BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P29055 (345 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6GYK-M nrPDB 712 0.0 5IYC-M nrPDB 184 7e-47 3K1F-M nrPDB 147 9e-36 5WH1-A nrPDB 105 3e-23 1AIS-B nrPDB 73 2e-13 1RLY-A nrPDB 55 4e-08 6CNF-R nrPDB 42 5e-04 6F41-V nrPDB 42 5e-04 3IWZ-A nrPDB 29 3.2 2M9W-A nrPDB 28 5.9 >6GYK-M nrPDB Length = 345 Score = 712 bits (1838), Expect = 0.0, Method: Compositional matrix adjust. Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR Sbjct: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 Query: 61 SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD 120 SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD Sbjct: 61 SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD 120 Query: 121 KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC 180 KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC Sbjct: 121 KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC 180 Query: 181 RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP 240 RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP Sbjct: 181 RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP 240 Query: 241 RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ 300 RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ Sbjct: 241 RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ 300 Query: 301 TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK 345 TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK Sbjct: 301 TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK 345 >5IYC-M nrPDB Length = 316 Score = 184 bits (466), Expect = 7e-47, Method: Compositional matrix adjust. Identities = 108/298 (36%), Positives = 168/298 (56%), Gaps = 19/298 (6%) Query: 22 LTCPECKVYPPKI-VERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVG 80 +TCP +P I VE + GD++C CGLV+ D+++D SEWRTFSND DPSRVG Sbjct: 13 VTCPN---HPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKAT-KDPSRVG 68 Query: 81 EASNPLLDGNNLSTRIGKGETTDMRFTKELN-KAQGKNVMDKKDNEVQAAFAKITMLCDA 139 ++ NPLL +LST IGKG T F + N K Q + M D + AF +IT + D Sbjct: 69 DSQNPLLSDGDLSTMIGKG-TGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADR 127 Query: 140 AELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVK 199 LP+ + D +K +++K+LKG++ ++I +A + I CR+ V RTFKEI ++ + Sbjct: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRIS 187 Query: 200 TKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQVTTSAEYT 259 KE G+ + IL+ L+ D ++ ++ RFCS+L LP QV +A + Sbjct: 188 KKEIGRCFKL---ILKA------LETSVDLITTGD---FMSRFCSNLCLPKQVQMAATHI 235 Query: 260 AKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILY 317 A+K E+ + G+SPI++A +IY+ T ++G V + TI+ Y+++Y Sbjct: 236 ARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIY 293 >3K1F-M nrPDB Length = 197 Score = 147 bits (370), Expect = 9e-36, Method: Compositional matrix adjust. Identities = 68/68 (100%), Positives = 68/68 (100%) Query: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR Sbjct: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 Query: 61 SEWRTFSN 68 SEWRTFSN Sbjct: 61 SEWRTFSN 68 >5WH1-A nrPDB Length = 211 Score = 105 bits (262), Expect = 3e-23, Method: Compositional matrix adjust. Identities = 63/199 (31%), Positives = 104/199 (52%), Gaps = 12/199 (6%) Query: 119 MDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILI 178 M D + AF +IT + D LP+ + D +K +++K+LKG++ ++I +A + I Sbjct: 2 MSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYI 61 Query: 179 GCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTY 238 CR+ V RTFKEI ++ + KE G+ + IL+ L D MS Sbjct: 62 ACRQEGVPRTFKEICAVSRISKKEIGRCFKL---ILKALETSVDLITTGDFMS------- 111 Query: 239 IPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKV 298 RFCS+L LP QV +A + A+K E+ + G+SPI++A +IY+ T ++ Sbjct: 112 --RFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEI 169 Query: 299 GQTLQVTEGTIKSGYKILY 317 G V + TI+ Y+++Y Sbjct: 170 GDIAGVADVTIRQSYRLIY 188 >1AIS-B nrPDB Length = 200 Score = 73.2 bits (178), Expect = 2e-13, Method: Compositional matrix adjust. Identities = 55/201 (27%), Positives = 96/201 (47%), Gaps = 10/201 (4%) Query: 118 VMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASIL 177 V D + + A +++ + +LP+ V++ A Y+ + ++G+S+ES+MAA + Sbjct: 1 VSDAAERNLAFALSELDRITAQLKLPRHVEEEAARLYREAVRKGLIRGRSIESVMAACVY 60 Query: 178 IGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLT 237 CR +V RT EI + V KE G++ + L + F+K TD Sbjct: 61 AACRLLKVPRTLDEIADIARVDKKEIGRSYRFIARNLNLTPKKLFVK-PTD--------- 110 Query: 238 YIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAK 297 Y+ +F LGL +V A + + +GKSP + ++Y+ LL T + Sbjct: 111 YVNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQRE 170 Query: 298 VGQTLQVTEGTIKSGYKILYE 318 V + +VTE T+++ YK L E Sbjct: 171 VAEVARVTEVTVRNRYKELVE 191 >1RLY-A nrPDB Length = 60 Score = 55.1 bits (131), Expect = 4e-08, Method: Composition-based stats. Identities = 25/49 (51%), Positives = 34/49 (69%), Gaps = 4/49 (8%) Query: 22 LTCPECKVYPPKI-VERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSND 69 +TCP +P I VE + GD++C CGLV+ D+++D SEWRTFSND Sbjct: 13 VTCPN---HPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSND 58 >6CNF-R nrPDB Length = 736 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 39/200 (19%), Positives = 82/200 (41%), Gaps = 16/200 (8%) Query: 115 GKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAA 174 G + ++ ++ + A K+ + A +P+ + D A + YKL ++G+ ++++A+ Sbjct: 69 GSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIAS 128 Query: 175 SILIGCRRAEVARTFKEIQSLIHVKTKEFGKT-LNIMKNILRGKSEDGFLKIDTDNMSGA 233 + + CR+ + + S + V G T L ++K K+ + A Sbjct: 129 CLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVK------------KLHITELPLA 176 Query: 234 QNLTYIPRFCSHLGLP---MQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQ 290 +I F L L ++V A A++ + G+ P IA I L + Sbjct: 177 DPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNN 236 Query: 291 IPITAAKVGQTLQVTEGTIK 310 + T ++ V E T++ Sbjct: 237 LRRTHTEIVAVSHVAEETLQ 256 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 144 KIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEF 203 K+VKD K A ++ D +G+ I A IL+ CR + RT EI ++ HV + Sbjct: 197 KVVKDAVKLAQRMSKDW-MFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETL 255 Query: 204 GKTLNIMKN 212 + LN KN Sbjct: 256 QQRLNEFKN 264 >6F41-V nrPDB Length = 596 Score = 41.6 bits (96), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 39/200 (19%), Positives = 82/200 (41%), Gaps = 16/200 (8%) Query: 115 GKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAA 174 G + ++ ++ + A K+ + A +P+ + D A + YKL ++G+ ++++A+ Sbjct: 69 GSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANNFVQGRRSQNVIAS 128 Query: 175 SILIGCRRAEVARTFKEIQSLIHVKTKEFGKT-LNIMKNILRGKSEDGFLKIDTDNMSGA 233 + + CR+ + + S + V G T L ++K K+ + A Sbjct: 129 CLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVK------------KLHITELPLA 176 Query: 234 QNLTYIPRFCSHLGLP---MQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQ 290 +I F L L ++V A A++ + G+ P IA I L + Sbjct: 177 DPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGIAGACILLACRMNN 236 Query: 291 IPITAAKVGQTLQVTEGTIK 310 + T ++ V E T++ Sbjct: 237 LRRTHTEIVAVSHVAEETLQ 256 Score = 40.0 bits (92), Expect = 0.001, Method: Compositional matrix adjust. Identities = 24/69 (34%), Positives = 35/69 (50%), Gaps = 1/69 (1%) Query: 144 KIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEF 203 K+VKD K A ++ D +G+ I A IL+ CR + RT EI ++ HV + Sbjct: 197 KVVKDAVKLAQRMSKD-WMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETL 255 Query: 204 GKTLNIMKN 212 + LN KN Sbjct: 256 QQRLNEFKN 264 >3IWZ-A nrPDB Length = 230 Score = 28.9 bits (63), Expect = 3.2, Method: Compositional matrix adjust. Identities = 21/88 (23%), Positives = 40/88 (45%), Gaps = 10/88 (11%) Query: 116 KNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAAS 175 K ++D + AF +T + + + D +KE + H + T S + + + Sbjct: 143 KRLLDTTRKASRLAFLDVT-----DRIVRTLHDLSKEPEAMSHPQGTQLRVSRQEL---A 194 Query: 176 ILIGCRRAEVARTFKEIQS--LIHVKTK 201 L+GC R R K++Q+ L+H + K Sbjct: 195 RLVGCSREMAGRVLKKLQADGLLHARGK 222 >2M9W-A nrPDB Length = 63 Score = 28.1 bits (61), Expect = 5.9, Method: Composition-based stats. Identities = 11/31 (35%), Positives = 17/31 (54%) Query: 22 LTCPECKVYPPKIVERFSEGDVVCALCGLVL 52 L+C C+ + R +EG+ VC CGL + Sbjct: 11 LSCANCQTTTTTLWRRNAEGEPVCNACGLYM 41 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6GYK-M nrPDB 542 e-155 5IYC-M nrPDB 409 e-114 5WH1-A nrPDB 256 9e-69 6CNF-R nrPDB 233 1e-61 6F41-V nrPDB 229 1e-60 1AIS-B nrPDB 228 2e-60 3K1F-M nrPDB 137 7e-33 1RLY-A nrPDB 93 3e-19 Sequences not found previously or not previously below threshold: 4ROE-A nrPDB 66 2e-11 1ZP2-A nrPDB 36 0.025 6E8E-B nrPDB 32 0.47 4NST-B nrPDB 30 1.7 5KYJ-A nrPDB 30 1.8 4NQA-B nrPDB 30 1.8 2F00-A nrPDB 30 2.0 6N9E-15 nrPDB 30 2.0 3TTD-A nrPDB 29 2.4 5G4J-A nrPDB 29 3.9 4R12-A nrPDB 28 5.1 6EL3-D nrPDB 28 6.0 1KXU-A nrPDB 27 9.7 >6GYK-M nrPDB Length = 345 Score = 542 bits (1397), Expect = e-155, Method: Composition-based stats. Identities = 345/345 (100%), Positives = 345/345 (100%) Query: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR Sbjct: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 Query: 61 SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD 120 SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD Sbjct: 61 SEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMD 120 Query: 121 KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC 180 KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC Sbjct: 121 KKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGC 180 Query: 181 RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP 240 RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP Sbjct: 181 RRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP 240 Query: 241 RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ 300 RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ Sbjct: 241 RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQ 300 Query: 301 TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK 345 TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK Sbjct: 301 TLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNLPGVEKK 345 >5IYC-M nrPDB Length = 316 Score = 409 bits (1050), Expect = e-114, Method: Composition-based stats. Identities = 108/298 (36%), Positives = 165/298 (55%), Gaps = 19/298 (6%) Query: 22 LTCPECKVYPPKI-VERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVG 80 +TCP +P I VE + GD++C CGLV+ D+++D SEWRTFSND DPSRVG Sbjct: 13 VTCPN---HPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKAT-KDPSRVG 68 Query: 81 EASNPLLDGNNLSTRIGKGETTDMRFTKELN-KAQGKNVMDKKDNEVQAAFAKITMLCDA 139 ++ NPLL +LST IGKG T F + N K Q + M D + AF +IT + D Sbjct: 69 DSQNPLLSDGDLSTMIGKG-TGAASFDEFGNSKYQNRRTMSSSDRAMMNAFKEITTMADR 127 Query: 140 AELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVK 199 LP+ + D +K +++K+LKG++ ++I +A + I CR+ V RTFKEI ++ + Sbjct: 128 INLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEICAVSRIS 187 Query: 200 TKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLPMQVTTSAEYT 259 KE G+ + IL+ L D ++ RFCS+L LP QV +A + Sbjct: 188 KKEIGRCFKL---ILKALETSVDLITTGD---------FMSRFCSNLCLPKQVQMAATHI 235 Query: 260 AKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKILY 317 A+K E+ + G+SPI++A +IY+ T ++G V + TI+ Y+++Y Sbjct: 236 ARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKEIGDIAGVADVTIRQSYRLIY 293 Score = 56.7 bits (135), Expect = 1e-08, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 39/94 (41%), Gaps = 2/94 (2%) Query: 239 IPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKV 298 I + LP + K+ E K + G++ IA +Y+ +P T ++ Sbjct: 121 ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEI 180 Query: 299 GQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANG 332 ++++ I +K++ + + VD LI G Sbjct: 181 CAVSRISKKEIGRCFKLILKALETSVD--LITTG 212 >5WH1-A nrPDB Length = 211 Score = 256 bits (654), Expect = 9e-69, Method: Composition-based stats. Identities = 61/200 (30%), Positives = 104/200 (52%), Gaps = 12/200 (6%) Query: 118 VMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASIL 177 M D + AF +IT + D LP+ + D +K +++K+LKG++ ++I +A + Sbjct: 1 SMSSSDRAMMNAFKEITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLY 60 Query: 178 IGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLT 237 I CR+ V RTFKEI ++ + KE G+ + IL+ L D Sbjct: 61 IACRQEGVPRTFKEICAVSRISKKEIGRCFKL---ILKALETSVDLITTGD--------- 108 Query: 238 YIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAK 297 ++ RFCS+L LP QV +A + A+K E+ + G+SPI++A +IY+ T + Sbjct: 109 FMSRFCSNLCLPKQVQMAATHIARKAVELDLVPGRSPISVAAAAIYMASQASAEKRTQKE 168 Query: 298 VGQTLQVTEGTIKSGYKILY 317 +G V + TI+ Y+++Y Sbjct: 169 IGDIAGVADVTIRQSYRLIY 188 Score = 56.3 bits (134), Expect = 2e-08, Method: Composition-based stats. Identities = 19/94 (20%), Positives = 39/94 (41%), Gaps = 2/94 (2%) Query: 239 IPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKV 298 I + LP + K+ E K + G++ IA +Y+ +P T ++ Sbjct: 16 ITTMADRINLPRNIVDRTNNLFKQVYEQKSLKGRANDAIASACLYIACRQEGVPRTFKEI 75 Query: 299 GQTLQVTEGTIKSGYKILYEHRDKLVDPQLIANG 332 ++++ I +K++ + + VD LI G Sbjct: 76 CAVSRISKKEIGRCFKLILKALETSVD--LITTG 107 >6CNF-R nrPDB Length = 736 Score = 233 bits (593), Expect = 1e-61, Method: Composition-based stats. Identities = 52/299 (17%), Positives = 105/299 (35%), Gaps = 46/299 (15%) Query: 24 CPECKVYPPKIVERFSEG--DVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGE 81 C C + + S D+VC CG+V D + + + S Sbjct: 4 CKNC--HGTEFERDLSNANNDLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQ------- 54 Query: 82 ASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAE 141 + IG G++ G + ++ ++ + A K+ + A Sbjct: 55 -----------GSFIGAGQSHAA--------FGGSSALESREATLNNARRKLRAVSYALH 95 Query: 142 LPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTK 201 +P+ + D A + YKL ++G+ ++++A+ + + CR+ + + S + V Sbjct: 96 IPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVY 155 Query: 202 EFGKTL-NIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLGLP---MQVTTSAE 257 G T ++K K+ + A +I F L L ++V A Sbjct: 156 SIGATFLKMVK------------KLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAV 203 Query: 258 YTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKIL 316 A++ + G+ P IA I L + + T ++ V E T++ Sbjct: 204 KLAQRMSKDWMFEGRRPAGIAGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEF 262 Score = 45.1 bits (105), Expect = 5e-05, Method: Composition-based stats. Identities = 42/220 (19%), Positives = 80/220 (36%), Gaps = 18/220 (8%) Query: 126 VQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEV 185 + A KI ++ DA +L + + +K+ +G+ I A IL+ CR + Sbjct: 189 LDLADKKIKVVKDAVKLAQRM---SKDW--------MFEGRRPAGIAGACILLACRMNNL 237 Query: 186 ARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP----- 240 RT EI ++ HV + + LN KN K + + A+ +++ Sbjct: 238 RRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKE 297 Query: 241 -RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVG 299 + L TS E K + ++ G+ ++ V YL + ++ Sbjct: 298 RKIKDSLDKEEMFQTS-EEALNKNPILTQVLGEQELSSKEVLFYLKQFSERRARVVERIK 356 Query: 300 QTLQVTEGTIKSGYKILYEHRDKLVDPQLIANGVVSLDNL 339 T + I + KL + + V +L N+ Sbjct: 357 ATNGIDGENIYHEGSENETRKRKLSEAMPWSGIVPTLQNI 396 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 246 LGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVT 305 L +P +T +A K + G+ + +Y+ + LQV+ Sbjct: 94 LHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVS 153 Query: 306 EGTIKSGY----KILYEHRDKLVDPQL 328 +I + + K L+ L DP L Sbjct: 154 VYSIGATFLKMVKKLHITELPLADPSL 180 >6F41-V nrPDB Length = 596 Score = 229 bits (584), Expect = 1e-60, Method: Composition-based stats. Identities = 49/279 (17%), Positives = 100/279 (35%), Gaps = 42/279 (15%) Query: 42 DVVCALCGLVLSDKLVDTRSEWRTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGET 101 D+VC CG+V D + + + S + IG G++ Sbjct: 22 DLVCKACGVVSEDNPIVSEVTFGETSAGAAVVQ------------------GSFIGAGQS 63 Query: 102 TDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEK 161 G + ++ ++ + A K+ + A +P+ + D A + YKL Sbjct: 64 HAA--------FGGSSALESREATLNNARRKLRAVSYALHIPEYITDAAFQWYKLALANN 115 Query: 162 TLKGKSMESIMAASILIGCRRAEVARTFKEIQSLIHVKTKEFGKTL-NIMKNILRGKSED 220 ++G+ ++++A+ + + CR+ + + S + V G T ++K Sbjct: 116 FVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVSVYSIGATFLKMVK--------- 166 Query: 221 GFLKIDTDNMSGAQNLTYIPRFCSHLGLP---MQVTTSAEYTAKKCKEIKEIAGKSPITI 277 K+ + A +I F L L ++V A A++ + G+ P I Sbjct: 167 ---KLHITELPLADPSLFIQHFAEKLDLADKKIKVVKDAVKLAQRMSKDWMFEGRRPAGI 223 Query: 278 AVVSIYLNILLFQIPITAAKVGQTLQVTEGTIKSGYKIL 316 A I L + + T ++ V E T++ Sbjct: 224 AGACILLACRMNNLRRTHTEIVAVSHVAEETLQQRLNEF 262 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 70/190 (36%), Gaps = 18/190 (9%) Query: 126 VQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEV 185 + A KI ++ DA +L + + +K+ +G+ I A IL+ CR + Sbjct: 189 LDLADKKIKVVKDAVKLAQRM---SKDW--------MFEGRRPAGIAGACILLACRMNNL 237 Query: 186 ARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIP----- 240 RT EI ++ HV + + LN KN K + + A+ +++ Sbjct: 238 RRTHTEIVAVSHVAEETLQQRLNEFKNTKAAKLSVQKFRENDVEDGEARPPSFVKNRKKE 297 Query: 241 -RFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVG 299 + L TS E K + ++ G+ ++ V YL + ++ Sbjct: 298 RKIKDSLDKEEMFQTS-EEALNKNPILTQVLGEQELSSKEVLFYLKQFSERRARVVERIK 356 Query: 300 QTLQVTEGTI 309 T + I Sbjct: 357 ATNGIDGENI 366 Score = 29.4 bits (64), Expect = 2.3, Method: Composition-based stats. Identities = 17/87 (19%), Positives = 31/87 (35%), Gaps = 4/87 (4%) Query: 246 LGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTLQVT 305 L +P +T +A K + G+ + +Y+ + LQV+ Sbjct: 94 LHIPEYITDAAFQWYKLALANNFVQGRRSQNVIASCLYVACRKEKTHHMLIDFSSRLQVS 153 Query: 306 EGTIKSGY----KILYEHRDKLVDPQL 328 +I + + K L+ L DP L Sbjct: 154 VYSIGATFLKMVKKLHITELPLADPSL 180 >1AIS-B nrPDB Length = 200 Score = 228 bits (582), Expect = 2e-60, Method: Composition-based stats. Identities = 53/201 (26%), Positives = 94/201 (46%), Gaps = 10/201 (4%) Query: 118 VMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASIL 177 V D + + A +++ + +LP+ V++ A Y+ + ++G+S+ES+MAA + Sbjct: 1 VSDAAERNLAFALSELDRITAQLKLPRHVEEEAARLYREAVRKGLIRGRSIESVMAACVY 60 Query: 178 IGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLT 237 CR +V RT EI + V KE G++ + L + F+K Sbjct: 61 AACRLLKVPRTLDEIADIARVDKKEIGRSYRFIARNLNLTPKKLFVK----------PTD 110 Query: 238 YIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAK 297 Y+ +F LGL +V A + + +GKSP + ++Y+ LL T + Sbjct: 111 YVNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQRE 170 Query: 298 VGQTLQVTEGTIKSGYKILYE 318 V + +VTE T+++ YK L E Sbjct: 171 VAEVARVTEVTVRNRYKELVE 191 Score = 43.6 bits (101), Expect = 1e-04, Method: Composition-based stats. Identities = 17/85 (20%), Positives = 30/85 (35%) Query: 133 ITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEVARTFKEI 192 + D L + V+ A E + GKS ++AA++ I RT +E+ Sbjct: 112 VNKFADELGLSEKVRRRAIEILDEAYKRGLTSGKSPAGLVAAALYIASLLEGEKRTQREV 171 Query: 193 QSLIHVKTKEFGKTLNIMKNILRGK 217 + V + L+ K Sbjct: 172 AEVARVTEVTVRNRYKELVEKLKIK 196 >3K1F-M nrPDB Length = 197 Score = 137 bits (345), Expect = 7e-33, Method: Composition-based stats. Identities = 68/68 (100%), Positives = 68/68 (100%) Query: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR Sbjct: 1 MMTRESIDKRAGRRGPNLNIVLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDTR 60 Query: 61 SEWRTFSN 68 SEWRTFSN Sbjct: 61 SEWRTFSN 68 >1RLY-A nrPDB Length = 60 Score = 92.5 bits (228), Expect = 3e-19, Method: Composition-based stats. Identities = 25/51 (49%), Positives = 34/51 (66%), Gaps = 4/51 (7%) Query: 22 LTCPECKVYPPKI-VERFSEGDVVCALCGLVLSDKLVDTRSEWRTFSNDDH 71 +TCP +P I VE + GD++C CGLV+ D+++D SEWRTFSND Sbjct: 13 VTCPN---HPDAILVEDYRAGDMICPECGLVVGDRVIDVGSEWRTFSNDKA 60 >4ROE-A nrPDB Length = 360 Score = 65.9 bits (159), Expect = 2e-11, Method: Composition-based stats. Identities = 25/173 (14%), Positives = 61/173 (35%), Gaps = 9/173 (5%) Query: 120 DKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCHDEKTLKGKSMES---IMAASI 176 ++ Q ++ LC +LP +D A Y+ + ++ ++ ++ + Sbjct: 4 EQVSRSQQRGLRRVRDLCRVLQLPPTFEDTAVAYYQQAYRHSGIRAARLQKKEVLVGCCV 63 Query: 177 LIGCRRAEVARTFKEIQSLIHVKTKEFGKTLNIMKNILRGKSEDG----FLKIDTDNMSG 232 LI CR+ T I +L++ F T + +L +K + Sbjct: 64 LITCRQHNWPLTMGAICTLLYADLDVFSSTYMQIVKLLGLDVPSLCLAELVKTYCSSFKL 123 Query: 233 AQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLN 285 Q +P ++ ++ + + E + G+ P+ + + +L Sbjct: 124 FQASPSVP--AKYVEDKEKMLSRTMQLVELANETWLVTGRHPLPVITAATFLA 174 >1ZP2-A nrPDB Length = 235 Score = 35.9 bits (81), Expect = 0.025, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 25/65 (38%), Gaps = 1/65 (1%) Query: 131 AKITMLCDAAELPKIVKDCAKEAYKL-CHDEKTLKGKSMESIMAASILIGCRRAEVARTF 189 + D L + V A + + KG S+E+++A I + C+ E Sbjct: 33 KVVQTFGDRLRLRQRVLATAIVLLRRYMLKKNEEKGFSLEALVATCIYLSCKVEECPVHI 92 Query: 190 KEIQS 194 + I + Sbjct: 93 RTICN 97 >6E8E-B nrPDB Length = 517 Score = 31.7 bits (70), Expect = 0.47, Method: Composition-based stats. Identities = 30/213 (14%), Positives = 77/213 (36%), Gaps = 22/213 (10%) Query: 138 DAAELPKIVK---DCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAEV------ART 188 LPK + + K + S E + + + ++ Sbjct: 282 YRRVLPKNPDKHLEAGCDLLKQAFARAAI--LSNEKFRGVRLYVSENQLKITANNPEQEE 339 Query: 189 FKEIQSLIHVKTK-EFGKTLNIMKNILRGKSEDGFLKIDTDNMSGAQNLTYIPRFCSHLG 247 +EI + + + E G ++ + ++L + + TD++S Q + +++ Sbjct: 340 AEEILDVTYSGAEMEIGFNVSYVLDVLNALKCENVRMMLTDSVSSVQIEDAASQSAAYVV 399 Query: 248 LPMQVTTSAEYTAKKCKEIKEIAGKSPITIAVVSIYLNILLFQIPITAAKVGQTL----- 302 +PM++ S ++ + G++P+ + I L + + +A + Q+ Sbjct: 400 MPMRLVDSGASGGSWLRQAQLTPGEAPVCAQPLLIPLRLKVSAEEKSALEKAQSALAELG 459 Query: 303 -----QVTEGTIKSGYKILYEHRDKLVDPQLIA 330 TI++ L + +++ P+LI Sbjct: 460 IDFQSDAQHVTIRAVPLPLRQQNLQILIPELIG 492 >4NST-B nrPDB Length = 268 Score = 29.7 bits (65), Expect = 1.7, Method: Composition-based stats. Identities = 19/122 (15%), Positives = 36/122 (29%), Gaps = 7/122 (5%) Query: 173 AASILIGCRRAEVARTFKEI--QSLIHVKTKEFGKTLNIMKNILRGKSEDGFLKIDTDNM 230 A + + + E + K+I + + +FG+ + K + I D + Sbjct: 98 ACCLFLAGKVEETPKKCKDIIKTARSLLNDVQFGQFGDDPKEEVMVLERILLQTIKFD-L 156 Query: 231 SGAQNLTYIPRFCSHLGLPMQVTTSAEYTAKKCKEIKEIAGKS----PITIAVVSIYLNI 286 ++ ++ L A S P IAV +YL Sbjct: 157 QVEHPYQFLLKYAKQLKGDKNKIQKLVQMAWTFVNDSLCTTLSLQWEPEIIAVAVMYLAG 216 Query: 287 LL 288 L Sbjct: 217 RL 218 >5KYJ-A nrPDB Length = 287 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 25/66 (37%), Gaps = 1/66 (1%) Query: 66 FSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNE 125 FS D N +P RV P ++ TRI K +RF + L K + +E Sbjct: 186 FSADRPNVQEPGRVEALQQPYVEALLSYTRI-KRPQDQLRFPRMLMKLVSLRTLSSVHSE 244 Query: 126 VQAAFA 131 A Sbjct: 245 QVFALR 250 >4NQA-B nrPDB Length = 391 Score = 29.7 bits (65), Expect = 1.8, Method: Composition-based stats. Identities = 18/66 (27%), Positives = 25/66 (37%), Gaps = 1/66 (1%) Query: 66 FSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKAQGKNVMDKKDNE 125 FS D N +P RV P ++ TRI K +RF + L K + +E Sbjct: 309 FSADRPNVQEPGRVEALQQPYVEALLSYTRI-KRPQDQLRFPRMLMKLVSLRTLSSVHSE 367 Query: 126 VQAAFA 131 A Sbjct: 368 QVFALR 373 >2F00-A nrPDB Length = 491 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 18/49 (36%), Positives = 22/49 (44%), Gaps = 4/49 (8%) Query: 58 DTRSEWRTFSN----DDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETT 102 D+RS RT D DP+RV E P+L GN+L G G Sbjct: 421 DSRSLCRTIRGRGKIDPILVPDPARVAEMLAPVLTGNDLILVQGAGNIG 469 >6N9E-15 nrPDB Length = 60 Score = 29.7 bits (65), Expect = 2.0, Method: Composition-based stats. Identities = 11/39 (28%), Positives = 16/39 (41%), Gaps = 8/39 (20%) Query: 21 VLTCPECKVYPPKIVERFSEGDVVCALCGLVLSDKLVDT 59 ++ CPECK P VC CG K+++ Sbjct: 30 LVPCPECKAMKPP--------HTVCPECGYYAGRKVLEV 60 >3TTD-A nrPDB Length = 658 Score = 29.4 bits (64), Expect = 2.4, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 12/27 (44%), Gaps = 1/27 (3%) Query: 24 CPEC-KVYPPKIVERFSEGDVVCALCG 49 CP C K Y + RF V C CG Sbjct: 70 CPACDKEYRDPLDRRFHAQPVACPECG 96 >5G4J-A nrPDB Length = 446 Score = 28.6 bits (62), Expect = 3.9, Method: Composition-based stats. Identities = 12/77 (15%), Positives = 26/77 (33%), Gaps = 6/77 (7%) Query: 96 IGKGETTDMRFTKEL------NKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDC 149 IG TT + N G V V + ++ A +L K ++ Sbjct: 289 IGAVVTTAELLDEFGRHNMFFNTFAGNPVSSAAGLAVLRYMDQEDLMAKADQLGKYIRKR 348 Query: 150 AKEAYKLCHDEKTLKGK 166 + + + +++G+ Sbjct: 349 LENIAQRSGNVGSVRGR 365 >4R12-A nrPDB Length = 593 Score = 28.2 bits (61), Expect = 5.1, Method: Composition-based stats. Identities = 12/50 (24%), Positives = 21/50 (42%) Query: 64 RTFSNDDHNGDDPSRVGEASNPLLDGNNLSTRIGKGETTDMRFTKELNKA 113 +T+++D DP R A ++ +ST I + + K L K Sbjct: 291 KTYNSDKSKCIDPPRADLAFQTQINFTKISTIIELNQIGRAQLDKNLGKY 340 >6EL3-D nrPDB Length = 381 Score = 28.2 bits (61), Expect = 6.0, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 30/92 (32%), Gaps = 14/92 (15%) Query: 99 GETTDMRFTKELNKAQGKNVMDKKDNEVQAAFAKITMLCDAAELPKIVKDCAKEAYKLCH 158 G D FT+++ + Q +N +++ + KI + + P ++ Y L Sbjct: 151 GPRHDPPFTEDMPRLQIQNFYYTQEDILFEEIKKIETVTWSIHRPNMIF--GFSPYSL-- 206 Query: 159 DEKTLKGKSMESIMAASILIG-CRRAEVARTF 189 M + + C+ F Sbjct: 207 ---------MNIVGTLCVYAAICKHEGSPLLF 229 >1KXU-A nrPDB Length = 333 Score = 27.4 bits (59), Expect = 9.7, Method: Composition-based stats. Identities = 8/43 (18%), Positives = 16/43 (37%) Query: 142 LPKIVKDCAKEAYKLCHDEKTLKGKSMESIMAASILIGCRRAE 184 +P+ V A +K + ++ IM + C+ E Sbjct: 85 MPRSVVGTACMYFKRFYLNNSVMEYHPRIIMLTCAFLACKVDE 127 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.311 0.126 0.321 Lambda K H 0.267 0.0386 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,357,857 Number of Sequences: 36641 Number of extensions: 412879 Number of successful extensions: 1191 Number of sequences better than 10.0: 22 Number of HSP's better than 10.0 without gapping: 24 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 1124 Number of HSP's gapped (non-prelim): 49 length of query: 345 length of database: 10,336,785 effective HSP length: 98 effective length of query: 247 effective length of database: 6,745,967 effective search space: 1666253849 effective search space used: 1666253849 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.4 bits) S2: 59 (27.4 bits)