BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P29401 (623 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4KXX-A nrPDB 1294 0.0 5ND5-A nrPDB 181 1e-45 2R8P-A nrPDB 177 1e-44 4XEU-A nrPDB 175 4e-44 1GPU-A nrPDB 172 3e-43 1ITZ-A nrPDB 163 2e-40 3RIM-A nrPDB 141 1e-33 2O1X-A nrPDB 100 4e-21 2O1S-A nrPDB 96 4e-20 3LQ2-A nrPDB 59 8e-09 1IK6-A nrPDB 51 2e-06 3DV0-B nrPDB 50 2e-06 6CFO-B nrPDB 50 4e-06 1UMC-B nrPDB 44 2e-04 3DVA-A nrPDB 35 0.065 3EXI-A nrPDB 33 0.27 6GUA-A nrPDB 33 0.34 5WWT-A nrPDB 33 0.34 1X7Z-A nrPDB 33 0.38 2J3M-A nrPDB 33 0.42 1O5W-A nrPDB 30 3.8 3AHE-A nrPDB 29 6.5 6O7W-C nrPDB 28 9.0 >4KXX-A nrPDB Length = 637 Score = 1294 bits (3349), Expect = 0.0, Method: Compositional matrix adjust. Identities = 623/623 (100%), Positives = 623/623 (100%) Query: 1 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS 60 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS Sbjct: 1 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS 60 Query: 61 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV 120 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV Sbjct: 61 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV 120 Query: 121 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA Sbjct: 121 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 Query: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA 240 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA Sbjct: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA 240 Query: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN Sbjct: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300 Query: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI 360 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI Sbjct: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI 360 Query: 361 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS 420 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS Sbjct: 361 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS 420 Query: 421 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII Sbjct: 421 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480 Query: 481 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL 540 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL Sbjct: 481 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL 540 Query: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE Sbjct: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600 Query: 601 LLKMFGIDRDAIAQAVRGLITKA 623 LLKMFGIDRDAIAQAVRGLITKA Sbjct: 601 LLKMFGIDRDAIAQAVRGLITKA 623 >5ND5-A nrPDB Length = 692 Score = 181 bits (458), Expect = 1e-45, Method: Compositional matrix adjust. Identities = 166/579 (28%), Positives = 263/579 (45%), Gaps = 70/579 (12%) Query: 20 NRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAA 79 N +R +I A + SGHP A + VL+ M+Y ++P + DRFVLS GH + Sbjct: 34 NAIRFLAIDAINKSKSGHPGMPMGCAPMGYVLWNEVMKYNPKNPDFFNRDRFVLSAGHGS 93 Query: 80 PILYAVWAEAGF--LAEAELLNLRKISSDLDGHPVPKQAFT----DVATGSLGQGLGAAC 133 Y++ G+ + ++ R+ +S GHP + F +V TG LGQG+ A Sbjct: 94 MFQYSMMHLTGYDSVPLDQIKQFRQWNSLTPGHP---ENFVTPGVEVTTGPLGQGICNAV 150 Query: 134 GMA----YTGKYFDK------ASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILD 183 G+A + F+K + YC+LGDG + EG EA + A + L L+A+ D Sbjct: 151 GLAVAEAHLAARFNKPDVKPIVDHYTYCILGDGCMMEGISNEACSLAGHWGLGKLIALYD 210 Query: 184 INRLGQSDPAPLQHQMDIYQKRCEAFGWHAI-IVDGHS-VEELCKAFGQAK---HQPTAI 238 N++ + D+ KR EA GWH I +++G++ V+ L A QAK +PT I Sbjct: 211 DNKISIDGHTDISFTEDV-AKRYEALGWHVIHVINGNTDVDGLRAAIAQAKAVKDKPTLI 269 Query: 239 IAKTFKGRGITGVEDKESWHGKPL-PKNMAE------------QIIQEIYSQIQSKKK-- 283 T G G D HG PL P A ++ Q++Y + K Sbjct: 270 KVSTLIGYGSPNKADSHDVHGAPLGPDETAATRKNLNWPYGEFEVPQDVYDVFRGAIKRG 329 Query: 284 -------------ILATPPQEDAPSVDIANIRMP-----SLPSYKVGDK-IATRKAYGQA 324 A P+E A + + ++P +LP +K DK +ATR+ Sbjct: 330 AEEEANWHKACAEYKAKYPKEWAEFEALTSCKLPENWEAALPHFKPEDKGLATRQHSQTM 389 Query: 325 LAKLGHASDRIIALDGDTKNSTFS------EIFKKEHPDRFIECYIAEQNMVSIAVGCAT 378 + L A +I D S + + K + +R + + E M +I G A Sbjct: 390 INALAPALPGLIGGSADLAPSNLTLMKISGDFQKGSYAERNLRFGVREHAMGAICNGIAL 449 Query: 379 -RNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMF 437 ++ +P+C+TF F + +RM+A+SE+ + +H + +GEDGP+ +E LA F Sbjct: 450 HKSGLIPYCATFYIFTDYMRNAMRMSALSEAGVVYVMTHDSIGLGEDGPTHQPIEHLASF 509 Query: 438 RSVPTSTVFYPSDGVATEKAVELA-ANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVL 496 R++P + P+ G T A ++A AN K I SR I N + + A + Sbjct: 510 RAMPDMLMIRPAGGNETAGAYKVAIANRKRPTTIALSRQNMPNIPNCSVEGVAKGAYTIH 569 Query: 497 KSK---DDQVTVIGAGVTLHEALAAAELLKKEKINIRVL 532 +K V ++G G L A AAA +L+KE N+RV+ Sbjct: 570 DTKAGVKPDVILMGTGSELELATAAAGILEKEGKNVRVV 608 >2R8P-A nrPDB Length = 669 Score = 177 bits (448), Expect = 1e-44, Method: Compositional matrix adjust. Identities = 184/684 (26%), Positives = 280/684 (40%), Gaps = 96/684 (14%) Query: 12 LQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRF 71 + + K+ AN +R S+ A A SGHP + A+I VL+ +++ Q+P DRF Sbjct: 1 MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRF 60 Query: 72 VLSKGHAAPILYAVWAEAGF-LAEAELLNLRKISSDLDGHP-VPKQAFTDVATGSLGQGL 129 VLS GH + ++Y++ G+ L EL N R++ S GHP V A + TG LGQG+ Sbjct: 61 VLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGI 120 Query: 130 GAACGMAYTGKYF---------DKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 A GMA K D + Y +GDG + EG E + A KL L+A Sbjct: 121 ANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMMEGISHEVCSLAGTLKLGKLIA 180 Query: 181 ILDINRLGQSDPAPLQHQM-DIYQKRCEAFGWHAII-VDGHSVEELCKAFGQAK---HQP 235 D N G S ++ D R EA+GWH I +DGH + +A +A+ +P Sbjct: 181 FYDDN--GISIDGHVEGWFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKP 238 Query: 236 TAIIAKTFKGRGITGVEDKESWHGKPLP-------------KNMAEQIIQEIYSQIQSKK 282 + ++ KT G G HG PL K +I EIY+Q +K+ Sbjct: 239 SLLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKE 298 Query: 283 KILATP--------------PQEDAPSVDIANIRMPSLPSYKVGD----------KIATR 318 A PQE A MPS K + KIA+R Sbjct: 299 AGQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASR 358 Query: 319 KAYGQALAKLGHASDRIIALDGDTKNSTF-----SEIFKKEHPDRFIECYIAEQNMVSIA 373 KA A+ G + D S S+ ++ +I + E M +IA Sbjct: 359 KASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINEDAAGNYIHYGVREFGMTAIA 418 Query: 374 VGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALED 433 G + +P+ STF F A + +RMAA+ + + +H + +GEDGP+ +E Sbjct: 419 NGISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQ 478 Query: 434 LAMFRSVPTSTVFYPSDGVATEKAVELAANTK-GICFIRTSRPENAIIYNNNEDF-QVGQ 491 +A R P + + P D V + A + + G + SR A E + + Sbjct: 479 VASLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIAR 538 Query: 492 AKVVLK--SKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSA 549 VLK + ++ I G + A+AA E L E + RV+ + D++ D+A Sbjct: 539 GGYVLKDCAGQPELIFIATGSEVELAVAAYEKLTAEGVKARVVSMPSTDAFDKQ---DAA 595 Query: 550 -------RATKGRILT---VEDHYYE--GGIGEAVSSAVVGEPGITVTHLAVNRVPRSGK 597 +A R+ + D++Y+ G G V GE Sbjct: 596 YRESVLPKAVTARVAVEAGIADYWYKYVGLNGAIVGMTTFGESA---------------- 639 Query: 598 PAELL-KMFGIDRDAIAQAVRGLI 620 PAELL + FG D + + L+ Sbjct: 640 PAELLFEEFGFTVDNVVAKAKELL 663 >4XEU-A nrPDB Length = 673 Score = 175 bits (444), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 158/580 (27%), Positives = 253/580 (43%), Gaps = 66/580 (11%) Query: 16 KDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSK 75 ++ AN +R S+ A A SGHP + A+I VL+ M++ +P+ + DRFVLS Sbjct: 13 RERANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDYMQHNPSNPQWANRDRFVLSN 72 Query: 76 GHAAPILYAVWAEAGF-LAEAELLNLRKISSDLDGHP-VPKQAFTDVATGSLGQGLGAAC 133 GH + ++Y++ G+ L +L N R+++S GHP A + TG LGQG+ A Sbjct: 73 GHGSMLIYSLLHLTGYDLGIEDLKNFRQLNSRTPGHPEYGYTAGVETTTGPLGQGIANAV 132 Query: 134 GMAYTGKY----FDKASYRV-----YCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDI 184 GMA K F++ + V Y LGDG + EG E + A +L+ L+A D Sbjct: 133 GMALAEKVLAAQFNRDGHAVVDHYTYAFLGDGCMMEGISHEVASLAGTLRLNKLIAFYDD 192 Query: 185 NRLGQSDPAPLQHQMDIYQKRCEAFGWHAII-VDGHSVEELCKAFGQAKH--QPTAIIAK 241 N + D D KR EA+GW I VDGH +E+ A A+ QPT I K Sbjct: 193 NGI-SIDGEVHGWFTDDTPKRFEAYGWQVIRNVDGHDADEIKTAIDTARKSDQPTLICCK 251 Query: 242 TFKGRGITGVEDKESWHGKPLP-------------KNMAEQIIQEIYSQIQSKKK----- 283 T G G + KE HG PL ++ +I +IY++ +K+ Sbjct: 252 TVIGFGSPNKQGKEECHGAPLGADEIAATRAALGWEHAPFEIPAQIYAEWDAKETGAAQE 311 Query: 284 ---------ILATPPQEDAPSVDIANIRMPSLPSYKV----------GDKIATRKAYGQA 324 A P+ A + +P+ + K G+ IA+RKA A Sbjct: 312 AEWNKRFAAYQAAHPELAAELLRRLKGELPADFAEKAAAYVADVANKGETIASRKASQNA 371 Query: 325 LAKLGHASDRIIALDGDTKNSTFS------EIFKKEHPDRFIECYIAEQNMVSIAVGCAT 378 L G ++ D S + + + ++ + E M +I G A Sbjct: 372 LNAFGPLLPELLGGSADLAGSNLTLWKGCKGVSADDAAGNYVFYGVREFGMSAIMNGVAL 431 Query: 379 RNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFR 438 +P+ +TF F A + +RM+A+ + + +H + +GEDGP+ +E LA R Sbjct: 432 HGGFIPYGATFLIFMEYARNAVRMSALMKQRVLYVFTHDSIGLGEDGPTHQPIEQLASLR 491 Query: 439 SVPTSTVFYPSD----GVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKV 494 P + P+D VA + A+E A + F R + P A D + + Sbjct: 492 LTPNLDTWRPADAVESAVAWKHAIERADGPSALIFSRQNLPHQARDVAQVAD--IARGGY 549 Query: 495 VLK--SKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL 532 VLK + ++ +I G + A+ A + L ++ +RV+ Sbjct: 550 VLKDCEGEPELILIATGSEVGLAVQAYDKLSEQGRKVRVV 589 >1GPU-A nrPDB Length = 680 Score = 172 bits (437), Expect = 3e-43, Method: Compositional matrix adjust. Identities = 179/668 (26%), Positives = 279/668 (41%), Gaps = 87/668 (13%) Query: 22 LRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPI 81 +RI ++ + A SGHP + A VL+ MR +P + DRFVLS GHA + Sbjct: 15 IRILAVDTVSKANSGHPGAPLGMAPAAHVLW-SQMRMNPTNPDWINRDRFVLSNGHAVAL 73 Query: 82 LYAVWAEAGF-LAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMA---- 136 LY++ G+ L+ +L R++ S GHP + +V TG LGQG+ A GMA Sbjct: 74 LYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVGMAMAQA 133 Query: 137 -----YTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSD 191 Y F + Y LGDG L EG EA + A KL NL+AI D N++ Sbjct: 134 NLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDNKITIDG 193 Query: 192 PAPLQHQMDIYQKRCEAFGWHAIIVDG--HSVEELCKAFGQAK---HQPTAIIAKTFKGR 246 + D+ KR EA+GW + V+ + + KA QAK +PT I T G Sbjct: 194 ATSISFDEDV-AKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKMTTTIGY 252 Query: 247 GITGVEDKESWHGKPLPKNMAEQ--------------IIQEIYSQIQ-----------SK 281 G S HG PL + +Q + QE+Y Q +K Sbjct: 253 GSLHA-GSHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPGVEANNK 311 Query: 282 KKILATPPQEDAPSVDIANIR-----MPS-----LPSYKVGDK-IATRKAYGQALAKLGH 330 L + Q+ P + R +P+ LP+Y D +ATRK L + + Sbjct: 312 WNKLFSEYQKKFPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETVLEDVYN 371 Query: 331 ASDRIIALDGDTKNSTFS---EIFKKEHPD--------RFIECYIAEQNMVSIAVGCATR 379 +I D S + E + P R+I I E M +I G + Sbjct: 372 QLPELIGGSADLTPSNLTRWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIMNGISAF 431 Query: 380 NRTV-PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFR 438 P+ TF F + A +R++A+S + +H + +GEDGP+ +E LA FR Sbjct: 432 GANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQPIETLAHFR 491 Query: 439 SVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKS 498 S+P V+ P+DG A + + +K I +N + + VL+ Sbjct: 492 SLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKGGYVLQD 551 Query: 499 -KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL---DPFTI--KPLDRKLILDSARAT 552 + + ++ G + ++ AA+ L + I RV+ D FT +PL+ +L S Sbjct: 552 VANPDIILVATGSEVSLSVEAAKTLAAKNIKARVVSLPDFFTFDKQPLEYRL---SVLPD 608 Query: 553 KGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDRDAI 612 I++V E +++ G+ ++R SGK E+ K FG + + Sbjct: 609 NVPIMSV----------EVLATTCWGK--YAHQSFGIDRFGASGKAPEVFKFFGFTPEGV 656 Query: 613 AQAVRGLI 620 A+ + I Sbjct: 657 AERAQKTI 664 >1ITZ-A nrPDB Length = 675 Score = 163 bits (413), Expect = 2e-40, Method: Compositional matrix adjust. Identities = 181/684 (26%), Positives = 286/684 (41%), Gaps = 103/684 (15%) Query: 13 QALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFV 72 + L+ + N +R +I A A SGHP A + VL+ MRY ++P + DRFV Sbjct: 14 ELLEKSVNTIRFLAIDAVEKANSGHPGLPMGCAPMGHVLYDEVMRYNPKNPYWFNRDRFV 73 Query: 73 LSKGHAAPILYAVWAEAGF--LAEAELLNLRKISSDLDGHPVP-KQAFTDVATGSLGQGL 129 LS GH + YA+ AG+ + E +L R+ S GHP + +V TG LGQG+ Sbjct: 74 LSAGHGCMLQYALLHLAGYDSVKEEDLKQFRQWGSRTPGHPENFETPGVEVTTGPLGQGI 133 Query: 130 GAACGMAYTGKY----FDK-----ASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 A G+A K+ F+K + Y +LGDG EG EA + A + L L+A Sbjct: 134 ANAVGLALAEKHLAARFNKPDSEIVDHYTYVILGDGCQMEGIANEACSLAGHWGLGKLIA 193 Query: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIV-DGHS-VEELCKAFGQAK---HQP 235 D N + + D+ R EA GWH I V +G++ +++ A +AK +P Sbjct: 194 FYDDNHISIDGDTEIAFTEDV-STRFEALGWHTIWVKNGNTGYDDIRAAIKEAKAVTDKP 252 Query: 236 TAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEI---YSQIQSKKKILA-----T 287 T I T G G + S HG L E Q + Y + + + T Sbjct: 253 TLIKVTTTIGFGSPNKANSYSVHGSALGAKEVEATRQNLGWPYDTFFVPEDVKSHWSRHT 312 Query: 288 PP-------------------QEDAPSV-DIANIRMPS-----LPSY---KVGDKIATRK 319 P +DA ++ I +P+ LP Y GD ATR Sbjct: 313 PEGAALEADWNAKFAEYEKKYADDAATLKSIITGELPTGWVDALPKYTPESPGD--ATRN 370 Query: 320 AYGQALAKLGHASDRIIALDGDTKNST------FSEIFKKEHPDRFIECYIAEQNMVSIA 373 Q L L + +I D +S F + K +R + + E M +I Sbjct: 371 LSQQCLNALANVVPGLIGGSADLASSNMTLLKMFGDFQKDTAEERNVRFGVREHGMGAIC 430 Query: 374 VGCATRNRT-VPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALE 432 G A + VP+C+TF F +R++A+SE+ + +H + +GEDGP+ +E Sbjct: 431 NGIALHSPGFVPYCATFFVFTDYMRGAMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIE 490 Query: 433 DLAMFRSVPTSTVFYPSDGVATEKAVELAA-NTKGICFIRTSR------PENAIIYNNNE 485 L FR++P + P+DG T A ++A N K + SR P +I E Sbjct: 491 HLVSFRAMPNILMLRPADGNETAGAYKVAVLNRKRPSILALSRQKLPHLPGTSI-----E 545 Query: 486 DFQVGQAKVVLKSKDDQ--VTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRK 543 + G + S ++ + V+G G L A AA+ L+KE +RV+ + + D + Sbjct: 546 GVEKGGYTISDNSTGNKPDLIVMGTGSELEIAAKAADELRKEGKTVRVVSFVSWELFDEQ 605 Query: 544 LILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTH----------LAVNRVP 593 D Y E + AV++ + E G T+ + +++ Sbjct: 606 ----------------SDEYKESVLPAAVTARISIEAGSTLGWQKYVGAQGKAIGIDKFG 649 Query: 594 RSGKPAELLKMFGIDRDAIAQAVR 617 S + K +GI ++I A + Sbjct: 650 ASAPAGTIYKEYGITVESIIAAAK 673 >3RIM-A nrPDB Length = 700 Score = 141 bits (355), Expect = 1e-33, Method: Compositional matrix adjust. Identities = 162/650 (24%), Positives = 256/650 (39%), Gaps = 95/650 (14%) Query: 20 NRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAA 79 + +R+ + A G+GHP + S A + LF TMR+ D DRFVLS GH++ Sbjct: 28 DTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFVLSAGHSS 87 Query: 80 PILYAVWAEAGF-LAEAELLNLRKISSDLDGHPVPKQA-FTDVATGSLGQGLGAACGMAY 137 LY GF L +++ +LR S GHP + ++ TG LGQGL +A GMA Sbjct: 88 LTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMAM 147 Query: 138 TGKY----FDKAS--------YRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185 +Y FD + + +Y + DG++ EG EA + A++ +L NL+ D N Sbjct: 148 ASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDRN 207 Query: 186 RLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGH----SVEELCKAFGQAKHQPTAIIAK 241 ++ D + D R A+GWH V+G +EE +P+ I + Sbjct: 208 QISIEDDTNIALCEDT-AARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIALR 266 Query: 242 TFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIY----SQIQSKKKILA----------- 286 T G + D HG L + + + + Q ++ +L Sbjct: 267 TVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGLVARGKQ 326 Query: 287 --------------TPPQEDAPSVDIANIRMP-----SLPSYKVGDK-IATRKAYGQALA 326 P+ A + ++P LP ++ G K +ATR A G L+ Sbjct: 327 AHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVLS 386 Query: 327 KLGHASDRIIALDGD---TKNSTFS--------EIFKKEHP----DRFIECYIAEQNMVS 371 LG + D + N+T I KE+ R + + E M + Sbjct: 387 ALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMGA 446 Query: 372 IAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMAL 431 I G T + TF F +R+AA+ + + +H + +GEDGP+ + Sbjct: 447 ILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQPI 506 Query: 432 EDLAMFRSVPTSTVFYPSDGVATEKAVEL------AANTKGICFIRTSRPENAIIYNNNE 485 E L+ R++P +V P+D T A + G+ R P + + + Sbjct: 507 EHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVP----VLDGTD 562 Query: 486 DFQVGQAKVVLK-------SKDDQVTVIGAGVTLHEALAAAELLKKEKINIRV-----LD 533 V + VL ++ V +I G + A+AA LL I RV L+ Sbjct: 563 AEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCLE 622 Query: 534 PFTIKPLD-RKLILD---SARATKGRILTVEDHYYEGGIGEAVSSAVVGE 579 F +P + R +L SAR + H G GE VS GE Sbjct: 623 WFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGE 672 >2O1X-A nrPDB Length = 629 Score = 99.8 bits (247), Expect = 4e-21, Method: Compositional matrix adjust. Identities = 97/369 (26%), Positives = 153/369 (41%), Gaps = 59/369 (15%) Query: 216 VDGHSVEELCKAFGQAKH--QPTAIIAKTFKGRGITGVE-DKESWHGKPLPKNMAEQIIQ 272 VDGH+V+EL + PT + T KG+G++ E D WHG Sbjct: 259 VDGHNVQELVWLLERLVDLDGPTILHIVTTKGKGLSYAEADPIYWHG------------- 305 Query: 273 EIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHAS 332 P + D P+ Y + A+G+A+ + Sbjct: 306 ---------------PAKFD-----------PATGEYVPSSAYSWSAAFGEAVTEWAKTD 339 Query: 333 DRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAF 392 R + + + F + HP R+++ IAE+ V+ A G A + P + ++ F Sbjct: 340 PRTFVVTPAMREGSGLVEFSRVHPHRYLDVGIAEEVAVTTAAGMALQGMR-PVVAIYSTF 398 Query: 393 FTRAFDQI-RMAAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDG 451 RA+DQ+ AI N+ C G+ +G DG + + DL+ RS+P + P D Sbjct: 399 LQRAYDQVLHDVAIEHLNVTFCIDRAGI-VGADGATHNGVFDLSFLRSIPGVRIGLPKDA 457 Query: 452 VATEKAVELAANTKGICFIRTSRPENA-IIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGV 510 ++ A G IR R A + D + G+ + LK DD V ++ G Sbjct: 458 AELRGMLKYAQTHDGPFAIRYPRGNTAQVPAGTWPDLKWGEWE-RLKGGDD-VVILAGGK 515 Query: 511 TLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGR---ILTVEDHYYEGG 567 L AL AAE L + V++ +KPLD +++ R GR ++TVED+ GG Sbjct: 516 ALDYALKAAEDLP----GVGVVNARFVKPLDEEML----REVGGRARALITVEDNTVVGG 567 Query: 568 IGEAVSSAV 576 G AV A+ Sbjct: 568 FGGAVLEAL 576 >2O1S-A nrPDB Length = 621 Score = 96.3 bits (238), Expect = 4e-20, Method: Compositional matrix adjust. Identities = 117/497 (23%), Positives = 206/497 (41%), Gaps = 56/497 (11%) Query: 110 HPVPKQAFTDVATGSLGQ-------GLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGS 162 HP P + ++ S+G G+G A GK + R C++GDG ++ G Sbjct: 105 HPFPWRGESEYDVLSVGHSSTSISAGIGIAVAAEKEGK-----NRRTVCVIGDGAITAGM 159 Query: 163 VWEAMAFASIYKLDNLVAILDINRLGQSDP-APLQHQM------DIYQKRCEAFGWHAII 215 +EAM A + D LV IL+ N + S+ L + + +Y E G + Sbjct: 160 AFEAMNHAGDIRPDMLV-ILNDNEMSISENVGALNNHLAQLLSGKLYSSLRE--GGKKVF 216 Query: 216 VDGHSVEELCKAFGQAKHQPTAIIAKTF---KGRGITGVEDKESWHGKPLPKNMAEQIIQ 272 ++EL K +H ++ T G G D G + Sbjct: 217 SGVPPIKELLKR--TEEHIKGMVVPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKG 274 Query: 273 EIYSQIQSKKKILATPPQED------APSVDIANIRMP----SLPSYKVGDKIATRKAYG 322 + I +KK P ++D P D ++ +P LPSY K +G Sbjct: 275 PQFLHIMTKKGRGYEPAEKDPITFHAVPKFDPSSGCLPKSSGGLPSYS--------KIFG 326 Query: 323 QALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRT 382 L + ++++A+ + + F ++ PDR+ + IAEQ+ V+ A G A Sbjct: 327 DWLCETAAKDNKLMAITPAMREGSGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYK 386 Query: 383 VPFCSTFAAFFTRAFDQIRM-AAISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVP 441 P + ++ F RA+DQ+ AI + + G+ +G DG + DL+ R +P Sbjct: 387 -PIVAIYSTFLQRAYDQVLHDVAIQKLPVLFAIDRAGI-VGADGQTHQGAFDLSYLRCIP 444 Query: 442 TSTVFYPSDGVATEKAVELAAN-TKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKD 500 + PSD + + + G +R R NA+ ++ K ++K + Sbjct: 445 EMVIMTPSDENECRQMLYTGYHYNDGPSAVRYPR-GNAVGVELTPLEKLPIGKGIVKRRG 503 Query: 501 DQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVE 560 +++ ++ G + EA AE L +++R +KPLD LIL+ A A+ ++TVE Sbjct: 504 EKLAILNFGTLMPEAAKVAESLNATLVDMRF-----VKPLDEALILEMA-ASHEALVTVE 557 Query: 561 DHYYEGGIGEAVSSAVV 577 ++ GG G V+ ++ Sbjct: 558 ENAIMGGAGSGVNEVLM 574 >3LQ2-A nrPDB Length = 886 Score = 58.5 bits (140), Expect = 8e-09, Method: Compositional matrix adjust. Identities = 59/203 (29%), Positives = 88/203 (43%), Gaps = 16/203 (7%) Query: 36 GHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEA 95 GH S S+A I V F H R +++ V +GH +P +YA G L + Sbjct: 105 GHMASFQSSATIYDVCFNHFFRARNEQ----DGGDLVYFQGHISPGVYARAFLEGRLTQE 160 Query: 96 ELLNLRK--ISSDLDGHPVPK--QAFTDVATGSLGQGLGAACGMAYTGKYF------DKA 145 +L N R+ + L +P PK F T S+G G A A KY D + Sbjct: 161 QLDNFRQEVHGNGLSSYPHPKLMPEFWQFPTVSMGLGPIGAIYQAKFLKYLEHRGLKDTS 220 Query: 146 SYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQ-MDIYQK 204 VY LGDGE+ A+ A+ KLDNLV +++ N P + ++ + Sbjct: 221 KQTVYAFLGDGEMDAPESKGAITIATREKLDNLVFVINCNLQRLDGPVTGNGKIINELEG 280 Query: 205 RCEAFGWHAI-IVDGHSVEELCK 226 E GW+ I ++ G +EL + Sbjct: 281 IFEGAGWNVIKVMWGSRWDELLR 303 >1IK6-A nrPDB Length = 369 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 78/308 (25%), Positives = 125/308 (40%), Gaps = 49/308 (15%) Query: 319 KAYGQALAKLGHASDRIIALDGDT--KNSTF---SEIFKKEHPDRFIECYIAEQNMVSIA 373 KA AL + +R++ L D K F ++++ P+R I+ + E ++ A Sbjct: 55 KAINMALHEEMERDERVVVLGEDVGKKGGVFLVTEGLYERFGPERVIDTPLNEGGILGFA 114 Query: 374 VGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSH-------CGVSIGEDGP 426 +G A F F D++ + I++ G++ V G G Sbjct: 115 MGMAMAGLKPVAEIQFVDFIWLGADEL-LNHIAKLRYRSGGNYKAPLVVRTPVGSGTRGG 173 Query: 427 SQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGI--CFIRTSRP----ENAII 480 + A+F P V PS N KG+ IR P E I+ Sbjct: 174 LYHSNSPEAIFVHTPGLVVVMPST----------PYNAKGLLKAAIRGDDPVVFLEPKIL 223 Query: 481 YNNNED--------FQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVL 532 Y + ++G+A+V + D VT++ G +H+AL AAE + K ++ V+ Sbjct: 224 YRAPREEVPEGDYVVEIGKARVA--REGDDVTLVTYGAVVHKALEAAE---RVKASVEVV 278 Query: 533 DPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGI-----TVTHL 587 D T+ PLD +L S T GR++ D GG+G V A+V E + V L Sbjct: 279 DLQTLNPLDFDTVLKSVSKT-GRLIIAHDSPKTGGLGAEV-RALVAEKALDRLTAPVIRL 336 Query: 588 AVNRVPRS 595 A VP+S Sbjct: 337 AGPDVPQS 344 >3DV0-B nrPDB Length = 325 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 31/88 (35%), Positives = 52/88 (59%), Gaps = 3/88 (3%) Query: 489 VGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDS 548 +G+A + + KD +T+I G +HE+L AA L+KE I+ V+D T++PLD + I+ S Sbjct: 193 IGKADIKREGKD--ITIIAYGAMVHESLKAAAELEKEGISAEVVDLRTVQPLDIETIIGS 250 Query: 549 ARATKGRILTVEDHYYEGGIGEAVSSAV 576 T GR + V++ + GI V + + Sbjct: 251 VEKT-GRAIVVQEAQRQAGIAANVVAEI 277 >6CFO-B nrPDB Length = 341 Score = 49.7 bits (117), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 72/321 (22%), Positives = 125/321 (38%), Gaps = 43/321 (13%) Query: 314 KIATRKAYGQALAKLGHASDRIIAL-------DGDTKNSTFSEIFKKEHPDRFIECYIAE 366 ++ R A Q + + +++ L DG K S ++KK R I+ I+E Sbjct: 14 QVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVS--RGLWKKYGDKRIIDTPISE 71 Query: 367 QNMVSIAVGCATRNRTVPFCSTFAAFFT-RAFDQIRMAAISESNINLCGSHCGVSIGEDG 425 IAVG A P C F+ +A DQ+ +A + G V I G Sbjct: 72 MGFAGIAVGAAMAGLR-PICEFMTFNFSMQAIDQVINSA--AKTYYMSGGLQPVPIVFRG 128 Query: 426 P--------SQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRP-- 475 P +Q + A + P V P + + ++ A IR + P Sbjct: 129 PNGASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSA--------IRDNNPVV 180 Query: 476 --ENAIIYN---------NNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKK 524 EN ++Y ++DF + K ++ + +TV+ + L AA +L K Sbjct: 181 VLENELMYGVPFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSK 240 Query: 525 EKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITV 584 E + V++ TI+P+D + I S T ++TVE + + G+G + + ++ P Sbjct: 241 EGVECEVINMRTIRPMDMETIEASVMKTN-HLVTVEGGWPQFGVGAEICARIMEGPAFNF 299 Query: 585 THLAVNRVPRSGKPAELLKMF 605 RV + P K+ Sbjct: 300 LDAPAVRVTGADVPMPYAKIL 320 >1UMC-B nrPDB Length = 324 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 54/224 (24%), Positives = 94/224 (41%), Gaps = 17/224 (7%) Query: 350 IFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESN 409 + +K PDR ++ ++E +V A+G A FA + FDQ+ ++ +++ Sbjct: 44 LLQKYGPDRVMDTPLSEAAIVGAALGMAAHGLRPVAEIQFADYIFPGFDQL-VSQVAKLR 102 Query: 410 INLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGI-- 467 G + PS + P + F + G+ AV + KG+ Sbjct: 103 YR-SGGQFTAPLVVRMPSGGGVRGGHHHSQSPEAH-FVHTAGLKV-VAVSTPYDAKGLLK 159 Query: 468 CFIRTSRP----ENAIIYNN------NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALA 517 IR P E +Y + ED+ + K L+ + +T+I G + E L Sbjct: 160 AAIRDEDPVVFLEPKRLYRSVKEEVPEEDYTLPIGKAALRREGKDLTLICYGTVMPEVLQ 219 Query: 518 AAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVED 561 AA L K ++ VLD T+ P D + +++S A GR++ V D Sbjct: 220 AAAELAKAGVSAEVLDLRTLMPWDYEAVMNSV-AKTGRVVLVSD 262 >3DVA-A nrPDB Length = 369 Score = 35.4 bits (80), Expect = 0.065, Method: Compositional matrix adjust. Identities = 29/92 (31%), Positives = 39/92 (42%), Gaps = 6/92 (6%) Query: 127 QGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINR 186 Q G A G+ GK KA Y GDG S+G +E + FA +K + + + NR Sbjct: 151 QAAGVALGLKMRGK---KAVAITYT--GDGGTSQGDFYEGINFAGAFKAPAIFVVQN-NR 204 Query: 187 LGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDG 218 S P Q ++ A G I VDG Sbjct: 205 FAASTPVEKQTVAKTLAQKAVAAGIPGIQVDG 236 >3EXI-A nrPDB Length = 382 Score = 33.5 bits (75), Expect = 0.27, Method: Compositional matrix adjust. Identities = 23/64 (35%), Positives = 35/64 (54%), Gaps = 8/64 (12%) Query: 125 LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDI 184 LG G+ AC Y GK D+ +Y GDG ++G ++EA A+++KL + I + Sbjct: 165 LGAGIALAC--KYNGK--DEVCLTLY---GDGAANQGQIFEAYNMAALWKLP-CIFICEN 216 Query: 185 NRLG 188 NR G Sbjct: 217 NRYG 220 >6GUA-A nrPDB Length = 822 Score = 33.1 bits (74), Expect = 0.34, Method: Compositional matrix adjust. Identities = 27/109 (24%), Positives = 47/109 (43%), Gaps = 7/109 (6%) Query: 123 GSLGQG--LGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSV---WEAMAFASIYKLDN 177 GSL +G LG A TG D+ + ++GDGE G + W ++ F + Sbjct: 140 GSLHEGGELGYVLSHA-TGAILDQPEQIAFAVVGDGEAETGPLMTSWHSIKFINPKNDGA 198 Query: 178 LVAILDINRLGQSDPAPLQHQMDI-YQKRCEAFGWHAIIVDGHSVEELC 225 ++ ILD+N S+P D+ +K E G+ ++ + + Sbjct: 199 ILPILDLNGFKISNPTLFARTSDVDIRKFFEGLGYSPRYIENDDIHDYM 247 >5WWT-A nrPDB Length = 477 Score = 33.1 bits (74), Expect = 0.34, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 43/99 (43%), Gaps = 1/99 (1%) Query: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300 K F G GI+ + KE + G P K M ++ + +Y + ++ PS +++ Sbjct: 169 KVFLGNGISELSRKEIFSGLPELKGMGIRMTEPVYLSPSFDSVLPRYLFLQNLPSALVSH 228 Query: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALD 339 + P P K+ D A +A L H +IALD Sbjct: 229 VLNPQ-PGEKILDLCAAPGGKTTHIAALMHDQGEVIALD 266 >1X7Z-A nrPDB Length = 400 Score = 33.1 bits (74), Expect = 0.38, Method: Compositional matrix adjust. Identities = 28/102 (27%), Positives = 44/102 (43%), Gaps = 7/102 (6%) Query: 149 VYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEA 208 V C G+G SEG FA+ + ++ N S P Q++ D R Sbjct: 187 VICYFGEGAASEGDAHAGFNFAATLECP-IIFFCRNNGYAISTPTSEQYRGDGIAARGPG 245 Query: 209 FGWHAIIVDGHSVEELCKAFGQAK------HQPTAIIAKTFK 244 +G +I VDG+ V + A +A+ +QP I A T++ Sbjct: 246 YGIMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMTYR 287 >2J3M-A nrPDB Length = 572 Score = 32.7 bits (73), Expect = 0.42, Method: Compositional matrix adjust. Identities = 24/89 (26%), Positives = 42/89 (47%), Gaps = 4/89 (4%) Query: 269 QIIQEIYSQIQSKKKILA---TPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQAL 325 Q+ IYS + ++L T +E+ +D + MP+L ++ + + YG L Sbjct: 34 QVAAGIYSYLPLANRVLEKLKTIMREEFEKIDAVEMLMPALLPAELWKESGRYETYGPNL 93 Query: 326 AKLGHASDRIIALDGDTKNSTFSEIFKKE 354 +L +DR L G T TF+E+ + E Sbjct: 94 YRLKDRNDRDYIL-GPTHEETFTELIRDE 121 >1O5W-A nrPDB Length = 534 Score = 29.6 bits (65), Expect = 3.8, Method: Compositional matrix adjust. Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 3/31 (9%) Query: 503 VTVIGAGVTLHEALAAAELLKKEKINIRVLD 533 V VIG G++ LAAA+LL + KIN+ VL+ Sbjct: 24 VVVIGGGIS---GLAAAKLLSEYKINVLVLE 51 >3AHE-A nrPDB Length = 845 Score = 28.9 bits (63), Expect = 6.5, Method: Compositional matrix adjust. Identities = 24/84 (28%), Positives = 38/84 (45%), Gaps = 6/84 (7%) Query: 117 FTDVATGSLGQG--LGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSV---WEAMAFAS 171 F GS+ +G LG A AY G + S V C++GDGE G + W++ + Sbjct: 163 FAPETPGSIHEGGELGYALSHAY-GAVMNNPSLFVPCIIGDGEAETGPLATGWQSNKLVN 221 Query: 172 IYKLDNLVAILDINRLGQSDPAPL 195 ++ IL +N ++P L Sbjct: 222 PRTDGIVLPILHLNGYKIANPTIL 245 >6O7W-C nrPDB Length = 639 Score = 28.5 bits (62), Expect = 9.0, Method: Compositional matrix adjust. Identities = 23/86 (26%), Positives = 37/86 (43%), Gaps = 9/86 (10%) Query: 259 GKPLPKNMAEQIIQEIYSQIQSKKKILATPPQE-------DAPSVDIANIRMPSLPS-YK 310 GKPL + +++ IY IQ K + Q D P++D I+ P ++ Sbjct: 90 GKPLSVELGPGLMETIYDGIQRPLKAIKEESQSIYIPRGIDTPALD-RTIKWQFTPGKFQ 148 Query: 311 VGDKIATRKAYGQALAKLGHASDRII 336 VGD I+ YG +S +I+ Sbjct: 149 VGDHISGGDIYGSVFENSLISSHKIL 174 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4KXX-A nrPDB 811 0.0 2R8P-A nrPDB 666 0.0 5ND5-A nrPDB 657 0.0 1ITZ-A nrPDB 652 0.0 4XEU-A nrPDB 648 0.0 1GPU-A nrPDB 638 0.0 3RIM-A nrPDB 553 e-158 2O1S-A nrPDB 424 e-119 2O1X-A nrPDB 310 1e-84 6CFO-B nrPDB 255 6e-68 3LQ2-A nrPDB 225 4e-59 1IK6-A nrPDB 215 4e-56 1UMC-B nrPDB 206 2e-53 3DV0-B nrPDB 164 9e-41 Sequences not found previously or not previously below threshold: 1QS0-B nrPDB 145 5e-35 1X7Z-A nrPDB 53 5e-07 5B46-A nrPDB 43 3e-04 3EXI-A nrPDB 43 4e-04 1UM9-A nrPDB 43 5e-04 3DVA-A nrPDB 40 0.003 3UIM-A nrPDB 36 0.057 3OIC-A nrPDB 35 0.083 4Q9D-A nrPDB 33 0.47 6GUA-A nrPDB 33 0.49 1PYP-A nrPDB 31 1.2 1J3Q-A nrPDB 31 1.5 3O0O-A nrPDB 31 1.9 2QNE-A nrPDB 31 2.3 4ZP1-A nrPDB 31 2.3 4MX8-A nrPDB 29 5.4 4RNL-A nrPDB 29 7.6 >4KXX-A nrPDB Length = 637 Score = 811 bits (2095), Expect = 0.0, Method: Composition-based stats. Identities = 623/623 (100%), Positives = 623/623 (100%) Query: 1 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS 60 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS Sbjct: 1 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKS 60 Query: 61 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV 120 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV Sbjct: 61 QDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDV 120 Query: 121 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA Sbjct: 121 ATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 Query: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA 240 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA Sbjct: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIA 240 Query: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN Sbjct: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIAN 300 Query: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI 360 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI Sbjct: 301 IRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNSTFSEIFKKEHPDRFI 360 Query: 361 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS 420 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS Sbjct: 361 ECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVS 420 Query: 421 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII Sbjct: 421 IGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAII 480 Query: 481 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL 540 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL Sbjct: 481 YNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPL 540 Query: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE Sbjct: 541 DRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAE 600 Query: 601 LLKMFGIDRDAIAQAVRGLITKA 623 LLKMFGIDRDAIAQAVRGLITKA Sbjct: 601 LLKMFGIDRDAIAQAVRGLITKA 623 >2R8P-A nrPDB Length = 669 Score = 666 bits (1717), Expect = 0.0, Method: Composition-based stats. Identities = 175/679 (25%), Positives = 265/679 (39%), Gaps = 86/679 (12%) Query: 12 LQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRF 71 + + K+ AN +R S+ A A SGHP + A+I VL+ +++ Q+P DRF Sbjct: 1 MSSRKELANAIRALSMDAVQKAKSGHPGAPMGMADIAEVLWRDFLKHNPQNPSWADRDRF 60 Query: 72 VLSKGHAAPILYAVWAEAGF-LAEAELLNLRKISSDLDGHPV-PKQAFTDVATGSLGQGL 129 VLS GH + ++Y++ G+ L EL N R++ S GHP A + TG LGQG+ Sbjct: 61 VLSNGHGSMLIYSLLHLTGYDLPMEELKNFRQLHSKTPGHPEVGYTAGVETTTGPLGQGI 120 Query: 130 GAACGMAYTGKYF---------DKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 A GMA K D + Y +GDG + EG E + A KL L+A Sbjct: 121 ANAVGMAIAEKTLAAQFNRPGHDIVDHYTYAFMGDGCMMEGISHEVCSLAGTLKLGKLIA 180 Query: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAII-VDGHSVEELCKAFGQAK---HQPT 236 D N + D R EA+GWH I +DGH + +A +A+ +P+ Sbjct: 181 FYDDNGISIDGHVEG-WFTDDTAMRFEAYGWHVIRDIDGHDAASIKRAVEEARAVTDKPS 239 Query: 237 AIIAKTFKGRGITGVEDKESWHGKPLPK-------------NMAEQIIQEIYSQIQSKKK 283 ++ KT G G HG PL +I EIY+Q +K+ Sbjct: 240 LLMCKTIIGFGSPNKAGTHDSHGAPLGDAEIALTREQLGWKYAPFEIPSEIYAQWDAKEA 299 Query: 284 ILATP--------------PQEDAPSVDIANIRMPSLPSYKVGD----------KIATRK 319 A PQE A MPS K + KIA+RK Sbjct: 300 GQAKESAWNEKFAAYAKAYPQEAAEFTRRMKGEMPSDFDAKAKEFIAKLQANPAKIASRK 359 Query: 320 AYGQALAKLGHASDRIIALDGDTKNSTFS-----EIFKKEHPDRFIECYIAEQNMVSIAV 374 A A+ G + D S + + ++ +I + E M +IA Sbjct: 360 ASQNAIEAFGPLLPEFLGGSADLAPSNLTLWSGSKAINEDAAGNYIHYGVREFGMTAIAN 419 Query: 375 GCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDL 434 G + +P+ STF F A + +RMAA+ + + +H + +GEDGP+ +E + Sbjct: 420 GISLHGGFLPYTSTFLMFVEYARNAVRMAALMKQRQVMVYTHDSIGLGEDGPTHQPVEQV 479 Query: 435 AMFRSVPTSTVFYPSDGVATEKAVELAANT-KGICFIRTSRPENAIIYNNNEDF-QVGQA 492 A R P + + P D V + A + G + SR A E + + Sbjct: 480 ASLRVTPNMSTWRPCDQVESAVAWKYGVERQDGPTALILSRQNLAQQERTEEQLANIARG 539 Query: 493 KVVLKS--KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLD------RKL 544 VLK ++ I G + A+AA E L E + RV+ + D R+ Sbjct: 540 GYVLKDCAGQPELIFIATGSEVELAVAAYEKLTAEGVKARVVSMPSTDAFDKQDAAYRES 599 Query: 545 ILD---SARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAEL 601 +L +AR + + Y G G V GE S L Sbjct: 600 VLPKAVTARVAVEAGIADYWYKYVGLNGAIVGMTTFGE---------------SAPAELL 644 Query: 602 LKMFGIDRDAIAQAVRGLI 620 + FG D + + L+ Sbjct: 645 FEEFGFTVDNVVAKAKELL 663 >5ND5-A nrPDB Length = 692 Score = 657 bits (1694), Expect = 0.0, Method: Composition-based stats. Identities = 172/679 (25%), Positives = 279/679 (41%), Gaps = 90/679 (13%) Query: 15 LKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLS 74 ++ N +R +I A + SGHP A + VL+ M+Y ++P + DRFVLS Sbjct: 29 VEKCINAIRFLAIDAINKSKSGHPGMPMGCAPMGYVLWNEVMKYNPKNPDFFNRDRFVLS 88 Query: 75 KGHAAPILYAVWAEAGF--LAEAELLNLRKISSDLDGHPV-PKQAFTDVATGSLGQGLGA 131 GH + Y++ G+ + ++ R+ +S GHP +V TG LGQG+ Sbjct: 89 AGHGSMFQYSMMHLTGYDSVPLDQIKQFRQWNSLTPGHPENFVTPGVEVTTGPLGQGICN 148 Query: 132 ACGMAYTGKYF----------DKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAI 181 A G+A + + YC+LGDG + EG EA + A + L L+A+ Sbjct: 149 AVGLAVAEAHLAARFNKPDVKPIVDHYTYCILGDGCMMEGISNEACSLAGHWGLGKLIAL 208 Query: 182 LDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIV--DGHSVEELCKAFGQA---KHQPT 236 D N++ + D+ KR EA GWH I V V+ L A QA K +PT Sbjct: 209 YDDNKISIDGHTDISFTEDV-AKRYEALGWHVIHVINGNTDVDGLRAAIAQAKAVKDKPT 267 Query: 237 AIIAKTFKGRGITGVEDKESWHGKPLPKNMA-------------EQIIQEIYSQIQSKKK 283 I T G G D HG PL + ++ Q++Y + K Sbjct: 268 LIKVSTLIGYGSPNKADSHDVHGAPLGPDETAATRKNLNWPYGEFEVPQDVYDVFRGAIK 327 Query: 284 ---------------ILATPPQEDAPSVDIANIRMP-----SLPSYKVGDK-IATRKAYG 322 A P+E A + + ++P +LP +K DK +ATR+ Sbjct: 328 RGAEEEANWHKACAEYKAKYPKEWAEFEALTSCKLPENWEAALPHFKPEDKGLATRQHSQ 387 Query: 323 QALAKLGHASDRIIALDGDTKNSTFS------EIFKKEHPDRFIECYIAEQNMVSIAVGC 376 + L A +I D S + + K + +R + + E M +I G Sbjct: 388 TMINALAPALPGLIGGSADLAPSNLTLMKISGDFQKGSYAERNLRFGVREHAMGAICNGI 447 Query: 377 ATR-NRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDLA 435 A + +P+C+TF F + +RM+A+SE+ + +H + +GEDGP+ +E LA Sbjct: 448 ALHKSGLIPYCATFYIFTDYMRNAMRMSALSEAGVVYVMTHDSIGLGEDGPTHQPIEHLA 507 Query: 436 MFRSVPTSTVFYPSDGVATEKAVELA-ANTKGICFIRTSRPENAIIYNNNEDFQVGQAKV 494 FR++P + P+ G T A ++A AN K I SR I N + + A Sbjct: 508 SFRAMPDMLMIRPAGGNETAGAYKVAIANRKRPTTIALSRQNMPNIPNCSVEGVAKGAYT 567 Query: 495 VLKSK---DDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARA 551 + +K V ++G G L A AAA +L+KE N+RV+ + + + Sbjct: 568 IHDTKAGVKPDVILMGTGSELELATAAAGILEKEGKNVRVVSFPCWELFEEQ-------- 619 Query: 552 TKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHL----------AVNRVPRSGKPAEL 601 Y E + V++ V E + ++ S L Sbjct: 620 --------SAEYKESVLPSDVTARVSVEAATSFGWAKYIGLKGKHVGIDTFGASAPAPTL 671 Query: 602 LKMFGIDRDAIAQAVRGLI 620 + FGI + + +A + + Sbjct: 672 YEKFGITVNHVVEAAKATL 690 >1ITZ-A nrPDB Length = 675 Score = 652 bits (1682), Expect = 0.0, Method: Composition-based stats. Identities = 171/677 (25%), Positives = 272/677 (40%), Gaps = 89/677 (13%) Query: 13 QALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFV 72 + L+ + N +R +I A A SGHP A + VL+ MRY ++P + DRFV Sbjct: 14 ELLEKSVNTIRFLAIDAVEKANSGHPGLPMGCAPMGHVLYDEVMRYNPKNPYWFNRDRFV 73 Query: 73 LSKGHAAPILYAVWAEAGF--LAEAELLNLRKISSDLDGHPV-PKQAFTDVATGSLGQGL 129 LS GH + YA+ AG+ + E +L R+ S GHP + +V TG LGQG+ Sbjct: 74 LSAGHGCMLQYALLHLAGYDSVKEEDLKQFRQWGSRTPGHPENFETPGVEVTTGPLGQGI 133 Query: 130 GAACGMAYTGKYF---------DKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 A G+A K+ + + Y +LGDG EG EA + A + L L+A Sbjct: 134 ANAVGLALAEKHLAARFNKPDSEIVDHYTYVILGDGCQMEGIANEACSLAGHWGLGKLIA 193 Query: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHS--VEELCKAFGQAK---HQP 235 D N + + D+ R EA GWH I V + +++ A +AK +P Sbjct: 194 FYDDNHISIDGDTEIAFTEDV-STRFEALGWHTIWVKNGNTGYDDIRAAIKEAKAVTDKP 252 Query: 236 TAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEI---YSQIQSKKKILA------ 286 T I T G G + S HG L E Q + Y + + + Sbjct: 253 TLIKVTTTIGFGSPNKANSYSVHGSALGAKEVEATRQNLGWPYDTFFVPEDVKSHWSRHT 312 Query: 287 -------------------TPPQEDAPSVDIANIRMP-----SLPSYKVGDK-IATRKAY 321 + A I +P +LP Y ATR Sbjct: 313 PEGAALEADWNAKFAEYEKKYADDAATLKSIITGELPTGWVDALPKYTPESPGDATRNLS 372 Query: 322 GQALAKLGHASDRIIALDGDTKNST------FSEIFKKEHPDRFIECYIAEQNMVSIAVG 375 Q L L + +I D +S F + K +R + + E M +I G Sbjct: 373 QQCLNALANVVPGLIGGSADLASSNMTLLKMFGDFQKDTAEERNVRFGVREHGMGAICNG 432 Query: 376 CATRNR-TVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDL 434 A + VP+C+TF F +R++A+SE+ + +H + +GEDGP+ +E L Sbjct: 433 IALHSPGFVPYCATFFVFTDYMRGAMRISALSEAGVIYVMTHDSIGLGEDGPTHQPIEHL 492 Query: 435 AMFRSVPTSTVFYPSDGVATEKAVELAA-NTKGICFIRTSRPENAIIYNNN-EDFQVGQA 492 FR++P + P+DG T A ++A N K + SR + + + E + G Sbjct: 493 VSFRAMPNILMLRPADGNETAGAYKVAVLNRKRPSILALSRQKLPHLPGTSIEGVEKGGY 552 Query: 493 KVVLKSKD--DQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSAR 550 + S + V+G G L A AA+ L+KE +RV+ + + D + Sbjct: 553 TISDNSTGNKPDLIVMGTGSELEIAAKAADELRKEGKTVRVVSFVSWELFDEQ------- 605 Query: 551 ATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTH----------LAVNRVPRSGKPAE 600 D Y E + AV++ + E G T+ + +++ S Sbjct: 606 ---------SDEYKESVLPAAVTARISIEAGSTLGWQKYVGAQGKAIGIDKFGASAPAGT 656 Query: 601 LLKMFGIDRDAIAQAVR 617 + K +GI ++I A + Sbjct: 657 IYKEYGITVESIIAAAK 673 >4XEU-A nrPDB Length = 673 Score = 648 bits (1672), Expect = 0.0, Method: Composition-based stats. Identities = 163/682 (23%), Positives = 273/682 (40%), Gaps = 92/682 (13%) Query: 12 LQALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRF 71 + + ++ AN +R S+ A A SGHP + A+I VL+ M++ +P+ + DRF Sbjct: 9 MPSRRERANAIRALSMDAVQKANSGHPGAPMGMADIAEVLWRDYMQHNPSNPQWANRDRF 68 Query: 72 VLSKGHAAPILYAVWAEAGF-LAEAELLNLRKISSDLDGHPV-PKQAFTDVATGSLGQGL 129 VLS GH + ++Y++ G+ L +L N R+++S GHP A + TG LGQG+ Sbjct: 69 VLSNGHGSMLIYSLLHLTGYDLGIEDLKNFRQLNSRTPGHPEYGYTAGVETTTGPLGQGI 128 Query: 130 GAACGMAYTGKY----FDKA-----SYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVA 180 A GMA K F++ + Y LGDG + EG E + A +L+ L+A Sbjct: 129 ANAVGMALAEKVLAAQFNRDGHAVVDHYTYAFLGDGCMMEGISHEVASLAGTLRLNKLIA 188 Query: 181 ILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAII-VDGHSVEELCKAFGQAK--HQPTA 237 D N + D KR EA+GW I VDGH +E+ A A+ QPT Sbjct: 189 FYDDNGISIDGEVHG-WFTDDTPKRFEAYGWQVIRNVDGHDADEIKTAIDTARKSDQPTL 247 Query: 238 IIAKTFKGRGITGVEDKESWHGKPLPKNM-------------AEQIIQEIYSQIQSKKK- 283 I KT G G + KE HG PL + +I +IY++ +K+ Sbjct: 248 ICCKTVIGFGSPNKQGKEECHGAPLGADEIAATRAALGWEHAPFEIPAQIYAEWDAKETG 307 Query: 284 -------------ILATPPQEDAPSVDIANIRMPSLPSYKV----------GDKIATRKA 320 A P+ A + +P+ + K G+ IA+RKA Sbjct: 308 AAQEAEWNKRFAAYQAAHPELAAELLRRLKGELPADFAEKAAAYVADVANKGETIASRKA 367 Query: 321 YGQALAKLGHASDRIIALDGDTKNSTFS------EIFKKEHPDRFIECYIAEQNMVSIAV 374 AL G ++ D S + + + ++ + E M +I Sbjct: 368 SQNALNAFGPLLPELLGGSADLAGSNLTLWKGCKGVSADDAAGNYVFYGVREFGMSAIMN 427 Query: 375 GCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALEDL 434 G A +P+ +TF F A + +RM+A+ + + +H + +GEDGP+ +E L Sbjct: 428 GVALHGGFIPYGATFLIFMEYARNAVRMSALMKQRVLYVFTHDSIGLGEDGPTHQPIEQL 487 Query: 435 AMFRSVPTSTVFYPSDGVATEKAVELAANT-KGICFI---RTSRPENAIIYNNNEDFQVG 490 A R P + P+D V + A + A G + R + P A D + Sbjct: 488 ASLRLTPNLDTWRPADAVESAVAWKHAIERADGPSALIFSRQNLPHQARDVAQVAD--IA 545 Query: 491 QAKVVLKS--KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDS 548 + VLK + ++ +I G + A+ A + L ++ +RV+ +++ Sbjct: 546 RGGYVLKDCEGEPELILIATGSEVGLAVQAYDKLSEQGRKVRVVSMPCTSVYEQQ----- 600 Query: 549 ARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTH----------LAVNRVPRSGKP 598 ++ Y + + V + + E + + S Sbjct: 601 -----------DESYKQSVLPVEVGARIAIEAAHADYWYKYVGLDGRIIGMTSFGESAPA 649 Query: 599 AELLKMFGIDRDAIAQAVRGLI 620 L + FG D + L+ Sbjct: 650 PALFEHFGFTLDNVLAVAEELL 671 >1GPU-A nrPDB Length = 680 Score = 638 bits (1645), Expect = 0.0, Method: Composition-based stats. Identities = 173/671 (25%), Positives = 276/671 (41%), Gaps = 81/671 (12%) Query: 16 KDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSK 75 K + +RI ++ + A SGHP + A VL+ MR +P + DRFVLS Sbjct: 9 KLAVSTIRILAVDTVSKANSGHPGAPLGMAPAAHVLW-SQMRMNPTNPDWINRDRFVLSN 67 Query: 76 GHAAPILYAVWAEAGF-LAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACG 134 GHA +LY++ G+ L+ +L R++ S GHP + +V TG LGQG+ A G Sbjct: 68 GHAVALLYSMLHLTGYDLSIEDLKQFRQLGSRTPGHPEFELPGVEVTTGPLGQGISNAVG 127 Query: 135 MAYT---------GKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185 MA F + Y LGDG L EG EA + A KL NL+AI D N Sbjct: 128 MAMAQANLAATYNKPGFTLSDNYTYVFLGDGCLQEGISSEASSLAGHLKLGNLIAIYDDN 187 Query: 186 RLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDG--HSVEELCKAFGQAK---HQPTAIIA 240 ++ + D+ KR EA+GW + V+ + + KA QAK +PT I Sbjct: 188 KITIDGATSISFDEDV-AKRYEAYGWEVLYVENGNEDLAGIAKAIAQAKLSKDKPTLIKM 246 Query: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQ--------------IIQEIYSQIQ------- 279 T G G S HG PL + +Q + QE+Y Q Sbjct: 247 TTTIGYGSLH-AGSHSVHGAPLKADDVKQLKSKFGFNPDKSFVVPQEVYDHYQKTILKPG 305 Query: 280 ----SKKKILATPPQEDAPSV-----DIANIRMPS-----LPSYKVGDK-IATRKAYGQA 324 +K L + Q+ P + + ++P+ LP+Y D +ATRK Sbjct: 306 VEANNKWNKLFSEYQKKFPELGAELARRLSGQLPANWESKLPTYTAKDSAVATRKLSETV 365 Query: 325 LAKLGHASDRIIALDGDTKNSTFS---EIFKKEHP--------DRFIECYIAEQNMVSIA 373 L + + +I D S + E + P R+I I E M +I Sbjct: 366 LEDVYNQLPELIGGSADLTPSNLTRWKEALDFQPPSSGSGNYSGRYIRYGIREHAMGAIM 425 Query: 374 VGCATRNRTV-PFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALE 432 G + P+ TF F + A +R++A+S + +H + +GEDGP+ +E Sbjct: 426 NGISAFGANYKPYGGTFLNFVSYAAGAVRLSALSGHPVIWVATHDSIGVGEDGPTHQPIE 485 Query: 433 DLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENAIIYNNNEDFQVGQA 492 LA FRS+P V+ P+DG A + + +K I +N + + Sbjct: 486 TLAHFRSLPNIQVWRPADGNEVSAAYKNSLESKHTPSIIALSRQNLPQLEGSSIESASKG 545 Query: 493 KVVLKS-KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILD--SA 549 VL+ + + ++ G + ++ AA+ L + I RV+ D++ + S Sbjct: 546 GYVLQDVANPDIILVATGSEVSLSVEAAKTLAAKNIKARVVSLPDFFTFDKQPLEYRLSV 605 Query: 550 RATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLKMFGIDR 609 I++VE +++ G+ ++R SGK E+ K FG Sbjct: 606 LPDNVPIMSVE----------VLATTCWGK--YAHQSFGIDRFGASGKAPEVFKFFGFTP 653 Query: 610 DAIAQAVRGLI 620 + +A+ + I Sbjct: 654 EGVAERAQKTI 664 >3RIM-A nrPDB Length = 700 Score = 553 bits (1424), Expect = e-158, Method: Composition-based stats. Identities = 162/680 (23%), Positives = 256/680 (37%), Gaps = 110/680 (16%) Query: 19 ANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHA 78 + +R+ + A G+GHP + S A + LF TMR+ D DRFVLS GH+ Sbjct: 27 VDTIRVLAADAVQKVGNGHPGTAMSLAPLAYTLFQRTMRHDPSDTHWLGRDRFVLSAGHS 86 Query: 79 APILYAVWAEAGF-LAEAELLNLRKISSDLDGHPVPKQ-AFTDVATGSLGQGLGAACGMA 136 + LY GF L +++ +LR S GHP + ++ TG LGQGL +A GMA Sbjct: 87 SLTLYIQLYLGGFGLELSDIESLRTWGSKTPGHPEFRHTPGVEITTGPLGQGLASAVGMA 146 Query: 137 YTGKY----FDKA--------SYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDI 184 +Y FD + +Y + DG++ EG EA + A++ +L NL+ D Sbjct: 147 MASRYERGLFDPDAEPGASPFDHYIYVIASDGDIEEGVTSEASSLAAVQQLGNLIVFYDR 206 Query: 185 NRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGH----SVEELCKAFGQAKHQPTAIIA 240 N++ D + D R A+GWH V+G +EE +P+ I Sbjct: 207 NQISIEDDTNIALCED-TAARYRAYGWHVQEVEGGENVVGIEEAIANAQAVTDRPSFIAL 265 Query: 241 KTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIY----SQIQSKKKILA---------- 286 +T G + D HG L + + + + Q ++ +L Sbjct: 266 RTVIGYPAPNLMDTGKAHGAALGDDEVAAVKKIVGFDPDKTFQVREDVLTHTRGLVARGK 325 Query: 287 ---------------TPPQEDAPSVDIANIRMPS-----LPSYKVGDK-IATRKAYGQAL 325 P+ A + ++P LP ++ G K +ATR A G L Sbjct: 326 QAHERWQLEFDAWARREPERKALLDRLLAQKLPDGWDADLPHWEPGSKALATRAASGAVL 385 Query: 326 AKLGHASDRIIALDGDTKNSTFS-----------EIFKKEHP----DRFIECYIAEQNMV 370 + LG + D S + I KE+ R + + E M Sbjct: 386 SALGPKLPELWGGSADLAGSNNTTIKGADSFGPPSISTKEYTAHWYGRTLHFGVREHAMG 445 Query: 371 SIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMA 430 +I G T + TF F +R+AA+ + + +H + +GEDGP+ Sbjct: 446 AILSGIVLHGPTRAYGGTFLQFSDYMRPAVRLAALMDIDTIYVWTHDSIGLGEDGPTHQP 505 Query: 431 LEDLAMFRSVPTSTVFYPSDGVATEKAVEL------AANTKGICFIRTSRPENAIIYNNN 484 +E L+ R++P +V P+D T A + G+ R P + + Sbjct: 506 IEHLSALRAIPRLSVVRPADANETAYAWRTILARRNGSGPVGLILTRQGVP----VLDGT 561 Query: 485 EDFQVGQAKVVLK-------SKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLD---- 533 + V + VL ++ V +I G + A+AA LL I RV+ Sbjct: 562 DAEGVARGGYVLSDAGGLQPGEEPDVILIATGSEVQLAVAAQTLLADNDILARVVSMPCL 621 Query: 534 -PFTIKPLDR-KLILD---SARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLA 588 F +P + +L SAR + H G GE VS GE Sbjct: 622 EWFEAQPYEYRDAVLPPTVSARVAVEAGVAQCWHQLVGDTGEIVSIEHYGE--------- 672 Query: 589 VNRVPRSGKPAELLKMFGID 608 S L + +G Sbjct: 673 ------SADHKTLFREYGFT 686 >2O1S-A nrPDB Length = 621 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 139/639 (21%), Positives = 252/639 (39%), Gaps = 76/639 (11%) Query: 13 QALKDTANRLRISSIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFV 72 ++L + LR + + + + SGH S E+ L H + D+ + Sbjct: 26 ESLPKLCDELRRYLLDSVSRS-SGHFASGLGTVELTVAL--HYVYNTPF-------DQLI 75 Query: 73 LSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQ----- 127 GH A Y G ++ +R+ HP P + ++ S+G Sbjct: 76 WDVGHQA---YPHKILTGR--RDKIGTIRQKGGL---HPFPWRGESEYDVLSVGHSSTSI 127 Query: 128 --GLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDIN 185 G+G A GK + R C++GDG ++ G +EAM A + D LV IL+ N Sbjct: 128 SAGIGIAVAAEKEGK-----NRRTVCVIGDGAITAGMAFEAMNHAGDIRPDMLV-ILNDN 181 Query: 186 RLGQSDP-APLQHQM------DIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAI 238 + S+ L + + +Y E G + ++EL K +H + Sbjct: 182 EMSISENVGALNNHLAQLLSGKLYSSLRE--GGKKVFSGVPPIKELLKR--TEEHIKGMV 237 Query: 239 IAKTF---KGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQED--- 292 + T G G D G + + I +KK P ++D Sbjct: 238 VPGTLFEELGFNYIGPVDGHDVLGLITTLKNMRDLKGPQFLHIMTKKGRGYEPAEKDPIT 297 Query: 293 ---APSVDIANIRMP----SLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNS 345 P D ++ +P LPSY K +G L + ++++A+ + Sbjct: 298 FHAVPKFDPSSGCLPKSSGGLPSYS--------KIFGDWLCETAAKDNKLMAITPAMREG 349 Query: 346 TFSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQI-RMAA 404 + F ++ PDR+ + IAEQ+ V+ A G A P + ++ F RA+DQ+ A Sbjct: 350 SGMVEFSRKFPDRYFDVAIAEQHAVTFAAGLAIGGYK-PIVAIYSTFLQRAYDQVLHDVA 408 Query: 405 ISESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAAN- 463 I + + G+ +G DG + DL+ R +P + PSD + + + Sbjct: 409 IQKLPVLFAIDRAGI-VGADGQTHQGAFDLSYLRCIPEMVIMTPSDENECRQMLYTGYHY 467 Query: 464 TKGICFIRTSRPENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLK 523 G +R R NA+ ++ K ++K + +++ ++ G + EA AE L Sbjct: 468 NDGPSAVRYPR-GNAVGVELTPLEKLPIGKGIVKRRGEKLAILNFGTLMPEAAKVAESLN 526 Query: 524 KEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVG-EPGI 582 ++D +KPLD LIL+ A A+ ++TVE++ GG G V+ ++ + Sbjct: 527 AT-----LVDMRFVKPLDEALILEMA-ASHEALVTVEENAIMGGAGSGVNEVLMAHRKPV 580 Query: 583 TVTHLAVNR-VPRSGKPAELLKMFGIDRDAIAQAVRGLI 620 V ++ + G E+ G+D + ++ + Sbjct: 581 PVLNIGLPDFFIPQGTQEEMRAELGLDAAGMEAKIKAWL 619 >2O1X-A nrPDB Length = 629 Score = 310 bits (793), Expect = 1e-84, Method: Composition-based stats. Identities = 128/637 (20%), Positives = 225/637 (35%), Gaps = 46/637 (7%) Query: 1 MESYHKPDQQKLQALKDTANRLRISSIQATTAAGSG--HPTSCCSAAEIMAVLFFHTMRY 58 ++ H P K + + + G H S A +I+ L H + Sbjct: 13 LDQIHGPKDLKRLSREQLPALTEELRGEIVRVCSRGGLHLASSLGAVDIITAL--HYVLD 70 Query: 59 KSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLDGHPVPKQAFT 118 DR + GH A YA G ++ +++K + G K + + Sbjct: 71 SP-------RDRILFDVGHQA---YAHKILTGR--RDQMADIKKEG-GISG--FTKVSES 115 Query: 119 DVATGSLGQG---LGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKL 175 + ++G L A GMA K + V ++GDG L+ G A+ Sbjct: 116 EHDAITVGHASTSLTNALGMALARDAQGKDFH-VAAVIGDGSLTGGMALAALNTIGDMGR 174 Query: 176 DNLVAILDINRLGQSDP-APLQHQMDIYQKRC-----EAFGWHAIIVDGHSVEELCKAFG 229 L+ +L+ N + S+ + M Q + E G A+ + + Sbjct: 175 KMLI-VLNDNEMSISENVGAMNKFMRGLQVQKWFQEGEGAGKKAVEAVSKPLADFMSRAK 233 Query: 230 QAKHQ---PTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILA 286 + P ++ G G D + + I + K Sbjct: 234 NSTRHFFDPASVNPFAAMGVRYVGPVDGHNVQELVWLLERLVDLDGPTILHIVTTKGKGL 293 Query: 287 TPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQALAKLGHASDRIIALDGDTKNST 346 + + D P+ Y + A+G+A+ + R + + + Sbjct: 294 SYAEADPIYWHGPAKFDPATGEYVPSSAYSWSAAFGEAVTEWAKTDPRTFVVTPAMREGS 353 Query: 347 FSEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQI-RMAAI 405 F + HP R+++ IAE+ V+ A G A + P + ++ F RA+DQ+ AI Sbjct: 354 GLVEFSRVHPHRYLDVGIAEEVAVTTAAGMALQGMR-PVVAIYSTFLQRAYDQVLHDVAI 412 Query: 406 SESNINLCGSHCGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTK 465 N+ C G+ +G DG + + DL+ RS+P + P D ++ A Sbjct: 413 EHLNVTFCIDRAGI-VGADGATHNGVFDLSFLRSIPGVRIGLPKDAAELRGMLKYAQTHD 471 Query: 466 GICFIRTSRPENA-IIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKK 524 G IR R A + D + G+ + + D V ++ G L AL AAE L Sbjct: 472 GPFAIRYPRGNTAQVPAGTWPDLKWGEWERL--KGGDDVVILAGGKALDYALKAAEDLP- 528 Query: 525 EKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITV 584 + V++ +KPLD +++ + ++TVED+ GG G AV A+ Sbjct: 529 ---GVGVVNARFVKPLDEEMLRE-VGGRARALITVEDNTVVGGFGGAVLEALNSMNLHPT 584 Query: 585 THLAV--NRVPRSGKPAELLKMFGIDRDAIAQAVRGL 619 + + + GID AI + L Sbjct: 585 VRVLGIPDEFQEHATAESVHARAGIDAPAIRTVLAEL 621 >6CFO-B nrPDB Length = 341 Score = 255 bits (650), Expect = 6e-68, Method: Composition-based stats. Identities = 66/326 (20%), Positives = 120/326 (36%), Gaps = 26/326 (7%) Query: 314 KIATRKAYGQALAKLGHASDRIIALDGDTKNSTF-----SEIFKKEHPDRFIECYIAEQN 368 ++ R A Q + + +++ L + ++KK R I+ I+E Sbjct: 14 QVTVRDAINQGMDEELERDEKVFLLGEEVAQYDGAYKVSRGLWKKYGDKRIIDTPISEMG 73 Query: 369 MVSIAVGCATRNRTVPFCSTFAAFFT-RAFDQIRMAAISESNINLCGSHCGVSIGEDGP- 426 IAVG A P C F+ +A DQ+ +A + G V I GP Sbjct: 74 FAGIAVGAAMAGLR-PICEFMTFNFSMQAIDQVINSA--AKTYYMSGGLQPVPIVFRGPN 130 Query: 427 -------SQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFI-----RTSR 474 +Q + A + P V P + + ++ A + Sbjct: 131 GASAGVAAQHSQCFAAWYGHCPGLKVVSPWNSEDAKGLIKSAIRDNNPVVVLENELMYGV 190 Query: 475 PENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDP 534 P ++DF + K ++ + +TV+ + L AA +L KE + V++ Sbjct: 191 PFEFPPEAQSKDFLIPIGKAKIERQGTHITVVSHSRPVGHCLEAAAVLSKEGVECEVINM 250 Query: 535 FTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPR 594 TI+P+D + I S T ++TVE + + G+G + + ++ P RV Sbjct: 251 RTIRPMDMETIEASVMKTN-HLVTVEGGWPQFGVGAEICARIMEGPAFNFLDAPAVRVTG 309 Query: 595 SGKPAELLKMFGIDRDAIAQAVRGLI 620 + P K+ D V+ +I Sbjct: 310 ADVPMPYAKIL---EDNSIPQVKDII 332 >3LQ2-A nrPDB Length = 886 Score = 225 bits (573), Expect = 4e-59, Method: Composition-based stats. Identities = 63/233 (27%), Positives = 98/233 (42%), Gaps = 22/233 (9%) Query: 12 LQALKDTANRLRISSIQATTAAGS------GHPTSCCSAAEIMAVLFFHTMRYKSQDPRN 65 L+ + + +R ++I A GH S S+A I V F H R +++ Sbjct: 75 LELERRIRSAIRWNAIMTVLRASKKDLELGGHMASFQSSATIYDVCFNHFFRARNEQ--- 131 Query: 66 PHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRK--ISSDLDGHPVPK--QAFTDVA 121 V +GH +P +YA G L + +L N R+ + L +P PK F Sbjct: 132 -DGGDLVYFQGHISPGVYARAFLEGRLTQEQLDNFRQEVHGNGLSSYPHPKLMPEFWQFP 190 Query: 122 TGSLGQGLGAACGMAYTGKYF------DKASYRVYCLLGDGELSEGSVWEAMAFASIYKL 175 T S+G G A A KY D + VY LGDGE+ A+ A+ KL Sbjct: 191 TVSMGLGPIGAIYQAKFLKYLEHRGLKDTSKQTVYAFLGDGEMDAPESKGAITIATREKL 250 Query: 176 DNLVAILDINRLGQSDPAPLQHQ-MDIYQKRCEAFGWHAI-IVDGHSVEELCK 226 DNLV +++ N P + ++ + E GW+ I ++ G +EL + Sbjct: 251 DNLVFVINCNLQRLDGPVTGNGKIINELEGIFEGAGWNVIKVMWGSRWDELLR 303 >1IK6-A nrPDB Length = 369 Score = 215 bits (548), Expect = 4e-56, Method: Composition-based stats. Identities = 85/364 (23%), Positives = 140/364 (38%), Gaps = 54/364 (14%) Query: 290 QEDAPSVDIANIRMPSLPSYKVGDKIA-------TRKAYGQALAKLGHASDRIIALDGDT 342 + A + ++ P L + +A KA AL + +R++ L D Sbjct: 19 ETAAAKFERNHMDSPDLGTDDDDKMVAGVVMMANMAKAINMALHEEMERDERVVVLGEDV 78 Query: 343 --KNSTF---SEIFKKEHPDRFIECYIAEQNMVSIAVGCATRNRTVPFCSTFAAFFTRAF 397 K F ++++ P+R I+ + E ++ A+G A F F Sbjct: 79 GKKGGVFLVTEGLYERFGPERVIDTPLNEGGILGFAMGMAMAGLKPVAEIQFVDFIWLGA 138 Query: 398 DQIRMAAISESNINLCGSH-------CGVSIGEDGPSQMALEDLAMFRSVPTSTVFYPSD 450 D++ + I++ G++ V G G + A+F P V PS Sbjct: 139 DEL-LNHIAKLRYRSGGNYKAPLVVRTPVGSGTRGGLYHSNSPEAIFVHTPGLVVVMPS- 196 Query: 451 GVATEKAVELAANTKGI--CFIRTSRP----ENAIIYNNNE------DFQVGQAKVVLKS 498 N KG+ IR P E I+Y D+ V K + Sbjct: 197 ---------TPYNAKGLLKAAIRGDDPVVFLEPKILYRAPREEVPEGDYVVEIGKARVAR 247 Query: 499 KDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILT 558 + D VT++ G +H+AL AAE + K ++ V+D T+ PLD +L S T GR++ Sbjct: 248 EGDDVTLVTYGAVVHKALEAAE---RVKASVEVVDLQTLNPLDFDTVLKSVSKT-GRLII 303 Query: 559 VEDHYYEGGIGEAVSSAVVGEPGI-----TVTHLAVNRVPRSGKPAELLKMFGIDRDAIA 613 D GG+G V A+V E + V LA VP+S A+ + + I Sbjct: 304 AHDSPKTGGLGAEV-RALVAEKALDRLTAPVIRLAGPDVPQSPIAADAA--YAPTVERII 360 Query: 614 QAVR 617 +A+ Sbjct: 361 KAIE 364 >1UMC-B nrPDB Length = 324 Score = 206 bits (525), Expect = 2e-53, Method: Composition-based stats. Identities = 69/321 (21%), Positives = 124/321 (38%), Gaps = 25/321 (7%) Query: 319 KAYGQALAKLGHASDRIIALDGDT--KNSTF---SEIFKKEHPDRFIECYIAEQNMVSIA 373 +A +AL + R++ L D + F + +K PDR ++ ++E +V A Sbjct: 8 QALNRALDEEMAKDPRVVVLGEDVGKRGGVFLVTEGLLQKYGPDRVMDTPLSEAAIVGAA 67 Query: 374 VGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSHCGVSIGEDGPSQMALED 433 +G A FA + FDQ+ ++ +++ G + PS + Sbjct: 68 LGMAAHGLRPVAEIQFADYIFPGFDQL-VSQVAKLRYR-SGGQFTAPLVVRMPSGGGVRG 125 Query: 434 LAMFRSVPTSTVFYPSDGVATEKAVELAANTKGI--CFIRTSRP----ENAIIYNN---- 483 P + F + G+ AV + KG+ IR P E +Y + Sbjct: 126 GHHHSQSPEAH-FVHTAGLKV-VAVSTPYDAKGLLKAAIRDEDPVVFLEPKRLYRSVKEE 183 Query: 484 --NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLD 541 ED+ + K L+ + +T+I G + E L AA L K ++ VLD T+ P D Sbjct: 184 VPEEDYTLPIGKAALRREGKDLTLICYGTVMPEVLQAAAELAKAGVSAEVLDLRTLMPWD 243 Query: 542 RKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAEL 601 + +++S T GR++ V D V++ + E + + RV P Sbjct: 244 YEAVMNSVAKT-GRVVLVSDAPRHASFVSEVAATI-AEDLLDMLLAPPIRVTGFDTPYPY 301 Query: 602 L--KMFGIDRDAIAQAVRGLI 620 K++ I A + + Sbjct: 302 AQDKLYLPTVTRILNAAKRAL 322 >3DV0-B nrPDB Length = 325 Score = 164 bits (415), Expect = 9e-41, Method: Composition-based stats. Identities = 64/314 (20%), Positives = 111/314 (35%), Gaps = 37/314 (11%) Query: 314 KIATRKAYGQALAKLGHASDRIIALDGDT--KNSTFS---EIFKKEHPDRFIECYIAEQN 368 ++ +A AL ++ D F + + DR + +AE Sbjct: 3 QMTMVQAITDALRIELKNDPNVLIFGEDVGVNGGVFRATEGLQAEFGEDRVFDTPLAESG 62 Query: 369 MVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGSH-------CGVSI 421 + +A+G A + F F D I ++ G + Sbjct: 63 IGGLAIGLALQGFRPVPEIQFFGFVYEVMDSI-CGQMARIRYRTGGRYHMPITIRSPFGG 121 Query: 422 GEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGI--CFIRTSRP---- 475 G P + + P V PS + KG+ IR + P Sbjct: 122 GVHTPELHSDSLEGLVAQQPGLKVVIPS----------TPYDAKGLLISAIRDNDPVIFL 171 Query: 476 ENAIIYNN------NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINI 529 E+ +Y + ++ + K +K + +T+I G +HE+L AA L+KE I+ Sbjct: 172 EHLKLYRSFRQEVPEGEYTIPIGKADIKREGKDITIIAYGAMVHESLKAAAELEKEGISA 231 Query: 530 RVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAV 589 V+D T++PLD + I+ S T GR + V++ + GI V + + E I V Sbjct: 232 EVVDLRTVQPLDIETIIGSVEKT-GRAIVVQEAQRQAGIAANVVAEI-NERAILSLEAPV 289 Query: 590 NRVPRSGKPAELLK 603 RV + Sbjct: 290 LRVAAPDTVYPFAQ 303 >1QS0-B nrPDB Length = 338 Score = 145 bits (366), Expect = 5e-35, Method: Composition-based stats. Identities = 63/346 (18%), Positives = 111/346 (32%), Gaps = 46/346 (13%) Query: 311 VGDKIATRKAYGQALAKLGHASDRIIALDGDTK--NSTFS---EIFKKEHPDRFIECYIA 365 + +A A+ + D ++ D F + K R + I+ Sbjct: 1 ATTTMTMIQALRSAMDVMLERDDNVVVYGQDVGYFGGVFRCTEGLQTKYGKSRVFDAPIS 60 Query: 366 EQNMVSIAVGCATRNRTVPFCSTFAAFFTRAFDQIRMAAISESNINLCGS-------HCG 418 E +V AVG FA +F A DQI ++ ++ G Sbjct: 61 ESGIVGTAVGMGAYGLRPVVEIQFADYFYPASDQI-VSEMARLRYRSAGEFIAPLTLRMP 119 Query: 419 VSIGEDGPSQMALEDLAMFRSVPTSTVFYPSDGVATEKAVELAANTKGICFIRTSRPENA 478 G G + AMF V PS+ + + + E Sbjct: 120 CGGGIYGGQTHSQSPEAMFTQVCGLRTVMPSNPYDAKGLLIASIECDDPVIFL----EPK 175 Query: 479 IIYNNNED----------------------FQVGQAKVVLKSKDDQVTVIGAGVTLHEAL 516 +YN D + V K + + V+V+ G T++ A Sbjct: 176 RLYNGPFDGHHDRPVTPWSKHPHSAVPDGYYTVPLDKAAITRPGNDVSVLTYGTTVYVAQ 235 Query: 517 AAAELLKKEKINIRVLDPFTIKPLDRKLILDSARATKGRILTVEDHYYEGGIGEAVSSAV 576 AAE ++ V+D ++ PLD I++S + T GR + V + G G + S + Sbjct: 236 VAAEE---SGVDAEVIDLRSLWPLDLDTIVESVKKT-GRCVVVHEATRTCGFGAELVS-L 290 Query: 577 VGEPGITVTHLAVNRVPRSGKPAELLKMFGI--DRDAIAQAVRGLI 620 V E + RV P + + + A++ ++ Sbjct: 291 VQEHCFHHLEAPIERVTGWDTPYPHAQEWAYFPGPSRVGAALKKVM 336 >1X7Z-A nrPDB Length = 400 Score = 52.5 bits (124), Expect = 5e-07, Method: Composition-based stats. Identities = 39/158 (24%), Positives = 62/158 (39%), Gaps = 12/158 (7%) Query: 91 FLAEAELLNLRKISSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVY 150 + ++L R+ + H K+ + L + A G AY K A+ V Sbjct: 134 YGNISDLGKGRQ----MPVHYGCKERHFVTISSPLATQIPQAVGAAYAAKR-ANANRVVI 188 Query: 151 CLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFG 210 C G+G SEG FA+ + ++ N S P Q++ D R +G Sbjct: 189 CYFGEGAASEGDAHAGFNFAATLEC-PIIFFCRNNGYAISTPTSEQYRGDGIAARGPGYG 247 Query: 211 WHAIIVDGHSVEELCKAFGQAK------HQPTAIIAKT 242 +I VDG+ V + A +A+ +QP I A T Sbjct: 248 IMSIRVDGNDVFAVYNATKEARRRAVAENQPFLIEAMT 285 >5B46-A nrPDB Length = 628 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 24/139 (17%), Positives = 53/139 (38%), Gaps = 17/139 (12%) Query: 484 NEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRK 543 D ++ + + V D + ++ G L A E L K+ I ++ P + Sbjct: 496 TADKEIPEEQRVNIVGDADIVLLTWGSPKGAILDAMEELSKDGIKTMMVQVKMFNPYPKN 555 Query: 544 LILDSARATKGRILTVEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNRVPRSGKPAELLK 603 L + + K +I+ VE++Y G V + G + +G+P Sbjct: 556 L-MKKILSGKSKIIAVENNY--NAQGAEVLAEKTGIFATNYI------LKWTGRP----- 601 Query: 604 MFGIDRDAIAQAVRGLITK 622 I R+ + + ++ ++ + Sbjct: 602 ---ITREEVIEGIKKILER 617 >3EXI-A nrPDB Length = 382 Score = 42.9 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 40/212 (18%), Positives = 72/212 (33%), Gaps = 24/212 (11%) Query: 123 GSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAIL 182 LG G+ AC ++ L GDG ++G ++EA A+++KL + I Sbjct: 163 VPLGAGIALAC-------KYNGKDEVCLTLYGDGAANQGQIFEAYNMAALWKL-PCIFIC 214 Query: 183 DINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQPTAIIAKT 242 + NR G Y KR + + G V+ + + + A ++ Sbjct: 215 ENNRYGMGTSVERAAASTDYYKRGD-------FIPGLRVDGMDILCVREATRFAAAYCRS 267 Query: 243 FKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIR 302 KG I +HG + Y + +++ + + N Sbjct: 268 GKG-PILMELQTYRYHGHSMSD------PGVSYRTREEIQEVRSKSDPIMLLKDRMVNSN 320 Query: 303 MPSLPSYKVGDKIATRKAYGQALAKLGHASDR 334 + S+ K D + RK A A+ A Sbjct: 321 LASVEELKEID-VEVRKEIEDA-AQFATADPE 350 >1UM9-A nrPDB Length = 367 Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 34/184 (18%), Positives = 58/184 (31%), Gaps = 20/184 (10%) Query: 104 SSDLDGHPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSV 163 + HP K + + A G A + K + C GDG SEG Sbjct: 125 GRQMPEHPGSKALNFFTVASPIASHVPPAAGAAISMKLL-RTGQVAVCTFGDGATSEGDW 183 Query: 164 WEAMAFASIYKLDNLVAILDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEE 223 + + FA++ V I + N S Q + AFG +VDG V Sbjct: 184 YAGINFAAVQG-APAVFIAENNFYAISVDYRHQTHSPTIADKAHAFGIPGYLVDGMDVLA 242 Query: 224 ----LCKAFGQAK--HQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQ 277 + +A +A+ P+ + + S + + +E + Sbjct: 243 SYYVVKEAVERARRGEGPSLVELR-------VYRYGPHSS-----ADDDSRYRPKEEVAF 290 Query: 278 IQSK 281 + K Sbjct: 291 WRKK 294 >3DVA-A nrPDB Length = 369 Score = 40.2 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 45/202 (22%), Positives = 73/202 (36%), Gaps = 18/202 (8%) Query: 127 QGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFASIYKLDNLVAILDINR 186 Q G A G+ GK +Y GDG S+G +E + FA +K + ++ NR Sbjct: 151 QAAGVALGLKMRGKKAVAITYT-----GDGGTSQGDFYEGINFAGAFK-APAIFVVQNNR 204 Query: 187 LGQSDPAPLQHQMDIYQKRCEAFGWHAIIVDGHSVEELCKAFGQAKHQ------PTAIIA 240 S P Q ++ A G I VDG + A A+ + PT I Sbjct: 205 FAASTPVEKQTVAKTLAQKAVAAGIPGIQVDGMDPLAVYAAVKAARERAINGEGPTLIET 264 Query: 241 KTFK-GRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDA-----P 294 F+ G +D + K L A++ + + K + + + + Sbjct: 265 LCFRYGPHTMSGDDPTRYRSKELENEWAKKDPLVRFRKFLEAKGLWSEEEENNVIEQAKE 324 Query: 295 SVDIANIRMPSLPSYKVGDKIA 316 + A + P KV D I+ Sbjct: 325 EIKEAIKKADETPKQKVTDLIS 346 >3UIM-A nrPDB Length = 326 Score = 35.9 bits (81), Expect = 0.057, Method: Composition-based stats. Identities = 26/153 (16%), Positives = 48/153 (31%), Gaps = 23/153 (15%) Query: 454 TEKAVELAANTKGICFIRT-SRPENAIIYNNNEDFQVGQAK-----VVLKSKDDQVTVIG 507 TE+ + G RPE+ + + ++ + D ++ Sbjct: 100 TERLLVYPYMANGSVASCLRERPESQPPLDWPKRQRIALGSARGLAYLHDHCDPKII--- 156 Query: 508 AGVTLHEALAAAELLKKEKINIRVLDPFTIKPLDRK--LILDSARATKGRIL-------T 558 H + AA +L E+ V D K +D K + + R T G I Sbjct: 157 -----HRDVKAANILLDEEFEAVVGDFGLAKLMDYKDTHVTTAVRGTIGHIAPEYLSTGK 211 Query: 559 VEDHYYEGGIGEAVSSAVVGEPGITVTHLAVNR 591 + G G + + G+ + LA + Sbjct: 212 SSEKTDVFGYGVMLLELITGQRAFDLARLANDD 244 >3OIC-A nrPDB Length = 258 Score = 35.2 bits (79), Expect = 0.083, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 36/93 (38%) Query: 476 ENAIIYNNNEDFQVGQAKVVLKSKDDQVTVIGAGVTLHEALAAAELLKKEKINIRVLDPF 535 +N VG+A + +++ VI + AL AE ++K + + V+ Sbjct: 3 QNKCALVTGSSRGVGKAAAIRLAENGYNIVINYARSKKAALETAEEIEKLGVKVLVVKAN 62 Query: 536 TIKPLDRKLILDSARATKGRILTVEDHYYEGGI 568 +P K + T GR+ ++ G + Sbjct: 63 VGQPAKIKEMFQQIDETFGRLDVFVNNAASGVL 95 >4Q9D-A nrPDB Length = 545 Score = 32.9 bits (73), Expect = 0.47, Method: Composition-based stats. Identities = 29/144 (20%), Positives = 47/144 (32%), Gaps = 16/144 (11%) Query: 110 HPVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAF 169 HP +F +G +G G+ AA G+A G V +GDG +A+ Sbjct: 393 HP---ASFFATGSGGIGWGVPAAVGIAL-GDRARGVDRTVVATIGDGSFQYSI--QAIWT 446 Query: 170 ASIYKLDNLVAILDINRLGQSDP-APLQHQMD---------IYQKRCEAFGWHAIIVDGH 219 A+ +KL + +L A L+ + FG V+ Sbjct: 447 AAQHKLPIVFVVLRNGEYAILKSFADLEKTPNVPGLQLPGLDISSIAAGFGCRTATVEST 506 Query: 220 SVEELCKAFGQAKHQPTAIIAKTF 243 + E PT ++ T Sbjct: 507 DMLEAELKTALQADGPTVLVVPTL 530 >6GUA-A nrPDB Length = 822 Score = 32.9 bits (73), Expect = 0.49, Method: Composition-based stats. Identities = 31/193 (16%), Positives = 51/193 (26%), Gaps = 22/193 (11%) Query: 355 HPDRFIECYIAEQNMVSIAVGCATRNRTVPFCS--TFAAFFTRAFDQ----IRMAAISES 408 R I+ ++E G RT F S +F Q IR AA + Sbjct: 475 PEGRIIDSQLSEHQAEGWLEGYTLTGRTGAFASYESFLRVVDSMLTQHFKWIRQAADQKW 534 Query: 409 NINL-CGSHCGVSIGE----DGPSQMALEDLAMF--RSVPTSTVFYPSDGVATEKAVELA 461 + + S +G + L + + P+DG + A Sbjct: 535 RHDYPSLNVISTSTVFQQDHNGYTHQDPGMLTHLAEKKSDFIRQYLPADGNTLLAVFDRA 594 Query: 462 ANTK----GICFIRTSRPENAIIYNNNEDFQVGQAKV-----VLKSKDDQVTVIGAGVTL 512 + I + R + + G A + + + AG Sbjct: 595 FQDRSKINHIVASKQPRQQWFTKEEAEKLATDGIATIDWASTAKDGEAVDLVFASAGAEP 654 Query: 513 HEALAAAELLKKE 525 AA L E Sbjct: 655 TIETLAALHLVNE 667 >1PYP-A nrPDB Length = 285 Score = 31.3 bits (69), Expect = 1.2, Method: Composition-based stats. Identities = 28/138 (20%), Positives = 56/138 (40%), Gaps = 10/138 (7%) Query: 211 WHAIIVDGHS--VEELCKAFGQAKHQPTAIIAKT--FKGRGITG--VEDKESWHGKPLPK 264 W I +D + +L K+ P + A F+ I E++ ++ G+ K Sbjct: 152 WKVIAIDINDPLAPKLNDIEDVEKYFPGLLRATDEWFRIYKIPDGKPENQFAFSGEAKNK 211 Query: 265 NMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIATRKAYGQA 324 A II+E ++ + ++ D+ +D+ N+ +P P+Y A A +A Sbjct: 212 KYALDIIKETHNSWKQLIAGKSS----DSKGIDLTNVTLPDTPTYSKAASDAIPPASPKA 267 Query: 325 LAKLGHASDRIIALDGDT 342 A + + D+ + G Sbjct: 268 DAPIDKSIDKWFFISGSV 285 >1J3Q-A nrPDB Length = 190 Score = 31.3 bits (69), Expect = 1.5, Method: Composition-based stats. Identities = 20/107 (18%), Positives = 39/107 (36%), Gaps = 5/107 (4%) Query: 211 WHAIIVDGHSVEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQI 270 W ++ +G V A Q + + A T G E + K ++ Sbjct: 41 WKKMVEEGDPVVYEVYAIEQEEKEGDLNFATTVL---YPGKVGNEFFMTK--GHYHSKID 95 Query: 271 IQEIYSQIQSKKKILATPPQEDAPSVDIANIRMPSLPSYKVGDKIAT 317 E+Y ++ K +L P+ +A +++ + +P Y I T Sbjct: 96 RAEVYFALKGKGGMLLQTPEGEARFIEMEPGTIVYVPPYWAHRTINT 142 >3O0O-A nrPDB Length = 644 Score = 30.9 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 19/107 (17%), Positives = 33/107 (30%), Gaps = 10/107 (9%) Query: 12 LQALKDTAN-RLRIS---------SIQATTAAGSGHPTSCCSAAEIMAVLFFHTMRYKSQ 61 L+AL++ +R I T A +L+ + Y SQ Sbjct: 351 LEALQELVQIAVRFLDNVIDVNVFPIDKITKAVKESRRLGLGIMGFADLLYKLEIPYNSQ 410 Query: 62 DPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLNLRKISSDLD 108 + R+ + HA Y + E G E+ R + + Sbjct: 411 EARDFAANLMAFIALHAHRTSYELGKEKGNFPLLEISRYRTEDNFVP 457 >2QNE-A nrPDB Length = 495 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 11/64 (17%), Positives = 19/64 (29%), Gaps = 4/64 (6%) Query: 40 SCCSAAEIMAVLFFHTMRYKSQDPRNPHNDRFVLSKGHAAPILYAVWAEAGFLAEAELLN 99 S +A L ++ D V G+ AP +Y + + N Sbjct: 80 SKLKSAPAEFTLHAR----NPENNVVIGGDNIVFMPGYGAPFIYELDGSRRKTTLQDYEN 135 Query: 100 LRKI 103 K+ Sbjct: 136 FAKL 139 >4ZP1-A nrPDB Length = 568 Score = 30.5 bits (67), Expect = 2.3, Method: Composition-based stats. Identities = 27/150 (18%), Positives = 46/150 (30%), Gaps = 23/150 (15%) Query: 111 PVPKQAFTDVATGSLGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGSVWEAMAFA 170 P + ++ G +G + AA G A R ++GDG + +A Sbjct: 401 PNGARVEYEMQWGHIGWSVPAAFGYAVGAP-----ERRNILMVGDGSFQ--LTAQEVAQM 453 Query: 171 SIYKLDNLVAILDINRLGQS---DPAPLQHQMD-IYQKRCEAFGWH----------AIIV 216 KL ++ +++ + P + + Y E F + Sbjct: 454 VRLKLPVIIFLINNYGYTIAVMIHDGPYNNIKNWDYAGLMEVFNGNGGYDSGAGKGLKAK 513 Query: 217 DGHSVEELCKAFGQAKHQPTAIIAKTFKGR 246 G + E K PT I F GR Sbjct: 514 TGGELAEAIKVALANTDGPTLIEC--FIGR 541 >4MX8-A nrPDB Length = 315 Score = 29.4 bits (64), Expect = 5.4, Method: Composition-based stats. Identities = 29/187 (15%), Positives = 56/187 (29%), Gaps = 22/187 (11%) Query: 111 PVPKQAFTDVATGS--------LGQGLGAACGMAYTGKYFDKASYRVYCLLGDGELSEGS 162 PV ++ +V A G G D + L D + G+ Sbjct: 33 PVYEETTVEVPVDPQRIVVFDMAALDTIGALGGEIAGAPLDSVPDYLEEYLADDAFNAGT 92 Query: 163 VWEAMAFASIYKLDNLVAI--------LDINRLGQSDPAPLQHQMDIYQKRCEAFGWHAI 214 ++EA A + +L+ + D+N + + L+ ++ F + Sbjct: 93 LFEADLIAIEAQQPDLIVVGGRSSGLWADLNEIAPTIDLSLRGSYLDTLEQNTTFLGKVL 152 Query: 215 IVDGHS---VEELCKAFGQAKHQPTAIIAKTFKGRGITGVEDKESWHGKPLPKNMAEQII 271 + + + EL +AK A+ + G GI + S + Sbjct: 153 GAEAEAESVLAELEAGIAEAK---AAVTEASGTGLGIMVSGGQLSALSPNTGNDPRGARG 209 Query: 272 QEIYSQI 278 IY Sbjct: 210 GLIYDVF 216 >4RNL-A nrPDB Length = 343 Score = 28.6 bits (62), Expect = 7.6, Method: Composition-based stats. Identities = 14/82 (17%), Positives = 24/82 (29%), Gaps = 1/82 (1%) Query: 245 GRGITGVEDKESWHGKPLPKNMAEQIIQEIYSQIQSKKKILATPPQEDAPSVDIANIRMP 304 G GI G A + Y + + P+ A D + R Sbjct: 212 GTGIPVPGAPAEVTGTRFDFRAARAVAG-AYDHNFALDGGVREAPRTVAELYDPRSGRAL 270 Query: 305 SLPSYKVGDKIATRKAYGQALA 326 +L + + G ++ T L Sbjct: 271 ALATTEPGLQLYTADHLDGTLT 292 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.123 0.293 Lambda K H 0.267 0.0374 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 18,944,358 Number of Sequences: 36641 Number of extensions: 682992 Number of successful extensions: 2180 Number of sequences better than 10.0: 34 Number of HSP's better than 10.0 without gapping: 34 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 1999 Number of HSP's gapped (non-prelim): 68 length of query: 623 length of database: 10,336,785 effective HSP length: 103 effective length of query: 520 effective length of database: 6,562,762 effective search space: 3412636240 effective search space used: 3412636240 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 62 (28.6 bits)