BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P29622 (427 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6F02-A nrPDB 792 0.0 6F4U-A nrPDB 706 0.0 6EE5-A nrPDB 350 7e-97 2OL2-A nrPDB 348 2e-96 5HGC-A nrPDB 345 2e-95 6HGE-B nrPDB 333 1e-91 2VDY-A nrPDB 331 5e-91 3NE4-A nrPDB 324 4e-89 3DY0-A nrPDB 322 2e-88 1YXA-A nrPDB 317 6e-87 2XN5-A nrPDB 308 4e-84 1QMB-A nrPDB 293 1e-79 2V95-A nrPDB 271 5e-73 4Y40-A nrPDB 244 4e-65 1ATT-A nrPDB 184 5e-47 4EB1-I nrPDB 180 9e-46 5INW-A nrPDB 175 3e-44 4AJT-A nrPDB 165 4e-41 3LW2-A nrPDB 164 1e-40 1C5G-A nrPDB 163 1e-40 4GA7-A nrPDB 161 6e-40 4ZK0-A nrPDB 160 1e-39 3NDA-A nrPDB 160 1e-39 1JMJ-A nrPDB 159 2e-39 1HLE-A nrPDB 159 3e-39 1BY7-A nrPDB 157 1e-38 1UHG-A nrPDB 147 1e-35 2H4Q-A nrPDB 144 5e-35 4AJU-A nrPDB 144 9e-35 1IMV-A nrPDB 141 4e-34 4KDS-A nrPDB 139 2e-33 2H4P-A nrPDB 139 3e-33 3F02-A nrPDB 137 1e-32 4P0F-A nrPDB 127 9e-30 3LE2-A nrPDB 125 4e-29 5NCS-A nrPDB 123 1e-28 3ZHA-A nrPDB 119 3e-27 2R9Y-A nrPDB 118 4e-27 4DY0-A nrPDB 118 4e-27 1K9O-I nrPDB 117 8e-27 4DTE-A nrPDB 115 4e-26 1SEK-A nrPDB 115 4e-26 6CJ7-A nrPDB 112 3e-25 1C8O-A nrPDB 112 3e-25 1JJO-C nrPDB 109 2e-24 5NCU-A nrPDB 107 1e-23 1XQJ-A nrPDB 104 6e-23 1M93-B nrPDB 103 1e-22 3PZF-A nrPDB 103 1e-22 2OAY-A nrPDB 100 1e-21 2PEF-A nrPDB 95 7e-20 3OZQ-A nrPDB 92 3e-19 3STO-A nrPDB 81 9e-16 1SNG-A nrPDB 79 3e-15 6BJ5-B nrPDB 69 4e-12 1MTP-A nrPDB 60 1e-09 5M3Y-A nrPDB 54 2e-07 2WXZ-C nrPDB 52 5e-07 2WXX-A nrPDB 50 1e-06 5C98-A nrPDB 47 1e-05 3MI6-A nrPDB 30 1.7 3MOG-A nrPDB 30 2.1 4OR8-A nrPDB 29 3.0 1DGS-A nrPDB 29 3.7 1V9P-A nrPDB 29 4.0 3MWB-A nrPDB 28 6.6 5LZS-jj nrPDB 28 7.4 4ERD-A nrPDB 28 8.0 3ZTV-A nrPDB 28 8.1 4C0S-A nrPDB 28 8.3 >6F02-A nrPDB Length = 389 Score = 792 bits (2045), Expect = 0.0, Method: Compositional matrix adjust. Identities = 383/383 (100%), Positives = 383/383 (100%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 104 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG Sbjct: 1 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 60 Query: 105 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE Sbjct: 61 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 120 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 224 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI Sbjct: 121 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 180 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 284 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG Sbjct: 181 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 240 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK Sbjct: 241 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 300 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL Sbjct: 301 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 360 Query: 405 VVIFSTSTQSVLFLGKVVDPTKP 427 VVIFSTSTQSVLFLGKVVDPTKP Sbjct: 361 VVIFSTSTQSVLFLGKVVDPTKP 383 >6F4U-A nrPDB Length = 341 Score = 706 bits (1821), Expect = 0.0, Method: Compositional matrix adjust. Identities = 340/340 (100%), Positives = 340/340 (100%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 107 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF Sbjct: 2 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 61 Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL Sbjct: 62 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 121 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 227 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR Sbjct: 122 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 181 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 287 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR Sbjct: 182 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 241 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 347 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD Sbjct: 242 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 301 Query: 348 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 387 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF Sbjct: 302 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 341 >6EE5-A nrPDB Length = 379 Score = 350 bits (898), Expect = 7e-97, Method: Compositional matrix adjust. Identities = 189/380 (49%), Positives = 253/380 (66%), Gaps = 15/380 (3%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 104 + S K+A AN DFAF Y +A +P KNIFFSP+SIS+A AMLSLGA + +QILEG Sbjct: 15 AASSHKLAEANTDFAFSLYRELAKSSPDKNIFFSPVSISSALAMLSLGAKGDTHTQILEG 74 Query: 105 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 LGFN SE+D+H+GFQHLL TLN P GL+ + + LF+ +LK L FL D+ +Y+ Sbjct: 75 LGFN----SEADIHQGFQHLLQTLNRP-KGLQLKTANGLFVDKSLKLLDSFLEDSKKLYQ 129 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 224 A+ F +F D + IND V+K+T GKI DL+ +L D ++VLVN IYFK W+KPF Sbjct: 130 AEAFSVDF-DPEEAKKQINDWVEKQTNGKIKDLLKDLDSDTVLVLVNAIYFKGKWKKPFD 188 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 284 T +DF+VDE TTV+VPMM Q + ++Y HD L C VL + YKG+A++ ILP++G Sbjct: 189 PENTKEEDFHVDEKTTVKVPMMSQKGKFYYY-HDDELSCKVLELPYKGNASMLIILPDEG 247 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 ++ +E+ LTPE L +W L +R+ +EL+LPKF I G+Y L ++L LG TDLFS Sbjct: 248 GLQHLEQSLTPETLSKWLKSLTRRS----VELYLPKFKIEGTYDLKEVLSNLGITDLFSP 303 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404 ADLSGIT ++KL SK+ HKA L+V+E GTEAAAAT S + +RPFL Sbjct: 304 GADLSGIT-EEKLYVSKAVHKAVLEVNEEGTEAAAATFLEAIPMSIPPE---FKADRPFL 359 Query: 405 VVIFSTSTQSVLFLGKVVDP 424 +I T S+LF+GKVV+P Sbjct: 360 FLIRENKTGSILFMGKVVNP 379 >2OL2-A nrPDB Length = 395 Score = 348 bits (894), Expect = 2e-96, Method: Compositional matrix adjust. Identities = 178/375 (47%), Positives = 249/375 (66%), Gaps = 9/375 (2%) Query: 51 IAPANA-DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 +AP++ DF F Y +AS P +NIFFSP+SIS + AMLSLGA S ++ QILEGLG NL Sbjct: 29 VAPSSRRDFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNL 88 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 + SE ++HRGFQ LL LN P G + +G+ALF + F++ +Y A F Sbjct: 89 QKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFP 148 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 TNF D+ G ++ IND+V K+T+GKIVDL+ L + ++++VNYI+FKA WE F T Sbjct: 149 TNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQ 208 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289 +DFYV T VRVPMM ++ ++H YL DR L C V+ + Y+G+AT FILP++GKM+++ Sbjct: 209 EQDFYVTSETVVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQV 267 Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349 E L+ + L +W + +KR +LEL+LPKFSI GSY L+++LP LG +++F+ ADLS Sbjct: 268 ENGLSEKTLRKWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLS 323 Query: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFS 409 GI+ ++ S+ HKA ++VDE+GT AAAAT F SA+ N L FNRPFL+ I Sbjct: 324 GISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVD 383 Query: 410 TSTQSVLFLGKVVDP 424 ++LFLGKV P Sbjct: 384 N---NILFLGKVNRP 395 >5HGC-A nrPDB Length = 380 Score = 345 bits (885), Expect = 2e-95, Method: Compositional matrix adjust. Identities = 175/383 (45%), Positives = 254/383 (66%), Gaps = 8/383 (2%) Query: 43 GEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQIL 102 E +LK+ P NADFAF+F+ + E P KNIF+SP+SIS A+AML+LGA S ++SQIL Sbjct: 3 AEAMAALKLVPNNADFAFQFFREVTQEAPNKNIFYSPVSISTAFAMLALGARSATQSQIL 62 Query: 103 EGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAV 162 EGL FNLTE+ E ++H GF +L+H LN P G++ + +A+F++ L L KFL+D A+ Sbjct: 63 EGLAFNLTEIQEKEIHEGFHNLIHMLNHPEGGVQLNMMNAIFVTAALALLRKFLDDAKAL 122 Query: 163 YEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKP 222 Y+ + F T+F + IND+++++T GKI +LV ++ +M+L +++YFK WEKP Sbjct: 123 YQLEAFTTDFNKPTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEKP 182 Query: 223 FISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPN 282 F + T ++F+VD TTV+VPMM Q +Y D L C+V+R+ Y G AT F +LP Sbjct: 183 FEAEHTEEREFFVDAETTVKVPMMYQMGRFDFYF-DEELSCTVVRLHYNGSATAFLVLPA 241 Query: 283 QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLF 342 +GKM+++E+ L E + +W++ L F + + L+ PKFSISGSY + L ++G D+F Sbjct: 242 KGKMKQLEQTLDKETIQKWSDHL----FQRFMNLYFPKFSISGSYEISNTLRKMGIVDVF 297 Query: 343 SKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRP 402 + ADLSGIT L+ SK HKA+LDVDE GTEAAAAT+ I S + F+ P Sbjct: 298 TNQADLSGITGSPDLKVSKVVHKASLDVDEKGTEAAAATAVEIMPISFPPT---IEFSHP 354 Query: 403 FLVVIFSTSTQSVLFLGKVVDPT 425 FL++IF T S LF+GK+V+PT Sbjct: 355 FLMLIFDRDTNSTLFIGKIVNPT 377 >6HGE-B nrPDB Length = 409 Score = 333 bits (853), Expect = 1e-91, Method: Compositional matrix adjust. Identities = 178/380 (46%), Positives = 238/380 (62%), Gaps = 10/380 (2%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +A AN DFAF Y + + P KN+ FSPLSIS A A LSLGA + + ++IL+GL FNLT Sbjct: 35 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 94 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E SE+++H+ FQHLL TLN L+ +G+A+F+ L L +F D +Y ++ F T Sbjct: 95 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 154 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 +F D+ +LIND+VK TRGKI DL+ +L +MVLVNYI+FKA WE PF T Sbjct: 155 DFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQ 214 Query: 231 KDFYVDENTTVRVPMMLQDQEHHW---YLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 287 FY+ + V VPMM HH Y D L C+V++++Y G+A+ FILP+Q KM Sbjct: 215 SRFYLSKKKWVMVPMM---SLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPDQDKME 271 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 347 E+E +L+ E L RW + L R EL+LPKFSIS Y L+ IL +LG + F+ AD Sbjct: 272 EVEAMLSRETLNRWGDSLEFREIG---ELYLPKFSISRDYNLNDILLQLGIEEAFTSKAD 328 Query: 348 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT-NRHILRFNRPFLVV 406 LSGIT + L S+ HKA LDV E GTEA+AAT+ I SA R I+RFNRPFL++ Sbjct: 329 LSGITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMI 388 Query: 407 IFSTSTQSVLFLGKVVDPTK 426 I T S+ F+ KV +P + Sbjct: 389 IVDHFTWSIFFMSKVTNPKQ 408 >2VDY-A nrPDB Length = 373 Score = 331 bits (848), Expect = 5e-91, Method: Compositional matrix adjust. Identities = 173/376 (46%), Positives = 242/376 (64%), Gaps = 12/376 (3%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +A AN DFAF Y + + +P KNIF SP+SIS A AMLSLG C H+R+Q+L+GLGFNLT Sbjct: 7 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 66 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E SE+++H+GFQHL LE +G+ALFL +L+ L F D YE+++ Sbjct: 67 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 126 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 NF D + IN +VK +T+GKIVDL S L ++VLVNYI+FK W +PF + T Sbjct: 127 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 186 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290 ++FYVDE T V+VPMMLQ YLHD LPC +++M+Y G+ TVFFILP++GKM + Sbjct: 187 ENFYVDETTVVKVPMMLQSSTIS-YLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVI 245 Query: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350 L+ + + RW+ L +++L++PK +ISG Y L +L +G DLF+ A+ S Sbjct: 246 AALSRDTINRWSAGLTS----SQVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQANFSR 301 Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSA--QTNRHILRFNRPFLVVIF 408 IT+ +L++SK HKA L ++E GTEAA A F A ++ ILRFN+PF+++IF Sbjct: 302 ITQDAQLKSSKVVHKAVLQLNEEGTEAAGAM-----FLEAIPRSKPIILRFNQPFIIMIF 356 Query: 409 STSTQSVLFLGKVVDP 424 T S LFL +V++P Sbjct: 357 DHFTWSSLFLARVMNP 372 >3NE4-A nrPDB Length = 424 Score = 324 bits (831), Expect = 4e-89, Method: Compositional matrix adjust. Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%) Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPSL-KIAPANADFAF 60 + + +LLL GL L L + G++ +++SH + P+ KI P A+FAF Sbjct: 11 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 65 Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120 Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G Sbjct: 66 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 125 Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180 FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT + Sbjct: 126 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 185 Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240 IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT Sbjct: 186 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 245 Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300 V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ + Sbjct: 246 VKVPMMKRLGMFNIQ-HCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 304 Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360 + +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S Sbjct: 305 FLENEDRRS----ASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 360 Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420 K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK Sbjct: 361 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 417 Query: 421 VVDPTK 426 VV+PT+ Sbjct: 418 VVNPTQ 423 >3DY0-A nrPDB Length = 336 Score = 322 bits (826), Expect = 2e-88, Method: Compositional matrix adjust. Identities = 160/338 (47%), Positives = 227/338 (67%), Gaps = 6/338 (1%) Query: 51 IAPANA-DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 +AP++ DF F Y +AS P +NIFFSP+SIS + AMLSLGA S ++ QILEGLG NL Sbjct: 4 VAPSSRRDFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNL 63 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 + SE ++HRGFQ LL LN P G + +G+ALF + F++ +Y A F Sbjct: 64 QKSSEKELHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFP 123 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 TNF D+ G ++ IND+V K+T+GKIVDL+ L + ++++VNYI+FKA WE F T Sbjct: 124 TNFRDSAGAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQ 183 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289 +DFYV T VRVPMM ++ ++H YL DR L C V+ + Y+G+AT FILP++GKM+++ Sbjct: 184 EQDFYVTSETVVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQV 242 Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349 E L+ + L +W + +KR +LEL+LPKFSI GSY L+++LP LG +++F+ ADLS Sbjct: 243 ENGLSEKTLRKWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLS 298 Query: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 387 GI+ ++ S+ HKA ++VDE+GT AAAAT F Sbjct: 299 GISNHSNIQVSEMVHKAVVEVDESGTRAAAATGTIFTF 336 >1YXA-A nrPDB Length = 398 Score = 317 bits (812), Expect = 6e-87, Method: Compositional matrix adjust. Identities = 179/398 (44%), Positives = 242/398 (60%), Gaps = 3/398 (0%) Query: 27 DGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAY 86 DG +++ Q+ + G SL +A N DFAF Y + + P NI FSPLSISAA Sbjct: 3 DGTLGMDAAVQEDHDNGTQLDSLTLASINTDFAFSLYKELVLKNPDTNIVFSPLSISAAL 62 Query: 87 AMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLS 146 A++SLGA ++ +ILEGL FNLTE SE+D+H+GF HLL LN P ++ GSALF+ Sbjct: 63 ALVSLGAKGNTLEEILEGLKFNLTETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFIE 122 Query: 147 HNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVL 206 + L +F +Y+A+ F +F +LIND+V+K+T+G I +LVS+L K L Sbjct: 123 KRQQILTEFQEKAKTLYQAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVSDLDKRTL 182 Query: 207 MVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVL 266 MVLVNYIYFKA W+ PF T +FY + V VPMM + Y D L C+V+ Sbjct: 183 MVLVNYIYFKAKWKVPFDPLDTFKSEFYCGKRRPVIVPMMSMEDLTTPYFRDEELSCTVV 242 Query: 267 RMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGS 326 + Y G+A+ FILP+QG+M+++E L PE L +W N L+ R ELHLPKFSIS Sbjct: 243 ELKYTGNASALFILPDQGRMQQVEASLQPETLRKWKNSLKPRMID---ELHLPKFSISTD 299 Query: 327 YVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIK 386 Y L+ +L +LG ++FS ADLS IT + L S+ HKA LDV E GTEAAAAT Sbjct: 300 YSLEDVLSKLGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGVKFV 359 Query: 387 FFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 SA+ + FNRPFL++IF T T+ F+ K+ +P Sbjct: 360 PMSAKLYPLTVYFNRPFLIMIFDTETEIAPFIAKIANP 397 >2XN5-A nrPDB Length = 350 Score = 308 bits (788), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 155/332 (46%), Positives = 219/332 (65%), Gaps = 6/332 (1%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 K++ NADFAF Y ETP KNIFFSP+SISAA MLS GAC ++++I+E LGFNL Sbjct: 10 KMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNL 69 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 T+ ++ GFQHL+ +LN P LE ++G+ALF+ +LK LAKFLND +YE ++F Sbjct: 70 TDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFS 129 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 T+F + Q IN HV+ +T+GK+V L+ +LK + +MVLVNYI+FKA W PF S+T Sbjct: 130 TDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTE 189 Query: 230 -PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMRE 288 F +D+ TTV+VPMM Q E +++L D L C+VL+MDY +A F+LP +G+M Sbjct: 190 DSSSFLIDKTTTVQVPMMHQ-MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMES 248 Query: 289 IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL 348 +E ++ + L +WN LL+K ++L +PKFSIS +Y L L ++G +S+ AD Sbjct: 249 VEAAMSSKTLKKWNRLLQK----GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADF 304 Query: 349 SGITKQQKLEASKSFHKATLDVDEAGTEAAAA 380 SG+T+ L+ S + HKA L + E GTEAA A Sbjct: 305 SGLTEDNGLKLSNAAHKAVLHIGEKGTEAAGA 336 >1QMB-A nrPDB Length = 326 Score = 293 bits (749), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 157/331 (47%), Positives = 214/331 (64%), Gaps = 7/331 (2%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 KI P A+FAF Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNL Sbjct: 1 KITPNLAEFAFSLYRQLAHQS-STNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNL 59 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 TE+ E+ +H GFQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F Sbjct: 60 TEIPEAAIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 119 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 NF DT + IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T Sbjct: 120 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 179 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289 +DF+VD+ TTV+VPMM + + H + L VL M Y G+AT F LP++GK++ + Sbjct: 180 EEDFHVDQVTTVKVPMMKRLGMFNIQ-HCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHL 238 Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349 E LT +++ ++ N + LHLPK SI+G+Y L +L +LG T +FS ADLS Sbjct: 239 ENELTHDIITKF-----LENDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 293 Query: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAA 380 G+T++ L+ SK+ HKA L +DE GTEAA A Sbjct: 294 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGA 324 >2V95-A nrPDB Length = 371 Score = 271 bits (692), Expect = 5e-73, Method: Compositional matrix adjust. Identities = 146/374 (39%), Positives = 215/374 (57%), Gaps = 12/374 (3%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +AP N DFAF Y + + P KN SP+SIS A AM+SLG+ ++Q L+ LGFNLT Sbjct: 9 LAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAMVSLGSA---QTQSLQSLGFNLT 65 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E SE+++H+ FQ+L + L GLE +G+A+FL LK FL D YE++ Sbjct: 66 ETSEAEIHQSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYESEALAI 125 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 +F D Q IN HVK +T+GKI + S+L +LVNYI+ + +WE PF T Sbjct: 126 DFEDWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLRGIWELPFSPENTRE 185 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290 +DFYV+E +TV+VPMM+Q Y D PC +++MDY G+ T FFILP+QG+M + Sbjct: 186 EDFYVNETSTVKVPMMVQSGSIG-YFRDSVFPCQLIQMDYVGNGTAFFILPDQGQMDTVI 244 Query: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350 L+ + + RW L+ R ++ L++PKFS+S +Y L +L L DL + +D SG Sbjct: 245 AALSRDTIDRWGKLMTPR----QVNLYIPKFSMSDTYDLKDVLEDLNIKDLLTNQSDFSG 300 Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFST 410 TK L + HKA L +DE + + S + ++FN+PF++++F Sbjct: 301 NTKDVPLTLTM-VHKAMLQLDEGNVLPNSTNGAPLHLRSEPLD---IKFNKPFILLLFDK 356 Query: 411 STQSVLFLGKVVDP 424 T S L + +VV+P Sbjct: 357 FTWSSLMMSQVVNP 370 >4Y40-A nrPDB Length = 414 Score = 244 bits (624), Expect = 4e-65, Method: Compositional matrix adjust. Identities = 130/379 (34%), Positives = 219/379 (57%), Gaps = 18/379 (4%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 ++A N D F+ +A PG+NIF SPLSIS A++ML LGA + +I +G FN Sbjct: 47 ELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQG--FNF 104 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 ++ E D+H GF +++H L L+ +G+ LF+ L+ KFL D Y A+ Sbjct: 105 RKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFYSAETIL 164 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 TNF + + IND + ++T GKI +L+ + +M+L NYI+F+A W+ F + T Sbjct: 165 TNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEFDPNVTK 224 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289 +DF++++N++V+VPMM + + D+ L C++L + Y+ + T FILP++GK++ + Sbjct: 225 EEDFFLEKNSSVKVPMMFRSGIYQVGYDDK-LSCTILEIPYQKNITAIFILPDEGKLKHL 283 Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349 E+ L + RW LL +R + + +P+ ++G++ L + L +G + +F + DL+ Sbjct: 284 EKGLQVDTFSRWKTLLSRR----VVCVSVPRLHMTGTFDLKKTLSYIGVSKIFEEHGDLT 339 Query: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT----NRHILRFNRPFLV 405 I + L+ ++ HKA L +DE GTE AA T AQT ++ ++P+L+ Sbjct: 340 KIAPHRSLKVGEAVHKAELKMDERGTEGAAGT-------GAQTLPMETPLCVKIDKPYLL 392 Query: 406 VIFSTSTQSVLFLGKVVDP 424 +I+S SVLFLGK+V+P Sbjct: 393 LIYSEKIPSVLFLGKIVNP 411 >1ATT-A nrPDB Length = 429 Score = 184 bits (468), Expect = 5e-47, Method: Compositional matrix adjust. Identities = 131/388 (33%), Positives = 212/388 (54%), Gaps = 21/388 (5%) Query: 50 KIAPANADFAFRFY-YLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ AN+ FA FY +L S+ NIF SPLSIS A+AM LGAC+++ +Q++E F+ Sbjct: 47 ELSKANSHFATAFYQHLADSKNNNDNIFLSPLSISTAFAMTKLGACNNTLTQLMEVFKFD 106 Query: 109 -LTELSESDVHRGFQHLLHTL-NLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAK 166 ++E + +H F L L E + LF ++ F + + + VY AK Sbjct: 107 TISEKTSDQIHFFFAKLNCRLYRKANKSSELVSANRLFGDKSITFNETYQDISEVVYGAK 166 Query: 167 LFHTNFYDTVGTIQL-INDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKALWEKPF 223 L +F +L IN + +T G+I D++ + + ++VLVN IYFK LW+ F Sbjct: 167 LQPLDFKGNAEQSRLTINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLWKSKF 226 Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCS--VLRMDYKGD-ATVFFIL 280 T + FY + + V MM Q+ + + R + S VL + +KGD T+ IL Sbjct: 227 SPENTRKELFYKADGESCSVLMMYQESKFRY----RRVAESTQVLELPFKGDDITMVLIL 282 Query: 281 PNQGK-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFT 339 P K + ++E+ LTP+ML W + L + L +H+P+F I S+ + + L +G Sbjct: 283 PKLEKTLAKVEQELTPDMLQEWLDELTE----TLLVVHMPRFRIEDSFSVKEQLQDMGLE 338 Query: 340 DLFS-KWADLSGITKQQK--LEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHI 396 DLFS + + L GI + + L S +FHKA L+V+E G+EAAA+T +I S ++R Sbjct: 339 DLFSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLNSDRVT 398 Query: 397 LRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 + NRPFLV+I + +++F+G+V +P Sbjct: 399 FKANRPFLVLIREVALNTIIFMGRVANP 426 >4EB1-I nrPDB Length = 440 Score = 180 bits (457), Expect = 9e-46, Method: Compositional matrix adjust. Identities = 133/396 (33%), Positives = 205/396 (51%), Gaps = 29/396 (7%) Query: 50 KIAPANADFAFRFY-YLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ AN+ FA FY +L S+ NIF SPLSIS A+AM LGAC+ + Q++E F+ Sbjct: 50 ELSKANSRFATTFYQHLADSKNDNDNIFLSPLSISTAFAMTKLGACNDTLQQLMEVFKFD 109 Query: 109 -LTELSESDVHRGFQHLLHTLNLPGHGLETRV-GSALFLSHNLKFLAKFLNDTMAVYEAK 166 ++E + +H F L L + V + LF +L F + + + VY AK Sbjct: 110 TISEKTSDQIHFFFAKLNCRLYRKANKASKLVSANRLFGDKSLTFNETYQDISELVYGAK 169 Query: 167 LFHTNFYDTVGTIQL-INDHVKKETRGKIVDLVSELKKDVL----------MVLVNYIYF 215 L +F + + IN V +T G+I D++ +VL +VLVN IYF Sbjct: 170 LQPLDFKENAEQSRAAINKWVSNKTEGRITDVIPSEAINVLVLVNTRTSTVLVLVNTIYF 229 Query: 216 KALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLP--CSVLRMDYKGD 273 K LW+ F T + FY + + MM Q+ + + R + VL + +KGD Sbjct: 230 KGLWKSKFSPENTRKELFYKADGESCSASMMYQEGKFRY----RRVAEGTQVLELPFKGD 285 Query: 274 -ATVFFILPNQGK-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQ 331 T+ ILP K + ++E+ LTPE+L W + L + L +H+P+F I + L + Sbjct: 286 DITMVLILPKPEKSLAKVEKELTPEVLQEWLDELEEM----MLVVHMPRFRIEDGFSLKE 341 Query: 332 ILPRLGFTDLFS-KWADLSGITKQQK--LEASKSFHKATLDVDEAGTEAAAATSFAIKFF 388 L +G DLFS + + L GI + + L S +FHKA L+V+E G+EAAA+T+ I Sbjct: 342 QLQDMGLVDLFSPEKSKLPGIVAEGRDDLYVSDAFHKAFLEVNEEGSEAAASTAVVIAGR 401 Query: 389 SAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 S NR + NRPFLV I +++F+G+V +P Sbjct: 402 SLNPNRVTFKANRPFLVFIREVPLNTIIFMGRVANP 437 >5INW-A nrPDB Length = 421 Score = 175 bits (444), Expect = 3e-44, Method: Compositional matrix adjust. Identities = 113/340 (33%), Positives = 180/340 (52%), Gaps = 7/340 (2%) Query: 50 KIAPANADFAFRFY-YLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +IA A FR Y ++ P NIFFSPLSI++A +++ GA +R+++ LGF Sbjct: 80 RIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASALGVVTAGANGSTRAELDTALGFK 139 Query: 109 --LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAK 166 L ++ + F L L G E + +F L +F ++++ Sbjct: 140 EFLHGKKKAKSMKYFARLNGALYKRSAGFELMGKNVVFSKKGLWLYRQFTRTVAHLFKSN 199 Query: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226 + +F D+ ++L+N +++K T K D++S++ D +V+VN IYFK W F Sbjct: 200 VRSVDFGDSKNAVELMNAYIEKVTSKKFPDVISDVDTDTSLVIVNVIYFKGSWGNKFEPD 259 Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGK- 285 T F+V+ + ++ VP M Q + Y DR L +V+++ Y+G A++ I+P++ + Sbjct: 260 LTKNVRFWVNSSYSMMVPTMHQRAKLS-YTQDRKLRSTVVKLPYEGGASMLVIVPHRTED 318 Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 + ++EE ++ E L W +LL N Y ++L LPKF IS SY L L +G + +FS Sbjct: 319 LPKVEESVSQEQLEEWLSLLGPSNHY--VQLSLPKFKISVSYDLKAYLSAMGMSSMFSYG 376 Query: 346 ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAI 385 ADLS IT QKL K HK+ L V+E GTEA A T I Sbjct: 377 ADLSRITGMQKLHVDKITHKSVLHVNEEGTEAKAETVVGI 416 >4AJT-A nrPDB Length = 427 Score = 165 bits (417), Expect = 4e-41, Method: Compositional matrix adjust. Identities = 113/383 (29%), Positives = 196/383 (51%), Gaps = 17/383 (4%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 107 S +++ + F F I+ G N+ FSP +S A L LG ++ QI GL Sbjct: 55 SQQLSNETSSFGFNLLRKISMRHDG-NVIFSPFGLSVAMVNLMLGTKGETKVQIENGL-- 111 Query: 108 NLTELSESD---VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 NL LS++ + F+ + T + L GS F+ + + N + ++ Sbjct: 112 NLQALSQAGPLILPALFKKVKETFS-SNRDLGLSQGSFAFIHKDFDIKETYFNLSKKYFD 170 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 224 + NF ++ LIN + KET GKI L E+ + ++LV+Y+ FK W PF Sbjct: 171 IEYVSINFQNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPFD 230 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ- 283 S T F++D+ ++VPMM ++ + D+ C +L++ Y+G+AT+ +L + Sbjct: 231 PSFTEADTFHLDKYRAIKVPMMYREG-NFTSTFDKKFRCHILKLPYQGNATMLVVLMEKT 289 Query: 284 GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 G +E+ LT +++ W ++ R K+E+ PKF ++ Y + ++L ++G LFS Sbjct: 290 GDYLALEDYLTVDLVETWLQNMKTR----KMEVFFPKFKLNQRYEMHELLKQMGIRRLFS 345 Query: 344 KWADLSGITKQQK-LEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRP 402 ADLS ++ + L+ S+ ++ L+VDE GTEA + T I +S ++ NRP Sbjct: 346 TSADLSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPP---AIKVNRP 402 Query: 403 FLVVIFSTSTQSVLFLGKVVDPT 425 F +I+ ++ +LFLG+VV+PT Sbjct: 403 FHFIIYEEMSRMLLFLGRVVNPT 425 >3LW2-A nrPDB Length = 379 Score = 164 bits (414), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 108/381 (28%), Positives = 194/381 (50%), Gaps = 28/381 (7%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 DF + + + + +N+ FSP +S+ AML + +R QI + +GF + E Sbjct: 14 DFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGFKVNE----- 68 Query: 117 VHRGFQHLLHTLNL----PGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNF 172 +G H L L+ P + E A+F+ +L+ + F+ +++ + +F Sbjct: 69 --KGTAHALRQLSKELMGPWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVDF 126 Query: 173 YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFKALWEKPFISSRTTP 230 + +IND V++ T+G I DL+++ D L +VLVN +YF W+ PF+ + T Sbjct: 127 SEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTHQ 186 Query: 231 KDFYVDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGDATVFFILPNQGK--- 285 + F+ + +TV VPMM Q + ++ + L V+ + Y+GD FI K Sbjct: 187 RLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQGDTLSMFIAAPFEKDVH 246 Query: 286 MREIEEVLTPEMLMRW-NNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 + + +L E++ +W N+ R L LPKFS+ L L +LG D+FS Sbjct: 247 LSALTNILDAELIRQWKGNMTRLPRL-----LILPKFSLETEVDLRGPLEKLGMPDMFSA 301 Query: 345 -WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPF 403 AD + ++ Q++L +++ K ++V+E+GT A+++T+F I A T I +R F Sbjct: 302 TLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVI---DRSF 358 Query: 404 LVVIFSTSTQSVLFLGKVVDP 424 L V+ T+++LF+G+V++P Sbjct: 359 LFVVRHNPTETILFMGQVMEP 379 >1C5G-A nrPDB Length = 402 Score = 163 bits (413), Expect = 1e-40, Method: Compositional matrix adjust. Identities = 114/403 (28%), Positives = 198/403 (49%), Gaps = 40/403 (9%) Query: 43 GEGS----PSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSR 98 GEGS P +A +DF R + +A + +N+ FSP +++ AML L ++ Sbjct: 19 GEGSAVHHPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQ 78 Query: 99 SQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLND 158 QI +GF ++ + + +HL L P + E A+F+ +LK + F+ Sbjct: 79 QQIQAAMGF---KIDDKGMAPALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPH 135 Query: 159 TMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFK 216 ++ + + +F + +IND VK T+G I +L+ + D L +VLVN +YF Sbjct: 136 FFRLFRSTVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFN 195 Query: 217 ALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQ----------EHHWYLHDRYLPCSVL 266 W+ PF S T + F+ + +TV VPMM Q + H+Y +L Sbjct: 196 GQWKTPFPDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYY--------DIL 247 Query: 267 RMDYKGDATVFFILPNQGK---MREIEEVLTPEMLMRW-NNLLRKRNFYKKLELHLPKFS 322 + Y GD FI K + + +L+ +++ W N+ R L LPKFS Sbjct: 248 ELPYHGDTLSMFIAAPYEKEVPLSALTNILSAQLISHWKGNMTRLPRL-----LVLPKFS 302 Query: 323 ISGSYVLDQILPRLGFTDLFSKW-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAAT 381 + L + L LG TD+F ++ AD + ++ Q+ L +++ K ++V+E+GT A+++T Sbjct: 303 LETEVDLRKPLENLGMTDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSST 362 Query: 382 SFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 + + SA+ + +RPFL V+ T +VLF+G+V++P Sbjct: 363 AVIV---SARMAPEEIIMDRPFLFVVRHNPTGTVLFMGQVMEP 402 >4GA7-A nrPDB Length = 389 Score = 161 bits (407), Expect = 6e-40, Method: Compositional matrix adjust. Identities = 130/387 (33%), Positives = 201/387 (51%), Gaps = 22/387 (5%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 +++ AN FA + ++ P NIF SP SIS+A AM+ LG ++ +Q+ + FN Sbjct: 13 QLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFNT 72 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 E +VH FQ L +N G ++ + L+ FL +FL T Y A L Sbjct: 73 VE----EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLAS 128 Query: 170 TNF-YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFKALWEKPFISS 226 +F + + + IN VK +T GKI +L++ D + +VLVN IYFK W+ F+ Sbjct: 129 VDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMKE 188 Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHW-YLHDRYLPCSVLRMDYKGDA-TVFFILPNQ- 283 TT F +++ V MM Q ++ + Y+ D L C VL + Y+G+ ++ +LP+ Sbjct: 189 ATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIED--LKCRVLELPYQGEELSMVILLPDDI 246 Query: 284 ----GKMREIEEVLTPEMLMRWNNLLRKRNF-YKKLELHLPKFSISGSYVLDQILPRLGF 338 +++IEE LT E L W + N + ++ + LP+F + SY L+ L RLG Sbjct: 247 EDESTGLKKIEEQLTLEKLHEWT---KPENLDFIEVNVSLPRFKLEESYTLNSDLARLGV 303 Query: 339 TDLF-SKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHIL 397 DLF S ADLSG++ + + SK HK+ ++V+E GTEAAAAT+ F + Sbjct: 304 QDLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMDDPEENFT 363 Query: 398 RFNRPFLVVIFSTSTQSVLFLGKVVDP 424 + PFL I S+ S+LFLG+ P Sbjct: 364 A-DHPFLFFIRHNSSGSILFLGRFSSP 389 >4ZK0-A nrPDB Length = 390 Score = 160 bits (405), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 130/392 (33%), Positives = 199/392 (50%), Gaps = 23/392 (5%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN-L 109 ++ AN F F + ++ NIF+SP+SI++A M+ LGA ++ QI + L F+ + Sbjct: 4 LSEANTKFMFDLFQQF-RKSKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFDQV 62 Query: 110 TELS-----------ESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLND 158 TE + +VH FQ LL N E ++ + LF FL ++L+ Sbjct: 63 TENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYLDA 122 Query: 159 TMAVYEAKLFHTNFYDT-VGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYF 215 Y+ + +F + + + IN V+ +T KI +L+ E + + +VLVN IYF Sbjct: 123 IKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAIYF 182 Query: 216 KALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWY-LHDRYLPCSVLRMDYKG-D 273 K WEK F T + F+ ++NT + MM Q H+ L D + VL + YKG D Sbjct: 183 KGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFHFASLED--VQAKVLEIPYKGKD 240 Query: 274 ATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQI 332 ++ +LPN+ ++++EE LT E LM W +L R +++LHLP+F + SY L Sbjct: 241 LSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMRE--TRVDLHLPRFKVEESYDLKDT 298 Query: 333 LPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT 392 L +G D+F+ ADLSG+T + L S HKA ++V E G EAAAAT+ S + Sbjct: 299 LRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPTS 358 Query: 393 NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 N PFL I T S+LF G+ P Sbjct: 359 TNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390 >3NDA-A nrPDB Length = 377 Score = 160 bits (404), Expect = 1e-39, Method: Compositional matrix adjust. Identities = 117/376 (31%), Positives = 181/376 (48%), Gaps = 11/376 (2%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 K+ AN F R + S P KN+FFSP S+S A M GA ++ ++ +GLGF+ Sbjct: 6 KLTKANNRFGLRLLRALPS-GPEKNVFFSPYSVSTAMGMAFAGARGQTQQELSQGLGFSD 64 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 +L+++ V + H L V +A + L L + + + + A+L Sbjct: 65 VDLTDAGVLDAYTHHTERLKSTPSNSTLDVANAAAIQRTLALLNSYESALQSSFGAELHK 124 Query: 170 TNFY-DTVGTIQLINDHVKKETRGKIVDLVSE-LKKDVLMVLVNYIYFKALWEKPFISSR 227 +F + + +N+ VK++T KI L +E L D L+VL+N IYFK W F+ Sbjct: 125 VDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTAFVKEH 184 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILPNQGKM 286 T + F+ T V V M + + D L V+ + Y+G D T+ +LP + Sbjct: 185 TEKRQFFNGGVTPVEVDTMRLEARIKYRFFDD-LQVEVVELPYRGLDYTMAILLPKENTG 243 Query: 287 RE-IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 E +++ LT + + + LR+R K+ + LPKF + Y L L LG +F Sbjct: 244 VEGLKQNLTIDRFQNYLSDLRER----KITVLLPKFKLETKYSLKAPLQSLGIKQIFESG 299 Query: 346 ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLV 405 ADLSGI L S HKA ++V+E GT AAA T I +S + R + PFL Sbjct: 300 ADLSGIN-DGSLRVSAVEHKAVVEVNEEGTVAAATTGVVIVPYSLGPEPVVFRVDHPFLF 358 Query: 406 VIFSTSTQSVLFLGKV 421 I +T T + F+G+V Sbjct: 359 FIRNTRTDDIFFVGQV 374 >1JMJ-A nrPDB Length = 480 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 118/405 (29%), Positives = 197/405 (48%), Gaps = 22/405 (5%) Query: 32 SNSSHQQILETGEGSPSL-KIAPANADFAFRFYYLIASETPG-KNIFFSPLSISAAYAML 89 S+ S IL+ G + ++ NA FAF Y ++ + NIF +P+ IS A M+ Sbjct: 87 SDVSAGNILQLFHGKSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMI 146 Query: 90 SLGACSHSRSQILEGLGF----NLTELSE-SDVHRGFQHLLHTLNLPGHGLETRVGSALF 144 SLG + Q+ L F N + E + +H F+ L H L G R + L+ Sbjct: 147 SLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLY 206 Query: 145 LSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKD 204 + L F Y A+ +F D I N+H+ K T+G I D + + Sbjct: 207 IQKQFPILLDFKTKVREYYFAEAQIADFSDP-AFISKTNNHIMKLTKGLIKDALENIDPA 265 Query: 205 VLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCS 264 M+++N IYFK W F T +F ++E V+V MM Q + + +D+ L C Sbjct: 266 TQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMM-QTKGNFLAANDQELDCD 324 Query: 265 VLRMDYKGDATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSI 323 +L+++Y G ++ ++P++ M+ +E LTP ++ RW + R E+ LPKF + Sbjct: 325 ILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRT----REVLLPKFKL 380 Query: 324 SGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSF 383 +Y L + L +G LF K +++GI+ Q++ H+ T+ V+E GT+A T+ Sbjct: 381 EKNYNLVESLKLMGIRMLFDKNGNMAGIS-DQRIAIDLFKHQGTITVNEEGTQATTVTTV 439 Query: 384 AIKFFSAQTNRHILRF--NRPFLVVIFSTSTQSVLFLGKVVDPTK 426 S Q +RF +RPFL +I+ T +LF+G+V +P++ Sbjct: 440 GFMPLSTQ-----VRFTVDRPFLFLIYEHRTSCLLFMGRVANPSR 479 >1HLE-A nrPDB Length = 345 Score = 159 bits (401), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 112/334 (33%), Positives = 179/334 (53%), Gaps = 21/334 (6%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 +++ AN FA + + P NIF SPLSIS+A AM+ LG ++ +Q+ + L F+ Sbjct: 4 QLSTANTHFAVDLFRALNESDPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFDT 63 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 E D+H FQ L +N PG ++ + L+ FLA FL T +Y A+L Sbjct: 64 VE----DIHSRFQSLNADINKPGAPYILKLANRLYGEKTYNFLADFLASTQKMYGAELAS 119 Query: 170 TNFYDTVGTIQL-INDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFKALWEKPFISS 226 +F + IN+ VK +T GKI +L+ + D + +VLVN IYFK W++ F+ Sbjct: 120 VDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQQKFMKE 179 Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHW-YLHDRYLPCSVLRMDYKG-DATVFFILPNQG 284 T F +++ T V MM Q ++ + Y+ D L C VL + Y+G + ++ +LP+ Sbjct: 180 ATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIED--LKCRVLELPYQGKELSMIILLPDDI 237 Query: 285 K-----MREIEEVLTPEMLMRWNNLLRKRNFY-KKLELHLPKFSISGSYVLDQILPRLGF 338 + + +IE+ LT + L W + N Y ++ +HLP+F + SY L L RLG Sbjct: 238 EDESTGLEKIEKQLTLDKLREWT---KPENLYLAEVNVHLPRFKLEESYDLTSHLARLGV 294 Query: 339 TDLFSKW-ADLSGITKQQKLEASKSFHKATLDVD 371 DLF++ ADLSG++ + L SK HK+ +D++ Sbjct: 295 QDLFNRGKADLSGMSGARDLFVSKIIHKSFVDLN 328 >1BY7-A nrPDB Length = 382 Score = 157 bits (396), Expect = 1e-38, Method: Compositional matrix adjust. Identities = 109/381 (28%), Positives = 188/381 (49%), Gaps = 15/381 (3%) Query: 54 ANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELS 113 AN FA + +A +P +N+F SP SIS+ AM+ +G+ + Q+ + L FN + Sbjct: 7 ANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFNEVGAA 66 Query: 114 ESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY 173 +H F+ L +N + LF + F +++ Y ++ +F Sbjct: 67 ADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQAVDFL 126 Query: 174 DTVGTI-QLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 + + IN VK +T+GKI +L+ E + D MVLVN +YFK W+ PF Sbjct: 127 ECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEKKLNGL 186 Query: 231 KDFYVDENTTVRVPMM-LQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-----G 284 F V+ V MM L+++ + Y+ D L +L + Y GD ++F +LP++ Sbjct: 187 YPFRVNSAQRTPVQMMYLREKLNIGYIED--LKAQILELPYAGDVSMFLLLPDEIADVST 244 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 + +E +T + L +W + + + ++E+++P+F + Y L IL +G D F+K Sbjct: 245 GLELLESEITYDKLNKWTS--KDKMAEDEVEVYIPQFKLEEHYELRSILRSMGMEDAFNK 302 Query: 345 W-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPF 403 A+ SG++++ L S+ FH+A +DV+E GTEAAA T + + + + PF Sbjct: 303 GRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQFVA-DHPF 361 Query: 404 LVVIFSTSTQSVLFLGKVVDP 424 L +I T +LF G+ P Sbjct: 362 LFLIMHKITNCILFFGRFSSP 382 >1UHG-A nrPDB Length = 385 Score = 147 bits (370), Expect = 1e-35, Method: Compositional matrix adjust. Identities = 112/399 (28%), Positives = 185/399 (46%), Gaps = 41/399 (10%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQI--------L 102 I A+ +F F + + +NIF+ P++I +A AM+ LGA +R+QI L Sbjct: 3 IGAASMEFCFDVFKELKVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRFDKL 62 Query: 103 EGLGFNLTELSES--DVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTM 160 G G ++ + +VH + +L+ + P + S L+ L ++L Sbjct: 63 PGFGDSIEAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEERYPILPEYLQCVK 122 Query: 161 AVYEAKLFHTNFYDTVGTI-QLINDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKA 217 +Y L NF +LIN V+ +T G I +++ S + MVLVN I FK Sbjct: 123 ELYRGGLEPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIVFKG 182 Query: 218 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQ---------DQEHHWYLHDRYLPCSVLRM 268 LWEK F T F V E + V MM Q E L LP + Sbjct: 183 LWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASEKMKILE---LPFA---- 235 Query: 269 DYKGDATVFFILPNQ-GKMREIEEVLTPEMLMRW--NNLLRKRNFYKKLELHLPKFSISG 325 G ++ +LP++ + ++E ++ E L W +N++ +R K++++LP+ + Sbjct: 236 --SGTMSMLVLLPDEVSGLEQLESIINFEKLTEWTSSNVMEER----KIKVYLPRMKMEE 289 Query: 326 SYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAI 385 Y L +L +G TD+FS A+LSGI+ + L+ S++ H A +++EAG E + + Sbjct: 290 KYNLTSVLMAMGITDVFSSSANLSGISSAESLKISQAVHAAHAEINEAGREVVGSAEAGV 349 Query: 386 KFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 A + R + PFL I +T +VLF G+ V P Sbjct: 350 ---DAASVSEEFRADHPFLFCIKHIATNAVLFFGRCVSP 385 >2H4Q-A nrPDB Length = 382 Score = 144 bits (364), Expect = 5e-35, Method: Compositional matrix adjust. Identities = 106/352 (30%), Positives = 174/352 (49%), Gaps = 30/352 (8%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 +++ + +F + + KNIFFSP SIS+A A+ L A + ++ E L F Sbjct: 44 QVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFEQ 103 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 E ++H GF+ LL N P + R + +++ L +L + Y+A+ Sbjct: 104 AE----NIHSGFKELLTAFNKPRNNYSLRSANRIYVEKTYALLPTYLQLSKKYYKAEPQK 159 Query: 170 TNFYDT-VGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISS 226 NF + + IN V+K+T KI +L+S ++K ++LVN IYFKA WE F + Sbjct: 160 VNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQAE 219 Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYK--------GDATVFF 278 +T+ + F + +N + V MM Y+ D + + +M++K + ++F Sbjct: 220 KTSIQPFRLSKNKSKPVKMM--------YMRDTFPVLIMEKMNFKMIELPYVKRELSMFI 271 Query: 279 ILPNQGK-----MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQIL 333 +LP+ K + ++E LT E L W + K ++LHLPKFS+ L L Sbjct: 272 LLPDDIKDGTTGLEQLERELTYERLSEWAD--SKMMTETLVDLHLPKFSLEDRIDLRDTL 329 Query: 334 PRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAI 385 +G T F+ AD G+T ++ L SK H++ + VDE GTEA AAT+ I Sbjct: 330 RNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGTEAVAATAVII 381 >4AJU-A nrPDB Length = 387 Score = 144 bits (362), Expect = 9e-35, Method: Compositional matrix adjust. Identities = 99/336 (29%), Positives = 170/336 (50%), Gaps = 14/336 (4%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 ++A ++F F I+ G N+ FSP +S A L LGA + +QI GL Sbjct: 53 QLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGLHLQA 111 Query: 110 TELSESDVHRG-FQHLLHTLNLPGHGLETRV--GSALFLSHNLKFLAKFLNDTMAVYEAK 166 + ++ + F+ L TL+ LE + GS F+ + F N + ++ + Sbjct: 112 LKPTKPGLLPSLFKGLRETLS---RNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDTE 168 Query: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226 NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF Sbjct: 169 CVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDPV 228 Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GK 285 T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L + G Sbjct: 229 FTEVDTFHLDKYKTIKVPMMYGAGKFASTF-DKNFRCHVLKLPYQGNATMLVVLMEKMGD 287 Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 +E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS + Sbjct: 288 HLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSPF 343 Query: 346 ADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAA 380 ADLS ++ + L+ S+ + ++VDE GTEA A Sbjct: 344 ADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAG 379 >1IMV-A nrPDB Length = 398 Score = 141 bits (356), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 107/386 (27%), Positives = 186/386 (48%), Gaps = 22/386 (5%) Query: 47 PSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLG 106 P K+A A ++F + Y + +S +P N+ SPLS++ A + LSLGA + S I L Sbjct: 30 PVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLSPLSVATALSALSLGADERTESIIHRALY 89 Query: 107 FNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAK 166 ++L +S D+H ++ LL T+ P L++ S + L+ + F+ Y + Sbjct: 90 YDL--ISSPDIHGTYKELLDTVTAPQKNLKS--ASRIVFEKKLRIKSSFVAPLEKSYGTR 145 Query: 167 ---LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPF 223 L D +Q IN+ V+ + +GK+ E+ ++ ++L+ +FK W F Sbjct: 146 PRVLTGNPRLD----LQEINNWVQAQMKGKLARSTKEIPDEISILLLGVAHFKGQWVTKF 201 Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ 283 S +T+ +DFY+DE TVRVPMM + Y D L C + ++ G ++ F LP + Sbjct: 202 DSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLDSDLSCKIAQLPLTGSMSIIFFLPLK 261 Query: 284 --GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDL 341 + IEE LT E + + L+ L +PK +S + + L + L Sbjct: 262 VTQNLTLIEESLTSEFIHDIDRELKTVQAV----LTVPKLKLSYEGEVTKSLQEMKLQSL 317 Query: 342 FSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNR 401 F D S IT + ++ ++ H+A + +E G + + + H+ N+ Sbjct: 318 FDS-PDFSKITG-KPIKLTQVEHRAGFEWNEDGAGTTPSPGLQPAHLTFPLDYHL---NQ 372 Query: 402 PFLVVIFSTSTQSVLFLGKVVDPTKP 427 PF+ V+ T T ++LF+GK++DP P Sbjct: 373 PFIFVLRDTDTGALLFIGKILDPRGP 398 >4KDS-A nrPDB Length = 386 Score = 139 bits (350), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 106/378 (28%), Positives = 178/378 (47%), Gaps = 21/378 (5%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 DF R + +A + G N+ FSP ++ AM LGA ++ + LGF+L E + Sbjct: 21 DFGMRVFSQVAQNSKGSNLAFSPYGVATILAMAQLGAGGNTLKTLNAKLGFSLQERGMAR 80 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTV 176 R Q + + G+E + S + + + F ++A +F Sbjct: 81 QQRLLQRDISS----EEGVE--LASGVMVERKMALEKGFRRGLGKAFQASPHQLDFSRPD 134 Query: 177 GTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFY 234 + +IN V T G I +S L + MVL+N ++F+ LW+ PF T + F+ Sbjct: 135 QALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALHFQGLWKVPFDPKMTEERLFH 194 Query: 235 VDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGDA-TVFFILP--NQGKMREI 289 ++V VPMM + ++ + V+ + Y+G++ ++ + P + + + Sbjct: 195 CANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPYEGESLSMLLVSPFEPETPVSSL 254 Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS-KWADL 348 LT + L +W +R K +L LP+F++ L IL ++G D+F+ AD Sbjct: 255 SSELTTQRLQQWRQEMRS----VKRQLVLPRFTLDSEVELKSILIQMGLGDMFNLAKADF 310 Query: 349 SGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIF 408 + IT +Q L SK K ++V+E GT+A+AAT A FS I NRPFL +I Sbjct: 311 TRITTEQPLCVSKVLQKVKIEVNEEGTKASAAT--AAILFSRMAVEEIT-MNRPFLFLIH 367 Query: 409 STSTQSVLFLGKVVDPTK 426 ST +VLF+G+V P + Sbjct: 368 HKSTGAVLFMGQVNQPQQ 385 >2H4P-A nrPDB Length = 394 Score = 139 bits (349), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 108/376 (28%), Positives = 177/376 (47%), Gaps = 50/376 (13%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 +++ + +F + + KNIFFSP SIS+A A+ L A + ++ E L F Sbjct: 28 QVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFTE 87 Query: 110 TELSES------------------------DVHRGFQHLLHTLNLPGHGLETRVGSALFL 145 +ES ++H GF+ LL N P + R + +++ Sbjct: 88 AVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNYSLRSANRIYV 147 Query: 146 SHNLKFLAKFLNDTMAVYEAKLFHTNFYDTV-GTIQLINDHVKKETRGKIVDLVS--ELK 202 L +L + Y+A+ NF + + IN V+K+T KI +L+S ++K Sbjct: 148 EKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVK 207 Query: 203 KDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLP 262 ++LVN IYFKA WE F + +T+ + F + +N + V MM Y+ D + Sbjct: 208 ATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMM--------YMRDTFPV 259 Query: 263 CSVLRMDYK--------GDATVFFILPNQGK-----MREIEEVLTPEMLMRWNNLLRKRN 309 + +M++K + ++F +LP+ K + ++E LT E L W + K Sbjct: 260 LIMEKMNFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWAD--SKMM 317 Query: 310 FYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLD 369 ++LHLPKFS+ L L +G T F+ AD G+T ++ L SK H++ + Sbjct: 318 TETLVDLHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVA 377 Query: 370 VDEAGTEAAAATSFAI 385 VDE GTEAAAAT+ I Sbjct: 378 VDEKGTEAAAATAVII 393 >3F02-A nrPDB Length = 359 Score = 137 bits (344), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 91/337 (27%), Positives = 167/337 (49%), Gaps = 15/337 (4%) Query: 54 ANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELS 113 A AD + Y + + +NI FSPLSI+ A M+ LGA ++ +I +G++ L Sbjct: 22 AIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYD--SLK 79 Query: 114 ESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY 173 + + + + ++ ++LF+ + +FL + A + H +F Sbjct: 80 NGEEFSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDFS 139 Query: 174 DTVGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRTTPK 231 V IN V+ T + DLVS + + L+N +YFK W+ F T Sbjct: 140 QNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRTF 199 Query: 232 DFYVDENTTVRVPMMLQDQEHHW-YLHDRYLPCS----VLRMDYKGDA-TVFFILPNQG- 284 F D+ + V++PMM Q E ++ D VL + Y+GD ++ +L Q Sbjct: 200 SFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQEV 259 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 + +E ++ +++ W N ++K+ K+E++LP+F++ L +L LG T++F K Sbjct: 260 PLATLEPLVKAQLVEEWANSVKKQ----KVEVYLPRFTVEQEIDLKDVLKALGITEIFIK 315 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAAT 381 A+L+G++ +++ SK+ HK+ L+V+E G+EAAA + Sbjct: 316 DANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVS 352 >4P0F-A nrPDB Length = 393 Score = 127 bits (319), Expect = 9e-30, Method: Compositional matrix adjust. Identities = 99/334 (29%), Positives = 157/334 (47%), Gaps = 15/334 (4%) Query: 58 FAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDV 117 F+ Y ++ + PG+NI FSP SI AM LGA + + +Q+ +GLG L+ SD Sbjct: 17 FSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQGLG-----LASSDP 71 Query: 118 HRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVG 177 + L R+ + +F+ + +F + + +F V Sbjct: 72 EQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFLSAAQSVDFSKNVQ 131 Query: 178 TIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYV 235 IN+ V++ T I DLV L + +VLVN I+FK W+ F T P F++ Sbjct: 132 AAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQFAKHLTRPDTFHL 191 Query: 236 DENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYK-GDATVFFILPN-QGKMREIEEVL 293 D TV+VPMM +E Y L L + YK D ++ +LPN + + +EE L Sbjct: 192 DGERTVQVPMM-SLKERFRYADLPALDAMALELPYKDSDLSMLIVLPNTKTGLPALEEKL 250 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 L + L + K+ L LP+F L ++ +LG + +FS A+ + + Sbjct: 251 RLTTLSQITQSL----YETKVALKLPRFKAEFQVELSEVFQKLGMSRMFSDQAEFGKMLQ 306 Query: 354 Q-QKLEASKSFHKATLDVDEAGTEAAAATSFAIK 386 + L+ S HKA ++V+E GTEAAAAT A++ Sbjct: 307 SPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVR 340 >3LE2-A nrPDB Length = 393 Score = 125 bits (313), Expect = 4e-29, Method: Compositional matrix adjust. Identities = 105/375 (28%), Positives = 178/375 (47%), Gaps = 19/375 (5%) Query: 64 YLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQH 123 ++I + + N+ FSP SI+ ++++ G+ ++ QIL L F+ T+ S Sbjct: 22 HVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSSTDQLNSFSSEIVSA 81 Query: 124 LLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYD-TVGTIQLI 182 +L + G G + V + ++ +L F F Y+A +F V I + Sbjct: 82 VLADGSANG-GPKLSVANGAWIDKSLSFKPSFKQLLEDSYKAASNQADFQSKAVEVIAEV 140 Query: 183 NDHVKKETRGKIVDLVSELKKDVL--MVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240 N +KET G I +++ E D + ++ N +YFK W + F S T +F++ + Sbjct: 141 NSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGNK 200 Query: 241 VRVPMMLQDQEHHWYLHD--RYLPCSVLRMDYKGDATVFFILP--NQGKMREIEEVL-TP 295 V P M ++ + +D + L L+ K +++F LP N G +++++ TP Sbjct: 201 VTAPFMTSKKKQYVSAYDGFKVLGLPYLQGQDKRQFSMYFYLPDANNGLSDLLDKIVSTP 260 Query: 296 EMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQ- 354 L +N + +R K E +PKF S + +L LG T FS L+ + + Sbjct: 261 GFL---DNHIPRRQ-VKVREFKIPKFKFSFGFDASNVLKGLGLTSPFSGEEGLTEMVESP 316 Query: 355 ---QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NRPFLVVIFS 409 + L S FHKA ++V+E GTEAAAA++ IK + F + PFL+V+ Sbjct: 317 EMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIKLRGLLMEEDEIDFVADHPFLLVVTE 376 Query: 410 TSTQSVLFLGKVVDP 424 T VLF+G+VVDP Sbjct: 377 NITGVVLFIGQVVDP 391 >5NCS-A nrPDB Length = 375 Score = 123 bits (309), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 113/383 (29%), Positives = 177/383 (46%), Gaps = 26/383 (6%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGL-- 105 S KI NA FAF N+F SPLS+S A M GA + ++ L Sbjct: 5 SEKIEKDNA-FAFDLLQTTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRE 63 Query: 106 -GFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAK--FLNDTMAV 162 G+ + +++E + H L L T +G A + + L K F+ Sbjct: 64 TGYTMEDINE------YSHSLREALLKVDP-STTIGMANSIWYKQGELVKEPFILANRTH 116 Query: 163 YEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKP 222 Y+A++ +F + T+ IN ++T KI ++ + + M L+N +YFK +W Sbjct: 117 YDAEVKAVDF-SSPATLPAINGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQ 175 Query: 223 FISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA-TVFFILP 281 F S T F + TT V MM Q + Y D C L MDY A ++ +LP Sbjct: 176 FKKSDTKRAPFRKADGTTQEVNMMAQ-KSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLP 232 Query: 282 NQGK-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLD-QILPRLGFT 339 N+G+ R++ E L + W+ +++ ++ L +P+F Y L+ +ILP +G Sbjct: 233 NEGQTTRDVIEQLDNK---HWSMIIKGIR-PTQVSLRMPRFKTECKYGLEKKILPEMGMN 288 Query: 340 DLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFA-IKFFSAQTNRHILR 398 F++ AD GIT + S+ HK + VDE GTEAAA T+ +K S T Sbjct: 289 VPFTETADFPGIT-DAAIFISRVIHKTFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFH 347 Query: 399 FNRPFLVVIFSTSTQSVLFLGKV 421 N+PF+ I ST +LF+G++ Sbjct: 348 INKPFVFAIREKSTGVILFIGEI 370 >3ZHA-A nrPDB Length = 392 Score = 119 bits (298), Expect = 3e-27, Method: Compositional matrix adjust. Identities = 95/380 (25%), Positives = 183/380 (48%), Gaps = 19/380 (5%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +A +A AF Y +A + +NI SP+ ++++ ++SLG + + SQ L + Sbjct: 9 LAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLGGKATTASQAKAVL--SAE 66 Query: 111 ELSESDVHRGFQHLLHTL-NLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 +L + +VH G LL +L N + ++GS L+ ++ F F+ + Y + Sbjct: 67 QLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFAEDFVRSSKQHYNCEHSK 126 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 NF D +Q IN+ + T GK+ ++ ++++ +LVN ++FK W++ F Sbjct: 127 INFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVD 186 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATVFFILPNQGK-MR 287 + F V + TV V MM + +++Y D ++ M +++ ++P+ + + Sbjct: 187 NRGFMVTRSYTVGVTMMHRTGLYNYY-DDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLE 245 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK-WA 346 +E++LT E L W ++K K + + LPK + ++ L + L LG T+ K A Sbjct: 246 RLEKLLTKEQLKIWMGKMQK----KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKA 301 Query: 347 DLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NRPFL 404 DLS ++ ++ L + FH + D G F + + R F + PF+ Sbjct: 302 DLSRMSGKKDLYLASVFHATAFEWDTEG------NPFDQDIYGREELRSPKLFYADHPFI 355 Query: 405 VVIFSTSTQSVLFLGKVVDP 424 ++ T + S+LF+G++V P Sbjct: 356 FLVRDTQSGSLLFIGRLVRP 375 >2R9Y-A nrPDB Length = 430 Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 109/376 (28%), Positives = 171/376 (45%), Gaps = 21/376 (5%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 ++A A F + L+A + N+ SPLS++ A + L+LGA ++Q L L L Sbjct: 20 RLAQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGA----QNQTLHSLHRVL 75 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 + S + H L PG R+ + ++L FL + ++ AK Sbjct: 76 HMNTGSCLPHLLSHFYQNLG-PG---TIRLAARIYLQKGFPIKDDFLEQSERLFGAKPVK 131 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 + IN VK+ T GKI D +SEL +++L+N I+F W F S T Sbjct: 132 LTGKQE-EDLANINQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKFDPSLTQ 190 Query: 230 PKDFYVDENTTVRVPMM-LQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMRE 288 F++DE TV V MM W+L ++ V +K + + ++P + Sbjct: 191 KDFFHLDERFTVSVDMMHAVSYPLRWFLLEQP-EIQVAHFPFKNNMSFVVVMPTYFEWN- 248 Query: 289 IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL 348 + EVL + W+ L + ++ LPK + L L +LG +LF + DL Sbjct: 249 VSEVLAN---LTWDTLYHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQELF-QGPDL 304 Query: 349 SGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIF 408 GI+ +Q L S H++T+++ EAG EAAAATS A+ S + NRPFL I Sbjct: 305 RGIS-EQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLSS----FTVNRPFLFFIM 359 Query: 409 STSTQSVLFLGKVVDP 424 + LF+G V +P Sbjct: 360 EDTIGVPLFVGSVRNP 375 >4DY0-A nrPDB Length = 379 Score = 118 bits (296), Expect = 4e-27, Method: Compositional matrix adjust. Identities = 103/394 (26%), Positives = 182/394 (46%), Gaps = 52/394 (13%) Query: 56 ADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQI-------LEGLGFN 108 ++ + + I P NI SP I++ ML LGA ++ Q+ + G+G Sbjct: 13 SNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRYGVNGVGKI 72 Query: 109 LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLF 168 L +++++ V + + ++ V +A+F+ + + F+ V++ ++ Sbjct: 73 LKKINKAIVSKKNKDIV------------TVANAVFVKNASEIEVPFVTRNKDVFQCEVR 120 Query: 169 HTNFYDTVGTIQLINDHVKKETRGKIVDLVS-ELKKDVL--MVLVNYIYFKALWEKPFIS 225 + NF D IN VK ETR I +L+S +L VL +VLVN +YFK LW+ F Sbjct: 121 NVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQP 180 Query: 226 SRTTPKDFYVDENTTVRVPMMLQ----------DQEHHWYLHDRYLPCSVLRMDYKGDAT 275 T + F + + +VPM+ Q WY + + + Y G++ Sbjct: 181 ENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWY--------NFIELPYHGESI 232 Query: 276 VFFI-LPNQGK--MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQI 332 I LP + + I ++ + + W +++ K++++ LPKF+ L + Sbjct: 233 SMLIALPTESSTPLSAIIPHISTKTIDSWMSIM----VPKRVQVILPKFTAVAQTDLKEP 288 Query: 333 LPRLGFTDLF-SKWADLSGITK-QQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSA 390 L LG TD+F S A+ + IT + L S KA ++V E GT+A+AAT+ A Sbjct: 289 LKVLGITDMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATT---AILIA 345 Query: 391 QTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 +++ +RPFL I T +VLF+G++ P Sbjct: 346 RSSPPWFIVDRPFLFFIRHNPTGAVLFMGQINKP 379 >1K9O-I nrPDB Length = 378 Score = 117 bits (294), Expect = 8e-27, Method: Compositional matrix adjust. Identities = 107/384 (27%), Positives = 190/384 (49%), Gaps = 32/384 (8%) Query: 54 ANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF---NLT 110 +N F + + + PG+N+ S S+ L+L + S ++L L N+T Sbjct: 14 SNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALALPNDNVT 73 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 + +D++RG + + G++ ++ S ++++ L+ F + V+ +++ + Sbjct: 74 KDVFADLNRGVRAV--------KGVDLKMASKIYVAKGLELNDDFAAVSRDVFGSEVQNV 125 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRT 228 +F +V IN V+ +T +I +LV L + VLVN IYFK W+ F+ RT Sbjct: 126 DFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFVKERT 185 Query: 229 TPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATVFFILPNQ-GKM 286 +DF+V ++ T++VP M+ ++ Y L ++ M Y+GD A++ ILPNQ + Sbjct: 186 MDRDFHVSKDKTIKVPTMIGKKDVR-YADVPELDAKMIEMSYEGDQASMIIILPNQVDGI 244 Query: 287 REIEEVLT-PEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 +E+ L P+ L R +R + ++E+ LPKF I + L ++L + LF+ Sbjct: 245 TALEQKLKDPKALSR----AEERLYNTEVEITLPKFKIETTTDLKEVLSNMNIKKLFTPG 300 Query: 346 -ADLSGITK-QQKLEASKSFHKATLDVDEAGTEAAAATSFAI--KFFSAQTNRHILRFNR 401 A L + K ++ L + KA ++V+E G EAAAA +F I K HI +R Sbjct: 301 AARLENLLKTKESLTVDAAIQKAFIEVNEEGAEAAAANAFGIVPKSLILYPEVHI---DR 357 Query: 402 PFLVVIFSTSTQSV-LFLGKVVDP 424 PF F + +F GKV++P Sbjct: 358 PFY---FELKIDGIPMFNGKVIEP 378 >4DTE-A nrPDB Length = 374 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 93/387 (24%), Positives = 176/387 (45%), Gaps = 27/387 (6%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 I DF + + P +N+ SP I++ M +GA + + +G++L Sbjct: 3 IQDKQTDFGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQ 62 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E + R Q L + + G+E V S + + + F +++ Sbjct: 63 ERGMPKLQRLLQRDLASED----GVE--VASGVMVDRKIILEKVFRRSLSKAFQSVPHQI 116 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVD-----LVSELKKDVLMVLVNYIYFKALWEKPFIS 225 +F Q+IN T G I + ++SEL + +V +N ++F +W+ PF Sbjct: 117 DFSQPEMARQVINSWTSDHTDGMISEFLPSGVLSELTR---LVFLNALHFHGVWKTPFDP 173 Query: 226 SRTTPKDFYVDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGDA-TVFFILPN 282 T + F+ + V VPMM Q+ ++ ++ + V+ M Y+G++ ++ + P Sbjct: 174 RNTREQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVTPF 233 Query: 283 QGK--MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTD 340 + + + + L+ + +W +RK + +L +P+FS+ L L R+G D Sbjct: 234 EKDVPLSALNKELSSSRIHQWRQEMRKIS----KQLSIPRFSMDTEIDLKSTLSRMGLGD 289 Query: 341 LFSK-WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF 399 +FS+ AD S IT ++ L SK + L+V+E GT+ ++AT+ I +S I Sbjct: 290 IFSQSRADFSRITTEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVI--YSRMAVEEIT-L 346 Query: 400 NRPFLVVIFSTSTQSVLFLGKVVDPTK 426 +RPF +I T ++LF G++ P + Sbjct: 347 DRPFFFLIQHKPTGALLFSGQLTQPQE 373 >1SEK-A nrPDB Length = 378 Score = 115 bits (287), Expect = 4e-26, Method: Compositional matrix adjust. Identities = 80/301 (26%), Positives = 150/301 (49%), Gaps = 21/301 (6%) Query: 54 ANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF---NLT 110 +N F + + + PG+N+ S S+ L+L + S ++L L N+T Sbjct: 14 SNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELLRALALPNDNVT 73 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 + +D++RG + + G++ ++ S ++++ L+ F + V+ +++ + Sbjct: 74 KDVFADLNRGVRAV--------KGVDLKMASKIYVAKGLELNDDFAAVSRDVFGSEVQNV 125 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRT 228 +F +V IN V+ +T +I +LV L + VLVN IYFK W+ F RT Sbjct: 126 DFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKGSWKDKFNKERT 185 Query: 229 TPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATVFFILPNQ-GKM 286 +DF+V ++ T++VP M+ ++ Y L ++ M Y+GD A++ ILPNQ + Sbjct: 186 MDRDFHVSKDKTIKVPTMIGKKDVR-YADVPELDAKMIEMSYEGDQASMIIILPNQVDGI 244 Query: 287 REIEEVLT-PEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 +E+ L P+ L R +R + ++E++LPKF I + L ++L + LF+ Sbjct: 245 TALEQKLKDPKALSR----AEERLYNTEVEIYLPKFKIETTTDLKEVLSNMNIKKLFTPG 300 Query: 346 A 346 A Sbjct: 301 A 301 >6CJ7-A nrPDB Length = 390 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 107/390 (27%), Positives = 175/390 (44%), Gaps = 38/390 (9%) Query: 52 APANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN--- 108 PA+ F + +A+E G N+ SP SI+ AML GA ++ +I L Sbjct: 14 GPASTSFGVNVFKQMATEQSG-NLAASPFSITILLAMLQQGAAGNTLDEITRALQMTPEK 72 Query: 109 ----LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 +++E R +++L T N +FLS N +F + ++ Sbjct: 73 SAEIFKKVNEEIQKRNSRNILKTAN------------NVFLSENFNLNPQFKRIAVNNFD 120 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKP 222 + L T F Q IN + +T KI LVS +L + MV+VN +YFK LWE P Sbjct: 121 SDLTPTYFGKPALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMVNAVYFKGLWEIP 180 Query: 223 FISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPC----SVLRMDYKGDATVFF 278 F T ++F ++ M Q ++ + P VL +Y + ++ Sbjct: 181 FREQATQKRNFTLNGGEKKVASFM---QTRRYFKAGTHKPAMAKVVVLPFEY-NEYSLIV 236 Query: 279 ILP-NQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLG 337 +LP + + L+ E + + +L K + L LPKFSI L+ +L ++G Sbjct: 237 VLPLKSSNVDALLSSLSMEDVASFLDLPP-----KDVALELPKFSIKADINLEPVLNKMG 291 Query: 338 FTDLFSKWADLSGITKQQKL--EASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRH 395 + +F++ A+L + L + S + H A L +DE G AAAATSFA S Sbjct: 292 VSSIFTQQAELYNLGSHGSLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYDEPSL 351 Query: 396 ILRFNRPFLVVIFSTSTQSVLFLGKVVDPT 425 R N+PFL +++ + LF+ +++DPT Sbjct: 352 YFRANKPFLAILWDNRSSIPLFMARIMDPT 381 >1C8O-A nrPDB Length = 300 Score = 112 bits (280), Expect = 3e-25, Method: Compositional matrix adjust. Identities = 96/321 (29%), Positives = 148/321 (46%), Gaps = 33/321 (10%) Query: 66 IASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLL 125 IAS G+N+F SP SIS+ +L GA + Q L++ E + + + Sbjct: 7 IASSMKGENVFISPPSISSVLTILYYGANGSTAEQ--------LSKYVEKEADKNKDDIS 58 Query: 126 HTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDH 185 +G SA+F FL K ++ F T + T+ IN Sbjct: 59 FKSMNKVYGRY----SAVFKDS---FLRKIGDN---------FQTVDFTDSRTVDAINKS 102 Query: 186 VKKETRGKIVDLVSE-LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVP 244 V T GKI L+ E L D ++ ++ +YFKA W PF T+ FYV V V Sbjct: 103 VDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVS 162 Query: 245 MMLQDQE--HHWYLHDRYLPCSVLRMDYKGDATVFFILP-NQGKMREIEEVLTPEMLMRW 301 MM E +H + + + S++ + Y GD ++ ILP N + IE+ LT +W Sbjct: 163 MMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTNFKKW 222 Query: 302 NNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASK 361 ++ + +++H+PKF ++GSY L L +LG T++F D S ++ + Sbjct: 223 SDSMDAM----FIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNSD-VSVDA 277 Query: 362 SFHKATLDVDEAGTEAAAATS 382 HK +DV+E TEAAAATS Sbjct: 278 MIHKTYIDVNEEYTEAAAATS 298 >1JJO-C nrPDB Length = 261 Score = 109 bits (273), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 74/253 (29%), Positives = 133/253 (52%), Gaps = 13/253 (5%) Query: 138 RVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDL 197 ++ ++LF+ + +FL + A++ H +F V IN V+ T + DL Sbjct: 7 KLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTNSLLKDL 66 Query: 198 VSELKKDVL--MVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHW- 254 VS D + + L+N +YFK W+ F T F D+ + V++PMM Q E ++ Sbjct: 67 VSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQGEFYYG 126 Query: 255 YLHDRYLPCS----VLRMDYKGDA-TVFFILPNQG-KMREIEEVLTPEMLMRWNNLLRKR 308 D VL + Y+GD ++ L Q + +E +L +++ W N ++K+ Sbjct: 127 EFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWANSVKKQ 186 Query: 309 NFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATL 368 K+E++LP+F++ L IL LG T++F K A+L+ ++ +++L SK+ HK+ + Sbjct: 187 ----KVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKELFLSKAVHKSCI 242 Query: 369 DVDEAGTEAAAAT 381 +V+E G+EAAAA+ Sbjct: 243 EVNEEGSEAAAAS 255 >5NCU-A nrPDB Length = 336 Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 101/343 (29%), Positives = 158/343 (46%), Gaps = 25/343 (7%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGL-- 105 S KI NA FAF N+F SPLS+S A M GA + ++ L Sbjct: 5 SEKIEKDNA-FAFDLLQTTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTALRE 63 Query: 106 -GFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAK--FLNDTMAV 162 G+ + +++E + H L L T +G A + + L K F+ Sbjct: 64 TGYTMEDINE------YSHSLREALLKVDP-STTIGMANSIWYKQGELVKEPFILANRTH 116 Query: 163 YEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKP 222 Y+A++ +F + T+ IN ++T KI ++ + + M L+N +YFK +W Sbjct: 117 YDAEVKAVDF-SSPATLPAINGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQ 175 Query: 223 FISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA-TVFFILP 281 F S T F + TT V MM Q + Y D C L MDY A ++ +LP Sbjct: 176 FKKSDTKRAPFRKADGTTQEVNMMAQ-KSTFGYTTDEC--CQYLEMDYGNKAFSMIVMLP 232 Query: 282 NQGK-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLD-QILPRLGFT 339 N+G+ R++ E L + W+ +++ ++ L +P+F Y L+ +ILP +G Sbjct: 233 NEGQTTRDVIEQLDNK---HWSMIIKGIR-PTQVSLRMPRFKTECKYGLEKKILPEMGMN 288 Query: 340 DLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATS 382 F++ AD GIT + S+ HK + VDE GTEAAA T+ Sbjct: 289 VPFTETADFPGIT-DAAIFISRVIHKTFVQVDEEGTEAAAVTA 330 >1XQJ-A nrPDB Length = 389 Score = 104 bits (260), Expect = 6e-23, Method: Compositional matrix adjust. Identities = 91/382 (23%), Positives = 179/382 (46%), Gaps = 24/382 (6%) Query: 54 ANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELS 113 AN+ FA + ++ + P N+ FSP+++S + ++ +GA + ++I + L F + Sbjct: 21 ANSAFAVDLFKQLSEKEPLGNVLFSPIALSTSLSLAQVGAKGDTANEIGQVLHFENVK-- 78 Query: 114 ESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY 173 DV GFQ + +N ++ L++ +L +F++ T Y +L +F Sbjct: 79 --DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETVDFK 136 Query: 174 DTV-GTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 D + T IN+ +K T G +++++ + +++VN YF W K F S T Sbjct: 137 DKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESETKE 196 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHD-RYLPCSVLRMDYKGD-ATVFFILPNQGK--- 285 F V++ T V MM + E + + + + ++ + ++ ++F +LP + Sbjct: 197 SPFRVNKTDTKPVQMM--NMEATFSMGNIDSINSKIIELPFQNKHLSMFILLPKDVEDES 254 Query: 286 --MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 + +IE+ L E L +W N N K++L +PKF + L LG +FS Sbjct: 255 TGLEKIEKQLNSESLSQWTNPSTMAN--AKVKLSIPKFKVEKMIDPKASLENLGLKHIFS 312 Query: 344 K-WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRP 402 + +D SG+++ + + S HK +L++ E G ++ I ++ L + P Sbjct: 313 EDTSDFSGMSETKGVALSNVIHKVSLEITEDGGDSIEVPGARI-----LQHKDELNADHP 367 Query: 403 FLVVIFSTSTQSVLFLGKVVDP 424 F+ +I T++++F GK P Sbjct: 368 FIYIIRHNKTRNIIFFGKFSSP 389 >1M93-B nrPDB Length = 245 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 70/209 (33%), Positives = 107/209 (51%), Gaps = 9/209 (4%) Query: 178 TIQLINDHVKKETRGKIVDLVSE-LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVD 236 T+ IN V T GKI L+ E L D ++ ++ +YFKA W PF T+ FYV Sbjct: 40 TVDAINKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVS 99 Query: 237 ENTTVRVPMMLQDQE--HHWYLHDRYLPCSVLRMDYKGDATVFFILP-NQGKMREIEEVL 293 V V MM E +H + + + S++ + Y GD ++ ILP N + IE+ L Sbjct: 100 PTEMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNL 159 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 T +W++ + +++H+PKF ++GSY L L +LG T++F D S ++ Sbjct: 160 TDTNFKKWSDSMDAM----FIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSN 215 Query: 354 QQKLEASKSFHKATLDVDEAGTEAAAATS 382 + HK +DV+E TEAAAATS Sbjct: 216 SD-VSVDAMIHKTYIDVNEEYTEAAAATS 243 >3PZF-A nrPDB Length = 397 Score = 103 bits (258), Expect = 1e-22, Method: Compositional matrix adjust. Identities = 81/314 (25%), Positives = 146/314 (46%), Gaps = 18/314 (5%) Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180 ++ LL + + + + F+ ++ + K+ Y A L ++ + T Sbjct: 90 YKQLLESAQQDNKDYDLNIATNFFVDDFIEVINKYQQIANTHYHAMLEKVSYSNPTQTAA 149 Query: 181 LINDHVKKETRGKIVDLVS-ELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENT 239 IN+ V + T G++ ++V+ + + ++ LVN IYFK LW PF K FY Sbjct: 150 TINNWVSEHTNGRLREIVTPDSLEGAVITLVNVIYFKGLWTYPFPEVANNVKPFYGTRGK 209 Query: 240 TVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA-TVFFILPNQGKMREIEEVLTPEML 298 M Q+ + +Y + L +LR+ Y+G+ ++FILPN ++L Sbjct: 210 PTNAQYMEQNGQ-FYYDNSADLGAQILRLPYRGNKLAMYFILPNPDNT-------VNQVL 261 Query: 299 MRWNNL-LRKRNFY---KKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL----SG 350 R N+ L + +Y ++ + LPKF S L++ L ++G ++FS+ A L G Sbjct: 262 DRINSASLHQALWYMEENEVNVTLPKFKFDFSEQLNEPLQQVGIREIFSQNASLPLLARG 321 Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFST 410 + ++ S+ F KA + ++E G+EA AAT + I NRPF+ I Sbjct: 322 RGARDEVRVSRIFQKAGITINELGSEAYAATEIQLVNKFGGDGVQIFNANRPFIFFIEDE 381 Query: 411 STQSVLFLGKVVDP 424 + ++LF GK+ +P Sbjct: 382 TLGTMLFAGKIENP 395 >2OAY-A nrPDB Length = 390 Score = 100 bits (250), Expect = 1e-21, Method: Compositional matrix adjust. Identities = 99/378 (26%), Positives = 177/378 (46%), Gaps = 31/378 (8%) Query: 54 ANADFAFRFYYLI-ASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTEL 112 A DF+ + Y+ A + N+ FSP SI++ + LGA ++++ + L + Sbjct: 35 ALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPKDFT 94 Query: 113 SESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEA--KLFHT 170 +GF G+ + S +F S +L F+N + +Y + ++ Sbjct: 95 CVHQALKGFT---------TKGVTSV--SQIFHSPDLAIRDTFVNASRTLYSSSPRVLSN 143 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 N + ++LIN V K T KI L+ L D +VL+N IY A W+ F +T Sbjct: 144 N---SDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTRM 200 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR--E 288 + F+ +N+ ++VPMM + + D+ L V ++ + ++ ++P K R + Sbjct: 201 EPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLED 259 Query: 289 IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL 348 +E+ L+P + L F L L LP+ ++ S + I+ +L F D FS +L Sbjct: 260 MEQALSPSVFKAIMEKLEMSKFQPTL-LTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLNL 317 Query: 349 SGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NRPFLVV 406 G+T+ L+ S H+ L++ E G EAAAA+ + R +L F +PFL + Sbjct: 318 CGLTEDPDLQVSAMQHQTVLELTETGVEAAAAS-------AISVARTLLVFEVQQPFLFM 370 Query: 407 IFSTSTQSVLFLGKVVDP 424 ++ + +F+G+V DP Sbjct: 371 LWDQQHKFPVFMGRVYDP 388 >2PEF-A nrPDB Length = 373 Score = 94.7 bits (234), Expect = 7e-20, Method: Compositional matrix adjust. Identities = 97/371 (26%), Positives = 161/371 (43%), Gaps = 18/371 (4%) Query: 56 ADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSES 115 ADF+ + S +N SPLS A AM + GA + + +Q+ + LG ++S Sbjct: 14 ADFSIELFK--NSIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALG---KDISIE 68 Query: 116 DVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDT 175 D+++ + L T S F ++ FL Y+A +F F Sbjct: 69 DLNKYLYTYMKKLPNEEKSKLTIANSIWFKENDFMPSKDFLQIIADYYKADIFKAAF--D 126 Query: 176 VGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYV 235 T+ IN+ VK +T G I +++++ + +M L+N + F A WE + + +D + Sbjct: 127 SSTVSDINNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDAEWETVY-EKASVHEDIFT 185 Query: 236 DENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG-KMREIEEVLT 294 D R + + E + Y+ + ++ K + ILP++ + E + LT Sbjct: 186 DVYGN-RQKVEFMNSEENLYIEEEN-AVGFVKPYAKNHYSFVAILPDENISVNEYIKTLT 243 Query: 295 PEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLF-SKWADLSGITK 353 + + L K + LPKF + +++ L LG TD F AD S + K Sbjct: 244 GQKFID----LIKNAKITLVRASLPKFKYEYTIKMNETLESLGMTDAFLPDKADFSKLGK 299 Query: 354 QQ--KLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTS 411 L S+ HK + VDE GT+A A TS I N ++ NRPF+ I S Sbjct: 300 SDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNFKTVKLNRPFIFAIIDNS 359 Query: 412 TQSVLFLGKVV 422 T +F+G V+ Sbjct: 360 TNLPIFIGTVL 370 >3OZQ-A nrPDB Length = 376 Score = 92.4 bits (228), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 92/318 (28%), Positives = 150/318 (47%), Gaps = 18/318 (5%) Query: 69 ETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF-NLTELSESDVHRGFQHLLHT 127 +T N SP S + A+ G + +I + L F E +E V + +L Sbjct: 28 KTEKANFLVSPFSAATLLALAQSGCRGDTAEEIRQVLHFVGDREKAEGAV----KEVLSK 83 Query: 128 LNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVK 187 L + L T + +++ N +F + VY A+ + +F + +L+N V+ Sbjct: 84 LTNEEYTLHT--ANKIYVKTNFSVREEFQKIAVEVYGAQSENVDFSEKNDAAKLMNAWVE 141 Query: 188 KETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPM 245 ++T+ KI +LV L +VL+N +YF A W PF T DF+ V+V Sbjct: 142 EQTQHKIQNLVDPEILNNLTRVVLINALYFNAKWLVPFPPFHTRKSDFHKSAKEVVQVDT 201 Query: 246 MLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLL 305 M D+++ Y +L +L + +KG A++ +L NQ IE +++ E ++ + L Sbjct: 202 MYLDEQYFNYYECHHLDAKLLELPFKGGASLTIVLSNQ-----IEGLVSLESKIKRSFL- 255 Query: 306 RKRNFYKKL-ELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQ-KLEASKSF 363 N K+L + LPKF I + ++L +LG F ADLSGI ++ L S Sbjct: 256 -PHNLTKQLVNVALPKFKIESTVDFKKVLKKLGVKKAFGDEADLSGIAGEKGDLVISNIV 314 Query: 364 HKATLDVDEAGTEAAAAT 381 K+ +DV E G EAAAAT Sbjct: 315 QKSFIDVSEEGVEAAAAT 332 >3STO-A nrPDB Length = 406 Score = 80.9 bits (198), Expect = 9e-16, Method: Compositional matrix adjust. Identities = 71/291 (24%), Positives = 123/291 (42%), Gaps = 8/291 (2%) Query: 138 RVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDL 197 R+ + +F+ + +F E +L +F + IND V +++ G + Sbjct: 116 RISTGIFVEKTYEVERRFNESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLEKF 175 Query: 198 VSE-LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYL 256 ++ + D M+LVN YF+ W+ PF T +DFY+ + + V MM Q+ + Sbjct: 176 FTDDIPDDTAMILVNVFYFRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGK 235 Query: 257 HDRYLPCSVLRMDYKGDATVFFILP-NQGKMREIEEVLTP-EMLMRWNNLLRKRNFYKKL 314 + V + T +LP + + E+L ++L + L++ + Sbjct: 236 FEDEGFEIVSKPLNNTRFTFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKETT----V 291 Query: 315 ELHLPKFSISGSYVLDQILPRLGFTDLFSKW-ADLSGITKQQKLEASKSFHKATLDVDEA 373 L LPKF++ + L L +G DLF +DLSGIT L ++ L ++E+ Sbjct: 292 SLRLPKFTLKNTLDLVPTLKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNES 351 Query: 374 GTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 G EA TS FSA PF+ I+ + KV++P Sbjct: 352 GIEATTVTSPIFVPFSAIIPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNP 402 >1SNG-A nrPDB Length = 370 Score = 79.3 bits (194), Expect = 3e-15, Method: Compositional matrix adjust. Identities = 95/376 (25%), Positives = 165/376 (43%), Gaps = 30/376 (7%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 +FA + +A P + +SP S++ A +L+ GA + +R+++ LG + L + Sbjct: 16 EFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAPLLAA- 74 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY-DT 175 L L +R + L++S ++ + F ++ + +F + Sbjct: 75 --------LDRAVTDSPDLASR--TVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNP 124 Query: 176 VGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDF 233 G +N + TRG I +L+ + + D+ +L N ++ KA W PF + T F Sbjct: 125 EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTRAGTF 184 Query: 234 YVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVL 293 RVP M + + + + ++ + + V +LP V Sbjct: 185 RTPRGPK-RVPFMHRTKTMPYATARGW---RMVTLHAHDELAVDVLLPPGTNA---AAVP 237 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 T +L L +R+ +EL LP+F ++ + L ++L G LF+ ADLSGI+ Sbjct: 238 TAPLL----TALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGIS- 292 Query: 354 QQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NRPFLVVIFSTS 411 L H+A L VDE G E AAAT+ + A R +RF +RPF +V+ Sbjct: 293 TVPLYVDTVIHQARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRRG 352 Query: 412 TQSVLFLGKVVDPTKP 427 ++LFLG + DP P Sbjct: 353 --AILFLGSIADPHDP 366 >6BJ5-B nrPDB Length = 315 Score = 68.9 bits (167), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 79/330 (23%), Positives = 139/330 (42%), Gaps = 40/330 (12%) Query: 58 FAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDV 117 + FR+ Y N+ FSP +++A ++L + A +++ +I + + +SD Sbjct: 21 WTFRYVY-----NESDNVVFSPYGLTSALSVLRIAAGGNTKREI----DVPESVVEDSDA 71 Query: 118 HRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVG 177 + L ++P L +F ++F +V N D Sbjct: 72 FLALRELFVDASVP-----------LRPEFTAEFSSRF---NTSVQRVTFNSENVKD--- 114 Query: 178 TIQLINDHVKKETRGKIVDLV-SELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVD 236 +IN +VK +T G + ++ + L +D M+L++ + K W F S TT + FY Sbjct: 115 ---VINSYVKDKTGGDVPRVLDASLDRDTKMLLLSSVRMKTSWRHVFDPSFTTDQPFY-S 170 Query: 237 ENTTVRVPMMLQ-DQEHHWYLHDRYLPCSVLRMDYKGDAT-VFFILPNQGKMREIEEVLT 294 N T +V MM + D R + SV + YK T + ++P+ + EI L Sbjct: 171 GNVTYKVRMMNKIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPDD--LGEIVRALD 228 Query: 295 PEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS-KWADLSGITK 353 ++ W +RK ++ +PKFS+ L L RLG D F AD + Sbjct: 229 LSLVRFWIRNMRK----DVCQVVMPKFSVESVLDLRDALQRLGVRDAFDPSRADFGQASP 284 Query: 354 QQKLEASKSFHKATLDVDEAGTEAAAATSF 383 L +K + ++ DE GT A++ T+ Sbjct: 285 SNDLYVTKVLQTSKIEADERGTTASSDTAI 314 >1MTP-A nrPDB Length = 323 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 74/319 (23%), Positives = 135/319 (42%), Gaps = 26/319 (8%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 +FA + +A P + +SP S++ A +L+ GA + +R+++ LG + L + Sbjct: 12 EFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAPLLAA- 70 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY-DT 175 L L +R + L++S ++ + F ++ + +F + Sbjct: 71 --------LDRAVTDSPDLASR--TVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNP 120 Query: 176 VGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDF 233 G +N + TRG I +L+ + + D+ +L N ++ KA W PF + T F Sbjct: 121 EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTREGTF 180 Query: 234 YVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVL 293 RVP M + + + + ++ + + V +LP V Sbjct: 181 RTPRGPK-RVPFMHRTKTMPYATARGW---RMVTLHAHDELAVDVLLPPGTNA---AAVP 233 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 T +L L +R+ +EL LP+F ++ + L ++L G LF+ ADLSGI+ Sbjct: 234 TAPLL----TALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGIST 289 Query: 354 QQKLEASKSFHKATLDVDE 372 L H+A L VDE Sbjct: 290 -VPLYVDTVIHQARLRVDE 307 >5M3Y-A nrPDB Length = 458 Score = 53.5 bits (127), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 78/369 (21%), Positives = 152/369 (41%), Gaps = 42/369 (11%) Query: 77 FSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---LSESDVHR---GFQHLLHTLNL 130 SP ++ A L LGA H+ ++ LG + S D H+ Q + L Sbjct: 101 LSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLVA 160 Query: 131 PGHG-------LETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLF--HTNFYDTVGTIQL 181 G L T VG +F + L F+ +A+Y + +F + + Sbjct: 161 QGRADSQAQLLLSTVVG--VFTAPGLHLKQPFVQG-LALYTPVVLPRSLDFTELDVAAEK 217 Query: 182 INDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTV 241 I+ ++ T K + D + Y++F+ + S P++F+VD++T+V Sbjct: 218 IDRFMQAVTGWKTGSSLMGASVDSTLAFNTYVHFQGKMKG--FSLLAEPQEFWVDQSTSV 275 Query: 242 RVPMML-QDQEHHWY-LHDRYLPCSVLRMDYKGDATVFFILPN-QGKMREIEEVLTPEML 298 VPM+ HW + D++ SV ++ + A++ I P+ + ++E + + Sbjct: 276 SVPMLSGMGTFQHWSDIQDQF---SVTQVPFTESASLLLIQPHYASDLDKVEGLTFQQNS 332 Query: 299 MRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLE 358 + W L R + L +P+ + GSY L +L + + +L ++ ++ Sbjct: 333 LNWMKKLSPRTIH----LTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSND-RIR 387 Query: 359 ASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNR-HILR--FNRPFLVVIFSTSTQSV 415 + + +++ E +T Q N+ +L NRPFL ++ S ++ Sbjct: 388 VGEVLNSIFFELEADEREPTESTQ--------QLNKPEVLEVTLNRPFLFAVYDQSATAL 439 Query: 416 LFLGKVVDP 424 FLG+V +P Sbjct: 440 HFLGRVANP 448 >2WXZ-C nrPDB Length = 453 Score = 52.0 bits (123), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 92/389 (23%), Positives = 153/389 (39%), Gaps = 41/389 (10%) Query: 58 FAFRFYYLIASETPG--KNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---L 112 FR Y ++ SE G SP ++ LG+ + SQ+ LG + E Sbjct: 80 MGFRMYKML-SEARGVASGAVLSPPALFGTLVSFYLGSLDPTASQLQVLLGVPVKEGDCT 138 Query: 113 SESDVHRGFQHLLHTLNLPGHGLETRVGSA------------LFLSHNLKFLAKFLNDTM 160 S D H+ L L L T+ GS+ LF + L+ F+ +++ Sbjct: 139 SRLDGHKVLTALQAVQGL----LVTQGGSSSQTPLLQSTVVGLFTAPGLRLKQPFV-ESL 193 Query: 161 AVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 217 + +F + D V Q IN V+ T K+ + + D + Y++F+ Sbjct: 194 GPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEGVSTDSTLFFNTYVHFQG 253 Query: 218 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQE-HHWYLHDRYLPCSVLRMDYKGDATV 276 S T +F+VD +T+V VPM+ HW D SV R+ T+ Sbjct: 254 KMRG--FSQLTGLHEFWVDNSTSVSVPMLSGTGNFQHW--SDAQNNFSVTRVPLGESVTL 309 Query: 277 FFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPR 335 I P + +E ++ + W K + + L LP+ I GSY L +L + Sbjct: 310 LLIQPQCASDLDRVEVLVFQHDFLTW----IKNPPPRAIRLTLPQLEIRGSYNLQDLLAQ 365 Query: 336 LGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRH 395 + L A+L G + + L++ +AG E S A + S + Sbjct: 366 AKLSTLLGAEANL-GKMGDTNPRVGEVLNSILLEL-QAGEEEQPTES-AQQPGSPEVLDV 422 Query: 396 ILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 L + PFL I+ + ++ FLG+V +P Sbjct: 423 TL--SSPFLFAIYERDSGALHFLGRVDNP 449 >2WXX-A nrPDB Length = 453 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 89/386 (23%), Positives = 153/386 (39%), Gaps = 37/386 (9%) Query: 59 AFRFYYLIASETPGKN-IFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---LSE 114 FR Y ++ G + SP ++ LG+ + SQ+ L + E S Sbjct: 81 GFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSLDPTASQLQTLLDVPVKEGDCTSR 140 Query: 115 SDVH------RGFQHLLHTLNLPGHGLET----RVGSALFLSHNLKFLAKFLNDTMAVYE 164 D H R Q LL T G +T + LF + + F+ ++A++ Sbjct: 141 LDGHKVLAALRAVQGLLVTQG--GSSSQTPLLQSIVVGLFTAPGFRLKHSFVQ-SLALFT 197 Query: 165 AKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEK 221 LF + D V + IN +K T K+ + + D ++ Y++F+ Sbjct: 198 PALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEGVSTDSTLLFNTYVHFQGTMRG 257 Query: 222 PFISSRTTPKDFYVDENTTVRVPMMLQDQE-HHWYLHDRYLPCSVLRMDYKGDATVFFIL 280 S +F+VD + +V VPM+ HW D SV + AT+ I Sbjct: 258 --FSQLPGVHEFWVDNSISVSVPMISGTGNFQHW--SDAQNNFSVTCVPLGERATLLLIQ 313 Query: 281 PNQGKMREIEEVLTPEMLMRWNNLLR--KRNFYKKLELHLPKFSISGSYVLDQILPRLGF 338 P+ + +++ V E L+ N+LL + + + L LP+ I GSY L +L Sbjct: 314 PH--CISDLDRV---EALIFQNDLLTWIENPPPRAIRLTLPQLEIRGSYNLQDLLAEDKL 368 Query: 339 TDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILR 398 L A+L+ I + + L++ +AG E TS + + Sbjct: 369 PTLLGAEANLNNIGDTNP-RVGEVLNSILLEL-KAGEEEQPTTSVQQPGSPEALD---VT 423 Query: 399 FNRPFLVVIFSTSTQSVLFLGKVVDP 424 + PFL I+ + ++ FLG+V +P Sbjct: 424 LSSPFLFAIYEQDSGTLHFLGRVNNP 449 >5C98-A nrPDB Length = 382 Score = 47.4 bits (111), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 92/404 (22%), Positives = 145/404 (35%), Gaps = 54/404 (13%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLS--LGACSHSRSQIL 102 G P+ A A+ F Y A N SP + A +M GA Q+ Sbjct: 9 GDPTTDDAIVAANNKFTLEYFKACYDEKCNCAVSPYHVRLALSMFYPLAGAAVQEDFQVA 68 Query: 103 EGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAV 162 GL DVH + G + S + + L+ ++F Sbjct: 69 FGL--------PEDVHAAIEQQQRLAQQLHDGQHLKALSFVLVEETLRLDSEF------- 113 Query: 163 YEAKLFHTNFYDTVGTIQLIND--------HVKKETRGKIVDLVSELKKDVLMVLVNYIY 214 +LFH F TV + L +D + +I D + E L + Sbjct: 114 --ERLFHRTFQTTVEPVDLTDDIPSALAVNSFYQRANTEIEDFIGEGDVFSLPPCHKLML 171 Query: 215 FKALWEKPFISSRTTPKD-----FYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMD 269 F + ++ R P D F T RV M LH+ L C V+ M Sbjct: 172 FSGVSVLTPLAIRFNPADTALELFQFINAPTQRVSTMHTTAFVRRCLHNE-LRCKVVDMP 230 Query: 270 YKGDA--TVFFILPNQG-KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGS 326 + + ++ +LP G ++R+I +TP L + + L+ +L LPKF + Sbjct: 231 FDAASGLSMLVLLPYDGTELRQIVNSITPAHLAQIDERLQS----CWTDLKLPKFFVREK 286 Query: 327 YVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIK 386 Q L +LG+ +F + DL + + L V E+G+ A + Sbjct: 287 TDPKQTLGKLGYGGVF-EIDDLHVFHDSGRTRLNGFIQHCYLAVSESGSGIPAPPDTPSE 345 Query: 387 F-FSAQTNRHILRFNRPFLVVIFSTSTQSVLFLG---KVVDPTK 426 F F A NRPF+ +I T +VL +G K +DP + Sbjct: 346 FEFHA---------NRPFMFLIRRTMDGNVLQVGNFSKYIDPDE 380 >3MI6-A nrPDB Length = 745 Score = 30.4 bits (67), Expect = 1.7, Method: Compositional matrix adjust. Identities = 20/81 (24%), Positives = 33/81 (40%), Gaps = 5/81 (6%) Query: 38 QILETGEGS-----PSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLG 92 QI++ GE P + + P + + + +N F P +I A YA L G Sbjct: 24 QIMKNGEAGQIYYGPRIHVQPTYQNLMSQEWRDATPSLNEENPNFQPATIKAEYASLGKG 83 Query: 93 ACSHSRSQILEGLGFNLTELS 113 Q+ + G +TEL+ Sbjct: 84 DFRQPAFQVTQANGSRITELT 104 >3MOG-A nrPDB Length = 483 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 19/26 (73%), Gaps = 1/26 (3%) Query: 242 RVPMMLQDQEHHWYLHDRYLPCSVLR 267 R+ +L++ +HH Y +RY PCS+LR Sbjct: 440 RILRLLENLQHH-YGEERYRPCSLLR 464 >4OR8-A nrPDB Length = 267 Score = 29.3 bits (64), Expect = 3.0, Method: Compositional matrix adjust. Identities = 28/89 (31%), Positives = 48/89 (53%), Gaps = 9/89 (10%) Query: 100 QILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFL-ND 158 +IL G+ EL +S + GF+ ++H L+ L V SA+ +S NL L +L +D Sbjct: 109 RILLGVALKDQELQQSLI-PGFRSIVHMLS---EWLLLEVTSAIHISPNL--LGIYLTSD 162 Query: 159 TMAVYEAKLFHTNFYDTVGTIQLINDHVK 187 + A + NF++ + T+ ++NDH K Sbjct: 163 MFKILMAGV--KNFFNKMFTLHVVNDHGK 189 >1DGS-A nrPDB Length = 667 Score = 29.3 bits (64), Expect = 3.7, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 15/27 (55%) Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHG 134 NL E HRG + LL+ L LPG G Sbjct: 490 NLLRQIEESKHRGLERLLYALGLPGVG 516 >1V9P-A nrPDB Length = 584 Score = 28.9 bits (63), Expect = 4.0, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 15/27 (55%) Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHG 134 NL E HRG + LL+ L LPG G Sbjct: 493 NLLRQIEESKHRGLERLLYALGLPGVG 519 >3MWB-A nrPDB Length = 313 Score = 28.5 bits (62), Expect = 6.6, Method: Compositional matrix adjust. Identities = 13/52 (25%), Positives = 23/52 (44%) Query: 106 GFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLN 157 G NL+ + + H +++ GH ++RV AL H + +FL Sbjct: 227 GVNLSRIESRPTGQYLGHYFFSIDADGHATDSRVADALAGLHRISPATRFLG 278 >5LZS-jj nrPDB Length = 462 Score = 28.1 bits (61), Expect = 7.4, Method: Compositional matrix adjust. Identities = 13/50 (26%), Positives = 27/50 (54%) Query: 71 PGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120 PG + F+P++++ + + + S + + +GFN+ +S DV RG Sbjct: 274 PGMVVTFAPVNVTTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDVRRG 323 >4ERD-A nrPDB Length = 129 Score = 28.1 bits (61), Expect = 8.0, Method: Composition-based stats. Identities = 16/56 (28%), Positives = 28/56 (50%) Query: 183 NDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDEN 238 N+ ++ E RG+I D++S + +D NYI FK + F + K + +N Sbjct: 71 NNKLQIEIRGQICDVISTIPEDEEKNYWNYIKFKKNEFRKFFFMKKQQKKQNITQN 126 >3ZTV-A nrPDB Length = 579 Score = 28.1 bits (61), Expect = 8.1, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 7/64 (10%) Query: 320 KFSISGSYVLDQILP-------RLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDE 372 KFS G + + +P +L + KWA+L+G +++ L+ KS +LD + Sbjct: 277 KFSPEGIASITRKIPHVLMSSHKLQVKNSEGKWAELTGDERKKALDTLKSMKSISLDDHD 336 Query: 373 AGTE 376 A T+ Sbjct: 337 AKTD 340 >4C0S-A nrPDB Length = 463 Score = 28.1 bits (61), Expect = 8.3, Method: Compositional matrix adjust. Identities = 13/50 (26%), Positives = 27/50 (54%) Query: 71 PGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120 PG + F+P++I+ + + + S + + +GFN+ +S D+ RG Sbjct: 274 PGMVVTFAPVNITTEVKSVEMHHEALSEALPGDNVGFNVKNVSVKDIRRG 323 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6EE5-A nrPDB 524 e-149 6F02-A nrPDB 495 e-140 3NE4-A nrPDB 487 e-138 1YXA-A nrPDB 463 e-131 6HGE-B nrPDB 456 e-129 2OL2-A nrPDB 444 e-125 6F4U-A nrPDB 437 e-123 5HGC-A nrPDB 436 e-123 2VDY-A nrPDB 432 e-121 1BY7-A nrPDB 407 e-114 3DY0-A nrPDB 405 e-113 4Y40-A nrPDB 400 e-112 4EB1-I nrPDB 392 e-109 1QMB-A nrPDB 387 e-108 1ATT-A nrPDB 383 e-107 4GA7-A nrPDB 382 e-106 1C5G-A nrPDB 382 e-106 2XN5-A nrPDB 381 e-106 3NDA-A nrPDB 380 e-106 2V95-A nrPDB 380 e-106 4ZK0-A nrPDB 378 e-105 1JMJ-A nrPDB 373 e-104 4AJT-A nrPDB 373 e-103 2H4Q-A nrPDB 365 e-101 4KDS-A nrPDB 364 e-101 3LW2-A nrPDB 363 e-101 1HLE-A nrPDB 361 e-100 1UHG-A nrPDB 361 e-100 2H4P-A nrPDB 360 e-100 4DTE-A nrPDB 353 7e-98 5NCS-A nrPDB 350 7e-97 5INW-A nrPDB 350 7e-97 4DY0-A nrPDB 348 4e-96 4P0F-A nrPDB 342 2e-94 3F02-A nrPDB 336 1e-92 1IMV-A nrPDB 335 2e-92 4AJU-A nrPDB 335 2e-92 3ZHA-A nrPDB 323 8e-89 2R9Y-A nrPDB 323 8e-89 1XQJ-A nrPDB 321 3e-88 5NCU-A nrPDB 313 1e-85 3LE2-A nrPDB 304 4e-83 2PEF-A nrPDB 303 1e-82 1K9O-I nrPDB 300 6e-82 6CJ7-A nrPDB 299 1e-81 3OZQ-A nrPDB 294 7e-80 1SEK-A nrPDB 292 2e-79 3PZF-A nrPDB 287 6e-78 2OAY-A nrPDB 286 9e-78 3STO-A nrPDB 279 1e-75 1C8O-A nrPDB 276 1e-74 1SNG-A nrPDB 271 5e-73 1JJO-C nrPDB 264 5e-71 2WXX-A nrPDB 255 3e-68 2WXZ-C nrPDB 253 9e-68 5C98-A nrPDB 249 1e-66 5M3Y-A nrPDB 238 4e-63 1MTP-A nrPDB 235 3e-62 6BJ5-B nrPDB 231 5e-61 1M93-B nrPDB 231 7e-61 Sequences not found previously or not previously below threshold: 4R9I-A nrPDB 86 3e-17 3HSI-A nrPDB 36 0.042 4P2L-A nrPDB 32 0.43 1F2V-A nrPDB 31 1.1 4NOV-A nrPDB 31 1.1 3T59-A nrPDB 30 1.5 5NSQ-A nrPDB 30 1.9 6IRX-A nrPDB 30 3.1 3LLI-A nrPDB 30 3.2 2PFD-A nrPDB 29 4.0 3PPS-A nrPDB 29 4.1 1VCN-A nrPDB 29 4.2 4OVR-A nrPDB 29 4.3 1RKT-A nrPDB 29 5.0 4K8L-A nrPDB 29 5.2 4HW8-A nrPDB 28 8.5 >6EE5-A nrPDB Length = 379 Score = 524 bits (1351), Expect = e-149, Method: Composition-based stats. Identities = 188/380 (49%), Positives = 253/380 (66%), Gaps = 15/380 (3%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 104 + S K+A AN DFAF Y +A +P KNIFFSP+SIS+A AMLSLGA + +QILEG Sbjct: 15 AASSHKLAEANTDFAFSLYRELAKSSPDKNIFFSPVSISSALAMLSLGAKGDTHTQILEG 74 Query: 105 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 LGFN SE+D+H+GFQHLL TLN P GL+ + + LF+ +LK L FL D+ +Y+ Sbjct: 75 LGFN----SEADIHQGFQHLLQTLNRP-KGLQLKTANGLFVDKSLKLLDSFLEDSKKLYQ 129 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 224 A+ F +F D + IND V+K+T GKI DL+ +L D ++VLVN IYFK W+KPF Sbjct: 130 AEAFSVDF-DPEEAKKQINDWVEKQTNGKIKDLLKDLDSDTVLVLVNAIYFKGKWKKPFD 188 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 284 T +DF+VDE TTV+VPMM Q + ++Y HD L C VL + YKG+A++ ILP++G Sbjct: 189 PENTKEEDFHVDEKTTVKVPMMSQKGKFYYY-HDDELSCKVLELPYKGNASMLIILPDEG 247 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 ++ +E+ LTPE L +W L +R+ +EL+LPKF I G+Y L ++L LG TDLFS Sbjct: 248 GLQHLEQSLTPETLSKWLKSLTRRS----VELYLPKFKIEGTYDLKEVLSNLGITDLFSP 303 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404 ADLSGIT+++ L SK+ HKA L+V+E GTEAAAAT S + +RPFL Sbjct: 304 GADLSGITEEK-LYVSKAVHKAVLEVNEEGTEAAAATFLEAIPMSIPPE---FKADRPFL 359 Query: 405 VVIFSTSTQSVLFLGKVVDP 424 +I T S+LF+GKVV+P Sbjct: 360 FLIRENKTGSILFMGKVVNP 379 >6F02-A nrPDB Length = 389 Score = 495 bits (1275), Expect = e-140, Method: Composition-based stats. Identities = 383/383 (100%), Positives = 383/383 (100%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 104 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG Sbjct: 1 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 60 Query: 105 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE Sbjct: 61 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 120 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 224 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI Sbjct: 121 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 180 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 284 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG Sbjct: 181 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 240 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK Sbjct: 241 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 300 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL Sbjct: 301 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 360 Query: 405 VVIFSTSTQSVLFLGKVVDPTKP 427 VVIFSTSTQSVLFLGKVVDPTKP Sbjct: 361 VVIFSTSTQSVLFLGKVVDPTKP 383 >3NE4-A nrPDB Length = 424 Score = 487 bits (1255), Expect = e-138, Method: Composition-based stats. Identities = 183/426 (42%), Positives = 263/426 (61%), Gaps = 16/426 (3%) Query: 4 IDYLLLLLVGLLALSHGQLHVEHDGESC--SNSSHQQILETGEGSPS-LKIAPANADFAF 60 + + +LLL GL L L + G++ +++SH + P+ KI P A+FAF Sbjct: 11 VSWGILLLAGLCCLVPVSLAEDPQGDAAQKTDTSHHD-----QDHPTFNKITPNLAEFAF 65 Query: 61 RFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRG 120 Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNLTE+ E+ +H G Sbjct: 66 SLYRQLAHQSNSTNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNLTEIPEAQIHEG 125 Query: 121 FQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQ 180 FQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F NF DT + Sbjct: 126 FQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFTVNFGDTEEAKK 185 Query: 181 LINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240 IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T +DF+VD+ TT Sbjct: 186 QINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTEEEDFHVDQVTT 245 Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMR 300 V+VPMM + + H + L VL M Y G+AT F LP++GK++ +E LT +++ + Sbjct: 246 VKVPMMKRLGMFNIQ-HCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHLENELTHDIITK 304 Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEAS 360 + +R+ LHLPK SI+G+Y L +L +LG T +FS ADLSG+T++ L+ S Sbjct: 305 FLENEDRRSA----SLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLSGVTEEAPLKLS 360 Query: 361 KSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGK 420 K+ HKA L +DE GTEAA A S ++FN+PF+ ++ +T+S LF+GK Sbjct: 361 KAVHKAVLTIDEKGTEAAGAMFLEAIPMSIPPE---VKFNKPFVFLMIEQNTKSPLFMGK 417 Query: 421 VVDPTK 426 VV+PT+ Sbjct: 418 VVNPTQ 423 >1YXA-A nrPDB Length = 398 Score = 463 bits (1191), Expect = e-131, Method: Composition-based stats. Identities = 179/400 (44%), Positives = 242/400 (60%), Gaps = 3/400 (0%) Query: 26 HDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAA 85 DG +++ Q+ + G SL +A N DFAF Y + + P NI FSPLSISAA Sbjct: 2 PDGTLGMDAAVQEDHDNGTQLDSLTLASINTDFAFSLYKELVLKNPDTNIVFSPLSISAA 61 Query: 86 YAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFL 145 A++SLGA ++ +ILEGL FNLTE SE+D+H+GF HLL LN P ++ GSALF+ Sbjct: 62 LALVSLGAKGNTLEEILEGLKFNLTETSEADIHQGFGHLLQRLNQPKDQVQISTGSALFI 121 Query: 146 SHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDV 205 + L +F +Y+A+ F +F +LIND+V+K+T+G I +LVS+L K Sbjct: 122 EKRQQILTEFQEKAKTLYQAEAFTADFQQPRQAKKLINDYVRKQTQGMIKELVSDLDKRT 181 Query: 206 LMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSV 265 LMVLVNYIYFKA W+ PF T +FY + V VPMM + Y D L C+V Sbjct: 182 LMVLVNYIYFKAKWKVPFDPLDTFKSEFYCGKRRPVIVPMMSMEDLTTPYFRDEELSCTV 241 Query: 266 LRMDYKGDATVFFILPNQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISG 325 + + Y G+A+ FILP+QG+M+++E L PE L +W N L+ R ELHLPKFSIS Sbjct: 242 VELKYTGNASALFILPDQGRMQQVEASLQPETLRKWKNSLKPRMID---ELHLPKFSIST 298 Query: 326 SYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAI 385 Y L+ +L +LG ++FS ADLS IT + L S+ HKA LDV E GTEAAAAT Sbjct: 299 DYSLEDVLSKLGIREVFSTQADLSAITGTKDLRVSQVVHKAVLDVAETGTEAAAATGVKF 358 Query: 386 KFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPT 425 SA+ + FNRPFL++IF T T+ F+ K+ +P Sbjct: 359 VPMSAKLYPLTVYFNRPFLIMIFDTETEIAPFIAKIANPK 398 >6HGE-B nrPDB Length = 409 Score = 456 bits (1173), Expect = e-129, Method: Composition-based stats. Identities = 176/377 (46%), Positives = 236/377 (62%), Gaps = 4/377 (1%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +A AN DFAF Y + + P KN+ FSPLSIS A A LSLGA + + ++IL+GL FNLT Sbjct: 35 LASANVDFAFSLYKQLVLKAPDKNVIFSPLSISTALAFLSLGAHNTTLTEILKGLKFNLT 94 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E SE+++H+ FQHLL TLN L+ +G+A+F+ L L +F D +Y ++ F T Sbjct: 95 ETSEAEIHQSFQHLLRTLNQSSDELQLSMGNAMFVKEQLSLLDRFTEDAKRLYGSEAFAT 154 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 +F D+ +LIND+VK TRGKI DL+ +L +MVLVNYI+FKA WE PF T Sbjct: 155 DFQDSAAAKKLINDYVKNGTRGKITDLIKDLDSQTMMVLVNYIFFKAKWEMPFDPQDTHQ 214 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290 FY+ + V VPMM Y D L C+V++++Y G+A+ FILP+Q KM E+E Sbjct: 215 SRFYLSKKKWVMVPMMSLHHLTIPYFRDEELSCTVVQLNYTGNASALFILPDQDKMEEVE 274 Query: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350 +L+ E L RW + L R EL+LPKFSIS Y L+ IL +LG + F+ ADLSG Sbjct: 275 AMLSRETLNRWGDSLEFREIG---ELYLPKFSISRDYNLNDILLQLGIEEAFTSKADLSG 331 Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTN-RHILRFNRPFLVVIFS 409 IT + L S+ HKA LDV E GTEA+AAT+ I SA R I+RFNRPFL++I Sbjct: 332 ITGARNLAVSQVVHKAVLDVFEEGTEASAATAVKITLLSALVETRTIVRFNRPFLMIIVD 391 Query: 410 TSTQSVLFLGKVVDPTK 426 T S+ F+ KV +P + Sbjct: 392 HFTWSIFFMSKVTNPKQ 408 >2OL2-A nrPDB Length = 395 Score = 444 bits (1143), Expect = e-125, Method: Composition-based stats. Identities = 176/368 (47%), Positives = 244/368 (66%), Gaps = 8/368 (2%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 DF F Y +AS P +NIFFSP+SIS + AMLSLGA S ++ QILEGLG NL + SE + Sbjct: 36 DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 95 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTV 176 +HRGFQ LL LN P G + +G+ALF + F++ +Y A F TNF D+ Sbjct: 96 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 155 Query: 177 GTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVD 236 G ++ IND+V K+T+GKIVDL+ L + ++++VNYI+FKA WE F T +DFYV Sbjct: 156 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 215 Query: 237 ENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPE 296 T VRVPMM ++ ++H YL DR L C V+ + Y+G+AT FILP++GKM+++E L+ + Sbjct: 216 SETVVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEK 274 Query: 297 MLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQK 356 L +W + +KR +LEL+LPKFSI GSY L+++LP LG +++F+ ADLSGI+ Sbjct: 275 TLRKWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSN 330 Query: 357 LEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVL 416 ++ S+ HKA ++VDE+GT AAAAT F SA+ N L FNRPFL+ I ++L Sbjct: 331 IQVSEMVHKAVVEVDESGTRAAAATGTIFTFRSARLNSQRLVFNRPFLMFIVDN---NIL 387 Query: 417 FLGKVVDP 424 FLGKV P Sbjct: 388 FLGKVNRP 395 >6F4U-A nrPDB Length = 341 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 340/340 (100%), Positives = 340/340 (100%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 107 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF Sbjct: 2 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 61 Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL Sbjct: 62 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 121 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 227 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR Sbjct: 122 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 181 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 287 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR Sbjct: 182 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMR 241 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 347 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD Sbjct: 242 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 301 Query: 348 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 387 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF Sbjct: 302 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 341 >5HGC-A nrPDB Length = 380 Score = 436 bits (1122), Expect = e-123, Method: Composition-based stats. Identities = 175/384 (45%), Positives = 254/384 (66%), Gaps = 8/384 (2%) Query: 42 TGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQI 101 E +LK+ P NADFAF+F+ + E P KNIF+SP+SIS A+AML+LGA S ++SQI Sbjct: 2 NAEAMAALKLVPNNADFAFQFFREVTQEAPNKNIFYSPVSISTAFAMLALGARSATQSQI 61 Query: 102 LEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMA 161 LEGL FNLTE+ E ++H GF +L+H LN P G++ + +A+F++ L L KFL+D A Sbjct: 62 LEGLAFNLTEIQEKEIHEGFHNLIHMLNHPEGGVQLNMMNAIFVTAALALLRKFLDDAKA 121 Query: 162 VYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEK 221 +Y+ + F T+F + IND+++++T GKI +LV ++ +M+L +++YFK WEK Sbjct: 122 LYQLEAFTTDFNKPTEAEKQINDYIERKTHGKITNLVKDMDPQTVMLLASFVYFKGSWEK 181 Query: 222 PFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILP 281 PF + T ++F+VD TTV+VPMM Q +Y D L C+V+R+ Y G AT F +LP Sbjct: 182 PFEAEHTEEREFFVDAETTVKVPMMYQMGRFDFYF-DEELSCTVVRLHYNGSATAFLVLP 240 Query: 282 NQGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDL 341 +GKM+++E+ L E + +W++ L F + + L+ PKFSISGSY + L ++G D+ Sbjct: 241 AKGKMKQLEQTLDKETIQKWSDHL----FQRFMNLYFPKFSISGSYEISNTLRKMGIVDV 296 Query: 342 FSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNR 401 F+ ADLSGIT L+ SK HKA+LDVDE GTEAAAAT+ I S + F+ Sbjct: 297 FTNQADLSGITGSPDLKVSKVVHKASLDVDEKGTEAAAATAVEIMPISFPP---TIEFSH 353 Query: 402 PFLVVIFSTSTQSVLFLGKVVDPT 425 PFL++IF T S LF+GK+V+PT Sbjct: 354 PFLMLIFDRDTNSTLFIGKIVNPT 377 >2VDY-A nrPDB Length = 373 Score = 432 bits (1111), Expect = e-121, Method: Composition-based stats. Identities = 172/374 (45%), Positives = 239/374 (63%), Gaps = 8/374 (2%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +A AN DFAF Y + + +P KNIF SP+SIS A AMLSLG C H+R+Q+L+GLGFNLT Sbjct: 7 LASANVDFAFSLYKHLVALSPKKNIFISPVSISMALAMLSLGTCGHTRAQLLQGLGFNLT 66 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E SE+++H+GFQHL LE +G+ALFL +L+ L F D YE+++ Sbjct: 67 ERSETEIHQGFQHLHQLFAKSDTSLEMTMGNALFLDGSLELLESFSADIKHYYESEVLAM 126 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 NF D + IN +VK +T+GKIVDL S L ++VLVNYI+FK W +PF + T Sbjct: 127 NFQDWATASRQINSYVKNKTQGKIVDLFSGLDSPAILVLVNYIFFKGTWTQPFDLASTRE 186 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290 ++FYVDE T V+VPMMLQ YLHD LPC +++M+Y G+ TVFFILP++GKM + Sbjct: 187 ENFYVDETTVVKVPMMLQSSTIS-YLHDSELPCQLVQMNYVGNGTVFFILPDKGKMNTVI 245 Query: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350 L+ + + RW+ L +++L++PK +ISG Y L +L +G DLF+ A+ S Sbjct: 246 AALSRDTINRWSAGLTSS----QVDLYIPKVTISGVYDLGDVLEEMGIADLFTTQANFSR 301 Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFST 410 IT+ +L++SK HKA L ++E GTEAA A S ILRFN+PF+++IF Sbjct: 302 ITQDAQLKSSKVVHKAVLQLNEEGTEAAGAMFLEAIPRS---KPIILRFNQPFIIMIFDH 358 Query: 411 STQSVLFLGKVVDP 424 T S LFL +V++P Sbjct: 359 FTWSSLFLARVMNP 372 >1BY7-A nrPDB Length = 382 Score = 407 bits (1047), Expect = e-114, Method: Composition-based stats. Identities = 108/386 (27%), Positives = 187/386 (48%), Gaps = 15/386 (3%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 + AN FA + +A +P +N+F SP SIS+ AM+ +G+ + Q+ + L FN Sbjct: 2 EDLCVANTLFALNLFKHLAKASPTQNLFLSPWSISSTMAMVYMGSRGSTEDQMAKVLQFN 61 Query: 109 LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLF 168 + +H F+ L +N + LF + F +++ Y ++ Sbjct: 62 EVGAAADKIHSSFRSLSSAINASTGNYLLESVNKLFGEKSASFREEYIRLCQKYYSSEPQ 121 Query: 169 HTNFYD-TVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFIS 225 +F + + IN VK +T+GKI +L+ E + D MVLVN +YFK W+ PF Sbjct: 122 AVDFLECAEEARKKINSWVKTQTKGKIPNLLPEGSVDGDTRMVLVNAVYFKGKWKTPFEK 181 Query: 226 SRTTPKDFYVDENTTVRVPMML-QDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ- 283 F V+ V MM +++ + Y+ D L +L + Y GD ++F +LP++ Sbjct: 182 KLNGLYPFRVNSAQRTPVQMMYLREKLNIGYIED--LKAQILELPYAGDVSMFLLLPDEI 239 Query: 284 ----GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFT 339 + +E +T + L +W + + + ++E+++P+F + Y L IL +G Sbjct: 240 ADVSTGLELLESEITYDKLNKWTS--KDKMAEDEVEVYIPQFKLEEHYELRSILRSMGME 297 Query: 340 DLFSKW-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILR 398 D F+K A+ SG++++ L S+ FH+A +DV+E GTEAAA T + + Sbjct: 298 DAFNKGRANFSGMSERNDLFLSEVFHQAMVDVNEEGTEAAAGTGGVMTGRTGHGGPQ-FV 356 Query: 399 FNRPFLVVIFSTSTQSVLFLGKVVDP 424 + PFL +I T +LF G+ P Sbjct: 357 ADHPFLFLIMHKITNCILFFGRFSSP 382 >3DY0-A nrPDB Length = 336 Score = 405 bits (1042), Expect = e-113, Method: Composition-based stats. Identities = 158/331 (47%), Positives = 222/331 (67%), Gaps = 5/331 (1%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 DF F Y +AS P +NIFFSP+SIS + AMLSLGA S ++ QILEGLG NL + SE + Sbjct: 11 DFTFDLYRALASAAPSQNIFFSPVSISMSLAMLSLGAGSSTKMQILEGLGLNLQKSSEKE 70 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTV 176 +HRGFQ LL LN P G + +G+ALF + F++ +Y A F TNF D+ Sbjct: 71 LHRGFQQLLQELNQPRDGFQLSLGNALFTDLVVDLQDTFVSAMKTLYLADTFPTNFRDSA 130 Query: 177 GTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVD 236 G ++ IND+V K+T+GKIVDL+ L + ++++VNYI+FKA WE F T +DFYV Sbjct: 131 GAMKQINDYVAKQTKGKIVDLLKNLDSNAVVIMVNYIFFKAKWETSFNHKGTQEQDFYVT 190 Query: 237 ENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVLTPE 296 T VRVPMM ++ ++H YL DR L C V+ + Y+G+AT FILP++GKM+++E L+ + Sbjct: 191 SETVVRVPMMSREDQYH-YLLDRNLSCRVVGVPYQGNATALFILPSEGKMQQVENGLSEK 249 Query: 297 MLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQK 356 L +W + +KR +LEL+LPKFSI GSY L+++LP LG +++F+ ADLSGI+ Sbjct: 250 TLRKWLKMFKKR----QLELYLPKFSIEGSYQLEKVLPSLGISNVFTSHADLSGISNHSN 305 Query: 357 LEASKSFHKATLDVDEAGTEAAAATSFAIKF 387 ++ S+ HKA ++VDE+GT AAAAT F Sbjct: 306 IQVSEMVHKAVVEVDESGTRAAAATGTIFTF 336 >4Y40-A nrPDB Length = 414 Score = 400 bits (1027), Expect = e-112, Method: Composition-based stats. Identities = 127/381 (33%), Positives = 217/381 (56%), Gaps = 10/381 (2%) Query: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILE 103 + + ++A N D F+ +A PG+NIF SPLSIS A++ML LGA + +I + Sbjct: 41 QRMAAKELARQNMDLGFKLLKKLAFYNPGRNIFLSPLSISTAFSMLCLGAQDSTLDEIKQ 100 Query: 104 GLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVY 163 GFN ++ E D+H GF +++H L L+ +G+ LF+ L+ KFL D Y Sbjct: 101 --GFNFRKMPEKDLHEGFHYIIHELTQKTQDLKLSIGNTLFIDQRLQPQRKFLEDAKNFY 158 Query: 164 EAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPF 223 A+ TNF + + IND + ++T GKI +L+ + +M+L NYI+F+A W+ F Sbjct: 159 SAETILTNFQNLEMAQKQINDFISQKTHGKINNLIENIDPGTVMLLANYIFFRARWKHEF 218 Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ 283 + T +DF++++N++V+VPMM + + D L C++L + Y+ + T FILP++ Sbjct: 219 DPNVTKEEDFFLEKNSSVKVPMMFRSGIYQVGY-DDKLSCTILEIPYQKNITAIFILPDE 277 Query: 284 GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 GK++ +E+ L + RW LL +R + + +P+ ++G++ L + L +G + +F Sbjct: 278 GKLKHLEKGLQVDTFSRWKTLLSRR----VVCVSVPRLHMTGTFDLKKTLSYIGVSKIFE 333 Query: 344 KWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPF 403 + DL+ I + L+ ++ HKA L +DE GTE AA T ++ ++P+ Sbjct: 334 EHGDLTKIAPHRSLKVGEAVHKAELKMDERGTEGAAGTGAQTLPM---ETPLCVKIDKPY 390 Query: 404 LVVIFSTSTQSVLFLGKVVDP 424 L++I+S SVLFLGK+V+P Sbjct: 391 LLLIYSEKIPSVLFLGKIVNP 411 >4EB1-I nrPDB Length = 440 Score = 392 bits (1008), Expect = e-109, Method: Composition-based stats. Identities = 129/427 (30%), Positives = 210/427 (49%), Gaps = 25/427 (5%) Query: 17 LSHGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIA-SETPGKNI 75 ++ ++ + ++ + +Q + +++ AN+ FA FY +A S+ NI Sbjct: 17 MNPMCIYRSPEKKATEDEGSEQKIPEATNRRVWELSKANSRFATTFYQHLADSKNDNDNI 76 Query: 76 FFSPLSISAAYAMLSLGACSHSRSQILEGLGFN-LTELSESDVHRGFQHLLHTLNLP-GH 133 F SPLSIS A+AM LGAC+ + Q++E F+ ++E + +H F L L Sbjct: 77 FLSPLSISTAFAMTKLGACNDTLQQLMEVFKFDTISEKTSDQIHFFFAKLNCRLYRKANK 136 Query: 134 GLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY-DTVGTIQLINDHVKKETRG 192 + + LF +L F + + + VY AKL +F + + IN V +T G Sbjct: 137 ASKLVSANRLFGDKSLTFNETYQDISELVYGAKLQPLDFKENAEQSRAAINKWVSNKTEG 196 Query: 193 KIVDLVSELKKD----------VLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVR 242 +I D++ + ++VLVN IYFK LW+ F T + FY + + Sbjct: 197 RITDVIPSEAINVLVLVNTRTSTVLVLVNTIYFKGLWKSKFSPENTRKELFYKADGESCS 256 Query: 243 VPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATVFFILPNQGK-MREIEEVLTPEMLMR 300 MM Q+ + + VL + +KGD T+ ILP K + ++E+ LTPE+L Sbjct: 257 ASMMYQEGKFRY--RRVAEGTQVLELPFKGDDITMVLILPKPEKSLAKVEKELTPEVLQE 314 Query: 301 WNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS-KWADLSGIT--KQQKL 357 W + L + +H+P+F I + L + L +G DLFS + + L GI + L Sbjct: 315 WLDELEEMMLV----VHMPRFRIEDGFSLKEQLQDMGLVDLFSPEKSKLPGIVAEGRDDL 370 Query: 358 EASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLF 417 S +FHKA L+V+E G+EAAA+T+ I S NR + NRPFLV I +++F Sbjct: 371 YVSDAFHKAFLEVNEEGSEAAASTAVVIAGRSLNPNRVTFKANRPFLVFIREVPLNTIIF 430 Query: 418 LGKVVDP 424 +G+V +P Sbjct: 431 MGRVANP 437 >1QMB-A nrPDB Length = 326 Score = 387 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 157/332 (47%), Positives = 214/332 (64%), Gaps = 7/332 (2%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 KI P A+FAF Y +A ++ NIFFSP+SI+ A+AMLSLG + + +ILEGL FNL Sbjct: 1 KITPNLAEFAFSLYRQLAHQS-STNIFFSPVSIATAFAMLSLGTKADTHDEILEGLNFNL 59 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 TE+ E+ +H GFQ LL TLN P L+ G+ LFLS LK + KFL D +Y ++ F Sbjct: 60 TEIPEAAIHEGFQELLRTLNQPDSQLQLTTGNGLFLSEGLKLVDKFLEDVKKLYHSEAFT 119 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 NF DT + IND+V+K T+GKIVDLV EL +D + LVNYI+FK WE+PF T Sbjct: 120 VNFGDTEEAKKQINDYVEKGTQGKIVDLVKELDRDTVFALVNYIFFKGKWERPFEVKDTE 179 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREI 289 +DF+VD+ TTV+VPMM + + H + L VL M Y G+AT F LP++GK++ + Sbjct: 180 EEDFHVDQVTTVKVPMMKRLGMFNIQ-HCKKLSSWVLLMKYLGNATAIFFLPDEGKLQHL 238 Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLS 349 E LT +++ ++ N + LHLPK SI+G+Y L +L +LG T +FS ADLS Sbjct: 239 ENELTHDIITKFLE-----NDRRSASLHLPKLSITGTYDLKSVLGQLGITKVFSNGADLS 293 Query: 350 GITKQQKLEASKSFHKATLDVDEAGTEAAAAT 381 G+T++ L+ SK+ HKA L +DE GTEAA A Sbjct: 294 GVTEEAPLKLSKAVHKAVLTIDEKGTEAAGAM 325 >1ATT-A nrPDB Length = 429 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 127/386 (32%), Positives = 208/386 (53%), Gaps = 17/386 (4%) Query: 50 KIAPANADFAFRFYYLIA-SETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ AN+ FA FY +A S+ NIF SPLSIS A+AM LGAC+++ +Q++E F+ Sbjct: 47 ELSKANSHFATAFYQHLADSKNNNDNIFLSPLSISTAFAMTKLGACNNTLTQLMEVFKFD 106 Query: 109 -LTELSESDVHRGFQHLLHTLNLP-GHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAK 166 ++E + +H F L L E + LF ++ F + + + VY AK Sbjct: 107 TISEKTSDQIHFFFAKLNCRLYRKANKSSELVSANRLFGDKSITFNETYQDISEVVYGAK 166 Query: 167 LFHTNFY-DTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPF 223 L +F + + IN + +T G+I D++ + + ++VLVN IYFK LW+ F Sbjct: 167 LQPLDFKGNAEQSRLTINQWISNKTEGRITDVIPPQAINEFTVLVLVNTIYFKGLWKSKF 226 Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATVFFILPN 282 T + FY + + V MM Q+ + + VL + +KGD T+ ILP Sbjct: 227 SPENTRKELFYKADGESCSVLMMYQESKFRY--RRVAESTQVLELPFKGDDITMVLILPK 284 Query: 283 -QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDL 341 + + ++E+ LTP+ML W + L + L +H+P+F I S+ + + L +G DL Sbjct: 285 LEKTLAKVEQELTPDMLQEWLDELTE----TLLVVHMPRFRIEDSFSVKEQLQDMGLEDL 340 Query: 342 FS-KWADLSGITKQQ--KLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILR 398 FS + + L GI + L S +FHKA L+V+E G+EAAA+T +I S ++R + Sbjct: 341 FSPEKSRLPGIVAEGRSDLYVSDAFHKAFLEVNEEGSEAAASTVISIAGRSLNSDRVTFK 400 Query: 399 FNRPFLVVIFSTSTQSVLFLGKVVDP 424 NRPFLV+I + +++F+G+V +P Sbjct: 401 ANRPFLVLIREVALNTIIFMGRVANP 426 >4GA7-A nrPDB Length = 389 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 127/386 (32%), Positives = 195/386 (50%), Gaps = 18/386 (4%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ AN FA + ++ P NIF SP SIS+A AM+ LG ++ +Q+ + FN Sbjct: 12 EQLSSANTRFALDLFLALSENNPAGNIFISPFSISSAMAMVFLGTRGNTAAQLSKTFHFN 71 Query: 109 LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLF 168 E +VH FQ L +N G ++ + L+ FL +FL T Y A L Sbjct: 72 TVE----EVHSRFQSLNADINKRGASYILKLANRLYGEKTYNFLPEFLVSTQKTYGADLA 127 Query: 169 HTNFYDTVG-TIQLINDHVKKETRGKIVDLVSELKKD--VLMVLVNYIYFKALWEKPFIS 225 +F + IN VK +T GKI +L++ D +VLVN IYFK W+ F+ Sbjct: 128 SVDFQHASEDARKTINQWVKGQTEGKIPELLASGMVDNMTKLVLVNAIYFKGNWKDKFMK 187 Query: 226 SRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILPNQ- 283 TT F +++ V MM Q ++ + + L C VL + Y+G + ++ +LP+ Sbjct: 188 EATTNAPFRLNKKDRKTVKMMYQKKKFAYGYIED-LKCRVLELPYQGEELSMVILLPDDI 246 Query: 284 ----GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFT 339 +++IEE LT E L W + + ++ + LP+F + SY L+ L RLG Sbjct: 247 EDESTGLKKIEEQLTLEKLHEWTK--PENLDFIEVNVSLPRFKLEESYTLNSDLARLGVQ 304 Query: 340 DLF-SKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILR 398 DLF S ADLSG++ + + SK HK+ ++V+E GTEAAAAT+ F + Sbjct: 305 DLFNSSKADLSGMSGARDIFISKIVHKSFVEVNEEGTEAAAATAGIATFCMDDPEEN-FT 363 Query: 399 FNRPFLVVIFSTSTQSVLFLGKVVDP 424 + PFL I S+ S+LFLG+ P Sbjct: 364 ADHPFLFFIRHNSSGSILFLGRFSSP 389 >1C5G-A nrPDB Length = 402 Score = 382 bits (980), Expect = e-106, Method: Composition-based stats. Identities = 104/387 (26%), Positives = 193/387 (49%), Gaps = 18/387 (4%) Query: 46 SPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGL 105 P +A +DF R + +A + +N+ FSP +++ AML L ++ QI + Sbjct: 26 HPPSYVAHLASDFGVRVFQQVAQASKDRNVVFSPYGVASVLAMLQLTTGGETQQQIQAAM 85 Query: 106 GFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEA 165 GF + + + +HL L P + E A+F+ +LK + F+ ++ + Sbjct: 86 GFKIDDKGMA---PALRHLYKELMGPWNKDEISTTDAIFVQRDLKLVQGFMPHFFRLFRS 142 Query: 166 KLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKD--VLMVLVNYIYFKALWEKPF 223 + +F + +IND VK T+G I +L+ + D +VLVN +YF W+ PF Sbjct: 143 TVKQVDFSEVERARFIINDWVKTHTKGMISNLLGKGAVDQLTRLVLVNALYFNGQWKTPF 202 Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGD-ATVFFIL 280 S T + F+ + +TV VPMM Q + ++ + +L + Y GD ++F Sbjct: 203 PDSSTHRRLFHKSDGSTVSVPMMAQTNKFNYTEFTTPDGHYYDILELPYHGDTLSMFIAA 262 Query: 281 PNQGK--MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGF 338 P + + + + +L+ +++ W + + L LPKFS+ L + L LG Sbjct: 263 PYEKEVPLSALTNILSAQLISHWKGNMTRLPRL----LVLPKFSLETEVDLRKPLENLGM 318 Query: 339 TDLFSK-WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHIL 397 TD+F + AD + ++ Q+ L +++ K ++V+E+GT A+++T+ + SA+ + Sbjct: 319 TDMFRQFQADFTSLSDQEPLHVAQALQKVKIEVNESGTVASSSTAVIV---SARMAPEEI 375 Query: 398 RFNRPFLVVIFSTSTQSVLFLGKVVDP 424 +RPFL V+ T +VLF+G+V++P Sbjct: 376 IMDRPFLFVVRHNPTGTVLFMGQVMEP 402 >2XN5-A nrPDB Length = 350 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 156/343 (45%), Positives = 220/343 (64%), Gaps = 6/343 (1%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 K++ NADFAF Y ETP KNIFFSP+SISAA MLS GAC ++++I+E LGFNL Sbjct: 10 KMSSINADFAFNLYRRFTVETPDKNIFFSPVSISAALVMLSFGACCSTQTEIVETLGFNL 69 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 T+ ++ GFQHL+ +LN P LE ++G+ALF+ +LK LAKFLND +YE ++F Sbjct: 70 TDTPMVEIQHGFQHLICSLNFPKKELELQIGNALFIGKHLKPLAKFLNDVKTLYETEVFS 129 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 T+F + Q IN HV+ +T+GK+V L+ +LK + +MVLVNYI+FKA W PF S+T Sbjct: 130 TDFSNISAAKQEINSHVEMQTKGKVVGLIQDLKPNTIMVLVNYIHFKAQWANPFDPSKTE 189 Query: 230 P-KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMRE 288 F +D+ TTV+VPMM Q E +++L D L C+VL+MDY +A F+LP +G+M Sbjct: 190 DSSSFLIDKTTTVQVPMMHQ-MEQYYHLVDMELNCTVLQMDYSKNALALFVLPKEGQMES 248 Query: 289 IEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADL 348 +E ++ + L +WN LL+K ++L +PKFSIS +Y L L ++G +S+ AD Sbjct: 249 VEAAMSSKTLKKWNRLLQK----GWVDLFVPKFSISATYDLGATLLKMGIQHAYSENADF 304 Query: 349 SGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQ 391 SG+T+ L+ S + HKA L + E GTEAA A S Sbjct: 305 SGLTEDNGLKLSNAAHKAVLHIGEKGTEAAGAMFLEAIPRSIP 347 >3NDA-A nrPDB Length = 377 Score = 380 bits (977), Expect = e-106, Method: Composition-based stats. Identities = 116/377 (30%), Positives = 181/377 (48%), Gaps = 11/377 (2%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 K+ AN F R + S P KN+FFSP S+S A M GA ++ ++ +GLGF+ Sbjct: 6 KLTKANNRFGLRLLRALPS-GPEKNVFFSPYSVSTAMGMAFAGARGQTQQELSQGLGFSD 64 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 +L+++ V + H L V +A + L L + + + + A+L Sbjct: 65 VDLTDAGVLDAYTHHTERLKSTPSNSTLDVANAAAIQRTLALLNSYESALQSSFGAELHK 124 Query: 170 TNF-YDTVGTIQLINDHVKKETRGKIVDLVSE-LKKDVLMVLVNYIYFKALWEKPFISSR 227 +F + + +N+ VK++T KI L +E L D L+VL+N IYFK W F+ Sbjct: 125 VDFAGEPQAAVDFVNNWVKRKTHDKIEKLFNEPLDPDTLLVLLNAIYFKGEWNTAFVKEH 184 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILPNQ-GK 285 T + F+ T V V M + + D L V+ + Y+G D T+ +LP + Sbjct: 185 TEKRQFFNGGVTPVEVDTMRLEARIKYRFFDD-LQVEVVELPYRGLDYTMAILLPKENTG 243 Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 + +++ LT + + + LR+R K+ + LPKF + Y L L LG +F Sbjct: 244 VEGLKQNLTIDRFQNYLSDLRER----KITVLLPKFKLETKYSLKAPLQSLGIKQIFESG 299 Query: 346 ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLV 405 ADLSGI L S HKA ++V+E GT AAA T I +S + R + PFL Sbjct: 300 ADLSGI-NDGSLRVSAVEHKAVVEVNEEGTVAAATTGVVIVPYSLGPEPVVFRVDHPFLF 358 Query: 406 VIFSTSTQSVLFLGKVV 422 I +T T + F+G+V Sbjct: 359 FIRNTRTDDIFFVGQVN 375 >2V95-A nrPDB Length = 371 Score = 380 bits (976), Expect = e-106, Method: Composition-based stats. Identities = 146/374 (39%), Positives = 215/374 (57%), Gaps = 12/374 (3%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +AP N DFAF Y + + P KN SP+SIS A AM+SLG+ ++Q L+ LGFNLT Sbjct: 9 LAPTNVDFAFNLYQRLVALNPDKNTLISPVSISMALAMVSLGSA---QTQSLQSLGFNLT 65 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E SE+++H+ FQ+L + L GLE +G+A+FL LK FL D YE++ Sbjct: 66 ETSEAEIHQSFQYLNYLLKQSDTGLEMNMGNAMFLLQKLKLKDSFLADVKQYYESEALAI 125 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 +F D Q IN HVK +T+GKI + S+L +LVNYI+ + +WE PF T Sbjct: 126 DFEDWTKASQQINQHVKDKTQGKIEHVFSDLDSPASFILVNYIFLRGIWELPFSPENTRE 185 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIE 290 +DFYV+E +TV+VPMM+Q Y D PC +++MDY G+ T FFILP+QG+M + Sbjct: 186 EDFYVNETSTVKVPMMVQSGSI-GYFRDSVFPCQLIQMDYVGNGTAFFILPDQGQMDTVI 244 Query: 291 EVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSG 350 L+ + + RW L+ R ++ L++PKFS+S +Y L +L L DL + +D SG Sbjct: 245 AALSRDTIDRWGKLMTPR----QVNLYIPKFSMSDTYDLKDVLEDLNIKDLLTNQSDFSG 300 Query: 351 ITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFST 410 TK L + HKA L +DE + + S + ++FN+PF++++F Sbjct: 301 NTKDVPLTLT-MVHKAMLQLDEGNVLPNSTNGAPLHLRSEPLD---IKFNKPFILLLFDK 356 Query: 411 STQSVLFLGKVVDP 424 T S L + +VV+P Sbjct: 357 FTWSSLMMSQVVNP 370 >4ZK0-A nrPDB Length = 390 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 126/393 (32%), Positives = 191/393 (48%), Gaps = 21/393 (5%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 ++ AN F F + + NIF+SP+SI++A M+ LGA ++ QI + L F+ Sbjct: 2 NSLSEANTKFMFDLFQQFRK-SKENNIFYSPISITSALGMVLLGAKDNTAQQIKKVLHFD 60 Query: 109 L------------TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFL 156 +VH FQ LL N E ++ + LF FL ++L Sbjct: 61 QVTENTTGKAATYHVDRSGNVHHQFQKLLTEFNKSTDAYELKIANKLFGEKTYLFLQEYL 120 Query: 157 NDTMAVYEAKLFHTNFYD-TVGTIQLINDHVKKETRGKIVDLVSELK--KDVLMVLVNYI 213 + Y+ + +F + + + IN V+ +T KI +L+ E + +VLVN I Sbjct: 121 DAIKKFYQTSVESVDFANAPEESRKKINSWVESQTNEKIKNLIPEGNIGSNTTLVLVNAI 180 Query: 214 YFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG- 272 YFK WEK F T + F+ ++NT + MM Q H + + VL + YKG Sbjct: 181 YFKGQWEKKFNKEDTKEEKFWPNKNTYKSIQMMRQYTSFH-FASLEDVQAKVLEIPYKGK 239 Query: 273 DATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQ 331 D ++ +LPN+ ++++EE LT E LM W +L R +++LHLP+F + SY L Sbjct: 240 DLSMIVLLPNEIDGLQKLEEKLTAEKLMEWTSLQNMR--ETRVDLHLPRFKVEESYDLKD 297 Query: 332 ILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQ 391 L +G D+F+ ADLSG+T + L S HKA ++V E G EAAAAT+ S Sbjct: 298 TLRTMGMVDIFNGDADLSGMTGSRGLVLSGVLHKAFVEVTEEGAEAAAATAVVGFGSSPT 357 Query: 392 TNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 + N PFL I T S+LF G+ P Sbjct: 358 STNEEFHCNHPFLFFIRQNKTNSILFYGRFSSP 390 >1JMJ-A nrPDB Length = 480 Score = 373 bits (959), Expect = e-104, Method: Composition-based stats. Identities = 114/403 (28%), Positives = 192/403 (47%), Gaps = 18/403 (4%) Query: 32 SNSSHQQILETGEGSPS-LKIAPANADFAFRFYYLIASETPG-KNIFFSPLSISAAYAML 89 S+ S IL+ G ++ NA FAF Y ++ + NIF +P+ IS A M+ Sbjct: 87 SDVSAGNILQLFHGKSRIQRLNILNAKFAFNLYRVLKDQVNTFDNIFIAPVGISTAMGMI 146 Query: 90 SLGACSHSRSQILEGLGFNL-----TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALF 144 SLG + Q+ L F ++ + +H F+ L H L G R + L+ Sbjct: 147 SLGLKGETHEQVHSILHFKDFVNASSKYEITTIHNLFRKLTHRLFRRNFGYTLRSVNDLY 206 Query: 145 LSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKD 204 + L F Y A+ +F D I N+H+ K T+G I D + + Sbjct: 207 IQKQFPILLDFKTKVREYYFAEAQIADFSDPA-FISKTNNHIMKLTKGLIKDALENIDPA 265 Query: 205 VLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCS 264 M+++N IYFK W F T +F ++E V+V MM Q + + +D+ L C Sbjct: 266 TQMMILNCIYFKGSWVNKFPVEMTHNHNFRLNEREVVKVSMM-QTKGNFLAANDQELDCD 324 Query: 265 VLRMDYKGDATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSI 323 +L+++Y G ++ ++P++ M+ +E LTP ++ RW + R E+ LPKF + Sbjct: 325 ILQLEYVGGISMLIVVPHKMSGMKTLEAQLTPRVVERWQKSMTNRT----REVLLPKFKL 380 Query: 324 SGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSF 383 +Y L + L +G LF K +++GI+ Q++ H+ T+ V+E GT+A T+ Sbjct: 381 EKNYNLVESLKLMGIRMLFDKNGNMAGIS-DQRIAIDLFKHQGTITVNEEGTQATTVTTV 439 Query: 384 AIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTK 426 S Q +RPFL +I+ T +LF+G+V +P++ Sbjct: 440 GFMPLSTQ---VRFTVDRPFLFLIYEHRTSCLLFMGRVANPSR 479 >4AJT-A nrPDB Length = 427 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 107/381 (28%), Positives = 186/381 (48%), Gaps = 11/381 (2%) Query: 47 PSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLG 106 S +++ + F F I+ G N+ FSP +S A L LG ++ QI GL Sbjct: 54 ASQQLSNETSSFGFNLLRKISMRHDG-NVIFSPFGLSVAMVNLMLGTKGETKVQIENGLN 112 Query: 107 FNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAK 166 + + + L GS F+ + + N + ++ + Sbjct: 113 LQALSQAGPLILPALFKKVKETFSSNRDLGLSQGSFAFIHKDFDIKETYFNLSKKYFDIE 172 Query: 167 LFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISS 226 NF ++ LIN + KET GKI L E+ + ++LV+Y+ FK W PF S Sbjct: 173 YVSINFQNSSQARGLINHCIVKETEGKIPKLFDEINPETKLILVDYVLFKGKWLTPFDPS 232 Query: 227 RTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GK 285 T F++D+ ++VPMM ++ D+ C +L++ Y+G+AT+ +L + G Sbjct: 233 FTEADTFHLDKYRAIKVPMMYREGNFT-STFDKKFRCHILKLPYQGNATMLVVLMEKTGD 291 Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKW 345 +E+ LT +++ W ++ R K+E+ PKF ++ Y + ++L ++G LFS Sbjct: 292 YLALEDYLTVDLVETWLQNMKTR----KMEVFFPKFKLNQRYEMHELLKQMGIRRLFSTS 347 Query: 346 ADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFL 404 ADLS ++ + L+ S+ ++ L+VDE GTEA + T I +S ++ NRPF Sbjct: 348 ADLSELSAMARNLQVSRVLQQSVLEVDERGTEAVSGTLSEIIAYSMPPA---IKVNRPFH 404 Query: 405 VVIFSTSTQSVLFLGKVVDPT 425 +I+ ++ +LFLG+VV+PT Sbjct: 405 FIIYEEMSRMLLFLGRVVNPT 425 >2H4Q-A nrPDB Length = 382 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 102/346 (29%), Positives = 171/346 (49%), Gaps = 16/346 (4%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ + +F + + KNIFFSP SIS+A A+ L A + ++ E L F Sbjct: 43 EQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFE 102 Query: 109 LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLF 168 E ++H GF+ LL N P + R + +++ L +L + Y+A+ Sbjct: 103 QAE----NIHSGFKELLTAFNKPRNNYSLRSANRIYVEKTYALLPTYLQLSKKYYKAEPQ 158 Query: 169 HTNFYD-TVGTIQLINDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKALWEKPFIS 225 NF + + IN V+K+T KI +L+ ++K ++LVN IYFKA WE F + Sbjct: 159 KVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDVKATTRLILVNAIYFKAEWEVKFQA 218 Query: 226 SRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDY-KGDATVFFILPNQ- 283 +T+ + F + +N + V MM + ++ + ++ + Y K + ++F +LP+ Sbjct: 219 EKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEK-MNFKMIELPYVKRELSMFILLPDDI 277 Query: 284 ----GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFT 339 + ++E LT E L W + K ++LHLPKFS+ L L +G T Sbjct: 278 KDGTTGLEQLERELTYERLSEWADS--KMMTETLVDLHLPKFSLEDRIDLRDTLRNMGMT 335 Query: 340 DLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAI 385 F+ AD G+T ++ L SK H++ + VDE GTEA AAT+ I Sbjct: 336 TAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGTEAVAATAVII 381 >4KDS-A nrPDB Length = 386 Score = 364 bits (935), Expect = e-101, Method: Composition-based stats. Identities = 103/384 (26%), Positives = 178/384 (46%), Gaps = 21/384 (5%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 + DF R + +A + G N+ FSP ++ AM LGA ++ + LGF+L Sbjct: 15 LQEKQTDFGMRVFSQVAQNSKGSNLAFSPYGVATILAMAQLGAGGNTLKTLNAKLGFSLQ 74 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E + R Q + + G+E S + + + F ++A Sbjct: 75 ERGMARQQRLLQRDISS----EEGVEL--ASGVMVERKMALEKGFRRGLGKAFQASPHQL 128 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRT 228 +F + +IN V T G I +S L + MVL+N ++F+ LW+ PF T Sbjct: 129 DFSRPDQALDIINAWVSDHTAGTIPSFLSSGALTDETRMVLLNALHFQGLWKVPFDPKMT 188 Query: 229 TPKDFYVDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGDA-TVFFILP--NQ 283 + F+ ++V VPMM + ++ + V+ + Y+G++ ++ + P + Sbjct: 189 EERLFHCANGSSVPVPMMRLTHRFKYGEFVTPDGVDYDVIEVPYEGESLSMLLVSPFEPE 248 Query: 284 GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 + + LT + L +W +R K +L LP+F++ L IL ++G D+F+ Sbjct: 249 TPVSSLSSELTTQRLQQWRQEMRS----VKRQLVLPRFTLDSEVELKSILIQMGLGDMFN 304 Query: 344 -KWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRP 402 AD + IT +Q L SK K ++V+E GT+A+AAT+ + A + NRP Sbjct: 305 LAKADFTRITTEQPLCVSKVLQKVKIEVNEEGTKASAATAAILFSRMA---VEEITMNRP 361 Query: 403 FLVVIFSTSTQSVLFLGKVVDPTK 426 FL +I ST +VLF+G+V P + Sbjct: 362 FLFLIHHKSTGAVLFMGQVNQPQQ 385 >3LW2-A nrPDB Length = 379 Score = 363 bits (933), Expect = e-101, Method: Composition-based stats. Identities = 103/381 (27%), Positives = 194/381 (50%), Gaps = 18/381 (4%) Query: 52 APANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE 111 A DF + + + + +N+ FSP +S+ AML + +R QI + +GF + Sbjct: 9 AHQATDFGVKVFQQVVQASKDRNVVFSPYGVSSVLAMLQMTTAGKTRRQIQDAMGF---K 65 Query: 112 LSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTN 171 ++E + L L P + E A+F+ +L+ + F+ +++ + + Sbjct: 66 VNEKGTAHALRQLSKELMGPWNKNEISTADAIFVQRDLELVQGFMPHFFKLFQTMVKQVD 125 Query: 172 FYDTVGTIQLINDHVKKETRGKIVDLVSELKKD--VLMVLVNYIYFKALWEKPFISSRTT 229 F + +IND V++ T+G I DL+++ D +VLVN +YF W+ PF+ + T Sbjct: 126 FSEVERARFIINDWVERHTKGMINDLLAKGAVDELTRLVLVNALYFSGQWKTPFLEASTH 185 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGD-ATVFFILPNQGK- 285 + F+ + +TV VPMM Q + ++ + L V+ + Y+GD ++F P + Sbjct: 186 QRLFHKSDGSTVSVPMMAQSNKFNYTEFTTPDGLEYDVVELPYQGDTLSMFIAAPFEKDV 245 Query: 286 -MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 + + +L E++ +W + + L LPKFS+ L L +LG D+FS Sbjct: 246 HLSALTNILDAELIRQWKGNMTRLPRL----LILPKFSLETEVDLRGPLEKLGMPDMFSA 301 Query: 345 W-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPF 403 AD + ++ Q++L +++ K ++V+E+GT A+++T+F I A T I +R F Sbjct: 302 TLADFTSLSDQEQLSVAQALQKVRIEVNESGTVASSSTAFVISARMAPTEMVI---DRSF 358 Query: 404 LVVIFSTSTQSVLFLGKVVDP 424 L V+ T+++LF+G+V++P Sbjct: 359 LFVVRHNPTETILFMGQVMEP 379 >1HLE-A nrPDB Length = 345 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 110/334 (32%), Positives = 175/334 (52%), Gaps = 19/334 (5%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ AN FA + + P NIF SPLSIS+A AM+ LG ++ +Q+ + L F+ Sbjct: 3 EQLSTANTHFAVDLFRALNESDPTGNIFISPLSISSALAMIFLGTRGNTAAQVSKALYFD 62 Query: 109 LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLF 168 E D+H FQ L +N PG ++ + L+ FLA FL T +Y A+L Sbjct: 63 TVE----DIHSRFQSLNADINKPGAPYILKLANRLYGEKTYNFLADFLASTQKMYGAELA 118 Query: 169 HTNFYD-TVGTIQLINDHVKKETRGKIVDLVSELKKD--VLMVLVNYIYFKALWEKPFIS 225 +F + IN+ VK +T GKI +L+ + D +VLVN IYFK W++ F+ Sbjct: 119 SVDFQQAPEDARKEINEWVKGQTEGKIPELLVKGMVDNMTKLVLVNAIYFKGNWQQKFMK 178 Query: 226 SRTTPKDFYVDENTTVRVPMMLQDQEHHW-YLHDRYLPCSVLRMDYKG-DATVFFILPNQ 283 T F +++ T V MM Q ++ + Y+ D L C VL + Y+G + ++ +LP+ Sbjct: 179 EATRDAPFRLNKKDTKTVKMMYQKKKFPYNYIED--LKCRVLELPYQGKELSMIILLPDD 236 Query: 284 -----GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGF 338 + +IE+ LT + L W + + ++ +HLP+F + SY L L RLG Sbjct: 237 IEDESTGLEKIEKQLTLDKLREWTK--PENLYLAEVNVHLPRFKLEESYDLTSHLARLGV 294 Query: 339 TDLFS-KWADLSGITKQQKLEASKSFHKATLDVD 371 DLF+ ADLSG++ + L SK HK+ +D++ Sbjct: 295 QDLFNRGKADLSGMSGARDLFVSKIIHKSFVDLN 328 >1UHG-A nrPDB Length = 385 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 105/389 (26%), Positives = 178/389 (45%), Gaps = 21/389 (5%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN-- 108 I A+ +F F + + +NIF+ P++I +A AM+ LGA +R+QI + + F+ Sbjct: 3 IGAASMEFCFDVFKELKVHHANENIFYCPIAIMSALAMVYLGAKDSTRTQINKVVRFDKL 62 Query: 109 --------LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTM 160 + +VH + +L+ + P + S L+ L ++L Sbjct: 63 PGFGDSIEAQCGTSVNVHSSLRDILNQITKPNDVYSFSLASRLYAEERYPILPEYLQCVK 122 Query: 161 AVYEAKLFHTNFYDTV-GTIQLINDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKA 217 +Y L NF +LIN V+ +T G I +++ S + MVLVN I FK Sbjct: 123 ELYRGGLEPINFQTAADQARELINSWVESQTNGIIRNVLQPSSVDSQTAMVLVNAIVFKG 182 Query: 218 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDY-KGDATV 276 LWEK F T F V E + V MM Q +L + + G ++ Sbjct: 183 LWEKAFKDEDTQAMPFRVTEQESKPVQMMYQIGLFRVASMASE-KMKILELPFASGTMSM 241 Query: 277 FFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPR 335 +LP++ + ++E ++ E L W + +K++++LP+ + Y L +L Sbjct: 242 LVLLPDEVSGLEQLESIINFEKLTEWTSS--NVMEERKIKVYLPRMKMEEKYNLTSVLMA 299 Query: 336 LGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRH 395 +G TD+FS A+LSGI+ + L+ S++ H A +++EAG E + + S Sbjct: 300 MGITDVFSSSANLSGISSAESLKISQAVHAAHAEINEAGREVVGSAEAGVDAAS---VSE 356 Query: 396 ILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 R + PFL I +T +VLF G+ V P Sbjct: 357 EFRADHPFLFCIKHIATNAVLFFGRCVSP 385 >2H4P-A nrPDB Length = 394 Score = 360 bits (923), Expect = e-100, Method: Composition-based stats. Identities = 103/370 (27%), Positives = 173/370 (46%), Gaps = 36/370 (9%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFN 108 +++ + +F + + KNIFFSP SIS+A A+ L A + ++ E L F Sbjct: 27 EQVSASIGNFTVDLFNKLNETNRDKNIFFSPWSISSALALTYLAAKGSTAREMAEVLHFT 86 Query: 109 LTELSE------------------------SDVHRGFQHLLHTLNLPGHGLETRVGSALF 144 +E ++H GF+ LL N P + R + ++ Sbjct: 87 EAVRAESSSVARPSRGRPKRRRMDPEHEQAENIHSGFKELLTAFNKPRNNYSLRSANRIY 146 Query: 145 LSHNLKFLAKFLNDTMAVYEAKLFHTNFYD-TVGTIQLINDHVKKETRGKIVDLV--SEL 201 + L +L + Y+A+ NF + + IN V+K+T KI +L+ ++ Sbjct: 147 VEKTYALLPTYLQLSKKYYKAEPQKVNFKTAPEQSRKEINTWVEKQTESKIKNLLSSDDV 206 Query: 202 KKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYL 261 K ++LVN IYFKA WE F + +T+ + F + +N + V MM + ++ + Sbjct: 207 KATTRLILVNAIYFKAEWEVKFQAEKTSIQPFRLSKNKSKPVKMMYMRDTFPVLIMEK-M 265 Query: 262 PCSVLRMDY-KGDATVFFILPNQ-----GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLE 315 ++ + Y K + ++F +LP+ + ++E LT E L W + K ++ Sbjct: 266 NFKMIELPYVKRELSMFILLPDDIKDGTTGLEQLERELTYERLSEWADS--KMMTETLVD 323 Query: 316 LHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGT 375 LHLPKFS+ L L +G T F+ AD G+T ++ L SK H++ + VDE GT Sbjct: 324 LHLPKFSLEDRIDLRDTLRNMGMTTAFTTNADFRGMTDKKDLAISKVIHQSFVAVDEKGT 383 Query: 376 EAAAATSFAI 385 EAAAAT+ I Sbjct: 384 EAAAATAVII 393 >4DTE-A nrPDB Length = 374 Score = 353 bits (907), Expect = 7e-98, Method: Composition-based stats. Identities = 90/384 (23%), Positives = 169/384 (44%), Gaps = 21/384 (5%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 I DF + + P +N+ SP I++ M +GA + + +G++L Sbjct: 3 IQDKQTDFGLQVFAEAVQSAPDRNLALSPYGIASVLGMAQMGAYGATLKLLASKMGYSLQ 62 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 E + R Q L G+E V S + + + F +++ Sbjct: 63 ERGMPKLQRLLQRDL----ASEDGVE--VASGVMVDRKIILEKVFRRSLSKAFQSVPHQI 116 Query: 171 NFYDTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRT 228 +F Q+IN T G I + + L + +V +N ++F +W+ PF T Sbjct: 117 DFSQPEMARQVINSWTSDHTDGMISEFLPSGVLSELTRLVFLNALHFHGVWKTPFDPRNT 176 Query: 229 TPKDFYVDENTTVRVPMMLQDQEHHW--YLHDRYLPCSVLRMDYKGDA-TVFFILP--NQ 283 + F+ + V VPMM Q+ ++ ++ + V+ M Y+G++ ++ + P Sbjct: 177 REQLFHTVNGSAVSVPMMTTTQKFNYGEFVSKDGVDYDVIEMPYEGESISMLLVTPFEKD 236 Query: 284 GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 + + + L+ + +W +RK + +L +P+FS+ L L R+G D+FS Sbjct: 237 VPLSALNKELSSSRIHQWRQEMRKISK----QLSIPRFSMDTEIDLKSTLSRMGLGDIFS 292 Query: 344 KW-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRP 402 + AD S IT ++ L SK + L+V+E GT+ ++AT+ I A + +RP Sbjct: 293 QSRADFSRITTEEPLCVSKVLQRVKLEVNEEGTKGSSATAAVIYSRMA---VEEITLDRP 349 Query: 403 FLVVIFSTSTQSVLFLGKVVDPTK 426 F +I T ++LF G++ P + Sbjct: 350 FFFLIQHKPTGALLFSGQLTQPQE 373 >5NCS-A nrPDB Length = 375 Score = 350 bits (898), Expect = 7e-97, Method: Composition-based stats. Identities = 106/378 (28%), Positives = 166/378 (43%), Gaps = 16/378 (4%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 107 S KI NA FAF N+F SPLS+S A M GA + ++ L Sbjct: 5 SEKIEKDNA-FAFDLLQTTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTAL-- 61 Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 T + D++ L L + ++++ F+ Y+A++ Sbjct: 62 RETGYTMEDINEYSHSLREALLKVDPSTTIGMANSIWYKQGELVKEPFILANRTHYDAEV 121 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 227 +F T+ IN ++T KI ++ + + M L+N +YFK +W F S Sbjct: 122 KAVDFSSPA-TLPAINGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSD 180 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA-TVFFILPNQGK- 285 T F + TT V MM Q Y D C L MDY A ++ +LPN+G+ Sbjct: 181 TKRAPFRKADGTTQEVNMMAQKSTF-GYTTDEC--CQYLEMDYGNKAFSMIVMLPNEGQT 237 Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVL-DQILPRLGFTDLFSK 344 R++ E L + W+ +++ ++ L +P+F Y L +ILP +G F++ Sbjct: 238 TRDVIEQLDNK---HWSMIIKGIR-PTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTE 293 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIK-FFSAQTNRHILRFNRPF 403 AD GIT + S+ HK + VDE GTEAAA T+ + S T N+PF Sbjct: 294 TADFPGITDAA-IFISRVIHKTFVQVDEEGTEAAAVTAVEMVKTSSPSTTPINFHINKPF 352 Query: 404 LVVIFSTSTQSVLFLGKV 421 + I ST +LF+G++ Sbjct: 353 VFAIREKSTGVILFIGEI 370 >5INW-A nrPDB Length = 421 Score = 350 bits (898), Expect = 7e-97, Method: Composition-based stats. Identities = 113/344 (32%), Positives = 180/344 (52%), Gaps = 7/344 (2%) Query: 48 SLKIAPANADFAFRFYYL-IASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLG 106 + +IA A FR Y + P NIFFSPLSI++A +++ GA +R+++ LG Sbjct: 78 TQRIASAVNGLGFRLYKQVLGGAGPADNIFFSPLSIASALGVVTAGANGSTRAELDTALG 137 Query: 107 FN--LTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 F L ++ + F L L G E + +F L +F +++ Sbjct: 138 FKEFLHGKKKAKSMKYFARLNGALYKRSAGFELMGKNVVFSKKGLWLYRQFTRTVAHLFK 197 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFI 224 + + +F D+ ++L+N +++K T K D++S++ D +V+VN IYFK W F Sbjct: 198 SNVRSVDFGDSKNAVELMNAYIEKVTSKKFPDVISDVDTDTSLVIVNVIYFKGSWGNKFE 257 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG 284 T F+V+ + ++ VP M Q + Y DR L +V+++ Y+G A++ I+P++ Sbjct: 258 PDLTKNVRFWVNSSYSMMVPTMHQRAKLS-YTQDRKLRSTVVKLPYEGGASMLVIVPHRT 316 Query: 285 K-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 + + ++EE ++ E L W +LL N Y ++L LPKF IS SY L L +G + +FS Sbjct: 317 EDLPKVEESVSQEQLEEWLSLLGPSNHY--VQLSLPKFKISVSYDLKAYLSAMGMSSMFS 374 Query: 344 KWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKF 387 ADLS IT QKL K HK+ L V+E GTEA A T I Sbjct: 375 YGADLSRITGMQKLHVDKITHKSVLHVNEEGTEAKAETVVGIMA 418 >4DY0-A nrPDB Length = 379 Score = 348 bits (892), Expect = 4e-96, Method: Composition-based stats. Identities = 96/387 (24%), Positives = 173/387 (44%), Gaps = 22/387 (5%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 107 L + ++ + + I P NI SP I++ ML LGA ++ Q+ + + Sbjct: 5 PLSLEELGSNTGIQVFNQIVKSRPHDNIVISPHGIASVLGMLQLGADGRTKKQLAMVMRY 64 Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 + V + + + + + V +A+F+ + + F+ V++ ++ Sbjct: 65 GVN-----GVGKILKKINKAIVSKKNKDIVTVANAVFVKNASEIEVPFVTRNKDVFQCEV 119 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKD---VLMVLVNYIYFKALWEKPFI 224 + NF D IN VK ETR I +L+S D +VLVN +YFK LW+ F Sbjct: 120 RNVNFEDPASACDSINAWVKNETRDMIDNLLSPDLIDGVLTRLVLVNAVYFKGLWKSRFQ 179 Query: 225 SSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLP--CSVLRMDYKGDA-TVFFILP 281 T + F + + +VPM+ Q + + + Y G++ ++ LP Sbjct: 180 PENTKKRTFVAADGKSYQVPMLAQLSVFRCGSTSAPNDLWYNFIELPYHGESISMLIALP 239 Query: 282 NQGK--MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFT 339 + + I ++ + + W +++ K++++ LPKF+ L + L LG T Sbjct: 240 TESSTPLSAIIPHISTKTIDSWMSIM----VPKRVQVILPKFTAVAQTDLKEPLKVLGIT 295 Query: 340 DLF-SKWADLSGI-TKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHIL 397 D+F S A+ + I T + L S KA ++V E GT+A+AAT+ + S+ Sbjct: 296 DMFDSSKANFAKITTGSENLHVSHILQKAKIEVSEDGTKASAATTAILIARSSPP---WF 352 Query: 398 RFNRPFLVVIFSTSTQSVLFLGKVVDP 424 +RPFL I T +VLF+G++ P Sbjct: 353 IVDRPFLFFIRHNPTGAVLFMGQINKP 379 >4P0F-A nrPDB Length = 393 Score = 342 bits (877), Expect = 2e-94, Method: Composition-based stats. Identities = 109/387 (28%), Positives = 172/387 (44%), Gaps = 19/387 (4%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEG 104 + + A A F+ Y ++ + PG+NI FSP SI AM LGA + + +Q+ +G Sbjct: 4 DAAHQEFARRLALFSINVYGKLSGQKPGENIVFSPFSIQTCAAMARLGAENETATQLDQG 63 Query: 105 LGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYE 164 LG L+ SD + L R+ + +F+ + +F + Sbjct: 64 LG-----LASSDPEQIAHSFHQVLAAYQDSQILRIANKIFVMDGYQLRQEFDQLLSKQFL 118 Query: 165 AKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKP 222 + +F V IN+ V++ T I DLV L + +VLVN I+FK W+ Sbjct: 119 SAAQSVDFSKNVQAAATINNWVEQRTNHLIKDLVPADVLNSESRLVLVNAIHFKGTWQHQ 178 Query: 223 FISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILP 281 F T P F++D TV+VPMM +E Y L L + YK D ++ +LP Sbjct: 179 FAKHLTRPDTFHLDGERTVQVPMMSL-KERFRYADLPALDAMALELPYKDSDLSMLIVLP 237 Query: 282 N-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTD 340 N + + +EE L L + L + K+ L LP+F L ++ +LG + Sbjct: 238 NTKTGLPALEEKLRLTTLSQITQSL----YETKVALKLPRFKAEFQVELSEVFQKLGMSR 293 Query: 341 LFSKWADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSFAI---KFFSAQTNRHI 396 +FS A+ + + + L+ S HKA ++V+E GTEAAAAT A+ + + Sbjct: 294 MFSDQAEFGKMLQSPEPLKVSAIIHKAFIEVNEEGTEAAAATGMAVRRKRAIMSPEEPIE 353 Query: 397 LRFNRPFLVVIFSTSTQSVLFLGKVVD 423 + PF V+ LF G VV Sbjct: 354 FFADHPFTYVLVHQK-DLPLFWGSVVR 379 >3F02-A nrPDB Length = 359 Score = 336 bits (862), Expect = 1e-92, Method: Composition-based stats. Identities = 90/345 (26%), Positives = 167/345 (48%), Gaps = 15/345 (4%) Query: 53 PANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTEL 112 A AD + Y + + +NI FSPLSI+ A M+ LGA ++ +I +G++ + Sbjct: 21 EAIADLSVNMYNRLRATGEDENILFSPLSIALAMGMMELGAQGSTQKEIRHSMGYDSLKN 80 Query: 113 SESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNF 172 E + + + ++ ++LF+ + +FL + A + H +F Sbjct: 81 GEE--FSFLKEFSNMVTAKESQYVMKIANSLFVQNGFHVNEEFLQMMKKYFNAAVNHVDF 138 Query: 173 YDTVGTIQLINDHVKKETRGKIVDLVS--ELKKDVLMVLVNYIYFKALWEKPFISSRTTP 230 V IN V+ T + DLVS + + L+N +YFK W+ F T Sbjct: 139 SQNVAVANYINKWVENNTNNLVKDLVSPRDFDAATYLALINAVYFKGNWKSQFRPENTRT 198 Query: 231 KDFYVDENTTVRVPMMLQDQEHHWY-LHDRYLPC----SVLRMDYKGD-ATVFFILP-NQ 283 F D+ + V++PMM Q E ++ D VL + Y+GD ++ +L + Sbjct: 199 FSFTKDDESEVQIPMMYQQGEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLVLSRQE 258 Query: 284 GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS 343 + +E ++ +++ W N ++K+ K+E++LP+F++ L +L LG T++F Sbjct: 259 VPLATLEPLVKAQLVEEWANSVKKQ----KVEVYLPRFTVEQEIDLKDVLKALGITEIFI 314 Query: 344 KWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFF 388 K A+L+G++ +++ SK+ HK+ L+V+E G+EAAA + Sbjct: 315 KDANLTGLSDNKEIFLSKAIHKSFLEVNEEGSEAAAVSGMIAISR 359 >1IMV-A nrPDB Length = 398 Score = 335 bits (860), Expect = 2e-92, Method: Composition-based stats. Identities = 105/411 (25%), Positives = 187/411 (45%), Gaps = 16/411 (3%) Query: 19 HGQLHVEHDGESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFS 78 E + S + + + P K+A A ++F + Y + +S +P N+ S Sbjct: 2 PASPPEEGSPDPDSTGALVEEEDPFFKVPVNKLAAAVSNFGYDLYRVRSSMSPTTNVLLS 61 Query: 79 PLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETR 138 PLS++ A + LSLGA + S I L ++L +S D+H ++ LL T+ P + Sbjct: 62 PLSVATALSALSLGADERTESIIHRALYYDL--ISSPDIHGTYKELLDTVTAPQKN--LK 117 Query: 139 VGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLV 198 S + L+ + F+ Y + + +Q IN+ V+ + +GK+ Sbjct: 118 SASRIVFEKKLRIKSSFVAPLEKSYGTRPRVLT-GNPRLDLQEINNWVQAQMKGKLARST 176 Query: 199 SELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHD 258 E+ ++ ++L+ +FK W F S +T+ +DFY+DE TVRVPMM + Y D Sbjct: 177 KEIPDEISILLLGVAHFKGQWVTKFDSRKTSLEDFYLDEERTVRVPMMSDPKAVLRYGLD 236 Query: 259 RYLPCSVLRMDYKGDATVFFILPNQ--GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLEL 316 L C + ++ G ++ F LP + + IEE LT E + + L+ L Sbjct: 237 SDLSCKIAQLPLTGSMSIIFFLPLKVTQNLTLIEESLTSEFIHDIDRELKTVQAV----L 292 Query: 317 HLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTE 376 +PK +S + + L + LF D S IT + ++ ++ H+A + +E G Sbjct: 293 TVPKLKLSYEGEVTKSLQEMKLQSLFDS-PDFSKITG-KPIKLTQVEHRAGFEWNEDGAG 350 Query: 377 AAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPTKP 427 + + + N+PF+ V+ T T ++LF+GK++DP P Sbjct: 351 TTPSPGLQPAHLTFPLDY---HLNQPFIFVLRDTDTGALLFIGKILDPRGP 398 >4AJU-A nrPDB Length = 387 Score = 335 bits (860), Expect = 2e-92, Method: Composition-based stats. Identities = 96/345 (27%), Positives = 165/345 (47%), Gaps = 8/345 (2%) Query: 46 SPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGL 105 + ++A ++F F I+ G N+ FSP +S A L LGA + +QI GL Sbjct: 49 ASRQQLAKETSNFGFSLLRKISMRHDG-NMVFSPFGMSLAMTGLMLGATGPTETQIKRGL 107 Query: 106 GFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEA 165 + ++ + L L GS F+ + F N + ++ Sbjct: 108 HLQALKPTKPGLLPSLFKGLRETLSRNLELGLTQGSFAFIHKDFDVKETFFNLSKRYFDT 167 Query: 166 KLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFIS 225 + NF + +L+N ++ KETRGKI L E+ + ++LV+YI FK W PF Sbjct: 168 ECVPMNFRNASQAKRLMNHYINKETRGKIPKLFDEINPETKLILVDYILFKGKWLTPFDP 227 Query: 226 SRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-G 284 T F++D+ T++VPMM + D+ C VL++ Y+G+AT+ +L + G Sbjct: 228 VFTEVDTFHLDKYKTIKVPMMYGAGKF-ASTFDKNFRCHVLKLPYQGNATMLVVLMEKMG 286 Query: 285 KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK 344 +E+ LT +++ W ++ RN +E+ PKF + Y + ++L ++G +FS Sbjct: 287 DHLALEDYLTTDLVETWLRNMKTRN----MEVFFPKFKLDQKYEMHELLRQMGIRRIFSP 342 Query: 345 WADLSGITKQ-QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFF 388 +ADLS ++ + L+ S+ + ++VDE GTEA A I Sbjct: 343 FADLSELSATGRNLQVSRVLQRTVIEVDERGTEAVAGILSEITAR 387 >3ZHA-A nrPDB Length = 392 Score = 323 bits (829), Expect = 8e-89, Method: Composition-based stats. Identities = 94/382 (24%), Positives = 178/382 (46%), Gaps = 19/382 (4%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 +A +A AF Y +A + +NI SP+ ++++ ++SLG + + SQ L + Sbjct: 9 LAERSAGLAFSLYQAMAKDQAVENILLSPVVVASSLGLVSLGGKATTASQAKAVL--SAE 66 Query: 111 ELSESDVHRGFQHLLHTL-NLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 +L + +VH G LL +L N + ++GS L+ ++ F F+ + Y + Sbjct: 67 QLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFAEDFVRSSKQHYNCEHSK 126 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 NF D +Q IN+ + T GK+ ++ ++++ +LVN ++FK W++ F Sbjct: 127 INFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVD 186 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ--GKMR 287 + F V + TV V MM + +++Y D ++ M + IL + Sbjct: 187 NRGFMVTRSYTVGVTMMHRTGLYNYY-DDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLE 245 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSK-WA 346 +E++LT E L W ++K K + + LPK + ++ L + L LG T+ K A Sbjct: 246 RLEKLLTKEQLKIWMGKMQK----KAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKA 301 Query: 347 DLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT--NRHILRFNRPFL 404 DLS ++ ++ L + FH + D G F + + + + + PF+ Sbjct: 302 DLSRMSGKKDLYLASVFHATAFEWDTEG------NPFDQDIYGREELRSPKLFYADHPFI 355 Query: 405 VVIFSTSTQSVLFLGKVVDPTK 426 ++ T + S+LF+G++V P Sbjct: 356 FLVRDTQSGSLLFIGRLVRPKG 377 >2R9Y-A nrPDB Length = 430 Score = 323 bits (828), Expect = 8e-89, Method: Composition-based stats. Identities = 103/383 (26%), Positives = 165/383 (43%), Gaps = 23/383 (6%) Query: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILE 103 + ++A A F + L+A + N+ SPLS++ A + L+LGA + + + Sbjct: 14 TAEETRRLAQAMMAFTTDLFSLVAQTSTSSNLVLSPLSVALALSHLALGAQNQTLHSLHR 73 Query: 104 GLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVY 163 L N + S + H L R+ + ++L FL + ++ Sbjct: 74 VLHMN----TGSCLPHLLSHFYQNLG----PGTIRLAARIYLQKGFPIKDDFLEQSERLF 125 Query: 164 EAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPF 223 AK + IN VK+ T GKI D +SEL +++L+N I+F W F Sbjct: 126 GAKPVKLTGKQ-EEDLANINQWVKEATEGKIEDFLSELPDSTVLLLLNAIHFHGFWRTKF 184 Query: 224 ISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPN- 282 S T F++DE TV V MM + V +K + + ++P Sbjct: 185 DPSLTQKDFFHLDERFTVSVDMMHAVSYPLRWFLLEQPEIQVAHFPFKNNMSFVVVMPTY 244 Query: 283 -QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDL 341 + + E+ LT W+ L + ++ LPK + L L +LG +L Sbjct: 245 FEWNVSEVLANLT------WDTLYHPSLQERPTKVWLPKLHLQQQLDLVATLSQLGLQEL 298 Query: 342 FSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNR 401 F + DL GI+ +Q L S H++T+++ EAG EAAAATS A+ S + NR Sbjct: 299 F-QGPDLRGIS-EQNLVVSSVQHQSTMELSEAGVEAAAATSVAMNRMSLSS----FTVNR 352 Query: 402 PFLVVIFSTSTQSVLFLGKVVDP 424 PFL I + LF+G V +P Sbjct: 353 PFLFFIMEDTIGVPLFVGSVRNP 375 >1XQJ-A nrPDB Length = 389 Score = 321 bits (823), Expect = 3e-88, Method: Composition-based stats. Identities = 91/384 (23%), Positives = 175/384 (45%), Gaps = 22/384 (5%) Query: 51 IAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLT 110 + AN+ FA + ++ + P N+ FSP+++S + ++ +GA + ++I + L F Sbjct: 18 LQLANSAFAVDLFKQLSEKEPLGNVLFSPIALSTSLSLAQVGAKGDTANEIGQVLHFENV 77 Query: 111 ELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHT 170 + DV GFQ + +N ++ L++ +L +F++ T Y +L Sbjct: 78 K----DVPFGFQTVTSDVNKLSSFYSLKLIKRLYVDKSLNLSTEFISSTKRPYAKELETV 133 Query: 171 NFYDT-VGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSR 227 +F D T IN+ +K T G +++++ + +++VN YF W K F S Sbjct: 134 DFKDKLEETKGQINNSIKDLTDGHFENILADNSVNDQTKILVVNAAYFVGKWMKKFSESE 193 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG-DATVFFILPNQ--- 283 T F V++ T V MM + D + ++ + ++ ++F +LP Sbjct: 194 TKESPFRVNKTDTKPVQMMNMEATFSMGNIDS-INSKIIELPFQNKHLSMFILLPKDVED 252 Query: 284 --GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDL 341 + +IE+ L E L +W N N K++L +PKF + L LG + Sbjct: 253 ESTGLEKIEKQLNSESLSQWTNPSTMANA--KVKLSIPKFKVEKMIDPKASLENLGLKHI 310 Query: 342 FSKW-ADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFN 400 FS+ +D SG+++ + + S HK +L++ E G ++ I ++ L + Sbjct: 311 FSEDTSDFSGMSETKGVALSNVIHKVSLEITEDGGDSIEVPGARIL-----QHKDELNAD 365 Query: 401 RPFLVVIFSTSTQSVLFLGKVVDP 424 PF+ +I T++++F GK P Sbjct: 366 HPFIYIIRHNKTRNIIFFGKFSSP 389 >5NCU-A nrPDB Length = 336 Score = 313 bits (802), Expect = 1e-85, Method: Composition-based stats. Identities = 95/342 (27%), Positives = 149/342 (43%), Gaps = 15/342 (4%) Query: 48 SLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGF 107 S KI NA FAF N+F SPLS+S A M GA + ++ L Sbjct: 5 SEKIEKDNA-FAFDLLQTTRKHVTEANVFISPLSVSMALNMTLNGAAGVTADEMKTAL-- 61 Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 T + D++ L L + ++++ F+ Y+A++ Sbjct: 62 RETGYTMEDINEYSHSLREALLKVDPSTTIGMANSIWYKQGELVKEPFILANRTHYDAEV 121 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSR 227 +F T+ IN ++T KI ++ + + M L+N +YFK +W F S Sbjct: 122 KAVDFSSPA-TLPAINGWCAQKTNDKITKILDYIPGNAFMYLINAVYFKGIWVTQFKKSD 180 Query: 228 TTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA-TVFFILPNQGK- 285 T F + TT V MM Q Y D C L MDY A ++ +LPN+G+ Sbjct: 181 TKRAPFRKADGTTQEVNMMAQKSTF-GYTTDEC--CQYLEMDYGNKAFSMIVMLPNEGQT 237 Query: 286 MREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVL-DQILPRLGFTDLFSK 344 R++ E L + W+ +++ ++ L +P+F Y L +ILP +G F++ Sbjct: 238 TRDVIEQLDNK---HWSMIIKGIR-PTQVSLRMPRFKTECKYGLEKKILPEMGMNVPFTE 293 Query: 345 WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIK 386 AD GIT + S+ HK + VDE GTEAAA T+ + Sbjct: 294 TADFPGITDAA-IFISRVIHKTFVQVDEEGTEAAAVTAVEMV 334 >3LE2-A nrPDB Length = 393 Score = 304 bits (779), Expect = 4e-83, Method: Composition-based stats. Identities = 100/377 (26%), Positives = 171/377 (45%), Gaps = 23/377 (6%) Query: 64 YLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQH 123 ++I + + N+ FSP SI+ ++++ G+ ++ QIL L F+ T+ S Sbjct: 22 HVITTVSQNSNVIFSPASINVVLSIIAAGSAGATKDQILSFLKFSSTDQLNSFSSEIVSA 81 Query: 124 LLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY-DTVGTIQLI 182 +L + G G + V + ++ +L F F Y+A +F V I + Sbjct: 82 VLADGSANG-GPKLSVANGAWIDKSLSFKPSFKQLLEDSYKAASNQADFQSKAVEVIAEV 140 Query: 183 NDHVKKETRGKIVDLVSELKKD--VLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTT 240 N +KET G I +++ E D ++ N +YFK W + F S T +F++ + Sbjct: 141 NSWAEKETNGLITEVLPEGSADSMTKLIFANALYFKGTWNEKFDESLTQEGEFHLLDGNK 200 Query: 241 VRVPMMLQDQEHHWYLHDRYLPCSVLRMDY-----KGDATVFFILPNQGK--MREIEEVL 293 V P M ++ + +D VL + Y K +++F LP+ +++++ Sbjct: 201 VTAPFMTSKKKQYVSAYD---GFKVLGLPYLQGQDKRQFSMYFYLPDANNGLSDLLDKIV 257 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 + + R K E +PKF S + +L LG T FS L+ + + Sbjct: 258 STPGF---LDNHIPRRQVKVREFKIPKFKFSFGFDASNVLKGLGLTSPFSGEEGLTEMVE 314 Query: 354 Q----QKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NRPFLVVI 407 + L S FHKA ++V+E GTEAAAA++ IK + F + PFL+V+ Sbjct: 315 SPEMGKNLCVSNIFHKACIEVNEEGTEAAAASAGVIKLRGLLMEEDEIDFVADHPFLLVV 374 Query: 408 FSTSTQSVLFLGKVVDP 424 T VLF+G+VVDP Sbjct: 375 TENITGVVLFIGQVVDP 391 >2PEF-A nrPDB Length = 373 Score = 303 bits (776), Expect = 1e-82, Method: Composition-based stats. Identities = 95/374 (25%), Positives = 157/374 (41%), Gaps = 18/374 (4%) Query: 54 ANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELS 113 ADF+ + S +N SPLS A AM + GA + + +Q+ + LG ++S Sbjct: 12 NTADFSIELFK--NSIDDKENSLISPLSAMLALAMTANGADNETLAQMEKALG---KDIS 66 Query: 114 ESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY 173 D+++ + L T S F ++ FL Y+A +F F Sbjct: 67 IEDLNKYLYTYMKKLPNEEKSKLTIANSIWFKENDFMPSKDFLQIIADYYKADIFKAAF- 125 Query: 174 DTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDF 233 T+ IN+ VK +T G I +++++ + +M L+N + F A WE + + F Sbjct: 126 -DSSTVSDINNWVKSKTNGMIDKILNKIDPEDVMYLINAVAFDAEWETVYEKASVHEDIF 184 Query: 234 YVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQG-KMREIEEV 292 +V M ++ + + ++ K + ILP++ + E + Sbjct: 185 TDVYGNRQKVEFMNSEENLYI---EEENAVGFVKPYAKNHYSFVAILPDENISVNEYIKT 241 Query: 293 LTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLF-SKWADLSGI 351 LT + + L K + LPKF + +++ L LG TD F AD S + Sbjct: 242 LTGQKFID----LIKNAKITLVRASLPKFKYEYTIKMNETLESLGMTDAFLPDKADFSKL 297 Query: 352 TKQQ--KLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFS 409 K L S+ HK + VDE GT+A A TS I N ++ NRPF+ I Sbjct: 298 GKSDIGNLYISEVLHKTFISVDELGTKAGAVTSVDITAAGIPVNFKTVKLNRPFIFAIID 357 Query: 410 TSTQSVLFLGKVVD 423 ST +F+G V+ Sbjct: 358 NSTNLPIFIGTVLS 371 >1K9O-I nrPDB Length = 378 Score = 300 bits (769), Expect = 6e-82, Method: Composition-based stats. Identities = 106/392 (27%), Positives = 190/392 (48%), Gaps = 26/392 (6%) Query: 43 GEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQIL 102 GE + +N F + + + PG+N+ S S+ L+L + S ++L Sbjct: 3 GETDLQKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELL 62 Query: 103 EGLGF---NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDT 159 L N+T+ +D++RG + + G++ ++ S ++++ L+ F + Sbjct: 63 RALALPNDNVTKDVFADLNRGVRAV--------KGVDLKMASKIYVAKGLELNDDFAAVS 114 Query: 160 MAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKA 217 V+ +++ + +F +V IN V+ +T +I +LV L + VLVN IYFK Sbjct: 115 RDVFGSEVQNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKG 174 Query: 218 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATV 276 W+ F+ RT +DF+V ++ T++VP M+ ++ Y L ++ M Y+GD A++ Sbjct: 175 SWKDKFVKERTMDRDFHVSKDKTIKVPTMIGKKDVR-YADVPELDAKMIEMSYEGDQASM 233 Query: 277 FFILPNQ-GKMREIEEVL-TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILP 334 ILPNQ + +E+ L P+ L R +R + ++E+ LPKF I + L ++L Sbjct: 234 IIILPNQVDGITALEQKLKDPKALSR----AEERLYNTEVEITLPKFKIETTTDLKEVLS 289 Query: 335 RLGFTDLFSKW-ADLSGITKQQ-KLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT 392 + LF+ A L + K + L + KA ++V+E G EAAAA +F I S Sbjct: 290 NMNIKKLFTPGAARLENLLKTKESLTVDAAIQKAFIEVNEEGAEAAAANAFGIVPKSLIL 349 Query: 393 NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 + +RPF + +F GKV++P Sbjct: 350 YPE-VHIDRPFYFEL--KIDGIPMFNGKVIEP 378 >6CJ7-A nrPDB Length = 390 Score = 299 bits (767), Expect = 1e-81, Method: Composition-based stats. Identities = 100/380 (26%), Positives = 172/380 (45%), Gaps = 18/380 (4%) Query: 52 APANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE 111 PA+ F + +A+E G N+ SP SI+ AML GA ++ +I L + Sbjct: 14 GPASTSFGVNVFKQMATEQSG-NLAASPFSITILLAMLQQGAAGNTLDEITRALQMTPEK 72 Query: 112 LSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTN 171 +E F+ + + + + +FLS N +F + +++ L T Sbjct: 73 SAE-----IFKKVNEEIQKRNSRNILKTANNVFLSENFNLNPQFKRIAVNNFDSDLTPTY 127 Query: 172 FYDTVGTIQLINDHVKKETRGKIVDLV--SELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 F Q IN + +T KI LV +L + MV+VN +YFK LWE PF T Sbjct: 128 FGKPALAAQNINSWIASKTNDKIDKLVSPDDLSGNTQMVMVNAVYFKGLWEIPFREQATQ 187 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYK-GDATVFFILP-NQGKMR 287 ++F ++ M Q + + + V+ + ++ + ++ +LP + Sbjct: 188 KRNFTLNGGEKKVASFM-QTRRYFKAGTHKPAMAKVVVLPFEYNEYSLIVVLPLKSSNVD 246 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 347 + L+ E + + +L K + L LPKFSI L+ +L ++G + +F++ A+ Sbjct: 247 ALLSSLSMEDVASFLDL-----PPKDVALELPKFSIKADINLEPVLNKMGVSSIFTQQAE 301 Query: 348 LSGITKQQKL--EASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLV 405 L + L + S + H A L +DE G AAAATSFA S R N+PFL Sbjct: 302 LYNLGSHGSLSPQVSSALHSAVLTIDERGGSAAAATSFAAVALSYDEPSLYFRANKPFLA 361 Query: 406 VIFSTSTQSVLFLGKVVDPT 425 +++ + LF+ +++DPT Sbjct: 362 ILWDNRSSIPLFMARIMDPT 381 >3OZQ-A nrPDB Length = 376 Score = 294 bits (752), Expect = 7e-80, Method: Composition-based stats. Identities = 93/384 (24%), Positives = 157/384 (40%), Gaps = 21/384 (5%) Query: 44 EGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILE 103 E + + A F Y + +T N SP S + A+ G + +I + Sbjct: 4 EDATLQEFPNAVNSFTPSVYKEV-LKTEKANFLVSPFSAATLLALAQSGCRGDTAEEIRQ 62 Query: 104 GLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVY 163 L F + +L L + +++ N +F + VY Sbjct: 63 VLHFVGD---REKAEGAVKEVLSKLTNEE--YTLHTANKIYVKTNFSVREEFQKIAVEVY 117 Query: 164 EAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEK 221 A+ + +F + +L+N V+++T+ KI +LV L +VL+N +YF A W Sbjct: 118 GAQSENVDFSEKNDAAKLMNAWVEEQTQHKIQNLVDPEILNNLTRVVLINALYFNAKWLV 177 Query: 222 PFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILP 281 PF T DF+ V+V M D+++ Y +L +L + +KG A++ +L Sbjct: 178 PFPPFHTRKSDFHKSAKEVVQVDTMYLDEQYFNYYECHHLDAKLLELPFKGGASLTIVLS 237 Query: 282 NQ-GKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTD 340 NQ + +E + L + + + LPKF I + ++L +LG Sbjct: 238 NQIEGLVSLESKIKRSFLPH-------NLTKQLVNVALPKFKIESTVDFKKVLKKLGVKK 290 Query: 341 LFSKWADLSGITKQQ-KLEASKSFHKATLDVDEAGTEAAAATSFAIKF--FSAQTNRHIL 397 F ADLSGI ++ L S K+ +DV E G EAAAAT + + + Sbjct: 291 AFGDEADLSGIAGEKGDLVISNIVQKSFIDVSEEGVEAAAATYIPVILPEMALPDSPKQF 350 Query: 398 RFNRPFLVVIFSTSTQSVLFLGKV 421 + PF+ I +LF G+V Sbjct: 351 IVDHPFIFYI--KVKGMILFAGRV 372 >1SEK-A nrPDB Length = 378 Score = 292 bits (748), Expect = 2e-79, Method: Composition-based stats. Identities = 105/392 (26%), Positives = 189/392 (48%), Gaps = 26/392 (6%) Query: 43 GEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQIL 102 GE + +N F + + + PG+N+ S S+ L+L + S ++L Sbjct: 3 GETDLQKILRESNDQFTAQMFSEVVKANPGQNVVLSAFSVLPPLGQLALASVGESHDELL 62 Query: 103 EGLGF---NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDT 159 L N+T+ +D++RG + + G++ ++ S ++++ L+ F + Sbjct: 63 RALALPNDNVTKDVFADLNRGVRAV--------KGVDLKMASKIYVAKGLELNDDFAAVS 114 Query: 160 MAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKA 217 V+ +++ + +F +V IN V+ +T +I +LV L + VLVN IYFK Sbjct: 115 RDVFGSEVQNVDFVKSVEAAGAINKWVEDQTNNRIKNLVDPDALDETTRSVLVNAIYFKG 174 Query: 218 LWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGD-ATV 276 W+ F RT +DF+V ++ T++VP M+ ++ Y L ++ M Y+GD A++ Sbjct: 175 SWKDKFNKERTMDRDFHVSKDKTIKVPTMIGKKDVR-YADVPELDAKMIEMSYEGDQASM 233 Query: 277 FFILPNQ-GKMREIEEVL-TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILP 334 ILPNQ + +E+ L P+ L R +R + ++E++LPKF I + L ++L Sbjct: 234 IIILPNQVDGITALEQKLKDPKALSR----AEERLYNTEVEIYLPKFKIETTTDLKEVLS 289 Query: 335 RLGFTDLFSKW-ADLSGITKQQ-KLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQT 392 + LF+ A L + K + L + KA ++V+E G EAAAA +F I +S Sbjct: 290 NMNIKKLFTPGAARLENLLKTKESLYVDAAIQKAFIEVNEEGAEAAAANAFKITTYSFHF 349 Query: 393 NRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 + N+PF + + +F G V P Sbjct: 350 VPK-VEINKPFFFSLKYNR--NSMFSGVCVQP 378 >3PZF-A nrPDB Length = 397 Score = 287 bits (735), Expect = 6e-78, Method: Composition-based stats. Identities = 90/411 (21%), Positives = 174/411 (42%), Gaps = 31/411 (7%) Query: 28 GESCSNSSHQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYA 87 G + Q + +G +F F I N+ SP S+ Sbjct: 2 GHHHHHHGQQDVHGPFQG-------QRQNEFDLMFVKEIFKNH-NSNVVLSPFSVKILLT 53 Query: 88 MLSLG-------ACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVG 140 ++ A S+++ ++ + + + + S ++ LL + + + Sbjct: 54 LIYEASDTSFGNAVSNTKRELSSVIQNDNIDHTRS----YYKQLLESAQQDNKDYDLNIA 109 Query: 141 SALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLV-S 199 + F+ ++ + K+ Y A L ++ + T IN+ V + T G++ ++V Sbjct: 110 TNFFVDDFIEVINKYQQIANTHYHAMLEKVSYSNPTQTAATINNWVSEHTNGRLREIVTP 169 Query: 200 ELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDR 259 + + ++ LVN IYFK LW PF K FY M Q+ + +Y + Sbjct: 170 DSLEGAVITLVNVIYFKGLWTYPFPEVANNVKPFYGTRGKPTNAQYMEQNGQF-YYDNSA 228 Query: 260 YLPCSVLRMDYKGD-ATVFFILPNQGK-MREIEEVLTPEMLMRWNNLLRKRNFYKKLELH 317 L +LR+ Y+G+ ++FILPN + ++ + + L + + + ++ + Sbjct: 229 DLGAQILRLPYRGNKLAMYFILPNPDNTVNQVLDRINSASLHQALWYMEEN----EVNVT 284 Query: 318 LPKFSISGSYVLDQILPRLGFTDLFSKWADLS----GITKQQKLEASKSFHKATLDVDEA 373 LPKF S L++ L ++G ++FS+ A L G + ++ S+ F KA + ++E Sbjct: 285 LPKFKFDFSEQLNEPLQQVGIREIFSQNASLPLLARGRGARDEVRVSRIFQKAGITINEL 344 Query: 374 GTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 G+EA AAT + I NRPF+ I + ++LF GK+ +P Sbjct: 345 GSEAYAATEIQLVNKFGGDGVQIFNANRPFIFFIEDETLGTMLFAGKIENP 395 >2OAY-A nrPDB Length = 390 Score = 286 bits (733), Expect = 9e-78, Method: Composition-based stats. Identities = 91/378 (24%), Positives = 168/378 (44%), Gaps = 23/378 (6%) Query: 51 IAPANADFAFRFYYLI-ASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNL 109 + A DF+ + Y+ A + N+ FSP SI++ + LGA ++++ + L + Sbjct: 32 LGDALVDFSLKLYHAFSAMKKVETNMAFSPFSIASLLTQVLLGAGENTKTNLESILSYPK 91 Query: 110 TELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFH 169 +GF S +F S +L F+N + +Y + Sbjct: 92 DFTCVHQALKGFTT-----------KGVTSVSQIFHSPDLAIRDTFVNASRTLYSSSPRV 140 Query: 170 TNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTT 229 + ++ ++LIN V K T KI L+ L D +VL+N IY A W+ F +T Sbjct: 141 LS-NNSDANLELINTWVAKNTNNKISRLLDSLPSDTRLVLLNAIYLSAKWKTTFDPKKTR 199 Query: 230 PKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGK--MR 287 + F+ +N+ ++VPMM + + D+ L V ++ + ++ ++P K + Sbjct: 200 MEPFHF-KNSVIKVPMMNSKKYPVAHFIDQTLKAKVGQLQLSHNLSLVILVPQNLKHRLE 258 Query: 288 EIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWAD 347 ++E+ L+P + L F L L LP+ ++ S + I+ +L F D FS + Sbjct: 259 DMEQALSPSVFKAIMEKLEMSKFQPTL-LTLPRIKVTTSQDMLSIMEKLEFFD-FSYDLN 316 Query: 348 LSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVI 407 L G+T+ L+ S H+ L++ E G E + A S + +PFL ++ Sbjct: 317 LCGLTEDPDLQVSAMQHQTVLELTETGVE-----AAAASAISVARTLLVFEVQQPFLFML 371 Query: 408 FSTSTQSVLFLGKVVDPT 425 + + +F+G+V DP Sbjct: 372 WDQQHKFPVFMGRVYDPR 389 >3STO-A nrPDB Length = 406 Score = 279 bits (715), Expect = 1e-75, Method: Composition-based stats. Identities = 91/393 (23%), Positives = 153/393 (38%), Gaps = 34/393 (8%) Query: 50 KIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAML--SLGACSHSRSQILEG--L 105 ++ ADF G N PL I +L S GA + QI + L Sbjct: 26 YLSTVTADFG------------GDNFLTCPLGILFTLGILLGSGGAQGRTGYQIGKTMRL 73 Query: 106 GFNLTELSESDVHRGFQHLLHTLNLPGHGLET----------RVGSALFLSHNLKFLAKF 155 + + S+ + + L LN +T R+ + +F+ + +F Sbjct: 74 KSTSSSWNSSEAQQEMKSLYQELNNSLTSEKTFLNEKEENVVRISTGIFVEKTYEVERRF 133 Query: 156 LNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLV-SELKKDVLMVLVNYIY 214 E +L +F + IND V +++ G + ++ D M+LVN Y Sbjct: 134 NESIANDSEGELKQVDFSNRTSATVDINDWVDQQSNGLLEKFFTDDIPDDTAMILVNVFY 193 Query: 215 FKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDA 274 F+ W+ PF T +DFY+ + + V MM Q+ + + V + Sbjct: 194 FRDFWQSPFEPHYTRKEDFYISPDRQITVDMMTQEGVMKYGKFEDEGFEIVSKPLNNTRF 253 Query: 275 TVFFILP-NQGKMREIEEVLT-PEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQI 332 T +LP + + E+L ++L + L++ + L LPKF++ + L Sbjct: 254 TFVIVLPLEKWSLNGATELLNGNKVLSEYVKNLKE----TTVSLRLPKFTLKNTLDLVPT 309 Query: 333 LPRLGFTDLFSK-WADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQ 391 L +G DLF +DLSGIT L ++ L ++E+G EA TS FSA Sbjct: 310 LKSIGVVDLFDPVKSDLSGITPNPNLYVNEFIQTNVLKLNESGIEATTVTSPIFVPFSAI 369 Query: 392 TNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDP 424 PF+ I+ + KV++P Sbjct: 370 IPEVDFHVTHPFICFIYDQQLTMPIMAAKVMNP 402 >1C8O-A nrPDB Length = 300 Score = 276 bits (706), Expect = 1e-74, Method: Composition-based stats. Identities = 89/328 (27%), Positives = 149/328 (45%), Gaps = 33/328 (10%) Query: 60 FRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHR 119 + IAS G+N+F SP SIS+ +L GA + Q+ Sbjct: 1 MDIFREIASSMKGENVFISPPSISSVLTILYYGANGSTAEQLS----------------- 43 Query: 120 GFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTI 179 +++ + + + + ++ ++ F FL ++ +F D+ T+ Sbjct: 44 --KYVEKEADKNKDDISFKSMNKVYGRYSAVFKDSFLRKIGDNFQ----TVDFTDS-RTV 96 Query: 180 QLINDHVKKETRGKIVDLVSE-LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDEN 238 IN V T GKI L+ E L D ++ ++ +YFKA W PF T+ FYV Sbjct: 97 DAINKSVDIFTEGKINPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPT 156 Query: 239 TTVRVPMMLQDQE--HHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GKMREIEEVLTP 295 V V MM E +H + + + S++ + Y GD ++ ILP+ + IE+ LT Sbjct: 157 EMVDVSMMSMYGEAFNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTD 216 Query: 296 EMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQ 355 +W++ + +++H+PKF ++GSY L L +LG T++F D S ++ Sbjct: 217 TNFKKWSDSMDAM----FIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNS- 271 Query: 356 KLEASKSFHKATLDVDEAGTEAAAATSF 383 + HK +DV+E TEAAAATS Sbjct: 272 DVSVDAMIHKTYIDVNEEYTEAAAATSA 299 >1SNG-A nrPDB Length = 370 Score = 271 bits (692), Expect = 5e-73, Method: Composition-based stats. Identities = 94/376 (25%), Positives = 165/376 (43%), Gaps = 30/376 (7%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 +FA + +A P + +SP S++ A +L+ GA + +R+++ LG + L + Sbjct: 16 EFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAPLLAA- 74 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY-DT 175 L L +R + L++S ++ + F ++ + +F + Sbjct: 75 --------LDRAVTDSPDLASR--TVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNP 124 Query: 176 VGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDF 233 G +N + TRG I +L+ + + D+ +L N ++ KA W PF + T F Sbjct: 125 EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTRAGTF 184 Query: 234 YVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVL 293 RVP M + + + + ++ + + V +LP + Sbjct: 185 RTPRGP-KRVPFMHRTKTMPYATARGW---RMVTLHAHDELAVDVLLPPGTNAAAV---P 237 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 T +L L +R+ +EL LP+F ++ + L ++L G LF+ ADLSGI+ Sbjct: 238 TAPLL----TALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGIS- 292 Query: 354 QQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRF--NRPFLVVIFSTS 411 L H+A L VDE G E AAAT+ + A R +RF +RPF +V+ Sbjct: 293 TVPLYVDTVIHQARLRVDERGAEGAAATAAMMLLAGAMPPRRTIRFSVDRPFHIVVRRR- 351 Query: 412 TQSVLFLGKVVDPTKP 427 ++LFLG + DP P Sbjct: 352 -GAILFLGSIADPHDP 366 >1JJO-C nrPDB Length = 261 Score = 264 bits (675), Expect = 5e-71, Method: Composition-based stats. Identities = 73/264 (27%), Positives = 133/264 (50%), Gaps = 13/264 (4%) Query: 132 GHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETR 191 + ++ ++LF+ + +FL + A++ H +F V IN V+ T Sbjct: 1 ENQYVMKLANSLFVQNGFHVNEEFLQMLKMYFNAEVNHVDFSQNVAVANSINKWVENYTN 60 Query: 192 GKIVDLVSELKKD--VLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQD 249 + DLVS D + L+N +YFK W+ F T F D+ + V++PMM Q Sbjct: 61 SLLKDLVSPEDFDGVTNLALINAVYFKGNWKSQFRPENTRTFSFTKDDESEVQIPMMYQQ 120 Query: 250 QEHHWY-LHDRYLPC----SVLRMDYKGD-ATVFFILP-NQGKMREIEEVLTPEMLMRWN 302 E ++ D VL + Y+GD ++ L + + +E +L +++ W Sbjct: 121 GEFYYGEFSDGSNEAGGIYQVLEIPYEGDEISMMLALSRQEVPLATLEPLLKAQLIEEWA 180 Query: 303 NLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKS 362 N ++K+ K+E++LP+F++ L IL LG T++F K A+L+ ++ +++L SK+ Sbjct: 181 NSVKKQ----KVEVYLPRFTVEQEIDLKDILKALGVTEIFIKDANLTAMSDKKELFLSKA 236 Query: 363 FHKATLDVDEAGTEAAAATSFAIK 386 HK+ ++V+E G+EAAAA+ Sbjct: 237 VHKSCIEVNEEGSEAAAASGMIAI 260 >2WXX-A nrPDB Length = 453 Score = 255 bits (651), Expect = 3e-68, Method: Composition-based stats. Identities = 82/406 (20%), Positives = 149/406 (36%), Gaps = 29/406 (7%) Query: 36 HQQILETGEGSPSLKIAPANADFAFRFYYLIASETPGKN-IFFSPLSISAAYAMLSLGAC 94 + LE + + ++A FR Y ++ G + SP ++ LG+ Sbjct: 58 AAEKLEDEDRKRAAQVAMITNFVGFRMYKMLNEAGSGASGAILSPPALFGTLVSFYLGSL 117 Query: 95 SHSRSQILEGLGFNLTE---LSESDVHRGFQHLLHTL--------NLPGHGLETRVGSAL 143 + SQ+ L + E S D H+ L + L + L Sbjct: 118 DPTASQLQTLLDVPVKEGDCTSRLDGHKVLAALRAVQGLLVTQGGSSSQTPLLQSIVVGL 177 Query: 144 FLSHNLKFLAKFLNDTMAVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSE 200 F + + F+ A++ LF + D V + IN +K T K+ + Sbjct: 178 FTAPGFRLKHSFVQSL-ALFTPALFPRSLDLSTDPVLATEKINRFIKAVTGWKMNLPLEG 236 Query: 201 LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRY 260 + D ++ Y++F+ S +F+VD + +V VPM+ + D Sbjct: 237 VSTDSTLLFNTYVHFQGTMRG--FSQLPGVHEFWVDNSISVSVPMISGTGNFQ-HWSDAQ 293 Query: 261 LPCSVLRMDYKGDATVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLP 319 SV + AT+ I P+ + +E ++ L+ W + + + L LP Sbjct: 294 NNFSVTCVPLGERATLLLIQPHCISDLDRVEALIFQNDLLTWI----ENPPPRAIRLTLP 349 Query: 320 KFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAA 379 + I GSY L +L L A+L+ I + + L++ +AG E Sbjct: 350 QLEIRGSYNLQDLLAEDKLPTLLGAEANLNNIGDTNP-RVGEVLNSILLEL-KAGEEEQP 407 Query: 380 ATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPT 425 TS + + PFL I+ + ++ FLG+V +P Sbjct: 408 TTSVQQPG---SPEALDVTLSSPFLFAIYEQDSGTLHFLGRVNNPQ 450 >2WXZ-C nrPDB Length = 453 Score = 253 bits (647), Expect = 9e-68, Method: Composition-based stats. Identities = 82/406 (20%), Positives = 146/406 (35%), Gaps = 29/406 (7%) Query: 36 HQQILETGEGSPSLKIAPANADFAFRFYYLIASE-TPGKNIFFSPLSISAAYAMLSLGAC 94 + LE + + ++A FR Y +++ SP ++ LG+ Sbjct: 58 ATEKLEAEDRQRAAQVAMIANFMGFRMYKMLSEARGVASGAVLSPPALFGTLVSFYLGSL 117 Query: 95 SHSRSQILEGLGFNLTE---LSESDVHRGFQHLLHTL--------NLPGHGLETRVGSAL 143 + SQ+ LG + E S D H+ L + L L Sbjct: 118 DPTASQLQVLLGVPVKEGDCTSRLDGHKVLTALQAVQGLLVTQGGSSSQTPLLQSTVVGL 177 Query: 144 FLSHNLKFLAKFLNDTMAVYEAKLFHTNF---YDTVGTIQLINDHVKKETRGKIVDLVSE 200 F + L+ F+ + +F + D V Q IN V+ T K+ + Sbjct: 178 FTAPGLRLKQPFVESL-GPFTPAIFPRSLDLSTDPVLAAQKINRFVQAVTGWKMNLPLEG 236 Query: 201 LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRY 260 + D + Y++F+ S T +F+VD +T+V VPM+ + D Sbjct: 237 VSTDSTLFFNTYVHFQGKMRG--FSQLTGLHEFWVDNSTSVSVPMLSGTGNFQ-HWSDAQ 293 Query: 261 LPCSVLRMDYKGDATVFFILPN-QGKMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLP 319 SV R+ T+ I P + +E ++ + W K + + L LP Sbjct: 294 NNFSVTRVPLGESVTLLLIQPQCASDLDRVEVLVFQHDFLTWI----KNPPPRAIRLTLP 349 Query: 320 KFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAA 379 + I GSY L +L + + L A+L + + + L++ +AG E Sbjct: 350 QLEIRGSYNLQDLLAQAKLSTLLGAEANLGKMGDTNP-RVGEVLNSILLEL-QAGEEEQP 407 Query: 380 ATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKVVDPT 425 S + + PFL I+ + ++ FLG+V +P Sbjct: 408 TESAQQPG---SPEVLDVTLSSPFLFAIYERDSGALHFLGRVDNPQ 450 >5C98-A nrPDB Length = 382 Score = 249 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 82/395 (20%), Positives = 138/395 (34%), Gaps = 36/395 (9%) Query: 45 GSPSLKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLS--LGACSHSRSQIL 102 G P+ A A+ F Y A N SP + A +M GA Q+ Sbjct: 9 GDPTTDDAIVAANNKFTLEYFKACYDEKCNCAVSPYHVRLALSMFYPLAGAAVQEDFQVA 68 Query: 103 EGLGFNLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAV 162 GL DVH + G + S + + L+ ++F Sbjct: 69 FGL--------PEDVHAAIEQQQRLAQQLHDGQHLKALSFVLVEETLRLDSEFERLFHRT 120 Query: 163 YEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKP 222 ++ + + D + + +N + +I D + E L + F + Sbjct: 121 FQTTVEPVDLTDDIPSALAVNSF-YQRANTEIEDFIGEGDVFSLPPCHKLMLFSGVSVLT 179 Query: 223 -----FISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKG--DAT 275 F + T + F T RV M LH+ L C V+ M + + Sbjct: 180 PLAIRFNPADTALELFQFINAPTQRVSTMHTTAFVRRCLHNE-LRCKVVDMPFDAASGLS 238 Query: 276 VFFILPNQG-KMREIEEVLTPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILP 334 + +LP G ++R+I +TP L + + L+ +L LPKF + Q L Sbjct: 239 MLVLLPYDGTELRQIVNSITPAHLAQIDERLQS----CWTDLKLPKFFVREKTDPKQTLG 294 Query: 335 RLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNR 394 +LG+ +F + DL + + L V E+G+ A + Sbjct: 295 KLGYGGVF-EIDDLHVFHDSGRTRLNGFIQHCYLAVSESGSGIPAPPDT--------PSE 345 Query: 395 HILRFNRPFLVVIFSTSTQSVLFLG---KVVDPTK 426 NRPF+ +I T +VL +G K +DP + Sbjct: 346 FEFHANRPFMFLIRRTMDGNVLQVGNFSKYIDPDE 380 >5M3Y-A nrPDB Length = 458 Score = 238 bits (607), Expect = 4e-63, Method: Composition-based stats. Identities = 70/363 (19%), Positives = 139/363 (38%), Gaps = 28/363 (7%) Query: 76 FFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE---LSESDVHRGFQHLLHTLNL-- 130 SP ++ A L LGA H+ ++ LG + S D H+ L L Sbjct: 100 VLSPTAVFGTLASLYLGALDHTADRLQAILGVPWKDKQCTSRLDAHKVLSALQAVQGLLV 159 Query: 131 ------PGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL--FHTNFYDTVGTIQLI 182 L +F + L F+ A+Y + +F + + I Sbjct: 160 AQGRADSQAQLLLSTVVGVFTAPGLHLKQPFVQGL-ALYTPVVLPRSLDFTELDVAAEKI 218 Query: 183 NDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVR 242 + ++ T K + D + Y++F+ + S P++F+VD++T+V Sbjct: 219 DRFMQAVTGWKTGSSLMGASVDSTLAFNTYVHFQGKMKG--FSLLAEPQEFWVDQSTSVS 276 Query: 243 VPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GKMREIEEVLTPEMLMRW 301 VPM+ + D SV ++ + A++ I P+ + ++E + + + W Sbjct: 277 VPMLSGMGTFQ-HWSDIQDQFSVTQVPFTESASLLLIQPHYASDLDKVEGLTFQQNSLNW 335 Query: 302 NNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASK 361 L R + L +P+ + GSY L +L + + +L ++ ++ + Sbjct: 336 MKKLSPRT----IHLTMPQLVLQGSYDLQDLLAQAELPAILHTELNLQKLSND-RIRVGE 390 Query: 362 SFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLFLGKV 421 + +++ E +T K + NRPFL ++ S ++ FLG+V Sbjct: 391 VLNSIFFELEADEREPTESTQQLNK-----PEVLEVTLNRPFLFAVYDQSATALHFLGRV 445 Query: 422 VDP 424 +P Sbjct: 446 ANP 448 >1MTP-A nrPDB Length = 323 Score = 235 bits (599), Expect = 3e-62, Method: Composition-based stats. Identities = 73/320 (22%), Positives = 135/320 (42%), Gaps = 26/320 (8%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESD 116 +FA + +A P + +SP S++ A +L+ GA + +R+++ LG + L + Sbjct: 12 EFALHLHRRLAEAVPDGEVIWSPYSVACALGVLAAGARATTRTELTTLLGTDPAPLLAA- 70 Query: 117 VHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFY-DT 175 L L +R + L++S ++ + F ++ + +F + Sbjct: 71 --------LDRAVTDSPDLASR--TVLWVSADVPVRSSFRATMHDRPDSDVRTADFRTNP 120 Query: 176 VGTIQLINDHVKKETRGKIVDLVSE--LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDF 233 G +N + TRG I +L+ + + D+ +L N ++ KA W PF + T F Sbjct: 121 EGVRATVNADIADATRGMIRELLPQGAVTPDLRAILTNALWAKARWTTPFEAHLTREGTF 180 Query: 234 YVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFFILPNQGKMREIEEVL 293 RVP M + + + + ++ + + V +LP + Sbjct: 181 RTPRGP-KRVPFMHRTKTMPYATARGW---RMVTLHAHDELAVDVLLPPGTNAAAV---P 233 Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 T +L L +R+ +EL LP+F ++ + L ++L G LF+ ADLSGI+ Sbjct: 234 TAPLL----TALHRRSASTSVELALPRFELTQPHQLVEVLAEAGVRTLFTASADLSGIS- 288 Query: 354 QQKLEASKSFHKATLDVDEA 373 L H+A L VDE Sbjct: 289 TVPLYVDTVIHQARLRVDER 308 >6BJ5-B nrPDB Length = 315 Score = 231 bits (589), Expect = 5e-61, Method: Composition-based stats. Identities = 72/319 (22%), Positives = 133/319 (41%), Gaps = 35/319 (10%) Query: 69 ETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHTL 128 N+ FSP +++A ++L + A +++ +I + + +SD + L Sbjct: 27 YNESDNVVFSPYGLTSALSVLRIAAGGNTKREI----DVPESVVEDSDAFLALREL---- 78 Query: 129 NLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKK 188 F+ ++ +F + + + + F ++ +IN +VK Sbjct: 79 ---------------FVDASVPLRPEFTAEFSSRFNTSVQRVTF-NSENVKDVINSYVKD 122 Query: 189 ETRGKIVDLVS-ELKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMML 247 +T G + ++ L +D M+L++ + K W F S TT + FY N T +V MM Sbjct: 123 KTGGDVPRVLDASLDRDTKMLLLSSVRMKTSWRHVFDPSFTTDQPFY-SGNVTYKVRMMN 181 Query: 248 Q-DQEHHWYLHDRYLPCSVLRMDYKGDAT-VFFILPNQGKMREIEEVLTPEMLMRWNNLL 305 + D R + SV + YK T + ++P+ + EI L ++ W + Sbjct: 182 KIDTLKTETFTLRNVGYSVTELPYKRRQTAMLLVVPDD--LGEIVRALDLSLVRFWIRNM 239 Query: 306 RKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFS-KWADLSGITKQQKLEASKSFH 364 RK ++ +PKFS+ L L RLG D F AD + L +K Sbjct: 240 RK----DVCQVVMPKFSVESVLDLRDALQRLGVRDAFDPSRADFGQASPSNDLYVTKVLQ 295 Query: 365 KATLDVDEAGTEAAAATSF 383 + ++ DE GT A++ T+ Sbjct: 296 TSKIEADERGTTASSDTAI 314 >1M93-B nrPDB Length = 245 Score = 231 bits (588), Expect = 7e-61, Method: Composition-based stats. Identities = 74/254 (29%), Positives = 123/254 (48%), Gaps = 14/254 (5%) Query: 134 GLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGK 193 + + + ++ ++ F FL ++ +F D+ T+ IN V T GK Sbjct: 1 DISFKSMNKVYGRYSAVFKDSFLRKIGDNFQ----TVDFTDS-RTVDAINKSVDIFTEGK 55 Query: 194 IVDLVSE-LKKDVLMVLVNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQE- 251 I L+ E L D ++ ++ +YFKA W PF T+ FYV V V MM E Sbjct: 56 INPLLDEPLSPDTSLLAISAVYFKAKWLMPFEKEFTSDYPFYVSPTEMVDVSMMSMYGEA 115 Query: 252 -HHWYLHDRYLPCSVLRMDYKGDATVFFILPNQ-GKMREIEEVLTPEMLMRWNNLLRKRN 309 +H + + + S++ + Y GD ++ ILP+ + IE+ LT +W++ + Sbjct: 116 FNHASVKESFGNFSIIELPYVGDTSMVVILPDNIDGLESIEQNLTDTNFKKWSDSMDAM- 174 Query: 310 FYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLD 369 +++H+PKF ++GSY L L +LG T++F D S ++ + HK +D Sbjct: 175 ---FIDVHIPKFKVTGSYNLVDALVKLGLTEVFGSTGDYSNMSNS-DVSVDAMIHKTYID 230 Query: 370 VDEAGTEAAAATSF 383 V+E TEAAAATS Sbjct: 231 VNEEYTEAAAATSA 244 >4R9I-A nrPDB Length = 378 Score = 85.8 bits (211), Expect = 3e-17, Method: Composition-based stats. Identities = 61/366 (16%), Positives = 120/366 (32%), Gaps = 31/366 (8%) Query: 68 SETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTELSESDVHRGFQHLLHT 127 P +N F + + + LSL + + ++ L NL SE +V Q + Sbjct: 34 QYEPERNQFSTAFPLLFMLSELSLNSKEDTTAE----LYKNLNLRSEDEVVNVNQAVNTN 89 Query: 128 LNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVK 187 LN ++ + + + F F+ + V+ + + ++ + + I D ++ Sbjct: 90 LNTKNEVYQSTLILNAYTDIDSPFSETFIQNFAKVFNGTVKNIDYSN--DAVATIRDSLQ 147 Query: 188 KETRGKIVDLVSELK--KDVLMVLVNY--IYFK-ALWEKPFISSRTTPKDFYVDENTTVR 242 ++ I + + KD ++L Y IYF + + F + T Sbjct: 148 SDSGNDIEIALKDGDINKDTGIILTAYTNIYFPWGEASDSYRPYKQIDISFTALDGTQSN 207 Query: 243 VPMMLQDQEHHWYLHDRYLPCSVLRMDYKGDATVFF--ILPNQGKMREIEEVL-TPEMLM 299 + Y L V + K TV L + + L P L Sbjct: 208 KQAWYSEGAGK-YAEIENLGIKVFQFSLKPGLTVVLGTSLNDNNDLSGAFNKLRDPATLA 266 Query: 300 RWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGF-TDLFSKWAD-LSGITKQQKL 357 + + + L ++ S + R G T+LF K D + + Sbjct: 267 YILTQTESKYLKLAVPIEL---TMRDSRDYIPEVKRAGLLTELFEKNFDGFDTVYDNKSG 323 Query: 358 EASKSFHKATLDVDEAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVLF 417 S L+ E TE AA+ A F++P+ ++ + F Sbjct: 324 YISYMLSHTRLEF-EQPTEEQAASVVA---------EPDFIFDKPYFFLVLDQF-NTPAF 372 Query: 418 LGKVVD 423 +G + + Sbjct: 373 IGLITN 378 >3HSI-A nrPDB Length = 458 Score = 35.7 bits (81), Expect = 0.042, Method: Composition-based stats. Identities = 33/169 (19%), Positives = 56/169 (33%), Gaps = 28/169 (16%) Query: 57 DFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGACSHSRSQILEGLGFNLTE----- 111 D A Y + S N+ LS+S + LGA + +Q++E L + + Sbjct: 225 DLAQNGEYSLKSAVKLPNV----LSVSPLFG---LGASGNELNQVIEDLFLQVQKKLVIC 277 Query: 112 LSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKLFHTN 171 + R QH + TL G +E VG + + F Y + Sbjct: 278 TPYFNFPRTLQHKIATLLENGKRVEIIVGDKVANDFYIPPEQPFKMAGALPYLYESNLRR 337 Query: 172 FYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKALWE 220 F + T + E+ +V L + N + K +W Sbjct: 338 FCEKFET--------QIESGQLVVRLWRDGD--------NTYHLKGVWV 370 >4P2L-A nrPDB Length = 506 Score = 32.2 bits (72), Expect = 0.43, Method: Composition-based stats. Identities = 21/110 (19%), Positives = 37/110 (33%), Gaps = 31/110 (28%) Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 + +++ +D+ ++L LE L L KF+ + + Sbjct: 255 DRSKIYMADLESALHYILRVEVGKFSVLE---------GQRLVALKKFVAVLAKYFPGQP 305 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVLVNYIYFKA 217 NF + IND ++K+ + KI Y YFKA Sbjct: 306 LVQNF------LHSINDWLQKQQKKKIP----------------YSYFKA 333 >1F2V-A nrPDB Length = 219 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 20/45 (44%) Query: 49 LKIAPANADFAFRFYYLIASETPGKNIFFSPLSISAAYAMLSLGA 93 + + AD A R + S + FSP +S+A A L GA Sbjct: 37 SRFSEEEADLAVRMVHACGSVEATRQFVFSPDFVSSARAALKAGA 81 >4NOV-A nrPDB Length = 345 Score = 30.7 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 11/53 (20%), Positives = 19/53 (35%), Gaps = 7/53 (13%) Query: 213 IYFKALWEKPFISSRTTPKDFYVDE-----NTTVRVPMMLQDQEHHWYLHDRY 260 +YF+ + T K F+ + T PM+ D + + HD Sbjct: 25 LYFQGS--GAMTETMTEEKTFHKNPIIKDIYTADPAPMVYGDTLYLYTTHDED 75 >3T59-A nrPDB Length = 519 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 32/88 (36%), Gaps = 15/88 (17%) Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 + +++ +D+ ++L LE L L KF+ + + Sbjct: 267 DRSKIYMADLESALHYILRVEVGKFSVLE---------GQRLVALKKFVAVLAKYFPGQP 317 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIV 195 NF + IND ++K+ + +I Sbjct: 318 LVQNF------LHSINDWLQKQQKKRIP 339 >5NSQ-A nrPDB Length = 521 Score = 30.3 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 18/32 (56%), Gaps = 2/32 (6%) Query: 347 DLSGITKQQKLEASKSFHKATLDVDEAGTEAA 378 D++ +T Q + + H A L V+E G EAA Sbjct: 398 DMATLTGAQGIATGR--HHAGLYVNEEGAEAA 427 >6IRX-A nrPDB Length = 496 Score = 29.5 bits (65), Expect = 3.1, Method: Composition-based stats. Identities = 17/92 (18%), Positives = 26/92 (28%), Gaps = 9/92 (9%) Query: 210 VNYIYFKALWEKPFISSRTTPKDFYVDENTTVRVPMMLQDQEHHWYLHDRYLPCSVLRMD 269 +++I F W P + T + + M H Y C + Sbjct: 407 LSFIIFVPEWRDPPTPALTRMEASRFRRHQ------MTVPAFEHEYRSGSQHICKREEIY 460 Query: 270 YKG-DATVFFILPNQGKMREIEEVLTPEMLMR 300 YK T L N + E T E + Sbjct: 461 YKAIHGTAVIFLQNNAGFAKWEP--TTERIQE 490 >3LLI-A nrPDB Length = 261 Score = 29.5 bits (65), Expect = 3.2, Method: Composition-based stats. Identities = 15/88 (17%), Positives = 32/88 (36%), Gaps = 15/88 (17%) Query: 108 NLTELSESDVHRGFQHLLHTLNLPGHGLETRVGSALFLSHNLKFLAKFLNDTMAVYEAKL 167 + +++ +D+ ++L LE L L KF+ + + Sbjct: 10 DRSKIYMADLESALHYILRIEVGRFPVLE---------GQRLVALKKFVAVLAKYFPGRP 60 Query: 168 FHTNFYDTVGTIQLINDHVKKETRGKIV 195 NF + +N+ +K++ R KI Sbjct: 61 LVQNF------LHSVNEWLKRQKRNKIP 82 >2PFD-A nrPDB Length = 541 Score = 29.2 bits (64), Expect = 4.0, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%) Query: 156 LNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIVDLVSELKKDVLMVL 209 L E +F F + + +D K++TR +I L+ E K +VL Sbjct: 480 LQVAAKALETGVFGAYFNVLINLKDMTDDVFKEKTRHRISSLLQEAKTQAALVL 533 >3PPS-A nrPDB Length = 604 Score = 29.2 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 12/75 (16%), Positives = 26/75 (34%), Gaps = 7/75 (9%) Query: 290 EEVLTPEMLMRWNNLLRKRNFYKKLELHLPK-FSISGSYVLD-----QILPRLGFTDLFS 343 + ++ + + +W L + + + + LP + G L LP G +F Sbjct: 443 DNIVQVDAVDQWTYWLIENDPTNPI-VSLPHPMHLHGHDFLVLGRSPDELPSAGVRHIFD 501 Query: 344 KWADLSGITKQQKLE 358 DL + + Sbjct: 502 PAKDLPRLKGNNPVR 516 >1VCN-A nrPDB Length = 550 Score = 28.8 bits (63), Expect = 4.2, Method: Composition-based stats. Identities = 13/71 (18%), Positives = 26/71 (36%), Gaps = 11/71 (15%) Query: 364 HKATLDVD-------EAGTEAAAATSFAIKFFSAQTNRHILRFNRPFLVVIFSTSTQSVL 416 H+ +V+ E +AT+ ++ A I + PF + + S Sbjct: 469 HRHRYEVNPLYVDGLERAGLVVSATTPGMRGRGAGLVEAIELKDHPFFLGLQSHPE---- 524 Query: 417 FLGKVVDPTKP 427 F + + P+ P Sbjct: 525 FKSRPMRPSPP 535 >4OVR-A nrPDB Length = 322 Score = 28.8 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 10/41 (24%), Positives = 18/41 (43%), Gaps = 1/41 (2%) Query: 155 FLNDTMAVYEAKLFHTNFYDTVGTIQLINDHVKKETRGKIV 195 + A + ++ V +Q ++D + KET GKI Sbjct: 19 YFQSMRQYRSADVQPADYPT-VKAVQSMSDELNKETNGKIS 58 >1RKT-A nrPDB Length = 205 Score = 28.8 bits (63), Expect = 5.0, Method: Composition-based stats. Identities = 26/114 (22%), Positives = 41/114 (35%), Gaps = 29/114 (25%) Query: 284 GKMREIEEVLTPEMLM----RWNNLLRKRNFYKKLELHLPKFSI-------SGSYVLDQI 332 +R++ + L P W N R++ K+ +L + +FS G + Q Sbjct: 97 EGLRDVADTLAPVQFEYLVTAWRNEERRQYLEKRYDLFVERFSRLLQKGIDQGEFQPVQP 156 Query: 333 LPR-----LGFTD-------LFSK-WADLSGITKQQKLEASKSFHKATLDVDEA 373 L L D F + AD+SG+ + KL K L DE Sbjct: 157 LATIAKFFLNMNDGIIQNALYFDEEKADVSGLAESAKLYL-----KTVLQADEK 205 >4K8L-A nrPDB Length = 344 Score = 28.8 bits (63), Expect = 5.2, Method: Composition-based stats. Identities = 9/70 (12%), Positives = 23/70 (32%), Gaps = 11/70 (15%) Query: 294 TPEMLMRWNNLLRKRNFYKKLELHLPKFSISGSYVLDQILPRLGFTDLFSKWADLSGITK 353 + E L + + ++ + L +P ++GF + + AD ++ Sbjct: 44 SDETLRNFVLNEPRGGVFRHVNLLVP---------PKDPRAQMGF--IIMEPADTPPMSG 92 Query: 354 QQKLEASKSF 363 + S Sbjct: 93 SNSICVSTVL 102 >4HW8-A nrPDB Length = 420 Score = 28.0 bits (61), Expect = 8.5, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 27/78 (34%), Gaps = 6/78 (7%) Query: 330 DQILPRLGFTDLFSKWADLSGITKQQKLEASKSFHKATLDVDEAGTEAAAA--TSFAIKF 387 Q L + + +K L I + L +K K E EA AA T K Sbjct: 129 KQALKAMNYD---NKQLALPAIVETTALFYNKKLVKNAPQTLEE-VEANAAKLTDSKKKQ 184 Query: 388 FSAQTNRHILRFNRPFLV 405 + + FN PFL Sbjct: 185 YGMLFDAKNFYFNYPFLF 202 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.144 0.410 Lambda K H 0.267 0.0441 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,007,137 Number of Sequences: 36641 Number of extensions: 683625 Number of successful extensions: 2321 Number of sequences better than 10.0: 81 Number of HSP's better than 10.0 without gapping: 128 Number of HSP's successfully gapped in prelim test: 28 Number of HSP's that attempted gapping in prelim test: 1673 Number of HSP's gapped (non-prelim): 171 length of query: 427 length of database: 10,336,785 effective HSP length: 100 effective length of query: 327 effective length of database: 6,672,685 effective search space: 2181967995 effective search space used: 2181967995 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 61 (28.0 bits)