BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P28241 (369 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 3BLV-B nrPDB 720 0.0 5YVT-A nrPDB 357 3e-99 2D1C-A nrPDB 279 2e-75 3BLX-A nrPDB 278 2e-75 5GRH-B nrPDB 250 5e-67 3ASJ-A nrPDB 220 9e-58 1WPW-A nrPDB 214 4e-56 4Y1P-A nrPDB 213 7e-56 2IV0-A nrPDB 183 1e-46 2D4V-A nrPDB 183 1e-46 3TY3-A nrPDB 181 6e-46 5HN5-A nrPDB 180 7e-46 1XAD-A nrPDB 178 3e-45 2E5M-A nrPDB 177 5e-45 1IDM-A nrPDB 174 4e-44 1HQS-A nrPDB 171 5e-43 5M2E-A nrPDB 168 3e-42 1AI3-A nrPDB 168 4e-42 1XGV-A nrPDB 160 9e-40 6C0E-A nrPDB 158 3e-39 1V5B-A nrPDB 154 5e-38 3U1H-A nrPDB 154 6e-38 3DMS-A nrPDB 150 1e-36 3FMX-X nrPDB 149 1e-36 2G4O-A nrPDB 139 2e-33 1A05-A nrPDB 137 6e-33 1CNZ-A nrPDB 136 1e-32 5J32-A nrPDB 135 2e-32 1VLC-A nrPDB 134 6e-32 1CM7-A nrPDB 134 8e-32 3VMJ-A nrPDB 131 4e-31 3VML-A nrPDB 128 3e-30 3VMK-A nrPDB 128 4e-30 3UDO-A nrPDB 127 8e-30 4IWH-A nrPDB 114 1e-25 3M6A-A nrPDB 30 1.3 6A2F-A nrPDB 30 2.0 3INP-A nrPDB 28 5.1 >3BLV-B nrPDB Length = 354 Score = 720 bits (1858), Expect = 0.0, Method: Compositional matrix adjust. Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 16 ATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSP 75 ATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSP Sbjct: 1 ATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSP 60 Query: 76 IFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIE 135 IFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIE Sbjct: 61 IFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIE 120 Query: 136 GFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIG 195 GFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIG Sbjct: 121 GFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIG 180 Query: 196 RPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS 255 RPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS Sbjct: 181 RPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS 240 Query: 256 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL 315 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL Sbjct: 241 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL 300 Query: 316 SSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 SSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL Sbjct: 301 SSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 354 >5YVT-A nrPDB Length = 339 Score = 357 bits (917), Expect = 3e-99, Method: Compositional matrix adjust. Identities = 187/337 (55%), Positives = 237/337 (70%), Gaps = 6/337 (1%) Query: 35 GKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIF-VNGLTTIPDPAVQSIT 93 G TV+ I GDGIGPEIS +V KIF AA PI+WE +V+ I G IP A +S+ Sbjct: 3 GVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESMD 62 Query: 94 KNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENT 153 KN + LKGPL TPI GH S+NL LRKTF L+ANVRP SIEG+KT Y +V++V IRENT Sbjct: 63 KNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIRENT 122 Query: 154 EGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADG 213 EGEYSGIEH++ GVVQSIKLIT AS+R+ +AFEYAR R V VHK+ I R++DG Sbjct: 123 EGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSDG 182 Query: 214 LFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLS 273 LF+ +E+++ D+ +D L +V +PS + V V PNLYGDILSDL +GL Sbjct: 183 LFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFD--VLVMPNLYGDILSDLCAGL- 239 Query: 274 AGSLGLTPSANIG-HKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQ 332 G LG+TPS NIG + ++IFE+VHG+APDIAG+D ANPTALLLS+VMML HMGL +HA + Sbjct: 240 IGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAAR 299 Query: 333 IQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 I+ A +TI G ++ T DL G A S FTE + +R+ Sbjct: 300 IEAACFATIKDG-KSLTKDLGGNAKCSDFTEEICRRV 335 >2D1C-A nrPDB Length = 496 Score = 279 bits (713), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 152/342 (44%), Positives = 219/342 (64%), Gaps = 11/342 (3%) Query: 35 GKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDV-SPIFVNGLTT-IPDPAVQSI 92 G+ ++ I GDGIGPE ++ K+ AA P+ +E + + +F G+ + +P ++SI Sbjct: 18 GRKLITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESI 77 Query: 93 TKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY--ENVDLVLIR 150 K V LKGPL TP+G G +S N+TLRK F +ANVRP + T Y +DLV++R Sbjct: 78 RKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAGRGIDLVVVR 137 Query: 151 ENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRL 210 EN E Y+GIEH+ P V Q++KLI+ SE+++R+AFE ARA GR +V KS I +L Sbjct: 138 ENVEDLYAGIEHMQTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKL 197 Query: 211 ADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNS 270 A+G +++++EYPD+ ++DN+ ++V P + V V N+ GDILSDL S Sbjct: 198 AEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQFE--VIVTTNMNGDILSDLTS 255 Query: 271 GLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHA 330 GL G LG PSANIG++++IFEAVHGSAP AG++ NPTA+LLS+VMML ++ A Sbjct: 256 GL-IGGLGFAPSANIGNEVAIFEAVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEFATA 314 Query: 331 DQIQNAVLSTIASGPENRTGDLAGT---ATTSSFTEAVIKRL 369 D I+NA+L T+ G TGD+ G A T+ +TEA+I+ L Sbjct: 315 DLIENALLYTLEEG-RVLTGDVVGYDRGAKTTEYTEAIIQNL 355 >3BLX-A nrPDB Length = 349 Score = 278 bits (711), Expect = 2e-75, Method: Compositional matrix adjust. Identities = 147/344 (42%), Positives = 221/344 (64%), Gaps = 12/344 (3%) Query: 30 PNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPI-FVNGLTTIPDPA 88 P G++TV+ I GDG+G EI+ SV+ IF A N+PI+WE+ ++ G+ A Sbjct: 11 PKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVY----EA 66 Query: 89 VQSITKNLVALKGPLATPIGK-GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLV 147 V+S+ +N + LKG TP + GH SLN+ LRK ++ANV KS++G KT ++DL+ Sbjct: 67 VESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLI 126 Query: 148 LIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTI 207 +IRENTEGE+SG+EH PGVV+S+K++TR +ER+ R+AF++A+ R V VHK+ I Sbjct: 127 VIRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANI 186 Query: 208 QRLADGLFVNVAKEL-SKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILS 266 +L DGLF N+ E+ KEYPD+ + + ++DN+ ++ V P + V V P++YG IL Sbjct: 187 MKLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFD--VLVTPSMYGTILG 244 Query: 267 DLNSGLSAGSLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKANPTALLLSSVMMLNHMG 325 ++ + L G GL AN G ++FE DI GQ+ ANPTA++LSS +MLNH+G Sbjct: 245 NIGAALIGGP-GLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLG 303 Query: 326 LTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 L +A +I AV TIA G ++ T D+ G+++T+ FT +I +L Sbjct: 304 LNEYATRISKAVHETIAEG-KHTTRDIGGSSSTTDFTNEIINKL 346 >5GRH-B nrPDB Length = 354 Score = 250 bits (639), Expect = 5e-67, Method: Compositional matrix adjust. Identities = 139/339 (41%), Positives = 213/339 (62%), Gaps = 12/339 (3%) Query: 35 GKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITK 94 G++TV+ I GDGIGPE+ VK +F A VP+++E VS N A+ +I + Sbjct: 14 GRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS---NADEEDIRNAIMAIRR 70 Query: 95 NLVALKGPLATP--IGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIREN 152 N VALKG + T + H+S N LR + L+ANV KS+ G T ++++D++++REN Sbjct: 71 NRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVREN 130 Query: 153 TEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLAD 212 TEGEYS +EH GVV+S+K+IT+ S R+ YAF+ A+ GR +V VHK+ I +L D Sbjct: 131 TEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGD 190 Query: 213 GLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGL 272 GLF+ +E++ YP +T E ++DN+ +++V+ P + V V PNLYG+I++++ +GL Sbjct: 191 GLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD--VMVMPNLYGNIVNNVCAGL 248 Query: 273 SAGSLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHAD 331 G GL AN GH ++FE A + IA ++ ANPTA LL+S MML+H+ L ++A Sbjct: 249 VGGP-GLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHSYAT 307 Query: 332 QIQNAVLSTIASGPEN-RTGDLAGTATTSSFTEAVIKRL 369 I+ AVL+++ + EN T D+ G TTS + VI+ + Sbjct: 308 SIRKAVLASMDN--ENMHTPDIGGQGTTSEAIQDVIRHI 344 >3ASJ-A nrPDB Length = 334 Score = 220 bits (560), Expect = 9e-58, Method: Compositional matrix adjust. Identities = 136/338 (40%), Positives = 196/338 (57%), Gaps = 14/338 (4%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVS-PIFVNGLTTIPDPAVQSITKN 95 Y + IEGDGIG E+ + +++ A +P+E+ + F T++P+ V+ I Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSC 62 Query: 96 LVALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENT 153 L G +P K G LR+ L+ANVRPAKS + VDLV++RENT Sbjct: 63 HATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKS-RPVPGSRPGVDLVIVRENT 121 Query: 154 EGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPR--VIVVHKSTIQRLA 211 EG Y E V + +I++ ASER+ R A A GRPR + + HK+ + L Sbjct: 122 EGLYVEQERRYL-DVAIADAVISKKASERIGRAALRIAE--GRPRKTLHIAHKANVLPLT 178 Query: 212 DGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSG 271 GLF++ KE++K++P + ++ ++DN +++V P + V V NL GDILSDL +G Sbjct: 179 QGLFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFD--VIVTTNLLGDILSDLAAG 236 Query: 272 LSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHAD 331 L G LGL PS NIG ++FE VHGSAPDIAG+ ANPTA +LS+ MML+++G A Sbjct: 237 L-VGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAK 295 Query: 332 QIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 +++ AV + GP RT DL G ATT +FTEAV++ L Sbjct: 296 RVEKAVDLVLERGP--RTPDLGGDATTEAFTEAVVEAL 331 >1WPW-A nrPDB Length = 336 Score = 214 bits (546), Expect = 4e-56, Method: Compositional matrix adjust. Identities = 135/350 (38%), Positives = 198/350 (56%), Gaps = 33/350 (9%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEW---ESCDVSPIFVNGLTTIPDPAV 89 +TV+ I+GDGIGPEI K+I + N +PIE+ E+ D + +P ++ Sbjct: 2 FTVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRA--LARYGEALPKDSL 59 Query: 90 QSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLI 149 + I K + LKGP +G+ + + LR+ + ++AN+RPAKSI G T Y NVD++++ Sbjct: 60 KIIDKADIILKGP----VGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGNVDILIV 115 Query: 150 RENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQR 209 RENTE Y G EHIV GV +K+ITR ASER+ + +A R +V VHK+ + R Sbjct: 116 RENTEDLYKGFEHIVSDGVAVGMKIITRFASERIAKVGLNFALR-RRKKVTCVHKANVMR 174 Query: 210 LADGLFVNVAKELSK---EYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILS 266 + DGLF + + K EY ++ +D + +V NP + V V N+YGDILS Sbjct: 175 ITDGLFAEACRSVLKGKVEYSEM-----YVDAAAANLVRNPQMFD--VIVTENVYGDILS 227 Query: 267 DLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGL 326 D S + AGSLG+ PSANIG K ++FE VHG+A DIAG++ NPTA LLS MM M Sbjct: 228 DEASQI-AGSLGIAPSANIGDKKALFEPVHGAAFDIAGKNIGNPTAFLLSVSMMYERMYE 286 Query: 327 TNHADQ-------IQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 ++ D+ ++NA+ + + T D+ G ATT + +L Sbjct: 287 LSNDDRYIKASRALENAIY-LVYKERKALTPDVGGNATTDDLINEIYNKL 335 >4Y1P-A nrPDB Length = 337 Score = 213 bits (543), Expect = 7e-56, Method: Compositional matrix adjust. Identities = 132/344 (38%), Positives = 198/344 (57%), Gaps = 29/344 (8%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFVNGL-TTIPDPAVQS 91 + V+ I+GDGIGPE+ K I + N +PIE+ + N +P +++ Sbjct: 3 FVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRV 62 Query: 92 ITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRE 151 I K + LKGP +G+ + + LR + L+AN+RPAKS+ G + + +VD++++RE Sbjct: 63 IEKADMILKGP----VGETAADVVVKLRLMYDLYANLRPAKSLPGLENKFGDVDILVVRE 118 Query: 152 NTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLA 211 NTE Y G+EH++ GV IK+ITR AS R+ + A A + +V+ VHKS + R+ Sbjct: 119 NTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQALR-RKKKVVCVHKSNVMRIT 177 Query: 212 DGLFVNVAKELSK---EYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDL 268 DGLF + + K EY ++ +D + +V NP A+ V V N YGDILSD Sbjct: 178 DGLFAESCRNVLKGKVEYSEM-----YVDAAAANLVRNPQAFD--VIVTENTYGDILSD- 229 Query: 269 NSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMG--- 325 +G AGSLG++PSANIG + S+FE VHG+A DIAG++ ANPTA LLS MML+ M Sbjct: 230 EAGQIAGSLGISPSANIGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELS 289 Query: 326 ----LTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAV 365 N A +++A+ S + G + T D+ G++TT A+ Sbjct: 290 GDIRYNNAAKSLRDAIYSVYSEG-KYLTPDVGGSSTTDEMISAI 332 >2IV0-A nrPDB Length = 412 Score = 183 bits (465), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 131/388 (33%), Positives = 196/388 (50%), Gaps = 65/388 (16%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAANVPIEWESC--------DVSPIFVNGLTTIPDPAVQ 90 + + EGDGIG ++ + ++ AA I E D ++ N L PD + Sbjct: 30 IPYFEGDGIGKDVVPAAIRVLDAAADKIGKEVVWFQVYAGEDAYKLYGNYL---PDDTLN 86 Query: 91 SITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVDLV 147 +I + VALKGPL TP+G G+RSLN+T+R+ L+ANVRP ++G + E V+ V Sbjct: 87 AIKEFRVALKGPLTTPVGGGYRSLNVTIRQVLDLYANVRPVYYLKGVPSPIKHPEKVNFV 146 Query: 148 LIRENTEGEYSGIEHIVCPGVVQSIKL----------------------ITRDASERVIR 185 + RENTE Y+GIE G +++KL I+ A++R++R Sbjct: 147 IFRENTEDVYAGIEW--PRGSEEALKLIRFLKNEFGVTIREDSGIGIKPISEFATKRLVR 204 Query: 186 YAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSK----EY--------------- 226 A YA R V +VHK I + +G F + E++K EY Sbjct: 205 MAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVAKQEFGEYCITEDELWDKYGGKQ 264 Query: 227 PD--LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSAN 284 P+ + ++ + DN +++T Y V PNL GD LSD + L G LG+ P +N Sbjct: 265 PEGKIVVKDRIADNMFQQILTRTDEYD--VIALPNLNGDYLSDAAAAL-IGGLGIAPGSN 321 Query: 285 IGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASG 344 IG I +FE VHGSAP AGQ+K NPTA +L+ +M ++G + ++ I+ AV TI+SG Sbjct: 322 IGDGIGVFEPVHGSAPKYAGQNKVNPTAEILTGALMFEYIGWKDASEMIKKAVEMTISSG 381 Query: 345 --PENRTGDLAGTAT-TSSFTEAVIKRL 369 + + GT T F EAV++ L Sbjct: 382 IVTYDIHRHMGGTKVGTREFAEAVVENL 409 >2D4V-A nrPDB Length = 429 Score = 183 bits (464), Expect = 1e-46, Method: Compositional matrix adjust. Identities = 131/407 (32%), Positives = 199/407 (48%), Gaps = 82/407 (20%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC----DVSPIFVNGLTTIPDP 87 + FIEGDGIG +++ +++ + AA I W ++ G +PD Sbjct: 29 IPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEG-QYLPDE 87 Query: 88 AVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENV 144 + +I + VA+KGPL TP+G G RSLN+ +R+ L+ +RP + EG + E V Sbjct: 88 TMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQDLDLYVCLRPVRYFEGTPSPMRHPEKV 147 Query: 145 DLVLIRENTEGEYSGIEHIVCP--------------GVVQ---------SIKLITRDASE 181 D+V+ REN+E Y+GIE GV + IK ++ + SE Sbjct: 148 DMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVSTEGSE 207 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS-KEYP------------- 227 R+IR +YA G+P V +VHK I + +G F + L+ +E+ Sbjct: 208 RLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGYALAEREFAGRVFTWRQKAAIS 267 Query: 228 -------------------DLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDL 268 L ++ + DN + +++ P Y+ V NL GD +SD Sbjct: 268 KAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRPEDYS--VVATLNLNGDYVSDA 325 Query: 269 NSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTN 328 + G +G+ P AN+ +IFEA HG+APDIAGQ KANP++L+LS+VMML H+G Sbjct: 326 LAA-EVGGIGMAPGANLSDTHAIFEATHGTAPDIAGQGKANPSSLILSAVMMLEHLGWGE 384 Query: 329 HADQIQNAVLSTIASGPENRTGDLAG------TATTSSFTEAVIKRL 369 A I A+ +TIA+G TGDLA +T+ FT A+I+R Sbjct: 385 AAQAIVAAMNATIAAG--EVTGDLAALRGDVPALSTTEFTAALIRRF 429 >3TY3-A nrPDB Length = 366 Score = 181 bits (458), Expect = 6e-46, Method: Compositional matrix adjust. Identities = 129/363 (35%), Positives = 197/363 (54%), Gaps = 37/363 (10%) Query: 33 STGKYTVSFIEGDGIGPEISKSVKKIFSAANVP----IEWESCDVSP---IFVNGLTTIP 85 +T + + I DGIG E+ + +++ N+P ++++ D+ F +P Sbjct: 7 ATRRIVLGLIPADGIGKEVVPAARRLME--NLPAKHKLKFDFIDLDAGWGTFERTGKALP 64 Query: 86 DPAVQSI-TKNLVALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYE 142 + V+ + T+ AL G + +P K G+ S + LRK GL+ANVRP KS++G K + Sbjct: 65 ERTVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKG--K 122 Query: 143 NVDLVLIRENTEGEYSGIEHIV--CPG--VVQSIKLITRDASERVIRYAFEYARAI---- 194 VDLV++RENTE Y E +V PG V ++I+ I+ +AS ++ + AFE A++ Sbjct: 123 PVDLVIVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIR 182 Query: 195 --------GRPRVIVVHKSTIQRLADGLF---VNVAKELSKEYPDLTLETELIDNSVLKV 243 +P V ++HKS + + DGLF A+ L Y + ++ +++D+ V ++ Sbjct: 183 ESGTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRL 242 Query: 244 VTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIA 303 P + V V PNLYGDILSD + L GSLGL PSAN+G + E VHGSAPDIA Sbjct: 243 FREPECFD--VVVAPNLYGDILSDGAASL-IGSLGLVPSANVGDNFVMSEPVHGSAPDIA 299 Query: 304 GQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTE 363 G+ ANP A S +ML MG + A I AV + G + T DL G + T+ T+ Sbjct: 300 GRGIANPVATFRSVALMLEFMGHQDAAADIYTAVDKVLTEG-KVLTPDLGGKSGTNEITD 358 Query: 364 AVI 366 AV+ Sbjct: 359 AVL 361 >5HN5-A nrPDB Length = 353 Score = 180 bits (457), Expect = 7e-46, Method: Compositional matrix adjust. Identities = 122/332 (36%), Positives = 185/332 (55%), Gaps = 19/332 (5%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVS-PIFVNGLTTIPDPAVQSITKN 95 Y V+ I GDGIGPE+ ++ A + +E + +F + I + ++ I ++ Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAVTGRVRFEYYEGGVDVFQECGSPIREEDLEEIRRS 61 Query: 96 LVALKGPLATPIG-KGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTE 154 L G TP G+RSL LTLRK GL+AN+R I +T E +V++REN+E Sbjct: 62 DAVLFGATTTPFDLPGYRSLILTLRKELGLYANLR---IIPDLRTGRE---IVIVRENSE 115 Query: 155 GEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGL 214 G Y GI +V G ++LITR+ +ER+ R+A E A+A G + VHK+ + D Sbjct: 116 GLYFGIGAVVN-GRAVDVRLITREGAERIARFAVEQAKARG-SFITFVHKANVL-TGDKF 172 Query: 215 FVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSA 274 F + +E++ E + + +ID+ +K+V NP + V + NL+GDILSDL + + A Sbjct: 173 FRRIVREVAGE-EGVEVRDAIIDSFTIKLVRNP--WEHGVILSENLFGDILSDLAT-VHA 228 Query: 275 GSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQ 334 GS+G+ PS N G I++FE VHGSAPDIAG+ ANP +LS M+L+++GL I+ Sbjct: 229 GSIGIVPSGNYGDGIALFEPVHGSAPDIAGKGIANPIGAILSGAMLLDYLGLDGSL--IR 286 Query: 335 NAVLSTIASGPENRTGDLAGTATTSSFTEAVI 366 AV + +G T D+ G A T +I Sbjct: 287 AAVRGYVVNG--ELTPDMGGRARTEDVVRGII 316 >1XAD-A nrPDB Length = 345 Score = 178 bits (452), Expect = 3e-45, Method: Compositional matrix adjust. Identities = 125/353 (35%), Positives = 187/353 (52%), Gaps = 33/353 (9%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVS-PIFVNGLTTI-------PDPAVQ 90 V+ + GDGIGPE++++ K+ A + E E ++ +F G I P+P + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALD---EAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRK 59 Query: 91 SITKNLVALKGPLATP-IGKGHRSLN-----LTLRKTFGLFANVRPAKSIEGF------- 137 + + L G + P + R L L++RK LFAN+RP K E Sbjct: 60 GVEEAEAVLLGSVGGPKWDQNPRELRPEKGLLSIRKQLDLFANLRPVKVFESLSDASPLK 119 Query: 138 KTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRP 197 K +NVD V++RE T G Y G + + + ++ ERV R AFE AR R Sbjct: 120 KEYIDNVDFVIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RK 178 Query: 198 RVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVC 257 V+ V K+ + + + + +E+ + YPD+ LE + +D + +V +P+ + V V Sbjct: 179 HVVSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFD--VVVT 235 Query: 258 PNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSS 317 N++GDILSDL S L GSLGL PSA++G +FE VHGSAPDIAG+ ANPTA +LS+ Sbjct: 236 GNIFGDILSDLASVLP-GSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSA 294 Query: 318 VMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 MML H GL A ++++AV + P DL G+A T +FT V++ L Sbjct: 295 AMMLEHAFGLVELARKVEDAVAKALLETPPP---DLGGSAGTEAFTATVLRHL 344 >2E5M-A nrPDB Length = 409 Score = 177 bits (450), Expect = 5e-45, Method: Compositional matrix adjust. Identities = 119/376 (31%), Positives = 187/376 (49%), Gaps = 65/376 (17%) Query: 19 KQPSIGRYTGKPNPSTGKYTVS------FIEGDGIGPEISKSVKKIFSAA-------NVP 65 K+P G K GK+ V +IEGDGIGPEI+ + K+ + A + Sbjct: 4 KEPEDGE---KIKFDKGKWIVPNKPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSRE 60 Query: 66 IEW---ESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTF 122 I+W + + + VN P + + K V LKGPL TPIGKG +S+N+ +R Sbjct: 61 IKWLEVYAGEKAEKLVN--DRFPKETQEMLLKYRVVLKGPLETPIGKGWKSVNVAIRLML 118 Query: 123 GLFANVRPAKSIEGFKTTY---ENVDLVLIRENTEGEYSGIEHIVCPGVVQS-------- 171 L+AN+RP K IEG ++ E VD+++ RENT+ Y GIE+ + Sbjct: 119 DLYANIRPVKYIEGLESPLKHPEKVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKE 178 Query: 172 ------------IKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVA 219 IK++++ ++R+ R A +YA R +V ++HK + + +G F A Sbjct: 179 LKVEIEDDTGIGIKVMSKYKTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWA 238 Query: 220 KELS-KEYPDLTLETELI-----------------DNSVLKVVTNPSAYTDAVSVCPNLY 261 E++ KEY D + E I DN +++ P Y + + PN+ Sbjct: 239 YEVALKEYRDFIVTEEEINQGKPDQGKIILNDRIADNMFQQIIIRPEEYD--IILAPNVN 296 Query: 262 GDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMML 321 GD +SD +G G++G+ ANIG + +FEA+HG+AP AG++ ANPT ++ + +ML Sbjct: 297 GDYISDA-AGALIGNIGMLGGANIGDEGGMFEAIHGTAPKYAGKNVANPTGIIKAGELML 355 Query: 322 NHMGLTNHADQIQNAV 337 MG AD I+ A+ Sbjct: 356 RWMGWNEAADLIEKAI 371 >1IDM-A nrPDB Length = 343 Score = 174 bits (442), Expect = 4e-44, Method: Compositional matrix adjust. Identities = 125/352 (35%), Positives = 189/352 (53%), Gaps = 33/352 (9%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVS-PIFVNGLTTI-------PDPAVQ 90 V+ + GDGIGPE++++ K+ A + E E ++ +F G I P+P + Sbjct: 3 VAVLPGDGIGPEVTEAALKVLRALD---EAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRK 59 Query: 91 SITKNLVALKGPLATP-IGKG----HRSLNLTLRKTFGLFANVRPAKSIEGFK------- 138 + + L G + P G G + L L+LRK+ LFAN+RPAK G + Sbjct: 60 GVEEAEAVLLGSVGGPKWGTGSVRPEQGL-LSLRKSQDLFANLRPAKVFPGLERLSPLKE 118 Query: 139 TTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPR 198 VD++++RE T G Y G + + + ++ ERV R AFE AR R Sbjct: 119 EIARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKH 177 Query: 199 VIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCP 258 V+ V K+ + + + + +E+ + YPD+ LE + +D + +V +P+ + V V Sbjct: 178 VVSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFD--VVVTG 234 Query: 259 NLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSV 318 N++GDILSDL S L GSLGL PSA++G +FE VHGSAPDIAG+ ANPTA +LS+ Sbjct: 235 NIFGDILSDLASVLP-GSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAA 293 Query: 319 MMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 MML H GL A ++++AV + P DL G+A T +FT V++ L Sbjct: 294 MMLEHAFGLVELARKVEDAVAKALLETPPP---DLGGSAGTEAFTATVLRHL 342 >1HQS-A nrPDB Length = 423 Score = 171 bits (432), Expect = 5e-43, Method: Compositional matrix adjust. Identities = 125/404 (30%), Positives = 188/404 (46%), Gaps = 76/404 (18%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESCDVSPIFVNGL-TTIPDPAVQ 90 + FIEGDG GP+I + K+ AA I W+ N +P + Sbjct: 22 IPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAETLD 81 Query: 91 SITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVDLV 147 I + +A+KGPL TP+G G RSLN+ LR+ LF +RP + G + E+ D+V Sbjct: 82 VIREYFIAIKGPLTTPVGGGIRSLNVALRQELDLFVCLRPVRYFTGVPSPVKRPEDTDMV 141 Query: 148 LIRENTEGEYSGIEHIVCPGVVQS-----------------------IKLITRDASERVI 184 + RENTE Y+GIE+ VQ IK ++ + + R++ Sbjct: 142 IFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKIRFPETSGIGIKPVSEEGTSRLV 201 Query: 185 RYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS-KEYPD--------------- 228 R A +YA GR V +VHK I + +G F N EL+ KEY D Sbjct: 202 RAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAEKEYGDKVFTWAQYDRIAEEQ 261 Query: 229 -----------------LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSG 271 + ++ + D + +++T P+ + D V+ NL GD +SD + Sbjct: 262 GKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEF-DVVATM-NLNGDYISDALAA 319 Query: 272 LSAGSLGLTPSANIGHKI--SIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNH 329 G +G+ P ANI ++ +IFEA HG+AP AG DK NP++++LS V++L H+G Sbjct: 320 -QVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDKVNPSSVILSGVLLLEHLGWNEA 378 Query: 330 ADQIQNAVLSTIASGPEN----RTGDLAGTATTSSFTEAVIKRL 369 AD + ++ TIAS R D A S F E +IK + Sbjct: 379 ADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSEFGEELIKNM 422 >5M2E-A nrPDB Length = 418 Score = 168 bits (426), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 116/391 (29%), Positives = 191/391 (48%), Gaps = 63/391 (16%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDPA 88 + FIEGDGIG +IS + K+ AA I W + + + T +P Sbjct: 31 IPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQET 90 Query: 89 VQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYE---NVD 145 + ++ +V++KGPL TP+G G RSLN+ LR+ L+ RP + EG + + +VD Sbjct: 91 LDAVRDYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVKKPGDVD 150 Query: 146 LVLIRENTEGEYSGIEHIV-CPGVVQSIKLIT----------------------RDASER 182 +V+ REN+E Y+G+E P + IK +T ++ ++R Sbjct: 151 MVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQEGTKR 210 Query: 183 VIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY---------------- 226 ++R A +YA R V +VHK I + +G F + E++++ Sbjct: 211 LVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELLDGGPWMQFKN 270 Query: 227 ----PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPS 282 ++ ++ + D + +++ P+ Y D ++ NL GD LSD + G +G+ P Sbjct: 271 PKTGKNVVVKDVIADAMLQQILLRPAEY-DVIATL-NLNGDYLSDALAA-EVGGIGIAPG 327 Query: 283 ANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI----QNAVL 338 AN+ +++FEA HG+AP AGQDK NP +L+LS+ MML HMG T AD I A+ Sbjct: 328 ANLSDSVAMFEATHGTAPKYAGQDKVNPGSLILSAEMMLRHMGWTEAADLIIKGTNGAIA 387 Query: 339 STIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + + R D A + S F +A+I ++ Sbjct: 388 AKTVTYDFERLMDGATLLSCSEFGDAMIAKM 418 >1AI3-A nrPDB Length = 416 Score = 168 bits (425), Expect = 4e-42, Method: Compositional matrix adjust. Identities = 123/393 (31%), Positives = 183/393 (46%), Gaps = 67/393 (17%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDPA 88 + +IEGDGIG +++ ++ K+ AA I W + S +P Sbjct: 29 IPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAET 88 Query: 89 VQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVD 145 + I + VA+KGPL TP+G G RSLN+ LR+ L+ +RP + +G + E D Sbjct: 89 LDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELTD 148 Query: 146 LVLIRENTEGEYSGIEHIVCPGVVQS-----------------------IKLITRDASER 182 +V+ REN+E Y+GIE + IK + + ++R Sbjct: 149 MVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTKR 208 Query: 183 VIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLK 242 ++R A EYA A R V +VHK I + +G F + +L++E ELID Sbjct: 209 LVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLARE----EFGGELIDGGPWL 264 Query: 243 VVTNPS---------AYTDA-------------VSVCPNLYGDILSDLNSGLSAGSLGLT 280 V NP+ DA V C NL GD +SD + G +G+ Sbjct: 265 KVKNPNTGKEIVIKDVIADAFLQQILLRPAEYDVIACMNLNGDYISDALAA-QVGGIGIA 323 Query: 281 PSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI----QNA 336 P ANIG + ++FEA HG+AP AGQDK NP +++LS+ MML HMG T AD I + A Sbjct: 324 PGANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGA 383 Query: 337 VLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + + + R D A S F +A+I+ + Sbjct: 384 INAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >1XGV-A nrPDB Length = 435 Score = 160 bits (405), Expect = 9e-40, Method: Compositional matrix adjust. Identities = 119/387 (30%), Positives = 188/387 (48%), Gaps = 63/387 (16%) Query: 38 TVSFIEGDGIGPEISKS--------VKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAV 89 V+FI GDG+GPE+ +S VKK++ + + WE +P + Sbjct: 37 VVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIVWWELLAGHLAREKCGELLPKATL 96 Query: 90 QSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSI-EGFKTTY-ENVDLV 147 + I VALKGPL TP+G G+RSLN+ +R+ L+AN+RP + + Y + VD+V Sbjct: 97 EGIRLARVALKGPLETPVGTGYRSLNVAIRQALDLYANIRPVRYYGQPAPHKYADRVDMV 156 Query: 148 LIRENTEGEYSGIEHIV-CPGVVQ-------------------SIKLITRDASERVIRYA 187 + RENTE Y+GIE P + +K I+R A+ R++ A Sbjct: 157 IFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIREDAGIGVKPISRFATRRLMERA 216 Query: 188 FEYARAIGRPRVIVVHKSTIQRLADGLFVNVA---------------KELSKEYPDLTLE 232 E+A G V ++HK I + +G F+ A +E+ ++Y + E Sbjct: 217 LEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYEVALEKFREHVVTEQEVQEKYGGVRPE 276 Query: 233 TELI------DNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG 286 +++ DN + +++T P Y V V PNL GD +SD S L G +G+ N+G Sbjct: 277 GKILVNDRIADNMLQQIITRPWDYQ--VIVAPNLNGDYISDAASAL-VGGIGMAAGMNMG 333 Query: 287 HKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGP 345 I++ E VHG+AP AG+D NP+A +LS+ +++ MG ++ A+ + S Sbjct: 334 DGIAVAEPVHGTAPKYAGKDLINPSAEILSASLLIGEFMGWREVKSIVEYAIRKAVQS-- 391 Query: 346 ENRTGDLA------GTATTSSFTEAVI 366 + T DLA TS +TE +I Sbjct: 392 KKVTQDLARHMPGVQPLRTSEYTETLI 418 >6C0E-A nrPDB Length = 419 Score = 158 bits (400), Expect = 3e-39, Method: Compositional matrix adjust. Identities = 113/391 (28%), Positives = 190/391 (48%), Gaps = 63/391 (16%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDPA 88 + FIEGDGIG +++ + ++ AA I W + + G +P Sbjct: 32 IPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKET 91 Query: 89 VQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYE---NVD 145 + ++ K +V++KGPL TP+G G RSLN+ +R+ L+ +RP + G + D Sbjct: 92 LDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKTD 151 Query: 146 LVLIRENTEGEYSGIEHIV----CPGVVQ-------------------SIKLITRDASER 182 +V+ REN+E Y+GIE V+Q +K ++R+ + R Sbjct: 152 MVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTTR 211 Query: 183 VIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS------KEY---PDLTLET 233 +++ A +YA R V +VHK I + +G F + +++ KEY P + + Sbjct: 212 LVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFKN 271 Query: 234 -----ELIDNSVL------KVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPS 282 ++I N V+ +++ P Y+ V NL GD +SD + G +G+ P Sbjct: 272 PKTGKQIIINDVIADAFLQQILLRPEDYS--VIATLNLNGDYISDALAA-QVGGIGIAPG 328 Query: 283 ANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI----QNAVL 338 ANI ++++FEA HG+AP AGQ+K NP +++LS+ MML HMG AD I + A+ Sbjct: 329 ANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAIE 388 Query: 339 STIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + + R A ++S F +A+IK + Sbjct: 389 AKTVTYDFERGMQGATLVSSSGFADAMIKHM 419 >1V5B-A nrPDB Length = 366 Score = 154 bits (390), Expect = 5e-38, Method: Compositional matrix adjust. Identities = 119/367 (32%), Positives = 190/367 (51%), Gaps = 46/367 (12%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGL----------TTIP 85 K ++ + GDGIGPE+ + ++ ++ +F N L T +P Sbjct: 2 KMKLAVLPGDGIGPEVMDAAIRVLKTV-----LDNDGHEAVFENALIGGAAIDEAGTPLP 56 Query: 86 DPAVQSITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF- 137 + + ++ L G + P + + L L LRK GLFAN+RP K+ Sbjct: 57 EETLDICRRSDAILLGAVGGPKWDHNPASLRPEKGL-LGLRKEMGLFANLRPVKAYATLL 115 Query: 138 ------KTTYENVDLVLIRENTEGEYSGI-EHIVCPGVVQSIKLI--TRDASERVIRYAF 188 + ENVDLV++RE T G Y G PG + + + TR+ ER+I AF Sbjct: 116 NASPLKRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTLAYTREEIERIIEKAF 175 Query: 189 EYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPS 248 + A+ I R ++ V K+ + + ++ +A+E +K+YPD+ L L+D++ ++++ NP Sbjct: 176 QLAQ-IRRKKLASVDKANVLE-SSRMWREIAEETAKKYPDVELSHMLVDSTAMQLIANPG 233 Query: 249 AYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANI-GHKISIFEAVHGSAPDIAGQDK 307 + V V N++GDILSDL S ++ GSLG+ PSA++ + ++E VHGSAPDIAGQ K Sbjct: 234 QFD--VIVTENMFGDILSDLASVIT-GSLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGK 290 Query: 308 ANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL----AGTATTSSFT 362 ANP +LS+ +ML + GL A I+ AV + G TGDL +T T Sbjct: 291 ANPLGTVLSAALMLRYSFGLEKEAAAIEKAVDDVLQDG--YCTGDLQVANGKVVSTIELT 348 Query: 363 EAVIKRL 369 + +I++L Sbjct: 349 DRLIEKL 355 >3U1H-A nrPDB Length = 390 Score = 154 bits (389), Expect = 6e-38, Method: Compositional matrix adjust. Identities = 118/343 (34%), Positives = 177/343 (51%), Gaps = 34/343 (9%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIFSAA------NVPIEWESCDVSPIFVNGLTTIPDPAV 89 K ++ + GDGIGPE+ ++ ++ A E+ + I G T +P+ + Sbjct: 23 KKKIAVLPGDGIGPEVMEAAIEVLKAVAERFGHEFEFEYGLIGGAAIDEAG-TPLPEETL 81 Query: 90 QSITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF----- 137 + L G + P + + L L +RK LFAN+RP K + Sbjct: 82 DVCRGSDAILLGAVGGPKWDQNPSELRPEKGL-LGIRKGLDLFANLRPVKVYDSLADASP 140 Query: 138 --KTTYENVDLVLIRENTEGEYSGI---EHIVCPGVVQSIKLITRDASERVIRYAFEYAR 192 K E VDLV++RE T G Y G + L TR+ ER+IR AFE A Sbjct: 141 LKKEVIEGVDLVIVRELTGGLYFGEPSERYEEGEEAAVDTLLYTREEIERIIRKAFELA- 199 Query: 193 AIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTD 252 + +V V K+ + + L+ VA+E++KEYPD+ LE L+DN+ ++++ NP + Sbjct: 200 LTRKKKVTSVDKANVLE-SSRLWREVAEEVAKEYPDVELEHMLVDNAAMQLIRNPRQFD- 257 Query: 253 AVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG-HKISIFEAVHGSAPDIAGQDKANPT 311 V V N++GDILSD + + GSLG+ PSA++ + ++E VHGSAPDIAG+ ANP Sbjct: 258 -VIVTENMFGDILSD-EASMITGSLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPL 315 Query: 312 ALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLA 353 A +LS+ MML + GL A I+ AV +A G RT D+A Sbjct: 316 ATILSAAMMLRYSFGLEEEAKAIEKAVEKVLAEG--YRTADIA 356 >3DMS-A nrPDB Length = 427 Score = 150 bits (378), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 106/364 (29%), Positives = 176/364 (48%), Gaps = 69/364 (18%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESCDVSPIFVNGLTT-------- 83 + +IEGDG G +I+ + K+ AA I W I+ T Sbjct: 39 IPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKIHWME-----IYAGEKATKVYGPDVW 93 Query: 84 IPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY-- 141 +P+ +Q + + +V++KGPL TP+G G RSLN+ LR+ L+ +RP + +G + Sbjct: 94 LPEETLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPIQYFKGVPSPVRE 153 Query: 142 -ENVDLVLIRENTEGEYSGIEHIV----CPGVVQ-------------------SIKLITR 177 E ++V+ REN+E Y+GIE V++ IK +++ Sbjct: 154 PEKTNMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEMGVKKIRFPQTSGIGIKPVSK 213 Query: 178 DASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVA-----KELSKEYPD---- 228 + +ER++R A +YA R V +VHK I + +G F + KE E D Sbjct: 214 EGTERLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRDAGYALAQKEFGAELIDGGPW 273 Query: 229 -----------LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSL 277 + ++ + D + +++ P+ Y D ++ NL GD +SD + G + Sbjct: 274 MKFKNPKTGNEIVVKDSIADAFLQQILLRPAEY-DVIATL-NLNGDYISDALAA-QVGGI 330 Query: 278 GLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAV 337 G+ P AN+ +++FEA HG+AP AG+D NP + +LS+ MML H+G T AD I +A+ Sbjct: 331 GIAPGANLSDSVAMFEATHGTAPKYAGKDYVNPGSEILSAEMMLRHLGWTEAADVIISAM 390 Query: 338 LSTI 341 +I Sbjct: 391 EKSI 394 >3FMX-X nrPDB Length = 364 Score = 149 bits (377), Expect = 1e-36, Method: Compositional matrix adjust. Identities = 109/359 (30%), Positives = 170/359 (47%), Gaps = 38/359 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVP---------IEWESCDVSPIFVNGLTTIPDP 87 + ++ I GDGIG E+ ++ AA + EW SCD ++ +PD Sbjct: 6 FRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDY---YLQHGKMMPDD 62 Query: 88 AVQSITKNLVALKGPLATPIG-KGHRSLN---LTLRKTFGLFANVRPAKSIEGFKTTYEN 143 + + + G + P H SL L R+ F + N+RP + G N Sbjct: 63 WAEQLKQYDAIYFGAVGWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALAN 122 Query: 144 -----VDLVLIRENTEGEYSGIEHIVCPGVVQSI----KLITRDASERVIRYAFEYARAI 194 +D V++RENTEGEYS + I+ I + TR +R+++YAF+ A Sbjct: 123 RKVGDIDFVVVRENTEGEYSSLGGIMFENTENEIVIQESIFTRRGVDRILKYAFDLAEKR 182 Query: 195 GRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAV 254 R V KS ++ + + ++ YP ++ + + ID + V P + V Sbjct: 183 ERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFD--V 240 Query: 255 SVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKI---SIFEAVHGSAPDIAGQDKANPT 311 V NL+GDILSDL AG++G+ PSAN+ + S+FE VHGSAPDI G++ ANP Sbjct: 241 VVASNLFGDILSDLGPA-CAGTIGIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPI 299 Query: 312 ALLLSSVMMLNHMGLTNH-----ADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAV 365 A++ S +ML +G + D + NA+ IA G + T D+ GT +T A+ Sbjct: 300 AMIWSGALMLEFLGQGDERYQRAHDDMLNAIERVIADG--SVTPDMGGTLSTQQVGAAI 356 >2G4O-A nrPDB Length = 337 Score = 139 bits (351), Expect = 2e-33, Method: Compositional matrix adjust. Identities = 104/319 (32%), Positives = 166/319 (52%), Gaps = 18/319 (5%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPI-FVNGLTTIPDPAVQSITKNLV 97 ++ I GDGIGPE++ K+ A ++ S D+ F +PD V + + Sbjct: 4 LAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHDA 63 Query: 98 ALKGPL---ATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYEN---VDLVLIRE 151 L G + + P G R L L LR N+RPA+ G + +D V++RE Sbjct: 64 ILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVRE 123 Query: 152 NTEGEYSGIEHIVCPG----VVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTI 207 TEG Y+G + G V + + T RV+ AFE AR R + +VHK+ + Sbjct: 124 GTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERARRR-RKHLTLVHKTNV 182 Query: 208 QRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSD 267 A GL++ E+ + YPD+ + + +D + + ++T+P + V V NL+GDI++D Sbjct: 183 LTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFD--VIVTDNLFGDIITD 240 Query: 268 LNSGLSAGSLGLTPSANIGH---KISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHM 324 L + + G +GL S NI S+FE VHGSAPDIAGQ A+PTA ++S ++L+H+ Sbjct: 241 LAAAVC-GGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSHL 299 Query: 325 GLTNHADQIQNAVLSTIAS 343 G + A ++ AV + +A+ Sbjct: 300 GEHDAAARVDRAVEAHLAT 318 >1A05-A nrPDB Length = 358 Score = 137 bits (346), Expect = 6e-33, Method: Compositional matrix adjust. Identities = 111/352 (31%), Positives = 175/352 (49%), Gaps = 34/352 (9%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAANVPIEWE-SCDVSPIFVNGLTTIPDP--------AV 89 ++ GDGIGPEI + +++ A + C + L DP A+ Sbjct: 4 IAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQLAM 63 Query: 90 QSITKNLVALKGPL--ATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGF-------KTT 140 + L A+ GP A P K L LRK L+AN+RPA+ Sbjct: 64 AADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRPEL 123 Query: 141 YENVDLVLIRENTE----GEYSGIEHIVCPGVVQSIKLITRDASE--RVIRYAFEYARAI 194 +VD++++RE T G+ G+E V G + + D E R+ AF A+ Sbjct: 124 VRDVDILVVRELTGDIYFGQPRGLE--VIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQG- 180 Query: 195 GRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAV 254 R ++ V K+ + L+ V E++++YPD+ L +DN+ ++++ P+ + V Sbjct: 181 RRKQLCSVDKANVLETTR-LWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFD--V 237 Query: 255 SVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALL 314 + N++GDILSD S L+ GS+G+ PSA++G +++E +HGSAPDIAGQDKANP A + Sbjct: 238 LLTGNMFGDILSDEASQLT-GSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATI 296 Query: 315 LSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAV 365 LS MML H + A +++ AV + G RT D+A T T+A+ Sbjct: 297 LSVAMMLRHSLNAEPWAQRVEAAVQRVLDQG--LRTADIAAPGTPVIGTKAM 346 >1CNZ-A nrPDB Length = 363 Score = 136 bits (342), Expect = 1e-32, Method: Compositional matrix adjust. Identities = 112/354 (31%), Positives = 175/354 (49%), Gaps = 35/354 (9%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAA----NVPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ K+ A ++ I DV I + N +P V+ Sbjct: 5 YHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEG 64 Query: 92 ITKNLVALKGPLATPIGKG-------HRSLNLTLRKTFGLFANVRPAKSIEGFKT----- 139 + L G + P + R L LRK F LF+N+RPAK +G + Sbjct: 65 CEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 140 ---TYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIK-----LITRDASERVIRYAFEYA 191 D++ +RE T G Y G + G Q K + R ER+ R AFE A Sbjct: 125 ADIAANGFDILCVRELTGGIYFG-QPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESA 183 Query: 192 RAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYT 251 R R +V + K+ + + + L+ + +++K YPD+ L IDN+ ++++ +PS + Sbjct: 184 RK-RRRKVTSIDKANVLQ-SSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQFD 241 Query: 252 DAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAPDIAGQDKANP 310 V +C NL+GDILSD + GS+G+ PSA++ + ++E GSAPDIAG++ ANP Sbjct: 242 --VLLCSNLFGDILSD-ECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANP 298 Query: 311 TALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTE 363 A +LS ++L + + + A I+ A+ + G RTGDLA A S E Sbjct: 299 IAQILSLALLLRYSLDANDAATAIEQAINRALEEGV--RTGDLARGAAAVSTDE 350 >5J32-A nrPDB Length = 403 Score = 135 bits (341), Expect = 2e-32, Method: Compositional matrix adjust. Identities = 109/358 (30%), Positives = 178/358 (49%), Gaps = 54/358 (15%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIFSAA-----------NVPIEWESCDVSPIFVNGLTTI 84 +YT++ + GDGIGPE+ K + A +PI + D+ + + Sbjct: 40 RYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGV------PL 93 Query: 85 PDPAVQSITKNLVALKGPLATPIGKGHRSLN-----------LTLRKTFGLFANVRPAKS 133 P+ + + ++ L G + G++ N L +R +FAN+RPA Sbjct: 94 PEETISAAKESDAVLLGAIG-----GYKWDNNEKHLRPEKGLLQIRAALKVFANLRPATV 148 Query: 134 IEGF-------KTTYENVDLVLIRENTEGEYSGIEHIV-----CPGVVQSIKLITRDASE 181 + + E VDL+++RE T G Y G + V + ++ + Sbjct: 149 LPQLVDASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEID 208 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVL 241 R+ R AFE AR R ++ V K+ + A L+ L+ EYPD+ L +DN+ + Sbjct: 209 RIARVAFETARKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAM 266 Query: 242 KVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAP 300 ++V +P + D + V N++GDILSD + + GS+G+ PSA++ +FE +HGSAP Sbjct: 267 QLVRDPKQF-DTI-VTNNIFGDILSD-EASMITGSIGMLPSASLSDSGPGLFEPIHGSAP 323 Query: 301 DIAGQDKANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTAT 357 DIAGQDKANP A +LS+ M+L + +G A +I++AVL + +G RTGD+ T Sbjct: 324 DIAGQDKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNG--FRTGDIYSAGT 379 >1VLC-A nrPDB Length = 366 Score = 134 bits (337), Expect = 6e-32, Method: Compositional matrix adjust. Identities = 97/267 (36%), Positives = 141/267 (52%), Gaps = 21/267 (7%) Query: 116 LTLRKTFGLFANVRPAKSIEGF--------KTTYENVDLVLIRENTEGEYSGIEHIVCPG 167 L LRK L+AN+RP K K VDLV +RE + G Y G + Sbjct: 104 LALRKMLNLYANIRPIKVYRSLVHVSPLKEKVIGSGVDLVTVRELSYGVYYGQPRGLDEE 163 Query: 168 VVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYP 227 + R ER+ R AFE A+ R +V V K+ + + L+ V E+++EYP Sbjct: 164 KGFDTMIYDRKTVERIARTAFEIAKN-RRKKVTSVDKANVL-YSSMLWRKVVNEVAREYP 221 Query: 228 DLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH 287 D+ L +DN+ ++++ PS + V + N++GDILSD ++ L GSLGL PSA+ G Sbjct: 222 DVELTHIYVDNAAMQLILKPSQFD--VILTTNMFGDILSDESAALP-GSLGLLPSASFGD 278 Query: 288 KISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPE 346 K +++E GSAPDIAG++ ANP A +LS MML H G+ A +I+ AV I G Sbjct: 279 K-NLYEPAGGSAPDIAGKNIANPIAQILSLAMMLEHSFGMVEEARKIERAVELVIEEG-- 335 Query: 347 NRTGDLA----GTATTSSFTEAVIKRL 369 RT D+A +TS + + K+L Sbjct: 336 YRTRDIAEDPEKAVSTSQMGDLICKKL 362 >1CM7-A nrPDB Length = 363 Score = 134 bits (336), Expect = 8e-32, Method: Compositional matrix adjust. Identities = 112/354 (31%), Positives = 173/354 (48%), Gaps = 35/354 (9%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ K+ A + I DV + N +P V+ Sbjct: 5 YHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEG 64 Query: 92 ITKNLVALKGPLATPIGKG-------HRSLNLTLRKTFGLFANVRPAKSIEGFKT----- 139 + L G + P + R L LRK F LF+N+RPAK +G + Sbjct: 65 CEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 140 ---TYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIK-----LITRDASERVIRYAFEYA 191 D++ +RE T G Y G + G Q K + R ER+ R AFE A Sbjct: 125 ADIAANGFDILCVRELTGGIYFG-QPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESA 183 Query: 192 RAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYT 251 R R +V + K+ + + + L+ + E++ EYPD+ L IDN+ ++++ +PS + Sbjct: 184 RK-RRHKVTSIDKANVLQ-SSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFD 241 Query: 252 DAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAPDIAGQDKANP 310 V +C NL+GDILSD + GS+G+ PSA++ + ++E GSAPDIAG++ ANP Sbjct: 242 --VLLCSNLFGDILSD-ECAMITGSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANP 298 Query: 311 TALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTE 363 A +LS ++L + + + A I+ A+ + G RTGDLA A S E Sbjct: 299 IAQILSLALLLRYSLDADDAACAIERAINRALEEGI--RTGDLARGAAAVSTDE 350 >3VMJ-A nrPDB Length = 375 Score = 131 bits (330), Expect = 4e-31, Method: Compositional matrix adjust. Identities = 106/335 (31%), Positives = 165/335 (49%), Gaps = 33/335 (9%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ +K+ A + IE+ DV I + N +P+ ++ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 92 ITKNLVALKGPLATPIGKG-------HRSLNLTLRKTFGLFANVRPAKSIEGFK------ 138 L G + P + R L LR F LF N+RPAK +G + Sbjct: 74 CEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLR 133 Query: 139 --TTYENVDLVLIRENTEGEYSGIE-----HIVCPGVVQSIKLITRDASERVIRYAFEYA 191 + D++ +RE T G Y G +++ R+ S R+ R AFE A Sbjct: 134 SDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREIS-RIARIAFEAA 192 Query: 192 RAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYT 251 R R +V V K+ + + L+ V +E++ ++PD+ LE IDN+ ++++ P + Sbjct: 193 RGR-RKKVTSVDKANVLACSV-LWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFD 250 Query: 252 DAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAPDIAGQDKANP 310 V +C NL+GDILSD + L+ GS+GL SA++ +FE GSAPDIAG+ ANP Sbjct: 251 --VMLCSNLFGDILSDEIAMLT-GSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANP 307 Query: 311 TALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASG 344 A +LS+ +ML H + A I+ AV + SG Sbjct: 308 IAQILSAALMLRHSLKQEEAASAIERAVTKALNSG 342 >3VML-A nrPDB Length = 375 Score = 128 bits (322), Expect = 3e-30, Method: Compositional matrix adjust. Identities = 105/339 (30%), Positives = 167/339 (49%), Gaps = 41/339 (12%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ +K+ A + IE+ DV I + N +P+ ++ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 92 ITKNLVALKGPLATPIGKG-------HRSLNLTLRKTFGLFANVRPAKSIEGFK------ 138 L G + P + R L LR F LF N+RPAK G + Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 139 --TTYENVDLVLIRENTEGEYSGIEHIVCPGVVQ---------SIKLITRDASERVIRYA 187 + + D++ +RE T G Y G P Q +R R+ + A Sbjct: 134 SDISEKGFDILCVRELTGGIYFGK-----PKGRQGEGENEEAFDTMRYSRKEIRRIAKIA 188 Query: 188 FEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNP 247 FE A+ R +V V K+ + + L+ V +E++K+YPD+ LE IDN+ ++++ P Sbjct: 189 FESAQGR-RKKVTSVDKANVLACSV-LWREVVEEVAKDYPDVELEHIYIDNATMQLLRRP 246 Query: 248 SAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAPDIAGQD 306 + + V +C NL+GDI+SD + L+ GS+GL S ++ + ++E GSAPDIAGQ Sbjct: 247 NEFD--VMLCSNLFGDIVSDEIAMLT-GSMGLLASISMNSQGFGMYEPAGGSAPDIAGQG 303 Query: 307 KANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASG 344 ANP A +LS+ ++L H + L + A I+ AV + SG Sbjct: 304 IANPVAQILSAALLLRHSLKLEDAALAIEAAVSKALNSG 342 >3VMK-A nrPDB Length = 375 Score = 128 bits (321), Expect = 4e-30, Method: Compositional matrix adjust. Identities = 103/339 (30%), Positives = 168/339 (49%), Gaps = 41/339 (12%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAA----NVPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ +K+ +A ++ IE+ DV + N +P+ ++ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRFDLSIEYSEYDVGGAAIDNHGCPLPEATLKG 73 Query: 92 ITKNLVALKGPLATPIGKG-------HRSLNLTLRKTFGLFANVRPAKSIEGFK------ 138 L G + P + R L LR F LF N+RPAK G + Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 139 --TTYENVDLVLIRENTEGEYSGIEHIVCPGVVQ---------SIKLITRDASERVIRYA 187 + + D++ +RE T G Y G P Q +R R+ + A Sbjct: 134 SDISEKGFDILCVRELTGGIYFGK-----PKGRQGEGENEEAFDTMRYSRKEIRRIAKIA 188 Query: 188 FEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNP 247 FE A+ R +V V K+ + + L+ V +E++K+YPD+ LE IDN+ ++++ P Sbjct: 189 FESAQG-RRKKVTSVDKANVLACSV-LWREVVEEVAKDYPDVELEHIYIDNATMQLLRRP 246 Query: 248 SAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK-ISIFEAVHGSAPDIAGQD 306 + + V +C NL+GDI+SD + L+ GS+GL S ++ + ++E GSAPDIAGQ Sbjct: 247 NEFD--VMLCSNLFGDIVSDEIAMLT-GSMGLLASISMNSQGFGMYEPAGGSAPDIAGQG 303 Query: 307 KANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASG 344 ANP A +LS+ ++L H + L + A I+ AV ++ G Sbjct: 304 IANPVAQILSAALLLRHSLKLEDAALAIEAAVSKALSDG 342 >3UDO-A nrPDB Length = 361 Score = 127 bits (319), Expect = 8e-30, Method: Compositional matrix adjust. Identities = 102/355 (28%), Positives = 171/355 (48%), Gaps = 28/355 (7%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFS----AANVPIEWESCDVSPIFVNGL-TTIPDPAVQS 91 Y V+ + GDGIGP + K KI + N E + ++ + D ++ Sbjct: 7 YKVAVLAGDGIGPLVMKEALKILTFIAQKYNFSFELNEAKIGGASIDAYGVALSDETLKL 66 Query: 92 ITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF------- 137 ++ L G + P + R+ L LRK F LFAN+RP K E Sbjct: 67 CEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLK 126 Query: 138 -KTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGR 196 + + VD++ +RE T G Y G + + + ++ T+ ER+ R AFE AR I + Sbjct: 127 NEIIQKGVDILCVRELTGGIYFGKQDLGKESAYDT-EIYTKKEIERIARIAFESAR-IRK 184 Query: 197 PRVIVVHKSTIQRLADG-LFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS 255 +V ++ K+ + LA L+ V ++K+Y D+ LE +DN+ +++V NPS + V Sbjct: 185 KKVHLIDKANV--LASSILWREVVANVAKDYQDINLEYMYVDNAAMQIVKNPSIFD--VM 240 Query: 256 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL 315 +C NL+GDILSD + ++ L+ ++ ++E GSAPDIA + ANP A +L Sbjct: 241 LCSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIANPIAQIL 300 Query: 316 SSVMMLNHMGLTNHADQ-IQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 S+ +ML + A Q I+NA+ +A G + + T + +++ L Sbjct: 301 SAALMLKYSFKEEQAAQDIENAISLALAQGKMTKDLNAKSYLNTDEMGDCILEIL 355 >4IWH-A nrPDB Length = 363 Score = 114 bits (284), Expect = 1e-25, Method: Compositional matrix adjust. Identities = 112/367 (30%), Positives = 180/367 (49%), Gaps = 50/367 (13%) Query: 39 VSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTT----IPDPAVQSITK 94 ++ + GDGIGPEI K+ +A + E E +P+ G +PD A ++ K Sbjct: 11 IAVLPGDGIGPEIVNEAVKVLNALDEKFELEH---APVGGAGYEASGHPLPD-ATLALAK 66 Query: 95 NLVALKGPLATPIGKG-----HRSLN-----LTLRKTFGLFANVRPA----KSIEGFKTT 140 A+ L +G R+L L LRK LFAN RPA + ++ Sbjct: 67 EADAI---LFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLK 123 Query: 141 YE---NVDLVLIRENTEGEYSGIEHIV-----CPGVVQSIKLITRDASE----RVIRYAF 188 E +D++++RE Y G V P + T SE R+ AF Sbjct: 124 PELVAGLDILIVRELNGDIYFGQPRGVRAAPDGPFAGEREGFDTMRYSEPEVRRIAHVAF 183 Query: 189 EYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPS 248 + A+ + +++ V KS + + + +V ++SKEY D+ L +DN+ +++ P Sbjct: 184 QAAQKRAK-KLLSVDKSNVLETSQ-FWRDVMIDVSKEYADVELSHMYVDNAAMQLAKAPK 241 Query: 249 AYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG-HKISIFEAVHGSAPDIAGQDK 307 + V V N++GDILSD S L+ GS+G+ PSA++ + ++E HGSAPDIAG+ Sbjct: 242 QFD--VIVTGNMFGDILSDEASMLT-GSIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGI 298 Query: 308 ANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTAT----TSSFT 362 ANP A +LS+ M+L + + AD+I+ AV + + G RTGD+A T++ Sbjct: 299 ANPLATILSAAMLLRYSLNRAEQADRIERAVKTVLEQG--YRTGDIATPGCRQVGTAAMG 356 Query: 363 EAVIKRL 369 +AV+ L Sbjct: 357 DAVVAAL 363 >3M6A-A nrPDB Length = 543 Score = 30.4 bits (67), Expect = 1.3, Method: Compositional matrix adjust. Identities = 24/63 (38%), Positives = 30/63 (47%), Gaps = 12/63 (19%) Query: 88 AVQSITKNLVALKGP---LATPIGKGHRSLNLTLRKTFGL------FANVRPAKSIEGFK 138 AVQ +TK +LKGP LA P G G SL ++ K+ G VR I G + Sbjct: 98 AVQKLTK---SLKGPILCLAGPPGVGKTSLAKSIAKSLGRKFVRISLGGVRDESEIRGHR 154 Query: 139 TTY 141 TY Sbjct: 155 RTY 157 >6A2F-A nrPDB Length = 358 Score = 29.6 bits (65), Expect = 2.0, Method: Compositional matrix adjust. Identities = 26/72 (36%), Positives = 38/72 (52%), Gaps = 7/72 (9%) Query: 228 DLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDI-LSDLNSGLSAGSLGLTPSANIG 286 DL + + NS V+T P+A+ D + LYG L+DL SA LGL P+ ++G Sbjct: 183 DLDFDQRSLANSA-AVLTIPAAHMDWLRPGIMLYGSTPLADL----SAAELGLKPAMSLG 237 Query: 287 HK-ISIFEAVHG 297 + IS+ E G Sbjct: 238 AQLISLREVAVG 249 >3INP-A nrPDB Length = 246 Score = 28.5 bits (62), Expect = 5.1, Method: Compositional matrix adjust. Identities = 23/74 (31%), Positives = 35/74 (47%), Gaps = 5/74 (6%) Query: 106 PIGKGHRSLNLTLRKTFGLFANV--RPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHI 163 P H +L L K+FG+ A + PA I+ K N+D VLI G + G + I Sbjct: 117 PEASEHIDRSLQLIKSFGIQAGLALNPATGIDCLKYVESNIDRVLIMSVNPG-FGGQKFI 175 Query: 164 VCPGVVQSIKLITR 177 P ++ K I++ Sbjct: 176 --PAMLDKAKEISK 187 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 3BLV-B nrPDB 508 e-144 5YVT-A nrPDB 442 e-124 2D1C-A nrPDB 425 e-119 1AI3-A nrPDB 408 e-114 3BLX-A nrPDB 406 e-114 5M2E-A nrPDB 403 e-113 3ASJ-A nrPDB 401 e-112 2IV0-A nrPDB 400 e-112 5GRH-B nrPDB 396 e-110 6C0E-A nrPDB 394 e-110 3U1H-A nrPDB 389 e-109 2E5M-A nrPDB 388 e-108 1CNZ-A nrPDB 388 e-108 1HQS-A nrPDB 386 e-108 3DMS-A nrPDB 386 e-108 1XAD-A nrPDB 383 e-107 1IDM-A nrPDB 382 e-106 1CM7-A nrPDB 382 e-106 3VMJ-A nrPDB 381 e-106 3VML-A nrPDB 379 e-105 3VMK-A nrPDB 378 e-105 2D4V-A nrPDB 377 e-105 1VLC-A nrPDB 376 e-105 1WPW-A nrPDB 373 e-103 4Y1P-A nrPDB 372 e-103 1V5B-A nrPDB 365 e-101 3FMX-X nrPDB 363 e-100 3TY3-A nrPDB 361 e-100 3UDO-A nrPDB 360 e-100 1A05-A nrPDB 360 e-100 1XGV-A nrPDB 358 2e-99 4IWH-A nrPDB 356 7e-99 5HN5-A nrPDB 351 2e-97 5J32-A nrPDB 351 2e-97 2G4O-A nrPDB 326 1e-89 Sequences not found previously or not previously below threshold: 1ZOR-A nrPDB 83 1e-16 2QFY-A nrPDB 71 9e-13 5I96-A nrPDB 67 1e-11 4AOY-A nrPDB 62 3e-10 4HCX-A nrPDB 61 7e-10 2UXQ-A nrPDB 57 1e-08 3US8-A nrPDB 52 5e-07 5Z16-A nrPDB 37 0.010 3WDK-A nrPDB 37 0.016 4MB2-A nrPDB 36 0.023 1J1W-A nrPDB 36 0.023 4ZDA-A nrPDB 34 0.096 4YYC-A nrPDB 33 0.16 6G3U-A nrPDB 33 0.17 5KVU-A nrPDB 33 0.18 4JQP-A nrPDB 31 0.62 1YE8-A nrPDB 31 0.77 4A8J-A nrPDB 31 0.91 4V6W-CM nrPDB 31 0.94 1F1E-A nrPDB 30 1.3 5NAV-A nrPDB 30 1.5 2F6U-A nrPDB 30 1.7 4ATY-A nrPDB 30 2.3 2XIG-A nrPDB 29 3.3 1MZB-A nrPDB 29 3.4 6NF8-L nrPDB 29 3.5 6GAW-AL nrPDB 29 3.5 5AJ4-AL nrPDB 29 3.5 1PW4-A nrPDB 29 3.8 1VBH-A nrPDB 29 4.1 2RFG-A nrPDB 29 4.3 2FTP-A nrPDB 29 4.4 >3BLV-B nrPDB Length = 354 Score = 508 bits (1309), Expect = e-144, Method: Composition-based stats. Identities = 354/354 (100%), Positives = 354/354 (100%) Query: 16 ATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSP 75 ATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSP Sbjct: 1 ATVKQPSIGRYTGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSP 60 Query: 76 IFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIE 135 IFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIE Sbjct: 61 IFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIE 120 Query: 136 GFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIG 195 GFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIG Sbjct: 121 GFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIG 180 Query: 196 RPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS 255 RPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS Sbjct: 181 RPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVS 240 Query: 256 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL 315 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL Sbjct: 241 VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLL 300 Query: 316 SSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 SSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL Sbjct: 301 SSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 354 >5YVT-A nrPDB Length = 339 Score = 442 bits (1138), Expect = e-124, Method: Composition-based stats. Identities = 187/338 (55%), Positives = 237/338 (70%), Gaps = 6/338 (1%) Query: 34 TGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTT-IPDPAVQSI 92 G TV+ I GDGIGPEIS +V KIF AA PI+WE +V+ I G IP A +S+ Sbjct: 2 GGVQTVTLIPGDGIGPEISAAVMKIFDAAKAPIQWEERNVTAIQGPGGKWMIPSEAKESM 61 Query: 93 TKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIREN 152 KN + LKGPL TPI GH S+NL LRKTF L+ANVRP SIEG+KT Y +V++V IREN Sbjct: 62 DKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIVTIREN 121 Query: 153 TEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLAD 212 TEGEYSGIEH++ GVVQSIKLIT AS+R+ +AFEYAR R V VHK+ I R++D Sbjct: 122 TEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSD 181 Query: 213 GLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGL 272 GLF+ +E+++ D+ +D L +V +PS + V V PNLYGDILSDL +GL Sbjct: 182 GLFLQKCREVAESCKDIKFNEMYLDTVCLNMVQDPSQFD--VLVMPNLYGDILSDLCAGL 239 Query: 273 SAGSLGLTPSANIG-HKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHAD 331 G LG+TPS NIG + ++IFE+VHG+APDIAG+D ANPTALLLS+VMML HMGL +HA Sbjct: 240 -IGGLGVTPSGNIGANGVAIFESVHGTAPDIAGKDMANPTALLLSAVMMLRHMGLFDHAA 298 Query: 332 QIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 +I+ A +TI G ++ T DL G A S FTE + +R+ Sbjct: 299 RIEAACFATIKDG-KSLTKDLGGNAKCSDFTEEICRRV 335 >2D1C-A nrPDB Length = 496 Score = 425 bits (1093), Expect = e-119, Method: Composition-based stats. Identities = 150/342 (43%), Positives = 213/342 (62%), Gaps = 11/342 (3%) Query: 35 GKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTT--IPDPAVQSI 92 G+ ++ I GDGIGPE ++ K+ AA P+ +E + +P ++SI Sbjct: 18 GRKLITVIPGDGIGPECVEATLKVLEAAKAPLAYEVREAGASVFRRGIASGVPQETIESI 77 Query: 93 TKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY--ENVDLVLIR 150 K V LKGPL TP+G G +S N+TLRK F +ANVRP + T Y +DLV++R Sbjct: 78 RKTRVVLKGPLETPVGYGEKSANVTLRKLFETYANVRPVREFPNVPTPYAGRGIDLVVVR 137 Query: 151 ENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRL 210 EN E Y+GIEH+ P V Q++KLI+ SE+++R+AFE ARA GR +V KS I +L Sbjct: 138 ENVEDLYAGIEHMQTPSVAQTLKLISWKGSEKIVRFAFELARAEGRKKVHCATKSNIMKL 197 Query: 211 ADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNS 270 A+G +++++EYPD+ ++DN+ ++V P + V V N+ GDILSDL S Sbjct: 198 AEGTLKRAFEQVAQEYPDIEAVHIIVDNAAHQLVKRPEQFE--VIVTTNMNGDILSDLTS 255 Query: 271 GLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHA 330 GL G LG PSANIG++++IFEAVHGSAP AG++ NPTA+LLS+VMML ++ A Sbjct: 256 GL-IGGLGFAPSANIGNEVAIFEAVHGSAPKYAGKNVINPTAVLLSAVMMLRYLEEFATA 314 Query: 331 DQIQNAVLSTIASGPENRTGDLAGT---ATTSSFTEAVIKRL 369 D I+NA+L T+ G TGD+ G A T+ +TEA+I+ L Sbjct: 315 DLIENALLYTLEEG-RVLTGDVVGYDRGAKTTEYTEAIIQNL 355 >1AI3-A nrPDB Length = 416 Score = 408 bits (1050), Expect = e-114, Method: Composition-based stats. Identities = 117/392 (29%), Positives = 186/392 (47%), Gaps = 63/392 (16%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDP 87 + +IEGDGIG +++ ++ K+ AA I W + S +P Sbjct: 28 IIPYIEGDGIGVDVTPAMLKVVDAAVEKAYKGERKISWMEIYTGEKSTQVYGQDVWLPAE 87 Query: 88 AVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENV 144 + I + VA+KGPL TP+G G RSLN+ LR+ L+ +RP + +G + E Sbjct: 88 TLDLIREYRVAIKGPLTTPVGGGIRSLNVALRQELDLYICLRPVRYYQGTPSPVKHPELT 147 Query: 145 DLVLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASE 181 D+V+ REN+E Y+GIE + IK + + ++ Sbjct: 148 DMVIFRENSEDIYAGIEWKADSADAEKVIKFLREEMGVKKIRFPEHCGIGIKPCSEEGTK 207 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY--------------- 226 R++R A EYA A R V +VHK I + +G F + +L++E Sbjct: 208 RLVRAAIEYAIANDRDSVTLVHKGNIMKFTEGAFKDWGYQLAREEFGGELIDGGPWLKVK 267 Query: 227 -----PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTP 281 ++ ++ + D + +++ P+ Y V C NL GD +SD + G +G+ P Sbjct: 268 NPNTGKEIVIKDVIADAFLQQILLRPAEYD--VIACMNLNGDYISDALAA-QVGGIGIAP 324 Query: 282 SANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI----QNAV 337 ANIG + ++FEA HG+AP AGQDK NP +++LS+ MML HMG T AD I + A+ Sbjct: 325 GANIGDECALFEATHGTAPKYAGQDKVNPGSIILSAEMMLRHMGWTEAADLIVKGMEGAI 384 Query: 338 LSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + + R D A S F +A+I+ + Sbjct: 385 NAKTVTYDFERLMDGAKLLKCSEFGDAIIENM 416 >3BLX-A nrPDB Length = 349 Score = 406 bits (1043), Expect = e-114, Method: Composition-based stats. Identities = 146/343 (42%), Positives = 219/343 (63%), Gaps = 10/343 (2%) Query: 30 PNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAV 89 P G++TV+ I GDG+G EI+ SV+ IF A N+PI+WE+ ++ AV Sbjct: 11 PKKYGGRFTVTLIPGDGVGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVY---EAV 67 Query: 90 QSITKNLVALKGPLATPIGK-GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVL 148 +S+ +N + LKG TP + GH SLN+ LRK ++ANV KS++G KT ++DL++ Sbjct: 68 ESLKRNKIGLKGLWHTPADQTGHGSLNVALRKQLDIYANVALFKSLKGVKTRIPDIDLIV 127 Query: 149 IRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQ 208 IRENTEGE+SG+EH PGVV+S+K++TR +ER+ R+AF++A+ R V VHK+ I Sbjct: 128 IRENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIM 187 Query: 209 RLADGLFVNVAKELS-KEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSD 267 +L DGLF N+ E+ KEYPD+ + + ++DN+ ++ V P + V V P++YG IL + Sbjct: 188 KLGDGLFRNIITEIGQKEYPDIDVSSIIVDNASMQAVAKPHQFD--VLVTPSMYGTILGN 245 Query: 268 LNSGLSAGSLGLTPSANIGHKISIFEA-VHGSAPDIAGQDKANPTALLLSSVMMLNHMGL 326 + + L G GL AN G ++FE DI GQ+ ANPTA++LSS +MLNH+GL Sbjct: 246 IGAALIGGP-GLVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTLMLNHLGL 304 Query: 327 TNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 +A +I AV TIA G ++ T D+ G+++T+ FT +I +L Sbjct: 305 NEYATRISKAVHETIAEG-KHTTRDIGGSSSTTDFTNEIINKL 346 >5M2E-A nrPDB Length = 418 Score = 403 bits (1036), Expect = e-113, Method: Composition-based stats. Identities = 114/392 (29%), Positives = 188/392 (47%), Gaps = 63/392 (16%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDP 87 + FIEGDGIG +IS + K+ AA I W + + + T +P Sbjct: 30 IIPFIEGDGIGVDISPVMIKVVDAAVEKAYKGERKIAWMEVYAGEKATQVYDQDTWLPQE 89 Query: 88 AVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYE---NV 144 + ++ +V++KGPL TP+G G RSLN+ LR+ L+ RP + EG + + +V Sbjct: 90 TLDAVRDYVVSIKGPLTTPVGGGIRSLNVALRQQLDLYVCQRPVRWFEGVPSPVKKPGDV 149 Query: 145 DLVLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASE 181 D+V+ REN+E Y+G+E + IK ++++ ++ Sbjct: 150 DMVIFRENSEDIYAGVEWKAGSPEAEKVIKFLTEEMGVKKIRFTENCGIGIKPVSQEGTK 209 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY--------------- 226 R++R A +YA R V +VHK I + +G F + E++++ Sbjct: 210 RLVRKALQYAVDNDRSSVTLVHKGNIMKFTEGAFKDWGYEVARDEFGAELLDGGPWMQFK 269 Query: 227 -----PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTP 281 ++ ++ + D + +++ P+ Y V NL GD LSD + G +G+ P Sbjct: 270 NPKTGKNVVVKDVIADAMLQQILLRPAEYD--VIATLNLNGDYLSDALAA-EVGGIGIAP 326 Query: 282 SANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQN----AV 337 AN+ +++FEA HG+AP AGQDK NP +L+LS+ MML HMG T AD I A+ Sbjct: 327 GANLSDSVAMFEATHGTAPKYAGQDKVNPGSLILSAEMMLRHMGWTEAADLIIKGTNGAI 386 Query: 338 LSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + + R D A + S F +A+I ++ Sbjct: 387 AAKTVTYDFERLMDGATLLSCSEFGDAMIAKM 418 >3ASJ-A nrPDB Length = 334 Score = 401 bits (1030), Expect = e-112, Method: Composition-based stats. Identities = 132/336 (39%), Positives = 192/336 (57%), Gaps = 10/336 (2%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVS-PIFVNGLTTIPDPAVQSITKN 95 Y + IEGDGIG E+ + +++ A +P+E+ + F T++P+ V+ I Sbjct: 3 YRICLIEGDGIGHEVIPAARRVLEATGLPLEFVEAEAGWETFERRGTSVPEETVEKILSC 62 Query: 96 LVALKGPLATPIG--KGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENT 153 L G +P G LR+ L+ANVRPAKS + VDLV++RENT Sbjct: 63 HATLFGAATSPTRKVPGFFGAIRYLRRRLDLYANVRPAKSRP-VPGSRPGVDLVIVRENT 121 Query: 154 EGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADG 213 EG Y E V + +I++ ASER+ R A A R + + HK+ + L G Sbjct: 122 EGLYVEQERRYLD-VAIADAVISKKASERIGRAALRIAEGRPRKTLHIAHKANVLPLTQG 180 Query: 214 LFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLS 273 LF++ KE++K++P + ++ ++DN +++V P + V V NL GDILSDL +GL Sbjct: 181 LFLDTVKEVAKDFPLVNVQDIIVDNCAMQLVMRPERFD--VIVTTNLLGDILSDLAAGL- 237 Query: 274 AGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI 333 G LGL PS NIG ++FE VHGSAPDIAG+ ANPTA +LS+ MML+++G A ++ Sbjct: 238 VGGLGLAPSGNIGDTTAVFEPVHGSAPDIAGKGIANPTAAILSAAMMLDYLGEKEAAKRV 297 Query: 334 QNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + AV + GP RT DL G ATT +FTEAV++ L Sbjct: 298 EKAVDLVLERGP--RTPDLGGDATTEAFTEAVVEAL 331 >2IV0-A nrPDB Length = 412 Score = 400 bits (1029), Expect = e-112, Method: Composition-based stats. Identities = 132/410 (32%), Positives = 195/410 (47%), Gaps = 64/410 (15%) Query: 18 VKQPSIGRYTGKPNPSTGKYT------VSFIEGDGIGPEISKSVKKIFSAANVPI----- 66 VK P G K GK + + EGDGIG ++ + ++ AA I Sbjct: 6 VKPPENGE---KIRYENGKLIVPDNPIIPYFEGDGIGKDVVPAAIRVLDAAADKIGKEVV 62 Query: 67 EWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFA 126 ++ + +PD + +I + VALKGPL TP+G G+RSLN+T+R+ L+A Sbjct: 63 WFQVYAGEDAYKLYGNYLPDDTLNAIKEFRVALKGPLTTPVGGGYRSLNVTIRQVLDLYA 122 Query: 127 NVRPAKSIEGFKTTY---ENVDLVLIRENTEGEYSGIEHIVCPGVV-------------- 169 NVRP ++G + E V+ V+ RENTE Y+GIE Sbjct: 123 NVRPVYYLKGVPSPIKHPEKVNFVIFRENTEDVYAGIEWPRGSEEALKLIRFLKNEFGVT 182 Query: 170 ------QSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS 223 IK I+ A++R++R A YA R V +VHK I + +G F + E++ Sbjct: 183 IREDSGIGIKPISEFATKRLVRMAIRYAIENNRKSVTLVHKGNIMKYTEGAFRDWGYEVA 242 Query: 224 K----EY-----------------PDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYG 262 K EY + ++ + DN +++T Y V PNL G Sbjct: 243 KQEFGEYCITEDELWDKYGGKQPEGKIVVKDRIADNMFQQILTRTDEYD--VIALPNLNG 300 Query: 263 DILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLN 322 D LSD + L G LG+ P +NIG I +FE VHGSAP AGQ+K NPTA +L+ +M Sbjct: 301 DYLSDAAAAL-IGGLGIAPGSNIGDGIGVFEPVHGSAPKYAGQNKVNPTAEILTGALMFE 359 Query: 323 HMGLTNHADQIQNAVLSTIASG--PENRTGDLAGT-ATTSSFTEAVIKRL 369 ++G + ++ I+ AV TI+SG + + GT T F EAV++ L Sbjct: 360 YIGWKDASEMIKKAVEMTISSGIVTYDIHRHMGGTKVGTREFAEAVVENL 409 >5GRH-B nrPDB Length = 354 Score = 396 bits (1017), Expect = e-110, Method: Composition-based stats. Identities = 137/341 (40%), Positives = 212/341 (62%), Gaps = 10/341 (2%) Query: 32 PSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQS 91 G++TV+ I GDGIGPE+ VK +F A VP+++E VS N A+ + Sbjct: 11 KYGGRHTVTMIPGDGIGPELMLHVKSVFRHACVPVDFEEVHVSS---NADEEDIRNAIMA 67 Query: 92 ITKNLVALKGPLATP--IGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLI 149 I +N VALKG + T + H+S N LR + L+ANV KS+ G T ++++D++++ Sbjct: 68 IRRNRVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIV 127 Query: 150 RENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQR 209 RENTEGEYS +EH GVV+S+K+IT+ S R+ YAF+ A+ GR +V VHK+ I + Sbjct: 128 RENTEGEYSSLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMK 187 Query: 210 LADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLN 269 L DGLF+ +E++ YP +T E ++DN+ +++V+ P + V V PNLYG+I++++ Sbjct: 188 LGDGLFLQCCREVAARYPQITFENMIVDNTTMQLVSRPQQFD--VMVMPNLYGNIVNNVC 245 Query: 270 SGLSAGSLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTN 328 +GL G GL AN GH ++FE A + IA ++ ANPTA LL+S MML+H+ L + Sbjct: 246 AGLVGGP-GLVAGANYGHVYAVFETATRNTGKSIANKNIANPTATLLASCMMLDHLKLHS 304 Query: 329 HADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 +A I+ AVL+++ + + T D+ G TTS + VI+ + Sbjct: 305 YATSIRKAVLASMDNENMH-TPDIGGQGTTSEAIQDVIRHI 344 >6C0E-A nrPDB Length = 419 Score = 394 bits (1012), Expect = e-110, Method: Composition-based stats. Identities = 109/392 (27%), Positives = 185/392 (47%), Gaps = 63/392 (16%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDP 87 + FIEGDGIG +++ + ++ AA I W + + G +P Sbjct: 31 IIPFIEGDGIGVDVTPPMIRVVDAAVQKAYGNKRKISWMEVYAGEKATKVYGGDQWLPKE 90 Query: 88 AVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYE---NV 144 + ++ K +V++KGPL TP+G G RSLN+ +R+ L+ +RP + G + Sbjct: 91 TLDAMKKYVVSIKGPLTTPVGGGIRSLNVAIRQDMDLYVCLRPIRYFNGVPSPVREPWKT 150 Query: 145 DLVLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASE 181 D+V+ REN+E Y+GIE + +K ++R+ + Sbjct: 151 DMVIFRENSEDIYAGIEWQADTPEAKKVIQFLTKEMGVKKIRFPEHCGIGVKPVSREGTT 210 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS------KEY---PDLTLE 232 R+++ A +YA R V +VHK I + +G F + +++ KEY P + + Sbjct: 211 RLVKAAIQYAIDNDRSTVTLVHKGNIMKFTEGAFKDWGYQVARDSFGAKEYQGGPWMEFK 270 Query: 233 -----------TELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTP 281 + D + +++ P Y +V NL GD +SD + G +G+ P Sbjct: 271 NPKTGKQIIINDVIADAFLQQILLRPEDY--SVIATLNLNGDYISDALAA-QVGGIGIAP 327 Query: 282 SANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQI----QNAV 337 ANI ++++FEA HG+AP AGQ+K NP +++LS+ MML HMG AD I + A+ Sbjct: 328 GANISDQMAVFEATHGTAPKYAGQNKVNPGSIILSAEMMLRHMGWYEAADLIIRGMEGAI 387 Query: 338 LSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + + R A ++S F +A+IK + Sbjct: 388 EAKTVTYDFERGMQGATLVSSSGFADAMIKHM 419 >3U1H-A nrPDB Length = 390 Score = 389 bits (1000), Expect = e-109, Method: Composition-based stats. Identities = 121/358 (33%), Positives = 184/358 (51%), Gaps = 36/358 (10%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIFSAANVPI----EWESCDVSPIFV-NGLTTIPDPAVQ 90 K ++ + GDGIGPE+ ++ ++ A E+E + + T +P+ + Sbjct: 23 KKKIAVLPGDGIGPEVMEAAIEVLKAVAERFGHEFEFEYGLIGGAAIDEAGTPLPEETLD 82 Query: 91 SITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF------ 137 + L G + P + + L L +RK LFAN+RP K + Sbjct: 83 VCRGSDAILLGAVGGPKWDQNPSELRPEKGL-LGIRKGLDLFANLRPVKVYDSLADASPL 141 Query: 138 -KTTYENVDLVLIRENTEGEYSGIE---HIVCPGVVQSIKLITRDASERVIRYAFEYARA 193 K E VDLV++RE T G Y G + L TR+ ER+IR AFE A Sbjct: 142 KKEVIEGVDLVIVRELTGGLYFGEPSERYEEGEEAAVDTLLYTREEIERIIRKAFELALT 201 Query: 194 IGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDA 253 + +V V K+ + + L+ VA+E++KEYPD+ LE L+DN+ ++++ NP + Sbjct: 202 R-KKKVTSVDKANVLE-SSRLWREVAEEVAKEYPDVELEHMLVDNAAMQLIRNPRQFD-- 257 Query: 254 VSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG-HKISIFEAVHGSAPDIAGQDKANPTA 312 V V N++GDILSD S ++ GSLG+ PSA++ + ++E VHGSAPDIAG+ ANP A Sbjct: 258 VIVTENMFGDILSDEASMIT-GSLGMLPSASLSTDGLGLYEPVHGSAPDIAGKGIANPLA 316 Query: 313 LLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTA----TTSSFTEAV 365 +LS+ MML + GL A I+ AV +A G RT D+A +T+ T+ V Sbjct: 317 TILSAAMMLRYSFGLEEEAKAIEKAVEKVLAEG--YRTADIAKPGGKYVSTTEMTDEV 372 >2E5M-A nrPDB Length = 409 Score = 388 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 123/411 (29%), Positives = 194/411 (47%), Gaps = 68/411 (16%) Query: 19 KQPSIGRYTGKPNPSTGKYTVS------FIEGDGIGPEISKSVKKIFSAA-------NVP 65 K+P G K GK+ V +IEGDGIGPEI+ + K+ + A + Sbjct: 4 KEPEDGE---KIKFDKGKWIVPNKPVILYIEGDGIGPEITNAAIKVINKAVERAYGSSRE 60 Query: 66 IEWESCDVSPIFVN-GLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGL 124 I+W P + + K V LKGPL TPIGKG +S+N+ +R L Sbjct: 61 IKWLEVYAGEKAEKLVNDRFPKETQEMLLKYRVVLKGPLETPIGKGWKSVNVAIRLMLDL 120 Query: 125 FANVRPAKSIEGFKTTY---ENVDLVLIRENTEGEYSGIEHIVCPGVVQ----------- 170 +AN+RP K IEG ++ E VD+++ RENT+ Y GIE+ + Sbjct: 121 YANIRPVKYIEGLESPLKHPEKVDMIIFRENTDDLYRGIEYPFNSEEAKKIRDFLRKELK 180 Query: 171 ---------SIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKE 221 IK++++ ++R+ R A +YA R +V ++HK + + +G F A E Sbjct: 181 VEIEDDTGIGIKVMSKYKTQRITRLAIQYAIEHKRKKVTIMHKGNVMKYTEGAFREWAYE 240 Query: 222 LS-KEYPD-----------------LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGD 263 ++ KEY D + L + DN +++ P Y + + PN+ GD Sbjct: 241 VALKEYRDFIVTEEEINQGKPDQGKIILNDRIADNMFQQIIIRPEEYD--IILAPNVNGD 298 Query: 264 ILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNH 323 +SD L G++G+ ANIG + +FEA+HG+AP AG++ ANPT ++ + +ML Sbjct: 299 YISDAAGAL-IGNIGMLGGANIGDEGGMFEAIHGTAPKYAGKNVANPTGIIKAGELMLRW 357 Query: 324 MGLTNHADQIQNAVLSTIASGPENRTGDLA-----GTATTSSFTEAVIKRL 369 MG AD I+ A+ I + T D+A T + + +IK + Sbjct: 358 MGWNEAADLIEKAINMAIRD--KKVTQDIARFMGVKALGTKEYADELIKIM 406 >1CNZ-A nrPDB Length = 363 Score = 388 bits (996), Expect = e-108, Method: Composition-based stats. Identities = 108/360 (30%), Positives = 175/360 (48%), Gaps = 36/360 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAA----NVPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ K+ A ++ I DV I + N +P V+ Sbjct: 5 YHIAVLPGDGIGPEVMAQALKVMDAVRSRFDMRITTSHYDVGGIAIDNHGHPLPKATVEG 64 Query: 92 ITKNLVALKGPLATPIGK-------GHRSLNLTLRKTFGLFANVRPAKSIEGFK------ 138 + L G + P + R L LRK F LF+N+RPAK +G + Sbjct: 65 CEQADAILFGSVGGPKWENLPPESQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 139 --TTYENVDLVLIRENTEGEYSGI----EHIVCPGVVQSIKLITRDASERVIRYAFEYAR 192 D++ +RE T G Y G E ++ R ER+ R AFE AR Sbjct: 125 ADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESAR 184 Query: 193 AIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTD 252 R V + K+ + + + L+ + +++K YPD+ L IDN+ ++++ +PS + Sbjct: 185 KRRRK-VTSIDKANVLQ-SSILWREIVNDVAKTYPDVELAHMYIDNATMQLIKDPSQFD- 241 Query: 253 AVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH-KISIFEAVHGSAPDIAGQDKANPT 311 V +C NL+GDILSD + ++ GS+G+ PSA++ ++E GSAPDIAG++ ANP Sbjct: 242 -VLLCSNLFGDILSDECAMIT-GSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPI 299 Query: 312 ALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL---AGTATTSSFTEAVIK 367 A +LS ++L + + + A I+ A+ + G RTGDL A +T + + + Sbjct: 300 AQILSLALLLRYSLDANDAATAIEQAINRALEEGV--RTGDLARGAAAVSTDEMGDIIAR 357 >1HQS-A nrPDB Length = 423 Score = 386 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 124/405 (30%), Positives = 185/405 (45%), Gaps = 76/405 (18%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESCDVSPIFVN-GLTTIPDPAV 89 + FIEGDG GP+I + K+ AA I W+ N +P + Sbjct: 21 IIPFIEGDGTGPDIWNAASKVLEAAVEKAYKGEKKITWKEVYAGEKAYNKTGEWLPAETL 80 Query: 90 QSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVDL 146 I + +A+KGPL TP+G G RSLN+ LR+ LF +RP + G + E+ D+ Sbjct: 81 DVIREYFIAIKGPLTTPVGGGIRSLNVALRQELDLFVCLRPVRYFTGVPSPVKRPEDTDM 140 Query: 147 VLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASERV 183 V+ RENTE Y+GIE+ VQ IK ++ + + R+ Sbjct: 141 VIFRENTEDIYAGIEYAKGSEEVQKLISFLQNELNVNKIRFPETSGIGIKPVSEEGTSRL 200 Query: 184 IRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS-KEYPD-------------- 228 +R A +YA GR V +VHK I + +G F N EL+ KEY D Sbjct: 201 VRAAIDYAIEHGRKSVTLVHKGNIMKFTEGAFKNWGYELAEKEYGDKVFTWAQYDRIAEE 260 Query: 229 ------------------LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNS 270 + ++ + D + +++T P+ + V NL GD +SD + Sbjct: 261 QGKDAANKAQSEAEAAGKIIIKDSIADIFLQQILTRPNEFD--VVATMNLNGDYISDALA 318 Query: 271 GLSAGSLGLTPSANIGH--KISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTN 328 G +G+ P ANI + +IFEA HG+AP AG DK NP++++LS V++L H+G Sbjct: 319 A-QVGGIGIAPGANINYETGHAIFEATHGTAPKYAGLDKVNPSSVILSGVLLLEHLGWNE 377 Query: 329 HADQIQNAVLSTIAS----GPENRTGDLAGTATTSSFTEAVIKRL 369 AD + ++ TIAS R D A S F E +IK + Sbjct: 378 AADLVIKSMEKTIASKVVTYDFARLMDGATEVKCSEFGEELIKNM 422 >3DMS-A nrPDB Length = 427 Score = 386 bits (993), Expect = e-108, Method: Composition-based stats. Identities = 107/392 (27%), Positives = 185/392 (47%), Gaps = 63/392 (16%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESC---DVSPIFVNGLTTIPDP 87 + +IEGDG G +I+ + K+ AA I W + + +P+ Sbjct: 38 IIPYIEGDGTGFDITPVMIKVVDAAVEKAYGGKKKIHWMEIYAGEKATKVYGPDVWLPEE 97 Query: 88 AVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENV 144 +Q + + +V++KGPL TP+G G RSLN+ LR+ L+ +RP + +G + E Sbjct: 98 TLQVLKEYVVSIKGPLTTPVGGGIRSLNVALRQELDLYVCLRPIQYFKGVPSPVREPEKT 157 Query: 145 DLVLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASE 181 ++V+ REN+E Y+GIE + IK ++++ +E Sbjct: 158 NMVIFRENSEDIYAGIEWAAESEQAKKVIKFLQEEMGVKKIRFPQTSGIGIKPVSKEGTE 217 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS-KEYP------------- 227 R++R A +YA R V +VHK I + +G F + L+ KE+ Sbjct: 218 RLVRKAIQYAIDNDRKSVTLVHKGNIMKFTEGAFRDAGYALAQKEFGAELIDGGPWMKFK 277 Query: 228 ------DLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTP 281 ++ ++ + D + +++ P+ Y V NL GD +SD + G +G+ P Sbjct: 278 NPKTGNEIVVKDSIADAFLQQILLRPAEYD--VIATLNLNGDYISDALAA-QVGGIGIAP 334 Query: 282 SANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTI 341 AN+ +++FEA HG+AP AG+D NP + +LS+ MML H+G T AD I +A+ +I Sbjct: 335 GANLSDSVAMFEATHGTAPKYAGKDYVNPGSEILSAEMMLRHLGWTEAADVIISAMEKSI 394 Query: 342 ----ASGPENRTGDLAGTATTSSFTEAVIKRL 369 + R + A + S F + +I+ + Sbjct: 395 KQKRVTYDFARLMEGATQVSCSGFGQVLIENM 426 >1XAD-A nrPDB Length = 345 Score = 383 bits (984), Expect = e-107, Method: Composition-based stats. Identities = 120/353 (33%), Positives = 185/353 (52%), Gaps = 29/353 (8%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFVNG-LTTIPDPAVQS 91 V+ + GDGIGPE++++ K+ A + + + +E ++ P+P + Sbjct: 1 MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKG 60 Query: 92 ITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF------- 137 + + L G + P + + L L++RK LFAN+RP K E Sbjct: 61 VEEAEAVLLGSVGGPKWDQNPRELRPEKGL-LSIRKQLDLFANLRPVKVFESLSDASPLK 119 Query: 138 KTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRP 197 K +NVD V++RE T G Y G + + + ++ ERV R AFE AR R Sbjct: 120 KEYIDNVDFVIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RK 178 Query: 198 RVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVC 257 V+ V K+ + + + + +E+ + YPD+ LE + +D + +V +P+ + V V Sbjct: 179 HVVSVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFD--VVVT 235 Query: 258 PNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSS 317 N++GDILSDL S L GSLGL PSA++G +FE VHGSAPDIAG+ ANPTA +LS+ Sbjct: 236 GNIFGDILSDLASVLP-GSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSA 294 Query: 318 VMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 MML H GL A ++++AV + P DL G+A T +FT V++ L Sbjct: 295 AMMLEHAFGLVELARKVEDAVAKALLETPP---PDLGGSAGTEAFTATVLRHL 344 >1IDM-A nrPDB Length = 343 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 118/350 (33%), Positives = 183/350 (52%), Gaps = 25/350 (7%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFVNG-LTTIPDPAVQS 91 V+ + GDGIGPE++++ K+ A + + + +E ++ P+P + Sbjct: 1 MKVAVLPGDGIGPEVTEAALKVLRALDEAEGLGLAYEVFPFGGAAIDAFGEPFPEPTRKG 60 Query: 92 ITKNLVALKGPLATPIGKG----HRSLNLTLRKTFGLFANVRPAKSIEGFK-------TT 140 + + L G + P L+LRK+ LFAN+RPAK G + Sbjct: 61 VEEAEAVLLGSVGGPKWGTGSVRPEQGLLSLRKSQDLFANLRPAKVFPGLERLSPLKEEI 120 Query: 141 YENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVI 200 VD++++RE T G Y G + + + ++ ERV R AFE AR R V+ Sbjct: 121 ARGVDVLIVRELTGGIYFGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKR-RKHVV 179 Query: 201 VVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNL 260 V K+ + + + + +E+ + YPD+ LE + +D + +V +P+ + V V N+ Sbjct: 180 SVDKANVLEVGE-FWRKTVEEVGRGYPDVALEHQYVDAMAMHLVRSPARFD--VVVTGNI 236 Query: 261 YGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMM 320 +GDILSDL S L GSLGL PSA++G +FE VHGSAPDIAG+ ANPTA +LS+ MM Sbjct: 237 FGDILSDLASVLP-GSLGLLPSASLGRGTPVFEPVHGSAPDIAGKGIANPTAAILSAAMM 295 Query: 321 LNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 L H GL A ++++AV + P DL G+A T +FT V++ L Sbjct: 296 LEHAFGLVELARKVEDAVAKALLETPP---PDLGGSAGTEAFTATVLRHL 342 >1CM7-A nrPDB Length = 363 Score = 382 bits (981), Expect = e-106, Method: Composition-based stats. Identities = 108/360 (30%), Positives = 174/360 (48%), Gaps = 36/360 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ K+ A + I DV + N +P V+ Sbjct: 5 YHIAVLPGDGIGPEVMTQALKVLDAVRNRFAMRITTSHYDVGGAAIDNHGQPLPPATVEG 64 Query: 92 ITKNLVALKGPLATPIGK-------GHRSLNLTLRKTFGLFANVRPAKSIEGFK------ 138 + L G + P + R L LRK F LF+N+RPAK +G + Sbjct: 65 CEQADAVLFGSVGGPKWEHLPPDQQPERGALLPLRKHFKLFSNLRPAKLYQGLEAFCPLR 124 Query: 139 --TTYENVDLVLIRENTEGEYSGI----EHIVCPGVVQSIKLITRDASERVIRYAFEYAR 192 D++ +RE T G Y G E ++ R ER+ R AFE AR Sbjct: 125 ADIAANGFDILCVRELTGGIYFGQPKGREGSGQYEKAFDTEVYHRFEIERIARIAFESAR 184 Query: 193 AIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTD 252 R +V + K+ + + + L+ + E++ EYPD+ L IDN+ ++++ +PS + Sbjct: 185 KR-RHKVTSIDKANVLQ-SSILWREIVNEIATEYPDVELAHMYIDNATMQLIKDPSQFD- 241 Query: 253 AVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH-KISIFEAVHGSAPDIAGQDKANPT 311 V +C NL+GDILSD + ++ GS+G+ PSA++ ++E GSAPDIAG++ ANP Sbjct: 242 -VLLCSNLFGDILSDECAMIT-GSMGMLPSASLNEQGFGLYEPAGGSAPDIAGKNIANPI 299 Query: 312 ALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL---AGTATTSSFTEAVIK 367 A +LS ++L + + + A I+ A+ + G RTGDL A +T + + + Sbjct: 300 AQILSLALLLRYSLDADDAACAIERAINRALEEGI--RTGDLARGAAAVSTDEMGDIIAR 357 >3VMJ-A nrPDB Length = 375 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 110/361 (30%), Positives = 169/361 (46%), Gaps = 39/361 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ +K+ A + IE+ DV I + N +P+ ++ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 92 ITKNLVALKGPLATPIGK-------GHRSLNLTLRKTFGLFANVRPAKSIEGFKT----- 139 L G + P + R L LR F LF N+RPAK +G + Sbjct: 74 CEAADAILFGSVGGPKWEKLPPNEQPERGALLPLRGHFELFCNLRPAKLHDGLEHMSPLR 133 Query: 140 ---TYENVDLVLIRENTEGEYSGIE----HIVCPGVVQSIKLITRDASERVIRYAFEYAR 192 + D++ +RE T G Y G +R R+ R AFE AR Sbjct: 134 SDISARGFDVLCVRELTGGIYFGKPKGRQGEGESEEAFDTMRYSRREISRIARIAFEAAR 193 Query: 193 AIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTD 252 R +V V K+ + + L+ V +E++ ++PD+ LE IDN+ ++++ P + Sbjct: 194 GR-RKKVTSVDKANVLACSV-LWRQVVEEVAVDFPDVELEHIYIDNATMQLLRRPDEFD- 250 Query: 253 AVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH-KISIFEAVHGSAPDIAGQDKANPT 311 V +C NL+GDILSD + L+ GS+GL SA++ +FE GSAPDIAG+ ANP Sbjct: 251 -VMLCSNLFGDILSDEIAMLT-GSMGLLSSASMNSTGFGLFEPAGGSAPDIAGKGIANPI 308 Query: 312 ALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL------AGTATTSSFTEA 364 A +LS+ +ML H + A I+ AV + SG TG+L TT + Sbjct: 309 AQILSAALMLRHSLKQEEAASAIERAVTKALNSG--YLTGELLSSDQRHKAKTTVQMGDF 366 Query: 365 V 365 + Sbjct: 367 I 367 >3VML-A nrPDB Length = 375 Score = 379 bits (973), Expect = e-105, Method: Composition-based stats. Identities = 108/361 (29%), Positives = 172/361 (47%), Gaps = 39/361 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ +K+ A + IE+ DV I + N +P+ ++ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLKAVEARFGLNIEYTEYDVGGIAIDNHGCPLPEATLKG 73 Query: 92 ITKNLVALKGPLATPIGK-------GHRSLNLTLRKTFGLFANVRPAKSIEGFKT----- 139 L G + P + R L LR F LF N+RPAK G + Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 140 ---TYENVDLVLIRENTEGEYSGIE----HIVCPGVVQSIKLITRDASERVIRYAFEYAR 192 + + D++ +RE T G Y G +R R+ + AFE A+ Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKGRQGEGENEEAFDTMRYSRKEIRRIAKIAFESAQ 193 Query: 193 AIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTD 252 R +V V K+ + + L+ V +E++K+YPD+ LE IDN+ ++++ P+ + Sbjct: 194 GR-RKKVTSVDKANVLACSV-LWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFD- 250 Query: 253 AVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH-KISIFEAVHGSAPDIAGQDKANPT 311 V +C NL+GDI+SD + L+ GS+GL S ++ ++E GSAPDIAGQ ANP Sbjct: 251 -VMLCSNLFGDIVSDEIAMLT-GSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPV 308 Query: 312 ALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL------AGTATTSSFTEA 364 A +LS+ ++L H + L + A I+ AV + SG TG+L TT + Sbjct: 309 AQILSAALLLRHSLKLEDAALAIEAAVSKALNSG--YLTGELLSSDQRHKAKTTVQMGDF 366 Query: 365 V 365 + Sbjct: 367 I 367 >3VMK-A nrPDB Length = 375 Score = 378 bits (970), Expect = e-105, Method: Composition-based stats. Identities = 105/365 (28%), Positives = 176/365 (48%), Gaps = 39/365 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAA----NVPIEWESCDVSPIFV-NGLTTIPDPAVQS 91 Y ++ + GDGIGPE+ +K+ +A ++ IE+ DV + N +P+ ++ Sbjct: 14 YQIAVLAGDGIGPEVMAEARKVLAAVEKRFDLSIEYSEYDVGGAAIDNHGCPLPEATLKG 73 Query: 92 ITKNLVALKGPLATPIGK-------GHRSLNLTLRKTFGLFANVRPAKSIEGFKT----- 139 L G + P + R L LR F LF N+RPAK G + Sbjct: 74 CEAADAVLFGSVGGPKWEHLPPNDQPERGALLPLRGHFELFCNMRPAKLHPGLEHMSPLR 133 Query: 140 ---TYENVDLVLIRENTEGEYSGIE----HIVCPGVVQSIKLITRDASERVIRYAFEYAR 192 + + D++ +RE T G Y G +R R+ + AFE A+ Sbjct: 134 SDISEKGFDILCVRELTGGIYFGKPKGRQGEGENEEAFDTMRYSRKEIRRIAKIAFESAQ 193 Query: 193 AIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTD 252 R +V V K+ + + L+ V +E++K+YPD+ LE IDN+ ++++ P+ + Sbjct: 194 GR-RKKVTSVDKANVLACSV-LWREVVEEVAKDYPDVELEHIYIDNATMQLLRRPNEFD- 250 Query: 253 AVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH-KISIFEAVHGSAPDIAGQDKANPT 311 V +C NL+GDI+SD + L+ GS+GL S ++ ++E GSAPDIAGQ ANP Sbjct: 251 -VMLCSNLFGDIVSDEIAMLT-GSMGLLASISMNSQGFGMYEPAGGSAPDIAGQGIANPV 308 Query: 312 ALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL------AGTATTSSFTEA 364 A +LS+ ++L H + L + A I+ AV ++ G T +L + +TS + Sbjct: 309 AQILSAALLLRHSLKLEDAALAIEAAVSKALSDG--YLTCELLPASERSQAKSTSQMGDY 366 Query: 365 VIKRL 369 + + + Sbjct: 367 IAQAI 371 >2D4V-A nrPDB Length = 429 Score = 377 bits (968), Expect = e-105, Method: Composition-based stats. Identities = 128/407 (31%), Positives = 194/407 (47%), Gaps = 80/407 (19%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAA-------NVPIEWESCDVSPIF---VNGLTTIPDP 87 + FIEGDGIG +++ +++ + AA I W +PD Sbjct: 28 IIPFIEGDGIGCDVTPAMRSVVDAAVAKVYGGQRQIAWMELFAGQKAVQLYGEGQYLPDE 87 Query: 88 AVQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENV 144 + +I + VA+KGPL TP+G G RSLN+ +R+ L+ +RP + EG + E V Sbjct: 88 TMAAIREYKVAIKGPLETPVGGGIRSLNVAMRQDLDLYVCLRPVRYFEGTPSPMRHPEKV 147 Query: 145 DLVLIRENTEGEYSGIEHIVCPGVVQ-----------------------SIKLITRDASE 181 D+V+ REN+E Y+GIE + IK ++ + SE Sbjct: 148 DMVIFRENSEDIYAGIEWPAGSPEAEKIIRFLREEMGVTKIRFPDSSAIGIKPVSTEGSE 207 Query: 182 RVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS-KEYPD------------ 228 R+IR +YA G+P V +VHK I + +G F + L+ +E+ Sbjct: 208 RLIRRTIQYALEHGKPSVSLVHKGNIMKFTEGGFRDWGYALAEREFAGRVFTWRQKAAIS 267 Query: 229 --------------------LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDL 268 L ++ + DN + +++ P Y +V NL GD +SD Sbjct: 268 KAEGKAAGQKAEQQAIADGKLIIKDVIADNFLQQILLRPEDY--SVVATLNLNGDYVSDA 325 Query: 269 NSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTN 328 + G +G+ P AN+ +IFEA HG+APDIAGQ KANP++L+LS+VMML H+G Sbjct: 326 LAA-EVGGIGMAPGANLSDTHAIFEATHGTAPDIAGQGKANPSSLILSAVMMLEHLGWGE 384 Query: 329 HADQIQNAVLSTIASGPENRTGDLAG------TATTSSFTEAVIKRL 369 A I A+ +TIA+G TGDLA +T+ FT A+I+R Sbjct: 385 AAQAIVAAMNATIAAG--EVTGDLAALRGDVPALSTTEFTAALIRRF 429 >1VLC-A nrPDB Length = 366 Score = 376 bits (967), Expect = e-105, Method: Composition-based stats. Identities = 110/368 (29%), Positives = 167/368 (45%), Gaps = 33/368 (8%) Query: 27 TGKPNPSTGKYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDV-----SPIFVNGL 81 + K + ++ + GDGIGPE+ + K+ V Sbjct: 3 SDKIHHHHHHMKIAVLPGDGIGPEVVREALKVLEVVEKKTGKTFEKVFGHIGGDAIDRFG 62 Query: 82 TTIPDPAVQSITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSI 134 +P+ + + G + P + L LRK L+AN+RP K Sbjct: 63 EPLPEETKKICLEADAIFLGSVGGPKWDDLPPEKRPEIGGLLALRKMLNLYANIRPIKVY 122 Query: 135 EGF--------KTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRY 186 K VDLV +RE + G Y G + + R ER+ R Sbjct: 123 RSLVHVSPLKEKVIGSGVDLVTVRELSYGVYYGQPRGLDEEKGFDTMIYDRKTVERIART 182 Query: 187 AFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTN 246 AFE A R +V V K+ + + L+ V E+++EYPD+ L +DN+ ++++ Sbjct: 183 AFEIA-KNRRKKVTSVDKANVL-YSSMLWRKVVNEVAREYPDVELTHIYVDNAAMQLILK 240 Query: 247 PSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQD 306 PS + V + N++GDILSD ++ L GSLGL PSA+ G K +++E GSAPDIAG++ Sbjct: 241 PSQFD--VILTTNMFGDILSDESAALP-GSLGLLPSASFGDK-NLYEPAGGSAPDIAGKN 296 Query: 307 KANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLA----GTATTSSF 361 ANP A +LS MML H G+ A +I+ AV I G RT D+A +TS Sbjct: 297 IANPIAQILSLAMMLEHSFGMVEEARKIERAVELVIEEG--YRTRDIAEDPEKAVSTSQM 354 Query: 362 TEAVIKRL 369 + + K+L Sbjct: 355 GDLICKKL 362 >1WPW-A nrPDB Length = 336 Score = 373 bits (957), Expect = e-103, Method: Composition-based stats. Identities = 131/345 (37%), Positives = 191/345 (55%), Gaps = 23/345 (6%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSP-IFVNGLTTIPDPAVQS 91 +TV+ I+GDGIGPEI K+I + N +PIE+ + +P +++ Sbjct: 2 FTVALIQGDGIGPEIVSKSKRILAKINELYSLPIEYIEVEAGDRALARYGEALPKDSLKI 61 Query: 92 ITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRE 151 I K + LKG P+G+ + + LR+ + ++AN+RPAKSI G T Y NVD++++RE Sbjct: 62 IDKADIILKG----PVGESAADVVVKLRQIYDMYANIRPAKSIPGIDTKYGNVDILIVRE 117 Query: 152 NTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLA 211 NTE Y G EHIV GV +K+ITR ASER+ + +A R +V VHK+ + R+ Sbjct: 118 NTEDLYKGFEHIVSDGVAVGMKIITRFASERIAKVGLNFAL-RRRKKVTCVHKANVMRIT 176 Query: 212 DGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSG 271 DGLF + + K + +D + +V NP + V V N+YGDILSD S Sbjct: 177 DGLFAEACRSVLK--GKVEYSEMYVDAAAANLVRNPQMFD--VIVTENVYGDILSDEASQ 232 Query: 272 LSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHAD 331 + AGSLG+ PSANIG K ++FE VHG+A DIAG++ NPTA LLS MM M ++ D Sbjct: 233 I-AGSLGIAPSANIGDKKALFEPVHGAAFDIAGKNIGNPTAFLLSVSMMYERMYELSNDD 291 Query: 332 Q-------IQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + ++NA+ + T D+ G ATT + +L Sbjct: 292 RYIKASRALENAIYLVYKE-RKALTPDVGGNATTDDLINEIYNKL 335 >4Y1P-A nrPDB Length = 337 Score = 372 bits (956), Expect = e-103, Method: Composition-based stats. Identities = 130/345 (37%), Positives = 197/345 (57%), Gaps = 23/345 (6%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFVNG-LTTIPDPAVQS 91 + V+ I+GDGIGPE+ K I + N +PIE+ + N +P +++ Sbjct: 3 FVVALIQGDGIGPEVVSKSKTILARLNEKFSLPIEYIEVEAGDTTKNKFGDALPKDSLRV 62 Query: 92 ITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRE 151 I K + LKG P+G+ + + LR + L+AN+RPAKS+ G + + +VD++++RE Sbjct: 63 IEKADMILKG----PVGETAADVVVKLRLMYDLYANLRPAKSLPGLENKFGDVDILVVRE 118 Query: 152 NTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLA 211 NTE Y G+EH++ GV IK+ITR AS R+ + A A + +V+ VHKS + R+ Sbjct: 119 NTEDLYKGLEHVISDGVTVGIKVITRAASTRIAQVALNQAL-RRKKKVVCVHKSNVMRIT 177 Query: 212 DGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSG 271 DGLF + + K + +D + +V NP A+ V V N YGDILSD +G Sbjct: 178 DGLFAESCRNVLK--GKVEYSEMYVDAAAANLVRNPQAFD--VIVTENTYGDILSDE-AG 232 Query: 272 LSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGL----- 326 AGSLG++PSANIG + S+FE VHG+A DIAG++ ANPTA LLS MML+ M Sbjct: 233 QIAGSLGISPSANIGDRKSLFEPVHGAAFDIAGKNIANPTAFLLSVGMMLDRMQELSGDI 292 Query: 327 --TNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 N A +++A+ S + G + T D+ G++TT A+ ++ Sbjct: 293 RYNNAAKSLRDAIYSVYSEG-KYLTPDVGGSSTTDEMISAIRSKI 336 >1V5B-A nrPDB Length = 366 Score = 365 bits (937), Expect = e-101, Method: Composition-based stats. Identities = 115/362 (31%), Positives = 181/362 (50%), Gaps = 36/362 (9%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCD-----VSPIFVNGLTTIPDPAVQ 90 K ++ + GDGIGPE+ + ++ E+ T +P+ + Sbjct: 2 KMKLAVLPGDGIGPEVMDAAIRVLKTVLDNDGHEAVFENALIGGAAIDEAGTPLPEETLD 61 Query: 91 SITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF------ 137 ++ L G + P + + L L LRK GLFAN+RP K+ Sbjct: 62 ICRRSDAILLGAVGGPKWDHNPASLRPEKGL-LGLRKEMGLFANLRPVKAYATLLNASPL 120 Query: 138 -KTTYENVDLVLIRENTEGEYSGIE---HIVCPGVVQSIKLITRDASERVIRYAFEYARA 193 + ENVDLV++RE T G Y G V TR+ ER+I AF+ A+ Sbjct: 121 KRERVENVDLVIVRELTGGLYFGRPSERRGPGENEVVDTLAYTREEIERIIEKAFQLAQ- 179 Query: 194 IGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDA 253 I R ++ V K+ + + ++ +A+E +K+YPD+ L L+D++ ++++ NP + Sbjct: 180 IRRKKLASVDKANVLE-SSRMWREIAEETAKKYPDVELSHMLVDSTAMQLIANPGQFD-- 236 Query: 254 VSVCPNLYGDILSDLNSGLSAGSLGLTPSANI-GHKISIFEAVHGSAPDIAGQDKANPTA 312 V V N++GDILSDL + + GSLG+ PSA++ + ++E VHGSAPDIAGQ KANP Sbjct: 237 VIVTENMFGDILSDL-ASVITGSLGMLPSASLRSDRFGMYEPVHGSAPDIAGQGKANPLG 295 Query: 313 LLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDL----AGTATTSSFTEAVIK 367 +LS+ +ML + GL A I+ AV + G TGDL +T T+ +I+ Sbjct: 296 TVLSAALMLRYSFGLEKEAAAIEKAVDDVLQDG--YCTGDLQVANGKVVSTIELTDRLIE 353 Query: 368 RL 369 +L Sbjct: 354 KL 355 >3FMX-X nrPDB Length = 364 Score = 363 bits (931), Expect = e-100, Method: Composition-based stats. Identities = 108/359 (30%), Positives = 170/359 (47%), Gaps = 38/359 (10%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVP---------IEWESCDVSPIFVNGLTTIPDP 87 + ++ I GDGIG E+ ++ AA + EW SCD ++ +PD Sbjct: 6 FRIAAIPGDGIGLEVLPEGIRVLEAAALKHGLALEFDTFEWASCDY---YLQHGKMMPDD 62 Query: 88 AVQSITKNLVALKGPLATPIG-KGHRSLN---LTLRKTFGLFANVRPAKSIEGFKT---- 139 + + + G + P H SL L R+ F + N+RP + G Sbjct: 63 WAEQLKQYDAIYFGAVGWPDKVPDHISLWGSLLKFRREFDQYVNIRPVRLFPGVPCALAN 122 Query: 140 -TYENVDLVLIRENTEGEYSGIEHIVCPGVVQSI----KLITRDASERVIRYAFEYARAI 194 ++D V++RENTEGEYS + I+ I + TR +R+++YAF+ A Sbjct: 123 RKVGDIDFVVVRENTEGEYSSLGGIMFENTENEIVIQESIFTRRGVDRILKYAFDLAEKR 182 Query: 195 GRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAV 254 R V KS ++ + + ++ YP ++ + + ID + V P + V Sbjct: 183 ERKHVTSATKSNGMAISMPYWDKRTEAMAAHYPHVSWDKQHIDILCARFVLQPERFD--V 240 Query: 255 SVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHK---ISIFEAVHGSAPDIAGQDKANPT 311 V NL+GDILSDL AG++G+ PSAN+ + S+FE VHGSAPDI G++ ANP Sbjct: 241 VVASNLFGDILSDLGPA-CAGTIGIAPSANLNPERNFPSLFEPVHGSAPDIFGKNIANPI 299 Query: 312 ALLLSSVMMLNHMGLTN-----HADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAV 365 A++ S +ML +G + D + NA+ IA G + T D+ GT +T A+ Sbjct: 300 AMIWSGALMLEFLGQGDERYQRAHDDMLNAIERVIADG--SVTPDMGGTLSTQQVGAAI 356 >3TY3-A nrPDB Length = 366 Score = 361 bits (927), Expect = e-100, Method: Composition-based stats. Identities = 123/364 (33%), Positives = 189/364 (51%), Gaps = 33/364 (9%) Query: 33 STGKYTVSFIEGDGIGPEISKSVKKIFS----AANVPIEWESCDVS-PIFVNGLTTIPDP 87 +T + + I DGIG E+ + +++ + ++ D F +P+ Sbjct: 7 ATRRIVLGLIPADGIGKEVVPAARRLMENLPAKHKLKFDFIDLDAGWGTFERTGKALPER 66 Query: 88 AVQSIT-KNLVALKGPLATPIGK--GHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENV 144 V+ + + AL G + +P K G+ S + LRK GL+ANVRP KS++G K + V Sbjct: 67 TVERLKTECNAALFGAVQSPTHKVAGYSSPIVALRKKMGLYANVRPVKSLDGAKG--KPV 124 Query: 145 DLVLIRENTEGEYSGIEHIV----CPGVVQSIKLITRDASERVIRYAFEYARAI------ 194 DLV++RENTE Y E +V V ++I+ I+ +AS ++ + AFE A++ Sbjct: 125 DLVIVRENTECLYVKEERMVQNTPGKRVAEAIRRISEEASTKIGKMAFEIAKSRQKIRES 184 Query: 195 ------GRPRVIVVHKSTIQRLADGLFVNVAK---ELSKEYPDLTLETELIDNSVLKVVT 245 +P V ++HKS + + DGLF + L Y + ++ +++D+ V ++ Sbjct: 185 GTYSIHKKPLVTIIHKSNVMSVTDGLFRESCRHAQSLDPSYASINVDEQIVDSMVYRLFR 244 Query: 246 NPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQ 305 P + V V PNLYGDILSD + L GSLGL PSAN+G + E VHGSAPDIAG+ Sbjct: 245 EPECFD--VVVAPNLYGDILSDGAASL-IGSLGLVPSANVGDNFVMSEPVHGSAPDIAGR 301 Query: 306 DKANPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAV 365 ANP A S +ML MG + A I AV + G + T DL G + T+ T+AV Sbjct: 302 GIANPVATFRSVALMLEFMGHQDAAADIYTAVDKVLTEG-KVLTPDLGGKSGTNEITDAV 360 Query: 366 IKRL 369 + + Sbjct: 361 LANI 364 >3UDO-A nrPDB Length = 361 Score = 360 bits (925), Expect = e-100, Method: Composition-based stats. Identities = 99/354 (27%), Positives = 167/354 (47%), Gaps = 26/354 (7%) Query: 37 YTVSFIEGDGIGPEISKSVKKIF----SAANVPIEWESCDVSPIFVNG-LTTIPDPAVQS 91 Y V+ + GDGIGP + K KI N E + ++ + D ++ Sbjct: 7 YKVAVLAGDGIGPLVMKEALKILTFIAQKYNFSFELNEAKIGGASIDAYGVALSDETLKL 66 Query: 92 ITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF------- 137 ++ L G + P + R+ L LRK F LFAN+RP K E Sbjct: 67 CEQSDAILFGSVGGPKWDNLPIDQRPERASLLPLRKHFNLFANLRPCKIYESLTHASPLK 126 Query: 138 -KTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGR 196 + + VD++ +RE T G Y G + + ++ T+ ER+ R AFE AR I + Sbjct: 127 NEIIQKGVDILCVRELTGGIYFGKQD-LGKESAYDTEIYTKKEIERIARIAFESAR-IRK 184 Query: 197 PRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSV 256 +V ++ K+ + + L+ V ++K+Y D+ LE +DN+ +++V NPS + V + Sbjct: 185 KKVHLIDKANVLA-SSILWREVVANVAKDYQDINLEYMYVDNAAMQIVKNPSIFD--VML 241 Query: 257 CPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLS 316 C NL+GDILSD + ++ L+ ++ ++E GSAPDIA + ANP A +LS Sbjct: 242 CSNLFGDILSDELAAINGSLGLLSSASLNDKGFGLYEPAGGSAPDIAHLNIANPIAQILS 301 Query: 317 SVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 + +ML + A I+NA+ +A G + + T + +++ L Sbjct: 302 AALMLKYSFKEEQAAQDIENAISLALAQGKMTKDLNAKSYLNTDEMGDCILEIL 355 >1A05-A nrPDB Length = 358 Score = 360 bits (924), Expect = e-100, Method: Composition-based stats. Identities = 102/360 (28%), Positives = 167/360 (46%), Gaps = 34/360 (9%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVPIEW-----ESCDVSPIFVNGLTTIPDPAVQS 91 ++ GDGIGPEI + +++ A + E +P ++Q Sbjct: 2 KKIAIFAGDGIGPEIVAAARQVLDAVDQAAHLGLRCTEGLVGGAALDASDDPLPAASLQL 61 Query: 92 ITKNLVALKGPLATPIGKGH------RSLNLTLRKTFGLFANVRPAKSIEGF-------K 138 + G + P + L LRK L+AN+RPA+ Sbjct: 62 AMAADAVILGAVGGPRWDAYPPAKRPEQGLLRLRKGLDLYANLRPAQIFPQLLDASPLRP 121 Query: 139 TTYENVDLVLIRENTEGEYSGIEHIV----CPGVVQSIKLITRDASERVIRYAFEYARAI 194 +VD++++RE T Y G + + + D R+ AF A+ Sbjct: 122 ELVRDVDILVVRELTGDIYFGQPRGLEVIDGKRRGFNTMVYDEDEIRRIAHVAFRAAQGR 181 Query: 195 GRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAV 254 R ++ V K+ + L+ V E++++YPD+ L +DN+ ++++ P+ + V Sbjct: 182 -RKQLCSVDKANVLETT-RLWREVVTEVARDYPDVRLSHMYVDNAAMQLIRAPAQFD--V 237 Query: 255 SVCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALL 314 + N++GDILSD S L+ GS+G+ PSA++G +++E +HGSAPDIAGQDKANP A + Sbjct: 238 LLTGNMFGDILSDEASQLT-GSIGMLPSASLGEGRAMYEPIHGSAPDIAGQDKANPLATI 296 Query: 315 LSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTAT----TSSFTEAVIKRL 369 LS MML H + A +++ AV + G RT D+A T T + AV+ L Sbjct: 297 LSVAMMLRHSLNAEPWAQRVEAAVQRVLDQGL--RTADIAAPGTPVIGTKAMGAAVVNAL 354 >1XGV-A nrPDB Length = 435 Score = 358 bits (920), Expect = 2e-99, Method: Composition-based stats. Identities = 116/390 (29%), Positives = 184/390 (47%), Gaps = 63/390 (16%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAANVPI--------EWESCDVSPIFVNGLTTIPDPAV 89 V+FI GDG+GPE+ +S K+ AA + WE +P + Sbjct: 37 VVAFIRGDGVGPEVVESALKVVDAAVKKVYGGSRRIVWWELLAGHLAREKCGELLPKATL 96 Query: 90 QSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSI-EGFKTTYEN-VDLV 147 + I VALKGPL TP+G G+RSLN+ +R+ L+AN+RP + + Y + VD+V Sbjct: 97 EGIRLARVALKGPLETPVGTGYRSLNVAIRQALDLYANIRPVRYYGQPAPHKYADRVDMV 156 Query: 148 LIRENTEGEYSGIEHI--------------------VCPGVVQSIKLITRDASERVIRYA 187 + RENTE Y+GIE + +K I+R A+ R++ A Sbjct: 157 IFRENTEDVYAGIEWPHDSPEAARIRRFLAEEFGISIREDAGIGVKPISRFATRRLMERA 216 Query: 188 FEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS---------------KEYPDLT-- 230 E+A G V ++HK I + +G F+ A E++ ++Y + Sbjct: 217 LEWALRNGNTVVTIMHKGNIMKYTEGAFMRWAYEVALEKFREHVVTEQEVQEKYGGVRPE 276 Query: 231 ----LETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG 286 + + DN + +++T P + V V PNL GD +SD S L G +G+ N+G Sbjct: 277 GKILVNDRIADNMLQQIITRP--WDYQVIVAPNLNGDYISDAASAL-VGGIGMAAGMNMG 333 Query: 287 HKISIFEAVHGSAPDIAGQDKANPTALLLSSVMML-NHMGLTNHADQIQNAVLSTIASGP 345 I++ E VHG+AP AG+D NP+A +LS+ +++ MG ++ A+ + S Sbjct: 334 DGIAVAEPVHGTAPKYAGKDLINPSAEILSASLLIGEFMGWREVKSIVEYAIRKAVQS-- 391 Query: 346 ENRTGDLA------GTATTSSFTEAVIKRL 369 + T DLA TS +TE +I + Sbjct: 392 KKVTQDLARHMPGVQPLRTSEYTETLIAYI 421 >4IWH-A nrPDB Length = 363 Score = 356 bits (915), Expect = 7e-99, Method: Composition-based stats. Identities = 103/362 (28%), Positives = 165/362 (45%), Gaps = 36/362 (9%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPI-FVNGLTTIPDPAVQSITKN 95 ++ + GDGIGPEI K+ +A + E E V + +PD + + Sbjct: 9 MKIAVLPGDGIGPEIVNEAVKVLNALDEKFELEHAPVGGAGYEASGHPLPDATLALAKEA 68 Query: 96 LVALKGPLA-TPIGKGHRSL-----NLTLRKTFGLFANVRPAKSIEGF-------KTTYE 142 L G + R+L L LRK LFAN RPA Sbjct: 69 DAILFGAVGDWKYDSLERALRPEQAILGLRKHLELFANFRPAICYPQLVDASPLKPELVA 128 Query: 143 NVDLVLIRENTEGEYSGIEHIV---------CPGVVQSIKLITRDASERVIRYAFEYARA 193 +D++++RE Y G V + R+ AF+ A+ Sbjct: 129 GLDILIVRELNGDIYFGQPRGVRAAPDGPFAGEREGFDTMRYSEPEVRRIAHVAFQAAQK 188 Query: 194 IGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDA 253 +++ V KS + + + +V ++SKEY D+ L +DN+ +++ P + Sbjct: 189 RA-KKLLSVDKSNVLETSQ-FWRDVMIDVSKEYADVELSHMYVDNAAMQLAKAPKQFD-- 244 Query: 254 VSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG-HKISIFEAVHGSAPDIAGQDKANPTA 312 V V N++GDILSD S L+ GS+G+ PSA++ + ++E HGSAPDIAG+ ANP A Sbjct: 245 VIVTGNMFGDILSDEASMLT-GSIGMLPSASLDKNNKGLYEPSHGSAPDIAGKGIANPLA 303 Query: 313 LLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTAT----TSSFTEAVIK 367 +LS+ M+L + + AD+I+ AV + + G RTGD+A T++ +AV+ Sbjct: 304 TILSAAMLLRYSLNRAEQADRIERAVKTVLEQG--YRTGDIATPGCRQVGTAAMGDAVVA 361 Query: 368 RL 369 L Sbjct: 362 AL 363 >5HN5-A nrPDB Length = 353 Score = 351 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 122/332 (36%), Positives = 185/332 (55%), Gaps = 19/332 (5%) Query: 37 YTVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVS-PIFVNGLTTIPDPAVQSITKN 95 Y V+ I GDGIGPE+ ++ A + +E + +F + I + ++ I ++ Sbjct: 2 YRVAVIPGDGIGPEVIDGAVRVLKAVTGRVRFEYYEGGVDVFQECGSPIREEDLEEIRRS 61 Query: 96 LVALKGPLATPIG-KGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTE 154 L G TP G+RSL LTLRK GL+AN+R I +T E +V++REN+E Sbjct: 62 DAVLFGATTTPFDLPGYRSLILTLRKELGLYANLR---IIPDLRTGRE---IVIVRENSE 115 Query: 155 GEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGL 214 G Y GI +V G ++LITR+ +ER+ R+A E A+A G + VHK+ + D Sbjct: 116 GLYFGIGAVVN-GRAVDVRLITREGAERIARFAVEQAKARG-SFITFVHKANVL-TGDKF 172 Query: 215 FVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSA 274 F + +E++ E + + +ID+ +K+V NP + V + NL+GDILSDL + + A Sbjct: 173 FRRIVREVAGE-EGVEVRDAIIDSFTIKLVRNP--WEHGVILSENLFGDILSDL-ATVHA 228 Query: 275 GSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNHADQIQ 334 GS+G+ PS N G I++FE VHGSAPDIAG+ ANP +LS M+L+++GL I+ Sbjct: 229 GSIGIVPSGNYGDGIALFEPVHGSAPDIAGKGIANPIGAILSGAMLLDYLGLDG--SLIR 286 Query: 335 NAVLSTIASGPENRTGDLAGTATTSSFTEAVI 366 AV + +G T D+ G A T +I Sbjct: 287 AAVRGYVVNG--ELTPDMGGRARTEDVVRGII 316 >5J32-A nrPDB Length = 403 Score = 351 bits (902), Expect = 2e-97, Method: Composition-based stats. Identities = 109/369 (29%), Positives = 179/369 (48%), Gaps = 38/369 (10%) Query: 31 NPSTGKYTVSFIEGDGIGPEISKSVKKIFSAAN----VPIEWESCDVSPIFVN-GLTTIP 85 +YT++ + GDGIGPE+ K + A V + + ++ +P Sbjct: 35 EFGKKRYTITLLPGDGIGPEVVSIAKNVLQQAGSLEGVEFNFREMPIGGAALDLVGVPLP 94 Query: 86 DPAVQSITKNLVALKGPLATPIG-------KGHRSLNLTLRKTFGLFANVRPAKSIEGF- 137 + + + ++ L G + + + L L +R +FAN+RPA + Sbjct: 95 EETISAAKESDAVLLGAIGGYKWDNNEKHLRPEKGL-LQIRAALKVFANLRPATVLPQLV 153 Query: 138 ------KTTYENVDLVLIRENTEGEYSGIEHIV-----CPGVVQSIKLITRDASERVIRY 186 + E VDL+++RE T G Y G + V + ++ +R+ R Sbjct: 154 DASTLKREVAEGVDLMVVRELTGGIYFGEPRGIKTNENGEEVGFNTEVYAAHEIDRIARV 213 Query: 187 AFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTN 246 AFE AR R ++ V K+ + A L+ L+ EYPD+ L +DN+ +++V + Sbjct: 214 AFETARKR-RGKLCSVDKANVLE-ASILWRKRVTALASEYPDVELSHMYVDNAAMQLVRD 271 Query: 247 PSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIGH-KISIFEAVHGSAPDIAGQ 305 P + V N++GDILSD S ++ GS+G+ PSA++ +FE +HGSAPDIAGQ Sbjct: 272 PKQFDT--IVTNNIFGDILSDEASMIT-GSIGMLPSASLSDSGPGLFEPIHGSAPDIAGQ 328 Query: 306 DKANPTALLLSSVMMLNH-MGLTNHADQIQNAVLSTIASGPENRTGDLAGTAT----TSS 360 DKANP A +LS+ M+L + +G A +I++AVL + +G RTGD+ T Sbjct: 329 DKANPLATILSAAMLLKYGLGEEKAAKRIEDAVLVALNNG--FRTGDIYSAGTKLVGCKE 386 Query: 361 FTEAVIKRL 369 E V+K + Sbjct: 387 MGEEVLKSV 395 >2G4O-A nrPDB Length = 337 Score = 326 bits (835), Expect = 1e-89, Method: Composition-based stats. Identities = 108/346 (31%), Positives = 171/346 (49%), Gaps = 25/346 (7%) Query: 38 TVSFIEGDGIGPEISKSVKKIFSAANVPIEWESCDVSPI-FVNGLTTIPDPAVQSITKNL 96 ++ I GDGIGPE++ K+ A ++ S D+ F +PD V + + Sbjct: 3 KLAIIAGDGIGPEVTAEAVKVLDAVVPGVQKTSYDLGARRFHATGEVLPDSVVAELRNHD 62 Query: 97 VALKGPLA---TPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY---ENVDLVLIR 150 L G + P G R L L LR N+RPA+ G + +D V++R Sbjct: 63 AILLGAIGDPSVPSGVLERGLLLRLRFELDHHINLRPARLYPGVASPLSGNPGIDFVVVR 122 Query: 151 ENTEGEYSGIEHIVCPG----VVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKST 206 E TEG Y+G + G V + + T RV+ AFE AR R + +VHK+ Sbjct: 123 EGTEGPYTGNGGAIRVGTPNEVATEVSVNTAFGVRRVVADAFERAR-RRRKHLTLVHKTN 181 Query: 207 IQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILS 266 + A GL++ E+ + YPD+ + + +D + + ++T+P + V V NL+GDI++ Sbjct: 182 VLTFAGGLWLRTVDEVGECYPDVEVAYQHVDAATIHMITDPGRFD--VIVTDNLFGDIIT 239 Query: 267 DLNSGLSAGSLGLTPSANIGHKIS---IFEAVHGSAPDIAGQDKANPTALLLSSVMMLNH 323 DL + + G +GL S NI + +FE VHGSAPDIAGQ A+PTA ++S ++L+H Sbjct: 240 DLAAAVC-GGIGLAASGNIDATRANPSMFEPVHGSAPDIAGQGIADPTAAIMSVALLLSH 298 Query: 324 MGLTNHADQIQNAVLSTIASGPENRTGDLAGTATTSSFTEAVIKRL 369 +G + A ++ AV + +A+ R TS E + L Sbjct: 299 LGEHDAAARVDRAVEAHLATRGSER-------LATSDVGERIAAAL 337 >1ZOR-A nrPDB Length = 399 Score = 83.5 bits (205), Expect = 1e-16, Method: Composition-based stats. Identities = 72/367 (19%), Positives = 133/367 (36%), Gaps = 67/367 (18%) Query: 64 VPIEWESCDVS-PIFVNGLTTIPDPAVQSITKNLVALKGPLATP---------IGKGHRS 113 + I+ D+ I A ++I K V +K TP + K +S Sbjct: 35 LDIQLVYFDLGIKKRDETDDQITIEAAKAIKKYGVGVKCATITPDAERVKEYNLKKAWKS 94 Query: 114 LNLTLRKTFGLFANVRP--AKSIEGFKTTYENVDLVLIRENTEGEYSGIEHIVCPGVVQS 171 N T+R +P K++ ++ +++ R Y+ +E V G + Sbjct: 95 PNATIRAYLDGTVFRKPIMVKNVPPLVKRWKK-PIIIGRHAYGDIYNAVEAKV-EGPAEV 152 Query: 172 IKLITRDASERVIRYAFE-----YARAIGRPRVIV------------------VHKSTIQ 208 ++ ++ ++ + FE A + K TI Sbjct: 153 ELVVRNKENKTLLVHKFEGNGVVMAMHNLEKSIRSFAQSCINYAISEKVDIWFATKDTIS 212 Query: 209 RLADGLFVNVA-KELSK-----EYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYG 262 ++ F ++ +E+ K E + LID++ +++ + + C N G Sbjct: 213 KVYHAYFKDIFQEEVDKRKEELEKAGVNYRYMLIDDAAAQILRSEG---GMLWACMNYEG 269 Query: 263 DILSDLNSGLSAGSLGLTPSANIG-HKISIFEAVHGSAPD-----IAG-QDKANPTALLL 315 DI+SD+ + GSLGL S + + FEA HG+ + G + NPTA + Sbjct: 270 DIMSDMIAS-GFGSLGLMTSVLVSPDGVYEFEAAHGTVRRHYYRYLKGEKTSTNPTASIF 328 Query: 316 SSVMMLNHMGLT-------NHADQIQNAVLSTIASGPENRT------GDLAGTATTSSFT 362 + + G AD+++ AV++TI SG + + T F Sbjct: 329 AWTGAIRKRGELDGTPEVCEFADKLEKAVINTIESGVITKDLQPFTEPPIDKYVTLEEFI 388 Query: 363 EAVIKRL 369 + V K L Sbjct: 389 DEVKKNL 395 >2QFY-A nrPDB Length = 427 Score = 70.7 bits (172), Expect = 9e-13, Method: Composition-based stats. Identities = 83/419 (19%), Positives = 144/419 (34%), Gaps = 96/419 (22%) Query: 32 PSTGKYTVSFIEGDGIGPEISKSVKKIF-SAANVPIEWESCDVSPIFVN--------GLT 82 S K +E DG + +I + DV + + Sbjct: 16 FSKIKVKQPVVELDG------DEMTRIIWDKIKKKLILPYLDVDLKYYDLSVESRDATSD 69 Query: 83 TIPDPAVQSITKNLVALKGPLATP---------IGKGHRSLNLTLRKTFGLFANVRPAKS 133 I A ++I K V +K TP + K +S N T+R G P Sbjct: 70 KITQDAAEAIKKYGVGIKCATITPDEARVKEFNLHKMWKSPNGTIRNILGGTVFREPI-V 128 Query: 134 IEGFKTTYENVD--LVLIRENTEGEYSG----IEHIVCPGVV-----------QSIKLI- 175 I + +++ R +Y I +V Q++K+ Sbjct: 129 IPRIPRLVPRWEKPIIIGRHAHGDQYKATDTLIPGPGSLELVYKPSDPTTAQPQTLKVYD 188 Query: 176 ------------TRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS 223 T ++ E +F+ A + + + K+TI + DG F ++ +E+ Sbjct: 189 YKGSGVAMAMYNTDESIEGFAHSSFKLAID-KKLNLFLSTKNTILKKYDGRFKDIFQEVY 247 Query: 224 K-------EYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGS 276 + E + E LID+ V +++ + + + N GD+ SD+ + GS Sbjct: 248 EAQYKSKFEQLGIHYEHRLIDDMVAQMIKSKGGF---IMALKNYDGDVQSDIVAQ-GFGS 303 Query: 277 LGLTPSANIGHKISIF--EAVHGSAPDIAGQ------DKANPTALL--LSSVMMLNHMGL 326 LGL S + F EA HG+ + N A + S ++ G Sbjct: 304 LGLMTSILVTPDGKTFESEAAHGTVTRHYRKYQKGEETSTNSIASIFAWSRGLLKR--GE 361 Query: 327 TNH-------ADQIQNAVLSTIASGPENRTGDLA---------GTATTSSFTEAVIKRL 369 ++ A+ +++A L+T+ T DLA TT F +AV KRL Sbjct: 362 LDNTPALCKFANILESATLNTVQQ-DGIMTKDLALACGNNERSAYVTTEEFLDAVEKRL 419 >5I96-A nrPDB Length = 458 Score = 66.9 bits (162), Expect = 1e-11, Method: Composition-based stats. Identities = 81/383 (21%), Positives = 135/383 (35%), Gaps = 79/383 (20%) Query: 58 IFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATP---------IG 108 I ++ +++ + D A+ + K VA+K TP + Sbjct: 71 ILPHVDIQLKYFDLGLPNRDQTDDQVTIDSAL-ATQKYSVAVKCATITPDEARVEEFKLK 129 Query: 109 KGHRSLNLTLRKTFGLFANVRPA------KSIEGFKTT-----------YENVDLVLIRE 151 K +S N T++ G P + + G+ Y+ D V R Sbjct: 130 KMWKSPNGTIQNILGGTVFREPIICKNIPRLVPGWTKPITIGRHAHGDQYKATDFVADRA 189 Query: 152 NTEGEYSG-------IEHIV--CPGVVQSIKLI-TRDASERVIRYAFEYARAIGRPRVIV 201 T E V P + + T ++ F+YA P + + Sbjct: 190 GTFKMVFTPKDGSGVKEWEVYNFPAGGVGMGMYNTDESISGFAHSCFQYAIQKKWP-LYM 248 Query: 202 VHKSTIQRLADGLFVNVAKEL-SKEYP------DLTLETELIDNSVLKVVTNPSAYTDAV 254 K+TI + DG F ++ +E+ K Y + E LID+ V +V+ + + V Sbjct: 249 STKNTILKAYDGRFKDIFQEIFDKHYKTDFDKNKIWYEHRLIDDMVAQVLKSSGGF---V 305 Query: 255 SVCPNLYGDILSDLNSGLSAGSLGLTPSANI-GHKISI-FEAVHGSAPDI-----AGQDK 307 C N GD+ SD+ + GSLGL S + +I EA HG+ G+ Sbjct: 306 WACKNYDGDVQSDILAQ-GFGSLGLMTSVLVCPDGKTIEAEAAHGTVTRHYREHQKGRPT 364 Query: 308 A-NPTALLLSSVMMLNHMGLTNH-------ADQIQNAVLSTIASGPENRTGDLAG----- 354 + NP A + + L H G + A ++ + T+ SG T DLAG Sbjct: 365 STNPIASIFAWTRGLEHRGKLDGNQDLIRFAQMLEKVCVETVESGAM--TKDLAGCIHGL 422 Query: 355 --------TATTSSFTEAVIKRL 369 T+ F + + L Sbjct: 423 SNVKLNEHFLNTTDFLDTIKSNL 445 >4AOY-A nrPDB Length = 402 Score = 62.3 bits (150), Expect = 3e-10, Method: Composition-based stats. Identities = 80/401 (19%), Positives = 138/401 (34%), Gaps = 82/401 (20%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIFSA--ANVPIEWESCDVSPIFVNGLTTIPDPAVQS-- 91 K V +E DG E+++ + ++ IE + N T + + Sbjct: 5 KMKVPLVEMDG--DEMTRIIWRLIKENLLEPYIELNTEYYDLGLENRDKTEDQVTIDAAR 62 Query: 92 -ITKNLVALKGPLATP---------IGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTY 141 I K V +K TP + K +S N T+R P + K Sbjct: 63 AIQKYGVGVKCATITPNAQRVEEYNLKKMWKSPNGTIRAILDGTVFRAPI-VVNSIKPFV 121 Query: 142 ENVD--LVLIRENTEGEYSGIEHIV--------------------------CPGVVQSIK 173 + + + R Y +E+ V PGV+ + Sbjct: 122 KGWKKPISIARHAYGDVYKNVEYYVPSAGKAELVFTSENGEVSRQTIHEFDGPGVIMGMH 181 Query: 174 LITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSK-EYPD---- 228 T + R F YA + + + K TI + D F ++ +E+ + EY + Sbjct: 182 -NTDKSIRSFARACFNYALDMNQD-LWFSTKDTISKTYDHRFKDIFQEIYENEYKEKFEA 239 Query: 229 --LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANIG 286 L LID++V +++ + V C N GD++SD+ + GSL + S + Sbjct: 240 KNLQYFYTLIDDAVARIIRSEG---GMVWACKNYDGDVMSDMVASA-FGSLAMMTSVLVS 295 Query: 287 -HKISIFEAVHGSAPDIAGQDK------ANPTALLLSSVMMLNHMG-------LTNHADQ 332 FEA HG+ + N A + + L G L + A + Sbjct: 296 PDGKYEFEAAHGTVTRHYYKHLKGEETSTNSMATIFAWTGALKKRGELDGIKELVDFATK 355 Query: 333 IQNAVLSTIASGPENRTGDLAGTA--------TTSSFTEAV 365 ++ A + TI +G T DLA + T F + + Sbjct: 356 LEQASVQTIENGVM--TKDLASLSEVPEKKIVNTEDFLKEI 394 >4HCX-A nrPDB Length = 409 Score = 61.1 bits (147), Expect = 7e-10, Method: Composition-based stats. Identities = 57/222 (25%), Positives = 93/222 (41%), Gaps = 36/222 (16%) Query: 177 RDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEY-------PDL 229 +++ R +F Y + V + K+TI + DG+F + + + +E L Sbjct: 189 KESIRDFARASFSYGL-NAKWPVYLSTKNTILKAYDGMFKDEFERVYEEEFKAQFEAAGL 247 Query: 230 TLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPSANI-GHK 288 T E LID+ V + Y V C N GD+ SD + GSLGL S + Sbjct: 248 TYEHRLIDDMVAACLKWEGGY---VWACKNYDGDVQSDTVAQ-GYGSLGLMTSVLMTADG 303 Query: 289 ISI-FEAVHGSAPDI-----AGQDKA-NPTALLLSSVMMLNHMGLTNH-------ADQIQ 334 ++ EA HG+ AG+ + NP A + + L H G + A +++ Sbjct: 304 KTVEAEAAHGTVTRHYRQYQAGKPTSTNPIASIFAWTRGLQHRGKLDGTPEVIDFAHKLE 363 Query: 335 NAVLSTIASGPENRTGDLA---GT----ATTSSFTEAVIKRL 369 + V++T+ SG T DLA G + F +A+ L Sbjct: 364 SVVIATVESGKM--TKDLAILIGPEQDWLNSEEFLDAIADNL 403 >2UXQ-A nrPDB Length = 402 Score = 57.3 bits (137), Expect = 1e-08, Method: Composition-based stats. Identities = 76/409 (18%), Positives = 132/409 (32%), Gaps = 90/409 (22%) Query: 36 KYTVSFIEGDGIGPEISKSVKKIF-----SAANVPI---EWESCDVS-PIFVNGLTTIPD 86 + +E DG + ++ +P + E D+ I Sbjct: 4 QMKTPLVELDG------DEMTRVLWPLIKDKLLLPFIDLQTEYYDLGIEERDRTNDQITI 57 Query: 87 PAVQSITKNLVALKGPLATP---------IGKGHRSLNLTLRKTFGLFANVRPA---KSI 134 A ++I K V +K TP + + +S N T+R +P Sbjct: 58 DAAEAIKKYGVGVKNATITPNQDRVEEYGLKEQWKSPNATVRAMLDGTVFRKPIMVKNIK 117 Query: 135 EGFKTTYENVDLVLIRENTEGEYSGIE--------------HIVCPGVVQSIKLITRDAS 180 ++ + +V+ R Y E Q+I + A Sbjct: 118 PSVRSWQKP--IVVGRHAYGDFYKNAEIFAEAGGKLEIVVTDKNGKETRQTIMEVDEPAI 175 Query: 181 ER-----------VIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKEL-SKEYPD 228 + R FEY+ + K TI + D F + +E+ ++EY + Sbjct: 176 VQGIHNTVASIGHFARACFEYSLDQ-KIDCWFATKDTISKQYDQRFKIIFEEIFAQEYKE 234 Query: 229 ------LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLNSGLSAGSLGLTPS 282 + LID+ V +++ + C N GD++SD+ + GSL + S Sbjct: 235 KFAAAGIEYFYTLIDDVVARMMKTEG---GMLWACKNYDGDVMSDMVASA-FGSLAMMSS 290 Query: 283 ANIGH-KISIFEAVHGSAPDIAGQDK------ANPTALLLSSVMMLNHMGLTNHA----- 330 + +EA HG+ Q NP AL+ + L G + Sbjct: 291 VLVSPYGYFEYEAAHGTVQRHYYQHLKGERTSTNPVALIYAWTGALRKRGELDGTPDLCA 350 Query: 331 --DQIQNAVLSTIASGPENRTGDLA--------GTATTSSFTEAVIKRL 369 D ++ + I SG TGDLA + F + + KRL Sbjct: 351 FCDSLEAITIECIESG--YMTGDLARICEPAAIKVLDSIEFIDELGKRL 397 >3US8-A nrPDB Length = 427 Score = 51.9 bits (123), Expect = 5e-07, Method: Composition-based stats. Identities = 62/285 (21%), Positives = 101/285 (35%), Gaps = 60/285 (21%) Query: 64 VPIEWESCDVS-PIFVNGLTTIPDPAVQSITKNLVALKGPLATPIGKG---------HRS 113 + ++ E D+ + A +I K+ V +K TP +S Sbjct: 58 LDLDLEYYDLGVENRDATDDQVTIDAANAIKKHGVGVKCATITPDEGRVEEFKLKKMWKS 117 Query: 114 LNLTLRKTFGLFANVRPA------KSIEGFKTTYENVDLVLIRENTEGEYSG-------- 159 N T+R G P + + G+ +++ R +Y Sbjct: 118 PNGTIRNILGGVIFREPIICKNVPRLVPGWTKP-----IIVGRHAFGDQYRATDFKFPGK 172 Query: 160 --------------IEHIV--CPGVVQSIKLITRDAS-ERVIRYAFEYARAIGRPRVIVV 202 IEH V PG ++ + D S R +F Y P V + Sbjct: 173 GKLSIKFVGEDGQTIEHDVYDAPGAGVALAMYNLDESITEFARASFNYGLQRKVP-VYLS 231 Query: 203 HKSTIQRLADGLFVNVA-----KELSKEYPDLTL--ETELIDNSVLKVVTNPSAYTDAVS 255 K+TI + DG F ++ +E + ++ L E LID+ V + Y V Sbjct: 232 TKNTILKAYDGRFKDIFQKVFDEEFAAQFKAEKLWYEHRLIDDMVASALKWSGGY---VW 288 Query: 256 VCPNLYGDILSDLNSGLSAGSLGLTPSANIG-HKISI-FEAVHGS 298 C N GD+ SD+ + GSLGL S + ++ EA HG+ Sbjct: 289 ACKNYDGDVQSDIVAQ-GFGSLGLMTSVLMTPDGKTVEAEAAHGT 332 >5Z16-A nrPDB Length = 751 Score = 37.2 bits (85), Expect = 0.010, Method: Composition-based stats. Identities = 27/112 (24%), Positives = 42/112 (37%), Gaps = 19/112 (16%) Query: 252 DAVSVCPNLYGDILSDLNSGLSAGS----LGLTPSANIGHKISIFE-AVHGSAPDIAGQD 306 D +SV N+ D L+DL + G+ L + P + ++E GSAP Q Sbjct: 546 DTISVTGNILRDYLTDLFPIMELGTSAKMLSIVP---LMAGGGMYETGAGGSAPKHVQQL 602 Query: 307 KA------NPTALLLSSVMMLNHMGLTNHADQIQNAVLSTIASGPENRTGDL 352 + L+ + L MG+ NA +A + TG L Sbjct: 603 VEENHLRWDSLGEFLALAVSLEEMGIKE-----NNARTKLLAKTLDEATGKL 649 >3WDK-A nrPDB Length = 261 Score = 36.8 bits (84), Expect = 0.016, Method: Composition-based stats. Identities = 40/227 (17%), Positives = 73/227 (32%), Gaps = 38/227 (16%) Query: 47 IGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATP 106 IG + ++ AA V + N +P ++ L+ L Sbjct: 47 IGERTIEPAERAMRAAVAKFLLAEHPVISVNGNVAALVPKETIELAKALNAKLEINLFYR 106 Query: 107 IGKGHRSLNLTLRK---TFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEGEYSGIEHI 163 + R++ LRK + + P K I G + VD E+ Sbjct: 107 TEERVRTIAEELRKYDPEIEILG-INPTKRIPGLEHERGKVD---------------ENG 150 Query: 164 VCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELS 223 + V + L D +E ++R V+ V + + R A + + + Sbjct: 151 IWKADVVLVPLEDGDRTEALVRMG---------KFVVTVDLNPLSRSARMADITIVDNIV 201 Query: 224 KEYPD-LTLETELIDNSVLKVVTNPSAYTDAVSVCPNLYGDILSDLN 269 + YP + L E+ D S +++ Y G LSD+ Sbjct: 202 RAYPRMVELAREMKDYSREELLKIVGEYD---------NGKTLSDVL 239 >4MB2-A nrPDB Length = 261 Score = 36.1 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 19/102 (18%), Positives = 33/102 (32%), Gaps = 4/102 (3%) Query: 47 IGPEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATP 106 IG + ++ AA + V + N +P ++ L+ L Sbjct: 47 IGERTIEPAERAMRAAVAKLLLAENPVVSVNGNVAALVPKETIELARALNAKLEINLFYR 106 Query: 107 IGKGHRSLNLTLRK---TFGLFANVRPAKSIEGFKTTYENVD 145 +++ LRK L + P K I G + VD Sbjct: 107 TEDRVKAIAEELRKYDPEIELLG-INPTKRIPGLEHERGKVD 147 >1J1W-A nrPDB Length = 741 Score = 36.1 bits (82), Expect = 0.023, Method: Composition-based stats. Identities = 21/82 (25%), Positives = 31/82 (37%), Gaps = 8/82 (9%) Query: 252 DAVSVCPNLYGDILSDLNSGLSAG-SLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKA- 308 D +SV N+ D L+DL + G S + + +FE GSAP Q Sbjct: 537 DTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVPLMSGGGLFETGAGGSAPKHVQQFLEE 596 Query: 309 -----NPTALLLSSVMMLNHMG 325 + L+ L H+G Sbjct: 597 GYLRWDSLGEFLALAASLEHLG 618 >4ZDA-A nrPDB Length = 767 Score = 34.1 bits (77), Expect = 0.096, Method: Composition-based stats. Identities = 26/123 (21%), Positives = 41/123 (33%), Gaps = 17/123 (13%) Query: 252 DAVSVCPNLYGDILSDLNSGLSAG-SLGLTPSANIGHKISIFE-AVHGSAPDIAGQDKA- 308 D ++ N+ D L+DL L G S + + ++E GSAP Q Sbjct: 540 DTIAATGNILRDYLTDLFPILELGTSAKMLSIVPLMAGGGLYETGAGGSAPKHVHQLVEE 599 Query: 309 -----NPTALLLSSVMMLNHMGL---TNHADQIQNAVLSTI------ASGPENRTGDLAG 354 + L+ L MG A + A+ + P RTG+L Sbjct: 600 NHLRWDSLGEFLALGASLEDMGNKTGNEKAKVLAKALDTATGKLLEENKSPSRRTGELDN 659 Query: 355 TAT 357 + Sbjct: 660 RGS 662 >4YYC-A nrPDB Length = 525 Score = 33.4 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 24/128 (18%), Positives = 46/128 (35%), Gaps = 12/128 (9%) Query: 196 RPRVIVVHKSTIQRLADGLFVNVAK-ELSKEYPDLTLETE-LIDNSVLKVVTNPSAYTDA 253 R V + + + + G ++K + D+ D + VT P D Sbjct: 162 RNFVKLAYMAPSMHSSGGTVCEPVDIAVNKRHLDMVYSHIRYSDKPFMGSVTAPERAEDT 221 Query: 254 VSVCPNLYG-DILSDLNSGLSAGSLGLTPSANIGHKISIFEAVHGSAPDIAGQDKANPTA 312 V++ L+G D + + L+ N + E + G+A A ++A + Sbjct: 222 VAMAKILFGDDFVENNAVTLNL--------INANSPMVFDETMLGAAKVYARHNQACVVS 273 Query: 313 -LLLSSVM 319 +LS M Sbjct: 274 PFILSGAM 281 >6G3U-A nrPDB Length = 737 Score = 33.4 bits (75), Expect = 0.17, Method: Composition-based stats. Identities = 16/55 (29%), Positives = 25/55 (45%), Gaps = 8/55 (14%) Query: 252 DAVSVCPNLYGDILSDLNSGLSAGS----LGLTPSANIGHKISIFE-AVHGSAPD 301 D +SV N+ D L+DL + G+ L + P + ++E GSAP Sbjct: 533 DTISVTGNVLRDYLTDLFPIMELGTSAKMLSIVP---LMAGGGMYETGAGGSAPK 584 >5KVU-A nrPDB Length = 745 Score = 33.4 bits (75), Expect = 0.18, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 22/52 (42%), Gaps = 2/52 (3%) Query: 252 DAVSVCPNLYGDILSDLNSGLSAG-SLGLTPSANIGHKISIFE-AVHGSAPD 301 D ++ N+ D L+DL L G S + + ++E GSAP Sbjct: 540 DTIAATGNILRDYLTDLFPILELGTSAKMLSVVPLMAGGGMYETGAGGSAPK 591 >4JQP-A nrPDB Length = 342 Score = 31.5 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 12/40 (30%), Positives = 20/40 (50%), Gaps = 2/40 (5%) Query: 277 LGLTPSANIGHKISIFEAV--HGSAPDIAGQDKANPTALL 314 LGL N+ + + HG+A DIAG+ + ++L Sbjct: 290 LGLEAGVNVTVGLEVIRTSVDHGTAFDIAGKGVVDEGSML 329 >1YE8-A nrPDB Length = 178 Score = 31.1 bits (69), Expect = 0.77, Method: Composition-based stats. Identities = 18/93 (19%), Positives = 38/93 (40%), Gaps = 4/93 (4%) Query: 183 VIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDLTLETELIDNSVLK 242 ++ A+ A+ R VI++ + L F ++ +++ + P++ + + V Sbjct: 87 ILERAYREAKKDRRK-VIIIDEIGKMELFSKKFRDLVRQIMHD-PNVNVVATIPIRDVHP 144 Query: 243 VVTNPSAYTDAVS--VCPNLYGDILSDLNSGLS 273 +V AV + P IL D+ S L Sbjct: 145 LVKEIRRLPGAVLIELTPENRDVILEDILSLLE 177 >4A8J-A nrPDB Length = 361 Score = 31.1 bits (69), Expect = 0.91, Method: Composition-based stats. Identities = 22/105 (20%), Positives = 36/105 (34%), Gaps = 20/105 (19%) Query: 96 LVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVLIRENTEG 155 V L ++ I L + LR F N+ P E + + E Sbjct: 259 RVVLFASISIDIITPP--LLVLLRNMFDSVINLEPFN--------QEMTEFL------ER 302 Query: 156 EYSGIEHIVCPGVVQSIK--LITRDASERVIRYAFEYARAIGRPR 198 Y + G+V +K + T RV++ E+A GR + Sbjct: 303 VYKSQPGKIQHGLVHILKLPVFTDRGEMRVLKS--EWAFKNGRKK 345 >4V6W-CM nrPDB Length = 166 Score = 30.7 bits (68), Expect = 0.94, Method: Composition-based stats. Identities = 23/114 (20%), Positives = 39/114 (34%), Gaps = 15/114 (13%) Query: 89 VQSITKNLVALKGPLATPIGKGHRSLNLTLRKTFGLFANVRPAKSIEGFKTTYENVDLVL 148 V I +N V + GPL + +R NL L K F P + + + DL Sbjct: 28 VDVIDQNRVLVDGPLTGVPRQEYRLNNLHLTKYRIKFPYTAPTRI---VRKAWTESDL-- 82 Query: 149 IRENTEGEYSGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRVIVV 202 + V P V++ + R + R+ YA+ + + Sbjct: 83 ----------KAQWKVSPWSVKAQNICKRSSLNDFDRFKLRYAKRQRNKLLTIA 126 >1F1E-A nrPDB Length = 154 Score = 30.3 bits (67), Expect = 1.3, Method: Composition-based stats. Identities = 17/42 (40%), Positives = 20/42 (47%), Gaps = 1/42 (2%) Query: 158 SGIEHIVCPGVVQSIKLITRDASERVIRYAFEYARAIGRPRV 199 +GIE V KLI R A+E + A EYA GR V Sbjct: 95 AGIERASSDAVDLYNKLICR-ATEELGEKAAEYADEDGRKTV 135 >5NAV-A nrPDB Length = 477 Score = 30.3 bits (67), Expect = 1.5, Method: Composition-based stats. Identities = 16/51 (31%), Positives = 17/51 (33%), Gaps = 2/51 (3%) Query: 245 TNPSAYTDAVS--VCPNLYGDILSDLNSGLSAGSLGLTPSANIGHKISIFE 293 T P + V N Y D DL AG GL S I FE Sbjct: 53 TEPEQFDAGVGPDTASNFYNDYDHDLALMAQAGVQGLRTSIQWTRLIDDFE 103 >2F6U-A nrPDB Length = 234 Score = 29.9 bits (66), Expect = 1.7, Method: Composition-based stats. Identities = 11/60 (18%), Positives = 19/60 (31%), Gaps = 12/60 (20%) Query: 49 PEISKSVKKIFSAANVPIEWESCDVSPIFVNGLTTIPDPAVQSITKNLVALKGPLATPIG 108 PE+ VKK+ A + F G + A + + + G + G Sbjct: 178 PELVAEVKKVLDKARL------------FYGGGIDSREKAREMLRYADTIIVGNVIYEKG 225 >4ATY-A nrPDB Length = 349 Score = 29.5 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 36/158 (22%), Positives = 65/158 (41%), Gaps = 22/158 (13%) Query: 166 PGVVQSIKLITRDASERVIRYAFEYARAIGRPR-VIVVHKSTIQRLADGLF----VNVAK 220 G+ ++ + + ER R A + + +G V+ + GLF +++ + Sbjct: 188 EGIASALARLDQRHVERAARAAVQALQLMGIAHPVVGLMGINPHAGEGGLFGRDDIDITE 247 Query: 221 ELSKEYPDLTLETELIDNSVLKVVTNPSAYTDAVSVCPNLY---GDILSDLNSGLSAGSL 277 ++++ D T + ++TNP V V +Y G I L +G + +L Sbjct: 248 PVARKLRD-DGMTVIGPQGADLLLTNP---DIDVFVA--MYHDQGHIPVKLRAGRHSAAL 301 Query: 278 GLTPSANIGHKISIFEAV-HGSAPDIAGQDKANPTALL 314 + +F +V HGS DIAG A+P LL Sbjct: 302 SIGAG-------VLFSSVGHGSGFDIAGTLLADPAPLL 332 >2XIG-A nrPDB Length = 150 Score = 29.1 bits (64), Expect = 3.3, Method: Composition-based stats. Identities = 13/64 (20%), Positives = 23/64 (35%), Gaps = 1/64 (1%) Query: 170 QSIKLITRDASERVIRYAFEYARAIGRPRVIVVHKSTIQRLADGLFVNVAKELSKEYPDL 229 + I+ + + R +E A +I +H I AD N E+ K+Y Sbjct: 72 EKENFISVLETSKSGRR-YEIAAKEHHDHIICLHCGKIIEFADPEIENRQNEVVKKYQAK 130 Query: 230 TLET 233 + Sbjct: 131 LISH 134 >1MZB-A nrPDB Length = 136 Score = 29.1 bits (64), Expect = 3.4, Method: Composition-based stats. Identities = 14/92 (15%), Positives = 32/92 (34%), Gaps = 9/92 (9%) Query: 154 EGEYSGI-EHIVCPGVVQSIKLITRDASERVI--------RYAFEYARAIGRPRVIVVHK 204 E Y + E G+ +++T+ + ++ FE A + ++ V Sbjct: 38 EDVYKALMEAGEDVGLATVYRVLTQFEAAGLVVRHNFDGGHAVFELADSGHHDHMVCVDT 97 Query: 205 STIQRLADGLFVNVAKELSKEYPDLTLETELI 236 + D KE+ +E ++ L+ Sbjct: 98 GEVIEFMDAEIEKRQKEIVRERGFELVDHNLV 129 >6NF8-L nrPDB Length = 139 Score = 29.1 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 12 RRFLATVKQP-SIGRYTGKPNPSTGKYTVSFIEGDG 46 R F+ K+P S R + STG+ V FI G+G Sbjct: 64 RTFIRKPKKPNSANRKCCRVRLSTGREAVCFIPGEG 99 >6GAW-AL nrPDB Length = 139 Score = 29.1 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 12 RRFLATVKQP-SIGRYTGKPNPSTGKYTVSFIEGDG 46 R F+ K+P S R + STG+ V FI G+G Sbjct: 64 RTFIRKPKKPNSANRKCCRVRLSTGREAVCFIPGEG 99 >5AJ4-AL nrPDB Length = 109 Score = 29.1 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 19/36 (52%), Gaps = 1/36 (2%) Query: 12 RRFLATVKQP-SIGRYTGKPNPSTGKYTVSFIEGDG 46 R F+ K+P S R + STG+ V FI G+G Sbjct: 34 RTFIRKPKKPNSANRKCCRVRLSTGREAVCFIPGEG 69 >1PW4-A nrPDB Length = 451 Score = 28.8 bits (63), Expect = 3.8, Method: Composition-based stats. Identities = 20/63 (31%), Positives = 28/63 (44%), Gaps = 4/63 (6%) Query: 271 GLSAGSLGLTPSA-NIGHKISIFEAVHGSAPDIAGQDKANPTALLLSSVMMLNHMGLTNH 329 G S G LG S +I + S F + GS D + P L+L++ +ML MG Sbjct: 58 GFSRGDLGFALSGISIAYGFSKF--IMGSVSDRSNPRVFLPAGLILAAAVML-FMGFVPW 114 Query: 330 ADQ 332 A Sbjct: 115 ATS 117 >1VBH-A nrPDB Length = 876 Score = 28.8 bits (63), Expect = 4.1, Method: Composition-based stats. Identities = 7/37 (18%), Positives = 15/37 (40%) Query: 79 NGLTTIPDPAVQSITKNLVALKGPLATPIGKGHRSLN 115 P + + ++A+ +P K +RS+N Sbjct: 194 AKGEPFPSDPKKQLELAVLAVFNSWESPRAKKYRSIN 230 >2RFG-A nrPDB Length = 297 Score = 28.8 bits (63), Expect = 4.3, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 26/77 (33%), Gaps = 17/77 (22%) Query: 255 SVCPNLYGDILSDLNSGLSA-----GSLGLTPSANIGHKISIFEAVH------------G 297 + P + G + +GL G+ GL P G ++ E H G Sbjct: 9 MITPFINGQVDEKALAGLVDWQIKHGAHGLVPVGTTGESPTLTEEEHKRVVALVAEQAQG 68 Query: 298 SAPDIAGQDKANPTALL 314 P IAG NP + Sbjct: 69 RVPVIAGAGSNNPVEAV 85 >2FTP-A nrPDB Length = 302 Score = 28.8 bits (63), Expect = 4.4, Method: Composition-based stats. Identities = 19/81 (23%), Positives = 30/81 (37%), Gaps = 4/81 (4%) Query: 35 GKYTVSFIEGDGIGPEISKSVKKIFSAA--NVPIEWESCDVSPIFVNGLTTIPDPAVQSI 92 G Y VS GD IG + + +++ A VP E + + L I ++ I Sbjct: 172 GCYEVSL--GDTIGVGTAGATRRLIEAVASEVPRERLAGHFHDTYGQALANIYASLLEGI 229 Query: 93 TKNLVALKGPLATPIGKGHRS 113 ++ G P KG Sbjct: 230 AVFDSSVAGLGGCPYAKGATG 250 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.146 0.414 Lambda K H 0.267 0.0447 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,290,474 Number of Sequences: 36641 Number of extensions: 679521 Number of successful extensions: 2399 Number of sequences better than 10.0: 71 Number of HSP's better than 10.0 without gapping: 76 Number of HSP's successfully gapped in prelim test: 35 Number of HSP's that attempted gapping in prelim test: 1903 Number of HSP's gapped (non-prelim): 124 length of query: 369 length of database: 10,336,785 effective HSP length: 98 effective length of query: 271 effective length of database: 6,745,967 effective search space: 1828157057 effective search space used: 1828157057 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.1 bits) S2: 60 (27.6 bits)