BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P30260 (824 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5G04-F nrPDB 1718 0.0 5G05-C nrPDB 122 4e-28 5KHR-J nrPDB 71 2e-12 1W3B-A nrPDB 69 6e-12 6B85-J nrPDB 67 4e-11 5G04-X nrPDB 61 2e-09 5LVV-A nrPDB 45 1e-04 5A01-A nrPDB 45 2e-04 5JJT-A nrPDB 42 0.001 6AF0-A nrPDB 40 0.004 6FO1-G nrPDB 38 0.019 1IHG-A nrPDB 37 0.037 5DSE-A nrPDB 36 0.080 2GW1-A nrPDB 36 0.084 5AEM-A nrPDB 35 0.099 5ZYQ-A nrPDB 34 0.28 4ZLH-A nrPDB 34 0.28 1O1S-A nrPDB 33 0.44 2H6F-A nrPDB 33 0.49 4JA9-A nrPDB 33 0.50 5FZQ-A nrPDB 33 0.56 2BED-A nrPDB 32 0.76 4UZY-A nrPDB 32 0.78 1A17-A nrPDB 32 0.83 6AHD-N nrPDB 32 0.86 5OMP-A nrPDB 32 0.95 5NNP-A nrPDB 32 1.00 4HOQ-A nrPDB 32 1.0 1QZ2-A nrPDB 31 2.3 1KT1-A nrPDB 31 2.8 5WVI-K nrPDB 31 2.8 2C2L-A nrPDB 30 2.9 6EF1-K nrPDB 30 3.7 5VHO-B nrPDB 30 4.2 1HH8-A nrPDB 30 4.7 2WAU-A nrPDB 30 5.0 5VFP-B nrPDB 30 5.2 5UDI-A nrPDB 29 6.5 5VHF-B nrPDB 29 6.8 4AR2-A nrPDB 29 7.1 4GYO-A nrPDB 29 8.7 >5G04-F nrPDB Length = 824 Score = 1718 bits (4450), Expect = 0.0, Method: Compositional matrix adjust. Identities = 824/824 (100%), Positives = 824/824 (100%) Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL Sbjct: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 Query: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL Sbjct: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 Query: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL Sbjct: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 Query: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI Sbjct: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 Query: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN Sbjct: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 Query: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP Sbjct: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360 Query: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ Sbjct: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420 Query: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN Sbjct: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480 Query: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS Sbjct: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY Sbjct: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK Sbjct: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK Sbjct: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID Sbjct: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 Query: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF Sbjct: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 >5G05-C nrPDB Length = 597 Score = 122 bits (307), Expect = 4e-28, Method: Compositional matrix adjust. Identities = 61/179 (34%), Positives = 105/179 (58%) Query: 498 TGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSK 557 + +++ QI AY + + +A IF+E+R+ + YR+E M+ +S L+ LS L+ Sbjct: 262 SSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAH 321 Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 +L ++DK E C GN +SL+ +H+ A +FQRA++++P Y A+TL+GHE++ + Sbjct: 322 NLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNT 381 Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 A+ +R+AI VN R Y AWYGLG Y + ++++A + P S +L +G Sbjct: 382 SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALG 440 Score = 34.3 bits (77), Expect = 0.24, Method: Compositional matrix adjust. Identities = 50/216 (23%), Positives = 81/216 (37%), Gaps = 31/216 (14%) Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAW-- 638 RE + + +A ++D Y Y ++ + L +E A+ F A V P H+ AW Sbjct: 152 RELRVELSKKHQARELDGFGLYLYGVVLRKLDLVKE---AIDVFVEATHVLPLHWGAWLE 208 Query: 639 -----------------------YGLGMIYYKQEKFSLAEMHFQKALDIN-PQSSVLLCH 674 + L IY + + A +Q +D+ +SS ++ Sbjct: 209 LCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQNLIDVGFSKSSYIVSQ 268 Query: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQEL-EELKQIV 733 I V H ++ +KAL N+ DP + S L KS L L L +I Sbjct: 269 IAVAYHNIRDIDKALSIFNELRKQDPYR-IENMDTFSNLLYVRSMKSELSYLAHNLCEID 327 Query: 734 PKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 +IG Y Q A + F A+ L+P+ Sbjct: 328 KYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPR 363 Score = 29.6 bits (65), Expect = 5.8, Method: Compositional matrix adjust. Identities = 24/128 (18%), Positives = 50/128 (39%) Query: 503 CQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDM 562 C IG Y S++ +A F ++ + + ++ A + ++ Sbjct: 335 CVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNTSAAIQAYRHAIEV 394 Query: 563 DKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622 +K AW G + + + + +++RA Q+ PN + LG + +L +A Sbjct: 395 NKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGECYEKLNQLVEAKK 454 Query: 623 CFRNAIRV 630 C+ A V Sbjct: 455 CYWRAYAV 462 >5KHR-J nrPDB Length = 620 Score = 71.2 bits (173), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 72/292 (24%), Positives = 125/292 (42%), Gaps = 29/292 (9%) Query: 487 ILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHL 546 ++S H+YN + +C ++ S V + + + ++ TL L Sbjct: 234 VVSLAERHYYNCDFKMCY---------------KLTSVVMEKDPFHASCLPVHIGTLVEL 278 Query: 547 QKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREH--DIAIKFFQRAIQVDPNYAYAY 604 K L LS L D+ ++P +W A G C+ L H + A ++ +A ++ Y A+ Sbjct: 279 NKANELFYLSHKLVDLYPSNPVSWFAVG-CYYLMVGHKNEHARRYLSKATTLEKTYGPAW 337 Query: 605 TLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 GH F + E D+A+A + A ++ + +G+ Y LAE F +AL I Sbjct: 338 IAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSI 397 Query: 665 NPQSSVLLCHIGVVQH---ALKKSEKA-LDTLNK------AIVIDPKNPLCKFHRASVLF 714 P+ ++ +GVV K +EK LD L K + +D PL + V Sbjct: 398 APEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN-NLGHVCR 456 Query: 715 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 +KY AL + ++P+ + Y IG ++ +G A+ F A+ L Sbjct: 457 KLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGL 508 >1W3B-A nrPDB Length = 388 Score = 69.3 bits (168), Expect = 6e-12, Method: Compositional matrix adjust. Identities = 53/222 (23%), Positives = 103/222 (46%), Gaps = 6/222 (2%) Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 N AW G F+ Q E +AI F++A+ +DPN+ AY LG+ D+A+A + Sbjct: 167 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 226 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684 A+ ++P H L +YY+Q LA +++A+++ P C++ Sbjct: 227 LRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGS 286 Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 +A D N A+ + P + + A++ + A++ + ++ P+ + + + Sbjct: 287 VAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLA 346 Query: 745 KVYKKLGQTHLALMNFSWAMDLDPKGAN------NQIKEAID 780 V ++ G+ ALM++ A+ + P A+ N +KE D Sbjct: 347 SVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQD 388 Score = 56.6 bits (135), Expect = 4e-08, Method: Compositional matrix adjust. Identities = 44/201 (21%), Positives = 92/201 (45%) Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNA 627 EA+ GN + + + AI+ ++ A+++ P++ Y L V +++ A+ + +A Sbjct: 68 EAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQAYVSA 127 Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 ++ NP Y LG + + A+ + KA++ P +V ++G V +A + Sbjct: 128 LQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWL 187 Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747 A+ KA+ +DP + +VL + A+ + P ++V+ + VY Sbjct: 188 AIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVY 247 Query: 748 KKLGQTHLALMNFSWAMDLDP 768 + G LA+ + A++L P Sbjct: 248 YEQGLIDLAIDTYRRAIELQP 268 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 55/237 (23%), Positives = 100/237 (42%), Gaps = 7/237 (2%) Query: 555 LSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT 614 L D D N A AAG+ + A++ + A+Q +P+ + LG+ Sbjct: 96 LKPDFIDGYINLAAALVAAGDM-------EGAVQAYVSALQYNPDLYCVRSDLGNLLKAL 148 Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH 674 L++A AC+ AI P AW LG ++ Q + LA HF+KA+ ++P + Sbjct: 149 GRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYIN 208 Query: 675 IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734 +G V + ++A+ +A+ + P + + + A V + A+ ++ P Sbjct: 209 LGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYRRAIELQP 268 Query: 735 KESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791 Y + K+ G A ++ A+ L P A++ A KR + EE + Sbjct: 269 HFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNIEEAV 325 Score = 52.8 bits (125), Expect = 6e-07, Method: Compositional matrix adjust. Identities = 49/201 (24%), Positives = 91/201 (45%), Gaps = 1/201 (0%) Query: 550 VALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH 609 +A+ K +T +D N +A+ GN R D A+ + RA+ + PN+A + L Sbjct: 187 LAIHHFEKAVT-LDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLAC 245 Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSS 669 + +D A+ +R AI + P +A+ L ++ + AE + AL + P + Sbjct: 246 VYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHA 305 Query: 670 VLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729 L ++ ++ E+A+ KA+ + P+ + ASVL K + AL +E Sbjct: 306 DSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEA 365 Query: 730 KQIVPKESLVYFLIGKVYKKL 750 +I P + Y +G K++ Sbjct: 366 IRISPTFADAYSNMGNTLKEM 386 Score = 44.3 bits (103), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 78/191 (40%) Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640 R D + F AI+ +P A AY+ LG+ + +L +A+ +R+A+R+ P + + Sbjct: 47 RRLDRSAHFSTLAIKQNPLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYIN 106 Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700 L A + AL NP + +G + AL + E+A KAI P Sbjct: 107 LAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQP 166 Query: 701 KNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760 + + V A + A+ E+ + P Y +G V K+ A+ + Sbjct: 167 NFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAY 226 Query: 761 SWAMDLDPKGA 771 A+ L P A Sbjct: 227 LRALSLSPNHA 237 >6B85-J nrPDB Length = 223 Score = 66.6 bits (161), Expect = 4e-11, Method: Composition-based stats. Identities = 35/117 (29%), Positives = 65/117 (55%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 A + +++AI++DPN A A+ LLG + LD+A ++ AI + P +AW LG + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKN 702 K + A ++KA++++P+ + +G V L + ++A + KAI +DP + Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPND 216 Score = 57.4 bits (137), Expect = 3e-08, Method: Composition-based stats. Identities = 31/110 (28%), Positives = 55/110 (50%) Query: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEE 616 K ++D N AW G+ + D A + +++AI++ PN A A+ LG Sbjct: 105 KKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGR 164 Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 LD+A ++ AI ++P AW LG + K + A ++KA++++P Sbjct: 165 LDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDP 214 Score = 45.8 bits (107), Expect = 8e-05, Method: Composition-based stats. Identities = 43/168 (25%), Positives = 71/168 (42%), Gaps = 34/168 (20%) Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 A AY +LG L L A ++ AI ++P AW LG + K ++ A ++K Sbjct: 81 ALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKK 140 Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 A+++ P + +G V L + ++A + KAI +DP++ Sbjct: 141 AIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPED-----------------A 183 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 A +EL GKV +KLG+ A + A++LDP Sbjct: 184 EAWKEL-----------------GKVLEKLGRLDEAAEAYKKAIELDP 214 Score = 38.9 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 24/84 (28%), Positives = 44/84 (52%) Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747 A + KAI +DP + L SVL ++ A + ++ ++ P ++ + +GKV Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 748 KKLGQTHLALMNFSWAMDLDPKGA 771 +KLG+ A + A++LDP+ A Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDA 183 >5G04-X nrPDB Length = 599 Score = 61.2 bits (147), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 72/323 (22%), Positives = 135/323 (41%), Gaps = 18/323 (5%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 +L + YF + + F + + ++ Y ++GM++Y L + + L L Sbjct: 273 LLGSLADLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLF 332 Query: 561 DMDKNSPEAWCAAGNCFSL-QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDK 619 ++ E W +G C S + + A+ +AIQ++ N A L G + + Sbjct: 333 NISDQHAEPWVVSG-CHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQE 391 Query: 620 ALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIG 676 A+ FR AIR+ P + + GL Y A + + K L N Q+ LL + Sbjct: 392 AIIHFREAIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVC 451 Query: 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKE 736 + + EKA L+KA+ P +A +L +KY+ + L+ + + Sbjct: 452 LEDPVTQ--EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDG---IALLRNALANQ 506 Query: 737 S--LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI--T 792 S +++ ++G + + A+ +S A+ LDP N K + + +E P T Sbjct: 507 SDCVLHRILGDFLVAVNEYQEAMDQYSIALSLDP----NDQKSLEGMQKMEKEESPTDAT 562 Query: 793 QEEQIMGTDESQESSMTDADDTQ 815 QEE + + S E + D++ Sbjct: 563 QEEDVDDMEGSGEEGDLEGSDSE 585 >5LVV-A nrPDB Length = 749 Score = 45.4 bits (106), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/113 (26%), Positives = 55/113 (48%), Gaps = 3/113 (2%) Query: 567 PEAWCAAGNCFS-LQREHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC 623 PE A N S LQ++ + A+ ++ AI++ P +A AY+ +G+ +++ AL C Sbjct: 61 PEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQGALQC 120 Query: 624 FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 + AI++NP +A L I+ A ++ AL + P C++ Sbjct: 121 YTRAIQINPAFADAHSNLASIHKDSGNIPEAIASYRTALKLKPDFPDAYCNLA 173 Score = 43.9 bits (102), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 39/196 (19%), Positives = 86/196 (43%), Gaps = 16/196 (8%) Query: 575 NCFSLQREH---DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVN 631 N +++RE + A++ +++A++V P +A A++ L +L +AL ++ AIR++ Sbjct: 35 NLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRIS 94 Query: 632 PRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDT 691 P +A+ +G + + A + +A+ INP + ++ + +A+ + Sbjct: 95 PTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIAS 154 Query: 692 LNKAIVIDPKNP--LCKF-HRASVLFANEKYKSALQEL----------EELKQIVPKESL 738 A+ + P P C H ++ Y +++L L + P S+ Sbjct: 155 YRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSM 214 Query: 739 VYFLIGKVYKKLGQTH 754 +Y L K + + H Sbjct: 215 LYPLSHGFRKAIAERH 230 Score = 31.2 bits (69), Expect = 1.7, Method: Compositional matrix adjust. Identities = 23/87 (26%), Positives = 42/87 (48%) Query: 686 EKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGK 745 E+A+ KA+ + P+ + ASVL K + AL +E +I P + Y +G Sbjct: 47 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 106 Query: 746 VYKKLGQTHLALMNFSWAMDLDPKGAN 772 K++ AL ++ A+ ++P A+ Sbjct: 107 TLKEMQDVQGALQCYTRAIQINPAFAD 133 Score = 30.0 bits (66), Expect = 3.8, Method: Compositional matrix adjust. Identities = 30/135 (22%), Positives = 57/135 (42%) Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 H ++ L I +Q A ++KAL++ P+ + ++ V K ++AL Sbjct: 29 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 88 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 +AI I P + + L + + ALQ QI P + + + ++K G Sbjct: 89 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 148 Query: 754 HLALMNFSWAMDLDP 768 A+ ++ A+ L P Sbjct: 149 PEAIASYRTALKLKP 163 >5A01-A nrPDB Length = 710 Score = 44.7 bits (104), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 23/91 (25%), Positives = 45/91 (49%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 A+ ++ AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A L I+ Sbjct: 60 ALMHYKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIH 119 Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 A ++ AL + P C++ Sbjct: 120 KDSGNIPEAIQSYRTALKLKPDFPDAYCNLA 150 Score = 42.0 bits (97), Expect = 0.001, Method: Compositional matrix adjust. Identities = 41/199 (20%), Positives = 85/199 (42%), Gaps = 16/199 (8%) Query: 575 NCFSLQREH---DIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVN 631 N +++RE + A + + +A++V P++A A++ L +L +AL ++ AIR+ Sbjct: 12 NLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQ 71 Query: 632 PRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDT 691 P +A+ +G + + S A + +A+ INP + ++ + +A+ + Sbjct: 72 PTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQS 131 Query: 692 LNKAIVIDPKNP--LCKF-HRASVLFANEKYKSALQEL----------EELKQIVPKESL 738 A+ + P P C H ++ Y +++L L + P S+ Sbjct: 132 YRTALKLKPDFPDAYCNLAHCLQIVCDWTDYDIRMKKLVSIVTEQLEKNRLPSVHPHHSM 191 Query: 739 VYFLIGKVYKKLGQTHLAL 757 +Y L K + H L Sbjct: 192 LYPLTHDCRKAIAARHANL 210 Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust. Identities = 18/75 (24%), Positives = 40/75 (53%) Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNA 627 +A+ GN ++ A++ + RAIQ++P +A A++ L + + +A+ +R A Sbjct: 76 DAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAIQSYRTA 135 Query: 628 IRVNPRHYNAWYGLG 642 +++ P +A+ L Sbjct: 136 LKLKPDFPDAYCNLA 150 Score = 30.0 bits (66), Expect = 4.9, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 40/87 (45%) Query: 686 EKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGK 745 E+A KA+ + P + ASVL K K AL +E +I P + Y +G Sbjct: 24 EEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIRIQPTFADAYSNMGN 83 Query: 746 VYKKLGQTHLALMNFSWAMDLDPKGAN 772 K+L AL ++ A+ ++P A+ Sbjct: 84 TLKELQDVSGALQCYTRAIQINPAFAD 110 >5JJT-A nrPDB Length = 479 Score = 41.6 bits (96), Expect = 0.001, Method: Compositional matrix adjust. Identities = 30/136 (22%), Positives = 63/136 (46%), Gaps = 8/136 (5%) Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705 +K K+S A + KA+++N ++V + L++ A+ +KAI +D + Sbjct: 20 FKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKG 79 Query: 706 KFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMD 765 + R + A K+K AL++ +++K++ P + +KL + A+M + Sbjct: 80 YYRRGAAYLAMGKFKDALKDFQQVKRLSPNDP-------DATRKLKECEKAVMKLKFEEA 132 Query: 766 LD-PKGANNQIKEAID 780 + P + E+ID Sbjct: 133 ISVPVSERRSVAESID 148 Score = 33.5 bits (75), Expect = 0.40, Method: Compositional matrix adjust. Identities = 22/81 (27%), Positives = 35/81 (43%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIY 645 AI + +AI+++ N A + EE A+ AI V+ R+ +Y G Y Sbjct: 28 AIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDASKAIEVDSRYSKGYYRRGAAY 87 Query: 646 YKQEKFSLAEMHFQKALDINP 666 KF A FQ+ ++P Sbjct: 88 LAMGKFKDALKDFQQVKRLSP 108 >6AF0-A nrPDB Length = 939 Score = 40.0 bits (92), Expect = 0.004, Method: Compositional matrix adjust. Identities = 38/142 (26%), Positives = 66/142 (46%), Gaps = 15/142 (10%) Query: 583 HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTE---ELDKALACFRNAIRVNPRHYNAWY 639 ++ A++FF +A+Q+DP AYA G L E + AL F +R + + + Sbjct: 721 YNRAVEFFDKALQLDPKNAYAAQ--GIAIALVEDRKDYKNALQIFIK-VRETIQDAHVYV 777 Query: 640 GLGMIYYKQEKFSLAEMHFQKALDINPQSS---VLLC------HIGVVQHALKKSEKALD 690 +G IY + +FS A ++ AL +++ ++ C + G + L + ALD Sbjct: 778 NMGHIYAELRQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYKMALD 837 Query: 691 TLNKAIVIDPKNPLCKFHRASV 712 KA+ + P KF+ A V Sbjct: 838 QAKKAVAVAPDQLHFKFNVAFV 859 Score = 39.7 bits (91), Expect = 0.005, Method: Compositional matrix adjust. Identities = 32/132 (24%), Positives = 66/132 (50%), Gaps = 4/132 (3%) Query: 687 KALDTLNKAIVIDPKNPLCKFHRASVLFANEK-YKSALQELEELKQIVPKESLVYFLIGK 745 +A++ +KA+ +DPKN A L + K YK+ALQ ++++ + +++ VY +G Sbjct: 723 RAVEFFDKALQLDPKNAYAAQGIAIALVEDRKDYKNALQIFIKVRETI-QDAHVYVNMGH 781 Query: 746 VYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQE 805 +Y +L Q A+ ++ A+ + K + I + + +L + M D++++ Sbjct: 782 IYAELRQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYKMALDQAKK 841 Query: 806 SSMTDADDTQLH 817 + D QLH Sbjct: 842 AVAVAPD--QLH 851 >6FO1-G nrPDB Length = 665 Score = 37.7 bits (86), Expect = 0.019, Method: Compositional matrix adjust. Identities = 24/110 (21%), Positives = 49/110 (44%) Query: 593 AIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFS 652 I VD A G+++ + D+A+ C+ + +P + Y++ +KF+ Sbjct: 125 GIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184 Query: 653 LAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKN 702 +AE A+ +N + G + AL+K E+A + + ++P N Sbjct: 185 VAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNN 234 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 24/93 (25%), Positives = 42/93 (45%) Query: 642 GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPK 701 G Y+KQ K+ A + K +D +P + VL + LKK A N A+ ++ Sbjct: 140 GNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRS 199 Query: 702 NPLCKFHRASVLFANEKYKSALQELEELKQIVP 734 R + FA +K + A ++ E + ++ P Sbjct: 200 YTKAYSRRGAARFALQKLEEAKKDYERVLELEP 232 Score = 30.4 bits (67), Expect = 3.6, Method: Compositional matrix adjust. Identities = 17/62 (27%), Positives = 31/62 (50%) Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 + ++ Q +++L G K ++A+D K + DP NP+ +RAS F +K+ Sbjct: 125 GIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFA 184 Query: 721 SA 722 A Sbjct: 185 VA 186 Score = 29.3 bits (64), Expect = 7.6, Method: Compositional matrix adjust. Identities = 38/192 (19%), Positives = 74/192 (38%), Gaps = 19/192 (9%) Query: 593 AIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFS 652 A+ ++ +Y AY+ G ++L++A + + + P ++ A L I + + Sbjct: 193 AVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKI---SQALA 249 Query: 653 LAEMHFQKALDI----------------NPQSSVLLCHIGVVQHALKKSEKALDTLNKAI 696 E + K DI N Q ++ G K E+A++ + I Sbjct: 250 SKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGI 309 Query: 697 VIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLA 756 D N L +RA +KY+ A ++ + + S + G LG+ + A Sbjct: 310 AADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEA 369 Query: 757 LMNFSWAMDLDP 768 +F + L+P Sbjct: 370 KQDFETVLLLEP 381 >1IHG-A nrPDB Length = 370 Score = 37.0 bits (84), Expect = 0.037, Method: Compositional matrix adjust. Identities = 26/126 (20%), Positives = 58/126 (46%), Gaps = 16/126 (12%) Query: 641 LGMIYYKQEKFSLAEMHFQKAL----------------DINPQSSVLLCHIGVVQHALKK 684 +G ++K + + +A + K L + P + + +IG + + Sbjct: 229 IGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMSD 288 Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 + A+D+ +A+ IDP N + RA ++Y AL +L++ ++I P++ + + Sbjct: 289 WQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAELL 348 Query: 745 KVYKKL 750 KV +K+ Sbjct: 349 KVKQKI 354 >5DSE-A nrPDB Length = 837 Score = 35.8 bits (81), Expect = 0.080, Method: Compositional matrix adjust. Identities = 20/91 (21%), Positives = 43/91 (47%) Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 +D+A + A+ ++P H + L +I ++ ++SLAE + A+ +N + + +G Sbjct: 740 MDEARRWYEEALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLG 799 Query: 677 VVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707 V A A + A+ ++ +P F Sbjct: 800 EVLQAQGNDAAATECFLTALELEASSPAVPF 830 Score = 30.0 bits (66), Expect = 4.1, Method: Compositional matrix adjust. Identities = 19/81 (23%), Positives = 36/81 (44%) Query: 619 KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVV 678 +A AC + A + P +N Y G I + A +++AL I+P + + ++ Sbjct: 708 EATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLALI 767 Query: 679 QHALKKSEKALDTLNKAIVID 699 H L + A L A+ ++ Sbjct: 768 LHQLGRYSLAEKILRDAVQVN 788 >2GW1-A nrPDB Length = 514 Score = 35.8 bits (81), Expect = 0.084, Method: Compositional matrix adjust. Identities = 31/145 (21%), Positives = 62/145 (42%), Gaps = 1/145 (0%) Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684 + AI + PR N++ + +I + + +F KAL ++ +S + H G + L+ Sbjct: 261 KKAIELFPR-VNSYIYMALIMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQN 319 Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 ++A +KA +DP+N A + + K+ E K+ P+ V Sbjct: 320 YDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFA 379 Query: 745 KVYKKLGQTHLALMNFSWAMDLDPK 769 ++ AL + A++L+ K Sbjct: 380 EILTDKNDFDKALKQYDLAIELENK 404 Score = 33.9 bits (76), Expect = 0.33, Method: Compositional matrix adjust. Identities = 26/113 (23%), Positives = 51/113 (45%), Gaps = 7/113 (6%) Query: 589 FFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQ 648 +F +A+++D N + Y G + + D+A F A ++P + + L + Y++ Sbjct: 292 YFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRE 351 Query: 649 EKFSLAEMHFQKALDINPQS-------SVLLCHIGVVQHALKKSEKALDTLNK 694 KF E F +A P++ + +L ALK+ + A++ NK Sbjct: 352 NKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENK 404 >5AEM-A nrPDB Length = 447 Score = 35.4 bits (80), Expect = 0.099, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 42/88 (47%), Gaps = 3/88 (3%) Query: 612 VLTEELD---KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668 +L+ +LD +A+ CF I +NP + + Y M+Y K + + A FQ+ NP Sbjct: 85 ILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARALDGFQRLYMYNPYD 144 Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAI 696 + +L + ++ + E +++ K Sbjct: 145 ANILRELAILYVDYDRIEDSIELYMKVF 172 >5ZYQ-A nrPDB Length = 320 Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust. Identities = 22/87 (25%), Positives = 47/87 (54%), Gaps = 3/87 (3%) Query: 576 CFSL-QREHDIAIKFFQRAIQVDPNYAYAYTL-LGHEFVLTEELDKALACFRNAIRVNPR 633 C S ++++ A+ ++++A++ +P L +GH FV +L+KA F A+ +N + Sbjct: 171 CISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSK 230 Query: 634 HYNAWYGLGMIYYKQEKFSLAE-MHFQ 659 A GL ++ ++ +E ++FQ Sbjct: 231 CVGALVGLAVLELNNKEADGSENLYFQ 257 >4ZLH-A nrPDB Length = 339 Score = 33.9 bits (76), Expect = 0.28, Method: Compositional matrix adjust. Identities = 33/135 (24%), Positives = 59/135 (43%), Gaps = 15/135 (11%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEG----MEIY-STTLWHLQKDVALSVLSKD 558 Q+GR Y Y +AE +F+++ ++R+ ++IY +T+ W DVA + Sbjct: 62 QLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVA-----ER 116 Query: 559 LTDMDKNSPEAWCAAGNC-FSLQR----EHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL 613 L + K+ A C +LQ + D A+ ++ D N A ++G F+ Sbjct: 117 LVKLGKDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMA 176 Query: 614 TEELDKALACFRNAI 628 E KA+ + I Sbjct: 177 KGEYAKAVESLQRVI 191 >1O1S-A nrPDB Length = 380 Score = 33.5 bits (75), Expect = 0.44, Method: Compositional matrix adjust. Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA-LDINPQSSVLLC 673 E ++A R+AI +N +Y W+ ++ +K EM++ A ++ P++ + Sbjct: 114 ERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWH 173 Query: 674 HIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729 H V+ LK + L+ + + D KN HR V+ + + LQ +++L Sbjct: 174 HRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQL 229 >2H6F-A nrPDB Length = 382 Score = 33.1 bits (74), Expect = 0.49, Method: Compositional matrix adjust. Identities = 32/135 (23%), Positives = 64/135 (47%), Gaps = 5/135 (3%) Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA-LDINPQSSVLLC 673 E ++A R+AI +N +Y W+ ++ +K EM++ A ++ P++ + Sbjct: 111 ERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYITAIIEEQPKNYQVWH 170 Query: 674 HIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE-LKQI 732 H V+ L+ + L+ + + D KN HR V+ + + + LQ +++ LK+ Sbjct: 171 HRRVLVEWLRDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFKLWDNELQYVDQLLKED 230 Query: 733 VPKESLV---YFLIG 744 V S+ YF+I Sbjct: 231 VRNNSVWNQRYFVIS 245 >4JA9-A nrPDB Length = 488 Score = 33.1 bits (74), Expect = 0.50, Method: Compositional matrix adjust. Identities = 20/92 (21%), Positives = 47/92 (51%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 Y+K + + A + +A+++NP +++ + + + AL +AI +D K Sbjct: 27 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 86 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKE 736 + RA+ A K+++AL++ E + ++ P + Sbjct: 87 GYYRRAASNMALGKFRAALRDYETVVKVKPND 118 >5FZQ-A nrPDB Length = 131 Score = 33.1 bits (74), Expect = 0.56, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 48/100 (48%) Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 NS + N + + + + AIK+ ++A+ +DPN + L + + ++A+ Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 R A+ ++P + L ++ ++ K A + +KA+ + Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 22/110 (20%), Positives = 52/110 (47%), Gaps = 1/110 (0%) Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 ++A+ R A+ ++P + L + ++ K A + +KA+ ++P + L ++ V Sbjct: 22 EEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLAV 81 Query: 678 VQHALKKSEKALDTLNKAI-VIDPKNPLCKFHRASVLFANEKYKSALQEL 726 + K+E+A+ + KA+ +ID H+ + + +Q+L Sbjct: 82 LLAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAAARRKSRLMRKVQKL 131 Score = 28.9 bits (63), Expect = 9.7, Method: Composition-based stats. Identities = 22/98 (22%), Positives = 50/98 (51%), Gaps = 2/98 (2%) Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700 L + ++ K A + +KA+ ++P + L ++ + K+E+A+ + KA+ +DP Sbjct: 11 LANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDP 70 Query: 701 KNPLCKFHRASVLFANE-KYKSALQELEELKQIVPKES 737 N + +VL A E K + A++ + + ++ K + Sbjct: 71 NN-IKTLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAA 107 >2BED-A nrPDB Length = 313 Score = 32.3 bits (72), Expect = 0.76, Method: Compositional matrix adjust. Identities = 27/116 (23%), Positives = 54/116 (46%), Gaps = 1/116 (0%) Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA-LDINPQSSVLLC 673 E ++A R+AI +N +Y W+ ++ +K EM++ A ++ P++ + Sbjct: 58 ERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEMNYITAIIEEQPKNYQVWH 117 Query: 674 HIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729 H V+ LK + L+ + + D KN HR V+ + + LQ +++L Sbjct: 118 HRRVLVEWLKDPSQELEFIADILNQDAKNYHAWQHRQWVIQEFRLWDNELQYVDQL 173 >4UZY-A nrPDB Length = 651 Score = 32.3 bits (72), Expect = 0.78, Method: Compositional matrix adjust. Identities = 41/189 (21%), Positives = 73/189 (38%), Gaps = 31/189 (16%) Query: 539 YSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAA---GNCFSLQREHDIAIKFFQRAIQ 595 Y+ T++ L K+ + + L +N PE+ A G C+ ++D+A + +++ + Sbjct: 20 YTQTIYTLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVT 79 Query: 596 VDPN-----YAYAYTLL----------------GHEFVLTE-------ELDKALACFRNA 627 + P+ YA +L GH+ +T E D C R Sbjct: 80 LYPSNEDYKLYYAQSLYKGGMYPEASKAVVKVEGHQKAVTTLLVACSYEQDDLTGCRRQL 139 Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 + P + G I +K+ KF A F A+ LL +I + + K+ Sbjct: 140 DKCAPEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIALCYYKTKQFGP 199 Query: 688 ALDTLNKAI 696 AL L + I Sbjct: 200 ALKHLAEII 208 >1A17-A nrPDB Length = 166 Score = 32.3 bits (72), Expect = 0.83, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 47/92 (51%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 Y+K + + A + +A+++NP +++ + + + AL +AI +D K Sbjct: 23 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 82 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKE 736 + RA+ A K+++AL++ E + ++ P + Sbjct: 83 GYYRRAASNMALGKFRAALRDYETVVKVKPHD 114 >6AHD-N nrPDB Length = 941 Score = 32.3 bits (72), Expect = 0.86, Method: Compositional matrix adjust. Identities = 32/139 (23%), Positives = 55/139 (39%), Gaps = 1/139 (0%) Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 NS E W AA S E++ A + +A P + E+V + + A Sbjct: 640 NSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSVKLEWV-QDNIRAAQDLC 698 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684 A+R W G I ++E A + + L P S+ L + ++ + + Sbjct: 699 EEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLLSRLEEKIGQ 758 Query: 685 SEKALDTLNKAIVIDPKNP 703 +A L K+ + +PKNP Sbjct: 759 LTRARAILEKSRLKNPKNP 777 >5OMP-A nrPDB Length = 462 Score = 32.3 bits (72), Expect = 0.95, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 36/82 (43%) Query: 603 AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662 A+ L ++ E KA+ C A+ ++ + Y G +F A+ F+K L Sbjct: 324 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVL 383 Query: 663 DINPQSSVLLCHIGVVQHALKK 684 ++NPQ+ I + Q K+ Sbjct: 384 EVNPQNKAARLQISMCQKKAKE 405 Score = 30.0 bits (66), Expect = 4.3, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 13/121 (10%) Query: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647 K+ Q IQ Y + L E+ L+E+ KA F A A+ L M Y K Sbjct: 288 KYMQAVIQ----YGKIVSWLEMEYGLSEKESKASESFLLA---------AFLNLAMCYLK 334 Query: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707 +++ A KAL ++ + L G Q + + E A K + ++P+N + Sbjct: 335 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 394 Query: 708 H 708 Sbjct: 395 Q 395 >5NNP-A nrPDB Length = 745 Score = 32.0 bits (71), Expect = 1.00, Method: Compositional matrix adjust. Identities = 15/62 (24%), Positives = 33/62 (53%) Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 ++A A + A+ ++ + Y W+ G++Y + F A ++ AL + P+S + + V Sbjct: 61 EEAFALAKEALTIDMKSYICWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAV 120 Query: 678 VQ 679 +Q Sbjct: 121 LQ 122 >4HOQ-A nrPDB Length = 482 Score = 32.0 bits (71), Expect = 1.0, Method: Compositional matrix adjust. Identities = 38/149 (25%), Positives = 65/149 (43%), Gaps = 35/149 (23%) Query: 586 AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV--------NPRHYNA 637 AI F+ A++ D +A+AYT L + + + A FR A+R+ + HY+ Sbjct: 323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLENITDDHKHQIHYH- 381 Query: 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQS-------SVL-------LCH--------- 674 YG ++++ + + A H+ +AL + +S S L LCH Sbjct: 382 -YGRFQEFHRKSE-NTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLS 439 Query: 675 -IGVVQHALKKSEKALDTLNKAIVIDPKN 702 +G V + +A + KA IDP+N Sbjct: 440 ALGFVYKLEGEKRQAAEYYEKAQKIDPEN 468 >1QZ2-A nrPDB Length = 336 Score = 30.8 bits (68), Expect = 2.3, Method: Compositional matrix adjust. Identities = 23/113 (20%), Positives = 48/113 (42%), Gaps = 25/113 (22%) Query: 642 GMIYYKQEKFSLAEMHFQK--------------------ALDINPQSSVLLCHIGVVQHA 681 G +Y+K+ K+ A + ++K AL + ++ +CH+ Sbjct: 154 GTVYFKEGKYKQALLQYKKIVSWLEYESSFSNEEAQKAQALRLASHLNLAMCHL-----K 208 Query: 682 LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVP 734 L+ A+++ NKA+ +D N F R A ++ A + +++ Q+ P Sbjct: 209 LQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQKVLQLYP 261 >1KT1-A nrPDB Length = 457 Score = 30.8 bits (68), Expect = 2.8, Method: Compositional matrix adjust. Identities = 20/82 (24%), Positives = 36/82 (43%) Query: 603 AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662 A+ L ++ E KA+ C A+ ++ + Y G +F A+ F+K L Sbjct: 319 AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVL 378 Query: 663 DINPQSSVLLCHIGVVQHALKK 684 ++NPQ+ I + Q K+ Sbjct: 379 EVNPQNKAARLQIFMCQKKAKE 400 Score = 29.3 bits (64), Expect = 7.2, Method: Compositional matrix adjust. Identities = 30/121 (24%), Positives = 49/121 (40%), Gaps = 13/121 (10%) Query: 588 KFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYK 647 K+ Q IQ Y + L E+ L+E+ KA F A A+ L M Y K Sbjct: 283 KYVQAVIQ----YGKIVSWLEMEYGLSEKESKASESFLLA---------AFLNLAMCYLK 329 Query: 648 QEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKF 707 +++ A KAL ++ + L G Q + + E A K + ++P+N + Sbjct: 330 LREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFEKVLEVNPQNKAARL 389 Query: 708 H 708 Sbjct: 390 Q 390 >5WVI-K nrPDB Length = 428 Score = 30.8 bits (68), Expect = 2.8, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 46/128 (35%), Gaps = 30/128 (23%) Query: 246 PLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTP 305 P GTG ++L K V N K + G ++ Y Sbjct: 214 PPGTGKTMLVKAVANSTKAAFIRVNG-----------------------SEFVHKYLGEG 250 Query: 306 P-----VIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQ--TQSSGPQTST 358 P V + APS + + TK +Q+G+ REV IL + TQ G ST Sbjct: 251 PRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQST 310 Query: 359 TPQVLSPT 366 +V+ T Sbjct: 311 NVKVIMAT 318 >2C2L-A nrPDB Length = 281 Score = 30.4 bits (67), Expect = 2.9, Method: Compositional matrix adjust. Identities = 23/88 (26%), Positives = 43/88 (48%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 GN + R++ A + RAI +P A YT ++ ++ ++ALA R A+ ++ + Sbjct: 11 GNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQ 70 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKA 661 A + LG + E + A + Q+A Sbjct: 71 SVKAHFFLGQCQLEMESYDEAIANLQRA 98 >6EF1-K nrPDB Length = 276 Score = 30.4 bits (67), Expect = 3.7, Method: Compositional matrix adjust. Identities = 32/128 (25%), Positives = 46/128 (35%), Gaps = 30/128 (23%) Query: 246 PLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTP 305 P GTG ++L K V N K + G ++ Y Sbjct: 62 PPGTGKTMLVKAVANSTKAAFIRVNG-----------------------SEFVHKYLGEG 98 Query: 306 P-----VIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQ--TQSSGPQTST 358 P V + APS + + TK +Q+G+ REV IL + TQ G ST Sbjct: 99 PRMVRDVFRLARENAPSIIFIDEVDSIATKRFDAQTGSDREVQRILIELLTQMDGFDQST 158 Query: 359 TPQVLSPT 366 +V+ T Sbjct: 159 NVKVIMAT 166 >5VHO-B nrPDB Length = 267 Score = 30.0 bits (66), Expect = 4.2, Method: Composition-based stats. Identities = 45/200 (22%), Positives = 77/200 (38%), Gaps = 37/200 (18%) Query: 246 PLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTP 305 P GTG ++L+K V N+ + G + GDG L Sbjct: 61 PPGTGKTLLAKAVANQTSATFLRVVGSELIQKYL-------------GDGPKL-----VR 102 Query: 306 PVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQ--TQSSGPQTSTTPQVL 363 + V APS + I GTK S SG RE+ + + Q G + +V+ Sbjct: 103 ELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVI 162 Query: 364 SPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQPNI 423 T +R+ T D + + K++FP +P+ KTK + + ++ + Sbjct: 163 MAT------------NRIETLDPALIRPGRIDRKIEFP--LPDEKTKKRIFQIHTSRMTL 208 Query: 424 NDSLEITKLDSSIISEGKIS 443 D + LD I+++ +S Sbjct: 209 ADDV---TLDDLIMAKDDLS 225 >1HH8-A nrPDB Length = 213 Score = 30.0 bits (66), Expect = 4.7, Method: Compositional matrix adjust. Identities = 22/85 (25%), Positives = 42/85 (49%), Gaps = 2/85 (2%) Query: 665 NPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQ 724 +P S + +IG + LK +A ++I D + F R + + EKY A++ Sbjct: 34 DPHSRICF-NIGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIK 92 Query: 725 ELEE-LKQIVPKESLVYFLIGKVYK 748 +L+E L Q+ + + Y ++G +K Sbjct: 93 DLKEALIQLRGNQLIDYKILGLQFK 117 Score = 29.3 bits (64), Expect = 6.7, Method: Compositional matrix adjust. Identities = 15/56 (26%), Positives = 30/56 (53%) Query: 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662 +G + + + + +A F +I + A++ GM+YY+ EK+ LA ++AL Sbjct: 43 IGCMYTILKNMTEAEKAFTRSINRDKHLAVAYFQRGMLYYQTEKYDLAIKDLKEAL 98 >2WAU-A nrPDB Length = 302 Score = 29.6 bits (65), Expect = 5.0, Method: Compositional matrix adjust. Identities = 15/51 (29%), Positives = 28/51 (54%), Gaps = 10/51 (19%) Query: 692 LNKAIVIDPK----------NPLCKFHRASVLFANEKYKSALQELEELKQI 732 +NK +++ P+ + +CK+ R LF + Y SA+ E+E LK++ Sbjct: 30 INKGVLLPPRRKNLFLKIDESDICKYKRDPKLFKDFIYSSAISEVERLKKV 80 >5VFP-B nrPDB Length = 389 Score = 29.6 bits (65), Expect = 5.2, Method: Compositional matrix adjust. Identities = 40/169 (23%), Positives = 63/169 (37%), Gaps = 34/169 (20%) Query: 246 PLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTP 305 P GTG ++L+K V N+ + G + GDG L Sbjct: 176 PPGTGKTLLAKAVANQTSATFLRVVGSELIQKYL-------------GDGPKL-----VR 217 Query: 306 PVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQ--TQSSGPQTSTTPQVL 363 + V APS + I GTK S SG RE+ + + Q G + +V+ Sbjct: 218 ELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVI 277 Query: 364 SPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSK 412 T +R+ T D + + K++FP +P+ KTK + Sbjct: 278 MAT------------NRIETLDPALIRPGRIDRKIEFP--LPDEKTKKR 312 >5UDI-A nrPDB Length = 479 Score = 29.3 bits (64), Expect = 6.5, Method: Compositional matrix adjust. Identities = 45/181 (24%), Positives = 73/181 (40%), Gaps = 35/181 (19%) Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH--------FQKALDINPQSS 669 ++A ACF + V+P + + G + Y+ + F LA + ++A+ +NP + Sbjct: 159 ERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNG 218 Query: 670 VL-------LCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR--ASVLFANEKYK 720 + L G K E+AL ++ + KF+R SV A E K Sbjct: 219 YIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYV--FRYAAKFYRRKGSVDKALELLK 276 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 ALQE P L++ IG YK ++ A P+G N +E +D Sbjct: 277 KALQE-------TPTSVLLHHQIGLCYKA------QMIQIKEATKGQPRGQN---REKLD 320 Query: 781 K 781 K Sbjct: 321 K 321 >5VHF-B nrPDB Length = 340 Score = 29.3 bits (64), Expect = 6.8, Method: Compositional matrix adjust. Identities = 43/169 (25%), Positives = 66/169 (39%), Gaps = 34/169 (20%) Query: 246 PLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQNYTNTP 305 P GTG ++L+K V N+ T + L S L + GDG L Sbjct: 135 PPGTGKTLLAKAVANQ--TSATFL--RVVGSELIQKY---------LGDGPKL-----VR 176 Query: 306 PVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQ--TQSSGPQTSTTPQVL 363 + V APS + I GTK S SG RE+ + + Q G + +V+ Sbjct: 177 ELFRVAEEHAPSIVFIDEIDAIGTKRYDSNSGGEREIQRTMLELLNQLDGFDSRGDVKVI 236 Query: 364 SPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSK 412 T +R+ T D + + K++FP +P+ KTK + Sbjct: 237 MAT------------NRIETLDPALIRPGRIDRKIEFP--LPDEKTKKR 271 >4AR2-A nrPDB Length = 509 Score = 29.3 bits (64), Expect = 7.1, Method: Compositional matrix adjust. Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 3/50 (6%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEG---MEIYSTTLWHLQ 547 V C + Y+ L + MQ F R++ NY V G M ++S + ++ Q Sbjct: 370 VTCGAEQVYWSLPDMMQDPVTFRSTRQVNNYPVVGAELMPVFSKSFYNEQ 419 >4GYO-A nrPDB Length = 373 Score = 28.9 bits (63), Expect = 8.7, Method: Compositional matrix adjust. Identities = 17/66 (25%), Positives = 37/66 (56%), Gaps = 1/66 (1%) Query: 704 LCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763 + +F + + + A + YK A ++LE ++ + K + F + +VY + QT+ ++ S A Sbjct: 107 MYEFKQKNFILAIDHYKHAEEKLEYVEDEIEKAEFL-FKVAEVYYHIKQTYFSMNYASQA 165 Query: 764 MDLDPK 769 +D+ K Sbjct: 166 LDIYTK 171 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5G04-F nrPDB 1530 0.0 5G04-X nrPDB 330 2e-90 5KHR-J nrPDB 285 4e-77 1W3B-A nrPDB 265 5e-71 5G05-C nrPDB 253 2e-67 5LVV-A nrPDB 176 3e-44 5A01-A nrPDB 174 1e-43 6B85-J nrPDB 146 6e-35 5JJT-A nrPDB 126 5e-29 Sequences not found previously or not previously below threshold: 5NNP-A nrPDB 84 3e-16 2GW1-A nrPDB 83 7e-16 6FO1-G nrPDB 81 2e-15 4JA9-A nrPDB 74 2e-13 1A17-A nrPDB 74 3e-13 2Y4T-A nrPDB 71 2e-12 5FZQ-A nrPDB 70 4e-12 1QZ2-A nrPDB 66 7e-11 5AEM-A nrPDB 63 4e-10 4HOQ-A nrPDB 63 5e-10 5DSE-A nrPDB 61 2e-09 6C95-A nrPDB 61 2e-09 6AF0-A nrPDB 61 3e-09 6AHD-N nrPDB 61 3e-09 5XJC-J nrPDB 59 1e-08 4UZY-A nrPDB 58 2e-08 5OJF-A nrPDB 58 2e-08 5UDI-A nrPDB 57 3e-08 5WQL-B nrPDB 57 4e-08 3NF1-A nrPDB 57 4e-08 4JHR-A nrPDB 56 6e-08 4ABN-A nrPDB 56 6e-08 3JCM-G nrPDB 55 1e-07 2C2L-A nrPDB 55 1e-07 5OJ8-A nrPDB 55 2e-07 5ZYQ-A nrPDB 55 2e-07 4G1T-A nrPDB 54 2e-07 3ZFW-A nrPDB 54 2e-07 4ZLH-A nrPDB 53 5e-07 1IHG-A nrPDB 53 6e-07 6FUZ-A nrPDB 53 6e-07 4I9E-A nrPDB 52 8e-07 5JZ6-A nrPDB 51 2e-06 5O09-1C nrPDB 50 4e-06 2IF4-A nrPDB 49 6e-06 6FRK-r nrPDB 48 1e-05 6ICZ-I nrPDB 44 2e-04 4HOU-A nrPDB 44 2e-04 3J98-H nrPDB 44 3e-04 5NLG-A nrPDB 44 3e-04 5C9S-B nrPDB 44 3e-04 5OMP-A nrPDB 44 3e-04 4GYO-A nrPDB 43 5e-04 1KT1-A nrPDB 43 5e-04 5MGX-E nrPDB 41 0.002 4I2W-A nrPDB 41 0.002 5LJ5-S nrPDB 40 0.003 2IFU-A nrPDB 40 0.005 5GMK-d nrPDB 39 0.013 3QDN-A nrPDB 38 0.015 5BT1-A nrPDB 38 0.018 5JHE-A nrPDB 38 0.019 5OQL-E nrPDB 38 0.020 5IC8-A nrPDB 38 0.020 6G70-A nrPDB 37 0.031 3LVG-A nrPDB 37 0.034 1B89-A nrPDB 37 0.034 5ZYP-A nrPDB 37 0.043 4D18-C nrPDB 36 0.048 4CGU-A nrPDB 36 0.056 6MFV-A nrPDB 36 0.099 3JB9-R nrPDB 34 0.20 3QOU-A nrPDB 34 0.28 1ZU2-A nrPDB 34 0.32 3ZN3-A nrPDB 34 0.38 4I1A-A nrPDB 33 0.69 4HNX-A nrPDB 32 0.89 6N3Q-F nrPDB 32 0.96 4JCS-A nrPDB 32 1.0 4MBG-A nrPDB 32 1.2 2BED-A nrPDB 31 2.6 1O1S-A nrPDB 31 2.6 3U48-A nrPDB 31 2.9 4IN3-B nrPDB 31 3.1 3LY9-A nrPDB 31 3.3 2H6F-A nrPDB 30 4.6 6QGL-A nrPDB 29 6.8 >5G04-F nrPDB Length = 824 Score = 1530 bits (3960), Expect = 0.0, Method: Composition-based stats. Identities = 824/824 (100%), Positives = 824/824 (100%) Query: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL Sbjct: 1 MTVLQEPVQAAIWQALNHYAYRDAVFLAERLYAEVHSEEALFLLATCYYRSGKAYKAYRL 60 Query: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL Sbjct: 61 LKGHSCTTPQCKYLLAKCCVDLSKLAEGEQILSGGVFNKQKSHDDIVTEFGDSACFTLSL 120 Query: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL Sbjct: 121 LGHVYCKTDRLAKGSECYQKSLSLNPFLWSPFESLCEIGEKPDPDQTFKFTSLQNFSNCL 180 Query: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI Sbjct: 181 PNSCTTQVPNHSLSHRQPETVLTETPQDTIELNRLNLESSNSKYSLNTDSSVSYIDSAVI 240 Query: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN Sbjct: 241 SPDTVPLGTGTSILSKQVQNKPKTGRSLLGGPAALSPLTPSFGILPLETPSPGDGSYLQN 300 Query: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP Sbjct: 301 YTNTPPVIDVPSTGAPSKKSVARIGQTGTKSVFSQSGNSREVTPILAQTQSSGPQTSTTP 360 Query: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ Sbjct: 361 QVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPPKIPNRKTKSKTNKGGITQ 420 Query: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN Sbjct: 421 PNINDSLEITKLDSSIISEGKISTITPQIQAFNLQKAAAEGLMSLLREMGKGYLALCSYN 480 Query: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS Sbjct: 481 CKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYS 540 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY Sbjct: 541 TTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY 600 Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK Sbjct: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK Sbjct: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID Sbjct: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 Query: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF Sbjct: 781 KRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDEF 824 >5G04-X nrPDB Length = 599 Score = 330 bits (845), Expect = 2e-90, Method: Composition-based stats. Identities = 99/496 (19%), Positives = 188/496 (37%), Gaps = 34/496 (6%) Query: 343 TPILAQTQSSGPQTSTTPQVLSPTITSPPNALPRRSSRLFTSDSSTTKENSKKLKMKFPP 402 T L Q ++ + P + T LP + T K + Sbjct: 101 TMALQQKKALSKTSKVRPSTGNSASTPQSQCLPSEIEVKYKMAECYTMLKQDKDAIAILD 160 Query: 403 KIPNRKTKSKTN--------KGGITQPNINDSLEITK-----LDSSIISEGKISTITPQI 449 IP+R+ K N K G +P++ E+ + LD+ I+ +S ++ Sbjct: 161 GIPSRQRTPKINMMLANLYKKAGQERPSVTSYKEVLRQCPLALDA-ILGLLSLSVKGAEV 219 Query: 450 QAFNLQKAAAEGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHY---NTGWVLCQIG 506 + + + L K Y + + + AI+ + L N +L + Sbjct: 220 ASMTMNVIQTVPNLDWLSVWIKAYAFVHTGDNSRAISTICSLEKKSLLRDNVD-LLGSLA 278 Query: 507 RAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNS 566 YF + + F + + ++ Y ++GM++Y L + + L L ++ Sbjct: 279 DLYFRAGDNKNSVLKFEQAQMLDPYLIKGMDVYGYLLAREGRLEDVENLGCRLFNISDQH 338 Query: 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626 E W +G + + A+ +AIQ++ N A L G + +A+ FR Sbjct: 339 AEPWVVSGCHSFYSKRYSRALYLGAKAIQLNSNSVQALLLKGAALRNMGRVQEAIIHFRE 398 Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGVVQHALK 683 AIR+ P + + GL Y A + + K L N Q+ LL + + + Sbjct: 399 AIRLAPCRLDCYEGLIECYLASNSIREAMVMANNVYKTLGANAQTLTLLATVCLEDPVTQ 458 Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES--LVYF 741 EKA L+KA+ P +A +L +KY+ + L+ + +S +++ Sbjct: 459 --EKAKTLLDKALTQRPDYIKAVVKKAELLSREQKYEDG---IALLRNALANQSDCVLHR 513 Query: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPI--TQEEQIMG 799 ++G + + A+ +S A+ LDP N K + + +E P TQEE + Sbjct: 514 ILGDFLVAVNEYQEAMDQYSIALSLDP----NDQKSLEGMQKMEKEESPTDATQEEDVDD 569 Query: 800 TDESQESSMTDADDTQ 815 + S E + D++ Sbjct: 570 MEGSGEEGDLEGSDSE 585 >5KHR-J nrPDB Length = 620 Score = 285 bits (730), Expect = 4e-77, Method: Composition-based stats. Identities = 77/316 (24%), Positives = 134/316 (42%), Gaps = 32/316 (10%) Query: 487 ILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHL 546 ++S H+YN + +C ++ S V + + + ++ TL L Sbjct: 234 VVSLAERHYYNCDFKMCY---------------KLTSVVMEKDPFHASCLPVHIGTLVEL 278 Query: 547 QKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREH--DIAIKFFQRAIQVDPNYAYAY 604 K L LS L D+ ++P +W A G C+ L H + A ++ +A ++ Y A+ Sbjct: 279 NKANELFYLSHKLVDLYPSNPVSWFAVG-CYYLMVGHKNEHARRYLSKATTLEKTYGPAW 337 Query: 605 TLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 GH F + E D+A+A + A ++ + +G+ Y LAE F +AL I Sbjct: 338 IAYGHSFAVESEHDQAMAAYFTAAQLMKGCHLPMLYIGLEYGLTNNSKLAERFFSQALSI 397 Query: 665 NPQSSVLLCHIGVVQH---ALKKSEKA-LDTLNK------AIVIDPKNPLCKFHRASVLF 714 P+ ++ +GVV K +EK LD L K + +D PL + V Sbjct: 398 APEDPFVMHEVGVVAFQNGEWKTAEKWFLDALEKIKAIGNEVTVDKWEPLLN-NLGHVCR 456 Query: 715 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL--DPKGAN 772 +KY AL + ++P+ + Y IG ++ +G A+ F A+ L D + Sbjct: 457 KLKKYAEALDYHRQALVLIPQNASTYSAIGYIHSLMGNFENAVDYFHTALGLRRDDTFSV 516 Query: 773 NQIKEAIDKRYLPDDE 788 + I+ Y+ D E Sbjct: 517 TMLGHCIEM-YIGDSE 531 >1W3B-A nrPDB Length = 388 Score = 265 bits (677), Expect = 5e-71, Method: Composition-based stats. Identities = 62/307 (20%), Positives = 121/307 (39%), Gaps = 10/307 (3%) Query: 482 KEAINILSHLPSHHYNTGWVLCQI--GRAYFELSEYMQAERIFSEVRRIENYRVEGMEIY 539 +EAI H ++ I A + A + + + Sbjct: 84 QEAIEHYRHALR--LKPDFIDGYINLAAALVAAGDMEGAVQAYVSALQYNPDLYCVRSDL 141 Query: 540 STTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPN 599 L L + + N AW G F+ Q E +AI F++A+ +DPN Sbjct: 142 GNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQGEIWLAIHHFEKAVTLDPN 201 Query: 600 YAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQ 659 + AY LG+ D+A+A + A+ ++P H L +YY+Q LA ++ Sbjct: 202 FLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNLACVYYEQGLIDLAIDTYR 261 Query: 660 KALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKY 719 +A+++ P C++ +A D N A+ + P + + A++ Sbjct: 262 RAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPTHADSLNNLANIKREQGNI 321 Query: 720 KSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGAN------N 773 + A++ + ++ P+ + + + V ++ G+ ALM++ A+ + P A+ N Sbjct: 322 EEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGN 381 Query: 774 QIKEAID 780 +KE D Sbjct: 382 TLKEMQD 388 Score = 170 bits (430), Expect = 2e-42, Method: Composition-based stats. Identities = 59/322 (18%), Positives = 123/322 (38%), Gaps = 34/322 (10%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMD 563 ++ ++ ++ AER ++ R E + + S+ + ++ + S + Sbjct: 4 ELAHREYQAGDFEAAERHCMQLWRQEPDNTGVLLLLSSIHFQCRRLDRSAHFSTLAIKQN 63 Query: 564 KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLL---------------- 607 EA+ GN + + + AI+ ++ A+++ P++ Y L Sbjct: 64 PLLAEAYSNLGNVYKERGQLQEAIEHYRHALRLKPDFIDGYINLAAALVAAGDMEGAVQA 123 Query: 608 ------------------GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 649 G+ L++A AC+ AI P AW LG ++ Q Sbjct: 124 YVSALQYNPDLYCVRSDLGNLLKALGRLEEAKACYLKAIETQPNFAVAWSNLGCVFNAQG 183 Query: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR 709 + LA HF+KA+ ++P ++G V + ++A+ +A+ + P + + + Sbjct: 184 EIWLAIHHFEKAVTLDPNFLDAYINLGNVLKEARIFDRAVAAYLRALSLSPNHAVVHGNL 243 Query: 710 ASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 A V + A+ ++ P Y + K+ G A ++ A+ L P Sbjct: 244 ACVYYEQGLIDLAIDTYRRAIELQPHFPDAYCNLANALKEKGSVAEAEDCYNTALRLCPT 303 Query: 770 GANNQIKEAIDKRYLPDDEEPI 791 A++ A KR + EE + Sbjct: 304 HADSLNNLANIKREQGNIEEAV 325 >5G05-C nrPDB Length = 597 Score = 253 bits (647), Expect = 2e-67, Method: Composition-based stats. Identities = 75/307 (24%), Positives = 144/307 (46%), Gaps = 13/307 (4%) Query: 498 TGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSK 557 + +++ QI AY + + +A IF+E+R+ + YR+E M+ +S L+ LS L+ Sbjct: 262 SSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSMKSELSYLAH 321 Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 +L ++DK E C GN +SL+ +H+ A +FQRA++++P Y A+TL+GHE++ + Sbjct: 322 NLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRYLGAWTLMGHEYMEMKNT 381 Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 A+ +R+AI VN R Y AWYGLG Y + ++++A + P S +L +G Sbjct: 382 SAAIQAYRHAIEVNKRDYRAWYGLGQTYEILKMPFYCLYYYRRAHQLRPNDSRMLVALGE 441 Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSA----LQELEELKQI- 732 L + +A +A + + A + + + A ++ ++++ Sbjct: 442 CYEKLNQLVEAKKCYWRAYAVGDVEKMALVKLAKLHEQLTESEQAAQCYIKYIQDIYSCG 501 Query: 733 ----VPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ--IKEAIDKRYLPD 786 +ES + + + Y K A + + +++ + R Sbjct: 502 EIVEHLEESTAFRYLAQYYFKCKLWDEASTCAQKCCAFNDTREEGKALLRQILQLRNQG- 560 Query: 787 DEEPITQ 793 E P T+ Sbjct: 561 -ETPTTE 566 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 55/292 (18%), Positives = 99/292 (33%), Gaps = 42/292 (14%) Query: 505 IGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDK 564 + +AYF++ EY +A + Y + +YS L +K + +D Sbjct: 89 LAKAYFDVKEYDRAAHFLHGCNSKKAYF---LYMYSRYLSGEKKKDDET--------VDS 137 Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 P N + +++ K R + + L G + + +A+ F Sbjct: 138 LGPLEKGQVKNEALRELRVELSKKHQAREL-----DGFGLYLYGVVLRKLDLVKEAIDVF 192 Query: 625 RNAIRVNPRHYNAWYG-------------------------LGMIYYKQEKFSLAEMHFQ 659 A V P H+ AW L IY + + A +Q Sbjct: 193 VEATHVLPLHWGAWLELCNLITDKEMLKFLSLPDTWMKEFFLAHIYTELQLIEEALQKYQ 252 Query: 660 KALDIN-PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEK 718 +D+ +SS ++ I V H ++ +KAL N+ DP +++L+ Sbjct: 253 NLIDVGFSKSSYIVSQIAVAYHNIRDIDKALSIFNELRKQDPYRIENMDTFSNLLYVRSM 312 Query: 719 YKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKG 770 L +I +IG Y Q A + F A+ L+P+ Sbjct: 313 KSELSYLAHNLCEIDKYRVETCCVIGNYYSLRSQHEKAALYFQRALKLNPRY 364 >5LVV-A nrPDB Length = 749 Score = 176 bits (446), Expect = 3e-44, Method: Composition-based stats. Identities = 37/236 (15%), Positives = 77/236 (32%), Gaps = 41/236 (17%) Query: 532 RVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQ 591 + + + L + ++ A + Q + A+ ++ Sbjct: 29 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 88 Query: 592 RAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651 AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A L I+ Sbjct: 89 EAIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 148 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRAS 711 A ++ AL + P C++ H Sbjct: 149 PEAIASYRTALKLKPDFPDAYCNLA-------------------------------HCLQ 177 Query: 712 VLFANEKYKSALQEL----------EELKQIVPKESLVYFLIGKVYKKLGQTHLAL 757 ++ Y +++L L + P S++Y L K + + H L Sbjct: 178 IVCDWTDYDERMKKLVSIVADQLEKNRLPSVHPHHSMLYPLSHGFRKAIAERHGNL 233 Score = 82.9 bits (203), Expect = 5e-16, Method: Composition-based stats. Identities = 17/107 (15%), Positives = 44/107 (41%), Gaps = 9/107 (8%) Query: 685 SEKALDTLNKAIVID---PKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF 741 A T ++ + + + A++ + A++ + ++ P+ + + Sbjct: 9 YSSAQSTSKTSVTLSLGGGTHADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHS 68 Query: 742 LIGKVYKKLGQTHLALMNFSWAMDLDPKGAN------NQIKEAIDKR 782 + V ++ G+ ALM++ A+ + P A+ N +KE D + Sbjct: 69 NLASVLQQQGKLQEALMHYKEAIRISPTFADAYSNMGNTLKEMQDVQ 115 Score = 79.1 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 26/146 (17%), Positives = 59/146 (40%) Query: 502 LCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTD 561 L + E +A R++ + + ++ L K + K+ Sbjct: 33 LNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKEAIR 92 Query: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621 + +A+ GN ++ A++ + RAIQ++P +A A++ L + + +A+ Sbjct: 93 ISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAI 152 Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYK 647 A +R A+++ P +A+ L Sbjct: 153 ASYRTALKLKPDFPDAYCNLAHCLQI 178 Score = 77.5 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 53/123 (43%) Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEE 728 + L ++ ++ E+A+ KA+ + P+ + ASVL K + AL +E Sbjct: 30 ADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYKE 89 Query: 729 LKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDE 788 +I P + Y +G K++ AL ++ A+ ++P A+ A + + Sbjct: 90 AIRISPTFADAYSNMGNTLKEMQDVQGALQCYTRAIQINPAFADAHSNLASIHKDSGNIP 149 Query: 789 EPI 791 E I Sbjct: 150 EAI 152 Score = 30.2 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 7/61 (11%), Positives = 23/61 (37%) Query: 736 ESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEE 795 + + + ++ G A+ + A+++ P+ A A + +E + + Sbjct: 29 HADSLNNLANIKREQGNIEEAVRLYRKALEVFPEFAAAHSNLASVLQQQGKLQEALMHYK 88 Query: 796 Q 796 + Sbjct: 89 E 89 >5A01-A nrPDB Length = 710 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 37/236 (15%), Positives = 77/236 (32%), Gaps = 41/236 (17%) Query: 532 RVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQ 591 + + + + L ++ + A + Q + A+ ++ Sbjct: 6 HADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYK 65 Query: 592 RAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651 AI++ P +A AY+ +G+ +++ AL C+ AI++NP +A L I+ Sbjct: 66 EAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNI 125 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRAS 711 A ++ AL + P C++ H Sbjct: 126 PEAIQSYRTALKLKPDFPDAYCNLA-------------------------------HCLQ 154 Query: 712 VLFANEKYKSALQEL----------EELKQIVPKESLVYFLIGKVYKKLGQTHLAL 757 ++ Y +++L L + P S++Y L K + H L Sbjct: 155 IVCDWTDYDIRMKKLVSIVTEQLEKNRLPSVHPHHSMLYPLTHDCRKAIAARHANL 210 Score = 94.1 bits (232), Expect = 2e-19, Method: Composition-based stats. Identities = 30/140 (21%), Positives = 55/140 (39%) Query: 633 RHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTL 692 H ++ L I +Q A + KAL++ P + ++ V K ++AL Sbjct: 5 NHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHY 64 Query: 693 NKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQ 752 +AI I P + + L + ALQ QI P + + + ++K G Sbjct: 65 KEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGN 124 Query: 753 THLALMNFSWAMDLDPKGAN 772 A+ ++ A+ L P + Sbjct: 125 IPEAIQSYRTALKLKPDFPD 144 Score = 74.8 bits (182), Expect = 2e-13, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 36/88 (40%), Gaps = 6/88 (6%) Query: 699 DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALM 758 + + A++ + A + + ++ P + + + V ++ G+ ALM Sbjct: 3 CSNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALM 62 Query: 759 NFSWAMDLDPKGAN------NQIKEAID 780 ++ A+ + P A+ N +KE D Sbjct: 63 HYKEAIRIQPTFADAYSNMGNTLKELQD 90 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 58/146 (39%) Query: 502 LCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTD 561 L + E +A R++ + + ++ L K + K+ Sbjct: 10 LNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMHYKEAIR 69 Query: 562 MDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621 + +A+ GN ++ A++ + RAIQ++P +A A++ L + + +A+ Sbjct: 70 IQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSGNIPEAI 129 Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYK 647 +R A+++ P +A+ L Sbjct: 130 QSYRTALKLKPDFPDAYCNLAHCLQI 155 Score = 74.1 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 51/126 (40%) Query: 666 PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQE 725 + L ++ ++ E+A KA+ + P + ASVL K K AL Sbjct: 4 SNHADSLNNLANIKREQGYIEEATRLYLKALEVFPDFAAAHSNLASVLQQQGKLKEALMH 63 Query: 726 LEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLP 785 +E +I P + Y +G K+L AL ++ A+ ++P A+ A + Sbjct: 64 YKEAIRIQPTFADAYSNMGNTLKELQDVSGALQCYTRAIQINPAFADAHSNLASIHKDSG 123 Query: 786 DDEEPI 791 + E I Sbjct: 124 NIPEAI 129 >6B85-J nrPDB Length = 223 Score = 146 bits (367), Expect = 6e-35, Method: Composition-based stats. Identities = 46/203 (22%), Positives = 92/203 (45%), Gaps = 7/203 (3%) Query: 506 GRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKN 565 +++++ +I + + + M + L Q + + +D+ Sbjct: 27 AIIWYQITTNPDTSQIATLLSMQ-LLLIALMLVVIALLLSRQTEQVAESIRRDV------ 79 Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625 S A+ G SL +A + +++AI++DPN A A+ LLG + LD+A ++ Sbjct: 80 SALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYK 139 Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685 AI + P +AW LG + K + A ++KA++++P+ + +G V L + Sbjct: 140 KAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRL 199 Query: 686 EKALDTLNKAIVIDPKNPLCKFH 708 ++A + KAI +DP + H Sbjct: 200 DEAAEAYKKAIELDPNDLEHHHH 222 Score = 116 bits (291), Expect = 3e-26, Method: Composition-based stats. Identities = 36/162 (22%), Positives = 71/162 (43%), Gaps = 5/162 (3%) Query: 579 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAW 638 L R+ + + +R + A AY +LG L L A ++ AI ++P AW Sbjct: 64 LSRQTEQVAESIRRDV-----SALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAW 118 Query: 639 YGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698 LG + K ++ A ++KA+++ P + +G V L + ++A + KAI + Sbjct: 119 LLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIEL 178 Query: 699 DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740 DP++ VL + A + ++ ++ P + + Sbjct: 179 DPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLEHH 220 Score = 106 bits (263), Expect = 5e-23, Method: Composition-based stats. Identities = 37/166 (22%), Positives = 79/166 (47%), Gaps = 5/166 (3%) Query: 603 AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKAL 662 A L+ +L+ + ++ R + A+ LG++ + SLA ++KA+ Sbjct: 54 ALMLVVIALLLSRQTEQVAESIRRDVS-----ALAYVMLGLLLSLLNRLSLAAEAYKKAI 108 Query: 663 DINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSA 722 +++P ++ +G V LK+ ++A + KAI + P + VL + A Sbjct: 109 ELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEA 168 Query: 723 LQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP 768 + ++ ++ P+++ + +GKV +KLG+ A + A++LDP Sbjct: 169 AEAYKKAIELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDP 214 Score = 77.5 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 30/134 (22%), Positives = 61/134 (45%) Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELE 727 S++ +G++ L + A + KAI +DP + L SVL ++ A + + Sbjct: 80 SALAYVMLGLLLSLLNRLSLAAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYK 139 Query: 728 ELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDD 787 + ++ P ++ + +GKV +KLG+ A + A++LDP+ A + L Sbjct: 140 KAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKAIELDPEDAEAWKELGKVLEKLGRL 199 Query: 788 EEPITQEEQIMGTD 801 +E ++ + D Sbjct: 200 DEAAEAYKKAIELD 213 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 39/103 (37%), Gaps = 2/103 (1%) Query: 500 WVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDL 559 W+L +G +L +A + + ++ + L L + + K Sbjct: 118 WLL--LGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVLEKLGRLDEAAEAYKKA 175 Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAY 602 ++D EAW G D A + +++AI++DPN Sbjct: 176 IELDPEDAEAWKELGKVLEKLGRLDEAAEAYKKAIELDPNDLE 218 Score = 45.6 bits (106), Expect = 1e-04, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 37/86 (43%) Query: 722 ALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDK 781 A + ++ ++ P ++L + L+G V +KL + A + A++L P A+ + Sbjct: 100 AAEAYKKAIELDPNDALAWLLLGSVLEKLKRLDEAAEAYKKAIELKPNDASAWKELGKVL 159 Query: 782 RYLPDDEEPITQEEQIMGTDESQESS 807 L +E ++ + D + Sbjct: 160 EKLGRLDEAAEAYKKAIELDPEDAEA 185 >5JJT-A nrPDB Length = 479 Score = 126 bits (316), Expect = 5e-29, Method: Composition-based stats. Identities = 35/178 (19%), Positives = 70/178 (39%), Gaps = 15/178 (8%) Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 + +K K+S A + KA+++N ++V + L++ A+ + Sbjct: 8 RAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSAIQDAS 67 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQT 753 KAI +D + + R + A K+K AL++ +++K++ P + +KL + Sbjct: 68 KAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDP-------DATRKLKEC 120 Query: 754 HLALMNFSWAMDLD-PKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTD 810 A+M + + P + E+ID + E Q G E D Sbjct: 121 EKAVMKLKFEEAISVPVSERRSVAESIDFHTIE-------VEPQYSGARIEGEEVTLD 171 Score = 62.1 bits (149), Expect = 1e-09, Method: Composition-based stats. Identities = 31/133 (23%), Positives = 52/133 (39%), Gaps = 7/133 (5%) Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 + D + E + + N ++ AI + +AI+++ N A + EE A Sbjct: 3 NSDVSRAEEFKSQANEAFKGHKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEEYGSA 62 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQH 680 + AI V+ R+ +Y G Y KF A FQ+ ++P Sbjct: 63 IQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDA-------TR 115 Query: 681 ALKKSEKALDTLN 693 LK+ EKA+ L Sbjct: 116 KLKECEKAVMKLK 128 Score = 55.6 bits (132), Expect = 9e-08, Method: Composition-based stats. Identities = 27/130 (20%), Positives = 50/130 (38%), Gaps = 5/130 (3%) Query: 523 SEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQRE 582 S+V R E ++ + E + K + L +++ N+ W + E Sbjct: 4 SDVSRAEEFKSQANEAFKG-----HKYSSAIDLYTKAIELNSNNAVYWANRAFAHTKLEE 58 Query: 583 HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLG 642 + AI+ +AI+VD Y+ Y G ++ + AL F+ R++P +A L Sbjct: 59 YGSAIQDASKAIEVDSRYSKGYYRRGAAYLAMGKFKDALKDFQQVKRLSPNDPDATRKLK 118 Query: 643 MIYYKQEKFS 652 K Sbjct: 119 ECEKAVMKLK 128 >5NNP-A nrPDB Length = 745 Score = 83.7 bits (205), Expect = 3e-16, Method: Composition-based stats. Identities = 42/256 (16%), Positives = 84/256 (32%), Gaps = 8/256 (3%) Query: 509 YFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPE 568 ++E +Y + + ++ + + M + + L K L+K+ +D S Sbjct: 20 HYEDKQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSYI 79 Query: 569 AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAI 628 W G + + D AIK ++ A++++P L + + + N + Sbjct: 80 CWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRDYAGYVQSRLNML 139 Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEM---HFQKALDINPQSSVLLCHIGVVQH----- 680 + P+ W L + Y+ + AE ++K+L P + L ++ Sbjct: 140 KARPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSEALLYKNTIIA 199 Query: 681 ALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740 E+AL L RAS L + A + L P+ Y Sbjct: 200 ERGDIERALQHLETDCKHCLDRLAVMELRASYLSKLARKDEAAKAYRALLDRNPEHMDYY 259 Query: 741 FLIGKVYKKLGQTHLA 756 + A Sbjct: 260 KGLISALDISADDEEA 275 Score = 67.5 bits (163), Expect = 2e-11, Method: Composition-based stats. Identities = 39/256 (15%), Positives = 87/256 (33%), Gaps = 42/256 (16%) Query: 577 FSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYN 636 +++ +K ++ ++ +P + ++ + ++A A + A+ ++ + Y Sbjct: 20 HYEDKQYKRGLKAAEQILKKNPKHGDTMSMKALILNAQGKTEEAFALAKEALTIDMKSYI 79 Query: 637 AWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL------------------------- 671 W+ G++Y + F A ++ AL + P+S + Sbjct: 80 CWHVYGILYRTNKNFDEAIKAYKFALKLEPESHQIQRDLAVLQIQMRDYAGYVQSRLNML 139 Query: 672 ---------LCHIGVVQHALKKSEKA---LDTLNKAIVIDP-----KNPLCKFHRASVLF 714 + + H EKA L T K++ P ++ ++ +++ Sbjct: 140 KARPQIRQNWTALAIAYHLEGNLEKAEHILTTYEKSLTTPPPKTDLEHSEALLYKNTIIA 199 Query: 715 ANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ 774 + ALQ LE + V L KL + A + +D +P+ + Sbjct: 200 ERGDIERALQHLETDCKHCLDRLAVMELRASYLSKLARKDEAAKAYRALLDRNPEHMDYY 259 Query: 775 IKEAIDKRYLPDDEEP 790 DDEE Sbjct: 260 KGLISALDISADDEEA 275 Score = 48.6 bits (114), Expect = 1e-05, Method: Composition-based stats. Identities = 27/149 (18%), Positives = 54/149 (36%), Gaps = 13/149 (8%) Query: 631 NPRHYNAWYGLGM--IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 + A Y L YY + A + +KA++++P++ + KA Sbjct: 368 SKGKGAALYYLAQHYNYYMSRDLTRALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKA 427 Query: 689 LDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLI----- 743 +T++ A +DPK+ A N + + AL + + + L Sbjct: 428 AETMDYARSLDPKDRYINSKAAKYQLRNNENEKALATMGLFTRAETAGGPLADLTDMQCI 487 Query: 744 ------GKVYKKLGQTHLALMNFSWAMDL 766 G+ +++ G T LAL + + Sbjct: 488 WFLTEDGEAWQRRGNTALALKRYHTVFSI 516 Score = 43.6 bits (101), Expect = 4e-04, Method: Composition-based stats. Identities = 21/170 (12%), Positives = 49/170 (28%), Gaps = 20/170 (11%) Query: 577 FSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYN 636 + + R+ A+++ ++AI++DP + F +L KA A ++P+ Sbjct: 384 YYMSRDLTRALEYVEKAIELDPKNVDFHMTKARIFKHQGDLAKAAETMDYARSLDPKDRY 443 Query: 637 AWYGLGMIYYKQEKFSLAEMH---FQKA---------------LDINPQSSVLLCHIGVV 678 + + A F +A + + G Sbjct: 444 INSKAAKYQLRNNENEKALATMGLFTRAETAGGPLADLTDMQCIWFLTEDGEAWQRRGNT 503 Query: 679 QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASV--LFANEKYKSALQEL 726 ALK+ + + + +++ L+E Sbjct: 504 ALALKRYHTVFSIFDTWQEDQFDFHSFSLRKGQIRAYVDMVRWEDRLREH 553 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 46/328 (14%), Positives = 96/328 (29%), Gaps = 32/328 (9%) Query: 468 EMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRR 527 E+ YL+ + + A + L + + + I + + ++ E Sbjct: 226 ELRASYLSKLARKDEAAKAYRALLDRNPEHMDYYKGLISALDISADDEEAQKAVYDEYAA 285 Query: 528 IENYRVEGMEIYSTTLW-HLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFS--LQRE-- 582 + L + A + L+ DK P + + +S ++E Sbjct: 286 KYPRSDAAKRLPLNFLSGERFRTTAKAYLTLMF---DKGVPSTFANLKHLYSDSFKKETL 342 Query: 583 HDIAIKFFQRAIQVDPNYAYA-------------YTLLGHEFVLTEELDKALACFRNAIR 629 +A ++ + P+ A Y + + ++ +L +AL AI Sbjct: 343 ASLAEEYLNEYVNARPSDNQADGDGSKGKGAALYYLAQHYNYYMSRDLTRALEYVEKAIE 402 Query: 630 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKAL 689 ++P++ + I+ Q + A A ++P+ + Q ++EKAL Sbjct: 403 LDPKNVDFHMTKARIFKHQGDLAKAAETMDYARSLDPKDRYINSKAAKYQLRNNENEKAL 462 Query: 690 DTL----NKAIVIDPKNPLCKFHR-------ASVLFANEKYKSALQELEELKQIVPKESL 738 T+ P L AL+ + I Sbjct: 463 ATMGLFTRAETAGGPLADLTDMQCIWFLTEDGEAWQRRGNTALALKRYHTVFSIFDTWQE 522 Query: 739 VYFLIGKVYKKLGQTHLALMNFSWAMDL 766 F + GQ + W L Sbjct: 523 DQFDFHSFSLRKGQIRAYVDMVRWEDRL 550 >2GW1-A nrPDB Length = 514 Score = 82.5 bits (202), Expect = 7e-16, Method: Composition-based stats. Identities = 58/287 (20%), Positives = 104/287 (36%), Gaps = 27/287 (9%) Query: 555 LSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL--LGHEFV 612 L L+++ K SPE++ A F+ A + F+ Q+D N L Sbjct: 190 LMNGLSNLYKRSPESYDKADESFT------KAARLFEE--QLDKNNEDEKLKEKLAISLE 241 Query: 613 LTEELD-------KALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN 665 T A + AI + PR N++ + +I + + +F KAL ++ Sbjct: 242 HTGIFKFLKNDPLGAHEDIKKAIELFPR-VNSYIYMALIMADRNDSTEYYNYFDKALKLD 300 Query: 666 PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQE 725 +S + H G + L+ ++A +KA +DP+N A + + K+ Sbjct: 301 SNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENIFPYIQLACLAYRENKFDDCETL 360 Query: 726 LEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK--GANNQIKEAIDKRY 783 E K+ P+ V ++ AL + A++L+ K G I + K Sbjct: 361 FSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELENKLDGIYVGIAPLVGKAT 420 Query: 784 L-------PDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDE 823 L + E E+ D E + +L + DE Sbjct: 421 LLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQEDIDE 467 Score = 61.4 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 23/153 (15%), Positives = 59/153 (38%), Gaps = 4/153 (2%) Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 + A G +++ +K+ A ++ AL++ + V ++ ++ +K ++ Sbjct: 5 YALALKDKGNQFFRNKKYDDAIKYYNWALELK-EDPVFYSNLSACYVSVGDLKKVVEMST 63 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL-KQIVPKESLVYFLIGKVY--KKL 750 KA+ + P RAS K+ A+ +L L ++ + ++ + + + Sbjct: 64 KALELKPDYSKVLLRRASANEGLGKFADAMFDLSVLSLNGDFNDASIEPMLERNLNKQAM 123 Query: 751 GQTHLALMNFSWAMDLDPKGANNQIKEAIDKRY 783 + + A + + KE DK+ Sbjct: 124 SKLKEKFGDIDTATATPTELSTQPAKERKDKQE 156 Score = 59.8 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 34/200 (17%), Positives = 64/200 (32%), Gaps = 9/200 (4%) Query: 542 TLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYA 601 + +D N+ + G + + +D A K F +A ++DP Sbjct: 279 IMADRNDSTEYYNYFDKALKLDSNNSSVYYHRGQMNFILQNYDQAGKDFDKAKELDPENI 338 Query: 602 YAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 661 + Y L + D F A R P I + F A + A Sbjct: 339 FPYIQLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLA 398 Query: 662 LDINPQSSVLLCHIGVV---------QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASV 712 +++ + + I + ++ +A + L KA +DP++ K A + Sbjct: 399 IELENKLDGIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQM 458 Query: 713 LFANEKYKSALQELEELKQI 732 E A+ EE + Sbjct: 459 KLQQEDIDEAITLFEESADL 478 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 25/137 (18%), Positives = 50/137 (36%), Gaps = 9/137 (6%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQ---KDVALSVLSKDLT 560 Q+ + +++ E +FSE +R E ++ L K + L+ +L Sbjct: 343 QLACLAYRENKFDDCETLFSEAKRKFPEAPEVPNFFAEILTDKNDFDKALKQYDLAIELE 402 Query: 561 D-MDKNSPEAWCAAGNCFSLQRE-----HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLT 614 + +D G L R A ++A ++DP A L + Sbjct: 403 NKLDGIYVGIAPLVGKATLLTRNPTVENFIEATNLLEKASKLDPRSEQAKIGLAQMKLQQ 462 Query: 615 EELDKALACFRNAIRVN 631 E++D+A+ F + + Sbjct: 463 EDIDEAITLFEESADLA 479 Score = 30.9 bits (68), Expect = 2.5, Method: Composition-based stats. Identities = 29/238 (12%), Positives = 77/238 (32%), Gaps = 29/238 (12%) Query: 564 KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC 623 K P + C+ + ++ +A+++ P+Y+ + A+ Sbjct: 36 KEDPVFYSNLSACYVSVGDLKKVVEMSTKALELKPDYSKVLLRRASANEGLGKFADAMFD 95 Query: 624 FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 + + +N +A ++ A ++ + ++ Q A + Sbjct: 96 -LSVLSLNGDFNDAS---IEPMLERNLNKQAMSKLKEKFG-DIDTATATPTELSTQPAKE 150 Query: 684 KSEKALDT---------------------LNKAIVIDPKNPLCKFHRASVLFANEKYKSA 722 + +K + +++ D + + + E Y A Sbjct: 151 RKDKQENLPSVTSMASFFGIFKPELTFANYDESNEADKELMNGLSNL--YKRSPESYDKA 208 Query: 723 LQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 + + ++ ++ K+ +KL + F + + DP GA+ IK+AI+ Sbjct: 209 DESFTKAARLFEEQLDKNNEDEKLKEKLAISLEHTGIFKF-LKNDPLGAHEDIKKAIE 265 >6FO1-G nrPDB Length = 665 Score = 81.0 bits (198), Expect = 2e-15, Method: Composition-based stats. Identities = 46/277 (16%), Positives = 95/277 (34%), Gaps = 19/277 (6%) Query: 540 STTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPN 599 + K D D +P + + ++ +A A+ ++ + Sbjct: 140 GNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAVAESDCNLAVALNRS 199 Query: 600 YAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYY----KQEKFSLAE 655 Y AY+ G ++L++A + + + P ++ A L I K+ + Sbjct: 200 YTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKENSYPKEA 259 Query: 656 MHF-------QKALDINPQSSVLLCH--IGVVQHALKKSEKALDTLNKAIVIDPKNPLCK 706 +K ++ + G K E+A++ + I D N L Sbjct: 260 DIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADGANALLP 319 Query: 707 FHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 +RA +KY+ A ++ + + S + G LG+ + A +F + L Sbjct: 320 ANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDFETVLLL 379 Query: 767 DP------KGANNQIKEAIDKRYLPDDEEPITQEEQI 797 +P + KE I+K + D TQ + + Sbjct: 380 EPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNV 416 Score = 79.8 bits (195), Expect = 4e-15, Method: Composition-based stats. Identities = 36/176 (20%), Positives = 70/176 (39%), Gaps = 14/176 (7%) Query: 628 IRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEK 687 I V+ + G Y+KQ K+ A + K +D +P + VL + LKK Sbjct: 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAV 185 Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747 A N A+ ++ R + FA +K + A ++ E + ++ P + K+ Sbjct: 186 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIS 245 Query: 748 KKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRY----LPDDEEPITQEEQIMG 799 + L + PK A+ IK +R + ++ I+++++ G Sbjct: 246 QALASKENSY----------PKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNG 291 Score = 70.2 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 32/162 (19%), Positives = 62/162 (38%), Gaps = 1/162 (0%) Query: 662 LDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKS 721 + ++ Q +++L G K ++A+D K + DP NP+ +RAS F +K+ Sbjct: 126 IHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKFAV 185 Query: 722 ALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDK 781 A + + + Y G L + A ++ ++L+P + Sbjct: 186 AESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKIS 245 Query: 782 RYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHA-AESD 822 + L E +E I+ E +A + A +E D Sbjct: 246 QALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKD 287 Score = 69.4 bits (168), Expect = 6e-12, Method: Composition-based stats. Identities = 44/302 (14%), Positives = 102/302 (33%), Gaps = 53/302 (17%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDL- 559 VL + G YF+ +Y +A +++ + Y + + + K A++ +L Sbjct: 135 VLKEKGNKYFKQGKYDEAIDCYTKGMDADPYN-PVLPTNRASAYFRLKKFAVAESDCNLA 193 Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLL------------ 607 ++++ +A+ G ++ + A K ++R ++++PN A L Sbjct: 194 VALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRKISQALASKEN 253 Query: 608 -----------------------------------GHEFVLTEELDKALACFRNAIRVNP 632 G+ F + ++A+ C+ I + Sbjct: 254 SYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIECYTRGIAADG 313 Query: 633 RHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTL 692 + M Y K +K+ AE +A+ ++ S G + L K +A Sbjct: 314 ANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFLGKLNEAKQDF 373 Query: 693 NKAIVIDPKNPLCKFHRASVLFAN---EKYKSA-LQELEELKQIVPKESLVYFLIGKVYK 748 ++++P N + + + L + + P ++ + K K Sbjct: 374 ETVLLLEPGNKQAVTELSKIKKELIEKGHWDDVFLDSTQRQNVVKPIDNPPHPGSTKPLK 433 Query: 749 KL 750 K+ Sbjct: 434 KV 435 Score = 67.1 bits (162), Expect = 3e-11, Method: Composition-based stats. Identities = 42/268 (15%), Positives = 96/268 (35%), Gaps = 13/268 (4%) Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 D +D GN + Q ++D AI + + + DP T + ++ Sbjct: 124 DGIHVDSQKALVLKEKGNKYFKQGKYDEAIDCYTKGMDADPYNPVLPTNRASAYFRLKKF 183 Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 A + A+ +N + A+ G + +K A+ +++ L++ P + + Sbjct: 184 AVAESDCNLAVALNRSYTKAYSRRGAARFALQKLEEAKKDYERVLELEPNNFEATNELRK 243 Query: 678 VQHALKKSE-----------KALDTLNKAIV--IDPKNPLCKFHRASVLFANEKYKSALQ 724 + AL E K+ + K I + + + + R + F KY+ A++ Sbjct: 244 ISQALASKENSYPKEADIVIKSTEGERKQIEAQQNKQQAISEKDRGNGFFKEGKYERAIE 303 Query: 725 ELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYL 784 +L+ Y K+ + A + + A+ LD + + + +L Sbjct: 304 CYTRGIAADGANALLPANRAMAYLKIQKYEEAEKDCTQAILLDGSYSKAFARRGTARTFL 363 Query: 785 PDDEEPITQEEQIMGTDESQESSMTDAD 812 E E ++ + + ++T+ Sbjct: 364 GKLNEAKQDFETVLLLEPGNKQAVTELS 391 >4JA9-A nrPDB Length = 488 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 62/145 (42%), Gaps = 7/145 (4%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 Y+K + + A + +A+++NP +++ + + + AL +AI +D K Sbjct: 27 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 86 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764 + RA+ A K+++AL++ E + ++ P + K + + ++ Sbjct: 87 GYYRRAASNMALGKFRAALRDYETVVKVKPNDK-------DAKMKYQECSKIVKQKAFER 139 Query: 765 DLDPKGANNQIKEAIDKRYLPDDEE 789 + + +++D + ++E Sbjct: 140 AIAGDEHRRSVVDSLDIESMTIEDE 164 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 48/124 (38%), Gaps = 4/124 (3%) Query: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668 +++ ++ + A+ + AI +NP + + + Y + E + A +A++++ + Sbjct: 25 NDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKY 84 Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPK--NPLCKFHRASVLFANEKYKSAL--Q 724 AL K AL + + P + K+ S + + ++ A+ Sbjct: 85 IKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDAKMKYQECSKIVKQKAFERAIAGD 144 Query: 725 ELEE 728 E Sbjct: 145 EHRR 148 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 22/111 (19%), Positives = 45/111 (40%) Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 + E N + ++++ AIKF+ +AI+++P+ A Y ++ TE A Sbjct: 11 EGTLKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYA 70 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671 L AI ++ ++ +Y KF A ++ + + P Sbjct: 71 LGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPNDKDA 121 Score = 37.9 bits (86), Expect = 0.021, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 42/133 (31%), Gaps = 36/133 (27%) Query: 506 GRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKN 565 YF+ +Y A + +S+ + S +++ + Sbjct: 24 ANDYFKAKDYENAIKFYSQAIELNP---------SNAIYYGNR----------------- 57 Query: 566 SPEAWCAAGNCFSLQRE-HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 + L+ E + A+ RAI++D Y Y + + AL + Sbjct: 58 ---------SLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDY 108 Query: 625 RNAIRVNPRHYNA 637 ++V P +A Sbjct: 109 ETVVKVKPNDKDA 121 >1A17-A nrPDB Length = 166 Score = 74.1 bits (180), Expect = 3e-13, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 63/145 (43%), Gaps = 7/145 (4%) Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPL 704 Y+K + + A + +A+++NP +++ + + + AL +AI +D K Sbjct: 23 YFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKYIK 82 Query: 705 CKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAM 764 + RA+ A K+++AL++ E + ++ P + K + + + ++ Sbjct: 83 GYYRRAASNMALGKFRAALRDYETVVKVKPHDK-------DAKMKYQECNKIVKQKAFER 135 Query: 765 DLDPKGANNQIKEAIDKRYLPDDEE 789 + + +++D + ++E Sbjct: 136 AIAGDEHKRSVVDSLDIESMTIEDE 160 Score = 54.8 bits (130), Expect = 1e-07, Method: Composition-based stats. Identities = 18/117 (15%), Positives = 48/117 (41%), Gaps = 2/117 (1%) Query: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQS 668 +++ ++ + A+ + AI +NP + + + Y + E + A +A++++ + Sbjct: 21 NDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYALGDATRAIELDKKY 80 Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDP--KNPLCKFHRASVLFANEKYKSAL 723 AL K AL + + P K+ K+ + + + ++ A+ Sbjct: 81 IKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDAKMKYQECNKIVKQKAFERAI 137 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 45/111 (40%) Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 D E N + ++++ AIKF+ +AI+++P+ A Y ++ TE A Sbjct: 7 DGALKRAEELKTQANDYFKAKDYENAIKFYSQAIELNPSNAIYYGNRSLAYLRTECYGYA 66 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL 671 L AI ++ ++ +Y KF A ++ + + P Sbjct: 67 LGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDYETVVKVKPHDKDA 117 Score = 36.3 bits (82), Expect = 0.060, Method: Composition-based stats. Identities = 20/133 (15%), Positives = 42/133 (31%), Gaps = 36/133 (27%) Query: 506 GRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKN 565 YF+ +Y A + +S+ + S +++ + Sbjct: 20 ANDYFKAKDYENAIKFYSQAIELNP---------SNAIYYGNR----------------- 53 Query: 566 SPEAWCAAGNCFSLQRE-HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 + L+ E + A+ RAI++D Y Y + + AL + Sbjct: 54 ---------SLAYLRTECYGYALGDATRAIELDKKYIKGYYRRAASNMALGKFRAALRDY 104 Query: 625 RNAIRVNPRHYNA 637 ++V P +A Sbjct: 105 ETVVKVKPHDKDA 117 >2Y4T-A nrPDB Length = 450 Score = 71.4 bits (173), Expect = 2e-12, Method: Composition-based stats. Identities = 52/285 (18%), Positives = 92/285 (32%), Gaps = 27/285 (9%) Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625 E G + A+ F A+ DP+ AY F+ + AL Sbjct: 25 DVEKHLELGKKLLAAGQLADALSQFHAAVDGDPDNYIAYYRRATVFLAMGKSKAALPDLT 84 Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP---------------QSSV 670 I++ A G + KQ K AE F+K L NP Sbjct: 85 KVIQLKMDFTAARLQRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQ 144 Query: 671 LLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELK 730 L + A+ L+K + + + + RA + + A+ +L+ Sbjct: 145 RLRSQALNAFGSGDYTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAAS 204 Query: 731 QIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDP------------KGANNQIKEA 778 ++ + ++ I +Y +LG L+L + LD K N I+ A Sbjct: 205 KLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESA 264 Query: 779 IDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDE 823 + + ++ E +M T+ S + + H DE Sbjct: 265 EELIRDGRYTDATSKYESVMKTEPSIAEYTVRSKERICHCFSKDE 309 Score = 52.1 bits (123), Expect = 1e-06, Method: Composition-based stats. Identities = 40/290 (13%), Positives = 92/290 (31%), Gaps = 32/290 (11%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTL----WHLQKDVALSVLSK-- 557 Q G + + +AE F +V + E E S + + AL+ Sbjct: 99 QRGHLLLKQGKLDEAEDDFKKVLKSNPSENEEKEAQSQLIKSDEMQRLRSQALNAFGSGD 158 Query: 558 ---------DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG 608 + ++ E CF + E AI + A ++ + A+ + Sbjct: 159 YTAAIAFLDKILEVCVWDAELRELRAECFIKEGEPRKAISDLKAASKLKNDNTEAFYKIS 218 Query: 609 HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH----------- 657 + + + +L+ R ++++ H + + + AE Sbjct: 219 TLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYKQVKKLNKLIESAEELIRDGRYTDATS 278 Query: 658 -FQKALDINPQSSVLLCH----IGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASV 712 ++ + P + I +K +A+ ++ + ++P N RA Sbjct: 279 KYESVMKTEPSIAEYTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEA 338 Query: 713 LFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSW 762 E Y A+Q+ E ++ + + + K + L Q+ + Sbjct: 339 YLIEEMYDEAIQDYETAQEHNENDQQIREGLEKAQRLLKQSQKR-DYYKI 387 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 38/260 (14%), Positives = 83/260 (31%), Gaps = 44/260 (16%) Query: 482 KEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYST 541 ++AI+ L + +I Y++L ++ + E +++ Y Sbjct: 194 RKAISDLKAASKLKNDNTEAFYKISTLYYQLGDHELSLSEVRECLKLDQDHKRCFAHYK- 252 Query: 542 TLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYA 601 ++K L +++L + A ++ ++ +P+ A Sbjct: 253 ---QVKKLNKLIESAEELIR------------------DGRYTDATSKYESVMKTEPSIA 291 Query: 602 YAYTLLG-----HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656 YT+ H F E+ +A+ +++ P + NA Y +E + A Sbjct: 292 E-YTVRSKERICHCFSKDEKPVEAIRVCSEVLQMEPDNVNALKDRAEAYLIEEMYDEAIQ 350 Query: 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716 ++ A + N Q + EKA L ++ D + V Sbjct: 351 DYETAQEHNEND----------QQIREGLEKAQRLLKQSQKRD------YYKILGVKRNA 394 Query: 717 EKYKSALQELEELKQIVPKE 736 +K + + Q P Sbjct: 395 KKQEIIKAYRKLALQWHPDN 414 >5FZQ-A nrPDB Length = 131 Score = 69.8 bits (169), Expect = 4e-12, Method: Composition-based stats. Identities = 20/99 (20%), Positives = 48/99 (48%) Query: 639 YGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698 L + ++ K A + +KA+ ++P + L ++ + K+E+A+ + KA+ + Sbjct: 9 SNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRKAVSL 68 Query: 699 DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 DP N + A +L K + A++ + + ++ K + Sbjct: 69 DPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAA 107 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 23/129 (17%), Positives = 56/129 (43%), Gaps = 1/129 (0%) Query: 599 NYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHF 658 N + L + + ++A+ R A+ ++P + L + ++ K A + Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 659 QKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI-DPKNPLCKFHRASVLFANE 717 +KA+ ++P + L ++ V+ K+E+A+ + KA+ + D H+ + Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAAKGSTLHKNAAARRKS 122 Query: 718 KYKSALQEL 726 + +Q+L Sbjct: 123 RLMRKVQKL 131 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 45/108 (41%) Query: 667 QSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQEL 726 S L ++ + K+E+A+ + KA+ +DP N + A++L K + A++ + Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 727 EELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQ 774 + + P + + + G+ A+ A+ L K A Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSLIDKAAKGS 110 Score = 64.4 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 20/100 (20%), Positives = 48/100 (48%) Query: 565 NSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACF 624 NS + N + + + + AIK+ ++A+ +DPN + L + + ++A+ Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 R A+ ++P + L ++ ++ K A + +KA+ + Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 59.0 bits (141), Expect = 8e-09, Method: Composition-based stats. Identities = 16/98 (16%), Positives = 40/98 (40%) Query: 533 VEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQR 592 ++ + + L K + +D N+ + N + + + + AIK+ ++ Sbjct: 5 IKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYMRK 64 Query: 593 AIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV 630 A+ +DPN + L + ++A+ R A+ + Sbjct: 65 AVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 32/91 (35%) Query: 701 KNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNF 760 + + A++L K + A++ + + + P + + + G+ A+ Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 761 SWAMDLDPKGANNQIKEAIDKRYLPDDEEPI 791 A+ LDP A+ EE I Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAI 93 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 11/100 (11%), Positives = 37/100 (37%) Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLS 556 N+ L + + + +A + + ++ ++ + + L K Sbjct: 3 NSIKTLSNLANLLAQEGKAEEAIKYMRKAVSLDPNNIKTLSNLANLLAQEGKAEEAIKYM 62 Query: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV 596 + +D N+ + + + + + AIK+ ++A+ + Sbjct: 63 RKAVSLDPNNIKTLSNLAVLLAQEGKAEEAIKYMRKAVSL 102 >1QZ2-A nrPDB Length = 336 Score = 66.0 bits (159), Expect = 7e-11, Method: Composition-based stats. Identities = 54/327 (16%), Positives = 115/327 (35%), Gaps = 44/327 (13%) Query: 497 NTGWVLCQIGRAYFELSEYMQAERIFS--EVRRIE-NY----RVEGMEIYSTTLWHLQKD 549 N G ++ Y++ + Q E F E ++ Y ++ ME ++ +L+ Sbjct: 42 NEGAIVEVALEGYYKDKLFDQRELRFEIGEGENLDLPYGLERAIQRMEKGEHSIVYLKPS 101 Query: 550 VALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDI--AIKFFQRAIQVDPNYAYAYTLL 607 A + K+ + N+ + F +E + + +++ V Sbjct: 102 YAFGSVGKEKFQIPPNAELKYELHLKSFEKAKESWEMNSEEKLEQSTIVKER-------- 153 Query: 608 GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 G + + +AL ++ + W + Y A+ +AL + Sbjct: 154 GTVYFKEGKYKQALLQYKKIVS--------W----LEYESSFSNEEAQKA--QALRLASH 199 Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELE 727 ++ +CH+ L+ A+++ NKA+ +D N F R A ++ A + + Sbjct: 200 LNLAMCHL-----KLQAFSAAIESCNKALELDSNNEKGLFRRGEAHLAVNDFELARADFQ 254 Query: 728 ELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDD 787 ++ Q+ P + +++ + LA +A +E K Sbjct: 255 KVLQLYPNNKAAKTQLAVCQQRI-RRQLAREKKLYA----NMFERLAEEENKAKAEASSG 309 Query: 788 EEPI---TQEEQIMGTDESQESSMTDA 811 + P +EEQ T SQ T+A Sbjct: 310 DHPTDTEMKEEQKSNTAGSQSQVETEA 336 >5AEM-A nrPDB Length = 447 Score = 63.3 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 35/233 (15%), Positives = 74/233 (31%), Gaps = 25/233 (10%) Query: 566 SPEAWCAAGNCFSLQREHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC 623 PE +D+ A + F I+ D AY LG + L L+ Sbjct: 6 DPEVAQLLSQANEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNS 65 Query: 624 FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 + A +N + W + ++ + A F + + +NP + ++ Sbjct: 66 WFLAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTG 125 Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLI 743 + +ALD + + +P + A + ++ + +++ ++ + Sbjct: 126 QLARALDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIELYMKVFNANVERREA---- 181 Query: 744 GKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQ 796 L AL E D D++EP+ Q+E Sbjct: 182 -----ILAALENALD----------SSDEESAAEGED----ADEKEPLEQDED 215 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 38/245 (15%), Positives = 79/245 (32%), Gaps = 10/245 (4%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 +L Q A+ ++ AER+F+EV + + E + Sbjct: 12 LLSQANEAFVR-NDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLNDCCNSWFLAA 70 Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 ++ + E W + AI F R I ++P + + T +L +A Sbjct: 71 HLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSMLYKKTGQLARA 130 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVL-LCHIGVVQ 679 L F+ NP N L ++Y ++ + + K + N + L + Sbjct: 131 LDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIELYMKVFNANVERREAILAALENAL 190 Query: 680 --HALKKSEKALDTLNKA-IVIDPK---NPLCKFHRASVLFANEKYKSALQELEELKQIV 733 + + + D K + D P + + + + L L ++ Sbjct: 191 DSSDEESAAEGEDADEKEPLEQDEDRQMFPDINWKKIDAKYKCIPFD--WSSLNILAELF 248 Query: 734 PKESL 738 K ++ Sbjct: 249 LKLAV 253 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 26/170 (15%), Positives = 65/170 (38%), Gaps = 1/170 (0%) Query: 525 VRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHD 584 ++ V + + + L ++ D + A+ G+ + LQ + Sbjct: 2 AMVLDP-EVAQLLSQANEAFVRNDLQVAERLFNEVIKKDARNFAAYETLGDIYQLQGRLN 60 Query: 585 IAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMI 644 + A ++ + + ++ + + +A+ CF I +NP + + Y M+ Sbjct: 61 DCCNSWFLAAHLNASDWEFWKIVAILSADLDHVRQAIYCFSRVISLNPMEWESIYRRSML 120 Query: 645 YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNK 694 Y K + + A FQ+ NP + +L + ++ + E +++ K Sbjct: 121 YKKTGQLARALDGFQRLYMYNPYDANILRELAILYVDYDRIEDSIELYMK 170 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 12/87 (13%), Positives = 31/87 (35%), Gaps = 1/87 (1%) Query: 635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINP-QSSVLLCHIGVVQHALKKSEKALDTLN 693 + ++ + EK+ A F L + +++ + + ++ E A + Sbjct: 348 ADLYFEAATALTRAEKYKEAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYE 407 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYK 720 AI +P + + A V + + Sbjct: 408 LAIKSEPDDLDIRVSLAEVYYRLNDPE 434 Score = 37.5 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 20/142 (14%), Positives = 46/142 (32%), Gaps = 16/142 (11%) Query: 559 LTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD 618 L ++ ++ C + D+A +F+ A E+ Sbjct: 321 LLRLNTDNLVEALNHFQCLYDETFSDVADLYFEAAT---------------ALTRAEKYK 365 Query: 619 KALACFRNAIRVNP-RHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 +A+ F + + R + + L Y + E + A+ ++ A+ P + + Sbjct: 366 EAIDFFTPLLSLEEWRTTDVFKPLARCYKEIESYETAKEFYELAIKSEPDDLDIRVSLAE 425 Query: 678 VQHALKKSEKALDTLNKAIVID 699 V + L E L + + Sbjct: 426 VYYRLNDPETFKHMLVDVVEMR 447 >4HOQ-A nrPDB Length = 482 Score = 62.9 bits (151), Expect = 5e-10, Method: Composition-based stats. Identities = 50/292 (17%), Positives = 100/292 (34%), Gaps = 36/292 (12%) Query: 488 LSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHL- 546 ++ P + Y ++ ++ + E E I ++ Y + Y+ + Sbjct: 208 VTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQ-PYVLR----YAAKFYRRK 262 Query: 547 QKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTL 606 L K ++ S G C+ Q + ++A P Sbjct: 263 NSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQ------MIQIKKATHNRPKGKD---- 312 Query: 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 + + E + A+ F+ A+ + A+ L +Y + ++S AE F+KAL + Sbjct: 313 ---KLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN 369 Query: 667 QSSVLLCHIG-----VVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKS 721 + I + K A+ +A+ + ++PL K S Sbjct: 370 ITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPL-----------RTKLTS 418 Query: 722 ALQELEELKQIV-PKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGAN 772 AL++L + + +G VYK G+ A + A +DP+ A Sbjct: 419 ALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470 Score = 59.8 bits (143), Expect = 4e-09, Method: Composition-based stats. Identities = 33/229 (14%), Positives = 83/229 (36%), Gaps = 30/229 (13%) Query: 572 AAGNCFSLQREHDIAIKFFQRAIQV---------DPNYAYAYTLLGHEFVLTEELDKALA 622 L+ ++ A++ ++A ++ + + + ++L++A Sbjct: 56 LLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEVRSLVTWGNYAWVYYHMDQLEEA-Q 114 Query: 623 CFRNAI-------------RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSS 669 + I ++ + G ++ + + + A+ F+KAL++ P + Sbjct: 115 KYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGKYYQKAKAAFEKALEVEPDNP 174 Query: 670 VLLCHIGVVQHALKKSEK-------ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSA 722 + + L S++ +L L KA+ ++P N K A L Sbjct: 175 EFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEG 234 Query: 723 LQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGA 771 + +EE+ + + V K Y++ + AL A+++ P + Sbjct: 235 EKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283 Score = 53.3 bits (126), Expect = 5e-07, Method: Composition-based stats. Identities = 34/230 (14%), Positives = 75/230 (32%), Gaps = 35/230 (15%) Query: 568 EAWCAAGNCFSLQREHDIAIKFFQR------AIQVDPNY-----------AYAYTLLGHE 610 W + + + A K+ + + NY +A G + Sbjct: 95 VTWGNYAWVYYHMDQLEEAQKYTGKIGNVCKKLSSPSNYKLECPETDCEKGWALLKFGGK 154 Query: 611 FVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFS-------LAEMHFQKALD 663 + KA A F A+ V P + G + Y+ + + +KA+ Sbjct: 155 Y-----YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVKSFSLGPLRKAVT 209 Query: 664 INPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 723 +NP +S + + + + + + + + P + A + AL Sbjct: 210 LNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKAL 269 Query: 724 QELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANN 773 + L++ ++ P S ++ +G Y+ ++ A PKG + Sbjct: 270 ELLKKALEVTPTSSFLHHQMGLCYRAQ------MIQIKKATHNRPKGKDK 313 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 34/228 (14%), Positives = 79/228 (34%), Gaps = 52/228 (22%) Query: 500 WVLCQIGRAYFELSEYMQAERIFSEVRRIEN------------YRVEGMEIYSTTLWH-L 546 +VL + Y + + +A + + + YR + ++I T Sbjct: 250 YVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMIQIKKATHNRPK 309 Query: 547 QKD---------VALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 KD A+ K + D A+ N ++ ++ A F++A++++ Sbjct: 310 GKDKLKVDELISSAIFHF-KAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368 Query: 598 PNYAYAYTLLGHEFVLTEELDK-----ALACFRNAIRVNPR------------------- 633 + + + +E + A+ + A++V R Sbjct: 369 NITDDHKHQIHYHYGRFQEFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRL 428 Query: 634 HYNAW-----YGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIG 676 +NA LG +Y + + A +++KA I+P+++ L + Sbjct: 429 CHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALC 476 >5DSE-A nrPDB Length = 837 Score = 61.4 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 55/137 (40%) Query: 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626 + W A + + A Q A + P + G L +D+A + Sbjct: 690 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEE 749 Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSE 686 A+ ++P H + L +I ++ ++SLAE + A+ +N + + +G V A Sbjct: 750 ALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDA 809 Query: 687 KALDTLNKAIVIDPKNP 703 A + A+ ++ +P Sbjct: 810 AATECFLTALELEASSP 826 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 28/136 (20%), Positives = 52/136 (38%) Query: 635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNK 694 W +Y K + A Q+A ++ P S +L G + ++A + Sbjct: 690 AQIWLHAAEVYIGIGKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEE 749 Query: 695 AIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 754 A+ I P + A +L +Y A + L + Q+ V+ +G+V + G Sbjct: 750 ALAISPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDA 809 Query: 755 LALMNFSWAMDLDPKG 770 A F A++L+ Sbjct: 810 AATECFLTALELEASS 825 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 26/133 (19%), Positives = 50/133 (37%), Gaps = 4/133 (3%) Query: 537 EIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV 596 E+Y K + +++ ++ S G L+ D A ++++ A+ + Sbjct: 698 EVYIGI----GKPAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAI 753 Query: 597 DPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656 P + + L A R+A++VN + W GLG + Q + A Sbjct: 754 SPTHVKSMQRLALILHQLGRYSLAEKILRDAVQVNSTAHEVWNGLGEVLQAQGNDAAATE 813 Query: 657 HFQKALDINPQSS 669 F AL++ S Sbjct: 814 CFLTALELEASSP 826 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 50/269 (18%), Positives = 95/269 (35%), Gaps = 23/269 (8%) Query: 487 ILSHLPSHHYNTGWVLCQIGRAY----FELSEYMQAERIFSEVRRIENYRVEGMEI---Y 539 +LS +P H + L Y L Q E + + R + E + + Sbjct: 338 VLSRIPEHKSDRLISLQSASVVYDLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQF 397 Query: 540 STTLWHLQKDVALSVLSKDLTDMDKNSP-EAWCAAGNCFSLQREHDIAIKFFQRAIQV-D 597 + +L K + K+ + + AA C + A KF + + V + Sbjct: 398 ALSLMAAGKSARAVKVLKECIRLKPDDATIPLLAAKLCMGSLHWLEEAEKFAKTVVDVGE 457 Query: 598 PNY---AYAYTLLG---------HEFVLTEEL--DKALACFRNAIRVNPRHYNAWYGLGM 643 A Y LG +E+ KAL F+ A ++P + A + L + Sbjct: 458 KTSEFKAKGYLALGLTYSLQATDASLRGMQEVLQRKALLAFQRAHSLSPTDHQAAFYLAL 517 Query: 644 IYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNP 703 + A + ++AL + + L + ++ A K AL+ ++ A+ P+N Sbjct: 518 QLAISRQIPEALGYVRQALQLQGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENF 577 Query: 704 LCKFHRASVLFANEKYKSALQELEELKQI 732 + F + + AL + + QI Sbjct: 578 ILLFSKVKLQSLCRGPDEALLTCKHMLQI 606 Score = 49.4 bits (116), Expect = 7e-06, Method: Composition-based stats. Identities = 37/248 (14%), Positives = 81/248 (32%), Gaps = 20/248 (8%) Query: 537 EIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV 596 ++ + L + LS + W + A+K + I++ Sbjct: 361 DLLTIALGRRGQYEMLSECLERAMKFAFEEFHLWYQFALSLMAAGKSARAVKVLKECIRL 420 Query: 597 DPNYA-----YAYTLLG--HEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 649 P+ A A +G H E+ K + + + + LG+ Y Q Sbjct: 421 KPDDATIPLLAAKLCMGSLHWLEEAEKFAKTVVDVGE--KTSEFKAKGYLALGLTYSLQA 478 Query: 650 -----------KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698 A + FQ+A ++P ++ + ++ +AL + +A+ + Sbjct: 479 TDASLRGMQEVLQRKALLAFQRAHSLSPTDHQAAFYLALQLAISRQIPEALGYVRQALQL 538 Query: 699 DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALM 758 + A +L A + Y AL ++ P+ ++ F K+ AL+ Sbjct: 539 QGDDANSLHLLALLLSAQKHYHDALNIIDMALSEYPENFILLFSKVKLQSLCRGPDEALL 598 Query: 759 NFSWAMDL 766 + + Sbjct: 599 TCKHMLQI 606 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 20/128 (15%), Positives = 42/128 (32%), Gaps = 6/128 (4%) Query: 665 NPQSSVLLCHIGVVQHALKKSEKALDTL-NKAIVIDPKNPLCKF-----HRASVLFANEK 718 +P++ + + + +L + A P +P H A V K Sbjct: 646 DPETGSVHATSVAASRVEQALSEVASSLQSSAPKQGPLHPWMTLAQIWLHAAEVYIGIGK 705 Query: 719 YKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEA 778 A +E + P V ++ G++ + G A + A+ + P + + A Sbjct: 706 PAEATACTQEAANLFPMSHNVLYMRGQIAELRGSMDEARRWYEEALAISPTHVKSMQRLA 765 Query: 779 IDKRYLPD 786 + L Sbjct: 766 LILHQLGR 773 >6C95-A nrPDB Length = 866 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 41/242 (16%), Positives = 84/242 (34%), Gaps = 14/242 (5%) Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625 E G + + + A + +R ++ D + + G ++ D+A+ C+R Sbjct: 45 HGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYR 104 Query: 626 NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKS 685 NA++ + + L ++ + + L + P + H L+ Sbjct: 105 NALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDY 164 Query: 686 EKA---LDTLNKAIVIDPK-----NPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 E A L+ K P ++ VL Y+ AL+ L ++ + + Sbjct: 165 EMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALEHLCTYEKQICDKL 224 Query: 738 LVYFLIGKVYKKLGQTHLALMNFSWAMDLDP------KGANNQIKEAIDKRYLPDDEEPI 791 V G++ +L + A + + +P KG +K A L EE Sbjct: 225 AVEETKGELLLQLCRLEDAADVYRGLQERNPENWAYYKGLEKALKPANMLERLKIYEEAW 284 Query: 792 TQ 793 T+ Sbjct: 285 TK 286 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 32/182 (17%), Positives = 72/182 (39%), Gaps = 11/182 (6%) Query: 590 FQRAIQVDPNYAY---AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYY 646 F + I +P +A + G + ++A R +R + + + W+ G++ Sbjct: 32 FCKQILSNPKFAEHGETLAMKGLTLNCLGKKEEAYELVRRGLRNDLKSHVCWHVYGLLQR 91 Query: 647 KQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCK 706 +K+ A ++ AL + + +L + ++Q ++ E +T + + + P Sbjct: 92 SDKKYDEAIKCYRNALKWDKDNLQILRDLSLLQIQMRDLEGYRETRYQLLQLRPAQRASW 151 Query: 707 FHRASVLFANEKYKSA---LQELEELKQIVP-----KESLVYFLIGKVYKKLGQTHLALM 758 A E Y+ A L+E + +Q P + S + +V ++ G AL Sbjct: 152 IGYAIAYHLLEDYEMAAKILEEFRKTQQTSPDKVDYEYSELLLYQNQVLREAGLYREALE 211 Query: 759 NF 760 + Sbjct: 212 HL 213 Score = 37.5 bits (85), Expect = 0.022, Method: Composition-based stats. Identities = 28/180 (15%), Positives = 66/180 (36%), Gaps = 5/180 (2%) Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV---LLCHIGVVQHALK 683 A+ + P+ + + Y +++ ++ L NP+ + L G+ + L Sbjct: 3 AVSLPPKENALFKRILRCYE-HKQYRNGLKFCKQILS-NPKFAEHGETLAMKGLTLNCLG 60 Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLI 743 K E+A + + + + D K+ +C + +++KY A++ + + + Sbjct: 61 KKEEAYELVRRGLRNDLKSHVCWHVYGLLQRSDKKYDEAIKCYRNALKWDKDNLQILRDL 120 Query: 744 GKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDES 803 + ++ + L P + I AI L D E E+ T ++ Sbjct: 121 SLLQIQMRDLEGYRETRYQLLQLRPAQRASWIGYAIAYHLLEDYEMAAKILEEFRKTQQT 180 Score = 32.8 bits (73), Expect = 0.68, Method: Composition-based stats. Identities = 19/137 (13%), Positives = 38/137 (27%), Gaps = 15/137 (10%) Query: 607 LGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINP 666 L + + AL AI P + IY A +A ++ Sbjct: 380 LAQHYDKIGQPSIALEYINTAIESTPTLIELFLVKAKIYKHAGNIKEAARWMDEAQALDT 439 Query: 667 QSSVLLCHIGVVQHALKKSEKALDTLNK-------AIV-----IDPKNPLCKFHRASVLF 714 + ++A + +K A+ + A Sbjct: 440 ADRFINSKCAKYMLKANLIKEAEEMCSKFTREGTSAVENLNEMQCMWF---QTECAQAYK 496 Query: 715 ANEKYKSALQELEELKQ 731 A K+ AL++ E+++ Sbjct: 497 AMNKFGEALKKCHEIER 513 >6AF0-A nrPDB Length = 939 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 51/260 (19%), Positives = 92/260 (35%), Gaps = 41/260 (15%) Query: 490 HLPSHHYNTGWVLCQIGRAYFELSEYMQAE--RIFSEVRRIENYRVEGMEIYSTTLWHLQ 547 L H + + + AY +L E +++ + +E +Y L + Sbjct: 604 LLSRH---SDYTDARTRLAYIKLRRNPNKEGPDAVAKLYQENPSDLEVRGLYGWFLSKVN 660 Query: 548 ---------KDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQRE---------------- 582 +D L DK+ A GN + Sbjct: 661 SKKRPANIAEDPEQRHYKHTLQSYDKHDRYALVGMGNLHLMAAREMRRETEQDRQKRSAA 720 Query: 583 HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVL-TEELDKALACFRNAIRVNPRHYNAWYGL 641 ++ A++FF +A+Q+DP AYA + V ++ AL F +R + + + + Sbjct: 721 YNRAVEFFDKALQLDPKNAYAAQGIAIALVEDRKDYKNALQIFIK-VRETIQDAHVYVNM 779 Query: 642 GMIYYKQEKFSLAEMHFQKAL--DINPQSS-------VLLCHIGVVQHALKKSEKALDTL 692 G IY + +FS A ++ AL + + + G + L + ALD Sbjct: 780 GHIYAELRQFSKAIESYEIALSKEGKANDAGIISCLGRTWLNKGRAERNLDAYKMALDQA 839 Query: 693 NKAIVIDPKNPLCKFHRASV 712 KA+ + P KF+ A V Sbjct: 840 KKAVAVAPDQLHFKFNVAFV 859 Score = 44.8 bits (104), Expect = 2e-04, Method: Composition-based stats. Identities = 24/125 (19%), Positives = 43/125 (34%), Gaps = 13/125 (10%) Query: 640 GLGMIYYKQEKFSLAEMHFQKALD-------------INPQSSVLLCHIGVVQHALKKSE 686 +G Y ++ K LA FQ ALD I+ + + ++G + Sbjct: 536 NIGCFYSQEGKHRLATEFFQAALDSCARISQTENDLDIDALLTTIPFNLGRSYEYEGDID 595 Query: 687 KALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKV 746 KA++T + + + A + K + +L Q P + V L G Sbjct: 596 KAIETYEQLLSRHSDYTDARTRLAYIKLRRNPNKEGPDAVAKLYQENPSDLEVRGLYGWF 655 Query: 747 YKKLG 751 K+ Sbjct: 656 LSKVN 660 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 35/217 (16%), Positives = 70/217 (32%), Gaps = 35/217 (16%) Query: 506 GRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDM--- 562 + + A + F E R+ R L + K AL L + + Sbjct: 165 AVDSNKAEQLRNALKSFEEAIRVSQGR--------NMLAVMGKARALFSLGRYPESLAAY 216 Query: 563 --------DKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLG------ 608 D P+ G CF D A ++R ++++P+ +A LLG Sbjct: 217 QDVVAKMPDMVDPDPRIGIGCCFWQLGFKDDAKIAWERCLEINPDSKHANILLGLYYLDA 276 Query: 609 ------HEFVLTEELDKALACFR-NAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 661 + KA+ + + +++ + +++F + KA Sbjct: 277 SGHVPTNSPEFIRLYKKAMTEYTQKSFKLDKNLPLTCATFAGYFLSRKQFGNVDALAHKA 336 Query: 662 LD---INPQSSVLLCHIGVVQHALKKSEKALDTLNKA 695 + +N +S + +H E+A D +A Sbjct: 337 IQYTDVNAIASDGWYLLARKEHYDGNLERASDYYRRA 373 >6AHD-N nrPDB Length = 941 Score = 60.6 bits (145), Expect = 3e-09, Method: Composition-based stats. Identities = 37/219 (16%), Positives = 81/219 (36%), Gaps = 18/219 (8%) Query: 536 MEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595 + + + ++K +L K + + + + P AW A+ + + +A + + Sbjct: 281 IPTHGGDINDIKKA---RLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTE 337 Query: 596 VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655 + P + E + D A A A+R P+ + + + Sbjct: 338 MCPKSEDVWL----EAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAA---ELETDIRAKK 390 Query: 656 MHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFA 715 +KAL+ P S L L++ E A L++A+ P + A Sbjct: 391 RVLRKALEHVPNSVRLW----KAAVELEEPEDARIMLSRAVECCPTSVELWLALA----R 442 Query: 716 NEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTH 754 E Y++A + L + ++ +P + ++ K+ + G T Sbjct: 443 LETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQ 481 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 47/286 (16%), Positives = 98/286 (34%), Gaps = 5/286 (1%) Query: 484 AINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTL 543 A +IL+ + N+ + + E EY +A R+ ++ R M+ Sbjct: 627 ARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKS-VKLE 685 Query: 544 WHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYA 603 W A L ++ ++ P+ W G + + A + + + ++ P+ Sbjct: 686 WVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPL 745 Query: 604 YTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALD 663 + LL +L +A A + NP++ W + Y+ ++A KAL Sbjct: 746 WLLLSRLEEKIGQLTRARAILEKSRLKNPKNPGLWLESVRLEYRAGLKNIANTLMAKALQ 805 Query: 664 INPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSAL 723 P S +L ++ ++ K++D L K +P A + ++ K A Sbjct: 806 ECPNSGILWSEAIFLEARPQRRTKSVDALKK----CEHDPHVLLAVAKLFWSQRKITKAR 861 Query: 724 QELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 + +I + K + G +P+ Sbjct: 862 EWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPR 907 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 30/199 (15%), Positives = 68/199 (34%), Gaps = 3/199 (1%) Query: 559 LTDMDKNSPEAWCAAGNCFSLQREHDIAIK-FFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 + + W A F +++ QRA+ P + + L ++ Sbjct: 566 ALQVFPSKKSVWLRAA-YFEKNHGTRESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDV 624 Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 A + A + NP W + + +++ A KA P + V + + Sbjct: 625 PAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKARSSAPTARVFMKSV-K 683 Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 ++ A D +A+ P + + E + A + + + P + Sbjct: 684 LEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHST 743 Query: 738 LVYFLIGKVYKKLGQTHLA 756 ++ L+ ++ +K+GQ A Sbjct: 744 PLWLLLSRLEEKIGQLTRA 762 Score = 45.2 bits (105), Expect = 1e-04, Method: Composition-based stats. Identities = 45/325 (13%), Positives = 84/325 (25%), Gaps = 53/325 (16%) Query: 487 ILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHL 546 +++ H L Q R Y +E R V R V L Sbjct: 361 VVAQAVRH-------LPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVRLWKAAVEL 413 Query: 547 QKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYT- 605 ++ ++ + S E W A ++ A K +A + P + + Sbjct: 414 EEPEDARIMLSRAVECCPTSVELWLALARL----ETYENARKVLNKARENIPTDRHIWIT 469 Query: 606 ------LLGHEFVLTEELDKALACFR-------------------NAIRVNPRHY--NAW 638 G+ ++ + +D+A+ R A V A Sbjct: 470 AAKLEEANGNTQMVEKIIDRAITSLRANGVEINREQWIQDAEECDRAGSVATCQAVMRAV 529 Query: 639 YGLGMIYYK-------------QEKFSLAEMH-FQKALDINPQSSVLLCHIGVVQHALKK 684 G+G+ + AL + P + + Sbjct: 530 IGIGIEEEDRKHTWMEDADSCVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGT 589 Query: 685 SEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 E L +A+ PK + A + +A L Q P ++ Sbjct: 590 RESLEALLQRAVAHCPKAEVLWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAV 649 Query: 745 KVYKKLGQTHLALMNFSWAMDLDPK 769 K+ + + A + A P Sbjct: 650 KLESENDEYERARRLLAKARSSAPT 674 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 48/298 (16%), Positives = 97/298 (32%), Gaps = 25/298 (8%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENY-------RVEGMEIYSTT-LWHLQKDVALSVL 555 ++ A L Y A ++ ++ R + E T + D A++ L Sbjct: 435 ELWLALARLETYENARKVLNKARENIPTDRHIWITAAKLEEANGNTQMVEKIIDRAITSL 494 Query: 556 SKDLTDMD----KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNY-AYAYTLLGHE 610 + +++ E AG+ + Q A+ I ++ + + Sbjct: 495 RANGVEINREQWIQDAEECDRAGSVATCQ-----AVMRAVIGIGIEEEDRKHTWMEDADS 549 Query: 611 FVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV 670 V L+ A A + A++V P + W E Q+A+ P++ V Sbjct: 550 CVAHNALECARAIYAYALQVFPSKKSVWLRAAYFEKNHGTRESLEALLQRAVAHCPKAEV 609 Query: 671 LLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELK 730 L + A L A +P + + N++Y+ A + L + + Sbjct: 610 LWLMGAKSKWLAGDVPAARSILALAFQANPNSEEIWLAAVKLESENDEYERARRLLAKAR 669 Query: 731 QIVP------KESLVYFLIGKVYKKLGQTHLALMNFSWAMDL-DPKGANNQIKEAIDK 781 P K + ++ + AL ++ L KG + KE ++K Sbjct: 670 SSAPTARVFMKSVKLEWVQDNIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEK 727 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 26/247 (10%), Positives = 76/247 (30%), Gaps = 20/247 (8%) Query: 480 NCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENY------RV 533 N + A ++ H+ + + G+ + +A +++ + + + Sbjct: 690 NIRAAQDLCEEALRHYEDFPKLWMMKGQIEEQKEMMEKAREAYNQGLKKCPHSTPLWLLL 749 Query: 534 EGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRA 593 +E L + + S L + +P W + +IA +A Sbjct: 750 SRLEEKIGQLTRARAILEKSRLK------NPKNPGLWLESVRLEYRAGLKNIANTLMAKA 803 Query: 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAW--YGLGMIYYKQEKF 651 +Q PN ++ + K++ + ++ + +++ Q K Sbjct: 804 LQECPNSGILWSEAIFLEARPQRRTKSVDA------LKKCEHDPHVLLAVAKLFWSQRKI 857 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRAS 711 + A F + + I+ + E+ + + +P++ + Sbjct: 858 TKAREWFHRTVKIDSDLGDAWAFFYKFELQHGTEEQQEEVRKRCESAEPRHGELWCAVSK 917 Query: 712 VLFANEK 718 + +K Sbjct: 918 DIANWQK 924 Score = 35.9 bits (81), Expect = 0.071, Method: Composition-based stats. Identities = 22/139 (15%), Positives = 43/139 (30%), Gaps = 2/139 (1%) Query: 646 YKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705 A + + + NP ++ K + A + + K + PK+ Sbjct: 286 GDINDIKKARLLLKSVRETNPHHPPAWIASARLEEVTGKLQVARNLIMKGTEMCPKSEDV 345 Query: 706 KFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMD 765 A + + Q + L Q V L + K AL + ++ Sbjct: 346 WLEAARLQPGDTAKAVVAQAVRHLPQSVRIYIRAAELETDIRAKKRVLRKALEHVPNSVR 405 Query: 766 LDPKGANNQIKEAIDKRYL 784 L A +++E D R + Sbjct: 406 L--WKAAVELEEPEDARIM 422 >5XJC-J nrPDB Length = 848 Score = 58.7 bits (140), Expect = 1e-08, Method: Composition-based stats. Identities = 28/199 (14%), Positives = 65/199 (32%), Gaps = 5/199 (2%) Query: 570 WCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIR 629 W +E A ++RA+ VD + + +++ A + AI Sbjct: 245 WIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNRQVNHARNIWDRAIT 304 Query: 630 VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKAL 689 PR WY + + A F++ ++ P+ + K+ ++A Sbjct: 305 TLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEE-QAWHSYINFELRYKEVDRAR 363 Query: 690 DTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESL---VYFLIGKV 746 + +++ P A + + A + E + E + +Y K Sbjct: 364 TIYERFVLVHPD-VKNWIKYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKF 422 Query: 747 YKKLGQTHLALMNFSWAMD 765 + + + + +A+D Sbjct: 423 EENQKEFERVRVIYKYALD 441 Score = 39.4 bits (90), Expect = 0.007, Method: Composition-based stats. Identities = 33/266 (12%), Positives = 80/266 (30%), Gaps = 31/266 (11%) Query: 570 WCAAGNCFSLQ-REHDIAIKFFQRAIQVDP----NYAYAYTLLGHEFVLTEELDKALACF 624 W L+ ++ + + +Q ++++ P +A + L + + L A Sbjct: 537 WINYALYEELEAKDPERTRQVYQASLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRAL 596 Query: 625 RNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK 684 +I P++ + + + +F ++K L+ P++ ++ L Sbjct: 597 GTSIGKCPKNKLFKVYI-ELELQLREFDRCRKLYEKFLEFGPENCTSWIKFAELETILGD 655 Query: 685 SEKALDTLNKAI------------------VIDPKNPLCKFHRASVLFANEKYKSALQEL 726 ++A AI I+ + + L ++ Sbjct: 656 IDRARAIYELAISQPRLDMPEVLWKSYIDFEIEQEETERTRNLYRRLLQRTQHVKVWISF 715 Query: 727 EELKQIVPKESLV------YFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 + + KE + Y K + + LM + + KE +D Sbjct: 716 AQFELSSGKEGSLTKCRQIYEEANKTMRNCEEKEERLMLLESWRSFEEEFGTASDKERVD 775 Query: 781 KRYLPDDEEPITQEEQIMGTDESQES 806 K ++ + G+D E Sbjct: 776 KLMPEKVKKRRKVQTD-DGSDAGWEE 800 Score = 36.3 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 23/149 (15%), Positives = 52/149 (34%), Gaps = 1/149 (0%) Query: 624 FRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 F + IR N + W ++ A +++ALD++ ++ L ++ + Sbjct: 231 FEDNIRKNRTVISNWIKYAQWEESLKEIQRARSIYERALDVDYRNITLWLKYAEMEMKNR 290 Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLI 743 + A + ++AI P+ + + A Q E + P+E + I Sbjct: 291 QVNHARNIWDRAITTLPRVNQFWYKYTYMEEMLGNVAGARQVFERWMEWQPEEQAWHSYI 350 Query: 744 GKVYKKLGQTHLALMNFSWAMDLDPKGAN 772 + + A + + + P N Sbjct: 351 -NFELRYKEVDRARTIYERFVLVHPDVKN 378 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 27/279 (9%), Positives = 81/279 (29%), Gaps = 25/279 (8%) Query: 512 LSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWC 571 L A ++F + + Y ++ + + + + W Sbjct: 323 LGNVAGARQVFERWMEWQP-EEQAWHSYINFELRYKEVDRARTIYERFVLVHP-DVKNWI 380 Query: 572 AAGNCFSLQREHDIAIKFFQRAIQV---DPNYAYAYTLLGHEFVLTEELDKALACFRNAI 628 A K ++RA++ + + Y +E ++ ++ A+ Sbjct: 381 KYARFEEKHAYFAHARKVYERAVEFFGDEHMDEHLYVAFAKFEENQKEFERVRVIYKYAL 440 Query: 629 -RVNPRHYNAWYGLGMIYYKQEKFSLAEM---------HFQKALDINPQSSVLLCHIGVV 678 R++ + + I+ K+ +++ + NP + + Sbjct: 441 DRISKQDAQELFKNYTIFEKKFGDRRGIEDIIVSKRRFQYEEEVKANPHNYDAWFDYLRL 500 Query: 679 QHALKKSEKALDTLNKAIVIDP---------KNPLCKFHRASVLFANEKYKSALQELEEL 729 + ++E + +AI P + + A K +++ + Sbjct: 501 VESDAEAEAVREVYERAIANVPPIQEKRHWKRYIYLWINYALYEELEAKDPERTRQVYQA 560 Query: 730 -KQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLD 767 +++P + + + +Y + L A+ Sbjct: 561 SLELIPHKKFTFAKMWILYAQFEIRQKNLSLARRALGTS 599 >4UZY-A nrPDB Length = 651 Score = 57.9 bits (138), Expect = 2e-08, Method: Composition-based stats. Identities = 31/224 (13%), Positives = 79/224 (35%), Gaps = 32/224 (14%) Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH 657 P YT + + ++ +A+ + ++ P A LG YY ++ +A Sbjct: 14 PIAEGQYTQTIYTLIKEQKFAEAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQM 73 Query: 658 FQKALDINPQSSVLLCHIGVVQHALKKSEKA------LDTLNKAIVI------------- 698 +++ + + P + + + +A ++ KA+ Sbjct: 74 YEQLVTLYPSNEDYKLYYAQSLYKGGMYPEASKAVVKVEGHQKAVTTLLVACSYEQDDLT 133 Query: 699 ---------DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKK 749 P++P + ++F K+++A Q+ + Q + + + + I Y K Sbjct: 134 GCRRQLDKCAPEDPDTMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIALCYYK 193 Query: 750 LGQTHLALMNF----SWAMDLDPKGANNQIKEAIDKRYLPDDEE 789 Q AL + A+ P+ + + ++ R + + + Sbjct: 194 TKQFGPALKHLAEIIEKAVREHPELSVGSNTDGMEVRSVGNSQT 237 Score = 38.6 bits (88), Expect = 0.012, Method: Composition-based stats. Identities = 36/214 (16%), Positives = 77/214 (35%), Gaps = 10/214 (4%) Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTT 542 EAI L + + + L +G Y+ +Y A +++ ++ + + Y+ + Sbjct: 35 EAIQHLQYQLQNVPESRAALSLLGYCYYYTGQYDMASQMYEQLVTLYPSNEDYKLYYAQS 94 Query: 543 LWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAY 602 L+ SK + ++ + C Q + + + DP Sbjct: 95 LYKGGMYPEA---SKAVVKVEGHQKAVTTLLVACSYEQDDLTGCRRQLDKCAPEDP---D 148 Query: 603 AYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMH----F 658 G + + A F +A++ Y + + YYK ++F A H Sbjct: 149 TMVNTGCIMFKEGKFEAARQKFNDAVQALGYQPELLYNIALCYYKTKQFGPALKHLAEII 208 Query: 659 QKALDINPQSSVLLCHIGVVQHALKKSEKALDTL 692 +KA+ +P+ SV G+ ++ S+ +T Sbjct: 209 EKAVREHPELSVGSNTDGMEVRSVGNSQTLKETA 242 >5OJF-A nrPDB Length = 314 Score = 57.5 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 38/267 (14%), Positives = 92/267 (34%), Gaps = 49/267 (18%) Query: 577 FSLQREHDIAIKFFQRAIQ-VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV----- 630 ++ Q +++A+ ++A++ ++ + + + + + + +++A + Sbjct: 38 YASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAAHLLNDAL 97 Query: 631 ----------NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN--------PQSSVLL 672 +P L ++Y K+ K+ AE ++AL+I P + L Sbjct: 98 AIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQL 157 Query: 673 CHIGVVQHALKKSEKALDTLNKAIVI--------DPKNPLCKFHRASVLFANEKYKSALQ 724 ++ ++ K+E+ +A+ I DP K + AS KY+ A Sbjct: 158 SNLALLCQNQGKAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAET 217 Query: 725 ELEELKQIVPKESLVYFLIGK---VYKKLGQTHLALMN------------FSWAMDLDPK 769 +E+ E + G+ ++ + + + A +D Sbjct: 218 LYKEILT-RAHEKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSP 276 Query: 770 GANNQIKEAIDK-RYLPDDEEPITQEE 795 N ++ R E T E+ Sbjct: 277 TVNTTLRSLGALYRRQGKLEAAHTLED 303 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 11/110 (10%), Positives = 32/110 (29%), Gaps = 16/110 (14%) Query: 502 LCQIGRAYFELSEYMQAERIFSEVRRI--------ENYRVEGMEIYSTTLWHLQKDVALS 553 L + Y + +Y +AE + I + + + + K + Sbjct: 115 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVE 174 Query: 554 VLSKDLTDMD--------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595 + ++ N + +C+ Q ++ A ++ + Sbjct: 175 YYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILT 224 >5UDI-A nrPDB Length = 479 Score = 57.1 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 36/236 (15%), Positives = 86/236 (36%), Gaps = 19/236 (8%) Query: 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626 EA ++ ++ ++ ++D +A G + ++A ACF Sbjct: 113 AEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGG-----KNYERAKACFEK 167 Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHF--------QKALDINPQSSVLLCHIGVV 678 + V+P + + G + Y+ + F LA + ++A+ +NP + + + + Sbjct: 168 VLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALK 227 Query: 679 QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESL 738 + + + +A+ + A AL+ L++ Q P L Sbjct: 228 LQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQETPTSVL 287 Query: 739 VYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQE 794 ++ IG YK ++ A P+G N + + + + + E + ++ Sbjct: 288 LHHQIGLCYKAQ------MIQIKEATKGQPRGQNREKLDKMIRSAIFHFESAVEKK 337 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 28/170 (16%), Positives = 55/170 (32%), Gaps = 18/170 (10%) Query: 500 WVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDL 559 +V + Y +A + + + V + + Q K+ Sbjct: 253 YVFRYAAKFYRRKGSVDKALELLKKALQETPTSVL-LHHQIGLCYKAQMIQI-----KEA 306 Query: 560 TDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDK 619 T N L + AI F+ A++ P + A+ L ++ K Sbjct: 307 TKGQPRGQ-------NREKLDKMIRSAIFHFESAVEKKPTFEVAHLDLARMYIEAGNHRK 359 Query: 620 ALACFRNAIRVNP----RHYNAWYGLGMIYYKQEKFSL-AEMHFQKALDI 664 A F+ + + P + + G Q+K + A +H+ KA+ I Sbjct: 360 AEENFQKLLCMKPVVEETMQDIHFHYGRFQEFQKKSDVNAIIHYLKAIKI 409 >5WQL-B nrPDB Length = 278 Score = 56.7 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 40/248 (16%), Positives = 86/248 (34%), Gaps = 15/248 (6%) Query: 563 DKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALA 622 D + G + +A F +A+ + P+ + LG D A Sbjct: 42 DDERAQLLYERGVLYDSLGLRALARNDFSQALAIRPDMPEVFNYLGIYLTQAGNFDAAYE 101 Query: 623 CFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSV--LLCHIGVVQH 680 F + + ++P + A G+ Y + LA+ +P L ++ + Sbjct: 102 AFDSVLELDPTYNYAHLNRGIALYYGGRDKLAQDDLLAFYQDDPNDPFRSLWLYLAEQKL 161 Query: 681 ALKKSEKAL-DTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQ-ELEELKQIVPKESL 738 K++++ L K+ + +F+ ++ + + L+ + + + S Sbjct: 162 DEKQAKEVLKQHFEKSDKEQWGWNIVEFYLGNI--SEQTLMERLKADATDNTSLAEHLSE 219 Query: 739 VYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIM 798 F +GK Y LG A F A+ N + ++ RY + + Q++ Sbjct: 220 TNFYLGKYYLSLGDLDSATALFKLAVA-------NNVHNFVEHRYALLELSLLGQDQD-- 270 Query: 799 GTDESQES 806 ES + Sbjct: 271 DLAESDQQ 278 >3NF1-A nrPDB Length = 311 Score = 56.7 bits (135), Expect = 4e-08, Method: Composition-based stats. Identities = 29/184 (15%), Positives = 58/184 (31%), Gaps = 24/184 (13%) Query: 641 LGMIYYKQEKFSLAEMHFQKALDIN--------PQSSVLLCHIGVVQHALKKSEKALDTL 692 L ++Y Q K+ A AL I P + L ++ V+ K ++A Sbjct: 75 LALVYRDQNKYKDAANLLNDALAIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLC 134 Query: 693 NKAIVID--------PKNPLCKFHRASVLFANEKYKSALQELEELKQIV--------PKE 736 +A+ I P + A + KY+ + +I P Sbjct: 135 KRALEIREKVLGKDHPDVAKQLNNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNV 194 Query: 737 SLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQ 796 + + Y K G+ A + + + + + ++ +E + +Q Sbjct: 195 AKTKNNLASCYLKQGKFKQAETLYKEILTRAHEREFGSVDDENKPIWMHAEEREECKGKQ 254 Query: 797 IMGT 800 GT Sbjct: 255 KDGT 258 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 71/186 (38%), Gaps = 32/186 (17%) Query: 577 FSLQREHDIAIKFFQRAIQ-VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV----- 630 ++ Q +++A+ ++A++ ++ + + + + + + +++A + Sbjct: 37 YASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDAL 96 Query: 631 ----------NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN--------PQSSVLL 672 +P L ++Y K+ K+ AE ++AL+I P + L Sbjct: 97 AIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQL 156 Query: 673 CHIGVVQHALKKSEKALDTLNKAIVI--------DPKNPLCKFHRASVLFANEKYKSALQ 724 ++ ++ K E+ +A+ I DP K + AS K+K A Sbjct: 157 NNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAET 216 Query: 725 ELEELK 730 +E+ Sbjct: 217 LYKEIL 222 >4JHR-A nrPDB Length = 333 Score = 56.0 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 33/259 (12%), Positives = 79/259 (30%), Gaps = 50/259 (19%) Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNP------RHYNAWYGLGMIYYKQEKFS-- 652 A A LG+ + D+A+ C + + ++ A Y LG +Y+ + K Sbjct: 11 AKASGNLGNTLKVLGNFDEAIVCCQRHLDISRELNDKVGEARALYNLGNVYHAKGKSFGC 70 Query: 653 ------------------LAEMHFQ------KALDINPQSSVLLCHIGVVQHALKKSEKA 688 A ++ AL ++G + L A Sbjct: 71 PGPQDTGEFPEDVRNALQAAVDLYEENLSLVTALGDRAAQGRAFGNLGNTHYLLGNFRDA 130 Query: 689 LDTLNKAIVIDPKNPL------CKFHRASVLFANEKYKSALQELEELKQIVPK------E 736 + + ++I + + + ++++A + ++ + + E Sbjct: 131 VIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASEYYKKTLLLARQLKDRAVE 190 Query: 737 SLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQ 796 + + +G Y L A+ + + + + I E L + + +Q Sbjct: 191 AQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDR-IGEGRACWSLGNAYTALGNHDQ 249 Query: 797 IM-----GTDESQESSMTD 810 M + S+E + Sbjct: 250 AMHFAEKHLEISREVGDLE 268 Score = 49.4 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 54/148 (36%), Gaps = 18/148 (12%) Query: 569 AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAY------AYTLLGHEFVLTEELDKALA 622 A+ GN L A+ ++ + + + AY+ LG+ ++ E + A Sbjct: 113 AFGNLGNTHYLLGNFRDAVIAHEQRLLIAKEFGDKAAERRAYSNLGNAYIFLGEFETASE 172 Query: 623 CFRN----AIRVNPRHYNAW--YGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCH-- 674 ++ A ++ R A Y LG Y + + A + K L I + + Sbjct: 173 YYKKTLLLARQLKDRAVEAQSCYSLGNTYTLLQDYEKAIDYHLKHLAIAQELKDRIGEGR 232 Query: 675 ----IGVVQHALKKSEKALDTLNKAIVI 698 +G AL ++A+ K + I Sbjct: 233 ACWSLGNAYTALGNHDQAMHFAEKHLEI 260 >4ABN-A nrPDB Length = 474 Score = 56.0 bits (133), Expect = 6e-08, Method: Composition-based stats. Identities = 43/222 (19%), Positives = 84/222 (37%), Gaps = 22/222 (9%) Query: 579 LQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD-KALACFRNAIRVNPRHYNA 637 +Q E + ++ + + A A L G +T + +A A+++ P A Sbjct: 80 VQEEMEKTLQQMEEVLGSAQVEAQALMLKGKALNVTPDYSPEAEVLLSKAVKLEPELVEA 139 Query: 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKK------SEKALDT 691 W LG +Y+K+ + A F AL + ++ V L ++ +V L+ S +D+ Sbjct: 140 WNQLGEVYWKKGDVTSAHTCFSGALT-HCKNKVSLQNLSMVLRQLQTDSGDEHSRHVMDS 198 Query: 692 LNKA--------IVIDPKNPLCK------FHRASVLFANEKYKSALQELEELKQIVPKES 737 + +A + L F+ +++ SA + E++ + Sbjct: 199 VRQAKLAVQMDVLDGRSWYILGNAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKASSNP 258 Query: 738 LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAI 779 ++ ++K AL FS A LDP Q +E Sbjct: 259 DLHLNRATLHKYEESYGEALEGFSQAAALDPAWPEPQQREQQ 300 Score = 54.0 bits (128), Expect = 3e-07, Method: Composition-based stats. Identities = 45/273 (16%), Positives = 90/273 (32%), Gaps = 42/273 (15%) Query: 507 RAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDK-N 565 +YFE A R +V+ ++ ME + + + +L ++ Sbjct: 62 DSYFETHSVEDAGRKQQDVQEEMEKTLQQMEEVLGSAQVEAQAL---MLKGKALNVTPDY 118 Query: 566 SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFR 625 SPE A +A++++P A+ LG + ++ A CF Sbjct: 119 SPE-----------------AEVLLSKAVKLEPELVEAWNQLGEVYWKKGDVTSAHTCFS 161 Query: 626 NAIRVNPRHYNAWYGLGMIYYKQ------EKFSLAEMHFQK---ALDINPQSSVLLCHIG 676 A+ + L M+ + E ++ A+ ++ +G Sbjct: 162 GALTHCKNK-VSLQNLSMVLRQLQTDSGDEHSRHVMDSVRQAKLAVQMDVLDGRSWYILG 220 Query: 677 VVQHAL--------KKSEKALDTLNKAIVID---PKNPLCKFHRASVLFANEKYKSALQE 725 +L K S++AL +A +D NP +RA++ E Y AL+ Sbjct: 221 NAYLSLYFNTGQNPKISQQALSAYAQAEKVDRKASSNPDLHLNRATLHKYEESYGEALEG 280 Query: 726 LEELKQIVPKESLVYFLIGKVYKKLGQTHLALM 758 + + P ++ + L + L Sbjct: 281 FSQAAALDPAWPEPQQREQQLLEFLSRLTSLLE 313 >3JCM-G nrPDB Length = 899 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 43/247 (17%), Positives = 83/247 (33%), Gaps = 15/247 (6%) Query: 499 GWVLCQIGRAYFELSEYMQAERIFSEVRRIENYR-VEGMEI------YSTTLWHLQKDVA 551 + + R Y++ +++ + + E + N R ++ I ++H ++ Sbjct: 626 DFKISGTERLYYKYVNFLRYQDLNEEAIKFLNERCLKSFPICHKFFLQLGQIYHSMGNIE 685 Query: 552 LS---VLSKDLTDMDKNSPEAWCAAGNCFSL-QREHDIAIKFFQRAIQVDPNYAYAYTLL 607 +S LS T + N P W + + + A R + +P+ Y Sbjct: 686 MSRETYLSG--TRLVPNCPLLWVSLSKIDEIDLKNPVRARSILDRGLLKNPDDVLFYIAK 743 Query: 608 GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 + LD+A A++ P + W ++ K SL + FQ AL Sbjct: 744 IQMEIRLGNLDQAELLVTQALQKFPSNALLWVEQIKLFKHGNKSSLKKTIFQDALRRTQN 803 Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELE 727 +L IGV +A + E +L L +A+ + K + Sbjct: 804 DHRVLLEIGVSFYAEAQYETSLKWLERALKKCSRYGDTWVWLFRTYARLGK--DTVDLYN 861 Query: 728 ELKQIVP 734 Q P Sbjct: 862 MFDQCEP 868 Score = 37.5 bits (85), Expect = 0.023, Method: Composition-based stats. Identities = 29/182 (15%), Positives = 58/182 (31%), Gaps = 15/182 (8%) Query: 587 IKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYY 646 +K +++A DP + + A N + PR + W ++ Sbjct: 230 LKSYRKA---DPTNPQGWIASARLEEKARKFSVAKKIIENGCQECPRSSDIWLENIRLHE 286 Query: 647 KQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCK 706 + A++ NP S +L + K + KA+ P++ Sbjct: 287 --SDVHYCKTLVATAINFNPTSPLLW--FKAIDLESTTVNKY-RVVRKALQEIPRD-EGL 340 Query: 707 FHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 + A + ++ LE+ Q +P+ + Y L H A M + + Sbjct: 341 WKLA--VSFEADKAQVIKMLEKATQFIPQSMDLLT----AYTNLQSYHNAKMTLNSFRKI 394 Query: 767 DP 768 P Sbjct: 395 LP 396 >2C2L-A nrPDB Length = 281 Score = 55.2 bits (131), Expect = 1e-07, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 45/94 (47%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 GN + R++ A + RAI +P A YT ++ ++ ++ALA R A+ ++ + Sbjct: 11 GNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQ 70 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 A + LG + E + A + Q+A + + Sbjct: 71 SVKAHFFLGQCQLEMESYDEAIANLQRAYSLAKE 104 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 20/91 (21%), Positives = 42/91 (46%) Query: 608 GHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ 667 G+ + + +A AC+ AI NP + + Y K ++ A ++AL+++ Q Sbjct: 11 GNRLFVGRKYPEAAACYGRAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQ 70 Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698 S +G Q ++ ++A+ L +A + Sbjct: 71 SVKAHFFLGQCQLEMESYDEAIANLQRAYSL 101 Score = 39.0 bits (89), Expect = 0.009, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 30/75 (40%) Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 + + C+ ++ + A+ +RA+++D A+ LG + E Sbjct: 29 RAITRNPLVAVYYTNRALCYLKMQQPEQALADCRRALELDGQSVKAHFFLGQCQLEMESY 88 Query: 618 DKALACFRNAIRVNP 632 D+A+A + A + Sbjct: 89 DEAIANLQRAYSLAK 103 >5OJ8-A nrPDB Length = 255 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 71/186 (38%), Gaps = 32/186 (17%) Query: 577 FSLQREHDIAIKFFQRAIQ-VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV----- 630 ++ Q +++A+ ++A++ ++ + + + + + + +++A + Sbjct: 60 YASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDAL 119 Query: 631 ----------NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN--------PQSSVLL 672 +P L ++Y K+ K+ AE ++AL+I P + L Sbjct: 120 AIREKTLGKDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQL 179 Query: 673 CHIGVVQHALKKSEKALDTLNKAIVI--------DPKNPLCKFHRASVLFANEKYKSALQ 724 ++ ++ K E+ +A+ I DP K + AS K+K A Sbjct: 180 NNLALLCQNQGKYEEVEYYYQRALEIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAET 239 Query: 725 ELEELK 730 +E+ Sbjct: 240 LYKEIL 245 >5ZYQ-A nrPDB Length = 320 Score = 54.8 bits (130), Expect = 2e-07, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 80/235 (34%), Gaps = 30/235 (12%) Query: 483 EAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIEN--YR------VE 534 E ++S L H + + Y++ + + ++ R N YR + Sbjct: 26 EGDEVISILKQEHTQL-HIWIALALEYYKQGKTEEFVKLLEAARIDGNLDYRDHEKDQMT 84 Query: 535 GMEIYSTTLWHLQKDVA--------------LSVLSKDLTDMDKNSPEAWCAAGNCFSLQ 580 ++ + + L ++ + D+N CF L Sbjct: 85 CLDTLAAYYVQQARKEKNKDNKKDLITQATLLYTMADKIIMYDQNH----LLGRACFCLL 140 Query: 581 RE--HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRH-YNA 637 D A F + PN A ++ ALA ++ A+R NP Sbjct: 141 EGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPAEV 200 Query: 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTL 692 G+G + K K A + F +AL++N + L + V++ K+++ + + Sbjct: 201 RLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEADGSENLY 255 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 24/111 (21%), Positives = 49/111 (44%), Gaps = 1/111 (0%) Query: 611 FVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSS- 669 + +++D+A A F + +P + A G I + ++ + A +++KAL NP Sbjct: 139 LLEGDKMDQADAQFHFVLNQSPNNIPALLGKACISFNKKDYRGALAYYKKALRTNPGCPA 198 Query: 670 VLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 + +G L K EKA ++A+ ++ K A + N++ Sbjct: 199 EVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLELNNKEAD 249 Score = 36.3 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 44/135 (32%), Gaps = 5/135 (3%) Query: 496 YNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDV---AL 552 Y+ +L + E + QA+ F V + + K AL Sbjct: 126 YDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPAL--LGKACISFNKKDYRGAL 183 Query: 553 SVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFV 612 + K L E G+CF + + A F RA++++ A L + Sbjct: 184 AYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALELNSKCVGALVGLAVLEL 243 Query: 613 LTEELDKALACFRNA 627 +E D + + + Sbjct: 244 NNKEADGSENLYFQS 258 Score = 34.0 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 23/141 (16%), Positives = 43/141 (30%), Gaps = 4/141 (2%) Query: 617 LDKALACFRNAIRVNPRHYNAWYGLGM-IYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 + +A + A ++ N G + +K A+ F L+ +P + L Sbjct: 110 ITQATLLYTMADKIIMYDQNHLLGRACFCLLEGDKMDQADAQFHFVLNQSPNNIPALLGK 169 Query: 676 GVVQHALKKSEKALDTLNKAIVIDPKNP-LCKFHRASVLFANEKYKSALQELEELKQIVP 734 + K AL KA+ +P P + K + A ++ Sbjct: 170 ACISFNKKDYRGALAYYKKALRTNPGCPAEVRLGMGHCFVKLNKLEKARLAFSRALEL-- 227 Query: 735 KESLVYFLIGKVYKKLGQTHL 755 V L+G +L Sbjct: 228 NSKCVGALVGLAVLELNNKEA 248 >4G1T-A nrPDB Length = 472 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 29/199 (14%), Positives = 69/199 (34%), Gaps = 17/199 (8%) Query: 568 EAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTE----------EL 617 W + + + V ++ Y + E E + Sbjct: 95 VTWGNYAWVYYHMGRLSDVQIYVDKVKHVCEKFSSPYRIESPELDCEEGWTRLKCGGNQN 154 Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFS---LAEMHFQKALDINPQSSVLLCH 674 ++A CF A+ P++ GL + Y+ + + A ++A+ +NP + L Sbjct: 155 ERAKVCFEKALEKKPKNPEFTSGLAIASYRLDNWPPSQNAIDPLRQAIRLNPDNQYLKVL 214 Query: 675 IGVVQHALKKSEKALDTLNK----AIVIDPKNPLCKFHRASVLFANEKYKSALQELEELK 730 + + H +++ + K A+ P A ++ A++ L++ Sbjct: 215 LALKLHKMREEGEEEGEGEKLVEEALEKAPGVTDVLRSAAKFYRRKDEPDKAIELLKKAL 274 Query: 731 QIVPKESLVYFLIGKVYKK 749 + +P + ++ IG Y+ Sbjct: 275 EYIPNNAYLHCQIGCCYRA 293 Score = 46.3 bits (108), Expect = 6e-05, Method: Composition-based stats. Identities = 44/243 (18%), Positives = 85/243 (34%), Gaps = 31/243 (12%) Query: 459 AEGLMSLLREMGKGYLALCSYNCKEAINILSHLPSHHYNTGWVLCQIGRAYFELSEYMQA 518 A G+ +LR K Y +AI +L + N ++ CQIG Y Sbjct: 243 APGVTDVLRSAAKFYRR--KDEPDKAIELLKKALEYIPNNAYLHCQIGCCY--------R 292 Query: 519 ERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFS 578 ++F + EN GM Y A++ L K + + N + + Sbjct: 293 AKVFQVMNLREN----GM--YGKRKLLELIGHAVAHL-KKADEANDNLFRVCSILASLHA 345 Query: 579 LQREHDIAIKFFQRAIQVDPNYAYAYTL---LGH-EFVLTEELDKALACFRNAIRVNPRH 634 L +++ A +FQ+ + L G+ + + DKA+ F +++N Sbjct: 346 LADQYEEAEYYFQKEFSKELTPVAKQLLHLRYGNFQLYQMKCEDKAIHHFIEGVKINQ-- 403 Query: 635 YNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNK 694 K++ + + L N S L + +Q +K ++A + + Sbjct: 404 --------KSREKEKMKDKLQKIAKMRLSKNGADSEALHVLAFLQELNEKMQQADEDSER 455 Query: 695 AIV 697 + Sbjct: 456 GLE 458 >3ZFW-A nrPDB Length = 263 Score = 54.0 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 34/196 (17%), Positives = 65/196 (33%), Gaps = 33/196 (16%) Query: 632 PRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN--------PQSSVLLCHIGVVQHALK 683 P L ++Y K+ K+ AE ++AL+I P + L ++ ++ Sbjct: 62 PAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQG 121 Query: 684 KSEKALDTLNKAIVI--------DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPK 735 K+E+ +A+ I DP K + AS KY+ A +E+ Sbjct: 122 KAEEVEYYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILT-RAH 180 Query: 736 ESLVYFLIGK---VYKKLGQTHLALMN------------FSWAMDLDPKGANNQIKEAID 780 E + G+ ++ + + + A +D N ++ Sbjct: 181 EKEFGSVNGENKPIWMHAEEREESKDKRRDSAPYGEYGSWYKACKVDSPTVNTTLRSLGA 240 Query: 781 K-RYLPDDEEPITQEE 795 R E T E+ Sbjct: 241 LYRRQGKLEAAHTLED 256 Score = 31.3 bits (69), Expect = 2.0, Method: Composition-based stats. Identities = 11/110 (10%), Positives = 32/110 (29%), Gaps = 16/110 (14%) Query: 502 LCQIGRAYFELSEYMQAERIFSEVRRI--------ENYRVEGMEIYSTTLWHLQKDVALS 553 L + Y + +Y +AE + I + + + + K + Sbjct: 68 LNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKFHPDVAKQLSNLALLCQNQGKAEEVE 127 Query: 554 VLSKDLTDMD--------KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQ 595 + ++ N + +C+ Q ++ A ++ + Sbjct: 128 YYYRRALEIYATRLGPDDPNVAKTKNNLASCYLKQGKYQDAETLYKEILT 177 >4ZLH-A nrPDB Length = 339 Score = 52.9 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 35/219 (15%), Positives = 76/219 (34%), Gaps = 14/219 (6%) Query: 583 HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVN----PRHYNAW 638 D A+ F ++ D A+ LG+ F E+D+A+ + + + A Sbjct: 1 QDKAVDLFLDMLKEDTGTVEAHLTLGNLFRSRGEVDRAIRIHQTLMESASLTYEQRLLAI 60 Query: 639 YGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698 LG Y + AE F + D L + + A + +KA+D + + + Sbjct: 61 QQLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKL 120 Query: 699 DPK-------NPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLG 751 + C+ + A+ L++ + V ++G+V+ G Sbjct: 121 GKDKQRVEIAHFYCELALQHMASD--DLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKG 178 Query: 752 QTHLALMNFSWAMDLDPKGANNQIKEAID-KRYLPDDEE 789 + A+ + + D + + ++ + L E Sbjct: 179 EYAKAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAE 217 Score = 52.1 bits (123), Expect = 9e-07, Method: Composition-based stats. Identities = 41/236 (17%), Positives = 86/236 (36%), Gaps = 13/236 (5%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDM- 562 Q+GR Y Y +AE +F+++ ++R+ ++ + +++ L + Sbjct: 62 QLGRDYMAAGLYDRAEDMFNQLTDETDFRIGALQQLLQIYQATSEWQKAIDVAERLVKLG 121 Query: 563 -DKNSPE---AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELD 618 DK E +C + D A+ ++ D N A ++G F+ E Sbjct: 122 KDKQRVEIAHFYCELALQHMASDDLDRAMTLLKKGAAADKNSARVSIMMGRVFMAKGEYA 181 Query: 619 KALACFRNAIRVNPRHYNAWYG-LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 KA+ + I + + L Y + K + Q+A++ N + + Sbjct: 182 KAVESLQRVISQDRELVSETLEMLQTCYQQLGKTAEWAEFLQRAVEEN-TGADAELMLAD 240 Query: 678 VQHALKKSEKALDTLNKAIVIDPK----NPLCKFHRASVLFANEKYKSALQELEEL 729 + A SE A + + + P + L +H + K +L L ++ Sbjct: 241 IIEARDGSEAAQVYITRQLQRHPTMRVFHKLMDYHLNEA--EEGRAKESLMVLRDM 294 >1IHG-A nrPDB Length = 370 Score = 52.9 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 26/129 (20%), Positives = 58/129 (44%), Gaps = 16/129 (12%) Query: 639 YGLGMIYYKQEKFSLAEMHFQKAL----------------DINPQSSVLLCHIGVVQHAL 682 +G ++K + + +A + K L + P + + +IG + + Sbjct: 227 KNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKM 286 Query: 683 KKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFL 742 + A+D+ +A+ IDP N + RA ++Y AL +L++ ++I P++ + Sbjct: 287 SDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAE 346 Query: 743 IGKVYKKLG 751 + KV +K+ Sbjct: 347 LLKVKQKIK 355 Score = 48.6 bits (114), Expect = 9e-06, Method: Composition-based stats. Identities = 22/140 (15%), Positives = 51/140 (36%), Gaps = 17/140 (12%) Query: 572 AAGNCFSLQREHDIAIKFFQRAIQ----------------VDPNYAYAYTLLGHEFVLTE 615 GN F + ++AIK + + ++ + P +G + Sbjct: 228 NIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMS 287 Query: 616 ELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHI 675 + A+ A+ ++P + A Y + +++ A +KA +I P+ + + Sbjct: 288 DWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAEL 347 Query: 676 GVVQHALK-KSEKALDTLNK 694 V+ +K + +K K Sbjct: 348 LKVKQKIKAQKDKEKAAYAK 367 Score = 47.5 bits (111), Expect = 3e-05, Method: Composition-based stats. Identities = 24/135 (17%), Positives = 49/135 (36%), Gaps = 16/135 (11%) Query: 606 LLGHEFVLTEELDKALACFRNAIR----------------VNPRHYNAWYGLGMIYYKQE 649 +G+ F ++ + A+ + +R + P + +G K Sbjct: 228 NIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAKLQPVALSCVLNIGACKLKMS 287 Query: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR 709 + A +AL+I+P ++ L LK+ ++AL L KA I P++ + Sbjct: 288 DWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQALADLKKAQEIAPEDKAIQAEL 347 Query: 710 ASVLFANEKYKSALQ 724 V + K + Sbjct: 348 LKVKQKIKAQKDKEK 362 Score = 35.9 bits (81), Expect = 0.068, Method: Composition-based stats. Identities = 28/148 (18%), Positives = 55/148 (37%), Gaps = 5/148 (3%) Query: 507 RAYFELSEYMQAERIFSEVRRIEN--YRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDK 564 A +L + + I +++ I N ++ + E+ + + V S + + D K Sbjct: 208 DADVDLKDVDKILLISEDLKNIGNTFFKSQNWEMAIKKYTKVLRYVEGSRAAAEDADGAK 267 Query: 565 NSPEAW---CAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKAL 621 P A G C + A+ A+++DP+ A + +E D+AL Sbjct: 268 LQPVALSCVLNIGACKLKMSDWQGAVDSCLEALEIDPSNTKALYRRAQGWQGLKEYDQAL 327 Query: 622 ACFRNAIRVNPRHYNAWYGLGMIYYKQE 649 A + A + P L + K + Sbjct: 328 ADLKKAQEIAPEDKAIQAELLKVKQKIK 355 >6FUZ-A nrPDB Length = 337 Score = 52.9 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 29/186 (15%), Positives = 71/186 (38%), Gaps = 32/186 (17%) Query: 577 FSLQREHDIAIKFFQRAIQ-VDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRV----- 630 ++ Q +++A+ ++A++ ++ + + + + + + +++A + Sbjct: 23 YASQGRYEVAVPLCKQALEDLEKTSGHDHPDVATMLNILALVYRDQNKYKDAANLLNDAL 82 Query: 631 ----------NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN--------PQSSVLL 672 +P L ++Y K+ K+ AE ++AL+I P + L Sbjct: 83 AIREKTLGRDHPAVAATLNNLAVLYGKRGKYKEAEPLCKRALEIREKVLGKDHPDVAKQL 142 Query: 673 CHIGVVQHALKKSEKALDTLNKAIVI--------DPKNPLCKFHRASVLFANEKYKSALQ 724 ++ ++ K E+ +A+ I DP K + AS K+K A Sbjct: 143 NNLALLCQNQGKYEEVEYYYQRALGIYQTKLGPDDPNVAKTKNNLASCYLKQGKFKQAET 202 Query: 725 ELEELK 730 +E+ Sbjct: 203 LYKEIL 208 >4I9E-A nrPDB Length = 383 Score = 52.5 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 60/342 (17%), Positives = 109/342 (31%), Gaps = 64/342 (18%) Query: 504 QIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWH------LQKDVALSVLSK 557 I A + E Q E + + Y ME + + LS Sbjct: 27 SIPDAEYLRREIKQELDQMEEDQDLHLYY-SLMEFRHNLMLEYLEPLEKMRIEEQPRLSD 85 Query: 558 DLTDMDKNSPEAWCAAGNCFSL--------QREHDIAIKFFQRAI--------QVDP--- 598 L ++DK F+ QRE+ AIKFF++A +++ Sbjct: 86 LLLEIDKKQARLTGLLEYYFNFFRGMYELDQREYLSAIKFFKKAESKLIFVKDRIEKAEF 145 Query: 599 --NYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEM 656 + +Y + + + +A ++ N R + +++ A Sbjct: 146 FFKMSESYYYMKQTYFSMDYARQAYEIYKEHEAYNIRLLQCHSLFATNFLDLKQYEDAIS 205 Query: 657 HFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFAN 716 HFQKA + ++EK + + + ++ + Sbjct: 206 HFQKAYSMA------------------EAEKQPQLMGRTL----------YNIGLCKNSQ 237 Query: 717 EKYKSALQELEELK------QIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKG 770 +Y+ A+ + I+P YFLI +++ KLG+ A S M K Sbjct: 238 SQYEDAIPYFKRAIAVFEESNILPSLPQAYFLITQIHYKLGKIDKAHEYHSKGMAYSQKA 297 Query: 771 ANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDAD 812 + + + +L EE I G + ES M AD Sbjct: 298 GD--VIYLSEFEFLKSLYLSGPDEEAIQGFFDFLESKMLYAD 337 >5JZ6-A nrPDB Length = 429 Score = 51.0 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 35/200 (17%), Positives = 61/200 (30%), Gaps = 15/200 (7%) Query: 543 LWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDI-------AIKFFQRAIQ 595 L K K+L SP A C E AI+ +Q Sbjct: 22 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVAS 81 Query: 596 VD--PNYAYAYTLLGHEFVL--TEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651 + P +L + +L + +++ P + LG+ Y Sbjct: 82 LPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGDN 141 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI-DP--KNPLCKFH 708 A+ +++ L + P H G + A K +++ L + I DP + FH Sbjct: 142 DNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDDGRFYFH 201 Query: 709 RASVLFANEKYKSALQELEE 728 + K A + E Sbjct: 202 LGDAMQRVGN-KEAYKWYEL 220 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 27/175 (15%), Positives = 57/175 (32%), Gaps = 14/175 (8%) Query: 611 FVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQ-------EKFSLAEMHFQKALD 663 ++++A+ F+ +R P+ A YG E A +Q+ Sbjct: 22 LRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLAEKRRSNEVLRGAIETYQEVAS 81 Query: 664 INPQSSVLLCHIGVV-----QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEK 718 + P L + + Q L +L TL + + + P + K Sbjct: 82 L-PDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQLFPNDTSLKNDLGVGYLLIGD 140 Query: 719 YKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDL-DPKGAN 772 +A + EE+ + P + G + K + ++ ++ DP + Sbjct: 141 NDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIPYLKEGIESGDPGTDD 195 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 29/221 (13%), Positives = 70/221 (31%), Gaps = 18/221 (8%) Query: 556 SKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGH---EFV 612 L + + +A A + + + A+ F+ ++ P A + Sbjct: 1 KPKLLNKFDKTIKAELDAAEKLRKRGKIEEAVNAFKELVRKYPQSPRARYGKAQCEDDLA 60 Query: 613 LTEE----LDKALACFRNAIRV--NPRHYN--AWYGLGMIYYKQEKFSLAEMHFQKALDI 664 L A+ ++ + P + + + Q+ + + Sbjct: 61 EKRRSNEVLRGAIETYQEVASLPDVPADLLKLSLKRRSDRQQFLGHMRGSLLTLQRLVQL 120 Query: 665 NPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQ 724 P + L +GV + ++ A + + + P + K H +L A K ++ Sbjct: 121 FPNDTSLKNDLGVGYLLIGDNDNAKKVYEEVLSVTPNDGFAKVHYGFILKAQNKIAESIP 180 Query: 725 ELEELKQI---VPKESLVYFLIGKVYKKLGQTHLALMNFSW 762 L+E + + YF +G +++G + W Sbjct: 181 YLKEGIESGDPGTDDGRFYFHLGDAMQRVGNKEA----YKW 217 >5O09-1C nrPDB Length = 238 Score = 49.8 bits (117), Expect = 4e-06, Method: Composition-based stats. Identities = 37/228 (16%), Positives = 79/228 (34%), Gaps = 41/228 (17%) Query: 513 SEYMQAERIFSEVRRI---ENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT--------D 561 + A R E RR+ + RV + + L L++ ++ L + Sbjct: 6 RQIASASRSVEEARRLAYHDPIRVGALVEQISVLADLRQKEGDFRKAESLYREALFRAQE 65 Query: 562 MDKNSPE----AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYT--------LLGH 609 + K P+ + + + D A +F++ A+++ + L Sbjct: 66 LRKQDPDLLTGIYSLLAHLYDRWGRMDKAAEFYELALKISAENGLEESDKVATIKNNLAM 125 Query: 610 EFVLTEELDKALACFRNAIRV--------NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKA 661 F + ++A + A+ + R + + LG++YY A++ ++A Sbjct: 126 IFKQLRKFERAEGYYCEALETFQRLDGEQSARVASVYNNLGVLYYSHMDVDRAQVMHERA 185 Query: 662 LDIN----------PQSSVLLCHIGVVQHALKKSEKALDTLNKAIVID 699 L I S ++G V A +KA +++A I Sbjct: 186 LAIRQNLHEGQMDPADLSQTFINLGAVYKAAGDFQKAEACVDRAKRIR 233 >2IF4-A nrPDB Length = 338 Score = 49.4 bits (116), Expect = 6e-06, Method: Composition-based stats. Identities = 21/128 (16%), Positives = 38/128 (29%), Gaps = 18/128 (14%) Query: 608 GHEFVLTEELDKALACFRNAIRVNPRHYN-----------------AWYGLGMIYYKQEK 650 G+ E+L++A+ + AI + + K ++ Sbjct: 186 GNSLFKEEKLEEAMQQYEMAIAYMGDDFMFQLYGKYQDMALAVKNPCHLNIAACLIKLKR 245 Query: 651 FSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRA 710 + A H L ++ L G + L + + A D KA P + Sbjct: 246 YDEAIGHCNIVLTEEEKNPKALFRRGKAKAELGQMDSARDDFRKAQKYAPDD-KAIRREL 304 Query: 711 SVLFANEK 718 L EK Sbjct: 305 RALAEQEK 312 >6FRK-r nrPDB Length = 605 Score = 48.3 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 41/269 (15%), Positives = 90/269 (33%), Gaps = 19/269 (7%) Query: 509 YFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPE 568 Y + ++ +A + +++ +I V + L + T + N+ Sbjct: 21 YGQNGDFTRALKTVNKILQINKDDVTALHCKVVCLIQNGSFKEALNVINTHTKVLANNSL 80 Query: 569 AWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAI 628 + C + A+K + A Q L G E D+ LA +R+ + Sbjct: 81 S-FEKAYCEYRLNRIENALKTIESANQQTDKLKE---LYGQVLYRLERYDECLAVYRDLV 136 Query: 629 RVNPRHYNAW--YGLGMIYYKQEK----FSLAEMHFQKALDINPQSSVLLCHIGVVQHAL 682 R + Y+ L + Q + ++ ++ L G + A+ Sbjct: 137 RNSQDDYDEERKTNLSAVVAAQSNWEKVVPENLGLQEGTHELCYNAACALIGQGQLSQAM 196 Query: 683 KKSEKALDTLNKAI-------VIDPKNPLCKFH--RASVLFANEKYKSALQELEELKQIV 733 K +KA D +++ DP+ L H A +L + + ALQ ++ ++ Sbjct: 197 KILQKAEDLCRRSLSEDSDGTEEDPQAELAIIHGQMAYILQLQGRTEEALQLYNQIIKLK 256 Query: 734 PKESLVYFLIGKVYKKLGQTHLALMNFSW 762 P + + +I + + + Sbjct: 257 PTDVGLLAVIANNIITINKDQNVFDSKKK 285 >6ICZ-I nrPDB Length = 855 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 31/242 (12%), Positives = 71/242 (29%), Gaps = 28/242 (11%) Query: 583 HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNP--RHYNAWYG 640 H+ A F + ++ + + + F A+R P +H W Sbjct: 99 HERAFVFMHKMPRL-------WLDYCQFLMDQGRVTHTRRTFDRALRALPITQHSRIWP- 150 Query: 641 LGMIYYKQEKFSL-AEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAI--- 696 L + + + A +++ L ++P+S+ + + ++A L + Sbjct: 151 LYLRFLRSHPLPETAVRGYRRFLKLSPESAEEYIEY---LKSSDRLDEAAQRLATVVNDE 207 Query: 697 VIDPKNPLCKFHRASVLFAN-EKYKSALQELEE-------LKQIVPKESLVYFLIGKVYK 748 K + L + +Q L L + + ++ + Y Sbjct: 208 RFVSKAGKSNYQLWHELCDLISQNPDKVQSLNVDAIIRGGLTRFTDQLGKLWCSLADYYI 267 Query: 749 KLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSM 808 + G A + A+ + D Y +E I + + +E Sbjct: 268 RSGHFEKARDVYEEAIRT--VMTVRDFTQVFD-SYAQFEESMIAAKMETASELGREEEDD 324 Query: 809 TD 810 D Sbjct: 325 VD 326 Score = 42.9 bits (99), Expect = 7e-04, Method: Composition-based stats. Identities = 33/220 (15%), Positives = 65/220 (29%), Gaps = 41/220 (18%) Query: 559 LTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAI----------QVDPNYAY------ 602 LT + WC+ + + + A ++ AI QV +YA Sbjct: 248 LTRFTDQLGKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMI 307 Query: 603 -----AYTLLGHEFVLTEELDKALACFRNAIRVNP----------RHYNAWYGLGMIYYK 647 + LG E +L+ LA F I P ++ + Sbjct: 308 AAKMETASELGREEEDDVDLELRLARFEQLISRRPLLLNSVLLRQNPHHVHEWHKRVALH 367 Query: 648 QEKFSLAEMHFQKALD-INPQSS-----VLLCHIGVVQHALKKSEKALDTLNKAIVID-- 699 Q + + +A+ ++P + L + + A L KA ++ Sbjct: 368 QGRPREIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFK 427 Query: 700 --PKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 + +E Y AL+ L + + + + Sbjct: 428 QVDDLASVWCQCGELELRHENYDEALRLLRKATALPARRA 467 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 33/296 (11%), Positives = 92/296 (31%), Gaps = 32/296 (10%) Query: 499 GWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIY-STTLWHLQKDVALSVLSK 557 G + C + Y + +A ++ E R + +++ S + A + Sbjct: 256 GKLWCSLADYYIRSGHFEKARDVYEEAIRTVMTVRDFTQVFDSYAQFEESMIAAKMETAS 315 Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEEL 617 +L +++ + L + ++ +P++ + + + Sbjct: 316 ELGREEEDDVDLELRLARFEQLISR--RPLLLNSVLLRQNPHHVHEW--HKRVALHQGRP 371 Query: 618 DKALACFRNAIR-VNP-----RHYNAWYGLGMIYYKQEKFSLAEMHFQKALDIN----PQ 667 + + + A++ V+P + + W Y + A + +KA +N Sbjct: 372 REIINTYTEAVQTVDPFKATGKPHTLWVAFAKFYEDNGQLDDARVILEKATKVNFKQVDD 431 Query: 668 SSVLLCHIGVVQHALKKSEKALDTLNKAIVI--------DPKNPLCK--FHRASVLFANE 717 + + C G ++ + ++AL L KA + D P+ + V Sbjct: 432 LASVWCQCGELELRHENYDEALRLLRKATALPARRAEYFDGSEPVQNRVYKSLKVWSMLA 491 Query: 718 KYKSALQELEELKQIVPK-------ESLVYFLIGKVYKKLGQTHLALMNFSWAMDL 766 + +L + K + + + ++ + + + L Sbjct: 492 DLEESLGTFQSTKAVYDRILDLRIATPQIVINYAMFLEEHKYFEESFKAYERGISL 547 >4HOU-A nrPDB Length = 273 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 25/173 (14%), Positives = 62/173 (35%), Gaps = 13/173 (7%) Query: 567 PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRN 626 EA ++ ++ ++ ++D +A G + ++A ACF Sbjct: 106 AEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKCGG-----KNYERAKACFEK 160 Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHF--------QKALDINPQSSVLLCHIGVV 678 + V+P + + G + Y+ + F LA + ++A+ +NP + + + + Sbjct: 161 VLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALK 220 Query: 679 QHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ 731 + + + +A+ + A AL+ L++ Q Sbjct: 221 LQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKALQ 273 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 30/182 (16%), Positives = 65/182 (35%), Gaps = 26/182 (14%) Query: 539 YSTTLWHLQKDVA-------LSVLSKDLTDMDKNSPE--------AWCAAGNCFSLQREH 583 ++ +H+ + + + K L++ + E W + + Sbjct: 95 FAWMYYHMGRLAEAQTYLDKVENICKKLSNPFRYRMECPEIDCEEGWALLKC---GGKNY 151 Query: 584 DIAIKFFQRAIQVDPNY--------AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHY 635 + A F++ ++VDP AY L G + +L R A+R+NP + Sbjct: 152 ERAKACFEKVLEVDPENPESSAGYAISAYRLDGFKLATKNHKPFSLLPLRQAVRLNPDNG 211 Query: 636 NAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKA 695 L + + + + E + ++AL + + + +KAL+ L KA Sbjct: 212 YIKVLLALKLQDEGQEAEGEKYIEEALANMSSQTYVFRYAAKFYRRKGSVDKALELLKKA 271 Query: 696 IV 697 + Sbjct: 272 LQ 273 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 30/185 (16%), Positives = 60/185 (32%), Gaps = 22/185 (11%) Query: 642 GMIYYKQEKFSLAEMHFQKAL--DINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVID 699 G + AE Q+ N +S V + + + + + +A L+K I Sbjct: 60 GQNEEALKSLKEAENLMQEEHDNQANVRSLVTWGNFAWMYYHMGRLAEAQTYLDKVENIC 119 Query: 700 PK------------NPLCKFHRASVLFANEKYKSALQELEELKQIVPKES--------LV 739 K C+ A + + Y+ A E++ ++ P+ Sbjct: 120 KKLSNPFRYRMECPEIDCEEGWALLKCGGKNYERAKACFEKVLEVDPENPESSAGYAISA 179 Query: 740 YFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMG 799 Y L G +L+ A+ L+P ++ A+ + + E E+ + Sbjct: 180 YRLDGFKLATKNHKPFSLLPLRQAVRLNPDNGYIKVLLALKLQDEGQEAEGEKYIEEALA 239 Query: 800 TDESQ 804 SQ Sbjct: 240 NMSSQ 244 >3J98-H nrPDB Length = 297 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 47/251 (18%), Positives = 85/251 (33%), Gaps = 38/251 (15%) Query: 539 YSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDP 598 +S K + +M K + W AAGN F + + ++ A Sbjct: 30 FSGLFGGSSKIEEACEIYARAANMFK-MAKNWSAAGNAFCQAAQLHLQLQSKHDAATC-- 86 Query: 599 NYAYAYTLLGHEFVLTEELDKALACFRNAIRV---NPRHYNA---WYGLGMIYY-KQEKF 651 + A G+ F + +A+ C AI + R A + IY + Sbjct: 87 -FVDA----GNAFKKA-DPQEAINCLMRAIEIYTDMGRFTIAAKHHISIAEIYETELVDV 140 Query: 652 SLAEMHF------QKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC 705 A H+ K + N ++ L + L++ +KA+D + +PL Sbjct: 141 EKAIAHYEQSADYYKGEESNSSANKCLLKVAGYAAQLEQYQKAIDIYEQVGTSAMDSPLL 200 Query: 706 KFH---------RASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHL- 755 K+ K A+Q+ EEL P S K+ KKL + H Sbjct: 201 KYSAKDYFFKAALCHFCIDMLNAKLAVQKYEEL---FPAFSDSREC--KLMKKLLEAHEE 255 Query: 756 -ALMNFSWAMD 765 + +++ ++ Sbjct: 256 QNVDSYTESVK 266 >5NLG-A nrPDB Length = 314 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 64/215 (29%), Gaps = 15/215 (6%) Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV--------DPNYAYAYTLLGH 609 L + NS W E + A + +RA++ N A L + Sbjct: 59 RLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLEN 118 Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQ-KALDINPQS 668 F E L++ F A + Y L IY EKF A F+ A + Sbjct: 119 TFGTEETLEEV---FSRACQYMDS-YTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEK 174 Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDP--KNPLCKFHRASVLFANEKYKSALQEL 726 + G + + ++A L A+ P + A + FA + Sbjct: 175 VSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLF 234 Query: 727 EELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFS 761 E L PK ++ + K F Sbjct: 235 EGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFE 269 Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 41/116 (35%), Gaps = 4/116 (3%) Query: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIV---IDPKNPLCK 706 + + F++ L NP SSV+ + Q L + EKA + +A+ + Sbjct: 49 RAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLN 108 Query: 707 FHRASVLFANE-KYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFS 761 A + N + L+E+ ++ + +Y+ + A F Sbjct: 109 IWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFK 164 >5C9S-B nrPDB Length = 572 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 40/215 (18%), Positives = 64/215 (29%), Gaps = 15/215 (6%) Query: 558 DLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV--------DPNYAYAYTLLGH 609 L + NS W E + A + +RA++ N A L + Sbjct: 309 RLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLNIWIAMLNLEN 368 Query: 610 EFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQ-KALDINPQS 668 F E L++ F A + Y L IY EKF A F+ A + Sbjct: 369 TFGTEETLEEV---FSRACQYMDS-YTIHTKLLGIYEISEKFDKAAELFKATAKKFGGEK 424 Query: 669 SVLLCHIGVVQHALKKSEKALDTLNKAIVIDP--KNPLCKFHRASVLFANEKYKSALQEL 726 + G + + ++A L A+ P + A + FA + Sbjct: 425 VSIWVSWGDFLISHNEEQEARTILGNALKALPKRNHIEVVRKFAQLEFAKGDPERGRSLF 484 Query: 727 EELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFS 761 E L PK ++ + K F Sbjct: 485 EGLVADAPKRIDLWNVYVDQEVKAKDKKKVEDLFE 519 Score = 30.9 bits (68), Expect = 2.0, Method: Composition-based stats. Identities = 20/116 (17%), Positives = 41/116 (35%), Gaps = 4/116 (3%) Query: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIV---IDPKNPLCK 706 + + F++ L NP SSV+ + Q L + EKA + +A+ + Sbjct: 299 RAPESVADFERLLIGNPNSSVVWMNYMAFQLQLSEIEKARELAERALKTINFREEAEKLN 358 Query: 707 FHRASVLFANE-KYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFS 761 A + N + L+E+ ++ + +Y+ + A F Sbjct: 359 IWIAMLNLENTFGTEETLEEVFSRACQYMDSYTIHTKLLGIYEISEKFDKAAELFK 414 >5OMP-A nrPDB Length = 462 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 59/153 (38%), Gaps = 19/153 (12%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 G + ++ A+ + + + ++ + E+ L+E+ KA F A Sbjct: 280 GTVYFKGGKYMQAVIQYGKIV--------SWLEM--EYGLSEKESKASESFLLA------ 323 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 A+ L M Y K +++ A KAL ++ + L G Q + + E A Sbjct: 324 ---AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 380 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQEL 726 K + ++P+N + + +++ + + Sbjct: 381 KVLEVNPQNKAARLQISMCQKKAKEHNERDRRI 413 Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 34/194 (17%), Positives = 68/194 (35%), Gaps = 32/194 (16%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 ++ + G YF+ +YMQA + ++ V +E+ K +L+ Sbjct: 275 IVKEKGTVYFKGGKYMQAVIQYGKI-------VSWLEMEYGLSEKESKASESFLLA---- 323 Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 A+ C+ RE+ A++ +A+ +D G +L E + A Sbjct: 324 --------AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 375 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQH 680 F + VNP++ A + M +KA + N + + ++ Sbjct: 376 KGDFEKVLEVNPQNKAARLQISMCQ-------------KKAKEHNERDRRIYANMFKKFA 422 Query: 681 ALKKSEKALDTLNK 694 E+A + K Sbjct: 423 EQDAKEEANKAMGK 436 Score = 36.3 bits (82), Expect = 0.059, Method: Composition-based stats. Identities = 34/215 (15%), Positives = 67/215 (31%), Gaps = 32/215 (14%) Query: 626 NAIRVNPRHYNAWYGLGMIYY--KQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 A+ R LG Y + K I P + ++ + LK Sbjct: 209 KALEKMQREEQCILYLGPRYGFGEAGKPK---------FGIEPNAELIY------EVTLK 253 Query: 684 KSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ-------IVPKE 736 EKA ++ + + +V F KY A+ + ++ + KE Sbjct: 254 SFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYMQAVIQYGKIVSWLEMEYGLSEKE 313 Query: 737 S--------LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDE 788 S + + Y KL + A+ A+ LD + + + + E Sbjct: 314 SKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFE 373 Query: 789 EPITQEEQIMGTDESQESSMTDADDTQLHAAESDE 823 E+++ + +++ Q A E +E Sbjct: 374 SAKGDFEKVLEVNPQNKAARLQISMCQKKAKEHNE 408 >4GYO-A nrPDB Length = 373 Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 33/253 (13%), Positives = 80/253 (31%), Gaps = 44/253 (17%) Query: 490 HLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIE---NYRVEGMEIYS-TTLWH 545 H+ + L + + + ++ +++ NY + ++IY+ L+ Sbjct: 117 LAIDHYKHAEEKLEYVEDEIEKAEFLFKVAEVYYHIKQTYFSMNYASQALDIYTKYELYG 176 Query: 546 LQKDVALSVLSKDLTDMDKNS----------------------PEAWCAAGNCFSLQREH 583 ++ +++ +LTD+ + A+ G+C ++ Sbjct: 177 RRRVQCEFIIAGNLTDVYHHEKALTHLCSALEHARQLEEAYMIAAAYYNVGHCKYSLGDY 236 Query: 584 DIAIKFFQRAIQV--DPNY---AYAYTLLGHEFVLTEELDKALACFRNAIR--------- 629 A +F+ A + + N+ A L H + + DKA+ + I+ Sbjct: 237 KEAEGYFKTAAAIFEEHNFQQAVQAVFSLTHIYCKEGKYDKAVEAYDRGIKSAAEWEDDM 296 Query: 630 -VNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 + LG + ++ + + LL + L+ E A Sbjct: 297 YLTKFRLIHELYLGS--GDLNVLTECFDLL-ESRQLLADAEDLLHDTAERFNQLEHYESA 353 Query: 689 LDTLNKAIVIDPK 701 + + I K Sbjct: 354 AFFYRRLMNIKKK 366 >1KT1-A nrPDB Length = 457 Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 57/148 (38%), Gaps = 22/148 (14%) Query: 574 GNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPR 633 G + ++ A+ + + + ++ + E+ L+E+ KA F A Sbjct: 275 GTVYFKGGKYVQAVIQYGKIV--------SWLEM--EYGLSEKESKASESFLLA------ 318 Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 A+ L M Y K +++ A KAL ++ + L G Q + + E A Sbjct: 319 ---AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESAKGDFE 375 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKS 721 K + ++P+N R + +K K Sbjct: 376 KVLEVNPQNKAA---RLQIFMCQKKAKE 400 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 33/194 (17%), Positives = 68/194 (35%), Gaps = 32/194 (16%) Query: 501 VLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLT 560 ++ + G YF+ +Y+QA + ++ V +E+ K +L+ Sbjct: 270 IVKEKGTVYFKGGKYVQAVIQYGKI-------VSWLEMEYGLSEKESKASESFLLA---- 318 Query: 561 DMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKA 620 A+ C+ RE+ A++ +A+ +D G +L E + A Sbjct: 319 --------AFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNEFESA 370 Query: 621 LACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQH 680 F + VNP++ A + M +KA + N + ++ Sbjct: 371 KGDFEKVLEVNPQNKAARLQIFMCQ-------------KKAKEHNERDRRTYANMFKKFA 417 Query: 681 ALKKSEKALDTLNK 694 E+A ++K Sbjct: 418 EQDAKEEANKAMSK 431 Score = 33.2 bits (74), Expect = 0.47, Method: Composition-based stats. Identities = 26/157 (16%), Positives = 53/157 (33%), Gaps = 15/157 (9%) Query: 682 LKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQ-------IVP 734 LK EKA ++ + + +V F KY A+ + ++ + Sbjct: 247 LKSFEKAKESWEMDTKEKLEQAAIVKEKGTVYFKGGKYVQAVIQYGKIVSWLEMEYGLSE 306 Query: 735 KES--------LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPD 786 KES + + Y KL + A+ A+ LD + + + + Sbjct: 307 KESKASESFLLAAFLNLAMCYLKLREYTKAVECCDKALGLDSANEKGLYRRGEAQLLMNE 366 Query: 787 DEEPITQEEQIMGTDESQESSMTDADDTQLHAAESDE 823 E E+++ + +++ Q A E +E Sbjct: 367 FESAKGDFEKVLEVNPQNKAARLQIFMCQKKAKEHNE 403 >5MGX-E nrPDB Length = 290 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 19/127 (14%), Positives = 37/127 (29%), Gaps = 5/127 (3%) Query: 589 FFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQ 648 +QRA ++ A K F ++ L K Sbjct: 141 HYQRA-----DFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKL 195 Query: 649 EKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFH 708 + + A L+ P + L G V + +A+ L A+ ++P N Sbjct: 196 DHYRAALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAE 255 Query: 709 RASVLFA 715 + ++ Sbjct: 256 LSKLVKK 262 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 20/109 (18%), Positives = 38/109 (34%) Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 A + + A+ S K T + + C + A+ + Y+ Sbjct: 140 AHYQRADFVLAANSYDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYR 199 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 +AL+ + + P F GKV + G+ A+ A+ L+P Sbjct: 200 AALRSCSLVLEHQPDNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPS 248 Score = 35.9 bits (81), Expect = 0.063, Method: Composition-based stats. Identities = 23/128 (17%), Positives = 46/128 (35%), Gaps = 10/128 (7%) Query: 583 HDIAIKFFQRAIQVDPNY---AYAYTLLGHEFVLTEELDKALACFRNAIRV-------NP 632 +D+AIK + +VD + A L L +R A+R P Sbjct: 154 YDLAIKAITSSAKVDMTFEEEAQLLQLKVKCLNNLAASQLKLDHYRAALRSCSLVLEHQP 213 Query: 633 RHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTL 692 + A + G + +Q ++S A + AL + P + + + + L Sbjct: 214 DNIKALFRKGKVLAQQGEYSEAIPILRAALKLEPSNKTIHAELSKLVKKHAAQRSTETAL 273 Query: 693 NKAIVIDP 700 + ++ +P Sbjct: 274 YRKMLGNP 281 >4I2W-A nrPDB Length = 961 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 17/101 (16%), Positives = 37/101 (36%), Gaps = 5/101 (4%) Query: 654 AEMHFQKALDINPQS-----SVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFH 708 A+ + +AL + VL + + + E A KA+ D + F Sbjct: 27 ADELYTEALQLTTDEDKALRPVLYRNRAMARLKRDDFEGAQSDCTKALEFDGADVKALFR 86 Query: 709 RASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKK 749 R+ A Q+ +E ++ P + + ++ ++ K Sbjct: 87 RSLAREQLGNVGPAFQDAKEALRLSPNDKGIVEVLQRLVKA 127 >5LJ5-S nrPDB Length = 687 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 25/233 (10%), Positives = 73/233 (31%), Gaps = 26/233 (11%) Query: 599 NYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHF 658 ++ + + + +++ KA AI + P+ + G + K ++F + Sbjct: 402 TFSKIWLMYAKFLIRHDDVPKARKILGKAIGLCPK-AKTFKGYIELEVKLKEFDRVRKIY 460 Query: 659 QKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKN------PLCKFHRASV 712 +K ++ P + G ++ L ++ A+ + + + Sbjct: 461 EKFIEFQPSDLQIWSQYGELEENLGDWDRVRGIYTIALDENSDFLTKEAKIVLLQKYITF 520 Query: 713 LFANEKYKSALQELEELKQI----------VPKESLVYFLIGKVYKKLGQTHLALMN-FS 761 +++++ A + ++ ++ + Sbjct: 521 ETESQEFEKARKLYRRYLELNQYSPQSWIEFAMYQTSTPTEQQLLDLAKLQSENVDEDIE 580 Query: 762 WAMDLDPKGANNQI--------KEAIDKRYLPDDEEPITQEEQIMGTDESQES 806 + + + K ++ KE DK+ E + E+ GT+ QE+ Sbjct: 581 FEITDENKLEARKVFEEAIVFFKEKDDKQGRLSILEALKDYEETYGTELDQET 633 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 34/274 (12%), Positives = 78/274 (28%), Gaps = 50/274 (18%) Query: 545 HLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAY 604 ++ L ++ DM + W Q + A F+RA+ VD ++ + Sbjct: 48 RRKRTEYEGYLKRNRLDMGQ-----WIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLW 102 Query: 605 TLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 + + ++ A AI PR WY ++ + + K + Sbjct: 103 IRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSL 162 Query: 665 NPQSS-------------------VLLCHIGVVQHALKKSEKAL-------------DTL 692 P + + + ++ K + Sbjct: 163 EPGVNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHGNTEFTRSVY 222 Query: 693 NKAIVI-----------DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF 741 + AI D + A A ++Y+ + + + P L+ Sbjct: 223 SLAIDTVANLQNLQIWSDMEVAKLVNSFAHWEAAQQEYERSSALYQIAIEKWPSNQLLKA 282 Query: 742 LIGKVYKKLGQTH--LALMNFSWAMDLDPKGANN 773 + K+ G + +++ M+ + +NN Sbjct: 283 GLLDFEKQFGDINSIEETISYKRKMEYETILSNN 316 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 24/213 (11%), Positives = 64/213 (30%), Gaps = 14/213 (6%) Query: 578 SLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNA 637 L+ ++ ++ + + + ++ +A + F A+ V+ Sbjct: 42 ELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPL 101 Query: 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIV 697 W K + + A +A+ P+ L +V+ +L E K Sbjct: 102 WIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCS 161 Query: 698 IDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK--KLGQTHL 755 ++P + + ++ + +++I K + + + K + H Sbjct: 162 LEPG--------VNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHG 213 Query: 756 ALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDE 788 L A + + + + D E Sbjct: 214 NTEFTRSVYSL----AIDTVANLQNLQIWSDME 242 >2IFU-A nrPDB Length = 307 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 29/197 (14%), Positives = 60/197 (30%), Gaps = 28/197 (14%) Query: 581 REHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYG 640 ++ A + +A + + E KA F+NA ++ +A+ Sbjct: 5 QKISEAHEHIAKAEKYLKTSFMKW--KPDYDSAASEYAKAAVAFKNAKQLEQAK-DAYLQ 61 Query: 641 LGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI-- 698 + A F++A G++ L++ +A+ + KA V+ Sbjct: 62 EAEAHANNRSLFHAAKAFEQA--------------GMMLKDLQRMPEAVQYIEKASVMYV 107 Query: 699 ---DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYF---LIGKV---YKK 749 P RA L A+ ++ + E + LIGK + Sbjct: 108 ENGTPDTAAMALDRAGKLMEPLDLSKAVHLYQQAAAVFENEERLRQAAELIGKASRLLVR 167 Query: 750 LGQTHLALMNFSWAMDL 766 + A + + Sbjct: 168 QQKFDEAAASLQKEKSM 184 >5GMK-d nrPDB Length = 687 Score = 38.6 bits (88), Expect = 0.013, Method: Composition-based stats. Identities = 20/122 (16%), Positives = 40/122 (32%), Gaps = 5/122 (4%) Query: 545 HLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAY 604 ++ L ++ DM + W Q + A F+RA+ VD ++ + Sbjct: 48 RRKRTEYEGYLKRNRLDMGQ-----WIRYAQFEIEQHDMRRARSIFERALLVDSSFIPLW 102 Query: 605 TLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDI 664 + + ++ A AI PR WY ++ + + K + Sbjct: 103 IRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCSL 162 Query: 665 NP 666 P Sbjct: 163 EP 164 Score = 35.2 bits (79), Expect = 0.13, Method: Composition-based stats. Identities = 24/213 (11%), Positives = 64/213 (30%), Gaps = 14/213 (6%) Query: 578 SLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNA 637 L+ ++ ++ + + + ++ +A + F A+ V+ Sbjct: 42 ELREYQRRKRTEYEGYLKRNRLDMGQWIRYAQFEIEQHDMRRARSIFERALLVDSSFIPL 101 Query: 638 WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIV 697 W K + + A +A+ P+ L +V+ +L E K Sbjct: 102 WIRYIDAELKVKCINHARNLMNRAISTLPRVDKLWYKYLIVEESLNNVEIVRSLYTKWCS 161 Query: 698 IDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYK--KLGQTHL 755 ++P + + ++ + +++I K + + + K + H Sbjct: 162 LEPG--------VNAWNSFVDFEIRQKNWNGVREIYSKYVMAHPQMQTWLKWVRFENRHG 213 Query: 756 ALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDE 788 L A + + + + D E Sbjct: 214 NTEFTRSVYSL----AIDTVANLQNLQIWSDME 242 >3QDN-A nrPDB Length = 287 Score = 38.2 bits (87), Expect = 0.015, Method: Composition-based stats. Identities = 27/160 (16%), Positives = 59/160 (36%), Gaps = 2/160 (1%) Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 ++A+ + +V PR M ++ + A + A ++ Q+S + + Sbjct: 102 EEAIRALLD--KVLPREEELKAQQAMQLMQEGNYIDALPLLKDAWQLSSQNSEIGLLLAE 159 Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 Q AL +SE+A L + D L +Q+L++ P+++ Sbjct: 160 AQIALNRSEEAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVADNPQDA 219 Query: 738 LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKE 777 + + ++G+ AL + D A Q ++ Sbjct: 220 ALATQLALQLHQVGRNEEALELLFSHLRKDLTAAEGQTRK 259 Score = 33.6 bits (75), Expect = 0.39, Method: Composition-based stats. Identities = 29/139 (20%), Positives = 52/139 (37%), Gaps = 5/139 (3%) Query: 686 EKALDTL-NKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIG 744 E+A+ L +K + P+ K +A L Y AL L++ Q+ + S + L+ Sbjct: 102 EEAIRALLDKVL---PREEELKAQQAMQLMQEGNYIDALPLLKDAWQLSSQNSEIGLLLA 158 Query: 745 KVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQ 804 + L ++ A D + I+ D P Q+ Q D Q Sbjct: 159 EAQIALNRSEEAEAVLKTIPLQDQDTRYQGLVAQIELLKQAAD-TPEIQQLQQQVADNPQ 217 Query: 805 ESSMTDADDTQLHAAESDE 823 ++++ QLH +E Sbjct: 218 DAALATQLALQLHQVGRNE 236 >5BT1-A nrPDB Length = 393 Score = 37.9 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 25/146 (17%), Positives = 45/146 (30%), Gaps = 16/146 (10%) Query: 601 AYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQK 660 Y L+G E +A+ + A+ + L EK AE Sbjct: 236 GDVYILMGDIEREAEMFSRAIHHYLKALGY-------YKTLKPAEQVTEKVIQAEFLVCD 288 Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLC-KFHRASVLFANEKY 719 AL + LK+ + A L K + PK+ + A + ++ Sbjct: 289 ALR--------WVDQVPAKDKLKRFKHAKALLEKHMTTRPKDSELQQARLAQIQDDIDEV 340 Query: 720 KSALQELEELKQIVPKESLVYFLIGK 745 + Q + P S+ + + K Sbjct: 341 QENQQHGSKRPLSQPTTSIGFPALEK 366 >5JHE-A nrPDB Length = 397 Score = 37.9 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 27/196 (13%), Positives = 61/196 (31%), Gaps = 18/196 (9%) Query: 543 LWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQV---DPN 599 +W V L S D D + A + + + + Sbjct: 200 VWEKTMGVPLYNASNDQIGGDVYEEYPDDDTHFGDDDFGKALEAANIIKESGTLLFKKKD 259 Query: 600 YAYAY------TLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSL 653 Y+ A+ +E++ ++DK I+ + L ++ + E++ Sbjct: 260 YSNAFFKYRKSLNYINEYMPEPDVDK-----ERNIQFINLKMKIYLNLSLVLFNLERYDD 314 Query: 654 AEMHFQKALDI----NPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHR 709 A M+ L++ N + G K+ ++AL +P + + + Sbjct: 315 AIMYATYLLEMDNVPNRDQAKAYYRRGNSYLKKKRLDEALQDYIFCKEKNPDDEVIEQRI 374 Query: 710 ASVLFANEKYKSALQE 725 V E+ K ++ Sbjct: 375 EYVNRLIEENKEKTRK 390 >5OQL-E nrPDB Length = 414 Score = 37.9 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 27/81 (33%) Query: 564 KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC 623 S E W A + + + RA+++ P A +TL G ++ +A A Sbjct: 104 PGSIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAH 163 Query: 624 FRNAIRVNPRHYNAWYGLGMI 644 F R R W Sbjct: 164 FLRGCRFCTREPTLWLEYARC 184 Score = 32.8 bits (73), Expect = 0.60, Method: Composition-based stats. Identities = 20/121 (16%), Positives = 36/121 (29%), Gaps = 2/121 (1%) Query: 571 CAAGNCFSLQREHDIAIKF--FQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAI 628 CA N S+ A F F+RA+ P + + + A+ Sbjct: 75 CARLNIRSVTSHASQARTFGIFERAVLKHPGSIELWLAYLEFAAQVKATKRWRRIMTRAL 134 Query: 629 RVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 R++P + + W G + A HF + + L + +A Sbjct: 135 RLHPMNASLWTLAGRRAAQNGDMQRARAHFLRGCRFCTREPTLWLEYARCEMDWLARMEA 194 Query: 689 L 689 Sbjct: 195 K 195 >5IC8-A nrPDB Length = 334 Score = 37.9 bits (86), Expect = 0.020, Method: Composition-based stats. Identities = 17/81 (20%), Positives = 27/81 (33%) Query: 564 KNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC 623 S E W A + + + RA+++ P A +TL G ++ +A A Sbjct: 24 PGSIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNGDMQRARAH 83 Query: 624 FRNAIRVNPRHYNAWYGLGMI 644 F R R W Sbjct: 84 FLRGCRFCTREPTLWLEYARC 104 Score = 31.7 bits (70), Expect = 1.5, Method: Composition-based stats. Identities = 14/100 (14%), Positives = 29/100 (29%) Query: 590 FQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 649 F+RA+ P + + + A+R++P + + W G + Sbjct: 16 FERAVLKHPGSIELWLAYLEFAAQVKATKRWRRIMTRALRLHPMNASLWTLAGRRAAQNG 75 Query: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKAL 689 A HF + + L + +A Sbjct: 76 DMQRARAHFLRGCRFCTREPTLWLEYARCEMDWLARMEAK 115 >6G70-A nrPDB Length = 670 Score = 37.1 bits (84), Expect = 0.031, Method: Composition-based stats. Identities = 14/93 (15%), Positives = 28/93 (30%) Query: 590 FQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQE 649 F + ++++P + L L A F P Y W + + + Sbjct: 87 FWKTVEMNPQDFTGWVYLLQYVEQENHLMAARKAFDKFFVHYPYCYGYWKKYADLEKRHD 146 Query: 650 KFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL 682 ++ +++ L P S L H Sbjct: 147 NIKQSDEVYRRGLQAIPLSVDLWIHYINFLKET 179 >3LVG-A nrPDB Length = 624 Score = 37.1 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 20/162 (12%), Positives = 38/162 (23%), Gaps = 32/162 (19%) Query: 626 NAIRVNPRHYNA--WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 A R W L ++ A + KA + + Sbjct: 43 RAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKA-----DDPSSYMEVVQAANTSG 97 Query: 684 KSEKALDTLNKA--------IVIDPKNPLCKFHRASVLFANEK--------------YKS 721 E+ + L A + + L K +R + L Y Sbjct: 98 NWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDE 157 Query: 722 ALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763 + + +L + + LG+ A+ A Sbjct: 158 KMYDAAKLLY---NNVSNFGRLASTLVHLGEYQAAVDGARKA 196 >1B89-A nrPDB Length = 449 Score = 37.1 bits (84), Expect = 0.034, Method: Composition-based stats. Identities = 20/162 (12%), Positives = 38/162 (23%), Gaps = 32/162 (19%) Query: 626 NAIRVNPRHYNA--WYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALK 683 A R W L ++ A + KA + + Sbjct: 21 RAYEFAERCNEPAVWSQLAKAQLQKGMVKEAIDSYIKA-----DDPSSYMEVVQAANTSG 75 Query: 684 KSEKALDTLNKA--------IVIDPKNPLCKFHRASVLFANEK--------------YKS 721 E+ + L A + + L K +R + L Y Sbjct: 76 NWEELVKYLQMARKKARESYVETELIFALAKTNRLAELEEFINGPNNAHIQQVGDRCYDE 135 Query: 722 ALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWA 763 + + +L + + LG+ A+ A Sbjct: 136 KMYDAAKLLY---NNVSNFGRLASTLVHLGEYQAAVDGARKA 174 >5ZYP-A nrPDB Length = 390 Score = 36.7 bits (83), Expect = 0.043, Method: Composition-based stats. Identities = 25/174 (14%), Positives = 59/174 (33%), Gaps = 19/174 (10%) Query: 557 KDLTDMDKNSPEAWCAAGNCFSLQREHDIAIK---FFQRAI---------QVDPNYAYAY 604 KD D A + + +D A++ F ++I Q PN + Sbjct: 128 KDAIGFDPTWIGNMLATVELYYQRGHYDKALETSDLFVKSIHAEDHRSGRQSKPNCLFLL 187 Query: 605 TLLGHEFVLTEELDKALACFRNAIRVNPR-HYNAWYGLGMIYYKQEKFSLAEMHFQKALD 663 + + +L F+ + +NP + G+G+ +++ + +A +Q+AL Sbjct: 188 LRAKLLYQK-KNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDSKMAIKSWQRALQ 246 Query: 664 INPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANE 717 +NP++ + L + ++ ++ N+ Sbjct: 247 LNPKN-----TSASILVLLGEFRESFTNSTNDKTFKEAFTKALSDLNNIFSENQ 295 Score = 34.4 bits (77), Expect = 0.19, Method: Composition-based stats. Identities = 49/266 (18%), Positives = 92/266 (34%), Gaps = 42/266 (15%) Query: 581 REHDI--AIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALAC------------FRN 626 +EH++ A + AI DP + + DKAL R+ Sbjct: 116 KEHELTQAELNLKDAIGFDPTWIGNMLATVELYYQRGHYDKALETSDLFVKSIHAEDHRS 175 Query: 627 AIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQ-SSVLLCHIGVVQHALKKS 685 + P ++Y K + + + FQ+ L INP IG+ LK S Sbjct: 176 GRQSKPNCLFLLLRAKLLYQK-KNYMASLKIFQELLVINPVLQPDPRIGIGLCFWQLKDS 234 Query: 686 EKALDTLNKAIVIDPKNPLCKF------------HRASVLFANEKYKSALQELEELKQIV 733 + A+ + +A+ ++PKN + + E + AL +L + Sbjct: 235 KMAIKSWQRALQLNPKNTSASILVLLGEFRESFTNSTNDKTFKEAFTKALSDLNNIFSEN 294 Query: 734 PKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANN-QIKEAIDKRYLP-DDEEPI 791 ++ L+ Y F +L + N + I+ Y+ + I Sbjct: 295 QHNPVLLTLLQTYY-----------YFKGDENLYFQSETNADSSQLINSLYIKTNVTNLI 343 Query: 792 TQEEQI-MGTDESQESSMTDADDTQL 816 Q+E + M D + + + D++L Sbjct: 344 QQDEDLGMPVDLMKFPGLLNKLDSKL 369 >4D18-C nrPDB Length = 427 Score = 36.3 bits (82), Expect = 0.048, Method: Composition-based stats. Identities = 37/261 (14%), Positives = 86/261 (32%), Gaps = 36/261 (13%) Query: 551 ALSVLSKDLTDMDKNSPEAWCAAGNCFSL--------QREHDIAIKFFQRAIQVDPNYAY 602 AL L D+ D+ K + C+ + + A+ F+++AI P A Sbjct: 162 ALPYLDVDMMDICKENGAYDAKHFLCYYYYGGMIYTGLKNFERALYFYEQAIT-TPAMAV 220 Query: 603 AYTLLGH-------EFVLTEELDKALACFRNAI--RVNPRHYNAWYGLGMIYYKQEKFSL 653 ++ +L +L ++ + L + + I R NA++ L +Y S Sbjct: 221 SHIMLESYKKYILVSLILLGKVQQ-LPKYTSQIVGRFIKPLSNAYHELAQVY-STNNPSE 278 Query: 654 AEMHFQKALDINPQSSVL-LCHIGVVQHALKKSEKALDTLNKAIVID------------- 699 K + + + + L + K ++ T + D Sbjct: 279 LRNLVNKHSETFTRDNNMGLVKQCLSSLYKKNIQRLTKTFLTLSLQDMASRVQLSGPQEA 338 Query: 700 PKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMN 759 K L + FA+ K + + + ++++ + ++ K + + L Sbjct: 339 EKYVLHMIEDGEI-FASINQKDGMVSFHDNPEKYNNPAMLHNIDQEMLKCI-ELDERLKA 396 Query: 760 FSWAMDLDPKGANNQIKEAID 780 + ++P+ + D Sbjct: 397 MDQEITVNPQFVQKSMGSQED 417 >4CGU-A nrPDB Length = 112 Score = 36.3 bits (82), Expect = 0.056, Method: Composition-based stats. Identities = 13/73 (17%), Positives = 26/73 (35%) Query: 710 ASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPK 769 + LF Y+ A+ ++L P+ + Y KLG+ A+ + Sbjct: 12 GNSLFKQGLYREAVHCYDQLITAQPQNPVGYSNKAMALIKLGEYTQAIQMCQQGLRYTST 71 Query: 770 GANNQIKEAIDKR 782 + I+ + R Sbjct: 72 AEHVAIRSKLQYR 84 >6MFV-A nrPDB Length = 653 Score = 35.5 bits (80), Expect = 0.099, Method: Composition-based stats. Identities = 26/136 (19%), Positives = 51/136 (37%), Gaps = 10/136 (7%) Query: 656 MHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFH--RASVL 713 +Q+ L + I +++ EKA+ L +A + C+ + A Sbjct: 353 RMYQRLLMEVEDNPYAKIEIAIIEVQRGLFEKAIKLLKEAEPYVDEFFKCEIYSWLADAY 412 Query: 714 FANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANN 773 E + A + L++ K+IV K + +Y +K + N A+ + Sbjct: 413 MELENLEKAERYLKKTKEIVEKINDMYAWFSYYAEKT-KYEYYKENSREAL-------KS 464 Query: 774 QIKEAIDKRYLPDDEE 789 +KE R + D E+ Sbjct: 465 ALKELEIIRKIGDPEK 480 Score = 32.8 bits (73), Expect = 0.66, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 49/145 (33%), Gaps = 20/145 (13%) Query: 569 AWCAAGNCFSLQREHDIAIKFFQRAIQV--DPNYAYAYTLLGHEFVL----TEELDKALA 622 +W A + + + A ++ ++ ++ N YA+ E E +AL Sbjct: 406 SWLA--DAYMELENLEKAERYLKKTKEIVEKINDMYAWFSYYAEKTKYEYYKENSREALK 463 Query: 623 CFRNAIRVNPRHYNAWYG------LGMIYYKQEKFSLAEMHFQKALDINPQSSV------ 670 + + + + +G IY + ++Q+AL + + Sbjct: 464 SALKELEIIRKIGDPEKEGLVLLHVGDIYLHMGNYEKGISYYQEALKMAKAYGIKFLEHI 523 Query: 671 LLCHIGVVQHALKKSEKALDTLNKA 695 + + LK EKA + KA Sbjct: 524 SYMELAKGYYQLKLYEKASEYSEKA 548 >3JB9-R nrPDB Length = 674 Score = 34.4 bits (77), Expect = 0.20, Method: Composition-based stats. Identities = 23/127 (18%), Positives = 42/127 (33%), Gaps = 1/127 (0%) Query: 611 FVLTEELDK-ALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSS 669 +E F +AIR N W G Q++F+ A F++ALD++ Sbjct: 45 LEELQEFQGRKRKEFEDAIRRNRLAMGHWMRYGQWELDQKEFARARSVFERALDVDSTYI 104 Query: 670 VLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEEL 729 L + + A + ++A+ P+ + + Q E Sbjct: 105 PLWLKYIECEMKNRNINHARNLFDRAVTQLPRVDKLWYKYVYMEEMLGNITGCRQVFERW 164 Query: 730 KQIVPKE 736 + P E Sbjct: 165 LKWEPDE 171 >3QOU-A nrPDB Length = 287 Score = 34.0 bits (76), Expect = 0.28, Method: Composition-based stats. Identities = 22/157 (14%), Positives = 51/157 (32%), Gaps = 4/157 (2%) Query: 580 QREHDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY 639 + + A+ + A Q+ LL + + A I + + Sbjct: 130 ESNYTDALPLLKDAWQLSNQNGEIGLLLAETLIALNRSEDA-EAVLKTIPLQDQDTRYQG 188 Query: 640 GLGMI-YYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI 698 + I KQ + Q+ + NP+ + L + + H + ++E+AL+ L + Sbjct: 189 LVAQIELLKQAADTPEIQQLQQQVAENPEDAALATQLALQLHQVGRNEEALELLFGHLRK 248 Query: 699 DPKNPLCKFHRA--SVLFANEKYKSALQELEELKQIV 733 D + + +L A + + + Sbjct: 249 DLTAADGQTRKTFQEILAALGTGDALASKYRRQLYAL 285 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 25/160 (15%), Positives = 58/160 (36%), Gaps = 2/160 (1%) Query: 618 DKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGV 677 ++A+ + +V PR M ++ ++ A + A ++ Q+ + + Sbjct: 102 EEAIRALLD--KVLPREEELKAQQAMQLMQESNYTDALPLLKDAWQLSNQNGEIGLLLAE 159 Query: 678 VQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKES 737 AL +SE A L + D L +Q+L++ P+++ Sbjct: 160 TLIALNRSEDAEAVLKTIPLQDQDTRYQGLVAQIELLKQAADTPEIQQLQQQVAENPEDA 219 Query: 738 LVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKE 777 + + ++G+ AL + D A+ Q ++ Sbjct: 220 ALATQLALQLHQVGRNEEALELLFGHLRKDLTAADGQTRK 259 >1ZU2-A nrPDB Length = 158 Score = 33.6 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 27/157 (17%), Positives = 52/157 (33%), Gaps = 36/157 (22%) Query: 545 HLQKDVALSVLSKDLTDMDKNSPEAWCAA----GNCFSLQREHD---------IAIKFFQ 591 + + + +D + K++P G L + H AI F+ Sbjct: 11 EFDRILLFEQIRQDAENTYKSNPLDADNLTRWGGVLLELSQFHSISDAKQMIQEAITKFE 70 Query: 592 RAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKF 651 A+ +DP A +G+ + + + P A + F Sbjct: 71 EALLIDPKKDEAVWCIGN-------------AYTSFAFLTPDETEA----------KHNF 107 Query: 652 SLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKA 688 LA FQ+A+D P ++ L + + A + +A Sbjct: 108 DLATQFFQQAVDEQPDNTHYLKSLEMTAKAPQLHAEA 144 >3ZN3-A nrPDB Length = 291 Score = 33.6 bits (75), Expect = 0.38, Method: Composition-based stats. Identities = 32/225 (14%), Positives = 70/225 (31%), Gaps = 25/225 (11%) Query: 488 LSHLPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRV-------EGMEIYS 540 + L +++ + RA + L ++ IF +R Y E + + Sbjct: 73 IYLLAKSYFDCK----EFERAAYTLQNCKSSKSIF--LRLYSKYLAGEKKSEEENETLLN 126 Query: 541 TTLWHLQKDVALSVLSKDLTDMDKN---SPEAWCAAGNCFSLQREHDIAIKFFQRAIQVD 597 T L + +S+ L + P +G + +++ AI F + + Sbjct: 127 TNLTLSSTNREFYYISEVLESLHYQGNKDPYLLYLSGVVYRKRKQDSKAIDFLKSCVLKA 186 Query: 598 PNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWY--GLGMIYYKQEKFSLAE 655 P + A+ +L + P + + + + S A Sbjct: 187 PFFWSAWL-------ELSLSIDSLETLTTVVSQLPSTHIMTKIFYVYASHELHQVNSSAY 239 Query: 656 MHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDP 700 +A I P S L ++ + + ++A + DP Sbjct: 240 EKLAEAEIIFPNSRYLKTQRALLTYDSRDFDEAESLFENILTNDP 284 >4I1A-A nrPDB Length = 391 Score = 32.8 bits (73), Expect = 0.69, Method: Composition-based stats. Identities = 25/144 (17%), Positives = 53/144 (36%), Gaps = 13/144 (9%) Query: 495 HYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEG-MEIYSTTLWHLQKDVALS 553 + +V + + YF ++ +A +IF E V + + L+ + AL Sbjct: 146 FFKVSYVYYYMKQTYFSMNYANRALKIFREYEEYAVQTVRCQFIVAGNLIDSLEYERALE 205 Query: 554 VLSKDLTDMDKNS------PEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYT-- 605 K L ++ K S + G C+ +E+ A + A+++ +++ Sbjct: 206 QFLKSL-EISKESNIEHLIAMSHMNIGICYDELKEYKKASQHLILALEIFEKSKHSFLTK 264 Query: 606 ---LLGHEFVLTEELDKALACFRN 626 L + + + AL FR Sbjct: 265 TLFTLTYVEAKQQNYNVALIYFRK 288 >4HNX-A nrPDB Length = 863 Score = 32.5 bits (72), Expect = 0.89, Method: Composition-based stats. Identities = 21/147 (14%), Positives = 51/147 (34%), Gaps = 13/147 (8%) Query: 611 FVLTEELDKALACFRNAI-RVNPRHYNAWYGL---GMIYYKQEKFSLAEMHFQKALDINP 666 + + L + + P ++ + L IY K + A + ++ + NP Sbjct: 213 YKAASDNQDKLQNVLKHLNDIEPCVFDKFGLLERKATIYMKLGQLKDASIVYRTLIKRNP 272 Query: 667 QSSVLLCHIGVVQHALKKSEKALDTLNKAI--VIDPKNPLCKFHRASVLFANEKYKSALQ 724 + + V + L KA+ ++ P C+ + L + + + Sbjct: 273 DNFKYYKLLEVSLGIQGD-----NKLKKALYGKLEQFYPRCEPPKFIPLTFLQDKEELSK 327 Query: 725 ELEE--LKQIVPKESLVYFLIGKVYKK 749 +L E L Q+ + + +Y++ Sbjct: 328 KLREYVLPQLERGVPATFSNVKPLYQR 354 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 15/124 (12%), Positives = 44/124 (35%), Gaps = 3/124 (2%) Query: 642 GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVI--- 698 + Y+ +++ + L + L G+ +++ + + A + AI Sbjct: 27 ALKLYEGKQYKKSLKLLDAILKKDGSHVDSLALKGLDLYSVGEKDDAASYVANAIRKIEG 86 Query: 699 DPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALM 758 +P+C + ++YK +++ +Y + + ++G AL+ Sbjct: 87 ASASPICCHVLGIYMRNTKEYKESIKWFTAALNNGSTNKQIYRDLATLQSQIGDFKNALV 146 Query: 759 NFSW 762 + Sbjct: 147 SRKK 150 >6N3Q-F nrPDB Length = 193 Score = 32.1 bits (71), Expect = 0.96, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 43/126 (34%), Gaps = 14/126 (11%) Query: 642 GMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHAL--------------KKSEK 687 GM +Q+K + A + A+++ + + L K + Sbjct: 65 GMKNLQQKKLNEALKNVSLAIEMAQRKRAPWEAFAIQLPELHFMLRSKIDLCLILGKHLE 124 Query: 688 ALDTLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVYFLIGKVY 747 AL L+ + P +A L +++ A E + P++ + L+ + Sbjct: 125 ALQDLDFLLGTGLIQPDVFVRKADCLLKLRQWEEARATCERGLALAPEDMKLRALLIETA 184 Query: 748 KKLGQT 753 + L + Sbjct: 185 RNLAEY 190 >4JCS-A nrPDB Length = 286 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 24/184 (13%), Positives = 60/184 (32%), Gaps = 9/184 (4%) Query: 523 SEVRRIENYRVEGMEIYSTTLWHLQKDVALSVLSKDLTDMDKNSPEAWCAAGNCFSLQRE 582 + + + E T L ++ D + VL + + P ++CA GN L+ Sbjct: 40 NRAAKHNPFDAELRADLMTVLERVRDDADIRVL------VLTSHPGSFCAGGNLHVLRDN 93 Query: 583 HDIAIKFFQRAIQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLG 642 D ++Q+ I+ + + LG + + A F ++ + + Sbjct: 94 LDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFALSLTADIVLASPRARFS 153 Query: 643 MIYYKQEKFSL--AEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN-KAIVID 699 M Y + A +A+ + ++ + + ++ +A+ Sbjct: 154 MAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVMEVHESEALEQR 213 Query: 700 PKNP 703 + Sbjct: 214 AREI 217 >4MBG-A nrPDB Length = 367 Score = 31.7 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 16/57 (28%), Positives = 22/57 (38%) Query: 594 IQVDPNYAYAYTLLGHEFVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEK 650 I P Y A + L E ++AL + I +NP HY W I + K Sbjct: 47 ISYSPEYLEATSYLRAVMAANEMSERALRLTGDIISMNPAHYTVWIYRAKILFALGK 103 >2BED-A nrPDB Length = 313 Score = 30.9 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 44/110 (40%), Gaps = 2/110 (1%) Query: 631 NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALD 690 + + + + + + E+ A + A+++N + + V+ +L+K + Sbjct: 40 SEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEM 99 Query: 691 TLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740 AI+ + +H VL K QELE + I+ +++ Y Sbjct: 100 NYITAIIEEQPKNYQVWHHRRVLVEW--LKDPSQELEFIADILNQDAKNY 147 >1O1S-A nrPDB Length = 380 Score = 30.9 bits (68), Expect = 2.6, Method: Composition-based stats. Identities = 19/110 (17%), Positives = 44/110 (40%), Gaps = 2/110 (1%) Query: 631 NPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALD 690 + + + + + + E+ A + A+++N + + V+ +L+K + Sbjct: 96 SEKFRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLRSLQKDLQEEM 155 Query: 691 TLNKAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740 AI+ + +H VL K QELE + I+ +++ Y Sbjct: 156 NYITAIIEEQPKNYQVWHHRRVLVEW--LKDPSQELEFIADILNQDAKNY 203 >3U48-A nrPDB Length = 775 Score = 30.5 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 31/147 (21%), Positives = 51/147 (34%), Gaps = 9/147 (6%) Query: 661 ALDINPQSSVLLCHIGVVQHALKKSEKALDTLNKAIVIDPKNPLCKFHRASVLFANEKYK 720 A +I QS VLL + V K AL + P + + K+ Sbjct: 357 AREIAAQSFVLLKNDNNVLPLKKSGTIAL--------VGP-LADNRVNMPGTWSVAAKHA 407 Query: 721 SALQELEELKQIVPKESLVYFLIGKVYKKLGQTHLALMNFSWAMDLDPKGANNQIKEAID 780 ++ LE LK+ ++ + + G + F + DP+ + IKEA+D Sbjct: 408 ESVSLLEGLKKAAGNDARILYAHGSNLDEDKSLIERATMFGKTLKYDPRPKDVVIKEAVD 467 Query: 781 KRYLPDDEEPITQEEQIMGTDESQESS 807 D E M + S S+ Sbjct: 468 IANQADVIVAALGESAEMSGEASSRSN 494 >4IN3-B nrPDB Length = 739 Score = 30.5 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 27/165 (16%), Positives = 50/165 (30%), Gaps = 17/165 (10%) Query: 491 LPSHHYNTGWVLCQIGRAYFELSEYMQAERIFSEVRRIENYRVEGMEIYSTTLWHLQKDV 550 P+H N + E+ ++ R++ +E L + Sbjct: 257 APTHVLNPSLTNNYLVETLVEIVRLTKSL---EACRKMLKKLIEIHPEAVIILIRVYFAC 313 Query: 551 ALSVLSKDLTDMDKNSPEAWCAAGNCFSLQREHDIAIKFFQRAIQVDPNYAYAYTLLGHE 610 L + + DL + NSP ++ A + I + F + + + Sbjct: 314 DLEIDAVDLINEQLNSPSSFLA-----DDSKTSHIQLIFKSELLSIQSEFL--------- 359 Query: 611 FVLTEELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAE 655 + + A A+ P + WY L IY K S A Sbjct: 360 LDVKRDYKLAKEVAMEAVNCAPNEFKTWYLLTRIYIKLNDMSNAL 404 >3LY9-A nrPDB Length = 372 Score = 30.5 bits (67), Expect = 3.3, Method: Composition-based stats. Identities = 10/58 (17%), Positives = 22/58 (37%), Gaps = 1/58 (1%) Query: 615 EELDKALACFRNAIRVNPRHYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLL 672 + D++ I + N + LG +Y + A + A ++ P ++ L Sbjct: 291 GKTDESYQAINTGIDLEMSWLN-YVLLGKVYEMKGMNREAANAYLTAFNLRPGANTLY 347 >2H6F-A nrPDB Length = 382 Score = 29.8 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 41/107 (38%), Gaps = 2/107 (1%) Query: 634 HYNAWYGLGMIYYKQEKFSLAEMHFQKALDINPQSSVLLCHIGVVQHALKKSEKALDTLN 693 + + + + E+ A + A+++N + + V+ +L+K Sbjct: 96 FRDVYDYFRAVLQRDERSERAFKLTRDAIELNAANYTVWHFRRVLLKSLQKDLHEEMNYI 155 Query: 694 KAIVIDPKNPLCKFHRASVLFANEKYKSALQELEELKQIVPKESLVY 740 AI+ + +H VL + QELE + I+ +++ Y Sbjct: 156 TAIIEEQPKNYQVWHHRRVLVEW--LRDPSQELEFIADILNQDAKNY 200 >6QGL-A nrPDB Length = 512 Score = 29.4 bits (64), Expect = 6.8, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 26/60 (43%) Query: 763 AMDLDPKGANNQIKEAIDKRYLPDDEEPITQEEQIMGTDESQESSMTDADDTQLHAAESD 822 A L P NQ+ +++ KR + + + + G + + + A +L+A S+ Sbjct: 38 AEGLTPDVLRNQLSDSVVKRKSNNQSTMVDNQNILDGVEHTAYTEAKIAAIEELNAGSSE 97 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.123 0.325 Lambda K H 0.267 0.0387 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,903,753 Number of Sequences: 36641 Number of extensions: 1122117 Number of successful extensions: 3779 Number of sequences better than 10.0: 105 Number of HSP's better than 10.0 without gapping: 90 Number of HSP's successfully gapped in prelim test: 78 Number of HSP's that attempted gapping in prelim test: 3151 Number of HSP's gapped (non-prelim): 469 length of query: 824 length of database: 10,336,785 effective HSP length: 105 effective length of query: 719 effective length of database: 6,489,480 effective search space: 4665936120 effective search space used: 4665936120 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 63 (29.0 bits)