BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P30084 (290 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2HW5-A nrPDB 538 e-153 2DUB-A nrPDB 493 e-140 3H81-A nrPDB 275 2e-74 3MOY-A nrPDB 260 6e-70 4FZW-A nrPDB 222 1e-58 5ZAI-A nrPDB 218 2e-57 5Z7R-A nrPDB 199 1e-51 5JBW-A nrPDB 144 3e-35 2PPY-A nrPDB 125 1e-29 2IEX-A nrPDB 124 7e-29 5WYB-B nrPDB 123 8e-29 1EF9-A nrPDB 122 2e-28 5VE2-A nrPDB 122 3e-28 3T88-A nrPDB 120 1e-27 4JWV-A nrPDB 119 1e-27 6OJM-A nrPDB 115 2e-26 2VSU-C nrPDB 114 4e-26 5KJP-A nrPDB 113 1e-25 4EML-A nrPDB 111 4e-25 2UZF-A nrPDB 109 1e-24 4FZW-C nrPDB 108 3e-24 5YLO-A nrPDB 105 2e-23 1NZY-B nrPDB 105 2e-23 4JFC-A nrPDB 104 4e-23 4JCS-A nrPDB 103 7e-23 3HE2-A nrPDB 100 1e-21 3OME-A nrPDB 99 3e-21 6IUM-B nrPDB 98 4e-21 4J2U-A nrPDB 96 1e-20 3BPT-A nrPDB 96 1e-20 5ZRV-A nrPDB 96 2e-20 3T8B-A nrPDB 94 5e-20 3HIN-A nrPDB 92 2e-19 3ZWA-A nrPDB 91 5e-19 4ZU2-A nrPDB 86 2e-17 2D3T-A nrPDB 86 2e-17 4IZC-A nrPDB 84 9e-17 3I47-A nrPDB 82 4e-16 4HDT-A nrPDB 81 5e-16 3LAO-A nrPDB 80 1e-15 2WTB-A nrPDB 79 2e-15 4Q1J-A nrPDB 77 8e-15 5MRE-88 nrPDB 77 9e-15 2A81-A nrPDB 77 1e-14 2NP9-A nrPDB 73 2e-13 4JSB-A nrPDB 71 6e-13 3JU1-A nrPDB 69 2e-12 3HP0-A nrPDB 63 2e-10 4B3J-A nrPDB 59 2e-09 1XX4-A nrPDB 59 3e-09 3M6N-A nrPDB 56 2e-08 4HC8-A nrPDB 48 5e-06 4ZDC-A nrPDB 44 7e-05 5A1W-H nrPDB 30 0.95 1ASO-A nrPDB 30 1.6 4U1Y-A nrPDB 27 8.1 5ID2-B nrPDB 27 8.6 >2HW5-A nrPDB Length = 286 Score = 538 bits (1385), Expect = e-153, Method: Compositional matrix adjust. Identities = 262/267 (98%), Positives = 264/267 (98%) Query: 24 WRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVG 83 ++ ASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALK FEEDPAVG Sbjct: 20 FQSMASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVG 79 Query: 84 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 143 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC Sbjct: 80 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 139 Query: 144 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA Sbjct: 140 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 199 Query: 204 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF 263 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF Sbjct: 200 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF 259 Query: 264 YSTFATDDRKEGMTAFVEKRKANFKDQ 290 YSTFATDDRKEGMTAFVEKRKANFKDQ Sbjct: 260 YSTFATDDRKEGMTAFVEKRKANFKDQ 286 >2DUB-A nrPDB Length = 261 Score = 493 bits (1268), Expect = e-140, Method: Compositional matrix adjust. Identities = 235/261 (90%), Positives = 253/261 (96%) Query: 30 GANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG 89 GANF+YII EK+GKN++VGLIQLNRPKALNALC+GLI+ELNQAL+TFEEDPAVGAIVLTG Sbjct: 1 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 60 Query: 90 GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMC 149 G+KAFAAGADIKEMQN +FQDCYS KFL HWDH+T++KKPVIAAVNGYA GGGCELAMMC Sbjct: 61 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 120 Query: 150 DIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 DIIYAGEKAQF QPEIL+GTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV Sbjct: 121 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 180 Query: 210 SKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFAT 269 SKI PVETLVEEAIQCAEKIA+NSKI+VAMAKESVNAAFEMTLTEG+KLEKKLFYSTFAT Sbjct: 181 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 240 Query: 270 DDRKEGMTAFVEKRKANFKDQ 290 DDR+EGM+AFVEKRKANFKD Sbjct: 241 DDRREGMSAFVEKRKANFKDH 261 >3H81-A nrPDB Length = 278 Score = 275 bits (702), Expect = 2e-74, Method: Compositional matrix adjust. Identities = 129/256 (50%), Positives = 181/256 (70%), Gaps = 3/256 (1%) Query: 32 NFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGD 91 +E I+ E+ + VG+I LNRP+ALNAL +++E+ A ++DP +GAI++TG Sbjct: 23 TYETILVER---DQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSA 79 Query: 92 KAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDI 151 KAFAAGADIKEM +L+F D +++ F W L V+ P IAAV GYA GGGCELAMMCD+ Sbjct: 80 KAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDV 139 Query: 152 IYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 211 + A + A+F QPEI +G +PG GG+QRLTRA+GK+ AM+++LTG + A +A+++GLVS+ Sbjct: 140 LIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSR 199 Query: 212 ICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD 271 + P + L+ EA A I+ S MAKE+VN AFE +L+EG E++LF+S FAT+D Sbjct: 200 VVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATED 259 Query: 272 RKEGMTAFVEKRKANF 287 + EGM AF+EKR F Sbjct: 260 QSEGMAAFIEKRAPQF 275 >3MOY-A nrPDB Length = 263 Score = 260 bits (664), Expect = 6e-70, Method: Compositional matrix adjust. Identities = 125/244 (51%), Positives = 171/244 (70%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNL 106 VGLI+L+RP ALNAL L E+ A + F+ D +GAIV+TG ++AFAAGADI EM L Sbjct: 20 VGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTGSERAFAAGADIAEMVTL 79 Query: 107 SFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEIL 166 + L WD LTQV+KP++AAV GYA GGGCELAM+CD++ A + A+F QPEI Sbjct: 80 TPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAMLCDLVIAADTARFGQPEIT 139 Query: 167 IGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCA 226 +G +PG GGTQRLTRAVGK+ AM++ LTG ++A++A++ GLVS+I P L++EA+ A Sbjct: 140 LGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLVSRIVPAADLLDEALAVA 199 Query: 227 EKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKAN 286 ++IA S+ K+++N AFE L+ G + E+ FY+ F T D+ EGMTAF+EKR Sbjct: 200 QRIARMSRPAGRAVKDAINEAFERPLSAGMRYERDAFYAMFDTHDQTEGMTAFLEKRTPE 259 Query: 287 FKDQ 290 F D+ Sbjct: 260 FTDR 263 >4FZW-A nrPDB Length = 258 Score = 222 bits (566), Expect = 1e-58, Method: Compositional matrix adjust. Identities = 112/246 (45%), Positives = 160/246 (65%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 + V L+ LNRP A NAL + L+ +L L+ D ++ V+TG + FAAGAD+ E Sbjct: 11 RQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNE 70 Query: 103 MQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQ 162 M + + W L KP+IAAVNGYA G GCELA++CD++ AGE A+F Sbjct: 71 MAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGL 130 Query: 163 PEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEA 222 PEI +G +PGAGGTQRL R+VGKSLA +MVL+G+ I+AQ A+QAGLVS + P + +E A Sbjct: 131 PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYA 190 Query: 223 IQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEK 282 +Q A K+A +S + + AK+++ + E+ L G E++LF AT+DR EG++AF++K Sbjct: 191 LQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQK 250 Query: 283 RKANFK 288 R +FK Sbjct: 251 RTPDFK 256 >5ZAI-A nrPDB Length = 259 Score = 218 bits (556), Expect = 2e-57, Method: Compositional matrix adjust. Identities = 118/258 (45%), Positives = 163/258 (63%), Gaps = 5/258 (1%) Query: 33 FEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDK 92 FE I +K G + I LNRP LNAL L++EL++A+ E DP + I++TG K Sbjct: 3 FETIETKKEG---NLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKGK 59 Query: 93 AFAAGADIKEMQNLSFQDCY--SSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCD 150 AF AGADI + L+ + + S K + D + + KP IA +NGYA GGG ELA+ CD Sbjct: 60 AFCAGADITQFNQLTPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALACD 119 Query: 151 IIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 I A E+AQ PEI +G PG GGTQRLTR +GK A+EM++TGDRI +DA++ GLV+ Sbjct: 120 IRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLVN 179 Query: 211 KICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATD 270 ++ P+ L +E + AEKIA S I +A+ KE VN + L G LE + F+T+ Sbjct: 180 RVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFSTE 239 Query: 271 DRKEGMTAFVEKRKANFK 288 D+KEG++AF+EKR+ FK Sbjct: 240 DKKEGVSAFLEKREPTFK 257 >5Z7R-A nrPDB Length = 267 Score = 199 bits (507), Expect = 1e-51, Method: Compositional matrix adjust. Identities = 109/259 (42%), Positives = 161/259 (62%), Gaps = 7/259 (2%) Query: 36 IIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAF 94 +I EK GK V ++ +NRPKALNAL + E++ + E D V A++LTG G+K+F Sbjct: 6 VILEKEGK---VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSF 62 Query: 95 AAGADIKEMQNLSFQDCYSSKFL--KHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDII 152 AGADI EM+ ++ + L K + L ++KPVIAAVNG+A GGGCE+AM CDI Sbjct: 63 VAGADISEMKEMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIR 122 Query: 153 YAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 A A+F QPE+ +G PG GGTQRL+R VG +A +++ T I A +A + GLV+K+ Sbjct: 123 IASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKV 182 Query: 213 CPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDR 272 L+ A + A KI SN+ + V ++K+++N + + E + F F+T+D+ Sbjct: 183 VEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFSTEDQ 242 Query: 273 KEGMTAFVEKRK-ANFKDQ 290 K+ MTAF+EKRK FK++ Sbjct: 243 KDAMTAFIEKRKIEGFKNR 261 >5JBW-A nrPDB Length = 260 Score = 144 bits (364), Expect = 3e-35, Method: Compositional matrix adjust. Identities = 84/235 (35%), Positives = 128/235 (54%), Gaps = 3/235 (1%) Query: 59 NALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIKEMQNLSFQD--CYSSK 115 NA+ ++ EL + + V A+V+TG GDKAF AGAD+KE ++ + + Sbjct: 26 NAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGADLKERATMAEDEVRAFLDG 85 Query: 116 FLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGG 175 + + + + IAA+NG A GGG ELA+ CD+ A A+ E+ +G IPG GG Sbjct: 86 LRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAPAAELGLTEVKLGIIPGGGG 145 Query: 176 TQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKI 235 TQRL R VG A +++LT RI+A +A GL +++ P L+ A AE + N+ I Sbjct: 146 TQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEGHLLAVAYGLAESVVENAPI 205 Query: 236 VVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ 290 VA AK +++ + L + LE + + T+DR EG+ AF EKR +K + Sbjct: 206 AVATAKHAIDEGTGLELDDALALELRKYEEILKTEDRLEGLRAFAEKRAPVYKGR 260 >2PPY-A nrPDB Length = 265 Score = 125 bits (315), Expect = 1e-29, Method: Compositional matrix adjust. Identities = 75/225 (33%), Positives = 129/225 (57%), Gaps = 4/225 (1%) Query: 68 ELNQALKTFEEDPAVGA-IVLTGGDKAFAAGADIKEMQNLS--FQDCYSSKFLKHWDHLT 124 E N A+ DP + IV++ K F+AGADI +++ F+ + + D + Sbjct: 39 EFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADINFLRSADPRFKTQFCLFCNETLDKIA 98 Query: 125 QVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA-QFAQPEILIGTIPGAGGTQRLTRAV 183 + + IA + G+ GGG E+A+ CD+ + G++A + PE+ +G + G GGTQRL R + Sbjct: 99 RSPQVYIACLEGHTVGGGLEMALACDLRFMGDEAGKIGLPEVSLGVLAGTGGTQRLARLI 158 Query: 184 GKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKES 243 G S A++M +TG+ I+ Q+A + GLV+++ P E + A K+A+++ V+ K + Sbjct: 159 GYSRALDMNITGETITPQEALEIGLVNRVFPQAETRERTREYARKLANSATYAVSNIKLA 218 Query: 244 VNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFK 288 + EM L + E +L F ++D KEG++AF+EKR+ N+K Sbjct: 219 IMNGKEMPLNVAIRYEGELQNLLFRSEDAKEGLSAFLEKRQPNWK 263 >2IEX-A nrPDB Length = 272 Score = 124 bits (310), Expect = 7e-29, Method: Compositional matrix adjust. Identities = 90/262 (34%), Positives = 135/262 (51%), Gaps = 12/262 (4%) Query: 32 NFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-G 90 ++E II E N + I +NRP+ NA ++E+ A +D +G I+LTG G Sbjct: 10 DYEDIIYETY---NGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAG 66 Query: 91 DKAFAAGADIKEMQNLSF--QDCYSSKFLKHWDHLTQV-KKPVIAAVNGYAFGGGCELAM 147 KAF +G D K + + +D + L +V KPVIA V GYA GGG L + Sbjct: 67 GKAFCSGGDQKVRGHGGYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLHV 126 Query: 148 MCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 +CD+ A + A F Q +G+ G G L R VG A E+ + +AQ+A + G Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEALEMG 186 Query: 208 LVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE--MTLTEGSKLEKKLFYS 265 LV+K+ P+E L EE ++ A++I S + K + NA + + + + LFY+ Sbjct: 187 LVNKVVPLEQLEEETVKWAQEILEKSPTAIRFLKAAFNADSDGLAGIQQLAGDATLLFYT 246 Query: 266 TFATDDRKEGMTAFVEKRKANF 287 T++ KEGM AF EKRK +F Sbjct: 247 ---TEEAKEGMRAFKEKRKPDF 265 >5WYB-B nrPDB Length = 280 Score = 123 bits (309), Expect = 8e-29, Method: Compositional matrix adjust. Identities = 84/250 (33%), Positives = 126/250 (50%), Gaps = 4/250 (1%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIK 101 K+ LI +N P A D LI L Q ++ D + A+V+TG G K F+AGAD+ Sbjct: 23 KHGHTALITINHPPANTWDRDSLIG-LRQLIEHLNRDDDIYALVVTGQGPKFFSAGADLN 81 Query: 102 EMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 + + +F + ++ L + IAA+NGYA GGG E A+ CDI A +AQ Sbjct: 82 MFADGDKARAREMARRFGEAFEALRDFRGVSIAAINGYAMGGGLECALACDIRIAERQAQ 141 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 A PE +G +P AGGTQ L VG+ A M+L +R+ A+ A + GLV ++ Sbjct: 142 MALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIGLVEQVVDSGEAR 201 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 A+ A K+A S + + K + A E E++ F F D +EG+ AF Sbjct: 202 GAALLLAAKVARQSPVAIRTIKPLIQGARERAPNTWLPEERERFVDLFDAQDTREGVNAF 261 Query: 280 VEKRKANFKD 289 +EKR +++ Sbjct: 262 LEKRDPKWRN 271 >1EF9-A nrPDB Length = 261 Score = 122 bits (306), Expect = 2e-28, Method: Compositional matrix adjust. Identities = 79/253 (31%), Positives = 125/253 (49%), Gaps = 16/253 (6%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVL--TGGDKAFAAGADIKE 102 N V +I+ N + LNAL ID+L QAL P + I+L G K F+AG DI E Sbjct: 12 NKVAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPSGSKVFSAGHDIHE 70 Query: 103 MQN-----LSFQDCYSSKFLKHWDHLTQ-VKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 + + LS+ D L+ + Q KP+I+ V G +GG E+ M D+I A Sbjct: 71 LPSGGRDPLSYDDP-----LRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDLIIAAS 125 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 + F+ + +G G LTR G + E++ T I+AQ A G+++ + VE Sbjct: 126 TSTFSMTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGILNHVVEVE 185 Query: 217 TLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEK--KLFYSTFATDDRKE 274 L + +Q A I+ + + +A+ KE + E + E+ + + + ++D +E Sbjct: 186 ELEDFTLQMAHHISEKAPLAIAVIKEELRVLGEAHTMNSDEFERIQGMRRAVYDSEDYQE 245 Query: 275 GMTAFVEKRKANF 287 GM AF+EKRK NF Sbjct: 246 GMNAFLEKRKPNF 258 >5VE2-A nrPDB Length = 275 Score = 122 bits (305), Expect = 3e-28, Method: Compositional matrix adjust. Identities = 73/244 (29%), Positives = 129/244 (52%), Gaps = 1/244 (0%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM 103 NN V + +NRP+ NAL L L L+ D + A++LT F AG D+ + Sbjct: 32 NNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFTAGNDLDDF 91 Query: 104 QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQP 163 N ++ + ++ +++ + P++ AVNG A G G + + CD++YA + A+F P Sbjct: 92 IN-PVEESGTPSVIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDMVYASKSARFRAP 150 Query: 164 EILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAI 223 +G +P A + L AVG++ A +++L G + A++A AGLV+++ + LV E++ Sbjct: 151 FTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTRVFEDDVLVAESL 210 Query: 224 QCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKR 283 + AE++AS + V +K + + + K E +F A+ + KE + AF EKR Sbjct: 211 KIAEQVASLAPNSVKQSKRLIRGVNKEEVQAQMKREGVIFAEQLASAEFKESVAAFFEKR 270 Query: 284 KANF 287 +F Sbjct: 271 APHF 274 >3T88-A nrPDB Length = 289 Score = 120 bits (300), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 88/271 (32%), Positives = 134/271 (49%), Gaps = 14/271 (5%) Query: 24 WRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVG 83 W + G FE I EK + + I +NRP+ NA + E+ QAL D +G Sbjct: 19 WHDCSEG--FEDIRYEK--STDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIG 74 Query: 84 AIVLTG-GDKAFAAGADIKEMQNLS-FQDCYSSKFLKHWDHLTQVK---KPVIAAVNGYA 138 I+LTG GDKAF +G D K + ++D L D Q++ KPV+A V GY+ Sbjct: 75 VIILTGAGDKAFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYS 134 Query: 139 FGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRI 198 GGG L MMCD+ A + A F Q +G+ G G + R VG+ A E+ + Sbjct: 135 IGGGHVLHMMCDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQY 194 Query: 199 SAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE--MTLTEGS 256 A+ A GLV+ + P+ L +E ++ ++ NS + + K ++NA + L E + Sbjct: 195 DAKQALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELA 254 Query: 257 KLEKKLFYSTFATDDRKEGMTAFVEKRKANF 287 LFY T++ +EG AF +KR+ +F Sbjct: 255 GNATMLFY---MTEEGQEGRNAFNQKRQPDF 282 >4JWV-A nrPDB Length = 278 Score = 119 bits (299), Expect = 1e-27, Method: Compositional matrix adjust. Identities = 89/263 (33%), Positives = 135/263 (51%), Gaps = 15/263 (5%) Query: 27 FASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIV 86 F S A+ ++ I V ++LNRP+ LNA+ + D L A + + A+V Sbjct: 20 FQSMADIDFRI------EGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVV 73 Query: 87 LTG-GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCEL 145 L+ G+KAF GAD+ + L KKP++AAV G+ GGG EL Sbjct: 74 LSAEGEKAFCIGADVSGGAERKTRMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGGFEL 133 Query: 146 AMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 AM DII A + AQF PE +G I G R R + +A++++LTG+RI A +A+ Sbjct: 134 AMCADIIVAADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARH 193 Query: 206 AGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKES----VNAAFEMTLTEGSKLEKK 261 GLV+++ P L E A++ A K+ + S + V AK + + E+ L ++ E Sbjct: 194 YGLVNEVVPFAELEEAALRWASKLNAASPLAVQAAKAAALGRLGHPLEVALM--TRFEPI 251 Query: 262 LFYSTFATDDRKEGMTAFVEKRK 284 Y+ AT+D+KEG A E+RK Sbjct: 252 EEYA--ATEDKKEGERAAGERRK 272 >6OJM-A nrPDB Length = 286 Score = 115 bits (289), Expect = 2e-26, Method: Compositional matrix adjust. Identities = 87/269 (32%), Positives = 132/269 (49%), Gaps = 31/269 (11%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-------GDKAFA 95 K N V I NRP+ NA EL A EDP++G ++L+G G AF Sbjct: 25 KCNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEGPSPKDGGWAFC 84 Query: 96 AGADIKEMQNLSFQDCYSSKFLKHWDHLTQVK-------KPVIAAVNGYAFGGGCELAMM 148 +G D Q Y + +H ++ +V+ K VIA V G+A GGG L ++ Sbjct: 85 SGGD----QKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGGGHSLHVV 140 Query: 149 CDIIYAG-EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 CD+ A E A F Q + + + G G+ L + VG+ A E+ G SAQ+A + G Sbjct: 141 CDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSAQEAFEMG 200 Query: 208 LVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYS-- 265 +V+K+ P L + A + A++I + S + M K F M LT+ + +++F Sbjct: 201 MVNKVVPHAELEDTAYEWAQEILAKSPTSIRMLK------FAMNLTDDGMVGQQVFAGEA 254 Query: 266 ---TFATDDRKEGMTAFVEKRKANF-KDQ 290 + TD+ KEG AF+EKRK +F +DQ Sbjct: 255 TRLAYMTDEAKEGRNAFLEKRKPDFGEDQ 283 >2VSU-C nrPDB Length = 275 Score = 114 bits (285), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 76/246 (30%), Positives = 119/246 (48%), Gaps = 9/246 (3%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM--Q 104 + + LNRP+ NA+ L E+ L+T E+DPA G +VLTG +A+ AG D+KE + Sbjct: 19 IAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEYFRE 78 Query: 105 NLSFQDCYSSKFLK-----HWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 + + K + W L KP IA VNG+ FGGG + CD+ ++A Sbjct: 79 VDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLVACDLAICADEAT 138 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 F EI G PG ++ + VG ++ ++TG Q A + GLV++ P+ L Sbjct: 139 FGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLAQLR 198 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSK-LEKKLFYSTFA-TDDRKEGMT 277 E I+ A + + +V+ AK E+T + L KL S T R++GM Sbjct: 199 EVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTGGREQGMK 258 Query: 278 AFVEKR 283 F++ + Sbjct: 259 QFLDDK 264 >5KJP-A nrPDB Length = 265 Score = 113 bits (282), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 86/268 (32%), Positives = 133/268 (49%), Gaps = 27/268 (10%) Query: 31 ANFE-YIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG 89 AN E ++ E+R + + +I +NRPKA NA+ + L A+ + D + +LTG Sbjct: 11 ANTEPEVLVEQRDR---ILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAGLSVAILTG 67 Query: 90 GDKAFAAGADIK----------EMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAF 139 G +F AG D+K E + L F + +K P+IAAV GYA Sbjct: 68 GGGSFCAGMDLKAFARGENVVVEGRGLGFTERPPTK-------------PLIAAVEGYAL 114 Query: 140 GGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRIS 199 GG ELA+ D+I A + F PE+ G + G GG RL + ++AME+ LTGD + Sbjct: 115 AGGTELALAADLIVAARDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLP 174 Query: 200 AQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLE 259 A+ A + GLV+ + T ++ AI AEKI +N + V K + + + + Sbjct: 175 AERAHELGLVNVLAEPGTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQ 234 Query: 260 KKLFYSTFATDDRKEGMTAFVEKRKANF 287 K+ F ++D KEG AF E+R+ + Sbjct: 235 MKILVPVFTSNDAKEGAIAFAERRRPRW 262 >4EML-A nrPDB Length = 275 Score = 111 bits (277), Expect = 4e-25, Method: Compositional matrix adjust. Identities = 84/256 (32%), Positives = 124/256 (48%), Gaps = 14/256 (5%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG------GDKAFAA 96 K + I +NRP NA + EL A ED +G ++LTG G AF + Sbjct: 16 KAGGIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGPHSDGKYAFCS 75 Query: 97 GADIKEMQNLSFQDCYSSKFLKHWDH---LTQVKKPVIAAVNGYAFGGGCELAMMCDIIY 153 G D + D + L D + + K VIA V GYA GGG L ++CD+ Sbjct: 76 GGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGHVLHLVCDLTI 135 Query: 154 AGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIC 213 A + A F Q +G+ G G+ L R VG+ A E+ + SAQ+A++ G+V+ + Sbjct: 136 AADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEAERMGMVNTVV 195 Query: 214 PVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAF--EMTLTEGSKLEKKLFYSTFATDD 271 PV+ L EE IQ A++I S S + + K + NA + L E + L+Y T++ Sbjct: 196 PVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATLLYY---MTEE 252 Query: 272 RKEGMTAFVEKRKANF 287 EG AF+EKR +F Sbjct: 253 GSEGKQAFLEKRPPDF 268 >2UZF-A nrPDB Length = 273 Score = 109 bits (273), Expect = 1e-24, Method: Compositional matrix adjust. Identities = 79/243 (32%), Positives = 122/243 (50%), Gaps = 7/243 (2%) Query: 50 IQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIKEMQNLSF 108 + +NRP+ NA + E+ A +D V IVLTG GD AF +G D K+ + + Sbjct: 26 VTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVSVIVLTGEGDLAFCSGGDQKKRGHGGY 85 Query: 109 --QDCYSSKFLKHWDHLTQV-KKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEI 165 +D + L ++ KPVIA V GYA GGG L ++CD+ A + A F Q Sbjct: 86 VGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAVGGGNVLNVVCDLTIAADNAIFGQTGP 145 Query: 166 LIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQC 225 +G+ G+ L R VG A E+ + +AQ+A GLV+ + P+E + +E +Q Sbjct: 146 KVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYNAQEALDMGLVNTVVPLEKVEDETVQW 205 Query: 226 AEKIASNSKIVVAMAKESVNAAFE-MTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRK 284 ++I +S + K ++NA + + + + L Y T TD+ KEG AF EKR Sbjct: 206 CKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAGDATLLYYT--TDEAKEGRDAFKEKRD 263 Query: 285 ANF 287 +F Sbjct: 264 PDF 266 >4FZW-C nrPDB Length = 274 Score = 108 bits (270), Expect = 3e-24, Method: Compositional matrix adjust. Identities = 79/248 (31%), Positives = 128/248 (51%), Gaps = 14/248 (5%) Query: 50 IQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQ----- 104 + LNRP+ LN+ D + +L + LK E D + ++LTG + F AG D+ + Sbjct: 28 LTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLNDRNVDPTG 87 Query: 105 -----NLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 +S + Y+ + L ++ KPVI AVNG A G G LA+ DI+ A A+ Sbjct: 88 PAPDLGMSVERFYNPLVRR----LAKLPKPVICAVNGVAAGAGATLALGGDIVIAARSAK 143 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 F +G IP GGT L R G++ AM + L G+++SA+ A + G++ ++ ETL Sbjct: 144 FVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDDETLA 203 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 + A Q A +A+ + + K+++N+A TL LE+ + D +EG++AF Sbjct: 204 DTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREGVSAF 263 Query: 280 VEKRKANF 287 + KR F Sbjct: 264 LAKRSPQF 271 >5YLO-A nrPDB Length = 271 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 77/249 (30%), Positives = 112/249 (44%), Gaps = 5/249 (2%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNL 106 + + LNRP+ NAL ++ L+ L E DPAV A+VL G ++F AGAD+ E Sbjct: 15 IAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGADLAEWAAA 74 Query: 107 SFQDCYSSKFLKHWDH-----LTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFA 161 + S H L + KP +AAVNG A G G +LA+ CD A A+F Sbjct: 75 EARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAASARFK 134 Query: 162 QPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEE 221 + P AG + L R +G A ++ + SA+ A AGLV ++ E LVE Sbjct: 135 AGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLVGEVVADEHLVEA 194 Query: 222 AIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVE 281 A ++AS A K + +L E + E+ ++D E + A E Sbjct: 195 VGAFAARLASGPTFAFAQTKRLLRDGAGRSLAEQLRAEQAAGLLCGRSEDAAEALRAVAE 254 Query: 282 KRKANFKDQ 290 KR F + Sbjct: 255 KRSPQFSGR 263 >1NZY-B nrPDB Length = 269 Score = 105 bits (263), Expect = 2e-23, Method: Compositional matrix adjust. Identities = 73/252 (28%), Positives = 126/252 (50%), Gaps = 11/252 (4%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM 103 + V I + P+ NAL + E+ AL EED +VGA+++TG + AF AG ++E+ Sbjct: 10 EDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLREI 69 Query: 104 Q----NLSFQDCYSSKFLKHWDH-----LTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA 154 +D + L W H + +VK+PV+AA+NG A GGG +++ D+ Sbjct: 70 PLDKGVAGVRDHFRIAAL--WWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAIC 127 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICP 214 + A+F IG + L R VG AME++LT + ++AK GLVS++ P Sbjct: 128 ADSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWGLVSRVYP 187 Query: 215 VETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE 274 + E A + A ++A+ + MAKE +A + + E ++ E + ++ Sbjct: 188 KDEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMP 247 Query: 275 GMTAFVEKRKAN 286 +T F++ +A+ Sbjct: 248 CLTRFLDGHRAD 259 >4JFC-A nrPDB Length = 281 Score = 104 bits (260), Expect = 4e-23, Method: Compositional matrix adjust. Identities = 75/245 (30%), Positives = 125/245 (51%), Gaps = 5/245 (2%) Query: 49 LIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSF 108 ++ L+ P+ NAL + +AL E +P + ++V+TG F AG +++ +Q Sbjct: 37 ILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGNLQRLQANRR 96 Query: 109 Q----DCYSSKFLKHW-DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQP 163 + S + L +W D + KPVIAAV G A G G LA+ CD + A A F Sbjct: 97 EAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVAASNAVFVMS 156 Query: 164 EILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAI 223 +G P GG+ L R++ ++LA E+++ G+RISAQ GLV+K+ + EA+ Sbjct: 157 YSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLVNKVASAGDALSEAL 216 Query: 224 QCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKR 283 + A ++ + + +A KE +N A TL++ E+ F + EG+ AF+ KR Sbjct: 217 RMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHHSNGGEGIAAFLGKR 276 Query: 284 KANFK 288 ++ Sbjct: 277 TPQYR 281 >4JCS-A nrPDB Length = 286 Score = 103 bits (258), Expect = 7e-23, Method: Compositional matrix adjust. Identities = 69/249 (27%), Positives = 124/249 (49%), Gaps = 5/249 (2%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQ 104 N VG I++NR N L +L L+ +D + +VLT +F AG ++ ++ Sbjct: 32 NNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHPGSFCAGGNLHVLR 91 Query: 105 -NLSFQDCYSSKFLK---HWDH-LTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 NL Y + +K + H + + +PVIAAV+G AFG G L++ DI+ A +A+ Sbjct: 92 DNLDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFALSLTADIVLASPRAR 151 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 F+ + +G +P G L RAVG A E++ + + A++A + GLV ++ E L Sbjct: 152 FSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVMEVHESEALE 211 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 + A + AE + + +A+ K ++N + + LE + F+T + + + A Sbjct: 212 QRAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLEAASQAAAFSTKEPRAAIEAL 271 Query: 280 VEKRKANFK 288 + K+ F+ Sbjct: 272 LSKQPPPFR 280 >3HE2-A nrPDB Length = 264 Score = 99.8 bits (247), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 78/259 (30%), Positives = 124/259 (47%), Gaps = 18/259 (6%) Query: 38 AEKRGKNNTVGL--------IQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG 89 A+ +G + +G+ I+L RP+ NAL L++EL QA++ D + AIVLTG Sbjct: 14 AQTQGPGSMIGITQAEAVLTIELQRPERRNALNSQLVEELTQAIRK-AGDGSARAIVLTG 72 Query: 90 GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMC 149 AF AGAD+ +F Y + ++ + PV+ A+NG A G G +LAM C Sbjct: 73 QGTAFCAGADLS---GDAFAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQC 129 Query: 150 DIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 D+ A F P G +RL+ VG A M+L+ ++++A+ A G+ Sbjct: 130 DLRVVAPDAFFQFPTSKYGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMA 189 Query: 210 SKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFAT 269 ++I TL + AE IA + + + AK +N + + E K+LF + + Sbjct: 190 NRIG---TLADAQAWAAE-IARLAPLAIQHAKRVLND--DGAIEEAWPAHKELFDKAWGS 243 Query: 270 DDRKEGMTAFVEKRKANFK 288 D E A +EKR F+ Sbjct: 244 QDVIEAQVARMEKRPPKFQ 262 >3OME-A nrPDB Length = 282 Score = 98.6 bits (244), Expect = 3e-21, Method: Compositional matrix adjust. Identities = 69/218 (31%), Positives = 112/218 (51%), Gaps = 13/218 (5%) Query: 42 GKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK 101 G +++ I LNRP+A NA L+DEL+ A ED V I+L K F+AG D++ Sbjct: 28 GVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILRANGKHFSAGHDLR 87 Query: 102 ------EMQNLSFQDCYSS-KFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA 154 E +L F + + ++L + V KP IAAV G GG L CD+I A Sbjct: 88 GGGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLCWPCDLILA 147 Query: 155 GEKAQFAQPEILIGTIPGAGGTQR--LTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 + A F+ P L+G GG + T +G A E++ TG ++A++A++ G+V+++ Sbjct: 148 SDDALFSDPVALMGI----GGVEYHGHTWELGPRKAKEILFTGRALTAEEAERTGMVNRV 203 Query: 213 CPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEM 250 + L + + AE+IA+ + AK +VN ++ Sbjct: 204 VARDELDAQTRELAEQIATMPPFALRQAKRAVNQTLDV 241 >6IUM-B nrPDB Length = 701 Score = 98.2 bits (243), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 67/193 (34%), Positives = 106/193 (54%), Gaps = 14/193 (7%) Query: 44 NNTVGLIQLNRPKALNALCD----GLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGAD 99 + V +I L+ P +N L G+++ + +AL +D AV AIV+TG KAF+ GAD Sbjct: 8 QDGVAVITLDNP-PVNGLGHSTRLGIVEGMTRAL----DDAAVKAIVITGAGKAFSGGAD 62 Query: 100 IKEMQN-LSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA 158 I+E + Q+ ++ L KPV+AAV+ A GGG ELA+ C+ A + A Sbjct: 63 IREFNTPKAMQEPTLHSVIRV---LEGSSKPVVAAVHSVAMGGGLELALGCNYRVASKGA 119 Query: 159 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETL 218 Q A PE+ +G +PGAGGTQRL R +G A M+++G + ++ L +I + L Sbjct: 120 QIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIVDGDVL 179 Query: 219 VEEAIQCAEKIAS 231 A++ A+ + + Sbjct: 180 -PAAVKFAQNVGA 191 >4J2U-A nrPDB Length = 365 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 60/180 (33%), Positives = 90/180 (50%), Gaps = 10/180 (5%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIK 101 K G I L+RP ALNAL ++ E++ AL+ + DP V +V+ G +AF AG DI Sbjct: 30 KVRRAGRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIA 89 Query: 102 EMQNLSF-------QDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA 154 E+ QD + ++ + D + KP+++ + G+ GGG L Sbjct: 90 ELHGRGVAGDHAFGQDFWRVEYRMN-DRIAAFPKPIVSLMQGFTMGGGVGLGCHARHRIV 148 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICP 214 GE +Q + PE IG +P GGT L RA G+ + + + LTG R+ DA AG + P Sbjct: 149 GETSQISMPECAIGLVPDVGGTHLLARAPGR-IGVWLGLTGARMGPGDAIFAGFADRFVP 207 >3BPT-A nrPDB Length = 363 Score = 96.3 bits (238), Expect = 1e-20, Method: Compositional matrix adjust. Identities = 65/183 (35%), Positives = 92/183 (50%), Gaps = 7/183 (3%) Query: 42 GKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADI 100 GK G+I LNRPK LNAL +I ++ LK +E+DP I++ G G KAF AG DI Sbjct: 11 GKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI 70 Query: 101 KEMQNL--SFQDCYSSKFLKHW---DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG 155 + + + Q F + + + + +KP +A ++G GGG L++ A Sbjct: 71 RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT 130 Query: 156 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV 215 EK FA PE IG P GG L R GK L + LTG R+ +D +AG+ + Sbjct: 131 EKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS 189 Query: 216 ETL 218 E L Sbjct: 190 EKL 192 >5ZRV-A nrPDB Length = 763 Score = 95.9 bits (237), Expect = 2e-20, Method: Compositional matrix adjust. Identities = 60/178 (33%), Positives = 96/178 (53%), Gaps = 7/178 (3%) Query: 42 GKNNTVGLIQLNRPKA-LNALCDGLIDELNQAL-KTFEEDPAVGAIVLTGGDKAFAAGAD 99 G V ++++N P + +N L L E ++ + + + D A++++ F AGAD Sbjct: 44 GVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIRSAVLISSKPGCFIAGAD 103 Query: 100 IKEM---QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCD--IIYA 154 I + + L S + + + L + KP++AA+NG GGG E+A+ C I Sbjct: 104 INMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCLGGGLEVAISCQYRIATK 163 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 K PE+L+G +PGAGGTQRL + VG A++M+LTG I A AK+ GLV ++ Sbjct: 164 DRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRSIRADRAKKMGLVDQL 221 >3T8B-A nrPDB Length = 334 Score = 94.4 bits (233), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 83/300 (27%), Positives = 127/300 (42%), Gaps = 41/300 (13%) Query: 18 PVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFE 77 P AWR G + I R ++ + NRP+ NA +DEL + L Sbjct: 39 PFDAKAWR-LVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHAR 97 Query: 78 EDPAVGAIVLTG-------GDKAFAAGADIKEMQNLSFQ----------DCYSSKFLKHW 120 P VG ++LTG G AF +G D + +Q D + L Sbjct: 98 MSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRL--- 154 Query: 121 DHLTQVK-------KPVIAAVNGYAFGGGCELAMMCDIIYAG-EKAQFAQPEILIGTIPG 172 H+ +V+ K VI VNG+A GGG L ++CD+ A E A+F Q + +G+ G Sbjct: 155 -HILEVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDG 213 Query: 173 AGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASN 232 G+ L R VG+ A E+ G +A+ Q G V+ + L +Q A +I + Sbjct: 214 GYGSAYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAK 273 Query: 233 SKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYS-----TFATDDRKEGMTAFVEKRKANF 287 S M K F L + + ++LF + TD+ EG AF++KR ++ Sbjct: 274 SPQAQRMLK------FAFNLLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDW 327 >3HIN-A nrPDB Length = 275 Score = 92.4 bits (228), Expect = 2e-19, Method: Compositional matrix adjust. Identities = 73/252 (28%), Positives = 120/252 (47%), Gaps = 11/252 (4%) Query: 45 NTVG---LIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK 101 +TVG I LNRPK NAL DGL+ L L + + A+V+ G F+AG D+ Sbjct: 21 DTVGPVLTIGLNRPKKRNALNDGLMAALKDCLTDIPDQ--IRAVVIHGIGDHFSAGLDLS 78 Query: 102 EMQNLSFQD--CYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 E++ + +S + + +D + + PVIAA+ G GGG ELA I A A Sbjct: 79 ELRERDATEGLVHSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLELACAAHIRVAEASAY 138 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 +A PE G G GG+ RL R +G + +M+LTG SA + G + + Sbjct: 139 YALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVVHGFSQYLIENGSAY 198 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDR--KEGMT 277 ++A++ ++A N+ + +++ E G +E +T A D+ K + Sbjct: 199 DKALELGNRVAQNAPLTNFAVLQALPMIAEANPQTGLLMES--LMATVAQSDQEAKTRIR 256 Query: 278 AFVEKRKANFKD 289 AF++ + A ++ Sbjct: 257 AFLDHKTAKVRE 268 >3ZWA-A nrPDB Length = 742 Score = 90.9 bits (224), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 84/276 (30%), Positives = 131/276 (47%), Gaps = 40/276 (14%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQ 104 +++ +I+L P +NA+ +I E+ L+ D V AIV+ G + F AGADI Sbjct: 29 HSLAMIRLCNP-PVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFS 87 Query: 105 NLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPE 164 + S D + + +KPV+AA+ G A GGG ELA+ C A KA+ PE Sbjct: 88 AFTPGLALGSLV----DEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPE 143 Query: 165 ILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQ 224 + +G +PGA GTQ L R VG +A++++ +G +SA +A + G++ + + VEEAI+ Sbjct: 144 VTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDP-VEEAIK 202 Query: 225 CAEKIAS-------------------NSKIVVAMAK---------------ESVNAAFEM 250 A+KI +S A+AK S+ A+ + Sbjct: 203 FAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKH 262 Query: 251 TLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKAN 286 G K E+KLF A+ K AF ++ AN Sbjct: 263 PYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSAN 298 >4ZU2-A nrPDB Length = 272 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 71/246 (28%), Positives = 110/246 (44%), Gaps = 17/246 (6%) Query: 50 IQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQ 109 I LNRP++ NA+ ++ EL L +D +V A+VL G D F AG DIK+M Sbjct: 20 ITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCAGGDIKDMAGARAA 79 Query: 110 DCYSSKFLKH-----WDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPE 164 + + L + + ++A V G GGG LA + D+ A AQF PE Sbjct: 80 GAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDVAIAAADAQFGLPE 139 Query: 165 ILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIC-----PVETLV 219 +G +P A + R +G + A + LT R ++A + GLV C +E + Sbjct: 140 TSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLV-HFCEADADALEQRL 197 Query: 220 EEAIQCAEKIASNSKIVV-AMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTA 278 EE ++ + A N+ A+ S + L + + + F + EG A Sbjct: 198 EETLEQLRRCAPNANAATKALLLASESGELGALLDDAA----RQFAEAVGGAEGSEGTLA 253 Query: 279 FVEKRK 284 FV+KRK Sbjct: 254 FVQKRK 259 >2D3T-A nrPDB Length = 715 Score = 85.5 bits (210), Expect = 2e-17, Method: Compositional matrix adjust. Identities = 54/195 (27%), Positives = 95/195 (48%), Gaps = 14/195 (7%) Query: 48 GLIQLN---RPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE-M 103 G+++L + +++N ++EL QA+ + D +V ++++ G F GADI E + Sbjct: 16 GIVELKFDLKGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFV 75 Query: 104 QNLSFQDCY-------SSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 +N D ++K ++ L P +AA+NG A GGG E+ + D + Sbjct: 76 ENFKLPDAELIAGNLEANKIFSDFEDLNV---PTVAAINGIALGGGLEMCLAADFRVMAD 132 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 A+ PE+ +G PG GGT RL R +G A+E + +G A+DA + V + + Sbjct: 133 SAKIGLPEVKLGIYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTAD 192 Query: 217 TLVEEAIQCAEKIAS 231 L A+ ++ S Sbjct: 193 KLGAAALDLIKRAIS 207 >4IZC-A nrPDB Length = 275 Score = 83.6 bits (205), Expect = 9e-17, Method: Compositional matrix adjust. Identities = 63/194 (32%), Positives = 93/194 (47%), Gaps = 6/194 (3%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 ++N V ++ LNRP NAL I+EL T V A+VLTG F AG D+ E Sbjct: 17 RDNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAGDHFCAGLDLVE 75 Query: 103 MQNLSFQ-DCYSSKFLKHWDHLTQVKK---PVIAAVNGYAFGGGCELAMMCDIIYAGEKA 158 D + L+ + +++ P+IAA+ G GGG LA + + Sbjct: 76 HWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQST 135 Query: 159 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETL 218 FA PE G G G T R++ +GK ++M+LTG Q+A GL I + Sbjct: 136 YFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSF 195 Query: 219 VEEAIQCAEKIASN 232 ++A++ A+KIASN Sbjct: 196 -DKAMELADKIASN 208 >3I47-A nrPDB Length = 268 Score = 81.6 bits (200), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 76/251 (30%), Positives = 121/251 (48%), Gaps = 11/251 (4%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNL 106 VGL+ +NR NA + L+ E+ L + D V IVL K F+AGAD+ MQ++ Sbjct: 14 VGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGADLTWMQSM 73 Query: 107 -------SFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 + +D L + ++Q KP IA V G AFGGG LA CDI A A+ Sbjct: 74 ANFTEEENLEDSLVLGNLMY--SISQSPKPTIAMVQGAAFGGGAGLAAACDIAIASTSAR 131 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 F E+ +G IP A + + RA+G+ A + ++ + A A LV P +TL+ Sbjct: 132 FCFSEVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVPDDTLL 190 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEG-SKLEKKLFYSTFATDDRKEGMTA 278 E ++ A +I++N+ V +K+ + E + L +D+ +EG+ A Sbjct: 191 EFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVRYTASLIAHKRVSDEGQEGLKA 250 Query: 279 FVEKRKANFKD 289 F+ K N+ + Sbjct: 251 FLNKEIPNWNE 261 >4HDT-A nrPDB Length = 353 Score = 81.3 bits (199), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 58/182 (31%), Positives = 94/182 (51%), Gaps = 11/182 (6%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIKEMQN 105 VGL+ LNRPKA+N+L G++ + + L +E D +V A++LTG G++ AG D+ + + Sbjct: 19 VGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGAGERGLCAGGDVVAIYH 78 Query: 106 LSFQDCYSSKFLKHW-------DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA 158 + D ++ + W H+ + KP ++ ++G GGG + ++ + Sbjct: 79 SAKADGAEAR--RFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVGVGAHGNVRVVTDTT 136 Query: 159 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETL 218 + A PE+ IG IP GGT L+RA GK L + LTG S DA G P + + Sbjct: 137 KMAMPEVGIGFIPDVGGTYLLSRAPGK-LGLHAALTGAPFSGADAIVMGFADHYVPHDKI 195 Query: 219 VE 220 E Sbjct: 196 DE 197 >3LAO-A nrPDB Length = 258 Score = 79.7 bits (195), Expect = 1e-15, Method: Compositional matrix adjust. Identities = 71/255 (27%), Positives = 120/255 (47%), Gaps = 20/255 (7%) Query: 36 IIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFA 95 + E+RG + LI L+R NA ++ +L A+ +E VL + F Sbjct: 14 VTREQRGH---LFLIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGEHFT 70 Query: 96 AGADIKEMQ----NLSFQDCYSSKFLKHWDHLTQVK-KPVIAAVNGYAFGGGCELAMMCD 150 AG D+ E+ F+ Y + W + + KP++ AV G + G EL + D Sbjct: 71 AGLDLMELAPKLAASGFR--YPDGGVDPWGVVQPRRSKPLVVAVQGTCWTAGIELMLNAD 128 Query: 151 IIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 I A +FA E+L G P G T R RA G + AM +LTGD A +A + L++ Sbjct: 129 IAVAARGTRFAHLEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLT 188 Query: 211 KICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEG-----SKLEKKLFYS 265 ++ + A++ AE+IA + + V + ++ +AF+ EG S++ + L + Sbjct: 189 EVVEPGEELARALEYAERIARAAPLAV---RAALQSAFQ-GRDEGDDAALSRVNESL-AA 243 Query: 266 TFATDDRKEGMTAFV 280 ++D +EG+ A V Sbjct: 244 LIGSEDVREGVLAMV 258 >2WTB-A nrPDB Length = 725 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 68/195 (34%), Positives = 97/195 (49%), Gaps = 6/195 (3%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK--- 101 + V +I L P +N+L ++ L + V AIV+TG F+ G DI Sbjct: 16 DGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 Query: 102 EMQNLSFQDCYSSKFLKHW--DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 EMQ + ++ + D L +KP +AA++G A GGG ELAM C + AQ Sbjct: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 PE+ +G IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P LV Sbjct: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 Query: 220 EEAIQCAEKIASNSK 234 A + A I K Sbjct: 195 TTARRWALDIVGRRK 209 >4Q1J-A nrPDB Length = 268 Score = 77.0 bits (188), Expect = 8e-15, Method: Compositional matrix adjust. Identities = 58/219 (26%), Positives = 105/219 (47%), Gaps = 9/219 (4%) Query: 59 NALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLK 118 NA L D+L QA + ++P A++LTG D FA+G + + L Q + KF Sbjct: 46 NAFSQELTDDLIQAFEYIRQNPKYKAVILTGYDNYFASGGTQEGL--LRIQQGLT-KFTD 102 Query: 119 HWDHLTQV----KKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAG 174 D+L + + PVIAA+ G+ GGG + + DI+ ++ + + G PG G Sbjct: 103 --DNLYSLALDCEIPVIAAMQGHGIGGGFVMGLFADIVILSRESVYTANFMKYGFTPGMG 160 Query: 175 GTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSK 234 T + + +G SLA E++L D ++ G+ K+ P +++ A++ A+++A + Sbjct: 161 ATFIVPKKLGFSLAQEILLNAGSYRGADLEKRGVPFKVLPRAEVLDYAVELAQELAEKPR 220 Query: 235 IVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRK 273 + K+ + A L + E + TF ++ K Sbjct: 221 NSLVTLKDHLVAPLRDQLPRVIEQELMMAEKTFHHEEVK 259 >5MRE-88 nrPDB Length = 457 Score = 77.0 bits (188), Expect = 9e-15, Method: Compositional matrix adjust. Identities = 53/192 (27%), Positives = 85/192 (44%), Gaps = 23/192 (11%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDK--AFAAGADIKE 102 +T +I LNRPK LNAL + + + + L + + ++L ++ +F AG D+ Sbjct: 10 DTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDVAT 69 Query: 103 MQNLSFQ-----------DCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDI 151 + +F D YS F + KP++ ++G GGG L++ Sbjct: 70 VAIFNFNKEFAKSIKFFTDEYSLNF-----QIATYLKPIVTFMDGITMGGGVGLSIHTPF 124 Query: 152 IYAGEKAQFAQPEILIGTIPGAGGTQRLTRAV-----GKSLAMEMVLTGDRISAQDAKQA 206 A E ++A PE+ IG P G T L R V +A+ + LTG+ ++ DA Sbjct: 125 RIATENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYML 184 Query: 207 GLVSKICPVETL 218 GL S E L Sbjct: 185 GLASHYVSSENL 196 >2A81-A nrPDB Length = 250 Score = 76.6 bits (187), Expect = 1e-14, Method: Compositional matrix adjust. Identities = 64/233 (27%), Positives = 102/233 (43%), Gaps = 5/233 (2%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAFAAGADIK 101 ++ V +I L+ P N L + AL D +V A+V+ GG +++F+AG D Sbjct: 6 NSDEVRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGDFN 65 Query: 102 EMQNLSFQDC---YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA 158 E++ LS + + + + + + V KP IAAV+GYA G G + A+M D A Sbjct: 66 EVKQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMASTA 125 Query: 159 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETL 218 F PE+ G I + G L G S E++ + A LV+++ L Sbjct: 126 NFVMPELKHG-IGCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESSAL 184 Query: 219 VEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD 271 ++ AI A +AS K +VN F L + K + + F D Sbjct: 185 LDAAITQAHVMASYPASAFINTKRAVNKPFIHLLEQTRDASKAVHKAAFQARD 237 >2NP9-A nrPDB Length = 440 Score = 72.8 bits (177), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 55/203 (27%), Positives = 94/203 (46%), Gaps = 28/203 (13%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG---------DKA 93 + + V + + R LNA +D++ A+ DP V +L GG + Sbjct: 173 RRDGVARLTMCRDDRLNAEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRV 232 Query: 94 FAAGADIKEMQN--LSFQDCYSSKFLKH----------------WDHLTQVKKPVIAAVN 135 F+AG ++K + +S D + L + W H +++KP +AAV+ Sbjct: 233 FSAGINLKYLSQGGISLVDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVD 292 Query: 136 GYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTG 195 G+A GGG +L ++ D + A A F+ P G IPGA RL R G ++ +++L G Sbjct: 293 GFAIGGGAQLLLVFDRVLASSDAYFSLPAAKEGIIPGAANL-RLGRFAGPRVSRQVILEG 351 Query: 196 DRISAQDAKQAGLVSKICPVETL 218 RI A++ + LV ++ + L Sbjct: 352 RRIWAKEPEARLLVDEVVEPDEL 374 >4JSB-A nrPDB Length = 296 Score = 70.9 bits (172), Expect = 6e-13, Method: Compositional matrix adjust. Identities = 58/191 (30%), Positives = 84/191 (43%), Gaps = 25/191 (13%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM 103 + V I L+RP NA+ + EL + T + AV +V+TG F++G D+ Sbjct: 43 DGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQ--AVRIVVITGEGPTFSSGIDLDMF 100 Query: 104 Q-----------NLSFQDCYSSKFLKH----------WDHLTQVKKPVIAAVNGYAFGGG 142 Q L +D S+ L W L + IAAV G+A G G Sbjct: 101 QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLW--LRRADIVSIAAVRGHAIGAG 158 Query: 143 CELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQD 202 +LA+ CDI + AQ E +G +P GTQ L VG + A+E+ LT I A + Sbjct: 159 FQLALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVGVNRAIELCLTARTIDAAE 218 Query: 203 AKQAGLVSKIC 213 A Q L ++ Sbjct: 219 AAQLRLAERVV 229 >3JU1-A nrPDB Length = 407 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 56/177 (31%), Positives = 85/177 (48%), Gaps = 21/177 (11%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIKEMQN 105 VG++ LN KALNAL ++ + L +++DP + +VL G G+KAF AG D++ + + Sbjct: 52 VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPLIACVVLDGSGEKAFCAGGDVRALYH 111 Query: 106 LS--------------FQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDI 151 S F++ Y +L H KPV+ +G GGG L Sbjct: 112 ASVAAKGQVTEVAKVFFEEEYRLDYLLH-----TYGKPVLVWGDGIVMGGGLGLMAGASH 166 Query: 152 IYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 E ++ A PE+ IG P GG+ L R GK + + + LT ++A DA GL Sbjct: 167 KVVTETSRIAMPEVTIGLYPDVGGSYFLNRMPGK-MGLFLGLTAYHMNAADACYVGL 222 >3HP0-A nrPDB Length = 267 Score = 62.8 bits (151), Expect = 2e-10, Method: Compositional matrix adjust. Identities = 53/168 (31%), Positives = 71/168 (42%), Gaps = 6/168 (3%) Query: 46 TVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE--- 102 +V I +RP+A N + D LI+E Q L E V +VL G + F GAD +E Sbjct: 16 SVCYITFHRPEANNTINDTLIEECLQVLNQCETS-TVTVVVLEGLPEVFCFGADFQEIYQ 74 Query: 103 -MQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFA 161 M+ Q W L I+ V G GG DI A + A F+ Sbjct: 75 EMKRGRKQASSQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSATDIAIADQTASFS 134 Query: 162 QPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 E+L G P A L R +G+ A M L IS Q+A + GL+ Sbjct: 135 LSELLFGLYP-ACVLPFLIRRIGRQKAHYMTLMTKPISVQEASEWGLI 181 >4B3J-A nrPDB Length = 736 Score = 59.3 bits (142), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 55/174 (31%), Positives = 82/174 (47%), Gaps = 10/174 (5%) Query: 59 NALCDGLIDELNQAL-KTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYS---- 113 N + + I+ + +A+ + E ++ +V+ K F AG D+K M +D Sbjct: 44 NVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVKTMIQARPEDAGDVFNT 103 Query: 114 -SKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE--KAQFAQPEILIGTI 170 + L + KPV+AA+NG A GGG E+A+ C A + +Q PE+ +G + Sbjct: 104 VETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAADVKGSQLGLPEVTLGLL 163 Query: 171 PGAGGTQRLTRAVGKSLAMEMVLT-GDRISAQDAKQAGLVSK-ICPVETLVEEA 222 PG GG R R G A VL G R AK+ GLV + + VE LV A Sbjct: 164 PGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELVATVEELVPAA 217 >1XX4-A nrPDB Length = 261 Score = 58.9 bits (141), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 56/254 (22%), Positives = 108/254 (42%), Gaps = 7/254 (2%) Query: 36 IIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKA-F 94 ++ EK G+ + +++ P +N+L + E +L+ E D ++ ++LT F Sbjct: 6 VLVEKEGEAG-IAVMKFKNP-PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIF 63 Query: 95 AAGADIKEM--QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCD-- 150 +AG D+ EM +N + Y + W L +I+A+NG + GGC +A+ CD Sbjct: 64 SAGLDLMEMYGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYR 123 Query: 151 IIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 I+ K E L+G + +G A + G +A + GLV Sbjct: 124 IMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVD 183 Query: 211 KICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATD 270 ++ P + + +A K + + K + A L + + + + F S + D Sbjct: 184 EVVPEDQVHSKARSVMAKWFTIPDHSRQLTKSMMRKATADNLIKQREADIQNFTSFISRD 243 Query: 271 DRKEGMTAFVEKRK 284 ++ + ++EK K Sbjct: 244 SIQKSLHVYLEKLK 257 >3M6N-A nrPDB Length = 305 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 34/112 (30%), Positives = 53/112 (47%), Gaps = 7/112 (6%) Query: 131 IAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAME 190 IA V G A GGG E A+ C I A E PE+L PG G + + + LA + Sbjct: 144 IALVQGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQK 203 Query: 191 MVLTGDRISAQDAKQAGLVSKICP-------VETLVEEAIQCAEKIASNSKI 235 ++L G+ SA+ GLV ++ P VE ++ E+ + A+ ++ Sbjct: 204 IMLEGNLYSAEQLLGMGLVDRVVPRGQGVAAVEQVIRESKRTPHAWAAMQQV 255 >4HC8-A nrPDB Length = 255 Score = 48.1 bits (113), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 55/196 (28%), Positives = 86/196 (43%), Gaps = 16/196 (8%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 + +++ +I ++ K +NAL + LN A+ + D VGA+V+TG + F+ G D+K Sbjct: 11 RKDSIAVISMDDGK-VNALGPAMQQALNAAIDNADRDD-VGALVITGNGRVFSGGFDLKI 68 Query: 103 MQNLSFQ---DCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 + + Q D F + L KPV+ A G+A G L D A Sbjct: 69 LTSGEVQPAIDMLRGGFELAY-RLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYN 127 Query: 160 FAQPEILIG-TIPGAG---GTQRLTR-AVGKSLAMEMVLTGDRISAQDAKQAGLVSKICP 214 E+ IG TIP A RLTR A ++ + G + A AG + +I Sbjct: 128 IQANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFG-----ETALAAGFIDEIAL 182 Query: 215 VETLVEEAIQCAEKIA 230 E +V A + A + A Sbjct: 183 PEVVVSRAEEAAREFA 198 >4ZDC-A nrPDB Length = 300 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 42/177 (23%), Positives = 71/177 (40%), Gaps = 14/177 (7%) Query: 49 LIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSF 108 +I L P LNAL L + L+ + + V ++ + F++GAD K + Sbjct: 41 IIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 100 Query: 109 QDCY-----SSKFLKHW--------DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA- 154 D +SK++ ++ D + K +I +NG A G L +CDI+Y+ Sbjct: 101 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 160 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 211 +K P +G I G T L G + E ++ + G +SK Sbjct: 161 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISK 217 >5A1W-H nrPDB Length = 511 Score = 30.4 bits (67), Expect = 0.95, Method: Compositional matrix adjust. Identities = 26/93 (27%), Positives = 44/93 (47%), Gaps = 4/93 (4%) Query: 185 KSLAMEMVLTGDRISAQDAKQAGLVSKICP--VETLVEEAI--QCAEKIASNSKIVVAMA 240 + L M ++ T + +D + L S++ P L E I C + I + +IV Sbjct: 62 EKLYMVLITTKNSNILEDLETLRLFSRVIPEYCRALEENEISEHCFDLIFAFDEIVALGY 121 Query: 241 KESVNAAFEMTLTEGSKLEKKLFYSTFATDDRK 273 +E+VN A T TE E+K+F + T +R+ Sbjct: 122 RENVNLAQIRTFTEMDSHEEKVFRAVRETQERE 154 >1ASO-A nrPDB Length = 552 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 34/84 (40%), Gaps = 12/84 (14%) Query: 9 SCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGK-------NNTVGLIQLNRPKALNAL 61 S + P PP + PAW F NF Y I G N + L LN +N Sbjct: 302 SVSKLPTSPPPQTPAWDDFDRSKNFTYRITAAMGSPKPPVKFNRRIFL--LNTQNVINGY 359 Query: 62 CDGLIDELNQALKTFEEDPAVGAI 85 I++++ AL P +GA+ Sbjct: 360 VKWAINDVSLALP---PTPYLGAM 380 >4U1Y-A nrPDB Length = 819 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 14/45 (31%), Positives = 22/45 (48%), Gaps = 2/45 (4%) Query: 87 LTGGD--KAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKP 129 T GD K GA++ Q + + D SKF++ W L + + P Sbjct: 218 FTDGDLLKIQFGGAEVSGFQIVDYDDSLVSKFIERWSTLEEKEYP 262 >5ID2-B nrPDB Length = 164 Score = 27.3 bits (59), Expect = 8.6, Method: Compositional matrix adjust. Identities = 13/49 (26%), Positives = 21/49 (42%) Query: 41 RGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG 89 RG ++ + P A +C G +D+L L FE D + + G Sbjct: 35 RGYRGAKNVLLVFFPLAFTGICQGELDQLRDHLPEFENDDSAALAISVG 83 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2HW5-A nrPDB 359 e-99 2DUB-A nrPDB 344 3e-95 5ZAI-A nrPDB 302 1e-82 3H81-A nrPDB 285 2e-77 5Z7R-A nrPDB 279 9e-76 2IEX-A nrPDB 278 2e-75 3MOY-A nrPDB 276 7e-75 3T88-A nrPDB 276 9e-75 4FZW-A nrPDB 271 3e-73 4EML-A nrPDB 262 8e-71 2UZF-A nrPDB 254 3e-68 3T8B-A nrPDB 245 1e-65 6OJM-A nrPDB 244 3e-65 2PPY-A nrPDB 244 3e-65 1EF9-A nrPDB 240 6e-64 5VE2-A nrPDB 235 2e-62 5WYB-B nrPDB 234 3e-62 5JBW-A nrPDB 228 2e-60 4JCS-A nrPDB 224 4e-59 4FZW-C nrPDB 223 8e-59 4JWV-A nrPDB 222 1e-58 2VSU-C nrPDB 221 4e-58 5YLO-A nrPDB 220 6e-58 4JFC-A nrPDB 216 9e-57 1NZY-B nrPDB 213 8e-56 3HIN-A nrPDB 212 1e-55 3I47-A nrPDB 211 3e-55 3OME-A nrPDB 209 2e-54 2A81-A nrPDB 207 5e-54 3HE2-A nrPDB 205 1e-53 5KJP-A nrPDB 201 3e-52 1XX4-A nrPDB 200 5e-52 4IZC-A nrPDB 194 4e-50 3LAO-A nrPDB 185 1e-47 4ZU2-A nrPDB 185 2e-47 6IUM-B nrPDB 183 9e-47 3ZWA-A nrPDB 182 1e-46 3BPT-A nrPDB 178 3e-45 5ZRV-A nrPDB 176 8e-45 4Q1J-A nrPDB 176 1e-44 5MRE-88 nrPDB 165 1e-41 2WTB-A nrPDB 165 2e-41 4J2U-A nrPDB 161 4e-40 4JSB-A nrPDB 160 8e-40 2D3T-A nrPDB 158 3e-39 3HP0-A nrPDB 152 1e-37 4HDT-A nrPDB 148 3e-36 2NP9-A nrPDB 146 1e-35 4HC8-A nrPDB 138 3e-33 3JU1-A nrPDB 138 4e-33 4B3J-A nrPDB 131 3e-31 4ZDC-A nrPDB 128 2e-30 3M6N-A nrPDB 110 7e-25 Sequences not found previously or not previously below threshold: 3BF0-A nrPDB 42 4e-04 1V3M-A nrPDB 33 0.10 1QDB-A nrPDB 33 0.21 3SN5-A nrPDB 32 0.35 4KWB-A nrPDB 31 0.58 3RST-A nrPDB 31 0.58 3MH6-A nrPDB 31 0.71 3U9S-B nrPDB 30 1.7 6MZL-P nrPDB 30 1.7 1ON3-A nrPDB 30 1.8 1BH8-B nrPDB 30 1.9 3EEQ-A nrPDB 29 2.2 2YJN-B nrPDB 29 2.7 1A6E-A nrPDB 28 3.4 2C8T-A nrPDB 28 3.9 6B5B-F nrPDB 28 4.9 2GQD-A nrPDB 28 5.3 3QWD-A nrPDB 28 5.6 5Z9A-A nrPDB 27 8.4 1PWH-A nrPDB 27 9.7 >2HW5-A nrPDB Length = 286 Score = 359 bits (921), Expect = e-99, Method: Composition-based stats. Identities = 262/267 (98%), Positives = 264/267 (98%) Query: 24 WRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVG 83 ++ ASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALK FEEDPAVG Sbjct: 20 FQSMASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKIFEEDPAVG 79 Query: 84 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 143 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC Sbjct: 80 AIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGC 139 Query: 144 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA Sbjct: 140 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 199 Query: 204 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF 263 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF Sbjct: 200 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLF 259 Query: 264 YSTFATDDRKEGMTAFVEKRKANFKDQ 290 YSTFATDDRKEGMTAFVEKRKANFKDQ Sbjct: 260 YSTFATDDRKEGMTAFVEKRKANFKDQ 286 >2DUB-A nrPDB Length = 261 Score = 344 bits (882), Expect = 3e-95, Method: Composition-based stats. Identities = 235/261 (90%), Positives = 253/261 (96%) Query: 30 GANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG 89 GANF+YII EK+GKN++VGLIQLNRPKALNALC+GLI+ELNQAL+TFEEDPAVGAIVLTG Sbjct: 1 GANFQYIITEKKGKNSSVGLIQLNRPKALNALCNGLIEELNQALETFEEDPAVGAIVLTG 60 Query: 90 GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMC 149 G+KAFAAGADIKEMQN +FQDCYS KFL HWDH+T++KKPVIAAVNGYA GGGCELAMMC Sbjct: 61 GEKAFAAGADIKEMQNRTFQDCYSGKFLSHWDHITRIKKPVIAAVNGYALGGGCELAMMC 120 Query: 150 DIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 DIIYAGEKAQF QPEIL+GTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV Sbjct: 121 DIIYAGEKAQFGQPEILLGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 180 Query: 210 SKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFAT 269 SKI PVETLVEEAIQCAEKIA+NSKI+VAMAKESVNAAFEMTLTEG+KLEKKLFYSTFAT Sbjct: 181 SKIFPVETLVEEAIQCAEKIANNSKIIVAMAKESVNAAFEMTLTEGNKLEKKLFYSTFAT 240 Query: 270 DDRKEGMTAFVEKRKANFKDQ 290 DDR+EGM+AFVEKRKANFKD Sbjct: 241 DDRREGMSAFVEKRKANFKDH 261 >5ZAI-A nrPDB Length = 259 Score = 302 bits (773), Expect = 1e-82, Method: Composition-based stats. Identities = 118/261 (45%), Positives = 164/261 (62%), Gaps = 5/261 (1%) Query: 32 NFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGD 91 FE I +K G + I LNRP LNAL L++EL++A+ E DP + I++TG Sbjct: 2 EFETIETKKEG---NLFWITLNRPDKLNALNAKLLEELDRAVSQAESDPEIRVIIITGKG 58 Query: 92 KAFAAGADIKEMQNLSFQDCY--SSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMC 149 KAF AGADI + L+ + + S K + D + + KP IA +NGYA GGG ELA+ C Sbjct: 59 KAFCAGADITQFNQLTPAEAWKFSKKGREIMDKIEALSKPTIAMINGYALGGGLELALAC 118 Query: 150 DIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 DI A E+AQ PEI +G PG GGTQRLTR +GK A+EM++TGDRI +DA++ GLV Sbjct: 119 DIRIAAEEAQLGLPEINLGIYPGYGGTQRLTRVIGKGRALEMMMTGDRIPGKDAEKYGLV 178 Query: 210 SKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFAT 269 +++ P+ L +E + AEKIA S I +A+ KE VN + L G LE + F+T Sbjct: 179 NRVVPLANLEQETRKLAEKIAKKSPISLALIKEVVNRGLDSPLLSGLALESVGWGVVFST 238 Query: 270 DDRKEGMTAFVEKRKANFKDQ 290 +D+KEG++AF+EKR+ FK + Sbjct: 239 EDKKEGVSAFLEKREPTFKGK 259 >3H81-A nrPDB Length = 278 Score = 285 bits (729), Expect = 2e-77, Method: Composition-based stats. Identities = 129/259 (49%), Positives = 182/259 (70%), Gaps = 3/259 (1%) Query: 32 NFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGD 91 +E I+ E ++ VG+I LNRP+ALNAL +++E+ A ++DP +GAI++TG Sbjct: 23 TYETILVE---RDQRVGIITLNRPQALNALNSQVMNEVTSAATELDDDPDIGAIIITGSA 79 Query: 92 KAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDI 151 KAFAAGADIKEM +L+F D +++ F W L V+ P IAAV GYA GGGCELAMMCD+ Sbjct: 80 KAFAAGADIKEMADLTFADAFTADFFATWGKLAAVRTPTIAAVAGYALGGGCELAMMCDV 139 Query: 152 IYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSK 211 + A + A+F QPEI +G +PG GG+QRLTRA+GK+ AM+++LTG + A +A+++GLVS+ Sbjct: 140 LIAADTAKFGQPEIKLGVLPGMGGSQRLTRAIGKAKAMDLILTGRTMDAAEAERSGLVSR 199 Query: 212 ICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDD 271 + P + L+ EA A I+ S MAKE+VN AFE +L+EG E++LF+S FAT+D Sbjct: 200 VVPADDLLTEARATATTISQMSASAARMAKEAVNRAFESSLSEGLLYERRLFHSAFATED 259 Query: 272 RKEGMTAFVEKRKANFKDQ 290 + EGM AF+EKR F + Sbjct: 260 QSEGMAAFIEKRAPQFTHR 278 >5Z7R-A nrPDB Length = 267 Score = 279 bits (714), Expect = 9e-76, Method: Composition-based stats. Identities = 108/259 (41%), Positives = 159/259 (61%), Gaps = 7/259 (2%) Query: 36 IIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGD-KAF 94 +I EK GK V ++ +NRPKALNAL + E++ + E D V A++LTG K+F Sbjct: 6 VILEKEGK---VAVVTINRPKALNALNSDTLKEMDYVIGEIENDSEVLAVILTGAGEKSF 62 Query: 95 AAGADIKEMQNLSFQDCYSSKFL--KHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDII 152 AGADI EM+ ++ + L K + L ++KPVIAAVNG+A GGGCE+AM CDI Sbjct: 63 VAGADISEMKEMNTIEGRKFGILGNKVFRRLELLEKPVIAAVNGFALGGGCEIAMSCDIR 122 Query: 153 YAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 A A+F QPE+ +G PG GGTQRL+R VG +A +++ T I A +A + GLV+K+ Sbjct: 123 IASSNARFGQPEVGLGITPGFGGTQRLSRLVGMGMAKQLIFTAQNIKADEALRIGLVNKV 182 Query: 213 CPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDR 272 L+ A + A KI SN+ + V ++K+++N + + E + F F+T+D+ Sbjct: 183 VEPSELMNTAKEIANKIVSNAPVAVKLSKQAINRGMQCDIDTALAFESEAFGECFSTEDQ 242 Query: 273 KEGMTAFVEKRK-ANFKDQ 290 K+ MTAF+EKRK FK++ Sbjct: 243 KDAMTAFIEKRKIEGFKNR 261 >2IEX-A nrPDB Length = 272 Score = 278 bits (710), Expect = 2e-75, Method: Composition-based stats. Identities = 90/263 (34%), Positives = 134/263 (50%), Gaps = 12/263 (4%) Query: 32 NFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-G 90 ++E II E N + I +NRP+ NA ++E+ A +D +G I+LTG G Sbjct: 10 DYEDIIYETY---NGIAKITINRPEVHNAFRPKTVNEMIDAFTKARDDSNIGVIILTGAG 66 Query: 91 DKAFAAGADIKEMQNLSF--QDCYSSKFLKHWDHLTQV-KKPVIAAVNGYAFGGGCELAM 147 KAF +G D K + + +D + L +V KPVIA V GYA GGG L + Sbjct: 67 GKAFCSGGDQKVRGHGGYVGEDEIPRLNVLDLQRLIRVIPKPVIAMVAGYAIGGGHVLHV 126 Query: 148 MCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 +CD+ A + A F Q +G+ G G L R VG A E+ + +AQ+A + G Sbjct: 127 VCDLTIAADNAIFGQTGPKVGSFDGGYGAGYLARIVGHKKAREIWYLCRQYTAQEALEMG 186 Query: 208 LVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE--MTLTEGSKLEKKLFYS 265 LV+K+ P+E L EE ++ A++I S + K + NA + + + + LFY Sbjct: 187 LVNKVVPLEQLEEETVKWAQEILEKSPTAIRFLKAAFNADSDGLAGIQQLAGDATLLFY- 245 Query: 266 TFATDDRKEGMTAFVEKRKANFK 288 T++ KEGM AF EKRK +F Sbjct: 246 --TTEEAKEGMRAFKEKRKPDFS 266 >3MOY-A nrPDB Length = 263 Score = 276 bits (707), Expect = 7e-75, Method: Composition-based stats. Identities = 127/261 (48%), Positives = 174/261 (66%) Query: 30 GANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG 89 G+ Y VGLI+L+RP ALNAL L E+ A + F+ D +GAIV+TG Sbjct: 3 GSMTTYTTIATSRPVAGVGLIRLDRPDALNALNQTLEAEVLDAARDFDADLEIGAIVVTG 62 Query: 90 GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMC 149 ++AFAAGADI EM L+ L WD LTQV+KP++AAV GYA GGGCELAM+C Sbjct: 63 SERAFAAGADIAEMVTLTPHQARERNLLSGWDSLTQVRKPIVAAVAGYALGGGCELAMLC 122 Query: 150 DIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLV 209 D++ A + A+F QPEI +G +PG GGTQRLTRAVGK+ AM++ LTG ++A++A++ GLV Sbjct: 123 DLVIAADTARFGQPEITLGILPGLGGTQRLTRAVGKAKAMDLCLTGRSLTAEEAERVGLV 182 Query: 210 SKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFAT 269 S+I P L++EA+ A++IA S+ K+++N AFE L+ G + E+ FY+ F T Sbjct: 183 SRIVPAADLLDEALAVAQRIARMSRPAGRAVKDAINEAFERPLSAGMRYERDAFYAMFDT 242 Query: 270 DDRKEGMTAFVEKRKANFKDQ 290 D+ EGMTAF+EKR F D+ Sbjct: 243 HDQTEGMTAFLEKRTPEFTDR 263 >3T88-A nrPDB Length = 289 Score = 276 bits (705), Expect = 9e-75, Method: Composition-based stats. Identities = 85/272 (31%), Positives = 130/272 (47%), Gaps = 14/272 (5%) Query: 24 WRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVG 83 W + G FE I EK + + I +NRP+ NA + E+ QAL D +G Sbjct: 19 WHDCSEG--FEDIRYEK--STDGIAKITINRPQVRNAFRPLTVKEMIQALADARYDDNIG 74 Query: 84 AIVLTGGD-KAFAAGADIKEMQN-LSFQDCYSSKFLKHWD---HLTQVKKPVIAAVNGYA 138 I+LTG KAF +G D K + ++D L D + KPV+A V GY+ Sbjct: 75 VIILTGAGDKAFCSGGDQKVRGDYGGYKDDSGVHHLNVLDFQRQIRTCPKPVVAMVAGYS 134 Query: 139 FGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRI 198 GGG L MMCD+ A + A F Q +G+ G G + R VG+ A E+ + Sbjct: 135 IGGGHVLHMMCDLTIAADNAIFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQY 194 Query: 199 SAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE--MTLTEGS 256 A+ A GLV+ + P+ L +E ++ ++ NS + + K ++NA + L E + Sbjct: 195 DAKQALDMGLVNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELA 254 Query: 257 KLEKKLFYSTFATDDRKEGMTAFVEKRKANFK 288 LFY T++ +EG AF +KR+ +F Sbjct: 255 GNATMLFY---MTEEGQEGRNAFNQKRQPDFS 283 >4FZW-A nrPDB Length = 258 Score = 271 bits (692), Expect = 3e-73, Method: Composition-based stats. Identities = 112/248 (45%), Positives = 161/248 (64%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 + V L+ LNRP A NAL + L+ +L L+ D ++ V+TG + FAAGAD+ E Sbjct: 11 RQQRVLLLTLNRPAARNALNNALLMQLVNELEAAATDTSISVCVITGNARFFAAGADLNE 70 Query: 103 MQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQ 162 M + + W L KP+IAAVNGYA G GCELA++CD++ AGE A+F Sbjct: 71 MAEKDLAATLNDTRPQLWARLQAFNKPLIAAVNGYALGAGCELALLCDVVVAGENARFGL 130 Query: 163 PEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEA 222 PEI +G +PGAGGTQRL R+VGKSLA +MVL+G+ I+AQ A+QAGLVS + P + +E A Sbjct: 131 PEITLGIMPGAGGTQRLIRSVGKSLASKMVLSGESITAQQAQQAGLVSDVFPSDLTLEYA 190 Query: 223 IQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEK 282 +Q A K+A +S + + AK+++ + E+ L G E++LF AT+DR EG++AF++K Sbjct: 191 LQLASKMARHSPLALQAAKQALRQSQEVALQAGLAQERQLFTLLAATEDRHEGISAFLQK 250 Query: 283 RKANFKDQ 290 R +FK + Sbjct: 251 RTPDFKGR 258 >4EML-A nrPDB Length = 275 Score = 262 bits (671), Expect = 8e-71, Method: Composition-based stats. Identities = 84/267 (31%), Positives = 127/267 (47%), Gaps = 17/267 (6%) Query: 33 FEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDK 92 ++ I+ K G + I +NRP NA + EL A ED +G ++LTG Sbjct: 9 YDDILYYKAG---GIAKIVINRPHKRNAFRPQTVFELYDAFCNAREDNRIGVVLLTGAGP 65 Query: 93 A------FAAGADIKEMQNLSFQDCYSSKFLKHWDH---LTQVKKPVIAAVNGYAFGGGC 143 F +G D + D + L D + + K VIA V GYA GGG Sbjct: 66 HSDGKYAFCSGGDQSVRGEGGYIDDQGTPRLNVLDLQRLIRSMPKVVIALVAGYAIGGGH 125 Query: 144 ELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDA 203 L ++CD+ A + A F Q +G+ G G+ L R VG+ A E+ + SAQ+A Sbjct: 126 VLHLVCDLTIAADNAIFGQTGPKVGSFDGGFGSSYLARIVGQKKAREIWYLCRQYSAQEA 185 Query: 204 KQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE--MTLTEGSKLEKK 261 ++ G+V+ + PV+ L EE IQ A++I S S + + K + NA + L E + Sbjct: 186 ERMGMVNTVVPVDRLEEEGIQWAKEILSKSPLAIRCLKAAFNADCDGQAGLQELAGNATL 245 Query: 262 LFYSTFATDDRKEGMTAFVEKRKANFK 288 L+Y T++ EG AF+EKR +F Sbjct: 246 LYY---MTEEGSEGKQAFLEKRPPDFS 269 >2UZF-A nrPDB Length = 273 Score = 254 bits (650), Expect = 3e-68, Method: Composition-based stats. Identities = 80/270 (29%), Positives = 125/270 (46%), Gaps = 15/270 (5%) Query: 24 WRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVG 83 W +Y E + + +NRP+ NA + E+ A +D V Sbjct: 6 WETLREYDEIKYEFYE------GIAKVTINRPEVRNAFTPKTVAEMIDAFSRARDDQNVS 59 Query: 84 AIVLTGGDK-AFAAGADIKEMQNLSF--QDCYSSKFLKHWDHLTQV-KKPVIAAVNGYAF 139 IVLTG AF +G D K+ + + +D + L ++ KPVIA V GYA Sbjct: 60 VIVLTGEGDLAFCSGGDQKKRGHGGYVGEDQIPRLNVLDLQRLIRIIPKPVIAMVKGYAV 119 Query: 140 GGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRIS 199 GGG L ++CD+ A + A F Q +G+ G+ L R VG A E+ + + Sbjct: 120 GGGNVLNVVCDLTIAADNAIFGQTGPKVGSFDAGYGSGYLARIVGHKKAREIWYLCRQYN 179 Query: 200 AQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFE--MTLTEGSK 257 AQ+A GLV+ + P+E + +E +Q ++I +S + K ++NA + L + + Sbjct: 180 AQEALDMGLVNTVVPLEKVEDETVQWCKEIMKHSPTALRFLKAAMNADTDGLAGLQQMAG 239 Query: 258 LEKKLFYSTFATDDRKEGMTAFVEKRKANF 287 L+Y TD+ KEG AF EKR +F Sbjct: 240 DATLLYY---TTDEAKEGRDAFKEKRDPDF 266 >3T8B-A nrPDB Length = 334 Score = 245 bits (626), Expect = 1e-65, Method: Composition-based stats. Identities = 77/292 (26%), Positives = 120/292 (41%), Gaps = 23/292 (7%) Query: 18 PVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFE 77 P AWR G + I R ++ + NRP+ NA +DEL + L Sbjct: 39 PFDAKAWR-LVDGFDDLTDITYHRHVDDATVRVAFNRPEVRNAFRPHTVDELYRVLDHAR 97 Query: 78 EDPAVGAIVLTG-------GDKAFAAGADIKEMQNLSFQ-------------DCYSSKFL 117 P VG ++LTG G AF +G D + +Q L Sbjct: 98 MSPDVGVVLLTGNGPSPKDGGWAFCSGGDQRIRGRSGYQYASGDTADTVDVARAGRLHIL 157 Query: 118 KHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEK-AQFAQPEILIGTIPGAGGT 176 + + + K VI VNG+A GGG L ++CD+ A + A+F Q + +G+ G G+ Sbjct: 158 EVQRLIRFMPKVVICLVNGWAAGGGHSLHVVCDLTLASREYARFKQTDADVGSFDGGYGS 217 Query: 177 QRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIV 236 L R VG+ A E+ G +A+ Q G V+ + L +Q A +I + S Sbjct: 218 AYLARQVGQKFAREIFFLGRTYTAEQMHQMGAVNAVAEHAELETVGLQWAAEINAKSPQA 277 Query: 237 VAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFK 288 M K + N + L + + TD+ EG AF++KR ++ Sbjct: 278 QRMLKFAFN-LLDDGLVGQQLFAGEATRLAYMTDEAVEGRDAFLQKRPPDWS 328 >6OJM-A nrPDB Length = 286 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 81/269 (30%), Positives = 129/269 (47%), Gaps = 15/269 (5%) Query: 32 NFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-- 89 +E I +K N V I NRP+ NA EL A EDP++G ++L+G Sbjct: 17 EYEDITYKK---CNGVARIAFNRPEIRNAFRPKTTSELYDAFYDAYEDPSIGVVLLSGEG 73 Query: 90 -----GDKAFAAGADIKEMQNLSFQDC---YSSKFLKHWDHLTQVKKPVIAAVNGYAFGG 141 G AF +G D K + + + L+ + + K VIA V G+A GG Sbjct: 74 PSPKDGGWAFCSGGDQKARGHQGYVGEDGRHRLNILEVQRLIRFMPKVVIAVVPGWAVGG 133 Query: 142 GCELAMMCDIIYAG-EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISA 200 G L ++CD+ A E A F Q + + + G G+ L + VG+ A E+ G SA Sbjct: 134 GHSLHVVCDLTLASKEHAIFKQTDADVTSFDGGYGSAYLAKMVGQKKAREIFFLGRNYSA 193 Query: 201 QDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEK 260 Q+A + G+V+K+ P L + A + A++I + S + M K ++N + + + Sbjct: 194 QEAFEMGMVNKVVPHAELEDTAYEWAQEILAKSPTSIRMLKFAMNLTDDGMVGQQV-FAG 252 Query: 261 KLFYSTFATDDRKEGMTAFVEKRKANFKD 289 + + TD+ KEG AF+EKRK +F + Sbjct: 253 EATRLAYMTDEAKEGRNAFLEKRKPDFGE 281 >2PPY-A nrPDB Length = 265 Score = 244 bits (624), Expect = 3e-65, Method: Composition-based stats. Identities = 78/251 (31%), Positives = 136/251 (54%), Gaps = 5/251 (1%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAI-VLTGGDKAFAAGADIK 101 K + + I L N+ E N A+ DP + + V++ K F+AGADI Sbjct: 15 KEDGIAEIHL-HINKSNSYDLEFYKEFNAAIDDIRFDPDIKVVIVMSDVPKFFSAGADIN 73 Query: 102 EMQNL--SFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKA- 158 +++ F+ + + D + + + IA + G+ GGG E+A+ CD+ + G++A Sbjct: 74 FLRSADPRFKTQFCLFCNETLDKIARSPQVYIACLEGHTVGGGLEMALACDLRFMGDEAG 133 Query: 159 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETL 218 + PE+ +G + G GGTQRL R +G S A++M +TG+ I+ Q+A + GLV+++ P Sbjct: 134 KIGLPEVSLGVLAGTGGTQRLARLIGYSRALDMNITGETITPQEALEIGLVNRVFPQAET 193 Query: 219 VEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTA 278 E + A K+A+++ V+ K ++ EM L + E +L F ++D KEG++A Sbjct: 194 RERTREYARKLANSATYAVSNIKLAIMNGKEMPLNVAIRYEGELQNLLFRSEDAKEGLSA 253 Query: 279 FVEKRKANFKD 289 F+EKR+ N+K Sbjct: 254 FLEKRQPNWKG 264 >1EF9-A nrPDB Length = 261 Score = 240 bits (612), Expect = 6e-64, Method: Composition-based stats. Identities = 75/251 (29%), Positives = 121/251 (48%), Gaps = 6/251 (2%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLT--GGDKAFAAGADIKE 102 N V +I+ N + LNAL ID+L QAL P + I+L G K F+AG DI E Sbjct: 12 NKVAVIEFNYGRKLNALSKVFIDDLMQALSDLNR-PEIRCIILRAPSGSKVFSAGHDIHE 70 Query: 103 MQNLSFQD-CYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFA 161 + + Y + + + KP+I+ V G +GG E+ M D+I A + F+ Sbjct: 71 LPSGGRDPLSYDDPLRQITRMIQKFPKPIISMVEGSVWGGAFEMIMSSDLIIAASTSTFS 130 Query: 162 QPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEE 221 + +G G LTR G + E++ T I+AQ A G+++ + VE L + Sbjct: 131 MTPVNLGVPYNLVGIHNLTRDAGFHIVKELIFTASPITAQRALAVGILNHVVEVEELEDF 190 Query: 222 AIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEK--KLFYSTFATDDRKEGMTAF 279 +Q A I+ + + +A+ KE + E + E+ + + + ++D +EGM AF Sbjct: 191 TLQMAHHISEKAPLAIAVIKEELRVLGEAHTMNSDEFERIQGMRRAVYDSEDYQEGMNAF 250 Query: 280 VEKRKANFKDQ 290 +EKRK NF Sbjct: 251 LEKRKPNFVGH 261 >5VE2-A nrPDB Length = 275 Score = 235 bits (599), Expect = 2e-62, Method: Composition-based stats. Identities = 73/244 (29%), Positives = 129/244 (52%), Gaps = 1/244 (0%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM 103 NN V + +NRP+ NAL L L L+ D + A++LT F AG D+ + Sbjct: 32 NNRVLSLTINRPELKNALNRELYAALADELERSNHDDQIRAVLLTANGDTFTAGNDLDDF 91 Query: 104 QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQP 163 N ++ + ++ +++ + P++ AVNG A G G + + CD++YA + A+F P Sbjct: 92 INP-VEESGTPSVIRFLKAISECETPIVVAVNGPAIGVGLTMLLHCDMVYASKSARFRAP 150 Query: 164 EILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAI 223 +G +P A + L AVG++ A +++L G + A++A AGLV+++ + LV E++ Sbjct: 151 FTHVGLVPEAASSLLLPLAVGQAWANDLMLAGRILDAREALSAGLVTRVFEDDVLVAESL 210 Query: 224 QCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKR 283 + AE++AS + V +K + + + K E +F A+ + KE + AF EKR Sbjct: 211 KIAEQVASLAPNSVKQSKRLIRGVNKEEVQAQMKREGVIFAEQLASAEFKESVAAFFEKR 270 Query: 284 KANF 287 +F Sbjct: 271 APHF 274 >5WYB-B nrPDB Length = 280 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 83/262 (31%), Positives = 129/262 (49%), Gaps = 4/262 (1%) Query: 31 ANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG- 89 ++F+ K+ LI +N P A N + L Q ++ D + A+V+TG Sbjct: 11 SSFDDTHKLTVEKHGHTALITINHPPA-NTWDRDSLIGLRQLIEHLNRDDDIYALVVTGQ 69 Query: 90 GDKAFAAGADIKEMQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAM 147 G K F+AGAD+ + + +F + ++ L + IAA+NGYA GGG E A+ Sbjct: 70 GPKFFSAGADLNMFADGDKARAREMARRFGEAFEALRDFRGVSIAAINGYAMGGGLECAL 129 Query: 148 MCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAG 207 CDI A +AQ A PE +G +P AGGTQ L VG+ A M+L +R+ A+ A + G Sbjct: 130 ACDIRIAERQAQMALPEAAVGLLPCAGGTQALPWLVGEGWAKRMILCNERVDAETALRIG 189 Query: 208 LVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTF 267 LV ++ A+ A K+A S + + K + A E E++ F F Sbjct: 190 LVEQVVDSGEARGAALLLAAKVARQSPVAIRTIKPLIQGARERAPNTWLPEERERFVDLF 249 Query: 268 ATDDRKEGMTAFVEKRKANFKD 289 D +EG+ AF+EKR +++ Sbjct: 250 DAQDTREGVNAFLEKRDPKWRN 271 >5JBW-A nrPDB Length = 260 Score = 228 bits (581), Expect = 2e-60, Method: Composition-based stats. Identities = 83/254 (32%), Positives = 131/254 (51%), Gaps = 3/254 (1%) Query: 40 KRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGD-KAFAAGA 98 K + + ++ NA+ ++ EL + + V A+V+TG KAF AGA Sbjct: 7 KVDARGPIEIWTIDGESRRNAISRAMLKELGELVTRVSSSRDVRAVVITGAGDKAFCAGA 66 Query: 99 DIKEMQNLSFQD--CYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 D+KE ++ + + + + + + IAA+NG A GGG ELA+ CD+ A Sbjct: 67 DLKERATMAEDEVRAFLDGLRRTFRAIEKSDCVFIAAINGAALGGGTELALACDLRVAAP 126 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 A+ E+ +G IPG GGTQRL R VG A +++LT RI+A +A GL +++ P Sbjct: 127 AAELGLTEVKLGIIPGGGGTQRLARLVGPGRAKDLILTARRINAAEAFSVGLANRLAPEG 186 Query: 217 TLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGM 276 L+ A AE + N+ I VA AK +++ + L + LE + + T+DR EG+ Sbjct: 187 HLLAVAYGLAESVVENAPIAVATAKHAIDEGTGLELDDALALELRKYEEILKTEDRLEGL 246 Query: 277 TAFVEKRKANFKDQ 290 AF EKR +K + Sbjct: 247 RAFAEKRAPVYKGR 260 >4JCS-A nrPDB Length = 286 Score = 224 bits (570), Expect = 4e-59, Method: Composition-based stats. Identities = 65/250 (26%), Positives = 120/250 (48%), Gaps = 5/250 (2%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQ 104 N VG I++NR N L +L L+ +D + +VLT +F AG ++ ++ Sbjct: 32 NNVGWIRMNRAAKHNPFDAELRADLMTVLERVRDDADIRVLVLTSHPGSFCAGGNLHVLR 91 Query: 105 -----NLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 ++ L+ + + +PVIAAV+G AFG G L++ DI+ A +A+ Sbjct: 92 DNLDSGPAYWQQRIKTGLRFIHDMLNLGRPVIAAVDGPAFGAGFALSLTADIVLASPRAR 151 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 F+ + +G +P G L RAVG A E++ + + A++A + GLV ++ E L Sbjct: 152 FSMAYLRLGLVPDLGALYLLPRAVGLQRAKELMFSTRELDAEEAHRLGLVMEVHESEALE 211 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 + A + AE + + +A+ K ++N + + LE + F+T + + + A Sbjct: 212 QRAREIAESLVQAAPTALALTKAALNVSLDSDEQTMFSLEAASQAAAFSTKEPRAAIEAL 271 Query: 280 VEKRKANFKD 289 + K+ F+ Sbjct: 272 LSKQPPPFRG 281 >4FZW-C nrPDB Length = 274 Score = 223 bits (568), Expect = 8e-59, Method: Composition-based stats. Identities = 78/255 (30%), Positives = 125/255 (49%), Gaps = 6/255 (2%) Query: 42 GKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK 101 V + LNRP+ LN+ D + +L + LK E D + ++LTG + F AG D+ Sbjct: 20 HVEKGVMTLTLNRPERLNSFNDEMHAQLAECLKQVERDDTIRCLLLTGAGRGFCAGQDLN 79 Query: 102 EM------QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG 155 + + L ++ KPVI AVNG A G G LA+ DI+ A Sbjct: 80 DRNVDPTGPAPDLGMSVERFYNPLVRRLAKLPKPVICAVNGVAAGAGATLALGGDIVIAA 139 Query: 156 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV 215 A+F +G IP GGT L R G++ AM + L G+++SA+ A + G++ ++ Sbjct: 140 RSAKFVMAFSKLGLIPDCGGTWLLPRVAGRARAMGLALLGNQLSAEQAHEWGMIWQVVDD 199 Query: 216 ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEG 275 ETL + A Q A +A+ + + K+++N+A TL LE+ + D +EG Sbjct: 200 ETLADTAQQLARHLATQPTFGLGLIKQAINSAETNTLDTQLDLERDYQRLAGRSADYREG 259 Query: 276 MTAFVEKRKANFKDQ 290 ++AF+ KR F + Sbjct: 260 VSAFLAKRSPQFTGK 274 >4JWV-A nrPDB Length = 278 Score = 222 bits (567), Expect = 1e-58, Method: Composition-based stats. Identities = 86/265 (32%), Positives = 130/265 (49%), Gaps = 7/265 (2%) Query: 27 FASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIV 86 F S A+ ++ I V ++LNRP+ LNA+ + D L A + + A+V Sbjct: 20 FQSMADIDFRI------EGHVAHVRLNRPQGLNAITQEMDDLLLDAWTEVNANSDIWAVV 73 Query: 87 LTG-GDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCEL 145 L+ G+KAF GAD+ + L KKP++AAV G+ GGG EL Sbjct: 74 LSAEGEKAFCIGADVSGGAERKTRMALGGGLTGIGGPLVTCKKPMVAAVQGFCVGGGFEL 133 Query: 146 AMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 AM DII A + AQF PE +G I G R R + +A++++LTG+RI A +A+ Sbjct: 134 AMCADIIVAADTAQFGLPETKVGIIGECGVVHRAMRQLPYHIALQLILTGERIKADEARH 193 Query: 206 AGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYS 265 GLV+++ P L E A++ A K+ + S + V AK + L + Sbjct: 194 YGLVNEVVPFAELEEAALRWASKLNAASPLAVQAAKAAALGRLGHPLEVALMTRFEPIEE 253 Query: 266 TFATDDRKEGMTAFVEKRKANFKDQ 290 AT+D+KEG A E+RK + + Sbjct: 254 YAATEDKKEGERAAGERRKPVWTGK 278 >2VSU-C nrPDB Length = 275 Score = 221 bits (562), Expect = 4e-58, Method: Composition-based stats. Identities = 73/250 (29%), Positives = 117/250 (46%), Gaps = 9/250 (3%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE- 102 + + + LNRP+ NA+ L E+ L+T E+DPA G +VLTG +A+ AG D+KE Sbjct: 16 EDGIAFVILNRPEKRNAMSPTLNREMIDVLETLEQDPAAGVLVLTGAGEAWTAGMDLKEY 75 Query: 103 -MQNLSFQDCYSSKFLK-----HWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 + + + K + W L KP IA VNG+ FGGG + CD+ + Sbjct: 76 FREVDAGPEILQEKIRREASQWQWKLLRMYAKPTIAMVNGWCFGGGFAPLVACDLAICAD 135 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 +A F EI G PG ++ + VG ++ ++TG Q A + GLV++ P+ Sbjct: 136 EATFGLSEINWGIPPGNLVSKAMADTVGHRQSLYYIMTGKTFGGQKAAEMGLVNESVPLA 195 Query: 217 TLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSK--LEKKLFYSTFATDDRKE 274 L E I+ A + + +V+ AK E+T + K T R++ Sbjct: 196 QLREVTIELARNLLEKNPVVLRAAKHGFKRCRELTWEQNEDYLYAKLDQSRLLDTGGREQ 255 Query: 275 GMTAFVEKRK 284 GM F++ + Sbjct: 256 GMKQFLDDKS 265 >5YLO-A nrPDB Length = 271 Score = 220 bits (561), Expect = 6e-58, Method: Composition-based stats. Identities = 76/250 (30%), Positives = 111/250 (44%), Gaps = 5/250 (2%) Query: 46 TVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQN 105 + + LNRP+ NAL ++ L+ L E DPAV A+VL G ++F AGAD+ E Sbjct: 14 GIAWLVLNRPQQRNALDIPTLEALHVRLDACERDPAVRAVVLGGSGRSFCAGADLAEWAA 73 Query: 106 LSFQDCYSSKFLK-----HWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQF 160 + S L + KP +AAVNG A G G +LA+ CD A A+F Sbjct: 74 AEARGELESYGWTEAAHALMGRLHALDKPTVAAVNGSAVGAGMDLALCCDFRIAAASARF 133 Query: 161 AQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVE 220 + P AG + L R +G A ++ + SA+ A AGLV ++ E LVE Sbjct: 134 KAGYTGMAYCPDAGASWHLPRLLGSEAAKRLLFLDEAWSAERALGAGLVGEVVADEHLVE 193 Query: 221 EAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFV 280 A ++AS A K + +L E + E+ ++D E + A Sbjct: 194 AVGAFAARLASGPTFAFAQTKRLLRDGAGRSLAEQLRAEQAAGLLCGRSEDAAEALRAVA 253 Query: 281 EKRKANFKDQ 290 EKR F + Sbjct: 254 EKRSPQFSGR 263 >4JFC-A nrPDB Length = 281 Score = 216 bits (550), Expect = 9e-57, Method: Composition-based stats. Identities = 74/254 (29%), Positives = 121/254 (47%), Gaps = 5/254 (1%) Query: 40 KRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGAD 99 K ++ L+ P+ NAL + +AL E +P + ++V+TG F AG + Sbjct: 28 KSTSEGQTLILTLSNPEFRNALGPEIYAAGIEALNAAENNPEIRSVVITGEGAVFCAGGN 87 Query: 100 IKEMQNLS-----FQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA 154 ++ +Q Q D + KPVIAAV G A G G LA+ CD + A Sbjct: 88 LQRLQANRREAPEVQAQSIEGLHNWIDSIRTYPKPVIAAVEGAAAGAGFSLALACDFVVA 147 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICP 214 A F +G P GG+ L R++ ++LA E+++ G+RISAQ GLV+K+ Sbjct: 148 ASNAVFVMSYSTVGLSPDGGGSWSLARSLPRALASELLMGGERISAQRLHDLGLVNKVAS 207 Query: 215 VETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKE 274 + EA++ A ++ + + +A KE +N A TL++ E+ F + E Sbjct: 208 AGDALSEALRMAGQLNARAPNALASIKELINEASSNTLSQQLACERDHFVRNLHHSNGGE 267 Query: 275 GMTAFVEKRKANFK 288 G+ AF+ KR ++ Sbjct: 268 GIAAFLGKRTPQYR 281 >1NZY-B nrPDB Length = 269 Score = 213 bits (542), Expect = 8e-56, Method: Composition-based stats. Identities = 71/251 (28%), Positives = 124/251 (49%), Gaps = 7/251 (2%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 + V I + P+ NAL + E+ AL EED +VGA+++TG + AF AG ++E Sbjct: 9 VEDGVAEITIKLPRHRNALSVKAMQEVTDALNRAEEDDSVGAVMITGAEDAFCAGFYLRE 68 Query: 103 MQ----NLSFQDCYSSKFLKHWD---HLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG 155 + +D + L + +VK+PV+AA+NG A GGG +++ D+ Sbjct: 69 IPLDKGVAGVRDHFRIAALWWHQMIHKIIRVKRPVLAAINGVAAGGGLGISLASDMAICA 128 Query: 156 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV 215 + A+F IG + L R VG AME++LT + ++AK GLVS++ P Sbjct: 129 DSAKFVCAWHTIGIGNDTATSYSLARIVGMRRAMELMLTDRTLYPEEAKDWGLVSRVYPK 188 Query: 216 ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEG 275 + E A + A ++A+ + MAKE +A + + E ++ E + ++ Sbjct: 189 DEFREVAWKVARELAAAPTHLQVMAKERFHAGWMQPVEECTEFEIQNVIASVTHPHFMPC 248 Query: 276 MTAFVEKRKAN 286 +T F++ +A+ Sbjct: 249 LTRFLDGHRAD 259 >3HIN-A nrPDB Length = 275 Score = 212 bits (541), Expect = 1e-55, Method: Composition-based stats. Identities = 71/264 (26%), Positives = 121/264 (45%), Gaps = 7/264 (2%) Query: 28 ASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVL 87 A+ A+ ++ + G V I LNRPK NAL DGL+ L L + A+V+ Sbjct: 10 ATIADPSTLVVDTVGP---VLTIGLNRPKKRNALNDGLMAALKDCLTDIP--DQIRAVVI 64 Query: 88 TGGDKAFAAGADIKEMQNLSFQDCY--SSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCEL 145 G F+AG D+ E++ + S + + +D + + PVIAA+ G GGG EL Sbjct: 65 HGIGDHFSAGLDLSELRERDATEGLVHSQTWHRVFDKIQYCRVPVIAALKGAVIGGGLEL 124 Query: 146 AMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQ 205 A I A A +A PE G G GG+ RL R +G + +M+LTG SA + Sbjct: 125 ACAAHIRVAEASAYYALPEGSRGIFVGGGGSVRLPRLIGVARMADMMLTGRVYSAAEGVV 184 Query: 206 AGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYS 265 G + + ++A++ ++A N+ + +++ E G +E + Sbjct: 185 HGFSQYLIENGSAYDKALELGNRVAQNAPLTNFAVLQALPMIAEANPQTGLLMESLMATV 244 Query: 266 TFATDDRKEGMTAFVEKRKANFKD 289 + + K + AF++ + A ++ Sbjct: 245 AQSDQEAKTRIRAFLDHKTAKVRE 268 >3I47-A nrPDB Length = 268 Score = 211 bits (537), Expect = 3e-55, Method: Composition-based stats. Identities = 76/254 (29%), Positives = 122/254 (48%), Gaps = 11/254 (4%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM 103 + VGL+ +NR NA + L+ E+ L + D V IVL K F+AGAD+ M Sbjct: 11 QDKVGLLTMNRISKHNAFDNQLLTEMRIRLDSAINDTNVRVIVLKANGKHFSAGADLTWM 70 Query: 104 QNL-------SFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 Q++ + +D L + ++Q KP IA V G AFGGG LA CDI A Sbjct: 71 QSMANFTEEENLEDSLVLGNLMY--SISQSPKPTIAMVQGAAFGGGAGLAAACDIAIAST 128 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 A+F E+ +G IP A + + RA+G+ A + ++ + A A LV P + Sbjct: 129 SARFCFSEVKLGLIP-AVISPYVVRAIGERAAKMLFMSAEVFDATRAYSLNLVQHCVPDD 187 Query: 217 TLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGS-KLEKKLFYSTFATDDRKEG 275 TL+E ++ A +I++N+ V +K+ + E + L +D+ +EG Sbjct: 188 TLLEFTLKYASQISNNAPEAVKNSKQLAQYVANKKIDEELVRYTASLIAHKRVSDEGQEG 247 Query: 276 MTAFVEKRKANFKD 289 + AF+ K N+ + Sbjct: 248 LKAFLNKEIPNWNE 261 >3OME-A nrPDB Length = 282 Score = 209 bits (531), Expect = 2e-54, Method: Composition-based stats. Identities = 65/218 (29%), Positives = 107/218 (49%), Gaps = 9/218 (4%) Query: 41 RGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADI 100 G +++ I LNRP+A NA L+DEL+ A ED V I+L K F+AG D+ Sbjct: 27 YGVADSIATITLNRPEAANAQNPELLDELDAAWTRAAEDNEVKVIILRANGKHFSAGHDL 86 Query: 101 KEMQNLSFQ-------DCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIY 153 + + + + ++L + V KP IAAV G GG L CD+I Sbjct: 87 RGGGEVPEKISLEFIIQHEARRYLDYTLRWRNVPKPSIAAVQGRCISGGLLLCWPCDLIL 146 Query: 154 AGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIC 213 A + A F+ P L+G G T +G A E++ TG ++A++A++ G+V+++ Sbjct: 147 ASDDALFSDPVALMGI--GGVEYHGHTWELGPRKAKEILFTGRALTAEEAERTGMVNRVV 204 Query: 214 PVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMT 251 + L + + AE+IA+ + AK +VN ++ Sbjct: 205 ARDELDAQTRELAEQIATMPPFALRQAKRAVNQTLDVQ 242 >2A81-A nrPDB Length = 250 Score = 207 bits (526), Expect = 5e-54, Method: Composition-based stats. Identities = 63/237 (26%), Positives = 102/237 (43%), Gaps = 5/237 (2%) Query: 41 RGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAFAAGAD 99 ++ V +I L+ P N L + AL D +V A+V+ GG +++F+AG D Sbjct: 4 EENSDEVRVITLDHPNKHNPFSRTLETSVKDALARANADDSVRAVVVYGGAERSFSAGGD 63 Query: 100 IKEMQNLSFQD---CYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 E++ LS + + + + + + V KP IAAV+GYA G G + A+M D Sbjct: 64 FNEVKQLSRSEDIEEWIDRVIDLYQAVLNVNKPTIAAVDGYAIGMGFQFALMFDQRLMAS 123 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 A F PE+ G + G L G S E++ + A LV+++ Sbjct: 124 TANFVMPELKHGI-GCSVGAAILGFTHGFSTMQEIIYQCQSLDAPRCVDYRLVNQVVESS 182 Query: 217 TLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRK 273 L++ AI A +AS K +VN F L + K + + F D + Sbjct: 183 ALLDAAITQAHVMASYPASAFINTKRAVNKPFIHLLEQTRDASKAVHKAAFQARDAQ 239 >3HE2-A nrPDB Length = 264 Score = 205 bits (523), Expect = 1e-53, Method: Composition-based stats. Identities = 74/243 (30%), Positives = 116/243 (47%), Gaps = 10/243 (4%) Query: 47 VGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNL 106 V I+L RP+ NAL L++EL QA++ D + AIVLTG AF AGAD+ Sbjct: 31 VLTIELQRPERRNALNSQLVEELTQAIRKA-GDGSARAIVLTGQGTAFCAGADLS---GD 86 Query: 107 SFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEIL 166 +F Y + ++ + PV+ A+NG A G G +LAM CD+ A F P Sbjct: 87 AFAADYPDRLIELHKAMDASPMPVVGAINGPAIGAGLQLAMQCDLRVVAPDAFFQFPTSK 146 Query: 167 IGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCA 226 G +RL+ VG A M+L+ ++++A+ A G+ ++I + A A Sbjct: 147 YGLALDNWSIRRLSSLVGHGRARAMLLSAEKLTAEIALHTGMANRIGTLAD----AQAWA 202 Query: 227 EKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKAN 286 +IA + + + AK +N + + E K+LF + + D E A +EKR Sbjct: 203 AEIARLAPLAIQHAKRVLND--DGAIEEAWPAHKELFDKAWGSQDVIEAQVARMEKRPPK 260 Query: 287 FKD 289 F+ Sbjct: 261 FQG 263 >5KJP-A nrPDB Length = 265 Score = 201 bits (511), Expect = 3e-52, Method: Composition-based stats. Identities = 84/268 (31%), Positives = 131/268 (48%), Gaps = 7/268 (2%) Query: 23 AWRPFASGANFE-YIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPA 81 A + AN E ++ E+R + + +I +NRPKA NA+ + L A+ + D Sbjct: 3 AMSSESDAANTEPEVLVEQR---DRILIITINRPKAKNAVNAAVSRGLADAMDQLDGDAG 59 Query: 82 VGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGG 141 + +LTGG +F AG D+K + + KP+IAAV GYA G Sbjct: 60 LSVAILTGGGGSFCAGMDLKAFARG---ENVVVEGRGLGFTERPPTKPLIAAVEGYALAG 116 Query: 142 GCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQ 201 G ELA+ D+I A + F PE+ G + G GG RL + ++AME+ LTGD + A+ Sbjct: 117 GTELALAADLIVAARDSAFGIPEVKRGLVAGGGGLLRLPERIPYAIAMELALTGDNLPAE 176 Query: 202 DAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKK 261 A + GLV+ + T ++ AI AEKI +N + V K + + + + K Sbjct: 177 RAHELGLVNVLAEPGTALDAAIALAEKITANGPLAVVATKRIITESRGWSPDTMFAEQMK 236 Query: 262 LFYSTFATDDRKEGMTAFVEKRKANFKD 289 + F ++D KEG AF E+R+ + Sbjct: 237 ILVPVFTSNDAKEGAIAFAERRRPRWTG 264 >1XX4-A nrPDB Length = 261 Score = 200 bits (509), Expect = 5e-52, Method: Composition-based stats. Identities = 54/254 (21%), Positives = 108/254 (42%), Gaps = 7/254 (2%) Query: 36 IIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG-DKAF 94 ++ EK G+ + +++ P +N+L + E +L+ E D ++ ++LT F Sbjct: 6 VLVEKEGEA-GIAVMKFKNP-PVNSLSLEFLTEFVISLEKLENDKSIRGVILTSERPGIF 63 Query: 95 AAGADIKEM--QNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDII 152 +AG D+ EM +N + Y + W L +I+A+NG + GGC +A+ CD Sbjct: 64 SAGLDLMEMYGRNPAHYAEYWKAVQELWLRLYLSNLTLISAINGASPAGGCLMALTCDYR 123 Query: 153 YAGEKAQ--FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVS 210 + ++ E L+G + +G A + G +A + GLV Sbjct: 124 IMADNSKYTIGLNESLLGIVAPFWLKDNYVNTIGHRAAERALQLGTLFPPAEALKVGLVD 183 Query: 211 KICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATD 270 ++ P + + +A K + + K + A L + + + + F S + D Sbjct: 184 EVVPEDQVHSKARSVMAKWFTIPDHSRQLTKSMMRKATADNLIKQREADIQNFTSFISRD 243 Query: 271 DRKEGMTAFVEKRK 284 ++ + ++EK K Sbjct: 244 SIQKSLHVYLEKLK 257 >4IZC-A nrPDB Length = 275 Score = 194 bits (493), Expect = 4e-50, Method: Composition-based stats. Identities = 70/250 (28%), Positives = 111/250 (44%), Gaps = 6/250 (2%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 ++N V ++ LNRP NAL I+EL T V A+VLTG F AG D+ E Sbjct: 17 RDNGVCVVTLNRPDKRNALDVATIEELVTFFSTAHR-KGVRAVVLTGAGDHFCAGLDLVE 75 Query: 103 MQNLSF-QDCYSSKFLKHWDHLTQVKK---PVIAAVNGYAFGGGCELAMMCDIIYAGEKA 158 D + L+ + +++ P+IAA+ G GGG LA + + Sbjct: 76 HWKADRSADDFMHVCLRWHEAFNKMEYGGVPIIAALRGAVVGGGLALASAAHLRVMDQST 135 Query: 159 QFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETL 218 FA PE G G G T R++ +GK ++M+LTG Q+A GL I + Sbjct: 136 YFALPEGQRGIFTGGGATIRVSDMIGKYRMIDMILTGRVYQGQEAADLGLAQYITEGSSF 195 Query: 219 VEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTA 278 ++A++ A+KIASN + +++ M+ + + E + +E + A Sbjct: 196 -DKAMELADKIASNLPLTNFAICSAISHMQNMSGLDAAYAEAFVGGIVNTQPAARERLEA 254 Query: 279 FVEKRKANFK 288 F K A + Sbjct: 255 FANKTAARVR 264 >3LAO-A nrPDB Length = 258 Score = 185 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 64/244 (26%), Positives = 106/244 (43%), Gaps = 3/244 (1%) Query: 40 KRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGAD 99 R + + LI L+R NA ++ +L A+ +E VL + F AG D Sbjct: 15 TREQRGHLFLIGLDRAGKRNAFDSAMLADLALAMGEYERSEESRCAVLFAHGEHFTAGLD 74 Query: 100 IKEMQNLSFQDC--YSSKFLKHWDHLT-QVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 + E+ Y + W + + KP++ AV G + G EL + DI A Sbjct: 75 LMELAPKLAASGFRYPDGGVDPWGVVQPRRSKPLVVAVQGTCWTAGIELMLNADIAVAAR 134 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 +FA E+L G P G T R RA G + AM +LTGD A +A + L++++ Sbjct: 135 GTRFAHLEVLRGIPPLGGSTVRFPRAAGWTDAMRYILTGDEFDADEALRMRLLTEVVEPG 194 Query: 217 TLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGM 276 + A++ AE+IA + + V A +S + + + ++D +EG+ Sbjct: 195 EELARALEYAERIARAAPLAVRAALQSAFQGRDEGDDAALSRVNESLAALIGSEDVREGV 254 Query: 277 TAFV 280 A V Sbjct: 255 LAMV 258 >4ZU2-A nrPDB Length = 272 Score = 185 bits (470), Expect = 2e-47, Method: Composition-based stats. Identities = 69/248 (27%), Positives = 106/248 (42%), Gaps = 7/248 (2%) Query: 46 TVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQN 105 V I LNRP++ NA+ ++ EL L +D +V A+VL G D F AG DIK+M Sbjct: 16 GVLRITLNRPQSRNAMSLAMVGELRAVLAAVRDDRSVRALVLRGADGHFCAGGDIKDMAG 75 Query: 106 LSFQ-----DCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQF 160 + F + + ++A V G GGG LA + D+ A AQF Sbjct: 76 ARAAGAEAYRTLNRAFGSLLEEAQAAPQLLVALVEGAVLGGGFGLACVSDVAIAAADAQF 135 Query: 161 AQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI-CPVETLV 219 PE +G +P A + R +G + A + LT R ++A + GLV + L Sbjct: 136 GLPETSLGILP-AQIAPFVVRRIGLTQARRLALTAARFDGREALRLGLVHFCEADADALE 194 Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 + + E++ + A K + A+ L + F + EG AF Sbjct: 195 QRLEETLEQLRRCAPNANAATKALLLASESGELGALLDDAARQFAEAVGGAEGSEGTLAF 254 Query: 280 VEKRKANF 287 V+KRK + Sbjct: 255 VQKRKPVW 262 >6IUM-B nrPDB Length = 701 Score = 183 bits (464), Expect = 9e-47, Method: Composition-based stats. Identities = 77/281 (27%), Positives = 121/281 (43%), Gaps = 36/281 (12%) Query: 37 IAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAA 96 + + + V +I L+ P +N L + + + +D AV AIV+TG KAF+ Sbjct: 1 MTAQYQVQDGVAVITLDNP-PVNGLGHSTRLGIVEGMTRALDDAAVKAIVITGAGKAFSG 59 Query: 97 GADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 GADI+E + L KPV+AAV+ A GGG ELA+ C+ A + Sbjct: 60 GADIREFNT--PKAMQEPTLHSVIRVLEGSSKPVVAAVHSVAMGGGLELALGCNYRVASK 117 Query: 157 KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVE 216 AQ A PE+ +G +PGAGGTQRL R +G A M+++G + ++ L +I + Sbjct: 118 GAQIALPEVKLGLLPGAGGTQRLPRVIGLEAAANMIVSGTPVLSEKFAGTKLFDEIVDGD 177 Query: 217 TLVEEAIQCAEKI--ASNSKIVVAMAK-----------------ESVNAAFEMTL----- 252 L A++ A+ + A+ V K ++ F L Sbjct: 178 VL-PAAVKFAQNVGAATGPHPKVRDLKVRHENPEGYLGFARNTVAAMAKNFPAPLKCLEA 236 Query: 253 --------TEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKA 285 +G K E++ F T + + AF +R A Sbjct: 237 VAGSLKPFEQGLKQEREGFLYLVTTPESRALRHAFFGERAA 277 >3ZWA-A nrPDB Length = 742 Score = 182 bits (463), Expect = 1e-46, Method: Composition-based stats. Identities = 82/276 (29%), Positives = 129/276 (46%), Gaps = 40/276 (14%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQ 104 +++ +I+L P +NA+ +I E+ L+ D V AIV+ G + F AGADI Sbjct: 29 HSLAMIRLCNP-PVNAVSPTVIREVRNGLQKAGSDHTVKAIVICGANGNFCAGADIHGFS 87 Query: 105 NLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPE 164 + S D + + +KPV+AA+ G A GGG ELA+ C A KA+ PE Sbjct: 88 AFTPGLALGSLV----DEIQRYQKPVLAAIQGVALGGGLELALGCHYRIANAKARVGLPE 143 Query: 165 ILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQ 224 + +G +PGA GTQ L R VG +A++++ +G +SA +A + G++ + + + EEAI+ Sbjct: 144 VTLGILPGARGTQLLPRVVGVPVALDLITSGKYLSADEALRLGILDAVVKSDPV-EEAIK 202 Query: 225 CAEKIASNS-------------------KIVVAMAK---------------ESVNAAFEM 250 A+KI A+AK S+ A+ + Sbjct: 203 FAQKIIDKPIEPRRIFNKPVPSLPNMDSVFAEAIAKVRKQYPGVLAPETCVRSIQASVKH 262 Query: 251 TLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKAN 286 G K E+KLF A+ K AF ++ AN Sbjct: 263 PYEVGIKEEEKLFMYLRASGQAKALQYAFFAEKSAN 298 >3BPT-A nrPDB Length = 363 Score = 178 bits (451), Expect = 3e-45, Method: Composition-based stats. Identities = 74/243 (30%), Positives = 110/243 (45%), Gaps = 14/243 (5%) Query: 42 GKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADI 100 GK G+I LNRPK LNAL +I ++ LK +E+DP I++ G G KAF AG DI Sbjct: 11 GKKGCTGVITLNRPKFLNALTLNMIRQIYPQLKKWEQDPETFLIIIKGAGGKAFCAGGDI 70 Query: 101 KEMQNL--SFQDCYSSKFLKHW---DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG 155 + + + Q F + + + + +KP +A ++G GGG L++ A Sbjct: 71 RVISEAEKAKQKIAPVFFREEYMLNNAVGSCQKPYVALIHGITMGGGVGLSVHGQFRVAT 130 Query: 156 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV 215 EK FA PE IG P GG L R GK L + LTG R+ +D +AG+ + Sbjct: 131 EKCLFAMPETAIGLFPDVGGGYFLPRLQGK-LGYFLALTGFRLKGRDVYRAGIATHFVDS 189 Query: 216 ETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEG----SKLEKKLFYSTFATDD 271 E L A+ + +A S +A N E + + S F+ + Sbjct: 190 EKL---AMLEEDLLALKSPSKENIASVLENYHTESKIDRDKSFILEEHMDKINSCFSANT 246 Query: 272 RKE 274 +E Sbjct: 247 VEE 249 Score = 44.2 bits (103), Expect = 6e-05, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 27/71 (38%), Gaps = 2/71 (2%) Query: 220 EEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 A++ + I S + + + TL E +E +L + D EG+ A Sbjct: 260 SFALEQLKVINKMSPTSLKITLRQLMEGSSKTLQEVLTMEYRLSQACMRGHDFHEGVRAV 319 Query: 280 V--EKRKANFK 288 + + + +K Sbjct: 320 LIDKDQSPKWK 330 >5ZRV-A nrPDB Length = 763 Score = 176 bits (447), Expect = 8e-45, Method: Composition-based stats. Identities = 68/228 (29%), Positives = 104/228 (45%), Gaps = 20/228 (8%) Query: 25 RPFASGANFEYIIAEKRGKNNTVGLIQLNRPK-ALNALCDGLIDELNQALKTFEEDPAVG 83 R F + G V ++++N P +N L L E ++ + + Sbjct: 27 RNFTGSSALLTRTHINYGVKGDVAVVRINSPNSKVNTLSKELHSEFSEVMNEIWASDQIR 86 Query: 84 -AIVLTGGDKAFAAGADIKEMQ---NLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAF 139 A++++ F AGADI + L S + + + L + KP++AA+NG Sbjct: 87 SAVLISSKPGCFIAGADINMLAACKTLQEVTQLSQEAQRIVEKLEKSTKPIVAAINGSCL 146 Query: 140 GGGCELAMMCDIIYAG--EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDR 197 GGG E+A+ C A K PE+L+G +PGAGGTQRL + VG A++M+LTG Sbjct: 147 GGGLEVAISCQYRIATKDRKTVLGTPEVLLGALPGAGGTQRLPKMVGVPAALDMMLTGRS 206 Query: 198 ISAQDAKQAGLVSKICPV-------------ETLVEEAIQCAEKIASN 232 I A AK+ GLV ++ E L E AI A+ +A Sbjct: 207 IRADRAKKMGLVDQLVEPLGPGLKPPEERTIEYLEEVAITFAKGLADK 254 >4Q1J-A nrPDB Length = 268 Score = 176 bits (446), Expect = 1e-44, Method: Composition-based stats. Identities = 59/260 (22%), Positives = 111/260 (42%), Gaps = 13/260 (5%) Query: 19 VRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEE 78 + P E I + + ++ T NA L D+L QA + + Sbjct: 16 FQGPMTHSVVELIEIESAIIQVKMQDRT----------HKNAFSQELTDDLIQAFEYIRQ 65 Query: 79 DPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLT-QVKKPVIAAVNGY 137 +P A++LTG D FA+G + + L Q + + L + PVIAA+ G+ Sbjct: 66 NPKYKAVILTGYDNYFASGGTQEGL--LRIQQGLTKFTDDNLYSLALDCEIPVIAAMQGH 123 Query: 138 AFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDR 197 GGG + + DI+ ++ + + G PG G T + + +G SLA E++L Sbjct: 124 GIGGGFVMGLFADIVILSRESVYTANFMKYGFTPGMGATFIVPKKLGFSLAQEILLNAGS 183 Query: 198 ISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSK 257 D ++ G+ K+ P +++ A++ A+++A + + K+ + A L + Sbjct: 184 YRGADLEKRGVPFKVLPRAEVLDYAVELAQELAEKPRNSLVTLKDHLVAPLRDQLPRVIE 243 Query: 258 LEKKLFYSTFATDDRKEGMT 277 E + TF ++ K + Sbjct: 244 QELMMAEKTFHHEEVKSRIK 263 >5MRE-88 nrPDB Length = 457 Score = 165 bits (419), Expect = 1e-41, Method: Composition-based stats. Identities = 51/198 (25%), Positives = 85/198 (42%), Gaps = 13/198 (6%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG--DKAFAAGADI 100 +T +I LNRPK LNAL + + + + L + + ++L ++F AG D+ Sbjct: 8 VQDTARVITLNRPKKLNALNAEMSESMFKTLNEYAKSDTTNLVILKSSNRPRSFCAGGDV 67 Query: 101 KEMQNLSFQDCYSSKFLKHWD------HLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA 154 + +F ++ D + KP++ ++G GGG L++ A Sbjct: 68 ATVAIFNFNKEFAKSIKFFTDEYSLNFQIATYLKPIVTFMDGITMGGGVGLSIHTPFRIA 127 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAV-----GKSLAMEMVLTGDRISAQDAKQAGLV 209 E ++A PE+ IG P G T L R V +A+ + LTG+ ++ DA GL Sbjct: 128 TENTKWAMPEMDIGFFPDVGSTFALPRIVTLANSNSQMALYLCLTGEVVTGADAYMLGLA 187 Query: 210 SKICPVETLVEEAIQCAE 227 S E L + E Sbjct: 188 SHYVSSENLDALQKRLGE 205 >2WTB-A nrPDB Length = 725 Score = 165 bits (417), Expect = 2e-41, Method: Composition-based stats. Identities = 67/191 (35%), Positives = 96/191 (50%), Gaps = 6/191 (3%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIK--- 101 + V +I L P +N+L ++ L + V AIV+TG F+ G DI Sbjct: 16 DGVAVITLINP-PVNSLSFDVLYNLKSNYEEALSRNDVKAIVITGAKGRFSGGFDISGFG 74 Query: 102 EMQNLSFQDCYSSKFLKHW--DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQ 159 EMQ + ++ + D L +KP +AA++G A GGG ELAM C + AQ Sbjct: 75 EMQKGNVKEPKAGYISIDIITDLLEAARKPSVAAIDGLALGGGLELAMACHARISAPAAQ 134 Query: 160 FAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLV 219 PE+ +G IPG GGTQRL R VG + A+EM+LT + A++ GL+ + P LV Sbjct: 135 LGLPELQLGVIPGFGGTQRLPRLVGLTKALEMILTSKPVKAEEGHSLGLIDAVVPPAELV 194 Query: 220 EEAIQCAEKIA 230 A + A I Sbjct: 195 TTARRWALDIV 205 >4J2U-A nrPDB Length = 365 Score = 161 bits (407), Expect = 4e-40, Method: Composition-based stats. Identities = 74/306 (24%), Positives = 116/306 (37%), Gaps = 61/306 (19%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTG-GDKAFAAGADIK 101 K G I L+RP ALNAL ++ E++ AL+ + DP V +V+ G +AF AG DI Sbjct: 30 KVRRAGRITLSRPAALNALTCAMVQEIDAALRGWIGDPEVELVVIDAEGPRAFCAGGDIA 89 Query: 102 EMQNLS------FQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAG 155 E+ F + + D + KP+++ + G+ GGG L G Sbjct: 90 ELHGRGVAGDHAFGQDFWRVEYRMNDRIAAFPKPIVSLMQGFTMGGGVGLGCHARHRIVG 149 Query: 156 EKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPV 215 E +Q + PE IG +P GGT L RA G + + + LTG R+ DA AG + P Sbjct: 150 ETSQISMPECAIGLVPDVGGTHLLARAPG-RIGVWLGLTGARMGPGDAIFAGFADRFVPE 208 Query: 216 ET---------------------------LVEE-----------------------AIQC 225 L +E A + Sbjct: 209 ADWPDLIAALEGGDLALPDHAAPEGRLPVLQDEIDRLFAGTLAEIPARLEATDTPLAAEA 268 Query: 226 AEKIASNSKIVVAMAKESVNA-AFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFV--EK 282 + + +S + +A E + + E LE + Y D EG+ A + + Sbjct: 269 LKALRRSSPLALAATLEILQRLGPSAGIREALDLEYRFTYRAQGQADFLEGIRAAIIDKD 328 Query: 283 RKANFK 288 R ++ Sbjct: 329 RSPRWR 334 >4JSB-A nrPDB Length = 296 Score = 160 bits (404), Expect = 8e-40, Method: Composition-based stats. Identities = 64/261 (24%), Positives = 102/261 (39%), Gaps = 26/261 (9%) Query: 44 NNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM 103 + V I L+RP NA+ + EL + T + AV +V+TG F++G D+ Sbjct: 43 DGEVARITLSRPHRRNAMTGRMWTELARIGHTLPQ--AVRIVVITGEGPTFSSGIDLDMF 100 Query: 104 QNLSFQ-------------------DCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCE 144 Q D + + + + L + IAAV G+A G G + Sbjct: 101 QAGKVDGEPTPFTLLARDPNSTAALDQVIASYQEGFLWLRRADIVSIAAVRGHAIGAGFQ 160 Query: 145 LAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAK 204 LA+ CDI + AQ E +G +P GTQ L VG + A+E+ LT I A +A Sbjct: 161 LALSCDIRILSDTAQLCMKEPALGLVPDLTGTQPLVELVGVNRAIELCLTARTIDAAEAA 220 Query: 205 QAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFY 264 Q L ++ L ++ + KE + A L +++E+ Sbjct: 221 QLRLAERVVADAELDAAVDALVAQLLAVPAAAARATKELLLQAGRNDLATQARVERTAQL 280 Query: 265 STFATDDRKEGMTAFVEKRKA 285 + A E A R+ Sbjct: 281 ARLA-----ELAKASAAPRRP 296 >2D3T-A nrPDB Length = 715 Score = 158 bits (400), Expect = 3e-39, Method: Composition-based stats. Identities = 59/231 (25%), Positives = 99/231 (42%), Gaps = 26/231 (11%) Query: 54 RPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEM-QNLSFQDCY 112 + +++N ++EL QA+ + D +V ++++ G F GADI E +N D Sbjct: 25 KGESVNKFNRLTLNELRQAVDAIKADASVKGVIVSSGKDVFIVGADITEFVENFKLPDAE 84 Query: 113 ----SSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIG 168 + + K + + P +AA+NG A GGG E+ + D + A+ PE+ +G Sbjct: 85 LIAGNLEANKIFSDFEDLNVPTVAAINGIALGGGLEMCLAADFRVMADSAKIGLPEVKLG 144 Query: 169 TIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEK 228 PG GGT RL R +G A+E + +G A+DA + V + + L A+ Sbjct: 145 IYPGFGGTVRLPRLIGVDNAVEWIASGKENRAEDALKVSAVDAVVTADKLGAAALDL--- 201 Query: 229 IASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAF 279 K +++ + KLEK + E M AF Sbjct: 202 -----------IKRAISGELDYKAKRQPKLEKLKLNAI-------EQMMAF 234 >3HP0-A nrPDB Length = 267 Score = 152 bits (385), Expect = 1e-37, Method: Composition-based stats. Identities = 62/249 (24%), Positives = 98/249 (39%), Gaps = 9/249 (3%) Query: 46 TVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE--- 102 +V I +RP+A N + D LI+E Q L E V +VL G + F GAD +E Sbjct: 16 SVCYITFHRPEANNTINDTLIEECLQVLNQCETS-TVTVVVLEGLPEVFCFGADFQEIYQ 74 Query: 103 -MQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFA 161 M+ Q W L I+ V G GG DI A + A F+ Sbjct: 75 EMKRGRKQASSQEPLYDLWMKLQTGPYVTISHVRGKVNAGGLGFVSATDIAIADQTASFS 134 Query: 162 QPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEE 221 E+L G P A L R +G+ A M L IS Q+A + GL+ Sbjct: 135 LSELLFGLYP-ACVLPFLIRRIGRQKAHYMTLMTKPISVQEASEWGLIDAF--DAESDVL 191 Query: 222 AIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVE 281 + ++ +K +A K+ ++ + ++ F+ + G+ +VE Sbjct: 192 LRKHLLRLRRLNKKGIAHYKQ-FMSSLDHQVSRAKATALTANQDMFSDPQNQMGIIRYVE 250 Query: 282 KRKANFKDQ 290 + ++DQ Sbjct: 251 TGQFPWEDQ 259 >4HDT-A nrPDB Length = 353 Score = 148 bits (373), Expect = 3e-36, Method: Composition-based stats. Identities = 75/322 (23%), Positives = 131/322 (40%), Gaps = 68/322 (21%) Query: 31 ANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGG 90 A E ++ G VGL+ LNRPKA+N+L G++ + + L +E D +V A++LTG Sbjct: 6 AKNEDVLVNVEG---GVGLLTLNRPKAINSLTHGMVTTMAERLAAWENDDSVRAVLLTGA 62 Query: 91 D-KAFAAGADIKEMQNLSFQDCYSSKFL-----KHWDHLTQVKKPVIAAVNGYAFGGGCE 144 + AG D+ + + + D ++ + H+ + KP ++ ++G GGG Sbjct: 63 GERGLCAGGDVVAIYHSAKADGAEARRFWFDEYRLNAHIGRYPKPYVSIMDGIVMGGGVG 122 Query: 145 LAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAK 204 + ++ + + A PE+ IG IP GGT L+RA GK L + LTG S DA Sbjct: 123 VGAHGNVRVVTDTTKMAMPEVGIGFIPDVGGTYLLSRAPGK-LGLHAALTGAPFSGADAI 181 Query: 205 QAGLVSKICPVETLVEEAIQ-------------------------------------CAE 227 G P + + E A+ Sbjct: 182 VMGFADHYVPHDKIDEFTRAVIADGVDAALAAHAQEPPASPLAEQRSWIDECYTGDTVAD 241 Query: 228 KIAS------------------NSKIVVAMAKESVNAAFE-MTLTEGSKLEKKLFYSTFA 268 IA+ S I +++ ESV A + +L + + E ++ ++ Sbjct: 242 IIAALRAHDAPAAGEAADLIATRSPIALSVTLESVRRAAKLQSLEDTLRQEYRVSCASLK 301 Query: 269 TDDRKEGMTAFV--EKRKANFK 288 + D EG+ A + + R ++ Sbjct: 302 SHDLVEGIRAQLVDKDRNPKWR 323 >2NP9-A nrPDB Length = 440 Score = 146 bits (368), Expect = 1e-35, Method: Composition-based stats. Identities = 70/294 (23%), Positives = 119/294 (40%), Gaps = 39/294 (13%) Query: 6 VLLSCVRGP------LRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALN 59 VL S + GP LRP R P + A + + V + + R LN Sbjct: 130 VLRSPLAGPHLLDAMLRPTPRALELLPEFVRTGEVEMEAVHLERRDGVARLTMCRDDRLN 189 Query: 60 ALCDGLIDELNQALKTFEEDPAVGAIVLTGG---------DKAFAAGADIKEMQNLSFQ- 109 A +D++ A+ DP V +L GG + F+AG ++K + Sbjct: 190 AEDGQQVDDMETAVDLALLDPGVRVGLLRGGVMSHPRYRGKRVFSAGINLKYLSQGGISL 249 Query: 110 -DCYSSKFLKH----------------WDHLTQVKKPVIAAVNGYAFGGGCELAMMCDII 152 D + L + W H +++KP +AAV+G+A GGG +L ++ D + Sbjct: 250 VDFLMRRELGYIHKLVRGVLTNDDRPGWWHSPRIEKPWVAAVDGFAIGGGAQLLLVFDRV 309 Query: 153 YAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKI 212 A A F+ P G IPGA RL R G ++ +++L G RI A++ + LV ++ Sbjct: 310 LASSDAYFSLPAAKEGIIPGAANL-RLGRFAGPRVSRQVILEGRRIWAKEPEARLLVDEV 368 Query: 213 CPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYST 266 + L + ++ ++ + +N A E +G + F Sbjct: 369 VEPDELDAAIERSLTRLDGDAVLANR---RMLNLADESP--DGFRAYMAEFALM 417 >4HC8-A nrPDB Length = 255 Score = 138 bits (347), Expect = 3e-33, Method: Composition-based stats. Identities = 49/226 (21%), Positives = 85/226 (37%), Gaps = 4/226 (1%) Query: 43 KNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKE 102 + +++ +I ++ K +NAL + LN A+ + D VGA+V+TG + F+ G D+K Sbjct: 11 RKDSIAVISMDDGK-VNALGPAMQQALNAAIDNADRDD-VGALVITGNGRVFSGGFDLKI 68 Query: 103 MQNLSFQDC--YSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQF 160 + + Q + L KPV+ A G+A G L D A Sbjct: 69 LTSGEVQPAIDMLRGGFELAYRLLSYPKPVVMACTGHAIAMGAFLLSCGDHRVAAHAYNI 128 Query: 161 AQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVE 220 E+ IG + + + +S + + A AG + +I E +V Sbjct: 129 QANEVAIGMTIPYAALEIMKLRLTRSAYQQATGLAKTFFGETALAAGFIDEIALPEVVVS 188 Query: 221 EAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYST 266 A + A + A ++ A K A + G F Sbjct: 189 RAEEAAREFAGLNQHAHAATKLRSRADALTAIRAGIDGIAAEFGLA 234 >3JU1-A nrPDB Length = 407 Score = 138 bits (347), Expect = 4e-33, Method: Composition-based stats. Identities = 59/206 (28%), Positives = 91/206 (44%), Gaps = 13/206 (6%) Query: 22 PAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPA 81 A FA+ +A GK VG++ LN KALNAL ++ + L +++DP Sbjct: 29 KAAHSFATQNVVFQTLATASGKL--VGVVTLNVEKALNALDLDMVRAMTVQLNLWKKDPL 86 Query: 82 VGAIVLTG-GDKAFAAGADIKEMQNLSFQD---------CYSSKFLKHWDHLTQVKKPVI 131 + +VL G G+KAF AG D++ + + S + + + L KPV+ Sbjct: 87 IACVVLDGSGEKAFCAGGDVRALYHASVAAKGQVTEVAKVFFEEEYRLDYLLHTYGKPVL 146 Query: 132 AAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEM 191 +G GGG L E ++ A PE+ IG P GG+ L R GK + + + Sbjct: 147 VWGDGIVMGGGLGLMAGASHKVVTETSRIAMPEVTIGLYPDVGGSYFLNRMPGK-MGLFL 205 Query: 192 VLTGDRISAQDAKQAGLVSKICPVET 217 LT ++A DA GL + Sbjct: 206 GLTAYHMNAADACYVGLADHYLNRDD 231 >4B3J-A nrPDB Length = 736 Score = 131 bits (330), Expect = 3e-31, Method: Composition-based stats. Identities = 56/202 (27%), Positives = 91/202 (45%), Gaps = 11/202 (5%) Query: 44 NNTVGLIQLNRPK-ALNALCDGLIDELNQALKT-FEEDPAVGAIVLTGGDKAFAAGADIK 101 + + + ++ P + N + + I+ + +A+ E ++ +V+ K F AG D+K Sbjct: 28 ADGIVTLTMDDPSGSTNVMNEAYIESMGKAVDRLVAEKDSITGVVVASAKKTFFAGGDVK 87 Query: 102 EMQNLSFQDCYS-----SKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGE 156 M +D + L + KPV+AA+NG A GGG E+A+ C A + Sbjct: 88 TMIQARPEDAGDVFNTVETIKRQLRTLETLGKPVVAAINGAALGGGLEIALACHHRIAAD 147 Query: 157 --KAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVL-TGDRISAQDAKQAGLVSK-I 212 +Q PE+ +G +PG GG R R G A VL G R AK+ GLV + + Sbjct: 148 VKGSQLGLPEVTLGLLPGGGGVTRTVRMFGIQNAFVSVLAQGTRFKPAKAKEIGLVDELV 207 Query: 213 CPVETLVEEAIQCAEKIASNSK 234 VE LV A ++ + Sbjct: 208 ATVEELVPAAKAWIKEELKANP 229 >4ZDC-A nrPDB Length = 300 Score = 128 bits (323), Expect = 2e-30, Method: Composition-based stats. Identities = 50/238 (21%), Positives = 87/238 (36%), Gaps = 28/238 (11%) Query: 49 LIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSF 108 +I L P LNAL L + L+ + + V ++ + F++GAD K + Sbjct: 41 IIHLINPDNLNALEGEDYIYLGELLELADRNRDVYFTIIQSSGRFFSSGADFKGIAKAQG 100 Query: 109 QDCY-----SSKFLKHW--------DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA- 154 D +SK++ ++ D + K +I +NG A G L +CDI+Y+ Sbjct: 101 DDTNKYPSETSKWVSNFVARNVYVTDAFIKHSKVLICCLNGPAIGLSAALVALCDIVYSI 160 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKIC- 213 +K P +G I G T L G + E ++ + G +SK Sbjct: 161 NDKVYLLYPFANLGLITEGGTTVSLPLKFGTNTTYECLMFNKPFKYDIMCENGFISKNFN 220 Query: 214 -PVETLVEEAIQCAEKIASNS-----KIVVAMAK-------ESVNAAFEMTLTEGSKL 258 P + E++ + M K ++ N A + + E K Sbjct: 221 MPSSNAEAFNAKVLEELREKVKGLYLPSCLGMKKLLKSNHIDAFNKANSVEVNESLKY 278 >3M6N-A nrPDB Length = 305 Score = 110 bits (275), Expect = 7e-25, Method: Composition-based stats. Identities = 42/183 (22%), Positives = 70/183 (38%), Gaps = 12/183 (6%) Query: 85 IVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQ----------VKKPVIAAV 134 +VL F G D+ L ++ ++ L + + + IA V Sbjct: 89 VVLASDSDVFNLGGDLALFCQL-IREGDRARLLDYAQRCVRGVHAFHVGLGARAHSIALV 147 Query: 135 NGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLT 194 G A GGG E A+ C I A E PE+L PG G + + + LA +++L Sbjct: 148 QGNALGGGFEAALSCHTIIAEEGVMMGLPEVLFDLFPGMGAYSFMCQRISAHLAQKIMLE 207 Query: 195 GDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTE 254 G+ SA+ GLV ++ P V Q + + + A ++ + L E Sbjct: 208 GNLYSAEQLLGMGLVDRVVPRGQGVAAVEQVIRE-SKRTPHAWAAMQQVREMTTAVPLEE 266 Query: 255 GSK 257 + Sbjct: 267 MMR 269 >3BF0-A nrPDB Length = 593 Score = 41.5 bits (96), Expect = 4e-04, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 57/203 (28%), Gaps = 59/203 (29%) Query: 70 NQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKP 129 ++ DP V AIVL + + S KP Sbjct: 328 AAQIRDARLDPKVKAIVLR--------------VNSPGGSVTASEVIRAELAAARAAGKP 373 Query: 130 VIAAVNGYAFGGGCELAMMCDIIYAGEKA------QFAQPEI------LIGTIPGAGGTQ 177 V+ ++ G A GG ++ + I A F IG T Sbjct: 374 VVVSMGGMAASGGYWISTPANYIVANPSTLTGSIGIFGVITTVENSLDSIGVHTDGVSTS 433 Query: 178 RL-----TRAVGKSLAMEMVLT----------------------------GDRISAQDAK 204 L TRA+ + M L+ G + QDAK Sbjct: 434 PLADVSITRALPPEAQLMMQLSIENGYKRFITLVADARHSTPEQIDKIAQGHVWTGQDAK 493 Query: 205 QAGLVSKICPVETLVEEAIQCAE 227 GLV + + V +A + A+ Sbjct: 494 ANGLVDSLGDFDDAVAKAAELAK 516 >1V3M-A nrPDB Length = 686 Score = 33.4 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 36/184 (19%), Positives = 60/184 (32%), Gaps = 20/184 (10%) Query: 13 GPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQA 72 PLR A+ +I +R N V ++ +NR N I L + Sbjct: 395 APLRKSNPAIAYGSTHERWINNDVIIYERKFGNNVAVVAINR----NMNTPASITGLVTS 450 Query: 73 LKTFEEDPAVGAIV----LTGGDKAFAAGADIKEMQNL--SFQDCYSSKFLKHWDHLTQV 126 L + +G I+ LT G A+ + + ++ + + + Sbjct: 451 LPRGSYNDVLGGILNGNTLTVGAGGAASNFTLAPGGTAVWQYTTDATTPIIGNVGPMMAK 510 Query: 127 KKPVIAAVNGYAFGGGCE------LAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLT 180 I ++G FG G A+ I A E Q + I +PG R+ Sbjct: 511 PGVTIT-IDGRGFGSGKGTVYFGTTAVTGADIVAWEDTQIQ---VKIPAVPGGIYDIRVA 566 Query: 181 RAVG 184 A G Sbjct: 567 NAAG 570 >1QDB-A nrPDB Length = 473 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 19/126 (15%), Positives = 44/126 (34%), Gaps = 17/126 (13%) Query: 149 CDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL 208 D+ A F PE + + A G A + + + + G+ Sbjct: 358 ADMAIAAHGNYFHAPEETLRLL-----------AAGSDDAQK----ARLLLVKILAKHGV 402 Query: 209 VSKICPVETLVEEAIQCAE-KIASNSKIVVAMAKESVNAAFEMTLTEGSKLEKKLFYSTF 267 + I P ++A + A+ IA+ + + K+++ ++ + +L+ Sbjct: 403 MDYIAPDFDTKDKAQKLAKVDIAALAAEKMKF-KQTLEQEWKKEAKAKGRANPELYKDVD 461 Query: 268 ATDDRK 273 +D K Sbjct: 462 TINDGK 467 >3SN5-A nrPDB Length = 491 Score = 31.9 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 20/88 (22%), Positives = 38/88 (43%), Gaps = 6/88 (6%) Query: 55 PKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFA------AGADIKEMQNLSF 108 ALN+L + +++ L + ++ + A +T G +F AG ++L+ Sbjct: 118 GHALNSLTESMMENLQRIMRPPVSSNSKTAAWVTEGMYSFCYRVMFEAGYLTIFGRDLTR 177 Query: 109 QDCYSSKFLKHWDHLTQVKKPVIAAVNG 136 +D + L + D+ Q K A V G Sbjct: 178 RDTQKAHILNNLDNFKQFDKVFPALVAG 205 >4KWB-A nrPDB Length = 273 Score = 31.1 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 43/119 (36%), Gaps = 17/119 (14%) Query: 66 IDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQ 125 + L+ ++D V IVL K + G + E + + K + Sbjct: 36 HRTFLKNLERAKDDKTVKGIVL----KVNSPGGGVYESAEIHKKLEEIKK---------E 82 Query: 126 VKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVG 184 KKP+ ++ A GG ++ D I+A + +G I + +L +G Sbjct: 83 TKKPIYVSMGSMAASGGYYISTAADKIFATPETLTG----SLGVIMESVNYSKLADKLG 137 >3RST-A nrPDB Length = 240 Score = 31.1 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 43/119 (36%), Gaps = 17/119 (14%) Query: 66 IDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQ 125 + L+ ++D V IVL K + G + E + + K + Sbjct: 31 HRTFLKNLERAKDDKTVKGIVL----KVNSPGGGVYESAEIHKKLEEIKK---------E 77 Query: 126 VKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVG 184 KKP+ ++ A GG ++ D I+A + +G I + +L +G Sbjct: 78 TKKPIYVSMGSMAASGGYYISTAADKIFATPETLTG----SLGVIMESVNYSKLADKLG 132 >3MH6-A nrPDB Length = 456 Score = 30.7 bits (68), Expect = 0.71, Method: Composition-based stats. Identities = 39/231 (16%), Positives = 79/231 (34%), Gaps = 35/231 (15%) Query: 27 FASGANFEYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIV 86 + G F+ + K +++ + LIQ+ PK L A+ D L D V Sbjct: 117 LSDGRKFDAKMVGKDPRSD-IALIQIQNPKNLTAIKMADSDALRV------GDYTVAIGN 169 Query: 87 LTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELA 146 G + +G + + F++ + + GG + Sbjct: 170 PFGLGETVTSGI-VSALGRSGLNAENYENFIQTDAAINRGN------------SGGALVN 216 Query: 147 MMCDIIYAGEKAQFAQPEILIGT---IPGAGGTQRLTRAV--GKSLAMEMVLTGDRISAQ 201 + ++ A A IG IP ++ V G+ E+ + G ++++ Sbjct: 217 LNGEL-IGINTAILAPDGGNIGIGFAIPSNMVKNLTSQMVEYGQVKRGELGIMGTELNSE 275 Query: 202 -------DAKQAGLVSKICPVETLVEEAIQCAEKIASNS--KIVVAMAKES 243 DA++ VS++ P + + I+ + I S + I A + Sbjct: 276 LAKAMKVDAQRGAFVSQVLPNSSAAKAGIKAGDVITSLNGKPISSFAALRA 326 >3U9S-B nrPDB Length = 555 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 23/145 (15%), Positives = 46/145 (31%), Gaps = 31/145 (21%) Query: 95 AAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYA 154 + GA++ + + + + +++ P IA V G GG + M D Sbjct: 165 SGGANLPRQDEVFPDREHFGRIFFNQANMSARGIPQIAVVMGSCTAGGAYVPAMSDETVM 224 Query: 155 GEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQD-------AKQAG 207 + Q G L TG+ +SA++ K +G Sbjct: 225 VRE-------------------QATIFLAGPPLVKAA--TGEVVSAEELGGADVHCKVSG 263 Query: 208 LVSKICPVETLVEEAIQCAEKIASN 232 + + + A+ A + +N Sbjct: 264 VADHYAEDD---DHALAIARRCVAN 285 >6MZL-P nrPDB Length = 211 Score = 29.6 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 193 LTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNA 246 +TG +S +SK+ V +VEEA+ EK + +E+V Sbjct: 141 ITGTSVSQNVVIAMSGISKVF-VGEVVEEALDVCEKWGEMPPLQPKHMREAVRR 193 >1ON3-A nrPDB Length = 523 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 33/178 (18%), Positives = 58/178 (32%), Gaps = 31/178 (17%) Query: 86 VLTGGDKAF---AAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKK-PVIAAVNGYAFGG 141 +LTG F + GA I+E D S + ++ P IA + G GG Sbjct: 127 LLTGTPFLFFYDSGGARIQE-----GIDSLSGYGKMFFANVKLSGVVPQIAIIAGPCAGG 181 Query: 142 GCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLTRAVGKSLAMEMVLTGDRISAQ 201 + D I +KA I G + + ++ T D + Sbjct: 182 ASYSPALTDFIIMTKKAHM--------FITG-------PQVIKSVTGEDV--TADELGGA 224 Query: 202 DAKQA--GLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTEGSK 257 +A A G + + + + A A+K+ S VN +++ + Sbjct: 225 EAHMAISGNIHFVAEDD---DAAELIAKKLLSFLPQNNTEEASFVNPNNDVSPNTELR 279 >1BH8-B nrPDB Length = 89 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 193 LTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNA 246 +TG +S +SK+ V +VEEA+ EK + +E+V Sbjct: 29 ITGTSVSQNVVIAMSGISKVF-VGEVVEEALDVCEKWGEMPPLQPKHMREAVRR 81 >3EEQ-A nrPDB Length = 336 Score = 29.2 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%), Gaps = 13/64 (20%) Query: 83 GAIVLTGGDKAFAAGADIKE--------MQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAV 134 G +++ + AF+AG IKE + + ++D K +D + + A+ Sbjct: 10 GICIISASEDAFSAGETIKEKLKSFEIPVVHYRYKDAEIETIWKCYDAI-----VFVMAL 64 Query: 135 NGYA 138 G Sbjct: 65 EGAT 68 >2YJN-B nrPDB Length = 381 Score = 28.8 bits (63), Expect = 2.7, Method: Composition-based stats. Identities = 27/167 (16%), Positives = 47/167 (28%), Gaps = 16/167 (9%) Query: 102 EMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVN----GYAFGGGCELAMMCDII----Y 153 + ++ F + + P + + G G G L ++ D Sbjct: 109 MRAAGAPPAEWAQPFRDVHAASWEGEVPDVGELAESFAGLLPGAGARLDLVGDFAWQVPV 168 Query: 154 AGEKAQFAQPEILIGTIPGAGGT---QRLTRAVGKSLAMEMVLTGDRISAQDAKQAGL-- 208 G A +L G A + Q + + + A L D A A AG Sbjct: 169 QGMTAVLGAAGVLRGAAWDARVSLDAQLSPQQLAVTEAAVAALPADP--ALRALFAGAEM 226 Query: 209 -VSKICPVETLVEEAIQCAEKIASNSKIVVAMAKESVNAAFEMTLTE 254 + + V AE+IA + E + + L Sbjct: 227 TANTVVDAVLAVSAEPGLAERIADDPAAAQRTVAEVLRLHPALHLER 273 >1A6E-A nrPDB Length = 545 Score = 28.4 bits (62), Expect = 3.4, Method: Composition-based stats. Identities = 15/65 (23%), Positives = 27/65 (41%), Gaps = 1/65 (1%) Query: 34 EYIIAEKRGKNNTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAVGAIVLTGGDKA 93 E + K G + ++ PKA++ L G D + ++ D A+ + +T D Sbjct: 345 ETVEERKIGDDRMTFVMGCKNPKAVSILIRGGTDHVVSEVERALND-AIRVVAITKEDGK 403 Query: 94 FAAGA 98 F G Sbjct: 404 FLWGG 408 >2C8T-A nrPDB Length = 206 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 7/27 (25%), Positives = 11/27 (40%) Query: 196 DRISAQDAKQAGLVSKICPVETLVEEA 222 +A +A + G V I + EA Sbjct: 174 RWFTAAEALEYGFVDHIITRAHVNGEA 200 >6B5B-F nrPDB Length = 566 Score = 28.0 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 28/113 (24%), Gaps = 34/113 (30%) Query: 45 NTVGLIQLNRPKALNALCDGLIDELNQALKTFEEDPAV----------------GAIVLT 88 N V + LN +L A+ V I +T Sbjct: 352 NGVAIYT-----NLNVATALTNSDLRDAINGVSNQTGVVASLNGGNMTLTAADGRNITVT 406 Query: 89 GGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGG 141 F AG D + +F I+AV+ A GG Sbjct: 407 ESGTGFTAGTDGLTVTGGAFDGALRGTL-------------SISAVDTIAIGG 446 >2GQD-A nrPDB Length = 437 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 28/139 (20%), Positives = 47/139 (33%), Gaps = 2/139 (1%) Query: 85 IVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHWDHLTQVKKPVIAAVNGYAFGGGCE 144 IV G A G + +++ +S+ L D + +P +G+ G G Sbjct: 201 IVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPFQEGRDGFVMGEGAG 260 Query: 145 LAMMCDIIYA-GEKAQFAQPEILIGTIPGAG-GTQRLTRAVGKSLAMEMVLTGDRISAQD 202 + ++ + A A + GT A T G S AM+ + I +D Sbjct: 261 ILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIEPKD 320 Query: 203 AKQAGLVSKICPVETLVEE 221 + PV L E Sbjct: 321 VQYLNAHGTSTPVGDLNEV 339 >3QWD-A nrPDB Length = 203 Score = 27.6 bits (60), Expect = 5.6, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 35/108 (32%), Gaps = 25/108 (23%) Query: 134 VNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQ---------------- 177 V G + + + +FA P + GG Q Sbjct: 88 VQTICIGMAASMGSFL-LAAGAKGKRFALPNAEVMIHQPLGGAQGQATEIEIAANHILKT 146 Query: 178 --RLTRAVGKSLAMEM------VLTGDRISAQDAKQAGLVSKICPVET 217 +L R + + + + ++A++AK+ GL+ ++ ET Sbjct: 147 REKLNRILSERTGQSIEKIQKDTDRDNFLTAEEAKEYGLIDEVMVPET 194 >5Z9A-A nrPDB Length = 363 Score = 27.3 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 15/89 (16%), Positives = 19/89 (21%), Gaps = 17/89 (19%) Query: 59 NAL---CDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSK 115 NA + EL + D + GA I + Sbjct: 175 NAFFSPDPDKVPELEAYMDQLRRDQD-------------SVGAKITVVAE-GVPPGLGEP 220 Query: 116 FLKHWDHLTQVKKPVIAAVNGYAFGGGCE 144 D I AV G G G Sbjct: 221 IFDRLDAELAHALMSINAVKGVEIGAGFA 249 >1PWH-A nrPDB Length = 327 Score = 26.9 bits (58), Expect = 9.7, Method: Composition-based stats. Identities = 12/60 (20%), Positives = 26/60 (43%), Gaps = 2/60 (3%) Query: 175 GTQRLTRAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSK 234 T R +G + + T ++ + K G ++ +++EAIQ A+ + N+ Sbjct: 71 ATAYAARRLGLPATIVVPSTTPALTIERLKNEGATVEVV--GEMLDEAIQLAKALEKNNP 128 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.142 0.381 Lambda K H 0.267 0.0428 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,769,093 Number of Sequences: 36641 Number of extensions: 417600 Number of successful extensions: 1787 Number of sequences better than 10.0: 90 Number of HSP's better than 10.0 without gapping: 113 Number of HSP's successfully gapped in prelim test: 39 Number of HSP's that attempted gapping in prelim test: 1484 Number of HSP's gapped (non-prelim): 160 length of query: 290 length of database: 10,336,785 effective HSP length: 96 effective length of query: 194 effective length of database: 6,819,249 effective search space: 1322934306 effective search space used: 1322934306 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 59 (27.3 bits)