BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P30656 (287 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3NZW-K nrPDB 600 e-172 5CZ8-K nrPDB 459 e-130 5L64-K nrPDB 367 e-102 5L5A-K nrPDB 347 3e-96 6EPF-5 nrPDB 286 1e-77 5LN3-5 nrPDB 284 3e-77 3UNB-K nrPDB 277 4e-75 3UNF-K nrPDB 264 3e-71 6AVO-C nrPDB 257 5e-69 5FMG-L nrPDB 203 8e-53 6HEC-1 nrPDB 113 1e-25 3H4P-a nrPDB 103 6e-23 5GJQ-a nrPDB 99 3e-21 3IPM-H nrPDB 97 1e-20 6EPC-1 nrPDB 97 1e-20 5LEZ-N nrPDB 95 3e-20 6AVO-A nrPDB 93 1e-19 5FGI-H nrPDB 82 3e-16 6AVO-B nrPDB 81 4e-16 3UNH-H nrPDB 78 4e-15 5MPC-h nrPDB 78 5e-15 6HV7-H nrPDB 78 5e-15 3UNF-N nrPDB 77 6e-15 6EPF-2 nrPDB 77 7e-15 6HUB-H nrPDB 77 1e-14 5L4G-8 nrPDB 77 1e-14 5FMG-I nrPDB 75 3e-14 1Q5R-H nrPDB 59 2e-09 5FMG-E nrPDB 59 3e-09 5FGE-J nrPDB 57 7e-09 3WXR-K nrPDB 57 9e-09 2Z5C-C nrPDB 57 1e-08 1Q5Q-H nrPDB 56 2e-08 5FMG-N nrPDB 56 2e-08 1G0U-D nrPDB 56 2e-08 6HE5-A nrPDB 55 4e-08 3H4P-A nrPDB 54 5e-08 5GJR-F nrPDB 53 2e-07 3UNE-I nrPDB 52 2e-07 4Y8P-I nrPDB 51 6e-07 5GJQ-g nrPDB 50 1e-06 5VFT-S nrPDB 48 4e-06 5L4G-U nrPDB 48 4e-06 6EPF-6 nrPDB 47 1e-05 5FMG-M nrPDB 47 1e-05 6EPE-7 nrPDB 46 2e-05 5LF6-M nrPDB 46 2e-05 2JAY-A nrPDB 45 3e-05 6J30-C nrPDB 44 8e-05 5FMG-B nrPDB 44 9e-05 5FMG-H nrPDB 42 2e-04 4FZC-A nrPDB 42 3e-04 5LEZ-C nrPDB 41 6e-04 2KU2-A nrPDB 40 0.001 5LF3-J nrPDB 39 0.002 5LZP-A nrPDB 37 0.009 4YA5-C nrPDB 37 0.014 5JI2-A nrPDB 36 0.015 3NZW-E nrPDB 34 0.063 3NZW-L nrPDB 34 0.086 5FMG-C nrPDB 34 0.090 5FMG-F nrPDB 33 0.16 6GOP-M nrPDB 32 0.21 5FMG-K nrPDB 31 0.51 5XM3-A nrPDB 31 0.78 1H4I-A nrPDB 30 0.82 1Q1R-A nrPDB 30 0.96 2D0V-A nrPDB 30 1.0 1OFH-G nrPDB 30 1.2 4R7Y-A nrPDB 30 1.2 5EXI-A nrPDB 30 1.5 5LE5-B nrPDB 29 2.5 5NYF-A nrPDB 28 3.8 5HJ5-A nrPDB 28 3.9 1FUI-A nrPDB 28 4.0 1LRW-A nrPDB 28 4.4 3EG4-A nrPDB 27 6.8 >3NZW-K nrPDB Length = 287 Score = 600 bits (1547), Expect = e-172, Method: Compositional matrix adjust. Identities = 287/287 (100%), Positives = 287/287 (100%) Query: 1 MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHT 60 MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHT Sbjct: 1 MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHT 60 Query: 61 DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTM 120 DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTM Sbjct: 61 DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTM 120 Query: 121 AGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYT 180 AGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYT Sbjct: 121 AGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYT 180 Query: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA Sbjct: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 Query: 241 HRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 HRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 241 HRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 >5CZ8-K nrPDB Length = 221 Score = 459 bits (1180), Expect = e-130, Method: Compositional matrix adjust. Identities = 220/221 (99%), Positives = 220/221 (99%) Query: 67 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAAD 126 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVK VIEINPFLLGTMAGGAAD Sbjct: 1 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAAD 60 Query: 127 CQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 186 CQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT Sbjct: 61 CQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 120 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS 246 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS Sbjct: 121 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS 180 Query: 247 GGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 GGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 181 GGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 221 >5L64-K nrPDB Length = 211 Score = 367 bits (941), Expect = e-102, Method: Compositional matrix adjust. Identities = 175/212 (82%), Positives = 191/212 (90%), Gaps = 1/212 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+F+ G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC FWE L Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ K GP +YYVDS+G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGN 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 R+ G F VGSG +AYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV Sbjct: 120 RISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 179 Query: 256 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 180 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 211 >5L5A-K nrPDB Length = 211 Score = 347 bits (891), Expect = 3e-96, Method: Compositional matrix adjust. Identities = 164/212 (77%), Positives = 189/212 (89%), Gaps = 1/212 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+FQ G+I AVDSRA+AG+++++ V KVIEINP+LLGTM+G AADCQ+WET L Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +CRL+ LR ERISV+AASK+LSN++ QY+G GLSMG+MICG+ +K GP +YYVD GT Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK-GPGLYYVDEHGT 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 RL G++F GSG T+AYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV Sbjct: 120 RLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 179 Query: 256 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 180 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 211 >6EPF-5 nrPDB Length = 263 Score = 286 bits (731), Expect = 1e-77, Method: Compositional matrix adjust. Identities = 136/203 (66%), Positives = 165/203 (81%), Gaps = 1/203 (0%) Query: 69 KIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQ 128 +I++ HGTTTLAF+FQ G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC Sbjct: 53 RIEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCS 112 Query: 129 FWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIY 188 FWE L QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ K GP +Y Sbjct: 113 FWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLY 171 Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 YVDS+G R+ G F VGSG +A+GV+D Y +DL VE+A L +R+I A +RDAYSGG Sbjct: 172 YVDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGG 231 Query: 249 SVNLYHVTEDGWIYHGNHDVGEL 271 +VNLYHV EDGWI + +V +L Sbjct: 232 AVNLYHVREDGWIRVSSDNVADL 254 >5LN3-5 nrPDB Length = 263 Score = 284 bits (726), Expect = 3e-77, Method: Compositional matrix adjust. Identities = 137/205 (66%), Positives = 164/205 (80%), Gaps = 1/205 (0%) Query: 70 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQF 129 I++ HGTTTLAF+F+ G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC F Sbjct: 54 IEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSF 113 Query: 130 WETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYY 189 WE L QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ K GP +YY Sbjct: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYY 172 Query: 190 VDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGS 249 VDS+G R+ G F VGSG +AYGV+D Y +DL VE A L +R+I A +RDAYSGG+ Sbjct: 173 VDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGA 232 Query: 250 VNLYHVTEDGWIYHGNHDVGELFWK 274 VNLYHV EDGWI + +V +L K Sbjct: 233 VNLYHVREDGWIRVSSDNVADLHEK 257 >3UNB-K nrPDB Length = 205 Score = 277 bits (708), Expect = 4e-75, Method: Compositional matrix adjust. Identities = 133/196 (67%), Positives = 158/196 (80%), Gaps = 1/196 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+F G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC FWE L Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ K GP +YYVDS+G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWD-KRGPGLYYVDSEGN 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 R+ G F VGSG +AYGV+D Y +DL VE+A L +R+I A +RDAYSGG+VNLYHV Sbjct: 120 RISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHV 179 Query: 256 TEDGWIYHGNHDVGEL 271 EDGWI + +V +L Sbjct: 180 REDGWIRVSSDNVADL 195 >3UNF-K nrPDB Length = 204 Score = 264 bits (675), Expect = 3e-71, Method: Compositional matrix adjust. Identities = 125/202 (61%), Positives = 160/202 (79%), Gaps = 1/202 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+FQ G+IVAVDSRATAG++++S + KVIEINP+LLGTM+G AADCQ+WE L Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +CRL+ LR ERISV+AASK+LSN++ QY+G GLSMG+MICG+ +K GP +YYVD +GT Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKK-GPGLYYVDDNGT 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 RL G +F GSG T+AYGV+DS Y+ DLS E+A LG+R+I A HRD YSGG VN+YH+ Sbjct: 120 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYHM 179 Query: 256 TEDGWIYHGNHDVGELFWKVKE 277 EDGW+ + DV +L +K E Sbjct: 180 KEDGWVKVESSDVSDLLYKYGE 201 >6AVO-C nrPDB Length = 204 Score = 257 bits (656), Expect = 5e-69, Method: Compositional matrix adjust. Identities = 121/202 (59%), Positives = 160/202 (79%), Gaps = 1/202 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+FQ G+I AVDSRA+AG+++++ V KVIEINP+LLGTM+G AADCQ+WE L Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +CRL+ LR ERISV+AASK+LSN++ QY+G GLSMG+MICG+ +K GP +YYVD GT Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK-GPGLYYVDEHGT 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 RL G++F GSG T+AYGV+DS Y+ +LS E+A LG+R+I A HRD+YSGG VN+YH+ Sbjct: 120 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHM 179 Query: 256 TEDGWIYHGNHDVGELFWKVKE 277 EDGW+ + DV +L + +E Sbjct: 180 KEDGWVKVESTDVSDLLHQYRE 201 >5FMG-L nrPDB Length = 211 Score = 203 bits (516), Expect = 8e-53, Method: Compositional matrix adjust. Identities = 95/185 (51%), Positives = 138/185 (74%), Gaps = 1/185 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+F+ GIIVAVDSRA+ G++++SQ V+K+IEIN +LGTMAGGAADC +WE +LG Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +++ELR E+ISV AAS ILSN++YQYKG GL G ++ GY G ++YVD G Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDHT-GFNMFYVDDSGK 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 +++G++F GSG T+AY +LDS Y ++L+++ A+ L + +I A RD SGG V ++H+ Sbjct: 120 KVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFHI 179 Query: 256 TEDGW 260 ++G+ Sbjct: 180 HKNGY 184 >6HEC-1 nrPDB Length = 202 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 63/203 (31%), Positives = 113/203 (55%), Gaps = 2/203 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTT+ + G+++A + RAT GN++AS+ KK+ +I + T AG D QF + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 + L+E+R + + +V A + + SNL+ Y+ + +I G EG +IY +D G Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGID-SEGKSIYSIDPIGG 119 Query: 196 RL-KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + + DI GSG AYGVL+ + ++ V++A+ L R+I +A RD+ SG +++ Sbjct: 120 AIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVK 179 Query: 255 VTEDGWIYHGNHDVGELFWKVKE 277 +TED + + +V ++ K ++ Sbjct: 180 ITEDEFYQYSPEEVEQILAKFRK 202 >3H4P-a nrPDB Length = 219 Score = 103 bits (258), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 59/198 (29%), Positives = 105/198 (53%), Gaps = 1/198 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTT+ +I+A D RA+ GN VA + KK+ +I+ ++ T+AG D Q L Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 ++ +L+++R I A + +LSN+++ + +I GY EG ++ +D G Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 121 Query: 196 RLKGDIF-CVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + F GSG AYGVL++ Y D+SVE+ + L ++ +A RD +SG ++L Sbjct: 122 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 181 Query: 255 VTEDGWIYHGNHDVGELF 272 +T+DG + ++ ++ Sbjct: 182 ITKDGVKIFEDEEIEKIL 199 >5GJQ-a nrPDB Length = 239 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 54/189 (28%), Positives = 96/189 (50%), Gaps = 1/189 (0%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 +++ GTT +A +F GG+++ DSR T G+++A++ K+ I+ + +G AAD Q Sbjct: 30 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYV 190 + Q H + E V A+ + + Y+Y+ L G +I G+ +EG +Y V Sbjct: 90 ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSV 148 Query: 191 DSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 250 G ++ GSG ++ YG +D+ Y+ ++ E+ L ++ A RD SGG + Sbjct: 149 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVI 208 Query: 251 NLYHVTEDG 259 L + E G Sbjct: 209 RLAAIAESG 217 >3IPM-H nrPDB Length = 217 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 53/188 (28%), Positives = 103/188 (54%), Gaps = 3/188 (1%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134 GTTT+ + +I+A + R T N++ + KK+ +I+ + T+AG D Q ++ Sbjct: 8 GTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLVRYM 67 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194 ++ L+ L+ + + + A + +LSN++ Q K + ++ G P ++ +D+ G Sbjct: 68 KAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYMVQLLVGGI--DTAPHVFSIDAAG 125 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 ++ GSG F YGVL+S Y ++V++ + L R+I AA RD+ SGG +++ Sbjct: 126 GSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMIDVAV 185 Query: 255 VT-EDGWI 261 +T +DG++ Sbjct: 186 ITRKDGYV 193 >6EPC-1 nrPDB Length = 238 Score = 96.7 bits (239), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 52/189 (27%), Positives = 96/189 (50%), Gaps = 1/189 (0%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 +++ GTT +A +F GG+++ DSR T G+++A++ K+ I+ + +G AAD Q Sbjct: 29 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDHIFCCRSGSAADTQAV 88 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYV 190 + Q H + E V A+ + + Y+Y+ L G +I G+ +EG +Y V Sbjct: 89 ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSV 147 Query: 191 DSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 250 G ++ GSG ++ YG +D+ Y+ ++ ++ L ++ A RD SGG + Sbjct: 148 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDECLQFTANALALAMERDGSSGGVI 207 Query: 251 NLYHVTEDG 259 L + + G Sbjct: 208 RLAAIQQSG 216 >5LEZ-N nrPDB Length = 205 Score = 95.1 bits (235), Expect = 3e-20, Method: Compositional matrix adjust. Identities = 53/184 (28%), Positives = 92/184 (50%), Gaps = 1/184 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A +F GG+++ DSR T G+++A++ K+ I+ + +G AAD Q + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 Q H + E V A+ + + Y+Y+ L G +I G+ +EG +Y V G Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSVPMGGM 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 ++ GSG ++ YG +D+ Y+ ++ E+ L ++ A RD SGG + L + Sbjct: 120 MVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAI 179 Query: 256 TEDG 259 E G Sbjct: 180 AESG 183 >6AVO-A nrPDB Length = 199 Score = 92.8 bits (229), Expect = 1e-19, Method: Compositional matrix adjust. Identities = 60/185 (32%), Positives = 95/185 (51%), Gaps = 4/185 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A F GG+++ DSR +AG V ++ K+ ++ + ++G AAD Q Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 Q LH + +E V AA+ ++ N+ Y+Y+ LS M+ G+ ++EG +Y + G Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVY--GTLGG 117 Query: 196 RLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 L F + GSG TF YG +D+ YK +S E+ +I A RD SGG + L Sbjct: 118 MLTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVT 177 Query: 255 VTEDG 259 +T G Sbjct: 178 ITAAG 182 >5FGI-H nrPDB Length = 244 Score = 82.0 bits (201), Expect = 3e-16, Method: Compositional matrix adjust. Identities = 53/179 (29%), Positives = 91/179 (50%), Gaps = 4/179 (2%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134 G T + +F G+++A D+R+T G VA + K+ I+P + AG AAD + + Sbjct: 12 GATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQLI 71 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGT-MICGYTRKEGPTIYYVDSD 193 GS LH L V +A ++L +++Y+G +G +I G ++ + + Sbjct: 72 GSNIELHSLYTSREPRVVSALQMLKQHLFKYQG---HIGAYLIVAGVDPTGSHLFSIHAH 128 Query: 194 GTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 G+ G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 129 GSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 187 >6AVO-B nrPDB Length = 234 Score = 81.3 bits (199), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 57/185 (30%), Positives = 93/185 (50%), Gaps = 4/185 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT FQ G+I+ D+RAT + VA ++ +K+ I P + AG AAD + + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKG-AGLSMGTMICGYTRKEGPTIYYVDSDG 194 S+ LH L VA ++IL +++Y+G G S +I G GP +Y V G Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHVGAS---LIVGGVDLTGPQLYGVHPHG 117 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + + +GSGQ A VL+ ++ ++++E A L ++ A D SGG+V+ Sbjct: 118 SYSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACV 177 Query: 255 VTEDG 259 +T+ G Sbjct: 178 ITKTG 182 >3UNH-H nrPDB Length = 234 Score = 78.2 bits (191), Expect = 4e-15, Method: Compositional matrix adjust. Identities = 55/185 (29%), Positives = 91/185 (49%), Gaps = 4/185 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT F+ G+I+ D+RAT + VA ++ +K+ I P + AG AAD + Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKG-AGLSMGTMICGYTRKEGPTIYYVDSDG 194 S+ LH L VA ++IL +++Y+G G S ++ G GP +Y V G Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHVGAS---LVVGGVDLNGPQLYEVHPHG 117 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + + +GSGQ A +L+ ++ ++++E A L +I A D SGG+V+ Sbjct: 118 SYSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACV 177 Query: 255 VTEDG 259 +T G Sbjct: 178 ITAGG 182 >5MPC-h nrPDB Length = 215 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 53/191 (27%), Positives = 92/191 (48%), Gaps = 2/191 (1%) Query: 69 KIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQ 128 K +++ GT+ +A F+ G+I+ DSR T G ++A++ K+ ++ + +G AAD Q Sbjct: 13 KGEVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSAADTQ 72 Query: 129 FWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIY 188 + L+ + S A+ + L Y+ K L+ G ++ GY K +Y Sbjct: 73 AIADIVQYHLELYT-SQYGTPSTETAASVFKELCYENKD-NLTAGIIVAGYDDKNKGEVY 130 Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 + G+ K GSG TF YG D N++ ++S E+ + K S+ A D SGG Sbjct: 131 TIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDGSSGG 190 Query: 249 SVNLYHVTEDG 259 + + +T G Sbjct: 191 VIRMVVLTAAG 201 >6HV7-H nrPDB Length = 226 Score = 77.8 bits (190), Expect = 5e-15, Method: Compositional matrix adjust. Identities = 54/178 (30%), Positives = 90/178 (50%), Gaps = 4/178 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT FQ G+I+ D+RAT + VA ++ +K+ I P + AG AAD + +G Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGT-MICGYTRKEGPTIYYVDSDG 194 S LH L V +A ++L +++Y+G +G +I G ++ + + G Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFKYQG---HIGAYLIVAGVDPTGSHLFSIHAHG 117 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 + G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 118 STDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 175 >3UNF-N nrPDB Length = 199 Score = 77.4 bits (189), Expect = 6e-15, Method: Compositional matrix adjust. Identities = 57/185 (30%), Positives = 95/185 (51%), Gaps = 4/185 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A F GG++V DSR +AG V ++ K+ ++ + ++G AAD Q Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 Q LH L +E V AA+ ++ N+ Y+Y+ L ++ G+ ++EG +Y + G Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYR-EDLLAHLIVAGWDQREGGQVY--GTMGG 117 Query: 196 RLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 L F + GSG ++ YG +D+ YK ++ E+ +I A +RD SGG + L Sbjct: 118 MLIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYLVT 177 Query: 255 VTEDG 259 +T G Sbjct: 178 ITAAG 182 >6EPF-2 nrPDB Length = 277 Score = 77.4 bits (189), Expect = 7e-15, Method: Compositional matrix adjust. Identities = 55/211 (26%), Positives = 97/211 (45%), Gaps = 6/211 (2%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134 GTT ++ GI++ D+RAT G VA + K+ I+P + AG AAD + Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194 S LH L V A+++L ++++Y+ G ++ G GP +Y + G Sbjct: 103 SSNLELHSLTTGRLPRVVTANRMLKQMLFRYQ--GYIGAALVLGGVDVTGPHLYSIYPHG 160 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + K +GSG A V + ++ D+ E+A L +I A D SG +++L Sbjct: 161 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDLCV 220 Query: 255 VTEDGWIYHGNHDV----GELFWKVKEEEGS 281 +++ + + V G F + + E+G+ Sbjct: 221 ISKSKLDFLRPYSVPNKKGTRFGRYRCEKGT 251 >6HUB-H nrPDB Length = 234 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 50/183 (27%), Positives = 87/183 (47%), Gaps = 2/183 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT ++ GI++ D+RAT G VA + K+ I+P + AG AAD + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 S LH L V A+++L ++++Y+ G ++ G GP +Y + G+ Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQ--GYIGAALVLGGVDVTGPHLYSIYPHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 K +GSG A V + ++ D+ E+A L +I A D SGG+++L + Sbjct: 119 TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDLCVI 178 Query: 256 TED 258 +++ Sbjct: 179 SKN 181 >5L4G-8 nrPDB Length = 277 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 50/184 (27%), Positives = 87/184 (47%), Gaps = 2/184 (1%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134 GTT ++ GI++ D+RAT G VA + K+ I+P + AG AAD + Sbjct: 43 GTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLI 102 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194 S LH L V A+++L ++++Y+ G ++ G GP +Y + G Sbjct: 103 SSNLELHSLSTGRLPRVVTANRMLKQMLFRYQ--GYIGAALVLGGVDVTGPHLYSIYPHG 160 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + K +GSG A V + ++ D+ E+A L +I A D SG +++L Sbjct: 161 STDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDLCV 220 Query: 255 VTED 258 ++++ Sbjct: 221 ISKN 224 >5FMG-I nrPDB Length = 229 Score = 75.5 bits (184), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 49/185 (26%), Positives = 86/185 (46%), Gaps = 2/185 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT Q +I+ D+RAT G VA + K+ I+ + AG A D + WL Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 LH L + V+ L+ +++Y+G + ++ G GP +Y + G+ Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQG--YKVCAIVLGGVDVNGPQLYGIHPHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 +GSG A VL++ Y+ ++++E+ L +I A D SGG+V++ + Sbjct: 119 SCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICVI 178 Query: 256 TEDGW 260 T+D + Sbjct: 179 TKDSY 183 >1Q5R-H nrPDB Length = 294 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 60/223 (26%), Positives = 98/223 (43%), Gaps = 19/223 (8%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 HGTT +A ++GG+++A D RAT GN +AS+ V+ V + + +AG A Sbjct: 64 HGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEYSAAGIAGTAGIAIELVRL 123 Query: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY------TRKEG 184 + +E E ++ + L+++V GA GL++ ++ GY + G Sbjct: 124 FAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAG 183 Query: 185 PTIYYVDSDGTRL--KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHR 242 + Y D G R + VGSG FA L Y D E AL S+ AA Sbjct: 184 RIVSY-DVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADD 242 Query: 243 DAYSGG---SVNLY----HVTEDGWIYHGNHDVGELFWKVKEE 278 D+ +GG + +Y +T+ G ++ EL ++ E Sbjct: 243 DSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 >5FMG-E nrPDB Length = 256 Score = 58.5 bits (140), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 47/207 (22%), Positives = 90/207 (43%), Gaps = 13/207 (6%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + G+I+A + R ++ + +V+K++ I+ + M+G AD + Sbjct: 31 IKLGSTAVGICVNDGVILASERRISS-TLIEKDSVEKLLSIDDHIGCAMSGLMADARTLI 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMG----------TMICGYTR 181 + +C ++ E I++ + +++S L + S ++ G Sbjct: 90 DYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLIGGVD 149 Query: 182 KEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAH 241 K GP ++Y + GT + +GS Q A +L NYK D++ E A L ++L Sbjct: 150 KNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILA-LTVLRQVM 208 Query: 242 RDAYSGGSVNLYHVTE-DGWIYHGNHD 267 D S +V + + + D Y N D Sbjct: 209 EDKLSTSNVEICAIKKSDQTFYKYNTD 235 >5FGE-J nrPDB Length = 198 Score = 57.4 bits (137), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 48/191 (25%), Positives = 83/191 (43%), Gaps = 17/191 (8%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQC 138 L R Q +I+A T G V + K +++P L + AG A D + ++ + Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 139 RLHELREKERISVAA---------ASKILSNLVYQYKGAGLSMGTMICGYTRKEG-PTIY 188 +L+ +RE +S A A I S YQ + +I GY +K+ P +Y Sbjct: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQ-------VNVLIGGYDKKKNKPELY 117 Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 +D GT+++ G + + +LD +Y+ D++ E+ L L K + R Sbjct: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 Query: 249 SVNLYHVTEDG 259 V + V +DG Sbjct: 178 GVIVKIVDKDG 188 >3WXR-K nrPDB Length = 238 Score = 57.0 bits (136), Expect = 9e-09, Method: Compositional matrix adjust. Identities = 48/191 (25%), Positives = 83/191 (43%), Gaps = 17/191 (8%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQC 138 L R Q +I+A T G V + K +++P L + AG A D + ++ + Sbjct: 5 LGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQANI 64 Query: 139 RLHELREKERISVAA---------ASKILSNLVYQYKGAGLSMGTMICGYTRKEG-PTIY 188 +L+ +RE +S A A I S YQ + +I GY +K+ P +Y Sbjct: 65 QLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQ-------VNVLIGGYDKKKNKPELY 117 Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 +D GT+++ G + + +LD +Y+ D++ E+ L L K + R Sbjct: 118 QIDYLGTKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFK 177 Query: 249 SVNLYHVTEDG 259 V + V +DG Sbjct: 178 GVIVKIVDKDG 188 >2Z5C-C nrPDB Length = 262 Score = 56.6 bits (135), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 50/222 (22%), Positives = 105/222 (47%), Gaps = 15/222 (6%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + + G+++ V+ RAT+ + S +++K++EI+ + M+G AD + Sbjct: 33 IKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARSMI 91 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLS-----------MGTMICGYT 180 + H L E I+V + ++ + +L ++ G G S + +I G+ Sbjct: 92 EHARTAAVTHNLYYDEDINVESLTQSVCDLALRF-GEGASGEERLMSRPFGVALLIAGHD 150 Query: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 +G +++ + GT + + +GSG A L + + L++++A L + IL Sbjct: 151 ADDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLK-ILKQV 209 Query: 241 HRDAYSGGSVNLYHVT-EDGWIYHGNHDVGELFWKVKEEEGS 281 + + L +T +DG+ + N EL ++KE+E + Sbjct: 210 MEEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAA 251 >1Q5Q-H nrPDB Length = 235 Score = 56.2 bits (134), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 59/221 (26%), Positives = 97/221 (43%), Gaps = 19/221 (8%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A ++GG+++A D RAT GN +AS+ V+KV + + +AG A Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY------TRKEGPT 186 + +E E ++ + L+++V GA GL++ ++ GY + G Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 187 IYYVDSDGTRL--KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDA 244 + Y D G R + VGSG FA L Y D E AL S+ AA D+ Sbjct: 121 VSY-DVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDS 179 Query: 245 YSGG---SVNLY----HVTEDGWIYHGNHDVGELFWKVKEE 278 +GG + +Y +T+ G ++ EL ++ E Sbjct: 180 ATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 220 >5FMG-N nrPDB Length = 265 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 54/232 (23%), Positives = 93/232 (40%), Gaps = 42/232 (18%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + GT+ +A +++ GI++A D +A+ G++ Q V+++ +IN + +G AD Q+ Sbjct: 6 VVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQYLH 65 Query: 132 TWLGSQCRLHELREKER----ISVAAASKILSNLVYQYKGA--GLSMGTMICG------- 178 L ++ ++ L EK+R + +S + Y K L +I G Sbjct: 66 ELL-TRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQKYD 124 Query: 179 --------YTRKEGPT--------------------IYYVDSDGTRLKGDIFCVGSGQTF 210 YT K I +VD GT D G + F Sbjct: 125 NNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYARYF 184 Query: 211 AYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIY 262 A +L +YK +++ E+A L + RDA S + + VT G Y Sbjct: 185 ALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEY 236 >1G0U-D nrPDB Length = 241 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 49/215 (22%), Positives = 103/215 (47%), Gaps = 10/215 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + + G+++ V+ RAT+ + S +++K++EI+ + M+G AD + Sbjct: 31 IKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARSMI 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLS----MGTMICGYTRKEGPTI 187 + H L E I+V + ++ + +L A +S + +I G+ +G + Sbjct: 90 EHARTAAVTHNLYYDEDINVESLTQSVCDLA---AAAAMSRPFGVALLIAGHDADDGYQL 146 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 ++ + GT + + +GSG A L + + L++++A L + IL + Sbjct: 147 FHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLK-ILKQVMEEKLDE 205 Query: 248 GSVNLYHVT-EDGWIYHGNHDVGELFWKVKEEEGS 281 + L +T +DG+ + N EL ++KE+E + Sbjct: 206 NNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAA 240 >6HE5-A nrPDB Length = 247 Score = 55.1 bits (131), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 38/165 (23%), Positives = 72/165 (43%), Gaps = 7/165 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G T + + + G+I+ D R + + T++K+ +I+ + +G AD + Sbjct: 32 VKRGATAIGIKCKEGVILIADKR-VGSKLLEADTIEKIYKIDEHICAATSGLVADARVLI 90 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 + +++ L E I+V +K + + QY G + +I G E P + Sbjct: 91 DRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVD--EVPKL 148 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLG 232 Y D G L+ +G G+ + Y+ DLS +DA+ LG Sbjct: 149 YETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVLG 193 >3H4P-A nrPDB Length = 264 Score = 54.3 bits (129), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 35/165 (21%), Positives = 78/165 (47%), Gaps = 6/165 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + GTT + + G+++AVD R T+ V ++++K+ +I+ + +G AD + Sbjct: 35 VRRGTTAIGIACKDGVVLAVDRRITS-KLVKIRSIEKIFQIDDHVAAATSGLVADARVLI 93 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 + +++ L E IS+ +K + ++ Y G + +I G + E + Sbjct: 94 DRARLEAQIYRLTYGEEISIEMLAKKICDIKQAYTQHGGVRPFGVSLLIAGIDKNEA-RL 152 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLG 232 + D G ++ +GSG+ +L+ Y+ D+++++ L L Sbjct: 153 FETDPSGALIEYKATAIGSGRPVVMELLEKEYRDDITLDEGLELA 197 >5GJR-F nrPDB Length = 241 Score = 52.8 bits (125), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 37/166 (22%), Positives = 79/166 (47%), Gaps = 9/166 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + + G+ +AV+ R T+ + +++K++EI+ + M+G AD + Sbjct: 31 IKLGSTAIGIQTSEGVCLAVEKRITS-PLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLI 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTM--------ICGYTRKE 183 + + H E ++V + ++ +SNL Q+ G M + G ++ Sbjct: 90 DKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEK 149 Query: 184 GPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDAL 229 GP ++++D GT ++ D +GS A L Y +++++A+ Sbjct: 150 GPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAI 195 >3UNE-I nrPDB Length = 205 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 48/190 (25%), Positives = 84/190 (44%), Gaps = 3/190 (1%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 +G +A + + + +A D R + + +K+ + L +AG A D Q Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66 Query: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKE-GPTIYYVDS 192 L + L+EL+E +I +++NL+Y+ + +I G K P I +D Sbjct: 67 LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126 Query: 193 DGTRLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 G + D F V G+ YG+ +S ++ ++ E +++L A RDA SG V Sbjct: 127 IGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGV- 185 Query: 252 LYHVTEDGWI 261 + HV E I Sbjct: 186 IVHVIEKDKI 195 >4Y8P-I nrPDB Length = 205 Score = 51.2 bits (121), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 3/187 (1%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 +G +A + + +A D R + + S +K+ LG + G A D Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYGHVFLG-ITGLATDVTTLNEM 66 Query: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEG-PTIYYVDS 192 + L++L+E+ I ++++S+ +Y+ + +G ++ G K G P I D Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDL 126 Query: 193 DGTRLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 G + F V G+ +G+ +S Y+ +L ED +++L AA RDA SG Sbjct: 127 IGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAV 186 Query: 252 LYHVTED 258 +Y + +D Sbjct: 187 VYIIKKD 193 >5GJQ-g nrPDB Length = 264 Score = 49.7 bits (117), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 50/216 (23%), Positives = 90/216 (41%), Gaps = 6/216 (2%) Query: 50 ASPQQFLRAHTDDSRNPDCKIK--IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVK 107 ++P F+ + R P + + + GT+ L +F+GG+++A D + G+ + + Sbjct: 26 STPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNIS 85 Query: 108 KVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELR-EKERISVAAASKILSNLVYQYK 166 +++ +N + +G AD Q+ + LG EL + S A L+ +Y + Sbjct: 86 RIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRR 145 Query: 167 GAGLSM-GTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD--L 223 + TM+ G + YVD G + G G A +L + L Sbjct: 146 SKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVL 205 Query: 224 SVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDG 259 S +A L +R + +RDA S + VTE G Sbjct: 206 SQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKG 241 >5VFT-S nrPDB Length = 213 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 9/197 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + +G T LA + IVA D+R + G + ++ K ++ + +G DC Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 + ++ ++++ + ++ A + +LS ++Y + + +I G + +Y D Sbjct: 66 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 125 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD---------LSVEDALYLGKRSILAAAHR 242 G+ + GS +LD+ + LS++ A+ L K ++AA R Sbjct: 126 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 185 Query: 243 DAYSGGSVNLYHVTEDG 259 D Y+G ++ + VT++G Sbjct: 186 DVYTGDALRICIVTKEG 202 >5L4G-U nrPDB Length = 241 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 9/197 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + +G T LA + IVA D+R + G + ++ K ++ + +G DC Sbjct: 34 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 93 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 + ++ ++++ + ++ A + +LS ++Y + + +I G + +Y D Sbjct: 94 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 153 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD---------LSVEDALYLGKRSILAAAHR 242 G+ + GS +LD+ + LS++ A+ L K ++AA R Sbjct: 154 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 213 Query: 243 DAYSGGSVNLYHVTEDG 259 D Y+G ++ + VT++G Sbjct: 214 DVYTGDALRICIVTKEG 230 >6EPF-6 nrPDB Length = 240 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 40/195 (20%), Positives = 87/195 (44%), Gaps = 9/195 (4%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 +G T LA + IVA D+R + G + ++ K ++ + +G DC Sbjct: 35 NGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTKI 94 Query: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSD 193 + ++ ++++ + ++ A + +LS ++Y + + +I G + +Y D Sbjct: 95 IEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDPV 154 Query: 194 GTRLKGDIFCVGSGQTFAYGVLDSNYKWD---------LSVEDALYLGKRSILAAAHRDA 244 G+ + GS +LD+ + L+++ A+ L K ++AA RD Sbjct: 155 GSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERDV 214 Query: 245 YSGGSVNLYHVTEDG 259 Y+G ++ + VT++G Sbjct: 215 YTGDALRICIVTKEG 229 >5FMG-M nrPDB Length = 240 Score = 46.6 bits (109), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 37/196 (18%), Positives = 82/196 (41%), Gaps = 8/196 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I +G T + + +I+A D+R + + ++ K+ ++ + +G +D + Sbjct: 34 IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLH 93 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 + L + +L L + +++L ++Y + ++ G +Y D Sbjct: 94 SLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYD 153 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKW--------DLSVEDALYLGKRSILAAAHRD 243 S G+ + CVGSG +LD+ + + ++ D + K +I +A RD Sbjct: 154 SVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERD 213 Query: 244 AYSGGSVNLYHVTEDG 259 Y+G +Y + + G Sbjct: 214 IYTGDKTLIYVIDKMG 229 >6EPE-7 nrPDB Length = 263 Score = 46.2 bits (108), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 57/231 (24%), Positives = 98/231 (42%), Gaps = 17/231 (7%) Query: 36 QFQRL--APSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDS 93 QF R+ PS + P+++P + + ++NP + GT+ L +F G+++A D Sbjct: 20 QFYRVPSTPSCLMDPMSAPARPI----TRTQNP-----MVTGTSVLGVKFDCGVVIAADM 70 Query: 94 RATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHEL-REKERISVA 152 + G+ + + +++ +N + +G AD Q+ + LG EL + S Sbjct: 71 LGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQVLGQMVIDEELFGDGHSYSPR 130 Query: 153 AASKILSNLVY--QYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTF 210 A L+ +Y + K L +I GY E + YVD G + G G Sbjct: 131 AIHSWLTRAMYSRRSKMNPLWNTKVIGGYAGGES-FLGYVDMLGVAYEAPSLATGYGAYL 189 Query: 211 AYGVLDSNYKWD--LSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDG 259 A +L + LS +A L +R + +RDA S + VTE G Sbjct: 190 AQPLLREVLEKQPVLSQTEARELVERCMRVLYYRDARSYNRFQVATVTEKG 240 >5LF6-M nrPDB Length = 219 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 48/201 (23%), Positives = 84/201 (41%), Gaps = 9/201 (4%) Query: 63 SRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAG 122 ++NP + GT+ L +F+GG+++A D + G+ + + +++ +N + +G Sbjct: 1 TQNP-----MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASG 55 Query: 123 GAADCQFWETWLGSQCRLHELR-EKERISVAAASKILSNLVYQYKGAGLSM-GTMICGYT 180 AD Q+ + LG EL + S A L+ +Y + + TM+ G Sbjct: 56 DYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY 115 Query: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD--LSVEDALYLGKRSILA 238 + YVD G + G G A +L + LS +A L +R + Sbjct: 116 ADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRV 175 Query: 239 AAHRDAYSGGSVNLYHVTEDG 259 +RDA S + VTE G Sbjct: 176 LYYRDARSYNRFQIATVTEKG 196 >2JAY-A nrPDB Length = 291 Score = 45.4 bits (106), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 20/55 (36%), Positives = 36/55 (65%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAA 125 ++ HGTT +A ++ GG+++A D R+T GN ++ + V+KV + + +AG AA Sbjct: 53 QLPHGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAA 107 >6J30-C nrPDB Length = 258 Score = 43.9 bits (102), Expect = 8e-05, Method: Compositional matrix adjust. Identities = 49/212 (23%), Positives = 90/212 (42%), Gaps = 19/212 (8%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I+H T + GI++A + + T+ + +K+ ++N + +AG AD + Sbjct: 29 ISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEI-- 86 Query: 132 TWLGSQCRLHE---LRE-KERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKE 183 L + R+H L+ E I V + LS++ Y G + + GY + Sbjct: 87 --LINTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRY 144 Query: 184 GPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRD 243 G +Y + G VG+ + A +L +YK D+ V+DA+ L +++ Sbjct: 145 GYQLYTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSS 204 Query: 244 AYSGGSVNLYHVTEDGWIYHGNHDVGELFWKV 275 A + Y E I G +D GE++ K+ Sbjct: 205 ALT------YDRLEFATIRKGAND-GEVYQKI 229 >5FMG-B nrPDB Length = 235 Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 33/164 (20%), Positives = 69/164 (42%), Gaps = 6/164 (3%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 +++ + L R + G+I+A + + + + ++ K+ +I+ + AG D + Sbjct: 28 RVSSSSPALGIRAKNGVIIATEKK-SPNELIEENSIFKIQQISEHIGIVYAGMPGDFRVL 86 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPT 186 + + L+ I V KI++++V ++ G + +ICG G Sbjct: 87 LKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICG-VDVYGYH 145 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALY 230 +Y +D G CVG L+ Y D+ +EDA++ Sbjct: 146 LYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIH 189 >5FMG-H nrPDB Length = 252 Score = 42.4 bits (98), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/236 (19%), Positives = 88/236 (37%), Gaps = 55/236 (23%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT + + G+++A DSR ++G +++++ +K+ IN L +G +A Q + Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 136 SQC-----------RLHE-------LREKERISVAA------------------------ 153 C R HE E I + + Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 154 -----------ASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIF 202 + I ++Y LS + GY + + +Y V+ +G+ ++ F Sbjct: 121 KFNDYNPLVENVAHITKKIIYT-NNNFLSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDF 179 Query: 203 CV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTE 257 V GSG + L YK ++ ++ L + A H D SGG + + ++T+ Sbjct: 180 AVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITK 235 >4FZC-A nrPDB Length = 250 Score = 42.0 bits (97), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 32/165 (19%), Positives = 71/165 (43%), Gaps = 6/165 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW- 130 + G T+L + G+++A + ++++ S+T+ KV + P + +G D + Sbjct: 28 VKQGVTSLGIKATNGVVIATEKKSSS-PLAMSETLSKVSLLTPDIGAVYSGMGPDYRVLV 86 Query: 131 ----ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 186 + S R++ ++ V+ +KI+ + +I G+ G + Sbjct: 87 DKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFS 146 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYL 231 +Y VD G+ +G G A L+ + +L +EDA+++ Sbjct: 147 LYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHI 191 >5LEZ-C nrPDB Length = 248 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 30/152 (19%), Positives = 66/152 (43%), Gaps = 5/152 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G+T + R + +++ V+ ++ A +TV+K+ ++ + AG AD + Sbjct: 26 VKKGSTAVGVRGRDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 +C+ H L ++ ++V ++ +++L +Y + + +I G+ P + Sbjct: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNY 219 Y D GT +G G L+ NY Sbjct: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNY 176 >2KU2-A nrPDB Length = 237 Score = 39.7 bits (91), Expect = 0.001, Method: Compositional matrix adjust. Identities = 32/168 (19%), Positives = 77/168 (45%), Gaps = 4/168 (2%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G+T L +F G+++ D + + + +++K+ I+ ++ +G AD + Sbjct: 35 VKKGSTALGMKFANGVLLISDKKVRS-RLIEQNSIEKIQLIDDYVAAVTSGLVADARVLV 93 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYK--GAGLSMG-TMICGYTRKEGPTIY 188 + + ++ +++ K +++ + QY G G ++I + GP ++ Sbjct: 94 DFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQIGPRLF 153 Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSI 236 D GT + +GSG+ L+ YK +L ++A+ LG +++ Sbjct: 154 DCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKAL 201 >5LF3-J nrPDB Length = 201 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 38/153 (24%), Positives = 67/153 (43%), Gaps = 4/153 (2%) Query: 87 IIVAVDSRATAGNWVASQT-VKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELRE 145 ++VA D R A N V + K+ +++ +L G A D + ++ +L+++R Sbjct: 13 VLVASD-RVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNVQLYKMRN 71 Query: 146 KERIS-VAAASKILSNLVYQYKG-AGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFC 203 +S AAA+ NL + + ++ GY EGP +YY+D K Sbjct: 72 GYELSPTAAANFTRRNLADCLRSRTPYHVNLLLAGYDEHEGPALYYMDYLAALAKAPFAA 131 Query: 204 VGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSI 236 G G +LD Y +S E A+ L ++ + Sbjct: 132 HGYGAFLTLSILDRYYTPTISRERAVELLRKCL 164 >5LZP-A nrPDB Length = 242 Score = 37.0 bits (84), Expect = 0.009, Method: Compositional matrix adjust. Identities = 17/49 (34%), Positives = 31/49 (63%) Query: 77 TTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAA 125 T +A ++ GG+++A D R+T GN ++ + V+KV + + +AG AA Sbjct: 2 TIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAA 50 >4YA5-C nrPDB Length = 254 Score = 36.6 bits (83), Expect = 0.014, Method: Compositional matrix adjust. Identities = 34/181 (18%), Positives = 76/181 (41%), Gaps = 8/181 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + GT + + + +++ + R+T T KV +I+ ++ + +G AD + Sbjct: 27 VKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILI 86 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGY-TRKEGPT 186 + + H L ++ ++V ++ ++ + +Y +G + T+I G+ R + P Sbjct: 87 EKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPK 146 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNY---KWDLSVEDALYLGKRSILAAAHRD 243 +Y + G +G L+ NY + +VE+ + L RS+L Sbjct: 147 LYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQTG 206 Query: 244 A 244 A Sbjct: 207 A 207 >5JI2-A nrPDB Length = 184 Score = 36.2 bits (82), Expect = 0.015, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 34/68 (50%), Gaps = 1/68 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEI-NPFLLGTMAGGAADCQFWETWL 134 TT ++ R G +++A D +AT GN V VKKV + N ++ AGG AD Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 135 GSQCRLHE 142 + +H+ Sbjct: 62 ERKLEMHQ 69 >3NZW-E nrPDB Length = 234 Score = 34.3 bits (77), Expect = 0.063, Method: Compositional matrix adjust. Identities = 28/115 (24%), Positives = 50/115 (43%), Gaps = 9/115 (7%) Query: 72 IAHGTTTLAFRFQG-GIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 I G+ T+ R ++VA+ A S KK+I+ + + ++AG A D + Sbjct: 29 IKQGSVTVGLRSNTHAVLVALKRNADE----LSSYQKKIIKCDEHMGLSLAGLAPDARVL 84 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQ----YKGAGLSMGTMICGYTR 181 +L QC L +++V A +L + + Y G +G +I GY + Sbjct: 85 SNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYDK 139 >3NZW-L nrPDB Length = 241 Score = 33.9 bits (76), Expect = 0.086, Method: Compositional matrix adjust. Identities = 42/204 (20%), Positives = 82/204 (40%), Gaps = 18/204 (8%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 +G T L + ++A D+R + S+ KV + ++ + G AAD Sbjct: 27 NGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVKR 86 Query: 134 LGSQCR-LHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDS 192 + + H +++S+ +A++ + +L+Y + + T+I G +Y D Sbjct: 87 FKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFDP 146 Query: 193 DGTRLKGDIFCVGSGQTFAYGVLDS--NYKWD---------------LSVEDALYLGKRS 235 G+ + G+ + LD+ N+K LSVE+ + L + S Sbjct: 147 VGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRDS 206 Query: 236 ILAAAHRDAYSGGSVNLYHVTEDG 259 +A R G + + VT+DG Sbjct: 207 FTSATERHIQVGDGLEILIVTKDG 230 >5FMG-C nrPDB Length = 246 Score = 33.9 bits (76), Expect = 0.090, Method: Compositional matrix adjust. Identities = 45/200 (22%), Positives = 88/200 (44%), Gaps = 11/200 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW- 130 I + + T+ + G+I+ D + + +K+ +I+ + +AG AD Sbjct: 28 INNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILI 87 Query: 131 -ETWLGSQCRLHELREKERIS--VAAASKILSNLVYQYKGA---GLSMGTMICGYTRKEG 184 ++ L +Q L+ E + +S V I + QY G G+S +I GY K+G Sbjct: 88 NQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYT-QYGGLRPYGVSF--LIGGYDTKDG 144 Query: 185 PTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDA 244 +Y+ D G +G+ A VL +K D+++E+ L L +++ + + Sbjct: 145 YQLYHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEI 204 Query: 245 YSGGSVNLYHVT-EDGWIYH 263 + L ++T +DG +Y Sbjct: 205 PKSEKIELAYLTNKDGEVYQ 224 >5FMG-F nrPDB Length = 254 Score = 33.1 bits (74), Expect = 0.16, Method: Compositional matrix adjust. Identities = 31/152 (20%), Positives = 66/152 (43%), Gaps = 11/152 (7%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I GT +A + + ++V+ + + S +K+ +I+ ++ +M+G +D + Sbjct: 29 IKQGTCAVAIKSKDYVVVSGLKKCISK---LSFPQEKIFKIDDYIGISMSGITSDAKVLT 85 Query: 132 TWLGSQCRLHELREKERISV-----AAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 186 ++ ++C H+ E I++ + A K N K A +G MI Y + P Sbjct: 86 KFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKRA-FGVGLMIAAYHNE--PC 142 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSN 218 I+ +G+ + D G+ + L+ N Sbjct: 143 IFETRPNGSYFEYDALSFGARSHASKTYLEKN 174 >6GOP-M nrPDB Length = 246 Score = 32.3 bits (72), Expect = 0.21, Method: Compositional matrix adjust. Identities = 15/63 (23%), Positives = 34/63 (53%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I GT+ ++ ++ G+I+A D+ + G+ + V+++I + + ++G +D Q E Sbjct: 18 IVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISDMQHIE 77 Query: 132 TWL 134 L Sbjct: 78 RLL 80 >5FMG-K nrPDB Length = 195 Score = 31.2 bits (69), Expect = 0.51, Method: Compositional matrix adjust. Identities = 19/71 (26%), Positives = 32/71 (45%) Query: 159 SNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSN 218 NL Y + + +I GY +K+G +Y+ D + G G +LD Sbjct: 87 KNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYLSNMDSVNKGAHGYGAYLVSAILDKY 146 Query: 219 YKWDLSVEDAL 229 Y +L+V++AL Sbjct: 147 YHENLTVDEAL 157 >5XM3-A nrPDB Length = 627 Score = 30.8 bits (68), Expect = 0.78, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 40/92 (43%), Gaps = 15/92 (16%) Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 Y G R G +GSGQ AY + + W+ + +++ G A GG Sbjct: 470 YPGPKGDRQNG----IGSGQVKAYNAITGEFAWEKMEKFSVWGGTT---------ATEGG 516 Query: 249 SVNLYHVTEDGWIYHGNHDVGELFWKVKEEEG 280 V ++ T DG+I + D G+L WK K G Sbjct: 517 LV--FYGTLDGFIKARDADTGKLLWKFKLPSG 546 >1H4I-A nrPDB Length = 599 Score = 30.4 bits (67), Expect = 0.82, Method: Compositional matrix adjust. Identities = 21/78 (26%), Positives = 37/78 (47%), Gaps = 11/78 (14%) Query: 205 GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHG 264 G GQ AY + +YKW+ A++ G + + G + +++ T DG++ Sbjct: 451 GLGQIKAYNAITGDYKWEKMERFAVWGGTMA----------TAGDL-VFYGTLDGYLKAR 499 Query: 265 NHDVGELFWKVKEEEGSF 282 + D G+L WK K G+ Sbjct: 500 DSDTGDLLWKFKIPSGAI 517 >1Q1R-A nrPDB Length = 431 Score = 30.4 bits (67), Expect = 0.96, Method: Compositional matrix adjust. Identities = 18/66 (27%), Positives = 30/66 (45%), Gaps = 3/66 (4%) Query: 144 REKERISVAAASKILSNLVYQYKGAGLSMGTMICGY--TRKEGPTIYYVDSDGTRLKGDI 201 R ER++ S +L ++ G + GT +CG+ + + + DGTRL D+ Sbjct: 183 RVLERVTAPPVSAFYEHL-HREAGVDIRTGTQVCGFEMSTDQQKVTAVLCEDGTRLPADL 241 Query: 202 FCVGSG 207 G G Sbjct: 242 VIAGIG 247 >2D0V-A nrPDB Length = 597 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 25/77 (32%), Positives = 34/77 (44%), Gaps = 11/77 (14%) Query: 204 VGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYH 263 +G GQ AY + + YKW +++ G LA A + G T DG++ Sbjct: 450 LGLGQIKAYNAITNEYKWQHMERFSVWGG---TLATAGNLVFYG--------TLDGFLKA 498 Query: 264 GNHDVGELFWKVKEEEG 280 N D GEL WK K G Sbjct: 499 RNSDTGELVWKHKLPSG 515 >1OFH-G nrPDB Length = 174 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 18/53 (33%), Positives = 27/53 (50%), Gaps = 1/53 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEI-NPFLLGTMAGGAADC 127 TT ++ R G ++V D + + GN V +KV + N +L AGG AD Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADA 53 >4R7Y-A nrPDB Length = 613 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 29/94 (30%), Positives = 41/94 (43%), Gaps = 17/94 (18%) Query: 162 VYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSN--- 218 +Y YK + + G ++ P DGTRL+GDI + G GV S Sbjct: 304 IYGYKEVKKGIALALFGGVSRKLP-------DGTRLRGDIHVLLVGDP---GVAKSQILR 353 Query: 219 YKWDLSVEDALYLGKRS----ILAAAHRDAYSGG 248 Y +L+ GK S + AAA RD ++GG Sbjct: 354 YVANLAPRAIYTSGKSSSAAGLTAAAVRDEFTGG 387 >5EXI-A nrPDB Length = 331 Score = 29.6 bits (65), Expect = 1.5, Method: Compositional matrix adjust. Identities = 13/44 (29%), Positives = 22/44 (50%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINP 114 ++A T+ R+ VA D G W+ + TV+ + E+NP Sbjct: 125 RVADSVRTMGLRYATVTGVARDDLPDGGAWLYAATVRAIKELNP 168 >5LE5-B nrPDB Length = 261 Score = 28.9 bits (63), Expect = 2.5, Method: Compositional matrix adjust. Identities = 36/192 (18%), Positives = 73/192 (38%), Gaps = 5/192 (2%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I H T L G+++A + R +K+ ++N + ++AG +D Sbjct: 28 IGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLT 87 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LSMGTMICGYTRKEGPTI 187 L + + L+ +E I L ++ Y G + + G+ + G + Sbjct: 88 NELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQL 147 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKW-DLSVEDALYLGKRSILAAAHRDAYS 246 Y D G C+G+ A +L +YK +++++ AL L + + S Sbjct: 148 YQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLS 207 Query: 247 GGSVNLYHVTED 258 V + +T + Sbjct: 208 AEKVEIATLTRE 219 >5NYF-A nrPDB Length = 245 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 11/24 (45%), Positives = 16/24 (66%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAG 98 GT +AFR + G++ A D+R AG Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAG 25 >5HJ5-A nrPDB Length = 267 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 21/41 (51%), Gaps = 5/41 (12%) Query: 88 IVAVDSRATAGNWVASQTVKKVIEIN-----PFLLGTMAGG 123 ++ + + A G W A+ VK++ E PF+LG GG Sbjct: 3 LIPLKAAAQVGKWAAAHIVKRINEFQPTAERPFVLGLPTGG 43 >1FUI-A nrPDB Length = 591 Score = 28.1 bits (61), Expect = 4.0, Method: Compositional matrix adjust. Identities = 18/54 (33%), Positives = 28/54 (51%), Gaps = 1/54 (1%) Query: 95 ATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKER 148 A AG VAS K + + +G +AG D F+E+WLG + + ++ E R Sbjct: 163 ARAGLAVASMKGKSYLSLGGVSMG-IAGSIVDHNFFESWLGMKVQAVDMTELRR 215 >1LRW-A nrPDB Length = 600 Score = 28.1 bits (61), Expect = 4.4, Method: Compositional matrix adjust. Identities = 22/76 (28%), Positives = 33/76 (43%), Gaps = 11/76 (14%) Query: 205 GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHG 264 G GQ AY + KW+ +++ G A +GG ++ T DG+I Sbjct: 451 GLGQIKAYDAISGEMKWEKMERFSVWGGTM---------ATAGGLT--FYATLDGFIKAR 499 Query: 265 NHDVGELFWKVKEEEG 280 + D G+L WK K G Sbjct: 500 DSDTGDLLWKFKLPSG 515 >3EG4-A nrPDB Length = 304 Score = 27.3 bits (59), Expect = 6.8, Method: Compositional matrix adjust. Identities = 24/105 (22%), Positives = 44/105 (41%), Gaps = 9/105 (8%) Query: 33 GASQFQRLAPSLTVPPIASPQQFLRAHTD--DSRNPDCKIKIAHGTTTLAFRFQGGIIVA 90 G + Q PS+T P +AS ++ + D D N + ++ G + Sbjct: 10 GTLEAQTQGPSMTKPDLASLEKTIEKAFDERDGINTATRGEVREAVEQSLILLDRGEVRV 69 Query: 91 VDSRATAGNWVASQTVKKVI----EINPFLLGTMAGGAADCQFWE 131 + +A GNW +Q +KK + +NP + + GG +W+ Sbjct: 70 AEKQAD-GNWHVNQWLKKAVLLSFRLNP--MEVIKGGPGQSSWWD 111 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3NZW-K nrPDB 442 e-125 5CZ8-K nrPDB 310 5e-85 5L5A-K nrPDB 298 3e-81 5L64-K nrPDB 294 3e-80 6AVO-C nrPDB 261 2e-70 6EPF-5 nrPDB 260 4e-70 3UNF-K nrPDB 256 7e-69 5LN3-5 nrPDB 255 2e-68 3UNB-K nrPDB 244 5e-65 6EPF-2 nrPDB 237 5e-63 5L4G-8 nrPDB 236 1e-62 6HUB-H nrPDB 232 2e-61 5FMG-L nrPDB 222 2e-58 3H4P-a nrPDB 221 3e-58 6HEC-1 nrPDB 218 2e-57 5FMG-I nrPDB 218 2e-57 6EPE-7 nrPDB 215 2e-56 3UNH-H nrPDB 215 2e-56 6AVO-B nrPDB 214 4e-56 6EPC-1 nrPDB 213 8e-56 5GJQ-a nrPDB 212 1e-55 5GJQ-g nrPDB 212 2e-55 5FGI-H nrPDB 210 6e-55 3IPM-H nrPDB 209 9e-55 6HV7-H nrPDB 207 5e-54 5LEZ-N nrPDB 204 4e-53 5MPC-h nrPDB 203 6e-53 6AVO-A nrPDB 197 3e-51 2Z5C-C nrPDB 196 1e-50 1G0U-D nrPDB 194 4e-50 3H4P-A nrPDB 192 2e-49 3UNE-I nrPDB 189 9e-49 5FMG-E nrPDB 188 2e-48 5LF6-M nrPDB 188 2e-48 5FMG-M nrPDB 188 3e-48 5L4G-U nrPDB 187 4e-48 4Y8P-I nrPDB 187 6e-48 5VFT-S nrPDB 185 2e-47 3UNF-N nrPDB 185 2e-47 6EPF-6 nrPDB 181 3e-46 6J30-C nrPDB 175 2e-44 6HE5-A nrPDB 175 2e-44 5FMG-N nrPDB 171 3e-43 5GJR-F nrPDB 170 4e-43 5FGE-J nrPDB 168 2e-42 3WXR-K nrPDB 167 4e-42 1Q5R-H nrPDB 162 2e-40 2KU2-A nrPDB 161 3e-40 5FMG-H nrPDB 160 7e-40 5FMG-B nrPDB 160 9e-40 4FZC-A nrPDB 159 2e-39 5LEZ-C nrPDB 157 4e-39 1Q5Q-H nrPDB 157 4e-39 2JAY-A nrPDB 125 2e-29 Sequences not found previously or not previously below threshold: 5FMG-J nrPDB 146 1e-35 5LF0-A nrPDB 144 3e-35 5LE5-B nrPDB 143 1e-34 5FMG-C nrPDB 142 2e-34 5FMG-D nrPDB 140 8e-34 3NZW-L nrPDB 138 2e-33 4YA5-C nrPDB 138 2e-33 6GOP-M nrPDB 126 9e-30 5LF3-J nrPDB 123 7e-29 5LZP-A nrPDB 116 1e-26 6FVW-g nrPDB 116 1e-26 5FGG-F nrPDB 116 1e-26 1IRU-A nrPDB 113 6e-26 5T0I-L nrPDB 109 1e-24 5FMG-F nrPDB 109 1e-24 5FMG-K nrPDB 108 2e-24 3NZW-E nrPDB 106 1e-23 6EPD-G nrPDB 100 6e-22 5FMG-G nrPDB 87 1e-17 5L5W-G nrPDB 86 2e-17 5FMG-A nrPDB 85 3e-17 5JI2-A nrPDB 67 8e-12 5LOX-A nrPDB 62 2e-10 5NYF-A nrPDB 62 2e-10 5LOY-A nrPDB 62 3e-10 1OFH-G nrPDB 62 3e-10 4HO7-A nrPDB 62 4e-10 1Q5Q-A nrPDB 58 6e-09 5NYW-A nrPDB 55 3e-08 1M4Y-A nrPDB 51 5e-07 2FHG-A nrPDB 50 9e-07 2Z3B-A nrPDB 49 2e-06 3TY6-A nrPDB 48 5e-06 1MZD-A nrPDB 33 0.14 3N5I-A nrPDB 32 0.23 1RFZ-A nrPDB 32 0.26 2WQK-A nrPDB 30 1.3 6AS7-A nrPDB 30 1.5 2R8U-A nrPDB 30 1.6 3G05-A nrPDB 29 2.9 3CP2-A nrPDB 29 2.9 5US1-A nrPDB 28 4.2 1YM5-A nrPDB 28 5.5 >3NZW-K nrPDB Length = 287 Score = 442 bits (1138), Expect = e-125, Method: Composition-based stats. Identities = 287/287 (100%), Positives = 287/287 (100%) Query: 1 MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHT 60 MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHT Sbjct: 1 MQAIADSFSVPNRLVKELQYDNEQNLESDFVTGASQFQRLAPSLTVPPIASPQQFLRAHT 60 Query: 61 DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTM 120 DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTM Sbjct: 61 DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTM 120 Query: 121 AGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYT 180 AGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYT Sbjct: 121 AGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYT 180 Query: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA Sbjct: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 Query: 241 HRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 HRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 241 HRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 >5CZ8-K nrPDB Length = 221 Score = 310 bits (794), Expect = 5e-85, Method: Composition-based stats. Identities = 220/221 (99%), Positives = 220/221 (99%) Query: 67 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAAD 126 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVK VIEINPFLLGTMAGGAAD Sbjct: 1 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKAVIEINPFLLGTMAGGAAD 60 Query: 127 CQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 186 CQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT Sbjct: 61 CQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 120 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS 246 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS Sbjct: 121 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS 180 Query: 247 GGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 GGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 181 GGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 221 >5L5A-K nrPDB Length = 211 Score = 298 bits (762), Expect = 3e-81, Method: Composition-based stats. Identities = 164/212 (77%), Positives = 189/212 (89%), Gaps = 1/212 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+FQ G+I AVDSRA+AG+++++ V KVIEINP+LLGTM+G AADCQ+WET L Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWETLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +CRL+ LR ERISV+AASK+LSN++ QY+G GLSMG+MICG+ +K GP +YYVD GT Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK-GPGLYYVDEHGT 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 RL G++F GSG T+AYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV Sbjct: 120 RLSGNMFSTGSGNTYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 179 Query: 256 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 180 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 211 >5L64-K nrPDB Length = 211 Score = 294 bits (753), Expect = 3e-80, Method: Composition-based stats. Identities = 174/212 (82%), Positives = 192/212 (90%), Gaps = 1/212 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+F+ G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC FWE L Sbjct: 1 TTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ ++ GP +YYVDS+G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGN 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 R+ G F VGSG +AYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV Sbjct: 120 RISGATFSVGSGSVYAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 179 Query: 256 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 287 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG Sbjct: 180 TEDGWIYHGNHDVGELFWKVKEEEGSFNNVIG 211 >6AVO-C nrPDB Length = 204 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 121/202 (59%), Positives = 160/202 (79%), Gaps = 1/202 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+FQ G+I AVDSRA+AG+++++ V KVIEINP+LLGTM+G AADCQ+WE L Sbjct: 1 TTTLAFKFQHGVIAAVDSRASAGSYISALRVNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +CRL+ LR ERISV+AASK+LSN++ QY+G GLSMG+MICG+ +K GP +YYVD GT Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMCQYRGMGLSMGSMICGWDKK-GPGLYYVDEHGT 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 RL G++F GSG T+AYGV+DS Y+ +LS E+A LG+R+I A HRD+YSGG VN+YH+ Sbjct: 120 RLSGNMFSTGSGNTYAYGVMDSGYRPNLSPEEAYDLGRRAIAYATHRDSYSGGVVNMYHM 179 Query: 256 TEDGWIYHGNHDVGELFWKVKE 277 EDGW+ + DV +L + +E Sbjct: 180 KEDGWVKVESTDVSDLLHQYRE 201 >6EPF-5 nrPDB Length = 263 Score = 260 bits (665), Expect = 4e-70, Method: Composition-based stats. Identities = 136/207 (65%), Positives = 167/207 (80%), Gaps = 1/207 (0%) Query: 69 KIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQ 128 +I++ HGTTTLAF+FQ G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC Sbjct: 53 RIEMLHGTTTLAFKFQHGVIVAADSRATAGPYIASQTVKKVIEINPYLLGTMAGGAADCS 112 Query: 129 FWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIY 188 FWE L QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ ++ GP +Y Sbjct: 113 FWERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLY 171 Query: 189 YVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGG 248 YVDS+G R+ G F VGSG +A+GV+D Y +DL VE+A L +R+I A +RDAYSGG Sbjct: 172 YVDSEGNRISGTAFSVGSGSVYAFGVMDRGYSYDLQVEEAYDLARRAIYQATYRDAYSGG 231 Query: 249 SVNLYHVTEDGWIYHGNHDVGELFWKV 275 +VNLYHV EDGWI + +V +L K Sbjct: 232 AVNLYHVREDGWIRVSSDNVADLHDKY 258 >3UNF-K nrPDB Length = 204 Score = 256 bits (655), Expect = 7e-69, Method: Composition-based stats. Identities = 125/202 (61%), Positives = 160/202 (79%), Gaps = 1/202 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+FQ G+IVAVDSRATAG++++S + KVIEINP+LLGTM+G AADCQ+WE L Sbjct: 1 TTTLAFKFQHGVIVAVDSRATAGSYISSLRMNKVIEINPYLLGTMSGCAADCQYWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +CRL+ LR ERISV+AASK+LSN++ QY+G GLSMG+MICG+ +K GP +YYVD +GT Sbjct: 61 KECRLYYLRNGERISVSAASKLLSNMMLQYRGMGLSMGSMICGWDKK-GPGLYYVDDNGT 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 RL G +F GSG T+AYGV+DS Y+ DLS E+A LG+R+I A HRD YSGG VN+YH+ Sbjct: 120 RLSGQMFSTGSGNTYAYGVMDSGYRQDLSPEEAYDLGRRAIAYATHRDNYSGGVVNMYHM 179 Query: 256 TEDGWIYHGNHDVGELFWKVKE 277 EDGW+ + DV +L +K E Sbjct: 180 KEDGWVKVESSDVSDLLYKYGE 201 >5LN3-5 nrPDB Length = 263 Score = 255 bits (652), Expect = 2e-68, Method: Composition-based stats. Identities = 136/206 (66%), Positives = 165/206 (80%), Gaps = 1/206 (0%) Query: 70 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQF 129 I++ HGTTTLAF+F+ G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC F Sbjct: 54 IEMLHGTTTLAFKFRHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSF 113 Query: 130 WETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYY 189 WE L QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ ++ GP +YY Sbjct: 114 WERLLARQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYY 172 Query: 190 VDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGS 249 VDS+G R+ G F VGSG +AYGV+D Y +DL VE A L +R+I A +RDAYSGG+ Sbjct: 173 VDSEGNRISGATFSVGSGSVYAYGVMDRGYSYDLEVEQAYDLARRAIYQATYRDAYSGGA 232 Query: 250 VNLYHVTEDGWIYHGNHDVGELFWKV 275 VNLYHV EDGWI + +V +L K Sbjct: 233 VNLYHVREDGWIRVSSDNVADLHEKY 258 >3UNB-K nrPDB Length = 205 Score = 244 bits (622), Expect = 5e-65, Method: Composition-based stats. Identities = 133/200 (66%), Positives = 160/200 (80%), Gaps = 1/200 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+F G+IVA DSRATAG ++ASQTVKKVIEINP+LLGTMAGGAADC FWE L Sbjct: 1 TTTLAFKFLHGVIVAADSRATAGAYIASQTVKKVIEINPYLLGTMAGGAADCSFWERLLA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 QCR++ELR KERISVAAASK+L+N+VYQYKG GLSMGTMICG+ ++ GP +YYVDS+G Sbjct: 61 RQCRIYELRNKERISVAAASKLLANMVYQYKGMGLSMGTMICGWDKR-GPGLYYVDSEGN 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 R+ G F VGSG +AYGV+D Y +DL VE+A L +R+I A +RDAYSGG+VNLYHV Sbjct: 120 RISGTAFSVGSGSVYAYGVMDRGYSYDLKVEEAYDLARRAIYQATYRDAYSGGAVNLYHV 179 Query: 256 TEDGWIYHGNHDVGELFWKV 275 EDGWI + +V +L K Sbjct: 180 REDGWIRVSSDNVADLHDKY 199 >6EPF-2 nrPDB Length = 277 Score = 237 bits (604), Expect = 5e-63, Method: Composition-based stats. Identities = 55/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWET 132 GTT ++ GI++ D+RAT G VA + K+ I+P + AG AAD Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100 Query: 133 WLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDS 192 + S LH L V A+++L ++++Y+ G ++ G GP +Y + Sbjct: 101 LISSNLELHSLTTGRLPRVVTANRMLKQMLFRYQ--GYIGAALVLGGVDVTGPHLYSIYP 158 Query: 193 DGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 G+ K +GSG A V + ++ D+ E+A L +I A D SG +++L Sbjct: 159 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKKLVSEAIAAGIFNDLGSGSNIDL 218 Query: 253 YHVTEDGWIYHGNHDV----GELFWKVKEEEGS 281 +++ + + V G F + + E+G+ Sbjct: 219 CVISKSKLDFLRPYSVPNKKGTRFGRYRCEKGT 251 >5L4G-8 nrPDB Length = 277 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 54/213 (25%), Positives = 97/213 (45%), Gaps = 6/213 (2%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWET 132 GTT ++ GI++ D+RAT G VA + K+ I+P + AG AAD Sbjct: 41 KTGTTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQ 100 Query: 133 WLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDS 192 + S LH L V A+++L ++++Y+ G ++ G GP +Y + Sbjct: 101 LISSNLELHSLSTGRLPRVVTANRMLKQMLFRYQ--GYIGAALVLGGVDVTGPHLYSIYP 158 Query: 193 DGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 G+ K +GSG A V + ++ D+ E+A L +I A D SG +++L Sbjct: 159 HGSTDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGSNIDL 218 Query: 253 YHVTEDGWIYHGNHDV----GELFWKVKEEEGS 281 ++++ + + V G + + E+G+ Sbjct: 219 CVISKNKLDFLRPYTVPNKKGTRLGRYRCEKGT 251 >6HUB-H nrPDB Length = 234 Score = 232 bits (591), Expect = 2e-61, Method: Composition-based stats. Identities = 54/210 (25%), Positives = 97/210 (46%), Gaps = 6/210 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT ++ GI++ D+RAT G VA + K+ I+P + AG AAD + Sbjct: 1 TTIAGVVYKDGIVLGADTRATEGMVVADKNCSKIHFISPNIYCCGAGTAADTDMTTQLIS 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 S LH L V A+++L ++++Y+ G ++ G GP +Y + G+ Sbjct: 61 SNLELHSLSTGRLPRVVTANRMLKQMLFRYQ--GYIGAALVLGGVDVTGPHLYSIYPHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 K +GSG A V + ++ D+ E+A L +I A D SGG+++L + Sbjct: 119 TDKLPYVTMGSGSLAAMAVFEDKFRPDMEEEEAKNLVSEAIAAGIFNDLGSGGNIDLCVI 178 Query: 256 TEDGWIYHGNHDV----GELFWKVKEEEGS 281 +++ + + V G + + E+G+ Sbjct: 179 SKNKLDFLRPYTVPNKKGTRLGRYRCEKGT 208 >5FMG-L nrPDB Length = 211 Score = 222 bits (565), Expect = 2e-58, Method: Composition-based stats. Identities = 99/205 (48%), Positives = 144/205 (70%), Gaps = 2/205 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTTLAF+F+ GIIVAVDSRA+ G++++SQ V+K+IEIN +LGTMAGGAADC +WE +LG Sbjct: 1 TTTLAFKFKDGIIVAVDSRASMGSFISSQNVEKIIEINKNILGTMAGGAADCLYWEKYLG 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 +++ELR E+ISV AAS ILSN++YQYKG GL G ++ GY G ++YVD G Sbjct: 61 KIIKIYELRNNEKISVRAASTILSNILYQYKGYGLCCGIILSGYDH-TGFNMFYVDDSGK 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 +++G++F GSG T+AY +LDS Y ++L+++ A+ L + +I A RD SGG V ++H+ Sbjct: 120 KVEGNLFSCGSGSTYAYSILDSAYDYNLNLDQAVELARNAIYHATFRDGGSGGKVRVFHI 179 Query: 256 TEDGW-IYHGNHDVGELFWKVKEEE 279 ++G+ DV +L + E Sbjct: 180 HKNGYDKIIEGEDVFDLHYHYTNPE 204 >3H4P-a nrPDB Length = 219 Score = 221 bits (562), Expect = 3e-58, Method: Composition-based stats. Identities = 58/198 (29%), Positives = 104/198 (52%), Gaps = 1/198 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTT+ +I+A D RA+ GN VA + KK+ +I+ ++ T+AG D Q L Sbjct: 2 TTTVGLICDDAVILATDKRASLGNLVADKEAKKLYKIDDYIAMTIAGSVGDAQAIVRLLI 61 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 ++ +L+++R I A + +LSN+++ + +I GY EG ++ +D G Sbjct: 62 AEAKLYKMRTGRNIPPLACATLLSNILHSSRMFPFLTQIIIGGYDLLEGAKLFSLDPLGG 121 Query: 196 RLKGD-IFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 + GSG AYGVL++ Y D+SVE+ + L ++ +A RD +SG ++L Sbjct: 122 MNEEKTFTATGSGSPIAYGVLEAGYDRDMSVEEGIKLALNALKSAMERDTFSGNGISLAV 181 Query: 255 VTEDGWIYHGNHDVGELF 272 +T+DG + ++ ++ Sbjct: 182 ITKDGVKIFEDEEIEKIL 199 >6HEC-1 nrPDB Length = 202 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 61/203 (30%), Positives = 111/203 (54%), Gaps = 2/203 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TTT+ + G+++A + RAT GN++AS+ KK+ +I + T AG D QF + Sbjct: 1 TTTVGLVCKDGVVMATEKRATMGNFIASKAAKKIYQIADRMAMTTAGSVGDAQFLARIIK 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 + L+E+R + + +V A + + SNL+ Y+ + +I G EG +IY +D G Sbjct: 61 IEANLYEIRRERKPTVRAIATLTSNLLNSYRYFPYLVQLLIGGIDS-EGKSIYSIDPIGG 119 Query: 196 RLKGDIF-CVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 ++ GSG AYGVL+ + ++ V++A+ L R+I +A RD+ SG +++ Sbjct: 120 AIEEKDIVATGSGSLTAYGVLEDRFTPEIGVDEAVELAVRAIYSAMKRDSASGDGIDVVK 179 Query: 255 VTEDGWIYHGNHDVGELFWKVKE 277 +TED + + +V ++ K ++ Sbjct: 180 ITEDEFYQYSPEEVEQILAKFRK 202 >5FMG-I nrPDB Length = 229 Score = 218 bits (556), Expect = 2e-57, Method: Composition-based stats. Identities = 49/192 (25%), Positives = 88/192 (45%), Gaps = 2/192 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT Q +I+ D+RAT G VA + K+ I+ + AG A D + WL Sbjct: 1 TTICGLVCQNAVILGADTRATEGPIVADKNCSKLHYISKNIWCAGAGVAGDLEHTTLWLQ 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 LH L + V+ L+ +++Y+ G + ++ G GP +Y + G+ Sbjct: 61 HNVELHRLNTNTQPRVSMCVSRLTQELFKYQ--GYKVCAIVLGGVDVNGPQLYGIHPHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 +GSG A VL++ Y+ ++++E+ L +I A D SGG+V++ + Sbjct: 119 SCLLPFTALGSGSLNAMAVLEAKYRDNMTIEEGKNLVCEAICAGIFNDLGSGGNVDICVI 178 Query: 256 TEDGWIYHGNHD 267 T+D + + + Sbjct: 179 TKDSYQHIRPYK 190 >6EPE-7 nrPDB Length = 263 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 56/237 (23%), Positives = 97/237 (40%), Gaps = 17/237 (7%) Query: 36 QFQRL--APSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDS 93 QF R+ PS + P+++P + + ++NP + GT+ L +F G+++A D Sbjct: 20 QFYRVPSTPSCLMDPMSAPARPI----TRTQNP-----MVTGTSVLGVKFDCGVVIAADM 70 Query: 94 RATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHEL-REKERISVA 152 + G+ + + +++ +N + +G AD Q+ + LG EL + S Sbjct: 71 LGSYGSLARFRNISRIMRVNDSTMLGASGDYADFQYLKQVLGQMVIDEELFGDGHSYSPR 130 Query: 153 AASKILSNLVYQYK--GAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTF 210 A L+ +Y + L +I GY + YVD G + G G Sbjct: 131 AIHSWLTRAMYSRRSKMNPLWNTKVIGGY-AGGESFLGYVDMLGVAYEAPSLATGYGAYL 189 Query: 211 AYGVLDSNYKWD--LSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGN 265 A +L + LS +A L +R + +RDA S + VTE G G Sbjct: 190 AQPLLREVLEKQPVLSQTEARELVERCMRVLYYRDARSYNRFQVATVTEKGVEIEGP 246 >3UNH-H nrPDB Length = 234 Score = 215 bits (548), Expect = 2e-56, Method: Composition-based stats. Identities = 54/210 (25%), Positives = 96/210 (45%), Gaps = 6/210 (2%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT F+ G+I+ D+RAT + VA ++ +K+ I P + AG AAD + Sbjct: 1 TTIAGLVFRDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADTEMTTRMAA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 S+ LH L VA ++IL +++Y+G +++ G GP +Y V G+ Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHV--GASLVVGGVDLNGPQLYEVHPHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 + +GSGQ A +L+ ++ ++++E A L +I A D SGG+V+ + Sbjct: 119 YSRLPFTALGSGQGAAVALLEDRFQPNMTLEAAQELLVEAITAGILSDLGSGGNVDACVI 178 Query: 256 TEDGWIYHG----NHDVGELFWKVKEEEGS 281 T G + + + + G+ Sbjct: 179 TAGGAKLQRALSTPTEPVQRAGRYRFAPGT 208 >6AVO-B nrPDB Length = 234 Score = 214 bits (545), Expect = 4e-56, Method: Composition-based stats. Identities = 55/189 (29%), Positives = 92/189 (48%), Gaps = 2/189 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT FQ G+I+ D+RAT + VA ++ +K+ I P + AG AAD + + Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEMTTRMVA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 S+ LH L VA ++IL +++Y+G ++I G GP +Y V G+ Sbjct: 61 SKMELHALSTGREPRVATVTRILRQTLFRYQGHV--GASLIVGGVDLTGPQLYGVHPHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 + +GSGQ A VL+ ++ ++++E A L ++ A D SGG+V+ + Sbjct: 119 YSRLPFTALGSGQDAALAVLEDRFQPNMTLEAAQGLLVEAVTAGILGDLGSGGNVDACVI 178 Query: 256 TEDGWIYHG 264 T+ G Sbjct: 179 TKTGAKLLR 187 >6EPC-1 nrPDB Length = 238 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 57/214 (26%), Positives = 104/214 (48%), Gaps = 5/214 (2%) Query: 49 IASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKK 108 +++P A T D N +++ GTT +A +F GG+++ DSR T G+++A++ K Sbjct: 11 VSAPAFGPEALTPDWEN----REVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDK 66 Query: 109 VIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA 168 + I+ + +G AAD Q + Q H + E V A+ + + Y+Y+ Sbjct: 67 LTPIHDHIFCCRSGSAADTQAVADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-E 125 Query: 169 GLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDA 228 L G +I G+ +EG +Y V G ++ GSG ++ YG +D+ Y+ ++ ++ Sbjct: 126 DLMAGIIIAGWDPQEGGQVYSVPMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKDEC 185 Query: 229 LYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIY 262 L ++ A RD SGG + L + + G Sbjct: 186 LQFTANALALAMERDGSSGGVIRLAAIQQSGVER 219 >5GJQ-a nrPDB Length = 239 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 54/192 (28%), Positives = 96/192 (50%), Gaps = 1/192 (0%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 +++ GTT +A +F GG+++ DSR T G+++A++ K+ I+ + +G AAD Q Sbjct: 30 EVSTGTTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAV 89 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYV 190 + Q H + E V A+ + + Y+Y+ L G +I G+ +EG +Y V Sbjct: 90 ADAVTYQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSV 148 Query: 191 DSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 250 G ++ GSG ++ YG +D+ Y+ ++ E+ L ++ A RD SGG + Sbjct: 149 PMGGMMVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVI 208 Query: 251 NLYHVTEDGWIY 262 L + E G Sbjct: 209 RLAAIAESGVER 220 >5GJQ-g nrPDB Length = 264 Score = 212 bits (539), Expect = 2e-55, Method: Composition-based stats. Identities = 54/241 (22%), Positives = 95/241 (39%), Gaps = 14/241 (5%) Query: 36 QFQRLAPSLTVPPIASPQQFLRAHTDDSRNPDCKIK--IAHGTTTLAFRFQGGIIVAVDS 93 QF R+ ++P F+ + R P + + + GT+ L +F+GG+++A D Sbjct: 20 QFYRIP--------STPDSFMDPASALYRGPITRTQNPMVTGTSVLGVKFEGGVVIAADM 71 Query: 94 RATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELR-EKERISVA 152 + G+ + + +++ +N + +G AD Q+ + LG EL + S Sbjct: 72 LGSYGSLARFRNISRIMRVNNSTMLGASGDYADFQYLKQVLGQMVIDEELLGDGHSYSPR 131 Query: 153 AASKILSNLVYQYKGAGLSM-GTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFA 211 A L+ +Y + + TM+ G + YVD G + G G A Sbjct: 132 AIHSWLTRAMYSRRSKMNPLWNTMVIGGYADGESFLGYVDMLGVAYEAPSLATGYGAYLA 191 Query: 212 YGVLDSNYKWD--LSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVG 269 +L + LS +A L +R + +RDA S + VTE G G Sbjct: 192 QPLLREVLEKQPVLSQTEARDLVERCMRVLYYRDARSYNRFQIATVTEKGVEIEGPLSTE 251 Query: 270 E 270 Sbjct: 252 T 252 >5FGI-H nrPDB Length = 244 Score = 210 bits (534), Expect = 6e-55, Method: Composition-based stats. Identities = 57/214 (26%), Positives = 101/214 (47%), Gaps = 7/214 (3%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWET 132 + G T + +F G+++A D+R+T G VA + K+ I+P + AG AAD + Sbjct: 10 STGATIVGVKFNNGVVIAADTRSTQGPIVADKNCAKLHRISPKIWCAGAGTAADTEAVTQ 69 Query: 133 WLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDS 192 +GS LH L V +A ++L +++Y+G + ++ G G ++ + + Sbjct: 70 LIGSNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDP-TGSHLFSIHA 127 Query: 193 DGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNL 252 G+ G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 128 HGSTDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDV 187 Query: 253 YH--VTEDGWI---YHGNHDVGELFWKVKEEEGS 281 + +D Y + E K G+ Sbjct: 188 CVMEIGKDAEYLRNYLTPNVREEKQKSYKFPRGT 221 >3IPM-H nrPDB Length = 217 Score = 209 bits (533), Expect = 9e-55, Method: Composition-based stats. Identities = 54/205 (26%), Positives = 107/205 (52%), Gaps = 3/205 (1%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + GTTT+ + +I+A + R T N++ + KK+ +I+ + T+AG D Q Sbjct: 5 LETGTTTVGITLKDAVIMATERRVTMENFIMHKNGKKLFQIDTYTGMTIAGLVGDAQVLV 64 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 ++ ++ L+ L+ + + + A + +LSN++ Q K + ++ G P ++ +D Sbjct: 65 RYMKAELELYRLQRRVNMPIEAVATLLSNMLNQVKYMPYMVQLLVGGID--TAPHVFSID 122 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 + G ++ GSG F YGVL+S Y ++V++ + L R+I AA RD+ SGG ++ Sbjct: 123 AAGGSVEDIYASTGSGSPFVYGVLESQYSEKMTVDEGVDLVIRAISAAKQRDSASGGMID 182 Query: 252 LYHVT-EDGWIYHGNHDVGELFWKV 275 + +T +DG++ + K+ Sbjct: 183 VAVITRKDGYVQLPTDQIESRIRKL 207 >6HV7-H nrPDB Length = 226 Score = 207 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 58/211 (27%), Positives = 99/211 (46%), Gaps = 7/211 (3%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT FQ G+I+ D+RAT + VA ++ +K+ I P + AG AAD + +G Sbjct: 1 TTIAGLVFQDGVILGADTRATNDSVVADKSCEKIHFIAPKIYCCGAGVAADAEAVTQLIG 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 S LH L V +A ++L +++Y+G + ++ G G ++ + + G+ Sbjct: 61 SNIELHSLYTSREPRVVSALQMLKQHLFKYQGH-IGAYLIVAGVDP-TGSHLFSIHAHGS 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH- 254 G +GSG A VL+S++K DL+ E+A+ L +I A D SG +V++ Sbjct: 119 TDVGYYLSLGSGSLAAMAVLESHWKQDLTKEEAIKLASDAIQAGIWNDLGSGSNVDVCVM 178 Query: 255 -VTEDGWI---YHGNHDVGELFWKVKEEEGS 281 + +D Y + E K G+ Sbjct: 179 EIGKDAEYLRNYLTPNVREEKQKSYKFPRGT 209 >5LEZ-N nrPDB Length = 205 Score = 204 bits (519), Expect = 4e-53, Method: Composition-based stats. Identities = 53/187 (28%), Positives = 92/187 (49%), Gaps = 1/187 (0%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A +F GG+++ DSR T G+++A++ K+ I+ + +G AAD Q + Sbjct: 1 TTIMAVQFDGGVVLGADSRTTTGSYIANRVTDKLTPIHDRIFCCRSGSAADTQAVADAVT 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 Q H + E V A+ + + Y+Y+ L G +I G+ +EG +Y V G Sbjct: 61 YQLGFHSIELNEPPLVHTAASLFKEMCYRYR-EDLMAGIIIAGWDPQEGGQVYSVPMGGM 119 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 ++ GSG ++ YG +D+ Y+ ++ E+ L ++ A RD SGG + L + Sbjct: 120 MVRQSFAIGGSGSSYIYGYVDATYREGMTKEECLQFTANALALAMERDGSSGGVIRLAAI 179 Query: 256 TEDGWIY 262 E G Sbjct: 180 AESGVER 186 >5MPC-h nrPDB Length = 215 Score = 203 bits (517), Expect = 6e-53, Method: Composition-based stats. Identities = 55/209 (26%), Positives = 96/209 (45%), Gaps = 4/209 (1%) Query: 65 NPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGA 124 N K +++ GT+ +A F+ G+I+ DSR T G ++A++ K+ ++ + +G A Sbjct: 9 NRLKKGEVSLGTSIMAVTFKDGVILGADSRTTTGAYIANRVTDKLTRVHDKIWCCRSGSA 68 Query: 125 ADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEG 184 AD Q + L+ + S A+ + L Y+ K L+ G ++ GY K Sbjct: 69 ADTQAIADIVQYHLELYTSQYG-TPSTETAASVFKELCYENKDN-LTAGIIVAGYDDKNK 126 Query: 185 PTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDA 244 +Y + G+ K GSG TF YG D N++ ++S E+ + K S+ A D Sbjct: 127 GEVYTIPLGGSVHKLPYAIAGSGSTFIYGYCDKNFRENMSKEETVDFIKHSLSQAIKWDG 186 Query: 245 YSGGSVNLYHVTEDGWIY--HGNHDVGEL 271 SGG + + +T G + +L Sbjct: 187 SSGGVIRMVVLTAAGVERLIFYPDEYEQL 215 >6AVO-A nrPDB Length = 199 Score = 197 bits (502), Expect = 3e-51, Method: Composition-based stats. Identities = 58/187 (31%), Positives = 93/187 (49%), Gaps = 2/187 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A F GG+++ DSR +AG V ++ K+ ++ + ++G AAD Q Sbjct: 1 TTIMAVEFDGGVVMGSDSRVSAGEAVVNRVFDKLSPLHERIYCALSGSAADAQAVADMAA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 Q LH + +E V AA+ ++ N+ Y+Y+ LS M+ G+ ++EG +Y G Sbjct: 61 YQLELHGIELEEPPLVLAAANVVRNISYKYR-EDLSAHLMVAGWDQREGGQVYGT-LGGM 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 + GSG TF YG +D+ YK +S E+ +I A RD SGG + L + Sbjct: 119 LTRQPFAIGGSGSTFIYGYVDAAYKPGMSPEECRRFTTDAIALAMSRDGSSGGVIYLVTI 178 Query: 256 TEDGWIY 262 T G + Sbjct: 179 TAAGVDH 185 >2Z5C-C nrPDB Length = 262 Score = 196 bits (497), Expect = 1e-50, Method: Composition-based stats. Identities = 47/221 (21%), Positives = 102/221 (46%), Gaps = 13/221 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + + G+++ V+ RAT+ + S +++K++EI+ + M+G AD + Sbjct: 33 IKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARSMI 91 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA----------GLSMGTMICGYTR 181 + H L E I+V + ++ + +L ++ + +I G+ Sbjct: 92 EHARTAAVTHNLYYDEDINVESLTQSVCDLALRFGEGASGEERLMSRPFGVALLIAGHDA 151 Query: 182 KEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAH 241 +G +++ + GT + + +GSG A L + + L++++A L + IL Sbjct: 152 DDGYQLFHAEPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLK-ILKQVM 210 Query: 242 RDAYSGGSVNLYHVTE-DGWIYHGNHDVGELFWKVKEEEGS 281 + + L +T+ DG+ + N EL ++KE+E + Sbjct: 211 EEKLDENNAQLSCITKQDGFKIYDNEKTAELIKELKEKEAA 251 >1G0U-D nrPDB Length = 241 Score = 194 bits (492), Expect = 4e-50, Method: Composition-based stats. Identities = 47/212 (22%), Positives = 100/212 (47%), Gaps = 4/212 (1%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + + G+++ V+ RAT+ + S +++K++EI+ + M+G AD + Sbjct: 31 IKLGSTAIGIATKEGVVLGVEKRATS-PLLESDSIEKIVEIDRHIGCAMSGLTADARSMI 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKG-AGLSMGTMICGYTRKEGPTIYYV 190 + H L E I+V + ++ + +L + +I G+ +G +++ Sbjct: 90 EHARTAAVTHNLYYDEDINVESLTQSVCDLAAAAAMSRPFGVALLIAGHDADDGYQLFHA 149 Query: 191 DSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSV 250 + GT + + +GSG A L + + L++++A L + IL + + Sbjct: 150 EPSGTFYRYNAKAIGSGSEGAQAELLNEWHSSLTLKEAELLVLK-ILKQVMEEKLDENNA 208 Query: 251 NLYHVTE-DGWIYHGNHDVGELFWKVKEEEGS 281 L +T+ DG+ + N EL ++KE+E + Sbjct: 209 QLSCITKQDGFKIYDNEKTAELIKELKEKEAA 240 >3H4P-A nrPDB Length = 264 Score = 192 bits (487), Expect = 2e-49, Method: Composition-based stats. Identities = 38/225 (16%), Positives = 95/225 (42%), Gaps = 11/225 (4%) Query: 46 VPPIASPQQFL---RAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVA 102 + P ++ + + + + + GTT + + G+++AVD R T+ V Sbjct: 6 MVPPSAYDRAITVFSPEGRLYQVEYAREAVRRGTTAIGIACKDGVVLAVDRRITS-KLVK 64 Query: 103 SQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLV 162 ++++K+ +I+ + +G AD + + +++ L E IS+ +K + ++ Sbjct: 65 IRSIEKIFQIDDHVAAATSGLVADARVLIDRARLEAQIYRLTYGEEISIEMLAKKICDIK 124 Query: 163 YQYKGA----GLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSN 218 Y + +I G K ++ D G ++ +GSG+ +L+ Sbjct: 125 QAYTQHGGVRPFGVSLLIAGID-KNEARLFETDPSGALIEYKATAIGSGRPVVMELLEKE 183 Query: 219 YKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYH 263 Y+ D+++++ L L ++ A + +V++ +T + Sbjct: 184 YRDDITLDEGLELAITALTKA--NEDIKPENVDVCIITVKDAQFK 226 >3UNE-I nrPDB Length = 205 Score = 189 bits (481), Expect = 9e-49, Method: Composition-based stats. Identities = 45/187 (24%), Positives = 84/187 (44%), Gaps = 2/187 (1%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 +G +A + + + +A D R + + +K+ + L +AG A D Q Sbjct: 7 NGGAVMAMKGKNCVAIAADRRFGIQAQMVTTDFQKIFPMGDRLYIGLAGLATDVQTVAQR 66 Query: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKE-GPTIYYVDS 192 L + L+EL+E +I +++NL+Y+ + +I G K P I +D Sbjct: 67 LKFRLNLYELKEGRQIKPYTLMSMVANLLYEKRFGPYYTEPVIAGLDPKTFKPFICSLDL 126 Query: 193 DGTRLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 G + D F V G+ YG+ +S ++ ++ E +++L A RDA SG V Sbjct: 127 IGCPMVTDDFVVSGTCSEQMYGMCESLWEPNMDPEHLFETISQAMLNAVDRDAVSGMGVI 186 Query: 252 LYHVTED 258 ++ + +D Sbjct: 187 VHVIEKD 193 >5FMG-E nrPDB Length = 256 Score = 188 bits (478), Expect = 2e-48, Method: Composition-based stats. Identities = 47/210 (22%), Positives = 90/210 (42%), Gaps = 15/210 (7%) Query: 70 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQF 129 I G+T + G+I+A + R ++ + +V+K++ I+ + M+G AD + Sbjct: 29 GAIKLGSTAVGICVNDGVILASERRISS-TLIEKDSVEKLLSIDDHIGCAMSGLMADART 87 Query: 130 WETWLGSQCRLHELREKERISVAAASKILSNLVYQYKG-----------AGLSMGTMICG 178 + +C ++ E I++ + +++S L + + +I G Sbjct: 88 LIDYARVECNHYKFIYNENINIKSCVELISELALDFSNLSDSKRKKIMSRPFGVALLI-G 146 Query: 179 YTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILA 238 K GP ++Y + GT + +GS Q A +L NYK D++ E A L ++L Sbjct: 147 GVDKNGPCLWYTEPSGTNTRFSAASIGSAQEGAELLLQENYKKDMTFEQAEILAL-TVLR 205 Query: 239 AAHRDAYSGGSVNLYHVTE-DGWIYHGNHD 267 D S +V + + + D Y N D Sbjct: 206 QVMEDKLSTSNVEICAIKKSDQTFYKYNTD 235 >5LF6-M nrPDB Length = 219 Score = 188 bits (477), Expect = 2e-48, Method: Composition-based stats. Identities = 49/212 (23%), Positives = 85/212 (40%), Gaps = 9/212 (4%) Query: 63 SRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAG 122 ++NP + GT+ L +F+GG+++A D + G+ + + +++ +N + +G Sbjct: 1 TQNP-----MVTGTSVLGVKFEGGVVIAADMLGSYGSLARFRNISRIMRVNNSTMLGASG 55 Query: 123 GAADCQFWETWLGSQCRLHELR-EKERISVAAASKILSNLVYQYKGAGLSM-GTMICGYT 180 AD Q+ + LG EL + S A L+ +Y + + TM+ G Sbjct: 56 DYADFQYLKQVLGQMVIDEELLGDGHSYSPRAIHSWLTRAMYSRRSKMNPLWNTMVIGGY 115 Query: 181 RKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD--LSVEDALYLGKRSILA 238 + YVD G + G G A +L + LS +A L +R + Sbjct: 116 ADGESFLGYVDMLGVAYEAPSLATGYGAYLAQPLLREVLEKQPVLSQTEARDLVERCMRV 175 Query: 239 AAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGE 270 +RDA S + VTE G G Sbjct: 176 LYYRDARSYNRFQIATVTEKGVEIEGPLSTET 207 >5FMG-M nrPDB Length = 240 Score = 188 bits (477), Expect = 3e-48, Method: Composition-based stats. Identities = 37/196 (18%), Positives = 82/196 (41%), Gaps = 8/196 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I +G T + + +I+A D+R + + ++ K+ ++ + +G +D + Sbjct: 34 IDNGGTVIGLTGKDYVILAADTRLSLSYSIYTRFCPKISKLTDKCIIGSSGMQSDIKTLH 93 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 + L + +L L + +++L ++Y + ++ G +Y D Sbjct: 94 SLLQKKIQLFVLEHSHYPDIHVIARLLCVILYSRRFFPYYAFNILAGVDENNKGVLYNYD 153 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKW--------DLSVEDALYLGKRSILAAAHRD 243 S G+ + CVGSG +LD+ + + ++ D + K +I +A RD Sbjct: 154 SVGSYCEATHSCVGSGSQLILPILDNRVEQKNQLIKNTNFNLGDDINFVKDAITSATERD 213 Query: 244 AYSGGSVNLYHVTEDG 259 Y+G +Y + + G Sbjct: 214 IYTGDKTLIYVIDKMG 229 >5L4G-U nrPDB Length = 241 Score = 187 bits (475), Expect = 4e-48, Method: Composition-based stats. Identities = 44/222 (19%), Positives = 95/222 (42%), Gaps = 12/222 (5%) Query: 50 ASPQQFLRAHTDDSRNPDC---KIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTV 106 ++P + L + P + +G T LA + IVA D+R + G + ++ Sbjct: 9 SAPGRDLGMEPHRAAGPLQLRFSPYVFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDS 68 Query: 107 KKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYK 166 K ++ + +G DC + ++ ++++ + ++ A + +LS ++Y + Sbjct: 69 PKCYKLTDKTVIGCSGFHGDCLTLTKIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRR 128 Query: 167 GAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD---- 222 + +I G + +Y D G+ + GS +LD+ + Sbjct: 129 FFPYYVYNIIGGLDEEGKGAVYSFDPVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQN 188 Query: 223 -----LSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDG 259 LS++ A+ L K ++AA RD Y+G ++ + VT++G Sbjct: 189 VEHVPLSLDRAMRLVKDVFISAAERDVYTGDALRICIVTKEG 230 >4Y8P-I nrPDB Length = 205 Score = 187 bits (474), Expect = 6e-48, Method: Composition-based stats. Identities = 43/193 (22%), Positives = 84/193 (43%), Gaps = 3/193 (1%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETW 133 +G +A + + +A D R + + S +K+ + + G A D Sbjct: 8 NGGIVVAMTGKDCVAIACDLRLGSQSLGVSNKFEKIFHYG-HVFLGITGLATDVTTLNEM 66 Query: 134 LGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEG-PTIYYVDS 192 + L++L+E+ I ++++S+ +Y+ + +G ++ G K G P I D Sbjct: 67 FRYKTNLYKLKEERAIEPETFTQLVSSSLYERRFGPYFVGPVVAGINSKSGKPFIAGFDL 126 Query: 193 DGTRLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 G + F V G+ +G+ +S Y+ +L ED +++L AA RDA SG Sbjct: 127 IGCIDEAKDFIVSGTASDQLFGMCESLYEPNLEPEDLFETISQALLNAADRDALSGWGAV 186 Query: 252 LYHVTEDGWIYHG 264 +Y + +D + Sbjct: 187 VYIIKKDEVVKRY 199 >5VFT-S nrPDB Length = 213 Score = 185 bits (471), Expect = 2e-47, Method: Composition-based stats. Identities = 41/197 (20%), Positives = 88/197 (44%), Gaps = 9/197 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + +G T LA + IVA D+R + G + ++ K ++ + +G DC Sbjct: 6 VFNGGTILAIAGEDFAIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLT 65 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 + ++ ++++ + ++ A + +LS ++Y + + +I G + +Y D Sbjct: 66 KIIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIGGLDEEGKGAVYSFD 125 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLDSNYKWD---------LSVEDALYLGKRSILAAAHR 242 G+ + GS +LD+ + LS++ A+ L K ++AA R Sbjct: 126 PVGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLSLDRAMRLVKDVFISAAER 185 Query: 243 DAYSGGSVNLYHVTEDG 259 D Y+G ++ + VT++G Sbjct: 186 DVYTGDALRICIVTKEG 202 >3UNF-N nrPDB Length = 199 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 55/187 (29%), Positives = 94/187 (50%), Gaps = 2/187 (1%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A F GG++V DSR +AG V ++ K+ ++ + ++G AAD Q Sbjct: 1 TTIMAVEFDGGVVVGSDSRVSAGTAVVNRVFDKLSPLHQRIFCALSGSAADAQAIADMAA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT 195 Q LH L +E V AA+ ++ N+ Y+Y+ L ++ G+ ++EG +Y G Sbjct: 61 YQLELHGLELEEPPLVLAAANVVKNISYKYR-EDLLAHLIVAGWDQREGGQVYGT-MGGM 118 Query: 196 RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHV 255 ++ GSG ++ YG +D+ YK ++ E+ +I A +RD SGG + L + Sbjct: 119 LIRQPFTIGGSGSSYIYGYVDAAYKPGMTPEECRRFTTNAITLAMNRDGSSGGVIYLVTI 178 Query: 256 TEDGWIY 262 T G + Sbjct: 179 TAAGVDH 185 >6EPF-6 nrPDB Length = 240 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 87/196 (44%), Gaps = 9/196 (4%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWET 132 +G T LA + IVA D+R + G + ++ K ++ + +G DC Sbjct: 34 FNGGTVLAIAGEDFSIVASDTRLSEGFSIHTRDSPKCYKLTDKTVIGCSGFHGDCLTLTK 93 Query: 133 WLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDS 192 + ++ ++++ + ++ A + +LS ++Y + + +I G + +Y D Sbjct: 94 IIEARLKMYKHSNNKAMTTGAIAAMLSTILYSRRFFPYYVYNIIEGLDEEGKGAVYSFDP 153 Query: 193 DGTRLKGDIFCVGSGQTFAYGVLDSNYKWD---------LSVEDALYLGKRSILAAAHRD 243 G+ + GS +LD+ + L+++ A+ L K ++AA RD Sbjct: 154 VGSYQRDSFKAGGSASAMLQPLLDNQVGFKNMQNVEHVPLTLDRAMRLVKDVFISAAERD 213 Query: 244 AYSGGSVNLYHVTEDG 259 Y+G ++ + VT++G Sbjct: 214 VYTGDALRICIVTKEG 229 >6J30-C nrPDB Length = 258 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 84/213 (39%), Gaps = 10/213 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I+H T + GI++A + + T+ + +K+ ++N + +AG AD + Sbjct: 29 ISHAGTAIGIMASDGIVLAAERKVTSTLLEQDTSTEKLYKLNDKIAVAVAGLTADAEILI 88 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEGPTI 187 + + E I V + LS++ Y + + GY + G + Sbjct: 89 NTARIHAQNYLKTYNEDIPVEILVRRLSDIKQGYTQHGGLRPFGVSFIYAGYDDRYGYQL 148 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Y + G VG+ + A +L +YK D+ V+DA+ L +++ A + Sbjct: 149 YTSNPSGNYTGWKAISVGANTSAAQTLLQMDYKDDMKVDDAIELALKTLSKTTDSSALTY 208 Query: 248 GSVNLYHVTE---DGWIY---HGNHDVGELFWK 274 + + + DG +Y ++ ++ K Sbjct: 209 DRLEFATIRKGANDGEVYQKIFKPQEIKDILVK 241 >6HE5-A nrPDB Length = 247 Score = 175 bits (444), Expect = 2e-44, Method: Composition-based stats. Identities = 39/215 (18%), Positives = 84/215 (39%), Gaps = 8/215 (3%) Query: 69 KIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQ 128 + + G T + + + G+I+ D R + + + T++K+ +I+ + +G AD + Sbjct: 29 REAVKRGATAIGIKCKEGVILIADKRVGS-KLLEADTIEKIYKIDEHICAATSGLVADAR 87 Query: 129 FWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEG 184 + +++ L E I+V +K + + QY + +I G Sbjct: 88 VLIDRARIEAQINRLTYDEPITVKELAKKICDFKQQYTQYGGVRPFGVSLLIAGVDEV-- 145 Query: 185 PTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDA 244 P +Y D G L+ +G G+ + Y+ DLS +DA+ LG ++ + + Sbjct: 146 PKLYETDPSGALLEYKATAIGMGRNAVTEFFEKEYRDDLSFDDAMVLGLVAMGLSIESEL 205 Query: 245 YSGGS-VNLYHVTEDGWIYHGNHDVGELFWKVKEE 278 V V + + ++ + E Sbjct: 206 VPENIEVGYVKVDDRTFKEVSPEELKPYVERANER 240 >5FMG-N nrPDB Length = 265 Score = 171 bits (433), Expect = 3e-43, Method: Composition-based stats. Identities = 51/238 (21%), Positives = 92/238 (38%), Gaps = 42/238 (17%) Query: 70 IKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQF 129 + GT+ +A +++ GI++A D +A+ G++ Q V+++ +IN + +G AD Q+ Sbjct: 4 GPVVTGTSVIAIKYKHGIMIAADRKASYGSYAKFQNVERIFKINNKTVMGFSGELADAQY 63 Query: 130 WETWLGSQCRLHELREKER----ISVAAASKILSNLVYQYKGA--GLSMGTMICGY---- 179 L ++ ++ L EK+R + +S + Y K L +I G Sbjct: 64 LHELL-TRKNINNLSEKKRKEDMYTPQHYHSYVSRVFYVRKNRIDPLFNNIIIAGINSQK 122 Query: 180 -----------------TRKEGPT--------------IYYVDSDGTRLKGDIFCVGSGQ 208 + I +VD GT D G + Sbjct: 123 YDNNDDNVLLYTNKNNDDEQNEYKNNEEYKEIHKDDLYIGFVDMHGTNFCDDYITTGYAR 182 Query: 209 TFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNH 266 FA +L +YK +++ E+A L + RDA S + + VT G Y + Sbjct: 183 YFALTLLRDHYKDNMTEEEARILINECLRILYFRDATSSNFIQIVKVTSKGVEYEEPY 240 >5GJR-F nrPDB Length = 241 Score = 170 bits (432), Expect = 4e-43, Method: Composition-based stats. Identities = 42/213 (19%), Positives = 93/213 (43%), Gaps = 11/213 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I G+T + + G+ +AV+ R T+ + +++K++EI+ + M+G AD + Sbjct: 31 IKLGSTAIGIQTSEGVCLAVEKRITS-PLMEPSSIEKIVEIDAHIGCAMSGLIADAKTLI 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTM--------ICGYTRKE 183 + + H E ++V + ++ +SNL Q+ G M + G ++ Sbjct: 90 DKARVETQNHWFTYNETMTVESVTQAVSNLALQFGEEDADPGAMSRPFGVALLFGGVDEK 149 Query: 184 GPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRD 243 GP ++++D GT ++ D +GS A L Y +++++A+ IL + Sbjct: 150 GPQLFHMDPSGTFVQCDARAIGSASEGAQSSLQEVYHKSMTLKEAIK-SSLIILKQVMEE 208 Query: 244 AYSGGSVNLYHVTEDGWIY-HGNHDVGELFWKV 275 + ++ L V + ++ E+ + Sbjct: 209 KLNATNIELATVQPGQNFHMFTKEELEEVIKDI 241 >5FGE-J nrPDB Length = 198 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 82/191 (42%), Gaps = 3/191 (1%) Query: 78 TLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQ 137 L R Q +I+A T G V + K +++P L + AG A D + ++ + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 138 CRLHELREKERISVAAASKILSNLVYQ--YKGAGLSMGTMICGYTRK-EGPTIYYVDSDG 194 +L+ +RE +S A S + + + + +I GY +K P +Y +D G Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 T+++ G + + +LD +Y+ D++ E+ L L K + R V + Sbjct: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKI 183 Query: 255 VTEDGWIYHGN 265 V +DG + Sbjct: 184 VDKDGIRQVDD 194 >3WXR-K nrPDB Length = 238 Score = 167 bits (423), Expect = 4e-42, Method: Composition-based stats. Identities = 44/191 (23%), Positives = 82/191 (42%), Gaps = 3/191 (1%) Query: 78 TLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQ 137 L R Q +I+A T G V + K +++P L + AG A D + ++ + Sbjct: 4 ILGIRVQDSVILASSKAVTRGISVLKDSDDKTRQLSPHTLMSFAGEAGDTVQFAEYIQAN 63 Query: 138 CRLHELREKERISVAAASKILSNLVYQ--YKGAGLSMGTMICGYTRK-EGPTIYYVDSDG 194 +L+ +RE +S A S + + + + +I GY +K P +Y +D G Sbjct: 64 IQLYSIREDYELSPQAVSSFVRQELAKSIRSRRPYQVNVLIGGYDKKKNKPELYQIDYLG 123 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 T+++ G + + +LD +Y+ D++ E+ L L K + R V + Sbjct: 124 TKVELPYGAHGYSGFYTFSLLDHHYRPDMTTEEGLDLLKLCVQELEKRMPMDFKGVIVKI 183 Query: 255 VTEDGWIYHGN 265 V +DG + Sbjct: 184 VDKDGIRQVDD 194 >1Q5R-H nrPDB Length = 294 Score = 162 bits (409), Expect = 2e-40, Method: Composition-based stats. Identities = 61/241 (25%), Positives = 101/241 (41%), Gaps = 18/241 (7%) Query: 57 RAHTDDSRNPDCKIKI-AHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPF 115 R+H+ + + HGTT +A ++GG+++A D RAT GN +AS+ V+ V + + Sbjct: 46 RSHSTRGGDGMESGDLAPHGTTIVALTYKGGVLLAGDRRATQGNLIASRDVEAVYVTDEY 105 Query: 116 LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSM 172 +AG A + +E E ++ + L+++V GA GL++ Sbjct: 106 SAAGIAGTAGIAIELVRLFAVELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAV 165 Query: 173 GTMICGY-----TRKEGPTIYYVDSDGTRLK--GDIFCVGSGQTFAYGVLDSNYKWDLSV 225 ++ GY I D G R + VGSG FA L Y D Sbjct: 166 VPLLVGYDLDADDESRAGRIVSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDE 225 Query: 226 EDALYLGKRSILAAAHRDAYSGG---SVNLY----HVTEDGWIYHGNHDVGELFWKVKEE 278 E AL S+ AA D+ +GG + +Y +T+ G ++ EL ++ E Sbjct: 226 ETALRAAIESLYDAADDDSATGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAE 285 Query: 279 E 279 Sbjct: 286 R 286 >2KU2-A nrPDB Length = 237 Score = 161 bits (408), Expect = 3e-40, Method: Composition-based stats. Identities = 30/178 (16%), Positives = 78/178 (43%), Gaps = 6/178 (3%) Query: 69 KIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQ 128 + + G+T L +F G+++ D + + + +++K+ I+ ++ +G AD + Sbjct: 32 REAVKKGSTALGMKFANGVLLISDKKVRS-RLIEQNSIEKIQLIDDYVAAVTSGLVADAR 90 Query: 129 FWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEG 184 + + ++ +++ K +++ + QY + + G + G Sbjct: 91 VLVDFARISAQQEKVTYGSLVNIENLVKRVADQMQQYTQYGGVRPYGVSLIFAGIDQI-G 149 Query: 185 PTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHR 242 P ++ D GT + +GSG+ L+ YK +L ++A+ LG +++ ++ Sbjct: 150 PRLFDCDPAGTINEYKATAIGSGKDAVVSFLEREYKENLPEKEAVTLGIKALKSSLEE 207 >5FMG-H nrPDB Length = 252 Score = 160 bits (405), Expect = 7e-40, Method: Composition-based stats. Identities = 47/237 (19%), Positives = 87/237 (36%), Gaps = 55/237 (23%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT + + G+++A DSR ++G +++++ +K+ IN L +G +A Q + Sbjct: 1 TTIIGIIYDNGVMLACDSRTSSGTFISNKCSRKINRINENLYVCRSGASAHSQKIIEIIK 60 Query: 136 SQC-----------RLH-------ELREKERIS--------------------------- 150 C R H E E I Sbjct: 61 HYCVSMKNENRKKGRFHEGETIYDETTYDEEIDIDSINYLDYNNNNDNNLVTKNKYFYED 120 Query: 151 --------VAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGTRLKGDIF 202 V + I ++Y LS + GY + + +Y V+ +G+ ++ F Sbjct: 121 KFNDYNPLVENVAHITKKIIYTNNNF-LSCALIFGGYDKIKKQQLYAVNLNGSIIEKHDF 179 Query: 203 CV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYHVTED 258 V GSG + L YK ++ ++ L + A H D SGG + + ++T+ Sbjct: 180 AVSGSGSIYIQSYLQDKYKKFMTKKECFNLILNCVKYAMHNDNSSGGLIRIVNITKS 236 >5FMG-B nrPDB Length = 235 Score = 160 bits (404), Expect = 9e-40, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 71/175 (40%), Gaps = 6/175 (3%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 +++ + L R + G+I+A + + + + ++ K+ +I+ + AG D + Sbjct: 28 RVSSSSPALGIRAKNGVIIATEKK-SPNELIEENSIFKIQQISEHIGIVYAGMPGDFRVL 86 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKG----AGLSMGTMICGYTRKEGPT 186 + + L+ I V KI++++V ++ + +ICG G Sbjct: 87 LKRARKEAIRYSLQYGSEILVKELVKIIASIVQEFTQTGGVRPFGLSLLICG-VDVYGYH 145 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAH 241 +Y +D G CVG L+ Y D+ +EDA++ ++ + Sbjct: 146 LYQIDPSGCYFNWMATCVGKDYQNNMSFLEKRYNKDIEIEDAIHTAILTLKESYE 200 >4FZC-A nrPDB Length = 250 Score = 159 bits (401), Expect = 2e-39, Method: Composition-based stats. Identities = 40/217 (18%), Positives = 91/217 (41%), Gaps = 11/217 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G T+L + G+++A + ++++ S+T+ KV + P + +G D + Sbjct: 28 VKQGVTSLGIKATNGVVIATEKKSSS-PLAMSETLSKVSLLTPDIGAVYSGMGPDYRVLV 86 Query: 132 TWLG-----SQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPT 186 S R++ ++ V+ +KI+ + +I G+ G + Sbjct: 87 DKSRKVAHTSYKRIYGEYPPTKLLVSEVAKIMQEATQSGGVRPFGVSLLIAGHDEFNGFS 146 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS 246 +Y VD G+ +G G A L+ + +L +EDA+++ ++ + + ++ Sbjct: 147 LYQVDPSGSYFPWKATAIGKGSVAAKTFLEKRWNDELELEDAIHIALLTLKESVEGE-FN 205 Query: 247 GGSVNLYHVTEDGWIYHG----NHDVGELFWKVKEEE 279 G ++ L + ++ G D G F K+ +E Sbjct: 206 GDTIELAIIGDENPDLLGYTGIPTDKGPRFRKLTSQE 242 >5LEZ-C nrPDB Length = 248 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 82/206 (39%), Gaps = 11/206 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G+T + R + +++ V+ ++ A +TV+K+ ++ + AG AD + Sbjct: 26 VKKGSTAVGVRGRDIVVLGVEKKSVA-KLQDERTVRKICALDDNVCMAFAGLTADARIVI 84 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKG----AGLSMGTMICGYTRKEGPTI 187 +C+ H L ++ ++V ++ +++L +Y + +I G+ P + Sbjct: 85 NRARVECQSHRLTVEDPVTVEYITRYIASLKQRYTQSNGRRPFGISALIVGFDFDGTPRL 144 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVED--ALYLGKRSILAAAHRDAY 245 Y D GT +G G L+ NY + D + L +++L Sbjct: 145 YQTDPSGTYHAWKANAIGRGAKSVREFLEKNYTDEAIETDDLTIKLVIKALLEVVQ---S 201 Query: 246 SGGSVNLYHVTEDG-WIYHGNHDVGE 270 G ++ L + D ++ + Sbjct: 202 GGKNIELAVMRRDQSLKILNPEEIEK 227 >1Q5Q-H nrPDB Length = 235 Score = 157 bits (398), Expect = 4e-39, Method: Composition-based stats. Identities = 58/221 (26%), Positives = 94/221 (42%), Gaps = 17/221 (7%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 TT +A ++GG+++A D RAT GN +AS+ V+KV + + +AG A Sbjct: 1 TTIVALTYKGGVLLAGDRRATQGNLIASRDVEKVYVTDEYSAAGIAGTAGIAIELVRLFA 60 Query: 136 SQCRLHELREKERISVAAASKILSNLVYQYKGA---GLSMGTMICGY-----TRKEGPTI 187 + +E E ++ + L+++V GA GL++ ++ GY I Sbjct: 61 VELEHYEKIEGVPLTFDGKANRLASMVRGNLGAAMQGLAVVPLLVGYDLDADDESRAGRI 120 Query: 188 YYVDSDGTRLK--GDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAY 245 D G R + VGSG FA L Y D E AL S+ AA D+ Sbjct: 121 VSYDVVGGRYEERAGYHAVGSGSLFAKSALKKIYSPDSDEETALRAAIESLYDAADDDSA 180 Query: 246 SGG---SVNLY----HVTEDGWIYHGNHDVGELFWKVKEEE 279 +GG + +Y +T+ G ++ EL ++ E Sbjct: 181 TGGPDLTRGIYPTAVTITQAGAVHVSEETTSELARRIVAER 221 >5FMG-J nrPDB Length = 218 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 43/204 (21%), Positives = 81/204 (39%), Gaps = 14/204 (6%) Query: 74 HGTTTLAFRFQGGIIVAVDSRATAGNWV-ASQTVKKVIEINPFLLGTMAGGAADCQFWET 132 +G L + +A D R A + S K+ ++N + ++G A D Q Sbjct: 8 NGGCVLGMSGSNCVAIACDLRLGANTFTTVSTKFSKIFKMNNNVYVGLSGLATDIQTLYE 67 Query: 133 WLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICG-----YTRKEG--- 184 L + L+E+R+ + V + +LS+++Y + + + ++ G Y +EG Sbjct: 68 ILRYRVNLYEVRQDAEMDVECFANMLSSILYSNRFSPYFVNPIVVGFKLKHYVDEEGEKK 127 Query: 185 ----PTIYYVDSDGTRLKGDIFCV-GSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAA 239 P + D G + + F V G +G+ +S Y D + +L+A Sbjct: 128 VNYEPYLTAYDLIGAKCETRDFVVNGVTSEQLFGMCESLYVKDQDENGLFETISQCLLSA 187 Query: 240 AHRDAYSGGSVNLYHVTEDGWIYH 263 RD SG + +T + I Sbjct: 188 LDRDCISGWGAEVLVLTPEKIIKK 211 >5LF0-A nrPDB Length = 234 Score = 144 bits (364), Expect = 3e-35, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 78/208 (37%), Gaps = 7/208 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 +A G ++ + G+++A + + + ++V KV I + +G D + Sbjct: 29 VAGGAPSVGIKAANGVVLATEKKQKS-ILYDERSVHKVEPITKHIGLVYSGMGPDYRVLV 87 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKG----AGLSMGTMICGYTRKEGPTI 187 + + L +E I A + +++++ +Y + +ICG+ P + Sbjct: 88 HRARKLAQQYYLVYQEPIPTAQLVQRVASVMQEYTQSGGVRPFGVSLLICGWNE-GRPYL 146 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 + D G +G L+ Y DL +EDA++ ++ + + Sbjct: 147 FQSDPSGAYFAWKATAMGKNYVNGKTFLEKRYNEDLELEDAIHTAILTLKES-FEGQMTE 205 Query: 248 GSVNLYHVTEDGWIYHGNHDVGELFWKV 275 ++ + E G+ +V + + Sbjct: 206 DNIEVGICNEAGFRRLTPTEVKDYLAAI 233 >5LE5-B nrPDB Length = 261 Score = 143 bits (360), Expect = 1e-34, Method: Composition-based stats. Identities = 35/192 (18%), Positives = 72/192 (37%), Gaps = 5/192 (2%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I H T L G+++A + R +K+ ++N + ++AG +D Sbjct: 28 IGHAGTCLGILANDGVLLAAERRNIHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLT 87 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEGPTI 187 L + + L+ +E I L ++ Y + + G+ + G + Sbjct: 88 NELRLIAQRYLLQYQEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQL 147 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKW-DLSVEDALYLGKRSILAAAHRDAYS 246 Y D G C+G+ A +L +YK +++++ AL L + + S Sbjct: 148 YQSDPSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTMDVSKLS 207 Query: 247 GGSVNLYHVTED 258 V + +T + Sbjct: 208 AEKVEIATLTRE 219 >5FMG-C nrPDB Length = 246 Score = 142 bits (358), Expect = 2e-34, Method: Composition-based stats. Identities = 38/215 (17%), Positives = 84/215 (39%), Gaps = 8/215 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 I + + T+ + G+I+ D + + +K+ +I+ + +AG AD Sbjct: 28 INNASITIGLITKDGVILGADKVFISKLIDKANNYEKIYKIDKHIFCGVAGLNADANILI 87 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEGPTI 187 + + E V+ + ++ Y + +I GY K+G + Sbjct: 88 NQSRLYAQRYLYNYNEVQPVSQLVVQICDIKQSYTQYGGLRPYGVSFLIGGYDTKDGYQL 147 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Y+ D G +G+ A VL +K D+++E+ L L +++ + + Sbjct: 148 YHTDPSGNYSGWFATAIGTNNLTASSVLKQEWKNDMTLEEGLLLALKTLAKSTDTEIPKS 207 Query: 248 GSVNLYHVT-EDGWI---YHGNHDVGELFWKVKEE 278 + L ++T +DG + Y ++ EL ++ Sbjct: 208 EKIELAYLTNKDGEVYQKYLTEKEIEELIKLYTQK 242 >5FMG-D nrPDB Length = 241 Score = 140 bits (352), Expect = 8e-34, Method: Composition-based stats. Identities = 36/217 (16%), Positives = 86/217 (39%), Gaps = 9/217 (4%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G +A + ++AV+ + +T +K+I+++ AG AD + Sbjct: 26 VKKGGCAVAIKSSNFAVLAVEKK-NIPKLQNPKTTEKLIKLDEHNCLAFAGLNADARVLV 84 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYK----GAGLSMGTMICGYTRKEGPTI 187 +C+ + L E V +K ++ + ++ + T+I G+ + I Sbjct: 85 NKTRLECQRYYLNMDEPAPVDYIAKYVAKVQQKFTHRGGVRPFGIATLIAGFKNNKEICI 144 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Y + G +G L+ NY+ ++ +D ++L ++I S Sbjct: 145 YQTEPSGIYAAWKAQAIGKNAKIVQEFLEKNYQENMEQKDCIFLALKAIFEVVE---LSS 201 Query: 248 GSVNLYHVTEDGWIYHGNHDVGELFWKVKEEEGSFNN 284 +V + +TE + ++ + ++ ++E + NN Sbjct: 202 KNVEVALLTEKDLTFIEEQEINSMV-ELIDQERTKNN 237 >3NZW-L nrPDB Length = 241 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 40/206 (19%), Positives = 81/206 (39%), Gaps = 18/206 (8%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWET 132 +G T L + ++A D+R + S+ KV + ++ + G AAD Sbjct: 26 DNGGTILGIAGEDFAVLAGDTRNITDYSINSRYEPKVFDCGDNIVMSANGFAADGDALVK 85 Query: 133 WLGSQCRLHEL-REKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVD 191 + + + +++S+ +A++ + +L+Y + + T+I G +Y D Sbjct: 86 RFKNSVKWYHFDHNDKKLSINSAARNIQHLLYGKRFFPYYVHTIIAGLDEDGKGAVYSFD 145 Query: 192 SDGTRLKGDIFCVGSGQTFAYGVLD------SNYKWD-----------LSVEDALYLGKR 234 G+ + G+ + LD + Y+ LSVE+ + L + Sbjct: 146 PVGSYEREQCRAGGAAASLIMPFLDNQVNFKNQYEPGTNGKVKKPLKYLSVEEVIKLVRD 205 Query: 235 SILAAAHRDAYSGGSVNLYHVTEDGW 260 S +A R G + + VT+DG Sbjct: 206 SFTSATERHIQVGDGLEILIVTKDGV 231 >4YA5-C nrPDB Length = 254 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 34/213 (15%), Positives = 86/213 (40%), Gaps = 12/213 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + GT + + + +++ + R+T T KV +I+ ++ + +G AD + Sbjct: 27 VKRGTCAVGVKGKNCVVLGCERRSTLKLQDTRITPSKVSKIDSHVVLSFSGLNADSRILI 86 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKG----AGLSMGTMICGYTRK-EGPT 186 + + H L ++ ++V ++ ++ + +Y + T+I G+ + + P Sbjct: 87 EKARVEAQSHRLTLEDPVTVEYLTRYVAGVQQRYTQSGGVRPFGVSTLIAGFDPRDDEPK 146 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNY---KWDLSVEDALYLGKRSILAAAHRD 243 +Y + G +G L+ NY + +VE+ + L RS+L Sbjct: 147 LYQTEPSGIYSSWSAQTIGRNSKTVREFLEKNYDRKEPPATVEECVKLTVRSLLEVVQTG 206 Query: 244 AYSGGSVNLYHVTED-GWIYHGNHDVGELFWKV 275 A ++ + V D + + ++ + ++ Sbjct: 207 A---KNIEITVVKPDSDIVALSSEEINQYVTQI 236 >6GOP-M nrPDB Length = 246 Score = 126 bits (317), Expect = 9e-30, Method: Composition-based stats. Identities = 39/225 (17%), Positives = 88/225 (39%), Gaps = 13/225 (5%) Query: 67 DCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAAD 126 + + I GT+ ++ ++ G+I+A D+ + G+ + V+++I + + ++G +D Sbjct: 13 NTQQPIVTGTSVISMKYDNGVIIAADNLGSYGSLLRFNGVERLIPVGDNTVVGISGDISD 72 Query: 127 CQFWETWLGSQCRLHELRE-----KERISVAAASKILSNLVYQYK--GAGLSMGTMICGY 179 Q E L + +E + + + L+ ++YQ + L ++ G Sbjct: 73 MQHIERLLKDLVTENAYDNPLADAEEALEPSYIFEYLATVMYQRRSKMNPLWNAIIVAGV 132 Query: 180 TRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYK-----WDLSVEDALYLGKR 234 + YV+ G G G A +L +V+ A Sbjct: 133 QSNGDQFLRYVNLLGVTYSSPTLATGFGAHMANPLLRKVVDRESDIPKTTVQVAEEAIVN 192 Query: 235 SILAAAHRDAYSGGSVNLYHVTED-GWIYHGNHDVGELFWKVKEE 278 ++ +RDA S + +L + ++ G + N V + W ++ Sbjct: 193 AMRVLYYRDARSSRNFSLAIIDKNTGLTFKKNLQVENMKWDFAKD 237 >2JAY-A nrPDB Length = 291 Score = 125 bits (315), Expect = 2e-29, Method: Composition-based stats. Identities = 48/227 (21%), Positives = 87/227 (38%), Gaps = 17/227 (7%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 ++ HGTT +A ++ GG+++A D R+T GN ++ + V+KV + + +AG AA + Sbjct: 53 QLPHGTTIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEF 112 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNL--------VYQYKGAGLSMGTMICGYTRK 182 + +E E ++ A L+ + + L G I + Sbjct: 113 ARLYAVELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQ 172 Query: 183 EGPTIYYVDSDGT--RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 I D+ G + VGSG FA + Y + L + ++ AA Sbjct: 173 SAGRIVSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAA 232 Query: 241 HRDAYSGGSVNL-------YHVTEDGWIYHGNHDVGELFWKVKEEEG 280 D+ +GG + + DG + + EL + E Sbjct: 233 DDDSATGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 279 >5LF3-J nrPDB Length = 201 Score = 123 bits (310), Expect = 7e-29, Method: Composition-based stats. Identities = 36/191 (18%), Positives = 76/191 (39%), Gaps = 6/191 (3%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQC 138 + + ++VA D A + K+ +++ +L G A D + ++ Sbjct: 5 IGIQGPDYVLVASDRVAASNIVQMKDDHDKMFKMSEKILLLCVGEAGDTVQFAEYIQKNV 64 Query: 139 RLHELREKERISVAAASKI----LSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194 +L+++R +S AA+ L++ + + ++ GY EGP +YY+D Sbjct: 65 QLYKMRNGYELSPTAAANFTRRNLADCLRSRT--PYHVNLLLAGYDEHEGPALYYMDYLA 122 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSGGSVNLYH 254 K G G +LD Y +S E A+ L ++ + R + + ++ Sbjct: 123 ALAKAPFAAHGYGAFLTLSILDRYYTPTISRERAVELLRKCLEELQKRFILNLPTFSVRI 182 Query: 255 VTEDGWIYHGN 265 + ++G N Sbjct: 183 IDKNGIHDLDN 193 >5LZP-A nrPDB Length = 242 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 45/222 (20%), Positives = 82/222 (36%), Gaps = 17/222 (7%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLG 135 T +A ++ GG+++A D R+T GN ++ + V+KV + + +AG AA + Sbjct: 1 ATIVALKYPGGVVMAGDRRSTQGNMISGRDVRKVYITDDYTATGIAGTAAVAVEFARLYA 60 Query: 136 SQCRLHELREKERISVAAASKILSNL--------VYQYKGAGLSMGTMICGYTRKEGPTI 187 + +E E ++ A L+ + + L G I + I Sbjct: 61 VELEHYEKLEGVPLTFAGKINRLAIMVRGNLAAAMQGLLALPLLAGYDIHASDPQSAGRI 120 Query: 188 YYVDSDGT--RLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAY 245 D+ G + VGSG FA + Y + L + ++ AA D+ Sbjct: 121 VSFDAAGGWNIEEEGYQAVGSGSLFAKSSMKKLYSQVTDGDSGLRVAVEALYDAADDDSA 180 Query: 246 SGGSVNL-------YHVTEDGWIYHGNHDVGELFWKVKEEEG 280 +GG + + DG + + EL + E Sbjct: 181 TGGPDLVRGIFPTAVIIDADGAVDVPESRIAELARAIIESRS 222 >6FVW-g nrPDB Length = 245 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 66/180 (36%), Gaps = 10/180 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + +GTT++ + G++ AV+ T+ V + V K+ ++ + +G D + Sbjct: 28 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 86 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYK----GAGLSMGTMICGYTRKEGPTI 187 + + K I + A + L V + + T I G K G + Sbjct: 87 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVST-IFGGVDKNGAHL 145 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYK---WDLSVEDALYLGKRSILAAAHRDA 244 Y ++ G+ G G+ A L+ LS +A+ + I A H D Sbjct: 146 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA-HEDN 204 >5FGG-F nrPDB Length = 288 Score = 116 bits (290), Expect = 1e-26, Method: Composition-based stats. Identities = 35/180 (19%), Positives = 66/180 (36%), Gaps = 10/180 (5%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + +GTT++ + G++ AV+ T+ V + V K+ ++ + +G D + Sbjct: 31 VENGTTSIGIKCNDGVVFAVEKLITSKLLVPQKNV-KIQVVDRHIGCVYSGLIPDGRHLV 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYK----GAGLSMGTMICGYTRKEGPTI 187 + + K I + A + L V + + T I G K G + Sbjct: 90 NRGREEAASFKKLYKTPIPIPAFADRLGQYVQAHTLYNSVRPFGVST-IFGGVDKNGAHL 148 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYK---WDLSVEDALYLGKRSILAAAHRDA 244 Y ++ G+ G G+ A L+ LS +A+ + I A H D Sbjct: 149 YMLEPSGSYWGYKGAATGKGRQSAKAELEKLVDHHPEGLSAREAVKQAAKIIYLA-HEDN 207 >1IRU-A nrPDB Length = 246 Score = 113 bits (284), Expect = 6e-26, Method: Composition-based stats. Identities = 30/169 (17%), Positives = 58/169 (34%), Gaps = 7/169 (4%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWL 134 G T++A R + ++ + + S TV + +I + M G AD + Sbjct: 36 GLTSVAVRGKDCAVIVTQKKV-PDKLLDSSTVTHLFKITENIGCVMTGMTADSRSQVQRA 94 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEGPTIYYV 190 + + + I V K ++++ Y L ++ G ++GP +Y Sbjct: 95 RYEAANWKYKYGYEIPVDMLCKRIADISQVYTQNAEMRPLGCCMILIGIDEEQGPQVYKC 154 Query: 191 DSDGTRLKGDIFCVGSGQTFAYGVLDSNYKW--DLSVEDALYLGKRSIL 237 D G G QT + L+ K D + E + + Sbjct: 155 DPAGYYCGFKATAAGVKQTESTSFLEKKVKKKFDWTFEQTVETAITCLS 203 >5T0I-L nrPDB Length = 268 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 32/216 (14%), Positives = 82/216 (37%), Gaps = 14/216 (6%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + G+ T+ + + ++ RA + + K++ ++ + ++AG AD + Sbjct: 34 VKQGSATVGLKSKTHAVLVALKRAQSELAAHQK---KILHVDNHIGISIAGLTADARLLC 90 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNL----VYQYKGAGLSMGTMICGYTRKEGPTI 187 ++ +C + V+ ++ + +Y +G +I GY GP I Sbjct: 91 NFMRQECLDSRFVFDRPLPVSRLVSLIGSKTQIPTQRYGRRPYGVGLLIAGYDDM-GPHI 149 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLS--VEDALYLGKRSILAA--AHRD 243 + +G+ A L+ + + + + + G R++ A +D Sbjct: 150 FQTCPSANYFDCRAMSIGARSQSARTYLERHMSEFMECNLNELVKHGLRALRETLPAEQD 209 Query: 244 AYSGGSVNLYHVTED-GWIYHGNHDVGELFWKVKEE 278 + +V++ V +D + + + DV ++E Sbjct: 210 -LTTKNVSIGIVGKDLEFTIYDDDDVSPFLEGLEER 244 >5FMG-F nrPDB Length = 254 Score = 109 bits (273), Expect = 1e-24, Method: Composition-based stats. Identities = 38/241 (15%), Positives = 96/241 (39%), Gaps = 20/241 (8%) Query: 58 AHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTV--KKVIEINPF 115 + I GT +A + + ++V+ + ++ + +K+ +I+ + Sbjct: 15 PEGRLYQVEYASEAIKQGTCAVAIKSKDYVVVSGLKKC-----ISKLSFPQEKIFKIDDY 69 Query: 116 LLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG----LS 171 + +M+G +D + ++ ++C H+ E I++ + + +++ + Sbjct: 70 IGISMSGITSDAKVLTKFMQNECLSHKFLYNENINIESLVRSVADKYQKNTQKSSKRAFG 129 Query: 172 MGTMICGYTRKEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYK--WDLSVEDAL 229 +G MI Y P I+ +G+ + D G+ + L+ N + S+E+ + Sbjct: 130 VGLMIAAY--HNEPCIFETRPNGSYFEYDALSFGARSHASKTYLEKNLHLFEECSLEELI 187 Query: 230 YLGKRSI-LAAAHRDAYSGGSVNLYHVTEDG-WIYHGNHDVGELFWKVK---EEEGSFNN 284 +++ + + + + L V ++ W + + E KVK E+E N Sbjct: 188 LHCLKALKCSLSSESELTISNTALAVVGKNHPWQEISSLQLEEYLSKVKMDAEQEQVEEN 247 Query: 285 V 285 V Sbjct: 248 V 248 >5FMG-K nrPDB Length = 195 Score = 108 bits (270), Expect = 2e-24, Method: Composition-based stats. Identities = 31/169 (18%), Positives = 66/169 (39%), Gaps = 4/169 (2%) Query: 77 TTLAFRFQGGIIVAVDSRATAGNWVASQTVK--KVIEINPFLLGTMAGGAADCQFWETWL 134 T + R +++A D+ + + + + K +I+ + G D + ++ Sbjct: 3 TLIGLRGNNFVVLAADT-YSINSIIKLKNDDNTKFYDIHGNKCLLLGGSIGDRLQFGEFI 61 Query: 135 GSQCRLHELREKERISVAAASKIL-SNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSD 193 L++ + + V + + NL Y + + +I GY +K+G +Y+ D Sbjct: 62 RKNVHLYQYQNNTDMFVKSFAFFTRKNLAYYLRRNPFEVNCLIAGYDKKDGYQLYWCDYL 121 Query: 194 GTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHR 242 + G G +LD Y +L+V++AL + K R Sbjct: 122 SNMDSVNKGAHGYGAYLVSAILDKYYHENLTVDEALDIFKLCFEELKKR 170 >3NZW-E nrPDB Length = 234 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 40/213 (18%), Positives = 83/213 (38%), Gaps = 23/213 (10%) Query: 72 IAHGTTTLAFRFQ-GGIIVA----VDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAAD 126 I G+ T+ R ++VA D ++ KK+I+ + + ++AG A D Sbjct: 29 IKQGSVTVGLRSNTHAVLVALKRNADELSSYQ--------KKIIKCDEHMGLSLAGLAPD 80 Query: 127 CQFWETWLGSQCRLHELREKERISVAAASKILSNLV----YQYKGAGLSMGTMICGYTRK 182 + +L QC L +++V A +L + Y G +G +I GY K Sbjct: 81 ARVLSNYLRQQCNYSSLVFNRKLAVERAGHLLCDKAQKNTQSYGGRPYGVGLLIIGYD-K 139 Query: 183 EGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNY----KWDLSVEDALYLGKRSILA 238 G + G + +G+ A L+ K D + ++ + G +I Sbjct: 140 SGAHLLEFQPSGNVTELYGTAIGARSQGAKTYLERTLDTFIKIDGNPDELIKAGVEAISQ 199 Query: 239 AAHRDAYSGGSVNLYHVTEDG-WIYHGNHDVGE 270 + ++ + ++++ V +D + + V + Sbjct: 200 SLRDESLTVDNLSIAIVGKDTPFTIYDGEAVAK 232 >6EPD-G nrPDB Length = 255 Score = 100 bits (250), Expect = 6e-22, Method: Composition-based stats. Identities = 31/213 (14%), Positives = 70/213 (32%), Gaps = 7/213 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 + + +T + R + G++ V+ + + K++ ++ + +AG AD + Sbjct: 31 VENSSTAIGIRCKDGVVFGVEKLVLSKLYEEGSN-KRLFNVDRHVGMAVAGLLADARSLA 89 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYK----GAGLSMGTMICGYTRKEGPTI 187 + I + + ++ V+ Y M+ Y+ +G + Sbjct: 90 DIAREEASNFRSNFGYNIPLKHLADRVAMYVHAYTLYSAVRPFGCSFMLGSYSVNDGAQL 149 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYSG 247 Y +D G +G + A ++ +++ D + + I Sbjct: 150 YMIDPSGVSYGYWGCAIGKARQAAKTEIEKLQMKEMTCRDVVKEVAKIIYIVHDEVKDKA 209 Query: 248 GSVNLYHVTE--DGWIYHGNHDVGELFWKVKEE 278 + L V E G DV E K +E Sbjct: 210 FELELSWVGELTKGRHEIVPKDVREEAEKYAKE 242 >5FMG-G nrPDB Length = 252 Score = 86.6 bits (213), Expect = 1e-17, Method: Composition-based stats. Identities = 26/164 (15%), Positives = 58/164 (35%), Gaps = 5/164 (3%) Query: 72 IAHGTTTLAFRFQGGIIVAV-DSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 I + T L + GII +S + + ++ +N ++ T +G D + Sbjct: 31 INNNNTALCLECKDGIICCCINSNMDKNKMIKKNSYNRIYHVNNNIIITYSGFDGDARNI 90 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYK----GAGLSMGTMICGYTRKEGPT 186 S+ + I + +S ++ Y + +I + K+ Sbjct: 91 IDRARSEANTYYYNFHTNIPLHILVNRISLYIHAYTLYWHMRPFAASIIISSFNEKDKGD 150 Query: 187 IYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALY 230 IY ++ +G K +G + ++ D++V DA+ Sbjct: 151 IYCIEPNGACYKYSGIVIGKNKEMFKTEIEKKDYKDINVRDAIE 194 >5L5W-G nrPDB Length = 252 Score = 85.8 bits (211), Expect = 2e-17, Method: Composition-based stats. Identities = 31/211 (14%), Positives = 70/211 (33%), Gaps = 11/211 (5%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQC 138 LA R + +V + + TV + I+ + + G D + ++ Sbjct: 43 LAVRGKDCTVVISQKKV-PDKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEA 101 Query: 139 RLHELREKERISVAAASKILSNLVYQYKGA----GLSMGTMICGYTRKEGPTIYYVDSDG 194 + + +K ++NL Y L + + GP+IY D G Sbjct: 102 AEFRYKYGYDMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPAG 161 Query: 195 TRLKGDIFCVGSGQTFAYGVLDSNYKWD----LSVEDALYLGKRSILAAAHRDA--YSGG 248 + G Q L++++K ++ E + + +I +S Sbjct: 162 YYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHMIDALGTEFSKN 221 Query: 249 SVNLYHVTEDGWIYHGNHDVGELFWKVKEEE 279 + + T+D + ++ E + E++ Sbjct: 222 DLEVGVATKDKFFTLSAENIEERLVAIAEQD 252 >5FMG-A nrPDB Length = 260 Score = 85.1 bits (209), Expect = 3e-17, Method: Composition-based stats. Identities = 22/223 (9%), Positives = 63/223 (28%), Gaps = 20/223 (8%) Query: 77 TTLAFRFQGGIIVAVDSR-----ATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFWE 131 T++ + + ++ + + + + + I + +M G DC Sbjct: 38 TSVGVKGENCAVIISQKKMATQYISQDKLLDYNNITNIYNITDEIGCSMVGMPGDCLSMV 97 Query: 132 TWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLS----MGTMICGYTRKEGPTI 187 S+ ++ + + + + Y MI G P + Sbjct: 98 YKARSEASEFLYSNGYNVNAETLCRNICDKIQVYTQHAYMRLHACSGMIIGIDENNKPEL 157 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKW------DLSVEDALY----LGKRSIL 237 + D G +G+ + + VL+ + ++++ + L ++ Sbjct: 158 FKFDPSGFCAGYRACVIGNKEQESISVLERLLEKRKKKIQQETIDEDIRNTTILAIEALQ 217 Query: 238 -AAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVGELFWKVKEEE 279 A S V + + ++ + E + Sbjct: 218 TILAFDLKASEIEVAIVSTKNRNFTQISEKEIDNYLTYIAERD 260 >5JI2-A nrPDB Length = 184 Score = 67.0 bits (162), Expect = 8e-12, Method: Composition-based stats. Identities = 36/172 (20%), Positives = 68/172 (39%), Gaps = 25/172 (14%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEI-NPFLLGTMAGGAADCQFWETWL 134 TT ++ R G +++A D +AT GN V VKKV + N ++ AGG AD Sbjct: 2 TTIVSVRRNGHVVIAGDGQATLGNTVMKGNVKKVRRLYNDKVIAGFAGGTADAFTLFELF 61 Query: 135 GSQCRLHELREKERIS--VAAASKILSNLVYQYKGAGLSM-----GTMICGYTRKEGPTI 187 + +H + + V A ++ + + A L++ +I G P Sbjct: 62 ERKLEMH---QGHLVKAAVELAKDWRTDRMLRKLEALLAVADETASLIITGNGDVVQP-- 116 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAA 239 + D+ +GSG +A + + + A + ++++ A Sbjct: 117 ----------ENDLIAIGSGGPYAQAAARALLEN--TELSAREIAEKALDIA 156 >5LOX-A nrPDB Length = 242 Score = 62.3 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 43/209 (20%), Positives = 69/209 (33%), Gaps = 19/209 (9%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEIN---PFLLGT-MAGGAADCQFWETWL 134 +A G++ A DSR AG T +K+ LL AG A Q L Sbjct: 4 VAMHLADGLVFASDSRTNAG-IDHIATFRKLFTFGTPGERLLVVQTAGNLATSQSVINLL 62 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQY---------KGAGLSMGTMICGYTRKEGP 185 + R SV A+ +++ + LS M+ G P Sbjct: 63 QQRIRRDGASLLNVPSVYDATALVAETTREVMARDSGNLAGNTDLSCSFMVGGQIAGGPP 122 Query: 186 TIYYVDSDGTRLKG----DIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAH 241 +Y + G ++ +G + +LD N +D +E AL S + Sbjct: 123 ALYSIYPQGNFIQATPDTPFLQLGE-SKYGKPILDRNLTFDTPLEQALRCALVSFDSTIR 181 Query: 242 RDAYSGGSVNLYHVTEDGWIYHGNHDVGE 270 + G ++L D I + V E Sbjct: 182 SNLSVGMPLDLLVYHRDSLILPEGYRVTE 210 >5NYF-A nrPDB Length = 245 Score = 62.3 bits (150), Expect = 2e-10, Method: Composition-based stats. Identities = 34/216 (15%), Positives = 78/216 (36%), Gaps = 22/216 (10%) Query: 75 GTTTLAFRFQGGIIVAVDSRATAG--NWVASQTVKKVIEINPFLLGTMA-GGAADCQFWE 131 GT +AFR + G++ A D+R AG N + ++ + + ++ G A Q Sbjct: 2 GTYAVAFRLERGLVFAADTRTNAGVDNIAQYKKLQLWRQPGERVFVLLSAGNLAATQAVV 61 Query: 132 ----TWLGSQCRLHELREKERISVAAASKILSNLVYQYKG----------AGLSMGTMIC 177 L + ++ A++++ + V + + G + + Sbjct: 62 SLINEHLSQETDDEVTTLFTAPNMYRAARVVGDAVREARSIDGAALEASKLGFNTNFIFG 121 Query: 178 GYTRKEGPTIYYVDSDGTRLKG----DIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGK 233 G + E P ++ + +G ++ F +G + +LD + D+ + +A L Sbjct: 122 GQIKGERPRLFQIYPEGNFIEATDDTPFFQIGE-HKYGKPILDRVARSDMRLGEAAKLML 180 Query: 234 RSILAAAHRDAYSGGSVNLYHVTEDGWIYHGNHDVG 269 S + + G ++L D + + Sbjct: 181 LSFDSTLRSNLSVGMPIDLVIYERDTFDVTREKRIS 216 >5LOY-A nrPDB Length = 240 Score = 62.3 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 37/198 (18%), Positives = 71/198 (35%), Gaps = 20/198 (10%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEIN----PFLLGTMAGGAADCQFWETWL 134 + R G++ A DSR AG T +K+ ++ AG A Q + L Sbjct: 4 VGIRLDEGLVFASDSRTNAG-VDNISTFRKMHVFEVPGERVIVLLTAGNLATTQAVISLL 62 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYK----------GAGLSMGTMICGYTRKEG 184 + + E R S+ A++++ + + + G + ++ G E Sbjct: 63 EERLKDPEERLLTAPSMFEAARLVGEALREVQARDAPALEADGVDFNASFILGGQIAGEP 122 Query: 185 PTIYYVDSDGTRLKG----DIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAA 240 P ++ + G ++ F +G + +LD D S+EDA S + Sbjct: 123 PRLFLIYPAGNFIEATPDTPFFQIGE-TKYGKPILDRVITPDTSLEDAAKCALVSFDSTM 181 Query: 241 HRDAYSGGSVNLYHVTED 258 + G ++L D Sbjct: 182 RSNLSVGLPLDLLVYERD 199 >1OFH-G nrPDB Length = 174 Score = 62.0 bits (149), Expect = 3e-10, Method: Composition-based stats. Identities = 34/172 (19%), Positives = 62/172 (36%), Gaps = 24/172 (13%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEI-NPFLLGTMAGGAADCQFWETWL 134 TT ++ R G ++V D + + GN V +KV + N +L AGG AD Sbjct: 1 TTIVSVRRNGQVVVGGDGQVSLGNTVMKGNARKVRRLYNGKVLAGFAGGTADAFTLFELF 60 Query: 135 GSQCRLHELREKERIS--VAAASKILSNLVYQYKGAGLSM-----GTMICGYTRKEGPTI 187 + +H + + V A ++ + A L + +I G P Sbjct: 61 ERKLEMH---QGHLLKSAVELAKDWRTDRALRKLEAMLIVADEKESLIITGIGDVVQPE- 116 Query: 188 YYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAA 239 + I +GSG +A + + + A + ++S+ A Sbjct: 117 ----------EDQILAIGSGGNYALSAARALVEN--TELSAHEIVEKSLRIA 156 >4HO7-A nrPDB Length = 179 Score = 61.6 bits (148), Expect = 4e-10, Method: Composition-based stats. Identities = 34/175 (19%), Positives = 67/175 (38%), Gaps = 16/175 (9%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVK-KVIEINPFLLGTMAGGAADCQFWETWL 134 TT L+ R +++ D + T G + +++ K+ IN ++ AG AD L Sbjct: 1 TTILSVRKGDTVVLLGDRQVTLGERIVAKSSACKLRRINDDVVIGFAGSTADAISLMEKL 60 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194 ++ + +V A + ++ + L ++C +D G Sbjct: 61 ENKIGEFPNQLTRA-AVELAKEWRTDRALRR----LEASLIVCSAEET-----LEIDGQG 110 Query: 195 TRL---KGDIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILAAAHRDAYS 246 + I +GSG TFA + D+ DA + ++++ A D +S Sbjct: 111 NVITPEADGIVAIGSGGTFAKAAARALI--DVDGYDAEKIARKAMRIATDIDVFS 163 >1Q5Q-A nrPDB Length = 259 Score = 57.7 bits (138), Expect = 6e-09, Method: Composition-based stats. Identities = 33/204 (16%), Positives = 76/204 (37%), Gaps = 21/204 (10%) Query: 44 LTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVAS 103 +T+P AS +Q +R ++ +R IA G + + F+ G++ ++ +TA Sbjct: 1 MTMPYYASAEQIMRDRSELARK-----GIARGRSVVVLTFRDGVLFVAENPSTA------ 49 Query: 104 QTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKER-ISVAAASKILSNLV 162 + KV E+ L G + + + R ++ + + + + Sbjct: 50 --LHKVSELYDRLGFAAVGKYNEFENLRRAGIVHADMRGYSYDRRDVTGRSLANAYAQTL 107 Query: 163 ---YQYKGAGLSMGTMIC--GYT-RKEGPTIYYVDSDGTRLKGDIFCV-GSGQTFAYGVL 215 + + + + G + P +Y + DG+ + F V G + Sbjct: 108 GTIFTEQPKPYEVEICVAEVGRVGSPKAPQLYRITYDGSIVDEQHFVVMGGTTEPIATAM 167 Query: 216 DSNYKWDLSVEDALYLGKRSILAA 239 +Y+ DL +E A+ + ++ Sbjct: 168 RESYRADLDLEAAVGIAVNALRQG 191 >5NYW-A nrPDB Length = 251 Score = 55.4 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 35/190 (18%), Positives = 65/190 (34%), Gaps = 23/190 (12%) Query: 79 LAFRFQGGIIVAVDSRATAGNWVASQTVKKVI---EINPFLLGT-MAGGAADCQFWETWL 134 +A R G+ A DSR AG T +K+ + L AG A Q + L Sbjct: 4 VAMRLSSGLAFASDSRTNAG-VDHISTFRKLHLFQQPGERTLVVQSAGNLATTQSIVSLL 62 Query: 135 GSQC------------RLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRK 182 +C ++E +V S G + ++ G + Sbjct: 63 QRRCLDPEQTNLMNVASMYEAATLLGETVREVINRDSGAQQNSHGTDFNCNLLLGGQIKG 122 Query: 183 EGPTIYYVDSDGTRLKG----DIFCVGSGQTFAYGVLDSNYKWDLSVEDALYLGKRSILA 238 EG ++++ G ++ F +G + ++D +D ++ A+ S+ Sbjct: 123 EGLRLFHIYPQGNFIEATQDTPYFQIGE-SKYGKPIIDRVLSYDTPLDQAMQCALISM-D 180 Query: 239 AAHRDAYSGG 248 + R S G Sbjct: 181 STLRSNLSVG 190 >1M4Y-A nrPDB Length = 171 Score = 51.2 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 35/181 (19%), Positives = 71/181 (39%), Gaps = 17/181 (9%) Query: 76 TTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINP-FLLGTMAGGAADCQFWETWL 134 TT L R G ++ D + T G+ V +KV ++ +L AG AD Sbjct: 1 TTILVVRRNGQTVMGGDGQVTFGSTVLKGNARKVRKLGEGKVLAGFAGSVADAMTLFDRF 60 Query: 135 GSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDG 194 ++ R + +V A ++ V + A L + ++ I+ + +G Sbjct: 61 EAKLR-EWGGNLTKAAVELAKDWRTDRVLRRLEALLLVA------DKEN---IFIISGNG 110 Query: 195 TRLK--GDIFCVGSGQTFAYGVLDSNYKW-DLSVEDALYLGKRSILAAAHRDAYSGGSVN 251 ++ D +GSG +A + + DLS A + ++++ A Y+ ++ Sbjct: 111 EVIQPDDDAAAIGSGGPYALAAAKALLRNTDLS---AREIVEKAMTIAGEICIYTNQNIV 167 Query: 252 L 252 + Sbjct: 168 I 168 >2FHG-A nrPDB Length = 250 Score = 50.4 bits (119), Expect = 9e-07, Method: Composition-based stats. Identities = 31/201 (15%), Positives = 72/201 (35%), Gaps = 21/201 (10%) Query: 47 PPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTV 106 P SP+Q +R ++ +R + K + +A + GG++ ++ S+++ Sbjct: 6 PYFISPEQAMRERSELARKGIARAK-----SVVALAYAGGVLFVAEN--------PSRSL 52 Query: 107 KKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELREKER-ISVAAASKILSNLV--- 162 +K+ E+ + AG + R ++ + + + + Sbjct: 53 QKISELYDRVGFAAAGKFNEFDNLRRGGIQFADTRGYAYDRRDVTGRQLANVYAQTLGTI 112 Query: 163 YQYKGAGLSMGTM---ICGYTRKEGPTIYYVDSDGTRLKGDIFCV-GSGQTFAYGVLDSN 218 + + + + Y + P +Y + DG+ F V G L + Sbjct: 113 FTEQAKPYEVELCVAEVAHYGETKRPELYRITYDGSIADEPHFVVMGGTTEPIANALKES 172 Query: 219 YKWDLSVEDALYLGKRSILAA 239 Y + S+ DAL + ++ A Sbjct: 173 YAENASLTDALRIAVAALRAG 193 >2Z3B-A nrPDB Length = 180 Score = 49.2 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 34/173 (19%), Positives = 59/173 (34%), Gaps = 23/173 (13%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAG-NWVASQTVKKVIEI-NPFLLGTMAGGAADCQFW 130 H TT A + +G ++ D + T G V T +KV ++ N +L AG AD Sbjct: 3 FHATTIFAVQHKGRSAMSGDGQVTFGQAVVMKHTARKVRKLFNGKVLAGFAGSVADAFTL 62 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMG-----TMICGYTRKEGP 185 ++ + K +V A + S+ V + A L + ++ G P Sbjct: 63 FEKFEAKLEEYNGNLKRA-AVELAKEWRSDKVLRKLEAMLIVMNQDTLLLVSGTGEVIEP 121 Query: 186 TIYYVDSDGTRLKGDIFCVGSGQTFAYG---VLDSNYKWDLSVEDALYLGKRS 235 I +GSG +A L + +S + + Sbjct: 122 D------------DGILAIGSGGNYALAAGRALKKHAGESMSASEIARAALET 162 >3TY6-A nrPDB Length = 183 Score = 48.1 bits (113), Expect = 5e-06, Method: Composition-based stats. Identities = 29/150 (19%), Positives = 50/150 (33%), Gaps = 24/150 (16%) Query: 73 AHGTTTLAFRFQGGIIVAVDSRATAGNWVA----SQTVKKVIEINPFLLGTMAGGAADCQ 128 H TT A G +A D + T GN V ++ V+K+ + +L AG AD Sbjct: 7 FHATTIFAVHHNGECAMAGDGQVTMGNAVVMKHTARKVRKLFQ--GKVLAGFAGSVADAF 64 Query: 129 FWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSM-----GTMICGYTRKE 183 + + + +V A + + + + A L + ++ G Sbjct: 65 TLFEMFEGKLEEYNGNLQRA-AVEMAKQWRGDKMLRQLEAMLIVMDKTTMLLVSGTGEVI 123 Query: 184 GPTIYYVDSDGTRLKGDIFCVGSGQTFAYG 213 P I +GSG +A Sbjct: 124 EPD------------DGILAIGSGGNYALS 141 >1MZD-A nrPDB Length = 240 Score = 33.1 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 18/83 (21%), Positives = 27/83 (32%), Gaps = 9/83 (10%) Query: 147 ERISVAAASKILSNLVYQYKGAGLSMGTMICGYTRKEGPTIYYVDSDGT-RLKGDIFCVG 205 ++V S+ L N Y G M+C K D+ G KG + Sbjct: 145 REVTVTVLSRKLCNSQSYYNGDPFITKDMVCAGDAKGQKDSCKGDAGGPLICKGVFHAIV 204 Query: 206 SG--------QTFAYGVLDSNYK 220 SG + Y +L Y+ Sbjct: 205 SGGHECGVATKPGIYTLLTKKYQ 227 >3N5I-A nrPDB Length = 373 Score = 32.3 bits (72), Expect = 0.23, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 6/50 (12%) Query: 65 NPDCKIKIAHGTTTLAFRFQGG------IIVAVDSRATAGNWVASQTVKK 108 P + + GT +A+ F+GG ++ A D+R T G V + + Sbjct: 162 GPVAEGNVGGGTGMIAYTFKGGIGTSSRVVSAGDTRYTVGVLVQANHGDR 211 >1RFZ-A nrPDB Length = 168 Score = 32.3 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 20/47 (42%), Gaps = 3/47 (6%) Query: 214 VLDSNYKWDLSVEDALYLGKRSILA-AAHRDAYSGGSVNLYHVTEDG 259 L S Y DL++E+ + R I +G + L + EDG Sbjct: 36 YLQSKYHPDLTMEECIENVNRVISKREVQNAILTG--IQLDKLAEDG 80 >2WQK-A nrPDB Length = 251 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 17/93 (18%), Positives = 36/93 (38%), Gaps = 6/93 (6%) Query: 87 IIVAVDSRATA-GNWVASQTVKKVIEINPFLLGTMAGGAADCQFWETWLGSQCRLHELRE 145 ++VA D + G+ + K+ +I+ + G ADC G + L E + Sbjct: 31 VVVAPDRNLSGVGHSLTFTEPLKMRKIDTDFYTVIDGTPADCVHL----GYRVILEEKKP 86 Query: 146 KERIS-VAAASKILSNLVYQYKGAGLSMGTMIC 177 +S + + ++ Y +G G ++ Sbjct: 87 DLVLSGINEGPNLGEDITYSGTVSGAMEGRILG 119 >6AS7-A nrPDB Length = 922 Score = 29.6 bits (65), Expect = 1.5, Method: Composition-based stats. Identities = 24/113 (21%), Positives = 37/113 (32%), Gaps = 15/113 (13%) Query: 35 SQFQRLAPSLTVPPIASPQQFLRAHT--DDSRNPDCKIKIAHGTTTLAFRFQGGIIVAVD 92 SQF+ + +LT P P + H N K+ G T Q G + Sbjct: 796 SQFE-INKALTKDPQDYPDKKSLPHVHVALWINSQGGRKVKAGDTVSYVICQDGSNLTAS 854 Query: 93 SRATAGNWVASQT----------VKKVIEINPFLLGTMAGGAADCQFWETWLG 135 RA A + Q +++ + + + G D TWLG Sbjct: 855 QRAYAPEQLQKQDNLTIDTQYYLAQQIHPVVARICEPIDGI--DAVLIATWLG 905 >2R8U-A nrPDB Length = 268 Score = 29.6 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 11/49 (22%), Positives = 22/49 (44%), Gaps = 5/49 (10%) Query: 40 LAPSLTVPPIASPQQFLRAHTDDSRNPDCKIKIAHGTTTLAFRFQGGII 88 +APSL P + P++ L + + + P + T A + G++ Sbjct: 137 VAPSLVAPALNKPKKPLTSSSAAPQRPISTQR-----TAAAPKAGPGVV 180 >3G05-A nrPDB Length = 576 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 33/107 (30%), Gaps = 9/107 (8%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 ++ T + +F+ +V T G ++ K+ G AG Sbjct: 160 RVVGAVTQMGLKFRAKAVV-----LTVGTFLDG----KIHIGLDNYSGGRAGDPPSIPLS 210 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMIC 177 R+ L+ + A + S L Q+ + + + + Sbjct: 211 RRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMG 257 >3CP2-A nrPDB Length = 649 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 33/107 (30%), Gaps = 9/107 (8%) Query: 71 KIAHGTTTLAFRFQGGIIVAVDSRATAGNWVASQTVKKVIEINPFLLGTMAGGAADCQFW 130 ++ T + +F+ +V T G ++ K+ G AG Sbjct: 154 RVVGAVTQMGLKFRAKAVV-----LTVGTFLDG----KIHIGLDNYSGGRAGDPPSIPLS 204 Query: 131 ETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAGLSMGTMIC 177 R+ L+ + A + S L Q+ + + + + Sbjct: 205 RRLRELPLRVGRLKTGTPPRIDARTIDFSVLAQQHGDNPMPVFSFMG 251 >5US1-A nrPDB Length = 189 Score = 28.1 bits (61), Expect = 4.2, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 20/55 (36%), Gaps = 1/55 (1%) Query: 115 FLLGTMAGGAADCQFWETWLGSQCRLHELREKERISVAAASKILSNLVYQYKGAG 169 LG M A D Q + + H + ISV ++ Y+ +G G Sbjct: 51 HTLGGMHVMAFDQQKLVGHVAI-IQRHMALDNTPISVGYVEAMVVEQSYRRQGIG 104 >1YM5-A nrPDB Length = 300 Score = 27.7 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 26/77 (33%), Gaps = 10/77 (12%) Query: 171 SMGTMICGYTR----KEGPTIYYVDSDGTRLKGDIFCVGSGQTFAYGVLDSNYKW----D 222 +G ++ G + K + + GSG L YK+ D Sbjct: 192 HVGIILAGPKKEAAIKNSYEMRAFAPVINVYEDP--VCGSGSVALARYLQEVYKFEKTTD 249 Query: 223 LSVEDALYLGKRSILAA 239 +++ + L + ++ A Sbjct: 250 ITISEGGRLKRNGLMLA 266 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.139 0.348 Lambda K H 0.267 0.0425 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,935,336 Number of Sequences: 36641 Number of extensions: 428909 Number of successful extensions: 1537 Number of sequences better than 10.0: 97 Number of HSP's better than 10.0 without gapping: 140 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 1215 Number of HSP's gapped (non-prelim): 182 length of query: 287 length of database: 10,336,785 effective HSP length: 96 effective length of query: 191 effective length of database: 6,819,249 effective search space: 1302476559 effective search space used: 1302476559 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 59 (27.3 bits)