BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P28472 (473 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 6HUO-B nrPDB 927 0.0 4COF-A nrPDB 639 0.0 6DW1-E nrPDB 613 e-176 6D6T-A nrPDB 597 e-171 5O8F-A nrPDB 543 e-155 6DW0-D nrPDB 283 1e-76 6HUO-C nrPDB 282 3e-76 5CFB-A nrPDB 281 5e-76 3JAE-A nrPDB 279 2e-75 6D6U-E nrPDB 271 4e-73 6HUJ-A nrPDB 249 2e-66 6A96-A nrPDB 240 1e-63 3RI5-A nrPDB 231 5e-61 6D6T-B nrPDB 231 6e-61 6DW1-C nrPDB 230 8e-61 6D6T-E nrPDB 230 9e-61 4X5T-A nrPDB 170 1e-42 6CDU-A nrPDB 135 3e-32 2M6B-A nrPDB 127 1e-29 5OSB-A nrPDB 125 3e-29 4YEU-A nrPDB 93 3e-19 2YKS-A nrPDB 91 1e-18 6HIS-A nrPDB 82 4e-16 3TLU-A nrPDB 82 5e-16 2BG9-B nrPDB 81 8e-16 4BOT-B nrPDB 77 2e-14 1VRY-A nrPDB 76 3e-14 6FL9-A nrPDB 75 7e-14 6CNK-A nrPDB 68 8e-12 5KXI-B nrPDB 67 2e-11 2BG9-C nrPDB 61 1e-09 4BOG-3 nrPDB 60 2e-09 2BG9-E nrPDB 58 1e-08 4BOG-1 nrPDB 58 1e-08 5FJV-A nrPDB 57 1e-08 2BG9-A nrPDB 56 3e-08 4AQ5-A nrPDB 55 5e-08 4UXU-A nrPDB 51 1e-06 3IGQ-A nrPDB 43 3e-04 2QC1-B nrPDB 37 0.015 4MRS-A nrPDB 31 0.96 4UM3-P nrPDB 31 0.98 2LCK-A nrPDB 31 1.3 3FKD-A nrPDB 30 2.4 5DTU-A nrPDB 30 2.7 5XYI-g nrPDB 29 4.7 >6HUO-B nrPDB Length = 473 Score = 927 bits (2395), Expect = 0.0, Method: Compositional matrix adjust. Identities = 447/448 (99%), Positives = 448/448 (100%) Query: 26 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85 +SVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT Sbjct: 26 RSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85 Query: 86 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP Sbjct: 86 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145 Query: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER Sbjct: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205 Query: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF Sbjct: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265 Query: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA Sbjct: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 Query: 326 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGI 385 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGI Sbjct: 326 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGI 385 Query: 386 GDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDV 445 GDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDV Sbjct: 386 GDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDV 445 Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 NAIDRWSRIVFPFTFSLFNLVYWLYYVN Sbjct: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 >4COF-A nrPDB Length = 355 Score = 639 bits (1647), Expect = 0.0, Method: Compositional matrix adjust. Identities = 309/318 (97%), Positives = 311/318 (97%), Gaps = 1/318 (0%) Query: 25 AQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 84 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL Sbjct: 3 GQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 62 Query: 85 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 144 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH Sbjct: 63 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 122 Query: 145 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 204 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE Sbjct: 123 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 182 Query: 205 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 264 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS Sbjct: 183 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 242 Query: 265 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 324 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY Sbjct: 243 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 302 Query: 325 AFVNYIFFGRGPQRQKKL 342 AFVNYIFF + P R + Sbjct: 303 AFVNYIFFSQ-PARAAAI 319 Score = 62.0 bits (149), Expect = 6e-10, Method: Compositional matrix adjust. Identities = 27/27 (100%), Positives = 27/27 (100%) Query: 447 AIDRWSRIVFPFTFSLFNLVYWLYYVN 473 AIDRWSRIVFPFTFSLFNLVYWLYYVN Sbjct: 318 AIDRWSRIVFPFTFSLFNLVYWLYYVN 344 >6DW1-E nrPDB Length = 384 Score = 613 bits (1581), Expect = e-176, Method: Compositional matrix adjust. Identities = 292/333 (87%), Positives = 311/333 (93%) Query: 1 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP 60 MW + G+ S PV+VA+VCCA S N+P NMS+VKETVD+LLKGYDIRLRPDFGGPP Sbjct: 1 MWTVQNRESLGLLSFPVMVAMVCCAHSSNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP 60 Query: 61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD 120 V VGM ID+ASIDMVSEVNMDYTLTMYFQQ W+DKRL+YSGIPLNLTLDNRVADQLWVPD Sbjct: 61 VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD 120 Query: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE Sbjct: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180 Query: 181 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK 240 SYGYTTDDIEFYW GG+ AVTGV +IELPQFSIV++++VS+ V F TGAYPRLSLSFRLK Sbjct: 181 SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK 240 Query: 241 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 300 RNIGYFILQTYMPS LITILSWVSFWINYDASAARVALGITTVLTMTTI+THLRETLPKI Sbjct: 241 RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI 300 Query: 301 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFG 333 PYVKAID+YLMGCFVFVFLALLEYAFVNYIFFG Sbjct: 301 PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFG 333 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 28/35 (80%), Positives = 33/35 (94%) Query: 439 IPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 IPDLTDVN+ID+WSR+ FP TFSLFN+VYWLYYV+ Sbjct: 336 IPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 370 >6D6T-A nrPDB Length = 341 Score = 597 bits (1539), Expect = e-171, Method: Compositional matrix adjust. Identities = 285/317 (89%), Positives = 301/317 (94%), Gaps = 1/317 (0%) Query: 26 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85 QSVNDP NMS VKETVD+LLKGYDIRLRPDFGGPPV VGMNIDIASIDMVSEVNMDYTLT Sbjct: 1 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLT 60 Query: 86 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145 MYFQQ WRDKRL+Y+ IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP Sbjct: 61 MYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 120 Query: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRG D AVTGV + Sbjct: 121 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTK 180 Query: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265 IELPQFSIV+++L+++ VVF+TG+YPRLSLSF+LKRNIGYFILQTYMPSILITILSWVSF Sbjct: 181 IELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSF 240 Query: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVF+ALLEYA Sbjct: 241 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYA 300 Query: 326 FVNYIFFGRGPQRQKKL 342 VNYIFF + P R + Sbjct: 301 LVNYIFFSQ-PARAAAI 316 Score = 53.1 bits (126), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 22/27 (81%), Positives = 23/27 (85%) Query: 447 AIDRWSRIVFPFTFSLFNLVYWLYYVN 473 AIDRWSRI FP FS FN+VYWLYYVN Sbjct: 315 AIDRWSRIFFPVVFSFFNIVYWLYYVN 341 >5O8F-A nrPDB Length = 367 Score = 543 bits (1398), Expect = e-155, Method: Compositional matrix adjust. Identities = 267/318 (83%), Positives = 286/318 (89%), Gaps = 1/318 (0%) Query: 25 AQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 84 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL Sbjct: 3 GQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 62 Query: 85 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 144 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH Sbjct: 63 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 122 Query: 145 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 204 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE Sbjct: 123 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 182 Query: 205 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 264 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYF++QTY+P I+ ILS VS Sbjct: 183 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFVIQTYLPCIMTVILSQVS 242 Query: 265 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 324 FW+N ++ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+ Sbjct: 243 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 302 Query: 325 AFVNYIFFGRGPQRQKKL 342 A VNY F P R K+ Sbjct: 303 ATVNY-FTKSQPARAAKI 319 Score = 40.0 bits (92), Expect = 0.002, Method: Compositional matrix adjust. Identities = 17/26 (65%), Positives = 19/26 (73%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYYVN 473 ID+ SRIVFP F FNLVYW Y+N Sbjct: 319 IDKMSRIVFPILFGTFNLVYWATYLN 344 >6DW0-D nrPDB Length = 490 Score = 283 bits (724), Expect = 1e-76, Method: Compositional matrix adjust. Identities = 163/436 (37%), Positives = 243/436 (55%), Gaps = 44/436 (10%) Query: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100 ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL ++ Sbjct: 69 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 128 Query: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160 L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A Sbjct: 129 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 188 Query: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220 C + L +P+DE +C LE SYGY ++I + W+ V L QFS V R + Sbjct: 189 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 248 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI Sbjct: 249 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 308 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P + K Sbjct: 309 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 368 Query: 341 KLAEKTAKAKND-RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSA---ISFD 396 +K D R +S + +++ T L+ +E E D ++ A F+ Sbjct: 369 DKKKKNPAPTIDIRPRSATIQMNN-----ATHLQERDE--EYGYECLDGKDCASFFCCFE 421 Query: 397 NSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIVF 456 + R G R H + H+R + +D ++RI F Sbjct: 422 DC----------RTGAWR--------HGRIHIR---------------IAKMDSYARIFF 448 Query: 457 PFTFSLFNLVYWLYYV 472 P F LFNLVYW+ Y+ Sbjct: 449 PTAFCLFNLVYWVSYL 464 >6HUO-C nrPDB Length = 495 Score = 282 bits (721), Expect = 3e-76, Method: Compositional matrix adjust. Identities = 161/437 (36%), Positives = 241/437 (55%), Gaps = 38/437 (8%) Query: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100 ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL ++ Sbjct: 70 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 129 Query: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160 L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A Sbjct: 130 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 189 Query: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220 C + L +P+DE +C LE SYGY ++I + W+ V L QFS V R + Sbjct: 190 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 249 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI Sbjct: 250 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 309 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P + K Sbjct: 310 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKPSKDK 369 Query: 341 KLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVH-NEMNEVSG-GIGDTRNSA---ISF 395 +K + K+ + + + + H E +E G D ++ A F Sbjct: 370 DKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASFFCCF 429 Query: 396 DNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSRIV 455 ++ R G R H + H+R + +D ++RI Sbjct: 430 EDC----------RTGAWR--------HGRIHIR---------------IAKMDSYARIF 456 Query: 456 FPFTFSLFNLVYWLYYV 472 FP F LFNLVYW+ Y+ Sbjct: 457 FPTAFCLFNLVYWVSYL 473 >5CFB-A nrPDB Length = 362 Score = 281 bits (718), Expect = 5e-76, Method: Compositional matrix adjust. Identities = 140/297 (47%), Positives = 202/297 (68%), Gaps = 10/297 (3%) Query: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 +DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL Sbjct: 14 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 73 Query: 98 AYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 AYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R+T Sbjct: 74 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 133 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 T +C MDL+ +P+D Q C +++ES+GYT +D+ F W+ + V E + LPQF + E Sbjct: 134 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQD-EAPVQVAEGLTLPQFLLKEE 192 Query: 217 ---RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASA 273 R +++ + TG + + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ Sbjct: 193 KDLRYCTKH--YNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAP 250 Query: 274 ARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 ARVALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++ Sbjct: 251 ARVALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFV 307 Score = 30.4 bits (67), Expect = 1.6, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 15/24 (62%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYY 471 ID SR FP F +FN+ YW+ Y Sbjct: 322 IDTISRACFPLAFLIFNIFYWVIY 345 >3JAE-A nrPDB Length = 342 Score = 279 bits (713), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 142/299 (47%), Positives = 199/299 (66%), Gaps = 10/299 (3%) Query: 39 ETVDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDK 95 E +DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D Sbjct: 4 EFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWNDP 63 Query: 96 RLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLR 154 RLAYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R Sbjct: 64 RLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSIR 123 Query: 155 ITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIV 214 IT AC MDL+ +P+D Q C +++ES+GYT +D+ F W AV + + LPQF + Sbjct: 124 ITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEW-DEKGAVQVADGLTLPQFILK 182 Query: 215 EH---RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDA 271 E R +++ + TG + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA Sbjct: 183 EEKDLRYCTKH--YNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDA 240 Query: 272 SAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + ARV LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN+I Sbjct: 241 APARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFI 299 Score = 32.0 bits (71), Expect = 0.53, Method: Compositional matrix adjust. Identities = 12/24 (50%), Positives = 16/24 (66%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYY 471 ID SR+ FP F +FN+ YW+ Y Sbjct: 314 IDTVSRVAFPLVFLIFNIFYWITY 337 >6D6U-E nrPDB Length = 394 Score = 271 bits (694), Expect = 4e-73, Method: Compositional matrix adjust. Identities = 133/302 (44%), Positives = 193/302 (63%), Gaps = 1/302 (0%) Query: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100 ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL ++ Sbjct: 68 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 127 Query: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160 L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A Sbjct: 128 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 187 Query: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220 C + L +P+DE +C LE SYGY ++I + W+ V L QFS V R + Sbjct: 188 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 247 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI Sbjct: 248 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 307 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y F P R Sbjct: 308 TTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHY-FVSSQPARAA 366 Query: 341 KL 342 K+ Sbjct: 367 KM 368 Score = 35.0 bits (79), Expect = 0.079, Method: Compositional matrix adjust. Identities = 14/25 (56%), Positives = 19/25 (76%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYYV 472 +D ++RI FP F LFNLVYW+ Y+ Sbjct: 368 MDSYARIFFPTAFCLFNLVYWVSYL 392 >6HUJ-A nrPDB Length = 464 Score = 249 bits (636), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 156/454 (34%), Positives = 235/454 (51%), Gaps = 60/454 (13%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 46 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 105 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 106 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 165 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 166 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 225 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 226 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 285 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 286 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 344 Query: 331 FFGRG---------PQRQKKLAEKTAKAKNDRSKSESNRVD--AHGNILLTSLEVHNEMN 379 F RG P++ KK+ + K N + + ++ A G+ L ++ Sbjct: 345 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATI------- 397 Query: 380 EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKI 439 A S + + ++ P E F Sbjct: 398 ------------AKSATIEPKEVKPETKPPEPKKTF------------------------ 421 Query: 440 PDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 V+ IDR SRI FP F +FNLVYW Y+N Sbjct: 422 ---NSVSKIDRLSRIAFPLLFGIFNLVYWATYLN 452 >6A96-A nrPDB Length = 392 Score = 240 bits (612), Expect = 1e-63, Method: Compositional matrix adjust. Identities = 126/312 (40%), Positives = 188/312 (60%), Gaps = 3/312 (0%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N++ +D LL GYD RLRP G V +I + S VS+ M+YT+ ++F+Q W Sbjct: 45 NITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSW 104 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL DGT+LY Sbjct: 105 KDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYT 164 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD--KAVTGVERIELPQ 210 +R+T +A C M L +P+D C L+ SY Y ++ + W G V + L Q Sbjct: 165 MRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQ 224 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + + N+ +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 225 YHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 284 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 285 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 343 Query: 331 FFGRGPQRQKKL 342 F P R K+ Sbjct: 344 FTKSQPARAAKI 355 Score = 39.7 bits (91), Expect = 0.003, Method: Compositional matrix adjust. Identities = 17/26 (65%), Positives = 19/26 (73%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYYVN 473 ID+ SRIVFP F FNLVYW Y+N Sbjct: 355 IDKMSRIVFPVLFGTFNLVYWATYLN 380 >3RI5-A nrPDB Length = 347 Score = 231 bits (589), Expect = 5e-61, Method: Compositional matrix adjust. Identities = 120/292 (41%), Positives = 177/292 (60%), Gaps = 10/292 (3%) Query: 46 KGYDIRLRP--DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS--- 100 GYD R+RP D GGP V V +N+ + +I + VNM+Y+ + ++ W DKRL+Y Sbjct: 12 SGYDFRVRPPTDNGGP-VVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDKRLSYGVKG 70 Query: 101 -GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTA 159 G P + L V Q+W+PDT+F N+K+++ H + N +IR+H DGTVLY +RI+ Sbjct: 71 DGQPDFVIL--TVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLYSVRISLVL 128 Query: 160 ACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE-RIELPQFSIVEHRL 218 +C M L+ YP+D Q C++++ SY YTT DIE+ W+ V LP F + Sbjct: 129 SCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPSFQLTNTST 188 Query: 219 VSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVAL 278 V TG Y L + +LKR +++LQ Y+PS ++ I+SWVSFW + A ARV L Sbjct: 189 TYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRTAIPARVTL 248 Query: 279 GITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 G+TT+LTMT + + LP + Y+KAID+++ C F+F ALLE+A VN+I Sbjct: 249 GVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHI 300 >6D6T-B nrPDB Length = 358 Score = 231 bits (588), Expect = 6e-61, Method: Compositional matrix adjust. Identities = 126/312 (40%), Positives = 188/312 (60%), Gaps = 3/312 (0%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 11 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 70 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 71 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 130 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 131 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 190 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 191 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 250 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 251 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 309 Query: 331 FFGRGPQRQKKL 342 F P R K+ Sbjct: 310 FTKSQPARAAKI 321 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 17/26 (65%), Positives = 19/26 (73%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYYVN 473 IDR SRI FP F +FNLVYW Y+N Sbjct: 321 IDRLSRIAFPLLFGIFNLVYWATYLN 346 >6DW1-C nrPDB Length = 402 Score = 230 bits (587), Expect = 8e-61, Method: Compositional matrix adjust. Identities = 125/308 (40%), Positives = 188/308 (61%), Gaps = 3/308 (0%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 37 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 96 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 97 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 156 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 157 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 216 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 217 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 276 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 277 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 335 Query: 331 FFGRGPQR 338 F RG ++ Sbjct: 336 FTKRGTKK 343 Score = 42.4 bits (98), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 18/29 (62%), Positives = 21/29 (72%) Query: 445 VNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 V+ IDR SRI FP F +FNLVYW Y+N Sbjct: 348 VSKIDRLSRIAFPLLFGIFNLVYWATYLN 376 >6D6T-E nrPDB Length = 366 Score = 230 bits (587), Expect = 9e-61, Method: Compositional matrix adjust. Identities = 113/257 (43%), Positives = 163/257 (63%) Query: 41 VDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYS 100 ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+RL ++ Sbjct: 68 LNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRRLKFN 127 Query: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160 L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T A Sbjct: 128 STIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLTIDAE 187 Query: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220 C + L +P+DE +C LE SYGY ++I + W+ V L QFS V R + Sbjct: 188 CQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGLRNTT 247 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR +LGI Sbjct: 248 EVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPARTSLGI 307 Query: 281 TTVLTMTTINTHLRETL 297 TTVLTMTT++T R++L Sbjct: 308 TTVLTMTTLSTIARKSL 324 >4X5T-A nrPDB Length = 330 Score = 170 bits (431), Expect = 1e-42, Method: Compositional matrix adjust. Identities = 105/302 (34%), Positives = 158/302 (52%), Gaps = 30/302 (9%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 8 PPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 67 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RR+P+D Q Sbjct: 68 EAIWIPEIRFVNVENARDADVV----DISVSPDGTVQYLERFSARVLSPLDFRRFPMDSQ 123 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 124 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 181 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 + L R+ R +GY+++Q Y+PS+LI ILSW+SFWIN DA+ ARV LGI Sbjct: 182 K-----------LDYQLRISRQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGI 230 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++ PQR K Sbjct: 231 TTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQSQPQRAK 290 Query: 341 KL 342 K+ Sbjct: 291 KI 292 Score = 33.1 bits (74), Expect = 0.27, Method: Compositional matrix adjust. Identities = 13/24 (54%), Positives = 17/24 (70%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYY 471 ID+ SRI FP F +FN+ YW+ Y Sbjct: 292 IDKISRIGFPMAFLIFNMFYWIIY 315 >6CDU-A nrPDB Length = 324 Score = 135 bits (340), Expect = 3e-32, Method: Compositional matrix adjust. Identities = 100/304 (32%), Positives = 146/304 (48%), Gaps = 36/304 (11%) Query: 60 PVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG----IPLNLTLDNRVADQ 115 PV V ++I I I V+ + Y + Y W K G I N ++ + + Sbjct: 11 PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNG 70 Query: 116 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC 175 LWVP F+N V N+ + L PDG V+Y R + + MD R +P D Q Sbjct: 71 LWVPALEFIN----VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQF 126 Query: 176 TLEIESYGYTTDDIEF-----------------YWRGGDKAVTGVERIELPQFSIVEHRL 218 LE+E + Y + F +W G KA T + I S V+ Sbjct: 127 VLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRG-KASTHISDIRYDHLSSVQPN- 184 Query: 219 VSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVAL 278 + R+++ R IGYF++QTY+P I+ ILS VSFW+N ++ AR Sbjct: 185 --------QNEFSRITVRIDAVRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVF 236 Query: 279 GITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQR 338 G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY F RG + Sbjct: 237 GVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY-FTKRGVES 295 Query: 339 QKKL 342 K+ Sbjct: 296 VSKI 299 Score = 41.2 bits (95), Expect = 0.001, Method: Compositional matrix adjust. Identities = 18/32 (56%), Positives = 22/32 (68%) Query: 442 LTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 + V+ IDR SRI FP F +FNLVYW Y+N Sbjct: 293 VESVSKIDRLSRIAFPLLFGIFNLVYWATYLN 324 >2M6B-A nrPDB Length = 150 Score = 127 bits (319), Expect = 1e-29, Method: Composition-based stats. Identities = 64/110 (58%), Positives = 84/110 (76%), Gaps = 6/110 (5%) Query: 239 LKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLP 298 L+R +GY+++Q Y+PS+LI ILSW+SFWIN DA+ ARV LGITTVLT+TT ++ R +LP Sbjct: 2 LERQLGYYLIQLYIPSLLIVILSWISFWINLDAAPARVGLGITTVLTLTTQSSGSRASLP 61 Query: 299 KIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIF----FGRGP--QRQKKL 342 K+ YVKAID++L C +FVF ALLEYA VN++ FG G QR KK+ Sbjct: 62 KVSYVKAIDIWLAVCLLFVFSALLEYAAVNFVSRQREFGGGGFIQRAKKI 111 Score = 35.8 bits (81), Expect = 0.039, Method: Composition-based stats. Identities = 14/24 (58%), Positives = 17/24 (70%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYY 471 ID+ SRI FP F +FNL YW+ Y Sbjct: 111 IDKISRIGFPLAFLIFNLFYWIIY 134 >5OSB-A nrPDB Length = 336 Score = 125 bits (315), Expect = 3e-29, Method: Compositional matrix adjust. Identities = 94/302 (31%), Positives = 145/302 (48%), Gaps = 31/302 (10%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 8 PPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 67 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RRYP D Q Sbjct: 68 EAIWIPEIRFVNVENARDADVV----DISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ 123 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 124 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 181 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 + L R+ R GYF++QTY+P I+ ILS VSFW+N ++ AR + Sbjct: 182 K-----------LDYQLRISRQYGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFVV 230 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY F P R Sbjct: 231 TTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY-FTKSQPARAA 289 Query: 341 KL 342 K+ Sbjct: 290 KI 291 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 17/26 (65%), Positives = 19/26 (73%) Query: 448 IDRWSRIVFPFTFSLFNLVYWLYYVN 473 IDR SRI FP F +FNLVYW Y+N Sbjct: 291 IDRLSRIAFPLLFGIFNLVYWATYLN 316 >4YEU-A nrPDB Length = 312 Score = 92.8 bits (229), Expect = 3e-19, Method: Compositional matrix adjust. Identities = 77/310 (24%), Positives = 124/310 (40%), Gaps = 35/310 (11%) Query: 60 PVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG----IPLNLTLDNRVADQ 115 PV V ++I I I V+ + Y + Y W K G I N ++ + + Sbjct: 1 PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNG 60 Query: 116 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC 175 LWVP F+N V N+ + L PDG V+Y R + + MD R +P D Q Sbjct: 61 LWVPALEFIN----VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQF 116 Query: 176 TLEIESYGYTTD-----DIEFY-----------WRGGDKAVTGVERIELPQFSIVEHRLV 219 LE+E + Y DI+ Y W KA T + I S V+ Sbjct: 117 VLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPN-- 174 Query: 220 SRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALG 279 + R+++ RN +I +P + I +SW +FW + A V L Sbjct: 175 -------QNEFSRITVRIDAVRNYFSYIPNIILPMLFILFISWTAFW--STSYEANVTLV 225 Query: 280 ITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQ 339 ++T++ N + LPK PY+ + ++F F+A++E +Y+ P R Sbjct: 226 VSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARA 285 Query: 340 KKLAEKTAKA 349 + + A Sbjct: 286 ASITRASRIA 295 >2YKS-A nrPDB Length = 321 Score = 90.9 bits (224), Expect = 1e-18, Method: Compositional matrix adjust. Identities = 74/289 (25%), Positives = 119/289 (41%), Gaps = 34/289 (11%) Query: 60 PVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG----IPLNLTLDNRVADQ 115 PV V ++I I I V+ + Y + Y W K G I N ++ + + Sbjct: 11 PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNG 70 Query: 116 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC 175 LWVP F+N V N+ + L PDG V+Y R + + MD R +P D Q Sbjct: 71 LWVPALEFIN----VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQF 126 Query: 176 TLEIESYGYTTD-----DIEFYWRGGD----------KAVTGVERIELPQFSIVEHRLVS 220 LE+E + Y DI+ Y D KA T + I S V+ Sbjct: 127 VLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRKASTHISDIRYDHLSSVQPN--- 183 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 + R+++ RN Y++ +P LI SW FW+ ++ + R+ Sbjct: 184 ------QNEFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWL--ESFSERLQTSF 235 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNY 329 T +LT+ + LP++PY ID ++ + +F A+L F ++ Sbjct: 236 TLMLTVVAYAAYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHH 284 >6HIS-A nrPDB Length = 445 Score = 82.0 bits (201), Expect = 4e-16, Method: Compositional matrix adjust. Identities = 83/313 (26%), Positives = 138/313 (44%), Gaps = 33/313 (10%) Query: 42 DKLLKGYDIRLRP--DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY 99 D LL Y +RP D+ P V +++ + +I V E N T ++++QYW D+ L + Sbjct: 10 DHLLANYKKGVRPVRDWRKP-TTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFLQW 68 Query: 100 SGIPL-NLTLDNRVADQLWVPDTYFLNDKKSFVH-GVTVKNRMIRLHPDGTVLYGLRITT 157 + N+T + D +WVPD FV G + + +H G V + Sbjct: 69 TPEDFDNVTKLSIPTDSIWVPDILI----NEFVDVGKSPNIPYVYVHHRGEVQNYKPLQL 124 Query: 158 TAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF-YWRG-----GDKAV----TGVERIE 207 AC +D+ +P D QNC+L S+ +T DI WR DK++ E +E Sbjct: 125 VTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELLE 184 Query: 208 L-PQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFW 266 + PQF + + +Y + ++R ++ + +PSI + ++ V F Sbjct: 185 VFPQF--------KEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFC 236 Query: 267 INYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAF 326 + D S RV+ IT +L + + +TLP AI L+G + V +ALL + Sbjct: 237 LPPD-SGERVSFKITLLLGYSVFLIIVSDTLPA----TAIGTPLIGVYFVVCMALLVISL 291 Query: 327 VNYIFFGRGPQRQ 339 IF R +Q Sbjct: 292 AETIFIVRLVHKQ 304 >3TLU-A nrPDB Length = 321 Score = 82.0 bits (201), Expect = 5e-16, Method: Compositional matrix adjust. Identities = 70/307 (22%), Positives = 126/307 (41%), Gaps = 34/307 (11%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 13 PPIADEPLTVNTGIYLIESYSLDDCAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 72 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RRYP D Q Sbjct: 73 EAIWIPEIRFVNVENARDADVV----DISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ 128 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 129 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 186 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFW-INYDASAARVALG 279 +L R+ R +I +P + I +SW +FW +Y+A+ V L Sbjct: 187 -----------KLDYQLRISRQYFSYIPNIILPMLFILFISWTAFWSTSYEAN---VTLV 232 Query: 280 ITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQ 339 ++T++ N + LP PY+ + ++F F+A++E +Y+ P R Sbjct: 233 VSTLIAHIAFNILVETNLPCTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARA 292 Query: 340 KKLAEKT 346 + + Sbjct: 293 ASITRAS 299 >2BG9-B nrPDB Length = 370 Score = 81.3 bits (199), Expect = 8e-16, Method: Compositional matrix adjust. Identities = 84/323 (26%), Positives = 153/323 (47%), Gaps = 21/323 (6%) Query: 44 LLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL----- 97 L + Y+ ++RP G V V + + + S+ +++E N + T +++ W D RL Sbjct: 11 LFENYNPKVRPSQTVGDKVTVRVGLTLTSLLILNEKNEEMTTSVFLNLAWTDYRLQWDPA 70 Query: 98 AYSGIPLNLTLDNRVADQLWVPDTYFLNDKK-SFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 AY GI +L++ +D +W PD +N+ SF +T+ ++ H G V + Sbjct: 71 AYEGIK-DLSIP---SDDVWQPDIVLMNNNDGSF--EITLHVNVLVQH-TGAVSWHPSAI 123 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 ++C + + +P D QNCT+ +SY Y T ++ D + E Q+SI EH Sbjct: 124 YRSSCTIKVMYFPFDWQNCTMVFKSYTYDTSEV-ILQHALDAMINQDAFTENGQWSI-EH 181 Query: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276 + +N +Y ++ ++R ++I+ T +P ILI+IL+ + F++ DA ++ Sbjct: 182 KPSRKNWRSDDPSYEDVTFYLIIQRKPLFYIVYTIVPCILISILAILVFYLPPDA-GEKM 240 Query: 277 ALGITTVLTMTTINTHLRETLPKIPY-VKAIDMYLMGCFVFV-FLALLEYAFVNYIFFGR 334 +L I+ +L +T L + +P+ V I YLM + V F +L +N R Sbjct: 241 SLSISALLALTVFLLLLADKVPETSLSVPIIISYLMFIMILVAFSVILSVVVLN--LHHR 298 Query: 335 GPQRQKKLAEKTAKAKNDRSKSE 357 P + + A+ S SE Sbjct: 299 SPNTHEAVEAIKYIAEQLESASE 321 >4BOT-B nrPDB Length = 493 Score = 77.0 bits (188), Expect = 2e-14, Method: Compositional matrix adjust. Identities = 74/294 (25%), Positives = 143/294 (48%), Gaps = 23/294 (7%) Query: 44 LLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL----- 97 L + Y+ ++RP G V V + + + S+ +++E N + T +++ W D RL Sbjct: 35 LFENYNPKVRPSQTVGDKVTVRVGLTLTSLLILNEKNEEMTTSVFLNLAWTDYRLQWDPA 94 Query: 98 AYSGIPLNLTLDNRVADQLWVPDTYFLNDKK-SFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 AY GI +L++ +D +W PD +N+ SF +T+ ++ H G V + Sbjct: 95 AYEGIK-DLSIP---SDDVWQPDIVLMNNNDGSF--EITLHVNVLVQH-TGAVSWHPSAI 147 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSI--- 213 ++C + + +P D QNCT+ +SY Y T ++ K V+ I + Q + Sbjct: 148 YRSSCTIKVMYFPFDWQNCTMVFKSYTYDTSEVILQHALDAKGEREVKEIMINQDAFTEN 207 Query: 214 ----VEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINY 269 +EH+ +N +Y ++ ++R ++I+ T +P ILI+IL+ + F++ Sbjct: 208 GQWSIEHKPSRKNWRSDDPSYEDVTFYLIIQRKPLFYIVYTIVPCILISILAILVFYLPP 267 Query: 270 DASAARVALGITTVLTMTTINTHLRETLPKIPY-VKAIDMYLMGCFVFVFLALL 322 DA +++L I+ +L +T L + +P+ V I YLM + V +++ Sbjct: 268 DA-GEKMSLSISALLALTVFLLLLADKVPETSLSVPIIISYLMFIMILVAFSVI 320 >1VRY-A nrPDB Length = 76 Score = 75.9 bits (185), Expect = 3e-14, Method: Composition-based stats. Identities = 36/57 (63%), Positives = 46/57 (80%) Query: 274 ARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 ARV LGITTVLT+TT ++ R +LPK+ YVKAID++L C +FVF ALLEYA VN++ Sbjct: 3 ARVGLGITTVLTLTTQSSGSRASLPKVSYVKAIDIWLAVCLLFVFSALLEYAAVNFV 59 >6FL9-A nrPDB Length = 320 Score = 75.1 bits (183), Expect = 7e-14, Method: Compositional matrix adjust. Identities = 67/276 (24%), Positives = 124/276 (44%), Gaps = 28/276 (10%) Query: 61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIP---------LNLTLDNR 111 V +G+ ID I +++ ++++ + WR LA+ P L L Sbjct: 11 VFIGLKID--QITGINQKEENFSVVGSLRIDWRQPLLAFEHAPGEPKHRTYTLATFLKLL 68 Query: 112 VADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTT-AACMMDLRRYPL 170 Q+ P + N + + +NR+I L DGTV+Y R T+T A D R +P Sbjct: 69 EEKQIRWPAFTYHNQQGR----MDFQNRLISLSEDGTVMYLERFTSTFQAPAFDFRLFPF 124 Query: 171 DEQNCTLEIES----YGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFA 226 D Q + ++S + + +++ + GD+ G E + + V L + N F Sbjct: 125 DNQLFFIHVDSIFPQHLFRFQEMQGFSGLGDQ--LGEEEWIVTE---VNTHLTTHNE-FT 178 Query: 227 TGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTM 286 G R L F +R++ Y++++ +P +LI +SW +F++ R+ L +L Sbjct: 179 KGDASRFVLEFHAERHLNYYLMRILIPVLLIITVSWFTFFLQ--DYTKRIDLAGGNLLLF 236 Query: 287 TTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALL 322 N + LP++ Y+ +D +L+G F+ L +L Sbjct: 237 IAFNFTISSDLPRLGYITLMDAFLVGTFIITALVVL 272 >6CNK-A nrPDB Length = 386 Score = 68.2 bits (165), Expect = 8e-12, Method: Compositional matrix adjust. Identities = 70/290 (24%), Positives = 128/290 (44%), Gaps = 10/290 (3%) Query: 43 KLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG 101 KL GY+ RP V V + IA + V E N T ++ +Q W D +L + Sbjct: 17 KLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVKQEWHDYKLRWDP 76 Query: 102 IPLNLTLDNRVADQL-WVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160 R+ +L W PD N+ VT + H DG V + ++ Sbjct: 77 ADYENVTSIRIPSELIWRPDIVLYNNADG-DFAVTHLTKAHLFH-DGRVQWTPPAIYKSS 134 Query: 161 CMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH--RL 218 C +D+ +P D+QNCT++ S+ Y I+ V ++ E ++ IV+ Sbjct: 135 CSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV--NMHSRVDQLDFWESGEWVIVDAVGTY 192 Query: 219 VSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVAL 278 +R YP ++ +F ++R ++ + +P +LI+ L+ + F++ + ++ L Sbjct: 193 NTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFYLPSEC-GEKITL 251 Query: 279 GITTVLTMTTINTHLRETLPKIPYV-KAIDMYLMGCFVFVFLALLEYAFV 327 I+ +L++T + E +P V I YL+ +FV L+++ FV Sbjct: 252 CISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITVFV 301 >5KXI-B nrPDB Length = 403 Score = 67.0 bits (162), Expect = 2e-11, Method: Compositional matrix adjust. Identities = 62/290 (21%), Positives = 129/290 (44%), Gaps = 22/290 (7%) Query: 48 YDIRLRPDFGGPP-VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNL 106 Y+ +RP G V V + + +A + V E T ++ Q W D RL + + Sbjct: 17 YNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWEDYRLTWKPEEFDN 76 Query: 107 TLDNRV-ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDL 165 R+ + +W+PD N+ N ++ DG++ + +AC +++ Sbjct: 77 MKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSY--DGSIFWLPPAIYKSACKIEV 134 Query: 166 RRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIV-EHRLVS---- 220 + +P D+QNCT++ S+ Y +I+ V E L F+ E +V+ Sbjct: 135 KHFPFDQQNCTMKFRSWTYDRTEIDL--------VLKSEVASLDDFTPSGEWDIVALPGR 186 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 RN Y ++ F ++R ++ + +P +LIT L+ + F++ D ++ L I Sbjct: 187 RNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDC-GEKMTLCI 245 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + +L +T + + +P ++D+ L+G ++ + L+ ++ V + Sbjct: 246 SVLLALTVFLLLISKIVPP----TSLDVPLVGKYLMFTMVLVTFSIVTSV 291 >2BG9-C nrPDB Length = 369 Score = 60.8 bits (146), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 54/291 (18%), Positives = 133/291 (45%), Gaps = 19/291 (6%) Query: 44 LLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGI 102 ++ Y+ +RP V + +++ ++++ + E + T ++ W D RL ++ Sbjct: 13 IVNKYNKHVRPVKHNNEVVNIALSLTLSNLISLKETDETLTTNVWMDHAWYDHRLTWNAS 72 Query: 103 PL-NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 161 ++++ + +W+PD N+ + N ++R P+G V + ++C Sbjct: 73 EYSDISILRLRPELIWIPDIVLQNNNDGQYNVAYFCNVLVR--PNGYVTWLPPAIFRSSC 130 Query: 162 MMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSR 221 +++ +P D QNC+L+ + Y ++I +A T E ++ I+ H+ + Sbjct: 131 PINVLYFPFDWQNCSLKFTALNYNANEISMDLIIDPEAFT-----ENGEWEII-HKPAKK 184 Query: 222 NVV---FATGA-YPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVA 277 N+ F G Y ++ ++R ++++ P +LI+ L+ ++F++ + S +++ Sbjct: 185 NIYGDKFPNGTNYQDVTFYLIIRRKPLFYVINFITPCVLISFLAALAFYLPAE-SGEKMS 243 Query: 278 LGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVN 328 I +L + LP+ A+ + L+G ++ ++L+ VN Sbjct: 244 TAICVLLAQAVFLLLTSQRLPE----TALAVPLIGKYLMFIMSLVTGVVVN 290 >4BOG-3 nrPDB Length = 505 Score = 60.1 bits (144), Expect = 2e-09, Method: Compositional matrix adjust. Identities = 65/316 (20%), Positives = 130/316 (41%), Gaps = 35/316 (11%) Query: 18 LVAVVCCAQSV--NDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVC-VGMNIDIASIDM 74 L+ ++C A V N+ G + ++KLL YD R++P V V + + + ++ Sbjct: 5 LLLIICLALEVRSNEEGRL------IEKLLGDYDKRIKPAKTLDHVIDVTLKLTLTNLIS 58 Query: 75 VSEVNMDYTLTMYFQQYWRDKRLA-----YSGIPLNLTLDNRVADQL-WVPDTYFLNDKK 128 ++E T ++ + W D RL+ Y GI L R+ +L W+PD N+ Sbjct: 59 LNEKEEALTTNVWIEIQWNDYRLSWNTSEYEGIDLV-----RIPSELLWLPDVVLENNVD 113 Query: 129 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 188 N ++ + DG++ + + C + + +P D QNC+L S Y + Sbjct: 114 GQFEVAYYANVLV--YNDGSMYWLPPAIYRSTCPIAVTYFPFDWQNCSLVFRSQTYNAHE 171 Query: 189 IEFYWRGGDKAVTGVERIELPQFS-----IVEHRLVSRNVVFATGA----YPRLSLSFRL 239 + + V I+ F+ + HR +N + + + + Sbjct: 172 VNLQLSAEEGEVVEWIHIDPEDFTENGEWTIRHRPAKKNYNWQLTKDDIDFQEIIFFLII 231 Query: 240 KRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTT----INTHLRE 295 +R ++I+ P +LI+ L + +++ A + L I+ +L T I + E Sbjct: 232 QRKPLFYIINIIAPCVLISSLVVLVYFLPAQAGGQKCTLSISVLLAQTIFLFLIAQKVPE 291 Query: 296 TLPKIPYVKAIDMYLM 311 T +P + +++M Sbjct: 292 TSLNVPLIGKYLIFVM 307 >2BG9-E nrPDB Length = 370 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 69/341 (20%), Positives = 137/341 (40%), Gaps = 33/341 (9%) Query: 41 VDKLLKGYDIRLRPDFGGPPVC-VGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLA- 98 ++KLL YD R++P V V + + + ++ ++E T ++ + W D RL+ Sbjct: 7 IEKLLGDYDKRIKPAKTLDHVIDVTLKLTLTNLISLNEKEEALTTNVWIEIQWNDYRLSW 66 Query: 99 ----YSGIPLNLTLDNRVADQL-WVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGL 153 Y GI L R+ +L W+PD N+ N ++ + DG++ + Sbjct: 67 NTSEYEGIDLV-----RIPSELLWLPDVVLENNVDGQFEVAYYANVLV--YNDGSMYWLP 119 Query: 154 RITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSI 213 + C + + +P D QNC+L S Y ++ ++ + + E +++I Sbjct: 120 PAIYRSTCPIAVTYFPFDWQNCSLVFRSQTYNAHEVNLQ-LSAEEGIDPEDFTENGEWTI 178 Query: 214 VEHRLVSRNVVFATGA----YPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINY 269 HR +N + + + ++R ++I+ P +LI+ L + +++ Sbjct: 179 -RHRPAKKNYNWQLTKDDIDFQEIIFFLIIQRKPLFYIINIIAPCVLISSLVVLVYFLPA 237 Query: 270 DASAARVALGITTVLTMTT----INTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 A + L I+ +L T I + ET +P + +++M FV L ++ Sbjct: 238 QAGGQKCTLSISVLLAQTIFLFLIAQKVPETSLNVPLIGKYLIFVM----FVSLVIVTNC 293 Query: 326 FVNYIFFGRGPQRQK-----KLAEKTAKAKNDRSKSESNRV 361 + R P K+ K +ND N V Sbjct: 294 VIVLNVSLRTPNTHSCVEACNFIAKSTKEQNDSGSENENWV 334 >4BOG-1 nrPDB Length = 522 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 54/300 (18%), Positives = 133/300 (44%), Gaps = 22/300 (7%) Query: 44 LLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGI 102 ++ Y+ +RP V + +++ ++++ + E + T ++ W D RL ++ Sbjct: 34 IVNKYNKHVRPVKHNNEVVNIALSLTLSNLISLKETDETLTTNVWMDHAWYDHRLTWNAS 93 Query: 103 PL-NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAAC 161 ++++ + +W+PD N+ + N ++R P+G V + ++C Sbjct: 94 EYSDISILRLRPELIWIPDIVLQNNNDGQYNVAYFCNVLVR--PNGYVTWLPPAIFRSSC 151 Query: 162 MMDLRRYPLDEQNCTLEIESYGYTTDDI--EFYWRGGDKAVTGVERIELPQFSIVE---- 215 +++ +P D QNC+L+ + Y ++I + D +E I + + E Sbjct: 152 PINVLYFPFDWQNCSLKFTALNYNANEISMDLMTDTIDGKDYPIEWIIIDPEAFTENGEW 211 Query: 216 ---HRLVSRNVV---FATGA-YPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWIN 268 H+ +N+ F G Y ++ ++R ++++ P +LI+ L+ ++F++ Sbjct: 212 EIIHKPAKKNIYGDKFPNGTNYQDVTFYLIIRRKPLFYVINFITPCVLISFLAALAFYLP 271 Query: 269 YDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVN 328 + S +++ I +L + LP+ A+ + L+G ++ ++L+ VN Sbjct: 272 AE-SGEKMSTAICVLLAQAVFLLLTSQRLPE----TALAVPLIGKYLMFIMSLVTGVVVN 326 >5FJV-A nrPDB Length = 213 Score = 57.4 bits (137), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 44/172 (25%), Positives = 75/172 (43%), Gaps = 19/172 (11%) Query: 44 LLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGI 102 L +GY+ RP V V + IA + V E N T ++ +Q W D +L ++ Sbjct: 8 LFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKLRWNPT 67 Query: 103 PL-NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH--PDGTVLYGLRITTTA 159 N+T ++ +W+PD N+ G M + H GTV + + Sbjct: 68 DFGNITSLRVPSEMIWIPDIVLYNN----ADGEFAVTHMTKAHLFSTGTVHWVPPAIYKS 123 Query: 160 ACMMDLRRYPLDEQNCTLEIESYGY-----------TTDDIEFYWRGGDKAV 200 +C +D+ +P D+QNC ++ S+ Y T D++ YW G+ A+ Sbjct: 124 SCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDLEQMEQTVDLKDYWESGEWAI 175 >2BG9-A nrPDB Length = 370 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 68/330 (20%), Positives = 142/330 (43%), Gaps = 22/330 (6%) Query: 41 VDKLLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY 99 V LL+ Y+ +RP + V + + + + + V EVN + +Q W D RL + Sbjct: 8 VANLLENYNKVIRPVEHHTHFVDITVGLQLIQLINVDEVNQIVETNVRLRQQWIDVRLRW 67 Query: 100 SGIPLNLTLDNRV-ADQLWVPDTYFLNDKK---SFVHGVTVKNRMIRLHPD--GTVLYGL 153 + R+ +D +W+PD N+ + VH M +L D G +++ Sbjct: 68 NPADYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIVH-------MTKLLLDYTGKIMWTP 120 Query: 154 RITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSI 213 + C + + +P D+QNCT+++ + Y + ++ +E ++ + Sbjct: 121 PAIFKSYCEIIVTHFPFDQQNCTMKLGIWTYDGTKVSISPESDRPDLSTF--MESGEWVM 178 Query: 214 VEHRLVSRNVVFAT---GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 ++R V + Y ++ F ++R YF++ +P +L + L+ + F++ D Sbjct: 179 KDYRGWKHWVYYTCCPDTPYLDITYHFIMQRIPLYFVVNVIIPCLLFSFLTVLVFYLPTD 238 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKI-PYVKAIDMYLMGCFVFVFLALLEYAFVNY 329 S ++ L I+ +L++T + E +P V I Y++ +FV +++ V Sbjct: 239 -SGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMIFVISSIIVTVVVIN 297 Query: 330 IFFGRGPQRQKKLAEKTAKAKNDRSKSESN 359 R P + A++ +S ES+ Sbjct: 298 T-HHRSPSTHSAIEGVKYIAEHMKSDEESS 326 >4AQ5-A nrPDB Length = 461 Score = 55.5 bits (132), Expect = 5e-08, Method: Compositional matrix adjust. Identities = 65/317 (20%), Positives = 136/317 (42%), Gaps = 25/317 (7%) Query: 17 VLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMV 75 VL+ CC + V LL+ Y+ +RP + V + + + + + V Sbjct: 12 VLLLFSCCGLVLGSEHETRLVA----NLLENYNKVIRPVEHHTHFVDITVGLQLIQLINV 67 Query: 76 SEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRV-ADQLWVPDTYFLNDKK---SFV 131 EVN + +Q W D RL ++ R+ +D +W+PD N+ + V Sbjct: 68 DEVNQIVETNVRLRQQWIDVRLRWNPADYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIV 127 Query: 132 HGVTVKNRMIRLHPD--GTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDI 189 H M +L D G +++ + C + + +P D+QNCT+++ + Y + Sbjct: 128 H-------MTKLLLDYTGKIMWTPPAIFKSYCEIIVTHFPFDQQNCTMKLGIWTYDGTKV 180 Query: 190 EFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATG---AYPRLSLSFRLKRNIGYF 246 ++ +E ++ + ++R V + Y ++ F ++R YF Sbjct: 181 SISPESDRPDLSTF--MESGEWVMKDYRGWKHWVYYTCCPDTPYLDITYHFIMQRIPLYF 238 Query: 247 ILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI-PYVKA 305 ++ +P +L + L+ + F++ D S ++ L I+ +L++T + E +P V Sbjct: 239 VVNVIIPCLLFSFLTVLVFYLPTD-SGEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPL 297 Query: 306 IDMYLMGCFVFVFLALL 322 I Y++ +FV +++ Sbjct: 298 IGKYMLFTMIFVISSII 314 >4UXU-A nrPDB Length = 218 Score = 50.8 bits (120), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 49/213 (23%), Positives = 90/213 (42%), Gaps = 14/213 (6%) Query: 36 FVKETVDKLLKGYDIRLRPDFGGPPVC-VGMNIDIASIDMVSEVNMDYTLTMYFQQYWRD 94 + ++ + L + Y LRP V V + I ++ I + E N T ++ +Q W D Sbjct: 5 YAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWHD 64 Query: 95 KRLAYSGIPLNLTLDNRV-ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGL 153 L + + R+ +D +W PD N K+ N + L DG + + Sbjct: 65 AYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN--KADDESSEPVNTNVVLRYDGLITWDA 122 Query: 154 RITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFY--WRGGDKAVTGVERIELPQF 211 T ++C++D+ +P D Q C L S+ Y + ++ + GD + +E +E Sbjct: 123 PAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLS-DFIEDVEWE-- 179 Query: 212 SIVEHRLVSRNVV---FATGAYPRLSLSFRLKR 241 V +NV+ + YP ++ + LKR Sbjct: 180 --VHGMPAVKNVISYGCCSEPYPDVTFTLLLKR 210 >3IGQ-A nrPDB Length = 201 Score = 42.7 bits (99), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 27/120 (22%), Positives = 50/120 (41%), Gaps = 4/120 (3%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 9 PPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 68 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RR D Q Sbjct: 69 EAIWIPEIRFVNVENARDADVV----DISVSPDGTVQYLERFSARVLSPLDGRRTESDSQ 124 >2QC1-B nrPDB Length = 212 Score = 37.4 bits (85), Expect = 0.015, Method: Compositional matrix adjust. Identities = 33/146 (22%), Positives = 64/146 (43%), Gaps = 8/146 (5%) Query: 43 KLLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG 101 KL + Y +RP + V V + + + + V EVN T + +Q W D L ++ Sbjct: 11 KLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYNLKWN- 69 Query: 102 IPLNLTLDNRV---ADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTT 158 P + ++ ++++W PD N+ VK + L G + + Sbjct: 70 -PDDYGGVKKIHIPSEKIWRPDVVLYNNADG--DFAIVKFTKVLLDYTGHITWTPPAIFK 126 Query: 159 AACMMDLRRYPLDEQNCTLEIESYGY 184 + C + + +P DEQNC++++ + Y Sbjct: 127 SYCEIIVTHFPFDEQNCSMKLGTRTY 152 >4MRS-A nrPDB Length = 614 Score = 31.2 bits (69), Expect = 0.96, Method: Compositional matrix adjust. Identities = 28/104 (26%), Positives = 43/104 (41%), Gaps = 25/104 (24%) Query: 232 RLSLSFRLKRNIG-----------------YFILQTYMPSILITILSWVSFWINYD---- 270 +LSL F L R G YF+L P+++ V FW+N+ Sbjct: 126 KLSLRFHLARRTGEVTKVIERGTKSIDTMLYFLLFNIAPTVIELTAVIVIFWLNFGLGLV 185 Query: 271 -ASAARVALGITTVLTMTTINTHLRETLPKI---PYVKAIDMYL 310 A+ V + T T+T THLRE + ++ +A+D L Sbjct: 186 TATILAVIAYVWTTRTITEWRTHLREKMNRLDGQALARAVDSLL 229 >4UM3-P nrPDB Length = 228 Score = 31.2 bits (69), Expect = 0.98, Method: Compositional matrix adjust. Identities = 31/121 (25%), Positives = 52/121 (42%), Gaps = 13/121 (10%) Query: 48 YDIRL--RPDF---GGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAY--S 100 Y+IR RPD PV V +++ +I V+E+ + + + Q W D+ LA+ S Sbjct: 27 YNIRQTSRPDVIPTQRRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSS 86 Query: 101 GIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAA 160 P +++ LWVPD N + + ++ + DG V Y I + Sbjct: 87 HSPDQVSVP---ISSLWVPDLAAYN---AISKPEVLTPQLAHVVSDGEVQYTPSIRQRFS 140 Query: 161 C 161 C Sbjct: 141 C 141 >2LCK-A nrPDB Length = 303 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 19/55 (34%), Positives = 26/55 (47%), Gaps = 2/55 (3%) Query: 158 TAACMMDLRRYPLDEQNCTLEI--ESYGYTTDDIEFYWRGGDKAVTGVERIELPQ 210 TAAC+ DL +PLD L+I ES G +RG + + R E P+ Sbjct: 10 TAACIADLITFPLDTAKVRLQIQGESQGLVRTAASAQYRGVLGTILTMVRTEGPR 64 >3FKD-A nrPDB Length = 350 Score = 30.0 bits (66), Expect = 2.4, Method: Compositional matrix adjust. Identities = 16/50 (32%), Positives = 29/50 (58%), Gaps = 4/50 (8%) Query: 127 KKSFVHGVTVKNRM--IRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQN 174 +++ V +T NR+ + +HP GT + LR+ A +L++Y L+E N Sbjct: 254 QRNTVDFITALNRLDGVEVHPSGTTFFLLRLKKGTAA--ELKKYMLEEYN 301 >5DTU-A nrPDB Length = 475 Score = 29.6 bits (65), Expect = 2.7, Method: Compositional matrix adjust. Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 1/55 (1%) Query: 63 VGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLW 117 G ID+ + +V NM T+ Y + R R SG+ + L N AD ++ Sbjct: 375 AGRGIDVPDVSLVVNFNMPSTIEAYTHRIGRTGRAGKSGVAITF-LGNEDADVMY 428 >5XYI-g nrPDB Length = 335 Score = 28.9 bits (63), Expect = 4.7, Method: Compositional matrix adjust. Identities = 19/78 (24%), Positives = 32/78 (41%) Query: 366 NILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKK 425 N + S+E+ NE N + D + + Q+ GH F+ D SL Sbjct: 33 NAAIESIEIDNEHNYLVSASRDKSALVWKLNRTQEQWATPFTRLIGHNHFVSDVSLSRDA 92 Query: 426 THLRRRSSQLKIKIPDLT 443 +HL S +++ DL+ Sbjct: 93 SHLLTSSWDSTLRLWDLS 110 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 6HUO-B nrPDB 618 e-177 6HUO-C nrPDB 445 e-125 6DW1-E nrPDB 437 e-123 6DW0-D nrPDB 437 e-123 4COF-A nrPDB 422 e-118 6HUJ-A nrPDB 410 e-115 5O8F-A nrPDB 407 e-114 6D6T-A nrPDB 401 e-112 6D6U-E nrPDB 362 e-100 6D6T-B nrPDB 351 4e-97 6A96-A nrPDB 346 9e-96 6DW1-C nrPDB 341 6e-94 5CFB-A nrPDB 316 1e-86 6D6T-E nrPDB 315 2e-86 3JAE-A nrPDB 315 3e-86 4AQ5-A nrPDB 307 1e-83 2BG9-A nrPDB 306 1e-83 2BG9-E nrPDB 303 1e-82 4BOG-3 nrPDB 302 2e-82 3RI5-A nrPDB 285 3e-77 2BG9-C nrPDB 282 2e-76 2BG9-B nrPDB 282 2e-76 4BOG-1 nrPDB 281 4e-76 6CNK-A nrPDB 281 5e-76 4BOT-B nrPDB 280 1e-75 4X5T-A nrPDB 277 9e-75 5KXI-B nrPDB 264 5e-71 5OSB-A nrPDB 256 2e-68 3TLU-A nrPDB 253 1e-67 6HIS-A nrPDB 250 1e-66 4YEU-A nrPDB 247 8e-66 6CDU-A nrPDB 246 2e-65 2YKS-A nrPDB 230 2e-60 5FJV-A nrPDB 200 2e-51 6FL9-A nrPDB 197 9e-51 4UXU-A nrPDB 182 3e-46 3IGQ-A nrPDB 144 5e-35 2M6B-A nrPDB 122 2e-28 1VRY-A nrPDB 76 3e-14 Sequences not found previously or not previously below threshold: 2QC1-B nrPDB 178 3e-45 5AFN-A nrPDB 111 9e-25 1OED-E nrPDB 99 4e-21 1OED-B nrPDB 98 7e-21 1OED-A nrPDB 94 9e-20 1OED-C nrPDB 94 1e-19 4AOE-A nrPDB 91 1e-18 4ZJS-A nrPDB 89 5e-18 2KSR-A nrPDB 85 7e-17 2LLY-A nrPDB 83 2e-16 4AOD-A nrPDB 83 3e-16 4AFG-A nrPDB 83 3e-16 2LM2-A nrPDB 79 3e-15 4UM3-P nrPDB 77 1e-14 2MAW-A nrPDB 73 3e-13 2BJ0-A nrPDB 71 1e-12 3SH1-A nrPDB 71 1e-12 2XZ5-A nrPDB 67 2e-11 2LKG-A nrPDB 57 2e-08 4MRS-A nrPDB 32 0.42 5SVA-Z nrPDB 31 1.3 5OQJ-7 nrPDB 31 1.3 3N71-A nrPDB 31 1.5 5CYO-A nrPDB 31 1.6 6D47-A nrPDB 30 3.0 2DCK-A nrPDB 28 7.9 >6HUO-B nrPDB Length = 473 Score = 618 bits (1594), Expect = e-177, Method: Composition-based stats. Identities = 447/448 (99%), Positives = 448/448 (100%) Query: 26 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85 +SVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT Sbjct: 26 RSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85 Query: 86 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP Sbjct: 86 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145 Query: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER Sbjct: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205 Query: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF Sbjct: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265 Query: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA Sbjct: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 Query: 326 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGI 385 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGI Sbjct: 326 FVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGI 385 Query: 386 GDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDV 445 GDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDV Sbjct: 386 GDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDV 445 Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 NAIDRWSRIVFPFTFSLFNLVYWLYYVN Sbjct: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 >6HUO-C nrPDB Length = 495 Score = 445 bits (1144), Expect = e-125, Method: Composition-based stats. Identities = 162/441 (36%), Positives = 242/441 (54%), Gaps = 38/441 (8%) Query: 37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 V ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+R Sbjct: 66 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 125 Query: 97 LAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 L ++ L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T Sbjct: 126 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 185 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 A C + L +P+DE +C LE SYGY ++I + W+ V L QFS V Sbjct: 186 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGL 245 Query: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276 R + V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR Sbjct: 246 RNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPART 305 Query: 277 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGP 336 +LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P Sbjct: 306 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKP 365 Query: 337 QRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVH-NEMNEVSG-GIGDTRNSA-- 392 + K +K + K+ + + + + H E +E G D ++ A Sbjct: 366 SKDKDKKKKNPLLRMFSFKAPTIDIRPRSATIQMNNATHLQERDEEYGYECLDGKDCASF 425 Query: 393 -ISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRW 451 F++ R G R H + H+R + +D + Sbjct: 426 FCCFEDC----------RTGAWR--------HGRIHIR---------------IAKMDSY 452 Query: 452 SRIVFPFTFSLFNLVYWLYYV 472 +RI FP F LFNLVYW+ Y+ Sbjct: 453 ARIFFPTAFCLFNLVYWVSYL 473 >6DW1-E nrPDB Length = 384 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 292/335 (87%), Positives = 311/335 (92%) Query: 1 MWGLAGGRLFGIFSAPVLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPP 60 MW + G+ S PV+VA+VCCA S N+P NMS+VKETVD+LLKGYDIRLRPDFGGPP Sbjct: 1 MWTVQNRESLGLLSFPVMVAMVCCAHSSNEPSNMSYVKETVDRLLKGYDIRLRPDFGGPP 60 Query: 61 VCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPD 120 V VGM ID+ASIDMVSEVNMDYTLTMYFQQ W+DKRL+YSGIPLNLTLDNRVADQLWVPD Sbjct: 61 VDVGMRIDVASIDMVSEVNMDYTLTMYFQQSWKDKRLSYSGIPLNLTLDNRVADQLWVPD 120 Query: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE Sbjct: 121 TYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIE 180 Query: 181 SYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLK 240 SYGYTTDDIEFYW GG+ AVTGV +IELPQFSIV++++VS+ V F TGAYPRLSLSFRLK Sbjct: 181 SYGYTTDDIEFYWNGGEGAVTGVNKIELPQFSIVDYKMVSKKVEFTTGAYPRLSLSFRLK 240 Query: 241 RNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI 300 RNIGYFILQTYMPS LITILSWVSFWINYDASAARVALGITTVLTMTTI+THLRETLPKI Sbjct: 241 RNIGYFILQTYMPSTLITILSWVSFWINYDASAARVALGITTVLTMTTISTHLRETLPKI 300 Query: 301 PYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335 PYVKAID+YLMGCFVFVFLALLEYAFVNYIFFG Sbjct: 301 PYVKAIDIYLMGCFVFVFLALLEYAFVNYIFFGGT 335 Score = 63.7 bits (153), Expect = 2e-10, Method: Composition-based stats. Identities = 28/35 (80%), Positives = 33/35 (94%) Query: 439 IPDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 IPDLTDVN+ID+WSR+ FP TFSLFN+VYWLYYV+ Sbjct: 336 IPDLTDVNSIDKWSRMFFPITFSLFNVVYWLYYVH 370 >6DW0-D nrPDB Length = 490 Score = 437 bits (1123), Expect = e-123, Method: Composition-based stats. Identities = 164/440 (37%), Positives = 244/440 (55%), Gaps = 44/440 (10%) Query: 37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 V ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+R Sbjct: 65 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 124 Query: 97 LAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 L ++ L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T Sbjct: 125 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 184 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 A C + L +P+DE +C LE SYGY ++I + W+ V L QFS V Sbjct: 185 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGL 244 Query: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276 R + V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR Sbjct: 245 RNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPART 304 Query: 277 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGP 336 +LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y R P Sbjct: 305 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHYFVSNRKP 364 Query: 337 QRQKKLAEKTAKAKND-RSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSA--- 392 + K +K D R +S + +++ T L+ +E E D ++ A Sbjct: 365 SKDKDKKKKNPAPTIDIRPRSATIQMNN-----ATHLQERDE--EYGYECLDGKDCASFF 417 Query: 393 ISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWS 452 F++ R G R H + H+R + +D ++ Sbjct: 418 CCFEDC----------RTGAWR--------HGRIHIR---------------IAKMDSYA 444 Query: 453 RIVFPFTFSLFNLVYWLYYV 472 RI FP F LFNLVYW+ Y+ Sbjct: 445 RIFFPTAFCLFNLVYWVSYL 464 >4COF-A nrPDB Length = 355 Score = 422 bits (1084), Expect = e-118, Method: Composition-based stats. Identities = 309/324 (95%), Positives = 311/324 (95%), Gaps = 1/324 (0%) Query: 25 AQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 84 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL Sbjct: 3 GQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 62 Query: 85 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 144 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH Sbjct: 63 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 122 Query: 145 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 204 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE Sbjct: 123 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 182 Query: 205 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 264 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS Sbjct: 183 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 242 Query: 265 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 324 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY Sbjct: 243 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 302 Query: 325 AFVNYIFFGRGPQRQKKLAEKTAK 348 AFVNYIFF P R + + Sbjct: 303 AFVNYIFF-SQPARAAAIDRWSRI 325 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 27/28 (96%), Positives = 27/28 (96%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 AIDRWSRIVFPFTFSLFNLVYWLYYVN Sbjct: 317 AAIDRWSRIVFPFTFSLFNLVYWLYYVN 344 >6HUJ-A nrPDB Length = 464 Score = 410 bits (1053), Expect = e-115, Method: Composition-based stats. Identities = 156/454 (34%), Positives = 235/454 (51%), Gaps = 60/454 (13%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 46 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 105 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 106 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 165 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 166 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 225 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 226 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 285 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 286 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 344 Query: 331 FFGRG---------PQRQKKLAEKTAKAKNDRSKSESNRVD--AHGNILLTSLEVHNEMN 379 F RG P++ KK+ + K N + + ++ A G+ L ++ Sbjct: 345 FTKRGYAWDGKSVVPEKPKKVKDPLIKKNNTYAPTATSYTPNLARGDPGLATI------- 397 Query: 380 EVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKI 439 A S + + ++ P E F Sbjct: 398 ------------AKSATIEPKEVKPETKPPEPKKTF------------------------ 421 Query: 440 PDLTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 V+ IDR SRI FP F +FNLVYW Y+N Sbjct: 422 ---NSVSKIDRLSRIAFPLLFGIFNLVYWATYLN 452 >5O8F-A nrPDB Length = 367 Score = 407 bits (1045), Expect = e-114, Method: Composition-based stats. Identities = 267/324 (82%), Positives = 288/324 (88%), Gaps = 1/324 (0%) Query: 25 AQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 84 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL Sbjct: 3 GQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTL 62 Query: 85 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 144 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH Sbjct: 63 TMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLH 122 Query: 145 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 204 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE Sbjct: 123 PDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE 182 Query: 205 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVS 264 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYF++QTY+P I+ ILS VS Sbjct: 183 RIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFVIQTYLPCIMTVILSQVS 242 Query: 265 FWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEY 324 FW+N ++ AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+ Sbjct: 243 FWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEF 302 Query: 325 AFVNYIFFGRGPQRQKKLAEKTAK 348 A VNY F P R K+ + + Sbjct: 303 ATVNY-FTKSQPARAAKIDKMSRI 325 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 17/28 (60%), Positives = 19/28 (67%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 ID+ SRIVFP F FNLVYW Y+N Sbjct: 317 AKIDKMSRIVFPILFGTFNLVYWATYLN 344 >6D6T-A nrPDB Length = 341 Score = 401 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 285/323 (88%), Positives = 301/323 (93%), Gaps = 1/323 (0%) Query: 26 QSVNDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLT 85 QSVNDP NMS VKETVD+LLKGYDIRLRPDFGGPPV VGMNIDIASIDMVSEVNMDYTLT Sbjct: 1 QSVNDPSNMSLVKETVDRLLKGYDIRLRPDFGGPPVAVGMNIDIASIDMVSEVNMDYTLT 60 Query: 86 MYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 145 MYFQQ WRDKRL+Y+ IPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP Sbjct: 61 MYFQQAWRDKRLSYNVIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHP 120 Query: 146 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVER 205 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRG D AVTGV + Sbjct: 121 DGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGDDNAVTGVTK 180 Query: 206 IELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSF 265 IELPQFSIV+++L+++ VVF+TG+YPRLSLSF+LKRNIGYFILQTYMPSILITILSWVSF Sbjct: 181 IELPQFSIVDYKLITKKVVFSTGSYPRLSLSFKLKRNIGYFILQTYMPSILITILSWVSF 240 Query: 266 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYA 325 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVF+ALLEYA Sbjct: 241 WINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFMALLEYA 300 Query: 326 FVNYIFFGRGPQRQKKLAEKTAK 348 VNYIFF P R + + Sbjct: 301 LVNYIFF-SQPARAAAIDRWSRI 322 Score = 54.4 bits (129), Expect = 1e-07, Method: Composition-based stats. Identities = 22/28 (78%), Positives = 23/28 (82%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 AIDRWSRI FP FS FN+VYWLYYVN Sbjct: 314 AAIDRWSRIFFPVVFSFFNIVYWLYYVN 341 >6D6U-E nrPDB Length = 394 Score = 362 bits (930), Expect = e-100, Method: Composition-based stats. Identities = 134/312 (42%), Positives = 194/312 (62%), Gaps = 1/312 (0%) Query: 37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 V ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+R Sbjct: 64 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 123 Query: 97 LAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 L ++ L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T Sbjct: 124 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 183 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 A C + L +P+DE +C LE SYGY ++I + W+ V L QFS V Sbjct: 184 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGL 243 Query: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276 R + V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR Sbjct: 244 RNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPART 303 Query: 277 ALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGP 336 +LGITTVLTMTT++T R++LPK+ YV A+D+++ CF+FVF AL+EY ++Y F P Sbjct: 304 SLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFSALVEYGTLHY-FVSSQP 362 Query: 337 QRQKKLAEKTAK 348 R K+ Sbjct: 363 ARAAKMDSYARI 374 Score = 49.8 bits (117), Expect = 2e-06, Method: Composition-based stats. Identities = 14/27 (51%), Positives = 19/27 (70%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYV 472 +D ++RI FP F LFNLVYW+ Y+ Sbjct: 366 AKMDSYARIFFPTAFCLFNLVYWVSYL 392 >6D6T-B nrPDB Length = 358 Score = 351 bits (900), Expect = 4e-97, Method: Composition-based stats. Identities = 127/319 (39%), Positives = 190/319 (59%), Gaps = 3/319 (0%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N + +D+LL GYD RLRP G V +I + S VS+ +M+YT+ ++F+Q W Sbjct: 11 NTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTSFGPVSDHDMEYTIDVFFRQSW 70 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T+ N+++R+ DGT+LY Sbjct: 71 KDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVAHNMTMPNKLLRITEDGTLLYT 130 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW--RGGDKAVTGVERIELPQ 210 +R+T A C M L +P+D C L+ SY YT ++ + W V + L Q Sbjct: 131 MRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVYEWTREPARSVVVAEDGSRLNQ 190 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + S V +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 191 YDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 250 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 251 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 309 Query: 331 FFGRGPQRQKKLAEKTAKA 349 F P R K+ + A Sbjct: 310 FTKSQPARAAKIDRLSRIA 328 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 17/28 (60%), Positives = 19/28 (67%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 IDR SRI FP F +FNLVYW Y+N Sbjct: 319 AKIDRLSRIAFPLLFGIFNLVYWATYLN 346 >6A96-A nrPDB Length = 392 Score = 346 bits (888), Expect = 9e-96, Method: Composition-based stats. Identities = 126/318 (39%), Positives = 190/318 (59%), Gaps = 3/318 (0%) Query: 33 NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYW 92 N++ +D LL GYD RLRP G V +I + S VS+ M+YT+ ++F+Q W Sbjct: 45 NITIFTRILDGLLDGYDNRLRPGLGERITQVRTDIYVTSFGPVSDTEMEYTIDVFFRQSW 104 Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 +D+RL + G L L+N +A ++W PDT+F N KKS H +T N+++RL DGT+LY Sbjct: 105 KDERLRFKGPMQRLPLNNLLASKIWTPDTFFHNGKKSIAHNMTTPNKLLRLEDDGTLLYT 164 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGD--KAVTGVERIELPQ 210 +R+T +A C M L +P+D C L+ SY Y ++ + W G V + L Q Sbjct: 165 MRLTISAECPMQLEDFPMDAHACPLKFGSYAYPNSEVVYVWTNGSTKSVVVAEDGSRLNQ 224 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 + ++ + + N+ +TG Y ++ F LKR IGYF++QTY+P I+ ILS VSFW+N + Sbjct: 225 YHLMGQTVGTENISTSTGEYTIMTAHFHLKRKIGYFVIQTYLPCIMTVILSQVSFWLNRE 284 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 + AR G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY Sbjct: 285 SVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY- 343 Query: 331 FFGRGPQRQKKLAEKTAK 348 F P R K+ + + Sbjct: 344 FTKSQPARAAKIDKMSRI 361 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 17/28 (60%), Positives = 19/28 (67%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 ID+ SRIVFP F FNLVYW Y+N Sbjct: 353 AKIDKMSRIVFPVLFGTFNLVYWATYLN 380 >6DW1-C nrPDB Length = 402 Score = 341 bits (873), Expect = 6e-94, Method: Composition-based stats. Identities = 127/343 (37%), Positives = 193/343 (56%), Gaps = 11/343 (3%) Query: 18 LVAVVCCAQSVNDPG------NMSFVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIAS 71 L+ +S P N + +D+LL GYD RLRP G V +I + S Sbjct: 16 LILSTLSGRSYGQPSQDELKDNTTVFTRILDRLLDGYDNRLRPGLGERVTEVKTDIFVTS 75 Query: 72 IDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFV 131 VS+ +M+YT+ ++F+Q W+D+RL + G L L+N +A ++W PDT+F N KKS Sbjct: 76 FGPVSDHDMEYTIDVFFRQSWKDERLKFKGPMTVLRLNNLMASKIWTPDTFFHNGKKSVA 135 Query: 132 HGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEF 191 H +T+ N+++R+ DGT+LY +R+T A C M L +P+D C L+ SY YT ++ + Sbjct: 136 HNMTMPNKLLRITEDGTLLYTMRLTVRAECPMHLEDFPMDAHACPLKFGSYAYTRAEVVY 195 Query: 192 YW--RGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQ 249 W V + L Q+ ++ + S V +TG Y ++ F LKR IGYF++Q Sbjct: 196 EWTREPARSVVVAEDGSRLNQYDLLGQTVDSGIVQSSTGEYVVMTTHFHLKRKIGYFVIQ 255 Query: 250 TYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMY 309 TY+P I+ ILS VSFW+N ++ AR G+TTVLTMTT++ R +LPK+ Y A+D + Sbjct: 256 TYLPCIMTVILSQVSFWLNRESVPARTVFGVTTVLTMTTLSISARNSLPKVAYATAMDWF 315 Query: 310 LMGCFVFVFLALLEYAFVNYIF---FGRGPQRQKKLAEKTAKA 349 + C+ FVF AL+E+A VNY + K+ + A Sbjct: 316 IAVCYAFVFSALIEFATVNYFTKRGTKKTFNSVSKIDRLSRIA 358 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 18/31 (58%), Positives = 21/31 (67%) Query: 443 TDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 V+ IDR SRI FP F +FNLVYW Y+N Sbjct: 346 NSVSKIDRLSRIAFPLLFGIFNLVYWATYLN 376 >5CFB-A nrPDB Length = 362 Score = 316 bits (809), Expect = 1e-86, Method: Composition-based stats. Identities = 143/315 (45%), Positives = 205/315 (65%), Gaps = 9/315 (2%) Query: 41 VDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 +DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D RL Sbjct: 14 LDKLMGRTSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQKWNDPRL 73 Query: 98 AYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 AYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY +R+T Sbjct: 74 AYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRIFKNGNVLYSIRLT 133 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 T +C MDL+ +P+D Q C +++ES+GYT +D+ F W+ + V E + LPQF + E Sbjct: 134 LTLSCPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWQ-DEAPVQVAEGLTLPQFLLKEE 192 Query: 217 R-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAAR 275 + L + TG + + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ AR Sbjct: 193 KDLRYCTKHYNTGKFTCIEVRFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPAR 252 Query: 276 VALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG 335 VALGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++ Sbjct: 253 VALGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRAGT 312 Query: 336 ---PQRQKKLAEKTA 347 R KK+ + Sbjct: 313 KVFIDRAKKIDTISR 327 Score = 36.7 bits (83), Expect = 0.020, Method: Composition-based stats. Identities = 12/25 (48%), Positives = 15/25 (60%) Query: 447 AIDRWSRIVFPFTFSLFNLVYWLYY 471 ID SR FP F +FN+ YW+ Y Sbjct: 321 KIDTISRACFPLAFLIFNIFYWVIY 345 >6D6T-E nrPDB Length = 366 Score = 315 bits (807), Expect = 2e-86, Method: Composition-based stats. Identities = 114/261 (43%), Positives = 164/261 (62%) Query: 37 VKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 V ++ LL+GYD +LRPD G P + ++ + SI V+ +NM+YT+ ++F Q W D+R Sbjct: 64 VTVILNNLLEGYDNKLRPDIGVKPTLIHTDMYVNSIGPVNAINMEYTIDIFFAQTWYDRR 123 Query: 97 LAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 L ++ L L++ + ++W+PDT+F N KK+ H +T NRM+R+ DG VLY LR+T Sbjct: 124 LKFNSTIKVLRLNSNMVGKIWIPDTFFRNSKKADAHWITTPNRMLRIWNDGRVLYTLRLT 183 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 A C + L +P+DE +C LE SYGY ++I + W+ V L QFS V Sbjct: 184 IDAECQLQLHNFPMDEHSCPLEFSSYGYPREEIVYQWKRSSVEVGDTRSWRLYQFSFVGL 243 Query: 217 RLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARV 276 R + V +G Y +S+ F L R +GYF +QTY+P LI +LSWVSFWIN DA AR Sbjct: 244 RNTTEVVKTTSGDYVVMSVYFDLSRRMGYFTIQTYIPCTLIVVLSWVSFWINKDAVPART 303 Query: 277 ALGITTVLTMTTINTHLRETL 297 +LGITTVLTMTT++T R++L Sbjct: 304 SLGITTVLTMTTLSTIARKSL 324 >3JAE-A nrPDB Length = 342 Score = 315 bits (806), Expect = 3e-86, Method: Composition-based stats. Identities = 145/320 (45%), Positives = 203/320 (63%), Gaps = 9/320 (2%) Query: 38 KETVDKLL---KGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRD 94 E +DKL+ GYD R+RP+F GPPV V NI I S ++E MDY + ++ +Q W D Sbjct: 3 SEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTMDYRVNIFLRQQWND 62 Query: 95 KRLAYSGIPLN-LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGL 153 RLAYS P + L LD + D +W PD +F N+K + H VT N+++R+ +G VLY + Sbjct: 63 PRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGANFHEVTTDNKLLRISKNGNVLYSI 122 Query: 154 RITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSI 213 RIT AC MDL+ +P+D Q C +++ES+GYT +D+ F W AV + + LPQF + Sbjct: 123 RITLVLACPMDLKNFPMDVQTCIMQLESFGYTMNDLIFEWDE-KGAVQVADGLTLPQFIL 181 Query: 214 VEHR-LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDAS 272 E + L + TG + + F L+R +GY+++Q Y+PS+LI ILSWVSFWIN DA+ Sbjct: 182 KEEKDLRYCTKHYNTGKFTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAA 241 Query: 273 AARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332 ARV LGITTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN+I Sbjct: 242 PARVGLGITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFIAR 301 Query: 333 GRG---PQRQKKLAEKTAKA 349 R K++ + A Sbjct: 302 AGTKLFISRAKRIDTVSRVA 321 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 12/30 (40%), Positives = 18/30 (60%) Query: 442 LTDVNAIDRWSRIVFPFTFSLFNLVYWLYY 471 ++ ID SR+ FP F +FN+ YW+ Y Sbjct: 308 ISRAKRIDTVSRVAFPLVFLIFNIFYWITY 337 >4AQ5-A nrPDB Length = 461 Score = 307 bits (785), Expect = 1e-83, Method: Composition-based stats. Identities = 64/330 (19%), Positives = 134/330 (40%), Gaps = 16/330 (4%) Query: 17 VLVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMV 75 VL+ CC + V LL+ Y+ +RP + V + + + + + V Sbjct: 12 VLLLFSCCGLVLGSEHETRLVA----NLLENYNKVIRPVEHHTHFVDITVGLQLIQLINV 67 Query: 76 SEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGV 134 EVN + +Q W D RL ++ R+ D +W+PD N+ V Sbjct: 68 DEVNQIVETNVRLRQQWIDVRLRWNPADYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIV 127 Query: 135 TVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWR 194 + L G +++ + C + + +P D+QNCT+++ + Y + Sbjct: 128 --HMTKLLLDYTGKIMWTPPAIFKSYCEIIVTHFPFDQQNCTMKLGIWTYDGTKVSISPE 185 Query: 195 GGDKAVTGVERIELPQFSIVEHRLVSRNVVFAT---GAYPRLSLSFRLKRNIGYFILQTY 251 ++ +E ++ + ++R V + Y ++ F ++R YF++ Sbjct: 186 SDRPDLST--FMESGEWVMKDYRGWKHWVYYTCCPDTPYLDITYHFIMQRIPLYFVVNVI 243 Query: 252 MPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI-PYVKAIDMYL 310 +P +L + L+ + F++ D+ ++ L I+ +L++T + E +P V I Y+ Sbjct: 244 IPCLLFSFLTVLVFYLPTDS-GEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYM 302 Query: 311 MGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 + +FV +++ V R P Sbjct: 303 LFTMIFVISSIIVTVVVINT-HHRSPSTHT 331 >2BG9-A nrPDB Length = 370 Score = 306 bits (783), Expect = 1e-83, Method: Composition-based stats. Identities = 64/328 (19%), Positives = 137/328 (41%), Gaps = 12/328 (3%) Query: 38 KETVDKLLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 V LL+ Y+ +RP + V + + + + + V EVN + +Q W D R Sbjct: 5 TRLVANLLENYNKVIRPVEHHTHFVDITVGLQLIQLINVDEVNQIVETNVRLRQQWIDVR 64 Query: 97 LAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155 L ++ R+ D +W+PD N+ V + L G +++ Sbjct: 65 LRWNPADYGGIKKIRLPSDDVWLPDLVLYNNADGDFAIV--HMTKLLLDYTGKIMWTPPA 122 Query: 156 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVE 215 + C + + +P D+QNCT+++ + Y + ++ +E ++ + + Sbjct: 123 IFKSYCEIIVTHFPFDQQNCTMKLGIWTYDGTKVSISPESDRPDLST--FMESGEWVMKD 180 Query: 216 HRLVSRNVVFAT---GAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDAS 272 +R V + Y ++ F ++R YF++ +P +L + L+ + F++ D+ Sbjct: 181 YRGWKHWVYYTCCPDTPYLDITYHFIMQRIPLYFVVNVIIPCLLFSFLTVLVFYLPTDS- 239 Query: 273 AARVALGITTVLTMTTINTHLRETLPKI-PYVKAIDMYLMGCFVFVFLALLEYAFVNYIF 331 ++ L I+ +L++T + E +P V I Y++ +FV +++ V Sbjct: 240 GEKMTLSISVLLSLTVFLLVIVELIPSTSSAVPLIGKYMLFTMIFVISSIIVTVVVINT- 298 Query: 332 FGRGPQRQKKLAEKTAKAKNDRSKSESN 359 R P + A++ +S ES+ Sbjct: 299 HHRSPSTHSAIEGVKYIAEHMKSDEESS 326 >2BG9-E nrPDB Length = 370 Score = 303 bits (776), Expect = 1e-82, Method: Composition-based stats. Identities = 65/335 (19%), Positives = 134/335 (40%), Gaps = 17/335 (5%) Query: 39 ETVDKLLKGYDIRLRPDFGGPPV-CVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 ++KLL YD R++P V V + + + ++ ++E T ++ + W D RL Sbjct: 5 RLIEKLLGDYDKRIKPAKTLDHVIDVTLKLTLTNLISLNEKEEALTTNVWIEIQWNDYRL 64 Query: 98 AYSGIPLNLTLDNRVADQL-WVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 +++ R+ +L W+PD N+ N ++ + DG++ + Sbjct: 65 SWNTSEYEGIDLVRIPSELLWLPDVVLENNVDGQFEVAYYANVLV--YNDGSMYWLPPAI 122 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 + C + + +P D QNC+L S Y ++ ++ + + E +++I H Sbjct: 123 YRSTCPIAVTYFPFDWQNCSLVFRSQTYNAHEVNLQL-SAEEGIDPEDFTENGEWTI-RH 180 Query: 217 RLVSRNVVFATG----AYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDAS 272 R +N + + + ++R ++I+ P +LI+ L + +++ A Sbjct: 181 RPAKKNYNWQLTKDDIDFQEIIFFLIIQRKPLFYIINIIAPCVLISSLVVLVYFLPAQAG 240 Query: 273 AARVALGITTVLTMTTINTHLRETLPKIPY-VKAIDMYLMGCFVFVFLALLEYAFVNYIF 331 + L I+ +L T + + +P+ V I YL+ FV L ++ + Sbjct: 241 GQKCTLSISVLLAQTIFLFLIAQKVPETSLNVPLIGKYLIFVM-FVSLVIVTNCVIVLNV 299 Query: 332 FGRGPQRQK-----KLAEKTAKAKNDRSKSESNRV 361 R P K+ K +ND N V Sbjct: 300 SLRTPNTHSCVEACNFIAKSTKEQNDSGSENENWV 334 >4BOG-3 nrPDB Length = 505 Score = 302 bits (773), Expect = 2e-82, Method: Composition-based stats. Identities = 67/365 (18%), Positives = 140/365 (38%), Gaps = 34/365 (9%) Query: 18 LVAVVCCAQSV--NDPGNMSFVKETVDKLLKGYDIRLRPDFGGPPV-CVGMNIDIASIDM 74 L+ ++C A V N+ G + ++KLL YD R++P V V + + + ++ Sbjct: 5 LLLIICLALEVRSNEEGRL------IEKLLGDYDKRIKPAKTLDHVIDVTLKLTLTNLIS 58 Query: 75 VSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVADQL-WVPDTYFLNDKKSFVHG 133 ++E T ++ + W D RL+++ R+ +L W+PD N+ Sbjct: 59 LNEKEEALTTNVWIEIQWNDYRLSWNTSEYEGIDLVRIPSELLWLPDVVLENNVDGQFEV 118 Query: 134 VTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYW 193 N ++ + DG++ + + C + + +P D QNC+L S Y ++ Sbjct: 119 AYYANVLV--YNDGSMYWLPPAIYRSTCPIAVTYFPFDWQNCSLVFRSQTYNAHEVNLQL 176 Query: 194 RGGDKAVTGV------ERIELPQFSIVEHRLVSRNVVFATG----AYPRLSLSFRLKRNI 243 + V + E +++I HR +N + + + ++R Sbjct: 177 SAEEGEVVEWIHIDPEDFTENGEWTI-RHRPAKKNYNWQLTKDDIDFQEIIFFLIIQRKP 235 Query: 244 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPY- 302 ++I+ P +LI+ L + +++ A + L I+ +L T + + +P+ Sbjct: 236 LFYIINIIAPCVLISSLVVLVYFLPAQAGGQKCTLSISVLLAQTIFLFLIAQKVPETSLN 295 Query: 303 VKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAE---------KTAKAKNDR 353 V I YL+ FV L ++ + R P + + Sbjct: 296 VPLIGKYLIFVM-FVSLVIVTNCVIVLNVSLRTPNTHSLSEKIKHLFLEFLPKYLGMHLE 354 Query: 354 SKSES 358 E+ Sbjct: 355 PSEET 359 >3RI5-A nrPDB Length = 347 Score = 285 bits (729), Expect = 3e-77, Method: Composition-based stats. Identities = 119/300 (39%), Positives = 178/300 (59%), Gaps = 9/300 (3%) Query: 38 KETVDKLL-KGYDIRLRPDF-GGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDK 95 + + L GYD R+RP G PV V +N+ + +I + VNM+Y+ + ++ W DK Sbjct: 3 SKILAHLFTSGYDFRVRPPTDNGGPVVVSVNMLLRTISKIDVVNMEYSAQLTLRESWIDK 62 Query: 96 RLAY----SGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLY 151 RL+Y G P + L V Q+W+PDT+F N+K+++ H + N +IR+H DGTVLY Sbjct: 63 RLSYGVKGDGQPDFVIL--TVGHQIWMPDTFFPNEKQAYKHTIDKPNVLIRIHNDGTVLY 120 Query: 152 GLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVE-RIELPQ 210 +RI+ +C M L+ YP+D Q C++++ SY YTT DIE+ W+ V LP Sbjct: 121 SVRISLVLSCPMYLQYYPMDVQQCSIDLASYAYTTKDIEYLWKEHSPLQLKVGLSSSLPS 180 Query: 211 FSIVEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYD 270 F + V TG Y L + +LKR +++LQ Y+PS ++ I+SWVSFW + Sbjct: 181 FQLTNTSTTYCTSVTNTGIYSCLRTTIQLKREFSFYLLQLYIPSCMLVIVSWVSFWFDRT 240 Query: 271 ASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYI 330 A ARV LG+TT+LTMT + + LP + Y+KAID+++ C F+F ALLE+A VN+I Sbjct: 241 AIPARVTLGVTTLLTMTAQSAGINSQLPPVSYIKAIDVWIGACMTFIFCALLEFALVNHI 300 Score = 32.5 bits (72), Expect = 0.38, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 443 TDVNA-IDRWSRIVFPFTFSLFNLVYWLYY 471 D++ +D SR +FP F +FN++YW + Sbjct: 309 NDISKRVDLISRALFPVLFFVFNILYWSRF 338 >2BG9-C nrPDB Length = 369 Score = 282 bits (722), Expect = 2e-76, Method: Composition-based stats. Identities = 57/332 (17%), Positives = 141/332 (42%), Gaps = 25/332 (7%) Query: 38 KETVDKLL--KGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRD 94 + ++ LL Y+ +RP V + +++ ++++ + E + T ++ W D Sbjct: 5 ERLINDLLIVNKYNKHVRPVKHNNEVVNIALSLTLSNLISLKETDETLTTNVWMDHAWYD 64 Query: 95 KRLAYSGIPL-NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGL 153 RL ++ ++++ + +W+PD N+ + N ++R P+G V + Sbjct: 65 HRLTWNASEYSDISILRLRPELIWIPDIVLQNNNDGQYNVAYFCNVLVR--PNGYVTWLP 122 Query: 154 RITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSI 213 ++C +++ +P D QNC+L+ + Y ++I D + E ++ I Sbjct: 123 PAIFRSSCPINVLYFPFDWQNCSLKFTALNYNANEI-----SMDLIIDPEAFTENGEWEI 177 Query: 214 VEHRLVSRNVV----FATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINY 269 + H+ +N+ Y ++ ++R ++++ P +LI+ L+ ++F++ Sbjct: 178 I-HKPAKKNIYGDKFPNGTNYQDVTFYLIIRRKPLFYVINFITPCVLISFLAALAFYLPA 236 Query: 270 DASAARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVN- 328 ++ +++ I +L + LP+ A+ + L+G ++ ++L+ VN Sbjct: 237 ES-GEKMSTAICVLLAQAVFLLLTSQRLPE----TALAVPLIGKYLMFIMSLVTGVVVNC 291 Query: 329 ---YIFFGRGPQRQKKLAEKTAKAKNDRSKSE 357 F R P + K + K+ Sbjct: 292 GIVLNFHFRTPSTHSGIDSTNYIVKQIKEKNA 323 >2BG9-B nrPDB Length = 370 Score = 282 bits (721), Expect = 2e-76, Method: Composition-based stats. Identities = 75/321 (23%), Positives = 144/321 (44%), Gaps = 9/321 (2%) Query: 40 TVDKLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLA 98 + L + Y+ ++RP G V V + + + S+ +++E N + T +++ W D RL Sbjct: 7 LLSVLFENYNPKVRPSQTVGDKVTVRVGLTLTSLLILNEKNEEMTTSVFLNLAWTDYRLQ 66 Query: 99 YSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITT 157 + D + D +W PD +N+ N +++ G V + Sbjct: 67 WDPAAYEGIKDLSIPSDDVWQPDIVLMNNNDGSFEITLHVNVLVQ--HTGAVSWHPSAIY 124 Query: 158 TAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHR 217 ++C + + +P D QNCT+ +SY Y T ++ D + E Q+SI EH+ Sbjct: 125 RSSCTIKVMYFPFDWQNCTMVFKSYTYDTSEVILQHAL-DAMINQDAFTENGQWSI-EHK 182 Query: 218 LVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVA 277 +N +Y ++ ++R ++I+ T +P ILI+IL+ + F++ DA +++ Sbjct: 183 PSRKNWRSDDPSYEDVTFYLIIQRKPLFYIVYTIVPCILISILAILVFYLPPDA-GEKMS 241 Query: 278 LGITTVLTMTTINTHLRETLPKIPY-VKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGP 336 L I+ +L +T L + +P+ V I YLM + V +++ + V R P Sbjct: 242 LSISALLALTVFLLLLADKVPETSLSVPIIISYLMFIMILVAFSVIL-SVVVLNLHHRSP 300 Query: 337 QRQKKLAEKTAKAKNDRSKSE 357 + + A+ S SE Sbjct: 301 NTHEAVEAIKYIAEQLESASE 321 >4BOG-1 nrPDB Length = 522 Score = 281 bits (719), Expect = 4e-76, Method: Composition-based stats. Identities = 61/357 (17%), Positives = 145/357 (40%), Gaps = 38/357 (10%) Query: 17 VLVAVVCCAQS----VNDPGNMSFVKETVDKLL--KGYDIRLRP-DFGGPPVCVGMNIDI 69 V + + C S VN+ + ++ LL Y+ +RP V + +++ + Sbjct: 7 VYLLISCLYYSGCSGVNEE------ERLINDLLIVNKYNKHVRPVKHNNEVVNIALSLTL 60 Query: 70 ASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPL-NLTLDNRVADQLWVPDTYFLNDKK 128 +++ + E + T ++ W D RL ++ ++++ + +W+PD N+ Sbjct: 61 SNLISLKETDETLTTNVWMDHAWYDHRLTWNASEYSDISILRLRPELIWIPDIVLQNNND 120 Query: 129 SFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDD 188 + N ++R P+G V + ++C +++ +P D QNC+L+ + Y ++ Sbjct: 121 GQYNVAYFCNVLVR--PNGYVTWLPPAIFRSSCPINVLYFPFDWQNCSLKFTALNYNANE 178 Query: 189 I--EFYWRGGDKAVTGVERIELPQFSIVE-------HRLVSRNVV----FATGAYPRLSL 235 I + D +E I + + E H+ +N+ Y ++ Sbjct: 179 ISMDLMTDTIDGKDYPIEWIIIDPEAFTENGEWEIIHKPAKKNIYGDKFPNGTNYQDVTF 238 Query: 236 SFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRE 295 ++R ++++ P +LI+ L+ ++F++ ++ +++ I +L + Sbjct: 239 YLIIRRKPLFYVINFITPCVLISFLAALAFYLPAES-GEKMSTAICVLLAQAVFLLLTSQ 297 Query: 296 TLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVN----YIFFGRGPQRQKKLAEKTAK 348 LP+ A+ + L+G ++ ++L+ VN F R P Sbjct: 298 RLPE----TALAVPLIGKYLMFIMSLVTGVVVNCGIVLNFHFRTPSTHVLSTRVKQI 350 >6CNK-A nrPDB Length = 386 Score = 281 bits (718), Expect = 5e-76, Method: Composition-based stats. Identities = 69/315 (21%), Positives = 130/315 (41%), Gaps = 11/315 (3%) Query: 31 PGNMSFVKETVDKLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQ 89 + + KL GY+ RP V V + IA + V E N T ++ + Sbjct: 5 ETRAHAEERLLKKLFSGYNKWSRPVANISDVVLVRFGLSIAQLIDVDEKNQMMTTNVWVK 64 Query: 90 QYWRDKRLAYSGIPLNLTLDNRVADQ-LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGT 148 Q W D +L + R+ + +W PD N+ L DG Sbjct: 65 QEWHDYKLRWDPADYENVTSIRIPSELIWRPDIVLYNNADGDF--AVTHLTKAHLFHDGR 122 Query: 149 VLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIEL 208 V + ++C +D+ +P D+QNCT++ S+ Y I+ V ++ E Sbjct: 123 VQWTPPAIYKSSCSIDVTFFPFDQQNCTMKFGSWTYDKAKIDLV--NMHSRVDQLDFWES 180 Query: 209 PQFSIVE--HRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFW 266 ++ IV+ +R YP ++ +F ++R ++ + +P +LI+ L+ + F+ Sbjct: 181 GEWVIVDAVGTYNTRKYECCAEIYPDITYAFVIRRLPLFYTINLIIPCLLISCLTVLVFY 240 Query: 267 INYDASAARVALGITTVLTMTTINTHLRETLPKIPYV-KAIDMYLMGCFVFVFLALLEYA 325 + + ++ L I+ +L++T + E +P V I YL+ +FV L+++ Sbjct: 241 LPSEC-GEKITLCISVLLSLTVFLLLITEIIPSTSLVIPLIGEYLLFTMIFVTLSIVITV 299 Query: 326 FVNYIFFGRGPQRQK 340 FV R P+ Sbjct: 300 FV-LNVHHRSPRTHT 313 >4BOT-B nrPDB Length = 493 Score = 280 bits (715), Expect = 1e-75, Method: Composition-based stats. Identities = 84/446 (18%), Positives = 170/446 (38%), Gaps = 14/446 (3%) Query: 18 LVAVVCCAQSVNDPGNMSFVKETVDKLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVS 76 L VV A +++ G + L + Y+ ++RP G V V + + + S+ +++ Sbjct: 9 LGLVVMMALALSGVGASVMEDTLLSVLFENYNPKVRPSQTVGDKVTVRVGLTLTSLLILN 68 Query: 77 EVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVT 135 E N + T +++ W D RL + D + D +W PD +N+ Sbjct: 69 EKNEEMTTSVFLNLAWTDYRLQWDPAAYEGIKDLSIPSDDVWQPDIVLMNNNDGSFEITL 128 Query: 136 VKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRG 195 N +++ G V + ++C + + +P D QNCT+ +SY Y T ++ Sbjct: 129 HVNVLVQ--HTGAVSWHPSAIYRSSCTIKVMYFPFDWQNCTMVFKSYTYDTSEVILQHAL 186 Query: 196 GDKAVTGVERIELPQFSI-------VEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFIL 248 K V+ I + Q + +EH+ +N +Y ++ ++R ++I+ Sbjct: 187 DAKGEREVKEIMINQDAFTENGQWSIEHKPSRKNWRSDDPSYEDVTFYLIIQRKPLFYIV 246 Query: 249 QTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPY-VKAID 307 T +P ILI+IL+ + F++ DA +++L I+ +L +T L + +P+ V I Sbjct: 247 YTIVPCILISILAILVFYLPPDA-GEKMSLSISALLALTVFLLLLADKVPETSLSVPIII 305 Query: 308 MYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNI 367 YLM + V +++ + V R P + Sbjct: 306 SYLMFIMILVAFSVIL-SVVVLNLHHRSPNTHTMPNWIRQIFIETLPPFLWIQRPVTTPS 364 Query: 368 LLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTH 427 + + + N+ + DN+ + + + + E G Sbjct: 365 PDSKPTIISRANDEYFIRKPAGDFVCPVDNARVAVQPERLFSEMKWHLNGLTQPVTLPQD 424 Query: 428 LRRRSSQLKIKIPDLTDVNAIDRWSR 453 L+ +K L + D + Sbjct: 425 LKEAVEAIKYIAEQLESASEFDDLKK 450 >4X5T-A nrPDB Length = 330 Score = 277 bits (707), Expect = 9e-75, Method: Composition-based stats. Identities = 105/308 (34%), Positives = 160/308 (51%), Gaps = 30/308 (9%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 8 PPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 67 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RR+P+D Q Sbjct: 68 EAIWIPEIRFVNVENARDADV----VDISVSPDGTVQYLERFSARVLSPLDFRRFPMDSQ 123 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 124 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 181 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 + L R+ R +GY+++Q Y+PS+LI ILSW+SFWIN DA+ ARV LGI Sbjct: 182 K-----------LDYQLRISRQMGYYLIQMYIPSLLIVILSWISFWINMDAAPARVGLGI 230 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT ++ R +LPK+ YVKAID+++ C +FVF ALLEYA VN++ PQR K Sbjct: 231 TTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNFVSRQSQPQRAK 290 Query: 341 KLAEKTAK 348 K+ + + Sbjct: 291 KIDKISRI 298 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 13/25 (52%), Positives = 17/25 (68%) Query: 447 AIDRWSRIVFPFTFSLFNLVYWLYY 471 ID+ SRI FP F +FN+ YW+ Y Sbjct: 291 KIDKISRIGFPMAFLIFNMFYWIIY 315 >5KXI-B nrPDB Length = 403 Score = 264 bits (675), Expect = 5e-71, Method: Composition-based stats. Identities = 65/308 (21%), Positives = 130/308 (42%), Gaps = 12/308 (3%) Query: 38 KETVDKLLK--GYDIRLRPDFGG-PPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRD 94 + V+ LL Y+ +RP G V V + + +A + V E T ++ Q W D Sbjct: 5 ERLVEHLLDPSRYNKLIRPATNGSELVTVQLMVSLAQLISVHEREQIMTTNVWLTQEWED 64 Query: 95 KRLAYSGIPLNLTLDNRVADQ-LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGL 153 RL + + R+ + +W+PD N+ N ++ DG++ + Sbjct: 65 YRLTWKPEEFDNMKKVRLPSKHIWLPDVVLYNNADGMYEVSFYSNAVVSY--DGSIFWLP 122 Query: 154 RITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSI 213 +AC ++++ +P D+QNCT++ S+ Y +I+ + ++ + ++ I Sbjct: 123 PAIYKSACKIEVKHFPFDQQNCTMKFRSWTYDRTEIDLVLKSEVASLD--DFTPSGEWDI 180 Query: 214 VEHRLVSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASA 273 V RN Y ++ F ++R ++ + +P +LIT L+ + F++ D Sbjct: 181 VAL-PGRRNENPDDSTYVDITYDFIIRRKPLFYTINLIIPCVLITSLAILVFYLPSDC-G 238 Query: 274 ARVALGITTVLTMTTINTHLRETLPKIPY-VKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332 ++ L I+ +L +T + + +P V + YLM V V +++ V Sbjct: 239 EKMTLCISVLLALTVFLLLISKIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCV-LNVH 297 Query: 333 GRGPQRQK 340 R P Sbjct: 298 HRSPTTHT 305 >5OSB-A nrPDB Length = 336 Score = 256 bits (653), Expect = 2e-68, Method: Composition-based stats. Identities = 95/309 (30%), Positives = 147/309 (47%), Gaps = 31/309 (10%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 8 PPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 67 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RRYP D Q Sbjct: 68 EAIWIPEIRFVNVENARDADV----VDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ 123 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 124 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 181 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 + L R+ R GYF++QTY+P I+ ILS VSFW+N ++ AR + Sbjct: 182 K-----------LDYQLRISRQYGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVFVV 230 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY F P R Sbjct: 231 TTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY-FTKSQPARAA 289 Query: 341 KLAEKTAKA 349 K+ + A Sbjct: 290 KIDRLSRIA 298 Score = 52.5 bits (124), Expect = 3e-07, Method: Composition-based stats. Identities = 17/28 (60%), Positives = 19/28 (67%) Query: 446 NAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 IDR SRI FP F +FNLVYW Y+N Sbjct: 289 AKIDRLSRIAFPLLFGIFNLVYWATYLN 316 >3TLU-A nrPDB Length = 321 Score = 253 bits (646), Expect = 1e-67, Method: Composition-based stats. Identities = 70/309 (22%), Positives = 124/309 (40%), Gaps = 32/309 (10%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 13 PPIADEPLTVNTGIYLIESYSLDDCAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 72 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RRYP D Q Sbjct: 73 EAIWIPEIRFVNVENARDADV----VDISVSPDGTVQYLERFSARVLSPLDFRRYPFDSQ 128 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 129 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 186 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 + L R+ R +I +P + I +SW +FW + A V L + Sbjct: 187 K-----------LDYQLRISRQYFSYIPNIILPMLFILFISWTAFW--STSYEANVTLVV 233 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 +T++ N + LP PY+ + ++F F+A++E +Y+ P R Sbjct: 234 STLIAHIAFNILVETNLPCTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARAA 293 Query: 341 KLAEKTAKA 349 + + A Sbjct: 294 SITRASRIA 302 >6HIS-A nrPDB Length = 445 Score = 250 bits (637), Expect = 1e-66, Method: Composition-based stats. Identities = 87/439 (19%), Positives = 164/439 (37%), Gaps = 20/439 (4%) Query: 39 ETVDKLLKGYDIRLRPDFG-GPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 D LL Y +RP P V +++ + +I V E N T ++++QYW D+ L Sbjct: 7 RLSDHLLANYKKGVRPVRDWRKPTTVSIDVIMYAILNVDEKNQVLTTYIWYRQYWTDEFL 66 Query: 98 AYSGIPL-NLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 ++ N+T + D +WVPD + G + + +H G V + Sbjct: 67 QWTPEDFDNVTKLSIPTDSIWVPDILI---NEFVDVGKSPNIPYVYVHHRGEVQNYKPLQ 123 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQ--FSIV 214 AC +D+ +P D QNC+L S+ +T DI + V + I + Q + ++ Sbjct: 124 LVTACSLDIYNFPFDVQNCSLTFTSWLHTIQDINITLWRSPEEVRSDKSIFINQGEWELL 183 Query: 215 EHRLV-SRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASA 273 E + + +Y + ++R ++ + +PSI + ++ V F + D+ Sbjct: 184 EVFPQFKEFSIDISNSYAEMKFYVIIRRRPLFYAVSLLLPSIFLMVVDIVGFCLPPDS-G 242 Query: 274 ARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFG 333 RV+ IT +L + + +TLP AI L+G + V +ALL + IF Sbjct: 243 ERVSFKITLLLGYSVFLIIVSDTLP----ATAIGTPLIGVYFVVCMALLVISLAETIFIV 298 Query: 334 RGPQRQKKLAEKTAKAKNDRSKSESNRVDAHGNILLTSLEVHNEMNEVSGGIGDTRNSAI 393 R +Q L + G + + T + + Sbjct: 299 RLVHKQ-DLQRPVPDWLRHLVLDRIAWILCLGEQPMAH------RPPATFQANKTDDCSA 351 Query: 394 SFDNSGIQYRKQSMPREGHGRFLGDRSLPHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSR 453 ++ Q + + GR +R +L L + + +R Sbjct: 352 MGNHCSHVGGPQDLEKTPRGRGSPLPPPREASLAVRGLLQELSSIRHFLEKRDEMREVAR 411 Query: 454 IVFPFTFSLFNLVYWLYYV 472 + L L++ +Y + Sbjct: 412 DWLRVGYVLDRLLFRIYLL 430 >4YEU-A nrPDB Length = 312 Score = 247 bits (630), Expect = 8e-66, Method: Composition-based stats. Identities = 75/310 (24%), Positives = 122/310 (39%), Gaps = 35/310 (11%) Query: 60 PVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG----IPLNLTLDNRVADQ 115 PV V ++I I I V+ + Y + Y W K G I N ++ + + Sbjct: 1 PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINNG 60 Query: 116 LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQNC 175 LWVP F+N V N+ + L PDG V+Y R + + MD R +P D Q Sbjct: 61 LWVPALEFIN----VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQF 116 Query: 176 TLEIESYGYTTDDIEF----------------YWRGGDKAVTGVERIELPQFSIVEHRLV 219 LE+E + Y + F W KA T + I S V+ Sbjct: 117 VLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPN-- 174 Query: 220 SRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALG 279 + R+++ RN +I +P + I +SW +FW + A V L Sbjct: 175 -------QNEFSRITVRIDAVRNYFSYIPNIILPMLFILFISWTAFW--STSYEANVTLV 225 Query: 280 ITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQ 339 ++T++ N + LPK PY+ + ++F F+A++E +Y+ P R Sbjct: 226 VSTLIAHIAFNILVETNLPKTPYMTYTGAIIFMIYLFYFVAVIEVTVQHYLKVESQPARA 285 Query: 340 KKLAEKTAKA 349 + + A Sbjct: 286 ASITRASRIA 295 >6CDU-A nrPDB Length = 324 Score = 246 bits (627), Expect = 2e-65, Method: Composition-based stats. Identities = 100/311 (32%), Positives = 146/311 (46%), Gaps = 34/311 (10%) Query: 59 PPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG----IPLNLTLDNRVAD 114 PV V ++I I I V+ + Y + Y W K G I N ++ + + Sbjct: 10 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINN 69 Query: 115 QLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQN 174 LWVP F+N V N+ + L PDG V+Y R + + MD R +P D Q Sbjct: 70 GLWVPALEFIN----VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQ 125 Query: 175 CTLEIESYGYTTDDIEF----------------YWRGGDKAVTGVERIELPQFSIVEHRL 218 LE+E + Y + F W KA T + I S V+ Sbjct: 126 FVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRGKASTHISDIRYDHLSSVQPN- 184 Query: 219 VSRNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVAL 278 + R+++ R IGYF++QTY+P I+ ILS VSFW+N ++ AR Sbjct: 185 --------QNEFSRITVRIDAVRKIGYFVIQTYLPCIMTVILSQVSFWLNRESVPARTVF 236 Query: 279 GITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQR 338 G+TTVLTMTT++ R +LPK+ Y A+D ++ C+ FVF AL+E+A VNY F RG + Sbjct: 237 GVTTVLTMTTLSISARNSLPKVAYATAMDWFIAVCYAFVFSALIEFATVNY-FTKRGVES 295 Query: 339 QKKLAEKTAKA 349 K+ + A Sbjct: 296 VSKIDRLSRIA 306 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 18/32 (56%), Positives = 22/32 (68%) Query: 442 LTDVNAIDRWSRIVFPFTFSLFNLVYWLYYVN 473 + V+ IDR SRI FP F +FNLVYW Y+N Sbjct: 293 VESVSKIDRLSRIAFPLLFGIFNLVYWATYLN 324 >2YKS-A nrPDB Length = 321 Score = 230 bits (585), Expect = 2e-60, Method: Composition-based stats. Identities = 72/281 (25%), Positives = 117/281 (41%), Gaps = 16/281 (5%) Query: 59 PPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSG----IPLNLTLDNRVAD 114 PV V ++I I I V+ + Y + Y W K G I N ++ + + Sbjct: 10 RPVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVENTQIERWINN 69 Query: 115 QLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQN 174 LWVP F+N V N+ + L PDG V+Y R + + MD R +P D Q Sbjct: 70 GLWVPALEFIN----VVGSPDTGNKRLMLFPDGRVIYNARFLGSFSNDMDFRLFPFDRQQ 125 Query: 175 CTLEIESYGYTTD-----DIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS-RNVVFATG 228 LE+E + Y DI+ Y D I I + R +V Sbjct: 126 FVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEWWIRKASTHISDIRYDHLSSVQPNQN 185 Query: 229 AYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTT 288 + R+++ RN Y++ +P LI SW FW+ ++ + R+ T +LT+ Sbjct: 186 EFSRITVRIDAVRNPSYYLWSFILPLGLIIAASWSVFWL--ESFSERLQTSFTLMLTVVA 243 Query: 289 INTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNY 329 + LP++PY ID ++ + +F A+L F ++ Sbjct: 244 YAAYTSNILPRLPYTTVIDQMIIAGYGSIFAAILLIIFAHH 284 >5FJV-A nrPDB Length = 213 Score = 200 bits (507), Expect = 2e-51, Method: Composition-based stats. Identities = 46/209 (22%), Positives = 83/209 (39%), Gaps = 8/209 (3%) Query: 39 ETVDKLLKGYDIRLRP-DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 L +GY+ RP V V + IA + V E N T ++ +Q W D +L Sbjct: 3 RLFKHLFRGYNRWARPVPNTSDVVIVRFGLSIAQLIDVDEKNQMMTTNVWLKQEWSDYKL 62 Query: 98 AYSGIPLNLTLDNRVADQ-LWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRIT 156 ++ RV + +W+PD N+ L GTV + Sbjct: 63 RWNPTDFGNITSLRVPSEMIWIPDIVLYNNADGEF--AVTHMTKAHLFSTGTVHWVPPAI 120 Query: 157 TTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEH 216 ++C +D+ +P D+QNC ++ S+ Y I+ ++ V + E +++IV Sbjct: 121 YKSSCSIDVTFFPFDQQNCKMKFGSWTYDKAKIDL--EQMEQTVDLKDYWESGEWAIVNA 178 Query: 217 RLV--SRNVVFATGAYPRLSLSFRLKRNI 243 S+ YP ++ +F ++R Sbjct: 179 TGTYNSKKYDCCAEIYPDVTYAFVIRRLP 207 >6FL9-A nrPDB Length = 320 Score = 197 bits (500), Expect = 9e-51, Method: Composition-based stats. Identities = 68/302 (22%), Positives = 129/302 (42%), Gaps = 26/302 (8%) Query: 55 DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIP---------LN 105 P V + + I I +++ ++++ + WR LA+ P L Sbjct: 3 SLAAEPSDVFIGLKIDQITGINQKEENFSVVGSLRIDWRQPLLAFEHAPGEPKHRTYTLA 62 Query: 106 LTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTA-ACMMD 164 L Q+ P + N + + +NR+I L DGTV+Y R T+T A D Sbjct: 63 TFLKLLEEKQIRWPAFTYHNQQGR----MDFQNRLISLSEDGTVMYLERFTSTFQAPAFD 118 Query: 165 LRRYPLDEQNCTLEIES----YGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVS 220 R +P D Q + ++S + + +++ + GD+ G E + + V L + Sbjct: 119 FRLFPFDNQLFFIHVDSIFPQHLFRFQEMQGFSGLGDQ--LGEEEWIVTE---VNTHLTT 173 Query: 221 RNVVFATGAYPRLSLSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGI 280 N F G R L F +R++ Y++++ +P +LI +SW +F++ R+ L Sbjct: 174 HNE-FTKGDASRFVLEFHAERHLNYYLMRILIPVLLIITVSWFTFFL--QDYTKRIDLAG 230 Query: 281 TTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 +L N + LP++ Y+ +D +L+G F+ L +L ++ + + Sbjct: 231 GNLLLFIAFNFTISSDLPRLGYITLMDAFLVGTFIITALVVLGNVWLRRLENHGKQALAR 290 Query: 341 KL 342 KL Sbjct: 291 KL 292 >4UXU-A nrPDB Length = 218 Score = 182 bits (462), Expect = 3e-46, Method: Composition-based stats. Identities = 47/213 (22%), Positives = 89/213 (41%), Gaps = 10/213 (4%) Query: 35 SFVKETVDKLLKGYDIRLRPDFGGPPV-CVGMNIDIASIDMVSEVNMDYTLTMYFQQYWR 93 + ++ + L + Y LRP V V + I ++ I + E N T ++ +Q W Sbjct: 4 KYAQKLFNDLFEDYSNALRPVEDTDKVLNVTLQITLSQIKDMDERNQILTAYLWIRQIWH 63 Query: 94 DKRLAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYG 152 D L + + R+ D +W PD N K+ N + L DG + + Sbjct: 64 DAYLTWDRDQYDGLDSIRIPSDLVWRPDIVLYN--KADDESSEPVNTNVVLRYDGLITWD 121 Query: 153 LRITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFS 212 T ++C++D+ +P D Q C L S+ Y + ++ + ++ + IE ++ Sbjct: 122 APAITKSSCVVDVTYFPFDNQQCNLTFGSWTYNGNQVDIFNALDSGDLS--DFIEDVEWE 179 Query: 213 IVEHRLVSRNVV---FATGAYPRLSLSFRLKRN 242 V +NV+ + YP ++ + LKR Sbjct: 180 -VHGMPAVKNVISYGCCSEPYPDVTFTLLLKRR 211 >2QC1-B nrPDB Length = 212 Score = 178 bits (452), Expect = 3e-45, Method: Composition-based stats. Identities = 40/211 (18%), Positives = 77/211 (36%), Gaps = 9/211 (4%) Query: 38 KETVDKLLKGYDIRLRPDF-GGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 KL + Y +RP V V + + + + V EVN T + +Q W D Sbjct: 6 TRLEAKLFEDYSSVVRPVEDHREIVQVTVGLQLIQLINVDEVNQIVTTNVRLKQQWVDYN 65 Query: 97 LAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155 L ++ + +++W PD N+ V + L G + + Sbjct: 66 LKWNPDDYGGVKKIHIPSEKIWRPDVVLYNNADGDFAIVKFTKVL--LDYTGHITWTPPA 123 Query: 156 TTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVE 215 + C + + +P DEQNC++++ + Y + ++ +E ++ I E Sbjct: 124 IFKSYCEIIVTHFPFDEQNCSMKLGTRTYDGSAVAINPESDQPDLS--NFMESGEWVIKE 181 Query: 216 HRLVSRNVV---FATGAYPRLSLSFRLKRNI 243 R V T Y ++ F ++R Sbjct: 182 ARGWKHWVFYSCCPTTPYLDITYHFVMQRLP 212 >3IGQ-A nrPDB Length = 201 Score = 144 bits (364), Expect = 5e-35, Method: Composition-based stats. Identities = 44/202 (21%), Positives = 76/202 (37%), Gaps = 30/202 (14%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V I + + + + + + W+D+RLA+ + + + Sbjct: 9 PPIADEPLTVNTGIYLIECYSLDDKAETFKVNAFLSLSWKDRRLAFDPVRSGVRVKTYEP 68 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQ 173 + +W+P+ F+N + + V I + PDGTV Y R + +D RR D Q Sbjct: 69 EAIWIPEIRFVNVENARDADV----VDISVSPDGTVQYLERFSARVLSPLDGRRTESDSQ 124 Query: 174 NCTLEIESYGYTTD--------DIEFYWRGGDKAVTGVE-----RIELPQFSIVEHRLVS 220 TL I + D D+E + D +TG + + P +E RL S Sbjct: 125 --TLHIYLIVRSVDTRNIVLAVDLEKVGKNDDVFLTGWDIESFTAVVKPANFALEDRLES 182 Query: 221 RNVVFATGAYPRLSLSFRLKRN 242 + L R+ R Sbjct: 183 K-----------LDYQLRISRQ 193 >2M6B-A nrPDB Length = 150 Score = 122 bits (307), Expect = 2e-28, Method: Composition-based stats. Identities = 62/116 (53%), Positives = 84/116 (72%), Gaps = 6/116 (5%) Query: 239 LKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLP 298 L+R +GY+++Q Y+PS+LI ILSW+SFWIN DA+ ARV LGITTVLT+TT ++ R +LP Sbjct: 2 LERQLGYYLIQLYIPSLLIVILSWISFWINLDAAPARVGLGITTVLTLTTQSSGSRASLP 61 Query: 299 KIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRG------PQRQKKLAEKTAK 348 K+ YVKAID++L C +FVF ALLEYA VN++ R QR KK+ + + Sbjct: 62 KVSYVKAIDIWLAVCLLFVFSALLEYAAVNFVSRQREFGGGGFIQRAKKIDKISRI 117 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 14/25 (56%), Positives = 17/25 (68%) Query: 447 AIDRWSRIVFPFTFSLFNLVYWLYY 471 ID+ SRI FP F +FNL YW+ Y Sbjct: 110 KIDKISRIGFPLAFLIFNLFYWIIY 134 >5AFN-A nrPDB Length = 207 Score = 111 bits (276), Expect = 9e-25, Method: Composition-based stats. Identities = 37/208 (17%), Positives = 75/208 (36%), Gaps = 7/208 (3%) Query: 36 FVKETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDK 95 F ++ +L+K Y+ + P PV V ++ + I V E N + + Q W D Sbjct: 3 FQRKLYKELVKNYNPDVIPTQRDRPVTVYFSLSLLQIMDVDEKNQVVDVVFWLQMSWTDH 62 Query: 96 RLAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLR 154 L ++ V LWVPD N + + ++ ++ G V Y Sbjct: 63 YLQWNVSEYPGVKQVSVPISSLWVPDLAAYN---AISKPEVLTPQLALVNSSGHVQYLPS 119 Query: 155 ITTTAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIV 214 I +C + C L+ S+ + + +++ + D ++G + V Sbjct: 120 IRQRFSCDVSGVDTESGA-TCKLKFGSWTHHSRELDLQMQEAD--ISGYIPYSRFELVGV 176 Query: 215 EHRLVSRNVVFATGAYPRLSLSFRLKRN 242 + R YP ++ + ++ Sbjct: 177 TQKRSERFYECCKEPYPDVTFTVTFRKK 204 >1OED-E nrPDB Length = 260 Score = 98.7 bits (244), Expect = 4e-21, Method: Composition-based stats. Identities = 20/126 (15%), Positives = 43/126 (34%), Gaps = 11/126 (8%) Query: 243 IGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPY 302 ++I+ P +LI+ L + +++ A + L I+ +L T + + +P+ Sbjct: 1 PLFYIINIIAPCVLISSLVVLVYFLPAQAGGQKCTLSISVLLAQTIFLFLIAQKVPETSL 60 Query: 303 -VKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAE---------KTAKAKND 352 V I YL+ FV + ++ + R P + Sbjct: 61 NVPLIGKYLIFVM-FVSMLIVMNCVIVLNVSLRTPNTHSLSEKIKHLFLGFLPKYLGMQL 119 Query: 353 RSKSES 358 E+ Sbjct: 120 EPSEET 125 >1OED-B nrPDB Length = 250 Score = 98.3 bits (243), Expect = 7e-21, Method: Composition-based stats. Identities = 35/212 (16%), Positives = 73/212 (34%), Gaps = 3/212 (1%) Query: 243 IGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPY 302 ++I+ T +P ILI+IL+ + F++ DA +++L I+ +L +T L + +P+ Sbjct: 1 PLFYIVYTIIPCILISILAILVFYLPPDA-GEKMSLSISALLAVTVFLLLLADKVPETSL 59 Query: 303 -VKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKAKNDRSKSESNRV 361 V I YLM + V +++ + V R P + Sbjct: 60 SVPIIIRYLMFIMILVAFSVIL-SVVVLNLHHRSPNTHTMPNWIRQIFIETLPPFLWIQR 118 Query: 362 DAHGNILLTSLEVHNEMNEVSGGIGDTRNSAISFDNSGIQYRKQSMPREGHGRFLGDRSL 421 + + + N+ + DN+ + + + + E G Sbjct: 119 PVTTPSPDSKPTIISRANDEYFIRKPAGDFVCPVDNARVAVQPERLFSEMKWHLNGLTQP 178 Query: 422 PHKKTHLRRRSSQLKIKIPDLTDVNAIDRWSR 453 L+ +K L + D + Sbjct: 179 VTLPQDLKEAVEAIKYIAEQLESASEFDDLKK 210 >1OED-A nrPDB Length = 227 Score = 94.5 bits (233), Expect = 9e-20, Method: Composition-based stats. Identities = 21/99 (21%), Positives = 45/99 (45%), Gaps = 3/99 (3%) Query: 243 IGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI-P 301 YF++ +P +L + L+ + F++ D+ ++ L I+ +L++T + E +P Sbjct: 1 PLYFVVNVIIPCLLFSFLTGLVFYLPTDS-GEKMTLSISVLLSLTVFLLVIVELIPSTSS 59 Query: 302 YVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 V I Y++ +FV +++ V R P Sbjct: 60 AVPLIGKYMLFTMIFVISSIIITVVVINT-HHRSPSTHT 97 >1OED-C nrPDB Length = 260 Score = 94.1 bits (232), Expect = 1e-19, Method: Composition-based stats. Identities = 18/110 (16%), Positives = 46/110 (41%), Gaps = 9/110 (8%) Query: 243 IGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIPY 302 ++++ P +LI+ L+ ++F++ ++ +++ I+ +L + LP+ Sbjct: 1 PLFYVINFITPCVLISFLASLAFYLPAES-GEKMSTAISVLLAQAVFLLLTSQRLPE--- 56 Query: 303 VKAIDMYLMGCFVFVFLALLEYAFVN----YIFFGRGPQRQKKLAEKTAK 348 A+ + L+G ++ ++L+ VN F R P Sbjct: 57 -TALAVPLIGKYLMFIMSLVTGVIVNCGIVLNFHFRTPSTHVLSTRVKQI 105 >4AOE-A nrPDB Length = 205 Score = 91.0 bits (224), Expect = 1e-18, Method: Composition-based stats. Identities = 36/206 (17%), Positives = 73/206 (35%), Gaps = 9/206 (4%) Query: 38 KETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 +E V ++L + P PV V + I L ++ W+D+ L Sbjct: 6 EEIVKEILGRANPNNIPIVDEQPVKVSFKYSLQDIYTADVGTDQVELGLWLVISWKDRSL 65 Query: 98 AYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITT 157 ++S + +W+P N S ++++R++ DGTV + + T Sbjct: 66 SWSNECTTFNELTLPSKYIWLPHIEVYN---SIGKPGIHSDQLVRVYKDGTVTFVPQYTI 122 Query: 158 TAACMMDLRRYPLDEQ--NCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVE 215 +C ++ EQ CTL+ + Y D+ +T E Q + Sbjct: 123 RFSCALENVTT---EQGAACTLKFGPWTYDVRDLVLD-ESQQVDLTTYAGGERFQLIEAK 178 Query: 216 HRLVSRNVVFATGAYPRLSLSFRLKR 241 ++ + ++ + L K+ Sbjct: 179 QKVNKKTYPCCPQSFEDIELRVTFKK 204 >4ZJS-A nrPDB Length = 230 Score = 88.7 bits (218), Expect = 5e-18, Method: Composition-based stats. Identities = 36/223 (16%), Positives = 70/223 (31%), Gaps = 18/223 (8%) Query: 38 KETVDKLLKGYDIRLRPDF-GGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKR 96 V KL K Y +RP V V + + I + L Y QQ W D Sbjct: 14 TRLVAKLFKDYSSVVRPVEDHRQVVEVTLGFTLQDIVKADSSTNEVDLVYYEQQRWVDYN 73 Query: 97 LAYSGIPLNLTLDNRVA-DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRI 155 L ++ + +W PD + + + ++ + DG+V++ Sbjct: 74 LKWNPDDYGGVKKIHIPAADIWTPDITAYSSTRPV---QVLSPQIAVVTHDGSVMFIPAQ 130 Query: 156 TTTAACMMDLRRYP--LDEQ---NCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQ 210 + C P +D + C ++ S+ Y+ +I+ ++ + Sbjct: 131 RLSFMCD------PTGVDSEEGATCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYE 184 Query: 211 FSIVEHRLVSRNVVFATGAYPR--LSLSFRLKRNIGYFILQTY 251 ++ Y L + FR +R F + Sbjct: 185 ILSATQTRQVQHYSCCPEPYIDVNLVVKFRERRAGNGFFRNLF 227 >2KSR-A nrPDB Length = 164 Score = 84.9 bits (208), Expect = 7e-17, Method: Composition-based stats. Identities = 23/116 (19%), Positives = 45/116 (38%), Gaps = 3/116 (2%) Query: 235 LSFRLKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLR 294 +R ++ + +P +LIT L+ + F++ D ++ L I+ +L +T + Sbjct: 20 FQSNARRKPLFYTINLIIPCVLITSLAILVFYLPSDC-GEKMTLCISVLLALTVFLLLIS 78 Query: 295 ETLPKIPY-VKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQKKLAEKTAKA 349 + +P V + YLM V V +++ V R P A Sbjct: 79 KIVPPTSLDVPLVGKYLMFTMVLVTFSIVTSVCV-LNVHHRSPTTHTPRGGGGYVA 133 >2LLY-A nrPDB Length = 137 Score = 83.3 bits (204), Expect = 2e-16, Method: Composition-based stats. Identities = 22/103 (21%), Positives = 49/103 (47%), Gaps = 3/103 (2%) Query: 239 LKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLP 298 + ++ + +P +LI+ L+ + F++ + ++ L I+ +L++T + E +P Sbjct: 3 AEELPLFYTINLIIPCLLISCLTVLVFYLPSEC-GEKITLCISVLLSLTVFLLLITEIIP 61 Query: 299 KIPYV-KAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 V +I YL+ +FV L+++ FV R P+ Sbjct: 62 STSSVSPSIGEYLLFTMIFVTLSIVITVFV-LNVHHRSPETHT 103 >4AOD-A nrPDB Length = 205 Score = 82.9 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 31/204 (15%), Positives = 68/204 (33%), Gaps = 5/204 (2%) Query: 38 KETVDKLLKGYDIRLRPDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRL 97 E + +L P PV V + I N + + ++ W+D+ L Sbjct: 6 SEILQDVLSRCSPLNIPIEDDQPVKVSFEYSLQKIFRADVENDEVDIGLWTTLVWKDRCL 65 Query: 98 AYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITT 157 + + ++W PD + S +++ R+ DGTV Y ++ Sbjct: 66 NWFNEFTSFKELTVPIAEIWTPDIFIF---DSVGAPEIFSDKLARVSQDGTVTYVPQLKV 122 Query: 158 TAACMMDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHR 217 +C + + C+L+ S+ ++T ++ + Q + Sbjct: 123 RLSCPLADLKLETGV-TCSLKSGSWTHSTQELTLE-VNAKVDLGDYASDTRFQLLNATQQ 180 Query: 218 LVSRNVVFATGAYPRLSLSFRLKR 241 + + Y +LSF ++ Sbjct: 181 VNRKQYPCCPETYEDTTLSFTFRK 204 >4AFG-A nrPDB Length = 230 Score = 82.9 bits (203), Expect = 3e-16, Method: Composition-based stats. Identities = 31/189 (16%), Positives = 64/189 (33%), Gaps = 18/189 (9%) Query: 60 PVCVGMNIDIASIDMVSEVNMDY----TLTMYFQQYWRDKRLAYSG-IPLNLTLDNRVAD 114 V V + + + + + M + T + W D L + P + D Sbjct: 33 KVDVKFGLSLQLLKSIEQRGMGFNSIGTFKAIVKLSWVDTILRWDPEPPFDFQKIEISPD 92 Query: 115 QLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYPLDEQN 174 ++W PD N + + I + +GTVL+ C+ D + Sbjct: 93 EIWTPDIKLFNSVD-LDMTLDRTTQAI-VFSNGTVLWIPPAVLKVLCVSQD-----DVDS 145 Query: 175 CTLEIESYGYTTDDIEFYWRGGDKAVT---GVERIELPQFSIVEHRLVSRNVVFATGAYP 231 C + S+ Y+ D+++ ++ V + +E+ + S +V AY Sbjct: 146 CHFQFGSWVYSVDEVDIHFMDDKAEVLLDFYQDSLEILENSAQRQEVV---YPCCESAYV 202 Query: 232 RLSLSFRLK 240 + L+ Sbjct: 203 EMKYLLALR 211 >2LM2-A nrPDB Length = 137 Score = 79.5 bits (194), Expect = 3e-15, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 44/103 (42%), Gaps = 3/103 (2%) Query: 239 LKRNIGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLP 298 + ++ + +P +LIT L+ + F++ D ++ L I+ +L +T + + +P Sbjct: 3 AEEEPLFYTINLIIPCVLITSLAILVFYLPSDC-GEKMTLCISVLLALTVFLLLISKIVP 61 Query: 299 KIPY-VKAIDMYLMGCFVFVFLALLEYAFVNYIFFGRGPQRQK 340 ++ YLM V V +++ V R P+ Sbjct: 62 PTSSDSPSVGEYLMFTMVLVTFSIVTSVCV-LNVHHRSPETHT 103 >4UM3-P nrPDB Length = 228 Score = 77.2 bits (188), Expect = 1e-14, Method: Composition-based stats. Identities = 38/202 (18%), Positives = 80/202 (39%), Gaps = 13/202 (6%) Query: 48 YDIR--LRPDF---GGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGI 102 Y+IR RPD PV V +++ +I V+E+ + + + Q W D+ LA++ Sbjct: 27 YNIRQTSRPDVIPTQRRPVAVSVSLKFINILEVNEITNEVDVVFWQQTTWSDRTLAWNSS 86 Query: 103 PLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACM 162 + ++ LWVPD N + + ++ + DG V Y I +C Sbjct: 87 HSPDQVSVPISS-LWVPDLAAYN---AISKPEVLTPQLAHVVSDGEVQYTPSIRQRFSCD 142 Query: 163 MDLRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRN 222 + C ++I S+ + + +I + + + +F I++ + Sbjct: 143 VSGVDTESGA-TCRIKIGSWTHHSREISVDPTT-ENSDDSEYFSQYSRFEILDVTQKKNS 200 Query: 223 VVFATGA--YPRLSLSFRLKRN 242 V ++ Y + +S ++ Sbjct: 201 VTYSCCPEAYEDVEVSLNFRKK 222 >1VRY-A nrPDB Length = 76 Score = 76.4 bits (186), Expect = 3e-14, Method: Composition-based stats. Identities = 37/66 (56%), Positives = 48/66 (72%) Query: 273 AARVALGITTVLTMTTINTHLRETLPKIPYVKAIDMYLMGCFVFVFLALLEYAFVNYIFF 332 ARV LGITTVLT+TT ++ R +LPK+ YVKAID++L C +FVF ALLEYA VN++ Sbjct: 2 PARVGLGITTVLTLTTQSSGSRASLPKVSYVKAIDIWLAVCLLFVFSALLEYAAVNFVSR 61 Query: 333 GRGPQR 338 + R Sbjct: 62 KKKKHR 67 >2MAW-A nrPDB Length = 137 Score = 72.9 bits (177), Expect = 3e-13, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 42/91 (46%), Gaps = 2/91 (2%) Query: 244 GYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKIP-Y 302 Y+ L +P +LI+ L+ + F + D+ +++LGIT +L++T + E +P Sbjct: 7 LYYGLNLLIPCVLISALALLVFLLPADS-GEKISLGITVLLSLTVFMLLVAEIMPSTSDS 65 Query: 303 VKAIDMYLMGCFVFVFLALLEYAFVNYIFFG 333 +I Y + V L+++ V Sbjct: 66 SPSIAQYFASTMIIVGLSVVVTVIVLQYHHH 96 >2BJ0-A nrPDB Length = 203 Score = 71.0 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 29/192 (15%), Positives = 67/192 (34%), Gaps = 9/192 (4%) Query: 54 PDFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA 113 P P+ V +N + +I + ++ Q W+ + +L + Sbjct: 18 PLSNNTPLNVSLNFKLMNIVEADTEKDQVEVVLWTQASWKVPYYSSLLSSSSLDQVSLPV 77 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACM-MDLRRYPLDE 172 ++W PD F N + + + + DG+V+Y C +++ P Sbjct: 78 SKMWTPDLSFYN---AIAAPELLSADRVVVSKDGSVIYVPSQRVRFTCDLINVDTEP--G 132 Query: 173 QNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVE--HRLVSRNVVFATGAY 230 C +++ S+ + G + V E + P+F ++ L + Y Sbjct: 133 ATCRIKVGSWTHDNKQFALIT-GEEGVVNIAEYFDSPKFDLLSATQSLNRKKYSCCENMY 191 Query: 231 PRLSLSFRLKRN 242 + ++F ++ Sbjct: 192 DDIEITFAFRKK 203 >3SH1-A nrPDB Length = 230 Score = 71.0 bits (172), Expect = 1e-12, Method: Composition-based stats. Identities = 33/205 (16%), Positives = 64/205 (31%), Gaps = 17/205 (8%) Query: 55 DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVAD 114 P+ V ++ + I + L + QQ W+ L + D R + Sbjct: 32 PTKDDPLTVYLSFSLLDIVKADSSTNEVDLVYWEQQSWKLNSLMWDPNEYGNITDFRTSA 91 Query: 115 -QLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYP--LD 171 +W PD + + V ++ +N ++ G V Y + C P +D Sbjct: 92 ADIWTPDITAYSSTRP-VQVLSPQNALVNSS--GHVQYLPAQRLSFMCD------PTGVD 142 Query: 172 EQ---NCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATG 228 + C ++ S+ Y +I+ ++ + R Sbjct: 143 SEEGATCAVKFGSWSYGGWEIDLKTDTDQVDLSSYYASSKYEILSATQTRSERFYECCKE 202 Query: 229 AYPR--LSLSFRLKRNIGYFILQTY 251 YP L + FR +R F + Sbjct: 203 PYPDVNLVVKFRERRAGNGFFRNLF 227 >2XZ5-A nrPDB Length = 217 Score = 66.8 bits (161), Expect = 2e-11, Method: Composition-based stats. Identities = 30/205 (14%), Positives = 64/205 (31%), Gaps = 17/205 (8%) Query: 55 DFGGPPVCVGMNIDIASIDMVSEVNMDYTLTMYFQQYWRDKRLAYSGIPLNLTLDNRVA- 113 P+ V + + I V + L QQ W+ L + D R + Sbjct: 21 PTKDDPLTVTLGFTLQDIVKVDSSTNEVDLVYCEQQRWKLNSLMWDPNEYGNITDFRTSA 80 Query: 114 DQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGLRITTTAACMMDLRRYP--LD 171 +W PD + + + ++ + DG+V++ + C P +D Sbjct: 81 ADIWTPDITAYSSTRPV---QVLSPQIAVVTHDGSVMFIPAQRLSFMCD------PTGVD 131 Query: 172 EQ---NCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLVSRNVVFATG 228 + C ++ S+ Y+ +I+ ++ + ++ Sbjct: 132 SEEGVTCAVKFGSWVYSGFEIDLKTDTDQVDLSSYYASSKYEILSATQTRQVQHYSCCPE 191 Query: 229 AYPR--LSLSFRLKRNIGYFILQTY 251 Y L + FR +R F + Sbjct: 192 PYIDVNLVVKFRERRAGNGFFRNLF 216 >2LKG-A nrPDB Length = 140 Score = 56.7 bits (135), Expect = 2e-08, Method: Composition-based stats. Identities = 15/93 (16%), Positives = 35/93 (37%), Gaps = 2/93 (2%) Query: 243 IGYFILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRETLPKI-P 301 YF++ P + L+ + F++ D+ ++ + + ++T + E +P Sbjct: 49 PLYFVVNVIEPCKKFSELTGLVFYLPTDS-GEKMTESKSVLKSLTEKLKKIVELIPSTSS 107 Query: 302 YVKAIDMYLMGCFVFVFLALLEYAFVNYIFFGR 334 V I Y++ FV ++ V Sbjct: 108 AVPLIGKYMLFTKEFVESSIKITEEVINTHHRS 140 >4MRS-A nrPDB Length = 614 Score = 32.5 bits (72), Expect = 0.42, Method: Composition-based stats. Identities = 20/111 (18%), Positives = 33/111 (29%), Gaps = 22/111 (19%) Query: 203 VERIELPQFSIVEHRLVSRNVVFATGAYPRLSLSFRLKRN-----------------IGY 245 + + F V +LSL F L R + Y Sbjct: 97 FDNLRNIVFERVGQDATRHLAENVFARLHKLSLRFHLARRTGEVTKVIERGTKSIDTMLY 156 Query: 246 FILQTYMPSILITILSWVSFWINYDASAARVALGITTVLTMTTINTHLRET 296 F+L P+++ V FW+N+ + L T+L + R Sbjct: 157 FLLFNIAPTVIELTAVIVIFWLNFG-----LGLVTATILAVIAYVWTTRTI 202 >5SVA-Z nrPDB Length = 843 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 31/67 (46%), Gaps = 6/67 (8%) Query: 26 QSVNDPGNMSFVKETVDKLLKGYDI---RLRPDFGGPPVCVGMN---IDIASIDMVSEVN 79 Q N FV ++V + + +D RLRPD P+ + + I + S ++E Sbjct: 94 QDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQA 153 Query: 80 MDYTLTM 86 D+ +T+ Sbjct: 154 QDFLVTI 160 >5OQJ-7 nrPDB Length = 843 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 17/67 (25%), Positives = 31/67 (46%), Gaps = 6/67 (8%) Query: 26 QSVNDPGNMSFVKETVDKLLKGYDI---RLRPDFGGPPVCVGMN---IDIASIDMVSEVN 79 Q N FV ++V + + +D RLRPD P+ + + I + S ++E Sbjct: 94 QDTNSDIPADFVPDSVSGMFRSHDFSYLRLRPDHASRPLWISPSDGRIILESFSPLAEQA 153 Query: 80 MDYTLTM 86 D+ +T+ Sbjct: 154 QDFLVTI 160 >3N71-A nrPDB Length = 490 Score = 30.5 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 13/80 (16%), Positives = 30/80 (37%), Gaps = 1/80 (1%) Query: 165 LRRYPLDEQNCTLEIESYGYTTDDIEFYWRGGDKAVTGVERIELPQFSIVEHRLV-SRNV 223 L+ +P Q +++ S+ + + + + + V P +V H + V Sbjct: 155 LQYWPPQSQQFSMQYISHIFGVINCNGFTLSDQRGLQAVGVGIFPNLGLVNHDCWPNCTV 214 Query: 224 VFATGAYPRLSLSFRLKRNI 243 +F G + + F + I Sbjct: 215 IFNNGNHEAVKSMFHTQMRI 234 >5CYO-A nrPDB Length = 274 Score = 30.5 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 16/78 (20%), Positives = 28/78 (35%), Gaps = 3/78 (3%) Query: 93 RDKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTV--- 149 + R+ + I D+ + W P F+ND+ V + PD V Sbjct: 58 KGVRMKLTVIDTPGFGDHINNENCWQPIMKFINDQYEKYLQEEVNINRKKRIPDTRVHCC 117 Query: 150 LYGLRITTTAACMMDLRR 167 LY + T + +D+ Sbjct: 118 LYFIPATGHSLRPLDIEF 135 >6D47-A nrPDB Length = 410 Score = 29.8 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 14/77 (18%), Positives = 30/77 (38%), Gaps = 1/77 (1%) Query: 94 DKRLAYSGIPLNLTLDNRVADQLWVPDTYFLNDKKSFVHGVTVKNRMIRLHPDGTVLYGL 153 D+ L SG ++ + RV ++ P T ++ + + N+ + + DG + Sbjct: 59 DEGLTISGFDYEVSAEVRVPAEIASPGTVLVSGRLLSDITRALPNKPVDFYVDGNRVALT 118 Query: 154 RITTTAACM-MDLRRYP 169 + M + YP Sbjct: 119 CGNARFSLPTMAVEDYP 135 >2DCK-A nrPDB Length = 354 Score = 28.2 bits (61), Expect = 7.9, Method: Composition-based stats. Identities = 19/69 (27%), Positives = 27/69 (39%), Gaps = 5/69 (7%) Query: 29 NDPGNMSFVKETVDKLLKGY--DIR--LRPDFGGPPVCVGMNIDIASIDMVSEVNM-DYT 83 N ++ TVD L++ Y D RP G P + ++ I + N Sbjct: 103 NGNSYLTVYGWTVDPLVEFYIVDSWGTWRPPGGTPKGTINVDGGTYQIYETTRYNQPSIK 162 Query: 84 LTMYFQQYW 92 T FQQYW Sbjct: 163 GTATFQQYW 171 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.314 0.122 0.330 Lambda K H 0.267 0.0374 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,945,061 Number of Sequences: 36641 Number of extensions: 572628 Number of successful extensions: 2181 Number of sequences better than 10.0: 70 Number of HSP's better than 10.0 without gapping: 92 Number of HSP's successfully gapped in prelim test: 24 Number of HSP's that attempted gapping in prelim test: 1849 Number of HSP's gapped (non-prelim): 169 length of query: 473 length of database: 10,336,785 effective HSP length: 101 effective length of query: 372 effective length of database: 6,636,044 effective search space: 2468608368 effective search space used: 2468608368 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.2 bits) S2: 61 (28.2 bits)