BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P28861 (248 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1FDR-A nrPDB 513 e-146 3FPK-A nrPDB 473 e-134 2QDX-A nrPDB 147 5e-36 4FK8-A nrPDB 147 6e-36 5THX-A nrPDB 140 4e-34 4B4D-A nrPDB 137 3e-33 1A8P-A nrPDB 137 4e-33 2VNH-A nrPDB 129 1e-30 5UFA-A nrPDB 122 1e-28 1KRH-A nrPDB 63 1e-10 3W2G-A nrPDB 52 2e-07 2EIX-A nrPDB 50 7e-07 1UMK-A nrPDB 49 2e-06 5OGX-A nrPDB 48 4e-06 3OZU-A nrPDB 43 1e-04 4WQM-A nrPDB 41 5e-04 2B5O-A nrPDB 39 0.001 5A60-A nrPDB 31 0.46 2R6H-A nrPDB 30 1.2 4GIR-A nrPDB 30 1.2 3CFI-B nrPDB 29 1.6 2YN1-A nrPDB 29 2.2 1TLL-A nrPDB 28 3.5 5WU7-A nrPDB 27 9.1 >1FDR-A nrPDB Length = 248 Score = 513 bits (1320), Expect = e-146, Method: Compositional matrix adjust. Identities = 247/248 (99%), Positives = 248/248 (100%) Query: 1 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN Sbjct: 1 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP Sbjct: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS 180 YLSIL+LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS Sbjct: 121 YLSILRLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS 180 Query: 181 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG Sbjct: 181 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 Query: 241 HMTAEHYW 248 HMTAEHYW Sbjct: 241 HMTAEHYW 248 >3FPK-A nrPDB Length = 251 Score = 473 bits (1216), Expect = e-134, Method: Compositional matrix adjust. Identities = 223/248 (89%), Positives = 237/248 (95%) Query: 1 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 MADWVTGKVTKVQNWTDALFSLTVHAP+ PFTAGQFTKLGLEIDGERVQRAYSYVN+PDN Sbjct: 4 MADWVTGKVTKVQNWTDALFSLTVHAPINPFTAGQFTKLGLEIDGERVQRAYSYVNAPDN 63 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 P+LEFYLVTVP GKLSPRLAALKPGDEVQVVS+A+GFFVLDEVP CETLWMLATGTAIGP Sbjct: 64 PNLEFYLVTVPQGKLSPRLAALKPGDEVQVVSDASGFFVLDEVPDCETLWMLATGTAIGP 123 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS 180 YLSILQ G+D+ RFKNLVLVHAAR+AADLSYLPLM EL++RYEGKLRIQTVVSRE GS Sbjct: 124 YLSILQYGQDVARFKNLVLVHAARFAADLSYLPLMLELQQRYEGKLRIQTVVSRENVPGS 183 Query: 181 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 LTGR+PALIE+GELE +GLPM+KETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG Sbjct: 184 LTGRVPALIENGELEKAVGLPMDKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 243 Query: 241 HMTAEHYW 248 HMTAEHYW Sbjct: 244 HMTAEHYW 251 >2QDX-A nrPDB Length = 257 Score = 147 bits (370), Expect = 5e-36, Method: Compositional matrix adjust. Identities = 86/233 (36%), Positives = 132/233 (56%), Gaps = 11/233 (4%) Query: 2 ADWVTGKVTKVQNWTDALFSL-TVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 ++ T +V V +W D LFS T P L F GQF +GLE+DG + RAYS + Sbjct: 1 SNLYTERVLSVHHWNDTLFSFKTTRNPGLRFKTGQFVMIGLEVDGRPLMRAYSIASPNYE 60 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 LEF+ + VPDG L+ RL LK GDE+ V + G V D++ + L++L+TGT + P Sbjct: 61 EHLEFFSIKVPDGPLTSRLQHLKEGDELMVSRKPTGTLVHDDLLPGKHLYLLSTGTGMAP 120 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQEL--EKRYEG-----KLRIQTVVS 173 +LS++Q + +R++ ++LVH R+ ++L+Y + ++ E Y G KL +V+ Sbjct: 121 FLSVIQDPETYERYEKVILVHGVRWVSELAYADFITKVLPEHEYFGDQVKEKLIYYPLVT 180 Query: 174 RETAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLL 225 RE GR L+ SG+L IGL PMN + M+CG+P M+ +T +L Sbjct: 181 REPFRNQ--GRQTDLMRSGKLFEDIGLPPMNPQDDRAMICGSPSMLEETSAVL 231 >4FK8-A nrPDB Length = 271 Score = 147 bits (370), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 94/254 (37%), Positives = 135/254 (53%), Gaps = 12/254 (4%) Query: 1 MADWVTGKVTKVQNWTDALFSLTV-HAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPD 59 M+ + T V V +WTD LFS T L F G+FT +GLE+DG+ + RAYS V+ Sbjct: 16 MSKFDTATVLSVHHWTDTLFSFTCTRDQALRFNNGEFTMVGLEVDGKPLTRAYSIVSPNY 75 Query: 60 NPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIG 119 LEF+ + V +G L+ RL LK GD V + + G V D + +TLWML+TGT + Sbjct: 76 EEHLEFFSIKVQNGPLTSRLQHLKVGDPVLIGKKPTGTLVADNLLPGKTLWMLSTGTGLA 135 Query: 120 PYLSILQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVV 172 P++SI++ +RF +VL H R +L+Y LP + L KL V Sbjct: 136 PFMSIIRDPDIYERFDKVVLTHTCRLKGELAYMDYIKHDLPGHEYLGDVIREKLVYYPTV 195 Query: 173 SRETAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLLKETRQM 231 +RE GRI LI SG+L + + + P + E VMLCG+ M++DT +LLK+ + Sbjct: 196 TREEFENE--GRITDLIASGKLFTDLDMPPFSPEQDRVMLCGSTAMLKDTTELLKKA-GL 252 Query: 232 TKHLRRRPGHMTAE 245 + PGH E Sbjct: 253 VEGKNSAPGHYVIE 266 >5THX-A nrPDB Length = 266 Score = 140 bits (354), Expect = 4e-34, Method: Compositional matrix adjust. Identities = 88/231 (38%), Positives = 130/231 (56%), Gaps = 11/231 (4%) Query: 6 TGKVTKVQNWTDALFSLT-VHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLE 64 T KV V +WTDA F+ T + L F GQF +GL DG+ + RAYS ++ LE Sbjct: 14 TQKVLSVHHWTDAYFTFTCIRDESLRFENGQFVMVGLMADGKPLMRAYSVASANWEEHLE 73 Query: 65 FYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSI 124 F+ + V DG L+ RL LK GDEV + + G V ++ + L++L+TGT I P+LSI Sbjct: 74 FFSIKVQDGPLTSRLQHLKVGDEVLISKKPTGTLVACDLNPGKHLYLLSTGTGIAPFLSI 133 Query: 125 LQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVVSRETA 177 + + ++F+ ++LVH RY DL+Y LP + L + KL +VSRE Sbjct: 134 TKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSREEF 193 Query: 178 AGSLTGRIPALIESGELESTIGLP-MNKETSHVMLCGNPQMVRDTQQLLKE 227 GR+ L+ SG+L IGLP +N + MLCG+P M++DT ++L + Sbjct: 194 EHR--GRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDD 242 >4B4D-A nrPDB Length = 262 Score = 137 bits (346), Expect = 3e-33, Method: Compositional matrix adjust. Identities = 84/246 (34%), Positives = 128/246 (52%), Gaps = 11/246 (4%) Query: 9 VTKVQNWTDALFSLTVHAPV-LPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYL 67 V +V++WTDA FS T F GQF +GLE + + RAYS ++ LEF+ Sbjct: 13 VLEVRHWTDAYFSFTTTRDAGFRFENGQFVMIGLETETRPLLRAYSIASANWEEHLEFFS 72 Query: 68 VTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQL 127 + VPDG L+ RL ++PGD+V V + G ++ ++ L++L TGT + P+LSI++ Sbjct: 73 IKVPDGPLTSRLQHIQPGDKVLVGKKPTGTLLISDLHPGRNLYLLGTGTGLAPWLSIIKD 132 Query: 128 GKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVVSRETAAGS 180 + +RF ++L R+ DL+Y LP + L KL V+RET A Sbjct: 133 PETYERFDKVILTQGVRFVQDLAYRDYFERELPQHEFLGDLLREKLLYYPAVTRETFANQ 192 Query: 181 LTGRIPALIESGELESTIGLP-MNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRP 239 GR+ L+ G ++ T+GLP ++ M+CG+PQM+ D + LL T P Sbjct: 193 --GRLTELMADGRMQQTLGLPTLDPANDRFMICGSPQMLADLRSLLDSRGFQTSPRIGTP 250 Query: 240 GHMTAE 245 GH E Sbjct: 251 GHYVFE 256 >1A8P-A nrPDB Length = 258 Score = 137 bits (345), Expect = 4e-33, Method: Compositional matrix adjust. Identities = 81/234 (34%), Positives = 129/234 (55%), Gaps = 11/234 (4%) Query: 1 MADWVTGKVTKVQNWTDALFSL-TVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPD 59 M++ +V V +W D LFS T P L F GQF +GLE+DG + RAYS + Sbjct: 1 MSNLNVERVLSVHHWNDTLFSFKTTRNPSLRFENGQFVMIGLEVDGRPLMRAYSIASPNY 60 Query: 60 NPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIG 119 LEF+ + V +G L+ RL LK GDE+ V + G V ++ + L+ML+TGT + Sbjct: 61 EEHLEFFSIKVQNGPLTSRLQHLKEGDELMVSRKPTGTLVTSDLLPGKHLYMLSTGTGLA 120 Query: 120 PYLSILQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVV 172 P++S++Q + +RF+ +VL+H R +L+Y LP + + + KL V Sbjct: 121 PFMSLIQDPEVYERFEKVVLIHGVRQVNELAYQQFITEHLPQSEYFGEAVKEKLIYYPTV 180 Query: 173 SRETAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLL 225 +RE+ GR+ L+ SG+L IGL P+N + M+CG+P M+ ++ ++L Sbjct: 181 TRESFHNQ--GRLTDLMRSGKLFEDIGLPPINPQDDRAMICGSPSMLDESCEVL 232 >2VNH-A nrPDB Length = 272 Score = 129 bits (324), Expect = 1e-30, Method: Compositional matrix adjust. Identities = 81/231 (35%), Positives = 129/231 (55%), Gaps = 18/231 (7%) Query: 9 VTKVQNWTDALFSLTVHAP-VLPFTAGQFTKLGL-EIDGERVQRAYSYVNSPDNPDLEFY 66 VT V++WTD LFS V P L F +G+F +GL + +G+ + RAYS + + +LEFY Sbjct: 21 VTSVRHWTDTLFSFRVTRPQTLRFRSGEFVMIGLLDDNGKPIMRAYSIASPAWDEELEFY 80 Query: 67 LVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQ 126 + VPDG L+ RL +K G+++ + + G V+D + + LW LATGT I P+ S+++ Sbjct: 81 SIKVPDGPLTSRLQHIKVGEQIILRPKPVGTLVIDALLPGKRLWFLATGTGIAPFASLMR 140 Query: 127 LGKDLDRFKNLVLVHAARYAADLSY----------LPLMQELEKRYEGKLRIQTVVSRET 176 + ++F ++++HA R A+L Y PL+ EL EGKL+ +RE Sbjct: 141 EPEAYEKFDEVIMMHACRTVAELEYGRQLVEALQEDPLIGEL---VEGKLKYYPTTTREE 197 Query: 177 AAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLLK 226 GRI + SG++ +G+ PMN ET M+CG+ D ++L+ Sbjct: 198 F--HHMGRITDNLASGKVFEDLGIAPMNPETDRAMVCGSLAFNVDVMKVLE 246 >5UFA-A nrPDB Length = 267 Score = 122 bits (306), Expect = 1e-28, Method: Compositional matrix adjust. Identities = 76/252 (30%), Positives = 126/252 (50%), Gaps = 8/252 (3%) Query: 2 ADWVTGKVTKVQNWTDALFSLTVHAP-VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 A + K+ V++ T L + + P F AGQF++LG + RAYS V++ Sbjct: 15 AKFTEEKILWVKHHTPKLITFAISRPESYRFKAGQFSRLGFYEGKGFIWRAYSVVSAEYA 74 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 LE++ V + DG +S A ++ GD + + A GF + + P + L ML TG+ I P Sbjct: 75 DTLEYFAVLIQDGPMSALFAKMQQGDTILLDKNATGFLLPERFPDGKDLVMLCTGSGIAP 134 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKR-----YEGKLRIQTVVSRE 175 +LSIL+ + RF + L+H+ + +L + + L + Y R V +R Sbjct: 135 FLSILEQPEIRQRFDTVNLIHSVSFPEELIFNDRLAALSEHPLVGEYGHSFRFVPVTTRA 194 Query: 176 TAAGSLTG-RIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKH 234 L+G RIP L+++ +E + + E++ M+CGNP+MV+DT Q L + H Sbjct: 195 ANPSGLSGKRIPELLKNNSIEQALHTKLTPESTRFMICGNPEMVKDTFQTLLDM-GYAMH 253 Query: 235 LRRRPGHMTAEH 246 R PG + E+ Sbjct: 254 RNRIPGQIMMEN 265 >1KRH-A nrPDB Length = 338 Score = 63.2 bits (152), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 51/187 (27%), Positives = 86/187 (45%), Gaps = 13/187 (6%) Query: 7 GKVTKVQNWTDALFSLTVH----APVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD 62 G + +V+N +D+ + + P + F AGQ+ + L G R+YS+ + P N Sbjct: 111 GTLARVENLSDSTITFDIQLDDGQPDIHFLAGQYVNVTLP--GTTETRSYSFSSQPGNRL 168 Query: 63 LEFYLVTVPDGKLSPRLAA-LKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPY 121 F + VP GK+S L+ K GD++ F++ D + MLA GT I P+ Sbjct: 169 TGFVVRNVPQGKMSEYLSVQAKAGDKMSFTGPFGSFYLRDVK---RPVLMLAGGTGIAPF 225 Query: 122 LSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKR---YEGKLRIQTVVSRETAA 178 LS+LQ+ + + LV DL L + L+++ +E + + S+ Sbjct: 226 LSMLQVLEQKGSEHPVRLVFGVTQDCDLVALEQLDALQQKLPWFEYRTVVAHAESQHERK 285 Query: 179 GSLTGRI 185 G +TG I Sbjct: 286 GYVTGHI 292 >3W2G-A nrPDB Length = 271 Score = 52.0 bits (123), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 53/225 (23%), Positives = 94/225 (41%), Gaps = 30/225 (13%) Query: 20 FSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTV--------- 70 F+L +L GQ L IDG V R Y+ V+S D+ ++ V Sbjct: 32 FALPSPEHILGLPVGQHIYLSARIDGNLVIRPYTPVSSDDDKGFVDLVIKVYFKDTHPKF 91 Query: 71 -PDGKLSPRLAALKPGDEVQ-------VVSEAAGFFVLDE-------VPHCETLWMLATG 115 GK+S L ++K GD ++ +V + G F + + +++ M+A G Sbjct: 92 PAGGKMSQYLESMKIGDTIEFRGPNGLLVYQGKGKFAIRPDKKSSPVIKTVKSVGMIAGG 151 Query: 116 TAIGPYLSILQ-LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSR 174 T I P L +++ + KD D L+ A + D+ P ++EL + + ++ V R Sbjct: 152 TGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNEHSARFKLWYTVDR 211 Query: 175 ETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVR 219 A + + + LP +E V++CG P M++ Sbjct: 212 APEAWDYSQ---GFVNEEMIRDH--LPPPEEEPLVLMCGPPPMIQ 251 >2EIX-A nrPDB Length = 243 Score = 50.4 bits (119), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 52/221 (23%), Positives = 95/221 (42%), Gaps = 14/221 (6%) Query: 11 KVQNWTDALFSLTVHAP--VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD-LEFYL 67 ++ N LF +H P V+ GQ + +DG+ + R Y+ V+S D + + Sbjct: 20 QIINHNTRLFRFNLHHPEDVVGLPIGQHMSVKATVDGKEIYRPYTPVSSDDEKGYFDLII 79 Query: 68 VTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPH-CETLWMLATGTAIGPYLSILQ 126 G++S + L PGD +QV F D P+ + + M+A GT I P L + + Sbjct: 80 KVYEKGQMSQYIDHLNPGDFLQVRGPKGQF---DYKPNMVKEMGMIAGGTGITPMLQVAR 136 Query: 127 LGKDLDRFKNLV-LVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRI 185 + K ++ L+ A D+ + ++ K+Y ++ V++ A TG + Sbjct: 137 AIIKNPKEKTIINLIFANVNEDDILLRTELDDMAKKYS-NFKVYYVLNNPPAG--WTGGV 193 Query: 186 PALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLK 226 + + ++ P VM+CG P M + Q L+ Sbjct: 194 -GFVSADMIKQHFSPP--SSDIKVMMCGPPMMNKAMQGHLE 231 >1UMK-A nrPDB Length = 275 Score = 48.9 bits (115), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 50/225 (22%), Positives = 94/225 (41%), Gaps = 30/225 (13%) Query: 20 FSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTV--------- 70 F+L +L GQ L IDG V R Y+ ++S D+ ++ V Sbjct: 36 FALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLVIKVYFKDTHPKF 95 Query: 71 -PDGKLSPRLAALKPGDEVQ-------VVSEAAGFFVLDE-------VPHCETLWMLATG 115 GK+S L +++ GD ++ +V + G F + + +++ M+A G Sbjct: 96 PAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPIIRTVKSVGMIAGG 155 Query: 116 TAIGPYLSILQ-LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSR 174 T I P L +++ + KD D L+ A + D+ P ++EL ++ + ++ + R Sbjct: 156 TGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKHSARFKLWYTLDR 215 Query: 175 ETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVR 219 A + + LP +E V++CG P M++ Sbjct: 216 APEAWDYGQ---GFVNEEMIRDH--LPPPEEEPLVLMCGPPPMIQ 255 >5OGX-A nrPDB Length = 336 Score = 48.1 bits (113), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 61/219 (27%), Positives = 90/219 (41%), Gaps = 27/219 (12%) Query: 29 LPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD-LEFYLVTVP-----DGKLSPRLAAL 82 L F AGQ+ +L + G +R YS N+ D LE ++ VP DG L LAA Sbjct: 128 LAFEAGQYVEL--VVPGSGARRQYSLANTADEDKVLELHVRRVPGGVATDGWLFDGLAA- 184 Query: 83 KPGDEVQVVSEAAGFFVL--DEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLV 140 GD V+ F + DE + ++ GT + P + I + + ++L Sbjct: 185 --GDRVEATGPLGDFHLPPPDE-DDGGPMVLIGGGTGLAPLVGIARTALARHPSREVLLY 241 Query: 141 HAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIP--ALIESGELESTI 198 H R AADL L E+ + + G R V+S E + G P A +E Sbjct: 242 HGVRGAADLYDLGRFAEIAEEHPG-FRFVPVLSDEPDP-AYRGGFPTDAFVED------- 292 Query: 199 GLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRR 237 +P + S LCG P MV + K R + + R Sbjct: 293 -VPSGRGWSG-WLCGPPAMVEAGVKAFKRRRMSPRRIHR 329 >3OZU-A nrPDB Length = 403 Score = 43.1 bits (100), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 55/239 (23%), Positives = 106/239 (44%), Gaps = 26/239 (10%) Query: 4 WVTGKVTKVQNWTDALFSLTVH----APVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPD 59 W T + + + +D + S + PV+ F GQ+T + +++ +Q+ Y S D Sbjct: 154 WRTFVIREKRPESDVITSFILEPADGGPVVNFEPGQYTSVAIDVPALGLQQIRQYSLS-D 212 Query: 60 NPDLEFYLVTV--------PDGKLSPRL-AALKPGDEVQVVSEAAGFFVLDEVPHCETLW 110 P+ Y ++V P G +S L + GD+V++ + F + +V + Sbjct: 213 MPNGRSYRISVKREGGGPQPPGYVSNLLHDHVNVGDQVKLAAPYGSFHI--DVDAKTPIV 270 Query: 111 MLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQT 170 +++ G + P +S+L++ + +V VH AR +A + ++E K YE L + Sbjct: 271 LISGGVGLTPMVSMLKVALQAPP-RQVVFVHGARNSAVHAMRDRLREAAKTYE-NLDL-F 327 Query: 171 VVSRETAAGSLTGR---IPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLK 226 V + + GR P L++ ++E +I LP + +CG +R LK Sbjct: 328 VFYDQPLPEDVQGRDYDYPGLVDVKQIEKSILLP----DADYYICGPIPFMRMQHDALK 382 >4WQM-A nrPDB Length = 326 Score = 40.8 bits (94), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 51/219 (23%), Positives = 95/219 (43%), Gaps = 16/219 (7%) Query: 8 KVTKVQNWTDALFSLTVHAP-VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFY 66 +V + +D +F L + A + F+ GQ+ + + E RAYS N D L Sbjct: 106 RVVSKRFLSDEMFELRLEAEQKVVFSPGQYFMVDVP---ELGTRAYSAANPVDGNTLTLI 162 Query: 67 LVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQ 126 + VP+GK+S LA E + G VL ++++ +A G+ I P +S++ Sbjct: 163 VKAVPNGKVSCALA--NETIETLQLDGPYGLSVLKTADETQSVF-IAGGSGIAPMVSMVN 219 Query: 127 LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIP 186 K + + + +R A+L + ++ + + + + V + + TG + Sbjct: 220 TLIAQGYEKPITVFYGSRLEAELEAAETLFGWKENLK-LINVSSSVVGNSESSYPTGYVH 278 Query: 187 ALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLL 225 +I +E +G + LCG PQM+ Q+LL Sbjct: 279 EIIPE-YMEGLLG-------AEFYLCGPPQMINSVQKLL 309 >2B5O-A nrPDB Length = 402 Score = 39.3 bits (90), Expect = 0.001, Method: Compositional matrix adjust. Identities = 41/151 (27%), Positives = 65/151 (43%), Gaps = 15/151 (9%) Query: 108 TLWMLATGTAIGPYLSIL-QLGKDLD---RFKNLV-LVHAARYAADLSYLPLMQELEKRY 162 T+ MLATGT I P+ + L ++ K+ +FK L+ Y A++ Y +++ Sbjct: 252 TVVMLATGTGIAPFRAFLWRMFKEQHEDYKFKGKAWLIFGVPYTANILYKDDFEKMAAEN 311 Query: 163 EGKLRIQTVVSRE--TAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQM--- 217 R+ +SRE TA G G++ E + + K +HV +CG M Sbjct: 312 PDNFRLTYAISREQKTADG---GKVYVQSRVSEYADELFEMIQKPNTHVYMCGLKGMQPP 368 Query: 218 VRDTQQLLKETRQMTKHLRRRPGHMTAEHYW 248 + +T E R + RR M EH W Sbjct: 369 IDETFTAEAEKRGLNWEEMRR--SMKKEHRW 397 >5A60-A nrPDB Length = 435 Score = 31.2 bits (69), Expect = 0.46, Method: Compositional matrix adjust. Identities = 20/59 (33%), Positives = 30/59 (50%), Gaps = 3/59 (5%) Query: 108 TLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKL 166 T W+++ A P+L GK D FK +H +R+AA+L + Q L RY +L Sbjct: 316 TEWLVSK--AWQPFLDAKAQGKISDSFKRFADIHLSRHAAELKSV-FCQPLGDRYHDQL 371 >2R6H-A nrPDB Length = 290 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 26/114 (22%), Positives = 49/114 (42%), Gaps = 5/114 (4%) Query: 73 GKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLS-ILQLGKDL 131 G S + +LKPGD+V + F + D E L+ + G + P + IL L + L Sbjct: 126 GISSSYIFSLKPGDKVMMSGPYGDFHIQDT--DAEMLY-IGGGAGMAPLRAQILHLFRTL 182 Query: 132 DRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRI 185 + + + AR ++ Y +E+E+ + + +S + TG + Sbjct: 183 KTGRKVSYWYGARSKNEIFYEEDFREIEREFP-NFKFHIALSDPQPEDNWTGYV 235 >4GIR-A nrPDB Length = 422 Score = 29.6 bits (65), Expect = 1.2, Method: Compositional matrix adjust. Identities = 36/157 (22%), Positives = 66/157 (42%), Gaps = 32/157 (20%) Query: 112 LATGTAIGPYLSILQLGKDLDRFKNL---VLVHAA-------------------RYAADL 149 LA T + YL L +GKD + ++L ++V+A A + Sbjct: 68 LAVKTMVDEYLKPLLIGKDANNIEDLWQMMMVNAYWRNGPVINNAISGVDMALWDIKAKI 127 Query: 150 SYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESG------ELESTIGLPMN 203 + +PL Q + +++ T + +T G L ++ +E G +L G+P N Sbjct: 128 ANMPLHQLFGGKSRDAIQVYTHATSDTMEG-LYEQVDKYLEQGYQHIRCQLGFYGGVPEN 186 Query: 204 KETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 +T+ G+ D Q ++ T +M K+LR + G Sbjct: 187 IQTAQNPTQGS---YYDQDQYIENTVEMFKNLREKYG 220 >3CFI-B nrPDB Length = 164 Score = 29.3 bits (64), Expect = 1.6, Method: Compositional matrix adjust. Identities = 19/61 (31%), Positives = 26/61 (42%), Gaps = 12/61 (19%) Query: 11 KVQNWTDALFS----------LTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 K+ +W D L L H P F G+ TK+G I ER++R + PD Sbjct: 43 KLLHWADYLLDSDNKGIMFARLGWHNPQQQFPRGEVTKVGYRIKDERLERV--WWRYPDT 100 Query: 61 P 61 P Sbjct: 101 P 101 >2YN1-A nrPDB Length = 106 Score = 28.9 bits (63), Expect = 2.2, Method: Compositional matrix adjust. Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 5/50 (10%) Query: 153 PLMQELEKRYEGKLRIQTV---VSRETAAGSLTGRIPALI--ESGELEST 197 P++ E+ + YEGKL++ V + ETAA IP L+ ++GE+ +T Sbjct: 39 PILDEIAEEYEGKLKVAKVNIDENPETAAKYGIRGIPTLMLFKNGEVAAT 88 >1TLL-A nrPDB Length = 688 Score = 28.1 bits (61), Expect = 3.5, Method: Compositional matrix adjust. Identities = 45/204 (22%), Positives = 80/204 (39%), Gaps = 26/204 (12%) Query: 50 RAYSYVNSPDNPDLEFYLVT-------------VPDGKLSPRLAALKPGDEVQVVSEAAG 96 R YS +SPD E +L V G S L ++ D V A Sbjct: 432 RYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSWLNRIQADDVVPCFVRGAP 491 Query: 97 FFVLDEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNL-----VLVHAARYAADLSY 151 F L P + ++ GT I P+ S Q + + K + VLV R + + + Sbjct: 492 SFHLPRNPQVPCI-LVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCR-QSKIDH 549 Query: 152 LPLMQELEKRYEGKLR-IQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVM 210 + + L+ + +G R + T SRE + + +L ++ + ++ H+ Sbjct: 550 IYREETLQAKNKGVFRELYTAYSREP---DRPKKYVQDVLQEQLAESVYRALKEQGGHIY 606 Query: 211 LCGNPQMVRDTQQLLKETRQMTKH 234 +CG+ M D + ++ R MT+ Sbjct: 607 VCGDVTMAADVLKAIQ--RIMTQQ 628 >5WU7-A nrPDB Length = 568 Score = 26.9 bits (58), Expect = 9.1, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 17/24 (70%) Query: 150 SYLPLMQELEKRYEGKLRIQTVVS 173 SY+PL+ ELEK E +R + V+S Sbjct: 36 SYIPLLMELEKLKERGVRFELVIS 59 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1FDR-A nrPDB 354 2e-98 3FPK-A nrPDB 348 1e-96 5THX-A nrPDB 301 2e-82 1A8P-A nrPDB 298 2e-81 2QDX-A nrPDB 297 3e-81 4FK8-A nrPDB 296 8e-81 4B4D-A nrPDB 286 6e-78 5UFA-A nrPDB 265 1e-71 2VNH-A nrPDB 258 2e-69 2EIX-A nrPDB 196 9e-51 3W2G-A nrPDB 186 1e-47 3OZU-A nrPDB 185 2e-47 1KRH-A nrPDB 184 3e-47 4WQM-A nrPDB 183 9e-47 1UMK-A nrPDB 176 9e-45 5OGX-A nrPDB 173 6e-44 2B5O-A nrPDB 141 2e-34 Sequences not found previously or not previously below threshold: 1GVH-A nrPDB 105 2e-23 4U9U-A nrPDB 104 4e-23 4P6V-F nrPDB 104 4e-23 2R6H-A nrPDB 100 7e-22 6O0A-A nrPDB 85 4e-17 4G1B-A nrPDB 83 9e-17 4EH1-A nrPDB 82 2e-16 1QFJ-A nrPDB 81 4e-16 1TLL-A nrPDB 72 2e-13 4YRY-A nrPDB 65 3e-11 5KSW-B nrPDB 62 2e-10 2PIA-A nrPDB 60 8e-10 2BN4-A nrPDB 56 1e-08 6EFV-A nrPDB 52 2e-07 3ES9-A nrPDB 52 2e-07 6J79-A nrPDB 51 5e-07 5GXU-A nrPDB 48 5e-06 3FJO-A nrPDB 47 6e-06 3QFR-A nrPDB 47 6e-06 5O0X-A nrPDB 46 1e-05 1EP2-B nrPDB 46 2e-05 5JCA-S nrPDB 38 0.005 3NAW-A nrPDB 32 0.24 4M4Z-A nrPDB 29 1.5 1V5X-A nrPDB 29 2.1 1TMX-A nrPDB 28 3.5 4C7Y-A nrPDB 27 5.5 >1FDR-A nrPDB Length = 248 Score = 354 bits (909), Expect = 2e-98, Method: Composition-based stats. Identities = 247/248 (99%), Positives = 248/248 (100%) Query: 1 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN Sbjct: 1 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP Sbjct: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS 180 YLSIL+LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS Sbjct: 121 YLSILRLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS 180 Query: 181 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG Sbjct: 181 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 Query: 241 HMTAEHYW 248 HMTAEHYW Sbjct: 241 HMTAEHYW 248 >3FPK-A nrPDB Length = 251 Score = 348 bits (893), Expect = 1e-96, Method: Composition-based stats. Identities = 223/248 (89%), Positives = 237/248 (95%) Query: 1 MADWVTGKVTKVQNWTDALFSLTVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 MADWVTGKVTKVQNWTDALFSLTVHAP+ PFTAGQFTKLGLEIDGERVQRAYSYVN+PDN Sbjct: 4 MADWVTGKVTKVQNWTDALFSLTVHAPINPFTAGQFTKLGLEIDGERVQRAYSYVNAPDN 63 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 P+LEFYLVTVP GKLSPRLAALKPGDEVQVVS+A+GFFVLDEVP CETLWMLATGTAIGP Sbjct: 64 PNLEFYLVTVPQGKLSPRLAALKPGDEVQVVSDASGFFVLDEVPDCETLWMLATGTAIGP 123 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGS 180 YLSILQ G+D+ RFKNLVLVHAAR+AADLSYLPLM EL++RYEGKLRIQTVVSRE GS Sbjct: 124 YLSILQYGQDVARFKNLVLVHAARFAADLSYLPLMLELQQRYEGKLRIQTVVSRENVPGS 183 Query: 181 LTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 240 LTGR+PALIE+GELE +GLPM+KETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG Sbjct: 184 LTGRVPALIENGELEKAVGLPMDKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRRRPG 243 Query: 241 HMTAEHYW 248 HMTAEHYW Sbjct: 244 HMTAEHYW 251 >5THX-A nrPDB Length = 266 Score = 301 bits (770), Expect = 2e-82, Method: Composition-based stats. Identities = 90/251 (35%), Positives = 133/251 (52%), Gaps = 11/251 (4%) Query: 4 WVTGKVTKVQNWTDALFSLT-VHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD 62 + T KV V +WTDA F+ T + L F GQF +GL DG+ + RAYS ++ Sbjct: 12 FNTQKVLSVHHWTDAYFTFTCIRDESLRFENGQFVMVGLMADGKPLMRAYSVASANWEEH 71 Query: 63 LEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYL 122 LEF+ + V DG L+ RL LK GDEV + + G V ++ + L++L+TGT I P+L Sbjct: 72 LEFFSIKVQDGPLTSRLQHLKVGDEVLISKKPTGTLVACDLNPGKHLYLLSTGTGIAPFL 131 Query: 123 SILQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVVSRE 175 SI + + ++F+ ++LVH RY DL+Y LP + L + KL +VSRE Sbjct: 132 SITKDPEIYEQFEKIILVHGVRYKKDLAYYDRFTKELPEHEYLGDLVKEKLIYYPIVSRE 191 Query: 176 TAAGSLTGRIPALIESGELESTIGLP-MNKETSHVMLCGNPQMVRDTQQLLKETRQMTKH 234 GR+ L+ SG+L IGLP +N + MLCG+P M++DT ++L + Sbjct: 192 EFE--HRGRLTDLMVSGKLFEDIGLPKINPQDDRAMLCGSPAMLKDTCKVLDDFGLTVSP 249 Query: 235 LRRRPGHMTAE 245 G E Sbjct: 250 KTGVRGDYLIE 260 >1A8P-A nrPDB Length = 258 Score = 298 bits (762), Expect = 2e-81, Method: Composition-based stats. Identities = 84/254 (33%), Positives = 132/254 (51%), Gaps = 11/254 (4%) Query: 1 MADWVTGKVTKVQNWTDALFSL-TVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPD 59 M++ +V V +W D LFS T P L F GQF +GLE+DG + RAYS + Sbjct: 1 MSNLNVERVLSVHHWNDTLFSFKTTRNPSLRFENGQFVMIGLEVDGRPLMRAYSIASPNY 60 Query: 60 NPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIG 119 LEF+ + V +G L+ RL LK GDE+ V + G V ++ + L+ML+TGT + Sbjct: 61 EEHLEFFSIKVQNGPLTSRLQHLKEGDELMVSRKPTGTLVTSDLLPGKHLYMLSTGTGLA 120 Query: 120 PYLSILQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVV 172 P++S++Q + +RF+ +VL+H R +L+Y LP + + + KL V Sbjct: 121 PFMSLIQDPEVYERFEKVVLIHGVRQVNELAYQQFITEHLPQSEYFGEAVKEKLIYYPTV 180 Query: 173 SRETAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLLKETRQM 231 +RE+ GR+ L+ SG+L IGL P+N + M+CG+P M+ ++ ++L Sbjct: 181 TRESFHNQ--GRLTDLMRSGKLFEDIGLPPINPQDDRAMICGSPSMLDESCEVLDGFGLK 238 Query: 232 TKHLRRRPGHMTAE 245 PG E Sbjct: 239 ISPRMGEPGDYLIE 252 >2QDX-A nrPDB Length = 257 Score = 297 bits (760), Expect = 3e-81, Method: Composition-based stats. Identities = 88/253 (34%), Positives = 134/253 (52%), Gaps = 11/253 (4%) Query: 2 ADWVTGKVTKVQNWTDALFSL-TVHAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 ++ T +V V +W D LFS T P L F GQF +GLE+DG + RAYS + Sbjct: 1 SNLYTERVLSVHHWNDTLFSFKTTRNPGLRFKTGQFVMIGLEVDGRPLMRAYSIASPNYE 60 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 LEF+ + VPDG L+ RL LK GDE+ V + G V D++ + L++L+TGT + P Sbjct: 61 EHLEFFSIKVPDGPLTSRLQHLKEGDELMVSRKPTGTLVHDDLLPGKHLYLLSTGTGMAP 120 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVVS 173 +LS++Q + +R++ ++LVH R+ ++L+Y LP + + + KL +V+ Sbjct: 121 FLSVIQDPETYERYEKVILVHGVRWVSELAYADFITKVLPEHEYFGDQVKEKLIYYPLVT 180 Query: 174 RETAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLLKETRQMT 232 RE GR L+ SG+L IGL PMN + M+CG+P M+ +T +L Sbjct: 181 REPFRNQ--GRQTDLMRSGKLFEDIGLPPMNPQDDRAMICGSPSMLEETSAVLDSFGLKI 238 Query: 233 KHLRRRPGHMTAE 245 PG E Sbjct: 239 SPRMGEPGDYLIE 251 >4FK8-A nrPDB Length = 271 Score = 296 bits (757), Expect = 8e-81, Method: Composition-based stats. Identities = 94/254 (37%), Positives = 135/254 (53%), Gaps = 12/254 (4%) Query: 1 MADWVTGKVTKVQNWTDALFSLTV-HAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPD 59 M+ + T V V +WTD LFS T L F G+FT +GLE+DG+ + RAYS V+ Sbjct: 16 MSKFDTATVLSVHHWTDTLFSFTCTRDQALRFNNGEFTMVGLEVDGKPLTRAYSIVSPNY 75 Query: 60 NPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIG 119 LEF+ + V +G L+ RL LK GD V + + G V D + +TLWML+TGT + Sbjct: 76 EEHLEFFSIKVQNGPLTSRLQHLKVGDPVLIGKKPTGTLVADNLLPGKTLWMLSTGTGLA 135 Query: 120 PYLSILQLGKDLDRFKNLVLVHAARYAADLSY-------LPLMQELEKRYEGKLRIQTVV 172 P++SI++ +RF +VL H R +L+Y LP + L KL V Sbjct: 136 PFMSIIRDPDIYERFDKVVLTHTCRLKGELAYMDYIKHDLPGHEYLGDVIREKLVYYPTV 195 Query: 173 SRETAAGSLTGRIPALIESGELESTIGLPM-NKETSHVMLCGNPQMVRDTQQLLKETRQM 231 +RE GRI LI SG+L + + +P + E VMLCG+ M++DT +LLK+ + Sbjct: 196 TREEFENE--GRITDLIASGKLFTDLDMPPFSPEQDRVMLCGSTAMLKDTTELLKKA-GL 252 Query: 232 TKHLRRRPGHMTAE 245 + PGH E Sbjct: 253 VEGKNSAPGHYVIE 266 >4B4D-A nrPDB Length = 262 Score = 286 bits (731), Expect = 6e-78, Method: Composition-based stats. Identities = 83/253 (32%), Positives = 129/253 (50%), Gaps = 11/253 (4%) Query: 2 ADWVTGKVTKVQNWTDALFSLTVHAPV-LPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 + + V +V++WTDA FS T F GQF +GLE + + RAYS ++ Sbjct: 6 SAFGAETVLEVRHWTDAYFSFTTTRDAGFRFENGQFVMIGLETETRPLLRAYSIASANWE 65 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 LEF+ + VPDG L+ RL ++PGD+V V + G ++ ++ L++L TGT + P Sbjct: 66 EHLEFFSIKVPDGPLTSRLQHIQPGDKVLVGKKPTGTLLISDLHPGRNLYLLGTGTGLAP 125 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYL-------PLMQELEKRYEGKLRIQTVVS 173 +LSI++ + +RF ++L R+ DL+Y P + L KL V+ Sbjct: 126 WLSIIKDPETYERFDKVILTQGVRFVQDLAYRDYFERELPQHEFLGDLLREKLLYYPAVT 185 Query: 174 RETAAGSLTGRIPALIESGELESTIGLP-MNKETSHVMLCGNPQMVRDTQQLLKETRQMT 232 RET A GR+ L+ G ++ T+GLP ++ M+CG+PQM+ D + LL T Sbjct: 186 RETFANQ--GRLTELMADGRMQQTLGLPTLDPANDRFMICGSPQMLADLRSLLDSRGFQT 243 Query: 233 KHLRRRPGHMTAE 245 PGH E Sbjct: 244 SPRIGTPGHYVFE 256 >5UFA-A nrPDB Length = 267 Score = 265 bits (677), Expect = 1e-71, Method: Composition-based stats. Identities = 76/252 (30%), Positives = 126/252 (50%), Gaps = 8/252 (3%) Query: 2 ADWVTGKVTKVQNWTDALFSLTVHAP-VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 A + K+ V++ T L + + P F AGQF++LG + RAYS V++ Sbjct: 15 AKFTEEKILWVKHHTPKLITFAISRPESYRFKAGQFSRLGFYEGKGFIWRAYSVVSAEYA 74 Query: 61 PDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 LE++ V + DG +S A ++ GD + + A GF + + P + L ML TG+ I P Sbjct: 75 DTLEYFAVLIQDGPMSALFAKMQQGDTILLDKNATGFLLPERFPDGKDLVMLCTGSGIAP 134 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK-----RYEGKLRIQTVVSRE 175 +LSIL+ + RF + L+H+ + +L + + L + Y R V +R Sbjct: 135 FLSILEQPEIRQRFDTVNLIHSVSFPEELIFNDRLAALSEHPLVGEYGHSFRFVPVTTRA 194 Query: 176 TAAGSLTG-RIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKH 234 L+G RIP L+++ +E + + E++ M+CGNP+MV+DT Q L + H Sbjct: 195 ANPSGLSGKRIPELLKNNSIEQALHTKLTPESTRFMICGNPEMVKDTFQTLLDM-GYAMH 253 Query: 235 LRRRPGHMTAEH 246 R PG + E+ Sbjct: 254 RNRIPGQIMMEN 265 >2VNH-A nrPDB Length = 272 Score = 258 bits (658), Expect = 2e-69, Method: Composition-based stats. Identities = 81/251 (32%), Positives = 133/251 (52%), Gaps = 13/251 (5%) Query: 5 VTGKVTKVQNWTDALFSLTVHAP-VLPFTAGQFTKLGL-EIDGERVQRAYSYVNSPDNPD 62 VT V++WTD LFS V P L F +G+F +GL + +G+ + RAYS + + + Sbjct: 17 DAQTVTSVRHWTDTLFSFRVTRPQTLRFRSGEFVMIGLLDDNGKPIMRAYSIASPAWDEE 76 Query: 63 LEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYL 122 LEFY + VPDG L+ RL +K G+++ + + G V+D + + LW LATGT I P+ Sbjct: 77 LEFYSIKVPDGPLTSRLQHIKVGEQIILRPKPVGTLVIDALLPGKRLWFLATGTGIAPFA 136 Query: 123 SILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQE-------LEKRYEGKLRIQTVVSRE 175 S+++ + ++F ++++HA R A+L Y + E + + EGKL+ +RE Sbjct: 137 SLMREPEAYEKFDEVIMMHACRTVAELEYGRQLVEALQEDPLIGELVEGKLKYYPTTTRE 196 Query: 176 TAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKH 234 GRI + SG++ +G+ PMN ET M+CG+ D ++L E+ + + Sbjct: 197 EF--HHMGRITDNLASGKVFEDLGIAPMNPETDRAMVCGSLAFNVDVMKVL-ESYGLREG 253 Query: 235 LRRRPGHMTAE 245 P E Sbjct: 254 ANSEPREFVVE 264 >2EIX-A nrPDB Length = 243 Score = 196 bits (497), Expect = 9e-51, Method: Composition-based stats. Identities = 52/229 (22%), Positives = 96/229 (41%), Gaps = 14/229 (6%) Query: 11 KVQNWTDALFSLTVHAP--VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD-LEFYL 67 ++ N LF +H P V+ GQ + +DG+ + R Y+ V+S D + + Sbjct: 20 QIINHNTRLFRFNLHHPEDVVGLPIGQHMSVKATVDGKEIYRPYTPVSSDDEKGYFDLII 79 Query: 68 VTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPH-CETLWMLATGTAIGPYLSILQ 126 G++S + L PGD +QV F D P+ + + M+A GT I P L + + Sbjct: 80 KVYEKGQMSQYIDHLNPGDFLQVRGPKGQF---DYKPNMVKEMGMIAGGTGITPMLQVAR 136 Query: 127 LGKDLDRFKNLV-LVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRI 185 + K ++ L+ A D+ + ++ K+Y ++ V++ A TG + Sbjct: 137 AIIKNPKEKTIINLIFANVNEDDILLRTELDDMAKKYS-NFKVYYVLNNPPAGW--TGGV 193 Query: 186 PALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKH 234 + + ++ P VM+CG P M + Q L+ + Sbjct: 194 -GFVSADMIKQHFSPP--SSDIKVMMCGPPMMNKAMQGHLETLGYTPEQ 239 >3W2G-A nrPDB Length = 271 Score = 186 bits (471), Expect = 1e-47, Method: Composition-based stats. Identities = 55/252 (21%), Positives = 97/252 (38%), Gaps = 32/252 (12%) Query: 11 KVQNWTDALFSLTVHAP--VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLV 68 +V N F + +P +L GQ L IDG V R Y+ V+S D+ ++ Sbjct: 21 EVVNHDTRRFRFALPSPEHILGLPVGQHIYLSARIDGNLVIRPYTPVSSDDDKGFVDLVI 80 Query: 69 TV----------PDGKLSPRLAALKPGDEVQVVSEAA-------GFFVLDE-------VP 104 V GK+S L ++K GD ++ G F + + Sbjct: 81 KVYFKDTHPKFPAGGKMSQYLESMKIGDTIEFRGPNGLLVYQGKGKFAIRPDKKSSPVIK 140 Query: 105 HCETLWMLATGTAIGPYLSILQ-LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYE 163 +++ M+A GT I P L +++ + KD D L+ A + D+ P ++EL + Sbjct: 141 TVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNEHS 200 Query: 164 GKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQ 223 + ++ V R A + + + + P +E V++CG P M++ Sbjct: 201 ARFKLWYTVDRAPEAWDYSQ---GFVNEEMIRDHL--PPPEEEPLVLMCGPPPMIQYACL 255 Query: 224 LLKETRQMTKHL 235 E K Sbjct: 256 PNLERVGHPKER 267 >3OZU-A nrPDB Length = 403 Score = 185 bits (469), Expect = 2e-47, Method: Composition-based stats. Identities = 55/249 (22%), Positives = 107/249 (42%), Gaps = 26/249 (10%) Query: 4 WVTGKVTKVQNWTDALFSLTVH----APVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPD 59 W T + + + +D + S + PV+ F GQ+T + +++ +Q+ Y S D Sbjct: 154 WRTFVIREKRPESDVITSFILEPADGGPVVNFEPGQYTSVAIDVPALGLQQIRQYSLS-D 212 Query: 60 NPDLEFYLVTV--------PDGKLSPRL-AALKPGDEVQVVSEAAGFFVLDEVPHCETLW 110 P+ Y ++V P G +S L + GD+V++ + F + +V + Sbjct: 213 MPNGRSYRISVKREGGGPQPPGYVSNLLHDHVNVGDQVKLAAPYGSFHI--DVDAKTPIV 270 Query: 111 MLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQT 170 +++ G + P +S+L++ + +V VH AR +A + ++E K YE L + Sbjct: 271 LISGGVGLTPMVSMLKVALQAPP-RQVVFVHGARNSAVHAMRDRLREAAKTYE-NLDL-F 327 Query: 171 VVSRETAAGSLTGR---IPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKE 227 V + + GR P L++ ++E +I LP + +CG +R LK Sbjct: 328 VFYDQPLPEDVQGRDYDYPGLVDVKQIEKSILLP----DADYYICGPIPFMRMQHDALKN 383 Query: 228 TRQMTKHLR 236 + Sbjct: 384 LGIHEARIH 392 >1KRH-A nrPDB Length = 338 Score = 184 bits (467), Expect = 3e-47, Method: Composition-based stats. Identities = 60/236 (25%), Positives = 98/236 (41%), Gaps = 27/236 (11%) Query: 6 TGKVTKVQNWTDALFSLTVH----APVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNP 61 G + +V+N +D+ + + P + F AGQ+ + L G R+YS+ + P N Sbjct: 110 EGTLARVENLSDSTITFDIQLDDGQPDIHFLAGQYVNVTL--PGTTETRSYSFSSQPGNR 167 Query: 62 DLEFYLVTVPDGKLSPRLAA-LKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGP 120 F + VP GK+S L+ K GD++ F++ D + MLA GT I P Sbjct: 168 LTGFVVRNVPQGKMSEYLSVQAKAGDKMSFTGPFGSFYLRDVK---RPVLMLAGGTGIAP 224 Query: 121 YLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKR---YEGKLRIQTVVSRETA 177 +LS+LQ+ + + LV DL L + L+++ +E + + S+ Sbjct: 225 FLSMLQVLEQKGSEHPVRLVFGVTQDCDLVALEQLDALQQKLPWFEYRTVVAHAESQHER 284 Query: 178 AGSLTGRI-PALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMT 232 G +TG I + GE+ V LCG MV + L Sbjct: 285 KGYVTGHIEYDWLNGGEV-------------DVYLCGPVPMVEAVRSWLDTQGIQP 327 >4WQM-A nrPDB Length = 326 Score = 183 bits (463), Expect = 9e-47, Method: Composition-based stats. Identities = 51/219 (23%), Positives = 95/219 (43%), Gaps = 16/219 (7%) Query: 8 KVTKVQNWTDALFSLTVHAP-VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFY 66 +V + +D +F L + A + F+ GQ+ + + E RAYS N D L Sbjct: 106 RVVSKRFLSDEMFELRLEAEQKVVFSPGQYFMVDVP---ELGTRAYSAANPVDGNTLTLI 162 Query: 67 LVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQ 126 + VP+GK+S LA E + G VL ++++ +A G+ I P +S++ Sbjct: 163 VKAVPNGKVSCALA--NETIETLQLDGPYGLSVLKTADETQSVF-IAGGSGIAPMVSMVN 219 Query: 127 LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIP 186 K + + + +R A+L + ++ + + + + V + + TG + Sbjct: 220 TLIAQGYEKPITVFYGSRLEAELEAAETLFGWKENLK-LINVSSSVVGNSESSYPTGYVH 278 Query: 187 ALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLL 225 +I +E +G + LCG PQM+ Q+LL Sbjct: 279 EIIPE-YMEGLLG-------AEFYLCGPPQMINSVQKLL 309 >1UMK-A nrPDB Length = 275 Score = 176 bits (446), Expect = 9e-45, Method: Composition-based stats. Identities = 48/237 (20%), Positives = 96/237 (40%), Gaps = 32/237 (13%) Query: 10 TKVQNWTDALFSLTVHAP--VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYL 67 ++ + F + +P +L GQ L IDG V R Y+ ++S D+ + Sbjct: 24 REIISHDTRRFRFALPSPQHILGLPVGQHIYLSARIDGNLVVRPYTPISSDDDKGFVDLV 83 Query: 68 VTV----------PDGKLSPRLAALKPGDEVQVVSEAA-------GFFVLDE-------V 103 + V GK+S L +++ GD ++ + G F + + Sbjct: 84 IKVYFKDTHPKFPAGGKMSQYLESMQIGDTIEFRGPSGLLVYQGKGKFAIRPDKKSNPII 143 Query: 104 PHCETLWMLATGTAIGPYLSILQ-LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRY 162 +++ M+A GT I P L +++ + KD D L+ A + D+ P ++EL ++ Sbjct: 144 RTVKSVGMIAGGTGITPMLQVIRAIMKDPDDHTVCHLLFANQTEKDILLRPELEELRNKH 203 Query: 163 EGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVR 219 + ++ + R A + + + P +E V++CG P M++ Sbjct: 204 SARFKLWYTLDRAPEAWDYGQ---GFVNEEMIRDHL--PPPEEEPLVLMCGPPPMIQ 255 >5OGX-A nrPDB Length = 336 Score = 173 bits (439), Expect = 6e-44, Method: Composition-based stats. Identities = 57/219 (26%), Positives = 85/219 (38%), Gaps = 21/219 (9%) Query: 26 APVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD-LEFYLVTVP-----DGKLSPRL 79 A L F AGQ+ + L + G +R YS N+ D LE ++ VP DG L L Sbjct: 125 AEPLAFEAGQYVE--LVVPGSGARRQYSLANTADEDKVLELHVRRVPGGVATDGWLFDGL 182 Query: 80 AALKPGDEVQVVSEAAGFFVLD-EVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLV 138 AA GD V+ F + + + ++ GT + P + I + + ++ Sbjct: 183 AA---GDRVEATGPLGDFHLPPPDEDDGGPMVLIGGGTGLAPLVGIARTALARHPSREVL 239 Query: 139 LVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTI 198 L H R AADL L E+ + + G R V+S E G Sbjct: 240 LYHGVRGAADLYDLGRFAEIAEEHPG-FRFVPVLSDEPDPAYRGGFPTDAFVED------ 292 Query: 199 GLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHLRR 237 +P + S LCG P MV + K R + + R Sbjct: 293 -VPSGRGWSG-WLCGPPAMVEAGVKAFKRRRMSPRRIHR 329 >2B5O-A nrPDB Length = 402 Score = 141 bits (356), Expect = 2e-34, Method: Composition-based stats. Identities = 57/257 (22%), Positives = 97/257 (37%), Gaps = 34/257 (13%) Query: 21 SLTVHAPVLPFTAGQFTKL---GLEIDGER-VQRAYSYVNS-----PDNPDLEFYLVT-- 69 + + L + GQ + G + +G+ R YS ++ DN + + Sbjct: 146 TFDISEGDLRYLEGQSIGIIPPGEDKNGKPHKLRLYSIASTRHGDMEDNKTVSLCVRQLE 205 Query: 70 VPD--------GKLSPRLAALKPG-DEVQVVSEAA-GFFVLDEVPHCETLWMLATGTAIG 119 D G S L L G D+V++ + D+ T+ MLATGT I Sbjct: 206 YQDPESGETVYGVCSTYLCNLPVGTDDVKITGPVGKEMLLPDDEDA--TVVMLATGTGIA 263 Query: 120 PYLSIL-QLGKDLD---RFKNLV-LVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSR 174 P+ + L ++ K+ +FK L+ Y A++ Y +++ R+ +SR Sbjct: 264 PFRAFLWRMFKEQHEDYKFKGKAWLIFGVPYTANILYKDDFEKMAAENPDNFRLTYAISR 323 Query: 175 ETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQM---VRDTQQLLKETRQM 231 E G++ E + + K +HV +CG M + +T E R + Sbjct: 324 EQKTAD-GGKVYVQSRVSEYADELFEMIQKPNTHVYMCGLKGMQPPIDETFTAEAEKRGL 382 Query: 232 TKHLRRRPGHMTAEHYW 248 RR M EH W Sbjct: 383 NWEEMRR--SMKKEHRW 397 >1GVH-A nrPDB Length = 396 Score = 105 bits (262), Expect = 2e-23, Method: Composition-based stats. Identities = 44/241 (18%), Positives = 87/241 (36%), Gaps = 16/241 (6%) Query: 5 VTGKVTKVQNWTDALFSLTVH----APVLPFTAGQFTKLGLEIDGER--VQRAYSYVNSP 58 ++ + + S + V + GQ+ + L+ +G R YS P Sbjct: 153 RDFRIVAKTPRSALITSFELEPVDGGAVAEYRPGQYLGVWLKPEGFPHQEIRQYSLTRKP 212 Query: 59 DNPDLEFYLVTVPDGKLSPRL-AALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTA 117 D + G++S L GD V++V+ A FF+ V + +++ G Sbjct: 213 DGKGYRIAVKREEGGQVSNWLHNHANVGDVVKLVAPAGDFFMA--VADDTPVTLISAGVG 270 Query: 118 IGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETA 177 P L++L + HAA ++ ++EL + + T + + Sbjct: 271 QTPMLAMLDTLAKAGHTAQVNWFHAAENGDVHAFADEVKELGQSLP-RFTAHTWYRQPSE 329 Query: 178 AGSLTGRI--PALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETRQMTKHL 235 A G+ L++ +LE P T LCG ++ T + L + +++ Sbjct: 330 ADRAKGQFDSEGLMDLSKLEGAFSDP----TMQFYLCGPVGFMQFTAKQLVDLGVKQENI 385 Query: 236 R 236 Sbjct: 386 H 386 >4U9U-A nrPDB Length = 281 Score = 104 bits (259), Expect = 4e-23, Method: Composition-based stats. Identities = 38/195 (19%), Positives = 64/195 (32%), Gaps = 16/195 (8%) Query: 46 ERVQRAYSYVNSPDNPDLEFYLVTVP----------DGKLSPRLAALKPGDEVQVVSEAA 95 E + RAYS N P+ + V + G++S + +LK GD+ + Sbjct: 79 EPIIRAYSMANYPEEFGIIMLNVRIATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFG 138 Query: 96 GFFVLDEVPHCETLWMLATGTAIGPYLS-ILQLGKDLDRFKNLVLVHAARYAADLSYLPL 154 FF + + G + P S I K L + + + AR ++ Y+ Sbjct: 139 EFFA---KDTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVED 195 Query: 155 MQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGN 214 L +S + TG I + E+ + E +CG Sbjct: 196 FDGLAAEN-DNFVWHCALSDPQPEDNWTGY-TGFIHNVLYENYLKDHEAPEDCEYYMCGP 253 Query: 215 PQMVRDTQQLLKETR 229 P M +LK Sbjct: 254 PMMNAAVINMLKNLG 268 >4P6V-F nrPDB Length = 408 Score = 104 bits (259), Expect = 4e-23, Method: Composition-based stats. Identities = 38/195 (19%), Positives = 64/195 (32%), Gaps = 16/195 (8%) Query: 46 ERVQRAYSYVNSPDNPDLEFYLVTVP----------DGKLSPRLAALKPGDEVQVVSEAA 95 E + RAYS N P+ + V + G++S + +LK GD+ + Sbjct: 206 EPIIRAYSMANYPEEFGIIMLNVRIATPPPNNPNVPPGQMSSYIWSLKAGDKCTISGPFG 265 Query: 96 GFFVLDEVPHCETLWMLATGTAIGPYLS-ILQLGKDLDRFKNLVLVHAARYAADLSYLPL 154 FF + + G + P S I K L + + + AR ++ Y+ Sbjct: 266 EFFA---KDTDAEMVFIGGGAGMAPMRSHIFDQLKRLKSKRKMSYWYGARSKREMFYVED 322 Query: 155 MQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGN 214 L +S + TG I + E+ + E +CG Sbjct: 323 FDGLAAEN-DNFVWHCALSDPQPEDNWTGY-TGFIHNVLYENYLKDHEAPEDCEYYMCGP 380 Query: 215 PQMVRDTQQLLKETR 229 P M +LK Sbjct: 381 PMMNAAVINMLKNLG 395 >2R6H-A nrPDB Length = 290 Score = 100 bits (248), Expect = 7e-22, Method: Composition-based stats. Identities = 34/198 (17%), Positives = 68/198 (34%), Gaps = 12/198 (6%) Query: 36 FTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAA 95 ++ +G + P + + + G S + +LKPGD+V + Sbjct: 89 YSMANYPAEGNIITLNVRIATPPFDRAANKWKAGIKPGISSSYIFSLKPGDKVMMSGPYG 148 Query: 96 GFFVLDEVPHCETLWMLATGTAIGPYL-SILQLGKDLDRFKNLVLVHAARYAADLSYLPL 154 F + D + + G + P IL L + L + + + AR ++ Y Sbjct: 149 DFHIQDT---DAEMLYIGGGAGMAPLRAQILHLFRTLKTGRKVSYWYGARSKNEIFYEED 205 Query: 155 MQELEKRYEGKLRIQTVVSRETAAGSLTGR---IPALIESGELESTIGLPMNKETSHVML 211 +E+E+ + + +S + TG I +I L+ E + Sbjct: 206 FREIEREFP-NFKFHIALSDPQPEDNWTGYVGFIHQVIYDNYLKDH----DAPEDIEYYM 260 Query: 212 CGNPQMVRDTQQLLKETR 229 CG M + +L+ Sbjct: 261 CGPGPMANAVKGMLENLG 278 >6O0A-A nrPDB Length = 413 Score = 84.8 bits (208), Expect = 4e-17, Method: Composition-based stats. Identities = 28/207 (13%), Positives = 69/207 (33%), Gaps = 17/207 (8%) Query: 32 TAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTV-PDGKLSPRLAALKPGDEVQV 90 AGQ+ + + + + + P + + P G+++ + G + + Sbjct: 203 KAGQYISIYART-SDGLLQPRQFTLLPSEETQRRIAIKLDPHGEMTTIFQNQEVGALLDI 261 Query: 91 VSEAAG-FFVLDEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADL 149 + E L ++ G + P L+ ++ + ++++ ++R A+ Sbjct: 262 SNPYGDMTLETLETDPNSPLVLICAGIGVTPVLAFVEKLAAQKSEREVMIIASSRSLAEA 321 Query: 150 SYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHV 209 + E K + + + G GRI + + V Sbjct: 322 PLRGELLERAKELKKAKVLYGTT--QEKDGDFVGRI-----------DVSTLDIPANASV 368 Query: 210 MLCGNPQMVRDTQQLLKETRQMTKHLR 236 LCG + +++ + L E + KH Sbjct: 369 FLCGPLKFMQEMRSHLVEA-GIAKHKI 394 >4G1B-A nrPDB Length = 399 Score = 83.2 bits (204), Expect = 9e-17, Method: Composition-based stats. Identities = 45/257 (17%), Positives = 89/257 (34%), Gaps = 37/257 (14%) Query: 4 WVTGKVTKVQNWTDALFSLT--------VHAPVLPFTAGQFTKLGL----EIDGERVQRA 51 W ++T + + T + LP T GQ+ + + + R Sbjct: 149 WKPFEITAKEYVASDIVEFTVKPKFGSGIELESLPITPGQYITVNTHPIRQENQYDALRH 208 Query: 52 YSYVNSPDNPDLEFYLV------TVPDGKLSPRLAA-LKPGDEVQVVSEAAGFFVLDEVP 104 YS ++ L F + P G +S L K GDE+++ + A F + E+ Sbjct: 209 YSLCSASTKNGLRFAVKMEAARENFPAGLVSEYLHKDAKVGDEIKLSAPAGDFAINKELI 268 Query: 105 HCE--TLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRY 162 H L +L++G + P L++L+ + + + + ++ ++ + EL Sbjct: 269 HQNEVPLVLLSSGVGVTPLLAMLEEQVKCNPNRPIYWIQSSYDEKTQAFKKHVDELLAEC 328 Query: 163 EGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQ 222 +I E LI + L+ + + V CG+ ++ Sbjct: 329 ANVDKIIVHTDTEP-----------LINAAFLKEK-----SPAHADVYTCGSLAFMQAMI 372 Query: 223 QLLKETRQMTKHLRRRP 239 LKE + P Sbjct: 373 GHLKELEHRDDMIHYEP 389 >4EH1-A nrPDB Length = 243 Score = 82.1 bits (201), Expect = 2e-16, Method: Composition-based stats. Identities = 43/235 (18%), Positives = 86/235 (36%), Gaps = 28/235 (11%) Query: 3 DWVTGKVTKVQNWTDALFSLTV----HAPVLPFTAGQFTKLGLEIDGE--RVQRAYSYVN 56 D T V + Q + + S + VL + GQ+ + + +G R R YS + Sbjct: 2 DGRTFVVREKQVESAYVTSFVLVPADGGAVLDYQPGQYIGIEVTPEGSDYREIRQYSLSH 61 Query: 57 SPDNPDLEFYLVTV-----PDGKLSPRL-AALKPGDEVQVVSEAAGFFVLDEVPHCETLW 110 + + + + G +S L +K GD V++ + A FF V + Sbjct: 62 ASNGREYRISVKREGVGSDNPGLVSHYLHNNVKVGDSVKLYAPAGDFF---YVERERPVV 118 Query: 111 MLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQT 170 +++ G P +IL ++ + ++A A + ++ +L + ++ Sbjct: 119 LISAGVGATPMQAILHTLAKQNKS-GVTYLYACNSAKEHTFAQETAQLIAQQGWMQQVWY 177 Query: 171 VVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLL 225 E+A L G + + LP+ E LCG ++ + L Sbjct: 178 --RDESADDVLQG--------EMQLAELILPI--EDGDFYLCGPIGFMQYVVKQL 220 >1QFJ-A nrPDB Length = 232 Score = 80.9 bits (198), Expect = 4e-16, Method: Composition-based stats. Identities = 42/225 (18%), Positives = 87/225 (38%), Gaps = 16/225 (7%) Query: 8 KVTKVQNWTDALFSLTV-HAPVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDL-EF 65 KVT V+ TD ++ + + F AGQ+ + ++ ER +R +S ++PD E Sbjct: 6 KVTSVEAITDTVYRVRIVPDAAFSFRAGQYLMVVMD---ERDKRPFSMASTPDEKGFIEL 62 Query: 66 YLVTVP-DGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSI 124 ++ + + + ++ V ++ D + ++A GT SI Sbjct: 63 HIGASEINLYAKAVMDRILKDHQIVVDIPHGEAWLRD--DEERPMILIAGGTGFSYARSI 120 Query: 125 LQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGR 184 L + +++ + R L L ++ L ++ G L++ VV + A GR Sbjct: 121 LLTALARNPNRDITIYWGGREEQHLYDLCELEALSLKHPG-LQVVPVVEQPEAGW--RGR 177 Query: 185 IPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKETR 229 + + L+ L + + G +M + + L R Sbjct: 178 -TGTVLTAVLQDHGTL----AEHDIYIAGRFEMAKIARDLFCSER 217 >1TLL-A nrPDB Length = 688 Score = 72.5 bits (176), Expect = 2e-13, Method: Composition-based stats. Identities = 43/199 (21%), Positives = 77/199 (38%), Gaps = 28/199 (14%) Query: 50 RAYSYVNSPD----NPDLEFYLVT---------VPDGKLSPRLAALKPGDEVQ-VVSEAA 95 R YS +SPD L +V+ V G S L ++ D V V A Sbjct: 432 RYYSISSSPDMYPDEVHLTVAIVSYHTRDGEGPVHHGVCSSWLNRIQADDVVPCFVRGAP 491 Query: 96 GFFVLDEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFK-----NLVLVHAARYAA-DL 149 F + ++ GT I P+ S Q + + K +VLV R + D Sbjct: 492 SFHLPRN--PQVPCILVGPGTGIAPFRSFWQQRQFDIQHKGMNPCPMVLVFGCRQSKIDH 549 Query: 150 SYLPLMQELEKRYEGKLR-IQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSH 208 Y + L+ + +G R + T SRE + +++ +L ++ + ++ H Sbjct: 550 IYRE--ETLQAKNKGVFRELYTAYSREPDR--PKKYVQDVLQE-QLAESVYRALKEQGGH 604 Query: 209 VMLCGNPQMVRDTQQLLKE 227 + +CG+ M D + ++ Sbjct: 605 IYVCGDVTMAADVLKAIQR 623 >4YRY-A nrPDB Length = 276 Score = 64.8 bits (156), Expect = 3e-11, Method: Composition-based stats. Identities = 33/154 (21%), Positives = 59/154 (38%), Gaps = 9/154 (5%) Query: 9 VTKVQNWTDALFSLTVHAPVLPFT--AGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFY 66 + K + +F +H+P + GQF + L GER+ + ++ L Sbjct: 9 IVKKVKIAEDVFDFWIHSPSVSKEARPGQFVVIRLHEKGERI--PLTVADTKPEEGLFRM 66 Query: 67 LVTVPDGKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQ 126 +V V GK + L+ K GD + V G E+ + + ++ G I I + Sbjct: 67 VVKVV-GKTTHELSLKKEGDTILDVVGPLGN--PSEIENYGNVLLVGGGVGIATLYPIAK 123 Query: 127 LGKDLDRFKNLVLVHAARYAADLSYLPLMQELEK 160 K+ N+ V AR L + +E+ Sbjct: 124 ALKEAG--NNITTVLGARTKDYLIMVDEFKEISD 155 >5KSW-B nrPDB Length = 262 Score = 62.1 bits (149), Expect = 2e-10, Method: Composition-based stats. Identities = 30/225 (13%), Positives = 83/225 (36%), Gaps = 26/225 (11%) Query: 8 KVTKVQNWTDALFSLTVHAPVLPF--TAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEF 65 + + +F + + ++ GQF L + ++R S + + + Sbjct: 9 TIVSQREVASNIFEMVLKGELVEEMDLPGQFLHLAVPNASMLLRRPISISS--WDKVAKT 66 Query: 66 YLVTVPDGKLSPR---LAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAIGPYL 122 + G + ++ L+ G ++ V+ F +DEV + + ++ G + P Sbjct: 67 CTILYRIGDETSGTYEISKLQSGAKIDVMGPLGNGFPVDEVVSTDKILIVGGGIGVPPLY 126 Query: 123 SILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLT 182 + + ++ + ++L A+ ++ LEK + + ++ + + Sbjct: 127 ELAKQLEEKNCQMTILLGFAS---------EKVKILEKEFAELKNVSLKIATDDGSYGTK 177 Query: 183 GRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLKE 227 G + L+E ++ E + CG P M++ + ++ Sbjct: 178 GHVGMLMEE----------IDFEVDALYTCGAPAMLKAVAKKYEQ 212 >2PIA-A nrPDB Length = 321 Score = 60.1 bits (144), Expect = 8e-10, Method: Composition-based stats. Identities = 35/226 (15%), Positives = 72/226 (31%), Gaps = 35/226 (15%) Query: 8 KVTKVQNWTDALFSLTVH----APVLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDL 63 K+ + ++S + AP+ PF AG + + +R YS N + Sbjct: 12 KIASKEKIARDIWSFELTDPQGAPLPPFEAGANLTVAVP---NGSRRTYSLCNDSQERNR 68 Query: 64 EFYLVTVPD-----GKLSPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLATGTAI 118 Y++ V G + GD V+V F + ++ ++A G I Sbjct: 69 --YVIAVKRDSNGRGGSISFIDDTSEGDAVEVSLPRNEFPLDKRA---KSFILVAGGIGI 123 Query: 119 GPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAA 178 P LS+ + + ++ L + R ++ + + ++I T A Sbjct: 124 TPMLSMARQLRAEG-LRSFRLYYLTRDPEGTAFFDELT--SDEWRSDVKIHHDHGDPTKA 180 Query: 179 GSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQL 224 ++ HV CG ++ + + Sbjct: 181 FD--------------FWSVFEKSKPAQ-HVYCCGPQALMDTVRDM 211 >2BN4-A nrPDB Length = 682 Score = 56.3 bits (134), Expect = 1e-08, Method: Composition-based stats. Identities = 20/135 (14%), Positives = 43/135 (31%), Gaps = 16/135 (11%) Query: 102 EVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNL----------VLVHAARYAADLSY 151 + M+ GT + P+ ++ + +L + +R D Y Sbjct: 520 PSNPSTPVIMIGPGTGVAPFRGFIRERVAFLESQKKGGNNVSLGKHILFYGSRNTDDFLY 579 Query: 152 LPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVML 211 E K+ +G + SR T ++ + + E + +N + + + Sbjct: 580 QDEWPEYAKKLDGSFEMVVAHSRLPN----TKKVYVQDKLKDYEDQVFEMINNG-AFIYV 634 Query: 212 CG-NPQMVRDTQQLL 225 CG M + L Sbjct: 635 CGDAKGMAKGVSTAL 649 >6EFV-A nrPDB Length = 569 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 40/218 (18%), Positives = 72/218 (33%), Gaps = 32/218 (14%) Query: 29 LPFTAGQFTKLGLEIDGERVQ-RAYSYVNSPDNPDLEFYLV----------TVPDGKLSP 77 + F+ Q L + R YS +S + E ++ G S Sbjct: 334 VRFSPAQLDAEALINLLRPLTPRLYSIASSQAEVENEVHVTVGVVRYDVEGRARAGGASS 393 Query: 78 RLAALKPGDEVQVVSEAAGFFVLDE-----VPHCETLWMLATGTAIGPYLSILQLGKDLD 132 LA D V+ E F ++ + M+ GT I P+ + +Q + Sbjct: 394 FLA-----DRVEEEGEVRVFIEHNDNFRLPANPETPVIMIGPGTGIAPFRAFMQQRAADE 448 Query: 133 RFKNLVLVHAAR-YAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIES 191 L + D Y E ++ + V++R A S + ++ Sbjct: 449 APGKNWLFFGNPHFTEDFLYQ---VEWQRYVKEG-----VLTRIDLAWSRDQKEKVYVQD 500 Query: 192 GELESTIGLPMNKET-SHVMLCGNP-QMVRDTQQLLKE 227 E L +H+ +CG+ +M +D +Q L E Sbjct: 501 KLREQGAELWRWINDGAHIYVCGDANRMAKDVEQALLE 538 >3ES9-A nrPDB Length = 618 Score = 52.0 bits (123), Expect = 2e-07, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 46/132 (34%), Gaps = 12/132 (9%) Query: 102 EVPHCETLWMLATGTAIGPYLSILQL---GKDLDRF-KNLVLVHAA-RYAADLSYLPLMQ 156 + M+ GT I P++ +Q ++ + +L + R D Y + Sbjct: 461 PFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELA 520 Query: 157 ELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQ 216 K ++ SRE A + + +++ +H+ +CG+ + Sbjct: 521 RFHKD-GALTQLNVAFSREQAHKVYVQHLL-----KRDREHLWKLIHEGGAHIYVCGDAR 574 Query: 217 -MVRDTQQLLKE 227 M +D Q + Sbjct: 575 NMAKDVQNTFYD 586 >6J79-A nrPDB Length = 871 Score = 50.9 bits (120), Expect = 5e-07, Method: Composition-based stats. Identities = 21/132 (15%), Positives = 46/132 (34%), Gaps = 12/132 (9%) Query: 102 EVPHCETLWMLATGTAIGPYLSILQL---GKDLDRF-KNLVLVHAA-RYAADLSYLPLMQ 156 + M+ GT I P++ +Q ++ + +L + R D Y + Sbjct: 714 PFKSTTPVIMVGPGTGIAPFMGFIQERAWLREQGKEVGETLLYYGCRRSDEDYLYREELA 773 Query: 157 ELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQ 216 K ++ SRE A + + +++ +H+ +CG+ + Sbjct: 774 RFHKD-GALTQLNVAFSREQAHKVYVQHLL-----KRDREHLWKLIHEGGAHIYVCGDAR 827 Query: 217 -MVRDTQQLLKE 227 M +D Q + Sbjct: 828 NMAKDVQNTFYD 839 >5GXU-A nrPDB Length = 640 Score = 47.8 bits (112), Expect = 5e-06, Method: Composition-based stats. Identities = 42/247 (17%), Positives = 78/247 (31%), Gaps = 42/247 (17%) Query: 2 ADWVTGKVTKVQNWTDALFSLTVHAPVLP-FTAGQFTKLGLEIDGERVQRAYSYVNSPDN 60 + WV ++ + + P L F AG + R YS +SP Sbjct: 380 SKWVVE---SQRSLLEVMAEFPSAKPPLGVFFAG--------VAPRLQPRFYSISSSPKI 428 Query: 61 PDLEFYLV------TVPDGKL-----SPRLAALKPGDEVQVVSEAAGFFVLDEV----PH 105 + ++ +P G++ S + P ++ + S A F Sbjct: 429 AETRIHVTCALVYEKMPTGRIHKGVCSTWMKNAVPYEKSENCSSAPIFVRQSNFKLPSDS 488 Query: 106 CETLWMLATGTAIGPYLSILQL----GKDLDRFKNLVLVHAARYAA-DLSYLPLMQELEK 160 + M+ GT + P+ LQ + VL R D Y +Q + Sbjct: 489 KVPIIMIGPGTGLAPFRGFLQERLALVESGVELGPSVLFFGCRNRRMDFIYEEELQRFVE 548 Query: 161 RYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGL-PMNKETSHVMLCG-NPQMV 218 + SRE G ++ ++ + M + +++ +CG M Sbjct: 549 S-GALAELSVAFSRE-------GPTKEYVQHKMMDKASDIWNMISQGAYLYVCGDAKGMA 600 Query: 219 RDTQQLL 225 RD + L Sbjct: 601 RDVHRSL 607 >3FJO-A nrPDB Length = 637 Score = 47.4 bits (111), Expect = 6e-06, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 46/132 (34%), Gaps = 13/132 (9%) Query: 102 EVPHCETLWMLATGTAIGPYLSILQL---GKDLDRF-KNLVLVHAA-RYAADLSYLPLMQ 156 + M+ GT + P++ +Q + + +L + R D Y + Sbjct: 481 PFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELA 540 Query: 157 ELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQ 216 + R ++ SRE + + + + + + +H+ +CG+ + Sbjct: 541 QF-HRDGALTQLNVAFSREQSHKVYVQHLL-----KQDREHLW-KLIEGGAHIYVCGDAR 593 Query: 217 -MVRDTQQLLKE 227 M RD Q + Sbjct: 594 NMARDVQNTFYD 605 >3QFR-A nrPDB Length = 618 Score = 47.0 bits (110), Expect = 6e-06, Method: Composition-based stats. Identities = 20/132 (15%), Positives = 46/132 (34%), Gaps = 13/132 (9%) Query: 102 EVPHCETLWMLATGTAIGPYLSILQL---GKDLDRF-KNLVLVHAA-RYAADLSYLPLMQ 156 + M+ GT + P++ +Q + + +L + R D Y + Sbjct: 462 PFKATTPVIMVGPGTGVAPFIGFIQERAWLRQQGKEVGETLLYYGCRRSDEDYLYREELA 521 Query: 157 ELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHVMLCGNPQ 216 + R ++ SRE + + + + + + +H+ +CG+ + Sbjct: 522 QF-HRDGALTQLNVAFSREQSHKVYVQHLL-----KQDREHLW-KLIEGGAHIYVCGDAR 574 Query: 217 -MVRDTQQLLKE 227 M RD Q + Sbjct: 575 NMARDVQNTFYD 586 >5O0X-A nrPDB Length = 291 Score = 45.9 bits (107), Expect = 1e-05, Method: Composition-based stats. Identities = 30/252 (11%), Positives = 67/252 (26%), Gaps = 56/252 (22%) Query: 18 ALFSLTVHAP-VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPD-LEFYLVTVPD--G 73 + L V P + G + + + ++ ++P+ PD L ++ V G Sbjct: 16 KVLGLQVQRPQSFNYQPGDYLFIKCPGISKFEWHPFTISSAPEMPDVLTLHIRAVGSWTG 75 Query: 74 KLSPRLAALK------------PGDEVQVVSEAA--GFFVLDEVPHCETLWMLATGTAIG 119 KL + + PG V + + + + ++ G + Sbjct: 76 KLYQLIREQREEWIRSGSSQSLPGVPVYIDGPYGTPSTHIFES----KYAILICAGIGVT 131 Query: 120 PYLSILQLGKDLD-------RFKNLVLVHAARYAA------DLSYLPLMQELEKRYEGKL 166 P+ SIL+ + K + R +L ++ ++ L Sbjct: 132 PFASILKSILHRNQQNPAKMPLKKVHFYWLNREQKAFEWFVELLSKIEAEDTNNLFDLNL 191 Query: 167 RIQTVVSRETAAGSLTGRIPALIES---------------------GELESTIGLPMNKE 205 + + S L+ E+ + + Sbjct: 192 YLTGAQQKSDMKSSTLFVAMDLMHQETKVDLITGLKSRTKTGRPDWEEIFKDVAKQHAPD 251 Query: 206 TSHVMLCGNPQM 217 V CG + Sbjct: 252 NVEVFFCGPTGL 263 >1EP2-B nrPDB Length = 261 Score = 45.5 bits (106), Expect = 2e-05, Method: Composition-based stats. Identities = 28/194 (14%), Positives = 66/194 (34%), Gaps = 24/194 (12%) Query: 33 AGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPR---LAALKPGDEVQ 89 GQF L + ++R S + + + + G + L+ L+ G +V Sbjct: 35 PGQFLHLAVPNGAMLLRRPISISS--WDKRAKTCTILYRIGDETTGTYKLSKLESGAKVD 92 Query: 90 VVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADL 149 V+ F + EV + + ++ G + P + + + ++L A+ L Sbjct: 93 VMGPLGNGFPVAEVTSTDKILIIGGGIGVPPLYELAKQLEKTGCQMTILLGFASENVKIL 152 Query: 150 SYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELESTIGLPMNKETSHV 209 E + + ++ + + G + L+ ++ E + Sbjct: 153 ---------ENEFSNLKNVTLKIATDDGSYGTKGHVGMLMNE----------IDFEVDAL 193 Query: 210 MLCGNPQMVRDTQQ 223 CG P M++ + Sbjct: 194 YTCGAPAMLKAVAK 207 >5JCA-S nrPDB Length = 284 Score = 37.8 bits (86), Expect = 0.005, Method: Composition-based stats. Identities = 29/223 (13%), Positives = 66/223 (29%), Gaps = 26/223 (11%) Query: 7 GKVTKVQNWTDALFSLTVHAPVL--PFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLE 64 K+ + + + + +P + GQF + L GER+ + + D Sbjct: 8 FKILRKERLAPGINLFEIESPRIAKHAKPGQFVMIRLHEKGERI--PLTIAD-VDISKGS 64 Query: 65 FYLVTVPDGKLSPRLAALKPGDEVQ-VVSEAAGFFVLDEVPHCETLWMLATGTAIGPYLS 123 +V GK + L + GD + V+ +D + I P Sbjct: 65 ITIVAQEVGKTTRELGTYEAGDYILDVLGPLGKPSHIDYFGTVVMIGGGVGVAEIYP--- 121 Query: 124 ILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTG 183 + + K+ + ++ + R + + ++ + V+ Sbjct: 122 VAKAMKEKGNY--VISILGFRTKDLVFWEDKLRSVSDE---------VIVTTNDGSYGMK 170 Query: 184 RIPALIESGELESTIGLPMNKETSHVMLCGNPQMVRDTQQLLK 226 +E ++ V G M++ +L K Sbjct: 171 GFTTHALQKLIEE------GRKIDLVHAVGPAIMMKAVAELTK 207 >3NAW-A nrPDB Length = 613 Score = 32.0 bits (71), Expect = 0.24, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 28/83 (33%), Gaps = 3/83 (3%) Query: 138 VLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVVSRETAAGSLTGRIPALIESGELEST 197 ++++ +R +EL + Y ++ V + P + +L Sbjct: 308 IVMNGSRRDG---MQERFRELYEVYLKNEKVYPVTQQSDFGLCDGSGKPDWDDDSDLAYN 364 Query: 198 IGLPMNKETSHVMLCGNPQMVRD 220 L +++ M+C MV Sbjct: 365 WVLLSSQDDGMAMMCSLSHMVDM 387 >4M4Z-A nrPDB Length = 170 Score = 29.3 bits (64), Expect = 1.5, Method: Composition-based stats. Identities = 18/98 (18%), Positives = 35/98 (35%), Gaps = 13/98 (13%) Query: 17 DALFSLTVHAP-VLPFTAGQFTKLGLEIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKL 75 A SL + P + G + + E+ G R Y+ + ++ V G L Sbjct: 25 PAELSLRLGEPLTIVSEDGDWWTVLSEVSG----REYNIPS--------VHVAKVSHGWL 72 Query: 76 SPRLAALKPGDEVQVVSEAAGFFVLDEVPHCETLWMLA 113 L+ K + + + G F++ E + L+ Sbjct: 73 YEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLS 110 >1V5X-A nrPDB Length = 203 Score = 28.9 bits (63), Expect = 2.1, Method: Composition-based stats. Identities = 14/67 (20%), Positives = 25/67 (37%), Gaps = 3/67 (4%) Query: 113 ATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLMQELEKRYEGKLRIQTVV 172 A G A+GP++ + + +D + L L+ AR + E + R V+ Sbjct: 44 AIGEALGPFVVRVGVFRDQPPEEVLRLMEEARLQVAQLHGEEPPEWAEAVG---RFYPVI 100 Query: 173 SRETAAG 179 G Sbjct: 101 KAFPLEG 107 >1TMX-A nrPDB Length = 293 Score = 28.2 bits (61), Expect = 3.5, Method: Composition-based stats. Identities = 22/148 (14%), Positives = 40/148 (27%), Gaps = 16/148 (10%) Query: 42 EIDGERVQRAYSYVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGDEVQVVSEAAG----- 96 + DG V A V D+ FY V D + + R A L + G Sbjct: 142 DTDGNPVPDARIEVWEADDDG--FYDVQYDDDRTAAR-AHL-------LSGPDGGYAFWA 191 Query: 97 -FFVLDEVPHCETLWMLATGTAIGPYLSILQLGKDLDRFKNLVLVHAARYAADLSYLPLM 155 +PH + + T P + + ++ H +L + Sbjct: 192 ITPTPYPIPHDGPVGRMLAATGRSPMRASHLHFMVTAPGRRTLVTHIFVEGDELLDRDSV 251 Query: 156 QELEKRYEGKLRIQTVVSRETAAGSLTG 183 ++ Q + + G Sbjct: 252 FGVKDSLVKSFERQPAGAPTPGGREIDG 279 >4C7Y-A nrPDB Length = 907 Score = 27.4 bits (59), Expect = 5.5, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 30/69 (43%), Gaps = 10/69 (14%) Query: 54 YVNSPDNPDLEFYLVTVPDGKLSPRLAALKPGD--EVQVVSEAAGFFVLDEVPHCETLWM 111 + ++ + +FY+ P + P +A GD + + S++ G + L+M Sbjct: 347 FASADVTVEGDFYVGRQPHMPIEPDVAFAYMGDDGKCYIHSKSIGVHL--------HLYM 398 Query: 112 LATGTAIGP 120 +A G + P Sbjct: 399 IAPGVGLEP 407 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.308 0.128 0.320 Lambda K H 0.267 0.0396 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 8,139,093 Number of Sequences: 36641 Number of extensions: 285290 Number of successful extensions: 1012 Number of sequences better than 10.0: 44 Number of HSP's better than 10.0 without gapping: 46 Number of HSP's successfully gapped in prelim test: 25 Number of HSP's that attempted gapping in prelim test: 858 Number of HSP's gapped (non-prelim): 73 length of query: 248 length of database: 10,336,785 effective HSP length: 95 effective length of query: 153 effective length of database: 6,855,890 effective search space: 1048951170 effective search space used: 1048951170 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 58 (27.0 bits)