BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P28321 (313 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 4ZWN-A nrPDB 650 0.0 6EIC-C nrPDB 85 3e-17 3JWE-A nrPDB 79 2e-15 4DGQ-A nrPDB 40 0.002 3HEA-A nrPDB 40 0.002 2XMZ-A nrPDB 39 0.002 1A8Q-A nrPDB 32 0.32 1HKH-A nrPDB 32 0.34 1JIJ-A nrPDB 32 0.44 1QTR-A nrPDB 32 0.50 3NCO-A nrPDB 30 1.0 5HK8-A nrPDB 30 1.1 1UFO-A nrPDB 30 1.2 5XKS-A nrPDB 30 1.4 5Y6Y-B nrPDB 30 1.6 1R3D-A nrPDB 30 1.6 4HTA-A nrPDB 30 1.8 1AKO-A nrPDB 29 2.7 4LMH-A nrPDB 28 3.9 1V02-A nrPDB 28 4.0 6IDN-A nrPDB 28 7.5 6AVW-A nrPDB 27 8.1 5MB9-A nrPDB 27 8.4 5FSH-A nrPDB 27 9.6 >4ZWN-A nrPDB Length = 334 Score = 650 bits (1677), Expect = 0.0, Method: Compositional matrix adjust. Identities = 310/312 (99%), Positives = 311/312 (99%) Query: 2 APYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMD 61 APYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMD Sbjct: 23 APYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMD 82 Query: 62 HLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWG 121 HLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWG Sbjct: 83 HLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWG 142 Query: 122 HSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRID 181 HSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKF PRVRID Sbjct: 143 HSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFSPRVRID 202 Query: 182 TGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK 241 TGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK Sbjct: 203 TGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK 262 Query: 242 PVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 301 PVIIMHGQDDTINDPKGSEKFI+DCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ Sbjct: 263 PVIIMHGQDDTINDPKGSEKFIRDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 322 Query: 302 WLDKHTTTEAKP 313 WLDKHTTTEAKP Sbjct: 323 WLDKHTTTEAKP 334 >6EIC-C nrPDB Length = 279 Score = 85.1 bits (209), Expect = 3e-17, Method: Compositional matrix adjust. Identities = 79/305 (25%), Positives = 126/305 (41%), Gaps = 39/305 (12%) Query: 10 TTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYE 69 TT E + + Y W V V+L HG GE+ + + L G Sbjct: 3 TTRTERNFAGIGDVRIVYDVWTPDTAPQAV---VVLAHGLGEHARRYDHVAQRLGAAGLV 59 Query: 70 SFTFDQRGAGVTSPGRSKGVTD--EYHV-FNDLEHFVEKNLSECKAKGIPLFMWGHSMGG 126 ++ D RG G S G+ V D EY F+ L + CK + GHSMGG Sbjct: 60 TYALDHRGHG-RSGGKRVLVRDISEYTADFDTLVGIATREYPGCKR-----IVLGHSMGG 113 Query: 127 GICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDL 186 GI Y + ++ + S P + + + + A LL +P + + LD Sbjct: 114 GIVFAYGVERPDNYDL--MVLSAPAVA--AQDLVSPVVAVAAKLLGVVVPGLPVQE-LDF 168 Query: 187 KGITSDKAYRAFLGSDPM----SVP--LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKD 240 I+ D +DP+ VP + + Q+ + M R A A Sbjct: 169 TAISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAP-------------ALT 215 Query: 241 KPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMK 300 P++++HG DD + +GS + ++ SAD +LK YPG H +F+ E ++ N V +D+ Sbjct: 216 APLLVLHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFN-EPER--NQVLDDVV 272 Query: 301 QWLDK 305 WL + Sbjct: 273 AWLTE 277 >3JWE-A nrPDB Length = 320 Score = 79.3 bits (194), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 74/312 (23%), Positives = 132/312 (42%), Gaps = 29/312 (9%) Query: 5 PYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLS 64 P + ++P + A Y+F T + + + HG GE++ L L Sbjct: 24 PRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLM 83 Query: 65 LNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF-NDLEHFVEKNLSECKAKGIPLFMWGHS 123 F D G G + R V ++HVF D+ V+ + G+P+F+ GHS Sbjct: 84 GLDLLVFAHDHVGHGQSEGERM--VVSDFHVFVRDVLQHVDS--MQKDYPGLPVFLLGHS 139 Query: 124 MGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTG 183 MGG I + A + +G + PL++ +P + + A +L LP + + Sbjct: 140 MGGAIAILTAAE--RPGHFAGMVLISPLVLANPESATTFKV-LAAKVLNLVLPNLSLGP- 195 Query: 184 LDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKL-----YKNENNYIQKNFA 238 +D ++ +K SDP+ + G K+ N + +++ Sbjct: 196 IDSSVLSRNKTEVDIYNSDPL-------------ICRAGLKVCFGIQLLNAVSRVERALP 242 Query: 239 K-DKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFN 297 K P +++ G D + D KG+ ++ S DK LK+Y GA H + E +V N+VF+ Sbjct: 243 KLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH-VLHKELPEVTNSVFH 301 Query: 298 DMKQWLDKHTTT 309 ++ W+ + T T Sbjct: 302 EINMWVSQRTAT 313 >4DGQ-A nrPDB Length = 280 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 56/232 (24%), Positives = 89/232 (38%), Gaps = 21/232 (9%) Query: 67 GYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMW-GHSMG 125 G+ D+RG G RS V D + D++H+ + + + G M GHS G Sbjct: 53 GFRVVAHDRRGHG-----RSSQVWDGH----DMDHYADDAAAVVEKLGTHGAMHVGHSTG 103 Query: 126 GGICLNY-ACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGL 184 GG + Y A G+ + I S P +++ + N + + + R L Sbjct: 104 GGEVVRYIARHGERNVSKAVLISSVPPLMVKTSSNPNGTPKSVFDDFQAHVAANRAQFYL 163 Query: 185 DLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK--- 241 D+ R G+ P +Y +RQ M Y + Q +F D Sbjct: 164 DVPAGPFYGYNRP--GAKPSEGVIYNWWRQ--GMMGSTKAQYDGIVAFSQTDFTNDLKGI 219 Query: 242 --PVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKV 291 PV+++HG DD + P + + +L Y GA H I + DKV Sbjct: 220 TIPVLVIHGDDDQVV-PYADSGVLSAKLVKNGKLITYKGAPHGIPTTHADKV 270 >3HEA-A nrPDB Length = 271 Score = 39.7 bits (91), Expect = 0.002, Method: Compositional matrix adjust. Identities = 56/247 (22%), Positives = 94/247 (38%), Gaps = 25/247 (10%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF-NDLEH 101 VL HG+ + M++LS GY + FD+RG G + ++Y F +D+ Sbjct: 22 VLFSHGWPLDADMWEYQMEYLSSRGYRTIAFDRRGFGRSD---QPWTGNDYDTFADDIAQ 78 Query: 102 FVEK-NLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSG---PLIILHPH 157 +E +L E + G SMGGG Y + ++G + G P+ P Sbjct: 79 LIEHLDLKEVT-------LVGFSMGGGDVARYIAR-HGSARVAGLVLLGAVTPIFGQKPD 130 Query: 158 TMYNKPTQIIAPLLAKFLP-RVRI--DTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQ 214 P + A + L R + D GI + + + + + L S + Sbjct: 131 YPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINKGQVVSQGVQTQTLQIALLASLKA 190 Query: 215 IHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELK 274 D + A E ++ D P +++HG D I + + K + ELK Sbjct: 191 TVDCVTAFA-----ETDFRPDMAKIDVPTLVIHGDGDQIVPFETTGKVAAELIKG-AELK 244 Query: 275 LYPGARH 281 +Y A H Sbjct: 245 VYKDAPH 251 >2XMZ-A nrPDB Length = 269 Score = 39.3 bits (90), Expect = 0.002, Method: Compositional matrix adjust. Identities = 32/110 (29%), Positives = 51/110 (46%), Gaps = 11/110 (10%) Query: 27 YMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRS 86 Y F+ TN+V ++ +HGF ++ ++ + N Y T D G G Sbjct: 6 YKFYEANVETNQV---LVFLHGFLSDSRTYHNHIEKFTDN-YHVITIDLPGHG-----ED 56 Query: 87 KGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQG 136 + DE F+ + +++ L + K K I LF G+SMGG + L YA G Sbjct: 57 QSSMDETWNFDYITTLLDRILDKYKDKSITLF--GYSMGGRVALYYAING 104 >1A8Q-A nrPDB Length = 274 Score = 32.0 bits (71), Expect = 0.32, Method: Compositional matrix adjust. Identities = 26/69 (37%), Positives = 38/69 (55%), Gaps = 9/69 (13%) Query: 240 DKPVIIMHGQDDTIN--DPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKV-FNTVF 296 D P +++HG DD + D G K Q P+A ELK+Y G+ H I + DK FN Sbjct: 212 DIPTLVVHGDDDQVVPIDATG-RKSAQIIPNA--ELKVYEGSSHGIAMVPGDKEKFN--- 265 Query: 297 NDMKQWLDK 305 D+ ++L+K Sbjct: 266 RDLLEFLNK 274 >1HKH-A nrPDB Length = 279 Score = 32.0 bits (71), Expect = 0.34, Method: Compositional matrix adjust. Identities = 65/272 (23%), Positives = 104/272 (38%), Gaps = 51/272 (18%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTD-EYHVFNDLEH 101 V+LIHG+ R L GY T+D+RG G G SK T +Y F H Sbjct: 26 VVLIHGYPLDGHSWERQTRELLAQGYRVITYDRRGFG----GSSKVNTGYDYDTFAADLH 81 Query: 102 FVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKN--EISGYIGSGPLIILHPHTM 159 V + L + + G SMG G Y + H+ +++ P ++ Sbjct: 82 TVLETLDLRD-----VVLVGFSMGTGELARYVARYGHERVAKLAFLASLEPFLVQRDDNP 136 Query: 160 YNKPTQIIAPL--------LAKFLPRVRIDTGLD--LKGITSDKA----YRAFLGSDPMS 205 P ++ + A F + LD L S++A + +GS P++ Sbjct: 137 EGVPQEVFDGIEAAAKGDRFAWFTDFYKNFYNLDENLGSRISEQAVTGSWNVAIGSAPVA 196 Query: 206 ----VPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHG-QDDTINDPKGSE 260 VP + I DF ++ A KP +I+HG +D+ + + Sbjct: 197 AYAVVPAW-----IEDFRSD-----------VEAVRAAGKPTLILHGTKDNILPIDATAR 240 Query: 261 KFIQDCPSAD-KELKLYPGARHSIFSLETDKV 291 +F Q P AD E++ GA H + D+V Sbjct: 241 RFHQAVPEADYVEVE---GAPHGLLWTHADEV 269 >1JIJ-A nrPDB Length = 420 Score = 31.6 bits (70), Expect = 0.44, Method: Compositional matrix adjust. Identities = 18/65 (27%), Positives = 30/65 (46%), Gaps = 4/65 (6%) Query: 241 KPVIIMHGQDDTINDPKG--SEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFND 298 +P++++ G I DP G E+ +Q DK ++ H+IF TD V + Sbjct: 66 RPIVLIGGGTGMIGDPSGKSEERVLQTEEQVDKNIEGISKQMHNIFEFGTDH--GAVLVN 123 Query: 299 MKQWL 303 + WL Sbjct: 124 NRDWL 128 >1QTR-A nrPDB Length = 317 Score = 31.6 bits (70), Expect = 0.50, Method: Compositional matrix adjust. Identities = 20/66 (30%), Positives = 28/66 (42%), Gaps = 6/66 (9%) Query: 68 YESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGG 127 Y+ FDQRG G + P S +H+ D+E E E ++G S G Sbjct: 64 YKVLLFDQRGCGRSRPHASLDNNTTWHLVADIERLREMAGVE------QWLVFGGSWGST 117 Query: 128 ICLNYA 133 + L YA Sbjct: 118 LALAYA 123 >3NCO-A nrPDB Length = 320 Score = 30.4 bits (67), Expect = 1.0, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 44/93 (47%), Gaps = 11/93 (11%) Query: 36 TNEVRGRVLLIHGFGEYTKI-QFRLMDH----LSLNGYESFTFDQRGAGVTSPGRSKGVT 90 TN R ++ + + Y+ + + +L+D +S + YE F F +GA SP GV Sbjct: 168 TNPSRIVIIDVPNWSNYSYVRELKLVDDKNIIVSFHYYEPFNFTHQGAEWVSPTLPIGVK 227 Query: 91 DE---YHVFNDLEHFVEKNLSE-CKAKGIPLFM 119 E + V HF K +SE K +P+F+ Sbjct: 228 WEGKDWEVEQIRNHF--KYVSEWAKKNNVPIFL 258 >5HK8-A nrPDB Length = 298 Score = 30.4 bits (67), Expect = 1.1, Method: Compositional matrix adjust. Identities = 28/120 (23%), Positives = 51/120 (42%), Gaps = 15/120 (12%) Query: 44 LLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFV 103 + +HG ++L L G++S + D GAG++ + D VF+ ++ Sbjct: 50 VFVHGASHGAWCWYKLTTLLDAAGFKSTSVDLTGAGIS-------LIDSNIVFDSDQY-- 100 Query: 104 EKNLSECKAKGIP---LFMWGHSMGGGICLNYACQGKHKNEISGYIGSG---PLIILHPH 157 + L + P + + GHS+GGG C+ K ++ Y+ + P I PH Sbjct: 101 NRPLFSLLSDLPPHHKVILVGHSIGGGSVTEALCKFTDKISMAIYLAASMVQPGSIPSPH 160 >1UFO-A nrPDB Length = 238 Score = 30.0 bits (66), Expect = 1.2, Method: Compositional matrix adjust. Identities = 27/113 (23%), Positives = 46/113 (40%), Gaps = 6/113 (5%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFD--QRGAGVTSPGRSKG---VTDEYHVFN 97 +L +HG + L+ + G+ FD + G P SK V + Y V Sbjct: 27 LLALHGLQGSKEHILALLPGYAERGFLLLAFDAPRHGEREGPPPSSKSPRYVEEVYRVAL 86 Query: 98 DLEHFVEKNLSECKAK-GIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSG 149 + + E + + G+PLF+ G S+G + +G + +IGSG Sbjct: 87 GFKEEARRVAEEAERRFGLPLFLAGGSLGAFVAHLLLAEGFRPRGVLAFIGSG 139 >5XKS-A nrPDB Length = 256 Score = 30.0 bits (66), Expect = 1.4, Method: Compositional matrix adjust. Identities = 53/207 (25%), Positives = 79/207 (38%), Gaps = 36/207 (17%) Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNK 162 VE K + +F+ G SMGG + L A +H EI G I + N Sbjct: 77 VEAGYEWLKNRCGTIFVTGLSMGGTLTLYMA---EHHPEICG--------IAPINAAINM 125 Query: 163 PTQIIAPLLAKFLPRVRIDTGLDLK--GITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQ 220 P A LPR G D+K G+ + AY + S RQI M+ Sbjct: 126 PALAGALAGVGDLPRFLDAIGSDIKKPGV-KELAYEKTPAA---------SIRQIVQLME 175 Query: 221 RGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGAR 280 R K + + I P I+ +D + P + SADK+L P + Sbjct: 176 R----VKTDLHKITC------PAILFCSDEDHVVPPDNAPFIYDHIASADKKLVRLPDSY 225 Query: 281 HSIFSLETD--KVFNTVFNDMKQWLDK 305 H + +L+ D K+ +T K+ D+ Sbjct: 226 H-VATLDNDRQKIIDTSLAFFKKHADR 251 >5Y6Y-B nrPDB Length = 326 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 2/87 (2%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 VL +HGF E + LS GY + D RG G T S +H+ DL Sbjct: 27 VLFLHGFPELWYSWRHQILALSSRGYRAVAPDLRGYGDTEAPVSISSYTGFHIVGDLIAL 86 Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGIC 129 ++ L + WG +G +C Sbjct: 87 ID--LLGVDQVFLVAHDWGAIIGWYLC 111 >1R3D-A nrPDB Length = 264 Score = 29.6 bits (65), Expect = 1.6, Method: Compositional matrix adjust. Identities = 23/94 (24%), Positives = 42/94 (44%), Gaps = 7/94 (7%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 V+L+HG ++ HL+ + T D G G T+P R D F + Sbjct: 19 VVLVHGLLGSGADWQPVLSHLARTQCAALTLDLPGHG-TNPERH---CDN---FAEAVEM 71 Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQG 136 +E+ + +P+ + G+S+GG + ++ QG Sbjct: 72 IEQTVQAHVTSEVPVILVGYSLGGRLIMHGLAQG 105 >4HTA-A nrPDB Length = 288 Score = 29.6 bits (65), Expect = 1.8, Method: Compositional matrix adjust. Identities = 15/44 (34%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Query: 40 RGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSP 83 ++L HGFG + L+ HL ++ Y +D GAG T+P Sbjct: 35 EATIVLGHGFGTDQSVWKHLVPHL-VDDYRVVLYDNMGAGTTNP 77 >1AKO-A nrPDB Length = 268 Score = 28.9 bits (63), Expect = 2.7, Method: Compositional matrix adjust. Identities = 10/24 (41%), Positives = 16/24 (66%) Query: 223 AKLYKNENNYIQKNFAKDKPVIIM 246 A+ Y+N NY++ +D PV+IM Sbjct: 126 AQFYQNLQNYLETELKRDNPVLIM 149 >4LMH-A nrPDB Length = 760 Score = 28.5 bits (62), Expect = 3.9, Method: Compositional matrix adjust. Identities = 32/113 (28%), Positives = 45/113 (39%), Gaps = 17/113 (15%) Query: 55 IQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKA-- 112 I+F M H G E TFD GA V +P + G + + + H+ +K ++C A Sbjct: 262 IEFTYMIHAIHKGGERHTFDATGAQVPAPYKIIGYGGKVIDYGKV-HYPQKPAADCAACH 320 Query: 113 ---KGIP----LFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHT 158 G P LF S N AC G H + S + S + H T Sbjct: 321 VEGAGAPANADLFKADLS-------NQACIGCHTEKPSAHHSSTDCMACHNAT 366 >1V02-A nrPDB Length = 565 Score = 28.5 bits (62), Expect = 4.0, Method: Compositional matrix adjust. Identities = 22/82 (26%), Positives = 38/82 (46%), Gaps = 8/82 (9%) Query: 45 LIHGFGEYTKIQFR-----LMDHLSLNGYESFTFDQRGAGVTSPGR-SKGVTDEYHVFND 98 +I + ++ K+ F + + L+ N E+F G GV +PGR S GV+ N Sbjct: 213 IIKDYTDFAKVCFEKFGKTVKNWLTFNEPETFCSVSYGTGVLAPGRCSPGVSCAVPTGNS 272 Query: 99 LE--HFVEKNLSECKAKGIPLF 118 L + V NL A+ + ++ Sbjct: 273 LSEPYIVAHNLLRAHAETVDIY 294 >6IDN-A nrPDB Length = 272 Score = 27.7 bits (60), Expect = 7.5, Method: Compositional matrix adjust. Identities = 12/26 (46%), Positives = 18/26 (69%), Gaps = 3/26 (11%) Query: 102 FVEKNLSECKAKGIPLFMWGHSMGGG 127 F+ +S CK+KGI +F+ S+GGG Sbjct: 59 FLSSEISYCKSKGIKVFL---SLGGG 81 >6AVW-A nrPDB Length = 230 Score = 27.3 bits (59), Expect = 8.1, Method: Compositional matrix adjust. Identities = 16/49 (32%), Positives = 24/49 (48%), Gaps = 4/49 (8%) Query: 238 AKDKPVIIMHGQDDTI---NDPKGSEKFIQDCPSADKELKLYPGARHSI 283 AK P++ HG DD + + + F+++ E K YPG HSI Sbjct: 149 AKKTPILWSHGTDDRMVLFEAGQAALPFLKEA-GVTCEFKAYPGLGHSI 196 >5MB9-A nrPDB Length = 590 Score = 27.3 bits (59), Expect = 8.4, Method: Compositional matrix adjust. Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 5/93 (5%) Query: 208 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCP 267 +Y +HD+ G L K ++ K F K P G D +P+ K + Sbjct: 240 MYTILATVHDYEYHGIALDKVLIDHFSKEFLKKNP-----GAKDPRENPRSLAKLRLEAE 294 Query: 268 SADKELKLYPGARHSIFSLETDKVFNTVFNDMK 300 S + L A S+ SL F + N ++ Sbjct: 295 STKRALSRSTNASFSVESLIDGLDFASTINRLR 327 >5FSH-A nrPDB Length = 467 Score = 27.3 bits (59), Expect = 9.6, Method: Compositional matrix adjust. Identities = 12/18 (66%), Positives = 14/18 (77%) Query: 169 PLLAKFLPRVRIDTGLDL 186 P A+FLPR+R DTG DL Sbjct: 85 PESARFLPRLRQDTGKDL 102 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 4ZWN-A nrPDB 467 e-132 3JWE-A nrPDB 317 4e-87 6EIC-C nrPDB 272 2e-73 4DGQ-A nrPDB 234 3e-62 3HEA-A nrPDB 232 1e-61 Sequences not found previously or not previously below threshold: 1A88-A nrPDB 166 1e-41 1A8S-A nrPDB 162 1e-40 1A8Q-A nrPDB 132 2e-31 3FOB-A nrPDB 121 5e-28 4IQ4-A nrPDB 117 8e-27 1HKH-A nrPDB 114 7e-26 1BRO-A nrPDB 113 1e-25 4RNC-A nrPDB 71 5e-13 3KXP-A nrPDB 68 5e-12 4UHD-A nrPDB 66 2e-11 2E3J-A nrPDB 62 3e-10 5Y6Y-B nrPDB 58 5e-09 2Y6V-A nrPDB 55 3e-08 4HTA-A nrPDB 55 4e-08 1M33-A nrPDB 55 4e-08 1XRN-A nrPDB 54 5e-08 2XMZ-A nrPDB 53 1e-07 4NMW-A nrPDB 53 2e-07 5AOA-A nrPDB 52 3e-07 4FBL-A nrPDB 52 3e-07 2WUG-A nrPDB 52 4e-07 6AP7-A nrPDB 51 5e-07 1U2E-A nrPDB 51 5e-07 4IH4-A nrPDB 51 8e-07 3HSS-A nrPDB 50 1e-06 1QTR-A nrPDB 49 2e-06 5HK8-A nrPDB 48 6e-06 5XKS-A nrPDB 46 1e-05 3RLI-A nrPDB 46 2e-05 1AZW-A nrPDB 45 4e-05 1CR6-A nrPDB 44 5e-05 4Y2Y-A nrPDB 44 7e-05 5EGN-A nrPDB 44 9e-05 3KSR-A nrPDB 43 1e-04 1UFO-A nrPDB 43 2e-04 6AVW-A nrPDB 41 5e-04 3C5W-P nrPDB 41 8e-04 1R1D-A nrPDB 41 8e-04 3WMR-A nrPDB 41 8e-04 6FKX-A nrPDB 40 0.001 4EB0-A nrPDB 40 0.001 5YHP-A nrPDB 39 0.002 2RON-A nrPDB 39 0.002 2YYS-A nrPDB 39 0.003 3FCY-A nrPDB 39 0.004 1R3D-A nrPDB 38 0.004 4GDM-A nrPDB 37 0.009 3V48-A nrPDB 37 0.013 4G5X-A nrPDB 36 0.028 1Q0R-A nrPDB 35 0.054 2ECF-A nrPDB 34 0.073 5UGZ-A nrPDB 34 0.10 5YP1-A nrPDB 33 0.14 3CN7-A nrPDB 33 0.15 5DWD-A nrPDB 33 0.17 1Y7H-A nrPDB 33 0.18 3V1K-A nrPDB 33 0.18 3BF8-A nrPDB 33 0.19 4XJV-A nrPDB 33 0.21 5LZ5-A nrPDB 32 0.31 4CCW-A nrPDB 32 0.38 1Z68-A nrPDB 31 0.49 2EDA-A nrPDB 31 0.58 3EMV-A nrPDB 31 0.59 3O0D-A nrPDB 31 0.74 1THT-A nrPDB 31 0.77 3AZQ-A nrPDB 31 0.80 5YAL-A nrPDB 30 1.1 2PPL-A nrPDB 30 1.1 6FVJ-A nrPDB 30 1.3 3D2A-A nrPDB 30 1.4 3WYD-A nrPDB 29 2.0 2C4K-A nrPDB 29 3.6 1JFR-A nrPDB 28 4.7 2OCI-A nrPDB 28 4.9 6IGR-A nrPDB 28 7.7 >4ZWN-A nrPDB Length = 334 Score = 467 bits (1200), Expect = e-132, Method: Composition-based stats. Identities = 310/312 (99%), Positives = 311/312 (99%) Query: 2 APYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMD 61 APYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMD Sbjct: 23 APYPYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMD 82 Query: 62 HLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWG 121 HLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWG Sbjct: 83 HLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWG 142 Query: 122 HSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRID 181 HSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKF PRVRID Sbjct: 143 HSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFSPRVRID 202 Query: 182 TGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK 241 TGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK Sbjct: 203 TGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK 262 Query: 242 PVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 301 PVIIMHGQDDTINDPKGSEKFI+DCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ Sbjct: 263 PVIIMHGQDDTINDPKGSEKFIRDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 322 Query: 302 WLDKHTTTEAKP 313 WLDKHTTTEAKP Sbjct: 323 WLDKHTTTEAKP 334 >3JWE-A nrPDB Length = 320 Score = 317 bits (812), Expect = 4e-87, Method: Composition-based stats. Identities = 74/312 (23%), Positives = 131/312 (41%), Gaps = 29/312 (9%) Query: 5 PYKVQTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLS 64 P + ++P + A Y+F T + + + HG GE++ L L Sbjct: 24 PRRTPQSIPYQDLPHLVNADGQYLFCRYWKPTGTPKALIFVSHGAGEHSGRYEELARMLM 83 Query: 65 LNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF-NDLEHFVEKNLSECKAKGIPLFMWGHS 123 F D G G + R V ++HVF D+ V+ + G+P+F+ GHS Sbjct: 84 GLDLLVFAHDHVGHGQSEGERM--VVSDFHVFVRDVLQHVDS--MQKDYPGLPVFLLGHS 139 Query: 124 MGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTG 183 MGG I + A + +G + PL++ +P + + A +L LP + + Sbjct: 140 MGGAIAILTAAE--RPGHFAGMVLISPLVLANPESATTFKV-LAAKVLNLVLPNLSLGP- 195 Query: 184 LDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAK-----LYKNENNYIQKNFA 238 +D ++ +K SDP+ + G K N + +++ Sbjct: 196 IDSSVLSRNKTEVDIYNSDPL-------------ICRAGLKVCFGIQLLNAVSRVERALP 242 Query: 239 K-DKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFN 297 K P +++ G D + D KG+ ++ S DK LK+Y GA H + E +V N+VF+ Sbjct: 243 KLTVPFLLLQGSADRLCDSKGAYLLMELAKSQDKTLKIYEGAYH-VLHKELPEVTNSVFH 301 Query: 298 DMKQWLDKHTTT 309 ++ W+ + T T Sbjct: 302 EINMWVSQRTAT 313 >6EIC-C nrPDB Length = 279 Score = 272 bits (694), Expect = 2e-73, Method: Composition-based stats. Identities = 78/306 (25%), Positives = 126/306 (41%), Gaps = 39/306 (12%) Query: 10 TTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYE 69 TT E + + Y W V V+L HG GE+ + + L G Sbjct: 3 TTRTERNFAGIGDVRIVYDVWTPDTAPQAV---VVLAHGLGEHARRYDHVAQRLGAAGLV 59 Query: 70 SFTFDQRGAGVTSPGRSKGVTD--EYHV-FNDLEHFVEKNLSECKAKGIPLFMWGHSMGG 126 ++ D RG G + G+ V D EY F+ L + CK + GHSMGG Sbjct: 60 TYALDHRGHGRS-GGKRVLVRDISEYTADFDTLVGIATREYPGCKR-----IVLGHSMGG 113 Query: 127 GICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDL 186 GI Y + ++ + S P + + + + A LL +P + + LD Sbjct: 114 GIVFAYGVERPDNYDL--MVLSAPAVAA--QDLVSPVVAVAAKLLGVVVPGLPVQE-LDF 168 Query: 187 KGITSDKAYRAFLGSDPM----SVP--LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKD 240 I+ D +DP+ VP + + Q+ + M R A A Sbjct: 169 TAISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAP-------------ALT 215 Query: 241 KPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMK 300 P++++HG DD + +GS + ++ SAD +LK YPG H +F+ E ++ N V +D+ Sbjct: 216 APLLVLHGTDDRLIPIEGSRRLVECVGSADVQLKEYPGLYHEVFN-EPER--NQVLDDVV 272 Query: 301 QWLDKH 306 WL + Sbjct: 273 AWLTER 278 >4DGQ-A nrPDB Length = 280 Score = 234 bits (597), Expect = 3e-62, Method: Composition-based stats. Identities = 62/284 (21%), Positives = 103/284 (36%), Gaps = 26/284 (9%) Query: 21 DGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGV 80 DG + Y W ++ + HG+ + + G+ D+RG G Sbjct: 12 DGVEIFYKDWGPRDA-----KVIHFHHGWPLSSDDWDAQLLFFVNKGFRVVAHDRRGHG- 65 Query: 81 TSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMW-GHSMGGGICLNY-ACQGKH 138 RS V D + D++H+ + + + G M GHS GGG + Y A G+ Sbjct: 66 ----RSSQVWDGH----DMDHYADDAAAVVEKLGTHGAMHVGHSTGGGEVVRYIARHGER 117 Query: 139 KNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAF 198 + I S P +++ + N + + + R LD+ R Sbjct: 118 NVSKAVLISSVPPLMVKTSSNPNGTPKSVFDDFQAHVAANRAQFYLDVPAGPFYGYNRP- 176 Query: 199 LGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDK-----PVIIMHGQDDTI 253 G+ P +Y +RQ M Y + Q +F D PV+++HG DD + Sbjct: 177 -GAKPSEGVIYNWWRQ--GMMGSTKAQYDGIVAFSQTDFTNDLKGITIPVLVIHGDDDQV 233 Query: 254 NDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFN 297 P + + +L Y GA H I + DKV + Sbjct: 234 V-PYADSGVLSAKLVKNGKLITYKGAPHGIPTTHADKVNADLLE 276 >3HEA-A nrPDB Length = 271 Score = 232 bits (591), Expect = 1e-61, Method: Composition-based stats. Identities = 58/285 (20%), Positives = 104/285 (36%), Gaps = 29/285 (10%) Query: 20 FDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAG 79 F +++ G+ + VL HG+ + M++LS GY + FD+RG G Sbjct: 3 FVAKDGTQIYFKDW-GSGKP---VLFSHGWPLDADMWEYQMEYLSSRGYRTIAFDRRGFG 58 Query: 80 VTSPGRSKGVTDEYHVF-NDLEHFVEK-NLSECKAKGIPLFMWGHSMGGGICLNYACQGK 137 + ++Y F +D+ +E +L E + G SMGGG Y + Sbjct: 59 RSD---QPWTGNDYDTFADDIAQLIEHLDLKEVT-------LVGFSMGGGDVARYIAR-H 107 Query: 138 HKNEISGYIGSG---PLIILHPHTMYNKPTQIIAPLLAKFLP-RVRI--DTGLDLKGITS 191 ++G + G P+ P P + A + L R + D GI Sbjct: 108 GSARVAGLVLLGAVTPIFGQKPDYPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINK 167 Query: 192 DKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDD 251 + + + + + L S + D + A E ++ D P +++HG D Sbjct: 168 GQVVSQGVQTQTLQIALLASLKATVDCVTAFA-----ETDFRPDMAKIDVPTLVIHGDGD 222 Query: 252 TINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVF 296 I + + K + ELK+Y A H ++ + Sbjct: 223 QIVPFETTGKVAAELIKG-AELKVYKDAPHGFAVTHAQQLNEDLL 266 >1A88-A nrPDB Length = 275 Score = 166 bits (419), Expect = 1e-41, Method: Composition-based stats. Identities = 51/276 (18%), Positives = 92/276 (33%), Gaps = 26/276 (9%) Query: 21 DGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGV 80 DG Y W ++G V+ HG+ M +GY D+RG G Sbjct: 7 DGTNIFYKDWGPRDG-----LPVVFHHGWPLSADDWDNQMLFFLSHGYRVIAHDRRGHGR 61 Query: 81 TSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMW-GHSMGGGICLNYACQG-KH 138 + D+ +D++ + + +A + + GHS GGG Y + Sbjct: 62 S---------DQPSTGHDMDTYAADVAALTEALDLRGAVHIGHSTGGGEVARYVARAEPG 112 Query: 139 KNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAF 198 + + + + P +++ T + + L R +D+ R Sbjct: 113 RVAKAVLVSAVPPVMVKSDTNPDGLPLEVFDEFRAALAANRAQFYIDVPSGPFYGFNRE- 171 Query: 199 LGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFA-----KDKPVIIMHGQDDTI 253 G+ + + Q M Y+ + + +F D PV++ HG DD + Sbjct: 172 -GATVSQGLIDHWWLQ--GMMGAANAHYECIAAFSETDFTDDLKRIDVPVLVAHGTDDQV 228 Query: 254 NDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETD 289 P A+ LK Y G H + S + Sbjct: 229 V-PYADAAPKSAELLANATLKSYEGLPHGMLSTHPE 263 >1A8S-A nrPDB Length = 273 Score = 162 bits (410), Expect = 1e-40, Method: Composition-based stats. Identities = 50/278 (17%), Positives = 91/278 (32%), Gaps = 28/278 (10%) Query: 21 DGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGV 80 DG + Y W G+ + ++ HG+ M L+ GY D+RG G Sbjct: 7 DGTQIYYKDW----GSGQP---IVFSHGWPLNADSWESQMIFLAAQGYRVIAHDRRGHGR 59 Query: 81 TSPGRSKGVTDEYHVF-NDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNY-ACQGKH 138 +S ++ + +DL +E ++G S GGG Y G Sbjct: 60 SS---QPWSGNDMDTYADDLAQLIEH------LDLRDAVLFGFSTGGGEVARYIGRHGTA 110 Query: 139 KNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAF 198 + +G I + P ++L + + + R DL + Sbjct: 111 RVAKAGLISAVPPLMLKTEANPGGLPMEVFDGIRQASLADRSQLYKDLASGPFFGFNQP- 169 Query: 199 LGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFA-----KDKPVIIMHGQDDTI 253 G+ + + + Q Y + + +F D P +++HG D + Sbjct: 170 -GAKSSAGMVDWFWLQ--GMAAGHKNAYDCIKAFSETDFTEDLKKIDVPTLVVHGDADQV 226 Query: 254 NDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKV 291 + S LK+Y GA H + D++ Sbjct: 227 VPIEASG-IASAALVKGSTLKIYSGAPHGLTDTHKDQL 263 >1A8Q-A nrPDB Length = 274 Score = 132 bits (332), Expect = 2e-31, Method: Composition-based stats. Identities = 50/273 (18%), Positives = 90/273 (32%), Gaps = 21/273 (7%) Query: 21 DGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGV 80 DG + Y W V+ IHG+ + + GY D+RG G Sbjct: 7 DGVEIFYKDWGQGRP-------VVFIHGWPLNGDAWQDQLKAVVDAGYRGIAHDRRGHGH 59 Query: 81 TSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNY-ACQGKHK 139 ++P V D Y F+ + N + + HSMGGG Y G + Sbjct: 60 STP-----VWDGYD-FDTFAD--DLNDLLTDLDLRDVTLVAHSMGGGELARYVGRHGTGR 111 Query: 140 NEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFL 199 + + + P +++ + + L + R D A R Sbjct: 112 LRSAVLLSAIPPVMIKSDKNPDGVPDEVFDALKNGVLTERSQFWKD-TAEGFFSANRPG- 169 Query: 200 GSDPMSVPLYGSFRQIHDFMQRGAKLYK--NENNYIQKNFAKDKPVIIMHGQDDTINDPK 257 + + ++ G + ++ + D P +++HG DD + Sbjct: 170 NKVTQGNKDAFWYMAMAQTIEGGVRCVDAFGYTDFTEDLKKFDIPTLVVHGDDDQVVPID 229 Query: 258 GSEKFIQDCPSADKELKLYPGARHSIFSLETDK 290 + + + ELK+Y G+ H I + DK Sbjct: 230 ATGR-KSAQIIPNAELKVYEGSSHGIAMVPGDK 261 >3FOB-A nrPDB Length = 281 Score = 121 bits (302), Expect = 5e-28, Method: Composition-based stats. Identities = 47/271 (17%), Positives = 89/271 (32%), Gaps = 24/271 (8%) Query: 33 QNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDE 92 +GT + V+LIHG+ + + L GY T+D+RG G +S E Sbjct: 23 DHGTGKP---VVLIHGWPLSGRSWEYQVPALVEAGYRVITYDRRGFGKSS---QPWEGYE 76 Query: 93 YHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYAC-QGKHKNEISGYIGSGPL 151 Y F + + + + + + G SMGGG Y G + E + G+ P Sbjct: 77 YDTFTS-----DLHQLLEQLELQNVTLVGFSMGGGEVARYISTYGTDRIEKVVFAGAVPP 131 Query: 152 IILHPHTMYNKPTQIIA-PLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMS----- 205 + + R+ + R L S+ Sbjct: 132 YLYKSEDHPEGALDDATIETFKSGVINDRLAFLDEFTKGFFAAGDRTDLVSESFRLYNWD 191 Query: 206 VPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQD 265 + S + D + +K ++ + + P +I+HG D + S K + Sbjct: 192 IAAGASPKGTLDCITAFSK-----TDFRKDLEKFNIPTLIIHGDSDATVPFEYSGKLTHE 246 Query: 266 CPSADKELKLYPGARHSIFSLETDKVFNTVF 296 + ++ L G H + + + + Sbjct: 247 AIP-NSKVALIKGGPHGLNATHAKEFNEALL 276 >4IQ4-A nrPDB Length = 456 Score = 117 bits (292), Expect = 8e-27, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 81/273 (29%), Gaps = 18/273 (6%) Query: 28 MFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSK 87 + +GT V+LIHGF R L GY T+D+RG G +S Sbjct: 15 DLYYEDHGTGTP---VVLIHGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSS---QP 68 Query: 88 GVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQ-GKHKNEISGYI 146 +Y F + N + G SMG G Y G + ++ Sbjct: 69 TTGYDYDTFA-----ADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAAVAFL 123 Query: 147 GSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRA-FLGSDPMS 205 S +L + + V+ D G +D LG+ Sbjct: 124 ASLEPFLLKTDDNPDG--AAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISE 181 Query: 206 VPLYGSFRQIHDFMQRGAKLYKNE--NNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFI 263 + S+ A ++ D P +I+HG D + + + Sbjct: 182 EAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVF 241 Query: 264 QDCPSADKELKLYPGARHSIFSLETDKVFNTVF 296 + E GA H + ++V + Sbjct: 242 HKALPS-AEYVEVEGAPHGLLWTHAEEVNTALL 273 >1HKH-A nrPDB Length = 279 Score = 114 bits (284), Expect = 7e-26, Method: Composition-based stats. Identities = 56/267 (20%), Positives = 87/267 (32%), Gaps = 24/267 (8%) Query: 33 QNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDE 92 G+ + V+LIHG+ R L GY T+D+RG G +S + Sbjct: 19 DQGSGQP---VVLIHGYPLDGHSWERQTRELLAQGYRVITYDRRGFGGSS---KVNTGYD 72 Query: 93 YHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQ-GKHKNEISGYIGSGPL 151 Y F H V + L + + G SMG G Y + G + ++ S Sbjct: 73 YDTFAADLHTVLETLDLRD-----VVLVGFSMGTGELARYVARYGHERVAKLAFLASLEP 127 Query: 152 IILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRA-FLGSDPMSVPLYG 210 ++ Q + + R D + LGS + G Sbjct: 128 FLVQRDDNPEGVPQEVFDGIEAAAKGDRFAWFTDFY---KNFYNLDENLGSRISEQAVTG 184 Query: 211 SFRQIHDFMQ--RGAKLYKNENNYIQKNFAK---DKPVIIMHGQDDTINDPKGS-EKFIQ 264 S+ A + ++ A KP +I+HG D I + +F Q Sbjct: 185 SWNVAIGSAPVAAYAVVPAWIEDFRSDVEAVRAAGKPTLILHGTKDNILPIDATARRFHQ 244 Query: 265 DCPSADKELKLYPGARHSIFSLETDKV 291 P AD GA H + D+V Sbjct: 245 AVPEAD--YVEVEGAPHGLLWTHADEV 269 >1BRO-A nrPDB Length = 277 Score = 113 bits (281), Expect = 1e-25, Method: Composition-based stats. Identities = 49/273 (17%), Positives = 82/273 (30%), Gaps = 18/273 (6%) Query: 28 MFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSK 87 + +GT + V+LIHGF R L GY T+D+RG G +S Sbjct: 14 DLYYEDHGTGQP---VVLIHGFPLSGHSWERQSAALLDAGYRVITYDRRGFGQSS---QP 67 Query: 88 GVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQ-GKHKNEISGYI 146 +Y F + N + G SMG G Y G + ++ Sbjct: 68 TTGYDYDTFA-----ADLNTVLETLDLQDAVLVGFSMGTGEVARYVSSYGTARIAKVAFL 122 Query: 147 GSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRA-FLGSDPMS 205 S +L + + V+ D G +D LG+ Sbjct: 123 ASLEPFLLKTDDNPDG--AAPQEFFDGIVAAVKADRYAFYTGFFNDFYNLDENLGTRISE 180 Query: 206 VPLYGSFRQIHDFMQRGAKLYKNE--NNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFI 263 + S+ A ++ D P +I+HG D + + + Sbjct: 181 EAVRNSWNTAASGGFFAAAAAPTTWYTDFRADIPRIDVPALILHGTGDRTLPIENTARVF 240 Query: 264 QDCPSADKELKLYPGARHSIFSLETDKVFNTVF 296 + E GA H + ++V + Sbjct: 241 HKALPS-AEYVEVEGAPHGLLWTHAEEVNTALL 272 >4RNC-A nrPDB Length = 310 Score = 71.0 bits (172), Expect = 5e-13, Method: Composition-based stats. Identities = 43/285 (15%), Positives = 93/285 (32%), Gaps = 25/285 (8%) Query: 15 LQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFD 74 + + DG Y N ++L+HG+ + ++ + Y D Sbjct: 25 REAVSVDGTSIVYRV--TGNSAGTP---LVLLHGWAQSSQCWGEQVLADLAADYRLIAVD 79 Query: 75 QRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGI--PLFMWGHSMGGGICLNY 132 RG G + S ++D ++ + A+G+ + G S GG + +Y Sbjct: 80 LRGHGYSDAPESG--------YDDSANWAGDVAAVLAAEGVTENAILLGWSYGGLVICDY 131 Query: 133 ACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITS- 191 ++G + G + + + + D ++ + + Sbjct: 132 LA-AHGTGAVAGAVLVGAITSIG-RGEKGGKVGSAMR--SAVPGAMSEDPREAIRALGAF 187 Query: 192 -DKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQD 250 + G S L+G + A L+ + + D PV+++HG D Sbjct: 188 GNALTGPPEGKGAASQALFGYSLSTRP--RVRAALFNRAVGHDELLRNLDIPVLVLHGTD 245 Query: 251 DTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTV 295 D++ D + + P + + G H F + + + V Sbjct: 246 DSVVDVSAGKHAEELIPKSQASY--WVGCNHGPFVEDPTRFVSEV 288 >3KXP-A nrPDB Length = 314 Score = 68.0 bits (164), Expect = 5e-12, Method: Composition-based stats. Identities = 46/261 (17%), Positives = 85/261 (32%), Gaps = 17/261 (6%) Query: 42 RVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEH 101 +L HG + + LM LS + + DQRG G++ + ++Y +D+ Sbjct: 70 LMLFFHGITSNSAVFEPLMIRLSDR-FTTIAVDQRGHGLSDKPETGYEANDYA--DDIAG 126 Query: 102 FVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYN 161 + + GHS+G + A + I P I Sbjct: 127 LIRTLARG------HAILVGHSLGARNSVTAAAKYPDLVRSVVAIDFTPYIETEALDALE 180 Query: 162 KPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKA-YRAFLGSDPMSVPLYGSFRQIHDFMQ 220 + L + V I +D RA G P+ L M Sbjct: 181 ARVNAGSQLFED-IKAVEAYLAGRYPNIPADAIRIRAESGYQPVDGGLRP--LASSAAMA 237 Query: 221 RGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGAR 280 + A+ ++ + + KPV+I+ G+ + K + P D + + PGA Sbjct: 238 QTARGLRS--DLVPAYRDVTKPVLIVRGESSKLVSAAALAKTSRLRP--DLPVVVVPGAD 293 Query: 281 HSIFSLETDKVFNTVFNDMKQ 301 H + + + + N + Sbjct: 294 HYVNEVSPEITLKAITNFIDA 314 >4UHD-A nrPDB Length = 282 Score = 65.7 bits (158), Expect = 2e-11, Method: Composition-based stats. Identities = 51/286 (17%), Positives = 95/286 (33%), Gaps = 39/286 (13%) Query: 33 QNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDE 92 GT VLL+HGF + + L + + D RG G + GV Sbjct: 22 DTGTGLP---VLLVHGFPLDRTMWKAQREEL-CDEFRVIVPDLRGFGESQV--IPGVA-- 73 Query: 93 YHVFNDLEHFVEKNLSECKAKGIPLFMW--GHSMGGGICLNYACQGKHKNEISGYIGSGP 150 +E + C G+ + G SMGG + +A + + ++G I Sbjct: 74 -----TMEAMADDLAGLCNHLGLTGKIVLGGLSMGGYVAFAFARKYRD--RLAGLILCD- 125 Query: 151 LIILHPHTMYNKPTQIIAPLLAKFL-PRVRIDTGLDL----KGITSDKAYRAFLGSDPMS 205 P + K + + P + + + + +S Sbjct: 126 -TRARPDSPEAKENRRRVAERVRREGPGFIAEEMIPRLCCESTFRNHPEVIEKIRQMILS 184 Query: 206 VPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQD 265 P G +R + + + A P +++ GQ D I+ P+ E + Sbjct: 185 APPEGVAAAALGMAER-----PDSTDLLP---ALSCPTLVLVGQFDAISPPEEMEAMART 236 Query: 266 CPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQWLDKHTTTEA 311 P + + + P A H + ++V +++WL + TEA Sbjct: 237 IPQS--QFVVIPDAGHLPPMEQPERVTQA----IREWL-RKVHTEA 275 >2E3J-A nrPDB Length = 356 Score = 61.8 bits (148), Expect = 3e-10, Method: Composition-based stats. Identities = 27/138 (19%), Positives = 49/138 (35%), Gaps = 8/138 (5%) Query: 16 QYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQ 75 Q + + + ++ V+L+HGF E + L+ GY DQ Sbjct: 3 QVHRILNCRGTRIHAVADSPPDQQGPLVVLLHGFPESWYSWRHQIPALAGAGYRVVAIDQ 62 Query: 76 RGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQ 135 RG G +S R + + D+ ++ +E F+ GH G + +A Sbjct: 63 RGYGRSSKYRVQKAYRIKELVGDVVGVLDSYGAE------QAFVVGHDWGAPVAWTFA-- 114 Query: 136 GKHKNEISGYIGSGPLII 153 H + +G +G Sbjct: 115 WLHPDRCAGVVGISVPFA 132 >5Y6Y-B nrPDB Length = 326 Score = 58.3 bits (139), Expect = 5e-09, Method: Composition-based stats. Identities = 30/115 (26%), Positives = 42/115 (36%), Gaps = 7/115 (6%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 VL +HGF E + LS GY + D RG G T S +H+ DL Sbjct: 27 VLFLHGFPELWYSWRHQILALSSRGYRAVAPDLRGYGDTEAPVSISSYTGFHIVGDLIAL 86 Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPH 157 ++ L +F+ H G I Y C + S PL+ P+ Sbjct: 87 ID--LLGVDQ----VFLVAHDW-GAIIGWYLCTFHPDRVKAYVCLSVPLLHRDPN 134 >2Y6V-A nrPDB Length = 398 Score = 55.3 bits (131), Expect = 3e-08, Method: Composition-based stats. Identities = 53/346 (15%), Positives = 98/346 (28%), Gaps = 59/346 (17%) Query: 2 APYPYKVQTTVPELQYENFDGAKFGYMFW----PVQNGTNEVRGRVLLIHGFGEYTKIQF 57 A +P Q+T D + Y + + R ++ +HG G + Sbjct: 15 ASWPRAPQST-----LCATDRLELTYDVYTSAERQRRSRTATRLNLVFLHGSGMSKVVWE 69 Query: 58 RLMDHLSLNGYE-------SFTFDQRGAGVTSPGRSKGVTDEYHVFN---DLEHFVEKNL 107 + L E DQ G ++ + ++ + D+ L Sbjct: 70 YYLPRLVAADAEGNYAIDKVLLIDQVNHGDSAVRNRGRLGTNFNWIDGARDVLKIATCEL 129 Query: 108 SECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILH----------PH 157 + + GHSMGG L AC N I P++I P Sbjct: 130 GSIDSHPALNVVIGHSMGGFQAL--ACDVLQPNLFHLLILIEPVVITRKAIGAGRPGLPP 187 Query: 158 TMYNKPTQIIAPL-------------LAKFLPRVRIDTGLDLKGITS--DKAYRAFLGSD 202 P + L K++ T + + + D G D Sbjct: 188 DSPQIPENLYNSLRLKTCDHFANESEYVKYMRNGSFFTNAHSQILQNIIDFERTKASGDD 247 Query: 203 PMSVPLYGSFRQIHDF-----MQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPK 257 P+ Q + MQ A + +++K I + G P+ Sbjct: 248 EDGGPVRTKMEQAQNLLCYMNMQTFAPFLISNVKFVRKR------TIHIVGARSNWCPPQ 301 Query: 258 GSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQWL 303 + + L + PG H + D V + + + +++ Sbjct: 302 --NQLFLQKTLQNYHLDVIPGGSHLVNVEAPDLVIERINHHIHEFV 345 >4HTA-A nrPDB Length = 288 Score = 54.9 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 35/218 (16%), Positives = 69/218 (31%), Gaps = 16/218 (7%) Query: 37 NEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF 96 ++L HGFG + L+ HL ++ Y +D GAG T+P ++ + Sbjct: 32 GSGEATIVLGHGFGTDQSVWKHLVPHL-VDDYRVVLYDNMGAGTTNPDYF-----DFDRY 85 Query: 97 NDLEHFVEKNLSECKAKGIPL-FMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILH 155 ++LE + ++ + I GHS+ I + + I + P + Sbjct: 86 SNLEGYSFDLIAILEDLKIESCIFVGHSVSAMIGVLASLNRPDLFSKIVMISASPRYVND 145 Query: 156 PHTMYNKPTQIIAPLLAKFLPR--------VRIDTGLDLKGITSDKAYRAFLGSDPMSVP 207 + + L + G D+ I + R P + Sbjct: 146 VDYQGGFEQEDLNQLFEAIRSNYKAWCLGFAPLAVGGDMDSIAVQEFSRTLFNMRP-DIA 204 Query: 208 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVII 245 L M++ + +Q PV++ Sbjct: 205 LSVGQTIFQSDMRQILPFVTVPCHILQSVKDLAVPVVV 242 >1M33-A nrPDB Length = 258 Score = 54.9 bits (130), Expect = 4e-08, Method: Composition-based stats. Identities = 33/258 (12%), Positives = 74/258 (28%), Gaps = 19/258 (7%) Query: 33 QNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDE 92 + ++L+HG+G ++ + + LS + + D G G + + Sbjct: 6 WQTKGQGNVHLVLLHGWGLNAEVWRCIDEELSSH-FTLHLVDLPGFGRSRGFGA------ 58 Query: 93 YHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLI 152 + + + G S+GG + A + + S P Sbjct: 59 -------LSLADMAEAVLQQAPDKAIWLGWSLGGLVASQIALTHPERVRALVTVASSPCF 111 Query: 153 ILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSF 212 ++A + L + T + + A + + + Sbjct: 112 SAR-DEWPGIKPDVLAGFQQQ-LSDDQQRTVERFLALQTMGTETARQDARALKKTVLALP 169 Query: 213 RQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKE 272 D + G ++ K + Q P + ++G D + K D E Sbjct: 170 MPEVDVLNGGLEILKT-VDLRQPLQNVSMPFLRLYGYLDGLVPRKVVPML--DKLWPHSE 226 Query: 273 LKLYPGARHSIFSLETDK 290 ++ A H+ F + Sbjct: 227 SYIFAKAAHAPFISHPAE 244 >1XRN-A nrPDB Length = 293 Score = 54.5 bits (129), Expect = 5e-08, Method: Composition-based stats. Identities = 49/301 (16%), Positives = 101/301 (33%), Gaps = 38/301 (12%) Query: 17 YENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQR 76 EN+ Y+++ + E + +++ +HG + + ++ G +DQ Sbjct: 6 IENYAKVNGIYIYYKLCKAPEE-KAKLMTMHGGPGMSHDYLLSLRDMTKEGITVLFYDQF 64 Query: 77 GAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQG 136 G G + T +Y V + L +F+ G S GG + L YA + Sbjct: 65 GCGRSEEPDQSKFTIDYGVEE------AEALRSKLFGNEKVFLMGSSYGGALALAYAVKY 118 Query: 137 KHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVR-IDTGLDLKGITSDKAY 195 + + G I SG L + + + L+ + + R G + Y Sbjct: 119 QD--HLKGLIVSGGL------SSVPLTVKEMNRLIDELPAKYRDAIKKYGSSGSYENPEY 170 Query: 196 RAFLG--------------SDPMSVPLYGSFRQIHDFM----QRGAKLYKNENNYIQKNF 237 + + + + Y R ++ M Q + + K Sbjct: 171 QEAVNYFYHQHLLRSEDWPPEVLKSLEYAERRNVYRIMNGPNQFTITGTIKDWDITDKIS 230 Query: 238 AKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFN 297 A P +I G+ D + + I + + EL ++ H + E + +N + + Sbjct: 231 AIKIPTLITVGEYDEVTP--NVARVIHEKIAGS-ELHVFRDCSH-LTMWEDREGYNKLLS 286 Query: 298 D 298 D Sbjct: 287 D 287 >2XMZ-A nrPDB Length = 269 Score = 53.3 bits (126), Expect = 1e-07, Method: Composition-based stats. Identities = 44/272 (16%), Positives = 95/272 (34%), Gaps = 19/272 (6%) Query: 27 YMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRS 86 Y F+ TN+V ++ +HGF ++ ++ + N Y T D G G Sbjct: 6 YKFYEANVETNQV---LVFLHGFLSDSRTYHNHIEKFTDN-YHVITIDLPGHGE-DQSSM 60 Query: 87 KGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYI 146 + F+ + +++ L K K + ++G+SMGG + L YA G Sbjct: 61 DETWN----FDYITTLLDRILD--KYKDKSITLFGYSMGGRVALYYAINGHIPISNLILE 114 Query: 147 GSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSV 206 + P I + + + A + + + D + + ++ + Sbjct: 115 STSPGIKEEANQLERRLVDD-ARAKVLDIAGIEL-FVNDWEKLPLFQSQLELPVEIQHQI 172 Query: 207 PLYGSFRQIHDFMQRGAKLYKNEN-NYIQKNFAKDKPVIIMHGQ-DDTINDPKGSEKFIQ 264 + H + + N + P +I+ G+ D+ ++K Sbjct: 173 RQQRLSQSPHKMAKALRDYGTGQMPNLWPRLKEIKVPTLILAGEYDEKFVQI--AKKMAN 230 Query: 265 DCPSADKELKLYPGARHSIFSLETDKVFNTVF 296 P++ +L G H+I ++D+ + Sbjct: 231 LIPNSKCKLISATG--HTIHVEDSDEFDTMIL 260 >4NMW-A nrPDB Length = 259 Score = 52.9 bits (125), Expect = 2e-07, Method: Composition-based stats. Identities = 34/261 (13%), Positives = 77/261 (29%), Gaps = 21/261 (8%) Query: 28 MFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSK 87 W E ++L+HG+G ++ + + L + + D G G +S Sbjct: 6 DIW--WQTYGEGNCHLVLLHGWGLNAEVWHCIREELGSH-FTLHLVDLPGYGRSSGF--- 59 Query: 88 GVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIG 147 ++ V KN + G S+GG + A + + + Sbjct: 60 ----GAMTLEEMTAQVAKNAPD------QAIWLGWSLGGLVASQMALTHPERVQALVTVA 109 Query: 148 SGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVP 207 S P +I+ + + T + + A + + Sbjct: 110 SSPCFSAR-EGWPGIKPEILGGFQQQLSDDFQ-RTVERFLALQTLGTETARQDARTLKSV 167 Query: 208 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCP 267 + + + G ++ K + + + P + ++G D + K P Sbjct: 168 VLAQPMPDVEVLNGGLEILKT-VDLREALKNVNMPFLRLYGYLDGLVPRKIVPLLDTLWP 226 Query: 268 SADKELKLYPGARHSIFSLET 288 + ++ A H+ F Sbjct: 227 HSTSQIMA--KAAHAPFISHP 245 >5AOA-A nrPDB Length = 286 Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 46/288 (15%), Positives = 78/288 (27%), Gaps = 49/288 (17%) Query: 4 YPYKVQTTVPELQYENFDGAKFGYMFWPV--QNGTNEVRGRVLL-IHGFGEYTKIQFR-L 59 YP ++ ++ Y+ D + + V G+ + QFR Sbjct: 8 YPPEMPGAEVKV-YKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQ 66 Query: 60 MDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFM 119 ++ + G + D R + + V D + +E + Sbjct: 67 CEYFAGRGMVAMAADYRVGSRHNVKVADCVADAKSAIRWVRQHA----AELGVDPQKIVA 122 Query: 120 WGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVR 179 G S GG ++ P + A L L R Sbjct: 123 SGGSAGG--------------HLAACTVMVPDLEAPEEDHTISSQANAAILFNPVLILSR 168 Query: 180 IDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAK 239 + ++ R LG++P +V Y R G Sbjct: 169 EGLKDHVPRQDWEERLRERLGTEPKAVSPYHHIR-------AGLP--------------- 206 Query: 240 DKPVIIMHGQDDTINDPKGSEKFIQDCPSADK--ELKLYPGARHSIFS 285 P+II HG D + F + A EL + GA H F+ Sbjct: 207 --PMIIFHGTADNTVPFETIRLFAEAMKKAGNRCELVPFEGAAHGFFN 252 >4FBL-A nrPDB Length = 281 Score = 52.2 bits (123), Expect = 3e-07, Method: Composition-based stats. Identities = 53/252 (21%), Positives = 87/252 (34%), Gaps = 36/252 (14%) Query: 40 RGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDL 99 R VL+ HGF + L + + GY T G G T + ++ D+ Sbjct: 51 RIGVLVSHGFTGSPQSMRFLAEGFARAGYTVATPRLTGHGTTPAEMAASTASDWTA--DI 108 Query: 100 EHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTM 159 + C LFM G SMGG + + A G+ +G + Sbjct: 109 VAAMRWLEERCDV----LFMTGLSMGGALTVWAA--GQFPERFAGIM------------P 150 Query: 160 YNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDF- 218 N ++ +P LA D +L GI SD G ++ P+ H Sbjct: 151 INAALRMESPDLAAL--AFNPDAPAELPGIGSD---IKAEGVKELAYPVTPVPAIKHLIT 205 Query: 219 MQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPG 278 + A++ P +I+ ++D + P E S +KEL Sbjct: 206 IGAVAEMLLPRVK---------CPALIIQSREDHVVPPHNGELIYNGIGSTEKELLWLEN 256 Query: 279 ARHSIFSLETDK 290 + H + +L+ DK Sbjct: 257 SYH-VATLDNDK 267 >2WUG-A nrPDB Length = 291 Score = 51.8 bits (122), Expect = 4e-07, Method: Composition-based stats. Identities = 36/251 (14%), Positives = 81/251 (32%), Gaps = 14/251 (5%) Query: 43 VLLIHGFGEYTKIQFRLMDHLS--LNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLE 100 V+L+HG G +++ + DQ G G + E+ FN Sbjct: 39 VVLLHGGGPGAASWTNFSRNIAVLARHFHVLAVDQPGYGHSDK------RAEHGQFNRYA 92 Query: 101 HFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMY 160 K L + G + + G+++GGG + +A + + GP + Sbjct: 93 AMALKGLFDQLGLG-RVPLVGNALGGGTAVRFALD--YPARAGRLVLMGPGGLSINLFAP 149 Query: 161 NKPTQIIAPLLAKFLP-RVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFM 219 + + P R ++ L + + + S Sbjct: 150 DPTEGVKRLSKFSVAPTRENLEAFLRVMVYDKNLITPELVDQRFALASTPESLTATRAMG 209 Query: 220 QRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGA 279 + A ++ + +PV+++ G++D +N G+ + +L ++ Sbjct: 210 KSFAGADFEAGMMWREVYRLRQPVLLIWGREDRVNPLDGA--LVALKTIPRAQLHVFGQC 267 Query: 280 RHSIFSLETDK 290 H + + D+ Sbjct: 268 GHWVQVEKFDE 278 >6AP7-A nrPDB Length = 269 Score = 51.4 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 37/212 (17%), Positives = 66/212 (31%), Gaps = 17/212 (8%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 ++L HGFG R++ L Y +D AG +P ++ + L+ + Sbjct: 23 LVLAHGFGTDQSAWNRILPFF-LRDYRVVLYDLVCAGSVNPDFF-----DFRRYTTLDPY 76 Query: 103 VEKNLSECKAKGI-PLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYN 161 V+ L A GI GHS+ I + + + IG+ P + Sbjct: 77 VDDLLHILDALGIDQCAYVGHSVSAMIGILASIRRPELFSKLILIGASPRFLNDEDYHGG 136 Query: 162 KPTQIIAPLLAKFLPR--------VRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFR 213 I + + + G D+ + R P + L+ S Sbjct: 137 FEQGEIEKVFSAMEANYEAWVNGFAPLAVGADVPAAVR-EFSRTLFNMRP-DITLFVSRT 194 Query: 214 QIHDFMQRGAKLYKNENNYIQKNFAKDKPVII 245 + M+ L K + Q P + Sbjct: 195 VFNSDMRGVLGLVKVPCHIFQTARDHSVPASV 226 >1U2E-A nrPDB Length = 289 Score = 51.4 bits (121), Expect = 5e-07, Method: Composition-based stats. Identities = 39/266 (14%), Positives = 81/266 (30%), Gaps = 31/266 (11%) Query: 43 VLLIHGFGEYTKIQ---FRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDL 99 V+L+HG G R +D L GY D G G + + G + + Sbjct: 39 VVLLHGSGPGATGWANFSRNIDPLVEAGYRVILLDCPGWGKSDSVVNSGSRSDLNA---- 94 Query: 100 EHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTM 159 ++ + + I + G+SMGG + + + + +G G Sbjct: 95 -RILKSVVDQLDIAKIH--LLGNSMGGHSSVAFTLKWPERVGKLVLMGGG---------- 141 Query: 160 YNKPTQIIAPLLAKFLPRVRI---DTGLDLKGITSDKAYRAFLG-SDPMSVPLYGSFRQI 215 + P+ + + R+ ++ + D +D + + Sbjct: 142 -TGGMSLFTPMPTEGIKRLNQLYRQPTIENLKLMMDIFVFDTSDLTDALFEARLNNMLSR 200 Query: 216 HDFMQRGAKLY----KNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADK 271 D ++ K K ++ + +I+ G++D + + A Sbjct: 201 RDHLENFVKSLEANPKQFPDFGPRLAEIKAQTLIVWGRNDRFVPMDAGLRLLS--GIAGS 258 Query: 272 ELKLYPGARHSIFSLETDKVFNTVFN 297 EL ++ H D V N Sbjct: 259 ELHIFRDCGHWAQWEHADAFNQLVLN 284 >4IH4-A nrPDB Length = 267 Score = 50.6 bits (119), Expect = 8e-07, Method: Composition-based stats. Identities = 42/255 (16%), Positives = 78/255 (30%), Gaps = 25/255 (9%) Query: 37 NEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVF 96 + L HGFG ++ + + N Y +D AG +P +++ + Sbjct: 16 GTGDRILFLAHGFGTDQSAWHLILPYFTQN-YRVVLYDLVCAGSVNPDYF-----DFNRY 69 Query: 97 NDLEHFVEKNLSECKAKGIP-LFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILH 155 L+ +V+ L+ + GI GHS+ I + + + IG P + Sbjct: 70 TTLDPYVDDLLNIVDSLGIQNCAYVGHSVSAMIGIIASIRRPELFSKLILIGFSPRFLND 129 Query: 156 PHTMYNKPTQIIAPLLAKFLPR--------VRIDTGLDLKGITSDKAYRAFLGSDPMSVP 207 I + + + G D+ + R P + Sbjct: 130 EDYHGGFEEGEIEKVFSAMEANYEAWVHGFAPLAVGADVPAAVR-EFSRTLFNMRP-DIS 187 Query: 208 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMH------GQDDTINDPKGSEK 261 L+ S + ++ L + IQ P + G D T+ K Sbjct: 188 LFVSRTVFNSDLRGVLGLVRVPTCVIQTAKDVSVPASVAEYLRSHLGGDTTVETLKTEGH 247 Query: 262 FIQDCPSADKELKLY 276 Q SA +L + Sbjct: 248 LPQ--LSAPAQLAQF 260 >3HSS-A nrPDB Length = 293 Score = 50.2 bits (118), Expect = 1e-06, Method: Composition-based stats. Identities = 43/273 (15%), Positives = 67/273 (24%), Gaps = 35/273 (12%) Query: 33 QNGTNEVRGRVLLIHGFGEYTKIQF-RLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTD 91 NGT + V+ I G G + + GY TFD RG G T Sbjct: 39 DNGTGDP---VVFIAGRGGAGRTWHPHQVPAFLAAGYRCITFDNRGIGATENA------- 88 Query: 92 EYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPL 151 F + P + G SMG I + + Sbjct: 89 --EGFTTQTMVADTAALIETLDIAPARVVGVSMGAFIAQELMVVAPELVSSAVLM----- 141 Query: 152 IILHPHTMYNKPTQIIAPLLAKFLP-----RVRIDTGLDLKGITSDKAYRAFLGSDPMSV 206 K V++ D + + R L D Sbjct: 142 -------ATRGRLDRARQFFNKAEAELYDSGVQLPPTYDARARLLENFSRKTLNDDVAVG 194 Query: 207 PLYGSFRQIHDFMQRGAKLYKN---ENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFI 263 F G + + + N + PV+++ DD + P + Sbjct: 195 DWIAMFSMWPIKSTPGLRCQLDCAPQTNRLPAYRNIAAPVLVIGFADDVVTPPYLGREVA 254 Query: 264 QDCPSADKELKLYPGARHSIFSLETDKVFNTVF 296 P + P A H F + V + Sbjct: 255 DALP--NGRYLQIPDAGHLGFFERPEAVNTAML 285 >1QTR-A nrPDB Length = 317 Score = 49.5 bits (116), Expect = 2e-06, Method: Composition-based stats. Identities = 48/292 (16%), Positives = 92/292 (31%), Gaps = 42/292 (14%) Query: 20 FDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAG 79 D ++W + N + IHG G I Y+ FDQRG G Sbjct: 19 LDTGDGHRIYWELSGNPNGKPA--VFIHG-GPGGGISPHHRQLFDPERYKVLLFDQRGCG 75 Query: 80 VTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHK 139 + P S +H+ D+E + ++ + ++G S G + L YA H Sbjct: 76 RSRPHASLDNNTTWHLVADIERL--REMAGVEQ----WLVFGGSWGSTLALAYA--QTHP 127 Query: 140 NEISGYIGSGPLIILHPH---TMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYR 196 +S + G + + ++ + L + D D+ + Sbjct: 128 ERVSEMVLRGIFTLRKQRLHWYYQDGASRFFPEKWERVLSILSDDERKDVIAAYRQRLTS 187 Query: 197 AFLGSDPMSVPLYGSFR-QIHDFMQRGAKLYKNENNY-------------------IQKN 236 A + L+ + + + E+++ Sbjct: 188 ADPQVQLEAAKLWSVWEGETVTLLPSRESASFGEDDFALAFARIENHYFTHLGFLESDDQ 247 Query: 237 FAKDKPVI------IMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHS 282 ++ P+I I+HG+ D + + + P + EL + GA HS Sbjct: 248 LLRNVPLIRHIPAVIVHGRYDMACQVQNAWDLAKAWP--EAELHIVEGAGHS 297 >5HK8-A nrPDB Length = 298 Score = 47.9 bits (112), Expect = 6e-06, Method: Composition-based stats. Identities = 44/262 (16%), Positives = 92/262 (35%), Gaps = 20/262 (7%) Query: 35 GTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYH 94 G E + +HG ++L L G++S + D GAG++ + + Sbjct: 41 GGAEPVIHFVFVHGASHGAWCWYKLTTLLDAAGFKSTSVDLTGAGISLID--SNIVFDSD 98 Query: 95 VFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIIL 154 +N + +L + + GHS+GGG C+ K ++ Y+ + ++ Sbjct: 99 QYNRPLFSLLSDLP----PHHKVILVGHSIGGGSVTEALCKFTDKISMAIYLAAS---MV 151 Query: 155 HPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLK---GITSDKAYRAFLGSD-PMSVPLYG 210 P ++ + I + + + G D + + R + S P+ Sbjct: 152 QPGSIPSPHLSNI-HVGEEDIWEYTYGEGTDKPPTGVLMKPEFIRHYYYSQSPLEDVTLS 210 Query: 211 SFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSAD 270 S M+ L K A+ P + + D + D + +++ P + Sbjct: 211 SKLLRPAPMRAFQDLDK----LPPNPEAEKVPRVYIKTAKDNLFDSVRQDLLVENWPPS- 265 Query: 271 KELKLYPGARHSIFSLETDKVF 292 +L + + HS F +F Sbjct: 266 -QLYVLEDSDHSAFFSVPTTLF 286 >5XKS-A nrPDB Length = 256 Score = 46.4 bits (108), Expect = 1e-05, Method: Composition-based stats. Identities = 52/264 (19%), Positives = 78/264 (29%), Gaps = 38/264 (14%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 +L++HGF + L + GY +G G K D Sbjct: 23 ILVLHGFTGSPQSMRPLGEAYHEAGYTVCGPRLKGHGTHYEDMEK------TTCQDWIDS 76 Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNK 162 VE K + +F+ G SMGG + L A G P+ Sbjct: 77 VEAGYEWLKNRCGTIFVTGLSMGGTLTLYMAEHHPE------ICGIAPINAAINMPALAG 130 Query: 163 PTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRG 222 + LPR G D I P S RQI M+R Sbjct: 131 ALAGVGD-----LPRFLDAIGSD---IKKPGVKELAYEKTPA-----ASIRQIVQLMERV 177 Query: 223 AKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHS 282 P I+ +D + P + SADK+L P + H Sbjct: 178 KT----------DLHKITCPAILFCSDEDHVVPPDNAPFIYDHIASADKKLVRLPDSYH- 226 Query: 283 IFSLETDKVFNTVFNDMKQWLDKH 306 + +L+ D+ + + + KH Sbjct: 227 VATLDNDR--QKIIDTSLAFFKKH 248 >3RLI-A nrPDB Length = 270 Score = 46.0 bits (107), Expect = 2e-05, Method: Composition-based stats. Identities = 54/268 (20%), Positives = 80/268 (29%), Gaps = 45/268 (16%) Query: 15 LQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFD 74 QY GA+ Y N G VLL+HGF L + + GY Sbjct: 23 EQYPVLSGAEPFY-------AENGPVG-VLLVHGFTGTPHSMRPLAEAYAKAGYTVCLPR 74 Query: 75 QRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYAC 134 +G G E F+D VE+ K + +F+ G SMGG + L A Sbjct: 75 LKGHGTHYEDM------ERTTFHDWVASVEEGYGWLKQRCQTIFVTGLSMGGTLTLYLAE 128 Query: 135 QGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKA 194 G P+ + + P LPR G DL + Sbjct: 129 HHPD------ICGIVPI-----NAAVDIPAIAAGMTGGGELPRYLDSIGSDL----KNPD 173 Query: 195 YRA-FLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTI 253 + P S Q+ M + P +I +D + Sbjct: 174 VKELAYEKTPT-----ASLLQLARLMAQTKAKLDRIV----------CPALIFVSDEDHV 218 Query: 254 NDPKGSEKFIQDCPSADKELKLYPGARH 281 P ++ Q S +KE+ + H Sbjct: 219 VPPGNADIIFQGISSTEKEIVRLRNSYH 246 >1AZW-A nrPDB Length = 313 Score = 45.2 bits (105), Expect = 4e-05, Method: Composition-based stats. Identities = 53/310 (17%), Positives = 98/310 (31%), Gaps = 46/310 (14%) Query: 9 QTTVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGY 68 P Q + F N + V+++HG G ++ Y Sbjct: 6 PEITPYQQGSLKVDDRHTLYFEQCGNPHGKP---VVMLHG-GPGGGCNDKMRRFHDPAKY 61 Query: 69 ESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGI 128 FDQRG+G ++P + + D+E ++G S G + Sbjct: 62 RIVLFDQRGSGRSTPHADLVDNTTWDLVADIERLRTH--LGVDRWQ----VFGGSWGSTL 115 Query: 129 CLNYACQGKHKNEISGYIGSGPLIILH-------------------PHTMYNKPTQIIAP 169 L YA H +++ + G ++ H + P A Sbjct: 116 ALAYA--QTHPQQVTELVLRGIFLLRRFELEWFYQEGASRLFPDAWEHYLNAIPPVERAD 173 Query: 170 LLAKFLPRVRIDTGLDLKGITSDKAYRAF------------LGSDPMSVPLYGSFRQIHD 217 L++ F R+ D + G + L + + H Sbjct: 174 LMSAFHRRLTSDDEATRLAAAKAWSVWEGATSFLHVDEDFVTGHEDAHFALAFARIENHY 233 Query: 218 FMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYP 277 F+ G +++ A D P +I+HG+ D + + + + P A +L++ P Sbjct: 234 FVNGGFFEVEDQLLRDAHRIA-DIPGVIVHGRYDVVCPLQSAWDLHKAWPKA--QLQISP 290 Query: 278 GARHSIFSLE 287 + HS F E Sbjct: 291 ASGHSAFEPE 300 >1CR6-A nrPDB Length = 554 Score = 44.5 bits (103), Expect = 5e-05, Method: Composition-based stats. Identities = 27/124 (21%), Positives = 45/124 (36%), Gaps = 9/124 (7%) Query: 45 LIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVE 104 L HGF E + L+ G+ D +G G +S S +EY +E + Sbjct: 261 LCHGFPESWFSWRYQIPALAQAGFRVLAIDMKGYGDSS---SPPEIEEYA----MELLCK 313 Query: 105 KNLSECKAKGIPLFM-WGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKP 163 + ++ GIP + GH G + N A + + + P + P K Sbjct: 314 EMVTFLDKLGIPQAVFIGHDWAGVMVWNMALFYPERVR-AVASLNTPFMPPDPDVSPMKV 372 Query: 164 TQII 167 + I Sbjct: 373 IRSI 376 >4Y2Y-A nrPDB Length = 561 Score = 44.5 bits (103), Expect = 7e-05, Method: Composition-based stats. Identities = 25/119 (21%), Positives = 44/119 (36%), Gaps = 9/119 (7%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 V L HGF E + L+ GY D +G G +S + +EY +E Sbjct: 261 VCLCHGFPESWYSWRYQIPALAQAGYRVLAMDMKGYGESS---APPEIEEYC----MEVL 313 Query: 103 VEKNLSECKAKGIPLFM-WGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMY 160 ++ ++ G+ + GH GG + A + + + P I +P+ Sbjct: 314 CKEMVTFLDKLGLSQAVFIGHDWGGMLVWYMALFYPERVR-AVASLNTPFIPANPNMSP 371 >5EGN-A nrPDB Length = 271 Score = 44.1 bits (102), Expect = 9e-05, Method: Composition-based stats. Identities = 45/284 (15%), Positives = 87/284 (30%), Gaps = 32/284 (11%) Query: 21 DGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGV 80 DG K Y + G ++ +H F I + + + D RG G Sbjct: 7 DGVKIYYDSY----GEGVP---IVFLHPFSTNGGIWYFQTFPFAQTNH-VIVIDHRGHGR 58 Query: 81 TSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFM-WGHSMGGGICLNYACQGKHK 139 + + + + ++ A + + G+S+GG I + + Sbjct: 59 SDKPATGY---------SIMEHADDVVAVLDALKVDRAVFVGNSIGGMIAMQLNLDHPQR 109 Query: 140 NEISGYIGSGPLI--ILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRA 197 + + SG + + P I V + + I A Sbjct: 110 VIGNLILSSGTGLGEGMPPEAGAAFQNDYIGAFGGLLEGAVSARSKRERPEIL---AVMK 166 Query: 198 FLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPK 257 S P + P + D A K+ + IQ P +++ G++D + Sbjct: 167 AHFSVPSNFPKHVFDAATADPNGVFAWNIKDRLSSIQ------APTLVVAGEEDLVTTVA 220 Query: 258 GSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 301 ++ + P A EL++ H + LE FN + Sbjct: 221 NNQLLADNIPGA--ELRVINDVGH-FYQLERPSEFNELLRGFVA 261 >3KSR-A nrPDB Length = 290 Score = 43.3 bits (100), Expect = 1e-04, Method: Composition-based stats. Identities = 35/205 (17%), Positives = 57/205 (27%), Gaps = 14/205 (6%) Query: 34 NGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEY 93 T VL +HG+G G TFD RG + R + Sbjct: 24 TPTGMPG--VLFVHGWGGSQHHSLVRAREAVGLGCICMTFDLRGHEGYASMRQSVTRAQ- 80 Query: 94 HVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLII 153 +D++ ++ S + + G S GG + + + P + Sbjct: 81 -NLDDIKAAYDQLASLPYVDAHSIAVVGLSYGGYLSALLTRERP----VEWLALRSPALY 135 Query: 154 LHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFR 213 H K + P L + R G A A D + V Sbjct: 136 KDAHWDQPKVSLNADPDLMDYRRRALA------PGDNLALAACAQYKGDVLLVEAENDVI 189 Query: 214 QIHDFMQRGAKLYKNENNYIQKNFA 238 H M+ A + N + + A Sbjct: 190 VPHPVMRNYADAFTNARSLTSRVIA 214 >1UFO-A nrPDB Length = 238 Score = 42.9 bits (99), Expect = 2e-04, Method: Composition-based stats. Identities = 24/126 (19%), Positives = 43/126 (34%), Gaps = 12/126 (9%) Query: 36 TNEVRGRVLLIHGFGEYTKIQFRLMDHLSL---NGYESFTFDQRGAGVTSPGRSKGVTDE 92 + +L +HG + ++ L G+ FD G + Sbjct: 20 PEAPKALLLALHGL---QGSKEHILALLPGYAERGFLLLAFDAPRHGEREGPPPSSKSPR 76 Query: 93 Y--HVFNDLEHFVEKNLSECK----AKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYI 146 Y V+ F E+ + G+PLF+ G S+G + +G + +I Sbjct: 77 YVEEVYRVALGFKEEARRVAEEAERRFGLPLFLAGGSLGAFVAHLLLAEGFRPRGVLAFI 136 Query: 147 GSGPLI 152 GSG + Sbjct: 137 GSGFPM 142 >6AVW-A nrPDB Length = 230 Score = 41.4 bits (95), Expect = 5e-04, Method: Composition-based stats. Identities = 21/104 (20%), Positives = 36/104 (34%), Gaps = 11/104 (10%) Query: 205 SVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQ 264 SV LY + + + + K P++ HG DD + + + + Sbjct: 117 SVLLYPKTLGGGAVLSGWVPFTSSIISQFPEEAKKT-PILWSHGTDDRMVLFEAGQAALP 175 Query: 265 DCPSADK--ELKLYPGARHSIFSLETDKVFNTVFNDMKQWLDKH 306 A E K YPG HSI + E ++ W+ + Sbjct: 176 FLKEAGVTCEFKAYPGLGHSISNKE--------LKYIESWIKRR 211 >3C5W-P nrPDB Length = 310 Score = 41.0 bits (94), Expect = 8e-04, Method: Composition-based stats. Identities = 41/276 (14%), Positives = 80/276 (28%), Gaps = 30/276 (10%) Query: 29 FWPVQNGTNEVRGRVLLIHGFGEYTKIQF-RLMDHLSLNGYESFTFDQRGAGVTSPGRSK 87 F ++G+ +LL+HG G +S D R G T ++ Sbjct: 33 FRVYKSGSEGP--VLLLLHGGGHSALSWAVFTAAIISRVQCRIVALDLRSHGETKV-KNP 89 Query: 88 GVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIG 147 + D+ + VE + P+ + GH+MGG I ++ A Sbjct: 90 EDLSAETMAKDVGNVVEAMYGD---LPPPIMLIGHAMGGAIAVHTASSN----------L 136 Query: 148 SGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVP 207 L+ L + + FL I + V Sbjct: 137 VPSLLGLCMIDVVEGTAMDALNSMQNFLRGRPKTFKSLENAIEWSVKSGQIRNLESARVS 196 Query: 208 LYGSFRQIHDF-------MQRGAKLYKNENNYIQKNF-AKDKPVIIMHGQDDTINDPKGS 259 + G +Q + + K + + F + P +++ D + Sbjct: 197 MVGQVKQCEGKPYTWRIELAKTEKYWDGWFRGLSNLFLSCPIPKLLLLAGVDRL-----D 251 Query: 260 EKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTV 295 + ++++ P H++ DKV V Sbjct: 252 KDLTIGQMQGKFQMQVLPQCGHAVHEDAPDKVAEAV 287 >1R1D-A nrPDB Length = 247 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 47/264 (17%), Positives = 80/264 (30%), Gaps = 41/264 (15%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 VLL+HGF + L L GY +G GV + +D Sbjct: 19 VLLLHGFTGNSADVRMLGRFLESKGYTCHAPIYKGHGVPPEELV------HTGPDDWWQD 72 Query: 103 VEKNLSECKAKGIP-LFMWGHSMGGGICLNYACQGKHKNEISGYI-GSGPLIILHPHTMY 160 V K KG + + G S+GG L I G + P+ I TMY Sbjct: 73 VMNGYQFLKNKGYEKIAVAGLSLGGVFSLKLGYTVP----IEGIVTMCAPMYIKSEETMY 128 Query: 161 NKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQ 220 + + K+ F+Q M+ Sbjct: 129 EGVLEYAREYKKR-----------------EGKSEEQIEQE-------MERFKQTP--MK 162 Query: 221 RGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGAR 280 L + + P ++ + D + +P + + S K++K Y + Sbjct: 163 TLKALQELIADVRAHLDLVYAPTFVVQARHDEMINPDSANIIYNEIESPVKQIKWYEQSG 222 Query: 281 HSIFSLETDKVFNTVFNDMKQWLD 304 H I D+ + + D+ +L+ Sbjct: 223 HVI---TLDQEKDQLHEDIYAFLE 243 >3WMR-A nrPDB Length = 315 Score = 40.6 bits (93), Expect = 8e-04, Method: Composition-based stats. Identities = 54/300 (18%), Positives = 101/300 (33%), Gaps = 46/300 (15%) Query: 25 FGYMFW-PVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSP 83 Y W V + + V+L+HG T M L+ G+ +DQ G G ++ Sbjct: 30 GQYRTWYRVTGDLHSGKPPVVLLHGGPGSTHDYLLAMTSLTEAGWPVVHYDQLGNGGST- 88 Query: 84 GRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEIS 143 +++ E ++ L++ G + ++G S GG + +A + + Sbjct: 89 -HLPEKGEDFWTVQLFEDELDNLLNQLGIAGDYV-LFGQSWGGMLGSVHAARRP-----A 141 Query: 144 GYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAY-----RAF 198 G G L++ + Q +A L A P V+ T+D RAF Sbjct: 142 GLRG---LVVANAPASMKIWLQEMARLRALLPPDVQETLLKHEAARTTDTEEYFHAMRAF 198 Query: 199 LGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKD------------------ 240 + + DF ++Y + Y N + Sbjct: 199 YDRHVCRIVPW-----PRDFAATFMEIYNDPTVYTTMNGPNEFHVIGTLRDWSVEDCLPD 253 Query: 241 --KPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFND 298 P +++ G+ D + F+ P D ++ + H + LE + F+ V D Sbjct: 254 IQVPTMVLIGRHDEATPA-TVKPFLDLVP--DVRYEVLENSSH-VPHLEEPERFHEVMID 309 >6FKX-A nrPDB Length = 324 Score = 40.2 bits (92), Expect = 0.001, Method: Composition-based stats. Identities = 50/312 (16%), Positives = 89/312 (28%), Gaps = 61/312 (19%) Query: 1 MAPYPYKVQTTV-PELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRL 59 + P + L + G + E +L HG+ + Sbjct: 48 IEPAEFTTPLARCSHLWFTGTGGVRVHAKLLRP-VAPVEPHPALLQFHGYTGNSGDWSSR 106 Query: 60 MDHLSLNGYESFTFDQRGAGVTSPGRSK------------GVTDE-------YHVFNDLE 100 + ++ GY D RG S G + G+ D+ H+F D Sbjct: 107 LHYV-ALGYTVAALDCRGQAGLSVGEAPVENWSMASYLLRGIDDDAADNLALRHLFLDTA 165 Query: 101 HFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMY 160 + L+ + G+S GGG+ L A Sbjct: 166 RLAQIVLAMDDVDPDRVAATGYSQGGGLTLACAALEPR---------------------- 203 Query: 161 NKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQ 220 ++ AP+ FL R +DL+ ++ F DP R+ F + Sbjct: 204 ---IRLAAPVYP-FLCDFRRAWEMDLEKGPYNEITTYFRARDP------RHLREEEIFSR 253 Query: 221 RGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGAR 280 G ++ ++ + D I P ++ + K+ +LYP Sbjct: 254 LGYVDVQHLAPRVRAEVLMTVSL------ADKICPP-STQFAAYNKLGGPKDYRLYPDFA 306 Query: 281 HSIFSLETDKVF 292 H D +F Sbjct: 307 HETLPGTDDAIF 318 >4EB0-A nrPDB Length = 258 Score = 39.8 bits (91), Expect = 0.001, Method: Composition-based stats. Identities = 43/243 (17%), Positives = 73/243 (30%), Gaps = 22/243 (9%) Query: 5 PYKVQT-TVPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHL 63 P+ V T TV L F G Y GT+ G + + G+ L L Sbjct: 20 PFSVATYTVSRLSVSGFGGGVIYY-----PTGTSLTFGGIAMSPGYTADASSLAWLGRRL 74 Query: 64 SLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHS 123 + +G+ + R+ ++ + + + L + GHS Sbjct: 75 ASHGFVVLVINTNSRFDYPDSRASQLSAALNYLRTSSPSAVRARLDANR----LAVAGHS 130 Query: 124 MGGGICLNYACQGKHKNEISGYI---------GSGPLIILHPHTMYNKPTQIIAPLLAKF 174 MGGG L A Q S P++I+ P A + Sbjct: 131 MGGGGTLRIAEQNPSLKAAVPLTPWHTDKTFNTSVPVLIVGAEADTVAPVSQHAIPFYQN 190 Query: 175 LPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQ 234 LP ++L + + + +SV + D R + N N+ Sbjct: 191 LPSTTPKVYVELDNAS---HFAPNSNNAAISVYTISWMKLWVDNDTRYRQFLCNVNDPAL 247 Query: 235 KNF 237 +F Sbjct: 248 SDF 250 >5YHP-A nrPDB Length = 355 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 45/291 (15%), Positives = 90/291 (30%), Gaps = 45/291 (15%) Query: 32 VQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTD 91 N + V+ +HG G + Y FDQRG+G ++P Sbjct: 65 YGNPQGKP---VVFLHG-GPGGGASDSDARRFNPTTYRIVLFDQRGSGESTPASCLEDNT 120 Query: 92 EYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPL 151 + D+E + + G ++G S G + L YA H + G Sbjct: 121 TQALVEDIEKI--REFLQV---GAAWHVFGGSWGSTLALAYA--QAHPARVKSLTLRGIF 173 Query: 152 IILHPH----TMYNKPTQIIAPLLAKFLPRVRIDTGLDL------KGITSDKAYRAFLGS 201 + + + ++L + + D+ + SD+ RA G Sbjct: 174 TLRKKELDFFYQGPGSSFVFPEYWEEYLDPIPVAERGDMVKAYYERLTGSDEKVRAEAGR 233 Query: 202 DPMSVPLYGSFRQIHD--FMQRGAKLYKNENNYIQKNFAKD------------------- 240 + S + + A + + I+ ++ + Sbjct: 234 AWSRWEMATSRLHVDPDYISKADAPGFADAFARIESHYFVNGGFMPEGELLKPENIAKIS 293 Query: 241 -KPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDK 290 P +I+ G+ D + + + + P + + + P A HS T+K Sbjct: 294 HIPAVIVQGRYDMVCPITTAYELTKLWP--EAKFVVIPDAGHSAIEAGTEK 342 >2RON-A nrPDB Length = 242 Score = 39.5 bits (90), Expect = 0.002, Method: Composition-based stats. Identities = 40/217 (18%), Positives = 72/217 (33%), Gaps = 37/217 (17%) Query: 90 TDEYHVFNDLEHFVEKNLSECK-AKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGS 148 T++ DLE + E P ++GHSMGG I A + + + + Sbjct: 52 TNQTSAIEDLEELTDLYKQELNLRPDRPFVLFGHSMGGMITFRLAQKLEREGIFPQAVII 111 Query: 149 GPLIILHPHTMYNKPTQIIAPLLAKFLPRVRI-DTGLDLKGITSDKAYRAFLGSDPMSVP 207 + P + K LP + D + L G+ ++ + S Sbjct: 112 S---AIQPPHIQRKKVS--------HLPDDQFLDHIIQLGGMPAELVENKEVMS------ 154 Query: 208 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFA-KDKPVIIMHGQDDTIN--DPKGSEKFIQ 264 F+ Y+ + + A PV + +G DD D +G +K+ Sbjct: 155 ---------FFLPSFRSDYRALEQFELYDLAQIQSPVHVFNGLDDKKCIRDAEGWKKWA- 204 Query: 265 DCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 301 D + G H +T++V +F + Q Sbjct: 205 ----KDITFHQFDGG-HMFLLSQTEEVAERIFAILNQ 236 >2YYS-A nrPDB Length = 286 Score = 38.7 bits (88), Expect = 0.003, Method: Composition-based stats. Identities = 53/283 (18%), Positives = 94/283 (33%), Gaps = 37/283 (13%) Query: 33 QNGTNEVRGRVLLIHGFGEYTKI-QFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTD 91 G E +L G G + + L D+L G+ FDQRG+G RS + Sbjct: 19 DVGPVEGPALFVLHGGPGGNAYVLREGLQDYL--EGFRVVYFDQRGSG-----RSLELPQ 71 Query: 92 EYHVFNDLEHFVEKNLSECKAKGIPLF-MWGHSMGGGICLNYACQGKHKNEISGYIGSGP 150 + +F ++ VE L +A G+ F + H G + L + G I P Sbjct: 72 DPRLF-TVDALVEDTLLLAEALGVERFGLLAHGFGAVVALEVLRRFPQA---EGAILLAP 127 Query: 151 LIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLG----SDPMSV 206 + N P + A L D +LK + +A P Sbjct: 128 WV--------NFP-WLAARLAEAAGLAPLPDPEENLKEALKREEPKALFDRLMFPTPRGR 178 Query: 207 PLYGSFRQIHDFMQRGAKLY------KNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSE 260 Y + + A +Y + +P+ ++ G+ D + P E Sbjct: 179 MAYEWLAEGAGILGSDAPGLAFLRNGLWRLDYTPYLTPERRPLYVLVGERDGTSYPYAEE 238 Query: 261 KFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQWL 303 + +++ P A H ++ ++ + F F + L Sbjct: 239 VASRLR----APIRVLPEAGHYLW-IDAPEAFEEAFKEALAAL 276 >3FCY-A nrPDB Length = 346 Score = 38.7 bits (88), Expect = 0.004, Method: Composition-based stats. Identities = 23/138 (16%), Positives = 44/138 (31%), Gaps = 20/138 (14%) Query: 20 FDGAKFGYMFWPVQNGTNEVRGRVLLI-HGFGEYTKIQFRLMDHLSLNGYESFTFDQRGA 78 F G + + E + L+ HG+ + ++++ G+ D RG Sbjct: 87 FTGVRGARIHAKYIKPKTEGKHPALIRFHGYSSNSGDWNDKLNYV-AAGFTVVAMDVRGQ 145 Query: 79 GVTS---PGRSKGVTDEY---------------HVFNDLEHFVEKNLSECKAKGIPLFMW 120 G S G + + + H+F D ++ + + + Sbjct: 146 GGQSQDVGGVTGNTLNGHIIRGLDDDADNMLFRHIFLDTAQLAGIVMNMPEVDEDRVGVM 205 Query: 121 GHSMGGGICLNYACQGKH 138 G S GGG+ L A Sbjct: 206 GPSQGGGLSLACAALEPR 223 >1R3D-A nrPDB Length = 264 Score = 38.3 bits (87), Expect = 0.004, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 41/101 (40%), Gaps = 7/101 (6%) Query: 36 TNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHV 95 V+L+HG ++ HL+ + T D G G T+P R Sbjct: 12 PTARTPLVVLVHGLLGSGADWQPVLSHLARTQCAALTLDLPGHG-TNPERHC------DN 64 Query: 96 FNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQG 136 F + +E+ + +P+ + G+S+GG + ++ QG Sbjct: 65 FAEAVEMIEQTVQAHVTSEVPVILVGYSLGGRLIMHGLAQG 105 >4GDM-A nrPDB Length = 268 Score = 37.1 bits (84), Expect = 0.009, Method: Composition-based stats. Identities = 20/94 (21%), Positives = 38/94 (40%), Gaps = 11/94 (11%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 ++ +HGF + + + Y D G G ++ G F+D+ Sbjct: 33 LVFLHGFSGDCHEWQEVGE--AFADYSRLYVDLPGHGGSAAISVDG-------FDDVTDL 83 Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQG 136 + K L + ++ G+S+GG + + ACQG Sbjct: 84 LRKTL--VSYNILDFWLVGYSLGGRVAMMAACQG 115 >3V48-A nrPDB Length = 268 Score = 36.8 bits (83), Expect = 0.013, Method: Composition-based stats. Identities = 43/266 (16%), Positives = 86/266 (32%), Gaps = 21/266 (7%) Query: 26 GYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGR 85 G+M + V+LI G G + L Y+ +DQRG G Sbjct: 1 GHMKLSLSPPPYADAPVVVLISGLGGSGSYWLPQLAVLE-QEYQVVCYDQRGTGNNPDT- 58 Query: 86 SKGVTDEYHVFNDLEHFVEKNLSECKAKGI-PLFMWGHSMGGGICLNYACQGKHKNEISG 144 + ++Y + + A GI + GH++G + + A + ++ Sbjct: 59 ---LAEDYS----IAQMAAELHQALVAAGIEHYAVVGHALGALVGMQLALD--YPASVTV 109 Query: 145 YIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPM 204 I + ++ HT + + + L ++ + + A + + Sbjct: 110 LISVNGWLRINAHT------RRCFQVRERLLYSGGAQAWVEAQPLFLYPADWMAARAPRL 163 Query: 205 SV--PLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKF 262 L + Q + + R K ++ PV I+ DD + S + Sbjct: 164 EAEDALALAHFQGKNNLLRRLNALKRA-DFSHHADRIRCPVQIICASDDLLVPTACSSEL 222 Query: 263 IQDCPSADKELKLYPGARHSIFSLET 288 P + K + Y G ++ ET Sbjct: 223 HAALPDSQKMVMPYGGHACNVTDPET 248 >4G5X-A nrPDB Length = 279 Score = 35.6 bits (80), Expect = 0.028, Method: Composition-based stats. Identities = 19/124 (15%), Positives = 38/124 (30%), Gaps = 10/124 (8%) Query: 41 GRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLE 100 +L+IHG I ++ + D G G ++ +E Sbjct: 25 APLLMIHGNSSSGAIFAPQLEGEIGKKWRVIAPDLPGHGKSTDAIDP------DRSYSME 78 Query: 101 HFVEKNLSECKAKGIPLFMW-GHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTM 159 + + + GI + G S+GG I + + E+ G + +G + Sbjct: 79 GYADAMTEVMQQLGIADAVVFGWSLGGHIGIEMIARYP---EMRGLMITGTPPVAREEVG 135 Query: 160 YNKP 163 Sbjct: 136 QGFK 139 >1Q0R-A nrPDB Length = 298 Score = 34.8 bits (78), Expect = 0.054, Method: Composition-based stats. Identities = 41/276 (14%), Positives = 74/276 (26%), Gaps = 27/276 (9%) Query: 29 FWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKG 88 W G +L++ G L+ G +D R G ++ Sbjct: 13 LWSDDFGDPADPALLLVMGGNLSALGWPDEFARRLADGGLHVIRYDHRDTGRST------ 66 Query: 89 VTDEYHVFNDLEHFVEKNLSECKAKGIPLF-MWGHSMGGGICLNYACQGKHKNEISGYIG 147 D ++ G+ + G SMG I A + + Sbjct: 67 TRDFAAHPYGFGELAADAVAVLDGWGVDRAHVVGLSMGATITQVIALDHHDRLSSLTMLL 126 Query: 148 SGPLII---------LHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAF 198 G L I + + P L + G + +R Sbjct: 127 GGGLDIDFDANIERVMRGEPTLDGLPGPQQPFLDALALMNQPAEGRAAEVAKRVSKWRIL 186 Query: 199 LGSD-PMSVPLYGSF--RQIHDFMQRGAKLYKNEN------NYIQKNFAKDKPVIIMHGQ 249 G+ P Y + R I A+ Y + + + + P +++ + Sbjct: 187 SGTGVPFDDAEYARWEERAIDHAGGVLAEPYAHYSLTLPPPSRAAELREVTVPTLVIQAE 246 Query: 250 DDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFS 285 D I + P+A L PG H++ S Sbjct: 247 HDPIAPAPHGKHLAGLIPTA--RLAEIPGMGHALPS 280 >2ECF-A nrPDB Length = 741 Score = 34.1 bits (76), Expect = 0.073, Method: Composition-based stats. Identities = 12/44 (27%), Positives = 20/44 (45%), Gaps = 2/44 (4%) Query: 242 PVIIMHGQDDTINDPKGSEKFIQDCPSADK--ELKLYPGARHSI 283 P++++HG D S + + EL YPGA+H + Sbjct: 676 PLLLIHGMADDNVLFTNSTSLMSALQKRGQPFELMTYPGAKHGL 719 >5UGZ-A nrPDB Length = 260 Score = 33.7 bits (75), Expect = 0.10, Method: Composition-based stats. Identities = 40/222 (18%), Positives = 66/222 (29%), Gaps = 34/222 (15%) Query: 78 AGVTSPGRSKGVTDEYHVFNDL-EHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQG 136 AG + R DL + FV+ G ++GHS+GG + Sbjct: 58 AGRGTRIRQPLCLTMVDAVADLYQQFVKH------YTGGDYAIFGHSLGGIMAF------ 105 Query: 137 KHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYR 196 E+ YI H H M A + P R + L + Sbjct: 106 ----ELVHYILD------HGHDMP------CALFFSGCRPPDRASHEVILHTLPDQAFME 149 Query: 197 AF--LGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTIN 254 LG P+ V I + + + + K P+++ HG D + Sbjct: 150 EIVKLGGTPVDVFRNKELMTIFTPIIKNDYRLYEQYVFQAKARTLTCPIVLFHGDADNLV 209 Query: 255 DPKGSEKFIQDCPSADKE-LKLYPGARHSIFSLETDKVFNTV 295 E + + K ++P A H ++V V Sbjct: 210 --MQDELLAWEKFTTRKTRTIIFPAADHFFVDKHFEQVVGYV 249 >5YP1-A nrPDB Length = 745 Score = 33.3 bits (74), Expect = 0.14, Method: Composition-based stats. Identities = 14/69 (20%), Positives = 27/69 (39%), Gaps = 2/69 (2%) Query: 217 DFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADK--ELK 274 D + Y+ + + + ++++HG D S K + + EL Sbjct: 655 DLPKANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELM 714 Query: 275 LYPGARHSI 283 YPGA+H + Sbjct: 715 TYPGAKHGL 723 >3CN7-A nrPDB Length = 226 Score = 33.3 bits (74), Expect = 0.15, Method: Composition-based stats. Identities = 26/125 (20%), Positives = 44/125 (35%), Gaps = 15/125 (12%) Query: 187 KGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKD-----K 241 KGI +++ A S +V L+ +FR+ + L + + A D Sbjct: 111 KGIAAERIILAGF-SQGGAVVLHTAFRRYAQPLGGVLALSTYAPTF--DDLALDERHKRI 167 Query: 242 PVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDMKQ 301 PV+ +HG D + DP + E+ H +V +D+ Sbjct: 168 PVLHLHGSQDDVVDPALGRAAHDALQAQGVEV-----GWHDYPMGH--EVSLEEIHDIGA 220 Query: 302 WLDKH 306 WL K Sbjct: 221 WLRKR 225 >5DWD-A nrPDB Length = 240 Score = 32.9 bits (73), Expect = 0.17, Method: Composition-based stats. Identities = 26/130 (20%), Positives = 45/130 (34%), Gaps = 7/130 (5%) Query: 165 QIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAK 224 + P+L FL + TGL +D F M++ + + + Sbjct: 109 ETAHPVLDAFLADLWAQTGL----GPADTILVGFSQGAMMALYTGLRLPEPLKAIIAFSG 164 Query: 225 LYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSA--DKELKLYPGARHS 282 L ++ A PV+++HG D + GSE + D L + G+ H+ Sbjct: 165 LIV-APEKLEAEIASKPPVLLIHGDLDDVVPVIGSETALPKLIDLGIDARLHISQGSGHT 223 Query: 283 IFSLETDKVF 292 I D Sbjct: 224 IAQDGLDTAT 233 >1Y7H-A nrPDB Length = 268 Score = 32.9 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 42/259 (16%), Positives = 85/259 (32%), Gaps = 17/259 (6%) Query: 44 LLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHFV 103 +L+HG ++L L G++ D +G T + + + Y L + Sbjct: 8 VLVHGACHGGWSWYKLKPLLEAAGHKVTALDLAASG-TDLRKIEELRTLYDYTLPLMELM 66 Query: 104 EKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHT----M 159 E ++ K + + GHS+GG + K + ++ + +H + Sbjct: 67 ESLSADEK-----VILVGHSLGGMNLGLAMEKYPQKIYAAVFLAAFMPDSVHNSSFVLEQ 121 Query: 160 YNKPTQIIAPLLAKFLP-RVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDF 218 YN+ T L +FLP + + A++ + P + L S + Sbjct: 122 YNERTPAENWLDTQFLPYGSPEEPLTSMFFGPKFLAHKLYQLCSPEDLALASSLVRPSSL 181 Query: 219 MQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPG 278 + + + F K V I+ +D + I + + G Sbjct: 182 ---FMEDLSKAKYFTDERFGSVKRVYIV-CTEDKGIPEEFQRWQIDNIGVTEA--IEIKG 235 Query: 279 ARHSIFSLETDKVFNTVFN 297 A H E K+ ++ Sbjct: 236 ADHMAMLCEPQKLCASLLE 254 >3V1K-A nrPDB Length = 286 Score = 32.9 bits (73), Expect = 0.18, Method: Composition-based stats. Identities = 40/241 (16%), Positives = 70/241 (29%), Gaps = 47/241 (19%) Query: 43 VLLIHGFGEYTKIQFRLMDHLS---LNGYESFTFDQRGAGVTSP---GRSKGVTDEYHVF 96 V+++HG G ++ GY D G + +G+ + V Sbjct: 36 VIMLHGGGPGAGGWSNYYRNVGPFVDAGYRVILKDSPGFNKSDAVVMDEQRGLVNARAVK 95 Query: 97 NDLEHF-VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILH 155 ++ +++ + G+SMGG LN+A + I I GP Sbjct: 96 GLMDALDIDRAH-----------LVGNSMGGATALNFALEYPD--RIGKLILMGPG---- 138 Query: 156 PHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFL------GSDPMSVPLY 209 + AP +P I L S + + L S L Sbjct: 139 -----GLGPSMFAP-----MPMEGIKLLFKLYAEPSYETLKQMLQVFLYDQSLITEELLQ 188 Query: 210 GSFRQIH-------DFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKF 262 G + I +F+ K + + + I G+DD K Sbjct: 189 GRWEAIQRQPEHLKNFLISAQKAPLSTWDVTARLGEIKAKTFITWGRDDRFVPLDHGLKL 248 Query: 263 I 263 + Sbjct: 249 L 249 >3BF8-A nrPDB Length = 255 Score = 32.9 bits (73), Expect = 0.19, Method: Composition-based stats. Identities = 42/264 (15%), Positives = 86/264 (32%), Gaps = 27/264 (10%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYHVFNDLEHF 102 ++L+HG L L +N + D R G++ + V + + DL Sbjct: 19 IVLVHGLFGSLDNLGVLARDL-VNDHNIIQVDVRNHGLSP---REPVMNYPAMAQDLVDT 74 Query: 103 VEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNK 162 ++ + GHSMGG + + + I P+ + Sbjct: 75 LDAQQIDK------ATFIGHSMGGKAVMALTALAPDRIDKLVAIDIAPV-----DYHVRR 123 Query: 163 PTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRG 222 +I A + A + T I + + + G +R + Sbjct: 124 HDEIFAAINA--VSESDAQTRQQAAAIMRQHLNEEGVIQFLLKSFVDGEWRFN---VPVL 178 Query: 223 AKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHS 282 Y + + +K A D P + + G + + + + P A + GA H Sbjct: 179 WDQYPHIVGW-EKIPAWDHPALFIPGGNSPYVSEQYRDDLLAQFPQARAHVIA--GAGHW 235 Query: 283 IFSLETDKVFNTVFNDMKQWLDKH 306 + + + D V ++++L+ H Sbjct: 236 VHAEKPD----AVLRAIRRYLNDH 255 >4XJV-A nrPDB Length = 271 Score = 32.5 bits (72), Expect = 0.21, Method: Composition-based stats. Identities = 37/217 (17%), Positives = 72/217 (33%), Gaps = 27/217 (12%) Query: 78 AGVTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKA--KGIPLFMWGHSMGGGICLNYACQ 135 + PGR V E + ND+ V++ + + + P +GHSMG I A Sbjct: 62 HSLRLPGRESRV--EEPLENDISQLVDEVVCALQPVIQDKPFAFFGHSMGSYIAFRTALG 119 Query: 136 GKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAY 195 K N+ P ++ P+ +K R+ D L + I+ Sbjct: 120 LKENNQ--------------PEPLHLF-LSSATPVHSKAWHRIPKDDELSEEQISHYLME 164 Query: 196 RAFLGSDPMSVPLYGSF-RQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTIN 254 G P F +Q ++ + ++ + + + G +D Sbjct: 165 ---FGGTPKHFAEAKEFVKQCSPIIRADLNIVRSCTSNVPSKAVLSCDLTCFVGSEDIAK 221 Query: 255 DPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKV 291 D + +D S + ++ PG + +K+ Sbjct: 222 DMEA----WKDVTSGNAKIYQLPGGHFYLLDPANEKL 254 >5LZ5-A nrPDB Length = 388 Score = 32.1 bits (71), Expect = 0.31, Method: Composition-based stats. Identities = 9/47 (19%), Positives = 17/47 (36%) Query: 30 WPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQR 76 W E V+ HG G + + + L+ +G+ + R Sbjct: 89 WNSPLRPGEKYPLVVFSHGLGAFRTLYSAIGIDLASHGFIVAAVEHR 135 >4CCW-A nrPDB Length = 299 Score = 31.8 bits (70), Expect = 0.38, Method: Composition-based stats. Identities = 46/273 (16%), Positives = 92/273 (33%), Gaps = 48/273 (17%) Query: 34 NGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRG-AGVTSPGRSKGVTDE 92 +G + VLL HG + + + + S Y ++ D G + P G + Sbjct: 49 SGPEDAPPLVLL-HGALFSSTMWYPNIADWSSK-YRTYAVDIIGDKNKSIPENLSGTRTD 106 Query: 93 Y-----HVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIG 147 Y VF++L +EK+ M G S+GG +N+ + + + + + Sbjct: 107 YANWLLDVFDNLG--IEKSH-----------MIGLSLGGLHTMNFLLRMPERVKSAAILS 153 Query: 148 SGPLIILHPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVP 207 + H Y + A ++ L+ + + P Sbjct: 154 PAETFLPFHHDFYKYALGLTA--------SNGVEKFLNW-----------MMTDQNVLHP 194 Query: 208 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKD------KPVIIMHGQDDTINDPKGSEK 261 ++ Q Q G++ + + F + P++++ G+ + I DP S Sbjct: 195 IFVKQFQAGVMWQDGSRNPNPKADGFPYVFTDEELRSARVPILLLLGEHEVIYDPH-SAL 253 Query: 262 FIQDCPSADKELKLYPGARHSIFSLETDKVFNT 294 D E ++ A H + S+E N Sbjct: 254 HRASSFVPDIEAEVIKNAGH-VLSMEQPAYVNE 285 >1Z68-A nrPDB Length = 719 Score = 31.4 bits (69), Expect = 0.49, Method: Composition-based stats. Identities = 14/78 (17%), Positives = 34/78 (43%), Gaps = 2/78 (2%) Query: 226 YKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKL--YPGARHSI 283 YKN + + ++ +++HG D + S + + +A + + Y H + Sbjct: 639 YKNSTVMARAEYFRNVDYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL 698 Query: 284 FSLETDKVFNTVFNDMKQ 301 L T+ ++ + + +KQ Sbjct: 699 SGLSTNHLYTHMTHFLKQ 716 >2EDA-A nrPDB Length = 310 Score = 31.4 bits (69), Expect = 0.58, Method: Composition-based stats. Identities = 10/67 (14%), Positives = 25/67 (37%), Gaps = 4/67 (5%) Query: 16 QYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQ 75 + G + Y+ G ++ L +HG ++ + +++ + +G D Sbjct: 27 DLPGYPGLRAHYL----DEGNSDAEDVFLCLHGEPTWSYLYRKMIPVFAESGARVIAPDF 82 Query: 76 RGAGVTS 82 G G + Sbjct: 83 FGFGKSD 89 >3EMV-A nrPDB Length = 253 Score = 31.4 bits (69), Expect = 0.59, Method: Composition-based stats. Identities = 32/175 (18%), Positives = 55/175 (31%), Gaps = 8/175 (4%) Query: 80 VTSPGRSKGVTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHK 139 V PGR V + DL + E EC KG H +G C + + Sbjct: 23 VGDPGRVDKVKVLCDSYVDLAYNREYKSVECTYKGQKFLCVSHGVGSAGCAICFEELMNN 82 Query: 140 NEISGYIGSGPLIILHPHTMYNKPTQII-APLLAKFLPRVRIDTGLDLKGITSDKAYRAF 198 I +G L P M I A + + + I D + + Y Sbjct: 83 GAK-VIIRAGSCGSLQPTQMKRGDICICNAAVREDRVSHLMI--YSDFPAVADYEVYATL 139 Query: 199 LG-SDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQKNFA---KDKPVIIMHGQ 249 ++ + VP++ D + +Y + N A + +++ G Sbjct: 140 NQVAEELKVPVFNGISLSSDMYYPHKIIPTRLEDYSKANVAVVEMEVATLMVMGT 194 >3O0D-A nrPDB Length = 301 Score = 31.0 bits (68), Expect = 0.74, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 17/46 (36%) Query: 111 KAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHP 156 + + + GHS+GG L + K + G I+ + Sbjct: 150 QYPDYQIAVTGHSLGGAAALLFGINLKVNGHDPLVVTLGQPIVGNA 195 >1THT-A nrPDB Length = 305 Score = 31.0 bits (68), Expect = 0.77, Method: Composition-based stats. Identities = 15/52 (28%), Positives = 22/52 (42%), Gaps = 4/52 (7%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYH 94 +L+ GF L ++LS NG+ F +D G S G DE+ Sbjct: 38 ILIASGFARRMDHFAGLAEYLSTNGFHVFRYDSLHH----VGLSSGSIDEFT 85 >3AZQ-A nrPDB Length = 662 Score = 30.6 bits (67), Expect = 0.80, Method: Composition-based stats. Identities = 9/49 (18%), Positives = 21/49 (42%), Gaps = 8/49 (16%) Query: 241 KPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETD 289 P +++ G +D + P+ ++F++ G H+ S E + Sbjct: 583 VPFLLLQGLEDPVCPPEQCDRFLEAVAGC--------GVPHAYLSFEGE 623 >5YAL-A nrPDB Length = 342 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 26/147 (17%), Positives = 42/147 (28%), Gaps = 18/147 (12%) Query: 34 NGTNEVRGRVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTS--PGRSKG--- 88 R V+L GFG L + L+ GY D GR + Sbjct: 86 RPAPVPRPLVVLSPGFGMSRITLTALGEDLASRGYAVAAVDHTYEAPVEFPGGRIEKCTL 145 Query: 89 -----------VTDEYHVFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGK 137 V + + + SE + + + GHS+GG + + + Sbjct: 146 CDDSRMDPGAVVRNRAKDLRFVLDRLTGPGSELRVDARRIGVAGHSIGGASAVEVMREDR 205 Query: 138 HKNEISGYIGSGPLIILHPHTMYNKPT 164 + + G P NKP Sbjct: 206 RVD--AAINLDGNFFTEPPAEGLNKPV 230 >2PPL-A nrPDB Length = 485 Score = 30.2 bits (66), Expect = 1.1, Method: Composition-based stats. Identities = 19/125 (15%), Positives = 38/125 (30%), Gaps = 10/125 (8%) Query: 99 LEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHT 158 + ++ L+E + + GHS+G + + + I+G P Sbjct: 155 VAQMLDILLTEYSYPPSKVHLIGHSLGAHVAGEAGSKTPGLSRITGLDPVEASFESTPEE 214 Query: 159 MYNKP-----TQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFR 213 + P +I A +P + T + + G + M + Sbjct: 215 VRLDPSDADFVDVIHTDAAPLIPFLGFGTNQQMGHLDFFPN-----GGESMPGCKKNALS 269 Query: 214 QIHDF 218 QI D Sbjct: 270 QIVDL 274 >6FVJ-A nrPDB Length = 261 Score = 30.2 bits (66), Expect = 1.3, Method: Composition-based stats. Identities = 30/190 (15%), Positives = 60/190 (31%), Gaps = 26/190 (13%) Query: 116 PLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPHTMYNKPTQIIAPLLAKFL 175 P+ +GHSMGG + A + + ++ + + P I L Sbjct: 97 PVAFFGHSMGGMLAFEVALRYQSAGHR---------VLAFFVSACSAPGHIRYKQLQDLS 147 Query: 176 PRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHDFMQRGAKLYKNENNYIQK 235 R +D + G+ D F D V + R + Sbjct: 148 DREMLDLFTRMTGMNPD-----FFTDDEFFVGALPTLRAVRAIAGYSC----------PP 192 Query: 236 NFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYPGARHSIFSLETDKVFNTV 295 P+ G D I + +D + + ++++PG H + ++ + + Sbjct: 193 ETKLSCPIYAFIGDKDWIA-TQDDMDPWRDRTTEEFSIRVFPG-DHFYLNDNLPELVSDI 250 Query: 296 FNDMKQWLDK 305 + QW D+ Sbjct: 251 EDKTLQWHDR 260 >3D2A-A nrPDB Length = 181 Score = 29.8 bits (65), Expect = 1.4, Method: Composition-based stats. Identities = 25/110 (22%), Positives = 42/110 (38%), Gaps = 15/110 (13%) Query: 43 VLLIHGFGEYTKIQFRLMDHLSLNGY---ESFTFDQRGAGVTSPGRSKGVTDEYHVFNDL 99 V+++HG G + + +L G+ + + D Y+ L Sbjct: 6 VVMVHGIGGASFNFAGIKSYLVSQGWSRDKLYAVD----------FWDKTGTNYNNGPVL 55 Query: 100 EHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSG 149 FV+K L E AK + + HSMGG L Y N+++ + G Sbjct: 56 SRFVQKVLDETGAKKVD--IVAHSMGGANTLYYIKNLDGGNKVANVVTLG 103 >3WYD-A nrPDB Length = 228 Score = 29.4 bits (64), Expect = 2.0, Method: Composition-based stats. Identities = 26/137 (18%), Positives = 39/137 (28%), Gaps = 17/137 (12%) Query: 42 RVLLIHGFGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSP-GRSKGVTDEYHVFNDLE 100 V+ +HG G F G + RG V P GR D+ Sbjct: 39 LVIALHGMGGDENSYFDSYQ----RGAFMIEAENRGYIVACPKGRQPASMYVGPAERDVM 94 Query: 101 HFVEKNLSECKAKGIPLFMWGHSMGG----------GICLNYACQGKHKNEISGY--IGS 148 + + + K ++M GHSMGG G I Sbjct: 95 DVIAEVRRDYKIDPDRIYMTGHSMGGYGTWSIAMNHPDVFAALAPVAGGGNPLGMANIAH 154 Query: 149 GPLIILHPHTMYNKPTQ 165 P +++H P + Sbjct: 155 IPQLVVHGDNDKTVPVE 171 >2C4K-A nrPDB Length = 370 Score = 28.7 bits (62), Expect = 3.6, Method: Composition-based stats. Identities = 27/214 (12%), Positives = 54/214 (25%), Gaps = 36/214 (16%) Query: 99 LEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIILHPH- 157 L H + +L + + +G F + L Y + + + P Sbjct: 146 LTHIITMDLHQKEIQGFFSFPVDNLRASPFLLQYIQEEIPNYRNAVIVAKSPDAAKRAQS 205 Query: 158 TMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQIHD 217 + + +D G + + L M + D Sbjct: 206 YAERLRLGLAVIHGEAQCTELDMDDGRHSPPMVKNATVHPGLELPLMMAKEKPPITVVGD 265 Query: 218 FMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKLYP 277 R A + + + ++ A + K+Y Sbjct: 266 VGGRIAIIVDDIIDDVESFVA------------------------AAEILKERGAYKIYV 301 Query: 278 GARHSIFSLETDK-----------VFNTVFNDMK 300 A H I S E + V NTV ++++ Sbjct: 302 MATHGILSAEAPRLIEESSVDEVVVTNTVPHEVQ 335 >1JFR-A nrPDB Length = 262 Score = 28.3 bits (61), Expect = 4.7, Method: Composition-based stats. Identities = 14/71 (19%), Positives = 26/71 (36%), Gaps = 2/71 (2%) Query: 242 PVIIMHGQDDTINDPKGSEK--FIQDCPSADKELKLYPGARHSIFSLETDKVFNTVFNDM 299 P +++ DT+ K + S DK GA H + + + + Sbjct: 168 PTLVVGADGDTVAPVATHSKPFYESLPGSLDKAYLELRGASHFTPNTSDTTIAKYSISWL 227 Query: 300 KQWLDKHTTTE 310 K+++D T E Sbjct: 228 KRFIDSDTRYE 238 Score = 27.9 bits (60), Expect = 5.5, Method: Composition-based stats. Identities = 20/71 (28%), Positives = 27/71 (38%), Gaps = 5/71 (7%) Query: 5 PYKVQTT-VPELQYENFDGAKFGYMFWPVQNGTNEVRGRVLLIHGFGEYTKIQFRLMDHL 63 PY T V L F G G +++P G V++ GF Y L L Sbjct: 22 PYATSQTSVSSLVASGFGG---GTIYYPTSTADGTF-GAVVISPGFTAYQSSIAWLGPRL 77 Query: 64 SLNGYESFTFD 74 + G+ FT D Sbjct: 78 ASQGFVVFTID 88 >2OCI-A nrPDB Length = 254 Score = 28.3 bits (61), Expect = 4.9, Method: Composition-based stats. Identities = 50/267 (18%), Positives = 83/267 (31%), Gaps = 32/267 (11%) Query: 36 TNEVRGRVLLIHG-FGEYTKIQFRLMDHLSLNGYESFTFDQRGAGVTSPGRSKGVTDEYH 94 T E VLL+ G G + +L+ + +D RG G + P D + Sbjct: 19 TGEGDHAVLLLPGMLGSGETDFGPQLKNLNKKLFTVVAWDPRGYGHSRPPDRDFPADFFE 78 Query: 95 VFNDLEHFVEKNLSECKAKGIPLFMWGHSMGGGICLNYACQGKHKNEISGYIGSGPLIIL 154 D + V+ + K + + G S GG L A + G+ + Sbjct: 79 --RDAKDAVDLMKALKFKK---VSLLGWSDGGITALIAAAKYPSYIHKMVIWGANAYVTD 133 Query: 155 HPHTMYNKPTQIIAPLLAKFLPRVRIDTGLDLKGITSDKAYRAFLGSDPMSVPLYGSFRQ 214 +Y ++K+ R R K A G D + Sbjct: 134 EDSMIYEGI-----RDVSKWSERTR-------------KPLEALYGYDYFARTCEKWVDG 175 Query: 215 IHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELK 274 I F K + N P +I+HG+ D + ++ L Sbjct: 176 IRQF-----KHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFI--HKHVKGSRLH 228 Query: 275 LYPGARHSIFSLETDKVFNTVFNDMKQ 301 L P +H++ D+ FN + D Q Sbjct: 229 LMPEGKHNLHLRFADE-FNKLAEDFLQ 254 >6IGR-A nrPDB Length = 656 Score = 27.5 bits (59), Expect = 7.7, Method: Composition-based stats. Identities = 16/91 (17%), Positives = 33/91 (36%), Gaps = 2/91 (2%) Query: 217 DFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIQDCPSADKELKL- 275 DF +R L + + +Q P +I+H D + +E++ ++ Sbjct: 564 DFSRRADALKLWDLSPLQYVENVKTPTLIVHSVLDHRCPVEQAEQWYAALHKHQVPVRFV 623 Query: 276 -YPGARHSIFSLETDKVFNTVFNDMKQWLDK 305 +P H + T N+ WL++ Sbjct: 624 RFPEENHELSRSGRPDRRLTRLNEYFAWLER 654 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.118 0.289 Lambda K H 0.267 0.0359 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 10,513,185 Number of Sequences: 36641 Number of extensions: 402279 Number of successful extensions: 1262 Number of sequences better than 10.0: 84 Number of HSP's better than 10.0 without gapping: 38 Number of HSP's successfully gapped in prelim test: 74 Number of HSP's that attempted gapping in prelim test: 1145 Number of HSP's gapped (non-prelim): 124 length of query: 313 length of database: 10,336,785 effective HSP length: 97 effective length of query: 216 effective length of database: 6,782,608 effective search space: 1465043328 effective search space used: 1465043328 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 58 (27.1 bits)