BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P30613 (574 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4IP7-A nrPDB 1096 0.0 1T5A-A nrPDB 796 0.0 6DU6-A nrPDB 607 e-174 1A3W-A nrPDB 484 e-137 4KRZ-A nrPDB 468 e-132 4KCV-B nrPDB 467 e-132 3E0V-A nrPDB 465 e-131 2E28-A nrPDB 422 e-118 3KHD-A nrPDB 397 e-111 3GG8-A nrPDB 389 e-108 3MA8-A nrPDB 381 e-106 3T0T-A nrPDB 380 e-105 1E0T-A nrPDB 379 e-105 5WSC-A nrPDB 261 7e-70 3QTG-A nrPDB 159 4e-39 1Z9C-A nrPDB 33 0.37 1VRD-A nrPDB 32 0.83 3BH4-A nrPDB 30 3.7 4FXS-A nrPDB 29 6.8 2F6U-A nrPDB 29 6.9 4FEZ-A nrPDB 29 7.2 4Z87-A nrPDB 28 9.1 >4IP7-A nrPDB Length = 543 Score = 1096 bits (2835), Expect = 0.0, Method: Compositional matrix adjust. Identities = 540/541 (99%), Positives = 540/541 (99%) Query: 34 GPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIAT 93 GPAGYLRRA VAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIAT Sbjct: 3 GPAGYLRRADVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIAT 62 Query: 94 IGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAI 153 IGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAI Sbjct: 63 IGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAI 122 Query: 154 ALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV 213 ALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV Sbjct: 123 ALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV 182 Query: 214 GGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLR 273 GGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLR Sbjct: 183 GGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLR 242 Query: 274 FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI 333 FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI Sbjct: 243 FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI 302 Query: 334 MVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVAN 393 MVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVAN Sbjct: 303 MVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVAN 362 Query: 394 AVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTE 453 AVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTE Sbjct: 363 AVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTE 422 Query: 454 VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVF 513 VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVF Sbjct: 423 VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVF 482 Query: 514 PLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573 PLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI Sbjct: 483 PLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 542 Query: 574 S 574 S Sbjct: 543 S 543 >1T5A-A nrPDB Length = 567 Score = 796 bits (2056), Expect = 0.0, Method: Compositional matrix adjust. Identities = 375/524 (71%), Positives = 444/524 (84%) Query: 50 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIK 109 E GTAF Q QQL AAMADTFLEH+C LDIDS P+ AR+T II TIGPASRSVE LKEMIK Sbjct: 43 EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIK 102 Query: 110 AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQG 169 +GMN+ARLNFSHG+HEYHAE+I NVR A ESFA P+ YRPVA+ALDTKGPEIRTG+++G Sbjct: 103 SGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKG 162 Query: 170 GPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ 229 +EVEL KG+ + +T+D A+ + + N +W+DY NI +VV VG +IY+DDGLISL V+ Sbjct: 163 SGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVK 222 Query: 230 KIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVR 289 + G + LVT+VENGG LGS+KGVNLPGA VDLP +SE+D++DL+FGVE VD+VFASF+R Sbjct: 223 QKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIR 282 Query: 290 KASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKV 349 KASDV VR LG +G IKIISKIENHEGV+RFDEILE SDGIMVARGDLGIEIPAEKV Sbjct: 283 KASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKV 342 Query: 350 FLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETA 409 FLAQKMMIGRCN AGKPV+CATQMLESMI KPRPTRAE SDVANAVLDGADCIMLSGETA Sbjct: 343 FLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETA 402 Query: 410 KGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAA 469 KG++P+EAV+MQ+ IAREAEAA+YH QLFEELRR AP++ DPTE TA+GAVEA+FKCC+ Sbjct: 403 KGDYPLEAVRMQNLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSG 462 Query: 470 AIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDV 529 AIIVLT +GRSA ++RYRPRA +IAVTR+ Q ARQ HL RG+FP+L ++P + WA+DV Sbjct: 463 AIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDV 522 Query: 530 DRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573 D RV F + GK RGF + GD+VIV+TGWRPGSG+TN MRV+ + Sbjct: 523 DLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 566 >6DU6-A nrPDB Length = 565 Score = 607 bits (1564), Expect = e-174, Method: Compositional matrix adjust. Identities = 301/506 (59%), Positives = 379/506 (74%) Query: 68 TFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYH 127 + LEH+C LDIDS+ R + II TIGPAS + E L++M+ GMNIARLNFSHGSHEYH Sbjct: 41 SHLEHMCSLDIDSQTAFVRLSGIICTIGPASVAPEMLEKMMATGMNIARLNFSHGSHEYH 100 Query: 128 AESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTV 187 A +I N+REAV++++ P+AIALDTKGPEIRTG+++G EVEL KG Q+ +T Sbjct: 101 ANTIKNIREAVDNYSKKQGKPFPLAIALDTKGPEIRTGLIEGSGTGEVELKKGEQIQLTT 160 Query: 188 DPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLG 247 D +G+ + ++VDY NIV+VV G R+++DDGLISLVV I + L VENGG+LG Sbjct: 161 DKDHLEKGSKDKIFVDYVNIVKVVKKGDRVFVDDGLISLVVDSISGDTLTCTVENGGLLG 220 Query: 248 SRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHG 307 SRKGVNLPG VDLP +SE+D DL+FGVE GVD++FASF+R A+ + +R LG +G Sbjct: 221 SRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQGVDVIFASFIRNAAALKEIRTILGEKGKN 280 Query: 308 IKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPV 367 IKIISKIEN +G++ D I+ SDGIMVARGDLGIEIPAEKVFLAQK MI RCN AGKPV Sbjct: 281 IKIISKIENQQGMQNLDAIIAASDGIMVARGDLGIEIPAEKVFLAQKSMIARCNRAGKPV 340 Query: 368 VCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIARE 427 +CATQMLESMI KPRPTRAE SDVANA++DGADC+MLSGETAKG +P+E V +E Sbjct: 341 ICATQMLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPLECVLTMAKTCKE 400 Query: 428 AEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRY 487 AEAA++HR LF +L P D AI A EAA K AAA+IV+TT+GRSA L+S+Y Sbjct: 401 AEAALWHRNLFNDLVNTTPTPLDTASSIAIAASEAAAKSRAAAVIVITTSGRSAHLISKY 460 Query: 488 RPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLR 547 RPR +IAVTR AQ ARQ HL RG+ P++Y + W DVD RVQ+G++ GK RGFL+ Sbjct: 461 RPRCPIIAVTRFAQTARQCHLYRGILPVIYEQQALEDWLKDVDARVQYGMDFGKERGFLK 520 Query: 548 VGDLVIVVTGWRPGSGYTNIMRVLSI 573 G+ V+VVTGW+ GSG+TN +R++++ Sbjct: 521 PGNPVVVVTGWKQGSGFTNTIRIVNV 546 >1A3W-A nrPDB Length = 500 Score = 484 bits (1246), Expect = e-137, Method: Compositional matrix adjust. Identities = 244/489 (49%), Positives = 329/489 (67%), Gaps = 8/489 (1%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R TSII TIGP + + E L + KAG+NI R+NFSHGS+EYH I N R++ E + G Sbjct: 19 RRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYPG-- 76 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 RP+AIALDTKGPEIRTG + + + +++ T D + + ++VDY Sbjct: 77 ---RPLAIALDTKGPEIRTGTTTN--DVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYK 131 Query: 206 NIVRVVPVGGRIYIDDGLISL-VVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGL 264 NI +V+ G IY+DDG++S V++ + + L + N G + S KGVNLPG VDLP L Sbjct: 132 NITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPAL 191 Query: 265 SEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFD 324 SE+D DLRFGV++GV +VFASF+R A+DV +R LG +G +KII KIEN +GV FD Sbjct: 192 SEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFD 251 Query: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 384 EIL+V+DG+MVARGDLGIEIPA +V QK +I + NLAGKPV+CATQMLESM PRPT Sbjct: 252 EILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPT 311 Query: 385 RAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRA 444 RAE SDV NA+LDGADC+MLSGETAKGN+P+ AV A AE A+ + ++++R Sbjct: 312 RAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNC 371 Query: 445 APLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAAR 504 P TE A AV A F+ A AIIVL+T+G + +L+S+YRP +I VTR +AAR Sbjct: 372 TPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAAR 431 Query: 505 QVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGY 564 HL RGVFP ++ + P + W DDV+ R+ FGIE K G L+ GD + + G++ G+G+ Sbjct: 432 FSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGH 491 Query: 565 TNIMRVLSI 573 +N ++V ++ Sbjct: 492 SNTLQVSTV 500 >4KRZ-A nrPDB Length = 519 Score = 468 bits (1205), Expect = e-132, Method: Compositional matrix adjust. Identities = 240/496 (48%), Positives = 324/496 (65%), Gaps = 12/496 (2%) Query: 81 EPVAA-RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVE 139 EP++ R+ I+ TIGP+++SVE LK +I++GM++AR+NFSHGSHEYH +I N+R A Sbjct: 34 EPISHHRANRIVCTIGPSTQSVEALKGLIRSGMSVARMNFSHGSHEYHQTTINNLRAAAT 93 Query: 140 SFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANT 199 + +ALDTKGPEIRTG+ + G + L G VLVT DPAF G Sbjct: 94 ELGAH------IGLALDTKGPEIRTGLFKDGG---IALAPGDTVLVTSDPAFEKIGTKEK 144 Query: 200 VWVDYPNIVRVVPVGGRIYIDDGLISL-VVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQ 258 +++YP + V GG IYIDDG++SL V+ K L V N L RKG NLPG + Sbjct: 145 FYIEYPRLSITVRPGGFIYIDDGVLSLKVLSKEDEYTLKCYVNNAHFLTDRKGCNLPGCE 204 Query: 259 VDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHE 318 VDLP +SE+D DL+FGVE G+D+VFASF+R A V VR ALG +G I IISKIENH+ Sbjct: 205 VDLPAVSEKDREDLKFGVEQGIDMVFASFIRTAEQVQEVREALGEKGKDILIISKIENHQ 264 Query: 319 GVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378 GV+ D I+E SDGIMVARGDLG+EIPAEKV +AQ ++I +CN+AGKPV+CATQMLESM Sbjct: 265 GVQNIDGIIEASDGIMVARGDLGVEIPAEKVVVAQMILISKCNVAGKPVICATQMLESMT 324 Query: 379 TKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLF 438 T PRPTRAE SDVANAV +GADC+MLSGETAKG +P E V+ I EA++A +F Sbjct: 325 TNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSATNQAVMF 384 Query: 439 EELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 498 +++ L P E AV + ++ A A++VL+ +GRSA+L S+YRP +I T Sbjct: 385 NSIKKMQKLPMSPEEAVCSSAVNSVYEVRAKALLVLSNSGRSARLASKYRPDCPIICATT 444 Query: 499 SAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGW 558 + RQ+ + R V + Y + ++ ++RVQ G++ K +G++ GDL++VV Sbjct: 445 RMRTCRQLTITRSVDAVFY-DAERYGEDENKEKRVQLGVDCAKKKGYVVPGDLMVVVHAD 503 Query: 559 RPGSGYTNIMRVLSIS 574 GY N R++ +S Sbjct: 504 HKVKGYPNQTRIIYVS 519 >4KCV-B nrPDB Length = 499 Score = 467 bits (1201), Expect = e-132, Method: Compositional matrix adjust. Identities = 247/506 (48%), Positives = 329/506 (65%), Gaps = 13/506 (2%) Query: 70 LEHLCLLDIDSEPVAA-RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHA 128 LEH L I EPVA R+ I+ TIGP+++SVE LK ++K+GM++AR+NFSHGSHEYH Sbjct: 4 LEHNIGLSI-FEPVAKHRANRIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYHQ 62 Query: 129 ESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVD 188 +I NVR A + IALDTKGPEIRTG+ + G EV G V VT D Sbjct: 63 TTINNVRAAAAELG------LHIGIALDTKGPEIRTGLFKDG---EVSFAPGDIVCVTTD 113 Query: 189 PAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISL-VVQKIGPEGLVTQVENGGVLG 247 PA+ G ++DYP + V GG IY+DDG+++L VV K L V N L Sbjct: 114 PAYEKVGTKEKFYIDYPQLTNAVRPGGSIYVDDGVMTLRVVSKEDDRTLKCHVNNHHRLT 173 Query: 248 SRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHG 307 R+G+NLPG +VDLP +SE+D +DL FGV GVD++FASF+R A V VRAALG +G Sbjct: 174 DRRGINLPGCEVDLPAVSEKDRKDLEFGVAQGVDMIFASFIRTAEQVREVRAALGEKGKD 233 Query: 308 IKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPV 367 I IISKIENH+GV+ D I+E S+GIMVARGDLG+EIPAEKV +AQ +I +CN+ GKPV Sbjct: 234 ILIISKIENHQGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKPV 293 Query: 368 VCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIARE 427 +CATQMLESM + PRPTRAE SDVANAVL+GADC+MLSGETAKG +P E V+ I E Sbjct: 294 ICATQMLESMTSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQYMARICVE 353 Query: 428 AEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRY 487 A++A + +F ++ + P E AV +AF+ A A++VL+ TGRSA+L+S+Y Sbjct: 354 AQSATHDTVMFNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISKY 413 Query: 488 RPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLR 547 RP +I VT Q RQ+++ R V + Y + ++ D ++RV+ G++ K + Sbjct: 414 RPNCPIICVTTRLQTCRQLNVTRSVVSVFY-DAAKSGEDKDKEKRVKLGLDFAKKEKYAS 472 Query: 548 VGDLVIVVTGWRPGSGYTNIMRVLSI 573 GD+V+VV GY N R++ + Sbjct: 473 TGDVVVVVHADHSVKGYPNQTRLIYL 498 >3E0V-A nrPDB Length = 539 Score = 465 bits (1197), Expect = e-131, Method: Compositional matrix adjust. Identities = 239/494 (48%), Positives = 324/494 (65%), Gaps = 14/494 (2%) Query: 81 EPVAA-RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVE 139 +PVA R+ II TIGP+++SVE LK +I++GM++AR+NFSHGSHEYH +I NVR+A Sbjct: 54 DPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYHQTTINNVRQAAA 113 Query: 140 SFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANT 199 + +AIALDTKGPEIRTG GG + + +G+ VT DPAF +G + Sbjct: 114 ELGVN------IAIALDTKGPEIRTGQFVGG---DAVMERGATCYVTTDPAFADKGTKDK 164 Query: 200 VWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPE-GLVTQVENGGVLGSRKGVNLPGAQ 258 ++DY N+ +VV G IYIDDG++ L VQ E L V N + R+GVNLPG Sbjct: 165 FYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTISDRRGVNLPGCD 224 Query: 259 VDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHE 318 VDLP +S +D DL+FGVE GVD++FASF+R A V VR ALGP+G I II KIENH+ Sbjct: 225 VDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGRDIMIICKIENHQ 284 Query: 319 GVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMI 378 GV+ D I+E SDGIMVARGDLG+EIPAEKV +AQK++I +CN+AGKPV+CATQMLESM Sbjct: 285 GVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKPVICATQMLESMT 344 Query: 379 TKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLF 438 PRPTRAE SDVANAV +GADC+MLSGETAKG +P E V+ I EA++A+ F Sbjct: 345 YNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICLEAQSALNEYVFF 404 Query: 439 EELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTR 498 +++ + E AV + ++ A A++VL+ TGRSA+L+++YRP ++ VT Sbjct: 405 NSIKKLQHIPMSADEAVCSSAVNSVYETKAKAMVVLSNTGRSARLVAKYRPNCPIVCVTT 464 Query: 499 SAQAARQVHLCRGVFPLLYR-EPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTG 557 Q RQ+++ +GV + + + W + RV G+E K +G+++ GD +V+ Sbjct: 465 RLQTCRQLNITQGVESVFFDADKLGHDWGK--EHRVAAGVEFAKSKGYVQTGDYCVVIHA 522 Query: 558 WRPGSGYTNIMRVL 571 GY N R+L Sbjct: 523 DHKVKGYANQTRIL 536 >2E28-A nrPDB Length = 587 Score = 422 bits (1086), Expect = e-118, Method: Compositional matrix adjust. Identities = 228/495 (46%), Positives = 319/495 (64%), Gaps = 28/495 (5%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R T I++TIGPAS SV++L ++++AGMN+ARLNFSHG HE H IAN+REA + Sbjct: 3 RKTKIVSTIGPASESVDKLVQLMEAGMNVARLNFSHGDHEEHGRRIANIREAAKR----- 57 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + R VAI LDTKGPEIRT ++ G +EL +GS++++++ G + V YP Sbjct: 58 -TGRTVAILLDTKGPEIRTHNMENGA---IELKEGSKLVISMSEVL---GTPEKISVTYP 110 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIGPEG--LVTQVENGGVLGSRKGVNLPGAQVDLPG 263 +++ V VG +I +DDGLISL V + + +VT V NGGVL ++KGVN+PG +V+LPG Sbjct: 111 SLIDDVSVGAKILLDDGLISLEVNAVDKQAGEIVTTVLNGGVLKNKKGVNVPGVKVNLPG 170 Query: 264 LSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHG---IKIISKIENHEGV 320 ++E+D D+ FG+ G+D + ASFVR+ASDV +R L E H I+II+KIEN EGV Sbjct: 171 ITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELL--EAHDALHIQIIAKIENEEGV 228 Query: 321 KRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITK 380 DEILE +DG+MVARGDLG+EIPAE+V L QK++I + N+ GKPV+ ATQML+SM Sbjct: 229 ANIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKSNMLGKPVITATQMLDSMQRN 288 Query: 381 PRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEE 440 PRPTRAE SDVANA+ DG D +MLSGETA G +PVEAVK H IA E A+ HR + + Sbjct: 289 PRPTRAEASDVANAIFDGTDAVMLSGETAAGQYPVEAVKTMHQIALRTEQALEHRDILSQ 348 Query: 441 LRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSA 500 R T+ A AAI+ T +G++ Q++++YRP+A +IAVT + Sbjct: 349 --RTKESQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPIIAVTSNE 406 Query: 501 QAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRP 560 +R++ L GV+ EA + D + +++ G ++ GDLV++ G Sbjct: 407 AVSRRLALVWGVY------TKEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPV 460 Query: 561 G-SGYTNIMRVLSIS 574 G +G TN+M+V IS Sbjct: 461 GETGSTNLMKVHVIS 475 >3KHD-A nrPDB Length = 520 Score = 397 bits (1020), Expect = e-111, Method: Compositional matrix adjust. Identities = 225/504 (44%), Positives = 308/504 (61%), Gaps = 24/504 (4%) Query: 75 LLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANV 134 +L+ ++ + ++ T I+ T+GPA +SVE L ++I AGM+I R NFSHGSHE H E NV Sbjct: 35 ILEPNNVNLRSKKTHIVCTLGPACKSVETLVKLIDAGMDICRFNFSHGSHEDHKEMFNNV 94 Query: 135 REAVESFAGSPLSYRP---VAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAF 191 +A E RP + + LDTKGPEIRTG L+ EV L +GS++ + D F Sbjct: 95 LKAQE--------LRPNCLLGMLLDTKGPEIRTGFLKN---KEVHLKEGSKLKLVTDYEF 143 Query: 192 RTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKG 251 G+ + Y + + V G I I DG +S V + + ++T+V N V+G RK Sbjct: 144 L--GDETCIACSYKKLPQSVKPGNIILIADGSVSCKVLETHEDHVITEVLNSAVIGERKN 201 Query: 252 VNLPGAQVDLPGLSEQDVRD-LRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKI 310 +NLP +VDLP +SE+D D L F + G + + ASF++ A DV +R LGP G IKI Sbjct: 202 MNLPNVKVDLPIISEKDKNDILNFAIPMGCNFIAASFIQSADDVRLIRNLLGPRGRHIKI 261 Query: 311 ISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCA 370 I KIEN EG+ FD+IL SDGIM+ARGDLG+EI EKVFLAQK+MI +CNL GKP++ A Sbjct: 262 IPKIENIEGIIHFDKILAESDGIMIARGDLGMEISPEKVFLAQKLMISKCNLQGKPIITA 321 Query: 371 TQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEA 430 TQMLESM PRPTRAE +DVANAVLDG DC+MLSGETA G FPVEAV + I EAEA Sbjct: 322 TQMLESMTKNPRPTRAEVTDVANAVLDGTDCVMLSGETAGGKFPVEAVTIMSKICLEAEA 381 Query: 431 AVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPR 490 + ++ L++ L A E A AVE A A+ II LT TG +A+L+++Y+P Sbjct: 382 CIDYKLLYQSLVNAIETPISVQEAVARSAVETAESIQASLIIALTETGYTARLIAKYKPS 441 Query: 491 AAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGD 550 ++A++ S + +++ RGV + + D ++ IE K R +VGD Sbjct: 442 CTILALSASDSTVKCLNVHRGVTCI------KVGSFQGTDIVIRNAIEIAKQRNMAKVGD 495 Query: 551 LVIVVTGWRPG-SGYTNIMRVLSI 573 VI + G + SG TN+M+V+ I Sbjct: 496 SVIAIHGIKEEVSGGTNLMKVVQI 519 >3GG8-A nrPDB Length = 511 Score = 389 bits (999), Expect = e-108, Method: Compositional matrix adjust. Identities = 220/498 (44%), Positives = 304/498 (61%), Gaps = 23/498 (4%) Query: 81 EPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVES 140 E A T I+ T+GPA +V+ L +MI AGMN+ RLNFSHG HE HA ++ N++EA++ Sbjct: 31 EDWTAHRTRIVCTMGPACWNVDTLVKMIDAGMNVCRLNFSHGDHETHARTVQNIQEAMKQ 90 Query: 141 FAGSPLSYRP---VAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNA 197 RP +AI LDTKGPEIRTG L+ + L +G+ + + D + G+ Sbjct: 91 --------RPEARLAILLDTKGPEIRTGFLKD--HKPITLQQGATLKIVTD--YNLIGDE 138 Query: 198 NTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGA 257 T+ Y + + V G I I DG +S+ V ++G + ++TQ +N +G RK +NLP Sbjct: 139 TTIACSYGALPQSVKPGNTILIADGSLSVKVVEVGSDYVITQAQNTATIGERKNMNLPNV 198 Query: 258 QVDLPGLSEQDVRD-LRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIEN 316 +V LP + E+D D L FG+ G + + ASFV+ A DV +R LGP G I+II KIEN Sbjct: 199 KVQLPVIGEKDKHDILNFGIPMGCNFIAASFVQSADDVRYIRGLLGPRGRHIRIIPKIEN 258 Query: 317 HEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLES 376 EG+ FDEIL +DGIM+ARGDLG+EIP EKVFLAQKMMI +CN+ GKPV+ ATQMLES Sbjct: 259 VEGLVNFDEILAEADGIMIARGDLGMEIPPEKVFLAQKMMIAKCNVVGKPVITATQMLES 318 Query: 377 MITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQ 436 MI PRPTRAE +DVANAVLDG DC+MLSGETA G FPV V+ I EAE V + Sbjct: 319 MIKNPRPTRAEAADVANAVLDGTDCVMLSGETANGEFPVITVETMARICYEAETCVDYPA 378 Query: 437 LFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAV 496 L+ + A P E A AVE A AA I+ LT TG++A+L+++YRP ++A+ Sbjct: 379 LYRAMCLAVPPPISTQEAVARAAVETAECVNAAIILALTETGQTARLIAKYRPMQPILAL 438 Query: 497 TRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVT 556 + S + + + RGV + + P D V R I K R + G+ ++ V Sbjct: 439 SASESTIKHLQVIRGVTTM---QVPSFQGTDHVIRN---AIVVAKERELVTEGESIVAVH 492 Query: 557 GWRPG-SGYTNIMRVLSI 573 G + +G +N+++VL++ Sbjct: 493 GMKEEVAGSSNLLKVLTV 510 >3MA8-A nrPDB Length = 534 Score = 381 bits (978), Expect = e-106, Method: Compositional matrix adjust. Identities = 220/532 (41%), Positives = 307/532 (57%), Gaps = 30/532 (5%) Query: 55 FFQQQQLPAAMADTFLEHLCL-LDIDSEPVA-----ARSTSIIATIGPASRSVERLKEMI 108 +FQ A M+ T + CL +D P+A R T II TIGP+ +VE L +I Sbjct: 15 YFQGASTSAVMSCTLGKATCLGMDKICSPLADNDVTQRKTQIICTIGPSCNNVESLIGLI 74 Query: 109 KAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQ 168 GM++ARLNFSHG HE H +++ N+REA ++ + V I LDTKGPEIRTG+L+ Sbjct: 75 DKGMSVARLNFSHGDHESHFKTLQNIREAAKARP-----HSTVGIMLDTKGPEIRTGMLE 129 Query: 169 GGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVV 228 GG +EL G + +T D + GN+ + Y + + V +G + I DG +S V Sbjct: 130 GG--KPIELKAGQTLKITTD--YSMLGNSECISCSYSLLPKSVQIGSTVLIADGSLSTQV 185 Query: 229 QKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDL-RFGVEHGVDIVFASF 287 +IG + +V +V N +G RK +NLPG +V LP + ++D D+ F +++ +D + SF Sbjct: 186 LEIGDDFIVCKVLNSVTIGERKNMNLPGCKVHLPIIGDKDRHDIVDFALKYNLDFIALSF 245 Query: 288 VRKASDVAAVRAALGPEGH-------GIKIISKIENHEGVKRFDEILEVSDGIMVARGDL 340 V+ +DV R + IKIISKIEN EGV FD I SDGIMVARGDL Sbjct: 246 VQNGADVQLCRQIISENTQYSNGIPSSIKIISKIENLEGVINFDSICSESDGIMVARGDL 305 Query: 341 GIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGAD 400 G+EIP EK+F+AQK MI +CN+AGKPVV ATQMLESMI RPTRAE +DVANAVLDG+D Sbjct: 306 GMEIPPEKIFVAQKCMISKCNVAGKPVVTATQMLESMIKSNRPTRAEMTDVANAVLDGSD 365 Query: 401 CIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAV 460 C+MLSGETA G FP +AV + + +AE + + L+ + + P E A AV Sbjct: 366 CVMLSGETANGAFPFDAVNVMSRVCAQAETCIDYPVLYHAIHSSVPKPVAVPEAIACSAV 425 Query: 461 EAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREP 520 E+A A II +T TG +A+L+S+YRP +IA T + AR + + RGV + Sbjct: 426 ESAHDVNAKLIITITETGNTARLISKYRPSQTIIACTAKPEVARGLKIARGVKTYVLN-- 483 Query: 521 PEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGS-GYTNIMRVL 571 +I +V + + K + GD I V G + G N+M+++ Sbjct: 484 --SIHHSEV--VISNALALAKEESLIESGDFAIAVHGVKESCPGSCNLMKIV 531 >3T0T-A nrPDB Length = 606 Score = 380 bits (975), Expect = e-105, Method: Compositional matrix adjust. Identities = 217/492 (44%), Positives = 303/492 (61%), Gaps = 31/492 (6%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R T I+ TIGPAS S E ++++I AGMN+ARLNFSHGSHE H I +R+ + Sbjct: 23 RKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLD--- 79 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + VAI LDTKGPEIRT ++ G +EL +G++V+V+++ G V Y Sbjct: 80 ---KIVAILLDTKGPEIRTHNMKDGI---IELERGNEVIVSMN---EVEGTPEKFSVTYE 130 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKI--GPEGLVTQVENGGVLGSRKGVNLPGAQVDLPG 263 N++ V VG I +DDGLI L V+ I + + + N G L ++KGVNLPG +V LPG Sbjct: 131 NLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPG 190 Query: 264 LSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRF 323 ++E+D D+RFG++ VD + ASFVR+ SDV +R L + I + KIEN EG+ Sbjct: 191 ITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNI 250 Query: 324 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 383 +EILEVSDG+MVARGD+G+EIP EKV + QK +I +CN GKPV+ ATQML+SM PR Sbjct: 251 EEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRA 310 Query: 384 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRR 443 TRAE SDVANA+ DG D +MLSGETA G +P EAVK IA AEAA +++L + + Sbjct: 311 TRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTK 370 Query: 444 AAPLSRDPTEVTAIG--AVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQ 501 S V AIG A AI+ T +G +A+ +S+YRP + +IAVT S + Sbjct: 371 LVETSL----VNAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEE 426 Query: 502 AARQVHLCRGVFPLLY--REPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWR 559 ARQ + GV P++ R+ +A+ ++ V +E+G++ GDL+I+ G Sbjct: 427 TARQCSIVWGVQPVVKKGRKSTDAL----LNNAVATAVETGRVTN----GDLIIITAGVP 478 Query: 560 PG-SGYTNIMRV 570 G +G TN+M++ Sbjct: 479 TGETGTTNMMKI 490 >1E0T-A nrPDB Length = 470 Score = 379 bits (974), Expect = e-105, Method: Compositional matrix adjust. Identities = 221/486 (45%), Positives = 283/486 (58%), Gaps = 21/486 (4%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 + T I+ TIGP + S E L +M+ AGMN+ RLNFSHG + H + I N+R + Sbjct: 2 KKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSK----- 56 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + + AI LDTKGPEIRT L+GG ++V L G T D + GN+ V V Y Sbjct: 57 -TGKTAAILLDTKGPEIRTMKLEGG--NDVSLKAGQTFTFTTDKSVI--GNSEMVAVTYE 111 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLS 265 + VG + +DDGLI + V I ++ +V N G LG KGVNLPG + LP L+ Sbjct: 112 GFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALA 171 Query: 266 EQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEG-HGIKIISKIENHEGVKRFD 324 E+D +DL FG E GVD V ASF+RK SDV +R L G I IISKIEN EG+ FD Sbjct: 172 EKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFD 231 Query: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 384 EILE SDGIMVARGDLG+EIP E+V AQKMMI +C A K V+ AT ML+SMI PRPT Sbjct: 232 EILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATMMLDSMIKNPRPT 291 Query: 385 RAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRA 444 AE DVANA+LDG D +MLSGE+AKG +P+EAV + I + + R F R Sbjct: 292 DAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRK 351 Query: 445 APLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAAR 504 + TE GAVE A K A I+V T G+SA+ + +Y P A ++A+T + + A Sbjct: 352 LRI----TEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAH 407 Query: 505 QVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGY 564 Q+ L +GV P L + E DD R G E G GD+V++V+G SG Sbjct: 408 QLVLSKGVVPQLVK---EITSTDDFYR---LGKELALQSGLAHKGDVVVMVSGALVPSGT 461 Query: 565 TNIMRV 570 TN V Sbjct: 462 TNTASV 467 >5WSC-A nrPDB Length = 475 Score = 261 bits (666), Expect = 7e-70, Method: Compositional matrix adjust. Identities = 175/492 (35%), Positives = 261/492 (53%), Gaps = 31/492 (6%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R I+ T+GPA++ + ++ +++AGM++AR+NFSHG ++ H + VR A S Sbjct: 6 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVA------SD 59 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + R V + D +GP+IR G G E G V +TV G+ + V Y Sbjct: 60 ATGRAVGVLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 113 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLS 265 + + G R+ +DDG ++LVV + + +V V GG + KG++LPG V P LS Sbjct: 114 RLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALS 173 Query: 266 EQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDE 325 E+D+ DL F + GVD+V SFVR +DV V + G + +I+K+E E + + Sbjct: 174 EKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEA 233 Query: 326 ILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTR 385 I+ D +MVARGDLG+E+P E+V L QK I KPV+ ATQML+SMI RPTR Sbjct: 234 IVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTR 293 Query: 386 AETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAA 445 AE SDVANAVLDGAD +MLSGET+ G +P+ AV+ I E E A Sbjct: 294 AEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVE---------ENSTAAP 344 Query: 446 PLSRDPTE---VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQA 502 PL+ P V + A + + A A++ T +G + + L+R ++A T + Sbjct: 345 PLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEV 404 Query: 503 ARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGS 562 Q+ + G + P+ D + R+V + +L + R GDLV++V G PG+ Sbjct: 405 RSQLAMTWGTETFIV---PKMQSTDGMIRQVDKSLL--ELARYKR-GDLVVIVAGAPPGT 458 Query: 563 -GYTNIMRVLSI 573 G TN++ V I Sbjct: 459 VGSTNLIHVHRI 470 >3QTG-A nrPDB Length = 461 Score = 159 bits (401), Expect = 4e-39, Method: Compositional matrix adjust. Identities = 128/434 (29%), Positives = 206/434 (47%), Gaps = 35/434 (8%) Query: 88 TSIIATIGPASRSVERLKEMIK--AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 T +AT+GP S V R E+IK ++ R+N +H S I EAV S+ + Sbjct: 17 TKRVATLGP-STDVLRPDELIKFLDLVDGVRINLAHASPNEVKFRI----EAVRSYEKA- 70 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 RP+A+ +D KGP IR G E E+VK F+ ++ ++ P Sbjct: 71 -KNRPLAVIVDLKGPSIRVGSTSPINVQEGEVVK-----------FKLSDKSDGTYIPVP 118 Query: 206 N--IVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPG 263 N V I + DG + L V G + + E+ GV+ K + + G D+ Sbjct: 119 NKAFFSAVEQNDVILMLDGRLRLKVTNTGSDWIEAVAESSGVITGGKAIVVEGKDYDIST 178 Query: 264 LSEQDVRDLR--FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVK 321 +E+DV L+ + +D V S + DV +VR+ L G ++ KIE V Sbjct: 179 PAEEDVEALKAISPIRDNIDYVAISLAKSCKDVDSVRSLLTELGFQSQVAVKIETKGAVN 238 Query: 322 RFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKP 381 +E+++ SD ++VARGDLG+ + + + Q+ ++ GKP+ ATQ+L+SM + P Sbjct: 239 NLEELVQCSDYVVVARGDLGLHYGLDALPIVQRRIVHTSLKYGKPIAVATQLLDSMQSSP 298 Query: 382 RPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 441 PTRAE +DV G D + L+ ETA G +P+ AV I E + Sbjct: 299 IPTRAEINDVFTTASMGVDSLWLTNETASGKYPLAAVSWLSRILMNVEYQIPQ------- 351 Query: 442 RRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQ 501 +PL ++ + A G VE A + A I+V + +G A+ ++++RPR V T + + Sbjct: 352 ---SPLLQNSRDRFAKGLVELA-QDLGANILVFSMSGTLARRIAKFRPRGVVYVGTPNVR 407 Query: 502 AARQVHLCRGVFPL 515 AR + + + PL Sbjct: 408 VARSLSIVWALEPL 421 >1Z9C-A nrPDB Length = 147 Score = 33.1 bits (74), Expect = 0.37, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 42/78 (53%), Gaps = 15/78 (19%) Query: 210 VVPVGGRIYIDDGLISLVVQKIGPEGLVTQ--------------VENGGVLGSRKGVNLP 255 V +G ++Y+D G ++ +++++ +GL+T+ E+G +L K V++P Sbjct: 57 VKKMGEQLYLDSGTLTPMLKRMEQQGLITRKRSEEDERSVLISLTEDGALL-KEKAVDIP 115 Query: 256 GAQVDLPGLSEQDVRDLR 273 G + L S +D++ L+ Sbjct: 116 GTILGLSKQSGEDLKQLK 133 >1VRD-A nrPDB Length = 494 Score = 32.0 bits (71), Expect = 0.83, Method: Compositional matrix adjust. Identities = 19/85 (22%), Positives = 44/85 (51%), Gaps = 8/85 (9%) Query: 59 QQLPAAMADTFLEHLC----LLDIDSEPVAARSTS----IIATIGPASRSVERLKEMIKA 110 ++LP D L L ++ + P AAR + A +G + ++ER+++++KA Sbjct: 189 EKLPLVSKDNKLVGLITIKDIMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKA 248 Query: 111 GMNIARLNFSHGSHEYHAESIANVR 135 G+++ ++ +HG E++ ++ Sbjct: 249 GVDVIVIDTAHGHSRRVIETLEMIK 273 >3BH4-A nrPDB Length = 483 Score = 29.6 bits (65), Expect = 3.7, Method: Compositional matrix adjust. Identities = 40/150 (26%), Positives = 61/150 (40%), Gaps = 39/150 (26%) Query: 89 SIIATIGPASRSVERLKEMIKAGMNIARLNFSHG-SHEY--HAESIANVREAVESFAGSP 145 + T G + + + LK+ I+ + AR +++G H+Y H + I RE S A S Sbjct: 365 DMYGTKGTSPKEIPSLKDNIEPILK-ARKEYAYGPQHDYIDHPDVIGWTREGDSSAAKSG 423 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 L+ AL T GP GG + +K NA W D Sbjct: 424 LA------ALITDGP--------GGSKRMYAGLK----------------NAGETWYDIT 453 Query: 206 -NIVRVVPVG----GRIYIDDGLISLVVQK 230 N V +G G +++DG +S+ VQK Sbjct: 454 GNRSDTVKIGSDGWGEFHVNDGSVSIYVQK 483 >4FXS-A nrPDB Length = 496 Score = 28.9 bits (63), Expect = 6.8, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 27/46 (58%) Query: 92 ATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREA 137 A +G A + ER+K +++AG+++ ++ SHG E + I R A Sbjct: 224 AAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAA 269 >2F6U-A nrPDB Length = 234 Score = 28.9 bits (63), Expect = 6.9, Method: Compositional matrix adjust. Identities = 14/30 (46%), Positives = 18/30 (60%), Gaps = 1/30 (3%) Query: 378 ITKPRPTRAETSDVANAVLD-GADCIMLSG 406 ITK P R T ++ AV D G D +M+SG Sbjct: 12 ITKLDPDRTNTDEIIKAVADSGTDAVMISG 41 >4FEZ-A nrPDB Length = 388 Score = 28.9 bits (63), Expect = 7.2, Method: Compositional matrix adjust. Identities = 15/46 (32%), Positives = 27/46 (58%) Query: 92 ATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREA 137 A +G A + ER+K +++AG+++ ++ SHG E + I R A Sbjct: 123 AAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSEGVLQRIRETRAA 168 >4Z87-A nrPDB Length = 525 Score = 28.5 bits (62), Expect = 9.1, Method: Compositional matrix adjust. Identities = 24/110 (21%), Positives = 49/110 (44%), Gaps = 8/110 (7%) Query: 68 TFLEHLCLLDIDSEPVAARSTSII-----ATIGPASRSVERLKEMIKAGMNIARLNFSHG 122 + L L+ S P+A++S A IG +RL +++AG+++ L+ S G Sbjct: 225 SMLSRTDLMKNQSYPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQG 284 Query: 123 SHEYHAESIANVREA---VESFAGSPLSYRPVAIALDTKGPEIRTGILQG 169 + + I ++E ++ AG+ ++ A + +R G+ G Sbjct: 285 NSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSG 334 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4IP7-A nrPDB 848 0.0 1T5A-A nrPDB 803 0.0 6DU6-A nrPDB 738 0.0 4KRZ-A nrPDB 706 0.0 3E0V-A nrPDB 700 0.0 4KCV-B nrPDB 697 0.0 1A3W-A nrPDB 662 0.0 3MA8-A nrPDB 658 0.0 3KHD-A nrPDB 657 0.0 3GG8-A nrPDB 644 0.0 1E0T-A nrPDB 601 e-172 2E28-A nrPDB 598 e-171 3T0T-A nrPDB 597 e-171 5WSC-A nrPDB 547 e-156 3QTG-A nrPDB 450 e-127 Sequences not found previously or not previously below threshold: 1DXF-A nrPDB 44 2e-04 3QLL-A nrPDB 39 0.004 4FEZ-A nrPDB 38 0.015 4FXS-A nrPDB 37 0.020 3IV8-A nrPDB 35 0.082 2YNM-D nrPDB 34 0.18 2YCL-A nrPDB 33 0.36 2VWT-A nrPDB 33 0.40 1VRD-A nrPDB 32 0.73 4L80-A nrPDB 31 1.2 1F0N-A nrPDB 30 2.3 3M6A-A nrPDB 30 3.3 4Z87-A nrPDB 30 3.4 2D2A-A nrPDB 30 3.8 5VMS-A nrPDB 29 4.9 >4IP7-A nrPDB Length = 543 Score = 848 bits (2191), Expect = 0.0, Method: Composition-based stats. Identities = 540/541 (99%), Positives = 540/541 (99%) Query: 34 GPAGYLRRASVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIAT 93 GPAGYLRRA VAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIAT Sbjct: 3 GPAGYLRRADVAQLTQELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIAT 62 Query: 94 IGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAI 153 IGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAI Sbjct: 63 IGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAI 122 Query: 154 ALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV 213 ALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV Sbjct: 123 ALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV 182 Query: 214 GGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLR 273 GGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLR Sbjct: 183 GGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLR 242 Query: 274 FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI 333 FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI Sbjct: 243 FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGI 302 Query: 334 MVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVAN 393 MVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVAN Sbjct: 303 MVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVAN 362 Query: 394 AVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTE 453 AVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTE Sbjct: 363 AVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTE 422 Query: 454 VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVF 513 VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVF Sbjct: 423 VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVF 482 Query: 514 PLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573 PLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI Sbjct: 483 PLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 542 Query: 574 S 574 S Sbjct: 543 S 543 >1T5A-A nrPDB Length = 567 Score = 803 bits (2075), Expect = 0.0, Method: Composition-based stats. Identities = 375/524 (71%), Positives = 444/524 (84%) Query: 50 ELGTAFFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIK 109 E GTAF Q QQL AAMADTFLEH+C LDIDS P+ AR+T II TIGPASRSVE LKEMIK Sbjct: 43 EAGTAFIQTQQLHAAMADTFLEHMCRLDIDSPPITARNTGIICTIGPASRSVETLKEMIK 102 Query: 110 AGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQG 169 +GMN+ARLNFSHG+HEYHAE+I NVR A ESFA P+ YRPVA+ALDTKGPEIRTG+++G Sbjct: 103 SGMNVARLNFSHGTHEYHAETIKNVRTATESFASDPILYRPVAVALDTKGPEIRTGLIKG 162 Query: 170 GPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQ 229 +EVEL KG+ + +T+D A+ + + N +W+DY NI +VV VG +IY+DDGLISL V+ Sbjct: 163 SGTAEVELKKGATLKITLDNAYMEKCDENILWLDYKNICKVVEVGSKIYVDDGLISLQVK 222 Query: 230 KIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVR 289 + G + LVT+VENGG LGS+KGVNLPGA VDLP +SE+D++DL+FGVE VD+VFASF+R Sbjct: 223 QKGADFLVTEVENGGSLGSKKGVNLPGAAVDLPAVSEKDIQDLKFGVEQDVDMVFASFIR 282 Query: 290 KASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKV 349 KASDV VR LG +G IKIISKIENHEGV+RFDEILE SDGIMVARGDLGIEIPAEKV Sbjct: 283 KASDVHEVRKVLGEKGKNIKIISKIENHEGVRRFDEILEASDGIMVARGDLGIEIPAEKV 342 Query: 350 FLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETA 409 FLAQKMMIGRCN AGKPV+CATQMLESMI KPRPTRAE SDVANAVLDGADCIMLSGETA Sbjct: 343 FLAQKMMIGRCNRAGKPVICATQMLESMIKKPRPTRAEGSDVANAVLDGADCIMLSGETA 402 Query: 410 KGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAA 469 KG++P+EAV+MQ+ IAREAEAA+YH QLFEELRR AP++ DPTE TA+GAVEA+FKCC+ Sbjct: 403 KGDYPLEAVRMQNLIAREAEAAIYHLQLFEELRRLAPITSDPTEATAVGAVEASFKCCSG 462 Query: 470 AIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDV 529 AIIVLT +GRSA ++RYRPRA +IAVTR+ Q ARQ HL RG+FP+L ++P + WA+DV Sbjct: 463 AIIVLTKSGRSAHQVARYRPRAPIIAVTRNPQTARQAHLYRGIFPVLCKDPVQEAWAEDV 522 Query: 530 DRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGYTNIMRVLSI 573 D RV F + GK RGF + GD+VIV+TGWRPGSG+TN MRV+ + Sbjct: 523 DLRVNFAMNVGKARGFFKKGDVVIVLTGWRPGSGFTNTMRVVPV 566 >6DU6-A nrPDB Length = 565 Score = 738 bits (1906), Expect = 0.0, Method: Composition-based stats. Identities = 301/508 (59%), Positives = 380/508 (74%) Query: 66 ADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHE 125 + + LEH+C LDIDS+ R + II TIGPAS + E L++M+ GMNIARLNFSHGSHE Sbjct: 39 SVSHLEHMCSLDIDSQTAFVRLSGIICTIGPASVAPEMLEKMMATGMNIARLNFSHGSHE 98 Query: 126 YHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLV 185 YHA +I N+REAV++++ P+AIALDTKGPEIRTG+++G EVEL KG Q+ + Sbjct: 99 YHANTIKNIREAVDNYSKKQGKPFPLAIALDTKGPEIRTGLIEGSGTGEVELKKGEQIQL 158 Query: 186 TVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGV 245 T D +G+ + ++VDY NIV+VV G R+++DDGLISLVV I + L VENGG+ Sbjct: 159 TTDKDHLEKGSKDKIFVDYVNIVKVVKKGDRVFVDDGLISLVVDSISGDTLTCTVENGGL 218 Query: 246 LGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEG 305 LGSRKGVNLPG VDLP +SE+D DL+FGVE GVD++FASF+R A+ + +R LG +G Sbjct: 219 LGSRKGVNLPGVPVDLPAVSEKDKSDLQFGVEQGVDVIFASFIRNAAALKEIRTILGEKG 278 Query: 306 HGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGK 365 IKIISKIEN +G++ D I+ SDGIMVARGDLGIEIPAEKVFLAQK MI RCN AGK Sbjct: 279 KNIKIISKIENQQGMQNLDAIIAASDGIMVARGDLGIEIPAEKVFLAQKSMIARCNRAGK 338 Query: 366 PVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIA 425 PV+CATQMLESMI KPRPTRAE SDVANA++DGADC+MLSGETAKG +P+E V Sbjct: 339 PVICATQMLESMIKKPRPTRAEISDVANAIIDGADCVMLSGETAKGEYPLECVLTMAKTC 398 Query: 426 REAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLS 485 +EAEAA++HR LF +L P D AI A EAA K AAA+IV+TT+GRSA L+S Sbjct: 399 KEAEAALWHRNLFNDLVNTTPTPLDTASSIAIAASEAAAKSRAAAVIVITTSGRSAHLIS 458 Query: 486 RYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGF 545 +YRPR +IAVTR AQ ARQ HL RG+ P++Y + W DVD RVQ+G++ GK RGF Sbjct: 459 KYRPRCPIIAVTRFAQTARQCHLYRGILPVIYEQQALEDWLKDVDARVQYGMDFGKERGF 518 Query: 546 LRVGDLVIVVTGWRPGSGYTNIMRVLSI 573 L+ G+ V+VVTGW+ GSG+TN +R++++ Sbjct: 519 LKPGNPVVVVTGWKQGSGFTNTIRIVNV 546 >4KRZ-A nrPDB Length = 519 Score = 706 bits (1821), Expect = 0.0, Method: Composition-based stats. Identities = 244/509 (47%), Positives = 328/509 (64%), Gaps = 13/509 (2%) Query: 68 TFLEHLCLLDIDSEPVAA-RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEY 126 + L H L I EP++ R+ I+ TIGP+++SVE LK +I++GM++AR+NFSHGSHEY Sbjct: 22 SQLAHNVNLSI-FEPISHHRANRIVCTIGPSTQSVEALKGLIRSGMSVARMNFSHGSHEY 80 Query: 127 HAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVT 186 H +I N+R A + +ALDTKGPEIRTG+ + G + L G VLVT Sbjct: 81 HQTTINNLRAAATELGAH------IGLALDTKGPEIRTGLFKDGG---IALAPGDTVLVT 131 Query: 187 VDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPE-GLVTQVENGGV 245 DPAF G +++YP + V GG IYIDDG++SL V E L V N Sbjct: 132 SDPAFEKIGTKEKFYIEYPRLSITVRPGGFIYIDDGVLSLKVLSKEDEYTLKCYVNNAHF 191 Query: 246 LGSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEG 305 L RKG NLPG +VDLP +SE+D DL+FGVE G+D+VFASF+R A V VR ALG +G Sbjct: 192 LTDRKGCNLPGCEVDLPAVSEKDREDLKFGVEQGIDMVFASFIRTAEQVQEVREALGEKG 251 Query: 306 HGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGK 365 I IISKIENH+GV+ D I+E SDGIMVARGDLG+EIPAEKV +AQ ++I +CN+AGK Sbjct: 252 KDILIISKIENHQGVQNIDGIIEASDGIMVARGDLGVEIPAEKVVVAQMILISKCNVAGK 311 Query: 366 PVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIA 425 PV+CATQMLESM T PRPTRAE SDVANAV +GADC+MLSGETAKG +P E V+ I Sbjct: 312 PVICATQMLESMTTNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARIC 371 Query: 426 REAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLS 485 EA++A +F +++ L P E AV + ++ A A++VL+ +GRSA+L S Sbjct: 372 LEAQSATNQAVMFNSIKKMQKLPMSPEEAVCSSAVNSVYEVRAKALLVLSNSGRSARLAS 431 Query: 486 RYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGF 545 +YRP +I T + RQ+ + R V + Y + ++ ++RVQ G++ K +G+ Sbjct: 432 KYRPDCPIICATTRMRTCRQLTITRSVDAVFY-DAERYGEDENKEKRVQLGVDCAKKKGY 490 Query: 546 LRVGDLVIVVTGWRPGSGYTNIMRVLSIS 574 + GDL++VV GY N R++ +S Sbjct: 491 VVPGDLMVVVHADHKVKGYPNQTRIIYVS 519 >3E0V-A nrPDB Length = 539 Score = 700 bits (1806), Expect = 0.0, Method: Composition-based stats. Identities = 239/507 (47%), Positives = 326/507 (64%), Gaps = 11/507 (2%) Query: 68 TFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYH 127 + L H L I R+ II TIGP+++SVE LK +I++GM++AR+NFSHGSHEYH Sbjct: 42 SQLAHNLTLSIFDPVANYRAARIICTIGPSTQSVEALKGLIQSGMSVARMNFSHGSHEYH 101 Query: 128 AESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTV 187 +I NVR+A + +AIALDTKGPEIRTG GG + + +G+ VT Sbjct: 102 QTTINNVRQAAAELGVN------IAIALDTKGPEIRTGQFVGG---DAVMERGATCYVTT 152 Query: 188 DPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPE-GLVTQVENGGVL 246 DPAF +G + ++DY N+ +VV G IYIDDG++ L VQ E L V N + Sbjct: 153 DPAFADKGTKDKFYIDYQNLSKVVRPGNYIYIDDGILILQVQSHEDEQTLECTVTNSHTI 212 Query: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306 R+GVNLPG VDLP +S +D DL+FGVE GVD++FASF+R A V VR ALGP+G Sbjct: 213 SDRRGVNLPGCDVDLPAVSAKDRVDLQFGVEQGVDMIFASFIRSAEQVGDVRKALGPKGR 272 Query: 307 GIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKP 366 I II KIENH+GV+ D I+E SDGIMVARGDLG+EIPAEKV +AQK++I +CN+AGKP Sbjct: 273 DIMIICKIENHQGVQNIDSIIEESDGIMVARGDLGVEIPAEKVVVAQKILISKCNVAGKP 332 Query: 367 VVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAR 426 V+CATQMLESM PRPTRAE SDVANAV +GADC+MLSGETAKG +P E V+ I Sbjct: 333 VICATQMLESMTYNPRPTRAEVSDVANAVFNGADCVMLSGETAKGKYPNEVVQYMARICL 392 Query: 427 EAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSR 486 EA++A+ F +++ + E AV + ++ A A++VL+ TGRSA+L+++ Sbjct: 393 EAQSALNEYVFFNSIKKLQHIPMSADEAVCSSAVNSVYETKAKAMVVLSNTGRSARLVAK 452 Query: 487 YRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFL 546 YRP ++ VT Q RQ+++ +GV + + + + + RV G+E K +G++ Sbjct: 453 YRPNCPIVCVTTRLQTCRQLNITQGVESVFF-DADKLGHDWGKEHRVAAGVEFAKSKGYV 511 Query: 547 RVGDLVIVVTGWRPGSGYTNIMRVLSI 573 + GD +V+ GY N R+L + Sbjct: 512 QTGDYCVVIHADHKVKGYANQTRILLV 538 >4KCV-B nrPDB Length = 499 Score = 697 bits (1800), Expect = 0.0, Method: Composition-based stats. Identities = 243/507 (47%), Positives = 326/507 (64%), Gaps = 11/507 (2%) Query: 68 TFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYH 127 + LEH L I R+ I+ TIGP+++SVE LK ++K+GM++AR+NFSHGSHEYH Sbjct: 2 SQLEHNIGLSIFEPVAKHRANRIVCTIGPSTQSVEALKNLMKSGMSVARMNFSHGSHEYH 61 Query: 128 AESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTV 187 +I NVR A + IALDTKGPEIRTG+ + G EV G V VT Sbjct: 62 QTTINNVRAAAAEL------GLHIGIALDTKGPEIRTGLFKDG---EVSFAPGDIVCVTT 112 Query: 188 DPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISL-VVQKIGPEGLVTQVENGGVL 246 DPA+ G ++DYP + V GG IY+DDG+++L VV K L V N L Sbjct: 113 DPAYEKVGTKEKFYIDYPQLTNAVRPGGSIYVDDGVMTLRVVSKEDDRTLKCHVNNHHRL 172 Query: 247 GSRKGVNLPGAQVDLPGLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGH 306 R+G+NLPG +VDLP +SE+D +DL FGV GVD++FASF+R A V VRAALG +G Sbjct: 173 TDRRGINLPGCEVDLPAVSEKDRKDLEFGVAQGVDMIFASFIRTAEQVREVRAALGEKGK 232 Query: 307 GIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKP 366 I IISKIENH+GV+ D I+E S+GIMVARGDLG+EIPAEKV +AQ +I +CN+ GKP Sbjct: 233 DILIISKIENHQGVQNIDSIIEASNGIMVARGDLGVEIPAEKVCVAQMCIISKCNVVGKP 292 Query: 367 VVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAR 426 V+CATQMLESM + PRPTRAE SDVANAVL+GADC+MLSGETAKG +P E V+ I Sbjct: 293 VICATQMLESMTSNPRPTRAEVSDVANAVLNGADCVMLSGETAKGKYPNEVVQYMARICV 352 Query: 427 EAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSR 486 EA++A + +F ++ + P E AV +AF+ A A++VL+ TGRSA+L+S+ Sbjct: 353 EAQSATHDTVMFNSIKNLQKIPMCPEEAVCSSAVASAFEVQAKAMLVLSNTGRSARLISK 412 Query: 487 YRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFL 546 YRP +I VT Q RQ+++ R V + Y + ++ D ++RV+ G++ K + Sbjct: 413 YRPNCPIICVTTRLQTCRQLNVTRSVVSVFY-DAAKSGEDKDKEKRVKLGLDFAKKEKYA 471 Query: 547 RVGDLVIVVTGWRPGSGYTNIMRVLSI 573 GD+V+VV GY N R++ + Sbjct: 472 STGDVVVVVHADHSVKGYPNQTRLIYL 498 >1A3W-A nrPDB Length = 500 Score = 662 bits (1707), Expect = 0.0, Method: Composition-based stats. Identities = 243/489 (49%), Positives = 327/489 (66%), Gaps = 8/489 (1%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R TSII TIGP + + E L + KAG+NI R+NFSHGS+EYH I N R++ E + Sbjct: 19 RRTSIIGTIGPKTNNPETLVALRKAGLNIVRMNFSHGSYEYHKSVIDNARKSEELYP--- 75 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 RP+AIALDTKGPEIRTG + + + +++ T D + + ++VDY Sbjct: 76 --GRPLAIALDTKGPEIRTGTTTN--DVDYPIPPNHEMIFTTDDKYAKACDDKIMYVDYK 131 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKI-GPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGL 264 NI +V+ G IY+DDG++S V ++ + L + N G + S KGVNLPG VDLP L Sbjct: 132 NITKVISAGRIIYVDDGVLSFQVLEVVDDKTLKVKALNAGKICSHKGVNLPGTDVDLPAL 191 Query: 265 SEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFD 324 SE+D DLRFGV++GV +VFASF+R A+DV +R LG +G +KII KIEN +GV FD Sbjct: 192 SEKDKEDLRFGVKNGVHMVFASFIRTANDVLTIREVLGEQGKDVKIIVKIENQQGVNNFD 251 Query: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 384 EIL+V+DG+MVARGDLGIEIPA +V QK +I + NLAGKPV+CATQMLESM PRPT Sbjct: 252 EILKVTDGVMVARGDLGIEIPAPEVLAVQKKLIAKSNLAGKPVICATQMLESMTYNPRPT 311 Query: 385 RAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRA 444 RAE SDV NA+LDGADC+MLSGETAKGN+P+ AV A AE A+ + ++++R Sbjct: 312 RAEVSDVGNAILDGADCVMLSGETAKGNYPINAVTTMAETAVIAEQAIAYLPNYDDMRNC 371 Query: 445 APLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAAR 504 P TE A AV A F+ A AIIVL+T+G + +L+S+YRP +I VTR +AAR Sbjct: 372 TPKPTSTTETVAASAVAAVFEQKAKAIIVLSTSGTTPRLVSKYRPNCPIILVTRCPRAAR 431 Query: 505 QVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGY 564 HL RGVFP ++ + P + W DDV+ R+ FGIE K G L+ GD + + G++ G+G+ Sbjct: 432 FSHLYRGVFPFVFEKEPVSDWTDDVEARINFGIEKAKEFGILKKGDTYVSIQGFKAGAGH 491 Query: 565 TNIMRVLSI 573 +N ++V ++ Sbjct: 492 SNTLQVSTV 500 >3MA8-A nrPDB Length = 534 Score = 658 bits (1698), Expect = 0.0, Method: Composition-based stats. Identities = 218/533 (40%), Positives = 304/533 (57%), Gaps = 30/533 (5%) Query: 55 FFQQQQLPAAMADTFLEHLCL-LDIDSEPVA-----ARSTSIIATIGPASRSVERLKEMI 108 +FQ A M+ T + CL +D P+A R T II TIGP+ +VE L +I Sbjct: 15 YFQGASTSAVMSCTLGKATCLGMDKICSPLADNDVTQRKTQIICTIGPSCNNVESLIGLI 74 Query: 109 KAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQ 168 GM++ARLNFSHG HE H +++ N+REA ++ + V I LDTKGPEIRTG+L+ Sbjct: 75 DKGMSVARLNFSHGDHESHFKTLQNIREAAKARP-----HSTVGIMLDTKGPEIRTGMLE 129 Query: 169 GGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVV 228 GG +EL G + +T D + GN+ + Y + + V +G + I DG +S V Sbjct: 130 GG--KPIELKAGQTLKITTD--YSMLGNSECISCSYSLLPKSVQIGSTVLIADGSLSTQV 185 Query: 229 QKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRDL-RFGVEHGVDIVFASF 287 +IG + +V +V N +G RK +NLPG +V LP + ++D D+ F +++ +D + SF Sbjct: 186 LEIGDDFIVCKVLNSVTIGERKNMNLPGCKVHLPIIGDKDRHDIVDFALKYNLDFIALSF 245 Query: 288 VRKASDVAAVRAALGPEGH-------GIKIISKIENHEGVKRFDEILEVSDGIMVARGDL 340 V+ +DV R + IKIISKIEN EGV FD I SDGIMVARGDL Sbjct: 246 VQNGADVQLCRQIISENTQYSNGIPSSIKIISKIENLEGVINFDSICSESDGIMVARGDL 305 Query: 341 GIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGAD 400 G+EIP EK+F+AQK MI +CN+AGKPVV ATQMLESMI RPTRAE +DVANAVLDG+D Sbjct: 306 GMEIPPEKIFVAQKCMISKCNVAGKPVVTATQMLESMIKSNRPTRAEMTDVANAVLDGSD 365 Query: 401 CIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAV 460 C+MLSGETA G FP +AV + + +AE + + L+ + + P E A AV Sbjct: 366 CVMLSGETANGAFPFDAVNVMSRVCAQAETCIDYPVLYHAIHSSVPKPVAVPEAIACSAV 425 Query: 461 EAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREP 520 E+A A II +T TG +A+L+S+YRP +IA T + AR + + RGV + Sbjct: 426 ESAHDVNAKLIITITETGNTARLISKYRPSQTIIACTAKPEVARGLKIARGVKTYVLN-- 483 Query: 521 PEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGS-GYTNIMRVLS 572 + + + K + GD I V G + G N+M+++ Sbjct: 484 ----SIHHSEVVISNALALAKEESLIESGDFAIAVHGVKESCPGSCNLMKIVR 532 >3KHD-A nrPDB Length = 520 Score = 657 bits (1696), Expect = 0.0, Method: Composition-based stats. Identities = 225/521 (43%), Positives = 312/521 (59%), Gaps = 18/521 (3%) Query: 55 FFQQQQLPAAMADTFLEHLCLLDIDSEPVAARSTSIIATIGPASRSVERLKEMIKAGMNI 114 +FQ + + + +L+ ++ + ++ T I+ T+GPA +SVE L ++I AGM+I Sbjct: 15 YFQGAAGASMQSAANITLRQILEPNNVNLRSKKTHIVCTLGPACKSVETLVKLIDAGMDI 74 Query: 115 ARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESE 174 R NFSHGSHE H E NV +A E + + LDTKGPEIRTG L+ E Sbjct: 75 CRFNFSHGSHEDHKEMFNNVLKAQELRPNCL-----LGMLLDTKGPEIRTGFLKN---KE 126 Query: 175 VELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPE 234 V L +GS++ + D F G+ + Y + + V G I I DG +S V + + Sbjct: 127 VHLKEGSKLKLVTDYEFL--GDETCIACSYKKLPQSVKPGNIILIADGSVSCKVLETHED 184 Query: 235 GLVTQVENGGVLGSRKGVNLPGAQVDLPGLSEQDVRD-LRFGVEHGVDIVFASFVRKASD 293 ++T+V N V+G RK +NLP +VDLP +SE+D D L F + G + + ASF++ A D Sbjct: 185 HVITEVLNSAVIGERKNMNLPNVKVDLPIISEKDKNDILNFAIPMGCNFIAASFIQSADD 244 Query: 294 VAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQ 353 V +R LGP G IKII KIEN EG+ FD+IL SDGIM+ARGDLG+EI EKVFLAQ Sbjct: 245 VRLIRNLLGPRGRHIKIIPKIENIEGIIHFDKILAESDGIMIARGDLGMEISPEKVFLAQ 304 Query: 354 KMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNF 413 K+MI +CNL GKP++ ATQMLESM PRPTRAE +DVANAVLDG DC+MLSGETA G F Sbjct: 305 KLMISKCNLQGKPIITATQMLESMTKNPRPTRAEVTDVANAVLDGTDCVMLSGETAGGKF 364 Query: 414 PVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIV 473 PVEAV + I EAEA + ++ L++ L A E A AVE A A+ II Sbjct: 365 PVEAVTIMSKICLEAEACIDYKLLYQSLVNAIETPISVQEAVARSAVETAESIQASLIIA 424 Query: 474 LTTTGRSAQLLSRYRPRAAVIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRV 533 LT TG +A+L+++Y+P ++A++ S + +++ RGV + + D + Sbjct: 425 LTETGYTARLIAKYKPSCTILALSASDSTVKCLNVHRGVTCI------KVGSFQGTDIVI 478 Query: 534 QFGIESGKLRGFLRVGDLVIVVTGWRPG-SGYTNIMRVLSI 573 + IE K R +VGD VI + G + SG TN+M+V+ I Sbjct: 479 RNAIEIAKQRNMAKVGDSVIAIHGIKEEVSGGTNLMKVVQI 519 >3GG8-A nrPDB Length = 511 Score = 644 bits (1662), Expect = 0.0, Method: Composition-based stats. Identities = 217/502 (43%), Positives = 306/502 (60%), Gaps = 18/502 (3%) Query: 75 LLDIDSE-PVAARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIAN 133 +L+ SE A T I+ T+GPA +V+ L +MI AGMN+ RLNFSHG HE HA ++ N Sbjct: 24 ILEPRSEEDWTAHRTRIVCTMGPACWNVDTLVKMIDAGMNVCRLNFSHGDHETHARTVQN 83 Query: 134 VREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRT 193 ++EA++ + +AI LDTKGPEIRTG L+ + L +G+ + + D + Sbjct: 84 IQEAMKQRPEAR-----LAILLDTKGPEIRTGFLKD--HKPITLQQGATLKIVTD--YNL 134 Query: 194 RGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVN 253 G+ T+ Y + + V G I I DG +S+ V ++G + ++TQ +N +G RK +N Sbjct: 135 IGDETTIACSYGALPQSVKPGNTILIADGSLSVKVVEVGSDYVITQAQNTATIGERKNMN 194 Query: 254 LPGAQVDLPGLSEQDVRD-LRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIIS 312 LP +V LP + E+D D L FG+ G + + ASFV+ A DV +R LGP G I+II Sbjct: 195 LPNVKVQLPVIGEKDKHDILNFGIPMGCNFIAASFVQSADDVRYIRGLLGPRGRHIRIIP 254 Query: 313 KIENHEGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQ 372 KIEN EG+ FDEIL +DGIM+ARGDLG+EIP EKVFLAQKMMI +CN+ GKPV+ ATQ Sbjct: 255 KIENVEGLVNFDEILAEADGIMIARGDLGMEIPPEKVFLAQKMMIAKCNVVGKPVITATQ 314 Query: 373 MLESMITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAV 432 MLESMI PRPTRAE +DVANAVLDG DC+MLSGETA G FPV V+ I EAE V Sbjct: 315 MLESMIKNPRPTRAEAADVANAVLDGTDCVMLSGETANGEFPVITVETMARICYEAETCV 374 Query: 433 YHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAA 492 + L+ + A P E A AVE A AA I+ LT TG++A+L+++YRP Sbjct: 375 DYPALYRAMCLAVPPPISTQEAVARAAVETAECVNAAIILALTETGQTARLIAKYRPMQP 434 Query: 493 VIAVTRSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLV 552 ++A++ S + + + RGV + + D ++ I K R + G+ + Sbjct: 435 ILALSASESTIKHLQVIRGVTTM------QVPSFQGTDHVIRNAIVVAKERELVTEGESI 488 Query: 553 IVVTGWRPG-SGYTNIMRVLSI 573 + V G + +G +N+++VL++ Sbjct: 489 VAVHGMKEEVAGSSNLLKVLTV 510 >1E0T-A nrPDB Length = 470 Score = 601 bits (1550), Expect = e-172, Method: Composition-based stats. Identities = 221/489 (45%), Positives = 283/489 (57%), Gaps = 21/489 (4%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 + T I+ TIGP + S E L +M+ AGMN+ RLNFSHG + H + I N+R + Sbjct: 2 KKTKIVCTIGPKTESEEMLAKMLDAGMNVMRLNFSHGDYAEHGQRIQNLRNVMSK----- 56 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + + AI LDTKGPEIRT L+GG +V L G T D + GN+ V V Y Sbjct: 57 -TGKTAAILLDTKGPEIRTMKLEGGN--DVSLKAGQTFTFTTDKS--VIGNSEMVAVTYE 111 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLS 265 + VG + +DDGLI + V I ++ +V N G LG KGVNLPG + LP L+ Sbjct: 112 GFTTDLSVGNTVLVDDGLIGMEVTAIEGNKVICKVLNNGDLGENKGVNLPGVSIALPALA 171 Query: 266 EQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEG-HGIKIISKIENHEGVKRFD 324 E+D +DL FG E GVD V ASF+RK SDV +R L G I IISKIEN EG+ FD Sbjct: 172 EKDKQDLIFGCEQGVDFVAASFIRKRSDVIEIREHLKAHGGENIHIISKIENQEGLNNFD 231 Query: 325 EILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPT 384 EILE SDGIMVARGDLG+EIP E+V AQKMMI +C A K V+ AT ML+SMI PRPT Sbjct: 232 EILEASDGIMVARGDLGVEIPVEEVIFAQKMMIEKCIRARKVVITATMMLDSMIKNPRPT 291 Query: 385 RAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRA 444 AE DVANA+LDG D +MLSGE+AKG +P+EAV + I + + R F R Sbjct: 292 DAEAGDVANAILDGTDAVMLSGESAKGKYPLEAVSIMATICERTDRVMNSRLEFNNDNRK 351 Query: 445 APLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAAR 504 + TE GAVE A K A I+V T G+SA+ + +Y P A ++A+T + + A Sbjct: 352 LRI----TEAVCRGAVETAEKLDAPLIVVATQGGKSARAVRKYFPDATILALTTNEKTAH 407 Query: 505 QVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGSGY 564 Q+ L +GV P L + E DD R G E G GD+V++V+G SG Sbjct: 408 QLVLSKGVVPQLVK---EITSTDDFYR---LGKELALQSGLAHKGDVVVMVSGALVPSGT 461 Query: 565 TNIMRVLSI 573 TN V + Sbjct: 462 TNTASVHVL 470 >2E28-A nrPDB Length = 587 Score = 598 bits (1541), Expect = e-171, Method: Composition-based stats. Identities = 226/494 (45%), Positives = 317/494 (64%), Gaps = 24/494 (4%) Query: 85 ARSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGS 144 R T I++TIGPAS SV++L ++++AGMN+ARLNFSHG HE H IAN+REA + Sbjct: 2 KRKTKIVSTIGPASESVDKLVQLMEAGMNVARLNFSHGDHEEHGRRIANIREAAKR---- 57 Query: 145 PLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDY 204 + R VAI LDTKGPEIRT ++ G +EL +GS++++++ G + V Y Sbjct: 58 --TGRTVAILLDTKGPEIRTHNMENGA---IELKEGSKLVISMS---EVLGTPEKISVTY 109 Query: 205 PNIVRVVPVGGRIYIDDGLISLVVQKIGPE--GLVTQVENGGVLGSRKGVNLPGAQVDLP 262 P+++ V VG +I +DDGLISL V + + +VT V NGGVL ++KGVN+PG +V+LP Sbjct: 110 PSLIDDVSVGAKILLDDGLISLEVNAVDKQAGEIVTTVLNGGVLKNKKGVNVPGVKVNLP 169 Query: 263 GLSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE-GHGIKIISKIENHEGVK 321 G++E+D D+ FG+ G+D + ASFVR+ASDV +R L I+II+KIEN EGV Sbjct: 170 GITEKDRADILFGIRQGIDFIAASFVRRASDVLEIRELLEAHDALHIQIIAKIENEEGVA 229 Query: 322 RFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKP 381 DEILE +DG+MVARGDLG+EIPAE+V L QK++I + N+ GKPV+ ATQML+SM P Sbjct: 230 NIDEILEAADGLMVARGDLGVEIPAEEVPLIQKLLIKKSNMLGKPVITATQMLDSMQRNP 289 Query: 382 RPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEEL 441 RPTRAE SDVANA+ DG D +MLSGETA G +PVEAVK H IA E A+ HR + + Sbjct: 290 RPTRAEASDVANAIFDGTDAVMLSGETAAGQYPVEAVKTMHQIALRTEQALEHRDILSQ- 348 Query: 442 RRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQ 501 R T+ A AAI+ T +G++ Q++++YRP+A +IAVT + Sbjct: 349 -RTKESQTTITDAIGQSVAHTALNLDVAAIVTPTVSGKTPQMVAKYRPKAPIIAVTSNEA 407 Query: 502 AARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPG 561 +R++ L GV+ EA + D + +++ G ++ GDLV++ G G Sbjct: 408 VSRRLALVWGVYT------KEAPHVNTTDEMLDVAVDAAVRSGLVKHGDLVVITAGVPVG 461 Query: 562 -SGYTNIMRVLSIS 574 +G TN+M+V IS Sbjct: 462 ETGSTNLMKVHVIS 475 >3T0T-A nrPDB Length = 606 Score = 597 bits (1539), Expect = e-171, Method: Composition-based stats. Identities = 211/491 (42%), Positives = 294/491 (59%), Gaps = 23/491 (4%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R T I+ TIGPAS S E ++++I AGMN+ARLNFSHGSHE H I +R+ + Sbjct: 23 RKTKIVCTIGPASESEEMIEKLINAGMNVARLNFSHGSHEEHKGRIDTIRKVAKRLD--- 79 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + VAI LDTKGPEIRT ++ G +EL +G++V+V+++ G V Y Sbjct: 80 ---KIVAILLDTKGPEIRTHNMKDGI---IELERGNEVIVSMN---EVEGTPEKFSVTYE 130 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIG--PEGLVTQVENGGVLGSRKGVNLPGAQVDLPG 263 N++ V VG I +DDGLI L V+ I + + + N G L ++KGVNLPG +V LPG Sbjct: 131 NLINDVQVGSYILLDDGLIELQVKDIDHAKKEVKCDILNSGELKNKKGVNLPGVRVSLPG 190 Query: 264 LSEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRF 323 ++E+D D+RFG++ VD + ASFVR+ SDV +R L + I + KIEN EG+ Sbjct: 191 ITEKDAEDIRFGIKENVDFIAASFVRRPSDVLEIREILEEQKANISVFPKIENQEGIDNI 250 Query: 324 DEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRP 383 +EILEVSDG+MVARGD+G+EIP EKV + QK +I +CN GKPV+ ATQML+SM PR Sbjct: 251 EEILEVSDGLMVARGDMGVEIPPEKVPMVQKDLIRQCNKLGKPVITATQMLDSMQRNPRA 310 Query: 384 TRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRR 443 TRAE SDVANA+ DG D +MLSGETA G +P EAVK IA AEAA +++L + + Sbjct: 311 TRAEASDVANAIYDGTDAVMLSGETAAGLYPEEAVKTMRNIAVSAEAAQDYKKLLSDRTK 370 Query: 444 AAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQAA 503 S I A AI+ T +G +A+ +S+YRP + +IAVT S + A Sbjct: 371 LVETSLV--NAIGISVAHTALNLNVKAIVAATESGSTARTISKYRPHSDIIAVTPSEETA 428 Query: 504 RQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPG-S 562 RQ + GV P++ + D + + + G + GDL+I+ G G + Sbjct: 429 RQCSIVWGVQPVVKKGR------KSTDALLNNAVATAVETGRVTNGDLIIITAGVPTGET 482 Query: 563 GYTNIMRVLSI 573 G TN+M++ + Sbjct: 483 GTTNMMKIHLV 493 >5WSC-A nrPDB Length = 475 Score = 547 bits (1409), Expect = e-156, Method: Composition-based stats. Identities = 175/492 (35%), Positives = 261/492 (53%), Gaps = 31/492 (6%) Query: 86 RSTSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSP 145 R I+ T+GPA++ + ++ +++AGM++AR+NFSHG ++ H + VR A S Sbjct: 6 RRGKIVCTLGPATQRDDLVRALVEAGMDVARMNFSHGDYDDHKVAYERVRVA------SD 59 Query: 146 LSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYP 205 + R V + D +GP+IR G G E G V +TV G+ + V Y Sbjct: 60 ATGRAVGVLADLQGPKIRLGRFASGATHWAE---GETVRITVGAC---EGSHDRVSTTYK 113 Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGLS 265 + + G R+ +DDG ++LVV + + +V V GG + KG++LPG V P LS Sbjct: 114 RLAQDAVAGDRVLVDDGKVALVVDAVEGDDVVCTVVEGGPVSDNKGISLPGMNVTAPALS 173 Query: 266 EQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDE 325 E+D+ DL F + GVD+V SFVR +DV V + G + +I+K+E E + + Sbjct: 174 EKDIEDLTFALNLGVDMVALSFVRSPADVELVHEVMDRIGRRVPVIAKLEKPEAIDNLEA 233 Query: 326 ILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTR 385 I+ D +MVARGDLG+E+P E+V L QK I KPV+ ATQML+SMI RPTR Sbjct: 234 IVLAFDAVMVARGDLGVELPLEEVPLVQKRAIQMARENAKPVIVATQMLDSMIENSRPTR 293 Query: 386 AETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAA 445 AE SDVANAVLDGAD +MLSGET+ G +P+ AV+ I E E A Sbjct: 294 AEASDVANAVLDGADALMLSGETSVGKYPLAAVRTMSRIICAVE---------ENSTAAP 344 Query: 446 PLSRDPTE---VTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSAQA 502 PL+ P V + A + + A A++ T +G + + L+R ++A T + Sbjct: 345 PLTHIPRTKRGVISYAARDIGERLDAKALVAFTQSGDTVRRLARLHTPLPLLAFTAWPEV 404 Query: 503 ARQVHLCRGVFPLLYREPPEAIWADDVDRRVQFGIESGKLRGFLRVGDLVIVVTGWRPGS 562 Q+ + G + P+ D + R+V + +L + R GDLV++V G PG+ Sbjct: 405 RSQLAMTWGTETFIV---PKMQSTDGMIRQVDKSLL--ELARYKR-GDLVVIVAGAPPGT 458 Query: 563 -GYTNIMRVLSI 573 G TN++ V I Sbjct: 459 VGSTNLIHVHRI 470 >3QTG-A nrPDB Length = 461 Score = 450 bits (1158), Expect = e-127, Method: Composition-based stats. Identities = 129/458 (28%), Positives = 215/458 (46%), Gaps = 38/458 (8%) Query: 84 AARSTSIIATIGPASRSVERLKEMIK--AGMNIARLNFSHGSHEYHAESIANVREAVESF 141 A T +AT+GP++ V R E+IK ++ R+N +H S I EAV S+ Sbjct: 13 ARNLTKRVATLGPST-DVLRPDELIKFLDLVDGVRINLAHASPNEVKFRI----EAVRSY 67 Query: 142 AGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVW 201 + RP+A+ +D KGP IR G E E+VK F+ ++ + Sbjct: 68 EKA--KNRPLAVIVDLKGPSIRVGSTSPINVQEGEVVK-----------FKLSDKSDGTY 114 Query: 202 VDYPN--IVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQV 259 + PN V I + DG + L V G + + E+ GV+ K + + G Sbjct: 115 IPVPNKAFFSAVEQNDVILMLDGRLRLKVTNTGSDWIEAVAESSGVITGGKAIVVEGKDY 174 Query: 260 DLPGLSEQDVRDLR--FGVEHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENH 317 D+ +E+DV L+ + +D V S + DV +VR+ L G ++ KIE Sbjct: 175 DISTPAEEDVEALKAISPIRDNIDYVAISLAKSCKDVDSVRSLLTELGFQSQVAVKIETK 234 Query: 318 EGVKRFDEILEVSDGIMVARGDLGIEIPAEKVFLAQKMMIGRCNLAGKPVVCATQMLESM 377 V +E+++ SD ++VARGDLG+ + + + Q+ ++ GKP+ ATQ+L+SM Sbjct: 235 GAVNNLEELVQCSDYVVVARGDLGLHYGLDALPIVQRRIVHTSLKYGKPIAVATQLLDSM 294 Query: 378 ITKPRPTRAETSDVANAVLDGADCIMLSGETAKGNFPVEAVKMQHAIAREAEAAVYHRQL 437 + P PTRAE +DV G D + L+ ETA G +P+ AV I E + Sbjct: 295 QSSPIPTRAEINDVFTTASMGVDSLWLTNETASGKYPLAAVSWLSRILMNVEYQIPQ--- 351 Query: 438 FEELRRAAPLSRDPTEVTAIGAVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVT 497 +PL ++ + A G VE A + A I+V + +G A+ ++++RPR V T Sbjct: 352 -------SPLLQNSRDRFAKGLVELA-QDLGANILVFSMSGTLARRIAKFRPRGVVYVGT 403 Query: 498 RSAQAARQVHLCRGVFPLLYREPPEAIWADDVDRRVQF 535 + + AR + + + PL P + + +++ + Sbjct: 404 PNVRVARSLSIVWALEPLYI---PAENYEEGLEKLISL 438 >1DXF-A nrPDB Length = 256 Score = 43.9 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 27/98 (27%), Positives = 36/98 (36%), Gaps = 10/98 (10%) Query: 277 EHGVDIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEI--LEVSDGIM 334 G+ V S +A+ V I I+ +IE+ +GV D I E DGI Sbjct: 117 PEGIRGVSVS--HRANMFGTVADYFAQSNKNITILVQIESQQGVDNVDAIAATEGVDGIF 174 Query: 335 VARGDLGI---EIPAEKVFLAQKMMIGRCNLA---GKP 366 V DL + QK + N A GKP Sbjct: 175 VGPSDLAAALGHLGNASHPDVQKAIQHIFNRASAHGKP 212 >3QLL-A nrPDB Length = 316 Score = 39.3 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 34/175 (19%), Positives = 68/175 (38%), Gaps = 15/175 (8%) Query: 206 NIVRVVPVGGRIYIDDGLISLVVQKIGPEGLVTQVENGGVLGSRKGVNLPGAQVDLPGL- 264 + G + I D + V + E + + L SR +LP + + GL Sbjct: 58 RFAKAAENGADVAIID--LEDSVSQADKEQARQKAIS--YLSSRPATSLP-LALRINGLD 112 Query: 265 SEQDVRDLRFGVEHGV--DIVFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKR 322 + + D+ +E G D + A+ + + + G ++I IE+ G+ Sbjct: 113 TRAGIEDIHALLECGSLPDYLVLPKTESAAHLQILDRLMMFAGSDTRLIGIIESVRGLNA 172 Query: 323 FDEILEVSD---GIMVARGDLGIEIPA----EKVFLAQKMMIGRCNLAGKPVVCA 370 + I + G++ D+ +I A E + LA+ ++ C + G P + A Sbjct: 173 VESIAAATPKLAGLIFGAADMAADIGAASTWEPLALARARLVSACAMNGIPAIDA 227 >4FEZ-A nrPDB Length = 388 Score = 37.7 bits (86), Expect = 0.015, Method: Composition-based stats. Identities = 27/120 (22%), Positives = 48/120 (40%), Gaps = 15/120 (12%) Query: 47 LTQELGTAFF--------QQQQLPAAMADTFLEHLCLLDIDSEPVAAR----STSIIATI 94 L QE G F Q Q+ +S+P A + + A + Sbjct: 66 LAQEGGIGFIHKNMSIEQQAAQVHQVKIFESGGAKDFHKAESKPNACKDEQGRLRVGAAV 125 Query: 95 GPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIA 154 G A + ER+K +++AG+++ ++ SHG E + +RE ++ + VA A Sbjct: 126 GAAPGNEERVKALVEAGVDVLLIDSSHGHSE---GVLQRIRETRAAYPHLEIIGGNVATA 182 >4FXS-A nrPDB Length = 496 Score = 37.4 bits (85), Expect = 0.020, Method: Composition-based stats. Identities = 17/68 (25%), Positives = 34/68 (50%), Gaps = 3/68 (4%) Query: 87 STSIIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESFAGSPL 146 + A +G A + ER+K +++AG+++ ++ SHG E + +RE ++ + Sbjct: 219 RLRVGAAVGAAPGNEERVKALVEAGVDVLLIDSSHGHSE---GVLQRIRETRAAYPHLEI 275 Query: 147 SYRPVAIA 154 VA A Sbjct: 276 IGGNVATA 283 >3IV8-A nrPDB Length = 381 Score = 35.0 bits (79), Expect = 0.082, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 56/142 (39%), Gaps = 24/142 (16%) Query: 93 TIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAESIANVREAVESF--AGSPLSYR- 149 T+ P + E +++++KAG+ + + ++ ++ +S + A +P+ R Sbjct: 170 TLAPENNKPEHIEKLVKAGI-VVSIGHTNATYSEARKSFESGITFATHLFNAMTPMVGRE 228 Query: 150 --PVAIALDTKGPEIRTGILQGGPESE------VELVKGSQVLVTVDPAFRTRGNANTVW 201 V DT PE+ GI+ G + +KG ++++ D + Sbjct: 229 PGVVGAIYDT--PEVYAGIIADGFHVDYANIRIAHKIKGEKLVLVTDATAPAGAEMDYF- 285 Query: 202 VDYPNIVRVVPVGGRIYIDDGL 223 + VG ++Y DG Sbjct: 286 ---------IFVGKKVYYRDGK 298 >2YNM-D nrPDB Length = 530 Score = 33.9 bits (76), Expect = 0.18, Method: Composition-based stats. Identities = 34/189 (17%), Positives = 59/189 (31%), Gaps = 40/189 (21%) Query: 162 IRTGILQGGPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDD 221 +R G + +G + RG+ V Y G + Sbjct: 17 MRIATSMKGLHYVLHAPQGDTYADLLFTMIERRGS--RPPVTYTTFQARDLGGDTAELVK 74 Query: 222 GLISLVVQKIGPEGLV----TQVE----NGGVLGSRKGVNLPGAQVDLPGLSEQD----- 268 G I V++ PE L+ E G L G+N+P ++LP S+++ Sbjct: 75 GHIFEAVERFKPEALLVGESCTAELIQDQPGSLAKGMGLNIPIVSLELPAYSKKENWGAS 134 Query: 269 --------------VRDLRFGVEHG---------VDIVFASFV--RKASDVAAVRAALGP 303 D + V+++ S + R DV ++ LG Sbjct: 135 ETFYQLIRGLLKEISEDSSNNAKQSWQEEGRRPRVNLLGPSLLGFRCRDDVLEIQKILGE 194 Query: 304 EGHGIKIIS 312 G I +I+ Sbjct: 195 NGIDINVIA 203 >2YCL-A nrPDB Length = 445 Score = 33.1 bits (74), Expect = 0.36, Method: Composition-based stats. Identities = 42/208 (20%), Positives = 69/208 (33%), Gaps = 30/208 (14%) Query: 22 DLAKSILIGAPGGPAGYLRRASVAQLTQELG--TAFFQQQQLPAAMADTFLEHLCLLDID 79 D AK +L A P ++ + E+G T F+ D EH C L I Sbjct: 47 DEAKELLESASAPPVALIKVGK-GEKVLEIGHETVLFRH--------DKRFEHPCGLAIL 97 Query: 80 SEPVAARSTSIIATIGPASRSVERLKEMIKA------GMNIARLNFSHGSHEYHAESIAN 133 E + G VE++ +++ +N+ L S A+++A Sbjct: 98 VEDTLSE--------GEIKERVEKINKLVFDRVGQMHSVNLVALKGSSQDAATFAKAVAT 149 Query: 134 VREAVESFAGSPLSYRPVAIALDTKGPE--IRTGILQGGPESEVELVKGSQVLVTVDPAF 191 RE + + +A AL+T+G + E VEL K V +TV Sbjct: 150 AREVTDLPFILIGTPEQLAAALETEGANNPLLYAATADNYEQMVELAKKYNVPLTVSAKG 209 Query: 192 RTRGNA---NTVWVDYPNIVRVVPVGGR 216 + Y N++ Sbjct: 210 LDALAELVQKITALGYKNLILDPQPENI 237 >2VWT-A nrPDB Length = 267 Score = 32.7 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 38/91 (41%), Gaps = 9/91 (9%) Query: 283 VFASFVRKASDVAAVRAALGPEGHGIKIISKIENHEGVKRFDEILEVS--DGIMVARGDL 340 V AS R A+ + + + ++ ++E+ + DEIL+V DG+ + DL Sbjct: 122 VGASVAR-AARWGRIENYMAQVNDSLCLLVQVESKTALDNLDEILDVEGIDGVFIGPADL 180 Query: 341 GIEIPAEKV---FLAQKMM---IGRCNLAGK 365 + Q+++ I R AGK Sbjct: 181 SASLGYPDNAGHPEVQRIIETSIRRIRAAGK 211 >1VRD-A nrPDB Length = 494 Score = 32.0 bits (71), Expect = 0.73, Method: Composition-based stats. Identities = 31/157 (19%), Positives = 62/157 (39%), Gaps = 21/157 (13%) Query: 75 LLDIDSEPVAARSTS----IIATIGPASRSVERLKEMIKAGMNIARLNFSHGSHEYHAES 130 ++ + P AAR + A +G + ++ER+++++KAG+++ ++ +HG H+ Sbjct: 209 IMSVIEHPNAARDEKGRLLVGAAVGTSPETMERVEKLVKAGVDVIVIDTAHG----HSRR 264 Query: 131 -IANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPES-EVELVKGSQVLVTVD 188 I + + P+ VA PE +++ G ++ +V + GS + Sbjct: 265 VIETLEMIKADYPDLPVVAGNVAT------PEGTEALIKAGADAVKVGVGPGS---ICTT 315 Query: 189 PAFRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLIS 225 G V V I DG I Sbjct: 316 RVVAGVGVPQLTAV--MECSEVARKYDVPIIADGGIR 350 >4L80-A nrPDB Length = 348 Score = 31.2 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 27/69 (39%), Gaps = 6/69 (8%) Query: 268 DVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALG------PEGHGIKIISKIENHEGVK 321 D+ ++ V + +D++ V D+ V L I I + +E +G+ Sbjct: 104 DIAEIVAAVGNKLDVIMIPKVEGPWDIHFVDQYLALLEARHQIKKPILIHALLETAQGMV 163 Query: 322 RFDEILEVS 330 +EI S Sbjct: 164 NLEEIAGAS 172 >1F0N-A nrPDB Length = 285 Score = 30.4 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 22/42 (52%) Query: 459 AVEAAFKCCAAAIIVLTTTGRSAQLLSRYRPRAAVIAVTRSA 500 + A K +A I L+ G SA +L+ Y P+ + A + SA Sbjct: 110 SANRAVKPTGSAAIGLSMAGSSAMILAAYHPQQFIYAGSLSA 151 >3M6A-A nrPDB Length = 543 Score = 29.6 bits (65), Expect = 3.3, Method: Composition-based stats. Identities = 33/160 (20%), Positives = 61/160 (38%), Gaps = 18/160 (11%) Query: 158 KGPEIRTGILQG----GPESEVELVKGSQVLVTVDPAFRTRGNANTVWVDYPNIVRVVPV 213 KG I TG L ++ V+ + ++P F + + + + V + + P Sbjct: 380 KGKLILTGKLGDVMRESAQAAFSYVRSKTEELGIEPDFHEKYDIH-IHVPEGAVPKDGPA 438 Query: 214 GGR------IYIDDGL-ISLVVQKIGPEGLVTQVENGGVLGSRK-GVNLPG-AQVDLPGL 264 G + G +S V G L +V G L + G + G + P Sbjct: 439 AGITMATALVSALTGRAVSREVGMTGEITLRGRVLPIGGLKEKALGAHRAGLTTIIAPKD 498 Query: 265 SEQDVRDLRFGVEHGVDIVFASFVRKASDVAAVRAALGPE 304 +E+D+ D+ V G+ + AS + +V A +G + Sbjct: 499 NEKDIEDIPESVREGLTFILASHL---DEVLE-HALVGEK 534 >4Z87-A nrPDB Length = 525 Score = 29.6 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 33/183 (18%), Positives = 74/183 (40%), Gaps = 15/183 (8%) Query: 68 TFLEHLCLLDIDSEPVAARST---SIIA--TIGPASRSVERLKEMIKAGMNIARLNFSHG 122 + L L+ S P+A++S ++ IG +RL +++AG+++ L+ S G Sbjct: 225 SMLSRTDLMKNQSYPLASKSADTKQLLCGAAIGTIDADRQRLAMLVEAGLDVVVLDSSQG 284 Query: 123 SHEYHAESIANVREA---VESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVEL-- 177 + + I ++E ++ AG+ ++ A + +R G+ G E+ Sbjct: 285 NSVFQINMIKWIKETFPDLQVIAGNVVTREQAASLIHAGADGLRIGMGSGSICITQEVMA 344 Query: 178 ---VKGSQVLVTVDPA--FRTRGNANTVWVDYPNIVRVVPVGGRIYIDDGLISLVVQKIG 232 +G+ V A F A+ + +I + + +G + G+++ + G Sbjct: 345 CGRPQGTAVYNVTQFANQFGVPCIADGGVQNIGHITKAIALGASTVMMGGMLAGTTESPG 404 Query: 233 PEG 235 Sbjct: 405 EYF 407 >2D2A-A nrPDB Length = 145 Score = 29.6 bits (65), Expect = 3.8, Method: Composition-based stats. Identities = 23/84 (27%), Positives = 32/84 (38%), Gaps = 14/84 (16%) Query: 244 GVLGSRKGVNLPGAQ---VDLPGLSEQDVRDLRF---GVEHGVDIVFASFVRKASDVAAV 297 G++G R GV G L +SE D DL F G + V + F+ ++V V Sbjct: 60 GMVGVRLGVKQTGCAGFGYVLDSVSEPDKDDLLFEHDGAKLFVPLQAMPFI-DGTEVDFV 118 Query: 298 RAALGPEGHGIKIISKIENHEGVK 321 R L I K N + Sbjct: 119 REGLNQ-------IFKFHNPKAQN 135 >5VMS-A nrPDB Length = 548 Score = 29.3 bits (64), Expect = 4.9, Method: Composition-based stats. Identities = 15/60 (25%), Positives = 27/60 (45%), Gaps = 2/60 (3%) Query: 117 LNFSHGSHEYHAESIANVREAVESFAGSPLSYRPVAIALDTKGPEIRTGILQGGPESEVE 176 LN H ++++ A+ N +VES+ + +P + GP IRT + E + Sbjct: 361 LNIPHITYDHVADDRKNDGYSVESYENTVR--KPFGFLDPSTGPFIRTSSFTDDLDMEGD 418 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.134 0.360 Lambda K H 0.267 0.0414 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 20,974,617 Number of Sequences: 36641 Number of extensions: 860832 Number of successful extensions: 2595 Number of sequences better than 10.0: 35 Number of HSP's better than 10.0 without gapping: 39 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 2440 Number of HSP's gapped (non-prelim): 67 length of query: 574 length of database: 10,336,785 effective HSP length: 102 effective length of query: 472 effective length of database: 6,599,403 effective search space: 3114918216 effective search space used: 3114918216 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.5 bits)