrPDB 69 3e-12 1FEC-A nrPDB 69 3e-12 2YVG-A nrPDB 69 5e-12 5V36-A nrPDB 69 5e-12 4YWO-A nrPDB 69 6e-12 6B4O-A nrPDB 68 7e-12 3Q6J-A nrPDB 68 7e-12 2AAQ-A nrPDB 68 1e-11 3KLJ-A nrPDB 67 2e-11 2YQU-A nrPDB 64 1e-10 2YAU-A nrPDB 64 1e-10 5X1Y-B nrPDB 64 1e-10 4FX9-A nrPDB 64 1e-10 3O0H-A nrPDB 64 1e-10 3LAD-A nrPDB 64 2e-10 4JDR-A nrPDB 64 2e-10 2QAE-A nrPDB 63 2e-10 3LXD-A nrPDB 63 3e-10 6AON-A nrPDB 63 3e-10 3L8K-A nrPDB 62 5e-10 3URH-A nrPDB 62 5e-10 1Q1R-A nrPDB 61 8e-10 2EQ6-A nrPDB 61 1e-09 5U8W-A nrPDB 61 2e-09 5U25-A nrPDB 59 3e-09 1OJT-A nrPDB 59 3e-09 5TR3-A nrPDB 59 3e-09 6MO6-A nrPDB 59 4e-09 5JCN-A nrPDB 59 5e-09 1XDI-A nrPDB 59 6e-09 6BZ0-A nrPDB 58 8e-09 3II4-A nrPDB 58 1e-08 1ONF-A nrPDB 56 4e-08 5J5Z-A nrPDB 56 5e-08 4DNA-A nrPDB 54 2e-07 4EMJ-A nrPDB 53 3e-07 1V59-A nrPDB 53 4e-07 5KVH-A nrPDB 52 6e-07 4YRY-B nrPDB 50 2e-06 3F8P-A nrPDB 49 4e-06 5VJ7-A nrPDB 49 5e-06 1ZK7-A nrPDB 46 3e-05 1FL2-A nrPDB 45 1e-04 4YKF-A nrPDB 44 2e-04 5JFC-L nrPDB 43 3e-04 1F6M-A nrPDB 40 0.002 2VDC-G nrPDB 40 0.002 5M5J-A nrPDB 38 0.012 3IC9-A nrPDB 37 0.017 5UWY-A nrPDB 35 0.075 5N1T-A nrPDB 34 0.13 5U63-A nrPDB 34 0.17 6BWT-A nrPDB 33 0.29 1FCD-A nrPDB 33 0.46 6GAS-A nrPDB 33 0.49 3VEW-A nrPDB 33 0.51 4C7Y-A nrPDB 32 0.78 4GCM-A nrPDB 32 0.81 3EJX-A nrPDB 31 0.92 5GY2-A nrPDB 31 0.97 3D8X-A nrPDB 31 1.1 2Q7V-A nrPDB 31 1.2 4QI7-A nrPDB 31 1.2 4NTC-A nrPDB 31 1.3 5L3D-A nrPDB 31 1.5 3ABT-A nrPDB 31 1.5 5MJK-A nrPDB 31 1.5 4CBQ-A nrPDB 31 1.6 6GAR-A nrPDB 31 1.7 4ZN0-A nrPDB 30 2.6 4QI6-A nrPDB 30 2.8 4QI5-A nrPDB 30 2.8 5XK2-A nrPDB 29 3.6 3LZX-A nrPDB 29 4.0 1QO8-A nrPDB 29 4.1 3DV8-A nrPDB 29 4.5 4Y4M-A nrPDB 29 5.8 6BPY-A nrPDB 29 6.1 5ZYN-B nrPDB 29 6.5 1VDC-A nrPDB 28 7.9 >4G74-A nrPDB Length = 502 Score = 757 bits (1953), Expect = 0.0, Method: Composition-based stats. Identities = 490/491 (99%), Positives = 491/491 (100%) Query: 23 ASTRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSII 82 +STRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSII Sbjct: 12 SSTRSTGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSII 71 Query: 83 SPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIK 142 SPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIK Sbjct: 72 SPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIK 131 Query: 143 SLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL 202 SLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL Sbjct: 132 SLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSL 191 Query: 203 EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPAL 262 EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPAL Sbjct: 192 EIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPAL 251 Query: 263 AEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHED 322 AEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHED Sbjct: 252 AEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHED 311 Query: 323 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG 382 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG Sbjct: 312 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG 371 Query: 383 DNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYN 442 DNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYN Sbjct: 372 DNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYN 431 Query: 443 DLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKL 502 DLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKL Sbjct: 432 DLGALAYLGSERAIATIRSGKRTFYTGGGLMTFYLWRILYLSMILSARSRLKVFFDWIKL 491 Query: 503 AFFKRDFFKGL 513 AFFKRDFFKGL Sbjct: 492 AFFKRDFFKGL 502 >5JWC-A nrPDB Length = 521 Score = 361 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 155/522 (29%), Positives = 248/522 (47%), Gaps = 91/522 (17%) Query: 53 KPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIV 112 K ++ILGSGWG +FL +ID KKY+V++ISPR+YF FTPLLP GT+ E I Sbjct: 28 KEKIIILGSGWGGFNFLLNIDFKKYDVTLISPRNYFTFTPLLPCLCSGTLSVNVCTESIR 87 Query: 113 NFALKKKGNV-TYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIK--Y 169 NF KK G Y + E T + + + ++ E ++K Y Sbjct: 88 NFLRKKNGYCGNYLQLECTDV------------------FYEDKYINCIDIENNKVKLFY 129 Query: 170 DYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 DYLI AVGA+ NTF I GV Y +F+K+I ++L+IR+ F LEK L + E++++L Sbjct: 130 DYLIIAVGAKTNTFNINGVDKYAYFVKDIDDALKIRKKFLDILEKCTLPNISNEEKKKML 189 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 + VVGGGPTGVE E D+++++++ + + I ++E +L F + +S + Sbjct: 190 HVAVVGGGPTGVEVTAEFADFINKEVKINYKDIFNFISISIIEGGNNLLPTFTQNISDFT 249 Query: 290 QSHLENTSIKVHLRTAVAKVEEKQLLAKT---KHEDGKITEETIPYGTLIWATGNKARPV 346 + + N +I V V V++ ++ K+E K++ YG LIWA+G + Sbjct: 250 KENFHNLNINVLTNYYVIDVDKHSFHIQSSLNKNEKKKLS-----YGLLIWASGLAQTTL 304 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKG--SNNIFAIGDN-----------------AFA 387 I K IP Q ++ L V++ L+V G SNNI+AIGD Sbjct: 305 IQKFLKTIPVQ-ANNAILKVDEKLRVIGIPSNNIYAIGDCKKIQPKLLHEHTNEIIKILT 363 Query: 388 GLPPTAQVAHQEAEYLAKNFDKMA----QIPNFQKNLSSRKDKIDLLFE----------- 432 G T++ + L K F +++ +K + + D LFE Sbjct: 364 GNKLTSEALKLKQSELTKTFPQLSISKWDYEKNKKGEMTPQQFHDYLFEIDKNYKSPTPT 423 Query: 433 -----------ENNFKPFKYND------------LGALAYLGSERAIATIRSGKRTFYTG 469 N F F + + G+LAY+G+ + +A + + Sbjct: 424 AQNAKQEAYYLSNVFNNFIHTNQKFNIPSFIEKWKGSLAYIGNHQVVADL----PYYELK 479 Query: 470 GGLMTFYLWRILYLSMILSARSRLKVFFDWIKLAFFKRDFFK 511 GG + W+++Y+ ++LS +SR F D+IK ++ R F K Sbjct: 480 GGRFSSTFWKVVYIQLLLSWKSRFHFFIDFIKTKWYGRPFIK 521 >5NA1-A nrPDB Length = 408 Score = 348 bits (892), Expect = 3e-96, Method: Composition-based stats. Identities = 108/419 (25%), Positives = 188/419 (44%), Gaps = 68/419 (16%) Query: 52 DKPNVLILGSGWGAISFL----KHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSI 107 D+ VL+LG+G+ + + K I T++ +++I+ Y L A GT++ + + Sbjct: 10 DRKKVLVLGAGYAGLQTVTKLQKAISTEEAEITLINKNEYHYEATWLHEASAGTLNYEDV 69 Query: 108 IEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEI 167 + P+ ++ KK V + +AE T I+ D V E + G++ Sbjct: 70 LYPVE--SVLKKDKVNFVQAEVTKIDRDAKKV--------------ETNQGIYD------ 107 Query: 168 KYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRR 227 +D L+ A+G TFGI G+ D+ ++ + + E+ R K + Sbjct: 108 -FDILVVALGFVSETFGIEGMKDHAFQIENVITARELSRHIED---KFANYAASKEKDDN 163 Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 LSI+V G G TGVE GEL D + + K+ +V+I VEA P +L MF ++L + Sbjct: 164 DLSILVGGAGFTGVEFLGELTDRIPELCSKY-GVDQNKVKITCVEAAPKMLPMFSEELVN 222 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 +A S+LE+ ++ + T + EK + + E ++ + GT +WA G + ++ Sbjct: 223 HAVSYLEDRGVEFKIATPIVACNEKGFVVEVDGE-----KQQLNAGTSVWAAGVRGSKLM 277 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDN---AFAG----LPPTAQVAHQEA 400 + F+ + + + L + G +NIF IGD AG LP TAQ+A Q+ Sbjct: 278 EESFEGVK-----RGRIVTKQDLTINGYDNIFVIGDCSAFIPAGEERPLPTTAQIAMQQG 332 Query: 401 EYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATI 459 E +AKN I + + + F+Y D G + LGS + + Sbjct: 333 ESVAKN--------------------IKRILNGESTEEFEYVDRGTVCSLGSHDGVGMV 371 >3ICS-A nrPDB Length = 588 Score = 198 bits (502), Expect = 7e-51, Method: Composition-based stats. Identities = 68/343 (19%), Positives = 132/343 (38%), Gaps = 66/343 (19%) Query: 74 TKKYNVSIISPRSYFLFTPL-LPSAPVGTVDEKSIIEPIVNFALKKKGNVTY-YEAEATS 131 +++ + ++ Y F LP G + E+ + + K+ N+ +E Sbjct: 59 SEEDEIIMVERGEYISFANCGLPYYIGGVITERQKLLVQTVERMSKRFNLDIRVLSEVVK 118 Query: 132 INPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDY 191 IN + T+TIK+++ ++ Y YD LI + GA+P IPG+ + Sbjct: 119 INKEEKTITIKNVTT-NETYNE--------------AYDVLILSPGAKPIVPSIPGIEEA 163 Query: 192 G--HFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQD 249 L+ +P++ I+ + ++ V+GGG GVE L++ Sbjct: 164 KALFTLRNVPDTDRIKAYI---------------DEKKPRHATVIGGGFIGVEMVENLRE 208 Query: 250 YVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKV 309 +++ LVE V+ + ++++Y H++N +++ V + Sbjct: 209 --------------RGIEVTLVEMANQVMPPIDYEMAAYVHEHMKNHDVELVFEDGVDAL 254 Query: 310 EEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDF 369 EE + + K + I LI A G + + L K + + VN+ Sbjct: 255 EENGAVVRLK------SGSVIQTDMLILAIGVQPE---SSLAKGAGLALGVRGTIKVNEK 305 Query: 370 LQVKGSNNIFAIGDNAFA--------GLPPTAQVAHQEAEYLA 404 Q +I+AIGD + P A A+++ LA Sbjct: 306 FQTS-DPHIYAIGDAIEVKDFVTETETMIPLAWPANRQGRMLA 347 >2NVK-X nrPDB Length = 488 Score = 164 bits (415), Expect = 8e-41, Method: Composition-based stats. Identities = 75/338 (22%), Positives = 124/338 (36%), Gaps = 77/338 (22%) Query: 129 ATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGV 188 T ++ V + + L ++ I + AVG P IPG Sbjct: 113 VTRVDLRDKKVEYING--LGSFVDSHTLLAKLKSGERTITAQTFVIAVGGRPRYPDIPGA 170 Query: 189 TDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQ 248 +YG ++ F+ + E L VVG G G+E AG Sbjct: 171 VEYGITSDDL---------FSLDREPGKTL--------------VVGAGYIGLECAG--- 204 Query: 249 DYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRT---A 305 FL L E + + IVL F+++++ + +E I +T + Sbjct: 205 ---------FLKGLGYEPTVMVRS---IVLRGFDQQMAELVAASMEERGIPFLRKTVPLS 252 Query: 306 VAKVEEKQLLAKTKH-EDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGL 364 V K ++ +LL K K+ E G+ +E+ Y T++WA G K ++ DL N G+ Sbjct: 253 VEKQDDGKLLVKYKNVETGEESEDV--YDTVLWAIGRKG--LVDDL-------NLPNAGV 301 Query: 365 AVN------DFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQK 418 V D + NI+A+GD + G P VA LA+ + K Sbjct: 302 TVQKDKIPVDSQEATNVANIYAVGDIIY-GKPELTPVAVLAGRLLARRLYGGSTQRMDYK 360 Query: 419 NLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAI 456 ++++ F P +Y +G L E A+ Sbjct: 361 DVATTV-----------FTPLEYACVG----LSEEDAV 383 >3OC4-A nrPDB Length = 452 Score = 132 bits (331), Expect = 4e-31, Method: Composition-based stats. Identities = 71/369 (19%), Positives = 138/369 (37%), Gaps = 73/369 (19%) Query: 55 NVLILGSGWGAISFLKHIDTK--KYNVSIISPRSYFLF-TPLLPSAPVGTVDEKSIIEPI 111 ++I+G+ + IS K + +S+I ++ + + L + T++E I Sbjct: 4 KIVIIGASFAGISAAIASRKKYPQAEISLIDKQATVGYLSGGLSAYFNHTINELHEARYI 63 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 L+++ E +++ + + + E YD Sbjct: 64 TEEELRRQKIQLLLNREVVAMDVENQLIAWTR-----------------KEEQQWYSYDK 106 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 LI A GA + + ++ ++ F + P ++ Sbjct: 107 LILATGA----------SQFSTQIRGSQTEKLLKYKFLSG------ALAAVPLLENSQTV 150 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN-MFEKKLSSYAQ 290 V+G GP G+EA FL + + +H+ E+L +L F+K++ + Q Sbjct: 151 AVIGAGPIGMEAI------------DFLVKMKK--TVHVFESLENLLPKYFDKEMVAEVQ 196 Query: 291 SHLENTSIKVHLRTAVAKVEE--KQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVIT 348 LE ++ H V +EE ++ +T +E+ I + I+A P + Sbjct: 197 KSLEKQAVIFHFEETVLGIEETANGIVLET-------SEQEISCDSGIFAL--NLHPQLA 247 Query: 349 DLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQV--------AHQEA 400 L KKI Q + + +AV+ +LQ N+FAIGD P A+ A + Sbjct: 248 YLDKKI--QRNLDQTIAVDAYLQTS-VPNVFAIGDCISVMNEPVAETFYAPLVNNAVRTG 304 Query: 401 EYLAKNFDK 409 +A N ++ Sbjct: 305 LVVANNLEE 313 >2X8H-A nrPDB Length = 598 Score = 118 bits (295), Expect = 6e-27, Method: Composition-based stats. Identities = 74/351 (21%), Positives = 121/351 (34%), Gaps = 87/351 (24%) Query: 117 KKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAV 176 + VTY A+ I+P +T K+ + +I A Sbjct: 216 LRDNQVTYLNAKGRLISPHEVQITDKNQKVSTITGNK------------------IILAT 257 Query: 177 GAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGG 236 G P IPG +YG ++ F+ L V+G Sbjct: 258 GERPKYPEIPGAVEYGITSDDL---------FSLPYFPGKTL--------------VIGA 294 Query: 237 GPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENT 296 +E AG FL +L +V + + I+L F+++++ ++EN Sbjct: 295 SYVALECAG------------FLASLGGDVTVMVRS---ILLRGFDQQMAEKVGDYMENH 339 Query: 297 SIKV--------HLRTAVAKVEEKQ---LLAKTKHEDGKITEETIPYGTLIWATGNKARP 345 +K + V E + LL K + DGK EE + T+I+A G + + Sbjct: 340 GVKFAKLCVPDEIKQLKVVDTENNKPGLLLVKGHYTDGKKFEEE--FETVIFAVGREPQ- 396 Query: 346 VITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 + L + + + + D Q +N++AIGD AG P VA Q YLA+ Sbjct: 397 LSKVLCETVGVKLDKNGRVVCTDDEQTT-VSNVYAIGD-INAGKPQLTPVAIQAGRYLAR 454 Query: 406 NFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAI 456 A N+++ F P +Y L E AI Sbjct: 455 RLFAGATELTDYSNVATTV-----------FTPLEY----GACGLSEEDAI 490 >3HYW-A nrPDB Length = 430 Score = 117 bits (293), Expect = 1e-26, Method: Composition-based stats. Identities = 70/328 (21%), Positives = 123/328 (37%), Gaps = 54/328 (16%) Query: 79 VSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNT 138 +++IS R YF FTP P +G + I P+ L K N+ + +A SI+PD NT Sbjct: 30 ITLISDRPYFGFTPAFPHLAMGWRKFEDISVPLA--PLLPKFNIEFINEKAESIDPDANT 87 Query: 139 VTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEI 198 VT +S +I+YDYL+ A G + FG G + + Sbjct: 88 VTTQSGK--------------------KIEYDYLVIATGPK-LVFGAEGQEENSTSICTA 126 Query: 199 PNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAG---ELQDYVHQDL 255 ++LE ++ E VV+G P GV G E +H +L Sbjct: 127 EHALETQKKL--------------QELYANPGPVVIGAIP-GVSCFGPAYEFALMLHYEL 171 Query: 256 RKFLPALAEEVQIHLVEALPIVLNMFEKKLSS---YAQSHLENTSIKVHLRTAVAKVEEK 312 +K + +V + + + P + + + + + +I AV +E Sbjct: 172 KK--RGIRYKVPMTFITSEPYLGHFGVGGIGASKRLVEDLFAERNIDWIANVAVKAIEPD 229 Query: 313 QLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQV 372 +++ +ED +P ++ + V+ K+ N + + + VN Q Sbjct: 230 KVI----YEDLNGNTHEVPAKFTMFMPSFQGPEVVASAGDKV--ANPANKMVIVNRCFQN 283 Query: 373 KGSNNIFAIGDNAFAGLPPTAQVAHQEA 400 NIF +G +PP + Sbjct: 284 PTYKNIFGVG--VVTAIPPIEKTPIPTG 309 >3NTA-A nrPDB Length = 574 Score = 116 bits (291), Expect = 2e-26, Method: Composition-based stats. Identities = 72/360 (20%), Positives = 124/360 (34%), Gaps = 74/360 (20%) Query: 74 TKKYNVSIISPRSYFLFTPL-LPSAPVGTVDEKSIIEPIVNFALKKKGNVTY-YEAEATS 131 ++ + + Y F LP G + ++S + + K + NV + E + Sbjct: 24 SETAEIIMFERGEYVSFANCGLPYHISGEIAQRSALVLQTPESFKARFNVEVRVKHEVVA 83 Query: 132 INPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTD- 190 I+ VT++ L S+ YQ YD L+ + GA P IPGV + Sbjct: 84 IDRAAKLVTVRRLLDGSE-YQE--------------SYDTLLLSPGAAPIVPPIPGVDNP 128 Query: 191 YGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDY 250 H L+ IP+ I +T N + VVGGG G+E L Sbjct: 129 LTHSLRNIPDMDRILQTIQMN---------------NVEHATVVGGGFIGLEMMESLHHL 173 Query: 251 VHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKV- 309 ++ L+E V+ +++++ +A + + + + L TA+++V Sbjct: 174 --------------GIKTTLLELADQVMTPVDREMAGFAHQAIRDQGVDLRLGTALSEVS 219 Query: 310 --------------EEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIP 355 + K E + LI A G + L + Sbjct: 220 YQVQTHVASDAAGEDTAHQHIKGHLSLTLSNGELLETDLLIMAIGVRPETQ---LARDAG 276 Query: 356 EQNSSKRGLAVNDFLQVKGSNNIFAIGDNA--------FAGLPPTAQVAHQEAEYLAKNF 407 G+ VN +Q I+A+GD A L P A A+++ A N Sbjct: 277 LAIGELGGIKVNAMMQTS-DPAIYAVGDAVEEQDFVTGQACLVPLAGPANRQGRMAADNM 335 >4LA1-A nrPDB Length = 602 Score = 111 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 68/350 (19%), Positives = 112/350 (32%), Gaps = 85/350 (24%) Query: 117 KKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAV 176 + VTY A ++P +T K+ + +I A Sbjct: 222 LRDNAVTYLNARGMLLSPHEVQITEKNKKVSTITGNK------------------IILAT 263 Query: 177 GAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGG 236 G P IPG +YG ++ F+ L VVG Sbjct: 264 GERPKYPEIPGAIEYGITSDDL---------FSLPYFPGKTL--------------VVGA 300 Query: 237 GPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENT 296 ++ AG FL +L +V + + I+L F+++++ ++EN Sbjct: 301 SYVALKCAG------------FLASLGGDVTVMVRS---ILLRGFDQQMAEKVGDYMENH 345 Query: 297 SIKVHL---------RTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 +K V K L K + + T+I+A G P + Sbjct: 346 GVKFAKLCVPDEITQLKPVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGR--EPQL 403 Query: 348 TDLF-KKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKN 406 + L + + + + +D Q +NI+AIGD AG P VA YLA+ Sbjct: 404 SKLNCEAVGVKLDKNGRVVCSDDEQTT-VSNIYAIGD-INAGKPQLTPVAIHAGRYLARR 461 Query: 407 FDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAI 456 A N+++ F P +Y L E AI Sbjct: 462 LFAGATELTDYSNVATTV-----------FTPLEY----GACGLSEEDAI 496 >1ZDL-A nrPDB Length = 517 Score = 104 bits (258), Expect = 1e-22, Method: Composition-based stats. Identities = 58/293 (19%), Positives = 102/293 (34%), Gaps = 60/293 (20%) Query: 170 DYLISAVGAEPNTFG-IPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRL 228 ++++ A G P + G +YG +I F L Sbjct: 175 EHIVIATGGRPRYPTQVKGALEYGITSDDI---------FWLKESPGKTL---------- 215 Query: 229 LSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSY 288 VVG +E AG FL + + + + I L F++++SS Sbjct: 216 ----VVGASYVALECAG------------FLTGIGLDTTVMMRS---IPLRGFDQQMSSL 256 Query: 289 AQSHLENTSIKVH---LRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARP 345 H+E+ + + + + K+ QL T + E+T + T++WA G Sbjct: 257 VTEHMESHGTQFLKGCVPSHIKKLPTNQLQV-TWEDHASGKEDTGTFDTVLWAIGRVPET 315 Query: 346 VITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 +L K N + + V+ + +I+AIGD A G P A + + LA+ Sbjct: 316 RTLNLEKAGISTNPKNQKIIVDA-QEATSVPHIYAIGDVA-EGRPELTPTAIKAGKLLAQ 373 Query: 406 NFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAIAT 458 + N+ + F P +Y +G L E A+A Sbjct: 374 RLFGKSSTLMDYSNVPTTV-----------FTPLEYGCVG----LSEEEAVAL 411 >3IWA-A nrPDB Length = 472 Score = 100 bits (248), Expect = 2e-21, Method: Composition-based stats. Identities = 61/315 (19%), Positives = 111/315 (35%), Gaps = 65/315 (20%) Query: 104 EKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAE 163 + +P F K E A +I+ +TV I++L E Sbjct: 66 YNVVRDP--EFFRINKDVEALVETRAHAIDRAAHTVEIENLRT---------------GE 108 Query: 164 PAEIKYDYLISAVGAEPNTFGIPGVTDYGHF-LKEIPNSLEIRRTFAANLEKANLLPKGD 222 +KYD L+ A+G++ N + G+ G + + + ++ +A Sbjct: 109 RRTLKYDKLVLALGSKANRPPVEGMDLAGVTPVTNLDEAEFVQHAISAG----------- 157 Query: 223 PERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFE 282 + V+VGGG G+E A L D + +VE ++ F Sbjct: 158 ----EVSKAVIVGGGFIGLEMAVSLADMW-------------GIDTTVVELADQIMPGFT 200 Query: 283 -KKLSSYAQSHLENTSIKVHLRTAVAKVE-EKQLLAKTKHEDGKITEETIPYGTLIWATG 340 K LS + LE + VH V ++E E +A+ + + T+ +I A G Sbjct: 201 SKSLSQMLRHDLEKNDVVVHTGEKVVRLEGENGKVARVITD-----KRTLDADLVILAAG 255 Query: 341 NKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFA-----GLP---PT 392 L + + + + V+ ++ +IFA GD G P P Sbjct: 256 VSPNTQ---LARDAGLELDPRGAIIVDTRMRTS-DPDIFAGGDCVTIPNLVTGKPGFFPL 311 Query: 393 AQVAHQEAEYLAKNF 407 +A+++ + N Sbjct: 312 GSMANRQGRVIGTNL 326 >5W1J-A nrPDB Length = 584 Score = 95.7 bits (236), Expect = 4e-20, Method: Composition-based stats. Identities = 60/304 (19%), Positives = 100/304 (32%), Gaps = 81/304 (26%) Query: 119 KGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGA 178 NV Y A ++P T K + +I A G Sbjct: 212 NANVKYLNALGEIVDPHTIKTTNKQGIVKNITTNT------------------IIVATGE 253 Query: 179 EPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGP 238 P IPG +YG ++ F + L VG Sbjct: 254 RPRYPPIPGAKEYGITSDDL---------FTLDHNPGKTL--------------CVGASY 290 Query: 239 TGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSI 298 +E AG FL ++ +V + + I L F+++++ ++ + Sbjct: 291 VSLECAG------------FLSSIGCDVTVMVRS---IFLRGFDQQMAGLISDYIAKYGV 335 Query: 299 KVHL---RTAVAKVEEKQ--------LLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 K T+V +EE + KHEDG ++T T+++A G Sbjct: 336 KFVRPCVPTSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFN--TVLFAVGRDPCT-- 391 Query: 348 TDLFKKIPEQN----SSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYL 403 I QN ++ + V+D + NI+AIGD + AG +A Q + L Sbjct: 392 ----TNIGLQNVDVKTTNGRVVVDDEERT-NVPNIYAIGDVSNAGY-QLTPLAIQAGKNL 445 Query: 404 AKNF 407 A+ Sbjct: 446 ARRL 449 >4KPR-E nrPDB Length = 499 Score = 95.7 bits (236), Expect = 5e-20, Method: Composition-based stats. Identities = 58/290 (20%), Positives = 97/290 (33%), Gaps = 60/290 (20%) Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 + A G P GIPG +Y ++ F+ L Sbjct: 157 FLIATGERPRYLGIPGDKEYCISSDDL---------FSLPYCPGKTL------------- 194 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 291 VVG +E AG FL + +V + + I+L F++ +++ Sbjct: 195 -VVGASYVALECAG------------FLAGIGLDVTVMVRS---ILLRGFDQDMANKIGE 238 Query: 292 HLENTSIKVHLRTAVAKVE--EKQLLAKTK-HEDGKITEETI--PYGTLIWATGNKARPV 346 H+E IK + K+E E + K +EETI + T++ A G + Sbjct: 239 HMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSCTR 298 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKN 406 L + + + + K G + I+AIGD G VA Q LA+ Sbjct: 299 TIGL-ETVGVKINEKTGKIPVTDEEQTNVPYIYAIGD-ILEGKLELTPVAIQAGRLLAQR 356 Query: 407 FDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAI 456 + + N+ + F P +Y L E+A+ Sbjct: 357 LYGGSTVKCDYDNVPTTV-----------FTPLEY----GCCGLSEEKAV 391 >2CFY-A nrPDB Length = 521 Score = 95.3 bits (235), Expect = 6e-20, Method: Composition-based stats. Identities = 57/290 (19%), Positives = 94/290 (32%), Gaps = 60/290 (20%) Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 + A G P GIPG +Y ++ F+ L Sbjct: 179 FLIATGERPRYLGIPGDKEYCISSDDL---------FSLPYCPGKTL------------- 216 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 291 VVG +E AG FL + +V + + I+L F++ +++ Sbjct: 217 -VVGASYVALECAG------------FLAGIGLDVTVMVRS---ILLRGFDQDMANKIGE 260 Query: 292 HLENTSIKVHLRTAVAKVE--EKQLLAKTKHEDGKITEETI---PYGTLIWATGNKARPV 346 H+E IK + KVE E + + E I Y T++ A G A Sbjct: 261 HMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDACTR 320 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKN 406 L + + + + K G + I+AIGD VA Q LA+ Sbjct: 321 KIGL-ETVGVKINEKTGKIPVTDEEQTNVPYIYAIGD-ILEDKVELTPVAIQAGRLLAQR 378 Query: 407 FDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAI 456 + + +N+ + F P +Y L E+A+ Sbjct: 379 LYAGSTVKCDYENVPTTV-----------FTPLEY----GACGLSEEKAV 413 >2R9Z-A nrPDB Length = 463 Score = 94.5 bits (233), Expect = 9e-20, Method: Composition-based stats. Identities = 44/248 (17%), Positives = 82/248 (33%), Gaps = 45/248 (18%) Query: 160 HQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLP 219 + E + D+++ A G P +PG E Sbjct: 122 IEVEGQRLSADHIVIATGGRPIVPRLPGA------------------------ELGITSD 157 Query: 220 KGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN 279 +++ + ++G G G+E AG L+ + ++ +V +L Sbjct: 158 GFFALQQQPKRVAIIGAGYIGIELAGLLRSF--------------GSEVTVVALEDRLLF 203 Query: 280 MFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWAT 339 F+ LS+ ++ I+ HL AVA +E +DG E + ++IWA Sbjct: 204 QFDPLLSATLAENMHAQGIETHLEFAVAALERDAQGTTLVAQDGTRLE---GFDSVIWAV 260 Query: 340 GNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQE 399 G + + S + + + Q ++A+GD G VA Sbjct: 261 GRAPNTR-DLGLEAAGIEVQSNGMVPTDAY-QNTNVPGVYALGDI--TGRDQLTPVAIAA 316 Query: 400 AEYLAKNF 407 LA+ Sbjct: 317 GRRLAERL 324 Score = 29.0 bits (63), Expect = 5.3, Method: Composition-based stats. Identities = 30/146 (20%), Positives = 52/146 (35%), Gaps = 34/146 (23%) Query: 54 PNVLILGSGWGAISFLKHIDTKKYNVSIIS--PRSYFLFTPLLPSAPVGTVDEKSIIEPI 111 V I+G+G+ I + + V++++ R F F PLL T+ E + I Sbjct: 167 KRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLL----SATLAENMHAQGI 222 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 T+ E ++ D T+ + Q +D Sbjct: 223 E----------THLEFAVAALERDAQGTTL-----------------VAQDGTRLEGFDS 255 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKE 197 +I AVG PNT + G+ G ++ Sbjct: 256 VIWAVGRAPNTRDL-GLEAAGIEVQS 280 >1XHC-A nrPDB Length = 367 Score = 89.9 bits (221), Expect = 2e-18, Method: Composition-based stats. Identities = 78/409 (19%), Positives = 148/409 (36%), Gaps = 75/409 (18%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFT-PLLPSAPVGTVDEKSIIEPIVN 113 V+I+G+G G K + + Y V++I ++ P+L G + + P Sbjct: 10 KVVIVGNGPGGFELAKQLS-QTYEVTVIDKEPVPYYSKPMLSHYIAGFIPRNR-LFPYSL 67 Query: 114 FALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLI 173 +K+G EA I+ R V E E+ YD L+ Sbjct: 68 DWYRKRGIEIRLAEEAKLIDRGRKVVIT---------------------EKGEVPYDTLV 106 Query: 174 SAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVV 233 A GA I G +Y L+ I ++ I+ + + E + Sbjct: 107 LATGARAREPQIKG-KEYLLTLRTIFDADRIKESIENSGEAIIIGGGFIG---------- 155 Query: 234 VGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHL 293 +E AG L + + A+ + +++LS+ + L Sbjct: 156 -------LELAGNLAEAGYHVKLIHRGAMFLGL---------------DEELSNMIKDML 193 Query: 294 ENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKK 353 E T +K L + + + E+ +L + +GK+ I A G DL ++ Sbjct: 194 EETGVKFFLNSELLEANEEGVLTNSGFIEGKVK---------ICAIGIVPNV---DLARR 241 Query: 354 IPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA-FAG-LPPTAQVAHQEAEYLAKNFDKMA 411 RG+ ++D + + ++AIGD A ++G + TA+ A ++A LA Sbjct: 242 SGIHTG--RGILIDDNFRTSAKD-VYAIGDCAEYSGIIAGTAKAAMEQARVLADILKGEP 298 Query: 412 QIPNFQKNLSSRK-DKIDLLFEENNFKPFKYNDLGALAYLGSERAIATI 459 + NF+ + K K+ + N K+ + + + + I + Sbjct: 299 RRYNFKFRSTVFKFGKLQIAIIGNTKGEGKWIEDNTKVFYENGKIIGAV 347 >5ER0-A nrPDB Length = 518 Score = 88.4 bits (217), Expect = 7e-18, Method: Composition-based stats. Identities = 72/413 (17%), Positives = 133/413 (32%), Gaps = 87/413 (21%) Query: 27 STGVENSGAGPTSFKTMKVIDPQHSDKP-----------------NVLILGSGWGAISFL 69 S+G+ G+G K + QH D P V ++G + Sbjct: 8 SSGLVPRGSGMKETAAAK-FERQHMDSPDLGTDDDDKAMADIGSMKVTVVGCTHAGTFAI 66 Query: 70 KHIDTK--KYNVSIISPRSYFLFTPLLPSAPVG--TVDEKSIIEPIVNFALKKKGNVTYY 125 K I + V++ F + +G D + + K NV Sbjct: 67 KQILAEHPDAEVTVYERNDVISFLSCGIALYLGGKVADPQGLFYSSPEELQKLGANVQ-M 125 Query: 126 EAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGI 185 +I+PD+ TVT++ L+ +Q + YD L+ G+ P I Sbjct: 126 NHNVLAIDPDQKTVTVEDLTNHAQTTE---------------SYDKLVMTSGSWPIVPKI 170 Query: 186 PGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAG 245 PG+ + +++ + +A + + I V+G G G E A Sbjct: 171 PGIDS---------DRVKLCKNWAHAQ-------ALIEDAKEAKRITVIGAGYIGAELAE 214 Query: 246 ELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN-MFEKKLSSYAQSHLENTSIKVHLRT 304 H + L++A+ V+ F+ + + + +++ L Sbjct: 215 AYSTTGHD--------------VTLIDAMARVMPKYFDADFTDVIEQDYRDHGVQLALGE 260 Query: 305 AVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGL 364 V + K + + I G + TDL K + + Sbjct: 261 TVESFTDSA-----TGLTIKTDKNSYETDLAILCIGFRPN---TDLLKG-KVDMAPNGAI 311 Query: 365 AVNDFLQVKGSNNIFAIGDNAFAG-LP-------PTAQVAHQEAEYLAKNFDK 409 +D+++ +IFA GD+A P P A A ++ + KN K Sbjct: 312 ITDDYMRSSN-PDIFAAGDSAAVHYNPTHQNAYIPLATNAVRQGILVGKNLVK 363 >4B1B-A nrPDB Length = 542 Score = 88.0 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 50/244 (20%), Positives = 94/244 (38%), Gaps = 53/244 (21%) Query: 171 YLISAVGAEPNTFG-IPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 Y++ A G P+ + G + +I F+ + L Sbjct: 188 YILIATGCRPHIPDDVEGAKELSITSDDI---------FSLKKDPGKTL----------- 227 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 VVG +E +G FL +L +V + + IVL F+++ + Sbjct: 228 ---VVGASYVALECSG------------FLNSLGYDVTVAVRS---IVLRGFDQQCAVKV 269 Query: 290 QSHLENTSIKVH---LRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPV 346 + ++E + L + K+++K +L + + ++ Y T+++A G K Sbjct: 270 KLYMEEQGVMFKNGILPKKLTKMDDK-ILVEFSDKTSEL------YDTVLYAIGRKGDID 322 Query: 347 ITDLFK-KIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 +L + S+ + +A D L +IFA+GD A +P A VA + E LA+ Sbjct: 323 GLNLESLNMNVNKSNNKIIA--DHLSCTNIPSIFAVGDVA-ENVPELAPVAIKAGEILAR 379 Query: 406 NFDK 409 K Sbjct: 380 RLFK 383 >3H8L-A nrPDB Length = 409 Score = 85.7 bits (210), Expect = 5e-17, Method: Composition-based stats. Identities = 60/369 (16%), Positives = 124/369 (33%), Gaps = 40/369 (10%) Query: 55 NVLILGSGWGAIS---FLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPI 111 VL+LG +GA++ LK + K +V +I+ + F P LP +G D + + Sbjct: 3 KVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVDELKVDL 62 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 + + + E I+ + V + AE +YDY Sbjct: 63 SEA--LPEKGIQFQEGTVEKIDAKSSMV----------------YYTKPDGSMAEEEYDY 104 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAA----NLEKANLLPKGDPERRR 227 +I +GA T + G YG+ + E + ++R + N+ + + Sbjct: 105 VIVGIGAHLATELVKGWDKYGYSVCEPEFATKLREKLESFQGGNIAIGSGPFYQGHNPKP 164 Query: 228 LLSIVVVGGGPTGVEA-AGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 + V + E E+ +H +K + ++V + + L+ Sbjct: 165 KVPENFVPNADSACEGPVFEMSLMLHGYFKK--KGMLDKVHVTVFSPGE-YLSDLSPNSR 221 Query: 287 SYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPV 346 S IK+ + ++ E +++ TIP I P Sbjct: 222 KAVASIYNQLGIKLVHNFKIKEIREHEIV--------DEKGNTIPADITILLPPYTGNPA 273 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKN 406 + + P+ + + + +N++A+GD +P +A A++ Sbjct: 274 LKNS---TPDLVDDGGFIPTDLNMVSIKYDNVYAVGDANSMTVPKLGYLAVMTGRIAAQH 330 Query: 407 FDKMAQIPN 415 +P Sbjct: 331 LANRLGVPT 339 >5VDN-A nrPDB Length = 463 Score = 85.7 bits (210), Expect = 5e-17, Method: Composition-based stats. Identities = 57/303 (18%), Positives = 94/303 (31%), Gaps = 76/303 (25%) Query: 160 HQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLP 219 + I D+++ A G P+ IPG +YG E+ Sbjct: 136 VEVNGETITADHILIATGGRPSHPDIPGA-EYGIDSDGFFELDEM--------------- 179 Query: 220 KGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN 279 + VVG G VE AG L L E + + + P L Sbjct: 180 --------PKRVAVVGAGYIAVEIAGVLN------------GLGTETHLFVRKHAP--LR 217 Query: 280 MFEKKLSSYAQSHLENTSIKVHLRT---AVAKVEEKQLLAKTKHEDGKITEETIPYGTLI 336 F+ + + K+H + AV K + L + ++ + LI Sbjct: 218 TFDPLIVETLLEVMNTEGPKLHTESVPKAVIKNADGSLTLQLEN------GTEVTVDHLI 271 Query: 337 WATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVA 396 WA G P +L + ++ +G D Q I+A+GDN G+ VA Sbjct: 272 WAIGR--EPATDNLNLSVTGVKTNDKGYIEVDKFQNTNVKGIYAVGDN--TGVVELTPVA 327 Query: 397 HQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAI 456 L+ + LF + Y+++ + + S I Sbjct: 328 VAAGRRLS-----------------------ERLFNNKPDEHLDYSNIPTVVF--SHPPI 362 Query: 457 ATI 459 TI Sbjct: 363 GTI 365 >3CGD-A nrPDB Length = 480 Score = 84.9 bits (208), Expect = 7e-17, Method: Composition-based stats. Identities = 61/337 (18%), Positives = 114/337 (33%), Gaps = 60/337 (17%) Query: 55 NVLILGSGWGAISFLKHI--DTKKYNVSIISPRSYFLFTPL-LPSAPVGTV--DEKSIIE 109 N +I+G +S I + + NV + + + LP G + EK I Sbjct: 38 NYVIIGGDAAGMSAAMQIVRNDENANVVTLEKGEIYSYAQCGLPYVISGAIASTEKLIAR 97 Query: 110 PIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKY 169 + F K G E T ++ ++ V + E Y Sbjct: 98 NVKTF-RDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVF---------------EFSY 141 Query: 170 DYLISAVGAEPNTFGIPGVTDYG-HFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRL 228 D L+ A G P G G H LK IP++ I +T N + Sbjct: 142 DRLLIATGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVED------------- 188 Query: 229 LSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSY 288 + ++GGG G+E A + ++ ++E + +++ ++ Y Sbjct: 189 --VTIIGGGAIGLEMAETFVEL--------------GKKVRMIERNDHIGTIYDGDMAEY 232 Query: 289 AQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVIT 348 + I++ V K + E + + T ++ + G K T Sbjct: 233 IYKEADKHHIEILTNENV-----KAFKGNERVEAVETDKGTYKADLVLVSVGVKPN---T 284 Query: 349 DLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 D + + + K + VN ++Q +++A GD A Sbjct: 285 DFLEGTNIRTNHKGAIEVNAYMQT-NVQDVYAAGDCA 320 >5U1O-A nrPDB Length = 458 Score = 84.1 bits (206), Expect = 1e-16, Method: Composition-based stats. Identities = 50/289 (17%), Positives = 87/289 (30%), Gaps = 50/289 (17%) Query: 122 VTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPN 181 V +A I+ + V + V + + + D+++ AVG P Sbjct: 92 VESRQAYIGRIHQSYDRVLGNNKVNVIKGFAKFVDEKTVEVNGEHYTADHILIAVGGRPT 151 Query: 182 TFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGV 241 IPG +YG + E + + VVG G V Sbjct: 152 IPNIPGA-EYGIDSNGFFDLAE-----------------------QPKRVAVVGAGYIAV 187 Query: 242 EAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVH 301 E AG L + HL L F+ + +E +H Sbjct: 188 EIAGVLHAL--------------GTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLH 233 Query: 302 LRT---AVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQN 358 + V K + L ++ E+ LIWA G +L Sbjct: 234 THSVPKEVVKEADGSLTLHLEN------GESQNVDQLIWAIGRHPATDAINLAST-GVAT 286 Query: 359 SSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 407 + K + V+++ + I+ +GD G+ VA + L++ Sbjct: 287 NEKGYIKVDEYQET-NVKGIYCVGDIMEGGI-ELTPVAVKAGRQLSERL 333 >6DU7-A nrPDB Length = 448 Score = 83.7 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 57/347 (16%), Positives = 110/347 (31%), Gaps = 75/347 (21%) Query: 113 NFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYL 172 +FA ++ +Y + +S + ++ + + + I+ ++ Sbjct: 79 DFATLRRNRESYIDRARSSYDGSFK----RNGVDLIEGHAEFVDSHTVSVNGELIRAKHI 134 Query: 173 ISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIV 232 + A GA P+ IPG + G ++ E+ S+ Sbjct: 135 VIATGAHPSIPNIPGA-ELGGSSDDVFAWEEL-----------------------PESVA 170 Query: 233 VVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSH 292 ++G G VE AG L + V+ L L F+ + Sbjct: 171 ILGAGYIAVELAGVLHTF--------------GVKTDLFVRRDRPLRGFDSYIVEGLVKE 216 Query: 293 LENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFK 352 +E T++ +H K+E+ EDG +IWATG + L + Sbjct: 217 MERTNLPLHTHKVPVKLEKTTDGITIHFEDGTSH----TASQVIWATGRRPNVKGLQL-E 271 Query: 353 KIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQ 412 K + + + V+++ I+A+GD G VA + L+ Sbjct: 272 KAGVTLNERGFIQVDEYQNTV-VEGIYALGDV--TGEKELTPVAIKAGRTLS-------- 320 Query: 413 IPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATI 459 + LF Y+ + + + S AI T+ Sbjct: 321 ---------------ERLFNGKTTAKMDYSTIPTVVF--SHPAIGTV 350 >2CDU-A nrPDB Length = 452 Score = 83.4 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 57/292 (19%), Positives = 101/292 (34%), Gaps = 65/292 (22%) Query: 128 EATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPG 187 + T+++P+ T+ +K L E YD LI G++P IPG Sbjct: 80 QVTNVDPETKTIKVKDLITN---------------EEKTEAYDKLIMTTGSKPTVPPIPG 124 Query: 188 VTDYGHFL-KEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGE 246 + +L K ++ ++ E + +I ++G G G E A Sbjct: 125 IDSSRVYLCKNYNDAKKL-----------------FEEAPKAKTITIIGSGYIGAELAEA 167 Query: 247 LQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQSHLENTSIKVHLRTA 305 + + ++L++ VL F+K+ + E + + L + Sbjct: 168 YSNQNY--------------NVNLIDGHERVLYKYFDKEFTDILAKDYEAHGVNLVLGSK 213 Query: 306 VAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLA 365 VA EE TK DGK I I G + T+L K + Sbjct: 214 VAAFEEVDDEIITKTLDGK----EIKSDIAILCIGFRPN---TELLKG-KVAMLDNGAII 265 Query: 366 VNDFLQVKGSNNIFAIGDNAFAG-LP-------PTAQVAHQEAEYLAKNFDK 409 ++++ + IFA GD+A P P A A ++ + N + Sbjct: 266 TDEYMHSSNRD-IFAAGDSAAVHYNPTNSNAYIPLATNAVRQGRLVGLNLTE 316 >1GEU-A nrPDB Length = 450 Score = 83.4 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 57/284 (20%), Positives = 90/284 (31%), Gaps = 51/284 (17%) Query: 127 AEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIP 186 A I+ V K+ V + + + I D+++ A G P+ IP Sbjct: 90 AYIDRIHTSYENVLGKNNVDVIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIP 149 Query: 187 GVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGE 246 GV +YG PER + VVG G GVE G Sbjct: 150 GV-EYGIDSD------------------GFFALPALPER-----VAVVGAGYIGVELGGV 185 Query: 247 LQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLR--- 303 + + HL E L F+ +S + ++H Sbjct: 186 IN--------------GLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEGPQLHTNAIP 231 Query: 304 TAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRG 363 AV K + L + + + LIWA G P ++ + ++++G Sbjct: 232 KAVVKNTDGSLTLELEDGRSE------TVDCLIWAIGR--EPANDNINLEAAGVKTNEKG 283 Query: 364 LAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 407 V D Q I+A+GDN G VA L++ Sbjct: 284 YIVVDKYQNTNIEGIYAVGDN--TGAVELTPVAVAAGRRLSERL 325 >3FG2-P nrPDB Length = 404 Score = 82.6 bits (202), Expect = 4e-16, Method: Composition-based stats. Identities = 65/372 (17%), Positives = 129/372 (34%), Gaps = 78/372 (20%) Query: 56 VLILGSGWGAISFLKHIDTKKY--NVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVN 113 VLI G+G + KY +++I+ + + P + ++ Sbjct: 4 VLIAGAGHAGFQVAVSLRQAKYPGRIALINDEKHLPYQR--PPLSKAYLKSGGDPNSLMF 61 Query: 114 FALK--KKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 K + + SI+ + + + S +A I+Y + Sbjct: 62 RPEKFFQDQAIELISDRMVSIDREGRKLLLASGTA--------------------IEYGH 101 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 L+ A GA +P +P+ L +R L+++ +L + P+++ + Sbjct: 102 LVLATGARNRMLDVPNA--------SLPDVLYLR-----TLDESEVLRQRMPDKK---HV 145 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQ 290 VV+G G G+E A + A+ +++ +VE P V+ + ++SSY Sbjct: 146 VVIGAGFIGLEFAATAR--------------AKGLEVDVVELAPRVMARVVTPEISSYFH 191 Query: 291 SHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKI--TEETIPYGTLIWATGNKARPVIT 348 I++H V ++ A+ G + T+P ++ G I Sbjct: 192 DRHSGAGIRMHY-----GVRATEIAAEGDRVTGVVLSDGNTLPCDLVVVGVGVIPNVEIA 246 Query: 349 DLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAF--------AGLPPTAQVAHQEA 400 + G+ V+ L + +I AIGD A + Q A +A Sbjct: 247 -----AAAGLPTAAGIIVDQQL-LTSDPHISAIGDCALFESVRFGETMRVESVQNATDQA 300 Query: 401 EYLAKNFDKMAQ 412 +A A+ Sbjct: 301 RCVAARLTGDAK 312 >2BC1-A nrPDB Length = 490 Score = 82.2 bits (201), Expect = 5e-16, Method: Composition-based stats. Identities = 62/343 (18%), Positives = 118/343 (34%), Gaps = 63/343 (18%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 ++++G+ + +K + T + + I L S + E+ I P F Sbjct: 37 KIVVVGANHAGTACIKTMLTNYGDANEIVVFDQNSNISFLGSGMALWIGEQ-IAGPEGLF 95 Query: 115 ALKKK-----GNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKY 169 K+ G Y E+ SI+ D TVT L + Y Sbjct: 96 YSDKEELESLGAKVYMESPVQSIDYDAKTVT-----------------ALVDGKNHVETY 138 Query: 170 DYLISAVGAEPNTFGIPGVT------DYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDP 223 D LI A G++P I G ++ L+ + +++ + A + K Sbjct: 139 DKLIFATGSQPILPPIKGAEIKEGSLEFEATLENL-QFVKLYQNSADVIAK--------L 189 Query: 224 ERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN-MFE 282 E + + + VVG G GVE A Q + ++ L++ + L ++ Sbjct: 190 ENKDIKRVAVVGAGYIGVELAEAFQ--------------RKGKEVVLIDVVDTCLAGYYD 235 Query: 283 KKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNK 342 + L+ ++E I++ V +V K E + +I A G + Sbjct: 236 RDLTDLMAKNMEEHGIQLAFGETVKEVAGNG-----KVEKIITDKNEYDVDMVILAVGFR 290 Query: 343 ARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 + + + + G + + Q ++AIGD A Sbjct: 291 PNTTL-----GNGKIDLFRNGAFLVNKRQETSIPGVYAIGDCA 328 >3T14-A nrPDB Length = 437 Score = 81.0 bits (198), Expect = 1e-15, Method: Composition-based stats. Identities = 62/329 (18%), Positives = 115/329 (34%), Gaps = 47/329 (14%) Query: 56 VLILGSGWGAISF---LKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIV 112 V+ILG+G G + +K + V++IS YF F P P VG + I PI Sbjct: 7 VVILGAGTGGMPAAYEMKEALGSGHEVTLISANDYFQFVPSNPWVGVGWKERDDIAFPIR 66 Query: 113 NFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYL 172 ++ +K + + A I+ + +T+ A+ + YDYL Sbjct: 67 HYVERK--GIHFIAQSAEQIDAEAQNITL--------------------ADGNTVHYDYL 104 Query: 173 ISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIV 232 + A G + +PG + ++ I R FA E LL + P + Sbjct: 105 MIATGPKLAFENVPGSDPHEGPVQSIATVDHAERAFA---EYQALLREPGP--------I 153 Query: 233 VVGGGPTGVEAAGELQDYVHQDLRKFLPALAEE--VQIHLVEALPIVLNMFEKKLSS--- 287 V+G G G +Y + + + P + ++ + + Sbjct: 154 VIGA-MAGASCFGPAYEYAMIVASDLKKRGMRDKIPSFTFITSEPYIGHLGIQGVGDSKG 212 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGK-ITEETIPYGTLIWATGNKARPV 346 L+ I+ + V KVE+ ++ E G+ I E +P + K P Sbjct: 213 ILTKGLKEEGIEAYTNCKVTKVEDNKMYVTQVDEKGETIKEMVLPVKFGMMIPAFKGVPA 272 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGS 375 + + + + V++ + K Sbjct: 273 VA----GVEGLCNPGGFVLVDEHQRSKKY 297 >2HQM-A nrPDB Length = 479 Score = 80.7 bits (197), Expect = 1e-15, Method: Composition-based stats. Identities = 48/280 (17%), Positives = 91/280 (32%), Gaps = 47/280 (16%) Query: 151 YQPENHLGLHQAEPAEIKY--DYLISAVGAEPNTF-GIPGVTDYGHFLKEIPNSLEIRRT 207 + + ++ + + + Y ++++ A G + IPG Sbjct: 129 FNKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPG-------------------- 168 Query: 208 FAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQ 267 E + +VVVG G G+E AG + Sbjct: 169 ----FELGTDSDGFFRLEEQPKKVVVVGAGYIGIELAGVFH--------------GLGSE 210 Query: 268 IHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITE 327 HLV VL F++ + + H I VH + + KVE+ K K ++ Sbjct: 211 THLVIRGETVLRKFDECIQNTITDHYVKEGINVHKLSKIVKVEKNVETDKLKIHMND-SK 269 Query: 328 ETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFA 387 LIW G K+ + + + + +S + +++ Q NI+++GD Sbjct: 270 SIDDVDELIWTIGRKSHLGMGS--ENVGIKLNSHDQIIADEY-QNTNVPNIYSLGDV--V 324 Query: 388 GLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKI 427 G VA L+ + N + + + I Sbjct: 325 GKVELTPVAIAAGRKLSNRLFGPEKFRNDKLDYENVPSVI 364 >1NHQ-A nrPDB Length = 447 Score = 80.7 bits (197), Expect = 1e-15, Method: Composition-based stats. Identities = 63/367 (17%), Positives = 129/367 (35%), Gaps = 65/367 (17%) Query: 55 NVLILGSGWGAISFLKHIDT--KKYNVSIISPRSYFLF-TPLLPSAPVGTVDEKSIIEPI 111 V++LGS G ++ + + + F + + G V + + + + Sbjct: 2 KVIVLGSSHGGYEAVEELLNLHPDAEIQWYEKGDFISFLSSGMQLYLEGKVKDVNSVRYM 61 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 ++ +G + E T+I P + VT+K L + + + YD Sbjct: 62 TGEKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVE---------------NYDK 106 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 LI + GA P IPG K++ N +R A K + DPE + Sbjct: 107 LIISPGAVPFELDIPG--------KDLDNIYLMRGRQWAIKLKQKTV---DPEVNN---V 152 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN-MFEKKLSSYAQ 290 VV+G G G+EAA ++ +++ L L +K+ + Sbjct: 153 VVIGSGYIGIEAAEAFA--------------KAGKKVTVIDILDRPLGVYLDKEFTDVLT 198 Query: 291 SHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDL 350 +E +I + V + E + K + + ++ A G + Sbjct: 199 EEMEANNITIATGETVERYEGDGRVQKVVTD-----KNAYDADLVVVAVGVRPNTA---- 249 Query: 351 FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAG-LPPTAQV-------AHQEAEY 402 + K + + +++++ ++FA+GD P +V A ++ + Sbjct: 250 WLKGTLELHPNGLIKTDEYMRTS-EPDVFAVGDATLIKYNPADTEVNIALATNARKQGRF 308 Query: 403 LAKNFDK 409 KN ++ Sbjct: 309 AVKNLEE 315 >1LVL-A nrPDB Length = 458 Score = 79.9 bits (195), Expect = 3e-15, Method: Composition-based stats. Identities = 43/178 (24%), Positives = 75/178 (42%), Gaps = 23/178 (12%) Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 +VVVGGG G+E + Q+ +VEA +L ++ +L++ Sbjct: 171 PQHLVVVGGGYIGLELGIAYRKL--------------GAQVSVVEARERILPTYDSELTA 216 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 L+ I +HL +V E LLA DGK + + ++ A G + R Sbjct: 217 PVAESLKKLGIALHLGHSVEGYENGCLLA----NDGKGGQLRLEADRVLVAVGRRPRT-- 270 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 + + + +A+++ Q +N++AIGD AG P A A + E +A+ Sbjct: 271 KGFNLECLDLKMNGAAIAIDERCQTS-MHNVWAIGDV--AGEPMLAHRAMAQGEMVAE 325 >1EBD-A nrPDB Length = 455 Score = 79.5 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 63/357 (17%), Positives = 129/357 (36%), Gaps = 39/357 (10%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 L++G+G G V+I+ + VG + K++I + Sbjct: 5 ETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGV-----CLNVGCIPSKALISASHRY 59 Query: 115 ALKKKGNVTYYEAEATSIN----PDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 K +AE +I+ + +K L+ + N + + + E + + Sbjct: 60 EQAKHSEEMGIKAENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFVDAN 119 Query: 171 YLISAVGAEPNTFGI-PGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 + G T+ + G E+PN + + NL Sbjct: 120 TVRVVNGDSAQTYTFKNAIIATGSRPIELPN-FKFSNRILDSTGALNLGEV-------PK 171 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 S+VV+GGG G+E ++ ++ ++E +L+ FEK++++ Sbjct: 172 SLVVIGGGYIGIELGTAYANF--------------GTKVTILEGAGEILSGFEKQMAAII 217 Query: 290 QSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITD 349 + L+ ++V EE++ +E T+ TI ++ G + + Sbjct: 218 KKRLKKKGVEVVTNALAKGAEEREDGVTVTYEANGETK-TIDADYVLVTVGRRPNT--DE 274 Query: 350 L-FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 L ++I + +++ + V+ + NIFAIGD P A A E + A+ Sbjct: 275 LGLEQIGIKMTNRGLIEVDQQCRTS-VPNIFAIGDIVPG--PALAHKASYEGKVAAE 328 >1YQZ-A nrPDB Length = 438 Score = 79.1 bits (193), Expect = 4e-15, Method: Composition-based stats. Identities = 55/284 (19%), Positives = 99/284 (34%), Gaps = 54/284 (19%) Query: 135 DRNTVTIKS---LSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDY 191 DR +T+K+ + A++ Q + L E E YD LI + GA N+ G +D Sbjct: 69 DRKQITVKTYHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSLGFE--SDI 126 Query: 192 GHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYV 251 L+ + ++ I + AN ++ ++VVG G +E L + Sbjct: 127 TFTLRNLEDTDAIDQFIKAN---------------QVDKVLVVGAGYVSLEVLENLYE-- 169 Query: 252 HQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEE 311 + L+ + + + ++ L+ I L + + Sbjct: 170 ------------RGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYRLNEEINAIN- 216 Query: 312 KQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQ 371 +E + + Y +I G + + + K + VND + Sbjct: 217 -------GNEITFKSGKVEHYDMIIEGVGTHPN---SKFIESSNIKLDRKGFIPVNDKFE 266 Query: 372 VKGSNNIFAIGDNA-----FAGLP---PTAQVAHQEAEYLAKNF 407 NI+AIGD A LP P A AH+ A +A+ Sbjct: 267 T-NVPNIYAIGDIATSHYRHVDLPASVPLAWGAHRAASIVAEQI 309 >2WOV-A nrPDB Length = 495 Score = 78.7 bits (192), Expect = 5e-15, Method: Composition-based stats. Identities = 46/242 (19%), Positives = 79/242 (32%), Gaps = 42/242 (17%) Query: 162 AEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKG 221 A ++ D+++ A G+ P IPG+ E + Sbjct: 149 AVKERLQADHILLATGSWPQMPAIPGI------------------------EHCISSNEA 184 Query: 222 DPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMF 281 ++ VGGG VE AG Y ++ L ++L F Sbjct: 185 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPP-----------GGKVTLCYRNNLILRGF 233 Query: 282 EKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGN 341 ++ + L I++ AKV L + +T+ ++ A G Sbjct: 234 DETIREEVTKQLTANGIEIMTNENPAKV---SLNTDGSKHVTFESGKTLDVDVVMMAIGR 290 Query: 342 KARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 R L + + + K G+ V++F + NI+AIGD + VA E Sbjct: 291 IPRTNDLQL-GNVGVKLTPKGGVQVDEFSRT-NVPNIYAIGDITDRLM--LTPVAINEGA 346 Query: 402 YL 403 L Sbjct: 347 AL 348 >6CMZ-A nrPDB Length = 466 Score = 77.2 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 40/178 (22%), Positives = 73/178 (41%), Gaps = 22/178 (12%) Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 +VVVG G G+E L L V + +VEA VL ++ +L Sbjct: 178 PKRLVVVGAGYIGLE------------LGIVYRKLG--VDVSVVEAAERVLPAYDAELVR 223 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 L +++ L V +++ + + + E+T+P ++ A G + R + Sbjct: 224 PVADSLARLGVRLWLGHKVLGLDKHGAV---RVQAADGAEQTLPADRVLVAVGRRPR--V 278 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 + + + R L ++D + N++AIGD AG P A A + E +A+ Sbjct: 279 DGFGLETLMLDRNGRALRIDDTCRTS-MRNVWAIGDV--AGEPMLAHRAMAQGEMVAE 333 >2V3B-A nrPDB Length = 384 Score = 75.3 bits (183), Expect = 6e-14, Method: Composition-based stats. Identities = 69/372 (18%), Positives = 127/372 (34%), Gaps = 67/372 (18%) Query: 51 SDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEP 110 S++ ++I+G+G + + R TPLL + Sbjct: 2 SERAPLVIIGTGLAGYNLAREW------------RKLDGETPLLMITADDGRSYSKPMLS 49 Query: 111 IVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 K + E A + + +T ++ + +Q E++Y Sbjct: 50 TGFSKNKDADGLAMAEPGAMAEQLNARILTHTRVTGIDPGHQR------IWIGEEEVRYR 103 Query: 171 YLISAVGAEPNTFGIPG-VTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 L+ A GAEP + G D + + ++ + R+ A Sbjct: 104 DLVLAWGAEPIRVPVEGDAQDALYPINDLEDYARFRQAAAGKRR---------------- 147 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSY- 288 ++++G G G E A +L Q+ +V V+ ++ Sbjct: 148 -VLLLGAGLIGCEFANDLSSG--------------GYQLDVVAPCEQVMPGLLHPAAAKA 192 Query: 289 AQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVIT 348 Q+ LE ++ HL +A +++ + DG E IP ++ A G + R + Sbjct: 193 VQAGLEGLGVRFHLGPVLASLKKAGEGLEAHLSDG----EVIPCDLVVSAVGLRPRTELA 248 Query: 349 DLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFA-GLP-----PTAQVAHQEAEY 402 + RG+ V+ L+ NI+A+GD A GL P A A+ Sbjct: 249 -----FAAGLAVNRGIVVDRSLRTS-HANIYALGDCAEVDGLNLLYVMPLMACARALAQT 302 Query: 403 LAKNFDKMAQIP 414 LA N ++A P Sbjct: 303 LAGNPSQVAYGP 314 >4NEW-A nrPDB Length = 492 Score = 74.9 bits (182), Expect = 7e-14, Method: Composition-based stats. Identities = 49/242 (20%), Positives = 84/242 (34%), Gaps = 43/242 (17%) Query: 162 AEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKG 221 A ++ ++++ A G+ P+ IPG+ E + Sbjct: 147 AVKERLETEHILLASGSWPHMPNIPGI------------------------EHCISSNEA 182 Query: 222 DPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMF 281 ++ VGGG VE AG Y +D Q+ L ++L F Sbjct: 183 FYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDG-----------QVTLCYRGEMILRGF 231 Query: 282 EKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGN 341 + L L I++ + AKVE L A + + + + ++ A G Sbjct: 232 DHTLREELTKQLTANGIQILTKENPAKVE---LNADGSKSVTFESGKKMDFDLVMMAIGR 288 Query: 342 KARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 R DL + G+ V+++ + +NI+AIGD + VA EA Sbjct: 289 SPRT--KDLQLQNAGVMIKNGGVQVDEYSRT-NVSNIYAIGDVTNRVM--LTPVAINEAA 343 Query: 402 YL 403 L Sbjct: 344 AL 345 >6N7F-A nrPDB Length = 453 Score = 71.4 bits (173), Expect = 8e-13, Method: Composition-based stats. Identities = 59/320 (18%), Positives = 93/320 (29%), Gaps = 82/320 (25%) Query: 147 VSQLYQPENHLGLHQAEPAEIKYD--YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEI 204 V ++Y H E A Y +++ A G P I G YG E+ Sbjct: 111 VDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGA-QYGISSDGFFALDEV 169 Query: 205 RRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAE 264 VVG G VE AG L AL Sbjct: 170 -----------------------PKRTAVVGAGYIAVELAGVLH------------ALGS 194 Query: 265 EVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGK 324 + + + P L F+K + + ++H VAKV K+ D Sbjct: 195 KTDLFIRHDRP--LRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKV--------VKNTDES 244 Query: 325 IT-----EETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIF 379 +T + + LIWA G K L K + K + + + + I+ Sbjct: 245 LTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKT-GVTLNDKGYIETDAY-ENTSVKGIY 302 Query: 380 AIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPF 439 A+GD G VA L+ + LF + Sbjct: 303 AVGDV--NGKLALTPVAVAAGRRLS-----------------------ERLFNGKTDEKL 337 Query: 440 KYNDLGALAYLGSERAIATI 459 Y ++ + + S I ++ Sbjct: 338 DYQNVATVIF--SHPVIGSV 355 >1DXL-A nrPDB Length = 470 Score = 69.5 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 60/294 (20%), Positives = 101/294 (34%), Gaps = 63/294 (21%) Query: 116 LKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISA 175 L KK VTY + ++P +V + E +K ++I A Sbjct: 105 LFKKNKVTYVKGYGKFVSPSEISVDT------------------IEGENTVVKGKHIIIA 146 Query: 176 VGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVG 235 G + +PGVT I + T A L + +VV+G Sbjct: 147 TG--SDVKSLPGVT--------IDEKKIVSSTGALALSEI------------PKKLVVIG 184 Query: 236 GGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLEN 295 G G+E G + + ++ +VE ++ + ++ Q LE Sbjct: 185 AGYIGLEM-GSVWGRI-------------GSEVTVVEFASEIVPTMDAEIRKQFQRSLEK 230 Query: 296 TSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEET-IPYGTLIWATGNKARPVITDLFKKI 354 +K L+T V V+ K E E+T I ++ + G +L K I Sbjct: 231 QGMKFKLKTKVVGVDTSGDGVKLTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDK-I 289 Query: 355 PEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEA----EYLA 404 + + VN+ + ++AIGD P A A ++ EYLA Sbjct: 290 GVETDKLGRILVNERFST-NVSGVYAIGDVIPG--PMLAHKAEEDGVACVEYLA 340 >1FEC-A nrPDB Length = 490 Score = 69.5 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 43/231 (18%), Positives = 71/231 (30%), Gaps = 42/231 (18%) Query: 170 DYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 +Y++ A G+ P GI G ++ + Sbjct: 153 EYILLATGSWPQHLGIEG--------DDL----------------CITSNEAFYLDEAPK 188 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 + VGGG +E AG Y A Q+ L ++L F+ +L Sbjct: 189 RALCVGGGYISIEFAGIFNAYK-----------ARGGQVDLAYRGDMILRGFDSELRKQL 237 Query: 290 QSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITD 349 L I V AKV + + Y ++ A G R Sbjct: 238 TEQLRANGINVRTHENPAKVTKNA---DGTRHVVFESGAEADYDVVMLAIGRVPRSQTLQ 294 Query: 350 LFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEA 400 L +K + + + V+ + + +NI+AIGD + VA E Sbjct: 295 L-EKAGVEVAKNGAIKVDAYSKT-NVDNIYAIGDVTDRVM--LTPVAINEG 341 >2YVG-A nrPDB Length = 408 Score = 69.1 bits (167), Expect = 5e-12, Method: Composition-based stats. Identities = 65/407 (15%), Positives = 137/407 (33%), Gaps = 91/407 (22%) Query: 49 QHSDKPNVLILGSGWGAISFLKHIDTKKYN--VSIISP---RSYFLFTPLLPSAPVGTVD 103 Q + K V++LG+G ++SF+ + Y ++++ R Y Sbjct: 3 QEALKAPVVVLGAGLASVSFVAELRQAGYQGLITVVGDEAERPY---------------- 46 Query: 104 EKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAE 163 + K + + +AE ++ R L +Q + P+ H + ++ Sbjct: 47 ---------DRPPLSKDFMAHGDAEKIRLDCKRAPEVEWLLGVTAQSFDPQAHT-VALSD 96 Query: 164 PAEIKYDYLISAVGAEPNT-FGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGD 222 + Y L+ A GA P + G T H L+ + ++ I+ Sbjct: 97 GRTLPYGTLVLATGAAPRALPTLQGATMPVHTLRTLEDARRIQAGL-------------- 142 Query: 223 PERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMF 281 R +++VGGG G+E A + V + LVE P ++ Sbjct: 143 ---RPQSRLLIVGGGVIGLELAATARTA--------------GVHVSLVETQPRLMSRAA 185 Query: 282 EKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGN 341 L+ + + + + +V + +L I ++ G Sbjct: 186 PATLADFVARYHAAQGVDLRFERSVTGSVDGVVLLD--------DGTRIAADMVVVGIGV 237 Query: 342 KARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 A + + G+ V+ + + +++A+GD P Sbjct: 238 LANDALAR-----AAGLACDDGIFVDAYGRTT-CPDVYALGDVTRQRNP----------- 280 Query: 402 YLAKNFDKMAQIPNFQ-KNLSSRKDKIDLLFEENNFKPFKYNDLGAL 447 L+ F+++ N Q + ++ + +D P+ ++D GAL Sbjct: 281 -LSGRFERIETWSNAQNQGIAVARHLVDPTAPGYAELPWYWSDQGAL 326 >5V36-A nrPDB Length = 453 Score = 69.1 bits (167), Expect = 5e-12, Method: Composition-based stats. Identities = 49/266 (18%), Positives = 77/266 (28%), Gaps = 53/266 (19%) Query: 147 VSQLYQPENHLGLHQAEPAEIKYD--YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEI 204 V ++Y + H E A Y +++ A G IPG ++YG I Sbjct: 111 VERVYGYATFVDAHTVEVAGEHYTAPHILIATGGHALLPDIPG-SEYGITSDGFFELDAI 169 Query: 205 RRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAE 264 VVG G VE +G L Sbjct: 170 -----------------------PKRTAVVGAGYIAVEISGILHAL-------------- 192 Query: 265 EVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHL---RTAVAKVEEKQLLAKTKHE 321 + HL L F+K++ ++ +H V K + L ++ Sbjct: 193 GSETHLFVRRDRPLRKFDKEIVGTLVDEMKKDGPHLHTFSVPKEVIKNTDNSLTLILEN- 251 Query: 322 DGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAI 381 E TLIWA G A ++ RG D + ++A+ Sbjct: 252 -----GEEYTVDTLIWAIGRAANT--KGFNLEVTGVTLDSRGFIATDAFENTNVEGLYAL 304 Query: 382 GDNAFAGLPPTAQVAHQEAEYLAKNF 407 GD G VA + L++ Sbjct: 305 GDV--NGKLELTPVAVKAGRQLSERL 328 >4YWO-A nrPDB Length = 462 Score = 68.7 bits (166), Expect = 6e-12, Method: Composition-based stats. Identities = 47/242 (19%), Positives = 92/242 (38%), Gaps = 51/242 (21%) Query: 167 IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 226 I+ + + A G+ P IPG+ G F N E R Sbjct: 135 IEAEKFVIATGSSPLIPRIPGLDKVG---------------FWTNRE-------ALSPDR 172 Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 R+ S+ V+GG +E A +V++ +++ P+++ +E + S Sbjct: 173 RIDSLAVIGGRALALEFAQMYSRM--------------KVEVAILQRSPVLIPDWEPEAS 218 Query: 287 SYAQSHLENTSIKVHLRTAVAKVEE--KQLLAKTKHEDGKITEETIPYGTLIWATGNKAR 344 A+ +EN + V V +V + +++ K E + ++ ATG K Sbjct: 219 VEARRIMENDGVAVVTGVNVKEVRKGAGKIVITDKGE--------VEADEILLATGRK-- 268 Query: 345 PVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLA 404 P + + + + + G+ V+D L+ +I+A GD G +A ++ Sbjct: 269 PNVDLGLENAGVRLNERGGIKVDDELRTDN-PHIYAAGDVL--GGKMLEALAGRQGSIAT 325 Query: 405 KN 406 +N Sbjct: 326 EN 327 >6B4O-A nrPDB Length = 452 Score = 68.3 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 50/255 (19%), Positives = 79/255 (30%), Gaps = 47/255 (18%) Query: 155 NHLGLHQAEPAEIKYD--YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANL 212 G E +Y +++ A G P GIPG +Y +L+ FA Sbjct: 118 TFTGEQTIEVNGTEYTAPHILIATGGRPKKLGIPG-EEY---------ALDSNGFFAL-- 165 Query: 213 EKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVE 272 +V VG G E AG L + F Sbjct: 166 ------------EEMPKRVVFVGAGYIAAELAGTLHGLGAETHWAFRH------------ 201 Query: 273 ALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPY 332 L F+ LS + +++H AK+E+ + ++ E+I Sbjct: 202 --ERPLRSFDDMLSEKVVERYQEMGMQIHPNATPAKIEKTA---QNEYVITFENGESITT 256 Query: 333 GTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPT 392 +I+ TG + L + K + V D Q N I+A+GD G Sbjct: 257 DAVIFGTGRQPNTDQLGL-ENTKVALDEKGYVKV-DKFQNTTQNGIYAVGDVI--GKIDL 312 Query: 393 AQVAHQEAEYLAKNF 407 VA L++ Sbjct: 313 TPVAIAAGRRLSERL 327 >3Q6J-A nrPDB Length = 523 Score = 68.3 bits (165), Expect = 7e-12, Method: Composition-based stats. Identities = 59/319 (18%), Positives = 108/319 (33%), Gaps = 60/319 (18%) Query: 93 LLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSI----NPDRNTVTIKSLSAVS 148 P V K +++ G + + E ++ N + ++ A Sbjct: 111 WFPDMTEKVVGIKEVVDLFRAGRNGPHGIMNFQSKEQLNLEYILNCPAKVIDNHTVEAAG 170 Query: 149 QLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTF 208 ++++ +N LI AVGA P T +PGV G F Sbjct: 171 KVFKAKN----------------LILAVGAGPGTLDVPGVNAKGVF------------DH 202 Query: 209 AANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQI 268 A +E+ + P ++VVVGG T VE F A + Sbjct: 203 ATLVEELDYEPGS--------TVVVVGGSKTAVEY------------GCFFNATGRRTVM 242 Query: 269 HLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQ-LLAKTKHEDGKITE 327 + ++ + + +Y ++ +++ + V ++EE + E Sbjct: 243 LVRTEPLKLIK--DNETRAYVLDRMKEQGMEIISGSNVTRIEEDANGRVQAVVAMTPNGE 300 Query: 328 ETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFA 387 I + G + R +L K + K + VN++LQ N++A+GD Sbjct: 301 MRIETDFVFLGLGEQPRS--AELAKILGLDLGPKGEVLVNEYLQTS-VPNVYAVGDLI-- 355 Query: 388 GLPPTAQVAHQEAEYLAKN 406 G P A + Y A+N Sbjct: 356 GGPMEMFKARKSGCYAARN 374 >2AAQ-A nrPDB Length = 479 Score = 67.6 bits (163), Expect = 1e-11, Method: Composition-based stats. Identities = 49/268 (18%), Positives = 81/268 (30%), Gaps = 50/268 (18%) Query: 160 HQAEPAEIKYDYLISAVGAEPNTF---GIPGVTDYGHFLKEIPNSLEIRRTFAANLEKAN 216 + + +++ A G P+T IPG + G E+ Sbjct: 141 IEVSGKKYTAPHILIATGGMPSTPHESQIPGAS-LGITSDGFFQLEEL------------ 187 Query: 217 LLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPI 276 V+VG G VE AG L AL + + + Sbjct: 188 -----------PGRSVIVGAGYIAVEMAG------------ILSALGSKTSLMIRH--DK 222 Query: 277 VLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPY---- 332 VL F+ +S+ LEN ++V + V +V++ + + Sbjct: 223 VLRSFDSMISTNCTEELENAGVEVLKFSQVKEVKKTLSGLEVSMVTAVPGRLPVMTMIPD 282 Query: 333 -GTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPP 391 L+WA G K+ Q K + V++ Q I+A+GD G Sbjct: 283 VDCLLWAIGRVPNTK-DLSLNKLGIQTDDKGHIIVDE-FQNTNVKGIYAVGDV--CGKAL 338 Query: 392 TAQVAHQEAEYLAKNFDKMAQIPNFQKN 419 VA LA + + N Sbjct: 339 LTPVAIAAGRKLAHRLFEYKEDSKLDYN 366 >3KLJ-A nrPDB Length = 385 Score = 67.2 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 73/359 (20%), Positives = 123/359 (34%), Gaps = 86/359 (23%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYF-LFTPLLPSAPVGTVDEKSIIEPIVN 113 +LILG+G S K K ++++I+ Y + P L I+ I Sbjct: 11 KILILGAGPAGFSAAKAALGKCDDITMINSEKYLPYYRPRLNEIIAKNKSIDDIL--IKK 68 Query: 114 FALKKKGNVTYYEAE-ATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYL 172 +K N+ +E ATSI+P+ VT+KS +IKY+ L Sbjct: 69 NDWYEKNNIKVITSEFATSIDPNNKLVTLKSGE--------------------KIKYEKL 108 Query: 173 ISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIV 232 I A G+ N +P + L ++L+I+ K G L+ Sbjct: 109 IIASGSIANKIKVPHADEI-FSLYSYDDALKIKD---ECKNKGKAFIIGGGILGIELAQA 164 Query: 233 VVGGG---PTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 ++ G G+ L+ + +D FL + + I + Y Sbjct: 165 IIDSGTPASIGIILEYPLERQLDRDGGLFLKDKLDRLGIKI-----------------YT 207 Query: 290 QSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITD 349 S+ E + I +I A G K + Sbjct: 208 NSNFEEMG------------------------------DLIRSSCVITAVGVKP-----N 232 Query: 350 LFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA--FAGLPPTAQVAHQEAEYLAKN 406 L + +SKRG+ VND ++ +I+A GD A + P +A+++ E N Sbjct: 233 LDFIKDTEIASKRGILVNDHMETS-IKDIYACGDVAEFYGKNPGLINIANKQGEVAGLN 290 >2YQU-A nrPDB Length = 455 Score = 64.5 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 55/352 (15%), Positives = 117/352 (33%), Gaps = 43/352 (12%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 ++L++G+G G V ++ T VG + K+++E Sbjct: 3 DLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGT----CLRVGCIPSKALLETTERI 58 Query: 115 ALKKKG----NVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 KKG V E + ++ ++ V + V L++ + Sbjct: 59 YEAKKGLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFLSERK 118 Query: 171 YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLS 230 L+ G E + + L ++ I + E+ + Sbjct: 119 VLVEETGEE---------LEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKR 169 Query: 231 IVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQ 290 ++VVGGG G+E G + + ++ ++E + +L + ++S A+ Sbjct: 170 LIVVGGGVIGLE-LGVVWHRL-------------GAEVIVLEYMDRILPTMDLEVSRAAE 215 Query: 291 SHLENTSIKVHLRTAVAKV--EEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVIT 348 + + + V V E K + + E + ++ A G + Sbjct: 216 RVFKKQGLTIRTGVRVTAVVPEAKGARVELEG------GEVLEADRVLVAVGRRPYTEGL 269 Query: 349 DLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEA 400 L + + + V++ L+ + +I+AIGD P A A +E Sbjct: 270 SL-ENAGLSTDERGRIPVDEHLRTR-VPHIYAIGDVVRG--PMLAHKASEEG 317 >2YAU-A nrPDB Length = 511 Score = 64.5 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 51/308 (16%), Positives = 87/308 (28%), Gaps = 52/308 (16%) Query: 100 GT-VDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQP---EN 155 G +D +S+ K V S+ D ++ Q Sbjct: 100 GWEMDRESLCPNWKTLIAAKNKVVNSINESYKSMFADTEGLSFHMGFGALQDAHTVVVRK 159 Query: 156 HLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKA 215 H + +Y++ A G+ P G+PG E Sbjct: 160 SEDPHSDVLETLDTEYILIATGSWPTRLGVPG------------------------DEFC 195 Query: 216 NLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALP 275 + ++ VGGG VE AG Y + + L Sbjct: 196 ITSNEAFYLEDAPKRMLCVGGGYIAVEFAGIFNGYKP--CGGY---------VDLCYRGD 244 Query: 276 IVLNMFEKKLSSYAQSHLENTSIKVHLR---TAVAKVEEKQLLAKTKHEDGKITEETIPY 332 ++L F+ ++ L I+V T + K E+ + Y Sbjct: 245 LILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITKNEDGSNHVHFNDGTEE------DY 298 Query: 333 GTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPT 392 ++ A G R L K + + V+ + + +NI+AIGD + Sbjct: 299 DQVMLAIGRVPRSQALQLDK-AGVRTGKNGAVQVDAYSKTS-VDNIYAIGDVTNRVM--L 354 Query: 393 AQVAHQEA 400 VA E Sbjct: 355 TPVAINEG 362 >5X1Y-B nrPDB Length = 554 Score = 64.5 bits (155), Expect = 1e-10, Method: Composition-based stats. Identities = 43/247 (17%), Positives = 81/247 (32%), Gaps = 41/247 (16%) Query: 160 HQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLP 219 + A++ + A GA P+ I G+ + Sbjct: 203 VEVNGAKLSAKRFLIATGASPSLPQISGLEKMDYL----------------------TST 240 Query: 220 KGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN 279 ++ + V+G G G+E G+L ++ +I L++ +L Sbjct: 241 TLLELKKIPKRLTVIGSGYIGME-LGQLFHHL-------------GSEITLMQRSERLLK 286 Query: 280 MFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWAT 339 ++ ++S + L I + +VE+ + + + + E I L+ AT Sbjct: 287 EYDPEISESVEKALIEQGINLVKGATFERVEQSGEIKRV-YVTVNGSREVIESDQLLVAT 345 Query: 340 GNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQE 399 G K +L + + +NDF Q I+A GD P VA E Sbjct: 346 GRKPNTDSLNL-SAAGVETGKNNEILINDFGQTSN-EKIYAAGDVTLG--PQFVYVAAYE 401 Query: 400 AEYLAKN 406 + N Sbjct: 402 GGIITDN 408 >4FX9-A nrPDB Length = 453 Score = 64.1 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 60/286 (20%), Positives = 107/286 (37%), Gaps = 43/286 (15%) Query: 101 TVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLH 160 V P V L + YY E + + V Y G Sbjct: 42 WVSHAPCGIPYVVEGLSTPDKLMYYPPEVFIKKRGIDLHLNAEVIEVDTGYVRVRENG-- 99 Query: 161 QAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEI-PNSLEIRRTFAANLEKANLLP 219 ++DYL+ A GA P I GV G F ++ P++L IR Sbjct: 100 --GEKSYEWDYLVFANGASPQVPAIEGVNLKGVFTADLPPDALAIREYM----------- 146 Query: 220 KGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN 279 E+ ++ ++V++GGG G+E A A + V +V ++ Sbjct: 147 ----EKYKVENVVIIGGGYIGIEMAEAFA------------AQGKNVT-MIVRGERVLRR 189 Query: 280 MFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWAT 339 F+K+++ + L+ + + L+ K+E ++ + K + G+ E +I AT Sbjct: 190 SFDKEVTDILEEKLKKH-VNLRLQEITMKIEGEERVEKVVTDAGEYKAE-----LVILAT 243 Query: 340 GNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 G K +L K++ + + N+ +Q N++A GD A Sbjct: 244 GIKPNI---ELAKQLGVRIGETGAIWTNEKMQTS-VENVYAAGDVA 285 >3O0H-A nrPDB Length = 484 Score = 64.1 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 73/203 (35%), Gaps = 23/203 (11%) Query: 215 ANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEAL 274 + + SIV+VGGG GVE A V+ L+ Sbjct: 178 CLTSNEIFDLEKLPKSIVIVGGGYIGVEFANIFH--------------GLGVKTTLLHRG 223 Query: 275 PIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGT 334 ++L F+ L + I + V++V+ + + +TI Sbjct: 224 DLILRNFDYDLRQLLNDAMVAKGISIIYEATVSQVQST----ENCYNVVLTNGQTICADR 279 Query: 335 LIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQ 394 ++ ATG L ++ + + + V++ + ++I+A+GD G Sbjct: 280 VMLATGRVPNTTGLGL-ERAGVKVNEFGAVVVDEKM-TTNVSHIWAVGDV--TGHIQLTP 335 Query: 395 VAHQEAEYLAKN-FDKMAQIPNF 416 VA +A KN F+ + P++ Sbjct: 336 VAIHDAMCFVKNAFENTSTTPDY 358 >3LAD-A nrPDB Length = 476 Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 39/189 (20%), Positives = 66/189 (34%), Gaps = 19/189 (10%) Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 + V+G G G+E ++ ++EA+ L +++++ Sbjct: 180 PGKLGVIGAGVIGLELGSVWARL--------------GAEVTVLEAMDKFLPAVDEQVAK 225 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 AQ L +K+ L V E K K D + + + LI A G + PV Sbjct: 226 EAQKILTKQGLKILLGARVTGTEVKNKQVTVKFVDAEGEKSQ-AFDKLIVAVGRR--PVT 282 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 407 TDL +RG D ++AIGD + A A +E +A+ Sbjct: 283 TDLLAADSGVTLDERGFIYVDDYCATSVPGVYAIGDVVRGAM--LAHKASEEGVVVAERI 340 Query: 408 DKMAQIPNF 416 N+ Sbjct: 341 AGHKAQMNY 349 >4JDR-A nrPDB Length = 474 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 63/369 (17%), Positives = 113/369 (30%), Gaps = 57/369 (15%) Query: 53 KPNVLILGSGWGAISF--------LKHIDTKKYN--------VSIISPRSYFLFTPLLPS 96 K V++LG+G S L+ + ++YN V I ++ ++ Sbjct: 6 KTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEE 65 Query: 97 APVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENH 156 A EP + + + +K ++ + + Sbjct: 66 AKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANTL 125 Query: 157 LGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKAN 216 + I +D I A G+ P +P + + + ++LE++ Sbjct: 126 EVEGENGKTVINFDNAIIAAGSRPI--QLPFIPHEDPRIWDSTDALELKEV--------- 174 Query: 217 LLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPI 276 ++V+GGG G+E QI +VE Sbjct: 175 -----------PERLLVMGGGIIGLEMGTVYHAL--------------GSQIDVVEMFDQ 209 Query: 277 VLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLI 336 V+ +K + + + L T V VE K+ E K E Y ++ Sbjct: 210 VIPAADKDIVKVFTKRISKK-FNLMLETKVTAVEAKEDGIYVTMEGKKAPAEPQRYDAVL 268 Query: 337 WATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVA 396 A G D K + + + V+ L+ +IFAIGD G P A Sbjct: 269 VAIGRVPNGKNLDAGK-AGVEVDDRGFIRVDKQLRT-NVPHIFAIGDI--VGQPMLAHKG 324 Query: 397 HQEAEYLAK 405 E A+ Sbjct: 325 VHEGHVAAE 333 >2QAE-A nrPDB Length = 468 Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 63/181 (34%), Gaps = 18/181 (9%) Query: 226 RRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKL 285 R ++VV+GGG G+E ++ +VE P ++ + Sbjct: 172 RVPKTMVVIGGGVIGLELGSVWARL--------------GAEVTVVEFAPRCAPTLDEDV 217 Query: 286 SSYAQSHL-ENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKAR 344 ++ L +N +K T V + E ET+ L+ + G + Sbjct: 218 TNALVGALAKNEKMKFMTSTKVVGGTNNGDSVSLEVEGKNGKRETVTCEALLVSVGRRPF 277 Query: 345 PVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLA 404 L K I + + + + D + +++AIGD G P A A E A Sbjct: 278 TGGLGLDK-INVAKNERGFVKIGDHFETS-IPDVYAIGDVVDKG-PMLAHKAEDEGVACA 334 Query: 405 K 405 + Sbjct: 335 E 335 >3LXD-A nrPDB Length = 415 Score = 63.3 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 58/263 (22%), Positives = 94/263 (35%), Gaps = 61/263 (23%) Query: 125 YEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFG 184 AE S++P +TV + SA I+Y LI A G +P Sbjct: 84 LGAEVVSLDPAAHTVKLGDGSA--------------------IEYGKLIWATGGDPRRLS 123 Query: 185 IPGVTDYG-HFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEA 243 G G H ++ ++ + A + + VV+GGG G+EA Sbjct: 124 CVGADLAGVHAVRTKEDADRLMAELDAGAK----------------NAVVIGGGYIGLEA 167 Query: 244 AGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQSHLENTSIKVHL 302 A L + V + L+EALP VL + + LS + Q+ + + Sbjct: 168 AAVLTKF--------------GVNVTLLEALPRVLARVAGEALSEFYQAEHRAHGVDLRT 213 Query: 303 RTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKR 362 A+ +E IP +I G P + L I S Sbjct: 214 GAAMDCIEGDGTKV---TGVRMQDGSVIPADIVIVGIGI--VPCVGAL---ISAGASGGN 265 Query: 363 GLAVNDFLQVKGSNNIFAIGDNA 385 G+ V++F + ++ ++AIGD A Sbjct: 266 GVDVDEFCRTSLTD-VYAIGDCA 287 >6AON-A nrPDB Length = 478 Score = 63.3 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 55/380 (14%), Positives = 126/380 (33%), Gaps = 42/380 (11%) Query: 51 SDKPNVLILGSGWGAISFLKHIDTKKYNVSIIS----PRSYFLFTPLLPSAPVGTVDEKS 106 S + +V+++G+G G ++ I + +S+ P VG + K+ Sbjct: 5 SKQFDVVVIGAGPGG--YIAAIRAAQLGMSVACIDAWQNGQGGPAPGGTCTNVGCIPSKA 62 Query: 107 IIEPIVNFALKKKGNVTY-YEAEATSINPD-----RNTVTIKSLSAVSQLYQPENHLGLH 160 +++ ++ + E + S+ D +NTV ++ + L++ H Sbjct: 63 LLQSSEHYEQANHHFAEHGIEVKGVSLKLDTLIGRKNTVVKQNNDGILYLFKKNKVTYFH 122 Query: 161 QAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPK 220 + D G + G TD K + + L Sbjct: 123 GKGAFAGQVD------GGWSI--KVTGTTDADLVAKHVIVATGSSARELPGLPFDEKNIL 174 Query: 221 GDPERRR----LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPI 276 + + V+G G G+E + ++ ++EA+P Sbjct: 175 SNDGALNIGAVPKKLGVIGAGVIGLEMGSVWRRL--------------GAEVTILEAMPE 220 Query: 277 VLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLI 336 L +++++ A + + + +++ + D K E+ + LI Sbjct: 221 FLAAADQQVAKEALKSFAKQGLDIQTGVKIGEIKAAAKSITVPYVDAKGAEQKLVVDKLI 280 Query: 337 WATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVA 396 + G + + + + + +AV++ + N++A+GD P A A Sbjct: 281 VSIGRVPYTGGLN-AEAVGLKLDERGFVAVDEDCKT-NLPNVWAVGDVVRG--PMLAHKA 336 Query: 397 HQEAEYLAKNFDKMAQIPNF 416 +E +A+ NF Sbjct: 337 EEEGVAVAERIAGQHGHVNF 356 >3L8K-A nrPDB Length = 466 Score = 62.2 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 55/243 (22%), Positives = 96/243 (39%), Gaps = 43/243 (17%) Query: 166 EIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPER 225 E + Y+I A GAE +PGV +Y +I R Sbjct: 130 EAETRYMIIASGAETAKLRLPGV-EYCLTSDDI-------------------FGYKTSFR 169 Query: 226 RRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKL 285 + +V++G G G+E A + VQ H++E L L E + Sbjct: 170 KLPQDMVIIGAGYIGLEIASIFRLM--------------GVQTHIIEMLDRALITLEDQD 215 Query: 286 SSYAQSHLENTSIKVHLR-TAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKAR 344 + +IK + T V K+++ + +DG ++++I +++ A G + Sbjct: 216 IVNTLLSILKLNIKFNSPVTEVKKIKDDEYEVIYSTKDG--SKKSIFTNSVVLAAGRR-- 271 Query: 345 PVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLA 404 PVI + ++I S K G+ V++ ++ N+FA GD GL P A + + A Sbjct: 272 PVIPEGAREIGLSIS-KTGIVVDETMKT-NIPNVFATGDA--NGLAPYYHAAVRMSIAAA 327 Query: 405 KNF 407 N Sbjct: 328 NNI 330 >3URH-A nrPDB Length = 491 Score = 62.2 bits (149), Expect = 5e-10, Method: Composition-based stats. Identities = 80/413 (19%), Positives = 134/413 (32%), Gaps = 74/413 (17%) Query: 27 STGVENSGAGPTSFKTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRS 86 S+GV+ G F++M D ++++GSG G V+++ RS Sbjct: 8 SSGVD-LGTENLYFQSMMAYD--------LIVIGSGPGGYVCAIKAAQLGMKVAVVEKRS 58 Query: 87 YFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKG------NVTYYEAEATSINPDRNTVT 140 + T VG + K+++ F + G V + + ++ Sbjct: 59 TYGGT----CLNVGCIPSKALLHASEMFHQAQHGLEALGVEVANPKLNLQKMMAHKDATV 114 Query: 141 IKSLSAVSQLYQPEN-----------HLGLHQAEPAEIKYDYL-----ISAVGAEPNTFG 184 ++ VS L++ G + + L + A G + G Sbjct: 115 KSNVDGVSFLFKKNKIDGFQGTGKVLGQGKVSVTNEKGEEQVLEAKNVVIATG--SDVAG 172 Query: 185 IPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAA 244 IPGV + T A LEK S++VVGGG G+E Sbjct: 173 IPGVEVA------FDEKTIVSSTGALALEKV------------PASMIVVGGGVIGLELG 214 Query: 245 GELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRT 304 ++ +VE L +L + +++ Q L I L Sbjct: 215 SVWARL--------------GAKVTVVEFLDTILGGMDGEVAKQLQRMLTKQGIDFKLGA 260 Query: 305 AVAKVEEKQLLAKTKHEDGKITE-ETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRG 363 V + AK E K E T+ ++ ATG K L K S+ Sbjct: 261 KVTGAVKSGDGAKVTFEPVKGGEATTLDAEVVLIATGRKPSTDGLGLAK-AGVVLDSRGR 319 Query: 364 LAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMAQIPNF 416 + ++ Q ++AIGD P A A E +A+ A N+ Sbjct: 320 VEIDRHFQTS-IAGVYAIGDVVRG--PMLAHKAEDEGVAVAEIIAGQAGHVNY 369 >1Q1R-A nrPDB Length = 431 Score = 61.4 bits (147), Expect = 8e-10, Method: Composition-based stats. Identities = 66/344 (19%), Positives = 114/344 (33%), Gaps = 76/344 (22%) Query: 55 NVLILGSGWGAIS--FLKHIDTKKYNVSIISPRSY--FLFTPLLPSAPVGTVDEKSIIEP 110 NV+I+G+G + F + N+ ++ + PL + G +S+ Sbjct: 6 NVVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVIPHHLPPLSKAYLAGKATAESLY-- 63 Query: 111 IVNFALKKKGNVTYYE-AEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKY 169 + N+ + T+IN DR V + A + Y Sbjct: 64 LRTPDAYAAQNIQLLGGTQVTAINRDRQQVILSDGRA--------------------LDY 103 Query: 170 DYLISAVGAEPNTFGIP----GVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPER 225 D L+ A G P + G + +L+ + ++ IRR A+ Sbjct: 104 DRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIADNR------------ 151 Query: 226 RRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKL 285 +VV+GGG G+E A A+ + + L++ VL Sbjct: 152 -----LVVIGGGYIGLEVAAT--------------AIKANMHVTLLDTAARVLERVTAPP 192 Query: 286 SSYAQSHLE-NTSIKVHLRTAVAKVE---EKQLLAKTKHEDGKITEETIPYGTLIWATGN 341 S HL + + T V E ++Q + EDG +P +I G Sbjct: 193 VSAFYEHLHREAGVDIRTGTQVCGFEMSTDQQKVTAVLCEDG----TRLPADLVIAGIGL 248 Query: 342 KARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 +L Q G+ +N+ +Q I A+GD A Sbjct: 249 IPNC---ELASAAGLQ--VDNGIVINEHMQTS-DPLIMAVGDCA 286 >2EQ6-A nrPDB Length = 464 Score = 61.0 bits (146), Expect = 1e-09, Method: Composition-based stats. Identities = 43/196 (21%), Positives = 78/196 (39%), Gaps = 21/196 (10%) Query: 224 ERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEK 283 E ++V+GGG G+E + ++ L+E +P +L + Sbjct: 165 EEGLPKRLLVIGGGAVGLELGQVYRRL--------------GAEVTLIEYMPEILPQGDP 210 Query: 284 KLSSYAQSHLENTSIKVHLRTAVAKVEEK--QLLAKTKHEDGKITEETIPYGTLIWATGN 341 + ++ + LE I+V +T E+K L + + +G EE + L+ A G Sbjct: 211 ETAALLRRALEKEGIRVRTKTKAVGYEKKKDGLHVRLEPAEGGEGEEVVVDKVLV-AVGR 269 Query: 342 KARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 K R L +K + + + VN ++ ++AIGD A P A A +E Sbjct: 270 KPRTEGLGL-EKAGVKVDERGFIRVNARMETS-VPGVYAIGDAARP--PLLAHKAMREGL 325 Query: 402 YLAKNFDKMAQIPNFQ 417 A+N ++Q Sbjct: 326 IAAENAAGKDSAFDYQ 341 >5U8W-A nrPDB Length = 481 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 46/234 (19%), Positives = 79/234 (33%), Gaps = 23/234 (9%) Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 + V+G G G+E ++ ++EAL L +++++ Sbjct: 184 PKKLGVIGAGVIGLELGSVWARL--------------GAEVTVLEALDKFLPAADEQIAK 229 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 A L + + L V E K+ D E+ + LI A G + PV Sbjct: 230 EALKVLTKQGLNIRLGARVTASEVKKKQVTVTFTDAN-GEQKETFDKLIVAVGRR--PVT 286 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 407 TDL +RG D +FAIGD + A A +E +A+ Sbjct: 287 TDLLAADSGVTLDERGFIYVDDHCKTSVPGVFAIGDVVRGAM--LAHKASEEGVMVAERI 344 Query: 408 DKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKY----NDLGALAYLGSERAIA 457 N+ S ++ + + K ++G + S RA+A Sbjct: 345 AGHKAQMNYDLIPSVIYTHPEIAWVGKTEQTLKAEGVEVNVGTFPFAASGRAMA 398 >5U25-A nrPDB Length = 602 Score = 59.5 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 51/137 (37%), Gaps = 4/137 (2%) Query: 270 LVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEET 329 +VE + ++ ++ L Q E + + T VE K+ E +E Sbjct: 332 VVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEP 391 Query: 330 IPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGL 389 Y ++ A G + +K + + + V+ ++ +I+AIGD G Sbjct: 392 QRYDAVLVAAGRAPNGKLIS-AEKAGVAVTDRGFIEVDKQMRT-NVPHIYAIGDI--VGQ 447 Query: 390 PPTAQVAHQEAEYLAKN 406 P A A E A+N Sbjct: 448 PMLAHKAVHEGHVAAEN 464 >1OJT-A nrPDB Length = 482 Score = 59.5 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 28/137 (20%), Positives = 51/137 (37%), Gaps = 4/137 (2%) Query: 270 LVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEET 329 +VE + ++ ++ L Q E + + T VE K+ E +E Sbjct: 213 VVEMMDGLMQGADRDLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEP 272 Query: 330 IPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGL 389 Y ++ A G + +K + + + V+ ++ +I+AIGD G Sbjct: 273 QRYDAVLVAAGRAPNGKLIS-AEKAGVAVTDRGFIEVDKQMRT-NVPHIYAIGDI--VGQ 328 Query: 390 PPTAQVAHQEAEYLAKN 406 P A A E A+N Sbjct: 329 PMLAHKAVHEGHVAAEN 345 >5TR3-A nrPDB Length = 481 Score = 59.5 bits (142), Expect = 3e-09, Method: Composition-based stats. Identities = 45/239 (18%), Positives = 79/239 (33%), Gaps = 23/239 (9%) Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 + V+G G G+E ++ ++EAL L + +S Sbjct: 184 PKRLGVIGAGVIGLELGSVWARL--------------GAEVTVLEALDTFLMAADTAVSK 229 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 AQ L + + L V + + + E+ I + LI A G + PV Sbjct: 230 EAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTY-TNAEGEQKITFDKLIVAVGRR--PVT 286 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 407 TDL +RG D ++AIGD + A A +E + + Sbjct: 287 TDLLASDSGVTIDERGYIFVDDYCATSVPGVYAIGDVVRGMM--LAHKASEEGIMVVERI 344 Query: 408 DKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKY----NDLGALAYLGSERAIATIRSG 462 N+ S ++ + + K ++G + S RA+A +G Sbjct: 345 KGHKAQMNYDLIPSVIYTHPEIAWVGKTEQALKAEGVEVNVGTFPFAASGRAMAANDTG 403 >6MO6-A nrPDB Length = 414 Score = 59.5 bits (142), Expect = 4e-09, Method: Composition-based stats. Identities = 59/326 (18%), Positives = 111/326 (34%), Gaps = 43/326 (13%) Query: 78 NVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRN 137 NV+I+ P + P+ G S P ++ G V + +A T +NPD+N Sbjct: 30 NVAIVEPSERHFYQPIWTLVGAGAKQLSSSGRPTA--SVIPSG-VEWIKARVTELNPDKN 86 Query: 138 TVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTD-YGHFLK 196 + H + +I Y YLI A+G + + I G+ + + H Sbjct: 87 CI--------------------HTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAH--- 123 Query: 197 EIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLR 256 +I ++ + D + + T V+ AG Q ++ Sbjct: 124 -----PKIGSNYSVKTVEKTWKALQDFKEGN----AIFTFPNTPVKCAGAPQKIMYLSEA 174 Query: 257 KFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLA 316 F + + KK + Q ++ ++ V+ + + +V + A Sbjct: 175 YFRKTGKRSKANIIFNTSLGAIFGV-KKYADALQEIIQERNLTVNYKKNLIEVRADKQEA 233 Query: 317 KTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSN 376 ++ D + I Y L D+ K P +++ + LQ + Sbjct: 234 VFENLDKPGETQVISYEML----HVTPPMSPPDVLKTSPVADAAGWVDVDKETLQHRRYP 289 Query: 377 NIFAIGDNAFAGLPPTAQVAHQEAEY 402 N+F IGD LP + A A+ Sbjct: 290 NVFGIGDC--TNLPTSKTAAAVAAQS 313 >5JCN-A nrPDB Length = 451 Score = 59.1 bits (141), Expect = 5e-09, Method: Composition-based stats. Identities = 42/236 (17%), Positives = 85/236 (36%), Gaps = 50/236 (21%) Query: 159 LHQAEPAEIKYDYLISAVGA---EPNTFGIPGVTDYGHF-LKEIPNSLEIRRTFAANLEK 214 L A A Y+ LI A G+ + + FG G L+E+ ++ ++ A Sbjct: 122 LTSAVGATFTYEILIIATGSSVIKLSDFGTQGADSNNILYLREVDDADKLVAAIQA---- 177 Query: 215 ANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEAL 274 ++ V+VGGG G+E + L+ + + +V Sbjct: 178 -----------KKGGKAVIVGGGYIGLELSAALK--------------INDFDVTMVFPE 212 Query: 275 PIVLN-MFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQ----LLAKTKHEDGKITEET 329 P + +F ++++ +S+ N +K+ T + K+ Sbjct: 213 PWCMPRLFTADIAAFYESYYTNKGVKIVKGTVAVGFDADANGDVTAVNLKN------GSV 266 Query: 330 IPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 + ++ G + +T LFK + K G+ + F + ++A+GD A Sbjct: 267 LEADIVVVGVGGRP---LTTLFKGQVAEE--KGGIKTDAFFETS-VPGVYAVGDVA 316 >1XDI-A nrPDB Length = 499 Score = 58.7 bits (140), Expect = 6e-09, Method: Composition-based stats. Identities = 59/379 (15%), Positives = 115/379 (30%), Gaps = 65/379 (17%) Query: 34 GAGPTSFKTMKVIDPQHSDKPNVLILG-SGWGAISFLKHIDTKKYNVSIISPRSYFLFTP 92 G GP ++ V H + V ++ G G + L K + I+ Sbjct: 9 GGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSK---TFIASTGLRTELR 65 Query: 93 LLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQ 152 P +D + + K T A++ I ++ ++ ++ +L Sbjct: 66 RAPHLGF-HIDFDDAKISLPQIHARVK---TLAAAQSADITAQLLSMGVQVIAGRGELID 121 Query: 153 PENHLGLH-------QAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIR 205 L H +E + D ++ A GA P +P++ Sbjct: 122 STPGLARHRIKATAADGSTSEHEADVVLVATGASPRI---------------LPSAQPDG 166 Query: 206 RTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEE 265 + +L D ++VVG G TG E + Sbjct: 167 ERILTWRQLYDLDALPD-------HLIVVGSGVTGAEFVDAYTEL--------------G 205 Query: 266 VQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQ---LLAKTKHED 322 V + +V + VL + + + +++ A V L+ T Sbjct: 206 VPVTVVASQDHVLPYEDADAALVLEESFAERGVRLFKNARAASVTRTGAGVLVTMTDGRT 265 Query: 323 GKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG 382 + + + G++ +G +++ Q L V+ + + I+A G Sbjct: 266 VEGSHALMTIGSVPNTSGLG--------LERVGIQLGRGNYLTVDRVSRTLAT-GIYAAG 316 Query: 383 DNAFAGLPPTAQVAHQEAE 401 D GL P A VA + Sbjct: 317 DC--TGLLPLASVAAMQGR 333 >6BZ0-A nrPDB Length = 480 Score = 58.3 bits (139), Expect = 8e-09, Method: Composition-based stats. Identities = 48/262 (18%), Positives = 83/262 (31%), Gaps = 41/262 (15%) Query: 160 HQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLP 219 H+ E ++ Y+I A G+ P IP + + + N Sbjct: 137 HEGETQILEPKYVILASGSVPV---------------NIPVAPVDQDIIVDSTGALNFPE 181 Query: 220 KGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN 279 + V+G G G+E + ++ + EA+ L Sbjct: 182 V-------PKRLGVIGAGVIGLELGSVWRRL--------------GAEVVVFEAMDAFLP 220 Query: 280 MFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWAT 339 M +K LS Q L + + + V+ E K+ +E + LI Sbjct: 221 MADKALSKEYQKILTKQGLDIRIGAKVSGTEVNGREVTVKYTQAGEDKEQ-TFDKLIVCV 279 Query: 340 GNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQE 399 G KA L + + + + + VND ++AIGD P A A +E Sbjct: 280 GRKAYAE-GLLAEDSGIKLTERGLVEVNDHC-ATSVEGVYAIGDLVRG--PMLAHKAMEE 335 Query: 400 AEYLAKNFDKMAQIPNFQKNLS 421 + A N+ +S Sbjct: 336 GVMAVERIHGHAAQVNYDTIIS 357 >3II4-A nrPDB Length = 466 Score = 57.5 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 62/360 (17%), Positives = 121/360 (33%), Gaps = 40/360 (11%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 +V++LG+G G + +I+ P+ + VG + K+++ Sbjct: 7 DVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGV-----CLNVGCIPSKALLRNAELV 61 Query: 115 ALKKKGNVTY-YEAEAT---SINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 + K + E T I DR+ + A +N + + Sbjct: 62 HIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEIHGYGTFADAN 121 Query: 171 YLISAV---GAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRR 227 L+ + G E TF + G + +P + + E+ R Sbjct: 122 TLLVDLNDGGTESVTFD-NAIIATGSSTRLVPGT-SLSANVVTYEEQ-------ILSREL 172 Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSS 287 SI++ G G G+E L++Y V + +VE LP L + +S Sbjct: 173 PKSIIIAGAGAIGMEFGYVLKNY--------------GVDVTIVEFLPRALPNEDADVSK 218 Query: 288 YAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 + + + + T V + + T + + ++ A G Sbjct: 219 EIEKQFKKLGVTILTATKVESIADGGSQV-TVTVTKDGVAQELKAEKVLQAIGFAPNVEG 277 Query: 348 TDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNF 407 L K + ++ + V+D+++ +I+AIGD GL A VA + A+ Sbjct: 278 YGLDK-AGVALTDRKAIGVDDYMRT-NVGHIYAIGDV--NGLLQLAHVAEAQGVVAAETI 333 >1ONF-A nrPDB Length = 500 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 42/270 (15%), Positives = 93/270 (34%), Gaps = 57/270 (21%) Query: 117 KKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAV 176 K V YE A+ ++ N + IK + + + + ++ AV Sbjct: 99 LSKDKVDLYEGTASFLS--ENRILIKGTKDNNNKDNGPLNEEILEGRN-------ILIAV 149 Query: 177 GAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGG 236 G +P + G+ + +S E F E I +VG Sbjct: 150 GNKPVFPPVKGI-------ENTISSDE----FFNIKESKK--------------IGIVGS 184 Query: 237 GPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENT 296 G VE ++ + ++ +L F++ + + ++ ++ Sbjct: 185 GYIAVELINVIKRL--------------GIDSYIFARGNRILRKFDESVINVLENDMKKN 230 Query: 297 SIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETI--PYGTLIWATGNKARPVITDLFKKI 354 +I + V ++++ K+ +++ I + +I+ G L K Sbjct: 231 NINIVTFADVVEIKK----VSDKNLSIHLSDGRIYEHFDHVIYCVGRSPDTENLKLEKLN 286 Query: 355 PEQNSSKRGLAVNDFLQVKGSNNIFAIGDN 384 E N++ + V++ + NNI+A+GD Sbjct: 287 VETNNNY--IVVDENQRTS-VNNIYAVGDC 313 >5J5Z-A nrPDB Length = 496 Score = 55.6 bits (132), Expect = 5e-08, Method: Composition-based stats. Identities = 41/180 (22%), Positives = 65/180 (36%), Gaps = 23/180 (12%) Query: 225 RRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLN-MFEK 283 ++ +VV+G G GVE G + + D + VE L V + Sbjct: 197 KKVPEKMVVIGAGVIGVE-LGSVWQRLGAD-------------VTAVEFLGHVGGVGIDM 242 Query: 284 KLSSYAQSHLENTSIKVHLRTAV---AKVEEKQLLAKTKHEDGKITEETIPYGTLIWATG 340 ++S Q L+ K L T V K + ++ + G E I L+ G Sbjct: 243 EISKNFQRILQKQGFKFKLNTKVTGATKKSDGKIDVSIEAASGGKAE-VITCDVLLVCIG 301 Query: 341 NKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEA 400 + L +++ + + + VN Q K NI+AIGD P A A E Sbjct: 302 RRPFTKNLGL-EELGIELDPRGRIPVNTRFQTK-IPNIYAIGDVVAG--PMLAHKAEDEG 357 >4DNA-A nrPDB Length = 463 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 31/188 (16%), Positives = 59/188 (31%), Gaps = 21/188 (11%) Query: 213 EKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVE 272 E + SI++ GGG VE A V+ L+ Sbjct: 155 ELCITSNEAFDLPALPESILIAGGGYIAVEFANIFH--------------GLGVKTTLIY 200 Query: 273 ALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPY 332 +L+ F++ + + +E I++ + V A + + I Sbjct: 201 RGKEILSRFDQDMRRGLHAAMEEKGIRILCEDIIQSV---SADADGRRVATTMKHGEIVA 257 Query: 333 GTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPT 392 ++ A G L + + + + V+ F + + I+A+GD Sbjct: 258 DQVMLALGRMPNTNGLGL-EAAGVRTNELGAIIVDAFSRTS-TPGIYALGDV--TDRVQL 313 Query: 393 AQVAHQEA 400 VA EA Sbjct: 314 TPVAIHEA 321 >4EMJ-A nrPDB Length = 410 Score = 52.9 bits (125), Expect = 3e-07, Method: Composition-based stats. Identities = 53/336 (15%), Positives = 121/336 (36%), Gaps = 67/336 (19%) Query: 56 VLILGSGWGAISFLKHIDTKKYN--VSIISPRSYF-LFTPLLPSAPV-GTVDEKSIIEPI 111 V I+G+G G + + + + + +S+I + P L A + G+++ I+ Sbjct: 5 VAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLPYDRPSLSKAVLDGSLERPPILAEA 64 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDY 171 + + +T E T+++ T+++ + +S D Sbjct: 65 DWYGEARIDMLT--GPEVTALDVQTRTISLDDGTTLSA--------------------DA 102 Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 ++ A G+ T +PG ++P + +R + + + + Sbjct: 103 IVIATGSRARTMALPG--------SQLPGVVTLRTYGDVQVLRDSWTSATR--------L 146 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL-NMFEKKLSSYAQ 290 ++VGGG G E A + + + ++EA +L + +++ ++ + Sbjct: 147 LIVGGGLIGCEVATTARKL--------------GLSVTILEAGDELLVRVLGRRIGAWLR 192 Query: 291 SHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDL 350 L ++V L T V + L + DG+ + + + G + + Sbjct: 193 GLLTELGVQVELGTGVVGFSGEGQLEQVMASDGR----SFVADSALICVGAEPADQLAR- 247 Query: 351 FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAF 386 + RG+ V D + +FA+GD A Sbjct: 248 ----QAGLACDRGVIV-DHCGATLAKGVFAVGDVAS 278 >1V59-A nrPDB Length = 478 Score = 52.5 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 31/138 (22%), Positives = 58/138 (42%), Gaps = 9/138 (6%) Query: 267 QIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVA--KVEEKQLLAKTKHEDGK 324 ++ +VE P + + +++ Q L+ + L T V K + + + + ED K Sbjct: 208 KVTVVEFQPQIGASMDGEVAKATQKFLKKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTK 267 Query: 325 ITEET-IPYGTLIWATGNKARPVITDL-FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIG 382 ++ + L+ A G + P I L +KI + + L ++D K +I +G Sbjct: 268 TNKQENLEAEVLLVAVGRR--PYIAGLGAEKIGLEVDKRGRLVIDDQFNSK-FPHIKVVG 324 Query: 383 DNAFAGLPPTAQVAHQEA 400 D F P A A +E Sbjct: 325 DVTFG--PMLAHKAEEEG 340 >5KVH-A nrPDB Length = 543 Score = 52.2 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 58/250 (23%), Positives = 91/250 (36%), Gaps = 37/250 (14%) Query: 139 VTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGHFLKEI 198 V + + V QL +N + L+ ++I Y+ + A G P + + G +K Sbjct: 149 VAVLTGKKVVQLDVRDNMVKLNDG--SQITYEKCLIATGGTPR--SLSAIDRAGAEVKSR 204 Query: 199 PNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKF 258 F +LEK + R + SI ++GGG G E A L Sbjct: 205 TTLFRKIGDFR-SLEKIS---------REVKSITIIGGGFLGSELACALGRKA------- 247 Query: 259 LPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAV--AKVEEKQLLA 316 AL EV I L + + + LS++ + +KV V V +LL Sbjct: 248 -RALGTEV-IQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKLLI 305 Query: 317 KTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSK-RGLAVNDFLQVKGS 375 K K + ++ A G + +L K + S G VN LQ + Sbjct: 306 KLKD------GRKVETDHIVAAVGLEPNV---ELAKTGGLEIDSDFGGFRVNAELQARS- 355 Query: 376 NNIFAIGDNA 385 NI+ GD A Sbjct: 356 -NIWVAGDAA 364 >4YRY-B nrPDB Length = 468 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 62/340 (18%), Positives = 111/340 (32%), Gaps = 47/340 (13%) Query: 51 SDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEP 110 S K V ++GSG ++ + Y+V I P G + + Sbjct: 138 SKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEA----------FHKPGGVL-----VYG 182 Query: 111 IVNFALKKK---GNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEI 167 I F L K+ V+Y +N NTV K++ L Sbjct: 183 IPEFRLPKRIVEREVSYIRK--LGVNFHLNTVVGKTVKVKELL----------------S 224 Query: 168 KYDYLISAVGA-EPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 226 +YD + GA P GIPG G + + NL KA L P+ D R Sbjct: 225 EYDAVFIGTGAGTPKFMGIPGTNLNGVYSANEFLTR-------VNLMKAYLFPEYDTPIR 277 Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 + V+G G T ++AA + + E+ E + E Sbjct: 278 VGKKVAVIGAGNTAMDAARSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWL 337 Query: 287 SYAQSHLENTSIKVHLRTAV-AKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARP 345 + ++ + + V V +++E + + + + + +I A G Sbjct: 338 TLPIRYIGDANGNVEAMECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNR 397 Query: 346 VITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNA 385 V+ L + + + + + ++ +FA GD Sbjct: 398 VL--LSEFPGLELNERGYIKADEDTGATSVKGVFAGGDIV 435 Score = 36.0 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 35/175 (20%), Positives = 59/175 (33%), Gaps = 16/175 (9%) Query: 209 AANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQI 268 A NLE+ G + + + VVG GP G+ AA +L + + F + Sbjct: 125 AENLEEDVKPLAGSKKEK----VAVVGSGPAGLTAAADLA-KMGYHVDIF--EAFHKPGG 177 Query: 269 HLVEALPIV-LNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITE 327 LV +P L K++ S++ + HL T V K + + L T Sbjct: 178 VLVYGIPEFRLP---KRIVEREVSYIRKLGVNFHLNTVVGKTVKVKELLSEYDAVFIGTG 234 Query: 328 ETIPYGTLIWATGNKARPVITDLFKKIPEQNS-----SKRGLAVNDFLQVKGSNN 377 P I T + ++ + + V + V G+ N Sbjct: 235 AGTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGN 289 >3F8P-A nrPDB Length = 323 Score = 49.1 bits (115), Expect = 4e-06, Method: Composition-based stats. Identities = 56/342 (16%), Positives = 116/342 (33%), Gaps = 70/342 (20%) Query: 52 DKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPI 111 +K +V+I+G G A Y ++ S R Y L T ++ P G + E I++ Sbjct: 14 EKFDVIIVGLGPAA-----------YGAALYSAR-YMLKTLVIGETPGGQLTEAGIVD-- 59 Query: 112 VNFALKKKGNVTYYEAEATSINPDRNTVTIKS-----LSAVSQLYQPENHLGLHQAEPAE 166 + E +A+ + N K L V ++ + + E Sbjct: 60 --------DYLGLIEIQASDMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGE 111 Query: 167 IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 226 K D +I +G + G+PG ++ + D Sbjct: 112 FKADSVILGIGVKRRKLGVPGEQEFA-------------------GRGISYCSVCDAPLF 152 Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 + + V+GGG + +E A L Y + + I Sbjct: 153 KNRVVAVIGGGDSALEGAEILSSYSTKVYLIHRRDTFKAQPI------------------ 194 Query: 287 SYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITE-ETIPYGTLIWATGNKARP 345 Y ++ + +++ L + V +++ +++ + E+ K E + + + G Sbjct: 195 -YVETVKKKPNVEFVLNSVVKEIKGDKVVKQVVVENLKTGEIKELNVNGVFIEIGFDPP- 252 Query: 346 VITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFA 387 TD K + + + V+++++ +FA GD A Sbjct: 253 --TDFAKSNGIETDTNGYIKVDEWMRTS-VPGVFAAGDCTSA 291 >5VJ7-A nrPDB Length = 476 Score = 49.1 bits (115), Expect = 5e-06, Method: Composition-based stats. Identities = 73/372 (19%), Positives = 115/372 (30%), Gaps = 81/372 (21%) Query: 54 PNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVN 113 V I+G+G ++ + Y V+I P G + + Sbjct: 155 KKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL----------HQPGGVLTYGIPEFRLPK 204 Query: 114 FALKKK-GNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYL 172 L+K+ ++ E + + T+TI+ L +YD + Sbjct: 205 EILRKELKKLSLLGVEIKTDHIVGKTITIQELLQ---------------------EYDAV 243 Query: 173 ISAVGA-EPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 GA P IPG+ G + + NL KA P+ D + Sbjct: 244 FIGTGAGTPKLPNIPGINLNGIYSANEFLTR-------INLMKAYKFPEYDTPIVVGKKV 296 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 291 VV+G G T ++AA + L EV I + E+ Sbjct: 297 VVIGAGNTAMDAA------------RSALRLGAEVTIAYRRGREDMTARIEE------VK 338 Query: 292 HLENTSIKVH-LRTAVAKV-EEKQLLAKTKHEDGKITEE----------------TIPYG 333 H E +K V + +E + K E K EE T+ Sbjct: 339 HAEEEGVKFMFFVNPVEFIGDENGNVKAVKFEKMKPLEERDSRGKRKIVGTGEYITVEAD 398 Query: 334 TLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTA 393 T+I A G V L++ PE + G V D + +FA GD T Sbjct: 399 TVIIAIGQTPNKV---LWRATPELKVDEWGRIVVDENLMTSIPGVFAGGDAIRG--EATV 453 Query: 394 QVAHQEAEYLAK 405 +A + AK Sbjct: 454 ILAMGDGRKAAK 465 >1ZK7-A nrPDB Length = 467 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 30/220 (13%), Positives = 64/220 (29%), Gaps = 48/220 (21%) Query: 167 IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERR 226 + +D + A GA P IPG+ + ++ + Sbjct: 137 VMFDRCLVATGASPAVPPIPGLKESPYW----------------------TSTEALASDT 174 Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 + V+G +E A L +V + A + + + Sbjct: 175 IPERLAVIGSSVVALELAQAFA------------RLGSKVTVL---ARNTLFFREDPAIG 219 Query: 287 SYAQSHLENTSIKV--HLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKAR 344 + I+V H + + + + + T H + L+ ATG Sbjct: 220 EAVTAAFRAEGIEVLEHTQASQVAHMDGEFVLTTTH-------GELRADKLLVATGRTPN 272 Query: 345 PVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDN 384 L +++ + ++ ++ NI+A GD Sbjct: 273 TRSLALD-AAGVTVNAQGAIVIDQGMRTSN-PNIYAAGDC 310 >1FL2-A nrPDB Length = 310 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 100/298 (33%), Gaps = 50/298 (16%) Query: 108 IEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAE- 166 I N+ K A A ++ D V + + S+L GLHQ E A Sbjct: 41 TVDIENYISVPKTEGQKL-AGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASG 99 Query: 167 --IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPE 224 +K +I A GA+ +PG Y + P D Sbjct: 100 AVLKARSIIVATGAKWRNMNVPGEDQYR-------------------TKGVTYCPHCDGP 140 Query: 225 RRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKK 284 + + V+GGG +GVEAA +L V + L+E P + ++ Sbjct: 141 LFKGKRVAVIGGGNSGVEAAIDLAGIVEH--------------VTLLEFAPEMKA--DQV 184 Query: 285 LSSYAQSHLENTSIKVHLRTAVAKVEEKQLL-AKTKHEDGKITEETIPYGTLIWATGNKA 343 L +S L+N I ++ +T K + +++ + + G + G Sbjct: 185 LQDKLRS-LKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFV-QIGLLP 242 Query: 344 RPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 T+ + E+N + ++ + +FA GD P Q+ E Sbjct: 243 N---TNWLEGAVERNRM-GEIIIDAKCET-NVKGVFAAGDCTTV---PYKQIIIATGE 292 >4YKF-A nrPDB Length = 521 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 58/298 (19%), Positives = 100/298 (33%), Gaps = 50/298 (16%) Query: 108 IEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAE- 166 I N+ K A A ++ D V + + S+L GLHQ E A Sbjct: 252 TVDIENYISVPKTEGQKL-AGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASG 310 Query: 167 --IKYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPE 224 +K +I A GA+ +PG Y + P D Sbjct: 311 AVLKARSIIVATGAKWRNMNVPGEDQYR-------------------TKGVTYCPHCDGP 351 Query: 225 RRRLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKK 284 + + V+GGG +GVEAA +L V + L+E P + ++ Sbjct: 352 LFKGKRVAVIGGGNSGVEAAIDLAGIVEH--------------VTLLEFAPEMKA--DQV 395 Query: 285 LSSYAQSHLENTSIKVHLRTAVAKVEEKQLL-AKTKHEDGKITEETIPYGTLIWATGNKA 343 L +S L+N I ++ +T K + +++ + + G + G Sbjct: 396 LQDKLRS-LKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGIFV-QIGLLP 453 Query: 344 RPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAE 401 T+ + E+N + ++ + +FA GD P Q+ E Sbjct: 454 N---TNWLEGAVERNRM-GEIIIDAKCET-NVKGVFAAGDCTTV---PYKQIIIATGE 503 >5JFC-L nrPDB Length = 474 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 62/359 (17%), Positives = 112/359 (31%), Gaps = 56/359 (15%) Query: 54 PNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVN 113 V I+G+G ++ + Y V+I P G + I I Sbjct: 155 KKVAIIGAGPAGLTCAADLAKMGYEVTIYEAL----------HQPGGVL-----IYGIPE 199 Query: 114 FALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLI 173 F L K + E ++ + L + ++ +YD + Sbjct: 200 FRLPK----EIVKKELENLRRLGVKIETNVLVGKTITFEE-----------LREEYDAIF 244 Query: 174 SAVGA-EPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIV 232 GA P + PGV G + + NL KA P+ D + + Sbjct: 245 IGTGAGTPRIYPWPGVNLNGIYSANEFLTR-------INLMKAYKFPEYDTPIKVGKRVA 297 Query: 233 VVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSH 292 V+GGG T ++AA + ++ +E+ E + + Sbjct: 298 VIGGGNTAMDAARS-ALRLGAEVWILYRRTRKEMTAREEEIKHAEEEGVKFMFLVTPKRF 356 Query: 293 LENTSIKVHLRTAVAKVEEKQLLAKTKHEDGK----ITEET--IPYGTLIWATGNKARPV 346 + + + + +E +++ E G+ T ET + + T I A G Sbjct: 357 IGDENGNLK------AIELEKMKLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQTPNK- 409 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAK 405 + +P + G V D + +FA GD T +A + AK Sbjct: 410 --TFLETVPGLKVDEWGRIVVDENLMTSIPGVFAGGDAIRG--EATVILAMGDGRKAAK 464 >1F6M-A nrPDB Length = 320 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 50/338 (14%), Positives = 96/338 (28%), Gaps = 63/338 (18%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 +LILGSG + + +I+ D + P++ Sbjct: 7 KLLILGSGPAGYTAAVYAARANLQPVLITGMEKGGQLTTTTEVENWPGDPNDLTGPLL-- 64 Query: 115 ALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLIS 174 + AT + I + ++ ++ + E D LI Sbjct: 65 -------MERMHEHATKFETEIIFDHINKVDLQNRPFR-------LNGDNGEYTCDALII 110 Query: 175 AVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVV 234 A GA G+P ++ + + S F N + + V+ Sbjct: 111 ATGASARYLGLP--SEEAFKGRGVSASATCDGFFYRNQK-----------------VAVI 151 Query: 235 GGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLE 294 GGG T VE A L + + +I + + V E Sbjct: 152 GGGNTAVEEALYLSNIASEVHLIHRRDGFRAEKILIKRLMDKV----------------E 195 Query: 295 NTSIKVHLRTAVAKV--EEKQLL-AKTKHEDGKITEETIPYGTLIWATGNKARPVITDLF 351 N +I +H + +V ++ + + + E++ L A G+ I + Sbjct: 196 NGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIESLDVAGLFVAIGHSPNTAIFE-- 253 Query: 352 KKIPEQNSSKRGLAVNDFL----QVKGSNNIFAIGDNA 385 + + V + +FA GD Sbjct: 254 ---GQLELENGYIKVQSGIHGNATQTSIPGVFAAGDVM 288 >2VDC-G nrPDB Length = 456 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 25/173 (14%), Positives = 56/173 (32%), Gaps = 36/173 (20%) Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 +VV+GGG T ++ ++ + + +++++ Sbjct: 266 HVVVLGGGDTAMDCVRTAIRQGATSVKCLYRRDRKN------------MPGSQREVA--- 310 Query: 290 QSHLENTSIKVHLR---------TAVAKVEEKQLLAKTKHEDGKITEETI-------PYG 333 H E ++ + T V V ++ G+ T + I Sbjct: 311 --HAEEEGVEFIWQAAPEGFTGDTVVTGVRAVRIHLGVADATGRQTPQVIEGSEFTVQAD 368 Query: 334 TLIWATGNKARPVITDLFKKIPEQNSSK-RGLAVNDFLQVKGSNNIFAIGDNA 385 +I A G + + + PE ++ L V+ ++ + +FA GD Sbjct: 369 LVIKALGFEPEDLPNAFDE--PELKVTRWGTLLVDHRTKMTNMDGVFAAGDIV 419 >5M5J-A nrPDB Length = 325 Score = 37.9 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 20/101 (19%), Positives = 45/101 (44%), Gaps = 4/101 (3%) Query: 286 SSYAQSHLENTSIKVHLRTAVAKVE-EKQLLAKTKHEDGKITE-ETIPYGTLIWATGNKA 343 ++ + + I++ +A+ +++ + + + ++ K + T+ G L WA G+ Sbjct: 197 AAMVKKVMNEKLIEIIYDSAIDEIKGDGKCVTSVSIKNLKDGKTRTLNAGALYWAVGH-- 254 Query: 344 RPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDN 384 P + L K EQ+ + L + Q + +FA GD Sbjct: 255 DPQTSFLKKGQLEQDEAGYILLKDHPTQRTSVDGVFAAGDC 295 >3IC9-A nrPDB Length = 492 Score = 37.1 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 37/213 (17%), Positives = 67/213 (31%), Gaps = 40/213 (18%) Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 ++ A G+ PN + + L NL D S+ Sbjct: 140 IVIATGSRPNYPEF------------------LAAAGSRLLTNDNLFELNDL----PKSV 177 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 291 V G G G+E L V + + V N+ ++++ YA+ Sbjct: 178 AVFGPGVIGLELGQALSRL--------------GVIVKVFGRSGSVANLQDEEMKRYAEK 223 Query: 292 HLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDL- 350 N + V EK+ + + D + T + ++ ATG KA + L Sbjct: 224 TF-NEEFYFDAKARVISTIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKAN--VDKLG 280 Query: 351 FKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 + + K ++ ++IF GD Sbjct: 281 LENTSIELDKKNSPLFDELTLQTSVDHIFVAGD 313 >5UWY-A nrPDB Length = 308 Score = 35.2 bits (79), Expect = 0.075, Method: Composition-based stats. Identities = 56/331 (16%), Positives = 104/331 (31%), Gaps = 66/331 (19%) Query: 57 LILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFAL 116 LI+GSG ++ + +V+II AP G ++ I N+ Sbjct: 8 LIIGSGPAGMTAALYAARSNLSVAIIEQ-----------GAPGGQMNN---TFDIENYP- 52 Query: 117 KKKGNVTYYEAE-ATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISA 175 G E A + ++++ + Q + E A + +I A Sbjct: 53 ---GYDHISGPELAMKMYEPLEKFNVENIYGIVQKIENFGDYKCVLTEDASYEAKTVIIA 109 Query: 176 VGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVG 235 GA+ G+PG +Y + + + + D R ++VVG Sbjct: 110 TGAKYRVLGVPG-EEY-YTSRGV-----------------SYCAVCDGAFFRDQDLLVVG 150 Query: 236 GGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLEN 295 GG + VE A L + + +I N Sbjct: 151 GGDSAVEEAIYLTQFAKKVTVVHRRDQLRAQKI-------------------LQDRAFAN 191 Query: 296 TSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPY---GTLIWATGNKARPVITDLFK 352 + + V +++ + + T + + G I+ N ++ DL Sbjct: 192 DKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFIYVGMNPVTGMVKDL-- 249 Query: 353 KIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 E S+ + +D ++ IFAIGD Sbjct: 250 ---EITDSEGWIITDDHMRTS-IPGIFAIGD 276 >5N1T-A nrPDB Length = 429 Score = 34.4 bits (77), Expect = 0.13, Method: Composition-based stats. Identities = 51/331 (15%), Positives = 98/331 (29%), Gaps = 49/331 (14%) Query: 68 FLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEA 127 +L+H D V++I+P + P G D SI + L+ V + Sbjct: 55 YLRHFD-PDLEVTLINPSDTYTTCPFSNLVLGGERDLASITHDLSQ--LEHHHGVRLVQR 111 Query: 128 EATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPG 187 SI+ D + V + SA I YD L+ + G + + G Sbjct: 112 WVESIDADGHRVVLDDGSA--------------------IGYDRLVVSPGIDLRWDAVEG 151 Query: 188 VTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGEL 247 + +P++ LL + E +VV+ Sbjct: 152 YDQAAQ--EAMPHAWRPGEQ--------TLLLRRQLEAMSDGGVVVIAPPANPFRCPPGP 201 Query: 248 QDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVA 307 + + +L +I +++A ++A+ L T + + Sbjct: 202 YERA-SLIAHYLKHHKPRSKILILDAKD-----------AFAKQGLFQTGWETLYPGMIE 249 Query: 308 KVE--EKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLA 365 V E + + G++ + Y + + + + S Sbjct: 250 WVPGIEGGTVERVDAATGEVFTPSGRYRGDV--VNLIPPQHAGAIARNTGLTDDSGWCPV 307 Query: 366 VNDFLQVKGSNNIFAIGDNAFAGLPPTAQVA 396 + +I IGD + AG P A A Sbjct: 308 NQQTFESLQIPHIHVIGDASIAGAMPKAGFA 338 >5U63-A nrPDB Length = 321 Score = 34.0 bits (76), Expect = 0.17, Method: Composition-based stats. Identities = 39/220 (17%), Positives = 64/220 (29%), Gaps = 42/220 (19%) Query: 170 DYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 D LI A GA G+P +Y R +A + P Sbjct: 110 DALIIATGASARYIGLPSEENYK------------GRGVSACATCDGFFYRNKP------ 151 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 + V+GGG T VE A L + +I L Sbjct: 152 -VGVIGGGNTAVEEALYLANIASTVHLIHRRDSFRAEKI----------------LIDRL 194 Query: 290 QSHLENTSIKVHLRTAVAKV--EEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVI 347 +E I +H + +V + + +E + L A G+ Sbjct: 195 YKKVEEGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKEELKLDGLFVAIGHSPN--- 251 Query: 348 TDLFKKIPEQNSSKRGLA--VNDFLQVKGSNNIFAIGDNA 385 T++F+ E N+ + ++ +FA GD Sbjct: 252 TEIFQGQLELNNGYIVVKSGLDGNATATSVEGVFAAGDVM 291 >6BWT-A nrPDB Length = 319 Score = 33.3 bits (74), Expect = 0.29, Method: Composition-based stats. Identities = 61/345 (17%), Positives = 110/345 (31%), Gaps = 70/345 (20%) Query: 51 SDKPNVLILGSGWGAIS---FLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSI 107 ++ ++ILGSG + + + K ++ + P T Sbjct: 5 ANHHKLIILGSGPAGYTAAIYAARANLKPVIITGMQPGGQLTTTT------------DVY 52 Query: 108 IEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEI 167 P + + + +A + TI ++ ++ ++ E + Sbjct: 53 NWPGEPDGIMGPELMEKLQKQAERFDTQIVYDTINAVDLQNKPFK-------LVGEVEQY 105 Query: 168 KYDYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRR 227 D LI A GA G+ ++ K + F N + Sbjct: 106 TCDTLIIATGATAKYLGLE--SEEKFMGKGVSACATCDGFFYKNKD-------------- 149 Query: 228 LLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQ-IHLVEALPIVLNMFEKKLS 286 + VVGGG T VE A FL +A+ V IH + L EK L Sbjct: 150 ---VAVVGGGNTAVEEA------------LFLSNIAKSVTLIHRRDTLRS-----EKILI 189 Query: 287 SYAQSHLENTSIKVHLRTAVAKV--EEKQL-LAKTKHEDGKITEETIPYGTLIWATGNKA 343 ++ +I + T + +V ++ + + K+ + G I A G+ Sbjct: 190 DKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQMGVAGVFI-AIGHTP 248 Query: 344 RPVITDLFKKIPEQNS---SKRGLAVNDFLQVKGSNNIFAIGDNA 385 I ++ +N K GLA + +FA GD A Sbjct: 249 NTSI--FAGQLEMENGYIKVKSGLAGDATQ--TNIKGVFAAGDVA 289 >1FCD-A nrPDB Length = 401 Score = 32.5 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 22/116 (18%), Positives = 35/116 (30%), Gaps = 23/116 (19%) Query: 78 NVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRN 137 V++I P + + L G +SI + + + AT I+PD+ Sbjct: 29 EVTLIEPNTDYYTCYLSNEVIGGDRKLESIKH---GYDGLRAHGIQVVHDSATGIDPDKK 85 Query: 138 TVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVTDYGH 193 V AE YD + A G E I G ++ Sbjct: 86 LVKTAGG--------------------AEFGYDRCVVAPGIELIYDKIEGYSEEAA 121 >6GAS-A nrPDB Length = 331 Score = 32.5 bits (72), Expect = 0.49, Method: Composition-based stats. Identities = 38/185 (20%), Positives = 70/185 (37%), Gaps = 23/185 (12%) Query: 224 ERRRLLSIVVVGGGPTGV---------EAAGELQDYVHQDLRKFLPALAEEVQIHLVEAL 274 E +++ I ++GGGPTG+ +A+ ++ + + Q + L AL E I+ V Sbjct: 5 ENQKVYDITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQ-LSALYPEKYIYDVAGF 63 Query: 275 PIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGT 334 P V ++L + ++ V L AV +E+ + +T + Y Sbjct: 64 PKVR---AQELVDNLKEQMKKFDPTVCLEEAVDTLEK-----QADGIFKLVTNKQTHYSK 115 Query: 335 LIWATGNKARPVITDL-FKKIPEQNSSKRGLAVNDFLQVKGSN-NIFAIGDNA---FAGL 389 + T L + + V+D + G +F GD+A L Sbjct: 116 SVIITAGNGAFQPRRLELEGTAKYEKKNLHYFVDDMNKFAGKRVVVFGGGDSAVDWTMML 175 Query: 390 PPTAQ 394 P A+ Sbjct: 176 EPIAE 180 >3VEW-A nrPDB Length = 576 Score = 32.5 bits (72), Expect = 0.51, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 24/50 (48%), Gaps = 6/50 (12%) Query: 429 LLFEENNFKPFKYNDLGALAYLGSERAI------ATIRSGKRTFYTGGGL 472 + + P++Y DL A A ERA+ R+G+RT + GG+ Sbjct: 268 RVVRDTRRDPYEYRDLAATAQAALERAVFGLADSVLARTGERTLFVAGGV 317 >4C7Y-A nrPDB Length = 907 Score = 31.7 bits (70), Expect = 0.78, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 35/108 (32%), Gaps = 15/108 (13%) Query: 176 VGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVG 235 G EP F +P + D ++R + A LEKA ++ +SI V G Sbjct: 576 TGQEPEVFSLPDMID------------QLRPKYQAALEKAQKESTATHKKGVGISIGVYG 623 Query: 236 G---GPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNM 280 GP EA EL + + I V L Sbjct: 624 SGLDGPDASEAWAELNADGTITVHTAWEDHGQGADIGCVGTAHEALRP 671 >4GCM-A nrPDB Length = 312 Score = 31.7 bits (70), Expect = 0.81, Method: Composition-based stats. Identities = 43/262 (16%), Positives = 70/262 (26%), Gaps = 45/262 (17%) Query: 130 TSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLISAVGAEPNTFGIPGVT 189 T + + + + + E+ +I A GAE G+PG Sbjct: 66 TKMFEHAKKFGAVYQYGDIKSVEDKGEYKVINFGNKELTAKAVIIATGAEYKKIGVPGEQ 125 Query: 190 DYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVVGGGPTGVEAAGELQD 249 + G + + + +RL V+GGG + VE L Sbjct: 126 ELG----------------GRGVSYCAVCDGAFFKNKRLF---VIGGGDSAVEEGTFLTK 166 Query: 250 YVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKV 309 + + +I +N I + + Sbjct: 167 FADKVTIVHRRDELRAQRI-------------------LQDRAFKNDKIDFIWSHTLKSI 207 Query: 310 EEKQLLAK--TKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSKRGLAVN 367 EK T +EET + G K +T FK + N + + Sbjct: 208 NEKDGKVGSVTLTSTKDGSEETHEADGVFIYIGMKP---LTAPFKDLGITNDVGYIVTKD 264 Query: 368 DFLQVKGSNNIFAIGDNAFAGL 389 D IFA GD GL Sbjct: 265 D--MTTSVPGIFAAGDVRDKGL 284 >3EJX-A nrPDB Length = 317 Score = 31.4 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 32/126 (25%), Positives = 50/126 (39%), Gaps = 10/126 (7%) Query: 352 KKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQEAEYLAKNFDKMA 411 K P K+ V F++ G N F + DN + P Q Q A+ +NF A Sbjct: 12 KFSPASFLDKKETGVLHFVKYHGLGNDFILVDNRDSSEPKITQ--EQAAKLCDRNFGVGA 69 Query: 412 QIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDLGALAYLGSERAIATIRS--GKRTF--Y 467 F + D +F + +P + G + R IA + + GK +F + Sbjct: 70 DGVIFAMPGVNGTDYAMRIFNSDGSEP-EMCGNGVRCF---ARFIAELENLQGKHSFTIH 125 Query: 468 TGGGLM 473 TG GL+ Sbjct: 126 TGAGLI 131 >5GY2-A nrPDB Length = 455 Score = 31.4 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 32/82 (39%), Gaps = 11/82 (13%) Query: 368 DFLQVK--GSNNIFAIGDNAFAGLPPTAQVAHQEAEYLA---------KNFDKMAQIPNF 416 D L+V N+I A+GD +F GLP ++A + + + K+ N Sbjct: 347 DKLEVLDLSYNHIRALGDQSFLGLPNLKELALDTNQLKSVPDGIFDRLTSLQKIWLHTNP 406 Query: 417 QKNLSSRKDKIDLLFEENNFKP 438 R D + +N+ K Sbjct: 407 WDCSCPRIDYLSRWLNKNSQKE 428 >3D8X-A nrPDB Length = 326 Score = 31.4 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 60/338 (17%), Positives = 107/338 (31%), Gaps = 63/338 (18%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 V I+GSG A + I + + + + G + + I NF Sbjct: 12 KVTIIGSGPAAHT--AAIYLARAEI-----KPILYEGMMANGIAAG--GQLTTTTEIENF 62 Query: 115 ALKKKGN-----VTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKY 169 G + ++T + T T+ + S+ ++ AEP + Sbjct: 63 PGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFN-EDAEP--VTT 119 Query: 170 DYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 D +I A GA +PG Y ++ +A +P R + L Sbjct: 120 DAIILATGASAKRMHLPGEETY------------WQKGISACAVCDGAVPIF---RNKPL 164 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 V+GGG + E A L Y + I +K + Sbjct: 165 --AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIM-------------QKRAE-- 207 Query: 290 QSHLENTSIKVHLRT-AVAKVEEKQLL--AKTKHEDGKITEETIPYGTLIWATGNKARPV 346 +N I++ T A+ + +LL + K+ K E +P L +A G+ Sbjct: 208 ----KNEKIEILYNTVALEAKGDGKLLNALRIKN-TKKNEETDLPVSGLFYAIGHTPATK 262 Query: 347 ITDLFKKIPEQNSSKRG-LAVNDFLQVKGSNNIFAIGD 383 I + ++ + G + + FA GD Sbjct: 263 IV-----AGQVDTDEAGYIKTVPGSSLTSVPGFFAAGD 295 >2Q7V-A nrPDB Length = 325 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 48/332 (14%), Positives = 96/332 (28%), Gaps = 60/332 (18%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 +V+I+G G ++ I T + +S + + +P + E + NF Sbjct: 10 DVVIIGGGPAGLT--AAIYTGRAQLSTL------ILEKGMPGGQIAW------SEEVENF 55 Query: 115 ALKKK--GNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYL 172 + + + V + + V + + E + + Sbjct: 56 PGFPEPIAGMELAQRMHQQAEKFGAKVEMDEVQGVQHDATSHPYPFTVRGYNGEYRAKAV 115 Query: 173 ISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIV 232 I A GA+P GIPG ++ + + + ++ +V Sbjct: 116 ILATGADPRKLGIPGEDNF----------------WGKGVSTCATCDGFFYKGKK---VV 156 Query: 233 VVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSH 292 V+GGG VE L + + ++ Sbjct: 157 VIGGGDAAVEEGMFLTKFADEVTVIHRRDTLRANKVA-------------------QARA 197 Query: 293 LENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITE-ETIPYGTLIWATGNKARPVITDLF 351 N +K TAV +++ ++ K + K E + + G+ F Sbjct: 198 FANPKMKFIWDTAVEEIQGADSVSGVKLRNLKTGEVSELATDGVFIFIGHVPNTA----F 253 Query: 352 KKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 K + V D + +FA GD Sbjct: 254 VKDTVSLRDDGYVDVRDEIYT-NIPMLFAAGD 284 >4QI7-A nrPDB Length = 806 Score = 31.0 bits (68), Expect = 1.2, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 24/51 (47%), Gaps = 7/51 (13%) Query: 362 RGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVA-------HQEAEYLAK 405 V+ +V G++N++ + + F G+P T A H A+ LA+ Sbjct: 716 GTAVVDTNTRVYGTDNLYVVDASIFPGVPTTNPTAYIVVAAEHAAAKILAQ 766 >4NTC-A nrPDB Length = 335 Score = 31.0 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 50/346 (14%), Positives = 101/346 (29%), Gaps = 55/346 (15%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 +VLI+G+G +S + + + + Y +G N Sbjct: 16 DVLIIGAGPAGLSTATGLARQLHTAVVFDSGVYRNAKTQHMHNVLGWDH--------RNP 67 Query: 115 ALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLIS 174 A + ++I +T+ +QL++ ++ G H ++ + Sbjct: 68 AELRAAGRADLTTRYSTIQFQNSTIEAIRQVETNQLFEARDNEG-HSWYGRKV-----VL 121 Query: 175 AVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVVV 234 A G I G ++ +A + L E R ++ V+ Sbjct: 122 ATGVRDIPLDIEGYSE----------------CWANGIYHC--LFCDGYEERGQETVGVL 163 Query: 235 GGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHLE 294 GP A + L + + + ++L+ Q E Sbjct: 164 ALGPIANPARALHLARMALRLSE---------SVTIYTNGN-------EQLAKEIQQAAE 207 Query: 295 NTSIK---VHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLF 351 + + + + EK +AKT +E G L++ N V Sbjct: 208 ESPVGASGLKFEARPIRRFEKGDVAKTVIVHLGESESKTE-GFLVY---NPQTEVNGPFA 263 Query: 352 KKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAH 397 K++ + + +FA+GD A T V+ Sbjct: 264 KQLALNMTEGGDILTTPPFYETSVPGVFAVGDCATPLKAVTPAVSM 309 >5L3D-A nrPDB Length = 852 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 21/145 (14%), Positives = 52/145 (35%), Gaps = 14/145 (9%) Query: 36 GPTSFKTMKVIDPQHSDKP-NVLILGSGWGAISFLKHIDTKKYNVSIISPR--------- 85 G +F K I P + K V+I+GSG ++ + + + +V+++ R Sbjct: 260 GLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVAT 319 Query: 86 ----SYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTI 141 +Y + +G + + + K K YEA ++ +++ + Sbjct: 320 FRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVE 379 Query: 142 KSLSAVSQLYQPENHLGLHQAEPAE 166 + + + + +H + Sbjct: 380 QEFNRLLEATSYLSHQLDFNVLNNK 404 >3ABT-A nrPDB Length = 662 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 21/145 (14%), Positives = 52/145 (35%), Gaps = 14/145 (9%) Query: 36 GPTSFKTMKVIDPQHSDKP-NVLILGSGWGAISFLKHIDTKKYNVSIISPR--------- 85 G +F K I P + K V+I+GSG ++ + + + +V+++ R Sbjct: 89 GLINFGIYKRIKPLPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVAT 148 Query: 86 ----SYFLFTPLLPSAPVGTVDEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTI 141 +Y + +G + + + K K YEA ++ +++ + Sbjct: 149 FRKGNYVADLGAMVVTGLGGNPMAVVSKQVNMELAKIKQKCPLYEANGQAVPKEKDEMVE 208 Query: 142 KSLSAVSQLYQPENHLGLHQAEPAE 166 + + + + +H + Sbjct: 209 QEFNRLLEATSYLSHQLDFNVLNNK 233 >5MJK-A nrPDB Length = 327 Score = 31.0 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 38/212 (17%), Positives = 67/212 (31%), Gaps = 41/212 (19%) Query: 172 LISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSI 231 +I A GA IPG +YG + + F N E I Sbjct: 126 IIIATGANHRKLEIPGEEEYGA--RGVSYCAVCDGAFFRNQE-----------------I 166 Query: 232 VVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQS 291 +V+GGG + VE A L + +I I F+++ ++ Sbjct: 167 LVIGGGDSAVEEALYLTRFGQSVTIMHRRDKLRAQEI-------IQQRAFKEEKINFIWD 219 Query: 292 HLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLF 351 + + ++ ++K K+ E G I+ + ++DL Sbjct: 220 S-----VPMEIK----GDDKKIQSVVYKNVKTGEVTEKAFGGIFIYVGLDPVAEFVSDL- 269 Query: 352 KKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 + + G + D IFA+GD Sbjct: 270 -----GITDEAGWIITDDHMRTNIPGIFAVGD 296 >4CBQ-A nrPDB Length = 314 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 61/335 (18%), Positives = 105/335 (31%), Gaps = 54/335 (16%) Query: 51 SDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEP 110 S+ +V+I+GSG A + ++ S + P Y F A G + +IIE Sbjct: 2 SNIHDVVIIGSGPAAHTAAIYLGR-----SSLKPVMYEGFM-AGGVAAGGQLTTTTIIEN 55 Query: 111 IVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYD 170 F GN T T+ +++ V QP L E E+ Sbjct: 56 FPGFPNGIDGNELMMNMR-TQSEKYGTTIITETIDHVDFSTQPFK---LFTEEGKEVLTK 111 Query: 171 YLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLS 230 +I A GA +PG Y + + + P R + Sbjct: 112 SVIIATGATAKRMHVPGEDKY----------------WQNGVSACAICDGAVPIFRNKV- 154 Query: 231 IVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQ 290 ++VVGGG +E A L Y + + K + Sbjct: 155 LMVVGGGDAAMEEALHLTKYGSKVIILHRRDAFRA----------------SKTMQERVL 198 Query: 291 SHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEE--TIPYGTLIWATGNKARPVIT 348 +H + I+V + + ++E L ++ E +P L +A G+ Sbjct: 199 NHPK---IEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAGLFYAIGHSPNSK-- 253 Query: 349 DLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 F + + + + +FA GD Sbjct: 254 --FLGGQVKTADDGYILTEG--PKTSVDGVFACGD 284 >6GAR-A nrPDB Length = 349 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 43/235 (18%), Positives = 83/235 (35%), Gaps = 22/235 (9%) Query: 224 ERRRLLSIVVVGGGPTGVEAA-----GELQDYVHQDLRKFLPALAEEVQIHLVEALPIVL 278 R L + V+GGGP G+ +A E++ + + + + + + ++ Sbjct: 2 NREELFDVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPHLGGKIHVYPEKMIWDVGGLLP 61 Query: 279 NMFEKKLSSYAQSHLENTSIKVHLRTAVAKV---EEKQLLAKTKHEDGKITEETIPYGTL 335 +K + Q L +V L T V + ++ KT + ++ T+ Sbjct: 62 VTGDKLIEQLVQQGLTFKP-EVVLDTKVESIIRNQDGTFTLKTSTGEEHFSK------TV 114 Query: 336 IWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDNAFAG----LPP 391 I ATG+ + S V + KG I + G N+ L P Sbjct: 115 IVATGSGILKPQKLSIEGAERFEVSNLNYTVKSLKRFKGKTVIISGGGNSAVDWANELEP 174 Query: 392 TAQVAHQ--EAEYLAKNFDKMAQIPNFQKNLSSRKDKIDLLFEENNFKPFKYNDL 444 A+ + E L+ + ++ Q+ N I L +N + +Y +L Sbjct: 175 IAKKVYVTYRKEELSGHEAQVKQLMNSSAE-CFFNTSITKLIAGDNHEAIEYVEL 228 >4ZN0-A nrPDB Length = 311 Score = 29.8 bits (65), Expect = 2.6, Method: Composition-based stats. Identities = 55/333 (16%), Positives = 106/333 (31%), Gaps = 63/333 (18%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNV-SIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVN 113 +++I+G G ++ I +Y + ++I R+ G + I+E Sbjct: 9 DLIIIGGGPAGLT--AGIYAVRYGLDTLILERNEI----------SGQISMADIVENYPG 56 Query: 114 FALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLI 173 F +++ E V +K+ + E + + +++ +I Sbjct: 57 FP-----SISGLEL-MERFRTHAQEVGVKTTITEVLSVRSEGTKKIITTDSGDLEAKAVI 110 Query: 174 SAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVV 233 A GA P G+PG + + + D R + V Sbjct: 111 IATGANPKHLGVPGEKE-------------------LISKGVSYCAICDGPFFRNKIVAV 151 Query: 234 VGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHL--VEALPIVLNMFEKKLSSYAQS 291 VGGG + V A L + + ++ V+ P + E L+S+ Sbjct: 152 VGGGNSAVTDALFLSKVAQKVYLVHRRDHLKAARVLQDRVDGTPNI----ELILNSHVLE 207 Query: 292 HLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLF 351 V R + KVE+ + + + T E G I+ G D+ Sbjct: 208 -------IVGTREGIKKVEK----IILEDVNSRETRELSTNGVFIY-VGIHPNTEFVDVE 255 Query: 352 KKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGDN 384 K + R + ++ I+A GD Sbjct: 256 KDEGGFIKTDRWMETSEK-------GIYAAGDC 281 >4QI6-A nrPDB Length = 807 Score = 29.8 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Query: 353 KIPEQNSSKRGLAVND-FLQVKGSNNIFAIGDNAFAGLPPTAQVA--HQEAEYLAKNFDK 409 K+ + K G AV D +V G++N+F I + F G+P T + AE+ + Sbjct: 707 KLGTDDGRKGGSAVVDLDTRVYGTDNLFVIDASIFPGVPTTNPTSYIVVAAEHASSRILA 766 Query: 410 MAQIPNFQK 418 + + K Sbjct: 767 LPDLEPVPK 775 >4QI5-A nrPDB Length = 585 Score = 29.8 bits (65), Expect = 2.8, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 31/69 (44%), Gaps = 3/69 (4%) Query: 353 KIPEQNSSKRGLAVND-FLQVKGSNNIFAIGDNAFAGLPPTAQVA--HQEAEYLAKNFDK 409 K+ + K G AV D +V G++N+F I + F G+P T + AE+ + Sbjct: 485 KLGTDDGRKGGSAVVDLDTRVYGTDNLFVIDASIFPGVPTTNPTSYIVVAAEHASSRILA 544 Query: 410 MAQIPNFQK 418 + + K Sbjct: 545 LPDLEPVPK 553 >5XK2-A nrPDB Length = 286 Score = 29.4 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 50/140 (35%), Gaps = 18/140 (12%) Query: 41 KTMKVIDPQHSDKPNVLILGSGWG---AISFLKHIDTKKYNVSIISPRSYFLFTPLLPSA 97 KT+ + P+HSD ++++G G A + TK Y+ + Y P + + Sbjct: 133 KTLDELKPEHSDY-KIVVVGHSLGAAIASLAAADLRTKNYDAIL-----YAYAAPRVANK 186 Query: 98 PVGTV--------DEKSIIEPIVNFALKKKGNVTYYEAEATSINPDRNTVTIKSLSAVSQ 149 P+ +P+ L G V + E PD TVT ++ + Sbjct: 187 PLAEFITNQGNNYRFTHNDDPVPKLPLLTMGYV-HISPEYYITAPDNTTVTDNQVTVLDG 245 Query: 150 LYQPENHLGLHQAEPAEIKY 169 + + G P + + Sbjct: 246 YVNFKGNTGTSGGLPDLLAF 265 >3LZX-A nrPDB Length = 332 Score = 29.4 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 43/215 (20%), Positives = 79/215 (36%), Gaps = 22/215 (10%) Query: 224 ERRRLLSIVVVGGGPTGV---------EAAGELQDYVHQDLRKFLPALAEEVQIHLVEAL 274 E ++ I ++GGGP G+ +A+ ++ + + Q + L AL E I+ V Sbjct: 3 EDTKVYDITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQ-LSALYPEKYIYDVAGF 61 Query: 275 PIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYG- 333 P + ++L + + + + L AV VE+ + +T E Y Sbjct: 62 PKIR---AQELINNLKEQMAKFDQTICLEQAVESVEK-----QADGVFKLVTNEETHYSK 113 Query: 334 TLIWATGNKARPVITDLFKKIPEQNSSKRGLAVNDFLQVKGSN-NIFAIGDNAFAGLPPT 392 T+I GN A + + V+D + G I GD+A Sbjct: 114 TVIITAGNGAFKPRKLELENAEQYEGKNLHYFVDDLQKFAGRRVAILGGGDSAVDWALML 173 Query: 393 AQVAHQEAEYLAKNFDKMAQIPNFQKNLSSRKDKI 427 +A + + DK + +NL + K + Sbjct: 174 EPIAKEV--SIIHRRDKFRAHEHSVENLHASKVNV 206 >1QO8-A nrPDB Length = 566 Score = 29.4 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 10/47 (21%), Positives = 18/47 (38%) Query: 41 KTMKVIDPQHSDKPNVLILGSGWGAISFLKHIDTKKYNVSIISPRSY 87 K K I S+ VL++G+G + NV ++ + Sbjct: 109 KIQKAIAAGPSETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAPF 155 >3DV8-A nrPDB Length = 220 Score = 29.0 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 26/166 (15%), Positives = 52/166 (31%), Gaps = 16/166 (9%) Query: 309 VEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPVITDLFKKIPEQNSSK------- 361 + + + K G L+ +G +++D ++I Sbjct: 22 ISDNLITQHVKKGTIIHNGNMDCTGLLLVKSGQLRTYILSDEGREITLYRLFDMDMCLLS 81 Query: 362 -----RGLAVNDFLQVKGSNNIFAIGDNAFAG-LPPTAQVAHQEAEYLAKNFDKMAQIPN 415 R + ++ + +++ I + G + +A VA+ E +A F + + Sbjct: 82 ASCIMRSIQFEVTIEAEKDTDLWIIPAEIYKGIMKDSAPVANYTNELMATRFSDVMWLIE 141 Query: 416 FQKNLSSRKDKIDLLFEE---NNFKPFKYNDLGALAYLGSERAIAT 458 S K L EE K +LGS R + T Sbjct: 142 QIMWKSLDKRVASFLLEETSIEGTNELKITHETIANHLGSHREVIT 187 >4Y4M-A nrPDB Length = 290 Score = 28.7 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 27/183 (14%), Positives = 55/183 (30%), Gaps = 22/183 (12%) Query: 231 IVVVGGGPTGVEAAGELQ---------DYVHQDLRKFLPALAEEVQIHLVEALPIVLNMF 281 +V+VG GP+G+ A L + I + E +L Sbjct: 62 VVIVGAGPSGLTCARYLAKEGFKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADELLREV 121 Query: 282 EKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGN 341 KL + S++V + AVA ++ KI + ++ G Sbjct: 122 GIKLIDMGDGYYVADSVEVPAKLAVAAMDAGA----------KILTGIVVEDLILREDGV 171 Query: 342 KARPVITDLFKKIPEQNSS---KRGLAVNDFLQVKGSNNIFAIGDNAFAGLPPTAQVAHQ 398 + + ++ + + V+ NI + A +P + + Sbjct: 172 AGVVINSYAIERAGLHIDPLTIRSKVVVDATGHEASIVNILVKKNKLEADVPGEKSMWAE 231 Query: 399 EAE 401 + E Sbjct: 232 KGE 234 >6BPY-A nrPDB Length = 374 Score = 28.7 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 51/337 (15%), Positives = 96/337 (28%), Gaps = 55/337 (16%) Query: 55 NVLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNF 114 V+I+GSG A + ++ + + L G + + I NF Sbjct: 6 KVVIIGSGPAAHTAAIYLSRAEL-------KPVLYEGMLANGTAAG--GQLTTTTDIENF 56 Query: 115 ALKKKG-----NVTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKY 169 G + ++ + T TI + S+ ++ + Sbjct: 57 PGFPDGIGGAELMENMRKQSIRFGTEVITETISRVDLSSKPFKLWTEWNDGPDKEPACTA 116 Query: 170 DYLISAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLL 229 D +I A GA +PG Y + + + P R Sbjct: 117 DAVIIATGANARRLNLPGEETY----------------WQNGISACAVCDGAVPIFRN-K 159 Query: 230 SIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYA 289 + V+GGG + E A FL V + + K+L ++ Sbjct: 160 PLYVIGGGDSAAEEA------------MFLAKYGSSVTVLVRRDKLRASKAMAKRLLAHP 207 Query: 290 QSHLENTSIKVHLRTAVAKVEE-KQL--LAKTKHEDGKITEETIPYGTLIWATGNKARPV 346 + + ++ T V ++ L + K+ EE + L +A G+ Sbjct: 208 KVTVRFNTV----ATEVLGEKKPNGLMTHLRIKNTVTGE-EEIVDANGLFYAVGHDPATA 262 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 + K + +FA GD Sbjct: 263 LV----KGQIDLDEDGYIITKPGTSYTSREGVFACGD 295 >5ZYN-B nrPDB Length = 471 Score = 28.7 bits (62), Expect = 6.5, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 32/66 (48%), Gaps = 8/66 (12%) Query: 275 PIVLNMFEKKLSSYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGT 334 P+++N F+K +S+ + ++ + VH K+ EK + K K +E + G Sbjct: 379 PLIINAFDKDISTESTVYVGEVTPVVHFTMGGVKINEKSQVIK------KNSESVLSNG- 431 Query: 335 LIWATG 340 I+A G Sbjct: 432 -IFAAG 436 >1VDC-A nrPDB Length = 333 Score = 28.3 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 25/157 (15%), Positives = 45/157 (28%), Gaps = 19/157 (12%) Query: 227 RLLSIVVVGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLS 286 R + V+GGG + +E A L Y + +I AL + + Sbjct: 158 RNKPLAVIGGGDSAMEEANFLTKYGSKVYIIHRRDAFRASKIMQQRALSN--PKIDVIWN 215 Query: 287 SYAQSHLENTSIKVHLRTAVAKVEEKQLLAKTKHEDGKITEETIPYGTLIWATGNKARPV 346 S + V + + + D K++ L +A G++ Sbjct: 216 SSVVEAYGDG------ERDVLGGLKVKNVVTGDVSDLKVSG-------LFFAIGHEPATK 262 Query: 347 ITDLFKKIPEQNSSKRGLAVNDFLQVKGSNNIFAIGD 383 D + S + +FA GD Sbjct: 263 FLD----GGVELDSDGYVVTKPGTTQTSVPGVFAAGD 295 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.119 0.294 Lambda K H 0.267 0.0367 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 16,282,497 Number of Sequences: 36641 Number of extensions: 624790 Number of successful extensions: 2521 Number of sequences better than 10.0: 129 Number of HSP's better than 10.0 without gapping: 56 Number of HSP's successfully gapped in prelim test: 137 Number of HSP's that attempted gapping in prelim test: 2202 Number of HSP's gapped (non-prelim): 260 length of query: 513 length of database: 10,336,785 effective HSP length: 101 effective length of query: 412 effective length of database: 6,636,044 effective search space: 2734050128 effective search space used: 2734050128 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.3 bits)