BLASTP 2.2.23 [Feb-03-2010]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Reference for compositional score matrix adjustment: Altschul, Stephen F.,
John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis,
Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches
using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109.
Reference for composition-based statistics starting in round 2:
Schaffer, Alejandro A., L. Aravind, Thomas L. Madden,
Sergei Shavirin, John L. Spouge, Yuri I. Wolf,
Eugene V. Koonin, and Stephen F. Altschul (2001),
"Improving the accuracy of PSI-BLAST protein database searches with
composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005.
Query= P29717
(438 letters)
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
36,641 sequences; 10,336,785 total letters
Searching..................................................done
Results from round 1
Score E
Sequences producing significant alignments: (bits) Value
2PBO-A nrPDB 825 0.0
1H4P-A nrPDB 494 e-140
1CEO-A nrPDB 62 6e-10
1VJZ-A nrPDB 40 0.002
3NCO-A nrPDB 38 0.009
4W7V-A nrPDB 37 0.013
3W0K-A nrPDB 35 0.049
1V3M-A nrPDB 35 0.055
1A47-A nrPDB 33 0.31
2VRK-A nrPDB 31 0.87
4M24-A nrPDB 31 1.0
4OEP-A nrPDB 30 1.7
5IG4-A nrPDB 30 2.8
1IYN-A nrPDB 30 2.9
2OYK-A nrPDB 30 2.9
5H4R-A nrPDB 29 3.4
3AZS-A nrPDB 29 4.6
5E0C-A nrPDB 29 4.7
1UR0-A nrPDB 28 5.3
4JIE-A nrPDB 28 8.6
>2PBO-A nrPDB
Length = 400
Score = 825 bits (2131), Expect = 0.0, Method: Compositional matrix adjust.
Identities = 397/400 (99%), Positives = 399/400 (99%)
Query: 39 GGGHNVAWDYDNNVIRGVNLGGWFVLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK 98
GGGHNVAWDYDNNVIRGVNLGGWFVL+PYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK
Sbjct: 1 GGGHNVAWDYDNNVIRGVNLGGWFVLQPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK 60
Query: 99 EAASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKAL 158
EAA RILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKAL
Sbjct: 61 EAALRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKAL 120
Query: 159 GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEY 218
GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEY
Sbjct: 121 GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEY 180
Query: 219 SDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT 278
SDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT
Sbjct: 181 SDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT 240
Query: 279 VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC 338
VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC
Sbjct: 241 VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC 300
Query: 339 AKWLNGVNRGARYEGAYDNAPYIGSCQPMLDISQWSDEHKTDTRRYIEAQLDAFEYTGGW 398
AKWLNGVNRGARYEGAYDNAPYIGSCQP+LDISQWSDEHKTDTRRYIEAQLDAFEYTGGW
Sbjct: 301 AKWLNGVNRGARYEGAYDNAPYIGSCQPLLDISQWSDEHKTDTRRYIEAQLDAFEYTGGW 360
Query: 399 VFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH 438
VFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH
Sbjct: 361 VFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH 400
>1H4P-A nrPDB
Length = 408
Score = 494 bits (1272), Expect = e-140, Method: Compositional matrix adjust.
Identities = 241/403 (59%), Positives = 298/403 (73%), Gaps = 12/403 (2%)
Query: 46 WDYDNNV----IRGVNLGGWFVLEPYMTPSLFEPFQNGND-QSGVPVDEYHWTQTLGKEA 100
+DYD+ IRGVN+GGW +LEPY+TPSLFE F+ +D G+PVDEYH+ Q LGK+
Sbjct: 2 YDYDHGSLGEPIRGVNIGGWLLLEPYITPSLFEAFRTNDDNDEGIPVDEYHFCQYLGKDL 61
Query: 101 ASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQG-QVQYLEKALG 159
A LQ HWST+ EQDF I++ G N VRIPIGYWAFQ+LD+DPYV G Q YL++A+G
Sbjct: 62 AKSRLQSHWSTFYQEQDFANIASQGFNLVRIPIGYWAFQILDDDPYVSGLQESYLDQAIG 121
Query: 160 WARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYS 219
WAR N+++VW+DLHGA GSQNGFDNSGLRDSY F N VT+NVLN I KKY EY
Sbjct: 122 WARNNSLKVWVDLHGAAGSQNGFDNSGLRDSYKFLEDSNLAVTINVLNYILKKYSAEEYL 181
Query: 220 DVVIGIELLNEPLGPVLNMDKLKQFFLD-GYNSLR-QTGSVTPVIIHDAFQVFGYWNNFL 277
D+VIGIEL+NEPLGPVL+MDK+K +L Y LR S +IIHDAFQ + YW++F+
Sbjct: 182 DIVIGIELINEPLGPVLDMDKMKNDYLAPAYEYLRNNIKSDQVIIIHDAFQPYNYWDDFM 241
Query: 278 TVAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTD 337
T +G W V +DHHHYQVF+ +L R+I++HI VAC WG ESHW V GE++AALTD
Sbjct: 242 TENDGYWGVTIDHHHYQVFASDQLERSIDEHIKVACEWGTGVLNESHWIVCGEFAAALTD 301
Query: 338 CAKWLNGVNRGARYEGAYDN----APYIGSCQPMLDISQWSDEHKTDTRRYIEAQLDAFE 393
C KWLN V GARY+G++ N + YIGSC DI+ WSDE K +TRRY+EAQLDAFE
Sbjct: 302 CIKWLNSVGFGARYDGSWVNGDQTSSYIGSCANNDDIAYWSDERKENTRRYVEAQLDAFE 361
Query: 394 YTGGWVFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCG 436
GGW+ W +KTE++ EW Q L +NGLFPQP+TDR++PNQCG
Sbjct: 362 MRGGWIIWCYKTESSLEWDAQRLMFNGLFPQPLTDRKYPNQCG 404
>1CEO-A nrPDB
Length = 343
Score = 61.6 bits (148), Expect = 6e-10, Method: Compositional matrix adjust.
Identities = 40/156 (25%), Positives = 79/156 (50%), Gaps = 12/156 (7%)
Query: 106 QKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDN-DPYVQGQVQYLEKALGWARKN 164
++H+ T+ITE+D + I+ G + VR+P Y + DN Y + + Y+++ L W +K
Sbjct: 22 KEHFDTFITEKDIETIAEAGFDHVRLPFDYPIIESDDNVGEYKEDGLSYIDRCLEWCKKY 81
Query: 165 NIRVWIDLHGAPGSQ-NGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVI 223
N+ + +D+H APG + F S L F++ + + +++ + K+Y I
Sbjct: 82 NLGLVLDMHHAPGYRFQDFKTSTL-----FEDPNQQKRFVDIWRFLAKRYINEREH---I 133
Query: 224 GIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVT 259
ELLN+ + P + + + L+ ++R+ S
Sbjct: 134 AFELLNQVVEP--DSTRWNKLMLECIKAIREIDSTM 167
>1VJZ-A nrPDB
Length = 341
Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust.
Identities = 35/155 (22%), Positives = 68/155 (43%), Gaps = 12/155 (7%)
Query: 115 EQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWARKNNIRVWIDL 172
E+DF ++ NFVRIP+ + + N P++ + + +++ + W K I + I L
Sbjct: 39 EEDFLWMAQWDFNFVRIPMCHLLWSDRGN-PFIIREDFFEKIDRVIFWGEKYGIHICISL 97
Query: 173 HGAPGSQNGFDNSGLRDSYNFQNGDNTQ-VTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
H APG N + + N + Q ++ + I ++Y G S + L+NEP
Sbjct: 98 HRAPGYSV---NKEVEEKTNLWKDETAQEAFIHHWSFIARRYKG--ISSTHLSFNLINEP 152
Query: 232 LGP---VLNMDKLKQFFLDGYNSLRQTGSVTPVII 263
P +++++ +R+ +II
Sbjct: 153 PFPDPQIMSVEDHNSLIKRTITEIRKIDPERLIII 187
>3NCO-A nrPDB
Length = 320
Score = 37.7 bits (86), Expect = 0.009, Method: Compositional matrix adjust.
Identities = 53/241 (21%), Positives = 97/241 (40%), Gaps = 38/241 (15%)
Query: 105 LQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWAR 162
++ W +I ++ FK I G + VRIPI W+ + + PY + + ++ + A
Sbjct: 34 VEGSWGVYIEDEYFKIIKERGFDSVRIPIR-WSAHISEKYPYEIDKFFLDRVKHVVDVAL 92
Query: 163 KNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGG--NEYSD 220
KN++ V I+ H D G VL I+K+ +Y D
Sbjct: 93 KNDLVVIINCHHFEELYQAPDKYG-----------------PVLVEIWKQVAQAFKDYPD 135
Query: 221 VVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLTVA 280
+ E+ NEP L K + + +R+T VII W+N+ V
Sbjct: 136 KLF-FEIFNEP-AQNLTPTKWNELYPKVLGEIRKTNPSRIVIID-----VPNWSNYSYVR 188
Query: 281 EGQW----NVVVDHHHYQVFSGGELSRN-INDHISVACNW---GWDAKK-ESHWNVAGEW 331
E + N++V H+Y+ F+ ++ + + W W+ ++ +H+ EW
Sbjct: 189 ELKLVDDKNIIVSFHYYEPFNFTHQGAEWVSPTLPIGVKWEGKDWEVEQIRNHFKYVSEW 248
Query: 332 S 332
+
Sbjct: 249 A 249
>4W7V-A nrPDB
Length = 332
Score = 37.4 bits (85), Expect = 0.013, Method: Compositional matrix adjust.
Identities = 28/123 (22%), Positives = 51/123 (41%), Gaps = 13/123 (10%)
Query: 111 TWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWI 170
T+ DF + G+N +R+P + Q N P Q Q+ ++K+L A+ N + +
Sbjct: 48 TYPAASDFSYFAGKGMNTIRLPFLWERVQPELNGPLDQAQLGLIKKSLEAAKANKQYLIL 107
Query: 171 DLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNE 230
DLH +Y+ + + V L ++++ D + L+NE
Sbjct: 108 DLHN-------------YATYSGKRIGTSDVPAGALADLWRRLALEFKDDKAVIFGLMNE 154
Query: 231 PLG 233
P G
Sbjct: 155 PNG 157
>3W0K-A nrPDB
Length = 330
Score = 35.4 bits (80), Expect = 0.049, Method: Compositional matrix adjust.
Identities = 35/118 (29%), Positives = 53/118 (44%), Gaps = 17/118 (14%)
Query: 121 ISNLGLNFVRIPIGY--WA--FQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHGAP 176
++ G NFVRIP+ Y W F + D V +Y++ L NI + ++LH AP
Sbjct: 31 LAETGFNFVRIPVDYRFWTRNFDYFNPDKKV---FEYIDLYLRECSARNIHMCLNLHRAP 87
Query: 177 G---SQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
G ++N + L Q+G Q L K+Y G S + +L+NEP
Sbjct: 88 GYCINRNDIERDNLWLDKRAQDGFVYQWEL-----FAKRYKG--VSSKFLSFDLVNEP 138
>1V3M-A nrPDB
Length = 686
Score = 35.4 bits (80), Expect = 0.055, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 43/95 (45%), Gaps = 6/95 (6%)
Query: 134 GYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDL---HGAPGSQNGFDNSGLRDS 190
GYWA +P G +Q + + A +NI+V ID H +P S + D S +
Sbjct: 99 GYWARDFKKTNP-AYGTMQDFKNLIDTAHAHNIKVIIDFAPNHTSPASSD--DPSFAENG 155
Query: 191 YNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGI 225
+ NG+ N +F YGG ++S + GI
Sbjct: 156 RLYDNGNLLGGYTNDTQNLFHHYGGTDFSTIENGI 190
>1A47-A nrPDB
Length = 683
Score = 32.7 bits (73), Expect = 0.31, Method: Compositional matrix adjust.
Identities = 28/95 (29%), Positives = 40/95 (42%), Gaps = 6/95 (6%)
Query: 134 GYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDL---HGAPGSQNGFDNSGLRDS 190
GYWA +PY G + + A +NI+V ID H +P S+ D + +
Sbjct: 100 GYWARDFKRTNPYF-GSFTDFQNLINTAHAHNIKVIIDFAPNHTSPASET--DPTYAENG 156
Query: 191 YNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGI 225
+ NG N N F YGG ++S GI
Sbjct: 157 RLYDNGTLLGGYTNDTNGYFHHYGGTDFSSYEDGI 191
>2VRK-A nrPDB
Length = 496
Score = 31.2 bits (69), Expect = 0.87, Method: Compositional matrix adjust.
Identities = 20/69 (28%), Positives = 28/69 (40%), Gaps = 12/69 (17%)
Query: 84 GVPVDEYHWTQTLG-KEAASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLD 142
G DEYHW +G +E R++ HW I F + L +LL
Sbjct: 73 GCFADEYHWKDGVGPREKRKRMVNTHWGGVIENNHFGTHEFMML-----------CELLG 121
Query: 143 NDPYVQGQV 151
+PY+ G V
Sbjct: 122 CEPYISGNV 130
>4M24-A nrPDB
Length = 321
Score = 31.2 bits (69), Expect = 1.0, Method: Compositional matrix adjust.
Identities = 38/182 (20%), Positives = 74/182 (40%), Gaps = 21/182 (11%)
Query: 118 FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHGAPG 177
F+ S G++ VR P+ + Q N ++ L A++N+I+V +D+H
Sbjct: 35 FEYWSEQGIHTVRFPLKWERLQPSLNAELDDVYASLVDDMLDQAKENDIKVILDVH---- 90
Query: 178 SQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLGPVLN 237
+ + R +++ I K++ G+ D + +++NEP G +
Sbjct: 91 -----NYARYRKKVIGTEDVPVSAYQDLMERIAKRWQGH---DALFAYDIMNEPYG---S 139
Query: 238 MDKL-KQFFLDGYNSLRQTGSVTPVIIH-----DAFQVFGYWNNFLTVAEGQWNVVVDHH 291
DKL G + +R+ P++I A + Y + L + + N+V H
Sbjct: 140 ADKLWPAAAQAGIDGVRKYDKKRPLLIEGASWSSAARWPRYADELLKLKDPADNMVFSAH 199
Query: 292 HY 293
Y
Sbjct: 200 VY 201
>4OEP-A nrPDB
Length = 107
Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats.
Identities = 16/37 (43%), Positives = 23/37 (62%)
Query: 170 IDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVL 206
+ LH APG G SG RD+ +FQ+G+ + V +VL
Sbjct: 11 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVL 47
>5IG4-A nrPDB
Length = 145
Score = 29.6 bits (65), Expect = 2.8, Method: Compositional matrix adjust.
Identities = 16/49 (32%), Positives = 28/49 (57%), Gaps = 5/49 (10%)
Query: 63 VLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGKEAA---SRILQKH 108
+++P++T FEPF NGN G+ ++++ TL K + + IL H
Sbjct: 43 LVDPHVT--CFEPFSNGNLVEGLEFHKFYFDNTLSKRSVPINTTILSPH 89
>1IYN-A nrPDB
Length = 295
Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 20/64 (31%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 179 QNGFDNSGLRDSYNFQNGDNTQV--TLNVLNTIFKKYGGNEYSDV--VIGIELLNEPLGP 234
Q G N LR ++G N + LN+L I KY G Y+D+ + + E GP
Sbjct: 48 QRGGANGSLRFDVELKHGANAGLVNALNLLKPIKDKYSGVTYADLFQLASATAIEEAGGP 107
Query: 235 VLNM 238
+ M
Sbjct: 108 KIPM 111
>2OYK-A nrPDB
Length = 481
Score = 29.6 bits (65), Expect = 2.9, Method: Compositional matrix adjust.
Identities = 17/61 (27%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Query: 114 TEQDF-KQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDL 172
TE D ++ +++G NFVR I + + + Y Q + +E +GW + +V +D+
Sbjct: 67 TEADLAREYADMGTNFVRFLISWRSVEPAPGV-YDQQYLDRVEDRVGWYAERGYKVMLDM 125
Query: 173 H 173
H
Sbjct: 126 H 126
>5H4R-A nrPDB
Length = 396
Score = 29.3 bits (64), Expect = 3.4, Method: Compositional matrix adjust.
Identities = 33/163 (20%), Positives = 66/163 (40%), Gaps = 35/163 (21%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLH 173
T+Q + G N +RIP+ + N + + +++ + +A KN + V I++H
Sbjct: 82 TKQMIDTVKKAGFNTIRIPVSWHNHVTGSNFTISKRWLDRVQQVVDYAMKNKMYVIINIH 141
Query: 174 GAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGG--NEYSDVVIGIELLNEP 231
+ Y + N + Q ++ + +I+ + Y+D +I E +N+P
Sbjct: 142 -----------HDIMPGYYYPNSQHLQTSIKYVKSIWTQVATRFKNYNDHLI-FEAVNQP 189
Query: 232 ------------------LGPVLNMDKLKQFFLDGYNSLRQTG 256
V ++KL Q F+D ++R TG
Sbjct: 190 RLTGSRFEWWLDMNNPECRDAVEAINKLNQVFVD---TVRSTG 229
>3AZS-A nrPDB
Length = 317
Score = 28.9 bits (63), Expect = 4.6, Method: Compositional matrix adjust.
Identities = 43/196 (21%), Positives = 76/196 (38%), Gaps = 30/196 (15%)
Query: 109 WSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPY--VQGQVQYLEKALGWARKNNI 166
W I ++ F I G + VRIPI W+ PY + + +++ + A K +
Sbjct: 30 WGVVIKDEFFDIIKEAGFSHVRIPI-RWSTHAYAFPPYKIMDRFFKRVDEVINGALKRGL 88
Query: 167 RVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIE 226
V I++H N + ++ + L + I +Y +Y + + E
Sbjct: 89 AVVINIHHYEELMNDPE-------------EHKERFLALWKQIADRY--KDYPETLF-FE 132
Query: 227 LLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNF-----LTVAE 281
+LNEP G L +K + + +R +II A W L+V +
Sbjct: 133 ILNEPHGN-LTPEKWNELLEEALKVIRSIDKKHTIIIGTA-----EWGGISALEKLSVPK 186
Query: 282 GQWNVVVDHHHYQVFS 297
+ N +V H+Y F
Sbjct: 187 WEKNSIVTIHYYNPFE 202
>5E0C-A nrPDB
Length = 537
Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust.
Identities = 16/63 (25%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWARKNNIRVWI 170
+T + K I++ G +RIP+ W Q+ + Y + +E+ + WA + ++ V +
Sbjct: 42 VTRELIKTIADEGYKSIRIPVT-WENQMGNAPDYTINEDFFSRVEQVIDWALEEDLYVML 100
Query: 171 DLH 173
+LH
Sbjct: 101 NLH 103
>1UR0-A nrPDB
Length = 399
Score = 28.5 bits (62), Expect = 5.3, Method: Compositional matrix adjust.
Identities = 43/163 (26%), Positives = 65/163 (39%), Gaps = 30/163 (18%)
Query: 118 FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQY------LEKALGWARK---NNIRV 168
FK + G+N+VR+ I W NDPY Y LEKA+ ++ N +++
Sbjct: 54 FKTLKEAGVNYVRVRI--W------NDPYDANGNGYGGGNNDLEKAIQIGKRATANGMKL 105
Query: 169 WIDLH-----GAPGSQNGFDNSGLRDSYNFQNGDNT--QVTLNVLNTIFKKYGGNEYSDV 221
D H P Q + NF++ Q T L + K G + V
Sbjct: 106 LADFHYSDFWADPAKQKA---PKAWANLNFEDKKTALYQYTKQSLKAM--KAAGIDIGMV 160
Query: 222 VIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIH 264
+G E N L + K+ Q F G ++R+T S V +H
Sbjct: 161 QVGNE-TNGGLAGETDWAKMSQLFNAGSQAVRETDSNILVALH 202
>4JIE-A nrPDB
Length = 503
Score = 28.1 bits (61), Expect = 8.6, Method: Compositional matrix adjust.
Identities = 28/89 (31%), Positives = 43/89 (48%), Gaps = 15/89 (16%)
Query: 55 GVNLGGWFVLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGKEAASRILQKHWSTWIT 114
G+N +V E Y P++ +NG DQ G + + T G RI +++ +IT
Sbjct: 388 GINKAVTYVKETYGNPTMILS-ENGMDQPG------NVSITQGVHDTVRI--RYYRNYIT 438
Query: 115 EQDFKQISNLGLNFVRIPIGYWAFQLLDN 143
E K+ + G IGY+A+ LLDN
Sbjct: 439 E--LKKAIDDGAKV----IGYFAWSLLDN 461
Searching..................................................done
Results from round 2
Score E
Sequences producing significant alignments: (bits) Value
Sequences used in model and found again:
2PBO-A nrPDB 726 0.0
1H4P-A nrPDB 639 0.0
1CEO-A nrPDB 202 2e-52
Sequences not found previously or not previously below threshold:
1VJZ-A nrPDB 63 3e-10
3AZS-A nrPDB 57 2e-08
3NCO-A nrPDB 57 2e-08
3W0K-A nrPDB 57 2e-08
4W7V-A nrPDB 52 7e-07
4U5I-A nrPDB 50 2e-06
4M24-A nrPDB 50 3e-06
4LX4-A nrPDB 48 7e-06
4YZP-A nrPDB 43 3e-04
4W8B-A nrPDB 42 5e-04
4NF7-A nrPDB 40 0.001
3WFL-A nrPDB 40 0.002
5H4R-A nrPDB 40 0.003
2OYK-A nrPDB 38 0.009
1EDG-A nrPDB 38 0.010
4IM4-A nrPDB 38 0.011
5D8Z-A nrPDB 37 0.014
5E0C-A nrPDB 37 0.017
3NDZ-A nrPDB 37 0.019
6GL0-A nrPDB 35 0.061
1WKY-A nrPDB 35 0.063
1UR0-A nrPDB 34 0.10
1ECE-A nrPDB 34 0.16
2JEP-A nrPDB 33 0.17
4HU0-A nrPDB 33 0.19
5A94-A nrPDB 33 0.29
4V2X-A nrPDB 32 0.39
1PBG-A nrPDB 32 0.45
6A8M-A nrPDB 32 0.50
6HA9-A nrPDB 32 0.81
3ZMR-A nrPDB 31 1.0
4YHG-A nrPDB 31 1.3
3JUG-A nrPDB 31 1.3
1BGG-A nrPDB 31 1.4
5WKA-A nrPDB 30 1.5
4W84-A nrPDB 30 1.6
5IG4-A nrPDB 30 1.6
4XZW-A nrPDB 30 2.0
3MAN-A nrPDB 30 2.2
4XZB-A nrPDB 30 3.1
4OEP-A nrPDB 29 3.2
5MZA-A nrPDB 29 3.3
4R27-A nrPDB 29 3.8
3WE0-A nrPDB 29 3.9
4TUF-A nrPDB 29 3.9
3QHO-A nrPDB 29 4.4
6ID0-C nrPDB 29 4.9
4MPS-A nrPDB 28 7.6
2VRK-A nrPDB 28 7.7
3K4D-A nrPDB 28 8.4
>2PBO-A nrPDB
Length = 400
Score = 726 bits (1873), Expect = 0.0, Method: Composition-based stats.
Identities = 397/400 (99%), Positives = 399/400 (99%)
Query: 39 GGGHNVAWDYDNNVIRGVNLGGWFVLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK 98
GGGHNVAWDYDNNVIRGVNLGGWFVL+PYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK
Sbjct: 1 GGGHNVAWDYDNNVIRGVNLGGWFVLQPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK 60
Query: 99 EAASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKAL 158
EAA RILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKAL
Sbjct: 61 EAALRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKAL 120
Query: 159 GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEY 218
GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEY
Sbjct: 121 GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEY 180
Query: 219 SDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT 278
SDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT
Sbjct: 181 SDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT 240
Query: 279 VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC 338
VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC
Sbjct: 241 VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC 300
Query: 339 AKWLNGVNRGARYEGAYDNAPYIGSCQPMLDISQWSDEHKTDTRRYIEAQLDAFEYTGGW 398
AKWLNGVNRGARYEGAYDNAPYIGSCQP+LDISQWSDEHKTDTRRYIEAQLDAFEYTGGW
Sbjct: 301 AKWLNGVNRGARYEGAYDNAPYIGSCQPLLDISQWSDEHKTDTRRYIEAQLDAFEYTGGW 360
Query: 399 VFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH 438
VFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH
Sbjct: 361 VFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCGFH 400
>1H4P-A nrPDB
Length = 408
Score = 639 bits (1648), Expect = 0.0, Method: Composition-based stats.
Identities = 241/403 (59%), Positives = 298/403 (73%), Gaps = 12/403 (2%)
Query: 46 WDYDNNV----IRGVNLGGWFVLEPYMTPSLFEPFQNGND-QSGVPVDEYHWTQTLGKEA 100
+DYD+ IRGVN+GGW +LEPY+TPSLFE F+ +D G+PVDEYH+ Q LGK+
Sbjct: 2 YDYDHGSLGEPIRGVNIGGWLLLEPYITPSLFEAFRTNDDNDEGIPVDEYHFCQYLGKDL 61
Query: 101 ASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQG-QVQYLEKALG 159
A LQ HWST+ EQDF I++ G N VRIPIGYWAFQ+LD+DPYV G Q YL++A+G
Sbjct: 62 AKSRLQSHWSTFYQEQDFANIASQGFNLVRIPIGYWAFQILDDDPYVSGLQESYLDQAIG 121
Query: 160 WARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYS 219
WAR N+++VW+DLHGA GSQNGFDNSGLRDSY F N VT+NVLN I KKY EY
Sbjct: 122 WARNNSLKVWVDLHGAAGSQNGFDNSGLRDSYKFLEDSNLAVTINVLNYILKKYSAEEYL 181
Query: 220 DVVIGIELLNEPLGPVLNMDKLKQFFLD-GYNSLRQ-TGSVTPVIIHDAFQVFGYWNNFL 277
D+VIGIEL+NEPLGPVL+MDK+K +L Y LR S +IIHDAFQ + YW++F+
Sbjct: 182 DIVIGIELINEPLGPVLDMDKMKNDYLAPAYEYLRNNIKSDQVIIIHDAFQPYNYWDDFM 241
Query: 278 TVAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTD 337
T +G W V +DHHHYQVF+ +L R+I++HI VAC WG ESHW V GE++AALTD
Sbjct: 242 TENDGYWGVTIDHHHYQVFASDQLERSIDEHIKVACEWGTGVLNESHWIVCGEFAAALTD 301
Query: 338 CAKWLNGVNRGARYEGAYDN----APYIGSCQPMLDISQWSDEHKTDTRRYIEAQLDAFE 393
C KWLN V GARY+G++ N + YIGSC DI+ WSDE K +TRRY+EAQLDAFE
Sbjct: 302 CIKWLNSVGFGARYDGSWVNGDQTSSYIGSCANNDDIAYWSDERKENTRRYVEAQLDAFE 361
Query: 394 YTGGWVFWSWKTENAPEWSFQTLTYNGLFPQPVTDRQFPNQCG 436
GGW+ W +KTE++ EW Q L +NGLFPQP+TDR++PNQCG
Sbjct: 362 MRGGWIIWCYKTESSLEWDAQRLMFNGLFPQPLTDRKYPNQCG 404
>1CEO-A nrPDB
Length = 343
Score = 202 bits (515), Expect = 2e-52, Method: Composition-based stats.
Identities = 41/160 (25%), Positives = 81/160 (50%), Gaps = 12/160 (7%)
Query: 106 QKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDN-DPYVQGQVQYLEKALGWARKN 164
++H+ T+ITE+D + I+ G + VR+P Y + DN Y + + Y+++ L W +K
Sbjct: 22 KEHFDTFITEKDIETIAEAGFDHVRLPFDYPIIESDDNVGEYKEDGLSYIDRCLEWCKKY 81
Query: 165 NIRVWIDLHGAPGSQ-NGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVI 223
N+ + +D+H APG + F S L F++ + + +++ + K+Y I
Sbjct: 82 NLGLVLDMHHAPGYRFQDFKTSTL-----FEDPNQQKRFVDIWRFLAKRYINEREH---I 133
Query: 224 GIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVII 263
ELLN+ + P + + + L+ ++R+ S + I
Sbjct: 134 AFELLNQVVEP--DSTRWNKLMLECIKAIREIDSTMWLYI 171
>1VJZ-A nrPDB
Length = 341
Score = 62.7 bits (151), Expect = 3e-10, Method: Composition-based stats.
Identities = 31/156 (19%), Positives = 67/156 (42%), Gaps = 10/156 (6%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYV--QGQVQYLEKALGWARKNNIRVWI 170
E+DF ++ NFVRIP+ + +P++ + + +++ + W K I + I
Sbjct: 37 FKEEDFLWMAQWDFNFVRIPMCH-LLWSDRGNPFIIREDFFEKIDRVIFWGEKYGIHICI 95
Query: 171 DLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNE 230
LH APG + + +++ + ++ + I ++Y G S + L+NE
Sbjct: 96 SLHRAPGY--SVNKEVEEKTNLWKDETAQEAFIHHWSFIARRYKG--ISSTHLSFNLINE 151
Query: 231 PLGP---VLNMDKLKQFFLDGYNSLRQTGSVTPVII 263
P P +++++ +R+ +II
Sbjct: 152 PPFPDPQIMSVEDHNSLIKRTITEIRKIDPERLIII 187
>3AZS-A nrPDB
Length = 317
Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats.
Identities = 42/195 (21%), Positives = 72/195 (36%), Gaps = 30/195 (15%)
Query: 109 WSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYV--QGQVQYLEKALGWARKNNI 166
W I ++ F I G + VRIPI W+ PY + +++ + A K +
Sbjct: 30 WGVVIKDEFFDIIKEAGFSHVRIPI-RWSTHAYAFPPYKIMDRFFKRVDEVINGALKRGL 88
Query: 167 RVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIE 226
V I++H N ++ + L + I +Y + + E
Sbjct: 89 AVVINIHHYEELMND-------------PEEHKERFLALWKQIADRY---KDYPETLFFE 132
Query: 227 LLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNF-----LTVAE 281
+LNEP G L +K + + +R +II A W L+V +
Sbjct: 133 ILNEPHG-NLTPEKWNELLEEALKVIRSIDKKHTIIIGTA-----EWGGISALEKLSVPK 186
Query: 282 GQWNVVVDHHHYQVF 296
+ N +V H+Y F
Sbjct: 187 WEKNSIVTIHYYNPF 201
>3NCO-A nrPDB
Length = 320
Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats.
Identities = 49/233 (21%), Positives = 96/233 (41%), Gaps = 30/233 (12%)
Query: 109 WSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEK---ALGWARKNN 165
W +I ++ FK I G + VRIPI W+ + + PY + +L++ + A KN+
Sbjct: 38 WGVYIEDEYFKIIKERGFDSVRIPI-RWSAHISEKYPYEIDKF-FLDRVKHVVDVALKND 95
Query: 166 IRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGI 225
+ V I+ H D G V + + + + + +Y D +
Sbjct: 96 LVVIINCHHFEELYQAPDKYG-------------PVLVEIWKQVAQAF--KDYPDKLF-F 139
Query: 226 ELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIH-DAFQVFGYWNNFLTVAEGQW 284
E+ NEP L K + + +R+T VII + + Y V +
Sbjct: 140 EIFNEPAQ-NLTPTKWNELYPKVLGEIRKTNPSRIVIIDVPNWSNYSYVRELKLVDDK-- 196
Query: 285 NVVVDHHHYQVFS-GGELSRNINDHISVACNW---GWDAKK-ESHWNVAGEWS 332
N++V H+Y+ F+ + + ++ + + W W+ ++ +H+ EW+
Sbjct: 197 NIIVSFHYYEPFNFTHQGAEWVSPTLPIGVKWEGKDWEVEQIRNHFKYVSEWA 249
>3W0K-A nrPDB
Length = 330
Score = 56.6 bits (135), Expect = 2e-08, Method: Composition-based stats.
Identities = 35/157 (22%), Positives = 64/157 (40%), Gaps = 16/157 (10%)
Query: 115 EQDFKQISNLGLNFVRIPIGY--WAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDL 172
++ ++ G NFVRIP+ Y W +P + +Y++ L NI + ++L
Sbjct: 25 KKALDFLAETGFNFVRIPVDYRFWTRNFDYFNPDKK-VFEYIDLYLRECSARNIHMCLNL 83
Query: 173 HGAPGS---QNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLN 229
H APG +N + L Q+G + K+Y G S + +L+N
Sbjct: 84 HRAPGYCINRNDIERDNLWLDKRAQDG-----FVYQWELFAKRYKG--VSSKFLSFDLVN 136
Query: 230 EP--LGPV-LNMDKLKQFFLDGYNSLRQTGSVTPVII 263
EP +G L + + ++R+ ++I
Sbjct: 137 EPPNIGQYGLTRENHASLIIRTVEAIRKIDPDREIVI 173
>4W7V-A nrPDB
Length = 332
Score = 51.6 bits (122), Expect = 7e-07, Method: Composition-based stats.
Identities = 31/153 (20%), Positives = 61/153 (39%), Gaps = 15/153 (9%)
Query: 111 TWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWI 170
T+ DF + G+N +R+P + Q N P Q Q+ ++K+L A+ N + +
Sbjct: 48 TYPAASDFSYFAGKGMNTIRLPFLWERVQPELNGPLDQAQLGLIKKSLEAAKANKQYLIL 107
Query: 171 DLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNE 230
DLH SG R + ++ + ++ D + L+NE
Sbjct: 108 DLHNYATY------SGKRIGTS---DVPAGALADLWRRLALEFKD----DKAVIFGLMNE 154
Query: 231 PLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVII 263
P G ++ ++R+TG+ +++
Sbjct: 155 PNG--ISAPDWANAAQGTITAIRKTGAKNLILV 185
>4U5I-A nrPDB
Length = 403
Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats.
Identities = 35/174 (20%), Positives = 64/174 (36%), Gaps = 29/174 (16%)
Query: 109 WSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWARKNNI 166
WS E F G VRIP+ W + PY + + +E+ + W+
Sbjct: 103 WSKSAMEYYFDDFKAAGYKNVRIPV-RWDNHTMRTYPYTIDKAFLDRVEQVVDWSLSRGF 161
Query: 167 RVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIE 226
I+ H + ++ N + + I +++ + + E
Sbjct: 162 VTIINSHHDDWIKEDYN-------------GNIERFEKIWEQIAERFKNKSEN---LLFE 205
Query: 227 LLNEPLGPVLN--MDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT 278
++NEP G + + +D + L +R+T VII GYWN++ T
Sbjct: 206 IMNEPFGNITDEQIDDMNSRIL---KIIRKTNPTRIVIIGG-----GYWNSYNT 251
>4M24-A nrPDB
Length = 321
Score = 49.6 bits (117), Expect = 3e-06, Method: Composition-based stats.
Identities = 35/187 (18%), Positives = 71/187 (37%), Gaps = 19/187 (10%)
Query: 112 WITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWID 171
+ E F+ S G++ VR P+ + Q N ++ L A++N+I+V +D
Sbjct: 29 FPPEGYFEYWSEQGIHTVRFPLKWERLQPSLNAELDDVYASLVDDMLDQAKENDIKVILD 88
Query: 172 LHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
+H + + +++ I K++ G D + +++NEP
Sbjct: 89 VHNYARYRKKVIGT---------EDVPVSAYQDLMERIAKRWQG---HDALFAYDIMNEP 136
Query: 232 LGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIH-----DAFQVFGYWNNFLTVAEGQWNV 286
G + G + +R+ P++I A + Y + L + + N+
Sbjct: 137 YGSADKL--WPAAAQAGIDGVRKYDKKRPLLIEGASWSSAARWPRYADELLKLKDPADNM 194
Query: 287 VVDHHHY 293
V H Y
Sbjct: 195 VFSAHVY 201
>4LX4-A nrPDB
Length = 330
Score = 48.1 bits (113), Expect = 7e-06, Method: Composition-based stats.
Identities = 42/211 (19%), Positives = 83/211 (39%), Gaps = 27/211 (12%)
Query: 112 WITEQD-FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWI 170
+ E+ FK ++ G+ +R P + Q + Q++ L+K L A +N +V +
Sbjct: 37 FYPEKKHFKYYADQGIRLIRFPFIWERVQHSLDSGLNFDQIRLLKKTLDLAAQNGQKVIL 96
Query: 171 DLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNE 230
D+H S + +V + +++ G ++G +++NE
Sbjct: 97 DMHNYGRYHGELIGSSKVPY---------EAYASVWRKLAERFKG---HPGLLGYDIMNE 144
Query: 231 PLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIH-DAFQVFGYW----NNFLTVAEGQWN 285
P V +++R+ T + I + + +W NFL + +
Sbjct: 145 PHSTV---GLWPGAAQAAVDAIREVDDQTLIFIEGERWSSAYHWPLVNANFL-INDPADR 200
Query: 286 VVVDHHHY--QVFSG---GELSRNINDHISV 311
++ + H Y FSG + SRNI+ I V
Sbjct: 201 LIYEAHLYFDDDFSGKYMAQTSRNIDPMIGV 231
>4YZP-A nrPDB
Length = 536
Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats.
Identities = 34/157 (21%), Positives = 60/157 (38%), Gaps = 21/157 (13%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWA-FQLLDNDPYVQGQVQYLEKALGWARKNNIRVWID 171
+ E F I + G VRIP+ + + P + +E+ WA + V ++
Sbjct: 55 VREHTFDDIRDAGFKSVRIPVTWDSHIGSAPEYPIDTDWMNRVEEVTDWALEREFYVVLN 114
Query: 172 LHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLN----VLNTIFKKYGGNEYSDVVIGIEL 227
+H +S L S G++ Q TL+ V I +++ + E+
Sbjct: 115 IHH---------DSWLWISRM---GNSQQETLDKLGKVWKQIAERFKNKSER---LLFEI 159
Query: 228 LNEPLG-PVLNMDKLKQFFLDGYNSLRQTGSVTPVII 263
+NEP G M+ L + L+ S VI+
Sbjct: 160 VNEPTGMSAYQMNLLNREMLNIIRSTGGKNGQRLVIV 196
>4W8B-A nrPDB
Length = 386
Score = 41.9 bits (97), Expect = 5e-04, Method: Composition-based stats.
Identities = 34/203 (16%), Positives = 67/203 (33%), Gaps = 26/203 (12%)
Query: 111 TWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWI 170
T T+Q + G VRIP W N + +++ + + + I V +
Sbjct: 36 TLTTQQIIDAVKAAGFKSVRIPCS-WDIHSDSNGEIDAQWMARVKQVVNYCINDGIYVVL 94
Query: 171 DLHGAPGSQNGFDNSGLRDSYNFQNG----DNTQVTLNVLNTIFKKYGGNEYSDVVIGIE 226
+ H G S SY + ++ I ++ + + G
Sbjct: 95 NDHWDNGWIEVLGFSKSSSSYQAVDEATITSKITRLKDLWTQIANEFKDYDEHLLFAG-- 152
Query: 227 LLNEP-------------LGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYW 273
LNEP L P+L + Q F++ + + +++
Sbjct: 153 -LNEPFQEYSLFSGHHEELTPIL--CRYNQAFVEAVRATGGNNAQRTLVVQGPSTNINSS 209
Query: 274 NNFLTVA---EGQWNVVVDHHHY 293
N++T E ++V+ H+Y
Sbjct: 210 VNYMTADKLPETAGRLMVEVHYY 232
>4NF7-A nrPDB
Length = 363
Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats.
Identities = 20/118 (16%), Positives = 47/118 (39%), Gaps = 8/118 (6%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLH 173
T+ +++ G N +RIP+ + + + + +++ + + N++ V ++ H
Sbjct: 50 TKALIDEVAKAGFNTIRIPVSWGQYTSGSDYQIPDFVMNRVKEVVDYCIVNDMYVILNSH 109
Query: 174 GAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
S F N + + ++ I K++ +Y V E +NEP
Sbjct: 110 HDINSDYCF-----YVPNNANKDRSEKYFKSIWTQIAKEFRNYDYHLV---FETMNEP 159
>3WFL-A nrPDB
Length = 342
Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats.
Identities = 28/139 (20%), Positives = 51/139 (36%), Gaps = 17/139 (12%)
Query: 138 FQLLDNDPYV----QGQVQYLEKALGWARKNNIRV-------WIDLHGAPGSQNGFDNSG 186
FQLL + ++ L+ + A ++N+++ W D G P N F S
Sbjct: 71 FQLLQDGTATINTGSDGLERLDYVVSSAEQHNVKLIINFVNNWSDYGGIPAYVNAFGGST 130
Query: 187 LRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLGPVLNMDKLKQFFL 246
+ + + + N + T+ +Y S V EL NEP + + +
Sbjct: 131 ---TSWYTDEASQAAYRNYIKTVVSRYID---SPAVFAWELANEPRCHGCDTSVIYNWVA 184
Query: 247 DGYNSLRQTGSVTPVIIHD 265
+ ++ S V I D
Sbjct: 185 ATSSFIKSIDSQHLVCIGD 203
>5H4R-A nrPDB
Length = 396
Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats.
Identities = 29/158 (18%), Positives = 64/158 (40%), Gaps = 25/158 (15%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLH 173
T+Q + G N +RIP+ + N + + +++ + +A KN + V I++H
Sbjct: 82 TKQMIDTVKKAGFNTIRIPVSWHNHVTGSNFTISKRWLDRVQQVVDYAMKNKMYVIINIH 141
Query: 174 GAPGSQNGFDNSGLRDSYNFQNGDNTQVTL----NVLNTIFKKYGGNEYSDVVIGIELLN 229
+ Y + N + Q ++ ++ + ++ Y+D +I E +N
Sbjct: 142 H-----------DIMPGYYYPNSQHLQTSIKYVKSIWTQVATRFKN--YNDHLI-FEAVN 187
Query: 230 EP------LGPVLNMDKLK-QFFLDGYNSLRQTGSVTP 260
+P L+M+ + + ++ N L Q T
Sbjct: 188 QPRLTGSRFEWWLDMNNPECRDAVEAINKLNQVFVDTV 225
>2OYK-A nrPDB
Length = 481
Score = 37.7 bits (86), Expect = 0.009, Method: Composition-based stats.
Identities = 39/207 (18%), Positives = 70/207 (33%), Gaps = 66/207 (31%)
Query: 113 ITEQDFK-QISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKA---LGWARKNNIRV 168
TE D + +++G NFVR I + + ++ P V Q QYL++ +GW + +V
Sbjct: 66 FTEADLAREYADMGTNFVRFLISW---RSVEPAPGVYDQ-QYLDRVEDRVGWYAERGYKV 121
Query: 169 WIDLHG-----------------------------------------------APGSQNG 181
+D+H PG
Sbjct: 122 MLDMHQDVYSGAITPEGNSGNGAGAIGNGAPAWATYMDGLPVEPQPRWELYYIQPGVMRA 181
Query: 182 FDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPL-----GPVL 236
FDN + ++ + + + ++ N D V+ +L+NEP GP
Sbjct: 182 FDN---FWNTTGKHPELVEHYAKAWRAVADRFADN---DAVVAYDLMNEPFGGSLQGPAF 235
Query: 237 NMDKLKQFFLDGYNSLRQTGSVTPVII 263
L + +++RQ T V +
Sbjct: 236 EAGPLAAMYQRTTDAIRQVDQDTWVCV 262
>1EDG-A nrPDB
Length = 380
Score = 37.7 bits (86), Expect = 0.010, Method: Composition-based stats.
Identities = 24/152 (15%), Positives = 52/152 (34%), Gaps = 15/152 (9%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLH 173
T+Q I G N VRIP+ + + + +++ + + N + V ++ H
Sbjct: 63 TKQMIDAIKQKGFNTVRIPVSWHPHVSGSDYKISDVWMNRVQEVVNYCIDNKMYVILNTH 122
Query: 174 GAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLG 233
G+ S + + + +V I ++ + + E +NEP
Sbjct: 123 HDVDKVKGYFPSSQYMA------SSKKYITSVWAQIAARFANYDEHLI---FEGMNEP-R 172
Query: 234 PVLNMDKL-----KQFFLDGYNSLRQTGSVTP 260
V + ++ +D N + Q
Sbjct: 173 LVGHANEWWPELTNSDVVDSINCINQLNQDFV 204
>4IM4-A nrPDB
Length = 336
Score = 37.7 bits (86), Expect = 0.011, Method: Composition-based stats.
Identities = 30/155 (19%), Positives = 63/155 (40%), Gaps = 25/155 (16%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWARKNNIRVWID 171
T+ +++ +G N VR+P+ W + Y + + +E+ + + + I+
Sbjct: 38 TKAMIEKVREMGFNAVRVPVT-WDTHIGPAPDYKIDEAWLNRVEEVVNYVLDCGMYAIIN 96
Query: 172 LHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
LH DN+ + +Y + ++ + V I ++ + D + E +NEP
Sbjct: 97 LHH--------DNTWIIPTYANEQRSKEKL-VKVWEQIATRF---KDYDDHLLFETMNEP 144
Query: 232 L----------GPVLNMDKLKQFFLDGYNSLRQTG 256
G N D + +F L N++R +G
Sbjct: 145 REVGSPMEWMGGTYENRDVINRFNLAVVNTIRASG 179
>5D8Z-A nrPDB
Length = 347
Score = 37.3 bits (85), Expect = 0.014, Method: Composition-based stats.
Identities = 31/173 (17%), Positives = 59/173 (34%), Gaps = 30/173 (17%)
Query: 93 TQTLGKEAASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLD--NDPYVQGQ 150
TQ G + A ++ KH+ + + G N R+P+G W F +
Sbjct: 52 TQYYGADGAGQM--KHF-----------VDDDGFNVFRLPVG-WQFITDGVAGGDIDEDN 97
Query: 151 VQYLEKALGWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIF 210
+ + +D+H G G Q + ++I
Sbjct: 98 WAEYDALVQACLDAGASCIVDVHNYARFNGEIIGQG---------GPTNQDFAALWSSIA 148
Query: 211 KKYGGNEYSDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVII 263
KY N+ I ++NEP V +++ ++RQ G+ + +I+
Sbjct: 149 AKYADNDK----IIFGVMNEP-HDVPDINLWADSVQAAVTAIRQAGATSQIIL 196
>5E0C-A nrPDB
Length = 537
Score = 36.9 bits (84), Expect = 0.017, Method: Composition-based stats.
Identities = 23/123 (18%), Positives = 50/123 (40%), Gaps = 18/123 (14%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYV--QGQVQYLEKALGWARKNNIRVWI 170
+T + K I++ G +RIP+ W Q+ + Y + +E+ + WA + ++ V +
Sbjct: 42 VTRELIKTIADEGYKSIRIPVT-WENQMGNAPDYTINEDFFSRVEQVIDWALEEDLYVML 100
Query: 171 DLHGAPGSQNGFDNSGLRDSYNFQN--GDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELL 228
+LH YN ++ + + + +++ G + E +
Sbjct: 101 NLHH----------DSWLWIYNMEHNYDEVMAKYTALWEQLSERFQG---HSHKLMFESV 147
Query: 229 NEP 231
NEP
Sbjct: 148 NEP 150
>3NDZ-A nrPDB
Length = 345
Score = 36.9 bits (84), Expect = 0.019, Method: Composition-based stats.
Identities = 36/152 (23%), Positives = 62/152 (40%), Gaps = 27/152 (17%)
Query: 118 FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWARKNNIRVWIDLHGA 175
+I G N +R+P+ W + Y Q ++ +E+ +A N++ V I+LH
Sbjct: 48 INKIKEAGFNTLRLPVT-WDGHMGAAPEYTIDQTWMKRVEEIANYAFDNDMYVIINLHH- 105
Query: 176 PGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLGPV 235
+N L+ Y + Q+T V I + +Y D +I E +NEP PV
Sbjct: 106 -------ENEWLKPFYANEAQVKAQLT-KVWTQIANNF--KKYGDHLI-FETMNEP-RPV 153
Query: 236 LNMDKL-----------KQFFLDGYNSLRQTG 256
+ ++ L N++R TG
Sbjct: 154 GASLQWTGGSYENREVVNRYNLTAVNAIRATG 185
>6GL0-A nrPDB
Length = 331
Score = 35.0 bits (79), Expect = 0.061, Method: Composition-based stats.
Identities = 43/197 (21%), Positives = 79/197 (40%), Gaps = 31/197 (15%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYV--QGQVQYLEKALGWARKNNIRVWID 171
T+ +I+ +G +R+P+ W F + + Y+ + +E +A +N + V I+
Sbjct: 41 TKAMIDEIAKMGFKTLRLPVT-WKFHIGEGPDYLIEANWLDKVEAIANFALENEMYVIIN 99
Query: 172 LHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
+H D + + +Y + +++ V I ++ Y D +I E LNEP
Sbjct: 100 IHH--------DETWILPTYEKADEVKDELS-KVWTQIANRF--KTYGDYLI-FETLNEP 147
Query: 232 L----------GPVLNMDKLKQFFLDGYNSLRQTGSV-----TPVIIHDAFQVFGYWNNF 276
G D + Q+ +++R TG V + A N++
Sbjct: 148 RHKGTPEEWKGGTQEGRDAVNQYHQVSVDAIRATGGNNAKRKIMVSTYAASTASNALNDY 207
Query: 277 LTVAEGQWNVVVDHHHY 293
L V G NV+V H Y
Sbjct: 208 L-VPNGDKNVIVSVHSY 223
>1WKY-A nrPDB
Length = 464
Score = 35.0 bits (79), Expect = 0.063, Method: Composition-based stats.
Identities = 64/321 (19%), Positives = 105/321 (32%), Gaps = 92/321 (28%)
Query: 108 HWSTWITEQD---FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKN 164
H W +Q + I+N G N VRI + D + + +Q + + A N
Sbjct: 32 HGHAWYKDQATTAIEGIANTGANTVRIVLS-------DGGQWTKDDIQTVRNLISLAEDN 84
Query: 165 NIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIG 224
N+ +++H A G DS N ++ + G E D VI
Sbjct: 85 NLVAVLEVHDATGY----------DSIASLN-----RAVDYWIEMRSALIGKE--DTVI- 126
Query: 225 IELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAF-----QVFGYWNNFLTV 279
I + NE G + + LR G ++I A Q + +
Sbjct: 127 INIANEWFG-SWDGAAWADGYKQAIPRLRNAGLNNTLMIDAAGWGQFPQSIHDYGREVFN 185
Query: 280 AEGQWNVVVDHHHYQVFSGG---ELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALT 336
A+ Q N + H Y+ ++GG ++ NI+ + V GE+
Sbjct: 186 ADPQRNTMFSIHMYE-YAGGNASQVRTNIDR-----------VLNQDLALVIGEF----- 228
Query: 337 DCAKWLNGVNRGARYEGAYDNAPYIGSCQPMLDISQWSDEHKTDTRRYIEAQLDAFEYTG 396
G R+ + I S +S++
Sbjct: 229 -----------GHRHTNGDVDESTIMS---------YSEQRGV----------------- 251
Query: 397 GWVFWSWKTENAPEWSFQTLT 417
GW+ WSWK N PEW + L+
Sbjct: 252 GWLAWSWKG-NGPEWEYLDLS 271
>1UR0-A nrPDB
Length = 399
Score = 34.2 bits (77), Expect = 0.10, Method: Composition-based stats.
Identities = 46/195 (23%), Positives = 73/195 (37%), Gaps = 31/195 (15%)
Query: 118 FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQY------LEKALGWARK---NNIRV 168
FK + G+N+VR+ I W NDPY Y LEKA+ ++ N +++
Sbjct: 54 FKTLKEAGVNYVRVRI--W------NDPYDANGNGYGGGNNDLEKAIQIGKRATANGMKL 105
Query: 169 WIDLHGAPGSQNGFDNSGLRD--SYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIE 226
D H + + + + NF++ + K G + V +G E
Sbjct: 106 LADFHYSDFWADPAKQKAPKAWANLNFEDKKTALYQYTKQSLKAMKAAGIDIGMVQVGNE 165
Query: 227 LLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLTVAEGQWNV 286
N L + K+ Q F G ++R+T S V +H + N T W
Sbjct: 166 -TNGGLAGETDWAKMSQLFNAGSQAVRETDSNILVALH--------FTNPETSGRYAWIA 216
Query: 287 VVDHHH---YQVFSG 298
H H Y VF+
Sbjct: 217 ETLHRHHVDYDVFAS 231
>1ECE-A nrPDB
Length = 358
Score = 33.8 bits (76), Expect = 0.16, Method: Composition-based stats.
Identities = 44/206 (21%), Positives = 84/206 (40%), Gaps = 29/206 (14%)
Query: 118 FKQISNLGLNFVRIPIGYWA-----------FQLLDNDPYVQGQVQYLEKALGWARKNNI 166
QI +LG N +R+P F ++ D +Q ++K + +A + +
Sbjct: 50 LDQIKSLGYNTIRLPYSDDILKPGTMPNSINFYQMNQDLQGLTSLQVMDKIVAYAGQIGL 109
Query: 167 RVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIE 226
R+ +D H D SG + + + + + ++ L + ++Y GN V+G +
Sbjct: 110 RIILDRHRP-------DCSG-QSALWYTSSVSEATWISDLQALAQRYKGN---PTVVGFD 158
Query: 227 LLNEPLGPVL--NMDKLKQFFLDGYNSLRQTGSVTP--VIIHDAFQVFG---YWNNFLTV 279
L NEP P D + L + SV P +I + Q + YW
Sbjct: 159 LHNEPHDPACWGCGDPSIDWRLAAERAGNAVLSVNPNLLIFVEGVQSYNGDSYWWGGNLQ 218
Query: 280 AEGQWNVVVDHHHYQVFSGGELSRNI 305
GQ+ VV++ + V+S + + ++
Sbjct: 219 GAGQYPVVLNVPNRLVYSAHDYATSV 244
>2JEP-A nrPDB
Length = 395
Score = 33.4 bits (75), Expect = 0.17, Method: Composition-based stats.
Identities = 50/242 (20%), Positives = 96/242 (39%), Gaps = 34/242 (14%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYW-AFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWID 171
+T + K++ G +RIP+ Y N + +++ + +A + V I+
Sbjct: 70 VTPELIKKVKAAGFKSIRIPVSYLNNIGSAPNYTINAAWLNRIQQVVDYAYNEGLYVIIN 129
Query: 172 LHGAPGSQNGFDNSGLRDSYNFQNGDNT----QVTLNVLNTIFKKYGGNEYSDVVIGIEL 227
+HG +G+++ ++ + NG N + V I K+ Y+D +I E
Sbjct: 130 IHG-----DGYNS--VQGGWLLVNGGNQTAIKEKYKKVWQQIATKFSN--YNDRLI-FES 179
Query: 228 LNEPLGP---------VLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLT 278
+NE N++ Q F+D ++RQTG + + + WN +
Sbjct: 180 MNEVFDGNYGNPNSAYYTNLNAYNQIFVD---TVRQTGGNN----NARWLLVPGWNTNID 232
Query: 279 VAEGQWNVVVDHHHYQVFSGGELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDC 338
G + + +Y+ + + I IS WD E + N+ +W A T+
Sbjct: 233 YTVGNYGFTLPTDNYRSSAIPSSQKRI--MISAHYYSPWDFAGEENGNIT-QWGATSTNP 289
Query: 339 AK 340
AK
Sbjct: 290 AK 291
>4HU0-A nrPDB
Length = 359
Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats.
Identities = 28/122 (22%), Positives = 53/122 (43%), Gaps = 20/122 (16%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDL 172
+++ F+ I + G N VR+P+ A++ + V+G ++ L++ + W + I +D
Sbjct: 86 FSKKHFEVIRSWGANVVRVPVHPRAWK----ERGVKGYLELLDQVVAWNNELGIYTILDW 141
Query: 173 HGAPGSQNGFDNSGLRDSYNFQNGD---NTQVTLNVLNTIFKKYGGNEYSDVVIGIELLN 229
H + G S FQN T + + ++Y G + V E+ N
Sbjct: 142 H----------SIGNLKSEMFQNNSYHTTKGETFDFWRRVSERYNG---INSVAFYEIFN 188
Query: 230 EP 231
EP
Sbjct: 189 EP 190
>5A94-A nrPDB
Length = 365
Score = 33.1 bits (74), Expect = 0.29, Method: Composition-based stats.
Identities = 27/118 (22%), Positives = 52/118 (44%), Gaps = 21/118 (17%)
Query: 118 FKQISNL-GLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHGAP 176
F++++N G+N +R+PI +++ L D Y + ++++A+ WA I + +D H
Sbjct: 90 FEELANNWGVNTIRLPIHPVSWRKLGPDVY----LGHIDEAVRWANDLGIYLILDWH--- 142
Query: 177 GSQNGFDNSGLRDSYNFQNG---DNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEP 231
+ G + +Q+ + T + I +Y V EL NEP
Sbjct: 143 -------SIGYLPTEQYQHPMYDTTIKETRDFWRRITFRYQN---VPTVAVYELFNEP 190
>4V2X-A nrPDB
Length = 597
Score = 32.3 bits (72), Expect = 0.39, Method: Composition-based stats.
Identities = 15/64 (23%), Positives = 33/64 (51%), Gaps = 3/64 (4%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQ--VQYLEKALGWARKNNIRVWI 170
+T + +QI++ G +RIP+ W ++ Y + +++ + WA + ++ V I
Sbjct: 90 VTRELIEQIADEGYKSIRIPVT-WENRIGGAPDYPIDPQFLNRVDQVVQWALEEDLYVMI 148
Query: 171 DLHG 174
+LH
Sbjct: 149 NLHH 152
>1PBG-A nrPDB
Length = 468
Score = 32.3 bits (72), Expect = 0.45, Method: Composition-based stats.
Identities = 26/136 (19%), Positives = 49/136 (36%), Gaps = 15/136 (11%)
Query: 117 DFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHGAP 176
D + G+N +RI I + + V++ K K ++ ++ LH
Sbjct: 59 DLELAEEYGVNGIRISIAWSRIFPTGYGEVNEKGVEFYHKLFAECHKRHVEPFVTLHH-- 116
Query: 177 GSQNGFDN-SGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLGPV 235
FD L + +F N +N + ++ F+++ Y NE +GP+
Sbjct: 117 -----FDTPEALHSNGDFLNRENIEHFIDYAAFCFEEFPEVNY------WTTFNE-IGPI 164
Query: 236 LNMDKLKQFFLDGYNS 251
+ L F G
Sbjct: 165 GDGQYLVGKFPPGIKY 180
>6A8M-A nrPDB
Length = 461
Score = 31.9 bits (71), Expect = 0.50, Method: Composition-based stats.
Identities = 19/76 (25%), Positives = 32/76 (42%), Gaps = 9/76 (11%)
Query: 216 NEYSDVVIGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNN 275
N+ + IEL P N+ + F D +R+ GS + D++Q
Sbjct: 93 NKKLENTFKIELWQSSKEPGHNL----KLFEDLVERVREAGSAVGLATKDSYQ-----GK 143
Query: 276 FLTVAEGQWNVVVDHH 291
F+T +G W+ V+ H
Sbjct: 144 FITEWKGVWDTAVEKH 159
>6HA9-A nrPDB
Length = 396
Score = 31.5 bits (70), Expect = 0.81, Method: Composition-based stats.
Identities = 22/144 (15%), Positives = 53/144 (36%), Gaps = 9/144 (6%)
Query: 113 ITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDL 172
++ + K + + G + VRIP+ + + ++ + +++ + A N + V I++
Sbjct: 76 VSNELLKLVKDSGFDAVRIPVAWDQYANQESAEISAAWLNRVKQVVQMAIDNELYVLINI 135
Query: 173 HGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPL 232
H G+ + + + +N + I + + G N
Sbjct: 136 H----WDGGWLENNITPAKKDENNAKQKAF---WEQIATHLRDFDEHLLFAGTNAPNA-- 186
Query: 233 GPVLNMDKLKQFFLDGYNSLRQTG 256
MD L + +++R TG
Sbjct: 187 ENAEQMDVLNSYLQTFVDAVRSTG 210
>3ZMR-A nrPDB
Length = 475
Score = 31.1 bits (69), Expect = 1.0, Method: Composition-based stats.
Identities = 19/65 (29%), Positives = 29/65 (44%), Gaps = 3/65 (4%)
Query: 118 FKQISNLGLNFVRIPIGYWAFQLLDNDPY--VQGQVQYLEKALGWARKNNIRVWIDLHGA 175
F+ I G + VRIP+ Y + Q D Y + +E A+ A + V I++H
Sbjct: 160 FEGIKAAGFDVVRIPVAY-SHQFEDAATYKIKSAWMDKVEAAVKAALDAGLYVIINIHWE 218
Query: 176 PGSQN 180
G N
Sbjct: 219 GGWLN 223
>4YHG-A nrPDB
Length = 389
Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats.
Identities = 24/125 (19%), Positives = 48/125 (38%), Gaps = 13/125 (10%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYV--QGQVQYLEKALGWARKNNIRVWID 171
T+Q F ++ G VRIP+ W + + Y +G + +++ + A K + V I+
Sbjct: 43 TQQTFNGLAKAGFRSVRIPVT-WMGHIGNAPTYAIERGWLDRVDELVHMAHKAGLIVIIN 101
Query: 172 LHGAPGSQNGFDNSG-----LRDSYNFQNGDNT--QVTLNVLNTIFKKYGGNEYSDVVIG 224
+H + G L + + + Q + I K++ + +
Sbjct: 102 IHHDGFGAADTPSKGSHWLDLPAAVASEERNQLIKQELTMIWLQIGKRFANDGE---WLV 158
Query: 225 IELLN 229
E LN
Sbjct: 159 FETLN 163
>3JUG-A nrPDB
Length = 345
Score = 30.8 bits (68), Expect = 1.3, Method: Composition-based stats.
Identities = 59/321 (18%), Positives = 100/321 (31%), Gaps = 92/321 (28%)
Query: 108 HWSTWITEQD---FKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKN 164
H W + I+ G N +RI + D + + + + + + A +N
Sbjct: 47 HGHAWYKDTASTAIPAIAEQGANTIRIVLS-------DGGQWEKDDIDTVREVIELAEQN 99
Query: 165 NIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIG 224
+ +++H A G RDS + ++ + G E D VI
Sbjct: 100 KMVAVVEVHDATG----------RDSR-----SDLDRAVDYWIEMKDALIGKE--DTVI- 141
Query: 225 IELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAF------QVFGYWNNFLT 278
I + NE G + ++D LR G +++ A + Y +
Sbjct: 142 INIANEWYG-SWDGAAWADGYIDVIPKLRDAGLTHTLMVDAAGWGQYPQSIHDYGQDVFN 200
Query: 279 VAEGQWNVVVDHHHYQVFSGG--ELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALT 336
A+ N + H Y+ G + NI+ + V GE+ T
Sbjct: 201 -ADPLKNTIFSIHMYEYAGGDANTVRSNIDR-----------VIDQDLALVIGEFGHRHT 248
Query: 337 DCAKWLNGVNRGARYEGAYDNAPYIGSCQPMLDISQWSDEHKTDTRRYIEAQLDAFEYTG 396
D G D I +S+E T
Sbjct: 249 D---------------GDVDE----------DTILSYSEETGT----------------- 266
Query: 397 GWVFWSWKTENAPEWSFQTLT 417
GW+ WSWK N+ EW + L+
Sbjct: 267 GWLAWSWKG-NSAEWDYLDLS 286
>1BGG-A nrPDB
Length = 448
Score = 30.8 bits (68), Expect = 1.4, Method: Composition-based stats.
Identities = 18/105 (17%), Positives = 38/105 (36%), Gaps = 6/105 (5%)
Query: 115 EQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHG 174
E+D + + LG+ R + + + Q + Y + + N I + L+
Sbjct: 62 EEDIRLMKELGIRTYRFSVSWPRIFPNGDGEVNQEGLDYYHRVVDLLNDNGIEPFCTLYH 121
Query: 175 APGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYS 219
Q L+D+ + N Q + T+F+++ G
Sbjct: 122 WDLPQ------ALQDAGGWGNRRTIQAFVQFAETMFREFHGKIQH 160
>5WKA-A nrPDB
Length = 473
Score = 30.4 bits (67), Expect = 1.5, Method: Composition-based stats.
Identities = 12/68 (17%), Positives = 26/68 (38%), Gaps = 2/68 (2%)
Query: 107 KHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNI 166
H+ W E+D ++ LG+ R + + P Q + + ++ + R NI
Sbjct: 52 DHYHRW--EEDLDLLAELGVQAYRFSVAWPRIHPDVTGPANQKGLDFYQRLIDGLRDRNI 109
Query: 167 RVWIDLHG 174
++
Sbjct: 110 IPLPTMYH 117
>4W84-A nrPDB
Length = 340
Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats.
Identities = 21/121 (17%), Positives = 47/121 (38%), Gaps = 16/121 (13%)
Query: 114 TEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYV--QGQVQYLEKALGWARKNNIRVWID 171
T++ +++ G N +RIP+ + A L Y + +++ + +A + + + +D
Sbjct: 43 TQEIVDTVNDRGFNAIRIPVTF-ANHLGPAPEYTISADWLARVKEVVDYAVNDGMYIILD 101
Query: 172 LHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYG-GNEYSDVVIGIELLNE 230
H + + +N L I+K+ + D + E +NE
Sbjct: 102 THHETNY------------WLKTDPNNEAALCEELAAIWKQLAEAFKDYDEKLMFEGMNE 149
Query: 231 P 231
P
Sbjct: 150 P 150
>5IG4-A nrPDB
Length = 145
Score = 30.4 bits (67), Expect = 1.6, Method: Composition-based stats.
Identities = 13/36 (36%), Positives = 23/36 (63%), Gaps = 2/36 (5%)
Query: 63 VLEPYMTPSLFEPFQNGNDQSGVPVDEYHWTQTLGK 98
+++P++T FEPF NGN G+ ++++ TL K
Sbjct: 43 LVDPHVT--CFEPFSNGNLVEGLEFHKFYFDNTLSK 76
>4XZW-A nrPDB
Length = 313
Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats.
Identities = 39/203 (19%), Positives = 75/203 (36%), Gaps = 29/203 (14%)
Query: 204 NVLNTIFKKYGGN---EYSDVV-IGIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVT 259
N+ K++ EY + + E+ NEP G V +K++ + + ++R
Sbjct: 112 NLYKEQAKRFFAEMAREYGNTPNVIYEIANEPNGDVTWEEKIRPYADEVIRTIRSIDRDN 171
Query: 260 PVIIHDAFQVFGYW----NNFLTVAEGQWNVVVDHHHYQVFSGGELSRNINDHIS----- 310
+I+ G W ++ + N++ H Y G L N +S
Sbjct: 172 LIIVGT-----GTWSQDVDDVASDPLPYKNIMYALHFYAGTHGQFLRDKANYALSKGTPI 226
Query: 311 VACNWGWDAKKESHWNVAGEWSAALTDCAKWLNGVNRGARYEGAY---DNAPYIGSCQPM 367
WG + +G+ L +WL ++ + D + +P
Sbjct: 227 FVTEWGTS-------DASGDGGVFLDQSREWLKYLDSKTISWVNWSLCDKNEASAALRPG 279
Query: 368 LDI-SQWSDEHKTDTRRYIEAQL 389
D W D+H +D+ R+I+A+L
Sbjct: 280 ADPHGGWGDDHLSDSGRFIKAKL 302
>3MAN-A nrPDB
Length = 302
Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats.
Identities = 38/213 (17%), Positives = 66/213 (30%), Gaps = 35/213 (16%)
Query: 107 KHWSTWITE--QDFKQISNLGLNFVRIPIGYWAFQLLDND-PYVQGQVQYLEKALGWARK 163
H W + Q F I + G N VR+ +L N + + + + ++
Sbjct: 25 SHPHNWYPQHTQAFADIKSHGANTVRV--------VLSNGVRWSKNGPSDVANVISLCKQ 76
Query: 164 NNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVI 223
N + +++H G S L + ++ + G E +
Sbjct: 77 NRLICMLEVHDTTGYGEQSGASTLDQA------------VDYWIELKSVLQGEEDY---V 121
Query: 224 GIELLNEPLG-PVLNMDKLKQFFLDGYNSLRQTGSVTPVIIHDAFQVFGYWNNFLTVAEG 282
I + NEP G + LR G +++ DA W N +
Sbjct: 122 LINIGNEPYGNDSATVAAWATDTSAAIQRLRAAGFEHTLVV-DAPNWGQDWTNTMRNNAD 180
Query: 283 Q-------WNVVVDHHHYQVFSGGELSRNINDH 308
Q N V H Y V+S + +H
Sbjct: 181 QVYASDPTGNTVFSIHMYGVYSQASTITSYLEH 213
>4XZB-A nrPDB
Length = 314
Score = 29.6 bits (65), Expect = 3.1, Method: Composition-based stats.
Identities = 42/208 (20%), Positives = 83/208 (39%), Gaps = 38/208 (18%)
Query: 204 NVLNTIFKKYGGN------EYSDVVIGIELLNEPLG-PVLNMDKLKQFFLDGYNSLRQTG 256
N+ K++ +Y +V+ E+ NEP G V +K++ + + ++R
Sbjct: 112 NLYKEQAKRFFAEMAREYGKYPNVI--YEIANEPNGNDVTWEEKIRPYADEVIRTIRSID 169
Query: 257 SVTPVIIHDAFQVFGYW----NNFLTVAEGQWNVVVDHHHYQVFSGGELSRNINDHISVA 312
+I+ G W ++ + N++ H Y G ++ + D + A
Sbjct: 170 RDNLIIVGT-----GTWSQDVDDVASDPLPYKNIMYAVHFY----SGTHTQWLRDRVDAA 220
Query: 313 CNWGWDAKKESHW---NVAGEWSAALTDCAKWLNGVN-RGARYEGAYDNAPYI------G 362
G S W + +G+ L + KW+ +N RG ++ N
Sbjct: 221 LQAGTPVF-VSEWGTSDASGDGGPYLEEAEKWIEFLNERGI----SWVNWSLCDKNEASA 275
Query: 363 SCQPMLDI-SQWSDEHKTDTRRYIEAQL 389
+ +P D W D+H +D+ R+I+A+L
Sbjct: 276 ALRPGADPHGGWGDDHLSDSGRFIKAKL 303
>4OEP-A nrPDB
Length = 107
Score = 29.2 bits (64), Expect = 3.2, Method: Composition-based stats.
Identities = 16/38 (42%), Positives = 23/38 (60%)
Query: 170 IDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLN 207
+ LH APG G SG RD+ +FQ+G+ + V +VL
Sbjct: 11 VTLHRAPGFGFGIAISGGRDNPHFQSGETSIVISDVLK 48
>5MZA-A nrPDB
Length = 488
Score = 29.2 bits (64), Expect = 3.3, Method: Composition-based stats.
Identities = 13/53 (24%), Positives = 23/53 (43%)
Query: 33 NLKFKRGGGHNVAWDYDNNVIRGVNLGGWFVLEPYMTPSLFEPFQNGNDQSGV 85
NL++ GGH + N I LG + Y + +++ ND+ G+
Sbjct: 120 NLEYLINGGHQAILNVKNGKINHSFLGDVLLAAKYQAQHTMKDYKSKNDKEGI 172
>4R27-A nrPDB
Length = 434
Score = 29.2 bits (64), Expect = 3.8, Method: Composition-based stats.
Identities = 10/59 (16%), Positives = 23/59 (38%), Gaps = 1/59 (1%)
Query: 116 QDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIRVWIDLHG 174
+D I+ LG R + WA + + + + ++ L R++ + + H
Sbjct: 58 EDIALIAGLGFTSYRFSVE-WARIEPEEGHFSVAALDHYKRVLEACREHGLTPVVTFHH 115
>3WE0-A nrPDB
Length = 580
Score = 29.2 bits (64), Expect = 3.9, Method: Composition-based stats.
Identities = 23/110 (20%), Positives = 38/110 (34%), Gaps = 19/110 (17%)
Query: 300 ELSRNINDHISVACNWGWDAKKESHWNVAGEWSAALTDCAKWLNGVN-------RGARYE 352
++R + ++V NWG ++A LT C WL +
Sbjct: 323 RIARASDGRLAVTDNWGD----------CRHYAAVLTTCQSWLLTTQIDCEESLFSQKMW 372
Query: 353 GAYDNAPYIGSCQP--MLDISQWSDEHKTDTRRYIEAQLDAFEYTGGWVF 400
A D Y+ S + M+D W D+ R + L G ++F
Sbjct: 373 MALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDRLTRGTYLF 422
>4TUF-A nrPDB
Length = 346
Score = 29.2 bits (64), Expect = 3.9, Method: Composition-based stats.
Identities = 37/164 (22%), Positives = 60/164 (36%), Gaps = 25/164 (15%)
Query: 81 DQSGVPVDEYHWTQTLGKEAASRILQKHWSTWITEQDFKQISNLGLNFVRIPIGYWAFQL 140
D SG V + G E + ++ W+ + Q+ LG N VR+P A
Sbjct: 11 DDSG-KVVQLKGVNVFGFETGNHVMHGLWARNWKDM-IVQMQGLGFNAVRLPF-CPATLR 67
Query: 141 LDNDPYVQG-----------QVQYLEKALGWARKNNIRVWIDLHGAPGSQNGFDNSGLRD 189
D P +Q L+K + + V +D H P D +G+ +
Sbjct: 68 SDTMPASIDYSRNADLQGLTSLQILDKVIAEFNARGMYVLLD-HHTP------DCAGISE 120
Query: 190 SYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLNEPLG 233
+ + L L + +Y Y V+G++L NEP G
Sbjct: 121 LW-YTGSYTEAQWLADLRFVANRYKNVPY---VLGLDLKNEPHG 160
>3QHO-A nrPDB
Length = 458
Score = 28.8 bits (63), Expect = 4.4, Method: Composition-based stats.
Identities = 26/122 (21%), Positives = 45/122 (36%), Gaps = 21/122 (17%)
Query: 120 QISNLGLNFVRIPIGYWAFQ----------LLDNDPYVQGQVQYLEKALGWARKNNIRVW 169
QI +LG N +R+P + + + D +Q +EK + A I V
Sbjct: 92 QIKSLGFNAIRLPFCTESVKPGTQPIGIDYSKNPDLRGLDSLQIMEKIIKKAGDLGIFVL 151
Query: 170 IDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVIGIELLN 229
+D H + + + + +N + K++G VIG +L N
Sbjct: 152 LDYHRI--------GCTHIEPLWYTEDFSEEDFINTWIEVAKRFG---KYWNVIGADLKN 200
Query: 230 EP 231
EP
Sbjct: 201 EP 202
>6ID0-C nrPDB
Length = 972
Score = 28.8 bits (63), Expect = 4.9, Method: Composition-based stats.
Identities = 12/40 (30%), Positives = 20/40 (50%)
Query: 266 AFQVFGYWNNFLTVAEGQWNVVVDHHHYQVFSGGELSRNI 305
A FG+ + T +GQ + HH+Q+ G L ++I
Sbjct: 877 AIDSFGFETDLRTHTQGQAFSLSVFHHWQIVPGDPLDKSI 916
>4MPS-A nrPDB
Length = 310
Score = 28.1 bits (61), Expect = 7.6, Method: Composition-based stats.
Identities = 26/124 (20%), Positives = 46/124 (37%), Gaps = 16/124 (12%)
Query: 159 GWARKNNIRVWIDLHGAPGSQNGFDNSGLRDSYNFQNGDNTQVTLNVLN----TIFKKYG 214
G + + + ID H A NG NFQ ++ T+ ++N T K++
Sbjct: 95 GSLKNSQLGREIDNHDAVLRFNGAPTD------NFQQDVGSKTTIRLMNSQLVTTEKRFL 148
Query: 215 GNEYSDVVIGIELLNEPLGPVLNMDKLKQ----FFLDGYNSLRQTGSVTPVIIHDAFQVF 270
+ GI ++ +P ++ K Q F + Y S R+ P I +
Sbjct: 149 KDSLYTE--GILIVWDPSVYHADIPKWYQKPDYNFFETYKSYRRLNPSQPFYILKPQMPW 206
Query: 271 GYWN 274
W+
Sbjct: 207 ELWD 210
>2VRK-A nrPDB
Length = 496
Score = 28.1 bits (61), Expect = 7.7, Method: Composition-based stats.
Identities = 13/38 (34%), Positives = 17/38 (44%), Gaps = 1/38 (2%)
Query: 84 GVPVDEYHWTQTLG-KEAASRILQKHWSTWITEQDFKQ 120
G DEYHW +G +E R++ HW I F
Sbjct: 73 GCFADEYHWKDGVGPREKRKRMVNTHWGGVIENNHFGT 110
>3K4D-A nrPDB
Length = 605
Score = 28.1 bits (61), Expect = 8.4, Method: Composition-based stats.
Identities = 27/158 (17%), Positives = 55/158 (34%), Gaps = 9/158 (5%)
Query: 108 HWSTWITEQDFKQISNLGLNFVRIPIGYWAFQLLDNDPYVQGQVQYLEKALGWARKNNIR 167
+++ + +D + G + V + + + + Y Y E+ L WA ++ I
Sbjct: 291 YFTGFGRHED-ADLRGKGFDNVLMVHDHALMDWIGANSYRTSHYPYAEEMLDWADEHGI- 348
Query: 168 VWIDLHGAPGSQN----GFDNSGLRDSYNFQNGDNTQVTLNVLNTIFKKYGGNEYSDVVI 223
V ID A G GF+ + N + L I + ++ V+
Sbjct: 349 VVIDETAAVGFNLSLGIGFEAGNKPKELYSEEAVNGETQQAHLQAIKELIARDKNHPSVV 408
Query: 224 GIELLNEPLGPVLNMDKLKQFFLDGYNSLRQTGSVTPV 261
+ NE P +++F + R+ P+
Sbjct: 409 MWSIANE---PDTRPQGAREYFAPLAEATRKLDPTRPI 443
Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta
Posted date: Jan 3, 2023 9:05 PM
Number of letters in database: 10,336,785
Number of sequences in database: 36,641
Lambda K H
0.315 0.139 0.429
Lambda K H
0.267 0.0425 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 20,662,239
Number of Sequences: 36641
Number of extensions: 952023
Number of successful extensions: 2245
Number of sequences better than 10.0: 59
Number of HSP's better than 10.0 without gapping: 24
Number of HSP's successfully gapped in prelim test: 67
Number of HSP's that attempted gapping in prelim test: 2180
Number of HSP's gapped (non-prelim): 107
length of query: 438
length of database: 10,336,785
effective HSP length: 100
effective length of query: 338
effective length of database: 6,672,685
effective search space: 2255367530
effective search space used: 2255367530
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 61 (28.1 bits)