BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P31016 (724 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2XKX-A nrPDB 1477 0.0 4WSI-A nrPDB 182 4e-46 3TSW-A nrPDB 136 3e-32 3SHW-A nrPDB 135 7e-32 4F4J-A nrPDB 105 5e-23 1LVG-A nrPDB 105 8e-23 3LH5-A nrPDB 96 5e-20 3KFV-A nrPDB 87 2e-17 2QOR-A nrPDB 81 2e-15 6MFU-A nrPDB 79 1e-14 1Z6G-A nrPDB 76 5e-14 2QT5-A nrPDB 69 8e-12 2J41-A nrPDB 65 7e-11 5ZDS-A nrPDB 64 2e-10 4OEP-A nrPDB 60 3e-09 1WFV-A nrPDB 60 3e-09 1P1D-A nrPDB 60 5e-09 2R4H-A nrPDB 59 6e-09 3TSV-A nrPDB 58 2e-08 3TAU-A nrPDB 57 3e-08 3SHU-A nrPDB 56 7e-08 1UEQ-A nrPDB 55 8e-08 1UEZ-A nrPDB 55 1e-07 3EGH-C nrPDB 55 2e-07 3FY5-A nrPDB 54 2e-07 4Q2Q-A nrPDB 54 2e-07 2JIL-A nrPDB 54 3e-07 2DC2-A nrPDB 54 3e-07 3CBX-A nrPDB 54 3e-07 4JOF-A nrPDB 54 3e-07 2MX6-A nrPDB 53 4e-07 2LOB-A nrPDB 53 4e-07 3SUZ-A nrPDB 53 5e-07 2Q9V-A nrPDB 52 8e-07 1MFG-A nrPDB 51 2e-06 5ZYS-A nrPDB 51 2e-06 1U3B-A nrPDB 50 3e-06 4QL6-A nrPDB 50 3e-06 3CH8-A nrPDB 50 3e-06 4DEX-A nrPDB 50 3e-06 2VZ5-A nrPDB 50 3e-06 2QBW-A nrPDB 50 4e-06 2L4S-A nrPDB 50 4e-06 2F3T-A nrPDB 50 4e-06 3K1R-A nrPDB 49 8e-06 2KBS-A nrPDB 49 8e-06 3LNC-A nrPDB 48 2e-05 1X5N-A nrPDB 47 3e-05 1UEW-A nrPDB 47 4e-05 1S4Q-A nrPDB 47 4e-05 3TR0-A nrPDB 46 6e-05 4ZW2-A nrPDB 45 8e-05 1X6D-A nrPDB 45 9e-05 1UEP-A nrPDB 45 1e-04 3QDO-A nrPDB 45 1e-04 1N7E-A nrPDB 44 2e-04 5A2P-A nrPDB 44 3e-04 5G1D-A nrPDB 44 3e-04 1VYT-A nrPDB 43 4e-04 1GCQ-A nrPDB 43 4e-04 5N7D-A nrPDB 43 4e-04 1GRI-A nrPDB 43 5e-04 1NF3-C nrPDB 43 6e-04 1UJD-A nrPDB 42 9e-04 1UF1-A nrPDB 41 0.002 2LC7-A nrPDB 40 0.003 1RY4-A nrPDB 40 0.004 2EYZ-A nrPDB 40 0.005 1VYV-A nrPDB 40 0.005 2LQW-A nrPDB 40 0.005 1ZUB-A nrPDB 39 0.007 1U37-A nrPDB 39 0.007 2V90-A nrPDB 39 0.012 2EDP-A nrPDB 38 0.013 1WFG-A nrPDB 38 0.018 3PV2-A nrPDB 38 0.018 1VA8-A nrPDB 38 0.020 4UU6-A nrPDB 37 0.024 1P1E-A nrPDB 37 0.030 1V5Q-A nrPDB 37 0.031 3PV4-A nrPDB 37 0.039 1T0J-A nrPDB 37 0.041 1UJV-A nrPDB 37 0.042 5E6P-B nrPDB 36 0.051 2DLS-A nrPDB 36 0.053 1X5R-A nrPDB 35 0.090 1M5Z-A nrPDB 35 0.090 2PZ1-A nrPDB 35 0.095 4YNN-A nrPDB 35 0.11 1UFX-A nrPDB 35 0.13 4YO1-A nrPDB 35 0.17 1V6B-A nrPDB 34 0.18 2YT7-A nrPDB 34 0.27 2H8H-A nrPDB 33 0.30 6F3F-A nrPDB 33 0.36 3SOE-A nrPDB 33 0.36 5GJW-B nrPDB 33 0.38 4D25-A nrPDB 33 0.59 3BPU-A nrPDB 32 0.71 5MV8-B nrPDB 32 1.2 2X3W-D nrPDB 32 1.4 4MT6-A nrPDB 31 1.8 4N78-F nrPDB 31 2.2 2EAQ-A nrPDB 31 2.3 2KJP-A nrPDB 31 2.3 2NUP-C nrPDB 31 2.4 2QKW-B nrPDB 30 2.6 1K4U-S nrPDB 30 2.6 5T69-A nrPDB 30 2.9 3GF9-A nrPDB 30 3.1 4BNE-A nrPDB 30 3.6 1R6J-A nrPDB 30 3.8 5KZT-A nrPDB 29 5.7 3CYY-A nrPDB 29 5.8 5WQL-C nrPDB 29 6.0 3LA8-A nrPDB 29 6.3 4Q4L-A nrPDB 29 6.9 >2XKX-A nrPDB Length = 721 Score = 1477 bits (3824), Expect = 0.0, Method: Compositional matrix adjust. Identities = 718/724 (99%), Positives = 720/724 (99%), Gaps = 3/724 (0%) Query: 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE 60 MDCLCIVT KKYRYQDEDTPPL+HSPAHLPNQANSPPVIVNTDTLEAPGY VNGTEGE Sbjct: 1 MDCLCIVTAKKYRYQDEDTPPLKHSPAHLPNQANSPPVIVNTDTLEAPGY---VNGTEGE 57 Query: 61 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV Sbjct: 58 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 117 Query: 121 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN 180 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN Sbjct: 118 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN 177 Query: 181 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY 240 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY Sbjct: 178 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY 237 Query: 241 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 300 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD Sbjct: 238 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 297 Query: 301 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL 360 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL Sbjct: 298 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL 357 Query: 361 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT 420 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT Sbjct: 358 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT 417 Query: 421 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDS 480 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDS Sbjct: 418 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDS 477 Query: 481 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL 540 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL Sbjct: 478 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL 537 Query: 541 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE 600 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI+AHKFIE Sbjct: 538 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIRAHKFIE 597 Query: 601 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE 660 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE Sbjct: 598 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE 657 Query: 661 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 720 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA Sbjct: 658 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 717 Query: 721 RERL 724 RERL Sbjct: 718 RERL 721 >4WSI-A nrPDB Length = 394 Score = 182 bits (463), Expect = 4e-46, Method: Compositional matrix adjust. Identities = 125/404 (30%), Positives = 191/404 (47%), Gaps = 75/404 (18%) Query: 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTII---- 389 + + IS I+ GG A+ SG L +GD++L +NG+++R + L + T+T + Sbjct: 45 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 104 Query: 390 AQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKD----C 445 Q KP E IH ++A FDYD + D C Sbjct: 105 QQIKPPPAK--ETVIH---------------------------VKAHFDYDPSDDPYVPC 135 Query: 446 GFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAK 505 L LSF+ GD+LHVI D WWQA R + G +P K Sbjct: 136 REL--GLSFQKGDILHVISQEDPNWWQAYREGDEDNQPLAGLVPGK-------------- 179 Query: 506 DWGSSSGSQGREDSVLSYETVT--QMEVHYARPIIILGPTKDRAND---DLLSEFPDKFG 560 + +L+YE ++ + RPII++GP N+ L+++ D+F Sbjct: 180 ------------EEILTYEEMSLYHQPANRKRPIILIGPQNCGQNELRQRLMNKEKDRFA 227 Query: 561 SCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVA 620 S VPHTTR +R+ E+ GRDYHFVS R+ E DI A KFIE G++ +LYGTS+ SVR+V Sbjct: 228 SAVPHTTRSRRDQEVAGRDYHFVS-RQAFEADIAAGKFIEHGEFEKNLYGTSIDSVRQVI 286 Query: 621 EQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEI----NKRITEEQARKAFDR 676 GK C+L + +++ L+ + L P IFI P S E + + K E+ R+ ++ Sbjct: 287 NSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLRALLAKEGKNPKPEELREIIEK 346 Query: 677 ATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 720 ++EQ F + ++ Y ++ R+I L WVP+ Sbjct: 347 TREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEPQWVPS 390 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 17/58 (29%), Positives = 34/58 (58%), Gaps = 4/58 (6%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +K+++ K + V N+ +S+ +++I++GGAA K G L GD++L +N + Sbjct: 23 VKIVRIEKARDIPLGATVRNEM----DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 76 >3TSW-A nrPDB Length = 391 Score = 136 bits (342), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 123/449 (27%), Positives = 189/449 (42%), Gaps = 94/449 (20%) Query: 303 GEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSV 362 G I R ++V R +G + GG D GIF++ +L PA G L +GDQIL V Sbjct: 1 GSHMILRPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRV 58 Query: 363 NGVDLRNASHEQAAIALKN--AGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT 420 N VD N E+A + L + G+ VTI+AQ K + Y R ++ S +G Sbjct: 59 NNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRR-----------IVESDVGDS- 106 Query: 421 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA---GDEEWWQARRVH 477 FYIR F+Y+K G LSF G+V V+D G W A R+ Sbjct: 107 ----------FYIRTHFEYEKESPYG-----LSFNKGEVFRVVDTLYNGKLGSWLAIRIG 151 Query: 478 SDSETDDIGFIPSKRRVE----------------RREWSRLKAKDWGSSSGSQGRED--- 518 + + + G IP+K R E R ++ R + + + RED Sbjct: 152 KNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSA 211 Query: 519 -----SVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREY 573 +YE V E + RP+ I GP D A + L E PD Y Sbjct: 212 QPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDI--------------Y 257 Query: 574 EIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSAN 633 +I + + ++ I+ H +++++ +Q KH +LDV+ N Sbjct: 258 QIAKSEPRDAGTDQRSSGIIRLH------------------TIKQIIDQDKHALLDVTPN 299 Query: 634 AVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEE---QARKAFDRATKLEQEFTECFSA 690 AV RL A +PI +F+ P S + V + R+ E ARK ++R+ KL + F+ Sbjct: 300 AVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTT 359 Query: 691 IVEGDSFEE-IYHKVKRVIEDLSGPYIWV 718 + +S + Y +K I+ +WV Sbjct: 360 TINLNSMNDGWYGALKEAIQQQQNQLVWV 388 Score = 42.4 bits (98), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 10/74 (13%) Query: 161 IKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+V Sbjct: 10 MKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNV 61 Query: 219 GLEDVMHEDAVAAL 232 +++ E+AV L Sbjct: 62 DFTNIIREEAVLFL 75 Score = 33.1 bits (74), Expect = 0.43, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +G+S +G +AGG +D IF+ ++ AA++G L D IL VN VD Sbjct: 13 VKFRKGDS-VGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDF 63 Query: 126 REVTHSAAVEALKE--AGSIVRLYVMRRKPPAEKVME 160 + AV L + G V + ++K +++E Sbjct: 64 TNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVE 100 >3SHW-A nrPDB Length = 468 Score = 135 bits (340), Expect = 7e-32, Method: Compositional matrix adjust. Identities = 120/439 (27%), Positives = 186/439 (42%), Gaps = 94/439 (21%) Query: 313 RIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 ++V R +G + GG D GIF++ +L PA G L +GDQIL VN VD N Sbjct: 3 KLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNIIR 60 Query: 373 EQAAIALKN--AGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRG 430 E+A + L + G+ VTI+AQ K + Y R ++ S +G Sbjct: 61 EEAVLFLLDLPKGEEVTILAQKKKDVYRR-----------IVESDVGDS----------- 98 Query: 431 FYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA---GDEEWWQARRVHSDSETDDIGF 487 FYIR F+Y+K G LSF G+V V+D G W A R+ + + + G Sbjct: 99 FYIRTHFEYEKESPYG-----LSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGI 153 Query: 488 IPSKRRVE----------------RREWSRLKAKDWGSSSGSQGRED--------SVLSY 523 IP+K R E R ++ R + + + RED +Y Sbjct: 154 IPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFPAY 213 Query: 524 ETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFV 583 E V E + RP+ I GP D A + L E PD Y+I + Sbjct: 214 ERVVLREAGFLRPVTIFGPIADVAREKLAREEPDI--------------YQIAKSEPRDA 259 Query: 584 SSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHL 643 + ++ I+ H +++++ +Q KH +LDV+ NAV RL A Sbjct: 260 GTDQRSSGIIRLH------------------TIKQIIDQDKHALLDVTPNAVDRLNYAQW 301 Query: 644 HPIAIFIRPRSLENVLEINKRITEE---QARKAFDRATKLEQEFTECFSAIVEGDSFEE- 699 +PI +F+ P S + V + R+ E ARK ++R+ KL + F+ + +S + Sbjct: 302 YPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDG 361 Query: 700 IYHKVKRVIEDLSGPYIWV 718 Y +K I+ +WV Sbjct: 362 WYGALKEAIQQQQNQLVWV 380 Score = 42.7 bits (99), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 10/74 (13%) Query: 161 IKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+V Sbjct: 2 MKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNV 53 Query: 219 GLEDVMHEDAVAAL 232 +++ E+AV L Sbjct: 54 DFTNIIREEAVLFL 67 Score = 33.5 bits (75), Expect = 0.34, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +G+S +G +AGG +D IF+ ++ AA++G L D IL VN VD Sbjct: 5 VKFRKGDS-VGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDF 55 Query: 126 REVTHSAAVEALKE--AGSIVRLYVMRRKPPAEKVME 160 + AV L + G V + ++K +++E Sbjct: 56 TNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVE 92 >4F4J-A nrPDB Length = 202 Score = 105 bits (263), Expect = 5e-23, Method: Compositional matrix adjust. Identities = 66/191 (34%), Positives = 106/191 (55%), Gaps = 25/191 (13%) Query: 534 ARPIIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKME 590 +RPI+I GP+ K L +E+PD FG VP TTR R E++G+DY+FVS E + Sbjct: 17 SRPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVPSTTRTPRAGEVNGKDYNFVSVDE-FK 75 Query: 591 KDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQA-AHLHPIAIF 649 I+ ++FIE Q++ + YG++V SV++V++ GK CILD+ V+ ++A L+ +F Sbjct: 76 SMIKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNARFLF 135 Query: 650 IRPRSLENV---LE---------INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSF 697 I P S+E++ LE INKR++ QA A+ T ++ D Sbjct: 136 IAPPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYAE--------TGAHDKVIVNDDL 187 Query: 698 EEIYHKVKRVI 708 ++ Y ++K I Sbjct: 188 DKAYKELKDFI 198 >1LVG-A nrPDB Length = 198 Score = 105 bits (261), Expect = 8e-23, Method: Compositional matrix adjust. Identities = 67/186 (36%), Positives = 102/186 (54%), Gaps = 13/186 (6%) Query: 535 RPIIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEK 591 RP+++ GP+ K L E FG V HTTR R E DG+DY+FV+ RE M++ Sbjct: 5 RPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFVT-REMMQR 63 Query: 592 DIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIR 651 DI A FIE +++ +LYGTS ++VR V + C+LDV VR ++ L PI IF++ Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQ 123 Query: 652 PRSLENVLEINKRI----TEEQARKAFDRATKLEQEFTE---CFSAIVEGDSFEEIYHKV 704 P SL +VLE R+ TEE K A + + E ++ F ++ D ++ Y + Sbjct: 124 PPSL-DVLEQRLRLRNTETEESLAKRL-AAARTDMESSKEPGLFDLVIINDDLDKAYATL 181 Query: 705 KRVIED 710 K+ + + Sbjct: 182 KQALSE 187 >3LH5-A nrPDB Length = 251 Score = 95.9 bits (237), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 78/295 (26%), Positives = 125/295 (42%), Gaps = 57/295 (19%) Query: 431 FYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA---GDEEWWQARRVHSDSETDDIGF 487 FYIR F+Y+K G LSF G+V V+D G W A R+ + + + G Sbjct: 4 FYIRTHFEYEKESPYG-----LSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERGI 58 Query: 488 IPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRA 547 IP+K R E+ + Q + +YE V E + RP+ I GP D A Sbjct: 59 IPNKNRAEQ-------------LASVQYVQTKFPAYERVVLREAGFLRPVTIFGPIADVA 105 Query: 548 NDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSH 607 + L E PD Y+I + + ++ I+ H Sbjct: 106 REKLAREEPDI--------------YQIAKSEPRDAGTDQRSSGIIRLH----------- 140 Query: 608 LYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRITE 667 +++++ +Q KH +LDV+ NAV RL A +PI +F+ P S + V + R+ Sbjct: 141 -------TIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCP 193 Query: 668 E---QARKAFDRATKLEQEFTECFSAIVEGDSFEE-IYHKVKRVIEDLSGPYIWV 718 E ARK ++R+ KL + F+ + +S + Y +K I+ +WV Sbjct: 194 ESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 248 >3KFV-A nrPDB Length = 308 Score = 87.4 bits (215), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 84/336 (25%), Positives = 132/336 (39%), Gaps = 91/336 (27%) Query: 431 FYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA-----GDEEW----WQARRVHSDSE 481 FYIR F+ + + G L F GDV HV+D G W A R+ D Sbjct: 5 FYIRTHFELEPSPPSG-----LGFTRGDVFHVLDTLHPGPGQSHARGGHWLAVRMGRDLR 59 Query: 482 TDDIGFIPSKRRVE------------------------RREWSRLKAKDWGSSSGSQ-GR 516 + G IP++ R E R E+ RL+ G+ +Q R Sbjct: 60 EQERGIIPNQSRAEQLASLEAAQRAVGVGPGSSAGSNARAEFWRLRGLRRGAKKTTQRSR 119 Query: 517 ED-SVLS-------YETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKF--GSCVPHT 566 ED S L+ YE V E + RP++ILGP D A L +E PD+F V T Sbjct: 120 EDLSALTRQGRYPPYERVVLREASFKRPVVILGPVADIAMQKLTAEMPDQFEIAETVSRT 179 Query: 567 TRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHC 626 P + ++D +VR +AE+ KH Sbjct: 180 DSPSKIIKLD--------------------------------------TVRVIAEKDKHA 201 Query: 627 ILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI---TEEQARKAFDRATKLEQE 683 +LDV+ +A+ RL +PI +F P S + + + + + R+ + +A KL + Sbjct: 202 LLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALRQWLAPASRRSTRRLYAQAQKLRKH 261 Query: 684 FTECFSAIVE-GDSFEEIYHKVKRVIEDLSGPYIWV 718 + F+A + + + Y ++K +I + IW Sbjct: 262 SSHLFTATIPLNGTSDTWYQELKAIIREQQTRPIWT 297 >2QOR-A nrPDB Length = 204 Score = 81.3 bits (199), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 55/189 (29%), Positives = 98/189 (51%), Gaps = 13/189 (6%) Query: 536 PIIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKD 592 P+++ GP+ K +LSEFP +F + TTR KRE E +G DY+FV ++ E+ Sbjct: 14 PLVVCGPSGVGKGTLIKKVLSEFPSRFRFSISCTTRNKREKETNGVDYYFV-DKDDFERK 72 Query: 593 IQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRL-QAAHLHP-IAIFI 650 ++ +F+E +Y ++ YGT +GK C+ +++ N V++L ++ H+ I IF+ Sbjct: 73 LKEGQFLEFDKYANNFYGTLKSEYDLAVGEGKICLFEMNINGVKQLKESKHIQDGIYIFV 132 Query: 651 RPRSLENVLEINKRITEEQARKAFDRATKLEQEFTEC----FSAIVEGDSFEEIYHKVKR 706 +P S++ +L K E+ + R +L +E E F+ + D Y +++ Sbjct: 133 KPPSIDILLGRLKNRNTEKPEEINKRMQELTREMDEADKVGFNYFIVNDDLARTYAELR- 191 Query: 707 VIEDLSGPY 715 E L G Y Sbjct: 192 --EYLLGSY 198 >6MFU-A nrPDB Length = 225 Score = 78.6 bits (192), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 52/155 (33%), Positives = 79/155 (50%), Gaps = 15/155 (9%) Query: 535 RPIIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEK 591 RP++I GP+ K L P+ FG V HTTR R E +GR+YHFV+ E ME Sbjct: 20 RPLVICGPSGTGKSTLLKTLFESQPNTFGFSVSHTTRKPRPGEENGREYHFVTKEEFME- 78 Query: 592 DIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAH------LHP 645 + +F+E ++ + YGT+ ++ A + CILD+ V +L+A L P Sbjct: 79 GVGKGEFLEWAEFGGNCYGTTFAAL--TALHPRRCILDIELQGVLQLKAKAPLQTPPLEP 136 Query: 646 IAIFIRPRSLENVL-EINKRITEEQA--RKAFDRA 677 + +F+ P S+ + ++ R TE A RK D A Sbjct: 137 VFLFLSPPSISQLKSRLSGRGTETDASIRKRLDAA 171 >1Z6G-A nrPDB Length = 218 Score = 76.3 bits (186), Expect = 5e-14, Method: Composition-based stats. Identities = 56/180 (31%), Positives = 92/180 (51%), Gaps = 12/180 (6%) Query: 536 PIIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKD 592 P++I GP+ K LL+EFP+ F V TTR KRE E +G DY+F+ + E Sbjct: 25 PLVICGPSGVGKGTLIKKLLNEFPNYFYFSVSCTTRKKREKEKEGVDYYFI-DKTIFEDK 83 Query: 593 IQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRL-QAAHL-HPIAIFI 650 ++ F+E Y ++ YGT + EQ K C+ +++ N V++L ++ H+ + + IFI Sbjct: 84 LKNEDFLEYDNYANNFYGTLKSEYDKAKEQNKICLFEMNINGVKQLKKSTHIKNALYIFI 143 Query: 651 RPRSLENVL-EINKRITEEQARKAFDRATKLEQEFTEC----FSAIVEGDSFEEIYHKVK 705 +P S + +L + R TE Q + R +L E E F+ + D Y ++K Sbjct: 144 KPPSTDVLLSRLLTRNTENQ-EQIQKRMEQLNIELHEANLLNFNLSIINDDLTLTYQQLK 202 >2QT5-A nrPDB Length = 200 Score = 68.9 bits (167), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 55/228 (24%), Positives = 93/228 (40%), Gaps = 60/228 (26%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG +++GG+ P V+ + +GG A + +L +GD I AVN + L H++ + Sbjct: 21 LGLTVSGGIDKDGKP-----RVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDEII 75 Query: 230 AALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPT 289 + LKN + V L+V Y P ++ S + + Sbjct: 76 SLLKNVGERVVLEV----------EYELPPVSIQGSSVMFRTV----------------- 108 Query: 290 SPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGG-----EDGEGIFISFILAG 344 + +H+ GF I GG + I+ + G Sbjct: 109 -----------------------EVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITCVRPG 145 Query: 345 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQY 392 GPAD G ++ GD++LSV+G+ L +H +A LK GQ T++ +Y Sbjct: 146 GPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEY 193 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 49/178 (27%), Positives = 85/178 (47%), Gaps = 20/178 (11%) Query: 68 LERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 +++ + LG +++GG D D ++ + GG AA+ +L V D I VN +++ + Sbjct: 14 MKKEGTTLGLTVSGGIDK-----DGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAK 68 Query: 128 VTHSAAVEALKEAGSIVRLYVMRRKPPAE--------KVMEIKLIKGPKGLGFSIAGGVG 179 H + LK G V L V PP + +E+ L K GF I GG Sbjct: 69 FRHDEIISLLKNVGERVVLEVEYELPPVSIQGSSVMFRTVEVTLHKEGNTFGFVIRGGAH 128 Query: 180 ---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKN 234 N+ P + +T + GG A ++G ++ GD++L+V+ + L H +A++ LK Sbjct: 129 DDRNKSRP----VVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQ 182 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 50/102 (49%), Gaps = 4/102 (3%) Query: 50 YEL---QVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAA 106 YEL + G+ E+TL + + GF I GG + P + IT + PGG A Sbjct: 91 YELPPVSIQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRP-VVITCVRPGGPAD 149 Query: 107 QDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYV 148 ++G ++ D +L V+ + + TH+ A+ LK+ G L + Sbjct: 150 REGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLI 191 Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 27/80 (33%), Positives = 44/80 (55%), Gaps = 1/80 (1%) Query: 315 VIHRGSTGLGFNIVGGEDGEGI-FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 ++ + T LG + GG D +G +S + GG A S +L GD I +VNG++L H+ Sbjct: 13 LMKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHD 72 Query: 374 QAAIALKNAGQTVTIIAQYK 393 + LKN G+ V + +Y+ Sbjct: 73 EIISLLKNVGERVVLEVEYE 92 >2J41-A nrPDB Length = 207 Score = 65.5 bits (158), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 49/179 (27%), Positives = 89/179 (49%), Gaps = 8/179 (4%) Query: 537 IIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI 593 I++ GP+ K + + + + TTR RE E+DG DY F +R+ E I Sbjct: 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFF-KTRDAFEALI 67 Query: 594 QAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPR 653 + +FIE +Y + YGT VQ V++ ++G L++ ++++ + IF+ P Sbjct: 68 KDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPP 127 Query: 654 SLENVLE-INKRITE--EQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 709 SLE++ E + R TE E+ + + A K E E + +V D E ++++ ++E Sbjct: 128 SLEHLRERLVGRGTESDEKIQSRINEARK-EVEMMNLYDYVVVNDEVELAKNRIQCIVE 185 >5ZDS-A nrPDB Length = 96 Score = 63.9 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 39/95 (41%), Positives = 56/95 (58%), Gaps = 8/95 (8%) Query: 59 GEMEYEEITLERGNSGLGFSIAGG--TDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDS 116 GE+ + E+ E G LGFS+ GG T PH G I++ IIPGG AA++G++ D Sbjct: 7 GEIYFVELVKEDGT--LGFSVTGGINTSVPHGG----IYVKSIIPGGPAAKEGQILQGDR 60 Query: 117 ILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 +L V+ V + +TH AV+ LK G + RL + RR Sbjct: 61 LLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERR 95 Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 33/81 (40%), Positives = 47/81 (58%), Gaps = 2/81 (2%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 ++L+K LGFS+ GG+ N +P IYV II GG A K+G++ GD++L V+ V L Sbjct: 12 VELVKEDGTLGFSVTGGI-NTSVP-HGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSL 69 Query: 221 EDVMHEDAVAALKNTYDVVYL 241 + H+ AV LK V L Sbjct: 70 CGLTHKQAVQCLKGPGQVARL 90 Score = 55.1 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 27/75 (36%), Positives = 45/75 (60%), Gaps = 4/75 (5%) Query: 323 LGFNIVGGEDGE----GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIA 378 LGF++ GG + GI++ I+ GGPA G++ +GD++L V+GV L +H+QA Sbjct: 21 LGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSLCGLTHKQAVQC 80 Query: 379 LKNAGQTVTIIAQYK 393 LK GQ ++ + + Sbjct: 81 LKGPGQVARLVLERR 95 >4OEP-A nrPDB Length = 107 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 34/93 (36%), Positives = 55/93 (59%), Gaps = 4/93 (4%) Query: 62 EYEEITLERG-NSGLGFSIAGGTDNPHI-GDDPSIFITKIIPGGAAAQDGRLRVNDSILF 119 E +TL R G G +I+GG DNPH + SI I+ ++ GG A +G+L+ ND + Sbjct: 7 EQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPA--EGQLQENDRVAM 64 Query: 120 VNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK 152 VN V + V H+ AV+ L+++G ++ + R+K Sbjct: 65 VNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKK 97 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/92 (35%), Positives = 47/92 (51%), Gaps = 10/92 (10%) Query: 310 EPRRIVIHRG-STGLGFNIVGGED------GE-GIFISFILAGGPADLSGELRKGDQILS 361 E + +HR G G I GG D GE I IS +L GGPA+ G+L++ D++ Sbjct: 7 EQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAM 64 Query: 362 VNGVDLRNASHEQAAIALKNAGQTVTIIAQYK 393 VNGV + N H A L+ +G+ I + K Sbjct: 65 VNGVSMDNVEHAFAVQQLRKSGKNAKITIRRK 96 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 25/68 (36%), Positives = 42/68 (61%), Gaps = 3/68 (4%) Query: 169 GLGFSIAGGVGNQHI-PGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHED 227 G G +I+GG N H G+ SI ++ +++GG A +G+LQ D++ VN V +++V H Sbjct: 20 GFGIAISGGRDNPHFQSGETSIVISDVLKGGPA--EGQLQENDRVAMVNGVSMDNVEHAF 77 Query: 228 AVAALKNT 235 AV L+ + Sbjct: 78 AVQQLRKS 85 >1WFV-A nrPDB Length = 103 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 32/97 (32%), Positives = 56/97 (57%), Gaps = 6/97 (6%) Query: 55 NGTEGE-MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRV 113 +G+ G+ +Y + +E+G G GFSI GG + +++ ++ G A ++GR+RV Sbjct: 3 SGSSGQDFDYFTVDMEKGAKGFGFSIRGGREYKM-----DLYVLRLAEDGPAIRNGRMRV 57 Query: 114 NDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 D I+ +N R++TH+ A+E +K G VRL + R Sbjct: 58 GDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKR 94 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 27/89 (30%), Positives = 49/89 (55%), Gaps = 5/89 (5%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 + + KG KG GFSI GG + +YV ++ E G A ++GR+++GD+I+ +N Sbjct: 15 VDMEKGAKGFGFSIRGGREYKM-----DLYVLRLAEDGPAIRNGRMRVGDQIIEINGEST 69 Query: 221 EDVMHEDAVAALKNTYDVVYLKVAKPSNA 249 D+ H A+ +K+ V L + + + + Sbjct: 70 RDMTHARAIELIKSGGRRVRLLLKRGTGS 98 Score = 46.2 bits (108), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 24/77 (31%), Positives = 47/77 (61%), Gaps = 1/77 (1%) Query: 316 IHRGSTGLGFNIVGGEDGE-GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + +G+ G GF+I GG + + +++ + GPA +G +R GDQI+ +NG R+ +H + Sbjct: 17 MEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMTHAR 76 Query: 375 AAIALKNAGQTVTIIAQ 391 A +K+ G+ V ++ + Sbjct: 77 AIELIKSGGRRVRLLLK 93 >1P1D-A nrPDB Length = 196 Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 48/180 (26%), Positives = 88/180 (48%), Gaps = 11/180 (6%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 +G G + G P + I+ I A + G L++ D ++ +N + + T Sbjct: 18 TGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEE 76 Query: 133 AVEALKEAGSIVRLYVMRRKPPAEKVMEIK---LIKGPKG----LGFSIAGGVGNQHIPG 185 A + L+++ ++ + AE V+ +K PK LG +I+ + PG Sbjct: 77 ANQLLRDSSITSKVTLEIEFDVAESVIPSSGTFHVKLPKKHSVELGITISSPSSRK--PG 134 Query: 186 DNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 D + ++ I +G AH+ G L++GDK+LA++++ L+ EDAV L+ D+V LK+ K Sbjct: 135 D-PLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDSCSMEDAVQILQQCEDLVKLKIRK 193 Score = 37.0 bits (84), Expect = 0.027, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 32/49 (65%) Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQT 385 IS+I A PA+ G L+ GD+++++NG+ +++ E+A L+++ T Sbjct: 39 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSIT 87 >2R4H-A nrPDB Length = 112 Score = 59.3 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 32/99 (32%), Positives = 54/99 (54%), Gaps = 9/99 (9%) Query: 56 GTEG----EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRL 111 GTE M++ + LERG G GFS+ GG + + +++ ++ G A + G++ Sbjct: 14 GTENLYFQSMDFYTVELERGAKGFGFSLRGGREY-----NMDLYVLRLAEDGPAERSGKM 68 Query: 112 RVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 R+ D IL +N + + HS A+E +K G VRL++ R Sbjct: 69 RIGDEILEINGETTKNMKHSRAIELIKNGGRRVRLFLKR 107 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 27/76 (35%), Positives = 46/76 (60%), Gaps = 1/76 (1%) Query: 314 IVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 + + RG+ G GF++ GG E +++ + GPA+ SG++R GD+IL +NG +N H Sbjct: 28 VELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERSGKMRIGDEILEINGETTKNMKH 87 Query: 373 EQAAIALKNAGQTVTI 388 +A +KN G+ V + Sbjct: 88 SRAIELIKNGGRRVRL 103 Score = 49.7 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 25/74 (33%), Positives = 44/74 (59%), Gaps = 5/74 (6%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 ++L +G KG GFS+ GG + +YV ++ E G A + G+++IGD+IL +N Sbjct: 28 VELERGAKGFGFSLRGGR-----EYNMDLYVLRLAEDGPAERSGKMRIGDEILEINGETT 82 Query: 221 EDVMHEDAVAALKN 234 +++ H A+ +KN Sbjct: 83 KNMKHSRAIELIKN 96 >3TSV-A nrPDB Length = 124 Score = 57.8 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 38/95 (40%), Positives = 52/95 (54%), Gaps = 4/95 (4%) Query: 307 IPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVD 366 I R ++V R +G + GG D GIF++ +L PA G L +GDQIL VN VD Sbjct: 25 ILRPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVD 82 Query: 367 LRNASHEQAAIALKN--AGQTVTIIAQYKPEEYSR 399 N E+A + L + G+ VTI+AQ K + Y R Sbjct: 83 FTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRR 117 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 10/74 (13%) Query: 161 IKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+V Sbjct: 30 MKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNV 81 Query: 219 GLEDVMHEDAVAAL 232 +++ E+AV L Sbjct: 82 DFTNIIREEAVLFL 95 Score = 32.7 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +G+S +G +AGG +D IF+ ++ AA++G L D IL VN VD Sbjct: 33 VKFRKGDS-VGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDF 83 Query: 126 REVTHSAAVEALKE--AGSIVRLYVMRRKPPAEKVME 160 + AV L + G V + ++K +++E Sbjct: 84 TNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVE 120 >3TAU-A nrPDB Length = 208 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 50/198 (25%), Positives = 82/198 (41%), Gaps = 24/198 (12%) Query: 537 IIILGPT---KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI 593 I++ GP+ K + + + F + TTR RE E DG DY+F SRE E+ I Sbjct: 11 IVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYF-RSREVFEQAI 69 Query: 594 QAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPR 653 + K +E +Y + YGT ++ V E G L++ +++ A I IF+ P Sbjct: 70 KDGKMLEYAEYVGNYYGTPLEYVEEKLAAGVDIFLEIEVQGAMQVRKAMPEGIFIFLTPP 129 Query: 654 SL------------------ENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGD 695 L E +E K+ E A + + + IVE + Sbjct: 130 DLSELKNRIIGRGTESMEVVEERMETAKKEIEMMASYDYAVVNDVVANAVQKIKGIVETE 189 Query: 696 SF--EEIYHKVKRVIEDL 711 E + H+ K+++E L Sbjct: 190 HLKTERVIHRYKKMLEGL 207 >3SHU-A nrPDB Length = 95 Score = 55.8 bits (133), Expect = 7e-08, Method: Composition-based stats. Identities = 36/89 (40%), Positives = 50/89 (56%), Gaps = 4/89 (4%) Query: 313 RIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 ++V R +G + GG D GIF++ +L PA G L +GDQIL VN VD N Sbjct: 6 KLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNIIR 63 Query: 373 EQAAIALKN--AGQTVTIIAQYKPEEYSR 399 E+A + L + G+ VTI+AQ K + Y R Sbjct: 64 EEAVLFLLDLPKGEEVTILAQKKKDVYRR 92 Score = 40.0 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 10/74 (13%) Query: 161 IKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+V Sbjct: 5 MKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNV 56 Query: 219 GLEDVMHEDAVAAL 232 +++ E+AV L Sbjct: 57 DFTNIIREEAVLFL 70 Score = 32.3 bits (72), Expect = 0.68, Method: Composition-based stats. Identities = 27/97 (27%), Positives = 46/97 (47%), Gaps = 11/97 (11%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +G+S +G +AGG +D IF+ ++ AA++G L D IL VN VD Sbjct: 8 VKFRKGDS-VGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDF 58 Query: 126 REVTHSAAVEALKE--AGSIVRLYVMRRKPPAEKVME 160 + AV L + G V + ++K +++E Sbjct: 59 TNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRRIVE 95 >1UEQ-A nrPDB Length = 123 Score = 55.5 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 37/103 (35%), Positives = 54/103 (52%), Gaps = 12/103 (11%) Query: 53 QVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLR 112 Q+ GT + TL++ N G GF+I GG D P D + + +IP G AAQDG++ Sbjct: 15 QLKGT-----FLSTTLKKSNMGFGFTIIGG-DEP----DEFLQVKSVIPDGPAAQDGKME 64 Query: 113 VNDSILFVNEVDVREVTHSAAVEALKEA--GSIVRLYVMRRKP 153 D I+++NEV V TH+ V+ + G V L + R P Sbjct: 65 TGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYP 107 Score = 37.0 bits (84), Expect = 0.033, Method: Composition-based stats. Identities = 23/76 (30%), Positives = 36/76 (47%), Gaps = 5/76 (6%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 + L K G GF+I GG D + V +I G A +DG+++ GD I+ +N V Sbjct: 21 LSTTLKKSNMGFGFTIIGG-----DEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEV 75 Query: 219 GLEDVMHEDAVAALKN 234 + H D V ++ Sbjct: 76 CVLGHTHADVVKLFQS 91 Score = 36.6 bits (83), Expect = 0.035, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 40/77 (51%), Gaps = 3/77 (3%) Query: 316 IHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + + + G GF I+GG E E + + ++ GPA G++ GD I+ +N V + +H Sbjct: 25 LKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHAD 84 Query: 375 AAIALKNA--GQTVTII 389 ++ GQ+V ++ Sbjct: 85 VVKLFQSVPIGQSVNLV 101 >1UEZ-A nrPDB Length = 101 Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 33/90 (36%), Positives = 54/90 (60%), Gaps = 6/90 (6%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 +G+ GE+ + + + GLGFSI GG+++ I+++ + PG A ++G LRV Sbjct: 3 SGSSGEVRLVSLRRAKAHEGLGFSIRGGSEH-----GVGIYVSLVEPGSLAEKEG-LRVG 56 Query: 115 DSILFVNEVDVREVTHSAAVEALKEAGSIV 144 D IL VN+ + VTH+ AV+ALK + +V Sbjct: 57 DQILRVNDKSLARVTHAEAVKALKGSKKLV 86 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/83 (40%), Positives = 51/83 (61%), Gaps = 6/83 (7%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +++ ++ K +GLGFSI GG ++H G IYV+ + G A K+G L++GD+IL VN Sbjct: 10 RLVSLRRAKAHEGLGFSIRGG--SEHGVG---IYVSLVEPGSLAEKEG-LRVGDQILRVN 63 Query: 217 SVGLEDVMHEDAVAALKNTYDVV 239 L V H +AV ALK + +V Sbjct: 64 DKSLARVTHAEAVKALKGSKKLV 86 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 31/66 (46%), Positives = 40/66 (60%), Gaps = 2/66 (3%) Query: 322 GLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALK 380 GLGF+I GG E G GI++S + G A+ G LR GDQIL VN L +H +A ALK Sbjct: 22 GLGFSIRGGSEHGVGIYVSLVEPGSLAEKEG-LRVGDQILRVNDKSLARVTHAEAVKALK 80 Query: 381 NAGQTV 386 + + V Sbjct: 81 GSKKLV 86 >3EGH-C nrPDB Length = 170 Score = 54.7 bits (130), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 32/100 (32%), Positives = 52/100 (52%), Gaps = 1/100 (1%) Query: 147 YVMRRKPPAEKVMEIKLIKGPKGLGFSIAG-GVGNQHIPGDNSIYVTKIIEGGAAHKDGR 205 Y + ++ ++ ++L K +GLG SI G G G I+V + EGGAAH+DGR Sbjct: 70 YELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGR 129 Query: 206 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 +Q+ D ++ V+ L V A + L+NT V + + Sbjct: 130 IQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGR 169 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 31/91 (34%), Positives = 48/91 (52%), Gaps = 1/91 (1%) Query: 61 MEYEEITLERGNSGLGFSIAGGTDNPHIG-DDPSIFITKIIPGGAAAQDGRLRVNDSILF 119 +E + LE+ + GLG SI G +G + IF+ + GGAA +DGR++VND ++ Sbjct: 79 LELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVE 138 Query: 120 VNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 V+ + VT S A L+ VR + R Sbjct: 139 VDGTSLVGVTQSFAASVLRNTKGRVRFMIGR 169 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 22/75 (29%), Positives = 37/75 (49%), Gaps = 7/75 (9%) Query: 314 IVIHRGSTGLGFNIVG-------GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVD 366 + + + S GLG +I+G G + GIF+ + GG A G ++ D ++ V+G Sbjct: 84 VELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTS 143 Query: 367 LRNASHEQAAIALKN 381 L + AA L+N Sbjct: 144 LVGVTQSFAASVLRN 158 >3FY5-A nrPDB Length = 91 Score = 54.3 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 3/65 (4%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV Sbjct: 13 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAV 69 Query: 230 AALKN 234 L++ Sbjct: 70 RVLRD 74 Score = 42.7 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 75 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 134 LG SI G ++ D I+I I+ GGA A DGR+ D +L VN+++ +++ AV Sbjct: 13 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAV 69 Query: 135 EALKE 139 L++ Sbjct: 70 RVLRD 74 Score = 41.2 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 323 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L Sbjct: 13 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVL 72 Query: 380 KN 381 ++ Sbjct: 73 RD 74 >4Q2Q-A nrPDB Length = 102 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 35/87 (40%), Positives = 48/87 (55%), Gaps = 4/87 (4%) Query: 309 REPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 R ++V R +G + GG D GIF++ +L PA G L +GDQIL VN VD Sbjct: 5 RPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFT 62 Query: 369 NASHEQAAIALKN--AGQTVTIIAQYK 393 N E+A + L + G+ VTI+AQ K Sbjct: 63 NIIREEAVLFLLDLPKGEEVTILAQKK 89 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 28/74 (37%), Positives = 43/74 (58%), Gaps = 10/74 (13%) Query: 161 IKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+V Sbjct: 8 MKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNV 59 Query: 219 GLEDVMHEDAVAAL 232 +++ E+AV L Sbjct: 60 DFTNIIREEAVLFL 73 Score = 32.3 bits (72), Expect = 0.83, Method: Composition-based stats. Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 9/69 (13%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +G+S +G +AGG +D IF+ ++ AA++G L D IL VN VD Sbjct: 11 VKFRKGDS-VGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDF 61 Query: 126 REVTHSAAV 134 + AV Sbjct: 62 TNIIREEAV 70 >2JIL-A nrPDB Length = 97 Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 5/90 (5%) Query: 314 IVIHRGSTGLGFNIVGG-----EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 + +H+ GF I GG + I+ + GGPAD G ++ GD++LSV+G+ L Sbjct: 7 VTLHKEGNTFGFVIRGGAHDDRNKSRPVVITSVRPGGPADREGTIKPGDRLLSVDGIRLL 66 Query: 369 NASHEQAAIALKNAGQTVTIIAQYKPEEYS 398 +H +A LK GQ ++ +Y E + Sbjct: 67 GTTHAEAMSILKQCGQEAALLIEYDVSETA 96 Score = 46.2 bits (108), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 27/88 (30%), Positives = 45/88 (51%), Gaps = 1/88 (1%) Query: 61 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 M E+TL + + GF I GG + P + IT + PGG A ++G ++ D +L V Sbjct: 2 MRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRP-VVITSVRPGGPADREGTIKPGDRLLSV 60 Query: 121 NEVDVREVTHSAAVEALKEAGSIVRLYV 148 + + + TH+ A+ LK+ G L + Sbjct: 61 DGIRLLGTTHAEAMSILKQCGQEAALLI 88 Score = 38.5 bits (88), Expect = 0.012, Method: Compositional matrix adjust. Identities = 24/81 (29%), Positives = 43/81 (53%), Gaps = 7/81 (8%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKIL 213 + +E+ L K GF I GG N+ P + +T + GG A ++G ++ GD++L Sbjct: 3 RTVEVTLHKEGNTFGFVIRGGAHDDRNKSRP----VVITSVRPGGPADREGTIKPGDRLL 58 Query: 214 AVNSVGLEDVMHEDAVAALKN 234 +V+ + L H +A++ LK Sbjct: 59 SVDGIRLLGTTHAEAMSILKQ 79 >2DC2-A nrPDB Length = 103 Score = 53.9 bits (128), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 41/102 (40%), Positives = 52/102 (50%), Gaps = 24/102 (23%) Query: 295 SPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGEL 353 P+ K LL +ED GLG +I GG E G I IS I G PAD G L Sbjct: 8 GPIRKVLLLKED-------------HEGLGISITGGKEHGVPILISEIHPGQPADRCGGL 54 Query: 354 RKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPE 395 GD IL+VNGV+LR+ H++A VTI++Q + E Sbjct: 55 HVGDAILAVNGVNLRDTKHKEA----------VTILSQQRGE 86 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/96 (37%), Positives = 53/96 (55%), Gaps = 14/96 (14%) Query: 154 PAEKVMEIKLIKGPKGLGFSIAGGVGNQH-IPGDNSIYVTKIIEGGAAHKDGRLQIGDKI 212 P KV+ +K + +GLG SI GG +H +P I +++I G A + G L +GD I Sbjct: 9 PIRKVLLLK--EDHEGLGISITGG--KEHGVP----ILISEIHPGQPADRCGGLHVGDAI 60 Query: 213 LAVNSVGLEDVMHEDAVAALKNT-----YDVVYLKV 243 LAVN V L D H++AV L ++VVY+ + Sbjct: 61 LAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYVAL 96 Score = 45.4 bits (106), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 5/74 (6%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + L+ + GLG SI GG ++ I I++I PG A + G L V D+IL VN V++ Sbjct: 14 LLLKEDHEGLGISITGGKEH-----GVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 68 Query: 126 REVTHSAAVEALKE 139 R+ H AV L + Sbjct: 69 RDTKHKEAVTILSQ 82 >3CBX-A nrPDB Length = 105 Score = 53.5 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 33/87 (37%), Positives = 49/87 (56%), Gaps = 12/87 (13%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV Sbjct: 19 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 75 Query: 230 AALKNTYDVVY------LKVAKPSNAY 250 L+ D+V+ L VAK + Sbjct: 76 RVLR---DIVHKPGPIVLTVAKSGGGW 99 Score = 42.4 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 23/65 (35%), Positives = 37/65 (56%), Gaps = 3/65 (4%) Query: 75 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 134 LG SI G ++ D I+I I+ GGA A DGR+ D +L VN+++ +++ AV Sbjct: 19 LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 75 Query: 135 EALKE 139 L++ Sbjct: 76 RVLRD 80 Score = 40.8 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 323 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L Sbjct: 19 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 78 Query: 380 KN 381 ++ Sbjct: 79 RD 80 >4JOF-A nrPDB Length = 87 Score = 53.5 bits (127), Expect = 3e-07, Method: Compositional matrix adjust. Identities = 41/102 (40%), Positives = 52/102 (50%), Gaps = 24/102 (23%) Query: 295 SPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGEL 353 P+ K LL +ED GLG +I GG E G I IS I G PAD G L Sbjct: 1 GPIRKVLLLKED-------------HEGLGISITGGKEHGVPILISEIHPGQPADRCGGL 47 Query: 354 RKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPE 395 GD IL+VNGV+LR+ H++A VTI++Q + E Sbjct: 48 HVGDAILAVNGVNLRDTKHKEA----------VTILSQQRGE 79 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 36/94 (38%), Positives = 52/94 (55%), Gaps = 14/94 (14%) Query: 154 PAEKVMEIKLIKGPKGLGFSIAGGVGNQH-IPGDNSIYVTKIIEGGAAHKDGRLQIGDKI 212 P KV+ +K + +GLG SI GG +H +P I +++I G A + G L +GD I Sbjct: 2 PIRKVLLLK--EDHEGLGISITGG--KEHGVP----ILISEIHPGQPADRCGGLHVGDAI 53 Query: 213 LAVNSVGLEDVMHEDAVAALKNT-----YDVVYL 241 LAVN V L D H++AV L ++VVY+ Sbjct: 54 LAVNGVNLRDTKHKEAVTILSQQRGEIEFEVVYV 87 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 5/74 (6%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + L+ + GLG SI GG ++ I I++I PG A + G L V D+IL VN V++ Sbjct: 7 LLLKEDHEGLGISITGGKEH-----GVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 61 Query: 126 REVTHSAAVEALKE 139 R+ H AV L + Sbjct: 62 RDTKHKEAVTILSQ 75 >2MX6-A nrPDB Length = 90 Score = 53.1 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 28/64 (43%), Positives = 40/64 (62%), Gaps = 3/64 (4%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG SI VG + GD IY+ I++GGA DGR++ GD +L VN V E++ ++DAV Sbjct: 15 LGISI---VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAV 71 Query: 230 AALK 233 L+ Sbjct: 72 RVLR 75 Score = 44.7 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 25/65 (38%), Positives = 38/65 (58%), Gaps = 3/65 (4%) Query: 75 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 134 LG SI G +++ D I+I I+ GGA A DGR+ D +L VN+V+ +++ AV Sbjct: 15 LGISIVGQSNDR---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAV 71 Query: 135 EALKE 139 L+E Sbjct: 72 RVLRE 76 Score = 40.0 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 9/75 (12%) Query: 323 LGFNIVGGEDGEG---IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 LG +IVG + G I+I I+ GG G + GD +L VN V+ N S++ A L Sbjct: 15 LGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVL 74 Query: 380 KNAGQTVTIIAQYKP 394 + I++Q P Sbjct: 75 RE------IVSQTGP 83 >2LOB-A nrPDB Length = 112 Score = 53.1 bits (126), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 35/75 (46%), Positives = 44/75 (58%), Gaps = 11/75 (14%) Query: 322 GLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALK 380 GLG +I GG E G I IS I G PAD G L GD IL+VNGV+LR+ H++A Sbjct: 40 GLGISITGGKEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHKEA----- 94 Query: 381 NAGQTVTIIAQYKPE 395 VTI++Q + E Sbjct: 95 -----VTILSQQRGE 104 Score = 45.4 bits (106), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 28/74 (37%), Positives = 41/74 (55%), Gaps = 5/74 (6%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + L+ + GLG SI GG ++ I I++I PG A + G L V D+IL VN V++ Sbjct: 32 LLLKEDHEGLGISITGGKEH-----GVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 86 Query: 126 REVTHSAAVEALKE 139 R+ H AV L + Sbjct: 87 RDTKHKEAVTILSQ 100 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 32/80 (40%), Positives = 45/80 (56%), Gaps = 12/80 (15%) Query: 168 KGLGFSIAGGVGNQH-IPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHE 226 +GLG SI GG +H +P I +++I G A + G L +GD ILAVN V L D H+ Sbjct: 39 EGLGISITGG--KEHGVP----ILISEIHPGQPADRCGGLHVGDAILAVNGVNLRDTKHK 92 Query: 227 DAVAALKNT-----YDVVYL 241 +AV L ++VVY+ Sbjct: 93 EAVTILSQQRGEIEFEVVYV 112 >3SUZ-A nrPDB Length = 388 Score = 52.8 bits (125), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 42/157 (26%), Positives = 75/157 (47%), Gaps = 25/157 (15%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNE---VDVREVTHSAAVEALKEAGSIVRLYV 148 P++ + ++ GG AA+ G+L + D I+ +N V + T ++ LK V+L + Sbjct: 232 PTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNI 290 Query: 149 MRRKPPAEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGR 205 + PP V LIK P LGFS+ G+ + ++ GG A + G Sbjct: 291 V-SCPPVTTV----LIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG- 332 Query: 206 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLK 242 +++G +I+ +N + HE V AL N+ +++K Sbjct: 333 VRVGHRIIEINGQSVVATAHEKIVQALSNSVGEIHMK 369 Score = 37.7 bits (86), Expect = 0.016, Method: Compositional matrix adjust. Identities = 36/103 (34%), Positives = 50/103 (48%), Gaps = 13/103 (12%) Query: 317 HRGSTGLGFNIVGGEDGEG-----IFISFILAGGPADLSGELRKGDQILSVNG---VDLR 368 H+G LG +V E G G + ++ ++ GGPA SG+L GDQI+S+NG V L Sbjct: 213 HKGEI-LGVVVV--ESGWGSILPTVILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLP 269 Query: 369 NASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQL 411 A+ + LKN Q I P + K DL+ QL Sbjct: 270 LATCQGIIKGLKNQTQVKLNIVSCPP--VTTVLIKRPDLKYQL 310 Score = 30.0 bits (66), Expect = 3.5, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 7/60 (11%) Query: 323 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 382 LGF++ G I ++ GG A+ G +R G +I+ +NG + +HE+ AL N+ Sbjct: 310 LGFSVQNG------IICSLMRGGIAERGG-VRVGHRIIEINGQSVVATAHEKIVQALSNS 362 >2Q9V-A nrPDB Length = 90 Score = 52.0 bits (123), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 29/72 (40%), Positives = 42/72 (58%), Gaps = 1/72 (1%) Query: 314 IVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 I + R TG GF I+GG E GE I+I I+ G AD G LR GD+++SV+G + SH Sbjct: 6 IFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELISVDGTPVIGKSH 65 Query: 373 EQAAIALKNAGQ 384 + ++ A + Sbjct: 66 QLVVQLMQQAAK 77 Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 28/77 (36%), Positives = 43/77 (55%), Gaps = 5/77 (6%) Query: 64 EEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEV 123 ++I L R +G GF I GG + +P I+I I+P GAA DGRLR D ++ V+ Sbjct: 4 QDIFLWRKETGFGFRILGGNEP----GEP-IYIGHIVPLGAADTDGRLRSGDELISVDGT 58 Query: 124 DVREVTHSAAVEALKEA 140 V +H V+ +++A Sbjct: 59 PVIGKSHQLVVQLMQQA 75 Score = 37.4 bits (85), Expect = 0.025, Method: Compositional matrix adjust. Identities = 25/75 (33%), Positives = 41/75 (54%), Gaps = 5/75 (6%) Query: 160 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG 219 +I L + G GF I GG + PG+ IY+ I+ GAA DGRL+ GD++++V+ Sbjct: 5 DIFLWRKETGFGFRILGG----NEPGE-PIYIGHIVPLGAADTDGRLRSGDELISVDGTP 59 Query: 220 LEDVMHEDAVAALKN 234 + H+ V ++ Sbjct: 60 VIGKSHQLVVQLMQQ 74 >1MFG-A nrPDB Length = 95 Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 34/90 (37%), Positives = 51/90 (56%), Gaps = 6/90 (6%) Query: 159 MEIKLIKGPKGLGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 + +++ K P+ LGFSI+GGVG N P D+ I+VT++ G A K LQ GDKI+ Sbjct: 5 IRVRVEKDPE-LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQA 61 Query: 216 NSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 N ++ H AV+ LK + V L + + Sbjct: 62 NGYSFINIEHGQAVSLLKTFQNTVELIIVR 91 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 5/79 (6%) Query: 75 LGFSIAGGTD---NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHS 131 LGFSI+GG NP DD IF+T++ P G A++ L+ D I+ N + H Sbjct: 15 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHG 72 Query: 132 AAVEALKEAGSIVRLYVMR 150 AV LK + V L ++R Sbjct: 73 QAVSLLKTFQNTVELIIVR 91 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 323 LGFNIVGG---------EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 LGF+I GG D +GIF++ + GPA S L+ GD+I+ NG N H Sbjct: 15 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPA--SKLLQPGDKIIQANGYSFINIEHG 72 Query: 374 QAAIALKNAGQTVTII 389 QA LK TV +I Sbjct: 73 QAVSLLKTFQNTVELI 88 >5ZYS-A nrPDB Length = 97 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 28/70 (40%), Positives = 40/70 (57%), Gaps = 1/70 (1%) Query: 314 IVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 I + R TG GF I+GG E GE I+I I+ G AD G LR GD+++ V+G + SH Sbjct: 13 IFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVIGKSH 72 Query: 373 EQAAIALKNA 382 + ++ A Sbjct: 73 QLVVQLMQQA 82 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 45/85 (52%), Gaps = 5/85 (5%) Query: 56 GTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVND 115 G+ + + ++I L R +G GF I GG + I+I I+P GAA DGRLR D Sbjct: 3 GSIPDYQEQDIFLWRKETGFGFRILGGNE-----PGEPIYIGHIVPLGAADTDGRLRSGD 57 Query: 116 SILFVNEVDVREVTHSAAVEALKEA 140 ++ V+ V +H V+ +++A Sbjct: 58 ELICVDGTPVIGKSHQLVVQLMQQA 82 Score = 37.4 bits (85), Expect = 0.024, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 42/82 (51%), Gaps = 5/82 (6%) Query: 154 PAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKIL 213 P + +I L + G GF I GG + PG+ IY+ I+ GAA DGRL+ GD+++ Sbjct: 6 PDYQEQDIFLWRKETGFGFRILGG----NEPGE-PIYIGHIVPLGAADTDGRLRSGDELI 60 Query: 214 AVNSVGLEDVMHEDAVAALKNT 235 V+ + H+ V ++ Sbjct: 61 CVDGTPVIGKSHQLVVQLMQQA 82 >1U3B-A nrPDB Length = 185 Score = 50.4 bits (119), Expect = 3e-06, Method: Composition-based stats. Identities = 44/165 (26%), Positives = 78/165 (47%), Gaps = 26/165 (15%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNE---VDVREVTHSAAVEALKEAGSIVRLYV 148 P++ I ++ GG A + G+L + D I+ +N V + T + ++ LK S V+L + Sbjct: 29 PTVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQ-SRVKLNI 87 Query: 149 MRRKPPAEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGR 205 + R PP V LI+ P LGFS+ G+ + ++ GG A + G Sbjct: 88 V-RCPPVTTV----LIRRPDLRYQLGFSVQNGI------------ICSLMRGGIAERGG- 129 Query: 206 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAY 250 +++G +I+ +N + HE V L N +++K P+ Y Sbjct: 130 VRVGHRIIEINGQSVVATPHEKIVHILSNAVGEIHMKTM-PAAMY 173 Score = 38.9 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 16/32 (50%), Positives = 24/32 (75%) Query: 336 IFISFILAGGPADLSGELRKGDQILSVNGVDL 367 + I+ ++ GGPA+ SG+L GDQI+S+NG L Sbjct: 31 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSL 62 >4QL6-A nrPDB Length = 634 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 29/77 (37%), Positives = 45/77 (58%), Gaps = 3/77 (3%) Query: 313 RIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 R + +G G+G +V ED +G+ + +LAGGPAD +G LR GD I VNG ++ N Sbjct: 229 RAQLEKGMCGIG--VVLKEDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIENTPF 286 Query: 373 EQAAIALKNA-GQTVTI 388 +L+ + G +VT+ Sbjct: 287 PGVLDSLRGSPGSSVTL 303 Score = 33.1 bits (74), Expect = 0.44, Method: Compositional matrix adjust. Identities = 23/85 (27%), Positives = 41/85 (48%), Gaps = 9/85 (10%) Query: 68 LERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 LE+G G+G + D + + +++ GG A + G LRV D I VN ++ Sbjct: 232 LEKGMCGIGVVLKEDID--------GVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIEN 283 Query: 128 VTHSAAVEALKEA-GSIVRLYVMRR 151 +++L+ + GS V L + R+ Sbjct: 284 TPFPGVLDSLRGSPGSSVTLDIHRQ 308 Score = 32.3 bits (72), Expect = 0.85, Method: Compositional matrix adjust. Identities = 19/65 (29%), Positives = 32/65 (49%), Gaps = 8/65 (12%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 M +L KG G+G + + + + V +++ GG A K G L++GD I VN Sbjct: 228 MRAQLEKGMCGIGVVLKEDI--------DGVVVKEVLAGGPADKTGSLRVGDIIYRVNGK 279 Query: 219 GLEDV 223 +E+ Sbjct: 280 NIENT 284 >3CH8-A nrPDB Length = 195 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 5/79 (6%) Query: 170 LGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHE 226 LGFSI+GGVG N P D+ I+VT++ G A K LQ GDKI+ N ++ H Sbjct: 5 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHG 62 Query: 227 DAVAALKNTYDVVYLKVAK 245 AV+ LK + V L + + Sbjct: 63 QAVSLLKTFQNTVELIIVR 81 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/83 (36%), Positives = 43/83 (51%), Gaps = 5/83 (6%) Query: 71 GNSGLGFSIAGGTD---NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 G+ LGFSI+GG NP DD IF+T++ P G A++ L+ D I+ N Sbjct: 1 GSPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFIN 58 Query: 128 VTHSAAVEALKEAGSIVRLYVMR 150 + H AV LK + V L ++R Sbjct: 59 IEHGQAVSLLKTFQNTVELIIVR 81 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 31/80 (38%), Positives = 40/80 (50%), Gaps = 11/80 (13%) Query: 319 GSTGLGFNIVGGEDG---------EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 GS LGF+I GG G +GIF++ + GPA S L+ GD+I+ NG N Sbjct: 1 GSPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPA--SKLLQPGDKIIQANGYSFIN 58 Query: 370 ASHEQAAIALKNAGQTVTII 389 H QA LK TV +I Sbjct: 59 IEHGQAVSLLKTFQNTVELI 78 >4DEX-A nrPDB Length = 339 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 65/290 (22%), Positives = 113/290 (38%), Gaps = 38/290 (13%) Query: 430 GFYIRALFDYDKTK--DCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y D A+SF D LHV + + +WW R V E IGF Sbjct: 40 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCE---IGF 96 Query: 488 IPSKRRVER-REWSRLKAKDWGSSSGSQ-----GREDSVLSYETVTQMEVHYARPIIILG 541 IPS ++E R +AK++ S + + + Y+ V M RP++++G Sbjct: 97 IPSPVKLENMRLQHEQRAKEFKLHSKEKRMPFFKKTEHTPPYDVVPSM-----RPVVLVG 151 Query: 542 PT------KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQA 595 P+ D L +F + TR + + R S+ Sbjct: 152 PSLKGYEVTDMMQKALFDFLKHRFEGRI-SITRVTADISLAKRSVLNNPSK--------- 201 Query: 596 HKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR- 651 H IE S L + ++ + E+A + +LD + N +L L PI ++++ Sbjct: 202 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIVVYVKI 261 Query: 652 --PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEE 699 P+ L+ +++ + + A KL Q E F I++ + E+ Sbjct: 262 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLED 311 >2VZ5-A nrPDB Length = 139 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 9/86 (10%) Query: 170 LGFSIAGGVGN-------QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 LGFSI GG+ D IYVT++ EGG A G LQIGDKI+ VN + Sbjct: 40 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 98 Query: 223 VMHEDAVAAL-KNTYDVVYLKVAKPS 247 V H+ A L K + +VV L V + S Sbjct: 99 VTHDQARKRLTKRSEEVVRLLVTRQS 124 Score = 48.9 bits (115), Expect = 7e-06, Method: Compositional matrix adjust. Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 9/85 (10%) Query: 75 LGFSIAGGTD-----NPHIGD--DPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 LGFSI GG D NP D D I++T++ GG A G L++ D I+ VN D+ Sbjct: 40 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 98 Query: 128 VTHSAAVEAL-KEAGSIVRLYVMRR 151 VTH A + L K + +VRL V R+ Sbjct: 99 VTHDQARKRLTKRSEEVVRLLVTRQ 123 Score = 47.4 bits (111), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 29/81 (35%), Positives = 47/81 (58%), Gaps = 18/81 (22%) Query: 312 RRIVIHRGSTG----LGFNIVGGEDGE-------------GIFISFILAGGPADLSGELR 354 +R+ IH+ G LGF+I GG D + GI+++ + GGPA+++G L+ Sbjct: 25 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 83 Query: 355 KGDQILSVNGVDLRNASHEQA 375 GD+I+ VNG D+ +H+QA Sbjct: 84 IGDKIMQVNGWDMTMVTHDQA 104 >2QBW-A nrPDB Length = 195 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 32/79 (40%), Positives = 44/79 (55%), Gaps = 5/79 (6%) Query: 170 LGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHE 226 LGFSI+GGVG N P D+ I+VT++ G A K LQ GDKI+ N ++ H Sbjct: 4 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHG 61 Query: 227 DAVAALKNTYDVVYLKVAK 245 AV+ LK + V L + + Sbjct: 62 QAVSLLKTFQNTVELIIVR 80 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 29/79 (36%), Positives = 41/79 (51%), Gaps = 5/79 (6%) Query: 75 LGFSIAGGTD---NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHS 131 LGFSI+GG NP DD IF+T++ P G A++ L+ D I+ N + H Sbjct: 4 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHG 61 Query: 132 AAVEALKEAGSIVRLYVMR 150 AV LK + V L ++R Sbjct: 62 QAVSLLKTFQNTVELIIVR 80 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 29/76 (38%), Positives = 38/76 (50%), Gaps = 11/76 (14%) Query: 323 LGFNIVGGEDG---------EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 LGF+I GG G +GIF++ + GPA S L+ GD+I+ NG N H Sbjct: 4 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPA--SKLLQPGDKIIQANGYSFINIEHG 61 Query: 374 QAAIALKNAGQTVTII 389 QA LK TV +I Sbjct: 62 QAVSLLKTFQNTVELI 77 >2L4S-A nrPDB Length = 124 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 36/86 (41%), Positives = 45/86 (52%), Gaps = 9/86 (10%) Query: 170 LGFSIAGGVGN-------QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 LGFSI GG+ D IYVT++ EGG A G LQIGDKI+ VN + Sbjct: 29 LGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWDMTM 87 Query: 223 VMHEDAVAAL-KNTYDVVYLKVAKPS 247 V H+ A L K + +VV L V + S Sbjct: 88 VTHDQARKRLTKRSEEVVRLLVTRQS 113 Score = 48.5 bits (114), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 36/88 (40%), Positives = 48/88 (54%), Gaps = 9/88 (10%) Query: 72 NSGLGFSIAGGTD-----NPHIGD--DPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVD 124 N LGFSI GG D NP D D I++T++ GG A G L++ D I+ VN D Sbjct: 26 NLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQIGDKIMQVNGWD 84 Query: 125 VREVTHSAAVEAL-KEAGSIVRLYVMRR 151 + VTH A + L K + +VRL V R+ Sbjct: 85 MTMVTHDQARKRLTKRSEEVVRLLVTRQ 112 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 23/91 (25%) Query: 307 IPREP-----RRIVIHRGSTG----LGFNIVGGEDGE-------------GIFISFILAG 344 IP +P +R+ IH+ G LGF+I GG D + GI+++ + G Sbjct: 4 IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63 Query: 345 GPADLSGELRKGDQILSVNGVDLRNASHEQA 375 GPA+++G L+ GD+I+ VNG D+ +H+QA Sbjct: 64 GPAEIAG-LQIGDKIMQVNGWDMTMVTHDQA 93 >2F3T-A nrPDB Length = 207 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 41/153 (26%), Positives = 70/153 (45%), Gaps = 11/153 (7%) Query: 562 CVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAE 621 V HTTR R E+ G Y FV+ E E I F+E + + YGTS +++ +V Sbjct: 36 SVSHTTRQPRPGEVHGEHYFFVNHDEFKEM-ISRDAFLEHAEVFGNYYGTSREAIEQVLA 94 Query: 622 QGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI------TEEQARKAFD 675 G LD+ ++++ H +IFI P S +E+++R+ +EE K Sbjct: 95 TGVDVFLDIDWQGAQQIRQKMPHARSIFILPPS---KIELDRRLRGRGQDSEEVIAKRMA 151 Query: 676 RATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 708 +A + E + ++ D F+ +K +I Sbjct: 152 QAVAEMSHYAE-YDYLIVNDDFDTALTDLKTII 183 >3K1R-A nrPDB Length = 192 Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 29/68 (42%), Positives = 44/68 (64%), Gaps = 3/68 (4%) Query: 322 GLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALK 380 GLG ++ GG E G G+FIS ++ GG AD G L+ GD+I+ +NG + + +HE+ I L Sbjct: 97 GLGLSVRGGLEFGCGLFISHLIKGGQADSVG-LQVGDEIVRINGYSISSCTHEE-VINLI 154 Query: 381 NAGQTVTI 388 +TV+I Sbjct: 155 RTEKTVSI 162 Score = 42.4 bits (98), Expect = 7e-04, Method: Compositional matrix adjust. Identities = 34/122 (27%), Positives = 65/122 (53%), Gaps = 12/122 (9%) Query: 155 AEKVMEIKLIK-GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKIL 213 + K+ E++L + P+GLG S+ GG + ++++ +I+GG A G LQ+GD+I+ Sbjct: 82 SRKLKEVRLDRLHPEGLGLSVRGG-----LEFGCGLFISHLIKGGQADSVG-LQVGDEIV 135 Query: 214 AVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEIS 273 +N + HE+ + ++ T V +KV + L + PD ++ Q++D +S Sbjct: 136 RINGYSISSCTHEEVINLIR-TEKTVSIKV---RHIGLIPVKSSPDEPLTW-QYVDQFVS 190 Query: 274 HS 275 S Sbjct: 191 ES 192 >2KBS-A nrPDB Length = 92 Score = 48.9 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 35/86 (40%), Positives = 48/86 (55%), Gaps = 7/86 (8%) Query: 309 REPRRIVIHRGSTGLGFNIVGGE-DGEGIFISFILAGGPADLSGE--LRKGDQILSVNGV 365 +E + + GS GLG +I G GIFIS + P LS E L GDQI+ VNGV Sbjct: 1 KEKKVFISLVGSRGLGCSISSGPIQKPGIFISHV---KPGSLSAEVGLEIGDQIVEVNGV 57 Query: 366 DLRNASHEQAAIALKNAGQ-TVTIIA 390 D N H++A LK++ T++I+A Sbjct: 58 DFSNLDHKEAVNVLKSSRSLTISIVA 83 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 71 GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 G+ GLG SI+ G P IFI+ + PG +A+ G L + D I+ VN VD + H Sbjct: 11 GSRGLGCSISSGPIQ-----KPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSNLDH 64 Query: 131 SAAVEALKEAGSI 143 AV LK + S+ Sbjct: 65 KEAVNVLKSSRSL 77 Score = 40.4 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 29/80 (36%), Positives = 49/80 (61%), Gaps = 7/80 (8%) Query: 156 EKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 EK + I L+ G +GLG SI+ G + PG I+++ + G + + G L+IGD+I+ V Sbjct: 2 EKKVFISLV-GSRGLGCSISSGPIQK--PG---IFISHVKPGSLSAEVG-LEIGDQIVEV 54 Query: 216 NSVGLEDVMHEDAVAALKNT 235 N V ++ H++AV LK++ Sbjct: 55 NGVDFSNLDHKEAVNVLKSS 74 >3LNC-A nrPDB Length = 231 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 37/171 (21%), Positives = 77/171 (45%), Gaps = 4/171 (2%) Query: 541 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE 600 G K + LL + + V TTR R+ E +G+DY+FV RE+ + + IE Sbjct: 37 GCGKTTVANKLLEKQKNNIVKSVSVTTRAARKGEKEGKDYYFV-DREEFLRLCSNGEIIE 95 Query: 601 AGQYNSHLYGTSVQSVREVAEQGKHCILDVS-ANAVRRLQAAHLHPIAIFIRPRSLENVL 659 + + YG +++ + ++G +L + A + ++ H ++IFI P S+E + Sbjct: 96 HAEVFGNFYGVPRKNLEDNVDKGVSTLLVIDWQGAFKFMEMMREHVVSIFIMPPSMEELR 155 Query: 660 E--INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 708 +R + + +A + E E + ++ + EE ++ ++ Sbjct: 156 RRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIEETADRISNIL 206 >1X5N-A nrPDB Length = 114 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 36/93 (38%), Positives = 50/93 (53%), Gaps = 7/93 (7%) Query: 309 REPRRIVIHRGSTGLGFNIVGGE-DGEGIFISFILAGGPADLSGE--LRKGDQILSVNGV 365 +E + + GS GLG +I G GIFIS + P LS E L GDQI+ VNGV Sbjct: 15 KEKKVFISLVGSRGLGCSISSGPIQKPGIFISHVK---PGSLSAEVGLEIGDQIVEVNGV 71 Query: 366 DLRNASHEQAAIALKNA-GQTVTIIAQYKPEEY 397 D N H++A LK++ T++I+A E + Sbjct: 72 DFSNLDHKEAVNVLKSSRSLTISIVAAAGRELF 104 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 71 GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 G+ GLG SI+ G P IFI+ + PG +A+ G L + D I+ VN VD + H Sbjct: 25 GSRGLGCSISSGPI-----QKPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSNLDH 78 Query: 131 SAAVEALKEAGSI 143 AV LK + S+ Sbjct: 79 KEAVNVLKSSRSL 91 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 32/103 (31%), Positives = 58/103 (56%), Gaps = 8/103 (7%) Query: 156 EKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 EK + I L+ G +GLG SI+ G + PG I+++ + G + + G L+IGD+I+ V Sbjct: 16 EKKVFISLV-GSRGLGCSISSGPIQK--PG---IFISHVKPGSLSAEVG-LEIGDQIVEV 68 Query: 216 NSVGLEDVMHEDAVAALKNTYDV-VYLKVAKPSNAYLSDSYAP 257 N V ++ H++AV LK++ + + + A +++D P Sbjct: 69 NGVDFSNLDHKEAVNVLKSSRSLTISIVAAAGRELFMTDRSGP 111 >1UEW-A nrPDB Length = 114 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 9/84 (10%) Query: 314 IVIHRGST-GLGFNIVGG----EDGEGIF----ISFILAGGPADLSGELRKGDQILSVNG 364 +VIHR G GF I+ E G I I I+ G PAD +L+ GD+IL+VNG Sbjct: 14 VVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNG 73 Query: 365 VDLRNASHEQAAIALKNAGQTVTI 388 + N H +K+AG +VT+ Sbjct: 74 QSIINMPHADIVKLIKDAGLSVTL 97 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 33/53 (62%) Query: 191 VTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKV 243 + +II+G A + +L++GD+ILAVN + ++ H D V +K+ V L++ Sbjct: 47 IGRIIDGSPADRCAKLKVGDRILAVNGQSIINMPHADIVKLIKDAGLSVTLRI 99 >1S4Q-A nrPDB Length = 228 Score = 46.6 bits (109), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 27/98 (27%), Positives = 48/98 (48%), Gaps = 3/98 (3%) Query: 563 VPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLY--GTSVQSVREVA 620 V TTR R E+DG DYHF+ + ++ I + +E + + L+ GT Q VR A Sbjct: 54 VSATTRAPRPGEVDGVDYHFIDP-TRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAA 112 Query: 621 EQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENV 658 G +++V R ++ + +F+ P S +++ Sbjct: 113 ATGVPVLIEVDLAGARAIKKTMPEAVTVFLAPPSWQDL 150 >3TR0-A nrPDB Length = 205 Score = 45.8 bits (107), Expect = 6e-05, Method: Compositional matrix adjust. Identities = 42/153 (27%), Positives = 73/153 (47%), Gaps = 11/153 (7%) Query: 562 CVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE-AGQYNSHLYGTSVQSVREVA 620 + HTTRPKR + +G DY F+ + + ++ F+E A Y H YGT V Sbjct: 37 SISHTTRPKRPGDQEGVDYFFIDE-TRFQAMVKEGAFLEHATIYERH-YGTEKDWVLRQL 94 Query: 621 EQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE-INKRITEEQA----RKAFD 675 + G+ +L++ R+++ ++IFI P S+E + E + KR ++ A R A Sbjct: 95 KAGRDVLLEIDWQGARQIRELFPPALSIFILPPSIEALRERLIKRRQDDTAIIEQRLALA 154 Query: 676 RATKLEQEFTECFSAIVEGDSFEEIYHKVKRVI 708 R E + F +V D+F++ + +I Sbjct: 155 RE---EMAHYKEFDYLVVNDNFDQAVQNLIHII 184 >4ZW2-A nrPDB Length = 333 Score = 45.4 bits (106), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 60/279 (21%), Positives = 108/279 (38%), Gaps = 38/279 (13%) Query: 451 ALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREW--------SRL 502 A++F D LH+ + + +WW R V E +GFIPS +++ +RL Sbjct: 62 AITFEPKDFLHIKEKYNNDWWIGRLVKEGCE---VGFIPSPVKLDSLRLLQEQTLRQNRL 118 Query: 503 KAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPT------KDRANDDLLSEFP 556 + G + + V Y+ V M RPII++GP+ D L Sbjct: 119 SSSKHGKRIPFFKKTEHVPPYDVVPSM-----RPIILVGPSLKGYEVTDMMQKALFDFLK 173 Query: 557 DKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHL--YGTSVQ 614 +F + TR + + R S+ H IE S L + ++ Sbjct: 174 HRFDGRI-SITRVTADISLAKRSVLNNPSK---------HIIIERSNTRSSLAEVQSEIE 223 Query: 615 SVREVAEQGKHCILDV-SANAVRRLQAAHLHPIAIFIR---PRSLENVLEINKRITEEQA 670 + E+A + LD + N +L L PI ++I+ P+ L+ +++ + + Sbjct: 224 RIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHL 283 Query: 671 RKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 709 + KL Q E F I++ + E+ + +E Sbjct: 284 NVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEYLE 322 >1X6D-A nrPDB Length = 119 Score = 45.4 bits (106), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 25/89 (28%), Positives = 50/89 (56%), Gaps = 4/89 (4%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 +GLGFS+AGG D ++ I + ++ P G A+Q+G ++ + +L +N ++ TH Sbjct: 27 AGLGFSLAGGADL----ENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHD 82 Query: 133 AVEALKEAGSIVRLYVMRRKPPAEKVMEI 161 A+ L++A + ++ RK E + ++ Sbjct: 83 ALAILRQAREPRQAVIVTRKLTPEAMPDL 111 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 27/79 (34%), Positives = 42/79 (53%), Gaps = 5/79 (6%) Query: 322 GLGFNIVGGEDGEGIFISF--ILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 GLGF++ GG D E I+ + G A G ++KG+++LS+NG L+ +H A L Sbjct: 28 GLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDALAIL 87 Query: 380 KNA---GQTVTIIAQYKPE 395 + A Q V + + PE Sbjct: 88 RQAREPRQAVIVTRKLTPE 106 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 39/65 (60%), Gaps = 4/65 (6%) Query: 169 GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDA 228 GLGFS+AGG + + I V ++ G A ++G +Q G+++L++N L+ H DA Sbjct: 28 GLGFSLAGGADLE----NKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLKGTTHHDA 83 Query: 229 VAALK 233 +A L+ Sbjct: 84 LAILR 88 >1UEP-A nrPDB Length = 103 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/89 (33%), Positives = 45/89 (50%), Gaps = 11/89 (12%) Query: 56 GTEGEMEYEE--ITLERGNSGLGFSIAGGTDNPHIGDDPS--IFITKIIPGGAAAQDGRL 111 G+ G Y+E + L R SG GF I GG D+P I I +I G+A +DGRL Sbjct: 1 GSSGSSGYKELDVHLRRMESGFGFRILGG-------DEPGQPILIGAVIAMGSADRDGRL 53 Query: 112 RVNDSILFVNEVDVREVTHSAAVEALKEA 140 D +++V+ + V TH ++ + A Sbjct: 54 HPGDELVYVDGIPVAGKTHRYVIDLMHHA 82 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 22/59 (37%), Positives = 35/59 (59%), Gaps = 1/59 (1%) Query: 316 IHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 + R +G GF I+GG E G+ I I ++A G AD G L GD+++ V+G+ + +H Sbjct: 15 LRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTHR 73 Score = 32.3 bits (72), Expect = 0.82, Method: Compositional matrix adjust. Identities = 25/80 (31%), Positives = 40/80 (50%), Gaps = 13/80 (16%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 K +++ L + G GF I GG PG I + +I G+A +DGRL GD+++ V+ Sbjct: 9 KELDVHLRRMESGFGFRILGG----DEPG-QPILIGAVIAMGSADRDGRLHPGDELVYVD 63 Query: 217 SVGLE--------DVMHEDA 228 + + D+MH A Sbjct: 64 GIPVAGKTHRYVIDLMHHAA 83 >3QDO-A nrPDB Length = 109 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 33/92 (35%), Positives = 49/92 (53%), Gaps = 15/92 (16%) Query: 311 PRRIVIHRGSTGLGFNIVGGEDGEGIF-------------ISFILAGGPADLSGELRKGD 357 PR + I + +G GFN+ G G +S +L GG AD +G +RKGD Sbjct: 7 PRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGD 65 Query: 358 QILSVNGVDLRNASHEQAAIALKNAGQTVTII 389 +IL VNGV++ A+H+Q + L AG+ I+ Sbjct: 66 RILEVNGVNVEGATHKQ-VVDLIRAGEKELIL 96 >1N7E-A nrPDB Length = 97 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 31/91 (34%), Positives = 51/91 (56%), Gaps = 7/91 (7%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +E+K GP LG +I+G P D I ++ + +GG A + G + IGD+ILA+NS Sbjct: 9 VELKRYGGP--LGITISG----TEEPFD-PIIISSLTKGGLAERTGAIHIGDRILAINSS 61 Query: 219 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 249 L+ +A+ L+ + V LK+ K ++A Sbjct: 62 SLKGKPLSEAIHLLQMAGETVTLKIKKQTDA 92 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 25/67 (37%), Positives = 39/67 (58%), Gaps = 1/67 (1%) Query: 323 LGFNIVGGEDG-EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKN 381 LG I G E+ + I IS + GG A+ +G + GD+IL++N L+ +A L+ Sbjct: 18 LGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKPLSEAIHLLQM 77 Query: 382 AGQTVTI 388 AG+TVT+ Sbjct: 78 AGETVTL 84 >5A2P-A nrPDB Length = 163 Score = 43.9 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Query: 335 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-GQTVTIIAQYK 393 GIF+ + A PA L G LR GDQ+L +NG + S ++A LK A G+ +T+ + + Sbjct: 26 GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR 84 Query: 394 PEE 396 P E Sbjct: 85 PFE 87 >5G1D-A nrPDB Length = 201 Score = 43.5 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 25/63 (39%), Positives = 37/63 (58%), Gaps = 2/63 (3%) Query: 335 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-GQTVTIIAQYK 393 GIF+ + A PA L G LR GDQ+L +NG + S ++A LK A G+ +T+ + + Sbjct: 38 GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR 96 Query: 394 PEE 396 P E Sbjct: 97 PFE 99 >1VYT-A nrPDB Length = 351 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 36/134 (26%), Positives = 54/134 (40%), Gaps = 28/134 (20%) Query: 430 GFYIRALFDYDKTKD--CGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y D C ++F D LH+ + +WW R V E DI F Sbjct: 46 AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLV---KEGGDIAF 102 Query: 488 IPSKRRVER-REWSRLKAKDWGSSSG-----------------SQGREDSVLSYETVTQM 529 IPS +R+E R KA+ G+ S Q + + V Y+ V M Sbjct: 103 IPSPQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSM 162 Query: 530 EVHYARPIIILGPT 543 RP++++GP+ Sbjct: 163 -----RPVVLVGPS 171 >1GCQ-A nrPDB Length = 61 Score = 43.1 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 18/42 (42%), Positives = 25/42 (59%), Gaps = 5/42 (11%) Query: 432 YIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 Y++ALFD+D +D L FR GD +HV+D D WW+ Sbjct: 4 YVQALFDFDPQED-----GELGFRRGDFIHVMDNSDPNWWKG 40 >5N7D-A nrPDB Length = 427 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 26/74 (35%), Positives = 39/74 (52%), Gaps = 5/74 (6%) Query: 308 PREPRRIVIH----RGSTGLGFNIVGGED-GEGIFISFILAGGPADLSGELRKGDQILSV 362 P E + IH + S G GF +VGG++ E + I ++ GPA L G++ GD I+SV Sbjct: 12 PSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSV 71 Query: 363 NGVDLRNASHEQAA 376 N + +H Q Sbjct: 72 NDTCVLGHTHAQVV 85 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/101 (29%), Positives = 50/101 (49%), Gaps = 7/101 (6%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 N +E + ++ L + + G GF++ GG D P D + I ++ G AA DG++ Sbjct: 11 NPSELKGKFIHTKLRKSSRGFGFTVVGG-DEP----DEFLQIKSLVLDGPAALDGKMETG 65 Query: 115 DSILFVNEVDVREVTHSAAVEALKE--AGSIVRLYVMRRKP 153 D I+ VN+ V TH+ V+ + G+ V L + R P Sbjct: 66 DVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYP 106 Score = 35.8 bits (81), Expect = 0.062, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 41/86 (47%), Gaps = 8/86 (9%) Query: 152 KPPAE---KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQI 208 + P+E K + KL K +G GF++ GG D + + ++ G A DG+++ Sbjct: 10 RNPSELKGKFIHTKLRKSSRGFGFTVVGGD-----EPDEFLQIKSLVLDGPAALDGKMET 64 Query: 209 GDKILAVNSVGLEDVMHEDAVAALKN 234 GD I++VN + H V ++ Sbjct: 65 GDVIVSVNDTCVLGHTHAQVVKIFQS 90 >1GRI-A nrPDB Length = 217 Score = 42.7 bits (99), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 5/47 (10%) Query: 427 PKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 P++ Y++ALFD+D +D L FR GD +HV+D D WW+ Sbjct: 155 PQQPTYVQALFDFDPQEDG-----ELGFRRGDFIHVMDNSDPNWWKG 196 >1NF3-C nrPDB Length = 128 Score = 42.7 bits (99), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 24/55 (43%), Positives = 33/55 (60%), Gaps = 4/55 (7%) Query: 75 LGFSIAGGTD---NPH-IGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 LGF I G+ PH + P IFI++++PGG A G L VND +L VN ++V Sbjct: 44 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEV 98 Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 50/100 (50%), Gaps = 13/100 (13%) Query: 289 TSPRRYSPVAKDLLGEEDIPREPRRIVIHRGST--GLGFNIVGG----------EDGEGI 336 + P+ + PV+ ++ + +P RR+ + + T LGF I G E GI Sbjct: 9 SMPQDFRPVS-SIIDVDILPETHRRVRLCKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGI 67 Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAA 376 FIS ++ GG A +G L D++L VNG+++ S +Q Sbjct: 68 FISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVT 107 >1UJD-A nrPDB Length = 117 Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 25/59 (42%), Positives = 39/59 (66%), Gaps = 6/59 (10%) Query: 322 GLGFNIVGGED-----GE-GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 GLG IVGG++ GE G +I+ IL GG A+ +G+L +G Q+L NG+ L + ++E+ Sbjct: 31 GLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTYEE 89 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 31/59 (52%) Query: 72 NSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 +GLG I GG + P + +I KI+PGG+A Q G+L +L N + + T+ Sbjct: 29 GNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTY 87 Score = 35.4 bits (80), Expect = 0.088, Method: Compositional matrix adjust. Identities = 22/62 (35%), Positives = 34/62 (54%), Gaps = 6/62 (9%) Query: 169 GLGFSIAGGVGNQHIPGDNS---IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMH 225 GLG I GG + IPG + Y+ KI+ GG+A + G+L G ++L N + L + Sbjct: 31 GLGIRIVGG---KEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTY 87 Query: 226 ED 227 E+ Sbjct: 88 EE 89 >1UF1-A nrPDB Length = 128 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 28/61 (45%), Positives = 37/61 (60%), Gaps = 2/61 (3%) Query: 323 LGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKN 381 LG I GG E G GI+I+ + G A+ SG L+ GDQIL VNG N H++A LK+ Sbjct: 34 LGLTIRGGAEYGLGIYITGVDPGSEAEGSG-LKVGDQILEVNGRSFLNILHDEAVRLLKS 92 Query: 382 A 382 + Sbjct: 93 S 93 Score = 36.6 bits (83), Expect = 0.040, Method: Compositional matrix adjust. Identities = 28/85 (32%), Positives = 48/85 (56%), Gaps = 7/85 (8%) Query: 156 EKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 EK + + L G + LG +I GG ++ G IY+T + G A G L++GD+IL V Sbjct: 21 EKKVNLVLGDG-RSLGLTIRGGA--EYGLG---IYITGVDPGSEAEGSG-LKVGDQILEV 73 Query: 216 NSVGLEDVMHEDAVAALKNTYDVVY 240 N +++H++AV LK++ ++ Sbjct: 74 NGRSFLNILHDEAVRLLKSSRHLIL 98 >2LC7-A nrPDB Length = 102 Score = 40.4 bits (93), Expect = 0.003, Method: Compositional matrix adjust. Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 4/55 (7%) Query: 75 LGFSIAGGTD----NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 LGF I GT + P IFI++++PGG A G L VND ++ VN ++V Sbjct: 19 LGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEV 73 Score = 34.3 bits (77), Expect = 0.20, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 37/74 (50%), Gaps = 10/74 (13%) Query: 313 RIVIHRGSTGLGFNIVGG----------EDGEGIFISFILAGGPADLSGELRKGDQILSV 362 R++ H LGF I G E GIFIS ++ GG A+ +G L D+++ V Sbjct: 9 RLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEV 68 Query: 363 NGVDLRNASHEQAA 376 NG+++ + +Q Sbjct: 69 NGIEVAGKTLDQVT 82 >1RY4-A nrPDB Length = 128 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 4/55 (7%) Query: 75 LGFSIAGGTD----NPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 LGF I GT + P IFI++++PGG A G L VND ++ VN ++V Sbjct: 45 LGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEV 99 Score = 35.8 bits (81), Expect = 0.071, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 50/109 (45%), Gaps = 16/109 (14%) Query: 280 TDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVI--HRGSTGLGFNIVGG------- 330 T P+ P R+ S + + + +P RR+ + H LGF I G Sbjct: 4 TKAPSISIPHDFRQVSAI----IDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTA 59 Query: 331 ---EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAA 376 E GIFIS ++ GG A+ +G L D+++ VNG+++ + +Q Sbjct: 60 SGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVT 108 >2EYZ-A nrPDB Length = 304 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 10/58 (17%) Query: 432 YIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIP 489 Y+RALFD++ + + L F+ GD+L + D +E+WW A DSE G IP Sbjct: 136 YVRALFDFNGNDE-----EDLPFKKGDILRIRDKPEEQWWNA----EDSEGKR-GMIP 183 >1VYV-A nrPDB Length = 359 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 23/58 (39%), Positives = 29/58 (50%), Gaps = 10/58 (17%) Query: 445 CGFL-------SQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVE 495 CG L S A+SF D LH+ + + +WW R V E IGFIPS R+E Sbjct: 55 CGALDEDVPVPSSAVSFDAKDFLHIKEKYNNDWWIGRLVKEGCE---IGFIPSPLRLE 109 >2LQW-A nrPDB Length = 303 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 33/135 (24%), Positives = 58/135 (42%), Gaps = 14/135 (10%) Query: 432 YIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSK 491 Y+R L+D+ G ++ L F+ G++L +I+ +E+WW AR ++ +G IP Sbjct: 127 YVRTLYDFP-----GNDAEDLPFKKGEILVIIEKPEEQWWSAR-----NKDGRVGMIPVP 176 Query: 492 RRVERREWSRLKAKDWGSSSGSQGREDSVLSY---ETVTQMEVHYARPIIILGPTKDRAN 548 VE+ S K +S S G + +Y +T T + P + P N Sbjct: 177 -YVEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQN 235 Query: 549 DDLLSEFPDKFGSCV 563 + ++ K C Sbjct: 236 GPVFAKAIQKRVPCA 250 >1ZUB-A nrPDB Length = 114 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 4/57 (7%) Query: 323 LGFNIVGGEDGE----GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQA 375 LG +VGG+ + G FI+ + G AD+ G LR GD++L NG L A++E+ Sbjct: 39 LGLKVVGGKMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEV 95 >1U37-A nrPDB Length = 89 Score = 39.3 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 16/32 (50%), Positives = 24/32 (75%) Query: 336 IFISFILAGGPADLSGELRKGDQILSVNGVDL 367 + I+ ++ GGPA+ SG+L GDQI+S+NG L Sbjct: 31 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSL 62 Score = 36.2 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 17/50 (34%), Positives = 29/50 (58%), Gaps = 3/50 (6%) Query: 188 SIYVTKIIEGGAAHKDGRLQIGDKILAVNS---VGLEDVMHEDAVAALKN 234 ++ + ++ GG A K G+L IGD+I+++N VGL + + LKN Sbjct: 30 TVIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKN 79 Score = 29.6 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 19/30 (63%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVN 121 P++ I ++ GG A + G+L + D I+ +N Sbjct: 29 PTVIIANMMHGGPAEKSGKLNIGDQIMSIN 58 >2V90-A nrPDB Length = 96 Score = 38.5 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 27/86 (31%), Positives = 44/86 (51%), Gaps = 4/86 (4%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 + L KGP+G GF + G PG ++ ++ G A K G +Q GD+++AV + Sbjct: 7 LHLEKGPQGFGFLLREEKGLDGRPGQ---FLWEVDPGLPAKKAG-MQAGDRLVAVAGESV 62 Query: 221 EDVMHEDAVAALKNTYDVVYLKVAKP 246 E + HE+ V+ ++ V L V P Sbjct: 63 EGLGHEETVSRIQGQGSCVSLTVVDP 88 Score = 32.7 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 23/82 (28%), Positives = 43/82 (52%), Gaps = 4/82 (4%) Query: 310 EPRRIVIHRGSTGLGFNI--VGGEDGE-GIFISFILAGGPADLSGELRKGDQILSVNGVD 366 +PR + + +G G GF + G DG G F+ + G PA +G ++ GD++++V G Sbjct: 3 KPRCLHLEKGPQGFGFLLREEKGLDGRPGQFLWEVDPGLPAKKAG-MQAGDRLVAVAGES 61 Query: 367 LRNASHEQAAIALKNAGQTVTI 388 + HE+ ++ G V++ Sbjct: 62 VEGLGHEETVSRIQGQGSCVSL 83 >2EDP-A nrPDB Length = 100 Score = 38.1 bits (87), Expect = 0.013, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 45/77 (58%), Gaps = 2/77 (2%) Query: 318 RGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAA 376 +G GF + GG E E + +S I GG A LS ++R GD+++++NG L S ++A Sbjct: 18 QGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLY-GSRQEAL 76 Query: 377 IALKNAGQTVTIIAQYK 393 I +K + + + +I + + Sbjct: 77 ILIKGSFRILKLIVRRR 93 Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 45/82 (54%), Gaps = 6/82 (7%) Query: 164 IKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDV 223 ++G GF++ GG+ +H + V+KI +GG A +++ GD+++ +N L Sbjct: 17 LQGGAPWGFTLKGGL--EHC---EPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG- 70 Query: 224 MHEDAVAALKNTYDVVYLKVAK 245 ++A+ +K ++ ++ L V + Sbjct: 71 SRQEALILIKGSFRILKLIVRR 92 >1WFG-A nrPDB Length = 131 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 27/77 (35%), Positives = 37/77 (48%), Gaps = 14/77 (18%) Query: 323 LGFNIVGGEDGEG----IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIA 378 LG +VGG+ E FI+ + G AD G LR GD++L NG L+ A+ E Sbjct: 50 LGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFE----- 104 Query: 379 LKNAGQTVTIIAQYKPE 395 + II + KPE Sbjct: 105 -----EVYNIILESKPE 116 >3PV2-A nrPDB Length = 451 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 26/87 (29%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 331 EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIA 390 ED +G +S + PA+L+G L+ GD I +N + A+ + I+L G TV II Sbjct: 279 EDFQGALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVKTTISLLRVGSTVKIIV 337 Query: 391 Q--YKPEEYSRFEAKIHDLREQLMNSS 415 + KP S I ++L +++ Sbjct: 338 ERDNKPLTLSAVVTDIKSHEQKLQSNN 364 >1VA8-A nrPDB Length = 113 Score = 37.7 bits (86), Expect = 0.020, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 32/54 (59%) Query: 336 IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTII 389 + IS I+ GG A+ SG L +GD++L +NG+++R + L + T+T + Sbjct: 50 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 103 Score = 35.4 bits (80), Expect = 0.079, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 39/66 (59%), Gaps = 3/66 (4%) Query: 187 NSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL--EDVMHE-DAVAALKNTYDVVYLKV 243 +S+ +++I++GGAA K G L GD++L +N + + +DV D ++ + T V + Sbjct: 48 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 107 Query: 244 AKPSNA 249 + PS+ Sbjct: 108 SGPSSG 113 >4UU6-A nrPDB Length = 90 Score = 37.4 bits (85), Expect = 0.024, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 32/54 (59%) Query: 336 IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTII 389 + IS I+ GG A+ SG L +GD++L +NG+++R + L + T+T + Sbjct: 33 VIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFV 86 Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust. Identities = 13/32 (40%), Positives = 24/32 (75%) Query: 187 NSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +S+ +++I++GGAA K G L GD++L +N + Sbjct: 31 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGI 62 >1P1E-A nrPDB Length = 101 Score = 37.0 bits (84), Expect = 0.030, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 32/49 (65%) Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQT 385 IS+I A PA+ G L+ GD+++++NG+ +++ E+A L+++ T Sbjct: 39 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSIT 87 Score = 33.5 bits (75), Expect = 0.35, Method: Compositional matrix adjust. Identities = 22/80 (27%), Positives = 38/80 (47%), Gaps = 2/80 (2%) Query: 157 KVMEIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 + E+ L P G G + G V + ++ I A + G LQIGD+++A+ Sbjct: 6 ETTEVVLTADPVTGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMAI 64 Query: 216 NSVGLEDVMHEDAVAALKNT 235 N + ED E+A L+++ Sbjct: 65 NGIPTEDSTFEEANQLLRDS 84 >1V5Q-A nrPDB Length = 122 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 32/49 (65%) Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQT 385 IS+I A PA+ G L+ GD+++++NG+ +++ E+A L+++ T Sbjct: 48 LISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEANQLLRDSSIT 96 Score = 33.1 bits (74), Expect = 0.43, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 2/77 (2%) Query: 160 EIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 E+ L P G G + G V + ++ I A + G LQIGD+++A+N + Sbjct: 18 EVVLTADPVTGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMAINGI 76 Query: 219 GLEDVMHEDAVAALKNT 235 ED E+A L+++ Sbjct: 77 PTEDSTFEEANQLLRDS 93 >3PV4-A nrPDB Length = 354 Score = 36.6 bits (83), Expect = 0.039, Method: Compositional matrix adjust. Identities = 23/78 (29%), Positives = 40/78 (51%), Gaps = 2/78 (2%) Query: 331 EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIA 390 ED +G +S + PA+L+G L+ GD I +N + A+ + I+L G TV II Sbjct: 279 EDFQGALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVKTTISLLRVGSTVKIIV 337 Query: 391 QYKPEEYSRFEAKIHDLR 408 + + + A + D++ Sbjct: 338 ERDNKPLT-LSAVVTDIK 354 >1T0J-A nrPDB Length = 132 Score = 36.6 bits (83), Expect = 0.041, Method: Compositional matrix adjust. Identities = 23/68 (33%), Positives = 31/68 (45%), Gaps = 5/68 (7%) Query: 430 GFYIRALFDYDKTK--DCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y + D A+SF D LHV + + +WW R V E IGF Sbjct: 48 AFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCE---IGF 104 Query: 488 IPSKRRVE 495 IPS ++E Sbjct: 105 IPSPVKLE 112 >1UJV-A nrPDB Length = 96 Score = 36.6 bits (83), Expect = 0.042, Method: Composition-based stats. Identities = 29/103 (28%), Positives = 50/103 (48%), Gaps = 13/103 (12%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 +G+ G+ E +T+ +G G GF+IA D+P I + PG L Sbjct: 3 SGSSGQAELMTLTIVKGAQGFGFTIA---DSPTGQRVKQILDIQGCPG--------LCEG 51 Query: 115 DSILFVNEVDVREVTHSAAVEALKEA--GSIVRLYVMRRKPPA 155 D I+ +N+ +V+ ++H+ V+ LK+ GS L + R P+ Sbjct: 52 DLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHRGSGPS 94 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 19/68 (27%), Positives = 33/68 (48%), Gaps = 5/68 (7%) Query: 314 IVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 + I +G+ G GF I G+ + + G P L +GD I+ +N +++N SH Sbjct: 14 LTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPG-----LCEGDLIVEINQQNVQNLSHT 68 Query: 374 QAAIALKN 381 + LK+ Sbjct: 69 EVVDILKD 76 >5E6P-B nrPDB Length = 88 Score = 36.2 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 21/83 (25%), Positives = 40/83 (48%), Gaps = 4/83 (4%) Query: 312 RRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNAS 371 R ++I + G GF + G + + + GG A +G +++GD+I+ VNG + N+S Sbjct: 9 RCVIIQKDQHGFGFTVSGDRI---VLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTNSS 64 Query: 372 HEQAAIALKNAGQTVTIIAQYKP 394 H + +K+ + P Sbjct: 65 HLEVVKLIKSGAYVALTLLGSSP 87 Score = 33.1 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 25/84 (29%), Positives = 41/84 (48%), Gaps = 11/84 (13%) Query: 165 KGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVM 224 K G GF+++G D + V + GGAA K G ++ GD+I+ VN + + Sbjct: 15 KDQHGFGFTVSG---------DRIVLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTNSS 64 Query: 225 HEDAVAALKN-TYDVVYLKVAKPS 247 H + V +K+ Y + L + PS Sbjct: 65 HLEVVKLIKSGAYVALTLLGSSPS 88 >2DLS-A nrPDB Length = 93 Score = 36.2 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 20/72 (27%), Positives = 38/72 (52%), Gaps = 4/72 (5%) Query: 312 RRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNAS 371 R ++I + G GF + G + + + GG A +G +++GD+I+ VNG + N+S Sbjct: 10 RCVIIQKDQHGFGFTVSGDRI---VLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTNSS 65 Query: 372 HEQAAIALKNAG 383 H + +K+ Sbjct: 66 HLEVVKLIKSGA 77 Score = 32.3 bits (72), Expect = 0.79, Method: Composition-based stats. Identities = 21/70 (30%), Positives = 35/70 (50%), Gaps = 10/70 (14%) Query: 165 KGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVM 224 K G GF+++G D + V + GGAA K G ++ GD+I+ VN + + Sbjct: 16 KDQHGFGFTVSG---------DRIVLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTNSS 65 Query: 225 HEDAVAALKN 234 H + V +K+ Sbjct: 66 HLEVVKLIKS 75 >1X5R-A nrPDB Length = 112 Score = 35.4 bits (80), Expect = 0.090, Method: Composition-based stats. Identities = 16/47 (34%), Positives = 28/47 (59%) Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAG 383 + FI PA+ G L+ GD++LS+NG+ + + E+A L++A Sbjct: 48 LVCFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEANQLLRDAA 94 Score = 32.3 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 22/79 (27%), Positives = 37/79 (46%), Gaps = 2/79 (2%) Query: 157 KVMEIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 + E+ L P G G + GG+ + V I A + G LQ+GD++L++ Sbjct: 15 ETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPL-VCFIEPDSPAERCGLLQVGDRVLSI 73 Query: 216 NSVGLEDVMHEDAVAALKN 234 N + ED E+A L++ Sbjct: 74 NGIATEDGTMEEANQLLRD 92 >1M5Z-A nrPDB Length = 91 Score = 35.4 bits (80), Expect = 0.090, Method: Composition-based stats. Identities = 20/64 (31%), Positives = 35/64 (54%), Gaps = 3/64 (4%) Query: 308 PREPRRIVIHR--GSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV 365 P E ++ +++ G GF++ G +G+++ I GP DL G L+ D++L VN V Sbjct: 4 PVELHKVTLYKDSGMEDFGFSVADGLLEKGVYVKNIRPAGPGDLGG-LKPYDRLLQVNHV 62 Query: 366 DLRN 369 R+ Sbjct: 63 RTRD 66 >2PZ1-A nrPDB Length = 466 Score = 35.4 bits (80), Expect = 0.095, Method: Compositional matrix adjust. Identities = 17/40 (42%), Positives = 23/40 (57%), Gaps = 5/40 (12%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQAR 474 AL+D+ D Q L F+ GDV+ V+DA + EWW R Sbjct: 35 ALWDHVTMDD-----QELGFKAGDVIEVMDATNREWWWGR 69 >4YNN-A nrPDB Length = 448 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 26/82 (31%), Positives = 39/82 (47%), Gaps = 10/82 (12%) Query: 316 IHRGSTG---------LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVD 366 IHRG G L ++ ED +G +S + PA L+G L+ GD I+ +N Sbjct: 252 IHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAG-LKSGDVIVQINDTK 310 Query: 367 LRNASHEQAAIALKNAGQTVTI 388 + A+ + I+L AG T I Sbjct: 311 ITQATQVKTTISLLRAGSTAKI 332 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 29/60 (48%) Query: 106 AQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIK 165 AQ L+ D I+ +N+ + + T +L AGS ++ ++R P +E+ IK Sbjct: 292 AQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIK 351 >1UFX-A nrPDB Length = 103 Score = 35.0 bits (79), Expect = 0.13, Method: Compositional matrix adjust. Identities = 23/77 (29%), Positives = 37/77 (48%), Gaps = 6/77 (7%) Query: 161 IKLIKGPKGLGFSIAGGVGN-QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG 219 +++ K LG +I GG Q +P + I GG+AH G+L++G IL VN + Sbjct: 10 VRVKKSAATLGIAIEGGANTRQPLP-----RIVTIQRGGSAHNCGQLKVGHVILEVNGLT 64 Query: 220 LEDVMHEDAVAALKNTY 236 L H +A + + Sbjct: 65 LRGKEHREAARIIAEAF 81 Score = 33.9 bits (76), Expect = 0.29, Method: Compositional matrix adjust. Identities = 25/72 (34%), Positives = 35/72 (48%), Gaps = 2/72 (2%) Query: 316 IHRGSTGLGFNIVGGEDGEGIF--ISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 + + + LG I GG + I I GG A G+L+ G IL VNG+ LR H Sbjct: 12 VKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKEHR 71 Query: 374 QAAIALKNAGQT 385 +AA + A +T Sbjct: 72 EAARIIAEAFKT 83 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 23/75 (30%), Positives = 36/75 (48%), Gaps = 4/75 (5%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +++ + LG +I GG + P I I GG+A G+L+V IL VN + + Sbjct: 10 VRVKKSAATLGIAIEGGANT----RQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTL 65 Query: 126 REVTHSAAVEALKEA 140 R H A + EA Sbjct: 66 RGKEHREAARIIAEA 80 >4YO1-A nrPDB Length = 351 Score = 34.7 bits (78), Expect = 0.17, Method: Compositional matrix adjust. Identities = 28/90 (31%), Positives = 43/90 (47%), Gaps = 12/90 (13%) Query: 316 IHRGSTG---------LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVD 366 IHRG G L ++ ED +G +S + PA L+G L+ GD I+ +N Sbjct: 252 IHRGLMGIFVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAG-LKSGDVIVQINDTK 310 Query: 367 LRNASHEQAAIALKNAGQT--VTIIAQYKP 394 + A+ + I+L AG T + I+ KP Sbjct: 311 ITQATQVKTTISLLRAGSTAKIKILRDNKP 340 Score = 29.6 bits (65), Expect = 5.1, Method: Compositional matrix adjust. Identities = 16/60 (26%), Positives = 29/60 (48%) Query: 106 AQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIK 165 AQ L+ D I+ +N+ + + T +L AGS ++ ++R P +E+ IK Sbjct: 292 AQLAGLKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDNKPLTLDVEVTDIK 351 >1V6B-A nrPDB Length = 118 Score = 34.3 bits (77), Expect = 0.18, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 4/74 (5%) Query: 164 IKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDV 223 IK L ++ GGV + + V+ + EGGAA + G + GD+I+A+N + D Sbjct: 24 IKKEGSLDLALEGGVDSPV----GKVVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDY 79 Query: 224 MHEDAVAALKNTYD 237 +A AAL+ ++ Sbjct: 80 TLAEAEAALQKAWN 93 Score = 32.7 bits (73), Expect = 0.51, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 38/67 (56%), Gaps = 5/67 (7%) Query: 336 IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA----GQTV-TIIA 390 + +S + GG A+ G + KGD+I+++NG + + + +A AL+ A G + ++A Sbjct: 45 VVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDYTLAEAEAALQKAWNQGGDWIDLVVA 104 Query: 391 QYKPEEY 397 P+EY Sbjct: 105 VCPPKEY 111 >2YT7-A nrPDB Length = 101 Score = 33.9 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 22/55 (40%), Positives = 30/55 (54%), Gaps = 7/55 (12%) Query: 318 RGSTGLGFNIVGGEDGEGIF-----ISFILAGGPADLSGELRKGDQILSVNGVDL 367 R GLG +V E G G I+ +L GGPA+ SG L GD++ ++NG L Sbjct: 18 RRGEGLGVALV--ESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSL 70 Score = 30.8 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 18/68 (26%), Positives = 33/68 (48%), Gaps = 3/68 (4%) Query: 168 KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHED 227 +GLG ++ +P + + ++ GG A + G L IGD++ A+N L + Sbjct: 21 EGLGVALVESGWGSLLP---TAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAA 77 Query: 228 AVAALKNT 235 AA++ T Sbjct: 78 CQAAVRET 85 >2H8H-A nrPDB Length = 535 Score = 33.5 bits (75), Expect = 0.30, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 9/56 (16%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 AL+DY+ + LSF+ G+ L +++ + +WW A HS S T G+IPS Sbjct: 90 ALYDYESRTETD-----LSFKKGERLQIVNNTEGDWWLA---HSLS-TGQTGYIPS 136 >6F3F-A nrPDB Length = 455 Score = 33.5 bits (75), Expect = 0.36, Method: Compositional matrix adjust. Identities = 20/56 (35%), Positives = 31/56 (55%), Gaps = 9/56 (16%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 AL+DY+ + LSF+ G+ L +++ + +WW A HS S T G+IPS Sbjct: 10 ALYDYESRTETD-----LSFKKGERLQIVNNTEGDWWLA---HSLS-TGQTGYIPS 56 >3SOE-A nrPDB Length = 113 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 29/92 (31%), Positives = 43/92 (46%), Gaps = 13/92 (14%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 I L +G G GF+IA D P+ K+I Q L+ D I + +V Sbjct: 16 IPLIKGPKGFGFAIA---------DSPTGQKVKMILDSQWCQG--LQKGDIIKEIYHQNV 64 Query: 126 REVTHSAAVEALKE--AGSIVRLYVMRRKPPA 155 + +TH VE LK+ G+ V L ++R PP+ Sbjct: 65 QNLTHLQVVEVLKQFPVGADVPLLILRGGPPS 96 Score = 32.7 bits (73), Expect = 0.62, Method: Composition-based stats. Identities = 24/76 (31%), Positives = 36/76 (47%), Gaps = 11/76 (14%) Query: 158 VMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS 217 ++ I LIKGPKG GF+IA Q + I ++ +G LQ GD I + Sbjct: 13 LVTIPLIKGPKGFGFAIADSPTGQKV---KMILDSQWCQG--------LQKGDIIKEIYH 61 Query: 218 VGLEDVMHEDAVAALK 233 ++++ H V LK Sbjct: 62 QNVQNLTHLQVVEVLK 77 >5GJW-B nrPDB Length = 106 Score = 33.5 bits (75), Expect = 0.38, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 25/45 (55%), Gaps = 3/45 (6%) Query: 451 ALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVE 495 A++F D LH+ + + +WW R V E +GFIPS +++ Sbjct: 57 AITFEPKDFLHIKEKYNNDWWIGRLVKEGCE---VGFIPSPVKLD 98 >4D25-A nrPDB Length = 434 Score = 32.7 bits (73), Expect = 0.59, Method: Compositional matrix adjust. Identities = 27/87 (31%), Positives = 39/87 (44%), Gaps = 5/87 (5%) Query: 574 EIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQ----GKHCILD 629 E DG+ V K D A E S ++G +Q RE A Q GKHCIL Sbjct: 298 ENDGKRI-LVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILV 356 Query: 630 VSANAVRRLQAAHLHPIAIFIRPRSLE 656 +A A R L ++ + + P+S++ Sbjct: 357 ATAVAARGLDIKNVDIVVNYDLPKSID 383 >3BPU-A nrPDB Length = 88 Score = 32.3 bits (72), Expect = 0.71, Method: Composition-based stats. Identities = 21/76 (27%), Positives = 38/76 (50%), Gaps = 9/76 (11%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +++ + ++KGP G GF+IA PG V +I++ + + L+ GD I+ VN Sbjct: 3 ELITVHIVKGPMGFGFTIADS------PGGGGQRVKQIVD---SPRSRGLKEGDLIVEVN 53 Query: 217 SVGLEDVMHEDAVAAL 232 ++ + H V L Sbjct: 54 KKNVQALTHNQVVDML 69 Score = 32.0 bits (71), Expect = 1.1, Method: Composition-based stats. Identities = 30/98 (30%), Positives = 45/98 (45%), Gaps = 21/98 (21%) Query: 61 MEYEEITLERGNSGLGFSIA-----GGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVND 115 ME + + +G G GF+IA GG I D P + L+ D Sbjct: 2 MELITVHIVKGPMGFGFTIADSPGGGGQRVKQIVDSP--------------RSRGLKEGD 47 Query: 116 SILFVNEVDVREVTHSAAVEALKEA--GSIVRLYVMRR 151 I+ VN+ +V+ +TH+ V+ L E+ GS V L V R+ Sbjct: 48 LIVEVNKKNVQALTHNQVVDMLVESPKGSEVTLLVQRQ 85 Score = 29.6 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 39/82 (47%), Gaps = 7/82 (8%) Query: 314 IVIH--RGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNAS 371 I +H +G G GF I G G + I+ + S L++GD I+ VN +++ + Sbjct: 5 ITVHIVKGPMGFGFTIADSPGGGGQRVKQIV---DSPRSRGLKEGDLIVEVNKKNVQALT 61 Query: 372 HEQAAIALKNA--GQTVTIIAQ 391 H Q L + G VT++ Q Sbjct: 62 HNQVVDMLVESPKGSEVTLLVQ 83 >5MV8-B nrPDB Length = 130 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 22/74 (29%), Positives = 38/74 (51%), Gaps = 4/74 (5%) Query: 164 IKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDV 223 IK L ++ GGV + + V+ + E GAA + G + GD+I+A+N + D Sbjct: 36 IKKEGSLDLALEGGVDSPI----GKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDY 91 Query: 224 MHEDAVAALKNTYD 237 +A AAL+ ++ Sbjct: 92 TLAEADAALQKAWN 105 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 19/67 (28%), Positives = 37/67 (55%), Gaps = 5/67 (7%) Query: 336 IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA----GQTV-TIIA 390 + +S + G A+ G + KGD+I+++NG + + + +A AL+ A G + ++A Sbjct: 57 VVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYTLAEADAALQKAWNQGGDWIDLVVA 116 Query: 391 QYKPEEY 397 P+EY Sbjct: 117 VCPPKEY 123 >2X3W-D nrPDB Length = 60 Score = 31.6 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 5/50 (10%) Query: 429 RGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHS 478 +G +RAL+DYD G LSF+ GD L + DE+ W R+ S Sbjct: 2 KGVRVRALYDYD-----GQEQDELSFKAGDELTKLGEEDEQGWCRGRLDS 46 >4MT6-A nrPDB Length = 456 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 10/23 (43%), Positives = 19/23 (82%) Query: 449 SQALSFRFGDVLHVIDAGDEEWW 471 ++ L+F+ GDV+ V+DA +++WW Sbjct: 31 NRELAFKAGDVIKVLDASNKDWW 53 >4N78-F nrPDB Length = 514 Score = 30.8 bits (68), Expect = 2.2, Method: Compositional matrix adjust. Identities = 13/40 (32%), Positives = 24/40 (60%), Gaps = 5/40 (12%) Query: 433 IRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQ 472 + A++DY K K+ LSF+ G +++VI D+ W++ Sbjct: 457 VVAIYDYTKDKE-----DELSFQEGAIIYVIKKNDDGWYE 491 >2EAQ-A nrPDB Length = 90 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Query: 320 STGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 S GF I D GIF++ + AG PA+ S +L+ D+I+++N ++ A+ Sbjct: 16 SLDFGFTI--KWDIPGIFVASVEAGSPAEFS-QLQVDDEIIAINNTKFSYNDSKEWEEAM 72 Query: 380 KNAGQT 385 A +T Sbjct: 73 AKAQET 78 >2KJP-A nrPDB Length = 91 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 31/54 (57%), Gaps = 2/54 (3%) Query: 335 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTI 388 GI+ S ++ PA G++ GD+I+S +G + ++A I+ K AG VT+ Sbjct: 2 GIYASSVVENMPA--KGKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTL 53 >2NUP-C nrPDB Length = 196 Score = 30.8 bits (68), Expect = 2.4, Method: Compositional matrix adjust. Identities = 28/94 (29%), Positives = 45/94 (47%), Gaps = 10/94 (10%) Query: 549 DDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHL 608 +DL SEF ++ G VP +RP E D F+ +K+ D +A + + G N+ L Sbjct: 90 EDLHSEFDEQHGKKVPTVSRPYSFIEFDT----FIQKTKKLYIDSRARRNL--GSINTEL 143 Query: 609 YGTS---VQSVREVAEQGKHC-ILDVSANAVRRL 638 V ++ EV ++G+ LD AN + L Sbjct: 144 QDVQRIMVANIEEVLQRGEALSALDSKANNLSSL 177 >2QKW-B nrPDB Length = 321 Score = 30.4 bits (67), Expect = 2.6, Method: Compositional matrix adjust. Identities = 34/118 (28%), Positives = 52/118 (44%), Gaps = 22/118 (18%) Query: 582 FVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAA 641 F R +M I +K++E G HLYG+ + ++ EQ L++ A R L Sbjct: 103 FCDERNEM---ILIYKYMENGNLKRHLYGSDLPTMSMSWEQR----LEICIGAARGLH-- 153 Query: 642 HLHPIAIFIRPRSLENVLEINKRITEEQARKAFD-----RATKLEQEFTECFSAIVEG 694 +LH AI R +V IN + E K D + T+L+Q S +V+G Sbjct: 154 YLHTRAIIHR-----DVKSINILLDENFVPKITDFGISKKGTELDQTH---LSTVVKG 203 >1K4U-S nrPDB Length = 62 Score = 30.4 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 15/46 (32%), Positives = 26/46 (56%), Gaps = 5/46 (10%) Query: 428 KRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 K+G + ALF Y+ T+ + L F+ GD++ V+ +EEW + Sbjct: 3 KKGSQVEALFSYEATQ-----PEDLEFQEGDIILVLSKVNEEWLEG 43 >5T69-A nrPDB Length = 367 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 14/41 (34%), Positives = 27/41 (65%), Gaps = 1/41 (2%) Query: 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 +GI + +L G PA+ +G +R+GD I++V+G + + + Q Sbjct: 291 DGILVMRVLPGTPAERAG-IRRGDVIVAVDGTPISDGARLQ 330 >3GF9-A nrPDB Length = 295 Score = 30.4 bits (67), Expect = 3.1, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 24/44 (54%), Gaps = 5/44 (11%) Query: 429 RGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQ 472 +G + A++DY + LSF G +++V++ D +WWQ Sbjct: 17 QGCQVIAMYDYAANNE-----DELSFSKGQLINVMNKDDPDWWQ 55 >4BNE-A nrPDB Length = 457 Score = 30.0 bits (66), Expect = 3.6, Method: Compositional matrix adjust. Identities = 34/151 (22%), Positives = 63/151 (41%), Gaps = 24/151 (15%) Query: 347 ADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHD 406 ADL+ L + ++ + +GV L + ++ N +V+ Y + ++ D Sbjct: 317 ADLNRTLSRREKKKASDGVTLTGINQTGDQVSQPNKHSSVS--------SYEKNQSYPTD 368 Query: 407 LREQLMNSSLGSGTASLRSNP-------KRGFYIRALFDYDKTKDCGFLSQALSFRFGDV 459 ++ N+ S A +NP +RAL+DY+ G LSF+ GD Sbjct: 369 WSDEESNNPFSSTDAKGDTNPFDEDTSPVMEVRVRALYDYE-----GQEQDELSFKAGDE 423 Query: 460 LHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 L ++ DE+ W R+ + +G P+ Sbjct: 424 LTKMENEDEQGWCKGRL----DNGQVGLYPA 450 >1R6J-A nrPDB Length = 82 Score = 30.0 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 25/80 (31%), Positives = 39/80 (48%), Gaps = 8/80 (10%) Query: 310 EPRRIVIHRGSTG-LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 +PR I +H+ STG +GF G+ I+ I+ A +G L + + I +NG ++ Sbjct: 4 DPRTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVI 56 Query: 369 NASHEQAAIALKNAGQTVTI 388 Q A L +G VTI Sbjct: 57 GLKDSQIADILSTSGTVVTI 76 >5KZT-A nrPDB Length = 536 Score = 29.3 bits (64), Expect = 5.7, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 36/78 (46%), Gaps = 5/78 (6%) Query: 78 SIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSIL-FVNEVDVRE-VTHSAAVE 135 +IAG + P I DD +++ K+ + + ND + + VD T+S + Sbjct: 59 AIAGAAEEPKISDDKTVYTIKLREDAKWSNGDPVTANDYVYSWRRAVDPNTAATYSYLFD 118 Query: 136 ALKEAGSIVRLYVMRRKP 153 A+K G IV ++KP Sbjct: 119 AIKNGGDIV---AGKKKP 133 >3CYY-A nrPDB Length = 92 Score = 29.3 bits (64), Expect = 5.8, Method: Composition-based stats. Identities = 17/63 (26%), Positives = 32/63 (50%) Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSN 248 I+V +I + A +DG +Q GD +L +N E++ DA ++ + + + V + Sbjct: 25 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 84 Query: 249 AYL 251 A L Sbjct: 85 ATL 87 >5WQL-C nrPDB Length = 682 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 19/62 (30%), Positives = 31/62 (50%), Gaps = 5/62 (8%) Query: 177 GVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG--LEDVMH---EDAVAA 231 G+G D+ + ++ GG A K + +GDKI+ V G + DV+ +D VA Sbjct: 247 GIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVAL 306 Query: 232 LK 233 +K Sbjct: 307 IK 308 >3LA8-A nrPDB Length = 303 Score = 29.3 bits (64), Expect = 6.3, Method: Compositional matrix adjust. Identities = 18/82 (21%), Positives = 35/82 (42%), Gaps = 5/82 (6%) Query: 247 SNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEED 306 SNAY +D ++ + + ++ Y+G P+ TP R + + D +G Sbjct: 189 SNAYTADY---REVAHQVADKIGIKLDEGVYIGVSGPSYETPAEIRAFKTLGADAVGMST 245 Query: 307 IPREPRRIVIHRGSTGLGFNIV 328 +P + +H G LG + + Sbjct: 246 VPE--VIVAVHSGLKVLGISAI 265 >4Q4L-A nrPDB Length = 485 Score = 29.3 bits (64), Expect = 6.9, Method: Compositional matrix adjust. Identities = 19/70 (27%), Positives = 33/70 (47%), Gaps = 2/70 (2%) Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSN 248 IY I+EG + + Q+GD ++ +G D + V +KNT + + + V KP+ Sbjct: 52 IYDALILEGSELTLEVQQQLGDGVVRTICLGASDGLRRGVV--VKNTGNPISVPVGKPTL 109 Query: 249 AYLSDSYAPP 258 + D P Sbjct: 110 GRIMDVLGRP 119 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2XKX-A nrPDB 1042 0.0 3TSW-A nrPDB 350 1e-96 3SHW-A nrPDB 337 8e-93 4WSI-A nrPDB 328 5e-90 3LH5-A nrPDB 252 3e-67 4DEX-A nrPDB 237 1e-62 4ZW2-A nrPDB 234 9e-62 3KFV-A nrPDB 222 5e-58 1VYT-A nrPDB 217 2e-56 1LVG-A nrPDB 195 5e-50 4F4J-A nrPDB 189 4e-48 2QOR-A nrPDB 181 1e-45 1Z6G-A nrPDB 179 3e-45 2J41-A nrPDB 176 2e-44 2QT5-A nrPDB 170 3e-42 3LNC-A nrPDB 169 4e-42 6MFU-A nrPDB 165 7e-41 2F3T-A nrPDB 165 1e-40 3TAU-A nrPDB 155 5e-38 1P1D-A nrPDB 151 8e-37 3TR0-A nrPDB 151 1e-36 1U3B-A nrPDB 140 2e-33 1S4Q-A nrPDB 140 2e-33 3SUZ-A nrPDB 136 2e-32 3K1R-A nrPDB 110 2e-24 1WFV-A nrPDB 109 6e-24 2R4H-A nrPDB 107 2e-23 2JIL-A nrPDB 106 3e-23 5ZDS-A nrPDB 101 2e-21 3TSV-A nrPDB 100 3e-21 3EGH-C nrPDB 99 7e-21 5ZYS-A nrPDB 98 1e-20 4OEP-A nrPDB 98 1e-20 1UEQ-A nrPDB 97 3e-20 1X6D-A nrPDB 95 8e-20 1UEZ-A nrPDB 94 3e-19 1MFG-A nrPDB 93 3e-19 2QBW-A nrPDB 92 8e-19 3CH8-A nrPDB 92 1e-18 3SHU-A nrPDB 91 1e-18 4Q2Q-A nrPDB 91 2e-18 2Q9V-A nrPDB 90 5e-18 1UEP-A nrPDB 90 5e-18 2LOB-A nrPDB 89 6e-18 2DC2-A nrPDB 89 7e-18 4JOF-A nrPDB 89 7e-18 2KBS-A nrPDB 88 1e-17 2L4S-A nrPDB 87 2e-17 2VZ5-A nrPDB 86 4e-17 1X5N-A nrPDB 86 6e-17 3CBX-A nrPDB 84 2e-16 1N7E-A nrPDB 83 5e-16 5N7D-A nrPDB 81 2e-15 3FY5-A nrPDB 79 6e-15 2MX6-A nrPDB 78 1e-14 5G1D-A nrPDB 77 2e-14 5A2P-A nrPDB 77 3e-14 1UEW-A nrPDB 76 4e-14 4QL6-A nrPDB 75 1e-13 3QDO-A nrPDB 72 7e-13 1UJD-A nrPDB 71 2e-12 1GRI-A nrPDB 67 2e-11 1NF3-C nrPDB 62 1e-09 1GCQ-A nrPDB 61 1e-09 Sequences not found previously or not previously below threshold: 1VYV-A nrPDB 212 4e-55 1T0H-B nrPDB 152 5e-37 5GJV-C nrPDB 148 7e-36 1T0J-A nrPDB 87 2e-17 1V5Q-A nrPDB 83 4e-16 5GJW-B nrPDB 81 2e-15 1P1E-A nrPDB 81 2e-15 1UF1-A nrPDB 75 8e-14 1U37-A nrPDB 73 4e-13 1X5R-A nrPDB 73 4e-13 1U39-A nrPDB 71 1e-12 1Y7N-A nrPDB 70 3e-12 2LC7-A nrPDB 65 9e-11 1RY4-A nrPDB 65 1e-10 1UFX-A nrPDB 64 2e-10 4UU6-A nrPDB 64 3e-10 2DLS-A nrPDB 64 3e-10 1VA8-A nrPDB 63 5e-10 5E6P-B nrPDB 62 8e-10 2YT8-A nrPDB 62 8e-10 2YT7-A nrPDB 61 1e-09 2EDP-A nrPDB 59 5e-09 2V90-A nrPDB 59 5e-09 1M5Z-A nrPDB 59 5e-09 2PKT-A nrPDB 57 3e-08 1UJV-A nrPDB 56 5e-08 3PV2-A nrPDB 56 7e-08 1ZUB-A nrPDB 56 7e-08 3BPU-A nrPDB 55 1e-07 1V62-A nrPDB 54 2e-07 1WFG-A nrPDB 53 3e-07 1V6B-A nrPDB 53 4e-07 4A8B-A nrPDB 53 5e-07 3CYY-A nrPDB 53 6e-07 4YNN-A nrPDB 52 1e-06 2RCZ-A nrPDB 51 2e-06 5MV8-B nrPDB 50 3e-06 3PV4-A nrPDB 50 4e-06 4C2G-A nrPDB 50 4e-06 1R6J-A nrPDB 50 5e-06 4YO1-A nrPDB 49 6e-06 3SOE-A nrPDB 49 9e-06 5Y2D-A nrPDB 49 1e-05 1FC9-A nrPDB 48 2e-05 2EYZ-A nrPDB 47 2e-05 2LQW-A nrPDB 46 8e-05 2EAQ-A nrPDB 45 1e-04 2KL1-A nrPDB 45 1e-04 5JD8-A nrPDB 43 6e-04 5T69-A nrPDB 42 8e-04 5WQL-C nrPDB 42 9e-04 3EHQ-A nrPDB 41 0.001 2R98-A nrPDB 41 0.002 3GCO-A nrPDB 40 0.004 3MH6-A nrPDB 40 0.004 2D8I-A nrPDB 40 0.004 5Y28-A nrPDB 39 0.005 2KJP-A nrPDB 39 0.006 6F3F-A nrPDB 39 0.009 4RI0-A nrPDB 39 0.010 3JV3-A nrPDB 39 0.010 2H8H-A nrPDB 38 0.019 3NUM-A nrPDB 38 0.019 2PZ1-A nrPDB 37 0.026 4NXP-A nrPDB 37 0.029 4XI2-A nrPDB 36 0.045 3GF9-A nrPDB 36 0.045 2KJK-A nrPDB 36 0.053 3AGK-A nrPDB 36 0.063 5M3O-A nrPDB 35 0.098 3I1E-A nrPDB 35 0.11 4O06-A nrPDB 35 0.12 5O2P-A nrPDB 34 0.15 1GBQ-A nrPDB 34 0.19 4MT6-A nrPDB 34 0.19 1YWO-A nrPDB 34 0.22 3QO6-A nrPDB 34 0.23 3STJ-A nrPDB 34 0.25 4D25-A nrPDB 34 0.28 3K50-A nrPDB 34 0.31 4BNE-A nrPDB 34 0.33 1OV3-A nrPDB 33 0.39 3HAJ-A nrPDB 33 0.46 3QWY-A nrPDB 33 0.63 5O2M-A nrPDB 33 0.70 1K4U-S nrPDB 32 0.77 1UEC-A nrPDB 32 0.79 1X69-A nrPDB 32 0.80 5O2Q-A nrPDB 32 1.1 2YUP-A nrPDB 32 1.2 2HSP-A nrPDB 31 2.0 3J1E-A nrPDB 31 2.1 1WI7-A nrPDB 31 2.3 5XHZ-A nrPDB 31 2.3 2O2O-A nrPDB 31 2.3 1UE9-A nrPDB 30 3.9 4XCG-B nrPDB 30 4.4 2ED0-A nrPDB 29 5.9 1MKM-A nrPDB 29 8.1 >2XKX-A nrPDB Length = 721 Score = 1042 bits (2694), Expect = 0.0, Method: Composition-based stats. Identities = 718/724 (99%), Positives = 720/724 (99%), Gaps = 3/724 (0%) Query: 1 MDCLCIVTTKKYRYQDEDTPPLEHSPAHLPNQANSPPVIVNTDTLEAPGYELQVNGTEGE 60 MDCLCIVT KKYRYQDEDTPPL+HSPAHLPNQANSPPVIVNTDTLEAPGY VNGTEGE Sbjct: 1 MDCLCIVTAKKYRYQDEDTPPLKHSPAHLPNQANSPPVIVNTDTLEAPGY---VNGTEGE 57 Query: 61 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV Sbjct: 58 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 117 Query: 121 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN 180 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN Sbjct: 118 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGN 177 Query: 181 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY 240 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY Sbjct: 178 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVY 237 Query: 241 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 300 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD Sbjct: 238 LKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKD 297 Query: 301 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL 360 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL Sbjct: 298 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQIL 357 Query: 361 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT 420 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT Sbjct: 358 SVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT 417 Query: 421 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDS 480 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDS Sbjct: 418 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDS 477 Query: 481 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL 540 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL Sbjct: 478 ETDDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIIL 537 Query: 541 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIE 600 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI+AHKFIE Sbjct: 538 GPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIRAHKFIE 597 Query: 601 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE 660 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE Sbjct: 598 AGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLE 657 Query: 661 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 720 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA Sbjct: 658 INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVPA 717 Query: 721 RERL 724 RERL Sbjct: 718 RERL 721 >3TSW-A nrPDB Length = 391 Score = 350 bits (898), Expect = 1e-96, Method: Composition-based stats. Identities = 123/449 (27%), Positives = 189/449 (42%), Gaps = 94/449 (20%) Query: 303 GEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSV 362 G I R ++V R +G + GG D GIF++ +L PA G L +GDQIL V Sbjct: 1 GSHMILRPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRV 58 Query: 363 NGVDLRNASHEQAAIALKN--AGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGT 420 N VD N E+A + L + G+ VTI+AQ K + Y R ++ S +G Sbjct: 59 NNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRR-----------IVESDVGDS- 106 Query: 421 ASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA---GDEEWWQARRVH 477 FYIR F+Y+K G LSF G+V V+D G W A R+ Sbjct: 107 ----------FYIRTHFEYEKESPYG-----LSFNKGEVFRVVDTLYNGKLGSWLAIRIG 151 Query: 478 SDSETDDIGFIPSKRRVE----------------RREWSRLKAKDWGSSSGSQGRED--- 518 + + + G IP+K R E R ++ R + + + RED Sbjct: 152 KNHKEVERGIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSA 211 Query: 519 -----SVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREY 573 +YE V E + RP+ I GP D A + L E PD Y Sbjct: 212 QPVQTKFPAYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDI--------------Y 257 Query: 574 EIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSAN 633 +I + + ++ I+ H +++++ +Q KH +LDV+ N Sbjct: 258 QIAKSEPRDAGTDQRSSGIIRLH------------------TIKQIIDQDKHALLDVTPN 299 Query: 634 AVRRLQAAHLHPIAIFIRPRSLENVLEINKRITEE---QARKAFDRATKLEQEFTECFSA 690 AV RL A +PI +F+ P S + V + R+ E ARK ++R+ KL + F+ Sbjct: 300 AVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTT 359 Query: 691 IVEGDSFEE-IYHKVKRVIEDLSGPYIWV 718 + +S + Y +K I+ +WV Sbjct: 360 TINLNSMNDGWYGALKEAIQQQQNQLVWV 388 Score = 66.4 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 12/96 (12%) Query: 159 MEIKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN Sbjct: 8 PSMKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVN 59 Query: 217 SVGLEDVMHEDAVAALKN--TYDVVYLKVAKPSNAY 250 +V +++ E+AV L + + V + K + Y Sbjct: 60 NVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVY 95 Score = 57.2 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 R +G +AGG D IF+ ++ AA++G L D IL VN VD + Sbjct: 16 RKGDSVGLRLAGGND-------VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNII 67 Query: 130 HSAAVEALKE--AGSIVRLYVMRRKPPAEKVMEIKL 163 AV L + G V + ++K +++E + Sbjct: 68 REEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDV 103 >3SHW-A nrPDB Length = 468 Score = 337 bits (865), Expect = 8e-93, Method: Composition-based stats. Identities = 120/441 (27%), Positives = 186/441 (42%), Gaps = 94/441 (21%) Query: 311 PRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 ++V R +G + GG D GIF++ +L PA G L +GDQIL VN VD N Sbjct: 1 SMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNI 58 Query: 371 SHEQAAIALKN--AGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPK 428 E+A + L + G+ VTI+AQ K + Y R ++ S +G Sbjct: 59 IREEAVLFLLDLPKGEEVTILAQKKKDVYRR-----------IVESDVGDS--------- 98 Query: 429 RGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA---GDEEWWQARRVHSDSETDDI 485 FYIR F+Y+K G LSF G+V V+D G W A R+ + + + Sbjct: 99 --FYIRTHFEYEKESPYG-----LSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVER 151 Query: 486 GFIPSKRRVE----------------RREWSRLKAKDWGSSSGSQGRED--------SVL 521 G IP+K R E R ++ R + + + RED Sbjct: 152 GIIPNKNRAEQLASVQYTLPKTAGGDRADFWRFRGLRSSKRNLRKSREDLSAQPVQTKFP 211 Query: 522 SYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYH 581 +YE V E + RP+ I GP D A + L E PD Y+I + Sbjct: 212 AYERVVLREAGFLRPVTIFGPIADVAREKLAREEPDI--------------YQIAKSEPR 257 Query: 582 FVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAA 641 + ++ I+ H +++++ +Q KH +LDV+ NAV RL A Sbjct: 258 DAGTDQRSSGIIRLH------------------TIKQIIDQDKHALLDVTPNAVDRLNYA 299 Query: 642 HLHPIAIFIRPRSLENVLEINKRITEE---QARKAFDRATKLEQEFTECFSAIVEGDSFE 698 +PI +F+ P S + V + R+ E ARK ++R+ KL + F+ + +S Sbjct: 300 QWYPIVVFLNPDSKQGVKTMRMRLCPESRKSARKLYERSHKLRKNNHHLFTTTINLNSMN 359 Query: 699 E-IYHKVKRVIEDLSGPYIWV 718 + Y +K I+ +WV Sbjct: 360 DGWYGALKEAIQQQQNQLVWV 380 Score = 64.9 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 12/95 (12%) Query: 160 EIKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS 217 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+ Sbjct: 1 SMKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNN 52 Query: 218 VGLEDVMHEDAVAALKN--TYDVVYLKVAKPSNAY 250 V +++ E+AV L + + V + K + Y Sbjct: 53 VDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVY 87 Score = 56.8 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 R +G +AGG D IF+ ++ AA++G L D IL VN VD + Sbjct: 8 RKGDSVGLRLAGGND-------VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNII 59 Query: 130 HSAAVEALKE--AGSIVRLYVMRRKPPAEKVMEIKL 163 AV L + G V + ++K +++E + Sbjct: 60 REEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDV 95 >4WSI-A nrPDB Length = 394 Score = 328 bits (841), Expect = 5e-90, Method: Composition-based stats. Identities = 125/425 (29%), Positives = 195/425 (45%), Gaps = 74/425 (17%) Query: 312 RRIVIHRGST-GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 + + I + LG + + + + IS I+ GG A+ SG L +GD++L +NG+++R Sbjct: 24 KIVRIEKARDIPLGATVR--NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 81 Query: 371 SHEQAAIALKNAGQTVTIIA----QYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSN 426 + L + T+T + Q KP E IH Sbjct: 82 DVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAK--ETVIH--------------------- 118 Query: 427 PKRGFYIRALFDYDKTKD--CGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDD 484 ++A FDYD + D LSF+ GD+LHVI D WWQA R + Sbjct: 119 ------VKAHFDYDPSDDPYVPCRELGLSFQKGDILHVISQEDPNWWQAYREGDEDNQPL 172 Query: 485 IGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVT--QMEVHYARPIIILGP 542 G +P K + +L+YE ++ + RPII++GP Sbjct: 173 AGLVPGK--------------------------EEILTYEEMSLYHQPANRKRPIILIGP 206 Query: 543 TKDR---ANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFI 599 L+++ D+F S VPHTTR +R+ E+ GRDYHFV SR+ E DI A KFI Sbjct: 207 QNCGQNELRQRLMNKEKDRFASAVPHTTRSRRDQEVAGRDYHFV-SRQAFEADIAAGKFI 265 Query: 600 EAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVL 659 E G++ +LYGTS+ SVR+V GK C+L + +++ L+ + L P IFI P S E + Sbjct: 266 EHGEFEKNLYGTSIDSVRQVINSGKICLLSLRTQSLKTLRNSDLKPYIIFIAPPSQERLR 325 Query: 660 EI----NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPY 715 + K E+ R+ ++ ++EQ F + ++ Y ++ R+I L Sbjct: 326 ALLAKEGKNPKPEELREIIEKTREMEQNNGHYFDTAIVNSDLDKAYQELLRLINKLDTEP 385 Query: 716 IWVPA 720 WVP+ Sbjct: 386 QWVPS 390 Score = 53.7 bits (127), Expect = 3e-07, Method: Composition-based stats. Identities = 18/69 (26%), Positives = 34/69 (49%), Gaps = 3/69 (4%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 S+ I++I+ GGAA + G L D +L +N +++R + + L + + ++ Sbjct: 45 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 104 Query: 152 ---KPPAEK 157 KPP K Sbjct: 105 QQIKPPPAK 113 Score = 53.3 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 42/102 (41%), Gaps = 9/102 (8%) Query: 156 EKVMEIKLIKGPK-GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 E V +++ K LG ++ + S+ +++I++GGAA K G L GD++L Sbjct: 21 ETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAAEKSGLLHEGDEVLE 72 Query: 215 VNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYA 256 +N + + + L + + + + + Sbjct: 73 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSQQIKPPPAKE 114 >3LH5-A nrPDB Length = 251 Score = 252 bits (644), Expect = 3e-67, Method: Composition-based stats. Identities = 78/296 (26%), Positives = 125/296 (42%), Gaps = 57/296 (19%) Query: 430 GFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDA---GDEEWWQARRVHSDSETDDIG 486 FYIR F+Y+K G LSF G+V V+D G W A R+ + + + G Sbjct: 3 SFYIRTHFEYEKESPYG-----LSFNKGEVFRVVDTLYNGKLGSWLAIRIGKNHKEVERG 57 Query: 487 FIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDR 546 IP+K R E+ + Q + +YE V E + RP+ I GP D Sbjct: 58 IIPNKNRAEQL-------------ASVQYVQTKFPAYERVVLREAGFLRPVTIFGPIADV 104 Query: 547 ANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNS 606 A + L E PD Y+I + + ++ I+ H Sbjct: 105 AREKLAREEPDI--------------YQIAKSEPRDAGTDQRSSGIIRLH---------- 140 Query: 607 HLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRIT 666 +++++ +Q KH +LDV+ NAV RL A +PI +F+ P S + V + R+ Sbjct: 141 --------TIKQIIDQDKHALLDVTPNAVDRLNYAQWYPIVVFLNPDSKQGVKTMRMRLC 192 Query: 667 EE---QARKAFDRATKLEQEFTECFSAIVEGDSFEE-IYHKVKRVIEDLSGPYIWV 718 E ARK ++R+ KL + F+ + +S + Y +K I+ +WV Sbjct: 193 PESRKSARKLYERSHKLRKNNHHLFTTTINLNSMNDGWYGALKEAIQQQQNQLVWV 248 >4DEX-A nrPDB Length = 339 Score = 237 bits (604), Expect = 1e-62, Method: Composition-based stats. Identities = 66/300 (22%), Positives = 114/300 (38%), Gaps = 38/300 (12%) Query: 430 GFYIRALFDYDKTK--DCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y D A+SF D LHV + + +WW R V E IGF Sbjct: 40 AFAVRTNVSYSAAHEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCE---IGF 96 Query: 488 IPSKRRVER-REWSRLKAKDWGSSS-----GSQGREDSVLSYETVTQMEVHYARPIIILG 541 IPS ++E R +AK++ S + + Y+ V M RP++++G Sbjct: 97 IPSPVKLENMRLQHEQRAKEFKLHSKEKRMPFFKKTEHTPPYDVVPSM-----RPVVLVG 151 Query: 542 PT------KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQA 595 P+ D L +F + TR + + R S+ Sbjct: 152 PSLKGYEVTDMMQKALFDFLKHRFEGRIS-ITRVTADISLAKRSVLNNPSK--------- 201 Query: 596 HKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDVS-ANAVRRLQAAHLHPIAIFIR- 651 H IE S L + ++ + E+A + +LD N +L L PI ++++ Sbjct: 202 HAIIERSNTRSSLAEVQSEIERIFELARTLQLVVLDADTINHPAQLSKTSLAPIVVYVKI 261 Query: 652 --PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 709 P+ L+ +++ + + A KL Q E F I++ + E+ + +E Sbjct: 262 SSPKVLQRLIKSRGKSQAKHLNVQMVAADKLAQCPPELFDVILDENQLEDACEHLADYLE 321 >4ZW2-A nrPDB Length = 333 Score = 234 bits (597), Expect = 9e-62, Method: Composition-based stats. Identities = 63/302 (20%), Positives = 114/302 (37%), Gaps = 40/302 (13%) Query: 430 GFYIRALFDYDKTK--DCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y+ + + A++F D LH+ + + +WW R V E +GF Sbjct: 39 AFAVRTNVGYNPSPGDEVPVQGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE---VGF 95 Query: 488 IPSKRRVER--------REWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIII 539 IPS +++ +RL + G + + V Y+ V M RPII+ Sbjct: 96 IPSPVKLDSLRLLQEQTLRQNRLSSSKHGKRIPFFKKTEHVPPYDVVPSM-----RPIIL 150 Query: 540 LGPT------KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI 593 +GP+ D L +F + TR + + R S+ Sbjct: 151 VGPSLKGYEVTDMMQKALFDFLKHRFDGRIS-ITRVTADISLAKRSVLNNPSK------- 202 Query: 594 QAHKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDVS-ANAVRRLQAAHLHPIAIFI 650 H IE S L + ++ + E+A + LD N +L L PI ++I Sbjct: 203 --HIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDADTINHPAQLSKTSLAPIIVYI 260 Query: 651 R---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRV 707 + P+ L+ +++ + + + KL Q E F I++ + E+ + Sbjct: 261 KITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEMFDIILDENQLEDACEHLAEY 320 Query: 708 IE 709 +E Sbjct: 321 LE 322 >3KFV-A nrPDB Length = 308 Score = 222 bits (565), Expect = 5e-58, Method: Composition-based stats. Identities = 79/337 (23%), Positives = 127/337 (37%), Gaps = 91/337 (27%) Query: 430 GFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEE---------WWQARRVHSDS 480 FYIR F+ + + G L F GDV HV+D W A R+ D Sbjct: 4 SFYIRTHFELEPSPPSG-----LGFTRGDVFHVLDTLHPGPGQSHARGGHWLAVRMGRDL 58 Query: 481 ETDDIGFIPSKRRVE------------------------RREWSRLKAKDWGSSSGSQG- 515 + G IP++ R E R E+ RL+ G+ +Q Sbjct: 59 REQERGIIPNQSRAEQLASLEAAQRAVGVGPGSSAGSNARAEFWRLRGLRRGAKKTTQRS 118 Query: 516 --------REDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKF--GSCVPH 565 R+ YE V E + RP++ILGP D A L +E PD+F V Sbjct: 119 REDLSALTRQGRYPPYERVVLREASFKRPVVILGPVADIAMQKLTAEMPDQFEIAETVSR 178 Query: 566 TTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKH 625 T P + ++D +VR +AE+ KH Sbjct: 179 TDSPSKIIKLD--------------------------------------TVRVIAEKDKH 200 Query: 626 CILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEINKRI---TEEQARKAFDRATKLEQ 682 +LDV+ +A+ RL +PI +F P S + + + + + R+ + +A KL + Sbjct: 201 ALLDVTPSAIERLNYVQYYPIVVFFIPESRPALKALRQWLAPASRRSTRRLYAQAQKLRK 260 Query: 683 EFTECFSAIVE-GDSFEEIYHKVKRVIEDLSGPYIWV 718 + F+A + + + Y ++K +I + IW Sbjct: 261 HSSHLFTATIPLNGTSDTWYQELKAIIREQQTRPIWT 297 >1VYT-A nrPDB Length = 351 Score = 217 bits (551), Expect = 2e-56, Method: Composition-based stats. Identities = 64/312 (20%), Positives = 113/312 (36%), Gaps = 50/312 (16%) Query: 430 GFYIRALFDYDKTKD--CGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y D C ++F D LH+ + +WW R V E DI F Sbjct: 46 AFAVRTNVSYCGVLDEECPVQGSGVNFEAKDFLHIKEKYSNDWWIGRLVK---EGGDIAF 102 Query: 488 IPSKRRVER-REWSRLKAKDWGSSSG-----------------SQGREDSVLSYETVTQM 529 IPS +R+E R KA+ G+ S Q + + V Y+ V M Sbjct: 103 IPSPQRLESIRLKQEQKARRSGNPSSLSDIGNRRSPPPSLAKQKQKQAEHVPPYDVVPSM 162 Query: 530 EVHYARPIIILGPT------KDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFV 583 RP++++GP+ D L +F + TR + + R Sbjct: 163 -----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRIS-ITRVTADLSLAKRSVLNN 216 Query: 584 SSREKMEKDIQAHKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDVS-ANAVRRLQA 640 + IE S + + ++ + E+A+ + +LD N +L Sbjct: 217 PGKR---------TIIERSSARSSIAEVQSEIERIFELAKSLQLVVLDADTINHPAQLAK 267 Query: 641 AHLHPIAIFIR---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSF 697 L PI +F++ P+ L+ ++ + + KL Q E F I++ + Sbjct: 268 TSLAPIIVFVKVSSPKVLQRLIRSRGKSQMKHLTVQMMAYDKLVQCPPESFDVILDENQL 327 Query: 698 EEIYHKVKRVIE 709 ++ + +E Sbjct: 328 DDACEHLAEYLE 339 >1VYV-A nrPDB Length = 359 Score = 212 bits (540), Expect = 4e-55, Method: Composition-based stats. Identities = 65/321 (20%), Positives = 113/321 (35%), Gaps = 59/321 (18%) Query: 430 GFYIRALFDYDKT--KDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F ++ Y +D S A+SF D LH+ + + +WW R V E IGF Sbjct: 45 AFAVKTNVSYCGALDEDVPVPSSAVSFDAKDFLHIKEKYNNDWWIGRLVKEGCE---IGF 101 Query: 488 IPSKRRVER-REWSRLKAKDW--------------------------GSSSGSQGREDSV 520 IPS R+E R K K + ++ Q + Sbjct: 102 IPSPLRLENIRIQQEQKRKRFHGGKSSGNSSSSLGEMVSGTFRATPTTTAKQKQKVTKHI 161 Query: 521 LSYETVTQMEVHYARPIIILGPT------KDRANDDLLSEFPDKFGSCVPHTTRPKREYE 574 Y+ V M RP++++GP+ D L +F + TR + Sbjct: 162 PPYDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFDGRIS-ITRVTADIS 215 Query: 575 IDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDVS- 631 + R S+ IE S L + ++ + E+A + +LD Sbjct: 216 LAKRSVLNNPSKR---------AIIERSNTKSSLAEVQSEIERIFELARSLQLVVLDADT 266 Query: 632 ANAVRRLQAAHLHPIAIFIR---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTECF 688 N +L L PI + ++ P+ L+ +++ + + A KL Q E F Sbjct: 267 INHPAQLIKTSLAPIIVHVKVSSPKVLQRLIKSRGKSQSKHLNVQLVAADKLAQCPPEMF 326 Query: 689 SAIVEGDSFEEIYHKVKRVIE 709 I++ + E+ + +E Sbjct: 327 DVILDENQLEDACEHLGEYLE 347 >1LVG-A nrPDB Length = 198 Score = 195 bits (495), Expect = 5e-50, Method: Composition-based stats. Identities = 64/184 (34%), Positives = 96/184 (52%), Gaps = 9/184 (4%) Query: 535 RPIIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEK 591 RP+++ GP K L E FG V HTTR R E DG+DY+FV +RE M++ Sbjct: 5 RPVVLSGPSGAGKSTLLKKLFQEHSSIFGFSVSHTTRNPRPGEEDGKDYYFV-TREMMQR 63 Query: 592 DIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIR 651 DI A FIE +++ +LYGTS ++VR V + C+LDV VR ++ L PI IF++ Sbjct: 64 DIAAGDFIEHAEFSGNLYGTSKEAVRAVQAMNRICVLDVDLQGVRSIKKTDLCPIYIFVQ 123 Query: 652 PRSLENV---LEINKRITEEQARKAFDRATKLEQEFTE--CFSAIVEGDSFEEIYHKVKR 706 P SL+ + L + TEE K A + E F ++ D ++ Y +K+ Sbjct: 124 PPSLDVLEQRLRLRNTETEESLAKRLAAARTDMESSKEPGLFDLVIINDDLDKAYATLKQ 183 Query: 707 VIED 710 + + Sbjct: 184 ALSE 187 >4F4J-A nrPDB Length = 202 Score = 189 bits (479), Expect = 4e-48, Method: Composition-based stats. Identities = 63/187 (33%), Positives = 102/187 (54%), Gaps = 9/187 (4%) Query: 530 EVHYARPIIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSR 586 + +RPI+I GP K L +E+PD FG VP TTR R E++G+DY+FVS Sbjct: 13 QGSMSRPIVISGPSGTGKSTLLKKLFAEYPDSFGFSVPSTTRTPRAGEVNGKDYNFVSVD 72 Query: 587 EKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQA-AHLHP 645 E + I+ ++FIE Q++ + YG++V SV++V++ GK CILD+ V+ ++A L+ Sbjct: 73 E-FKSMIKNNEFIEWAQFSGNYYGSTVASVKQVSKSGKTCILDIDMQGVKSVKAIPELNA 131 Query: 646 IAIFIRPRSLENVLEI---NKRITEEQARKAFDRAT-KLEQEFTECFSAIVEGDSFEEIY 701 +FI P S+E++ + TEE K A +L T ++ D ++ Y Sbjct: 132 RFLFIAPPSVEDLKKRLEGRGTETEESINKRLSAAQAELAYAETGAHDKVIVNDDLDKAY 191 Query: 702 HKVKRVI 708 ++K I Sbjct: 192 KELKDFI 198 >2QOR-A nrPDB Length = 204 Score = 181 bits (458), Expect = 1e-45, Method: Composition-based stats. Identities = 50/182 (27%), Positives = 92/182 (50%), Gaps = 10/182 (5%) Query: 536 PIIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKD 592 P+++ GP K +LSEFP +F + TTR KRE E +G DY+FV ++ E+ Sbjct: 14 PLVVCGPSGVGKGTLIKKVLSEFPSRFRFSISCTTRNKREKETNGVDYYFV-DKDDFERK 72 Query: 593 IQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAH--LHPIAIFI 650 ++ +F+E +Y ++ YGT +GK C+ +++ N V++L+ + I IF+ Sbjct: 73 LKEGQFLEFDKYANNFYGTLKSEYDLAVGEGKICLFEMNINGVKQLKESKHIQDGIYIFV 132 Query: 651 RPRSLENVLEINKRITEEQARKAFDRATKLEQEFTEC----FSAIVEGDSFEEIYHKVKR 706 +P S++ +L K E+ + R +L +E E F+ + D Y +++ Sbjct: 133 KPPSIDILLGRLKNRNTEKPEEINKRMQELTREMDEADKVGFNYFIVNDDLARTYAELRE 192 Query: 707 VI 708 + Sbjct: 193 YL 194 >1Z6G-A nrPDB Length = 218 Score = 179 bits (454), Expect = 3e-45, Method: Composition-based stats. Identities = 56/200 (28%), Positives = 92/200 (46%), Gaps = 13/200 (6%) Query: 526 VTQMEVHYARPIIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHF 582 V + ++ P++I GP K LL+EFP+ F V TTR KRE E +G DY+F Sbjct: 15 VPRGSMNNIYPLVICGPSGVGKGTLIKKLLNEFPNYFYFSVSCTTRKKREKEKEGVDYYF 74 Query: 583 VSSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAH 642 + + E ++ F+E Y ++ YGT + EQ K C+ +++ N V++L+ + Sbjct: 75 I-DKTIFEDKLKNEDFLEYDNYANNFYGTLKSEYDKAKEQNKICLFEMNINGVKQLKKST 133 Query: 643 L--HPIAIFIRPRSLENVLEINKRITEEQARKAFDRATKLEQEFTEC----FSAIVEGDS 696 + + IFI+P S + +L E + R +L E E F+ + D Sbjct: 134 HIKNALYIFIKPPSTDVLLSRLLTRNTENQEQIQKRMEQLNIELHEANLLNFNLSIINDD 193 Query: 697 FEEIYHKVKRVIEDLSGPYI 716 Y ++K L YI Sbjct: 194 LTLTYQQLK---NYLLNSYI 210 >2J41-A nrPDB Length = 207 Score = 176 bits (447), Expect = 2e-44, Method: Composition-based stats. Identities = 49/193 (25%), Positives = 90/193 (46%), Gaps = 8/193 (4%) Query: 537 IIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI 593 I++ GP K + + + + TTR RE E+DG DY F +R+ E I Sbjct: 9 IVLSGPSGVGKGTVRKRIFEDPSTSYKYSISMTTRQMREGEVDGVDYFF-KTRDAFEALI 67 Query: 594 QAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPR 653 + +FIE +Y + YGT VQ V++ ++G L++ ++++ + IF+ P Sbjct: 68 KDDQFIEYAEYVGNYYGTPVQYVKDTMDEGHDVFLEIEVEGAKQVRKKFPDALFIFLAPP 127 Query: 654 SLENVLEI---NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIED 710 SLE++ E ++E+ + + A K E E + +V D E ++++ ++E Sbjct: 128 SLEHLRERLVGRGTESDEKIQSRINEARK-EVEMMNLYDYVVVNDEVELAKNRIQCIVEA 186 Query: 711 LSGPYIWVPARER 723 V A+ R Sbjct: 187 EHLKRERVEAKYR 199 >2QT5-A nrPDB Length = 200 Score = 170 bits (429), Expect = 3e-42, Method: Composition-based stats. Identities = 56/239 (23%), Positives = 96/239 (40%), Gaps = 60/239 (25%) Query: 163 LIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 + K LG +++GG+ P V+ + +GG A + +L +GD I AVN + L Sbjct: 14 MKKEGTTLGLTVSGGIDKDGKP-----RVSNLRQGGIAARSDQLDVGDYIKAVNGINLAK 68 Query: 223 VMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDY 282 H++ ++ LKN + V L+V Y P ++ S + + Sbjct: 69 FRHDEIISLLKNVGERVVLEV----------EYELPPVSIQGSSVMFRTV---------- 108 Query: 283 PTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE-----GIF 337 + +H+ GF I GG + + Sbjct: 109 ------------------------------EVTLHKEGNTFGFVIRGGAHDDRNKSRPVV 138 Query: 338 ISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEE 396 I+ + GGPAD G ++ GD++LSV+G+ L +H +A LK GQ T++ +Y Sbjct: 139 ITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEYDVSV 197 Score = 162 bits (410), Expect = 5e-40, Method: Composition-based stats. Identities = 48/184 (26%), Positives = 85/184 (46%), Gaps = 14/184 (7%) Query: 68 LERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 +++ + LG +++GG D D ++ + GG AA+ +L V D I VN +++ + Sbjct: 14 MKKEGTTLGLTVSGGID-----KDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAK 68 Query: 128 VTHSAAVEALKEAGSIVRLYVMRRKPPAE--------KVMEIKLIKGPKGLGFSIAGGVG 179 H + LK G V L V PP + +E+ L K GF I GG Sbjct: 69 FRHDEIISLLKNVGERVVLEVEYELPPVSIQGSSVMFRTVEVTLHKEGNTFGFVIRGGA- 127 Query: 180 NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVV 239 + + +T + GG A ++G ++ GD++L+V+ + L H +A++ LK Sbjct: 128 HDDRNKSRPVVITCVRPGGPADREGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEA 187 Query: 240 YLKV 243 L + Sbjct: 188 TLLI 191 Score = 113 bits (282), Expect = 3e-25, Method: Composition-based stats. Identities = 30/104 (28%), Positives = 50/104 (48%), Gaps = 4/104 (3%) Query: 50 YEL---QVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAA 106 YEL + G+ E+TL + + GF I GG + P + IT + PGG A Sbjct: 91 YELPPVSIQGSSVMFRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRP-VVITCVRPGGPAD 149 Query: 107 QDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 ++G ++ D +L V+ + + TH+ A+ LK+ G L + Sbjct: 150 REGTIKPGDRLLSVDGIRLLGTTHAEAMSILKQCGQEATLLIEY 193 Score = 64.5 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 28/84 (33%), Positives = 44/84 (52%), Gaps = 1/84 (1%) Query: 316 IHRGSTGLGFNIVGGEDGEGI-FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + + T LG + GG D +G +S + GG A S +L GD I +VNG++L H++ Sbjct: 14 MKKEGTTLGLTVSGGIDKDGKPRVSNLRQGGIAARSDQLDVGDYIKAVNGINLAKFRHDE 73 Query: 375 AAIALKNAGQTVTIIAQYKPEEYS 398 LKN G+ V + +Y+ S Sbjct: 74 IISLLKNVGERVVLEVEYELPPVS 97 >3LNC-A nrPDB Length = 231 Score = 169 bits (428), Expect = 4e-42, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 76/176 (43%), Gaps = 4/176 (2%) Query: 540 LGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFI 599 G K + LL + + V TTR R+ E +G+DY+FV RE+ + + I Sbjct: 36 SGCGKTTVANKLLEKQKNNIVKSVSVTTRAARKGEKEGKDYYFV-DREEFLRLCSNGEII 94 Query: 600 EAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAV-RRLQAAHLHPIAIFIRPRSLENV 658 E + + YG +++ + ++G +L + + ++ H ++IFI P S+E + Sbjct: 95 EHAEVFGNFYGVPRKNLEDNVDKGVSTLLVIDWQGAFKFMEMMREHVVSIFIMPPSMEEL 154 Query: 659 LE--INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLS 712 +R + + +A + E E + ++ + EE ++ ++ Sbjct: 155 RRRLCGRRADDSEVVEARLKGAAFEISHCEAYDYVIVNEDIEETADRISNILRAEQ 210 >6MFU-A nrPDB Length = 225 Score = 165 bits (417), Expect = 7e-41, Method: Composition-based stats. Identities = 57/200 (28%), Positives = 89/200 (44%), Gaps = 16/200 (8%) Query: 527 TQMEVHYARPIIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFV 583 RP++I GP K L P+ FG V HTTR R E +GR+YHFV Sbjct: 12 PINPDVVNRPLVICGPSGTGKSTLLKTLFESQPNTFGFSVSHTTRKPRPGEENGREYHFV 71 Query: 584 SSREKMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHL 643 + E ME + +F+E ++ + YGT+ ++ A + CILD+ V +L+A Sbjct: 72 TKEEFMEG-VGKGEFLEWAEFGGNCYGTTFAAL--TALHPRRCILDIELQGVLQLKAKAP 128 Query: 644 ------HPIAIFIRPRSLENVL-EINKRITEEQA--RKAFDRA-TKLEQEFTECFSAIVE 693 P+ +F+ P S+ + ++ R TE A RK D A +L + V Sbjct: 129 LQTPPLEPVFLFLSPPSISQLKSRLSGRGTETDASIRKRLDAAKEELRYAKEGKYDVYVV 188 Query: 694 GDSFEEIYHKVKRVIEDLSG 713 D + K+++V G Sbjct: 189 NDDLKVAGEKLEKVAMGWEG 208 >2F3T-A nrPDB Length = 207 Score = 165 bits (416), Expect = 1e-40, Method: Composition-based stats. Identities = 44/174 (25%), Positives = 71/174 (40%), Gaps = 6/174 (3%) Query: 540 LGPTKDRANDDLLSEFPDK-FGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKF 598 G K LL P V HTTR R E+ G Y FV+ E ++ I F Sbjct: 13 SGAGKSSLIQALLKTQPLYDTQVSVSHTTRQPRPGEVHGEHYFFVNHDE-FKEMISRDAF 71 Query: 599 IEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENV 658 +E + + YGTS +++ +V G LD+ ++++ H +IFI P S + Sbjct: 72 LEHAEVFGNYYGTSREAIEQVLATGVDVFLDIDWQGAQQIRQKMPHARSIFILPPSKIEL 131 Query: 659 -LEINKRIT--EEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 709 + R EE K +A + E + ++ D F+ +K +I Sbjct: 132 DRRLRGRGQDSEEVIAKRMAQAVAEMSHYAE-YDYLIVNDDFDTALTDLKTIIR 184 >3TAU-A nrPDB Length = 208 Score = 155 bits (392), Expect = 5e-38, Method: Composition-based stats. Identities = 54/200 (27%), Positives = 84/200 (42%), Gaps = 26/200 (13%) Query: 537 IIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDI 593 I++ GP K + + + F + TTR RE E DG DY+F SRE E+ I Sbjct: 11 IVLSGPSGVGKGTVREAVFKDPETSFDYSISMTTRLPREGEQDGVDYYF-RSREVFEQAI 69 Query: 594 QAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPR 653 + K +E +Y + YGT ++ V E G L++ +++ A I IF+ P Sbjct: 70 KDGKMLEYAEYVGNYYGTPLEYVEEKLAAGVDIFLEIEVQGAMQVRKAMPEGIFIFLTPP 129 Query: 654 SLENVL-EINKRITE--EQARKAFDRATKLEQEFTECFSA----------------IVEG 694 L + I R TE E + + A K E E + IVE Sbjct: 130 DLSELKNRIIGRGTESMEVVEERMETAKK-EIEMMASYDYAVVNDVVANAVQKIKGIVET 188 Query: 695 DSF--EEIYHKVKRVIEDLS 712 + E + H+ K+++E L Sbjct: 189 EHLKTERVIHRYKKMLEGLQ 208 >1T0H-B nrPDB Length = 224 Score = 152 bits (384), Expect = 5e-37, Method: Composition-based stats. Identities = 39/214 (18%), Positives = 77/214 (35%), Gaps = 28/214 (13%) Query: 509 SSSGSQGREDSVLSYETVTQMEVHYARPIIILGPT------KDRANDDLLSEFPDKFGSC 562 + + Y+ V M RP++++GP+ D L +F Sbjct: 5 KRMPFFKKTEHTPPYDVVPSM-----RPVVLVGPSLKGYEVTDMMQKALFDFLKHRFEGR 59 Query: 563 VPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHL--YGTSVQSVREVA 620 + TR + + R S+ H IE S L + ++ + E+A Sbjct: 60 IS-ITRVTADISLAKRSVLNNPSK---------HAIIERSNTRSSLAEVQSEIERIFELA 109 Query: 621 EQGKHCILDVS-ANAVRRLQAAHLHPIAIFIR---PRSLENVLEINKRITEEQARKAFDR 676 + +LD N +L L PI ++++ P+ L+ +++ + + Sbjct: 110 RTLQLVVLDADTINHPAQLSKTSLAPIIVYVKISSPKVLQRLIKSRGKSQAKHLNVQMVA 169 Query: 677 ATKLEQEFT-ECFSAIVEGDSFEEIYHKVKRVIE 709 A KL Q E F I++ + E+ + +E Sbjct: 170 ADKLAQCPPQESFDVILDENQLEDACEHLADYLE 203 >1P1D-A nrPDB Length = 196 Score = 151 bits (382), Expect = 8e-37, Method: Composition-based stats. Identities = 48/183 (26%), Positives = 89/183 (48%), Gaps = 11/183 (6%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 +G G + G P + I+ I A + G L++ D ++ +N + + T Sbjct: 18 TGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEE 76 Query: 133 AVEALKEAGSIVRLYVMRRKPPAEKVMEIK---LIKGPKG----LGFSIAGGVGNQHIPG 185 A + L+++ ++ + AE V+ +K PK LG +I+ + PG Sbjct: 77 ANQLLRDSSITSKVTLEIEFDVAESVIPSSGTFHVKLPKKHSVELGITISSPSSRK--PG 134 Query: 186 DNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 D + ++ I +G AH+ G L++GDK+LA++++ L+ EDAV L+ D+V LK+ K Sbjct: 135 D-PLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDSCSMEDAVQILQQCEDLVKLKIRK 193 Query: 246 PSN 248 + Sbjct: 194 DED 196 Score = 88.4 bits (217), Expect = 1e-17, Method: Composition-based stats. Identities = 51/241 (21%), Positives = 89/241 (36%), Gaps = 50/241 (20%) Query: 156 EKVMEIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 + E+ L P G G + G V + ++ I A + G LQIGD+++A Sbjct: 5 TETTEVVLTADPVTGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMA 63 Query: 215 VNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISH 274 +N + ED E+A L+++ + + + S I +S + H+ H Sbjct: 64 INGIPTEDSTFEEANQLLRDSSITSKVTLEIEFDVAESV------IPSSGTFHVKLPKKH 117 Query: 275 SSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE 334 S LG +T +SP P G+ Sbjct: 118 SVELG------ITISSPSSRKP------------------------------------GD 135 Query: 335 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKP 394 + IS I G A +G L GD++L+++ + L + S E A L+ V + + Sbjct: 136 PLVISDIKKGSVAHRTGTLELGDKLLAIDNIRLDSCSMEDAVQILQQCEDLVKLKIRKDE 195 Query: 395 E 395 + Sbjct: 196 D 196 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Query: 321 TGLGFNIVGGED-----GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQA 375 TG G + G IS+I A PA+ G L+ GD+++++NG+ +++ E+A Sbjct: 18 TGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEA 77 Query: 376 AIALKNAGQTVTIIAQYKPEEY 397 L+++ T + + + + Sbjct: 78 NQLLRDSSITSKVTLEIEFDVA 99 >3TR0-A nrPDB Length = 205 Score = 151 bits (380), Expect = 1e-36, Method: Composition-based stats. Identities = 38/172 (22%), Positives = 72/172 (41%), Gaps = 4/172 (2%) Query: 540 LGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFI 599 G K L+ + + HTTRPKR + +G DY F+ + + ++ F+ Sbjct: 16 SGAGKTSLVRALVKALAE-IKISISHTTRPKRPGDQEGVDYFFI-DETRFQAMVKEGAFL 73 Query: 600 EAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVL 659 E YGT V + G+ +L++ R+++ ++IFI P S+E + Sbjct: 74 EHATIYERHYGTEKDWVLRQLKAGRDVLLEIDWQGARQIRELFPPALSIFILPPSIEALR 133 Query: 660 E--INKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIE 709 E I +R + + + E + F +V D+F++ + +I Sbjct: 134 ERLIKRRQDDTAIIEQRLALAREEMAHYKEFDYLVVNDNFDQAVQNLIHIIS 185 >5GJV-C nrPDB Length = 199 Score = 148 bits (374), Expect = 7e-36, Method: Composition-based stats. Identities = 42/202 (20%), Positives = 74/202 (36%), Gaps = 27/202 (13%) Query: 520 VLSYETVTQMEVHYARPIIILGPT------KDRANDDLLSEFPDKFGSCVPHTTRPKREY 573 V Y+ V M RPII++GP+ D L F + TR + Sbjct: 1 VPPYDVVPSM-----RPIILVGPSLKGYEVTDMMQKALFDFLKHLFDGRIS-ITRVTADI 54 Query: 574 EIDGRDYHFVSSREKMEKDIQAHKFIEAGQYNSHL--YGTSVQSVREVAEQGKHCILDVS 631 + R S+ H IE S L + ++ + E+A + LD Sbjct: 55 SLAKRSVLNNPSK---------HIIIERSNTRSSLAEVQSEIERIFELARTLQLVALDAD 105 Query: 632 -ANAVRRLQAAHLHPIAIFIR---PRSLENVLEINKRITEEQARKAFDRATKLEQEFTEC 687 N +L L PI ++I+ P+ L+ +++ + + + KL Q E Sbjct: 106 TINHPAQLSKTSLAPIIVYIKITSPKVLQRLIKSRGKSQSKHLNVQIAASEKLAQCPPEM 165 Query: 688 FSAIVEGDSFEEIYHKVKRVIE 709 F I++ + E+ + +E Sbjct: 166 FDIILDENQLEDACEHLAEYLE 187 >1U3B-A nrPDB Length = 185 Score = 140 bits (353), Expect = 2e-33, Method: Composition-based stats. Identities = 48/204 (23%), Positives = 92/204 (45%), Gaps = 29/204 (14%) Query: 62 EYEEITLER-GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 E++++ +E+ LG I ++ P++ I ++ GG A + G+L + D I+ + Sbjct: 1 EFKDVFIEKQKGEILGVVI---VESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSI 57 Query: 121 NEVDVREV---THSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPK---GLGFSI 174 N + + T + ++ LK S V+L ++R PP V LI+ P LGFS+ Sbjct: 58 NGTSLVGLPLSTCQSIIKGLKN-QSRVKLNIVR-CPPVTTV----LIRRPDLRYQLGFSV 111 Query: 175 AGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKN 234 G+ + ++ GG A + G +++G +I+ +N + HE V L N Sbjct: 112 QNGI------------ICSLMRGGIAERGG-VRVGHRIIEINGQSVVATPHEKIVHILSN 158 Query: 235 TYDVVYLKVAKPSNAYLSDSYAPP 258 +++K + L + P Sbjct: 159 AVGEIHMKTMPAAMYRLLTAQEQP 182 Score = 68.7 bits (166), Expect = 8e-12, Method: Composition-based stats. Identities = 38/200 (19%), Positives = 70/200 (35%), Gaps = 65/200 (32%) Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSN 248 + + ++ GG A K G+L IGD+I+++N L + + +K + +K+ Sbjct: 31 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKL----- 85 Query: 249 AYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIP 308 + R PV L+ D+ Sbjct: 86 -----------------------------------------NIVRCPPVTTVLIRRPDLR 104 Query: 309 REPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 + LGF++ G I ++ GG A+ G +R G +I+ +NG + Sbjct: 105 YQ------------LGFSVQNG------IICSLMRGGIAER-GGVRVGHRIIEINGQSVV 145 Query: 369 NASHEQAAIALKNAGQTVTI 388 HE+ L NA + + Sbjct: 146 ATPHEKIVHILSNAVGEIHM 165 Score = 51.8 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 39/94 (41%), Gaps = 6/94 (6%) Query: 310 EPRRIVIHR-GSTGLGFNIVG---GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV 365 E + + I + LG IV G + I+ ++ GGPA+ SG+L GDQI+S+NG Sbjct: 1 EFKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGT 60 Query: 366 DLRNASHEQAAIALKN--AGQTVTIIAQYKPEEY 397 L +K V + P Sbjct: 61 SLVGLPLSTCQSIIKGLKNQSRVKLNIVRCPPVT 94 >1S4Q-A nrPDB Length = 228 Score = 140 bits (353), Expect = 2e-33, Method: Composition-based stats. Identities = 40/187 (21%), Positives = 74/187 (39%), Gaps = 9/187 (4%) Query: 529 MEVHYARPIIILGP---TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSS 585 R +++ GP K L P+ V TTR R E+DG DYHF+ Sbjct: 18 QPAAVGRVVVLSGPSAVGKSTVVRCLRERIPN-LHFSVSATTRAPRPGEVDGVDYHFIDP 76 Query: 586 REKMEKDIQAHKFIEAGQYNSHLY--GTSVQSVREVAEQGKHCILDVSANAVRRLQAAHL 643 + ++ I + +E + + L+ GT Q VR A G +++V R ++ Sbjct: 77 -TRFQQLIDQGELLEWAEIHGGLHRSGTLAQPVRAAAATGVPVLIEVDLAGARAIKKTMP 135 Query: 644 HPIAIFIRPRSLENVL-EINKRITEE-QARKAFDRATKLEQEFTECFSAIVEGDSFEEIY 701 + +F+ P S +++ + R TE + ++E F +V E Sbjct: 136 EAVTVFLAPPSWQDLQARLIGRGTETADVIQRRLDTARIELAAQGDFDKVVVNRRLESAC 195 Query: 702 HKVKRVI 708 ++ ++ Sbjct: 196 AELVSLL 202 >3SUZ-A nrPDB Length = 388 Score = 136 bits (343), Expect = 2e-32, Method: Composition-based stats. Identities = 52/227 (22%), Positives = 96/227 (42%), Gaps = 33/227 (14%) Query: 39 IVNTDTLEAPGYELQVNGTEGEMEYEEITLER-GNSGLGFSIAGGTDNPHIGDDPSIFIT 97 I+NT + Y + +E+ LE+ LG + ++ P++ + Sbjct: 185 IINTQEM----YNDDLIHFSNSENCKELQLEKHKGEILGVVV---VESGWGSILPTVILA 237 Query: 98 KIIPGGAAAQDGRLRVNDSILFVNEVDVREV---THSAAVEALKEAGSIVRLYVMRRKPP 154 ++ GG AA+ G+L + D I+ +N + + T ++ LK V+L ++ PP Sbjct: 238 NMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKGLKNQTQ-VKLNIV-SCPP 295 Query: 155 AEKVMEIKLIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDK 211 V LIK P LGFS+ G+ + ++ GG A + G +++G + Sbjct: 296 VTTV----LIKRPDLKYQLGFSVQNGI------------ICSLMRGGIAERGG-VRVGHR 338 Query: 212 ILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPP 258 I+ +N + HE V AL N+ +++K + L P Sbjct: 339 IIEINGQSVVATAHEKIVQALSNSVGEIHMKTMPAAMFRLLTGQETP 385 Score = 71.4 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 46/274 (16%), Positives = 96/274 (35%), Gaps = 71/274 (25%) Query: 116 SILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKG-PKGLGFSI 174 L N ++ +++ + + + +E E++L K + LG + Sbjct: 165 EFLRANGINPEDLSQKEYSDIINTQEMYNDDLI--HFSNSENCKELQLEKHKGEILGVVV 222 Query: 175 AGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKN 234 +P + + ++ GG A + G+L IGD+I+++N L + +K Sbjct: 223 VESGWGSILPT---VILANMMNGGPAARSGKLSIGDQIMSINGTSLVGLPLATCQGIIKG 279 Query: 235 TYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRY 294 + +K+ + + P +TT Sbjct: 280 LKNQTQVKL---------NIVSCPPVTT-------------------------------- 298 Query: 295 SPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELR 354 L+ D+ + LGF++ G I ++ GG A+ G +R Sbjct: 299 -----VLIKRPDLKYQ------------LGFSVQNG------IICSLMRGGIAER-GGVR 334 Query: 355 KGDQILSVNGVDLRNASHEQAAIALKNAGQTVTI 388 G +I+ +NG + +HE+ AL N+ + + Sbjct: 335 VGHRIIEINGQSVVATAHEKIVQALSNSVGEIHM 368 >3K1R-A nrPDB Length = 192 Score = 110 bits (275), Expect = 2e-24, Method: Composition-based stats. Identities = 43/165 (26%), Positives = 78/165 (47%), Gaps = 17/165 (10%) Query: 113 VNDSILFVNEVD-VREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIK-GPKGL 170 V D L +NE + + LK +L R + K+ E++L + P+GL Sbjct: 43 VGDLKLVINEPSRLPLFDAIRPLIPLKHQVEYDQLTPRR----SRKLKEVRLDRLHPEGL 98 Query: 171 GFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVA 230 G S+ GG+ ++++ +I+GG A G LQ+GD+I+ +N + HE+ + Sbjct: 99 GLSVRGGL-----EFGCGLFISHLIKGGQADSVG-LQVGDEIVRINGYSISSCTHEEVIN 152 Query: 231 ALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDNEISHS 275 ++ T V +KV + L + PD ++ Q++D +S S Sbjct: 153 LIR-TEKTVSIKVR---HIGLIPVKSSPDEPLTW-QYVDQFVSES 192 Score = 76.0 bits (185), Expect = 5e-14, Method: Composition-based stats. Identities = 33/105 (31%), Positives = 57/105 (54%), Gaps = 7/105 (6%) Query: 292 RRYSPVAKDLLGEEDIPREPRRIVIHRGST----GLGFNIVGG-EDGEGIFISFILAGGP 346 R P+ + ++ PR R++ R GLG ++ GG E G G+FIS ++ GG Sbjct: 63 RPLIPLKHQVEYDQLTPRRSRKLKEVRLDRLHPEGLGLSVRGGLEFGCGLFISHLIKGGQ 122 Query: 347 ADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQ 391 AD G L+ GD+I+ +NG + + +HE+ ++ +TV+I + Sbjct: 123 ADSVG-LQVGDEIVRINGYSISSCTHEEVINLIR-TEKTVSIKVR 165 Score = 65.6 bits (158), Expect = 7e-11, Method: Composition-based stats. Identities = 25/103 (24%), Positives = 46/103 (44%), Gaps = 7/103 (6%) Query: 62 EYEEITLERGN-SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 + +E+ L+R + GLG S+ GG + +FI+ +I GG A G L+V D I+ + Sbjct: 84 KLKEVRLDRLHPEGLGLSVRGGLEF-----GCGLFISHLIKGGQADSVG-LQVGDEIVRI 137 Query: 121 NEVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKL 163 N + TH + ++ ++ P + + L Sbjct: 138 NGYSISSCTHEEVINLIRTEKTVSIKVRHIGLIPVKSSPDEPL 180 >1WFV-A nrPDB Length = 103 Score = 109 bits (271), Expect = 6e-24, Method: Composition-based stats. Identities = 32/98 (32%), Positives = 56/98 (57%), Gaps = 6/98 (6%) Query: 55 NGTEG-EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRV 113 +G+ G + +Y + +E+G G GFSI GG + +++ ++ G A ++GR+RV Sbjct: 3 SGSSGQDFDYFTVDMEKGAKGFGFSIRGGREY-----KMDLYVLRLAEDGPAIRNGRMRV 57 Query: 114 NDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 D I+ +N R++TH+ A+E +K G VRL + R Sbjct: 58 GDQIIEINGESTRDMTHARAIELIKSGGRRVRLLLKRG 95 Score = 97.6 bits (241), Expect = 2e-20, Method: Composition-based stats. Identities = 28/94 (29%), Positives = 50/94 (53%), Gaps = 5/94 (5%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 + + KG KG GFSI GG + +YV ++ E G A ++GR+++GD+I+ +N Sbjct: 13 FTVDMEKGAKGFGFSIRGGREYKM-----DLYVLRLAEDGPAIRNGRMRVGDQIIEINGE 67 Query: 219 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLS 252 D+ H A+ +K+ V L + + + + S Sbjct: 68 STRDMTHARAIELIKSGGRRVRLLLKRGTGSGPS 101 Score = 91.1 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 25/82 (30%), Positives = 47/82 (57%), Gaps = 1/82 (1%) Query: 313 RIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNAS 371 + + +G+ G GF+I GG E +++ + GPA +G +R GDQI+ +NG R+ + Sbjct: 14 TVDMEKGAKGFGFSIRGGREYKMDLYVLRLAEDGPAIRNGRMRVGDQIIEINGESTRDMT 73 Query: 372 HEQAAIALKNAGQTVTIIAQYK 393 H +A +K+ G+ V ++ + Sbjct: 74 HARAIELIKSGGRRVRLLLKRG 95 >2R4H-A nrPDB Length = 112 Score = 107 bits (267), Expect = 2e-23, Method: Composition-based stats. Identities = 29/92 (31%), Positives = 51/92 (55%), Gaps = 5/92 (5%) Query: 60 EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILF 119 M++ + LERG G GFS+ GG + + +++ ++ G A + G++R+ D IL Sbjct: 22 SMDFYTVELERGAKGFGFSLRGGREY-----NMDLYVLRLAEDGPAERSGKMRIGDEILE 76 Query: 120 VNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 +N + + HS A+E +K G VRL++ R Sbjct: 77 INGETTKNMKHSRAIELIKNGGRRVRLFLKRG 108 Score = 95.7 bits (236), Expect = 7e-20, Method: Composition-based stats. Identities = 27/86 (31%), Positives = 48/86 (55%), Gaps = 5/86 (5%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 ++L +G KG GFS+ GG + +YV ++ E G A + G+++IGD+IL +N Sbjct: 28 VELERGAKGFGFSLRGGR-----EYNMDLYVLRLAEDGPAERSGKMRIGDEILEINGETT 82 Query: 221 EDVMHEDAVAALKNTYDVVYLKVAKP 246 +++ H A+ +KN V L + + Sbjct: 83 KNMKHSRAIELIKNGGRRVRLFLKRG 108 Score = 93.4 bits (230), Expect = 3e-19, Method: Composition-based stats. Identities = 30/96 (31%), Positives = 53/96 (55%), Gaps = 4/96 (4%) Query: 302 LGEEDIPREPR---RIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGD 357 LG E++ + + + RG+ G GF++ GG E +++ + GPA+ SG++R GD Sbjct: 13 LGTENLYFQSMDFYTVELERGAKGFGFSLRGGREYNMDLYVLRLAEDGPAERSGKMRIGD 72 Query: 358 QILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYK 393 +IL +NG +N H +A +KN G+ V + + Sbjct: 73 EILEINGETTKNMKHSRAIELIKNGGRRVRLFLKRG 108 >2JIL-A nrPDB Length = 97 Score = 106 bits (264), Expect = 3e-23, Method: Composition-based stats. Identities = 27/91 (29%), Positives = 45/91 (49%), Gaps = 1/91 (1%) Query: 60 EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILF 119 M E+TL + + GF I GG + P + IT + PGG A ++G ++ D +L Sbjct: 1 SMRTVEVTLHKEGNTFGFVIRGGAHDDRNKSRP-VVITSVRPGGPADREGTIKPGDRLLS 59 Query: 120 VNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 V+ + + TH+ A+ LK+ G L + Sbjct: 60 VDGIRLLGTTHAEAMSILKQCGQEAALLIEY 90 Score = 99.5 bits (246), Expect = 4e-21, Method: Composition-based stats. Identities = 28/91 (30%), Positives = 47/91 (51%), Gaps = 5/91 (5%) Query: 313 RIVIHRGSTGLGFNIVGGEDGE-----GIFISFILAGGPADLSGELRKGDQILSVNGVDL 367 + +H+ GF I GG + + I+ + GGPAD G ++ GD++LSV+G+ L Sbjct: 6 EVTLHKEGNTFGFVIRGGAHDDRNKSRPVVITSVRPGGPADREGTIKPGDRLLSVDGIRL 65 Query: 368 RNASHEQAAIALKNAGQTVTIIAQYKPEEYS 398 +H +A LK GQ ++ +Y E + Sbjct: 66 LGTTHAEAMSILKQCGQEAALLIEYDVSETA 96 Score = 84.5 bits (207), Expect = 1e-16, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 1/87 (1%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 + +E+ L K GF I GG + + +T + GG A ++G ++ GD++L+V+ Sbjct: 3 RTVEVTLHKEGNTFGFVIRGGA-HDDRNKSRPVVITSVRPGGPADREGTIKPGDRLLSVD 61 Query: 217 SVGLEDVMHEDAVAALKNTYDVVYLKV 243 + L H +A++ LK L + Sbjct: 62 GIRLLGTTHAEAMSILKQCGQEAALLI 88 >5ZDS-A nrPDB Length = 96 Score = 101 bits (250), Expect = 2e-21, Method: Composition-based stats. Identities = 35/97 (36%), Positives = 53/97 (54%), Gaps = 4/97 (4%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 GE+ + E+ E G LGFS+ GG + I++ IIPGG AA++G++ Sbjct: 3 QTNTGEIYFVELVKEDG--TLGFSVTGGINT--SVPHGGIYVKSIIPGGPAAKEGQILQG 58 Query: 115 DSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 D +L V+ V + +TH AV+ LK G + RL + RR Sbjct: 59 DRLLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERR 95 Score = 94.1 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 33/87 (37%), Positives = 49/87 (56%), Gaps = 2/87 (2%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 ++L+K LGFS+ GG+ N +P IYV II GG A K+G++ GD++L V+ V L Sbjct: 12 VELVKEDGTLGFSVTGGI-NTSVP-HGGIYVKSIIPGGPAAKEGQILQGDRLLQVDGVSL 69 Query: 221 EDVMHEDAVAALKNTYDVVYLKVAKPS 247 + H+ AV LK V L + + Sbjct: 70 CGLTHKQAVQCLKGPGQVARLVLERRG 96 Score = 92.6 bits (228), Expect = 5e-19, Method: Composition-based stats. Identities = 29/96 (30%), Positives = 51/96 (53%), Gaps = 4/96 (4%) Query: 303 GEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE----GIFISFILAGGPADLSGELRKGDQ 358 G + E + + + LGF++ GG + GI++ I+ GGPA G++ +GD+ Sbjct: 1 GSQTNTGEIYFVELVKEDGTLGFSVTGGINTSVPHGGIYVKSIIPGGPAAKEGQILQGDR 60 Query: 359 ILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKP 394 +L V+GV L +H+QA LK GQ ++ + + Sbjct: 61 LLQVDGVSLCGLTHKQAVQCLKGPGQVARLVLERRG 96 >3TSV-A nrPDB Length = 124 Score = 100 bits (248), Expect = 3e-21, Method: Composition-based stats. Identities = 38/97 (39%), Positives = 52/97 (53%), Gaps = 4/97 (4%) Query: 305 EDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNG 364 I R ++V R +G + GG D GIF++ +L PA G L +GDQIL VN Sbjct: 23 HMILRPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNN 80 Query: 365 VDLRNASHEQAAIALKN--AGQTVTIIAQYKPEEYSR 399 VD N E+A + L + G+ VTI+AQ K + Y R Sbjct: 81 VDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVYRR 117 Score = 66.4 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 31/96 (32%), Positives = 50/96 (52%), Gaps = 12/96 (12%) Query: 159 MEIKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN Sbjct: 28 PSMKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVN 79 Query: 217 SVGLEDVMHEDAVAALKN--TYDVVYLKVAKPSNAY 250 +V +++ E+AV L + + V + K + Y Sbjct: 80 NVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVY 115 Score = 57.2 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 26/96 (27%), Positives = 42/96 (43%), Gaps = 10/96 (10%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 R +G +AGG D IF+ ++ AA++G L D IL VN VD + Sbjct: 36 RKGDSVGLRLAGGND-------VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNII 87 Query: 130 HSAAVEALKE--AGSIVRLYVMRRKPPAEKVMEIKL 163 AV L + G V + ++K +++E + Sbjct: 88 REEAVLFLLDLPKGEEVTILAQKKKDVYRRIVESDV 123 >3EGH-C nrPDB Length = 170 Score = 98.8 bits (244), Expect = 7e-21, Method: Composition-based stats. Identities = 32/101 (31%), Positives = 52/101 (51%), Gaps = 1/101 (0%) Query: 147 YVMRRKPPAEKVMEIKLIKGPKGLGFSIAG-GVGNQHIPGDNSIYVTKIIEGGAAHKDGR 205 Y + ++ ++ ++L K +GLG SI G G G I+V + EGGAAH+DGR Sbjct: 70 YELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAAHRDGR 129 Query: 206 LQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKP 246 +Q+ D ++ V+ L V A + L+NT V + + Sbjct: 130 IQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRE 170 Score = 93.0 bits (229), Expect = 5e-19, Method: Composition-based stats. Identities = 33/106 (31%), Positives = 51/106 (48%), Gaps = 1/106 (0%) Query: 47 APGYELQVNGTEGEMEYEEITLERGNSGLGFSIAG-GTDNPHIGDDPSIFITKIIPGGAA 105 A E ++ +E + LE+ + GLG SI G G + IF+ + GGAA Sbjct: 65 AASAEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGADMGLEKLGIFVKTVTEGGAA 124 Query: 106 AQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 +DGR++VND ++ V+ + VT S A L+ VR + R Sbjct: 125 HRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVRFMIGRE 170 Score = 68.3 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 32/126 (25%), Positives = 52/126 (41%), Gaps = 9/126 (7%) Query: 275 SSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVG----- 329 S+Y DY P S A+ L + E + + + S GLG +I+G Sbjct: 47 STYSNEDYDRRNEDVDPMAAS--AEYELEKRVERLELFPVELEKDSEGLGISIIGMGAGA 104 Query: 330 --GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVT 387 G + GIF+ + GG A G ++ D ++ V+G L + AA L+N V Sbjct: 105 DMGLEKLGIFVKTVTEGGAAHRDGRIQVNDLLVEVDGTSLVGVTQSFAASVLRNTKGRVR 164 Query: 388 IIAQYK 393 + + Sbjct: 165 FMIGRE 170 >5ZYS-A nrPDB Length = 97 Score = 98.4 bits (243), Expect = 1e-20, Method: Composition-based stats. Identities = 32/98 (32%), Positives = 50/98 (51%), Gaps = 7/98 (7%) Query: 56 GTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVND 115 G+ + + ++I L R +G GF I GG + I+I I+P GAA DGRLR D Sbjct: 3 GSIPDYQEQDIFLWRKETGFGFRILGGNE-----PGEPIYIGHIVPLGAADTDGRLRSGD 57 Query: 116 SILFVNEVDVREVTHSAAVEALKEAGSI--VRLYVMRR 151 ++ V+ V +H V+ +++A V L V R+ Sbjct: 58 ELICVDGTPVIGKSHQLVVQLMQQAAKQGHVNLTVRRK 95 Score = 86.1 bits (211), Expect = 4e-17, Method: Composition-based stats. Identities = 30/87 (34%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Query: 310 EPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 + + I + R TG GF I+GG E GE I+I I+ G AD G LR GD+++ V+G + Sbjct: 9 QEQDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELICVDGTPVI 68 Query: 369 NASHEQAAIALKNAGQT--VTIIAQYK 393 SH+ ++ A + V + + K Sbjct: 69 GKSHQLVVQLMQQAAKQGHVNLTVRRK 95 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 28/88 (31%), Positives = 44/88 (50%), Gaps = 7/88 (7%) Query: 160 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG 219 +I L + G GF I GG + PG+ IY+ I+ GAA DGRL+ GD+++ V+ Sbjct: 12 DIFLWRKETGFGFRILGG----NEPGE-PIYIGHIVPLGAADTDGRLRSGDELICVDGTP 66 Query: 220 LEDVMHEDAVAALKNT--YDVVYLKVAK 245 + H+ V ++ V L V + Sbjct: 67 VIGKSHQLVVQLMQQAAKQGHVNLTVRR 94 >4OEP-A nrPDB Length = 107 Score = 98.0 bits (242), Expect = 1e-20, Method: Composition-based stats. Identities = 35/99 (35%), Positives = 57/99 (57%), Gaps = 4/99 (4%) Query: 56 GTEGEMEYEEITLERG-NSGLGFSIAGGTDNPHI-GDDPSIFITKIIPGGAAAQDGRLRV 113 G+ E +TL R G G +I+GG DNPH + SI I+ ++ GG A +G+L+ Sbjct: 1 GSHMIWEQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPA--EGQLQE 58 Query: 114 NDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK 152 ND + VN V + V H+ AV+ L+++G ++ + R+K Sbjct: 59 NDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKK 97 Score = 86.4 bits (212), Expect = 3e-17, Method: Composition-based stats. Identities = 28/94 (29%), Positives = 49/94 (52%), Gaps = 4/94 (4%) Query: 161 IKLIKGPK-GLGFSIAGGVGNQHI-PGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 + L + P G G +I+GG N H G+ SI ++ +++GG A G+LQ D++ VN V Sbjct: 11 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQENDRVAMVNGV 68 Query: 219 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLS 252 +++V H AV L+ + + + + S Sbjct: 69 SMDNVEHAFAVQQLRKSGKNAKITIRRKKGGGSS 102 Score = 86.1 bits (211), Expect = 5e-17, Method: Composition-based stats. Identities = 33/100 (33%), Positives = 47/100 (47%), Gaps = 11/100 (11%) Query: 303 GEEDIPREPRRIVIHRG-STGLGFNIVGGEDGE-------GIFISFILAGGPADLSGELR 354 G I E + +HR G G I GG D I IS +L GGPA+ G+L+ Sbjct: 1 GSHMIW-EQHTVTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLKGGPAE--GQLQ 57 Query: 355 KGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKP 394 + D++ VNGV + N H A L+ +G+ I + K Sbjct: 58 ENDRVAMVNGVSMDNVEHAFAVQQLRKSGKNAKITIRRKK 97 >1UEQ-A nrPDB Length = 123 Score = 96.8 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 35/105 (33%), Positives = 53/105 (50%), Gaps = 12/105 (11%) Query: 53 QVNGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLR 112 Q+ GT + TL++ N G GF+I GG + D + + +IP G AAQDG++ Sbjct: 15 QLKGT-----FLSTTLKKSNMGFGFTIIGGDE-----PDEFLQVKSVIPDGPAAQDGKME 64 Query: 113 VNDSILFVNEVDVREVTHSAAVEALKEA--GSIVRLYVMRRKPPA 155 D I+++NEV V TH+ V+ + G V L + R P Sbjct: 65 TGDVIVYINEVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLP 109 Score = 74.1 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 40/79 (50%), Gaps = 3/79 (3%) Query: 315 VIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 + + + G GF I+GG E E + + ++ GPA G++ GD I+ +N V + +H Sbjct: 24 TLKKSNMGFGFTIIGGDEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYINEVCVLGHTHA 83 Query: 374 QAAIALKNA--GQTVTIIA 390 ++ GQ+V ++ Sbjct: 84 DVVKLFQSVPIGQSVNLVL 102 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 40/100 (40%), Gaps = 7/100 (7%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 + L K G GF+I GG D + V +I G A +DG+++ GD I+ +N Sbjct: 19 TFLSTTLKKSNMGFGFTIIGG-----DEPDEFLQVKSVIPDGPAAQDGKMETGDVIVYIN 73 Query: 217 SVGLEDVMHEDAVAALKNT--YDVVYLKVAKPSNAYLSDS 254 V + H D V ++ V L + + Sbjct: 74 EVCVLGHTHADVVKLFQSVPIGQSVNLVLCRGYPLPFDPE 113 >1X6D-A nrPDB Length = 119 Score = 95.3 bits (235), Expect = 8e-20, Method: Composition-based stats. Identities = 26/98 (26%), Positives = 52/98 (53%), Gaps = 4/98 (4%) Query: 64 EEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEV 123 I + +GLGFS+AGG D ++ I + ++ P G A+Q+G ++ + +L +N Sbjct: 18 VTILHKEEGAGLGFSLAGGAD----LENKVITVHRVFPNGLASQEGTIQKGNEVLSINGK 73 Query: 124 DVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEI 161 ++ TH A+ L++A + ++ RK E + ++ Sbjct: 74 SLKGTTHHDALAILRQAREPRQAVIVTRKLTPEAMPDL 111 Score = 78.3 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 28/90 (31%), Positives = 46/90 (51%), Gaps = 6/90 (6%) Query: 312 RRIVIHRG-STGLGFNIVGGEDGEGIFIS--FILAGGPADLSGELRKGDQILSVNGVDLR 368 ++H+ GLGF++ GG D E I+ + G A G ++KG+++LS+NG L+ Sbjct: 17 HVTILHKEEGAGLGFSLAGGADLENKVITVHRVFPNGLASQEGTIQKGNEVLSINGKSLK 76 Query: 369 NASHEQAAIALKNA---GQTVTIIAQYKPE 395 +H A L+ A Q V + + PE Sbjct: 77 GTTHHDALAILRQAREPRQAVIVTRKLTPE 106 Score = 75.3 bits (183), Expect = 1e-13, Method: Composition-based stats. Identities = 30/109 (27%), Positives = 54/109 (49%), Gaps = 10/109 (9%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 + I + GLGFS+AGG + + I V ++ G A ++G +Q G+++L++N Sbjct: 18 VTILHKEEGAGLGFSLAGGADLE----NKVITVHRVFPNGLASQEGTIQKGNEVLSINGK 73 Query: 219 GLEDVMHEDAVAALKNTYD-VVYLKVAKPSNAYLSDSYAPPDITTSYSQ 266 L+ H DA+A L+ + + V + L+ A PD+ +S Sbjct: 74 SLKGTTHHDALAILRQAREPRQAVIVTRK----LTPE-AMPDLNSSGPS 117 >1UEZ-A nrPDB Length = 101 Score = 93.8 bits (231), Expect = 3e-19, Method: Composition-based stats. Identities = 33/90 (36%), Positives = 54/90 (60%), Gaps = 6/90 (6%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 +G+ GE+ + + + GLGFSI GG+++ I+++ + PG A ++G LRV Sbjct: 3 SGSSGEVRLVSLRRAKAHEGLGFSIRGGSEH-----GVGIYVSLVEPGSLAEKEG-LRVG 56 Query: 115 DSILFVNEVDVREVTHSAAVEALKEAGSIV 144 D IL VN+ + VTH+ AV+ALK + +V Sbjct: 57 DQILRVNDKSLARVTHAEAVKALKGSKKLV 86 Score = 82.2 bits (201), Expect = 7e-16, Method: Composition-based stats. Identities = 32/83 (38%), Positives = 48/83 (57%), Gaps = 6/83 (7%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +++ ++ K +GLGFSI GG + IYV+ + G A K+G L++GD+IL VN Sbjct: 10 RLVSLRRAKAHEGLGFSIRGGSEH-----GVGIYVSLVEPGSLAEKEG-LRVGDQILRVN 63 Query: 217 SVGLEDVMHEDAVAALKNTYDVV 239 L V H +AV ALK + +V Sbjct: 64 DKSLARVTHAEAVKALKGSKKLV 86 Score = 80.3 bits (196), Expect = 3e-15, Method: Composition-based stats. Identities = 35/87 (40%), Positives = 46/87 (52%), Gaps = 4/87 (4%) Query: 303 GEEDIPREPRRIVIHRG--STGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQI 359 G E R + + R GLGF+I GG E G GI++S + G A+ G LR GDQI Sbjct: 1 GSSGSSGEVRLVSLRRAKAHEGLGFSIRGGSEHGVGIYVSLVEPGSLAEKEG-LRVGDQI 59 Query: 360 LSVNGVDLRNASHEQAAIALKNAGQTV 386 L VN L +H +A ALK + + V Sbjct: 60 LRVNDKSLARVTHAEAVKALKGSKKLV 86 >1MFG-A nrPDB Length = 95 Score = 93.4 bits (230), Expect = 3e-19, Method: Composition-based stats. Identities = 34/91 (37%), Positives = 51/91 (56%), Gaps = 6/91 (6%) Query: 159 MEIKLIKGPKGLGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAV 215 + +++ K P+ LGFSI+GGVG N P D+ I+VT++ G A K LQ GDKI+ Sbjct: 5 IRVRVEKDPE-LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQA 61 Query: 216 NSVGLEDVMHEDAVAALKNTYDVVYLKVAKP 246 N ++ H AV+ LK + V L + + Sbjct: 62 NGYSFINIEHGQAVSLLKTFQNTVELIIVRE 92 Score = 86.8 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%) Query: 59 GEMEYEEITLERGNSGLGFSIAGG---TDNPHIGDDPSIFITKIIPGGAAAQDGRLRVND 115 G ME + +E+ LGFSI+GG NP DD IF+T++ P G A++ L+ D Sbjct: 1 GSME-IRVRVEKDPE-LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGD 56 Query: 116 SILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 I+ N + H AV LK + V L ++R Sbjct: 57 KIIQANGYSFINIEHGQAVSLLKTFQNTVELIIVRE 92 Score = 77.6 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 11/86 (12%) Query: 319 GSTGLGFNIVGG---------EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 LGF+I GG D +GIF++ + GPA L+ GD+I+ NG N Sbjct: 11 KDPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFIN 68 Query: 370 ASHEQAAIALKNAGQTVTIIAQYKPE 395 H QA LK TV +I + Sbjct: 69 IEHGQAVSLLKTFQNTVELIIVREVS 94 >2QBW-A nrPDB Length = 195 Score = 92.2 bits (227), Expect = 8e-19, Method: Composition-based stats. Identities = 33/103 (32%), Positives = 51/103 (49%), Gaps = 6/103 (5%) Query: 75 LGFSIAGG---TDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHS 131 LGFSI+GG NP DD IF+T++ P G A++ L+ D I+ N + H Sbjct: 4 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHG 61 Query: 132 AAVEALKEAGSIVRLYVMRRK-PPAEKVMEIKLIKGPKGLGFS 173 AV LK + V L ++R A++ + +++ K G S Sbjct: 62 QAVSLLKTFQNTVELIIVREVGNGAKQEIRVRVEKDGGSGGVS 104 Score = 91.4 bits (225), Expect = 1e-18, Method: Composition-based stats. Identities = 32/88 (36%), Positives = 44/88 (50%), Gaps = 5/88 (5%) Query: 170 LGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHE 226 LGFSI+GGVG N P D+ I+VT++ G A K LQ GDKI+ N ++ H Sbjct: 4 LGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINIEHG 61 Query: 227 DAVAALKNTYDVVYLKVAKPSNAYLSDS 254 AV+ LK + V L + + Sbjct: 62 QAVSLLKTFQNTVELIIVREVGNGAKQE 89 Score = 82.6 bits (202), Expect = 6e-16, Method: Composition-based stats. Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 17/112 (15%) Query: 320 STGLGFNIVGG---------EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 S LGF+I GG D +GIF++ + GPA L+ GD+I+ NG N Sbjct: 1 SPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFINI 58 Query: 371 SHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTAS 422 H QA LK TV +I + ++ E ++ + GSG S Sbjct: 59 EHGQAVSLLKTFQNTVELIIVREVGNGAKQEIRVR------VEKDGGSGGVS 104 >3CH8-A nrPDB Length = 195 Score = 91.8 bits (226), Expect = 1e-18, Method: Composition-based stats. Identities = 34/107 (31%), Positives = 53/107 (49%), Gaps = 6/107 (5%) Query: 71 GNSGLGFSIAGG---TDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 G+ LGFSI+GG NP DD IF+T++ P G A++ L+ D I+ N Sbjct: 1 GSPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFIN 58 Query: 128 VTHSAAVEALKEAGSIVRLYVMRRKPP-AEKVMEIKLIKGPKGLGFS 173 + H AV LK + V L ++R A++ + +++ K G S Sbjct: 59 IEHGQAVSLLKTFQNTVELIIVREVGNGAKQEIRVRVEKDGGSGGVS 105 Score = 91.1 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 33/92 (35%), Positives = 45/92 (48%), Gaps = 5/92 (5%) Query: 166 GPKGLGFSIAGGVG---NQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 G LGFSI+GGVG N P D+ I+VT++ G A K LQ GDKI+ N + Sbjct: 1 GSPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFIN 58 Query: 223 VMHEDAVAALKNTYDVVYLKVAKPSNAYLSDS 254 + H AV+ LK + V L + + Sbjct: 59 IEHGQAVSLLKTFQNTVELIIVREVGNGAKQE 90 Score = 83.7 bits (205), Expect = 2e-16, Method: Composition-based stats. Identities = 36/145 (24%), Positives = 58/145 (40%), Gaps = 14/145 (9%) Query: 319 GSTGLGFNIVGG---------EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 GS LGF+I GG D +GIF++ + GPA L+ GD+I+ NG N Sbjct: 1 GSPELGFSISGGVGGRGNPFRPDDDGIFVTRVQPEGPASK--LLQPGDKIIQANGYSFIN 58 Query: 370 ASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKR 429 H QA LK TV +I + ++ E ++ R + S G + Sbjct: 59 IEHGQAVSLLKTFQNTVELIIVREVGNGAKQEIRV---RVEKDGGSGGVSSVPTNLEVVA 115 Query: 430 GFYIRALFDYDKTKDCGFLSQALSF 454 L +D ++ +++ Sbjct: 116 ATPTSLLISWDAYRELPVSYYRITY 140 >3SHU-A nrPDB Length = 95 Score = 91.4 bits (225), Expect = 1e-18, Method: Composition-based stats. Identities = 36/91 (39%), Positives = 50/91 (54%), Gaps = 4/91 (4%) Query: 311 PRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 ++V R +G + GG D GIF++ +L PA G L +GDQIL VN VD N Sbjct: 4 SMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNI 61 Query: 371 SHEQAAIALKN--AGQTVTIIAQYKPEEYSR 399 E+A + L + G+ VTI+AQ K + Y R Sbjct: 62 IREEAVLFLLDLPKGEEVTILAQKKKDVYRR 92 Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 31/95 (32%), Positives = 50/95 (52%), Gaps = 12/95 (12%) Query: 160 EIKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS 217 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN+ Sbjct: 4 SMKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVNN 55 Query: 218 VGLEDVMHEDAVAALKN--TYDVVYLKVAKPSNAY 250 V +++ E+AV L + + V + K + Y Sbjct: 56 VDFTNIIREEAVLFLLDLPKGEEVTILAQKKKDVY 90 Score = 55.2 bits (131), Expect = 9e-08, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 41/93 (44%), Gaps = 10/93 (10%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 R +G +AGG D IF+ ++ AA++G L D IL VN VD + Sbjct: 11 RKGDSVGLRLAGGND-------VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNII 62 Query: 130 HSAAVEALKE--AGSIVRLYVMRRKPPAEKVME 160 AV L + G V + ++K +++E Sbjct: 63 REEAVLFLLDLPKGEEVTILAQKKKDVYRRIVE 95 >4Q2Q-A nrPDB Length = 102 Score = 91.1 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 36/94 (38%), Positives = 49/94 (52%), Gaps = 6/94 (6%) Query: 303 GEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSV 362 G R ++V R +G + GG D GIF++ +L PA G L +GDQIL V Sbjct: 1 GSHM--RPSMKLVKFRKGDSVGLRLAGGND-VGIFVAGVLEDSPAAKEG-LEEGDQILRV 56 Query: 363 NGVDLRNASHEQAAIALKN--AGQTVTIIAQYKP 394 N VD N E+A + L + G+ VTI+AQ K Sbjct: 57 NNVDFTNIIREEAVLFLLDLPKGEEVTILAQKKK 90 Score = 66.8 bits (161), Expect = 3e-11, Method: Composition-based stats. Identities = 31/96 (32%), Positives = 49/96 (51%), Gaps = 12/96 (12%) Query: 159 MEIKLIKGPKG--LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +KL+K KG +G +AGG D I+V ++E A K+G L+ GD+IL VN Sbjct: 6 PSMKLVKFRKGDSVGLRLAGG-------NDVGIFVAGVLEDSPAAKEG-LEEGDQILRVN 57 Query: 217 SVGLEDVMHEDAVAALKN--TYDVVYLKVAKPSNAY 250 +V +++ E+AV L + + V + K A Sbjct: 58 NVDFTNIIREEAVLFLLDLPKGEEVTILAQKKKAAG 93 Score = 53.3 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 8/83 (9%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 R +G +AGG D IF+ ++ AA++G L D IL VN VD + Sbjct: 14 RKGDSVGLRLAGGND-------VGIFVAGVLEDSPAAKEG-LEEGDQILRVNNVDFTNII 65 Query: 130 HSAAVEALKEAGSIVRLYVMRRK 152 AV L + + ++ +K Sbjct: 66 REEAVLFLLDLPKGEEVTILAQK 88 >2Q9V-A nrPDB Length = 90 Score = 89.5 bits (220), Expect = 5e-18, Method: Composition-based stats. Identities = 28/89 (31%), Positives = 44/89 (49%), Gaps = 5/89 (5%) Query: 63 YEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNE 122 ++I L R +G GF I GG + I+I I+P GAA DGRLR D ++ V+ Sbjct: 3 EQDIFLWRKETGFGFRILGGNE-----PGEPIYIGHIVPLGAADTDGRLRSGDELISVDG 57 Query: 123 VDVREVTHSAAVEALKEAGSIVRLYVMRR 151 V +H V+ +++A + + R Sbjct: 58 TPVIGKSHQLVVQLMQQAAKQGHVNLTVR 86 Score = 86.8 bits (213), Expect = 3e-17, Method: Composition-based stats. Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 312 RRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 + I + R TG GF I+GG E GE I+I I+ G AD G LR GD+++SV+G + Sbjct: 4 QDIFLWRKETGFGFRILGGNEPGEPIYIGHIVPLGAADTDGRLRSGDELISVDGTPVIGK 63 Query: 371 SHEQAAIALKNAGQT--VTIIAQYKP 394 SH+ ++ A + V + + Sbjct: 64 SHQLVVQLMQQAAKQGHVNLTVRQTR 89 Score = 58.7 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 28/90 (31%), Positives = 45/90 (50%), Gaps = 7/90 (7%) Query: 160 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG 219 +I L + G GF I GG + PG+ IY+ I+ GAA DGRL+ GD++++V+ Sbjct: 5 DIFLWRKETGFGFRILGG----NEPGE-PIYIGHIVPLGAADTDGRLRSGDELISVDGTP 59 Query: 220 LEDVMHEDAVAALKNT--YDVVYLKVAKPS 247 + H+ V ++ V L V + Sbjct: 60 VIGKSHQLVVQLMQQAAKQGHVNLTVRQTR 89 >1UEP-A nrPDB Length = 103 Score = 89.5 bits (220), Expect = 5e-18, Method: Composition-based stats. Identities = 32/100 (32%), Positives = 48/100 (48%), Gaps = 9/100 (9%) Query: 56 GTEGEMEYEE--ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRV 113 G+ G Y+E + L R SG GF I GG + I I +I G+A +DGRL Sbjct: 1 GSSGSSGYKELDVHLRRMESGFGFRILGGDE-----PGQPILIGAVIAMGSADRDGRLHP 55 Query: 114 NDSILFVNEVDVREVTHSAAVEALKEAGSI--VRLYVMRR 151 D +++V+ + V TH ++ + A V L V R+ Sbjct: 56 GDELVYVDGIPVAGKTHRYVIDLMHHAARNGQVNLTVRRK 95 Score = 78.3 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 25/83 (30%), Positives = 44/83 (53%), Gaps = 3/83 (3%) Query: 314 IVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 + + R +G GF I+GG E G+ I I ++A G AD G L GD+++ V+G+ + +H Sbjct: 13 VHLRRMESGFGFRILGGDEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGIPVAGKTH 72 Query: 373 EQAAIALKNAGQT--VTIIAQYK 393 + +A + V + + K Sbjct: 73 RYVIDLMHHAARNGQVNLTVRRK 95 Score = 54.1 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 40/89 (44%), Gaps = 7/89 (7%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 +++ L + G GF I GG I + +I G+A +DGRL GD+++ V+ + Sbjct: 11 LDVHLRRMESGFGFRILGG-----DEPGQPILIGAVIAMGSADRDGRLHPGDELVYVDGI 65 Query: 219 GLEDVMHEDAVAALKNTY--DVVYLKVAK 245 + H + + + V L V + Sbjct: 66 PVAGKTHRYVIDLMHHAARNGQVNLTVRR 94 >2LOB-A nrPDB Length = 112 Score = 89.1 bits (219), Expect = 6e-18, Method: Composition-based stats. Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 5/85 (5%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + L+ + GLG SI GG ++ I I++I PG A + G L V D+IL VN V++ Sbjct: 32 LLLKEDHEGLGISITGGKEH-----GVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 86 Query: 126 REVTHSAAVEALKEAGSIVRLYVMR 150 R+ H AV L + + V+ Sbjct: 87 RDTKHKEAVTILSQQRGEIEFEVVY 111 Score = 86.1 bits (211), Expect = 5e-17, Method: Composition-based stats. Identities = 36/96 (37%), Positives = 46/96 (47%), Gaps = 14/96 (14%) Query: 294 YSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGE 352 + + K LL +ED GLG +I GG E G I IS I G PAD G Sbjct: 25 FQGIRKVLLLKED-------------HEGLGISITGGKEHGVPILISEIHPGQPADRCGG 71 Query: 353 LRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTI 388 L GD IL+VNGV+LR+ H++A L + Sbjct: 72 LHVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEF 107 Score = 85.7 bits (210), Expect = 6e-17, Method: Composition-based stats. Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 5/82 (6%) Query: 163 LIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 L + +GLG SI GG I +++I G A + G L +GD ILAVN V L D Sbjct: 34 LKEDHEGLGISITGG-----KEHGVPILISEIHPGQPADRCGGLHVGDAILAVNGVNLRD 88 Query: 223 VMHEDAVAALKNTYDVVYLKVA 244 H++AV L + +V Sbjct: 89 TKHKEAVTILSQQRGEIEFEVV 110 >2DC2-A nrPDB Length = 103 Score = 88.7 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 14/95 (14%) Query: 295 SPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGEL 353 P+ K LL +ED GLG +I GG E G I IS I G PAD G L Sbjct: 8 GPIRKVLLLKED-------------HEGLGISITGGKEHGVPILISEIHPGQPADRCGGL 54 Query: 354 RKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTI 388 GD IL+VNGV+LR+ H++A L + Sbjct: 55 HVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEF 89 Score = 88.4 bits (217), Expect = 1e-17, Method: Composition-based stats. Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 5/85 (5%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + L+ + GLG SI GG ++ I I++I PG A + G L V D+IL VN V++ Sbjct: 14 LLLKEDHEGLGISITGGKEH-----GVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 68 Query: 126 REVTHSAAVEALKEAGSIVRLYVMR 150 R+ H AV L + + V+ Sbjct: 69 RDTKHKEAVTILSQQRGEIEFEVVY 93 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 154 PAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKIL 213 P KV+ +K + +GLG SI GG I +++I G A + G L +GD IL Sbjct: 9 PIRKVLLLK--EDHEGLGISITGG-----KEHGVPILISEIHPGQPADRCGGLHVGDAIL 61 Query: 214 AVNSVGLEDVMHEDAVAALKNTYDVVYLKVA 244 AVN V L D H++AV L + +V Sbjct: 62 AVNGVNLRDTKHKEAVTILSQQRGEIEFEVV 92 >4JOF-A nrPDB Length = 87 Score = 88.7 bits (218), Expect = 7e-18, Method: Composition-based stats. Identities = 37/95 (38%), Positives = 46/95 (48%), Gaps = 14/95 (14%) Query: 295 SPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGEL 353 P+ K LL +ED GLG +I GG E G I IS I G PAD G L Sbjct: 1 GPIRKVLLLKED-------------HEGLGISITGGKEHGVPILISEIHPGQPADRCGGL 47 Query: 354 RKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTI 388 GD IL+VNGV+LR+ H++A L + Sbjct: 48 HVGDAILAVNGVNLRDTKHKEAVTILSQQRGEIEF 82 Score = 88.4 bits (217), Expect = 1e-17, Method: Composition-based stats. Identities = 29/85 (34%), Positives = 44/85 (51%), Gaps = 5/85 (5%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + L+ + GLG SI GG ++ I I++I PG A + G L V D+IL VN V++ Sbjct: 7 LLLKEDHEGLGISITGGKEH-----GVPILISEIHPGQPADRCGGLHVGDAILAVNGVNL 61 Query: 126 REVTHSAAVEALKEAGSIVRLYVMR 150 R+ H AV L + + V+ Sbjct: 62 RDTKHKEAVTILSQQRGEIEFEVVY 86 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 32/91 (35%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 154 PAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKIL 213 P KV+ +K + +GLG SI GG I +++I G A + G L +GD IL Sbjct: 2 PIRKVLLLK--EDHEGLGISITGG-----KEHGVPILISEIHPGQPADRCGGLHVGDAIL 54 Query: 214 AVNSVGLEDVMHEDAVAALKNTYDVVYLKVA 244 AVN V L D H++AV L + +V Sbjct: 55 AVNGVNLRDTKHKEAVTILSQQRGEIEFEVV 85 >2KBS-A nrPDB Length = 92 Score = 88.0 bits (216), Expect = 1e-17, Method: Composition-based stats. Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Query: 309 REPRRIVIHRGSTGLGFNIVGGE-DGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 367 +E + + GS GLG +I G GIFIS + G + G L GDQI+ VNGVD Sbjct: 1 KEKKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDF 59 Query: 368 RNASHEQAAIALKNAGQ-TVTIIAQYKPEEY 397 N H++A LK++ T++I+A E + Sbjct: 60 SNLDHKEAVNVLKSSRSLTISIVAAAGRELF 90 Score = 75.3 bits (183), Expect = 9e-14, Method: Composition-based stats. Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 71 GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 G+ GLG SI+ G P IFI+ + PG +A+ G L + D I+ VN VD + H Sbjct: 11 GSRGLGCSISSGPIQ-----KPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSNLDH 64 Query: 131 SAAVEALKEAGSI 143 AV LK + S+ Sbjct: 65 KEAVNVLKSSRSL 77 Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 23/70 (32%), Positives = 41/70 (58%), Gaps = 6/70 (8%) Query: 166 GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMH 225 G +GLG SI+ G + I+++ + G + + G L+IGD+I+ VN V ++ H Sbjct: 11 GSRGLGCSISSGPIQK-----PGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSNLDH 64 Query: 226 EDAVAALKNT 235 ++AV LK++ Sbjct: 65 KEAVNVLKSS 74 >1T0J-A nrPDB Length = 132 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 27/87 (31%), Positives = 35/87 (40%), Gaps = 6/87 (6%) Query: 430 GFYIRALFDYDK--TKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y D A+SF D LHV + + +WW R V E IGF Sbjct: 48 AFAVRTNVRYSAAQEDDVPVPGMAISFEAKDFLHVKEKFNNDWWIGRLVKEGCE---IGF 104 Query: 488 IPSKRRVER-REWSRLKAKDWGSSSGS 513 IPS ++E R +AK S Sbjct: 105 IPSPVKLENMRLQHEQRAKQGKFYSSK 131 >2L4S-A nrPDB Length = 124 Score = 87.2 bits (214), Expect = 2e-17, Method: Composition-based stats. Identities = 40/109 (36%), Positives = 54/109 (49%), Gaps = 13/109 (11%) Query: 151 RKPPAEKVMEIKLIKGPKG----LGFSIAGGVGNQ-------HIPGDNSIYVTKIIEGGA 199 +P V +++ K +G LGFSI GG+ D IYVT++ EGG Sbjct: 6 GQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGP 65 Query: 200 AHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL-KNTYDVVYLKVAKPS 247 A G LQIGDKI+ VN + V H+ A L K + +VV L V + S Sbjct: 66 AEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQS 113 Score = 81.0 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 38/101 (37%), Positives = 52/101 (51%), Gaps = 11/101 (10%) Query: 61 MEYEEITLERGNSGL--GFSIAGGTD-----NPHIGD--DPSIFITKIIPGGAAAQDGRL 111 ++ EI R L GFSI GG D NP D D I++T++ GG A G L Sbjct: 13 VQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-L 71 Query: 112 RVNDSILFVNEVDVREVTHSAAVEAL-KEAGSIVRLYVMRR 151 ++ D I+ VN D+ VTH A + L K + +VRL V R+ Sbjct: 72 QIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112 Score = 76.4 bits (186), Expect = 4e-14, Method: Composition-based stats. Identities = 35/110 (31%), Positives = 59/110 (53%), Gaps = 24/110 (21%) Query: 307 IPREP-----RRIVIHRGSTG----LGFNIVGGEDGE-------------GIFISFILAG 344 IP +P +R+ IH+ G LGF+I GG D + GI+++ + G Sbjct: 4 IPGQPVTAVVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEG 63 Query: 345 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL-KNAGQTVTIIAQYK 393 GPA+++G L+ GD+I+ VNG D+ +H+QA L K + + V ++ + Sbjct: 64 GPAEIAG-LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 112 >2VZ5-A nrPDB Length = 139 Score = 86.4 bits (212), Expect = 4e-17, Method: Composition-based stats. Identities = 39/102 (38%), Positives = 52/102 (50%), Gaps = 13/102 (12%) Query: 158 VMEIKLIKGPKG----LGFSIAGGVGNQ-------HIPGDNSIYVTKIIEGGAAHKDGRL 206 V +++ K +G LGFSI GG+ D IYVT++ EGG A G L Sbjct: 24 VQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-L 82 Query: 207 QIGDKILAVNSVGLEDVMHEDAVAAL-KNTYDVVYLKVAKPS 247 QIGDKI+ VN + V H+ A L K + +VV L V + S Sbjct: 83 QIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQS 124 Score = 82.6 bits (202), Expect = 6e-16, Method: Composition-based stats. Identities = 38/102 (37%), Positives = 52/102 (50%), Gaps = 11/102 (10%) Query: 60 EMEYEEITLERGNSGL--GFSIAGGTD-----NPHIGD--DPSIFITKIIPGGAAAQDGR 110 ++ EI R L GFSI GG D NP D D I++T++ GG A G Sbjct: 23 MVQRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG- 81 Query: 111 LRVNDSILFVNEVDVREVTHSAAVEAL-KEAGSIVRLYVMRR 151 L++ D I+ VN D+ VTH A + L K + +VRL V R+ Sbjct: 82 LQIGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 123 Score = 76.8 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 32/100 (32%), Positives = 55/100 (55%), Gaps = 19/100 (19%) Query: 312 RRIVIHRGSTG----LGFNIVGGEDGE-------------GIFISFILAGGPADLSGELR 354 +R+ IH+ G LGF+I GG D + GI+++ + GGPA+++G L+ Sbjct: 25 QRVEIHKLRQGENLILGFSIGGGIDQDPSQNPFSEDKTDKGIYVTRVSEGGPAEIAG-LQ 83 Query: 355 KGDQILSVNGVDLRNASHEQAAIAL-KNAGQTVTIIAQYK 393 GD+I+ VNG D+ +H+QA L K + + V ++ + Sbjct: 84 IGDKIMQVNGWDMTMVTHDQARKRLTKRSEEVVRLLVTRQ 123 >1X5N-A nrPDB Length = 114 Score = 85.7 bits (210), Expect = 6e-17, Method: Composition-based stats. Identities = 34/91 (37%), Positives = 49/91 (53%), Gaps = 3/91 (3%) Query: 309 REPRRIVIHRGSTGLGFNIVGGE-DGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 367 +E + + GS GLG +I G GIFIS + G + G L GDQI+ VNGVD Sbjct: 15 KEKKVFISLVGSRGLGCSISSGPIQKPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDF 73 Query: 368 RNASHEQAAIALKNAGQ-TVTIIAQYKPEEY 397 N H++A LK++ T++I+A E + Sbjct: 74 SNLDHKEAVNVLKSSRSLTISIVAAAGRELF 104 Score = 73.3 bits (178), Expect = 3e-13, Method: Composition-based stats. Identities = 28/73 (38%), Positives = 39/73 (53%), Gaps = 6/73 (8%) Query: 71 GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 G+ GLG SI+ G P IFI+ + PG +A+ G L + D I+ VN VD + H Sbjct: 25 GSRGLGCSISSGPIQ-----KPGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSNLDH 78 Query: 131 SAAVEALKEAGSI 143 AV LK + S+ Sbjct: 79 KEAVNVLKSSRSL 91 Score = 63.7 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 26/93 (27%), Positives = 49/93 (52%), Gaps = 7/93 (7%) Query: 166 GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMH 225 G +GLG SI+ G + I+++ + G + + G L+IGD+I+ VN V ++ H Sbjct: 25 GSRGLGCSISSGPIQK-----PGIFISHVKPGSLSAEVG-LEIGDQIVEVNGVDFSNLDH 78 Query: 226 EDAVAALKNTYD-VVYLKVAKPSNAYLSDSYAP 257 ++AV LK++ + + A +++D P Sbjct: 79 KEAVNVLKSSRSLTISIVAAAGRELFMTDRSGP 111 >3CBX-A nrPDB Length = 105 Score = 84.1 bits (206), Expect = 2e-16, Method: Composition-based stats. Identities = 31/84 (36%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV Sbjct: 19 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAV 75 Query: 230 AALKNTY---DVVYLKVAKPSNAY 250 L++ + L VAK + Sbjct: 76 RVLRDIVHKPGPIVLTVAKSGGGW 99 Score = 77.2 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 4/84 (4%) Query: 56 GTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVND 115 G+ + + +E+ N LG SI G ++ D I+I I+ GGA A DGR+ D Sbjct: 1 GSHMNIITVTLNMEKYNF-LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGD 56 Query: 116 SILFVNEVDVREVTHSAAVEALKE 139 +L VN+++ +++ AV L++ Sbjct: 57 MLLQVNDMNFENMSNDDAVRVLRD 80 Score = 68.7 bits (166), Expect = 7e-12, Method: Composition-based stats. Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 323 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L Sbjct: 19 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDMNFENMSNDDAVRVL 78 Query: 380 KN 381 ++ Sbjct: 79 RD 80 >1V5Q-A nrPDB Length = 122 Score = 83.0 bits (203), Expect = 4e-16, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 37/87 (42%), Gaps = 1/87 (1%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 +G G + G P + I+ I A + G L++ D ++ +N + + T Sbjct: 27 TGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEE 85 Query: 133 AVEALKEAGSIVRLYVMRRKPPAEKVM 159 A + L+++ ++ + AE V+ Sbjct: 86 ANQLLRDSSITSKVTLEIEFDVAESVI 112 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Query: 321 TGLGFNIVGGED-----GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQA 375 TG G + G IS+I A PA+ G L+ GD+++++NG+ +++ E+A Sbjct: 27 TGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEA 86 Query: 376 AIALKNAGQTVTIIAQYKPEEY 397 L+++ T + + + + Sbjct: 87 NQLLRDSSITSKVTLEIEFDVA 108 Score = 57.2 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Query: 156 EKVMEIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 + E+ L P G G + G V + ++ I A + G LQIGD+++A Sbjct: 14 TETTEVVLTADPVTGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMA 72 Query: 215 VNSVGLEDVMHEDAVAALKNT 235 +N + ED E+A L+++ Sbjct: 73 INGIPTEDSTFEEANQLLRDS 93 >1N7E-A nrPDB Length = 97 Score = 82.6 bits (202), Expect = 5e-16, Method: Composition-based stats. Identities = 31/92 (33%), Positives = 51/92 (55%), Gaps = 7/92 (7%) Query: 158 VMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS 217 +E+K GP LG +I+G P D I ++ + +GG A + G + IGD+ILA+NS Sbjct: 8 TVELKRYGGP--LGITISG----TEEPFD-PIIISSLTKGGLAERTGAIHIGDRILAINS 60 Query: 218 VGLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 249 L+ +A+ L+ + V LK+ K ++A Sbjct: 61 SSLKGKPLSEAIHLLQMAGETVTLKIKKQTDA 92 Score = 70.3 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 43/90 (47%), Gaps = 5/90 (5%) Query: 64 EEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEV 123 + L+R LG +I+G T+ P I I+ + GG A + G + + D IL +N Sbjct: 7 YTVELKRYGGPLGITISG-TEEPF----DPIIISSLTKGGLAERTGAIHIGDRILAINSS 61 Query: 124 DVREVTHSAAVEALKEAGSIVRLYVMRRKP 153 ++ S A+ L+ AG V L + ++ Sbjct: 62 SLKGKPLSEAIHLLQMAGETVTLKIKKQTD 91 Score = 69.5 bits (168), Expect = 5e-12, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 45/84 (53%), Gaps = 1/84 (1%) Query: 313 RIVIHRGSTGLGFNIVGGEDG-EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNAS 371 + + R LG I G E+ + I IS + GG A+ +G + GD+IL++N L+ Sbjct: 8 TVELKRYGGPLGITISGTEEPFDPIIISSLTKGGLAERTGAIHIGDRILAINSSSLKGKP 67 Query: 372 HEQAAIALKNAGQTVTIIAQYKPE 395 +A L+ AG+TVT+ + + + Sbjct: 68 LSEAIHLLQMAGETVTLKIKKQTD 91 >5GJW-B nrPDB Length = 106 Score = 81.0 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 18/72 (25%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 430 GFYIRALFDYDKTK--DCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 F +R Y+ + + A++F D LH+ + + +WW R V E +GF Sbjct: 34 AFAVRTNVGYNPSPGDEVPVEGVAITFEPKDFLHIKEKYNNDWWIGRLVKEGCE---VGF 90 Query: 488 IPSKRRVERREW 499 IPS +++ Sbjct: 91 IPSPVKLDSLRL 102 >5N7D-A nrPDB Length = 427 Score = 80.7 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 28/101 (27%), Positives = 49/101 (48%), Gaps = 7/101 (6%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 N +E + ++ L + + G GF++ GG + D + I ++ G AA DG++ Sbjct: 11 NPSELKGKFIHTKLRKSSRGFGFTVVGGDE-----PDEFLQIKSLVLDGPAALDGKMETG 65 Query: 115 DSILFVNEVDVREVTHSAAVEALKE--AGSIVRLYVMRRKP 153 D I+ VN+ V TH+ V+ + G+ V L + R P Sbjct: 66 DVIVSVNDTCVLGHTHAQVVKIFQSIPIGASVDLELCRGYP 106 Score = 76.8 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 27/79 (34%), Positives = 40/79 (50%), Gaps = 5/79 (6%) Query: 308 PREPRRIVIH----RGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSV 362 P E + IH + S G GF +VGG E E + I ++ GPA L G++ GD I+SV Sbjct: 12 PSELKGKFIHTKLRKSSRGFGFTVVGGDEPDEFLQIKSLVLDGPAALDGKMETGDVIVSV 71 Query: 363 NGVDLRNASHEQAAIALKN 381 N + +H Q ++ Sbjct: 72 NDTCVLGHTHAQVVKIFQS 90 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 42/92 (45%), Gaps = 7/92 (7%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 K + KL K +G GF++ GG D + + ++ G A DG+++ GD I++VN Sbjct: 18 KFIHTKLRKSSRGFGFTVVGG-----DEPDEFLQIKSLVLDGPAALDGKMETGDVIVSVN 72 Query: 217 SVGLEDVMHEDAVAALKN--TYDVVYLKVAKP 246 + H V ++ V L++ + Sbjct: 73 DTCVLGHTHAQVVKIFQSIPIGASVDLELCRG 104 >1P1E-A nrPDB Length = 101 Score = 80.7 bits (197), Expect = 2e-15, Method: Composition-based stats. Identities = 16/85 (18%), Positives = 35/85 (41%), Gaps = 1/85 (1%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 +G G + G P + I+ I A + G L++ D ++ +N + + T Sbjct: 18 TGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEE 76 Query: 133 AVEALKEAGSIVRLYVMRRKPPAEK 157 A + L+++ ++ + AE Sbjct: 77 ANQLLRDSSITSKVTLEIEFDVAES 101 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 20/82 (24%), Positives = 41/82 (50%), Gaps = 5/82 (6%) Query: 321 TGLGFNIVGGED-----GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQA 375 TG G + G IS+I A PA+ G L+ GD+++++NG+ +++ E+A Sbjct: 18 TGFGIQLQGSVFATETLSSPPLISYIEADSPAERCGVLQIGDRVMAINGIPTEDSTFEEA 77 Query: 376 AIALKNAGQTVTIIAQYKPEEY 397 L+++ T + + + + Sbjct: 78 NQLLRDSSITSKVTLEIEFDVA 99 Score = 57.2 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 38/81 (46%), Gaps = 2/81 (2%) Query: 156 EKVMEIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 + E+ L P G G + G V + ++ I A + G LQIGD+++A Sbjct: 5 TETTEVVLTADPVTGFGIQLQGSVFATETLSSPPL-ISYIEADSPAERCGVLQIGDRVMA 63 Query: 215 VNSVGLEDVMHEDAVAALKNT 235 +N + ED E+A L+++ Sbjct: 64 INGIPTEDSTFEEANQLLRDS 84 >3FY5-A nrPDB Length = 91 Score = 79.1 bits (193), Expect = 6e-15, Method: Composition-based stats. Identities = 27/65 (41%), Positives = 41/65 (63%), Gaps = 3/65 (4%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG SI VG + GD IY+ I++GGA DGR++ GD +L VN + E++ ++DAV Sbjct: 13 LGISI---VGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAV 69 Query: 230 AALKN 234 L++ Sbjct: 70 RVLRD 74 Score = 76.4 bits (186), Expect = 4e-14, Method: Composition-based stats. Identities = 25/77 (32%), Positives = 42/77 (54%), Gaps = 4/77 (5%) Query: 63 YEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNE 122 + +E+ N LG SI G ++ D I+I I+ GGA A DGR+ D +L VN+ Sbjct: 2 TVTLNMEKYNF-LGISIVGQSNER---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVND 57 Query: 123 VDVREVTHSAAVEALKE 139 ++ +++ AV L++ Sbjct: 58 INFENMSNDDAVRVLRD 74 Score = 70.3 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (4%) Query: 323 LGFNIVG--GEDGEG-IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 LG +IVG E G+G I+I I+ GG G + GD +L VN ++ N S++ A L Sbjct: 13 LGISIVGQSNERGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDINFENMSNDDAVRVL 72 Query: 380 KN 381 ++ Sbjct: 73 RD 74 >2MX6-A nrPDB Length = 90 Score = 78.0 bits (190), Expect = 1e-14, Method: Composition-based stats. Identities = 32/84 (38%), Positives = 47/84 (55%), Gaps = 6/84 (7%) Query: 165 KGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVM 224 + LG SI VG + GD IY+ I++GGA DGR++ GD +L VN V E++ Sbjct: 10 ERHHFLGISI---VGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMS 66 Query: 225 HEDAVAALK---NTYDVVYLKVAK 245 ++DAV L+ + + L VAK Sbjct: 67 NDDAVRVLREIVSQTGPISLTVAK 90 Score = 75.7 bits (184), Expect = 7e-14, Method: Composition-based stats. Identities = 27/77 (35%), Positives = 43/77 (55%), Gaps = 4/77 (5%) Query: 63 YEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNE 122 + +ER + LG SI G +++ D I+I I+ GGA A DGR+ D +L VN+ Sbjct: 4 TVTLNMERHHF-LGISIVGQSNDR---GDGGIYIGSIMKGGAVAADGRIEPGDMLLQVND 59 Query: 123 VDVREVTHSAAVEALKE 139 V+ +++ AV L+E Sbjct: 60 VNFENMSNDDAVRVLRE 76 Score = 67.9 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 25/75 (33%), Positives = 37/75 (49%), Gaps = 9/75 (12%) Query: 323 LGFNIVGGEDGEG---IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL 379 LG +IVG + G I+I I+ GG G + GD +L VN V+ N S++ A L Sbjct: 15 LGISIVGQSNDRGDGGIYIGSIMKGGAVAADGRIEPGDMLLQVNDVNFENMSNDDAVRVL 74 Query: 380 KNAGQTVTIIAQYKP 394 + I++Q P Sbjct: 75 R------EIVSQTGP 83 >5G1D-A nrPDB Length = 201 Score = 77.2 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 39/192 (20%), Positives = 71/192 (36%), Gaps = 29/192 (15%) Query: 56 GTEGEMEYEEITLERGNSG-LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 G E + E+ L + G +G + D IF+ + A+ G LR Sbjct: 8 GAEIKQGIREVILCKDQDGKIGLRLK--------SVDNGIFVQLVQANSPASLVG-LRFG 58 Query: 115 DSILFVNEVDVREVTHSAAVEALKEA-GSIVRLYVMRRKPPAEKVMEIKLIKGPKG-LGF 172 D +L +N + + A + LK+A G + + + R P E+ + + K G +GF Sbjct: 59 DQVLQINGENCAGWSSDKAHKVLKQAFGEKITMTIRDR--PFERT--VTMHKDSSGHVGF 114 Query: 173 SIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL 232 G +T I++ +A ++G L I +N + + L Sbjct: 115 IFKSGK------------ITSIVKDSSAARNGLL-TDHHICEINGQNVIGLKDAQIADIL 161 Query: 233 KNTYDVVYLKVA 244 VV + + Sbjct: 162 STAGTVVTITIM 173 Score = 68.3 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 29/93 (31%), Positives = 51/93 (54%), Gaps = 5/93 (5%) Query: 306 DIPREPRRIVIHRGSTG-LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNG 364 +I + R +++ + G +G + ++ GIF+ + A PA L G LR GDQ+L +NG Sbjct: 10 EIKQGIREVILCKDQDGKIGLRLKSVDN--GIFVQLVQANSPASLVG-LRFGDQVLQING 66 Query: 365 VDLRNASHEQAAIALKNA-GQTVTIIAQYKPEE 396 + S ++A LK A G+ +T+ + +P E Sbjct: 67 ENCAGWSSDKAHKVLKQAFGEKITMTIRDRPFE 99 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 32/117 (27%), Positives = 47/117 (40%), Gaps = 13/117 (11%) Query: 299 KDLLGEEDIPREPRRIVIHRGSTG-LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGD 357 K + D P E R + +H+ S+G +GF G+ I+ I+ A +G L Sbjct: 88 KITMTIRDRPFE-RTVTMHKDSSGHVGFIFKSGK------ITSIVKDSSAARNGLL-TDH 139 Query: 358 QILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNS 414 I +NG ++ Q A L AG VTI FE I + +M S Sbjct: 140 HICEINGQNVIGLKDAQIADILSTAGTVVTITIM----PAFIFEHIIKRMAPSIMKS 192 >5A2P-A nrPDB Length = 163 Score = 76.8 bits (187), Expect = 3e-14, Method: Composition-based stats. Identities = 34/166 (20%), Positives = 61/166 (36%), Gaps = 20/166 (12%) Query: 81 GGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEA 140 G D IF+ + A+ G LR D +L +N + + A + LK+A Sbjct: 14 GKIGLRLKSVDNGIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGWSSDKAHKVLKQA 72 Query: 141 -GSIVRLYVMRRKPPAEKVMEIKLIKGPKG-LGFSIAGGVGNQHIPGDNSIYVTKIIEGG 198 G + + + R P E+ + + K G +GF G +T I++ Sbjct: 73 FGEKITMTIRDR--PFERT--VTMHKDSSGHVGFIFKSGK------------ITSIVKDS 116 Query: 199 AAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVA 244 +A ++G L I +N + + L VV + + Sbjct: 117 SAARNGLL-TDHHICEINGQNVIGLKDAQIADILSTAGTVVTITIM 161 Score = 67.9 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 28/87 (32%), Positives = 48/87 (55%), Gaps = 5/87 (5%) Query: 312 RRIVIHRGSTG-LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 R +++ + G +G + ++ GIF+ + A PA L G LR GDQ+L +NG + Sbjct: 4 REVILCKDQDGKIGLRLKSVDN--GIFVQLVQANSPASLVG-LRFGDQVLQINGENCAGW 60 Query: 371 SHEQAAIALKNA-GQTVTIIAQYKPEE 396 S ++A LK A G+ +T+ + +P E Sbjct: 61 SSDKAHKVLKQAFGEKITMTIRDRPFE 87 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 27/93 (29%), Positives = 40/93 (43%), Gaps = 9/93 (9%) Query: 299 KDLLGEEDIPREPRRIVIHRGSTG-LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGD 357 K + D P E R + +H+ S+G +GF G+ I+ I+ A +G L Sbjct: 76 KITMTIRDRPFE-RTVTMHKDSSGHVGFIFKSGK------ITSIVKDSSAARNGLL-TDH 127 Query: 358 QILSVNGVDLRNASHEQAAIALKNAGQTVTIIA 390 I +NG ++ Q A L AG VTI Sbjct: 128 HICEINGQNVIGLKDAQIADILSTAGTVVTITI 160 >1UEW-A nrPDB Length = 114 Score = 76.4 bits (186), Expect = 4e-14, Method: Composition-based stats. Identities = 32/84 (38%), Positives = 44/84 (52%), Gaps = 9/84 (10%) Query: 314 IVIHRGST-GLGFNIVGG----EDGEGIF----ISFILAGGPADLSGELRKGDQILSVNG 364 +VIHR G GF I+ E G I I I+ G PAD +L+ GD+IL+VNG Sbjct: 14 VVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNG 73 Query: 365 VDLRNASHEQAAIALKNAGQTVTI 388 + N H +K+AG +VT+ Sbjct: 74 QSIINMPHADIVKLIKDAGLSVTL 97 Score = 74.9 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 3/92 (3%) Query: 61 MEYEEITLER-GNSGLGFSIAGGTDNPHIGDDPSI--FITKIIPGGAAAQDGRLRVNDSI 117 ++ ++ + R N G GF I + P G ++ I +II G A + +L+V D I Sbjct: 9 LQTSDVVIHRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRI 68 Query: 118 LFVNEVDVREVTHSAAVEALKEAGSIVRLYVM 149 L VN + + H+ V+ +K+AG V L ++ Sbjct: 69 LAVNGQSIINMPHADIVKLIKDAGLSVTLRII 100 Score = 67.9 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 23/86 (26%), Positives = 42/86 (48%), Gaps = 2/86 (2%) Query: 163 LIKGPKGLGFSIAGGVGNQHIPGDNSI--YVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 K +G GF I + ++ + +II+G A + +L++GD+ILAVN + Sbjct: 17 HRKENEGFGFVIISSLNRPESGSTITVPHKIGRIIDGSPADRCAKLKVGDRILAVNGQSI 76 Query: 221 EDVMHEDAVAALKNTYDVVYLKVAKP 246 ++ H D V +K+ V L++ Sbjct: 77 INMPHADIVKLIKDAGLSVTLRIIPQ 102 >1UF1-A nrPDB Length = 128 Score = 75.3 bits (183), Expect = 8e-14, Method: Composition-based stats. Identities = 30/91 (32%), Positives = 46/91 (50%), Gaps = 2/91 (2%) Query: 310 EPRRIVIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 E + ++ LG I GG E G GI+I+ + G A+ SG L+ GDQIL VNG Sbjct: 21 EKKVNLVLGDGRSLGLTIRGGAEYGLGIYITGVDPGSEAEGSG-LKVGDQILEVNGRSFL 79 Query: 369 NASHEQAAIALKNAGQTVTIIAQYKPEEYSR 399 N H++A LK++ + + ++R Sbjct: 80 NILHDEAVRLLKSSRHLILTVKDVGRLPHAR 110 Score = 67.6 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 6/88 (6%) Query: 71 GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 LG +I GG + I+IT + PG A G L+V D IL VN + H Sbjct: 30 DGRSLGLTIRGGAEY-----GLGIYITGVDPGSEAEGSG-LKVGDQILEVNGRSFLNILH 83 Query: 131 SAAVEALKEAGSIVRLYVMRRKPPAEKV 158 AV LK + ++ + P + Sbjct: 84 DEAVRLLKSSRHLILTVKDVGRLPHART 111 Score = 66.4 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 39/74 (52%), Gaps = 6/74 (8%) Query: 166 GPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMH 225 + LG +I GG IY+T + G A G L++GD+IL VN +++H Sbjct: 30 DGRSLGLTIRGGA-----EYGLGIYITGVDPGSEAEGSG-LKVGDQILEVNGRSFLNILH 83 Query: 226 EDAVAALKNTYDVV 239 ++AV LK++ ++ Sbjct: 84 DEAVRLLKSSRHLI 97 >4QL6-A nrPDB Length = 634 Score = 74.9 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 29/84 (34%), Positives = 46/84 (54%), Gaps = 3/84 (3%) Query: 311 PRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 R + +G G+G +V ED +G+ + +LAGGPAD +G LR GD I VNG ++ N Sbjct: 227 SMRAQLEKGMCGIG--VVLKEDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIENT 284 Query: 371 SHEQAAIALKNA-GQTVTIIAQYK 393 +L+ + G +VT+ + Sbjct: 285 PFPGVLDSLRGSPGSSVTLDIHRQ 308 Score = 56.8 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 66/180 (36%), Gaps = 15/180 (8%) Query: 177 GVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNT- 235 G+G + + V +++ GG A K G L++GD I VN +E+ + +L+ + Sbjct: 238 GIGVVLKEDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIENTPFPGVLDSLRGSP 297 Query: 236 YDVVYLKVAKPSNAYLSDSY------APPDITTSYSQH----LDNEISHSSYLGTDYPTA 285 V L + + +N ++ + SY + + HS Y G + ++ Sbjct: 298 GSSVTLDIHRQNNDHVIQLRREKILLDSRRVDVSYEPYGNGIIGKITLHSFYEGENQVSS 357 Query: 286 MTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGG 345 K+LLG RE + + G + G + +S G Sbjct: 358 EQDLRKAIRELQEKNLLGLVLDIRENTGGFLSQAIKVSGLFLTNGV----VVVSRYADGS 413 Score = 56.0 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 25/99 (25%), Positives = 48/99 (48%), Gaps = 11/99 (11%) Query: 68 LERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 LE+G G+G + D + + +++ GG A + G LRV D I VN ++ Sbjct: 232 LEKGMCGIGVVLK--------EDIDGVVVKEVLAGGPADKTGSLRVGDIIYRVNGKNIEN 283 Query: 128 VTHSAAVEALKEA-GSIVRLYVMRRKPPAEKVMEIKLIK 165 +++L+ + GS V L + R+ + V++++ K Sbjct: 284 TPFPGVLDSLRGSPGSSVTLDIHRQN--NDHVIQLRREK 320 >1U37-A nrPDB Length = 89 Score = 73.3 bits (178), Expect = 4e-13, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 47/93 (50%), Gaps = 8/93 (8%) Query: 62 EYEEITLER-GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 E++++ +E+ LG I ++ P++ I ++ GG A + G+L + D I+ + Sbjct: 1 EFKDVFIEKQKGEILGVVI---VESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSI 57 Query: 121 NEVDVREV---THSAAVEALKEAGSIVRLYVMR 150 N + + T + ++ LK S V+L ++R Sbjct: 58 NGTSLVGLPLSTCQSIIKGLKN-QSRVKLNIVR 89 Score = 52.2 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 15/59 (25%), Positives = 30/59 (50%), Gaps = 2/59 (3%) Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYD--VVYLKVAK 245 + + ++ GG A K G+L IGD+I+++N L + + +K + V L + + Sbjct: 31 VIIANMMHGGPAEKSGKLNIGDQIMSINGTSLVGLPLSTCQSIIKGLKNQSRVKLNIVR 89 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 24/83 (28%), Positives = 37/83 (44%), Gaps = 4/83 (4%) Query: 310 EPRRIVIHR-GSTGLGFNIVG---GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV 365 E + + I + LG IV G + I+ ++ GGPA+ SG+L GDQI+S+NG Sbjct: 1 EFKDVFIEKQKGEILGVVIVESGWGSILPTVIIANMMHGGPAEKSGKLNIGDQIMSINGT 60 Query: 366 DLRNASHEQAAIALKNAGQTVTI 388 L +K + Sbjct: 61 SLVGLPLSTCQSIIKGLKNQSRV 83 >1X5R-A nrPDB Length = 112 Score = 73.0 bits (177), Expect = 4e-13, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 34/81 (41%), Gaps = 1/81 (1%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 SG G + GG P + + I P A + G L+V D +L +N + + T Sbjct: 27 SGFGLQLQGGIFATETLSSPPL-VCFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEE 85 Query: 133 AVEALKEAGSIVRLYVMRRKP 153 A + L++A ++ + Sbjct: 86 ANQLLRDAALAHKVVLEVEFD 106 Score = 64.5 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 37/81 (45%), Gaps = 2/81 (2%) Query: 156 EKVMEIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 + E+ L P G G + GG+ + V I A + G LQ+GD++L+ Sbjct: 14 TETTEVVLCGDPLSGFGLQLQGGIFATETLSSPPL-VCFIEPDSPAERCGLLQVGDRVLS 72 Query: 215 VNSVGLEDVMHEDAVAALKNT 235 +N + ED E+A L++ Sbjct: 73 INGIATEDGTMEEANQLLRDA 93 Score = 61.4 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 5/76 (6%) Query: 321 TGLGFNIVGGED-----GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQA 375 +G G + GG + FI PA+ G L+ GD++LS+NG+ + + E+A Sbjct: 27 SGFGLQLQGGIFATETLSSPPLVCFIEPDSPAERCGLLQVGDRVLSINGIATEDGTMEEA 86 Query: 376 AIALKNAGQTVTIIAQ 391 L++A ++ + Sbjct: 87 NQLLRDAALAHKVVLE 102 >3QDO-A nrPDB Length = 109 Score = 72.2 bits (175), Expect = 7e-13, Method: Composition-based stats. Identities = 29/95 (30%), Positives = 47/95 (49%), Gaps = 14/95 (14%) Query: 309 REPRRIVIHRGSTGLGFNIVGGEDGEGIF-------------ISFILAGGPADLSGELRK 355 PR + I + +G GFN+ G G +S +L GG AD +G +RK Sbjct: 5 GSPRVVRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRK 63 Query: 356 GDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIA 390 GD+IL VNGV++ A+H+Q ++ + + + Sbjct: 64 GDRILEVNGVNVEGATHKQVVDLIRAGEKELILTV 98 Score = 63.7 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 25/91 (27%), Positives = 42/91 (46%), Gaps = 8/91 (8%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDD-------PSIFITKIIPGGAAAQDGRLRVNDSIL 118 + + + SG GF++ G P ++ ++PGGAA + G +R D IL Sbjct: 10 VRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGDRIL 68 Query: 119 FVNEVDVREVTHSAAVEALKEAGSIVRLYVM 149 VN V+V TH V+ ++ + L V+ Sbjct: 69 EVNGVNVEGATHKQVVDLIRAGEKELILTVL 99 Score = 61.8 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 27/95 (28%), Positives = 47/95 (49%), Gaps = 8/95 (8%) Query: 161 IKLIKGPKGLGFSIAGGV--GNQHIPGDNSIY-----VTKIIEGGAAHKDGRLQIGDKIL 213 ++++K G GF++ G V G Q + +Y V+ ++ GGAA + G ++ GD+IL Sbjct: 10 VRIVKSESGYGFNVRGQVSEGGQLRSINGELYAPLQHVSAVLPGGAADRAG-VRKGDRIL 68 Query: 214 AVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSN 248 VN V +E H+ V ++ + L V Sbjct: 69 EVNGVNVEGATHKQVVDLIRAGEKELILTVLSVGG 103 >1U39-A nrPDB Length = 80 Score = 71.4 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 38/91 (41%), Gaps = 13/91 (14%) Query: 154 PAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKIL 213 P + I+ LGFS+ G+ + ++ GG A + G +++G +I+ Sbjct: 1 PPVTTVLIRRPDLRYQLGFSVQNGI------------ICSLMRGGIAERGG-VRVGHRII 47 Query: 214 AVNSVGLEDVMHEDAVAALKNTYDVVYLKVA 244 +N + HE V L N +++K Sbjct: 48 EINGQSVVATPHEKIVHILSNAVGEIHMKTM 78 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 7/66 (10%) Query: 323 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 382 LGF++ G I ++ GG A+ G +R G +I+ +NG + HE+ L NA Sbjct: 17 LGFSVQNG------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATPHEKIVHILSNA 69 Query: 383 GQTVTI 388 + + Sbjct: 70 VGEIHM 75 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 26/66 (39%), Gaps = 13/66 (19%) Query: 75 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 134 LGFS+ G I ++ GG A + G +RV I+ +N V H V Sbjct: 17 LGFSVQNG------------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATPHEKIV 63 Query: 135 EALKEA 140 L A Sbjct: 64 HILSNA 69 >1UJD-A nrPDB Length = 117 Score = 70.6 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 24/81 (29%), Positives = 40/81 (49%), Gaps = 6/81 (7%) Query: 319 GSTGLGFNIVGGEDGEG------IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 GLG IVGG++ G +I+ IL GG A+ +G+L +G Q+L NG+ L + ++ Sbjct: 28 SGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTY 87 Query: 373 EQAAIALKNAGQTVTIIAQYK 393 E+ + I + Sbjct: 88 EEVQSIISQQSGEAEICVRLD 108 Score = 66.4 bits (160), Expect = 4e-11, Method: Composition-based stats. Identities = 21/79 (26%), Positives = 35/79 (44%) Query: 71 GNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 +GLG I GG + P + +I KI+PGG+A Q G+L +L N + + T+ Sbjct: 28 SGNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTY 87 Query: 131 SAAVEALKEAGSIVRLYVM 149 + + + V Sbjct: 88 EEVQSIISQQSGEAEICVR 106 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 35/78 (44%) Query: 167 PKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHE 226 GLG I GG G+ Y+ KI+ GG+A + G+L G ++L N + L +E Sbjct: 29 GNGLGIRIVGGKEIPGHSGEIGAYIAKILPGGSAEQTGKLMEGMQVLEWNGIPLTSKTYE 88 Query: 227 DAVAALKNTYDVVYLKVA 244 + + + + V Sbjct: 89 EVQSIISQQSGEAEICVR 106 >1Y7N-A nrPDB Length = 90 Score = 70.3 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 16/85 (18%) Query: 163 LIKGPK---GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG 219 LI+ P LGFS+ G+ + ++ GG A + G +++G +I+ +N Sbjct: 16 LIRRPDLRYQLGFSVQNGI------------ICSLMRGGIAERGG-VRVGHRIIEINGQS 62 Query: 220 LEDVMHEDAVAALKNTYDVVYLKVA 244 + HE V L N +++K Sbjct: 63 VVATPHEKIVHILSNAVGEIHMKTM 87 Score = 45.6 bits (106), Expect = 7e-05, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 30/84 (35%), Gaps = 13/84 (15%) Query: 57 TEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDS 116 T G + I LGFS+ G I ++ GG A + G +RV Sbjct: 8 TMGNVTTVLIRRPDLRYQLGFSVQNG------------IICSLMRGGIAER-GGVRVGHR 54 Query: 117 ILFVNEVDVREVTHSAAVEALKEA 140 I+ +N V H V L A Sbjct: 55 IIEINGQSVVATPHEKIVHILSNA 78 Score = 45.6 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 32/66 (48%), Gaps = 7/66 (10%) Query: 323 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 382 LGF++ G I ++ GG A+ G +R G +I+ +NG + HE+ L NA Sbjct: 26 LGFSVQNG------IICSLMRGGIAER-GGVRVGHRIIEINGQSVVATPHEKIVHILSNA 78 Query: 383 GQTVTI 388 + + Sbjct: 79 VGEIHM 84 >1GRI-A nrPDB Length = 217 Score = 67.2 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 19/47 (40%), Positives = 28/47 (59%), Gaps = 5/47 (10%) Query: 427 PKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 P++ Y++ALFD+D +D L FR GD +HV+D D WW+ Sbjct: 155 PQQPTYVQALFDFDPQED-----GELGFRRGDFIHVMDNSDPNWWKG 196 Score = 35.2 bits (79), Expect = 0.12, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 32/86 (37%), Gaps = 12/86 (13%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAG-DEEWWQARRVHSDSETDDIGFIPSKRR 493 A +D+ T D LSF+ GD+L V++ D+ W++A D GFIP Sbjct: 5 AKYDFKATAD-----DELSFKRGDILKVLNEECDQNWYKAELNGKD------GFIPKNYI 53 Query: 494 VERREWSRLKAKDWGSSSGSQGREDS 519 + + ++ Sbjct: 54 EMKPHPWFFGKIPRAKAEEMLSKQRH 79 >2LC7-A nrPDB Length = 102 Score = 65.3 bits (157), Expect = 9e-11, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 62 EYEEITLERGNSGLGFSIAGGTDNPHIGDD----PSIFITKIIPGGAAAQDGRLRVNDSI 117 + + LGF I GT P IFI++++PGG A G L VND + Sbjct: 6 RRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEV 65 Query: 118 LFVNEVDVREVTHSAAVEAL 137 + VN ++V T + + Sbjct: 66 IEVNGIEVAGKTLDQVTDMM 85 Score = 60.6 bits (145), Expect = 2e-09, Method: Composition-based stats. Identities = 24/89 (26%), Positives = 41/89 (46%), Gaps = 10/89 (11%) Query: 313 RIVIHRGSTGLGFNIVGG----------EDGEGIFISFILAGGPADLSGELRKGDQILSV 362 R++ H LGF I G E GIFIS ++ GG A+ +G L D+++ V Sbjct: 9 RLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEV 68 Query: 363 NGVDLRNASHEQAAIALKNAGQTVTIIAQ 391 NG+++ + +Q + + I + Sbjct: 69 NGIEVAGKTLDQVTDMMVANSSNLIITVK 97 Score = 54.1 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 155 AEKVMEIKLIKGP--KGLGFSIAGG----VGNQHIPGDNSIYVTKIIEGGAAHKDGRLQI 208 +E ++L+K K LGF I G V + I++++++ GG A G L + Sbjct: 2 SETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAV 61 Query: 209 GDKILAVNSVGLEDVMHEDAVAAL 232 D+++ VN + + + + Sbjct: 62 NDEVIEVNGIEVAGKTLDQVTDMM 85 >1RY4-A nrPDB Length = 128 Score = 64.9 bits (156), Expect = 1e-10, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 35/80 (43%), Gaps = 4/80 (5%) Query: 62 EYEEITLERGNSGLGFSIAGGTDNPHIGDD----PSIFITKIIPGGAAAQDGRLRVNDSI 117 + + LGF I GT P IFI++++PGG A G L VND + Sbjct: 32 RRVRLLKHGSDKPLGFYIRDGTSVRVTASGLEKQPGIFISRLVPGGLAESTGLLAVNDEV 91 Query: 118 LFVNEVDVREVTHSAAVEAL 137 + VN ++V T + + Sbjct: 92 IEVNGIEVAGKTLDQVTDMM 111 Score = 62.6 bits (150), Expect = 6e-10, Method: Composition-based stats. Identities = 30/124 (24%), Positives = 54/124 (43%), Gaps = 16/124 (12%) Query: 280 TDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTG--LGFNIVGG------- 330 T P+ P R+ S + + +P RR+ + + + LGF I G Sbjct: 4 TKAPSISIPHDFRQVSAIIDV----DIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTA 59 Query: 331 ---EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVT 387 E GIFIS ++ GG A+ +G L D+++ VNG+++ + +Q + + Sbjct: 60 SGLEKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMMVANSSNLI 119 Query: 388 IIAQ 391 I + Sbjct: 120 ITVK 123 Score = 58.7 bits (140), Expect = 8e-09, Method: Composition-based stats. Identities = 18/109 (16%), Positives = 43/109 (39%), Gaps = 4/109 (3%) Query: 128 VTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGG----VGNQHI 183 T + ++ + + + + P + + + K LGF I G V + Sbjct: 3 KTKAPSISIPHDFRQVSAIIDVDIVPETHRRVRLLKHGSDKPLGFYIRDGTSVRVTASGL 62 Query: 184 PGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL 232 I++++++ GG A G L + D+++ VN + + + + Sbjct: 63 EKQPGIFISRLVPGGLAESTGLLAVNDEVIEVNGIEVAGKTLDQVTDMM 111 >1UFX-A nrPDB Length = 103 Score = 64.1 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 5/85 (5%) Query: 56 GTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVND 115 G+ G + +++ + LG +I GG + P I I GG+A G+L+V Sbjct: 1 GSSGSSGTL-VRVKKSAATLGIAIEGGANTRQ----PLPRIVTIQRGGSAHNCGQLKVGH 55 Query: 116 SILFVNEVDVREVTHSAAVEALKEA 140 IL VN + +R H A + EA Sbjct: 56 VILEVNGLTLRGKEHREAARIIAEA 80 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 35/78 (44%), Gaps = 4/78 (5%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 +++ K LG +I GG + + I GG+AH G+L++G IL VN + L Sbjct: 10 VRVKKSAATLGIAIEGGANTRQPLP----RIVTIQRGGSAHNCGQLKVGHVILEVNGLTL 65 Query: 221 EDVMHEDAVAALKNTYDV 238 H +A + + Sbjct: 66 RGKEHREAARIIAEAFKT 83 Score = 54.1 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 25/74 (33%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 314 IVIHRGSTGLGFNIVGGEDGEGIF--ISFILAGGPADLSGELRKGDQILSVNGVDLRNAS 371 + + + + LG I GG + I I GG A G+L+ G IL VNG+ LR Sbjct: 10 VRVKKSAATLGIAIEGGANTRQPLPRIVTIQRGGSAHNCGQLKVGHVILEVNGLTLRGKE 69 Query: 372 HEQAAIALKNAGQT 385 H +AA + A +T Sbjct: 70 HREAARIIAEAFKT 83 >4UU6-A nrPDB Length = 90 Score = 63.7 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Query: 312 RRIVIHRGST-GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 + + I + LG + + + + IS I+ GG A+ SG L +GD++L +NG+++R Sbjct: 10 KIVRIEKARDIPLGATVR--NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 67 Query: 371 SHEQAAIALKNAGQTVTIIA 390 + L + T+T + Sbjct: 68 DVNEVFDLLSDMHGTLTFVL 87 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 14/58 (24%), Positives = 30/58 (51%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVM 149 S+ I++I+ GGAA + G L D +L +N +++R + + L + + ++ Sbjct: 31 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLI 88 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 19/89 (21%), Positives = 41/89 (46%), Gaps = 9/89 (10%) Query: 156 EKVMEIKLIKGPK-GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 E V +++ K LG ++ + S+ +++I++GGAA K G L GD++L Sbjct: 7 ETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAAEKSGLLHEGDEVLE 58 Query: 215 VNSVGLEDVMHEDAVAALKNTYDVVYLKV 243 +N + + + L + + + + Sbjct: 59 INGIEIRGKDVNEVFDLLSDMHGTLTFVL 87 >2DLS-A nrPDB Length = 93 Score = 63.7 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 24/95 (25%), Positives = 47/95 (49%), Gaps = 12/95 (12%) Query: 56 GTEGEMEYEE-ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 G+ G + + +++ G GF+++G D + + + PGGAA + G ++ Sbjct: 1 GSSGSSGVQRCVIIQKDQHGFGFTVSG---------DRIVLVQSVRPGGAAMKAG-VKEG 50 Query: 115 DSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVM 149 D I+ VN V +H V+ +K +G+ V L ++ Sbjct: 51 DRIIKVNGTMVTNSSHLEVVKLIK-SGAYVALTLL 84 Score = 62.2 bits (149), Expect = 9e-10, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 42/88 (47%), Gaps = 5/88 (5%) Query: 303 GEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSV 362 G R ++I + G GF + G + + + GG A +G +++GD+I+ V Sbjct: 1 GSSGSSGVQRCVIIQKDQHGFGFTVSG---DRIVLVQSVRPGGAAMKAG-VKEGDRIIKV 56 Query: 363 NGVDLRNASHEQAAIALKNAGQTVTIIA 390 NG + N+SH + +K +G V + Sbjct: 57 NGTMVTNSSHLEVVKLIK-SGAYVALTL 83 Score = 54.9 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 10/73 (13%) Query: 163 LIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 + K G GF+++G D + V + GGAA K G ++ GD+I+ VN + + Sbjct: 14 IQKDQHGFGFTVSG---------DRIVLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTN 63 Query: 223 VMHEDAVAALKNT 235 H + V +K+ Sbjct: 64 SSHLEVVKLIKSG 76 >1VA8-A nrPDB Length = 113 Score = 62.9 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 41/80 (51%), Gaps = 3/80 (3%) Query: 312 RRIVIHRGST-GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 + + I + LG + + + + IS I+ GG A+ SG L +GD++L +NG+++R Sbjct: 27 KIVRIEKARDIPLGATVR--NEMDSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGK 84 Query: 371 SHEQAAIALKNAGQTVTIIA 390 + L + T+T + Sbjct: 85 DVNEVFDLLSDMHGTLTFVL 104 Score = 52.2 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 42/94 (44%), Gaps = 9/94 (9%) Query: 156 EKVMEIKLIKGPK-GLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILA 214 E V +++ K LG ++ + S+ +++I++GGAA K G L GD++L Sbjct: 24 ETVKIVRIEKARDIPLGATVRNEMD--------SVIISRIVKGGAAEKSGLLHEGDEVLE 75 Query: 215 VNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSN 248 +N + + + L + + + + S Sbjct: 76 INGIEIRGKDVNEVFDLLSDMHGTLTFVLIPSSG 109 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 32/65 (49%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 S+ I++I+ GGAA + G L D +L +N +++R + + L + + ++ Sbjct: 48 DSVIISRIVKGGAAEKSGLLHEGDEVLEINGIEIRGKDVNEVFDLLSDMHGTLTFVLIPS 107 Query: 152 KPPAE 156 P+ Sbjct: 108 SGPSS 112 >5E6P-B nrPDB Length = 88 Score = 62.2 bits (149), Expect = 8e-10, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 40/85 (47%), Gaps = 4/85 (4%) Query: 311 PRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 R ++I + G GF + G + + + GG A +G +++GD+I+ VNG + N+ Sbjct: 8 QRCVIIQKDQHGFGFTVSG---DRIVLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTNS 63 Query: 371 SHEQAAIALKNAGQTVTIIAQYKPE 395 SH + +K+ + P Sbjct: 64 SHLEVVKLIKSGAYVALTLLGSSPS 88 Score = 61.8 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 23/88 (26%), Positives = 44/88 (50%), Gaps = 11/88 (12%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + +++ G GF+++G D + + + PGGAA + G ++ D I+ VN V Sbjct: 11 VIIQKDQHGFGFTVSG---------DRIVLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMV 60 Query: 126 REVTHSAAVEALKEAGSIVRLYVMRRKP 153 +H V+ +K +G+ V L ++ P Sbjct: 61 TNSSHLEVVKLIK-SGAYVALTLLGSSP 87 Score = 54.9 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 21/73 (28%), Positives = 36/73 (49%), Gaps = 10/73 (13%) Query: 163 LIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 + K G GF+++G D + V + GGAA K G ++ GD+I+ VN + + Sbjct: 13 IQKDQHGFGFTVSG---------DRIVLVQSVRPGGAAMKAG-VKEGDRIIKVNGTMVTN 62 Query: 223 VMHEDAVAALKNT 235 H + V +K+ Sbjct: 63 SSHLEVVKLIKSG 75 >2YT8-A nrPDB Length = 94 Score = 62.2 bits (149), Expect = 8e-10, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 33/78 (42%), Gaps = 13/78 (16%) Query: 167 PKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHE 226 + LGF + G+ + ++ GG A + G +++G +I+ +N + H Sbjct: 19 REQLGFCVEDGI------------ICSLLRGGIAERGG-IRVGHRIIEINGQSVVATPHA 65 Query: 227 DAVAALKNTYDVVYLKVA 244 + L Y V++K Sbjct: 66 RIIELLTEAYGEVHIKTM 83 Score = 49.1 bits (115), Expect = 6e-06, Method: Composition-based stats. Identities = 23/93 (24%), Positives = 36/93 (38%), Gaps = 15/93 (16%) Query: 56 GTEGEMEYEEITLERGN--SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRV 113 G+ G + R + LGF + G I ++ GG A + G +RV Sbjct: 1 GSSGSSGVTTAIIHRPHAREQLGFCVEDG------------IICSLLRGGIAER-GGIRV 47 Query: 114 NDSILFVNEVDVREVTHSAAVEALKEAGSIVRL 146 I+ +N V H+ +E L EA V + Sbjct: 48 GHRIIEINGQSVVATPHARIIELLTEAYGEVHI 80 Score = 45.2 bits (105), Expect = 9e-05, Method: Composition-based stats. Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 9/78 (11%) Query: 313 RIVIHR--GSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA 370 +IHR LGF + G I +L GG A+ G +R G +I+ +NG + Sbjct: 10 TAIIHRPHAREQLGFCVEDG------IICSLLRGGIAER-GGIRVGHRIIEINGQSVVAT 62 Query: 371 SHEQAAIALKNAGQTVTI 388 H + L A V I Sbjct: 63 PHARIIELLTEAYGEVHI 80 >1NF3-C nrPDB Length = 128 Score = 61.8 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 24/67 (35%), Positives = 36/67 (53%), Gaps = 4/67 (5%) Query: 75 LGFSIAGGTD---NPHIGDD-PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH 130 LGF I G+ PH + P IFI++++PGG A G L VND +L VN ++V + Sbjct: 44 LGFYIRDGSSVRVTPHGLEKVPGIFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSL 103 Query: 131 SAAVEAL 137 + + Sbjct: 104 DQVTDMM 110 Score = 60.2 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 31/115 (26%), Positives = 55/115 (47%), Gaps = 13/115 (11%) Query: 289 TSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTG--LGFNIVGG----------EDGEGI 336 + P+ + PV+ ++ + +P RR+ + + T LGF I G E GI Sbjct: 9 SMPQDFRPVSS-IIDVDILPETHRRVRLCKYGTEKPLGFYIRDGSSVRVTPHGLEKVPGI 67 Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQ 391 FIS ++ GG A +G L D++L VNG+++ S +Q + + + I + Sbjct: 68 FISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMMIANSRNLIITVR 122 Score = 54.5 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 18/104 (17%), Positives = 41/104 (39%), Gaps = 4/104 (3%) Query: 133 AVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDN----S 188 + ++ + + + P + + + K LGF I G + P Sbjct: 7 VISMPQDFRPVSSIIDVDILPETHRRVRLCKYGTEKPLGFYIRDGSSVRVTPHGLEKVPG 66 Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAAL 232 I++++++ GG A G L + D++L VN + + + + Sbjct: 67 IFISRLVPGGLAQSTGLLAVNDEVLEVNGIEVSGKSLDQVTDMM 110 >2YT7-A nrPDB Length = 101 Score = 61.4 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 27/105 (25%), Positives = 46/105 (43%), Gaps = 10/105 (9%) Query: 55 NGTEGEMEYEEITLE-RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRV 113 +G+ G+ E+ LE R GLG ++ ++ P+ I ++ GG A + G L + Sbjct: 3 SGSSGD-NCREVHLEKRRGEGLGVAL---VESGWGSLLPTAVIANLLHGGPAERSGALSI 58 Query: 114 NDSILFVNEVDVREV---THSAAVEALKEAGSIVRLYVMRRKPPA 155 D + +N + + AAV K S V L ++ PP Sbjct: 59 GDRLTAINGTSLVGLPLAACQAAVRETKSQTS-VTLSIVH-CPPV 101 Score = 51.8 bits (122), Expect = 9e-07, Method: Composition-based stats. Identities = 24/100 (24%), Positives = 41/100 (41%), Gaps = 12/100 (12%) Query: 160 EIKLIKGP-KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 E+ L K +GLG ++ +P + ++ GG A + G L IGD++ A+N Sbjct: 12 EVHLEKRRGEGLGVALVESGWGSLLPTA---VIANLLHGGPAERSGALSIGDRLTAINGT 68 Query: 219 GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPP 258 L + L V + ++ LS + PP Sbjct: 69 SLVGLP-------LAACQAAVR-ETKSQTSVTLSIVHCPP 100 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 39/84 (46%), Gaps = 5/84 (5%) Query: 318 RGSTGLGFNIVG---GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE- 373 R GLG +V G I+ +L GGPA+ SG L GD++ ++NG L Sbjct: 18 RRGEGLGVALVESGWGSLLPTAVIANLLHGGPAERSGALSIGDRLTAINGTSLVGLPLAA 77 Query: 374 -QAAIALKNAGQTVTIIAQYKPEE 396 QAA+ + +VT+ + P Sbjct: 78 CQAAVRETKSQTSVTLSIVHCPPV 101 >1GCQ-A nrPDB Length = 61 Score = 61.4 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 18/44 (40%), Positives = 25/44 (56%), Gaps = 5/44 (11%) Query: 430 GFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 Y++ALFD+D +D L FR GD +HV+D D WW+ Sbjct: 2 STYVQALFDFDPQED-----GELGFRRGDFIHVMDNSDPNWWKG 40 >2EDP-A nrPDB Length = 100 Score = 59.5 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 45/91 (49%), Gaps = 7/91 (7%) Query: 61 MEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFV 120 +Y + L+ G + GF++ GG ++ + ++KI GG AA ++R D ++ + Sbjct: 10 FQYVPVQLQ-GGAPWGFTLKGGLEHCE-----PLTVSKIEDGGKAALSQKMRTGDELVNI 63 Query: 121 NEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 N + A+ +K + I++L V RR Sbjct: 64 NGTPLYGSR-QEALILIKGSFRILKLIVRRR 93 Score = 56.8 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 26/80 (32%), Positives = 46/80 (57%), Gaps = 2/80 (2%) Query: 315 VIHRGSTGLGFNIVGG-EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHE 373 V +G GF + GG E E + +S I GG A LS ++R GD+++++NG L S + Sbjct: 15 VQLQGGAPWGFTLKGGLEHCEPLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQ 73 Query: 374 QAAIALKNAGQTVTIIAQYK 393 +A I +K + + + +I + + Sbjct: 74 EALILIKGSFRILKLIVRRR 93 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 43/79 (54%), Gaps = 6/79 (7%) Query: 171 GFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVA 230 GF++ GG+ + + V+KI +GG A +++ GD+++ +N L ++A+ Sbjct: 24 GFTLKGGLEHCE-----PLTVSKIEDGGKAALSQKMRTGDELVNINGTPLYG-SRQEALI 77 Query: 231 ALKNTYDVVYLKVAKPSNA 249 +K ++ ++ L V + ++ Sbjct: 78 LIKGSFRILKLIVRRRNSG 96 >2V90-A nrPDB Length = 96 Score = 59.5 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 39/84 (46%), Gaps = 4/84 (4%) Query: 66 ITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDV 125 + LE+G G GF + + + P F+ ++ PG A + G ++ D ++ V V Sbjct: 7 LHLEKGPQGFGFLLR---EEKGLDGRPGQFLWEVDPGLPAKKAG-MQAGDRLVAVAGESV 62 Query: 126 REVTHSAAVEALKEAGSIVRLYVM 149 + H V ++ GS V L V+ Sbjct: 63 EGLGHEETVSRIQGQGSCVSLTVV 86 Score = 59.1 bits (141), Expect = 7e-09, Method: Composition-based stats. Identities = 27/88 (30%), Positives = 44/88 (50%), Gaps = 4/88 (4%) Query: 161 IKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL 220 + L KGP+G GF + G PG ++ ++ G A K G +Q GD+++AV + Sbjct: 7 LHLEKGPQGFGFLLREEKGLDGRPGQ---FLWEVDPGLPAKKAG-MQAGDRLVAVAGESV 62 Query: 221 EDVMHEDAVAALKNTYDVVYLKVAKPSN 248 E + HE+ V+ ++ V L V P Sbjct: 63 EGLGHEETVSRIQGQGSCVSLTVVDPEA 90 Score = 55.6 bits (132), Expect = 8e-08, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 42/84 (50%), Gaps = 4/84 (4%) Query: 310 EPRRIVIHRGSTGLGFNIV---GGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVD 366 +PR + + +G G GF + G + G F+ + G PA +G ++ GD++++V G Sbjct: 3 KPRCLHLEKGPQGFGFLLREEKGLDGRPGQFLWEVDPGLPAKKAG-MQAGDRLVAVAGES 61 Query: 367 LRNASHEQAAIALKNAGQTVTIIA 390 + HE+ ++ G V++ Sbjct: 62 VEGLGHEETVSRIQGQGSCVSLTV 85 >1M5Z-A nrPDB Length = 91 Score = 59.5 bits (142), Expect = 5e-09, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 42/89 (47%), Gaps = 3/89 (3%) Query: 308 PREPRRIVIHR--GSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGV 365 P E ++ +++ G GF++ G +G+++ I GP DL G L+ D++L VN V Sbjct: 4 PVELHKVTLYKDSGMEDFGFSVADGLLEKGVYVKNIRPAGPGDL-GGLKPYDRLLQVNHV 62 Query: 366 DLRNASHEQAAIALKNAGQTVTIIAQYKP 394 R+ + +G + ++ P Sbjct: 63 RTRDFDCCLVVPLIAESGNKLDLVISRNP 91 Score = 56.4 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 43/96 (44%), Gaps = 9/96 (9%) Query: 57 TEGEMEYEEITLERGN--SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 + +E ++TL + + GFS+A G + +++ I P G G L+ Sbjct: 1 SPTPVELHKVTLYKDSGMEDFGFSVADG------LLEKGVYVKNIRPAGPGDL-GGLKPY 53 Query: 115 DSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 D +L VN V R+ V + E+G+ + L + R Sbjct: 54 DRLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISR 89 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 9/95 (9%) Query: 153 PPAEKVMEIKLIKGP--KGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGD 210 P ++ ++ L K + GFS+A G+ + +YV I G G L+ D Sbjct: 2 PTPVELHKVTLYKDSGMEDFGFSVADGL------LEKGVYVKNIRPAGPGDLGG-LKPYD 54 Query: 211 KILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 ++L VN V D V + + + + L +++ Sbjct: 55 RLLQVNHVRTRDFDCCLVVPLIAESGNKLDLVISR 89 >2PKT-A nrPDB Length = 91 Score = 56.8 bits (135), Expect = 3e-08, Method: Composition-based stats. Identities = 23/74 (31%), Positives = 36/74 (48%), Gaps = 2/74 (2%) Query: 324 GFNIVGGEDGE-GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 382 GF +VGG+D E + IS + G A L L GD I +++G + N +H +A +K Sbjct: 16 GFRLVGGKDFEQPLAISRVTPGSKAAL-ANLCIGDVITAIDGENTSNMTHLEAQNRIKGC 74 Query: 383 GQTVTIIAQYKPEE 396 +T+ E Sbjct: 75 TDNLTLTVARSEHE 88 Score = 54.9 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 165 KGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVM 224 +GP GF + GG + + ++++ G A L IGD I A++ ++ Sbjct: 10 QGPGPWGFRLVGGKD-----FEQPLAISRVTPGSKAALA-NLCIGDVITAIDGENTSNMT 63 Query: 225 HEDAVAALKNTYDVVYLKVAKPSN 248 H +A +K D + L VA+ + Sbjct: 64 HLEAQNRIKGCTDNLTLTVARSEH 87 Score = 51.8 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 20/76 (26%), Positives = 33/76 (43%), Gaps = 6/76 (7%) Query: 76 GFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVE 135 GF + GG D + + I+++ PG AA L + D I ++ + +TH A Sbjct: 16 GFRLVGGKDF-----EQPLAISRVTPGSKAALA-NLCIGDVITAIDGENTSNMTHLEAQN 69 Query: 136 ALKEAGSIVRLYVMRR 151 +K + L V R Sbjct: 70 RIKGCTDNLTLTVARS 85 >1UJV-A nrPDB Length = 96 Score = 56.0 bits (133), Expect = 5e-08, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 46/104 (44%), Gaps = 13/104 (12%) Query: 55 NGTEGEMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVN 114 +G+ G+ E +T+ +G G GF+IA + I G L Sbjct: 3 SGSSGQAELMTLTIVKGAQGFGFTIADSPTGQRVKQILDI------QGCP-----GLCEG 51 Query: 115 DSILFVNEVDVREVTHSAAVEALKEA--GSIVRLYVMRRKPPAE 156 D I+ +N+ +V+ ++H+ V+ LK+ GS L + R P+ Sbjct: 52 DLIVEINQQNVQNLSHTEVVDILKDCPIGSETSLIIHRGSGPSS 95 Score = 51.8 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 310 EPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 E + I +G+ G GF I G+ + + G P L +GD I+ +N +++N Sbjct: 10 ELMTLTIVKGAQGFGFTIADSPTGQRVKQILDIQGCPG-----LCEGDLIVEINQQNVQN 64 Query: 370 ASHEQAAIALKNA--GQTVTIIAQYKPEEYS 398 SH + LK+ G ++I S Sbjct: 65 LSHTEVVDILKDCPIGSETSLIIHRGSGPSS 95 Score = 46.0 bits (107), Expect = 6e-05, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 41/94 (43%), Gaps = 13/94 (13%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 ++M + ++KG +G GF+IA Q + I +G L GD I+ +N Sbjct: 10 ELMTLTIVKGAQGFGFTIADSPTGQRVKQILDI------QGCP-----GLCEGDLIVEIN 58 Query: 217 SVGLEDVMHEDAVAALKNT--YDVVYLKVAKPSN 248 ++++ H + V LK+ L + + S Sbjct: 59 QQNVQNLSHTEVVDILKDCPIGSETSLIIHRGSG 92 >3PV2-A nrPDB Length = 451 Score = 55.6 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 35/170 (20%), Positives = 65/170 (38%), Gaps = 15/170 (8%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH-SAAVEALKEAGSIVRLYVMRR 151 ++++ P A G L+ D I +N+ + + T + L+ GS V++ V R Sbjct: 283 GALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVKTTISLLR-VGSTVKIIVERD 340 Query: 152 KPPAEKVMEIKLIKGPKG---------LGFSIAGGVGNQHIPGDN-SIYVTKIIEGGAAH 201 P + IK + G ++ G+ + V E A Sbjct: 341 NKPLTLSAVVTDIKSHEQKLQSNNPFLYGLALRAFEQESPPHGNVIGVQVVGASENSAGW 400 Query: 202 KDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYL 251 + G ++ GD I++ N + DV +A K +V + + P + YL Sbjct: 401 RAG-IRPGDIIISANKKPVTDVKSLQTIAQEKKKELLVQV-LRGPGSMYL 448 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 51/237 (21%), Positives = 94/237 (39%), Gaps = 14/237 (5%) Query: 203 DGRLQIGDKILAV-NSVGLEDVMHED-----AVAALKNTYDVVY-LKVAKPSNAYLSDSY 255 +L++GD ++A+ N GL + V+ALK + + ++ ++A ++ Sbjct: 145 SDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGN 204 Query: 256 APPD-ITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRI 314 + + N S Y G P + + VA+ ++ I R I Sbjct: 205 SGGALVNAKGELIGINTAILSPYGGNVGIGFAIPINMVK--DVAQQIIKFGSIHRGLMGI 262 Query: 315 VIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + + L + ED +G +S + PA+L+G L+ GD I +N + A+ + Sbjct: 263 FVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVK 321 Query: 375 AAIALKNAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGF 431 I+L G TV II + + + A + D++ L S L R F Sbjct: 322 TTISLLRVGSTVKIIVERDNKPLT-LSAVVTDIKSH--EQKLQSNNPFLYGLALRAF 375 Score = 43.7 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 32/203 (15%), Positives = 58/203 (28%), Gaps = 44/203 (21%) Query: 188 SIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPS 247 V+++ A G L+ GD I +N + +L V + V + Sbjct: 283 GALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVKTTISLLRVGSTVKIIVERD- 340 Query: 248 NAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDI 307 + + S + + SH L ++ +P Y + E Sbjct: 341 -----------NKPLTLSAVVTDIKSHEQKLQSN--------NPFLYGLALRAFEQE--- 378 Query: 308 PREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 367 P VI G+ + +G +R GD I+S N + Sbjct: 379 -SPPHGNVI------------------GVQVVGASENSAGWRAG-IRPGDIIISANKKPV 418 Query: 368 RNASHEQAAIALKNAGQTVTIIA 390 + Q K V ++ Sbjct: 419 TDVKSLQTIAQEKKKELLVQVLR 441 >1ZUB-A nrPDB Length = 114 Score = 55.6 bits (132), Expect = 7e-08, Method: Composition-based stats. Identities = 25/101 (24%), Positives = 43/101 (42%), Gaps = 4/101 (3%) Query: 289 TSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE----GIFISFILAG 344 + P + P + + R + LG +VGG+ + G FI+ + G Sbjct: 5 SHPVTWQPSKEGDRLIGRVILNKRTTMPKESGALLGLKVVGGKMTDLGRLGAFITKVKKG 64 Query: 345 GPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQT 385 AD+ G LR GD++L NG L A++E+ + + Sbjct: 65 SLADVVGHLRAGDEVLEWNGKPLPGATNEEVYNIILESKSE 105 Score = 52.2 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 33/84 (39%), Gaps = 2/84 (2%) Query: 69 ERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREV 128 + + LG + GG FITK+ G A G LR D +L N + Sbjct: 33 KESGALLGLKVVGGKMTD--LGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGA 90 Query: 129 THSAAVEALKEAGSIVRLYVMRRK 152 T+ + E+ S ++ ++ + Sbjct: 91 TNEEVYNIILESKSEPQVEIIVSR 114 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 34/78 (43%), Gaps = 4/78 (5%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG + GG G ++TK+ +G A G L+ GD++L N L +E+ Sbjct: 39 LGLKVVGG--KMTDLGRLGAFITKVKKGSLADVVGHLRAGDEVLEWNGKPLPGATNEEVY 96 Query: 230 AAL--KNTYDVVYLKVAK 245 + + V + V++ Sbjct: 97 NIILESKSEPQVEIIVSR 114 >3BPU-A nrPDB Length = 88 Score = 54.9 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 40/86 (46%), Gaps = 5/86 (5%) Query: 310 EPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 E + I +G G GF I G G + I+ P S L++GD I+ VN +++ Sbjct: 3 ELITVHIVKGPMGFGFTIADSPGGGGQRVKQIV-DSP--RSRGLKEGDLIVEVNKKNVQA 59 Query: 370 ASHEQAAIALKNA--GQTVTIIAQYK 393 +H Q L + G VT++ Q + Sbjct: 60 LTHNQVVDMLVESPKGSEVTLLVQRQ 85 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 45/94 (47%), Gaps = 11/94 (11%) Query: 60 EMEYEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILF 119 ME + + +G G GF+IA + +I+ ++ L+ D I+ Sbjct: 1 SMELITVHIVKGPMGFGFTIA------DSPGGGGQRVKQIV-DSPRSR--GLKEGDLIVE 51 Query: 120 VNEVDVREVTHSAAVEALKEA--GSIVRLYVMRR 151 VN+ +V+ +TH+ V+ L E+ GS V L V R+ Sbjct: 52 VNKKNVQALTHNQVVDMLVESPKGSEVTLLVQRQ 85 Score = 48.7 bits (114), Expect = 8e-06, Method: Composition-based stats. Identities = 24/93 (25%), Positives = 42/93 (45%), Gaps = 11/93 (11%) Query: 157 KVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVN 216 +++ + ++KGP G GF+IA PG V +I+ + L+ GD I+ VN Sbjct: 3 ELITVHIVKGPMGFGFTIA------DSPGGGGQRVKQIV-DSPRSRG--LKEGDLIVEVN 53 Query: 217 SVGLEDVMHEDAVAALKNT--YDVVYLKVAKPS 247 ++ + H V L + V L V + + Sbjct: 54 KKNVQALTHNQVVDMLVESPKGSEVTLLVQRQT 86 >1V62-A nrPDB Length = 117 Score = 54.5 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 37/84 (44%), Gaps = 5/84 (5%) Query: 161 IKLIKGPKG-LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVG 219 ++++K P LG S+ + + I + +I + G L GD IL+++ Sbjct: 19 VEIVKTPGSALGISLT----TTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTS 74 Query: 220 LEDVMHEDAVAALKNTYDVVYLKV 243 +E +A L + + V L++ Sbjct: 75 MEHCSLLEATKLLASISEKVRLEI 98 Score = 53.3 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 36/96 (37%), Gaps = 7/96 (7%) Query: 72 NSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHS 131 S LG S+ + + I I +I P + G L D IL ++ + + Sbjct: 26 GSALGISLT----TTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTSMEHCSLL 81 Query: 132 AAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGP 167 A + L VRL ++ P + ++ GP Sbjct: 82 EATKLLASISEKVRLEIL---PVPQSQRPLRPSSGP 114 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 19/82 (23%), Positives = 33/82 (40%), Gaps = 2/82 (2%) Query: 309 REPRRIVIHRGSTGLGFNIV--GGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVD 366 ++ + LG ++ + I I I D SG L GD ILS++G Sbjct: 15 GPLMVEIVKTPGSALGISLTTTSLRNKSVITIDRIKPASVVDRSGALHPGDHILSIDGTS 74 Query: 367 LRNASHEQAAIALKNAGQTVTI 388 + + S +A L + + V + Sbjct: 75 MEHCSLLEATKLLASISEKVRL 96 >1WFG-A nrPDB Length = 131 Score = 53.3 bits (126), Expect = 3e-07, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%) Query: 323 LGFNIVGGEDGEG----IFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIA 378 LG +VGG+ E FI+ + G AD G LR GD++L NG L+ A+ E+ Sbjct: 50 LGLKVVGGKMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVYNI 109 Query: 379 LKNAGQT--VTIIAQYKPE 395 + + V ++ Sbjct: 110 ILESKPEPQVELVVSRSGP 128 Score = 48.7 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 69 ERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREV 128 + LG + GG FITK+ G A G LR D +L N ++ Sbjct: 44 RDSGAMLGLKVVGG--KMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGA 101 Query: 129 THSAAVEALKEAGSI--VRLYVMRRKP 153 T + E+ V L V R P Sbjct: 102 TFEEVYNIILESKPEPQVELVVSRSGP 128 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 33/80 (41%), Gaps = 4/80 (5%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAV 229 LG + GG G ++TK+ +G A G L+ GD++L N L+ E+ Sbjct: 50 LGLKVVGG--KMTESGRLCAFITKVKKGSLADTVGHLRPGDEVLEWNGRLLQGATFEEVY 107 Query: 230 AAL--KNTYDVVYLKVAKPS 247 + V L V++ Sbjct: 108 NIILESKPEPQVELVVSRSG 127 >1V6B-A nrPDB Length = 118 Score = 53.3 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 4/77 (5%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 + + IK L ++ GGV + + V+ + EGGAA + G + GD+I+A+N Sbjct: 19 VRLLRIKKEGSLDLALEGGVDSPVGK----VVVSAVYEGGAAERHGGVVKGDEIMAINGK 74 Query: 219 GLEDVMHEDAVAALKNT 235 + D +A AAL+ Sbjct: 75 IVTDYTLAEAEAALQKA 91 Score = 53.3 bits (126), Expect = 4e-07, Method: Composition-based stats. Identities = 23/87 (26%), Positives = 43/87 (49%), Gaps = 2/87 (2%) Query: 298 AKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE--GIFISFILAGGPADLSGELRK 355 A + E I + R++ + L + GG D + +S + GG A+ G + K Sbjct: 5 AATMFSPEQIAGKDVRLLRIKKEGSLDLALEGGVDSPVGKVVVSAVYEGGAAERHGGVVK 64 Query: 356 GDQILSVNGVDLRNASHEQAAIALKNA 382 GD+I+++NG + + + +A AL+ A Sbjct: 65 GDEIMAINGKIVTDYTLAEAEAALQKA 91 Score = 52.2 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 39/90 (43%), Gaps = 7/90 (7%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 + L ++ GG D+P + ++ + GGAA + G + D I+ +N V + T Sbjct: 25 KKEGSLDLALEGGVDSPV----GKVVVSAVYEGGAAERHGGVVKGDEIMAINGKIVTDYT 80 Query: 130 HSAAVEALK---EAGSIVRLYVMRRKPPAE 156 + A AL+ G V+ PP E Sbjct: 81 LAEAEAALQKAWNQGGDWIDLVVAVCPPKE 110 >4A8B-A nrPDB Length = 436 Score = 52.5 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 32/166 (19%), Positives = 70/166 (42%), Gaps = 16/166 (9%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK 152 F+++++PG +A+ G ++ D I +N + + A E G+ V+L ++R Sbjct: 264 GAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNG 322 Query: 153 PPAEKVMEIKLIKG---------PKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKD 203 P E + + P G +++ G G I + ++++G A + Sbjct: 323 KPLEVEVTLDTSTSSSASAEMITPALEGATLSDGQLKD---GGKGIKIDEVVKGSPAAQA 379 Query: 204 GRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNA 249 G LQ D I+ VN + + + L ++ L++ + + + Sbjct: 380 G-LQKDDVIIGVNRDRVNSI--AEMRKVLAAKPAIIALQIVRGNES 422 Score = 32.5 bits (72), Expect = 0.72, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 333 GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQY 392 G F+S +L G + +G ++ GD I S+NG L + + ++ IA G V + Sbjct: 262 QRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR 320 Query: 393 KPEE 396 + Sbjct: 321 NGKP 324 >3CYY-A nrPDB Length = 92 Score = 52.5 bits (124), Expect = 6e-07, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 33/66 (50%) Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSN 248 I+V +I + A +DG +Q GD +L +N E++ DA ++ + + + V + Sbjct: 25 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQRDER 84 Query: 249 AYLSDS 254 A L + Sbjct: 85 ATLLNV 90 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 35/86 (40%), Gaps = 7/86 (8%) Query: 310 EPRRIVIHRGST--GLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 367 +P ++ + + + G + IF+ I A G +++GD +L +NG Sbjct: 2 KPTKVTLVKSAKNEEYGLRLAS-----HIFVKEISQDSLAARDGNIQEGDVVLKINGTVT 56 Query: 368 RNASHEQAAIALKNAGQTVTIIAQYK 393 N S A ++ + + ++ Q Sbjct: 57 ENMSLTDAKTLIERSKGKLKMVVQRD 82 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 29/57 (50%) Query: 94 IFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 IF+ +I AA+DG ++ D +L +N ++ + A ++ + +++ V R Sbjct: 25 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQR 81 >4YNN-A nrPDB Length = 448 Score = 51.8 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 30/160 (18%), Positives = 61/160 (38%), Gaps = 12/160 (7%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH-SAAVEALKEAGSIVRLYVMRR 151 ++++ A G L+ D I+ +N+ + + T + L+ AGS ++ ++R Sbjct: 280 GALVSQVNQNSPAQLAG-LKSGDVIVQINDTKITQATQVKTTISLLR-AGSTAKIKILRD 337 Query: 152 KPPAEKVMEIKLIKGPKG---------LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHK 202 P +E+ IK + G ++ G+ +A Sbjct: 338 NKPLTLDVEVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASETSAGW 397 Query: 203 DGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLK 242 L+ GD I++ N ++D+ AVA K +V + Sbjct: 398 RAGLRPGDIIISANKTPVKDIKSLQAVAHEKGKQLLVQVL 437 Score = 51.4 bits (121), Expect = 1e-06, Method: Composition-based stats. Identities = 49/222 (22%), Positives = 89/222 (40%), Gaps = 12/222 (5%) Query: 203 DGRLQIGDKILAV-NSVGLEDVMHED-----AVAALKNTYDVVY-LKVAKPSNAYLSDSY 255 +L++GD ++A+ N GL + V+ALK + + ++ ++A ++ Sbjct: 142 SDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGN 201 Query: 256 APPD-ITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRI 314 A + N S Y G P + + VA+ ++ I R I Sbjct: 202 AGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAK--DVAQQIIKFGSIHRGLMGI 259 Query: 315 VIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + + L ++ ED +G +S + PA L+G L+ GD I+ +N + A+ + Sbjct: 260 FVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAG-LKSGDVIVQINDTKITQATQVK 318 Query: 375 AAIALKNAGQTVTI-IAQYKPEEYSRFEAKIHDLREQLMNSS 415 I+L AG T I I + E EQ + S+ Sbjct: 319 TTISLLRAGSTAKIKILRDNKPLTLDVEVTDIKKHEQKLQSN 360 Score = 35.6 bits (80), Expect = 0.077, Method: Composition-based stats. Identities = 31/203 (15%), Positives = 58/203 (28%), Gaps = 44/203 (21%) Query: 188 SIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPS 247 V+++ + A G L+ GD I+ +N + +L +K+ + + Sbjct: 280 GALVSQVNQNSPAQLAG-LKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILRDN 338 Query: 248 NAYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDI 307 D T +H S++ +L SP + V ++G + Sbjct: 339 KPLTLDV-----EVTDIKKHEQKLQSNNPFLYGLALRNFEQESPPHGNVVGVQVVGASET 393 Query: 308 PREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDL 367 A LR GD I+S N + Sbjct: 394 --------------------------------------SAGWRAGLRPGDIIISANKTPV 415 Query: 368 RNASHEQAAIALKNAGQTVTIIA 390 ++ QA K V ++ Sbjct: 416 KDIKSLQAVAHEKGKQLLVQVLR 438 >2RCZ-A nrPDB Length = 81 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 30/57 (52%) Query: 189 IYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 I+V +I + A +DG +Q GD +L +N E++ DA ++ + + + V + Sbjct: 23 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQR 79 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 32/85 (37%), Gaps = 5/85 (5%) Query: 309 REPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 +V R + G + IF+ I A G +++GD +L +NG Sbjct: 1 GSKVTLVKSRKNEEYGLRLAS-----HIFVKEISQDSLAARDGNIQEGDVVLKINGTVTE 55 Query: 369 NASHEQAAIALKNAGQTVTIIAQYK 393 N S A ++ + + ++ Q Sbjct: 56 NMSLTDAKTLIERSKGKLKMVVQRD 80 Score = 49.5 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 29/57 (50%) Query: 94 IFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMR 150 IF+ +I AA+DG ++ D +L +N ++ + A ++ + +++ V R Sbjct: 23 IFVKEISQDSLAARDGNIQEGDVVLKINGTVTENMSLTDAKTLIERSKGKLKMVVQR 79 >5MV8-B nrPDB Length = 130 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 22/77 (28%), Positives = 38/77 (49%), Gaps = 4/77 (5%) Query: 159 MEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV 218 + + IK L ++ GGV + + V+ + E GAA + G + GD+I+A+N Sbjct: 31 VRLLRIKKEGSLDLALEGGVDSPIGK----VVVSAVYERGAAERHGGIVKGDEIMAINGK 86 Query: 219 GLEDVMHEDAVAALKNT 235 + D +A AAL+ Sbjct: 87 IVTDYTLAEADAALQKA 103 Score = 50.2 bits (118), Expect = 3e-06, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 41/84 (48%), Gaps = 2/84 (2%) Query: 301 LLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGE--GIFISFILAGGPADLSGELRKGDQ 358 + E I + R++ + L + GG D + +S + G A+ G + KGD+ Sbjct: 20 MFTPEQIMGKDVRLLRIKKEGSLDLALEGGVDSPIGKVVVSAVYERGAAERHGGIVKGDE 79 Query: 359 ILSVNGVDLRNASHEQAAIALKNA 382 I+++NG + + + +A AL+ A Sbjct: 80 IMAINGKIVTDYTLAEADAALQKA 103 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 22/90 (24%), Positives = 38/90 (42%), Gaps = 7/90 (7%) Query: 70 RGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVT 129 + L ++ GG D+P + ++ + GAA + G + D I+ +N V + T Sbjct: 37 KKEGSLDLALEGGVDSPI----GKVVVSAVYERGAAERHGGIVKGDEIMAINGKIVTDYT 92 Query: 130 HSAAVEALK---EAGSIVRLYVMRRKPPAE 156 + A AL+ G V+ PP E Sbjct: 93 LAEADAALQKAWNQGGDWIDLVVAVCPPKE 122 >3PV4-A nrPDB Length = 354 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 44/202 (21%), Positives = 83/202 (41%), Gaps = 11/202 (5%) Query: 203 DGRLQIGDKILAV-NSVGLEDVMHED-----AVAALKNTYDVVY-LKVAKPSNAYLSDSY 255 +L++GD ++A+ N GL + V+ALK + + ++ ++A ++ Sbjct: 145 SDKLEVGDFVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGN 204 Query: 256 APPD-ITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRI 314 + + N S Y G P + + VA+ ++ I R I Sbjct: 205 SGGALVNAKGELIGINTAILSPYGGNVGIGFAIPINMVK--DVAQQIIKFGSIHRGLMGI 262 Query: 315 VIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + + L + ED +G +S + PA+L+G L+ GD I +N + A+ + Sbjct: 263 FVQHLTPELAQAMGYPEDFQGALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVK 321 Query: 375 AAIALKNAGQTVTIIAQYKPEE 396 I+L G TV II + + Sbjct: 322 TTISLLRVGSTVKIIVERDNKP 343 Score = 39.1 bits (89), Expect = 0.006, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 28/65 (43%), Gaps = 3/65 (4%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH-SAAVEALKEAGSIVRLYVMRR 151 ++++ P A G L+ D I +N+ + + T + L+ GS V++ V R Sbjct: 283 GALVSQVNPNSPAELAG-LKAGDIITQINDTKITQATQVKTTISLLR-VGSTVKIIVERD 340 Query: 152 KPPAE 156 P Sbjct: 341 NKPLT 345 >4C2G-A nrPDB Length = 446 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 37/220 (16%), Positives = 68/220 (30%), Gaps = 33/220 (15%) Query: 177 GVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTY 236 G+G + D I + + A K G L+ D+I+++N + AV ++ Sbjct: 71 GIGAEVGMEDGKIIIVSPFKKSPAEKAG-LKPNDEIISINGESMAGKDLNHAVLKIRGKK 129 Query: 237 D-VVYLKVAKPSN----AYLSDSYAPPDITTSYSQHLDNEISHSSYLGTDYPTAMTPTSP 291 V +K+ +P ++ P T S G T Sbjct: 130 GSSVSMKIQRPGTKKQLSFRIKRAEIPLETV--------FASEKKVQGHSVGYIAISTFS 181 Query: 292 RRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSG 351 + ED + R + + GL ++ G G + IL Sbjct: 182 EHTA---------EDFAKALRELEK-KEIEGLVIDVRGNPGGYLQSVEEILK----HFVT 227 Query: 352 ELRKGDQILSVNGVD---LRNASHEQA--AIALKNAGQTV 386 + + QI NG +H++A + + G Sbjct: 228 KDQPYIQIAERNGDKKRYFSTLTHKKAYPVNVITDKGSAA 267 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 25/153 (16%), Positives = 59/153 (38%), Gaps = 8/153 (5%) Query: 321 TGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALK 380 G+G + G + I I PA+ +G L+ D+I+S+NG + A + ++ Sbjct: 70 EGIGAEV--GMEDGKIIIVSPFKKSPAEKAG-LKPNDEIISINGESMAGKDLNHAVLKIR 126 Query: 381 N-AGQTVTIIAQYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDY 439 G +V++ Q ++ + R ++ ++ + ++ + I F Sbjct: 127 GKKGSSVSMKIQR---PGTKKQLSFRIKRAEIPLETVFASEKKVQGHSVGYIAIST-FSE 182 Query: 440 DKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQ 472 +D + L + + L + G+ + Sbjct: 183 HTAEDFAKALRELEKKEIEGLVIDVRGNPGGYL 215 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 21/88 (23%), Positives = 34/88 (38%), Gaps = 5/88 (5%) Query: 82 GTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALK-EA 140 G +D I I A + G L+ ND I+ +N + + AV ++ + Sbjct: 71 GIGAEVGMEDGKIIIVSPFKKSPAEKAG-LKPNDEIISINGESMAGKDLNHAVLKIRGKK 129 Query: 141 GSIVRLYVMRRKPPAEKVMEIKLIKGPK 168 GS V + + R P K IK + Sbjct: 130 GSSVSMKIQR---PGTKKQLSFRIKRAE 154 >1R6J-A nrPDB Length = 82 Score = 49.8 bits (117), Expect = 5e-06, Method: Composition-based stats. Identities = 25/82 (30%), Positives = 39/82 (47%), Gaps = 8/82 (9%) Query: 310 EPRRIVIHRGSTG-LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLR 368 +PR I +H+ STG +GF G+ I+ I+ A +G L + + I +NG ++ Sbjct: 4 DPRTITMHKDSTGHVGFIFKNGK------ITSIVKDSSAARNGLLTEHN-ICEINGQNVI 56 Query: 369 NASHEQAAIALKNAGQTVTIIA 390 Q A L +G VTI Sbjct: 57 GLKDSQIADILSTSGTVVTITI 78 >4YO1-A nrPDB Length = 351 Score = 49.5 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 46/208 (22%), Positives = 84/208 (40%), Gaps = 12/208 (5%) Query: 203 DGRLQIGDKILAV-NSVGLEDVMHED-----AVAALKNTYDVVY-LKVAKPSNAYLSDSY 255 +L++GD ++A+ N GL + V+ALK + + ++ ++A ++ Sbjct: 142 SDKLEVGDYVVAIGNPFGLNSFGNSQSATFGIVSALKRSDLNIEGVENFIQTDAAINPGN 201 Query: 256 APPD-ITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRI 314 A + N S Y G P + + VA+ ++ I R I Sbjct: 202 AGGALVNAKGELIGINTAIISPYGGNVGIGFAIPINMAK--DVAQQIIKFGSIHRGLMGI 259 Query: 315 VIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + + L ++ ED +G +S + PA L+G L+ GD I+ +N + A+ + Sbjct: 260 FVQHLTPELAQSMGYAEDFQGALVSQVNQNSPAQLAG-LKSGDVIVQINDTKITQATQVK 318 Query: 375 AAIALKNAGQTVTI-IAQYKPEEYSRFE 401 I+L AG T I I + E Sbjct: 319 TTISLLRAGSTAKIKILRDNKPLTLDVE 346 Score = 39.1 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 34/74 (45%), Gaps = 3/74 (4%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH-SAAVEALKEAGSIVRLYVMRR 151 ++++ A G L+ D I+ +N+ + + T + L+ AGS ++ ++R Sbjct: 280 GALVSQVNQNSPAQLAG-LKSGDVIVQINDTKITQATQVKTTISLLR-AGSTAKIKILRD 337 Query: 152 KPPAEKVMEIKLIK 165 P +E+ IK Sbjct: 338 NKPLTLDVEVTDIK 351 Score = 33.7 bits (75), Expect = 0.28, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 188 SIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 V+++ + A G L+ GD I+ +N + +L +K+ + Sbjct: 280 GALVSQVNQNSPAQLAG-LKSGDVIVQINDTKITQATQVKTTISLLRAGSTAKIKILR 336 >3SOE-A nrPDB Length = 113 Score = 48.7 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 32/111 (28%), Positives = 47/111 (42%), Gaps = 17/111 (15%) Query: 63 YEEITLERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNE 122 I L +G G GF+IA D+P I ++ G L+ D I + Sbjct: 13 LVTIPLIKGPKGFGFAIA---DSPTGQKVKMILDSQWCQG--------LQKGDIIKEIYH 61 Query: 123 VDVREVTHSAAVEALKE--AGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLG 171 +V+ +TH VE LK+ G+ V L ++R PP+ K K G G Sbjct: 62 QNVQNLTHLQVVEVLKQFPVGADVPLLILRGGPPS----PTKTAKMGSGSG 108 Score = 44.5 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 39/101 (38%), Gaps = 7/101 (6%) Query: 313 RIVIHRGSTGLGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH 372 I + +G G GF I G+ + IL + L+KGD I + +++N +H Sbjct: 15 TIPLIKGPKGFGFAIADSPTGQK--VKMILD---SQWCQGLQKGDIIKEIYHQNVQNLTH 69 Query: 373 EQAAIALKNA--GQTVTIIAQYKPEEYSRFEAKIHDLREQL 411 Q LK G V ++ AK+ Q+ Sbjct: 70 LQVVEVLKQFPVGADVPLLILRGGPPSPTKTAKMGSGSGQI 110 Score = 44.1 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 25/92 (27%), Positives = 39/92 (42%), Gaps = 13/92 (14%) Query: 158 VMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS 217 ++ I LIKGPKG GF+IA + I ++ +G LQ GD I + Sbjct: 13 LVTIPLIKGPKGFGFAIA---DSPTGQKVKMILDSQWCQG--------LQKGDIIKEIYH 61 Query: 218 VGLEDVMHEDAVAALKNT--YDVVYLKVAKPS 247 ++++ H V LK V L + + Sbjct: 62 QNVQNLTHLQVVEVLKQFPVGADVPLLILRGG 93 >5Y2D-A nrPDB Length = 465 Score = 48.7 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 36/181 (19%), Positives = 56/181 (30%), Gaps = 24/181 (13%) Query: 68 LERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 +ERG G+G G + + + A + G L V D I VN V+ Sbjct: 261 IERGYLGVGLQDLSGDLQNSYDNKEGAVVISVEKDSPAKKAGIL-VWDLITEVNGKKVKN 319 Query: 128 VTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGP-KGLGFSIAGGVG------- 179 + V L V+R K + + K P K S G Sbjct: 320 TNELRNLIGSMLPNQRVTLKVIRDKKERAFTLTLAERKNPNKKETISAQNGAQGQLNGLQ 379 Query: 180 ---------NQHIPGDN--SIYVTKIIEGGAAHKDGRLQIGD---KILAVNSVGLEDVMH 225 D+ + V+++ E A + G + G+ KI V + D H Sbjct: 380 VEDLTQETKRSMRLSDDVQGVLVSQVNENSPAEQAG-FRQGNIITKIEEVEVKSVADFNH 438 Query: 226 E 226 Sbjct: 439 A 439 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 37/241 (15%), Positives = 80/241 (33%), Gaps = 39/241 (16%) Query: 152 KPPAEKVMEI-KLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGD 210 K ++++ K+ +G G+G G V + + A K G L + D Sbjct: 249 KDTVTQLIKTGKIERGYLGVGLQDLSGDLQNSYDNKEGAVVISVEKDSPAKKAGIL-VWD 307 Query: 211 KILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYAPPDITTSYSQHLDN 270 I VN +++ + V LKV + Sbjct: 308 LITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIR------------------------- 342 Query: 271 EISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEED-IPREPRRIVIHRGSTGLGFNIVG 329 A T T R +P K+ + ++ + + + + ++ Sbjct: 343 ---------DKKERAFTLTLAERKNPNKKETISAQNGAQGQLNGLQVEDLTQETKRSMRL 393 Query: 330 GEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNA-SHEQAAIALKNAGQTVTI 388 +D +G+ +S + PA+ +G R+G+ I + V++++ A K + + Sbjct: 394 SDDVQGVLVSQVNENSPAEQAG-FRQGNIITKIEEVEVKSVADFNHALEKYKGKPKRFLV 452 Query: 389 I 389 + Sbjct: 453 L 453 Score = 37.9 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 8/87 (9%) Query: 316 IHRGSTGLGFNIVGGE------DGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 I RG G+G + G+ + EG + + PA +G L D I VNG ++N Sbjct: 261 IERGYLGVGLQDLSGDLQNSYDNKEGAVVISVEKDSPAKKAGIL-VWDLITEVNGKKVKN 319 Query: 370 ASHEQAAIALKNAGQTVTI-IAQYKPE 395 + + I Q VT+ + + K E Sbjct: 320 TNELRNLIGSMLPNQRVTLKVIRDKKE 346 >1FC9-A nrPDB Length = 388 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 36/187 (19%), Positives = 70/187 (37%), Gaps = 20/187 (10%) Query: 267 HLDNEISHSSYLGTDYPTAMTPTSPRR---YSPVAKDLLGEED----IPREPRRIVIHRG 319 ++D + S+ RR Y + K L +D R + RG Sbjct: 20 YVDKSFNGQSWFKLRETYLKKEPMDRRAQTYDAIRKLLAVLDDPFTRFLEPSRLAALRRG 79 Query: 320 S----TGLGFNIV-GGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQ 374 + TG+G I G G+ + + GGPA+ +G R GD I++V+G ++ S Sbjct: 80 TAGSVTGVGLEITYDGGSGKDVVVLTPAPGGPAEKAGA-RAGDVIVTVDGTAVKGLSLYD 138 Query: 375 AAIALK---NAGQTVTIIAQYKPEEYSRFEAKIHDLREQLMN----SSLGSGTASLRSNP 427 + L+ ++ V + A P + + + S++ + + Sbjct: 139 VSDLLQGEADSQVEVVLHAPGAPSNTRTLQLTRQKVTINPVTFTTCSNVAAAALPPGAAK 198 Query: 428 KRGFYIR 434 ++ Y+R Sbjct: 199 QQLGYVR 205 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 45/307 (14%), Positives = 99/307 (32%), Gaps = 20/307 (6%) Query: 143 IVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAG-GVGNQHIPGDN-SIYVTKIIEGGAA 200 I +L + P + +L +G S+ G G+ + G + V GG A Sbjct: 53 IRKLLAVLDDPFTRFLEPSRLAALRRGTAGSVTGVGLEITYDGGSGKDVVVLTPAPGGPA 112 Query: 201 HKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYD-VVYLKVAKPSNAYLSDSYAPPD 259 K G + GD I+ V+ ++ + D L+ D V + + P + + Sbjct: 113 EKAGA-RAGDVIVTVDGTAVKGLSLYDVSDLLQGEADSQVEVVLHAPGAPSNTRT----- 166 Query: 260 ITTSYSQHLDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRG 319 + + + N ++ ++ + ++ V + Sbjct: 167 LQLTRQKVTINPVTFTTCSNVAAAALPPGAAKQQLGYVRLATFNSNTTAAAQQAFTELSK 226 Query: 320 STGLGFNIVGGEDGEGIFISFI-LAGGPADLSGELRKGD-----QILSVNGVDLRNASHE 373 G + +G G+F + + +A D + D I S +G + +A+ Sbjct: 227 QGVAGLVLDIRNNGGGLFPAGVNVARMLVDRGDLVLIADSQGIRDIYSADGNSIDSAT-P 285 Query: 374 QAAIALKNAGQTVTIIA----QYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKR 429 + + ++A K + L + +++ S GSG A + + Sbjct: 286 LVVLVNRGTASASEVLAGALKDSKRGLIAGERTFGKGLIQTVVDLSDGSGVAVTVARYQT 345 Query: 430 GFYIRAL 436 + Sbjct: 346 PAGVDIN 352 Score = 43.7 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 21/95 (22%), Positives = 39/95 (41%), Gaps = 8/95 (8%) Query: 73 SGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSA 132 +G+G I G + + PGG A + G R D I+ V+ V+ ++ Sbjct: 85 TGVGLEIT-----YDGGSGKDVVVLTPAPGGPAEKAGA-RAGDVIVTVDGTAVKGLSLYD 138 Query: 133 AVEALK-EAGSIVRLYV-MRRKPPAEKVMEIKLIK 165 + L+ EA S V + + P + +++ K Sbjct: 139 VSDLLQGEADSQVEVVLHAPGAPSNTRTLQLTRQK 173 >2EYZ-A nrPDB Length = 304 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 45/205 (21%), Positives = 72/205 (35%), Gaps = 21/205 (10%) Query: 395 EEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSF 454 E Y L E + S GSG + + Y+RALFD++ + + L F Sbjct: 102 EFYKIHYLDTTTLIEPVSRSRQGSGVILRQ---EEAEYVRALFDFNGNDE-----EDLPF 153 Query: 455 RFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSK-RRVERREWSRLKAKDWGSSSGS 513 + GD+L + D +E+WW A + G IP R + + A G+ GS Sbjct: 154 KKGDILRIRDKPEEQWWNA-----EDSEGKRGMIPVPYVEKYRPASASVSALIGGNQEGS 208 Query: 514 QGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDLLSEFPDKFGSCVPHTTRPKREY 573 + Q V+ P + GP R P+ + T Sbjct: 209 HPQPLGGPEPGPYAQPSVNTPLPNLQNGPIYARVIQK---RVPNAYDK----TALALEVG 261 Query: 574 EIDGRDYHFVSSREKMEKDIQAHKF 598 E+ VS + + E + + F Sbjct: 262 ELVKVTKINVSGQWEGECNGKRGHF 286 >2LQW-A nrPDB Length = 303 Score = 45.6 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 37/171 (21%), Positives = 65/171 (38%), Gaps = 31/171 (18%) Query: 432 YIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSK 491 Y+R L+D+ ++ L F+ G++L +I+ +E+WW AR ++ +G IP Sbjct: 127 YVRTLYDFPGND-----AEDLPFKKGEILVIIEKPEEQWWSAR-----NKDGRVGMIPVP 176 Query: 492 RRVERREWSRLKAKDWGSSSGSQGREDSVLSY---ETVTQMEVHYARPIIILGPTKDRAN 548 VE+ S K +S S G + +Y +T T + P + P N Sbjct: 177 Y-VEKLVRSSPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPLPSTQN 235 Query: 549 DDLLSE----------FPDKFGSCVPHTTRPKR-------EYEIDGRDYHF 582 + ++ V + R E E++GR F Sbjct: 236 GPVFAKAIQKRVPCAYDKTALALEVGDIVKVTRMNINGQWEGEVNGRKGLF 286 >2EAQ-A nrPDB Length = 90 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 19/72 (26%), Positives = 36/72 (50%), Gaps = 3/72 (4%) Query: 323 LGFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNA 382 GF I D GIF++ + AG PA+ S +L+ D+I+++N ++ A+ A Sbjct: 19 FGFTI--KWDIPGIFVASVEAGSPAEFS-QLQVDDEIIAINNTKFSYNDSKEWEEAMAKA 75 Query: 383 GQTVTIIAQYKP 394 +T ++ + Sbjct: 76 QETGHLVMDVRR 87 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 31/78 (39%), Gaps = 9/78 (11%) Query: 75 LGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAV 134 GF+I D P IF+ + G A +L+V+D I+ +N Sbjct: 19 FGFTIK--------WDIPGIFVASVEAGSPAEFS-QLQVDDEIIAINNTKFSYNDSKEWE 69 Query: 135 EALKEAGSIVRLYVMRRK 152 EA+ +A L + R+ Sbjct: 70 EAMAKAQETGHLVMDVRR 87 Score = 37.9 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 33/73 (45%), Gaps = 12/73 (16%) Query: 170 LGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGL---EDVMHE 226 GF+I + I+V + G A +LQ+ D+I+A+N+ + E Sbjct: 19 FGFTIKWDIP--------GIFVASVEAGSPAEFS-QLQVDDEIIAINNTKFSYNDSKEWE 69 Query: 227 DAVAALKNTYDVV 239 +A+A + T +V Sbjct: 70 EAMAKAQETGHLV 82 >2KL1-A nrPDB Length = 94 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 39/91 (42%), Gaps = 7/91 (7%) Query: 88 IGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEAL--KEAGSIVR 145 + + +++ ++P AA GRL D I ++ + T V + K+AG VR Sbjct: 1 MNEAKGVYVMSVLPNMPAA--GRLEAGDRIAAIDGQPIN--TSEQIVSYVREKQAGDRVR 56 Query: 146 LYVMR-RKPPAEKVMEIKLIKGPKGLGFSIA 175 + +R RK +++ P +G + Sbjct: 57 VTFIRDRKQHEAELVLKPFPHHPNQIGLGVT 87 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 30/61 (49%), Gaps = 6/61 (9%) Query: 331 EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIAL--KNAGQTVTI 388 + +G+++ +L PA G L GD+I +++G + + EQ + K AG V + Sbjct: 2 NEAKGVYVMSVLPNMPAA--GRLEAGDRIAAIDGQPIN--TSEQIVSYVREKQAGDRVRV 57 Query: 389 I 389 Sbjct: 58 T 58 Score = 39.1 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 14/63 (22%), Positives = 27/63 (42%), Gaps = 6/63 (9%) Query: 187 NSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALK--NTYDVVYLKVA 244 +YV ++ A GRL+ GD+I A++ + E V+ ++ D V + Sbjct: 5 KGVYVMSVLPNMPAA--GRLEAGDRIAAIDGQPIN--TSEQIVSYVREKQAGDRVRVTFI 60 Query: 245 KPS 247 + Sbjct: 61 RDR 63 >5JD8-A nrPDB Length = 334 Score = 42.5 bits (98), Expect = 6e-04, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 52/139 (37%), Gaps = 10/139 (7%) Query: 287 TPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTG-----LGFNIVGGEDGEGIFISFI 341 TP P A E + R+ R I + G TG N G + GI + + Sbjct: 199 TPEGIGFAIPTALATKVMEKLIRDGRVIRGYIGITGEEYPPFNANDNGSDRVHGIKVKKV 258 Query: 342 LAGGPADLSGELRKGDQILSVNGVDLRNA--SHEQAAIALKNAGQTVTIIAQYKPEEYSR 399 GPA +G + GD IL+VN + + +Q A G T+ ++ ++ + Sbjct: 259 SPDGPAAQAG-IHVGDIILNVNNKPATSVIETMDQVAEV--RPGTTIPVLLLRNGQQIAV 315 Query: 400 FEAKIHDLREQLMNSSLGS 418 + +++ + Sbjct: 316 QITITELDQNEMLTTQAAD 334 Score = 39.1 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 23/79 (29%), Positives = 27/79 (34%), Gaps = 9/79 (11%) Query: 77 FSIAGGTDNPHIGDDPS------IFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREV-- 128 I G P +D I + K+ P G AAQ G + V D IL VN V Sbjct: 230 IGITGEEYPPFNANDNGSDRVHGIKVKKVSPDGPAAQAG-IHVGDIILNVNNKPATSVIE 288 Query: 129 THSAAVEALKEAGSIVRLY 147 T E V L Sbjct: 289 TMDQVAEVRPGTTIPVLLL 307 Score = 37.1 bits (84), Expect = 0.030, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 23/62 (37%), Gaps = 5/62 (8%) Query: 188 SIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDV--MHEDAVAALKNTYDVVYLKVAK 245 I V K+ G A + G + +GD IL VN+ V + + + + + Sbjct: 252 GIKVKKVSPDGPAAQAG-IHVGDIILNVNNKPATSVIETMDQVAEV--RPGTTIPVLLLR 308 Query: 246 PS 247 Sbjct: 309 NG 310 >5T69-A nrPDB Length = 367 Score = 42.1 bits (97), Expect = 8e-04, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 26/39 (66%), Gaps = 1/39 (2%) Query: 331 EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 + +GI + +L G PA+ +G +R+GD I++V+G + + Sbjct: 288 PEVDGILVMRVLPGTPAERAG-IRRGDVIVAVDGTPISD 325 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 21/40 (52%), Gaps = 1/40 (2%) Query: 88 IGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 I + I + +++PG A + G +R D I+ V+ + + Sbjct: 287 IPEVDGILVMRVLPGTPAERAG-IRRGDVIVAVDGTPISD 325 Score = 37.9 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 183 IPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLED 222 IP + I V +++ G A + G ++ GD I+AV+ + D Sbjct: 287 IPEVDGILVMRVLPGTPAERAG-IRRGDVIVAVDGTPISD 325 >5WQL-C nrPDB Length = 682 Score = 42.1 bits (97), Expect = 9e-04, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 36/91 (39%), Gaps = 7/91 (7%) Query: 82 GTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNE-----VDVREVTHSAAVEA 136 G DD I ++ GG AA+ + V D I+ V + VDV V Sbjct: 247 GIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVAL 306 Query: 137 LKEA-GSIVRLYVM-RRKPPAEKVMEIKLIK 165 +K GS VRL ++ K + + + + Sbjct: 307 IKGPKGSKVRLEILPAGKGTKTRTVTLTRER 337 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 48/123 (39%), Gaps = 15/123 (12%) Query: 324 GFNIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNG-----VDLRNASHEQAAIA 378 G V D + I+ ++AGGPA S + GD+I+ V VD+ + Sbjct: 247 GIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVAL 306 Query: 379 LKN-AGQTVTIIA-------QYKPEEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRG 430 +K G V + + + +R ++ D ++ ++G + P G Sbjct: 307 IKGPKGSKVRLEILPAGKGTKTRTVTLTRERIRLEDRAVKMSVKTVGKEKVGVLDIP--G 364 Query: 431 FYI 433 FY+ Sbjct: 365 FYV 367 Score = 39.1 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 32/79 (40%), Gaps = 6/79 (7%) Query: 177 GVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS-----VGLEDVMHEDAVAA 231 G+G D+ + ++ GG A K + +GDKI+ V V + +D VA Sbjct: 247 GIGAVLQMDDDYTVINSMVAGGPAAKSKAISVGDKIVGVGQTGKPMVDVIGWRLDDVVAL 306 Query: 232 LKNTYD-VVYLKVAKPSNA 249 +K V L++ Sbjct: 307 IKGPKGSKVRLEILPAGKG 325 >3EHQ-A nrPDB Length = 222 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 25/65 (38%), Gaps = 11/65 (16%) Query: 434 RALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRR 493 RAL+ ++ L GD++++ D D WW+ G IPS Sbjct: 18 RALYTFEPRTP-----DELYIEEGDIIYITDMSDTNWWKGTSKGR------TGLIPSNYV 66 Query: 494 VERRE 498 E+ E Sbjct: 67 AEQAE 71 >2R98-A nrPDB Length = 456 Score = 41.0 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 34/157 (21%), Positives = 50/157 (31%), Gaps = 19/157 (12%) Query: 492 RRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGPTKDRANDDL 551 R + L A++ S + E L V +E R I+ G +L Sbjct: 232 SRPDGTLAETLSAQEAQSLAEHAASETRRLISSAVAALEGGVHRVQILNGAADGSLLQEL 291 Query: 552 LSE-------FPDKF-------GSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHK 597 + + F +PH R E G H SRE +E I Sbjct: 292 FTRNGIGTSIAKEAFVSIRQAHSGDIPHIAALIRPLEEQGILLH--RSREYLENHISEFS 349 Query: 598 FIEAGQYNSHLYGTSVQSVREVAEQGKHCILDVSANA 634 +E +LYG + A+ G+ L VS A Sbjct: 350 ILEHD---GNLYGCAALKTFAEADCGEIACLAVSPQA 383 >3GCO-A nrPDB Length = 340 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 20/95 (21%), Positives = 37/95 (38%), Gaps = 21/95 (22%) Query: 81 GGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEA 140 GG D I + ++ P G AA G ++VND I+ V+ A+ AL+ Sbjct: 259 GGIDQLQ-----GIVVNEVSPDGPAANAG-IQVNDLIISVDNKP--------AISALETM 304 Query: 141 GSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIA 175 + + V+ + +++ K L + Sbjct: 305 AQVAEI-------RPGSVIPVVVMRDDKQLTLQVT 332 Score = 37.5 bits (85), Expect = 0.020, Method: Composition-based stats. Identities = 17/66 (25%), Positives = 31/66 (46%), Gaps = 2/66 (3%) Query: 329 GGEDG-EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVT 387 GG D +GI ++ + GPA +G ++ D I+SV+ +A A +A G + Sbjct: 259 GGIDQLQGIVVNEVSPDGPAANAG-IQVNDLIISVDNKPAISALETMAQVAEIRPGSVIP 317 Query: 388 IIAQYK 393 ++ Sbjct: 318 VVVMRD 323 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 30/67 (44%), Gaps = 14/67 (20%) Query: 176 GGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNT 235 GG+ I V ++ G A G +Q+ D I++V++ + A++AL+ Sbjct: 259 GGIDQLQ-----GIVVNEVSPDGPAANAG-IQVNDLIISVDN--------KPAISALETM 304 Query: 236 YDVVYLK 242 V ++ Sbjct: 305 AQVAEIR 311 >3MH6-A nrPDB Length = 456 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 25/130 (19%), Positives = 52/130 (40%), Gaps = 9/130 (6%) Query: 333 GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQY 392 G F+S +L A +G ++ GD I S+NG + + + +A + G +T+ Sbjct: 285 QRGAFVSQVLPNSSAAKAG-IKAGDVITSLNGKPISSFAALRAQVGTMPVGSKLTLGLLR 343 Query: 393 KPEEYSRFEAKIHDLREQLMNSSL--GSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQ 450 ++ + + Q+ +SS+ G A + + K + G + Sbjct: 344 DGKQVNVNLELQQSSQNQVDSSSIFNGIEGAEMSNKGKDQGVVVNNVK------TGTPAA 397 Query: 451 ALSFRFGDVL 460 + + GDV+ Sbjct: 398 QIGLKKGDVI 407 >2D8I-A nrPDB Length = 114 Score = 39.8 bits (91), Expect = 0.004, Method: Composition-based stats. Identities = 26/118 (22%), Positives = 53/118 (44%), Gaps = 22/118 (18%) Query: 55 NGTEGEME-----YEEITLERGNS---GLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAA 106 +G+ GE+E + I +E+ ++ GFS++ ++ +++ + G A+ Sbjct: 3 SGSSGEIEICPKVTQSIHIEKSDTAADTYGFSLSSVEEDGIRR----LYVNSVKETGLAS 58 Query: 107 QDGRLRVNDSILFVNEVDVREVTHSAAV--EALKEAGSIVRL-YVMRRKPPAEKVMEI 161 + G L+ D IL +N + A+ LK+ S L ++R P E+ +E Sbjct: 59 KKG-LKAGDEILEINN------RAADALNSSMLKDFLSQPSLGLLVRTYPELEEGVES 109 Score = 37.9 bits (86), Expect = 0.016, Method: Composition-based stats. Identities = 22/104 (21%), Positives = 44/104 (42%), Gaps = 10/104 (9%) Query: 305 EDIPREPRRIVIHRG---STGLGFNIVGGEDGEGI---FISFILAGGPADLSGELRKGDQ 358 E P+ + I I + + GF++ E+ +GI +++ + G A G L+ GD+ Sbjct: 10 EICPKVTQSIHIEKSDTAADTYGFSLSSVEE-DGIRRLYVNSVKETGLASKKG-LKAGDE 67 Query: 359 ILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEA 402 IL +N + L ++ ++ + PE E+ Sbjct: 68 ILEINNRAADALNSSMLKDFLSQP--SLGLLVRTYPELEEGVES 109 Score = 36.4 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 19/67 (28%), Positives = 30/67 (44%), Gaps = 6/67 (8%) Query: 152 KPPAEKVMEIKL-IKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGD 210 P + + I+ GFS++ G +YV + E G A K G L+ GD Sbjct: 12 CPKVTQSIHIEKSDTAADTYGFSLSS----VEEDGIRRLYVNSVKETGLASKKG-LKAGD 66 Query: 211 KILAVNS 217 +IL +N+ Sbjct: 67 EILEINN 73 >5Y28-A nrPDB Length = 357 Score = 39.4 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 34/95 (35%), Gaps = 2/95 (2%) Query: 152 KPPAEKVMEI-KLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGD 210 K ++++ K+ +G G+G G V + + A K G L + D Sbjct: 249 KDTVTQLIKTGKIERGYLGVGLQDLSGDLQNSYDNKEGAVVISVEKDSPAKKAGIL-VWD 307 Query: 211 KILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAK 245 I VN +++ + V LKV + Sbjct: 308 LITEVNGKKVKNTNELRNLIGSMLPNQRVTLKVIR 342 Score = 38.3 bits (87), Expect = 0.012, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 29/88 (32%), Gaps = 1/88 (1%) Query: 68 LERGNSGLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVRE 127 +ERG G+G G + + + A + G L V D I VN V+ Sbjct: 261 IERGYLGVGLQDLSGDLQNSYDNKEGAVVISVEKDSPAKKAGIL-VWDLITEVNGKKVKN 319 Query: 128 VTHSAAVEALKEAGSIVRLYVMRRKPPA 155 + V L V+R K Sbjct: 320 TNELRNLIGSMLPNQRVTLKVIRDKKER 347 Score = 38.3 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 24/87 (27%), Positives = 38/87 (43%), Gaps = 8/87 (9%) Query: 316 IHRGSTGLGFNIVGGE------DGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRN 369 I RG G+G + G+ + EG + + PA +G L D I VNG ++N Sbjct: 261 IERGYLGVGLQDLSGDLQNSYDNKEGAVVISVEKDSPAKKAGIL-VWDLITEVNGKKVKN 319 Query: 370 ASHEQAAIALKNAGQTVTI-IAQYKPE 395 + + I Q VT+ + + K E Sbjct: 320 TNELRNLIGSMLPNQRVTLKVIRDKKE 346 >2KJP-A nrPDB Length = 91 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 19/64 (29%), Positives = 35/64 (54%), Gaps = 2/64 (3%) Query: 335 GIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKP 394 GI+ S ++ PA G++ GD+I+S +G + ++A I+ K AG VT+ + + Sbjct: 2 GIYASSVVENMPAK--GKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTLKIEREE 59 Query: 395 EEYS 398 +E Sbjct: 60 KEKR 63 Score = 38.7 bits (88), Expect = 0.008, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 37/90 (41%), Gaps = 15/90 (16%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEAL-----KEAGSIVRLY 147 I+ + ++ A G++ V D I+ + + + +A + + K+AG V L Sbjct: 2 GIYASSVVENMPAK--GKIEVGDKIISADGKN-----YQSAEKLIDYISSKKAGDKVTLK 54 Query: 148 VMRRKPPAEKVMEIKL---IKGPKGLGFSI 174 + R + + +K G+G S+ Sbjct: 55 IEREEKEKRVTLTLKQFPDEPDRAGIGVSL 84 Score = 36.4 bits (82), Expect = 0.048, Method: Composition-based stats. Identities = 17/77 (22%), Positives = 31/77 (40%), Gaps = 4/77 (5%) Query: 187 NSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKP 246 N IY + ++E A G++++GDKI++ + + + K D V LK+ + Sbjct: 1 NGIYASSVVENMPAK--GKIEVGDKIISADGKNYQSAEKLIDYISSKKAGDKVTLKIERE 58 Query: 247 SNAYLS--DSYAPPDIT 261 PD Sbjct: 59 EKEKRVTLTLKQFPDEP 75 >6F3F-A nrPDB Length = 455 Score = 38.7 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 43/298 (14%), Positives = 96/298 (32%), Gaps = 37/298 (12%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS---- 490 AL+DY+ + LSF+ G+ L +++ + +WW A T G+IPS Sbjct: 10 ALYDYESRTE-----TDLSFKKGERLQIVNNTEGDWWLAH----SLSTGQTGYIPSNYVA 60 Query: 491 KRRVERREWSRLKAKDWGSSSGSQGREDS----VLSYETVTQMEVHYARPIIILGPTKDR 546 + E S ++ L E+ T Y + K Sbjct: 61 PSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGA-YCLSVSDFDNAKGL 119 Query: 547 ANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKD--IQAHKFIEAGQY 604 D G + T+ ++ Y+ + + + + Sbjct: 120 NVKHYKIRKLDSGGFYITSRTQFNSLQQL--VAYYSKHADGLCHRLTTVCPTSKPQTQGL 177 Query: 605 NSHLYGTSVQSVREVAEQGKHCILDV---SANAVRRLQAAHLHPIAIFIRPRSLENVLEI 661 + +S+R + G+ C +V + N R+ L P + P + ++ Sbjct: 178 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGT--MSPEAFLQEAQV 235 Query: 662 NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVP 719 K++ E+ + + ++ + + + + ++ +G Y+ +P Sbjct: 236 MKKLRHEKLVQLYAVVSEEPI--------YIVTEYMNK--GSLLDFLKGETGKYLRLP 283 >4RI0-A nrPDB Length = 332 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 9/53 (16%), Positives = 23/53 (43%), Gaps = 2/53 (3%) Query: 83 TDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTH-SAAV 134 ++ I++ ++ P + + G ++ D I+ VN + + + AV Sbjct: 246 SNPDFPEVSSGIYVQEVAPNSPSQR-GGIQDGDIIVKVNGRPLVDSSELQEAV 297 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 331 EDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASH-EQAA 376 E GI++ + P+ G ++ GD I+ VNG L ++S ++A Sbjct: 252 EVSSGIYVQEVAPNSPSQR-GGIQDGDIIVKVNGRPLVDSSELQEAV 297 Score = 35.6 bits (80), Expect = 0.069, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 23/50 (46%), Gaps = 2/50 (4%) Query: 181 QHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMH-EDAV 229 + IYV ++ + + G +Q GD I+ VN L D ++AV Sbjct: 249 DFPEVSSGIYVQEVAPNSPSQRGG-IQDGDIIVKVNGRPLVDSSELQEAV 297 >3JV3-A nrPDB Length = 283 Score = 38.7 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 13/54 (24%), Positives = 23/54 (42%), Gaps = 11/54 (20%) Query: 437 FDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 +DY D L+F G +++V++ D +WW+ +G PS Sbjct: 9 YDYTAQND-----DELAFSKGQIINVLNKEDPDWWKGEVSGQ------VGLFPS 51 >2H8H-A nrPDB Length = 535 Score = 37.5 bits (85), Expect = 0.019, Method: Composition-based stats. Identities = 43/298 (14%), Positives = 96/298 (32%), Gaps = 37/298 (12%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS---- 490 AL+DY+ + LSF+ G+ L +++ + +WW A T G+IPS Sbjct: 90 ALYDYESRTE-----TDLSFKKGERLQIVNNTEGDWWLAH----SLSTGQTGYIPSNYVA 140 Query: 491 KRRVERREWSRLKAKDWGSSSGSQGREDS----VLSYETVTQMEVHYARPIIILGPTKDR 546 + E S ++ L E+ T Y + K Sbjct: 141 PSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGA-YCLSVSDFDNAKGL 199 Query: 547 ANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKD--IQAHKFIEAGQY 604 D G + T+ ++ Y+ + + + + Sbjct: 200 NVKHYKIRKLDSGGFYITSRTQFNSLQQL--VAYYSKHADGLCHRLTTVCPTSKPQTQGL 257 Query: 605 NSHLYGTSVQSVREVAEQGKHCILDV---SANAVRRLQAAHLHPIAIFIRPRSLENVLEI 661 + +S+R + G+ C +V + N R+ L P + P + ++ Sbjct: 258 AKDAWEIPRESLRLEVKLGQGCFGEVWMGTWNGTTRVAIKTLKPGT--MSPEAFLQEAQV 315 Query: 662 NKRITEEQARKAFDRATKLEQEFTECFSAIVEGDSFEEIYHKVKRVIEDLSGPYIWVP 719 K++ E+ + + ++ + + + + ++ +G Y+ +P Sbjct: 316 MKKLRHEKLVQLYAVVSEEPI--------YIVTEYMSK--GSLLDFLKGETGKYLRLP 363 >3NUM-A nrPDB Length = 332 Score = 37.5 bits (85), Expect = 0.019, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 29/62 (46%), Gaps = 4/62 (6%) Query: 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYK 393 G +I ++ PA+ +G L++ D I+S+NG + + + T+ ++ + Sbjct: 254 SGAYIIEVIPDTPAE-AGGLKENDVIISINGQSVVS---ANDVSDVIKRESTLNMVVRRG 309 Query: 394 PE 395 E Sbjct: 310 NE 311 Score = 34.1 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 16/59 (27%), Positives = 28/59 (47%), Gaps = 4/59 (6%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 +I ++IP A G L+ ND I+ +N V V+ + + +K S + + V R Sbjct: 255 GAYIIEVIPDTPAE-AGGLKENDVIISINGQSV--VSANDVSDVIKR-ESTLNMVVRRG 309 >2PZ1-A nrPDB Length = 466 Score = 37.1 bits (84), Expect = 0.026, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 3/77 (3%) Query: 450 QALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWGS 509 Q L F+ GDV+ V+DA + EWW RV F+ + RV + E + A G+ Sbjct: 45 QELGFKAGDVIEVMDATNREWWWG-RVADGEGWFPASFV--RLRVNQDEPADDDAPLAGN 101 Query: 510 SSGSQGREDSVLSYETV 526 S G ++ S + + Sbjct: 102 SGAEDGGAEAQSSKDQM 118 >4NXP-A nrPDB Length = 94 Score = 37.1 bits (84), Expect = 0.029, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 26/49 (53%), Gaps = 5/49 (10%) Query: 319 GSTGLGFNIVGGEDGEGI---FISFILAGGPADLSGELRKGDQILSVNG 364 + GF++ E+ +GI +++ + G A G L+ GD+IL +N Sbjct: 18 AADTYGFSLSSVEE-DGIRRLYVNSVKETGLASKKG-LKAGDEILEINN 64 Score = 36.4 bits (82), Expect = 0.041, Method: Composition-based stats. Identities = 13/62 (20%), Positives = 29/62 (46%), Gaps = 8/62 (12%) Query: 63 YEEITLERGNS---GLGFSIAGGTDNPHIGDDPSIFITKIIPGGAAAQDGRLRVNDSILF 119 I +E+ ++ GFS++ ++ +++ + G A++ G L+ D IL Sbjct: 7 THSIHIEKSDTAADTYGFSLSSVEEDGIRR----LYVNSVKETGLASKKG-LKAGDEILE 61 Query: 120 VN 121 +N Sbjct: 62 IN 63 Score = 36.4 bits (82), Expect = 0.042, Method: Composition-based stats. Identities = 17/51 (33%), Positives = 25/51 (49%), Gaps = 5/51 (9%) Query: 167 PKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNS 217 GFS++ G +YV + E G A K G L+ GD+IL +N+ Sbjct: 19 ADTYGFSLSS----VEEDGIRRLYVNSVKETGLASKKG-LKAGDEILEINN 64 >4XI2-A nrPDB Length = 446 Score = 36.4 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 39/92 (42%), Gaps = 12/92 (13%) Query: 433 IRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKR 492 + AL+DY + L R G+ +++ + WW+AR + G+IPS Sbjct: 6 VVALYDY-----MPMNANDLQLRKGEEYFILEESNLPWWRAR-----DKNGQEGYIPSNY 55 Query: 493 RVERREWSRLKAKDWGSSSGSQGREDSVLSYE 524 E + + +W S ++ + + +L E Sbjct: 56 ITEAEDSIEM--YEWYSKHMTRSQAEQLLKQE 85 >3GF9-A nrPDB Length = 295 Score = 36.4 bits (82), Expect = 0.045, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 24/45 (53%), Gaps = 5/45 (11%) Query: 429 RGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 +G + A++DY + LSF G +++V++ D +WWQ Sbjct: 17 QGCQVIAMYDYAANNE-----DELSFSKGQLINVMNKDDPDWWQG 56 >2KJK-A nrPDB Length = 100 Score = 36.0 bits (81), Expect = 0.053, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 34/87 (39%), Gaps = 8/87 (9%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEAL--KEAGSIVRLYVM 149 +++ + AA G L D I ++ + ++ + K+ G V++ Sbjct: 7 DGVYVLSVKEDVPAA--GILHAGDLITEIDGQSFKSS--QEFIDYIHSKKVGDTVKIKYK 62 Query: 150 RRKPPAEKVMEIKLI--KGPKGLGFSI 174 E +++ I KG G+G ++ Sbjct: 63 HGNKNEEASIKLTAIDKKGTPGIGITL 89 Score = 35.6 bits (80), Expect = 0.081, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 21/61 (34%), Gaps = 4/61 (6%) Query: 187 NSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAA-LKNTYDVVYLKVAK 245 + +YV + E A G L GD I ++ + E K D V +K Sbjct: 7 DGVYVLSVKEDVPAA--GILHAGDLITEIDGQSFKS-SQEFIDYIHSKKVGDTVKIKYKH 63 Query: 246 P 246 Sbjct: 64 G 64 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYK 393 +G+++ + PA G L GD I ++G S ++ + + T+ +YK Sbjct: 7 DGVYVLSVKEDVPAA--GILHAGDLITEIDGQSF--KSSQEFIDYIHSKKVGDTVKIKYK 62 >3AGK-A nrPDB Length = 373 Score = 36.0 bits (81), Expect = 0.063, Method: Composition-based stats. Identities = 39/251 (15%), Positives = 74/251 (29%), Gaps = 23/251 (9%) Query: 425 SNPKRGFYIRAL--FDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSET 482 P R FY R F D +D + A+ ++ D + R+ E Sbjct: 114 PEPIRVFYYRTDKRFITDFLEDMVEDNNAIGI----IIVERDQATIGLLKGARLEVLKE- 168 Query: 483 DDIGFIPSKRRVERREWSRLKAKDWGSSSGSQGREDSVLSYETVTQMEVHYARPIIILGP 542 GF+P K ++ + R + + S V E + +I+ GP Sbjct: 169 -LEGFVPGKHKMGGQSQRRYERIIEQMVDEFFKKVGEEASNLLVPLAEKGVLKGVIVAGP 227 Query: 543 TKDRANDDLLSEFPDKFGSCVPHTTRPKREYEIDGRDYHFVSSREKMEKDIQAHKFIEAG 602 E + R K+ + D + + E ++A K +EA Sbjct: 228 G---LAKQEFVE-GNYLDY------RLKKILAPELVDVAYQGLQGLKEAVMKAEKVVEAQ 277 Query: 603 QYNSHLYGTSVQSVREVAEQGKHCILDVSANAVRRLQAAHLHPIAIFIRPRSLENVLEIN 662 Y + + G + A + + + S E++ E Sbjct: 278 MYRDAVNAMEEFKLHLAKGTGMIVYGEKDVEAALEMG-----AVKTLLIHESREDLEEWV 332 Query: 663 KRITEEQARKA 673 ++ A+ Sbjct: 333 EKAKSSGAQVI 343 >5M3O-A nrPDB Length = 334 Score = 35.2 bits (79), Expect = 0.098, Method: Composition-based stats. Identities = 20/74 (27%), Positives = 33/74 (44%), Gaps = 6/74 (8%) Query: 188 SIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAALKNTYDVVYLKVAKPS 247 + + K+I G AH+ G L+ GD ILA+ +++ ED A++ L V Sbjct: 258 GVLIHKVILGSPAHRAG-LRPGDVILAIGEQMVQNA--EDVYEAVRTQSQ---LAVQIRR 311 Query: 248 NAYLSDSYAPPDIT 261 Y P++T Sbjct: 312 GRETLTLYVTPEVT 325 >3I1E-A nrPDB Length = 90 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 21/61 (34%), Gaps = 4/61 (6%) Query: 187 NSIYVTKIIEGGAAHKDGRLQIGDKILAVNSVGLEDVMHEDAVAA-LKNTYDVVYLKVAK 245 + +YV + E A G L GD I ++ + E K D V +K Sbjct: 2 DGVYVLSVKEDVPAA--GILHAGDLITEIDGQSFKS-SQEFIDYIHSKKVGDTVKIKYKH 58 Query: 246 P 246 Sbjct: 59 G 59 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 334 EGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYK 393 +G+++ + PA G L GD I ++G S ++ + + T+ +YK Sbjct: 2 DGVYVLSVKEDVPAA--GILHAGDLITEIDGQSF--KSSQEFIDYIHSKKVGDTVKIKYK 57 Score = 34.1 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 15/85 (17%), Positives = 32/85 (37%), Gaps = 8/85 (9%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEAL--KEAGSIVRLYVM 149 +++ + AA G L D I ++ + ++ + K+ G V++ Sbjct: 2 DGVYVLSVKEDVPAA--GILHAGDLITEIDGQSFKSS--QEFIDYIHSKKVGDTVKIKYK 57 Query: 150 RRKPPAEKVMEIKLI--KGPKGLGF 172 E +++ I KG G+G Sbjct: 58 HGNKNEEASIKLTAIDKKGTPGIGI 82 >4O06-A nrPDB Length = 106 Score = 34.8 bits (78), Expect = 0.12, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 37/87 (42%), Gaps = 4/87 (4%) Query: 92 PSIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVE--ALKEAGSIVRLYVM 149 P FI++++PG + + ++V+D ++ + V + ++ +K + + ++ Sbjct: 19 PFAFISEVVPGSPSDKAD-IKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLL 77 Query: 150 RR-KPPAEKVMEIKLIKGPKGLGFSIA 175 R + + + G LG I Sbjct: 78 REGQILKTSLTPSRNWNGRGLLGCRIQ 104 Score = 29.8 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 31/64 (48%), Gaps = 3/64 (4%) Query: 337 FISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAI--ALKNAGQTVTIIAQYKP 394 FIS ++ G P+D +++ D+++S+ V N S Q +KN + + ++ + Sbjct: 22 FISEVVPGSPSDK-ADIKVDDKLISIGNVHAANHSKLQNIQMVVMKNEDRPLPVLLLREG 80 Query: 395 EEYS 398 + Sbjct: 81 QILK 84 >5O2P-A nrPDB Length = 100 Score = 34.4 bits (77), Expect = 0.15, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 27/83 (32%), Gaps = 9/83 (10%) Query: 443 KDCGFLSQALSFRFGDVLHVID---AGDEEWWQARRVHSDSETDDIGFIPSKRRVERREW 499 + LSFR GD++ V++ G + WW G +P R Sbjct: 15 DNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQ------GIVPGNRLKILVGM 68 Query: 500 SRLKAKDWGSSSGSQGREDSVLS 522 K G S ++DS Sbjct: 69 YDKKPAGSGGSGSGSEKQDSPPP 91 >1GBQ-A nrPDB Length = 74 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 12/56 (21%) Query: 435 ALFDYDKTKDCGFLSQALSFRFGDVLHVIDAG-DEEWWQARRVHSDSETDDIGFIP 489 A +D+ T D LSF+ GD+L V++ D+ W++A D GFIP Sbjct: 14 AKYDFKATAD-----DELSFKRGDILKVLNEECDQNWYKAELNGKD------GFIP 58 >4MT6-A nrPDB Length = 456 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 19/29 (65%) Query: 451 ALSFRFGDVLHVIDAGDEEWWQARRVHSD 479 L+F+ GDV+ V+DA +++WW + + Sbjct: 33 ELAFKAGDVIKVLDASNKDWWWGQIDDEE 61 >1YWO-A nrPDB Length = 64 Score = 34.1 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 11/48 (22%), Positives = 22/48 (45%), Gaps = 5/48 (10%) Query: 426 NPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 +P ++ALFDY ++ L+F ++ ++ D WW+ Sbjct: 2 SPTFKSAVKALFDYKAQRE-----DELTFTKSAIIQNVEKQDGGWWRG 44 >3QO6-A nrPDB Length = 348 Score = 34.1 bits (76), Expect = 0.23, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 44/149 (29%), Gaps = 37/149 (24%) Query: 122 EVDVREVTHSAAVEALKEAGSIVRLYVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQ 181 + T V+ L G + R + + P + V + LG S Sbjct: 209 GFSIPVDTVGGIVDQLVRFGKVTRPILGIKFAPDQSV---------EQLGVS-------- 251 Query: 182 HIPGDNSIYVTKIIEGGAAHKDG----------RLQIGDKILAVNSVGLEDVMHEDAVAA 231 + V G A K G RL +GD I +VN + + D Sbjct: 252 ------GVLVLDAPPSGPAGKAGLQSTKRDGYGRLVLGDIITSVNGTKVSNGS--DLYRI 303 Query: 232 LKNT--YDVVYLKVAKPSNAYLSDSYAPP 258 L D V ++V + + P Sbjct: 304 LDQCKVGDEVTVEVLRGDHKEKISVTLEP 332 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 31/88 (35%), Gaps = 23/88 (26%) Query: 334 EGIFISFILAGGPADLSG----------ELRKGDQILSVNGVDLRN------------AS 371 G+ + GPA +G L GD I SVNG + N Sbjct: 251 SGVLVLDAPPSGPAGKAGLQSTKRDGYGRLVLGDIITSVNGTKVSNGSDLYRILDQCKVG 310 Query: 372 HEQAAIALKNAGQT-VTIIAQYKPEEYS 398 E L+ + +++ + KP+E + Sbjct: 311 DEVTVEVLRGDHKEKISVTLEPKPDESA 338 >3STJ-A nrPDB Length = 345 Score = 34.1 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 32/64 (50%), Gaps = 1/64 (1%) Query: 93 SIFITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRRK 152 F+++++PG +A+ G ++ D I +N + + A E G+ V+L ++R Sbjct: 264 GAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLRNG 322 Query: 153 PPAE 156 P E Sbjct: 323 KPLE 326 Score = 32.5 bits (72), Expect = 0.70, Method: Composition-based stats. Identities = 17/64 (26%), Positives = 30/64 (46%), Gaps = 1/64 (1%) Query: 333 GEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQY 392 G F+S +L G + +G ++ GD I S+NG L + + ++ IA G V + Sbjct: 262 QRGAFVSEVLPGSGSAKAG-VKAGDIITSLNGKPLNSFAELRSRIATTEPGTKVKLGLLR 320 Query: 393 KPEE 396 + Sbjct: 321 NGKP 324 >4D25-A nrPDB Length = 434 Score = 33.7 bits (75), Expect = 0.28, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 38/94 (40%), Gaps = 3/94 (3%) Query: 574 EIDGRDYH-FVSSRE--KMEKDIQAHKFIEAGQYNSHLYGTSVQSVREVAEQGKHCILDV 630 E DG+ FV ++ + + + + + + + + GKHCIL Sbjct: 298 ENDGKRILVFVETKRNADFIAAMLSEQQLLTSSIHGDRMQREREEALQNFKSGKHCILVA 357 Query: 631 SANAVRRLQAAHLHPIAIFIRPRSLENVLEINKR 664 +A A R L ++ + + P+S++ + R Sbjct: 358 TAVAARGLDIKNVDIVVNYDLPKSIDEYVHRIGR 391 >3K50-A nrPDB Length = 403 Score = 33.7 bits (75), Expect = 0.31, Method: Composition-based stats. Identities = 19/115 (16%), Positives = 42/115 (36%), Gaps = 6/115 (5%) Query: 268 LDNEISHSSYLGTDYPTAMTPTSPRRYSPVAKDLLGEEDIPREPRRIVIHRGSTGLGF-- 325 +D+ + D P+ P ++ K + D ++ GF Sbjct: 19 IDSVMRQEYLWYRDMPSPAAPDYFQKPEAFLKKAVASMDNGFSKIDSLLDEPIPSYGFDY 78 Query: 326 ---NIVGGEDGEGIFISFILAGGPADLSGELRKGDQILSVNGVDLRNASHEQAAI 377 ++ + IS+++ G PA+ +G L++G I+ +NG + + Sbjct: 79 TLYKVLDNDTAYNALISYVVPGSPAEEAG-LQRGHWIMMMNGDYITKKVESELLQ 132 Score = 31.4 bits (69), Expect = 1.3, Method: Composition-based stats. Identities = 12/57 (21%), Positives = 26/57 (45%), Gaps = 4/57 (7%) Query: 95 FITKIIPGGAAAQDGRLRVNDSILFVNEVDVREVTHSAAVEALKEAGSIVRLYVMRR 151 I+ ++PG A + G L+ I+ +N +T E L+ + +++ V + Sbjct: 93 LISYVVPGSPAEEAG-LQRGHWIMMMNG---DYITKKVESELLQGSTRQLQIGVYKE 145 >4BNE-A nrPDB Length = 457 Score = 33.7 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 29/146 (19%), Positives = 57/146 (39%), Gaps = 12/146 (8%) Query: 346 PADLSGELRKGDQILSVNGVDLRNASHEQAAIALKNAGQTVTIIAQYKPEEYSRFEAKIH 405 ADL+ L + ++ + +GV L Q + + ++ + K + Y + Sbjct: 316 SADLNRTLSRREKKKASDGVTLTGI--NQTGDQVSQPNKHSSVSSYEKNQSYPTDWSDEE 373 Query: 406 DLREQLMNSSLGSGTA-SLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVID 464 + G ++P +RAL+DY+ + LSF+ GD L ++ Sbjct: 374 SNNPFSSTDAKGDTNPFDEDTSPVMEVRVRALYDYEGQE-----QDELSFKAGDELTKME 428 Query: 465 AGDEEWWQARRVHSDSETDDIGFIPS 490 DE+ W R+ + +G P+ Sbjct: 429 NEDEQGWCKGRL----DNGQVGLYPA 450 >1OV3-A nrPDB Length = 138 Score = 33.3 bits (74), Expect = 0.39, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 11/57 (19%) Query: 434 RALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 RA+ DY+KT ++ GDV+ V++ + WW + G+IP+ Sbjct: 15 RAIADYEKTS-----GSEMALSTGDVVEVVEKSESGWWFCQMKAK------RGWIPA 60 >3HAJ-A nrPDB Length = 486 Score = 32.9 bits (73), Expect = 0.46, Method: Composition-based stats. Identities = 37/163 (22%), Positives = 59/163 (36%), Gaps = 30/163 (18%) Query: 349 LSGELRKGDQILSVNGVDLRNASHEQAAIALKNA-----------GQTVTI---IAQYKP 394 L+G + GDQ L N A A + G TV+ Sbjct: 326 LTGINQTGDQSLPSKPSSTLNVPSNPAQSAQSQSSYNPFEDEDDTGSTVSEKDDTKAKNV 385 Query: 395 EEYSRFEAKIHDLREQLMNSSLGSGTASLRSNPKRGFY-------IRALFDYDKTKDCGF 447 Y + ++ D + N+ S A+ SNP +RAL+DY+ + Sbjct: 386 SSYEKTQSYPTDWSDDESNNPFSSTDANGDSNPFDDDATSGTEVRVRALYDYEGQE---- 441 Query: 448 LSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 LSF+ GD L ++ DE+ W R+ + +G P+ Sbjct: 442 -HDELSFKAGDELTKMEDEDEQGWCKGRL----DNGQVGLYPA 479 >3QWY-A nrPDB Length = 308 Score = 32.5 bits (72), Expect = 0.63, Method: Composition-based stats. Identities = 12/61 (19%), Positives = 25/61 (40%), Gaps = 5/61 (8%) Query: 446 GFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAK 505 G L F G+ L ++ +++WW+AR + G +P+ + E+ + Sbjct: 158 GERETDLPFEQGERLEILSKTNQDWWEAR-----NALGTTGLVPANYVQIQMEFHNDRTS 212 Query: 506 D 506 Sbjct: 213 K 213 >5O2M-A nrPDB Length = 81 Score = 32.5 bits (72), Expect = 0.70, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 20/53 (37%), Gaps = 9/53 (16%) Query: 443 KDCGFLSQALSFRFGDVLHVID---AGDEEWWQARRVHSDSETDDIGFIPSKR 492 + LSFR GD++ V++ G + WW G +P R Sbjct: 15 DNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQ------GIVPGNR 61 >1K4U-S nrPDB Length = 62 Score = 32.1 bits (71), Expect = 0.77, Method: Composition-based stats. Identities = 17/62 (27%), Positives = 29/62 (46%), Gaps = 11/62 (17%) Query: 428 KRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGF 487 K+G + ALF Y+ T+ + L F+ GD++ V+ +EEW + +G Sbjct: 3 KKGSQVEALFSYEATQP-----EDLEFQEGDIILVLSKVNEEWLEGESKGK------VGI 51 Query: 488 IP 489 P Sbjct: 52 FP 53 >1UEC-A nrPDB Length = 193 Score = 32.1 bits (71), Expect = 0.79, Method: Composition-based stats. Identities = 15/57 (26%), Positives = 26/57 (45%), Gaps = 11/57 (19%) Query: 434 RALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPS 490 RA+ DY+KT ++ GDV+ V++ + WW + G+IP+ Sbjct: 15 RAIADYEKTS-----GSEMALSTGDVVEVVEKSESGWWFCQMKAK------RGWIPA 60 >1X69-A nrPDB Length = 79 Score = 32.1 bits (71), Expect = 0.80, Method: Composition-based stats. Identities = 18/65 (27%), Positives = 26/65 (40%), Gaps = 6/65 (9%) Query: 414 SSLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 SS SGT N + AL+DY D +SF D++ I+ D+ WW+ Sbjct: 2 SSGSSGTYDEYENDLGITAV-ALYDYQAAGD-----DEISFDPDDIITNIEMIDDGWWRG 55 Query: 474 RRVHS 478 Sbjct: 56 VCKGR 60 >5O2Q-A nrPDB Length = 99 Score = 31.7 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 13/53 (24%), Positives = 20/53 (37%), Gaps = 9/53 (16%) Query: 443 KDCGFLSQALSFRFGDVLHVID---AGDEEWWQARRVHSDSETDDIGFIPSKR 492 + LSFR GD++ V++ G + WW G +P R Sbjct: 15 DNVAESPDELSFRKGDIMTVLERDTQGLDGWWLCSLHGRQ------GIVPGNR 61 >2YUP-A nrPDB Length = 90 Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 20/67 (29%), Positives = 29/67 (43%), Gaps = 4/67 (5%) Query: 446 GFLSQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAK 505 G L LSFR G+ + +I +E W++ R + + G P+ RE Sbjct: 28 GDLEVELSFRKGEHICLIRKVNENWYEGRITGTGRQ----GIFPASYVQVSREPRLRLCD 83 Query: 506 DWGSSSG 512 D G SSG Sbjct: 84 DSGPSSG 90 >2HSP-A nrPDB Length = 71 Score = 31.0 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 22/48 (45%), Gaps = 5/48 (10%) Query: 426 NPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQA 473 +P ++ALFDY ++ L+F ++ ++ + WW+ Sbjct: 2 SPTFKCAVKALFDYKAQRE-----DELTFIKSAIIQNVEKQEGGWWRG 44 >3J1E-A nrPDB Length = 553 Score = 31.0 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 27/64 (42%), Gaps = 5/64 (7%) Query: 147 YVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSI-----YVTKIIEGGAAH 201 + RK +K++ ++ K PK + I GG+ + ++ V +I+ G A Sbjct: 356 LIEERKVGEDKMVFVEGAKNPKSISILIRGGLERLVDETERALRDALGTVADVIKDGRAI 415 Query: 202 KDGR 205 G Sbjct: 416 AGGG 419 >1WI7-A nrPDB Length = 68 Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 5/45 (11%) Query: 434 RALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHS 478 + F Y D L + GD++ V+ +E WW+ Sbjct: 11 QVAFSYLPQND-----DELELKVGDIIEVVGEVEEGWWEGVLNGK 50 >5XHZ-A nrPDB Length = 66 Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 5/45 (11%) Query: 434 RALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHS 478 + F Y D L + GD++ V+ +E WW+ Sbjct: 13 QVAFSYLPQND-----DELELKVGDIIEVVGEVEEGWWEGVLNGK 52 >2O2O-A nrPDB Length = 92 Score = 30.6 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 10/45 (22%), Positives = 17/45 (37%), Gaps = 5/45 (11%) Query: 434 RALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQARRVHS 478 + F Y D L + GD++ V+ +E WW+ Sbjct: 22 QVAFSYLPQND-----DELELKVGDIIEVVGEVEEGWWEGVLNGK 61 >1UE9-A nrPDB Length = 80 Score = 29.8 bits (65), Expect = 3.9, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 19/60 (31%) Query: 449 SQALSFRFGDVLHVIDAGDEEWWQARRVHSDSETDDIGFIPSKRRVERREWSRLKAKDWG 508 S+ LS G ++ ++ WWQ + F S ++ R G Sbjct: 21 SEQLSLAPGQLILILKKNTSGWWQGELQARGKKRQKGWFPASHVKLLGPSSERASGPSSG 80 >4XCG-B nrPDB Length = 557 Score = 29.8 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%), Gaps = 5/64 (7%) Query: 147 YVMRRKPPAEKVMEIKLIKGPKGLGFSIAGGVGNQHIPGDNSI-----YVTKIIEGGAAH 201 V RK +K++ ++ K PK + I GG+ + ++ V +I G A Sbjct: 358 LVEERKVGEDKMVFVEGAKNPKSVSILIRGGLERVVDETERALRDALGTVADVIRDGRAV 417 Query: 202 KDGR 205 G Sbjct: 418 AGGG 421 >2ED0-A nrPDB Length = 78 Score = 29.4 bits (64), Expect = 5.9, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 28/63 (44%), Gaps = 5/63 (7%) Query: 415 SLGSGTASLRSNPKRGFYIRALFDYDKTKDCGFLSQALSFRFGDVLHVIDAGDEEWWQAR 474 S GS + + A++DY K K+ LSF+ G +++VI D+ W++ Sbjct: 2 SSGSSGDPPWAPRSYLEKVVAIYDYTKDKE-----DELSFQEGAIIYVIKKNDDGWYEGV 56 Query: 475 RVH 477 Sbjct: 57 MNG 59 >1MKM-A nrPDB Length = 249 Score = 29.0 bits (63), Expect = 8.1, Method: Composition-based stats. Identities = 16/102 (15%), Positives = 35/102 (34%), Gaps = 13/102 (12%) Query: 160 EIKLIKGPKGLGFSIAGGVGNQHIPGDNSIYVTKIIEGGAAHKDGRLQIGDKILAVNSV- 218 ++ + + + S++ + + + K KD R G K++ S Sbjct: 23 DVSVSEIAEKFNMSVSNAYKYMVVLEEKGFVLRK--------KDKRYVPGYKLIEYGSFV 74 Query: 219 ----GLEDVMHEDAVAALKNTYDVVYLKVAKPSNAYLSDSYA 256 + D+ H+ V +K T + V+L + D Sbjct: 75 LRRFNIRDIAHDHLVDIMKRTGETVHLILKDGFEGVYIDKVE 116 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.306 0.119 0.295 Lambda K H 0.267 0.0362 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,120,184 Number of Sequences: 36641 Number of extensions: 934266 Number of successful extensions: 3639 Number of sequences better than 10.0: 166 Number of HSP's better than 10.0 without gapping: 200 Number of HSP's successfully gapped in prelim test: 97 Number of HSP's that attempted gapping in prelim test: 2707 Number of HSP's gapped (non-prelim): 639 length of query: 724 length of database: 10,336,785 effective HSP length: 104 effective length of query: 620 effective length of database: 6,526,121 effective search space: 4046195020 effective search space used: 4046195020 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 62 (28.7 bits)