BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P30665 (933 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3JC6-4 nrPDB 1919 0.0 4R7Y-A nrPDB 402 e-112 4FDG-B nrPDB 379 e-105 3F9V-A nrPDB 360 1e-99 5U8S-7 nrPDB 344 9e-95 5BK4-5 nrPDB 333 2e-91 3JC7-2 nrPDB 318 5e-87 5XF8-3 nrPDB 283 2e-76 4R7Z-A nrPDB 276 4e-74 3F8T-A nrPDB 123 3e-28 5B48-B nrPDB 33 0.56 1G8P-A nrPDB 33 0.86 5N1T-A nrPDB 32 1.3 1DOW-A nrPDB 32 1.7 4AIE-A nrPDB 30 3.4 1NY5-A nrPDB 30 3.5 4H9M-A nrPDB 30 5.1 4F19-A nrPDB 30 5.4 5U6P-A nrPDB 30 5.7 3ZKX-A nrPDB 30 5.8 >3JC6-4 nrPDB Length = 933 Score = 1919 bits (4972), Expect = 0.0, Method: Compositional matrix adjust. Identities = 933/933 (100%), Positives = 933/933 (100%) Query: 1 MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG 60 MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG Sbjct: 1 MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG 60 Query: 61 NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS 120 NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS Sbjct: 61 NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS 120 Query: 121 SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII 180 SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII Sbjct: 121 SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII 180 Query: 181 WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN 240 WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN Sbjct: 181 WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN 240 Query: 241 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF 300 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF Sbjct: 241 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF 300 Query: 301 YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI 360 YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI Sbjct: 301 YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI 360 Query: 361 DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY 420 DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY Sbjct: 361 DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY 420 Query: 421 DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST 480 DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST Sbjct: 421 DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST 480 Query: 481 IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI 540 IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI Sbjct: 481 IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI 540 Query: 541 LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600 LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG Sbjct: 541 LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600 Query: 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG 660 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG Sbjct: 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG 660 Query: 661 IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL 720 IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL Sbjct: 661 IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL 720 Query: 721 AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM 780 AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM Sbjct: 721 AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM 780 Query: 781 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP 840 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP Sbjct: 781 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP 840 Query: 841 KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES 900 KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES Sbjct: 841 KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES 900 Query: 901 SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV 933 SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV Sbjct: 901 SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV 933 >4R7Y-A nrPDB Length = 613 Score = 402 bits (1033), Expect = e-112, Method: Compositional matrix adjust. Identities = 244/658 (37%), Positives = 381/658 (57%), Gaps = 65/658 (9%) Query: 193 NFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYK 252 ++R+ + F F+ NN ++ YI+++NE+ +L ++ ++L++ Sbjct: 10 DYRDVFIEFLTTFKG---------NNNQNK---YIERINELVAYRKKSLIIEFSDVLSF- 56 Query: 253 QTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCK 312 E+L ++++N + ++ I++ + D ++ L D D++++ VR + Sbjct: 57 -NENLAYEIINNTKIILPILEGALYDHILQL--DPTYQRDIEKVH-----VRIVGIPRVI 108 Query: 313 GMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRG-----VIQE 367 +R++ DI KLI + G++++ TPV + A +K D E V++ Sbjct: 109 ELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEM 168 Query: 368 PARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSC 427 P C + C +P LI + D Q +QE P+ VP GQ P + + + D+LVDS Sbjct: 169 PTICPK--CGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSA 226 Query: 428 RAGDRIEVTGTF---RSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQE 484 R GDR++VTG + P++ SR +++ Y+ V ++ VS K L QE Sbjct: 227 RPGDRVKVTGILDIKQDSPVKRGSR-----AVFDIYMKVSSIE-VSQKVL--------QE 272 Query: 485 LMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQL 544 L +I+ ++ I+E+A R+D+ + SIAP+IY ++VKKGI L L Sbjct: 273 L--------------EISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALAL 318 Query: 545 FGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604 FGG ++ G R RGDI++LL GDP +KSQIL+YV + PR +YTSGK SSA GLTA Sbjct: 319 FGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAA 378 Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 RD T VLE+GALVL+DGG IDE DKMSD RSV+HE +EQQTISI+KAGI T Sbjct: 379 AVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITAT 438 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHL 724 LNAR++++A+ANP R+N E IDLPP LLSRFDL+++++D+ D+K D E+A+H+ Sbjct: 439 LNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHI 498 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 + + E ++ +P E L YI+YA+++IHP+I+E A E+ + YV MRK + Sbjct: 499 LRVR-RGESEVVAPK--IPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKT 555 Query: 785 RSDEKRITA---TTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATD 839 + +E+ I T RQLE++IRL+EAHA+M+L +V ED +EA++L+ +K A D Sbjct: 556 KGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAMD 613 >4FDG-B nrPDB Length = 692 Score = 379 bits (972), Expect = e-105, Method: Compositional matrix adjust. Identities = 243/730 (33%), Positives = 414/730 (56%), Gaps = 77/730 (10%) Query: 193 NFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYK 252 ++R+ + F F+ NN ++ YI+++NE+ +L ++ ++L++ Sbjct: 15 DYRDVFIEFLTTFKG---------NNNQNK---YIERINELVAYRKKSLIIEFSDVLSF- 61 Query: 253 QTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCK 312 E+L ++++N + ++ I++ + D ++ L D D++++ VR + Sbjct: 62 -NENLAYEIINNTKIILPILEGALYDHILQL--DPTYQRDIEKVH-----VRIVGIPRVI 113 Query: 313 GMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRG-----VIQE 367 +R++ DI KLI + G++++ TPV + A +K D E V++ Sbjct: 114 ELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEM 173 Query: 368 PARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSC 427 P C + C +P LI + D Q +QE P+ VP GQ P + + + D+LVDS Sbjct: 174 PTICPK--CGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSA 231 Query: 428 RAGDRIEVTGTF---RSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQE 484 R GDR++VTG + P++ SR +++ Y+ V ++ VS K LD E Sbjct: 232 RPGDRVKVTGILDIKQDSPVKRGSR-----AVFDIYMKVSSIE-VSQKVLD--------E 277 Query: 485 LMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQL 544 ++ I+++D KI+++A + + SIAPSIY ++K+ + L L Sbjct: 278 VI--------------ISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 323 Query: 545 FGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604 FGG K + R RGDI+IL+ GDP T+KSQ+LQ++ ++ PR VYT+GKGS+A GLTA Sbjct: 324 FGGVPKVL-EDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 382 Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 + R+ T + LE+GALVL+DGG+ IDE DKM D R +HE MEQQT+SIAKAGI+ Sbjct: 383 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 442 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHL 724 LNAR++++A+ NP RY PV++NI+LPP +LSRFDL++++ D+ E+ DRELA ++ Sbjct: 443 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQ-DRELANYI 501 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 +++ S +++ ++ L YI+YA++++ P IT AK + +V MRK S Sbjct: 502 LDVH-----SGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRK--KSS 554 Query: 785 RSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGK 844 + + I T RQLE++IR++EA+AKM LK V ED + A+ ++R ++ D ++GK Sbjct: 555 ETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDMESGK 614 Query: 845 IDMNLVQTGKSVIQRKLQEDLSR--EIMNVLKDQASDSMSFNELIKQINEHSQDRVESSD 902 ID++ + TGK + +E + + EI++ L +S+ +++K E Q +E S+ Sbjct: 615 IDIDTIMTGKP---KSAREKMMKIIEIIDSLA-VSSECAKVKDILK---EAQQVGIEKSN 667 Query: 903 IQEALSRLQQ 912 I++ L+ +++ Sbjct: 668 IEKLLTDMRK 677 >3F9V-A nrPDB Length = 595 Score = 360 bits (924), Expect = 1e-99, Method: Compositional matrix adjust. Identities = 223/646 (34%), Positives = 368/646 (56%), Gaps = 68/646 (10%) Query: 193 NFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYK 252 ++R+ + F F+ NN ++ YI+++NE+ +L ++ ++L++ Sbjct: 3 DYRDVFIEFLTTFKG---------NNNQNK---YIERINELVAYRKKSLIIEFSDVLSF- 49 Query: 253 QTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCK 312 E+L ++++N + ++ I++ + D ++ L D D++++ VR + Sbjct: 50 -NENLAYEIINNTKIILPILEGALYDHILQL--DPTYQRDIEKVH-----VRIVGIPRVI 101 Query: 313 GMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRG-----VIQE 367 +R++ DI KLI + G++++ TPV + A +K D E V++ Sbjct: 102 ELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEM 161 Query: 368 PARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSC 427 P C + C +P LI + D Q +QE P+ VP GQ P + + + D+LVDS Sbjct: 162 PTICPK--CGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSA 219 Query: 428 RAGDRIEVTGTF---RSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQE 484 R GDR++VTG + P++ SR +++ Y+ V ++ VS K LD E Sbjct: 220 RPGDRVKVTGILDIKQDSPVKRGSR-----AVFDIYMKVSSIE-VSQKVLD--------E 265 Query: 485 LMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQL 544 ++ I+++D KI+++A + + SIAPSIY ++K+ + L L Sbjct: 266 VI--------------ISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 311 Query: 545 FGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604 FGG K + R RGDI+IL+ GDP T+KSQ+LQ++ ++ PR VYT+GKGS+A GLTA Sbjct: 312 FGGVPKVL-EDTRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 370 Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 + R+ T + LE+GALVL+DGG+ IDE DKM D R +HE MEQQT+SIAKAGI+ Sbjct: 371 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 430 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHL 724 LNAR++++A+ NP RY PV++NI+LPP +LSRFDL++++ D+ E+ DRELA ++ Sbjct: 431 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQ-DRELANYI 489 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 +++ S +++ ++ L YI+YA++++ P IT AK + +V MRK S Sbjct: 490 LDVH-----SGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRK--KSS 542 Query: 785 RSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIR 830 + + I T RQLE++IR++EA+AKM LK V ED + A+ ++R Sbjct: 543 ETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMR 588 >5U8S-7 nrPDB Length = 845 Score = 344 bits (883), Expect = 9e-95, Method: Compositional matrix adjust. Identities = 219/561 (39%), Positives = 335/561 (59%), Gaps = 44/561 (7%) Query: 314 MRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCER 373 +R++ + + +LI ++G++ R + V P ++V + C+ C + + E++ + C Sbjct: 227 VRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTS 286 Query: 374 IDC--NEPNSMSLIHNRCS-FADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAG 430 +C N+ + R S F+ Q K+QE VP G P S+++ V LV S G Sbjct: 287 EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPG 346 Query: 431 DRIEVTGTFRSIPIRANSRQRVLKS--LYKTYVDVVHVKKVSDKRLDVD-TSTIEQELMQ 487 D ++VTG F P + LK+ L +TY++ V++ K TS +E+ +M Sbjct: 347 DIVDVTGIFLPAPYTGF---KALKAGLLTETYLEAQFVRQHKKKFASFSLTSDVEERVM- 402 Query: 488 NKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGG 547 E+ D+Y+ LA+SIAP IY DVKK +LL L GG Sbjct: 403 -----------------------ELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGG 439 Query: 548 TNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITR 607 +K G + RGDIN+ L GDP +KSQ+L+ + KI+PRGVYT+GKGSS VGLTA + + Sbjct: 440 VDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMK 499 Query: 608 DVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNA 667 D T +++LE GALVL+D G+CCIDEFDKM +S R+ +HEVMEQQTISI+KAGI TTLNA Sbjct: 500 DPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNA 559 Query: 668 RSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNL 727 R+SILA+ANP+ RYNP L +NI+LP LLSRFD+++L+LD +D +LA+H+T + Sbjct: 560 RTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYV 619 Query: 728 YLEDKPEHISQDDVLPVEFLTM--YISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSR 785 ++ +K + D PVE M YI+YAK P+++EA +V+AY+ +R+ D R Sbjct: 620 HMHNKQPDL---DFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQ--DSKR 673 Query: 786 SDEKRIT---ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKT 842 + + + AT R L +IRL++A AK++L ++V+++DV+EA+RL+R + + + Sbjct: 674 EMDSKFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNK 733 Query: 843 GKIDMNLVQTGKSVIQRKLQE 863 K D + ++I++ LQE Sbjct: 734 SKEDESPTTKIFTIIKKMLQE 754 >5BK4-5 nrPDB Length = 775 Score = 333 bits (854), Expect = 2e-91, Method: Compositional matrix adjust. Identities = 231/765 (30%), Positives = 384/765 (50%), Gaps = 111/765 (14%) Query: 189 ECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNL 248 E +F+NF++ F+ D + Y QL + +L ++ +L Sbjct: 26 EIIKSFKNFILEFRL-----------------DSQFIYRDQLRNNILVKNYSLTVNMEHL 68 Query: 249 LAYKQTEDLYHQLLNYPQEVISIMDQTIKDCM--VSLI-----VDNN--------LDYD- 292 + Y ED+Y +L + P ++I + + I +S++ +NN +D D Sbjct: 69 IGYN--EDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDS 126 Query: 293 --LDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCN 350 L+ + T F + N +R+L+ + K++ L G+++ ++ + C Sbjct: 127 LLLNSLPT-FQLILNSNANQIP-LRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCR 184 Query: 351 VCDHTMAVEIDR------GVIQEPARC------ERIDCNE-------------PNSMSLI 385 C HT ++ I+ + P C E NE P+ +I Sbjct: 185 NCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIII 244 Query: 386 HNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIR 445 H F D+Q +KLQE P+ VP G+ P ++++ L + G R+ + G + SI Sbjct: 245 HESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY-SIYNS 303 Query: 446 ANSRQRVLK---------SLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVE 496 N ++ Y+ ++ ++ DV+TS+I Sbjct: 304 KNGAGSGRSGGGNGGSGVAIRTPYIKILGIQS------DVETSSIWN------------- 344 Query: 497 EVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGG 556 V T+++ + +++ LY +L SIAPSI+ ED+KK I+ L GG+ K G Sbjct: 345 SVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGM 404 Query: 557 RYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVL 616 R RGDIN+LL GDP T+KSQ+L++V K++P VYTSGKGSSA GLTA + RD T++ L Sbjct: 405 RLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYL 464 Query: 617 ESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASAN 676 E GA+VL+DGGV CIDEFDKM D R +HE MEQQTISIAKAGI T LN+R+S+LA+AN Sbjct: 465 EGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAAN 524 Query: 677 PIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHI 736 PI RY+ +NID +LSRFD++++V D +E+ D +A H+ N++ + Sbjct: 525 PIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQ 584 Query: 737 SQDD----VLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRK---MGDDSRSDEK 789 +Q + + +E + YI+Y + P ++ A +L +V +RK + + ++ Sbjct: 585 NQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERS 644 Query: 790 RITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNL 849 I T RQLE++IR+ E+ AK++L + + V EA+RL +++ D A+ G ++ Sbjct: 645 SIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQ-- 702 Query: 850 VQTGKSVIQ-RKLQEDLSREI-------MNVLKDQASDSMSFNEL 886 +G S+ + R+ +++L R + L+ + D+ F++L Sbjct: 703 -ASGTSLSEIRRFEQELKRRLPIGWSTSYQTLRREFVDTHRFSQL 746 >3JC7-2 nrPDB Length = 868 Score = 318 bits (816), Expect = 5e-87, Method: Compositional matrix adjust. Identities = 214/680 (31%), Positives = 341/680 (50%), Gaps = 87/680 (12%) Query: 206 RKILDEREEFINNTTDE--ELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLN 263 R I E + F+ TDE Y ++ + E+ + +L ++ R+L K L+ L Sbjct: 205 RTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALF--LAK 262 Query: 264 YPQEVISIMDQTIKDCMVSLIVDNNLDY-DLDEIETKFYKVRPYNVGSCKGMRELNPNDI 322 P+E++ I D + L Y D I ++ + VR + + +REL +++ Sbjct: 263 CPEEMLKIFDLVAMEA-------TELHYPDYARIHSEIH-VRISDFPTIYSLRELRESNL 314 Query: 323 DKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERI----DCNE 378 L+ + G+V R T V P +K F C C + Q+ RI +C Sbjct: 315 SSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILG-----PFFQDSNEEIRISFCTNCKS 369 Query: 379 PNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGT 438 + + + + Q + LQE P VP G+ P + + +LVD + G+ +EVTG Sbjct: 370 KGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGI 429 Query: 439 FRSIPIRANSRQRVL--KSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVE 496 ++ N+ L K+ + + ++ + KR + +T+ +E + Sbjct: 430 YK------NNYDGNLNAKNGFPVFATIIEANSI--KRREGNTANEGEEGL---------- 471 Query: 497 EVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGG 556 +V T+++ + R+++ + + S+APSIY D+K + LFGG K Sbjct: 472 DVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKH 531 Query: 557 RYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVL 616 RGDIN+LL GDP T+KSQIL+YV K R V+ +G+G+SAVGLTA + +D TK+ L Sbjct: 532 SIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTL 591 Query: 617 ESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASAN 676 E GALVL+D GVC IDEFDKM+D R+ +HE MEQQ+ISI+KAGI+TTL AR SI+A+AN Sbjct: 592 EGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAAN 651 Query: 677 PIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEH- 735 P G RYN LP+ +N+ L P+LSRFD++ +V D VDE+ D LA + + ++ PE+ Sbjct: 652 PNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPEND 711 Query: 736 -----------------ISQDDV-----------------------LPVEFLTMYISYAK 755 +D++ +P E L YI YA+ Sbjct: 712 EDREGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYAR 771 Query: 756 EHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKN 815 I+P + + ++ R Y +R+ + S T R LES++R+AE+ AKM+L Sbjct: 772 TKIYPKLHQMDMDKVSRVYADLRRESISTGS----FPITVRHLESILRIAESFAKMRLSE 827 Query: 816 VVELEDVQEAVRLIRSAIKD 835 V D+ A++++ + D Sbjct: 828 FVSSYDLDRAIKVVVDSFVD 847 >5XF8-3 nrPDB Length = 997 Score = 283 bits (725), Expect = 2e-76, Method: Compositional matrix adjust. Identities = 201/588 (34%), Positives = 304/588 (51%), Gaps = 88/588 (14%) Query: 315 RELNPNDIDKLINLKGLVLRSTPVIPDM------KVAFFKCNVCDHTMAVEIDRGVIQEP 368 R L ++KL++++G+V +++ V P + + + D+T A I P Sbjct: 195 RTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRDYTDATTTLTTRIPTP 254 Query: 369 ARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCR 428 A D E N ++ + +F D Q I +QE P+ P GQ P SI + + D+LVD + Sbjct: 255 AIYPTEDT-EGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTK 313 Query: 429 AGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQN 488 GDR+ V G F+S+ ++ S+ + T + + Sbjct: 314 PGDRVNVVGVFKSLGAGGMNQSN------------------SNTLIGFKTLILGNTVYPL 355 Query: 489 KVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGT 548 V + +TD D+ I +++ ++D++ +L++S+APSIY + +KK ILL L GG Sbjct: 356 HARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGV 415 Query: 549 NKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRD 608 K G RGDINIL+ GDPST+KSQ+L++V + T+G+GSS VGLTA +T D Sbjct: 416 EKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTD 475 Query: 609 VDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNAR 668 +T + LE+GA+VL+D GV CIDEFDKM+D R +HEVMEQQT++IAKAGI TTLNAR Sbjct: 476 RETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNAR 535 Query: 669 SSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKH----- 723 S++A+ANP+ +Y+ N +NI LP LLSRFDL+++V D ++E DR +++H Sbjct: 536 CSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTH 595 Query: 724 --LTNLYLEDKPEH--------ISQD-DVLPVEFLTMYIS----------YAKEHIHPII 762 L YLE +P + +D D+ P E + E +P++ Sbjct: 596 RYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLL 655 Query: 763 TEAAK----------TEL--------VRAYVG-----------------MRKMGDDSRSD 787 AK TE+ +R YV + K D R+D Sbjct: 656 QAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRND 715 Query: 788 E--KRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAI 833 + K+ T R LE++IRLA AHAK++L V D + A L+R A+ Sbjct: 716 DNTKKSPITARTLETLIRLATAHAKVRLSKTVNKVDAKVAANLLRFAL 763 >4R7Z-A nrPDB Length = 338 Score = 276 bits (705), Expect = 4e-74, Method: Compositional matrix adjust. Identities = 146/334 (43%), Positives = 209/334 (62%), Gaps = 6/334 (1%) Query: 509 IREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCG 568 I+E+A R+D+ + SIAP+IY ++VKKGI L LFGG ++ G R RGDI++LL G Sbjct: 8 IKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVG 67 Query: 569 DPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGV 628 DP +KSQIL+YV + PR +YTS GG Sbjct: 68 DPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXGGY 127 Query: 629 CCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPV 688 IDE DKMSD RSV+HE +EQQTISI+KAGI TLNAR++++A+ANP R+N Sbjct: 128 ALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFNRMKNP 187 Query: 689 TENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLT 748 E IDLPP LLSRFDL+++++D+ D+K D E+A+H+ + + E ++ +P E L Sbjct: 188 FEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVR-RGESEVVAPK--IPHEILR 244 Query: 749 MYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITA---TTRQLESMIRLA 805 YI+YA+++IHP+I+E A E+ + YV MRK ++ +E+ I T RQLE++IRL+ Sbjct: 245 KYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALIRLS 304 Query: 806 EAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATD 839 EAHA+M+L +V ED +EA++L+ +K A D Sbjct: 305 EAHARMRLSPIVTREDAREAIKLMEYTLKQIAMD 338 >3F8T-A nrPDB Length = 506 Score = 123 bits (309), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 115/349 (32%), Positives = 170/349 (48%), Gaps = 64/349 (18%) Query: 491 DHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNK 550 D E+EE R++ D+D + AR+IAP + E+V K + LQLF K Sbjct: 189 DPAELEEFRELADKDP------------LTTFARAIAP-LPGAEEVGKMLALQLFSCVGK 235 Query: 551 TFTKGGRYRGDINILLCGDPSTSKSQILQYV-HKITPRGVYTSGKGSSAVGLTAYITRDV 609 + +++LL G P S+IL +V + PRGVY + + LTA + D Sbjct: 236 NSER-------LHVLLAGYPVVC-SEILHHVLDHLAPRGVYVDLRRTELTDLTAVLKED- 286 Query: 610 DTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARS 669 + L +GA VL+DGG+ +D + + R L E M++ T+++ GI LNAR Sbjct: 287 --RGWALRAGAAVLADGGILAVDHLEGAPEPHRWALMEAMDKGTVTVD--GI--ALNARC 340 Query: 670 SILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYL 729 ++LA+ NP G ++ P+ P IDL LS FDL+ + VD + Sbjct: 341 AVLAAINP-GEQW-PSDPPIARIDLDQDFLSHFDLIAFL--GVDPRPG------------ 384 Query: 730 EDKPEHISQDDVLP-VEFLTMYISYA-KEHIHPIITEAAKTELVRAYVGMRK-------M 780 +PE QD +P L Y+ YA +EH P +TE A+ L Y R+ M Sbjct: 385 --EPE--EQDTEVPSYTLLRRYLLYAIREHPAPELTEEARKRLEHWYETRREEVEERLGM 440 Query: 781 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLI 829 G + + T RQLES+ RLA+AHA+M+L + VE EDV A L+ Sbjct: 441 GLPT------LPVTRRQLESVERLAKAHARMRLSDDVEPEDVDIAAELV 483 >5B48-B nrPDB Length = 305 Score = 33.1 bits (74), Expect = 0.56, Method: Composition-based stats. Identities = 27/105 (25%), Positives = 51/105 (48%), Gaps = 3/105 (2%) Query: 387 NRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIRA 446 N + DK++ KL PD+ P + P ++ + + S GDRI + G F + Sbjct: 204 NTKEWYDKRIYKLDTLPDWDPVVKKPEEVNEKIKRAIDKSLEWGDRIPI-GIFYQNELVP 262 Query: 447 NSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVD 491 + +R+ K+ Y+D K++ +K + T+ I+ L + +VD Sbjct: 263 SYEERI-KANSPAYLDYTPAKQLIEKEGKL-TTIIDPLLKEREVD 305 >1G8P-A nrPDB Length = 350 Score = 32.7 bits (73), Expect = 0.86, Method: Compositional matrix adjust. Identities = 30/109 (27%), Positives = 44/109 (40%), Gaps = 12/109 (11%) Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 I R + + E G L ++ G IDE + + D +L +V + + + G+ Sbjct: 124 IERAISKGEKAFEPGLLARANRGYLYIDECNLLEDHIVDLLLDVAQSGENVVERDGLSIR 183 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVD 713 AR ++ S NP E DL P LL RF L VL D Sbjct: 184 HPARFVLVGSGNP------------EEGDLRPQLLDRFGLSVEVLSPRD 220 >5N1T-A nrPDB Length = 429 Score = 32.0 bits (71), Expect = 1.3, Method: Compositional matrix adjust. Identities = 14/54 (25%), Positives = 30/54 (55%), Gaps = 1/54 (1%) Query: 510 REVAAREDLYSLLARSIAPSIYE-LEDVKKGILLQLFGGTNKTFTKGGRYRGDI 562 ++ A++ L+ ++ P + E + ++ G + ++ T + FT GRYRGD+ Sbjct: 227 KDAFAKQGLFQTGWETLYPGMIEWVPGIEGGTVERVDAATGEVFTPSGRYRGDV 280 >1DOW-A nrPDB Length = 205 Score = 31.6 bits (70), Expect = 1.7, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 38/65 (58%) Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQT 852 AT LE ++A+ +K + VV +EDV++ L++SA ++A DP + N+V+ Sbjct: 12 ATENFLEKGDKIAKESQFLKEELVVAVEDVRKQGDLMKSAAGEFADDPCSSVKRGNMVRA 71 Query: 853 GKSVI 857 ++++ Sbjct: 72 ARALL 76 >4AIE-A nrPDB Length = 549 Score = 30.4 bits (67), Expect = 3.4, Method: Compositional matrix adjust. Identities = 22/77 (28%), Positives = 39/77 (50%), Gaps = 13/77 (16%) Query: 200 SFKYKFRKILDEREE----------FINNTTDEELYYIKQLNEMRELGTSNLNLDARNLL 249 S Y ++K++ R E ++NT D L Y + LN+ + L +NL+ + +N + Sbjct: 447 SIFYTYQKLIKLRHENPIVVDGDFSLVSNTQDAVLAYYRILNDKKWLVVANLSNEEQNFV 506 Query: 250 AYKQTEDLYHQLLNYPQ 266 + Q E + L NYP+ Sbjct: 507 SNDQIETI---LSNYPE 520 >1NY5-A nrPDB Length = 387 Score = 30.4 bits (67), Expect = 3.5, Method: Compositional matrix adjust. Identities = 31/126 (24%), Positives = 51/126 (40%), Gaps = 21/126 (16%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGL-TAYITRDVDTKQLV-LESGAL 621 +L+ G+ K + + +HK++ R V L A I RD+ +L E GA Sbjct: 163 VLITGESGVGKEVVARLIHKLSDRS------KEPFVALNVASIPRDIFEAELFGYEKGAF 216 Query: 622 V-----------LSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSS 670 L+DGG +DE ++S ++ L V+E + G + Sbjct: 217 TGAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVR 274 Query: 671 ILASAN 676 ILA+ N Sbjct: 275 ILAATN 280 >4H9M-A nrPDB Length = 840 Score = 30.0 bits (66), Expect = 5.1, Method: Compositional matrix adjust. Identities = 28/99 (28%), Positives = 49/99 (49%), Gaps = 7/99 (7%) Query: 809 AKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSRE 868 A+ +L V L + EAV LI S I +YA D + K L+ G+ ++ R+ Sbjct: 20 AQKRLARGVRL-NYTEAVALIASQIMEYARDGE--KTVAQLMCLGQHLLGRRQVLPAVPH 76 Query: 869 IMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEAL 907 ++N ++ +A +F + K + H E+ ++QEAL Sbjct: 77 LLNAVQVEA----TFPDGTKLVTVHDPISRENGELQEAL 111 >4F19-A nrPDB Length = 381 Score = 30.0 bits (66), Expect = 5.4, Method: Compositional matrix adjust. Identities = 15/41 (36%), Positives = 25/41 (60%), Gaps = 5/41 (12%) Query: 48 GRN---NSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDVF 85 G+N N+Q +S N+ AAIG+ P+ P+++ R N D + Sbjct: 230 GKNVATNTQGVSPAAANVSAAIGAVPV--PAAADRSNPDAW 268 >5U6P-A nrPDB Length = 660 Score = 29.6 bits (65), Expect = 5.7, Method: Compositional matrix adjust. Identities = 35/134 (26%), Positives = 66/134 (49%), Gaps = 21/134 (15%) Query: 779 KMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYAT 838 K+ D S E + R+ S +R A+ + ++ +V +V E ++R A + A Sbjct: 531 KLTDGSYFGEICLLTKGRRTAS-VR-ADTYCRLYSLSVDNFNEVLEEYPMMRRAFETVAI 588 Query: 839 DPKTGKIDMNLVQTGK--SVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQD 896 D L + GK S++ +K Q+DL+ + N +Q NE++KQI +H ++ Sbjct: 589 D--------RLDRIGKKNSILLQKFQKDLNTGVFN---NQE------NEILKQIVKHDRE 631 Query: 897 RVESSDIQEALSRL 910 V+++ +E+ S L Sbjct: 632 MVQAALPRESSSVL 645 >3ZKX-A nrPDB Length = 386 Score = 29.6 bits (65), Expect = 5.8, Method: Compositional matrix adjust. Identities = 19/48 (39%), Positives = 26/48 (54%), Gaps = 1/48 (2%) Query: 222 EELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVI 269 EE YY ++ ++ E+G +LNLD R A K D LL PQ+V Sbjct: 196 EEWYYQIEILKL-EIGGQSLNLDCREYNADKAIVDSGTTLLRLPQKVF 242 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3JC6-4 nrPDB 1366 0.0 4FDG-B nrPDB 840 0.0 4R7Y-A nrPDB 795 0.0 3F9V-A nrPDB 775 0.0 5BK4-5 nrPDB 687 0.0 3JC7-2 nrPDB 659 0.0 5U8S-7 nrPDB 577 e-165 5XF8-3 nrPDB 541 e-154 4R7Z-A nrPDB 425 e-119 3F8T-A nrPDB 312 4e-85 Sequences not found previously or not previously below threshold: 2R44-A nrPDB 41 0.003 5EXS-A nrPDB 39 0.008 4QHS-A nrPDB 39 0.010 5EXX-A nrPDB 38 0.016 3DZD-A nrPDB 37 0.030 1OFI-A nrPDB 37 0.035 1NY5-A nrPDB 37 0.042 4LZZ-A nrPDB 37 0.049 3M6A-A nrPDB 36 0.060 1IN6-A nrPDB 36 0.11 4L4U-A nrPDB 36 0.11 4F19-A nrPDB 35 0.14 3K1J-A nrPDB 35 0.15 4ZPX-A nrPDB 35 0.15 2R65-A nrPDB 35 0.17 4YPL-A nrPDB 34 0.24 1QVR-A nrPDB 34 0.27 2IY3-A nrPDB 34 0.33 1RJ9-B nrPDB 34 0.43 4YPN-A nrPDB 33 0.47 1OJL-A nrPDB 33 0.49 4BS1-B nrPDB 33 0.53 2FFH-A nrPDB 33 0.59 4PEK-A nrPDB 33 0.65 6ED3-A nrPDB 33 0.74 4I5O-A nrPDB 33 0.76 4PA8-A nrPDB 32 0.83 1HQC-A nrPDB 32 0.84 1F5N-A nrPDB 32 0.84 4ZXZ-A nrPDB 32 1.2 2ISS-A nrPDB 32 1.3 4LT9-A nrPDB 32 1.4 3IFE-A nrPDB 31 2.3 5AOU-A nrPDB 31 2.5 1UM8-A nrPDB 31 2.6 2Q8F-A nrPDB 31 2.8 4HSE-A nrPDB 31 2.9 3U5Z-B nrPDB 31 2.9 1RWG-A nrPDB 31 3.7 2GGM-A nrPDB 30 4.8 4IJB-A nrPDB 30 5.1 4WV3-A nrPDB 30 5.9 4OWW-B nrPDB 29 7.6 CONVERGED! >3JC6-4 nrPDB Length = 933 Score = 1366 bits (3535), Expect = 0.0, Method: Composition-based stats. Identities = 933/933 (100%), Positives = 933/933 (100%) Query: 1 MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG 60 MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG Sbjct: 1 MSQQSSSPTKEDNNSSSPVVPNPDSVPPQLSSPALFYSSSSSQGDIYGRNNSQNLSQGEG 60 Query: 61 NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS 120 NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS Sbjct: 61 NIRAAIGSSPLNFPSSSQRQNSDVFQSQGRQGRIRSSASASGRSRYHSDLRSDRALPTSS 120 Query: 121 SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII 180 SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII Sbjct: 121 SSLGRNGQNRVHMRRNDIHTSDLSSPRRIVDFDTRSGVNTLDTSSSSAPPSEASEPLRII 180 Query: 181 WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN 240 WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN Sbjct: 181 WGTNVSIQECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSN 240 Query: 241 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF 300 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF Sbjct: 241 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKF 300 Query: 301 YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI 360 YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI Sbjct: 301 YKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEI 360 Query: 361 DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY 420 DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY Sbjct: 361 DRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVY 420 Query: 421 DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST 480 DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST Sbjct: 421 DELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTST 480 Query: 481 IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI 540 IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI Sbjct: 481 IEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGI 540 Query: 541 LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600 LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG Sbjct: 541 LLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVG 600 Query: 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG 660 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG Sbjct: 601 LTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAG 660 Query: 661 IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL 720 IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL Sbjct: 661 IITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDREL 720 Query: 721 AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM 780 AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM Sbjct: 721 AKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKM 780 Query: 781 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP 840 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP Sbjct: 781 GDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDP 840 Query: 841 KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES 900 KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES Sbjct: 841 KTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVES 900 Query: 901 SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV 933 SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV Sbjct: 901 SDIQEALSRLQQEDKVIVLGEGVRRSVRLNNRV 933 >4FDG-B nrPDB Length = 692 Score = 840 bits (2170), Expect = 0.0, Method: Composition-based stats. Identities = 243/730 (33%), Positives = 413/730 (56%), Gaps = 77/730 (10%) Query: 193 NFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYK 252 ++R+ + F F+ NN ++ YI+++NE+ +L ++ ++L++ Sbjct: 15 DYRDVFIEFLTTFKG---------NNNQNK---YIERINELVAYRKKSLIIEFSDVLSF- 61 Query: 253 QTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCK 312 E+L ++++N + ++ I++ + D ++ L D D++++ VR + Sbjct: 62 -NENLAYEIINNTKIILPILEGALYDHILQL--DPTYQRDIEKVH-----VRIVGIPRVI 113 Query: 313 GMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRG-----VIQE 367 +R++ DI KLI + G++++ TPV + A +K D E V++ Sbjct: 114 ELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEM 173 Query: 368 PARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSC 427 P C + C +P LI + D Q +QE P+ VP GQ P + + + D+LVDS Sbjct: 174 PTICPK--CGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSA 231 Query: 428 RAGDRIEVTGTF---RSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQE 484 R GDR++VTG + P++ SR +++ Y+ V ++ VS K LD E Sbjct: 232 RPGDRVKVTGILDIKQDSPVKRGSR-----AVFDIYMKVSSIE-VSQKVLD--------E 277 Query: 485 LMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQL 544 ++ I+++D KI+++A + + SIAPSIY ++K+ + L L Sbjct: 278 VI--------------ISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 323 Query: 545 FGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604 FGG K R RGDI+IL+ GDP T+KSQ+LQ++ ++ PR VYT+GKGS+A GLTA Sbjct: 324 FGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 382 Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 + R+ T + LE+GALVL+DGG+ IDE DKM D R +HE MEQQT+SIAKAGI+ Sbjct: 383 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 442 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHL 724 LNAR++++A+ NP RY PV++NI+LPP +LSRFDL++++ D+ E+ DRELA ++ Sbjct: 443 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQ-DRELANYI 501 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 +++ S +++ ++ L YI+YA++++ P IT AK + +V MRK S Sbjct: 502 LDVH-----SGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRK--KSS 554 Query: 785 RSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGK 844 + + I T RQLE++IR++EA+AKM LK V ED + A+ ++R ++ D ++GK Sbjct: 555 ETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVGVDMESGK 614 Query: 845 IDMNLVQTGKSVIQRKLQEDLSR--EIMNVLKDQASDSMSFNELIKQINEHSQDRVESSD 902 ID++ + TGK + +E + + EI++ L +S+ +++K E Q +E S+ Sbjct: 615 IDIDTIMTGKP---KSAREKMMKIIEIIDSLA-VSSECAKVKDILK---EAQQVGIEKSN 667 Query: 903 IQEALSRLQQ 912 I++ L+ +++ Sbjct: 668 IEKLLTDMRK 677 >4R7Y-A nrPDB Length = 613 Score = 795 bits (2052), Expect = 0.0, Method: Composition-based stats. Identities = 241/658 (36%), Positives = 379/658 (57%), Gaps = 65/658 (9%) Query: 193 NFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYK 252 ++R+ + F F+ NN ++ YI+++NE+ +L ++ ++L++ Sbjct: 10 DYRDVFIEFLTTFKG---------NNNQNK---YIERINELVAYRKKSLIIEFSDVLSF- 56 Query: 253 QTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCK 312 E+L ++++N + ++ I++ + D ++ L D D++++ VR + Sbjct: 57 -NENLAYEIINNTKIILPILEGALYDHILQL--DPTYQRDIEKVH-----VRIVGIPRVI 108 Query: 313 GMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRG-----VIQE 367 +R++ DI KLI + G++++ TPV + A +K D E V++ Sbjct: 109 ELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEM 168 Query: 368 PARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSC 427 P C + C +P LI + D Q +QE P+ VP GQ P + + + D+LVDS Sbjct: 169 PTICPK--CGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSA 226 Query: 428 RAGDRIEVTGTF---RSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQE 484 R GDR++VTG + P++ SR +++ Y+ V ++ VS K L Sbjct: 227 RPGDRVKVTGILDIKQDSPVKRGSR-----AVFDIYMKVSSIE-VSQKVL---------- 270 Query: 485 LMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQL 544 + +I+ ++ I+E+A R+D+ + SIAP+IY ++VKKGI L L Sbjct: 271 ------------QELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALAL 318 Query: 545 FGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604 FGG ++ G R RGDI++LL GDP +KSQIL+YV + PR +YTSGK SSA GLTA Sbjct: 319 FGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSSSAAGLTAA 378 Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 RD T VLE+GALVL+DGG IDE DKMSD RSV+HE +EQQTISI+KAGI T Sbjct: 379 AVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITAT 438 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHL 724 LNAR++++A+ANP R+N E IDLPP LLSRFDL+++++D+ D+K D E+A+H+ Sbjct: 439 LNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHI 498 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 + + E ++ +P E L YI+YA+++IHP+I+E A E+ + YV MRK + Sbjct: 499 LRVR-RGESEVVAPK--IPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKT 555 Query: 785 RSDEK---RITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATD 839 + +E+ I T RQLE++IRL+EAHA+M+L +V ED +EA++L+ +K A D Sbjct: 556 KGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAMD 613 >3F9V-A nrPDB Length = 595 Score = 775 bits (2000), Expect = 0.0, Method: Composition-based stats. Identities = 223/653 (34%), Positives = 369/653 (56%), Gaps = 68/653 (10%) Query: 193 NFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYK 252 ++R+ + F F+ NN ++ YI+++NE+ +L ++ ++L++ Sbjct: 3 DYRDVFIEFLTTFKG---------NNNQNK---YIERINELVAYRKKSLIIEFSDVLSF- 49 Query: 253 QTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSCK 312 E+L ++++N + ++ I++ + D ++ L D D++++ VR + Sbjct: 50 -NENLAYEIINNTKIILPILEGALYDHILQL--DPTYQRDIEKVH-----VRIVGIPRVI 101 Query: 313 GMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRG-----VIQE 367 +R++ DI KLI + G++++ TPV + A +K D E V++ Sbjct: 102 ELRKIRSTDIGKLITIDGILVKVTPVKERIYKATYKHIHPDCMQEFEWPEDEEMPEVLEM 161 Query: 368 PARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSC 427 P C + C +P LI + D Q +QE P+ VP GQ P + + + D+LVDS Sbjct: 162 PTICPK--CGKPGQFRLIPEKTKLIDWQKAVIQERPEEVPSGQLPRQLEIILEDDLVDSA 219 Query: 428 RAGDRIEVTGTF---RSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQE 484 R GDR++VTG + P++ SR +++ Y+ V ++ VS K LD E Sbjct: 220 RPGDRVKVTGILDIKQDSPVKRGSR-----AVFDIYMKVSSIE-VSQKVLD--------E 265 Query: 485 LMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQL 544 ++ I+++D KI+++A + + SIAPSIY ++K+ + L L Sbjct: 266 VI--------------ISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWELKEALALAL 311 Query: 545 FGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAY 604 FGG K R RGDI+IL+ GDP T+KSQ+LQ++ ++ PR VYT+GKGS+A GLTA Sbjct: 312 FGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGSTAAGLTAA 370 Query: 605 ITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITT 664 + R+ T + LE+GALVL+DGG+ IDE DKM D R +HE MEQQT+SIAKAGI+ Sbjct: 371 VVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSIAKAGIVAK 430 Query: 665 LNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHL 724 LNAR++++A+ NP RY PV++NI+LPP +LSRFDL++++ D+ E+ DRELA ++ Sbjct: 431 LNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQ-DRELANYI 489 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 +++ S +++ ++ L YI+YA++++ P IT AK + +V MRK S Sbjct: 490 LDVH-----SGKSTKNIIDIDTLRKYIAYARKYVTPKITSEAKNLITDFFVEMRK--KSS 542 Query: 785 RSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYA 837 + + I T RQLE++IR++EA+AKM LK V ED + A+ ++R ++ Sbjct: 543 ETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIMRLFLESVG 595 >5BK4-5 nrPDB Length = 775 Score = 687 bits (1772), Expect = 0.0, Method: Composition-based stats. Identities = 228/765 (29%), Positives = 381/765 (49%), Gaps = 111/765 (14%) Query: 189 ECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNL 248 E +F+NF++ F+ D + Y QL + +L ++ +L Sbjct: 26 EIIKSFKNFILEFRL-----------------DSQFIYRDQLRNNILVKNYSLTVNMEHL 68 Query: 249 LAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIV---------------DNNLDYD- 292 + Y ED+Y +L + P ++I + + I + + + ++D D Sbjct: 69 IGY--NEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDS 126 Query: 293 --LDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCN 350 L+ + T F + N +R+L+ + K++ L G+++ ++ + C Sbjct: 127 LLLNSLPT-FQLILNSNANQIP-LRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCR 184 Query: 351 VCDHTMAVEIDR------GVIQEPARC------ERIDCNE-------------PNSMSLI 385 C HT ++ I+ + P C E NE P+ +I Sbjct: 185 NCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIII 244 Query: 386 HNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIR 445 H F D+Q +KLQE P+ VP G+ P ++++ L + G R+ + G + SI Sbjct: 245 HESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY-SIYNS 303 Query: 446 ANSRQRVLK---------SLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVE 496 N ++ Y+ ++ ++ DV+TS+I Sbjct: 304 KNGAGSGRSGGGNGGSGVAIRTPYIKILGIQS------DVETSSIWN------------- 344 Query: 497 EVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGG 556 V T+++ + +++ LY +L SIAPSI+ ED+KK I+ L GG+ K G Sbjct: 345 SVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGM 404 Query: 557 RYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVL 616 R RGDIN+LL GDP T+KSQ+L++V K++P VYTSGKGSSA GLTA + RD T++ L Sbjct: 405 RLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYL 464 Query: 617 ESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASAN 676 E GA+VL+DGGV CIDEFDKM D R +HE MEQQTISIAKAGI T LN+R+S+LA+AN Sbjct: 465 EGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAAN 524 Query: 677 PIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHI 736 PI RY+ +NID +LSRFD++++V D +E+ D +A H+ N++ + Sbjct: 525 PIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQ 584 Query: 737 SQDD----VLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRK---MGDDSRSDEK 789 +Q + + +E + YI+Y + P ++ A +L +V +RK + + ++ Sbjct: 585 NQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERS 644 Query: 790 RITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNL 849 I T RQLE++IR+ E+ AK++L + + V EA+RL +++ D A+ G ++ Sbjct: 645 SIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQ-- 702 Query: 850 VQTGKSVIQ-RKLQEDLSREI-------MNVLKDQASDSMSFNEL 886 +G S+ + R+ +++L R + L+ + D+ F++L Sbjct: 703 -ASGTSLSEIRRFEQELKRRLPIGWSTSYQTLRREFVDTHRFSQL 746 >3JC7-2 nrPDB Length = 868 Score = 659 bits (1700), Expect = 0.0, Method: Composition-based stats. Identities = 212/679 (31%), Positives = 340/679 (50%), Gaps = 83/679 (12%) Query: 206 RKILDEREEFINNTTDE--ELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLN 263 R I E + F+ TDE Y ++ + E+ + +L ++ R+L K L+ L Sbjct: 205 RTIARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALF--LAK 262 Query: 264 YPQEVISIMDQTIKDCMVSLIVDNNLDY-DLDEIETKFYKVRPYNVGSCKGMRELNPNDI 322 P+E++ I D + L Y D I ++ + VR + + +REL +++ Sbjct: 263 CPEEMLKIFDLVAMEA-------TELHYPDYARIHSEIH-VRISDFPTIYSLRELRESNL 314 Query: 323 DKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERI----DCNE 378 L+ + G+V R T V P +K F C C + Q+ RI +C Sbjct: 315 SSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILG-----PFFQDSNEEIRISFCTNCKS 369 Query: 379 PNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGT 438 + + + + Q + LQE P VP G+ P + + +LVD + G+ +EVTG Sbjct: 370 KGPFRVNGEKTVYRNYQRVTLQEAPGTVPPGRLPRHREVILLADLVDVSKPGEEVEVTGI 429 Query: 439 FRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEEV 498 +++ + K+ + + ++ + KR + +T+ +E + +V Sbjct: 430 YKNNYDGNLNA----KNGFPVFATIIEANSI--KRREGNTANEGEEGL----------DV 473 Query: 499 RQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRY 558 T+++ + R+++ + + S+APSIY D+K + LFGG K Sbjct: 474 FSWTEEEEREFRKISRDRGIIDKIISSMAPSIYGHRDIKTAVACSLFGGVPKNVNGKHSI 533 Query: 559 RGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLES 618 RGDIN+LL GDP T+KSQIL+YV K R V+ +G+G+SAVGLTA + +D TK+ LE Sbjct: 534 RGDINVLLLGDPGTAKSQILKYVEKTAHRAVFATGQGASAVGLTASVRKDPITKEWTLEG 593 Query: 619 GALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPI 678 GALVL+D GVC IDEFDKM+D R+ +HE MEQQ+ISI+KAGI+TTL AR SI+A+ANP Sbjct: 594 GALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQSISISKAGIVTTLQARCSIIAAANPN 653 Query: 679 GSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEH--- 735 G RYN LP+ +N+ L P+LSRFD++ +V D VDE+ D LA + + ++ PE+ Sbjct: 654 GGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLVDEEADERLATFVVDSHVRSHPENDED 713 Query: 736 ---------------ISQDDV-----------------------LPVEFLTMYISYAKEH 757 +D++ +P E L YI YA+ Sbjct: 714 REGEELKNNGESAIEQGEDEINEQLNARQRRLQRQRKKEEEISPIPQELLMKYIHYARTK 773 Query: 758 IHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVV 817 I+P + + ++ R Y +R+ + S T R LES++R+AE+ AKM+L V Sbjct: 774 IYPKLHQMDMDKVSRVYADLRRESISTGS----FPITVRHLESILRIAESFAKMRLSEFV 829 Query: 818 ELEDVQEAVRLIRSAIKDY 836 D+ A++++ + D Sbjct: 830 SSYDLDRAIKVVVDSFVDA 848 >5U8S-7 nrPDB Length = 845 Score = 577 bits (1487), Expect = e-165, Method: Composition-based stats. Identities = 231/676 (34%), Positives = 366/676 (54%), Gaps = 47/676 (6%) Query: 201 FKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQ 260 F F + +D D + + + R L + D N + ++E+L Sbjct: 113 FTELFCRAIDNNMPLPTKEIDYKDDVLDVILNQRRLRNERMLSDRTNEI---RSENLMDT 169 Query: 261 LLNYPQEVISIMDQTIKDCMVSLIVDNNLDYDLDEIETKFYKVRPYNVGSC----KGMRE 316 ++ P + + + ++D + Y L R Y + +R+ Sbjct: 170 TMDPPSSMNDALREVVEDETELFPPNLTRRYFLYFKPLSQNCARRYRKKAISSKPLSVRQ 229 Query: 317 LNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCNVCDHTMAVEIDRGVIQEPARCERIDC 376 + + + +LI ++G++ R + V P ++V + C+ C + + E++ + C +C Sbjct: 230 IKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEVFQEVNSRTFTPLSECTSEEC 289 Query: 377 --NEPNSMSLIHNR-CSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRI 433 N+ + R F+ Q K+QE VP G P S+++ V LV S GD + Sbjct: 290 SQNQTKGQLFMSTRASKFSAFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIV 349 Query: 434 EVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVD-TSTIEQELMQNKVDH 492 +VTG F P + L +TY++ V++ K TS +E+ +M Sbjct: 350 DVTGIFLPAPYTGFKALKA-GLLTETYLEAQFVRQHKKKFASFSLTSDVEERVM------ 402 Query: 493 NEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTF 552 E+ D+Y+ LA+SIAP IY DVKK +LL L GG +K Sbjct: 403 ------------------ELITSGDVYNRLAKSIAPEIYGNLDVKKALLLLLVGGVDKRV 444 Query: 553 TKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTK 612 G + RGDIN+ L GDP +KSQ+L+ + KI+PRGVYT+GKGSS VGLTA + +D T Sbjct: 445 GDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSSGVGLTAAVMKDPVTD 504 Query: 613 QLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSIL 672 +++LE GALVL+D G+CCIDEFDKM +S R+ +HEVMEQQTISI+KAGI TTLNAR+SIL Sbjct: 505 EMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISISKAGINTTLNARTSIL 564 Query: 673 ASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDK 732 A+ANP+ RYNP L +NI+LP LLSRFD+++L+LD +D +LA+H+T +++ +K Sbjct: 565 AAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDDEKLAEHVTYVHMHNK 624 Query: 733 PEHISQDDVLPVEF--LTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKR 790 + D PVE + YI+YAK P+++EA +V+AY+ +R+ D R + + Sbjct: 625 QPDL---DFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQAYIRLRQ--DSKREMDSK 678 Query: 791 IT---ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDM 847 + AT R L +IRL++A AK++L ++V+++DV+EA+RL+R + + + K D Sbjct: 679 FSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLVRVSKESLYQETNKSKEDE 738 Query: 848 NLVQTGKSVIQRKLQE 863 + ++I++ LQE Sbjct: 739 SPTTKIFTIIKKMLQE 754 >5XF8-3 nrPDB Length = 997 Score = 541 bits (1394), Expect = e-154, Method: Composition-based stats. Identities = 219/752 (29%), Positives = 356/752 (47%), Gaps = 111/752 (14%) Query: 241 LNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIVDNNLDYD-LDEIETK 299 + + +L + + + +L P I ++ + D S+ + + + Sbjct: 122 IIISLDDLREFDR--SFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPW 179 Query: 300 FYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDM------KVAFFKCNVCD 353 + R L ++KL++++G+V +++ V P + + + D Sbjct: 180 KLSFKGSFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKLIRSVHYAAKTGRFHYRD 239 Query: 354 HTMAVEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPH 413 +T A I PA D E N ++ + +F D Q I +QE P+ P GQ P Sbjct: 240 YTDATTTLTTRIPTPAIYPTEDT-EGNKLTTEYGYSTFIDHQRITVQEMPEMAPAGQLPR 298 Query: 414 SISLCVYDELVDSCRAGDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKR 473 SI + + D+LVD + GDR+ V G F+S+ ++ S+ Sbjct: 299 SIDVILDDDLVDKTKPGDRVNVVGVFKSLGAGGMNQSN------------------SNTL 340 Query: 474 LDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYEL 533 + T + + V + +TD D+ I +++ ++D++ +L++S+APSIY Sbjct: 341 IGFKTLILGNTVYPLHARSTGVAARQMLTDFDIRNINKLSKKKDIFDILSQSLAPSIYGH 400 Query: 534 EDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSG 593 + +KK ILL L GG K G RGDINIL+ GDPST+KSQ+L++V + T+G Sbjct: 401 DHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDPSTAKSQLLRFVLNTASLAIATTG 460 Query: 594 KGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQT 653 +GSS VGLTA +T D +T + LE+GA+VL+D GV CIDEFDKM+D R +HEVMEQQT Sbjct: 461 RGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVCIDEFDKMTDVDRVAIHEVMEQQT 520 Query: 654 ISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVD 713 ++IAKAGI TTLNAR S++A+ANP+ +Y+ N +NI LP LLSRFDL+++V D ++ Sbjct: 521 VTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQNIALPDSLLSRFDLLFVVTDDIN 580 Query: 714 EKNDRELAKHLTNLY-------LEDKPEH--------ISQD-DVLPVEF----------- 746 E DR +++H+ + LE +P + +D D+ P E Sbjct: 581 EIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLAVGEDADINPEEHSNSGAGVENEG 640 Query: 747 -----------------------------------------LTMYISYAKEHIHPIITEA 765 L Y+ YAKE + P +T+ Sbjct: 641 EDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLVTIPFLRKYVQYAKERVIPQLTQE 700 Query: 766 AKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEA 825 A +V+ Y +R + +S T R LE++IRLA AHAK++L V D + A Sbjct: 701 AINVIVKNYTDLRNDDNTKKS-----PITARTLETLIRLATAHAKVRLSKTVNKVDAKVA 755 Query: 826 VRLIRSAI--KDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASDSMSF 883 L+R A+ +D D ID + +++ +R Q+ + ++ AS+S S Sbjct: 756 ANLLRFALLGEDIGND-----IDEEESEYEEALSKRSPQKSPKKR--QRVRQPASNSGSP 808 Query: 884 NELIKQINEHSQDRVESSDIQEALSRLQQEDK 915 + + + S S + L R Q +++ Sbjct: 809 IKSTPRRSTASSVNATPSSARRIL-RFQDDEQ 839 >4R7Z-A nrPDB Length = 338 Score = 425 bits (1092), Expect = e-119, Method: Composition-based stats. Identities = 146/341 (42%), Positives = 212/341 (62%), Gaps = 6/341 (1%) Query: 502 TDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGD 561 + ++ I+E+A R+D+ + SIAP+IY ++VKKGI L LFGG ++ G R RGD Sbjct: 1 SPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGD 60 Query: 562 INILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGAL 621 I++LL GDP +KSQIL+YV + PR +YTS Sbjct: 61 IHVLLVGDPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 120 Query: 622 VLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681 GG IDE DKMSD RSV+HE +EQQTISI+KAGI TLNAR++++A+ANP R Sbjct: 121 XXXXGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGR 180 Query: 682 YNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDV 741 +N E IDLPP LLSRFDL+++++D+ D+K D E+A+H+ + + E ++ Sbjct: 181 FNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVR-RGESEVVAPK-- 237 Query: 742 LPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEK---RITATTRQL 798 +P E L YI+YA+++IHP+I+E A E+ + YV MRK ++ +E+ I T RQL Sbjct: 238 IPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITARQL 297 Query: 799 ESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATD 839 E++IRL+EAHA+M+L +V ED +EA++L+ +K A D Sbjct: 298 EALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAMD 338 >3F8T-A nrPDB Length = 506 Score = 312 bits (800), Expect = 4e-85, Method: Composition-based stats. Identities = 130/443 (29%), Positives = 205/443 (46%), Gaps = 55/443 (12%) Query: 424 VDSCRA--GDRIEVTGTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTI 481 V+ R G I + G R + +R+ ++ T ++V V+ + I Sbjct: 108 VERIRPMDGALISIEGVVREV----RGAERLEHAIVDTGSELVAVRLHGHRLGPGLRVEI 163 Query: 482 EQELMQNKVDHNEVEEVRQITD-----QDLAKIREVAAREDLYSLLARSIAPSIYELEDV 536 + +D EV + I + +L + RE+A +D + AR+IAP + E+V Sbjct: 164 LGIVRSATLDALEVHKKDPIPEVHPDPAELEEFRELA-DKDPLTTFARAIAP-LPGAEEV 221 Query: 537 KKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYV-HKITPRGVYTSGKG 595 K + LQLF K + +++LL G P S+IL +V + PRGVY + Sbjct: 222 GKMLALQLFSCVGKNSER-------LHVLLAGYPVVC-SEILHHVLDHLAPRGVYVDLRR 273 Query: 596 SSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTIS 655 + LTA + D + L +GA VL+DGG+ +D + + R L E M++ T++ Sbjct: 274 TELTDLTAVLKED---RGWALRAGAAVLADGGILAVDHLEGAPEPHRWALMEAMDKGTVT 330 Query: 656 IAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEK 715 + GI LNAR ++LA+ NP G ++ P+ P IDL LS FDL+ + VD + Sbjct: 331 VD--GI--ALNARCAVLAAINP-GEQW-PSDPPIARIDLDQDFLSHFDLIAFL--GVDPR 382 Query: 716 NDRELAKHLTNLYLEDKPEHISQDDVLP-VEFLTMYISYA-KEHIHPIITEAAKTELVRA 773 +PE QD +P L Y+ YA +EH P +TE A+ L Sbjct: 383 P--------------GEPE--EQDTEVPSYTLLRRYLLYAIREHPAPELTEEARKRLEHW 426 Query: 774 YVGMRKMGDDSRSDEKR-ITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSA 832 Y R+ ++ + T RQLES+ RLA+AHA+M+L + VE EDV A L+ Sbjct: 427 YETRREEVEERLGMGLPTLPVTRRQLESVERLAKAHARMRLSDDVEPEDVDIAAELVDWY 486 Query: 833 IKDYATDPKTGKIDMNLVQTGKS 855 ++ A G D + + K Sbjct: 487 LET-AMQIPGG--DEIRISSLKP 506 >2R44-A nrPDB Length = 331 Score = 41.0 bits (94), Expect = 0.003, Method: Composition-based stats. Identities = 54/317 (17%), Positives = 122/317 (38%), Gaps = 48/317 (15%) Query: 563 NILLCGDPSTSKSQILQYVHKIT----PRGVYTSGKGSSAVGLTAYITRDVDTKQLVLES 618 +ILL G P +K+ + + K R +T S L + + ++ Sbjct: 48 HILLEGVPGLAKTLSVNTLAKTMDLDFHRIQFTPDLLPS--DLIGTMIYNQHKGNFEVKK 105 Query: 619 GALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPI 678 G + DE ++ +S L E M+++ ++I L+ +LA+ NP+ Sbjct: 106 GPVF---SNFILADEVNRSPAKVQSALLECMQEKQVTIGDT--TYPLDNPFLVLATQNPV 160 Query: 679 --GSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHI 736 Y LP + RF ++ + L +D++++ E+ + ++N+ + + I Sbjct: 161 EQEGTYP----------LPEAQVDRF-MMKIHLTYLDKESELEVMRRVSNMNFNYQVQKI 209 Query: 737 SQDDVLPVEFLTMYISYAKEHIHPIITEAAKTE--LVRAYVGMRKMGDDSRSDEKRIT-- 792 + + + I+ + + + + + ++ I Sbjct: 210 VSKNDV---------LEIRNEINKVTISESLEKYIIELVFATRFPAEYGLEAEASYILYG 260 Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQT 852 A+TR ++ R+A+A A ++ V ED++E A D +I +N Sbjct: 261 ASTRAAINLNRVAKAMAFFNNRDYVLPEDIKE-----------VAYDILNHRIILNYEAE 309 Query: 853 GKSVIQRKLQEDLSREI 869 + + R++ E + R++ Sbjct: 310 AEGISTRQIIETILRKV 326 >5EXS-A nrPDB Length = 260 Score = 39.4 bits (90), Expect = 0.008, Method: Composition-based stats. Identities = 33/198 (16%), Positives = 68/198 (34%), Gaps = 24/198 (12%) Query: 561 DINILLCGDPSTSKSQILQYVHKITPR-----------GVYTSGKGSSAVGLTAYITRDV 609 D ++L+ G+ T K + + +H + R + S G + Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 610 DTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARS 669 T + +G L++GG +DE M + L V++++T + G T N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 670 SILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYL 729 I+A+ + + + E+ L R + V+ + + ++A L L Sbjct: 147 RIIAATHKNLEK------MIEDGTFREDLYYRLN-VFPIEMAPLRERVEDIALLLNELIS 199 Query: 730 EDKPEHISQDDVLPVEFL 747 + E + Sbjct: 200 RMEHEKRGSIRFNSAAIM 217 >4QHS-A nrPDB Length = 267 Score = 39.0 bits (89), Expect = 0.010, Method: Composition-based stats. Identities = 42/203 (20%), Positives = 80/203 (39%), Gaps = 26/203 (12%) Query: 535 DVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPR--GVYTS 592 D K LL L KT D N+++ G + K + +Y+H +PR G + + Sbjct: 21 DTKSLKLLALADKVAKT---------DANVMILGPSGSGKEVMSRYIHNASPRKEGPFIA 71 Query: 593 GKGSSAVG--LTAYI---TRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHE 647 ++ L A + + T + G + GG +DE +M + ++ L Sbjct: 72 INCAAIPDNMLEATLFGYEKGAFTGAVQACPGKFEQAQGGTILLDEISEMDLNLQAKLLR 131 Query: 648 VMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYL 707 V++++ + + L+ R +LA++N +Y + L R ++ L Sbjct: 132 VLQEREVERLGSRKSIKLDVR--VLATSNRDLKQY------VQAGHFREDLYYRLNVFPL 183 Query: 708 VLDKVDEKND--RELAKHLTNLY 728 + E+ D LA HL + Sbjct: 184 TWPALCERKDDIEPLANHLIERH 206 >5EXX-A nrPDB Length = 343 Score = 38.3 bits (87), Expect = 0.016, Method: Composition-based stats. Identities = 25/132 (18%), Positives = 50/132 (37%), Gaps = 17/132 (12%) Query: 561 DINILLCGDPSTSKSQILQYVHKITPR-----------GVYTSGKGSSAVGLTAYITRDV 609 D ++L+ G+ T K + + +H + R + S G + Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 610 DTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARS 669 T + +G L++GG +DE M + L V++++T + G T N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 670 SILASANPIGSR 681 I+A+ + + Sbjct: 147 RIIAATHKNLEK 158 >3DZD-A nrPDB Length = 368 Score = 37.5 bits (85), Expect = 0.030, Method: Composition-based stats. Identities = 37/215 (17%), Positives = 75/215 (34%), Gaps = 35/215 (16%) Query: 564 ILLCGDPSTSKSQILQYVHKITPR-GVYTSGKGSSAVGLTAYIT-----RDVDTKQLVLE 617 +L+ G+ T K + + +H+ + R G + +S A + T L + Sbjct: 155 VLITGESGTGKEIVARLIHRYSGRKGAFVDLNCASIPQELAESELFGHEKGAFTGALTRK 214 Query: 618 SGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANP 677 G L L+D G +DE ++ ++ L V+E T S + G + ++++ N Sbjct: 215 KGKLELADQGTLFLDEVGELDQRVQAKLLRVLE--TGSFTRLGGNQKIEVDIRVISATNK 272 Query: 678 IGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHIS 737 + + L R + + +L L K + Sbjct: 273 NLEE------EIKKGNFREDLYYRLSVFQI---------------YLPPLRERGKDVIL- 310 Query: 738 QDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVR 772 L FL + K++ ++E K L++ Sbjct: 311 ----LAEYFLKKFAKEYKKNCF-ELSEETKEYLMK 340 >1OFI-A nrPDB Length = 310 Score = 37.1 bits (84), Expect = 0.035, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 46/126 (36%), Gaps = 16/126 (12%) Query: 522 LARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDI-------NILLCGDPSTSK 574 + + I D K+ + + L + + + + + NIL+ G K Sbjct: 9 IVSELDQHIIGQADAKRAVAIAL-----RNRWRRMQLQEPLRHEVTPKNILMIGPTGVGK 63 Query: 575 SQILQYVHKITPRGVYTSGKGSSAVGLTAYITR-DVDTKQLVLESGALVLS--DGGVCCI 631 ++I + + K+ + + + + D + L +G + + G+ I Sbjct: 64 TEIARRLAKLA-NAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAGGAIDAVEQNGIVFI 122 Query: 632 DEFDKM 637 DE DK+ Sbjct: 123 DEIDKI 128 >1NY5-A nrPDB Length = 387 Score = 36.7 bits (83), Expect = 0.042, Method: Composition-based stats. Identities = 42/232 (18%), Positives = 79/232 (34%), Gaps = 27/232 (11%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLV-LESGALV 622 +L+ G+ K + + +HK++ R K A I RD+ +L E GA Sbjct: 163 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 217 Query: 623 -----------LSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSI 671 L+DGG +DE ++S ++ L V+E + G + I Sbjct: 218 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 275 Query: 672 LASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKND--RELAKHLTNLYL 729 LA+ N + + L R ++ + + + E+ + LA H + Sbjct: 276 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 329 Query: 730 EDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMG 781 + + E L Y Y + E A ++ ++ Sbjct: 330 RKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELS 381 >4LZZ-A nrPDB Length = 268 Score = 36.7 bits (83), Expect = 0.049, Method: Composition-based stats. Identities = 42/232 (18%), Positives = 79/232 (34%), Gaps = 27/232 (11%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLV-LESGALV 622 +L+ G+ K + + +HK++ R K A I RD+ +L E GA Sbjct: 44 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 98 Query: 623 -----------LSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSI 671 L+DGG +DE ++S ++ L V+E + G + I Sbjct: 99 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 156 Query: 672 LASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKND--RELAKHLTNLYL 729 LA+ N + + L R ++ + + + E+ + LA H + Sbjct: 157 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 210 Query: 730 EDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMG 781 + + E L Y Y + E A ++ ++ Sbjct: 211 RKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELS 262 >3M6A-A nrPDB Length = 543 Score = 36.3 bits (82), Expect = 0.060, Method: Composition-based stats. Identities = 68/348 (19%), Positives = 124/348 (35%), Gaps = 52/348 (14%) Query: 531 YELEDVKKGILLQLFGGTNKTFTKGGRYRGDINILLCGDPSTSKSQILQYVHKITPRGVY 590 + LE VK+ IL L K +G I + L G P K+ + + + K Sbjct: 84 HGLEKVKERILEYL--AVQKLTK---SLKGPI-LCLAGPPGVGKTSLAKSIAK------- 130 Query: 591 TSGKGSSAVGLTAYITRDVDTKQLVLESGALV------LSDGG----VCCIDEFDKMSDS 640 + G+ + L GA+ + G V +DE DKMS Sbjct: 131 SLGRKFVRISLGGVRDESEIRGHRRTYVGAMPGRIIQGMKKAGKLNPVFLLDEIDKMSSD 190 Query: 641 TR----SVLHEVME-QQTISIAKAGIITTLN-ARSSILASANPIGSRYNPNLPVTENIDL 694 R S + EV++ +Q S + I T + ++ +A+AN + + P E I++ Sbjct: 191 FRGDPSSAMLEVLDPEQNSSFSDHYIEETFDLSKVLFIATANNLATIPGPLRDRMEIINI 250 Query: 695 PPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKP----EHISQDDVLPVEFLTMY 750 + + + +V D + K +E +NL L D+ + Sbjct: 251 AG--YTEIEKLEIVKDHLLPKQIKEHGLKKSNLQLRDQAILDIIRYYTREAGVRSLERQL 308 Query: 751 ISYAKEHIHPIITEAAK-----TELVRAYVGMR--KMGDDSRSDEKRI-------TATTR 796 + ++ I+ E K + ++ ++G R + G D+ + T Sbjct: 309 AAICRKAAKAIVAEERKRITVTEKNLQDFIGKRIFRYGQAETEDQVGVVTGLAYTTVGGD 368 Query: 797 QLESMIRLAEAHAKMKLK---NVVELEDVQEAVRLIRSAIKDYATDPK 841 L + L+ K+ L V E Q A +RS ++ +P Sbjct: 369 TLSIEVSLSPGKGKLILTGKLGDVMRESAQAAFSYVRSKTEELGIEPD 416 >1IN6-A nrPDB Length = 334 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 55/152 (36%), Gaps = 30/152 (19%) Query: 512 VAAREDLYSLLARSIAP----SIYELEDVKKGILLQLFGGTNKTFTKGGRYRGDI--NIL 565 + +Y + + P E+VKK + L L + + RG++ ++L Sbjct: 5 LTPERTVYDSGVQFLRPKSLDEFIGQENVKKKLSLAL---------EAAKMRGEVLDHVL 55 Query: 566 LCGDPSTSKSQILQYVHKITPRGVY-TSGKGSSAVGLTAYITRDVDTKQLVLESGALVLS 624 L G P ++ + + ++ TSG G A I L Sbjct: 56 LAGPPGLGRTTLAHIIASELQTNIHVTSGPVLVKQGDMAAILTS--------------LE 101 Query: 625 DGGVCCIDEFDKMSDSTRSVLHEVMEQQTISI 656 G V IDE +++ + +L+ +E I I Sbjct: 102 RGDVLFIDEIHRLNKAVEELLYSAIEDFQIDI 133 >4L4U-A nrPDB Length = 447 Score = 35.6 bits (80), Expect = 0.11, Method: Composition-based stats. Identities = 42/232 (18%), Positives = 78/232 (33%), Gaps = 27/232 (11%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLV-LESGALV 622 +L+ G+ K + + +HK + R K A I RD+ +L E GA Sbjct: 171 VLITGESGVGKEVVARLIHKSSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 225 Query: 623 -----------LSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSI 671 L+DGG +DE ++S ++ L V+E + G + I Sbjct: 226 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 283 Query: 672 LASANPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKND--RELAKHLTNLYL 729 LA+ N + + L R ++ + + + E+ + LA H + Sbjct: 284 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 337 Query: 730 EDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMG 781 + + E L Y Y + E A ++ ++ Sbjct: 338 RKYAKEVEGFTKSAQELLLSYPWYGNVRELKNVIERAVLFSEGKFIDRGELS 389 >4F19-A nrPDB Length = 381 Score = 35.2 bits (79), Expect = 0.14, Method: Composition-based stats. Identities = 18/61 (29%), Positives = 33/61 (54%), Gaps = 5/61 (8%) Query: 28 PQLSSPALFYSSSSSQGDIYGRN---NSQNLSQGEGNIRAAIGSSPLNFPSSSQRQNSDV 84 P ++P L +++ G+N N+Q +S N+ AAIG+ P+ P+++ R N D Sbjct: 210 PDFAAPTLAGLDDATKVARVGKNVATNTQGVSPAAANVSAAIGAVPV--PAAADRSNPDA 267 Query: 85 F 85 + Sbjct: 268 W 268 >3K1J-A nrPDB Length = 604 Score = 35.2 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 50/260 (19%), Positives = 87/260 (33%), Gaps = 41/260 (15%) Query: 587 RGVYTSGKGSSAVGLTAYITRDVDTKQ-------LVLESGALVLSDGGVCCIDEFDKMSD 639 + + G+ A L + D +E G + + GV IDE +S Sbjct: 156 KAPFIDATGAHAGALLGDVRHDPFQSGGLGTPAHERVEPGMIHRAHKGVLFIDEIATLSL 215 Query: 640 STRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLL 699 + L M+++ K I S + P+ + L N+D Sbjct: 216 KMQQSLLTAMQEK-----KFPITGQSEMSSGAMVRTEPVPCDFV--LVAAGNLD------ 262 Query: 700 SRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISY--AKEH 757 +DK+ + + +Y+ D + L +++ ++ Sbjct: 263 --------TVDKMHPALRSRIRGYGYEVYMRT----TMPDTIENRRKLVQFVAQEVKRDG 310 Query: 758 IHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVV 817 P T+ A E+VR + +T R L ++R A A K K V Sbjct: 311 KIPHFTKEAVEEIVR-------EAQKRAGRKGHLTLRLRDLGGIVRAAGDIAVKKGKKYV 363 Query: 818 ELEDVQEAVRLIRSAIKDYA 837 E EDV EAV++ + K A Sbjct: 364 EREDVIEAVKMAKPLEKQLA 383 Score = 29.8 bits (65), Expect = 5.6, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 16/24 (66%) Query: 563 NILLCGDPSTSKSQILQYVHKITP 586 ++LL G+P T KS + Q + ++ P Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >4ZPX-A nrPDB Length = 413 Score = 35.2 bits (79), Expect = 0.15, Method: Composition-based stats. Identities = 48/253 (18%), Positives = 85/253 (33%), Gaps = 41/253 (16%) Query: 587 RGVYTSGKGSSAVGLTAYITRDVDTKQ-------LVLESGALVLSDGGVCCIDEFDKMSD 639 + + G+ A L + D +E G + + GV IDE +S Sbjct: 193 KAPFIDATGAHAGALLGDVRHDPFQSGGLGTPAHERVEPGMIHRAHKGVLFIDEIATLSL 252 Query: 640 STRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSRYNPNLPVTENIDLPPPLL 699 + L M+++ K I S + P+ + L N+D Sbjct: 253 KMQQSLLTAMQEK-----KFPITGQSEMSSGAMVRTEPVPCDFV--LVAAGNLD------ 299 Query: 700 SRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISY--AKEH 757 +DK+ + + +Y+ D + L +++ ++ Sbjct: 300 --------TVDKMHPALRSRIRGYGYEVYMRT----TMPDTIENRRKLVQFVAQEVKRDG 347 Query: 758 IHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVV 817 P T+ A E+VR + +T R L ++R A A K K V Sbjct: 348 KIPHFTKEAVEEIVR-------EAQKRAGRKGHLTLRLRDLGGIVRAAGDIAVKKGKKYV 400 Query: 818 ELEDVQEAVRLIR 830 E EDV EAV++ + Sbjct: 401 EREDVIEAVKMAK 413 Score = 30.6 bits (67), Expect = 3.7, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 16/24 (66%) Query: 563 NILLCGDPSTSKSQILQYVHKITP 586 ++LL G+P T KS + Q + ++ P Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >2R65-A nrPDB Length = 268 Score = 34.8 bits (78), Expect = 0.17, Method: Composition-based stats. Identities = 53/243 (21%), Positives = 90/243 (37%), Gaps = 34/243 (13%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGS---SAVGLTAYITRDVDTKQLVLESGA 620 +LL G P T K+ + + V ++ G S VGL A RD+ ++ + Sbjct: 47 VLLVGPPGTGKTLLAKAVAGEAHVPFFSMGGSSFIEMFVGLGASRVRDLFETAKK-QAPS 105 Query: 621 LVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTIS--IAKAGIITTLNARSSILASANPI 678 ++ D ID K + V +QT++ +A+ + NA +LA+ N Sbjct: 106 IIFIDE----IDAIGKSRAAGGVVSGNDEREQTLNQLLAEMDGFGSENAPVIVLAATN-- 159 Query: 679 GSRYNPNLPVTENIDLPPPLL--SRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHI 736 P L P L+ RFD LV +K D + ++++ Sbjct: 160 -------RPEI----LDPALMRPGRFDRQVLV-----DKPDFNGRVEILKVHIKG---VK 200 Query: 737 SQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTR 796 +DV E + A + II EAA +R+ + E+ I + Sbjct: 201 LANDVNLQEVAKLTAGLAGADLANIINEAALLAGRNNQKEVRQQHLK-EAVERGIAGLEK 259 Query: 797 QLE 799 +LE Sbjct: 260 KLE 262 >4YPL-A nrPDB Length = 555 Score = 34.4 bits (77), Expect = 0.24, Method: Composition-based stats. Identities = 47/238 (19%), Positives = 87/238 (36%), Gaps = 32/238 (13%) Query: 531 YELEDVKKGILLQLFGGTNKTFTKGGRYRGDINIL-LCGDPSTSKSQILQYVHKITPRGV 589 Y L+DVK+ IL L + T+G R IL L G P K+ + + + + R Sbjct: 82 YGLKDVKERILEYL---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 138 Query: 590 YTSGKGSSAVGLTAYITRDVDT-----KQLVLESGALVLSDGGVCCIDEFDKMSDSTR-- 642 + G V A I T ++ + V V +D+ DKMS R Sbjct: 139 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDQIDKMSSDWRGD 196 Query: 643 --SVLHEVME-QQTISIAKAGIITTLN-ARSSILASANPIGSRYNPNLPVTENIDLPPPL 698 S + EV++ +Q + + + ++ + +AN + +P PL Sbjct: 197 PASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQ-------------TIPRPL 243 Query: 699 LSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVLPVEFLTMYISYAKE 756 L R +++ + + +A+ + + +V L + Y +E Sbjct: 244 LDRMEVIEI--PGYTNMEKQAIARQYLWPKQVRESGMEGRIEVTDAAILRVISEYTRE 299 >1QVR-A nrPDB Length = 854 Score = 34.4 bits (77), Expect = 0.27, Method: Composition-based stats. Identities = 77/413 (18%), Positives = 145/413 (35%), Gaps = 81/413 (19%) Query: 542 LQLFGGTNKTFTKGGRYRGDINILL---------CGDPSTSKSQILQYVHKITPRGVYTS 592 L G + + R I ILL G+P K+ I V + R V Sbjct: 163 LAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAI---VEGLAQRIV--- 216 Query: 593 GKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVME-Q 651 KG GL + + L+ G+L+ G EF+ + ++V+ EV++ Q Sbjct: 217 -KGDVPEGL-------KGKRIVSLQMGSLL---AGAKYRGEFE---ERLKAVIQEVVQSQ 262 Query: 652 QTISIAKAGIITTLNARSS--ILASAN---PIGSRYN------PNLPVTENIDLPPPLLS 700 + + + T + A + + + N P +R L I+ P L Sbjct: 263 GEVILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPALER 322 Query: 701 RFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVL-PVEFLTMYISYAKEHIH 759 RF VY+ D+ + + + L Y IS ++ YI+ + Sbjct: 323 RFQPVYV--DEPTVEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERR---- 376 Query: 760 PIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVEL 819 + + A + A +R + + + + QLE + LK + Sbjct: 377 --LPDKAIDLIDEAAARLRMALESAPEEIDALERKKLQLE--------IEREALKKEKDP 426 Query: 820 EDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQASD 879 D QE ++ A + + K+ + + + + + REI+ L++ Sbjct: 427 -DSQERLK---------AIEAEIAKLTEE-------IAKLRAEWEREREILRKLREA--- 466 Query: 880 SMSFNELIKQINEHSQDRVESSDIQEALSRLQQ-EDKVIVLGEGVR--RSVRL 929 +E+ ++I + + + L + E +V L E +R R VRL Sbjct: 467 QHRLDEVRREIELAERQYDLNRAAELRYGELPKLEAEVEALSEKLRGARFVRL 519 >2IY3-A nrPDB Length = 432 Score = 34.0 bits (76), Expect = 0.33, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 43/94 (45%), Gaps = 12/94 (12%) Query: 796 RQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKS 855 +QL + RL EA +++ + + ED++ +R IR A+ D + + + Sbjct: 3 QQLSA--RLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVAR----------D 50 Query: 856 VIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQ 889 ++R +E L ++++ L + E +K+ Sbjct: 51 FVERVREEALGKQVLESLTPAEVILATVYEALKE 84 >1RJ9-B nrPDB Length = 300 Score = 33.6 bits (75), Expect = 0.43, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 43/94 (45%), Gaps = 12/94 (12%) Query: 796 RQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKS 855 +QL + RL EA +++ + + ED++ +R IR A+ D + + + Sbjct: 3 QQLSA--RLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVTR----------D 50 Query: 856 VIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQ 889 ++R +E L ++++ L + E +K+ Sbjct: 51 FVERVREEALGKQVLESLTPAEVILATVYEALKE 84 >4YPN-A nrPDB Length = 293 Score = 33.2 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 35/130 (26%), Positives = 52/130 (40%), Gaps = 15/130 (11%) Query: 531 YELEDVKKGILLQLFGGTNKTFTKGGRYRGDINIL-LCGDPSTSKSQILQYVHKITPRGV 589 Y L+DVK+ IL L + T+G R IL L G P K+ + + + + R Sbjct: 115 YGLKDVKERILEYL---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 171 Query: 590 YTSGKGSSAVGLTAYITRDVDT-----KQLVLESGALVLSDGGVCCIDEFDKMSDSTR-- 642 + G V A I T ++ + V V +DE DKMS R Sbjct: 172 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGD 229 Query: 643 --SVLHEVME 650 S + EV++ Sbjct: 230 PASAMLEVLD 239 >1OJL-A nrPDB Length = 304 Score = 33.2 bits (74), Expect = 0.49, Method: Composition-based stats. Identities = 43/255 (16%), Positives = 86/255 (33%), Gaps = 38/255 (14%) Query: 561 DINILLCGDPSTSKSQILQYVHKITPR-----------GVYTSGKGSSAVGLTAYITRDV 609 D +L+ GD T K + + +H + R + S S G + Sbjct: 25 DATVLIHGDSGTGKELVARALHACSARSDRPLVTLNCAALNESLLESELFGH----EKGA 80 Query: 610 DTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARS 669 T G V +DGG +DE +S + L ++++ + + G T++ Sbjct: 81 FTGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQEREVQ--RVGSNQTISVDV 138 Query: 670 SILASANPIGSRYNPNLPVTENID---LPPPLLSRFDLVYLVLDKVDEKNDR--ELAKHL 724 ++A+ + + E + L R ++V + + + ++ + LA H Sbjct: 139 RLIAATH---------RDLAEEVSAGRFRQDLYYRLNVVAIEMPSLRQRREDIPLLADHF 189 Query: 725 TNLYLEDKPEHISQDDVLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDS 784 + E + + ++ L Y P + + RA V + Sbjct: 190 LRRFAERNRKVVKGFTPQAMDLLIHY-------DWPGNIRELENAIERAVVLLTGEYISE 242 Query: 785 RSDEKRITATTRQLE 799 R I AT + E Sbjct: 243 RELPLAIAATPIKTE 257 >4BS1-B nrPDB Length = 173 Score = 33.2 bits (74), Expect = 0.53, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 50/125 (40%), Gaps = 19/125 (15%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLV-LESGALV 622 +L+ G+ K + + +HK++ R K A I RD+ +L E GA Sbjct: 27 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 81 Query: 623 -----------LSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSI 671 L+DGG +DE ++S ++ L V+E + G + I Sbjct: 82 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 139 Query: 672 LASAN 676 LA+ N Sbjct: 140 LAATN 144 >2FFH-A nrPDB Length = 425 Score = 33.2 bits (74), Expect = 0.59, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 43/94 (45%), Gaps = 12/94 (12%) Query: 796 RQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKS 855 +QL + RL EA +++ + + ED++ +R IR A+ D + + + Sbjct: 3 QQLSA--RLQEAIGRLRGRGRITEEDLKATLREIRRALMDADVNLEVTR----------D 50 Query: 856 VIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQ 889 ++R +E L ++++ L + E +K+ Sbjct: 51 FVERVREEALGKQVLESLTPAEVILATVYEALKE 84 >4PEK-A nrPDB Length = 258 Score = 32.9 bits (73), Expect = 0.65, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 52/114 (45%), Gaps = 5/114 (4%) Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMN---- 848 T R+LES++ A ++ L + + D+ A+R+ I A D +TG+I+ Sbjct: 137 LTERELESLLEYARSYGMEPLIIINDENDLDIALRIGARFIGIAARDWETGEINKENQRK 196 Query: 849 LVQTGKSVIQRKLQEDLS-REIMNVLKDQASDSMSFNELIKQINEHSQDRVESS 901 L+ S + + +E +S R + L+ ++ + + E ++ +E S Sbjct: 197 LISMIPSNVVKVAKEGISERNEIEELRKLGVNAFLIGSSLMRNPEKIKELIEGS 250 >6ED3-A nrPDB Length = 848 Score = 32.9 bits (73), Expect = 0.74, Method: Composition-based stats. Identities = 66/527 (12%), Positives = 182/527 (34%), Gaps = 85/527 (16%) Query: 448 SRQRVLKSLYKTYVDVVHVKKVS--DKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQD 505 ++L + +V V +V+ + + + +++ V ++ Sbjct: 128 GHGASPQALREAFVKVRGSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRDNEI 187 Query: 506 LAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGG-TNKTFTKGGRYRGDINI 564 ++ ++ R +L P + + +G+ ++ G ++ D+ Sbjct: 188 RRVVQVLSRRTKNNPVLIGE--PGV-GKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGS 244 Query: 565 LLCG--DPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALV 622 ++ G + ++ + I G+ + + I T + +++G ++ Sbjct: 245 MVAGSKYRGEFEERLKAVLDDIKNSA----GQIITFIDELHTIVGAGATGEGAMDAGNMI 300 Query: 623 ---LSDG-----GVCCIDEFDKMSDST--------RSVLHEVMEQQTISI-----AKAGI 661 L+ G G +DE+ K + + + E + TI I + + Sbjct: 301 KPMLARGELRLVGATTLDEYRKHIEKDAALERRFQQVYVGEPSVEDTIGILRGLKDRYEV 360 Query: 662 ITTLNARSSILASANPIGSRYNPNL-PVTENIDLPPPLLSRFDLVYLVLDKVDEKNDR-- 718 + S L +A + RY + IDL SR + ++D + Sbjct: 361 HHGVRITDSALVAAATLSDRYITARFLPDKAIDLVDEAASR------LRMEIDSRPVEID 414 Query: 719 ELAKHLTNLYLEDKPEHISQDDVLPVEF--LTMYISYAKEHIHPIITEAAKTELVRAYVG 776 E+ + + L +E+ +D+ L ++ KE + + T + V Sbjct: 415 EVERLVRRLEIEEMALSKEEDEASAERLAKLRSELADQKEKLAELTTRWQNEKNAIEIVR 474 Query: 777 -MRKMGDDSRSDEKR-----------------ITATTRQLESMIRLAEAHAKMKLKNVVE 818 +++ + R + +R I ++L++ + A+A ++ LK V Sbjct: 475 DLKEQLEALRGESERAERDGDLAKAAELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVG 534 Query: 819 LEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVLKDQAS 878 +D+ + + T G++ G++ +++++L + ++ + Sbjct: 535 PDDI--------ADVVSAWTGIPAGRL-----LEGETAKLLRMEDELGKRVIGQKAAVTA 581 Query: 879 DSMSFNELIKQINEHSQ----------DRVESSDIQEALSRLQQEDK 915 S + +++ ++ V +++ +AL+ +D+ Sbjct: 582 VSDAVRRSRAGVSDPNRPTGAFMFLGPTGVGKTELAKALADFLFDDE 628 >4I5O-A nrPDB Length = 363 Score = 32.9 bits (73), Expect = 0.76, Method: Composition-based stats. Identities = 27/172 (15%), Positives = 57/172 (33%), Gaps = 23/172 (13%) Query: 530 IYELEDVKKGILLQLFGGTNKTFTKGGR---YRGDINILLCGDPSTSKSQILQYVHKI-- 584 + E KK + + ++ + G NILL G + K+ + + + ++ Sbjct: 17 VIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLD 76 Query: 585 ----TPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKM-SD 639 + G + I + + ++ + G+ IDE DK+ Sbjct: 77 VPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQK-----AQRGIVYIDEIDKISRK 131 Query: 640 STRSVLHEVMEQQTISIAKAGI-ITTLNARSSILASANPIGSRYNPNLPVTE 690 S + T ++ G+ L +A+ P G R +P + Sbjct: 132 SDNPSI-------TRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQEFLQ 176 >4PA8-A nrPDB Length = 258 Score = 32.5 bits (72), Expect = 0.83, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 53/114 (46%), Gaps = 5/114 (4%) Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMN---- 848 T R+LES++ A ++ L + + D+ A+R+ I ++ + +TG+I+ Sbjct: 137 LTERELESLLEYARSYGMEPLILINDENDLDIALRIGARFIVIFSMNFETGEINKENQRK 196 Query: 849 LVQTGKSVIQRKLQEDLS-REIMNVLKDQASDSMSFNELIKQINEHSQDRVESS 901 L+ S + + D+S R + L+ ++ + + + E ++ +E S Sbjct: 197 LISMIPSNVVKVAHLDISERNEIEELRKLGVNAFLISSSLMRNPEKIKELIEGS 250 >1HQC-A nrPDB Length = 324 Score = 32.5 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 50/144 (34%), Gaps = 22/144 (15%) Query: 563 NILLCGDPSTSKSQILQYVHK-ITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGAL 621 ++LL G P K+ + + + TSG G A I A Sbjct: 40 HLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAIL-------------AN 86 Query: 622 VLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANPIGSR 681 L +G + IDE ++S L+ ME + I I AR+ L P + Sbjct: 87 SLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIV---IGQGPAARTIRLEL--PRFTL 141 Query: 682 YNPNLPVTENIDLPPPLLSRFDLV 705 + PLLSRF +V Sbjct: 142 IGATTRPGL---ITAPLLSRFGIV 162 >1F5N-A nrPDB Length = 592 Score = 32.5 bits (72), Expect = 0.84, Method: Composition-based stats. Identities = 23/174 (13%), Positives = 70/174 (40%), Gaps = 9/174 (5%) Query: 743 PVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMI 802 P+E Y+K + + + + + Y RK + + + ++++ Sbjct: 417 PLEEEVKAGIYSKPGGYRLFVQKLQDLKKKYYEEPRKGIQAEEILQTYLKSKESMTDAIL 476 Query: 803 RLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQ 862 + + + + + VE + A +++ K + + M + ++L Sbjct: 477 QTDQTLTEKEKEIEVERVKAESA----QASAKMLHEMQRKNEQMMEQKERSYQEHLKQLT 532 Query: 863 EDLSREIMNVLKDQ----ASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQ 912 E + + + +LK+Q A +L+K+ + + R+ ++IQ+ +++++ Sbjct: 533 EKMENDRVQLLKEQERTLALKLQEQEQLLKEGFQ-KESRIMKNEIQDLQTKMRR 585 >4ZXZ-A nrPDB Length = 447 Score = 32.1 bits (71), Expect = 1.2, Method: Composition-based stats. Identities = 36/208 (17%), Positives = 69/208 (33%), Gaps = 26/208 (12%) Query: 634 FDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASA----------------NP 677 + M + + M + I A+ GI T + R S +A+ +P Sbjct: 119 LNSMPEEGQVKSCLTMGEGAIIAARTGITTITDFRISDIAAGRQGAPLHAFFDALLLHHP 178 Query: 678 IGSRYNPNLPVTENIDL-PPPLLSRF-DLVYLVLDKVDEKNDRELAKHLTNLYLE-DKPE 734 R N+ N+ PP + R D Y + +H TN E DK Sbjct: 179 TKLRACQNIGGIANVTFIPPDVDGRLTDEYYDFDTGPGTVMIDAVVRHFTNGEQEYDKDG 238 Query: 735 HISQDDVLPVEFLTMYISYAKEHIHPIIT---EAAKTELVRAYVGMRKMGDDSRSDEKRI 791 + + + E + ++ + + P T E + L + R D+ Sbjct: 239 EMGKRGKVDQELVDDFLKHPYFQLDPPKTCGREVFRDSLAHDLIR-RAEAKGLSPDDIVA 297 Query: 792 TATTRQLESMIRLAEAHAKMKLKNVVEL 819 T T +S++ +A+ + ++ Sbjct: 298 TVTRITAQSIV---DAYRRYAPSQEIDE 322 >2ISS-A nrPDB Length = 313 Score = 32.1 bits (71), Expect = 1.3, Method: Composition-based stats. Identities = 22/81 (27%), Positives = 35/81 (43%), Gaps = 6/81 (7%) Query: 790 RITATTRQL-ESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMN 848 R L E++ R+AE A ++ K +V EAV+ +R ++ K D Sbjct: 145 PFVCGARDLGEALRRIAEGAAMIRTKGEAGTGNVVEAVKHMRRVMEQIKQVTKM--EDEE 202 Query: 849 LVQTGKSVIQRKLQEDLSREI 869 LV GK + +L RE+ Sbjct: 203 LVAYGKEIG---APVELLREV 220 >4LT9-A nrPDB Length = 269 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 57/130 (43%), Gaps = 6/130 (4%) Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQT 852 T R+LES++ A ++ L + + D+ A+R+ I ++ D K+ + Sbjct: 137 LTERELESLLEYARSYGMEPLILINDENDLDIALRIGARFISIFSVD--KSKLSSTGGYS 194 Query: 853 GKSVIQRKLQEDLSREIMNVLKDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQ 912 I ++ Q L I + + A+ + +E +I E + V + I +L ++ Sbjct: 195 SSYSINKENQRKLISMIPSNVVKVAA-TFKVSER-NEIEELRKLGVNAFLISSSL--MRN 250 Query: 913 EDKVIVLGEG 922 +K+ L EG Sbjct: 251 PEKIKELIEG 260 >3IFE-A nrPDB Length = 434 Score = 30.9 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 35/94 (37%) Query: 763 TEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIRLAEAHAKMKLKNVVELEDV 822 + A K EL+ + K+ S D + T Q+E L E ++ L V ++ Sbjct: 22 SNAMKEELIERFTRYVKIDTQSNEDSHTVPTTPGQIEFGKLLVEELKEVGLTEVTMDDNG 81 Query: 823 QEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSV 856 L + KD +D TGK+V Sbjct: 82 YVMATLPANTDKDVPVIGFLAHLDTATDFTGKNV 115 >5AOU-A nrPDB Length = 258 Score = 30.9 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 33/65 (50%) Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQT 852 T R+LES++ A + L + + D+ A+R+ I Y+ + +TG+I+ + Sbjct: 137 LTERELESLLEYARGYGMEPLILINDENDLDIALRIGARFITIYSMNFETGEINKENQRK 196 Query: 853 GKSVI 857 S+I Sbjct: 197 LISMI 201 >1UM8-A nrPDB Length = 376 Score = 30.9 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 29/135 (21%), Positives = 50/135 (37%), Gaps = 18/135 (13%) Query: 563 NILLCGDPSTSKSQILQYVHKITPRGVYTSGKGS-SAVGLTAYITRDVDTKQLVLESGAL 621 NILL G + K+ + Q + K + S S + G ++ T+ L + Sbjct: 74 NILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNV 133 Query: 622 VLSDGGVCCIDEFDKM------SDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASA 675 + G+ IDE DK+ TR V E ++Q + I + ++ Sbjct: 134 QKAQKGIVFIDEIDKISRLSENRSITRDVSGEGVQQALLKIVEGSLVN-----------I 182 Query: 676 NPIGSRYNPNLPVTE 690 P G R +P + Sbjct: 183 PPKGGRKHPEGNFIQ 197 >2Q8F-A nrPDB Length = 407 Score = 30.9 bits (68), Expect = 2.8, Method: Composition-based stats. Identities = 18/84 (21%), Positives = 33/84 (39%), Gaps = 4/84 (4%) Query: 223 ELYYIKQLNEMRELGTSNLNLDARNLLAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVS 282 + +YI+ L E+ + + A + A D ++ N +VI M Q + + S Sbjct: 82 QSWYIQSLQELLDFKDKS----AEDAKAIYDFTDTVIRIRNRHNDVIPTMAQGVIEYKES 137 Query: 283 LIVDNNLDYDLDEIETKFYKVRPY 306 VD ++ +FY R Sbjct: 138 FGVDPVTSQNVQYFLDRFYMSRIS 161 >4HSE-A nrPDB Length = 397 Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 59/319 (18%), Positives = 107/319 (33%), Gaps = 63/319 (19%) Query: 542 LQLFGGTNKTFTKGGRYRGDINILL---------CGDPSTSKSQILQYVHKITPRGVYTS 592 L G + + R I ILL G+P K+ I V + R V Sbjct: 26 LAAEGKLDPVIGRDEEIRRVIQILLRRTKNNPVLIGEPGVGKTAI---VEGLAQRIV--- 79 Query: 593 GKGSSAVGLTAYITRDVDTKQLVLESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVME-Q 651 KG GL + + L+ G+L+ G EF+ + ++V+ EV++ Q Sbjct: 80 -KGDVPEGL-------KGKRIVSLQMGSLL---AGAKYRGEFE---ERLKAVIQEVVQSQ 125 Query: 652 QTISIAKAGIITTLNARSS--ILASAN---PIGSRYN------PNLPVTENIDLPPPLLS 700 + + + T + A + + + N P +R L I+ P L Sbjct: 126 GEVILFIDELHTVVGAGKAEGAVDAGNMLKPALARGELRLIGATTLDEYREIEKDPALER 185 Query: 701 RFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHISQDDVL-PVEFLTMYI-------- 751 RF VY+ D+ + + + L Y IS ++ YI Sbjct: 186 RFQPVYV--DEPTVEETISILRGLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDK 243 Query: 752 -------SYAKEHIHPIITEAAKTELVRAYVGM---RKMGDDSRSDEKRITATTRQLESM 801 + A+ + L R + + R+ + + + + E + Sbjct: 244 AIDLIDEAAARLRMALESAPEEIDALERKKLQLEIEREALKKEKDPDSQERLKAIEAE-I 302 Query: 802 IRLAEAHAKMKLKNVVELE 820 +L E AK++ + E E Sbjct: 303 AKLTEEIAKLRAEWERERE 321 >3U5Z-B nrPDB Length = 324 Score = 30.9 bits (68), Expect = 2.9, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 35/122 (28%), Gaps = 15/122 (12%) Query: 564 ILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLESGALVL 623 IL P T K+ + + + V + R T S A Sbjct: 51 ILHSPSPGTGKTTVAKALCH----DVNADMMFVNGSDCKIDFVRGPLTN---FASAASFD 103 Query: 624 SDGGVCCIDEFDKM----SDSTRSVLHEVMEQQTISIAKA----GIITTLNARSSILASA 675 V IDEFD+ S E I A GII L +R ++ Sbjct: 104 GRQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQSRCRVITFG 163 Query: 676 NP 677 P Sbjct: 164 QP 165 >1RWG-A nrPDB Length = 757 Score = 30.6 bits (67), Expect = 3.7, Method: Composition-based stats. Identities = 33/148 (22%), Positives = 57/148 (38%), Gaps = 18/148 (12%) Query: 558 YRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLE 617 GD+ + L D ST+ ++ + + R ++ +GS+ LT T V Sbjct: 506 VSGDVTVCLGADISTASGAKVETI--VDHRNLH---QGSNT--LTTAAGTIAGTAGTV-- 556 Query: 618 SGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGII--TTLNARSSILASA 675 VL DG ++ F + S LH + E ++ S + I T+ R+ Sbjct: 557 ---EVLGDGRWVHLEGFGGYAMLDDSPLHVLRETRSGSWSGVNINGSATVQQRNFATLYV 613 Query: 676 N----PIGSRYNPNLPVTENIDLPPPLL 699 N P+ Y + ++DL LL Sbjct: 614 NHGVGPVAGSYAYMVAPGASVDLTRKLL 641 >2GGM-A nrPDB Length = 172 Score = 30.2 bits (66), Expect = 4.8, Method: Composition-based stats. Identities = 25/159 (15%), Positives = 59/159 (37%), Gaps = 9/159 (5%) Query: 755 KEHIHPIITEAAKTELVRAYVGMRKMGDDSRSDEKRITATTRQLESMIR-LAEAHAKMKL 813 + P +TE K E+ A+ D + T ++L+ +R L K ++ Sbjct: 18 RMSPKPELTEEQKQEIREAF--------DLFDADGTGTIDVKELKVAMRALGFEPKKEEI 69 Query: 814 KNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQTGKSVIQRKLQEDLSREIMNVL 873 K ++ D + ++ T + K + + +S + + + Sbjct: 70 KKMISEIDKEGTGKMNFGDFLTVMTQKMSEKDTKEEILKAFKLFDDDETGKISFKNLKRV 129 Query: 874 KDQASDSMSFNELIKQINEHSQDRVESSDIQEALSRLQQ 912 + ++++ EL + I+E +D QE L +++ Sbjct: 130 AKELGENLTDEELQEMIDEADRDGDGEVSEQEFLRIMKK 168 >4IJB-A nrPDB Length = 256 Score = 29.8 bits (65), Expect = 5.1, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 33/65 (50%) Query: 793 ATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLVQT 852 T R+LES++ A ++ L + + D+ A+R+ I ++ D +T +I+ + Sbjct: 137 LTERELESLLEYARSYGMEPLIEINDENDLDIALRIGARFIGIWSQDNETLEINKENQRK 196 Query: 853 GKSVI 857 S+I Sbjct: 197 LISMI 201 >4WV3-A nrPDB Length = 529 Score = 29.8 bits (65), Expect = 5.9, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 26/72 (36%), Gaps = 8/72 (11%) Query: 358 VEIDRGVIQEPARCERIDCNEPNSMSLIHNRCSFADKQVIKLQETPDFVPDGQTPHSISL 417 VE++ +IQ PA E P+ LI + K P+ +P I+ Sbjct: 427 VEVESTLIQHPAVQECAVIGCPDQSRLIKPKAFIILK--------PEQIPSEALIRQITD 478 Query: 418 CVYDELVDSCRA 429 +++ R Sbjct: 479 HCTEKMAAYKRP 490 >4OWW-B nrPDB Length = 211 Score = 29.4 bits (64), Expect = 7.6, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 39/102 (38%), Gaps = 4/102 (3%) Query: 414 SISLCVYDELVDSCRAGDRIEVT----GTFRSIPIRANSRQRVLKSLYKTYVDVVHVKKV 469 SI++ V+D++ + + GD I +T F+ R L+ + + + V Sbjct: 49 SINISVWDDVGNLIQPGDIIRLTKGYASVFKGCLTLYTGRGGDLQKIGEFCMVYSEVPNF 108 Query: 470 SDKRLDVDTSTIEQELMQNKVDHNEVEEVRQITDQDLAKIRE 511 S+ + T + +QN + + + + A + Sbjct: 109 SEPNPEYSTQQAPNKAVQNDSNPSASQPTTGPSAASPASENQ 150 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.122 0.302 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 29,806,027 Number of Sequences: 36641 Number of extensions: 1139919 Number of successful extensions: 3405 Number of sequences better than 10.0: 60 Number of HSP's better than 10.0 without gapping: 33 Number of HSP's successfully gapped in prelim test: 71 Number of HSP's that attempted gapping in prelim test: 3073 Number of HSP's gapped (non-prelim): 192 length of query: 933 length of database: 10,336,785 effective HSP length: 106 effective length of query: 827 effective length of database: 6,452,839 effective search space: 5336497853 effective search space used: 5336497853 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 63 (29.0 bits)