BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P31142 (281 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1URH-A nrPDB 566 e-162 4JGT-A nrPDB 204 4e-53 5WQK-A nrPDB 202 9e-53 1BOH-A nrPDB 175 2e-44 3UTN-X nrPDB 135 3e-32 1UAR-A nrPDB 132 2e-31 3AAX-A nrPDB 112 2e-25 1H4M-X nrPDB 96 1e-20 3P3A-A nrPDB 94 8e-20 3HZU-A nrPDB 86 2e-17 1OKG-A nrPDB 76 2e-14 2WLX-A nrPDB 64 9e-11 1TQ1-A nrPDB 41 5e-04 2EG4-A nrPDB 40 0.001 1YT8-A nrPDB 39 0.004 6BEV-A nrPDB 32 0.23 1X87-A nrPDB 31 0.71 3D1P-A nrPDB 30 0.84 5ZL6-A nrPDB 29 2.1 3LQ1-A nrPDB 28 4.1 4M4D-A nrPDB 28 4.3 5HTO-A nrPDB 27 6.8 5HX0-A nrPDB 27 7.1 6EFR-A nrPDB 27 7.5 4KHO-A nrPDB 27 8.0 4KHA-A nrPDB 27 9.3 >1URH-A nrPDB Length = 280 Score = 566 bits (1459), Expect = e-162, Method: Compositional matrix adjust. Identities = 280/280 (100%), Positives = 280/280 (100%) Query: 2 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH Sbjct: 1 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 60 Query: 62 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGG 121 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGG Sbjct: 61 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGG 120 Query: 122 GLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFN 181 GLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFN Sbjct: 121 GLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFN 180 Query: 182 AEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSG 241 AEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSG Sbjct: 181 AEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSG 240 Query: 242 VTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPVK 281 VTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPVK Sbjct: 241 VTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPVK 280 >4JGT-A nrPDB Length = 299 Score = 204 bits (518), Expect = 4e-53, Method: Compositional matrix adjust. Identities = 111/274 (40%), Positives = 152/274 (55%), Gaps = 8/274 (2%) Query: 7 VGADWLAEHIDDPE----IQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHT 62 V A W+AE + P +Q++DA P + R+ +E+ HIPGA FFDI+ SD T Sbjct: 21 VSAQWVAEALRAPRAGQPLQLLDASWYLP-KLGRDARREFEERHIPGAAFFDIDQCSDRT 79 Query: 63 SPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGN--LFSAPRAWWMLRTFGVEKVSILG 120 SP HMLP E FA LGV H+++YD + L+SAPR WWM R FG VS+L Sbjct: 80 SPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLD 139 Query: 121 GGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARF 180 GGL W R +L L G + EF A +P + D+ Q++D+R RF Sbjct: 140 GGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRF 199 Query: 181 NAEVDEPRPGLRRGHIPGALNVPWTE-LVREGELKTTDELDAIFFGRGVSYDKPIIVSCG 239 EPR G+ GHIPG +N+P+T+ L +EG K+ +E+ +F + V KP++ +CG Sbjct: 200 RGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCG 259 Query: 240 SGVTAAVVLLALATLDVPNVKLYDGAWSEWGARA 273 SGVTA V L P+V +YDG+W EW RA Sbjct: 260 SGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRA 293 >5WQK-A nrPDB Length = 293 Score = 202 bits (515), Expect = 9e-53, Method: Compositional matrix adjust. Identities = 110/275 (40%), Positives = 154/275 (56%), Gaps = 8/275 (2%) Query: 6 FVGADWLAEHIDDPE----IQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 V A W+AE + P ++++DA P + R+ +E+ HIPGA FFDI+ SDH Sbjct: 6 LVSAQWVAEALKAPRSSQPLKLLDASWYLP-KLGRDARREFEERHIPGAAFFDIDRSSDH 64 Query: 62 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYD--EGNLFSAPRAWWMLRTFGVEKVSIL 119 TSP HMLP FA LGV+ H+++YD + L+SAPR WWM R FG VS+L Sbjct: 65 TSPYDHMLPNATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHSVSLL 124 Query: 120 GGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAAR 179 GG W +L + G EF+A +P + D+L Q++DAR A R Sbjct: 125 DGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGR 184 Query: 180 FNAEVDEPRPGLRRGHIPGALNVPWTE-LVREGELKTTDELDAIFFGRGVSYDKPIIVSC 238 F EPR G+ GHIPG++N+P+TE L EG K+ +E+ +F + V KP++ +C Sbjct: 185 FQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPLVATC 244 Query: 239 GSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARA 273 GSGVTA+ V+L +V +YDG+W EW RA Sbjct: 245 GSGVTASHVVLGAFLSGKSDVPVYDGSWVEWYMRA 279 >1BOH-A nrPDB Length = 296 Score = 175 bits (443), Expect = 2e-44, Method: Compositional matrix adjust. Identities = 103/276 (37%), Positives = 140/276 (50%), Gaps = 10/276 (3%) Query: 6 FVGADWLAEHID----DPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 V WLAE + P ++++DA SPG R +EYL H+PGA FFDIE D Sbjct: 9 LVSTKWLAESVRAGKVGPGLRVLDASWYSPGT--REARKEYLERHVPGASFFDIEECRDK 66 Query: 62 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNL--FSAPRAWWMLRTFGVEKVSIL 119 SP MLP FA + LG++ D H++VYD +L F APR WWM R FG VS+L Sbjct: 67 ASPYEVMLPSEAGFADYVGSLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVL 126 Query: 120 GGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAAR 179 GG W ++ + F A N + VL Q++D+R R Sbjct: 127 NGGFRNWLKEGHPVTSEPSRPEPAIFKATLNRSLLKTYEQVLENLESKRFQLVDSRAQGR 186 Query: 180 FNAEVDEPRP-GLRRGHIPGALNVPWTELVRE-GELKTTDELDAIFFGRGVSYDKPIIVS 237 + EP GL GHI G++N+P+ + E G K+ +EL A+F + V KP+I + Sbjct: 187 YLGTQPEPDAVGLDSGHIRGSVNMPFMNFLTEDGFEKSPEELRAMFEAKKVDLTKPLIAT 246 Query: 238 CGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARA 273 C GVTA + LA P+V +YDG+W EW RA Sbjct: 247 CRKGVTACHIALAAYLCGKPDVAIYDGSWFEWFHRA 282 >3UTN-X nrPDB Length = 327 Score = 135 bits (339), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 93/274 (33%), Positives = 127/274 (46%), Gaps = 38/274 (13%) Query: 24 IDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELG 83 +DA P + N IP ++FFDI+A+SD SP PHM P + F AM LG Sbjct: 50 VDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAMSNLG 109 Query: 84 VNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEG 143 V +D L+VYD FS+PR W L G KV +L ++ L+ V Sbjct: 110 VQKDDILVVYDRVGNFSSPRCAWTLGVMGHPKVYLL-NNFNQYREFKYPLDSSKV----- 163 Query: 144 EFNAAFNP------EAVVKVTDVLLASHENTAQII------------DARPAARFNAEVD 185 AAF+P E+ D + +E Q++ DAR RF Sbjct: 164 ---AAFSPYPKSHYESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEP 220 Query: 186 EPRPGLRRGHIPGALNVPWTELVREGELKTTDEL-DAIF---------FGRGVSYDKPII 235 EPR + GHIPG +P+ L+ + E KT E +AI F + KP I Sbjct: 221 EPRSDIPSGHIPGTQPLPYGSLL-DPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTI 279 Query: 236 VSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW 269 SCG+GV+ ++ AL VPNV+LYDG+W+EW Sbjct: 280 CSCGTGVSGVIIKTALELAGVPNVRLYDGSWTEW 313 >1UAR-A nrPDB Length = 285 Score = 132 bits (331), Expect = 2e-31, Method: Compositional matrix adjust. Identities = 84/283 (29%), Positives = 137/283 (48%), Gaps = 22/283 (7%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V DW+ EH++DP++++++ D ++ Y GHIPGA D + D P+ Sbjct: 9 LVSTDWVQEHLEDPKVRVLEV--------DEDILL-YDTGHIPGAQKIDWQ--RDFWDPV 57 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 E FA M LG++ D +++Y + N + A A+W + G + V ++ GG Sbjct: 58 VRDFISEEEFAKLMERLGISNDTTVVLYGDKNNWWAAYAFWFFKYNGHKDVRLMNGGRQK 117 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLAS----HENTAQIIDARPAARFN 181 W + L P G + + E++ D +L E ++D R + Sbjct: 118 WVEEGRPLTTEVPSYPPGRYEVPYRDESIRAYRDDVLEHIIKVKEGKGALVDVRSPQEYR 177 Query: 182 AEV----DEPRPG-LRRGHIPGALNVPWTELVR-EGELKTTDELDAIFFGRGVSYDKPII 235 E+ D P+ G LR GHIPGA N+PW + V +G K+ +EL A++ G++ DK I+ Sbjct: 178 GELTHMPDYPQEGALRAGHIPGAKNIPWAKAVNPDGTFKSAEELRALYEPLGITKDKDIV 237 Query: 236 VSCGSGVTAAVVLLALAT-LDVPNVKLYDGAWSEWGARADLPV 277 V C ++ L L P+VK YDG+W+EWG +P+ Sbjct: 238 VYCRIAERSSHSWFVLKYLLGYPHVKNYDGSWTEWGNLVGVPI 280 >3AAX-A nrPDB Length = 277 Score = 112 bits (280), Expect = 2e-25, Method: Compositional matrix adjust. Identities = 80/280 (28%), Positives = 126/280 (45%), Gaps = 19/280 (6%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V ADW ++ P++ ++ ED + Y HI GA+ D +D P+ Sbjct: 7 LVSADWAESNLHAPKVVFVEV------DEDTSA---YDRDHIAGAIKLDWR--TDLQDPV 55 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 + F+ + E G+ + +I+Y N + A A+W + +G EKV +L GG Sbjct: 56 KRDFVDAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKK 115 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVD 185 W+ D L V P + A+ + D +LA+ N +ID R F+ ++ Sbjct: 116 WELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAI-NVKNLIDVRSPDEFSGKIL 174 Query: 186 EP-----RPGLRRGHIPGALNVPWTELVRE-GELKTTDELDAIFFGRGVSYDKPIIVSCG 239 P R GHIPGA+NVPW+ E G K+ +EL ++ G+ K I C Sbjct: 175 APAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCR 234 Query: 240 SGVTAAVVLLALAT-LDVPNVKLYDGAWSEWGARADLPVE 278 G ++ L L NVK YDG+W+E+G+ P+E Sbjct: 235 IGERSSHTWFVLRELLGHQNVKNYDGSWTEYGSLVGAPIE 274 >1H4M-X nrPDB Length = 271 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 78/261 (29%), Positives = 107/261 (40%), Gaps = 12/261 (4%) Query: 24 IDARMASPGQ--EDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRE 81 + AR+++P D A Y GHIPGA F D + P P + P E E Sbjct: 16 LQARLSAPELILVDLTSAARYAEGHIPGARFVDPKRTQLGQPPAPGLQPPREQLESLFGE 75 Query: 82 LGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELP 141 LG + +VYD+ A R W+L G ++ L GGL W +D L ELP Sbjct: 76 LGHRPEAVYVVYDDEGGGWAGRFIWLLDVIGQQRYHYLNGGLTAWLAEDRPLSR---ELP 132 Query: 142 E---GEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPG 198 G + + E +L I DAR + E G GHIPG Sbjct: 133 APAGGPVALSLHDEPTASRDYLLGRLGAADLAIWDARSPQEYRGEKVLAAKG---GHIPG 189 Query: 199 ALNVPWTELVREGE-LKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVP 257 A+N WT + L+ ++ G++ DK I+ C + + + L L P Sbjct: 190 AVNFEWTAAMDPSRALRIRTDIAGRLEELGITPDKEIVTHCQTHHRSGLTYLIAKALGYP 249 Query: 258 NVKLYDGAWSEWGARADLPVE 278 VK Y G+W EWG D PVE Sbjct: 250 RVKGYAGSWGEWGNHPDTPVE 270 >3P3A-A nrPDB Length = 320 Score = 93.6 bits (231), Expect = 8e-20, Method: Compositional matrix adjust. Identities = 86/286 (30%), Positives = 130/286 (45%), Gaps = 34/286 (11%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V ADWLA ++ P + I+++ D +V Y GHIPGAV D +D P Sbjct: 42 LVTADWLASNLGRPGLVIVES--------DEDVLL-YDTGHIPGAVKIDWH--TDLNDPA 90 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 E FA M GV +D +++Y + + + A A W+ FG V +L GG Sbjct: 91 VRDYINGEQFAALMDRKGVTRDDTVVIYGDKSNWWAAYAMWVFHLFGHPDVRLLDGGRDL 150 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHEN-------TAQIIDARPAA 178 W + +E+P + + VV+ D + + ++ +ID R Sbjct: 151 WVSTG---RDTTLEVPTRQTSGY----PVVERNDAPIRAFKDDVLRVLGKEPLIDVRSPQ 203 Query: 179 RFNAEV----DEPRPG-LRRGHIPGALNVPWTELVR-EGELKTTDELDAIFFGRGVSYDK 232 + E D P G LR GHIP A++VPW++ +G + EL+ I +G DK Sbjct: 204 EYTGERTHMPDYPEEGALRGGHIPTAVSVPWSKAAYDDGRFRARAELEEI-YGFVKPDDK 262 Query: 233 PIIVSCGSGVTAAVVLLALAT-LDVPNVKLYDGAWSEWGARADLPV 277 P IV C G ++ L L PNV+ YDG+W+EWG +P+ Sbjct: 263 P-IVYCRIGERSSHTWFVLTYLLGHPNVRNYDGSWTEWGNAVRVPI 307 >3HZU-A nrPDB Length = 318 Score = 85.9 bits (211), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 80/286 (27%), Positives = 126/286 (44%), Gaps = 34/286 (11%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V ADWL+ H+ P + I+++ D +V Y GHIPGAV D +D P Sbjct: 41 LVTADWLSAHMGAPGLAIVES--------DEDVLL-YDVGHIPGAVKIDWH--TDLNDPR 89 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 E FA M G+ +D +++Y + + + A A W+ FG V +L GG Sbjct: 90 VRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGG--- 146 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHEN-------TAQIIDARPAA 178 RD L E L P VV+ D + + + +ID R Sbjct: 147 --RDLWLAERRETTLDVPTKTCTGYP--VVQRNDAPIRAFRDDVLAILGAQPLIDVRSPE 202 Query: 179 RFNAEV----DEPRPG-LRRGHIPGALNVPWTELVRE-GELKTTDELDAIFFGRGVSYDK 232 + + D P G LR GHIP A+++PW + E G ++ +EL+ ++ ++ D Sbjct: 203 EYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLY--DFINPDD 260 Query: 233 PIIVSCGSGVTAAVVLLALA-TLDVPNVKLYDGAWSEWGARADLPV 277 +V C G ++ L L +V+ YDG+W+EWG +P+ Sbjct: 261 QTVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPI 306 >1OKG-A nrPDB Length = 373 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 80/282 (28%), Positives = 125/282 (44%), Gaps = 30/282 (10%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEA-LSD--HT 62 F+ +A+H+ E +I+D R + ++ ++ +Y H+ A+ D++ LS T Sbjct: 15 FLDPSEVADHL--AEYRIVDCRYSLKIKDHGSI--QYAKEHVKSAIRADVDTNLSKLVPT 70 Query: 63 SPLPHMLPRPETFAVAMRELGVNQDKHLIVYD-EGNLFSAPRAWWMLRTFGVEKVSILGG 121 S H LP F G+ + ++ YD E R WWML + G + ++ G Sbjct: 71 STARHPLPPCAEFIDWCMANGMAGELPVLCYDDECGAMGGCRLWWMLNSLGADAY-VING 129 Query: 122 GLAGWQRDDLLLEEG-AVELPEGE----FNAAFNPEAVVKVTDVLLASHENTAQIIDARP 176 G + L +E G LP F AF +V A I DAR Sbjct: 130 GFQACKAAGLEMESGEPSSLPRPATHWPFKTAFQHHYLVDEI-------PPQAIITDARS 182 Query: 177 AARFNAEVDEPRPGLRRGHIPGALNVPWT-ELVREGE---LKTTDELD----AIFFGRGV 228 A RF + V GHI GA N+P+T LV G+ L++ +E+ + G G Sbjct: 183 ADRFASTVRPYAADKMPGHIEGARNLPYTSHLVTRGDGKVLRSEEEIRHNIMTVVQGAGD 242 Query: 229 SYD-KPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW 269 + D + SCGSGVTA + + + L + + LY G+WSE+ Sbjct: 243 AADLSSFVFSCGSGVTACINIALVHHLGLGHPYLYCGSWSEY 284 >2WLX-A nrPDB Length = 423 Score = 63.5 bits (153), Expect = 9e-11, Method: Compositional matrix adjust. Identities = 56/249 (22%), Positives = 105/249 (42%), Gaps = 18/249 (7%) Query: 42 YLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSA 101 YL HIPGA + D + + PL + + E + + G+ D +I+Y ++++A Sbjct: 161 YLISHIPGADYIDTNEV--ESEPLWNKV-SDEQLKAMLAKHGIRHDTTVILYGR-DVYAA 216 Query: 102 PRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGA----VELPEGEFNAAFNPEAVVKV 157 R ++ GV+ V +L GG W L +E G P+ P+ ++ + Sbjct: 217 ARVAQIMLYAGVKDVRLLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDM 276 Query: 158 TDVLLASHENTAQIIDARPAARFNAEVD-----EPR---PGLRRGHIPGALNVPWTELVR 209 H A ++ R F +P+ G R GH G+ + + Sbjct: 277 EQARGLLHRQDASLVSIRSWPEFIGTTSGYSYIKPKGEIAGARWGHA-GSDSTHMEDFHN 335 Query: 210 -EGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSE 268 +G +++ D++ A++ + ++ + CG+G A+ + + NV +YDG W E Sbjct: 336 PDGTMRSADDITAMWKAWNIKPEQQVSFYCGTGWRASETFMYARAMGWKNVSVYDGGWYE 395 Query: 269 WGARADLPV 277 W + PV Sbjct: 396 WSSDPKNPV 404 >1TQ1-A nrPDB Length = 129 Score = 41.2 bits (95), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 38/128 (29%), Positives = 53/128 (41%), Gaps = 22/128 (17%) Query: 153 AVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGE 212 +V D+LLA H + +D R F+ +GH GA+NVP+ G Sbjct: 21 SVTVAHDLLLAGH----RYLDVRTPEEFS-----------QGHACGAINVPYMNRGASGM 65 Query: 213 LKTTDELDAI--FFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWG 270 K TD L+ + FG+ IIV C SG + L VK G +S W Sbjct: 66 SKNTDFLEQVSSHFGQ----SDNIIVGCQSGGRSIKATTDLLHAGFTGVKDIVGGYSAW- 120 Query: 271 ARADLPVE 278 A+ LP + Sbjct: 121 AKNGLPTK 128 >2EG4-A nrPDB Length = 230 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 68/249 (27%), Positives = 97/249 (38%), Gaps = 47/249 (18%) Query: 42 YLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAM--------RELGVNQDKHLIVY 93 Y GH+PGA D+ A P + R E A+ + LG+ +++Y Sbjct: 18 YEAGHLPGARHLDLSA--------PKLRLREEAELKALEGGLTELFQTLGLRSP--VVLY 67 Query: 94 DEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEA 153 DEG R + L G+E V + GW+ EE E E Sbjct: 68 DEGLTSRLCRTAFFLGLGGLE-VQLW---TEGWEPYATEKEEPKPE----------RTEV 113 Query: 154 VVKV-TDVLLASHENTAQ--IIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVRE 210 V K+ D LL + E ++D R F +V P R G IPG+ N P Sbjct: 114 VAKLRRDWLLTADEAARHPLLLDVRSPEEFQGKVHPP-CCPRGGRIPGSKNAPL------ 166 Query: 211 GELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWG 270 EL + E + G+ + + V C SG +AV L +L V + Y G+ EW Sbjct: 167 -ELFLSPE--GLLERLGLQPGQEVGVYCHSGARSAVAFFVLRSLGV-RARNYLGSMHEW- 221 Query: 271 ARADLPVEP 279 + LP EP Sbjct: 222 LQEGLPTEP 230 Score = 28.9 bits (63), Expect = 2.6, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 13/98 (13%) Query: 187 PRPGLRRGHIPGA----LNVPWTELVREGELKTTD-ELDAIFFGRGVSYDKPIIV---SC 238 PRP GH+PGA L+ P L E ELK + L +F G+ P+++ Sbjct: 14 PRPAYEAGHLPGARHLDLSAPKLRLREEAELKALEGGLTELFQTLGLR--SPVVLYDEGL 71 Query: 239 GSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLP 276 S + L L L+ V+L+ W + + P Sbjct: 72 TSRLCRTAFFLGLGGLE---VQLWTEGWEPYATEKEEP 106 >1YT8-A nrPDB Length = 539 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 50/182 (27%), Positives = 73/182 (40%), Gaps = 37/182 (20%) Query: 85 NQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQ-------RDDLLLEEGA 137 +D + VYD+G AP A L G V++L GGL+GW+ RD + + Sbjct: 61 RRDTPITVYDDGEGL-APVAAQRLHDLGYSDVALLDGGLSGWRNAGGELFRDVNVPSKAF 119 Query: 138 VELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIP 197 EL E E + P + LL + A I+DAR RF+ + IP Sbjct: 120 GELVEAERH---TPSLAAEEVQALLDARAE-AVILDAR---RFDE--------YQTMSIP 164 Query: 198 GALNVPWTELV-REGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDV 256 G ++VP ELV R EL +IV+C + + +L + Sbjct: 165 GGISVPGAELVLRVAELAPDPR-------------TRVIVNCAGRTRSIIGTQSLLNAGI 211 Query: 257 PN 258 PN Sbjct: 212 PN 213 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 32/116 (27%), Positives = 51/116 (43%), Gaps = 21/116 (18%) Query: 165 HENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFF 224 H+ T ++D R + A GH+PG+ + P +LV+E TD + ++ Sbjct: 279 HDRTTYLLDVRTPEEYEA-----------GHLPGSRSTPGGQLVQE-----TDHVASVRG 322 Query: 225 GRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGA-RADLPVEP 279 R V D + + S A + +A LD L + +SE GA A LP +P Sbjct: 323 ARLVLVDDDGVRANMSASWLAQMGWQVAVLD----GLSEADFSERGAWSAPLPRQP 374 Score = 27.3 bits (59), Expect = 8.5, Method: Compositional matrix adjust. Identities = 26/84 (30%), Positives = 35/84 (41%), Gaps = 15/84 (17%) Query: 195 HIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATL 254 HIPGA V ++L + E T E +++CGS + A + + L Sbjct: 408 HIPGAAWVLRSQLKQALERLGTAER--------------YVLTCGSSLLARFAVAEVQAL 453 Query: 255 DVPNVKLYDGAWSEWGARADLPVE 278 V L DG S W A A LP E Sbjct: 454 SGKPVFLLDGGTSAWVA-AGLPTE 476 >6BEV-A nrPDB Length = 135 Score = 32.3 bits (72), Expect = 0.23, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 35/82 (42%), Gaps = 12/82 (14%) Query: 194 GHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKP------IIVSCGSGVTAAVV 247 G IPGALN+P + EL++ +++ F S +KP ++ C G Sbjct: 55 GTIPGALNIPVS------ELESALQMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQA 108 Query: 248 LLALATLDVPNVKLYDGAWSEW 269 +L + Y GA+ EW Sbjct: 109 TQLARSLGYTGARNYAGAYREW 130 >1X87-A nrPDB Length = 551 Score = 30.8 bits (68), Expect = 0.71, Method: Compositional matrix adjust. Identities = 16/63 (25%), Positives = 29/63 (46%) Query: 35 DRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYD 94 D+ A + LNG+IP + D A P ++ ++ A +R + Q + + +D Sbjct: 258 DQTSAHDPLNGYIPAGLTLDEAAELRARDPKQYIARAKQSIAAHVRAMLAMQKQGAVTFD 317 Query: 95 EGN 97 GN Sbjct: 318 YGN 320 >3D1P-A nrPDB Length = 139 Score = 30.4 bits (67), Expect = 0.84, Method: Compositional matrix adjust. Identities = 30/128 (23%), Positives = 50/128 (39%), Gaps = 16/128 (12%) Query: 157 VTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTT 216 V+++ S E+ +I+ +V EP HIP ++NVP+ Sbjct: 19 VSNIQSYSFEDMKRIVGKHDPNVVLVDVREPSE-YSIVHIPASINVPYRSH------PDA 71 Query: 217 DELDAIFFGRGVSYDKP-----IIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW-- 269 LD + F + + KP +I C SG ++ N LY G+ ++W Sbjct: 72 FALDPLEFEKQIGIPKPDSAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVS 131 Query: 270 --GARADL 275 G + DL Sbjct: 132 HGGDKLDL 139 >5ZL6-A nrPDB Length = 381 Score = 29.3 bits (64), Expect = 2.1, Method: Compositional matrix adjust. Identities = 16/30 (53%), Positives = 16/30 (53%), Gaps = 1/30 (3%) Query: 251 LATLDVPNVKLYDGAWSEWGARA-DLPVEP 279 AT D PNV D SEW DLPVEP Sbjct: 169 FATADTPNVDYVDFQISEWQRLTHDLPVEP 198 >3LQ1-A nrPDB Length = 578 Score = 28.1 bits (61), Expect = 4.1, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 34/71 (47%), Gaps = 6/71 (8%) Query: 197 PGALNVPWTELVREGELKT----TDELDAIFFGRGVSY--DKPIIVSCGSGVTAAVVLLA 250 PG+ + P ++ E + DE A FF G++ +P+++ C SG AA A Sbjct: 33 PGSRSTPLALMMAEHPILKIYVDVDERSAGFFALGLAKASKRPVVLLCTSGTAAANYFPA 92 Query: 251 LATLDVPNVKL 261 +A ++ + L Sbjct: 93 VAEANLSQIPL 103 >4M4D-A nrPDB Length = 467 Score = 28.1 bits (61), Expect = 4.3, Method: Compositional matrix adjust. Identities = 16/57 (28%), Positives = 33/57 (57%), Gaps = 5/57 (8%) Query: 15 HIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPR 71 H D ++++I++++ G + N+ Q +LN ++ +++ D+ A PLP LPR Sbjct: 382 HPDKAQVRLIESKV---GMFNVNLFQAFLNYYLLNSLYPDVNAELAQGFPLP--LPR 433 >5HTO-A nrPDB Length = 346 Score = 27.3 bits (59), Expect = 6.8, Method: Compositional matrix adjust. Identities = 13/45 (28%), Positives = 25/45 (55%) Query: 219 LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYD 263 ++ ++F RG KP IV GSG+ V+ + ++ +V ++D Sbjct: 21 MENLYFQRGSMTPKPKIVLVGSGMIGGVMATLIVQKNLGDVVMFD 65 >5HX0-A nrPDB Length = 402 Score = 27.3 bits (59), Expect = 7.1, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 36/92 (39%), Gaps = 11/92 (11%) Query: 35 DRNVAQEYLNGHI-PGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVY 93 DR V E H+ P + +++ T P PE + G +QD L+ Sbjct: 80 DRKVFGEKGTNHVDPNSYLVSVKSKDGKT-----WTPEPEL--IYSHPFGGSQDPCLLQL 132 Query: 94 DEGNLFSAPRAWWMLRTFGVEKVS---ILGGG 122 +G + A W LR G+E + L GG Sbjct: 133 KDGTILCASYGWAFLRPDGMENLKKPYFLAGG 164 >6EFR-A nrPDB Length = 522 Score = 27.3 bits (59), Expect = 7.5, Method: Compositional matrix adjust. Identities = 12/32 (37%), Positives = 20/32 (62%) Query: 12 LAEHIDDPEIQIIDARMASPGQEDRNVAQEYL 43 LA I D E+Q ++ ++ GQ+ VA+E+L Sbjct: 484 LANQISDEEMQKLNYKVDGEGQDPAKVAKEFL 515 >4KHO-A nrPDB Length = 299 Score = 27.3 bits (59), Expect = 8.0, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 162 LASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDA 221 + + +I + RPA N + RP L +PG + + + + L TT +D Sbjct: 7 VVEQDKLIEIRNRRPAVLDNVYI---RPALEGKRVPGKVEIHQNGIRYQSPLSTTQRVDV 63 Query: 222 IF 223 +F Sbjct: 64 LF 65 >4KHA-A nrPDB Length = 410 Score = 26.9 bits (58), Expect = 9.3, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 27/62 (43%), Gaps = 3/62 (4%) Query: 162 LASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDA 221 + + +I + RPA N + RP L +PG + + + + L TT +D Sbjct: 5 VVEQDKLIEIRNRRPAVLDNVYI---RPALEGKRVPGKVEIHQNGIRYQSPLSTTQRVDV 61 Query: 222 IF 223 +F Sbjct: 62 LF 63 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1URH-A nrPDB 374 e-104 5WQK-A nrPDB 336 7e-93 4JGT-A nrPDB 335 1e-92 1BOH-A nrPDB 319 1e-87 1UAR-A nrPDB 312 1e-85 3AAX-A nrPDB 297 4e-81 3HZU-A nrPDB 275 2e-74 3P3A-A nrPDB 270 5e-73 1H4M-X nrPDB 262 1e-70 3UTN-X nrPDB 254 3e-68 2WLX-A nrPDB 238 3e-63 1OKG-A nrPDB 237 6e-63 2EG4-A nrPDB 169 1e-42 1TQ1-A nrPDB 106 9e-24 Sequences not found previously or not previously below threshold: 1YT8-A nrPDB 65 4e-11 6BEV-A nrPDB 64 9e-11 3D1P-A nrPDB 63 2e-10 3ICS-A nrPDB 47 8e-06 2JTQ-A nrPDB 44 8e-05 3NTA-A nrPDB 42 2e-04 1QB0-A nrPDB 41 9e-04 1C25-A nrPDB 39 0.002 4WH9-A nrPDB 37 0.007 1GN0-A nrPDB 36 0.018 1T3K-A nrPDB 33 0.16 3OP3-A nrPDB 31 0.46 2J13-A nrPDB 31 0.50 2VSW-A nrPDB 31 0.74 4CMR-A nrPDB 31 0.83 5ND4-A nrPDB 30 1.0 2Q9V-A nrPDB 30 1.5 5ZYS-A nrPDB 29 2.9 >1URH-A nrPDB Length = 280 Score = 374 bits (961), Expect = e-104, Method: Composition-based stats. Identities = 280/280 (100%), Positives = 280/280 (100%) Query: 2 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH Sbjct: 1 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 60 Query: 62 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGG 121 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGG Sbjct: 61 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGG 120 Query: 122 GLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFN 181 GLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFN Sbjct: 121 GLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFN 180 Query: 182 AEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSG 241 AEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSG Sbjct: 181 AEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSG 240 Query: 242 VTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPVK 281 VTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPVK Sbjct: 241 VTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVEPVK 280 >5WQK-A nrPDB Length = 293 Score = 336 bits (861), Expect = 7e-93, Method: Composition-based stats. Identities = 109/275 (39%), Positives = 154/275 (56%), Gaps = 8/275 (2%) Query: 6 FVGADWLAEHIDDPE----IQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 V A W+AE + P ++++DA P + R+ +E+ HIPGA FFDI+ SDH Sbjct: 6 LVSAQWVAEALKAPRSSQPLKLLDASWYLP-KLGRDARREFEERHIPGAAFFDIDRSSDH 64 Query: 62 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYD--EGNLFSAPRAWWMLRTFGVEKVSIL 119 TSP HMLP FA LGV+ H+++YD + L+SAPR WWM R FG VS+L Sbjct: 65 TSPYDHMLPNATHFADYAGSLGVSAATHVVIYDGSDQGLYSAPRVWWMFRAFGHHSVSLL 124 Query: 120 GGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAAR 179 GG W +L + G EF+A +P + D+L Q++DAR A R Sbjct: 125 DGGFRHWLNQNLPISSGKSHSEPAEFSAQLDPSFIKTHEDILENLDARRFQVVDARAAGR 184 Query: 180 FNAEVDEPRPGLRRGHIPGALNVPWTELV-REGELKTTDELDAIFFGRGVSYDKPIIVSC 238 F EPR G+ GHIPG++N+P+TE + EG K+ +E+ +F + V KP++ +C Sbjct: 185 FQGTQPEPRDGIEPGHIPGSVNIPFTEFLTNEGLEKSPEEIKRLFKEKKVDLSKPLVATC 244 Query: 239 GSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARA 273 GSGVTA+ V+L +V +YDG+W EW RA Sbjct: 245 GSGVTASHVVLGAFLSGKSDVPVYDGSWVEWYMRA 279 >4JGT-A nrPDB Length = 299 Score = 335 bits (859), Expect = 1e-92, Method: Composition-based stats. Identities = 110/275 (40%), Positives = 152/275 (55%), Gaps = 8/275 (2%) Query: 7 VGADWLAEHIDDPE----IQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHT 62 V A W+AE + P +Q++DA P + R+ +E+ HIPGA FFDI+ SD T Sbjct: 21 VSAQWVAEALRAPRAGQPLQLLDASWYLP-KLGRDARREFEERHIPGAAFFDIDQCSDRT 79 Query: 63 SPLPHMLPRPETFAVAMRELGVNQDKHLIVYD--EGNLFSAPRAWWMLRTFGVEKVSILG 120 SP HMLP E FA LGV H+++YD + L+SAPR WWM R FG VS+L Sbjct: 80 SPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAFGHHAVSLLD 139 Query: 121 GGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARF 180 GGL W R +L L G + EF A +P + D+ Q++D+R RF Sbjct: 140 GGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQVVDSRATGRF 199 Query: 181 NAEVDEPRPGLRRGHIPGALNVPWTELV-REGELKTTDELDAIFFGRGVSYDKPIIVSCG 239 EPR G+ GHIPG +N+P+T+ + +EG K+ +E+ +F + V KP++ +CG Sbjct: 200 RGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDLSKPLVATCG 259 Query: 240 SGVTAAVVLLALATLDVPNVKLYDGAWSEWGARAD 274 SGVTA V L P+V +YDG+W EW RA Sbjct: 260 SGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRAR 294 >1BOH-A nrPDB Length = 296 Score = 319 bits (817), Expect = 1e-87, Method: Composition-based stats. Identities = 102/276 (36%), Positives = 140/276 (50%), Gaps = 10/276 (3%) Query: 6 FVGADWLAEHIDD----PEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 V WLAE + P ++++DA SPG R +EYL H+PGA FFDIE D Sbjct: 9 LVSTKWLAESVRAGKVGPGLRVLDASWYSPGT--REARKEYLERHVPGASFFDIEECRDK 66 Query: 62 TSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNL--FSAPRAWWMLRTFGVEKVSIL 119 SP MLP FA + LG++ D H++VYD +L F APR WWM R FG VS+L Sbjct: 67 ASPYEVMLPSEAGFADYVGSLGISNDTHVVVYDGDDLGSFYAPRVWWMFRVFGHRTVSVL 126 Query: 120 GGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAAR 179 GG W ++ + F A N + VL Q++D+R R Sbjct: 127 NGGFRNWLKEGHPVTSEPSRPEPAIFKATLNRSLLKTYEQVLENLESKRFQLVDSRAQGR 186 Query: 180 FNAEVDEPRP-GLRRGHIPGALNVPWTELVR-EGELKTTDELDAIFFGRGVSYDKPIIVS 237 + EP GL GHI G++N+P+ + +G K+ +EL A+F + V KP+I + Sbjct: 187 YLGTQPEPDAVGLDSGHIRGSVNMPFMNFLTEDGFEKSPEELRAMFEAKKVDLTKPLIAT 246 Query: 238 CGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARA 273 C GVTA + LA P+V +YDG+W EW RA Sbjct: 247 CRKGVTACHIALAAYLCGKPDVAIYDGSWFEWFHRA 282 >1UAR-A nrPDB Length = 285 Score = 312 bits (799), Expect = 1e-85, Method: Composition-based stats. Identities = 84/283 (29%), Positives = 137/283 (48%), Gaps = 22/283 (7%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V DW+ EH++DP++++++ D ++ Y GHIPGA D + D P+ Sbjct: 9 LVSTDWVQEHLEDPKVRVLEV--------DEDILL-YDTGHIPGAQKIDWQR--DFWDPV 57 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 E FA M LG++ D +++Y + N + A A+W + G + V ++ GG Sbjct: 58 VRDFISEEEFAKLMERLGISNDTTVVLYGDKNNWWAAYAFWFFKYNGHKDVRLMNGGRQK 117 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLAS----HENTAQIIDARPAARFN 181 W + L P G + + E++ D +L E ++D R + Sbjct: 118 WVEEGRPLTTEVPSYPPGRYEVPYRDESIRAYRDDVLEHIIKVKEGKGALVDVRSPQEYR 177 Query: 182 AEV----DEPRPG-LRRGHIPGALNVPWTELVR-EGELKTTDELDAIFFGRGVSYDKPII 235 E+ D P+ G LR GHIPGA N+PW + V +G K+ +EL A++ G++ DK I+ Sbjct: 178 GELTHMPDYPQEGALRAGHIPGAKNIPWAKAVNPDGTFKSAEELRALYEPLGITKDKDIV 237 Query: 236 VSCGSGVTAAVVLLALAT-LDVPNVKLYDGAWSEWGARADLPV 277 V C ++ L L P+VK YDG+W+EWG +P+ Sbjct: 238 VYCRIAERSSHSWFVLKYLLGYPHVKNYDGSWTEWGNLVGVPI 280 >3AAX-A nrPDB Length = 277 Score = 297 bits (759), Expect = 4e-81, Method: Composition-based stats. Identities = 79/280 (28%), Positives = 126/280 (45%), Gaps = 19/280 (6%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V ADW ++ P++ ++ ED + Y HI GA+ D +D P+ Sbjct: 7 LVSADWAESNLHAPKVVFVEV------DEDTSA---YDRDHIAGAIKLDWR--TDLQDPV 55 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 + F+ + E G+ + +I+Y N + A A+W + +G EKV +L GG Sbjct: 56 KRDFVDAQQFSKLLSERGIANEDTVILYGGNNNWFAAYAYWYFKLYGHEKVKLLDGGRKK 115 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVD 185 W+ D L V P + A+ + D +LA+ N +ID R F+ ++ Sbjct: 116 WELDGRPLSSDPVSRPVTSYTASPPDNTIRAFRDEVLAAI-NVKNLIDVRSPDEFSGKIL 174 Query: 186 EP-----RPGLRRGHIPGALNVPWTELVR-EGELKTTDELDAIFFGRGVSYDKPIIVSCG 239 P R GHIPGA+NVPW+ +G K+ +EL ++ G+ K I C Sbjct: 175 APAHLPQEQSQRPGHIPGAINVPWSRAANEDGTFKSDEELAKLYADAGLDNSKETIAYCR 234 Query: 240 SGVTAAVVLLALA-TLDVPNVKLYDGAWSEWGARADLPVE 278 G ++ L L NVK YDG+W+E+G+ P+E Sbjct: 235 IGERSSHTWFVLRELLGHQNVKNYDGSWTEYGSLVGAPIE 274 >3HZU-A nrPDB Length = 318 Score = 275 bits (703), Expect = 2e-74, Method: Composition-based stats. Identities = 78/286 (27%), Positives = 124/286 (43%), Gaps = 34/286 (11%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V ADWL+ H+ P + I+++ D +V Y GHIPGAV D +D P Sbjct: 41 LVTADWLSAHMGAPGLAIVES--------DEDVLL-YDVGHIPGAVKIDWH--TDLNDPR 89 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 E FA M G+ +D +++Y + + + A A W+ FG V +L GG Sbjct: 90 VRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYALWVFTLFGHADVRLLNGGRDL 149 Query: 126 WQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENT-------AQIIDARPAA 178 W E L P VV+ D + + + +ID R Sbjct: 150 WLA-----ERRETTLDVPTKTCTGYP--VVQRNDAPIRAFRDDVLAILGAQPLIDVRSPE 202 Query: 179 RFNAEV----DEPRPG-LRRGHIPGALNVPWTELVRE-GELKTTDELDAIFFGRGVSYDK 232 + + D P G LR GHIP A+++PW + E G ++ +EL+ ++ ++ D Sbjct: 203 EYTGKRTHMPDYPEEGALRAGHIPTAVHIPWGKAADESGRFRSREELERLY--DFINPDD 260 Query: 233 PIIVSCGSGVTAAVVLLALAT-LDVPNVKLYDGAWSEWGARADLPV 277 +V C G ++ L L +V+ YDG+W+EWG +P+ Sbjct: 261 QTVVYCRIGERSSHTWFVLTHLLGKADVRNYDGSWTEWGNAVRVPI 306 Score = 49.4 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 49/142 (34%), Gaps = 14/142 (9%) Query: 132 LLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGL 191 P +A +PE +V + I+ E DE Sbjct: 19 PGSMPLPADPSPTLSAYAHPERLVTADWLSAHMGAPGLAIV----------ESDEDVLLY 68 Query: 192 RRGHIPGALNVPWTELVREGELK---TTDELDAIFFGRGVSYDKPIIVSC-GSGVTAAVV 247 GHIPGA+ + W + + ++ ++ + +G++ D +++ S AA Sbjct: 69 DVGHIPGAVKIDWHTDLNDPRVRDYINGEQFAELMDRKGIARDDTVVIYGDKSNWWAAYA 128 Query: 248 LLALATLDVPNVKLYDGAWSEW 269 L +V+L +G W Sbjct: 129 LWVFTLFGHADVRLLNGGRDLW 150 >3P3A-A nrPDB Length = 320 Score = 270 bits (690), Expect = 5e-73, Method: Composition-based stats. Identities = 82/280 (29%), Positives = 119/280 (42%), Gaps = 22/280 (7%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 V ADWLA ++ P + I+++ D +V Y GHIPGAV D +D P Sbjct: 42 LVTADWLASNLGRPGLVIVES--------DEDVLL-YDTGHIPGAVKIDWH--TDLNDPA 90 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAG 125 E FA M GV +D +++Y + + + A A W+ FG V +L GG Sbjct: 91 VRDYINGEQFAALMDRKGVTRDDTVVIYGDKSNWWAAYAMWVFHLFGHPDVRLLDGGRDL 150 Query: 126 WQRDDLLLEEGAVELPEGEFN-AAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEV 184 W + N + D +L +ID R + E Sbjct: 151 WVSTGRDTTLEVPTRQTSGYPVVERNDAPIRAFKDDVLRVL-GKEPLIDVRSPQEYTGER 209 Query: 185 ----DEPRPG-LRRGHIPGALNVPWTELV-REGELKTTDELDAIFFGRGVSYDKPIIVSC 238 D P G LR GHIP A++VPW++ +G + EL+ I+ V D IV C Sbjct: 210 THMPDYPEEGALRGGHIPTAVSVPWSKAAYDDGRFRARAELEEIY--GFVKPDDKPIVYC 267 Query: 239 GSGVTAAVVLLAL-ATLDVPNVKLYDGAWSEWGARADLPV 277 G ++ L L PNV+ YDG+W+EWG +P+ Sbjct: 268 RIGERSSHTWFVLTYLLGHPNVRNYDGSWTEWGNAVRVPI 307 >1H4M-X nrPDB Length = 271 Score = 262 bits (669), Expect = 1e-70, Method: Composition-based stats. Identities = 75/258 (29%), Positives = 104/258 (40%), Gaps = 6/258 (2%) Query: 24 IDARMASPGQ--EDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRE 81 + AR+++P D A Y GHIPGA F D + P P + P E E Sbjct: 16 LQARLSAPELILVDLTSAARYAEGHIPGARFVDPKRTQLGQPPAPGLQPPREQLESLFGE 75 Query: 82 LGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELP 141 LG + +VYD+ A R W+L G ++ L GGL W +D L Sbjct: 76 LGHRPEAVYVVYDDEGGGWAGRFIWLLDVIGQQRYHYLNGGLTAWLAEDRPLSRELPAPA 135 Query: 142 EGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALN 201 G + + E +L I DAR + E G GHIPGA+N Sbjct: 136 GGPVALSLHDEPTASRDYLLGRLGAADLAIWDARSPQEYRGEKVLAAKG---GHIPGAVN 192 Query: 202 VPWTELVREGE-LKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVK 260 WT + L+ ++ G++ DK I+ C + + + L L P VK Sbjct: 193 FEWTAAMDPSRALRIRTDIAGRLEELGITPDKEIVTHCQTHHRSGLTYLIAKALGYPRVK 252 Query: 261 LYDGAWSEWGARADLPVE 278 Y G+W EWG D PVE Sbjct: 253 GYAGSWGEWGNHPDTPVE 270 >3UTN-X nrPDB Length = 327 Score = 254 bits (649), Expect = 3e-68, Method: Composition-based stats. Identities = 90/277 (32%), Positives = 127/277 (45%), Gaps = 26/277 (9%) Query: 20 EIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAM 79 I +DA P + N IP ++FFDI+A+SD SP PHM P + F AM Sbjct: 46 RIVPVDATWYLPSWKLDNKVDFLTKPRIPNSIFFDIDAISDKKSPYPHMFPTKKVFDDAM 105 Query: 80 RELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVE 139 LGV +D L+VYD FS+PR W L G KV +L ++ L+ V Sbjct: 106 SNLGVQKDDILVVYDRVGNFSSPRCAWTLGVMGHPKVYLLN-NFNQYREFKYPLDSSKVA 164 Query: 140 LPEGEFNAAFNPEAVVKVTDVLLASHENTAQII------------DARPAARFNAEVDEP 187 + + E+ D + +E Q++ DAR RF EP Sbjct: 165 AFSPYPKSHY--ESSESFQDKEIVDYEEMFQLVKSGELAKKFNAFDARSLGRFEGTEPEP 222 Query: 188 RPGLRRGHIPGALNVPWTELVREGELKTTDEL-DAIF---------FGRGVSYDKPIIVS 237 R + GHIPG +P+ L+ + E KT E +AI F + KP I S Sbjct: 223 RSDIPSGHIPGTQPLPYGSLL-DPETKTYPEAGEAIHATLEKALKDFHCTLDPSKPTICS 281 Query: 238 CGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARAD 274 CG+GV+ ++ AL VPNV+LYDG+W+EW ++ Sbjct: 282 CGTGVSGVIIKTALELAGVPNVRLYDGSWTEWVLKSG 318 >2WLX-A nrPDB Length = 423 Score = 238 bits (606), Expect = 3e-63, Method: Composition-based stats. Identities = 62/293 (21%), Positives = 115/293 (39%), Gaps = 34/293 (11%) Query: 6 FVGADWLAEHIDDPEI--------QIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEA 57 V WL + E+ ++I+A +P YL HIPGA + D Sbjct: 125 LVYPQWLHDLQQGKEVTAKPAGDWKVIEAAWGAPKL--------YLISHIPGADYIDTNE 176 Query: 58 LSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVS 117 + + PL + + E + + G+ D +I+Y ++++A R ++ GV+ V Sbjct: 177 V--ESEPLWNKV-SDEQLKAMLAKHGIRHDTTVILYGR-DVYAAARVAQIMLYAGVKDVR 232 Query: 118 ILGGGLAGWQRDDLLLEEGAV----ELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIID 173 +L GG W L +E G P+ P+ ++ + H A ++ Sbjct: 233 LLDGGWQTWSDAGLPVERGTPPKVKAEPDFGVKIPAQPQLMLDMEQARGLLHRQDASLVS 292 Query: 174 ARPAARFNAEVDEPR--------PGLRRGHIPGALNVPWTELVR-EGELKTTDELDAIFF 224 R F G R GH G+ + + +G +++ D++ A++ Sbjct: 293 IRSWPEFIGTTSGYSYIKPKGEIAGARWGHA-GSDSTHMEDFHNPDGTMRSADDITAMWK 351 Query: 225 GRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPV 277 + ++ + CG+G A+ + + NV +YDG W EW + PV Sbjct: 352 AWNIKPEQQVSFYCGTGWRASETFMYARAMGWKNVSVYDGGWYEWSSDPKNPV 404 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 44/222 (19%), Positives = 75/222 (33%), Gaps = 30/222 (13%) Query: 63 SPLPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGG 122 S E +++ + D + +Y A + + G Sbjct: 52 SASWLDKMSTEQLNAWIKQHNLKTDAPVALYGNDKDVDAVKT------------RLQKAG 99 Query: 123 LAGWQRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNA 182 L L E + F P+ + + + A+PA + Sbjct: 100 LTHISILSDALSEPSRLQKLPHFEQLVYPQWLHDLQQGKE---------VTAKPAGDW-- 148 Query: 183 EVDEPRPGLRR----GHIPGALNVPWTELVREGELK--TTDELDAIFFGRGVSYDKPIIV 236 +V E G + HIPGA + E+ E + ++L A+ G+ +D +I+ Sbjct: 149 KVIEAAWGAPKLYLISHIPGADYIDTNEVESEPLWNKVSDEQLKAMLAKHGIRHDTTVIL 208 Query: 237 SCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPVE 278 AA V + V +V+L DG W W + A LPVE Sbjct: 209 YGRDVYAAARVAQIMLYAGVKDVRLLDGGWQTW-SDAGLPVE 249 >1OKG-A nrPDB Length = 373 Score = 237 bits (603), Expect = 6e-63, Method: Composition-based stats. Identities = 78/290 (26%), Positives = 125/290 (43%), Gaps = 30/290 (10%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSD---HT 62 F+ +A+H+ E +I+D R + ++ ++ +Y H+ A+ D++ T Sbjct: 15 FLDPSEVADHL--AEYRIVDCRYSLKIKDHGSI--QYAKEHVKSAIRADVDTNLSKLVPT 70 Query: 63 SPLPHMLPRPETFAVAMRELGVNQDKHLIVYDE-GNLFSAPRAWWMLRTFGVEKVSILGG 121 S H LP F G+ + ++ YD+ R WWML + G + ++ G Sbjct: 71 STARHPLPPCAEFIDWCMANGMAGELPVLCYDDECGAMGGCRLWWMLNSLGADAY-VING 129 Query: 122 GLAGWQRDDLLLEEG-AVELPEG----EFNAAFNPEAVVKVTDVLLASHENTAQIIDARP 176 G + L +E G LP F AF +V A I DAR Sbjct: 130 GFQACKAAGLEMESGEPSSLPRPATHWPFKTAFQHHYLVDEI-------PPQAIITDARS 182 Query: 177 AARFNAEVDEPRPGLRRGHIPGALNVPWT-ELVREGE---LKTTDELDA----IFFGRGV 228 A RF + V GHI GA N+P+T LV G+ L++ +E+ + G G Sbjct: 183 ADRFASTVRPYAADKMPGHIEGARNLPYTSHLVTRGDGKVLRSEEEIRHNIMTVVQGAGD 242 Query: 229 SYD-KPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARADLPV 277 + D + SCGSGVTA + + + L + + LY G+WSE+ P+ Sbjct: 243 AADLSSFVFSCGSGVTACINIALVHHLGLGHPYLYCGSWSEYSGLFRPPI 292 >2EG4-A nrPDB Length = 230 Score = 169 bits (428), Expect = 1e-42, Method: Composition-based stats. Identities = 62/250 (24%), Positives = 90/250 (36%), Gaps = 31/250 (12%) Query: 33 QEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLPHMLPRPETFAVAMRELGVNQDKHLIV 92 D Y GH+PGA D+ A + + LG+ +++ Sbjct: 9 LVDTRPRPAYEAGHLPGARHLDLSAPKLRLREEAELKALEGGLTELFQTLGLRSP--VVL 66 Query: 93 YDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEGAVELPEGEFNAAFNPE 152 YDEG R + L G+E V + GW+ EE E E Sbjct: 67 YDEGLTSRLCRTAFFLGLGGLE-VQLW---TEGWEPYATEKEEPKPE----------RTE 112 Query: 153 AVVK-VTDVLLASHENTAQ--IIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVR 209 V K D LL + E ++D R F +V P R G IPG+ N P + Sbjct: 113 VVAKLRRDWLLTADEAARHPLLLDVRSPEEFQGKVHPP-CCPRGGRIPGSKNAPLELFLS 171 Query: 210 EGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW 269 + + G+ + + V C SG +AV L +L V + Y G+ EW Sbjct: 172 P---------EGLLERLGLQPGQEVGVYCHSGARSAVAFFVLRSLGV-RARNYLGSMHEW 221 Query: 270 GARADLPVEP 279 + LP EP Sbjct: 222 -LQEGLPTEP 230 >1TQ1-A nrPDB Length = 129 Score = 106 bits (265), Expect = 9e-24, Method: Composition-based stats. Identities = 37/126 (29%), Positives = 50/126 (39%), Gaps = 18/126 (14%) Query: 153 AVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGE 212 +V D+LLA H +D R F+ +GH GA+NVP+ G Sbjct: 21 SVTVAHDLLLAGHR----YLDVRTPEEFS-----------QGHACGAINVPYMNRGASGM 65 Query: 213 LKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGAR 272 K TD L+ + G IIV C SG + L VK G +S W A+ Sbjct: 66 SKNTDFLEQVSSHFG--QSDNIIVGCQSGGRSIKATTDLLHAGFTGVKDIVGGYSAW-AK 122 Query: 273 ADLPVE 278 LP + Sbjct: 123 NGLPTK 128 >1YT8-A nrPDB Length = 539 Score = 64.8 bits (156), Expect = 4e-11, Method: Composition-based stats. Identities = 38/178 (21%), Positives = 59/178 (33%), Gaps = 27/178 (15%) Query: 85 NQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRDDLLLEEG---AVELP 141 +D + VYD+G AP A L G V++L GGL+GW+ L + Sbjct: 61 RRDTPITVYDDGEGL-APVAAQRLHDLGYSDVALLDGGLSGWRNAGGELFRDVNVPSKAF 119 Query: 142 EGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALN 201 A + ++ L A I+DAR + IPG ++ Sbjct: 120 GELVEAERHTPSLAAEEVQALLDARAEAVILDARRFDEYQTMS-----------IPGGIS 168 Query: 202 VPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNV 259 VP EL +IV+C + + +L +PN Sbjct: 169 VP------------GAELVLRVAELAPDPRTRVIVNCAGRTRSIIGTQSLLNAGIPNP 214 Score = 48.7 bits (114), Expect = 3e-06, Method: Composition-based stats. Identities = 27/145 (18%), Positives = 46/145 (31%), Gaps = 30/145 (20%) Query: 7 VGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPLP 66 + LA+ + +P +++D + Y HIPGA + Sbjct: 379 IDPTTLADWLGEPGTRVLDFT----------ASANYAKRHIPGAAWV------------- 415 Query: 67 HMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGW 126 A+ LG + L G+ A A ++ + V +L GG + W Sbjct: 416 ----LRSQLKQALERLGTAERYVLTC---GSSLLARFAVAEVQALSGKPVFLLDGGTSAW 468 Query: 127 QRDDLLLEEGAVELPEGEFNAAFNP 151 L E+G L + P Sbjct: 469 VAAGLPTEDGESLLASPRIDRYRRP 493 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 57/275 (20%), Positives = 90/275 (32%), Gaps = 58/275 (21%) Query: 6 FVGADWLAEHIDDPEIQ-IIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSP 64 V A+ + E+Q ++DAR + + R EY IPG + Sbjct: 122 LVEAERHTPSLAAEEVQALLDARAEAVILDARR-FDEYQTMSIPGGISV----------- 169 Query: 65 LPHMLPRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLA 124 + + EL + +IV G S +L V+ L G Sbjct: 170 ------PGAELVLRVAELAPDPRTRVIVNCAGRTRSIIGTQSLLNAGIPNPVAALRNGTI 223 Query: 125 GWQRDDLLLEEGAVEL----------PEGEFNAAFNPEAVVKVTDVLLAS-----HENTA 169 GW LE G + A A V+ D+ + H+ T Sbjct: 224 GWTLAGQQLEHGQTRRFGAISQDTRKAAAQRARAVADRAGVERLDLAGLAQWQDEHDRTT 283 Query: 170 QIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVS 229 ++D R + GH+PG+ + P +LV+E TD + ++ R V Sbjct: 284 YLLDVRTPEEY-----------EAGHLPGSRSTPGGQLVQE-----TDHVASVRGARLVL 327 Query: 230 YDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDG 264 D GV A + LA + V + DG Sbjct: 328 VDDD-------GVRANMSASWLAQMGWQ-VAVLDG 354 Score = 27.9 bits (60), Expect = 5.7, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 20/68 (29%), Gaps = 4/68 (5%) Query: 207 LVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAW 266 + E+ A R D PI V A V L L +V L DG Sbjct: 43 AANLPLSRLELEIHARVPRR----DTPITVYDDGEGLAPVAAQRLHDLGYSDVALLDGGL 98 Query: 267 SEWGARAD 274 S W Sbjct: 99 SGWRNAGG 106 >6BEV-A nrPDB Length = 135 Score = 63.7 bits (153), Expect = 9e-11, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 38/118 (32%), Gaps = 13/118 (11%) Query: 153 AVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGE 212 V + ++ A++ D R G IPGALN+P +EL Sbjct: 25 PTVSLPELRSLLASGRARLFDVRSREE-----------AAAGTIPGALNIPVSEL-ESAL 72 Query: 213 LKTTDELDAIFFGRGVSYDKP-IIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW 269 A++ + ++ C G +L + Y GA+ EW Sbjct: 73 QMEPAAFQALYSAEKPKLEDEHLVFFCQMGKRGLQATQLARSLGYTGARNYAGAYREW 130 >3D1P-A nrPDB Length = 139 Score = 62.9 bits (151), Expect = 2e-10, Method: Composition-based stats. Identities = 20/110 (18%), Positives = 38/110 (34%), Gaps = 12/110 (10%) Query: 165 HENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFF 224 H+ ++D R + ++ HIP ++NVP+ + E + Sbjct: 37 HDPNVVLVDVREPSEYSIV-----------HIPASINVPY-RSHPDAFALDPLEFEKQIG 84 Query: 225 GRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEWGARAD 274 K +I C SG ++ N LY G+ ++W + Sbjct: 85 IPKPDSAKELIFYCASGKRGGEAQKVASSHGYSNTSLYPGSMNDWVSHGG 134 >3ICS-A nrPDB Length = 588 Score = 47.1 bits (110), Expect = 8e-06, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 44/146 (30%), Gaps = 28/146 (19%) Query: 127 QRDDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLL--ASHENTAQIIDARPAARFNAEV 184 + + A+ + V EN +ID R Sbjct: 460 LSYAPPYSSAKDPVNMVGYAASNIVDGFVDTVQWHEIDRIVENGGYLIDVREPNE----- 514 Query: 185 DEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCGSGVTA 244 L++G I G++N+P DEL V DK I ++C G+ Sbjct: 515 ------LKQGMIKGSINIPL------------DELRDRLEE--VPVDKDIYITCQLGMRG 554 Query: 245 AVVLLALATLDVPNVKLYDGAWSEWG 270 V L VK DG + +G Sbjct: 555 YVAARMLMEKGYK-VKNVDGGFKLYG 579 >2JTQ-A nrPDB Length = 85 Score = 44.0 bits (102), Expect = 8e-05, Method: Composition-based stats. Identities = 16/97 (16%), Positives = 30/97 (30%), Gaps = 23/97 (23%) Query: 168 TAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRG 227 ID R ++ E H+ GA+N+P E+ Sbjct: 1 AEHWIDVRVPEQYQQE-----------HVQGAINIPL------------KEVKERIATAV 37 Query: 228 VSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDG 264 + + V C +G + L+ + +V+ G Sbjct: 38 PDKNDTVKVYCNAGRQSGQAKEILSEMGYTHVENAGG 74 >3NTA-A nrPDB Length = 574 Score = 42.5 bits (98), Expect = 2e-04, Method: Composition-based stats. Identities = 20/104 (19%), Positives = 32/104 (30%), Gaps = 26/104 (25%) Query: 166 ENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFG 225 ++D R L+ G + GA+N+P DEL Sbjct: 484 SEDQLLLDVRNPGE-----------LQNGGLEGAVNIP------------VDELRDRMHE 520 Query: 226 RGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW 269 + DK II+ C G+ V L + G + + Sbjct: 521 --LPKDKEIIIFCQVGLRGNVAYRQLVNNGY-RARNLIGGYRTY 561 >1QB0-A nrPDB Length = 211 Score = 40.6 bits (93), Expect = 9e-04, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 43/143 (30%), Gaps = 28/143 (19%) Query: 148 AFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTEL 207 +PE +V + ++ + I+D R + GHI A+N+P Sbjct: 45 YISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEG-----------GHIKTAVNLPLERD 93 Query: 208 VREGELKTTDELDAIFFGRGVSYDKPIIVSC----GSGVTAA-------VVLLALATLDV 256 LK+ + +I C G + +L Sbjct: 94 AESFLLKSP------IAPCSLDKRVILIFHCEFSSERGPRMCRFIRERDRAVNDYPSLYY 147 Query: 257 PNVKLYDGAWSEWGARADLPVEP 279 P + + G + E+ + EP Sbjct: 148 PEMYILKGGYKEFFPQHPNFCEP 170 >1C25-A nrPDB Length = 161 Score = 39.4 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 44/147 (29%), Gaps = 37/147 (25%) Query: 148 AFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTEL 207 +PE + V + A+ IID R + GHI GA+N+ E Sbjct: 24 YISPEIMASVLNGKFANLIKEFVIIDCRYPYEYEG-----------GHIKGAVNLHMEEE 72 Query: 208 VREGELKTTDELDAIFFGRGVSYDKP----IIVSCG-SGVTAAVVLLALAT--------- 253 V + LK + ++ C S + + Sbjct: 73 VEDFLLKKP-----------IVPTDGKRVIVVFHCEFSSERGPRMCRYVRERDRLGNEYP 121 Query: 254 -LDVPNVKLYDGAWSEWGARADLPVEP 279 L P + + G + E+ + EP Sbjct: 122 KLHYPELYVLKGGYKEFFMKCQSYCEP 148 >4WH9-A nrPDB Length = 183 Score = 37.5 bits (85), Expect = 0.007, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 25/69 (36%), Gaps = 11/69 (15%) Query: 148 AFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTEL 207 +PE +V + ++ + I+D R + GHI A+N+P Sbjct: 32 YISPETMVALLTGKFSNIVDKFVIVDCRYPYEYEG-----------GHIKTAVNLPLERD 80 Query: 208 VREGELKTT 216 LK+ Sbjct: 81 AESFLLKSP 89 >1GN0-A nrPDB Length = 108 Score = 35.9 bits (81), Expect = 0.018, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 30/111 (27%), Gaps = 25/111 (22%) Query: 159 DVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTELVREGELKTTDE 218 D E A ++D R F GH A T ++ D Sbjct: 11 DAHQKLQEKEAVLVDIRDPQSFA-----------MGHAVQA--FHLTNDTLGAFMRDNDF 57 Query: 219 LDAIFFGRGVSYDKPIIVSCGSGVTAAVVLLALATLDVPNVKLYDGAWSEW 269 D P++V C G ++ L V DG + W Sbjct: 58 ------------DTPVMVMCYHGNSSKGAAQYLLQQGYDVVYSIDGGFEAW 96 Score = 31.3 bits (69), Expect = 0.44, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 21/60 (35%), Gaps = 3/60 (5%) Query: 70 PRPETFAVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSILGGGLAGWQRD 129 +T MR+ + ++ Y + A L G + V + GG WQR Sbjct: 43 LTNDTLGAFMRDNDFDTPVMVMCYHGNSSKGAA---QYLLQQGYDVVYSIDGGFEAWQRQ 99 >1T3K-A nrPDB Length = 152 Score = 32.9 bits (73), Expect = 0.16, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 47/137 (34%), Gaps = 24/137 (17%) Query: 2 STTWFVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDH 61 S ++ L H P I IID R + + Y GHI G++ + + D Sbjct: 26 SISYITSTQLLPLH-RRPNIAIIDVR---------DEERNYD-GHIAGSLHYASGSFDDK 74 Query: 62 TSPLPHMLPRPETF---AVAMRELGVNQDKHLIVYDEGNLFSAPRAWWMLRTFGVEKVSI 118 S L + +T + + G + L+ Y + G++ + I Sbjct: 75 ISHLVQNVKDKDTLVFHSALSQVRGPTCARRLVNYLDEKK----------EDTGIKNIMI 124 Query: 119 LGGGLAGWQRDDLLLEE 135 L G GW+ + Sbjct: 125 LERGFNGWEASGKPVCR 141 >3OP3-A nrPDB Length = 216 Score = 31.3 bits (69), Expect = 0.46, Method: Composition-based stats. Identities = 20/96 (20%), Positives = 28/96 (29%), Gaps = 27/96 (28%) Query: 148 AFNPEAVVKVTDVLLASHENTAQIIDARPAARFNAEVDEPRPGLRRGHIPGALNVPWTEL 207 NPE V + +ID R + GHI GALN Sbjct: 58 YVNPETVAALLSGKFQGLIEKFYVIDCRYPYEYLG-----------GHIQGALN------ 100 Query: 208 VREGELKTTDELDAIFFGRGVSYDKP-----IIVSC 238 L + +EL F + + I+ C Sbjct: 101 -----LYSQEELFNFFLKKPIVPLDTQKRIIIVFHC 131 >2J13-A nrPDB Length = 247 Score = 31.3 bits (69), Expect = 0.50, Method: Composition-based stats. Identities = 12/71 (16%), Positives = 22/71 (30%), Gaps = 2/71 (2%) Query: 191 LRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIVSCG--SGVTAAVVL 248 GHI G + + + K +EL ++ + + GV + L Sbjct: 104 KDEGHIIGNHSWSHPDFTAVNDEKLREELTSVTEEIKKVTGQKEVKYVRPPRGVFSERTL 163 Query: 249 LALATLDVPNV 259 + NV Sbjct: 164 ALTKEMGYYNV 174 >2VSW-A nrPDB Length = 153 Score = 30.6 bits (67), Expect = 0.74, Method: Composition-based stats. Identities = 27/151 (17%), Positives = 51/151 (33%), Gaps = 11/151 (7%) Query: 6 FVGADWLAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEALSDHTSPL 65 +G + E + + ++++ D EY HI A+ + L Sbjct: 1 MIGTQIVTERL----VALLESGTEKVLLIDSRPFVEYNTSHILEAININCSKLMKRRLQQ 56 Query: 66 PHMLPRPETFAVAMRELGVNQDKHLIVYDEG-----NLFSAPRAWWMLRTF--GVEKVSI 118 +L A ++ ++ + ++VYD+ +L S +L V + Sbjct: 57 DKVLITELIQHSAKHKVDIDCSQKVVVYDQSSQDVASLSSDCFLTVLLGKLEKSFNSVHL 116 Query: 119 LGGGLAGWQRDDLLLEEGAVELPEGEFNAAF 149 L GG A + R L EG L + Sbjct: 117 LAGGFAEFSRCFPGLCEGKSTLVPTCISQPA 147 >4CMR-A nrPDB Length = 597 Score = 30.6 bits (67), Expect = 0.83, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 29/86 (33%), Gaps = 13/86 (15%) Query: 122 GLAGWQR-DDLLLEEGAVELPEGEFNAAFNPEAVVKVTDVLLASHENTAQIIDARPAARF 180 GL GW+ + E E+P ++N V D+ + +ID Sbjct: 514 GLEGWETTEKAWFESLRSEVPNSKYNVVTRAALYVGKRDLP----PDMRSVIDT------ 563 Query: 181 NAEVDEPRPGLRRGHIPGALNVPWTE 206 D GHIPG ++ W Sbjct: 564 --LYDLEEAVPDTGHIPGEMHGKWEN 587 >5ND4-A nrPDB Length = 412 Score = 30.2 bits (66), Expect = 1.0, Method: Composition-based stats. Identities = 14/65 (21%), Positives = 23/65 (35%), Gaps = 7/65 (10%) Query: 12 LAEHIDDPEIQIIDARMASPGQEDRNVAQEYLNGHIPGAVFFDIEAL---SDHTSPLPHM 68 ++ H+ +QI +A E GH+P AVF D+E T + Sbjct: 4 ISIHVGQAGVQIGNACWELYCLEHGIQPD----GHVPRAVFVDLEPTVIDEVRTGTYRQL 59 Query: 69 LPRPE 73 + Sbjct: 60 FHPEQ 64 >2Q9V-A nrPDB Length = 90 Score = 29.8 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 22/51 (43%), Gaps = 5/51 (9%) Query: 186 EPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIV 236 EP + GHI VP +G L++ DEL ++ + ++V Sbjct: 24 EPGEPIYIGHI-----VPLGAADTDGRLRSGDELISVDGTPVIGKSHQLVV 69 >5ZYS-A nrPDB Length = 97 Score = 28.6 bits (62), Expect = 2.9, Method: Composition-based stats. Identities = 13/51 (25%), Positives = 21/51 (41%), Gaps = 5/51 (9%) Query: 186 EPRPGLRRGHIPGALNVPWTELVREGELKTTDELDAIFFGRGVSYDKPIIV 236 EP + GHI VP +G L++ DEL + + ++V Sbjct: 31 EPGEPIYIGHI-----VPLGAADTDGRLRSGDELICVDGTPVIGKSHQLVV 76 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.305 0.122 0.335 Lambda K H 0.267 0.0378 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,620,837 Number of Sequences: 36641 Number of extensions: 396733 Number of successful extensions: 1295 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 27 Number of HSP's that attempted gapping in prelim test: 1118 Number of HSP's gapped (non-prelim): 83 length of query: 281 length of database: 10,336,785 effective HSP length: 96 effective length of query: 185 effective length of database: 6,819,249 effective search space: 1261561065 effective search space used: 1261561065 T: 11 A: 40 X1: 16 ( 7.0 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 58 (27.1 bits)