BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P29218 (277 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1IMD-A nrPDB 575 e-165 2BJI-A nrPDB 523 e-149 4AS5-A nrPDB 510 e-145 2CZH-A nrPDB 340 4e-94 6IB8-A nrPDB 153 9e-38 5ZHH-A nrPDB 148 3e-36 3LV0-A nrPDB 134 5e-32 2P3V-A nrPDB 129 2e-30 5J16-A nrPDB 127 5e-30 2PCR-A nrPDB 116 1e-26 2Q74-A nrPDB 108 2e-24 1G0H-A nrPDB 87 1e-17 5EQA-A nrPDB 76 2e-14 1VDW-A nrPDB 76 2e-14 3QMF-A nrPDB 75 3e-14 5YHT-A nrPDB 72 4e-13 1LBZ-A nrPDB 70 1e-12 1XI6-A nrPDB 69 2e-12 4O7I-A nrPDB 63 1e-10 1JP4-A nrPDB 60 1e-09 3B8B-A nrPDB 58 4e-09 4N81-A nrPDB 55 2e-08 4QXD-A nrPDB 51 5e-07 5ESY-A nrPDB 50 8e-07 1KA0-A nrPDB 48 4e-06 2WEF-A nrPDB 48 6e-06 5DJK-A nrPDB 39 0.004 2PW6-A nrPDB 30 1.4 3GEH-A nrPDB 30 1.7 4XF7-A nrPDB 28 3.0 1WDZ-A nrPDB 28 3.7 5O6V-A nrPDB 28 5.1 3RMJ-A nrPDB 28 5.9 2NQL-A nrPDB 28 6.4 4BY7-X nrPDB 27 6.9 4BXZ-X nrPDB 27 8.4 >1IMD-A nrPDB Length = 277 Score = 575 bits (1482), Expect = e-165, Method: Compositional matrix adjust. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE Sbjct: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 Query: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG Sbjct: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME Sbjct: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 Query: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG Sbjct: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 Query: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED 277 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED Sbjct: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED 277 >2BJI-A nrPDB Length = 277 Score = 523 bits (1348), Expect = e-149, Method: Compositional matrix adjust. Identities = 245/277 (88%), Positives = 264/277 (95%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 MADPWQECMDYAVTLA QAGEVV EA+KNEMN+M+KSSP DLVTATDQKVEKMLI+SIKE Sbjct: 1 MADPWQECMDYAVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKE 60 Query: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVH FPFVAVSIGF VNKK+EFG Sbjct: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFG 120 Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 +VYSC+E KMYT RKGKGAFCNGQKLQVS QEDITKSLLVTELGSSRTPETVR++LSN+E Sbjct: 121 IVYSCLEDKMYTGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIE 180 Query: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 +L C+P+HGIR VGTAA+NMCLVA G ADAYYEMGIHCWDVAGAGIIVTEAGGVL+DVTG Sbjct: 181 RLLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTG 240 Query: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED 277 GPFDLMSRRVIA++N+ LAERIAKEIQ+IPLQRDDED Sbjct: 241 GPFDLMSRRVIASSNKTLAERIAKEIQIIPLQRDDED 277 >4AS5-A nrPDB Length = 277 Score = 510 bits (1313), Expect = e-145, Method: Compositional matrix adjust. Identities = 239/276 (86%), Positives = 261/276 (94%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 MADPWQECMDYAV LARQAGE++ EA+KNEM+VM+KSSP DLVT TDQKVEKML+SSIKE Sbjct: 1 MADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKE 60 Query: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 KYP HSFIGEESVAAGEK++ T+ PTW+IDPIDGTTNFVHRFPFVAVSIGF VNK++EFG Sbjct: 61 KYPCHSFIGEESVAAGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFG 120 Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 +VYSCVE KMYT RKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSR PET+R+VLSNME Sbjct: 121 IVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNME 180 Query: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 KL IP+HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWD+AGAGIIVTEAGGVLMDVTG Sbjct: 181 KLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTG 240 Query: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 GPFDLMSRR+IAAN+ LA+RIAKEI++IPLQRDDE Sbjct: 241 GPFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDE 276 >2CZH-A nrPDB Length = 299 Score = 340 bits (872), Expect = 4e-94, Method: Compositional matrix adjust. Identities = 147/275 (53%), Positives = 209/275 (76%) Query: 2 ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61 A PW+EC AV LA +AG+++ +A+ E V K+S DLVT TD VE ++IS ++E+ Sbjct: 24 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 83 Query: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121 +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV Sbjct: 84 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 143 Query: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181 +Y C E ++YT R+G+GAFCNGQ+L+VS + D++K+L++TE+G R P T+++ LSNME+ Sbjct: 144 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 203 Query: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 L HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 204 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 263 Query: 242 PFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 P DLM+ RV+AA+ R +A IA+ +Q I RDDE Sbjct: 264 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 298 >6IB8-A nrPDB Length = 271 Score = 153 bits (386), Expect = 9e-38, Method: Compositional matrix adjust. Identities = 84/257 (32%), Positives = 141/257 (54%), Gaps = 6/257 (2%) Query: 9 MDYAVTLARQAGEVVCEAIKNEMNV-MLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSF 67 ++ AV AR+AG ++ + + V + D VT D+ E ++I +I++ YP H+ Sbjct: 9 LNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTI 68 Query: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 127 I EES GE + W+IDP+DGTTNF+ R P AVSI + + E VVY + Sbjct: 69 ITEES---GELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMR 125 Query: 128 GKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPV 187 +++TA +G+GA NG +L+ S D+ ++L T + + ++ + KLF Sbjct: 126 NELFTATRGQGAQLNGYRLRGSTARDLDGTILATGF-PFKAKQYATTYINIVGKLFN-EC 183 Query: 188 HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMS 247 R G+AA+++ VA G D ++E+G+ WD A ++V EAGG++ D TGG +++ Sbjct: 184 ADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLT 243 Query: 248 RRVIAANNRILAERIAK 264 ++A N R++ +A Sbjct: 244 GNIVAGNPRVVKAMLAN 260 >5ZHH-A nrPDB Length = 270 Score = 148 bits (373), Expect = 3e-36, Method: Compositional matrix adjust. Identities = 88/248 (35%), Positives = 127/248 (51%), Gaps = 13/248 (5%) Query: 28 KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNP-T 86 K E + K P DLVTA D+ E +++ I+ +P HS + EES G + DN Sbjct: 28 KLEDAITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGNQ----DNEYL 83 Query: 87 WIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKL 146 W IDP+DGTTN+ H++P VSIG +N + GV+Y +++ G GA N + + Sbjct: 84 WAIDPLDGTTNYAHQYPAFCVSIGLLINGVPQVGVIYDPFHDELFRGAAGLGATRNRRPI 143 Query: 147 QVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVH---GIRSVGTAAVNMCLV 203 +VS +++KSLLVT R R N FC H G+R G+AA+++ V Sbjct: 144 KVSDTSELSKSLLVTGFAYDR-----RETPDNNYAEFCHLTHLTQGVRRSGSAALDLAHV 198 Query: 204 ATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIA 263 A G D Y+E GI WDV I++ EAGG + P + + R++A N I Sbjct: 199 ACGRVDGYWERGISPWDVVAGVILLEEAGGKVTAYDSTPLKIATGRILATNGSIHDNLSR 258 Query: 264 KEIQVIPL 271 +QV PL Sbjct: 259 ALMQVPPL 266 >3LV0-A nrPDB Length = 267 Score = 134 bits (336), Expect = 5e-32, Method: Compositional matrix adjust. Identities = 92/265 (34%), Positives = 138/265 (52%), Gaps = 20/265 (7%) Query: 6 QECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSH 65 Q M +L R GEV + V LK P D V+ D+K EK++ + + + P Sbjct: 16 QAAMKAGRSLVRDYGEV------QNLQVSLKG-PADYVSQADRKAEKIIFNELSKARPKF 68 Query: 66 SFIGEESVAAGEKSILTDNP-TWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYS 124 F+ EES E+ I D+ +I+DP+DGTTNF+H PF AVSI KI GV+Y+ Sbjct: 69 GFLMEES----EEIIGEDSQHRFIVDPLDGTTNFLHGIPFFAVSIALESQGKIVAGVIYN 124 Query: 125 CVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTP--ETVRMVLSNMEKL 182 + +++TA +G GAF N ++ +VS + + ++ T + P T + L N+ Sbjct: 125 PINDELFTAERGSGAFFNDRRCRVSARRRLEDCVIATGMPHLGRPGHGTYLIELRNV--- 181 Query: 183 FCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGP 242 V GIR GTAA+++ VA G D ++E + WD+A ++V EAGG + D GG Sbjct: 182 -MAEVSGIRRFGTAALDLAYVAAGRTDGFWEDNLQIWDMAAGILMVREAGGFVTDKEGGN 240 Query: 243 FDLMSRRVIAANN--RILAERIAKE 265 + +IA N RI ER K+ Sbjct: 241 DIFRKKNIIAGNEHIRIKLERALKK 265 >2P3V-A nrPDB Length = 256 Score = 129 bits (323), Expect = 2e-30, Method: Compositional matrix adjust. Identities = 78/249 (31%), Positives = 133/249 (53%), Gaps = 14/249 (5%) Query: 9 MDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFI 68 +D+++ L R+ G ++ NV K+ D+VT D++ ++M++ I++ +P + + Sbjct: 4 LDFSIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDENIM 63 Query: 69 GEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEG 128 EE + EK + WIIDPIDGT NFVH P ++S+ + N +++ GVV++ Sbjct: 64 AEEGIF--EKG----DRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPALN 117 Query: 129 KMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVH 188 + A +G GAF NG++++VS+ + + + T S T + + MEK Sbjct: 118 ETLYAEEGSGAFFNGERIRVSENASLEECVGST---GSYVDFTGKFI-ERMEK----RTR 169 Query: 189 GIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSR 248 IR +G+AA+N V G D + I+ WD+A IIV EAGG++ D +G + S+ Sbjct: 170 RIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAFSK 229 Query: 249 RVIAANNRI 257 I +N I Sbjct: 230 NFIFSNGLI 238 >5J16-A nrPDB Length = 283 Score = 127 bits (319), Expect = 5e-30, Method: Compositional matrix adjust. Identities = 76/255 (29%), Positives = 125/255 (49%), Gaps = 7/255 (2%) Query: 11 YAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 +A L ++AG + + ++ + + KS+P DLVT D+ E + +I E YP+H +GE Sbjct: 14 FAQGLIQEAGIRIKQLMEQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPNHQVLGE 73 Query: 71 ESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKM 130 E G + W++DPIDGT NFVH+ A+SIG ++ K G VY + + Sbjct: 74 E--GHGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVL 131 Query: 131 YTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGI 190 Y A+ G+GA+ Q L+ ++ +S++ P +L + K Sbjct: 132 YHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKP-----ILGEIFKEIVNDSRSA 186 Query: 191 RSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRV 250 R+ G+AA+ + VATG +AY + WD AG +I+ E G ++ G P + Sbjct: 187 RAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNS 246 Query: 251 IAANNRILAERIAKE 265 I NR L + I+ + Sbjct: 247 ILVGNRGLHQEISND 261 >2PCR-A nrPDB Length = 264 Score = 116 bits (290), Expect = 1e-26, Method: Compositional matrix adjust. Identities = 82/260 (31%), Positives = 131/260 (50%), Gaps = 15/260 (5%) Query: 6 QECMDYAVTLARQAGEVVCE---AIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKY 62 ++ ++ A A G+V+ E +K E N+ K D V+ D+ E+ + I + + Sbjct: 5 KKYLEVAKIAALAGGQVLKENFGKVKKE-NIEEKGEK-DFVSYVDKTSEERIKEVILKFF 62 Query: 63 PSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVV 122 P H +GEE A G S W IDP+DGT N+++ FP AVS+G ++ G V Sbjct: 63 PDHEVVGEEMGAEGSGS----EYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAV 118 Query: 123 YSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKL 182 Y K+Y KG GA+ NG++++V E + + +V SR+ + + L+ + + Sbjct: 119 YLPYFDKLYWGAKGLGAYVNGKRIKVKDNESLKHAGVVYGF-PSRSRRDISIYLNIFKDV 177 Query: 183 FCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGP 242 F V +R G AAV++C+VA G D E + WD+ +I+ EAGGV + G P Sbjct: 178 FY-EVGSMRRPGAAAVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGVYT-LVGEP 235 Query: 243 FDLMSRRVIAANNRILAERI 262 F + I A N+ L + I Sbjct: 236 FGVSD---IIAGNKALHDFI 252 >2Q74-A nrPDB Length = 299 Score = 108 bits (271), Expect = 2e-24, Method: Compositional matrix adjust. Identities = 69/204 (33%), Positives = 105/204 (51%), Gaps = 10/204 (4%) Query: 23 VCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGE-KSIL 81 + A + V KSSP D VT D E++L + + P +GEE + + Sbjct: 36 ISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATP 95 Query: 82 TDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFC 141 +D TW++DPIDGT NFV+ P AVSIG V G V +Y+A G GA Sbjct: 96 SDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHL 155 Query: 142 NGQK----LQVSQQEDITKSLLVTELGSS-RTPETVRMVLSNMEKLFCIPVHGIRSVGTA 196 ++ L+ + ++++ +LL T G S R E +L+++ L V +R +G+A Sbjct: 156 TDERGRHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPL----VRDVRRIGSA 211 Query: 197 AVNMCLVATGGADAYYEMGIHCWD 220 A+++C+VA G DAYYE G+ WD Sbjct: 212 ALDLCMVAAGRLDAYYEHGVQVWD 235 >1G0H-A nrPDB Length = 252 Score = 86.7 bits (213), Expect = 1e-17, Method: Compositional matrix adjust. Identities = 59/194 (30%), Positives = 98/194 (50%), Gaps = 21/194 (10%) Query: 72 SVAAGEKSILTDNPTW--IIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGK 129 ++ + E ++ ++ W +IDPIDG+ NF++ PF A G N + +G+ Y + Sbjct: 61 NIVSEELGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEFLTKS 120 Query: 130 MYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHG 189 Y A KGKGA+ NG+K++V +D + +V S+ + +EKL V Sbjct: 121 FYEAYKGKGAYLNGRKIKV---KDFNPNNIVISYYPSKKID--------LEKLRN-KVKR 168 Query: 190 IRSVGTAAVNMCLVATGGADAYYEM--GIHCWDVAGAGIIVTEAGGVLMDVTGG--PFDL 245 +R G + MC VA G DA +++ + D+A + II EAG ++ D G FDL Sbjct: 169 VRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDELKFDL 228 Query: 246 MSR---RVIAANNR 256 + +I AN++ Sbjct: 229 NATDRLNIIVANSK 242 >5EQA-A nrPDB Length = 277 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 68/270 (25%), Positives = 121/270 (44%), Gaps = 24/270 (8%) Query: 10 DYAVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFI 68 D A A AG+V+ + KN +++ K+ + VT DQ E+ ++S I + +PSH+ Sbjct: 19 DVANKAANAAGDVIRKYFRKNNFDIIHKND-LSPVTIADQSAEEAMVSVILDNFPSHAVY 77 Query: 69 GEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEG 128 GEE ++ + + W++DPIDGT +F+ P I N G++ V Sbjct: 78 GEEKGWRCKQD--SADYVWVLDPIDGTKSFITGKPLFGTLIALLQNGTPILGIIDQPVLK 135 Query: 129 KMYTARKGKGAFCNGQKLQVSQQEDITKSLLVT---ELGSSRTPETVRMVLSNMEKLFCI 185 + + GK NGQ++ D++++ L T L S E V ++ I Sbjct: 136 ERWIGITGKRTTLNGQEVSTRTCADLSQAYLYTTSPHLFSGDAEEAFIRVRDKVK----I 191 Query: 186 PVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG----- 240 P++G A L+++G D E G+ +D ++ +GGV+ D G Sbjct: 192 PLYGCDCYAYA-----LLSSGFVDLVVESGLKPYDFLALIPVIEGSGGVITDWKGHQLRW 246 Query: 241 --GPFDL-MSRRVIAANNRILAERIAKEIQ 267 P + S V+AA ++ + ++ +Q Sbjct: 247 EASPLSIATSFNVVAAGDKQIHQQALDSLQ 276 >1VDW-A nrPDB Length = 254 Score = 75.9 bits (185), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 48/189 (25%), Positives = 90/189 (47%), Gaps = 22/189 (11%) Query: 86 TWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQK 145 T ++DP+DG+ NF++ PF AVS+ K + +Y + ++Y GKG++ NG+K Sbjct: 80 TVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPIVERLYEGIPGKGSYLNGEK 139 Query: 146 LQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVAT 205 ++V + + T+ ++ + V+ R++G A+ + +A Sbjct: 140 IKVRELAEKPSISFYTKGKGTKIIDKVKRT---------------RTLGAIALELAYLAR 184 Query: 206 GGADAYYEMG--IHCWDVAGAGIIVTEAGGVLMDVTGGPFDLM-----SRRVIAANNRIL 258 G DA ++ + D+A +I EAG ++ D+ G ++ +IAANN L Sbjct: 185 GALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDGKDVEITFSATEKVNIIAANNEEL 244 Query: 259 AERIAKEIQ 267 E I + I+ Sbjct: 245 LETILRSIE 253 >3QMF-A nrPDB Length = 273 Score = 75.1 bits (183), Expect = 3e-14, Method: Compositional matrix adjust. Identities = 61/247 (24%), Positives = 102/247 (41%), Gaps = 33/247 (13%) Query: 17 RQAGEVVCEAIKN----------EMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHS 66 +Q +++C +K EM K DLVT D+++++ + +P H Sbjct: 15 QQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQ 74 Query: 67 FIGEESVAAGEKSILTD--NPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYS 124 + EE A ++T+ N WI+DPIDGT N V + + + + K VY Sbjct: 75 LLAEEKSNA----MITNEINHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYD 130 Query: 125 CVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFC 184 K+Y A +G+GAFCNG K++ + +++ + M L ++ LF Sbjct: 131 YPHKKLYKAIRGEGAFCNGIKMEEPPSLKLEDAII--------SFNAQVMNLDTVQDLFD 182 Query: 185 IPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGI--------IVTEAGGVLM 236 R VG ++ VA G A+ WD+A + + T G + Sbjct: 183 ASF-SYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAID 241 Query: 237 DVTGGPF 243 + G PF Sbjct: 242 HLKGAPF 248 >5YHT-A nrPDB Length = 267 Score = 71.6 bits (174), Expect = 4e-13, Method: Compositional matrix adjust. Identities = 68/242 (28%), Positives = 106/242 (43%), Gaps = 24/242 (9%) Query: 12 AVTLARQAGEVVCEAIKNEMNVMLKSSPVDL--VTATDQKVEKMLISSIKEKYPSHSFIG 69 A+ LA +A E+ +++ + + P DL VT D+ VE + ++ P +G Sbjct: 16 ALALADRADEL-TRVRFGALDLRIDTKP-DLTPVTDADRAVESDVRQTLGRDRPGDGVLG 73 Query: 70 EESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGK 129 EE G + T WI+DPIDGT NFV P A I + GVV + + Sbjct: 74 EEF---GGSTTFTGR-QWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAPALQR 129 Query: 130 MYTARKGKGAFCN-----GQKLQVSQ--QEDITKSLLVTELGSSRTPETVRMVLSNMEKL 182 + A +G+GAF + +L VS + + G +R P + + + Sbjct: 130 RWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWAR-PGLRERFIGLTDTV 188 Query: 183 FCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVL--MDVTG 240 + + +G ++ CLVA G D E + WD+A I+V EAGG L +D Sbjct: 189 WRVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLDGVA 242 Query: 241 GP 242 GP Sbjct: 243 GP 244 >1LBZ-A nrPDB Length = 252 Score = 69.7 bits (169), Expect = 1e-12, Method: Compositional matrix adjust. Identities = 51/200 (25%), Positives = 93/200 (46%), Gaps = 33/200 (16%) Query: 72 SVAAGEKSILTDNPTWI-IDPIDGTTNFVHRFPFVAVSIGFAVNKKIE---FGVVYSCVE 127 +V E +L + ++ +DP+DGT N P +VS+ F+ + K++ FG VY+ Sbjct: 63 TVVTEESGVLGEGDVFVALDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVYNLAT 122 Query: 128 GKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPV 187 G Y A GA+ NG++++VS E++ + ++ P+ P Sbjct: 123 GDEYYA-DSSGAYRNGERIEVSDAEELYCNAIIY------YPDRK------------FPF 163 Query: 188 HGIRSVGTAAVNMCLVATGGADAYYEMG----IHCWDVAGAGIIVTEAGGVLMDVTG--- 240 +R G+AA +C A G D + ++ + +D A I +AGG + ++ G Sbjct: 164 KRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELDGESL 223 Query: 241 --GPFDLMSR-RVIAANNRI 257 FD+ R ++AAN ++ Sbjct: 224 GNKKFDMQERLNIVAANEKL 243 >1XI6-A nrPDB Length = 262 Score = 69.3 bits (168), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 57/218 (26%), Positives = 99/218 (45%), Gaps = 29/218 (13%) Query: 34 MLKSSPV-DLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNP---TWII 89 ++K SP D D+ E +++S I E +G V+ E+ + DN T I+ Sbjct: 41 LVKISPSGDETKLVDKLAEDLILSRITE-------LGVNVVS--EEVGVIDNESEYTVIV 91 Query: 90 DPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVS 149 DP+DG+ NF+ PF A+S+ K + ++Y + + + G+GAF NG++++V Sbjct: 92 DPLDGSYNFIAGIPFFALSLAVFKKDKPIYAIIYEPMTERFFEGIPGEGAFLNGKRIKVR 151 Query: 150 QQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGAD 209 + D S+ G E V+ V R++G A+ + +A G D Sbjct: 152 KTPDEKPSISFYSRGKGH--EIVKHVKRT------------RTLGAIALELAYLAMGALD 197 Query: 210 AYYEMG--IHCWDVAGAGIIVTEAGGVLMDVTGGPFDL 245 ++ + D+A II EAG ++ D G D+ Sbjct: 198 GVVDVRKYVRPTDIAAGTIIAKEAGALIKDSAGKDIDI 235 >4O7I-A nrPDB Length = 325 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 73/304 (24%), Positives = 116/304 (38%), Gaps = 63/304 (20%) Query: 9 MDYAVTLARQAGEVVCE--------AIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 D + LA + +V C+ + ++ + SPV T D V+ + I E Sbjct: 3 FDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSPV---TVGDYSVQAYVNKKIHE 59 Query: 61 KYPSHSFIGEESVAAG-----------------------EKSILTDNPT------WIIDP 91 +P + EE KSI N T W++DP Sbjct: 60 TFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDP 119 Query: 92 IDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE---GKMYTARKGKGA-------FC 141 IDGT F+ R + AV + F ++ I+ GV+ C G + A+KG GA Sbjct: 120 IDGTLGFLRREQY-AVCLAFMIDGDIKVGVL-GCPNFEGGLIVAAQKGCGAKMFSVNDIK 177 Query: 142 NGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMC 201 NG+ + VS + + S T ++ ++ ++ PV A+ Sbjct: 178 NGKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQCKYMAI--- 234 Query: 202 LVATGGADAYYEMGIHC------WDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANN 255 A+G AD Y + + WD A +IV EAGG + D+ G D R + N+ Sbjct: 235 --ASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNH 292 Query: 256 RILA 259 I+A Sbjct: 293 GIVA 296 >1JP4-A nrPDB Length = 308 Score = 59.7 bits (143), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 75/308 (24%), Positives = 121/308 (39%), Gaps = 71/308 (23%) Query: 12 AVTLARQAGEVV-CEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 A ++A++AG +V C + ++ ++ K+S DL T D+ V+ + SS+ K+P + IGE Sbjct: 15 AYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLSRKFPKLTIIGE 74 Query: 71 ESVAAGE--KSILTDNPT----------------------WIIDPIDGTTNFVH-RFPFV 105 E + GE + ++ D + W +DP+DGT + V Sbjct: 75 EDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVW-VDPVDGTKEYTEGLLDNV 133 Query: 106 AVSIGFAVNKKIEFGVVYS----------CVEGKMYTARKGKGAFCNGQKLQVSQQEDIT 155 V IG A K G++ V G+ G GAF K + + IT Sbjct: 134 TVLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGFQLKEAPAGKHIIT 193 Query: 156 KSL-----LVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADA 210 + LVT+ ++ P+ V VG A + + G A A Sbjct: 194 TTRSHSNKLVTDCIAAMNPDNV------------------LRVGGAGNKIIQLIEGKASA 235 Query: 211 YYEMGIHC--WDVAGAGIIVTEAGGVLMDVTGGPFD-------LMSRRVIAA--NNRILA 259 Y C WD +I+ GG L D+ G P + S V+AA N A Sbjct: 236 YVFASPGCKKWDTCAPEVILHAVGGKLTDIHGNPLQYDKEVKHMNSAGVLAALRNYEYYA 295 Query: 260 ERIAKEIQ 267 R+ + ++ Sbjct: 296 SRVPESVK 303 >3B8B-A nrPDB Length = 292 Score = 58.2 bits (139), Expect = 4e-09, Method: Compositional matrix adjust. Identities = 64/223 (28%), Positives = 105/223 (47%), Gaps = 34/223 (15%) Query: 12 AVTLARQAGEVVC---EAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE-KYPSHSF 67 A+ A +AGE + E K++ + K+ L A D+K + +++ + E +P S Sbjct: 27 AIDAALKAGEKILSIYEDPKSDFEIERKADNSPLTIA-DRKAHEAIVAILNETPFPVLSE 85 Query: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 127 G+ A + T WI+DP+DGT F+ R V+I N GV+Y V+ Sbjct: 86 EGKHMDYAVRRGWDT---LWIVDPLDGTKEFIKRNGEFTVNIALVQNAVPVMGVIYVPVK 142 Query: 128 GKMYTARKGKGAF-CNG----QKLQVSQQEDITKS-----------LLVTELGSSRTPET 171 ++Y A +G GA+ C+G + V+ Q+ I KS + S TPET Sbjct: 143 KELYFAVEGTGAYKCSGIVGLEDEGVTLQQMIEKSERMPLADARDHFIAVASRSHLTPET 202 Query: 172 VRMVLSNMEKLFCIPVHG---IRSVGTAAVNMCLVATGGADAY 211 +++++K HG + S G+ ++ +CLVA G AD Y Sbjct: 203 -ETYIADLKK-----KHGNVELISSGS-SIKICLVAEGKADVY 238 >4N81-A nrPDB Length = 259 Score = 55.5 bits (132), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 62/260 (23%), Positives = 108/260 (41%), Gaps = 18/260 (6%) Query: 5 WQECMDYAVTLARQAGEVVCEAIKNEMNVMLKS--SPVDLVTATDQKVEKMLISSIKEKY 62 +++ + A LA A +++ + + + LK+ SPV T D+ E+ + + ++++ Sbjct: 6 YEDDIRLAHRLADVAADIIRPFFRAPLTIDLKADHSPV---TKADRGAEQAMRAILEQER 62 Query: 63 PSHSFIGEE-SVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121 P GEE V+ + L W++DPIDGT F+ I + + G+ Sbjct: 63 PEDGIFGEEMGVSRPDARRL-----WVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGI 117 Query: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181 + + + + K NG+ + + +LL T S E V + + Sbjct: 118 INQPIHQERWVGVKDLPTSFNGEVIHTRSCPALDHALLATT--SPWLFEKEGEVHFDKIR 175 Query: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 L C +G N L++ G D E G+ +D A IV AGG++ D Sbjct: 176 LKCRDT----LLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIMRDWQNR 231 Query: 242 PFDLMS-RRVIAANNRILAE 260 P + S VIAA + L E Sbjct: 232 PLNKNSVGEVIAAGDHHLIE 251 >4QXD-A nrPDB Length = 293 Score = 51.2 bits (121), Expect = 5e-07, Method: Compositional matrix adjust. Identities = 63/256 (24%), Positives = 105/256 (41%), Gaps = 47/256 (18%) Query: 13 VTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEES 72 +T ++A + + K E+ + KS + VT D + ++++ S IK KYP+ + IGEE Sbjct: 13 ITAVKEASYSISK-FKEEVEIKYKSDGSE-VTQVDTQSQQIIFSIIKNKYPTINIIGEED 70 Query: 73 VAAGEKSILTDN--PT--------------------WIIDPIDGTTNFVHR-FPFVAVSI 109 V G + DN PT +DP+DGT + H+ + V V + Sbjct: 71 VENG----IPDNQLPTITQLSFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCVLV 126 Query: 110 GFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTP 169 G K G+V K + + A N +S Q K + V Sbjct: 127 GVTYKGKPMIGIV-----SKPFYNNEITFAIENYIS-SISLQPLNDKIIFVC-------- 172 Query: 170 ETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIH--CWDVAGAGII 227 + + + ++ K F P + ++ G + M + AD YY I WD A +I Sbjct: 173 -SKKNDIQHLIKSFPDP-YEVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQVI 230 Query: 228 VTEAGGVLMDVTGGPF 243 + GG++ D+ G P Sbjct: 231 LEAQGGIVCDIYGNPL 246 >5ESY-A nrPDB Length = 346 Score = 50.4 bits (119), Expect = 8e-07, Method: Compositional matrix adjust. Identities = 51/212 (24%), Positives = 84/212 (39%), Gaps = 49/212 (23%) Query: 87 WIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE------------------- 127 W++DPIDGT F+ R AV++G K+ GV+ +C Sbjct: 131 WVLDPIDGTKGFL-RGDQYAVALGLLEEGKVVLGVL-ACPNLPLASIAGNNKNKSSSDEI 188 Query: 128 GKMYTARKGKGAF-------CNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 G ++ A G G + + K+QVS E+ ++ + + + ++N Sbjct: 189 GCLFFATIGSGTYMQLLDSKSSPVKVQVSSVENPEEASFFESFEGAHSLHDLSSSIANKL 248 Query: 181 KLFCIPV-------HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGG 233 + PV +G S G A+ + G Y E WD I+VTEAGG Sbjct: 249 GVKAPPVRIDSQAKYGALSRGDGAIYLRFPHKG----YRE---KIWDHVAGAIVVTEAGG 301 Query: 234 VLMDVTGGPFDL-------MSRRVIAANNRIL 258 ++ D G P D + +I AN +++ Sbjct: 302 IVTDAAGKPLDFSKGKYLDLDTGIIVANEKLM 333 >1KA0-A nrPDB Length = 357 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 53/200 (26%), Positives = 79/200 (39%), Gaps = 45/200 (22%) Query: 87 WIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVV---------YSCVE-------GKM 130 W +DPIDGT F+ F AV + V+ ++ G + Y + G + Sbjct: 139 WCLDPIDGTKGFLRGEQF-AVCLALIVDGVVQLGCIGCPNLVLSSYGAQDLKGHESFGYI 197 Query: 131 YTARKGKGAFCNGQ-------KLQVSQQEDITKSLLVTEL----GSSRTPETVRMVLSNM 179 + A +G GAF + K+ V +D TK ++ E SS +T N+ Sbjct: 198 FRAVRGLGAFYSPSSDAESWTKIHVRHLKD-TKDMITLEGVEKGHSSHDEQTAIKNKLNI 256 Query: 180 EKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHC------WDVAGAGIIVTEAGG 233 K + + CL+A G AD Y + I WD A +IV EAGG Sbjct: 257 SKSLHLD---------SQAKYCLLALGLADVYLRLPIKLSYQEKIWDHAAGNVIVHEAGG 307 Query: 234 VLMDVTGG-PFDLMSRRVIA 252 + D P D + R +A Sbjct: 308 IHTDAMEDVPLDFGNGRTLA 327 >2WEF-A nrPDB Length = 311 Score = 47.8 bits (112), Expect = 6e-06, Method: Compositional matrix adjust. Identities = 65/271 (23%), Positives = 103/271 (38%), Gaps = 60/271 (22%) Query: 12 AVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 A ++A++AG +V I + ++ ++ K+ DL T D+ + + SS+ K+P + IGE Sbjct: 11 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 70 Query: 71 ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVH-RFPFVA 106 E + + E L ++ W +DP+DGT + V Sbjct: 71 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 130 Query: 107 VSIGFAVNKKIEFGVVYS----------CVEGKMYTARKGKGAFCNGQKLQVSQQEDITK 156 V IG A K GV+ V G+ G GAF K + + IT Sbjct: 131 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 190 Query: 157 SL-----LVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAY 211 + LVT+ ++ P+ V VG A + + G A AY Sbjct: 191 TRSHSNKLVTDCVAAMNPDAV------------------LRVGGAGNKIIQLIEGKASAY 232 Query: 212 YEMGIHC--WDVAGAGIIVTEAGGVLMDVTG 240 C WD +I+ GG L D+ G Sbjct: 233 VFASPGCKKWDTCAPEVILHAVGGKLTDIHG 263 >5DJK-A nrPDB Length = 288 Score = 38.5 bits (88), Expect = 0.004, Method: Compositional matrix adjust. Identities = 19/60 (31%), Positives = 32/60 (53%), Gaps = 2/60 (3%) Query: 39 PVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNF 98 P L A D++ +L+ ++ + P + + EE A + + L + WIIDP+DGT F Sbjct: 63 PWTLGEAGDRQANSLLLRRLQAERPGDAVLSEE--AHDDLARLKSDRVWIIDPLDGTREF 120 >2PW6-A nrPDB Length = 271 Score = 29.6 bits (65), Expect = 1.4, Method: Compositional matrix adjust. Identities = 16/58 (27%), Positives = 24/58 (41%) Query: 219 WDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 W G G+ E + D G P L A + LA+R+ + + IP+ D E Sbjct: 58 WFTRGTGVTAMETPPTIHDFGGFPQALYDTHYPAPGSPALAQRLVELLAPIPVTLDKE 115 >3GEH-A nrPDB Length = 462 Score = 29.6 bits (65), Expect = 1.7, Method: Compositional matrix adjust. Identities = 17/75 (22%), Positives = 37/75 (49%), Gaps = 10/75 (13%) Query: 121 VVYSCVEGKMYTARKGK---GAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLS 177 V+ C+E A+ G+ AF NG+ D+T++ + +L +R+P+ + L+ Sbjct: 103 VLQLCLESGARLAQPGEFTLRAFLNGRL-------DLTQAESIADLVGARSPQAAQTALA 155 Query: 178 NMEKLFCIPVHGIRS 192 ++ P+ +R+ Sbjct: 156 GLQGKLAHPIRQLRA 170 >4XF7-A nrPDB Length = 273 Score = 28.5 bits (62), Expect = 3.0, Method: Compositional matrix adjust. Identities = 34/119 (28%), Positives = 45/119 (37%), Gaps = 8/119 (6%) Query: 71 ESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKM 130 E + GE +L NP P T+ + +FPFVAV I + + Y ++G Sbjct: 97 EELPDGEYDVLLMNPVAREVPPALVTSALKKFPFVAVDIQGFIRSSSPGEIQYQPIDGSF 156 Query: 131 YTARKGKGA-FCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVH 188 K A Q LQ E + LL S PE + L E F PVH Sbjct: 157 LKGVKILHADLGEYQYLQGFSPEFVDVLLL------SNGPEPGKAFLHGREYTFE-PVH 208 >1WDZ-A nrPDB Length = 242 Score = 28.5 bits (62), Expect = 3.7, Method: Compositional matrix adjust. Identities = 40/148 (27%), Positives = 59/148 (39%), Gaps = 20/148 (13%) Query: 23 VCEAIKNEMNVMLKSSPVDLVTATDQKVE---KMLISSIKEKYPSHSFIGE-------ES 72 V I+N++ MLKS +L+T +QKVE + L +++K+ G+ E Sbjct: 85 VHRQIQNQLEEMLKSFHNELLTQLEQKVELDSRYLSAALKKYQTEQRSKGDALDKCQAEL 144 Query: 73 VAAGEKSILTDNPTWIIDP----IDGTTNFVHRFPFVAVSIGFAV-----NKKIEFGVVY 123 +KS + NP D ID +N VS G+ ++ F V Sbjct: 145 KKLRKKSQGSKNPQKYSDKELQYIDAISNKQGELENY-VSDGYKTALTEERRRFCFLVEK 203 Query: 124 SCVEGKMYTARKGKGAFCNGQKLQVSQQ 151 C K A KG QKL + QQ Sbjct: 204 QCAVAKNSAAYHSKGKELLAQKLPLWQQ 231 >5O6V-A nrPDB Length = 496 Score = 27.7 bits (60), Expect = 5.1, Method: Compositional matrix adjust. Identities = 12/31 (38%), Positives = 16/31 (51%) Query: 214 MGIHCWDVAGAGIIVTEAGGVLMDVTGGPFD 244 +G H WD AG ++ G L V GG F+ Sbjct: 416 IGEHAWDFGSAGGFLSSIGKALHTVLGGAFN 446 >3RMJ-A nrPDB Length = 370 Score = 27.7 bits (60), Expect = 5.9, Method: Compositional matrix adjust. Identities = 12/43 (27%), Positives = 25/43 (58%) Query: 17 RQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIK 59 RQAGE V A K ++ + +SP+ + K ++++ +++K Sbjct: 90 RQAGEAVAPAPKKRIHTFIATSPIHMEYKLKMKPKQVIEAAVK 132 >2NQL-A nrPDB Length = 388 Score = 27.7 bits (60), Expect = 6.4, Method: Compositional matrix adjust. Identities = 24/67 (35%), Positives = 29/67 (43%), Gaps = 9/67 (13%) Query: 205 TGG--ADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAER- 261 TGG DA + I WD+AG EAG + D+ GG D V R L R Sbjct: 115 TGGFYVDALAALDIALWDIAG-----QEAGKSIRDLLGGGVDSFPAYVSGLPERTLKARG 169 Query: 262 -IAKEIQ 267 +AK Q Sbjct: 170 ELAKYWQ 176 >4BY7-X nrPDB Length = 146 Score = 27.3 bits (59), Expect = 6.9, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRT--PETVRMVLSN 178 +V +E K+Y GK Q+ + +E++ K+ L E G+ E VR + SN Sbjct: 29 IVPETIEAKLYELPDGKDVISISQEFAHNLEEELYKACLNVEFGTLDKIYTEKVRSLYSN 88 Query: 179 M 179 + Sbjct: 89 L 89 >4BXZ-X nrPDB Length = 594 Score = 26.9 bits (58), Expect = 8.4, Method: Compositional matrix adjust. Identities = 17/61 (27%), Positives = 29/61 (47%), Gaps = 2/61 (3%) Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRT--PETVRMVLSN 178 +V +E K+Y GK Q+ + +E++ K+ L E G+ E VR + SN Sbjct: 253 IVPETIEAKLYELPDGKDVISISQEFAHNLEEELYKACLNVEFGTLDKIYTEKVRSLYSN 312 Query: 179 M 179 + Sbjct: 313 L 313 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1IMD-A nrPDB 394 e-110 2BJI-A nrPDB 383 e-107 4AS5-A nrPDB 378 e-105 2CZH-A nrPDB 344 3e-95 6IB8-A nrPDB 261 2e-70 5ZHH-A nrPDB 261 2e-70 5J16-A nrPDB 260 6e-70 2P3V-A nrPDB 239 1e-63 2PCR-A nrPDB 236 1e-62 5EQA-A nrPDB 231 3e-61 3LV0-A nrPDB 230 5e-61 4N81-A nrPDB 229 1e-60 3QMF-A nrPDB 196 8e-51 4O7I-A nrPDB 195 2e-50 1JP4-A nrPDB 189 1e-48 5YHT-A nrPDB 186 1e-47 2WEF-A nrPDB 185 2e-47 1VDW-A nrPDB 181 3e-46 1XI6-A nrPDB 176 1e-44 2Q74-A nrPDB 174 3e-44 4QXD-A nrPDB 173 8e-44 1G0H-A nrPDB 168 2e-42 1LBZ-A nrPDB 151 4e-37 1KA0-A nrPDB 149 1e-36 3B8B-A nrPDB 144 5e-35 5ESY-A nrPDB 139 1e-33 Sequences not found previously or not previously below threshold: 5DJK-A nrPDB 81 8e-16 1INP-A nrPDB 67 7e-12 1SPI-A nrPDB 36 0.014 2F3D-A nrPDB 34 0.086 5IZ1-A nrPDB 33 0.13 2FHY-A nrPDB 33 0.15 1BK4-A nrPDB 33 0.19 1DCU-A nrPDB 32 0.35 5Q0C-A nrPDB 31 0.51 5FGU-A nrPDB 30 0.92 3BDN-A nrPDB 30 1.6 3C94-A nrPDB 29 2.4 4MB4-A nrPDB 29 3.1 4W5Z-A nrPDB 28 4.3 3K85-A nrPDB 28 4.6 4LD0-A nrPDB 28 4.6 5Y88-O nrPDB 27 7.1 >1IMD-A nrPDB Length = 277 Score = 394 bits (1013), Expect = e-110, Method: Composition-based stats. Identities = 277/277 (100%), Positives = 277/277 (100%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE Sbjct: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 Query: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG Sbjct: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME Sbjct: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 Query: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG Sbjct: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 Query: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED 277 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED Sbjct: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED 277 >2BJI-A nrPDB Length = 277 Score = 383 bits (983), Expect = e-107, Method: Composition-based stats. Identities = 245/277 (88%), Positives = 264/277 (95%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 MADPWQECMDYAVTLA QAGEVV EA+KNEMN+M+KSSP DLVTATDQKVEKMLI+SIKE Sbjct: 1 MADPWQECMDYAVTLAGQAGEVVREALKNEMNIMVKSSPADLVTATDQKVEKMLITSIKE 60 Query: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVH FPFVAVSIGF VNKK+EFG Sbjct: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHGFPFVAVSIGFVVNKKMEFG 120 Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 +VYSC+E KMYT RKGKGAFCNGQKLQVS QEDITKSLLVTELGSSRTPETVR++LSN+E Sbjct: 121 IVYSCLEDKMYTGRKGKGAFCNGQKLQVSHQEDITKSLLVTELGSSRTPETVRIILSNIE 180 Query: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 +L C+P+HGIR VGTAA+NMCLVA G ADAYYEMGIHCWDVAGAGIIVTEAGGVL+DVTG Sbjct: 181 RLLCLPIHGIRGVGTAALNMCLVAAGAADAYYEMGIHCWDVAGAGIIVTEAGGVLLDVTG 240 Query: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDED 277 GPFDLMSRRVIA++N+ LAERIAKEIQ+IPLQRDDED Sbjct: 241 GPFDLMSRRVIASSNKTLAERIAKEIQIIPLQRDDED 277 >4AS5-A nrPDB Length = 277 Score = 378 bits (971), Expect = e-105, Method: Composition-based stats. Identities = 239/276 (86%), Positives = 261/276 (94%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 MADPWQECMDYAV LARQAGE++ EA+KNEM+VM+KSSP DLVT TDQKVEKML+SSIKE Sbjct: 1 MADPWQECMDYAVILARQAGEMIREALKNEMDVMIKSSPADLVTVTDQKVEKMLMSSIKE 60 Query: 61 KYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 KYP HSFIGEESVAAGEK++ T+ PTW+IDPIDGTTNFVHRFPFVAVSIGF VNK++EFG Sbjct: 61 KYPCHSFIGEESVAAGEKTVFTEQPTWVIDPIDGTTNFVHRFPFVAVSIGFLVNKEMEFG 120 Query: 121 VVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNME 180 +VYSCVE KMYT RKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSR PET+R+VLSNME Sbjct: 121 IVYSCVEDKMYTGRKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRKPETLRIVLSNME 180 Query: 181 KLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG 240 KL IP+HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWD+AGAGIIVTEAGGVLMDVTG Sbjct: 181 KLCSIPIHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDMAGAGIIVTEAGGVLMDVTG 240 Query: 241 GPFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 GPFDLMSRR+IAAN+ LA+RIAKEI++IPLQRDDE Sbjct: 241 GPFDLMSRRIIAANSITLAKRIAKEIEIIPLQRDDE 276 >2CZH-A nrPDB Length = 299 Score = 344 bits (882), Expect = 3e-95, Method: Composition-based stats. Identities = 147/275 (53%), Positives = 209/275 (76%) Query: 2 ADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61 A PW+EC AV LA +AG+++ +A+ E V K+S DLVT TD VE ++IS ++E+ Sbjct: 24 AGPWEECFQAAVQLALRAGQIIRKALTEEKRVSTKTSAADLVTETDHLVEDLIISELRER 83 Query: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121 +PSH FI EE+ A+G K +LT +PTWIIDPIDGT NFVHRFP VAVSIGFAV +++EFGV Sbjct: 84 FPSHRFIAEEAAASGAKCVLTHSPTWIIDPIDGTCNFVHRFPTVAVSIGFAVRQELEFGV 143 Query: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181 +Y C E ++YT R+G+GAFCNGQ+L+VS + D++K+L++TE+G R P T+++ LSNME+ Sbjct: 144 IYHCTEERLYTGRRGRGAFCNGQRLRVSGETDLSKALVLTEIGPKRDPATLKLFLSNMER 203 Query: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 L HG+R +G++ + +C +A+G ADAYY+ G+HCWD+A A +I+ EAGG+++D +GG Sbjct: 204 LLHAKAHGVRVIGSSTLALCHLASGAADAYYQFGLHCWDLAAATVIIREAGGIVIDTSGG 263 Query: 242 PFDLMSRRVIAANNRILAERIAKEIQVIPLQRDDE 276 P DLM+ RV+AA+ R +A IA+ +Q I RDDE Sbjct: 264 PLDLMACRVVAASTREMAMLIAQALQTINYGRDDE 298 >6IB8-A nrPDB Length = 271 Score = 261 bits (668), Expect = 2e-70, Method: Composition-based stats. Identities = 84/257 (32%), Positives = 141/257 (54%), Gaps = 6/257 (2%) Query: 9 MDYAVTLARQAGEVVCEAIKNEMNVM-LKSSPVDLVTATDQKVEKMLISSIKEKYPSHSF 67 ++ AV AR+AG ++ + + V + D VT D+ E ++I +I++ YP H+ Sbjct: 9 LNIAVRAARKAGNLIAKNYETPDAVEASQKGSNDFVTNVDKAAEAVIIDTIRKSYPQHTI 68 Query: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 127 I EES GE + W+IDP+DGTTNF+ R P AVSI + + E VVY + Sbjct: 69 ITEES---GELEGTDQDVQWVIDPLDGTTNFIKRLPHFAVSIAVRIKGRTEVAVVYDPMR 125 Query: 128 GKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPV 187 +++TA +G+GA NG +L+ S D+ ++L T + + ++ + KLF Sbjct: 126 NELFTATRGQGAQLNGYRLRGSTARDLDGTILATGF-PFKAKQYATTYINIVGKLFN-EC 183 Query: 188 HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMS 247 R G+AA+++ VA G D ++E+G+ WD A ++V EAGG++ D TGG +++ Sbjct: 184 ADFRRTGSAALDLAYVAAGRVDGFFEIGLRPWDFAAGELLVREAGGIVSDFTGGHNYMLT 243 Query: 248 RRVIAANNRILAERIAK 264 ++A N R++ +A Sbjct: 244 GNIVAGNPRVVKAMLAN 260 >5ZHH-A nrPDB Length = 270 Score = 261 bits (667), Expect = 2e-70, Method: Composition-based stats. Identities = 86/247 (34%), Positives = 126/247 (51%), Gaps = 11/247 (4%) Query: 28 KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTW 87 K E + K P DLVTA D+ E +++ I+ +P HS + EES G + + W Sbjct: 28 KLEDAITEKGRPGDLVTAADKASEAVVLEIIRRHFPQHSILAEESGKLGNQ---DNEYLW 84 Query: 88 IIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQ 147 IDP+DGTTN+ H++P VSIG +N + GV+Y +++ G GA N + ++ Sbjct: 85 AIDPLDGTTNYAHQYPAFCVSIGLLINGVPQVGVIYDPFHDELFRGAAGLGATRNRRPIK 144 Query: 148 VSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVH---GIRSVGTAAVNMCLVA 204 VS +++KSLLVT R R N FC H G+R G+AA+++ VA Sbjct: 145 VSDTSELSKSLLVTGFAYDR-----RETPDNNYAEFCHLTHLTQGVRRSGSAALDLAHVA 199 Query: 205 TGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAERIAK 264 G D Y+E GI WDV I++ EAGG + P + + R++A N I Sbjct: 200 CGRVDGYWERGISPWDVVAGVILLEEAGGKVTAYDSTPLKIATGRILATNGSIHDNLSRA 259 Query: 265 EIQVIPL 271 +QV PL Sbjct: 260 LMQVPPL 266 >5J16-A nrPDB Length = 283 Score = 260 bits (663), Expect = 6e-70, Method: Composition-based stats. Identities = 76/255 (29%), Positives = 125/255 (49%), Gaps = 7/255 (2%) Query: 11 YAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 +A L ++AG + + ++ + + KS+P DLVT D+ E + +I E YP+H +GE Sbjct: 14 FAQGLIQEAGIRIKQLMEQNLTIETKSNPNDLVTNVDKATEDFIFDTILETYPNHQVLGE 73 Query: 71 ESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKM 130 E G + W++DPIDGT NFVH+ A+SIG ++ K G VY + + Sbjct: 74 EG--HGHDIDTSKGTVWVVDPIDGTLNFVHQQENFAISIGIYIDGKPYAGFVYDVMADVL 131 Query: 131 YTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGI 190 Y A+ G+GA+ Q L+ ++ +S++ P +L + K Sbjct: 132 YHAKVGEGAYRGSQPLKPLNDSNLRQSIIGINPNWLTKP-----ILGEIFKEIVNDSRSA 186 Query: 191 RSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRV 250 R+ G+AA+ + VATG +AY + WD AG +I+ E G ++ G P + Sbjct: 187 RAYGSAALEIVSVATGNLEAYMTPRLQPWDFAGGLVILYEVNGQASNLLGEPLTISGPNS 246 Query: 251 IAANNRILAERIAKE 265 I NR L + I+ + Sbjct: 247 ILVGNRGLHQEISND 261 >2P3V-A nrPDB Length = 256 Score = 239 bits (609), Expect = 1e-63, Method: Composition-based stats. Identities = 74/253 (29%), Positives = 130/253 (51%), Gaps = 14/253 (5%) Query: 7 ECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHS 66 + +D+++ L R+ G ++ NV K+ D+VT D++ ++M++ I++ +P + Sbjct: 2 DRLDFSIKLLRKVGHLLMIHWGRVDNVEKKTGFKDIVTEIDREAQRMIVDEIRKFFPDEN 61 Query: 67 FIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCV 126 + EE + + WIIDPIDGT NFVH P ++S+ + N +++ GVV++ Sbjct: 62 IMAEEGIFE------KGDRLWIIDPIDGTINFVHGLPNFSISLAYVENGEVKLGVVHAPA 115 Query: 127 EGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIP 186 + A +G GAF NG++++VS+ + + + T + + MEK Sbjct: 116 LNETLYAEEGSGAFFNGERIRVSENASLEECVGSTGSYV----DFTGKFIERMEK----R 167 Query: 187 VHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLM 246 IR +G+AA+N V G D + I+ WD+A IIV EAGG++ D +G + Sbjct: 168 TRRIRILGSAALNAAYVGAGRVDFFVTWRINPWDIAAGLIIVKEAGGMVTDFSGKEANAF 227 Query: 247 SRRVIAANNRILA 259 S+ I +N I Sbjct: 228 SKNFIFSNGLIHD 240 >2PCR-A nrPDB Length = 264 Score = 236 bits (601), Expect = 1e-62, Method: Composition-based stats. Identities = 80/261 (30%), Positives = 129/261 (49%), Gaps = 13/261 (4%) Query: 6 QECMDYAVTLARQAGEVVCEAIKNEM--NVMLKSSPVDLVTATDQKVEKMLISSIKEKYP 63 ++ ++ A A G+V+ E N+ K D V+ D+ E+ + I + +P Sbjct: 5 KKYLEVAKIAALAGGQVLKENFGKVKKENIEEKGEK-DFVSYVDKTSEERIKEVILKFFP 63 Query: 64 SHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVY 123 H +GEE A G S W IDP+DGT N+++ FP AVS+G ++ G VY Sbjct: 64 DHEVVGEEMGAEGSGS----EYRWFIDPLDGTKNYINGFPIFAVSVGLVKGEEPIVGAVY 119 Query: 124 SCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLF 183 K+Y KG GA+ NG++++V E + + +V SR+ + + L+ + +F Sbjct: 120 LPYFDKLYWGAKGLGAYVNGKRIKVKDNESLKHAGVVYGF-PSRSRRDISIYLNIFKDVF 178 Query: 184 CIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPF 243 V +R G AAV++C+VA G D E + WD+ +I+ EAGGV + G PF Sbjct: 179 Y-EVGSMRRPGAAAVDLCMVAEGIFDGMMEFEMKPWDITAGLVILKEAGGVYT-LVGEPF 236 Query: 244 DLMSRRVIAANNRILAERIAK 264 + I A N+ L + I + Sbjct: 237 GVSD---IIAGNKALHDFILQ 254 >5EQA-A nrPDB Length = 277 Score = 231 bits (588), Expect = 3e-61, Method: Composition-based stats. Identities = 62/267 (23%), Positives = 116/267 (43%), Gaps = 18/267 (6%) Query: 10 DYAVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFI 68 D A A AG+V+ + KN +++ K+ + VT DQ E+ ++S I + +PSH+ Sbjct: 19 DVANKAANAAGDVIRKYFRKNNFDIIHKND-LSPVTIADQSAEEAMVSVILDNFPSHAVY 77 Query: 69 GEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEG 128 GEE ++ + + W++DPIDGT +F+ P I N G++ V Sbjct: 78 GEEKGWRCKQ--DSADYVWVLDPIDGTKSFITGKPLFGTLIALLQNGTPILGIIDQPVLK 135 Query: 129 KMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVH 188 + + GK NGQ++ D++++ L T + + + +K+ Sbjct: 136 ERWIGITGKRTTLNGQEVSTRTCADLSQAYLYTTSPHLFSGDAEEAFIRVRDKVKIP--- 192 Query: 189 GIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTG-------G 241 G L+++G D E G+ +D ++ +GGV+ D G Sbjct: 193 ---LYGCDCYAYALLSSGFVDLVVESGLKPYDFLALIPVIEGSGGVITDWKGHQLRWEAS 249 Query: 242 PFDL-MSRRVIAANNRILAERIAKEIQ 267 P + S V+AA ++ + ++ +Q Sbjct: 250 PLSIATSFNVVAAGDKQIHQQALDSLQ 276 >3LV0-A nrPDB Length = 267 Score = 230 bits (586), Expect = 5e-61, Method: Composition-based stats. Identities = 86/266 (32%), Positives = 133/266 (50%), Gaps = 10/266 (3%) Query: 4 PWQECMDYAVTLARQAGEVVCEAIK--NEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61 P M+ V A +AG + + V LK P D V+ D+K EK++ + + + Sbjct: 6 PQSAVMNVMVQAAMKAGRSLVRDYGEVQNLQVSLKG-PADYVSQADRKAEKIIFNELSKA 64 Query: 62 YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGV 121 P F+ EES E +I+DP+DGTTNF+H PF AVSI KI GV Sbjct: 65 RPKFGFLMEES---EEIIGEDSQHRFIVDPLDGTTNFLHGIPFFAVSIALESQGKIVAGV 121 Query: 122 VYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEK 181 +Y+ + +++TA +G GAF N ++ +VS + + ++ T + P ++ + Sbjct: 122 IYNPINDELFTAERGSGAFFNDRRCRVSARRRLEDCVIATGMPHLGRPGHGTYLIE--LR 179 Query: 182 LFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGG 241 V GIR GTAA+++ VA G D ++E + WD+A ++V EAGG + D GG Sbjct: 180 NVMAEVSGIRRFGTAALDLAYVAAGRTDGFWEDNLQIWDMAAGILMVREAGGFVTDKEGG 239 Query: 242 PFDLMSRRVIAANN--RILAERIAKE 265 + +IA N RI ER K+ Sbjct: 240 NDIFRKKNIIAGNEHIRIKLERALKK 265 >4N81-A nrPDB Length = 259 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 58/265 (21%), Positives = 106/265 (40%), Gaps = 12/265 (4%) Query: 5 WQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPS 64 +++ + A LA A +++ + + + LK+ VT D+ E+ + + ++++ P Sbjct: 6 YEDDIRLAHRLADVAADIIRPFFRAPLTIDLKADHS-PVTKADRGAEQAMRAILEQERPE 64 Query: 65 HSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYS 124 GEE + W++DPIDGT F+ I + + G++ Sbjct: 65 DGIFGEEMGVS----RPDARRLWVLDPIDGTRAFIGGRASFGTLIALVEDGRPVLGIINQ 120 Query: 125 CVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFC 184 + + + K NG+ + + +LL T S E V + +L C Sbjct: 121 PIHQERWVGVKDLPTSFNGEVIHTRSCPALDHALLATT--SPWLFEKEGEVHFDKIRLKC 178 Query: 185 IPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFD 244 +G N L++ G D E G+ +D A IV AGG++ D P + Sbjct: 179 RDT----LLGGDCYNYGLLSLGHCDLVVEQGLKFYDFAALVPIVEGAGGIMRDWQNRPLN 234 Query: 245 LMS-RRVIAANNRILAERIAKEIQV 268 S VIAA + L E +++ Sbjct: 235 KNSVGEVIAAGDHHLIEPALSAMEL 259 >3QMF-A nrPDB Length = 273 Score = 196 bits (499), Expect = 8e-51, Method: Composition-based stats. Identities = 60/260 (23%), Positives = 104/260 (40%), Gaps = 21/260 (8%) Query: 17 RQAGEVVCEAIKN----------EMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHS 66 +Q +++C +K EM K DLVT D+++++ + +P H Sbjct: 15 QQIDKLICSWLKQIDNVIPQLIMEMTTETKRHRFDLVTNVDKQIQQQFQQFLATYFPEHQ 74 Query: 67 FIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCV 126 + EE A + + N WI+DPIDGT N V + + + + K VY Sbjct: 75 LLAEEKSNAMITNEI--NHLWIMDPIDGTANLVKQQEDYCIILAYFYEGKPMLSYVYDYP 132 Query: 127 EGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIP 186 K+Y A +G+GAFCNG K++ + +++ + M L ++ LF Sbjct: 133 HKKLYKAIRGEGAFCNGIKMEEPPSLKLEDAII--------SFNAQVMNLDTVQDLFDAS 184 Query: 187 VHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLM 246 R VG ++ VA G A+ WD+A + + + G D + Sbjct: 185 F-SYRLVGACGLDSMRVAKGQFGAHINTNPKPWDIAAQFLFAELLNLKMTTLDGKAIDHL 243 Query: 247 SRRVIAANNRILAERIAKEI 266 +N+ E + K + Sbjct: 244 KGAPFIISNKACHETVLKIL 263 >4O7I-A nrPDB Length = 325 Score = 195 bits (495), Expect = 2e-50, Method: Composition-based stats. Identities = 73/319 (22%), Positives = 118/319 (36%), Gaps = 63/319 (19%) Query: 9 MDYAVTLARQAGEVVCE--------AIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 D + LA + +V C+ + ++ + SP VT D V+ + I E Sbjct: 3 FDKELALALEIVQVSCKITTSVAEHTLTDQTQIKNDKSP---VTVGDYSVQAYVNKKIHE 59 Query: 61 KYPSHSFIGEESVAAG-----------------------EKSILTDNPT------WIIDP 91 +P + EE KSI N T W++DP Sbjct: 60 TFPEDQIVAEEDTKTIPEDIFAKVCKHVQIYSDMKDDEIRKSIDLGNSTGGKGRHWVLDP 119 Query: 92 IDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE---GKMYTARKGKGA-------FC 141 IDGT F+ R AV + F ++ I+ GV+ C G + A+KG GA Sbjct: 120 IDGTLGFLRREQ-YAVCLAFMIDGDIKVGVL-GCPNFEGGLIVAAQKGCGAKMFSVNDIK 177 Query: 142 NGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMC 201 NG+ + VS + + S T ++ ++ ++ PV Sbjct: 178 NGKDIHVSTTPKTSDMCFCESVEVSHTDQSRSKTITERLQVTKPPVRMDSQC-----KYM 232 Query: 202 LVATGGADAYYEMGI------HCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANN 255 +A+G AD Y + WD A +IV EAGG + D+ G D R + N+ Sbjct: 233 AIASGRADVYLRLPRNLSYQEKIWDHAAGYLIVKEAGGKVTDIYGNDLDFSLGRTLCNNH 292 Query: 256 RILAERIAKEIQVIPLQRD 274 I+A + + + +D Sbjct: 293 GIVASNGILHEETVNVVKD 311 >1JP4-A nrPDB Length = 308 Score = 189 bits (479), Expect = 1e-48, Method: Composition-based stats. Identities = 73/307 (23%), Positives = 119/307 (38%), Gaps = 69/307 (22%) Query: 12 AVTLARQAGEVV-CEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 A ++A++AG +V C + ++ ++ K+S DL T D+ V+ + SS+ K+P + IGE Sbjct: 15 AYSIAQKAGTIVRCVIAEGDLGIVQKTSATDLQTKADRMVQMSICSSLSRKFPKLTIIGE 74 Query: 71 ESVAAGE-----------------------KSILTDNPTWIIDPIDGTTNFVHR-FPFVA 106 E + GE +I ++ +DP+DGT + V Sbjct: 75 EDLPPGEVDQELIEDGQSEEILKQPCPSQYSAIKEEDLVVWVDPVDGTKEYTEGLLDNVT 134 Query: 107 VSIGFAVNKKIEFGVVYSC----------VEGKMYTARKGKGAFCNGQKLQVSQQEDITK 156 V IG A K G++ V G+ G GAF K + + IT Sbjct: 135 VLIGIAYEGKAIAGIINQPYYNYQAGPDAVLGRTIWGVLGLGAFGFQLKEAPAGKHIITT 194 Query: 157 SL-----LVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAY 211 + LVT+ ++ P+ + VG A + + G A AY Sbjct: 195 TRSHSNKLVTDCIAAMNPDN------------------VLRVGGAGNKIIQLIEGKASAY 236 Query: 212 YEMGIHC--WDVAGAGIIVTEAGGVLMDVTGGPFD-------LMSRRVIAA--NNRILAE 260 C WD +I+ GG L D+ G P + S V+AA N A Sbjct: 237 VFASPGCKKWDTCAPEVILHAVGGKLTDIHGNPLQYDKEVKHMNSAGVLAALRNYEYYAS 296 Query: 261 RIAKEIQ 267 R+ + ++ Sbjct: 297 RVPESVK 303 >5YHT-A nrPDB Length = 267 Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 67/269 (24%), Positives = 112/269 (41%), Gaps = 24/269 (8%) Query: 7 ECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSP-VDLVTATDQKVEKMLISSIKEKYPSH 65 + + A+ LA +A E+ +++ + + P + VT D+ VE + ++ P Sbjct: 11 DDLMLALALADRADELTRVRF-GALDLRIDTKPDLTPVTDADRAVESDVRQTLGRDRPGD 69 Query: 66 SFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSC 125 +GEE + WI+DPIDGT NFV P A I + GVV + Sbjct: 70 GVLGEEFGGS----TTFTGRQWIVDPIDGTKNFVRGVPVWASLIALLEDGVPSVGVVSAP 125 Query: 126 VEGKMYTARKGKGAFCN-----GQKLQVSQQEDITKSLLVTELGSSRT-PETVRMVLSNM 179 + + A +G+GAF + +L VS ++ + L S P + Sbjct: 126 ALQRRWWAARGRGAFASVDGARPHRLSVSSVAELHSASLSFSSLSGWARPGLRERFIGLT 185 Query: 180 EKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVT 239 + ++ + +G ++ CLVA G D E + WD+A I+V EAGG L + Sbjct: 186 DTVWRVRAYG------DFLSYCLVAEGAVDIAAEPQVSVWDLAALDIVVREAGGRLTSLD 239 Query: 240 G--GPFDLMSRRVIAANNRILAERIAKEI 266 G GP A N +L + + + Sbjct: 240 GVAGP----HGGSAVATNGLLHDEVLTRL 264 >2WEF-A nrPDB Length = 311 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 71/307 (23%), Positives = 115/307 (37%), Gaps = 69/307 (22%) Query: 12 AVTLARQAGEVVCEAI-KNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGE 70 A ++A++AG +V I + ++ ++ K+ DL T D+ + + SS+ K+P + IGE Sbjct: 11 AYSIAQKAGMIVRRVIAEGDLGIVEKTCATDLQTKADRLAQMSICSSLARKFPKLTIIGE 70 Query: 71 ESVAAGE-KSILTDNPTW----------------------IIDPIDGTTNFVHR-FPFVA 106 E + + E L ++ W +DP+DGT + V Sbjct: 71 EDLPSEEVDQELIEDSQWEEILKQPCPSQYSAIKEEDLVVWVDPLDGTKEYTEGLLDNVT 130 Query: 107 VSIGFAVNKKIEFGVVYSC----------VEGKMYTARKGKGAFCNGQKLQVSQQEDITK 156 V IG A K GV+ V G+ G GAF K + + IT Sbjct: 131 VLIGIAYEGKAIAGVINQPYYNYEAGPDAVLGRTIWGVLGLGAFGFQLKEVPAGKHIITT 190 Query: 157 SL-----LVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAY 211 + LVT+ ++ P+ + VG A + + G A AY Sbjct: 191 TRSHSNKLVTDCVAAMNPDA------------------VLRVGGAGNKIIQLIEGKASAY 232 Query: 212 YEMGIHC--WDVAGAGIIVTEAGGVLMDVTGGPFD-------LMSRRVIAA--NNRILAE 260 C WD +I+ GG L D+ G + S V+A N A Sbjct: 233 VFASPGCKKWDTCAPEVILHAVGGKLTDIHGNVLQYHKDVKHMNSAGVLATLRNYDYYAS 292 Query: 261 RIAKEIQ 267 R+ + I+ Sbjct: 293 RVPESIK 299 >1VDW-A nrPDB Length = 254 Score = 181 bits (459), Expect = 3e-46, Method: Composition-based stats. Identities = 62/267 (23%), Positives = 115/267 (43%), Gaps = 30/267 (11%) Query: 10 DYAVTLARQAGEVVCEAIKNEMNVMLKS-SPV-DLVTATDQKVEKMLISSIKEKYPSHSF 67 A+ + R + N S SP D D+ E ++IS K+ + Sbjct: 8 KIAIDIIRDFDHNIMPLFGNPKASETISISPSGDETKVVDKVAENIIISKFKDL--GVNV 65 Query: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 127 + EE + + T ++DP+DG+ NF++ PF AVS+ K + +Y + Sbjct: 66 VSEEIG----RIDQGSDYTVVVDPLDGSYNFINGIPFFAVSVAIFHEKDPIYAFIYEPIV 121 Query: 128 GKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPV 187 ++Y GKG++ NG+K++V + + T+ ++ + V+ Sbjct: 122 ERLYEGIPGKGSYLNGEKIKVRELAEKPSISFYTKGKGTKIIDKVKRT------------ 169 Query: 188 HGIRSVGTAAVNMCLVATGGADAYYEMG--IHCWDVAGAGIIVTEAGGVLMDVTGGPFDL 245 R++G A+ + +A G DA ++ + D+A +I EAG ++ D+ G ++ Sbjct: 170 ---RTLGAIALELAYLARGALDAVVDIRNYLRPTDIAAGVVIAREAGAIVKDLDGKDVEI 226 Query: 246 M-----SRRVIAANNRILAERIAKEIQ 267 +IAANN L E I + I+ Sbjct: 227 TFSATEKVNIIAANNEELLETILRSIE 253 >1XI6-A nrPDB Length = 262 Score = 176 bits (445), Expect = 1e-44, Method: Composition-based stats. Identities = 61/267 (22%), Positives = 108/267 (40%), Gaps = 29/267 (10%) Query: 10 DYAVTLARQAGEVVCEAIKNEMNVM-LKSSPV-DLVTATDQKVEKMLISSIKEKYPSHSF 67 + A+ + + N +K SP D D+ E +++S I E + Sbjct: 16 EVAIDIISDFETTIMPFFGNPDGGKLVKISPSGDETKLVDKLAEDLILSRITEL--GVNV 73 Query: 68 IGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE 127 + EE +S T I+DP+DG+ NF+ PF A+S+ K + ++Y + Sbjct: 74 VSEEVGVIDNES----EYTVIVDPLDGSYNFIAGIPFFALSLAVFKKDKPIYAIIYEPMT 129 Query: 128 GKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPV 187 + + G+GAF NG++++V + D S+ G V Sbjct: 130 ERFFEGIPGEGAFLNGKRIKVRKTPDEKPSISFYSRGKGH--------------EIVKHV 175 Query: 188 HGIRSVGTAAVNMCLVATGGADAYYEMG--IHCWDVAGAGIIVTEAGGVLMDVTGGPFDL 245 R++G A+ + +A G D ++ + D+A II EAG ++ D G D+ Sbjct: 176 KRTRTLGAIALELAYLAMGALDGVVDVRKYVRPTDIAAGTIIAKEAGALIKDSAGKDIDI 235 Query: 246 M-----SRRVIAANNRILAERIAKEIQ 267 VIA N+ L + I ++ Sbjct: 236 SFNATDRLDVIAVNSEELLKTILSLLE 262 >2Q74-A nrPDB Length = 299 Score = 174 bits (442), Expect = 3e-44, Method: Composition-based stats. Identities = 69/204 (33%), Positives = 105/204 (51%), Gaps = 10/204 (4%) Query: 23 VCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGE-KSIL 81 + A + V KSSP D VT D E++L + + P +GEE + + Sbjct: 36 ISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATP 95 Query: 82 TDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFC 141 +D TW++DPIDGT NFV+ P AVSIG V G V +Y+A G GA Sbjct: 96 SDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHL 155 Query: 142 NGQK----LQVSQQEDITKSLLVTELGSS-RTPETVRMVLSNMEKLFCIPVHGIRSVGTA 196 ++ L+ + ++++ +LL T G S R E +L+++ L V +R +G+A Sbjct: 156 TDERGRHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPL----VRDVRRIGSA 211 Query: 197 AVNMCLVATGGADAYYEMGIHCWD 220 A+++C+VA G DAYYE G+ WD Sbjct: 212 ALDLCMVAAGRLDAYYEHGVQVWD 235 >4QXD-A nrPDB Length = 293 Score = 173 bits (438), Expect = 8e-44, Method: Composition-based stats. Identities = 61/258 (23%), Positives = 104/258 (40%), Gaps = 39/258 (15%) Query: 7 ECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHS 66 E + +T ++A + + K E+ + KS + VT D + ++++ S IK KYP+ + Sbjct: 7 EFANVLITAVKEASYSISK-FKEEVEIKYKSDGSE-VTQVDTQSQQIIFSIIKNKYPTIN 64 Query: 67 FIGEESVAAG------------------EKSILTDNPTWIIDPIDGTTNFVH-RFPFVAV 107 IGEE V G K I ++ +DP+DGT + H ++ V V Sbjct: 65 IIGEEDVENGIPDNQLPTITQLSFGSLENKIININDIIIYVDPLDGTDCYTHKQYDSVCV 124 Query: 108 SIGFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSR 167 +G K G+V + + A N +S Q K + V Sbjct: 125 LVGVTYKGKPMIGIVSKP-----FYNNEITFAIENYIS-SISLQPLNDKIIFVCS----- 173 Query: 168 TPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIH--CWDVAGAG 225 + + ++ K F P + ++ G + M + AD YY I WD A Sbjct: 174 ----KKNDIQHLIKSFPDP-YEVKYKGGSGAKMMAIIHQEADIYYHPLIQSCTWDTLAAQ 228 Query: 226 IIVTEAGGVLMDVTGGPF 243 +I+ GG++ D+ G P Sbjct: 229 VILEAQGGIVCDIYGNPL 246 >1G0H-A nrPDB Length = 252 Score = 168 bits (426), Expect = 2e-42, Method: Composition-based stats. Identities = 65/268 (24%), Positives = 122/268 (45%), Gaps = 31/268 (11%) Query: 10 DYAVTLARQAGEVVCEAI-KNEMNVMLKSSPV-DLVTATDQKVEKMLISSIKEKYPSHSF 67 + +A++ + + + + + ++ +SP D D+ E + + +K + + Sbjct: 5 EIGKNIAKEIEKEILPYFGRKDKSYVVGTSPSGDETEIFDKISEDIALKYLKSL--NVNI 62 Query: 68 IGEESVAAGEKSILTDNPTW--IIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSC 125 + EE ++ ++ W +IDPIDG+ NF++ PF A G N + +G+ Y Sbjct: 63 VSEE------LGVIDNSSEWTVVIDPIDGSFNFINGIPFFAFCFGVFKNNEPYYGLTYEF 116 Query: 126 VEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCI 185 + Y A KGKGA+ NG+K++V +D + +V S+ + + Sbjct: 117 LTKSFYEAYKGKGAYLNGRKIKV---KDFNPNNIVISYYPSKKIDLEK---------LRN 164 Query: 186 PVHGIRSVGTAAVNMCLVATGGADAYYEMGIHC--WDVAGAGIIVTEAGGVLMDVTGG-- 241 V +R G + MC VA G DA +++ D+A + II EAG ++ D G Sbjct: 165 KVKRVRIFGAFGLEMCYVAKGTLDAVFDVRPKVRAVDIASSYIICKEAGALITDENGDEL 224 Query: 242 PFDLMSR---RVIAANNRILAERIAKEI 266 FDL + +I AN++ + + I + Sbjct: 225 KFDLNATDRLNIIVANSKEMLDIILDLL 252 >1LBZ-A nrPDB Length = 252 Score = 151 bits (380), Expect = 4e-37, Method: Composition-based stats. Identities = 64/274 (23%), Positives = 118/274 (43%), Gaps = 45/274 (16%) Query: 12 AVTLARQ-AGEVVCEAIKNEMNVMLK----SSPVDLVTATDQKVEKMLISSIKEKYPSHS 66 A+ ++R+ AGEV + +K A D+ E + ++++ + Sbjct: 6 ALRISREIAGEVRKAIASMPLRERVKDVGMGKDGTPTKAADRVAEDAALEILRKER--VT 63 Query: 67 FIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIE---FGVVY 123 + EES GE + +DP+DGT N P +VS+ F+ + K++ FG VY Sbjct: 64 VVTEESGVLGEGDVFVA-----LDPLDGTFNATRGIPVYSVSLCFSYSDKLKDAFFGYVY 118 Query: 124 SCVEGKMYTARKGKGAFCNGQKLQVSQQEDITKSLLVTELGSSRTPETVRMVLSNMEKLF 183 + G Y A GA+ NG++++VS E++ + ++ Sbjct: 119 NLATGDEYYA-DSSGAYRNGERIEVSDAEELYCNAIIY------------------YPDR 159 Query: 184 CIPVHGIRSVGTAAVNMCLVATGGADAYYEMG----IHCWDVAGAGIIVTEAGGVLMDVT 239 P +R G+AA +C A G D + ++ + +D A I +AGG + ++ Sbjct: 160 KFPFKRMRIFGSAATELCFFADGSFDCFLDIRPGKMLRIYDAAAGVFIAEKAGGKVTELD 219 Query: 240 G-----GPFDLMSR-RVIAANNRILAERIAKEIQ 267 G FD+ R ++AAN + L ++ + I+ Sbjct: 220 GESLGNKKFDMQERLNIVAANEK-LHPKLLELIK 252 >1KA0-A nrPDB Length = 357 Score = 149 bits (375), Expect = 1e-36, Method: Composition-based stats. Identities = 66/352 (18%), Positives = 112/352 (31%), Gaps = 106/352 (30%) Query: 6 QECMDYAVTLARQAGEVVCEAIKN-----EMNVMLKSSPVDLVTATDQKVEKMLISSIKE 60 + + A R+A + + + K+ VT D + ++I++IK Sbjct: 4 ERELLVATQAVRKASLLTKRIQSEVISHKDSTTITKNDNS-PVTTGDYAAQTIIINAIKS 62 Query: 61 KYPSHSFIGEESVAAGEKSILTD------------------------------------- 83 +P +GEES + + ++ Sbjct: 63 NFPDDKVVGEESSSGLSDAFVSGILNEIKANDEVYNKNYKKDDFLFTNDQFPLKSLEDVR 122 Query: 84 -------------NPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSC----- 125 W +DPIDGT F+ AV + V+ ++ G + Sbjct: 123 QIIDFGNYEGGRKGRFWCLDPIDGTKGFLRGEQ-FAVCLALIVDGVVQLGCIGCPNLVLS 181 Query: 126 -----------VEGKMYTARKGKGAFCNGQ-------KLQVSQQEDITKSL---LVTELG 164 G ++ A +G GAF + K+ V +D + V + Sbjct: 182 SYGAQDLKGHESFGYIFRAVRGLGAFYSPSSDAESWTKIHVRHLKDTKDMITLEGVEKGH 241 Query: 165 SSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIH------C 218 SS +T N+ K + + CL+A G AD Y + I Sbjct: 242 SSHDEQTAIKNKLNISKSLHLD---------SQAKYCLLALGLADVYLRLPIKLSYQEKI 292 Query: 219 WDVAGAGIIVTEAGGVLMDVTGG-PFDLMSRRVIA-------ANNRILAERI 262 WD A +IV EAGG+ D P D + R +A + R L + + Sbjct: 293 WDHAAGNVIVHEAGGIHTDAMEDVPLDFGNGRTLATKGVIASSGPRELHDLV 344 >3B8B-A nrPDB Length = 292 Score = 144 bits (362), Expect = 5e-35, Method: Composition-based stats. Identities = 63/238 (26%), Positives = 102/238 (42%), Gaps = 29/238 (12%) Query: 5 WQECMDYAVTLARQAGEVVC---EAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEK 61 +Q A+ A +AGE + E K++ + K+ L T D+K + +++ + E Sbjct: 20 FQSNAMAAIDAALKAGEKILSIYEDPKSDFEIERKADNSPL-TIADRKAHEAIVAILNET 78 Query: 62 -YPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFG 120 +P S G+ A + T WI+DP+DGT F+ R V+I N G Sbjct: 79 PFPVLSEEGKHMDYAVRRGWDT---LWIVDPLDGTKEFIKRNGEFTVNIALVQNAVPVMG 135 Query: 121 VVYSCVEGKMYTARKGKGAF-CNG----QKLQVSQQEDITKS-----------LLVTELG 164 V+Y V+ ++Y A +G GA+ C+G + V+ Q+ I KS + Sbjct: 136 VIYVPVKKELYFAVEGTGAYKCSGIVGLEDEGVTLQQMIEKSERMPLADARDHFIAVASR 195 Query: 165 SSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHC-WDV 221 S TPET + +K + +++ +CLVA G AD Y WD Sbjct: 196 SHLTPETETYIADLKKKHGNVE----LISSGSSIKICLVAEGKADVYPRFAPTMEWDT 249 >5ESY-A nrPDB Length = 346 Score = 139 bits (350), Expect = 1e-33, Method: Composition-based stats. Identities = 65/340 (19%), Positives = 113/340 (33%), Gaps = 95/340 (27%) Query: 5 WQECMDYAVTLARQAGEVVCEAIKN--EMNVMLKSSPVDLVTATDQKVEKMLISSIKEKY 62 +++ +D A A A + + K + +V KS VT D + ++ ++++ Sbjct: 3 YEKELDAAKKAASLAARLCQKVQKALLQSDVQSKSDKS-PVTVADYGSQAVVSLVLEKEL 61 Query: 63 PSHSF--IGEESVAA-------------------------------------------GE 77 S F + EE G Sbjct: 62 SSEPFSLVAEEDSGDLRKDGSQDTLERITKLVNDTLATEESFNGSTLSTDDLLRAIDCGT 121 Query: 78 KSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVVYSCVE---------- 127 + W++DPIDGT F+ AV++G K+ GV+ Sbjct: 122 SEGGPNGRHWVLDPIDGTKGFLRG-DQYAVALGLLEEGKVVLGVLACPNLPLASIAGNNK 180 Query: 128 --------GKMYTARKGKGAFC-------NGQKLQVSQQEDITKSLLVTELGSSRTPETV 172 G ++ A G G + + K+QVS E+ ++ + + + Sbjct: 181 NKSSSDEIGCLFFATIGSGTYMQLLDSKSSPVKVQVSSVENPEEASFFESFEGAHSLHDL 240 Query: 173 RMVLSNMEKLFCIPV-------HGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDVAGAG 225 ++N + PV +G S G A+ + G Y E WD Sbjct: 241 SSSIANKLGVKAPPVRIDSQAKYGALSRGDGAIYLRFPHKG----YRE---KIWDHVAGA 293 Query: 226 IIVTEAGGVLMDVTGGPFDLMSR-------RVIAANNRIL 258 I+VTEAGG++ D G P D +I AN +++ Sbjct: 294 IVVTEAGGIVTDAAGKPLDFSKGKYLDLDTGIIVANEKLM 333 >5DJK-A nrPDB Length = 288 Score = 80.5 bits (197), Expect = 8e-16, Method: Composition-based stats. Identities = 44/215 (20%), Positives = 73/215 (33%), Gaps = 25/215 (11%) Query: 39 PVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNF 98 P L A D++ +L+ ++ + P + + EE A + + L + WIIDP+DGT F Sbjct: 63 PWTLGEAGDRQANSLLLRRLQAERPGDAVLSEE--AHDDLARLKSDRVWIIDPLDGTREF 120 Query: 99 -VHRFPFVAVSIGF---AVNKKIEF--GVVYSCVEGKMYTARKGKGAFCNGQKLQVSQQE 152 AV I + N + E V G + Sbjct: 121 STPGRDDWAVHIALWRRSSNGQPEITDAAVALPARGNVVY----------------RTDT 164 Query: 153 DITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYY 212 + + G+ R + + + ++ S+G+A V G DAY Sbjct: 165 VTSGAAPAGVPGTLRIAVSATRPPAVLHRIRQTLAIQPVSIGSAGAKAMAVIDGYVDAYL 224 Query: 213 EMGIH-CWDVAGAGIIVTEAGGVLMDVTGGPFDLM 246 G WD A ++ AG + G P Sbjct: 225 HAGGQWEWDSAAPAGVMLAAGMHASRLDGSPLRYN 259 >1INP-A nrPDB Length = 400 Score = 67.0 bits (162), Expect = 7e-12, Method: Composition-based stats. Identities = 62/338 (18%), Positives = 96/338 (28%), Gaps = 101/338 (29%) Query: 1 MADPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSS---------PVDLVTATDQKVE 51 M+D QE + + A A C + ++++ VD T D V+ Sbjct: 1 MSDILQELLRVSEKAANIA--RACRQQETLFQLLIEEKKEGEKNKKFAVDFKTLADVLVQ 58 Query: 52 KMLISSIKEKYPSHS--FIGEESVAA----GEKSILTDNPT------------------- 86 +++ +++ K+P GEES GEK I+ PT Sbjct: 59 EVIKENMENKFPGLGKKIFGEESNELTNDLGEKIIMRLGPTEEETVALLSKVLNGNKLAS 118 Query: 87 -------------------------------WIIDPIDGTTNFVH--------------R 101 +DPID T ++ Sbjct: 119 EALAKVVHQDVFFSDPALDSVEINIPQDILGIWVDPIDSTYQYIKGSADITPNQGIFPSG 178 Query: 102 FPFVAVSIGFA--VNKKIEFGVVYSCV----------EGKMYTARKGKGAFCNGQKLQVS 149 V V IG GV+ +G+ Y G + VS Sbjct: 179 LQCVTVLIGVYDIQTGVPLMGVINQPFVSQDLHTRRWKGQCYWGLSYLGTNIHSLLPPVS 238 Query: 150 QQEDITKSLLVTELGSSRTPETVRMVLSNMEK------LFCIPVHGIRSVGTAAVNMCLV 203 + + T+ SS +V+S EK L + I A V Sbjct: 239 TRSNSEAQSQGTQNPSSEGSCRFSVVISTSEKETIKGALSHVCGERIFRAAGAGYKSLCV 298 Query: 204 ATGGADAYYEMGIHC--WDVAGAGIIVTEAGGVLMDVT 239 G AD Y WD A I+ GG ++D+ Sbjct: 299 ILGLADIYIFSEDTTFKWDSCAAHAILRAMGGGMVDLK 336 >1SPI-A nrPDB Length = 358 Score = 36.2 bits (82), Expect = 0.014, Method: Composition-based stats. Identities = 48/296 (16%), Positives = 93/296 (31%), Gaps = 61/296 (20%) Query: 7 ECMDYAVTLARQAGEVVCEAIKNEMNVM-LKSSPVDLVTATDQKVEKMLISSIKEKYPSH 65 C A +L ++AG I+ +N+ +D+V+ + SS Sbjct: 50 ACKQIA-SLVQRAGISNLTGIQGAVNIQGEDQKKLDVVSN-------EVFSSCLRSSGRT 101 Query: 66 SFIG--EESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFA----------- 112 I EE V + + N + DP+DG++N + G Sbjct: 102 GIIASEEEDVPVAVEESYSGNYIVVFDPLDGSSN-IDAAVSTGSIFGIYSPNDECIVDSD 160 Query: 113 VNKKIEFG------VVYSCVEGK--------------MYTARKGKGAFCN------GQKL 146 + + + VV C G ++ GKG + G+ + Sbjct: 161 HDDESQLSAEEQRCVVNVCQPGDNLLAAGYCMYSSSVIFVLTIGKGVYAFTLDPMYGEFV 220 Query: 147 QVSQQEDITKSLLVTEL---GSSRTPETVRMVLSNM-EKLFCIPVHGIRSVGTAAVNM-C 201 S++ I K+ + P+ ++ + ++ E + R +G+ + Sbjct: 221 LTSEKIQIPKAGKIYSFNEGNYKMWPDKLKKYMDDLKEPGESQKPYSSRYIGSLVGDFHR 280 Query: 202 LVATGGADAYYEMGIH-------CWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRV 250 + GG Y ++ A IV +AGG D D+ + Sbjct: 281 TLLYGGIYGYPRDAKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRILDIQPTEI 336 >2F3D-A nrPDB Length = 338 Score = 33.9 bits (76), Expect = 0.086, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 14 TLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESV 73 T R+AG I NV D V D ++I+ +K + + + EE Sbjct: 47 TAVRKAGIAHLYGIAGSTNVT-----GDQVKKLDVLSNDLVINVLKSSFATCVLVSEEDK 101 Query: 74 AAG-EKSILTDNPTWIIDPIDGTTN 97 A + DP+DG++N Sbjct: 102 NAIIVEPEKRGKYVVCFDPLDGSSN 126 >5IZ1-A nrPDB Length = 337 Score = 33.1 bits (74), Expect = 0.13, Method: Composition-based stats. Identities = 18/94 (19%), Positives = 35/94 (37%), Gaps = 11/94 (11%) Query: 7 ECMDYAVTLARQAGEVVCEAIKNEMNVM-LKSSPVDLVTATDQKVEKMLISSIKEKYPSH 65 C A +L ++AG ++ N+ +D+++ + SS Sbjct: 31 ACKQIA-SLVQRAGISNLTGLQGVANIQGEDQKKLDVISN-------EVFSSCLRSSGRT 82 Query: 66 SFIG--EESVAAGEKSILTDNPTWIIDPIDGTTN 97 I EE + + N + DP+DG++N Sbjct: 83 GIIASEEEDTPVAVEESYSGNYIVVFDPLDGSSN 116 >2FHY-A nrPDB Length = 374 Score = 32.8 bits (73), Expect = 0.15, Method: Composition-based stats. Identities = 19/88 (21%), Positives = 33/88 (37%), Gaps = 12/88 (13%) Query: 14 TLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEES- 72 + R+AG I NV D V D ++++ +K + + + EE Sbjct: 83 SAVRKAGIAHLYGIAGSTNVT-----GDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDK 137 Query: 73 ---VAAGEKSILTDNPTWIIDPIDGTTN 97 + EK DP+DG++N Sbjct: 138 HAIIVEPEKR---GKYVVCFDPLDGSSN 162 >1BK4-A nrPDB Length = 337 Score = 32.8 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 19/85 (22%), Positives = 32/85 (37%), Gaps = 6/85 (7%) Query: 14 TLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESV 73 T R+AG I NV D V D ++++ +K + + + EE Sbjct: 46 TAVRKAGIAHLYGIAGSTNVT-----GDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDK 100 Query: 74 AAG-EKSILTDNPTWIIDPIDGTTN 97 A + DP+DG++N Sbjct: 101 NAIIVEPEKRGKYVVCFDPLDGSSN 125 >1DCU-A nrPDB Length = 357 Score = 31.6 bits (70), Expect = 0.35, Method: Composition-based stats. Identities = 41/235 (17%), Positives = 75/235 (31%), Gaps = 59/235 (25%) Query: 70 EESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIG-----FAVNKK--IEFG-- 120 EE V + + N + DP+DG++N AVS G ++ N + +FG Sbjct: 106 EEDVPVAVEESYSGNYIVVFDPLDGSSNL-----DAAVSTGSIFGIYSPNDECLPDFGDD 160 Query: 121 -------------VVYSCVEGK--------------MYTARKGKGAFCN------GQKLQ 147 +V C G ++ GKG F G+ + Sbjct: 161 SDDNTLGTEEQRCIVNVCQPGSNLLAAGYCMYSSSVIFVLTIGKGVFVFTLDPLYGEFVL 220 Query: 148 VSQQEDITKSLLVTELGSSRT---PETVRMVLSNMEKLFCI-PVHGIRSVGTAAVNM-CL 202 + I KS + E ++ + ++++ + R +G+ + Sbjct: 221 TQENLQIPKSGKIYSFNEGNYKLWDENLKKYIDDLKEPGPSGKPYSARYIGSLVGDFHRT 280 Query: 203 VATGGADAYYEMGIH-------CWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRV 250 + GG Y ++ A IV +AGG D D+ + Sbjct: 281 LLYGGIYGYPRDKKSKNGKLRLLYECAPMSFIVEQAGGKGSDGHQRVLDIQPTEI 335 >5Q0C-A nrPDB Length = 339 Score = 31.2 bits (69), Expect = 0.51, Method: Composition-based stats. Identities = 19/91 (20%), Positives = 33/91 (36%), Gaps = 6/91 (6%) Query: 8 CMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSF 67 + + R+AG I +NV D V D ++I+ ++ Y + Sbjct: 41 AIKAISSAVRKAGLAHLYGIAGSVNVT-----GDEVKKLDVLSNSLVINMLQSSYSTCVL 95 Query: 68 IGEE-SVAAGEKSILTDNPTWIIDPIDGTTN 97 + EE A DP+DG++N Sbjct: 96 VSEENKDAIITAKEKRGKYVVCFDPLDGSSN 126 >5FGU-A nrPDB Length = 567 Score = 30.4 bits (67), Expect = 0.92, Method: Composition-based stats. Identities = 14/76 (18%), Positives = 31/76 (40%) Query: 202 LVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAER 261 LV+ +D + + + ++ I + GG+L + + I + + E Sbjct: 436 LVSALSSDGFIDETVRVFNNVAGFNIDYQNGGLLSSTADVDINNVEENEIETTDDEIEEG 495 Query: 262 IAKEIQVIPLQRDDED 277 I E L++D++D Sbjct: 496 IENEPDTDALKKDNKD 511 >3BDN-A nrPDB Length = 236 Score = 29.7 bits (65), Expect = 1.6, Method: Composition-based stats. Identities = 32/159 (20%), Positives = 47/159 (29%), Gaps = 11/159 (6%) Query: 110 GFAVNKKIEFGVVYSCVEGKMYTARKGKGAFCNGQK-LQVSQQEDITKSL--LVTELGSS 166 KK E G+ V KM + G GA NG L + K L V E S Sbjct: 20 AIYEKKKNELGLSQESVADKMGMGQSGVGALFNGINALNAYNAALLAKILKVSVEEFSPS 79 Query: 167 RTPETVRMVLS-----NMEKLFCIPVHGIRSVGTAAVNMCLVATGGADAYYEMGIHCWDV 221 E M + ++ + PV G + + G A+ + D Sbjct: 80 IAREIYEMYEAVSMQPSLRSEYEYPVFSHVQAGMFSPELRTFTKGDAERWVSTTKKASDS 139 Query: 222 AGAGIIVTEAGGVLMDVTGGPFDLMSRRVIAANNRILAE 260 A + G + TG +I + E Sbjct: 140 A---FWLEVEGNSMTAPTGSKPSFPDGMLILVDPEQAVE 175 >3C94-A nrPDB Length = 482 Score = 28.9 bits (63), Expect = 2.4, Method: Composition-based stats. Identities = 10/56 (17%), Positives = 23/56 (41%) Query: 24 CEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKYPSHSFIGEESVAAGEKS 79 A+K + ++ P +T D+++EK+L + +P E+ + Sbjct: 377 RAAMKIVLETEPRNLPALDITFVDKRIEKLLFNYRARNFPGTLDYAEQQRWLEHRR 432 >4MB4-A nrPDB Length = 528 Score = 28.5 bits (62), Expect = 3.1, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 9/69 (13%) Query: 202 LVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVT---GGPFDLMSRRVIAANNRIL 258 L+A GGADA+ E+ D A II L D+ G DL + A +N+ + Sbjct: 90 LIALGGADAHIELTRGDEDALAAEII------RLTDLYGFDGLDIDLQQAAITAKDNQFV 143 Query: 259 AERIAKEIQ 267 K ++ Sbjct: 144 IPAALKMVK 152 >4W5Z-A nrPDB Length = 345 Score = 28.1 bits (61), Expect = 4.3, Method: Composition-based stats. Identities = 20/69 (28%), Positives = 30/69 (43%), Gaps = 9/69 (13%) Query: 202 LVATGGADAYYEMGIHCWDVAGAGIIVTEAGGVLMDVT---GGPFDLMSRRVIAANNRIL 258 L+A GGADA+ E+ D A II L D+ G DL + A +N+ + Sbjct: 112 LIALGGADAHIELTRGDEDALAAEII------RLTDLYGFDGLDIDLEQAAITAKDNQFV 165 Query: 259 AERIAKEIQ 267 K ++ Sbjct: 166 IPAALKMVK 174 >3K85-A nrPDB Length = 357 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 17/99 (17%), Positives = 33/99 (33%), Gaps = 4/99 (4%) Query: 45 ATDQKVEKMLISSIKEKYPSHSFIGEES--VAAGEKSILTDNPTWIIDPIDGTTNFVHR- 101 D+ M++ S + I E+ + G ++ + ID + Sbjct: 191 IVDELESSMVLYFTGRSRSSAAIINEQKKNTSEGNQTAIEAMHKIKQSAIDTKLALLKGD 250 Query: 102 FPFVAVSIGF-AVNKKIEFGVVYSCVEGKMYTARKGKGA 139 A +G NKK G + + + + + G GA Sbjct: 251 VGEFARILGEGWENKKKMAGAITNPMIQEAFDVATGAGA 289 >4LD0-A nrPDB Length = 169 Score = 28.1 bits (61), Expect = 4.6, Method: Composition-based stats. Identities = 21/137 (15%), Positives = 41/137 (29%), Gaps = 22/137 (16%) Query: 3 DPWQECMDYAVTLARQAGEVVCEAIKNEMNVMLKSSPVDLVTATDQKVEKMLISSIKEKY 62 DP + V G + + E+ +K+SP + ++ ++ + Sbjct: 10 DPGITHLGLGVVAVEGKGALKARLLHGEV---VKTSPQEPAKERVGRIHARVLEVLHRFR 66 Query: 63 PSHSFIGEESVAAGEKSILTDNPTWIIDPIDGTTNFVHRFPFVAVSIGFAVNKKIEFGVV 122 P E+VA E+ N + + AV + + Sbjct: 67 P-------EAVAVQEQFFYRQNEL----------AYKVGWALGAVLVAAFEAGVPVYA-- 107 Query: 123 YSCVEGKMYTARKGKGA 139 Y ++ K A G A Sbjct: 108 YGPMQVKQALAGHGHAA 124 >5Y88-O nrPDB Length = 451 Score = 27.4 bits (59), Expect = 7.1, Method: Composition-based stats. Identities = 16/86 (18%), Positives = 31/86 (36%), Gaps = 4/86 (4%) Query: 151 QEDITKSLLVTELGSSRTPETVRMVLSNMEKLFCIPVHGIRSVGTAAVNMCLVATGGADA 210 Q ++ + L+V + + ++ + +R V V+ TG D Sbjct: 103 QPEVAEELIVNRYEKLLSQRPEWHAPWKLSRVINGHLGWVRCVAIDPVDNEWFITGSND- 161 Query: 211 YYEMGIHCWDVAGAGIIVTEAGGVLM 236 + WD+A + T AG V+ Sbjct: 162 ---TTMKVWDLATGKLKTTLAGHVMT 184 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.312 0.131 0.351 Lambda K H 0.267 0.0401 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 9,576,078 Number of Sequences: 36641 Number of extensions: 350872 Number of successful extensions: 1218 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 67 Number of HSP's successfully gapped in prelim test: 22 Number of HSP's that attempted gapping in prelim test: 1039 Number of HSP's gapped (non-prelim): 97 length of query: 277 length of database: 10,336,785 effective HSP length: 96 effective length of query: 181 effective length of database: 6,819,249 effective search space: 1234284069 effective search space used: 1234284069 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 58 (27.0 bits)