BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P29509 (319 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3D8X-A nrPDB 655 0.0 5W4C-A nrPDB 464 e-131 6BPY-A nrPDB 459 e-130 1VDC-A nrPDB 395 e-111 4CBQ-A nrPDB 392 e-109 2WHD-A nrPDB 374 e-104 6BWT-A nrPDB 307 4e-84 1F6M-A nrPDB 293 9e-80 5UTH-A nrPDB 293 9e-80 5U63-A nrPDB 292 1e-79 5USX-A nrPDB 287 5e-78 2A87-A nrPDB 286 6e-78 4JNQ-A nrPDB 243 7e-65 5M5J-A nrPDB 241 4e-64 5MJK-A nrPDB 233 8e-62 2Q7V-A nrPDB 231 4e-61 4GCM-A nrPDB 211 4e-55 5UWY-A nrPDB 207 5e-54 3ISH-A nrPDB 194 6e-50 4ZN0-A nrPDB 187 5e-48 3F8P-A nrPDB 179 1e-45 3R9U-A nrPDB 170 7e-43 1FL2-A nrPDB 134 6e-32 4YKF-A nrPDB 133 1e-31 3LZX-A nrPDB 67 1e-11 2ZBW-A nrPDB 65 3e-11 5YGQ-A nrPDB 64 7e-11 6GAS-A nrPDB 61 6e-10 4YRY-B nrPDB 60 1e-09 6GAR-A nrPDB 57 1e-08 5JFC-L nrPDB 56 2e-08 5VDN-A nrPDB 54 1e-07 2CVJ-A nrPDB 52 2e-07 1ZK7-A nrPDB 52 4e-07 5VJ7-A nrPDB 48 6e-06 5U1O-A nrPDB 47 9e-06 5XHU-A nrPDB 47 2e-05 3AB1-A nrPDB 46 2e-05 3CGD-A nrPDB 45 4e-05 5V36-A nrPDB 45 5e-05 2R9Z-A nrPDB 44 7e-05 3Q6J-A nrPDB 44 9e-05 4EMJ-A nrPDB 44 1e-04 2X8H-A nrPDB 43 1e-04 4FK1-A nrPDB 43 2e-04 5TR3-A nrPDB 43 2e-04 1YQZ-A nrPDB 42 3e-04 3OC4-A nrPDB 41 6e-04 2AAQ-A nrPDB 41 8e-04 2BC1-A nrPDB 40 0.001 6DU7-A nrPDB 40 0.001 4DNA-A nrPDB 39 0.002 4LA1-A nrPDB 39 0.002 5W1J-A nrPDB 39 0.003 1GEU-A nrPDB 39 0.003 5TWC-A nrPDB 39 0.003 4NTC-A nrPDB 38 0.006 4KPR-E nrPDB 37 0.008 4YWO-A nrPDB 37 0.013 2EQ6-A nrPDB 36 0.019 1NHQ-A nrPDB 36 0.019 6N7F-A nrPDB 35 0.038 5NMX-A nrPDB 35 0.038 6B4O-A nrPDB 34 0.066 3LAD-A nrPDB 34 0.082 1EBD-A nrPDB 34 0.087 2CFY-A nrPDB 33 0.20 5U8W-A nrPDB 32 0.32 2QAE-A nrPDB 31 0.54 1ONF-A nrPDB 31 0.70 2YAU-A nrPDB 31 0.79 2BXR-A nrPDB 31 0.91 3L8K-A nrPDB 30 0.93 4QB5-A nrPDB 30 1.6 3WE0-A nrPDB 29 2.2 4Y4M-A nrPDB 29 2.7 5JCN-A nrPDB 29 2.7 5VHF-V nrPDB 29 3.2 1ZDL-A nrPDB 29 3.3 6FEA-B nrPDB 28 3.6 1LQU-A nrPDB 28 3.8 2WOV-A nrPDB 28 4.6 6EPE-S nrPDB 28 5.9 5J5Z-A nrPDB 28 6.3 5TUF-A nrPDB 28 6.4 3A9C-A nrPDB 28 6.5 3LXD-A nrPDB 28 7.3 4Y4N-A nrPDB 28 7.3 3II4-A nrPDB 27 9.4 >3D8X-A nrPDB Length = 326 Score = 655 bits (1690), Expect = 0.0, Method: Compositional matrix adjust. Identities = 318/318 (100%), Positives = 318/318 (100%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG Sbjct: 9 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 68 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA Sbjct: 69 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 128 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF Sbjct: 129 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 188 Query: 182 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 241 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV Sbjct: 189 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 248 Query: 242 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA Sbjct: 249 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 308 Query: 302 GSGCMAALDAEKYLTSLE 319 GSGCMAALDAEKYLTSLE Sbjct: 309 GSGCMAALDAEKYLTSLE 326 >5W4C-A nrPDB Length = 371 Score = 464 bits (1195), Expect = e-131, Method: Compositional matrix adjust. Identities = 224/319 (70%), Positives = 265/319 (83%), Gaps = 1/319 (0%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 +H+KV IIGSGP HTAAIYLARA ++P+LYEGM+ANG A GGQLTTTT++ENFPGFP+G Sbjct: 29 MHSKVVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLTTTTDVENFPGFPEG 88 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEP-VTTDAIILATG 120 +TG+E+MD+ R QS +FGT+IITETV++VDLS +PFK WTE E+ +T D IILATG Sbjct: 89 VTGTEMMDKFRAQSERFGTKIITETVARVDLSVRPFKYWTEGEEEEHEFMTADTIILATG 148 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ASAKR+ LPGEETYWQ GISACAVCDGAVPIFR KPLAVIGGGDSA EEA +LTKYGS V Sbjct: 149 ASAKRLFLPGEETYWQSGISACAVCDGAVPIFRQKPLAVIGGGDSAAEEATYLTKYGSHV 208 Query: 181 FMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLP 240 ++LVR+D LRAS IM KR + K+ +L+NTVA EAKGDG++L +L IKNTK E DLP Sbjct: 209 YVLVRRDELRASKIMAKRLTSHPKVTVLWNTVATEAKGDGEVLTSLTIKNTKTGETGDLP 268 Query: 241 VSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITS 300 V+GLFYAIGH PAT +V QV+ D GYIKTVPG+S TSV G FAAGDVQD KYRQAITS Sbjct: 269 VNGLFYAIGHEPATSLVKSQVELDSDGYIKTVPGTSQTSVHGVFAAGDVQDKKYRQAITS 328 Query: 301 AGSGCMAALDAEKYLTSLE 319 AGSGC+AAL+AE+ ++ E Sbjct: 329 AGSGCIAALEAERLISEEE 347 >6BPY-A nrPDB Length = 374 Score = 459 bits (1180), Expect = e-130, Method: Compositional matrix adjust. Identities = 223/321 (69%), Positives = 263/321 (81%), Gaps = 6/321 (1%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 MVH KV IIGSGPAAHTAAIYL+RAE+KP+LYEGM+ANG AAGGQLTTTT+IENFPGFPD Sbjct: 2 MVHTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFPD 61 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNE--DAEP-VTTDAIIL 117 G+ G+ELM+ MR+QS +FGTE+ITET+S+VDLSSKPFKLWTE+N+ D EP T DA+I+ Sbjct: 62 GIGGAELMENMRKQSIRFGTEVITETISRVDLSSKPFKLWTEWNDGPDKEPACTADAVII 121 Query: 118 ATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 ATGA+A+R++LPGEETYWQ GISACAVCDGAVPIFRNKPL VIGGGDSA EEA FL KYG Sbjct: 122 ATGANARRLNLPGEETYWQNGISACAVCDGAVPIFRNKPLYVIGGGDSAAEEAMFLAKYG 181 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGK---LLNALRIKNTKKN 234 S V +LVR+D LRAS M KR + K+ + +NTVA E G+ K L+ LRIKNT Sbjct: 182 SSVTVLVRRDKLRASKAMAKRLLAHPKVTVRFNTVATEVLGEKKPNGLMTHLRIKNTVTG 241 Query: 235 EETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 EE + +GLFYA+GH PAT +V GQ+D DE GYI T PG+S TS G FA GDVQD +Y Sbjct: 242 EEEIVDANGLFYAVGHDPATALVKGQIDLDEDGYIITKPGTSYTSREGVFACGDVQDKRY 301 Query: 295 RQAITSAGSGCMAALDAEKYL 315 RQAITSAGSGC+AAL+AEK++ Sbjct: 302 RQAITSAGSGCIAALEAEKFI 322 >1VDC-A nrPDB Length = 333 Score = 395 bits (1016), Expect = e-111, Method: Compositional matrix adjust. Identities = 203/323 (62%), Positives = 251/323 (77%), Gaps = 11/323 (3%) Query: 3 HN-KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 HN ++ I+GSGPAAHTAAIY ARAE+KP+L+EG MAN IA GGQLTTTT++ENFPGFP+G Sbjct: 7 HNTRLCIVGSGPAAHTAAIYAARAELKPLLFEGWMANDIAPGGQLTTTTDVENFPGFPEG 66 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 + G EL D+ R+QS +FGT I TETV+KVD SSKPFKL+T D++ + DA+ILA GA Sbjct: 67 ILGVELTDKFRKQSERFGTTIFTETVTKVDFSSKPFKLFT----DSKAILADAVILAIGA 122 Query: 122 SAKRMHLPGEET----YWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 AKR+ G +W +GISACAVCDGA PIFRNKPLAVIGGGDSA EEA FLTKYG Sbjct: 123 VAKRLSFVGSGEVLGGFWNRGISACAVCDGAAPIFRNKPLAVIGGGDSAMEEANFLTKYG 182 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGK--LLNALRIKNTKKNE 235 SKV+++ R+D RAS IMQ+RA N KI++++N+ +EA GDG+ +L L++KN + Sbjct: 183 SKVYIIHRRDAFRASKIMQQRALSNPKIDVIWNSSVVEAYGDGERDVLGGLKVKNVVTGD 242 Query: 236 ETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYR 295 +DL VSGLF+AIGH PATK + G V+ D GY+ T PG++ TSVPG FAAGDVQD KYR Sbjct: 243 VSDLKVSGLFFAIGHEPATKFLDGGVELDSDGYVVTKPGTTQTSVPGVFAAGDVQDKKYR 302 Query: 296 QAITSAGSGCMAALDAEKYLTSL 318 QAIT+AG+GCMAALDAE YL + Sbjct: 303 QAITAAGTGCMAALDAEHYLQEI 325 >4CBQ-A nrPDB Length = 314 Score = 392 bits (1007), Expect = e-109, Method: Compositional matrix adjust. Identities = 191/314 (60%), Positives = 236/314 (75%), Gaps = 5/314 (1%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 + V IIGSGPAAHTAAIYL R+ +KP++YEG MA G+AAGGQLTTTT IENFPGFP+G+ Sbjct: 5 HDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGID 64 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 G+ELM MR QS K+GT IITET+ VD S++PFKL F E+ + V T ++I+ATGA+A Sbjct: 65 GNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKL---FTEEGKEVLTKSVIIATGATA 121 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 KRMH+PGE+ YWQ G+SACA+CDGAVPIFRNK L V+GGGD+A EEA LTKYGSKV +L Sbjct: 122 KRMHVPGEDKYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIIL 181 Query: 184 VRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 R+D RAS MQ+R + KIE+++N+ +E +GDG LLN +I N E +PV+G Sbjct: 182 HRRDAFRASKTMQERVLNHPKIEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAG 241 Query: 244 LFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGS 303 LFYAIGH+P +K + GQV T + GYI T TSV G FA GDV D YRQAI +AGS Sbjct: 242 LFYAIGHSPNSKFLGGQVKTADDGYILTE--GPKTSVDGVFACGDVCDRVYRQAIVAAGS 299 Query: 304 GCMAALDAEKYLTS 317 GCMAAL EK+L + Sbjct: 300 GCMAALSCEKWLQT 313 >2WHD-A nrPDB Length = 351 Score = 374 bits (961), Expect = e-104, Method: Compositional matrix adjust. Identities = 189/316 (59%), Positives = 241/316 (76%), Gaps = 6/316 (1%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 + +V IIGSGPAAHTAAIY ARAE+KP+L+EG MAN IAAGGQLTTTT++ENFPGFP G Sbjct: 29 LRTRVCIIGSGPAAHTAAIYAARAELKPVLFEGWMANDIAAGGQLTTTTDVENFPGFPTG 88 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 + G +LMD R QS +FGT I++ETV++VD S++PF++ D+ V D +++ATGA Sbjct: 89 IMGIDLMDNCRAQSVRFGTNILSETVTEVDFSARPFRV----TSDSTTVLADTVVVATGA 144 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 A+R++ G +TYW +GISACAVCDGA PIFRNKP+AVIGGGDSA EE FLTKYGS+V+ Sbjct: 145 VARRLYFSGSDTYWNRGISACAVCDGAAPIFRNKPIAVIGGGDSAMEEGNFLTKYGSQVY 204 Query: 182 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE--AKGDGKLLNALRIKNTKKNEETDL 239 ++ R++ RAS IMQ RA N KI++++++ +E G L +++KN E +DL Sbjct: 205 IIHRRNTFRASKIMQARALSNPKIQVVWDSEVVEAYGGAGGGPLAGVKVKNLVTGEVSDL 264 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 VSGLF+AIGH PATK + GQ++ GY+ T PGS+ TSV G FAAGDVQD KYRQAIT Sbjct: 265 QVSGLFFAIGHEPATKFLNGQLELHADGYVATKPGSTHTSVEGVFAAGDVQDKKYRQAIT 324 Query: 300 SAGSGCMAALDAEKYL 315 +AGSGCMAALDAE YL Sbjct: 325 AAGSGCMAALDAEHYL 340 >6BWT-A nrPDB Length = 319 Score = 307 bits (787), Expect = 4e-84, Method: Compositional matrix adjust. Identities = 163/324 (50%), Positives = 224/324 (69%), Gaps = 19/324 (5%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H+K+ I+GSGPA +TAAIY ARA +KP++ GM GGQLTTTT++ N+PG PDG+ Sbjct: 7 HHKLIILGSGPAGYTAAIYAARANLKPVIITGMQP-----GGQLTTTTDVYNWPGEPDGI 61 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 G ELM+++++Q+ +F T+I+ +T++ VDL +KPFKL E E T D +I+ATGA+ Sbjct: 62 MGPELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLVGE----VEQYTCDTLIIATGAT 117 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 AK + L EE + KG+SACA CDG ++NK +AV+GGG++A EEA FL+ V + Sbjct: 118 AKYLGLESEEKFMGKGVSACATCDGF--FYKNKDVAVVGGGNTAVEEALFLSNIAKSVTL 175 Query: 183 LVRKDHLRASTIM-QKRAEKNE--KIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDL 239 + R+D LR+ I+ K EK + I I++NT E GD +NALRIKN K NEE+ + Sbjct: 176 IHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQM 235 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSKYR 295 V+G+F AIGHTP T I AGQ++ E GYIK G ++ T++ G FAAGDV D Y+ Sbjct: 236 GVAGVFIAIGHTPNTSIFAGQLEM-ENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYK 294 Query: 296 QAITSAGSGCMAALDAEKYLTSLE 319 QA+TSAG+GCMAALDAEKYL +L+ Sbjct: 295 QAVTSAGTGCMAALDAEKYLDNLD 318 >1F6M-A nrPDB Length = 320 Score = 293 bits (749), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 160/324 (49%), Positives = 218/324 (67%), Gaps = 20/324 (6%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H+K+ I+GSGPA +TAA+Y ARA ++P+L GM GGQLTTTTE+EN+PG P+ L Sbjct: 5 HSKLLILGSGPAGYTAAVYAARANLQPVLITGM-----EKGGQLTTTTEVENWPGDPNDL 59 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 TG LM+RM E +TKF TEII + ++KVDL ++PF+L N D T DA+I+ATGAS Sbjct: 60 TGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRL----NGDNGEYTCDALIIATGAS 115 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 A+ + LP EE + +G+SA A CDG +RN+ +AVIGGG++A EEA +L+ S+V + Sbjct: 116 ARYLGLPSEEAFKGRGVSASATCDGF--FYRNQKVAVIGGGNTAVEEALYLSNIASEVHL 173 Query: 183 LVRKDHLRASTIMQKRAE---KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETD- 238 + R+D RA I+ KR +N I + N E GD + +R+++T+ ++ + Sbjct: 174 IHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIES 233 Query: 239 LPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSKY 294 L V+GLF AIGH+P T I GQ++ E GYIK G ++ TS+PG FAAGDV D Y Sbjct: 234 LDVAGLFVAIGHSPNTAIFEGQLEL-ENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHIY 292 Query: 295 RQAITSAGSGCMAALDAEKYLTSL 318 RQAITSAG+GCMAALDAE+YL L Sbjct: 293 RQAITSAGTGCMAALDAERYLDGL 316 >5UTH-A nrPDB Length = 319 Score = 293 bits (749), Expect = 9e-80, Method: Compositional matrix adjust. Identities = 153/314 (48%), Positives = 212/314 (67%), Gaps = 13/314 (4%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 VH+ V IIGSGPA +TAAIY ARA++KP+++EG GG L TTTE+EN+PGF +G Sbjct: 15 VHD-VIIIGSGPAGYTAAIYAARAQLKPLVFEGTQF-----GGALMTTTEVENYPGFREG 68 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 +TG ELMD+MREQ+ +FG ++ E V V L P K +E + A+ILA GA Sbjct: 69 ITGPELMDQMREQALRFGADLRMEDVDAVQLEG-PVKTVVVGDETHQA---RAVILAMGA 124 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 +A+ + +PGEE G+S CA CDG FR++ + V+GGGDSA EEA FLT++ V Sbjct: 125 AARHLGVPGEEALTGMGVSTCATCDGF--FFRDQDIVVVGGGDSAMEEATFLTRFARSVT 182 Query: 182 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 241 ++ R+D RAS IM +RA NEKI L NT + +GD K+ +R+++T EE+ L V Sbjct: 183 LIHRRDEFRASKIMLERARANEKITFLTNTEITQIEGDPKV-TGVRLRDTVTGEESKLDV 241 Query: 242 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 +G+F AIGH P +++V GQV+ D+ GY+K ++ TS+ G FAAGD+ D YRQAIT+A Sbjct: 242 TGVFVAIGHDPRSELVRGQVELDDEGYVKVQGRTTYTSLDGVFAAGDLVDHTYRQAITAA 301 Query: 302 GSGCMAALDAEKYL 315 GSGC A++DAE++L Sbjct: 302 GSGCAASIDAERWL 315 >5U63-A nrPDB Length = 321 Score = 292 bits (747), Expect = 1e-79, Method: Compositional matrix adjust. Identities = 163/326 (50%), Positives = 214/326 (65%), Gaps = 23/326 (7%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H K+ I+GSGPA +TAAIY ARA +KP+L G+ GGQLTTT EIEN+PG + Sbjct: 9 HAKLLILGSGPAGYTAAIYAARANLKPVL-----VTGLQQGGQLTTTDEIENWPGDFEMT 63 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 TGS LM RM + + KF TEI+ + +++VDLSS+PFKL+ D + T DA+I+ATGAS Sbjct: 64 TGSGLMQRMLQHAEKFETEIVFDHINRVDLSSRPFKLFG----DVQNFTCDALIIATGAS 119 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 A+ + LP EE Y +G+SACA CDG +RNKP+ VIGGG++A EEA +L S V + Sbjct: 120 ARYIGLPSEENYKGRGVSACATCDGF--FYRNKPVGVIGGGNTAVEEALYLANIASTVHL 177 Query: 183 LVRKDHLRASTIMQKRAEKNEKIE----ILYNTVAL-EAKGDGKLLNALRIKNTKKNEET 237 + R+D RA I+ R K K+E +L+ L E GD + LR+ NTK E+ Sbjct: 178 IHRRDSFRAEKILIDRLYK--KVEEGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKE 235 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSK 293 +L + GLF AIGH+P T+I GQ++ + GYI G ++ TSV G FAAGDV D Sbjct: 236 ELKLDGLFVAIGHSPNTEIFQGQLELNN-GYIVVKSGLDGNATATSVEGVFAAGDVMDHN 294 Query: 294 YRQAITSAGSGCMAALDAEKYLTSLE 319 YRQAITSAG+GCMAALDAE+YL + E Sbjct: 295 YRQAITSAGTGCMAALDAERYLDAQE 320 >5USX-A nrPDB Length = 319 Score = 287 bits (734), Expect = 5e-78, Method: Compositional matrix adjust. Identities = 156/325 (48%), Positives = 213/325 (65%), Gaps = 19/325 (5%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 M H+K+ I+GSGPA +TAA+Y ARA + P+L GM GGQLTTTTE+EN+PG P+ Sbjct: 4 MKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQ-----GGQLTTTTEVENWPGDPE 58 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 GLTG LMDRM+E + +F TEII + +++VD S++PF L DA + DA+I++TG Sbjct: 59 GLTGPGLMDRMKEHAERFETEIIFDHINEVDFSTRPFVL----KGDAASYSCDALIISTG 114 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ASAK + L EE + +G+SACA CDG +RN+ +AV+GGG++A EEA +L+ ++V Sbjct: 115 ASAKYLGLESEEAFKGRGVSACATCDGF--FYRNQKVAVVGGGNTAVEEALYLSNIAAEV 172 Query: 181 FMLVRKDHLRASTIMQKRAE---KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEET 237 ++ R+D RA I+ R +N I + + V E GD + +R+K+ K Sbjct: 173 HLIHRRDSFRAEKILINRLMDKVQNGNIVLHTDRVLDEVLGDEMGVTGVRLKDVKTGGTE 232 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSK 293 +L V G F AIGH+P T+I GQ+D + GYI G ++ TSV G FAAGDV D Sbjct: 233 ELDVMGAFIAIGHSPNTQIFQGQLDMKD-GYILVKSGLEGNATQTSVEGIFAAGDVMDHN 291 Query: 294 YRQAITSAGSGCMAALDAEKYLTSL 318 YRQAITSAG+GCMAALDAE+YL SL Sbjct: 292 YRQAITSAGTGCMAALDAERYLDSL 316 >2A87-A nrPDB Length = 335 Score = 286 bits (733), Expect = 6e-78, Method: Compositional matrix adjust. Identities = 145/312 (46%), Positives = 203/312 (65%), Gaps = 11/312 (3%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 V +IGSGPA +TAA+Y ARA++ P+++EG + GG L TTT++EN+PGF +G+T Sbjct: 15 RDVIVIGSGPAGYTAALYAARAQLAPLVFEG-----TSFGGALMTTTDVENYPGFRNGIT 69 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 G ELMD MREQ+ +FG ++ E V V L P K + D + A+ILA GA+A Sbjct: 70 GPELMDEMREQALRFGADLRMEDVESVSLHG-PLK--SVVTADGQTHRARAVILAMGAAA 126 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 + + +PGE+ +G+S+CA CDG FR++ +AVIGGGDSA EEA FLT++ V ++ Sbjct: 127 RYLQVPGEQELLGRGVSSCATCDGF--FFRDQDIAVIGGGDSAMEEATFLTRFARSVTLV 184 Query: 184 VRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 R+D RAS IM RA N+KI L N + GD + LR+++T ET LPV+G Sbjct: 185 HRRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGD-TTVTGLRVRDTNTGAETTLPVTG 243 Query: 244 LFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGS 303 +F AIGH P + +V +D D GY+ ++ TS+PG FAAGD+ D YRQA+T+AGS Sbjct: 244 VFVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGS 303 Query: 304 GCMAALDAEKYL 315 GC AA+DAE++L Sbjct: 304 GCAAAIDAERWL 315 >4JNQ-A nrPDB Length = 345 Score = 243 bits (621), Expect = 7e-65, Method: Compositional matrix adjust. Identities = 132/323 (40%), Positives = 196/323 (60%), Gaps = 16/323 (4%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H V +IGSGPA +TAAIY ARA +KP++ G+ GGQL TT++EN+PG+ + + Sbjct: 26 HAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQ-----GGQLMITTDVENYPGYAEPV 80 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 G +M++M Q+ G +I+ + +++V+ + +PF+L + T DA+I+ATGA Sbjct: 81 QGPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRL---KGDSGTIYTCDALIIATGAQ 137 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 AK + L E+T+ G+SACA CDG +R K + V+GGG++A EEA +L+ V + Sbjct: 138 AKWLGLESEQTFMGGGVSACATCDGF--FYRGKDVVVVGGGNTAVEEALYLSHIAKSVTI 195 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGD------GKLLNALRIKNTKKNEE 236 + R+D RA IMQ R E + +++N+V E G G + +R+KN E Sbjct: 196 VHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGET 255 Query: 237 TDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQ 296 + G+F AIGH PA + G++ GY+ T P S+ T VPG FAAGDV D YRQ Sbjct: 256 QERATHGVFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQ 315 Query: 297 AITSAGSGCMAALDAEKYLTSLE 319 A+T+AG GCMAAL+AE++L + E Sbjct: 316 AVTAAGMGCMAALEAERWLAAQE 338 >5M5J-A nrPDB Length = 325 Score = 241 bits (614), Expect = 4e-64, Method: Compositional matrix adjust. Identities = 144/320 (45%), Positives = 201/320 (62%), Gaps = 14/320 (4%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H ++ IIG GPA TA IY +RA +K ++ GI Q+ TTT++ENFP + Sbjct: 17 HVRIGIIGGGPAGLTAGIYASRANLKTCVF-----VGIEHTSQMFTTTDVENFPSHT-AI 70 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 G LM+ ++ Q+ G E++ E V +D+SS+PFK+ + E DA+I+ATGA+ Sbjct: 71 KGPALMEAIQNQAEHCGAELLYEDVHSIDVSSRPFKIVHGYEN--ETTLADALIIATGAT 128 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 A+R+ GE+ YWQKG+SACAVCD A+ K + V+GGGD ACEEA +LTK +KV+M Sbjct: 129 ARRLDCKGEKEYWQKGVSACAVCDSAMAT--GKEVVVVGGGDVACEEATYLTKIATKVYM 186 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS 242 ++R+D RAS M K+ + IEI+Y++ E KGDGK + ++ IKN K + L Sbjct: 187 VLRRDKFRASAAMVKKVMNEKLIEIIYDSAIDEIKGDGKCVTSVSIKNLKDGKTRTLNAG 246 Query: 243 GLFYAIGHTPATKIV-AGQVDTDEAGYI--KTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 L++A+GH P T + GQ++ DEAGYI K P + TSV G FAAGD D YRQA+ Sbjct: 247 ALYWAVGHDPQTSFLKKGQLEQDEAGYILLKDHP-TQRTSVDGVFAAGDCCDHLYRQAVV 305 Query: 300 SAGSGCMAALDAEKYLTSLE 319 +AGSG AALDAE++L E Sbjct: 306 AAGSGSKAALDAERWLAMQE 325 >5MJK-A nrPDB Length = 327 Score = 233 bits (594), Expect = 8e-62, Method: Compositional matrix adjust. Identities = 134/313 (42%), Positives = 191/313 (61%), Gaps = 13/313 (4%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V IIGSGPA TAA+Y AR+E+K +L E G+ GGQ+ T EIEN+PG+ + + G Sbjct: 27 VVIIGSGPAGMTAAMYTARSEMKTLLLE----RGVP-GGQMNNTAEIENYPGY-ETIMGP 80 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKR 125 EL +M E G E V+ ++ K+ TE +E T +II+ATGA+ ++ Sbjct: 81 ELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDE----FITKSIIIATGANHRK 136 Query: 126 MHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVR 185 + +PGEE Y +G+S CAVCDGA FRN+ + VIGGGDSA EEA +LT++G V ++ R Sbjct: 137 LEIPGEEEYGARGVSYCAVCDGA--FFRNQEILVIGGGDSAVEEALYLTRFGQSVTIMHR 194 Query: 186 KDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLF 245 +D LRA I+Q+RA K EKI ++++V +E KGD K + ++ KN K E T+ G+F Sbjct: 195 RDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAFGGIF 254 Query: 246 YAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGC 305 +G P + V+ TDEAG+I T T++PG FA GDV+ +RQ T+ G G Sbjct: 255 IYVGLDPVAEFVSDLGITDEAGWIIT-DDHMRTNIPGIFAVGDVRQKDFRQITTAVGDGA 313 Query: 306 MAALDAEKYLTSL 318 AA +A K++ L Sbjct: 314 QAAQEAYKFVVEL 326 >2Q7V-A nrPDB Length = 325 Score = 231 bits (588), Expect = 4e-61, Method: Compositional matrix adjust. Identities = 127/317 (40%), Positives = 187/317 (58%), Gaps = 15/317 (4%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V IIG GPA TAAIY RA++ ++ E M GGQ+ + E+ENFPGFP+ + G Sbjct: 11 VVIIGGGPAGLTAAIYTGRAQLSTLILEKGMP-----GGQIAWSEEVENFPGFPEPIAGM 65 Query: 66 ELMDRMREQSTKFGTEIITETVSKV--DLSSKPFKLWTE-FNEDAEPVTTDAIILATGAS 122 EL RM +Q+ KFG ++ + V V D +S P+ +N + A+ILATGA Sbjct: 66 ELAQRMHQQAEKFGAKVEMDEVQGVQHDATSHPYPFTVRGYNGEYR---AKAVILATGAD 122 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 +++ +PGE+ +W KG+S CA CDG ++ K + VIGGGD+A EE FLTK+ +V + Sbjct: 123 PRKLGIPGEDNFWGKGVSTCATCDGF--FYKGKKVVVIGGGDAAVEEGMFLTKFADEVTV 180 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS 242 + R+D LRA+ + Q RA N K++ +++T E +G ++ ++++N K E ++L Sbjct: 181 IHRRDTLRANKVAQARAFANPKMKFIWDTAVEEIQG-ADSVSGVKLRNLKTGEVSELATD 239 Query: 243 GLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAG 302 G+F IGH P T V V + GY+ V T++P FAAGDV D YRQ TS G Sbjct: 240 GVFIFIGHVPNTAFVKDTVSLRDDGYVD-VRDEIYTNIPMLFAAGDVSDYIYRQLATSVG 298 Query: 303 SGCMAALDAEKYLTSLE 319 +G AA+ E+ L +LE Sbjct: 299 AGTRAAMMTERQLAALE 315 >4GCM-A nrPDB Length = 312 Score = 211 bits (537), Expect = 4e-55, Method: Compositional matrix adjust. Identities = 130/314 (41%), Positives = 185/314 (58%), Gaps = 15/314 (4%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 + IIG+GPA TAA+Y +RA +K + M+ GI GGQ+ T E+ENFPGF + +TG Sbjct: 9 IAIIGAGPAGMTAAVYASRANLKTV----MIERGIP-GGQMANTEEVENFPGF-EMITGP 62 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKR 125 +L +M E + KFG + V+ + + N + +T A+I+ATGA K+ Sbjct: 63 DLSTKMFEHAKKFGAVYQYGDIKSVEDKGE----YKVINFGNKELTAKAVIIATGAEYKK 118 Query: 126 MHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVR 185 + +PGE+ +G+S CAVCDGA F+NK L VIGGGDSA EE FLTK+ KV ++ R Sbjct: 119 IGVPGEQELGGRGVSYCAVCDGA--FFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVHR 176 Query: 186 KDHLRASTIMQKRAEKNEKIEILY-NTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 +D LRA I+Q RA KN+KI+ ++ +T+ + DGK + ++ + +TK E G+ Sbjct: 177 RDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGK-VGSVTLTSTKDGSEETHEADGV 235 Query: 245 FYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 F IG P T T++ GYI T TSVPG FAAGDV+D RQ +T+ G G Sbjct: 236 FIYIGMKPLTAPFKDLGITNDVGYIVT-KDDMTTSVPGIFAAGDVRDKGLRQIVTATGDG 294 Query: 305 CMAALDAEKYLTSL 318 +AA A +Y+ L Sbjct: 295 SIAAQSAAEYIEHL 308 >5UWY-A nrPDB Length = 308 Score = 207 bits (527), Expect = 5e-54, Method: Compositional matrix adjust. Identities = 125/312 (40%), Positives = 180/312 (57%), Gaps = 15/312 (4%) Query: 8 IIGSGPAAHTAAIYLARAEIK-PILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSE 66 IIGSGPA TAA+Y AR+ + I+ +G A GGQ+ T +IEN+PG+ D ++G E Sbjct: 9 IIGSGPAGMTAALYAARSNLSVAIIEQG------APGGQMNNTFDIENYPGY-DHISGPE 61 Query: 67 LMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRM 126 L +M E KF E I V K++ + +K EDA +I+ATGA + + Sbjct: 62 LAMKMYEPLEKFNVENIYGIVQKIE-NFGDYK--CVLTEDAS-YEAKTVIIATGAKYRVL 117 Query: 127 HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRK 186 +PGEE Y +G+S CAVCDGA FR++ L V+GGGDSA EEA +LT++ KV ++ R+ Sbjct: 118 GVPGEEYYTSRGVSYCAVCDGA--FFRDQDLLVVGGGDSAVEEAIYLTQFAKKVTVVHRR 175 Query: 187 DHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFY 246 D LRA I+Q RA N+K++ ++++V E +G+ ++ + I+N K + TD G+F Sbjct: 176 DQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGVFI 235 Query: 247 AIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCM 306 +G P T +V TD G+I T TS+PG FA GDV+ RQ T+ G G + Sbjct: 236 YVGMNPVTGMVKDLEITDSEGWIIT-DDHMRTSIPGIFAIGDVRQKDLRQITTAVGDGAI 294 Query: 307 AALDAEKYLTSL 318 A YL S Sbjct: 295 AGQGVYHYLESF 306 >3ISH-A nrPDB Length = 311 Score = 194 bits (492), Expect = 6e-50, Method: Compositional matrix adjust. Identities = 117/314 (37%), Positives = 173/314 (55%), Gaps = 17/314 (5%) Query: 8 IIGSGPAAHTAAIYLARAEIK-PILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSE 66 IIG GPA +A +Y R +K +L+E M GGQ+T ++EIEN+PG + ++G + Sbjct: 6 IIGGGPAGLSAGLYATRGGVKNAVLFEKGMP-----GGQITGSSEIENYPGVKEVVSGLD 60 Query: 67 LMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRM 126 M +EQ +FG + V +V F + E D + ++I+ATG S KR Sbjct: 61 FMQPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILAE---DGKTFEAKSVIIATGGSPKRT 117 Query: 127 HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRK 186 + GE YW KG+S CA CDG ++NK +AV+GGGD+A EEA +L KV+++ R+ Sbjct: 118 GIKGESEYWGKGVSTCATCDGF--FYKNKEVAVLGGGDTAVEEAIYLANICKKVYLIHRR 175 Query: 187 DHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFY 246 D R + I + A+ N+KIE L V E KGD +++L IKNT NE+ +L V G F Sbjct: 176 DGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNEKRELVVPGFFI 235 Query: 247 AIGHTPATKIVAGQVDT-----DEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 +G+ ++ + ++ DE G I V S T+V G FAAGD++ +Q + +A Sbjct: 236 FVGYDVNNAVLKQEDNSMLCKCDEYGSI-VVDFSMKTNVQGLFAAGDIRIFAPKQVVCAA 294 Query: 302 GSGCMAALDAEKYL 315 G AAL YL Sbjct: 295 SDGATAALSVISYL 308 >4ZN0-A nrPDB Length = 311 Score = 187 bits (475), Expect = 5e-48, Method: Compositional matrix adjust. Identities = 115/317 (36%), Positives = 180/317 (56%), Gaps = 20/317 (6%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 + IIG GPA TA IY R + ++ E N I+ GQ++ +EN+PGFP ++G Sbjct: 10 LIIIGGGPAGLTAGIYAVRYGLDTLILE---RNEIS--GQISMADIVENYPGFPS-ISGL 63 Query: 66 ELMDRMREQSTKFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 ELM+R R + + G + ITE +S +K D+ + A+I+ATGA+ K Sbjct: 64 ELMERFRTHAQEVGVKTTITEVLSVRSEGTKKI-----ITTDSGDLEAKAVIIATGANPK 118 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + +PGE+ KG+S CA+CDG P FRNK +AV+GGG+SA +A FL+K KV+++ Sbjct: 119 HLGVPGEKELISKGVSYCAICDG--PFFRNKIVAVVGGGNSAVTDALFLSKVAQKVYLVH 176 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDG---KLLNALRIKNTKKNEETDLPV 241 R+DHL+A+ ++Q R + IE++ N+ LE G K + + +++ E +L Sbjct: 177 RRDHLKAARVLQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELST 236 Query: 242 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 +G+F +G P T+ V V+ DE G+IKT TS G +AAGD +D+ Q +T+ Sbjct: 237 NGVFIYVGIHPNTEFV--DVEKDEGGFIKTDRWME-TSEKGIYAAGDCRDTPIWQLVTAV 293 Query: 302 GSGCMAALDAEKYLTSL 318 G +AA A +Y+ + Sbjct: 294 RDGAIAATAAYEYIEKI 310 >3F8P-A nrPDB Length = 323 Score = 179 bits (455), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 109/314 (34%), Positives = 178/314 (56%), Gaps = 17/314 (5%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I+G GPAA+ AA+Y AR +K ++ G GGQLT ++++ G + + S Sbjct: 18 VIIVGLGPAAYGAALYSARYMLKTLVI------GETPGGQLTEAGIVDDYLGLIE-IQAS 70 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKR 125 +++ + K+ ++ + V K++ F + T+ + + D++IL G ++ Sbjct: 71 DMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGEFK---ADSVILGIGVKRRK 127 Query: 126 MHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVR 185 + +PGE+ + +GIS C+VCD P+F+N+ +AVIGGGDSA E A+ L+ Y +KV+++ R Sbjct: 128 LGVPGEQEFAGRGISYCSVCDA--PLFKNRVVAVIGGGDSALEGAEILSSYSTKVYLIHR 185 Query: 186 KDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLF 245 +D +A I + +K +E + N+V E KGD K++ + ++N K E +L V+G+F Sbjct: 186 RDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGD-KVVKQVVVENLKTGEIKELNVNGVF 244 Query: 246 YAIGHTPATKIVAGQ-VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDS--KYRQAITSAG 302 IG P T ++TD GYIK V TSVPG FAAGD + +RQ IT+ Sbjct: 245 IEIGFDPPTDFAKSNGIETDTNGYIK-VDEWMRTSVPGVFAAGDCTSAWLGFRQVITAVA 303 Query: 303 SGCMAALDAEKYLT 316 G +AA A +Y+T Sbjct: 304 QGAVAATSAYRYVT 317 >3R9U-A nrPDB Length = 315 Score = 170 bits (431), Expect = 7e-43, Method: Compositional matrix adjust. Identities = 111/321 (34%), Positives = 173/321 (53%), Gaps = 21/321 (6%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V IIG GPA +A +Y R +K ++ M G+ GGQ+T+++EIEN+PG + G Sbjct: 7 VAIIGGGPAGLSAGLYATRGGLKNVV---MFEKGMP-GGQITSSSEIENYPGVAQVMDGI 62 Query: 66 ELMDRMREQSTKFGTE---IITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 M EQ +FG + + E + K S KL E + A+I+ TG++ Sbjct: 63 SFMAPWSEQCMRFGLKHEMVGVEQILKNSDGSFTIKL-----EGGKTELAKAVIVCTGSA 117 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 K+ GE+ ++ KG+S CA CDG ++NK +AV+GGGD+A EEA +L SK+++ Sbjct: 118 PKKAGFKGEDEFFGKGVSTCATCDGF--FYKNKEVAVLGGGDTALEEALYLANICSKIYL 175 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS 242 + R+D RA+ ++ +KNEKIE++ + E GD + +++K K DL V Sbjct: 176 IHRRDEFRAAPSTVEKVKKNEKIELITSASVDEVYGDKMGVAGVKVK-LKDGSIRDLNVP 234 Query: 243 GLFYAIGHTPATKIVAGQ-----VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQA 297 G+F +G +I+ + +E G + +V TSV G FAAGD++ +Q Sbjct: 235 GIFTFVGLNVRNEILKQDDSKFLCNMEEGGQV-SVDLKMQTSVAGLFAAGDLRKDAPKQV 293 Query: 298 ITSAGSGCMAALDAEKYLTSL 318 I +AG G +AAL A Y+ SL Sbjct: 294 ICAAGDGAVAALSAMAYIESL 314 >1FL2-A nrPDB Length = 310 Score = 134 bits (336), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 101/311 (32%), Positives = 160/311 (51%), Gaps = 11/311 (3%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I+GSGPA AAIY AR I+ G+M G GGQ+ T +IEN+ P G Sbjct: 4 VLIVGSGPAGAAAAIYSARKGIRT----GLM--GERFGGQILDTVDIENYISVPK-TEGQ 56 Query: 66 ELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 +L ++ ++ ++I +++ SK+ ++ L + +II+ATGA + Sbjct: 57 KLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWR 116 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 M++PGE+ Y KG++ C CDG P+F+ K +AVIGGG+S E A L V +L Sbjct: 117 NMNVPGEDQYRTKGVTYCPHCDG--PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 174 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 ++A ++Q + + ++I+ N E KGDG + L ++ + ++ ++G+ Sbjct: 175 FAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGI 234 Query: 245 FYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 F IG P T + G V+ + G I + T+V G FAAGD Y+Q I + G G Sbjct: 235 FVQIGLLPNTNWLEGAVERNRMGEI-IIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEG 293 Query: 305 CMAALDAEKYL 315 A+L A YL Sbjct: 294 AKASLSAFDYL 304 >4YKF-A nrPDB Length = 521 Score = 133 bits (335), Expect = 1e-31, Method: Compositional matrix adjust. Identities = 101/311 (32%), Positives = 160/311 (51%), Gaps = 11/311 (3%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I+GSGPA AAIY AR I+ G+M G GGQ+ T +IEN+ P G Sbjct: 215 VLIVGSGPAGAAAAIYSARKGIRT----GLM--GERFGGQILDTVDIENYISVPK-TEGQ 267 Query: 66 ELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 +L ++ ++ ++I +++ SK+ ++ L + +II+ATGA + Sbjct: 268 KLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKWR 327 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 M++PGE+ Y KG++ C CDG P+F+ K +AVIGGG+S E A L V +L Sbjct: 328 NMNVPGEDQYRTKGVTYCPHCDG--PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 385 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 ++A ++Q + + ++I+ N E KGDG + L ++ + ++ ++G+ Sbjct: 386 FAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAGI 445 Query: 245 FYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 F IG P T + G V+ + G I + T+V G FAAGD Y+Q I + G G Sbjct: 446 FVQIGLLPNTNWLEGAVERNRMGEI-IIDAKCETNVKGVFAAGDCTTVPYKQIIIATGEG 504 Query: 305 CMAALDAEKYL 315 A+L A YL Sbjct: 505 AKASLSAFDYL 515 >3LZX-A nrPDB Length = 332 Score = 66.6 bits (161), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 82/308 (26%), Positives = 139/308 (45%), Gaps = 25/308 (8%) Query: 6 VTIIGSGPAAHTAAIY--LARAEIKPILYEGMMANGIAAGGQLTTT---TEIENFPGFPD 60 +TIIG GP A Y + +A +K ++ + GGQL+ I + GFP Sbjct: 10 ITIIGGGPVGLFTAFYGGMRQASVK------IIESLPQLGGQLSALYPEKYIYDVAGFPK 63 Query: 61 GLTGSELMDRMREQSTKFGTEIITE-TVSKVDLSSK-PFKLWTEFNEDAEPVTTDAIILA 118 + EL++ ++EQ KF I E V V+ + FKL T NE+ T I Sbjct: 64 -IRAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVT--NEETHYSKTVIITAG 120 Query: 119 TGA-SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 GA +++ L E Y K + V D + F + +A++GGGDSA + A L Sbjct: 121 NGAFKPRKLELENAEQYEGKNLHYF-VDD--LQKFAGRRVAILGGGDSAVDWALMLEPIA 177 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEET 237 +V ++ R+D RA + + K+ +L V E G+ K + L ++ K + + Sbjct: 178 KEVSIIHRRDKFRAHEHSVENLHAS-KVNVLTPFVPAELIGEDK-IEQLVLEEVKGDRKE 235 Query: 238 DLPVSGLFYAIGHTPATKIVAGQ-VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQ 296 L + L G + + +D ++ + V + T++ GFFAAGD+ + + Sbjct: 236 ILEIDDLIVNYGFVSSLGPIKNWGLDIEKNSIV--VKSTMETNIEGFFAAGDICTYEGKV 293 Query: 297 AITSAGSG 304 + ++G G Sbjct: 294 NLIASGFG 301 >2ZBW-A nrPDB Length = 335 Score = 65.5 bits (158), Expect = 3e-11, Method: Compositional matrix adjust. Identities = 74/297 (24%), Positives = 123/297 (41%), Gaps = 23/297 (7%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE---IENFPGFP 59 H V I+G+GP A Y+ + + + GGQLT I + GFP Sbjct: 5 HTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPE----PGGQLTALYPEKYIYDVAGFP 60 Query: 60 DGLTGSELMDRMREQSTKFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 + +L+ + EQ F + E ++ FK+ T T A+I+A Sbjct: 61 K-VYAKDLVKGLVEQVAPFNPVYSLGERAETLEREGDLFKVTTS---QGNAYTAKAVIIA 116 Query: 119 TGASA---KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTK 175 G A +R+ PGE + +G+ F+ K + ++GGGDSA + A L Sbjct: 117 AGVGAFEPRRIGAPGEREFEGRGVYYAVKSKAE---FQGKRVLIVGGGDSAVDWALNLLD 173 Query: 176 YGSKVFMLVRKDHLRASTIMQK---RAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTK 232 ++ ++ R+ RA K +A + ++E+L +GD ++ A+ N + Sbjct: 174 TARRITLIHRRPQFRAHEASVKELMKAHEEGRLEVLTPYELRRVEGDERVRWAVVFHN-Q 232 Query: 233 KNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDV 289 EE L V + G+ +A E IK V + TS+PG +A GD+ Sbjct: 233 TQEELALEVDAVLILAGYITKLGPLANWGLALEKNKIK-VDTTMATSIPGVYACGDI 288 >5YGQ-A nrPDB Length = 342 Score = 64.3 bits (155), Expect = 7e-11, Method: Compositional matrix adjust. Identities = 88/328 (26%), Positives = 138/328 (42%), Gaps = 28/328 (8%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 + V I+G+GP A L ++K L + + G +L I + PG P Sbjct: 5 IKTDVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVG-GQCAELYPEKPIYDIPGIP-M 62 Query: 62 LTGSELMDRMREQSTKFG-TEIITETVSKVDLSSKP-FKLWTEFNEDAEPVTTDAIILAT 119 +TG L + + EQ F T ++E V V+ P F++ T + E T ++ A Sbjct: 63 VTGHGLTEALMEQIKPFNPTFHLSEMVENVEKIGDPGFRVTTNAGKVFE--CTVLVVAAG 120 Query: 120 GAS--AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 G S KR +PG E Y +G S + FR K + ++GGGDSA + L Sbjct: 121 GGSFLPKRPPVPGVEAY--EGTSVHYAVR-KMEDFRGKDILIVGGGDSALDWTLNLNPIA 177 Query: 178 SKVFMLVRKDHLRA---STIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIK---NT 231 + ++ R+D R S ++ + K+++ + E +GD L +K NT Sbjct: 178 KSMTLVHRRDDFRGAPHSVEQMRQLVASGKLDLKIGQIT-ELQGDNGQLTGATVKLNDNT 236 Query: 232 KKNEETD--LPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDV 289 + D LP GL +G VA E I G+ T+VPG FA GD+ Sbjct: 237 TSQIKCDAMLPFFGLTMKLGP------VANWGLDLENNLIPVDTGTFETNVPGIFAIGDI 290 Query: 290 Q--DSKYRQAITSAGSGCMAALDAEKYL 315 K + ++ G + A A KY+ Sbjct: 291 NTYPGKLKLILSGFHEGALMAQKAVKYV 318 >6GAS-A nrPDB Length = 331 Score = 61.2 bits (147), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 82/317 (25%), Positives = 136/317 (42%), Gaps = 43/317 (13%) Query: 6 VTIIGSGPAAHTAAIY--LARAEIKPILYEGMMANGIAAGGQLTTT---TEIENFPGFPD 60 +TIIG GP A Y + +A +K ++ + GGQL+ I + GFP Sbjct: 12 ITIIGGGPTGLFTAFYGGMRQASVK------IIESLPQLGGQLSALYPEKYIYDVAGFPK 65 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKP----FKLWTEFNEDAEPVTTDAII 116 + EL+D ++EQ KF + E VD K FKL T + + + ++I Sbjct: 66 -VRAQELVDNLKEQMKKFDPTVCLEEA--VDTLEKQADGIFKLVT----NKQTHYSKSVI 118 Query: 117 LATGASA---KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFL 173 + G A +R+ L G Y +K + + F K + V GGGDSA + L Sbjct: 119 ITAGNGAFQPRRLELEGTAKYEKKNLHYFV---DDMNKFAGKRVVVFGGGDSAVDWTMML 175 Query: 174 TKYGSKVFMLVRKDHLRA-----STIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRI 228 KV ++ R+D RA +M RAE + Y V +E GD K+ + + Sbjct: 176 EPIAEKVTIVHRRDKFRAHEHSVENLMNSRAE----VSTPY--VPVELIGDDKIEQVV-L 228 Query: 229 KNTKKNEETDLPVSGLFYAIGHTPATKIVAGQ-VDTDEAGYIKTVPGSSLTSVPGFFAAG 287 ++ K E+ + V + G + + +D + + V T++PG +AAG Sbjct: 229 QHVKTEEKVIIDVDDVIVNYGFVSSLGPIKNWGLDIQKNSIL--VNSKMETNIPGIYAAG 286 Query: 288 DVQDSKYRQAITSAGSG 304 D+ + + + + G G Sbjct: 287 DICTYEGKVKLIACGFG 303 >4YRY-B nrPDB Length = 468 Score = 60.1 bits (144), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 91/347 (26%), Positives = 146/347 (42%), Gaps = 63/347 (18%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV ++GSGPA TAA LA+ ++E GG L G P+ Sbjct: 142 KVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHK----PGGVLVY--------GIPEFRLP 189 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA-SA 123 +++R K G TV V + K +L +E+ DA+ + TGA + Sbjct: 190 KRIVEREVSYIRKLGVNFHLNTV--VGKTVKVKELLSEY---------DAVFIGTGAGTP 238 Query: 124 KRMHLPG----------EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFL 173 K M +PG E + A + PI K +AVIG G++A + A+ Sbjct: 239 KFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAARSA 298 Query: 174 TKYGS-KVFMLVRKDHLRASTIMQKRAEK-----NEKIEILYNTVAL----EAKGDGKLL 223 + G+ KV+++ R R M R E+ E IE L+ T+ + +A G+ + + Sbjct: 299 LRLGAEKVYIVYR----RTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAM 354 Query: 224 NALRIKNTKKN---EETDLPVSG---------LFYAIGHTPATKIVA--GQVDTDEAGYI 269 +R++ + + +P+ G + AIG P +++ ++ +E GYI Sbjct: 355 ECVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYI 414 Query: 270 KTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLT 316 K + TSV G FA GD+ I + G+G AA YLT Sbjct: 415 KADEDTGATSVKGVFAGGDIVTGA-ATVIKAMGAGKKAAQFIHSYLT 460 >6GAR-A nrPDB Length = 349 Score = 57.0 bits (136), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 71/296 (23%), Positives = 133/296 (44%), Gaps = 25/296 (8%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE--IENFPGFPDGLT 63 VT+IG GPA +A Y E++ + E GG++ E I + G +T Sbjct: 9 VTVIGGGPAGLYSAFYSGLREMRTKIIEFHPH----LGGKIHVYPEKMIWDVGGLLP-VT 63 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKP--FKLWTEFNEDAEPVTTDAIILATGA 121 G +L++++ +Q F E++ +T + + ++ F L T E+ + +I+ATG+ Sbjct: 64 GDKLIEQLVQQGLTFKPEVVLDTKVESIIRNQDGTFTLKTSTGEEH---FSKTVIVATGS 120 Query: 122 ---SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGS 178 +++ + G E + +S ++ F+ K + + GGG+SA + A L Sbjct: 121 GILKPQKLSIEGAERF---EVSNLNYTVKSLKRFKGKTVIISGGGNSAVDWANELEPIAK 177 Query: 179 KVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT--VALEAKGDGKLLNALRIKNTKKNEE 236 KV++ RK+ L Q + N E +NT L A + + + + + N + E Sbjct: 178 KVYVTYRKEELSGHE-AQVKQLMNSSAECFFNTSITKLIAGDNHEAIEYVELTNHETGEV 236 Query: 237 TDLPVSGLFYAIGHTPATKIVAGQVDTDEA---GYIKTVPGSSLTSVPGFFAAGDV 289 + LP+ + G+ ++ + D A Y +S +SV G +AAGD+ Sbjct: 237 SHLPIDEVIINHGYERDITLLENS-ELDVAIIDNYYIAGNANSESSVDGLYAAGDI 291 >5JFC-L nrPDB Length = 474 Score = 55.8 bits (133), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 86/342 (25%), Positives = 140/342 (40%), Gaps = 54/342 (15%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV IIG+GPA T A LA+ + +YE + GG L G P+ Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQ----PGGVLIY--------GIPEFRLP 203 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 E++ + E + G +I T + ++ + E E+ DAI + TGA Sbjct: 204 KEIVKKELENLRRLGVKIETNVLVGKTIT------FEELREE-----YDAIFIGTGAGTP 252 Query: 125 RMH-LPG----------EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFL 173 R++ PG E + A + PI K +AVIGGG++A + A+ Sbjct: 253 RIYPWPGVNLNGIYSANEFLTRINLMKAYKFPEYDTPIKVGKRVAVIGGGNTAMDAARSA 312 Query: 174 TKYGSKVFMLVRKDHLRAST-IMQKRAEKNEKIEILYNTVALEAKGD-GKLLNALRIKNT 231 + G++V++L R+ + + + + E ++ ++ GD L A+ ++ Sbjct: 313 LRLGAEVWILYRRTRKEMTAREEEIKHAEEEGVKFMFLVTPKRFIGDENGNLKAIELEKM 372 Query: 232 KKNEETD------LPVSGLF--------YAIGHTPATKIV--AGQVDTDEAGYIKTVPGS 275 K E + +P F AIG TP + + DE G I V + Sbjct: 373 KLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQTPNKTFLETVPGLKVDEWGRI-VVDEN 431 Query: 276 SLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTS 317 +TS+PG FA GD + I + G G AA +YL+ Sbjct: 432 LMTSIPGVFAGGDAIRGEA-TVILAMGDGRKAAKAIHQYLSK 472 >5VDN-A nrPDB Length = 463 Score = 53.5 bits (127), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 58/194 (29%), Positives = 88/194 (45%), Gaps = 27/194 (13%) Query: 106 DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGD 164 + E +T D I++ATG +PG E GI + DG + K +AV+G G Sbjct: 139 NGETITADHILIATGGRPSHPDIPGAE----YGIDS----DGFFELDEMPKRVAVVGAGY 190 Query: 165 SACEEAQFLTKYGSKVFMLVRK-------DHLRASTIMQKRAEKNEKIEILYNTVALEAK 217 A E A L G++ + VRK D L T+++ + K+ A+ Sbjct: 191 IAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLHTESVPKAVIKN 250 Query: 218 GDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKTVPG 274 DG L L+++N T++ V L +AIG PAT + V T++ GYI+ V Sbjct: 251 ADGSL--TLQLENG-----TEVTVDHLIWAIGREPATDNLNLSVTGVKTNDKGYIE-VDK 302 Query: 275 SSLTSVPGFFAAGD 288 T+V G +A GD Sbjct: 303 FQNTNVKGIYAVGD 316 >2CVJ-A nrPDB Length = 180 Score = 52.4 bits (124), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 27/97 (27%), Positives = 52/97 (53%), Gaps = 7/97 (7%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V ++G GP+ +AA++LARA +K ++ +G + ++ + + N+PG D +G Sbjct: 4 VIVVGGGPSGLSAALFLARAGLKVLVLDGGRS-------KVKGVSRVPNYPGLLDEPSGE 56 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTE 102 EL+ R+ + ++G E+ V V F++ TE Sbjct: 57 ELLRRLEAHARRYGAEVRPGVVKGVRDMGGVFEVETE 93 >1ZK7-A nrPDB Length = 467 Score = 52.0 bits (123), Expect = 4e-07, Method: Compositional matrix adjust. Identities = 67/207 (32%), Positives = 88/207 (42%), Gaps = 33/207 (15%) Query: 99 LWTEFNEDAEPVTT-DAIILATGASAKRMHLPG--EETYWQKGISACAVCDGAVPIFRNK 155 L NE E V D ++ATGAS +PG E YW S A+ +P + Sbjct: 125 LTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYW---TSTEALASDTIP----E 177 Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD-HLRASTIMQK---RAEKNEKIEILYNT 211 LAVIG A E AQ + GSKV +L R R + + A + E IE+L +T Sbjct: 178 RLAVIGSSVVALELAQAFARLGSKVTVLARNTLFFREDPAIGEAVTAAFRAEGIEVLEHT 237 Query: 212 VALE-AKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIK 270 A + A DG+ + T E L L A G TP T+ +A D AG Sbjct: 238 QASQVAHMDGEF-----VLTTTHGE---LRADKLLVATGRTPNTRSLA----LDAAGVTV 285 Query: 271 TVPGSSL------TSVPGFFAAGDVQD 291 G+ + TS P +AAGD D Sbjct: 286 NAQGAIVIDQGMRTSNPNIYAAGDCTD 312 >5VJ7-A nrPDB Length = 476 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 86/344 (25%), Positives = 147/344 (42%), Gaps = 57/344 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV IIG+GPA T A LA+ + +YE + GG LT G P+ Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYEALH----QPGGVLTY--------GIPEFRLP 203 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 E++ + ++ + G EI T+ + ++ + +L E+ DA+ + TGA Sbjct: 204 KEILRKELKKLSLLGVEIKTDHIVGKTITIQ--ELLQEY---------DAVFIGTGAGTP 252 Query: 125 RM-HLPG----------EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFL 173 ++ ++PG E + A + PI K + VIG G++A + A+ Sbjct: 253 KLPNIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKKVVVIGAGNTAMDAARSA 312 Query: 174 TKYGSKVFMLVR--KDHLRASTIMQKRAEKNEKIEILYNTVALEAKGD-GKLLNALRIKN 230 + G++V + R ++ + A K AE+ E ++ ++ +E GD + A++ + Sbjct: 313 LRLGAEVTIAYRRGREDMTARIEEVKHAEE-EGVKFMFFVNPVEFIGDENGNVKAVKFEK 371 Query: 231 TKKNEETD---------------LPVSGLFYAIGHTPATKI--VAGQVDTDEAGYIKTVP 273 K EE D + + AIG TP + ++ DE G I V Sbjct: 372 MKPLEERDSRGKRKIVGTGEYITVEADTVIIAIGQTPNKVLWRATPELKVDEWGRI-VVD 430 Query: 274 GSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTS 317 + +TS+PG FA GD + I + G G AA +YL+ Sbjct: 431 ENLMTSIPGVFAGGDAIRGEA-TVILAMGDGRKAAKAIHQYLSK 473 >5U1O-A nrPDB Length = 458 Score = 47.4 bits (111), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 54/196 (27%), Positives = 85/196 (43%), Gaps = 25/196 (12%) Query: 106 DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 + E T D I++A G ++PG E GI + D A + K +AV+G G Sbjct: 133 NGEHYTADHILIAVGGRPTIPNIPGAEY----GIDSNGFFDLAE---QPKRVAVVGAGYI 185 Query: 166 ACEEAQFLTKYGSKVFMLVRK-------DHLRASTIMQKRAEKNEKIEILYNTVALEAKG 218 A E A L G++ + VRK D + T+++ + + + + Sbjct: 186 AVEIAGVLHALGTETHLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLHTHSVPKEVVKEA 245 Query: 219 DGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKTVPGS 275 DG L L ++N + V L +AIG PAT + + V T+E GYIK V Sbjct: 246 DGSL--TLHLENGESQN-----VDQLIWAIGRHPATDAINLASTGVATNEKGYIK-VDEY 297 Query: 276 SLTSVPGFFAAGDVQD 291 T+V G + GD+ + Sbjct: 298 QETNVKGIYCVGDIME 313 >5XHU-A nrPDB Length = 329 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 72/326 (22%), Positives = 133/326 (40%), Gaps = 35/326 (10%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE---IENFPGFPDGL 62 VTIIG GP A Y E+K + E + GG+++ I + G P G+ Sbjct: 5 VTIIGGGPIGLFTAFYCGMRELKTKVIEFLPK----LGGKVSLFFPEKIIRDIGGIP-GI 59 Query: 63 TGSELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 G +L+++++EQ+ F +I+ + V+ + + T + + T +ILA G Sbjct: 60 AGKQLIEQLKEQAATFDPDIVLNQRVTGFERLDDGTIVLT--GSEGKKHYTRTVILACGM 117 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 ++ E + + F+ K + + GGGD+A + A L + V Sbjct: 118 GTLEVNEFDSEDAARYAGKNLHYGVEKLDAFKGKRVVISGGGDTAVDWANELEPIAASVT 177 Query: 182 MLVRKDHL--RASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDL 239 ++ R++ S++ + K + +L + GD + + ++ + +T+ + D+ Sbjct: 178 VVHRREEFGGMESSVTKM---KQSSVRVLTPYRLEQLNGDEEGIKSVTVCHTESGQRKDI 234 Query: 240 PVSGLF----YAIGHTP----ATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGD--V 289 + L + I P +I G+V D T++PG F AGD Sbjct: 235 EIDELIINHGFKIDLGPMMEWGLEIEEGRVKADR---------HMRTNLPGVFVAGDAAF 285 Query: 290 QDSKYRQAITSAGSGCMAALDAEKYL 315 +SK R G A A+ YL Sbjct: 286 YESKLRLIAGGFTEGPTAVNSAKAYL 311 >3AB1-A nrPDB Length = 360 Score = 45.8 bits (107), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 71/302 (23%), Positives = 126/302 (41%), Gaps = 37/302 (12%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTT---TEIENFPGFPDGL 62 +TIIG GP AA I + E M GGQL I + GFP+ + Sbjct: 17 LTIIGGGPTGIFAAFQCGMNNISCRIIESMPQ----LGGQLAALYPEKHIYDVAGFPE-V 71 Query: 63 TGSELMDRMREQSTKFGTEII-TETVSK-VDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 +L++ + Q+ ++ +++ ETV+K L F+ T + A+++A G Sbjct: 72 PAIDLVESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTN---TGNVYRSRAVLIAAG 128 Query: 121 ASA---KRM-------HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEA 170 A +++ HL G Y+ + +V D F+ K + ++GGGDSA + Sbjct: 129 LGAFEPRKLPQLGNIDHLTGSSVYY----AVKSVED-----FKGKRVVIVGGGDSALDWT 179 Query: 171 QFLTKYGSKVFMLVRKDHLRA---STIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALR 227 L K + V ++ R + + +RA N I++ T + +L + Sbjct: 180 VGLIKNAASVTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVH 239 Query: 228 IKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAG 287 ++++ ++ T + L IG +A + D + V TSV G +AAG Sbjct: 240 LRSSDGSKWT-VEADRLLILIGFKSNLGPLA-RWDLELYENALVVDSHMKTSVDGLYAAG 297 Query: 288 DV 289 D+ Sbjct: 298 DI 299 >3CGD-A nrPDB Length = 480 Score = 45.1 bits (105), Expect = 4e-05, Method: Compositional matrix adjust. Identities = 62/226 (27%), Positives = 97/226 (42%), Gaps = 26/226 (11%) Query: 77 KFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYW 135 K+G + + V+KVD K +D + D +++ATG R +P E Sbjct: 105 KYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLIATGV---RPVMPEWEGRD 161 Query: 136 QKGISACAVCDGAVPIFR----NK--PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 +G+ A I + NK + +IGGG E A+ + G KV M+ R DH+ Sbjct: 162 LQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAETFVELGKKVRMIERNDHI 221 Query: 190 ------RASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 + + K A+K+ IEIL N KG+ ++ K T K DL Sbjct: 222 GTIYDGDMAEYIYKEADKHH-IEILTNENVKAFKGNERVEAVETDKGTYK---ADL---- 273 Query: 244 LFYAIGHTPATKIVAG-QVDTDEAGYIKTVPGSSLTSVPGFFAAGD 288 + ++G P T + G + T+ G I+ V T+V +AAGD Sbjct: 274 VLVSVGVKPNTDFLEGTNIRTNHKGAIE-VNAYMQTNVQDVYAAGD 318 >5V36-A nrPDB Length = 453 Score = 45.1 bits (105), Expect = 5e-05, Method: Compositional matrix adjust. Identities = 59/198 (29%), Positives = 83/198 (41%), Gaps = 35/198 (17%) Query: 108 EPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCD-GAVPIFRNKPLAVIGGGDSA 166 E T I++ATG A +PG E GI++ + A+P K AV+G G A Sbjct: 131 EHYTAPHILIATGGHALLPDIPGSE----YGITSDGFFELDAIP----KRTAVVGAGYIA 182 Query: 167 CEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNAL 226 E + L GS+ + VR+D R + EI+ T+ E K DG L+ Sbjct: 183 VEISGILHALGSETHLFVRRD----------RPLRKFDKEIV-GTLVDEMKKDGPHLHTF 231 Query: 227 RI-KNTKKNEETDL----------PVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTV 272 + K KN + L V L +AIG TK + V D G+I T Sbjct: 232 SVPKEVIKNTDNSLTLILENGEEYTVDTLIWAIGRAANTKGFNLEVTGVTLDSRGFIATD 291 Query: 273 PGSSLTSVPGFFAAGDVQ 290 + T+V G +A GDV Sbjct: 292 AFEN-TNVEGLYALGDVN 308 >2R9Z-A nrPDB Length = 463 Score = 44.3 bits (103), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 50/195 (25%), Positives = 88/195 (45%), Gaps = 27/195 (13%) Query: 106 DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGD 164 + + ++ D I++ATG LPG E GI++ DG + + K +A+IG G Sbjct: 125 EGQRLSADHIVIATGGRPIVPRLPGAEL----GITS----DGFFALQQQPKRVAIIGAGY 176 Query: 165 SACEEAQFLTKYGSKVF-------MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAK 217 E A L +GS+V +L + D L ++T+ + + + + + ALE Sbjct: 177 IGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHLEFAVAALERD 236 Query: 218 GDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTVPG 274 G L A ++ + E D + +A+G P T+ + A ++ G + T Sbjct: 237 AQGTTLVA---QDGTRLEGFD----SVIWAVGRAPNTRDLGLEAAGIEVQSNGMVPT-DA 288 Query: 275 SSLTSVPGFFAAGDV 289 T+VPG +A GD+ Sbjct: 289 YQNTNVPGVYALGDI 303 >3Q6J-A nrPDB Length = 523 Score = 43.9 bits (102), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 52/203 (25%), Positives = 85/203 (41%), Gaps = 17/203 (8%) Query: 115 IILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLT 174 +ILA GA + +PG KG+ A + + V+GG +A E F Sbjct: 178 LILAVGAGPGTLDVPGVNA---KGVFDHATLVEELDYEPGSTVVVVGGSKTAVEYGCFFN 234 Query: 175 KYGSKVFMLVRKDHLRASTIMQKRAE-----KNEKIEIL--YNTVALEAKGDGKLLNALR 227 G + MLVR + L+ + RA K + +EI+ N +E +G++ + Sbjct: 235 ATGRRTVMLVRTEPLKLIKDNETRAYVLDRMKEQGMEIISGSNVTRIEEDANGRVQAVVA 294 Query: 228 I-KNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSL-TSVPGFFA 285 + N + ETD +F +G P + +A + D + + L TSVP +A Sbjct: 295 MTPNGEMRIETDF----VFLGLGEQPRSAELAKILGLDLGPKGEVLVNEYLQTSVPNVYA 350 Query: 286 AGDVQDSKYRQAITSAGSGCMAA 308 GD+ + + SGC AA Sbjct: 351 VGDLIGGPM-EMFKARKSGCYAA 372 >4EMJ-A nrPDB Length = 410 Score = 43.5 bits (101), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 52/220 (23%), Positives = 89/220 (40%), Gaps = 28/220 (12%) Query: 87 VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCD 146 V+ +D+ ++ L +D ++ DAI++ATG+ A+ M LPG + G+ Sbjct: 80 VTALDVQTRTISL-----DDGTTLSADAIVIATGSRARTMALPGSQL---PGVVTLRTY- 130 Query: 147 GAVPIFRNK-----PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK---- 197 G V + R+ L ++GGG CE A K G V +L D L + ++ Sbjct: 131 GDVQVLRDSWTSATRLLIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAW 190 Query: 198 -RAEKNE-KIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK 255 R E +++ T + G+G+L + ++ +G PA + Sbjct: 191 LRGLLTELGVQVELGTGVVGFSGEGQL------EQVMASDGRSFVADSALICVGAEPADQ 244 Query: 256 IVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYR 295 + + G I G++L G FA GDV R Sbjct: 245 LARQAGLACDRGVIVDHCGATLAK--GVFAVGDVASWPLR 282 >2X8H-A nrPDB Length = 598 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 60/216 (27%), Positives = 89/216 (41%), Gaps = 39/216 (18%) Query: 101 TEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVI 160 T+ N+ +T + IILATG K +PG Y GI++ + ++P F K L VI Sbjct: 239 TDKNQKVSTITGNKIILATGERPKYPEIPGAVEY---GITSDDLF--SLPYFPGKTL-VI 292 Query: 161 GGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEK------NEKIEILYNTVAL 214 G A E A FL G V ++VR LR Q+ AEK N ++ V Sbjct: 293 GASYVALECAGFLASLGGDVTVMVRSILLRG--FDQQMAEKVGDYMENHGVKFAKLCVPD 350 Query: 215 EAKGDGKLLNALRIKNTKKNEETDLPVSG--------------LFYAIGHTPATKIVAGQ 260 E K L++ +T+ N+ L V G + +A+G P V + Sbjct: 351 EIK-------QLKVVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKVLCE 403 Query: 261 ---VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSK 293 V D+ G + T+V +A GD+ K Sbjct: 404 TVGVKLDKNGRV-VCTDDEQTTVSNVYAIGDINAGK 438 >4FK1-A nrPDB Length = 304 Score = 43.1 bits (100), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 43/205 (20%), Positives = 85/205 (41%), Gaps = 17/205 (8%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGF-- 58 M + +IG+GPA A++ L RA + L++ +N GF Sbjct: 4 MKYIDCAVIGAGPAGLNASLVLGRARKQIALFDN----------NTNRNRVTQNSHGFIT 53 Query: 59 PDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 DG+ E + + K+ + E + V ++ + L+ +D + ++LA Sbjct: 54 RDGIKPEEFKEIGLNEVMKYPSVHYYEK-TVVMITKQSTGLFEIVTKDHTKYLAERVLLA 112 Query: 119 TGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIG-GGDSACEEAQFLTKYG 177 TG + +P Y+ K + +C CDG +++PL +I D + + + Sbjct: 113 TGMQEEFPSIPNVREYYGKSLFSCPYCDGWE--LKDQPLIIISENEDHTLHMTKLVYNWS 170 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKN 202 + + + + L + TIM + + KN Sbjct: 171 TDLVIATNGNEL-SQTIMDELSNKN 194 >5TR3-A nrPDB Length = 481 Score = 42.7 bits (99), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 48/149 (32%), Positives = 67/149 (44%), Gaps = 14/149 (9%) Query: 148 AVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH--LRASTIMQKRAEKNEKI 205 AVP K L VIG G E + G++V +L D + A T + K A+K Sbjct: 182 AVP----KRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTK 237 Query: 206 EILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS--GLFYAIGHTPATKIVAGQ--- 260 + L + L A+ G +N ++ T N E + ++ L A+G P T + Sbjct: 238 QGL--DIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSG 295 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAGDV 289 V DE GYI V TSVPG +A GDV Sbjct: 296 VTIDERGYI-FVDDYCATSVPGVYAIGDV 323 >1YQZ-A nrPDB Length = 438 Score = 42.4 bits (98), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 13/191 (6%) Query: 111 TTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEA 170 + D +IL+ GASA + + T+ + + D + + + V+G G + E Sbjct: 105 SYDKLILSPGASANSLGFESDITFTLRNLEDTDAIDQFIKANQVDKVLVVGAGYVSLEVL 164 Query: 171 QFLTKYGSKVFMLVRKD---HLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALR 227 + L + G ++ R D L + + Q ++ +K EI Y L + + N + Sbjct: 165 ENLYERGLHPTLIHRSDKINKLMDADMNQPILDELDKREIPYR---LNEEINAINGNEIT 221 Query: 228 IKNTKKNEETDLPVSGLFYAIGHTPATKIV-AGQVDTDEAGYIKTVPGSSLTSVPGFFAA 286 K + K E D+ + G +G P +K + + + D G+I V T+VP +A Sbjct: 222 FK-SGKVEHYDMIIEG----VGTHPNSKFIESSNIKLDRKGFI-PVNDKFETNVPNIYAI 275 Query: 287 GDVQDSKYRQA 297 GD+ S YR Sbjct: 276 GDIATSHYRHV 286 >3OC4-A nrPDB Length = 452 Score = 41.2 bits (95), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 55/229 (24%), Positives = 90/229 (39%), Gaps = 24/229 (10%) Query: 69 DRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHL 128 + +R Q + ++ V +D+ ++ WT E+ + + D +ILATGAS + Sbjct: 66 EELRRQKIQL---LLNREVVAMDVENQLIA-WTR-KEEQQWYSYDKLILATGASQFSTQI 120 Query: 129 PGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 G +T + AVP+ N + +AVIG G E FL K V + + Sbjct: 121 RGSQTEKLLKYKFLSGALAAVPLLENSQTVAVIGAGPIGMEAIDFLVKMKKTVHVFESLE 180 Query: 188 HLRASTI-------MQKRAEKNEKIEILYNTV-ALEAKGDGKLLNALRIKNTKKNEETDL 239 +L +QK EK I TV +E +G +L + E ++ Sbjct: 181 NLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETANGIVL---------ETSEQEI 231 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGD 288 +A+ P + ++ + I V TSVP FA GD Sbjct: 232 SCDSGIFALNLHPQLAYLDKKIQRNLDQTI-AVDAYLQTSVPNVFAIGD 279 >2AAQ-A nrPDB Length = 479 Score = 40.8 bits (94), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 46/145 (31%), Positives = 69/145 (47%), Gaps = 18/145 (12%) Query: 159 VIGGGDSACEEAQFLTKYGSKVFMLVRKDH-LRA--STIMQKRAE--KNEKIEILYNTVA 213 ++G G A E A L+ GSK +++R D LR+ S I E +N +E+L + Sbjct: 193 IVGAGYIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQV 252 Query: 214 LEAKGDGKLLNALRIKNT-----KKNEETDLP-VSGLFYAIGHTPATKIVAGQ---VDTD 264 E K K L+ L + + T +P V L +AIG P TK ++ + TD Sbjct: 253 KEVK---KTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTD 309 Query: 265 EAGYIKTVPGSSLTSVPGFFAAGDV 289 + G+I V T+V G +A GDV Sbjct: 310 DKGHI-IVDEFQNTNVKGIYAVGDV 333 >2BC1-A nrPDB Length = 490 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 67/286 (23%), Positives = 114/286 (39%), Gaps = 56/286 (19%) Query: 59 PDGLTGSELMDRMREQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIIL 117 P+GL S+ +E+ G ++ E+ V +D +K + E T D +I Sbjct: 91 PEGLFYSD-----KEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVE--TYDKLIF 143 Query: 118 ATGASAKRMHLPGEETYWQKGISACAVCDGA--VPIFRN-------------KPLAVIGG 162 ATG+ + G E + + A + V +++N K +AV+G Sbjct: 144 ATGSQPILPPIKGAEIK-EGSLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGA 202 Query: 163 GDSACEEAQFLTKYGSKVFMLVRKDHLRA-------STIMQKRAEKNEKIEILYNTVALE 215 G E A+ + G +V ++ D A + +M K E++ I++ + E Sbjct: 203 GYIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEH-GIQLAFGETVKE 261 Query: 216 AKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGS 275 G+GK+ + T KNE V + A+G P T + G++D G V Sbjct: 262 VAGNGKVEKII----TDKNE---YDVDMVILAVGFRPNTTLGNGKIDLFRNGAF-LVNKR 313 Query: 276 SLTSVPGFFAAGD--------VQDSKY--------RQAITSAGSGC 305 TS+PG +A GD +D+ Y R I +A + C Sbjct: 314 QETSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNAC 359 >6DU7-A nrPDB Length = 448 Score = 40.4 bits (93), Expect = 0.001, Method: Compositional matrix adjust. Identities = 54/198 (27%), Positives = 85/198 (42%), Gaps = 26/198 (13%) Query: 106 DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 + E + I++ATGA ++PG E G S +P + +A++G G Sbjct: 125 NGELIRAKHIVIATGAHPSIPNIPGAEL---GGSSDDVFAWEELP----ESVAILGAGYI 177 Query: 166 ACEEAQFLTKYGSKVFMLVRKDH-LRA--STIMQKRAEKNEKIEILYNT----VALEAKG 218 A E A L +G K + VR+D LR S I++ ++ E+ + +T V LE Sbjct: 178 AVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTHKVPVKLEKTT 237 Query: 219 DGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTVPGS 275 DG ++ + T S + +A G P K + V +E G+I+ V Sbjct: 238 DGITIHF--------EDGTSHTASQVIWATGRRPNVKGLQLEKAGVTLNERGFIQ-VDEY 288 Query: 276 SLTSVPGFFAAGDVQDSK 293 T V G +A GDV K Sbjct: 289 QNTVVEGIYALGDVTGEK 306 >4DNA-A nrPDB Length = 463 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 58/195 (29%), Positives = 82/195 (42%), Gaps = 30/195 (15%) Query: 110 VTTDAIILATGAS-AKRMHLPGEETYWQKGISACAVCDGA--VPIFRNKPLAVIGGGDSA 166 VT + I++A G + LPG E C + A +P L + GGG A Sbjct: 132 VTAERIVIAVGGHPSPHDALPGHEL--------CITSNEAFDLPALPESIL-IAGGGYIA 182 Query: 167 CEEAQFLTKYGSKVFMLVRKDHL--RASTIMQK--RAEKNEK-IEILYNTV--ALEAKGD 219 E A G K ++ R + R M++ A EK I IL + ++ A D Sbjct: 183 VEFANIFHGLGVKTTLIYRGKEILSRFDQDMRRGLHAAMEEKGIRILCEDIIQSVSADAD 242 Query: 220 GKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTVPGSS 276 G+ R+ T K+ E + + A+G P T + A V T+E G I V S Sbjct: 243 GR-----RVATTMKHGE--IVADQVMLALGRMPNTNGLGLEAAGVRTNELGAI-IVDAFS 294 Query: 277 LTSVPGFFAAGDVQD 291 TS PG +A GDV D Sbjct: 295 RTSTPGIYALGDVTD 309 >4LA1-A nrPDB Length = 602 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 36/101 (35%), Positives = 50/101 (49%), Gaps = 8/101 (7%) Query: 101 TEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVI 160 TE N+ +T + IILATG K +PG Y GI++ + ++P F K L V+ Sbjct: 245 TEKNKKVSTITGNKIILATGERPKYPEIPGAIEY---GITSDDLF--SLPYFPGKTL-VV 298 Query: 161 GGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEK 201 G A + A FL G V ++VR LR Q+ AEK Sbjct: 299 GASYVALKCAGFLASLGGDVTVMVRSILLRG--FDQQMAEK 337 >5W1J-A nrPDB Length = 584 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 56/204 (27%), Positives = 82/204 (40%), Gaps = 30/204 (14%) Query: 110 VTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRN--KPLAVIGGGDSAC 167 +TT+ II+ATG + +PG + Y GI++ D + N K L V G + Sbjct: 242 ITTNTIIVATGERPRYPPIPGAKEY---GITS----DDLFTLDHNPGKTLCV-GASYVSL 293 Query: 168 EEAQFLTKYGSKVFMLVRKDHLRA---------STIMQKRAEKNEKIEILYNTVALEAKG 218 E A FL+ G V ++VR LR S + K K + + + LE Sbjct: 294 ECAGFLSSIGCDVTVMVRSIFLRGFDQQMAGLISDYIAKYGVKFVRPCVPTSVRCLEEYD 353 Query: 219 --DGKLLNALRIKNTKKNEETDLPVSGLF----YAIGHTPATKIVAGQ-VDTDEAGYIKT 271 GK L I + E P F +A+G P T + Q VD Sbjct: 354 PESGK----LAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKTTNGRVV 409 Query: 272 VPGSSLTSVPGFFAAGDVQDSKYR 295 V T+VP +A GDV ++ Y+ Sbjct: 410 VDDEERTNVPNIYAIGDVSNAGYQ 433 >1GEU-A nrPDB Length = 450 Score = 38.9 bits (89), Expect = 0.003, Method: Compositional matrix adjust. Identities = 53/195 (27%), Positives = 85/195 (43%), Gaps = 29/195 (14%) Query: 106 DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDG--AVPIFRNKPLAVIGGG 163 + E +T D I++ATG +PG E GI + DG A+P + +AV+G G Sbjct: 126 NGETITADHILIATGGRPSHPDIPGVE----YGIDS----DGFFALPALPER-VAVVGAG 176 Query: 164 DSACEEAQFLTKYGSKVFM-------LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEA 216 E + G+K + L D + + T+++ + ++ A+ Sbjct: 177 YIGVELGGVINGLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEGPQLHTNAIPKAVVK 236 Query: 217 KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYIKTVP 273 DG L L +++ + ET V L +AIG PA + A V T+E GYI V Sbjct: 237 NTDGSL--TLELEDGRS--ET---VDCLIWAIGREPANDNINLEAAGVKTNEKGYI-VVD 288 Query: 274 GSSLTSVPGFFAAGD 288 T++ G +A GD Sbjct: 289 KYQNTNIEGIYAVGD 303 >5TWC-A nrPDB Length = 344 Score = 38.5 bits (88), Expect = 0.003, Method: Compositional matrix adjust. Identities = 72/324 (22%), Positives = 140/324 (43%), Gaps = 27/324 (8%) Query: 6 VTIIGSGPAAHTAAIY--LARAEIKPILYEGMMANGIAAGGQLTTTTE--IENFPGFPDG 61 VTIIG GP+ A+ Y L ++ I + + GG++ E I + G Sbjct: 4 VTIIGGGPSGLYASFYAGLRDMSVRLIDVQSEL------GGKMRIYPEKIIWDIGGIAPK 57 Query: 62 LTGSELMDRMREQSTKFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 L D ++ Q F E+ + E V VD+ K + + E E T+ A+I+A G Sbjct: 58 PCHEILKDTIK-QGLYFKPEVHLNERV--VDIRKKAERHFEVETEAGEIYTSKAVIIAIG 114 Query: 121 A---SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 A + K++ + G E Y + + F++K + + GGG++A + A + K Sbjct: 115 AGIINPKQLDVKGVERYQLTNLHYVV---QSYRRFKDKDVLISGGGNTALDWAHDIAKIA 171 Query: 178 SKVFMLVRKDHLRASTIMQKRA-EKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEE 236 V ++ RK+ + M+ + N K+ L D ++ + +++ + + Sbjct: 172 KSVTVVYRKEDVSGHEAMKTLVTDLNVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDR 231 Query: 237 TDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDV--QD 291 + + + G ++ + ++D + +K G++ TS+PG +A GD+ D Sbjct: 232 HTVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGF-GNTTTSIPGIYACGDIVYHD 290 Query: 292 SKYRQAITSAGSGCMAALDAEKYL 315 +K ++ G AA A+ Y+ Sbjct: 291 AKSHLIASAFSDGANAANLAKTYI 314 >4NTC-A nrPDB Length = 335 Score = 38.1 bits (87), Expect = 0.006, Method: Compositional matrix adjust. Identities = 68/295 (23%), Positives = 110/295 (37%), Gaps = 28/295 (9%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYE-GMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V IIG+GPA + A LAR ++++ G+ N T + N G+ D Sbjct: 17 VLIIGAGPAGLSTATGLARQLHTAVVFDSGVYRNA--------KTQHMHNVLGW-DHRNP 67 Query: 65 SELMDRMR-EQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +EL R + +T++ T + + + +L+ + + ++LATG Sbjct: 68 AELRAAGRADLTTRYSTIQFQNSTIEAIRQVETNQLFEARDNEGHSWYGRKVVLATGVRD 127 Query: 124 KRMHLPGEETYWQKGISACAVCDG-------AVPIFRNKPLAVIGGGDSACEEAQFLTKY 176 + + G W GI C CDG V + P+A A A+ + Sbjct: 128 IPLDIEGYSECWANGIYHCLFCDGYEERGQETVGVLALGPIA---NPARALHLARMALRL 184 Query: 177 GSKVFMLVRKDHLRASTIMQKRAEK---NEKIEILYNTVALEAKGDGKLLNALRIKNTKK 233 V + + A I Q E ++ + KGD + + ++ Sbjct: 185 SESVTIYTNGNEQLAKEIQQAAEESPVGASGLKFEARPIRRFEKGDVAKTVIVHLGESES 244 Query: 234 NEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGD 288 E L + G P K +A ++ E G I T P TSVPG FA GD Sbjct: 245 KTEGFLVYNPQTEVNG--PFAKQLA--LNMTEGGDILTTPPFYETSVPGVFAVGD 295 >4KPR-E nrPDB Length = 499 Score = 37.4 bits (85), Expect = 0.008, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 90/213 (42%), Gaps = 25/213 (11%) Query: 96 PFKLWTEFNEDAEPV-TTDAIILATGASAKRMHLPGEETYWQKGISACAVCDG--AVPIF 152 P K+ N+ E V + + ++ATG + + +PG++ Y C D ++P Sbjct: 137 PHKIMATNNKGKEKVYSAERFLIATGERPRYLGIPGDKEY-------CISSDDLFSLPYC 189 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA--STIMQKRAEKNEK--IEIL 208 K L V+G A E A FL G V ++VR LR + K E E+ I+ + Sbjct: 190 PGKTL-VVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFI 248 Query: 209 YNTV-----ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQ--- 260 V +EA G+L + K+T E + + + A+G T+ + + Sbjct: 249 RQFVPTKIEQIEAGTPGRL--KVTAKSTNSEETIEDEFNTVLLAVGRDSCTRTIGLETVG 306 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSK 293 V +E V T+VP +A GD+ + K Sbjct: 307 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEGK 339 >4YWO-A nrPDB Length = 462 Score = 36.6 bits (83), Expect = 0.013, Method: Compositional matrix adjust. Identities = 83/340 (24%), Positives = 132/340 (38%), Gaps = 52/340 (15%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYE-----GMMAN-GIAAGGQLTTTTEI----- 52 +K+ IIG G A A I +KP+L G N G ++ EI Sbjct: 16 HKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAR 75 Query: 53 -----ENFPGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDA 107 E +P F L+ MR+ TK+ + V + ++ F + Sbjct: 76 EVTGSEVYPPFSSFQEKDGLVQEMRK--TKYEDLLSYYDVELIQGEAR-FISPHAVKVNG 132 Query: 108 EPVTTDAIILATGASAKRMHLPGEET--YWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 + + + ++ATG+S +PG + +W + P R LAVIGG Sbjct: 133 QVIEAEKFVIATGSSPLIPRIPGLDKVGFWTNR-------EALSPDRRIDSLAVIGGRAL 185 Query: 166 ACEEAQFLTKYGSKVFMLVRK-----DHLRASTIMQKRAEKNEKIEILYNTVALEA-KGD 219 A E AQ ++ +V +L R D +++ +R +N+ + ++ E KG Sbjct: 186 ALEFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVKEVRKGA 245 Query: 220 GKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKI---VAGQVDTDEAGYIKTVPGSS 276 GK+ + K E D + A G P + AG V +E G IK V Sbjct: 246 GKI-----VITDKGEVEAD----EILLATGRKPNVDLGLENAG-VRLNERGGIK-VDDEL 294 Query: 277 LTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLT 316 T P +AAGDV K +A+ +G ++ E LT Sbjct: 295 RTDNPHIYAAGDVLGGKMLEAL----AGRQGSIATENALT 330 >2EQ6-A nrPDB Length = 464 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 56/198 (28%), Positives = 86/198 (43%), Gaps = 21/198 (10%) Query: 102 EFNEDAEPVTTDAIILATGASAKRMH-LPGEETYWQKGISACAVCDGAVPIFRNKPLAVI 160 E E ++ILATG+ + P E W A V +G +P K L VI Sbjct: 122 EVEVGGERYGAKSLILATGSEPLELKGFPFGEDVWDS-TRALKVEEG-LP----KRLLVI 175 Query: 161 GGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-----STIMQKRAEKNEKIEILYNT--VA 213 GGG E Q + G++V ++ + + + +RA + E I + T V Sbjct: 176 GGGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRTKTKAVG 235 Query: 214 LEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIK 270 E K DG +R++ + E ++ V + A+G P T+ + V DE G+I+ Sbjct: 236 YEKKKDGL---HVRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGLGLEKAGVKVDERGFIR 292 Query: 271 TVPGSSLTSVPGFFAAGD 288 V TSVPG +A GD Sbjct: 293 -VNARMETSVPGVYAIGD 309 >1NHQ-A nrPDB Length = 447 Score = 36.2 bits (82), Expect = 0.019, Method: Compositional matrix adjust. Identities = 55/199 (27%), Positives = 81/199 (40%), Gaps = 23/199 (11%) Query: 113 DAIILATGASAKRMHLPGEE---TYWQKGIS-ACAVCDGAV-PIFRNKPLAVIGGGDSAC 167 D +I++ GA + +PG++ Y +G A + V P N + VIG G Sbjct: 105 DKLIISPGAVPFELDIPGKDLDNIYLMRGRQWAIKLKQKTVDPEVNN--VVVIGSGYIGI 162 Query: 168 EEAQFLTKYGSKVFMLVRKDH-------LRASTIMQKRAEKNEKIEILYNTVALEAKGDG 220 E A+ K G KV ++ D + ++ + E N I I +GDG Sbjct: 163 EAAEAFAKAGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEAN-NITIATGETVERYEGDG 221 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSV 280 ++ + KN + DL V A+G P T + G ++ G IKT TS Sbjct: 222 RVQKVVTDKNAY---DADLVV----VAVGVRPNTAWLKGTLELHPNGLIKT-DEYMRTSE 273 Query: 281 PGFFAAGDVQDSKYRQAIT 299 P FA GD KY A T Sbjct: 274 PDVFAVGDATLIKYNPADT 292 >6N7F-A nrPDB Length = 453 Score = 35.0 bits (79), Expect = 0.038, Method: Compositional matrix adjust. Identities = 42/150 (28%), Positives = 67/150 (44%), Gaps = 26/150 (17%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVAL 214 K AV+G G A E A L GSK + +R D R+ +++L + +A+ Sbjct: 171 KRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDR-------PLRSFDKTIVDVLVDEMAV 223 Query: 215 EAKGDGKLLN-----ALRIKNTKKN------EETDLPVSGLFYAIGHTPATK---IVAGQ 260 +G L+ A +KNT ++ + ++ V L +AIG P + + Sbjct: 224 ----NGPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAIGRKPNLEGFSLDKTG 279 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQ 290 V ++ GYI+T TSV G +A GDV Sbjct: 280 VTLNDKGYIET-DAYENTSVKGIYAVGDVN 308 >5NMX-A nrPDB Length = 425 Score = 35.0 bits (79), Expect = 0.038, Method: Compositional matrix adjust. Identities = 17/56 (30%), Positives = 31/56 (55%), Gaps = 11/56 (19%) Query: 5 KVTIIGSGPAAHTAA---------IYLARAEIKPILYEGMMANGIAAGGQLTTTTE 51 +V I+G+GP+ H A ++L+R E+KP+ EG+ + + LT+ +E Sbjct: 186 RVLIVGAGPSGHDMALHISYVSKEVFLSRKELKPV--EGLFPDNVTEKPLLTSLSE 239 Score = 28.9 bits (63), Expect = 3.0, Method: Compositional matrix adjust. Identities = 47/215 (21%), Positives = 87/215 (40%), Gaps = 33/215 (15%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG----------IAAGGQLTTTTEIEN 54 +V ++G+GP+ TAA YL +A + +++E G ++ G+ ++ +N Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGGTWNYTDETWMSEDGRPVYSSMYQN 62 Query: 55 -----------FPGFP-DGLTGS-----ELMDRMREQSTKFGTEIITETVSKVDLSSKPF 97 FP FP + GS E++ + F + + V+ Sbjct: 63 LFVNLPKELMAFPDFPFHDIEGSYVPSKEVLKYFDNFTDAFDLRKLIKLQHHVENVRPCE 122 Query: 98 KLW----TEFNEDAE-PVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIF 152 W T+ E DA+++ TG + ++ E + +G A + F Sbjct: 123 SGWLVTVTDLTTMVEHSFEFDAVVVCTGQTWCPLYPDVEGRSFFRGRLTHAHEFRSPEPF 182 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 RNK + ++G G S + A ++ Y SK L RK+ Sbjct: 183 RNKRVLIVGAGPSGHDMALHIS-YVSKEVFLSRKE 216 >6B4O-A nrPDB Length = 452 Score = 34.3 bits (77), Expect = 0.066, Method: Compositional matrix adjust. Identities = 51/186 (27%), Positives = 81/186 (43%), Gaps = 19/186 (10%) Query: 111 TTDAIILATGASAKRMHLPGEETYWQ-KGISACAVCDGAVPIFRNKPLAVIGGGDSACEE 169 T I++ATG K++ +PGEE G A +P K + +G G A E Sbjct: 133 TAPHILIATGGRPKKLGIPGEEYALDSNGFFALE----EMP----KRVVFVGAGYIAAEL 184 Query: 170 AQFLTKYGSKVFMLVRKDH-LRASTIM--QKRAEKNEKIEILYNTVALEAKGDGKLLNAL 226 A L G++ R + LR+ M +K E+ +++ + + A AK + N Sbjct: 185 AGTLHGLGAETHWAFRHERPLRSFDDMLSEKVVERYQEMGMQIHPNATPAKIEKTAQNEY 244 Query: 227 RIKNTKKNEETDLPVSGLFYAIGHTPATKIVA---GQVDTDEAGYIKTVPGSSLTSVPGF 283 I T +N E+ + + + G P T + +V DE GY+K V T+ G Sbjct: 245 VI--TFENGES-ITTDAVIFGTGRQPNTDQLGLENTKVALDEKGYVK-VDKFQNTTQNGI 300 Query: 284 FAAGDV 289 +A GDV Sbjct: 301 YAVGDV 306 >3LAD-A nrPDB Length = 476 Score = 34.3 bits (77), Expect = 0.082, Method: Compositional matrix adjust. Identities = 50/196 (25%), Positives = 80/196 (40%), Gaps = 15/196 (7%) Query: 101 TEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKP--LA 158 T + ++ + T+ +ILA+G+ K + +P + + D F+N P L Sbjct: 132 TAADGSSQVLDTENVILASGS--KPVEIPPAPVDQDVIVDSTGALD-----FQNVPGKLG 184 Query: 159 VIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKG 218 VIG G E + G++V +L D + Q E + + + L A+ Sbjct: 185 VIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLGARV 244 Query: 219 DGKLLN--ALRIKNTKKNEETDLPVSGLFYAIGHTPAT-KIVAGQ--VDTDEAGYIKTVP 273 G + + +K E L A+G P T ++A V DE G+I V Sbjct: 245 TGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLDERGFI-YVD 303 Query: 274 GSSLTSVPGFFAAGDV 289 TSVPG +A GDV Sbjct: 304 DYCATSVPGVYAIGDV 319 >1EBD-A nrPDB Length = 455 Score = 33.9 bits (76), Expect = 0.087, Method: Compositional matrix adjust. Identities = 49/194 (25%), Positives = 84/194 (43%), Gaps = 20/194 (10%) Query: 105 EDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGD 164 + A+ T I+ATG+ + + LP + + S A+ G VP K L VIGGG Sbjct: 127 DSAQTYTFKNAIIATGS--RPIELPNFKFSNRILDSTGALNLGEVP----KSLVVIGGGY 180 Query: 165 SACEEAQFLTKYGSKVFMLVRKDHL------RASTIMQKRAEKNEKIEILYNTVALEAKG 218 E +G+KV +L + + + I++KR +K + +E++ N + AKG Sbjct: 181 IGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKK-KGVEVVTNAL---AKG 236 Query: 219 DGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQ---VDTDEAGYIKTVPGS 275 + + + + E + + +G P T + + + G I+ V Sbjct: 237 AEEREDGVTVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIE-VDQQ 295 Query: 276 SLTSVPGFFAAGDV 289 TSVP FA GD+ Sbjct: 296 CRTSVPNIFAIGDI 309 >2CFY-A nrPDB Length = 521 Score = 32.7 bits (73), Expect = 0.20, Method: Compositional matrix adjust. Identities = 52/213 (24%), Positives = 90/213 (42%), Gaps = 25/213 (11%) Query: 96 PFKLWTEFNEDAEPV-TTDAIILATGASAKRMHLPGEETYWQKGISACAVCDG--AVPIF 152 P ++ N+ E + + + ++ATG + + +PG++ Y C D ++P Sbjct: 159 PHRIKATNNKGKEKIYSAERFLIATGERPRYLGIPGDKEY-------CISSDDLFSLPYC 211 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA--STIMQKRAEKNEK--IEIL 208 K L V+G A E A FL G V ++VR LR + K E E+ I+ + Sbjct: 212 PGKTL-VVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKIGEHMEEHGIKFI 270 Query: 209 YNTV-----ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQ--- 260 V +EA G+L + ++T E + + + AIG T+ + + Sbjct: 271 RQFVPIKVEQIEAGTPGRL--RVVAQSTNSEEIIEGEYNTVMLAIGRDACTRKIGLETVG 328 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSK 293 V +E V T+VP +A GD+ + K Sbjct: 329 VKINEKTGKIPVTDEEQTNVPYIYAIGDILEDK 361 >5U8W-A nrPDB Length = 481 Score = 32.3 bits (72), Expect = 0.32, Method: Compositional matrix adjust. Identities = 44/152 (28%), Positives = 59/152 (38%), Gaps = 20/152 (13%) Query: 148 AVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLR-------ASTIMQKRAE 200 AVP K L VIG G E + G++V +L D A ++ + Sbjct: 182 AVP----KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTK 237 Query: 201 KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT-KIVAG 259 + I + A E K + + T N E L A+G P T ++A Sbjct: 238 QGLNIRLGARVTASEVKK-----KQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAA 292 Query: 260 Q--VDTDEAGYIKTVPGSSLTSVPGFFAAGDV 289 V DE G+I V TSVPG FA GDV Sbjct: 293 DSGVTLDERGFI-YVDDHCKTSVPGVFAIGDV 323 >2QAE-A nrPDB Length = 468 Score = 31.2 bits (69), Expect = 0.54, Method: Compositional matrix adjust. Identities = 49/197 (24%), Positives = 82/197 (41%), Gaps = 25/197 (12%) Query: 108 EPVTTDAIILATGASAKRM-HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSA 166 E + T I+ATG+ + LP +E A A+ VP K + VIGGG Sbjct: 133 EMLETKKTIIATGSEPTELPFLPFDEKVVLSSTGALAL--PRVP----KTMVVIGGGVIG 186 Query: 167 CEEAQFLTKYGSKVFMLVRKDHL------RASTIMQKRAEKNEKIEILYNTVALEAKGDG 220 E + G++V ++ + + KNEK++ + +T + +G Sbjct: 187 LELGSVWARLGAEVTVVEFAPRCAPTLDEDVTNALVGALAKNEKMKFMTSTKVVGGTNNG 246 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT------KIVAGQVDTDEAGYIKTVPG 274 + +L ++ ET + L ++G P T KI V +E G++K + Sbjct: 247 DSV-SLEVEGKNGKRET-VTCEALLVSVGRRPFTGGLGLDKI---NVAKNERGFVK-IGD 300 Query: 275 SSLTSVPGFFAAGDVQD 291 TS+P +A GDV D Sbjct: 301 HFETSIPDVYAIGDVVD 317 >1ONF-A nrPDB Length = 500 Score = 31.2 bits (69), Expect = 0.70, Method: Compositional matrix adjust. Identities = 42/193 (21%), Positives = 76/193 (39%), Gaps = 20/193 (10%) Query: 137 KGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL------R 190 KGI D I +K + ++G G A E + + G ++ R + + Sbjct: 159 KGIENTISSDEFFNIKESKKIGIVGSGYIAVELINVIKRLGIDSYIFARGNRILRKFDES 218 Query: 191 ASTIMQKRAEKNE-KIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIG 249 +++ +KN I + V ++ D L ++ + + + E D + Y +G Sbjct: 219 VINVLENDMKKNNINIVTFADVVEIKKVSDKNL--SIHLSDGRIYEHFD----HVIYCVG 272 Query: 250 HTPAT---KIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCM 306 +P T K+ V+T+ YI V + TSV +A GD K + I + Sbjct: 273 RSPDTENLKLEKLNVETNN-NYI-VVDENQRTSVNNIYAVGDCCMVKKSKEIEDL--NLL 328 Query: 307 AALDAEKYLTSLE 319 + E+YL E Sbjct: 329 KLYNEERYLNKKE 341 >2YAU-A nrPDB Length = 511 Score = 30.8 bits (68), Expect = 0.79, Method: Compositional matrix adjust. Identities = 48/198 (24%), Positives = 79/198 (39%), Gaps = 30/198 (15%) Query: 108 EPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGDSA 166 E + T+ I++ATG+ R+ +PG+E C + A + K + +GGG A Sbjct: 169 ETLDTEYILIATGSWPTRLGVPGDEF--------CITSNEAFYLEDAPKRMLCVGGGYIA 220 Query: 167 CEEAQFLTKY---GSKVFMLVRKDH-LRA------STIMQKRAEKNEKIEILYNTVALEA 216 E A Y G V + R D LR ++ ++ ++ N + Sbjct: 221 VEFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITK 280 Query: 217 KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP---ATKIVAGQVDTDEAGYIKTVP 273 DG + N+ T+ + AIG P A ++ V T + G ++ V Sbjct: 281 NEDGS-------NHVHFNDGTEEDYDQVMLAIGRVPRSQALQLDKAGVRTGKNGAVQ-VD 332 Query: 274 GSSLTSVPGFFAAGDVQD 291 S TSV +A GDV + Sbjct: 333 AYSKTSVDNIYAIGDVTN 350 >2BXR-A nrPDB Length = 527 Score = 30.8 bits (68), Expect = 0.91, Method: Compositional matrix adjust. Identities = 17/46 (36%), Positives = 25/46 (54%), Gaps = 2/46 (4%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL--RASTIMQKRAE 200 + VIGGG S A+ LT+YG V +L +D + R TI + + Sbjct: 16 VVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVD 61 >3L8K-A nrPDB Length = 466 Score = 30.4 bits (67), Expect = 0.93, Method: Compositional matrix adjust. Identities = 43/190 (22%), Positives = 72/190 (37%), Gaps = 27/190 (14%) Query: 112 TDAIILATGASAKRMHLPGEETYWQKGISACAVCD---GAVPIFRNKP--LAVIGGGDSA 166 T +I+A+GA ++ LPG E C D G FR P + +IG G Sbjct: 133 TRYMIIASGAETAKLRLPGVEY--------CLTSDDIFGYKTSFRKLPQDMVIIGAGYIG 184 Query: 167 CEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNAL 226 E A G + ++ D RA + E + + L + + L K + + Sbjct: 185 LEIASIFRLMGVQTHIIEMLD--RALITL----EDQDIVNTLLSILKLNIKFNSPVTEVK 238 Query: 227 RIKN--------TKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLT 278 +IK+ TK + + + + A G P A ++ + V + T Sbjct: 239 KIKDDEYEVIYSTKDGSKKSIFTNSVVLAAGRRPVIPEGAREIGLSISKTGIVVDETMKT 298 Query: 279 SVPGFFAAGD 288 ++P FA GD Sbjct: 299 NIPNVFATGD 308 >4QB5-A nrPDB Length = 148 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 27/67 (40%), Gaps = 5/67 (7%) Query: 7 TIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSE 66 T I PA H L A P + A GIA GG T E PGF DG G Sbjct: 73 TPINGQPATHGNGSTLGFAAQSPEQCDAFHAAGIANGG-----TTCEEPPGFRDGAVGKL 127 Query: 67 LMDRMRE 73 + +R+ Sbjct: 128 YLAYLRD 134 >3WE0-A nrPDB Length = 580 Score = 29.3 bits (64), Expect = 2.2, Method: Compositional matrix adjust. Identities = 29/93 (31%), Positives = 42/93 (45%), Gaps = 15/93 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 +V I+G+G A AA L + +KP++YE GG+L + + F G DG+ Sbjct: 67 EVAIVGAGIAGLVAAYELMKLGLKPVVYEAS-----KMGGRLRS----QAFNG-TDGIIA 116 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPF 97 R ST F V K+ L +KPF Sbjct: 117 ELGGMRFPVSSTAF-----YHYVDKLGLETKPF 144 >4Y4M-A nrPDB Length = 290 Score = 29.3 bits (64), Expect = 2.7, Method: Compositional matrix adjust. Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 +V V I+G+GP+ T A YLA+ K ++ E +A Sbjct: 57 IVEADVVIVGAGPSGLTCARYLAKEGFKVVVLERHLA 93 >5JCN-A nrPDB Length = 451 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 85/311 (27%), Positives = 128/311 (41%), Gaps = 41/311 (13%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIA-------AGGQLTTTTEIENF 55 H K I+G G AA AA A+ +KP + +A + G L Sbjct: 22 HFKYVILGGGVAAGYAAREFAKQGVKPGELAIISKEAVAPYERPALSKGYLFPQNA-ARL 80 Query: 56 PGFPDGLTGSELMDRMREQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDA 114 PGF GS + E ++ G E+I T + K DL+SK T + T + Sbjct: 81 PGF-HVCVGSGGERLLPEWYSEKGIELILSTEIVKADLASK-----TLTSAVGATFTYEI 134 Query: 115 IILATGASAKRMHLPGEETYWQKGISACAVCD------GAVPIFRNKPLAVIGGGDSACE 168 +I+ATG+S ++ G + I D A+ + ++GGG E Sbjct: 135 LIIATGSSVIKLSDFGTQGADSNNILYLREVDDADKLVAAIQAKKGGKAVIVGGGYIGLE 194 Query: 169 EAQFLTKYGSKVFMLVRK----DHLRASTI--MQKRAEKNEKIEILYNTVAL----EAKG 218 + L V M+ + L + I + N+ ++I+ TVA+ +A G Sbjct: 195 LSAALKINDFDVTMVFPEPWCMPRLFTADIAAFYESYYTNKGVKIVKGTVAVGFDADANG 254 Query: 219 DGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLT 278 D + A+ +KN E D+ V G +G P T + GQV +E G IKT T Sbjct: 255 D---VTAVNLKNGSV-LEADIVVVG----VGGRPLTTLFKGQV-AEEKGGIKT-DAFFET 304 Query: 279 SVPGFFAAGDV 289 SVPG +A GDV Sbjct: 305 SVPGVYAVGDV 315 >5VHF-V nrPDB Length = 183 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 26/49 (53%) Query: 67 LMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAI 115 L+ R+R K G +I+ + S++ L+ KL + EDAE + AI Sbjct: 72 LIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAI 120 >1ZDL-A nrPDB Length = 517 Score = 28.9 bits (63), Expect = 3.3, Method: Compositional matrix adjust. Identities = 39/147 (26%), Positives = 63/147 (42%), Gaps = 17/147 (11%) Query: 159 VIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-----STIMQKRAEKNEKIEILYNTVA 213 V+G A E A FLT G +++R LR S+++ + E + + L V Sbjct: 216 VVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHME-SHGTQFLKGCVP 274 Query: 214 LEAKGDGKL-LNALRI--KNTKKNEETDLPVSGLFYAIGHTPATKIV----AGQVDTDEA 266 K KL N L++ ++ +E + +AIG P T+ + AG + T+ Sbjct: 275 SHIK---KLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAG-ISTNPK 330 Query: 267 GYIKTVPGSSLTSVPGFFAAGDVQDSK 293 V TSVP +A GDV + + Sbjct: 331 NQKIIVDAQEATSVPHIYAIGDVAEGR 357 >6FEA-B nrPDB Length = 475 Score = 28.5 bits (62), Expect = 3.6, Method: Compositional matrix adjust. Identities = 23/81 (28%), Positives = 37/81 (45%), Gaps = 8/81 (9%) Query: 136 QKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG-SKVFMLVRKDHLRASTI 194 ++GI+ A+ D A F NK +A+ G D AQF + V +L+ D Sbjct: 308 ERGIALDALADLAHMFFANKKVAIFGHPDLVLGLAQFCMEVELEPVLLLIGDDQ------ 361 Query: 195 MQKRAEKNEKIEILYNTVALE 215 + +K+ +IE L NT + Sbjct: 362 -GNKYKKDPRIEELKNTAHFD 381 >1LQU-A nrPDB Length = 456 Score = 28.5 bits (62), Expect = 3.8, Method: Compositional matrix adjust. Identities = 36/144 (25%), Positives = 59/144 (40%), Gaps = 48/144 (33%) Query: 6 VTIIGSGPAAHTAAIYLARA--------------EIKPILYEGMMANGIAAGGQLTTTTE 51 + I+GSGP+A AA L +A E+ P + G++ +G+A Sbjct: 6 IAIVGSGPSAFFAAASLLKAADTTEDLDMAVDMLEMLPTPW-GLVRSGVA---------- 54 Query: 52 IENFPGFPDGLTGSELMDRMREQS--TKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEP 109 P P + S+ ++ E FG ++ E V +LS + Sbjct: 55 ----PDHPKIKSISKQFEKTAEDPRFRFFGNVVVGEHVQPGELSER-------------- 96 Query: 110 VTTDAIILATGASAKRM-HLPGEE 132 DA+I A GA + RM ++PGE+ Sbjct: 97 --YDAVIYAVGAQSDRMLNIPGED 118 >2WOV-A nrPDB Length = 495 Score = 28.5 bits (62), Expect = 4.6, Method: Compositional matrix adjust. Identities = 52/199 (26%), Positives = 77/199 (38%), Gaps = 32/199 (16%) Query: 108 EPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKP---LAVIGGGD 164 E + D I+LATG+ + +PG I C + A + +P + +GGG Sbjct: 152 ERLQADHILLATGSWPQMPAIPG--------IEHCISSNEA--FYLPEPPRRVLTVGGGF 201 Query: 165 SACEEAQFLTKY---GSKVFMLVRKDHLRASTIMQKRAEKNEK-----IEILYNTVALEA 216 + E A Y G KV + R + + R E ++ IEI+ N + Sbjct: 202 ISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIREEVTKQLTANGIEIMTNENPAKV 261 Query: 217 KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK-IVAGQVD---TDEAGYIKTV 272 LN K+ L V + AIG P T + G V T + G V Sbjct: 262 S-----LNTDGSKHVTFESGKTLDVDVVMMAIGRIPRTNDLQLGNVGVKLTPKGGV--QV 314 Query: 273 PGSSLTSVPGFFAAGDVQD 291 S T+VP +A GD+ D Sbjct: 315 DEFSRTNVPNIYAIGDITD 333 >6EPE-S nrPDB Length = 530 Score = 28.1 bits (61), Expect = 5.9, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 26/49 (53%) Query: 67 LMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAI 115 L+ R+R K G +I+ + S++ L+ KL + EDAE + AI Sbjct: 390 LIIRLRHNVIKTGVRMISLSYSRISLADIAQKLQLDSPEDAEFIVAKAI 438 >5J5Z-A nrPDB Length = 496 Score = 27.7 bits (60), Expect = 6.3, Method: Compositional matrix adjust. Identities = 13/28 (46%), Positives = 17/28 (60%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYE 33 VT+IGSGP + AAI A+ K + E Sbjct: 31 VTVIGSGPGGYVAAIKAAQLGFKTVCIE 58 >5TUF-A nrPDB Length = 409 Score = 27.7 bits (60), Expect = 6.4, Method: Compositional matrix adjust. Identities = 16/43 (37%), Positives = 21/43 (48%), Gaps = 2/43 (4%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQ 45 H K+ +IG G A A +L R P+L E A + GGQ Sbjct: 25 HIKILVIGVGVAGPAVAYWLKRFGFSPVLIEKSAA--VRKGGQ 65 >3A9C-A nrPDB Length = 338 Score = 27.7 bits (60), Expect = 6.5, Method: Compositional matrix adjust. Identities = 25/103 (24%), Positives = 40/103 (38%), Gaps = 1/103 (0%) Query: 138 GISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK 197 GI V D A + V+ G DS + K G+ + L K+H R T++ Sbjct: 192 GIPVIYVVDSAARHYMKMTDKVVMGADSITVNGAVINKIGTALIALTAKEH-RVWTMIAA 250 Query: 198 RAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLP 240 K +L V +E + +++ +K KN E P Sbjct: 251 ETYKFHPETMLGQLVEIEMRDPTEVIPEDELKTWPKNIEVWNP 293 >3LXD-A nrPDB Length = 415 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 46/112 (41%), Gaps = 18/112 (16%) Query: 77 KFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQ 136 K G E+++ +D ++ KL D + +I ATG +R+ G + Sbjct: 83 KLGAEVVS-----LDPAAHTVKL-----GDGSAIEYGKLIWATGGDPRRLSCVGADL--- 129 Query: 137 KGISACAVCDGAVPIFRN-----KPLAVIGGGDSACEEAQFLTKYGSKVFML 183 G+ A + A + K VIGGG E A LTK+G V +L Sbjct: 130 AGVHAVRTKEDADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLL 181 >4Y4N-A nrPDB Length = 286 Score = 27.7 bits (60), Expect = 7.3, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 21/33 (63%), Gaps = 2/33 (6%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 +A++GGG S A+++ K G KV +L R HL Sbjct: 55 VAIVGGGPSGLTAARYIAKEGYKVVVLER--HL 85 >3II4-A nrPDB Length = 466 Score = 27.3 bits (59), Expect = 9.4, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 23/43 (53%), Gaps = 5/43 (11%) Query: 1 MVHNKVTIIGSGPAAHTAAIY-----LARAEIKPILYEGMMAN 38 M H V ++G+GP + AAI L+ A ++P + G+ N Sbjct: 3 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCLN 45 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3D8X-A nrPDB 442 e-124 5W4C-A nrPDB 409 e-114 6BPY-A nrPDB 392 e-110 4CBQ-A nrPDB 383 e-107 1VDC-A nrPDB 376 e-105 6BWT-A nrPDB 368 e-102 5U63-A nrPDB 365 e-101 2WHD-A nrPDB 361 e-100 5USX-A nrPDB 358 2e-99 5UTH-A nrPDB 353 8e-98 1F6M-A nrPDB 353 8e-98 2A87-A nrPDB 351 2e-97 2Q7V-A nrPDB 333 8e-92 4JNQ-A nrPDB 330 4e-91 5UWY-A nrPDB 328 2e-90 5MJK-A nrPDB 326 1e-89 3ISH-A nrPDB 325 1e-89 4GCM-A nrPDB 320 7e-88 5M5J-A nrPDB 304 2e-83 3F8P-A nrPDB 293 5e-80 4ZN0-A nrPDB 291 2e-79 3R9U-A nrPDB 290 6e-79 4YKF-A nrPDB 259 1e-69 1FL2-A nrPDB 251 3e-67 3LZX-A nrPDB 234 4e-62 2ZBW-A nrPDB 234 5e-62 6GAS-A nrPDB 231 2e-61 5XHU-A nrPDB 229 1e-60 5YGQ-A nrPDB 226 8e-60 5JFC-L nrPDB 216 1e-56 4YRY-B nrPDB 213 1e-55 6GAR-A nrPDB 210 4e-55 3AB1-A nrPDB 210 7e-55 5VJ7-A nrPDB 200 5e-52 4FK1-A nrPDB 186 9e-48 2BC1-A nrPDB 154 4e-38 3CGD-A nrPDB 154 5e-38 5U1O-A nrPDB 153 7e-38 3Q6J-A nrPDB 152 2e-37 3OC4-A nrPDB 150 1e-36 1YQZ-A nrPDB 149 2e-36 5VDN-A nrPDB 144 5e-35 2R9Z-A nrPDB 138 2e-33 2X8H-A nrPDB 132 2e-31 6DU7-A nrPDB 131 4e-31 5V36-A nrPDB 131 5e-31 2AAQ-A nrPDB 130 9e-31 4EMJ-A nrPDB 126 1e-29 5TR3-A nrPDB 125 4e-29 1ZK7-A nrPDB 116 2e-26 2CVJ-A nrPDB 89 2e-18 Sequences not found previously or not previously below threshold: 5TWC-A nrPDB 163 8e-41 6N7F-A nrPDB 138 3e-33 1ZDL-A nrPDB 134 4e-32 4LA1-A nrPDB 132 2e-31 1GEU-A nrPDB 131 5e-31 4KPR-E nrPDB 122 2e-28 4NTC-A nrPDB 122 2e-28 2NVK-X nrPDB 122 3e-28 5U8W-A nrPDB 120 6e-28 1NHQ-A nrPDB 119 1e-27 6AON-A nrPDB 119 2e-27 3LAD-A nrPDB 116 1e-26 4YWO-A nrPDB 115 3e-26 2CFY-A nrPDB 114 4e-26 2YQU-A nrPDB 113 8e-26 6B4O-A nrPDB 113 1e-25 2EQ6-A nrPDB 113 1e-25 5ER0-A nrPDB 113 1e-25 3URH-A nrPDB 112 2e-25 1EBD-A nrPDB 112 2e-25 5X1Y-B nrPDB 110 9e-25 6BZ0-A nrPDB 110 1e-24 2CDU-A nrPDB 110 1e-24 5J5Z-A nrPDB 108 3e-24 5W1J-A nrPDB 108 5e-24 4JDR-A nrPDB 106 8e-24 2WOV-A nrPDB 106 1e-23 3ICS-A nrPDB 105 2e-23 3IWA-A nrPDB 102 2e-22 6CMZ-A nrPDB 102 2e-22 1ONF-A nrPDB 101 4e-22 2HQM-A nrPDB 100 6e-22 1DXL-A nrPDB 100 7e-22 4DNA-A nrPDB 100 2e-21 5JCN-A nrPDB 99 2e-21 1FEC-A nrPDB 99 3e-21 3LXD-A nrPDB 98 4e-21 3O0H-A nrPDB 97 7e-21 3IC9-A nrPDB 97 1e-20 2QAE-A nrPDB 97 1e-20 2YAU-A nrPDB 95 3e-20 4NEW-A nrPDB 95 3e-20 4B1B-A nrPDB 95 4e-20 3FG2-P nrPDB 92 3e-19 2VDC-G nrPDB 90 9e-19 1Q1R-A nrPDB 90 9e-19 3II4-A nrPDB 90 1e-18 3NTA-A nrPDB 89 2e-18 1LVL-A nrPDB 88 5e-18 2YVG-A nrPDB 84 7e-17 1V59-A nrPDB 82 3e-16 3L8K-A nrPDB 82 3e-16 1XDI-A nrPDB 82 4e-16 5NMX-A nrPDB 81 7e-16 4FX9-A nrPDB 81 7e-16 2V3B-A nrPDB 80 9e-16 4USR-A nrPDB 80 2e-15 1XHC-A nrPDB 80 2e-15 4C5O-A nrPDB 75 6e-14 3KLJ-A nrPDB 69 2e-12 3UP5-A nrPDB 66 2e-11 1OJT-A nrPDB 64 1e-10 1PS9-A nrPDB 62 3e-10 5U25-A nrPDB 62 4e-10 2TMD-A nrPDB 60 1e-09 5J7X-A nrPDB 58 4e-09 4OVI-A nrPDB 58 7e-09 6A37-A nrPDB 57 2e-08 1LQU-A nrPDB 55 3e-08 6HNS-A nrPDB 55 3e-08 3K30-A nrPDB 55 4e-08 6ER9-A nrPDB 55 4e-08 5JWC-A nrPDB 55 5e-08 5KVH-A nrPDB 54 7e-08 4RG3-A nrPDB 54 7e-08 6JDK-A nrPDB 53 2e-07 4AP1-A nrPDB 51 6e-07 2GV8-A nrPDB 50 2e-06 2XVH-A nrPDB 49 2e-06 5GSN-A nrPDB 48 6e-06 3H8L-A nrPDB 47 8e-06 5MIU-A nrPDB 47 1e-05 3T14-A nrPDB 44 7e-05 4Y4N-A nrPDB 43 2e-04 4Y4M-A nrPDB 43 2e-04 1Y56-A nrPDB 42 3e-04 3NK2-X nrPDB 42 5e-04 3RHA-A nrPDB 42 5e-04 4TLZ-A nrPDB 42 5e-04 4B68-A nrPDB 42 5e-04 3LOV-A nrPDB 41 7e-04 4G74-A nrPDB 41 8e-04 2UZZ-A nrPDB 40 0.001 3ATQ-A nrPDB 40 0.001 3WE0-A nrPDB 40 0.001 2JB2-A nrPDB 40 0.001 1F8S-A nrPDB 40 0.001 1E1N-A nrPDB 40 0.001 4A6N-B nrPDB 40 0.002 1ZOV-A nrPDB 40 0.002 3ABT-A nrPDB 39 0.002 5L3D-A nrPDB 39 0.003 3CP8-A nrPDB 39 0.003 3HWR-A nrPDB 39 0.003 3KYB-A nrPDB 39 0.003 3FPZ-A nrPDB 39 0.003 3NIX-A nrPDB 39 0.003 2BXR-A nrPDB 38 0.005 3IHG-A nrPDB 38 0.005 2GAG-A nrPDB 38 0.005 4TXK-A nrPDB 38 0.006 2BRY-A nrPDB 38 0.006 2VVL-G nrPDB 38 0.006 1REO-A nrPDB 38 0.006 4MOP-A nrPDB 37 0.008 1NAA-A nrPDB 37 0.010 5CQF-A nrPDB 37 0.011 5MOG-A nrPDB 37 0.012 1C0L-A nrPDB 37 0.013 3BHF-A nrPDB 37 0.013 3JSK-A nrPDB 37 0.014 1VRQ-A nrPDB 37 0.015 5KXJ-A nrPDB 37 0.017 4IIN-A nrPDB 37 0.017 5XGV-A nrPDB 36 0.018 4Z2R-A nrPDB 36 0.029 4IV9-A nrPDB 36 0.030 5PGZ-A nrPDB 35 0.033 5NA1-A nrPDB 35 0.036 3S61-A nrPDB 35 0.037 1RP0-A nrPDB 35 0.038 1FOH-A nrPDB 35 0.039 6C6P-A nrPDB 35 0.040 3KVE-A nrPDB 35 0.043 2QA2-A nrPDB 35 0.044 5TUF-A nrPDB 35 0.053 2E5V-A nrPDB 35 0.053 2DKH-A nrPDB 35 0.058 5KOX-A nrPDB 35 0.065 5Z70-A nrPDB 35 0.067 4EIQ-A nrPDB 34 0.073 2CDC-A nrPDB 34 0.079 1O5W-A nrPDB 34 0.080 4Z25-A nrPDB 34 0.088 4K2X-A nrPDB 34 0.100 2GMH-A nrPDB 34 0.10 4CJX-A nrPDB 34 0.11 3TL2-A nrPDB 34 0.11 2IPC-A nrPDB 34 0.11 3I6D-A nrPDB 33 0.12 6DLL-A nrPDB 33 0.14 1SEZ-A nrPDB 33 0.16 1DOD-A nrPDB 33 0.16 6CR0-A nrPDB 33 0.17 6J0Z-C nrPDB 33 0.17 1KNR-A nrPDB 33 0.17 5XW0-A nrPDB 33 0.18 6BRD-A nrPDB 33 0.19 4Z44-A nrPDB 33 0.21 1FW8-A nrPDB 33 0.22 1QPG-A nrPDB 33 0.22 4X4J-A nrPDB 33 0.23 3RP7-A nrPDB 33 0.24 5X68-A nrPDB 33 0.24 2VOU-A nrPDB 33 0.25 3HN2-A nrPDB 33 0.25 3K96-A nrPDB 33 0.26 5XMJ-A nrPDB 32 0.26 6FEA-B nrPDB 32 0.28 4UIR-A nrPDB 32 0.29 3BI4-A nrPDB 32 0.35 3G5Q-A nrPDB 32 0.43 5EZ7-A nrPDB 32 0.43 1QP8-A nrPDB 31 0.47 5TUM-A nrPDB 31 0.52 5Y77-A nrPDB 31 0.53 3HDH-A nrPDB 31 0.53 5ZBC-A nrPDB 31 0.57 3LK7-A nrPDB 31 0.60 3UKH-A nrPDB 31 0.60 5X6R-A nrPDB 31 0.61 4EJ6-A nrPDB 31 0.61 3DFZ-A nrPDB 31 0.62 4ZCC-A nrPDB 31 0.64 1KSU-A nrPDB 31 0.67 4IA5-A nrPDB 31 0.68 1QO8-A nrPDB 31 0.68 3KKJ-A nrPDB 31 0.73 4K22-A nrPDB 31 0.82 1ZFN-A nrPDB 31 0.84 3H9U-A nrPDB 31 0.89 1F14-A nrPDB 31 0.90 6ETZ-A nrPDB 30 1.2 3IHM-A nrPDB 30 1.2 2VHY-A nrPDB 30 1.3 2BS2-A nrPDB 30 1.4 6ACQ-A nrPDB 30 1.4 6GAQ-A nrPDB 30 1.5 3K5P-A nrPDB 30 1.5 3L1R-A nrPDB 30 1.6 3ULE-B nrPDB 30 1.6 4DGK-A nrPDB 30 1.7 6H3G-A nrPDB 30 1.8 2IVE-A nrPDB 30 1.8 1WTH-A nrPDB 30 1.9 1GPJ-A nrPDB 30 2.1 4MIF-A nrPDB 30 2.1 1TQY-B nrPDB 29 2.2 6IGZ-6 nrPDB 29 2.2 1KYQ-A nrPDB 29 2.4 4R16-A nrPDB 29 2.5 3G1U-A nrPDB 29 2.5 1NP3-A nrPDB 29 2.5 4X3Q-A nrPDB 29 2.6 3K6J-A nrPDB 29 2.7 5AYV-A nrPDB 29 2.7 3ULK-A nrPDB 29 2.7 1PJS-A nrPDB 29 2.7 4A7P-A nrPDB 29 2.8 3OPQ-A nrPDB 29 2.8 2HJR-A nrPDB 29 2.9 3VPX-A nrPDB 29 2.9 1V9L-A nrPDB 29 2.9 4B2T-D nrPDB 29 2.9 5YLN-A nrPDB 29 3.1 5DT9-A nrPDB 29 3.2 2EBD-A nrPDB 29 3.3 1GUZ-A nrPDB 29 3.5 4OM8-A nrPDB 29 3.5 2ZXH-A nrPDB 29 3.5 5L46-A nrPDB 28 3.9 6NBK-A nrPDB 28 4.1 2DQ4-A nrPDB 28 4.5 5JXW-A nrPDB 28 4.6 4IVM-B nrPDB 28 4.6 3OZ2-A nrPDB 28 4.7 1UPS-A nrPDB 28 5.2 3IP1-A nrPDB 28 5.3 3BA1-A nrPDB 28 5.6 3UOG-A nrPDB 28 5.7 4G65-A nrPDB 28 5.7 2X19-B nrPDB 28 5.7 3WID-A nrPDB 28 5.8 3GG2-A nrPDB 28 5.9 6APH-A nrPDB 28 6.6 4OBV-D nrPDB 28 6.6 1VL1-A nrPDB 28 7.0 5YEQ-A nrPDB 28 7.3 9LDB-A nrPDB 28 7.4 2GAG-B nrPDB 28 7.6 6C55-A nrPDB 28 7.9 4P9S-A nrPDB 28 8.2 2CUL-A nrPDB 28 8.2 3G05-A nrPDB 27 8.4 6MO6-A nrPDB 27 8.4 3CP2-A nrPDB 27 8.4 6ACF-A nrPDB 27 8.6 3X0D-A nrPDB 27 8.6 6D9T-A nrPDB 27 8.8 3KYD-B nrPDB 27 9.0 3K8Z-A nrPDB 27 9.2 6DKT-A nrPDB 27 9.3 4XIY-A nrPDB 27 9.5 3AQ1-B nrPDB 27 9.5 3KYC-B nrPDB 27 9.6 1I8T-A nrPDB 27 9.6 2PA3-A nrPDB 27 9.7 3NEP-X nrPDB 27 9.8 1Y6J-A nrPDB 27 9.8 1GV0-A nrPDB 27 9.8 6IUM-B nrPDB 27 10.0 >3D8X-A nrPDB Length = 326 Score = 442 bits (1136), Expect = e-124, Method: Composition-based stats. Identities = 318/318 (100%), Positives = 318/318 (100%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG Sbjct: 9 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 68 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA Sbjct: 69 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 128 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF Sbjct: 129 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 188 Query: 182 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 241 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV Sbjct: 189 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 248 Query: 242 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA Sbjct: 249 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 308 Query: 302 GSGCMAALDAEKYLTSLE 319 GSGCMAALDAEKYLTSLE Sbjct: 309 GSGCMAALDAEKYLTSLE 326 >5W4C-A nrPDB Length = 371 Score = 409 bits (1051), Expect = e-114, Method: Composition-based stats. Identities = 224/319 (70%), Positives = 264/319 (82%), Gaps = 1/319 (0%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 +H+KV IIGSGP HTAAIYLARA ++P+LYEGM+ANG A GGQLTTTT++ENFPGFP+G Sbjct: 29 MHSKVVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLTTTTDVENFPGFPEG 88 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPV-TTDAIILATG 120 +TG+E+MD+ R QS +FGT+IITETV++VDLS +PFK WTE E+ T D IILATG Sbjct: 89 VTGTEMMDKFRAQSERFGTKIITETVARVDLSVRPFKYWTEGEEEEHEFMTADTIILATG 148 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ASAKR+ LPGEETYWQ GISACAVCDGAVPIFR KPLAVIGGGDSA EEA +LTKYGS V Sbjct: 149 ASAKRLFLPGEETYWQSGISACAVCDGAVPIFRQKPLAVIGGGDSAAEEATYLTKYGSHV 208 Query: 181 FMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLP 240 ++LVR+D LRAS IM KR + K+ +L+NTVA EAKGDG++L +L IKNTK E DLP Sbjct: 209 YVLVRRDELRASKIMAKRLTSHPKVTVLWNTVATEAKGDGEVLTSLTIKNTKTGETGDLP 268 Query: 241 VSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITS 300 V+GLFYAIGH PAT +V QV+ D GYIKTVPG+S TSV G FAAGDVQD KYRQAITS Sbjct: 269 VNGLFYAIGHEPATSLVKSQVELDSDGYIKTVPGTSQTSVHGVFAAGDVQDKKYRQAITS 328 Query: 301 AGSGCMAALDAEKYLTSLE 319 AGSGC+AAL+AE+ ++ E Sbjct: 329 AGSGCIAALEAERLISEEE 347 >6BPY-A nrPDB Length = 374 Score = 392 bits (1008), Expect = e-110, Method: Composition-based stats. Identities = 219/321 (68%), Positives = 260/321 (80%), Gaps = 6/321 (1%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 MVH KV IIGSGPAAHTAAIYL+RAE+KP+LYEGM+ANG AAGGQLTTTT+IENFPGFPD Sbjct: 2 MVHTKVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFPD 61 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEP---VTTDAIIL 117 G+ G+ELM+ MR+QS +FGTE+ITET+S+VDLSSKPFKLWTE+N+ + T DA+I+ Sbjct: 62 GIGGAELMENMRKQSIRFGTEVITETISRVDLSSKPFKLWTEWNDGPDKEPACTADAVII 121 Query: 118 ATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 ATGA+A+R++LPGEETYWQ GISACAVCDGAVPIFRNKPL VIGGGDSA EEA FL KYG Sbjct: 122 ATGANARRLNLPGEETYWQNGISACAVCDGAVPIFRNKPLYVIGGGDSAAEEAMFLAKYG 181 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGD---GKLLNALRIKNTKKN 234 S V +LVR+D LRAS M KR + K+ + +NTVA E G+ L+ LRIKNT Sbjct: 182 SSVTVLVRRDKLRASKAMAKRLLAHPKVTVRFNTVATEVLGEKKPNGLMTHLRIKNTVTG 241 Query: 235 EETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 EE + +GLFYA+GH PAT +V GQ+D DE GYI T PG+S TS G FA GDVQD +Y Sbjct: 242 EEEIVDANGLFYAVGHDPATALVKGQIDLDEDGYIITKPGTSYTSREGVFACGDVQDKRY 301 Query: 295 RQAITSAGSGCMAALDAEKYL 315 RQAITSAGSGC+AAL+AEK++ Sbjct: 302 RQAITSAGSGCIAALEAEKFI 322 >4CBQ-A nrPDB Length = 314 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 191/314 (60%), Positives = 237/314 (75%), Gaps = 5/314 (1%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 + V IIGSGPAAHTAAIYL R+ +KP++YEG MA G+AAGGQLTTTT IENFPGFP+G+ Sbjct: 5 HDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGFMAGGVAAGGQLTTTTIIENFPGFPNGID 64 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 G+ELM MR QS K+GT IITET+ VD S++PFKL+T E+ + V T ++I+ATGA+A Sbjct: 65 GNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFKLFT---EEGKEVLTKSVIIATGATA 121 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 KRMH+PGE+ YWQ G+SACA+CDGAVPIFRNK L V+GGGD+A EEA LTKYGSKV +L Sbjct: 122 KRMHVPGEDKYWQNGVSACAICDGAVPIFRNKVLMVVGGGDAAMEEALHLTKYGSKVIIL 181 Query: 184 VRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 R+D RAS MQ+R + KIE+++N+ +E +GDG LLN +I N E +PV+G Sbjct: 182 HRRDAFRASKTMQERVLNHPKIEVIWNSELVELEGDGDLLNGAKIHNLVSGEYKVVPVAG 241 Query: 244 LFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGS 303 LFYAIGH+P +K + GQV T + GYI T TSV G FA GDV D YRQAI +AGS Sbjct: 242 LFYAIGHSPNSKFLGGQVKTADDGYILT--EGPKTSVDGVFACGDVCDRVYRQAIVAAGS 299 Query: 304 GCMAALDAEKYLTS 317 GCMAAL EK+L + Sbjct: 300 GCMAALSCEKWLQT 313 >1VDC-A nrPDB Length = 333 Score = 376 bits (965), Expect = e-105, Method: Composition-based stats. Identities = 201/321 (62%), Positives = 249/321 (77%), Gaps = 10/321 (3%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 ++ I+GSGPAAHTAAIY ARAE+KP+L+EG MAN IA GGQLTTTT++ENFPGFP+G+ Sbjct: 9 TRLCIVGSGPAAHTAAIYAARAELKPLLFEGWMANDIAPGGQLTTTTDVENFPGFPEGIL 68 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 G EL D+ R+QS +FGT I TETV+KVD SSKPFKL+T D++ + DA+ILA GA A Sbjct: 69 GVELTDKFRKQSERFGTTIFTETVTKVDFSSKPFKLFT----DSKAILADAVILAIGAVA 124 Query: 124 KRMHLPGEET----YWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK 179 KR+ G +W +GISACAVCDGA PIFRNKPLAVIGGGDSA EEA FLTKYGSK Sbjct: 125 KRLSFVGSGEVLGGFWNRGISACAVCDGAAPIFRNKPLAVIGGGDSAMEEANFLTKYGSK 184 Query: 180 VFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGK--LLNALRIKNTKKNEET 237 V+++ R+D RAS IMQ+RA N KI++++N+ +EA GDG+ +L L++KN + + Sbjct: 185 VYIIHRRDAFRASKIMQQRALSNPKIDVIWNSSVVEAYGDGERDVLGGLKVKNVVTGDVS 244 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQA 297 DL VSGLF+AIGH PATK + G V+ D GY+ T PG++ TSVPG FAAGDVQD KYRQA Sbjct: 245 DLKVSGLFFAIGHEPATKFLDGGVELDSDGYVVTKPGTTQTSVPGVFAAGDVQDKKYRQA 304 Query: 298 ITSAGSGCMAALDAEKYLTSL 318 IT+AG+GCMAALDAE YL + Sbjct: 305 ITAAGTGCMAALDAEHYLQEI 325 >6BWT-A nrPDB Length = 319 Score = 368 bits (946), Expect = e-102, Method: Composition-based stats. Identities = 158/324 (48%), Positives = 222/324 (68%), Gaps = 19/324 (5%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H+K+ I+GSGPA +TAAIY ARA +KP++ GM GGQLTTTT++ N+PG PDG+ Sbjct: 7 HHKLIILGSGPAGYTAAIYAARANLKPVIITGM-----QPGGQLTTTTDVYNWPGEPDGI 61 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 G ELM+++++Q+ +F T+I+ +T++ VDL +KPFKL + E T D +I+ATGA+ Sbjct: 62 MGPELMEKLQKQAERFDTQIVYDTINAVDLQNKPFKLV----GEVEQYTCDTLIIATGAT 117 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 AK + L EE + KG+SACA CDG ++NK +AV+GGG++A EEA FL+ V + Sbjct: 118 AKYLGLESEEKFMGKGVSACATCDGF--FYKNKDVAVVGGGNTAVEEALFLSNIAKSVTL 175 Query: 183 LVRKDHLRASTIMQKRAEK---NEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDL 239 + R+D LR+ I+ + + + I I++NT E GD +NALRIKN K NEE+ + Sbjct: 176 IHRRDTLRSEKILIDKLMEKAQHGNINIIWNTTLEEVLGDDMGVNALRIKNIKTNEESQM 235 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVP----GSSLTSVPGFFAAGDVQDSKYR 295 V+G+F AIGHTP T I AGQ++ E GYIK ++ T++ G FAAGDV D Y+ Sbjct: 236 GVAGVFIAIGHTPNTSIFAGQLEM-ENGYIKVKSGLAGDATQTNIKGVFAAGDVADHVYK 294 Query: 296 QAITSAGSGCMAALDAEKYLTSLE 319 QA+TSAG+GCMAALDAEKYL +L+ Sbjct: 295 QAVTSAGTGCMAALDAEKYLDNLD 318 >5U63-A nrPDB Length = 321 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 161/326 (49%), Positives = 212/326 (65%), Gaps = 19/326 (5%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 + H K+ I+GSGPA +TAAIY ARA +KP+L G+ GGQLTTT EIEN+PG + Sbjct: 7 IKHAKLLILGSGPAGYTAAIYAARANLKPVLVTGLQQ-----GGQLTTTDEIENWPGDFE 61 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 TGS LM RM + + KF TEI+ + +++VDLSS+PFKL+ D + T DA+I+ATG Sbjct: 62 MTTGSGLMQRMLQHAEKFETEIVFDHINRVDLSSRPFKLF----GDVQNFTCDALIIATG 117 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ASA+ + LP EE Y +G+SACA CDG +RNKP+ VIGGG++A EEA +L S V Sbjct: 118 ASARYIGLPSEENYKGRGVSACATCDGF--FYRNKPVGVIGGGNTAVEEALYLANIASTV 175 Query: 181 FMLVRKDHLRASTIMQKRAEK---NEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEET 237 ++ R+D RA I+ R K KI + + E GD + LR+ NTK E+ Sbjct: 176 HLIHRRDSFRAEKILIDRLYKKVEEGKIVLHTDRTLDEVLGDNMGVTGLRLANTKTGEKE 235 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSK 293 +L + GLF AIGH+P T+I GQ++ + GYI G ++ TSV G FAAGDV D Sbjct: 236 ELKLDGLFVAIGHSPNTEIFQGQLELN-NGYIVVKSGLDGNATATSVEGVFAAGDVMDHN 294 Query: 294 YRQAITSAGSGCMAALDAEKYLTSLE 319 YRQAITSAG+GCMAALDAE+YL + E Sbjct: 295 YRQAITSAGTGCMAALDAERYLDAQE 320 >2WHD-A nrPDB Length = 351 Score = 361 bits (926), Expect = e-100, Method: Composition-based stats. Identities = 189/319 (59%), Positives = 242/319 (75%), Gaps = 6/319 (1%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 + +V IIGSGPAAHTAAIY ARAE+KP+L+EG MAN IAAGGQLTTTT++ENFPGFP G Sbjct: 29 LRTRVCIIGSGPAAHTAAIYAARAELKPVLFEGWMANDIAAGGQLTTTTDVENFPGFPTG 88 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 + G +LMD R QS +FGT I++ETV++VD S++PF++ D+ V D +++ATGA Sbjct: 89 IMGIDLMDNCRAQSVRFGTNILSETVTEVDFSARPFRV----TSDSTTVLADTVVVATGA 144 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 A+R++ G +TYW +GISACAVCDGA PIFRNKP+AVIGGGDSA EE FLTKYGS+V+ Sbjct: 145 VARRLYFSGSDTYWNRGISACAVCDGAAPIFRNKPIAVIGGGDSAMEEGNFLTKYGSQVY 204 Query: 182 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE--AKGDGKLLNALRIKNTKKNEETDL 239 ++ R++ RAS IMQ RA N KI++++++ +E G L +++KN E +DL Sbjct: 205 IIHRRNTFRASKIMQARALSNPKIQVVWDSEVVEAYGGAGGGPLAGVKVKNLVTGEVSDL 264 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 VSGLF+AIGH PATK + GQ++ GY+ T PGS+ TSV G FAAGDVQD KYRQAIT Sbjct: 265 QVSGLFFAIGHEPATKFLNGQLELHADGYVATKPGSTHTSVEGVFAAGDVQDKKYRQAIT 324 Query: 300 SAGSGCMAALDAEKYLTSL 318 +AGSGCMAALDAE YL + Sbjct: 325 AAGSGCMAALDAEHYLQEV 343 >5USX-A nrPDB Length = 319 Score = 358 bits (918), Expect = 2e-99, Method: Composition-based stats. Identities = 156/325 (48%), Positives = 213/325 (65%), Gaps = 19/325 (5%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 M H+K+ I+GSGPA +TAA+Y ARA + P+L GM GGQLTTTTE+EN+PG P+ Sbjct: 4 MKHSKLLILGSGPAGYTAAVYAARANLNPVLITGMQQ-----GGQLTTTTEVENWPGDPE 58 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 GLTG LMDRM+E + +F TEII + +++VD S++PF L DA + DA+I++TG Sbjct: 59 GLTGPGLMDRMKEHAERFETEIIFDHINEVDFSTRPFVL----KGDAASYSCDALIISTG 114 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ASAK + L EE + +G+SACA CDG +RN+ +AV+GGG++A EEA +L+ ++V Sbjct: 115 ASAKYLGLESEEAFKGRGVSACATCDGF--FYRNQKVAVVGGGNTAVEEALYLSNIAAEV 172 Query: 181 FMLVRKDHLRASTIMQKRAE---KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEET 237 ++ R+D RA I+ R +N I + + V E GD + +R+K+ K Sbjct: 173 HLIHRRDSFRAEKILINRLMDKVQNGNIVLHTDRVLDEVLGDEMGVTGVRLKDVKTGGTE 232 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSK 293 +L V G F AIGH+P T+I GQ+D + GYI G ++ TSV G FAAGDV D Sbjct: 233 ELDVMGAFIAIGHSPNTQIFQGQLDM-KDGYILVKSGLEGNATQTSVEGIFAAGDVMDHN 291 Query: 294 YRQAITSAGSGCMAALDAEKYLTSL 318 YRQAITSAG+GCMAALDAE+YL SL Sbjct: 292 YRQAITSAGTGCMAALDAERYLDSL 316 >5UTH-A nrPDB Length = 319 Score = 353 bits (905), Expect = 8e-98, Method: Composition-based stats. Identities = 151/316 (47%), Positives = 211/316 (66%), Gaps = 12/316 (3%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 + V IIGSGPA +TAAIY ARA++KP+++E G GG L TTTE+EN+PGF +G+T Sbjct: 16 HDVIIIGSGPAGYTAAIYAARAQLKPLVFE-----GTQFGGALMTTTEVENYPGFREGIT 70 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 G ELMD+MREQ+ +FG ++ E V V L P K +E + A+ILA GA+A Sbjct: 71 GPELMDQMREQALRFGADLRMEDVDAVQLEG-PVKTVVVGDETHQ---ARAVILAMGAAA 126 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 + + +PGEE G+S CA CDG FR++ + V+GGGDSA EEA FLT++ V ++ Sbjct: 127 RHLGVPGEEALTGMGVSTCATCDGF--FFRDQDIVVVGGGDSAMEEATFLTRFARSVTLI 184 Query: 184 VRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 R+D RAS IM +RA NEKI L NT + +GD K + +R+++T EE+ L V+G Sbjct: 185 HRRDEFRASKIMLERARANEKITFLTNTEITQIEGDPK-VTGVRLRDTVTGEESKLDVTG 243 Query: 244 LFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGS 303 +F AIGH P +++V GQV+ D+ GY+K ++ TS+ G FAAGD+ D YRQAIT+AGS Sbjct: 244 VFVAIGHDPRSELVRGQVELDDEGYVKVQGRTTYTSLDGVFAAGDLVDHTYRQAITAAGS 303 Query: 304 GCMAALDAEKYLTSLE 319 GC A++DAE++L + Sbjct: 304 GCAASIDAERWLAEQD 319 >1F6M-A nrPDB Length = 320 Score = 353 bits (905), Expect = 8e-98, Method: Composition-based stats. Identities = 160/325 (49%), Positives = 217/325 (66%), Gaps = 20/325 (6%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 H+K+ I+GSGPA +TAA+Y ARA ++P+L GM GGQLTTTTE+EN+PG P+ Sbjct: 4 KHSKLLILGSGPAGYTAAVYAARANLQPVLITGMEK-----GGQLTTTTEVENWPGDPND 58 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 LTG LM+RM E +TKF TEII + ++KVDL ++PF+L N D T DA+I+ATGA Sbjct: 59 LTGPLLMERMHEHATKFETEIIFDHINKVDLQNRPFRL----NGDNGEYTCDALIIATGA 114 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 SA+ + LP EE + +G+SA A CDG +RN+ +AVIGGG++A EEA +L+ S+V Sbjct: 115 SARYLGLPSEEAFKGRGVSASATCDGF--FYRNQKVAVIGGGNTAVEEALYLSNIASEVH 172 Query: 182 MLVRKDHLRASTIMQKRAE---KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNE-ET 237 ++ R+D RA I+ KR +N I + N E GD + +R+++T+ ++ Sbjct: 173 LIHRRDGFRAEKILIKRLMDKVENGNIILHTNRTLEEVTGDQMGVTGVRLRDTQNSDNIE 232 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG----SSLTSVPGFFAAGDVQDSK 293 L V+GLF AIGH+P T I GQ++ E GYIK G ++ TS+PG FAAGDV D Sbjct: 233 SLDVAGLFVAIGHSPNTAIFEGQLEL-ENGYIKVQSGIHGNATQTSIPGVFAAGDVMDHI 291 Query: 294 YRQAITSAGSGCMAALDAEKYLTSL 318 YRQAITSAG+GCMAALDAE+YL L Sbjct: 292 YRQAITSAGTGCMAALDAERYLDGL 316 >2A87-A nrPDB Length = 335 Score = 351 bits (901), Expect = 2e-97, Method: Composition-based stats. Identities = 144/313 (46%), Positives = 202/313 (64%), Gaps = 11/313 (3%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V +IGSGPA +TAA+Y ARA++ P+++E G + GG L TTT++EN+PGF +G+TG Sbjct: 16 DVIVIGSGPAGYTAALYAARAQLAPLVFE-----GTSFGGALMTTTDVENYPGFRNGITG 70 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 ELMD MREQ+ +FG ++ E V V L L + D + A+ILA GA+A+ Sbjct: 71 PELMDEMREQALRFGADLRMEDVESVSLHG---PLKSVVTADGQTHRARAVILAMGAAAR 127 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + +PGE+ +G+S+CA CDG FR++ +AVIGGGDSA EEA FLT++ V ++ Sbjct: 128 YLQVPGEQELLGRGVSSCATCDGF--FFRDQDIAVIGGGDSAMEEATFLTRFARSVTLVH 185 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 R+D RAS IM RA N+KI L N + GD + LR+++T ET LPV+G+ Sbjct: 186 RRDEFRASKIMLDRARNNDKIRFLTNHTVVAVDGD-TTVTGLRVRDTNTGAETTLPVTGV 244 Query: 245 FYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 F AIGH P + +V +D D GY+ ++ TS+PG FAAGD+ D YRQA+T+AGSG Sbjct: 245 FVAIGHEPRSGLVREAIDVDPDGYVLVQGRTTSTSLPGVFAAGDLVDRTYRQAVTAAGSG 304 Query: 305 CMAALDAEKYLTS 317 C AA+DAE++L Sbjct: 305 CAAAIDAERWLAE 317 >2Q7V-A nrPDB Length = 325 Score = 333 bits (853), Expect = 8e-92, Method: Composition-based stats. Identities = 126/317 (39%), Positives = 184/317 (58%), Gaps = 13/317 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V IIG GPA TAAIY RA++ ++ E M GGQ+ + E+ENFPGFP+ + G Sbjct: 10 DVVIIGGGPAGLTAAIYTGRAQLSTLILEKGM-----PGGQIAWSEEVENFPGFPEPIAG 64 Query: 65 SELMDRMREQSTKFGTEIITETVSKV--DLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 EL RM +Q+ KFG ++ + V V D +S P+ A+ILATGA Sbjct: 65 MELAQRMHQQAEKFGAKVEMDEVQGVQHDATSHPYPFTVRGYNG--EYRAKAVILATGAD 122 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 +++ +PGE+ +W KG+S CA CDG ++ K + VIGGGD+A EE FLTK+ +V + Sbjct: 123 PRKLGIPGEDNFWGKGVSTCATCDGF--FYKGKKVVVIGGGDAAVEEGMFLTKFADEVTV 180 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS 242 + R+D LRA+ + Q RA N K++ +++T E +G ++ ++++N K E ++L Sbjct: 181 IHRRDTLRANKVAQARAFANPKMKFIWDTAVEEIQG-ADSVSGVKLRNLKTGEVSELATD 239 Query: 243 GLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAG 302 G+F IGH P T V V + GY+ V T++P FAAGDV D YRQ TS G Sbjct: 240 GVFIFIGHVPNTAFVKDTVSLRDDGYV-DVRDEIYTNIPMLFAAGDVSDYIYRQLATSVG 298 Query: 303 SGCMAALDAEKYLTSLE 319 +G AA+ E+ L +LE Sbjct: 299 AGTRAAMMTERQLAALE 315 >4JNQ-A nrPDB Length = 345 Score = 330 bits (847), Expect = 4e-91, Method: Composition-based stats. Identities = 132/323 (40%), Positives = 196/323 (60%), Gaps = 16/323 (4%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 H V +IGSGPA +TAAIY ARA +KP++ G+ GGQL TT++EN+PG+ + + Sbjct: 26 HAPVIVIGSGPAGYTAAIYAARAMLKPVVIAGLQQ-----GGQLMITTDVENYPGYAEPV 80 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 G +M++M Q+ G +I+ + +++V+ + +PF+L + T DA+I+ATGA Sbjct: 81 QGPWMMEQMARQAENVGAQIVHDIITEVETTVRPFRL---KGDSGTIYTCDALIIATGAQ 137 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 AK + L E+T+ G+SACA CDG +R K + V+GGG++A EEA +L+ V + Sbjct: 138 AKWLGLESEQTFMGGGVSACATCDGF--FYRGKDVVVVGGGNTAVEEALYLSHIAKSVTI 195 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGD------GKLLNALRIKNTKKNEE 236 + R+D RA IMQ R E + +++N+V E G G + +R+KN E Sbjct: 196 VHRRDGFRAEKIMQDRLLSRENVSVVWNSVIDEILGTEARPPMGATVTGVRLKNIVTGET 255 Query: 237 TDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQ 296 + G+F AIGH PA + G++ GY+ T P S+ T VPG FAAGDV D YRQ Sbjct: 256 QERATHGVFIAIGHAPAVSLFEGKLKQKPNGYLWTAPDSTATDVPGIFAAGDVTDDIYRQ 315 Query: 297 AITSAGSGCMAALDAEKYLTSLE 319 A+T+AG GCMAAL+AE++L + E Sbjct: 316 AVTAAGMGCMAALEAERWLAAQE 338 >5UWY-A nrPDB Length = 308 Score = 328 bits (841), Expect = 2e-90, Method: Composition-based stats. Identities = 123/314 (39%), Positives = 175/314 (55%), Gaps = 13/314 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 IIGSGPA TAA+Y AR+ + + E A GGQ+ T +IEN+PG+ D ++G Sbjct: 6 DTLIIGSGPAGMTAALYAARSNLSVAIIEQG-----APGGQMNNTFDIENYPGY-DHISG 59 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 EL +M E KF E I V K++ EDA +I+ATGA + Sbjct: 60 PELAMKMYEPLEKFNVENIYGIVQKIENFGD---YKCVLTEDAS-YEAKTVIIATGAKYR 115 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + +PGEE Y +G+S CAVCDGA FR++ L V+GGGDSA EEA +LT++ KV ++ Sbjct: 116 VLGVPGEEYYTSRGVSYCAVCDGA--FFRDQDLLVVGGGDSAVEEAIYLTQFAKKVTVVH 173 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 R+D LRA I+Q RA N+K++ ++++V E +G+ ++ + I+N K + TD G+ Sbjct: 174 RRDQLRAQKILQDRAFANDKVDFIWDSVVKEIQGNDIKVSNVLIENVKTGQVTDHAFGGV 233 Query: 245 FYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 F +G P T +V TD G+I T TS+PG FA GDV+ RQ T+ G G Sbjct: 234 FIYVGMNPVTGMVKDLEITDSEGWIIT-DDHMRTSIPGIFAIGDVRQKDLRQITTAVGDG 292 Query: 305 CMAALDAEKYLTSL 318 +A YL S Sbjct: 293 AIAGQGVYHYLESF 306 >5MJK-A nrPDB Length = 327 Score = 326 bits (835), Expect = 1e-89, Method: Composition-based stats. Identities = 133/317 (41%), Positives = 190/317 (59%), Gaps = 13/317 (4%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 V IIGSGPA TAA+Y AR+E+K +L E + GGQ+ T EIEN+PG+ + Sbjct: 23 KKYDVVIIGSGPAGMTAAMYTARSEMKTLLLERGV-----PGGQMNNTAEIENYPGY-ET 76 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 + G EL +M E G E V+ ++ K+ TE +E T +II+ATGA Sbjct: 77 IMGPELSMKMAEPLEGLGVENAYGFVTGIEDHGDYKKIITEDDE----FITKSIIIATGA 132 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 + +++ +PGEE Y +G+S CAVCDGA FRN+ + VIGGGDSA EEA +LT++G V Sbjct: 133 NHRKLEIPGEEEYGARGVSYCAVCDGA--FFRNQEILVIGGGDSAVEEALYLTRFGQSVT 190 Query: 182 MLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 241 ++ R+D LRA I+Q+RA K EKI ++++V +E KGD K + ++ KN K E T+ Sbjct: 191 IMHRRDKLRAQEIIQQRAFKEEKINFIWDSVPMEIKGDDKKIQSVVYKNVKTGEVTEKAF 250 Query: 242 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 G+F +G P + V+ TDEAG+I T T++PG FA GDV+ +RQ T+ Sbjct: 251 GGIFIYVGLDPVAEFVSDLGITDEAGWIIT-DDHMRTNIPGIFAVGDVRQKDFRQITTAV 309 Query: 302 GSGCMAALDAEKYLTSL 318 G G AA +A K++ L Sbjct: 310 GDGAQAAQEAYKFVVEL 326 >3ISH-A nrPDB Length = 311 Score = 325 bits (834), Expect = 1e-89, Method: Composition-based stats. Identities = 117/320 (36%), Positives = 171/320 (53%), Gaps = 17/320 (5%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIK-PILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 IIG GPA +A +Y R +K +L+E M GGQ+T ++EIEN+PG + + Sbjct: 2 IDCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGM-----PGGQITGSSEIENYPGVKEVV 56 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 +G + M +EQ +FG + V +V F + ED + ++I+ATG S Sbjct: 57 SGLDFMQPWQEQCFRFGLKHEMTAVQRVSKKDSHFVILA---EDGKTFEAKSVIIATGGS 113 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 KR + GE YW KG+S CA CDG ++NK +AV+GGGD+A EEA +L KV++ Sbjct: 114 PKRTGIKGESEYWGKGVSTCATCDGF--FYKNKEVAVLGGGDTAVEEAIYLANICKKVYL 171 Query: 183 LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS 242 + R+D R + I + A+ N+KIE L V E KGD +++L IKNT NE+ +L V Sbjct: 172 IHRRDGFRCAPITLEHAKNNDKIEFLTPYVVEEIKGDASGVSSLSIKNTATNEKRELVVP 231 Query: 243 GLFYAIGHTPATKIVAGQ-----VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQA 297 G F +G+ ++ + DE G I V S T+V G FAAGD++ +Q Sbjct: 232 GFFIFVGYDVNNAVLKQEDNSMLCKCDEYGSI-VVDFSMKTNVQGLFAAGDIRIFAPKQV 290 Query: 298 ITSAGSGCMAALDAEKYLTS 317 + +A G AAL YL Sbjct: 291 VCAASDGATAALSVISYLEH 310 >4GCM-A nrPDB Length = 312 Score = 320 bits (819), Expect = 7e-88, Method: Composition-based stats. Identities = 124/314 (39%), Positives = 178/314 (56%), Gaps = 13/314 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 + IIG+GPA TAA+Y +RA +K ++ E + GGQ+ T E+ENFPGF + +TG Sbjct: 8 DIAIIGAGPAGMTAAVYASRANLKTVMIERGI-----PGGQMANTEEVENFPGF-EMITG 61 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 +L +M E + KFG + V+ + + N + +T A+I+ATGA K Sbjct: 62 PDLSTKMFEHAKKFGAVYQYGDIKSVEDKGE----YKVINFGNKELTAKAVIIATGAEYK 117 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 ++ +PGE+ +G+S CAVCDGA F+NK L VIGGGDSA EE FLTK+ KV ++ Sbjct: 118 KIGVPGEQELGGRGVSYCAVCDGA--FFKNKRLFVIGGGDSAVEEGTFLTKFADKVTIVH 175 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 R+D LRA I+Q RA KN+KI+ +++ + ++ + +TK E G+ Sbjct: 176 RRDELRAQRILQDRAFKNDKIDFIWSHTLKSINEKDGKVGSVTLTSTKDGSEETHEADGV 235 Query: 245 FYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 F IG P T T++ GYI T TSVPG FAAGDV+D RQ +T+ G G Sbjct: 236 FIYIGMKPLTAPFKDLGITNDVGYIVTKDD-MTTSVPGIFAAGDVRDKGLRQIVTATGDG 294 Query: 305 CMAALDAEKYLTSL 318 +AA A +Y+ L Sbjct: 295 SIAAQSAAEYIEHL 308 >5M5J-A nrPDB Length = 325 Score = 304 bits (780), Expect = 2e-83, Method: Composition-based stats. Identities = 137/309 (44%), Positives = 193/309 (62%), Gaps = 12/309 (3%) Query: 13 PAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSELMDRMR 72 PA TA IY +RA +K ++ GI Q+ TTT++ENFP + G LM+ ++ Sbjct: 27 PAGLTAGIYASRANLKTCVF-----VGIEHTSQMFTTTDVENFPSHT-AIKGPALMEAIQ 80 Query: 73 EQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEE 132 Q+ G E++ E V +D+SS+PFK+ + + E DA+I+ATGA+A+R+ GE+ Sbjct: 81 NQAEHCGAELLYEDVHSIDVSSRPFKIVHGY--ENETTLADALIIATGATARRLDCKGEK 138 Query: 133 TYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAS 192 YWQKG+SACAVCD A+ K + V+GGGD ACEEA +LTK +KV+M++R+D RAS Sbjct: 139 EYWQKGVSACAVCDSAMAT--GKEVVVVGGGDVACEEATYLTKIATKVYMVLRRDKFRAS 196 Query: 193 TIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP 252 M K+ + IEI+Y++ E KGDGK + ++ IKN K + L L++A+GH P Sbjct: 197 AAMVKKVMNEKLIEIIYDSAIDEIKGDGKCVTSVSIKNLKDGKTRTLNAGALYWAVGHDP 256 Query: 253 ATKIV-AGQVDTDEAGYIKTVPG-SSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALD 310 T + GQ++ DEAGYI + TSV G FAAGD D YRQA+ +AGSG AALD Sbjct: 257 QTSFLKKGQLEQDEAGYILLKDHPTQRTSVDGVFAAGDCCDHLYRQAVVAAGSGSKAALD 316 Query: 311 AEKYLTSLE 319 AE++L E Sbjct: 317 AERWLAMQE 325 >3F8P-A nrPDB Length = 323 Score = 293 bits (751), Expect = 5e-80, Method: Composition-based stats. Identities = 109/316 (34%), Positives = 177/316 (56%), Gaps = 17/316 (5%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V I+G GPAA+ AA+Y AR +K ++ G GGQLT ++++ G + + Sbjct: 17 DVIIVGLGPAAYGAALYSARYMLKTLVI------GETPGGQLTEAGIVDDYLGLIE-IQA 69 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 S+++ + K+ ++ + V K++ F + T+ + D++IL G + Sbjct: 70 SDMIKVFNKHIEKYEVPVLLDIVEKIENRGDEFVVKTKRKGE---FKADSVILGIGVKRR 126 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 ++ +PGE+ + +GIS C+VCD P+F+N+ +AVIGGGDSA E A+ L+ Y +KV+++ Sbjct: 127 KLGVPGEQEFAGRGISYCSVCDA--PLFKNRVVAVIGGGDSALEGAEILSSYSTKVYLIH 184 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 R+D +A I + +K +E + N+V E KGD K++ + ++N K E +L V+G+ Sbjct: 185 RRDTFKAQPIYVETVKKKPNVEFVLNSVVKEIKGD-KVVKQVVVENLKTGEIKELNVNGV 243 Query: 245 FYAIGHTPATKIVA-GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDS--KYRQAITSA 301 F IG P T ++TD GYIK V TSVPG FAAGD + +RQ IT+ Sbjct: 244 FIEIGFDPPTDFAKSNGIETDTNGYIK-VDEWMRTSVPGVFAAGDCTSAWLGFRQVITAV 302 Query: 302 GSGCMAALDAEKYLTS 317 G +AA A +Y+T Sbjct: 303 AQGAVAATSAYRYVTE 318 >4ZN0-A nrPDB Length = 311 Score = 291 bits (745), Expect = 2e-79, Method: Composition-based stats. Identities = 109/317 (34%), Positives = 172/317 (54%), Gaps = 18/317 (5%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 + IIG GPA TA IY R + ++ E GQ++ +EN+PGFP ++G Sbjct: 9 DLIIIGGGPAGLTAGIYAVRYGLDTLILE-----RNEISGQISMADIVENYPGFPS-ISG 62 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 ELM+R R + + G + V V D+ + A+I+ATGA+ K Sbjct: 63 LELMERFRTHAQEVGVKTTITEVLSVRSEG----TKKIITTDSGDLEAKAVIIATGANPK 118 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + +PGE+ KG+S CA+CDG P FRNK +AV+GGG+SA +A FL+K KV+++ Sbjct: 119 HLGVPGEKELISKGVSYCAICDG--PFFRNKIVAVVGGGNSAVTDALFLSKVAQKVYLVH 176 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALR---IKNTKKNEETDLPV 241 R+DHL+A+ ++Q R + IE++ N+ LE G + + + +++ E +L Sbjct: 177 RRDHLKAARVLQDRVDGTPNIELILNSHVLEIVGTREGIKKVEKIILEDVNSRETRELST 236 Query: 242 SGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSA 301 +G+F +G P T+ V V+ DE G+IKT TS G +AAGD +D+ Q +T+ Sbjct: 237 NGVFIYVGIHPNTEFVD--VEKDEGGFIKT-DRWMETSEKGIYAAGDCRDTPIWQLVTAV 293 Query: 302 GSGCMAALDAEKYLTSL 318 G +AA A +Y+ + Sbjct: 294 RDGAIAATAAYEYIEKI 310 >3R9U-A nrPDB Length = 315 Score = 290 bits (742), Expect = 6e-79, Method: Composition-based stats. Identities = 108/319 (33%), Positives = 171/319 (53%), Gaps = 15/319 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V IIG GPA +A +Y R +K ++ M GGQ+T+++EIEN+PG + G Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVV----MFEKGMPGGQITSSSEIENYPGVAQVMDG 61 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 M EQ +FG + V ++ +S +T E + A+I+ TG++ K Sbjct: 62 ISFMAPWSEQCMRFGLKHEMVGVEQILKNSD--GSFTIKLEGGKTELAKAVIVCTGSAPK 119 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + GE+ ++ KG+S CA CDG ++NK +AV+GGGD+A EEA +L SK++++ Sbjct: 120 KAGFKGEDEFFGKGVSTCATCDGF--FYKNKEVAVLGGGDTALEEALYLANICSKIYLIH 177 Query: 185 RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGL 244 R+D RA+ ++ +KNEKIE++ + E GD + +++K K DL V G+ Sbjct: 178 RRDEFRAAPSTVEKVKKNEKIELITSASVDEVYGDKMGVAGVKVK-LKDGSIRDLNVPGI 236 Query: 245 FYAIGHTPATKIVAGQ-----VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 F +G +I+ + +E G + +V TSV G FAAGD++ +Q I Sbjct: 237 FTFVGLNVRNEILKQDDSKFLCNMEEGGQV-SVDLKMQTSVAGLFAAGDLRKDAPKQVIC 295 Query: 300 SAGSGCMAALDAEKYLTSL 318 +AG G +AAL A Y+ SL Sbjct: 296 AAGDGAVAALSAMAYIESL 314 >4YKF-A nrPDB Length = 521 Score = 259 bits (661), Expect = 1e-69, Method: Composition-based stats. Identities = 100/312 (32%), Positives = 157/312 (50%), Gaps = 11/312 (3%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V I+GSGPA AAIY AR I+ L G GGQ+ T +IEN+ P G Sbjct: 214 DVLIVGSGPAGAAAAIYSARKGIRTGLM------GERFGGQILDTVDIENYISVPK-TEG 266 Query: 65 SELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +L ++ ++ ++I +++ SK+ ++ L + +II+ATGA Sbjct: 267 QKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKW 326 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 + M++PGE+ Y KG++ C CDG P+F+ K +AVIGGG+S E A L V +L Sbjct: 327 RNMNVPGEDQYRTKGVTYCPHCDG--PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLL 384 Query: 184 VRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 ++A ++Q + + ++I+ N E KGDG + L ++ + ++ ++G Sbjct: 385 EFAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAG 444 Query: 244 LFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGS 303 +F IG P T + G V+ + G I T+V G FAAGD Y+Q I + G Sbjct: 445 IFVQIGLLPNTNWLEGAVERNRMGEIII-DAKCETNVKGVFAAGDCTTVPYKQIIIATGE 503 Query: 304 GCMAALDAEKYL 315 G A+L A YL Sbjct: 504 GAKASLSAFDYL 515 >1FL2-A nrPDB Length = 310 Score = 251 bits (641), Expect = 3e-67, Method: Composition-based stats. Identities = 100/312 (32%), Positives = 157/312 (50%), Gaps = 11/312 (3%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V I+GSGPA AAIY AR I+ L G GGQ+ T +IEN+ P G Sbjct: 3 DVLIVGSGPAGAAAAIYSARKGIRTGLM------GERFGGQILDTVDIENYISVPK-TEG 55 Query: 65 SELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +L ++ ++ ++I +++ SK+ ++ L + +II+ATGA Sbjct: 56 QKLAGALKVHVDEYDVDVIDSQSASKLIPAAVEGGLHQIETASGAVLKARSIIVATGAKW 115 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 + M++PGE+ Y KG++ C CDG P+F+ K +AVIGGG+S E A L V +L Sbjct: 116 RNMNVPGEDQYRTKGVTYCPHCDG--PLFKGKRVAVIGGGNSGVEAAIDLAGIVEHVTLL 173 Query: 184 VRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 ++A ++Q + + ++I+ N E KGDG + L ++ + ++ ++G Sbjct: 174 EFAPEMKADQVLQDKLRSLKNVDIILNAQTTEVKGDGSKVVGLEYRDRVSGDIHNIELAG 233 Query: 244 LFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGS 303 +F IG P T + G V+ + G I T+V G FAAGD Y+Q I + G Sbjct: 234 IFVQIGLLPNTNWLEGAVERNRMGEIII-DAKCETNVKGVFAAGDCTTVPYKQIIIATGE 292 Query: 304 GCMAALDAEKYL 315 G A+L A YL Sbjct: 293 GAKASLSAFDYL 304 >3LZX-A nrPDB Length = 332 Score = 234 bits (597), Expect = 4e-62, Method: Composition-based stats. Identities = 80/322 (24%), Positives = 135/322 (41%), Gaps = 25/322 (7%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE---IENFPGFPDG 61 +TIIG GP A Y + + E + GGQL+ I + GFP Sbjct: 9 DITIIGGGPVGLFTAFYGGMRQASVKIIESLPQ----LGGQLSALYPEKYIYDVAGFPK- 63 Query: 62 LTGSELMDRMREQSTKFGTEIITET-VSKVDLSSK-PFKLWTEFNEDAEPVTTDAIILAT 119 + EL++ ++EQ KF I E V V+ + FKL T + E + +I+ Sbjct: 64 IRAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVT----NEETHYSKTVIITA 119 Query: 120 GAS---AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKY 176 G +++ L E Y K + + F + +A++GGGDSA + A L Sbjct: 120 GNGAFKPRKLELENAEQYEGKNLHY---FVDDLQKFAGRRVAILGGGDSAVDWALMLEPI 176 Query: 177 GSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEE 236 +V ++ R+D RA + K+ +L V E G+ K + L ++ K + + Sbjct: 177 AKEVSIIHRRDKFRAHEHSVENLHA-SKVNVLTPFVPAELIGEDK-IEQLVLEEVKGDRK 234 Query: 237 TDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQ 296 L + L G + + E I V + T++ GFFAAGD+ + + Sbjct: 235 EILEIDDLIVNYGFVSSLGPIKNWGLDIEKNSI-VVKSTMETNIEGFFAAGDICTYEGKV 293 Query: 297 AITSAGSG--CMAALDAEKYLT 316 + ++G G A +A+ Y+ Sbjct: 294 NLIASGFGEAPTAVNNAKAYMD 315 >2ZBW-A nrPDB Length = 335 Score = 234 bits (596), Expect = 5e-62, Method: Composition-based stats. Identities = 75/312 (24%), Positives = 127/312 (40%), Gaps = 23/312 (7%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE---IENFPGFP 59 H V I+G+GP A Y+ + + + GGQLT I + GFP Sbjct: 5 HTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPE----PGGQLTALYPEKYIYDVAGFP 60 Query: 60 DGLTGSELMDRMREQSTKFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 + +L+ + EQ F + E ++ FK+ T T A+I+A Sbjct: 61 K-VYAKDLVKGLVEQVAPFNPVYSLGERAETLEREGDLFKVTT---SQGNAYTAKAVIIA 116 Query: 119 TGAS---AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTK 175 G +R+ PGE + +G+ + F+ K + ++GGGDSA + A L Sbjct: 117 AGVGAFEPRRIGAPGEREFEGRGVYY---AVKSKAEFQGKRVLIVGGGDSAVDWALNLLD 173 Query: 176 YGSKVFMLVRKDHLRASTIMQK---RAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTK 232 ++ ++ R+ RA K +A + ++E+L +GD ++ A+ N + Sbjct: 174 TARRITLIHRRPQFRAHEASVKELMKAHEEGRLEVLTPYELRRVEGDERVRWAVVFHN-Q 232 Query: 233 KNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDS 292 EE L V + G+ +A E IK V + TS+PG +A GD+ Sbjct: 233 TQEELALEVDAVLILAGYITKLGPLANWGLALEKNKIK-VDTTMATSIPGVYACGDIVTY 291 Query: 293 KYRQAITSAGSG 304 + + G G Sbjct: 292 PGKLPLIVLGFG 303 >6GAS-A nrPDB Length = 331 Score = 231 bits (590), Expect = 2e-61, Method: Composition-based stats. Identities = 78/322 (24%), Positives = 133/322 (41%), Gaps = 25/322 (7%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE---IENFPGFPDG 61 +TIIG GP A Y + + E + GGQL+ I + GFP Sbjct: 11 DITIIGGGPTGLFTAFYGGMRQASVKIIESLPQ----LGGQLSALYPEKYIYDVAGFPK- 65 Query: 62 LTGSELMDRMREQSTKFGTEIITET-VSKVDLSSK-PFKLWTEFNEDAEPVTTDAIILAT 119 + EL+D ++EQ KF + E V ++ + FKL T + + + ++I+ Sbjct: 66 VRAQELVDNLKEQMKKFDPTVCLEEAVDTLEKQADGIFKLVT----NKQTHYSKSVIITA 121 Query: 120 GAS---AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKY 176 G +R+ L G Y +K + + F K + V GGGDSA + L Sbjct: 122 GNGAFQPRRLELEGTAKYEKKNLHY---FVDDMNKFAGKRVVVFGGGDSAVDWTMMLEPI 178 Query: 177 GSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEE 236 KV ++ R+D RA + N + E+ V +E GD K + + +++ K E+ Sbjct: 179 AEKVTIVHRRDKFRAHEHSVENLM-NSRAEVSTPYVPVELIGDDK-IEQVVLQHVKTEEK 236 Query: 237 TDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQ 296 + V + G + + + I V T++PG +AAGD+ + + Sbjct: 237 VIIDVDDVIVNYGFVSSLGPIKNWGLDIQKNSIL-VNSKMETNIPGIYAAGDICTYEGKV 295 Query: 297 AITSAGSG--CMAALDAEKYLT 316 + + G G A +A+ Y Sbjct: 296 KLIACGFGEAPTAVNNAKAYFD 317 >5XHU-A nrPDB Length = 329 Score = 229 bits (583), Expect = 1e-60, Method: Composition-based stats. Identities = 69/318 (21%), Positives = 127/318 (39%), Gaps = 15/318 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLT---TTTEIENFPGFPDG 61 VTIIG GP A Y E+K + E + GG+++ I + G P G Sbjct: 4 DVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPK----LGGKVSLFFPEKIIRDIGGIP-G 58 Query: 62 LTGSELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 + G +L+++++EQ+ F +I+ + V+ + + T + + T +ILA G Sbjct: 59 IAGKQLIEQLKEQAATFDPDIVLNQRVTGFERLDDGTIVLT--GSEGKKHYTRTVILACG 116 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ++ E + + F+ K + + GGGD+A + A L + V Sbjct: 117 MGTLEVNEFDSEDAARYAGKNLHYGVEKLDAFKGKRVVISGGGDTAVDWANELEPIAASV 176 Query: 181 FMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLP 240 ++ R++ + K + +L + GD + + ++ + +T+ + D+ Sbjct: 177 TVVHRREEFGGMESSVTKM-KQSSVRVLTPYRLEQLNGDEEGIKSVTVCHTESGQRKDIE 235 Query: 241 VSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGD--VQDSKYRQAI 298 + L G + E G +K T++PG F AGD +SK R Sbjct: 236 IDELIINHGFKIDLGPMMEWGLEIEEGRVKA-DRHMRTNLPGVFVAGDAAFYESKLRLIA 294 Query: 299 TSAGSGCMAALDAEKYLT 316 G A A+ YL Sbjct: 295 GGFTEGPTAVNSAKAYLD 312 >5YGQ-A nrPDB Length = 342 Score = 226 bits (577), Expect = 8e-60, Method: Composition-based stats. Identities = 74/323 (22%), Positives = 126/323 (39%), Gaps = 18/323 (5%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 + V I+G+GP A L ++K L + + G +L I + PG P Sbjct: 5 IKTDVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVG-GQCAELYPEKPIYDIPGIP-M 62 Query: 62 LTGSELMDRMREQSTKFGTE-IITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 +TG L + + EQ F ++E V V+ P + + +++A G Sbjct: 63 VTGHGLTEALMEQIKPFNPTFHLSEMVENVEKIGDPG--FRVTTNAGKVFECTVLVVAAG 120 Query: 121 AS---AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 KR +PG E Y + + FR K + ++GGGDSA + L Sbjct: 121 GGSFLPKRPPVPGVEAYEGTSVHY---AVRKMEDFRGKDILIVGGGDSALDWTLNLNPIA 177 Query: 178 SKVFMLVRKDHLRASTIMQKRAEK---NEKIEILYNTVALEAKGDGKLLNALRIKNTKKN 234 + ++ R+D R + ++ + + K+++ E +GD L +K N Sbjct: 178 KSMTLVHRRDDFRGAPHSVEQMRQLVASGKLDLKIG-QITELQGDNGQLTGATVK-LNDN 235 Query: 235 EETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQD--S 292 + + + G T VA E I G+ T+VPG FA GD+ Sbjct: 236 TTSQIKCDAMLPFFGLTMKLGPVANWGLDLENNLIPVDTGTFETNVPGIFAIGDINTYPG 295 Query: 293 KYRQAITSAGSGCMAALDAEKYL 315 K + ++ G + A A KY+ Sbjct: 296 KLKLILSGFHEGALMAQKAVKYV 318 >5JFC-L nrPDB Length = 474 Score = 216 bits (549), Expect = 1e-56, Method: Composition-based stats. Identities = 83/344 (24%), Positives = 136/344 (39%), Gaps = 54/344 (15%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV IIG+GPA T A LA+ + +YE + GG L G P+ Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQ----PGGVLIY--------GIPEFRLP 203 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS-A 123 E++ + E + G +I T + ++ + E E+ DAI + TGA Sbjct: 204 KEIVKKELENLRRLGVKIETNVLVGKTIT------FEELREE-----YDAIFIGTGAGTP 252 Query: 124 KRMHLPG----------EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFL 173 + PG E + A + PI K +AVIGGG++A + A+ Sbjct: 253 RIYPWPGVNLNGIYSANEFLTRINLMKAYKFPEYDTPIKVGKRVAVIGGGNTAMDAARSA 312 Query: 174 TKYGSKVFMLVRKDHL-RASTIMQKRAEKNEKIEILYNTVALEAKGD-GKLLNALRIKNT 231 + G++V++L R+ + + + + E ++ ++ GD L A+ ++ Sbjct: 313 LRLGAEVWILYRRTRKEMTAREEEIKHAEEEGVKFMFLVTPKRFIGDENGNLKAIELEKM 372 Query: 232 K--------------KNEETDLPVSGLFYAIGHTPATKIVA--GQVDTDEAGYIKTVPGS 275 K E + AIG TP + + DE G I V + Sbjct: 373 KLGEPDESGRRRPIPTGETFIMEFDTAIIAIGQTPNKTFLETVPGLKVDEWGRI-VVDEN 431 Query: 276 SLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTSLE 319 +TS+PG FA GD + I + G G AA +YL+ + Sbjct: 432 LMTSIPGVFAGGDAIRGEA-TVILAMGDGRKAAKAIHQYLSKEK 474 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 39/218 (17%), Positives = 67/218 (30%), Gaps = 15/218 (6%) Query: 57 GFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAII 116 G P + + +RE + ++ T E A + Sbjct: 55 GCPVHINIPGFIKALREN--RDNPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACV 112 Query: 117 LATGASAK---RMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGDSACEEAQF 172 + ++ + + GI + + I RN K +A+IG G + A Sbjct: 113 VGKVGDPINIGKLERFVADYAREHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAAD 172 Query: 173 LTKYGSKVFM---LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIK 229 L K G +V + L + + I + R K + L N L K + +L I Sbjct: 173 LAKMGYEVTIYEALHQPGGVLIYGIPEFRLPKEIVKKELENLRRLGVKIETNVLVGKTIT 232 Query: 230 NTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAG 267 + EE D IG T + + G Sbjct: 233 FEELREEYDA------IFIGTGAGTPRIYPWPGVNLNG 264 >4YRY-B nrPDB Length = 468 Score = 213 bits (542), Expect = 1e-55, Method: Composition-based stats. Identities = 86/346 (24%), Positives = 135/346 (39%), Gaps = 55/346 (15%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 KV ++GSGPA TAA LA+ ++E GG L G P+ Sbjct: 139 KKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHK----PGGVLVY--------GIPEF 186 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 +++R K G TV K K+ +E DA+ + TGA Sbjct: 187 RLPKRIVEREVSYIRKLGVNFHLNTVV-----GKTVKVKELLSE------YDAVFIGTGA 235 Query: 122 S-AKRMHLPG----------EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEA 170 K M +PG E + A + PI K +AVIG G++A + A Sbjct: 236 GTPKFMGIPGTNLNGVYSANEFLTRVNLMKAYLFPEYDTPIRVGKKVAVIGAGNTAMDAA 295 Query: 171 QFLTKYGS-KVFMLVRKDHL-RASTIMQKRAEKNEKIEILYNTVALEAKGDG----KLLN 224 + + G+ KV+++ R+ + + E IE L+ T+ + GD + + Sbjct: 296 RSALRLGAEKVYIVYRRTEREMPARREEYHHALEEGIEFLWLTLPIRYIGDANGNVEAME 355 Query: 225 ALRIKNTKK------------NEETDLPVSGLFYAIGHTPATKIVA--GQVDTDEAGYIK 270 +R++ + L V + AIG P +++ ++ +E GYIK Sbjct: 356 CVRMELKEADGSGRPRPVPIEGSNFVLEVDMVIEAIGQGPNRVLLSEFPGLELNERGYIK 415 Query: 271 TVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLT 316 + TSV G FA GD+ I + G+G AA YLT Sbjct: 416 ADEDTGATSVKGVFAGGDIVTGAA-TVIKAMGAGKKAAQFIHSYLT 460 >6GAR-A nrPDB Length = 349 Score = 210 bits (536), Expect = 4e-55, Method: Composition-based stats. Identities = 70/324 (21%), Positives = 139/324 (42%), Gaps = 23/324 (7%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE--IENFPGFPDGL 62 VT+IG GPA +A Y E++ + E GG++ E I + G + Sbjct: 8 DVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPH----LGGKIHVYPEKMIWDVGGLL-PV 62 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 TG +L++++ +Q F E++ +T + + ++ +T E + +I+ATG+ Sbjct: 63 TGDKLIEQLVQQGLTFKPEVVLDTKVESIIRNQD-GTFTLKTSTGEEHFSKTVIVATGSG 121 Query: 123 ---AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK 179 +++ + G E + +S ++ F+ K + + GGG+SA + A L K Sbjct: 122 ILKPQKLSIEGAERFE---VSNLNYTVKSLKRFKGKTVIISGGGNSAVDWANELEPIAKK 178 Query: 180 VFMLVRKDHLRASTIMQKRAEKNEKIEILYNT--VALEAKGDGKLLNALRIKNTKKNEET 237 V++ RK+ L K+ N E +NT L A + + + + + N + E + Sbjct: 179 VYVTYRKEELSGHEAQVKQLM-NSSAECFFNTSITKLIAGDNHEAIEYVELTNHETGEVS 237 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDE---AGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 LP+ + G+ ++ + D Y +S +SV G +AAGD+ + Sbjct: 238 HLPIDEVIINHGYERDITLLENS-ELDVAIIDNYYIAGNANSESSVDGLYAAGDILKHEG 296 Query: 295 R--QAITSAGSGCMAALDAEKYLT 316 + + A A++++ Sbjct: 297 KLHLIAGAFQDAGNAVNKAKQFIQ 320 >3AB1-A nrPDB Length = 360 Score = 210 bits (535), Expect = 7e-55, Method: Composition-based stats. Identities = 69/318 (21%), Positives = 121/318 (38%), Gaps = 13/318 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 +TIIG GP AA I + E M G L I + GFP+ + Sbjct: 16 DLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQL-AALYPEKHIYDVAGFPE-VPA 73 Query: 65 SELMDRMREQSTKFGTEII-TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +L++ + Q+ ++ +++ ETV+K + + A+++A G A Sbjct: 74 IDLVESLWAQAERYNPDVVLNETVTKYTKLDD--GTFETRTNTGNVYRSRAVLIAAGLGA 131 Query: 124 KRMH-LPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 LP S+ +V F+ K + ++GGGDSA + L K + V + Sbjct: 132 FEPRKLPQLGNIDHLTGSSVYYAVKSVEDFKGKRVVIVGGGDSALDWTVGLIKNAASVTL 191 Query: 183 LVRKDHLRAS---TIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDL 239 + R + +RA N I++ T + +L + ++++ ++ T + Sbjct: 192 VHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESNGVLTRVHLRSSDGSKWT-V 250 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 L IG +A D + V TSV G +AAGD+ + I Sbjct: 251 EADRLLILIGFKSNLGPLARW-DLELYENALVVDSHMKTSVDGLYAAGDIAYYPGKLKII 309 Query: 300 SAG--SGCMAALDAEKYL 315 G MA + Y+ Sbjct: 310 QTGLSEATMAVRHSLSYI 327 >5VJ7-A nrPDB Length = 476 Score = 200 bits (510), Expect = 5e-52, Method: Composition-based stats. Identities = 82/343 (23%), Positives = 140/343 (40%), Gaps = 55/343 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV IIG+GPA T A LA+ + +YE + GG LT G P+ Sbjct: 156 KVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQ----PGGVLTY--------GIPEFRLP 203 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS-A 123 E++ + ++ + G EI T+ + ++ + DA+ + TGA Sbjct: 204 KEILRKELKKLSLLGVEIKTDHIVGKTITIQEL-----------LQEYDAVFIGTGAGTP 252 Query: 124 KRMHLPG----------EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFL 173 K ++PG E + A + PI K + VIG G++A + A+ Sbjct: 253 KLPNIPGINLNGIYSANEFLTRINLMKAYKFPEYDTPIVVGKKVVVIGAGNTAMDAARSA 312 Query: 174 TKYGSKVFMLVRK-DHLRASTIMQKRAEKNEKIEILYNTVALEAKGD-GKLLNALRIKNT 231 + G++V + R+ + I + + + E ++ ++ +E GD + A++ + Sbjct: 313 LRLGAEVTIAYRRGREDMTARIEEVKHAEEEGVKFMFFVNPVEFIGDENGNVKAVKFEKM 372 Query: 232 KKNEETD---------------LPVSGLFYAIGHTPATKI--VAGQVDTDEAGYIKTVPG 274 K EE D + + AIG TP + ++ DE G I V Sbjct: 373 KPLEERDSRGKRKIVGTGEYITVEADTVIIAIGQTPNKVLWRATPELKVDEWGRI-VVDE 431 Query: 275 SSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTS 317 + +TS+PG FA GD + I + G G AA +YL+ Sbjct: 432 NLMTSIPGVFAGGDAIRGEA-TVILAMGDGRKAAKAIHQYLSK 473 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 30/223 (13%), Positives = 62/223 (27%), Gaps = 29/223 (13%) Query: 57 GFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAII 116 G P + + +RE + ++ T E A + Sbjct: 55 GCPVHINIPGFIKALREN--RDNPSKAVREALRIIWRDNTLPAITGRVCPQEEQCEGACV 112 Query: 117 LATGASAK---RMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGDSACEEAQF 172 + ++ + + GI + + I RN K +A+IG G + A Sbjct: 113 VGKVGDPINIGKLERFVADYAREHGIDDELLLEEIKGIKRNGKKVAIIGAGPAGLTCAAD 172 Query: 173 LTKYGSKVFMLVRKD-----------HLRASTIMQKRAEKNEKIEILYNTVALEAKGDGK 221 L K G +V + R + ++ K + + +E K D Sbjct: 173 LAKMGYEVTIYEALHQPGGVLTYGIPEFRLPKEILRKELKKLSL------LGVEIKTDHI 226 Query: 222 LLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTD 264 + + I+ +F G ++ + Sbjct: 227 VGKTITIQEL------LQEYDAVFIGTGAGTPKLPNIPGINLN 263 >4FK1-A nrPDB Length = 304 Score = 186 bits (473), Expect = 9e-48, Method: Composition-based stats. Identities = 61/314 (19%), Positives = 118/314 (37%), Gaps = 25/314 (7%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGF-- 58 M + +IG+GPA A++ L RA + L++ +N GF Sbjct: 4 MKYIDCAVIGAGPAGLNASLVLGRARKQIALFDN----------NTNRNRVTQNSHGFIT 53 Query: 59 PDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 DG+ E + + K+ + E + V ++ + L+ +D + ++LA Sbjct: 54 RDGIKPEEFKEIGLNEVMKYPSVHYYEK-TVVMITKQSTGLFEIVTKDHTKYLAERVLLA 112 Query: 119 TGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIG-GGDSACEEAQFLTKYG 177 TG + +P Y+ K + +C CDG +++PL +I D + + + Sbjct: 113 TGMQEEFPSIPNVREYYGKSLFSCPYCDGWE--LKDQPLIIISENEDHTLHMTKLVYNWS 170 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEET 237 + + + + L + TIM + + KN I ++ ++ +G+G L + + + E Sbjct: 171 TDLVIATNGNEL-SQTIMDELSNKN--IPVITESIRT-LQGEGGYLKKVEFHSGLRIER- 225 Query: 238 DLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQA 297 G P I + G + TS + AG+ Sbjct: 226 ---AGGFIVPTFFRPNQFIEQLGCELQSNGTF-VIDDFGRTSEKNIYLAGETTTQGPSSL 281 Query: 298 ITSAGSGCMAALDA 311 I +A G AA+ Sbjct: 282 IIAASQGNKAAIAI 295 >5TWC-A nrPDB Length = 344 Score = 163 bits (413), Expect = 8e-41, Method: Composition-based stats. Identities = 66/324 (20%), Positives = 134/324 (41%), Gaps = 23/324 (7%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQL--TTTTEIENFPGFPDGL 62 VTIIG GP+ A+ Y ++ L + GG++ I + G Sbjct: 3 DVTIIGGGPSGLYASFYAGLRDMSVRLID----VQSELGGKMRIYPEKIIWDIGGIAPKP 58 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA- 121 E++ +Q F E+ VD+ K + + E E T+ A+I+A GA Sbjct: 59 C-HEILKDTIKQGLYFKPEVHLNE-RVVDIRKKAERHFEVETEAGEIYTSKAVIIAIGAG 116 Query: 122 --SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK 179 + K++ + G E Y + + F++K + + GGG++A + A + K Sbjct: 117 IINPKQLDVKGVERYQLTNLHY---VVQSYRRFKDKDVLISGGGNTALDWAHDIAKIAKS 173 Query: 180 VFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKG--DGKLLNALRIKNTKKNEET 237 V ++ RK+ + M+ +++ T G D ++ + +++ + + Sbjct: 174 VTVVYRKEDVSGHEAMKTLVTDL-NVKLCPKTRIKYLVGNDDETHISEVVLEHVESGDRH 232 Query: 238 DLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQ--DS 292 + + + G ++ + ++D + +K G++ TS+PG +A GD+ D+ Sbjct: 233 TVKFDDVIISHGFDRCNTLLSETSSKLDMHDDCRVKGF-GNTTTSIPGIYACGDIVYHDA 291 Query: 293 KYRQAITSAGSGCMAALDAEKYLT 316 K ++ G AA A+ Y+ Sbjct: 292 KSHLIASAFSDGANAANLAKTYIQ 315 >2BC1-A nrPDB Length = 490 Score = 154 bits (390), Expect = 4e-38, Method: Composition-based stats. Identities = 72/344 (20%), Positives = 130/344 (37%), Gaps = 62/344 (18%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEI----KPILYEGMMANGIAAGGQLTTTTEIENFPGFP 59 +K+ ++G+ A TA I + ++++ + I+ G E G P Sbjct: 36 SKIVVVGANHAG-TACIKTMLTNYGDANEIVVFD--QNSNISFLGSGMALWIGEQIAG-P 91 Query: 60 DGLTGSELMDRMREQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 +GL S+ +E+ G ++ E+ V +D +K + E D +I A Sbjct: 92 EGLFYSD-----KEELESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVETY--DKLIFA 144 Query: 119 TGASAKRMHLPGEETYWQKGISACAVCD--GAVPIFRN-------------KPLAVIGGG 163 TG+ + G E + A + V +++N K +AV+G G Sbjct: 145 TGSQPILPPIKGAEIKEG-SLEFEATLENLQFVKLYQNSADVIAKLENKDIKRVAVVGAG 203 Query: 164 DSACEEAQFLTKYGSKVFMLVRKDHLRAS------TIMQKRAEKNEKIEILYNTVALEAK 217 E A+ + G +V ++ D A T + + + I++ + E Sbjct: 204 YIGVELAEAFQRKGKEVVLIDVVDTCLAGYYDRDLTDLMAKNMEEHGIQLAFGETVKEVA 263 Query: 218 GDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSL 277 G+GK+ + KN + V + A+G P T + G++D G V Sbjct: 264 GNGKVEKIITDKN-------EYDVDMVILAVGFRPNTTLGNGKIDLFRNGAFL-VNKRQE 315 Query: 278 TSVPGFFAAGDV--------QDSKY--------RQAITSAGSGC 305 TS+PG +A GD +D+ Y R I +A + C Sbjct: 316 TSIPGVYAIGDCATIYDNATRDTNYIALASNAVRTGIVAAHNAC 359 >3CGD-A nrPDB Length = 480 Score = 154 bits (389), Expect = 5e-38, Method: Composition-based stats. Identities = 72/308 (23%), Positives = 120/308 (38%), Gaps = 47/308 (15%) Query: 7 TIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFP--GFPDGLTG 64 IIG A +AA+ + R + E + G EI ++ G P ++G Sbjct: 40 VIIGGDAAGMSAAMQIVRND------ENANVVTLEKG-------EIYSYAQCGLPYVISG 86 Query: 65 ------SELMDRMREQSTKFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIIL 117 + ++ K+G + + V+KVD K +D + D +++ Sbjct: 87 AIASTEKLIARNVKTFRDKYGIDAKVRHEVTKVDTEKKIVYAEHTKTKDVFEFSYDRLLI 146 Query: 118 ATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR------NKPLAVIGGGDSACEEAQ 171 ATG R +P E +G+ A I + + + +IGGG E A+ Sbjct: 147 ATGV---RPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKVEDVTIIGGGAIGLEMAE 203 Query: 172 FLTKYGSKVFMLVRKDHL------RASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNA 225 + G KV M+ R DH+ + + K A+K+ IEIL N KG+ ++ Sbjct: 204 TFVELGKKVRMIERNDHIGTIYDGDMAEYIYKEADKHH-IEILTNENVKAFKGNERVEAV 262 Query: 226 LRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG-QVDTDEAGYIKTVPGSSLTSVPGFF 284 K T K + ++G P T + G + T+ G I+ V T+V + Sbjct: 263 ETDKGTYK-------ADLVLVSVGVKPNTDFLEGTNIRTNHKGAIE-VNAYMQTNVQDVY 314 Query: 285 AAGDVQDS 292 AAGD Sbjct: 315 AAGDCATH 322 Score = 35.0 bits (79), Expect = 0.049, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 37/126 (29%), Gaps = 24/126 (19%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 VTIIG G A K + E G G Sbjct: 188 DVTIIGGGAIGLEMAETFVELGKKVRMIERNDHIGTIYDG-------------------- 227 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 ++ + + +++ K EI+T K ++ + D D ++++ G Sbjct: 228 -DMAEYIYKEADKHHIEILTNENVKAFKGNERVEAVET---DKGTYKADLVLVSVGVKPN 283 Query: 125 RMHLPG 130 L G Sbjct: 284 TDFLEG 289 >5U1O-A nrPDB Length = 458 Score = 153 bits (388), Expect = 7e-38, Method: Composition-based stats. Identities = 69/315 (21%), Positives = 117/315 (37%), Gaps = 48/315 (15%) Query: 22 LARAEIKPILYEG------------MMANGIAAGGQLT--TTTEIENFPGFPDGLTG--- 64 A K L E + + G Q+ E++ GF + G Sbjct: 30 AAMYGAKVALIEAQDLGGTCVNVGCVPKKVMWHGAQIAEAMNLYAEDY-GFDVDVKGFDW 88 Query: 65 SELMDRMREQSTK----FGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 S+L++ + + + + V+ V F + E T D I++A G Sbjct: 89 SKLVESRQAYIGRIHQSYDRVLGNNKVN-VIKGFAKFVDEKTVEVNGEHYTADHILIAVG 147 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 ++PG E GI + D A + K +AV+G G A E A L G++ Sbjct: 148 GRPTIPNIPGAE----YGIDSNGFFDLAE---QPKRVAVVGAGYIAVEIAGVLHALGTET 200 Query: 181 FMLVRK-------DHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKK 233 + VRK D + T+++ + + ++V E + L ++N + Sbjct: 201 HLFVRKESPLRSFDPMIIDTLVEVMEAEGPTLH--THSVPKEVVKEADGSLTLHLENGES 258 Query: 234 NEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQ 290 V L +AIG PAT + + V T+E GYIK V T+V G + GD+ Sbjct: 259 Q-----NVDQLIWAIGRHPATDAINLASTGVATNEKGYIK-VDEYQETNVKGIYCVGDIM 312 Query: 291 DSKYRQAITSAGSGC 305 + + +G Sbjct: 313 EGGIELTPVAVKAGR 327 >3Q6J-A nrPDB Length = 523 Score = 152 bits (384), Expect = 2e-37, Method: Composition-based stats. Identities = 64/341 (18%), Positives = 108/341 (31%), Gaps = 50/341 (14%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIA----------------------- 41 IG G A + YL + ++ + G + Sbjct: 45 DAIFIGGGAAGRFGSAYLRAMGGRQLIVDRWPFLGGSCPHNACVPHHLFSDCAAELMLAR 104 Query: 42 -AGGQLTTTTEIENFPGFPDGLT-------GSELMDRMREQSTKFGTEIITETVSKVDLS 93 GQ E G + + G + + + + E I +KV + Sbjct: 105 TFSGQYWFPDMTEKVVGIKEVVDLFRAGRNGPHGIMNFQSK-EQLNLEYILNCPAKVIDN 163 Query: 94 SKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR 153 + +ILA GA + +PG KG+ A + Sbjct: 164 -------HTVEAAGKVFKAKNLILAVGAGPGTLDVPGVNA---KGVFDHATLVEELDYEP 213 Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAE-----KNEKIEIL 208 + V+GG +A E F G + MLVR + L+ + RA K + +EI+ Sbjct: 214 GSTVVVVGGSKTAVEYGCFFNATGRRTVMLVRTEPLKLIKDNETRAYVLDRMKEQGMEII 273 Query: 209 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGY 268 + + D + T E + +F +G P + +A + D Sbjct: 274 SGSNVTRIEEDANGRVQAVVAMTPNGEMR-IETDFVFLGLGEQPRSAELAKILGLDLGPK 332 Query: 269 IKT-VPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 + V TSVP +A GD+ + + SGC AA Sbjct: 333 GEVLVNEYLQTSVPNVYAVGDLIGGPM-EMFKARKSGCYAA 372 >3OC4-A nrPDB Length = 452 Score = 150 bits (378), Expect = 1e-36, Method: Composition-based stats. Identities = 69/298 (23%), Positives = 110/298 (36%), Gaps = 30/298 (10%) Query: 5 KVTIIGSGPAAHTAAIYLARA--EIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 K+ IIG+ A +AAI + + + L + G +GG N + Sbjct: 4 KIVIIGASFAGISAAIASRKKYPQAEISLIDKQATVGYLSGGLSAYFNHTINELHEARYI 63 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 T EL R Q + ++ V +D+ ++ E+ + + D +ILATGAS Sbjct: 64 TEEEL----RRQKIQL---LLNREVVAMDVENQLIAWT--RKEEQQWYSYDKLILATGAS 114 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGDSACEEAQFLTKYGSKVF 181 + G +T + AVP+ N + +AVIG G E FL K V Sbjct: 115 QFSTQIRGSQTEKLLKYKFLSGALAAVPLLENSQTVAVIGAGPIGMEAIDFLVKMKKTVH 174 Query: 182 MLVRKDHLRASTI-------MQKRAEKNEKIEILYNTVA-LEAKGDGKLLNALRIKNTKK 233 + ++L +QK EK I TV +E +G +L Sbjct: 175 VFESLENLLPKYFDKEMVAEVQKSLEKQAVIFHFEETVLGIEETANGIVLET-------- 226 Query: 234 NEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQD 291 E ++ +A+ P + ++ + I V TSVP FA GD Sbjct: 227 -SEQEISCDSGIFALNLHPQLAYLDKKIQRNLDQTI-AVDAYLQTSVPNVFAIGDCIS 282 >1YQZ-A nrPDB Length = 438 Score = 149 bits (376), Expect = 2e-36, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 84/220 (38%), Gaps = 17/220 (7%) Query: 84 TETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACA 143 V ++ + + + + D +IL+ GASA + + T+ + + Sbjct: 78 YHEVIAINDERQTVSVLNRKTNEQFEESYDKLILSPGASANSLGFESDITFTLRNLEDTD 137 Query: 144 VCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD---HLRASTIMQKRAE 200 D + + + V+G G + E + L + G ++ R D L + + Q + Sbjct: 138 AIDQFIKANQVDKVLVVGAGYVSLEVLENLYERGLHPTLIHRSDKINKLMDADMNQPILD 197 Query: 201 KNEKIEILY--NTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVA 258 + +K EI Y N G+ + ++++ + +G P +K + Sbjct: 198 ELDKREIPYRLNEEINAINGNEITFKSGKVEH----------YDMIIEGVGTHPNSKFIE 247 Query: 259 -GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQA 297 + D G+I V T+VP +A GD+ S YR Sbjct: 248 SSNIKLDRKGFIP-VNDKFETNVPNIYAIGDIATSHYRHV 286 >5VDN-A nrPDB Length = 463 Score = 144 bits (363), Expect = 5e-35, Method: Composition-based stats. Identities = 55/202 (27%), Positives = 85/202 (42%), Gaps = 25/202 (12%) Query: 97 FKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKP 156 F + E +T D I++ATG +PG E GI + + K Sbjct: 130 FVDAHTVEVNGETITADHILIATGGRPSHPDIPGAE----YGIDSDGFFELDE---MPKR 182 Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRK-------DHLRASTIMQKRAEKNEKIEILY 209 +AV+G G A E A L G++ + VRK D L T+++ + K+ Sbjct: 183 VAVVGAGYIAVEIAGVLNGLGTETHLFVRKHAPLRTFDPLIVETLLEVMNTEGPKLHTES 242 Query: 210 NTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP---ATKIVAGQVDTDEA 266 A+ DG L L+++N T++ V L +AIG P + V T++ Sbjct: 243 VPKAVIKNADGSL--TLQLENG-----TEVTVDHLIWAIGREPATDNLNLSVTGVKTNDK 295 Query: 267 GYIKTVPGSSLTSVPGFFAAGD 288 GYI+ V T+V G +A GD Sbjct: 296 GYIE-VDKFQNTNVKGIYAVGD 316 >2R9Z-A nrPDB Length = 463 Score = 138 bits (349), Expect = 2e-33, Method: Composition-based stats. Identities = 69/338 (20%), Positives = 123/338 (36%), Gaps = 62/338 (18%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGM------MANGIAAGGQLTTTTE----I 52 H + IG G A A + L E + G + + + Sbjct: 4 HFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKALGGTCVNVGCVPKKVMWYASHLAEAV 63 Query: 53 ENFPGF-----------PDGLTGSE-----LMDRMREQSTKFGTEIITETVSKVDLSSKP 96 + PGF P + G + + + G +++VD ++ Sbjct: 64 RDAPGFGVQASGGTLDWPRLVAGRDRYIGAINSFWDGYVERLG-------ITRVDGHAR- 115 Query: 97 FKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRN-K 155 F + + ++ D I++ATG LPG E GI++ DG + + K Sbjct: 116 FVDAHTIEVEGQRLSADHIVIATGGRPIVPRLPGAEL----GITS----DGFFALQQQPK 167 Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVF-------MLVRKDHLRASTIMQKRAEKNEKIEIL 208 +A+IG G E A L +GS+V +L + D L ++T+ + + + + Sbjct: 168 RVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRLLFQFDPLLSATLAENMHAQGIETHLE 227 Query: 209 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDE 265 + ALE G L A ++ + E + +A+G P T + A ++ Sbjct: 228 FAVAALERDAQGTTLVA---QDGTRLEG----FDSVIWAVGRAPNTRDLGLEAAGIEVQS 280 Query: 266 AGYIKTVPGSSLTSVPGFFAAGDVQDSK-YRQAITSAG 302 G + T T+VPG +A GD+ +AG Sbjct: 281 NGMVPT-DAYQNTNVPGVYALGDITGRDQLTPVAIAAG 317 >6N7F-A nrPDB Length = 453 Score = 138 bits (348), Expect = 3e-33, Method: Composition-based stats. Identities = 70/329 (21%), Positives = 111/329 (33%), Gaps = 47/329 (14%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEG------------MMANGIAAGGQLTTT--T 50 +IG G A +A A K +L EG + + G Q+ T Sbjct: 9 DYIVIGGGSAGIASANRAAMHGAKVLLAEGKEIGGTCVNLGCVPKKVMWYGAQVADILGT 68 Query: 51 EIENFPGF---PDGLTGSELMDRMREQSTKFGTEIITE-TVSKVDLSSK--PFKLWTEFN 104 +++ GF +L + + + VD FK Sbjct: 69 YAKDY-GFDFKEKAFDFKQLKANRQAYIDRIHASYERGFEQNGVDRIYDYAVFKDAHTVE 127 Query: 105 EDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGD 164 + T I++ATG + G + GIS+ K AV+G G Sbjct: 128 IAGQLYTAPHILIATGGHPVFPDIEGAQ----YGISSDGFFALDE---VPKRTAVVGAGY 180 Query: 165 SACEEAQFLTKYGSKVFMLVRKD-HLRA------STIMQKRAEKNEKIEILYNTVALEAK 217 A E A L GSK + +R D LR+ ++ + A ++ + Sbjct: 181 IAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDEMAVNGPRLHTHAEVAKVVKN 240 Query: 218 GDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTVPG 274 D L L+ + ++ V L +AIG P + + V ++ GYI+T Sbjct: 241 TDESLTLYLK-------DGQEVEVDQLIWAIGRKPNLEGFSLDKTGVTLNDKGYIET-DA 292 Query: 275 SSLTSVPGFFAAGDVQDS-KYRQAITSAG 302 TSV G +A GDV +AG Sbjct: 293 YENTSVKGIYAVGDVNGKLALTPVAVAAG 321 >1ZDL-A nrPDB Length = 517 Score = 134 bits (338), Expect = 4e-32, Method: Composition-based stats. Identities = 64/348 (18%), Positives = 113/348 (32%), Gaps = 51/348 (14%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 + +IG G A A+ K + + + + L T N P L Sbjct: 34 DLLVIGGGSGGLACAKEAAQLGKKVAVADYVEPSPRGTKWGLGGTCV--NVGCIPKKLMH 91 Query: 65 SE-LMDRMREQSTKFGTEII-----------------------TETVSKVDLSSKPFKLW 100 L+ M + +G E+ V D K F + Sbjct: 92 QAALLGGMIRDAHHYGWEVAQPVQHNWKTMAEAVQNHVKSLNWGHRVQLQDRKVKYFNIK 151 Query: 101 TEFNEDAEP-----------VTTDAIILATGASAKRM-HLPGEETYWQKGISACAVCDGA 148 F ++ ++ + I++ATG + + G Y GI++ + Sbjct: 152 ASFVDEHTVRGVDKGGKATLLSAEHIVIATGGRPRYPTQVKGALEY---GITSDDIF--W 206 Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA----STIMQKRAEKNEK 204 + K L V+G A E A FLT G +++R LR + + ++ Sbjct: 207 LKESPGKTL-VVGASYVALECAGFLTGIGLDTTVMMRSIPLRGFDQQMSSLVTEHMESHG 265 Query: 205 IEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQV 261 + L V K + ++ +E + +AIG P T + + Sbjct: 266 TQFLKGCVPSHIKKLPTNQLQVTWEDHASGKEDTGTFDTVLWAIGRVPETRTLNLEKAGI 325 Query: 262 DTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAAL 309 T+ V TSVP +A GDV + + T+ +G + A Sbjct: 326 STNPKNQKIIVDAQEATSVPHIYAIGDVAEGRPELTPTAIKAGKLLAQ 373 >2X8H-A nrPDB Length = 598 Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats. Identities = 55/223 (24%), Positives = 88/223 (39%), Gaps = 21/223 (9%) Query: 100 WTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAV 159 T+ N+ +T + IILATG K +PG Y GI++ + ++P F K L V Sbjct: 238 ITDKNQKVSTITGNKIILATGERPKYPEIPGAVEY---GITSDDLF--SLPYFPGKTL-V 291 Query: 160 IGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-STIMQKRA---EKNEKIEILYNTVALE 215 IG A E A FL G V ++VR LR M ++ +N ++ V E Sbjct: 292 IGASYVALECAGFLASLGGDVTVMVRSILLRGFDQQMAEKVGDYMENHGVKFAKLCVPDE 351 Query: 216 AK-------GDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG---QVDTDE 265 K + K L + ++ + + +A+G P V V D+ Sbjct: 352 IKQLKVVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKVLCETVGVKLDK 411 Query: 266 AGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 G + T+V +A GD+ K + + +G A Sbjct: 412 NGRV-VCTDDEQTTVSNVYAIGDINAGKPQLTPVAIQAGRYLA 453 >4LA1-A nrPDB Length = 602 Score = 132 bits (331), Expect = 2e-31, Method: Composition-based stats. Identities = 52/223 (23%), Positives = 87/223 (39%), Gaps = 21/223 (9%) Query: 100 WTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAV 159 TE N+ +T + IILATG K +PG Y GI++ + ++P F K L V Sbjct: 244 ITEKNKKVSTITGNKIILATGERPKYPEIPGAIEY---GITSDDLF--SLPYFPGKTL-V 297 Query: 160 IGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-STIMQKRA---EKNEKIEILYNTVALE 215 +G A + A FL G V ++VR LR M ++ +N ++ V E Sbjct: 298 VGASYVALKCAGFLASLGGDVTVMVRSILLRGFDQQMAEKVGDYMENHGVKFAKLCVPDE 357 Query: 216 A-------KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG---QVDTDE 265 + K L + ++ + + +A+G P + V D+ Sbjct: 358 ITQLKPVDTENNKPGLLLVKGHYTDGKKFEEEFETVIFAVGREPQLSKLNCEAVGVKLDK 417 Query: 266 AGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 G + T+V +A GD+ K + + +G A Sbjct: 418 NGRV-VCSDDEQTTVSNIYAIGDINAGKPQLTPVAIHAGRYLA 459 >6DU7-A nrPDB Length = 448 Score = 131 bits (330), Expect = 4e-31, Method: Composition-based stats. Identities = 54/208 (25%), Positives = 87/208 (41%), Gaps = 26/208 (12%) Query: 96 PFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNK 155 F + + E + I++ATGA ++PG E G S +P + Sbjct: 115 EFVDSHTVSVNGELIRAKHIVIATGAHPSIPNIPGAEL---GGSSDDVFAWEELP----E 167 Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD-HLRA--STIMQKRAEKNEKIEILYNT- 211 +A++G G A E A L +G K + VR+D LR S I++ ++ E+ + +T Sbjct: 168 SVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRPLRGFDSYIVEGLVKEMERTNLPLHTH 227 Query: 212 ---VALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA---TKIVAGQVDTDE 265 V LE DG ++ + T S + +A G P ++ V +E Sbjct: 228 KVPVKLEKTTDGITIHF--------EDGTSHTASQVIWATGRRPNVKGLQLEKAGVTLNE 279 Query: 266 AGYIKTVPGSSLTSVPGFFAAGDVQDSK 293 G+I+ V T V G +A GDV K Sbjct: 280 RGFIQ-VDEYQNTVVEGIYALGDVTGEK 306 >1GEU-A nrPDB Length = 450 Score = 131 bits (329), Expect = 5e-31, Method: Composition-based stats. Identities = 47/226 (20%), Positives = 82/226 (36%), Gaps = 26/226 (11%) Query: 90 VDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAV 149 V F + E +T D I++ATG +PG E GI + A+ Sbjct: 110 VIKGFARFVDAKTLEVNGETITADHILIATGGRPSHPDIPGVE----YGIDSDGFF--AL 163 Query: 150 PIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV-------RKDHLRASTIMQKRAEKN 202 P + +AV+G G E + G+K + D + + T+++ + Sbjct: 164 PALP-ERVAVVGAGYIGVELGGVINGLGAKTHLFEMFDAPLPSFDPMISETLVEVMNAEG 222 Query: 203 EKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP---ATKIVAG 259 ++ N + + L +++ + V L +AIG P + A Sbjct: 223 P--QLHTNAIPKAVVKNTDGSLTLELEDGRSE-----TVDCLIWAIGREPANDNINLEAA 275 Query: 260 QVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGC 305 V T+E GYI V T++ G +A GD + +G Sbjct: 276 GVKTNEKGYI-VVDKYQNTNIEGIYAVGD-NTGAVELTPVAVAAGR 319 >5V36-A nrPDB Length = 453 Score = 131 bits (329), Expect = 5e-31, Method: Composition-based stats. Identities = 57/219 (26%), Positives = 86/219 (39%), Gaps = 24/219 (10%) Query: 96 PFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCD-GAVPIFRN 154 F E T I++ATG A +PG E GI++ + A+P Sbjct: 119 TFVDAHTVEVAGEHYTAPHILIATGGHALLPDIPGSE----YGITSDGFFELDAIP---- 170 Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD-HLR--ASTIMQKRAE--KNEKIEILY 209 K AV+G G A E + L GS+ + VR+D LR I+ + K + + Sbjct: 171 KRTAVVGAGYIAVEISGILHALGSETHLFVRRDRPLRKFDKEIVGTLVDEMKKDGPHLHT 230 Query: 210 NTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEA 266 +V E + L ++N + + V L +AIG TK + V D Sbjct: 231 FSVPKEVIKNTDNSLTLILENGE-----EYTVDTLIWAIGRAANTKGFNLEVTGVTLDSR 285 Query: 267 GYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGC 305 G+I T T+V G +A GDV K + +G Sbjct: 286 GFIAT-DAFENTNVEGLYALGDVN-GKLELTPVAVKAGR 322 >2AAQ-A nrPDB Length = 479 Score = 130 bits (327), Expect = 9e-31, Method: Composition-based stats. Identities = 55/225 (24%), Positives = 88/225 (39%), Gaps = 29/225 (12%) Query: 107 AEPVTTDAIILATGASAKRMH---LPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGG 163 + T I++ATG H +PG GI++ + + + ++G G Sbjct: 145 GKKYTAPHILIATGGMPSTPHESQIPGASL----GITSDGFFQ--LEELPGRSV-IVGAG 197 Query: 164 DSACEEAQFLTKYGSKVFMLVRKDH-LRASTIMQ----KRAEKNEKIEILYNTVALEAKG 218 A E A L+ GSK +++R D LR+ M +N +E+L + E K Sbjct: 198 YIAVEMAGILSALGSKTSLMIRHDKVLRSFDSMISTNCTEELENAGVEVLKFSQVKEVK- 256 Query: 219 DGKLLNALRIKNTKKNEET------DLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYI 269 K L+ L + V L +AIG P TK + + TD+ G+I Sbjct: 257 --KTLSGLEVSMVTAVPGRLPVMTMIPDVDCLLWAIGRVPNTKDLSLNKLGIQTDDKGHI 314 Query: 270 KTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKY 314 V T+V G +A GDV + + +G A +Y Sbjct: 315 -IVDEFQNTNVKGIYAVGDVCGKALLTPV-AIAAGRKLAHRLFEY 357 >4EMJ-A nrPDB Length = 410 Score = 126 bits (317), Expect = 1e-29, Method: Composition-based stats. Identities = 59/304 (19%), Positives = 109/304 (35%), Gaps = 36/304 (11%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 V IIG+G T A L + + + + P + Sbjct: 3 THVAIIGNGVGGFTTAQALRAEGFEGRISLIGDEPHLP-----------YDRPSLSKAVL 51 Query: 64 GSELMDR-MREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 L + ++ +G E + ++ ++++ + T +D ++ DAI++ATG+ Sbjct: 52 DGSLERPPILAEADWYG-EARIDMLTGPEVTALDVQTRTISLDDGTTLSADAIVIATGSR 110 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNK-----PLAVIGGGDSACEEAQFLTKYG 177 A+ M LPG + G+ G V + R+ L ++GGG CE A K G Sbjct: 111 ARTMALPGSQL---PGVVTLRTY-GDVQVLRDSWTSATRLLIVGGGLIGCEVATTARKLG 166 Query: 178 SKVFMLVRKDHLRASTIMQKR------AEKNEKIEILYNTVALEAKGDGKLLNALRIKNT 231 V +L D L + ++ +++ T + G+G+ ++ Sbjct: 167 LSVTILEAGDELLVRVLGRRIGAWLRGLLTELGVQVELGTGVVGFSGEGQ------LEQV 220 Query: 232 KKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQD 291 ++ +G PA ++ + G I G+ T G FA GDV Sbjct: 221 MASDGRSFVADSALICVGAEPADQLARQAGLACDRGVIVDHCGA--TLAKGVFAVGDVAS 278 Query: 292 SKYR 295 R Sbjct: 279 WPLR 282 >5TR3-A nrPDB Length = 481 Score = 125 bits (313), Expect = 4e-29, Method: Composition-based stats. Identities = 71/326 (21%), Positives = 108/326 (33%), Gaps = 46/326 (14%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMM--ANGIAAGGQLTTTTEIENFPGFPDGL 62 V +IG+GP + AAI A+ +K E +A GG I + Sbjct: 9 DVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKALLDSSW 68 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEF------------------- 103 E + G E+ + + V + K T Sbjct: 69 KYKEAKESFNVHGISTG-EVKMDVAAMVGRKAGIVKNLTGGVATLFKANGVTSIQGHGKL 127 Query: 104 -----------NEDAEPVTTDAIILATGASAK-RMHLPGEETYWQKGISACAVCDGAVPI 151 + E + + +ILA+G+ P ++ A AVP Sbjct: 128 LAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEF--QAVP- 184 Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT 211 K L VIG G E + G++V +L D + E + + Sbjct: 185 ---KRLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVSKEAQKTLTKQGLD 241 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETD--LPVSGLFYAIGHTPATKIV---AGQVDTDEA 266 + L A+ G +N ++ T N E + + L A+G P T + V DE Sbjct: 242 IKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRPVTTDLLASDSGVTIDER 301 Query: 267 GYIKTVPGSSLTSVPGFFAAGDVQDS 292 GYI V TSVPG +A GDV Sbjct: 302 GYI-FVDDYCATSVPGVYAIGDVVRG 326 Score = 35.0 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 46/308 (14%), Positives = 88/308 (28%), Gaps = 54/308 (17%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 ++ +IG+G AR + + E + +AA ++ Sbjct: 186 RLGVIGAGVIGLELGSVWARLGAEVTVLEALDTFLMAADTAVS----------------- 228 Query: 65 SELMDRMREQSTKFGTEIITE-TVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 ++ TK G +I V+ ++ ++ E + +T D +I+A G Sbjct: 229 ----KEAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVAVGRRP 284 Query: 124 KRMHL----PGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK 179 L G + I C +VP + G Sbjct: 285 VTTDLLASDSGVTIDERGYIFVDDYCATSVP---------------------GVYAIGDV 323 Query: 180 VFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDL 239 V ++ IM K K ++ Y+ + ++ + E L Sbjct: 324 VRGMMLAHKASEEGIMVVERIKGHKAQMNYDLIPSVIYTHPEIAWVGK-------TEQAL 376 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 G+ +G P D G++K + + V G G +Q Sbjct: 377 KAEGVEVNVGTFPFAASGRAMAANDTGGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAI 436 Query: 300 SAGSGCMA 307 + G A Sbjct: 437 AMEFGTSA 444 >4KPR-E nrPDB Length = 499 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 46/242 (19%), Positives = 90/242 (37%), Gaps = 17/242 (7%) Query: 81 EIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGIS 140 +++ E + ++ + + + ++ATG + + +PG++ Y IS Sbjct: 124 KVVYENAYGKFIGPHKIMATNNKGKE-KVYSAERFLIATGERPRYLGIPGDKEYC---IS 179 Query: 141 ACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-STIMQKR- 198 + + ++P K L V+G A E A FL G V ++VR LR M + Sbjct: 180 SDDLF--SLPYCPGKTL-VVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKI 236 Query: 199 --AEKNEKIEIL---YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA 253 + I+ + T + + + K+T E + + + A+G Sbjct: 237 GEHMEEHGIKFIRQFVPTKIEQIEAGTPGRLKVTAKSTNSEETIEDEFNTVLLAVGRDSC 296 Query: 254 T---KIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALD 310 T + V +E V T+VP +A GD+ + K + +G + A Sbjct: 297 TRTIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEGKLELTPVAIQAGRLLAQR 356 Query: 311 AE 312 Sbjct: 357 LY 358 >4NTC-A nrPDB Length = 335 Score = 122 bits (305), Expect = 2e-28, Method: Composition-based stats. Identities = 66/324 (20%), Positives = 112/324 (34%), Gaps = 23/324 (7%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 V IIG+GPA + A LAR ++++ + T + N G+ D Sbjct: 15 VDVLIIGAGPAGLSTATGLARQLHTAVVFDSGVYRNAK-------TQHMHNVLGW-DHRN 66 Query: 64 GSELMDRMREQST-KFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 +EL R T ++ T + + + +L+ + + ++LATG Sbjct: 67 PAELRAAGRADLTTRYSTIQFQNSTIEAIRQVETNQLFEARDNEGHSWYGRKVVLATGVR 126 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS-----ACEEAQFLTKYG 177 + + G W GI C CDG + + + V+ G A A+ + Sbjct: 127 DIPLDIEGYSECWANGIYHCLFCDGYEERGQ-ETVGVLALGPIANPARALHLARMALRLS 185 Query: 178 SKVFMLVRKDHLRASTIMQKRAEKNEKIE-ILYNTVALEAKGDGKLLNALRIKNTKKNEE 236 V + + A I Q E + + + G + + + + + Sbjct: 186 ESVTIYTNGNEQLAKEIQQAAEESPVGASGLKFEARPIRRFEKGDVAKTVIVHLGESESK 245 Query: 237 TDLPVSGLFYAIGHTPATKIVAGQVDTD--EAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 T+ G T A Q+ + E G I T P TSVPG FA GD Sbjct: 246 TE----GFLVYNPQTEVNGPFAKQLALNMTEGGDILTTPPFYETSVPGVFAVGDCAT-PL 300 Query: 295 RQAITSAGSGCMAALDAEKYLTSL 318 + + G +AA L + Sbjct: 301 KAVTPAVSMGSLAAGGLVAQLQAQ 324 >2NVK-X nrPDB Length = 488 Score = 122 bits (305), Expect = 3e-28, Method: Composition-based stats. Identities = 61/345 (17%), Positives = 109/345 (31%), Gaps = 50/345 (14%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 + +IG G A A + + + G + N P L Sbjct: 11 DLIVIGGGSAGLACAKEAVLNGARVACLDFVKPT-PTLGTKWGVGGTCVNVGCIPKKLMH 69 Query: 65 S-ELMDRMREQSTKFGTEI--------------------ITETVSKVDLSSKPFK----- 98 L+ ++ +G + V++VDL K + Sbjct: 70 QASLLGEAVHEAAAYGWNVDDKIKPDWHKLVQSVQNHIKSVNWVTRVDLRDKKVEYINGL 129 Query: 99 --------LWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVP 150 L + +T ++A G + +PG Y GI++ + ++ Sbjct: 130 GSFVDSHTLLAKLKSGERTITAQTFVIAVGGRPRYPDIPGAVEY---GITSDDLF--SLD 184 Query: 151 IFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA----STIMQKRAEKNEKIE 206 K L V+G G E A FL G + ++VR LR + + + I Sbjct: 185 REPGKTL-VVGAGYIGLECAGFLKGLGYEPTVMVRSIVLRGFDQQMAELVAASMEERGIP 243 Query: 207 ILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHT---PATKIVAGQVDT 263 L TV L + ++ KN + EE++ + +AIG + V Sbjct: 244 FLRKTVPLSVEKQDDGKLLVKYKNVETGEESEDVYDTVLWAIGRKGLVDDLNLPNAGVTV 303 Query: 264 DEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 + V T+V +A GD+ K + +G + A Sbjct: 304 QKDK--IPVDSQEATNVANIYAVGDIIYGKPELTPVAVLAGRLLA 346 >5U8W-A nrPDB Length = 481 Score = 120 bits (302), Expect = 6e-28, Method: Composition-based stats. Identities = 72/341 (21%), Positives = 111/341 (32%), Gaps = 45/341 (13%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMM--ANGIAAGGQLTTTTEIENFPGFPDGL 62 V +IG+GP + AAI A+ +K E + +A GG I + Sbjct: 9 DVVVIGAGPGGYVAAIRAAQLGLKTACIEKYIGKEGKVALGGTCLNVGCIPSKALLDSSY 68 Query: 63 TGSELMDRMREQ-STKFGTEI------------------------ITETVSKVDLSSKPF 97 E + + G I V+ + K Sbjct: 69 KYHEAKEAFKVHGIEAKGVTIDVPAMVARKANIVKNLTGGIATLFKANGVTSFEGHGKLL 128 Query: 98 ----KLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCD-GAVPIF 152 T + + + + +I+A+G+ + +P + + + AVP Sbjct: 129 ANKQVEVTGLDGKTQVLEAENVIIASGSRP--VEIPPAPLTDDIIVDSTGALEFQAVP-- 184 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLR--ASTIMQKRAEKNEKIEILYN 210 K L VIG G E + G++V +L D A + K A K + L Sbjct: 185 --KKLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQIAKEALKVLTKQGLNI 242 Query: 211 TVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAG 267 + + + T N E L A+G P T + V DE G Sbjct: 243 RLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRPVTTDLLAADSGVTLDERG 302 Query: 268 YIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 +I V TSVPG FA GDV A ++ G M A Sbjct: 303 FIY-VDDHCKTSVPGVFAIGDVVRGAM-LAHKASEEGVMVA 341 Score = 35.3 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 52/308 (16%), Positives = 87/308 (28%), Gaps = 54/308 (17%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 K+ +IG+G AR + + E + AA Q+ Sbjct: 186 KLGVIGAGVIGLELGSVWARLGAEVTVLEALDKFLPAADEQI-----------------A 228 Query: 65 SELMDRMREQSTKFGTEIITE-TVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 E + + +Q G I V+ ++ K + + T D +I+A G Sbjct: 229 KEALKVLTKQ----GLNIRLGARVTASEVKKKQVTVTFTDANGEQKETFDKLIVAVGRRP 284 Query: 124 KRMHL----PGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK 179 L G + I C +VP V GD A K + Sbjct: 285 VTTDLLAADSGVTLDERGFIYVDDHCKTSVP-------GVFAIGDV-VRGAMLAHKASEE 336 Query: 180 VFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDL 239 M+ A I +A+ N Y+ + ++ + + T L Sbjct: 337 GVMV-------AERIAGHKAQMN------YDLIPSVIYTHPEIAWVGKTEQT-------L 376 Query: 240 PVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAIT 299 G+ +G P D G +K + + V G G +Q Sbjct: 377 KAEGVEVNVGTFPFAASGRAMAANDTTGLVKVIADAKTDRVLGVHVIGPSAAELVQQGAI 436 Query: 300 SAGSGCMA 307 G A Sbjct: 437 GMEFGTSA 444 >1NHQ-A nrPDB Length = 447 Score = 119 bits (299), Expect = 1e-27, Method: Composition-based stats. Identities = 64/333 (19%), Positives = 113/333 (33%), Gaps = 43/333 (12%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG-----IAAGGQLTTTTEIENFPGFP 59 KV ++GS + A L + P G +++G QL ++++ Sbjct: 2 KVIVLGSSHGGYEAVEEL--LNLHPDAEIQWYEKGDFISFLSSGMQLYLEGKVKDVNSVR 59 Query: 60 DGLTGSELMDRMREQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 +TG E+ G + + T ++ + + + + D +I++ Sbjct: 60 -YMTG--------EKMESRGVNVFSNTEITAIQPKEHQVTVKDLVSGEERVENYDKLIIS 110 Query: 119 TGASAKRMHLPGEET---YWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTK 175 GA + +PG++ Y +G + VIG G E A+ K Sbjct: 111 PGAVPFELDIPGKDLDNIYLMRGRQWAIKLKQKTVDPEVNNVVVIGSGYIGIEAAEAFAK 170 Query: 176 YGSKVFMLVRKDHLRASTIMQK------RAEKNEKIEILYNTVALEAKGDGKLLNALRIK 229 G KV ++ D + ++ + I I +GDG++ + K Sbjct: 171 AGKKVTVIDILDRPLGVYLDKEFTDVLTEEMEANNITIATGETVERYEGDGRVQKVVTDK 230 Query: 230 NTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDV 289 N + A+G P T + G ++ G IKT TS P FA GD Sbjct: 231 NAY-------DADLVVVAVGVRPNTAWLKGTLELHPNGLIKT-DEYMRTSEPDVFAVGDA 282 Query: 290 QDSKY---------RQAITSAGSGCMAALDAEK 313 KY A + G A + E+ Sbjct: 283 TLIKYNPADTEVNIALATNARKQGRFAVKNLEE 315 Score = 41.1 bits (95), Expect = 6e-04, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 46/137 (33%), Gaps = 25/137 (18%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 N V +IGSG AA A+A K + + + G L Sbjct: 150 NNVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDR---PLGVYLD---------------- 190 Query: 64 GSELMDRMREQSTKFGTEIIT-ETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 E D + E+ I T ETV + + + K+ T+ N D +++A G Sbjct: 191 -KEFTDVLTEEMEANNITIATGETVERYEGDGRVQKVVTDKN----AYDADLVVVAVGVR 245 Query: 123 AKRMHLPGEETYWQKGI 139 L G G+ Sbjct: 246 PNTAWLKGTLELHPNGL 262 >6AON-A nrPDB Length = 478 Score = 119 bits (298), Expect = 2e-27, Method: Composition-based stats. Identities = 73/340 (21%), Positives = 112/340 (32%), Gaps = 61/340 (17%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMM--ANGIAAGGQLTTTTEIENFPGFP 59 V +IG+GP + AAI A+ + + G A GG T I + Sbjct: 6 KQFDVVVIGAGPGGYIAAIRAAQLGMSVACIDAWQNGQGGPAPGGTCTNVGCIPSKA--- 62 Query: 60 DGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVT-------- 111 L SE ++ + G E+ K+D + N D Sbjct: 63 -LLQSSEHYEQANHHFAEHGIEVK-GVSLKLDTLIGRKNTVVKQNNDGILYLFKKNKVTY 120 Query: 112 ----------------------------TDAIILATGASAKR-MHLPGEETYWQKGISAC 142 +I+ATG+SA+ LP +E A Sbjct: 121 FHGKGAFAGQVDGGWSIKVTGTTDADLVAKHVIVATGSSARELPGLPFDEKNILSNDGAL 180 Query: 143 AVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK----- 197 + GAVP K L VIG G E + G++V +L A+ Q Sbjct: 181 NI--GAVP----KKLGVIGAGVIGLEMGSVWRRLGAEVTILEAMPEFLAAADQQVAKEAL 234 Query: 198 RAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV 257 ++ + ++I E K K + + K E L V L +IG P T + Sbjct: 235 KSFAKQGLDIQTGVKIGEIKAAAKSITVPYVD--AKGAEQKLVVDKLIVSIGRVPYTGGL 292 Query: 258 AG---QVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 + DE G++ V T++P +A GDV Sbjct: 293 NAEAVGLKLDERGFV-AVDEDCKTNLPNVWAVGDVVRGPM 331 >3LAD-A nrPDB Length = 476 Score = 116 bits (291), Expect = 1e-26, Method: Composition-based stats. Identities = 73/341 (21%), Positives = 114/341 (33%), Gaps = 45/341 (13%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEG--MMANGIAAGG------------------ 44 V +IG+GP + AAI A+ +K L E A GG Sbjct: 5 DVIVIGAGPGGYVAAIKSAQLGLKTALIEKYKGKEGKTALGGTCLNVGCIPSKALLDSSY 64 Query: 45 QLTTTTEIENFPGFPDGLTGSEL--MDRMREQSTK--FGTEIITETVSKVDLSSKPFKLW 100 + E G G ++ M ++Q + G + V L KL Sbjct: 65 KFHEAHESFKLHGISTGEVAIDVPTMIARKDQIVRNLTGGVASLIKANGVTLFEGHGKLL 124 Query: 101 TEFNEDA-------EPVTTDAIILATGASA-KRMHLPGEETYWQKGISACAVCDGAVPIF 152 + + + T+ +ILA+G+ + P ++ + + Sbjct: 125 AGKKVEVTAADGSSQVLDTENVILASGSKPVEIPPAPVDQD-----VIVDSTGALDFQNV 179 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ--KRAEKNEKIEILYN 210 K L VIG G E + G++V +L D + Q K A+K + L Sbjct: 180 PGK-LGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKI 238 Query: 211 TVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAG 267 + G + +K E L A+G P T + V DE G Sbjct: 239 LLGARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPVTTDLLAADSGVTLDERG 298 Query: 268 YIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 +I V TSVPG +A GDV A ++ G + A Sbjct: 299 FIY-VDDYCATSVPGVYAIGDVVRGAM-LAHKASEEGVVVA 337 Score = 41.5 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 54/307 (17%), Positives = 88/307 (28%), Gaps = 52/307 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 K+ +IG+G AR + + E M A Q+ Sbjct: 182 KLGVIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQV-----------------A 224 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 E + +Q K ++ V+ ++ +K + E + D +I+A G Sbjct: 225 KEAQKILTKQGLKI---LLGARVTGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRRPV 281 Query: 125 RMHL----PGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 L G + I C +VP V GD A K + Sbjct: 282 TTDLLAADSGVTLDERGFIYVDDYCATSVP-------GVYAIGDV-VRGAMLAHKASEEG 333 Query: 181 FMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLP 240 ++ A I +A+ N + E G GK E L Sbjct: 334 VVV-------AERIAGHKAQMNYDLIPAVIYTHPEIAGVGKT-------------EQALK 373 Query: 241 VSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITS 300 G+ +G P D AG++K + + V G G +Q + Sbjct: 374 AEGVAINVGVFPFAASGRAMAANDTAGFVKVIADAKTDRVLGVHVIGPSAAELVQQGAIA 433 Query: 301 AGSGCMA 307 G A Sbjct: 434 MEFGTSA 440 >1ZK7-A nrPDB Length = 467 Score = 116 bits (290), Expect = 2e-26, Method: Composition-based stats. Identities = 65/219 (29%), Positives = 86/219 (39%), Gaps = 27/219 (12%) Query: 86 TVSKVDLSSKPFKLWTEFNEDAEPVTT-DAIILATGASAKRMHLPG--EETYWQKGISAC 142 V L NE E V D ++ATGAS +PG E YW S Sbjct: 112 VVHGEARFKDDQSLTVRLNEGGERVVMFDRCLVATGASPAVPPIPGLKESPYW---TSTE 168 Query: 143 AVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD-HLRASTIMQK---R 198 A+ +P + LAVIG A E AQ + GSKV +L R R + + Sbjct: 169 ALASDTIP----ERLAVIGSSVVALELAQAFARLGSKVTVLARNTLFFREDPAIGEAVTA 224 Query: 199 AEKNEKIEILYNTVALEA-KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV 257 A + E IE+L +T A + DG+ + +L L A G TP T+ + Sbjct: 225 AFRAEGIEVLEHTQASQVAHMDGEFV--------LTTTHGELRADKLLVATGRTPNTRSL 276 Query: 258 ---AGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSK 293 A V + G I G TS P +AAGD D Sbjct: 277 ALDAAGVTVNAQGAIVIDQG-MRTSNPNIYAAGDCTDQP 314 >4YWO-A nrPDB Length = 462 Score = 115 bits (287), Expect = 3e-26, Method: Composition-based stats. Identities = 73/332 (21%), Positives = 126/332 (37%), Gaps = 43/332 (12%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGM------MANGIAAGGQLTTTTEIEN--- 54 +K+ IIG G A A I +KP+L + G ++ EI Sbjct: 16 HKLAIIGYGAAGFAAMIKANELGVKPVLIGKGEIGGTCVNVGCVPSKRMLYIAEIYKKAR 75 Query: 55 -------FPGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDA 107 +P F L+ MR+ TK+ + V + ++ F + Sbjct: 76 EVTGSEVYPPFSSFQEKDGLVQEMRK--TKYEDLLSYYDVELIQGEAR-FISPHAVKVNG 132 Query: 108 EPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSAC 167 + + + ++ATG+S +PG + + + P R LAVIGG A Sbjct: 133 QVIEAEKFVIATGSSPLIPRIPGLDK-----VGFWTNREALSPDRRIDSLAVIGGRALAL 187 Query: 168 EEAQFLTKYGSKVFMLVRKDHLRAS-----TIMQKRAEKNEKIEILYNTVALEA-KGDGK 221 E AQ ++ +V +L R L ++ +R +N+ + ++ E KG GK Sbjct: 188 EFAQMYSRMKVEVAILQRSPVLIPDWEPEASVEARRIMENDGVAVVTGVNVKEVRKGAGK 247 Query: 222 LLNALRIKNTKKNEETDLPVSGLFYAIGHTPA--TKIVAGQVDTDEAGYIKTVPGSSLTS 279 ++ ++ ++ + A G P + V +E G IK V T Sbjct: 248 IVIT---------DKGEVEADEILLATGRKPNVDLGLENAGVRLNERGGIK-VDDELRTD 297 Query: 280 VPGFFAAGDVQDSKYRQAITSAGSGCMAALDA 311 P +AAGDV K +A+ + G +A +A Sbjct: 298 NPHIYAAGDVLGGKMLEAL-AGRQGSIATENA 328 >2CFY-A nrPDB Length = 521 Score = 114 bits (286), Expect = 4e-26, Method: Composition-based stats. Identities = 47/243 (19%), Positives = 92/243 (37%), Gaps = 17/243 (6%) Query: 81 EIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGIS 140 +++ E + K ++ + + + ++ATG + + +PG++ Y IS Sbjct: 146 KVVYENAYGQFIGPHRIKATNNKGKE-KIYSAERFLIATGERPRYLGIPGDKEYC---IS 201 Query: 141 ACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-STIMQKR- 198 + + ++P K L V+G A E A FL G V ++VR LR M + Sbjct: 202 SDDLF--SLPYCPGKTL-VVGASYVALECAGFLAGIGLDVTVMVRSILLRGFDQDMANKI 258 Query: 199 --AEKNEKIEILYNTVAL---EAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA 253 + I+ + V + + + + ++T E + + + AIG Sbjct: 259 GEHMEEHGIKFIRQFVPIKVEQIEAGTPGRLRVVAQSTNSEEIIEGEYNTVMLAIGRDAC 318 Query: 254 T---KIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALD 310 T + V +E V T+VP +A GD+ + K + +G + A Sbjct: 319 TRKIGLETVGVKINEKTGKIPVTDEEQTNVPYIYAIGDILEDKVELTPVAIQAGRLLAQR 378 Query: 311 AEK 313 Sbjct: 379 LYA 381 >2YQU-A nrPDB Length = 455 Score = 113 bits (284), Expect = 8e-26, Method: Composition-based stats. Identities = 72/333 (21%), Positives = 122/333 (36%), Gaps = 43/333 (12%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG--------IAAGGQLTTTTEIENFP 56 + +IG+GP + AAI A+ +K + E A G I + L TT I Sbjct: 3 DLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYEAK 62 Query: 57 -GFPDG-LTGSEL-MDRMREQSTKF------GTEIITETVSKVDLSSKPFKLWTEFN--- 104 G + G EL + + K G E + + + + + +E Sbjct: 63 KGLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKK-NGIARHQGTARFLSERKVLV 121 Query: 105 -EDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGG 163 E E + I++ATG++ + Y + S A+ VP K L V+GGG Sbjct: 122 EETGEELEARYILIATGSAPLIPPWAQVD-YERVVTSTEALSFPEVP----KRLIVVGGG 176 Query: 164 DSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ-----KRAEKNEKIEILYNTVALEAKG 218 E + G++V +L D + + ++ +R K + + I Sbjct: 177 VIGLELGVVWHRLGAEVIVLEYMDRILPTMDLEVSRAAERVFKKQGLTIRTGVRVTAVVP 236 Query: 219 DGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTVPGS 275 + K + ++ + L + A+G P T+ + + TDE G I V Sbjct: 237 EAKG-ARVELEGGE-----VLEADRVLVAVGRRPYTEGLSLENAGLSTDERGRIP-VDEH 289 Query: 276 SLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 T VP +A GDV A ++ G A Sbjct: 290 LRTRVPHIYAIGDVVRGPM-LAHKASEEGIAAV 321 >6B4O-A nrPDB Length = 452 Score = 113 bits (283), Expect = 1e-25, Method: Composition-based stats. Identities = 55/322 (17%), Positives = 99/322 (30%), Gaps = 67/322 (20%) Query: 22 LARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT--GSELMDRMREQSTKFG 79 +L EG G N P + S +M+ M + +G Sbjct: 25 AGMHGANVLLIEGNEIGGTCV-----------NVGCVPKKVMWQASSMMEMMERDTAGYG 73 Query: 80 TEII---TETVSKVDLSSK-------------------------PFKLWTEFNEDAEPVT 111 ++ V+ K F + T Sbjct: 74 FDVEIKNFSFKQLVENREKYIDFLHGAYNRGLDSNNIERIHGYATFTGEQTIEVNGTEYT 133 Query: 112 TDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQ 171 I++ATG K++ +PGEE +P K + +G G A E A Sbjct: 134 APHILIATGGRPKKLGIPGEEYALDSNGF---FALEEMP----KRVVFVGAGYIAAELAG 186 Query: 172 FLTKYGSKVFMLVRK-------DHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLN 224 L G++ R D + + ++++ + ++I N + + + Sbjct: 187 TLHGLGAETHWAFRHERPLRSFDDMLSEKVVER--YQEMGMQIHPNATPAKIEKTAQNEY 244 Query: 225 ALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKTVPGSSLTSVP 281 + +N + + + + G P T + +V DE GY+K V T+ Sbjct: 245 VITFENGES-----ITTDAVIFGTGRQPNTDQLGLENTKVALDEKGYVK-VDKFQNTTQN 298 Query: 282 GFFAAGDVQDS-KYRQAITSAG 302 G +A GDV +AG Sbjct: 299 GIYAVGDVIGKIDLTPVAIAAG 320 >2EQ6-A nrPDB Length = 464 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 78/338 (23%), Positives = 127/338 (37%), Gaps = 37/338 (10%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAA-------------GGQLT 47 M + +IG+GP + AAI A+ +K + E G+ L Sbjct: 4 MKTYDLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGEVGGVCLNVGCIPTKALLHAAETLH 63 Query: 48 TTTEIENFPGFPDGLTGSELMDRMREQSTK-----FGTEIITETVSKVDLSSKPFKLWTE 102 E F + + R+Q K GT + V + ++ E Sbjct: 64 HLKVAEGFGLKAKPELDLKKLGGWRDQVVKKLTGGVGTLLKGNGVELLRGFARLVGP-KE 122 Query: 103 FNEDAEPVTTDAIILATGASAKRM-HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIG 161 E ++ILATG+ + P E W A V +G K L VIG Sbjct: 123 VEVGGERYGAKSLILATGSEPLELKGFPFGEDVWD-STRALKVEEGL-----PKRLLVIG 176 Query: 162 GGDSACEEAQFLTKYGSKVFMLVRKDHLRAS-----TIMQKRAEKNEKIEILYNTVALEA 216 GG E Q + G++V ++ + + +RA + E I + T A+ Sbjct: 177 GGAVGLELGQVYRRLGAEVTLIEYMPEILPQGDPETAALLRRALEKEGIRVRTKTKAVGY 236 Query: 217 KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVAGQVDTDEAGYIKTVP 273 + L+ +R++ + E ++ V + A+G P T+ + V DE G+I+ V Sbjct: 237 EKKKDGLH-VRLEPAEGGEGEEVVVDKVLVAVGRKPRTEGLGLEKAGVKVDERGFIR-VN 294 Query: 274 GSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDA 311 TSVPG +A GD A + G +AA +A Sbjct: 295 ARMETSVPGVYAIGDAARPPL-LAHKAMREGLIAAENA 331 >5ER0-A nrPDB Length = 518 Score = 113 bits (282), Expect = 1e-25, Method: Composition-based stats. Identities = 56/300 (18%), Positives = 97/300 (32%), Gaps = 26/300 (8%) Query: 5 KVTIIGSGPAAHTA--AIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 KVT++G A A I + + +YE + G I + G Sbjct: 52 KVTVVGCTHAGTFAIKQILAEHPDAEVTVYERNDVISFLSCG-------IALYLG-GKVA 103 Query: 63 TGSELMDRMREQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 L E+ K G + V +D K + N + D +++ +G+ Sbjct: 104 DPQGLFYSSPEELQKLGANVQMNHNVLAIDPDQKTVTVEDLTNHAQTTESYDKLVMTSGS 163 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRN-KPLAVIGGGDSACEEAQFLTKYGSKV 180 +PG ++ K A + + K + VIG G E A+ + G V Sbjct: 164 WPIVPKIPGIDSDRVKLCKNWAHAQALIEDAKEAKRITVIGAGYIGAELAEAYSTTGHDV 223 Query: 181 FMLVRKDHLRASTI------MQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKN 234 ++ + + ++ ++ +++ L KN+ Sbjct: 224 TLIDAMARVMPKYFDADFTDVIEQDYRDHGVQLALGETVESFTDSATGLTIKTDKNSY-- 281 Query: 235 EETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 IG P T ++ G+VD G I T +S P FAAGD Y Sbjct: 282 -----ETDLAILCIGFRPNTDLLKGKVDMAPNGAIIT-DDYMRSSNPDIFAAGDSAAVHY 335 >3URH-A nrPDB Length = 491 Score = 112 bits (281), Expect = 2e-25, Method: Composition-based stats. Identities = 59/328 (17%), Positives = 110/328 (33%), Gaps = 40/328 (12%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGM-------MANGIAAGGQLTTTTEIE 53 M+ + +IGSGP + AI A+ +K + E + G L +E+ Sbjct: 23 MMAYDLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMF 82 Query: 54 NFPGFPDGLTGSELMD---RMREQSTKFGTEIITETVSKVDLSSKPFKL----------- 99 + G E+ + +++ + + V V K K+ Sbjct: 83 HQAQHGLEALGVEVANPKLNLQKMMAHKDATVKSN-VDGVSFLFKKNKIDGFQGTGKVLG 141 Query: 100 -----WTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRN 154 T + + + +++ATG+ +PG E + + + A+ Sbjct: 142 QGKVSVTNEKGEEQVLEAKNVVIATGSD--VAGIPGVEVAFDEKTIVSSTGALALEKVPA 199 Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ-----KRAEKNEKIEILY 209 + V+GGG E + G+KV ++ D + + +R + I+ Sbjct: 200 S-MIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILGGMDGEVAKQLQRMLTKQGIDFKL 258 Query: 210 NTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEA 266 A G + + K E T L + A G P+T + V D Sbjct: 259 GAKVTGAVKSGDG-AKVTFEPVKGGEATTLDAEVVLIATGRKPSTDGLGLAKAGVVLDSR 317 Query: 267 GYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 G ++ TS+ G +A GDV Sbjct: 318 GRVEI-DRHFQTSIAGVYAIGDVVRGPM 344 >1EBD-A nrPDB Length = 455 Score = 112 bits (280), Expect = 2e-25, Method: Composition-based stats. Identities = 65/340 (19%), Positives = 117/340 (34%), Gaps = 41/340 (12%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGM------MANGIAAGGQLTTTTEIENF 55 + + ++G+GP + AAI A+ K + E + G L + + Sbjct: 2 IETETLVVGAGPGGYVAAIRAAQLGQKVTIVEKGNLGGVCLNVGCIPSKALISASHRYEQ 61 Query: 56 PGFPD--GLTGS--------------ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKL 99 + G+ ++ ++ E V + Sbjct: 62 AKHSEEMGIKAENVTIDFAKVQEWKASVVKKLTGGVEGLLKGNKVEIVKGEAYFVDANTV 121 Query: 100 WTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAV 159 + A+ T I+ATG+ + LP + + S A+ G VP K L V Sbjct: 122 RVVNGDSAQTYTFKNAIIATGSRP--IELPNFKFSNRILDSTGALNLGEVP----KSLVV 175 Query: 160 IGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAS-----TIMQKRAEKNEKIEILYNTVAL 214 IGGG E +G+KV +L + + + K+ K + +E++ N + Sbjct: 176 IGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKGVEVVTNAL-- 233 Query: 215 EAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKT 271 AKG + + + + E + + +G P T + + G I+ Sbjct: 234 -AKGAEEREDGVTVTYEANGETKTIDADYVLVTVGRRPNTDELGLEQIGIKMTNRGLIE- 291 Query: 272 VPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDA 311 V TSVP FA GD+ A ++ G +AA Sbjct: 292 VDQQCRTSVPNIFAIGDIVPGPA-LAHKASYEGKVAAEAI 330 >5X1Y-B nrPDB Length = 554 Score = 110 bits (275), Expect = 9e-25, Method: Composition-based stats. Identities = 66/335 (19%), Positives = 114/335 (34%), Gaps = 53/335 (15%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGM------------MANGIAAGGQLTTTTEI 52 + IIGSG AA ++AI K + E + + G++ ++ Sbjct: 86 DLLIIGSGAAAFSSAIKAIEYGAKVGMIERGTVGGTCVNIGCVPSKTLLRAGEIIHLSKD 145 Query: 53 ENFPGF---------PDGLTGSE-LMDRMREQ-----STKFGTEIITETVSKVDLSSKPF 97 F G +T + L+ +R Q ++ ++I VD S+ Sbjct: 146 NPFIGLQTSAGEVDLASLITQKDKLVSELRNQKYMDLIDEYNFDLIKGEAKFVDASTVEV 205 Query: 98 KLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPL 157 + ++ ++ATGAS + G E S + +P K L Sbjct: 206 --------NGAKLSAKRFLIATGASPSLPQISGLEK-MDYLTSTTLLELKKIP----KRL 252 Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAST-----IMQKRAEKNEKIEILYNTV 212 VIG G E Q GS++ ++ R + L ++A + I ++ Sbjct: 253 TVIGSGYIGMELGQLFHHLGSEITLMQRSERLLKEYDPEISESVEKALIEQGINLVKGAT 312 Query: 213 ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYI 269 + G++ R+ T + L A G P T + A V+T + I Sbjct: 313 FERVEQSGEIK---RVYVTVNGSREVIESDQLLVATGRKPNTDSLNLSAAGVETGKNNEI 369 Query: 270 KTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSG 304 TS +AAGDV + +A G Sbjct: 370 LI-NDFGQTSNEKIYAAGDVTLGP-QFVYVAAYEG 402 >6BZ0-A nrPDB Length = 480 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 59/344 (17%), Positives = 110/344 (31%), Gaps = 44/344 (12%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG-IAAGGQLTTTTEIENFPGFPDGLT 63 + +IG GP + AAI A+ K E + NG + GG I + Sbjct: 9 DLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNGKPSLGGTCLNVGCIPSKALLDSSHR 68 Query: 64 GSELMDRMREQSTKFG----------------TEIITETV------SKVDLSSKPFKLWT 101 + + + + G + +T + + ++ KL Sbjct: 69 YEDTVHHLADHGITTGEVNFDLAKLLARKDKIVDQLTGGIDQLLKGNGIEWLKGTGKLLA 128 Query: 102 EFN-------EDAEPVTTDAIILATGASAKRMHL-PGEETYWQKGISACAVCDGAVPIFR 153 + + + +ILA+G+ + + P ++ A + Sbjct: 129 GKKVEFVPHEGETQILEPKYVILASGSVPVNIPVAPVDQDIIVDSTGALNFPE------V 182 Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL--RASTIMQKRAEKNEKIEILYNT 211 K L VIG G E + G++V + D A + K +K + L Sbjct: 183 PKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMDAFLPMADKALSKEYQKILTKQGLDIR 242 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGY 268 + + G + +K T+ E+ + L +G + + + E G Sbjct: 243 IGAKVSGTEVNGREVTVKYTQAGEDKEQTFDKLIVCVGRKAYAEGLLAEDSGIKLTERGL 302 Query: 269 IKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAE 312 ++ V TSV G +A GD+ A + G MA Sbjct: 303 VE-VNDHCATSVEGVYAIGDLVRGPM-LAHKAMEEGVMAVERIH 344 >2CDU-A nrPDB Length = 452 Score = 110 bits (274), Expect = 1e-24, Method: Composition-based stats. Identities = 42/234 (17%), Positives = 89/234 (38%), Gaps = 23/234 (9%) Query: 73 EQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGE 131 E+ + G + V+ VD +K K+ + + D +I+ TG+ +PG Sbjct: 66 EELSNLGANVQMRHQVTNVDPETKTIKVKDLITNEEKTEAYDKLIMTTGSKPTVPPIPGI 125 Query: 132 ETYWQKGISACAVCDGAVPIF----RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 ++ + C + A +F + K + +IG G E A+ + V ++ + Sbjct: 126 DSSR---VYLCKNYNDAKKLFEEAPKAKTITIIGSGYIGAELAEAYSNQNYNVNLIDGHE 182 Query: 188 HLRASTIMQK------RAEKNEKIEILYNTVALEAKG-DGKLLNALRIKNTKKNEETDLP 240 + ++ + + + ++ + + D +++ TK + ++ Sbjct: 183 RVLYKYFDKEFTDILAKDYEAHGVNLVLGSKVAAFEEVDDEII-------TKTLDGKEIK 235 Query: 241 VSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 IG P T+++ G+V + G I T +S FAAGD Y Sbjct: 236 SDIAILCIGFRPNTELLKGKVAMLDNGAIIT-DEYMHSSNRDIFAAGDSAAVHY 288 >5J5Z-A nrPDB Length = 496 Score = 108 bits (271), Expect = 3e-24, Method: Composition-based stats. Identities = 64/329 (19%), Positives = 111/329 (33%), Gaps = 43/329 (13%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG--------IAAGGQLTTTTEIE 53 + VT+IGSGP + AAI A+ K + E G I + L + Sbjct: 27 IDADVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGGTCLNVGCIPSKALLNNSHYYH 86 Query: 54 NFPGFPDGLTGSELMD------RMREQ------STKFGTEIITETVSKV------DLSSK 95 G G E+ + +M EQ + G + + V ++ K Sbjct: 87 MAHGKDFASRGIEMSEVRLNLDKMMEQKSTAVKALTGGIAHLFKQNKVVHVNGYGKITGK 146 Query: 96 PFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR-N 154 T+ + + + T I++ATG+ + PG +S+ GA+ + + Sbjct: 147 NQVTATKADGGTQVIDTKNILIATGS--EVTPFPGITIDEDTIVSST----GALSLKKVP 200 Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK------RAEKNEKIEIL 208 + + VIG G E + G+ V + H+ I + R + + + Sbjct: 201 EKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGGVGIDMEISKNFQRILQKQGFKFK 260 Query: 209 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP---ATKIVAGQVDTDE 265 NT A + I+ + + L IG P + ++ D Sbjct: 261 LNTKVTGATKKSDGKIDVSIEAASGGKAEVITCDVLLVCIGRRPFTKNLGLEELGIELDP 320 Query: 266 AGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 G I V T +P +A GDV Sbjct: 321 RGRIP-VNTRFQTKIPNIYAIGDVVAGPM 348 >5W1J-A nrPDB Length = 584 Score = 108 bits (269), Expect = 5e-24, Method: Composition-based stats. Identities = 50/223 (22%), Positives = 84/223 (37%), Gaps = 22/223 (9%) Query: 100 WTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAV 159 T + +TT+ II+ATG + +PG + Y GI++ + + K L V Sbjct: 232 TTNKQGIVKNITTNTIIVATGERPRYPPIPGAKEY---GITSDDLF--TLDHNPGKTLCV 286 Query: 160 IGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRA------EKNEKIEILYNTVA 213 G + E A FL+ G V ++VR LR Q+ A ++ + V Sbjct: 287 -GASYVSLECAGFLSSIGCDVTVMVRSIFLRG--FDQQMAGLISDYIAKYGVKFVRPCVP 343 Query: 214 ------LEAKGDGKLLNALRIK-NTKKNEETDLPVSGLFYAIGHTP-ATKIVAGQVDTDE 265 E + L ++ + + + +A+G P T I VD Sbjct: 344 TSVRCLEEYDPESGKLAIYEVEGKHEDGTPFKDTFNTVLFAVGRDPCTTNIGLQNVDVKT 403 Query: 266 AGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 V T+VP +A GDV ++ Y+ + +G A Sbjct: 404 TNGRVVVDDEERTNVPNIYAIGDVSNAGYQLTPLAIQAGKNLA 446 >4JDR-A nrPDB Length = 474 Score = 106 bits (266), Expect = 8e-24, Method: Composition-based stats. Identities = 68/340 (20%), Positives = 118/340 (34%), Gaps = 45/340 (13%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG--------IAAGGQLTTTTEIE 53 + +V ++G+GPA ++AA A ++ ++ E G I + L IE Sbjct: 5 IKTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIE 64 Query: 54 NFPGFPD----GLTGSELMDRMREQSTKFGTEIITE-----------TVSKVDLSSKPFK 98 + +D++R K ++ V+ + + Sbjct: 65 EAKALAEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGANT 124 Query: 99 LWTEFNEDAEPVTTDAIILATGASAKRMH-LPGEETYWQKGISACAVCDGAVPIFRNKPL 157 L E + D I+A G+ ++ +P E+ D + L Sbjct: 125 LEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDST------DALELKEVPERL 178 Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAS------TIMQKRAEKNEKIEILYNT 211 V+GGG E GS++ ++ D + + + KR K + + Sbjct: 179 LVMGGGIIGLEMGTVYHALGSQIDVVEMFDQVIPAADKDIVKVFTKRISKKFNLMLETKV 238 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGY 268 A+EAK DG + KK + AIG P K + V+ D+ G+ Sbjct: 239 TAVEAKEDGIYVTM----EGKKAPAEPQRYDAVLVAIGRVPNGKNLDAGKAGVEVDDRGF 294 Query: 269 IKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 I+ V T+VP FA GD+ A G +AA Sbjct: 295 IR-VDKQLRTNVPHIFAIGDIVGQPM-LAHKGVHEGHVAA 332 >2WOV-A nrPDB Length = 495 Score = 106 bits (265), Expect = 1e-23, Method: Composition-based stats. Identities = 71/359 (19%), Positives = 117/359 (32%), Gaps = 73/359 (20%) Query: 5 KVTIIGSGPAAHTAAIYLA-RAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD--G 61 + +IG+G A A + + + ++G L T N P Sbjct: 9 DLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAALGGTCV--NVGCVPKKLM 66 Query: 62 LTGSELMDRMREQSTKFGTEIITETV------------SKVDLSSKPFKLWTEFNED--- 106 +TG++ MD +RE + FG E +V V +K ++ E Sbjct: 67 VTGAQYMDHLRESA-GFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTEGLDF 125 Query: 107 -------------------------AEPVTTDAIILATGASAKRMHLPGEETYWQKGISA 141 E + D I+LATG+ + +PG E Sbjct: 126 FLGWGSLESKNVVVVRETADPKSAVKERLQADHILLATGSWPQMPAIPGIE-------HC 178 Query: 142 CAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKY---GSKVFMLVRKDHLR-----AST 193 + + + + +GGG + E A Y G KV + R + + Sbjct: 179 ISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPPGGKVTLCYRNNLILRGFDETIR 238 Query: 194 IMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA 253 + IEI+ N + + + ++ K L V + AIG P Sbjct: 239 EEVTKQLTANGIEIMTNENPAKVSLNTDGSKHVTFESGKT-----LDVDVVMMAIGRIPR 293 Query: 254 TKIVAGQ---VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAAL 309 T + V G ++ V S T+VP +A GD+ D R +T AAL Sbjct: 294 TNDLQLGNVGVKLTPKGGVQ-VDEFSRTNVPNIYAIGDITD---RLMLTPVAINEGAAL 348 >3ICS-A nrPDB Length = 588 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 51/254 (20%), Positives = 95/254 (37%), Gaps = 26/254 (10%) Query: 57 GFPDGLTG------SELMDRMREQSTKFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEP 109 G P + G L+ + S +F +I + V K++ K + + Sbjct: 79 GLPYYIGGVITERQKLLVQTVERMSKRFNLDIRVLSEVVKINKEEKTITIKNVTTNETYN 138 Query: 110 VTTDAIILATGASAKRMHLPGEET----YWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 D +IL+ GA +PG E + + + + + + VIGGG Sbjct: 139 EAYDVLILSPGAKPIVPSIPGIEEAKALFTLRNVPDTDRIKAYIDEKKPRHATVIGGGFI 198 Query: 166 ACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAE-----KNEKIEILYNTVALEAKGDG 220 E + L + G +V ++ + + + A KN +E+++ + +G Sbjct: 199 GVEMVENLRERGIEVTLVEMANQVMPPIDYEMAAYVHEHMKNHDVELVFEDGVDALEENG 258 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG-QVDTDEAGYIKTVPGSSLTS 279 + +R+K+ + + L AIG P + + G + G IK V TS Sbjct: 259 AV---VRLKSG-----SVIQTDMLILAIGVQPESSLAKGAGLALGVRGTIK-VNEKFQTS 309 Query: 280 VPGFFAAGDVQDSK 293 P +A GD + K Sbjct: 310 DPHIYAIGDAIEVK 323 >3IWA-A nrPDB Length = 472 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 54/314 (17%), Positives = 109/314 (34%), Gaps = 46/314 (14%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V +IG+ AA R + + + A+ I+ GG G P ++G Sbjct: 6 VVVIGAVALGPKAACRFKRLDPEAHVTMIDQASRISYGG-----------CGIPYYVSG- 53 Query: 66 ELMDRMREQSTKFGTE--------------IITETVSKVDLSSKPFKLWTEFNEDAEPVT 111 E+ + Q+T + ++ +D ++ ++ + + Sbjct: 54 EVSNIESLQATPYNVVRDPEFFRINKDVEALVETRAHAIDRAAHTVEIENLRTGERRTLK 113 Query: 112 TDAIILATGASAKRMHLPGEETYWQKGISACA---VCDGAVPIFRNKPLAVIGGGDSACE 168 D ++LA G+ A R + G + ++ A+ ++GGG E Sbjct: 114 YDKLVLALGSKANRPPVEGMDLAGVTPVTNLDEAEFVQHAISAGEVSKAVIVGGGFIGLE 173 Query: 169 EAQFLTK-YGSKVFMLVRKDHLRA-------STIMQKRAEKNEKIEILYNTVALEAKGDG 220 A L +G ++ D + S +++ EKN+ + + + +G+ Sbjct: 174 MAVSLADMWGIDTTVVELADQIMPGFTSKSLSQMLRHDLEKNDVV-VHTGEKVVRLEGEN 232 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG-QVDTDEAGYIKTVPGSSLTS 279 + + ++ L + A G +P T++ ++ D G I V TS Sbjct: 233 GKVARVI------TDKRTLDADLVILAAGVSPNTQLARDAGLELDPRGAI-IVDTRMRTS 285 Query: 280 VPGFFAAGDVQDSK 293 P FA GD Sbjct: 286 DPDIFAGGDCVTIP 299 >6CMZ-A nrPDB Length = 466 Score = 102 bits (254), Expect = 2e-22, Method: Composition-based stats. Identities = 59/342 (17%), Positives = 99/342 (28%), Gaps = 53/342 (15%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG-------IAAGGQLTTTTEIENF 55 H + +IG GP + AAI + I +L E G I + + E Sbjct: 8 HTTLLVIGGGPGGYVAAIRAGQLGIPTVLVERDRLGGTCLNIGCIPSKALIHVADAFEQA 67 Query: 56 PGFP-DGLTGSE---------------------LMDRMREQSTKFGTEIITETVSKVDLS 93 G +G G L + K G ++ +D Sbjct: 68 CGHAGEGALGIRVRAPEIDIAKSVAWKDGIVDRLTRGVGALLKKSGVRVLHGEARVID-- 125 Query: 94 SKPFKLWTEFNEDAEPVTTDAIILATGASA-KRMHLPGEETYWQKGISACAVCDGAVPIF 152 + A + + ++LATG+ + +P G + D P Sbjct: 126 --GKTVEVVSAGHAVRIGCEHLLLATGSEPVELPSMP-------FGGHVVSSTDALSPAT 176 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ-----KRAEKNEKIEI 207 K L V+G G E K G V ++ + + + + + + + Sbjct: 177 LPKRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERVLPAYDAELVRPVADSLARLGVRL 236 Query: 208 LYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT-KIVAGQVDTDEA 266 L G + E LP + A+G P + D Sbjct: 237 WLGHKVLGLDKHGAVRVQAA-----DGAEQTLPADRVLVAVGRRPRVDGFGLETLMLDRN 291 Query: 267 GYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 G + + TS+ +A GDV A + G M A Sbjct: 292 GRALRIDDTCRTSMRNVWAIGDVAGEPM-LAHRAMAQGEMVA 332 >1ONF-A nrPDB Length = 500 Score = 101 bits (252), Expect = 4e-22, Method: Composition-based stats. Identities = 39/193 (20%), Positives = 69/193 (35%), Gaps = 22/193 (11%) Query: 106 DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 + E + I++A G + KGI D I +K + ++G G Sbjct: 136 NEEILEGRNILIAVGNKPVFPPV--------KGIENTISSDEFFNIKESKKIGIVGSGYI 187 Query: 166 ACEEAQFLTKYGSKVFMLVRKD----HLRASTIMQ-KRAEKNEKIEILYNTVALEAKGDG 220 A E + + G ++ R + S I + K I I+ +E K Sbjct: 188 AVELINVIKRLGIDSYIFARGNRILRKFDESVINVLENDMKKNNINIVTFADVVEIKKVS 247 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTP---ATKIVAGQVDTDEAGYIKTVPGSSL 277 ++ + + + E + Y +G +P K+ V+T+ YI V + Sbjct: 248 DKNLSIHLSDGRIYEH----FDHVIYCVGRSPDTENLKLEKLNVETN-NNYI-VVDENQR 301 Query: 278 TSVPGFFAAGDVQ 290 TSV +A GD Sbjct: 302 TSVNNIYAVGDCC 314 >2HQM-A nrPDB Length = 479 Score = 100 bits (250), Expect = 6e-22, Method: Composition-based stats. Identities = 58/340 (17%), Positives = 110/340 (32%), Gaps = 51/340 (15%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEG------MMANGIAAGGQLTTTTEI--- 52 H +IG G +A A K +L E + G + +++ Sbjct: 10 KHYDYLVIGGGSGGVASARRAASYGAKTLLVEAKALGGTCVNVGCVPKKVMWYASDLATR 69 Query: 53 ----------ENFPGFPDGLT--GSELMDRMREQSTKFG----TEIITETVSKV----DL 92 +N P + LT E + + + E V V Sbjct: 70 VSHANEYGLYQNLPLDKEHLTFNWPEFKQKRDAYVHRLNGIYQKNLEKEKVDVVFGWARF 129 Query: 93 SSKPFKLWTEFNEDAEPVTTDAIILATGASAKRM-HLPGEETYWQKGISACAVCDGAVPI 151 + + + E + + I++ATG A ++PG E G + Sbjct: 130 NKDGNVEVQKRDNTTEVYSANHILVATGGKAIFPENIPGFEL----GTDSDGFFRLEE-- 183 Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRK-------DHLRASTIMQKRAEKNEK 204 + K + V+G G E A GS+ +++R D +TI ++ Sbjct: 184 -QPKKVVVVGAGYIGIELAGVFHGLGSETHLVIRGETVLRKFDECIQNTITDHYVKEGIN 242 Query: 205 IEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTD 264 + L V +E K + ++K + ++ V L + IG + + V Sbjct: 243 VHKLSKIVKVE-----KNVETDKLKIHMNDSKSIDDVDELIWTIGRKSHLGMGSENVGIK 297 Query: 265 EAGYIKTV-PGSSLTSVPGFFAAGDVQDS-KYRQAITSAG 302 + + + T+VP ++ GDV + +AG Sbjct: 298 LNSHDQIIADEYQNTNVPNIYSLGDVVGKVELTPVAIAAG 337 >1DXL-A nrPDB Length = 470 Score = 100 bits (250), Expect = 7e-22, Method: Composition-based stats. Identities = 46/202 (22%), Positives = 82/202 (40%), Gaps = 17/202 (8%) Query: 102 EFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISAC-AVCDGAVPIFRNKPLAVI 160 + V II+ATG+ K + PG +K +S+ A+ +P K L VI Sbjct: 130 TIEGENTVVKGKHIIIATGSDVKSL--PGVTIDEKKIVSSTGALALSEIP----KKLVVI 183 Query: 161 GGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ-----KRAEKNEKIEILYNTVALE 215 G G E + GS+V ++ + + + +R+ + + ++ T + Sbjct: 184 GAGYIGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIRKQFQRSLEKQGMKFKLKTKVVG 243 Query: 216 AKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYIKTV 272 G + L ++ + E+T + + + G TP T + V+TD+ G I V Sbjct: 244 VDTSGDGVK-LTVEPSAGGEQTIIEADVVLVSAGRTPFTSGLNLDKIGVETDKLGRIL-V 301 Query: 273 PGSSLTSVPGFFAAGDVQDSKY 294 T+V G +A GDV Sbjct: 302 NERFSTNVSGVYAIGDVIPGPM 323 Score = 35.0 bits (79), Expect = 0.047, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 38/126 (30%), Gaps = 22/126 (17%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 K+ +IG+G R + + E ++ Sbjct: 179 KLVVIGAGYIGLEMGSVWGRIGSEVTVVEFASEIVPTMDAEIR----------------- 221 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEP--VTTDAIILATGAS 122 + + +Q KF + V VD S KL E + E + D ++++ G + Sbjct: 222 KQFQRSLEKQGMKFKLKT---KVVGVDTSGDGVKLTVEPSAGGEQTIIEADVVLVSAGRT 278 Query: 123 AKRMHL 128 L Sbjct: 279 PFTSGL 284 >4DNA-A nrPDB Length = 463 Score = 99.7 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 49/194 (25%), Positives = 72/194 (37%), Gaps = 22/194 (11%) Query: 107 AEPVTTDAIILATGASA-KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 + VT + I++A G LPG E S A A+P + + + GGG Sbjct: 129 GKTVTAERIVIAVGGHPSPHDALPGHELCI---TSNEAFDLPALP----ESILIAGGGYI 181 Query: 166 ACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR-----AEKNEKIEILYNTVALEAKGDG 220 A E A G K ++ R + + R A + + I IL + D Sbjct: 182 AVEFANIFHGLGVKTTLIYRGKEILSRFDQDMRRGLHAAMEEKGIRILCEDIIQSVSADA 241 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKTVPGSSL 277 + ++ + A+G P T + A V T+E G I V S Sbjct: 242 DGRRVAT-----TMKHGEIVADQVMLALGRMPNTNGLGLEAAGVRTNELGAI-IVDAFSR 295 Query: 278 TSVPGFFAAGDVQD 291 TS PG +A GDV D Sbjct: 296 TSTPGIYALGDVTD 309 >5JCN-A nrPDB Length = 451 Score = 99.3 bits (246), Expect = 2e-21, Method: Composition-based stats. Identities = 50/224 (22%), Positives = 83/224 (37%), Gaps = 20/224 (8%) Query: 85 ETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAV 144 E + ++ T + T + +I+ATG+S ++ G + I Sbjct: 105 ELILSTEIVKADLASKTLTSAVGATFTYEILIIATGSSVIKLSDFGTQGADSNNILYLRE 164 Query: 145 CDGA------VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR 198 D A + + ++GGG E + L V M+ + Sbjct: 165 VDDADKLVAAIQAKKGGKAVIVGGGYIGLELSAALKINDFDVTMVFPEPWCMPRLFTADI 224 Query: 199 A------EKNEKIEILYNTVALEAKGD-GKLLNALRIKNTKKNEETDLPVSGLFYAIGHT 251 A N+ ++I+ TVA+ D + A+ +KN + L + +G Sbjct: 225 AAFYESYYTNKGVKIVKGTVAVGFDADANGDVTAVNLKNG-----SVLEADIVVVGVGGR 279 Query: 252 PATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYR 295 P T + GQV +E G IKT TSVPG +A GDV + Sbjct: 280 PLTTLFKGQV-AEEKGGIKT-DAFFETSVPGVYAVGDVATFPMK 321 >1FEC-A nrPDB Length = 490 Score = 98.9 bits (245), Expect = 3e-21, Method: Composition-based stats. Identities = 73/358 (20%), Positives = 117/358 (32%), Gaps = 77/358 (21%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIK-PILYEGMMANGIAAGGQLTTTTEIENFPGFPD--G 61 + +IG+G A A K + + +G L T N P Sbjct: 5 DLVVIGAGSGGLEAGWNAASLHKKRVAVIDLQKHHGPPHYAALGGTCV--NVGCVPKKLM 62 Query: 62 LTGSELMDRMREQSTKFGTEIITETV------------SKVDLSSKPFKLWTEFNEDA-- 107 +TG+ MD +RE + FG E+ E+V V + ++ E Sbjct: 63 VTGANYMDTIRESA-GFGWELDRESVRPNWKALIAAKNKAVSGINDSYEGMFADTEGLTF 121 Query: 108 --------------------------EPVTTDAIILATGASAKRMHLPGEETYWQKGISA 141 E + T+ I+LATG+ + + + G++ S Sbjct: 122 HQGFGALQDNHTVLVRESADPNSAVLETLDTEYILLATGSWPQHLGIEGDDLCI---TSN 178 Query: 142 CAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKY---GSKVFMLVRKD--------HLR 190 A P K +GGG + E A Y G +V + R D LR Sbjct: 179 EAFYLDEAP----KRALCVGGGYISIEFAGIFNAYKARGGQVDLAYRGDMILRGFDSELR 234 Query: 191 ASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGH 250 Q RA I + + + + + + E D V + AIG Sbjct: 235 KQLTEQLRAN---GINVRTHENPAKVTKNADGTRHVVFE---SGAEADYDV--VMLAIGR 286 Query: 251 TPATK---IVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGC 305 P ++ + V+ + G IK V S T+V +A GDV D + + G Sbjct: 287 VPRSQTLQLEKAGVEVAKNGAIK-VDAYSKTNVDNIYAIGDVTDRVMLTPV-AINEGA 342 >3LXD-A nrPDB Length = 415 Score = 98.1 bits (243), Expect = 4e-21, Method: Composition-based stats. Identities = 45/219 (20%), Positives = 77/219 (35%), Gaps = 26/219 (11%) Query: 86 TVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVC 145 V +D ++ KL D + +I ATG +R+ G + G+ A Sbjct: 87 EVVSLDPAAHTVKL-----GDGSAIEYGKLIWATGGDPRRLSCVGADLA---GVHAVRTK 138 Query: 146 DGAVPIFRN-----KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAE 200 + A + K VIGGG E A LTK+G V +L + A + +E Sbjct: 139 EDADRLMAELDAGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVAGEALSE 198 Query: 201 ------KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT 254 + +++ +GDG + +R+++ + +P + IG P Sbjct: 199 FYQAEHRAHGVDLRTGAAMDCIEGDGTKVTGVRMQDG-----SVIPADIVIVGIGIVPCV 253 Query: 255 KIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSK 293 + G V TS+ +A GD Sbjct: 254 GALISAGA--SGGNGVDVDEFCRTSLTDVYAIGDCAAHA 290 >3O0H-A nrPDB Length = 484 Score = 97.4 bits (241), Expect = 7e-21, Method: Composition-based stats. Identities = 41/195 (21%), Positives = 69/195 (35%), Gaps = 23/195 (11%) Query: 107 AEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR-NKPLAVIGGGDS 165 E ++ + I++ATGA KG C + + + K + ++GGG Sbjct: 150 GERISAEKILIATGAKI-------VSNSAIKGSDLCLTSNEIFDLEKLPKSIVIVGGGYI 202 Query: 166 ACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNE-----KIEILYNTVALEAKGDG 220 E A G K +L R D + + R N+ I I+Y + + Sbjct: 203 GVEFANIFHGLGVKTTLLHRGDLILRNFDYDLRQLLNDAMVAKGISIIYEATVSQVQSTE 262 Query: 221 KLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQVDTDEAGYIKTVPGSSL 277 N + + N + + + A G P T + V +E G + V Sbjct: 263 NCYN-VVLTNGQT-----ICADRVMLATGRVPNTTGLGLERAGVKVNEFGAV-VVDEKMT 315 Query: 278 TSVPGFFAAGDVQDS 292 T+V +A GDV Sbjct: 316 TNVSHIWAVGDVTGH 330 >3IC9-A nrPDB Length = 492 Score = 97.0 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 67/343 (19%), Positives = 113/343 (32%), Gaps = 39/343 (11%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEG------------MMANGIAAGGQLTT 48 +++ V IIG+G A A + K +L EG M + + A + Sbjct: 6 VINVDVAIIGTGTAGMGAYRAAKKHTDKVVLIEGGAYGTTCARVGCMPSKLLIAAADASY 65 Query: 49 TTEIENFPGF---PDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKL------ 99 + G + G +M R++ + +F + E+V D K Sbjct: 66 HASQTDLFGIQVDRISVNGKAVMKRIQTERDRF-VGFVVESVESFDEQDKIRGFAKFLDE 124 Query: 100 WTEFNEDAEPVTTDAIILATGASAKRMHL---PGEETYWQKGISACAVCDGAVPIFRNKP 156 T +D V I++ATG+ G + +P K Sbjct: 125 HTLQVDDHSQVIAKRIVIATGSRPNYPEFLAAAGSRLLTNDNLFEL----NDLP----KS 176 Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL--RASTIMQKRAEKNEKIEILYNTVAL 214 +AV G G E Q L++ G V + R + M++ AEK E ++ A Sbjct: 177 VAVFGPGVIGLELGQALSRLGVIVKVFGRSGSVANLQDEEMKRYAEKTFNEEFYFDAKAR 236 Query: 215 EAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA---TKIVAGQVDTDEAGYIKT 271 K I K ++T + A G + ++ D+ Sbjct: 237 VISTIEKEDAVEVIYFDKSGQKTTESFQYVLAATGRKANVDKLGLENTSIELDKKNSPLF 296 Query: 272 VPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKY 314 + TSV F AGD ++ +A G +A +A Y Sbjct: 297 DELTLQTSVDHIFVAGDANNT-LTLLHEAADDGKVAGTNAGAY 338 >2QAE-A nrPDB Length = 468 Score = 97.0 bits (240), Expect = 1e-20, Method: Composition-based stats. Identities = 47/217 (21%), Positives = 83/217 (38%), Gaps = 19/217 (8%) Query: 102 EFNEDAEPVTTDAIILATGASAKRMH-LPGEETYWQKGISACAVCDGAVPIFRNKPLAVI 160 + E + T I+ATG+ + LP +E A A+ K + VI Sbjct: 127 GLDGKQEMLETKKTIIATGSEPTELPFLPFDEKVVLSSTGALALPR------VPKTMVVI 180 Query: 161 GGGDSACEEAQFLTKYGSKVFMLVRKDHLRA------STIMQKRAEKNEKIEILYNTVAL 214 GGG E + G++V ++ + + KNEK++ + +T + Sbjct: 181 GGGVIGLELGSVWARLGAEVTVVEFAPRCAPTLDEDVTNALVGALAKNEKMKFMTSTKVV 240 Query: 215 EAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYIKT 271 +G + +L ++ K + + L ++G P T + V +E G++K Sbjct: 241 GGTNNGDSV-SLEVE-GKNGKRETVTCEALLVSVGRRPFTGGLGLDKINVAKNERGFVKI 298 Query: 272 VPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 TS+P +A GDV D A + G A Sbjct: 299 GD-HFETSIPDVYAIGDVVDKGPMLAHKAEDEGVACA 334 >2YAU-A nrPDB Length = 511 Score = 95.4 bits (236), Expect = 3e-20, Method: Composition-based stats. Identities = 52/209 (24%), Positives = 82/209 (39%), Gaps = 25/209 (11%) Query: 108 EPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSAC 167 E + T+ I++ATG+ R+ +PG+E S A P K + +GGG A Sbjct: 169 ETLDTEYILIATGSWPTRLGVPGDEFCI---TSNEAFYLEDAP----KRMLCVGGGYIAV 221 Query: 168 EEAQFLTKY---GSKVFMLVRKDH-LRA-STIMQKRAEKN---EKIEILYNTVALEAKGD 219 E A Y G V + R D LR T ++K K I + N + + Sbjct: 222 EFAGIFNGYKPCGGYVDLCYRGDLILRGFDTEVRKSLTKQLGANGIRVRTNLNPTKITKN 281 Query: 220 GKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---AGQVDTDEAGYIKTVPGSS 276 N + N+ T+ + AIG P ++ + V T + G ++ V S Sbjct: 282 EDGSNHVHF-----NDGTEEDYDQVMLAIGRVPRSQALQLDKAGVRTGKNGAVQ-VDAYS 335 Query: 277 LTSVPGFFAAGDVQDSKYRQAITSAGSGC 305 TSV +A GDV + + + G Sbjct: 336 KTSVDNIYAIGDVTNRVMLTPV-AINEGA 363 >4NEW-A nrPDB Length = 492 Score = 95.1 bits (235), Expect = 3e-20, Method: Composition-based stats. Identities = 71/359 (19%), Positives = 125/359 (34%), Gaps = 74/359 (20%) Query: 5 KVTIIGSGPAAHTAAIYLA-RAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD--G 61 + +IG+G AA A + + + + M +G L T N P Sbjct: 7 DLVVIGAGSGGLEAAWNAATLYKKRVAVIDVQMVHGPPFFSALGGTCV--NVGCVPKKLM 64 Query: 62 LTGSELMDRMREQSTKFGTE---------------IITETVSKVDLSSKPFKLWTEFNE- 105 +TG++ M+ +RE + FG E + E V ++ S TE E Sbjct: 65 VTGAQYMEHLRESA-GFGWEFDRTTLRAEWKNLIAVKDEAVLNINKSYDEMFRDTEGLEF 123 Query: 106 ------------------------DAEPVTTDAIILATGASAKRMHLPGEETYWQKGISA 141 E + T+ I+LA+G+ ++PG E Sbjct: 124 FLGWGSLESKNVVNVRESADPASAVKERLETEHILLASGSWPHMPNIPGIE-------HC 176 Query: 142 CAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK---VFMLVRKDHLR------AS 192 + + + + +GGG + E A Y K V + R + + Sbjct: 177 ISSNEAFYLPEPPRRVLTVGGGFISVEFAGIFNAYKPKDGQVTLCYRGEMILRGFDHTLR 236 Query: 193 TIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP 252 + K+ N I+IL + + + ++ ++ KK + + AIG +P Sbjct: 237 EELTKQLTAN-GIQILTKENPAKVELNADGSKSVTFESGKK-----MDFDLVMMAIGRSP 290 Query: 253 ATKIVA--GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAAL 309 TK + + G ++ V S T+V +A GDV + R +T AAL Sbjct: 291 RTKDLQLQNAGVMIKNGGVQ-VDEYSRTNVSNIYAIGDVTN---RVMLTPVAINEAAAL 345 >4B1B-A nrPDB Length = 542 Score = 95.1 bits (235), Expect = 4e-20, Method: Composition-based stats. Identities = 58/349 (16%), Positives = 118/349 (33%), Gaps = 59/349 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIA----AGGQLTTTTEIE----NFP 56 +IG GP +A A + +L++ + + GG + ++ Sbjct: 44 DYVVIGGGPGGMASAKEAAAHGARVLLFDYVKPSSQGTKWGIGGTCVNVGCVPKKLMHYA 103 Query: 57 GFPDGLTGSE-----------------LMDRMREQSTKFG-----------TEIITETVS 88 G + + L+ ++ + I Sbjct: 104 GHMGSIFKLDSKAYGWKFDNLKHDWKKLVTTVQSHIRSLNFSYMTGLRSSKVKYINGLAK 163 Query: 89 KVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMH-LPGEETYWQKGISACAVCDG 147 D ++ + L + +++ E VT I++ATG + G + I++ + Sbjct: 164 LKDKNTVSYYLKGDLSKE-ETVTGKYILIATGCRPHIPDDVEGAKEL---SITSDDIF-- 217 Query: 148 AVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAST----IMQKRAEKNE 203 ++ K L V+G A E + FL G V + VR LR + K + + Sbjct: 218 SLKKDPGKTL-VVGASYVALECSGFLNSLGYDVTVAVRSIVLRGFDQQCAVKVKLYMEEQ 276 Query: 204 KIEILYNTVALEA-KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA---TKIVAG 259 + + + K D K+L K ++ + YAIG + + Sbjct: 277 GVMFKNGILPKKLTKMDDKILVEFSDKTSEL-------YDTVLYAIGRKGDIDGLNLESL 329 Query: 260 QVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 ++ +++ S T++P FA GDV ++ A + +G + A Sbjct: 330 NMNVNKSNNKIIADHLSCTNIPSIFAVGDVAENVPELAPVAIKAGEILA 378 >3FG2-P nrPDB Length = 404 Score = 92.0 bits (227), Expect = 3e-19, Method: Composition-based stats. Identities = 55/292 (18%), Positives = 97/292 (33%), Gaps = 25/292 (8%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I G+G A A+ L +A+ + + Q ++ G + Sbjct: 4 VLIAGAGHAGFQVAVSLRQAKYPGRIALINDEKHLPY--QRPPLSKAY----LKSGGDPN 57 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKR 125 LM R + E+I++ + +D + L + ++LATGA + Sbjct: 58 SLMFRPEKFFQDQAIELISDRMVSIDREGRKLLL-----ASGTAIEYGHLVLATGARNRM 112 Query: 126 MHLPGEETYWQKGISACAVCDGAVPIFRNKP-LAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + +P + + +K + VIG G E A G +V ++ Sbjct: 113 LDVPNASLPDVLYLRTLDESEVLRQRMPDKKHVVVIGAGFIGLEFAATARAKGLEVDVVE 172 Query: 185 RKDHLRASTIMQKRA------EKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETD 238 + A + + + I + Y A E +G + + + + Sbjct: 173 LAPRVMARVVTPEISSYFHDRHSGAGIRMHYGVRATEIAAEGDRVTGVVLSDGNT----- 227 Query: 239 LPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQ 290 LP + +G P +I A AG I V LTS P A GD Sbjct: 228 LPCDLVVVGVGVIPNVEIAAAAGLPTAAGII--VDQQLLTSDPHISAIGDCA 277 >2VDC-G nrPDB Length = 456 Score = 90.4 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 44/236 (18%), Positives = 84/236 (35%), Gaps = 38/236 (16%) Query: 114 AIILATGA-SAKRMHLPGE--------------ETYWQKGISACAVCDGAVPIFRNKPLA 158 A+++ATG A+ + PG G + A +G++ K + Sbjct: 210 AVLVATGVYKARDIKAPGSGLGNIVAALDYLTTSNKVSLGDTVEAYENGSLNA-AGKHVV 268 Query: 159 VIGGGDSACEEAQFLTKYG-SKVFMLVRKDHLRASTIMQKRAE-KNEKIEILYNTVALEA 216 V+GGGD+A + + + G + V L R+D ++ A + E +E ++ Sbjct: 269 VLGGGDTAMDCVRTAIRQGATSVKCLYRRDRKNMPGSQREVAHAEEEGVEFIWQAAPEGF 328 Query: 217 KGDGKLLNALR---------------IKNTKKNEETDLPVSGLFYAIGHTPA---TKIVA 258 GD ++ +R + E + + A+G P Sbjct: 329 TGD-TVVTGVRAVRIHLGVADATGRQTPQVIEGSEFTVQADLVIKALGFEPEDLPNAFDE 387 Query: 259 GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKY 314 ++ G + + +T++ G FAAGD+ + + G AA Y Sbjct: 388 PELKVTRWGTLLVDHRTKMTNMDGVFAAGDIVRGA-SLVVWAIRDGRDAAEGIHAY 442 >1Q1R-A nrPDB Length = 431 Score = 90.4 bits (223), Expect = 9e-19, Method: Composition-based stats. Identities = 37/205 (18%), Positives = 64/205 (31%), Gaps = 19/205 (9%) Query: 101 TEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR----NKP 156 D + D ++LATG + + + + A I R + Sbjct: 92 QVILSDGRALDYDRLVLATGGRPRPLPVASGAVGKANNFRYLRTLEDAECIRRQLIADNR 151 Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAS------TIMQKRAEKNEKIEILYN 210 L VIGGG E A K V +L + + + + ++I Sbjct: 152 LVVIGGGYIGLEVAATAIKANMHVTLLDTAARVLERVTAPPVSAFYEHLHREAGVDIRTG 211 Query: 211 TVA--LEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGY 268 T E D + + A+ ++ + LP + IG P ++ + + G Sbjct: 212 TQVCGFEMSTDQQKVTAVLCEDGTR-----LPADLVIAGIGLIPNCELASAAGLQVDNG- 265 Query: 269 IKTVPGSSLTSVPGFFAAGDVQDSK 293 + TS P A GD Sbjct: 266 -IVINEHMQTSDPLIMAVGDCARFH 289 Score = 36.1 bits (82), Expect = 0.020, Method: Composition-based stats. Identities = 23/123 (18%), Positives = 39/123 (31%), Gaps = 23/123 (18%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 N++ +IG G A +A + L + T +E P Sbjct: 150 NRLVVIGGGYIGLEVAATAIKANMHVTLLD-------------TAARVLERVTAPP---- 192 Query: 64 GSELMDRMREQS-TKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 + E + G +I T T V ++S+ K+ ED + D +I G Sbjct: 193 ----VSAFYEHLHREAGVDIRTGTQVCGFEMSTDQQKVTAVLCEDGTRLPADLVIAGIGL 248 Query: 122 SAK 124 Sbjct: 249 IPN 251 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 21/127 (16%), Positives = 34/127 (26%), Gaps = 28/127 (22%) Query: 154 NKPLAVIGGGDSACEEAQFLTK---------YGSKVFMLVRKDHLRASTIMQKR------ 198 N + ++G G + E A L G + L + + K Sbjct: 4 NDNVVIVGTGLAGVEVAFGLRASGWEGNIRLVGDATVIPHHLPPLSKAYLAGKATAESLY 63 Query: 199 -----AEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA 253 A + I++L T D + ++ L L A G P Sbjct: 64 LRTPDAYAAQNIQLLGGTQVTAINRDR--------QQVILSDGRALDYDRLVLATGGRPR 115 Query: 254 TKIVAGQ 260 VA Sbjct: 116 PLPVASG 122 >3II4-A nrPDB Length = 466 Score = 90.0 bits (222), Expect = 1e-18, Method: Composition-based stats. Identities = 70/350 (20%), Positives = 114/350 (32%), Gaps = 64/350 (18%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 M H V ++G+GP + AAI A+ + + E G+ N P Sbjct: 3 MTHYDVVVLGAGPGGYVAAIRAAQLGLSTAIVEPKYWGGVCL-----------NVGCIPS 51 Query: 61 --GLTGSELMDRMREQSTKFGT----------------EIITETVSKVDLSSKPFKLWTE 102 L +EL+ + + FG ++ V+ V K K+ Sbjct: 52 KALLRNAELVHIFTKDAKAFGISGEVTFDYGIAYDRSRKVAEGRVAGVHFLMKKNKITEI 111 Query: 103 FN----------------EDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCD 146 E VT D I+ATG+S + +PG + Sbjct: 112 HGYGTFADANTLLVDLNDGGTESVTFDNAIIATGSSTRL--VPGTSLSANVVTYEEQILS 169 Query: 147 GAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ-----KRAEK 201 +P K + + G G E L YG V ++ + ++ K Sbjct: 170 RELP----KSIIIAGAGAIGMEFGYVLKNYGVDVTIVEFLPRALPNEDADVSKEIEKQFK 225 Query: 202 NEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK---IVA 258 + IL T E+ DG + + + TK +L + AIG P + + Sbjct: 226 KLGVTILTATKV-ESIADGG--SQVTVTVTKDGVAQELKAEKVLQAIGFAPNVEGYGLDK 282 Query: 259 GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 V + I V T+V +A GDV + A + G +AA Sbjct: 283 AGVALTDRKAIG-VDDYMRTNVGHIYAIGDVN-GLLQLAHVAEAQGVVAA 330 >3NTA-A nrPDB Length = 574 Score = 89.3 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 43/238 (18%), Positives = 82/238 (34%), Gaps = 24/238 (10%) Query: 77 KFGTEI-ITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYW 135 +F E+ + V +D ++K + + + D ++L+ GA+ +PG + Sbjct: 70 RFNVEVRVKHEVVAIDRAAKLVTVRRLLDGSEYQESYDTLLLSPGAAPIVPPIPGVDNPL 129 Query: 136 QKGISACAVCDGAVPIFRNKPL---AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAS 192 + D + + + V+GGG E + L G K +L D + Sbjct: 130 THSLRNIPDMDRILQTIQMNNVEHATVVGGGFIGLEMMESLHHLGIKTTLLELADQVMTP 189 Query: 193 TIMQKRAEKN-----EKIEILYNTVALEAK------------GDGKLLNALRIKNTKKNE 235 + + + +++ T E G+ ++ + Sbjct: 190 VDREMAGFAHQAIRDQGVDLRLGTALSEVSYQVQTHVASDAAGEDTAHQHIKGHLSLTLS 249 Query: 236 ETD-LPVSGLFYAIGHTPATKIVAG-QVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQD 291 + L L AIG P T++ + E G IK V TS P +A GD + Sbjct: 250 NGELLETDLLIMAIGVRPETQLARDAGLAIGELGGIK-VNAMMQTSDPAIYAVGDAVE 306 >2CVJ-A nrPDB Length = 180 Score = 89.3 bits (220), Expect = 2e-18, Method: Composition-based stats. Identities = 40/169 (23%), Positives = 72/169 (42%), Gaps = 18/169 (10%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V ++G GP+ +AA++LARA +K ++ +G + ++ + + N+PG D +G Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLDGGRS-------KVKGVSRVPNYPGLLDEPSG 55 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 EL+ R+ + ++G E+ V V F++ TE + + ++L T Sbjct: 56 EELLRRLEAHARRYGAEVRPGVVKGVRDMGGVFEVETEEGVE----KAERLLLCTHKDPT 111 Query: 125 RMHL-----PGEETYWQKGISACAVCDGAVPIFRNKPL--AVIGGGDSA 166 L G +G A + R K A+I GD A Sbjct: 112 LPSLLGLTRRGAYIDTDEGGRTSYPRVYAAGVARGKVPGHAIISAGDGA 160 Score = 52.7 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 35/168 (20%), Positives = 53/168 (31%), Gaps = 22/168 (13%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKI---------- 205 + V+GGG S A FL + G KV +L D R+ R + Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVL---DGGRSKVKGVSRVPNYPGLLDEPSGEELL 59 Query: 206 -EILYNTVALEAKGDGKLLNALR----IKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQ 260 + + A+ ++ +R + + E + L P + G Sbjct: 60 RRLEAHARRYGAEVRPGVVKGVRDMGGVFEVETEEGVE-KAERLLLCTHKDPTLPSLLG- 117 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 G TS P +AAG + AI SAG G A Sbjct: 118 --LTRRGAYIDTDEGGRTSYPRVYAAGVARGKVPGHAIISAGDGAYVA 163 >1LVL-A nrPDB Length = 458 Score = 88.1 bits (217), Expect = 5e-18, Method: Composition-based stats. Identities = 44/240 (18%), Positives = 85/240 (35%), Gaps = 27/240 (11%) Query: 75 STKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETY 134 K G +++ +D K ++ D + + + ++LATG+S+ + + Sbjct: 106 LKKHGVKVVHGWAKVLD--GKQVEV------DGQRIQCEHLLLATGSSSVELPM------ 151 Query: 135 WQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTI 194 G + + P + L V+GGG E K G++V ++ ++ + + Sbjct: 152 LPLGGPVISSTEALAPKALPQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERILPTYD 211 Query: 195 MQ-----KRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIG 249 + + K I + + N + N K + L + A+G Sbjct: 212 SELTAPVAESLKKLGIALHLGHSVEGYE------NGCLLANDGKGGQLRLEADRVLVAVG 265 Query: 250 HTPATKIVAGQ-VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 P TK + +D G + TS+ +A GDV A + G M A Sbjct: 266 RRPRTKGFNLECLDLKMNGAAIAIDERCQTSMHNVWAIGDVAGEPM-LAHRAMAQGEMVA 324 >2YVG-A nrPDB Length = 408 Score = 84.3 bits (207), Expect = 7e-17, Method: Composition-based stats. Identities = 43/301 (14%), Positives = 91/301 (30%), Gaps = 41/301 (13%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 + V ++G+G A+ + L +A + ++ + P Sbjct: 6 LKAPVVVLGAGLASVSFVAELRQAGYQGLITVVGDEAERP-----------YDRPPLSKD 54 Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 +++R + E + V S + T D + ++LATGA Sbjct: 55 FMAHGDAEKIRLDCKRAP---EVEWLLGVTAQSFDPQAHTVALSDGRTLPYGTLVLATGA 111 Query: 122 SAKRMH-LPGEETYWQKGISACAVCDGAVPIFRN----KPLAVIGGGDSACEEAQFLTKY 176 + + + L G + + A I L ++GGG E A Sbjct: 112 APRALPTLQGA----TMPVHTLRTLEDARRIQAGLRPQSRLLIVGGGVIGLELAATARTA 167 Query: 177 GSKVFMLVRKDHLRASTI------MQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKN 230 G V ++ + L + R + +++ + ++ + + + Sbjct: 168 GVHVSLVETQPRLMSRAAPATLADFVARYHAAQGVDLRFERSVT------GSVDGVVLLD 221 Query: 231 TKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQ 290 + T + + IG + + G V T+ P +A GDV Sbjct: 222 ----DGTRIAADMVVVGIGVLANDALARAAGLACDDG--IFVDAYGRTTCPDVYALGDVT 275 Query: 291 D 291 Sbjct: 276 R 276 >1V59-A nrPDB Length = 478 Score = 82.3 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 67/338 (19%), Positives = 121/338 (35%), Gaps = 55/338 (16%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKP----------------------------ILYE 33 + V IIG GPA + AAI A+ L+ Sbjct: 4 KSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGGTCLNVGCIPSKALLNNSHLFH 63 Query: 34 GMMANGIAAGGQLTTTTEIENFPGF--------PDGLTGSELMDRMREQSTKFGTEIITE 85 M G + +I N F G EL+ + + + T + E Sbjct: 64 QMHTEAQKRGIDVNGDIKI-NVANFQKAKDDAVKQLTGGIELLFK-KNKVTYYKGNGSFE 121 Query: 86 TVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVC 145 +K+ ++ P ++ + II+ATG+ + PG E +K +S+ Sbjct: 122 DETKIRVT--PVDGLEGTVKEDHILDVKNIIVATGS--EVTPFPGIEIDEEKIVSSTGAL 177 Query: 146 DGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQ-----KRAE 200 K L +IGGG E ++ GSKV ++ + + AS + ++ Sbjct: 178 SLKE---IPKRLTIIGGGIIGLEMGSVYSRLGSKVTVVEFQPQIGASMDGEVAKATQKFL 234 Query: 201 KNEKIEILYNTVALEAK-GDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP---ATKI 256 K + ++ +T + AK D K + + +++TK N++ +L L A+G P Sbjct: 235 KKQGLDFKLSTKVISAKRNDDKNVVEIVVEDTKTNKQENLEAEVLLVAVGRRPYIAGLGA 294 Query: 257 VAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKY 294 ++ D+ G + + + P GDV Sbjct: 295 EKIGLEVDKRGRL-VIDDQFNSKFPHIKVVGDVTFGPM 331 >3L8K-A nrPDB Length = 466 Score = 82.3 bits (202), Expect = 3e-16, Method: Composition-based stats. Identities = 56/348 (16%), Positives = 118/348 (33%), Gaps = 42/348 (12%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG-----------------IAAGG 44 + V +IG+G A + A LA+A+ ++ + G I Sbjct: 3 LKYDVVVIGAGGAGYHGAFRLAKAKYNVLMADPKGELGGNCLYSGCVPSKTVREVIQTAW 62 Query: 45 QLTTTTEIENFPGFPDGLTGSELMDRMR-----EQSTKFGTEIITETVSKVDLSSKPFKL 99 +LT ++ F + + +R +++ T + K+ + Sbjct: 63 RLTNIANVKIPLDFSTVQDRKDYVQELRFKQHKRNMSQYETLTFYKGYVKIKDPTHVI-- 120 Query: 100 WTEFNEDAEPVTTDA--IILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR-NKP 156 ++ + + + +I+A+GA ++ LPG E +++ + + + Sbjct: 121 --VKTDEGKEIEAETRYMIIASGAETAKLRLPGVE----YCLTSDDIFGYKTSFRKLPQD 174 Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH---LRASTIMQKRAEKNEKIEILYNTVA 213 + +IG G E A G + ++ D + K+ I +N+ Sbjct: 175 MVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLEDQDIVNTLLSILKLNIKFNSPV 234 Query: 214 LEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVP 273 E K + +TK + + + + A G P A ++ + V Sbjct: 235 TEVKKIKDDEYEVIY-STKDGSKKSIFTNSVVLAAGRRPVIPEGAREIGLSISKTGIVVD 293 Query: 274 GSSLTSVPGFFAAGDVQD-SKYRQAI----TSAGSGCMAALDAEKYLT 316 + T++P FA GD + Y A +A + MA Y+ Sbjct: 294 ETMKTNIPNVFATGDANGLAPYYHAAVRMSIAAANNIMANGMPVDYVD 341 >1XDI-A nrPDB Length = 499 Score = 81.6 bits (200), Expect = 4e-16, Method: Composition-based stats. Identities = 61/347 (17%), Positives = 118/347 (34%), Gaps = 57/347 (16%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFP---GFP- 59 ++ I+G GPA + AA+ A + + + +GI L + F G Sbjct: 3 TRIVILGGGPAGYEAALVAATSHPETTQVTVIDCDGIGGAAVLDDCVPSKTFIASTGLRT 62 Query: 60 DGLTGSEL---------------------------MDRMREQSTKFGTEIITETVSKVDL 92 + L + Q G ++I +D Sbjct: 63 ELRRAPHLGFHIDFDDAKISLPQIHARVKTLAAAQSADITAQLLSMGVQVIAGRGELIDS 122 Query: 93 S---SKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCD-GA 148 + ++ T + D +++ATGAS + + P + ++ ++ + D A Sbjct: 123 TPGLARHRIKATAADGSTSEHEADVVLVATGASPRIL--PSAQPDGERILTWRQLYDLDA 180 Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA-----STIMQKRAEKNE 203 +P L V+G G + E T+ G V ++ +DH+ + ++ + + Sbjct: 181 LP----DHLIVVGSGVTGAEFVDAYTELGVPVTVVASQDHVLPYEDADAALVLEESFAER 236 Query: 204 KIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT---KIVAGQ 260 + + N A G + + + + + E + IG P T + Sbjct: 237 GVRLFKNARAASVTRTGAGV-LVTMTDGRTVEGSH-----ALMTIGSVPNTSGLGLERVG 290 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMA 307 + Y+ TV S T G +AAGD A +A G +A Sbjct: 291 IQLGRGNYL-TVDRVSRTLATGIYAAGDC-TGLLPLASVAAMQGRIA 335 >5NMX-A nrPDB Length = 425 Score = 80.8 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 55/302 (18%), Positives = 97/302 (32%), Gaps = 65/302 (21%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIE----------- 53 +V ++G+GP+ TAA YL +A + +++E GG T E Sbjct: 3 RVAVLGAGPSGLTAARYLKQAGFEVMVFERYHHV----GGTWNYTDETWMSEDGRPVYSS 58 Query: 54 -------NFP----GFPDG---------LTGSELMDRMREQSTKFGTEIIT---ETVSKV 90 N P FPD + E++ + F + V V Sbjct: 59 MYQNLFVNLPKELMAFPDFPFHDIEGSYVPSKEVLKYFDNFTDAFDLRKLIKLQHHVENV 118 Query: 91 DL--SSKPFKLWTEFNEDAEPVTTDAIILATGAS--AKRMHLPGEETYWQKGISACAVCD 146 S + DA+++ TG + + G + + A Sbjct: 119 RPCESGWLVTVTDLTTMVEHSFEFDAVVVCTGQTWCPLYPDVEGRSFFRGRLTHAHEF-- 176 Query: 147 GAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIE 206 + FRNK + ++G G S + A ++ +VF+ + L+ +E Sbjct: 177 RSPEPFRNKRVLIVGAGPSGHDMALHISYVSKEVFL--SRKELKP-------------VE 221 Query: 207 ILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV--AGQVDTD 264 L+ E LL +L ++ T V + Y G+ + V D Sbjct: 222 GLFPDNVTEK----PLLTSLSEYTAHFSDGTSTDVDEILYCTGYRYRFPFLSPECGVTVD 277 Query: 265 EA 266 E Sbjct: 278 EK 279 Score = 35.7 bits (81), Expect = 0.028, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 18/31 (58%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVR 185 + +AV+G G S A++L + G +V + R Sbjct: 2 RRVAVLGAGPSGLTAARYLKQAGFEVMVFER 32 >4FX9-A nrPDB Length = 453 Score = 80.8 bits (198), Expect = 7e-16, Method: Composition-based stats. Identities = 63/321 (19%), Positives = 121/321 (37%), Gaps = 52/321 (16%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARA--EIKPILYEGMMANGIAAGGQLTTTTEIENFPGFP 59 + KV IIG G A +AA + R E ++E A G P Sbjct: 5 MKKKVVIIGGGAAGMSAASRVKRLKPEWDVKVFEATEWVSHAPC-------------GIP 51 Query: 60 DGLTGSELMDRMREQ-----STKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDA 114 + G D++ K G ++ +++ + ++ E + D Sbjct: 52 YVVEGLSTPDKLMYYPPEVFIKKRGIDLHLN-AEVIEVDTGYVRVRENGGE--KSYEWDY 108 Query: 115 IILATGASAKRMHLPGEETYWQKGISACAVCDGAVPI------FRNKPLAVIGGGDSACE 168 ++ A GAS + + G KG+ + A+ I ++ + + +IGGG E Sbjct: 109 LVFANGASPQVPAIEGVNL---KGVFTADLPPDALAIREYMEKYKVENVVIIGGGYIGIE 165 Query: 169 EAQFLTKYGSKVFMLVRKDHLR-------ASTIMQKRAEKNEKIEILYNTVALEAKGDGK 221 A+ G V M+VR + + + I++++ +K+ + + + ++ +G+ + Sbjct: 166 MAEAFAAQGKNVTMIVRGERVLRRSFDKEVTDILEEKLKKH--VNLRLQEITMKIEGEER 223 Query: 222 LLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG-QVDTDEAGYIKTVPGSSLTSV 280 + + + + + A G P ++ V E G I T TSV Sbjct: 224 VEKVVT-------DAGEYKAELVILATGIKPNIELAKQLGVRIGETGAIWT-NEKMQTSV 275 Query: 281 PGFFAAGDVQDSKYRQAITSA 301 +AAGDV ++ R IT Sbjct: 276 ENVYAAGDVAET--RHVITGR 294 >2V3B-A nrPDB Length = 384 Score = 80.4 bits (197), Expect = 9e-16, Method: Composition-based stats. Identities = 54/298 (18%), Positives = 100/298 (33%), Gaps = 30/298 (10%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 + IIG+G A + A + + + L +G + + +T GF Sbjct: 4 RAPLVIIGTGLAGYNLAREWRKLDGETPLLMITADDGRSYSKPMLST-------GFSKNK 56 Query: 63 TGSELMDRMR-EQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 L + + I+T T V+ +D + + E V ++LA G Sbjct: 57 DADGLAMAEPGAMAEQLNARILTHTRVTGIDPGHQRIWI------GEEEVRYRDLVLAWG 110 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKP-LAVIGGGDSACEEAQFLTKYGSK 179 A R+ + G+ I+ K + ++G G CE A L+ G + Sbjct: 111 AEPIRVPVEGDAQDALYPINDLEDYARFRQAAAGKRRVLLLGAGLIGCEFANDLSSGGYQ 170 Query: 180 VFMLVRKDHLR------ASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKK 233 + ++ + + A+ + + + V K G+ L A + Sbjct: 171 LDVVAPCEQVMPGLLHPAAAKAVQAGLEGLGVRFHLGPVLASLKKAGEGLEA----HLSD 226 Query: 234 NEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQD 291 E +P + A+G P T++ G V S TS +A GD + Sbjct: 227 GEV--IPCDLVVSAVGLRPRTELAFAAGLAVNRG--IVVDRSLRTSHANIYALGDCAE 280 >4USR-A nrPDB Length = 361 Score = 79.6 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 50/312 (16%), Positives = 99/312 (31%), Gaps = 53/312 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE------------I 52 V +IG G AA T A +L R + +L + GG + I Sbjct: 9 DVIVIGGGQAALTTAYFLRRTSLSYLLLD----EQPGPGGAWLHAWDSLRLFSPAAWSSI 64 Query: 53 ENFPGFPDGLTG-----SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDA 107 +P P ++++D +R ++ I + +VD ++ LW D Sbjct: 65 AGWP-MPSPTEPGNPTRNDVIDYLRRYEDRYQFPI--QRPVRVDTVTRLDDLWRVQAGDQ 121 Query: 108 EPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS 165 + + A+I ATG + G E + I + F K + V+GGG+S Sbjct: 122 QWL-ARAVISATGTWSKPFIPPYEGRELFQGAQIHSAHY--RTPAPFAGKRVMVVGGGNS 178 Query: 166 ACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKI-------------------E 206 + L+ +++ + + + + Sbjct: 179 GAQVLAELSSVSETLWITQEPPAFLPDEVDGRVLFERATARWKAQQEGRSIDEPAGGFGD 238 Query: 207 ILYNTVALEAKGDGKLLNALRI-KNTKKN----EETDLPVSGLFYAIGHTPATKIVAGQV 261 I+ EA+ G L+ + T+ + + + + G PA + Sbjct: 239 IVMVPPVREARERGVLVAERPFARFTETGVEWADGRRENLDAVIWCSGFRPALDHLRELG 298 Query: 262 DTDEAGYIKTVP 273 + G ++ Sbjct: 299 VVEADGKVQVED 310 >1XHC-A nrPDB Length = 367 Score = 79.6 bits (195), Expect = 2e-15, Method: Composition-based stats. Identities = 62/326 (19%), Positives = 104/326 (31%), Gaps = 52/326 (15%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 +KV I+G+GP LA+ + + + + + I F P Sbjct: 9 SKVVIVGNGPGG----FELAKQLSQTYEVTVIDKEPVPYYSKPMLSHYIAGF--IPRNRL 62 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +D R++ G EI +K+ + + + V D ++LATGA A Sbjct: 63 FPYSLDWYRKR----GIEIRLAEEAKLIDRGRKVVIT-----EKGEVPYDTLVLATGARA 113 Query: 124 KRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGG-------DSACEEAQFLTKY 176 + + G+E R K G E A L + Sbjct: 114 REPQIKGKE--------YLLTLRTIFDADRIKESIENSGEAIIIGGGFIGLELAGNLAEA 165 Query: 177 GSKVFMLVRKDHLRASTI----MQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTK 232 G V ++ R M K + ++ N+ LEA +G L N+ I+ Sbjct: 166 GYHVKLIHRGAMFLGLDEELSNMIKDMLEETGVKFFLNSELLEANEEGVLTNSGFIEGKV 225 Query: 233 KNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDS 292 K AIG P + G + + TS +A GD + Sbjct: 226 K-----------ICAIGIVPNVDLARRSGI--HTGRGILIDDNFRTSAKDVYAIGDCAEY 272 Query: 293 KYRQAITSAGSGCMAALDAEKYLTSL 318 A T+ AA++ + L + Sbjct: 273 SGIIAGTA-----KAAMEQARVLADI 293 >4C5O-A nrPDB Length = 357 Score = 74.6 bits (182), Expect = 6e-14, Method: Composition-based stats. Identities = 61/361 (16%), Positives = 112/361 (31%), Gaps = 58/361 (16%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQ---------LTTTTE 51 M V +IG G + +A +L R+ + ++ + + GG L + Sbjct: 1 MDSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDA----EASPGGAWQHAWHSLHLFSPAG 56 Query: 52 IENFPGFP-DGLTGS-----ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNE 105 + PG+P G E++ + + K+ ++ +V S + Sbjct: 57 WSSIPGWPMPASQGPYPARAEVLAYLAQYEQKYALPVLRPI--RVQRVSHFGERLRVVAR 114 Query: 106 DAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGG 163 D A+I ATG A G E++ + + A F +A+IGGG Sbjct: 115 DGRQWLARAVISATGTWGEAYTPEYQGLESFAGIQLHSAHYSTPAP--FAGMRVAIIGGG 172 Query: 164 DSACEEAQFLTKYGS--KVFMLVRKDH-LRASTIMQKRAEK---------NEKIE----- 206 +S AQ L + + + + R + A + + + E E Sbjct: 173 NSG---AQILAEVSTVAETTWITRTEPAFLADDVDGRVLFERATERWKAQQEGREPDLPP 229 Query: 207 -----ILYNTVALEAKGDGKLLNA-----LRIKNTKKNEETDLPVSGLFYAIGHTPATKI 256 I+ L+A+ G L + + T+ + + G PA Sbjct: 230 GGFGDIVMVPPVLDARARGVLAAVPPPARFSPTGMQWADGTERAFDAVIWCTGFRPALSH 289 Query: 257 VAGQVDTDEAGYIKTVPGSSLT-SVPGFFAA--GDVQDSKYRQAITSAGSGCMAALDAEK 313 + G G ++ +VP + GD I A Sbjct: 290 LKGLDLVTPQGQVEVDGSGLRALAVPSVWLLGYGDWNGMASATLIGVTRYAREAVRQVTA 349 Query: 314 Y 314 Y Sbjct: 350 Y 350 >3KLJ-A nrPDB Length = 385 Score = 69.2 bits (168), Expect = 2e-12, Method: Composition-based stats. Identities = 64/325 (19%), Positives = 120/325 (36%), Gaps = 56/325 (17%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG 61 K+ I+G+GPA +AA K L + I + L N Sbjct: 8 KSTKILILGAGPAGFSAA--------KAALGKCDDITMINSEKYLPYYRPRLNEI-IAKN 58 Query: 62 LTGSELMDRMREQSTKFGTEIIT-ETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 + +++ + + K ++IT E + +D ++K L + E + + +I+A+G Sbjct: 59 KSIDDILIKKNDWYEKNNIKVITSEFATSIDPNNKLVTL-----KSGEKIKYEKLIIASG 113 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIF---RNK-PLAVIGGGDSACEEAQFLTKY 176 + A ++ +P + I + D A+ I +NK +IGGG E AQ + Sbjct: 114 SIANKIKVPHADE-----IFSLYSYDDALKIKDECKNKGKAFIIGGGILGIELAQAIIDS 168 Query: 177 GSKVFM-------LVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIK 229 G+ + L R+ ++ + ++ I+I N+ E GD Sbjct: 169 GTPASIGIILEYPLERQLDRDGGLFLKDKLDRL-GIKIYTNSNFEEM-GD---------- 216 Query: 230 NTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFFAAGDV 289 + S + A+G P + + G V TS+ +A GDV Sbjct: 217 --------LIRSSCVITAVGVKPNLDFIKDTEIASKRG--ILVNDHMETSIKDIYACGDV 266 Query: 290 QDSKYR---QAITSAGSGCMAALDA 311 + + + G +A L+A Sbjct: 267 AEFYGKNPGLINIANKQGEVAGLNA 291 >3UP5-A nrPDB Length = 545 Score = 65.8 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 32/208 (15%), Positives = 68/208 (32%), Gaps = 29/208 (13%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIA------AGGQLTTTTEIENFPGF 58 +IG+G A + +A +K + E G G +L T + + Sbjct: 11 DAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGTWYWNRYPGCRLDTESYAYGYFAL 70 Query: 59 PDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPF--------------KLWTEFN 104 + E + Q + +D+ +LW Sbjct: 71 KGIIPEWEWSENFASQPEML--RYVNRAADAMDVRKHYRFNTRVTAARYVENDRLWEVTL 128 Query: 105 EDAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPI-----FRNKPL 157 ++ E VT +I ATG ++++ + G +++ + + A F K + Sbjct: 129 DNEEVVTCRFLISATGPLSASRMPDIKGIDSFKGESFHSSRWPTDAEGAPKGVDFTGKRV 188 Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVR 185 VIG G + + + ++++ R Sbjct: 189 GVIGTGATGVQIIPIAAETAKELYVFQR 216 >1OJT-A nrPDB Length = 482 Score = 63.8 bits (154), Expect = 1e-10, Method: Composition-based stats. Identities = 47/230 (20%), Positives = 82/230 (35%), Gaps = 22/230 (9%) Query: 89 KVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGA 148 +V L++ + + V I+A G+ ++ E+ A A Sbjct: 126 EVSLTAGDAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALA----- 180 Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLR--ASTIMQKRAEKN---- 202 + K L + GG E + GS++ ++ D L A + K +K Sbjct: 181 LKEVPGKLLIIG-GGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYR 239 Query: 203 -EKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---A 258 + I + TVA+E K DG + + + A G P K++ Sbjct: 240 FDNIMVNTKTVAVEPKEDGVYVTF----EGANAPKEPQRYDAVLVAAGRAPNGKLISAEK 295 Query: 259 GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 V + G+I+ V T+VP +A GD+ A + G +AA Sbjct: 296 AGVAVTDRGFIE-VDKQMRTNVPHIYAIGDIVGQPM-LAHKAVHEGHVAA 343 Score = 28.4 bits (62), Expect = 4.0, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 66 ELMDRMREQST-KFGTEIITETVSKVD-LSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +L+ ++Q+ +F ++ V+ + + N EP DA+++A G + Sbjct: 227 DLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAP 286 Query: 124 K 124 Sbjct: 287 N 287 >1PS9-A nrPDB Length = 671 Score = 62.3 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 36/178 (20%), Positives = 62/178 (34%), Gaps = 30/178 (16%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 + ++G+GPA AI A + L++ GGQ +I PG + Sbjct: 373 KKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEI----GGQFNIAKQI---PGKEEFY 425 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS 122 RM ++++ KL D + D ILA+G Sbjct: 426 ETLRYYRRM------------------IEVTGVTLKLNHTVTAD-QLQAFDETILASGIV 466 Query: 123 AKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 + + G + K +S V P+ +A+IG G + A +L++ G Sbjct: 467 PRTPPIDGID--HPKVLSYLDVLRDKAPV--GNKVAIIGCGGIGFDTAMYLSQPGEST 520 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 21/111 (18%), Positives = 37/111 (33%), Gaps = 4/111 (3%) Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEIL 208 +P + K LAV+G G + A G +V + + A++ E Sbjct: 368 LPAVQKKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQF---NIAKQIPGKEEF 424 Query: 209 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAG 259 Y T+ + L++ +T + A G P T + G Sbjct: 425 YETLRYYRRMIEVTGVTLKLNHTVTAD-QLQAFDETILASGIVPRTPPIDG 474 >5U25-A nrPDB Length = 602 Score = 61.9 bits (149), Expect = 4e-10, Method: Composition-based stats. Identities = 47/230 (20%), Positives = 82/230 (35%), Gaps = 22/230 (9%) Query: 89 KVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGA 148 +V L++ + + V I+A G+ ++ E+ A A Sbjct: 245 EVSLTAGDAYEQAAPTGEKKIVAFKNCIIAAGSRVTKLPFIPEDPRIIDSSGALA----- 299 Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLR--ASTIMQKRAEKN---- 202 + K L + GG E + GS++ ++ D L A + K +K Sbjct: 300 LKEVPGKLLIIG-GGIIGLEMGTVYSTLGSRLDVVEMMDGLMQGADRDLVKVWQKQNEYR 358 Query: 203 -EKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV---A 258 + I + TVA+E K DG + + + A G P K++ Sbjct: 359 FDNIMVNTKTVAVEPKEDGVYVTF----EGANAPKEPQRYDAVLVAAGRAPNGKLISAEK 414 Query: 259 GQVDTDEAGYIKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAA 308 V + G+I+ V T+VP +A GD+ A + G +AA Sbjct: 415 AGVAVTDRGFIE-VDKQMRTNVPHIYAIGDIVGQPM-LAHKAVHEGHVAA 462 Score = 27.6 bits (60), Expect = 6.7, Method: Composition-based stats. Identities = 11/61 (18%), Positives = 26/61 (42%), Gaps = 2/61 (3%) Query: 66 ELMDRMREQST-KFGTEIITETVSKVD-LSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 +L+ ++Q+ +F ++ V+ + + N EP DA+++A G + Sbjct: 346 DLVKVWQKQNEYRFDNIMVNTKTVAVEPKEDGVYVTFEGANAPKEPQRYDAVLVAAGRAP 405 Query: 124 K 124 Sbjct: 406 N 406 >2TMD-A nrPDB Length = 729 Score = 60.0 bits (144), Expect = 1e-09, Method: Composition-based stats. Identities = 50/345 (14%), Positives = 106/345 (30%), Gaps = 70/345 (20%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGL 62 + V I+G+GP+ AA L + L + GG L ++ PG + Sbjct: 389 KDSVLIVGAGPSGSEAARVLMESGYTVHLTD----TAEKIGGHLN---QVAALPGLGEW- 440 Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFN----EDAEPVTTDAIILA 118 + + ++K+ +K +L +D D +I+A Sbjct: 441 --------------SYHRDYRETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIA 486 Query: 119 TGASAK--------RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDS---AC 167 TGA +PG + ++ V DG I K + ++ D+ A Sbjct: 487 TGARWNTDGTNCLTHDPIPGADASLPDQLTPEQVMDGKKKI--GKRVVILNA-DTYFMAP 543 Query: 168 EEAQFLTKYGSKVFM---LVRKDHLRASTIMQKRAEKNEKIEILY------------NTV 212 A+ L G +V + + +++ + + ++ + Sbjct: 544 SLAEKLATAGHEVTIVSGVHLANYMHFTLEYPNMMRRLHELHVEELGDHFCSRIEPGRME 603 Query: 213 ALEAKGDGKLLN----ALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGY 268 GDG + ++ + + L G + ++ E+ + Sbjct: 604 IYNIWGDGSKRTYRGPGVSPRDANTS-HRWIEFDSLVLVTGRHSECT-LWNELKARESEW 661 Query: 269 IKTVPGSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEK 313 + + G + GD R + +G A + E+ Sbjct: 662 AEND-------IKGIYLIGDA--EAPRLIADATFTGHRVAREIEE 697 Score = 36.5 bits (83), Expect = 0.016, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 34/108 (31%), Gaps = 5/108 (4%) Query: 153 RNKP-LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT 211 +NK + ++G G S E A+ L + G V + + + + + Sbjct: 387 KNKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHLNQVAALPGLGEWSYHRDY 446 Query: 212 VALEA----KGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK 255 + K + + AL K ++ + A G T Sbjct: 447 RETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIATGARWNTD 494 >5J7X-A nrPDB Length = 549 Score = 58.5 bits (140), Expect = 4e-09, Method: Composition-based stats. Identities = 36/217 (16%), Positives = 71/217 (32%), Gaps = 36/217 (16%) Query: 1 MVHNKVTIIGSGPAAHTAAIYL-----ARAEIKPILYE------GMMANGIAAGGQLTTT 49 ++H IIGSG + IYL ++K ++E G N G ++ Sbjct: 10 VLHLDALIIGSG----FSGIYLLHKLRDELKLKVKIFEAESDIGGTWNNNRYPGARVDCP 65 Query: 50 TEIENFPGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKP------------- 96 + P+ + Q + + V +V K Sbjct: 66 VPFYAY-SLPEVWQSWNWTELYPNQKE---IKSYFDHVDRVLDVRKDCLFHSRVNEGTFD 121 Query: 97 --FKLWTEFNEDAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIF 152 WT + D + T +++A G + + G +++ + + Sbjct: 122 EATGRWTVWTTDGKVATAKYLLVAVGFASKSYLPDWKGLDSFKGTIYHSAHWPEAEEISV 181 Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 + K +AVIG G + + Q + + F+ R +L Sbjct: 182 KGKKVAVIGTGSTGIQIFQEWAREAEEAFLFQRTPNL 218 >4OVI-A nrPDB Length = 542 Score = 57.7 bits (138), Expect = 7e-09, Method: Composition-based stats. Identities = 35/214 (16%), Positives = 66/214 (30%), Gaps = 37/214 (17%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 V ++G+G + A L + E GG +PG + Sbjct: 17 VDVLVVGAGFSGLYALYRLRELGRSVHVIE----TAGDVGGVWYWNR----YPGARCDIE 68 Query: 64 GSELMDRMREQS-------TKFGTE-----IITETVSKVDLSSKPF-------------- 97 E E+ ++ ++ I K DL S Sbjct: 69 SIEYCYSFSEEVLQEWNWTERYASQPEILRYINFVADKFDLRSGITFHTTVTAAAFDEAT 128 Query: 98 KLWTEFNEDAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNK 155 WT + + +I+A+G + + + PG + + V F + Sbjct: 129 NTWTVDTNHGDRIRARYLIMASGQLSVPQLPNFPGLKDFAGNLYHTGNWPHEPVD-FSGQ 187 Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 + VIG G S + + + K +++F+ R H Sbjct: 188 RVGVIGTGSSGIQVSPQIAKQAAELFVFQRTPHF 221 >6A37-A nrPDB Length = 552 Score = 56.5 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 34/206 (16%), Positives = 62/206 (30%), Gaps = 31/206 (15%) Query: 5 KVTIIGSGPAAHTAAIYLARA-----EIKPILYEGMMANGIA------AGGQLTTTTEIE 53 IIG+G +Y + +K ++ G G + T + Sbjct: 28 DAIIIGAG----FGGLYSLKKLRDDFNLKVRAFDRATEVGGTWFWNQYPGALSDSETHLY 83 Query: 54 NFPGFPDGLTGSELMDRMREQ----------STKFGT--EIITETVSKVDLSSKPFKLWT 101 + + L E+ + Q + K +I ET + + W Sbjct: 84 CYSWDKELLQEMEIKRKYISQPDVLAYLKRVADKHDLRKDIQFETGIRSAYFDEENSFWN 143 Query: 102 EFNEDAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAV 159 E+ E T +I A G A+ + G ET+ + F K + V Sbjct: 144 VTTENDEKFTARFLITALGLLAAPNLPKIKGIETFKGELHHTSRWPKDVT--FSGKRVGV 201 Query: 160 IGGGDSACEEAQFLTKYGSKVFMLVR 185 IG G + + + + + R Sbjct: 202 IGTGSTGVQVITAIASQVKHLTVFQR 227 >1LQU-A nrPDB Length = 456 Score = 55.4 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 41/198 (20%), Positives = 71/198 (35%), Gaps = 42/198 (21%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYE---GMMANGIAAGGQLTTTTEIENFPGFPDGL 62 + I+GSGP+A AA L +A + M+ G L + + P Sbjct: 6 IAIVGSGPSAFFAAASLLKAADTTEDLDMAVDMLEMLPTPWG-LVRSGVAPDHPKI---- 60 Query: 63 TGSELMDRMREQSTK-----FGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIIL 117 + + + + FG ++ E V +LS + DA+I Sbjct: 61 --KSISKQFEKTAEDPRFRFFGNVVVGEHVQPGELSER----------------YDAVIY 102 Query: 118 ATGASA-KRMHLPGEETYWQKG-------ISACAVCDGAVPIFRNKPLAVIGGGDSACEE 169 A GA + + +++PGE+ +A + P VIG G+ A + Sbjct: 103 AVGAQSDRMLNIPGEDLPGSIAAVDFVGWYNAHPHFEQVSPDLSGARAVVIGNGNVALDV 162 Query: 170 AQFLTKYGSKVFMLVRKD 187 A+ L + +L R D Sbjct: 163 ARILL---TDPDVLARTD 177 >6HNS-A nrPDB Length = 454 Score = 55.4 bits (132), Expect = 3e-08, Method: Composition-based stats. Identities = 46/236 (19%), Positives = 81/236 (34%), Gaps = 51/236 (21%) Query: 2 VHNKVTIIGSGPAAHT------------AAI-----------------YLARAEIKPI-- 30 ++ +V IIG+GP AAI Y R + Sbjct: 1 MNTRVAIIGAGPCGLAQLRAFQSAAAKGAAIPELVCFEKQSDWGGMWNYTWRTGVDEHGE 60 Query: 31 -----LYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSE--LMDRMREQSTKFGTEII 83 +Y + +NG + T E+F G P G L D ++ + K G Sbjct: 61 PVHGSMYRYLWSNGPKECLEFADYTFDEHF-GRPIGSYPPREVLWDYIKGRVEKAGVRDY 119 Query: 84 TETVSKV-----DLSSKPFKLWTEFNEDAEPVT--TDAIILATG--ASAKRMHLPGEETY 134 + V D +S F + + + + T D ++ A G ++ + G E + Sbjct: 120 IRFNTAVRQVSYDETSGLFSVTVQDHSNNRVYTETFDYVVNACGHFSTPNTPYFEGFERF 179 Query: 135 WQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGS-KVFMLVRKDHL 189 + + A D F++K + V+G SA + KYG+ + R + Sbjct: 180 GGRVLHAHDFRDALE--FKDKDILVVGSSYSAEDIGSQCYKYGARSITSCYRSAPM 233 >3K30-A nrPDB Length = 690 Score = 55.0 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 57/326 (17%), Positives = 105/326 (32%), Gaps = 67/326 (20%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 +V ++G+GP+ AA L +L E G GG++T + + PG Sbjct: 392 ARVLVVGAGPSGLEAARALGVRGYDVVLAEA----GRDLGGRVTQESAL---PGLSAWGR 444 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASA 123 E + + + EI E+ +D + +I ATGA+ Sbjct: 445 VKEYREAVLAELP--NVEIYRES--------------PMTGDDIVEFGFEHVITATGATW 488 Query: 124 KRMHLPGEETYWQ---KGISACAVCDGAVPIFR-NKPLAV-------IGGGDSACEEAQF 172 + + T +G+ D K + V +GG A+ Sbjct: 489 RTDGVARFHTTALPIAEGMQVLGPDDLFAGRLPDGKKVVVYDDDHYYLGG-----VVAEL 543 Query: 173 LTKYGSKVFMLV--------RKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLN 224 L + G +V ++ + + I Q+R +N + + V Sbjct: 544 LAQKGYEVSIVTPGAQVSSWTNNTFEVNRI-QRRLIENGVARVTDHAVVA------VGAG 596 Query: 225 ALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPGSSLTSVPGFF 284 + +++T + E +L + P ++ V +AG I +V G Sbjct: 597 GVTVRDTYASIERELECDAVVMVTARLPREELYLDLVARRDAGEIASVRG---------- 646 Query: 285 AAGDVQDSKYRQAITSAGSGCMAALD 310 GD + SG AA + Sbjct: 647 -IGDA--WAPGTIAAAVWSGRRAAEE 669 >6ER9-A nrPDB Length = 549 Score = 55.0 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 48/128 (37%), Gaps = 6/128 (4%) Query: 62 LTGSELMDRMREQSTKFGTEIITETVSKVDLSS--KPFKLWTEFNEDAEPVTTDAIILAT 119 +T E+++ + +F ++V + + LW + E ++ A Sbjct: 85 ITQPEILEYLESVVDRFDLRRHFRFGTEVTSAIYLEDENLWEVSTDKGEVYRAKYVVNAV 144 Query: 120 G--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYG 177 G ++ LPG +T+ + I A +G K + VIG G + + L Sbjct: 145 GLLSAINFPDLPGLDTFEGETIHTAAWPEG--KNLAGKRVGVIGTGSTGQQVITALAPEV 202 Query: 178 SKVFMLVR 185 + + VR Sbjct: 203 EHLTVFVR 210 >5JWC-A nrPDB Length = 521 Score = 54.6 bits (130), Expect = 5e-08, Method: Composition-based stats. Identities = 41/234 (17%), Positives = 75/234 (32%), Gaps = 55/234 (23%) Query: 102 EFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFR-------- 153 + + + D +I+A GA ++ G + Y D A+ I + Sbjct: 119 DIENNKVKLFYDYLIIAVGAKTNTFNINGVDKYA----YFVKDIDDALKIRKKFLDILEK 174 Query: 154 ---------NKP----LAVIGGGDSACEE-AQFLTKYGSKVFMLVR-------------K 186 K +AV+GGG + E A+F +V + + Sbjct: 175 CTLPNISNEEKKKMLHVAVVGGGPTGVEVTAEFADFINKEVKINYKDIFNFISISIIEGG 234 Query: 187 DHLRAS-----TIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPV 241 ++L + + K N I +L N ++ + + + KNE+ L Sbjct: 235 NNLLPTFTQNISDFTKENFHNLNINVLTNYYVIDVDKHSFHIQS----SLNKNEKKKLSY 290 Query: 242 SGLFYAIGHTPATKIVAGQVDT---DEAGYIKTVPGSSLT-SVP--GFFAAGDV 289 L +A G T ++ + T I V +P +A GD Sbjct: 291 GLLIWASGLA-QTTLIQKFLKTIPVQANNAILKVDEKLRVIGIPSNNIYAIGDC 343 >5KVH-A nrPDB Length = 543 Score = 54.2 bits (129), Expect = 7e-08, Method: Composition-based stats. Identities = 40/235 (17%), Positives = 80/235 (34%), Gaps = 35/235 (14%) Query: 74 QSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEE 132 G ++T V ++D+ KL D +T + ++ATG + + + Sbjct: 143 HIENGGVAVLTGKKVVQLDVRDNMVKL-----NDGSQITYEKCLIATGGTPRSL---SAI 194 Query: 133 TYWQKGISACAVCDGAVPIFRN--------KPLAVIGGGDSACEEAQFL----TKYGSKV 180 + + + FR+ K + +IGGG E A L G++V Sbjct: 195 DRAGAEVKSRTTLFRKIGDFRSLEKISREVKSITIIGGGFLGSELACALGRKARALGTEV 254 Query: 181 FMLV----RKDHLRASTIMQKRAEK--NEKIEILYNTVALEAKGDGKLLNALRIKNTKKN 234 L + + EK E ++++ N + L +++K+ +K Sbjct: 255 IQLFPEKGNMGKILPEYLSNWTMEKVRREGVKVMPNAIVQSVGVSSGKL-LIKLKDGRK- 312 Query: 235 EETDLPVSGLFYAIGHTPATKIVA-GQVDTDEAGYIKTVPGSSLTSVPGFFAAGD 288 + + A+G P ++ G ++ D V + AGD Sbjct: 313 ----VETDHIVAAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA-RSNIWVAGD 362 >4RG3-A nrPDB Length = 548 Score = 54.2 bits (129), Expect = 7e-08, Method: Composition-based stats. Identities = 34/203 (16%), Positives = 68/203 (33%), Gaps = 23/203 (11%) Query: 4 NKVTIIGSGPAAHTAAIYLA-RAEIKPILYEGMMANGIA------AGGQLTTTTEIENFP 56 +IG+G A L + + ++ G G T + + F Sbjct: 17 VDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWYWNRYPGALSDTESHLYRFS 76 Query: 57 GFPD----------GLTGSELMDRMREQSTKFGTEIITETVSKVD--LSSKPFKLWTEFN 104 D +T E+++ + + +F + ++V L LW Sbjct: 77 FDRDLLQESTWKTTYITQPEILEYLEDVVDRFDLRRHFKFGTEVTSALYLDDENLWEVTT 136 Query: 105 EDAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGG 162 + E ++ A G ++ +LPG +T+ + I A +G + + VIG Sbjct: 137 DHGEVYRAKYVVNAVGLLSAINFPNLPGLDTFEGETIHTAAWPEG--KSLAGRRVGVIGT 194 Query: 163 GDSACEEAQFLTKYGSKVFMLVR 185 G + + L + + VR Sbjct: 195 GSTGQQVITSLAPEVEHLTVFVR 217 >6JDK-A nrPDB Length = 544 Score = 52.7 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 37/223 (16%), Positives = 67/223 (30%), Gaps = 37/223 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG------IAAGGQLTTTTEIENFPGF 58 I+G+G L + K L+E G G ++ + I F Sbjct: 19 DALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGGIWYWNCYPGARVDSHIPIYEFS-- 76 Query: 59 PDGLTGSELMDRMREQSTKFGT----EIITETVSKVDLSSKPFKL--------------- 99 E + R + +F V K S+ + Sbjct: 77 ------IEELWRDWNWTERFPAWDELRRYFHYVDKKLDLSRDIRFGMRVSAAEFDEARDQ 130 Query: 100 WTEFNEDAEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPL 157 W D V IL TG + + G E++ + + F K + Sbjct: 131 WVIRTTDGTVVRARFFILCTGFASKPYIPNYKGLESFAGESFHT-GLWPQEGASFTGKRV 189 Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAE 200 V+G G S + Q +K + + + R + A + Q++ + Sbjct: 190 GVVGTGASGVQVVQEASKDAAHLTVFQR-TPILALPMQQRKLD 231 >4AP1-A nrPDB Length = 549 Score = 51.1 bits (121), Expect = 6e-07, Method: Composition-based stats. Identities = 31/201 (15%), Positives = 68/201 (33%), Gaps = 21/201 (10%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG------IAAGGQLTTTTEIENFPGF 58 V ++G+G A A + +E G G + + ++ Sbjct: 23 DVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGGVWYWNRYPGARCDVESIDYSYSFS 82 Query: 59 PD----------GLTGSELMDRMREQSTKFGT--EIITETVSKVDLSSKPFKLWTEFNED 106 P+ T E++ + + +F +I +T + + WT + Sbjct: 83 PELEQEWNWSEKYATQPEILAYLEHVADRFDLRRDIRFDTRVTSAVLDEEGLRWTVRTDR 142 Query: 107 AEPVTTDAIILATG--ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGD 164 + V+ +++A G ++A G + + + V F K + VIG G Sbjct: 143 GDEVSARFLVVAAGPLSNANTPAFDGLDRFTGDIVHTARWPHDGVD-FTGKRVGVIGTGS 201 Query: 165 SACEEAQFLTKYGSKVFMLVR 185 S + + + ++F+ R Sbjct: 202 SGIQSIPIIAEQAEQLFVFQR 222 >2GV8-A nrPDB Length = 447 Score = 49.6 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 48/305 (15%), Positives = 96/305 (31%), Gaps = 81/305 (26%) Query: 5 KVTIIGSGPAAH-TA-AIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFP--- 59 K+ IIG+GP+ TA A+ +A + L+E + GG T+ + N P Sbjct: 8 KIAIIGAGPSGLVTAKALLAEKAFDQVTLFE----RRGSPGGVWNYTSTLSNKLPVPSTN 63 Query: 60 -----DGLTGS--------------------ELM----DRMREQSTKFGTEIITET---- 86 + + G ELM + Q+ +F + Sbjct: 64 PILTTEPIVGPAALPVYPSPLYRDLQTNTPIELMGYCDQSFKPQTLQFPHRHTIQEYQRI 123 Query: 87 --------------VSKVDLSSKPFKLWTEFNEDAEPVT---TDAIILATG--ASAKRMH 127 V ++ + + + + P++ DA+ + G + Sbjct: 124 YAQPLLPFIKLATDVLDIEKKDGSWVVTYKGTKAGSPISKDIFDAVSICNGHYEVPYIPN 183 Query: 128 LPGEETYWQ--KGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVR 185 + G + Y + G + +F + + V+GG SA + + LT + + Sbjct: 184 IKGLDEYAKAVPGSVLHSSLFREPELFVGESVLVVGGASSANDLVRHLTPVAKHP--IYQ 241 Query: 186 KDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLF 245 L I + ++ +I T GK+L+ + + Sbjct: 242 S-LLGGGDIQNESLQQVPEITKFDPTTREIYLKGGKVLS---------------NIDRVI 285 Query: 246 YAIGH 250 Y G+ Sbjct: 286 YCTGY 290 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 9/34 (26%), Positives = 17/34 (50%), Gaps = 2/34 (5%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGS--KVFMLVRK 186 + +A+IG G S A+ L + +V + R+ Sbjct: 7 RKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERR 40 >2XVH-A nrPDB Length = 464 Score = 49.2 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 47/320 (14%), Positives = 92/320 (28%), Gaps = 71/320 (22%) Query: 4 NKVTIIGSGPAAHTA--AIYLARAEIKPILYEGMMANGIAAGGQLTTTTEI---ENFPGF 58 ++ I+G+GP+ A A+ + I GGQ T EN G Sbjct: 3 TRIAILGAGPSGMAQLRAFQSAQEKGAEIPELVCFEKQADWGGQWNYTWRTGLDEN--GE 60 Query: 59 PDGLT--------GSE---------LMDRMREQSTKFGT-EIITETVSKVDLSSKPFKL- 99 P + G + + + + E++ + + + K Sbjct: 61 PVHSSMYRYLWSNGPKECLEFADYTFDEHFGKPIASYPPREVLWDYIKGRVEKAGVRKYI 120 Query: 100 -------WTEFNEDAEPVT---------------TDAIILATG--ASAKRMHLPGEETYW 135 EFNED++ T D ++ TG ++ G E + Sbjct: 121 RFNTAVRHVEFNEDSQTFTVTVQDHTTDTIYSEEFDYVVCCTGHFSTPYVPEFEGFEKFG 180 Query: 136 QKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIM 195 + + A D F++K + ++G SA + KYG+K L + Sbjct: 181 GRILHAHDFRDALE--FKDKTVLLVGSSYSAEDIGSQCYKYGAK--------KLISCYRT 230 Query: 196 QKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATK 255 K + E L + +N + + V + G+ Sbjct: 231 APMGYK-------WPENWDE----RPNLVRVDTENAYFADGSSEKVDAIILCTGYIHHFP 279 Query: 256 IVAGQVDTDEAGYIKTVPGS 275 + + + + Sbjct: 280 FLNDDLRLVTNNRLWPLNLY 299 >5GSN-A nrPDB Length = 453 Score = 48.1 bits (113), Expect = 6e-06, Method: Composition-based stats. Identities = 49/321 (15%), Positives = 96/321 (29%), Gaps = 75/321 (23%) Query: 5 KVTIIGSGPAAH-------TAA----------------------IYLARAEI-------K 28 +V +IG+GP+ +AA Y R + Sbjct: 4 RVAVIGAGPSGLAQLRAFQSAADQGAEIPEIVCFEKQANWGGLWNYTWRTGLDENGEPVH 63 Query: 29 PILYEGMMANGIAAGGQLTTTTEIENF----PGFPDGLTGSELMDRMREQST-----KFG 79 +Y + +NG G + + E+F +P + ++ ++ +F Sbjct: 64 CSMYRYLWSNGPKEGLEFADYSFEEHFGKQIASYPPRAVLFDYIEGRVHKADVRKWIRFN 123 Query: 80 TEIITETVSKVDLSSKPFKLWTEFNEDAEPVTT--DAIILATG--ASAKRMHLPGEETYW 135 + + D + F + +E + D +I A+G ++ G +T+ Sbjct: 124 SPVRW---VSYDAETAKFTVTAHNHETDSTYSAAFDHVICASGHFSTPNVPFYEGFDTFN 180 Query: 136 QKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSK-VFMLVRKDHLRASTI 194 + + A D F K + V+G SA + KYG+K + R + Sbjct: 181 GRIVHAHDFRDARE--FEGKDVLVMGASSSAEDIGSQCWKYGAKSITSCYRSAPM--GYA 236 Query: 195 MQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPAT 254 E+ +E L A A G + V + G+ Sbjct: 237 WPDNWEEKPALEKLTGKTAHFADG------------------STRDVDAIILCTGYKHFF 278 Query: 255 KIVAGQVDTDEAGYIKTVPGS 275 + + A + T Sbjct: 279 SFLPDDLRLKTANRLATADLY 299 >3H8L-A nrPDB Length = 409 Score = 47.3 bits (111), Expect = 8e-06, Method: Composition-based stats. Identities = 66/355 (18%), Positives = 107/355 (30%), Gaps = 76/355 (21%) Query: 4 NKVTIIGSGPAAHTAAIYLAR-----AEIKPILYEGMMANGIAAGGQLTTTTEIENFPGF 58 KV ++G A TAA L R A++K I A +++ Sbjct: 2 TKVLVLGGRFGALTAAYTLKRLVGSKADVKVINKSRFSYFRPALPHVAIGVRDVD----- 56 Query: 59 PDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 EL + E + G + TV K+D S AE D +I+ Sbjct: 57 -------ELKVDLSEALPEKGIQFQEGTVEKIDAKSSMVYYTKPDGSMAEE-EYDYVIVG 108 Query: 119 TGASAKRMHLPGEETYWQKGISAC-----AVCDGAVPIFRNKPLAVIGGG---------- 163 GA + G + Y G S C + F+ +A IG G Sbjct: 109 IGAHLATELVKGWDKY---GYSVCEPEFATKLREKLESFQGGNIA-IGSGPFYQGHNPKP 164 Query: 164 ----------DSACE-----EAQFLTKYGSK--------VFMLVRKDHLRASTIMQKRA- 199 DSACE + L Y K V + ++L + ++A Sbjct: 165 KVPENFVPNADSACEGPVFEMSLMLHGYFKKKGMLDKVHVTVFSPGEYLSDLSPNSRKAV 224 Query: 200 ---EKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKI 256 I++++N E R + +P +T + Sbjct: 225 ASIYNQLGIKLVHNFKIKEI----------REHEIVDEKGNTIPADITILLPPYTGNPAL 274 Query: 257 VAGQVDT-DEAGYIKTVPGSSLTSVPGFFAAGDVQD-SKYRQAITSAGSGCMAAL 309 D D+ G+I T +A GD + + + +G +AA Sbjct: 275 KNSTPDLVDDGGFIPTDLNMVSIKYDNVYAVGDANSMTVPKLGYLAVMTGRIAAQ 329 >5MIU-A nrPDB Length = 535 Score = 46.9 bits (110), Expect = 1e-05, Method: Composition-based stats. Identities = 41/227 (18%), Positives = 77/227 (33%), Gaps = 29/227 (12%) Query: 79 GTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQK 137 G ++T V +D+ KL D +T + ++ATG + + + K Sbjct: 146 GVAVLTGKKVVHLDVRGNMVKL-----NDGSQITFEKCLIATGGTPRSLSAIDRAGAEVK 200 Query: 138 GISACAVCDGAVPIF-----RNKPLAVIGGGDSACEEAQFLTKY----GSKVFMLVRKDH 188 + G K + VIG G E A L + G +V L + Sbjct: 201 SRTTLFRKIGDFRALEKISREVKSITVIGEGFLGSELACALGRKSQASGIEVIQLFPEKG 260 Query: 189 LRASTIMQKRAE------KNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVS 242 + Q + K E ++++ N + G L +++K+ +K + Sbjct: 261 NMGKILPQYLSNWTMEKVKREGVKVMPNAIVQSVGVSGGRL-LIKLKDGRK-----VETD 314 Query: 243 GLFYAIGHTPATKIVA-GQVDTDEAGYIKTVPGSSLTSVPGFFAAGD 288 + A+G P ++ G ++ D V + AGD Sbjct: 315 HIVTAVGLEPNVELAKTGGLEIDSDFGGFRVNAELQA-RSNIWVAGD 360 >3T14-A nrPDB Length = 437 Score = 44.2 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 59/308 (19%), Positives = 99/308 (32%), Gaps = 57/308 (18%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG- 64 V I+G+G AA E+K L G ++ + P P G Sbjct: 7 VVILGAGTGGMPAA-----YEMKEALGSGHEVTL------ISANDYFQFVPSNPWVGVGW 55 Query: 65 ---SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGA 121 ++ +R + G I ++ ++D ++ L D V D +++ATG Sbjct: 56 KERDDIAFPIRHYVERKGIHFIAQSAEQIDAEAQNITL-----ADGNTVHYDYLMIATGP 110 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIF-------RNKPLAVIG--GGDS------- 165 ++PG + + + + A D A F R VIG G S Sbjct: 111 KLAFENVPGSDPHEGP-VQSIATVDHAERAFAEYQALLREPGPIVIGAMAGASCFGPAYE 169 Query: 166 -ACEEAQFLTKYG------------SKVFMLVRKDH-LRASTIMQKRAEKNEKIEILYNT 211 A A L K G S+ ++ + S + + K E IE N Sbjct: 170 YAMIVASDLKKRGMRDKIPSFTFITSEPYIGHLGIQGVGDSKGILTKGLKEEGIEAYTNC 229 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETDLPV--SGLFYAIGHTPATKIVAGQVDTDEAGYI 269 + + + + + + + +E LPV + A PA V G G Sbjct: 230 KVTKVEDNKMYVTQVD-EKGETIKEMVLPVKFGMMIPAFKGVPAVAGVEG---LCNPGGF 285 Query: 270 KTVPGSSL 277 V Sbjct: 286 VLVDEHQR 293 >4Y4N-A nrPDB Length = 286 Score = 43.0 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 22/37 (59%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 ++ V I+G GP+ TAA Y+A+ K ++ E +A Sbjct: 50 IIDVDVAIVGGGPSGLTAARYIAKEGYKVVVLERHLA 86 Score = 37.7 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 17/90 (18%), Positives = 34/90 (37%), Gaps = 11/90 (12%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE 215 +A++GGG S A+++ K G KV +L R T + + +E Sbjct: 54 DVAIVGGGPSGLTAARYIAKEGYKVVVLERHLAFGGGTWGGGMG---------FPYIVVE 104 Query: 216 AKGDGKLLN-ALRIKNTKKNEETDLPVSGL 244 D L ++++ + E+ + Sbjct: 105 EPADEILREVGVKLEKVE-GEDGLYTADSV 133 >4Y4M-A nrPDB Length = 290 Score = 42.7 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 22/37 (59%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 +V V I+G+GP+ T A YLA+ K ++ E +A Sbjct: 57 IVEADVVIVGAGPSGLTCARYLAKEGFKVVVLERHLA 93 Score = 35.3 bits (80), Expect = 0.035, Method: Composition-based stats. Identities = 14/61 (22%), Positives = 23/61 (37%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE 215 + ++G G S A++L K G KV +L R T +E + + E Sbjct: 61 DVVIVGAGPSGLTCARYLAKEGFKVVVLERHLAFGGGTWGGGMGFPYIVVEEPADELLRE 120 Query: 216 A 216 Sbjct: 121 V 121 >1Y56-A nrPDB Length = 493 Score = 41.9 bits (97), Expect = 3e-04, Method: Composition-based stats. Identities = 46/267 (17%), Positives = 81/267 (30%), Gaps = 58/267 (21%) Query: 29 PILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG--SELMDRMREQSTKFGTEIITET 86 ++ E GG + + GF EL+ ++ E T+I ET Sbjct: 134 ALIEERG-----WLGGDMWLKGIKQE--GFNKDSRKVVEELVGKLNE-----NTKIYLET 181 Query: 87 -VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVC 145 V + F + + + ++LATGA M + G+ Sbjct: 182 SALGVFDKGEYFLVPVVRGDKLIEILAKRVVLATGAIDSTMLFENND---MPGVFRRDFA 238 Query: 146 DGAVPIF---RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKN 202 + ++ + +AV G A E Q L ++G Sbjct: 239 LEVMNVWEVAPGRKVAVTGS--KADEVIQELERWG------------------------- 271 Query: 203 EKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV--AGQ 260 I+ ++ +G+ K+ + + N + V L +A G P + AG Sbjct: 272 --IDYVHIPNVKRVEGNEKVERVIDMNNH------EYKVDALIFADGRRPDINPITQAGG 323 Query: 261 VDTDEAGYIKTVPGSSLTSVPGFFAAG 287 GY V G + AG Sbjct: 324 KLRFRRGYYSPVLDEYHRIKDGIYVAG 350 >3NK2-X nrPDB Length = 431 Score = 41.5 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 21/80 (26%), Positives = 33/80 (41%), Gaps = 9/80 (11%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 ++G G + AA L A K +L EG G GG+ + E N PG + G Sbjct: 3 DAIVVGGGFSGLKAARDLTNAGKKVLLLEG----GERLGGR-AYSRESRNVPGLRVEIGG 57 Query: 65 SELMD----RMREQSTKFGT 80 + L R+ + ++G Sbjct: 58 AYLHRKHHPRLAAELDRYGI 77 Score = 33.0 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 20/40 (50%) Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK 197 V+GGG S + A+ LT G KV +L + L ++ Sbjct: 5 IVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRE 44 >3RHA-A nrPDB Length = 482 Score = 41.5 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 12/35 (34%), Positives = 18/35 (51%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG 39 V I+G+GP+ TAA L +A + + E G Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVG 43 Score = 36.1 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 ++ + ++G G S A+ L K G V +L +D Sbjct: 7 DRDVVIVGAGPSGLTAARELKKAGLSVAVLEARDR 41 >4TLZ-A nrPDB Length = 443 Score = 41.5 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 35/196 (17%), Positives = 56/196 (28%), Gaps = 29/196 (14%) Query: 13 PAAHTAAIYLARAEIKPILYEGMMANGIAAG------------------------GQLTT 48 PAA T+A + RA I + A + G+L Sbjct: 53 PAALTSAFFERRASISWHQGMLLPAAKMQVSFLKDLATFRNPASRFSFVSFLHERGRLVR 112 Query: 49 TTEIENF-PGFPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDA 107 +F P + E + + +E+ T + E Sbjct: 113 FANNHDFFPTRREFHDYLEWAESKLAHEVSYDSEV-TAIRPGPGRPVDSVLVDVSTPEAT 171 Query: 108 EPVTTDAIILATGASAKRM-HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSA 166 V I+++TG + + +E W D R +AV GGG SA Sbjct: 172 RTVEARNIVISTGLVPRMPAGVQSDEFVWHSSRFLDHFRDRDPRSLR--RVAVAGGGQSA 229 Query: 167 CEEAQFLTKYGSKVFM 182 E +FL + Sbjct: 230 AEIVRFLHDNRPDTVV 245 >4B68-A nrPDB Length = 501 Score = 41.5 bits (96), Expect = 5e-04, Method: Composition-based stats. Identities = 35/145 (24%), Positives = 58/145 (40%), Gaps = 20/145 (13%) Query: 66 ELMDRMREQSTKF-GTEIITETVSKV-----DLSSKPFKLWTEFNEDAEP-----VTTDA 114 E D MR + +F E V +V D SS +T + + E T Sbjct: 146 EFEDYMRWCAQQFSDVVAYGEEVVEVIPGKSDPSSSVVDFFTVRSRNVETGEISARRTRK 205 Query: 115 IILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKP----LAVIGGGDSACEEA 170 +++A G +AK +P + I + C + ++K +AV+G G SA E Sbjct: 206 VVIAIGGTAK---MPSGLPQDPRIIHSSKYCTTLPALLKDKSKPYNIAVLGSGQSAAEIF 262 Query: 171 QFLTKY--GSKVFMLVRKDHLRAST 193 L K S+ +++R +R S Sbjct: 263 HDLQKRYPNSRTTLIMRDSAMRPSD 287 >3LOV-A nrPDB Length = 475 Score = 41.1 bits (95), Expect = 7e-04, Method: Composition-based stats. Identities = 29/136 (21%), Positives = 47/136 (34%), Gaps = 22/136 (16%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE----IENFP 56 M ++ I+G G AA Y RA P L ++ G GG++ T E IE P Sbjct: 2 MSSKRLVIVGGGITGLAAAYYAERAF--PDLNITLLEAGERLGGKVATYREDGFTIERGP 59 Query: 57 -----------GFPDGL-TGSELMDRMREQSTKFGT----EIITETVSKVDLSSKPFKLW 100 + + G +L+ Q+ T I V + F+ Sbjct: 60 DSYVARKHILTDLIEAIGLGEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLDLFRQT 119 Query: 101 TEFNEDAEPVTTDAII 116 T E+ + D ++ Sbjct: 120 TLLTEEEKQEVADLLL 135 >4G74-A nrPDB Length = 502 Score = 40.7 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 59/335 (17%), Positives = 110/335 (32%), Gaps = 59/335 (17%) Query: 6 VTIIGSGPAAHT--AAIYLARAEIKPI----LYEGMMANGIAAGGQLTTTTEIENFPGFP 59 V I+GSG A + I + + I + A G + + IE F Sbjct: 45 VLILGSGWGAISFLKHIDTKKYNVSIISPRSYFLFTPLLPSAPVGTVDEKSIIEPIVNFA 104 Query: 60 DGLTGSELMDRMREQSTKFGTE---IITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAII 116 G+ + ++T + + +++S V +P + + D +I Sbjct: 105 LKKKGN--VTYYEAEATSINPDRNTVTIKSLSAVSQLYQPENHLGLHQAEPAEIKYDYLI 162 Query: 117 LATGASAKRMHLPGEETY--WQKGI--------SACAVCDGAVPIFRN----KPLAVI-- 160 A GA +PG Y + K I + A + A + + + L I Sbjct: 163 SAVGAEPNTFGIPGVTDYGHFLKEIPNSLEIRRTFAANLEKANLLPKGDPERRRLLSIVV 222 Query: 161 ---------GGG----DSACEEAQFLTKYGSKV--FMLVRKD------HLRASTIMQKRA 199 G + +FL +V ++ + S+ Q Sbjct: 223 VGGGPTGVEAAGELQDYVHQDLRKFLPALAEEVQIHLVEALPIVLNMFEKKLSSYAQSHL 282 Query: 200 EKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPA---TKI 256 +N I++ T + + + +LL + ++ K EET +P L +A G+ T + Sbjct: 283 -ENTSIKVHLRTAVAKVE-EKQLLAKTKHEDGKITEET-IPYGTLIWATGNKARPVITDL 339 Query: 257 VAGQVDTDEAGYIKTVPGSSLTSVPG---FFAAGD 288 + + + V V G FA GD Sbjct: 340 FKKIPEQNSSKRGLAVNDFLQ--VKGSNNIFAIGD 372 >2UZZ-A nrPDB Length = 372 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 24/140 (17%), Positives = 44/140 (31%), Gaps = 8/140 (5%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPG---- 57 + + IIGSG A Y RA + ++ + M G T I + G Sbjct: 1 MKYDLIIIGSGSVGAAAGYYATRAGLNVLMTDAHMPP-HQHGSHHGDTRLIRHAYGEGEK 59 Query: 58 -FPDGLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAII 116 P L L D + + + V + + F + + + + + Sbjct: 60 YVPLVLRAQMLWDELSRHNED-DPIFVRSGVINLGPADSTFLANVAHSAEQWQLNVEKL- 117 Query: 117 LATGASAKRMHLPGEETYWQ 136 A G A+ + + Y Sbjct: 118 DAQGIMARWPEIRVPDNYIG 137 >3ATQ-A nrPDB Length = 453 Score = 40.4 bits (93), Expect = 0.001, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 20/45 (44%), Gaps = 2/45 (4%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYE--GMMANGIAAGG 44 + V IIG G A +AA L+R +K +L + G G Sbjct: 5 LKYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCG 49 >3WE0-A nrPDB Length = 580 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 40/117 (34%), Gaps = 22/117 (18%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 +V I+G+G A AA L + +KP++YE G Q T+ G L G Sbjct: 67 EVAIVGAGIAGLVAAYELMKLGLKPVVYEA-SKMGGRLRSQAFNGTD-----GIIAELGG 120 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFK-------LWTEFNEDAEPVTTDA 114 + V K+ L +KPF T + + + + Sbjct: 121 MRF---------PVSSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTYYAEK 168 Score = 31.5 bits (70), Expect = 0.56, Method: Composition-based stats. Identities = 21/134 (15%), Positives = 36/134 (26%), Gaps = 13/134 (9%) Query: 118 ATGASAKR---MHLPGEETYWQKGISACAVCDGAVPIFR-NKPLAVIGGGDSACEEAQFL 173 A G P W + G++P R + +A++G G + A L Sbjct: 29 ADGKKPITIFGPDFPFAFDDWLE----HPAGLGSIPAARHGEEVAIVGAGIAGLVAAYEL 84 Query: 174 TKYGSKVFMLVR---KDHLRASTIM--QKRAEKNEKIEILYNTVALEAKGDGKLLNALRI 228 K G K + LR+ + + ++ A D L Sbjct: 85 MKLGLKPVVYEASKMGGRLRSQAFNGTDGIIAELGGMRFPVSSTAFYHYVDKLGLETKPF 144 Query: 229 KNTKKNEETDLPVS 242 N + Sbjct: 145 PNPLTPASRSTVID 158 >2JB2-A nrPDB Length = 489 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 13/47 (27%), Positives = 21/47 (44%), Gaps = 4/47 (8%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTT 50 + V ++G GPA +A L +A K + E GG++ T Sbjct: 12 HSVVVLGGGPAGLCSAFELQKAGYKVTVLEA----RTRPGGRVWTAR 54 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 16/32 (50%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 + V+GGG + A L K G KV +L + Sbjct: 14 VVVLGGGPAGLCSAFELQKAGYKVTVLEARTR 45 >1F8S-A nrPDB Length = 498 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 47/279 (16%), Positives = 82/279 (29%), Gaps = 58/279 (20%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I+G+G A +AA LA A + + E GG++ T E G+ L Sbjct: 36 VVIVGAGMAGLSAAYVLAGAGHQVTVLEA----SERPGGRVRTYRNEE--AGWYANLGPM 89 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKR 125 L ++ R I+ E + K DL F D I G K Sbjct: 90 RLPEKHR---------IVREYIRKFDLRLNEF----SQENDNAWYFIKNIRKKVGEVKKD 136 Query: 126 MHL------PGE---------ETYWQKGI-----SACAVCDGAVPIFRNKPLAVIGGGDS 165 L P E E K + + C+ + K + G S Sbjct: 137 PGLLKYPVKPSEAGKSAGQLYEESLGKVVEELKRTNCSYILNKYDTYSTKEYLIKEGDLS 196 Query: 166 --ACEEAQFLTK--YGSKVFMLVRK---DHLRASTIMQKRAEKNEKI----------EIL 208 A + L G V + D + + +K+ ++ Sbjct: 197 PGAVDMIGDLLNEDSGYYVSFIESLKHDDIFAYEKRFDEIVDGMDKLPTAMYRDIQDKVH 256 Query: 209 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYA 247 +N ++ + + + + + T E + + Sbjct: 257 FNAQVIKIQQNDQKVTVVY--ETLSKETPSVTADYVIVC 293 Score = 30.7 bits (68), Expect = 0.78, Method: Composition-based stats. Identities = 8/34 (23%), Positives = 15/34 (44%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 K + ++G G + A L G +V +L + Sbjct: 34 KHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASER 67 >1E1N-A nrPDB Length = 460 Score = 40.0 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 28/180 (15%), Positives = 59/180 (32%), Gaps = 34/180 (18%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 ++ ++GSGPA A +L + + + + + G L + P + + Sbjct: 8 QICVVGSGPAGFYTAQHLLKHHSRAHV-DIYEKQLVPFG--LVRFGVAPDHPEVKNVI-- 62 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGAS-A 123 Q+ + V + + + A++L+ GA Sbjct: 63 -----NTFTQTARSDRCAFYGNVEV----GRDVTVQELQDA------YHAVVLSYGAEDH 107 Query: 124 KRMHLPGEETYWQKGISACAVCDGA----------VPIFRNKPLAVIGGGDSACEEAQFL 173 + + +PGEE G+ + G P ++G G+ A + A+ L Sbjct: 108 QALDIPGEEL---PGVFSARAFVGWYNGLPENRELAPDLSCDTAVILGQGNVALDVARIL 164 >4A6N-B nrPDB Length = 398 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 21/101 (20%), Positives = 38/101 (37%), Gaps = 11/101 (10%) Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTI----------MQKR 198 + + +K +A+IGGG A+ L + G V + R + A Q+ Sbjct: 21 MNLLSDKNVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIFGGTLDLHKGSGQEA 80 Query: 199 AEKNEKIEILYN-TVALEAKGDGKLLNALRIKNTKKNEETD 238 +K ++ Y+ + + + N L KN K D Sbjct: 81 MKKAGLLQTYYDLALPMGVNIADEKGNILSTKNVKPENRFD 121 Score = 33.8 bits (76), Expect = 0.089, Method: Composition-based stats. Identities = 12/28 (42%), Positives = 14/28 (50%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYE 33 V IIG GP T A L + I +YE Sbjct: 29 VAIIGGGPVGLTMAKLLQQNGIDVSVYE 56 >1ZOV-A nrPDB Length = 386 Score = 39.6 bits (91), Expect = 0.002, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 17/35 (48%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 H V ++G+G A YLA+ +K +L + Sbjct: 3 HFDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDP 37 Score = 28.4 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 13/33 (39%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 + V+G G +L K G K ++ D Sbjct: 5 DVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDP 37 >3ABT-A nrPDB Length = 662 Score = 39.2 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 19/40 (47%) Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 +P + + +IG G S A+ L +G V +L +D Sbjct: 102 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 141 Score = 31.9 bits (71), Expect = 0.34, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 15/35 (42%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG 39 KV IIGSG + AA L + L E G Sbjct: 109 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVG 143 >5L3D-A nrPDB Length = 852 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 11/40 (27%), Positives = 19/40 (47%) Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 +P + + +IG G S A+ L +G V +L +D Sbjct: 273 LPTKKTGKVIIIGSGVSGLAAARQLQSFGMDVTLLEARDR 312 Score = 31.9 bits (71), Expect = 0.41, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 15/35 (42%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG 39 KV IIGSG + AA L + L E G Sbjct: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVG 314 >3CP8-A nrPDB Length = 641 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 33/151 (21%), Positives = 53/151 (35%), Gaps = 37/151 (24%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYE------GMMANGIAAGGQLTT--TTEIENFP 56 V ++G+G A AA+ +AR + +L M+ A GG T EI+ Sbjct: 23 DVIVVGAGHAGCEAALAVARGGLHCLLITSDLSAVARMSCNPAIGGVAKGQITREIDALG 82 Query: 57 G-FPDGLTGSELMDRM------------REQSTKF--------------GTEIITETVSK 89 G + + + RM R Q+ K +++ +TV Sbjct: 83 GEMGKAIDATGIQFRMLNRSKGPAMHSPRAQADKTQYSLYMRRIVEHEPNIDLLQDTVIG 142 Query: 90 VDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 V +S F T + + A ILA G Sbjct: 143 VSANSGKFSSVTVRS--GRAIQAKAAILACG 171 >3HWR-A nrPDB Length = 318 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 17/86 (19%), Positives = 39/86 (45%), Gaps = 3/86 (3%) Query: 151 IFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKN---EKIEI 207 F+ +A++G G C L + G +V ++ R H++A R E E++++ Sbjct: 16 YFQGMKVAIMGAGAVGCYYGGMLARAGHEVILIARPQHVQAIEATGLRLETQSFDEQVKV 75 Query: 208 LYNTVALEAKGDGKLLNALRIKNTKK 233 ++ +G +L ++ +T+ Sbjct: 76 SASSDPSAVQGADLVLFCVKSTDTQS 101 >3KYB-A nrPDB Length = 390 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 17/102 (16%), Positives = 42/102 (41%), Gaps = 15/102 (14%) Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTV 212 ++K + ++G G S + L + G +V ++ ++DH+ ++ + +E N + + Sbjct: 2 KSKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHV---YG 58 Query: 213 ALEAKGDGKLLN------------ALRIKNTKKNEETDLPVS 242 D + + R+K T + LP++ Sbjct: 59 PHIFHTDNETVWNYINKHAEMMPYVNRVKATVNGQVFSLPIN 100 >3FPZ-A nrPDB Length = 326 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 15/50 (30%), Positives = 25/50 (50%), Gaps = 4/50 (8%) Query: 4 NKVTIIGSGPAAHTAAIYLA--RAEIKPILYEG--MMANGIAAGGQLTTT 49 + V I+G+G + +AA +A R ++K + E G GGQL + Sbjct: 66 SDVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSA 115 >3NIX-A nrPDB Length = 421 Score = 38.8 bits (89), Expect = 0.003, Method: Composition-based stats. Identities = 25/169 (14%), Positives = 49/169 (28%), Gaps = 41/169 (24%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTT-TTEIENFPGFPDG 61 V +IG+GPA AA + ++ K + E G L E + GF D Sbjct: 5 KVDVLVIGAGPAGTVAASLVNKSGFKVKIVEKQKFPRFVIGESLLPRCMEHLDEAGFLDA 64 Query: 62 LTGSELMDR--------------------------------------MREQSTKFGTEII 83 + + + +++ + G ++ Sbjct: 65 VKAQGFQQKFGAKFVRGKEIADFNFSDQFSNGWNWTWQVPRGNFDKTLADEAARQGVDVE 124 Query: 84 TET-VSKVD-LSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPG 130 E V+ + + + N + + II A+G + G Sbjct: 125 YEVGVTDIKFFGTDSVTTIEDINGNKREIEARFIIDASGYGRVIPRMFG 173 >2BXR-A nrPDB Length = 527 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 14/33 (42%), Positives = 19/33 (57%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 + VIGGG S A+ LT+YG V +L +D Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDR 47 Score = 34.6 bits (78), Expect = 0.062, Method: Composition-based stats. Identities = 17/95 (17%), Positives = 33/95 (34%), Gaps = 1/95 (1%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V +IG G + +AA L + ++ E G + + G G T Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQ 74 Query: 65 SELMDRMRE-QSTKFGTEIITETVSKVDLSSKPFK 98 + ++ +E + + V V + PF+ Sbjct: 75 NRILRLSKELGIETYKVNVSERLVQYVKGKTYPFR 109 >3IHG-A nrPDB Length = 535 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 18/102 (17%), Positives = 37/102 (36%), Gaps = 3/102 (2%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAA--GGQLTTTTEIENFPGFP-D 60 V ++G+G + A++LAR ++ ++ E GQ T E+ G + Sbjct: 6 VDVLVVGAGLGGLSTAMFLARQGVRVLVVERRPGLSPYPRAAGQNPRTMELLRIGGVADE 65 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTE 102 + ++ + + + E + V S TE Sbjct: 66 VVRADDIRGTQGDFVIRLAESVRGEILRTVSESFDDMVAATE 107 Score = 33.0 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 + V+G G A FL + G +V ++ R+ L Sbjct: 7 DVLVVGAGLGGLSTAMFLARQGVRVLVVERRPGL 40 >2GAG-A nrPDB Length = 965 Score = 38.0 bits (87), Expect = 0.005, Method: Composition-based stats. Identities = 47/285 (16%), Positives = 93/285 (32%), Gaps = 27/285 (9%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTT----EIENFPG 57 VH V ++G+GPA AA +R+ + +L + AGG L T + + Sbjct: 127 VHTDVLVVGAGPAGLAAAREASRSGARVMLLD----ERAEAGGTLLDTAGEQIDGMDSSA 182 Query: 58 FPDGLTGSELMDRMR-EQSTK------FGTEIITETVSKVDLSSKPFKLWTEFNEDAEPV 110 + + +T SEL + + + + + + E + Sbjct: 183 WIEQVT-SELAEAEETTHLQRTTVFGSYDANYLI-AAQRRTVHLDGPSGPGVSRERIWHI 240 Query: 111 TTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEA 170 ++LATGA + + + A + +AV DSA E Sbjct: 241 RAKQVVLATGAHERPIVFENNDRPGIMLAGAVRSYLNRYGVRAGARIAVATTNDSAYELV 300 Query: 171 QFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRI-- 228 + L G V ++ R+S + ++++ +V ++ + D + + Sbjct: 301 RELAATGGVVAVI----DARSSISAAAAQAVADGVQVISGSVVVDTEADENGELSAIVVA 356 Query: 229 ---KNTKKNEETDLPVSGLFYAIGHTPATKIVAG-QVDTDEAGYI 269 + + L A G P + + Q D I Sbjct: 357 ELDEARELGGTQRFEADVLAVAGGFNPVVHLHSQRQGKLDWDTTI 401 >4TXK-A nrPDB Length = 615 Score = 38.0 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 K ++G+GP AA+ LA + +L E + Sbjct: 85 TKCLVVGAGPCGLRAAVELALLGARVVLVEKRIK 118 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 17/42 (40%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIM 195 N V+G G A L G++V ++ ++ ++ Sbjct: 84 NTKCLVVGAGPCGLRAAVELALLGARVVLVEKRIKFSRHNVL 125 >2BRY-A nrPDB Length = 497 Score = 38.0 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 17/34 (50%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 K ++G+GP AA+ LA + +L E + Sbjct: 93 TKCLVVGAGPCGLRAAVELALLGARVVLVEKRIK 126 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 8/42 (19%), Positives = 17/42 (40%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIM 195 N V+G G A L G++V ++ ++ ++ Sbjct: 92 NTKCLVVGAGPCGLRAAVELALLGARVVLVEKRIKFSRHNVL 133 >2VVL-G nrPDB Length = 495 Score = 38.0 bits (87), Expect = 0.006, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 21/52 (40%), Gaps = 5/52 (9%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFP 56 V +IG G TA L A K +L E G + ++ I+ +P Sbjct: 41 DVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGR-----SWSSNIDGYP 87 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 16/34 (47%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 + VIGGG + LT G K +L +D + Sbjct: 41 DVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRI 74 >1REO-A nrPDB Length = 486 Score = 37.7 bits (86), Expect = 0.006, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 33/77 (42%), Gaps = 3/77 (3%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V ++G+G + +AA L+ A + + E G G T + E++ + Sbjct: 36 VVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAG---GRVRTYRNDKEDWYANLGPMRLP 92 Query: 66 ELMDRMREQSTKFGTEI 82 E +RE KFG ++ Sbjct: 93 EKHRIVREYIRKFGLQL 109 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 K + V+G G S A L+ G +V +L + Sbjct: 34 KHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASER 67 >4MOP-A nrPDB Length = 633 Score = 37.3 bits (85), Expect = 0.008, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 30/66 (45%), Gaps = 2/66 (3%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYE-GMMANGIAAGGQLTTTTEIE-NFPGFP 59 + V I+GSGP T A L A K +++ G + +G+ G T E + N F Sbjct: 45 IKYDVVIVGSGPIGCTYARELVGAGYKVAMFDIGEIDSGLKIGAHKKNTVEYQKNIDKFV 104 Query: 60 DGLTGS 65 + + G Sbjct: 105 NVIQGQ 110 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 24/122 (19%), Positives = 38/122 (31%), Gaps = 7/122 (5%) Query: 142 CAVCDGAVPIFRNK-PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD---HLRASTIMQK 197 D VP K + ++G G C A+ L G KV M + L+ + Sbjct: 33 LPGPDKKVPGMDIKYDVVIVGSGPIGCTYARELVGAGYKVAMFDIGEIDSGLKIGAHKKN 92 Query: 198 RAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIV 257 E + I+ N + + +N L + T S F G P + Sbjct: 93 TVEYQKNIDKFVNVIQGQLMSVSVPVNTLVV---DTLSPTSWQASTFFVRNGSNPEQDPL 149 Query: 258 AG 259 Sbjct: 150 RN 151 >1NAA-A nrPDB Length = 541 Score = 36.9 bits (84), Expect = 0.010, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 18/40 (45%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGG 44 I+G+GP AA L+ A K +L E + GG Sbjct: 4 DYIIVGAGPGGIIAADRLSEAGKKVLLLERGGPSTKQTGG 43 Score = 28.4 bits (62), Expect = 4.3, Method: Composition-based stats. Identities = 9/29 (31%), Positives = 14/29 (48%) Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRK 186 ++G G A L++ G KV +L R Sbjct: 6 IIVGAGPGGIIAADRLSEAGKKVLLLERG 34 >5CQF-A nrPDB Length = 443 Score = 36.9 bits (84), Expect = 0.011, Method: Composition-based stats. Identities = 40/240 (16%), Positives = 74/240 (30%), Gaps = 48/240 (20%) Query: 2 VHNKVTIIGSGPAA--HTAAIYLARAEIKPILYEGMMANGIAAGGQ-----LTTTTEIEN 54 +H+ IG GPA A AR +P+ + A Q L T+I N Sbjct: 12 LHSDAICIGFGPAGIALACAFEDAREASQPLGDLSIGYLEAAPDTQWHRELLLAGTDI-N 70 Query: 55 FPGFPDGLTGS------ELMDRMREQSTKFGTEIITE----------------------- 85 F D +T +++Q F ++ Sbjct: 71 HHVFRDLVTPRNPRSRFSFAMYLKDQGRMFDFGLLGRPASRHEWSDYLGWVSRQVDGHTR 130 Query: 86 ---TVSKVDLSSKPFKLWTEFNEDAE-PVTTDAIILATGASAKRMHLPGEETYWQKGISA 141 V+++D + +L + T ++L++G++ + E + Sbjct: 131 FDTPVTEIDPVIRNGRLQEVRVRTPQGSFATRNLVLSSGSAPRIPQAF--EALLGPTLFH 188 Query: 142 CAVCDGAVPIFR---NKPLAVIGGGDSACEEAQFLTKY--GSKVFMLVRKDHLRASTIMQ 196 + + F K V+G G SA E L +V + R + + + Q Sbjct: 189 TSRFLTRLQAFGKQLPKRWLVLGSGQSASESVLELVSRDPAIEVHSVHRCAGFKLTQLGQ 248 >5MOG-A nrPDB Length = 497 Score = 36.9 bits (84), Expect = 0.012, Method: Composition-based stats. Identities = 17/47 (36%), Positives = 23/47 (48%), Gaps = 4/47 (8%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTE 51 +V I G+G A + A YLA A KPIL E GG++ + Sbjct: 19 QVVIAGAGLAGLSTAKYLADAGHKPILLEA----RDVLGGKIAAWKD 61 Score = 28.8 bits (63), Expect = 3.0, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 16/33 (48%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 + + G G + A++L G K +L +D L Sbjct: 20 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVL 52 >1C0L-A nrPDB Length = 363 Score = 36.9 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 14/32 (43%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVR 185 K + V+G G A L + G V +L R Sbjct: 6 QKRVVVLGSGVIGLSSALILARKGYSVHILAR 37 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 19/34 (55%), Gaps = 2/34 (5%) Query: 1 MVHN--KVTIIGSGPAAHTAAIYLARAEIKPILY 32 M+H+ +V ++GSG ++A+ LAR + Sbjct: 2 MMHSQKRVVVLGSGVIGLSSALILARKGYSVHIL 35 >3BHF-A nrPDB Length = 390 Score = 36.9 bits (84), Expect = 0.013, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMA 37 H V ++G+G A LA+ +K +L + Sbjct: 4 HFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDP 38 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 29/130 (22%), Positives = 49/130 (37%), Gaps = 19/130 (14%) Query: 2 VHNKVTIIGSGPAAHTA----AIYLARA-EIKPILYEGMMANGIAAGGQLTTTTEIENFP 56 + K ++ GP +A + A+ + L EG N G T EN+ Sbjct: 84 IFTKTGVLVFGPKGESAFVAETMEAAKEHSLTVDLLEGDEINKRWPG-----ITVPENYN 138 Query: 57 GFPDGLTGSELMDRM----REQSTKFGTEIITET-VSKVDLSSKPFKLWTEFNEDAEPVT 111 + +G + RE + G +++T T V D+S K+ T T Sbjct: 139 AIFEPNSGVLFSENCIRAYRELAEARGAKVLTHTRVEDFDISPDSVKIETANGS----YT 194 Query: 112 TDAIILATGA 121 D +I++ GA Sbjct: 195 ADKLIVSMGA 204 >3JSK-A nrPDB Length = 344 Score = 36.5 bits (83), Expect = 0.014, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 23/50 (46%), Gaps = 4/50 (8%) Query: 4 NKVTIIGSGPAAHTAAIYLA--RAEIKPILYEGM--MANGIAAGGQLTTT 49 + I+G+G +AA L+ R +++ + E G GGQL + Sbjct: 80 TDIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAWLGGQLFSA 129 >1VRQ-A nrPDB Length = 964 Score = 36.5 bits (83), Expect = 0.015, Method: Composition-based stats. Identities = 38/262 (14%), Positives = 81/262 (30%), Gaps = 16/262 (6%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG----IAAGGQLTTTTEIENFPG 57 VH V ++G+GPA AA +R+ + +L + G A+G Q+ + Sbjct: 126 VHTDVLVVGAGPAGLAAAREASRSGARVMLLDERPEAGGTLREASGEQIDGIDAAQWIDA 185 Query: 58 FPDGLTGSELMDRMREQST--KFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAI 115 + L +E ++ + + I + + E + + Sbjct: 186 VTEELAAAEETTHLQRTTVFGSYDANYIL-AAQRRTVHLDGPSGQGVSRERIWHIRAKQV 244 Query: 116 ILATGASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTK 175 +LAT A + + + + + +AV DS L Sbjct: 245 VLATAAHERPIVFENNDRPGIMLAGSVRSYLNRFGVRAGSKIAVATTNDSVYPLVSELAA 304 Query: 176 YGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRI-----KN 230 G V ++ + ++ A+ + + +L +V + D + + + Sbjct: 305 SGGVVAVIDARQNISAAAAQAV----TDGVTVLTGSVVANTEADASGELSAVLVATLDEQ 360 Query: 231 TKKNEETDLPVSGLFYAIGHTP 252 E L + G P Sbjct: 361 RNLGEAQRFEADVLAVSGGFNP 382 >5KXJ-A nrPDB Length = 557 Score = 36.5 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 41/114 (35%), Gaps = 8/114 (7%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGI---AAGGQLTTTTEIENFPGFPDG 61 V IIGSG A + A+ LA +L +G ++ G A GG E ++ + Sbjct: 10 DVLIIGSGAAGLSLALRLAEKHKVIVLSKGPVSEGSTFYAQGGIAAVFDETDSIASHVED 69 Query: 62 --LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTD 113 + G+ + DR + +F V + F + N T Sbjct: 70 TLIAGAGICDR---HAVEFVASNARTCVQWLIDQGVLFDTHVQPNGKESYHLTR 120 Score = 30.7 bits (68), Expect = 0.80, Method: Composition-based stats. Identities = 7/20 (35%), Positives = 9/20 (45%) Query: 270 KTVPGSSLTSVPGFFAAGDV 289 V T V G +A G+V Sbjct: 357 VVVDDYGRTDVDGLYAIGEV 376 >4IIN-A nrPDB Length = 271 Score = 36.5 bits (83), Expect = 0.017, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 26/65 (40%), Gaps = 1/65 (1%) Query: 152 FRNKPLAVIGGGD-SACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYN 210 F K + + G E A+ L G KV++ R + A + + EK K ++ Sbjct: 27 FTGKNVLITGASKGIGAEIAKTLASMGLKVWINYRSNAEVADALKNELEEKGYKAAVIKF 86 Query: 211 TVALE 215 A E Sbjct: 87 DAASE 91 >5XGV-A nrPDB Length = 462 Score = 36.1 bits (82), Expect = 0.018, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 17/45 (37%), Gaps = 1/45 (2%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMM-ANGIAAGGQLTTT 49 V I G GP A L A + ++ E + GG + T Sbjct: 4 VIIAGGGPVGLMLACELGLAGVDTVVLERHDAPREPSRGGAINAT 48 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 12/32 (37%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 + + GGG A L G +L R D Sbjct: 3 TVIIAGGGPVGLMLACELGLAGVDTVVLERHD 34 >4Z2R-A nrPDB Length = 592 Score = 35.7 bits (81), Expect = 0.029, Method: Composition-based stats. Identities = 11/50 (22%), Positives = 20/50 (40%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIE 53 V I+G+GPA +A LA I+ ++ + + +E Sbjct: 13 TDVLIVGAGPAGAMSATLLASLGIRSLMINRWRSTSPGPRSHIINQRTME 62 >4IV9-A nrPDB Length = 557 Score = 35.7 bits (81), Expect = 0.030, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 27/77 (35%), Gaps = 2/77 (2%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIK-PILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 +V I+G+G + AA L RA +K +LYE G Q+ T Sbjct: 40 RVAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRF 99 Query: 64 GSELMDRMREQSTKFGT 80 + KFG Sbjct: 100 PPS-ATGLFHYLKKFGI 115 Score = 33.0 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 16/35 (45%), Gaps = 1/35 (2%) Query: 156 PLAVIGGGDSACEEAQFLTKYG-SKVFMLVRKDHL 189 +A++G G S A L + G V + +D + Sbjct: 40 RVAIVGAGISGLVAATELLRAGVKDVVLYESRDRI 74 >5PGZ-A nrPDB Length = 276 Score = 35.3 bits (80), Expect = 0.033, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 17/40 (42%), Gaps = 1/40 (2%) Query: 150 PIFRNKPLAVIGGGD-SACEEAQFLTKYGSKVFMLVRKDH 188 + + K + V G E A L+K G+ V + R + Sbjct: 14 EMLQGKKVIVTGASKGIGREMAYHLSKMGAHVVLTARSEE 53 >5NA1-A nrPDB Length = 408 Score = 35.3 bits (80), Expect = 0.036, Method: Composition-based stats. Identities = 52/317 (16%), Positives = 100/317 (31%), Gaps = 52/317 (16%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV ++G+G A L +A I E + N + T E G L Sbjct: 13 KVLVLGAGYAGLQTVTKLQKA-ISTEEAEITLINKNEYHYEATWLH--EASAG---TLNY 66 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 +++ + K + V+K+D +K + + D +++A G ++ Sbjct: 67 EDVLYPVESVLKKDKVNFVQAEVTKIDRDAKKVET------NQGIYDFDILVVALGFVSE 120 Query: 125 RMHLPG--------EETYWQKGISAC---AVCDGAVPIFRNK---PLAVIGGGDSACEEA 170 + G E + +S + A ++ + V G G + E Sbjct: 121 TFGIEGMKDHAFQIENVITARELSRHIEDKFANYAASKEKDDNDLSILVGGAGFTGVEFL 180 Query: 171 QFLT--------KYGS-----KVFMLVRKDHLRA--STIMQKRA---EKNEKIEILYNTV 212 LT KYG K+ + + S + A ++ +E T Sbjct: 181 GELTDRIPELCSKYGVDQNKVKITCVEAAPKMLPMFSEELVNHAVSYLEDRGVEFKIATP 240 Query: 213 ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTV 272 + G ++ E+ L +A G +K++ + + G I T Sbjct: 241 IVACNEKGFVVE-------VDGEKQQLNAGTSVWAAGVR-GSKLMEESFEGVKRGRIVTK 292 Query: 273 PGSSLTSVPGFFAAGDV 289 ++ F GD Sbjct: 293 QDLTINGYDNIFVIGDC 309 >3S61-A nrPDB Length = 463 Score = 35.3 bits (80), Expect = 0.037, Method: Composition-based stats. Identities = 25/111 (22%), Positives = 46/111 (41%), Gaps = 10/111 (9%) Query: 71 MREQSTKFGTEIITETVSKVDLSSKPFKLWTE-FNEDAEPV--TTDAIILATGASAKRMH 127 +EQS ++G E++ + + + + L N D E + TT A++++ G + + Sbjct: 140 FQEQS-RYGEEVL--RIEPMLSAGQVEALRVISRNADGEELVRTTRALVVSPGGTPRIPQ 196 Query: 128 LPGEETYWQKGISACAVCD--GAVPIFRNKP--LAVIGGGDSACEEAQFLT 174 + + + P KP +A+IGGG SA E L Sbjct: 197 VFRALKGDGRVFHHSQYLEHMAKQPCSSGKPMKIAIIGGGQSAAEAFIDLN 247 >1RP0-A nrPDB Length = 284 Score = 35.3 bits (80), Expect = 0.038, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 24/52 (46%), Gaps = 3/52 (5%) Query: 4 NKVTIIGSGPAAHTAAIYLARA-EIKPILYEG--MMANGIAAGGQLTTTTEI 52 V ++G+G A +AA +++ ++ + E G GGQL + + Sbjct: 40 TDVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAWLGGQLFSAMIV 91 >1FOH-A nrPDB Length = 664 Score = 35.3 bits (80), Expect = 0.039, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 31/69 (44%), Gaps = 9/69 (13%) Query: 3 HNKVTIIGSGPAAHTAAIYLA-----RAEIKPILYEGMMA---NGIAAGGQLTTTTEIEN 54 + V I+G+GPA AA L+ + ++K + + NG A G Q T ++N Sbjct: 7 YCDVLIVGAGPAGLMAARVLSEYVRQKPDLKVRIIDKRSTKVYNGQADGLQCRTLESLKN 66 Query: 55 FPGFPDGLT 63 G D + Sbjct: 67 L-GLADKIL 74 >6C6P-A nrPDB Length = 458 Score = 35.0 bits (79), Expect = 0.040, Method: Composition-based stats. Identities = 16/87 (18%), Positives = 35/87 (40%), Gaps = 4/87 (4%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVA-L 214 + ++G G A L++ G KV ++ R L+ + + +L + Sbjct: 9 EVIIVGAGVLGSALAAVLSRDGRKVTVIER--DLKEPDRIVGEFLQPGGYHVLKDLGLGD 66 Query: 215 EAKG-DGKLLNALRIKNTKKNEETDLP 240 +G D +++N I + + E +P Sbjct: 67 TVEGLDAQVVNGYMIHDQESKSEVQIP 93 >3KVE-A nrPDB Length = 486 Score = 35.0 bits (79), Expect = 0.043, Method: Composition-based stats. Identities = 21/78 (26%), Positives = 33/78 (42%), Gaps = 5/78 (6%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEI-ENFPGFPDGLTG 64 V ++G+G + +AA LA A K + E AGG++ T E + + Sbjct: 36 VVVVGAGMSGLSAAYVLAGAGHKVTVLEA----SERAGGRVRTHRNSKEGWYANLGPMRI 91 Query: 65 SELMDRMREQSTKFGTEI 82 E +RE KFG + Sbjct: 92 PEKHRIVREYIRKFGLNL 109 Score = 34.2 bits (77), Expect = 0.072, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 15/34 (44%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 K + V+G G S A L G KV +L + Sbjct: 34 KHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASER 67 >2QA2-A nrPDB Length = 499 Score = 35.0 bits (79), Expect = 0.044, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMAN-GIAAG-GQLTTTTEIENFPGFPDGLT 63 V ++G+GPA A L + ++ E + G + G G T E+ + G Sbjct: 15 VIVVGAGPAGLMLAGELRLGGVDVMVLEQLPQRTGESRGLGFTARTMEVFDQRGILPAFG 74 Query: 64 GSE 66 E Sbjct: 75 PVE 77 >5TUF-A nrPDB Length = 409 Score = 34.6 bits (78), Expect = 0.053, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 21/44 (47%), Gaps = 2/44 (4%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQ 45 H K+ +IG G A A +L R P+L E + + GGQ Sbjct: 24 KHIKILVIGVGVAGPAVAYWLKRFGFSPVLIEK--SAAVRKGGQ 65 >2E5V-A nrPDB Length = 472 Score = 34.6 bits (78), Expect = 0.053, Method: Composition-based stats. Identities = 13/37 (35%), Positives = 17/37 (45%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAA 42 + IIGSG A +A + L RA K L + G Sbjct: 2 IYIIGSGIAGLSAGVALRRAGKKVTLISKRIDGGSTP 38 Score = 27.3 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 15/30 (50%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRK 186 + +IG G + L + G KV ++ ++ Sbjct: 2 IYIIGSGIAGLSAGVALRRAGKKVTLISKR 31 Score = 27.3 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 53/283 (18%), Positives = 97/283 (34%), Gaps = 57/283 (20%) Query: 63 TGSELMDRMREQSTKFGTEIITETVSKVDL-SSKPFKLWTEFNEDAEPVTTDAIILATGA 121 TG E+ + + + + + G II + + ++ + K TE E V D ++LATG Sbjct: 117 TGREIFNFLLKLAREEGIPIIEDRLVEIRVKDGKVTGFVTEKRGLVEDV--DKLVLATGG 174 Query: 122 SAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQF---LTKYGS 178 Y + + DG F+ + + E QF +T Sbjct: 175 Y--------SYLYEYSSTQSTNIGDGMAIAFKAGTIL------ADMEFVQFHPTVTSLDG 220 Query: 179 KVFMLVRKDHLRAS------------TIMQKRAEKNEKIEILYNTVALEAKGDGKLLNAL 226 +VF+L + LR + + +IL + +E K+ + Sbjct: 221 EVFLLT--ETLRGEGAQIINENGERFLFNYDKRGELAPRDILSRAIYIEMLKGHKV--FI 276 Query: 227 RIKNTKKNEETDLPVSGLFYAIGHT--------PATKIVAGQVDTDEAGYIKTVPGSSLT 278 + + E V+ GH PA V G + + G + Sbjct: 277 DLSKIEDFERKFPVVAKYLARHGHNYKVKIPIFPAAHFVDGGIRVNIRG---------ES 327 Query: 279 SVPGFFAAGDVQDSKY----RQAITSAGSGCMAALDAEKYLTS 317 ++ +A G+V DS R A S G + ++ +Y+ S Sbjct: 328 NIVNLYAIGEVSDSGLHGANRLASNSLLEGLVFGINLPRYVDS 370 >2DKH-A nrPDB Length = 639 Score = 34.6 bits (78), Expect = 0.058, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 19/43 (44%), Gaps = 3/43 (6%) Query: 4 NKVTIIGSGPAAHT-AAIYLARAEIKPILYEGMMANGIAAGGQ 45 V I+G GPA T AA A +I+ + E G GQ Sbjct: 33 VDVLIVGCGPAGLTLAAQLAAFPDIRTCIVE--QKEGPMELGQ 73 >5KOX-A nrPDB Length = 476 Score = 34.6 bits (78), Expect = 0.065, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 23/75 (30%), Gaps = 7/75 (9%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 V I G GP A L ++ ++ E + + IE + Sbjct: 5 IDVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHSRSRGLHARSIE-------VMD 57 Query: 64 GSELMDRMREQSTKF 78 L++R +F Sbjct: 58 QRGLLERFLAHGEQF 72 >5Z70-A nrPDB Length = 605 Score = 34.6 bits (78), Expect = 0.067, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 2/48 (4%) Query: 8 IIGSGPAAHTAAIYLARAE-IKPILYEGMMANGIAAGGQLTTTTEIEN 54 IIGSG A +A YL R +K + A G GG L + E+ Sbjct: 9 IIGSGIAGLASAFYLIRDGRMKGQDITILDAVG-TPGGSLDGSGNAED 55 >4EIQ-A nrPDB Length = 549 Score = 34.2 bits (77), Expect = 0.073, Method: Composition-based stats. Identities = 8/41 (19%), Positives = 16/41 (39%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAA 42 + V I+G GP A+ LA ++ ++ + Sbjct: 25 IETDVLILGGGPVGMALALDLAHRQVGHLVVDAGDGTITHP 65 >2CDC-A nrPDB Length = 366 Score = 34.2 bits (77), Expect = 0.079, Method: Composition-based stats. Identities = 9/48 (18%), Positives = 19/48 (39%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKN 202 + + V+G G YG +V+M R++ + + + N Sbjct: 182 RKVLVVGTGPIGVLFTLLFRTYGLEVWMANRREPTEVEQTVIEETKTN 229 >1O5W-A nrPDB Length = 534 Score = 34.2 bits (77), Expect = 0.080, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 21/43 (48%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR 198 + VIGGG S A+ L++Y V +L +D + T + Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRN 65 Score = 30.7 bits (68), Expect = 0.81, Method: Composition-based stats. Identities = 18/95 (18%), Positives = 34/95 (35%), Gaps = 1/95 (1%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 V +IG G + AA L+ +I ++ E G + + G G T Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQ 82 Query: 65 SELMDRMRE-QSTKFGTEIITETVSKVDLSSKPFK 98 + ++ +E + + V V + PF+ Sbjct: 83 NRILRLSKELGIETYKVNVNERLVQYVKGKTYPFR 117 >4Z25-A nrPDB Length = 652 Score = 34.2 bits (77), Expect = 0.088, Method: Composition-based stats. Identities = 14/39 (35%), Positives = 20/39 (51%), Gaps = 1/39 (2%) Query: 5 KVTIIGSGPAAHTAAIYLAR-AEIKPILYEGMMANGIAA 42 + IIG+G A A YLAR + +K IL E ++ Sbjct: 8 DIVIIGAGAAGSLLAHYLARFSNMKIILLEAGHSHFNDP 46 >4K2X-A nrPDB Length = 523 Score = 33.8 bits (76), Expect = 0.100, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 25/66 (37%), Gaps = 2/66 (3%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGM--MANGIAAGGQLTTTTEIENFPGFP 59 + V I G+GP A L A + ++ E + + A G T E+ + G Sbjct: 21 MRYDVVIAGAGPTGLMLACELRLAGARTLVLERLAEPVDFSKALGVHARTVELLDMRGLG 80 Query: 60 DGLTGS 65 +G Sbjct: 81 EGFQAE 86 >2GMH-A nrPDB Length = 584 Score = 33.8 bits (76), Expect = 0.10, Method: Composition-based stats. Identities = 8/16 (50%), Positives = 11/16 (68%) Query: 4 NKVTIIGSGPAAHTAA 19 V I+G+GPA +AA Sbjct: 36 ADVVIVGAGPAGLSAA 51 >4CJX-A nrPDB Length = 319 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 24/64 (37%), Gaps = 8/64 (12%) Query: 154 NKPLAVIGGGDSA-CEEAQFLTKYGSKVFMLVRKDHL-------RASTIMQKRAEKNEKI 205 K + V+G GD A A L + V ++ L RAS I+ A + + Sbjct: 184 GKRVVVLGRGDIAGLPVATLLANEDATVTVVHSATPLCDIADIVRASDIVVSAAGQPGLV 243 Query: 206 EILY 209 + Sbjct: 244 RGEW 247 >3TL2-A nrPDB Length = 315 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 26/64 (40%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 + KV++IG+G T A LA+ E+ ++ + G+ E GF Sbjct: 6 IKRKKVSVIGAGFTGATTAFLLAQKELADVVLVDIPQLENPTKGKALDMLEASPVQGFDA 65 Query: 61 GLTG 64 + G Sbjct: 66 NIIG 69 >2IPC-A nrPDB Length = 997 Score = 33.8 bits (76), Expect = 0.11, Method: Composition-based stats. Identities = 19/101 (18%), Positives = 38/101 (37%), Gaps = 3/101 (2%) Query: 92 LSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVPI 151 + TE E E D +++ T R P +KG V + A Sbjct: 381 RAGMTGTAKTEEKEFQEIYGMDVVVVPTNRPVIRKDFPDVVYRTEKGKFYAVVEEIAEKY 440 Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAS 192 R +P+ V G + E+++ L++ + + + + +R Sbjct: 441 ERGQPVLV---GTISIEKSERLSQMLKEPRLYLPRLEMRLE 478 >3I6D-A nrPDB Length = 470 Score = 33.4 bits (75), Expect = 0.12, Method: Composition-based stats. Identities = 17/97 (17%), Positives = 38/97 (39%), Gaps = 7/97 (7%) Query: 6 VTIIGSGPAAHTAAIYLAR--AEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLT 63 V IIG G AA Y+ + E L ++ GG++ T + G+ Sbjct: 8 VVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKK----DGYIIERG 63 Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLW 100 ++R ++ + + ++ E + + + + + L Sbjct: 64 PDSFLER-KKSAPQLVKDLGLEHLLVNNATGQSYVLV 99 >6DLL-A nrPDB Length = 398 Score = 33.4 bits (75), Expect = 0.14, Method: Composition-based stats. Identities = 16/88 (18%), Positives = 32/88 (36%), Gaps = 1/88 (1%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEA 216 +A+IG G S Q L K G ++ R+ ++ + +++L E Sbjct: 8 VAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRAGVLEQGTVDLLREAGVAE- 66 Query: 217 KGDGKLLNALRIKNTKKNEETDLPVSGL 244 + D + L ++ L + L Sbjct: 67 RMDREGLVHEGVELLVGGRRQRLDLKAL 94 Score = 32.3 bits (72), Expect = 0.27, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 17/32 (53%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYE 33 + +V IIG+GP+ L +A I I+ E Sbjct: 4 MKTQVAIIGAGPSGLLLGQLLHKAGIDNIIVE 35 >1SEZ-A nrPDB Length = 504 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 17/75 (22%), Positives = 25/75 (33%), Gaps = 12/75 (16%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVR------------KDHLRASTIMQKRAEKN 202 K +AVIG G S A L +G V + +D L E Sbjct: 14 KRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIWDEGANTMTESE 73 Query: 203 EKIEILYNTVALEAK 217 + L +++ L K Sbjct: 74 GDVTFLIDSLGLREK 88 Score = 31.5 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 20/42 (47%), Gaps = 4/42 (9%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQL 46 +V +IG+G + AA L + ++E AGG+L Sbjct: 15 RVAVIGAGVSGLAAAYKLKIHGLNVTVFEA----EGKAGGKL 52 Score = 31.1 bits (69), Expect = 0.69, Method: Composition-based stats. Identities = 13/45 (28%), Positives = 19/45 (42%), Gaps = 2/45 (4%) Query: 274 GSSLTSVPGFFAAGDVQDSKYRQAITSAGSGCMAALDAEKYLTSL 318 ++PG F AG+ + + SGC AA YL S+ Sbjct: 454 DKMEKNLPGLFYAGNHRGGL--SVGKALSSGCNAADLVISYLESV 496 >1DOD-A nrPDB Length = 394 Score = 33.0 bits (74), Expect = 0.16, Method: Composition-based stats. Identities = 10/32 (31%), Positives = 17/32 (53%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYE 33 + +V IIG+GP+ L +A I ++ E Sbjct: 1 MKTQVAIIGAGPSGLLLGQLLHKAGIDNVILE 32 Score = 31.9 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 27/73 (36%), Gaps = 1/73 (1%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEA 216 +A+IG G S Q L K G +L R+ ++ + +++L Sbjct: 5 VAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRAGVLEQGMVDLLREAGVDRR 64 Query: 217 KG-DGKLLNALRI 228 DG + + I Sbjct: 65 MARDGLVHEGVEI 77 >6CR0-A nrPDB Length = 440 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 17/40 (42%) Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK 197 V+G G S A+ L+ G V ++ + L T + Sbjct: 12 IVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVVN 51 Score = 30.7 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 13/60 (21%), Positives = 22/60 (36%), Gaps = 8/60 (13%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 ++G+G + AA L+ ++ E G T + NF G P + G Sbjct: 10 DAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGR--------THVVNFLGRPVEIGG 61 >6J0Z-C nrPDB Length = 491 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 10/53 (18%), Positives = 21/53 (39%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFP 56 + V ++G+GP A L A + ++ + + + + IE F Sbjct: 6 SDVVVVGAGPTGLMLAGELRLAGVSVVVLDKLAEPIKESRALGFSARTIEEFA 58 Score = 30.7 bits (68), Expect = 0.86, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 21/49 (42%), Gaps = 4/49 (8%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAE 200 F + + V+G G + A L G V +L D L A I + RA Sbjct: 3 FYDSDVVVVGAGPTGLMLAGELRLAGVSVVVL---DKL-AEPIKESRAL 47 >1KNR-A nrPDB Length = 540 Score = 33.0 bits (74), Expect = 0.17, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 41/114 (35%), Gaps = 8/114 (7%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGI---AAGGQLTTTTEIENFPGFPDG 61 V IIGSG A + A+ LA +L +G + G A GG E ++ + Sbjct: 10 DVLIIGSGAAGLSLALRLADQHQVIVLSKGPVTEGSTFYAQGGIAAVFDETDSIDSHVED 69 Query: 62 --LTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTD 113 + G+ + DR + +F V + F + N + T Sbjct: 70 TLIAGAGICDR---HAVEFVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTR 120 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 7/18 (38%), Positives = 9/18 (50%) Query: 272 VPGSSLTSVPGFFAAGDV 289 V T V G +A G+V Sbjct: 359 VDDHGRTDVEGLYAIGEV 376 >5XW0-A nrPDB Length = 460 Score = 33.0 bits (74), Expect = 0.18, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 32/90 (35%), Gaps = 7/90 (7%) Query: 133 TYWQKGISAC-----AVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 G+ A F+ K +A+ G G+ A A + + G V L D Sbjct: 195 EATGYGVVYYVEHMIAHATNGQESFKGKRVAISGSGNVAQYAALKVIELGGSVVSL--SD 252 Query: 188 HLRASTIMQKRAEKNEKIEILYNTVALEAK 217 + I + + E+IE++ T + Sbjct: 253 SQGSLIINGEGSFTPEEIELIAQTKVERKQ 282 >6BRD-A nrPDB Length = 476 Score = 33.0 bits (74), Expect = 0.19, Method: Composition-based stats. Identities = 10/49 (20%), Positives = 17/49 (34%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIE 53 V ++G GP A L ++ ++ E + Q IE Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEPTRQSRAQGLHVRSIE 51 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 17/33 (51%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 + V+GGG + A L +G +V +L ++ Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETE 35 >4Z44-A nrPDB Length = 554 Score = 32.6 bits (73), Expect = 0.21, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 23/60 (38%), Gaps = 5/60 (8%) Query: 6 VTIIGSGPAAHTAAIYLARA---EIKPILYEGMMANGIAAGGQLTTT--TEIENFPGFPD 60 + I+G G A AA YL RA + L E I G + +F G P+ Sbjct: 24 IVIVGGGTAGWMAASYLVRALQQQANITLIESAAIPRIGVGEATIPSLQKVFFDFLGIPE 83 >1FW8-A nrPDB Length = 416 Score = 32.6 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 15/117 (12%) Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTT----------- 112 G+E++ ++ E++ G E++ V + + T+ D E + Sbjct: 189 GAEIVPKLMEKAKAKGVEVVL-PVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPES 247 Query: 113 DAIILATGASAKRMHL---PGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSA 166 + AT A AK + PG + + A+ D V +IGGGD+A Sbjct: 248 RKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTA 304 >1QPG-A nrPDB Length = 415 Score = 32.6 bits (73), Expect = 0.22, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 45/117 (38%), Gaps = 15/117 (12%) Query: 64 GSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTT----------- 112 G+E++ ++ E++ G E++ V + + T+ D E + Sbjct: 259 GAEIVPKLMEKAKAKGVEVVL-PVDFIIADAFSADANTKTVTDKEGIPAGWQGLDNGPES 317 Query: 113 DAIILATGASAKRMHL---PGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSA 166 + AT A AK + PG + + A+ D V +IGGGD+A Sbjct: 318 RKLFAATVAKAKTIVWNGPPGVFEFEKFAAGTKALLDEVVKSSAAGNTVIIGGGDTA 374 >4X4J-A nrPDB Length = 507 Score = 32.6 bits (73), Expect = 0.23, Method: Composition-based stats. Identities = 18/57 (31%), Positives = 25/57 (43%), Gaps = 2/57 (3%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMAN-GIAAG-GQLTTTTEIENFPGF 58 V I G+GPA A L A I ++ E + A G + G G T E+ + G Sbjct: 23 APVVIAGAGPAGLMLAGELRLAGIGVVVLERLPARTGESRGLGFTARTMEVFDQRGL 79 >3RP7-A nrPDB Length = 407 Score = 32.6 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 19/38 (50%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGI 40 H K +IG+G +AA+ L ++ I +YE + Sbjct: 23 HMKAIVIGAGIGGLSAAVALKQSGIDCDVYEAVKEIKP 60 >5X68-A nrPDB Length = 391 Score = 32.6 bits (73), Expect = 0.24, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 25/47 (53%) Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRA 199 + K +AVIGGG +A FL K ++ + ++ R +T + R+ Sbjct: 13 QRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFTRGRS 59 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 10/34 (29%), Positives = 16/34 (47%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEG 34 + KV +IG G A +LA+ + +YE Sbjct: 12 IQRKKVAVIGGGLVGSLQACFLAKRNFQIDVYEA 45 >2VOU-A nrPDB Length = 397 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 22/51 (43%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENF 55 ++ ++G + TAA+ L A + +YE G + E+ ++ Sbjct: 7 RIAVVGGSISGLTAALMLRDAGVDVDVYERSPQPLSGFGTGIVVQPELVHY 57 Score = 31.1 bits (69), Expect = 0.70, Method: Composition-based stats. Identities = 10/33 (30%), Positives = 13/33 (39%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 +AV+GG S A L G V + R Sbjct: 7 RIAVVGGSISGLTAALMLRDAGVDVDVYERSPQ 39 >3HN2-A nrPDB Length = 312 Score = 32.6 bits (73), Expect = 0.25, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 15/32 (46%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 +A++G G L + G V L+R+D Sbjct: 4 RIAIVGAGALGLYYGALLQRSGEDVHFLLRRD 35 >3K96-A nrPDB Length = 356 Score = 32.6 bits (73), Expect = 0.26, Method: Composition-based stats. Identities = 18/64 (28%), Positives = 28/64 (43%), Gaps = 5/64 (7%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPIL--YEGMMANGIAAGGQLTTTTEIENFPGFPD 60 + + I+G+G A+ LAR K L YE + + A G + N+P FP+ Sbjct: 29 KHPIAILGAGSWGTALALVLARKGQKVRLWSYESDHVDEMQAEGV--NNRYLPNYP-FPE 85 Query: 61 GLTG 64 L Sbjct: 86 TLKA 89 Score = 27.3 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 20/45 (44%), Gaps = 1/45 (2%) Query: 138 GISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 G A+ F++ P+A++G G A L + G KV + Sbjct: 14 GTENLYFQSNAMEPFKH-PIAILGAGSWGTALALVLARKGQKVRL 57 >5XMJ-A nrPDB Length = 627 Score = 32.3 bits (72), Expect = 0.26, Method: Composition-based stats. Identities = 15/75 (20%), Positives = 25/75 (33%), Gaps = 12/75 (16%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMAN-----------GIAAGGQLTTTTE 51 H V IG A A+ + A +K I+ + A G + + Sbjct: 5 HTDVLCIGGALAGERVAVEASMAGLKTIMLSLVPPRRSHSSAAQGGMQAALGNAIMGDGD 64 Query: 52 IENFPGFPDGLTGSE 66 + F D + GS+ Sbjct: 65 SPDVH-FADTVKGSD 78 >6FEA-B nrPDB Length = 475 Score = 32.3 bits (72), Expect = 0.28, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 42/96 (43%), Gaps = 6/96 (6%) Query: 127 HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRK 186 +P E ++GI+ A+ D A F NK +A+ G D AQF + + +L+ Sbjct: 300 EIP-ESLVRERGIALDALADLAHMFFANKKVAIFGHPDLVLGLAQFCMEVELEPVLLLIG 358 Query: 187 DH-----LRASTIMQKRAEKNEKIEILYNTVALEAK 217 D + I + + + IEI++N E + Sbjct: 359 DDQGNKYKKDPRIEELKNTAHFDIEIVHNADLWELE 394 >4UIR-A nrPDB Length = 646 Score = 32.3 bits (72), Expect = 0.29, Method: Composition-based stats. Identities = 15/43 (34%), Positives = 19/43 (44%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQL 46 +K+ IIGSG A +AA Y R P + GG L Sbjct: 63 SKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSL 105 >3BI4-A nrPDB Length = 516 Score = 31.9 bits (71), Expect = 0.35, Method: Composition-based stats. Identities = 17/48 (35%), Positives = 22/48 (45%), Gaps = 3/48 (6%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTT 50 KV IIG+G A AA L + I+ L + GG+L T T Sbjct: 8 KKKVIIIGAGIAGLKAASTLHQNGIQDCLV---LEARDRVGGRLQTVT 52 >3G5Q-A nrPDB Length = 443 Score = 31.9 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 13/75 (17%), Positives = 28/75 (37%), Gaps = 4/75 (5%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVAL 214 + + V+G G + E A L + G V + + R + + N++ Sbjct: 2 ERVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPKRMTPAHGTDRFAEI----VCSNSLGG 57 Query: 215 EAKGDGKLLNALRIK 229 E + + K L ++ Sbjct: 58 EGETNAKGLLQAEMR 72 Score = 28.8 bits (63), Expect = 3.7, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 18/40 (45%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGG 44 +V ++G+G A AA L R + L+E A G Sbjct: 3 RVNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPKRMTPAHG 42 >5EZ7-A nrPDB Length = 392 Score = 31.9 bits (71), Expect = 0.43, Method: Composition-based stats. Identities = 12/42 (28%), Positives = 16/42 (38%), Gaps = 4/42 (9%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQ 45 + I+G G A L RA +L E + GGQ Sbjct: 8 TDILIVGGGIAGLWLNARLRRAGYATVLVE----SASLGGGQ 45 >1QP8-A nrPDB Length = 303 Score = 31.5 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 10/43 (23%), Positives = 20/43 (46%) Query: 146 DGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 D +P+ + + +AV+G G+ + L G++V R Sbjct: 116 DVEIPLIQGEKVAVLGLGEIGTRVGKILAALGAQVRGFSRTPK 158 >5TUM-A nrPDB Length = 410 Score = 31.5 bits (70), Expect = 0.52, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 2 VHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQ 45 + K+ +IG+G A +L R P+L E I GGQ Sbjct: 24 KNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKY--ASIRKGGQ 65 >5Y77-A nrPDB Length = 473 Score = 31.5 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 19/117 (16%), Positives = 41/117 (35%), Gaps = 8/117 (6%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR----AEKNEKIEILYN 210 + + +IG G + A+ L + G +V + R+ R T + R A L Sbjct: 9 RQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSINLALAERGAHALRL 68 Query: 211 TVAL-EAKGDGKLLNA--LRIKNTKKN-EETDLPVSGLFYAIGHTPATKIVAGQVDT 263 E + ++ + + T N + S + ++I +I+ + Sbjct: 69 AGLEREVLAEAVMMRGRMVHVPGTPPNLQPYGRDDSEVIWSINRDRLNRILLDGAEA 125 Score = 31.1 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 15/40 (37%), Positives = 19/40 (47%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGG 44 +VTIIG+G A A LAR + L+E I G Sbjct: 10 QVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGA 49 >3HDH-A nrPDB Length = 302 Score = 31.5 bits (70), Expect = 0.53, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA--STIMQKRAEKNEKIEILYNTV 212 K + VIGGG AQ G V ++ + + + A +++ K K + N Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPK 75 Query: 213 ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFY 246 A GD + L +T + + + + L Sbjct: 76 A----GDEFVEKTLSSISTSTDAASVVHSTDLVV 105 >5ZBC-A nrPDB Length = 451 Score = 31.1 bits (69), Expect = 0.57, Method: Composition-based stats. Identities = 10/51 (19%), Positives = 22/51 (43%), Gaps = 5/51 (9%) Query: 1 MVHN-KVTIIGSGPAAHTAAIYL----ARAEIKPILYEGMMANGIAAGGQL 46 M H+ + I+G+G + T A +L A + +++ G ++ Sbjct: 21 MKHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKM 71 >3LK7-A nrPDB Length = 451 Score = 31.1 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 16/69 (23%), Positives = 28/69 (40%), Gaps = 3/69 (4%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT 211 F NK + V+G S A+ L K G+ V + + Q E+ I+++ + Sbjct: 7 FENKKVLVLGLARSGEAAARLLAKLGAIVTVND-GKPFDENPTAQSLLEE--GIKVVCGS 63 Query: 212 VALEAKGDG 220 LE + Sbjct: 64 HPLELLDED 72 >3UKH-A nrPDB Length = 519 Score = 31.1 bits (69), Expect = 0.60, Method: Composition-based stats. Identities = 7/18 (38%), Positives = 10/18 (55%) Query: 2 VHNKVTIIGSGPAAHTAA 19 + V +IG+GP AA Sbjct: 5 ISVDVLVIGAGPTGLGAA 22 >5X6R-A nrPDB Length = 420 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 16/74 (21%), Positives = 26/74 (35%), Gaps = 9/74 (12%) Query: 137 KGISACAVCDGAVP------IFRN---KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKD 187 +G D +P F+ + +A+IG G C A +K G V + + Sbjct: 2 RGSHHHHHHDYDIPTTENLYYFQGSMSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQ 61 Query: 188 HLRASTIMQKRAEK 201 R T K + Sbjct: 62 DPRLDTTKNKNLKS 75 >4EJ6-A nrPDB Length = 370 Score = 31.1 bits (69), Expect = 0.61, Method: Composition-based stats. Identities = 19/129 (14%), Positives = 35/129 (27%), Gaps = 18/129 (13%) Query: 142 CAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEK 201 C I +A++GGG L + ++ L ++R + Sbjct: 171 CLHGVDLSGIKAGSTVAILGGGVIGL-LTVQLARLAGATTVI-----LSTRQATKRRLAE 224 Query: 202 NEK------------IEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIG 249 +E + V L G ++ + T K G +G Sbjct: 225 EVGATATVDPSAGDVVEAIAGPVGLVPGGVDVVIECAGVAETVKQSTRLAKAGGTVVILG 284 Query: 250 HTPATKIVA 258 P + V Sbjct: 285 VLPQGEKVE 293 >3DFZ-A nrPDB Length = 223 Score = 31.1 bits (69), Expect = 0.62, Method: Composition-based stats. Identities = 21/113 (18%), Positives = 39/113 (34%), Gaps = 26/113 (23%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT 211 + + + V+GGG + R+ ++ ++ I ++ T Sbjct: 29 LKGRSVLVVGGG-----------------TIATRR--------IKGFLQEGAAITVVAPT 63 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTD 264 V+ E + + LR+K K EE L V + A K V + D Sbjct: 64 VSAEIN-EWEAKGQLRVKRKKVGEEDLLNVFFIVVATNDQAVNKFVKQHIKND 115 >4ZCC-A nrPDB Length = 336 Score = 31.1 bits (69), Expect = 0.64, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG 39 + IIG+G A +AA L A + L++ +G Sbjct: 3 VPIAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSG 38 >1KSU-A nrPDB Length = 571 Score = 31.1 bits (69), Expect = 0.67, Method: Composition-based stats. Identities = 19/86 (22%), Positives = 31/86 (36%), Gaps = 11/86 (12%) Query: 204 KIEILYNTVALEAKGDGKL-LNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVD 262 I++ NT +E D K + + +K K + + A G ++D Sbjct: 269 NIDLRMNTRGIEVLKDDKGTVKGILVKGMYKG-YYWVKADAVILATGGFAKNNERVAKLD 327 Query: 263 TDEAGYIKTVPGSSLTSVPGFFAAGD 288 G+I T+ PG A GD Sbjct: 328 PSLKGFIS-------TNQPG--AVGD 344 Score = 28.4 bits (62), Expect = 4.2, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 4/65 (6%) Query: 64 GSELMDRMREQSTKFGTEIITET----VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILAT 119 G+ ++ + + + K ++ T V K D + L + V DA+ILAT Sbjct: 254 GAHVVQVLYDNAVKRNIDLRMNTRGIEVLKDDKGTVKGILVKGMYKGYYWVKADAVILAT 313 Query: 120 GASAK 124 G AK Sbjct: 314 GGFAK 318 >4IA5-A nrPDB Length = 591 Score = 31.1 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 22/41 (53%), Gaps = 4/41 (9%) Query: 8 IIGSGPAAHTAAIYLAR-AEIK---PILYEGMMANGIAAGG 44 IIGSG A + A++L R A++K + E + G + G Sbjct: 27 IIGSGLAGLSTAVFLVRDAQMKGENIHILEELPVAGGSLDG 67 >1QO8-A nrPDB Length = 566 Score = 31.1 bits (69), Expect = 0.68, Method: Composition-based stats. Identities = 19/77 (24%), Positives = 34/77 (44%), Gaps = 6/77 (7%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG----IAAGGQLTTTTEIENFPGFP 59 +V ++G+G A A++ +A IL + +G I+AGG T+ + G Sbjct: 122 TQVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSGGNSMISAGGMNAVGTKQQTAHGVE 181 Query: 60 DGLTG--SELMDRMREQ 74 D + + M R+Q Sbjct: 182 DKVEWFIEDAMKGGRQQ 198 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 27/63 (42%), Gaps = 4/63 (6%) Query: 63 TGSELMDRMREQSTKFGTEIITET----VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILA 118 +G E++D +R+ + + G + + + D S + + + +++LA Sbjct: 248 SGPEIIDTLRKAAKEQGIDTRLNSRVVKLVVNDDHSVVGAVVHGKHTGYYMIGAKSVVLA 307 Query: 119 TGA 121 TG Sbjct: 308 TGG 310 >3KKJ-A nrPDB Length = 336 Score = 31.1 bits (69), Expect = 0.73, Method: Composition-based stats. Identities = 11/36 (30%), Positives = 18/36 (50%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANG 39 + IIG+G A +AA L A + L++ +G Sbjct: 3 VPIAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSG 38 >4K22-A nrPDB Length = 365 Score = 30.7 bits (68), Expect = 0.82, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRK 186 +A++GGG A L G +V +L ++ Sbjct: 5 DVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 8/33 (24%), Positives = 13/33 (39%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYE 33 M V I+G G A L + ++ + E Sbjct: 1 MQSVDVAIVGGGMVGLAVACGLQGSGLRVAVLE 33 >1ZFN-A nrPDB Length = 253 Score = 30.7 bits (68), Expect = 0.84, Method: Composition-based stats. Identities = 11/32 (34%), Positives = 19/32 (59%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILY 32 ++ ++V IIG G AA+YLA A + ++ Sbjct: 28 LLDSQVLIIGLGGLGTPAALYLAGAGVGTLVL 59 >3H9U-A nrPDB Length = 436 Score = 30.7 bits (68), Expect = 0.89, Method: Composition-based stats. Identities = 21/130 (16%), Positives = 40/130 (30%), Gaps = 14/130 (10%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVA 213 K V G GD A L +G++V + D + A E ++L Sbjct: 211 GKTACVCGYGDVGKGCAAALRGFGARVVVTE-VDPINA------LQAAMEGYQVLLVEDV 263 Query: 214 LEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYA-IGHTPATKIVAGQVDTDEAGYIKT- 271 +E + + +E IGH T+I + + ++ Sbjct: 264 VEEA--HIFVTTTGNDDIITSEHFPRMRDDAIVCNIGHF-DTEIQVAWLKANAKERVEVK 320 Query: 272 --VPGSSLTS 279 V ++ + Sbjct: 321 PQVDRYTMAN 330 >1F14-A nrPDB Length = 310 Score = 30.7 bits (68), Expect = 0.90, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 35/94 (37%), Gaps = 6/94 (6%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA--STIMQKRAEKNEKIEILYNTV 212 K + VIGGG AQ G V ++ + + + A +++ K K + N Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDILAKSKKGIEESLRKVAKKKFAENPK 75 Query: 213 ALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFY 246 A GD + L T + + + + L Sbjct: 76 A----GDECVEKTLSTIATSTDAASVVHSTDLVV 105 >6ETZ-A nrPDB Length = 989 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 16/52 (30%), Positives = 23/52 (44%), Gaps = 2/52 (3%) Query: 7 TIIGSG--PAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFP 56 +IG G PA + AA+ R + +L E + A G GG E +P Sbjct: 468 ALIGQGIEPALNDAALDARRRAMPFVLCEYVHAMGNGPGGMSEYQALFEKYP 519 >3IHM-A nrPDB Length = 430 Score = 30.3 bits (67), Expect = 1.2, Method: Composition-based stats. Identities = 8/54 (14%), Positives = 20/54 (37%), Gaps = 2/54 (3%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRK--DHLRASTIMQKRAEKNEKIE 206 K + ++G G + FL ++ V + + D ++ A ++ Sbjct: 23 KRIGIVGAGTAGLHLGLFLRQHDVDVTVYTDRKPDEYSGLRLLNTVAHNAVTVQ 76 >2VHY-A nrPDB Length = 377 Score = 30.0 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 19/45 (42%), Gaps = 1/45 (2%) Query: 147 GAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLV-RKDHLR 190 G VP + VIG G + A+ G+ V +L D LR Sbjct: 161 GGVPGVEPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLR 205 Score = 29.2 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 17/49 (34%), Gaps = 4/49 (8%) Query: 4 NKVTIIGSGPAAHTAAIYLARAEIKPIL----YEGMMANGIAAGGQLTT 48 V +IG+G A + AA + + + G++ T Sbjct: 169 ADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHT 217 >2BS2-A nrPDB Length = 660 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 18/46 (39%), Gaps = 4/46 (8%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMM----ANGIAAGG 44 + +IG G A AA+ + + I+ + + A GG Sbjct: 5 YCDSLVIGGGLAGLRAAVATQQKGLSTIVLSLIPVKRSHSAAAQGG 50 >6ACQ-A nrPDB Length = 302 Score = 30.0 bits (66), Expect = 1.4, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 22/64 (34%), Gaps = 2/64 (3%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL--RASTIMQKRAEKNEKIEILYNTV 212 K + VIG G AQ G +V + KD R + K K K + Sbjct: 22 KKVCVIGAGTMGSGIAQAFAAKGFEVVLRDIKDEFVDRGLDFINKNLSKLVKKGKIEEAT 81 Query: 213 ALEA 216 +E Sbjct: 82 KVEI 85 >6GAQ-A nrPDB Length = 154 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 20/46 (43%), Gaps = 6/46 (13%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQK 197 K +AV G GD+A E + V + + R + ++Q+ Sbjct: 87 LAGKKVAVFGSGDTAYEL------FCEAVTIFEERLVERGAELVQE 126 >3K5P-A nrPDB Length = 416 Score = 30.0 bits (66), Expect = 1.5, Method: Composition-based stats. Identities = 18/107 (16%), Positives = 38/107 (35%), Gaps = 13/107 (12%) Query: 137 KGISACAVCDGAVPI----FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL--- 189 + +SA A I R K L ++G G+ + G V D L Sbjct: 135 RSVSAHAGGWEKTAIGSREVRGKTLGIVGYGNIGSQVGNLAESLGMTVRYYDTSDKLQYG 194 Query: 190 --RASTIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKN 234 + + + + + ++ + + + K KL+ +++ KK Sbjct: 195 NVKPAASLDELLKTSDVVSLHVPSS----KSTSKLITEAKLRKMKKG 237 >3L1R-A nrPDB Length = 478 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 26/54 (48%), Gaps = 7/54 (12%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGF 58 +V ++G+G + +AA L+ A I +L + GG++ T NF G Sbjct: 6 RVIVVGAGMSGISAAKRLSEAGITDLLI---LEATDHIGGRMHKT----NFAGI 52 Score = 28.0 bits (61), Expect = 5.5, Method: Composition-based stats. Identities = 13/55 (23%), Positives = 24/55 (43%), Gaps = 3/55 (5%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYG-SKVFMLVRKDHLRASTIMQKRAEKNEKIEI 207 + V+G G S A+ L++ G + + +L DH+ M K +E+ Sbjct: 4 GPRVIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGR--MHKTNFAGINVEL 56 >3ULE-B nrPDB Length = 394 Score = 30.0 bits (66), Expect = 1.6, Method: Composition-based stats. Identities = 30/137 (21%), Positives = 42/137 (30%), Gaps = 5/137 (3%) Query: 16 HTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGSELMDRMREQS 75 H+A R IK L L TT +E++ PDG +R Sbjct: 206 HSADFETVRM-IKEKLCYVGYNIEQEQKLALETTVLVESYT-LPDGRIIKVGGERFEAPE 263 Query: 76 TKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKRMHLPGEETYW 135 F +I V V ++ F + D I+L+ G S LP Sbjct: 264 ALFQPHLIN--VEGVGVAELLFNTIQAADIDTRSEFYKHIVLS-GGSTMYPGLPSRLERE 320 Query: 136 QKGISACAVCDGAVPIF 152 K + V G V Sbjct: 321 LKQLYLERVLKGDVEKL 337 >4DGK-A nrPDB Length = 501 Score = 30.0 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 12/34 (35%), Positives = 15/34 (44%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 KP VIG G A L G V +L ++D Sbjct: 2 KPTTVIGAGFGGLALAIRLQAAGIPVLLLEQRDK 35 >6H3G-A nrPDB Length = 651 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 18/41 (43%), Gaps = 2/41 (4%) Query: 4 NKVTIIGSGPAAHTAAIYLARAE--IKPILYEGMMANGIAA 42 V + G GPA A LA A+ +K +L EG N Sbjct: 7 VDVIVCGGGPAGCVVAGRLAYADPTLKVMLIEGGANNRDDP 47 >2IVE-A nrPDB Length = 478 Score = 29.6 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 12/41 (29%), Positives = 17/41 (41%) Query: 149 VPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHL 189 +P +AV+GGG S A L G+ +L L Sbjct: 11 MPRTTGMNVAVVGGGISGLAVAHHLRSRGTDAVLLESSARL 51 >1WTH-A nrPDB Length = 584 Score = 29.6 bits (65), Expect = 1.9, Method: Composition-based stats. Identities = 15/90 (16%), Positives = 26/90 (28%) Query: 160 IGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGD 219 +GG + L + + VR D + K I+ + KGD Sbjct: 458 VGGSEIYYNMDNRLHQIDGSNTIFVRGDETKTVEGNGTILVKGNVTIIVEGNADITVKGD 517 Query: 220 GKLLNALRIKNTKKNEETDLPVSGLFYAIG 249 L NT + + + +G Sbjct: 518 ATTLVEGNQTNTVNGNLSWKVAGTVDWDVG 547 >1GPJ-A nrPDB Length = 404 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 12/68 (17%), Positives = 28/68 (41%) Query: 131 EETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLR 190 E G +A + + + +K + V+G G+ A+ L G + ++ + + R Sbjct: 144 SEGAVSIGSAAVELAERELGSLHDKTVLVVGAGEMGKTVAKSLVDRGVRAVLVANRTYER 203 Query: 191 ASTIMQKR 198 A + + Sbjct: 204 AVELARDL 211 >4MIF-A nrPDB Length = 620 Score = 29.6 bits (65), Expect = 2.1, Method: Composition-based stats. Identities = 10/29 (34%), Positives = 13/29 (44%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYE 33 V I GSGP T A A ++ + E Sbjct: 15 DVFIAGSGPIGATFAKLCVDANLRVCMVE 43 >1TQY-B nrPDB Length = 415 Score = 29.2 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 52/233 (22%), Positives = 86/233 (36%), Gaps = 25/233 (10%) Query: 10 GSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPG--FPDGLTGSEL 67 G G A + +A+ R + P+ + GQ+ ++ PG P + L Sbjct: 23 GLGLAPYWSAVLDGRHGLGPVTRFDVSRYPATLAGQIDDFHAPDHIPGRLLPQTDPSTRL 82 Query: 68 M---DRMREQSTKFGTEIITETVSKV---------DLSSKPF-KLWTEFNEDAEPVTTDA 114 Q K E +T+ V D + + F KLW+E + + A Sbjct: 83 ALTAADWALQDAKADPESLTDYDMGVVTANACGGFDFTHREFRKLWSEGPKSVSVYESFA 142 Query: 115 IILA--TGASAKRMHL--PGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEA 170 A TG + R + P ++ A+ I R PL V GG DSA + Sbjct: 143 WFYAVNTGQISIRHGMRGPSSALVAEQAGGLDALGHARRTIRRGTPLVVSGGVDSALDPW 202 Query: 171 QFLTKYGSKVFMLVRKDHLRASTIMQKRAE-----KNEKIEILYNTVALEAKG 218 ++++ S + D RA +RA + I +L ++ A EA+G Sbjct: 203 GWVSQIASG-RISTATDPDRAYLPFDERAAGYVPGEGGAILVLEDSAAAEARG 254 >6IGZ-6 nrPDB Length = 267 Score = 29.2 bits (64), Expect = 2.2, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 34/107 (31%), Gaps = 9/107 (8%) Query: 53 ENFPGFPDGLTGS-------ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNE 105 E+ PG+P G+ EL + + + + + P WT+ Sbjct: 161 EHEPGYPGGIFAPFVPGDIEELKLKELKNARLSMLAFVGFVMQAQITGKGPIACWTDHLA 220 Query: 106 D--AEPVTTDAIILATGASAKRMHLPGEETYWQKGISACAVCDGAVP 150 D + + A+I GA +P + I +G P Sbjct: 221 DPFGTTIFSKAVITLGGAVKPTCQIPDHVAFQGIDIPTPCFFEGFWP 267 >1KYQ-A nrPDB Length = 274 Score = 29.2 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 8/32 (25%), Positives = 16/32 (50%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFML 183 ++K + +IGGG+ L G K+ ++ Sbjct: 11 LKDKRILLIGGGEVGLTRLYKLMPTGCKLTLV 42 >4R16-A nrPDB Length = 418 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 21/108 (19%), Positives = 35/108 (32%), Gaps = 6/108 (5%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE 215 +AV+G G A G V +R+ I + + IE + E Sbjct: 2 RIAVLGLGYIGLPTAIMFASSGYDVV----GYDIRSEVIKKINSGVAHIIEPEIDRRLKE 57 Query: 216 AKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDT 263 GKL R+++ K + + V G P + + T Sbjct: 58 VLSLGKLKVTDRVEDLKGSNVFIICVQTPL--SGDDPDLSYLERAIRT 103 >3G1U-A nrPDB Length = 437 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 19/122 (15%), Positives = 38/122 (31%), Gaps = 13/122 (10%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVA 213 K V G GD A L +G++V + T + +E + Sbjct: 212 GKTCCVCGYGDVGKGCAAALRAFGARVVV----------TEVDPINALQASMEGYQVALV 261 Query: 214 LEAKGD-GKLLNALRIKNTKKNEETDLPVSGLFYA-IGHTPATKIVAGQVDTDEAGYIKT 271 + D + + ++ IGH T+I G ++ + +++ Sbjct: 262 EDVMADAHIFVTTTGNDDIITSDHFPHMRDDAIVCNIGHF-DTEIQVGWLEANAKEHVEI 320 Query: 272 VP 273 P Sbjct: 321 KP 322 >1NP3-A nrPDB Length = 338 Score = 29.2 bits (64), Expect = 2.5, Method: Composition-based stats. Identities = 16/65 (24%), Positives = 26/65 (40%), Gaps = 7/65 (10%) Query: 139 ISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR 198 + CD + I + K +A+IG G A L G V + LR+ + + Sbjct: 3 VFYDKDCD--LSIIQGKKVAIIGYGSQGHAHACNLKDSGVDVTV-----GLRSGSATVAK 55 Query: 199 AEKNE 203 AE + Sbjct: 56 AEAHG 60 >4X3Q-A nrPDB Length = 355 Score = 29.2 bits (64), Expect = 2.6, Method: Composition-based stats. Identities = 18/90 (20%), Positives = 31/90 (34%), Gaps = 5/90 (5%) Query: 124 KRMHLPGEETYWQKGISA-----CAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGS 178 + +PG E + +G+ A V R + +GGGD+ A Sbjct: 136 RLAAVPGLEELFYRGMHAWSQLSNPVLLAQPDFTRVHRVLDVGGGDAVNAVALARAHPSL 195 Query: 179 KVFMLVRKDHLRASTIMQKRAEKNEKIEIL 208 +V +L R L + A E++ Sbjct: 196 RVTVLDRPGALEVARKTIAEAGLEERVRTH 225 >3K6J-A nrPDB Length = 460 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 34/89 (38%), Gaps = 6/89 (6%) Query: 157 LAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEA 216 +A+IGGG A G + F++VR + R ++ + + + L + + Sbjct: 57 VAIIGGGTMGKAMAICFGLAGIETFLVVRNEQ-RCKQELEVMYAREKSFKRLNDKRIEKI 115 Query: 217 KGDGKLLNALRIKNTKKNEETDLPVSGLF 245 + K+ + K DL V + Sbjct: 116 NANLKITSDFH-----KLSNCDLIVESVI 139 >5AYV-A nrPDB Length = 309 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 8/36 (22%), Positives = 17/36 (47%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRA 191 + V+G G L + G+ V ++ R++ + A Sbjct: 2 RIYVLGAGSIGSLFGALLARAGNDVTLIGRREQVDA 37 >3ULK-A nrPDB Length = 491 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 24/60 (40%), Gaps = 1/60 (1%) Query: 144 VCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNE 203 DGA + K + ++G G + + G + +RK+ + ++A +N Sbjct: 28 FADGA-SYLQGKKVVIVGCGAQGLNQGLNMRDSGLDISYALRKEAIAEKRASWRKATENG 86 >1PJS-A nrPDB Length = 457 Score = 29.2 bits (64), Expect = 2.7, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 20/31 (64%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 R++ ++GGGD A +A+ L + G+++ + Sbjct: 10 LRDRDCLIVGGGDVAERKARLLLEAGARLTV 40 >4A7P-A nrPDB Length = 446 Score = 28.8 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 15/94 (15%), Positives = 30/94 (31%), Gaps = 10/94 (10%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE 215 +A+IG G + +G +V + +K ++ + +Y Sbjct: 10 RIAMIGTGYVGLVSGACFSDFGHEVVCV--------DKDARKIELLHQNVMPIYEPGLDA 61 Query: 216 AKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIG 249 + A R+ T E +F A+G Sbjct: 62 LVA--SNVKAGRLSFTTDLAEGVKDADAVFIAVG 93 >3OPQ-A nrPDB Length = 163 Score = 28.8 bits (63), Expect = 2.8, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 35/98 (35%), Gaps = 5/98 (5%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KV I G+G AAH + A+ + + G+ GQ + + ++ G P Sbjct: 59 KVIIAGAGGAAHLPGMVAAKTTLPVL---GVPVKSSTLNGQDSLLSIVQMPAGIPVATFA 115 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTE 102 + + + F I+ T + + F+ Sbjct: 116 IGMAGA--KNAALFAASILQHTDINIAKALAEFRAEQT 151 >2HJR-A nrPDB Length = 328 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 22/124 (17%), Positives = 45/124 (36%), Gaps = 12/124 (9%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 ++ K++IIG+G T A+ L + ++ + ++ G+ G P Sbjct: 12 IMRKKISIIGAGQIGSTIALLLGQKDLGDVYMFDIIEGVPQ--GKALDLNHCMALIGSPA 69 Query: 61 GLTGSELMDRMREQSTKFGTEIITETV------SKVDLSSKPFKLWTEFNEDAEPVTTDA 114 + G + E IIT V ++ DL + K+ E+ +A Sbjct: 70 KIFG----ENNYEYLQNSDVVIITAGVPRKPNMTRSDLLTVNAKIVGSVAENVGKYCPNA 125 Query: 115 IILA 118 ++ Sbjct: 126 FVIC 129 >3VPX-A nrPDB Length = 364 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 41/131 (31%), Gaps = 15/131 (11%) Query: 55 FPGFPDGLTGSELMDRMREQSTKFGTEIIT-ETVSKVDLSSKPFKLWTEFNEDAEPVTTD 113 G P E+ IT E V + L T++ Sbjct: 83 IIGNPKTDKNDEMFRAFGRYIEGLNGRYITAEDVGTTEADMDLINLETDY---------- 132 Query: 114 AIILATGASAKRMHLPGEETYWQ--KGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQ 171 + T A A P T + G+ A A K +AV G G+ A + Sbjct: 133 --VTGTSAGAGSSGNPSPVTAYGIYYGMKAAAKEAFGDDSLAGKTVAVQGVGNVAYALCE 190 Query: 172 FLTKYGSKVFM 182 +L + G+K+ + Sbjct: 191 YLHEEGAKLII 201 >1V9L-A nrPDB Length = 421 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 18/111 (16%), Positives = 39/111 (35%), Gaps = 5/111 (4%) Query: 153 RNKPLAVIGGGDSACEEAQFLTKYGSKVFML--VRKDHLRASTIMQKRAEKNEKIEILYN 210 K +A+ G G+ A +L K G+KV + + R + + +KN+ L Sbjct: 209 EGKTVAIQGMGNVGRWTAYWLEKMGAKVIAVSDINGVAYRKEGLNVELIQKNKG---LTG 265 Query: 211 TVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQV 261 +E ++ + + D+ V + +V ++ Sbjct: 266 PALVELFTTKDNAEFVKNPDAIFKLDVDIFVPAAIENVIRGDNAGLVKARL 316 >4B2T-D nrPDB Length = 542 Score = 28.8 bits (63), Expect = 2.9, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 42/117 (35%), Gaps = 6/117 (5%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVR---KDHLRASTIMQKRAEKNEKIE-ILYN 210 K + GGG E A LT+Y + + + A ++ +N + I Sbjct: 421 KRALIAGGGAPEIELALRLTEYSRTLSGMESYCIRAFADAMEVIPSTLAENAGLNPISTV 480 Query: 211 TVALEAKGDGKLLNALRI-KNTKKNEETDLPVSGLFYAI-GHTPATKIVAGQVDTDE 265 T G+ + + K N +L V L ++ T AT+ V + D+ Sbjct: 481 TELRNRHAQGEKTTGINVRKGGISNILEELVVQPLLVSVSALTLATETVRSILKIDD 537 >5YLN-A nrPDB Length = 356 Score = 28.8 bits (63), Expect = 3.1, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 17/43 (39%), Gaps = 4/43 (9%) Query: 6 VTIIGSGPAA----HTAAIYLARAEIKPILYEGMMANGIAAGG 44 V IIGSGP TA Y I L + + ++ G Sbjct: 175 VAIIGSGPVGLAALLTAQFYSPAKLIMVDLDDNRLETALSFGA 217 >5DT9-A nrPDB Length = 387 Score = 28.8 bits (63), Expect = 3.2, Method: Composition-based stats. Identities = 18/126 (14%), Positives = 41/126 (32%), Gaps = 15/126 (11%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFM-----LVRKDHLRASTIMQKRAEKNEKIEIL 208 +K + +IG G A+ L+ G KV + + D R T ++ ++ + I + Sbjct: 123 DKTVGIIGAGQVGSYLAKCLSGIGMKVLLNDPPKQAQGDE-REFTELETLLKQADVITLH 181 Query: 209 YNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDE-AG 267 L++A ++ + + P A + + G Sbjct: 182 TPITRGGEWPTHHLIDAAILEQLRS--------DQILINAARGPVVDNAALKARLQQGDG 233 Query: 268 YIKTVP 273 + + Sbjct: 234 FTAVLD 239 >2EBD-A nrPDB Length = 309 Score = 28.8 bits (63), Expect = 3.3, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 42/113 (37%), Gaps = 9/113 (7%) Query: 139 ISACAVCDGAVPIFRNKPLAVIGGGDS--ACEE----AQFLTKYGSKVFMLVRKDHLRAS 192 I A + D + + K + VIG A + L G+ ++ R + S Sbjct: 115 IYALDIADSFIKSGKAKNVLVIGAEKLSEAVDWEDRSTCVLFGDGAGAVVVTRSED--KS 172 Query: 193 TIMQKRAEKNEKIEILYNTVALE-AKGDGKLLNALRIKNTKKNEETDLPVSGL 244 I+ R +E L + + G+ L + +++ ++ L +G+ Sbjct: 173 DILATRMYAEGSLEELLHADNCGYIRMKGRELFKVAVRSMEEVCREVLEKAGV 225 >1GUZ-A nrPDB Length = 310 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 27/158 (17%), Positives = 50/158 (31%), Gaps = 40/158 (25%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 K+T+IG+G T A LA ++ +L +E P G Sbjct: 2 KITVIGAGNVGATTAFRLAEKQLAR---------------ELVLLDVVEGIP------QG 40 Query: 65 SELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAK 124 L F T++ T N+ A+ +D +I+ G + Sbjct: 41 KALDMYESGPVGLFDTKV------------------TGSNDYADTANSDIVIITAGL-PR 81 Query: 125 RMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGG 162 + + E+ + V D + +N + V+ Sbjct: 82 KPGMTREDLLMKNAGIVKEVTDNIMKHSKNPIIIVVSN 119 >4OM8-A nrPDB Length = 309 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 14/59 (23%), Positives = 22/59 (37%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 + IIG G A LAR ++ + Y+ A A L+ + + G G Sbjct: 5 IAIIGLGTMGPGMAARLARGGLQVVAYDVAPAAIERARSMLSVAETVLDALGIALPSAG 63 >2ZXH-A nrPDB Length = 637 Score = 28.8 bits (63), Expect = 3.5, Method: Composition-based stats. Identities = 11/29 (37%), Positives = 15/29 (51%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLV 184 + VIGGG + E A + G+K M V Sbjct: 29 DVVVIGGGHAGIEAALAAARMGAKTAMFV 57 >5L46-A nrPDB Length = 841 Score = 28.4 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 9/30 (30%), Positives = 16/30 (53%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILY 32 + IIG G + A +LA+A +K ++ Sbjct: 22 RAETVIIGGGCVGVSLAYHLAKAGMKDVVL 51 >6NBK-A nrPDB Length = 297 Score = 28.4 bits (62), Expect = 4.1, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 30/64 (46%), Gaps = 4/64 (6%) Query: 136 QKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQ--FLTKYGSKVFMLVRKDHLRAST 193 G S+ GA P + + + +IG A +E + F+ G KVF + D + + Sbjct: 147 GYGHSSLVDLYGAYPKVKKENVVIIGA--RALDEGEKDFIRNEGIKVFSMHEIDRMGMTA 204 Query: 194 IMQK 197 +M++ Sbjct: 205 VMEE 208 >2DQ4-A nrPDB Length = 343 Score = 28.4 bits (62), Expect = 4.5, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 40/126 (31%), Gaps = 27/126 (21%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I G+GP AA+ + + PIL +A Sbjct: 168 VLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAF---------------------AR 206 Query: 66 ELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATGASAKR 125 DR+ E + E V +V S L NE A A+I G A+ Sbjct: 207 PYADRLVNPLE----EDLLEVVRRVTGSGVEVLLEFSGNEAAIHQGLMALI--PGGEARI 260 Query: 126 MHLPGE 131 + +P + Sbjct: 261 LGIPSD 266 Score = 27.6 bits (60), Expect = 7.8, Method: Composition-based stats. Identities = 14/101 (13%), Positives = 30/101 (29%), Gaps = 11/101 (10%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYGSKVFML-----VRKDHLRASTIMQKRAEKNEKIEIL 208 K + + G G A + G+ ++ R R + + +E++ Sbjct: 165 GKSVLITGAGPIGLMAAMVVRASGAGPILVSDPNPYRLAFARPYADRLVNPLEEDLLEVV 224 Query: 209 YNT------VALEAKGDGKLLNALRIKNTKKNEETDLPVSG 243 V LE G+ ++ + E L + Sbjct: 225 RRVTGSGVEVLLEFSGNEAAIHQGLMALIPGGEARILGIPS 265 >5JXW-A nrPDB Length = 498 Score = 28.4 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 45/98 (45%), Gaps = 10/98 (10%) Query: 142 CAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEK 201 + +G + + K + V+G G+ AQ L+ G++V ++ D + A + + + Sbjct: 259 HGLFNGCIQMLAGKKIVVLGYGEVGKGCAQGLSGVGARV-IVTEIDPICA----LQASME 313 Query: 202 NEKIEILYNTVALE-----AKGDGKLLNALRIKNTKKN 234 ++ +L + V+ A G+ ++ ++ K+N Sbjct: 314 GYQVSVLEDVVSEADIFITATGNKDVITVEHMRKMKEN 351 >4IVM-B nrPDB Length = 483 Score = 28.4 bits (62), Expect = 4.6, Method: Composition-based stats. Identities = 10/39 (25%), Positives = 20/39 (51%), Gaps = 2/39 (5%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGG 44 V ++G G + A+ +L+RA P + ++ + GG Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVV--LVESSERLGG 47 >3OZ2-A nrPDB Length = 397 Score = 28.4 bits (62), Expect = 4.7, Method: Composition-based stats. Identities = 8/25 (32%), Positives = 12/25 (48%) Query: 17 TAAIYLARAEIKPILYEGMMANGIA 41 TAA Y A+ +K ++ E G Sbjct: 18 TAARYAAKYGLKTLMIEKRPEIGSP 42 >1UPS-A nrPDB Length = 420 Score = 28.0 bits (61), Expect = 5.2, Method: Composition-based stats. Identities = 10/46 (21%), Positives = 17/46 (36%) Query: 228 IKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVP 273 +KN + E ++ + G P T A + GY + V Sbjct: 338 LKNNETGEYLNIENQTGYIEHGKVPKTWWSAQWSEVPVDGYTRFVN 383 >3IP1-A nrPDB Length = 404 Score = 28.0 bits (61), Expect = 5.3, Method: Composition-based stats. Identities = 23/143 (16%), Positives = 43/143 (30%), Gaps = 17/143 (11%) Query: 6 VTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTGS 65 V I+G GP A L A ++ +L I+ T Sbjct: 217 VVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVID--------PTKE 268 Query: 66 ELMDRMREQSTKFGTEIITETVSKV------DLSSKPFKLWTEFNEDAEPVTTDAIILAT 119 ++ + + + G ++ E + V + ++ A DA I T Sbjct: 269 NFVEAVLDYTNGLGAKLFLE-ATGVPQLVWPQIEEVIWRARGINATVAIVARADAKIPLT 327 Query: 120 GA--SAKRMHLPGEETYWQKGIS 140 G +R + G + + G Sbjct: 328 GEVFQVRRAQIVGSQGHSGHGTF 350 >3BA1-A nrPDB Length = 333 Score = 28.0 bits (61), Expect = 5.6, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 29/106 (27%), Gaps = 18/106 (16%) Query: 152 FRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNT 211 F K + +IG G A R + R++K Y + Sbjct: 162 FSGKRVGIIGLGRIGLAVA-------------ERAEAFDCPISYFSRSKKPNTNYTYYGS 208 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETDLPVS-----GLFYAIGHTP 252 V A L+ A + + + G+ IG P Sbjct: 209 VVELASNSDILVVACPLTPETTHIINREVIDALGPKGVLINIGRGP 254 >3UOG-A nrPDB Length = 363 Score = 28.0 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 20/145 (13%), Positives = 41/145 (28%), Gaps = 3/145 (2%) Query: 87 VSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG---ASAKRMHLPGEETYWQKGISACA 143 + + + + V ++ ++L G A+ K + T G++A Sbjct: 120 LDGLRPGTGRTPAYETLGGAHPGVLSEYVVLPEGWFVAAPKSLDAAEASTLPCAGLTAWF 179 Query: 144 VCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNE 203 + + V G G A Q G++V + Sbjct: 180 ALVEKGHLRAGDRVVVQGTGGVALFGLQIAKATGAEVIVTSSSREKLDRAFALGADHGIN 239 Query: 204 KIEILYNTVALEAKGDGKLLNALRI 228 ++E + GD + L I Sbjct: 240 RLEEDWVERVYALTGDRGADHILEI 264 >4G65-A nrPDB Length = 461 Score = 28.0 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 33/83 (39%), Gaps = 6/83 (7%) Query: 155 KPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVAL 214 + + ++GGG+ A+ L + V ++ R +K +E+ E + A Sbjct: 236 RRIMIVGGGNIGASLAKRLEQT-YSVKLIERN-----LQRAEKLSEELENTIVFCGDAAD 289 Query: 215 EAKGDGKLLNALRIKNTKKNEET 237 + + ++ + + NE+ Sbjct: 290 QELLTEENIDQVDVFIALTNEDE 312 >2X19-B nrPDB Length = 963 Score = 28.0 bits (61), Expect = 5.7, Method: Composition-based stats. Identities = 17/60 (28%), Positives = 20/60 (33%), Gaps = 10/60 (16%) Query: 56 PGFPDGLTGSELMDRMREQSTKFGTEIITETVSK--VDLSSKPFKLWTEFNEDAEPVTTD 113 PGFP E Q F +I+ E V+K V K F L T D Sbjct: 911 PGFPSARLSPE-------QKDTFSQQILRERVNKRRVKEMVKEFTLLCR-GLHGTDYTAD 962 >3WID-A nrPDB Length = 369 Score = 28.0 bits (61), Expect = 5.8, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 19/50 (38%) Query: 139 ISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDH 188 +S ++ F K + VIG G A + G V M+ R D Sbjct: 171 VSKRSIFQNDDSTFIGKKMVVIGSGSEAFLYSFVGKDRGFDVTMVNRHDE 220 >3GG2-A nrPDB Length = 450 Score = 28.0 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 33/94 (35%), Gaps = 10/94 (10%) Query: 156 PLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALE 215 +AV+G G A + G+ V + T K + N +Y + Sbjct: 4 DIAVVGIGYVGLVSATCFAELGANVRCI--------DTDRNKIEQLNSGTIPIYEPGLEK 55 Query: 216 AKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIG 249 + + A R++ + E+ +F A+G Sbjct: 56 MIA--RNVKAGRLRFGTEIEQAVPEADIIFIAVG 87 >6APH-A nrPDB Length = 445 Score = 27.6 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 13/83 (15%), Positives = 24/83 (28%) Query: 151 IFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEILYN 210 + K + V G GD A GS V + M+ K + Sbjct: 223 MLAGKRVVVCGFGDVGKGTAASFRGAGSIVTVTEIDPICALQAAMEGYEVKQLDTVVDNA 282 Query: 211 TVALEAKGDGKLLNALRIKNTKK 233 + + G+ ++ + K Sbjct: 283 DIIITTTGNFGIVRGEHFEKMKD 305 >4OBV-D nrPDB Length = 490 Score = 27.6 bits (60), Expect = 6.6, Method: Composition-based stats. Identities = 28/149 (18%), Positives = 50/149 (33%), Gaps = 30/149 (20%) Query: 192 STIMQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHT 251 + + R K I + T + + + LRI + +P + F Sbjct: 165 TALTAARDNKLTDINLHLGTAYISDQTHSSVAKGLRIIGITDSRIRRIPTNSHF-----Q 219 Query: 252 PATKIVAGQVDTDEA-GYIKTV----PGSSLT--------------------SVPGFFAA 286 T + ++TD+ GYI V G++ T + G + A Sbjct: 220 MDTTKLEEAIETDKKSGYIPFVVIGTAGTTNTGSIDPLTEISALCKKHDMWFHIDGAYGA 279 Query: 287 GDVQDSKYRQAITSAGSGCMAALDAEKYL 315 + KY+ +T G + DA K+L Sbjct: 280 SVLLSPKYKSLLTGTGLADSISWDAHKWL 308 >1VL1-A nrPDB Length = 232 Score = 27.6 bits (60), Expect = 7.0, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 29/70 (41%), Gaps = 1/70 (1%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDG-LT 63 + I+G GP H A+I+ K L +G ++T T N + + Sbjct: 139 DLAILGMGPDGHVASIFDLETGNKDNLVTFTDPSGDPKVPRVTLTFRALNTSLYVLFLIR 198 Query: 64 GSELMDRMRE 73 G E ++R+ E Sbjct: 199 GKEKINRLTE 208 >5YEQ-A nrPDB Length = 340 Score = 27.6 bits (60), Expect = 7.3, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 18/37 (48%) Query: 146 DGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 D ++ + + K +AV+G G A L G KV + Sbjct: 9 DVSLDVIKEKRVAVLGYGSQGRAWALNLRDSGIKVSV 45 >9LDB-A nrPDB Length = 332 Score = 27.6 bits (60), Expect = 7.4, Method: Composition-based stats. Identities = 15/66 (22%), Positives = 27/66 (40%), Gaps = 5/66 (7%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEI--KPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 HNK+T++G G AI + E+ + L + M G++ F P Sbjct: 20 HNKITVVGVGAVGMACAISILMKELADEIALVDVMEDKLK---GEMMDLQHGSLFLRTPK 76 Query: 61 GLTGSE 66 ++G + Sbjct: 77 IVSGKD 82 >2GAG-B nrPDB Length = 405 Score = 27.6 bits (60), Expect = 7.6, Method: Composition-based stats. Identities = 12/48 (25%), Positives = 19/48 (39%), Gaps = 2/48 (4%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEI 52 I+G G A +LA+ + ++ G AGG + T I Sbjct: 23 DAIIVGGGGHGLATAYFLAKNHGITNV--AVLEKGWLAGGNMARNTTI 68 >6C55-A nrPDB Length = 340 Score = 27.6 bits (60), Expect = 7.9, Method: Composition-based stats. Identities = 18/79 (22%), Positives = 31/79 (39%), Gaps = 5/79 (6%) Query: 146 DGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVR----KDHLRASTIMQ-KRAE 200 D + K +AV+G G AQ L G V + +R D + AE Sbjct: 9 DVKTDALQGKKIAVVGYGSQGHAHAQNLKDNGYDVVIGIRPGRSFDKAKEDGFDVFPVAE 68 Query: 201 KNEKIEILYNTVALEAKGD 219 ++ +++ + E +GD Sbjct: 69 AVKQADVIMVLLPDEIQGD 87 >4P9S-A nrPDB Length = 848 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 8/30 (26%), Positives = 16/30 (53%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAEIKPILY 32 + IIG G + A +LA+A ++ ++ Sbjct: 23 RAETVIIGGGCVGVSLAYHLAKAGMRDVVL 52 >2CUL-A nrPDB Length = 232 Score = 27.6 bits (60), Expect = 8.2, Method: Composition-based stats. Identities = 9/33 (27%), Positives = 17/33 (51%) Query: 1 MVHNKVTIIGSGPAAHTAAIYLARAEIKPILYE 33 M +V I+G+G + A +LA+ ++ L Sbjct: 1 MAAYQVLIVGAGFSGAETAFWLAQKGVRVGLLT 33 >3G05-A nrPDB Length = 576 Score = 27.3 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 23/64 (35%), Gaps = 11/64 (17%) Query: 127 HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFML-VR 185 +P E + +G D + +IGGG + E A + G + +L Sbjct: 15 DIPTTENLYFQGSFYPDPFD----------VIIIGGGHAGTEAAMAAARMGQQTLLLTHN 64 Query: 186 KDHL 189 D L Sbjct: 65 IDTL 68 Score = 27.3 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEI 52 V IIG G A AA+ AR + +L + GQ++ I Sbjct: 34 DVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTL----GQMSCNPAI 77 >6MO6-A nrPDB Length = 414 Score = 27.3 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 39/238 (16%), Positives = 71/238 (29%), Gaps = 39/238 (16%) Query: 101 TEFNEDAEPVTTDAIILATGAS---AKRMHLPGEETYWQKGISACAVCDG---------- 147 +D E ++ +I+A G K LP + + G + Sbjct: 87 CIHTDDDEKISYRYLIIALGIQLDYEKIKGLPEGFAHPKIGSNYSVKTVEKTWKALQDFK 146 Query: 148 ---AVPIFRNKPLAVIGGGDSACEEAQ-FLTKYGS--KVFMLVRKD-------HLRASTI 194 A+ F N P+ G ++ + K G K ++ A + Sbjct: 147 EGNAIFTFPNTPVKCAGAPQKIMYLSEAYFRKTGKRSKANIIFNTSLGAIFGVKKYADAL 206 Query: 195 MQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNT-KKNEETDLPVSGLFYAIGHTPA 253 + E+N + N +E + D +N K E + L +P Sbjct: 207 QEIIQERNLTVNYKKN--LIEVRADK---QEAVFENLDKPGETQVISYEMLHVTPPMSPP 261 Query: 254 TKIVAGQVDTDEAGYIKTVPGSSL-TSVPGFFAAGDVQDSKYRQAITSAGSGCMAALD 310 ++ D AG++ + P F GD + TS + +AA Sbjct: 262 -DVLKTSPVADAAGWVDVDKETLQHRRYPNVFGIGDCTNLP-----TSKTAAAVAAQS 313 >3CP2-A nrPDB Length = 649 Score = 27.3 bits (59), Expect = 8.4, Method: Composition-based stats. Identities = 14/48 (29%), Positives = 20/48 (41%), Gaps = 4/48 (8%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEI 52 V IIG G A AA+ AR + +L + GQ++ I Sbjct: 28 DVIIIGGGHAGTEAAMAAARMGQQTLLLTHNIDTL----GQMSCNPAI 71 >6ACF-A nrPDB Length = 367 Score = 27.3 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 12/46 (26%), Positives = 21/46 (45%) Query: 137 KGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFM 182 +G+ A A K +AV G G+ A + L + G+K+ + Sbjct: 156 RGMKAAAKEAFGSDSLEGKVVAVQGVGNVAYHLCRHLHEEGAKLIV 201 >3X0D-A nrPDB Length = 655 Score = 27.3 bits (59), Expect = 8.6, Method: Composition-based stats. Identities = 10/70 (14%), Positives = 20/70 (28%), Gaps = 3/70 (4%) Query: 143 AVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKN 202 D + + +A +G G K +V ++ + R K Sbjct: 377 KFKDEVDKLSKGLHVATVGEGSF---LGLLAAKTAKRVTIIDGNERFRDIFFKYIHYYKL 433 Query: 203 EKIEILYNTV 212 +EI+ Sbjct: 434 TNVEIIEKVT 443 >6D9T-A nrPDB Length = 400 Score = 27.3 bits (59), Expect = 8.8, Method: Composition-based stats. Identities = 8/46 (17%), Positives = 14/46 (30%) Query: 161 GGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIE 206 G G A E L + G +V + R + ++ Sbjct: 33 GSGIIATELGIKLAERGHEVHFITSNIPFRIRKPLPNMIFHQVEVN 78 >3KYD-B nrPDB Length = 551 Score = 27.3 bits (59), Expect = 9.0, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 10/24 (41%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYG 177 + V+G G CE + L G Sbjct: 19 GGRVLVVGAGGIGCELLKNLVLTG 42 >3K8Z-A nrPDB Length = 423 Score = 27.3 bits (59), Expect = 9.2, Method: Composition-based stats. Identities = 48/293 (16%), Positives = 90/293 (30%), Gaps = 72/293 (24%) Query: 5 KVTII----GSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPD 60 K II G G I ++ E + + A Q+ ++ P PD Sbjct: 103 KCGIIDLPYGGGKGG----IVCDPRDMSFRELERLSRGYVRAISQIVG--PTKDVPA-PD 155 Query: 61 GLTGSELMDRMREQSTKFGTEIITETVSKVDLSSKPFKLWTEFNEDAEPVTTDAIILATG 120 T S++M M ++ ++ ++ KP L ++ I + Sbjct: 156 VFTNSQIMAWMMDEYSRIDEFNSPGFIT-----GKPLVLGGSHGRESATAKGVTICIKEA 210 Query: 121 ASAKRMHLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKV 180 A + + + G + V G G++ A+F+ G+KV Sbjct: 211 AKKRGIDIKGA------------------------RVVVQGFGNAGSYLAKFMHDAGAKV 246 Query: 181 -------------------FMLVRKDHLRASTIMQKRAEKNEKIEILYNTVALEAKGDGK 221 ++L R+D T + + + N LE D Sbjct: 247 VGISDAYGGLYDPEGLDIDYLLDRRDSFGTVTKLFN--------DTITNQELLELDCD-- 296 Query: 222 LLNALRIKNTKKNEETDLPVSGLFYAIGHTPATKIVAGQVDTDEAGYIKTVPG 274 +L I+N E + + + P T + ++ +D I VP Sbjct: 297 ILVPAAIENQITEENAHNIRAKIVVEAANGP-TTLEGTKILSDRD--ILLVPD 346 >6DKT-A nrPDB Length = 296 Score = 27.3 bits (59), Expect = 9.3, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 31/67 (46%), Gaps = 4/67 (5%) Query: 136 QKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQ--FLTKYGSKVFMLVRKDHLRAST 193 G + +G P + + + +IG + +E + ++ + G KV+ + D L + Sbjct: 146 GIGHESLVNLEGYAPKIKPENVVIIGA--RSLDEGERKYIKESGMKVYTMHEIDRLGMTK 203 Query: 194 IMQKRAE 200 ++++ + Sbjct: 204 VIEETLD 210 >4XIY-A nrPDB Length = 338 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 28/65 (43%), Gaps = 7/65 (10%) Query: 139 ISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR 198 + CD + I ++K +A+IG G A L G V++ LRA + + Sbjct: 3 VYYDKDCD--LSIIQSKKVAIIGYGSQGHAHACNLKDSGVDVYV-----GLRAGSASVAK 55 Query: 199 AEKNE 203 AE + Sbjct: 56 AEAHG 60 >3AQ1-B nrPDB Length = 500 Score = 27.3 bits (59), Expect = 9.5, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 36/94 (38%), Gaps = 11/94 (11%) Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKR------AEKNEKIEILYNT 211 V+GGG S E + L++Y S L ++ L S + +N ++ + Sbjct: 358 VVVGGGSSEVELSLRLSEYAST---LKGREQLAVSKFAEALEVIPVALAENAGLDPI--D 412 Query: 212 VALEAKGDGKLLNALRIKNTKKNEETDLPVSGLF 245 + +E + + N N E D+ + + Sbjct: 413 IMVELRSQHEKGNKNAGLNVYTGEVVDMWENDVI 446 >3KYC-B nrPDB Length = 660 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 7/24 (29%), Positives = 10/24 (41%) Query: 154 NKPLAVIGGGDSACEEAQFLTKYG 177 + V+G G CE + L G Sbjct: 37 GGRVLVVGAGGIGCELLKNLVLTG 60 >1I8T-A nrPDB Length = 367 Score = 27.3 bits (59), Expect = 9.6, Method: Composition-based stats. Identities = 11/51 (21%), Positives = 22/51 (43%), Gaps = 4/51 (7%) Query: 158 AVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRASTIMQKRAEKNEKIEIL 208 ++G G A L K KV ++ +++H+ + + E I+I Sbjct: 5 IIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDC----EGIQIH 51 >2PA3-A nrPDB Length = 410 Score = 27.3 bits (59), Expect = 9.7, Method: Composition-based stats. Identities = 10/55 (18%), Positives = 16/55 (29%), Gaps = 2/55 (3%) Query: 127 HLPGEETYWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVF 181 +P +G+ R K L +IG G + G V+ Sbjct: 126 GVPEANAKAHRGVWNKLAAGSFEA--RGKKLGIIGYGHIGTQLGILAESLGMYVY 178 >3NEP-X nrPDB Length = 314 Score = 27.3 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 28/60 (46%), Gaps = 1/60 (1%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQLTTTTEIENFPGFPDGLTG 64 KVT+IG+G T A +AR ++ + + +G+ G L E GF +TG Sbjct: 2 KVTVIGAGNVGATVAECVARQDVAKEVVMVDIKDGMPQGKAL-DMRESSPIHGFDTRVTG 60 >1Y6J-A nrPDB Length = 318 Score = 27.3 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 14/24 (58%) Query: 3 HNKVTIIGSGPAAHTAAIYLARAE 26 +KV IIG+G +AA +A + Sbjct: 7 RSKVAIIGAGFVGASAAFTMALRQ 30 >1GV0-A nrPDB Length = 310 Score = 27.3 bits (59), Expect = 9.8, Method: Composition-based stats. Identities = 14/42 (33%), Positives = 20/42 (47%) Query: 5 KVTIIGSGPAAHTAAIYLARAEIKPILYEGMMANGIAAGGQL 46 K+T+IG+G T A LA ++ L + GI G L Sbjct: 2 KITVIGAGNVGATTAFRLAEKQLARELVLLDVVEGIPQGKAL 43 >6IUM-B nrPDB Length = 701 Score = 27.3 bits (59), Expect = 10.0, Method: Composition-based stats. Identities = 24/144 (16%), Positives = 48/144 (33%), Gaps = 7/144 (4%) Query: 134 YWQKGISACAVCDGAVPIFRNKPLAVIGGGDSACEEAQFLTKYGSKVFMLVRKDHLRAST 193 + ++ S P + + +AVIG G + G V +L K Sbjct: 272 FGERAASKIPDVPEGTPTRKIEKVAVIGAGTMGGGISMNFLNAGIPVTILETKQEALDRG 331 Query: 194 I-MQKRAEKNEKIEILYNTVALEAKGDGKLLNALRIKNTKKNEETDLPVSGLFYAIGHTP 252 + + ++ +N + +E + G L L + K DL + +F +G Sbjct: 332 VGIIRKNYENSAKKGKLTQEKVEQRM-GLLSTTLSYDDLKD---ADLIIEAVFEEMGVK- 386 Query: 253 ATKIVAGQVDTDEAGYIKTVPGSS 276 + + + G I S+ Sbjct: 387 -ETVFKKLDEVAKQGAILASNTST 409 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.313 0.142 0.373 Lambda K H 0.267 0.0431 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,755,312 Number of Sequences: 36641 Number of extensions: 452747 Number of successful extensions: 2936 Number of sequences better than 10.0: 384 Number of HSP's better than 10.0 without gapping: 354 Number of HSP's successfully gapped in prelim test: 139 Number of HSP's that attempted gapping in prelim test: 1603 Number of HSP's gapped (non-prelim): 828 length of query: 319 length of database: 10,336,785 effective HSP length: 97 effective length of query: 222 effective length of database: 6,782,608 effective search space: 1505738976 effective search space used: 1505738976 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 59 (27.3 bits)