BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P31324
(416 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
4X6Q-B nrPDB 858 0.0
1CX4-A nrPDB 625 e-179
3J4Q-B nrPDB 559 e-160
2QVS-B nrPDB 492 e-139
4DIN-B nrPDB 249 1e-66
6BYS-B nrPDB 235 3e-62
2QCS-B nrPDB 230 7e-61
5KBF-A nrPDB 197 8e-51
5J3U-A nrPDB 174 6e-44
4Z07-A nrPDB 125 4e-29
5FET-A nrPDB 122 4e-28
3SHR-A nrPDB 121 5e-28
5DYK-A nrPDB 117 8e-27
6FTF-B nrPDB 105 3e-23
6BQ8-A nrPDB 71 1e-12
5H78-A nrPDB 68 8e-12
4QX5-A nrPDB 66 3e-11
5JAX-A nrPDB 66 4e-11
5H77-A nrPDB 65 6e-11
5XBY-A nrPDB 63 3e-10
5V4S-A nrPDB 51 8e-07
6CJQ-A nrPDB 49 5e-06
4MGY-E nrPDB 46 3e-05
1O7F-A nrPDB 45 5e-05
4EV0-A nrPDB 45 6e-05
4F7Z-A nrPDB 45 7e-05
4AVC-A nrPDB 44 1e-04
3DKW-A nrPDB 42 4e-04
4CHV-A nrPDB 42 4e-04
5JON-A nrPDB 41 0.001
3I59-A nrPDB 39 0.003
5W5B-A nrPDB 39 0.004
4ORF-A nrPDB 39 0.004
5U6P-A nrPDB 39 0.004
4CYD-A nrPDB 37 0.022
2GAU-A nrPDB 36 0.039
3H3Z-A nrPDB 33 0.24
4I0B-A nrPDB 32 0.56
3KCC-A nrPDB 32 0.63
5H3O-A nrPDB 30 2.0
5I62-A nrPDB 29 3.1
1DK5-A nrPDB 29 3.9
>4X6Q-B nrPDB
Length = 416
Score = 858 bits (2218), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 415/416 (99%), Positives = 416/416 (100%)
Query: 1 MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD
Sbjct: 1 MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
Query: 61 AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120
AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP
Sbjct: 61 AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120
Query: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180
DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI
Sbjct: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180
Query: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPG 240
DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP+AATITATSPG
Sbjct: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPKAATITATSPG 240
Query: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300
ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ
Sbjct: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300
Query: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360
IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA
Sbjct: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360
Query: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416
ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Sbjct: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416
>1CX4-A nrPDB
Length = 305
Score = 625 bits (1611), Expect = e-179, Method: Compositional matrix adjust.
Identities = 300/305 (98%), Positives = 303/305 (99%)
Query: 112 SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 171
SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK
Sbjct: 1 SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 60
Query: 172 LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 231
LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA
Sbjct: 61 LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 120
Query: 232 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 291
ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG
Sbjct: 121 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 180
Query: 292 TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
TKVYNDGEQIIAQGD ADSFFIVESGEV+ITMKRKGKS++EENGAVEIARC RGQYFGEL
Sbjct: 181 TKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGEL 240
Query: 352 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 411
ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI
Sbjct: 241 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 300
Query: 412 VEPTA 416
VEPTA
Sbjct: 301 VEPTA 305
>3J4Q-B nrPDB
Length = 402
Score = 559 bits (1441), Expect = e-160, Method: Compositional matrix adjust.
Identities = 276/415 (66%), Positives = 329/415 (79%), Gaps = 21/415 (5%)
Query: 3 IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAG 62
I+IPAGLTELLQG+TVEVLR QP DL++FA+++FTRL+ E R+ + F T+
Sbjct: 4 IQIPAGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLR-EARRQESDTFIVSPTTFHTQE 62
Query: 63 AAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDE 122
++A I E+GE + +E PV ++FTRR SVCAE +NPDE
Sbjct: 63 SSAVPVI---------------EEDGESDSDSEDADLEVPVPSKFTRRVSVCAETFNPDE 107
Query: 123 EEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQ 182
EE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDAMFEK+VK EHVIDQ
Sbjct: 108 EEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQ 167
Query: 183 GDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGAL 242
GDDGDNFYVI+RGT+DI V D R VG YDNRGSFGELALMYNTPRAATI ATS G+L
Sbjct: 168 GDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSEGSL 227
Query: 243 WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQII 302
WGLDRVTFRRIIVKNNAKKRKM+ESFIES+P KSLE+SER+K+VDVIG K+Y DGE+II
Sbjct: 228 WGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERII 287
Query: 303 AQGDLADSFFIVESGEVKITMKRKGKSEVEENGA---VEIARCFRGQYFGELALVTNKPR 359
AQG+ ADSF+I+ESGEV I ++ K KS +NG VEIA C +GQYFGELALVTNKPR
Sbjct: 288 AQGEKADSFYIIESGEVSILIRSKTKS--NKNGGNQEVEIAHCHKGQYFGELALVTNKPR 345
Query: 360 AASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEP 414
AASA+A+G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +FG+N+D+++P
Sbjct: 346 AASAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLMDP 400
>2QVS-B nrPDB
Length = 310
Score = 492 bits (1267), Expect = e-139, Method: Compositional matrix adjust.
Identities = 234/310 (75%), Positives = 269/310 (86%), Gaps = 5/310 (1%)
Query: 108 TRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDA 167
TRR SVCAE +NPDEEE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDA
Sbjct: 1 TRRVSVCAETFNPDEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDA 60
Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYN 227
MFEK+VK EHVIDQGDDGDNFYVI+RGT+DI V D R VG YDNRGSFGELALMYN
Sbjct: 61 MFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYN 120
Query: 228 TPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVV 287
TPRAATI ATS G+LWGLDRVTFRRIIVKNNAKKRKM+ESFIES+P KSLE+SER+K+V
Sbjct: 121 TPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIV 180
Query: 288 DVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGA---VEIARCFR 344
DVIG K+Y DGE+IIAQG+ ADSF+I+ESGEV I ++ K KS +NG VEIA C +
Sbjct: 181 DVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKS--NKNGGNQEVEIAHCHK 238
Query: 345 GQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVAL 404
GQYFGELALVTNKPRAASA+ +G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +
Sbjct: 239 GQYFGELALVTNKPRAASAYGVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKM 298
Query: 405 FGTNMDIVEP 414
FG+N+D+++P
Sbjct: 299 FGSNLDLMDP 308
>4DIN-B nrPDB
Length = 381
Score = 249 bits (637), Expect = 1e-66, Method: Compositional matrix adjust.
Identities = 147/392 (37%), Positives = 210/392 (53%), Gaps = 46/392 (11%)
Query: 8 GLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGG 67
G+ ++L+ V + +P ++F +HF +L++E R+ AR
Sbjct: 26 GIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILAR----------------- 68
Query: 68 GIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA 127
+S+S++ +E N PV+ RR V AE Y E+DA
Sbjct: 69 -------------QKSNSQSDSHDEEVSPTPPN-PVVKARRRRGGVSAEVYT----EEDA 110
Query: 128 ES--RIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDD 185
S R + PK L +A +LF +LD + S + DAMF GE VI QG++
Sbjct: 111 VSYVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNE 170
Query: 186 GDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGL 245
GDNFYV+D+G D+YV G V N GSFGELAL+Y TPRAAT+ A + LWG+
Sbjct: 171 GDNFYVVDQGEVDVYVN----GEWVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGI 226
Query: 246 DRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQG 305
DR ++RRI++ + +KRKMYE F+ + L+SLE ERL V D + + DGE+I+ QG
Sbjct: 227 DRDSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQG 286
Query: 306 DLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA 365
+ D F+I+ G + +R E VE+ R YFGE+AL+ N+PRAA+ A
Sbjct: 287 EPGDDFYIITEGTASVLQRRSPNEEY-----VEVGRLGPSDYFGEIALLLNRPRAATVVA 341
Query: 366 IGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
G +KC+ +D FER+LGPC EI+KRNI Y
Sbjct: 342 RGPLKCVKLDRPRFERVLGPCSEILKRNIQRY 373
>6BYS-B nrPDB
Length = 379
Score = 235 bits (599), Expect = 3e-62, Method: Compositional matrix adjust.
Identities = 132/298 (44%), Positives = 181/298 (60%), Gaps = 15/298 (5%)
Query: 102 PVINRFTRRASVCAEAYNPDEEEDDAES--RIIHPKTDDQRNRLQEACKDILLFKNLDPE 159
PV+ RR ++ AE Y E+DA S R + PK L +A + +LF +LD
Sbjct: 87 PVVKGRRRRGAISAEVYT----EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDN 142
Query: 160 QMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSF 219
+ S + DAMF GE VI QGD+GDNFYVID+G D+YV + VG GSF
Sbjct: 143 ERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEW-ATSVGE---GGSF 198
Query: 220 GELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLE 279
GELAL+Y TPRAAT+ A + LWG+DR ++RRI++ + +KRKMYE F+ + L+SL+
Sbjct: 199 GELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD 258
Query: 280 VSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEI 339
ERL V D + + DG++I+ QG+ D FFI+ G + +R SE EE VE+
Sbjct: 259 KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRR---SENEE--FVEV 313
Query: 340 ARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
R YFGE+AL+ N+PRAA+ A G +KC+ +D FER+LGPC +I+KRNI Y
Sbjct: 314 GRLGPSDYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 371
>2QCS-B nrPDB
Length = 291
Score = 230 bits (587), Expect = 7e-61, Method: Compositional matrix adjust.
Identities = 127/289 (43%), Positives = 177/289 (61%), Gaps = 11/289 (3%)
Query: 109 RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAM 168
RR ++ AE Y EE+ + R + PK L +A + +LF +LD + S + DAM
Sbjct: 5 RRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAM 62
Query: 169 FEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNT 228
F GE VI QGD+GDNFYVID+G D+YV + VG GSFGELAL+Y T
Sbjct: 63 FPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEW-ATSVGE---GGSFGELALIYGT 118
Query: 229 PRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVD 288
PRAAT+ A + LWG+DR ++RRI++ + +KRKMYE F+ + L+SL+ ERL V D
Sbjct: 119 PRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVAD 178
Query: 289 VIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYF 348
+ + DG++I+ QG+ D FFI+ G + +R SE EE VE+ R YF
Sbjct: 179 ALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRR---SENEE--FVEVGRLGPSDYF 233
Query: 349 GELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
GE+AL+ N+P+AA+ A G +KC+ +D FER+LGPC +I+KRNI Y
Sbjct: 234 GEIALLMNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 282
>5KBF-A nrPDB
Length = 301
Score = 197 bits (501), Expect = 8e-51, Method: Compositional matrix adjust.
Identities = 113/297 (38%), Positives = 174/297 (58%), Gaps = 12/297 (4%)
Query: 109 RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAM 168
+R SV AEAY ++ D ++ K + ++ +++EA + LF +L+ ++ +++A
Sbjct: 6 KRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIVNAF 65
Query: 169 FEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELALMYN 227
F+K V++G ++I++GD GD YVID+G +IY K + + ++ FGELAL+YN
Sbjct: 66 FDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELALLYN 125
Query: 228 TPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVV 287
+ RAAT TA + LW LDR +F II AKKRKMYE + + LK ++ ER KV
Sbjct: 126 SKRAATATALTKCHLWALDRESFTYIIKDMVAKKRKMYEDILSHVNILKDMDPYERCKVA 185
Query: 288 DVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQY 347
D + +K YNDGE II +G+ D+FFI+ G + K I +G Y
Sbjct: 186 DCLKSKSYNDGEIIIKEGEEGDTFFILIDGNAVASKDNKV-----------IKTYTKGDY 234
Query: 348 FGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVAL 404
FGELAL+ NKPRAA+ A + + +D ++F+RLLGP +I+ RN+ Y++ L L
Sbjct: 235 FGELALLKNKPRAATIKAQNFCQVVYLDRKSFKRLLGPIEDILHRNVENYKKVLNEL 291
>5J3U-A nrPDB
Length = 261
Score = 174 bits (441), Expect = 6e-44, Method: Compositional matrix adjust.
Identities = 95/266 (35%), Positives = 151/266 (56%), Gaps = 5/266 (1%)
Query: 132 IHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYV 191
++ K + Q+ +L+ + LF +LD + ++ V+ AM EK ++ +I +GDDG+ Y+
Sbjct: 1 VYEKDEGQKEQLERILRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYI 60
Query: 192 IDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
+ G + DG R V +FGELAL+YN PRAAT+T+ S LW L R TF
Sbjct: 61 VQSGELNCSKLIDGEERVVKVVGPGDAFGELALLYNAPRAATVTSVSACDLWELGRDTFN 120
Query: 252 RIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSF 311
I+ K+R MY+SF++S+ L ++ ER KV D + T+++ DG I+ QG+L D F
Sbjct: 121 AIVKDAATKRRSMYDSFLKSVHILDGMDAYERGKVADALRTEMFTDGAYIVRQGELGDVF 180
Query: 312 FIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKC 371
+IVE G T KS +E+ + G YFGELAL+ +PRAA+ A G K
Sbjct: 181 YIVEEGSAVAT-----KSFGPGQPPIEVKKYQAGDYFGELALINEEPRAANVIAHGICKV 235
Query: 372 LAMDVQAFERLLGPCMEIMKRNIATY 397
++ ++F+RL+G +++ + + Y
Sbjct: 236 ACLERKSFKRLMGSVQDLLSKKASEY 261
Score = 58.5 bits (140), Expect = 5e-09, Method: Compositional matrix adjust.
Identities = 44/160 (27%), Positives = 79/160 (49%), Gaps = 11/160 (6%)
Query: 99 FNAPVINRFTRRASVCA-EAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLD 157
+NAP R A+V + A + E D + I+ +R+ K + + +D
Sbjct: 95 YNAP------RAATVTSVSACDLWELGRDTFNAIVKDAATKRRSMYDSFLKSVHILDGMD 148
Query: 158 PEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRC---VGNYD 214
+ +V DA+ ++ +G +++ QG+ GD FY+++ G+ + K G G+ V Y
Sbjct: 149 AYERGKVADALRTEMFTDGAYIVRQGELGDVFYIVEEGS-AVATKSFGPGQPPIEVKKYQ 207
Query: 215 NRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
FGELAL+ PRAA + A + L+R +F+R++
Sbjct: 208 AGDYFGELALINEEPRAANVIAHGICKVACLERKSFKRLM 247
>4Z07-A nrPDB
Length = 262
Score = 125 bits (314), Expect = 4e-29, Method: Compositional matrix adjust.
Identities = 79/252 (31%), Positives = 126/252 (50%), Gaps = 9/252 (3%)
Query: 133 HPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVI 192
+PK+ ++ ++EA D KNL+ Q+ +++D M+ + +I +GD G YV+
Sbjct: 10 YPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 69
Query: 193 DRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
+ G + V +GV C FGELA++YN R AT+ LW +DR F+
Sbjct: 70 EDGKVE--VTKEGVKLCTMGPGK--VFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 125
Query: 253 IIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFF 312
I+++ K Y F++S+P +SL K+ DV+ Y +GE II QG D+FF
Sbjct: 126 IMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFF 185
Query: 313 IVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCL 372
I+ G V +T + + V + +G +FGE AL R A+ A V CL
Sbjct: 186 IISKGTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCL 240
Query: 373 AMDVQAFERLLG 384
+D +F+ L+G
Sbjct: 241 VIDRDSFKHLIG 252
>5FET-A nrPDB
Length = 847
Score = 122 bits (305), Expect = 4e-28, Method: Compositional matrix adjust.
Identities = 78/263 (29%), Positives = 135/263 (51%), Gaps = 15/263 (5%)
Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
++ + K+ L+ L+ ++ + + M + K G+ VI QG+ G F++I+ G FD+YV
Sbjct: 43 IKASLKNNLVCSTLNDNEILTLSNYMQFFVFKGGDLVIKQGEKGSYFFIINSGKFDVYVN 102
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKR 262
+ V + SFGE AL++NT R+ATI A + G LWG+ R TFR + + + +
Sbjct: 103 ----DKKVKSMGKGSSFGEAALIHNTQRSATIMAETDGTLWGVQRSTFRATLKQLSNRNF 158
Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
SFI+S+ L +++ + + +++ GE I+ QGD D FI++ G+ +
Sbjct: 159 NENRSFIDSVSVFDMLTEAQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKEGKATVF 218
Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERL 382
+ K EI +G YFGE AL+ ++PR+A+ A C ++ + +
Sbjct: 219 INDK-----------EIRVLNKGSYFGERALLYDEPRSATIIAKEPTACASICRKLLNIV 267
Query: 383 LGPCMEIMKRNIATYEEQLVALF 405
LG ++ RNI T Q +F
Sbjct: 268 LGNLQVVLFRNIMTEALQQSEIF 290
Score = 56.6 bits (135), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 34/116 (29%), Positives = 61/116 (52%), Gaps = 5/116 (4%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI 199
N + K + +F+ L +Q + +++A +EG+++I +G+ G FY+I G ++
Sbjct: 400 HNNKKSIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEV 459
Query: 200 YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGA-LWGLDRVTFRRII 254
K R +G D FGE AL+Y+ PR A+I + + W +D+ F +II
Sbjct: 460 -TKNGKRLRTLGKND---YFGERALLYDEPRTASIISKATSVECWFVDKSVFLQII 511
Score = 55.8 bits (133), Expect = 3e-08, Method: Compositional matrix adjust.
Identities = 55/266 (20%), Positives = 118/266 (44%), Gaps = 30/266 (11%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGD-DGDNFYVIDRGTFD 198
RN + EA + +F+ EQ++ + D + H++ + + ++ G +
Sbjct: 277 RNIMTEALQQSEIFRQFSAEQLNDLADTAIVRDYPANYHILHKDKVKSVKYLIVLEGKVE 336
Query: 199 IYVKCDGVG-----RCVGN---YDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTF 250
+++ + +G + G+ + + F + + A IT + G + +
Sbjct: 337 LFLDDESIGILTRGKSFGDQYVLNQKQKFRHTVKSLDVCKIALITESCLADCLGDNNIDA 396
Query: 251 RRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADS 310
+ +N KK S I+ + + L + +++ T Y +G+ II +G++
Sbjct: 397 S---IDHNNKK-----SIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSR 448
Query: 311 FFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-V 369
F+I+++GEV++T K + +N YFGE AL+ ++PR AS + T V
Sbjct: 449 FYIIKNGEVEVTKNGKRLRTLGKN-----------DYFGERALLYDEPRTASIISKATSV 497
Query: 370 KCLAMDVQAFERLL-GPCMEIMKRNI 394
+C +D F +++ GP + ++ I
Sbjct: 498 ECWFVDKSVFLQIIQGPMLTHLEERI 523
>3SHR-A nrPDB
Length = 299
Score = 121 bits (304), Expect = 5e-28, Method: Compositional matrix adjust.
Identities = 78/250 (31%), Positives = 126/250 (50%), Gaps = 9/250 (3%)
Query: 135 KTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDR 194
K++ ++ ++EA D KNL+ Q+ +++D M+ + +I +GD G YV++
Sbjct: 29 KSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVMED 88
Query: 195 GTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
G + V +GV C FGELA++YN R AT+ LW +DR F+ I+
Sbjct: 89 GKVE--VTKEGVKLCTMGPGK--VFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQTIM 144
Query: 255 VKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIV 314
++ K Y F++S+P +SL K+ DV+ Y +GE II QG D+FFI+
Sbjct: 145 MRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFII 204
Query: 315 ESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAM 374
G+V +T + + V + +G +FGE AL R A+ A V CL +
Sbjct: 205 SKGKVNVT-----REDSPNEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVI 259
Query: 375 DVQAFERLLG 384
D +F+ L+G
Sbjct: 260 DRDSFKHLIG 269
Score = 47.0 bits (110), Expect = 2e-05, Method: Compositional matrix adjust.
Identities = 37/134 (27%), Positives = 61/134 (45%), Gaps = 10/134 (7%)
Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
+ E K + F++L E +S++ D + E + GE++I QG GD F++I +G +
Sbjct: 151 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGKVN 210
Query: 199 IYVKCDGVG------RCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
+ + D R +G D FGE AL R A + A +DR +F+
Sbjct: 211 V-TREDSPNEDPVFLRTLGKGD---WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKH 266
Query: 253 IIVKNNAKKRKMYE 266
+I + K YE
Sbjct: 267 LIGGLDDVSNKAYE 280
>5DYK-A nrPDB
Length = 853
Score = 117 bits (293), Expect = 8e-27, Method: Compositional matrix adjust.
Identities = 80/282 (28%), Positives = 139/282 (49%), Gaps = 18/282 (6%)
Query: 124 EDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQG 183
ED E R K + + ++ + K+ L+ L+ ++ + + M + K G VI QG
Sbjct: 33 EDHLELR---EKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNYMQFFVFKSGNLVIKQG 89
Query: 184 DDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALW 243
+ G F++I+ G FD+YV + V SFGE AL++NT R+ATI A + G LW
Sbjct: 90 EKGSYFFIINSGKFDVYVN----DKKVKTMGKGSSFGEAALIHNTQRSATIIAETDGTLW 145
Query: 244 GLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIA 303
G+ R TFR + + + + +FI+S+ L +++ + + + + GE I+
Sbjct: 146 GVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVK 205
Query: 304 QGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA 363
QGD D +I++ G+ + + + EI +G YFGE AL+ ++PR+A+
Sbjct: 206 QGDYGDVLYILKEGKATVYINDE-----------EIRVLEKGSYFGERALLYDEPRSATI 254
Query: 364 HAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALF 405
A C ++ + +LG ++ RNI T Q +F
Sbjct: 255 IAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIF 296
Score = 57.0 bits (136), Expect = 2e-08, Method: Compositional matrix adjust.
Identities = 52/169 (30%), Positives = 82/169 (48%), Gaps = 29/169 (17%)
Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY 200
N + K + +F+ L +Q + +++A +EG+++I +G+ G FY+I G +I
Sbjct: 407 NNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEI- 465
Query: 201 VKCDGVGRCVGNYDNRGSFGELALMYNTPRAAT-ITATSPGALWGLDRVTFRRIIVKNNA 259
VK R +G D FGE AL+Y+ PR A+ I+ + W +D+ F +II
Sbjct: 466 VKNKKRLRTLGKND---YFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQII----- 517
Query: 260 KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYND---GEQIIAQG 305
P L LE ER+K+ D TKV D E+II +G
Sbjct: 518 -----------QGPMLAHLE--ERIKMQD---TKVEMDELETERIIGRG 550
Score = 54.7 bits (130), Expect = 7e-08, Method: Compositional matrix adjust.
Identities = 58/263 (22%), Positives = 115/263 (43%), Gaps = 24/263 (9%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVID-RGTFD 198
RN + EA + +FK +Q++ + D + +++ + Y+I G +
Sbjct: 283 RNIMTEALQQSEIFKQFSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVE 342
Query: 199 IYVKCDGVGRCVGNYDNRG-SFG-ELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
+++ +G +RG SFG + L P TI + + + +
Sbjct: 343 LFLDDTSIGIL-----SRGMSFGDQYVLNQKQPFKHTIKSLEVCKIALITETCLADCLGN 397
Query: 257 NNAKKRKMY---ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFI 313
NN Y +S I+ + + L + +++ T Y +G+ II +G++ F+I
Sbjct: 398 NNIDASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYI 457
Query: 314 VESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA-HAIGTVKCL 372
+++GEV+I +K + +N YFGE AL+ ++PR AS + V+C
Sbjct: 458 IKNGEVEIVKNKKRLRTLGKN-----------DYFGERALLYDEPRTASVISKVNNVECW 506
Query: 373 AMDVQAFERLL-GPCMEIMKRNI 394
+D F +++ GP + ++ I
Sbjct: 507 FVDKSVFLQIIQGPMLAHLEERI 529
>6FTF-B nrPDB
Length = 304
Score = 105 bits (263), Expect = 3e-23, Method: Compositional matrix adjust.
Identities = 77/293 (26%), Positives = 140/293 (47%), Gaps = 28/293 (9%)
Query: 109 RRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAM 168
RR +V +E +P E+ K++D+ N + + +LF L+ + + V AM
Sbjct: 4 RRRTVRSEGIDP--EKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVAGAM 61
Query: 169 FEKLVKEGEHVIDQGDDGDN-FYVIDRGTFDI-------YVKCDGVGRCVGNYDNRGSFG 220
K + +++ G N Y+I G DI Y+K +G + G
Sbjct: 62 QRATFKHDDCIMEAGQTTCNKLYIIQSGHADIIKEGQKVYLKTEGT-----------AVG 110
Query: 221 ELALMYNTPRAATITATSPGAL-WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLE 279
EL LMY+TP AT+ + + W LDR T+R +++ ++R+ Y F+ ++PFL L+
Sbjct: 111 ELELMYDTPVVATVKVCTDELIAWVLDRDTYRNLVMGTAIRRRETYIQFLANVPFLGGLD 170
Query: 280 VSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEI 339
E+L++ D + ++ ++ GE II G+ + +I+ G V++ + R E ++
Sbjct: 171 SYEKLQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEV-IGRDADGE-----PTKV 224
Query: 340 ARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKR 392
+G + GEL + N A A V ++ + FE LGP ++++KR
Sbjct: 225 CEFTQGDHIGELEFLNNHRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKR 277
>6BQ8-A nrPDB
Length = 152
Score = 70.9 bits (172), Expect = 1e-12, Method: Compositional matrix adjust.
Identities = 40/130 (30%), Positives = 73/130 (56%), Gaps = 6/130 (4%)
Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
+ Y +F+ S+ LK+L + K++D + + Y+ G+ II +G+ +FFI+ G+VK+T
Sbjct: 9 EQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 68
Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLAMDVQAFER 381
+G + + I +G+YFGE AL+++ R+A+ A V CL +D + F +
Sbjct: 69 QSTEGHDQPQ-----LIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQ 123
Query: 382 LLGPCMEIMK 391
+G E+ K
Sbjct: 124 TVGTFEELQK 133
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 26/110 (23%), Positives = 58/110 (52%), Gaps = 3/110 (2%)
Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVG 207
+ + L KNL +++++++D + + +G+++I +G++G F+++ +G + +G
Sbjct: 16 RSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVTQSTEGHD 75
Query: 208 --RCVGNYDNRGSFGELALMYNTPRAATITATSPG-ALWGLDRVTFRRII 254
+ + FGE AL+ + R+A I A A +DR TF + +
Sbjct: 76 QPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTV 125
>5H78-A nrPDB
Length = 197
Score = 67.8 bits (164), Expect = 8e-12, Method: Compositional matrix adjust.
Identities = 29/58 (50%), Positives = 41/58 (70%)
Query: 3 IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
++IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+ E + + + + D
Sbjct: 4 MQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRSERVNERVKQLAEKAKEATD 61
>4QX5-A nrPDB
Length = 153
Score = 65.9 bits (159), Expect = 3e-11, Method: Compositional matrix adjust.
Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
K Y F++S+P +SL K+ DV+ Y +GE II QG D+FFI+ G V
Sbjct: 7 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66
Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE 380
+T + + V + +G +FGE AL R A+ A V CL +D +F+
Sbjct: 67 VT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFK 121
Query: 381 RLLG 384
L+G
Sbjct: 122 HLIG 125
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 38/134 (28%), Positives = 62/134 (46%), Gaps = 10/134 (7%)
Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
+ E K + F++L E +S++ D + E + GE++I QG GD F++I +GT +
Sbjct: 7 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66
Query: 199 IYVKCDGVG------RCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
+ + D R +G D FGE AL R A + A +DR +F+
Sbjct: 67 V-TREDSPSEDPVFLRTLGKGD---WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKH 122
Query: 253 IIVKNNAKKRKMYE 266
+I + K YE
Sbjct: 123 LIGGLDDVSNKAYE 136
>5JAX-A nrPDB
Length = 135
Score = 65.9 bits (159), Expect = 4e-11, Method: Compositional matrix adjust.
Identities = 41/124 (33%), Positives = 61/124 (49%), Gaps = 5/124 (4%)
Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
K Y F++S+P +SL K+ DV+ Y +GE II QG D+FFI+ G V
Sbjct: 7 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66
Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE 380
+T + + V + +G +FGE AL R A+ A V CL +D +F+
Sbjct: 67 VT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFK 121
Query: 381 RLLG 384
L+G
Sbjct: 122 HLIG 125
Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust.
Identities = 35/122 (28%), Positives = 58/122 (47%), Gaps = 10/122 (8%)
Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
+ E K + F++L E +S++ D + E + GE++I QG GD F++I +GT +
Sbjct: 7 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66
Query: 199 IYVKCDGVG------RCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
+ + D R +G D FGE AL R A + A +DR +F+
Sbjct: 67 V-TREDSPSEDPVFLRTLGKGD---WFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKH 122
Query: 253 II 254
+I
Sbjct: 123 LI 124
>5H77-A nrPDB
Length = 90
Score = 65.1 bits (157), Expect = 6e-11, Method: Composition-based stats.
Identities = 28/39 (71%), Positives = 36/39 (92%)
Query: 4 EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQE 42
+IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+Q+
Sbjct: 5 QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRQQ 43
>5XBY-A nrPDB
Length = 97
Score = 62.8 bits (151), Expect = 3e-10, Method: Composition-based stats.
Identities = 28/48 (58%), Positives = 38/48 (79%)
Query: 4 EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARF 51
+IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL++ ++ F
Sbjct: 5 QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARNKEQQNAF 52
>5V4S-A nrPDB
Length = 465
Score = 51.2 bits (121), Expect = 8e-07, Method: Compositional matrix adjust.
Identities = 31/123 (25%), Positives = 60/123 (48%), Gaps = 9/123 (7%)
Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
K +++ +E +PFLK + + +V + ++ +G+ I +G+ D +I+ G V
Sbjct: 332 KIQLHRDLLEKVPFLKGADPALVTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVD 391
Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE 380
I ++ + + GQ+FGELALV + PR+A+ A T + + F+
Sbjct: 392 I---------LDSDEKTILLSLQEGQFFGELALVMDAPRSATVRATTTCEIYTLSKTDFD 442
Query: 381 RLL 383
+L
Sbjct: 443 NVL 445
Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust.
Identities = 34/120 (28%), Positives = 60/120 (50%), Gaps = 9/120 (7%)
Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVG 211
K DP ++ ++ +M + EG+ + +G+ GD+ Y++ G+ DI D + +
Sbjct: 345 FLKGADPALVTSLVFSMKPMIFLEGDTIFRRGEKGDDLYILSEGSVDI---LDSDEKTIL 401
Query: 212 NYDNRGS-FGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIE 270
G FGELAL+ + PR+AT+ AT+ ++ L + F N K+ + S IE
Sbjct: 402 LSLQEGQFFGELALVMDAPRSATVRATTTCEIYTLSKTDF-----DNVLKRFSQFRSAIE 456
>6CJQ-A nrPDB
Length = 456
Score = 48.5 bits (114), Expect = 5e-06, Method: Compositional matrix adjust.
Identities = 37/132 (28%), Positives = 66/132 (50%), Gaps = 11/132 (8%)
Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
+ + + LFK E + ++ + + GE++I G+ G + Y I+RG+ ++ + D
Sbjct: 313 DVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGSVEV-LSAD 371
Query: 205 GVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII---------V 255
R + + FGE+AL+ PR AT+ A + L+ LD+ TF RI+ +
Sbjct: 372 EKTRYAILSEGQ-FFGEMALILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEIAAQI 430
Query: 256 KNNAKKRKMYES 267
+ A +RK ES
Sbjct: 431 QELAVRRKELES 442
Score = 45.8 bits (107), Expect = 4e-05, Method: Compositional matrix adjust.
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 9/96 (9%)
Query: 294 VYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELAL 353
+Y GE II G++ + + G V++ + + A GQ+FGE+AL
Sbjct: 340 IYGPGEYIIRAGEMGSDVYFINRGSVEV---------LSADEKTRYAILSEGQFFGEMAL 390
Query: 354 VTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEI 389
+ PR A+ A +D + F+R+L EI
Sbjct: 391 ILRAPRTATVRARAFCDLYRLDKETFDRILSRYPEI 426
>4MGY-E nrPDB
Length = 694
Score = 45.8 bits (107), Expect = 3e-05, Method: Compositional matrix adjust.
Identities = 40/138 (28%), Positives = 70/138 (50%), Gaps = 14/138 (10%)
Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
DA R+I K QR + L+ ++L K L +++ VL +FE K G
Sbjct: 8 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 65
Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
+ +QG++G ++Y+I +G+ ++ + GV + D+ FG+LAL+ + PRAA+I
Sbjct: 66 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGQLALVNDAPRAASIVLR 122
Query: 238 SPGA-LWGLDRVTFRRII 254
+D+ F RI+
Sbjct: 123 EDNCHFLRVDKEDFNRIL 140
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 20/95 (21%)
Query: 291 GTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGE 350
GT ++N GE+ S++I+ G V + + KG + G FG+
Sbjct: 64 GTVLFNQGEE-------GTSWYIILKGSVNVVIYGKGV----------VCTLHEGDDFGQ 106
Query: 351 LALVTNKPRAASAHAIGTVKC--LAMDVQAFERLL 383
LALV + PRAAS + C L +D + F R+L
Sbjct: 107 LALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 140
>1O7F-A nrPDB
Length = 469
Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust.
Identities = 42/150 (28%), Positives = 74/150 (49%), Gaps = 14/150 (9%)
Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
DA R+I K QR + L+ ++L K L +++ VL +FE K G
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370
Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
+ +QG++G ++Y+I +G+ ++ + GV + D+ FG+LAL+ + PRAA+I
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIVLR 427
Query: 238 SPGA-LWGLDRVTFRRIIVKNNAKKRKMYE 266
+D+ F RI+ A ++ E
Sbjct: 428 EDNCHFLRVDKEDFNRILRDVEANTVRLKE 457
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 29/109 (26%), Positives = 51/109 (46%), Gaps = 8/109 (7%)
Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV-----K 202
K + F+ P + Q+ + + +++G + QGD G N+Y + G+ D+ V
Sbjct: 45 KGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSH 104
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
D V C +FGE +++ NTPR ATI L +++ F+
Sbjct: 105 QDAVTICTLGIGT--AFGE-SILDNTPRHATIVTRESSELLRIEQEDFK 150
Score = 36.6 bits (83), Expect = 0.019, Method: Compositional matrix adjust.
Identities = 29/95 (30%), Positives = 44/95 (46%), Gaps = 20/95 (21%)
Query: 291 GTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGE 350
GT ++N GE+ S++I+ G V + + KG + G FG+
Sbjct: 369 GTVLFNQGEE-------GTSWYIILKGSVNVVIYGKGV----------VCTLHEGDDFGK 411
Query: 351 LALVTNKPRAASAHAIGTVKC--LAMDVQAFERLL 383
LALV + PRAAS + C L +D + F R+L
Sbjct: 412 LALVNDAPRAASI-VLREDNCHFLRVDKEDFNRIL 445
>4EV0-A nrPDB
Length = 216
Score = 45.1 bits (105), Expect = 6e-05, Method: Compositional matrix adjust.
Identities = 26/82 (31%), Positives = 44/82 (53%), Gaps = 6/82 (7%)
Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
++Y G+ I QGDL + ++V SG+V++ G E +A G+ FGE++
Sbjct: 25 RLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQE------RTLALLGPGELFGEMS 78
Query: 353 LVTNKPRAASAHAIGTVKCLAM 374
L+ R+ASA A+ + LA+
Sbjct: 79 LLDEGERSASAVAVEDTELLAL 100
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 27/104 (25%), Positives = 45/104 (43%), Gaps = 1/104 (0%)
Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCV 210
LF L PE++ L +L +G+ + QGD G Y++ G ++ G R +
Sbjct: 6 LFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQERTL 65
Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
FGE++L+ R+A+ A L L R + +I
Sbjct: 66 ALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALI 109
>4F7Z-A nrPDB
Length = 999
Score = 44.7 bits (104), Expect = 7e-05, Method: Compositional matrix adjust.
Identities = 36/118 (30%), Positives = 63/118 (53%), Gaps = 13/118 (11%)
Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
DA R+I K QR + L+ ++L K L +++ VL +FE K G
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370
Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATIT 235
+ +QG++G ++Y+I +G+ ++ + GV + D+ FG+LAL+ + PRAA+I
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIV 425
Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 29/111 (26%), Positives = 52/111 (46%), Gaps = 8/111 (7%)
Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV-----K 202
K + F+ P + Q+ + + +++G + QGD G N+Y + G+ D+ V
Sbjct: 45 KGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSH 104
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRI 253
D V C +FGE +++ NTPR ATI L +++ F+ +
Sbjct: 105 QDAVTICTLGIGT--AFGE-SILDNTPRHATIVTRESSELLRIEQEDFKAL 152
Score = 35.4 bits (80), Expect = 0.047, Method: Compositional matrix adjust.
Identities = 23/72 (31%), Positives = 34/72 (47%), Gaps = 17/72 (23%)
Query: 291 GTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGE 350
GT ++N GE+ S++I+ G V + + KG + G FG+
Sbjct: 369 GTVLFNQGEE-------GTSWYIILKGSVNVVIYGKGV----------VCTLHEGDDFGK 411
Query: 351 LALVTNKPRAAS 362
LALV + PRAAS
Sbjct: 412 LALVNDAPRAAS 423
>4AVC-A nrPDB
Length = 333
Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust.
Identities = 23/69 (33%), Positives = 38/69 (55%), Gaps = 7/69 (10%)
Query: 298 GEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNK 357
G+ ++ QG+ A SF ++ SG ++ S V ++G IAR G GE+AL+ +
Sbjct: 44 GQVLLRQGEPAVSFLLISSGSAEV-------SHVGDDGVAIIARALPGMIVGEIALLRDS 96
Query: 358 PRAASAHAI 366
PR+A+ I
Sbjct: 97 PRSATVTTI 105
Score = 37.4 bits (85), Expect = 0.012, Method: Compositional matrix adjust.
Identities = 26/105 (24%), Positives = 50/105 (47%), Gaps = 8/105 (7%)
Query: 176 GEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATI 234
G+ ++ QG+ +F +I G+ ++ +V DGV + GE+AL+ ++PR+AT+
Sbjct: 44 GQVLLRQGEPAVSFLLISSGSAEVSHVGDDGVA-IIARALPGMIVGEIALLRDSPRSATV 102
Query: 235 TATSPGALWGLDRVTFRRIIVKNNAKKRKM------YESFIESLP 273
T P W R F ++ +R + +F+ +P
Sbjct: 103 TTIEPLTGWTGGRGAFATMVHIPGVGERLLRTARQRLAAFVSPIP 147
>3DKW-A nrPDB
Length = 227
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VK 202
Q+ + LF+ L P Q+ ++L + + +G +V QG+ FY + G IY +
Sbjct: 8 QQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLT 67
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKNN 258
+G + + + R +F E + +TP AT A P L+ + R + N
Sbjct: 68 PEGQEKILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLRQLQDNT 124
>4CHV-A nrPDB
Length = 361
Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust.
Identities = 31/122 (25%), Positives = 53/122 (43%), Gaps = 13/122 (10%)
Query: 268 FIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKG 327
+ ++P + L + +++V + + G I G+ D F V G V
Sbjct: 229 LVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSV-------- 280
Query: 328 KSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCM 387
V VE+ G +FGE+AL++ +PR+A+ A TV L++ F+ L
Sbjct: 281 --SVATPNPVELGP---GAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQMLCSSSP 335
Query: 388 EI 389
EI
Sbjct: 336 EI 337
Score = 41.6 bits (96), Expect = 6e-04, Method: Compositional matrix adjust.
Identities = 29/119 (24%), Positives = 56/119 (47%), Gaps = 8/119 (6%)
Query: 135 KTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDR 194
+ D RN + + LF+ L P + +++ A+ + V G + G+ GD + +
Sbjct: 220 RGDFVRN--WQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVE 277
Query: 195 GTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRI 253
G+ + + V G + FGE+AL+ PR+AT++A + +L L F+ +
Sbjct: 278 GSVSVATP-NPVELGPGAF-----FGEMALISGEPRSATVSAATTVSLLSLHSADFQML 330
>5JON-A nrPDB
Length = 517
Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust.
Identities = 31/134 (23%), Positives = 57/134 (42%), Gaps = 17/134 (12%)
Query: 250 FRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLAD 309
R IV N +K + S+P + + + ++ + +V+ G+ II +G +
Sbjct: 376 LREEIVNFNCRK------LVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGK 429
Query: 310 SFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTV 369
+ ++ G V + K G E+ + G YFGE+ L+T R AS A
Sbjct: 430 KMYFIQHGVVSVLTK--GNKEM---------KLSDGSYFGEICLLTRGRRTASVRADTYC 478
Query: 370 KCLAMDVQAFERLL 383
+ ++ V F +L
Sbjct: 479 RLYSLSVDNFNEVL 492
Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 26/104 (25%), Positives = 49/104 (47%), Gaps = 6/104 (5%)
Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCV- 210
LF N DP ++ +L + ++ + G+++I +G G Y I G + K + +
Sbjct: 394 LFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMKLSD 453
Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
G+Y FGE+ L+ R A++ A + L+ L F ++
Sbjct: 454 GSY-----FGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVL 492
>3I59-A nrPDB
Length = 249
Score = 39.3 bits (90), Expect = 0.003, Method: Compositional matrix adjust.
Identities = 30/110 (27%), Positives = 52/110 (47%), Gaps = 12/110 (10%)
Query: 280 VSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEI 339
++++L+ VD + G + A+G+ D +I+ SG+VKI + + EN +
Sbjct: 47 LTKQLQPVD------FPRGHTVFAEGEPGDRLYIIISGKVKIGRR---APDGRENLLTIM 97
Query: 340 ARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEI 389
FGEL++ PR +SA I V+ ++MD A + EI
Sbjct: 98 GPS---DMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIADRPEI 144
Score = 33.9 bits (76), Expect = 0.14, Method: Compositional matrix adjust.
Identities = 24/104 (23%), Positives = 43/104 (41%), Gaps = 1/104 (0%)
Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC-DGVGRCV 210
+F+ ++P ++ + + G V +G+ GD Y+I G I + DG +
Sbjct: 35 IFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRAPDGRENLL 94
Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
FGEL++ PR ++ T + +DR R I
Sbjct: 95 TIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWI 138
>5W5B-A nrPDB
Length = 236
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/119 (21%), Positives = 53/119 (44%), Gaps = 13/119 (10%)
Query: 286 VVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM---KRKGKSEVEENGAVEIARC 342
+ + + K + G + AD +IV G +++ + +R+ + G V+
Sbjct: 45 LAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAVVNILHPGDVD---- 100
Query: 343 FRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
G++ L+ P + A+ CL +D QAFERLL I +R +++ +++
Sbjct: 101 ------GDIPLLLEMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSVAQRV 153
>4ORF-A nrPDB
Length = 340
Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/86 (30%), Positives = 42/86 (48%), Gaps = 7/86 (8%)
Query: 298 GEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNK 357
G+ +I QGD A +F ++ESG V++ S +G + G GE+AL+ +
Sbjct: 48 GQVLIRQGDPALTFMLIESGRVQV-------SHAVADGPPIVLDIEPGLIIGEIALLRDA 100
Query: 358 PRAASAHAIGTVKCLAMDVQAFERLL 383
P+ A+ A V D AF+ +L
Sbjct: 101 PKTATVVAAEPVIGWVGDRDAFDTIL 126
Score = 37.4 bits (85), Expect = 0.011, Method: Compositional matrix adjust.
Identities = 25/82 (30%), Positives = 40/82 (48%), Gaps = 2/82 (2%)
Query: 174 KEGEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALMYNTPRAA 232
+ G+ +I QGD F +I+ G + + DG V + + GE+AL+ + P+ A
Sbjct: 46 EPGQVLIRQGDPALTFMLIESGRVQVSHAVADG-PPIVLDIEPGLIIGEIALLRDAPKTA 104
Query: 233 TITATSPGALWGLDRVTFRRII 254
T+ A P W DR F I+
Sbjct: 105 TVVAAEPVIGWVGDRDAFDTIL 126
>5U6P-A nrPDB
Length = 660
Score = 38.9 bits (89), Expect = 0.004, Method: Compositional matrix adjust.
Identities = 26/104 (25%), Positives = 48/104 (46%), Gaps = 6/104 (5%)
Query: 152 LFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCV- 210
LF N DP ++ +L + ++ + G+++I +G G Y I G + K +
Sbjct: 475 LFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKSSKEMKLTD 534
Query: 211 GNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
G+Y FGE+ L+ R A++ A + L+ L F ++
Sbjct: 535 GSY-----FGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVL 573
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 27/134 (20%), Positives = 56/134 (41%), Gaps = 17/134 (12%)
Query: 250 FRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLAD 309
R IV N +K + ++P + + + ++ + +V+ G+ II +G +
Sbjct: 457 LREEIVNFNCRK------LVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGK 510
Query: 310 SFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTV 369
+ ++ G + K + ++ + G YFGE+ L+T R AS A
Sbjct: 511 KMYFIQHGVAGVITKSSKEMKLTD-----------GSYFGEICLLTKGRRTASVRADTYC 559
Query: 370 KCLAMDVQAFERLL 383
+ ++ V F +L
Sbjct: 560 RLYSLSVDNFNEVL 573
>4CYD-A nrPDB
Length = 225
Score = 36.6 bits (83), Expect = 0.022, Method: Compositional matrix adjust.
Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 1/92 (1%)
Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
+QE +F+ +DP ++ ++ M G + D+G+ GD Y+I G +
Sbjct: 2 VQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARH 61
Query: 203 C-DGVGRCVGNYDNRGSFGELALMYNTPRAAT 233
DG + FGEL++ PR ++
Sbjct: 62 APDGRENLLTIMGPSDMFGELSIFDPGPRTSS 93
Score = 29.6 bits (65), Expect = 2.6, Method: Compositional matrix adjust.
Identities = 21/81 (25%), Positives = 36/81 (44%), Gaps = 6/81 (7%)
Query: 295 YNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALV 354
+ G I +G+ D +I+ SG+VK+ + + EN + FGEL++
Sbjct: 32 FPRGATIFDEGEPGDRLYIITSGKVKLA---RHAPDGRENLLTIMGPS---DMFGELSIF 85
Query: 355 TNKPRAASAHAIGTVKCLAMD 375
PR +SA + V M+
Sbjct: 86 DPGPRTSSAVCVTEVHAATMN 106
>2GAU-A nrPDB
Length = 232
Score = 35.8 bits (81), Expect = 0.039, Method: Compositional matrix adjust.
Identities = 25/84 (29%), Positives = 45/84 (53%), Gaps = 8/84 (9%)
Query: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR-GQYFGELALVTNKPR 359
+ ++GD+ ++ F + G++KI R+G G I+R + GQ+FG +
Sbjct: 44 VFSEGDIPNNLFYLYEGKIKIL--REGVY-----GRFHISRIVKPGQFFGMRPYFAEETC 96
Query: 360 AASAHAIGTVKCLAMDVQAFERLL 383
+++A A+ K LA+ V+A E LL
Sbjct: 97 SSTAIAVENSKVLAIPVEAIEALL 120
>3H3Z-A nrPDB
Length = 235
Score = 33.1 bits (74), Expect = 0.24, Method: Compositional matrix adjust.
Identities = 27/105 (25%), Positives = 45/105 (42%), Gaps = 8/105 (7%)
Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCF-RGQYFGEL 351
+ Y+ GE + Q + A + +V G VK+ + G+ + F RG+ FGE
Sbjct: 35 RSYDRGETLFLQEEKAQAIHVVIDGWVKLF-------RMTPTGSEAVVSVFTRGESFGEA 87
Query: 352 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIAT 396
+ N P SA A+ + + + F L+ EI +AT
Sbjct: 88 VALRNTPYPVSAEAVTPCEVMHIPSPVFVSLMRRDPEICISILAT 132
Score = 31.6 bits (70), Expect = 0.68, Method: Compositional matrix adjust.
Identities = 21/93 (22%), Positives = 39/93 (41%), Gaps = 1/93 (1%)
Query: 148 KDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVG 207
++ LL ++L + + +L + GE + Q + +V+ G ++
Sbjct: 12 RNSLLIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKLFRMTPTGS 71
Query: 208 RCVGNYDNRG-SFGELALMYNTPRAATITATSP 239
V + RG SFGE + NTP + A +P
Sbjct: 72 EAVVSVFTRGESFGEAVALRNTPYPVSAEAVTP 104
>4I0B-A nrPDB
Length = 222
Score = 32.0 bits (71), Expect = 0.56, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 179 VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSF-GELALM-YNTPRAATITA 236
+I QG+ + Y I +G+ + +K + + +Y N+G F GEL L R+A + A
Sbjct: 42 LIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRA 101
Query: 237 TSPGALWGLDRVTFRRIIVKN 257
+ + + FR++I N
Sbjct: 102 KTACEVAEISYKKFRQLIQVN 122
>3KCC-A nrPDB
Length = 260
Score = 31.6 bits (70), Expect = 0.63, Method: Compositional matrix adjust.
Identities = 22/81 (27%), Positives = 40/81 (49%), Gaps = 2/81 (2%)
Query: 179 VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSF-GELALM-YNTPRAATITA 236
+I QG+ + Y I +G+ + +K + + +Y N+G F GEL L R+A + A
Sbjct: 80 LIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQERSAWVRA 139
Query: 237 TSPGALWGLDRVTFRRIIVKN 257
+ + + FR++I N
Sbjct: 140 KTACEVAEISYKKFRQLIQVN 160
>5H3O-A nrPDB
Length = 738
Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust.
Identities = 18/82 (21%), Positives = 42/82 (51%), Gaps = 4/82 (4%)
Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
E + + +F++ + +++++ + ++ G+ + +GD G Y++ RG + D
Sbjct: 491 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV---VD 547
Query: 205 GVGRCVGNYDNRGS-FGELALM 225
G+ V GS FGEL+++
Sbjct: 548 DDGKKVFVTLQEGSVFGELSIL 569
Score = 28.9 bits (63), Expect = 4.5, Method: Compositional matrix adjust.
Identities = 15/62 (24%), Positives = 32/62 (51%), Gaps = 9/62 (14%)
Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
+V++ G+ I +GD+ +IV+ G +++ V+++G G FGEL+
Sbjct: 517 QVFSPGDFICKKGDIGREMYIVKRGRLQV---------VDDDGKKVFVTLQEGSVFGELS 567
Query: 353 LV 354
++
Sbjct: 568 IL 569
>5I62-A nrPDB
Length = 534
Score = 29.3 bits (64), Expect = 3.1, Method: Compositional matrix adjust.
Identities = 19/66 (28%), Positives = 27/66 (40%), Gaps = 13/66 (19%)
Query: 207 GRCVGNYDNRGSFGELALM--YNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKM 264
G CVG Y + G LA+ Y P +WG VT R + + N K +
Sbjct: 411 GMCVGVYSTMRALGRLAMQERYYDP-----------DVWGEKMVTLRYLSIIENVKYHPL 459
Query: 265 YESFIE 270
E F++
Sbjct: 460 KEEFLD 465
>1DK5-A nrPDB
Length = 322
Score = 28.9 bits (63), Expect = 3.9, Method: Compositional matrix adjust.
Identities = 20/71 (28%), Positives = 33/71 (46%), Gaps = 6/71 (8%)
Query: 127 AESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDG 186
AES+I+H K D+ A D + + L +Q+ + + GE ++ Q +DG
Sbjct: 178 AESKILHEKISDK------AYSDDEVIRILATRSKAQLNATLNHYKDEHGEDILKQLEDG 231
Query: 187 DNFYVIDRGTF 197
D F + R T
Sbjct: 232 DEFVALLRATI 242
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
4X6Q-B nrPDB 614 e-176
3J4Q-B nrPDB 527 e-150
1CX4-A nrPDB 449 e-126
4DIN-B nrPDB 435 e-122
2QVS-B nrPDB 426 e-120
6BYS-B nrPDB 397 e-111
2QCS-B nrPDB 352 1e-97
5KBF-A nrPDB 343 7e-95
5J3U-A nrPDB 312 2e-85
5FET-A nrPDB 299 1e-81
5DYK-A nrPDB 297 5e-81
6FTF-B nrPDB 292 2e-79
4Z07-A nrPDB 292 2e-79
3SHR-A nrPDB 282 2e-76
5JAX-A nrPDB 156 2e-38
4QX5-A nrPDB 155 3e-38
6BQ8-A nrPDB 140 1e-33
4MGY-E nrPDB 139 2e-33
1O7F-A nrPDB 139 2e-33
4F7Z-A nrPDB 134 5e-32
5V4S-A nrPDB 133 2e-31
6CJQ-A nrPDB 128 4e-30
5JON-A nrPDB 124 7e-29
4CHV-A nrPDB 122 4e-28
3DKW-A nrPDB 117 1e-26
4EV0-A nrPDB 113 1e-25
4AVC-A nrPDB 81 6e-16
5XBY-A nrPDB 80 2e-15
5H78-A nrPDB 79 2e-15
5H77-A nrPDB 77 1e-14
Sequences not found previously or not previously below threshold:
5U6P-A nrPDB 119 2e-27
4ORF-A nrPDB 86 3e-17
4CYD-A nrPDB 85 6e-17
3I59-A nrPDB 84 7e-17
5H3O-A nrPDB 77 2e-14
4I0B-A nrPDB 74 1e-13
3KCC-A nrPDB 74 1e-13
3E97-A nrPDB 73 3e-13
5W5B-A nrPDB 66 3e-11
5VA1-A nrPDB 63 2e-10
2N7G-A nrPDB 63 3e-10
2OZ6-A nrPDB 62 4e-10
3H3Z-A nrPDB 61 1e-09
3UKN-A nrPDB 59 2e-09
5K7L-A nrPDB 56 3e-08
4F8A-A nrPDB 56 3e-08
3IWZ-A nrPDB 53 4e-07
4L11-A nrPDB 52 5e-07
2D93-A nrPDB 47 1e-05
3B02-A nrPDB 47 1e-05
2XKO-A nrPDB 46 2e-05
3LA7-A nrPDB 46 4e-05
1ZYB-A nrPDB 45 5e-05
2GAU-A nrPDB 45 7e-05
2FMY-A nrPDB 43 2e-04
1O5L-A nrPDB 41 7e-04
2ZCW-A nrPDB 39 0.004
1ATT-A nrPDB 37 0.019
4EB1-I nrPDB 36 0.027
5E44-A nrPDB 36 0.028
3E6B-A nrPDB 34 0.089
4FHA-A nrPDB 33 0.21
1Z5V-A nrPDB 32 0.50
1XKW-A nrPDB 32 0.52
6CXO-A nrPDB 29 3.0
5MMI-U nrPDB 29 4.4
>4X6Q-B nrPDB
Length = 416
Score = 614 bits (1582), Expect = e-176, Method: Composition-based stats.
Identities = 415/416 (99%), Positives = 416/416 (100%)
Query: 1 MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD
Sbjct: 1 MSIEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGD 60
Query: 61 AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120
AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP
Sbjct: 61 AGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNP 120
Query: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180
DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI
Sbjct: 121 DEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVI 180
Query: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPG 240
DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP+AATITATSPG
Sbjct: 181 DQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPKAATITATSPG 240
Query: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300
ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ
Sbjct: 241 ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ 300
Query: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360
IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA
Sbjct: 301 IIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRA 360
Query: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416
ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA
Sbjct: 361 ASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEPTA 416
>3J4Q-B nrPDB
Length = 402
Score = 527 bits (1357), Expect = e-150, Method: Composition-based stats.
Identities = 275/413 (66%), Positives = 328/413 (79%), Gaps = 17/413 (4%)
Query: 3 IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAG 62
I+IPAGLTELLQG+TVEVLR QP DL++FA+++FTRL+ E R+ + F T+
Sbjct: 4 IQIPAGLTELLQGYTVEVLRQQPPDLVDFAVEYFTRLR-EARRQESDTFIVSPTTFHTQE 62
Query: 63 AAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDE 122
++A I E+GE + +E PV ++FTRR SVCAE +NPDE
Sbjct: 63 SSAVPVI---------------EEDGESDSDSEDADLEVPVPSKFTRRVSVCAETFNPDE 107
Query: 123 EEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQ 182
EE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDAMFEK+VK EHVIDQ
Sbjct: 108 EEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDAMFEKIVKTDEHVIDQ 167
Query: 183 GDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGAL 242
GDDGDNFYVI+RGT+DI V D R VG YDNRGSFGELALMYNTPRAATI ATS G+L
Sbjct: 168 GDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYNTPRAATIIATSEGSL 227
Query: 243 WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQII 302
WGLDRVTFRRIIVKNNAKKRKM+ESFIES+P KSLE+SER+K+VDVIG K+Y DGE+II
Sbjct: 228 WGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIVDVIGEKIYKDGERII 287
Query: 303 AQGDLADSFFIVESGEVKITMKRKGKS-EVEENGAVEIARCFRGQYFGELALVTNKPRAA 361
AQG+ ADSF+I+ESGEV I ++ K KS + N VEIA C +GQYFGELALVTNKPRAA
Sbjct: 288 AQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQYFGELALVTNKPRAA 347
Query: 362 SAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIVEP 414
SA+A+G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +FG+N+D+++P
Sbjct: 348 SAYAVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFGSNLDLMDP 400
>1CX4-A nrPDB
Length = 305
Score = 449 bits (1155), Expect = e-126, Method: Composition-based stats.
Identities = 300/305 (98%), Positives = 303/305 (99%)
Query: 112 SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 171
SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK
Sbjct: 1 SVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEK 60
Query: 172 LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 231
LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA
Sbjct: 61 LVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRA 120
Query: 232 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 291
ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG
Sbjct: 121 ATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIG 180
Query: 292 TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
TKVYNDGEQIIAQGD ADSFFIVESGEV+ITMKRKGKS++EENGAVEIARC RGQYFGEL
Sbjct: 181 TKVYNDGEQIIAQGDSADSFFIVESGEVRITMKRKGKSDIEENGAVEIARCLRGQYFGEL 240
Query: 352 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 411
ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI
Sbjct: 241 ALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDI 300
Query: 412 VEPTA 416
VEPTA
Sbjct: 301 VEPTA 305
>4DIN-B nrPDB
Length = 381
Score = 435 bits (1117), Expect = e-122, Method: Composition-based stats.
Identities = 144/390 (36%), Positives = 209/390 (53%), Gaps = 42/390 (10%)
Query: 8 GLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGG 67
G+ ++L+ V + +P ++F +HF +L++E R+ AR
Sbjct: 26 GIQQVLKDCIVHLCISKPERPMKFLREHFEKLEKEENRQILAR----------------- 68
Query: 68 GIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDA 127
+S+S++ +E N PV+ RR V AE Y EE+ +
Sbjct: 69 -------------QKSNSQSDSHDEEVSPTPPN-PVVKARRRRGGVSAEVYT--EEDAVS 112
Query: 128 ESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGD 187
R + PK L +A +LF +LD + S + DAMF GE VI QG++GD
Sbjct: 113 YVRKVIPKDYKTMTALAKAISKNVLFAHLDDNERSDIFDAMFPVTHIAGETVIQQGNEGD 172
Query: 188 NFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDR 247
NFYV+D+G D+YV + V N GSFGELAL+Y TPRAAT+ A + LWG+DR
Sbjct: 173 NFYVVDQGEVDVYVNGE----WVTNISEGGSFGELALIYGTPRAATVKAKTDLKLWGIDR 228
Query: 248 VTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDL 307
++RRI++ + +KRKMYE F+ + L+SLE ERL V D + + DGE+I+ QG+
Sbjct: 229 DSYRRILMGSTLRKRKMYEEFLSKVSILESLEKWERLTVADALEPVQFEDGEKIVVQGEP 288
Query: 308 ADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIG 367
D F+I+ G + +R E VE+ R YFGE+AL+ N+PRAA+ A G
Sbjct: 289 GDDFYIITEGTASVLQRRSPNEEY-----VEVGRLGPSDYFGEIALLLNRPRAATVVARG 343
Query: 368 TVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
+KC+ +D FER+LGPC EI+KRNI Y
Sbjct: 344 PLKCVKLDRPRFERVLGPCSEILKRNIQRY 373
>2QVS-B nrPDB
Length = 310
Score = 426 bits (1096), Expect = e-120, Method: Composition-based stats.
Identities = 233/308 (75%), Positives = 268/308 (87%), Gaps = 1/308 (0%)
Query: 108 TRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDA 167
TRR SVCAE +NPDEEE+D + R++HPKTD+QR RLQEACKDILLFKNLD EQ+SQVLDA
Sbjct: 1 TRRVSVCAETFNPDEEEEDNDPRVVHPKTDEQRCRLQEACKDILLFKNLDQEQLSQVLDA 60
Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYN 227
MFEK+VK EHVIDQGDDGDNFYVI+RGT+DI V D R VG YDNRGSFGELALMYN
Sbjct: 61 MFEKIVKTDEHVIDQGDDGDNFYVIERGTYDILVTKDNQTRSVGQYDNRGSFGELALMYN 120
Query: 228 TPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVV 287
TPRAATI ATS G+LWGLDRVTFRRIIVKNNAKKRKM+ESFIES+P KSLE+SER+K+V
Sbjct: 121 TPRAATIIATSEGSLWGLDRVTFRRIIVKNNAKKRKMFESFIESVPLFKSLEMSERMKIV 180
Query: 288 DVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKS-EVEENGAVEIARCFRGQ 346
DVIG K+Y DGE+IIAQG+ ADSF+I+ESGEV I ++ K KS + N VEIA C +GQ
Sbjct: 181 DVIGEKIYKDGERIIAQGEKADSFYIIESGEVSILIRSKTKSNKNGGNQEVEIAHCHKGQ 240
Query: 347 YFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 406
YFGELALVTNKPRAASA+ +G VKCL MDVQAFERLLGPCM+IMKRNI+ YEEQLV +FG
Sbjct: 241 YFGELALVTNKPRAASAYGVGDVKCLVMDVQAFERLLGPCMDIMKRNISHYEEQLVKMFG 300
Query: 407 TNMDIVEP 414
+N+D+++P
Sbjct: 301 SNLDLMDP 308
>6BYS-B nrPDB
Length = 379
Score = 397 bits (1020), Expect = e-111, Method: Composition-based stats.
Identities = 136/389 (34%), Positives = 203/389 (52%), Gaps = 42/389 (10%)
Query: 9 LTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGG 68
+ LL+ V++ +P + F ++F +L++E ++
Sbjct: 25 IQALLKDSIVQLCTARPERPMAFLREYFEKLEKEEAKQIQN------------------- 65
Query: 69 IPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAE 128
++ S E+ N PV+ RR ++ AE Y EE+ +
Sbjct: 66 -----------LQKAGSRADSREDEISPPPPN-PVVKGRRRRGAISAEVYT--EEDAASY 111
Query: 129 SRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDN 188
R + PK L +A + +LF +LD + S + DAMF GE VI QGD+GDN
Sbjct: 112 VRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDN 171
Query: 189 FYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRV 248
FYVID+G D+YV + + GSFGELAL+Y TPRAAT+ A + LWG+DR
Sbjct: 172 FYVIDQGEMDVYVNNE----WATSVGEGGSFGELALIYGTPRAATVKAKTNVKLWGIDRD 227
Query: 249 TFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLA 308
++RRI++ + +KRKMYE F+ + L+SL+ ERL V D + + DG++I+ QG+
Sbjct: 228 SYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERLTVADALEPVQFEDGQKIVVQGEPG 287
Query: 309 DSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT 368
D FFI+ G + +R E VE+ R YFGE+AL+ N+PRAA+ A G
Sbjct: 288 DEFFIILEGSAAVLQRRSENEE-----FVEVGRLGPSDYFGEIALLMNRPRAATVVARGP 342
Query: 369 VKCLAMDVQAFERLLGPCMEIMKRNIATY 397
+KC+ +D FER+LGPC +I+KRNI Y
Sbjct: 343 LKCVKLDRPRFERVLGPCSDILKRNIQQY 371
Score = 111 bits (276), Expect = 9e-25, Method: Composition-based stats.
Identities = 46/177 (25%), Positives = 79/177 (44%), Gaps = 6/177 (3%)
Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
+I R A+V A+ + D+ RI+ T +R +E + + ++LD
Sbjct: 200 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDK 259
Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNY--DNR 216
+ V DA+ ++G+ ++ QG+ GD F++I G+ + + V
Sbjct: 260 WERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPS 319
Query: 217 GSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV---KNNAKKRKMYESFIE 270
FGE+AL+ N PRAAT+ A P LDR F R++ + + Y SF+
Sbjct: 320 DYFGEIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 376
>2QCS-B nrPDB
Length = 291
Score = 352 bits (903), Expect = 1e-97, Method: Composition-based stats.
Identities = 122/293 (41%), Positives = 173/293 (59%), Gaps = 11/293 (3%)
Query: 105 NRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQV 164
RR ++ AE Y EE+ + R + PK L +A + +LF +LD + S +
Sbjct: 1 KGRRRRGAISAEVYT--EEDAASYVRKVIPKDYKTMAALAKAIEKNVLFSHLDDNERSDI 58
Query: 165 LDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELAL 224
DAMF GE VI QGD+GDNFYVID+G D+YV + + GSFGELAL
Sbjct: 59 FDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNE----WATSVGEGGSFGELAL 114
Query: 225 MYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERL 284
+Y TPRAAT+ A + LWG+DR ++RRI++ + +KRKMYE F+ + L+SL+ ERL
Sbjct: 115 IYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDKWERL 174
Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
V D + + DG++I+ QG+ D FFI+ G + +R E VE+ R
Sbjct: 175 TVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEE-----FVEVGRLGP 229
Query: 345 GQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
YFGE+AL+ N+P+AA+ A G +KC+ +D FER+LGPC +I+KRNI Y
Sbjct: 230 SDYFGEIALLMNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQY 282
Score = 110 bits (275), Expect = 1e-24, Method: Composition-based stats.
Identities = 45/177 (25%), Positives = 79/177 (44%), Gaps = 6/177 (3%)
Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
+I R A+V A+ + D+ RI+ T +R +E + + ++LD
Sbjct: 111 ELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLDK 170
Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNY--DNR 216
+ V DA+ ++G+ ++ QG+ GD F++I G+ + + V
Sbjct: 171 WERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPS 230
Query: 217 GSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV---KNNAKKRKMYESFIE 270
FGE+AL+ N P+AAT+ A P LDR F R++ + + Y SF+
Sbjct: 231 DYFGEIALLMNRPKAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVS 287
>5KBF-A nrPDB
Length = 301
Score = 343 bits (880), Expect = 7e-95, Method: Composition-based stats.
Identities = 113/300 (37%), Positives = 174/300 (58%), Gaps = 12/300 (4%)
Query: 106 RFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVL 165
+R SV AEAY ++ D ++ K + ++ +++EA + LF +L+ ++ ++
Sbjct: 3 GQKKRLSVSAEAYGDWNKKIDNFIPKVYKKDEKEKAKIREALNESFLFNHLNKKEFEIIV 62
Query: 166 DAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELAL 224
+A F+K V++G ++I++GD GD YVID+G +IY K + + ++ FGELAL
Sbjct: 63 NAFFDKNVEKGVNIINEGDYGDLLYVIDQGEVEIYKTKENNKKEVLTVLKSKDVFGELAL 122
Query: 225 MYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERL 284
+YN+ RAAT TA + LW LDR +F II AKKRKMYE + + LK ++ ER
Sbjct: 123 LYNSKRAATATALTKCHLWALDRESFTYIIKDMVAKKRKMYEDILSHVNILKDMDPYERC 182
Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
KV D + +K YNDGE II +G+ D+FFI+ G + K I +
Sbjct: 183 KVADCLKSKSYNDGEIIIKEGEEGDTFFILIDGNAVASKDNKV-----------IKTYTK 231
Query: 345 GQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVAL 404
G YFGELAL+ NKPRAA+ A + + +D ++F+RLLGP +I+ RN+ Y++ L L
Sbjct: 232 GDYFGELALLKNKPRAATIKAQNFCQVVYLDRKSFKRLLGPIEDILHRNVENYKKVLNEL 291
>5J3U-A nrPDB
Length = 261
Score = 312 bits (798), Expect = 2e-85, Method: Composition-based stats.
Identities = 95/266 (35%), Positives = 151/266 (56%), Gaps = 5/266 (1%)
Query: 132 IHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYV 191
++ K + Q+ +L+ + LF +LD + ++ V+ AM EK ++ +I +GDDG+ Y+
Sbjct: 1 VYEKDEGQKEQLERILRQSFLFNSLDEKDLNTVILAMQEKKIEASTCLIREGDDGECLYI 60
Query: 192 IDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
+ G + DG R V +FGELAL+YN PRAAT+T+ S LW L R TF
Sbjct: 61 VQSGELNCSKLIDGEERVVKVVGPGDAFGELALLYNAPRAATVTSVSACDLWELGRDTFN 120
Query: 252 RIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSF 311
I+ K+R MY+SF++S+ L ++ ER KV D + T+++ DG I+ QG+L D F
Sbjct: 121 AIVKDAATKRRSMYDSFLKSVHILDGMDAYERGKVADALRTEMFTDGAYIVRQGELGDVF 180
Query: 312 FIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKC 371
+IVE G T KS +E+ + G YFGELAL+ +PRAA+ A G K
Sbjct: 181 YIVEEGSAVAT-----KSFGPGQPPIEVKKYQAGDYFGELALINEEPRAANVIAHGICKV 235
Query: 372 LAMDVQAFERLLGPCMEIMKRNIATY 397
++ ++F+RL+G +++ + + Y
Sbjct: 236 ACLERKSFKRLMGSVQDLLSKKASEY 261
Score = 112 bits (280), Expect = 3e-25, Method: Composition-based stats.
Identities = 47/174 (27%), Positives = 83/174 (47%), Gaps = 14/174 (8%)
Query: 99 FNAPVINRFTRRASVCA-EAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLD 157
+NAP R A+V + A + E D + I+ +R+ K + + +D
Sbjct: 95 YNAP------RAATVTSVSACDLWELGRDTFNAIVKDAATKRRSMYDSFLKSVHILDGMD 148
Query: 158 PEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNYD 214
+ +V DA+ ++ +G +++ QG+ GD FY+++ G+ + K G G+ V Y
Sbjct: 149 AYERGKVADALRTEMFTDGAYIVRQGELGDVFYIVEEGSA-VATKSFGPGQPPIEVKKYQ 207
Query: 215 NRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII---VKNNAKKRKMY 265
FGELAL+ PRAA + A + L+R +F+R++ +KK Y
Sbjct: 208 AGDYFGELALINEEPRAANVIAHGICKVACLERKSFKRLMGSVQDLLSKKASEY 261
>5FET-A nrPDB
Length = 847
Score = 299 bits (766), Expect = 1e-81, Method: Composition-based stats.
Identities = 82/282 (29%), Positives = 141/282 (50%), Gaps = 18/282 (6%)
Query: 124 EDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQG 183
ED + R K + ++ + K+ L+ L+ ++ + + M + K G+ VI QG
Sbjct: 27 EDHLQLR---EKLSEDIEMIKASLKNNLVCSTLNDNEILTLSNYMQFFVFKGGDLVIKQG 83
Query: 184 DDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALW 243
+ G F++I+ G FD+YV + V + SFGE AL++NT R+ATI A + G LW
Sbjct: 84 EKGSYFFIINSGKFDVYVN----DKKVKSMGKGSSFGEAALIHNTQRSATIMAETDGTLW 139
Query: 244 GLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIA 303
G+ R TFR + + + + SFI+S+ L +++ + + +++ GE I+
Sbjct: 140 GVQRSTFRATLKQLSNRNFNENRSFIDSVSVFDMLTEAQKNMITNACVIQMFKPGETIVK 199
Query: 304 QGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA 363
QGD D FI++ G+ + + K EI +G YFGE AL+ ++PR+A+
Sbjct: 200 QGDYGDVLFILKEGKATVFINDK-----------EIRVLNKGSYFGERALLYDEPRSATI 248
Query: 364 HAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALF 405
A C ++ + +LG ++ RNI T Q +F
Sbjct: 249 IAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIF 290
Score = 128 bits (322), Expect = 3e-30, Method: Composition-based stats.
Identities = 51/262 (19%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFY-VIDRGTFD 198
RN + EA + +F+ EQ++ + D + H++ + Y ++ G +
Sbjct: 277 RNIMTEALQQSEIFRQFSAEQLNDLADTAIVRDYPANYHILHKDKVKSVKYLIVLEGKVE 336
Query: 199 IYVKCDGVGRCVGNYDNRGSFGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKN 257
+++ +G SFG+ ++ + T+ + + + + N
Sbjct: 337 LFL----DDESIGILTRGKSFGDQYVLNQKQKFRHTVKSLDVCKIALITESCLADCLGDN 392
Query: 258 NA---KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIV 314
N +S I+ + + L + +++ T Y +G+ II +G++ F+I+
Sbjct: 393 NIDASIDHNNKKSIIKKMYIFRYLSEQQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYII 452
Query: 315 ESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLA 373
++GEV++T K + + YFGE AL+ ++PR AS + +V+C
Sbjct: 453 KNGEVEVTKNGK-----------RLRTLGKNDYFGERALLYDEPRTASIISKATSVECWF 501
Query: 374 MDVQAFERLL-GPCMEIMKRNI 394
+D F +++ GP + ++ I
Sbjct: 502 VDKSVFLQIIQGPMLTHLEERI 523
Score = 120 bits (301), Expect = 1e-27, Method: Composition-based stats.
Identities = 52/289 (17%), Positives = 110/289 (38%), Gaps = 19/289 (6%)
Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
A +I+ R A++ AE + + ++ N + + +F L
Sbjct: 117 EAALIHNTQRSATIMAETDGTLWGVQRSTFRATLKQLSNRNFNENRSFIDSVSVFDMLTE 176
Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGS 218
Q + + +A ++ K GE ++ QGD GD +++ G +++ + + +
Sbjct: 177 AQKNMITNACVIQMFKPGETIVKQGDYGDVLFILKEGKATVFIN----DKEIRVLNKGSY 232
Query: 219 FGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK-RKMYESFIESLPFLKS 277
FGE AL+Y+ PR+ATI A P A + R ++ R + ++ +
Sbjct: 233 FGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIFRQ 292
Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGD-LADSFFIVESGEVKITMKRKGKSEVEENGA 336
+ + D + Y I+ + + + IV G+V++ + +
Sbjct: 293 FSAEQLNDLADTAIVRDYPANYHILHKDKVKSVKYLIVLEGKVELFLDDES--------- 343
Query: 337 VEIARCFRGQYFGELALVTNKPR-AASAHAIGTVKCLAMDVQAFERLLG 384
I RG+ FG+ ++ K + + ++ K + LG
Sbjct: 344 --IGILTRGKSFGDQYVLNQKQKFRHTVKSLDVCKIALITESCLADCLG 390
Score = 109 bits (271), Expect = 3e-24, Method: Composition-based stats.
Identities = 46/200 (23%), Positives = 84/200 (42%), Gaps = 29/200 (14%)
Query: 110 RASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMF 169
+ ++ E+ D D+ I N + K + +F+ L +Q + +++A
Sbjct: 376 KIALITESCLADCLGDNNIDASI------DHNNKKSIIKKMYIFRYLSEQQCNLLIEAFR 429
Query: 170 EKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTP 229
+EG+++I +G+ G FY+I G ++ + + FGE AL+Y+ P
Sbjct: 430 TTRYEEGDYIIQEGEVGSRFYIIKNGEVEVTKNG----KRLRTLGKNDYFGERALLYDEP 485
Query: 230 RAATITA-TSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVD 288
R A+I + + W +D+ F +II P L LE ER+K+ D
Sbjct: 486 RTASIISKATSVECWFVDKSVFLQIIQG----------------PMLTHLE--ERIKMQD 527
Query: 289 VIGTKVYNDGEQIIAQGDLA 308
+ E+II +G
Sbjct: 528 TKVEMHELETERIIGRGTFG 547
>5DYK-A nrPDB
Length = 853
Score = 297 bits (760), Expect = 5e-81, Method: Composition-based stats.
Identities = 80/282 (28%), Positives = 139/282 (49%), Gaps = 18/282 (6%)
Query: 124 EDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQG 183
ED E R K + + ++ + K+ L+ L+ ++ + + M + K G VI QG
Sbjct: 33 EDHLELR---EKLSEDIDMIKTSLKNNLVCSTLNDNEILTLSNYMQFFVFKSGNLVIKQG 89
Query: 184 DDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALW 243
+ G F++I+ G FD+YV + V SFGE AL++NT R+ATI A + G LW
Sbjct: 90 EKGSYFFIINSGKFDVYVN----DKKVKTMGKGSSFGEAALIHNTQRSATIIAETDGTLW 145
Query: 244 GLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIA 303
G+ R TFR + + + + +FI+S+ L +++ + + + + GE I+
Sbjct: 146 GVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTEAQKNMITNACVIQNFKSGETIVK 205
Query: 304 QGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASA 363
QGD D +I++ G+ + + + EI +G YFGE AL+ ++PR+A+
Sbjct: 206 QGDYGDVLYILKEGKATVYINDE-----------EIRVLEKGSYFGERALLYDEPRSATI 254
Query: 364 HAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALF 405
A C ++ + +LG ++ RNI T Q +F
Sbjct: 255 IAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIF 296
Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats.
Identities = 55/290 (18%), Positives = 107/290 (36%), Gaps = 19/290 (6%)
Query: 100 NAPVINRFTRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
A +I+ R A++ AE + + ++ N + + +F L
Sbjct: 123 EAALIHNTQRSATIIAETDGTLWGVQRSTFRATLKQLSNRNFNENRTFIDSVSVFDMLTE 182
Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGS 218
Q + + +A + K GE ++ QGD GD Y++ G +Y+ + + +
Sbjct: 183 AQKNMITNACVIQNFKSGETIVKQGDYGDVLYILKEGKATVYINDEE----IRVLEKGSY 238
Query: 219 FGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKK-RKMYESFIESLPFLKS 277
FGE AL+Y+ PR+ATI A P A + R ++ R + ++ K
Sbjct: 239 FGERALLYDEPRSATIIAKEPTACASICRKLLNIVLGNLQVVLFRNIMTEALQQSEIFKQ 298
Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVE-SGEVKITMKRKGKSEVEENGA 336
+ + D + Y I+ + + +I+ G+V++ +
Sbjct: 299 FSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVELFLDD----------- 347
Query: 337 VEIARCFRGQYFGELALVTNK-PRAASAHAIGTVKCLAMDVQAFERLLGP 385
I RG FG+ ++ K P + ++ K + LG
Sbjct: 348 TSIGILSRGMSFGDQYVLNQKQPFKHTIKSLEVCKIALITETCLADCLGN 397
Score = 125 bits (314), Expect = 3e-29, Method: Composition-based stats.
Identities = 53/262 (20%), Positives = 112/262 (42%), Gaps = 22/262 (8%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVI-DRGTFD 198
RN + EA + +FK +Q++ + D + +++ + Y+I G +
Sbjct: 283 RNIMTEALQQSEIFKQFSGDQLNDLADTAIVRDYPANYNILHKDKVKSVKYIIVLEGKVE 342
Query: 199 IYVKCDGVGRCVGNYDNRGSFGELALMYN-TPRAATITATSPGALWGLDRVTFRRIIVKN 257
+++ +G SFG+ ++ P TI + + + + N
Sbjct: 343 LFL----DDTSIGILSRGMSFGDQYVLNQKQPFKHTIKSLEVCKIALITETCLADCLGNN 398
Query: 258 NA---KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIV 314
N +S I+ + + L + +++ T Y +G+ II +G++ F+I+
Sbjct: 399 NIDASIDYNNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYII 458
Query: 315 ESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLA 373
++GEV+I +K + + YFGE AL+ ++PR AS + + V+C
Sbjct: 459 KNGEVEIVKNKK-----------RLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWF 507
Query: 374 MDVQAFERLL-GPCMEIMKRNI 394
+D F +++ GP + ++ I
Sbjct: 508 VDKSVFLQIIQGPMLAHLEERI 529
Score = 105 bits (262), Expect = 4e-23, Method: Composition-based stats.
Identities = 42/169 (24%), Positives = 74/169 (43%), Gaps = 23/169 (13%)
Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY 200
N + K + +F+ L +Q + +++A +EG+++I +G+ G FY+I G +I
Sbjct: 407 NNKKSIIKKMYIFRYLTDKQCNLLIEAFRTTRYEEGDYIIQEGEVGSRFYIIKNGEVEIV 466
Query: 201 VKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATS-PGALWGLDRVTFRRIIVKNNA 259
+ + FGE AL+Y+ PR A++ + W +D+ F +II
Sbjct: 467 KN----KKRLRTLGKNDYFGERALLYDEPRTASVISKVNNVECWFVDKSVFLQIIQG--- 519
Query: 260 KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLA 308
P L LE ER+K+ D + E+II +G
Sbjct: 520 -------------PMLAHLE--ERIKMQDTKVEMDELETERIIGRGTFG 553
>6FTF-B nrPDB
Length = 304
Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats.
Identities = 73/289 (25%), Positives = 137/289 (47%), Gaps = 14/289 (4%)
Query: 106 RFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVL 165
RR +V +E +P E+ K++D+ N + + +LF L+ + + V
Sbjct: 1 GRNRRRTVRSEGIDP--EKAKLYQAPYFEKSEDEMNLITKLLTHNVLFSFLNTKDIKVVA 58
Query: 166 DAMFEKLVKEGEHVIDQGDDGDN-FYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELAL 224
AM K + +++ G N Y+I G DI +G + + GEL L
Sbjct: 59 GAMQRATFKHDDCIMEAGQTTCNKLYIIQSGHADII--KEGQKVYLKT--EGTAVGELEL 114
Query: 225 MYNTPRAATITATSPGAL-WGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSER 283
MY+TP AT+ + + W LDR T+R +++ ++R+ Y F+ ++PFL L+ E+
Sbjct: 115 MYDTPVVATVKVCTDELIAWVLDRDTYRNLVMGTAIRRRETYIQFLANVPFLGGLDSYEK 174
Query: 284 LKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCF 343
L++ D + ++ ++ GE II G+ + +I+ G V++ + + ++
Sbjct: 175 LQLADALSSEEFSPGEYIIHYGEEGEWLYIIMEGTVEVIGRD------ADGEPTKVCEFT 228
Query: 344 RGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKR 392
+G + GEL + N A A V ++ + FE LGP ++++KR
Sbjct: 229 QGDHIGELEFLNNHRTVADVVATTHVITAKLNRRHFEMCLGPVIDVLKR 277
>4Z07-A nrPDB
Length = 262
Score = 292 bits (747), Expect = 2e-79, Method: Composition-based stats.
Identities = 78/259 (30%), Positives = 128/259 (49%), Gaps = 9/259 (3%)
Query: 131 IIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFY 190
+PK+ ++ ++EA D KNL+ Q+ +++D M+ + +I +GD G Y
Sbjct: 8 PFYPKSPQSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVY 67
Query: 191 VIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTF 250
V++ G ++ +GV C FGELA++YN R AT+ LW +DR F
Sbjct: 68 VMEDGKVEV--TKEGVKLC--TMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCF 123
Query: 251 RRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADS 310
+ I+++ K Y F++S+P +SL K+ DV+ Y +GE II QG D+
Sbjct: 124 QTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDT 183
Query: 311 FFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVK 370
FFI+ G V +T + + V + +G +FGE AL R A+ A V
Sbjct: 184 FFIISKGTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVT 238
Query: 371 CLAMDVQAFERLLGPCMEI 389
CL +D +F+ L+G ++
Sbjct: 239 CLVIDRDSFKHLIGGLDDV 257
Score = 127 bits (319), Expect = 8e-30, Method: Composition-based stats.
Identities = 39/162 (24%), Positives = 66/162 (40%), Gaps = 5/162 (3%)
Query: 108 TRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLD 166
TR A+V + I+ + E K + F++L E +S++ D
Sbjct: 102 TRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLAD 161
Query: 167 AMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNYDNRGSFGELA 223
+ E + GE++I QG GD F++I +GT ++ + D + FGE A
Sbjct: 162 VLEETHYENGEYIIRQGARGDTFFIISKGTVNV-TREDSPSEDPVFLRTLGKGDWFGEKA 220
Query: 224 LMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMY 265
L R A + A +DR +F+ +I + K Y
Sbjct: 221 LQGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAY 262
>3SHR-A nrPDB
Length = 299
Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats.
Identities = 77/257 (29%), Positives = 128/257 (49%), Gaps = 9/257 (3%)
Query: 133 HPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVI 192
K++ ++ ++EA D KNL+ Q+ +++D M+ + +I +GD G YV+
Sbjct: 27 FTKSERSKDLIKEAILDNDFMKNLELSQIQEIVDCMYPVEYGKDSCIIKEGDVGSLVYVM 86
Query: 193 DRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
+ G ++ +GV C FGELA++YN R AT+ LW +DR F+
Sbjct: 87 EDGKVEV--TKEGVKLC--TMGPGKVFGELAILYNCTRTATVKTLVNVKLWAIDRQCFQT 142
Query: 253 IIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFF 312
I+++ K Y F++S+P +SL K+ DV+ Y +GE II QG D+FF
Sbjct: 143 IMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFF 202
Query: 313 IVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCL 372
I+ G+V +T + + V + +G +FGE AL R A+ A V CL
Sbjct: 203 IISKGKVNVT-----REDSPNEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCL 257
Query: 373 AMDVQAFERLLGPCMEI 389
+D +F+ L+G ++
Sbjct: 258 VIDRDSFKHLIGGLDDV 274
Score = 129 bits (323), Expect = 3e-30, Method: Composition-based stats.
Identities = 38/163 (23%), Positives = 65/163 (39%), Gaps = 3/163 (1%)
Query: 108 TRRASVCAEA-YNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLD 166
TR A+V + I+ + E K + F++L E +S++ D
Sbjct: 119 TRTATVKTLVNVKLWAIDRQCFQTIMMRTGLIKHTEYMEFLKSVPTFQSLPEEILSKLAD 178
Query: 167 AMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYV--KCDGVGRCVGNYDNRGSFGELAL 224
+ E + GE++I QG GD F++I +G ++ + + FGE AL
Sbjct: 179 VLEETHYENGEYIIRQGARGDTFFIISKGKVNVTREDSPNEDPVFLRTLGKGDWFGEKAL 238
Query: 225 MYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYES 267
R A + A +DR +F+ +I + K YE
Sbjct: 239 QGEDVRTANVIAAEAVTCLVIDRDSFKHLIGGLDDVSNKAYED 281
>5JAX-A nrPDB
Length = 135
Score = 156 bits (393), Expect = 2e-38, Method: Composition-based stats.
Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 5/133 (3%)
Query: 257 NNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVES 316
K Y F++S+P +SL K+ DV+ Y +GE II QG D+FFI+
Sbjct: 3 TGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISK 62
Query: 317 GEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDV 376
G V +T + + V + +G +FGE AL R A+ A V CL +D
Sbjct: 63 GTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR 117
Query: 377 QAFERLLGPCMEI 389
+F+ L+G ++
Sbjct: 118 DSFKHLIGGLDDV 130
Score = 121 bits (302), Expect = 8e-28, Method: Composition-based stats.
Identities = 34/130 (26%), Positives = 58/130 (44%), Gaps = 4/130 (3%)
Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
+ E K + F++L E +S++ D + E + GE++I QG GD F++I +GT +
Sbjct: 7 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66
Query: 199 IYVKCDGVGR---CVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV 255
+ + D + FGE AL R A + A +DR +F+ +I
Sbjct: 67 V-TREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIG 125
Query: 256 KNNAKKRKMY 265
+ K Y
Sbjct: 126 GLDDVSNKAY 135
>4QX5-A nrPDB
Length = 153
Score = 155 bits (391), Expect = 3e-38, Method: Composition-based stats.
Identities = 41/133 (30%), Positives = 63/133 (47%), Gaps = 5/133 (3%)
Query: 257 NNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVES 316
K Y F++S+P +SL K+ DV+ Y +GE II QG D+FFI+
Sbjct: 3 TGLIKHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISK 62
Query: 317 GEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDV 376
G V +T + + V + +G +FGE AL R A+ A V CL +D
Sbjct: 63 GTVNVT-----REDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDR 117
Query: 377 QAFERLLGPCMEI 389
+F+ L+G ++
Sbjct: 118 DSFKHLIGGLDDV 130
Score = 122 bits (306), Expect = 2e-28, Method: Composition-based stats.
Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 4/132 (3%)
Query: 139 QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFD 198
+ E K + F++L E +S++ D + E + GE++I QG GD F++I +GT +
Sbjct: 7 KHTEYMEFLKSVPTFQSLPEEILSKLADVLEETHYENGEYIIRQGARGDTFFIISKGTVN 66
Query: 199 IYVKCDGVGR---CVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIV 255
+ + D + FGE AL R A + A +DR +F+ +I
Sbjct: 67 V-TREDSPSEDPVFLRTLGKGDWFGEKALQGEDVRTANVIAAEAVTCLVIDRDSFKHLIG 125
Query: 256 KNNAKKRKMYES 267
+ K YE
Sbjct: 126 GLDDVSNKAYED 137
>6BQ8-A nrPDB
Length = 152
Score = 140 bits (352), Expect = 1e-33, Method: Composition-based stats.
Identities = 40/132 (30%), Positives = 73/132 (55%), Gaps = 6/132 (4%)
Query: 261 KRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVK 320
+ + Y +F+ S+ LK+L + K++D + + Y+ G+ II +G+ +FFI+ G+VK
Sbjct: 7 RDEQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVK 66
Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIG-TVKCLAMDVQAF 379
+T +G + I +G+YFGE AL+++ R+A+ A V CL +D + F
Sbjct: 67 VTQSTEGH-----DQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETF 121
Query: 380 ERLLGPCMEIMK 391
+ +G E+ K
Sbjct: 122 NQTVGTFEELQK 133
Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats.
Identities = 26/118 (22%), Positives = 60/118 (50%), Gaps = 3/118 (2%)
Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY 200
+ + + + L KNL +++++++D + + +G+++I +G++G F+++ +G +
Sbjct: 9 EQYRNFLRSVSLLKNLPEDKLTKIIDCLEVEYYDKGDYIIREGEEGSTFFILAKGKVKVT 68
Query: 201 VKCDGVG--RCVGNYDNRGSFGELALMYNTPRAATITATS-PGALWGLDRVTFRRIIV 255
+G + + FGE AL+ + R+A I A A +DR TF + +
Sbjct: 69 QSTEGHDQPQLIKTLQKGEYFGEKALISDDVRSANIIAEENDVACLVIDRETFNQTVG 126
>4MGY-E nrPDB
Length = 694
Score = 139 bits (350), Expect = 2e-33, Method: Composition-based stats.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 19/162 (11%)
Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
DA R+I K QR + L+ ++L K L +++ VL +FE K G
Sbjct: 8 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 65
Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
+ +QG++G ++Y+I +G+ ++ + GV + D+ FG+LAL+ + PRAA+I
Sbjct: 66 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGQLALVNDAPRAASIVLR 122
Query: 238 SP-GALWGLDRVTFRRIIVKNNAKKRKMYES-----FIESLP 273
+D+ F RI+ A ++ E +E +P
Sbjct: 123 EDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVP 164
Score = 77.9 bits (190), Expect = 8e-15, Method: Composition-based stats.
Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 265 YESFIESLPFLKSLEVSERLKVVDVIGTKVY-NDGEQIIAQGDLADSFFIVESGEVKITM 323
Y+ + + L L + + ++ V+ + + G + QG+ S++I+ G V + +
Sbjct: 31 YDELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVI 89
Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-VKCLAMDVQAFERL 382
KG + G FG+LALV + PRAAS L +D + F R+
Sbjct: 90 YGKG----------VVCTLHEGDDFGQLALVNDAPRAASIVLREDNCHFLRVDKEDFNRI 139
Query: 383 LGPCMEIMKRNIATYEEQLV 402
L R ++ LV
Sbjct: 140 LRDVEANTVRLKEHDQDVLV 159
>1O7F-A nrPDB
Length = 469
Score = 139 bits (349), Expect = 2e-33, Method: Composition-based stats.
Identities = 44/162 (27%), Positives = 78/162 (48%), Gaps = 19/162 (11%)
Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
DA R+I K QR + L+ ++L K L +++ VL +FE K G
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370
Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
+ +QG++G ++Y+I +G+ ++ + GV + D+ FG+LAL+ + PRAA+I
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIVLR 427
Query: 238 SP-GALWGLDRVTFRRIIVKNNAKKRKMYES-----FIESLP 273
+D+ F RI+ A ++ E +E +P
Sbjct: 428 EDNCHFLRVDKEDFNRILRDVEANTVRLKEHDQDVLVLEKVP 469
Score = 89.1 bits (219), Expect = 3e-18, Method: Composition-based stats.
Identities = 41/212 (19%), Positives = 85/212 (40%), Gaps = 20/212 (9%)
Query: 97 GAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNL 156
G+ P++ + AE ++ ++ + + + K + F+
Sbjct: 1 GSPGIPMVAAHAAHSQSSAEWIACLDKRP-------LERSSEDVDIIFTRLKGVKAFEKF 53
Query: 157 DPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNY 213
P + Q+ + + +++G + QGD G N+Y + G+ D+ V + +
Sbjct: 54 HPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTL 113
Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
+FGE +++ NTPR ATI L +++ F+ + +K + Y + + + P
Sbjct: 114 GIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKALW-----EKYRQYMAGLLAPP 167
Query: 274 FLKSLEVSERLKVVDVIGTKVYNDGEQIIAQG 305
+ V E D I K E+I+ G
Sbjct: 168 Y----GVMETGSNNDRIPDKENVPSEKILRAG 195
Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats.
Identities = 33/140 (23%), Positives = 58/140 (41%), Gaps = 13/140 (9%)
Query: 265 YESFIESLPFLKSLEVSERLKVVDVIGTKVY-NDGEQIIAQGDLADSFFIVESGEVKITM 323
Y+ + + L L + + ++ V+ + + G + QG+ S++I+ G V + +
Sbjct: 336 YDELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVI 394
Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-VKCLAMDVQAFERL 382
KG + G FG+LALV + PRAAS L +D + F R+
Sbjct: 395 YGKG----------VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDFNRI 444
Query: 383 LGPCMEIMKRNIATYEEQLV 402
L R ++ LV
Sbjct: 445 LRDVEANTVRLKEHDQDVLV 464
Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats.
Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 5/114 (4%)
Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
++ + + + ++ + G + QGD+ +++ V +G + + K
Sbjct: 44 LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVS 99
Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERL 382
AV I G FGE +++ N PR A+ + + L ++ + F+ L
Sbjct: 100 ETSSHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKAL 152
>4F7Z-A nrPDB
Length = 999
Score = 134 bits (338), Expect = 5e-32, Method: Composition-based stats.
Identities = 43/162 (26%), Positives = 77/162 (47%), Gaps = 19/162 (11%)
Query: 126 DAESRIIHPKTDDQR--NRLQEACKDILLFKNLD------PEQMSQVLDAMFEKLVKEGE 177
DA R+I K QR + L+ ++L K L +++ VL +FE K G
Sbjct: 313 DAHMRMILRKPPGQRTVDDLEIIYDELLHIKALSHLSTTVKRELAGVL--IFESHAKGGT 370
Query: 178 HVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITAT 237
+ +QG++G ++Y+I +G+ ++ + GV + D+ FG+LAL+ + PRAA+I
Sbjct: 371 VLFNQGEEGTSWYIILKGSVNVVIYGKGVVCTLHEGDD---FGKLALVNDAPRAASIVLR 427
Query: 238 SP-GALWGLDRVTFRRIIVKNNAKKRKMYES-----FIESLP 273
+D+ RI+ A ++ E +E +P
Sbjct: 428 EDNCHFLRVDKEDGNRILRDVEANTVRLKEHDQDVLVLEKVP 469
Score = 89.1 bits (219), Expect = 3e-18, Method: Composition-based stats.
Identities = 41/212 (19%), Positives = 85/212 (40%), Gaps = 20/212 (9%)
Query: 97 GAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNL 156
G+ P++ + AE ++ ++ + + + K + F+
Sbjct: 1 GSPGIPMVAAHAAHSQSSAEWIACLDKRP-------LERSSEDVDIIFTRLKGVKAFEKF 53
Query: 157 DPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGR---CVGNY 213
P + Q+ + + +++G + QGD G N+Y + G+ D+ V + +
Sbjct: 54 HPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDVKVSETSSHQDAVTICTL 113
Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
+FGE +++ NTPR ATI L +++ F+ + +K + Y + + + P
Sbjct: 114 GIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKALW-----EKYRQYMAGLLAPP 167
Query: 274 FLKSLEVSERLKVVDVIGTKVYNDGEQIIAQG 305
+ V E D I K E+I+ G
Sbjct: 168 Y----GVMETGSNNDRIPDKENVPSEKILRAG 195
Score = 72.5 bits (176), Expect = 3e-13, Method: Composition-based stats.
Identities = 32/140 (22%), Positives = 57/140 (40%), Gaps = 13/140 (9%)
Query: 265 YESFIESLPFLKSLEVSERLKVVDVIGTKVY-NDGEQIIAQGDLADSFFIVESGEVKITM 323
Y+ + + L L + + ++ V+ + + G + QG+ S++I+ G V + +
Sbjct: 336 YDELL-HIKALSHLSTTVKRELAGVLIFESHAKGGTVLFNQGEEGTSWYIILKGSVNVVI 394
Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGT-VKCLAMDVQAFERL 382
KG + G FG+LALV + PRAAS L +D + R+
Sbjct: 395 YGKG----------VVCTLHEGDDFGKLALVNDAPRAASIVLREDNCHFLRVDKEDGNRI 444
Query: 383 LGPCMEIMKRNIATYEEQLV 402
L R ++ LV
Sbjct: 445 LRDVEANTVRLKEHDQDVLV 464
Score = 65.6 bits (158), Expect = 3e-11, Method: Composition-based stats.
Identities = 21/114 (18%), Positives = 47/114 (41%), Gaps = 5/114 (4%)
Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
++ + + + ++ + G + QGD+ +++ V +G + + K
Sbjct: 44 LKGVKAFEKFHPNLLRQICLCGYYENLEKGITLFRQGDIGTNWYAVLAGSLDV----KVS 99
Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERL 382
AV I G FGE +++ N PR A+ + + L ++ + F+ L
Sbjct: 100 ETSSHQDAVTICTLGIGTAFGE-SILDNTPRHATIVTRESSELLRIEQEDFKAL 152
>5V4S-A nrPDB
Length = 465
Score = 133 bits (333), Expect = 2e-31, Method: Composition-based stats.
Identities = 33/155 (21%), Positives = 67/155 (43%), Gaps = 17/155 (10%)
Query: 242 LWGLDR---VTFRRIIVKNNA-----KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTK 293
++ +DR ++ K +++ +E +PFLK + + +V +
Sbjct: 305 MYIIDRGWGEDENALLNDLPISLRREVKIQLHRDLLEKVPFLKGADPALVTSLVFSMKPM 364
Query: 294 VYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELAL 353
++ +G+ I +G+ D +I+ G V I + + + GQ+FGELAL
Sbjct: 365 IFLEGDTIFRRGEKGDDLYILSEGSVDIL---------DSDEKTILLSLQEGQFFGELAL 415
Query: 354 VTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCME 388
V + PR+A+ A T + + F+ +L +
Sbjct: 416 VMDAPRSATVRATTTCEIYTLSKTDFDNVLKRFSQ 450
Score = 123 bits (309), Expect = 1e-28, Method: Composition-based stats.
Identities = 39/161 (24%), Positives = 76/161 (47%), Gaps = 12/161 (7%)
Query: 121 DEEEDDAESR--IIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEH 178
E+++A I + + + ++ + + K DP ++ ++ +M + EG+
Sbjct: 312 WGEDENALLNDLPISLRREVKIQLHRDLLEKVPFLKGADPALVTSLVFSMKPMIFLEGDT 371
Query: 179 VIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGN-YDNRGSFGELALMYNTPRAATITAT 237
+ +G+ GD+ Y++ G+ DI D + + FGELAL+ + PR+AT+ AT
Sbjct: 372 IFRRGEKGDDLYILSEGSVDI---LDSDEKTILLSLQEGQFFGELALVMDAPRSATVRAT 428
Query: 238 SPGALWGLDRVTFRRIIVKNNAKKRKMYESFI-ESLPFLKS 277
+ ++ L + F N K+ + S I ES+ LK
Sbjct: 429 TTCEIYTLSKTDF-----DNVLKRFSQFRSAIEESVAHLKK 464
>6CJQ-A nrPDB
Length = 456
Score = 128 bits (322), Expect = 4e-30, Method: Composition-based stats.
Identities = 33/151 (21%), Positives = 60/151 (39%), Gaps = 10/151 (6%)
Query: 259 AKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGE 318
A +++ IE +P K ++ + +Y GE II G++ + + G
Sbjct: 305 AVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIYGPGEYIIRAGEMGSDVYFINRGS 364
Query: 319 VKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQA 378
V++ + A GQ+FGE+AL+ PR A+ A +D +
Sbjct: 365 VEVL---------SADEKTRYAILSEGQFFGEMALILRAPRTATVRARAFCDLYRLDKET 415
Query: 379 FERLLGPCMEIMKRNIATYEEQLVALFGTNM 409
F+R+L EI + I + L + +
Sbjct: 416 FDRILSRYPEIAAQ-IQELAVRRKELESSGL 445
Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats.
Identities = 40/163 (24%), Positives = 69/163 (42%), Gaps = 17/163 (10%)
Query: 120 PDEEEDDAESRIIHPKTDD------QRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLV 173
E E R + + + + + LFK E + ++ + +
Sbjct: 282 LWETRRGYEEREVLKELPHPLRLAVAMEIHGDVIEKVPLFKGAGEEFIRDIILHLEPVIY 341
Query: 174 KEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAAT 233
GE++I G+ G + Y I+RG+ ++ + D R FGE+AL+ PR AT
Sbjct: 342 GPGEYIIRAGEMGSDVYFINRGSVEV-LSADEKTRY-AILSEGQFFGEMALILRAPRTAT 399
Query: 234 ITATSPGALWGLDRVTFRRII---------VKNNAKKRKMYES 267
+ A + L+ LD+ TF RI+ ++ A +RK ES
Sbjct: 400 VRARAFCDLYRLDKETFDRILSRYPEIAAQIQELAVRRKELES 442
>5JON-A nrPDB
Length = 517
Score = 124 bits (311), Expect = 7e-29, Method: Composition-based stats.
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 18/157 (11%)
Query: 250 FRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLAD 309
R IV N +K + S+P + + + ++ + +V+ G+ II +G +
Sbjct: 376 LREEIVNFNCRK------LVASMPLFANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGK 429
Query: 310 SFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTV 369
+ ++ G V + KG E+ + G YFGE+ L+T R AS A
Sbjct: 430 KMYFIQHGVVSVLT--KGNKEM---------KLSDGSYFGEICLLTRGRRTASVRADTYC 478
Query: 370 KCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFG 406
+ ++ V F +L +M+R T + G
Sbjct: 479 RLYSLSVDNFNEVLEEYP-MMRRAFETVAIDRLDRIG 514
Score = 86.0 bits (211), Expect = 3e-17, Method: Composition-based stats.
Identities = 41/229 (17%), Positives = 77/229 (33%), Gaps = 17/229 (7%)
Query: 34 QHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEA 93
+ + ++ A +E D AA KG P S
Sbjct: 289 EGLEAVNKDKPLGAVALKSYEEELAKDPRIAATMENAQKGEIMPNIPQMSAFWYAVRTAV 348
Query: 94 AEAGAFNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLF 153
A + V + AE P EE + ++ + LF
Sbjct: 349 INAASGRQTVDEALKDAQTNAAELNGPLREEIVNFN-------------CRKLVASMPLF 395
Query: 154 KNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNY 213
N DP ++ +L + ++ + G+++I +G G Y I G + K + +
Sbjct: 396 ANADPNFVTAMLTKLKFEVFQPGDYIIREGTIGKKMYFIQHGVVSVLTKGNKEMK----L 451
Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKR 262
+ FGE+ L+ R A++ A + L+ L F ++ + +R
Sbjct: 452 SDGSYFGEICLLTRGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRR 500
>4CHV-A nrPDB
Length = 361
Score = 122 bits (305), Expect = 4e-28, Method: Composition-based stats.
Identities = 30/123 (24%), Positives = 52/123 (42%), Gaps = 13/123 (10%)
Query: 267 SFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRK 326
+ ++P + L + +++V + + G I G+ D F V G V +
Sbjct: 228 QLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVVEGSVSV----- 282
Query: 327 GKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPC 386
VE G +FGE+AL++ +PR+A+ A TV L++ F+ L
Sbjct: 283 -----ATPNPVE---LGPGAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQMLCSSS 334
Query: 387 MEI 389
EI
Sbjct: 335 PEI 337
Score = 109 bits (271), Expect = 3e-24, Method: Composition-based stats.
Identities = 27/120 (22%), Positives = 52/120 (43%), Gaps = 8/120 (6%)
Query: 134 PKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVID 193
+ D RN + + LF+ L P + +++ A+ + V G + G+ GD + +
Sbjct: 219 RRGDFVRN--WQLVAAVPLFQKLGPAVLVEIVRALRARTVPAGAVICRIGEPGDRMFFVV 276
Query: 194 RGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRI 253
G+ + FGE+AL+ PR+AT++A + +L L F+ +
Sbjct: 277 EGSVSVATPN------PVELGPGAFFGEMALISGEPRSATVSAATTVSLLSLHSADFQML 330
>5U6P-A nrPDB
Length = 660
Score = 119 bits (299), Expect = 2e-27, Method: Composition-based stats.
Identities = 32/166 (19%), Positives = 63/166 (37%), Gaps = 18/166 (10%)
Query: 247 RVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGD 306
R IV N +K + ++P + + + ++ + +V+ G+ II +G
Sbjct: 454 NDPLREEIVNFNCRK------LVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGA 507
Query: 307 LADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAI 366
+ + ++ G + K + + G YFGE+ L+T R AS A
Sbjct: 508 VGKKMYFIQHGVAGVITKSSKEM-----------KLTDGSYFGEICLLTKGRRTASVRAD 556
Query: 367 GTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQLVALFGTNMDIV 412
+ ++ V F +L +M+R T + G I+
Sbjct: 557 TYCRLYSLSVDNFNEVLEEYP-MMRRAFETVAIDRLDRIGKKNSIL 601
Score = 81.8 bits (200), Expect = 5e-16, Method: Composition-based stats.
Identities = 34/162 (20%), Positives = 68/162 (41%), Gaps = 5/162 (3%)
Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
++ + LF N DP ++ +L + ++ + G+++I +G G Y I G + K
Sbjct: 467 RKLVATMPLFANADPNFVTAMLSKLRFEVFQPGDYIIREGAVGKKMYFIQHGVAGVITKS 526
Query: 204 DGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 263
+ + FGE+ L+ R A++ A + L+ L F ++ + +R
Sbjct: 527 SKEMK----LTDGSYFGEICLLTKGRRTASVRADTYCRLYSLSVDNFNEVLEEYPMMRRA 582
Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGE-QIIAQ 304
I+ L + K + T V+N+ E +I+ Q
Sbjct: 583 FETVAIDRLDRIGKKNSILLQKFQKDLNTGVFNNQENEILKQ 624
>3DKW-A nrPDB
Length = 227
Score = 117 bits (292), Expect = 1e-26, Method: Composition-based stats.
Identities = 29/117 (24%), Positives = 52/117 (44%), Gaps = 2/117 (1%)
Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VK 202
Q+ + LF+ L P Q+ ++L + + +G +V QG+ FY + G IY +
Sbjct: 8 QQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIYRLT 67
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKNN 258
+G + + + R +F E + +TP AT A P L+ + R + N
Sbjct: 68 PEGQEKILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLRQLQDNT 124
Score = 53.3 bits (126), Expect = 2e-07, Method: Composition-based stats.
Identities = 22/122 (18%), Positives = 47/122 (38%), Gaps = 7/122 (5%)
Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
++++ ++S + L + +++ + G + QG+ A +F+ + SG VKI
Sbjct: 5 RVHQQLLQSHHLFEPLSPVQLQELLASSDLVNLDKGAYVFRQGEPAHAFYYLISGCVKIY 64
Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPR-AASAHAIGTVKCLAMDVQAFER 381
E + F E + + P A+A A+ + +A+ R
Sbjct: 65 RLTPEGQE------KILEVTNERNTFAEAMMFMDTPNYVATAQAVVPSQLFRFSNKAYLR 118
Query: 382 LL 383
L
Sbjct: 119 QL 120
>4EV0-A nrPDB
Length = 216
Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats.
Identities = 28/118 (23%), Positives = 47/118 (39%), Gaps = 1/118 (0%)
Query: 147 CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDG 205
K LF L PE++ L +L +G+ + QGD G Y++ G ++ G
Sbjct: 1 MKGSPLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGG 60
Query: 206 VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRK 263
R + FGE++L+ R+A+ A L L R + +I +
Sbjct: 61 QERTLALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALIRRLPLVAHN 118
Score = 92.9 bits (229), Expect = 2e-19, Method: Composition-based stats.
Identities = 30/119 (25%), Positives = 53/119 (44%), Gaps = 6/119 (5%)
Query: 273 PFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVE 332
P L E + ++Y G+ I QGDL + ++V SG+V++ G E
Sbjct: 5 PLFHGLAPEEVDLALSYFQRRLYPQGKPIFYQGDLGQALYLVASGKVRLFRTHLGGQE-- 62
Query: 333 ENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMK 391
+A G+ FGE++L+ R+ASA A+ + LA+ + + L+ +
Sbjct: 63 ----RTLALLGPGELFGEMSLLDEGERSASAVAVEDTELLALFREDYLALIRRLPLVAH 117
>4ORF-A nrPDB
Length = 340
Score = 85.6 bits (210), Expect = 3e-17, Method: Composition-based stats.
Identities = 29/115 (25%), Positives = 49/115 (42%), Gaps = 7/115 (6%)
Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
+ +L F S + + G+ +I QGD A +F ++ESG V++
Sbjct: 19 LAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFMLIESGRVQV------- 71
Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLL 383
S +G + G GE+AL+ + P+ A+ A V D AF+ +L
Sbjct: 72 SHAVADGPPIVLDIEPGLIIGEIALLRDAPKTATVVAAEPVIGWVGDRDAFDTIL 126
Score = 77.5 bits (189), Expect = 1e-14, Method: Composition-based stats.
Identities = 32/160 (20%), Positives = 55/160 (34%), Gaps = 10/160 (6%)
Query: 136 TDDQRNRLQEA----CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYV 191
L E + F P + + + + G+ +I QGD F +
Sbjct: 4 DPGNVAELTEVRAADLAALEFFTGCRPSALEPLATQLRPLKAEPGQVLIRQGDPALTFML 63
Query: 192 IDRGTFDIYVKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFR 251
I+ G + V + + GE+AL+ + P+ AT+ A P W DR F
Sbjct: 64 IESGRVQVSHAVADGPPIVLDIEPGLIIGEIALLRDAPKTATVVAAEPVIGWVGDRDAFD 123
Query: 252 RIIV------KNNAKKRKMYESFIESLPFLKSLEVSERLK 285
I+ + R+ +FI +P L+
Sbjct: 124 TILHLPGMFDRLVRIARQRLAAFITPIPVQVRTGEWFYLR 163
>4CYD-A nrPDB
Length = 225
Score = 84.9 bits (208), Expect = 6e-17, Method: Composition-based stats.
Identities = 23/115 (20%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
+QE +F+ +DP ++ ++ M G + D+G+ GD Y+I G +
Sbjct: 2 VQEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLARH 61
Query: 203 -CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
DG + FGEL++ PR ++ + ++ R +
Sbjct: 62 APDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVAD 116
Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats.
Identities = 21/124 (16%), Positives = 45/124 (36%), Gaps = 6/124 (4%)
Query: 266 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKR 325
+ + + ++ + ++ + T + G I +G+ D +I+ SG+VK+
Sbjct: 3 QEILSRAGIFQGVDPTAVNNLIQDMETVRFPRGATIFDEGEPGDRLYIITSGKVKLAR-- 60
Query: 326 KGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGP 385
+ + FGEL++ PR +SA + V M+ +
Sbjct: 61 ----HAPDGRENLLTIMGPSDMFGELSIFDPGPRTSSAVCVTEVHAATMNSDMLRNWVAD 116
Query: 386 CMEI 389
I
Sbjct: 117 HPAI 120
>3I59-A nrPDB
Length = 249
Score = 84.5 bits (207), Expect = 7e-17, Method: Composition-based stats.
Identities = 25/115 (21%), Positives = 45/115 (39%), Gaps = 1/115 (0%)
Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
+ E +F+ ++P ++ + + G V +G+ GD Y+I G I +
Sbjct: 26 MDEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRR 85
Query: 203 -CDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
DG + FGEL++ PR ++ T + +DR R I
Sbjct: 86 APDGRENLLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIAD 140
Score = 82.9 bits (203), Expect = 2e-16, Method: Composition-based stats.
Identities = 28/124 (22%), Positives = 50/124 (40%), Gaps = 6/124 (4%)
Query: 266 ESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKR 325
+ + + +E S + + + G + A+G+ D +I+ SG+VKI +
Sbjct: 27 DEILARAGIFQGVEPSAIAALTKQLQPVDFPRGHTVFAEGEPGDRLYIIISGKVKIGRRA 86
Query: 326 KGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGP 385
E + FGEL++ PR +SA I V+ ++MD A +
Sbjct: 87 PDGREN------LLTIMGPSDMFGELSIFDPGPRTSSATTITEVRAVSMDRDALRSWIAD 140
Query: 386 CMEI 389
EI
Sbjct: 141 RPEI 144
>4AVC-A nrPDB
Length = 333
Score = 81.4 bits (199), Expect = 6e-16, Method: Composition-based stats.
Identities = 25/111 (22%), Positives = 47/111 (42%), Gaps = 7/111 (6%)
Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
+ + + + + + G+ ++ QG+ A SF ++ SG ++
Sbjct: 15 LAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEV------- 67
Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAF 379
S V ++G IAR G GE+AL+ + PR+A+ I + AF
Sbjct: 68 SHVGDDGVAIIARALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAF 118
Score = 72.1 bits (175), Expect = 4e-13, Method: Composition-based stats.
Identities = 26/136 (19%), Positives = 56/136 (41%), Gaps = 6/136 (4%)
Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
E + +F+ E + + ++ G+ ++ QG+ +F +I G+ ++ D
Sbjct: 13 EDLAGMDVFQGCPAEGLVSLAASVQPLRAAAGQVLLRQGEPAVSFLLISSGSAEVSHVGD 72
Query: 205 GVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRII------VKNN 258
+ GE+AL+ ++PR+AT+T P W R F ++ +
Sbjct: 73 DGVAIIARALPGMIVGEIALLRDSPRSATVTTIEPLTGWTGGRGAFATMVHIPGVGERLL 132
Query: 259 AKKRKMYESFIESLPF 274
R+ +F+ +P
Sbjct: 133 RTARQRLAAFVSPIPV 148
>5XBY-A nrPDB
Length = 97
Score = 80.2 bits (196), Expect = 2e-15, Method: Composition-based stats.
Identities = 28/50 (56%), Positives = 38/50 (76%)
Query: 4 EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGH 53
+IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL++ ++ F
Sbjct: 5 QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLREARNKEQQNAFYE 54
>5H78-A nrPDB
Length = 197
Score = 79.5 bits (194), Expect = 2e-15, Method: Composition-based stats.
Identities = 29/60 (48%), Positives = 41/60 (68%)
Query: 3 IEIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAG 62
++IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+ E + + + + D
Sbjct: 4 MQIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRSERVNERVKQLAEKAKEATDKE 63
>5H77-A nrPDB
Length = 90
Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats.
Identities = 33/82 (40%), Positives = 47/82 (57%)
Query: 4 EIPAGLTELLQGFTVEVLRHQPADLLEFALQHFTRLQQENERKGAARFGHEGRTWGDAGA 63
+IP GLTELLQG+TVEVLR QP DL+EFA+++FTRL+Q+ + +A
Sbjct: 5 QIPPGLTELLQGYTVEVLRQQPPDLVEFAVEYFTRLRQQRAFYEILHLPNLNEEQRNAFI 64
Query: 64 AAGGGIPSKGVNFAEEPMRSDS 85
+ PS+ N E + +
Sbjct: 65 QSLKDDPSQSANLLAEAKKLND 86
>5H3O-A nrPDB
Length = 738
Score = 76.8 bits (187), Expect = 2e-14, Method: Composition-based stats.
Identities = 22/135 (16%), Positives = 53/135 (39%), Gaps = 15/135 (11%)
Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKIT 322
+++ + + + E ++V + +V++ G+ I +GD+ +IV+ G +++
Sbjct: 487 QVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQV- 545
Query: 323 MKRKGKSEVEENGAVEIARCFRGQYFGELALV------TNKPRAASAHAIGTVKCLAMDV 376
V+++G G FGEL+++ R A+ ++G +
Sbjct: 546 --------VDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSK 597
Query: 377 QAFERLLGPCMEIMK 391
L + K
Sbjct: 598 TDLWNALREYPDARK 612
Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats.
Identities = 21/151 (13%), Positives = 57/151 (37%), Gaps = 11/151 (7%)
Query: 145 EACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCD 204
E + + +F++ + +++++ + ++ G+ + +GD G Y++ RG + D
Sbjct: 491 ETLRKVRIFQDCEAGLLAELVLKLQLQVFSPGDFICKKGDIGREMYIVKRGRLQVV--DD 548
Query: 205 GVGRCVGNYDNRGSFGELALM------YNTPRAATITATSPGALWGLDRVTFRRIIVKNN 258
+ FGEL+++ R A + + L+ L + + +
Sbjct: 549 DGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSVGYTDLFVLSKTDLWNALREYP 608
Query: 259 AKKRKMY---ESFIESLPFLKSLEVSERLKV 286
++ + ++ L E+ V
Sbjct: 609 DARKLLLAKGREILKKDNLLDENAPEEQKTV 639
>4I0B-A nrPDB
Length = 222
Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats.
Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 7/113 (6%)
Query: 290 IGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFG 349
Y +I QG+ A++ + + G V + +K + E+ ++ +G + G
Sbjct: 31 CHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEM------ILSYLNQGDFIG 84
Query: 350 ELALVTNK-PRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
EL L R+A A + + + F +L+ +I+ R A +L
Sbjct: 85 ELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRL 137
Score = 63.3 bits (152), Expect = 2e-10, Method: Composition-based stats.
Identities = 29/152 (19%), Positives = 56/152 (36%), Gaps = 15/152 (9%)
Query: 173 VKEGEHVIDQGDDGDNFYVIDRGTFDIYVK-CDGVGRCVGNYDNRGSFGELALMYNTP-R 230
+I QG+ + Y I +G+ + +K +G + + GEL L R
Sbjct: 36 YPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEGQER 95
Query: 231 AATITATSPGALWGLDRVTFRRIIVKN----------NAKKRKMYESFIESLPFLKSLE- 279
+A + A + + + FR++I N A++ ++ + +L FL
Sbjct: 96 SAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRLQVTSEKVGNLAFLDVTGR 155
Query: 280 -VSERLKVVDVIGTKVYNDGEQI-IAQGDLAD 309
L + DG QI I + ++
Sbjct: 156 IAQTLLNLAKQPDAMTLPDGMQIKITRQEIGQ 187
>3KCC-A nrPDB
Length = 260
Score = 73.7 bits (179), Expect = 1e-13, Method: Composition-based stats.
Identities = 23/113 (20%), Positives = 46/113 (40%), Gaps = 7/113 (6%)
Query: 290 IGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFG 349
Y +I QG+ A++ + + G V + +K + E+ ++ +G + G
Sbjct: 69 CHIHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEM------ILSYLNQGDFIG 122
Query: 350 ELALVTNK-PRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATYEEQL 401
EL L R+A A + + + F +L+ +I+ R A +L
Sbjct: 123 ELGLFEEGQERSAWVRAKTACEVAEISYKKFRQLIQVNPDILMRLSAQMARRL 175
Score = 64.4 bits (155), Expect = 8e-11, Method: Composition-based stats.
Identities = 27/148 (18%), Positives = 51/148 (34%), Gaps = 5/148 (3%)
Query: 110 RASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQVLDAMF 169
R S E E +S + D ++ ++L K + L
Sbjct: 14 RGSGMKETAAAKFERQHMDSPDL---GTDDDDKAMADIGSMVLGKPQTDPTLEWFLSHCH 70
Query: 170 EKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK-CDGVGRCVGNYDNRGSFGELALMYNT 228
+I QG+ + Y I +G+ + +K +G + + GEL L
Sbjct: 71 IHKYPSKSTLIHQGEKAETLYYIVKGSVAVLIKDEEGKEMILSYLNQGDFIGELGLFEEG 130
Query: 229 P-RAATITATSPGALWGLDRVTFRRIIV 255
R+A + A + + + FR++I
Sbjct: 131 QERSAWVRAKTACEVAEISYKKFRQLIQ 158
>3E97-A nrPDB
Length = 231
Score = 72.5 bits (176), Expect = 3e-13, Method: Composition-based stats.
Identities = 30/149 (20%), Positives = 66/149 (44%), Gaps = 14/149 (9%)
Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
++ P +++ + + V+ + + E ++ Q ++ +V +G V+++ G
Sbjct: 8 LKRSPLFQNVPEDAMREALKVVTERNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGG 67
Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFE-------R 381
E G GE A++ ++ R+AS A+ V+ L + + FE R
Sbjct: 68 RERVLGD-----IYAPG-VVGETAVLAHQERSASVRALTPVRTLMLHREHFELILRRHPR 121
Query: 382 LLGPCMEIMKRNIATYEEQLVALFGTNMD 410
+L E++ R + ++L+A FG N +
Sbjct: 122 VLWNLAEMLARRVTFLNDELIA-FGQNTE 149
Score = 72.5 bits (176), Expect = 3e-13, Method: Composition-based stats.
Identities = 31/132 (23%), Positives = 60/132 (45%), Gaps = 1/132 (0%)
Query: 147 CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDG 205
K LF+N+ + M + L + E+ + E V++Q +G+ +++ G + V G
Sbjct: 8 LKRSPLFQNVPEDAMREALKVVTERNFQPDELVVEQDAEGEALHLVTTGVVRVSRVSLGG 67
Query: 206 VGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMY 265
R +G+ G GE A++ + R+A++ A +P L R F I+ ++ +
Sbjct: 68 RERVLGDIYAPGVVGETAVLAHQERSASVRALTPVRTLMLHREHFELILRRHPRVLWNLA 127
Query: 266 ESFIESLPFLKS 277
E + FL
Sbjct: 128 EMLARRVTFLND 139
>5W5B-A nrPDB
Length = 236
Score = 66.0 bits (159), Expect = 3e-11, Method: Composition-based stats.
Identities = 26/125 (20%), Positives = 53/125 (42%), Gaps = 7/125 (5%)
Query: 278 LEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAV 337
L + + + + K + G + AD +IV G +++ + + + V
Sbjct: 37 LHRDDVSALAETLQVKEFAPGAVVFHADQTADGVWIVRHGLIELAVGSRRRRAV------ 90
Query: 338 EIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIMKRNIATY 397
+ G G++ L+ P + A+ CL +D QAFERLL I +R +++
Sbjct: 91 -VNILHPGDVDGDIPLLLEMPMVYTGRALTQATCLFLDRQAFERLLATHPAIARRWLSSV 149
Query: 398 EEQLV 402
+++
Sbjct: 150 AQRVS 154
>5VA1-A nrPDB
Length = 795
Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats.
Identities = 17/127 (13%), Positives = 39/127 (30%), Gaps = 13/127 (10%)
Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM 323
+ S ++ + + T G+ ++ GDL + + + G ++I
Sbjct: 492 LNRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILR 551
Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAAS--AHAIGTVKCLAMDVQAFER 381
V +A + FGE + +P ++ A+ +
Sbjct: 552 GD-----------VVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLE 600
Query: 382 LLGPCME 388
+L E
Sbjct: 601 VLDMYPE 607
Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats.
Identities = 18/113 (15%), Positives = 35/113 (30%), Gaps = 6/113 (5%)
Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
+ + F+ + + G+ ++ GD Y I RG+ +I
Sbjct: 494 RSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG- 552
Query: 204 DGVGRCVGNYDNRGSFGELALMYNTPRAAT--ITATSPGALWGLDRVTFRRII 254
V FGE +Y P + + A + L + R ++
Sbjct: 553 ---DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVL 602
>2N7G-A nrPDB
Length = 154
Score = 62.9 bits (151), Expect = 3e-10, Method: Composition-based stats.
Identities = 17/135 (12%), Positives = 39/135 (28%), Gaps = 13/135 (9%)
Query: 256 KNNAKKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVE 315
+ S ++ + + T G+ ++ GDL + + +
Sbjct: 14 GTENLYFQSMRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFIS 73
Query: 316 SGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAAS--AHAIGTVKCLA 373
G ++I V +A + FGE + +P ++ A+
Sbjct: 74 RGSIEILRGD-----------VVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHK 122
Query: 374 MDVQAFERLLGPCME 388
+ +L E
Sbjct: 123 IHRDDLLEVLDMYPE 137
Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats.
Identities = 18/114 (15%), Positives = 36/114 (31%), Gaps = 6/114 (5%)
Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
++ + F+ + + G+ ++ GD Y I RG+ +I
Sbjct: 23 MRSLLQHCKPFRGATKGCLRALAMKFKTTHAPPGDTLVHAGDLLTALYFISRGSIEILRG 82
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTPRAAT--ITATSPGALWGLDRVTFRRII 254
V FGE +Y P + + A + L + R ++
Sbjct: 83 ----DVVVAILGKNDIFGEPLNLYARPGKSNGDVRALTYCDLHKIHRDDLLEVL 132
>2OZ6-A nrPDB
Length = 207
Score = 62.1 bits (149), Expect = 4e-10, Method: Composition-based stats.
Identities = 25/110 (22%), Positives = 41/110 (37%), Gaps = 10/110 (9%)
Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
K++ + Y II GD ++ F + G V I ++ E+ I
Sbjct: 8 KLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREM------IIGYLNS 61
Query: 345 GQYFGELALV----TNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEIM 390
G +FGEL L + + R+A A + + F L EI+
Sbjct: 62 GDFFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQDSEIL 111
Score = 61.4 bits (147), Expect = 7e-10, Method: Composition-based stats.
Identities = 20/103 (19%), Positives = 41/103 (39%), Gaps = 5/103 (4%)
Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK-CDGVGRCVGNYDNRG 217
+ + ++L + +I GD + + I +G+ I ++ DG +G ++
Sbjct: 4 KHLDKLLAHCHRRRYTAKSTIIYAGDRCETLFFIIKGSVTILIEDDDGREMIIGYLNSGD 63
Query: 218 SFGELALM----YNTPRAATITATSPGALWGLDRVTFRRIIVK 256
FGEL L R+A + A + + FR + +
Sbjct: 64 FFGELGLFEKEGSEQERSAWVRAKVECEVAEISYAKFRELSQQ 106
>3H3Z-A nrPDB
Length = 235
Score = 60.6 bits (145), Expect = 1e-09, Method: Composition-based stats.
Identities = 21/118 (17%), Positives = 46/118 (38%), Gaps = 1/118 (0%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI 199
+ ++ LL ++L + + +L + GE + Q + +V+ G +
Sbjct: 4 HEAQKAIARNSLLIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKL 63
Query: 200 Y-VKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVK 256
+ + G V + SFGE + NTP + A +P + + F ++ +
Sbjct: 64 FRMTPTGSEAVVSVFTRGESFGEAVALRNTPYPVSAEAVTPCEVMHIPSPVFVSLMRR 121
Score = 56.4 bits (134), Expect = 2e-08, Method: Composition-based stats.
Identities = 27/116 (23%), Positives = 47/116 (40%), Gaps = 6/116 (5%)
Query: 274 FLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEE 333
++SL ++ + Y+ GE + Q + A + +V G VK+ SE
Sbjct: 16 LIRSLPEQHVDALLSQAVWRSYDRGETLFLQEEKAQAIHVVIDGWVKLFRMTPTGSE--- 72
Query: 334 NGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDVQAFERLLGPCMEI 389
++ RG+ FGE + N P SA A+ + + + F L+ EI
Sbjct: 73 ---AVVSVFTRGESFGEAVALRNTPYPVSAEAVTPCEVMHIPSPVFVSLMRRDPEI 125
>3UKN-A nrPDB
Length = 212
Score = 59.4 bits (142), Expect = 2e-09, Method: Composition-based stats.
Identities = 23/136 (16%), Positives = 48/136 (35%), Gaps = 13/136 (9%)
Query: 269 IESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGK 328
+ LP +S + +I T GE +I QGD + + V SG +++
Sbjct: 77 LLQLPLFESASRGCLRSLSLIIKTSFCAPGEFLIRQGDALQAIYFVCSGSMEVLKDN--- 133
Query: 329 SEVEENGAVEIARCFRGQYFGELALVTNKP--RAASAHAIGTVKCLAMDVQAFERLLGPC 386
+A +G G +L + A+ A+ + ++ +L
Sbjct: 134 --------TVLAILGKGDLIGSDSLTKEQVIKTNANVKALTYCDLQYISLKGLREVLRLY 185
Query: 387 MEIMKRNIATYEEQLV 402
E ++ ++ + L
Sbjct: 186 PEYAQKFVSEIQHDLT 201
Score = 46.7 bits (109), Expect = 2e-05, Method: Composition-based stats.
Identities = 17/115 (14%), Positives = 36/115 (31%), Gaps = 6/115 (5%)
Query: 143 LQEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVK 202
L + + LF++ + + + GE +I QGD Y + G+ ++
Sbjct: 73 LNKELLQLPLFESASRGCLRSLSLIIKTSFCAPGEFLIRQGDALQAIYFVCSGSMEVLK- 131
Query: 203 CDGVGRCVGNYDNRGSFGELALMYNTP--RAATITATSPGALWGLDRVTFRRIIV 255
+ G +L A + A + L + R ++
Sbjct: 132 ---DNTVLAILGKGDLIGSDSLTKEQVIKTNANVKALTYCDLQYISLKGLREVLR 183
>5K7L-A nrPDB
Length = 857
Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats.
Identities = 17/131 (12%), Positives = 39/131 (29%), Gaps = 12/131 (9%)
Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
++ K+ F+ + + G+ + G+ D+ + G+ ++
Sbjct: 546 RKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ-- 603
Query: 204 DGVGRCVGNYDNRGSFG-----ELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNN 258
V FG E L A + A + L + R ++++
Sbjct: 604 --DDEVVAILGKGDVFGDVFWKEATL---AQSCANVRALTYCDLHVIKRDALQKVLEFYT 658
Query: 259 AKKRKMYESFI 269
A + I
Sbjct: 659 AFSHSFSRNLI 669
Score = 51.3 bits (121), Expect = 7e-07, Method: Composition-based stats.
Identities = 25/150 (16%), Positives = 48/150 (32%), Gaps = 21/150 (14%)
Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM 323
+ + P + + T G+ I G+ DS V SG +++
Sbjct: 544 LNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ 603
Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGEL----ALVTNKPRAASAHAIGTVKCLAMDVQAF 379
+ +A +G FG++ A + A+ A+ + A
Sbjct: 604 DDEV-----------VAILGKGDVFGDVFWKEATLAQS--CANVRALTYCDLHVIKRDAL 650
Query: 380 ERLL---GPCMEIMKRN-IATYEEQLVALF 405
+++L RN I TY + +F
Sbjct: 651 QKVLEFYTAFSHSFSRNLILTYNLRKRIVF 680
>4F8A-A nrPDB
Length = 160
Score = 56.4 bits (134), Expect = 3e-08, Method: Composition-based stats.
Identities = 17/131 (12%), Positives = 39/131 (29%), Gaps = 12/131 (9%)
Query: 144 QEACKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC 203
++ K+ F+ + + G+ + G+ D+ + G+ ++
Sbjct: 26 RKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ-- 83
Query: 204 DGVGRCVGNYDNRGSFG-----ELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNN 258
V FG E L A + A + L + R ++++
Sbjct: 84 --DDEVVAILGKGDVFGDVFWKEATL---AQSCANVRALTYCDLHVIKRDALQKVLEFYT 138
Query: 259 AKKRKMYESFI 269
A + I
Sbjct: 139 AFSHSFSRNLI 149
Score = 51.3 bits (121), Expect = 7e-07, Method: Composition-based stats.
Identities = 25/150 (16%), Positives = 48/150 (32%), Gaps = 21/150 (14%)
Query: 264 MYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITM 323
+ + P + + T G+ I G+ DS V SG +++
Sbjct: 24 LNRKVFKEHPAFRLASDGCLRALAMEFQTVHCAPGDLIYHAGESVDSLCFVVSGSLEVIQ 83
Query: 324 KRKGKSEVEENGAVEIARCFRGQYFGEL----ALVTNKPRAASAHAIGTVKCLAMDVQAF 379
+ +A +G FG++ A + A+ A+ + A
Sbjct: 84 DDEV-----------VAILGKGDVFGDVFWKEATLAQS--CANVRALTYCDLHVIKRDAL 130
Query: 380 ERLL---GPCMEIMKRN-IATYEEQLVALF 405
+++L RN I TY + +F
Sbjct: 131 QKVLEFYTAFSHSFSRNLILTYNLRKRIVF 160
>3IWZ-A nrPDB
Length = 230
Score = 52.5 bits (124), Expect = 4e-07, Method: Composition-based stats.
Identities = 16/103 (15%), Positives = 32/103 (31%), Gaps = 2/103 (1%)
Query: 155 NLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGV-GRCVGNY 213
LD + + L + V GD Y + G+ I + D +G +
Sbjct: 21 TLDAGTIERFLAHSHRRRYPTRTDVFRPGDPAGTLYYVISGSVSIIAEEDDDRELVLGYF 80
Query: 214 DNRGSFGELALMYN-TPRAATITATSPGALWGLDRVTFRRIIV 255
+ GE+ L R + + L + +++
Sbjct: 81 GSGEFVGEMGLFIESDTREVILRTRTQCELAEISYERLQQLFQ 123
Score = 46.0 bits (107), Expect = 3e-05, Method: Composition-based stats.
Identities = 16/91 (17%), Positives = 36/91 (39%), Gaps = 7/91 (7%)
Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
+ Y + GD A + + V SG V I +E +++ + + G++ GE+
Sbjct: 37 RRYPTRTDVFRPGDPAGTLYYVISGSVSII------AEEDDDRELVLGYFGSGEFVGEMG 90
Query: 353 L-VTNKPRAASAHAIGTVKCLAMDVQAFERL 382
L + + R + + + ++L
Sbjct: 91 LFIESDTREVILRTRTQCELAEISYERLQQL 121
>4L11-A nrPDB
Length = 204
Score = 51.7 bits (122), Expect = 5e-07, Method: Composition-based stats.
Identities = 23/132 (17%), Positives = 47/132 (35%), Gaps = 10/132 (7%)
Query: 153 FKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGN 212
F+ P + + G+ ++ +GD Y I RG+ +I +
Sbjct: 80 FEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIARGSIEILK----DDVVMAI 135
Query: 213 YDNRGSFGELALMYNT--PRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIE 270
FGE +++T + + A + L + R ++ + Y+SF+
Sbjct: 136 LGKDDIFGENPCIHSTLGKSNSNVKALTYCDLHKIHRDDLLDVLDLFP----EFYDSFVN 191
Query: 271 SLPFLKSLEVSE 282
SL ++ E
Sbjct: 192 SLEITYNMRDEE 203
Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats.
Identities = 12/106 (11%), Positives = 32/106 (30%), Gaps = 13/106 (12%)
Query: 273 PFLKSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVE 332
++ + T G+ ++ +GD+ + + G ++I
Sbjct: 78 SAFEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIARGSIEILKDD------- 130
Query: 333 ENGAVEIARCFRGQYFGELALVTN--KPRAASAHAIGTVKCLAMDV 376
V +A + FGE + + ++ A+ +
Sbjct: 131 ----VVMAILGKDDIFGENPCIHSTLGKSNSNVKALTYCDLHKIHR 172
>2D93-A nrPDB
Length = 134
Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats.
Identities = 27/120 (22%), Positives = 47/120 (39%), Gaps = 14/120 (11%)
Query: 141 NRLQEACKDILLFKNLDPEQMSQVLDAM-FEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI 199
+L E + F N+ ++ M FE + + G +++ G + D++YVI GT +I
Sbjct: 12 EQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVILNGTVEI 71
Query: 200 YVKCDGVGRCVGNYDNRGSFG-----ELALMYNTPRAATITATSPGALWGLDRVTFRRII 254
DG V N SFG + M+ R + + + RI+
Sbjct: 72 S-HPDGK---VENLFMGNSFGITPTLDKQYMHGIVRT----KVDDCQFVCIAQQDYWRIL 123
Score = 42.9 bits (99), Expect = 3e-04, Method: Composition-based stats.
Identities = 22/128 (17%), Positives = 49/128 (38%), Gaps = 13/128 (10%)
Query: 262 RKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYND-GEQIIAQGDLADSFFIVESGEVK 320
+ F+ LP ++ +S R ++ V+ +V G I+ G DS++++ +G V+
Sbjct: 11 IEQLLEFMHQLPAFANMTMSVRRELCSVMIFEVVEQAGAIILEDGQELDSWYVILNGTVE 70
Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHA-IGTVKCLAMDVQAF 379
I + ++ F G FG + + + + + + Q +
Sbjct: 71 I-----------SHPDGKVENLFMGNSFGITPTLDKQYMHGIVRTKVDDCQFVCIAQQDY 119
Query: 380 ERLLGPCM 387
R+L
Sbjct: 120 WRILNHVE 127
>3B02-A nrPDB
Length = 195
Score = 47.1 bits (110), Expect = 1e-05, Method: Composition-based stats.
Identities = 30/113 (26%), Positives = 47/113 (41%), Gaps = 11/113 (9%)
Query: 293 KVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELA 352
K + E I +G+ A + + +E G V++ + + + + G YFGE A
Sbjct: 2 KRFARKETIYLRGEEARTLYRLEEGLVRVV------ELLPDGRLITLRHVLPGDYFGEEA 55
Query: 353 LVTNKPR-AASAHAIGTVKCL---AMDVQAFERLLGPCMEIMKRNIATYEEQL 401
L R A A V+ L AMD +A R+ M+R + YE L
Sbjct: 56 LEGKAYRYTAEAMTEAVVQGLEPRAMDHEALHRVARNLARQMRR-VQAYEAHL 107
Score = 37.9 bits (86), Expect = 0.008, Method: Composition-based stats.
Identities = 18/108 (16%), Positives = 38/108 (35%), Gaps = 7/108 (6%)
Query: 171 KLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELALMYNTP 229
K E + +G++ Y ++ G + + DG + + FGE AL
Sbjct: 2 KRFARKETIYLRGEEARTLYRLEEGLVRVVELLPDGRLITLRHVLPGDYFGEEALEGKAY 61
Query: 230 R-AATITATSPGALW---GLDRVTFRRIIVKNN--AKKRKMYESFIES 271
R A + +D R+ ++ + YE+ +++
Sbjct: 62 RYTAEAMTEAVVQGLEPRAMDHEALHRVARNLARQMRRVQAYEAHLQT 109
>2XKO-A nrPDB
Length = 222
Score = 46.3 bits (108), Expect = 2e-05, Method: Composition-based stats.
Identities = 16/81 (19%), Positives = 32/81 (39%), Gaps = 3/81 (3%)
Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCVGNYDNRGSFGELALMY 226
+ + + G+ + GD + Y++ +G + V G V FG L+L+
Sbjct: 22 LQIEQFERGKTIFFPGDPAERVYLLVKGAVKLSRVYESGEEITVALLRENSVFGVLSLLT 81
Query: 227 N--TPRAATITATSPGALWGL 245
+ R A +P L+ +
Sbjct: 82 GQRSDRFYHAVAFTPVQLFSV 102
>3LA7-A nrPDB
Length = 243
Score = 45.6 bits (106), Expect = 4e-05, Method: Composition-based stats.
Identities = 26/121 (21%), Positives = 49/121 (40%), Gaps = 11/121 (9%)
Query: 292 TKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGEL 351
+ + + I GD A+ + + G VK++ + E + +A FG L
Sbjct: 45 VETFERNKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEE------ITVALLRENSVFGVL 98
Query: 352 ALVTNKP--RAASAHAIGTVKCLAMDVQAFERLLGPCME---IMKRNIATYEEQLVALFG 406
+L+T R A A V+ L+ ++ E+ L E +M R +++ Q +
Sbjct: 99 SLLTGNKSDRFYHAVAFTPVELLSAPIEQVEQALKENPELSMLMLRGLSSRILQTEMMIE 158
Query: 407 T 407
T
Sbjct: 159 T 159
Score = 44.4 bits (103), Expect = 8e-05, Method: Composition-based stats.
Identities = 18/96 (18%), Positives = 29/96 (30%), Gaps = 5/96 (5%)
Query: 154 KNLDPEQMSQVLDAMFEK--LVKEGEHVIDQGDDGDNFYVIDRGTFDIY-VKCDGVGRCV 210
K L A + + + GD + Y + +G + V G V
Sbjct: 27 KALANVFRQMATGAFPPVVETFERNKTIFFPGDPAERVYFLLKGAVKLSRVYEAGEEITV 86
Query: 211 GNYDNRGSFGELALM--YNTPRAATITATSPGALWG 244
FG L+L+ + R A +P L
Sbjct: 87 ALLRENSVFGVLSLLTGNKSDRFYHAVAFTPVELLS 122
>1ZYB-A nrPDB
Length = 232
Score = 45.2 bits (105), Expect = 5e-05, Method: Composition-based stats.
Identities = 24/141 (17%), Positives = 43/141 (30%), Gaps = 19/141 (13%)
Query: 140 RNRLQEACKDILLFKNLDPEQMSQVLDA--MFEKLVKEGEHVIDQGDDGDNFYVIDRGTF 197
+ + + LF+ L E + +LD + K GE +I G+ + +G
Sbjct: 13 METMFDTLLQLPLFQGLCHEDFTSILDKVKLHFIKHKAGETIIKSGNPCTQLCFLLKGEI 72
Query: 198 DIYVKCDGVGRCVGN-------YDNRGSFGELALMYNTPRAATITATSPGALWGLDR--- 247
I V + + FG NT A++ A + + +
Sbjct: 73 SIVTNAKENIYTVIEQIEAPYLIEPQSLFG-----MNTNYASSYVAHTEVHTVCISKAFV 127
Query: 248 --VTFRRIIVKNNAKKRKMYE 266
FR I + N
Sbjct: 128 LSDLFRYDIFRLNYMNIVSNR 148
Score = 41.3 bits (95), Expect = 7e-04, Method: Composition-based stats.
Identities = 21/116 (18%), Positives = 38/116 (32%), Gaps = 8/116 (6%)
Query: 263 KMYESFIESLPFLKSLEVSERLKVVDVIG--TKVYNDGEQIIAQGDLADSFFIVESGEVK 320
M+++ ++ LP + L + ++D + + GE II G+ + GE+
Sbjct: 15 TMFDTLLQ-LPLFQGLCHEDFTSILDKVKLHFIKHKAGETIIKSGNPCTQLCFLLKGEIS 73
Query: 321 ITMKRKGKSEVEENGAVEIARCFRGQYFGELALVTNKPRAASAHAIGTVKCLAMDV 376
I K FG N A+S A V + +
Sbjct: 74 IVTNAKENIYTVIEQIEAPYLIEPQSLFG-----MNTNYASSYVAHTEVHTVCISK 124
>2GAU-A nrPDB
Length = 232
Score = 44.8 bits (104), Expect = 7e-05, Method: Composition-based stats.
Identities = 25/150 (16%), Positives = 48/150 (32%), Gaps = 17/150 (11%)
Query: 168 MFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKC-DGVGRCVGNYDNRGSFGELALMY 226
+ K+ V +GD +N + + G I + G FG
Sbjct: 33 IQPFPCKKASTVFSEGDIPNNLFYLYEGKIKILREGVYGRFHISRIVKPGQFFGMRPYFA 92
Query: 227 NTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLKSLEVSERLKV 286
++T A + + ++ N F+++L K L +ER V
Sbjct: 93 EETCSSTAIAVENSKVLAIPVEAIEALLKGNT----SFCRYFLKALA--KELGYAERRTV 146
Query: 287 VDVIGTKVYNDGEQIIAQGDLADSFFIVES 316
+ K +G LA++ I++
Sbjct: 147 T--LTQKHV--------RGRLAETLLILKE 166
Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats.
Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 6/88 (6%)
Query: 296 NDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFRGQYFGELALVT 355
+ ++GD+ ++ F + G++KI + GQ+FG
Sbjct: 39 KKASTVFSEGDIPNNLFYLYEGKIKILREGVYGRFHIS------RIVKPGQFFGMRPYFA 92
Query: 356 NKPRAASAHAIGTVKCLAMDVQAFERLL 383
+ +++A A+ K LA+ V+A E LL
Sbjct: 93 EETCSSTAIAVENSKVLAIPVEAIEALL 120
>2FMY-A nrPDB
Length = 220
Score = 42.9 bits (99), Expect = 2e-04, Method: Composition-based stats.
Identities = 21/118 (17%), Positives = 41/118 (34%), Gaps = 7/118 (5%)
Query: 147 CKDILLFKNLDPEQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGV 206
D L + L+ E+ S VL E+ + + + + +++ G +Y+ +
Sbjct: 6 LTDTNLLEVLNSEEYSGVLKEFREQRYSKKAILYTPNTERNLVFLVKSGRVRVYLAYEDK 65
Query: 207 GRCVGNYDNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKM 264
+ + F T A I A + D F+ I+V+ A M
Sbjct: 66 EFTLAILEAGDIFC-------THTRAFIQAMEDTTILYTDIRNFQNIVVEFPAFSLNM 116
>1O5L-A nrPDB
Length = 213
Score = 41.3 bits (95), Expect = 7e-04, Method: Composition-based stats.
Identities = 17/116 (14%), Positives = 44/116 (37%), Gaps = 6/116 (5%)
Query: 160 QMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGS 218
+ ++L + ++GE V Q D ++ ++ GT +V +G +
Sbjct: 14 DLKKLLPCGKVIVFRKGEIVKHQDDPIEDVLILLEGTLKTEHVSENGKTLEIDEIKPVQI 73
Query: 219 FGELALMYNTPR-AATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
+ + PR + A + + + F +++ K R++ F++ +
Sbjct: 74 IASGFIFSSEPRFPVNVVAGENSKILSIPKEVFLDLLM----KDRELLLFFLKDVS 125
Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats.
Identities = 21/107 (19%), Positives = 41/107 (38%), Gaps = 7/107 (6%)
Query: 285 KVVDVIGTKVYNDGEQIIAQGDLADSFFIVESGEVKITMKRKGKSEVEENGAVEIARCFR 344
K++ V+ GE + Q D + I+ G +K + +E + +
Sbjct: 17 KLLPCGKVIVFRKGEIVKHQDDPIEDVLILLEGTLKTEHVSENGKTLEIDEIKPVQIIAS 76
Query: 345 GQYFGELALVTNKPR-AASAHAIGTVKCLAMDVQAFERLLGPCMEIM 390
G F +++PR + A K L++ + F LL E++
Sbjct: 77 GFIF------SSEPRFPVNVVAGENSKILSIPKEVFLDLLMKDRELL 117
>2ZCW-A nrPDB
Length = 202
Score = 39.0 bits (89), Expect = 0.004, Method: Composition-based stats.
Identities = 18/77 (23%), Positives = 26/77 (33%), Gaps = 4/77 (5%)
Query: 169 FEKLVKEGEHVIDQGDDG--DNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALM 225
K G+ ++ G G D Y + G + V +G + G FGE AL
Sbjct: 6 ETVSFKAGDVILYPGVPGPRDRAYRVLEGLVRLEAVDEEGNALTLRLVRPGGFFGEEALF 65
Query: 226 YNTPRAATITATSPGAL 242
R A + L
Sbjct: 66 -GQERIYFAEAATDVRL 81
>1ATT-A nrPDB
Length = 429
Score = 36.7 bits (83), Expect = 0.019, Method: Composition-based stats.
Identities = 28/159 (17%), Positives = 57/159 (35%), Gaps = 22/159 (13%)
Query: 105 NRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQV 164
RR + + + DD +I PK + ++++ +L + LD + +
Sbjct: 254 KFRYRRVAESTQVLELPFKGDDITMVLILPKLEKTLAKVEQELTPDMLQEWLDELTETLL 313
Query: 165 LDAMFEKLVKEGEHVIDQ-GDDG-DNFY---------VIDRGTFDIYVKCDGVGRCVGNY 213
+ M +++ V +Q D G ++ + ++ G D+YV +
Sbjct: 314 VVHMPRFRIEDSFSVKEQLQDMGLEDLFSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVN 373
Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRR 252
+ E A A+ + G DRVTF+
Sbjct: 374 EEGS---EAA--------ASTVISIAGRSLNSDRVTFKA 401
>4EB1-I nrPDB
Length = 440
Score = 36.3 bits (82), Expect = 0.027, Method: Composition-based stats.
Identities = 32/181 (17%), Positives = 62/181 (34%), Gaps = 31/181 (17%)
Query: 105 NRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDPEQMSQV 164
RR + + + DD +I PK + ++++ +L + LD + +
Sbjct: 265 KFRYRRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEMML 324
Query: 165 LDAMFEKLVKEGEHVIDQ-GDDG--DNFY--------VIDRGTFDIYVKCDGVGRCVGNY 213
+ M +++G + +Q D G D F ++ G D+YV +
Sbjct: 325 VVHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVN 384
Query: 214 DNRGSFGELALMYNTPRAATITATSPGALWGLDRVTFRRIIVKNNAKKRKMYESFIESLP 273
+ E A A+ G +RVTF+ + + FI +P
Sbjct: 385 EEGS---EAA--------ASTAVVIAGRSLNPNRVTFKA---------NRPFLVFIREVP 424
Query: 274 F 274
Sbjct: 425 L 425
>5E44-A nrPDB
Length = 259
Score = 35.9 bits (81), Expect = 0.028, Method: Composition-based stats.
Identities = 13/68 (19%), Positives = 27/68 (39%), Gaps = 2/68 (2%)
Query: 155 NLDPEQMSQVLDAMFEKL-VKEGEHVIDQGDDGDNFYVIDRGTFDIYV-KCDGVGRCVGN 212
L+ ++ Q+ + + K +++G+ + GD+ Y I GT Y G +
Sbjct: 42 TLNDSELDQLDEIIERKKPIQKGQELFKAGDELKCLYAIRSGTIKSYTITEQGDEQITAF 101
Query: 213 YDNRGSFG 220
+ G
Sbjct: 102 HLAGDLVG 109
>3E6B-A nrPDB
Length = 250
Score = 34.4 bits (77), Expect = 0.089, Method: Composition-based stats.
Identities = 16/108 (14%), Positives = 39/108 (36%), Gaps = 6/108 (5%)
Query: 171 KLVKEGEHVIDQGDDGDNFYVIDRGTFDI-YVKCDGVGRCVGNYDNRGSFGELALMYNTP 229
+ +G VI G++ + + G + + DG + + G+L Y T
Sbjct: 35 RDFAKGSAVIMPGEEITSMIFLVEGKIKLDIIFEDGSEKLLYYAGGNSLIGKL---YPTG 91
Query: 230 RAATITATSPG-ALWGLDRVTFRRIIVKNNAKKRKMYESFIESLPFLK 276
TA P W + R + + +++++++ + +
Sbjct: 92 NNIYATAMEPTRTCW-FSEKSLRTVFRTDEDMIFEIFKNYLTKVAYYA 138
>4FHA-A nrPDB
Length = 311
Score = 33.2 bits (74), Expect = 0.21, Method: Composition-based stats.
Identities = 18/112 (16%), Positives = 41/112 (36%), Gaps = 9/112 (8%)
Query: 99 FNAPVINRFTRRASVCAEAYNPDEEEDDAESRIIHPKTDDQRNRLQEACKDILLFKNLDP 158
+N P + A+A + + R++ T + RL + +
Sbjct: 114 YNKPSQEGMYQHFKAIADASDLPIIIYNIPGRVVVELTPETMLRLAD------HPNIIGV 167
Query: 159 EQMSQVLDAMFEKLVKEGEHVIDQGDDGDNFYVID---RGTFDIYVKCDGVG 207
++ + + + + K E +I G+DGD F+ ++ G + +G
Sbjct: 168 KECTSLANMAYLIEHKPEEFLIYTGEDGDAFHAMNLGADGVISVASHTNGDE 219
>1Z5V-A nrPDB
Length = 474
Score = 32.1 bits (71), Expect = 0.50, Method: Composition-based stats.
Identities = 24/152 (15%), Positives = 51/152 (33%), Gaps = 19/152 (12%)
Query: 276 KSLEVSERLKVVDVIGTKVYNDGEQIIAQGDLADS--FFI----VESGEVKITMKRKGKS 329
+S+ + V+DV+ ++ +++ G + +I + GEV T K
Sbjct: 280 QSVASVRKTTVLDVMR-RLLQPKNVMVSTGRDRQTNHCYIAILNIIQGEVDPTQVHKSLQ 338
Query: 330 EVEENGAVEIARCFRGQYFGELALVTNKP------RAASAHAIGTVKCLAMDVQAFERLL 383
+ E ++AL P R + ++ FER
Sbjct: 339 RIRERKLANFIPWGPASI--QVALSRKSPYLPSAHRVSGLMMANHTSISSL----FERTC 392
Query: 384 GPCMEIMKRNIATYEEQLVALFGTNMDIVEPT 415
++ KR + + +F N D ++ +
Sbjct: 393 RQYDKLRKREAFLEQFRKEDMFKDNFDEMDTS 424
>1XKW-A nrPDB
Length = 665
Score = 32.1 bits (71), Expect = 0.52, Method: Composition-based stats.
Identities = 13/89 (14%), Positives = 28/89 (31%), Gaps = 3/89 (3%)
Query: 33 LQHFTRLQQENERKGAARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEE 92
+ + Q + +R+ G + +N + R D EN +E+
Sbjct: 440 VSYAEVYQPQADRQTWNSEPLSPVEGKTYETGIKGELADGRLNLSLAAFRIDLENNPQED 499
Query: 93 AAEAGAFNAPVINRFTRRASVCAEAYNPD 121
G N P + V ++ + +
Sbjct: 500 PDHPGPPNNPF---YISGGKVRSQGFELE 525
>6CXO-A nrPDB
Length = 529
Score = 29.4 bits (64), Expect = 3.0, Method: Composition-based stats.
Identities = 21/121 (17%), Positives = 42/121 (34%), Gaps = 4/121 (3%)
Query: 201 VKCDGVGRCVGNYDNRGSFGELALMYNTPRAATITATSPGAL-WGLDRVTFRRIIVKNNA 259
D V +Y+ FG L Y T + + + + + LD+ + + V N
Sbjct: 297 TFLDDVKALPTSYEKGEYFGFLE-TYGTHYSTSGSLGGQYEIVYVLDKASMKEKGVDLND 355
Query: 260 KKRKMYESFIESLPFLKSLEVSERLKVVDVIGTKVYNDGEQ--IIAQGDLADSFFIVESG 317
K + + +P L+ + V+ G ++G+ I + D + G
Sbjct: 356 VKHCLGFNMDLRIPLQDDLKDASVTASVNADGCIKTDNGKTVDITRDNIIDDVISFIRGG 415
Query: 318 E 318
Sbjct: 416 T 416
>5MMI-U nrPDB
Length = 198
Score = 29.0 bits (63), Expect = 4.4, Method: Composition-based stats.
Identities = 22/181 (12%), Positives = 52/181 (28%), Gaps = 9/181 (4%)
Query: 48 AARFGHEGRTWGDAGAAAGGGIPSKGVNFAEEPMRSDSENGEEEEAAEAGAFNAPVINRF 107
++ F + + + IP+K + + N P
Sbjct: 12 SSSFAFSNPSSNVSATSFTFQIPNKKAQISCISSKKLHTQKSFNFHDAVTPMNKPSF-GR 70
Query: 108 TRRASVCAEAYNPDEEEDDAESRIIHPKT-----DDQRNRLQEACKDILLFKNLDPEQMS 162
+ EA P EE K + + + + + + ++
Sbjct: 71 DLMVAQATEAVAPTTEEAATSQPKTSKKAKKLKYPRRILDVYQILQS-PIITEAAIKNIA 129
Query: 163 QVLDAMFEKLVKEGEHVIDQGDDGDNFYVIDRGTFDIYVKCDGVGRCVGNYDNRGSFGEL 222
+F V+ + +I + NF+ + + ++ DG + + + EL
Sbjct: 130 DENSLLFTVDVRADKKMIR--EAISNFFGVKVRKVNTLIRPDGTKKAYIMLNKEYNASEL 187
Query: 223 A 223
A
Sbjct: 188 A 188
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.304 0.122 0.293
Lambda K H
0.267 0.0376 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,393,741
Number of Sequences: 36641
Number of extensions: 491681
Number of successful extensions: 1838
Number of sequences better than 10.0: 70
Number of HSP's better than 10.0 without gapping: 97
Number of HSP's successfully gapped in prelim test: 25
Number of HSP's that attempted gapping in prelim test: 1416
Number of HSP's gapped (non-prelim): 210
length of query: 416
length of database: 10,336,785
effective HSP length: 100
effective length of query: 316
effective length of database: 6,672,685
effective search space: 2108568460
effective search space used: 2108568460
T: 11
A: 40
X1: 16 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.0 bits)
S2: 60 (27.8 bits)