BLASTP 2.2.23 [Feb-03-2010]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.


Reference for compositional score matrix adjustment: Altschul, Stephen F., 
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.


Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,  
Eugene V. Koonin, and Stephen F. Altschul (2001), 
"Improving the accuracy of PSI-BLAST protein database searches with 
composition-based statistics and other refinements",  Nucleic Acids Res. 29:2994-3005.

Query= P31324
         (416 letters)

Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 
           36,641 sequences; 10,336,785 total letters

Searching..................................................done


Results from round 1


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

4X6Q-B nrPDB                                                          858   0.0  
1CX4-A nrPDB                                                          625   e-179
3J4Q-B nrPDB                                                          559   e-160
2QVS-B nrPDB                                                          492   e-139
4DIN-B nrPDB                                                          249   1e-66
6BYS-B nrPDB                                                          235   3e-62
2QCS-B nrPDB                                                          230   7e-61
5KBF-A nrPDB                                                          197   8e-51
5J3U-A nrPDB                                                          174   6e-44
4Z07-A nrPDB                                                          125   4e-29
5FET-A nrPDB                                                          122   4e-28
3SHR-A nrPDB                                                          121   5e-28
5DYK-A nrPDB                                                          117   8e-27
6FTF-B nrPDB                                                          105   3e-23
6BQ8-A nrPDB                                                           71   1e-12
5H78-A nrPDB                                                           68   8e-12
4QX5-A nrPDB                                                           66   3e-11
5JAX-A nrPDB                                                           66   4e-11
5H77-A nrPDB                                                           65   6e-11
5XBY-A nrPDB                                                           63   3e-10
5V4S-A nrPDB                                                           51   8e-07
6CJQ-A nrPDB                                                           49   5e-06
4MGY-E nrPDB                                                           46   3e-05
1O7F-A nrPDB                                                           45   5e-05
4EV0-A nrPDB                                                           45   6e-05
4F7Z-A nrPDB                                                           45   7e-05
4AVC-A nrPDB                                                           44   1e-04
3DKW-A nrPDB                                                           42   4e-04
4CHV-A nrPDB                                                           42   4e-04
5JON-A nrPDB                                                           41   0.001
3I59-A nrPDB                                                           39   0.003
5W5B-A nrPDB                                                           39   0.004
4ORF-A nrPDB                                                           39   0.004
5U6P-A nrPDB                                                           39   0.004
4CYD-A nrPDB                                                           37   0.022
2GAU-A nrPDB                                                           36   0.039
3H3Z-A nrPDB                                                           33   0.24 
4I0B-A nrPDB                                                           32   0.56 
3KCC-A nrPDB                                                           32   0.63 
5H3O-A nrPDB                                                           30   2.0  
5I62-A nrPDB                                                           29   3.1  
1DK5-A nrPDB                                                           29   3.9  

>4X6Q-B nrPDB
          Length = 416

 Score =  858 bits (2218), Expect = 0.0,   Method: Compositional matrix adjust.
 Identities = 415/416 (99%), Positives = 416/416 (100%)

Query: 1   MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
           MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD
Sbjct: 1   MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60

Query: 61  AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120
           AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP
Sbjct: 61  AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120

Query: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180
           DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI
Sbjct: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180

Query: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPG 240
           DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP+AATITATSPG
Sbjct: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPKAATITATSPG 240

Query: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300
           ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ
Sbjct: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300

Query: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360
           IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA
Sbjct: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360

Query: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416
           ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Sbjct: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416


>1CX4-A nrPDB
          Length = 305

 Score =  625 bits (1611), Expect = e-179,   Method: Compositional matrix adjust.
 Identities = 300/305 (98%), Positives = 303/305 (99%)

Query: 112 SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 171
           SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK
Sbjct: 1   SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 60

Query: 172 LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 231
           LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA
Sbjct: 61  LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 120

Query: 232 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 291
           ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG
Sbjct: 121 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 180

Query: 292 TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
           TKVYNDGEQIIAQGD ADSFFIVESGEV+ITMKRKGKS++EENGAVEIARC RGQYFGEL
Sbjct: 181 TKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGEL 240

Query: 352 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 411
           ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI
Sbjct: 241 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 300

Query: 412 VEPTA 416
           VEPTA
Sbjct: 301 VEPTA 305


>3J4Q-B nrPDB
          Length = 402

 Score =  559 bits (1441), Expect = e-160,   Method: Compositional matrix adjust.
 Identities = 276/415 (66%), Positives = 329/415 (79%), Gaps = 21/415 (5%)

Query: 3   IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAG 62
           I+IPAGLTELLQG+TVEVLR QP DL++FA+++FTRL+ E  R+ +  F     T+    
Sbjct: 4   IQIPAGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLR-EARRQESDTFIVSPTTFHTQE 62

Query: 63  AAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDE 122
           ++A   I                E+GE +  +E      PV ++FTRR SVCAE +NPDE
Sbjct: 63  SSAVPVI---------------EEDGESDSDSEDADLEVPVPSKFTRRVSVCAETFNPDE 107

Query: 123 EEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQ 182
           EE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDAMFEK+VK  EHVIDQ
Sbjct: 108 EEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQ 167

Query: 183 GDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGAL 242
           GDDGDNFYVI+RGT+DI V  D   R VG YDNRGSFGELALMYNTPRAATI ATS G+L
Sbjct: 168 GDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSEGSL 227

Query: 243 WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQII 302
           WGLDRVTFRRIIVKNNAKKRKM+ESFIES+P  KSLE+SER+K+VDVIG K+Y DGE+II
Sbjct: 228 WGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERII 287

Query: 303 AQGDLADSFFIVESGEVKITMKRKGKSEVEENGA---VEIARCFRGQYFGELALVTNKPR 359
           AQG+ ADSF+I+ESGEV I ++ K KS   +NG    VEIA C +GQYFGELALVTNKPR
Sbjct: 288 AQGEKADSFYIIESGEVSILIRSKTKS--NKNGGNQEVEIAHCHKGQYFGELALVTNKPR 345

Query: 360 AASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEP 414
           AASA+A+G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +FG+N+D+++P
Sbjct: 346 AASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLMDP 400


>2QVS-B nrPDB
          Length = 310

 Score =  492 bits (1267), Expect = e-139,   Method: Compositional matrix adjust.
 Identities = 234/310 (75%), Positives = 269/310 (86%), Gaps = 5/310 (1%)

Query: 108 TRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDA 167
           TRR SVCAE +NPDEEE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDA
Sbjct: 1   TRRVSVCAETFNPDEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDA 60

Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYN 227
           MFEK+VK  EHVIDQGDDGDNFYVI+RGT+DI V  D   R VG YDNRGSFGELALMYN
Sbjct: 61  MFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYN 120

Query: 228 TPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVV 287
           TPRAATI ATS G+LWGLDRVTFRRIIVKNNAKKRKM+ESFIES+P  KSLE+SER+K+V
Sbjct: 121 TPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIV 180

Query: 288 DVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGA---VEIARCFR 344
           DVIG K+Y DGE+IIAQG+ ADSF+I+ESGEV I ++ K KS   +NG    VEIA C +
Sbjct: 181 DVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKS--NKNGGNQEVEIAHCHK 238

Query: 345 GQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVAL 404
           GQYFGELALVTNKPRAASA+ +G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +
Sbjct: 239 GQYFGELALVTNKPRAASAYGVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKM 298

Query: 405 FGTNMDIVEP 414
           FG+N+D+++P
Sbjct: 299 FGSNLDLMDP 308


>4DIN-B nrPDB
          Length = 381

 Score =  249 bits (637), Expect = 1e-66,   Method: Compositional matrix adjust.
 Identities = 147/392 (37%), Positives = 210/392 (53%), Gaps = 46/392 (11%)

Query: 8   GLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGG 67
           G+ ++L+   V +   +P   ++F  +HF +L++E  R+  AR                 
Sbjct: 26  GIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILAR----------------- 68

Query: 68  GIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA 127
                         +S+S++   +E       N PV+    RR  V AE Y     E+DA
Sbjct: 69  -------------QKSNSQSDSHDEEVSPTPPN-PVVKARRRRGGVSAEVYT----EEDA 110

Query: 128 ES--RIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDD 185
            S  R + PK       L +A    +LF +LD  + S + DAMF      GE VI QG++
Sbjct: 111 VSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNE 170

Query: 186 GDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGL 245
           GDNFYV+D+G  D+YV     G  V N    GSFGELAL+Y TPRAAT+ A +   LWG+
Sbjct: 171 GDNFYVVDQGEVDVYVN----GEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGI 226

Query: 246 DRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQG 305
           DR ++RRI++ +  +KRKMYE F+  +  L+SLE  ERL V D +    + DGE+I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQG 286

Query: 306 DLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA 365
           +  D F+I+  G   +  +R    E      VE+ R     YFGE+AL+ N+PRAA+  A
Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEY-----VEVGRLGPSDYFGEIALLLNRPRAATVVA 341

Query: 366 IGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
            G +KC+ +D   FER+LGPC EI+KRNI  Y
Sbjct: 342 RGPLKCVKLDRPRFERVLGPCSEILKRNIQRY 373


>6BYS-B nrPDB
          Length = 379

 Score =  235 bits (599), Expect = 3e-62,   Method: Compositional matrix adjust.
 Identities = 132/298 (44%), Positives = 181/298 (60%), Gaps = 15/298 (5%)

Query: 102 PVINRFTRRASVCAEAYNPDEEEDDAES--RIIHPKTDDQRNRLQEACKDILLFKNLDPE 159
           PV+    RR ++ AE Y     E+DA S  R + PK       L +A +  +LF +LD  
Sbjct: 87  PVVKGRRRRGAISAEVYT----EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDN 142

Query: 160 QMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSF 219
           + S + DAMF      GE VI QGD+GDNFYVID+G  D+YV  +     VG     GSF
Sbjct: 143 ERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEW-ATSVGE---GGSF 198

Query: 220 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLE 279
           GELAL+Y TPRAAT+ A +   LWG+DR ++RRI++ +  +KRKMYE F+  +  L+SL+
Sbjct: 199 GELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD 258

Query: 280 VSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEI 339
             ERL V D +    + DG++I+ QG+  D FFI+  G   +  +R   SE EE   VE+
Sbjct: 259 KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRR---SENEE--FVEV 313

Query: 340 ARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
            R     YFGE+AL+ N+PRAA+  A G +KC+ +D   FER+LGPC +I+KRNI  Y
Sbjct: 314 GRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 371


>2QCS-B nrPDB
          Length = 291

 Score =  230 bits (587), Expect = 7e-61,   Method: Compositional matrix adjust.
 Identities = 127/289 (43%), Positives = 177/289 (61%), Gaps = 11/289 (3%)

Query: 109 RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAM 168
           RR ++ AE Y   EE+  +  R + PK       L +A +  +LF +LD  + S + DAM
Sbjct: 5   RRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAM 62

Query: 169 FEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNT 228
           F      GE VI QGD+GDNFYVID+G  D+YV  +     VG     GSFGELAL+Y T
Sbjct: 63  FPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEW-ATSVGE---GGSFGELALIYGT 118

Query: 229 PRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVD 288
           PRAAT+ A +   LWG+DR ++RRI++ +  +KRKMYE F+  +  L+SL+  ERL V D
Sbjct: 119 PRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVAD 178

Query: 289 VIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYF 348
            +    + DG++I+ QG+  D FFI+  G   +  +R   SE EE   VE+ R     YF
Sbjct: 179 ALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRR---SENEE--FVEVGRLGPSDYF 233

Query: 349 GELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
           GE+AL+ N+P+AA+  A G +KC+ +D   FER+LGPC +I+KRNI  Y
Sbjct: 234 GEIALLMNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 282


>5KBF-A nrPDB
          Length = 301

 Score =  197 bits (501), Expect = 8e-51,   Method: Compositional matrix adjust.
 Identities = 113/297 (38%), Positives = 174/297 (58%), Gaps = 12/297 (4%)

Query: 109 RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAM 168
           +R SV AEAY    ++ D     ++ K + ++ +++EA  +  LF +L+ ++   +++A 
Sbjct: 6   KRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIVNAF 65

Query: 169 FEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELALMYN 227
           F+K V++G ++I++GD GD  YVID+G  +IY  K +     +    ++  FGELAL+YN
Sbjct: 66  FDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALLYN 125

Query: 228 TPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVV 287
           + RAAT TA +   LW LDR +F  II    AKKRKMYE  +  +  LK ++  ER KV 
Sbjct: 126 SKRAATATALTKCHLWALDRESFTYIIKDMVAKKRKMYEDILSHVNILKDMDPYERCKVA 185

Query: 288 DVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQY 347
           D + +K YNDGE II +G+  D+FFI+  G    +   K            I    +G Y
Sbjct: 186 DCLKSKSYNDGEIIIKEGEEGDTFFILIDGNAVASKDNKV-----------IKTYTKGDY 234

Query: 348 FGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVAL 404
           FGELAL+ NKPRAA+  A    + + +D ++F+RLLGP  +I+ RN+  Y++ L  L
Sbjct: 235 FGELALLKNKPRAATIKAQNFCQVVYLDRKSFKRLLGPIEDILHRNVENYKKVLNEL 291


>5J3U-A nrPDB
          Length = 261

 Score =  174 bits (441), Expect = 6e-44,   Method: Compositional matrix adjust.
 Identities = 95/266 (35%), Positives = 151/266 (56%), Gaps = 5/266 (1%)

Query: 132 IHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYV 191
           ++ K + Q+ +L+   +   LF +LD + ++ V+ AM EK ++    +I +GDDG+  Y+
Sbjct: 1   VYEKDEGQKEQLERILRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYI 60

Query: 192 IDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
           +  G  +     DG  R V       +FGELAL+YN PRAAT+T+ S   LW L R TF 
Sbjct: 61  VQSGELNCSKLIDGEERVVKVVGPGDAFGELALLYNAPRAATVTSVSACDLWELGRDTFN 120

Query: 252 RIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSF 311
            I+     K+R MY+SF++S+  L  ++  ER KV D + T+++ DG  I+ QG+L D F
Sbjct: 121 AIVKDAATKRRSMYDSFLKSVHILDGMDAYERGKVADALRTEMFTDGAYIVRQGELGDVF 180

Query: 312 FIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKC 371
           +IVE G    T     KS       +E+ +   G YFGELAL+  +PRAA+  A G  K 
Sbjct: 181 YIVEEGSAVAT-----KSFGPGQPPIEVKKYQAGDYFGELALINEEPRAANVIAHGICKV 235

Query: 372 LAMDVQAFERLLGPCMEIMKRNIATY 397
             ++ ++F+RL+G   +++ +  + Y
Sbjct: 236 ACLERKSFKRLMGSVQDLLSKKASEY 261



 Score = 58.5 bits (140), Expect = 5e-09,   Method: Compositional matrix adjust.
 Identities = 44/160 (27%), Positives = 79/160 (49%), Gaps = 11/160 (6%)

Query: 99  FNAPVINRFTRRASVCA-EAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLD 157
           +NAP      R A+V +  A +  E   D  + I+      +R+      K + +   +D
Sbjct: 95  YNAP------RAATVTSVSACDLWELGRDTFNAIVKDAATKRRSMYDSFLKSVHILDGMD 148

Query: 158 PEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRC---VGNYD 214
             +  +V DA+  ++  +G +++ QG+ GD FY+++ G+  +  K  G G+    V  Y 
Sbjct: 149 AYERGKVADALRTEMFTDGAYIVRQGELGDVFYIVEEGS-AVATKSFGPGQPPIEVKKYQ 207

Query: 215 NRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
               FGELAL+   PRAA + A     +  L+R +F+R++
Sbjct: 208 AGDYFGELALINEEPRAANVIAHGICKVACLERKSFKRLM 247


>4Z07-A nrPDB
          Length = 262

 Score =  125 bits (314), Expect = 4e-29,   Method: Compositional matrix adjust.
 Identities = 79/252 (31%), Positives = 126/252 (50%), Gaps = 9/252 (3%)

Query: 133 HPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVI 192
           +PK+   ++ ++EA  D    KNL+  Q+ +++D M+     +   +I +GD G   YV+
Sbjct: 10  YPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 69

Query: 193 DRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
           + G  +  V  +GV  C         FGELA++YN  R AT+       LW +DR  F+ 
Sbjct: 70  EDGKVE--VTKEGVKLCTMGPGK--VFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 125

Query: 253 IIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFF 312
           I+++    K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FF
Sbjct: 126 IMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFF 185

Query: 313 IVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCL 372
           I+  G V +T     + +      V +    +G +FGE AL     R A+  A   V CL
Sbjct: 186 IISKGTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCL 240

Query: 373 AMDVQAFERLLG 384
            +D  +F+ L+G
Sbjct: 241 VIDRDSFKHLIG 252


>5FET-A nrPDB
          Length = 847

 Score =  122 bits (305), Expect = 4e-28,   Method: Compositional matrix adjust.
 Identities = 78/263 (29%), Positives = 135/263 (51%), Gaps = 15/263 (5%)

Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
           ++ + K+ L+   L+  ++  + + M   + K G+ VI QG+ G  F++I+ G FD+YV 
Sbjct: 43  IKASLKNNLVCSTLNDNEILTLSNYMQFFVFKGGDLVIKQGEKGSYFFIINSGKFDVYVN 102

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKR 262
                + V +     SFGE AL++NT R+ATI A + G LWG+ R TFR  + + + +  
Sbjct: 103 ----DKKVKSMGKGSSFGEAALIHNTQRSATIMAETDGTLWGVQRSTFRATLKQLSNRNF 158

Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
               SFI+S+     L  +++  + +    +++  GE I+ QGD  D  FI++ G+  + 
Sbjct: 159 NENRSFIDSVSVFDMLTEAQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKEGKATVF 218

Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERL 382
           +  K           EI    +G YFGE AL+ ++PR+A+  A     C ++  +    +
Sbjct: 219 INDK-----------EIRVLNKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIV 267

Query: 383 LGPCMEIMKRNIATYEEQLVALF 405
           LG    ++ RNI T   Q   +F
Sbjct: 268 LGNLQVVLFRNIMTEALQQSEIF 290



 Score = 56.6 bits (135), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 5/116 (4%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI 199
            N  +   K + +F+ L  +Q + +++A      +EG+++I +G+ G  FY+I  G  ++
Sbjct: 400 HNNKKSIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEV 459

Query: 200 YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA-LWGLDRVTFRRII 254
             K     R +G  D    FGE AL+Y+ PR A+I + +     W +D+  F +II
Sbjct: 460 -TKNGKRLRTLGKND---YFGERALLYDEPRTASIISKATSVECWFVDKSVFLQII 511



 Score = 55.8 bits (133), Expect = 3e-08,   Method: Compositional matrix adjust.
 Identities = 55/266 (20%), Positives = 118/266 (44%), Gaps = 30/266 (11%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGD-DGDNFYVIDRGTFD 198
           RN + EA +   +F+    EQ++ + D    +      H++ +       + ++  G  +
Sbjct: 277 RNIMTEALQQSEIFRQFSAEQLNDLADTAIVRDYPANYHILHKDKVKSVKYLIVLEGKVE 336

Query: 199 IYVKCDGVG-----RCVGN---YDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTF 250
           +++  + +G     +  G+    + +  F       +  + A IT +      G + +  
Sbjct: 337 LFLDDESIGILTRGKSFGDQYVLNQKQKFRHTVKSLDVCKIALITESCLADCLGDNNIDA 396

Query: 251 RRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADS 310
               + +N KK     S I+ +   + L   +   +++   T  Y +G+ II +G++   
Sbjct: 397 S---IDHNNKK-----SIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSR 448

Query: 311 FFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-V 369
           F+I+++GEV++T   K    + +N            YFGE AL+ ++PR AS  +  T V
Sbjct: 449 FYIIKNGEVEVTKNGKRLRTLGKN-----------DYFGERALLYDEPRTASIISKATSV 497

Query: 370 KCLAMDVQAFERLL-GPCMEIMKRNI 394
           +C  +D   F +++ GP +  ++  I
Sbjct: 498 ECWFVDKSVFLQIIQGPMLTHLEERI 523


>3SHR-A nrPDB
          Length = 299

 Score =  121 bits (304), Expect = 5e-28,   Method: Compositional matrix adjust.
 Identities = 78/250 (31%), Positives = 126/250 (50%), Gaps = 9/250 (3%)

Query: 135 KTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDR 194
           K++  ++ ++EA  D    KNL+  Q+ +++D M+     +   +I +GD G   YV++ 
Sbjct: 29  KSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMED 88

Query: 195 GTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
           G  +  V  +GV  C         FGELA++YN  R AT+       LW +DR  F+ I+
Sbjct: 89  GKVE--VTKEGVKLCTMGPGK--VFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 144

Query: 255 VKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIV 314
           ++    K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FFI+
Sbjct: 145 MRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFII 204

Query: 315 ESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAM 374
             G+V +T     + +      V +    +G +FGE AL     R A+  A   V CL +
Sbjct: 205 SKGKVNVT-----REDSPNEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVI 259

Query: 375 DVQAFERLLG 384
           D  +F+ L+G
Sbjct: 260 DRDSFKHLIG 269



 Score = 47.0 bits (110), Expect = 2e-05,   Method: Compositional matrix adjust.
 Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 10/134 (7%)

Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
           +     E  K +  F++L  E +S++ D + E   + GE++I QG  GD F++I +G  +
Sbjct: 151 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVN 210

Query: 199 IYVKCDGVG------RCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
           +  + D         R +G  D    FGE AL     R A + A        +DR +F+ 
Sbjct: 211 V-TREDSPNEDPVFLRTLGKGD---WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKH 266

Query: 253 IIVKNNAKKRKMYE 266
           +I   +    K YE
Sbjct: 267 LIGGLDDVSNKAYE 280


>5DYK-A nrPDB
          Length = 853

 Score =  117 bits (293), Expect = 8e-27,   Method: Compositional matrix adjust.
 Identities = 80/282 (28%), Positives = 139/282 (49%), Gaps = 18/282 (6%)

Query: 124 EDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQG 183
           ED  E R    K  +  + ++ + K+ L+   L+  ++  + + M   + K G  VI QG
Sbjct: 33  EDHLELR---EKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNYMQFFVFKSGNLVIKQG 89

Query: 184 DDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALW 243
           + G  F++I+ G FD+YV      + V       SFGE AL++NT R+ATI A + G LW
Sbjct: 90  EKGSYFFIINSGKFDVYVN----DKKVKTMGKGSSFGEAALIHNTQRSATIIAETDGTLW 145

Query: 244 GLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIA 303
           G+ R TFR  + + + +      +FI+S+     L  +++  + +    + +  GE I+ 
Sbjct: 146 GVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVK 205

Query: 304 QGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA 363
           QGD  D  +I++ G+  + +  +           EI    +G YFGE AL+ ++PR+A+ 
Sbjct: 206 QGDYGDVLYILKEGKATVYINDE-----------EIRVLEKGSYFGERALLYDEPRSATI 254

Query: 364 HAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALF 405
            A     C ++  +    +LG    ++ RNI T   Q   +F
Sbjct: 255 IAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIF 296



 Score = 57.0 bits (136), Expect = 2e-08,   Method: Compositional matrix adjust.
 Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 29/169 (17%)

Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY 200
           N  +   K + +F+ L  +Q + +++A      +EG+++I +G+ G  FY+I  G  +I 
Sbjct: 407 NNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEI- 465

Query: 201 VKCDGVGRCVGNYDNRGSFGELALMYNTPRAAT-ITATSPGALWGLDRVTFRRIIVKNNA 259
           VK     R +G  D    FGE AL+Y+ PR A+ I+  +    W +D+  F +II     
Sbjct: 466 VKNKKRLRTLGKND---YFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQII----- 517

Query: 260 KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYND---GEQIIAQG 305
                        P L  LE  ER+K+ D   TKV  D    E+II +G
Sbjct: 518 -----------QGPMLAHLE--ERIKMQD---TKVEMDELETERIIGRG 550



 Score = 54.7 bits (130), Expect = 7e-08,   Method: Compositional matrix adjust.
 Identities = 58/263 (22%), Positives = 115/263 (43%), Gaps = 24/263 (9%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVID-RGTFD 198
           RN + EA +   +FK    +Q++ + D    +      +++ +       Y+I   G  +
Sbjct: 283 RNIMTEALQQSEIFKQFSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVE 342

Query: 199 IYVKCDGVGRCVGNYDNRG-SFG-ELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
           +++    +G       +RG SFG +  L    P   TI +     +  +        +  
Sbjct: 343 LFLDDTSIGIL-----SRGMSFGDQYVLNQKQPFKHTIKSLEVCKIALITETCLADCLGN 397

Query: 257 NNAKKRKMY---ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFI 313
           NN      Y   +S I+ +   + L   +   +++   T  Y +G+ II +G++   F+I
Sbjct: 398 NNIDASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYI 457

Query: 314 VESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA-HAIGTVKCL 372
           +++GEV+I   +K    + +N            YFGE AL+ ++PR AS    +  V+C 
Sbjct: 458 IKNGEVEIVKNKKRLRTLGKN-----------DYFGERALLYDEPRTASVISKVNNVECW 506

Query: 373 AMDVQAFERLL-GPCMEIMKRNI 394
            +D   F +++ GP +  ++  I
Sbjct: 507 FVDKSVFLQIIQGPMLAHLEERI 529


>6FTF-B nrPDB
          Length = 304

 Score =  105 bits (263), Expect = 3e-23,   Method: Compositional matrix adjust.
 Identities = 77/293 (26%), Positives = 140/293 (47%), Gaps = 28/293 (9%)

Query: 109 RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAM 168
           RR +V +E  +P  E+          K++D+ N + +     +LF  L+ + +  V  AM
Sbjct: 4   RRRTVRSEGIDP--EKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVAGAM 61

Query: 169 FEKLVKEGEHVIDQGDDGDN-FYVIDRGTFDI-------YVKCDGVGRCVGNYDNRGSFG 220
                K  + +++ G    N  Y+I  G  DI       Y+K +G            + G
Sbjct: 62  QRATFKHDDCIMEAGQTTCNKLYIIQSGHADIIKEGQKVYLKTEGT-----------AVG 110

Query: 221 ELALMYNTPRAATITATSPGAL-WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLE 279
           EL LMY+TP  AT+   +   + W LDR T+R +++    ++R+ Y  F+ ++PFL  L+
Sbjct: 111 ELELMYDTPVVATVKVCTDELIAWVLDRDTYRNLVMGTAIRRRETYIQFLANVPFLGGLD 170

Query: 280 VSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEI 339
             E+L++ D + ++ ++ GE II  G+  +  +I+  G V++ + R    E       ++
Sbjct: 171 SYEKLQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEV-IGRDADGE-----PTKV 224

Query: 340 ARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKR 392
               +G + GEL  + N    A   A   V    ++ + FE  LGP ++++KR
Sbjct: 225 CEFTQGDHIGELEFLNNHRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKR 277


>6BQ8-A nrPDB
          Length = 152

 Score = 70.9 bits (172), Expect = 1e-12,   Method: Compositional matrix adjust.
 Identities = 40/130 (30%), Positives = 73/130 (56%), Gaps = 6/130 (4%)

Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
           + Y +F+ S+  LK+L   +  K++D +  + Y+ G+ II +G+   +FFI+  G+VK+T
Sbjct: 9   EQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 68

Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLAMDVQAFER 381
              +G  + +      I    +G+YFGE AL+++  R+A+  A    V CL +D + F +
Sbjct: 69  QSTEGHDQPQ-----LIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 123

Query: 382 LLGPCMEIMK 391
            +G   E+ K
Sbjct: 124 TVGTFEELQK 133



 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/110 (23%), Positives = 58/110 (52%), Gaps = 3/110 (2%)

Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVG 207
           + + L KNL  +++++++D +  +   +G+++I +G++G  F+++ +G   +    +G  
Sbjct: 16  RSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHD 75

Query: 208 --RCVGNYDNRGSFGELALMYNTPRAATITATSPG-ALWGLDRVTFRRII 254
             + +        FGE AL+ +  R+A I A     A   +DR TF + +
Sbjct: 76  QPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTV 125


>5H78-A nrPDB
          Length = 197

 Score = 67.8 bits (164), Expect = 8e-12,   Method: Compositional matrix adjust.
 Identities = 29/58 (50%), Positives = 41/58 (70%)

Query: 3  IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
          ++IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+ E   +   +   + +   D
Sbjct: 4  MQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRSERVNERVKQLAEKAKEATD 61


>4QX5-A nrPDB
          Length = 153

 Score = 65.9 bits (159), Expect = 3e-11,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 5/124 (4%)

Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
           K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FFI+  G V 
Sbjct: 7   KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66

Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE 380
           +T     + +      V +    +G +FGE AL     R A+  A   V CL +D  +F+
Sbjct: 67  VT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFK 121

Query: 381 RLLG 384
            L+G
Sbjct: 122 HLIG 125



 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 10/134 (7%)

Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
           +     E  K +  F++L  E +S++ D + E   + GE++I QG  GD F++I +GT +
Sbjct: 7   KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66

Query: 199 IYVKCDGVG------RCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
           +  + D         R +G  D    FGE AL     R A + A        +DR +F+ 
Sbjct: 67  V-TREDSPSEDPVFLRTLGKGD---WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKH 122

Query: 253 IIVKNNAKKRKMYE 266
           +I   +    K YE
Sbjct: 123 LIGGLDDVSNKAYE 136


>5JAX-A nrPDB
          Length = 135

 Score = 65.9 bits (159), Expect = 4e-11,   Method: Compositional matrix adjust.
 Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 5/124 (4%)

Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
           K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FFI+  G V 
Sbjct: 7   KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66

Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE 380
           +T     + +      V +    +G +FGE AL     R A+  A   V CL +D  +F+
Sbjct: 67  VT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFK 121

Query: 381 RLLG 384
            L+G
Sbjct: 122 HLIG 125



 Score = 49.3 bits (116), Expect = 3e-06,   Method: Compositional matrix adjust.
 Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 10/122 (8%)

Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
           +     E  K +  F++L  E +S++ D + E   + GE++I QG  GD F++I +GT +
Sbjct: 7   KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66

Query: 199 IYVKCDGVG------RCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
           +  + D         R +G  D    FGE AL     R A + A        +DR +F+ 
Sbjct: 67  V-TREDSPSEDPVFLRTLGKGD---WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKH 122

Query: 253 II 254
           +I
Sbjct: 123 LI 124


>5H77-A nrPDB
          Length = 90

 Score = 65.1 bits (157), Expect = 6e-11,   Method: Composition-based stats.
 Identities = 28/39 (71%), Positives = 36/39 (92%)

Query: 4  EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQE 42
          +IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+Q+
Sbjct: 5  QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRQQ 43


>5XBY-A nrPDB
          Length = 97

 Score = 62.8 bits (151), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 28/48 (58%), Positives = 38/48 (79%)

Query: 4  EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARF 51
          +IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL++   ++    F
Sbjct: 5  QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARNKEQQNAF 52


>5V4S-A nrPDB
          Length = 465

 Score = 51.2 bits (121), Expect = 8e-07,   Method: Compositional matrix adjust.
 Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 9/123 (7%)

Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
           K +++   +E +PFLK  + +    +V  +   ++ +G+ I  +G+  D  +I+  G V 
Sbjct: 332 KIQLHRDLLEKVPFLKGADPALVTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVD 391

Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE 380
           I         ++ +    +     GQ+FGELALV + PR+A+  A  T +   +    F+
Sbjct: 392 I---------LDSDEKTILLSLQEGQFFGELALVMDAPRSATVRATTTCEIYTLSKTDFD 442

Query: 381 RLL 383
            +L
Sbjct: 443 NVL 445



 Score = 50.8 bits (120), Expect = 1e-06,   Method: Compositional matrix adjust.
 Identities = 34/120 (28%), Positives = 60/120 (50%), Gaps = 9/120 (7%)

Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVG 211
             K  DP  ++ ++ +M   +  EG+ +  +G+ GD+ Y++  G+ DI    D   + + 
Sbjct: 345 FLKGADPALVTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVDI---LDSDEKTIL 401

Query: 212 NYDNRGS-FGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIE 270
                G  FGELAL+ + PR+AT+ AT+   ++ L +  F      N  K+   + S IE
Sbjct: 402 LSLQEGQFFGELALVMDAPRSATVRATTTCEIYTLSKTDF-----DNVLKRFSQFRSAIE 456


>6CJQ-A nrPDB
          Length = 456

 Score = 48.5 bits (114), Expect = 5e-06,   Method: Compositional matrix adjust.
 Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 11/132 (8%)

Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
           +  + + LFK    E +  ++  +   +   GE++I  G+ G + Y I+RG+ ++ +  D
Sbjct: 313 DVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEV-LSAD 371

Query: 205 GVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII---------V 255
              R     + +  FGE+AL+   PR AT+ A +   L+ LD+ TF RI+         +
Sbjct: 372 EKTRYAILSEGQ-FFGEMALILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQI 430

Query: 256 KNNAKKRKMYES 267
           +  A +RK  ES
Sbjct: 431 QELAVRRKELES 442



 Score = 45.8 bits (107), Expect = 4e-05,   Method: Compositional matrix adjust.
 Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 9/96 (9%)

Query: 294 VYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELAL 353
           +Y  GE II  G++    + +  G V++         +  +     A    GQ+FGE+AL
Sbjct: 340 IYGPGEYIIRAGEMGSDVYFINRGSVEV---------LSADEKTRYAILSEGQFFGEMAL 390

Query: 354 VTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEI 389
           +   PR A+  A        +D + F+R+L    EI
Sbjct: 391 ILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEI 426


>4MGY-E nrPDB
          Length = 694

 Score = 45.8 bits (107), Expect = 3e-05,   Method: Compositional matrix adjust.
 Identities = 40/138 (28%), Positives = 70/138 (50%), Gaps = 14/138 (10%)

Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
           DA  R+I  K   QR  + L+    ++L  K L         +++ VL  +FE   K G 
Sbjct: 8   DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 65

Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
            + +QG++G ++Y+I +G+ ++ +   GV   +   D+   FG+LAL+ + PRAA+I   
Sbjct: 66  VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGQLALVNDAPRAASIVLR 122

Query: 238 SPGA-LWGLDRVTFRRII 254
                   +D+  F RI+
Sbjct: 123 EDNCHFLRVDKEDFNRIL 140



 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 20/95 (21%)

Query: 291 GTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGE 350
           GT ++N GE+         S++I+  G V + +  KG           +     G  FG+
Sbjct: 64  GTVLFNQGEE-------GTSWYIILKGSVNVVIYGKGV----------VCTLHEGDDFGQ 106

Query: 351 LALVTNKPRAASAHAIGTVKC--LAMDVQAFERLL 383
           LALV + PRAAS   +    C  L +D + F R+L
Sbjct: 107 LALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 140


>1O7F-A nrPDB
          Length = 469

 Score = 45.1 bits (105), Expect = 5e-05,   Method: Compositional matrix adjust.
 Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 14/150 (9%)

Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
           DA  R+I  K   QR  + L+    ++L  K L         +++ VL  +FE   K G 
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370

Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
            + +QG++G ++Y+I +G+ ++ +   GV   +   D+   FG+LAL+ + PRAA+I   
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIVLR 427

Query: 238 SPGA-LWGLDRVTFRRIIVKNNAKKRKMYE 266
                   +D+  F RI+    A   ++ E
Sbjct: 428 EDNCHFLRVDKEDFNRILRDVEANTVRLKE 457



 Score = 40.0 bits (92), Expect = 0.002,   Method: Compositional matrix adjust.
 Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 8/109 (7%)

Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV-----K 202
           K +  F+   P  + Q+    + + +++G  +  QGD G N+Y +  G+ D+ V      
Sbjct: 45  KGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSH 104

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
            D V  C        +FGE +++ NTPR ATI       L  +++  F+
Sbjct: 105 QDAVTICTLGIGT--AFGE-SILDNTPRHATIVTRESSELLRIEQEDFK 150



 Score = 36.6 bits (83), Expect = 0.019,   Method: Compositional matrix adjust.
 Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 20/95 (21%)

Query: 291 GTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGE 350
           GT ++N GE+         S++I+  G V + +  KG           +     G  FG+
Sbjct: 369 GTVLFNQGEE-------GTSWYIILKGSVNVVIYGKGV----------VCTLHEGDDFGK 411

Query: 351 LALVTNKPRAASAHAIGTVKC--LAMDVQAFERLL 383
           LALV + PRAAS   +    C  L +D + F R+L
Sbjct: 412 LALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 445


>4EV0-A nrPDB
          Length = 216

 Score = 45.1 bits (105), Expect = 6e-05,   Method: Compositional matrix adjust.
 Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 6/82 (7%)

Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
           ++Y  G+ I  QGDL  + ++V SG+V++     G  E        +A    G+ FGE++
Sbjct: 25  RLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQE------RTLALLGPGELFGEMS 78

Query: 353 LVTNKPRAASAHAIGTVKCLAM 374
           L+    R+ASA A+   + LA+
Sbjct: 79  LLDEGERSASAVAVEDTELLAL 100



 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 1/104 (0%)

Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCV 210
           LF  L PE++   L     +L  +G+ +  QGD G   Y++  G   ++     G  R +
Sbjct: 6   LFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTL 65

Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
                   FGE++L+    R+A+  A     L  L R  +  +I
Sbjct: 66  ALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALI 109


>4F7Z-A nrPDB
          Length = 999

 Score = 44.7 bits (104), Expect = 7e-05,   Method: Compositional matrix adjust.
 Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 13/118 (11%)

Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
           DA  R+I  K   QR  + L+    ++L  K L         +++ VL  +FE   K G 
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370

Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATIT 235
            + +QG++G ++Y+I +G+ ++ +   GV   +   D+   FG+LAL+ + PRAA+I 
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIV 425



 Score = 40.4 bits (93), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 8/111 (7%)

Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV-----K 202
           K +  F+   P  + Q+    + + +++G  +  QGD G N+Y +  G+ D+ V      
Sbjct: 45  KGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSH 104

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRI 253
            D V  C        +FGE +++ NTPR ATI       L  +++  F+ +
Sbjct: 105 QDAVTICTLGIGT--AFGE-SILDNTPRHATIVTRESSELLRIEQEDFKAL 152



 Score = 35.4 bits (80), Expect = 0.047,   Method: Compositional matrix adjust.
 Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 17/72 (23%)

Query: 291 GTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGE 350
           GT ++N GE+         S++I+  G V + +  KG           +     G  FG+
Sbjct: 369 GTVLFNQGEE-------GTSWYIILKGSVNVVIYGKGV----------VCTLHEGDDFGK 411

Query: 351 LALVTNKPRAAS 362
           LALV + PRAAS
Sbjct: 412 LALVNDAPRAAS 423


>4AVC-A nrPDB
          Length = 333

 Score = 44.3 bits (103), Expect = 1e-04,   Method: Compositional matrix adjust.
 Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 7/69 (10%)

Query: 298 GEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNK 357
           G+ ++ QG+ A SF ++ SG  ++       S V ++G   IAR   G   GE+AL+ + 
Sbjct: 44  GQVLLRQGEPAVSFLLISSGSAEV-------SHVGDDGVAIIARALPGMIVGEIALLRDS 96

Query: 358 PRAASAHAI 366
           PR+A+   I
Sbjct: 97  PRSATVTTI 105



 Score = 37.4 bits (85), Expect = 0.012,   Method: Compositional matrix adjust.
 Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 8/105 (7%)

Query: 176 GEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATI 234
           G+ ++ QG+   +F +I  G+ ++ +V  DGV   +         GE+AL+ ++PR+AT+
Sbjct: 44  GQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVA-IIARALPGMIVGEIALLRDSPRSATV 102

Query: 235 TATSPGALWGLDRVTFRRIIVKNNAKKRKM------YESFIESLP 273
           T   P   W   R  F  ++      +R +        +F+  +P
Sbjct: 103 TTIEPLTGWTGGRGAFATMVHIPGVGERLLRTARQRLAAFVSPIP 147


>3DKW-A nrPDB
          Length = 227

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 2/117 (1%)

Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VK 202
           Q+  +   LF+ L P Q+ ++L +     + +G +V  QG+    FY +  G   IY + 
Sbjct: 8   QQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLT 67

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKNN 258
            +G  + +   + R +F E  +  +TP   AT  A  P  L+      + R +  N 
Sbjct: 68  PEGQEKILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLRQLQDNT 124


>4CHV-A nrPDB
          Length = 361

 Score = 42.4 bits (98), Expect = 4e-04,   Method: Compositional matrix adjust.
 Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 13/122 (10%)

Query: 268 FIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKG 327
            + ++P  + L  +  +++V  +  +    G  I   G+  D  F V  G V        
Sbjct: 229 LVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSV-------- 280

Query: 328 KSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCM 387
              V     VE+     G +FGE+AL++ +PR+A+  A  TV  L++    F+ L     
Sbjct: 281 --SVATPNPVELGP---GAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQMLCSSSP 335

Query: 388 EI 389
           EI
Sbjct: 336 EI 337



 Score = 41.6 bits (96), Expect = 6e-04,   Method: Compositional matrix adjust.
 Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 8/119 (6%)

Query: 135 KTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDR 194
           + D  RN   +    + LF+ L P  + +++ A+  + V  G  +   G+ GD  + +  
Sbjct: 220 RGDFVRN--WQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVE 277

Query: 195 GTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRI 253
           G+  +    + V    G +     FGE+AL+   PR+AT++A +  +L  L    F+ +
Sbjct: 278 GSVSVATP-NPVELGPGAF-----FGEMALISGEPRSATVSAATTVSLLSLHSADFQML 330


>5JON-A nrPDB
          Length = 517

 Score = 41.2 bits (95), Expect = 0.001,   Method: Compositional matrix adjust.
 Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 17/134 (12%)

Query: 250 FRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLAD 309
            R  IV  N +K       + S+P   + + +    ++  +  +V+  G+ II +G +  
Sbjct: 376 LREEIVNFNCRK------LVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGK 429

Query: 310 SFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTV 369
             + ++ G V +  K  G  E+         +   G YFGE+ L+T   R AS  A    
Sbjct: 430 KMYFIQHGVVSVLTK--GNKEM---------KLSDGSYFGEICLLTRGRRTASVRADTYC 478

Query: 370 KCLAMDVQAFERLL 383
           +  ++ V  F  +L
Sbjct: 479 RLYSLSVDNFNEVL 492



 Score = 39.7 bits (91), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 6/104 (5%)

Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCV- 210
           LF N DP  ++ +L  +  ++ + G+++I +G  G   Y I  G   +  K +   +   
Sbjct: 394 LFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSD 453

Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
           G+Y     FGE+ L+    R A++ A +   L+ L    F  ++
Sbjct: 454 GSY-----FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 492


>3I59-A nrPDB
          Length = 249

 Score = 39.3 bits (90), Expect = 0.003,   Method: Compositional matrix adjust.
 Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 12/110 (10%)

Query: 280 VSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEI 339
           ++++L+ VD      +  G  + A+G+  D  +I+ SG+VKI  +     +  EN    +
Sbjct: 47  LTKQLQPVD------FPRGHTVFAEGEPGDRLYIIISGKVKIGRR---APDGRENLLTIM 97

Query: 340 ARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEI 389
                   FGEL++    PR +SA  I  V+ ++MD  A    +    EI
Sbjct: 98  GPS---DMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEI 144



 Score = 33.9 bits (76), Expect = 0.14,   Method: Compositional matrix adjust.
 Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 1/104 (0%)

Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC-DGVGRCV 210
           +F+ ++P  ++ +   +       G  V  +G+ GD  Y+I  G   I  +  DG    +
Sbjct: 35  IFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLL 94

Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
                   FGEL++    PR ++ T  +      +DR   R  I
Sbjct: 95  TIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWI 138


>5W5B-A nrPDB
          Length = 236

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)

Query: 286 VVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM---KRKGKSEVEENGAVEIARC 342
           + + +  K +  G  +      AD  +IV  G +++ +   +R+    +   G V+    
Sbjct: 45  LAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAVVNILHPGDVD---- 100

Query: 343 FRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
                 G++ L+   P   +  A+    CL +D QAFERLL     I +R +++  +++
Sbjct: 101 ------GDIPLLLEMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSVAQRV 153


>4ORF-A nrPDB
          Length = 340

 Score = 39.3 bits (90), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 7/86 (8%)

Query: 298 GEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNK 357
           G+ +I QGD A +F ++ESG V++       S    +G   +     G   GE+AL+ + 
Sbjct: 48  GQVLIRQGDPALTFMLIESGRVQV-------SHAVADGPPIVLDIEPGLIIGEIALLRDA 100

Query: 358 PRAASAHAIGTVKCLAMDVQAFERLL 383
           P+ A+  A   V     D  AF+ +L
Sbjct: 101 PKTATVVAAEPVIGWVGDRDAFDTIL 126



 Score = 37.4 bits (85), Expect = 0.011,   Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 2/82 (2%)

Query: 174 KEGEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAA 232
           + G+ +I QGD    F +I+ G   + +   DG    V + +     GE+AL+ + P+ A
Sbjct: 46  EPGQVLIRQGDPALTFMLIESGRVQVSHAVADG-PPIVLDIEPGLIIGEIALLRDAPKTA 104

Query: 233 TITATSPGALWGLDRVTFRRII 254
           T+ A  P   W  DR  F  I+
Sbjct: 105 TVVAAEPVIGWVGDRDAFDTIL 126


>5U6P-A nrPDB
          Length = 660

 Score = 38.9 bits (89), Expect = 0.004,   Method: Compositional matrix adjust.
 Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 6/104 (5%)

Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCV- 210
           LF N DP  ++ +L  +  ++ + G+++I +G  G   Y I  G   +  K     +   
Sbjct: 475 LFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTD 534

Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
           G+Y     FGE+ L+    R A++ A +   L+ L    F  ++
Sbjct: 535 GSY-----FGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVL 573



 Score = 37.4 bits (85), Expect = 0.013,   Method: Compositional matrix adjust.
 Identities = 27/134 (20%), Positives = 56/134 (41%), Gaps = 17/134 (12%)

Query: 250 FRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLAD 309
            R  IV  N +K       + ++P   + + +    ++  +  +V+  G+ II +G +  
Sbjct: 457 LREEIVNFNCRK------LVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGK 510

Query: 310 SFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTV 369
             + ++ G   +  K   + ++ +           G YFGE+ L+T   R AS  A    
Sbjct: 511 KMYFIQHGVAGVITKSSKEMKLTD-----------GSYFGEICLLTKGRRTASVRADTYC 559

Query: 370 KCLAMDVQAFERLL 383
           +  ++ V  F  +L
Sbjct: 560 RLYSLSVDNFNEVL 573


>4CYD-A nrPDB
          Length = 225

 Score = 36.6 bits (83), Expect = 0.022,   Method: Compositional matrix adjust.
 Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 1/92 (1%)

Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
           +QE      +F+ +DP  ++ ++  M       G  + D+G+ GD  Y+I  G   +   
Sbjct: 2   VQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARH 61

Query: 203 C-DGVGRCVGNYDNRGSFGELALMYNTPRAAT 233
             DG    +        FGEL++    PR ++
Sbjct: 62  APDGRENLLTIMGPSDMFGELSIFDPGPRTSS 93



 Score = 29.6 bits (65), Expect = 2.6,   Method: Compositional matrix adjust.
 Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 6/81 (7%)

Query: 295 YNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALV 354
           +  G  I  +G+  D  +I+ SG+VK+    +   +  EN    +        FGEL++ 
Sbjct: 32  FPRGATIFDEGEPGDRLYIITSGKVKLA---RHAPDGRENLLTIMGPS---DMFGELSIF 85

Query: 355 TNKPRAASAHAIGTVKCLAMD 375
              PR +SA  +  V    M+
Sbjct: 86  DPGPRTSSAVCVTEVHAATMN 106


>2GAU-A nrPDB
          Length = 232

 Score = 35.8 bits (81), Expect = 0.039,   Method: Compositional matrix adjust.
 Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 8/84 (9%)

Query: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR-GQYFGELALVTNKPR 359
           + ++GD+ ++ F +  G++KI   R+G       G   I+R  + GQ+FG       +  
Sbjct: 44  VFSEGDIPNNLFYLYEGKIKIL--REGVY-----GRFHISRIVKPGQFFGMRPYFAEETC 96

Query: 360 AASAHAIGTVKCLAMDVQAFERLL 383
           +++A A+   K LA+ V+A E LL
Sbjct: 97  SSTAIAVENSKVLAIPVEAIEALL 120


>3H3Z-A nrPDB
          Length = 235

 Score = 33.1 bits (74), Expect = 0.24,   Method: Compositional matrix adjust.
 Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 8/105 (7%)

Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCF-RGQYFGEL 351
           + Y+ GE +  Q + A +  +V  G VK+         +   G+  +   F RG+ FGE 
Sbjct: 35  RSYDRGETLFLQEEKAQAIHVVIDGWVKLF-------RMTPTGSEAVVSVFTRGESFGEA 87

Query: 352 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIAT 396
             + N P   SA A+   + + +    F  L+    EI    +AT
Sbjct: 88  VALRNTPYPVSAEAVTPCEVMHIPSPVFVSLMRRDPEICISILAT 132



 Score = 31.6 bits (70), Expect = 0.68,   Method: Compositional matrix adjust.
 Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)

Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVG 207
           ++ LL ++L  + +  +L     +    GE +  Q +     +V+  G   ++       
Sbjct: 12  RNSLLIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKLFRMTPTGS 71

Query: 208 RCVGNYDNRG-SFGELALMYNTPRAATITATSP 239
             V +   RG SFGE   + NTP   +  A +P
Sbjct: 72  EAVVSVFTRGESFGEAVALRNTPYPVSAEAVTP 104


>4I0B-A nrPDB
          Length = 222

 Score = 32.0 bits (71), Expect = 0.56,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 179 VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSF-GELALM-YNTPRAATITA 236
           +I QG+  +  Y I +G+  + +K +     + +Y N+G F GEL L      R+A + A
Sbjct: 42  LIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRA 101

Query: 237 TSPGALWGLDRVTFRRIIVKN 257
            +   +  +    FR++I  N
Sbjct: 102 KTACEVAEISYKKFRQLIQVN 122


>3KCC-A nrPDB
          Length = 260

 Score = 31.6 bits (70), Expect = 0.63,   Method: Compositional matrix adjust.
 Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)

Query: 179 VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSF-GELALM-YNTPRAATITA 236
           +I QG+  +  Y I +G+  + +K +     + +Y N+G F GEL L      R+A + A
Sbjct: 80  LIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRA 139

Query: 237 TSPGALWGLDRVTFRRIIVKN 257
            +   +  +    FR++I  N
Sbjct: 140 KTACEVAEISYKKFRQLIQVN 160


>5H3O-A nrPDB
          Length = 738

 Score = 30.0 bits (66), Expect = 2.0,   Method: Compositional matrix adjust.
 Identities = 18/82 (21%), Positives = 42/82 (51%), Gaps = 4/82 (4%)

Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
           E  + + +F++ +   +++++  +  ++   G+ +  +GD G   Y++ RG   +    D
Sbjct: 491 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV---VD 547

Query: 205 GVGRCVGNYDNRGS-FGELALM 225
             G+ V      GS FGEL+++
Sbjct: 548 DDGKKVFVTLQEGSVFGELSIL 569



 Score = 28.9 bits (63), Expect = 4.5,   Method: Compositional matrix adjust.
 Identities = 15/62 (24%), Positives = 32/62 (51%), Gaps = 9/62 (14%)

Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
           +V++ G+ I  +GD+    +IV+ G +++         V+++G         G  FGEL+
Sbjct: 517 QVFSPGDFICKKGDIGREMYIVKRGRLQV---------VDDDGKKVFVTLQEGSVFGELS 567

Query: 353 LV 354
           ++
Sbjct: 568 IL 569


>5I62-A nrPDB
          Length = 534

 Score = 29.3 bits (64), Expect = 3.1,   Method: Compositional matrix adjust.
 Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 13/66 (19%)

Query: 207 GRCVGNYDNRGSFGELALM--YNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKM 264
           G CVG Y    + G LA+   Y  P            +WG   VT R + +  N K   +
Sbjct: 411 GMCVGVYSTMRALGRLAMQERYYDP-----------DVWGEKMVTLRYLSIIENVKYHPL 459

Query: 265 YESFIE 270
            E F++
Sbjct: 460 KEEFLD 465


>1DK5-A nrPDB
          Length = 322

 Score = 28.9 bits (63), Expect = 3.9,   Method: Compositional matrix adjust.
 Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 6/71 (8%)

Query: 127 AESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDG 186
           AES+I+H K  D+      A  D  + + L     +Q+   +     + GE ++ Q +DG
Sbjct: 178 AESKILHEKISDK------AYSDDEVIRILATRSKAQLNATLNHYKDEHGEDILKQLEDG 231

Query: 187 DNFYVIDRGTF 197
           D F  + R T 
Sbjct: 232 DEFVALLRATI 242


Searching..................................................done


Results from round 2


                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value
Sequences used in model and found again:

4X6Q-B nrPDB                                                          614   e-176
3J4Q-B nrPDB                                                          527   e-150
1CX4-A nrPDB                                                          449   e-126
4DIN-B nrPDB                                                          435   e-122
2QVS-B nrPDB                                                          426   e-120
6BYS-B nrPDB                                                          397   e-111
2QCS-B nrPDB                                                          352   1e-97
5KBF-A nrPDB                                                          343   7e-95
5J3U-A nrPDB                                                          312   2e-85
5FET-A nrPDB                                                          299   1e-81
5DYK-A nrPDB                                                          297   5e-81
6FTF-B nrPDB                                                          292   2e-79
4Z07-A nrPDB                                                          292   2e-79
3SHR-A nrPDB                                                          282   2e-76
5JAX-A nrPDB                                                          156   2e-38
4QX5-A nrPDB                                                          155   3e-38
6BQ8-A nrPDB                                                          140   1e-33
4MGY-E nrPDB                                                          139   2e-33
1O7F-A nrPDB                                                          139   2e-33
4F7Z-A nrPDB                                                          134   5e-32
5V4S-A nrPDB                                                          133   2e-31
6CJQ-A nrPDB                                                          128   4e-30
5JON-A nrPDB                                                          124   7e-29
4CHV-A nrPDB                                                          122   4e-28
3DKW-A nrPDB                                                          117   1e-26
4EV0-A nrPDB                                                          113   1e-25
4AVC-A nrPDB                                                           81   6e-16
5XBY-A nrPDB                                                           80   2e-15
5H78-A nrPDB                                                           79   2e-15
5H77-A nrPDB                                                           77   1e-14

Sequences not found previously or not previously below threshold:

5U6P-A nrPDB                                                          119   2e-27
4ORF-A nrPDB                                                           86   3e-17
4CYD-A nrPDB                                                           85   6e-17
3I59-A nrPDB                                                           84   7e-17
5H3O-A nrPDB                                                           77   2e-14
4I0B-A nrPDB                                                           74   1e-13
3KCC-A nrPDB                                                           74   1e-13
3E97-A nrPDB                                                           73   3e-13
5W5B-A nrPDB                                                           66   3e-11
5VA1-A nrPDB                                                           63   2e-10
2N7G-A nrPDB                                                           63   3e-10
2OZ6-A nrPDB                                                           62   4e-10
3H3Z-A nrPDB                                                           61   1e-09
3UKN-A nrPDB                                                           59   2e-09
5K7L-A nrPDB                                                           56   3e-08
4F8A-A nrPDB                                                           56   3e-08
3IWZ-A nrPDB                                                           53   4e-07
4L11-A nrPDB                                                           52   5e-07
2D93-A nrPDB                                                           47   1e-05
3B02-A nrPDB                                                           47   1e-05
2XKO-A nrPDB                                                           46   2e-05
3LA7-A nrPDB                                                           46   4e-05
1ZYB-A nrPDB                                                           45   5e-05
2GAU-A nrPDB                                                           45   7e-05
2FMY-A nrPDB                                                           43   2e-04
1O5L-A nrPDB                                                           41   7e-04
2ZCW-A nrPDB                                                           39   0.004
1ATT-A nrPDB                                                           37   0.019
4EB1-I nrPDB                                                           36   0.027
5E44-A nrPDB                                                           36   0.028
3E6B-A nrPDB                                                           34   0.089
4FHA-A nrPDB                                                           33   0.21 
1Z5V-A nrPDB                                                           32   0.50 
1XKW-A nrPDB                                                           32   0.52 
6CXO-A nrPDB                                                           29   3.0  
5MMI-U nrPDB                                                           29   4.4  

>4X6Q-B nrPDB
          Length = 416

 Score =  614 bits (1582), Expect = e-176,   Method: Composition-based stats.
 Identities = 415/416 (99%), Positives = 416/416 (100%)

Query: 1   MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
           MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD
Sbjct: 1   MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60

Query: 61  AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120
           AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP
Sbjct: 61  AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120

Query: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180
           DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI
Sbjct: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180

Query: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPG 240
           DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP+AATITATSPG
Sbjct: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPKAATITATSPG 240

Query: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300
           ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ
Sbjct: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300

Query: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360
           IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA
Sbjct: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360

Query: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416
           ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Sbjct: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416


>3J4Q-B nrPDB
          Length = 402

 Score =  527 bits (1357), Expect = e-150,   Method: Composition-based stats.
 Identities = 275/413 (66%), Positives = 328/413 (79%), Gaps = 17/413 (4%)

Query: 3   IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAG 62
           I+IPAGLTELLQG+TVEVLR QP DL++FA+++FTRL+ E  R+ +  F     T+    
Sbjct: 4   IQIPAGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLR-EARRQESDTFIVSPTTFHTQE 62

Query: 63  AAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDE 122
           ++A   I                E+GE +  +E      PV ++FTRR SVCAE +NPDE
Sbjct: 63  SSAVPVI---------------EEDGESDSDSEDADLEVPVPSKFTRRVSVCAETFNPDE 107

Query: 123 EEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQ 182
           EE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDAMFEK+VK  EHVIDQ
Sbjct: 108 EEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQ 167

Query: 183 GDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGAL 242
           GDDGDNFYVI+RGT+DI V  D   R VG YDNRGSFGELALMYNTPRAATI ATS G+L
Sbjct: 168 GDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSEGSL 227

Query: 243 WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQII 302
           WGLDRVTFRRIIVKNNAKKRKM+ESFIES+P  KSLE+SER+K+VDVIG K+Y DGE+II
Sbjct: 228 WGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERII 287

Query: 303 AQGDLADSFFIVESGEVKITMKRKGKS-EVEENGAVEIARCFRGQYFGELALVTNKPRAA 361
           AQG+ ADSF+I+ESGEV I ++ K KS +   N  VEIA C +GQYFGELALVTNKPRAA
Sbjct: 288 AQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAA 347

Query: 362 SAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEP 414
           SA+A+G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +FG+N+D+++P
Sbjct: 348 SAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLMDP 400


>1CX4-A nrPDB
          Length = 305

 Score =  449 bits (1155), Expect = e-126,   Method: Composition-based stats.
 Identities = 300/305 (98%), Positives = 303/305 (99%)

Query: 112 SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 171
           SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK
Sbjct: 1   SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 60

Query: 172 LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 231
           LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA
Sbjct: 61  LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 120

Query: 232 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 291
           ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG
Sbjct: 121 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 180

Query: 292 TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
           TKVYNDGEQIIAQGD ADSFFIVESGEV+ITMKRKGKS++EENGAVEIARC RGQYFGEL
Sbjct: 181 TKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGEL 240

Query: 352 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 411
           ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI
Sbjct: 241 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 300

Query: 412 VEPTA 416
           VEPTA
Sbjct: 301 VEPTA 305


>4DIN-B nrPDB
          Length = 381

 Score =  435 bits (1117), Expect = e-122,   Method: Composition-based stats.
 Identities = 144/390 (36%), Positives = 209/390 (53%), Gaps = 42/390 (10%)

Query: 8   GLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGG 67
           G+ ++L+   V +   +P   ++F  +HF +L++E  R+  AR                 
Sbjct: 26  GIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILAR----------------- 68

Query: 68  GIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA 127
                         +S+S++   +E       N PV+    RR  V AE Y   EE+  +
Sbjct: 69  -------------QKSNSQSDSHDEEVSPTPPN-PVVKARRRRGGVSAEVYT--EEDAVS 112

Query: 128 ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGD 187
             R + PK       L +A    +LF +LD  + S + DAMF      GE VI QG++GD
Sbjct: 113 YVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGD 172

Query: 188 NFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDR 247
           NFYV+D+G  D+YV  +     V N    GSFGELAL+Y TPRAAT+ A +   LWG+DR
Sbjct: 173 NFYVVDQGEVDVYVNGE----WVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDR 228

Query: 248 VTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDL 307
            ++RRI++ +  +KRKMYE F+  +  L+SLE  ERL V D +    + DGE+I+ QG+ 
Sbjct: 229 DSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEP 288

Query: 308 ADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIG 367
            D F+I+  G   +  +R    E      VE+ R     YFGE+AL+ N+PRAA+  A G
Sbjct: 289 GDDFYIITEGTASVLQRRSPNEEY-----VEVGRLGPSDYFGEIALLLNRPRAATVVARG 343

Query: 368 TVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
            +KC+ +D   FER+LGPC EI+KRNI  Y
Sbjct: 344 PLKCVKLDRPRFERVLGPCSEILKRNIQRY 373


>2QVS-B nrPDB
          Length = 310

 Score =  426 bits (1096), Expect = e-120,   Method: Composition-based stats.
 Identities = 233/308 (75%), Positives = 268/308 (87%), Gaps = 1/308 (0%)

Query: 108 TRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDA 167
           TRR SVCAE +NPDEEE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDA
Sbjct: 1   TRRVSVCAETFNPDEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDA 60

Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYN 227
           MFEK+VK  EHVIDQGDDGDNFYVI+RGT+DI V  D   R VG YDNRGSFGELALMYN
Sbjct: 61  MFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYN 120

Query: 228 TPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVV 287
           TPRAATI ATS G+LWGLDRVTFRRIIVKNNAKKRKM+ESFIES+P  KSLE+SER+K+V
Sbjct: 121 TPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIV 180

Query: 288 DVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKS-EVEENGAVEIARCFRGQ 346
           DVIG K+Y DGE+IIAQG+ ADSF+I+ESGEV I ++ K KS +   N  VEIA C +GQ
Sbjct: 181 DVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQ 240

Query: 347 YFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 406
           YFGELALVTNKPRAASA+ +G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +FG
Sbjct: 241 YFGELALVTNKPRAASAYGVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 300

Query: 407 TNMDIVEP 414
           +N+D+++P
Sbjct: 301 SNLDLMDP 308


>6BYS-B nrPDB
          Length = 379

 Score =  397 bits (1020), Expect = e-111,   Method: Composition-based stats.
 Identities = 136/389 (34%), Positives = 203/389 (52%), Gaps = 42/389 (10%)

Query: 9   LTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGG 68
           +  LL+   V++   +P   + F  ++F +L++E  ++                      
Sbjct: 25  IQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQN------------------- 65

Query: 69  IPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAE 128
                        ++ S     E+       N PV+    RR ++ AE Y   EE+  + 
Sbjct: 66  -----------LQKAGSRADSREDEISPPPPN-PVVKGRRRRGAISAEVYT--EEDAASY 111

Query: 129 SRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDN 188
            R + PK       L +A +  +LF +LD  + S + DAMF      GE VI QGD+GDN
Sbjct: 112 VRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDN 171

Query: 189 FYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRV 248
           FYVID+G  D+YV  +       +    GSFGELAL+Y TPRAAT+ A +   LWG+DR 
Sbjct: 172 FYVIDQGEMDVYVNNE----WATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRD 227

Query: 249 TFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLA 308
           ++RRI++ +  +KRKMYE F+  +  L+SL+  ERL V D +    + DG++I+ QG+  
Sbjct: 228 SYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPG 287

Query: 309 DSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT 368
           D FFI+  G   +  +R    E      VE+ R     YFGE+AL+ N+PRAA+  A G 
Sbjct: 288 DEFFIILEGSAAVLQRRSENEE-----FVEVGRLGPSDYFGEIALLMNRPRAATVVARGP 342

Query: 369 VKCLAMDVQAFERLLGPCMEIMKRNIATY 397
           +KC+ +D   FER+LGPC +I+KRNI  Y
Sbjct: 343 LKCVKLDRPRFERVLGPCSDILKRNIQQY 371



 Score =  111 bits (276), Expect = 9e-25,   Method: Composition-based stats.
 Identities = 46/177 (25%), Positives = 79/177 (44%), Gaps = 6/177 (3%)

Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
              +I    R A+V A+        + D+  RI+   T  +R   +E    + + ++LD 
Sbjct: 200 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDK 259

Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNY--DNR 216
            +   V DA+     ++G+ ++ QG+ GD F++I  G+  +  +       V        
Sbjct: 260 WERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPS 319

Query: 217 GSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV---KNNAKKRKMYESFIE 270
             FGE+AL+ N PRAAT+ A  P     LDR  F R++        +  + Y SF+ 
Sbjct: 320 DYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 376


>2QCS-B nrPDB
          Length = 291

 Score =  352 bits (903), Expect = 1e-97,   Method: Composition-based stats.
 Identities = 122/293 (41%), Positives = 173/293 (59%), Gaps = 11/293 (3%)

Query: 105 NRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQV 164
               RR ++ AE Y   EE+  +  R + PK       L +A +  +LF +LD  + S +
Sbjct: 1   KGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDI 58

Query: 165 LDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELAL 224
            DAMF      GE VI QGD+GDNFYVID+G  D+YV  +       +    GSFGELAL
Sbjct: 59  FDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNE----WATSVGEGGSFGELAL 114

Query: 225 MYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERL 284
           +Y TPRAAT+ A +   LWG+DR ++RRI++ +  +KRKMYE F+  +  L+SL+  ERL
Sbjct: 115 IYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERL 174

Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
            V D +    + DG++I+ QG+  D FFI+  G   +  +R    E      VE+ R   
Sbjct: 175 TVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEE-----FVEVGRLGP 229

Query: 345 GQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
             YFGE+AL+ N+P+AA+  A G +KC+ +D   FER+LGPC +I+KRNI  Y
Sbjct: 230 SDYFGEIALLMNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 282



 Score =  110 bits (275), Expect = 1e-24,   Method: Composition-based stats.
 Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 6/177 (3%)

Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
              +I    R A+V A+        + D+  RI+   T  +R   +E    + + ++LD 
Sbjct: 111 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDK 170

Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNY--DNR 216
            +   V DA+     ++G+ ++ QG+ GD F++I  G+  +  +       V        
Sbjct: 171 WERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPS 230

Query: 217 GSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV---KNNAKKRKMYESFIE 270
             FGE+AL+ N P+AAT+ A  P     LDR  F R++        +  + Y SF+ 
Sbjct: 231 DYFGEIALLMNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 287


>5KBF-A nrPDB
          Length = 301

 Score =  343 bits (880), Expect = 7e-95,   Method: Composition-based stats.
 Identities = 113/300 (37%), Positives = 174/300 (58%), Gaps = 12/300 (4%)

Query: 106 RFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVL 165
              +R SV AEAY    ++ D     ++ K + ++ +++EA  +  LF +L+ ++   ++
Sbjct: 3   GQKKRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIV 62

Query: 166 DAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELAL 224
           +A F+K V++G ++I++GD GD  YVID+G  +IY  K +     +    ++  FGELAL
Sbjct: 63  NAFFDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELAL 122

Query: 225 MYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERL 284
           +YN+ RAAT TA +   LW LDR +F  II    AKKRKMYE  +  +  LK ++  ER 
Sbjct: 123 LYNSKRAATATALTKCHLWALDRESFTYIIKDMVAKKRKMYEDILSHVNILKDMDPYERC 182

Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
           KV D + +K YNDGE II +G+  D+FFI+  G    +   K            I    +
Sbjct: 183 KVADCLKSKSYNDGEIIIKEGEEGDTFFILIDGNAVASKDNKV-----------IKTYTK 231

Query: 345 GQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVAL 404
           G YFGELAL+ NKPRAA+  A    + + +D ++F+RLLGP  +I+ RN+  Y++ L  L
Sbjct: 232 GDYFGELALLKNKPRAATIKAQNFCQVVYLDRKSFKRLLGPIEDILHRNVENYKKVLNEL 291


>5J3U-A nrPDB
          Length = 261

 Score =  312 bits (798), Expect = 2e-85,   Method: Composition-based stats.
 Identities = 95/266 (35%), Positives = 151/266 (56%), Gaps = 5/266 (1%)

Query: 132 IHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYV 191
           ++ K + Q+ +L+   +   LF +LD + ++ V+ AM EK ++    +I +GDDG+  Y+
Sbjct: 1   VYEKDEGQKEQLERILRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYI 60

Query: 192 IDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
           +  G  +     DG  R V       +FGELAL+YN PRAAT+T+ S   LW L R TF 
Sbjct: 61  VQSGELNCSKLIDGEERVVKVVGPGDAFGELALLYNAPRAATVTSVSACDLWELGRDTFN 120

Query: 252 RIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSF 311
            I+     K+R MY+SF++S+  L  ++  ER KV D + T+++ DG  I+ QG+L D F
Sbjct: 121 AIVKDAATKRRSMYDSFLKSVHILDGMDAYERGKVADALRTEMFTDGAYIVRQGELGDVF 180

Query: 312 FIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKC 371
           +IVE G    T     KS       +E+ +   G YFGELAL+  +PRAA+  A G  K 
Sbjct: 181 YIVEEGSAVAT-----KSFGPGQPPIEVKKYQAGDYFGELALINEEPRAANVIAHGICKV 235

Query: 372 LAMDVQAFERLLGPCMEIMKRNIATY 397
             ++ ++F+RL+G   +++ +  + Y
Sbjct: 236 ACLERKSFKRLMGSVQDLLSKKASEY 261



 Score =  112 bits (280), Expect = 3e-25,   Method: Composition-based stats.
 Identities = 47/174 (27%), Positives = 83/174 (47%), Gaps = 14/174 (8%)

Query: 99  FNAPVINRFTRRASVCA-EAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLD 157
           +NAP      R A+V +  A +  E   D  + I+      +R+      K + +   +D
Sbjct: 95  YNAP------RAATVTSVSACDLWELGRDTFNAIVKDAATKRRSMYDSFLKSVHILDGMD 148

Query: 158 PEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNYD 214
             +  +V DA+  ++  +G +++ QG+ GD FY+++ G+  +  K  G G+    V  Y 
Sbjct: 149 AYERGKVADALRTEMFTDGAYIVRQGELGDVFYIVEEGSA-VATKSFGPGQPPIEVKKYQ 207

Query: 215 NRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII---VKNNAKKRKMY 265
               FGELAL+   PRAA + A     +  L+R +F+R++       +KK   Y
Sbjct: 208 AGDYFGELALINEEPRAANVIAHGICKVACLERKSFKRLMGSVQDLLSKKASEY 261


>5FET-A nrPDB
          Length = 847

 Score =  299 bits (766), Expect = 1e-81,   Method: Composition-based stats.
 Identities = 82/282 (29%), Positives = 141/282 (50%), Gaps = 18/282 (6%)

Query: 124 EDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQG 183
           ED  + R    K  +    ++ + K+ L+   L+  ++  + + M   + K G+ VI QG
Sbjct: 27  EDHLQLR---EKLSEDIEMIKASLKNNLVCSTLNDNEILTLSNYMQFFVFKGGDLVIKQG 83

Query: 184 DDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALW 243
           + G  F++I+ G FD+YV      + V +     SFGE AL++NT R+ATI A + G LW
Sbjct: 84  EKGSYFFIINSGKFDVYVN----DKKVKSMGKGSSFGEAALIHNTQRSATIMAETDGTLW 139

Query: 244 GLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIA 303
           G+ R TFR  + + + +      SFI+S+     L  +++  + +    +++  GE I+ 
Sbjct: 140 GVQRSTFRATLKQLSNRNFNENRSFIDSVSVFDMLTEAQKNMITNACVIQMFKPGETIVK 199

Query: 304 QGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA 363
           QGD  D  FI++ G+  + +  K           EI    +G YFGE AL+ ++PR+A+ 
Sbjct: 200 QGDYGDVLFILKEGKATVFINDK-----------EIRVLNKGSYFGERALLYDEPRSATI 248

Query: 364 HAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALF 405
            A     C ++  +    +LG    ++ RNI T   Q   +F
Sbjct: 249 IAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIF 290



 Score =  128 bits (322), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 51/262 (19%), Positives = 112/262 (42%), Gaps = 22/262 (8%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFY-VIDRGTFD 198
           RN + EA +   +F+    EQ++ + D    +      H++ +       Y ++  G  +
Sbjct: 277 RNIMTEALQQSEIFRQFSAEQLNDLADTAIVRDYPANYHILHKDKVKSVKYLIVLEGKVE 336

Query: 199 IYVKCDGVGRCVGNYDNRGSFGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKN 257
           +++        +G      SFG+  ++    +   T+ +     +  +        +  N
Sbjct: 337 LFL----DDESIGILTRGKSFGDQYVLNQKQKFRHTVKSLDVCKIALITESCLADCLGDN 392

Query: 258 NA---KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIV 314
           N          +S I+ +   + L   +   +++   T  Y +G+ II +G++   F+I+
Sbjct: 393 NIDASIDHNNKKSIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYII 452

Query: 315 ESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLA 373
           ++GEV++T   K            +    +  YFGE AL+ ++PR AS  +   +V+C  
Sbjct: 453 KNGEVEVTKNGK-----------RLRTLGKNDYFGERALLYDEPRTASIISKATSVECWF 501

Query: 374 MDVQAFERLL-GPCMEIMKRNI 394
           +D   F +++ GP +  ++  I
Sbjct: 502 VDKSVFLQIIQGPMLTHLEERI 523



 Score =  120 bits (301), Expect = 1e-27,   Method: Composition-based stats.
 Identities = 52/289 (17%), Positives = 110/289 (38%), Gaps = 19/289 (6%)

Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
            A +I+   R A++ AE        +       +   ++   N  +     + +F  L  
Sbjct: 117 EAALIHNTQRSATIMAETDGTLWGVQRSTFRATLKQLSNRNFNENRSFIDSVSVFDMLTE 176

Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGS 218
            Q + + +A   ++ K GE ++ QGD GD  +++  G   +++      + +   +    
Sbjct: 177 AQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKEGKATVFIN----DKEIRVLNKGSY 232

Query: 219 FGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK-RKMYESFIESLPFLKS 277
           FGE AL+Y+ PR+ATI A  P A   + R     ++        R +    ++     + 
Sbjct: 233 FGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIFRQ 292

Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGD-LADSFFIVESGEVKITMKRKGKSEVEENGA 336
               +   + D    + Y     I+ +    +  + IV  G+V++ +  +          
Sbjct: 293 FSAEQLNDLADTAIVRDYPANYHILHKDKVKSVKYLIVLEGKVELFLDDES--------- 343

Query: 337 VEIARCFRGQYFGELALVTNKPR-AASAHAIGTVKCLAMDVQAFERLLG 384
             I    RG+ FG+  ++  K +   +  ++   K   +        LG
Sbjct: 344 --IGILTRGKSFGDQYVLNQKQKFRHTVKSLDVCKIALITESCLADCLG 390



 Score =  109 bits (271), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 29/200 (14%)

Query: 110 RASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMF 169
           + ++  E+   D   D+     I        N  +   K + +F+ L  +Q + +++A  
Sbjct: 376 KIALITESCLADCLGDNNIDASI------DHNNKKSIIKKMYIFRYLSEQQCNLLIEAFR 429

Query: 170 EKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP 229
               +EG+++I +G+ G  FY+I  G  ++        + +        FGE AL+Y+ P
Sbjct: 430 TTRYEEGDYIIQEGEVGSRFYIIKNGEVEVTKNG----KRLRTLGKNDYFGERALLYDEP 485

Query: 230 RAATITA-TSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVD 288
           R A+I +  +    W +D+  F +II                  P L  LE  ER+K+ D
Sbjct: 486 RTASIISKATSVECWFVDKSVFLQIIQG----------------PMLTHLE--ERIKMQD 527

Query: 289 VIGTKVYNDGEQIIAQGDLA 308
                   + E+II +G   
Sbjct: 528 TKVEMHELETERIIGRGTFG 547


>5DYK-A nrPDB
          Length = 853

 Score =  297 bits (760), Expect = 5e-81,   Method: Composition-based stats.
 Identities = 80/282 (28%), Positives = 139/282 (49%), Gaps = 18/282 (6%)

Query: 124 EDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQG 183
           ED  E R    K  +  + ++ + K+ L+   L+  ++  + + M   + K G  VI QG
Sbjct: 33  EDHLELR---EKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNYMQFFVFKSGNLVIKQG 89

Query: 184 DDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALW 243
           + G  F++I+ G FD+YV      + V       SFGE AL++NT R+ATI A + G LW
Sbjct: 90  EKGSYFFIINSGKFDVYVN----DKKVKTMGKGSSFGEAALIHNTQRSATIIAETDGTLW 145

Query: 244 GLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIA 303
           G+ R TFR  + + + +      +FI+S+     L  +++  + +    + +  GE I+ 
Sbjct: 146 GVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVK 205

Query: 304 QGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA 363
           QGD  D  +I++ G+  + +  +           EI    +G YFGE AL+ ++PR+A+ 
Sbjct: 206 QGDYGDVLYILKEGKATVYINDE-----------EIRVLEKGSYFGERALLYDEPRSATI 254

Query: 364 HAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALF 405
            A     C ++  +    +LG    ++ RNI T   Q   +F
Sbjct: 255 IAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIF 296



 Score =  126 bits (317), Expect = 1e-29,   Method: Composition-based stats.
 Identities = 55/290 (18%), Positives = 107/290 (36%), Gaps = 19/290 (6%)

Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
            A +I+   R A++ AE        +       +   ++   N  +     + +F  L  
Sbjct: 123 EAALIHNTQRSATIIAETDGTLWGVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTE 182

Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGS 218
            Q + + +A   +  K GE ++ QGD GD  Y++  G   +Y+  +     +   +    
Sbjct: 183 AQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEE----IRVLEKGSY 238

Query: 219 FGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK-RKMYESFIESLPFLKS 277
           FGE AL+Y+ PR+ATI A  P A   + R     ++        R +    ++     K 
Sbjct: 239 FGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIFKQ 298

Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVE-SGEVKITMKRKGKSEVEENGA 336
               +   + D    + Y     I+ +  +    +I+   G+V++ +             
Sbjct: 299 FSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVELFLDD----------- 347

Query: 337 VEIARCFRGQYFGELALVTNK-PRAASAHAIGTVKCLAMDVQAFERLLGP 385
             I    RG  FG+  ++  K P   +  ++   K   +        LG 
Sbjct: 348 TSIGILSRGMSFGDQYVLNQKQPFKHTIKSLEVCKIALITETCLADCLGN 397



 Score =  125 bits (314), Expect = 3e-29,   Method: Composition-based stats.
 Identities = 53/262 (20%), Positives = 112/262 (42%), Gaps = 22/262 (8%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVI-DRGTFD 198
           RN + EA +   +FK    +Q++ + D    +      +++ +       Y+I   G  +
Sbjct: 283 RNIMTEALQQSEIFKQFSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVE 342

Query: 199 IYVKCDGVGRCVGNYDNRGSFGELALMYN-TPRAATITATSPGALWGLDRVTFRRIIVKN 257
           +++        +G      SFG+  ++    P   TI +     +  +        +  N
Sbjct: 343 LFL----DDTSIGILSRGMSFGDQYVLNQKQPFKHTIKSLEVCKIALITETCLADCLGNN 398

Query: 258 NA---KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIV 314
           N          +S I+ +   + L   +   +++   T  Y +G+ II +G++   F+I+
Sbjct: 399 NIDASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYII 458

Query: 315 ESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLA 373
           ++GEV+I   +K            +    +  YFGE AL+ ++PR AS  + +  V+C  
Sbjct: 459 KNGEVEIVKNKK-----------RLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWF 507

Query: 374 MDVQAFERLL-GPCMEIMKRNI 394
           +D   F +++ GP +  ++  I
Sbjct: 508 VDKSVFLQIIQGPMLAHLEERI 529



 Score =  105 bits (262), Expect = 4e-23,   Method: Composition-based stats.
 Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 23/169 (13%)

Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY 200
           N  +   K + +F+ L  +Q + +++A      +EG+++I +G+ G  FY+I  G  +I 
Sbjct: 407 NNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIV 466

Query: 201 VKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATS-PGALWGLDRVTFRRIIVKNNA 259
                  + +        FGE AL+Y+ PR A++ +       W +D+  F +II     
Sbjct: 467 KN----KKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQG--- 519

Query: 260 KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLA 308
                        P L  LE  ER+K+ D        + E+II +G   
Sbjct: 520 -------------PMLAHLE--ERIKMQDTKVEMDELETERIIGRGTFG 553


>6FTF-B nrPDB
          Length = 304

 Score =  292 bits (747), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 73/289 (25%), Positives = 137/289 (47%), Gaps = 14/289 (4%)

Query: 106 RFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVL 165
              RR +V +E  +P  E+          K++D+ N + +     +LF  L+ + +  V 
Sbjct: 1   GRNRRRTVRSEGIDP--EKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVA 58

Query: 166 DAMFEKLVKEGEHVIDQGDDGDN-FYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELAL 224
            AM     K  + +++ G    N  Y+I  G  DI    +G    +       + GEL L
Sbjct: 59  GAMQRATFKHDDCIMEAGQTTCNKLYIIQSGHADII--KEGQKVYLKT--EGTAVGELEL 114

Query: 225 MYNTPRAATITATSPGAL-WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSER 283
           MY+TP  AT+   +   + W LDR T+R +++    ++R+ Y  F+ ++PFL  L+  E+
Sbjct: 115 MYDTPVVATVKVCTDELIAWVLDRDTYRNLVMGTAIRRRETYIQFLANVPFLGGLDSYEK 174

Query: 284 LKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCF 343
           L++ D + ++ ++ GE II  G+  +  +I+  G V++  +        +    ++    
Sbjct: 175 LQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEVIGRD------ADGEPTKVCEFT 228

Query: 344 RGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKR 392
           +G + GEL  + N    A   A   V    ++ + FE  LGP ++++KR
Sbjct: 229 QGDHIGELEFLNNHRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKR 277


>4Z07-A nrPDB
          Length = 262

 Score =  292 bits (747), Expect = 2e-79,   Method: Composition-based stats.
 Identities = 78/259 (30%), Positives = 128/259 (49%), Gaps = 9/259 (3%)

Query: 131 IIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFY 190
             +PK+   ++ ++EA  D    KNL+  Q+ +++D M+     +   +I +GD G   Y
Sbjct: 8   PFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVY 67

Query: 191 VIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTF 250
           V++ G  ++    +GV  C         FGELA++YN  R AT+       LW +DR  F
Sbjct: 68  VMEDGKVEV--TKEGVKLC--TMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 123

Query: 251 RRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADS 310
           + I+++    K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+
Sbjct: 124 QTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDT 183

Query: 311 FFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVK 370
           FFI+  G V +T     + +      V +    +G +FGE AL     R A+  A   V 
Sbjct: 184 FFIISKGTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVT 238

Query: 371 CLAMDVQAFERLLGPCMEI 389
           CL +D  +F+ L+G   ++
Sbjct: 239 CLVIDRDSFKHLIGGLDDV 257



 Score =  127 bits (319), Expect = 8e-30,   Method: Composition-based stats.
 Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 5/162 (3%)

Query: 108 TRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLD 166
           TR A+V           +      I+      +     E  K +  F++L  E +S++ D
Sbjct: 102 TRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLAD 161

Query: 167 AMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNYDNRGSFGELA 223
            + E   + GE++I QG  GD F++I +GT ++  + D        +        FGE A
Sbjct: 162 VLEETHYENGEYIIRQGARGDTFFIISKGTVNV-TREDSPSEDPVFLRTLGKGDWFGEKA 220

Query: 224 LMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMY 265
           L     R A + A        +DR +F+ +I   +    K Y
Sbjct: 221 LQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAY 262


>3SHR-A nrPDB
          Length = 299

 Score =  282 bits (722), Expect = 2e-76,   Method: Composition-based stats.
 Identities = 77/257 (29%), Positives = 128/257 (49%), Gaps = 9/257 (3%)

Query: 133 HPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVI 192
             K++  ++ ++EA  D    KNL+  Q+ +++D M+     +   +I +GD G   YV+
Sbjct: 27  FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 86

Query: 193 DRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
           + G  ++    +GV  C         FGELA++YN  R AT+       LW +DR  F+ 
Sbjct: 87  EDGKVEV--TKEGVKLC--TMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 142

Query: 253 IIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFF 312
           I+++    K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FF
Sbjct: 143 IMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFF 202

Query: 313 IVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCL 372
           I+  G+V +T     + +      V +    +G +FGE AL     R A+  A   V CL
Sbjct: 203 IISKGKVNVT-----REDSPNEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCL 257

Query: 373 AMDVQAFERLLGPCMEI 389
            +D  +F+ L+G   ++
Sbjct: 258 VIDRDSFKHLIGGLDDV 274



 Score =  129 bits (323), Expect = 3e-30,   Method: Composition-based stats.
 Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 3/163 (1%)

Query: 108 TRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLD 166
           TR A+V           +      I+      +     E  K +  F++L  E +S++ D
Sbjct: 119 TRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLAD 178

Query: 167 AMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV--KCDGVGRCVGNYDNRGSFGELAL 224
            + E   + GE++I QG  GD F++I +G  ++      +     +        FGE AL
Sbjct: 179 VLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPNEDPVFLRTLGKGDWFGEKAL 238

Query: 225 MYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYES 267
                R A + A        +DR +F+ +I   +    K YE 
Sbjct: 239 QGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYED 281


>5JAX-A nrPDB
          Length = 135

 Score =  156 bits (393), Expect = 2e-38,   Method: Composition-based stats.
 Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 5/133 (3%)

Query: 257 NNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVES 316
               K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FFI+  
Sbjct: 3   TGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISK 62

Query: 317 GEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDV 376
           G V +T     + +      V +    +G +FGE AL     R A+  A   V CL +D 
Sbjct: 63  GTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR 117

Query: 377 QAFERLLGPCMEI 389
            +F+ L+G   ++
Sbjct: 118 DSFKHLIGGLDDV 130



 Score =  121 bits (302), Expect = 8e-28,   Method: Composition-based stats.
 Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 4/130 (3%)

Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
           +     E  K +  F++L  E +S++ D + E   + GE++I QG  GD F++I +GT +
Sbjct: 7   KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66

Query: 199 IYVKCDGVGR---CVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV 255
           +  + D        +        FGE AL     R A + A        +DR +F+ +I 
Sbjct: 67  V-TREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIG 125

Query: 256 KNNAKKRKMY 265
             +    K Y
Sbjct: 126 GLDDVSNKAY 135


>4QX5-A nrPDB
          Length = 153

 Score =  155 bits (391), Expect = 3e-38,   Method: Composition-based stats.
 Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 5/133 (3%)

Query: 257 NNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVES 316
               K   Y  F++S+P  +SL      K+ DV+    Y +GE II QG   D+FFI+  
Sbjct: 3   TGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISK 62

Query: 317 GEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDV 376
           G V +T     + +      V +    +G +FGE AL     R A+  A   V CL +D 
Sbjct: 63  GTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR 117

Query: 377 QAFERLLGPCMEI 389
            +F+ L+G   ++
Sbjct: 118 DSFKHLIGGLDDV 130



 Score =  122 bits (306), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 4/132 (3%)

Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
           +     E  K +  F++L  E +S++ D + E   + GE++I QG  GD F++I +GT +
Sbjct: 7   KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66

Query: 199 IYVKCDGVGR---CVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV 255
           +  + D        +        FGE AL     R A + A        +DR +F+ +I 
Sbjct: 67  V-TREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIG 125

Query: 256 KNNAKKRKMYES 267
             +    K YE 
Sbjct: 126 GLDDVSNKAYED 137


>6BQ8-A nrPDB
          Length = 152

 Score =  140 bits (352), Expect = 1e-33,   Method: Composition-based stats.
 Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 6/132 (4%)

Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
           + + Y +F+ S+  LK+L   +  K++D +  + Y+ G+ II +G+   +FFI+  G+VK
Sbjct: 7   RDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVK 66

Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIG-TVKCLAMDVQAF 379
           +T   +G      +    I    +G+YFGE AL+++  R+A+  A    V CL +D + F
Sbjct: 67  VTQSTEGH-----DQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETF 121

Query: 380 ERLLGPCMEIMK 391
            + +G   E+ K
Sbjct: 122 NQTVGTFEELQK 133



 Score =  113 bits (282), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 26/118 (22%), Positives = 60/118 (50%), Gaps = 3/118 (2%)

Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY 200
            + +   + + L KNL  +++++++D +  +   +G+++I +G++G  F+++ +G   + 
Sbjct: 9   EQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 68

Query: 201 VKCDGVG--RCVGNYDNRGSFGELALMYNTPRAATITATS-PGALWGLDRVTFRRIIV 255
              +G    + +        FGE AL+ +  R+A I A     A   +DR TF + + 
Sbjct: 69  QSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVG 126


>4MGY-E nrPDB
          Length = 694

 Score =  139 bits (350), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 19/162 (11%)

Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
           DA  R+I  K   QR  + L+    ++L  K L         +++ VL  +FE   K G 
Sbjct: 8   DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 65

Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
            + +QG++G ++Y+I +G+ ++ +   GV   +   D+   FG+LAL+ + PRAA+I   
Sbjct: 66  VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGQLALVNDAPRAASIVLR 122

Query: 238 SP-GALWGLDRVTFRRIIVKNNAKKRKMYES-----FIESLP 273
                   +D+  F RI+    A   ++ E       +E +P
Sbjct: 123 EDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVP 164



 Score = 77.9 bits (190), Expect = 8e-15,   Method: Composition-based stats.
 Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 13/140 (9%)

Query: 265 YESFIESLPFLKSLEVSERLKVVDVIGTKVY-NDGEQIIAQGDLADSFFIVESGEVKITM 323
           Y+  +  +  L  L  + + ++  V+  + +   G  +  QG+   S++I+  G V + +
Sbjct: 31  YDELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVI 89

Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-VKCLAMDVQAFERL 382
             KG           +     G  FG+LALV + PRAAS          L +D + F R+
Sbjct: 90  YGKG----------VVCTLHEGDDFGQLALVNDAPRAASIVLREDNCHFLRVDKEDFNRI 139

Query: 383 LGPCMEIMKRNIATYEEQLV 402
           L        R     ++ LV
Sbjct: 140 LRDVEANTVRLKEHDQDVLV 159


>1O7F-A nrPDB
          Length = 469

 Score =  139 bits (349), Expect = 2e-33,   Method: Composition-based stats.
 Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 19/162 (11%)

Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
           DA  R+I  K   QR  + L+    ++L  K L         +++ VL  +FE   K G 
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370

Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
            + +QG++G ++Y+I +G+ ++ +   GV   +   D+   FG+LAL+ + PRAA+I   
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIVLR 427

Query: 238 SP-GALWGLDRVTFRRIIVKNNAKKRKMYES-----FIESLP 273
                   +D+  F RI+    A   ++ E       +E +P
Sbjct: 428 EDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVP 469



 Score = 89.1 bits (219), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 41/212 (19%), Positives = 85/212 (40%), Gaps = 20/212 (9%)

Query: 97  GAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNL 156
           G+   P++      +   AE     ++           ++ +  + +    K +  F+  
Sbjct: 1   GSPGIPMVAAHAAHSQSSAEWIACLDKRP-------LERSSEDVDIIFTRLKGVKAFEKF 53

Query: 157 DPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNY 213
            P  + Q+    + + +++G  +  QGD G N+Y +  G+ D+ V      +    +   
Sbjct: 54  HPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTL 113

Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
               +FGE +++ NTPR ATI       L  +++  F+ +      +K + Y + + + P
Sbjct: 114 GIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKALW-----EKYRQYMAGLLAPP 167

Query: 274 FLKSLEVSERLKVVDVIGTKVYNDGEQIIAQG 305
           +     V E     D I  K     E+I+  G
Sbjct: 168 Y----GVMETGSNNDRIPDKENVPSEKILRAG 195



 Score = 77.2 bits (188), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 13/140 (9%)

Query: 265 YESFIESLPFLKSLEVSERLKVVDVIGTKVY-NDGEQIIAQGDLADSFFIVESGEVKITM 323
           Y+  +  +  L  L  + + ++  V+  + +   G  +  QG+   S++I+  G V + +
Sbjct: 336 YDELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVI 394

Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-VKCLAMDVQAFERL 382
             KG           +     G  FG+LALV + PRAAS          L +D + F R+
Sbjct: 395 YGKG----------VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRI 444

Query: 383 LGPCMEIMKRNIATYEEQLV 402
           L        R     ++ LV
Sbjct: 445 LRDVEANTVRLKEHDQDVLV 464



 Score = 65.6 bits (158), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 5/114 (4%)

Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
           ++ +   +    +   ++      +    G  +  QGD+  +++ V +G + +    K  
Sbjct: 44  LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVS 99

Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERL 382
                  AV I     G  FGE +++ N PR A+     + + L ++ + F+ L
Sbjct: 100 ETSSHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKAL 152


>4F7Z-A nrPDB
          Length = 999

 Score =  134 bits (338), Expect = 5e-32,   Method: Composition-based stats.
 Identities = 43/162 (26%), Positives = 77/162 (47%), Gaps = 19/162 (11%)

Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
           DA  R+I  K   QR  + L+    ++L  K L         +++ VL  +FE   K G 
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370

Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
            + +QG++G ++Y+I +G+ ++ +   GV   +   D+   FG+LAL+ + PRAA+I   
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIVLR 427

Query: 238 SP-GALWGLDRVTFRRIIVKNNAKKRKMYES-----FIESLP 273
                   +D+    RI+    A   ++ E       +E +P
Sbjct: 428 EDNCHFLRVDKEDGNRILRDVEANTVRLKEHDQDVLVLEKVP 469



 Score = 89.1 bits (219), Expect = 3e-18,   Method: Composition-based stats.
 Identities = 41/212 (19%), Positives = 85/212 (40%), Gaps = 20/212 (9%)

Query: 97  GAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNL 156
           G+   P++      +   AE     ++           ++ +  + +    K +  F+  
Sbjct: 1   GSPGIPMVAAHAAHSQSSAEWIACLDKRP-------LERSSEDVDIIFTRLKGVKAFEKF 53

Query: 157 DPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNY 213
            P  + Q+    + + +++G  +  QGD G N+Y +  G+ D+ V      +    +   
Sbjct: 54  HPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTL 113

Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
               +FGE +++ NTPR ATI       L  +++  F+ +      +K + Y + + + P
Sbjct: 114 GIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKALW-----EKYRQYMAGLLAPP 167

Query: 274 FLKSLEVSERLKVVDVIGTKVYNDGEQIIAQG 305
           +     V E     D I  K     E+I+  G
Sbjct: 168 Y----GVMETGSNNDRIPDKENVPSEKILRAG 195



 Score = 72.5 bits (176), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 32/140 (22%), Positives = 57/140 (40%), Gaps = 13/140 (9%)

Query: 265 YESFIESLPFLKSLEVSERLKVVDVIGTKVY-NDGEQIIAQGDLADSFFIVESGEVKITM 323
           Y+  +  +  L  L  + + ++  V+  + +   G  +  QG+   S++I+  G V + +
Sbjct: 336 YDELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVI 394

Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-VKCLAMDVQAFERL 382
             KG           +     G  FG+LALV + PRAAS          L +D +   R+
Sbjct: 395 YGKG----------VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDGNRI 444

Query: 383 LGPCMEIMKRNIATYEEQLV 402
           L        R     ++ LV
Sbjct: 445 LRDVEANTVRLKEHDQDVLV 464



 Score = 65.6 bits (158), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 5/114 (4%)

Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
           ++ +   +    +   ++      +    G  +  QGD+  +++ V +G + +    K  
Sbjct: 44  LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVS 99

Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERL 382
                  AV I     G  FGE +++ N PR A+     + + L ++ + F+ L
Sbjct: 100 ETSSHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKAL 152


>5V4S-A nrPDB
          Length = 465

 Score =  133 bits (333), Expect = 2e-31,   Method: Composition-based stats.
 Identities = 33/155 (21%), Positives = 67/155 (43%), Gaps = 17/155 (10%)

Query: 242 LWGLDR---VTFRRIIVKNNA-----KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTK 293
           ++ +DR        ++           K +++   +E +PFLK  + +    +V  +   
Sbjct: 305 MYIIDRGWGEDENALLNDLPISLRREVKIQLHRDLLEKVPFLKGADPALVTSLVFSMKPM 364

Query: 294 VYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELAL 353
           ++ +G+ I  +G+  D  +I+  G V I          + +    +     GQ+FGELAL
Sbjct: 365 IFLEGDTIFRRGEKGDDLYILSEGSVDIL---------DSDEKTILLSLQEGQFFGELAL 415

Query: 354 VTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCME 388
           V + PR+A+  A  T +   +    F+ +L    +
Sbjct: 416 VMDAPRSATVRATTTCEIYTLSKTDFDNVLKRFSQ 450



 Score =  123 bits (309), Expect = 1e-28,   Method: Composition-based stats.
 Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 12/161 (7%)

Query: 121 DEEEDDAESR--IIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEH 178
             E+++A      I  + + +    ++  + +   K  DP  ++ ++ +M   +  EG+ 
Sbjct: 312 WGEDENALLNDLPISLRREVKIQLHRDLLEKVPFLKGADPALVTSLVFSMKPMIFLEGDT 371

Query: 179 VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGN-YDNRGSFGELALMYNTPRAATITAT 237
           +  +G+ GD+ Y++  G+ DI    D   + +         FGELAL+ + PR+AT+ AT
Sbjct: 372 IFRRGEKGDDLYILSEGSVDI---LDSDEKTILLSLQEGQFFGELALVMDAPRSATVRAT 428

Query: 238 SPGALWGLDRVTFRRIIVKNNAKKRKMYESFI-ESLPFLKS 277
           +   ++ L +  F      N  K+   + S I ES+  LK 
Sbjct: 429 TTCEIYTLSKTDF-----DNVLKRFSQFRSAIEESVAHLKK 464


>6CJQ-A nrPDB
          Length = 456

 Score =  128 bits (322), Expect = 4e-30,   Method: Composition-based stats.
 Identities = 33/151 (21%), Positives = 60/151 (39%), Gaps = 10/151 (6%)

Query: 259 AKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGE 318
           A   +++   IE +P  K         ++  +   +Y  GE II  G++    + +  G 
Sbjct: 305 AVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGS 364

Query: 319 VKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQA 378
           V++            +     A    GQ+FGE+AL+   PR A+  A        +D + 
Sbjct: 365 VEVL---------SADEKTRYAILSEGQFFGEMALILRAPRTATVRARAFCDLYRLDKET 415

Query: 379 FERLLGPCMEIMKRNIATYEEQLVALFGTNM 409
           F+R+L    EI  + I     +   L  + +
Sbjct: 416 FDRILSRYPEIAAQ-IQELAVRRKELESSGL 445



 Score =  122 bits (307), Expect = 2e-28,   Method: Composition-based stats.
 Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 17/163 (10%)

Query: 120 PDEEEDDAESRIIHPKTDD------QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLV 173
             E     E R +  +               +  + + LFK    E +  ++  +   + 
Sbjct: 282 LWETRRGYEEREVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIY 341

Query: 174 KEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAAT 233
             GE++I  G+ G + Y I+RG+ ++ +  D   R          FGE+AL+   PR AT
Sbjct: 342 GPGEYIIRAGEMGSDVYFINRGSVEV-LSADEKTRY-AILSEGQFFGEMALILRAPRTAT 399

Query: 234 ITATSPGALWGLDRVTFRRII---------VKNNAKKRKMYES 267
           + A +   L+ LD+ TF RI+         ++  A +RK  ES
Sbjct: 400 VRARAFCDLYRLDKETFDRILSRYPEIAAQIQELAVRRKELES 442


>5JON-A nrPDB
          Length = 517

 Score =  124 bits (311), Expect = 7e-29,   Method: Composition-based stats.
 Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 18/157 (11%)

Query: 250 FRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLAD 309
            R  IV  N +K       + S+P   + + +    ++  +  +V+  G+ II +G +  
Sbjct: 376 LREEIVNFNCRK------LVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGK 429

Query: 310 SFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTV 369
             + ++ G V +    KG  E+         +   G YFGE+ L+T   R AS  A    
Sbjct: 430 KMYFIQHGVVSVLT--KGNKEM---------KLSDGSYFGEICLLTRGRRTASVRADTYC 478

Query: 370 KCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 406
           +  ++ V  F  +L     +M+R   T     +   G
Sbjct: 479 RLYSLSVDNFNEVLEEYP-MMRRAFETVAIDRLDRIG 514



 Score = 86.0 bits (211), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 41/229 (17%), Positives = 77/229 (33%), Gaps = 17/229 (7%)

Query: 34  QHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEA 93
           +    + ++      A   +E     D   AA      KG      P  S          
Sbjct: 289 EGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAV 348

Query: 94  AEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLF 153
             A +    V        +  AE   P  EE    +              ++    + LF
Sbjct: 349 INAASGRQTVDEALKDAQTNAAELNGPLREEIVNFN-------------CRKLVASMPLF 395

Query: 154 KNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNY 213
            N DP  ++ +L  +  ++ + G+++I +G  G   Y I  G   +  K +   +     
Sbjct: 396 ANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMK----L 451

Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKR 262
            +   FGE+ L+    R A++ A +   L+ L    F  ++ +    +R
Sbjct: 452 SDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 500


>4CHV-A nrPDB
          Length = 361

 Score =  122 bits (305), Expect = 4e-28,   Method: Composition-based stats.
 Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 13/123 (10%)

Query: 267 SFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRK 326
             + ++P  + L  +  +++V  +  +    G  I   G+  D  F V  G V +     
Sbjct: 228 QLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSVSV----- 282

Query: 327 GKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPC 386
                     VE      G +FGE+AL++ +PR+A+  A  TV  L++    F+ L    
Sbjct: 283 -----ATPNPVE---LGPGAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQMLCSSS 334

Query: 387 MEI 389
            EI
Sbjct: 335 PEI 337



 Score =  109 bits (271), Expect = 3e-24,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 8/120 (6%)

Query: 134 PKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVID 193
            + D  RN   +    + LF+ L P  + +++ A+  + V  G  +   G+ GD  + + 
Sbjct: 219 RRGDFVRN--WQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVV 276

Query: 194 RGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRI 253
            G+  +                   FGE+AL+   PR+AT++A +  +L  L    F+ +
Sbjct: 277 EGSVSVATPN------PVELGPGAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQML 330


>5U6P-A nrPDB
          Length = 660

 Score =  119 bits (299), Expect = 2e-27,   Method: Composition-based stats.
 Identities = 32/166 (19%), Positives = 63/166 (37%), Gaps = 18/166 (10%)

Query: 247 RVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGD 306
               R  IV  N +K       + ++P   + + +    ++  +  +V+  G+ II +G 
Sbjct: 454 NDPLREEIVNFNCRK------LVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGA 507

Query: 307 LADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAI 366
           +    + ++ G   +  K   +            +   G YFGE+ L+T   R AS  A 
Sbjct: 508 VGKKMYFIQHGVAGVITKSSKEM-----------KLTDGSYFGEICLLTKGRRTASVRAD 556

Query: 367 GTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIV 412
              +  ++ V  F  +L     +M+R   T     +   G    I+
Sbjct: 557 TYCRLYSLSVDNFNEVLEEYP-MMRRAFETVAIDRLDRIGKKNSIL 601



 Score = 81.8 bits (200), Expect = 5e-16,   Method: Composition-based stats.
 Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 5/162 (3%)

Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
           ++    + LF N DP  ++ +L  +  ++ + G+++I +G  G   Y I  G   +  K 
Sbjct: 467 RKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKS 526

Query: 204 DGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 263
               +      +   FGE+ L+    R A++ A +   L+ L    F  ++ +    +R 
Sbjct: 527 SKEMK----LTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRA 582

Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGE-QIIAQ 304
                I+ L  +         K    + T V+N+ E +I+ Q
Sbjct: 583 FETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQ 624


>3DKW-A nrPDB
          Length = 227

 Score =  117 bits (292), Expect = 1e-26,   Method: Composition-based stats.
 Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 2/117 (1%)

Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VK 202
           Q+  +   LF+ L P Q+ ++L +     + +G +V  QG+    FY +  G   IY + 
Sbjct: 8   QQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLT 67

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKNN 258
            +G  + +   + R +F E  +  +TP   AT  A  P  L+      + R +  N 
Sbjct: 68  PEGQEKILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLRQLQDNT 124



 Score = 53.3 bits (126), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 22/122 (18%), Positives = 47/122 (38%), Gaps = 7/122 (5%)

Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
           ++++  ++S    + L   +  +++        + G  +  QG+ A +F+ + SG VKI 
Sbjct: 5   RVHQQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIY 64

Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPR-AASAHAIGTVKCLAMDVQAFER 381
                  E        +        F E  +  + P   A+A A+   +      +A+ R
Sbjct: 65  RLTPEGQE------KILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLR 118

Query: 382 LL 383
            L
Sbjct: 119 QL 120


>4EV0-A nrPDB
          Length = 216

 Score =  113 bits (283), Expect = 1e-25,   Method: Composition-based stats.
 Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 1/118 (0%)

Query: 147 CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDG 205
            K   LF  L PE++   L     +L  +G+ +  QGD G   Y++  G   ++     G
Sbjct: 1   MKGSPLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGG 60

Query: 206 VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 263
             R +        FGE++L+    R+A+  A     L  L R  +  +I +       
Sbjct: 61  QERTLALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALIRRLPLVAHN 118



 Score = 92.9 bits (229), Expect = 2e-19,   Method: Composition-based stats.
 Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 6/119 (5%)

Query: 273 PFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVE 332
           P    L   E    +     ++Y  G+ I  QGDL  + ++V SG+V++     G  E  
Sbjct: 5   PLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQE-- 62

Query: 333 ENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMK 391
                 +A    G+ FGE++L+    R+ASA A+   + LA+  + +  L+     +  
Sbjct: 63  ----RTLALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALIRRLPLVAH 117


>4ORF-A nrPDB
          Length = 340

 Score = 85.6 bits (210), Expect = 3e-17,   Method: Composition-based stats.
 Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 7/115 (6%)

Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
           + +L F      S    +   +       G+ +I QGD A +F ++ESG V++       
Sbjct: 19  LAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQV------- 71

Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLL 383
           S    +G   +     G   GE+AL+ + P+ A+  A   V     D  AF+ +L
Sbjct: 72  SHAVADGPPIVLDIEPGLIIGEIALLRDAPKTATVVAAEPVIGWVGDRDAFDTIL 126



 Score = 77.5 bits (189), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 32/160 (20%), Positives = 55/160 (34%), Gaps = 10/160 (6%)

Query: 136 TDDQRNRLQEA----CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYV 191
                  L E        +  F    P  +  +   +     + G+ +I QGD    F +
Sbjct: 4   DPGNVAELTEVRAADLAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFML 63

Query: 192 IDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
           I+ G   +          V + +     GE+AL+ + P+ AT+ A  P   W  DR  F 
Sbjct: 64  IESGRVQVSHAVADGPPIVLDIEPGLIIGEIALLRDAPKTATVVAAEPVIGWVGDRDAFD 123

Query: 252 RIIV------KNNAKKRKMYESFIESLPFLKSLEVSERLK 285
            I+       +     R+   +FI  +P          L+
Sbjct: 124 TILHLPGMFDRLVRIARQRLAAFITPIPVQVRTGEWFYLR 163


>4CYD-A nrPDB
          Length = 225

 Score = 84.9 bits (208), Expect = 6e-17,   Method: Composition-based stats.
 Identities = 23/115 (20%), Positives = 45/115 (39%), Gaps = 1/115 (0%)

Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
           +QE      +F+ +DP  ++ ++  M       G  + D+G+ GD  Y+I  G   +   
Sbjct: 2   VQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARH 61

Query: 203 -CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
             DG    +        FGEL++    PR ++    +      ++    R  +  
Sbjct: 62  APDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVAD 116



 Score = 77.2 bits (188), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 21/124 (16%), Positives = 45/124 (36%), Gaps = 6/124 (4%)

Query: 266 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKR 325
           +  +      + ++ +    ++  + T  +  G  I  +G+  D  +I+ SG+VK+    
Sbjct: 3   QEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLAR-- 60

Query: 326 KGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGP 385
                  +     +        FGEL++    PR +SA  +  V    M+       +  
Sbjct: 61  ----HAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVAD 116

Query: 386 CMEI 389
              I
Sbjct: 117 HPAI 120


>3I59-A nrPDB
          Length = 249

 Score = 84.5 bits (207), Expect = 7e-17,   Method: Composition-based stats.
 Identities = 25/115 (21%), Positives = 45/115 (39%), Gaps = 1/115 (0%)

Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
           + E      +F+ ++P  ++ +   +       G  V  +G+ GD  Y+I  G   I  +
Sbjct: 26  MDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRR 85

Query: 203 -CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
             DG    +        FGEL++    PR ++ T  +      +DR   R  I  
Sbjct: 86  APDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIAD 140



 Score = 82.9 bits (203), Expect = 2e-16,   Method: Composition-based stats.
 Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 6/124 (4%)

Query: 266 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKR 325
           +  +      + +E S    +   +    +  G  + A+G+  D  +I+ SG+VKI  + 
Sbjct: 27  DEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRA 86

Query: 326 KGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGP 385
               E        +        FGEL++    PR +SA  I  V+ ++MD  A    +  
Sbjct: 87  PDGREN------LLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIAD 140

Query: 386 CMEI 389
             EI
Sbjct: 141 RPEI 144


>4AVC-A nrPDB
          Length = 333

 Score = 81.4 bits (199), Expect = 6e-16,   Method: Composition-based stats.
 Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 7/111 (6%)

Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
           +  +   +       + +   +       G+ ++ QG+ A SF ++ SG  ++       
Sbjct: 15  LAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEV------- 67

Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAF 379
           S V ++G   IAR   G   GE+AL+ + PR+A+   I  +        AF
Sbjct: 68  SHVGDDGVAIIARALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAF 118



 Score = 72.1 bits (175), Expect = 4e-13,   Method: Composition-based stats.
 Identities = 26/136 (19%), Positives = 56/136 (41%), Gaps = 6/136 (4%)

Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
           E    + +F+    E +  +  ++       G+ ++ QG+   +F +I  G+ ++    D
Sbjct: 13  EDLAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGD 72

Query: 205 GVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII------VKNN 258
                +         GE+AL+ ++PR+AT+T   P   W   R  F  ++       +  
Sbjct: 73  DGVAIIARALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATMVHIPGVGERLL 132

Query: 259 AKKRKMYESFIESLPF 274
              R+   +F+  +P 
Sbjct: 133 RTARQRLAAFVSPIPV 148


>5XBY-A nrPDB
          Length = 97

 Score = 80.2 bits (196), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 28/50 (56%), Positives = 38/50 (76%)

Query: 4  EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGH 53
          +IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL++   ++    F  
Sbjct: 5  QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARNKEQQNAFYE 54


>5H78-A nrPDB
          Length = 197

 Score = 79.5 bits (194), Expect = 2e-15,   Method: Composition-based stats.
 Identities = 29/60 (48%), Positives = 41/60 (68%)

Query: 3  IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAG 62
          ++IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+ E   +   +   + +   D  
Sbjct: 4  MQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRSERVNERVKQLAEKAKEATDKE 63


>5H77-A nrPDB
          Length = 90

 Score = 77.2 bits (188), Expect = 1e-14,   Method: Composition-based stats.
 Identities = 33/82 (40%), Positives = 47/82 (57%)

Query: 4  EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGA 63
          +IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+Q+          +      +A  
Sbjct: 5  QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRQQRAFYEILHLPNLNEEQRNAFI 64

Query: 64 AAGGGIPSKGVNFAEEPMRSDS 85
           +    PS+  N   E  + + 
Sbjct: 65 QSLKDDPSQSANLLAEAKKLND 86


>5H3O-A nrPDB
          Length = 738

 Score = 76.8 bits (187), Expect = 2e-14,   Method: Composition-based stats.
 Identities = 22/135 (16%), Positives = 53/135 (39%), Gaps = 15/135 (11%)

Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
           +++   +  +   +  E     ++V  +  +V++ G+ I  +GD+    +IV+ G +++ 
Sbjct: 487 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV- 545

Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALV------TNKPRAASAHAIGTVKCLAMDV 376
                   V+++G         G  FGEL+++          R A+  ++G      +  
Sbjct: 546 --------VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSK 597

Query: 377 QAFERLLGPCMEIMK 391
                 L    +  K
Sbjct: 598 TDLWNALREYPDARK 612



 Score = 66.8 bits (161), Expect = 2e-11,   Method: Composition-based stats.
 Identities = 21/151 (13%), Positives = 57/151 (37%), Gaps = 11/151 (7%)

Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
           E  + + +F++ +   +++++  +  ++   G+ +  +GD G   Y++ RG   +    D
Sbjct: 491 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DD 548

Query: 205 GVGRCVGNYDNRGSFGELALM------YNTPRAATITATSPGALWGLDRVTFRRIIVKNN 258
              +          FGEL+++          R A + +     L+ L +      + +  
Sbjct: 549 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYP 608

Query: 259 AKKRKMY---ESFIESLPFLKSLEVSERLKV 286
             ++ +       ++    L      E+  V
Sbjct: 609 DARKLLLAKGREILKKDNLLDENAPEEQKTV 639


>4I0B-A nrPDB
          Length = 222

 Score = 73.7 bits (179), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 7/113 (6%)

Query: 290 IGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFG 349
                Y     +I QG+ A++ + +  G V + +K +   E+       ++   +G + G
Sbjct: 31  CHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEM------ILSYLNQGDFIG 84

Query: 350 ELALVTNK-PRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
           EL L      R+A   A    +   +  + F +L+    +I+ R  A    +L
Sbjct: 85  ELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRL 137



 Score = 63.3 bits (152), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 29/152 (19%), Positives = 56/152 (36%), Gaps = 15/152 (9%)

Query: 173 VKEGEHVIDQGDDGDNFYVIDRGTFDIYVK-CDGVGRCVGNYDNRGSFGELALMYNTP-R 230
                 +I QG+  +  Y I +G+  + +K  +G    +   +     GEL L      R
Sbjct: 36  YPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQER 95

Query: 231 AATITATSPGALWGLDRVTFRRIIVKN----------NAKKRKMYESFIESLPFLKSLE- 279
           +A + A +   +  +    FR++I  N           A++ ++    + +L FL     
Sbjct: 96  SAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGR 155

Query: 280 -VSERLKVVDVIGTKVYNDGEQI-IAQGDLAD 309
                L +          DG QI I + ++  
Sbjct: 156 IAQTLLNLAKQPDAMTLPDGMQIKITRQEIGQ 187


>3KCC-A nrPDB
          Length = 260

 Score = 73.7 bits (179), Expect = 1e-13,   Method: Composition-based stats.
 Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 7/113 (6%)

Query: 290 IGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFG 349
                Y     +I QG+ A++ + +  G V + +K +   E+       ++   +G + G
Sbjct: 69  CHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEM------ILSYLNQGDFIG 122

Query: 350 ELALVTNK-PRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
           EL L      R+A   A    +   +  + F +L+    +I+ R  A    +L
Sbjct: 123 ELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRL 175



 Score = 64.4 bits (155), Expect = 8e-11,   Method: Composition-based stats.
 Identities = 27/148 (18%), Positives = 51/148 (34%), Gaps = 5/148 (3%)

Query: 110 RASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMF 169
           R S   E      E    +S  +     D  ++       ++L K      +   L    
Sbjct: 14  RGSGMKETAAAKFERQHMDSPDL---GTDDDDKAMADIGSMVLGKPQTDPTLEWFLSHCH 70

Query: 170 EKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK-CDGVGRCVGNYDNRGSFGELALMYNT 228
                    +I QG+  +  Y I +G+  + +K  +G    +   +     GEL L    
Sbjct: 71  IHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG 130

Query: 229 P-RAATITATSPGALWGLDRVTFRRIIV 255
             R+A + A +   +  +    FR++I 
Sbjct: 131 QERSAWVRAKTACEVAEISYKKFRQLIQ 158


>3E97-A nrPDB
          Length = 231

 Score = 72.5 bits (176), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 30/149 (20%), Positives = 66/149 (44%), Gaps = 14/149 (9%)

Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
           ++  P  +++      + + V+  + +   E ++ Q    ++  +V +G V+++    G 
Sbjct: 8   LKRSPLFQNVPEDAMREALKVVTERNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGG 67

Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE-------R 381
            E              G   GE A++ ++ R+AS  A+  V+ L +  + FE       R
Sbjct: 68  RERVLGD-----IYAPG-VVGETAVLAHQERSASVRALTPVRTLMLHREHFELILRRHPR 121

Query: 382 LLGPCMEIMKRNIATYEEQLVALFGTNMD 410
           +L    E++ R +    ++L+A FG N +
Sbjct: 122 VLWNLAEMLARRVTFLNDELIA-FGQNTE 149



 Score = 72.5 bits (176), Expect = 3e-13,   Method: Composition-based stats.
 Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 1/132 (0%)

Query: 147 CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDG 205
            K   LF+N+  + M + L  + E+  +  E V++Q  +G+  +++  G   +  V   G
Sbjct: 8   LKRSPLFQNVPEDAMREALKVVTERNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGG 67

Query: 206 VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMY 265
             R +G+    G  GE A++ +  R+A++ A +P     L R  F  I+ ++      + 
Sbjct: 68  RERVLGDIYAPGVVGETAVLAHQERSASVRALTPVRTLMLHREHFELILRRHPRVLWNLA 127

Query: 266 ESFIESLPFLKS 277
           E     + FL  
Sbjct: 128 EMLARRVTFLND 139


>5W5B-A nrPDB
          Length = 236

 Score = 66.0 bits (159), Expect = 3e-11,   Method: Composition-based stats.
 Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%)

Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAV 337
           L   +   + + +  K +  G  +      AD  +IV  G +++ +  + +  V      
Sbjct: 37  LHRDDVSALAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAV------ 90

Query: 338 EIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
            +     G   G++ L+   P   +  A+    CL +D QAFERLL     I +R +++ 
Sbjct: 91  -VNILHPGDVDGDIPLLLEMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSV 149

Query: 398 EEQLV 402
            +++ 
Sbjct: 150 AQRVS 154


>5VA1-A nrPDB
          Length = 795

 Score = 62.9 bits (151), Expect = 2e-10,   Method: Composition-based stats.
 Identities = 17/127 (13%), Positives = 39/127 (30%), Gaps = 13/127 (10%)

Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM 323
           +  S ++     +         +     T     G+ ++  GDL  + + +  G ++I  
Sbjct: 492 LNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILR 551

Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAAS--AHAIGTVKCLAMDVQAFER 381
                        V +A   +   FGE   +  +P  ++    A+       +       
Sbjct: 552 GD-----------VVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE 600

Query: 382 LLGPCME 388
           +L    E
Sbjct: 601 VLDMYPE 607



 Score = 52.9 bits (125), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 18/113 (15%), Positives = 35/113 (30%), Gaps = 6/113 (5%)

Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
           +   +    F+      +  +           G+ ++  GD     Y I RG+ +I    
Sbjct: 494 RSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG- 552

Query: 204 DGVGRCVGNYDNRGSFGELALMYNTPRAAT--ITATSPGALWGLDRVTFRRII 254
                 V        FGE   +Y  P  +   + A +   L  + R     ++
Sbjct: 553 ---DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVL 602


>2N7G-A nrPDB
          Length = 154

 Score = 62.9 bits (151), Expect = 3e-10,   Method: Composition-based stats.
 Identities = 17/135 (12%), Positives = 39/135 (28%), Gaps = 13/135 (9%)

Query: 256 KNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVE 315
                  +   S ++     +         +     T     G+ ++  GDL  + + + 
Sbjct: 14  GTENLYFQSMRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFIS 73

Query: 316 SGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAAS--AHAIGTVKCLA 373
            G ++I               V +A   +   FGE   +  +P  ++    A+       
Sbjct: 74  RGSIEILRGD-----------VVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHK 122

Query: 374 MDVQAFERLLGPCME 388
           +       +L    E
Sbjct: 123 IHRDDLLEVLDMYPE 137



 Score = 53.7 bits (127), Expect = 2e-07,   Method: Composition-based stats.
 Identities = 18/114 (15%), Positives = 36/114 (31%), Gaps = 6/114 (5%)

Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
           ++   +    F+      +  +           G+ ++  GD     Y I RG+ +I   
Sbjct: 23  MRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG 82

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAAT--ITATSPGALWGLDRVTFRRII 254
                  V        FGE   +Y  P  +   + A +   L  + R     ++
Sbjct: 83  ----DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVL 132


>2OZ6-A nrPDB
          Length = 207

 Score = 62.1 bits (149), Expect = 4e-10,   Method: Composition-based stats.
 Identities = 25/110 (22%), Positives = 41/110 (37%), Gaps = 10/110 (9%)

Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
           K++     + Y     II  GD  ++ F +  G V I ++     E+       I     
Sbjct: 8   KLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM------IIGYLNS 61

Query: 345 GQYFGELALV----TNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIM 390
           G +FGEL L     + + R+A   A    +   +    F  L     EI+
Sbjct: 62  GDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEIL 111



 Score = 61.4 bits (147), Expect = 7e-10,   Method: Composition-based stats.
 Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 5/103 (4%)

Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK-CDGVGRCVGNYDNRG 217
           + + ++L     +       +I  GD  +  + I +G+  I ++  DG    +G  ++  
Sbjct: 4   KHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGD 63

Query: 218 SFGELALM----YNTPRAATITATSPGALWGLDRVTFRRIIVK 256
            FGEL L         R+A + A     +  +    FR +  +
Sbjct: 64  FFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 106


>3H3Z-A nrPDB
          Length = 235

 Score = 60.6 bits (145), Expect = 1e-09,   Method: Composition-based stats.
 Identities = 21/118 (17%), Positives = 46/118 (38%), Gaps = 1/118 (0%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI 199
               +   ++ LL ++L  + +  +L     +    GE +  Q +     +V+  G   +
Sbjct: 4   HEAQKAIARNSLLIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKL 63

Query: 200 Y-VKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
           + +   G    V  +    SFGE   + NTP   +  A +P  +  +    F  ++ +
Sbjct: 64  FRMTPTGSEAVVSVFTRGESFGEAVALRNTPYPVSAEAVTPCEVMHIPSPVFVSLMRR 121



 Score = 56.4 bits (134), Expect = 2e-08,   Method: Composition-based stats.
 Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)

Query: 274 FLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEE 333
            ++SL       ++     + Y+ GE +  Q + A +  +V  G VK+       SE   
Sbjct: 16  LIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKLFRMTPTGSE--- 72

Query: 334 NGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEI 389
                ++   RG+ FGE   + N P   SA A+   + + +    F  L+    EI
Sbjct: 73  ---AVVSVFTRGESFGEAVALRNTPYPVSAEAVTPCEVMHIPSPVFVSLMRRDPEI 125


>3UKN-A nrPDB
          Length = 212

 Score = 59.4 bits (142), Expect = 2e-09,   Method: Composition-based stats.
 Identities = 23/136 (16%), Positives = 48/136 (35%), Gaps = 13/136 (9%)

Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
           +  LP  +S        +  +I T     GE +I QGD   + + V SG +++       
Sbjct: 77  LLQLPLFESASRGCLRSLSLIIKTSFCAPGEFLIRQGDALQAIYFVCSGSMEVLKDN--- 133

Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKP--RAASAHAIGTVKCLAMDVQAFERLLGPC 386
                     +A   +G   G  +L   +     A+  A+       + ++    +L   
Sbjct: 134 --------TVLAILGKGDLIGSDSLTKEQVIKTNANVKALTYCDLQYISLKGLREVLRLY 185

Query: 387 MEIMKRNIATYEEQLV 402
            E  ++ ++  +  L 
Sbjct: 186 PEYAQKFVSEIQHDLT 201



 Score = 46.7 bits (109), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 17/115 (14%), Positives = 36/115 (31%), Gaps = 6/115 (5%)

Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
           L +    + LF++     +  +   +       GE +I QGD     Y +  G+ ++   
Sbjct: 73  LNKELLQLPLFESASRGCLRSLSLIIKTSFCAPGEFLIRQGDALQAIYFVCSGSMEVLK- 131

Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTP--RAATITATSPGALWGLDRVTFRRIIV 255
                  +         G  +L         A + A +   L  +     R ++ 
Sbjct: 132 ---DNTVLAILGKGDLIGSDSLTKEQVIKTNANVKALTYCDLQYISLKGLREVLR 183


>5K7L-A nrPDB
          Length = 857

 Score = 56.4 bits (134), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 17/131 (12%), Positives = 39/131 (29%), Gaps = 12/131 (9%)

Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
           ++  K+   F+      +  +           G+ +   G+  D+   +  G+ ++    
Sbjct: 546 RKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ-- 603

Query: 204 DGVGRCVGNYDNRGSFG-----ELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNN 258
                 V        FG     E  L       A + A +   L  + R   ++++    
Sbjct: 604 --DDEVVAILGKGDVFGDVFWKEATL---AQSCANVRALTYCDLHVIKRDALQKVLEFYT 658

Query: 259 AKKRKMYESFI 269
           A       + I
Sbjct: 659 AFSHSFSRNLI 669



 Score = 51.3 bits (121), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 25/150 (16%), Positives = 48/150 (32%), Gaps = 21/150 (14%)

Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM 323
           +     +  P  +         +     T     G+ I   G+  DS   V SG +++  
Sbjct: 544 LNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ 603

Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGEL----ALVTNKPRAASAHAIGTVKCLAMDVQAF 379
             +            +A   +G  FG++    A +      A+  A+       +   A 
Sbjct: 604 DDEV-----------VAILGKGDVFGDVFWKEATLAQS--CANVRALTYCDLHVIKRDAL 650

Query: 380 ERLL---GPCMEIMKRN-IATYEEQLVALF 405
           +++L           RN I TY  +   +F
Sbjct: 651 QKVLEFYTAFSHSFSRNLILTYNLRKRIVF 680


>4F8A-A nrPDB
          Length = 160

 Score = 56.4 bits (134), Expect = 3e-08,   Method: Composition-based stats.
 Identities = 17/131 (12%), Positives = 39/131 (29%), Gaps = 12/131 (9%)

Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
           ++  K+   F+      +  +           G+ +   G+  D+   +  G+ ++    
Sbjct: 26  RKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ-- 83

Query: 204 DGVGRCVGNYDNRGSFG-----ELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNN 258
                 V        FG     E  L       A + A +   L  + R   ++++    
Sbjct: 84  --DDEVVAILGKGDVFGDVFWKEATL---AQSCANVRALTYCDLHVIKRDALQKVLEFYT 138

Query: 259 AKKRKMYESFI 269
           A       + I
Sbjct: 139 AFSHSFSRNLI 149



 Score = 51.3 bits (121), Expect = 7e-07,   Method: Composition-based stats.
 Identities = 25/150 (16%), Positives = 48/150 (32%), Gaps = 21/150 (14%)

Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM 323
           +     +  P  +         +     T     G+ I   G+  DS   V SG +++  
Sbjct: 24  LNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ 83

Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGEL----ALVTNKPRAASAHAIGTVKCLAMDVQAF 379
             +            +A   +G  FG++    A +      A+  A+       +   A 
Sbjct: 84  DDEV-----------VAILGKGDVFGDVFWKEATLAQS--CANVRALTYCDLHVIKRDAL 130

Query: 380 ERLL---GPCMEIMKRN-IATYEEQLVALF 405
           +++L           RN I TY  +   +F
Sbjct: 131 QKVLEFYTAFSHSFSRNLILTYNLRKRIVF 160


>3IWZ-A nrPDB
          Length = 230

 Score = 52.5 bits (124), Expect = 4e-07,   Method: Composition-based stats.
 Identities = 16/103 (15%), Positives = 32/103 (31%), Gaps = 2/103 (1%)

Query: 155 NLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGV-GRCVGNY 213
            LD   + + L     +       V   GD     Y +  G+  I  + D      +G +
Sbjct: 21  TLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYF 80

Query: 214 DNRGSFGELALMYN-TPRAATITATSPGALWGLDRVTFRRIIV 255
            +    GE+ L      R   +   +   L  +     +++  
Sbjct: 81  GSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQ 123



 Score = 46.0 bits (107), Expect = 3e-05,   Method: Composition-based stats.
 Identities = 16/91 (17%), Positives = 36/91 (39%), Gaps = 7/91 (7%)

Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
           + Y     +   GD A + + V SG V I       +E +++  + +     G++ GE+ 
Sbjct: 37  RRYPTRTDVFRPGDPAGTLYYVISGSVSII------AEEDDDRELVLGYFGSGEFVGEMG 90

Query: 353 L-VTNKPRAASAHAIGTVKCLAMDVQAFERL 382
           L + +  R          +   +  +  ++L
Sbjct: 91  LFIESDTREVILRTRTQCELAEISYERLQQL 121


>4L11-A nrPDB
          Length = 204

 Score = 51.7 bits (122), Expect = 5e-07,   Method: Composition-based stats.
 Identities = 23/132 (17%), Positives = 47/132 (35%), Gaps = 10/132 (7%)

Query: 153 FKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGN 212
           F+   P  +  +           G+ ++ +GD     Y I RG+ +I          +  
Sbjct: 80  FEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIARGSIEILK----DDVVMAI 135

Query: 213 YDNRGSFGELALMYNT--PRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIE 270
                 FGE   +++T     + + A +   L  + R     ++        + Y+SF+ 
Sbjct: 136 LGKDDIFGENPCIHSTLGKSNSNVKALTYCDLHKIHRDDLLDVLDLFP----EFYDSFVN 191

Query: 271 SLPFLKSLEVSE 282
           SL    ++   E
Sbjct: 192 SLEITYNMRDEE 203



 Score = 47.1 bits (110), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 12/106 (11%), Positives = 32/106 (30%), Gaps = 13/106 (12%)

Query: 273 PFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVE 332
              ++        +     T     G+ ++ +GD+    + +  G ++I           
Sbjct: 78  SAFEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIARGSIEILKDD------- 130

Query: 333 ENGAVEIARCFRGQYFGELALVTN--KPRAASAHAIGTVKCLAMDV 376
               V +A   +   FGE   + +      ++  A+       +  
Sbjct: 131 ----VVMAILGKDDIFGENPCIHSTLGKSNSNVKALTYCDLHKIHR 172


>2D93-A nrPDB
          Length = 134

 Score = 47.5 bits (111), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 14/120 (11%)

Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAM-FEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI 199
            +L E    +  F N+      ++   M FE + + G  +++ G + D++YVI  GT +I
Sbjct: 12  EQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVILNGTVEI 71

Query: 200 YVKCDGVGRCVGNYDNRGSFG-----ELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
               DG    V N     SFG     +   M+   R              + +  + RI+
Sbjct: 72  S-HPDGK---VENLFMGNSFGITPTLDKQYMHGIVRT----KVDDCQFVCIAQQDYWRIL 123



 Score = 42.9 bits (99), Expect = 3e-04,   Method: Composition-based stats.
 Identities = 22/128 (17%), Positives = 49/128 (38%), Gaps = 13/128 (10%)

Query: 262 RKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYND-GEQIIAQGDLADSFFIVESGEVK 320
            +    F+  LP   ++ +S R ++  V+  +V    G  I+  G   DS++++ +G V+
Sbjct: 11  IEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVILNGTVE 70

Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLAMDVQAF 379
           I            +   ++   F G  FG    +  +         +   + + +  Q +
Sbjct: 71  I-----------SHPDGKVENLFMGNSFGITPTLDKQYMHGIVRTKVDDCQFVCIAQQDY 119

Query: 380 ERLLGPCM 387
            R+L    
Sbjct: 120 WRILNHVE 127


>3B02-A nrPDB
          Length = 195

 Score = 47.1 bits (110), Expect = 1e-05,   Method: Composition-based stats.
 Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 11/113 (9%)

Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
           K +   E I  +G+ A + + +E G V++         + +   + +     G YFGE A
Sbjct: 2   KRFARKETIYLRGEEARTLYRLEEGLVRVV------ELLPDGRLITLRHVLPGDYFGEEA 55

Query: 353 LVTNKPR-AASAHAIGTVKCL---AMDVQAFERLLGPCMEIMKRNIATYEEQL 401
           L     R  A A     V+ L   AMD +A  R+       M+R +  YE  L
Sbjct: 56  LEGKAYRYTAEAMTEAVVQGLEPRAMDHEALHRVARNLARQMRR-VQAYEAHL 107



 Score = 37.9 bits (86), Expect = 0.008,   Method: Composition-based stats.
 Identities = 18/108 (16%), Positives = 38/108 (35%), Gaps = 7/108 (6%)

Query: 171 KLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELALMYNTP 229
           K     E +  +G++    Y ++ G   +  +  DG    + +      FGE AL     
Sbjct: 2   KRFARKETIYLRGEEARTLYRLEEGLVRVVELLPDGRLITLRHVLPGDYFGEEALEGKAY 61

Query: 230 R-AATITATSPGALW---GLDRVTFRRIIVKNN--AKKRKMYESFIES 271
           R  A     +         +D     R+        ++ + YE+ +++
Sbjct: 62  RYTAEAMTEAVVQGLEPRAMDHEALHRVARNLARQMRRVQAYEAHLQT 109


>2XKO-A nrPDB
          Length = 222

 Score = 46.3 bits (108), Expect = 2e-05,   Method: Composition-based stats.
 Identities = 16/81 (19%), Positives = 32/81 (39%), Gaps = 3/81 (3%)

Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELALMY 226
           +  +  + G+ +   GD  +  Y++ +G   +  V   G    V        FG L+L+ 
Sbjct: 22  LQIEQFERGKTIFFPGDPAERVYLLVKGAVKLSRVYESGEEITVALLRENSVFGVLSLLT 81

Query: 227 N--TPRAATITATSPGALWGL 245
              + R     A +P  L+ +
Sbjct: 82  GQRSDRFYHAVAFTPVQLFSV 102


>3LA7-A nrPDB
          Length = 243

 Score = 45.6 bits (106), Expect = 4e-05,   Method: Composition-based stats.
 Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 11/121 (9%)

Query: 292 TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
            + +   + I   GD A+  + +  G VK++   +   E      + +A       FG L
Sbjct: 45  VETFERNKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEE------ITVALLRENSVFGVL 98

Query: 352 ALVTNKP--RAASAHAIGTVKCLAMDVQAFERLLGPCME---IMKRNIATYEEQLVALFG 406
           +L+T     R   A A   V+ L+  ++  E+ L    E   +M R +++   Q   +  
Sbjct: 99  SLLTGNKSDRFYHAVAFTPVELLSAPIEQVEQALKENPELSMLMLRGLSSRILQTEMMIE 158

Query: 407 T 407
           T
Sbjct: 159 T 159



 Score = 44.4 bits (103), Expect = 8e-05,   Method: Composition-based stats.
 Identities = 18/96 (18%), Positives = 29/96 (30%), Gaps = 5/96 (5%)

Query: 154 KNLDPEQMSQVLDAMFEK--LVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCV 210
           K L          A        +  + +   GD  +  Y + +G   +  V   G    V
Sbjct: 27  KALANVFRQMATGAFPPVVETFERNKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEEITV 86

Query: 211 GNYDNRGSFGELALM--YNTPRAATITATSPGALWG 244
                   FG L+L+    + R     A +P  L  
Sbjct: 87  ALLRENSVFGVLSLLTGNKSDRFYHAVAFTPVELLS 122


>1ZYB-A nrPDB
          Length = 232

 Score = 45.2 bits (105), Expect = 5e-05,   Method: Composition-based stats.
 Identities = 24/141 (17%), Positives = 43/141 (30%), Gaps = 19/141 (13%)

Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDA--MFEKLVKEGEHVIDQGDDGDNFYVIDRGTF 197
              + +    + LF+ L  E  + +LD   +     K GE +I  G+       + +G  
Sbjct: 13  METMFDTLLQLPLFQGLCHEDFTSILDKVKLHFIKHKAGETIIKSGNPCTQLCFLLKGEI 72

Query: 198 DIYVKCDGVGRCVGN-------YDNRGSFGELALMYNTPRAATITATSPGALWGLDR--- 247
            I          V          + +  FG      NT  A++  A +      + +   
Sbjct: 73  SIVTNAKENIYTVIEQIEAPYLIEPQSLFG-----MNTNYASSYVAHTEVHTVCISKAFV 127

Query: 248 --VTFRRIIVKNNAKKRKMYE 266
               FR  I + N        
Sbjct: 128 LSDLFRYDIFRLNYMNIVSNR 148



 Score = 41.3 bits (95), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 21/116 (18%), Positives = 38/116 (32%), Gaps = 8/116 (6%)

Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIG--TKVYNDGEQIIAQGDLADSFFIVESGEVK 320
            M+++ ++ LP  + L   +   ++D +      +  GE II  G+       +  GE+ 
Sbjct: 15  TMFDTLLQ-LPLFQGLCHEDFTSILDKVKLHFIKHKAGETIIKSGNPCTQLCFLLKGEIS 73

Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDV 376
           I    K                     FG      N   A+S  A   V  + +  
Sbjct: 74  IVTNAKENIYTVIEQIEAPYLIEPQSLFG-----MNTNYASSYVAHTEVHTVCISK 124


>2GAU-A nrPDB
          Length = 232

 Score = 44.8 bits (104), Expect = 7e-05,   Method: Composition-based stats.
 Identities = 25/150 (16%), Positives = 48/150 (32%), Gaps = 17/150 (11%)

Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC-DGVGRCVGNYDNRGSFGELALMY 226
           +     K+   V  +GD  +N + +  G   I  +   G             FG      
Sbjct: 33  IQPFPCKKASTVFSEGDIPNNLFYLYEGKIKILREGVYGRFHISRIVKPGQFFGMRPYFA 92

Query: 227 NTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKV 286
               ++T  A     +  +       ++  N          F+++L   K L  +ER  V
Sbjct: 93  EETCSSTAIAVENSKVLAIPVEAIEALLKGNT----SFCRYFLKALA--KELGYAERRTV 146

Query: 287 VDVIGTKVYNDGEQIIAQGDLADSFFIVES 316
              +  K          +G LA++  I++ 
Sbjct: 147 T--LTQKHV--------RGRLAETLLILKE 166



 Score = 39.4 bits (90), Expect = 0.003,   Method: Composition-based stats.
 Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 6/88 (6%)

Query: 296 NDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVT 355
                + ++GD+ ++ F +  G++KI  +                    GQ+FG      
Sbjct: 39  KKASTVFSEGDIPNNLFYLYEGKIKILREGVYGRFHIS------RIVKPGQFFGMRPYFA 92

Query: 356 NKPRAASAHAIGTVKCLAMDVQAFERLL 383
            +  +++A A+   K LA+ V+A E LL
Sbjct: 93  EETCSSTAIAVENSKVLAIPVEAIEALL 120


>2FMY-A nrPDB
          Length = 220

 Score = 42.9 bits (99), Expect = 2e-04,   Method: Composition-based stats.
 Identities = 21/118 (17%), Positives = 41/118 (34%), Gaps = 7/118 (5%)

Query: 147 CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGV 206
             D  L + L+ E+ S VL    E+   +   +     + +  +++  G   +Y+  +  
Sbjct: 6   LTDTNLLEVLNSEEYSGVLKEFREQRYSKKAILYTPNTERNLVFLVKSGRVRVYLAYEDK 65

Query: 207 GRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKM 264
              +   +    F        T   A I A     +   D   F+ I+V+  A    M
Sbjct: 66  EFTLAILEAGDIFC-------THTRAFIQAMEDTTILYTDIRNFQNIVVEFPAFSLNM 116


>1O5L-A nrPDB
          Length = 213

 Score = 41.3 bits (95), Expect = 7e-04,   Method: Composition-based stats.
 Identities = 17/116 (14%), Positives = 44/116 (37%), Gaps = 6/116 (5%)

Query: 160 QMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGS 218
            + ++L      + ++GE V  Q D  ++  ++  GT    +V  +G    +        
Sbjct: 14  DLKKLLPCGKVIVFRKGEIVKHQDDPIEDVLILLEGTLKTEHVSENGKTLEIDEIKPVQI 73

Query: 219 FGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
                +  + PR    + A     +  + +  F  +++    K R++   F++ + 
Sbjct: 74  IASGFIFSSEPRFPVNVVAGENSKILSIPKEVFLDLLM----KDRELLLFFLKDVS 125



 Score = 38.3 bits (87), Expect = 0.007,   Method: Composition-based stats.
 Identities = 21/107 (19%), Positives = 41/107 (38%), Gaps = 7/107 (6%)

Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
           K++      V+  GE +  Q D  +   I+  G +K     +    +E +    +     
Sbjct: 17  KLLPCGKVIVFRKGEIVKHQDDPIEDVLILLEGTLKTEHVSENGKTLEIDEIKPVQIIAS 76

Query: 345 GQYFGELALVTNKPR-AASAHAIGTVKCLAMDVQAFERLLGPCMEIM 390
           G  F      +++PR   +  A    K L++  + F  LL    E++
Sbjct: 77  GFIF------SSEPRFPVNVVAGENSKILSIPKEVFLDLLMKDRELL 117


>2ZCW-A nrPDB
          Length = 202

 Score = 39.0 bits (89), Expect = 0.004,   Method: Composition-based stats.
 Identities = 18/77 (23%), Positives = 26/77 (33%), Gaps = 4/77 (5%)

Query: 169 FEKLVKEGEHVIDQGDDG--DNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALM 225
                K G+ ++  G  G  D  Y +  G   +  V  +G    +      G FGE AL 
Sbjct: 6   ETVSFKAGDVILYPGVPGPRDRAYRVLEGLVRLEAVDEEGNALTLRLVRPGGFFGEEALF 65

Query: 226 YNTPRAATITATSPGAL 242
               R     A +   L
Sbjct: 66  -GQERIYFAEAATDVRL 81


>1ATT-A nrPDB
          Length = 429

 Score = 36.7 bits (83), Expect = 0.019,   Method: Composition-based stats.
 Identities = 28/159 (17%), Positives = 57/159 (35%), Gaps = 22/159 (13%)

Query: 105 NRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQV 164
               RR +   +      + DD    +I PK +    ++++     +L + LD    + +
Sbjct: 254 KFRYRRVAESTQVLELPFKGDDITMVLILPKLEKTLAKVEQELTPDMLQEWLDELTETLL 313

Query: 165 LDAMFEKLVKEGEHVIDQ-GDDG-DNFY---------VIDRGTFDIYVKCDGVGRCVGNY 213
           +  M    +++   V +Q  D G ++ +         ++  G  D+YV        +   
Sbjct: 314 VVHMPRFRIEDSFSVKEQLQDMGLEDLFSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVN 373

Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
           +      E A        A+   +  G     DRVTF+ 
Sbjct: 374 EEGS---EAA--------ASTVISIAGRSLNSDRVTFKA 401


>4EB1-I nrPDB
          Length = 440

 Score = 36.3 bits (82), Expect = 0.027,   Method: Composition-based stats.
 Identities = 32/181 (17%), Positives = 62/181 (34%), Gaps = 31/181 (17%)

Query: 105 NRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQV 164
               RR +   +      + DD    +I PK +    ++++     +L + LD  +   +
Sbjct: 265 KFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMML 324

Query: 165 LDAMFEKLVKEGEHVIDQ-GDDG--DNFY--------VIDRGTFDIYVKCDGVGRCVGNY 213
           +  M    +++G  + +Q  D G  D F         ++  G  D+YV        +   
Sbjct: 325 VVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVN 384

Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
           +      E A        A+      G     +RVTF+           + +  FI  +P
Sbjct: 385 EEGS---EAA--------ASTAVVIAGRSLNPNRVTFKA---------NRPFLVFIREVP 424

Query: 274 F 274
            
Sbjct: 425 L 425


>5E44-A nrPDB
          Length = 259

 Score = 35.9 bits (81), Expect = 0.028,   Method: Composition-based stats.
 Identities = 13/68 (19%), Positives = 27/68 (39%), Gaps = 2/68 (2%)

Query: 155 NLDPEQMSQVLDAMFEKL-VKEGEHVIDQGDDGDNFYVIDRGTFDIYV-KCDGVGRCVGN 212
            L+  ++ Q+ + +  K  +++G+ +   GD+    Y I  GT   Y     G  +    
Sbjct: 42  TLNDSELDQLDEIIERKKPIQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDEQITAF 101

Query: 213 YDNRGSFG 220
           +      G
Sbjct: 102 HLAGDLVG 109


>3E6B-A nrPDB
          Length = 250

 Score = 34.4 bits (77), Expect = 0.089,   Method: Composition-based stats.
 Identities = 16/108 (14%), Positives = 39/108 (36%), Gaps = 6/108 (5%)

Query: 171 KLVKEGEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALMYNTP 229
           +   +G  VI  G++  +   +  G   +  +  DG  + +         G+L   Y T 
Sbjct: 35  RDFAKGSAVIMPGEEITSMIFLVEGKIKLDIIFEDGSEKLLYYAGGNSLIGKL---YPTG 91

Query: 230 RAATITATSPG-ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLK 276
                TA  P    W     + R +   +     +++++++  + +  
Sbjct: 92  NNIYATAMEPTRTCW-FSEKSLRTVFRTDEDMIFEIFKNYLTKVAYYA 138


>4FHA-A nrPDB
          Length = 311

 Score = 33.2 bits (74), Expect = 0.21,   Method: Composition-based stats.
 Identities = 18/112 (16%), Positives = 41/112 (36%), Gaps = 9/112 (8%)

Query: 99  FNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
           +N P      +     A+A +      +   R++   T +   RL +          +  
Sbjct: 114 YNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD------HPNIIGV 167

Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVID---RGTFDIYVKCDGVG 207
           ++ + + +  +    K  E +I  G+DGD F+ ++    G   +    +G  
Sbjct: 168 KECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGDE 219


>1Z5V-A nrPDB
          Length = 474

 Score = 32.1 bits (71), Expect = 0.50,   Method: Composition-based stats.
 Identities = 24/152 (15%), Positives = 51/152 (33%), Gaps = 19/152 (12%)

Query: 276 KSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADS--FFI----VESGEVKITMKRKGKS 329
           +S+    +  V+DV+  ++      +++ G    +   +I    +  GEV  T   K   
Sbjct: 280 QSVASVRKTTVLDVMR-RLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQ 338

Query: 330 EVEENGAVEIARCFRGQYFGELALVTNKP------RAASAHAIGTVKCLAMDVQAFERLL 383
            + E                ++AL    P      R +           ++    FER  
Sbjct: 339 RIRERKLANFIPWGPASI--QVALSRKSPYLPSAHRVSGLMMANHTSISSL----FERTC 392

Query: 384 GPCMEIMKRNIATYEEQLVALFGTNMDIVEPT 415
               ++ KR     + +   +F  N D ++ +
Sbjct: 393 RQYDKLRKREAFLEQFRKEDMFKDNFDEMDTS 424


>1XKW-A nrPDB
          Length = 665

 Score = 32.1 bits (71), Expect = 0.52,   Method: Composition-based stats.
 Identities = 13/89 (14%), Positives = 28/89 (31%), Gaps = 3/89 (3%)

Query: 33  LQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEE 92
           + +    Q + +R+                    G +    +N +    R D EN  +E+
Sbjct: 440 VSYAEVYQPQADRQTWNSEPLSPVEGKTYETGIKGELADGRLNLSLAAFRIDLENNPQED 499

Query: 93  AAEAGAFNAPVINRFTRRASVCAEAYNPD 121
               G  N P    +     V ++ +  +
Sbjct: 500 PDHPGPPNNPF---YISGGKVRSQGFELE 525


>6CXO-A nrPDB
          Length = 529

 Score = 29.4 bits (64), Expect = 3.0,   Method: Composition-based stats.
 Identities = 21/121 (17%), Positives = 42/121 (34%), Gaps = 4/121 (3%)

Query: 201 VKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGAL-WGLDRVTFRRIIVKNNA 259
              D V     +Y+    FG L   Y T  + + +      + + LD+ + +   V  N 
Sbjct: 297 TFLDDVKALPTSYEKGEYFGFLE-TYGTHYSTSGSLGGQYEIVYVLDKASMKEKGVDLND 355

Query: 260 KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ--IIAQGDLADSFFIVESG 317
            K  +  +    +P    L+ +     V+  G    ++G+   I     + D    +  G
Sbjct: 356 VKHCLGFNMDLRIPLQDDLKDASVTASVNADGCIKTDNGKTVDITRDNIIDDVISFIRGG 415

Query: 318 E 318
            
Sbjct: 416 T 416


>5MMI-U nrPDB
          Length = 198

 Score = 29.0 bits (63), Expect = 4.4,   Method: Composition-based stats.
 Identities = 22/181 (12%), Positives = 52/181 (28%), Gaps = 9/181 (4%)

Query: 48  AARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRF 107
           ++ F     +   +  +    IP+K    +    +                 N P     
Sbjct: 12  SSSFAFSNPSSNVSATSFTFQIPNKKAQISCISSKKLHTQKSFNFHDAVTPMNKPSF-GR 70

Query: 108 TRRASVCAEAYNPDEEEDDAESRIIHPKT-----DDQRNRLQEACKDILLFKNLDPEQMS 162
               +   EA  P  EE          K        +   + +  +   +      + ++
Sbjct: 71  DLMVAQATEAVAPTTEEAATSQPKTSKKAKKLKYPRRILDVYQILQS-PIITEAAIKNIA 129

Query: 163 QVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGEL 222
                +F   V+  + +I   +   NF+ +     +  ++ DG  +     +   +  EL
Sbjct: 130 DENSLLFTVDVRADKKMIR--EAISNFFGVKVRKVNTLIRPDGTKKAYIMLNKEYNASEL 187

Query: 223 A 223
           A
Sbjct: 188 A 188


  Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
    Posted date:  Jan 3, 2023  9:05 PM
  Number of letters in database: 10,336,785
  Number of sequences in database:  36,641
  
Lambda     K      H
   0.304    0.122    0.293 

Lambda     K      H
   0.267   0.0376    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,393,741
Number of Sequences: 36641
Number of extensions: 491681
Number of successful extensions: 1838
Number of sequences better than 10.0: 70
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1416
Number of HSP's gapped (non-prelim): 210
length of query: 416
length of database: 10,336,785
effective HSP length: 100
effective length of query: 316
effective length of database: 6,672,685
effective search space: 2108568460
effective search space used: 2108568460
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 60 (27.8 bits)