BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P29496 (775 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5BK4-5 nrPDB 1592 0.0 4FDG-B nrPDB 352 3e-97 3F9V-A nrPDB 352 5e-97 4R7Y-A nrPDB 350 1e-96 3JC6-4 nrPDB 335 4e-92 3JC7-2 nrPDB 323 1e-88 5XF8-3 nrPDB 308 5e-84 5U8S-7 nrPDB 308 7e-84 4R7Z-A nrPDB 260 1e-69 3F8T-A nrPDB 96 9e-20 4QHS-A nrPDB 33 0.54 6ID1-L nrPDB 31 1.9 3KC2-A nrPDB 31 2.1 2ENX-A nrPDB 30 3.2 3D8B-A nrPDB 30 3.9 5T4O-A nrPDB 30 4.0 4LZZ-A nrPDB 30 4.8 1NY5-A nrPDB 30 5.8 1UM8-A nrPDB 29 6.0 1OI7-A nrPDB 29 7.0 >5BK4-5 nrPDB Length = 775 Score = 1592 bits (4121), Expect = 0.0, Method: Compositional matrix adjust. Identities = 775/775 (100%), Positives = 775/775 (100%) Query: 1 MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS 60 MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS Sbjct: 1 MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS 60 Query: 61 LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT 120 LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT Sbjct: 61 LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT 120 Query: 121 SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS 180 SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS Sbjct: 121 SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS 180 Query: 181 IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP 240 IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP Sbjct: 181 IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP 240 Query: 241 YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI 300 YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI Sbjct: 241 YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI 300 Query: 301 YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL 360 YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL Sbjct: 301 YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL 360 Query: 361 SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT 420 SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT Sbjct: 361 SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT 420 Query: 421 AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID 480 AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID Sbjct: 421 AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID 480 Query: 481 EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI 540 EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI Sbjct: 481 EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI 540 Query: 541 DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK 600 DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK Sbjct: 541 DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK 600 Query: 601 RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT 660 RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT Sbjct: 601 RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT 660 Query: 661 ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR 720 ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR Sbjct: 661 ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR 720 Query: 721 RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV 775 RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV Sbjct: 721 RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV 775 >4FDG-B nrPDB Length = 692 Score = 352 bits (903), Expect = 3e-97, Method: Compositional matrix adjust. Identities = 227/670 (33%), Positives = 353/670 (52%), Gaps = 95/670 (14%) Query: 31 FKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPL 89 F F+ F+ ++ Q Y +++ + + SL + ++ +NE++ ++ + I+P+ Sbjct: 20 FIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPI 79 Query: 90 FETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLR 149 E A+ + + D + + + I LR Sbjct: 80 LEGALY-----------------------DHILQLDPTYQRDIEKVHVRIVGIPRVIELR 116 Query: 150 DLDSEHVSKIVRLSGIIISTSVLSSR---ATYLSIMCRNCRHTTSITINNF----NSITG 202 + S + K++ + GI++ + + R ATY +H + F + Sbjct: 117 KIRSTDIGKLITIDGILVKVTPVKERIYKATY--------KHIHPDCMQEFEWPEDEEMP 168 Query: 203 NTVSLPRSCLSTIESESSMANESNIGDESTKKNCG-PDPYIIIHESSKFIDQQFLKLQEI 261 + +P C CG P + +I E +K ID Q +QE Sbjct: 169 EVLEMPTIC----------------------PKCGKPGQFRLIPEKTKLIDWQKAVIQER 206 Query: 262 PELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGV 321 PE VP G++PR L + + L + PG RV + GI I R Sbjct: 207 PEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSR---------- 256 Query: 322 AIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGN 381 A+ Y+K+ S +E S + +EE+E++ L+++P + + + +SIAPSI+G+ Sbjct: 257 AVFDIYMKV----SSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGH 312 Query: 382 EDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSG 441 ++K+A+ L GG K+L D R+RGDI++L++GDPGTAKSQ+L+F+ +V+P AVYT+G Sbjct: 313 WELKEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTG 371 Query: 442 KGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQT 501 KGS+AAGLTA+V R+ T E+YLE GA+VLADGG+ IDE DKMRDEDRVAIHEAMEQQT Sbjct: 372 KGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQT 431 Query: 502 ISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHN 561 +SIAKAGI LN+R +V+AA NP +GRY + DNI+ TILSRFD+IFI+KD Sbjct: 432 VSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPG 491 Query: 562 EERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEK 621 E+ D +AN+++++H+G + + I I+ +++YI Y R P+++ +A Sbjct: 492 EQ-DRELANYILDVHSGKSTK---------NIIDIDTLRKYIAYARKYVTPKITSEAKNL 541 Query: 622 LSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAI 681 ++ FV +RK+ T S I IT RQLEA+IRI+E+ AK+ L + AI Sbjct: 542 ITDFFVEMRKK-----SSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAI 596 Query: 682 ---RLFQAST 688 RLF S Sbjct: 597 NIMRLFLESV 606 >3F9V-A nrPDB Length = 595 Score = 352 bits (902), Expect = 5e-97, Method: Compositional matrix adjust. Identities = 213/554 (38%), Positives = 313/554 (56%), Gaps = 71/554 (12%) Query: 146 IPLRDLDSEHVSKIVRLSGIIISTSVLSSR---ATYLSIMCRNCRHTTSITINNF----N 198 I LR + S + K++ + GI++ + + R ATY +H + F + Sbjct: 101 IELRKIRSTDIGKLITIDGILVKVTPVKERIYKATY--------KHIHPDCMQEFEWPED 152 Query: 199 SITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCG-PDPYIIIHESSKFIDQQFLK 257 + +P C CG P + +I E +K ID Q Sbjct: 153 EEMPEVLEMPTIC----------------------PKCGKPGQFRLIPEKTKLIDWQKAV 190 Query: 258 LQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNG 317 +QE PE VP G++PR L + + L + PG RV + GI I R Sbjct: 191 IQERPEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSR------ 244 Query: 318 GSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPS 377 A+ Y+K+ S +E S + +EE+E++ L+++P + + + +SIAPS Sbjct: 245 ----AVFDIYMKV----SSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPS 296 Query: 378 IFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAV 437 I+G+ ++K+A+ L GG K+L D R+RGDI++L++GDPGTAKSQ+L+F+ +V+P AV Sbjct: 297 IYGHWELKEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAV 355 Query: 438 YTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAM 497 YT+GKGS+AAGLTA+V R+ T E+YLE GA+VLADGG+ IDE DKMRDEDRVAIHEAM Sbjct: 356 YTTGKGSTAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAM 415 Query: 498 EQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVK 557 EQQT+SIAKAGI LN+R +V+AA NP +GRY + DNI+ TILSRFD+IFI+K Sbjct: 416 EQQTVSIAKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILK 475 Query: 558 DDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQ 617 D E+ D +AN+++++H+G + + I I+ +++YI Y R P+++ + Sbjct: 476 DQPGEQ-DRELANYILDVHSGKSTK---------NIIDIDTLRKYIAYARKYVTPKITSE 525 Query: 618 AAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHV 677 A ++ FV +RK+ T S I IT RQLEA+IRI+E+ AK+ L Sbjct: 526 AKNLITDFFVEMRKK-----SSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDA 580 Query: 678 DEAI---RLFQAST 688 + AI RLF S Sbjct: 581 ERAINIMRLFLESV 594 >4R7Y-A nrPDB Length = 613 Score = 350 bits (899), Expect = 1e-96, Method: Compositional matrix adjust. Identities = 219/664 (32%), Positives = 343/664 (51%), Gaps = 83/664 (12%) Query: 31 FKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPL 89 F F+ F+ ++ Q Y +++ + + SL + ++ +NE++ ++ + I+P+ Sbjct: 15 FIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPI 74 Query: 90 FETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLR 149 E A+ + + D + + + I LR Sbjct: 75 LEGALY-----------------------DHILQLDPTYQRDIEKVHVRIVGIPRVIELR 111 Query: 150 DLDSEHVSKIVRLSGIIISTSVLSSR---ATYLSIMCRNCRHTTSITINNF----NSITG 202 + S + K++ + GI++ + + R ATY +H + F + Sbjct: 112 KIRSTDIGKLITIDGILVKVTPVKERIYKATY--------KHIHPDCMQEFEWPEDEEMP 163 Query: 203 NTVSLPRSCLSTIESESSMANESNIGDESTKKNCG-PDPYIIIHESSKFIDQQFLKLQEI 261 + +P C CG P + +I E +K ID Q +QE Sbjct: 164 EVLEMPTIC----------------------PKCGKPGQFRLIPEKTKLIDWQKAVIQER 201 Query: 262 PELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGV 321 PE VP G++PR L + + L + PG RV + GI I R Sbjct: 202 PEEVPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSR---------- 251 Query: 322 AIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGN 381 A+ Y+K+ S +E S + EEE+ +L++ + + + +SIAP+I+G Sbjct: 252 AVFDIYMKV----SSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGY 307 Query: 382 EDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSG 441 +++KK I L GG + LPDG RLRGDI+VLL+GDPG AKSQ+L++V ++P A+YTSG Sbjct: 308 KEVKKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSG 367 Query: 442 KGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQT 501 K SSAAGLTA+ RD T + LE GA+VLADGG IDE DKM D DR IHEA+EQQT Sbjct: 368 KSSSAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQT 427 Query: 502 ISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHN 561 ISI+KAGIT LN+RT+V+AAANP GR++ +K+P + ID T+LSRFD+IF++ D+ + Sbjct: 428 ISISKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPD 487 Query: 562 EERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEK 621 ++ D +A H++ + G + + +I E +++YI Y R P +S +A E+ Sbjct: 488 DKIDSEVARHILRVRRGESEVV-------APKIPHEILRKYIAYARKNIHPVISEEAMEE 540 Query: 622 LSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAI 681 + +V +RK + + E IPIT RQLEA+IR++E+ A++ LSPI EAI Sbjct: 541 IEKYYVRMRKSVKKTKGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAI 600 Query: 682 RLFQ 685 +L + Sbjct: 601 KLME 604 >3JC6-4 nrPDB Length = 933 Score = 335 bits (859), Expect = 4e-92, Method: Compositional matrix adjust. Identities = 226/742 (30%), Positives = 375/742 (50%), Gaps = 106/742 (14%) Query: 26 EIIKSFKNFILEFRL-----------------DSQFIYRDQLRNNILVKNYSLTVNMEHL 68 E +F+NF++ F+ D + Y QL + +L ++ +L Sbjct: 189 ECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNL 248 Query: 69 IGYN--EDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDS 126 + Y ED+Y +L + P ++I + + I +S++ +NN +D D Sbjct: 249 LAYKQTEDLYHQLLNYPQEVISIMDQTIKDCM--VSLI-----VDNN--------LDYD- 292 Query: 127 LLLNSLPT-FQLILNSNANQIP-LRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCR 184 L+ + T F + N +R+L+ + K++ L G+++ ++ + C Sbjct: 293 --LDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCN 350 Query: 185 NCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIII 244 C HT ++ I+ + P C E NE P+ +I Sbjct: 351 VCDHTMAVEIDR------GVIQEPARC------ERIDCNE-------------PNSMSLI 385 Query: 245 HESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSK 304 H F D+Q +KLQE P+ VP G+ P ++++ L + G R+ + G + + Sbjct: 386 HNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIR 445 Query: 305 NGAGSGRSGGGNGGSGV--AIRTPYIKILGIQS------DVETSSIWN------------ 344 N V ++ Y+ ++ ++ DV+TS+I Sbjct: 446 ----------ANSRQRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEV 495 Query: 345 -SVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDG 403 V T+++ + +++ LY +L SIAPSI+ ED+KK I+ L GG+ K G Sbjct: 496 EEVRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKG 555 Query: 404 MRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY 463 R RGDIN+LL GDP T+KSQ+L++V K++P VYTSGKGSSA GLTA + RD T++ Sbjct: 556 GRYRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLV 615 Query: 464 LEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAA 523 LE GA+VL+DGGV CIDEFDKM D R +HE MEQQTISIAKAGI T LN+R+S+LA+A Sbjct: 616 LESGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASA 675 Query: 524 NPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAM 583 NPI RY+ +NID +LSRFD++++V D +E+ D +A H+ N++ + Sbjct: 676 NPIGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEH 735 Query: 584 QNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTER 643 +Q + + +E + YI+Y + P ++ A +L +V +RK + + ++ Sbjct: 736 ISQDD----VLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRK---MGDDSRSDE 788 Query: 644 SSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQ- 702 I T RQLE++IR+ E+ AK++L + + V EA+RL +++ D A+ G ++ Sbjct: 789 KRITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMN 848 Query: 703 --ASGTSLSEIRRFEQELKRRL 722 +G S+ + R+ +++L R + Sbjct: 849 LVQTGKSVIQ-RKLQEDLSREI 869 >3JC7-2 nrPDB Length = 868 Score = 323 bits (829), Expect = 1e-88, Method: Compositional matrix adjust. Identities = 230/708 (32%), Positives = 352/708 (49%), Gaps = 109/708 (15%) Query: 27 IIKSFKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSD 85 I + K+F+LE+ ++ + +Y ++R + + SL VN HL + L+ P + Sbjct: 207 IARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEE 266 Query: 86 IIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTD-SLLLNSLPTFQLILNSNAN 144 ++ +F+ VA + L P+ + ++ + ++ PT Sbjct: 267 MLKIFDL----VAMEATELHY----------PDYARIHSEIHVRISDFPTI--------- 303 Query: 145 QIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNT 204 LR+L ++S +VR++G++ + + + Y+ C C + N Sbjct: 304 -YSLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEI--R 360 Query: 205 VSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPEL 264 +S +C S P+ + E + + + Q + LQE P Sbjct: 361 ISFCTNCKSK------------------------GPFRVNGEKTVYRNYQRVTLQEAPGT 396 Query: 265 VPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIR 324 VP G +PR+ + L + PG V + GIY KN G N +G + Sbjct: 397 VPPGRLPRHREVILLADLVDVSKPGEEVEVTGIY-----KNNY----DGNLNAKNGFPVF 447 Query: 325 TPYIKILGIQSDVETSSIWNS----VTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFG 380 I+ I+ ++ V +TEEEE EF ++SR+ + + + +S+APSI+G Sbjct: 448 ATIIEANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYG 507 Query: 381 NEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTS 440 + DIK A+ C L GG K + +RGDINVLLLGDPGTAKSQ+LK+VEK + AV+ + Sbjct: 508 HRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFAT 567 Query: 441 GKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQ 500 G+G+SA GLTASV++DP+T+E+ LEGGA+VLAD GV IDEFDKM D+DR +IHEAMEQQ Sbjct: 568 GQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQ 627 Query: 501 TISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDH 560 +ISI+KAGI T L +R S++AAANP GRY+ N+ ILSRFD++ +V+D Sbjct: 628 SISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLV 687 Query: 561 NEERDISIANHVINIHT------------------GNANAMQNQ---------------- 586 +EE D +A V++ H G + Q + Sbjct: 688 DEEADERLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQR 747 Query: 587 ---QEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTER 643 +EE S I E + +YI Y R K P+L +K+S + +R+ ES Sbjct: 748 QRKKEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRR-------ESIST 800 Query: 644 SSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDA 691 S PIT+R LE+I+RI ES AK+ LS +D AI++ S +DA Sbjct: 801 GSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDA 848 >5XF8-3 nrPDB Length = 997 Score = 308 bits (790), Expect = 5e-84, Method: Compositional matrix adjust. Identities = 189/520 (36%), Positives = 295/520 (56%), Gaps = 46/520 (8%) Query: 59 YSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPE 118 + + ++++ L ++ + + EP+ IP E A+T +A + + ++ + + P Sbjct: 120 HRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPW 179 Query: 119 NTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATY 178 S + A+ + R L ++H++K+V + GI+ TS++ + Sbjct: 180 KLSFKG---------------SFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPK--- 221 Query: 179 LSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGP 238 + R+ + ++ T T + + I + + E G++ T + Sbjct: 222 ---LIRSVHYAAKTGRFHYRDYTDATTT----LTTRIPTPAIYPTEDTEGNKLTTE---- 270 Query: 239 DPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY 298 + S FID Q + +QE+PE+ P G++PR++ + D L +K PG RV +VG++ Sbjct: 271 ------YGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVF 324 Query: 299 SIYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILG--IQSDVETSSIWNSVTMFTEEEEEE 356 G+G N + + +T ILG + S+ + M T+ + Sbjct: 325 ------KSLGAGGMNQSNSNTLIGFKT---LILGNTVYPLHARSTGVAARQMLTDFDIRN 375 Query: 357 FLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLG 416 +LS+ +++IL+ S+APSI+G++ IKKAI+ +LMGG +K L +G LRGDIN+L++G Sbjct: 376 INKLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVG 435 Query: 417 DPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGV 476 DP TAKSQLL+FV + +A+ T+G+GSS GLTA+V D T E LE GAMVLAD GV Sbjct: 436 DPSTAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGV 495 Query: 477 VCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSP 536 VCIDEFDKM D DRVAIHE MEQQT++IAKAGI T LN+R SV+AAANP++G+YD + P Sbjct: 496 VCIDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDP 555 Query: 537 GDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIH 576 NI ++LSRFD++F+V DD NE RD SI+ HV+ H Sbjct: 556 HQNIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTH 595 >5U8S-7 nrPDB Length = 845 Score = 308 bits (788), Expect = 7e-84, Method: Compositional matrix adjust. Identities = 202/543 (37%), Positives = 305/543 (56%), Gaps = 45/543 (8%) Query: 146 IPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNTV 205 + +R + + + +++ + GII S + ++ C C + F + T Sbjct: 225 LSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEV------FQEVNSRTF 278 Query: 206 SLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPELV 265 + C S E +N + +SKF Q K+QE+ + V Sbjct: 279 TPLSECTS----------------EECSQNQTKGQLFMSTRASKFSAFQECKIQELSQQV 322 Query: 266 PVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIRT 325 PVG +PR+L + + L + PG V + GI+ + +G +G+ T Sbjct: 323 PVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIF--------LPAPYTGFKALKAGLLTET 374 Query: 326 PYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIK 385 Y++ ++ + + ++ T + EE ++L + +Y L SIAP I+GN D+K Sbjct: 375 -YLEAQFVRQHKKKFASFS----LTSDVEERVMELITSGDVYNRLAKSIAPEIYGNLDVK 429 Query: 386 KAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSS 445 KA++ LL+GG K + DGM++RGDINV L+GDPG AKSQLLK + K+SP VYT+GKGSS Sbjct: 430 KALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICKISPRGVYTTGKGSS 489 Query: 446 AAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIA 505 GLTA+V +DP+T E LEGGA+VLAD G+ CIDEFDKM + DR AIHE MEQQTISI+ Sbjct: 490 GVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRTAIHEVMEQQTISIS 549 Query: 506 KAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERD 565 KAGI T LN+RTS+LAAANP+YGRY+ SP DNI+ +LSRFD++F++ D + + D Sbjct: 550 KAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFDILFLMLDIPSRDDD 609 Query: 566 ISIANHVINIHTGNANAMQNQQEE-NGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS 624 +A HV +H M N+Q + + + + KM+ YI Y + K P +S + + Sbjct: 610 EKLAEHVTYVH------MHNKQPDLDFTPVEPSKMREYIAYAKTK-RPVMSEAVNDYVVQ 662 Query: 625 NFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLF 684 ++ +R Q E++S + S T R L IIR++++LAKL L+ + V+EA+RL Sbjct: 663 AYIRLR-QDSKREMDS-KFSFGQATPRTLLGIIRLSQALAKLRLADMVDIDDVEEALRLV 720 Query: 685 QAS 687 + S Sbjct: 721 RVS 723 >4R7Z-A nrPDB Length = 338 Score = 260 bits (665), Expect = 1e-69, Method: Compositional matrix adjust. Identities = 135/334 (40%), Positives = 201/334 (60%), Gaps = 7/334 (2%) Query: 352 EEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDIN 411 EEE+ +L++ + + + +SIAP+I+G +++KK I L GG + LPDG RLRGDI+ Sbjct: 3 EEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGDIH 62 Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVL 471 VLL+GDPG AKSQ+L++V ++P A+YTS Sbjct: 63 VLLVGDPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 122 Query: 472 ADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYD 531 GG IDE DKM D DR IHEA+EQQTISI+KAGIT LN+RT+V+AAANP GR++ Sbjct: 123 XXGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGRFN 182 Query: 532 DLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENG 591 +K+P + ID T+LSRFD+IF++ D+ +++ D +A H++ + G + + Sbjct: 183 RMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVV-------A 235 Query: 592 SEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIR 651 +I E +++YI Y R P +S +A E++ +V +RK + + E IPIT R Sbjct: 236 PKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPITAR 295 Query: 652 QLEAIIRITESLAKLELSPIAQERHVDEAIRLFQ 685 QLEA+IR++E+ A++ LSPI EAI+L + Sbjct: 296 QLEALIRLSEAHARMRLSPIVTREDAREAIKLME 329 >3F8T-A nrPDB Length = 506 Score = 95.5 bits (236), Expect = 9e-20, Method: Compositional matrix adjust. Identities = 99/348 (28%), Positives = 160/348 (45%), Gaps = 45/348 (12%) Query: 353 EEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINV 412 E EEF +L+ L +IAP + G E++ K + L K + RL +V Sbjct: 192 ELEEFRELADKDPLT-TFARAIAP-LPGAEEVGKMLALQLFSCVGK---NSERL----HV 242 Query: 413 LLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLA 472 LL G P L ++ ++P VY + + LTA ++ D R + L GA VLA Sbjct: 243 LLAGYPVVCSEILHHVLDHLAPRGVYVDLRRTELTDLTAVLKED---RGWALRAGAAVLA 299 Query: 473 DGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDD 532 DGG++ +D + + R A+ EAM++ T+++ GI LN+R +VLAA NP G Sbjct: 300 DGGILAVDHLEGAPEPHRWALMEAMDKGTVTV--DGIA--LNARCAVLAAINP--GEQWP 353 Query: 533 LKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGS 592 P ID LS FD+I + + + EE + Sbjct: 354 SDPPIARIDLDQDFLSHFDLIAFL----------------------GVDPRPGEPEEQDT 391 Query: 593 EI-SIEKMKRYITYC-RLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITI 650 E+ S ++RY+ Y R AP L+ +A ++L + T ++ + E ++P+T Sbjct: 392 EVPSYTLLRRYLLYAIREHPAPELTEEARKRLEHWYET--RREEVEERLGMGLPTLPVTR 449 Query: 651 RQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIG 698 RQLE++ R+ ++ A++ LS + VD A L ++ A Q P G Sbjct: 450 RQLESVERLAKAHARMRLSDDVEPEDVDIAAELVD-WYLETAMQIPGG 496 >4QHS-A nrPDB Length = 267 Score = 32.7 bits (73), Expect = 0.54, Method: Compositional matrix adjust. Identities = 41/189 (21%), Positives = 74/189 (39%), Gaps = 35/189 (18%) Query: 407 RGDINVLLLGDPGTAKSQLLKFVEKVSP------IAVYTSG----------KGSSAAGLT 450 + D NV++LG G+ K + +++ SP IA+ + G T Sbjct: 36 KTDANVMILGPSGSGKEVMSRYIHNASPRKEGPFIAINCAAIPDNMLEATLFGYEKGAFT 95 Query: 451 ASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGIT 510 +VQ P G A GG + +DE +M + + ++++ + + + Sbjct: 96 GAVQACP---------GKFEQAQGGTILLDEISEMDLNLQAKLLRVLQEREVERLGSRKS 146 Query: 511 TVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDI--SI 568 L+ R VLA +N DLK F+ + R ++ + E +D + Sbjct: 147 IKLDVR--VLATSN------RDLKQYVQAGHFREDLYYRLNVFPLTWPALCERKDDIEPL 198 Query: 569 ANHVINIHT 577 ANH+I H Sbjct: 199 ANHLIERHC 207 >6ID1-L nrPDB Length = 802 Score = 31.2 bits (69), Expect = 1.9, Method: Compositional matrix adjust. Identities = 39/157 (24%), Positives = 67/157 (42%), Gaps = 28/157 (17%) Query: 582 AMQNQQEENGSEISIEKMKR------YITYCRLKCAPRL-----SPQAAEKLSSNFVTIR 630 A+Q ++E + I I+K ++ Y + P L S + + L ++F +R Sbjct: 184 ALQKRRELRAAGIEIQKKRKRKRGVDYNAEIPFEKKPALGFYDTSEENYQALDADFRKLR 243 Query: 631 KQLLINELES----------------TERSSIPITIRQLEAIIRITESLAKLEL-SPIAQ 673 +Q L EL S + S +P I Q + T+ +KL L +P Sbjct: 244 QQDLDGELRSEKEGRDRKKDKQHLKRKKESDLPSAILQTSGVSEFTKKRSKLVLPAPQIS 303 Query: 674 ERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSE 710 + + E +++ QAS + + + G N AS T LSE Sbjct: 304 DAELQEVVKVGQASEIARQTAEESGITNSASSTLLSE 340 >3KC2-A nrPDB Length = 352 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 12/39 (30%), Positives = 21/39 (53%) Query: 549 RFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQ 587 +FD + + D H+ DI I + IN G N ++N++ Sbjct: 154 KFDAVLVFNDPHDWAADIQIISDAINSENGMLNTLRNEK 192 >2ENX-A nrPDB Length = 310 Score = 30.4 bits (67), Expect = 3.2, Method: Compositional matrix adjust. Identities = 36/127 (28%), Positives = 62/127 (48%), Gaps = 8/127 (6%) Query: 403 GMRLRGDI-NVLLLGDPGTAKSQL--LKFVEKVSPIAVYTSG-----KGSSAAGLTASVQ 454 G+ L G I + LLL P T S + K + +++ + + G G++ + TA+ Sbjct: 141 GLLLSGLISDTLLLKSPTTHASDIPVAKELAELAGVNLEEYGLEMLKAGTNLSSKTAAEL 200 Query: 455 RDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLN 514 D + F L G A+ +A V I++ ++E VAI EA+ + S IT ++N Sbjct: 201 IDIDAKTFELNGEAVRVAQVNTVDINDILARQEEIEVAIQEAIVTEGYSDFVLMITDIVN 260 Query: 515 SRTSVLA 521 S + +LA Sbjct: 261 SNSEILA 267 >3D8B-A nrPDB Length = 357 Score = 30.0 bits (66), Expect = 3.9, Method: Compositional matrix adjust. Identities = 47/185 (25%), Positives = 73/185 (39%), Gaps = 43/185 (23%) Query: 364 PKLYEILTNSI---APSI---------FGNEDIKKAIVCLLMGGSKKILPDGMR-LRGDI 410 PK+ E++ N I P + F IK+ +V ++ PD LRG Sbjct: 64 PKMIELIMNEIMDHGPPVNWEDIAGVEFAKATIKEIVVWPML------RPDIFTGLRGPP 117 Query: 411 -NVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAM 469 +LL G PGT K+ + K + S G++ ++AS +T ++ EG M Sbjct: 118 KGILLFGPPGTGKTLIGKCI---------ASQSGATFFSISASS----LTSKWVGEGEKM 164 Query: 470 VLA--------DGGVVCIDEFDKMRDEDRVAIHEAME--QQTISIAKAGITTVLNSRTSV 519 V A V+ IDE D + + HE+ + + G TT R V Sbjct: 165 VRALFAVARCQQPAVIFIDEIDSLLSQRGDGEHESSRRIKTEFLVQLDGATTSSEDRILV 224 Query: 520 LAAAN 524 + A N Sbjct: 225 VGATN 229 >5T4O-A nrPDB Length = 513 Score = 30.0 bits (66), Expect = 4.0, Method: Compositional matrix adjust. Identities = 16/41 (39%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 546 ILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQ 586 I R +V + HNE +S+++ VI IH G A+AMQ + Sbjct: 12 IKQRIAQFNVVSEAHNEGTIVSVSDGVIRIH-GLADAMQGE 51 >4LZZ-A nrPDB Length = 268 Score = 29.6 bits (65), Expect = 4.8, Method: Compositional matrix adjust. Identities = 41/177 (23%), Positives = 68/177 (38%), Gaps = 27/177 (15%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY-LEGGAMV 470 VL+ G+ G K + + + K+S K A AS+ RD E + E GA Sbjct: 44 VLITGESGVGKEVVARLIHKLS-----DRSKEPFVALNVASIPRDIFEAELFGYEKGAFT 98 Query: 471 -----------LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSV 519 LADGG + +DE ++ E + + +E + G + + Sbjct: 99 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 156 Query: 520 LAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERD--ISIANHVIN 574 LAA N ++K F+ + R +I I E ++ I +ANH + Sbjct: 157 LAATN------RNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLK 207 >1NY5-A nrPDB Length = 387 Score = 29.6 bits (65), Expect = 5.8, Method: Compositional matrix adjust. Identities = 41/177 (23%), Positives = 68/177 (38%), Gaps = 27/177 (15%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY-LEGGAMV 470 VL+ G+ G K + + + K+S K A AS+ RD E + E GA Sbjct: 163 VLITGESGVGKEVVARLIHKLS-----DRSKEPFVALNVASIPRDIFEAELFGYEKGAFT 217 Query: 471 -----------LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSV 519 LADGG + +DE ++ E + + +E + G + + Sbjct: 218 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 275 Query: 520 LAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERD--ISIANHVIN 574 LAA N ++K F+ + R +I I E ++ I +ANH + Sbjct: 276 LAATN------RNIKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLK 326 >1UM8-A nrPDB Length = 376 Score = 29.3 bits (64), Expect = 6.0, Method: Compositional matrix adjust. Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 7/109 (6%) Query: 411 NVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGS-SAAGLTASVQRDPMTREFYLEGGAM 469 N+LL+G G+ K+ + + + K I + S S + AG + +TR + Sbjct: 74 NILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNV 133 Query: 470 VLADGGVVCIDEFDKM------RDEDRVAIHEAMEQQTISIAKAGITTV 512 A G+V IDE DK+ R R E ++Q + I + + + Sbjct: 134 QKAQKGIVFIDEIDKISRLSENRSITRDVSGEGVQQALLKIVEGSLVNI 182 >1OI7-A nrPDB Length = 288 Score = 29.3 bits (64), Expect = 7.0, Method: Compositional matrix adjust. Identities = 18/56 (32%), Positives = 30/56 (53%), Gaps = 4/56 (7%) Query: 381 NEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIA 436 + +KK +V + G S P G R+ G +++G+ GT +S+L F E P+A Sbjct: 222 KDHMKKPVVGFIGGRSA---PKGKRM-GHAGAIIMGNVGTPESKLRAFAEAGIPVA 273 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5BK4-5 nrPDB 1051 0.0 4R7Y-A nrPDB 759 0.0 4FDG-B nrPDB 724 0.0 3F9V-A nrPDB 720 0.0 3JC6-4 nrPDB 695 0.0 3JC7-2 nrPDB 647 0.0 5XF8-3 nrPDB 568 e-162 5U8S-7 nrPDB 548 e-156 4R7Z-A nrPDB 423 e-118 3F8T-A nrPDB 340 2e-93 Sequences not found previously or not previously below threshold: 4QHS-A nrPDB 41 0.001 5EXS-A nrPDB 40 0.003 2R44-A nrPDB 40 0.005 5EXX-A nrPDB 39 0.006 3DZD-A nrPDB 39 0.009 6ED3-A nrPDB 38 0.014 1OFI-A nrPDB 36 0.048 1NY5-A nrPDB 35 0.096 4LZZ-A nrPDB 35 0.10 4M9Z-A nrPDB 35 0.16 1IN6-A nrPDB 34 0.18 4BS1-B nrPDB 34 0.24 4L4U-A nrPDB 34 0.25 5W0T-A nrPDB 34 0.28 4FQJ-A nrPDB 34 0.28 3M6A-A nrPDB 33 0.49 4YPL-A nrPDB 33 0.64 4I5O-A nrPDB 33 0.73 4PA8-A nrPDB 33 0.75 1OJL-A nrPDB 33 0.80 5C3C-A nrPDB 32 0.83 1QVR-A nrPDB 32 0.89 1HQC-A nrPDB 32 1.0 1MKY-A nrPDB 32 1.0 4M44-A nrPDB 32 1.1 5AOU-A nrPDB 32 1.1 4YPN-A nrPDB 32 1.3 4PEK-A nrPDB 32 1.3 3U5Z-B nrPDB 32 1.4 1UM8-A nrPDB 31 1.8 4BL8-A nrPDB 31 2.5 3KC2-A nrPDB 31 2.6 2D2N-C nrPDB 31 2.6 4ZPX-A nrPDB 30 3.2 4QMD-A nrPDB 30 3.9 4F8X-A nrPDB 30 4.2 3K1J-A nrPDB 30 4.5 4NMI-A nrPDB 29 6.2 4TMA-B nrPDB 29 7.5 4HSE-A nrPDB 29 7.6 >5BK4-5 nrPDB Length = 775 Score = 1051 bits (2718), Expect = 0.0, Method: Composition-based stats. Identities = 775/775 (100%), Positives = 775/775 (100%) Query: 1 MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS 60 MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS Sbjct: 1 MSFDRPEIYSAPVLQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYS 60 Query: 61 LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT 120 LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT Sbjct: 61 LTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENT 120 Query: 121 SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS 180 SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS Sbjct: 121 SMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLS 180 Query: 181 IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP 240 IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP Sbjct: 181 IMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDP 240 Query: 241 YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI 300 YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI Sbjct: 241 YIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSI 300 Query: 301 YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL 360 YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL Sbjct: 301 YNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQL 360 Query: 361 SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT 420 SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT Sbjct: 361 SRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGT 420 Query: 421 AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID 480 AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID Sbjct: 421 AKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCID 480 Query: 481 EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI 540 EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI Sbjct: 481 EFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNI 540 Query: 541 DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK 600 DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK Sbjct: 541 DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMK 600 Query: 601 RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT 660 RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT Sbjct: 601 RYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRIT 660 Query: 661 ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR 720 ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR Sbjct: 661 ESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELKR 720 Query: 721 RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV 775 RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV Sbjct: 721 RLPIGWSTSYQTLRREFVDTHRFSQLALDKALYALEKHETIQLRHQGQNIYRSGV 775 >4R7Y-A nrPDB Length = 613 Score = 759 bits (1958), Expect = 0.0, Method: Composition-based stats. Identities = 217/670 (32%), Positives = 342/670 (51%), Gaps = 77/670 (11%) Query: 31 FKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPL 89 F F+ F+ ++ Q Y +++ + + SL + ++ +NE++ ++ + I+P+ Sbjct: 15 FIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPI 74 Query: 90 FETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLR 149 E A+ + D + + + I LR Sbjct: 75 LEGALYD-----------------------HILQLDPTYQRDIEKVHVRIVGIPRVIELR 111 Query: 150 DLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNF----NSITGNTV 205 + S + K++ + GI++ + + R + +H + F + + Sbjct: 112 KIRSTDIGKLITIDGILVKVTPVKERIYKATY-----KHIHPDCMQEFEWPEDEEMPEVL 166 Query: 206 SLPRSCLSTIESESSMANESNIGDESTKKNCG-PDPYIIIHESSKFIDQQFLKLQEIPEL 264 +P C CG P + +I E +K ID Q +QE PE Sbjct: 167 EMPTIC----------------------PKCGKPGQFRLIPEKTKLIDWQKAVIQERPEE 204 Query: 265 VPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIR 324 VP G++PR L + + L + PG RV + GI I R A+ Sbjct: 205 VPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSR----------AVF 254 Query: 325 TPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDI 384 Y+K+ S +E S + EEE+ +L++ + + + +SIAP+I+G +++ Sbjct: 255 DIYMKV----SSIEVSQKVLQELEISPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEV 310 Query: 385 KKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGS 444 KK I L GG + LPDG RLRGDI+VLL+GDPG AKSQ+L++V ++P A+YTSGK S Sbjct: 311 KKGIALALFGGVSRKLPDGTRLRGDIHVLLVGDPGVAKSQILRYVANLAPRAIYTSGKSS 370 Query: 445 SAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISI 504 SAAGLTA+ RD T + LE GA+VLADGG IDE DKM D DR IHEA+EQQTISI Sbjct: 371 SAAGLTAAAVRDEFTGGWVLEAGALVLADGGYALIDELDKMSDRDRSVIHEALEQQTISI 430 Query: 505 AKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEER 564 +KAGIT LN+RT+V+AAANP GR++ +K+P + ID T+LSRFD+IF++ D+ +++ Sbjct: 431 SKAGITATLNARTTVIAAANPKQGRFNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKI 490 Query: 565 DISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS 624 D +A H++ + G + + +I E +++YI Y R P +S +A E++ Sbjct: 491 DSEVARHILRVRRGESEVV-------APKIPHEILRKYIAYARKNIHPVISEEAMEEIEK 543 Query: 625 NFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLF 684 +V +RK + + E IPIT RQLEA+IR++E+ A++ LSPI EAI+L Sbjct: 544 YYVRMRKSVKKTKGEEEGIPPIPITARQLEALIRLSEAHARMRLSPIVTREDAREAIKLM 603 Query: 685 QASTMDAASQ 694 + + A Sbjct: 604 EYTLKQIAMD 613 >4FDG-B nrPDB Length = 692 Score = 724 bits (1869), Expect = 0.0, Method: Composition-based stats. Identities = 221/680 (32%), Positives = 352/680 (51%), Gaps = 86/680 (12%) Query: 31 FKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPL 89 F F+ F+ ++ Q Y +++ + + SL + ++ +NE++ ++ + I+P+ Sbjct: 20 FIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPI 79 Query: 90 FETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLR 149 E A+ + D + + + I LR Sbjct: 80 LEGALYD-----------------------HILQLDPTYQRDIEKVHVRIVGIPRVIELR 116 Query: 150 DLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNF----NSITGNTV 205 + S + K++ + GI++ + + R + +H + F + + Sbjct: 117 KIRSTDIGKLITIDGILVKVTPVKERIYKATY-----KHIHPDCMQEFEWPEDEEMPEVL 171 Query: 206 SLPRSCLSTIESESSMANESNIGDESTKKNCG-PDPYIIIHESSKFIDQQFLKLQEIPEL 264 +P C CG P + +I E +K ID Q +QE PE Sbjct: 172 EMPTIC----------------------PKCGKPGQFRLIPEKTKLIDWQKAVIQERPEE 209 Query: 265 VPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIR 324 VP G++PR L + + L + PG RV + GI I R A+ Sbjct: 210 VPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSR----------AVF 259 Query: 325 TPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDI 384 Y+K+ S +E S + +EE+E++ L+++P + + + +SIAPSI+G+ ++ Sbjct: 260 DIYMKV----SSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWEL 315 Query: 385 KKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGS 444 K+A+ L GG K+L D R+RGDI++L++GDPGTAKSQ+L+F+ +V+P AVYT+GKGS Sbjct: 316 KEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGS 374 Query: 445 SAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISI 504 +AAGLTA+V R+ T E+YLE GA+VLADGG+ IDE DKMRDEDRVAIHEAMEQQT+SI Sbjct: 375 TAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSI 434 Query: 505 AKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEER 564 AKAGI LN+R +V+AA NP +GRY + DNI+ TILSRFD+IFI+KD E+ Sbjct: 435 AKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQ- 493 Query: 565 DISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS 624 D +AN+++++H+G + + I I+ +++YI Y R P+++ +A ++ Sbjct: 494 DRELANYILDVHSGKSTK---------NIIDIDTLRKYIAYARKYVTPKITSEAKNLITD 544 Query: 625 NFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLF 684 FV +RK+ T S I IT RQLEA+IRI+E+ AK+ L + AI + Sbjct: 545 FFVEMRKK-----SSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIM 599 Query: 685 QASTMDAASQDPIGGLNQAS 704 + G ++ + Sbjct: 600 RLFLESVGVDMESGKIDIDT 619 >3F9V-A nrPDB Length = 595 Score = 720 bits (1859), Expect = 0.0, Method: Composition-based stats. Identities = 220/661 (33%), Positives = 348/661 (52%), Gaps = 86/661 (13%) Query: 31 FKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSDIIPL 89 F F+ F+ ++ Q Y +++ + + SL + ++ +NE++ ++ + I+P+ Sbjct: 8 FIEFLTTFKGNNNQNKYIERINELVAYRKKSLIIEFSDVLSFNENLAYEIINNTKIILPI 67 Query: 90 FETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNSLPTFQLILNSNANQIPLR 149 E A+ + D + + + I LR Sbjct: 68 LEGALYD-----------------------HILQLDPTYQRDIEKVHVRIVGIPRVIELR 104 Query: 150 DLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNF----NSITGNTV 205 + S + K++ + GI++ + + R + +H + F + + Sbjct: 105 KIRSTDIGKLITIDGILVKVTPVKERIYKATY-----KHIHPDCMQEFEWPEDEEMPEVL 159 Query: 206 SLPRSCLSTIESESSMANESNIGDESTKKNCG-PDPYIIIHESSKFIDQQFLKLQEIPEL 264 +P C CG P + +I E +K ID Q +QE PE Sbjct: 160 EMPTIC----------------------PKCGKPGQFRLIPEKTKLIDWQKAVIQERPEE 197 Query: 265 VPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIR 324 VP G++PR L + + L + PG RV + GI I R A+ Sbjct: 198 VPSGQLPRQLEIILEDDLVDSARPGDRVKVTGILDIKQDSPVKRGSR----------AVF 247 Query: 325 TPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDI 384 Y+K+ S +E S + +EE+E++ L+++P + + + +SIAPSI+G+ ++ Sbjct: 248 DIYMKV----SSIEVSQKVLDEVIISEEDEKKIKDLAKDPWIRDRIISSIAPSIYGHWEL 303 Query: 385 KKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGS 444 K+A+ L GG K+L D R+RGDI++L++GDPGTAKSQ+L+F+ +V+P AVYT+GKGS Sbjct: 304 KEALALALFGGVPKVLED-TRIRGDIHILIIGDPGTAKSQMLQFISRVAPRAVYTTGKGS 362 Query: 445 SAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISI 504 +AAGLTA+V R+ T E+YLE GA+VLADGG+ IDE DKMRDEDRVAIHEAMEQQT+SI Sbjct: 363 TAAGLTAAVVREKGTGEYYLEAGALVLADGGIAVIDEIDKMRDEDRVAIHEAMEQQTVSI 422 Query: 505 AKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEER 564 AKAGI LN+R +V+AA NP +GRY + DNI+ TILSRFD+IFI+KD E+ Sbjct: 423 AKAGIVAKLNARAAVIAAGNPKFGRYISERPVSDNINLPPTILSRFDLIFILKDQPGEQ- 481 Query: 565 DISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS 624 D +AN+++++H+G + + I I+ +++YI Y R P+++ +A ++ Sbjct: 482 DRELANYILDVHSGKSTK---------NIIDIDTLRKYIAYARKYVTPKITSEAKNLITD 532 Query: 625 NFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLF 684 FV +RK+ T S I IT RQLEA+IRI+E+ AK+ L + AI + Sbjct: 533 FFVEMRKK-----SSETPDSPILITPRQLEALIRISEAYAKMALKAEVTREDAERAINIM 587 Query: 685 Q 685 + Sbjct: 588 R 588 >3JC6-4 nrPDB Length = 933 Score = 695 bits (1793), Expect = 0.0, Method: Composition-based stats. Identities = 225/764 (29%), Positives = 380/764 (49%), Gaps = 109/764 (14%) Query: 26 EIIKSFKNFILEFRL-----------------DSQFIYRDQLRNNILVKNYSLTVNMEHL 68 E +F+NF++ F+ D + Y QL + +L ++ +L Sbjct: 189 ECTTNFRNFLMSFKYKFRKILDEREEFINNTTDEELYYIKQLNEMRELGTSNLNLDARNL 248 Query: 69 IGYN--EDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDS 126 + Y ED+Y +L + P ++I + + I + + + ++D D Sbjct: 249 LAYKQTEDLYHQLLNYPQEVISIMDQTIKDCMVSLIV---------------DNNLDYD- 292 Query: 127 LLLNSLPT-FQLILNSNANQIP-LRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCR 184 L+ + T F + N +R+L+ + K++ L G+++ ++ + C Sbjct: 293 --LDEIETKFYKVRPYNVGSCKGMRELNPNDIDKLINLKGLVLRSTPVIPDMKVAFFKCN 350 Query: 185 NCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIII 244 C HT ++ I+ + P C E NE P+ +I Sbjct: 351 VCDHTMAVEIDR------GVIQEPARC------ERIDCNE-------------PNSMSLI 385 Query: 245 HESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSK 304 H F D+Q +KLQE P+ VP G+ P ++++ L + G R+ + G + + Sbjct: 386 HNRCSFADKQVIKLQETPDFVPDGQTPHSISLCVYDELVDSCRAGDRIEVTGTFRSIPIR 445 Query: 305 NGAGSGRSGGGNGGSGVAIRTPYIKILGIQS------DVETSSIWNS------------- 345 + ++ Y+ ++ ++ DV+TS+I Sbjct: 446 ANSR--------QRVLKSLYKTYVDVVHVKKVSDKRLDVDTSTIEQELMQNKVDHNEVEE 497 Query: 346 VTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMR 405 V T+++ + +++ LY +L SIAPSI+ ED+KK I+ L GG+ K G R Sbjct: 498 VRQITDQDLAKIREVAAREDLYSLLARSIAPSIYELEDVKKGILLQLFGGTNKTFTKGGR 557 Query: 406 LRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLE 465 RGDIN+LL GDP T+KSQ+L++V K++P VYTSGKGSSA GLTA + RD T++ LE Sbjct: 558 YRGDINILLCGDPSTSKSQILQYVHKITPRGVYTSGKGSSAVGLTAYITRDVDTKQLVLE 617 Query: 466 GGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANP 525 GA+VL+DGGV CIDEFDKM D R +HE MEQQTISIAKAGI T LN+R+S+LA+ANP Sbjct: 618 SGALVLSDGGVCCIDEFDKMSDSTRSVLHEVMEQQTISIAKAGIITTLNARSSILASANP 677 Query: 526 IYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQN 585 I RY+ +NID +LSRFD++++V D +E+ D +A H+ N++ + + Sbjct: 678 IGSRYNPNLPVTENIDLPPPLLSRFDLVYLVLDKVDEKNDRELAKHLTNLYLEDKPEHIS 737 Query: 586 QQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSS 645 Q + + +E + YI+Y + P ++ A +L +V +RK + + ++ Sbjct: 738 QDD----VLPVEFLTMYISYAKEHIHPIITEAAKTELVRAYVGMRK---MGDDSRSDEKR 790 Query: 646 IPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQ--- 702 I T RQLE++IR+ E+ AK++L + + V EA+RL +++ D A+ G ++ Sbjct: 791 ITATTRQLESMIRLAEAHAKMKLKNVVELEDVQEAVRLIRSAIKDYATDPKTGKIDMNLV 850 Query: 703 ASGTSLSEIRRFEQELKRRLPIGWSTSYQTLRREFVDTHRFSQL 746 +G S+ + R+ +++L R + L+ + D+ F++L Sbjct: 851 QTGKSVIQ-RKLQEDLSREI-------MNVLKDQASDSMSFNEL 886 >3JC7-2 nrPDB Length = 868 Score = 647 bits (1669), Expect = 0.0, Method: Composition-based stats. Identities = 228/708 (32%), Positives = 350/708 (49%), Gaps = 109/708 (15%) Query: 27 IIKSFKNFILEFRLDS-QFIYRDQLRNNILVKNYSLTVNMEHLIGYNEDIYKKLSDEPSD 85 I + K+F+LE+ ++ + +Y ++R + + SL VN HL + L+ P + Sbjct: 207 IARELKSFLLEYTDETGRSVYGARIRTLGEMNSESLEVNYRHLAESKAILALFLAKCPEE 266 Query: 86 IIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTD-SLLLNSLPTFQLILNSNAN 144 ++ +F+ VA + L P+ + ++ + ++ PT Sbjct: 267 MLKIFDL----VAMEATELHY----------PDYARIHSEIHVRISDFPTIY-------- 304 Query: 145 QIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTSITINNFNSITGNT 204 LR+L ++S +VR++G++ + + + Y+ C C + N Sbjct: 305 --SLRELRESNLSSLVRVTGVVTRRTGVFPQLKYVKFNCLKCGSILGPFFQDSNEEI--R 360 Query: 205 VSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQFLKLQEIPEL 264 +S +C S P+ + E + + + Q + LQE P Sbjct: 361 ISFCTNCKSK------------------------GPFRVNGEKTVYRNYQRVTLQEAPGT 396 Query: 265 VPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGRSGGGNGGSGVAIR 324 VP G +PR+ + L + PG V + GIY + G N +G + Sbjct: 397 VPPGRLPRHREVILLADLVDVSKPGEEVEVTGIY---------KNNYDGNLNAKNGFPVF 447 Query: 325 TPYIKILGIQSDVETSSIWNS----VTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFG 380 I+ I+ ++ V +TEEEE EF ++SR+ + + + +S+APSI+G Sbjct: 448 ATIIEANSIKRREGNTANEGEEGLDVFSWTEEEEREFRKISRDRGIIDKIISSMAPSIYG 507 Query: 381 NEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTS 440 + DIK A+ C L GG K + +RGDINVLLLGDPGTAKSQ+LK+VEK + AV+ + Sbjct: 508 HRDIKTAVACSLFGGVPKNVNGKHSIRGDINVLLLGDPGTAKSQILKYVEKTAHRAVFAT 567 Query: 441 GKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQ 500 G+G+SA GLTASV++DP+T+E+ LEGGA+VLAD GV IDEFDKM D+DR +IHEAMEQQ Sbjct: 568 GQGASAVGLTASVRKDPITKEWTLEGGALVLADKGVCLIDEFDKMNDQDRTSIHEAMEQQ 627 Query: 501 TISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDH 560 +ISI+KAGI T L +R S++AAANP GRY+ N+ ILSRFD++ +V+D Sbjct: 628 SISISKAGIVTTLQARCSIIAAANPNGGRYNSTLPLAQNVSLTEPILSRFDILCVVRDLV 687 Query: 561 NEERDISIANHVINIHT------------------GNANAMQNQQ--------------- 587 +EE D +A V++ H G + Q + Sbjct: 688 DEEADERLATFVVDSHVRSHPENDEDREGEELKNNGESAIEQGEDEINEQLNARQRRLQR 747 Query: 588 ----EENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTER 643 EE S I E + +YI Y R K P+L +K+S + +R+ ES Sbjct: 748 QRKKEEEISPIPQELLMKYIHYARTKIYPKLHQMDMDKVSRVYADLRR-------ESIST 800 Query: 644 SSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDA 691 S PIT+R LE+I+RI ES AK+ LS +D AI++ S +DA Sbjct: 801 GSFPITVRHLESILRIAESFAKMRLSEFVSSYDLDRAIKVVVDSFVDA 848 >5XF8-3 nrPDB Length = 997 Score = 568 bits (1463), Expect = e-162, Method: Composition-based stats. Identities = 214/695 (30%), Positives = 344/695 (49%), Gaps = 114/695 (16%) Query: 59 YSLTVNMEHLIGYNEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPE 118 + + ++++ L ++ + + EP+ IP E A+T +A + + ++ + + P Sbjct: 120 HRIIISLDDLREFDRSFWSGILVEPAYFIPPAEKALTDLADSMDDVPHPNASAVSSRHPW 179 Query: 119 NTSMDTDSLLLNSLPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATY 178 S + A+ + R L ++H++K+V + GI+ TS++ + Sbjct: 180 KLSFKG---------------SFGAHALSPRTLTAQHLNKLVSVEGIVTKTSLVRPKL-- 222 Query: 179 LSIMCRNCRHTTSITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGP 238 R+ + ++ T T +L + I + + E G++ T + Sbjct: 223 ----IRSVHYAAKTGRFHYRDYTDATTTL----TTRIPTPAIYPTEDTEGNKLTTE---- 270 Query: 239 DPYIIIHESSKFIDQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY 298 + S FID Q + +QE+PE+ P G++PR++ + D L +K PG RV +VG++ Sbjct: 271 ------YGYSTFIDHQRITVQEMPEMAPAGQLPRSIDVILDDDLVDKTKPGDRVNVVGVF 324 Query: 299 SIYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFL 358 G+G N + + I + S+ + M T+ + Sbjct: 325 ------KSLGAGGMNQSNSNTLIG-FKTLILGNTVYPLHARSTGVAARQMLTDFDIRNIN 377 Query: 359 QLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDP 418 +LS+ +++IL+ S+APSI+G++ IKKAI+ +LMGG +K L +G LRGDIN+L++GDP Sbjct: 378 KLSKKKDIFDILSQSLAPSIYGHDHIKKAILLMLMGGVEKNLENGSHLRGDINILMVGDP 437 Query: 419 GTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVC 478 TAKSQLL+FV + +A+ T+G+GSS GLTA+V D T E LE GAMVLAD GVVC Sbjct: 438 STAKSQLLRFVLNTASLAIATTGRGSSGVGLTAAVTTDRETGERRLEAGAMVLADRGVVC 497 Query: 479 IDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGD 538 IDEFDKM D DRVAIHE MEQQT++IAKAGI T LN+R SV+AAANP++G+YD + P Sbjct: 498 IDEFDKMTDVDRVAIHEVMEQQTVTIAKAGIHTTLNARCSVIAAANPVFGQYDVNRDPHQ 557 Query: 539 NIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHT--------------------- 577 NI ++LSRFD++F+V DD NE RD SI+ HV+ H Sbjct: 558 NIALPDSLLSRFDLLFVVTDDINEIRDRSISEHVLRTHRYLPPGYLEGEPVRERLNLSLA 617 Query: 578 ---------------GNANAMQNQQEEN------------------------GSEIS--- 595 G + + +E+ G+EI Sbjct: 618 VGEDADINPEEHSNSGAGVENEGEDDEDHVFEKFNPLLQAGAKLAKNKGNYNGTEIPKLV 677 Query: 596 -IEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLE 654 I +++Y+ Y + + P+L+ +A + N+ +R + PIT R LE Sbjct: 678 TIPFLRKYVQYAKERVIPQLTQEAINVIVKNYTDLRNDDNTKKS--------PITARTLE 729 Query: 655 AIIRITESLAKLELSPIAQERHVDEAIRLFQASTM 689 +IR+ + AK+ LS + A L + + + Sbjct: 730 TLIRLATAHAKVRLSKTVNKVDAKVAANLLRFALL 764 >5U8S-7 nrPDB Length = 845 Score = 548 bits (1412), Expect = e-156, Method: Composition-based stats. Identities = 211/616 (34%), Positives = 322/616 (52%), Gaps = 51/616 (8%) Query: 72 NEDIYKKLSDEPSDIIPLFETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLLLNS 131 NE + L D D A+ +V + + L + L N Sbjct: 159 NEIRSENLMDTTMDPPSSMNDALREVVEDETELFPPNLTR-------RYFLYFKPLSQNC 211 Query: 132 LPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGIIISTSVLSSRATYLSIMCRNCRHTTS 191 ++ S + + +R + + + +++ + GII S + ++ C C + Sbjct: 212 ARRYRKKAIS-SKPLSVRQIKGDFLGQLITVRGIITRVSDVKPAVEVIAYTCDQCGYEV- 269 Query: 192 ITINNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFI 251 F + T + C S E +N + +SKF Sbjct: 270 -----FQEVNSRTFTPLSECTS----------------EECSQNQTKGQLFMSTRASKFS 308 Query: 252 DQQFLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIYSIYNSKNGAGSGR 311 Q K+QE+ + VPVG +PR+L + + L + PG V + GI+ + Sbjct: 309 AFQECKIQELSQQVPVGHIPRSLNIHVNGTLVRSLSPGDIVDVTGIF--------LPAPY 360 Query: 312 SGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILT 371 +G +G+ T Y++ ++ + + ++ T + EE ++L + +Y L Sbjct: 361 TGFKALKAGLLTET-YLEAQFVRQHKKKFASFS----LTSDVEERVMELITSGDVYNRLA 415 Query: 372 NSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEK 431 SIAP I+GN D+KKA++ LL+GG K + DGM++RGDINV L+GDPG AKSQLLK + K Sbjct: 416 KSIAPEIYGNLDVKKALLLLLVGGVDKRVGDGMKIRGDINVCLMGDPGVAKSQLLKAICK 475 Query: 432 VSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRV 491 +SP VYT+GKGSS GLTA+V +DP+T E LEGGA+VLAD G+ CIDEFDKM + DR Sbjct: 476 ISPRGVYTTGKGSSGVGLTAAVMKDPVTDEMILEGGALVLADNGICCIDEFDKMDESDRT 535 Query: 492 AIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFD 551 AIHE MEQQTISI+KAGI T LN+RTS+LAAANP+YGRY+ SP DNI+ +LSRFD Sbjct: 536 AIHEVMEQQTISISKAGINTTLNARTSILAAANPLYGRYNPRLSPLDNINLPAALLSRFD 595 Query: 552 MIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCA 611 ++F++ D + + D +A HV +H Q + + + + KM+ YI Y + K Sbjct: 596 ILFLMLDIPSRDDDEKLAEHVTYVHM-----HNKQPDLDFTPVEPSKMREYIAYAKTK-R 649 Query: 612 PRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPI 671 P +S + + ++ +R Q E++S + S T R L IIR++++LAKL L+ + Sbjct: 650 PVMSEAVNDYVVQAYIRLR-QDSKREMDS-KFSFGQATPRTLLGIIRLSQALAKLRLADM 707 Query: 672 AQERHVDEAIRLFQAS 687 V+EA+RL + S Sbjct: 708 VDIDDVEEALRLVRVS 723 >4R7Z-A nrPDB Length = 338 Score = 423 bits (1088), Expect = e-118, Method: Composition-based stats. Identities = 136/345 (39%), Positives = 204/345 (59%), Gaps = 7/345 (2%) Query: 350 TEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGD 409 + EEE+ +L++ + + + +SIAP+I+G +++KK I L GG + LPDG RLRGD Sbjct: 1 SPEEEQIIKELAKRKDIVDAIVDSIAPAIYGYKEVKKGIALALFGGVSRKLPDGTRLRGD 60 Query: 410 INVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAM 469 I+VLL+GDPG AKSQ+L++V ++P A+YTS Sbjct: 61 IHVLLVGDPGVAKSQILRYVANLAPRAIYTSXXXXXXXXXXXXXXXXXXXXXXXXXXXXX 120 Query: 470 VLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGR 529 GG IDE DKM D DR IHEA+EQQTISI+KAGIT LN+RT+V+AAANP GR Sbjct: 121 XXXXGGYALIDELDKMSDRDRSVIHEALEQQTISISKAGITATLNARTTVIAAANPKQGR 180 Query: 530 YDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEE 589 ++ +K+P + ID T+LSRFD+IF++ D+ +++ D +A H++ + G + + Sbjct: 181 FNRMKNPFEQIDLPPTLLSRFDLIFVLIDEPDDKIDSEVARHILRVRRGESEVV------ 234 Query: 590 NGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPIT 649 +I E +++YI Y R P +S +A E++ +V +RK + + E IPIT Sbjct: 235 -APKIPHEILRKYIAYARKNIHPVISEEAMEEIEKYYVRMRKSVKKTKGEEEGIPPIPIT 293 Query: 650 IRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQ 694 RQLEA+IR++E+ A++ LSPI EAI+L + + A Sbjct: 294 ARQLEALIRLSEAHARMRLSPIVTREDAREAIKLMEYTLKQIAMD 338 >3F8T-A nrPDB Length = 506 Score = 340 bits (871), Expect = 2e-93, Method: Composition-based stats. Identities = 98/350 (28%), Positives = 158/350 (45%), Gaps = 45/350 (12%) Query: 351 EEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDI 410 E EEF +L+ L +IAP + G E++ K + L K + RL Sbjct: 190 PAELEEFRELADKDPLT-TFARAIAP-LPGAEEVGKMLALQLFSCVGK---NSERL---- 240 Query: 411 NVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMV 470 +VLL G P L ++ ++P VY + + LTA ++ D R + L GA V Sbjct: 241 HVLLAGYPVVCSEILHHVLDHLAPRGVYVDLRRTELTDLTAVLKED---RGWALRAGAAV 297 Query: 471 LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRY 530 LADGG++ +D + + R A+ EAM++ T+++ GI LN+R +VLAA NP G Sbjct: 298 LADGGILAVDHLEGAPEPHRWALMEAMDKGTVTV--DGIA--LNARCAVLAAINP--GEQ 351 Query: 531 DDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEEN 590 P ID LS FD+I + + + EE Sbjct: 352 WPSDPPIARIDLDQDFLSHFDLIAFL----------------------GVDPRPGEPEEQ 389 Query: 591 GSEIS-IEKMKRYITYC-RLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSIPI 648 +E+ ++RY+ Y R AP L+ +A ++L + T + + E ++P+ Sbjct: 390 DTEVPSYTLLRRYLLYAIREHPAPELTEEARKRLEHWYETR--REEVEERLGMGLPTLPV 447 Query: 649 TIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIG 698 T RQLE++ R+ ++ A++ LS + VD A L ++ A Q P G Sbjct: 448 TRRQLESVERLAKAHARMRLSDDVEPEDVDIAAELVD-WYLETAMQIPGG 496 >4QHS-A nrPDB Length = 267 Score = 41.4 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 42/229 (18%), Positives = 85/229 (37%), Gaps = 30/229 (13%) Query: 383 DIKKAIVCLLMGGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPI--AVYTS 440 D K + L K D NV++LG G+ K + +++ SP + + Sbjct: 21 DTKSLKLLALADKVAKT---------DANVMILGPSGSGKEVMSRYIHNASPRKEGPFIA 71 Query: 441 GKGSSAAG--LTASV---QRDPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHE 495 ++ L A++ ++ T G A GG + +DE +M + + Sbjct: 72 INCAAIPDNMLEATLFGYEKGAFTGAVQACPGKFEQAQGGTILLDEISEMDLNLQAKLLR 131 Query: 496 AMEQQTISIAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFI 555 ++++ + + + L+ R VLA +N +Y F+ + R ++ + Sbjct: 132 VLQEREVERLGSRKSIKLDVR--VLATSNRDLKQY------VQAGHFREDLYYRLNVFPL 183 Query: 556 VKDDHNEERD--ISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRY 602 E +D +ANH+I H + + +I K+ Y Sbjct: 184 TWPALCERKDDIEPLANHLIERHC----KKLGLPVPSIAPNAITKLLNY 228 >5EXS-A nrPDB Length = 260 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 48/125 (38%), Gaps = 17/125 (13%) Query: 409 DINVLLLGDPGTAKSQLLKFVEKVSPI-----------AVYTSGKGSSAAGLTASVQRDP 457 D +VL+LG+ GT K + + + S A+ S G ++ Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 458 MTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRT 517 T G LA+GG + +DE M +V + ++++T + G N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 518 SVLAA 522 ++AA Sbjct: 147 RIIAA 151 >2R44-A nrPDB Length = 331 Score = 39.8 bits (91), Expect = 0.005, Method: Composition-based stats. Identities = 44/275 (16%), Positives = 93/275 (33%), Gaps = 32/275 (11%) Query: 411 NVLLLGDPGTAKSQLLKFVEKVS----PIAVYTSGKGSSAAGLTASVQRDPMTREFYLEG 466 ++LL G PG AK+ + + K +T S L ++ + F ++ Sbjct: 48 HILLEGVPGLAKTLSVNTLAKTMDLDFHRIQFTPDLLPS--DLIGTMIYNQHKGNFEVKK 105 Query: 467 GAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPI 526 G + + DE ++ + + A+ E M+++ ++I T L++ VLA NP+ Sbjct: 106 GPVF---SNFILADEVNRSPAKVQSALLECMQEKQVTIGDT--TYPLDNPFLVLATQNPV 160 Query: 527 YGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQ 586 + + RF M+ I ++E ++ + V N++ N + Sbjct: 161 --EQEGTYP------LPEAQVDRF-MMKIHLTYLDKESELEVMRRVSNMNF-NYQVQKIV 210 Query: 587 QEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTERSSI 646 + + EI E K +S + + R Sbjct: 211 SKNDVLEIRNEINKV-----------TISESLEKYIIELVFATRFPAEYGLEAEASYILY 259 Query: 647 PITIRQLEAIIRITESLAKLELSPIAQERHVDEAI 681 + R + R+ +++A + E Sbjct: 260 GASTRAAINLNRVAKAMAFFNNRDYVLPEDIKEVA 294 >5EXX-A nrPDB Length = 343 Score = 39.5 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 27/125 (21%), Positives = 48/125 (38%), Gaps = 17/125 (13%) Query: 409 DINVLLLGDPGTAKSQLLKFVEKVSPI-----------AVYTSGKGSSAAGLTASVQRDP 457 D +VL+LG+ GT K + + + S A+ S G ++ Sbjct: 33 DASVLILGESGTGKEVVARNLHYHSKRREGPFVPVNCGAIPAELLESELFGH----EKGA 88 Query: 458 MTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRT 517 T G LA+GG + +DE M +V + ++++T + G N Sbjct: 89 FTGAITSRAGRFELANGGTLFLDEIGDMPLPMQVKLLRVLQERT--FERVGSNKTQNVDV 146 Query: 518 SVLAA 522 ++AA Sbjct: 147 RIIAA 151 >3DZD-A nrPDB Length = 368 Score = 38.7 bits (88), Expect = 0.009, Method: Composition-based stats. Identities = 24/119 (20%), Positives = 47/119 (39%), Gaps = 8/119 (6%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPI-AVYTSGKGSSAAGLTASVQ-----RDPMTREFYLE 465 VL+ G+ GT K + + + + S + +S A + + T + Sbjct: 155 VLITGESGTGKEIVARLIHRYSGRKGAFVDLNCASIPQELAESELFGHEKGAFTGALTRK 214 Query: 466 GGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAAN 524 G + LAD G + +DE ++ + + +E T S + G + V++A N Sbjct: 215 KGKLELADQGTLFLDEVGELDQRVQAKLLRVLE--TGSFTRLGGNQKIEVDIRVISATN 271 >6ED3-A nrPDB Length = 848 Score = 38.3 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 69/383 (18%), Positives = 131/383 (34%), Gaps = 61/383 (15%) Query: 380 GNEDIKKAIVCLLMGG-SKKILPDGMRLRGDINVLLLG--DPGTAKSQLLKFVEKVSPIA 436 G I + + ++ G + L D + D+ ++ G G + +L ++ + A Sbjct: 211 GKTAIVEGLAQRIVAGDVPESLRDKTIVALDLGSMVAGSKYRGEFEERLKAVLDDIKNSA 270 Query: 437 VYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMV---LADG-----GVVCIDEFDKMRDE 488 G+ + ++ T E ++ G M+ LA G G +DE+ K ++ Sbjct: 271 ----GQIITFIDELHTIVGAGATGEGAMDAGNMIKPMLARGELRLVGATTLDEYRKHIEK 326 Query: 489 D--------RVAIHEAMEQQTISIAKA-----GITTVLNSRTSVLAAANPIYGRYDDLK- 534 D +V + E + TI I + + + S L AA + RY + Sbjct: 327 DAALERRFQQVYVGEPSVEDTIGILRGLKDRYEVHHGVRITDSALVAAATLSDRYITARF 386 Query: 535 SPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEI 594 P ID SR M D E D + V + + + E + + Sbjct: 387 LPDKAIDLVDEAASRLRM---EIDSRPVEID-EVERLVRRLEIEEMALSKEEDEASAERL 442 Query: 595 SIEKMKRYITYCRLKCAPRLSPQAAEK--------LSSNFVTIRKQLLINELE------- 639 + K++ + + K A + EK L +R + E + Sbjct: 443 A--KLRSELADQKEKLAELTTRWQNEKNAIEIVRDLKEQLEALRGESERAERDGDLAKAA 500 Query: 640 STERSSIPITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGG 699 IP ++L+A + ++ ++ L + A + A + P G Sbjct: 501 ELRYGRIPEVEKKLDAALPQAQAREQVMLKEEVGPDDI--------ADVVSAWTGIPAGR 552 Query: 700 LNQASGTSLSEIRRFEQELKRRL 722 L + L R E EL +R+ Sbjct: 553 LLEGETAKLL---RMEDELGKRV 572 Score = 29.4 bits (64), Expect = 5.7, Method: Composition-based stats. Identities = 16/63 (25%), Positives = 26/63 (41%), Gaps = 1/63 (1%) Query: 659 ITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQEL 718 + E+ K+ S + + Q + D ++ G L+ G +EIRR Q L Sbjct: 136 LREAFVKVRGSARVTSPEPEATYQALQKYSTDLTARAREGKLDPVIGRD-NEIRRVVQVL 194 Query: 719 KRR 721 RR Sbjct: 195 SRR 197 >1OFI-A nrPDB Length = 310 Score = 36.4 bits (82), Expect = 0.048, Method: Composition-based stats. Identities = 26/122 (21%), Positives = 55/122 (45%), Gaps = 8/122 (6%) Query: 370 LTNSIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDI---NVLLLGDPGTAKSQLL 426 + + + I G D K+A+ L + + LR ++ N+L++G G K+++ Sbjct: 9 IVSELDQHIIGQADAKRAVAIALRN-RWRRMQLQEPLRHEVTPKNILMIGPTGVGKTEIA 67 Query: 427 KFVEKVSPIAVYTSGKGSSAAGLTASVQR-DPMTREFYLEGGAMVLA--DGGVVCIDEFD 483 + + K++ A + + + + + D + R+ G + A G+V IDE D Sbjct: 68 RRLAKLA-NAPFIKVEATKFTEVGYVGKEVDSIIRDLTDSAGGAIDAVEQNGIVFIDEID 126 Query: 484 KM 485 K+ Sbjct: 127 KI 128 >1NY5-A nrPDB Length = 387 Score = 35.2 bits (79), Expect = 0.096, Method: Composition-based stats. Identities = 44/208 (21%), Positives = 76/208 (36%), Gaps = 31/208 (14%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY-LEGGAMV 470 VL+ G+ G K + + + K+S + K A AS+ RD E + E GA Sbjct: 163 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 217 Query: 471 -----------LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSV 519 LADGG + +DE ++ E + + +E + G + + Sbjct: 218 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 275 Query: 520 LAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDI--SIANHVINIHT 577 LAA N +K F+ + R +I I E ++ +ANH + + Sbjct: 276 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 329 Query: 578 GNANAMQNQQEENGSEISIEKMKRYITY 605 E ++ + E + Y Y Sbjct: 330 RKYAKEV----EGFTKSAQELLLSYPWY 353 >4LZZ-A nrPDB Length = 268 Score = 35.2 bits (79), Expect = 0.10, Method: Composition-based stats. Identities = 44/208 (21%), Positives = 76/208 (36%), Gaps = 31/208 (14%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY-LEGGAMV 470 VL+ G+ G K + + + K+S + K A AS+ RD E + E GA Sbjct: 44 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 98 Query: 471 -----------LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSV 519 LADGG + +DE ++ E + + +E + G + + Sbjct: 99 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 156 Query: 520 LAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDI--SIANHVINIHT 577 LAA N +K F+ + R +I I E ++ +ANH + + Sbjct: 157 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 210 Query: 578 GNANAMQNQQEENGSEISIEKMKRYITY 605 E ++ + E + Y Y Sbjct: 211 RKYAKEV----EGFTKSAQELLLSYPWY 234 >4M9Z-A nrPDB Length = 549 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 33/229 (14%), Positives = 76/229 (33%), Gaps = 11/229 (4%) Query: 14 LQGESPNDDDNTEIIKSFKNFILEFRLDSQFIYRDQLRNNILVKNYSLTVNMEHLIGYNE 73 L+G++ +D++E+I + E + IYR Q + ++ N HL + E Sbjct: 30 LEGKNIFTEDHSELISKMSTRL-ERIANFLRIYRRQASELGPLIDFFNYNNQSHLADFLE 88 Query: 74 DIYKKLSDEPSDIIPL-----FETAITQVAKRISILSRAQSANNNDKDPENTSMDTDSLL 128 D +EP + P+ F + + + + + + + D + Sbjct: 89 DYIDFAINEPDLLRPVVIAPQFSRQMLDRKLLLGNVPKQMTCYIREYHVDRVIKKLDEMC 148 Query: 129 LNS--LPTFQLILNSNANQIPLRDLDSEHVSKIVRLSGII-ISTSVLSSRATYLSIMCRN 185 S + I + L + I+ + S + ++T+ Sbjct: 149 DLDSFFLFLHGRAGSGKSVIASQALSKSDQLIGINYDSIVWLKDSGTAPKSTFDLFTDIL 208 Query: 186 CRHTTSITINNFN--SITGNTVSLPRSCLSTIESESSMANESNIGDEST 232 + + NF + V C + I+ +++ ++ E T Sbjct: 209 LMLKSEDDLLNFPSVEHVTSVVLKRMICNALIDRPNTLFVFDDVVQEET 257 >1IN6-A nrPDB Length = 334 Score = 34.5 bits (77), Expect = 0.18, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 58/152 (38%), Gaps = 30/152 (19%) Query: 360 LSRNPKLYEILTNSIAP----SIFGNEDIKKAIVCLLMGGSKKILPDGMRLRGDI--NVL 413 L+ +Y+ + P G E++KK + L + ++RG++ +VL Sbjct: 5 LTPERTVYDSGVQFLRPKSLDEFIGQENVKKKLSLAL---------EAAKMRGEVLDHVL 55 Query: 414 LLGDPGTAKSQLLKFVEKVSPIAVY-TSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLA 472 L G PG ++ L + ++ TSG G A++ L Sbjct: 56 LAGPPGLGRTTLAHIIASELQTNIHVTSGPVLVKQGDMAAILTS--------------LE 101 Query: 473 DGGVVCIDEFDKMRDEDRVAIHEAMEQQTISI 504 G V+ IDE ++ ++ A+E I I Sbjct: 102 RGDVLFIDEIHRLNKAVEELLYSAIEDFQIDI 133 >4BS1-B nrPDB Length = 173 Score = 34.1 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 31/125 (24%), Positives = 50/125 (40%), Gaps = 19/125 (15%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY-LEGGAMV 470 VL+ G+ G K + + + K+S + K A AS+ RD E + E GA Sbjct: 27 VLITGESGVGKEVVARLIHKLSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 81 Query: 471 -----------LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSV 519 LADGG + +DE ++ E + + +E + G + + Sbjct: 82 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 139 Query: 520 LAAAN 524 LAA N Sbjct: 140 LAATN 144 >4L4U-A nrPDB Length = 447 Score = 34.1 bits (76), Expect = 0.25, Method: Composition-based stats. Identities = 44/208 (21%), Positives = 75/208 (36%), Gaps = 31/208 (14%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFY-LEGGAMV 470 VL+ G+ G K + + + K S + K A AS+ RD E + E GA Sbjct: 171 VLITGESGVGKEVVARLIHKSSDRS-----KEPFVALNVASIPRDIFEAELFGYEKGAFT 225 Query: 471 -----------LADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSV 519 LADGG + +DE ++ E + + +E + G + + Sbjct: 226 GAVSSKEGFFELADGGTLFLDEIGELSLEAQAKLLRVIESG--KFYRLGGRKEIEVNVRI 283 Query: 520 LAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDI--SIANHVINIHT 577 LAA N +K F+ + R +I I E ++ +ANH + + Sbjct: 284 LAATNRN------IKELVKEGKFREDLYYRLGVIEIEIPPLRERKEDIIPLANHFLKKFS 337 Query: 578 GNANAMQNQQEENGSEISIEKMKRYITY 605 E ++ + E + Y Y Sbjct: 338 RKYAKEV----EGFTKSAQELLLSYPWY 361 >5W0T-A nrPDB Length = 304 Score = 33.7 bits (75), Expect = 0.28, Method: Composition-based stats. Identities = 58/294 (19%), Positives = 101/294 (34%), Gaps = 44/294 (14%) Query: 334 QSDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLM 393 + V+ S VT+ + E L P I I D+ ++++ LM Sbjct: 6 EKLVKRSPALAEVTL--DAYERTILSSIVTPDEINITFQDIGGLDPLISDLHESVIYPLM 63 Query: 394 GGSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASV 453 ++ + L+ VLL G PG K+ L K + K S A + S + SS Sbjct: 64 --MPEVYSNSPLLQAPSGVLLYGPPGCGKTMLAKALAKESG-ANFISIRMSSIMD----- 115 Query: 454 QRDPMTREFYLEGGAMV-----LADG---GVVCIDEFDKMRDEDRVAIHEAME--QQTIS 503 ++Y E +V LA+ ++ IDE D E HE + Sbjct: 116 -------KWYGESNKIVDAMFSLANKLQPCIIFIDEIDSFLRERSSTDHEVTATLKAEFM 168 Query: 504 IAKAGITTVLNSRTSVLAAANPIYGRYDDLKSPGDNIDFQTTIL-------SRFDMIFIV 556 G+ N R ++ A N R +D+ L R+ ++ ++ Sbjct: 169 TLWDGLLN--NGRVMIIGATN----RINDIDDAFLR-RLPKRFLVSLPGSDQRYKILSVL 221 Query: 557 KDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKC 610 D + D + + G + + +E E +++ K YI R Sbjct: 222 LKDTKLDEDEFDLQLIADNTKGFSG---SDLKELCREAALDAAKEYIKQKRQLI 272 >4FQJ-A nrPDB Length = 304 Score = 33.7 bits (75), Expect = 0.28, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 35/104 (33%) Query: 195 NNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQ 254 NN N+ TV +P C + + S+ + +P ++ Sbjct: 134 NNKNATNPLTVEVPYICTEGEDQITVWGFHSDDKTQMKNLYGDSNPQKFTSSANGVTTHY 193 Query: 255 FLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY 298 ++ P+ G +P++ + D + GT V G+ Sbjct: 194 VSQIGSFPDQTEDGGLPQSGRIVVDYMMQKPGKTGTIVYQRGVL 237 >3M6A-A nrPDB Length = 543 Score = 32.9 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 66/393 (16%), Positives = 130/393 (33%), Gaps = 57/393 (14%) Query: 335 SDVETSSIWNSVTMFTEEEEEEFLQLSRNPKLYEILTNSIAPSIFGNEDIKKAIVCLLMG 394 S + W +T+E +++ L +L + G E +K+ I+ L Sbjct: 48 SVIRNYIDWLVALPWTDETDDKL-DLKEAGRLLDE-------EHHGLEKVKERILEYL-- 97 Query: 395 GSKKILPDGMRLRGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQ 454 +K+ L+G I + L G PG K+ L K + K + G+ L Sbjct: 98 AVQKLTK---SLKGPI-LCLAGPPGVGKTSLAKSIAK-------SLGRKFVRISLGGVRD 146 Query: 455 RDPMTREFYLEGGAMV------LADGG----VVCIDEFDKMRDEDR----VAIHEAME-Q 499 + GAM + G V +DE DKM + R A+ E ++ + Sbjct: 147 ESEIRGHRRTYVGAMPGRIIQGMKKAGKLNPVFLLDEIDKMSSDFRGDPSSAMLEVLDPE 206 Query: 500 QTISIAKAGITTVLN-SRTSVLAAANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKD 558 Q S + I + S+ +A AN + L+ + I+ + + + IVKD Sbjct: 207 QNSSFSDHYIEETFDLSKVLFIATANNLATIPGPLRDRMEIINIAG--YTEIEKLEIVKD 264 Query: 559 --DHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSP 616 + ++ + + + + S+E ++ CR ++ Sbjct: 265 HLLPKQIKEHGLKKSNLQLRDQAILDIIRYYTREAGVRSLE--RQLAAICRKAAKAIVAE 322 Query: 617 QAA-----EKLSSNFVTIR------KQLLINELESTERSSIPITIRQLEAIIRITESLAK 665 + EK +F+ R + T + + L + ++ K Sbjct: 323 ERKRITVTEKNLQDFIGKRIFRYGQAETEDQVGVVTGLAYTTVGGDTLSIEVSLSPGKGK 382 Query: 666 LELS---PIAQERHVDEAIRLFQASTMDAASQD 695 L L+ A ++ T + + Sbjct: 383 LILTGKLGDVMRESAQAAFSYVRSKTEELGIEP 415 >4YPL-A nrPDB Length = 555 Score = 32.5 bits (72), Expect = 0.64, Method: Composition-based stats. Identities = 38/242 (15%), Positives = 81/242 (33%), Gaps = 36/242 (14%) Query: 379 FGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVL-LLGDPGTAKSQLLKFVEKVSPIAV 437 +G +D+K+ I+ L + + L G+ +R +L L+G PG K+ L + + + Sbjct: 82 YGLKDVKERILEYL---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 138 Query: 438 YTSGKGSSAAGLTASVQRDPMT-----REFYLEGGAMVLADGGVVCIDEFDKMRDEDR-- 490 + G A ++ T + V V+ +D+ DKM + R Sbjct: 139 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDQIDKMSSDWRGD 196 Query: 491 --VAIHEAME-QQTISIAKAGITTVLN-SRTSVLAAANPIYGRYDDLKSPGDNIDFQTTI 546 A+ E ++ +Q + + + S+ + AN + + Sbjct: 197 PASAMLEVLDPEQNNTFTDHYLDVPYDLSKVFFITTANTLQ-------------TIPRPL 243 Query: 547 LSRFDMIFIVKDDHNEERDISIANHVINIHTGNANAMQNQQEENGSEISIEKMKRYITYC 606 L R ++I + A + + ++ E ++ Y Sbjct: 244 LDRMEVI----EIPGYTNMEKQA--IARQYLWPKQVRESGMEGRIEVTDAAILRVISEYT 297 Query: 607 RL 608 R Sbjct: 298 RE 299 >4I5O-A nrPDB Length = 363 Score = 32.5 bits (72), Expect = 0.73, Method: Composition-based stats. Identities = 35/168 (20%), Positives = 65/168 (38%), Gaps = 23/168 (13%) Query: 378 IFGNEDIKKAIVCLLMGGSKKILPDGMR---LRGDINVLLLGDPGTAKSQLLKFVEKV-- 432 + G E KK + + K++ G N+LL+G G+ K+ L + + ++ Sbjct: 17 VIGQEQAKKVLAVAVYNHYKRLRNGDTSNGVELGKSNILLIGPTGSGKTLLAETLARLLD 76 Query: 433 ----SPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVLADGGVVCIDEFDKM-RD 487 A + G + +Q+ ++ ++ A G+V IDE DK+ R Sbjct: 77 VPFTMADATTLTEAGYVGEDVENIIQKLLQKCDYDVQK-----AQRGIVYIDEIDKISRK 131 Query: 488 EDRVAIHEAMEQQTISIAKAGI-TTVLNSRTSVLAAANPIYGRYDDLK 534 D +I T ++ G+ +L +AA P GR + Sbjct: 132 SDNPSI-------TRDVSGEGVQQALLKLIEGTVAAVPPQGGRKHPQQ 172 >4PA8-A nrPDB Length = 258 Score = 32.5 bits (72), Expect = 0.75, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 28/64 (43%) Query: 648 ITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTS 707 +T R+LE+++ S L I E +D A+R+ + + G +N+ + Sbjct: 137 LTERELESLLEYARSYGMEPLILINDENDLDIALRIGARFIVIFSMNFETGEINKENQRK 196 Query: 708 LSEI 711 L + Sbjct: 197 LISM 200 >1OJL-A nrPDB Length = 304 Score = 32.5 bits (72), Expect = 0.80, Method: Composition-based stats. Identities = 31/208 (14%), Positives = 74/208 (35%), Gaps = 31/208 (14%) Query: 409 DINVLLLGDPGTAKSQLLKFVEKVSPI-----------AVYTSGKGSSAAGLTASVQRDP 457 D VL+ GD GT K + + + S A+ S S G ++ Sbjct: 25 DATVLIHGDSGTGKELVARALHACSARSDRPLVTLNCAALNESLLESELFGH----EKGA 80 Query: 458 MTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRT 517 T G V ADGG + +DE + +V + A++++ + + G ++ Sbjct: 81 FTGADKRREGRFVEADGGTLFLDEIGDISPLMQVRLLRAIQER--EVQRVGSNQTISVDV 138 Query: 518 SVLAAANPIYGRYDDLKSPGDNID---FQTTILSRFDMIFIVKDDHNEERDISIANHVIN 574 ++AA + + + + F+ + R +++ I + + + + + Sbjct: 139 RLIAATH---------RDLAEEVSAGRFRQDLYYRLNVVAI--EMPSLRQRREDIPLLAD 187 Query: 575 IHTGNANAMQNQQEENGSEISIEKMKRY 602 + + + +++ + Y Sbjct: 188 HFLRRFAERNRKVVKGFTPQAMDLLIHY 215 >5C3C-A nrPDB Length = 281 Score = 32.1 bits (71), Expect = 0.83, Method: Composition-based stats. Identities = 40/214 (18%), Positives = 77/214 (35%), Gaps = 27/214 (12%) Query: 410 INVLLLGDPGTAKSQLLKFVEKVS-----PIAVYTSGKGSSAAGLTASVQRDPMTREFYL 464 I ++L G G KS +FVE ++ P+ + +A+ L D + Sbjct: 48 IPMMLKGPTGCGKS---RFVEHMAWKLNRPLITIACNEDMTASDLVGRYLLDKDGTRW-- 102 Query: 465 EGGAMVLAD--GGVVCIDEFDKMRDEDRVAIHEAMEQQTI-SIAKAGITTVLNSRTSVLA 521 + G + +A G + +DE + R + V IH + + + + K G + ++ Sbjct: 103 QDGPLTVAARIGAICYLDEIVEARQDTIVVIHPLTDHRRVLPLEKKGELVEAHPDFQIVI 162 Query: 522 AANPIYGRYDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTGNAN 581 + NP G +K D + + RF + D + + I +H + A Sbjct: 163 SYNP--GYQSLMK------DLKQSTKQRFGALDF--DYPKPDIEAEIVSHEAGVDKDTAE 212 Query: 582 AM----QNQQEENGSEISIEKMKRYITYCRLKCA 611 + Q + G + R + Y A Sbjct: 213 KLVQIAQKARNLKGHGLDEGLSTRLLVYAGKLIA 246 >1QVR-A nrPDB Length = 854 Score = 32.1 bits (71), Expect = 0.89, Method: Composition-based stats. Identities = 62/344 (18%), Positives = 122/344 (35%), Gaps = 58/344 (16%) Query: 407 RGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEG 466 R N +L+G+PG K+ + VE ++ V KG GL R L+ Sbjct: 189 RTKNNPVLIGEPGVGKTAI---VEGLAQRIV----KGDVPEGL-------KGKRIVSLQM 234 Query: 467 GAMVLADGGVVCIDEFDKMRDEDRVAIHEAME-QQTISIAKAGITTVLNSRTS--VLAAA 523 G+++ G EF+ + + I E ++ Q + + + TV+ + + + A Sbjct: 235 GSLL---AGAKYRGEFE---ERLKAVIQEVVQSQGEVILFIDELHTVVGAGKAEGAVDAG 288 Query: 524 N---PIYGRYD------DLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVIN 574 N P R + I+ + RF +++ D+ E IS ++ Sbjct: 289 NMLKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYV--DEPTVEETIS----ILR 342 Query: 575 IHTGNANAMQNQQEENGSEISIEKMK-RYI---------------TYCRLKCAPRLSPQA 618 + + + I+ + RYI RL+ A +P+ Sbjct: 343 GLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAPEE 402 Query: 619 AEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQER--- 675 + L + + + + E S + + E I ++TE +AKL + Sbjct: 403 IDALERKKLQLEIEREALKKEKDPDSQERLKAIEAE-IAKLTEEIAKLRAEWEREREILR 461 Query: 676 HVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELK 719 + EA + + LN+A+ E+ + E E++ Sbjct: 462 KLREAQHRLDEVRREIELAERQYDLNRAAELRYGELPKLEAEVE 505 >1HQC-A nrPDB Length = 324 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 39/209 (18%), Positives = 74/209 (35%), Gaps = 25/209 (11%) Query: 411 NVLLLGDPGTAKSQLLKFVEK-VSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAM 469 ++LL G PG K+ L + + TSG G A++ A Sbjct: 40 HLLLFGPPGLGKTTLAHVIAHELGVNLRVTSGPAIEKPGDLAAIL-------------AN 86 Query: 470 VLADGGVVCIDEFDKMRDEDRVAIHEAMEQQTISIAKAGITTVLNSRTSVLAAANPIYGR 529 L +G ++ IDE ++ + ++ AME + I I +RT L P + Sbjct: 87 SLEEGDILFIDEIHRLSRQAEEHLYPAMEDFVMDIV---IGQGPAARTIRLEL--PRFTL 141 Query: 530 YDDLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISI---ANHVINIHTGNANAMQNQ 586 PG +LSRF ++ ++ EE + A + T A + Sbjct: 142 IGATTRPGL---ITAPLLSRFGIVEHLEYYTPEELAQGVMRDARLLGVRITEEAALEIGR 198 Query: 587 QEENGSEISIEKMKRYITYCRLKCAPRLS 615 + ++ +R + ++ ++ Sbjct: 199 RSRGTMRVAKRLFRRVRDFAQVAGEEVIT 227 >1MKY-A nrPDB Length = 439 Score = 32.1 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 12/138 (8%), Positives = 41/138 (29%), Gaps = 1/138 (0%) Query: 238 PDPYIIIHESSKFIDQQFLKLQEIPELVPVGEM-PRNLTMTCDRYLTNKVIPGTRVTIVG 296 P + FID + + L + PR + + + + + V IV Sbjct: 212 PGTTRDPVDDEVFIDGRKYVFVDTAGLRRKSRVEPRTVEKYSNYRVVDSIEKADVVVIVL 271 Query: 297 IYSIYNSKNGAGSGRSGGGNGGSGVAIRTPYIKILGIQSDVETSSIWNSVTMFTEEEEEE 356 + ++ G + V + + ++ + + + ++ + Sbjct: 272 DATQGITRQDQRMAGLMERRGRASVVVFNKWDLVVHREKRYDEFTKLFREKLYFIDYSPL 331 Query: 357 FLQLSRNPKLYEILTNSI 374 + + + +++ Sbjct: 332 IFTSADKGWNIDRMIDAM 349 >4M44-A nrPDB Length = 346 Score = 31.8 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 17/104 (16%), Positives = 34/104 (32%) Query: 195 NNFNSITGNTVSLPRSCLSTIESESSMANESNIGDESTKKNCGPDPYIIIHESSKFIDQQ 254 NN + TV +P C + + S+ + +P ++ Sbjct: 164 NNKTATNPLTVEVPHICTKEEDQITVWGFHSDDKTQMKNLYGDSNPQKFTSSANGVTTHY 223 Query: 255 FLKLQEIPELVPVGEMPRNLTMTCDRYLTNKVIPGTRVTIVGIY 298 ++ P+ G +P++ + D + GT V GI Sbjct: 224 VSQIGGFPDQTEDGGLPQSGRIVVDYMVQKPGKTGTIVYQRGIL 267 >5AOU-A nrPDB Length = 258 Score = 31.8 bits (70), Expect = 1.1, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 26/64 (40%) Query: 648 ITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTS 707 +T R+LE+++ L I E +D A+R+ + G +N+ + Sbjct: 137 LTERELESLLEYARGYGMEPLILINDENDLDIALRIGARFITIYSMNFETGEINKENQRK 196 Query: 708 LSEI 711 L + Sbjct: 197 LISM 200 >4YPN-A nrPDB Length = 293 Score = 31.8 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 53/130 (40%), Gaps = 15/130 (11%) Query: 379 FGNEDIKKAIVCLLMGGSKKILPDGMRLRGDINVL-LLGDPGTAKSQLLKFVEKVSPIAV 437 +G +D+K+ I+ L + + L G+ +R +L L+G PG K+ L + + + Sbjct: 115 YGLKDVKERILEYL---AVRQLTQGLDVRNKAPILVLVGPPGVGKTSLGRSIARSMNRKF 171 Query: 438 YTSGKGSSAAGLTASVQRDPMT-----REFYLEGGAMVLADGGVVCIDEFDKMRDEDR-- 490 + G A ++ T + V V+ +DE DKM + R Sbjct: 172 HRISLG--GVRDEAEIRGHRRTYIGAMPGKLIHAMKQVGVINPVILLDEIDKMSSDWRGD 229 Query: 491 --VAIHEAME 498 A+ E ++ Sbjct: 230 PASAMLEVLD 239 >4PEK-A nrPDB Length = 258 Score = 31.8 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 16/64 (25%), Positives = 28/64 (43%) Query: 648 ITIRQLEAIIRITESLAKLELSPIAQERHVDEAIRLFQASTMDAASQDPIGGLNQASGTS 707 +T R+LE+++ S L I E +D A+R+ AA G +N+ + Sbjct: 137 LTERELESLLEYARSYGMEPLIIINDENDLDIALRIGARFIGIAARDWETGEINKENQRK 196 Query: 708 LSEI 711 L + Sbjct: 197 LISM 200 >3U5Z-B nrPDB Length = 324 Score = 31.8 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 28/122 (22%), Positives = 39/122 (31%), Gaps = 15/122 (12%) Query: 412 VLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEGGAMVL 471 +L PGT K+ + K + V + + R P+T A Sbjct: 51 ILHSPSPGTGKTTVAKALCH----DVNADMMFVNGSDCKIDFVRGPLTN---FASAASFD 103 Query: 472 ADGGVVCIDEFDKM----RDEDRVAIHEAMEQQTISIAKA----GITTVLNSRTSVLAAA 523 V+ IDEFD+ + EA I A GI L SR V+ Sbjct: 104 GRQKVIVIDEFDRSGLAESQRHLRSFMEAYSSNCSIIITANNIDGIIKPLQSRCRVITFG 163 Query: 524 NP 525 P Sbjct: 164 QP 165 >1UM8-A nrPDB Length = 376 Score = 31.4 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 31/132 (23%), Positives = 51/132 (38%), Gaps = 12/132 (9%) Query: 411 NVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGS-SAAGLTASVQRDPMTREFYLEGGAM 469 N+LL+G G+ K+ + + + K I + S S + AG + +TR + Sbjct: 74 NILLIGPTGSGKTLMAQTLAKHLDIPIAISDATSLTEAGYVGEDVENILTRLLQASDWNV 133 Query: 470 VLADGGVVCIDEFDKMR--DEDRVAIHEAMEQQTISIAKAGI-TTVLNSRTSVLAAANPI 526 A G+V IDE DK+ E+R T ++ G+ +L L P Sbjct: 134 QKAQKGIVFIDEIDKISRLSENRSI--------TRDVSGEGVQQALLKIVEGSLVNIPPK 185 Query: 527 YGRYDDLKSPGD 538 GR + Sbjct: 186 GGRKHPEGNFIQ 197 >4BL8-A nrPDB Length = 831 Score = 30.6 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 15/74 (20%), Positives = 29/74 (39%) Query: 583 MQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSSNFVTIRKQLLINELESTE 642 + +E E ++R + P ++PQ L+ + RK L ++ + Sbjct: 636 QPRRLSGKDTEQIRETLRRGLEINSKPVLPPINPQRQNGLAHDRAPSRKDSLESDSSTAI 695 Query: 643 RSSIPITIRQLEAI 656 I RQLE++ Sbjct: 696 IPHELIRTRQLESV 709 >3KC2-A nrPDB Length = 352 Score = 30.6 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 21/106 (19%), Positives = 36/106 (33%), Gaps = 11/106 (10%) Query: 529 RYDDLKSPGDNI----------DFQTTILSRFDMIFIVKDDHNEERDISIANHVINIHTG 578 RY+ +P + D +FD + + D H+ DI I + IN G Sbjct: 124 RYNRDIAPFSGLSDEQVMEYSRDIPDLTTKKFDAVLVFNDPHDWAADIQIISDAINSENG 183 Query: 579 NANAMQNQQEENGSEISIEKMKRYITYCRLKCAPRLSPQAAEKLSS 624 N ++N++ I I + + + R A L Sbjct: 184 MLNTLRNEKSGK-PSIPIYFSNQDLLWANPYKLNRFGQGAFRLLVR 228 >2D2N-C nrPDB Length = 147 Score = 30.6 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 15/73 (20%), Positives = 25/73 (34%), Gaps = 9/73 (12%) Query: 373 SIAPSIFGNEDIKKAIVCLLMGGSKKILPDGMRLRG---------DINVLLLGDPGTAKS 423 ++A ++F + + A L G PD R D+ + +L DP Sbjct: 30 ALAQAVFASLFSRDAAAQGLFSGVSADNPDSADFRAHCVRVVNGLDVAINMLNDPAVLNE 89 Query: 424 QLLKFVEKVSPIA 436 QL + A Sbjct: 90 QLAHLSAQHQARA 102 >4ZPX-A nrPDB Length = 413 Score = 30.2 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 11/24 (45%), Positives = 18/24 (75%) Query: 411 NVLLLGDPGTAKSQLLKFVEKVSP 434 +VLL+G+PGT KS L + + ++ P Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >4QMD-A nrPDB Length = 193 Score = 30.2 bits (66), Expect = 3.9, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 42/93 (45%), Gaps = 13/93 (13%) Query: 436 AVYTSGKGSSAAGLTASVQR--DPMTREFYLEGGAMVLADGGVVCIDEFDKMRDEDRVAI 493 +Y + + + TA + DP+T + LE A A GG+V + +R ++ Sbjct: 8 GIYDTTTDNKCSIKTAVAKNMLDPITGQKLLEAQA---ATGGIV------DLLSRERYSV 58 Query: 494 HEAMEQQTISIAKAGITTVLNSRTSVLAAANPI 526 H+AME+ I +LN++ + +P+ Sbjct: 59 HKAMERGL--IENTSTQRLLNAQKAFTGIEDPV 89 >4F8X-A nrPDB Length = 335 Score = 29.8 bits (65), Expect = 4.2, Method: Composition-based stats. Identities = 12/53 (22%), Positives = 24/53 (45%), Gaps = 3/53 (5%) Query: 417 DPGTAKSQLLKFVEKVSPIAVYTSGKGSSA---AGLTASVQRDPMTREFYLEG 466 +PGT + +L+ V + + G G + G T S+ T++ Y++ Sbjct: 185 NPGTKSTAVLQLVSNLRKRGIRIDGVGLESHFIVGETPSLADQLATKQAYIKA 237 >3K1J-A nrPDB Length = 604 Score = 29.8 bits (65), Expect = 4.5, Method: Composition-based stats. Identities = 11/24 (45%), Positives = 18/24 (75%) Query: 411 NVLLLGDPGTAKSQLLKFVEKVSP 434 +VLL+G+PGT KS L + + ++ P Sbjct: 62 HVLLIGEPGTGKSMLGQAMAELLP 85 >4NMI-A nrPDB Length = 310 Score = 29.4 bits (64), Expect = 6.2, Method: Composition-based stats. Identities = 15/69 (21%), Positives = 30/69 (43%), Gaps = 7/69 (10%) Query: 629 IRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQER---HVDEAIRLFQ 685 ++++ + + ++ + PIT QL++ E L++ E + +AI Q Sbjct: 16 LKRKDPVIYTDRSKDNQAPITKEQLDSY----EKNGFLQIKNFFSEDEVIDMQKAIFELQ 71 Query: 686 ASTMDAASQ 694 S D AS Sbjct: 72 DSIKDVASD 80 >4TMA-B nrPDB Length = 417 Score = 29.1 bits (63), Expect = 7.5, Method: Composition-based stats. Identities = 15/49 (30%), Positives = 23/49 (46%), Gaps = 2/49 (4%) Query: 495 EAMEQQTISIAKAGITTVLNSRTSVLA--AANPIYGRYDDLKSPGDNID 541 EAM+Q ISIA G T N+ LA A + Y+ + + ++ Sbjct: 166 EAMDQYQISIALDGATLHTNASAPALAGEALEKLVSEYNATQKMINRME 214 >4HSE-A nrPDB Length = 397 Score = 29.1 bits (63), Expect = 7.6, Method: Composition-based stats. Identities = 62/344 (18%), Positives = 122/344 (35%), Gaps = 58/344 (16%) Query: 407 RGDINVLLLGDPGTAKSQLLKFVEKVSPIAVYTSGKGSSAAGLTASVQRDPMTREFYLEG 466 R N +L+G+PG K+ + VE ++ V KG GL R L+ Sbjct: 52 RTKNNPVLIGEPGVGKTAI---VEGLAQRIV----KGDVPEGL-------KGKRIVSLQM 97 Query: 467 GAMVLADGGVVCIDEFDKMRDEDRVAIHEAME-QQTISIAKAGITTVLNSRTS--VLAAA 523 G+++ G EF+ + + I E ++ Q + + + TV+ + + + A Sbjct: 98 GSLL---AGAKYRGEFE---ERLKAVIQEVVQSQGEVILFIDELHTVVGAGKAEGAVDAG 151 Query: 524 N---PIYGRYD------DLKSPGDNIDFQTTILSRFDMIFIVKDDHNEERDISIANHVIN 574 N P R + I+ + RF +++ D+ E IS ++ Sbjct: 152 NMLKPALARGELRLIGATTLDEYREIEKDPALERRFQPVYV--DEPTVEETIS----ILR 205 Query: 575 IHTGNANAMQNQQEENGSEISIEKMK-RYI---------------TYCRLKCAPRLSPQA 618 + + + I+ + RYI RL+ A +P+ Sbjct: 206 GLKEKYEVHHGVRISDSAIIAAATLSHRYITERRLPDKAIDLIDEAAARLRMALESAPEE 265 Query: 619 AEKLSSNFVTIRKQLLINELESTERSSIPITIRQLEAIIRITESLAKLELSPIAQER--- 675 + L + + + + E S + + E I ++TE +AKL + Sbjct: 266 IDALERKKLQLEIEREALKKEKDPDSQERLKAIEAE-IAKLTEEIAKLRAEWEREREILR 324 Query: 676 HVDEAIRLFQASTMDAASQDPIGGLNQASGTSLSEIRRFEQELK 719 + EA + + LN+A+ E+ + E E++ Sbjct: 325 KLREAQHRLDEVRREIELAERQYDLNRAAELRYGELPKLEAEVE 368 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.118 0.288 Lambda K H 0.267 0.0365 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 24,181,523 Number of Sequences: 36641 Number of extensions: 903910 Number of successful extensions: 3764 Number of sequences better than 10.0: 63 Number of HSP's better than 10.0 without gapping: 42 Number of HSP's successfully gapped in prelim test: 58 Number of HSP's that attempted gapping in prelim test: 3554 Number of HSP's gapped (non-prelim): 155 length of query: 775 length of database: 10,336,785 effective HSP length: 105 effective length of query: 670 effective length of database: 6,489,480 effective search space: 4347951600 effective search space used: 4347951600 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 63 (29.0 bits)