BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P27986 (724 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 5M6U-B nrPDB 1495 0.0 1PBW-A nrPDB 437 e-123 6MRP-B nrPDB 365 e-101 6D81-A nrPDB 362 e-100 2XS6-A nrPDB 85 9e-17 1XA6-A nrPDB 70 4e-12 3BYI-A nrPDB 69 7e-12 3CXL-A nrPDB 69 1e-11 5C5S-A nrPDB 67 4e-11 2OSA-A nrPDB 65 1e-10 3FK2-A nrPDB 60 3e-09 4JGH-A nrPDB 59 7e-09 5IRC-A nrPDB 58 2e-08 2EE4-A nrPDB 57 2e-08 2VIF-A nrPDB 57 2e-08 2CRH-A nrPDB 57 3e-08 2LCT-A nrPDB 56 6e-08 6GVC-R nrPDB 55 1e-07 2EOB-A nrPDB 54 2e-07 4XEY-B nrPDB 52 7e-07 2FO0-A nrPDB 52 7e-07 6AMW-A nrPDB 52 7e-07 3T04-A nrPDB 52 1e-06 2BBU-A nrPDB 51 2e-06 2ABL-A nrPDB 51 2e-06 2PLE-A nrPDB 50 2e-06 5MY3-A nrPDB 50 3e-06 2HMH-A nrPDB 50 4e-06 4XI2-A nrPDB 50 5e-06 1AD5-A nrPDB 49 8e-06 4GL9-E nrPDB 49 8e-06 1K9A-A nrPDB 49 1e-05 3IUG-A nrPDB 48 1e-05 1F7C-A nrPDB 47 2e-05 2MBG-A nrPDB 47 3e-05 2EKX-A nrPDB 46 5e-05 2LQW-A nrPDB 46 7e-05 2KK6-A nrPDB 45 1e-04 1GRI-A nrPDB 45 1e-04 6C7Y-B nrPDB 44 2e-04 2EYZ-A nrPDB 44 2e-04 6F3F-A nrPDB 43 4e-04 5JCP-B nrPDB 43 4e-04 2H8H-A nrPDB 43 4e-04 4FL3-A nrPDB 43 5e-04 5C2K-A nrPDB 42 8e-04 1A81-A nrPDB 42 9e-04 5JD0-A nrPDB 42 0.001 4H1O-A nrPDB 41 0.002 4M4Z-A nrPDB 39 0.010 2QV2-A nrPDB 39 0.010 3PVL-A nrPDB 39 0.011 3WPS-A nrPDB 38 0.015 6CMQ-A nrPDB 38 0.016 6R3V-A nrPDB 38 0.017 6C5X-D nrPDB 37 0.024 2IZV-A nrPDB 37 0.034 2OZO-A nrPDB 37 0.037 4XZ1-A nrPDB 36 0.051 1OW3-A nrPDB 36 0.055 3EAP-A nrPDB 35 0.086 1GRN-B nrPDB 35 0.089 2CUC-A nrPDB 35 0.10 3PS5-A nrPDB 35 0.11 2B3O-A nrPDB 35 0.12 4N78-F nrPDB 35 0.13 4C7Y-A nrPDB 35 0.15 2X3W-D nrPDB 34 0.21 6F55-A nrPDB 34 0.24 2ED0-A nrPDB 33 0.36 3KUQ-A nrPDB 33 0.40 4E93-A nrPDB 33 0.50 1Y1U-A nrPDB 32 0.86 4BNE-A nrPDB 32 0.92 2ZR2-A nrPDB 32 1.0 3HAJ-A nrPDB 32 1.1 1BF5-A nrPDB 32 1.2 1K4U-S nrPDB 32 1.3 2CS0-A nrPDB 32 1.3 2CR4-A nrPDB 31 1.6 1YVL-A nrPDB 31 1.8 1SPK-A nrPDB 30 2.9 1WXU-A nrPDB 30 3.2 5U06-A nrPDB 29 5.6 6E11-1 nrPDB 29 7.3 5OFO-C nrPDB 29 9.2 2M7L-A nrPDB 28 9.7 >5M6U-B nrPDB Length = 724 Score = 1495 bits (3871), Expect = 0.0, Method: Compositional matrix adjust. Identities = 720/724 (99%), Positives = 723/724 (99%) Query: 1 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN 60 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN Sbjct: 1 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN 60 Query: 61 ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE 120 ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE Sbjct: 61 ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE 120 Query: 121 QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH 180 QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH Sbjct: 121 QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH 180 Query: 181 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL 240 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL Sbjct: 181 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL 240 Query: 241 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE 300 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE Sbjct: 241 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE 300 Query: 301 RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA 360 RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA Sbjct: 301 RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA 360 Query: 361 STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL 420 STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL Sbjct: 361 STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL 420 Query: 421 DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMK 480 DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYE+YTRTSQEIQMK Sbjct: 421 DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMK 480 Query: 481 RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIID 540 RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNE EIQRIMHNY+KLKSRISEI+D Sbjct: 481 RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNETEIQRIMHNYEKLKSRISEIVD 540 Query: 541 SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN 600 SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN Sbjct: 541 SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN 600 Query: 601 ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS 660 ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS Sbjct: 601 ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS 660 Query: 661 VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA Sbjct: 661 VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 Query: 721 QQRR 724 QQRR Sbjct: 721 QQRR 724 >1PBW-A nrPDB Length = 216 Score = 437 bits (1124), Expect = e-123, Method: Compositional matrix adjust. Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 105 EADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL 164 EADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL Sbjct: 2 EADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL 61 Query: 165 LDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLK 224 LDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLK Sbjct: 62 LDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLK 121 Query: 225 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTE 284 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTE Sbjct: 122 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTE 181 Query: 285 NLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN 319 NLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN Sbjct: 182 NLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN 216 >6MRP-B nrPDB Length = 220 Score = 365 bits (937), Expect = e-101, Method: Compositional matrix adjust. Identities = 198/216 (91%), Positives = 206/216 (95%), Gaps = 1/216 (0%) Query: 104 TEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQ 163 TEAD QQA TLPDLAEQFAPPD+APPLLIKLVEAIEKKGLECSTLYRTQSSSN AELRQ Sbjct: 6 TEAD-SQQASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQ 64 Query: 164 LLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLL 223 LLDCDT S+DLEM DVHVLADAFKRYLLDLPNPVIP AV SE+ISLAPEVQSSEEYIQLL Sbjct: 65 LLDCDTASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLL 124 Query: 224 KKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNT 283 KKLI SPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSE+FSP+LFRF AASS+NT Sbjct: 125 KKLIESPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENT 184 Query: 284 ENLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN 319 E+LIK+IEILISTEWNERQPAPALPPKPPKPTTVAN Sbjct: 185 EHLIKIIEILISTEWNERQPAPALPPKPPKPTTVAN 220 >6D81-A nrPDB Length = 193 Score = 362 bits (929), Expect = e-100, Method: Compositional matrix adjust. Identities = 178/193 (92%), Positives = 186/193 (96%) Query: 110 QQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDT 169 QQA TLPDLAEQFAPPD+APPLLIKLVEAIEKKGLECSTLYRTQSSSN AELRQLLDCDT Sbjct: 1 QQASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDT 60 Query: 170 PSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRS 229 S+DLEM DVHVLADAFKRYLLDLPNPVIP AV SE+ISLAPEVQSSEEYIQLLKKLIRS Sbjct: 61 ASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLLKKLIRS 120 Query: 230 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKV 289 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSE+FSP+LFRF AASS+NTE+LIK+ Sbjct: 121 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENTEHLIKI 180 Query: 290 IEILISTEWNERQ 302 IEILISTEWNERQ Sbjct: 181 IEILISTEWNERQ 193 >2XS6-A nrPDB Length = 214 Score = 85.1 bits (209), Expect = 9e-17, Method: Composition-based stats. Identities = 53/160 (33%), Positives = 82/160 (51%), Gaps = 14/160 (8%) Query: 109 EQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCD 168 + LTLPDL EQF+PPD+APPLL+KLVEAIE+ GL+ + YR + + D Sbjct: 21 QSMGLTLPDLPEQFSPPDVAPPLLVKLVEAIERTGLDSESHYRPELPAPRT--------D 72 Query: 169 TPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIR 228 D++ D LAD K +LL LP P++ +E ++ E + + Sbjct: 73 WSLSDVDQWDTAALADGIKSFLLALPAPLVTPEASAE------ARRALREAAGPVGPALE 126 Query: 229 SPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIF 268 P++P LTL++LL+H ++++ + R L F Sbjct: 127 PPTLPLHRALTLRFLLQHLGRVARRAPALGPAVRALGATF 166 >1XA6-A nrPDB Length = 466 Score = 69.7 bits (169), Expect = 4e-12, Method: Compositional matrix adjust. Identities = 49/190 (25%), Positives = 96/190 (50%), Gaps = 12/190 (6%) Query: 117 DLAEQFAPPDIAPPLLIKL-VEAIEKKGLECSTLYRTQS-SSNLAELRQLLDCDTPSVDL 174 DL + P+++ + + IE +GL+ LYR + ++ +++ D D D+ Sbjct: 276 DLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADI 335 Query: 175 EM---IDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPS 231 D++++ A K Y DLP PVI YS+ I A ++ +++E ++ + +++ Sbjct: 336 SANVYPDINIITGALKLYFRDLPIPVITYDTYSKFID-AAKISNADERLEAVHEVLML-- 392 Query: 232 IPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK--- 288 +P ++ TL+YL+ H K++ N +NA L +F P L R S+ T + ++ Sbjct: 393 LPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQK 452 Query: 289 -VIEILISTE 297 +++ILI E Sbjct: 453 LIVQILIENE 462 Score = 37.7 bits (86), Expect = 0.016, Method: Compositional matrix adjust. Identities = 32/98 (32%), Positives = 49/98 (50%), Gaps = 9/98 (9%) Query: 334 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS 393 + G ISRE+ +E L +G +++R+ S + G YTL LR G ++FH DGK+ F Sbjct: 58 FHGIISREQADE-LLGGVEGAYILRE-SQRQPGCYTLALRFGNQTLNYRLFH-DGKH-FV 113 Query: 394 DPLTFSSVVE-----LINHYRNESLAQYNPKLDVKLLY 426 F S+ + LI Y A+Y K+ +Y Sbjct: 114 GEKRFESIHDLVTDGLITLYIETKAAEYISKMTTNPIY 151 >3BYI-A nrPDB Length = 214 Score = 68.9 bits (167), Expect = 7e-12, Method: Compositional matrix adjust. Identities = 47/180 (26%), Positives = 94/180 (52%), Gaps = 21/180 (11%) Query: 128 APPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL---------LDCDTPSVDLEMID 178 P + + +EA+EK+GL+ +YR S NLA +++L L+ D D + D Sbjct: 35 VPWFVKQCIEAVEKRGLDVDGIYRV--SGNLATIQKLRFIVNQEEKLNLD----DSQWED 88 Query: 179 VHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWL 238 +HV+ A K + +LP P+ P + + + + A + Q + I+ +K L++ P++ Sbjct: 89 IHVVTGALKMFFRELPEPLFPYSFFEQFVE-AIKKQDNNTRIEAVKSLVQKLPPPNRD-- 145 Query: 239 TLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLI---KVIEILIS 295 T++ L H K+ +SKNL++ + L +F P L R + + +++ ++ E+++S Sbjct: 146 TMKVLFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLS 205 >3CXL-A nrPDB Length = 463 Score = 68.6 bits (166), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 12/177 (6%) Query: 130 PLLIKL-VEAIEKKGLECSTLYRTQSSSNLAE-LRQLLDCDTPSVDLEMI---DVHVLAD 184 P+++ + + IE +GL LYR S+L E ++ D D D+ + D++++ Sbjct: 286 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 345 Query: 185 AFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLL 244 A K Y DLP P+I Y + I A ++ +E ++ L + ++ +P + TL+YL+ Sbjct: 346 ALKLYFRDLPIPLITYDAYPKFIESA-KIMDPDEQLETLHEALK--LLPPAHCETLRYLM 402 Query: 245 KHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK----VIEILISTE 297 H +++ +NL+NA L +F P L R + N I+ V+E+LI E Sbjct: 403 AHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNE 459 >5C5S-A nrPDB Length = 232 Score = 66.6 bits (161), Expect = 4e-11, Method: Compositional matrix adjust. Identities = 50/174 (28%), Positives = 82/174 (47%), Gaps = 8/174 (4%) Query: 128 APPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDCDTPSVDLEMIDVHVLADAF 186 P +L KL+E +E GL LYR ++N ELRQ L D +V LE +H + Sbjct: 28 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 87 Query: 187 KRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKH 246 K++L +LP P++ A Y + + + E+ + L P H +L+ L+ H Sbjct: 88 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEHLPEANHN---SLERLIFH 144 Query: 247 FFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE 300 K++ N ++ L+ IF+P L R DN++ L + ++L T E Sbjct: 145 LVKVALLEDVNRMSPGALAIIFAPCLLR----CPDNSDPLTSMKDVLKITTCVE 194 >2OSA-A nrPDB Length = 202 Score = 65.1 bits (157), Expect = 1e-10, Method: Compositional matrix adjust. Identities = 50/177 (28%), Positives = 89/177 (50%), Gaps = 12/177 (6%) Query: 130 PLLIKL-VEAIEKKGLECSTLYRTQSSSNLAE-LRQLLDCDTPSVDLEMI---DVHVLAD 184 P+++ + + IE +GL LYR S+L E ++ D D D+ + D++++ Sbjct: 25 PMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADISVNMYEDINIITG 84 Query: 185 AFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLL 244 A K Y DLP P+I Y + I A ++ +E ++ L + ++ +P + TL+YL+ Sbjct: 85 ALKLYFRDLPIPLITYDAYPKFIESA-KIMDPDEQLETLHEALK--LLPPAHCETLRYLM 141 Query: 245 KHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK----VIEILISTE 297 H +++ +NL+NA L +F P L R + N I+ V+E+LI E Sbjct: 142 AHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQRLVVELLIKNE 198 >3FK2-A nrPDB Length = 246 Score = 60.1 bits (144), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 52/199 (26%), Positives = 95/199 (47%), Gaps = 11/199 (5%) Query: 102 SKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAE 160 S T+A E +P L P P + + +E IE GL +YR + S + Sbjct: 43 SITKATWESNYFGVP-LTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMES 101 Query: 161 LRQLLDCDTPSVDLEMID--VHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEE 218 L++ D D ++DL D V+ +A A K + +LP+P++P + +++ A ++ E+ Sbjct: 102 LQRQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVE-AHKINDREQ 159 Query: 219 YIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAA 278 + LK++++ P + +Y++ H K+S + NL+ + LS F P L R + Sbjct: 160 KLHALKEVLK--KFPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFS 217 Query: 279 SSD---NTENLIKVIEILI 294 + D T +IE+ I Sbjct: 218 TMDALTATRTYQTIIELFI 236 >4JGH-A nrPDB Length = 173 Score = 58.9 bits (141), Expect = 7e-09, Method: Compositional matrix adjust. Identities = 32/90 (35%), Positives = 49/90 (54%), Gaps = 12/90 (13%) Query: 328 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTL--RKGGNNKLIKIFH 385 L WYWG ++ E EKL++ +GTFL+RD+S H DY LT+ + ++I + Sbjct: 18 LGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSS---HSDYLLTISVKTSAGPTNLRIEY 74 Query: 386 RDGKYGFSDPLT-------FSSVVELINHY 408 +DGK+ + F SVV LI++Y Sbjct: 75 QDGKFRLDSIICVKSKLKQFDSVVHLIDYY 104 Score = 29.3 bits (64), Expect = 6.5, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 624 WNVGSSNRNKAENLLRGKRDGTFLVRESS 652 W GS N+A+ L+ +GTFL+R+SS Sbjct: 23 WYWGSMTVNEAKEKLKEAPEGTFLIRDSS 51 >5IRC-A nrPDB Length = 201 Score = 57.8 bits (138), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 47/177 (26%), Positives = 91/177 (51%), Gaps = 11/177 (6%) Query: 125 PDIAPPLLI-KLVEAIEKKGLECSTLYRTQSS-SNLAELRQLLDCDTPSVDLEMID--VH 180 P+ P+ I + +E IE GL +YR + S + L++ D D ++DL D V+ Sbjct: 19 PEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQFDQDH-NLDLAEKDFTVN 77 Query: 181 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL 240 +A A K + +LP+P++P ++ +++ A ++ E+ + LK++++ P + Sbjct: 78 TVAGAMKSFFSELPDPLVPYSMQIDLVE-AHKINDREQKLHALKEVLK--KFPKENHEVF 134 Query: 241 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD---NTENLIKVIEILI 294 +Y++ H ++S + NL+ + LS F P L R +S D T + +IE+ I Sbjct: 135 KYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDALTATRSYQTIIELFI 191 >2EE4-A nrPDB Length = 209 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 45/148 (30%), Positives = 78/148 (52%), Gaps = 6/148 (4%) Query: 130 PLLI-KLVEAIEKKGLECSTLYRTQSS-SNLAELRQLLDCDTPSVDLEM-IDVHVLADAF 186 PL + K VE IE GL LYR + ++ +++ D D + M + V+ +A A Sbjct: 28 PLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFDQDHNINLVSMEVTVNAVAGAL 87 Query: 187 KRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKH 246 K + DLP+P+IP +++ E++ A ++ E + LK++++ P Y + +Y++ H Sbjct: 88 KAFFADLPDPLIPYSLHPELLE-AAKIPDKTERLHALKEIVKKFH-PVNYDV-FRYVITH 144 Query: 247 FFKLSQTSSKNLLNARVLSEIFSPMLFR 274 ++SQ NL+ A LS F P L R Sbjct: 145 LNRVSQQHKINLMTADNLSICFWPTLMR 172 >2VIF-A nrPDB Length = 141 Score = 57.4 bits (137), Expect = 2e-08, Method: Compositional matrix adjust. Identities = 39/119 (32%), Positives = 58/119 (48%), Gaps = 14/119 (11%) Query: 328 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 L WYWG I+R E KL + DG+FLVRD+S + +L+ R G +I H + Sbjct: 21 LAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRY-LLSLSFRSHGKTLHTRIEHSN 79 Query: 388 GKYGF---SDPLTFSSVVELINH----YRNESLAQYNPKL------DVKLLYPVSKYQQ 433 G++ F D +S+V+LI H N + +L V+L PVS++ Q Sbjct: 80 GRFSFYEQPDVEGHTSIVDLIEHSIGDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQ 138 Score = 30.0 bits (66), Expect = 3.7, Method: Compositional matrix adjust. Identities = 25/87 (28%), Positives = 43/87 (49%), Gaps = 3/87 (3%) Query: 614 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESS-KQGCYACSVVVDGEVKHCVI 672 E+L ++ W G R +AE L DG+FLVR+SS + + S G+ H I Sbjct: 16 EELKKLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRYLLSLSFRSHGKTLHTRI 75 Query: 673 NKTATGYGFAEPYNL--YSSLKELVLH 697 + + F E ++ ++S+ +L+ H Sbjct: 76 EHSNGRFSFYEQPDVEGHTSIVDLIEH 102 >2CRH-A nrPDB Length = 138 Score = 57.0 bits (136), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 41/112 (36%), Positives = 54/112 (48%), Gaps = 5/112 (4%) Query: 614 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVI 672 +DL H W G R AE++L + DGTFLVR+ K +A S+ + EVKH I Sbjct: 21 QDLSVH---LWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI 77 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 724 TA G + L ELV YQ SL SL+ TL +P ++R Sbjct: 78 -MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKR 128 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Query: 333 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 392 WY G + R L + +DGTFLVR K ++ ++++ K IKI +G Y Sbjct: 28 WYAGPMERAGAESILANRSDGTFLVRQ-RVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 86 Query: 393 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 427 ++ F + EL+ Y+ SL LD L +P Sbjct: 87 TEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 121 >2LCT-A nrPDB Length = 107 Score = 55.8 bits (133), Expect = 6e-08, Method: Compositional matrix adjust. Identities = 40/105 (38%), Positives = 51/105 (48%), Gaps = 5/105 (4%) Query: 614 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVI 672 +DL H W G R AE++L + DGTFLVR+ K +A S+ + EVKH I Sbjct: 4 QDLSVH---LWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI 60 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 717 TA G + L ELV YQ SL SL+ TL +P Sbjct: 61 -MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 104 Score = 50.1 bits (118), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 29/95 (30%), Positives = 45/95 (47%), Gaps = 1/95 (1%) Query: 333 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 392 WY G + R L + +DGTFLVR K ++ ++++ K IKI +G Y Sbjct: 11 WYAGPMERAGAESILANRSDGTFLVRQ-RVKDAAEFAISIKYNVEVKHIKIMTAEGLYRI 69 Query: 393 SDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 427 ++ F + EL+ Y+ SL LD L +P Sbjct: 70 TEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 104 >6GVC-R nrPDB Length = 231 Score = 55.1 bits (131), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 41/155 (26%), Positives = 77/155 (49%), Gaps = 20/155 (12%) Query: 130 PLLIKL-VEAIEKKGLECSTLYRTQSSSNLAELRQL---------LDCDTPSVDLEMIDV 179 P +KL +E +E+ GL+ +YR S NLA +++L LD + D + D+ Sbjct: 55 PKFVKLCIEHVEEHGLDVDGIYRV--SGNLAVIQKLRFAVNHDEKLDLN----DSKWEDI 108 Query: 180 HVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLT 239 HV+ A K + +LP P+ +++ ++ Q + + +K LIR P+Q T Sbjct: 109 HVITGALKMFFRELPEPLFTFNHFNDFVNAIK--QEPRQRVTAVKDLIRQLPKPNQD--T 164 Query: 240 LQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFR 274 +Q L +H ++ + KN + + ++ +F P L + Sbjct: 165 MQILFRHLKRVIENGEKNRMTYQSIAIVFGPTLLK 199 >2EOB-A nrPDB Length = 124 Score = 53.9 bits (128), Expect = 2e-07, Method: Compositional matrix adjust. Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 7/101 (6%) Query: 619 HDEKTWNVGSSNRNKAENLL-RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTAT 677 H+ K W +R +AE++L R RDG FL+R+ YA + G+VKHC IN+ Sbjct: 16 HESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGR 75 Query: 678 GYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + SL ELV +Y+ +L + + L YPV Sbjct: 76 HFVLGTS-AYFESLVELVSYYEKHALYR-----KMRLRYPV 110 >4XEY-B nrPDB Length = 408 Score = 52.4 bits (124), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 6/100 (6%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 8 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 67 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + +++L ELV H H+++ D L TL YP Sbjct: 68 KLYVSSESRFNTLAELVHH--HSTVA---DGLITTLHYPA 102 Score = 41.2 bits (95), Expect = 0.002, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 47/93 (50%), Gaps = 12/93 (12%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 M + SL+ WY G +SR L +G+FLVR++ + G +++LR G Sbjct: 1 MASVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEG----- 54 Query: 382 KIFH------RDGKYGFSDPLTFSSVVELINHY 408 +++H DGK S F+++ EL++H+ Sbjct: 55 RVYHYRINTASDGKLYVSSESRFNTLAELVHHH 87 >2FO0-A nrPDB Length = 495 Score = 52.4 bits (124), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 6/100 (6%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 100 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 159 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + +++L ELV H H+++ D L TL YP Sbjct: 160 KLYVSSESRFNTLAELVHH--HSTVA---DGLITTLHYPA 194 Score = 45.4 bits (106), Expect = 9e-05, Method: Compositional matrix adjust. Identities = 41/148 (27%), Positives = 67/148 (45%), Gaps = 25/148 (16%) Query: 272 LFRFSAASSDNTENL-----IKVIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNM 326 L+ F AS DNT ++ ++V+ + EW E Q P T N Sbjct: 46 LYDF-VASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN------- 97 Query: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH- 385 SL+ WY G +SR L +G+FLVR++ + G +++LR G +++H Sbjct: 98 SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEG-----RVYHY 151 Query: 386 -----RDGKYGFSDPLTFSSVVELINHY 408 DGK S F+++ EL++H+ Sbjct: 152 RINTASDGKLYVSSESRFNTLAELVHHH 179 >6AMW-A nrPDB Length = 255 Score = 52.4 bits (124), Expect = 7e-07, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 6/100 (6%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 142 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 201 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + +++L ELV H H+++ D L TL YP Sbjct: 202 KLYVSSESRFNTLAELVHH--HSTVA---DGLITTLHYPA 236 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 49/176 (27%), Positives = 76/176 (43%), Gaps = 30/176 (17%) Query: 272 LFRFSAASSDNTENLIK-----VIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNM 326 L+ F AS DNT ++ K V+ + EW E Q P T N Sbjct: 88 LYDF-VASGDNTLSITKGEKLRVLGYNHNGEWAEAQTKNGQGWVPSNYITPVN------- 139 Query: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH- 385 SL+ WY G +SR L +G+FLVR++ + G +++LR G +++H Sbjct: 140 SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSP-GQRSISLRYEG-----RVYHY 193 Query: 386 -----RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV 436 DGK S F+++ EL++H+ ++A L L YP K + V Sbjct: 194 RINTASDGKLYVSSESRFNTLAELVHHH--STVAD---GLITTLHYPAPKRNKPTV 244 >3T04-A nrPDB Length = 123 Score = 52.0 bits (123), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 6/100 (6%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 14 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 73 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + +++L ELV H H+++ D L TL YP Sbjct: 74 KLYVSSESRFNTLAELVHH--HSTVA---DGLITTLHYPA 108 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 33/116 (28%), Positives = 55/116 (47%), Gaps = 17/116 (14%) Query: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH- 385 SL+ WY G +SR L +G+FLVR++ + G +++LR G +++H Sbjct: 12 SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSP-GQRSISLRYEG-----RVYHY 65 Query: 386 -----RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV 436 DGK S F+++ EL++H+ ++A L L YP K + V Sbjct: 66 RINTASDGKLYVSSESRFNTLAELVHHH--STVAD---GLITTLHYPAPKRNKPTV 116 >2BBU-A nrPDB Length = 164 Score = 51.2 bits (121), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 +N LQ++ +YW ++ E N L GTFL+RD+S + H +TL+++ K + Sbjct: 14 VNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRH-FFTLSVKTQSGTKNL 72 Query: 382 KIFHRDGKYGF-SDPLT------FSSVVELINHY 408 +I G + SDP + F V++L++HY Sbjct: 73 RIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 106 >2ABL-A nrPDB Length = 163 Score = 50.8 bits (120), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 36/100 (36%), Positives = 54/100 (54%), Gaps = 6/100 (6%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 68 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 127 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + +++L ELV H H+++ D L TL YP Sbjct: 128 KLYVSSESRFNTLAELVHH--HSTVA---DGLITTLHYPA 162 Score = 44.7 bits (104), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 42/148 (28%), Positives = 66/148 (44%), Gaps = 25/148 (16%) Query: 272 LFRFSAASSDNTENLIK-----VIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNM 326 L+ F AS DNT ++ K V+ + EW E Q P T N Sbjct: 14 LYDF-VASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN------- 65 Query: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH- 385 SL+ WY G +SR L +G+FLVR++ + G +++LR G +++H Sbjct: 66 SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSP-GQRSISLRYEG-----RVYHY 119 Query: 386 -----RDGKYGFSDPLTFSSVVELINHY 408 DGK S F+++ EL++H+ Sbjct: 120 RINTASDGKLYVSSESRFNTLAELVHHH 147 >2PLE-A nrPDB Length = 105 Score = 50.4 bits (119), Expect = 2e-06, Method: Compositional matrix adjust. Identities = 31/101 (30%), Positives = 52/101 (51%), Gaps = 8/101 (7%) Query: 619 HDEKTWNVGSSNRNKAENLL-RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTAT 677 H+ K W S R +AE++L R RDG FLVR+ ++ YA S +G++KHC + + Sbjct: 6 HESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEGQ 65 Query: 678 GYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + SL +L+ +Y+ L + + L YP+ Sbjct: 66 TVMLGN--SEFDSLVDLISYYEKHPLYR-----KMKLRYPI 99 >5MY3-A nrPDB Length = 226 Score = 50.4 bits (119), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 41/187 (21%), Positives = 94/187 (50%), Gaps = 13/187 (6%) Query: 126 DIAPPLLIKLVEAIEKKGLECSTLYRTQSSS-NLAELRQLLDCDTPSVDLEM-------I 177 D+ P ++ + + I+K GL+ +YR ++ ++++L++ +D D ++ + + Sbjct: 35 DMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDS 94 Query: 178 DVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPH-QY 236 D++++ K + LP+ V+P A+ SE I + +++ + LI ++P QY Sbjct: 95 DIYLVGSLLKTFFASLPDSVLPKALSSE-IKVCLQIEDPTTRKNFMHGLIY--NLPDAQY 151 Query: 237 WLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILIST 296 W TL+ L+ H ++ ++N +N R L I+ P + + +++ I +E+L+ Sbjct: 152 W-TLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDVNFQIMAMEVLLEV 210 Query: 297 EWNERQP 303 +P Sbjct: 211 SDQAFEP 217 >2HMH-A nrPDB Length = 152 Score = 50.1 bits (118), Expect = 4e-06, Method: Compositional matrix adjust. Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 +N LQ++ +YW ++ E N L GTFL+RD+S + H +TL+++ K + Sbjct: 25 VNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRH-FFTLSVKTQSGTKNL 83 Query: 382 KIFHRDGKYGF-SDPLT------FSSVVELINHY 408 +I G + SDP + F V++L++HY Sbjct: 84 RIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 117 >4XI2-A nrPDB Length = 446 Score = 49.7 bits (117), Expect = 5e-06, Method: Compositional matrix adjust. Identities = 34/107 (31%), Positives = 54/107 (50%), Gaps = 12/107 (11%) Query: 624 WNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCYACSVVV------DGEVKHCVINKTA 676 W R++AE LL+ + ++G F+VR+SSK G Y SV G ++H V+ T Sbjct: 68 WYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVFAKSTGEPQGVIRHYVVCSTP 127 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 723 + +L+S++ EL+ ++QH S L L YPV Q + Sbjct: 128 QSQYYLAEKHLFSTIPELINYHQHNS-----AGLISRLKYPVSKQNK 169 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 31/112 (27%), Positives = 57/112 (50%), Gaps = 15/112 (13%) Query: 327 SLQDAEWYWGDISREEVNEKLR-DTADGTFLVRDASTKMHGDYTLTLR-------KGGNN 378 S++ EWY ++R + + L+ + +G F+VRD+S G YT+++ +G Sbjct: 62 SIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKA--GKYTVSVFAKSTGEPQGVIR 119 Query: 379 KLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 430 + +Y ++ FS++ ELIN++++ S L +L YPVSK Sbjct: 120 HYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNSAG-----LISRLKYPVSK 166 >1AD5-A nrPDB Length = 438 Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 34/99 (34%), Positives = 56/99 (56%), Gaps = 11/99 (11%) Query: 327 SLQDAEWYWGDISREEVNEKLRDTAD--GTFLVRDASTKMHGDYTLTLR-----KGGNNK 379 SL+ EW++ ISR++ +L + G+F++RD+ T G Y+L++R +G K Sbjct: 60 SLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETT-KGSYSLSVRDYDPRQGDTVK 118 Query: 380 LIKIFHRD-GKYGFSDPLTFSSVVELINHYR--NESLAQ 415 KI D G + S TFS++ EL++HY+ N+ L Q Sbjct: 119 HYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQ 157 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 32/107 (29%), Positives = 50/107 (46%), Gaps = 13/107 (12%) Query: 624 WNVGSSNRNKAEN--LLRGKRDGTFLVRES-SKQGCYACSVV-----VDGEVKHCVINKT 675 W +R AE L G G+F++R+S + +G Y+ SV VKH I Sbjct: 66 WFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYKIRTL 125 Query: 676 ATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 G + P + +S+L+ELV HY+ + ND L L+ P + + Sbjct: 126 DNGGFYISPRSTFSTLQELVDHYK-----KGNDGLCQKLSVPCMSSK 167 >4GL9-E nrPDB Length = 143 Score = 48.9 bits (115), Expect = 8e-06, Method: Compositional matrix adjust. Identities = 29/94 (30%), Positives = 50/94 (53%), Gaps = 8/94 (8%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 +N LQ++ +YW ++ E N L GTFL+RD+S + H +TL+++ K + Sbjct: 19 VNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRH-FFTLSVKTQSGTKNL 77 Query: 382 KIFHRDGKYGF-SDPLT------FSSVVELINHY 408 +I G + SDP + F V++L++HY Sbjct: 78 RIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 111 >1K9A-A nrPDB Length = 450 Score = 48.5 bits (114), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 45/92 (48%), Gaps = 1/92 (1%) Query: 321 GMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKL 380 G+ L W+ G I+RE+ L G FLVR+ ST GDYTL + G + Sbjct: 70 GVKAGTKLSLMPWFHGKITREQAERLLYPPETGLFLVRE-STNYPGDYTLCVSCEGKVEH 128 Query: 381 IKIFHRDGKYGFSDPLTFSSVVELINHYRNES 412 +I + K + + F ++++L+ HY ++ Sbjct: 129 YRIMYHASKLSIDEEVYFENLMQLVEHYTTDA 160 Score = 37.0 bits (84), Expect = 0.031, Method: Compositional matrix adjust. Identities = 28/76 (36%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 624 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVINKTATGYGFA 682 W G R +AE LL G FLVRES+ G Y V +G+V+H I A+ Sbjct: 82 WFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHASKLSID 141 Query: 683 EPYNLYSSLKELVLHY 698 E + +L +LV HY Sbjct: 142 EEV-YFENLMQLVEHY 156 >3IUG-A nrPDB Length = 229 Score = 48.1 bits (113), Expect = 1e-05, Method: Compositional matrix adjust. Identities = 45/163 (27%), Positives = 80/163 (49%), Gaps = 9/163 (5%) Query: 117 DLAEQFAPPDIAPPLLIKLVEA-IEKKGLECSTLYRTQS-SSNLAELRQLLDCD-TPSVD 173 DL E P +++ A IE+ G+ +YR +SN+ LR D + P + Sbjct: 25 DLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSEHVPDLT 83 Query: 174 LE--MIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPS 231 E + D+H + K Y +LPNP++ +Y E S A + EE + + +I+ Sbjct: 84 KEPYVQDIHSVGSLCKLYFRELPNPLLTYQLY-EKFSDAVSAATDEERLIKIHDVIQQLP 142 Query: 232 IPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFR 274 PH + TL++L++H L+ S ++A+ L+ +++P L R Sbjct: 143 PPH--YRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLR 183 >1F7C-A nrPDB Length = 231 Score = 47.4 bits (111), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 47/195 (24%), Positives = 83/195 (42%), Gaps = 16/195 (8%) Query: 126 DIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAE--LRQLLDCDTPS-VDLEMI---DV 179 I ++ K + A+E +G+ LYR ++ + L L+D T + + E+ ++ Sbjct: 35 SIGFSIIKKCIHAVETRGINEQGLYRIVGVNSRVQKLLSILMDPKTATETETEICAEWEI 94 Query: 180 HVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLT 239 + A K YL LP P++ I A ++++ E + + L+ +P + Sbjct: 95 KTITSALKTYLRMLPGPLMMYQFQRSFIK-AAKLENQESRVSEIHSLVHR--LPEKNRQM 151 Query: 240 LQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFR-----FSAASSDNTENLIKVIEILI 294 L L+ H K++ +NL+ L +F P L R +A +N+ VIEILI Sbjct: 152 LHLLMNHLAKVADNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNI--VIEILI 209 Query: 295 STEWNERQPAPALPP 309 P PP Sbjct: 210 ENHEKIFNTVPETPP 224 >2MBG-A nrPDB Length = 265 Score = 47.0 bits (110), Expect = 3e-05, Method: Compositional matrix adjust. Identities = 43/191 (22%), Positives = 88/191 (46%), Gaps = 19/191 (9%) Query: 129 PPLLIKLVEAIEKKGLECSTLYRTQS-SSNLAELRQLLDCDTPSVDLEMIDVHVLADAFK 187 P + + ++ +EK G++C +YR S + EL+ D + S +LE + + +A K Sbjct: 29 PAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDREE-STNLEDYEPNTVASLLK 87 Query: 188 RYLLDLPNPVIPAAV---YSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLL 244 +YL DLP ++ + + E E + +E+ +LLK+L P +L + +L+ Sbjct: 88 QYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLKEL------PECNYLLISWLI 141 Query: 245 KHFFKLSQTSSKNLLNARVLSEIFSP-------MLFRFSAASSDNTENLIKVIEILISTE 297 H + + +N + +S + SP +L+ F + N++ + +++ Sbjct: 142 VHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVFFTHVQELFGNVV-LKQVMKPLR 200 Query: 298 WNERQPAPALP 308 W+ P LP Sbjct: 201 WSNMATMPTLP 211 >2EKX-A nrPDB Length = 110 Score = 46.2 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 28/90 (31%), Positives = 48/90 (53%), Gaps = 7/90 (7%) Query: 620 DEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCYACSVVV------DGEVKHCVI 672 D+ W G+ +R+++E LLR K ++G F+VR SS+ G Y S+ G VKH + Sbjct: 9 DDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHV 68 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQHTS 702 + A + + S+ +L+ ++QH S Sbjct: 69 HTNAENKLYLAENYCFDSIPKLIHYHQHNS 98 Score = 42.0 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 34/117 (29%), Positives = 63/117 (53%), Gaps = 15/117 (12%) Query: 321 GMNNNMSLQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTL-RKGGNN 378 G + + L D +W+ G+ISR + + LR +G F+VR++S G YT++L K N+ Sbjct: 1 GSSGSSGLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQV--GMYTVSLFSKAVND 58 Query: 379 K--LIKIFH----RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVS 429 K +K +H + K ++ F S+ +LI+++++ S + +L +PVS Sbjct: 59 KKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSAG-----MITRLRHPVS 110 >2LQW-A nrPDB Length = 303 Score = 45.8 bits (107), Expect = 7e-05, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVIN 673 D W +G +R +A+ L+G+R G FLVR+SS G Y SV + V H +IN Sbjct: 10 DRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIIN 64 Score = 42.7 bits (99), Expect = 6e-04, Method: Compositional matrix adjust. Identities = 19/42 (45%), Positives = 27/42 (64%), Gaps = 1/42 (2%) Query: 331 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTL 372 + WY G +SR+E +L+ G FLVRD+ST GDY L++ Sbjct: 12 SAWYMGPVSRQEAQTRLQGQRHGMFLVRDSST-CPGDYVLSV 52 >2KK6-A nrPDB Length = 116 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 6/99 (6%) Query: 621 EKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATGY 679 E+ W G+ R +A+ LL K+ G FLVRES K G Y SV DG+ +H +I Y Sbjct: 16 EQDWYHGAIPRIEAQELL--KKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMY 73 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 F +S++ +L+ H+ T V S V L P+ Sbjct: 74 RFEG--TGFSNIPQLIDHHYTTKQVITKKS-GVVLLNPI 109 Score = 43.5 bits (101), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/103 (33%), Positives = 51/103 (49%), Gaps = 5/103 (4%) Query: 328 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 L + +WY G I R E E L+ D FLVR++ K G+Y L++ G + I + D Sbjct: 14 LAEQDWYHGAIPRIEAQELLKKQGD--FLVRESHGKP-GEYVLSVYSDGQRRHFIIQYVD 70 Query: 388 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 430 Y F + FS++ +LI+H+ K V LL P+ K Sbjct: 71 NMYRF-EGTGFSNIPQLIDHHYTTKQV-ITKKSGVVLLNPIPK 111 >1GRI-A nrPDB Length = 217 Score = 45.1 bits (105), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 30/95 (31%), Positives = 58/95 (61%), Gaps = 6/95 (6%) Query: 324 NNMSLQDAEWYWGDISREEVNEKL-RDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIK 382 N + ++ W++G I R + E L + DG FL+R+ S GD++L+++ G + + K Sbjct: 51 NYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRE-SESAPGDFSLSVKFGNDVQHFK 109 Query: 383 IFHRD--GKYGFSDPLTFSSVVELINHYRNESLAQ 415 + RD GKY F + F+S+ EL++++R+ S+++ Sbjct: 110 VL-RDGAGKY-FLWVVKFNSLNELVDYHRSTSVSR 142 Score = 43.5 bits (101), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 30/82 (36%), Positives = 45/82 (54%), Gaps = 3/82 (3%) Query: 624 WNVGSSNRNKAENLLRGKR-DGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATGYGF 681 W G R KAE +L +R DG FL+RES S G ++ SV +V+H + + G F Sbjct: 60 WFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGKYF 119 Query: 682 AEPYNLYSSLKELVLHYQHTSL 703 ++SL ELV +++ TS+ Sbjct: 120 LWVVK-FNSLNELVDYHRSTSV 140 >6C7Y-B nrPDB Length = 117 Score = 44.3 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 26/84 (30%), Positives = 47/84 (55%), Gaps = 3/84 (3%) Query: 327 SLQDA-EWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH 385 SL DA +YWG ++ +EKL+ +GTFL+RD ST+ + + ++++ I+I Sbjct: 21 SLLDACGFYWGPLTVSAAHEKLKSEPEGTFLIRD-STQKNCFFAISVKTATGPTSIRINF 79 Query: 386 RDGKYGFS-DPLTFSSVVELINHY 408 + G++ TF + +L+ HY Sbjct: 80 QTGRFSLDGSKETFDCLFKLLEHY 103 >2EYZ-A nrPDB Length = 304 Score = 43.9 bits (102), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 22/50 (44%), Positives = 30/50 (60%), Gaps = 1/50 (2%) Query: 323 NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTL 372 N S + + WYWG +SR+E L+ G FLVRD+ST GDY L++ Sbjct: 3 GNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTS-PGDYVLSV 51 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 1/55 (1%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVIN 673 + +W G +R +A LL+G+R G FLVR+SS G Y SV + V H +IN Sbjct: 9 ERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIIN 63 Score = 33.1 bits (74), Expect = 0.41, Method: Compositional matrix adjust. Identities = 22/67 (32%), Positives = 30/67 (44%), Gaps = 16/67 (23%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 RAL+D+ EED+ GDIL + +PEE W ++ G+RG Sbjct: 138 RALFDFNGNDEEDLPFKKGDILRIRD--------------KPEEQWW--NAEDSEGKRGM 181 Query: 69 FPGTYVE 75 P YVE Sbjct: 182 IPVPYVE 188 >6F3F-A nrPDB Length = 455 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 34/91 (37%), Positives = 51/91 (56%), Gaps = 11/91 (12%) Query: 327 SLQDAEWYWGDISREEVNEKLRDTAD---GTFLVRDASTKMHGDYTLTLR-----KGGNN 378 S+Q EWY+G I+R E +E+L A+ GTFLVR++ T G Y L++ KG N Sbjct: 64 SIQAEEWYFGKITRRE-SERLLLNAENPRGTFLVRESETT-KGAYCLSVSDFDNAKGLNV 121 Query: 379 KLIKIFHRD-GKYGFSDPLTFSSVVELINHY 408 K KI D G + + F+S+ +L+ +Y Sbjct: 122 KHYKIRKLDSGGFYITSRTQFNSLQQLVAYY 152 >5JCP-B nrPDB Length = 419 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 46/187 (24%), Positives = 83/187 (44%), Gaps = 21/187 (11%) Query: 120 EQFAPPDIAPPLLIKLVEAIEKKGLECSTLYR-----TQSSSNLAELRQLLDCDTPSVDL 174 +Q + DI P ++ + + + GL +YR +S LAE R+ D SV L Sbjct: 16 QQMSRGDI-PIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRR----DARSVKL 70 Query: 175 EMID--VHVLADAFKRYLLDLPNPVIPAAV---YSEMISLAPEVQSSEEYIQLLKKLIRS 229 + V + D KR+ +L +PV A + + E L + Q E+Y ++ L Sbjct: 71 RPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCL--- 127 Query: 230 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKV 289 P TL L+ H +++ + ++ N + R L+ +F+P +F+ L ++ Sbjct: 128 ---PRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQEL 184 Query: 290 IEILIST 296 I+ IS Sbjct: 185 IDGYISV 191 >2H8H-A nrPDB Length = 535 Score = 43.1 bits (100), Expect = 4e-04, Method: Compositional matrix adjust. Identities = 35/101 (34%), Positives = 56/101 (55%), Gaps = 11/101 (10%) Query: 317 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTAD---GTFLVRDASTKMHGDYTLTLR 373 + +N + + S+Q EWY+G I+R E +E+L A+ GTFLVR++ T G Y L++ Sbjct: 134 IPSNYVAPSDSIQAEEWYFGKITRRE-SERLLLNAENPRGTFLVRESET-TKGAYCLSVS 191 Query: 374 -----KGGNNKLIKIFHRD-GKYGFSDPLTFSSVVELINHY 408 KG N K KI D G + + F+S+ +L+ +Y Sbjct: 192 DFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYY 232 >4FL3-A nrPDB Length = 635 Score = 43.1 bits (100), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 26/86 (30%), Positives = 44/86 (51%), Gaps = 2/86 (2%) Query: 619 HDEKTWNVGSSNRNKAEN--LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H++ W G +R ++E L+ K +G FL+R G YA ++ +G+V H I+K Sbjct: 163 HEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDK 222 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTS 702 TG + +L +LV HY + + Sbjct: 223 TGKLSIPEGKKFDTLWQLVEHYSYKA 248 >5C2K-A nrPDB Length = 415 Score = 42.4 bits (98), Expect = 8e-04, Method: Compositional matrix adjust. Identities = 42/189 (22%), Positives = 87/189 (46%), Gaps = 14/189 (7%) Query: 115 LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSS-NLAELRQ-LLDCDTPSV 172 L D Q +P + P +++ V IE++GL + LYR + EL++ L T + Sbjct: 220 LADFVSQTSP--MIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPL 277 Query: 173 DLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSI 232 ++ D+H + K +L +L P++ + + A E+ + I + + + + Sbjct: 278 LSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFME-AAEITDEDNSIAAMYQAVG--EL 334 Query: 233 PHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD------NTENL 286 P TL +L+ H +++Q S ++ L+++F P + + + D + + Sbjct: 335 PQANRDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQ 393 Query: 287 IKVIEILIS 295 KV+E L+S Sbjct: 394 PKVVERLLS 402 >1A81-A nrPDB Length = 254 Score = 42.0 bits (97), Expect = 9e-04, Method: Compositional matrix adjust. Identities = 30/102 (29%), Positives = 48/102 (47%), Gaps = 7/102 (6%) Query: 619 HDEKTWNVGSSNRNKAEN--LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H++ W G +R ++E L+ K +G FL+R G YA ++ +G+V H I+K Sbjct: 155 HEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDK 214 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 TG + +L +LV HY + + D L L P Sbjct: 215 TGKLSIPEGKKFDTLWQLVEHYSYKA-----DGLLRVLTVPC 251 >5JD0-A nrPDB Length = 211 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 46/185 (24%), Positives = 86/185 (46%), Gaps = 25/185 (13%) Query: 120 EQFAPPDIAPPLLIKLVEAIEKKGLECSTLYR-----TQSSSNLAELRQLLDCDTPSVDL 174 +Q + DI P ++ + + + GL +YR +S LAE R+ D SV L Sbjct: 16 QQMSRGDI-PIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRR----DARSVKL 70 Query: 175 EMID--VHVLADAFKRYLLDLPNPVIPAAV---YSEMISLAPEVQSSEEYIQLLKKLIRS 229 + V + D KR+ +L +PV A + + E L + Q E+Y ++ L Sbjct: 71 RPGEHFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCL--- 127 Query: 230 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKV 289 P TL L+ H +++ + ++ N + R L+ +F+P +F+ + E+ ++V Sbjct: 128 ---PRVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQ----TDGRGEHEVRV 180 Query: 290 IEILI 294 ++ LI Sbjct: 181 LQELI 185 >4H1O-A nrPDB Length = 560 Score = 40.8 bits (94), Expect = 0.002, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 53/100 (53%), Gaps = 5/100 (5%) Query: 333 WYWGDISREEV-NEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYG 391 W+ +I+ E N L DG+FL R + + GD+TL++R+ G IKI + G Y Sbjct: 27 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNP-GDFTLSVRRNGAVTHIKIQNTGGYYD 85 Query: 392 FSDPLTFSSVVELINHY--RNESLAQYNPKLDVKLLYPVS 429 F+++ EL+ +Y + L + N + ++L YP++ Sbjct: 86 LYGGEKFATLAELVQYYMEHHGQLKEKNGDV-IELKYPLN 124 Score = 37.7 bits (86), Expect = 0.018, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 12/94 (12%) Query: 333 WYWGDISREEVNEKLRDTAD-GTFLVRDASTKMHGDYTLTLRKG--------GNNKLIKI 383 W+ G +S +E + L + G+FLVR++ + GD+ L++R G G +K+ + Sbjct: 133 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHP-GDFVLSVRTGDDKGESNDGKSKVTHV 191 Query: 384 FHR--DGKYGFSDPLTFSSVVELINHYRNESLAQ 415 R + KY F S+ +L+ HY+ + + Sbjct: 192 MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE 225 >4M4Z-A nrPDB Length = 170 Score = 38.5 bits (88), Expect = 0.010, Method: Composition-based stats. Identities = 28/83 (33%), Positives = 42/83 (50%), Gaps = 8/83 (9%) Query: 624 WNVGSSNRNKAENLL--RGKRDGTFLVRES-SKQGCYACSVVVD-----GEVKHCVINKT 675 W +R KAE LL G G FL+RES +++G Y+ SV + ++H I+ Sbjct: 71 WLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRIHCL 130 Query: 676 ATGYGFAEPYNLYSSLKELVLHY 698 G+ + P + SL+ LV HY Sbjct: 131 DNGWLYISPRLTFPSLQALVDHY 153 >2QV2-A nrPDB Length = 342 Score = 38.5 bits (88), Expect = 0.010, Method: Compositional matrix adjust. Identities = 32/117 (27%), Positives = 57/117 (48%), Gaps = 12/117 (10%) Query: 160 ELRQLLDCDTPSVDLEMI--DVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSE 217 EL+Q++DC S+ E I H +A+A +L LP PVI +Y + A + + Sbjct: 205 ELQQIIDCLDTSIP-ETIPGSNHSVAEALLIFLEALPEPVICYELYQRCLDSAYDPRICR 263 Query: 218 EYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFR 274 + I L + R+ +YL+ +L + S N +NA +++ +F+ +L R Sbjct: 264 QVISQLPRCHRN---------VFRYLMAFLRELLKFSEYNSVNANMIATLFTSLLLR 311 >3PVL-A nrPDB Length = 655 Score = 38.5 bits (88), Expect = 0.011, Method: Compositional matrix adjust. Identities = 22/57 (38%), Positives = 28/57 (49%), Gaps = 3/57 (5%) Query: 29 ILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPP 85 L+ KG L+ L G++ GW NG NE T +RGDFP V Y+ PP Sbjct: 592 FLSFAKGDLIILDHDTGEQVM--NSGWANGINERTKQRGDFPTDCV-YVMPTVTLPP 645 >3WPS-A nrPDB Length = 208 Score = 38.1 bits (87), Expect = 0.015, Method: Compositional matrix adjust. Identities = 37/169 (21%), Positives = 78/169 (46%), Gaps = 8/169 (4%) Query: 115 LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSS-NLAELRQ-LLDCDTPSV 172 L D Q +P + P +++ V IE++GL + LYR + EL++ L T + Sbjct: 13 LADFVSQTSP--MIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPL 70 Query: 173 DLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSI 232 ++ D+H + K +L +L P++ + + A E+ + I + + + + Sbjct: 71 LSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFME-AAEITDEDNSIAAMYQAVG--EL 127 Query: 233 PHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD 281 P TL +L+ H +++Q S ++ L+++F P + + + D Sbjct: 128 PQANRDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPD 175 >6CMQ-A nrPDB Length = 427 Score = 37.7 bits (86), Expect = 0.016, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 47/94 (50%), Gaps = 12/94 (12%) Query: 333 WYWGDISREEVNEKLRDTAD-GTFLVRDASTKMHGDYTLTLRKG--------GNNKLIKI 383 W+ G +S +E + L + G+FLVR++ + GD+ L++R G G +K+ + Sbjct: 10 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHP-GDFVLSVRTGDDKGESNDGKSKVTHV 68 Query: 384 FHR--DGKYGFSDPLTFSSVVELINHYRNESLAQ 415 R + KY F S+ +L+ HY+ + + Sbjct: 69 MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVE 102 >6R3V-A nrPDB Length = 439 Score = 37.7 bits (86), Expect = 0.017, Method: Compositional matrix adjust. Identities = 43/202 (21%), Positives = 92/202 (45%), Gaps = 12/202 (5%) Query: 109 EQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDC 167 +Q ++L L E+ + P +L + V ++ L ++R +++ + E++Q + Sbjct: 240 QQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNM 299 Query: 168 DTPSVDLEMID-VHVLADAFKRYLLDLPNPVIPAAVYSEMISL--APEVQSSEEYIQLLK 224 P VD + + +H+ A K +L +LP P++ +Y ++ E Q +Q+L+ Sbjct: 300 GLP-VDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQ 358 Query: 225 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSP-MLFRFSAASSDNT 283 ++P + + L++L ++S S +N + L+ +F P +L+ AA + Sbjct: 359 ------TLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKA 412 Query: 284 ENLIKVIEILISTEWNERQPAP 305 N I + E P+P Sbjct: 413 INPINTFTKFLLDHQGELFPSP 434 >6C5X-D nrPDB Length = 164 Score = 37.4 bits (85), Expect = 0.024, Method: Composition-based stats. Identities = 21/77 (27%), Positives = 39/77 (50%), Gaps = 2/77 (2%) Query: 333 WYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGF 392 +YWG + ++KL+ GTFL+RD+ K + + ++++ I+I GK+ Sbjct: 32 FYWGPMDVNVAHDKLKSEPIGTFLIRDSKQK-NCFFAISVKTARETVSIRIKFHAGKFSL 90 Query: 393 S-DPLTFSSVVELINHY 408 FS + +L+ HY Sbjct: 91 DGSKELFSCLFQLVEHY 107 Score = 35.4 bits (80), Expect = 0.093, Method: Composition-based stats. Identities = 24/73 (32%), Positives = 36/73 (49%), Gaps = 1/73 (1%) Query: 627 GSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVINKTATGYGFAEPY 685 G + N A + L+ + GTFL+R+S ++ C +A SV E I A + Sbjct: 35 GPMDVNVAHDKLKSEPIGTFLIRDSKQKNCFFAISVKTARETVSIRIKFHAGKFSLDGSK 94 Query: 686 NLYSSLKELVLHY 698 L+S L +LV HY Sbjct: 95 ELFSCLFQLVEHY 107 >2IZV-A nrPDB Length = 187 Score = 37.0 bits (84), Expect = 0.034, Method: Compositional matrix adjust. Identities = 26/111 (23%), Positives = 53/111 (47%), Gaps = 8/111 (7%) Query: 326 MSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH 385 + + + YWG + + L +GTFL+RD++ + + ++++ R+ + +I Sbjct: 29 LQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYL-FSVSFRRYSRSLHARIEQ 87 Query: 386 RDGKYGFS--DPLTFSS--VVELINHYRNESLAQ-YNPKLDVKLL--YPVS 429 + + F DP F S + L+ HY++ S + P L L+ +P S Sbjct: 88 WNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLSTPLIRTFPFS 138 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 22/57 (38%), Positives = 34/57 (59%), Gaps = 3/57 (5%) Query: 598 LGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQ 654 LG EN Q LV D + +++ W G ++ AE LL GK +GTFL+R+S+++ Sbjct: 13 LGTENLYFQSMLVPDLLQI-NNNPCYW--GVMDKYAAEALLEGKPEGTFLLRDSAQE 66 >2OZO-A nrPDB Length = 613 Score = 36.6 bits (83), Expect = 0.037, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 619 HDEKTWNVGSSNRNKAENLL--RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H+ W S R +AE L + DG FL+R +QG YA S++ V H +I++ Sbjct: 158 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDK 217 Query: 677 TG 678 G Sbjct: 218 AG 219 Score = 35.0 bits (79), Expect = 0.13, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 15/85 (17%) Query: 333 WYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH----- 385 WY ++REE KL A DG FL+R K G Y L+L G ++H Sbjct: 163 WYHSSLTREEAERKLYSGAQTDGKFLLR--PRKEQGTYALSLIYGKT-----VYHYLISQ 215 Query: 386 -RDGKYGFSDPLTFSSVVELINHYR 409 + GKY + F ++ +L+ + + Sbjct: 216 DKAGKYCIPEGTKFDTLWQLVEYLK 240 >4XZ1-A nrPDB Length = 262 Score = 36.2 bits (82), Expect = 0.051, Method: Compositional matrix adjust. Identities = 21/62 (33%), Positives = 31/62 (50%), Gaps = 2/62 (3%) Query: 619 HDEKTWNVGSSNRNKAENLL--RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H+ W S R +AE L + DG FL+R +QG YA S++ V H +I++ Sbjct: 161 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDK 220 Query: 677 TG 678 G Sbjct: 221 AG 222 Score = 34.3 bits (77), Expect = 0.19, Method: Compositional matrix adjust. Identities = 25/85 (29%), Positives = 39/85 (45%), Gaps = 15/85 (17%) Query: 333 WYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH----- 385 WY ++REE KL A DG FL+R K G Y L+L G ++H Sbjct: 166 WYHSSLTREEAERKLYSGAQTDGKFLLR--PRKEQGTYALSLIYGKT-----VYHYLISQ 218 Query: 386 -RDGKYGFSDPLTFSSVVELINHYR 409 + GKY + F ++ +L+ + + Sbjct: 219 DKAGKYCIPEGTKFDTLWQLVEYLK 243 >1OW3-A nrPDB Length = 242 Score = 36.2 bits (82), Expect = 0.055, Method: Compositional matrix adjust. Identities = 43/202 (21%), Positives = 92/202 (45%), Gaps = 12/202 (5%) Query: 109 EQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDC 167 +Q ++L L E+ + P +L + V ++ L ++R +++ + E++Q + Sbjct: 43 QQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNM 102 Query: 168 DTPSVDLEMID-VHVLADAFKRYLLDLPNPVIPAAVYSEMISL--APEVQSSEEYIQLLK 224 P VD + + +H+ A K +L +LP P++ +Y ++ E Q +Q+L+ Sbjct: 103 GLP-VDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQ 161 Query: 225 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSP-MLFRFSAASSDNT 283 ++P + + L++L ++S S +N + L+ +F P +L+ AA + Sbjct: 162 ------TLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKA 215 Query: 284 ENLIKVIEILISTEWNERQPAP 305 N I + E P+P Sbjct: 216 INPINTFTKFLLDHQGELFPSP 237 >3EAP-A nrPDB Length = 271 Score = 35.4 bits (80), Expect = 0.086, Method: Compositional matrix adjust. Identities = 27/118 (22%), Positives = 54/118 (45%), Gaps = 7/118 (5%) Query: 182 LADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQ 241 +A K++ +LP P++PA ++ ++ + LL + + H L+ Sbjct: 135 IAGLLKQFFRELPEPILPADLHEALLKAQQLGTEEKNKATLLLSCLLADHTVH----VLR 190 Query: 242 YLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAAS---SDNTENLIKVIEILIST 296 Y +S SS+N +++ L+ IF+P L + S S NTE +++ ++ T Sbjct: 191 YFFNFLRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEKKLRLQAAVVQT 248 >1GRN-B nrPDB Length = 203 Score = 35.4 bits (80), Expect = 0.089, Method: Compositional matrix adjust. Identities = 40/182 (21%), Positives = 82/182 (45%), Gaps = 12/182 (6%) Query: 129 PPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDCDTPSVDLEMID-VHVLADAF 186 P +L + V ++ L ++R +++ + E++Q + P VD + + +H+ A Sbjct: 24 PIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNMGLP-VDFDQYNELHLPAVIL 82 Query: 187 KRYLLDLPNPVIPAAVYSEMISL--APEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLL 244 K +L +LP P++ +Y ++ E Q +Q+L+ L P + + L++L Sbjct: 83 KTFLRELPEPLLTFDLYPHVVGFLNIDESQRVPATLQVLQTL------PEENYQVLRFLT 136 Query: 245 KHFFKLSQTSSKNLLNARVLSEIFSP-MLFRFSAASSDNTENLIKVIEILISTEWNERQP 303 ++S S +N + L+ +F P +L+ AA + N I + E P Sbjct: 137 AFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINPINTFTKFLLDHQGELFP 196 Query: 304 AP 305 +P Sbjct: 197 SP 198 >2CUC-A nrPDB Length = 70 Score = 35.4 bits (80), Expect = 0.10, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 31/72 (43%), Gaps = 15/72 (20%) Query: 3 AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNET 62 + G + AL+ Y R E++DL G+ G V + DG WL G + Sbjct: 5 SSGNMFVALHTYSAHRPEELDLQKGE------GIRVLGKYQDG---------WLKGLSLL 49 Query: 63 TGERGDFPGTYV 74 TG G FP YV Sbjct: 50 TGRTGIFPSDYV 61 >3PS5-A nrPDB Length = 595 Score = 35.0 bits (79), Expect = 0.11, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Query: 333 WYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYG 391 W+ D+S + L+ G+FL R S K GD++L++R G I+I + Y Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLAR-PSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 392 FSDPLTFSSVVELINHY-RNESLAQYNPKLDVKLLYPVS 429 F+++ EL+ +Y + + + Q + L YP++ Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLN 101 Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 11/91 (12%) Query: 333 WYWGDISREEVNEKLRDTAD-GTFLVRDASTKMHGDYTLTL-----RKGGNNKL----IK 382 WY G +S + L+ + TFLVR+ S GD+ L++ + G + L IK Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRE-SLSQPGDFVLSVLSDQPKAGPGSPLRVTHIK 168 Query: 383 IFHRDGKYGFSDPLTFSSVVELINHYRNESL 413 + G+Y TF S+ +L+ H++ + Sbjct: 169 VMCEGGRYTVGGLETFDSLTDLVEHFKKTGI 199 >2B3O-A nrPDB Length = 532 Score = 35.0 bits (79), Expect = 0.12, Method: Compositional matrix adjust. Identities = 26/99 (26%), Positives = 48/99 (48%), Gaps = 3/99 (3%) Query: 333 WYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYG 391 W+ D+S + L+ G+FL R S K GD++L++R G I+I + Y Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLAR-PSRKNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 392 FSDPLTFSSVVELINHY-RNESLAQYNPKLDVKLLYPVS 429 F+++ EL+ +Y + + + Q + L YP++ Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPLN 101 Score = 34.7 bits (78), Expect = 0.16, Method: Compositional matrix adjust. Identities = 25/91 (27%), Positives = 43/91 (47%), Gaps = 11/91 (12%) Query: 333 WYWGDISREEVNEKLRDTAD-GTFLVRDASTKMHGDYTLTL-----RKGGNNKL----IK 382 WY G +S + L+ + TFLVR+ S GD+ L++ + G + L IK Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRE-SLSQPGDFVLSVLSDQPKAGPGSPLRVTHIK 168 Query: 383 IFHRDGKYGFSDPLTFSSVVELINHYRNESL 413 + G+Y TF S+ +L+ H++ + Sbjct: 169 VMCEGGRYTVGGLETFDSLTDLVEHFKKTGI 199 >4N78-F nrPDB Length = 514 Score = 35.0 bits (79), Expect = 0.13, Method: Compositional matrix adjust. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 17/68 (25%) Query: 10 ALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDF 69 A+YDY K++E+++ G I+ V K + + GW G G G F Sbjct: 459 AIYDYTKDKEDELSFQEGAIIYVIKKN---------------DDGWYEGV--MNGVTGLF 501 Query: 70 PGTYVEYI 77 PG YVE I Sbjct: 502 PGNYVESI 509 >4C7Y-A nrPDB Length = 907 Score = 34.7 bits (78), Expect = 0.15, Method: Compositional matrix adjust. Identities = 23/60 (38%), Positives = 33/60 (55%), Gaps = 10/60 (16%) Query: 648 VRESSKQG-CYACSVVVDGE-VKHCV--INKTATGY------GFAEPYNLYSSLKELVLH 697 V+ +QG C ACSV++DG+ V+ CV + + A G G +P NL+ K VLH Sbjct: 36 VKVGCEQGQCGACSVILDGKVVRACVTKMKRVADGAQITTIEGVGQPENLHPLQKAWVLH 95 >2X3W-D nrPDB Length = 60 Score = 34.3 bits (77), Expect = 0.21, Method: Compositional matrix adjust. Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 15/75 (20%) Query: 3 AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNET 62 A+G + RALYDY + ++++ GD LT LG D E GW G + Sbjct: 1 AKGVRVRALYDYDGQEQDELSFKAGDELT-------KLGEED-------EQGWCRGRLD- 45 Query: 63 TGERGDFPGTYVEYI 77 +G+ G +P YVE I Sbjct: 46 SGQLGLYPANYVEAI 60 >6F55-A nrPDB Length = 67 Score = 33.9 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 15/78 (19%) Query: 1 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN 60 M G + RALYDY + +++ G+ L + + +E GW G Sbjct: 1 MKVPGVRVRALYDYTGQEADELSFKAGEELM--------------KISEEDEQGWCKG-R 45 Query: 61 ETTGERGDFPGTYVEYIG 78 TG G +P YVE +G Sbjct: 46 LLTGHVGLYPANYVEKVG 63 >2ED0-A nrPDB Length = 78 Score = 33.5 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 17/68 (25%) Query: 10 ALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDF 69 A+YDY K++E+++ G I+ V K + + GW G G G F Sbjct: 22 AIYDYTKDKEDELSFQEGAIIYVIKKN---------------DDGWYEGV--MNGVTGLF 64 Query: 70 PGTYVEYI 77 PG YVE I Sbjct: 65 PGNYVESI 72 >3KUQ-A nrPDB Length = 228 Score = 33.1 bits (74), Expect = 0.40, Method: Compositional matrix adjust. Identities = 29/128 (22%), Positives = 56/128 (43%), Gaps = 3/128 (2%) Query: 156 SNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQS 215 S + LRQ+ + V+ E + +AD K+Y DLP P++ + + + V Sbjct: 65 SRIQALRQMNEGAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYV-P 123 Query: 216 SEEYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRF 275 ++ +Q +K I +P + LQ LL ++ +N + L+ +P LF Sbjct: 124 KDQRLQAIKAAIM--LLPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHL 181 Query: 276 SAASSDNT 283 + +N+ Sbjct: 182 NTLKRENS 189 >4E93-A nrPDB Length = 377 Score = 32.7 bits (73), Expect = 0.50, Method: Compositional matrix adjust. Identities = 22/57 (38%), Positives = 29/57 (50%), Gaps = 3/57 (5%) Query: 617 PHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVIN 673 P H E+ W G+ R + LL G FLVRES + Y SV+ DG +H +I Sbjct: 9 PLH-EQLWYHGAIPRAEVAELL--VHSGDFLVRESQGKQEYVLSVLWDGLPRHFIIQ 62 >1Y1U-A nrPDB Length = 585 Score = 32.0 bits (71), Expect = 0.86, Method: Compositional matrix adjust. Identities = 18/42 (42%), Positives = 24/42 (57%), Gaps = 4/42 (9%) Query: 614 EDLPHHDEKTWN----VGSSNRNKAENLLRGKRDGTFLVRES 651 E L H + WN +G N+ +A +LL K DGTFL+R S Sbjct: 452 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFS 493 >4BNE-A nrPDB Length = 457 Score = 32.0 bits (71), Expect = 0.92, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 15/69 (21%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 RALYDY+ + ++++ GD LT + +E GW G + G+ G Sbjct: 403 RALYDYEGQEQDELSFKAGDELT--------------KMENEDEQGWCKGRLD-NGQVGL 447 Query: 69 FPGTYVEYI 77 +P YVE I Sbjct: 448 YPANYVEPI 456 >2ZR2-A nrPDB Length = 455 Score = 32.0 bits (71), Expect = 1.0, Method: Compositional matrix adjust. Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 4/63 (6%) Query: 519 KEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRD 578 KEI R+ H +K+ I + RR+ E + + A+ REI KR+ ++ ++ +L+K D Sbjct: 45 KEINRLRHERNKIAVEIGK----RRKKGEPVDELLAKSREIVKRIGELENEVEELKKKID 100 Query: 579 QYL 581 YL Sbjct: 101 YYL 103 >3HAJ-A nrPDB Length = 486 Score = 31.6 bits (70), Expect = 1.1, Method: Compositional matrix adjust. Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 15/69 (21%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 RALYDY+ + +++ GD LT + +E GW G + G+ G Sbjct: 432 RALYDYEGQEHDELSFKAGDELTKMEDE--------------DEQGWCKGRLD-NGQVGL 476 Query: 69 FPGTYVEYI 77 +P YVE I Sbjct: 477 YPANYVEAI 485 >1BF5-A nrPDB Length = 575 Score = 31.6 bits (70), Expect = 1.2, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 44/92 (47%), Gaps = 2/92 (2%) Query: 336 GDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDP 395 G IS+E L+D GTFL+R + + G T T + N FH Y + Sbjct: 445 GFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYTKKE- 503 Query: 396 LTFSSVVELINHYRNESLAQYNPKLDVKLLYP 427 L+ + ++I +Y+ + A+ P+ +K LYP Sbjct: 504 LSAVTFPDIIRNYKVMA-AENIPENPLKYLYP 534 >1K4U-S nrPDB Length = 62 Score = 31.6 bits (70), Expect = 1.3, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 32/71 (45%), Gaps = 17/71 (23%) Query: 5 GYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTG 64 G Q AL+ Y+ + ED++ GDI+ V S E WL G E+ G Sbjct: 5 GSQVEALFSYEATQPEDLEFQEGDIILV---------LSKVNEE------WLEG--ESKG 47 Query: 65 ERGDFPGTYVE 75 + G FP +VE Sbjct: 48 KVGIFPKVFVE 58 >2CS0-A nrPDB Length = 119 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 16/42 (38%), Positives = 24/42 (57%), Gaps = 2/42 (4%) Query: 332 EWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLR 373 EW+ G ISRE+ L G+FL+R + + H YTL+ + Sbjct: 17 EWFHGAISREDAENLLESQPLGSFLIRVSHS--HVGYTLSYK 56 Score = 29.3 bits (64), Expect = 6.8, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 35/82 (42%), Gaps = 3/82 (3%) Query: 624 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFAE 683 W G+ +R AENLL + G+FL+R S Y S H ++ G F Sbjct: 18 WFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDG-TFMI 76 Query: 684 PYN--LYSSLKELVLHYQHTSL 703 P ++SL LV +Q + Sbjct: 77 PGEKVAHTSLDALVTFHQQKPI 98 >2CR4-A nrPDB Length = 126 Score = 31.2 bits (69), Expect = 1.6, Method: Compositional matrix adjust. Identities = 20/71 (28%), Positives = 34/71 (47%), Gaps = 4/71 (5%) Query: 352 DGTFLVRDASTKMHGDYTLTLRKGGNNKL--IKIFHRDGKYGFSDPLTFSSVVELINHYR 409 DG + +R++STK L + +NK+ +IF +D K+ + F SV ++ HY Sbjct: 44 DGLYCIRNSSTK--SGKVLVVWDETSNKVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYH 101 Query: 410 NESLAQYNPKL 420 L + L Sbjct: 102 THVLPSHQSLL 112 >1YVL-A nrPDB Length = 683 Score = 31.2 bits (69), Expect = 1.8, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 2/92 (2%) Query: 336 GDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDP 395 G IS+E L+D GTFL+R + + G T T + N FH Y Sbjct: 580 GFISKERERALLKDQQPGTFLLRFSESSREGAITFTWVERSQNGGEPDFHAVEPYT-KKE 638 Query: 396 LTFSSVVELINHYRNESLAQYNPKLDVKLLYP 427 L+ + ++I +Y+ + A+ P+ +K LYP Sbjct: 639 LSAVTFPDIIRNYKVMA-AENIPENPLKYLYP 669 >1SPK-A nrPDB Length = 72 Score = 30.4 bits (67), Expect = 2.9, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Query: 50 PEEI-GWLNGYNETTGERGDFPGTYVEYI 77 PEE GWL G ++TT RG FP +Y + + Sbjct: 38 PEEKDGWLYGEHDTTKARGWFPSSYTKLL 66 >1WXU-A nrPDB Length = 93 Score = 30.4 bits (67), Expect = 3.2, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 16/75 (21%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGY--NETTGER 66 RA YD+ +E+I GD+L +AL +E +P+ GWL +TTG Sbjct: 21 RAEYDFVAVSDEEISFRAGDMLN------LAL-----KEQQPKVRGWLLASLDGQTTGL- 68 Query: 67 GDFPGTYVEYIGRKK 81 P YV+ +G+++ Sbjct: 69 --IPANYVKILGKRR 81 >5U06-A nrPDB Length = 120 Score = 29.3 bits (64), Expect = 5.6, Method: Composition-based stats. Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 5/58 (8%) Query: 619 HDEKTWNVGSSNRNKAENLL--RGKRDGTFLVRESSK--QGCYACSVVVDGEVKHCVI 672 H + W G +R +++ L+ +G DG FLVRES + QG + S+ +VKH +I Sbjct: 14 HRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQG-FVLSLCHLQKVKHYLI 70 >6E11-1 nrPDB Length = 906 Score = 28.9 bits (63), Expect = 7.3, Method: Compositional matrix adjust. Identities = 25/107 (23%), Positives = 53/107 (49%), Gaps = 5/107 (4%) Query: 430 KYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQM-----KRTAI 484 ++ +D+ + + I+ + K Q K R D + R S EI + + Sbjct: 408 RFIKDRYLPDKAIDLLNKACSFLQVQLSGKPRIIDVTERDIERLSYEISTLEKDVDKVSK 467 Query: 485 EAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKL 531 + +N+ IK FEE+ + ++Y +EY+ +R +KEI++ +++ +L Sbjct: 468 KKYNKLIKEFEEKKEQLKKYYEEYVITGERLKRKKEIEKKLNDLKEL 514 >5OFO-C nrPDB Length = 871 Score = 28.9 bits (63), Expect = 9.2, Method: Compositional matrix adjust. Identities = 23/70 (32%), Positives = 36/70 (51%), Gaps = 2/70 (2%) Query: 430 KYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNE 489 K +Q ++KE + EA K+L N + +K R+Y L EE+ + +T I+A E Sbjct: 427 KLEQQALMKESD-EASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQT-IKAELE 484 Query: 490 TIKIFEEQCQ 499 KI EQ + Sbjct: 485 QAKIAIEQAR 494 >2M7L-A nrPDB Length = 144 Score = 28.5 bits (62), Expect = 9.7, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Query: 37 LVALGFSDGQEARPEEIGWLNGYNETT-GERGDFPGTYVEYIGRKKISPPTPKPRPPRPL 95 L+ + F+ G++A+ + I YN T GE G YV+Y+ K P+P+ Sbjct: 43 LIDIDFTGGEDAQYDAI-----YNNVTKGENGVSFDNYVQYMKEKNDENPSPEQLNEIFS 97 Query: 96 PVAPGS-SKTEADVEQQALT 114 +A G S TE D+++ ++ Sbjct: 98 TIAAGKDSITETDMQKAGMS 117 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 5M6U-B nrPDB 1179 0.0 1PBW-A nrPDB 293 2e-79 6MRP-B nrPDB 258 6e-69 6D81-A nrPDB 253 3e-67 3FK2-A nrPDB 206 3e-53 5IRC-A nrPDB 201 1e-51 2OSA-A nrPDB 194 8e-50 3CXL-A nrPDB 192 5e-49 1XA6-A nrPDB 191 8e-49 2EE4-A nrPDB 189 3e-48 5MY3-A nrPDB 182 4e-46 3BYI-A nrPDB 179 4e-45 5C5S-A nrPDB 174 1e-43 1F7C-A nrPDB 174 1e-43 5C2K-A nrPDB 172 7e-43 2FO0-A nrPDB 171 1e-42 6AMW-A nrPDB 168 6e-42 5JD0-A nrPDB 166 4e-41 6GVC-R nrPDB 166 4e-41 5JCP-B nrPDB 166 5e-41 2MBG-A nrPDB 162 5e-40 2ABL-A nrPDB 161 8e-40 3IUG-A nrPDB 159 5e-39 2XS6-A nrPDB 156 5e-38 3T04-A nrPDB 138 1e-32 4XEY-B nrPDB 135 7e-32 2CRH-A nrPDB 132 6e-31 2LCT-A nrPDB 127 1e-29 1A81-A nrPDB 127 2e-29 4FL3-A nrPDB 127 2e-29 1K9A-A nrPDB 124 1e-28 4XI2-A nrPDB 120 3e-27 2VIF-A nrPDB 117 2e-26 2EKX-A nrPDB 117 3e-26 2EOB-A nrPDB 113 3e-25 2PLE-A nrPDB 112 4e-25 2KK6-A nrPDB 109 5e-24 6F3F-A nrPDB 108 8e-24 2H8H-A nrPDB 108 9e-24 1AD5-A nrPDB 104 1e-22 1GRI-A nrPDB 103 4e-22 6C7Y-B nrPDB 99 9e-21 4JGH-A nrPDB 99 9e-21 4GL9-E nrPDB 97 4e-20 2HMH-A nrPDB 96 7e-20 2BBU-A nrPDB 94 2e-19 2LQW-A nrPDB 89 5e-18 2EYZ-A nrPDB 84 2e-16 Sequences not found previously or not previously below threshold: 3WPS-A nrPDB 171 1e-42 1GRN-B nrPDB 105 8e-23 1OW3-A nrPDB 104 1e-22 6R3V-A nrPDB 104 2e-22 3KUQ-A nrPDB 100 2e-21 4XZ1-A nrPDB 97 3e-20 2OZO-A nrPDB 96 4e-20 3EAP-A nrPDB 94 3e-19 3MSX-B nrPDB 91 1e-18 6C5X-D nrPDB 88 2e-17 4H1O-A nrPDB 78 2e-14 4E93-A nrPDB 77 2e-14 6CMQ-A nrPDB 77 2e-14 2B3O-A nrPDB 76 6e-14 4M4Z-A nrPDB 75 1e-13 3PS5-A nrPDB 74 2e-13 1MIL-A nrPDB 73 4e-13 2AUG-A nrPDB 73 5e-13 5U06-A nrPDB 72 1e-12 2QV2-A nrPDB 69 7e-12 1NRV-A nrPDB 66 5e-11 2CS0-A nrPDB 66 7e-11 2IZV-A nrPDB 64 2e-10 1RPY-A nrPDB 62 1e-09 1KA6-A nrPDB 62 1e-09 1M27-A nrPDB 61 1e-09 2HDV-A nrPDB 61 2e-09 5NP2-A nrPDB 50 4e-06 3QWY-A nrPDB 49 5e-06 2CR4-A nrPDB 48 1e-05 6E11-1 nrPDB 42 0.001 2X3W-D nrPDB 40 0.003 1UUS-A nrPDB 39 0.005 3PVL-A nrPDB 39 0.007 3PJP-A nrPDB 39 0.011 5VKO-A nrPDB 38 0.013 3GXW-A nrPDB 38 0.019 3QOF-A nrPDB 37 0.027 2CUC-A nrPDB 37 0.033 6F55-A nrPDB 37 0.039 4RM9-A nrPDB 36 0.047 2ED0-A nrPDB 36 0.050 2ZR2-A nrPDB 35 0.078 5XG2-A nrPDB 35 0.095 2XPY-A nrPDB 35 0.095 6GYM-3 nrPDB 35 0.11 4N78-F nrPDB 35 0.14 1F5N-A nrPDB 35 0.14 5OFO-C nrPDB 34 0.27 1Y1U-A nrPDB 34 0.31 2I1J-A nrPDB 34 0.32 3EF1-A nrPDB 33 0.39 1WXU-A nrPDB 33 0.45 2M7L-A nrPDB 33 0.54 3KZ4-A nrPDB 33 0.56 1K4U-S nrPDB 33 0.56 5YHJ-A nrPDB 33 0.61 4U5I-A nrPDB 33 0.61 2EFL-A nrPDB 32 0.65 4BNE-A nrPDB 32 0.74 5ZWN-S nrPDB 32 0.86 5FM1-B nrPDB 32 0.89 1SPK-A nrPDB 32 0.90 4E68-A nrPDB 32 1.0 6OJ5-A nrPDB 32 1.2 3HAJ-A nrPDB 32 1.2 5AEM-A nrPDB 32 1.3 2EQI-A nrPDB 31 1.7 5XQL-A nrPDB 31 1.8 4CIU-A nrPDB 31 2.1 6MSD-E nrPDB 31 2.2 3NL2-A nrPDB 31 2.3 4V3P-LC nrPDB 31 2.4 1BF5-A nrPDB 30 2.5 1YVL-A nrPDB 30 2.7 3JA6-G nrPDB 30 2.8 3S9G-A nrPDB 30 3.0 3B98-A nrPDB 30 3.1 3AKZ-B nrPDB 30 3.2 4TKO-B nrPDB 30 3.3 3AL0-C nrPDB 30 3.7 3W4R-A nrPDB 30 3.8 3JAX-A nrPDB 30 4.4 6FSW-A nrPDB 30 4.5 6FYX-o nrPDB 30 4.6 2DLM-A nrPDB 30 5.0 1XDV-A nrPDB 30 5.2 5J1I-A nrPDB 29 5.5 5OQL-o nrPDB 29 6.6 5OVF-A nrPDB 29 7.0 1XAD-A nrPDB 29 7.6 1IDM-A nrPDB 29 7.6 4KMA-A nrPDB 29 8.0 2P22-C nrPDB 29 8.1 2PZ9-A nrPDB 29 8.5 6HIY-Cj nrPDB 29 8.6 1PWU-A nrPDB 29 9.8 >5M6U-B nrPDB Length = 724 Score = 1179 bits (3051), Expect = 0.0, Method: Composition-based stats. Identities = 720/724 (99%), Positives = 723/724 (99%) Query: 1 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN 60 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN Sbjct: 1 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN 60 Query: 61 ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE 120 ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE Sbjct: 61 ETTGERGDFPGTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLPDLAE 120 Query: 121 QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH 180 QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH Sbjct: 121 QFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVH 180 Query: 181 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL 240 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL Sbjct: 181 VLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTL 240 Query: 241 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE 300 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE Sbjct: 241 QYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNE 300 Query: 301 RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA 360 RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA Sbjct: 301 RQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDA 360 Query: 361 STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL 420 STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL Sbjct: 361 STKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKL 420 Query: 421 DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMK 480 DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYE+YTRTSQEIQMK Sbjct: 421 DVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEDYTRTSQEIQMK 480 Query: 481 RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIID 540 RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNE EIQRIMHNY+KLKSRISEI+D Sbjct: 481 RTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNETEIQRIMHNYEKLKSRISEIVD 540 Query: 541 SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN 600 SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN Sbjct: 541 SRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGN 600 Query: 601 ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS 660 ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS Sbjct: 601 ENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACS 660 Query: 661 VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA Sbjct: 661 VVVDGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 Query: 721 QQRR 724 QQRR Sbjct: 721 QQRR 724 >1PBW-A nrPDB Length = 216 Score = 293 bits (750), Expect = 2e-79, Method: Composition-based stats. Identities = 215/215 (100%), Positives = 215/215 (100%) Query: 105 EADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL 164 EADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL Sbjct: 2 EADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQL 61 Query: 165 LDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLK 224 LDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLK Sbjct: 62 LDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLK 121 Query: 225 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTE 284 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTE Sbjct: 122 KLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTE 181 Query: 285 NLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN 319 NLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN Sbjct: 182 NLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN 216 >6MRP-B nrPDB Length = 220 Score = 258 bits (659), Expect = 6e-69, Method: Composition-based stats. Identities = 197/216 (91%), Positives = 206/216 (95%), Gaps = 1/216 (0%) Query: 104 TEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQ 163 TEAD +Q A TLPDLAEQFAPPD+APPLLIKLVEAIEKKGLECSTLYRTQSSSN AELRQ Sbjct: 6 TEADSQQ-ASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQ 64 Query: 164 LLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLL 223 LLDCDT S+DLEM DVHVLADAFKRYLLDLPNPVIP AV SE+ISLAPEVQSSEEYIQLL Sbjct: 65 LLDCDTASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLL 124 Query: 224 KKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNT 283 KKLI SPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSE+FSP+LFRF AASS+NT Sbjct: 125 KKLIESPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENT 184 Query: 284 ENLIKVIEILISTEWNERQPAPALPPKPPKPTTVAN 319 E+LIK+IEILISTEWNERQPAPALPPKPPKPTTVAN Sbjct: 185 EHLIKIIEILISTEWNERQPAPALPPKPPKPTTVAN 220 >6D81-A nrPDB Length = 193 Score = 253 bits (645), Expect = 3e-67, Method: Composition-based stats. Identities = 178/193 (92%), Positives = 186/193 (96%) Query: 110 QQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDCDT 169 QQA TLPDLAEQFAPPD+APPLLIKLVEAIEKKGLECSTLYRTQSSSN AELRQLLDCDT Sbjct: 1 QQASTLPDLAEQFAPPDVAPPLLIKLVEAIEKKGLECSTLYRTQSSSNPAELRQLLDCDT 60 Query: 170 PSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRS 229 S+DLEM DVHVLADAFKRYLLDLPNPVIP AV SE+ISLAPEVQSSEEYIQLLKKLIRS Sbjct: 61 ASLDLEMFDVHVLADAFKRYLLDLPNPVIPVAVSSELISLAPEVQSSEEYIQLLKKLIRS 120 Query: 230 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKV 289 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSE+FSP+LFRF AASS+NTE+LIK+ Sbjct: 121 PSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSELFSPLLFRFPAASSENTEHLIKI 180 Query: 290 IEILISTEWNERQ 302 IEILISTEWNERQ Sbjct: 181 IEILISTEWNERQ 193 >3FK2-A nrPDB Length = 246 Score = 206 bits (524), Expect = 3e-53, Method: Composition-based stats. Identities = 52/199 (26%), Positives = 95/199 (47%), Gaps = 11/199 (5%) Query: 102 SKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAE 160 S T+A E +P L P P + + +E IE GL +YR + S + Sbjct: 43 SITKATWESNYFGVP-LTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMES 101 Query: 161 LRQLLDCDTPSVDLEMID--VHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEE 218 L++ D D ++DL D V+ +A A K + +LP+P++P + +++ A ++ E+ Sbjct: 102 LQRQFDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYNMQIDLVE-AHKINDREQ 159 Query: 219 YIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAA 278 + LK++++ P + +Y++ H K+S + NL+ + LS F P L R + Sbjct: 160 KLHALKEVLKK--FPKENHEVFKYVISHLNKVSHNNKVNLMTSENLSICFWPTLMRPDFS 217 Query: 279 SSD---NTENLIKVIEILI 294 + D T +IE+ I Sbjct: 218 TMDALTATRTYQTIIELFI 236 >5IRC-A nrPDB Length = 201 Score = 201 bits (510), Expect = 1e-51, Method: Composition-based stats. Identities = 49/195 (25%), Positives = 93/195 (47%), Gaps = 11/195 (5%) Query: 106 ADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAELRQL 164 E +P L P P + + +E IE GL +YR + S + L++ Sbjct: 2 GSWESNYFGVP-LTTVVTPEKPIPIFIERCIEYIEATGLSTEGIYRVSGNKSEMESLQRQ 60 Query: 165 LDCDTPSVDLEMID--VHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQL 222 D D ++DL D V+ +A A K + +LP+P++P ++ +++ A ++ E+ + Sbjct: 61 FDQDH-NLDLAEKDFTVNTVAGAMKSFFSELPDPLVPYSMQIDLVE-AHKINDREQKLHA 118 Query: 223 LKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD- 281 LK++++ P + +Y++ H ++S + NL+ + LS F P L R +S D Sbjct: 119 LKEVLKK--FPKENHEVFKYVISHLNRVSHNNKVNLMTSENLSICFWPTLMRPDFSSMDA 176 Query: 282 --NTENLIKVIEILI 294 T + +IE+ I Sbjct: 177 LTATRSYQTIIELFI 191 >2OSA-A nrPDB Length = 202 Score = 194 bits (494), Expect = 8e-50, Method: Composition-based stats. Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 12/194 (6%) Query: 117 DLAEQFAPPDIAPPLLIK-LVEAIEKKGLECSTLYRTQSSSNLAE-LRQLLDCDTPSVDL 174 DL P+++ + IE +GL LYR S+L E ++ D D D+ Sbjct: 12 DLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADI 71 Query: 175 EM---IDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPS 231 + D++++ A K Y DLP P+I Y + I A ++ +E ++ L + ++ Sbjct: 72 SVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESA-KIMDPDEQLETLHEALKL-- 128 Query: 232 IPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK--- 288 +P + TL+YL+ H +++ +NL+NA L +F P L R + N I+ Sbjct: 129 LPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQR 188 Query: 289 -VIEILISTEWNER 301 V+E+LI E Sbjct: 189 LVVELLIKNEDILF 202 >3CXL-A nrPDB Length = 463 Score = 192 bits (488), Expect = 5e-49, Method: Composition-based stats. Identities = 52/194 (26%), Positives = 90/194 (46%), Gaps = 12/194 (6%) Query: 117 DLAEQFAPPDIAPPLLIK-LVEAIEKKGLECSTLYRTQSSSNLAE-LRQLLDCDTPSVDL 174 DL P+++ + IE +GL LYR S+L E ++ D D D+ Sbjct: 273 DLTTLVKAHTTKRPMVVDMCIREIESRGLNSEGLYRVSGFSDLIEDVKMAFDRDGEKADI 332 Query: 175 EM---IDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPS 231 + D++++ A K Y DLP P+I Y + I A ++ +E ++ L + ++ Sbjct: 333 SVNMYEDINIITGALKLYFRDLPIPLITYDAYPKFIESA-KIMDPDEQLETLHEALKL-- 389 Query: 232 IPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK--- 288 +P + TL+YL+ H +++ +NL+NA L +F P L R + N I+ Sbjct: 390 LPPAHCETLRYLMAHLKRVTLHEKENLMNAENLGIVFGPTLMRSPELDAMAALNDIRYQR 449 Query: 289 -VIEILISTEWNER 301 V+E+LI E Sbjct: 450 LVVELLIKNEDILF 463 Score = 60.1 bits (144), Expect = 3e-09, Method: Composition-based stats. Identities = 41/168 (24%), Positives = 76/168 (45%), Gaps = 18/168 (10%) Query: 334 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS 393 + G ISRE ++ L A+G++L+R++ + G YTL LR G + ++++ DGK+ Sbjct: 54 FHGMISREAADQLLI-VAEGSYLIRES-QRQPGTYTLALRFGSQTRNFRLYY-DGKHFVG 110 Query: 394 DPLTFSSVVELINH-----YRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK 448 + F S+ +L+ Y A+Y K+ + P+ ++ + N E KK Sbjct: 111 EK-RFESIHDLVTDGLITLYIETKAAEYIAKMTI---NPIYEHVGYTTL---NREPAYKK 163 Query: 449 LHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEE 496 + +E E D ++ + + R A NE I +E+ Sbjct: 164 ---HMPVLKETHDERDSTGQDGVSEKRLTSLVRRATLKENEQIPKYEK 208 Score = 52.0 bits (123), Expect = 8e-07, Method: Composition-based stats. Identities = 15/72 (20%), Positives = 32/72 (44%), Gaps = 5/72 (6%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESS-KQGCYACSVVVDGEVKHCVINKTATGYGFAE 683 G +R A+ LL +G++L+RES + G Y ++ + ++ + + Sbjct: 54 FHGMISREAADQLLIV-AEGSYLIRESQRQPGTYTLALRFGSQTRNFRLYYDGKHFV--- 109 Query: 684 PYNLYSSLKELV 695 + S+ +LV Sbjct: 110 GEKRFESIHDLV 121 >1XA6-A nrPDB Length = 466 Score = 191 bits (486), Expect = 8e-49, Method: Composition-based stats. Identities = 49/194 (25%), Positives = 95/194 (48%), Gaps = 12/194 (6%) Query: 117 DLAEQFAPPDIAPPLLIK-LVEAIEKKGLECSTLYRTQS-SSNLAELRQLLDCDTPSVDL 174 DL + P+++ + IE +GL+ LYR + ++ +++ D D D+ Sbjct: 276 DLTTLVKAHNTQRPMVVDICIREIEARGLKSEGLYRVSGFTEHIEDVKMAFDRDGEKADI 335 Query: 175 EM---IDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPS 231 D++++ A K Y DLP PVI YS+ I A ++ +++E ++ + +++ Sbjct: 336 SANVYPDINIITGALKLYFRDLPIPVITYDTYSKFID-AAKISNADERLEAVHEVLML-- 392 Query: 232 IPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK--- 288 +P ++ TL+YL+ H K++ N +NA L +F P L R S+ T + ++ Sbjct: 393 LPPAHYETLRYLMIHLKKVTMNEKDNFMNAENLGIVFGPTLMRPPEDSTLTTLHDMRYQK 452 Query: 289 -VIEILISTEWNER 301 +++ILI E Sbjct: 453 LIVQILIENEDVLF 466 Score = 57.8 bits (138), Expect = 1e-08, Method: Composition-based stats. Identities = 39/161 (24%), Positives = 75/161 (46%), Gaps = 19/161 (11%) Query: 334 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS 393 + G ISRE+ +E L +G +++R++ + G YTL LR G ++FH DGK+ Sbjct: 58 FHGIISREQADELL-GGVEGAYILRES-QRQPGCYTLALRFGNQTLNYRLFH-DGKHFVG 114 Query: 394 DPLTFSSVVELINH-----YRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKK 448 + F S+ +L+ Y A+Y K+ P+ ++ + E V ++ Sbjct: 115 EK-RFESIHDLVTDGLITLYIETKAAEYISKMTT---NPIYEHIGYATLLR---EKVSRR 167 Query: 449 LHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNE 489 L ++ + + R+ + +EE+T + + R A N+ Sbjct: 168 L----SRSKNEPRKTNVTHEEHTAVEKISSLVRRAALTHND 204 Score = 52.8 bits (125), Expect = 5e-07, Method: Composition-based stats. Identities = 16/72 (22%), Positives = 33/72 (45%), Gaps = 5/72 (6%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESS-KQGCYACSVVVDGEVKHCVINKTATGYGFAE 683 G +R +A+ LL G +G +++RES + GCY ++ + + + + Sbjct: 58 FHGIISREQADELLGG-VEGAYILRESQRQPGCYTLALRFGNQTLNYRLFHDGKHFV--- 113 Query: 684 PYNLYSSLKELV 695 + S+ +LV Sbjct: 114 GEKRFESIHDLV 125 >2EE4-A nrPDB Length = 209 Score = 189 bits (481), Expect = 3e-48, Method: Composition-based stats. Identities = 49/192 (25%), Positives = 87/192 (45%), Gaps = 9/192 (4%) Query: 108 VEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAELRQLLD 166 E +P L + P + K VE IE GL LYR + ++ +++ D Sbjct: 8 WESNYFGMP-LQDLVTAEKPIPLFVEKCVEFIEDTGLCTEGLYRVSGNKTDQDNIQKQFD 66 Query: 167 CDTPSVDLEMI-DVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKK 225 D + M V+ +A A K + DLP+P+IP +++ E++ A ++ E + LK+ Sbjct: 67 QDHNINLVSMEVTVNAVAGALKAFFADLPDPLIPYSLHPELLE-AAKIPDKTERLHALKE 125 Query: 226 LIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD---N 282 +++ + +Y++ H ++SQ NL+ A LS F P L R + + Sbjct: 126 IVKKFHP--VNYDVFRYVITHLNRVSQQHKINLMTADNLSICFWPTLMRPDFENREFLST 183 Query: 283 TENLIKVIEILI 294 T+ V+E I Sbjct: 184 TKIHQSVVETFI 195 >5MY3-A nrPDB Length = 226 Score = 182 bits (462), Expect = 4e-46, Method: Composition-based stats. Identities = 38/186 (20%), Positives = 91/186 (48%), Gaps = 11/186 (5%) Query: 126 DIAPPLLIKLVEAIEKKGLECSTLYRTQSSS-NLAELRQLLDCDTPSVDL-------EMI 177 D+ P ++ + + I+K GL+ +YR ++ ++++L++ +D D ++ + Sbjct: 35 DMVPAIVRQCIYVIDKFGLDQEGIYRKSANVLDVSKLKEEIDKDPANISMILPSKPHSDS 94 Query: 178 DVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYW 237 D++++ K + LP+ V+P A+ SE I + +++ + LI ++P + Sbjct: 95 DIYLVGSLLKTFFASLPDSVLPKALSSE-IKVCLQIEDPTTRKNFMHGLIY--NLPDAQY 151 Query: 238 LTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTE 297 TL+ L+ H ++ ++N +N R L I+ P + + +++ I +E+L+ Sbjct: 152 WTLRALVFHLKRVLAHEAQNRMNLRALCIIWGPTIAPANPDDANDVNFQIMAMEVLLEVS 211 Query: 298 WNERQP 303 +P Sbjct: 212 DQAFEP 217 >3BYI-A nrPDB Length = 214 Score = 179 bits (454), Expect = 4e-45, Method: Composition-based stats. Identities = 42/182 (23%), Positives = 91/182 (50%), Gaps = 9/182 (4%) Query: 126 DIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAELRQLLDCDTPSV--DLEMIDVHVL 182 P + + +EA+EK+GL+ +YR + + + +LR +++ + D + D+HV+ Sbjct: 33 STVPWFVKQCIEAVEKRGLDVDGIYRVSGNLATIQKLRFIVNQEEKLNLDDSQWEDIHVV 92 Query: 183 ADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQY 242 A K + +LP P+ P + + + + A + Q + I+ +K L++ P T++ Sbjct: 93 TGALKMFFRELPEPLFPYSFFEQFVE-AIKKQDNNTRIEAVKSLVQKLPPP--NRDTMKV 149 Query: 243 LLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLI---KVIEILISTEWN 299 L H K+ +SKNL++ + L +F P L R + + +++ ++ E+++S Sbjct: 150 LFGHLTKIVAKASKNLMSTQSLGIVFGPTLLRAENETGNMAIHMVYQNQIAELMLSEYSK 209 Query: 300 ER 301 Sbjct: 210 IF 211 >5C5S-A nrPDB Length = 232 Score = 174 bits (442), Expect = 1e-43, Method: Composition-based stats. Identities = 49/175 (28%), Positives = 82/175 (46%), Gaps = 8/175 (4%) Query: 128 APPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDCDTPSVDLEMIDVHVLADAF 186 P +L KL+E +E GL LYR ++N ELRQ L D +V LE +H + Sbjct: 28 VPIVLEKLLEHVEMHGLYTEGLYRKSGAANRTRELRQALQTDPAAVKLENFPIHAITGVL 87 Query: 187 KRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKH 246 K++L +LP P++ A Y + + + E+ + L +P +L+ L+ H Sbjct: 88 KQWLRELPEPLMTFAQYGDFLRAVELPEKQEQLAAIYAVLEH---LPEANHNSLERLIFH 144 Query: 247 FFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNER 301 K++ N ++ L+ IF+P L R DN++ L + ++L T E Sbjct: 145 LVKVALLEDVNRMSPGALAIIFAPCLLR----CPDNSDPLTSMKDVLKITTCVEM 195 >1F7C-A nrPDB Length = 231 Score = 174 bits (441), Expect = 1e-43, Method: Composition-based stats. Identities = 44/197 (22%), Positives = 79/197 (40%), Gaps = 12/197 (6%) Query: 126 DIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAE--LRQLLDCDTPSVD----LEMIDV 179 I ++ K + A+E +G+ LYR ++ + L L+D T + ++ Sbjct: 35 SIGFSIIKKCIHAVETRGINEQGLYRIVGVNSRVQKLLSILMDPKTATETETEICAEWEI 94 Query: 180 HVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLT 239 + A K YL LP P++ I A ++++ E + + L+ +P + Sbjct: 95 KTITSALKTYLRMLPGPLMMYQFQRSFIK-AAKLENQESRVSEIHSLVHR--LPEKNRQM 151 Query: 240 LQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASS---DNTENLIKVIEILIST 296 L L+ H K++ +NL+ L +F P L R + + + VIEILI Sbjct: 152 LHLLMNHLAKVADNHKQNLMTVANLGVVFGPTLLRPQEETVAAIMDIKFQNIVIEILIEN 211 Query: 297 EWNERQPAPALPPKPPK 313 P PP + Sbjct: 212 HEKIFNTVPETPPSNSQ 228 >5C2K-A nrPDB Length = 415 Score = 172 bits (435), Expect = 7e-43, Method: Composition-based stats. Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 17/198 (8%) Query: 115 LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAELR-QLLDCDTPSV 172 L D Q +P + P +++ V IE++GL + LYR + EL+ + L T + Sbjct: 220 LADFVSQTSP--MIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPL 277 Query: 173 DLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSI 232 ++ D+H + K +L +L P++ + + A E+ + I + + + + Sbjct: 278 LSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFME-AAEITDEDNSIAAMYQAVG--EL 334 Query: 233 PHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD------NTENL 286 P TL +L+ H +++Q S ++ L+++F P + + + D + + Sbjct: 335 PQANRDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQ 393 Query: 287 IKVIEILIST---EWNER 301 KV+E L+S W++ Sbjct: 394 PKVVERLLSLPLEYWSQF 411 >2FO0-A nrPDB Length = 495 Score = 171 bits (432), Expect = 1e-42, Method: Composition-based stats. Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 22/176 (12%) Query: 270 PMLFRF---SAASSDNTENLI-----KVIEILISTEWNERQPAPALPPKPPKPTTVANNG 321 P LF AS DNT ++ +V+ + EW E Q P T N Sbjct: 40 PNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN-- 97 Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 SL+ WY G +SR L +G+FLVR++ + G +++LR G Sbjct: 98 -----SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEGRVYHY 151 Query: 382 KIFH-RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV 436 +I DGK S F+++ EL++H+ + L L YP K + V Sbjct: 152 RINTASDGKLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNKPTV 202 Score = 122 bits (306), Expect = 5e-28, Method: Composition-based stats. Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 100 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 159 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 723 + + +++L ELV H+ + D L TL YP + + Sbjct: 160 KLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNK 199 >3WPS-A nrPDB Length = 208 Score = 171 bits (432), Expect = 1e-42, Method: Composition-based stats. Identities = 43/198 (21%), Positives = 90/198 (45%), Gaps = 17/198 (8%) Query: 115 LPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAELR-QLLDCDTPSV 172 L D Q +P + P +++ V IE++GL + LYR + EL+ + L T + Sbjct: 13 LADFVSQTSP--MIPSIVVHCVNEIEQRGLTETGLYRIDGCDRTVKELKEKFLRVKTVPL 70 Query: 173 DLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSI 232 ++ D+H + K +L +L P++ + + A E+ + I + + + + Sbjct: 71 LSKVDDIHAICSLLKDFLRNLKEPLLTFRLNRAFME-AAEITDEDNSIAAMYQAVG--EL 127 Query: 233 PHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSD------NTENL 286 P TL +L+ H +++Q S ++ L+++F P + + + D + + Sbjct: 128 PQANRDTLAFLMIHLQRVAQ-SPHTKMDVANLAKVFGPTIVAHAVPNPDPVTMSQDIKRQ 186 Query: 287 IKVIEILIST---EWNER 301 KV+E L+S W++ Sbjct: 187 PKVVERLLSLPLEYWSQF 204 >6AMW-A nrPDB Length = 255 Score = 168 bits (426), Expect = 6e-42, Method: Composition-based stats. Identities = 48/176 (27%), Positives = 72/176 (40%), Gaps = 22/176 (12%) Query: 270 PMLFRF---SAASSDNTENLI-----KVIEILISTEWNERQPAPALPPKPPKPTTVANNG 321 P LF AS DNT ++ +V+ + EW E Q P T N Sbjct: 82 PNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWAEAQTKNGQGWVPSNYITPVN-- 139 Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 SL+ WY G +SR L +G+FLVR++ + G +++LR G Sbjct: 140 -----SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEGRVYHY 193 Query: 382 KIFH-RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV 436 +I DGK S F+++ EL++H+ + L L YP K + V Sbjct: 194 RINTASDGKLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNKPTV 244 Score = 122 bits (305), Expect = 8e-28, Method: Composition-based stats. Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 142 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 201 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 723 + + +++L ELV H+ + D L TL YP + + Sbjct: 202 KLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNK 241 >5JD0-A nrPDB Length = 211 Score = 166 bits (419), Expect = 4e-41, Method: Composition-based stats. Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Query: 120 EQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDCDTPSVDLEMID 178 +Q + DI P ++ + + + GL +YR + + L D SV L + Sbjct: 16 QQMSRGDI-PIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGE 74 Query: 179 --VHVLADAFKRYLLDLPNPVIPAAV---YSEMISLAPEVQSSEEYIQLLKKLIRSPSIP 233 V + D KR+ +L +PV A + + E L + Q E+Y ++ L P Sbjct: 75 HFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCL------P 128 Query: 234 HQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEIL 293 TL L+ H +++ + ++ N + R L+ +F+P +F+ L ++I+ Sbjct: 129 RVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGY 188 Query: 294 IST 296 IS Sbjct: 189 ISV 191 >6GVC-R nrPDB Length = 231 Score = 166 bits (419), Expect = 4e-41, Method: Composition-based stats. Identities = 36/175 (20%), Positives = 84/175 (48%), Gaps = 10/175 (5%) Query: 126 DIAPPLLIKLVEAIEKKGLECSTLYRTQSS-SNLAELRQLLDCDTPS--VDLEMIDVHVL 182 P + +E +E+ GL+ +YR + + + +LR ++ D D + D+HV+ Sbjct: 52 GTVPKFVKLCIEHVEEHGLDVDGIYRVSGNLAVIQKLRFAVNHDEKLDLNDSKWEDIHVI 111 Query: 183 ADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQY 242 A K + +LP P+ +++ ++ Q + + +K LIR P+Q T+Q Sbjct: 112 TGALKMFFRELPEPLFTFNHFNDFVNAIK--QEPRQRVTAVKDLIRQLPKPNQD--TMQI 167 Query: 243 LLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLI---KVIEILI 294 L +H ++ + KN + + ++ +F P L + + + + + +++E+++ Sbjct: 168 LFRHLKRVIENGEKNRMTYQSIAIVFGPTLLKPERETGNIAVHTVYQNQIVELIL 222 >5JCP-B nrPDB Length = 419 Score = 166 bits (419), Expect = 5e-41, Method: Composition-based stats. Identities = 42/183 (22%), Positives = 79/183 (43%), Gaps = 13/183 (7%) Query: 120 EQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDCDTPSVDLEMID 178 +Q + DI P ++ + + + GL +YR + + L D SV L + Sbjct: 16 QQMSRGDI-PIIVDACISFVTQHGLRLEGVYRKGGARARSLRLLAEFRRDARSVKLRPGE 74 Query: 179 --VHVLADAFKRYLLDLPNPVIPAAV---YSEMISLAPEVQSSEEYIQLLKKLIRSPSIP 233 V + D KR+ +L +PV A + + E L + Q E+Y ++ L P Sbjct: 75 HFVEDVTDTLKRFFRELDDPVTSARLLPRWREAAELPQKNQRLEKYKDVIGCL------P 128 Query: 234 HQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEIL 293 TL L+ H +++ + ++ N + R L+ +F+P +F+ L ++I+ Sbjct: 129 RVNRRTLATLIGHLYRVQKCAALNQMCTRNLALLFAPSVFQTDGRGEHEVRVLQELIDGY 188 Query: 294 IST 296 IS Sbjct: 189 ISV 191 >2MBG-A nrPDB Length = 265 Score = 162 bits (410), Expect = 5e-40, Method: Composition-based stats. Identities = 47/210 (22%), Positives = 93/210 (44%), Gaps = 21/210 (10%) Query: 112 ALTLPDLAEQFAPPDIA--PPLLIKLVEAIEKKGLECSTLYRTQS-SSNLAELRQLLDCD 168 + L D E+ D P + + ++ +EK G++C +YR S + EL+ D + Sbjct: 10 GIPLADAVERTMMYDGIRLPAVFRECIDYVEKYGMKCEGIYRVSGIKSKVDELKAAYDRE 69 Query: 169 TPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAV---YSEMISLAPEVQSSEEYIQLLKK 225 S +LE + + +A K+YL DLP ++ + + E E + +E+ +LLK+ Sbjct: 70 -ESTNLEDYEPNTVASLLKQYLRDLPENLLTKELMPRFEEACGRTTETEKVQEFQRLLKE 128 Query: 226 LIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPM-------LFRFSAA 278 L P +L + +L+ H + + +N + +S + SP L+ F Sbjct: 129 L------PECNYLLISWLIVHMDHVIAKELETKMNIQNISIVLSPTVQISNRVLYVFFTH 182 Query: 279 SSDNTENLIKVIEILISTEWNERQPAPALP 308 + N++ + +++ W+ P LP Sbjct: 183 VQELFGNVV-LKQVMKPLRWSNMATMPTLP 211 >2ABL-A nrPDB Length = 163 Score = 161 bits (408), Expect = 8e-40, Method: Composition-based stats. Identities = 46/169 (27%), Positives = 69/169 (40%), Gaps = 22/169 (13%) Query: 270 PMLFRF---SAASSDNTENLI-----KVIEILISTEWNERQPAPALPPKPPKPTTVANNG 321 P LF AS DNT ++ +V+ + EW E Q P T N Sbjct: 8 PNLFVALYDFVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN-- 65 Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 SL+ WY G +SR L +G+FLVR++ + G +++LR G Sbjct: 66 -----SLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEGRVYHY 119 Query: 382 KIFH-RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVS 429 +I DGK S F+++ EL++H+ + L L YP Sbjct: 120 RINTASDGKLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAP 163 Score = 120 bits (301), Expect = 2e-27, Method: Composition-based stats. Identities = 35/100 (35%), Positives = 52/100 (52%), Gaps = 6/100 (6%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 68 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 127 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + +++L ELV H+ + D L TL YP Sbjct: 128 KLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPA 162 >3IUG-A nrPDB Length = 229 Score = 159 bits (401), Expect = 5e-39, Method: Composition-based stats. Identities = 45/190 (23%), Positives = 84/190 (44%), Gaps = 9/190 (4%) Query: 117 DLAEQFAPPDIAPPLLIK-LVEAIEKKGLECSTLYRTQS-SSNLAELRQLLDCDTPSVDL 174 DL E P +++ IE+ G+ +YR +SN+ LR D + Sbjct: 25 DLGEHLLNSGFEVPQVLQSCTAFIERYGI-VDGIYRLSGVASNIQRLRHEFDSEHVPDLT 83 Query: 175 E---MIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPS 231 + + D+H + K Y +LPNP++ +Y + S A + EE + + +I+ Sbjct: 84 KEPYVQDIHSVGSLCKLYFRELPNPLLTYQLYEKF-SDAVSAATDEERLIKIHDVIQQLP 142 Query: 232 IPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIKVIE 291 PH + TL++L++H L+ S ++A+ L+ +++P L R S +E Sbjct: 143 PPH--YRTLEFLMRHLSLLADYCSITNMHAKNLAIVWAPNLLRSKQIESACFSGTAAFME 200 Query: 292 ILISTEWNER 301 + I + E Sbjct: 201 VRIQSVVVEF 210 >2XS6-A nrPDB Length = 214 Score = 156 bits (393), Expect = 5e-38, Method: Composition-based stats. Identities = 53/162 (32%), Positives = 82/162 (50%), Gaps = 14/162 (8%) Query: 108 VEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDC 167 + LTLPDL EQF+PPD+APPLL+KLVEAIE+ GL+ + YR + + Sbjct: 20 FQSMGLTLPDLPEQFSPPDVAPPLLVKLVEAIERTGLDSESHYRPELPAPRT-------- 71 Query: 168 DTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLI 227 D D++ D LAD K +LL LP P++ +E ++ E + + Sbjct: 72 DWSLSDVDQWDTAALADGIKSFLLALPAPLVTPEASAEA------RRALREAAGPVGPAL 125 Query: 228 RSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFS 269 P++P LTL++LL+H ++++ + R L F Sbjct: 126 EPPTLPLHRALTLRFLLQHLGRVARRAPALGPAVRALGATFG 167 >3T04-A nrPDB Length = 123 Score = 138 bits (347), Expect = 1e-32, Method: Composition-based stats. Identities = 33/120 (27%), Positives = 54/120 (45%), Gaps = 7/120 (5%) Query: 318 ANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGN 377 +N + SL+ WY G +SR L +G+FLVR++ + G +++LR G Sbjct: 3 PSNYITPVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEGR 61 Query: 378 NKLIKIFH-RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV 436 +I DGK S F+++ EL++H+ + L L YP K + V Sbjct: 62 VYHYRINTASDGKLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNKPTV 116 Score = 120 bits (300), Expect = 2e-27, Method: Composition-based stats. Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 14 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 73 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 723 + + +++L ELV H+ + D L TL YP + + Sbjct: 74 KLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNK 113 >4XEY-B nrPDB Length = 408 Score = 135 bits (340), Expect = 7e-32, Method: Composition-based stats. Identities = 33/116 (28%), Positives = 53/116 (45%), Gaps = 7/116 (6%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 M + SL+ WY G +SR L +G+FLVR++ + G +++LR G Sbjct: 1 MASVNSLEKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESS-PGQRSISLRYEGRVYHY 59 Query: 382 KIFH-RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV 436 +I DGK S F+++ EL++H+ + L L YP K + V Sbjct: 60 RINTASDGKLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNKPTV 110 Score = 122 bits (306), Expect = 5e-28, Method: Composition-based stats. Identities = 35/105 (33%), Positives = 54/105 (51%), Gaps = 6/105 (5%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATG 678 ++ +W G +RN AE LL +G+FLVRES S G + S+ +G V H IN + G Sbjct: 8 EKHSWYHGPVSRNAAEYLLSSGINGSFLVRESESSPGQRSISLRYEGRVYHYRINTASDG 67 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 723 + + +++L ELV H+ + D L TL YP + + Sbjct: 68 KLYVSSESRFNTLAELVHHHSTVA-----DGLITTLHYPAPKRNK 107 >2CRH-A nrPDB Length = 138 Score = 132 bits (332), Expect = 6e-31, Method: Composition-based stats. Identities = 41/112 (36%), Positives = 54/112 (48%), Gaps = 5/112 (4%) Query: 614 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQG-CYACSVVVDGEVKHCVI 672 +DL H W G R AE++L + DGTFLVR+ K +A S+ + EVKH I Sbjct: 21 QDLSVH---LWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI 77 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 724 TA G + L ELV YQ SL SL+ TL +P ++R Sbjct: 78 -MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKR 128 Score = 116 bits (291), Expect = 3e-26, Method: Composition-based stats. Identities = 31/120 (25%), Positives = 52/120 (43%), Gaps = 1/120 (0%) Query: 319 NNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNN 378 N L WY G + R L + +DGTFLVR K ++ ++++ Sbjct: 14 NWWEGPPQDLSVHLWYAGPMERAGAESILANRSDGTFLVRQ-RVKDAAEFAISIKYNVEV 72 Query: 379 KLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVK 438 K IKI +G Y ++ F + EL+ Y+ SL LD L +P + ++ + + Sbjct: 73 KHIKIMTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKEPEKRTISR 132 >2LCT-A nrPDB Length = 107 Score = 127 bits (320), Expect = 1e-29, Method: Composition-based stats. Identities = 40/108 (37%), Positives = 51/108 (47%), Gaps = 5/108 (4%) Query: 614 EDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQG-CYACSVVVDGEVKHCVI 672 +DL H W G R AE++L + DGTFLVR+ K +A S+ + EVKH I Sbjct: 4 QDLSVH---LWYAGPMERAGAESILANRSDGTFLVRQRVKDAAEFAISIKYNVEVKHIKI 60 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 TA G + L ELV YQ SL SL+ TL +P Sbjct: 61 -MTAEGLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFPFKE 107 Score = 116 bits (290), Expect = 4e-26, Method: Composition-based stats. Identities = 30/100 (30%), Positives = 46/100 (46%), Gaps = 1/100 (1%) Query: 328 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 L WY G + R L + +DGTFLVR K ++ ++++ K IKI + Sbjct: 6 LSVHLWYAGPMERAGAESILANRSDGTFLVRQ-RVKDAAEFAISIKYNVEVKHIKIMTAE 64 Query: 388 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 427 G Y ++ F + EL+ Y+ SL LD L +P Sbjct: 65 GLYRITEKKAFRGLTELVEFYQQNSLKDCFKSLDTTLQFP 104 >1A81-A nrPDB Length = 254 Score = 127 bits (319), Expect = 2e-29, Method: Composition-based stats. Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Query: 619 HDEKTWNVGSSNRNKAEN--LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H++ W G +R ++E L+ K +G FL+R G YA ++ +G+V H I+K Sbjct: 155 HEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDK 214 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 TG + +L +LV HY + + D L L P Sbjct: 215 TGKLSIPEGKKFDTLWQLVEHYSYKA-----DGLLRVLTVPCQK 253 Score = 76.7 bits (187), Expect = 4e-14, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 54/145 (37%), Gaps = 13/145 (8%) Query: 289 VIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNE--K 346 +I + WN + A KP + + + W+ G ISREE + Sbjct: 119 LIREYVKQTWNLQGQALEQAIISQKPQL---EKLIATTAHEKMPWFHGKISREESEQIVL 175 Query: 347 LRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH-RDGKYGFSDPLTFSSVVELI 405 + +G FL+R + +G Y L L G +I + GK + F ++ +L+ Sbjct: 176 IGSKTNGKFLIR--ARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV 233 Query: 406 NHYRNESLAQYNPKLDVKLLYPVSK 430 HY + L L P K Sbjct: 234 EHY-----SYKADGLLRVLTVPCQK 253 Score = 63.6 bits (153), Expect = 3e-10, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 8/103 (7%) Query: 623 TWNVGSSNRNKAENLL--RGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATGY 679 + G+ R +AE+ L G DG +L+R+S G +A SV + H I + G Sbjct: 6 PFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGT 65 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 ++S +L ++ S D L L P Q Sbjct: 66 YAIAGGRTHASPADLCHYHSQES-----DGLVCLLKKPFNRPQ 103 Score = 59.3 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 26/110 (23%), Positives = 48/110 (43%), Gaps = 12/110 (10%) Query: 332 EWYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR-DG 388 +++G+I+REE + L DG +L+R + G + L++ G I +G Sbjct: 6 PFFFGNITREEAEDYLVQGGMSDGLYLLRQSR-NYLGGFALSVAHGRKAHHYTIERELNG 64 Query: 389 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVK 438 Y + T +S +L +++ ES L L P + + Q V+ Sbjct: 65 TYAIAGGRTHASPADLCHYHSQES-----DGLVCLLKKP---FNRPQGVQ 106 >4FL3-A nrPDB Length = 635 Score = 127 bits (318), Expect = 2e-29, Method: Composition-based stats. Identities = 30/104 (28%), Positives = 48/104 (46%), Gaps = 7/104 (6%) Query: 619 HDEKTWNVGSSNRNKAEN--LLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H++ W G +R ++E L+ K +G FL+R G YA ++ +G+V H I+K Sbjct: 163 HEKMPWFHGKISREESEQIVLIGSKTNGKFLIRARDNNGSYALCLLHEGKVLHYRIDKDK 222 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 TG + +L +LV HY + + D L L P Sbjct: 223 TGKLSIPEGKKFDTLWQLVEHYSYKA-----DGLLRVLTVPCQK 261 Score = 76.3 bits (186), Expect = 4e-14, Method: Composition-based stats. Identities = 33/145 (22%), Positives = 54/145 (37%), Gaps = 13/145 (8%) Query: 289 VIEILISTEWNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNE--K 346 +I + WN + A KP + + + W+ G ISREE + Sbjct: 127 LIREYVKQTWNLQGQALEQAIISQKPQL---EKLIATTAHEKMPWFHGKISREESEQIVL 183 Query: 347 LRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFH-RDGKYGFSDPLTFSSVVELI 405 + +G FL+R + +G Y L L G +I + GK + F ++ +L+ Sbjct: 184 IGSKTNGKFLIR--ARDNNGSYALCLLHEGKVLHYRIDKDKTGKLSIPEGKKFDTLWQLV 241 Query: 406 NHYRNESLAQYNPKLDVKLLYPVSK 430 HY + L L P K Sbjct: 242 EHY-----SYKADGLLRVLTVPCQK 261 Score = 63.2 bits (152), Expect = 3e-10, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 41/103 (39%), Gaps = 8/103 (7%) Query: 623 TWNVGSSNRNKAENLL--RGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATGY 679 + G+ R +AE+ L G DG +L+R+S G +A SV + H I + G Sbjct: 14 PFFFGNITREEAEDYLVQGGMSDGLYLLRQSRNYLGGFALSVAHGRKAHHYTIERELNGT 73 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 ++S +L ++ S D L L P Q Sbjct: 74 YAIAGGRTHASPADLCHYHSQES-----DGLVCLLKKPFNRPQ 111 Score = 60.1 bits (144), Expect = 4e-09, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 55/125 (44%), Gaps = 14/125 (11%) Query: 317 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRK 374 +A++GM S +++G+I+REE + L DG +L+R + G + L++ Sbjct: 1 MASSGMA--DSANHLPFFFGNITREEAEDYLVQGGMSDGLYLLRQSR-NYLGGFALSVAH 57 Query: 375 GGNNKLIKIFHR-DGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQ 433 G I +G Y + T +S +L +++ ES L L P + + Sbjct: 58 GRKAHHYTIERELNGTYAIAGGRTHASPADLCHYHSQES-----DGLVCLLKKP---FNR 109 Query: 434 DQVVK 438 Q V+ Sbjct: 110 PQGVQ 114 >1K9A-A nrPDB Length = 450 Score = 124 bits (312), Expect = 1e-28, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 66/166 (39%), Gaps = 10/166 (6%) Query: 286 LIKVIEILISTEW-NERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVN 344 ++ ++ + W + P G+ L W+ G I+RE+ Sbjct: 35 VLTIVAVTKDPNWYKAKNKVGREGIIPANYVQ-KREGVKAGTKLSLMPWFHGKITREQAE 93 Query: 345 EKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVEL 404 L G FLVR++ T GDYTL + G + +I + K + + F ++++L Sbjct: 94 RLLYPPETGLFLVRES-TNYPGDYTLCVSCEGKVEHYRIMYHASKLSIDEEVYFENLMQL 152 Query: 405 INHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLH 450 + HY ++ L +L+ P K + V +D G L+ Sbjct: 153 VEHYTTDA-----DGLCTRLIKP--KVMEGTVAAQDEFYRSGWALN 191 Score = 93.2 bits (230), Expect = 3e-19, Method: Composition-based stats. Identities = 31/97 (31%), Positives = 41/97 (42%), Gaps = 7/97 (7%) Query: 622 KTWNVGSSNRNKAENLLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATGYG 680 W G R +AE LL G FLVRES+ G Y V +G+V+H I A Sbjct: 80 MPWFHGKITREQAERLLYPPETGLFLVRESTNYPGDYTLCVSCEGKVEHYRIMYHA-SKL 138 Query: 681 FAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYP 717 + + +L +LV HY + D L L P Sbjct: 139 SIDEEVYFENLMQLVEHYTTDA-----DGLCTRLIKP 170 >4XI2-A nrPDB Length = 446 Score = 120 bits (300), Expect = 3e-27, Method: Composition-based stats. Identities = 50/187 (26%), Positives = 86/187 (45%), Gaps = 30/187 (16%) Query: 548 DLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLG-NENTEDQ 606 +LKK A Y + N + QLRK + +++ + L W ++N ++ Sbjct: 2 ELKKVVALYDYMPMNANDL-----QLRKGEEYFIL-------EESNLPWWRARDKNGQEG 49 Query: 607 Y---SLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCYACSVV 662 Y + + + ED + W R++AE LL+ + ++G F+VR+SSK G Y SV Sbjct: 50 YIPSNYITEAED--SIEMYEWYSKHMTRSQAEQLLKQEGKEGGFIVRDSSKAGKYTVSVF 107 Query: 663 V------DGEVKHCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAY 716 G ++H V+ T + +L+S++ EL+ ++QH S L L Y Sbjct: 108 AKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQHNS-----AGLISRLKY 162 Query: 717 PVYAQQR 723 PV Q + Sbjct: 163 PVSKQNK 169 Score = 90.9 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 36/145 (24%), Positives = 65/145 (44%), Gaps = 21/145 (14%) Query: 298 WNERQPAPALPPKPPKPTTVANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTA-DGTFL 356 W R P T S++ EWY ++R + + L+ +G F+ Sbjct: 39 WRARDKNGQEGYIPSNYIT------EAEDSIEMYEWYSKHMTRSQAEQLLKQEGKEGGFI 92 Query: 357 VRDASTKMHGDYTLTL--RKGGNNKL-IKIF----HRDGKYGFSDPLTFSSVVELINHYR 409 VRD+S G YT+++ + G + I+ + +Y ++ FS++ ELIN+++ Sbjct: 93 VRDSS--KAGKYTVSVFAKSTGEPQGVIRHYVVCSTPQSQYYLAEKHLFSTIPELINYHQ 150 Query: 410 NESLAQYNPKLDVKLLYPVSKYQQD 434 + S L +L YPVSK ++ Sbjct: 151 HNSA-----GLISRLKYPVSKQNKN 170 >2VIF-A nrPDB Length = 141 Score = 117 bits (292), Expect = 2e-26, Method: Composition-based stats. Identities = 39/120 (32%), Positives = 58/120 (48%), Gaps = 14/120 (11%) Query: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR 386 L WYWG I+R E KL + DG+FLVRD+S + +L+ R G +I H Sbjct: 20 KLAKQGWYWGPITRWEAEGKLANVPDGSFLVRDSSDDRY-LLSLSFRSHGKTLHTRIEHS 78 Query: 387 DGKYGF---SDPLTFSSVVELINH----YRNESLAQYNPKL------DVKLLYPVSKYQQ 433 +G++ F D +S+V+LI H N + +L V+L PVS++ Q Sbjct: 79 NGRFSFYEQPDVEGHTSIVDLIEHSIGDSENGAFCYSRSRLPGSATYPVRLTNPVSRFMQ 138 Score = 63.2 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 32/130 (24%), Positives = 51/130 (39%), Gaps = 18/130 (13%) Query: 605 DQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCY--ACSVV 662 D SL E+ + L ++ W G R +AE L DG+FLVR+SS Y + S Sbjct: 10 DVTSLTEELKKLA---KQGWYWGPITRWEAEGKLANVPDGSFLVRDSS-DDRYLLSLSFR 65 Query: 663 VDGEVKHCVI-NKTAT-GYGFAEPYNLYSSLKELVLHY----------QHTSLVQHNDSL 710 G+ H I + + ++S+ +L+ H S + + + Sbjct: 66 SHGKTLHTRIEHSNGRFSFYEQPDVEGHTSIVDLIEHSIGDSENGAFCYSRSRLPGSATY 125 Query: 711 NVTLAYPVYA 720 V L PV Sbjct: 126 PVRLTNPVSR 135 >2EKX-A nrPDB Length = 110 Score = 117 bits (292), Expect = 3e-26, Method: Composition-based stats. Identities = 31/107 (28%), Positives = 53/107 (49%), Gaps = 12/107 (11%) Query: 620 DEKTWNVGSSNRNKAENLLRGK-RDGTFLVRESSKQGCYACSVVVD------GEVKHCVI 672 D+ W G+ +R+++E LLR K ++G F+VR SS+ G Y S+ G VKH + Sbjct: 9 DDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQVGMYTVSLFSKAVNDKKGTVKHYHV 68 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVY 719 + A + + S+ +L+ ++QH S + L +PV Sbjct: 69 HTNAENKLYLAENYCFDSIPKLIHYHQHNS-----AGMITRLRHPVS 110 Score = 102 bits (253), Expect = 7e-22, Method: Composition-based stats. Identities = 32/117 (27%), Positives = 59/117 (50%), Gaps = 15/117 (12%) Query: 321 GMNNNMSLQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTL------R 373 G + + L D +W+ G+ISR + + LR +G F+VR++S G YT++L Sbjct: 1 GSSGSSGLDDYDWFAGNISRSQSEQLLRQKGKEGAFMVRNSSQV--GMYTVSLFSKAVND 58 Query: 374 KGGNNKLIKIFH-RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVS 429 K G K + + K ++ F S+ +LI+++++ S + +L +PVS Sbjct: 59 KKGTVKHYHVHTNAENKLYLAENYCFDSIPKLIHYHQHNSA-----GMITRLRHPVS 110 >2EOB-A nrPDB Length = 124 Score = 113 bits (283), Expect = 3e-25, Method: Composition-based stats. Identities = 34/101 (33%), Positives = 51/101 (50%), Gaps = 7/101 (6%) Query: 619 HDEKTWNVGSSNRNKAENLL-RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTAT 677 H+ K W +R +AE++L R RDG FL+R+ YA + G+VKHC IN+ Sbjct: 16 HESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTDSYAITFRARGKVKHCRINRDGR 75 Query: 678 GYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 + + SL ELV +Y+ +L + + L YPV Sbjct: 76 HFVLGTS-AYFESLVELVSYYEKHALYR-----KMRLRYPV 110 Score = 68.6 bits (166), Expect = 8e-12, Method: Composition-based stats. Identities = 29/102 (28%), Positives = 46/102 (45%), Gaps = 8/102 (7%) Query: 329 QDAEWYWGDISREEVNEKL-RDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 + WY+ +SR E + L R DG FL+R Y +T R G K +I Sbjct: 17 ESKPWYYDRLSRGEAEDMLMRIPRDGAFLIRKREGTD--SYAITFRARGKVKHCRINRDG 74 Query: 388 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVS 429 + F S+VEL+++Y +L + ++L YPV+ Sbjct: 75 RHFVLGTSAYFESLVELVSYYEKHALYRK-----MRLRYPVT 111 >2PLE-A nrPDB Length = 105 Score = 112 bits (281), Expect = 4e-25, Method: Composition-based stats. Identities = 31/106 (29%), Positives = 52/106 (49%), Gaps = 8/106 (7%) Query: 618 HHDEKTWNVGSSNRNKAENLL-RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H+ K W S R +AE++L R RDG FLVR+ ++ YA S +G++KHC + + Sbjct: 5 IHESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKRNEPNSYAISFRAEGKIKHCRVQQEG 64 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 + SL +L+ +Y+ L + + L YP+ + Sbjct: 65 QTVMLGNSE--FDSLVDLISYYEKHPLYR-----KMKLRYPINEEN 103 Score = 67.0 bits (162), Expect = 2e-11, Method: Composition-based stats. Identities = 28/105 (26%), Positives = 48/105 (45%), Gaps = 9/105 (8%) Query: 329 QDAEWYWGDISREEVNEKL-RDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 + EWY ++R + L R DG FLVR Y ++ R G K ++ ++ Sbjct: 7 ESKEWYHASLTRAQAEHMLMRVPRDGAFLVRKR--NEPNSYAISFRAEGKIKHCRVQ-QE 63 Query: 388 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQ 432 G+ F S+V+LI++Y L + +KL YP+++ Sbjct: 64 GQTVMLGNSEFDSLVDLISYYEKHPLYRK-----MKLRYPINEEN 103 >2KK6-A nrPDB Length = 116 Score = 109 bits (272), Expect = 5e-24, Method: Composition-based stats. Identities = 34/106 (32%), Positives = 53/106 (50%), Gaps = 5/106 (4%) Query: 328 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 L + +WY G I R E E L+ D FLVR++ K G+Y L++ G + I + D Sbjct: 14 LAEQDWYHGAIPRIEAQELLKKQGD--FLVRESHGK-PGEYVLSVYSDGQRRHFIIQYVD 70 Query: 388 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQ 433 Y F + FS++ +LI+H+ K V LL P+ K ++ Sbjct: 71 NMYRF-EGTGFSNIPQLIDHHYTTKQV-ITKKSGVVLLNPIPKDKK 114 Score = 103 bits (257), Expect = 3e-22, Method: Composition-based stats. Identities = 35/104 (33%), Positives = 52/104 (50%), Gaps = 6/104 (5%) Query: 621 EKTWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATGY 679 E+ W G+ R +A+ LL K+ G FLVRES K G Y SV DG+ +H +I Y Sbjct: 16 EQDWYHGAIPRIEAQELL--KKQGDFLVRESHGKPGEYVLSVYSDGQRRHFIIQYVDNMY 73 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQR 723 F +S++ +L+ H+ T V S V L P+ ++ Sbjct: 74 RF--EGTGFSNIPQLIDHHYTTKQVITKKS-GVVLLNPIPKDKK 114 >6F3F-A nrPDB Length = 455 Score = 108 bits (270), Expect = 8e-24, Method: Composition-based stats. Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 12/131 (9%) Query: 317 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRD--TADGTFLVRDASTKMHGDYTLTLR- 373 + +N + + S+Q EWY+G I+R E L + GTFLVR++ T G Y L++ Sbjct: 54 IPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETT-KGAYCLSVSD 112 Query: 374 ----KGGNNKLIKIFHRD-GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPV 428 KG N K KI D G + + F+S+ +L+ +Y + + + + P Sbjct: 113 FDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHR---LTTVCPT 169 Query: 429 SKYQQDQVVKE 439 SK Q + K+ Sbjct: 170 SKPQTQGLAKD 180 Score = 79.0 bits (193), Expect = 6e-15, Method: Composition-based stats. Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 22/156 (14%) Query: 586 QKGVRQKKLNE-----WLGNENTEDQYSLVEDDEDLPHH--DEKTWNVGSSNRNKAENLL 638 +KG R + +N WL + + Q + + P + W G R ++E LL Sbjct: 25 KKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLL 84 Query: 639 RGKRD--GTFLVRESSKQ-GCYACSVV----VDG-EVKHCVINKTATGYGFAEPYNLYSS 690 + GTFLVRES G Y SV G VKH I K +G + ++S Sbjct: 85 LNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNS 144 Query: 691 LKELVLHYQHTSLVQHNDSLNVTLAY--PVYAQQRR 724 L++LV +Y + D L L P Q + Sbjct: 145 LQQLVAYYSKHA-----DGLCHRLTTVCPTSKPQTQ 175 >2H8H-A nrPDB Length = 535 Score = 108 bits (270), Expect = 9e-24, Method: Composition-based stats. Identities = 38/131 (29%), Positives = 63/131 (48%), Gaps = 12/131 (9%) Query: 317 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRD--TADGTFLVRDASTKMHGDYTLTLR- 373 + +N + + S+Q EWY+G I+R E L + GTFLVR++ T G Y L++ Sbjct: 134 IPSNYVAPSDSIQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETT-KGAYCLSVSD 192 Query: 374 ----KGGNNKLIKIFHRD-GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPV 428 KG N K KI D G + + F+S+ +L+ +Y + + + + P Sbjct: 193 FDNAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHR---LTTVCPT 249 Query: 429 SKYQQDQVVKE 439 SK Q + K+ Sbjct: 250 SKPQTQGLAKD 260 Score = 79.0 bits (193), Expect = 7e-15, Method: Composition-based stats. Identities = 43/156 (27%), Positives = 63/156 (40%), Gaps = 22/156 (14%) Query: 586 QKGVRQKKLNE-----WLGNENTEDQYSLVEDDEDLPHH--DEKTWNVGSSNRNKAENLL 638 +KG R + +N WL + + Q + + P + W G R ++E LL Sbjct: 105 KKGERLQIVNNTEGDWWLAHSLSTGQTGYIPSNYVAPSDSIQAEEWYFGKITRRESERLL 164 Query: 639 RGKRD--GTFLVRESSKQ-GCYACSVV----VDG-EVKHCVINKTATGYGFAEPYNLYSS 690 + GTFLVRES G Y SV G VKH I K +G + ++S Sbjct: 165 LNAENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFNS 224 Query: 691 LKELVLHYQHTSLVQHNDSLNVTLAY--PVYAQQRR 724 L++LV +Y + D L L P Q + Sbjct: 225 LQQLVAYYSKHA-----DGLCHRLTTVCPTSKPQTQ 255 >1GRN-B nrPDB Length = 203 Score = 105 bits (261), Expect = 8e-23, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 87/199 (43%), Gaps = 6/199 (3%) Query: 109 EQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDC 167 +Q ++L L E+ + P +L + V ++ L ++R +++ + E++Q + Sbjct: 4 QQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNM 63 Query: 168 DTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLI 227 P + ++H+ A K +L +LP P++ +Y ++ + +E ++ L Sbjct: 64 GLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFL----NIDESQRVPATLQ 119 Query: 228 RSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLF-RFSAASSDNTENL 286 ++P + + L++L ++S S +N + L+ +F P L AA + N Sbjct: 120 VLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINP 179 Query: 287 IKVIEILISTEWNERQPAP 305 I + E P+P Sbjct: 180 INTFTKFLLDHQGELFPSP 198 >1OW3-A nrPDB Length = 242 Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 87/199 (43%), Gaps = 6/199 (3%) Query: 109 EQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDC 167 +Q ++L L E+ + P +L + V ++ L ++R +++ + E++Q + Sbjct: 43 QQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNM 102 Query: 168 DTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLI 227 P + ++H+ A K +L +LP P++ +Y ++ + +E ++ L Sbjct: 103 GLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFL----NIDESQRVPATLQ 158 Query: 228 RSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLF-RFSAASSDNTENL 286 ++P + + L++L ++S S +N + L+ +F P L AA + N Sbjct: 159 VLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINP 218 Query: 287 IKVIEILISTEWNERQPAP 305 I + E P+P Sbjct: 219 INTFTKFLLDHQGELFPSP 237 >1AD5-A nrPDB Length = 438 Score = 104 bits (260), Expect = 1e-22, Method: Composition-based stats. Identities = 35/109 (32%), Positives = 60/109 (55%), Gaps = 11/109 (10%) Query: 317 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTAD--GTFLVRDASTKMHGDYTLTL-- 372 + +N + SL+ EW++ ISR++ +L + G+F++RD+ T G Y+L++ Sbjct: 50 IPSNYVARVDSLETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETT-KGSYSLSVRD 108 Query: 373 ---RKGGNNKLIKIFHRD-GKYGFSDPLTFSSVVELINHYR--NESLAQ 415 R+G K KI D G + S TFS++ EL++HY+ N+ L Q Sbjct: 109 YDPRQGDTVKHYKIRTLDNGGFYISPRSTFSTLQELVDHYKKGNDGLCQ 157 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 32/114 (28%), Positives = 49/114 (42%), Gaps = 15/114 (13%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRD--GTFLVRESSKQ-GCYACSVV-----VDGEVKHCV 671 + + W +R AE L + G+F++R+S G Y+ SV VKH Sbjct: 62 ETEEWFFKGISRKDAERQLLAPGNMLGSFMIRDSETTKGSYSLSVRDYDPRQGDTVKHYK 121 Query: 672 INKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV--YAQQR 723 I G + P + +S+L+ELV HY+ ND L L+ P Q+ Sbjct: 122 IRTLDNGGFYISPRSTFSTLQELVDHYKK-----GNDGLCQKLSVPCMSSKPQK 170 >6R3V-A nrPDB Length = 439 Score = 104 bits (259), Expect = 2e-22, Method: Composition-based stats. Identities = 39/199 (19%), Positives = 87/199 (43%), Gaps = 6/199 (3%) Query: 109 EQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLA-ELRQLLDC 167 +Q ++L L E+ + P +L + V ++ L ++R +++ + E++Q + Sbjct: 240 QQFGVSLQHLQEKNPEQEPIPIVLRETVAYLQAHALTTEGIFRRSANTQVVREVQQKYNM 299 Query: 168 DTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLI 227 P + ++H+ A K +L +LP P++ +Y ++ + +E ++ L Sbjct: 300 GLPVDFDQYNELHLPAVILKTFLRELPEPLLTFDLYPHVVGFL----NIDESQRVPATLQ 355 Query: 228 RSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLF-RFSAASSDNTENL 286 ++P + + L++L ++S S +N + L+ +F P L AA + N Sbjct: 356 VLQTLPEENYQVLRFLTAFLVQISAHSDQNKMTNTNLAVVFGPNLLWAKDAAITLKAINP 415 Query: 287 IKVIEILISTEWNERQPAP 305 I + E P+P Sbjct: 416 INTFTKFLLDHQGELFPSP 434 >1GRI-A nrPDB Length = 217 Score = 103 bits (256), Expect = 4e-22, Method: Composition-based stats. Identities = 29/117 (24%), Positives = 64/117 (54%), Gaps = 5/117 (4%) Query: 323 NNNMSLQDAEWYWGDISREEVNEKL-RDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 N + ++ W++G I R + E L + DG FL+R++ GD++L+++ G + + Sbjct: 50 KNYIEMKPHPWFFGKIPRAKAEEMLSKQRHDGAFLIRESE-SAPGDFSLSVKFGNDVQHF 108 Query: 382 KIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVK 438 K+ F + F+S+ EL++++R+ S+++ N ++ ++ + V QQ V+ Sbjct: 109 KVLRDGAGKYFLWVVKFNSLNELVDYHRSTSVSR-NQQIFLRDIEQVP--QQPTYVQ 162 Score = 101 bits (251), Expect = 1e-21, Method: Composition-based stats. Identities = 30/86 (34%), Positives = 46/86 (53%), Gaps = 3/86 (3%) Query: 622 KTWNVGSSNRNKAENLLRGKR-DGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATGY 679 W G R KAE +L +R DG FL+RES S G ++ SV +V+H + + G Sbjct: 58 HPWFFGKIPRAKAEEMLSKQRHDGAFLIRESESAPGDFSLSVKFGNDVQHFKVLRDGAGK 117 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQ 705 F ++SL ELV +++ TS+ + Sbjct: 118 YFLWVVK-FNSLNELVDYHRSTSVSR 142 >3KUQ-A nrPDB Length = 228 Score = 100 bits (250), Expect = 2e-21, Method: Composition-based stats. Identities = 34/182 (18%), Positives = 70/182 (38%), Gaps = 4/182 (2%) Query: 108 VEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQS-SSNLAELRQLLD 166 + +P P + + + + L+ L+R S + LRQ+ + Sbjct: 16 FQGSVFGVPLTVNVQRTGQPLPQSIQQAMRYLRNHCLDQVGLFRKSGVKSRIQALRQMNE 75 Query: 167 CDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKL 226 V+ E + +AD K+Y DLP P++ + + + V ++ +Q +K Sbjct: 76 GAIDCVNYEGQSAYDVADMLKQYFRDLPEPLMTNKLSETFLQIYQYVPK-DQRLQAIKAA 134 Query: 227 IRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENL 286 I +P + LQ LL ++ +N + L+ +P LF + +N+ Sbjct: 135 IML--LPDENREVLQTLLYFLSDVTAAVKENQMTPTNLAVCLAPSLFHLNTLKRENSSPR 192 Query: 287 IK 288 + Sbjct: 193 VM 194 >6C7Y-B nrPDB Length = 117 Score = 98.6 bits (244), Expect = 9e-21, Method: Composition-based stats. Identities = 25/108 (23%), Positives = 51/108 (47%), Gaps = 6/108 (5%) Query: 319 NNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNN 378 ++ + L +YWG ++ +EKL+ +GTFL+RD+ T+ + + ++++ Sbjct: 14 SSITRASSLLDACGFYWGPLTVSAAHEKLKSEPEGTFLIRDS-TQKNCFFAISVKTATGP 72 Query: 379 KLIKIFHRDGKYGFS-DPLTFSSVVELINHYRNESLAQYNPKLDVKLL 425 I+I + G++ TF + +L+ HY L+ L L Sbjct: 73 TSIRINFQTGRFSLDGSKETFDCLFKLLEHY----LSSPRKVLVTPLR 116 Score = 53.9 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 19/79 (24%), Positives = 34/79 (43%), Gaps = 1/79 (1%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVINKTATGYGFAE 683 G + A L+ + +GTFL+R+S+++ C +A SV IN + Sbjct: 29 YWGPLTVSAAHEKLKSEPEGTFLIRDSTQKNCFFAISVKTATGPTSIRINFQTGRFSLDG 88 Query: 684 PYNLYSSLKELVLHYQHTS 702 + L +L+ HY + Sbjct: 89 SKETFDCLFKLLEHYLSSP 107 >4JGH-A nrPDB Length = 173 Score = 98.6 bits (244), Expect = 9e-21, Method: Composition-based stats. Identities = 28/93 (30%), Positives = 48/93 (51%), Gaps = 8/93 (8%) Query: 323 NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIK 382 L WYWG ++ E EKL++ +GTFL+RD+S + T++++ ++ Sbjct: 13 KALRELGQTGWYWGSMTVNEAKEKLKEAPEGTFLIRDSSHSDY-LLTISVKTSAGPTNLR 71 Query: 383 IFHRDGKYGFSDPLT-------FSSVVELINHY 408 I ++DGK+ + F SVV LI++Y Sbjct: 72 IEYQDGKFRLDSIICVKSKLKQFDSVVHLIDYY 104 Score = 50.9 bits (120), Expect = 2e-06, Method: Composition-based stats. Identities = 21/84 (25%), Positives = 32/84 (38%), Gaps = 11/84 (13%) Query: 624 WNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCY--ACSVVVDGEVKHCVINKTATGYGF 681 W GS N+A+ L+ +GTFL+R+SS Y SV + I G Sbjct: 23 WYWGSMTVNEAKEKLKEAPEGTFLIRDSSHS-DYLLTISVKTSAGPTNLRIEYQ-DGKFR 80 Query: 682 A-------EPYNLYSSLKELVLHY 698 + S+ L+ +Y Sbjct: 81 LDSIICVKSKLKQFDSVVHLIDYY 104 >4XZ1-A nrPDB Length = 262 Score = 96.7 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 7/99 (7%) Query: 619 HDEKTWNVGSSNRNKAENLL--RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H+ W S R +AE L + DG FL+R +QG YA S++ V H +I++ Sbjct: 161 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDK 220 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLA 715 G + +L +LV + L D L L Sbjct: 221 AGKYCIPEGTKFDTLWQLVEY-----LKLKADGLIYCLK 254 Score = 69.3 bits (168), Expect = 6e-12, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 5/82 (6%) Query: 329 QDAEWYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKI-FH 385 + WY ++REE KL A DG FL+R + G Y L+L G I Sbjct: 162 ERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQ--GTYALSLIYGKTVYHYLISQD 219 Query: 386 RDGKYGFSDPLTFSSVVELINH 407 + GKY + F ++ +L+ + Sbjct: 220 KAGKYCIPEGTKFDTLWQLVEY 241 Score = 62.0 bits (149), Expect = 9e-10, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 8/103 (7%) Query: 623 TWNVGSSNRNKAENLLR--GKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVINKTATGY 679 + GS +R +AE L+ G DG FL+R+ + G Y S+V D H I + G Sbjct: 12 PFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGT 71 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 + EL Y + D L L P Sbjct: 72 YAIAGGKAHCGPAELCEFYS-----RDPDGLPCNLRKPCNRPS 109 Score = 52.8 bits (125), Expect = 6e-07, Method: Composition-based stats. Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 9/102 (8%) Query: 332 EWYWGDISREEVNE--KLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR-DG 388 +++G ISR E E KL ADG FL+R + G Y L+L I + +G Sbjct: 12 PFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGG-YVLSLVHDVRFHHFPIERQLNG 70 Query: 389 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 430 Y + EL Y + L L P ++ Sbjct: 71 TYAIAGGKAHCGPAELCEFYSRD-----PDGLPCNLRKPCNR 107 >4GL9-E nrPDB Length = 143 Score = 96.7 bits (239), Expect = 4e-20, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 +N LQ++ +YW ++ E N L GTFL+RD+S + H +TL+++ K + Sbjct: 19 VNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRH-FFTLSVKTQSGTKNL 77 Query: 382 KIFHRDGKYGFSD-------PLTFSSVVELINHY 408 +I G + F V++L++HY Sbjct: 78 RIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 111 Score = 47.0 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 7/86 (8%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVINKTATG 678 E + + +A LL + GTFL+R+SS Q + SV K+ I Sbjct: 26 QESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGS 85 Query: 679 Y------GFAEPYNLYSSLKELVLHY 698 + +P + + +LV HY Sbjct: 86 FSLQSDPRSTQPVPRFDCVLKLVHHY 111 >2OZO-A nrPDB Length = 613 Score = 96.3 bits (238), Expect = 4e-20, Method: Composition-based stats. Identities = 28/99 (28%), Positives = 42/99 (42%), Gaps = 7/99 (7%) Query: 619 HDEKTWNVGSSNRNKAENLL--RGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 H+ W S R +AE L + DG FL+R +QG YA S++ V H +I++ Sbjct: 158 HERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQGTYALSLIYGKTVYHYLISQDK 217 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLA 715 G + +L +LV + L D L L Sbjct: 218 AGKYCIPEGTKFDTLWQLVEY-----LKLKADGLIYCLK 251 Score = 68.6 bits (166), Expect = 8e-12, Method: Composition-based stats. Identities = 24/82 (29%), Positives = 37/82 (45%), Gaps = 5/82 (6%) Query: 329 QDAEWYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKI-FH 385 + WY ++REE KL A DG FL+R + G Y L+L G I Sbjct: 159 ERMPWYHSSLTREEAERKLYSGAQTDGKFLLRPRKEQ--GTYALSLIYGKTVYHYLISQD 216 Query: 386 RDGKYGFSDPLTFSSVVELINH 407 + GKY + F ++ +L+ + Sbjct: 217 KAGKYCIPEGTKFDTLWQLVEY 238 Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 27/103 (26%), Positives = 38/103 (36%), Gaps = 8/103 (7%) Query: 623 TWNVGSSNRNKAENLLR--GKRDGTFLVRESSKQ-GCYACSVVVDGEVKHCVINKTATGY 679 + GS +R +AE L+ G DG FL+R+ + G Y S+V D H I + G Sbjct: 9 PFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGGYVLSLVHDVRFHHFPIERQLNGT 68 Query: 680 GFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 + EL Y + D L L P Sbjct: 69 YAIAGGKAHCGPAELCEFYS-----RDPDGLPCNLRKPCNRPS 106 Score = 52.4 bits (124), Expect = 8e-07, Method: Composition-based stats. Identities = 27/102 (26%), Positives = 39/102 (38%), Gaps = 9/102 (8%) Query: 332 EWYWGDISREEVNE--KLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR-DG 388 +++G ISR E E KL ADG FL+R + G Y L+L I + +G Sbjct: 9 PFFYGSISRAEAEEHLKLAGMADGLFLLRQCLRSLGG-YVLSLVHDVRFHHFPIERQLNG 67 Query: 389 KYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 430 Y + EL Y + L L P ++ Sbjct: 68 TYAIAGGKAHCGPAELCEFYSRD-----PDGLPCNLRKPCNR 104 >2HMH-A nrPDB Length = 152 Score = 95.5 bits (236), Expect = 7e-20, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 +N LQ++ +YW ++ E N L GTFL+RD+S + H +TL+++ K + Sbjct: 25 VNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRH-FFTLSVKTQSGTKNL 83 Query: 382 KIFHRDGKYGFSD-------PLTFSSVVELINHY 408 +I G + F V++L++HY Sbjct: 84 RIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 117 Score = 46.2 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 7/86 (8%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVINKTATG 678 E + + +A LL + GTFL+R+SS Q + SV K+ I Sbjct: 32 QESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGS 91 Query: 679 Y------GFAEPYNLYSSLKELVLHY 698 + +P + + +LV HY Sbjct: 92 FSLQSDPRSTQPVPRFDCVLKLVHHY 117 >2BBU-A nrPDB Length = 164 Score = 93.6 bits (231), Expect = 2e-19, Method: Composition-based stats. Identities = 26/94 (27%), Positives = 46/94 (48%), Gaps = 8/94 (8%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 +N LQ++ +YW ++ E N L GTFL+RD+S + H +TL+++ K + Sbjct: 14 VNAVRKLQESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRH-FFTLSVKTQSGTKNL 72 Query: 382 KIFHRDGKYGFSD-------PLTFSSVVELINHY 408 +I G + F V++L++HY Sbjct: 73 RIQCEGGSFSLQSDPRSTQPVPRFDCVLKLVHHY 106 Score = 45.5 bits (106), Expect = 8e-05, Method: Composition-based stats. Identities = 21/86 (24%), Positives = 34/86 (39%), Gaps = 7/86 (8%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGC-YACSVVVDGEVKHCVINKTATG 678 E + + +A LL + GTFL+R+SS Q + SV K+ I Sbjct: 21 QESGFYWSAVTGGEANLLLSAEPAGTFLIRDSSDQRHFFTLSVKTQSGTKNLRIQCEGGS 80 Query: 679 Y------GFAEPYNLYSSLKELVLHY 698 + +P + + +LV HY Sbjct: 81 FSLQSDPRSTQPVPRFDCVLKLVHHY 106 >3EAP-A nrPDB Length = 271 Score = 93.6 bits (231), Expect = 3e-19, Method: Composition-based stats. Identities = 33/162 (20%), Positives = 64/162 (39%), Gaps = 8/162 (4%) Query: 128 APPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDC-DTPSVDLEMIDVHVLADAF 186 P L+ ++E + L+R S + L+ L + D L +A Sbjct: 83 IPSFLVDACTSLEDH-IHTEGLFRKSGS--VIRLKALKNKVDHGEGCLSSAPPCDIAGLL 139 Query: 187 KRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLKH 246 K++ +LP P++PA ++ ++ + L+ S + L+Y Sbjct: 140 KQFFRELPEPILPADLHEALLKAQQLGTEEKNKAT----LLLSCLLADHTVHVLRYFFNF 195 Query: 247 FFKLSQTSSKNLLNARVLSEIFSPMLFRFSAASSDNTENLIK 288 +S SS+N +++ L+ IF+P L + S + N K Sbjct: 196 LRNVSLRSSENKMDSSNLAVIFAPNLLQTSEGHEKMSSNTEK 237 >3MSX-B nrPDB Length = 201 Score = 91.3 bits (225), Expect = 1e-18, Method: Composition-based stats. Identities = 45/204 (22%), Positives = 91/204 (44%), Gaps = 14/204 (6%) Query: 99 PGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLECSTLYRTQSSSNL 158 P S + + ++LP++ E D P ++ ++ + +KG ++R ++ Sbjct: 1 PSSPTSPMPGQLFGISLPNICEN----DNLPKPVLDMLFFLNQKGPLTKGIFRQSANVKS 56 Query: 159 -AELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLDLPNPVIPAAVYSEMISLAPEVQSSE 217 EL++ L+ V L+ + V+A K +L ++P + + +Y +S+ + E Sbjct: 57 CRELKEKLNS-GVEVHLDCESIFVIASVLKDFLRNIPGSIFSSDLYDHWVSVMDQGND-E 114 Query: 218 EYIQLLKKLIRSPSIPHQYWLTLQYLLKHFFKLSQTSSKNLLNARVLSEIFSPMLFRFSA 277 E I +++L+ +P + L+YL + Q SS N + A L+ +P + A Sbjct: 115 EKINTVQRLLDQ--LPRANVVLLRYLFGVLHNIEQHSSSNQMTAFNLAVCVAPSILWPPA 172 Query: 278 ASSDNTENLIK-----VIEILIST 296 +SS EN +I+ LI Sbjct: 173 SSSPELENEFTKKVSLLIQFLIEN 196 >2LQW-A nrPDB Length = 303 Score = 89.4 bits (220), Expect = 5e-18, Method: Composition-based stats. Identities = 34/140 (24%), Positives = 55/140 (39%), Gaps = 17/140 (12%) Query: 322 MNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 S + WY G +SR+E +L+ G FLVRD+ST GDY L++ + Sbjct: 3 SARFDSSDRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSST-CPGDYVLSVSENSRVSHY 61 Query: 382 KIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQV----- 436 I + F + L+ Y+ L L+ P +Y + Sbjct: 62 IINSLPNRRFKIGDQEFDHLPALLEFYKIHYLDT------TTLIEPAPRYPSPPMGSVSA 115 Query: 437 ----VKEDNIEAVGKKLHEY 452 EDN+E V + L+++ Sbjct: 116 PNLPTAEDNLEYV-RTLYDF 134 Score = 88.2 bits (217), Expect = 1e-17, Method: Composition-based stats. Identities = 27/85 (31%), Positives = 39/85 (45%), Gaps = 2/85 (2%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATG 678 D W +G +R +A+ L+G+R G FLVR+SS G Y SV + V H +IN Sbjct: 10 DRSAWYMGPVSRQEAQTRLQGQRHGMFLVRDSSTCPGDYVLSVSENSRVSHYIINSLPNR 69 Query: 679 YGFAEPYNLYSSLKELVLHYQHTSL 703 + L L+ Y+ L Sbjct: 70 RFKIGDQ-EFDHLPALLEFYKIHYL 93 Score = 32.8 bits (73), Expect = 0.59, Method: Composition-based stats. Identities = 34/138 (24%), Positives = 50/138 (36%), Gaps = 40/138 (28%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 R LYD+ ED+ G+IL + + +PEE W + N+ G G Sbjct: 129 RTLYDFPGNDAEDLPFKKGEILVIIE--------------KPEE-QWWSARNK-DGRVGM 172 Query: 69 FPGTYVEYIGRKKISP--------------PTP-----KPRPPRPLPV---APGSSKTEA 106 P YVE + R SP P P +P+ PLP +PG++ T Sbjct: 173 IPVPYVEKLVRS--SPHGKHGNRNSNSYGIPEPAHAYAQPQTTTPLPAVSGSPGAAITPL 230 Query: 107 DVEQQALTLPDLAEQFAP 124 Q ++ P Sbjct: 231 PSTQNGPVFAKAIQKRVP 248 >6C5X-D nrPDB Length = 164 Score = 87.8 bits (216), Expect = 2e-17, Method: Composition-based stats. Identities = 25/116 (21%), Positives = 49/116 (42%), Gaps = 2/116 (1%) Query: 323 NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIK 382 + L +YWG + ++KL+ GTFL+RD+ K + + ++++ I+ Sbjct: 22 KTSSMLDTCGFYWGPMDVNVAHDKLKSEPIGTFLIRDSKQK-NCFFAISVKTARETVSIR 80 Query: 383 IFHRDGKYGFS-DPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVV 437 I GK+ FS + +L+ HY L L P+ + + ++ Sbjct: 81 IKFHAGKFSLDGSKELFSCLFQLVEHYMTSPKKMLVSPLRKVRLRPLQELCRKSIL 136 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 27/101 (26%), Positives = 42/101 (41%), Gaps = 1/101 (0%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESSKQGCY-ACSVVVDGEVKHCVINKTATGYGFAE 683 G + N A + L+ + GTFL+R+S ++ C+ A SV E I A + Sbjct: 33 YWGPMDVNVAHDKLKSEPIGTFLIRDSKQKNCFFAISVKTARETVSIRIKFHAGKFSLDG 92 Query: 684 PYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQRR 724 L+S L +LV HY + L P+ R+ Sbjct: 93 SKELFSCLFQLVEHYMTSPKKMLVSPLRKVRLRPLQELCRK 133 >2EYZ-A nrPDB Length = 304 Score = 84.4 bits (207), Expect = 2e-16, Method: Composition-based stats. Identities = 39/156 (25%), Positives = 64/156 (41%), Gaps = 29/156 (18%) Query: 323 NNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIK 382 N S + + WYWG +SR+E L+ G FLVRD+ST GDY L++ + Sbjct: 3 GNFDSEERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTS-PGDYVLSVSENSRVSHYI 61 Query: 383 IFH------------------RDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKL 424 I + D F S+ L+ Y+ L L Sbjct: 62 INSSGPRPPVPPSPAQPPPGVSPSRLRIGDQE-FDSLPALLEFYKIHYLDT------TTL 114 Query: 425 LYPVSKYQQDQ--VVKEDNIEAVGKKLHEYNTQFQE 458 + PVS+ +Q +++++ E V + L ++N +E Sbjct: 115 IEPVSRSRQGSGVILRQEEAEYV-RALFDFNGNDEE 149 Score = 81.3 bits (199), Expect = 1e-15, Method: Composition-based stats. Identities = 32/121 (26%), Positives = 47/121 (38%), Gaps = 23/121 (19%) Query: 620 DEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATG 678 + +W G +R +A LL+G+R G FLVR+SS G Y SV + V H +IN + Sbjct: 9 ERSSWYWGRLSRQEAVALLQGQRHGVFLVRDSSTSPGDYVLSVSENSRVSHYIINSSGPR 68 Query: 679 YGFAEPY----------------NLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 + SL L+ Y+ L TL PV + Sbjct: 69 PPVPPSPAQPPPGVSPSRLRIGDQEFDSLPALLEFYKIHYLDT------TTLIEPVSRSR 122 Query: 723 R 723 + Sbjct: 123 Q 123 Score = 36.2 bits (82), Expect = 0.053, Method: Composition-based stats. Identities = 34/121 (28%), Positives = 44/121 (36%), Gaps = 29/121 (23%) Query: 4 EGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETT 63 E RAL+D+ EED+ GDIL + +PEE W ++ Sbjct: 133 EAEYVRALFDFNGNDEEDLPFKKGDILRIRD--------------KPEEQWW--NAEDSE 176 Query: 64 GERGDFPGTYVEYI------------GRKKISPPTPKPRPPRPLPVAPGSSKTEADVEQQ 111 G+RG P YVE G ++ S P P P P P A S T Q Sbjct: 177 GKRGMIPVPYVEKYRPASASVSALIGGNQEGSHPQPLG-GPEPGPYAQPSVNTPLPNLQN 235 Query: 112 A 112 Sbjct: 236 G 236 >4H1O-A nrPDB Length = 560 Score = 77.8 bits (190), Expect = 2e-14, Method: Composition-based stats. Identities = 32/98 (32%), Positives = 48/98 (48%), Gaps = 4/98 (4%) Query: 624 WNVGSSNRNKAENLLRGK-RDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATGYGF 681 W + +AENLL + DG+FL R S S G + SV +G V H I T GY Sbjct: 27 WFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG-GYYD 85 Query: 682 AEPYNLYSSLKELVLHY-QHTSLVQHNDSLNVTLAYPV 718 +++L ELV +Y +H ++ + + L YP+ Sbjct: 86 LYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 123 Score = 77.4 bits (189), Expect = 2e-14, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 61/155 (39%), Gaps = 20/155 (12%) Query: 333 WYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKG----------GNNKLI 381 W+ G +S +E + L + G+FLVR++ GD+ L++R G + Sbjct: 133 WFHGHLSGKEAEKLLTEKGKHGSFLVRES-QSHPGDFVLSVRTGDDKGESNDGKSKVTHV 191 Query: 382 KIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDN 441 I ++ KY F S+ +L+ HY+ + + L L +Q N Sbjct: 192 MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVET---LGTVLQ-----LKQPLNTTRIN 243 Query: 442 IEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQE 476 + ++ E + + + +EE+ Q+ Sbjct: 244 AAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQ 278 Score = 75.5 bits (184), Expect = 9e-14, Method: Composition-based stats. Identities = 27/106 (25%), Positives = 49/106 (46%), Gaps = 3/106 (2%) Query: 325 NMSLQDAEWYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKI 383 + W+ +I+ E L DG+FL R + + GD+TL++R+ G IKI Sbjct: 19 FQGMTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSN-PGDFTLSVRRNGAVTHIKI 77 Query: 384 FHRDGKYGFSDPLTFSSVVELINHY-RNESLAQYNPKLDVKLLYPV 428 + G Y F+++ EL+ +Y + + ++L YP+ Sbjct: 78 QNTGGYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPL 123 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 14/107 (13%) Query: 624 WNVGSSNRNKAENLLRGK-RDGTFLVRES-SKQGCYACSVVV----------DGEVKHCV 671 W G + +AE LL K + G+FLVRES S G + SV +V H + Sbjct: 133 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 192 Query: 672 INKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 I + + SL +LV HY+ +V+ + L P+ Sbjct: 193 I-RCQELKYDVGGGERFDSLTDLVEHYKKNPMVETL-GTVLQLKQPL 237 >4E93-A nrPDB Length = 377 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 6/103 (5%) Query: 328 LQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRD 387 L + WY G I R EV E L G FLVR++ K +Y L++ G + I D Sbjct: 10 LHEQLWYHGAIPRAEVAELL--VHSGDFLVRESQGKQ--EYVLSVLWDGLPRHFIIQSLD 65 Query: 388 GKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 430 Y + F S+ LI+H + K V L V K Sbjct: 66 NLYRL-EGEGFPSIPLLIDHLLSTQQ-PLTKKSGVVLHRAVPK 106 Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 29/99 (29%), Positives = 40/99 (40%), Gaps = 6/99 (6%) Query: 617 PHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTA 676 P H+ + W G+ R + LL G FLVRES + Y SV+ DG +H +I Sbjct: 9 PLHE-QLWYHGAIPRAEVAELLVH--SGDFLVRESQGKQEYVLSVLWDGLPRHFIIQSLD 65 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLA 715 Y + S+ L+ H T S V L Sbjct: 66 NLYRLEGEG--FPSIPLLIDHLLSTQQPLTKKS-GVVLH 101 >6CMQ-A nrPDB Length = 427 Score = 77.0 bits (188), Expect = 2e-14, Method: Composition-based stats. Identities = 31/155 (20%), Positives = 61/155 (39%), Gaps = 20/155 (12%) Query: 333 WYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKG----------GNNKLI 381 W+ G +S +E + L + G+FLVR++ GD+ L++R G + Sbjct: 10 WFHGHLSGKEAEKLLTEKGKHGSFLVRES-QSHPGDFVLSVRTGDDKGESNDGKSKVTHV 68 Query: 382 KIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDN 441 I ++ KY F S+ +L+ HY+ + + L L +Q N Sbjct: 69 MIRCQELKYDVGGGERFDSLTDLVEHYKKNPMVET---LGTVLQ-----LKQPLNTTRIN 120 Query: 442 IEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQE 476 + ++ E + + + +EE+ Q+ Sbjct: 121 AAEIESRVRELSKLAETTDKVKQGFWEEFETLQQQ 155 Score = 70.5 bits (171), Expect = 3e-12, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 14/107 (13%) Query: 624 WNVGSSNRNKAENLLRGK-RDGTFLVRES-SKQGCYACSVVV----------DGEVKHCV 671 W G + +AE LL K + G+FLVRES S G + SV +V H + Sbjct: 10 WFHGHLSGKEAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVM 69 Query: 672 INKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPV 718 I + + SL +LV HY+ +V+ + L P+ Sbjct: 70 I-RCQELKYDVGGGERFDSLTDLVEHYKKNPMVETL-GTVLQLKQPL 114 >2B3O-A nrPDB Length = 532 Score = 75.9 bits (185), Expect = 6e-14, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 333 WYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYG 391 W+ D+S + L+ G+FL R + K GD++L++R G I+I + Y Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSR-KNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 392 FSDPLTFSSVVELINHY-RNESLAQYNPKLDVKLLYPV 428 F+++ EL+ +Y + + + Q + L YP+ Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL 100 Score = 74.0 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 34/160 (21%), Positives = 66/160 (41%), Gaps = 13/160 (8%) Query: 333 WYWGDISREEVNEKLRDTADG-TFLVRDASTKMHGDYTLTLRKG---------GNNKLIK 382 WY G +S + L+ + TFLVR++ ++ GD+ L++ IK Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQ-PGDFVLSVLSDQPKAGPGSPLRVTHIK 168 Query: 383 IFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNI 442 + G+Y TF S+ +L+ H++ + + V L P + + E+ + Sbjct: 169 VMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEA-SGAFVYLRQPYYATRVNAADIENRV 227 Query: 443 EAVGKKLHEYNTQFQEKSREYDRLY-EEYTRTSQEIQMKR 481 + KK +T E++ L +E Q ++ +R Sbjct: 228 LELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQR 267 Score = 72.8 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Query: 624 WNVGSSNRNKAENLLRGK-RDGTFLVR-ESSKQGCYACSVVVDGEVKHCVINKTATGYGF 681 W + AE LL+G+ G+FL R QG ++ SV V +V H I + + Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGD-FYD 62 Query: 682 AEPYNLYSSLKELVLHY-QHTSLVQHNDSLNVTLAYPV 718 +++L ELV +Y Q ++Q D + L YP+ Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL 100 Score = 70.1 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 28/171 (16%) Query: 571 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKT------- 623 I+++ + D Y ++ +K +L E+ Q +++D + H + Sbjct: 52 IRIQNSGDFYDLYGGEKFATLTELVEYY-----TQQQGVLQDRDGTIIHLKYPLNCSDPT 106 Query: 624 ---WNVGSSNRNKAENLLRGKRDG-TFLVRES-SKQGCYACSVVVDG---------EVKH 669 W G + +AE LL+ K + TFLVRES S+ G + SV+ D V H Sbjct: 107 SERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTH 166 Query: 670 CVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 + G + SL +LV H++ T + + V L P YA Sbjct: 167 IKVMCEG-GRYTVGGLETFDSLTDLVEHFKKTGI-EEASGAFVYLRQPYYA 215 >4M4Z-A nrPDB Length = 170 Score = 74.7 bits (182), Expect = 1e-13, Method: Composition-based stats. Identities = 25/86 (29%), Positives = 41/86 (47%), Gaps = 9/86 (10%) Query: 331 AEWYWGDISREEVNEKLRDTAD--GTFLVRDASTKMHGDYTLTLRKG-----GNNKLIKI 383 W + +SRE+ E L + G FL+R++ T+ G Y+L++R + +I Sbjct: 69 HGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRR-GSYSLSVRLSRPASWDRIRHYRI 127 Query: 384 FHRDGK-YGFSDPLTFSSVVELINHY 408 D S LTF S+ L++HY Sbjct: 128 HCLDNGWLYISPRLTFPSLQALVDHY 153 Score = 67.8 bits (164), Expect = 1e-11, Method: Composition-based stats. Identities = 27/87 (31%), Positives = 42/87 (48%), Gaps = 8/87 (9%) Query: 621 EKTWNVGSSNRNKAENLLRGKRD--GTFLVRES-SKQGCYACSVVVD-----GEVKHCVI 672 W +R KAE LL + G FL+RES +++G Y+ SV + ++H I Sbjct: 68 SHGWLYEGLSREKAEELLLLPGNPGGAFLIRESQTRRGSYSLSVRLSRPASWDRIRHYRI 127 Query: 673 NKTATGYGFAEPYNLYSSLKELVLHYQ 699 + G+ + P + SL+ LV HY Sbjct: 128 HCLDNGWLYISPRLTFPSLQALVDHYS 154 >3PS5-A nrPDB Length = 595 Score = 74.4 bits (181), Expect = 2e-13, Method: Composition-based stats. Identities = 25/98 (25%), Positives = 47/98 (47%), Gaps = 3/98 (3%) Query: 333 WYWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYG 391 W+ D+S + L+ G+FL R + K GD++L++R G I+I + Y Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSR-KNQGDFSLSVRVGDQVTHIRIQNSGDFYD 62 Query: 392 FSDPLTFSSVVELINHY-RNESLAQYNPKLDVKLLYPV 428 F+++ EL+ +Y + + + Q + L YP+ Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL 100 Score = 72.4 bits (176), Expect = 7e-13, Method: Composition-based stats. Identities = 34/160 (21%), Positives = 66/160 (41%), Gaps = 13/160 (8%) Query: 333 WYWGDISREEVNEKLRDTADG-TFLVRDASTKMHGDYTLTLRKG---------GNNKLIK 382 WY G +S + L+ + TFLVR++ ++ GD+ L++ IK Sbjct: 110 WYHGHMSGGQAETLLQAKGEPWTFLVRESLSQ-PGDFVLSVLSDQPKAGPGSPLRVTHIK 168 Query: 383 IFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNI 442 + G+Y TF S+ +L+ H++ + + V L P + + E+ + Sbjct: 169 VMCEGGRYTVGGLETFDSLTDLVEHFKKTGIEEA-SGAFVYLRQPYYATRVNAADIENRV 227 Query: 443 EAVGKKLHEYNTQFQEKSREYDRLY-EEYTRTSQEIQMKR 481 + KK +T E++ L +E Q ++ +R Sbjct: 228 LELNKKQESEDTAKAGFWEEFESLQKQEVKNLHQRLEGQR 267 Score = 71.3 bits (173), Expect = 1e-12, Method: Composition-based stats. Identities = 29/98 (29%), Positives = 46/98 (46%), Gaps = 4/98 (4%) Query: 624 WNVGSSNRNKAENLLRGK-RDGTFLVR-ESSKQGCYACSVVVDGEVKHCVINKTATGYGF 681 W + AE LL+G+ G+FL R QG ++ SV V +V H I + + Sbjct: 4 WFHRDLSGLDAETLLKGRGVHGSFLARPSRKNQGDFSLSVRVGDQVTHIRIQNSGD-FYD 62 Query: 682 AEPYNLYSSLKELVLHY-QHTSLVQHNDSLNVTLAYPV 718 +++L ELV +Y Q ++Q D + L YP+ Sbjct: 63 LYGGEKFATLTELVEYYTQQQGVLQDRDGTIIHLKYPL 100 Score = 68.2 bits (165), Expect = 1e-11, Method: Composition-based stats. Identities = 42/171 (24%), Positives = 70/171 (40%), Gaps = 28/171 (16%) Query: 571 IQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYSLVEDDEDLPHHDEKT------- 623 I+++ + D Y ++ +K +L E+ Q +++D + H + Sbjct: 52 IRIQNSGDFYDLYGGEKFATLTELVEYY-----TQQQGVLQDRDGTIIHLKYPLNCSDPT 106 Query: 624 ---WNVGSSNRNKAENLLRGKRDG-TFLVRES-SKQGCYACSVVVDG---------EVKH 669 W G + +AE LL+ K + TFLVRES S+ G + SV+ D V H Sbjct: 107 SERWYHGHMSGGQAETLLQAKGEPWTFLVRESLSQPGDFVLSVLSDQPKAGPGSPLRVTH 166 Query: 670 CVINKTATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 + G + SL +LV H++ T + + V L P YA Sbjct: 167 IKVMCEG-GRYTVGGLETFDSLTDLVEHFKKTGI-EEASGAFVYLRQPYYA 215 >1MIL-A nrPDB Length = 104 Score = 73.2 bits (178), Expect = 4e-13, Method: Composition-based stats. Identities = 30/107 (28%), Positives = 49/107 (45%), Gaps = 4/107 (3%) Query: 325 NMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIF 384 L+ W+ G +SR E L+ +G FLVR++ T G Y LT + G K + + Sbjct: 1 GSQLRGEPWFHGKLSRREAEALLQL--NGDFLVRES-TTTPGQYVLTGLQSGQPKHLLLV 57 Query: 385 HRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKY 431 +G D F SV LI+++ + L + ++ L PV + Sbjct: 58 DPEGVVRTKD-HRFESVSHLISYHMDNHLPIISAGSELCLQQPVERK 103 Score = 70.5 bits (171), Expect = 2e-12, Method: Composition-based stats. Identities = 26/100 (26%), Positives = 45/100 (45%), Gaps = 5/100 (5%) Query: 623 TWNVGSSNRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDGEVKHCVINKTATGYGF 681 W G +R +AE LL + +G FLVRES + G Y + + G+ KH ++ G Sbjct: 8 PWFHGKLSRREAEALL--QLNGDFLVRESTTTPGQYVLTGLQSGQPKH-LLLVDPEGVVR 64 Query: 682 AEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQ 721 + + S+ L+ ++ L + + L PV + Sbjct: 65 -TKDHRFESVSHLISYHMDNHLPIISAGSELCLQQPVERK 103 >2AUG-A nrPDB Length = 126 Score = 72.8 bits (177), Expect = 5e-13, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 7/92 (7%) Query: 618 HHDEKTWNVGSSNRNKAENLLRGK--RDGTFLVRES-SKQGCYACSVVVDGEVKHCVI-- 672 H + W +R++A+ L+ + DG FLVR+S S + S+ ++KH I Sbjct: 22 IHRSQPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPKTFVLSMSHGQKIKHFQIIP 81 Query: 673 -NKTATGYGFAEPYN-LYSSLKELVLHYQHTS 702 + + + ++ L +LV YQ Sbjct: 82 VEDDGEMFHTLDDGHTRFTDLIQLVEFYQLNK 113 Score = 64.0 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 22/89 (24%), Positives = 38/89 (42%), Gaps = 8/89 (8%) Query: 331 AEWYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIF--HR 386 W+ ISR+E + DG FLVRD+ + + L++ G K +I Sbjct: 26 QPWFHHKISRDEAQRLIIQQGLVDGVFLVRDSQSNPK-TFVLSMSHGQKIKHFQIIPVED 84 Query: 387 DGKYG--FSDP-LTFSSVVELINHYRNES 412 DG+ D F+ +++L+ Y+ Sbjct: 85 DGEMFHTLDDGHTRFTDLIQLVEFYQLNK 113 >5U06-A nrPDB Length = 120 Score = 71.7 bits (174), Expect = 1e-12, Method: Composition-based stats. Identities = 23/92 (25%), Positives = 39/92 (42%), Gaps = 7/92 (7%) Query: 617 PHHDEKTWNVGSSNRNKAENLLRGK--RDGTFLVRESS-KQGCYACSVVVDGEVKHCVIN 673 H + W G +R +++ L+ + DG FLVRES + S+ +VKH +I Sbjct: 12 AIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQGFVLSLCHLQKVKHYLIL 71 Query: 674 -KTATGYGFAEP---YNLYSSLKELVLHYQHT 701 G + ++ L +LV +Q Sbjct: 72 PSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 103 Score = 67.8 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 45/102 (44%), Gaps = 9/102 (8%) Query: 318 ANNGMNNNMSLQDAE-WYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRK 374 +G + + ++ + W+ G ISREE + DG FLVR++ G + L+L Sbjct: 3 PASGTSLSAAIHRTQLWFHGRISREESQRLIGQQGLVDGLFLVRESQRNPQG-FVLSLCH 61 Query: 375 GGNNKLIKIF--HRDGKYGFS---DPLTFSSVVELINHYRNE 411 K I +G+ FS F+ +++L+ ++ Sbjct: 62 LQKVKHYLILPSEEEGRLYFSMDDGQTRFTDLLQLVEFHQLN 103 >2QV2-A nrPDB Length = 342 Score = 69.0 bits (167), Expect = 7e-12, Method: Composition-based stats. Identities = 52/212 (24%), Positives = 88/212 (41%), Gaps = 24/212 (11%) Query: 71 GTYVEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADV---EQQALTLPDLAEQFA-PPD 126 GT +E + R K RP R +PV E E+ L + L E + P Sbjct: 122 GTSLEALCRMK--------RPIREVPVTKLIDLEEDSFLEKEKSLLQMVPLDEGASERPL 173 Query: 127 IAPPLLIKLVEAIEKKGLECSTLYRTQSSSNLAELRQLLDC-DTPSVDLEMIDVHVLADA 185 P + LV+ + K L++T EL+Q++DC DT + H +A+A Sbjct: 174 QVPKEIWLLVDHLFKYACHQEDLFQTPGM--QEELQQIIDCLDTSIPETIPGSNHSVAEA 231 Query: 186 FKRYLLDLPNPVIPAAVYSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQYLLK 245 +L LP PVI +Y + A + + + I +P + +YL+ Sbjct: 232 LLIFLEALPEPVICYELYQRCLDSAYDPRICRQVIS---------QLPRCHRNVFRYLMA 282 Query: 246 HFFKLSQTSSKNLLNARVLSEIFSPMLFRFSA 277 +L + S N +NA +++ +F+ +L R Sbjct: 283 FLRELLKFSEYNSVNANMIATLFTSLLLRPPP 314 >1NRV-A nrPDB Length = 105 Score = 66.3 bits (160), Expect = 5e-11, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 40/92 (43%), Gaps = 7/92 (7%) Query: 618 HHDEKTWNVGSSNRNKAENLLRGK--RDGTFLVRES-SKQGCYACSVVVDGEVKHCVI-- 672 H + W G +R ++ +++ + DG FL+R+S S + ++ ++K+ I Sbjct: 1 IHRTQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKAFVLTLCHHQKIKNFQILP 60 Query: 673 -NKTATGYGFAEPYN-LYSSLKELVLHYQHTS 702 + + N +S L +LV YQ Sbjct: 61 CEDDGQTFFSLDDGNTKFSDLIQLVDFYQLNK 92 Score = 64.0 bits (154), Expect = 2e-10, Method: Composition-based stats. Identities = 25/90 (27%), Positives = 42/90 (46%), Gaps = 8/90 (8%) Query: 330 DAEWYWGDISREEVNEKLRDTA--DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIF--H 385 W+ G ISREE + ++ DG FL+RD+ + + LTL K +I Sbjct: 4 TQHWFHGRISREESHRIIKQQGLVDGLFLLRDSQSNPKA-FVLTLCHHQKIKNFQILPCE 62 Query: 386 RDGK--YGFSD-PLTFSSVVELINHYRNES 412 DG+ + D FS +++L++ Y+ Sbjct: 63 DDGQTFFSLDDGNTKFSDLIQLVDFYQLNK 92 >2CS0-A nrPDB Length = 119 Score = 65.9 bits (159), Expect = 7e-11, Method: Composition-based stats. Identities = 24/101 (23%), Positives = 37/101 (36%), Gaps = 5/101 (4%) Query: 623 TWNVGSSNRNKAENLLRGKRDGTFLVRESSKQGCYACSVVVDGEVKHCVINKTATGYGFA 682 W G+ +R AENLL + G+FL+R S Y S H ++ G Sbjct: 17 EWFHGAISREDAENLLESQPLGSFLIRVSHSHVGYTLSYKAQSSCCHFMVKLLDDGTFMI 76 Query: 683 E-PYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 ++SL LV +Q + + L P + Sbjct: 77 PGEKVAHTSLDALVTFHQQKPIEPRRE----LLTQPCRQKD 113 Score = 63.2 bits (152), Expect = 4e-10, Method: Composition-based stats. Identities = 20/81 (24%), Positives = 38/81 (46%), Gaps = 4/81 (4%) Query: 332 EWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHR-DGKY 390 EW+ G ISRE+ L G+FL+R + + H YTL+ + + + DG + Sbjct: 17 EWFHGAISREDAENLLESQPLGSFLIRVSHS--HVGYTLSYKAQSSCCHFMVKLLDDGTF 74 Query: 391 GFS-DPLTFSSVVELINHYRN 410 + + +S+ L+ ++ Sbjct: 75 MIPGEKVAHTSLDALVTFHQQ 95 >2IZV-A nrPDB Length = 187 Score = 64.3 bits (155), Expect = 2e-10, Method: Composition-based stats. Identities = 22/94 (23%), Positives = 44/94 (46%), Gaps = 5/94 (5%) Query: 334 YWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIFHRDGKYGFS 393 YWG + + L +GTFL+RD++ + + ++++ R+ + +I + + F Sbjct: 37 YWGVMDKYAAEALLEGKPEGTFLLRDSAQEDY-LFSVSFRRYSRSLHARIEQWNHNFSFD 95 Query: 394 --DPLTFSS--VVELINHYRNESLAQYNPKLDVK 423 DP F S + L+ HY++ S + L Sbjct: 96 AHDPCVFHSPDITGLLEHYKDPSACMFFEPLLST 129 Score = 56.2 bits (134), Expect = 5e-08, Method: Composition-based stats. Identities = 35/132 (26%), Positives = 54/132 (40%), Gaps = 10/132 (7%) Query: 598 LGNENTEDQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGTFLVRESSKQG-C 656 LG EN Q LV DL + G ++ AE LL GK +GTFL+R+S+++ Sbjct: 13 LGTENLYFQSMLVP---DLLQINNNPCYWGVMDKYAAEALLEGKPEGTFLLRDSAQEDYL 69 Query: 657 YACSVVVDGEVKHCVINKTATGYGFAEPYNL-YSS--LKELVLHYQHTSLVQHNDSLNVT 713 ++ S H I + + F + S + L+ HY+ S + L T Sbjct: 70 FSVSFRRYSRSLHARIEQWNHNFSFDAHDPCVFHSPDITGLLEHYKDPSACMFFEPLLST 129 Query: 714 ---LAYPVYAQQ 722 +P Q Sbjct: 130 PLIRTFPFSLQH 141 >1RPY-A nrPDB Length = 114 Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 23/106 (21%), Positives = 47/106 (44%), Gaps = 6/106 (5%) Query: 621 EKTWNVGSSNRNKAENLL---RGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTA 676 + W G+ +R KA L+ + G F++R+S G + G+ KH ++ Sbjct: 10 DYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSETRPGECVLTFNFQGKAKHLRLSLNG 69 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSL-VQHNDSLNVTLAYPVYAQ 721 G + + S+ +++ H+ + ++ S ++TL V AQ Sbjct: 70 HGQCHV-QHLWFQSVFDMLRHFHTHPIPLESGGSADITLRSYVRAQ 114 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 22/109 (20%), Positives = 44/109 (40%), Gaps = 5/109 (4%) Query: 321 GMNNNMSLQDAEWYWGDISREEVNEKLRDTA---DGTFLVRDASTKMHGDYTLTLRKGGN 377 G + + L D W+ G +SR + + + G F++R + T G+ LT G Sbjct: 1 GSHMELELSDYPWFHGTLSRVKAAQLVLAGGPRSHGLFVIRQSET-RPGECVLTFNFQGK 59 Query: 378 NKLIKIFHRDGKYGFSDPLTFSSVVELI-NHYRNESLAQYNPKLDVKLL 425 K +++ L F SV +++ + + + + D+ L Sbjct: 60 AKHLRLSLNGHGQCHVQHLWFQSVFDMLRHFHTHPIPLESGGSADITLR 108 >1KA6-A nrPDB Length = 128 Score = 61.6 bits (148), Expect = 1e-09, Method: Composition-based stats. Identities = 26/105 (24%), Positives = 44/105 (41%), Gaps = 12/105 (11%) Query: 625 NVGSSNRNKAEN-LLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATGYGFA 682 G +R E LL DG++L+R+S G Y V+ G + +++T TG A Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66 Query: 683 EP-----YNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYAQQ 722 E + +K L+ +Q + + + L YPV + Sbjct: 67 ETAPGVHKRYFRKIKNLISAFQK-----PDQGIVIPLQYPVEKKS 106 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 29/120 (24%), Positives = 47/120 (39%), Gaps = 19/120 (15%) Query: 334 YWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKI-FHRDGKYG 391 Y G ISRE + L T DG++L+RD+ + G Y L + G ++ G + Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESV-PGVYCLCVLYHGYIYTYRVSQTETGSWS 65 Query: 392 FSD-----PLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSKY------QQDQVVKED 440 F + LI + + + + + L YPV K Q ++ED Sbjct: 66 AETAPGVHKRYFRKIKNLI-----SAFQKPDQGIVIPLQYPVEKKSSARSTQGTTGIRED 120 >1M27-A nrPDB Length = 104 Score = 61.3 bits (147), Expect = 1e-09, Method: Composition-based stats. Identities = 26/103 (25%), Positives = 43/103 (41%), Gaps = 12/103 (11%) Query: 625 NVGSSNRNKAEN-LLRGKRDGTFLVRESSK-QGCYACSVVVDGEVKHCVINKTATGYGFA 682 G +R E LL DG++L+R+S G Y V+ G + +++T TG A Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESVPGVYCLCVLYHGYIYTYRVSQTETGSWSA 66 Query: 683 EP-----YNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 E + +K L+ +Q + + + L YPV Sbjct: 67 ETAPGVHKRYFRKIKNLISAFQK-----PDQGIVIPLQYPVEK 104 Score = 57.4 bits (137), Expect = 2e-08, Method: Composition-based stats. Identities = 26/104 (25%), Positives = 42/104 (40%), Gaps = 13/104 (12%) Query: 334 YWGDISREEVNEKLRDTA-DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKI-FHRDGKYG 391 Y G ISRE + L T DG++L+RD+ + G Y L + G ++ G + Sbjct: 7 YHGKISRETGEKLLLATGLDGSYLLRDSESV-PGVYCLCVLYHGYIYTYRVSQTETGSWS 65 Query: 392 FSD-----PLTFSSVVELINHYRNESLAQYNPKLDVKLLYPVSK 430 F + LI + + + + + L YPV K Sbjct: 66 AETAPGVHKRYFRKIKNLI-----SAFQKPDQGIVIPLQYPVEK 104 >2HDV-A nrPDB Length = 111 Score = 61.3 bits (147), Expect = 2e-09, Method: Composition-based stats. Identities = 22/95 (23%), Positives = 41/95 (43%), Gaps = 8/95 (8%) Query: 613 DEDLPHHDEKTWNVGSSNRNKAENLL---RGKRDGTFLVRESSK-QGCYACSVVVDGEVK 668 D+ L W G +R KA L+ G FLVR+S +G + G+ K Sbjct: 3 DQPLS---GYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRRGECVLTFNFQGKAK 59 Query: 669 HCVINKTATGYGFAEPYNLYSSLKELVLHYQHTSL 703 H ++ A G + + + S+ +++ H++ + Sbjct: 60 HLRLSLNAAGQCRVQHLH-FQSIFDMLEHFRVHPI 93 Score = 57.0 bits (136), Expect = 2e-08, Method: Composition-based stats. Identities = 21/85 (24%), Positives = 38/85 (44%), Gaps = 4/85 (4%) Query: 328 LQDAEWYWGDISREEVNEKLRDTA---DGTFLVRDASTKMHGDYTLTLRKGGNNKLIKIF 384 L W+ G +SR + + + + G FLVR + T+ G+ LT G K +++ Sbjct: 6 LSGYPWFHGMLSRLKAAQLVLEGGTGSHGVFLVRQSETRR-GECVLTFNFQGKAKHLRLS 64 Query: 385 HRDGKYGFSDPLTFSSVVELINHYR 409 L F S+ +++ H+R Sbjct: 65 LNAAGQCRVQHLHFQSIFDMLEHFR 89 >5NP2-A nrPDB Length = 61 Score = 50.1 bits (118), Expect = 4e-06, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 18/49 (36%), Gaps = 5/49 (10%) Query: 276 SAASSDNTENLI-----KVIEILISTEWNERQPAPALPPKPPKPTTVAN 319 AS DNT ++ +V+ + EW E Q P T N Sbjct: 13 FVASGDNTLSITKGEKLRVLGYNHNGEWCEAQTKNGQGWVPSNYITPVN 61 >3QWY-A nrPDB Length = 308 Score = 49.3 bits (116), Expect = 5e-06, Method: Composition-based stats. Identities = 25/113 (22%), Positives = 45/113 (39%), Gaps = 15/113 (13%) Query: 620 DEKTWNVGSSNRNKAENLLRGK--RDGTFLVRESSKQGCYACSVV---VDGEVKHCVINK 674 + +++ +R +A LL GTFL+R+SS+ G Y+ +V V H +I + Sbjct: 39 EWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDSSRPGEYSLTVREADEGNAVCHYLIER 98 Query: 675 -------TATGYGFAEPYNLYSSLKELVLHYQHTSLVQHNDSLNVTLAYPVYA 720 TA + + + L+ H++ L SL P+ Sbjct: 99 GEPKEDGTAAAGVKIANQS-FPDIPALLNHFKMRVL--TEASLLAAYKKPIIE 148 Score = 48.9 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 27/99 (27%), Positives = 46/99 (46%), Gaps = 14/99 (14%) Query: 323 NNNMSLQDAEWYWGDISREEVNEKLRDT--ADGTFLVRDASTKMHGDYTLTLR---KGGN 377 N + +Y+ +SREE ++ L + + GTFL+RD+S G+Y+LT+R +G Sbjct: 33 NGFDPFEWRSFYFPGMSREEAHKLLGEPQVSIGTFLMRDSS--RPGEYSLTVREADEGNA 90 Query: 378 NKLIKIF----HRDGKYGFS---DPLTFSSVVELINHYR 409 I DG +F + L+NH++ Sbjct: 91 VCHYLIERGEPKEDGTAAAGVKIANQSFPDIPALLNHFK 129 >2CR4-A nrPDB Length = 126 Score = 48.2 bits (113), Expect = 1e-05, Method: Composition-based stats. Identities = 23/111 (20%), Positives = 41/111 (36%), Gaps = 10/111 (9%) Query: 317 VANNGMNNNMSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGG 376 + +N S + + R E DG + +R++STK + Sbjct: 16 PNSVFVNTTESCEVERLFKATSPRGE-------PQDGLYCIRNSSTKSGKVLVVWDETSN 68 Query: 377 NNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDVKLLYP 427 + +IF +D K+ + F SV ++ HY L + L L +P Sbjct: 69 KVRNYRIFEKDSKFYLEGEVLFVSVGSMVEHYHTHVLPSHQSLL---LRHP 116 >6E11-1 nrPDB Length = 906 Score = 41.6 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 31/138 (22%), Positives = 67/138 (48%), Gaps = 6/138 (4%) Query: 430 KYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQM-----KRTAI 484 ++ +D+ + + I+ + K Q K R D + R S EI + + Sbjct: 408 RFIKDRYLPDKAIDLLNKACSFLQVQLSGKPRIIDVTERDIERLSYEISTLEKDVDKVSK 467 Query: 485 EAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKL-KSRISEIIDSRR 543 + +N+ IK FEE+ + ++Y +EY+ +R +KEI++ +++ +L ++ + + Sbjct: 468 KKYNKLIKEFEEKKEQLKKYYEEYVITGERLKRKKEIEKKLNDLKELTQNYVYSNKEPPI 527 Query: 544 RLEEDLKKQAAEYREIDK 561 L+ LK+ +Y E+ K Sbjct: 528 ELQNSLKEAQQKYLELYK 545 >2X3W-D nrPDB Length = 60 Score = 40.1 bits (92), Expect = 0.003, Method: Composition-based stats. Identities = 26/75 (34%), Positives = 37/75 (49%), Gaps = 15/75 (20%) Query: 3 AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNET 62 A+G + RALYDY + ++++ GD LT LG D Q GW G + Sbjct: 1 AKGVRVRALYDYDGQEQDELSFKAGDELT-------KLGEEDEQ-------GWCRGRLD- 45 Query: 63 TGERGDFPGTYVEYI 77 +G+ G +P YVE I Sbjct: 46 SGQLGLYPANYVEAI 60 >1UUS-A nrPDB Length = 473 Score = 39.3 bits (90), Expect = 0.005, Method: Composition-based stats. Identities = 17/89 (19%), Positives = 34/89 (38%), Gaps = 14/89 (15%) Query: 619 HDEKTW----NVGSSNRNKAENLLRGKRDGTFLVRESS-KQGCYACS---VVVDGEVKHC 670 H W G R + + L+ + GTF++R S G + + V + +KH Sbjct: 344 HISTLWQEGIIYGYMGRQEVNDALQNQDPGTFIIRFSERNPGQFGIAYIGVEMPARIKHY 403 Query: 671 VINKTATGYG------FAEPYNLYSSLKE 693 ++ T F ++ + +L + Sbjct: 404 LVQPNDTAAAKKTFPDFLSEHSQFVNLLQ 432 Score = 35.8 bits (81), Expect = 0.063, Method: Composition-based stats. Identities = 27/121 (22%), Positives = 45/121 (37%), Gaps = 10/121 (8%) Query: 326 MSLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLT---LRKGGNNKLIK 382 +L +G + R+EVN+ L++ GTF++R + G + + + K Sbjct: 346 STLWQEGIIYGYMGRQEVNDALQNQDPGTFIIRFSERN-PGQFGIAYIGVEMPARIKHYL 404 Query: 383 IFHRD---GKYGFSD-PLTFSSVVELINHYRNESLAQYNPKL--DVKLLYPVSKYQQDQV 436 + D K F D S V L+ ++ + A KL D L K Sbjct: 405 VQPNDTAAAKKTFPDFLSEHSQFVNLLQWTKDTNGAPRFLKLHKDTALGSFAPKRTAPVP 464 Query: 437 V 437 V Sbjct: 465 V 465 >3PVL-A nrPDB Length = 655 Score = 38.9 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 22/56 (39%), Positives = 28/56 (50%), Gaps = 3/56 (5%) Query: 30 LTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDFPGTYVEYIGRKKISPP 85 L+ KG L+ L G++ GW NG NE T +RGDFP V Y+ PP Sbjct: 593 LSFAKGDLIILDHDTGEQVMNS--GWANGINERTKQRGDFPTDCV-YVMPTVTLPP 645 >3PJP-A nrPDB Length = 199 Score = 38.5 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 8/92 (8%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESSKQGCY-ACSVVVDGEV-KHCVI------NKTA 676 N +AE+ LR K G F++R+SS+ + A + +D ++ +H I N A Sbjct: 12 YYFPFNGKQAEDYLRSKERGDFVIRQSSRGDDHLAITWKLDKDLFQHVDIQELEKENPLA 71 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHND 708 G Y L ++++ Y + N+ Sbjct: 72 LGKVLVVEGQRYHDLDQIIVEYLQNKIRLLNE 103 >5VKO-A nrPDB Length = 211 Score = 38.1 bits (87), Expect = 0.013, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 8/92 (8%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESSKQGCY-ACSVVVDGEV-KHCVI------NKTA 676 N +AE+ LR K G F++R+SS+ + + +D ++ +H I N A Sbjct: 18 YYFPFNGRQAEDYLRSKERGEFVIRQSSRGDDHLVITWKLDKDLFQHIDIQELEKENPLA 77 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHND 708 G Y+ L ++++ Y + N+ Sbjct: 78 LGKVLIVDNQKYNDLDQIIVEYLQNKVRLLNE 109 Score = 33.5 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 15/91 (16%), Positives = 34/91 (37%), Gaps = 10/91 (10%) Query: 331 AEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLTLRKGGNN-KLIKIFHRD-- 387 +Y+ + + + LR G F++R +S +T + + + I I + Sbjct: 16 HPYYF-PFNGRQAEDYLRSKERGEFVIRQSSRGDD-HLVITWKLDKDLFQHIDIQELEKE 73 Query: 388 -----GKYGFSDPLTFSSVVELINHYRNESL 413 GK D ++ + ++I Y + Sbjct: 74 NPLALGKVLIVDNQKYNDLDQIIVEYLQNKV 104 >3GXW-A nrPDB Length = 103 Score = 37.8 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 22/92 (23%), Positives = 40/92 (43%), Gaps = 8/92 (8%) Query: 625 NVGSSNRNKAENLLRGKRDGTFLVRESSKQGCY-ACSVVVDGEV-KHCVI------NKTA 676 N +AE+ LR K G F++R+SS+ + A + +D ++ +H I N A Sbjct: 12 YYFPFNGKQAEDYLRSKERGDFVIRQSSRGDDHLAITWKLDKDLFQHVDIQEMEKENPLA 71 Query: 677 TGYGFAEPYNLYSSLKELVLHYQHTSLVQHND 708 G Y L ++++ Y + N+ Sbjct: 72 MGKVLVVEGQRYHDLDQIIVEYLQNKIRLLNE 103 >3QOF-A nrPDB Length = 459 Score = 37.0 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 44/104 (42%), Gaps = 6/104 (5%) Query: 427 PVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEA 486 P K + +N+ AV YN + +E ++ +Q+K +++ Sbjct: 354 PHPKSMLQATAEANNLAAVATAKDTYNKKMEEICGGDKPFLAPNDLQTKHLQLKEESVKL 413 Query: 487 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDK 530 F K+ E+ +S+ Y+++ + E +E IQ I HN K Sbjct: 414 FRGVKKMGGEE------FSRRYLQQLESEIDELYIQYIKHNDSK 451 >2CUC-A nrPDB Length = 70 Score = 37.0 bits (84), Expect = 0.033, Method: Composition-based stats. Identities = 24/73 (32%), Positives = 33/73 (45%), Gaps = 17/73 (23%) Query: 3 AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALG-FSDGQEARPEEIGWLNGYNE 61 + G + AL+ Y R E++DL G+ + V LG + DG WL G + Sbjct: 5 SSGNMFVALHTYSAHRPEELDLQKGEGIRV-------LGKYQDG---------WLKGLSL 48 Query: 62 TTGERGDFPGTYV 74 TG G FP YV Sbjct: 49 LTGRTGIFPSDYV 61 >6F55-A nrPDB Length = 67 Score = 36.6 bits (83), Expect = 0.039, Method: Composition-based stats. Identities = 22/78 (28%), Positives = 33/78 (42%), Gaps = 15/78 (19%) Query: 1 MSAEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYN 60 M G + RALYDY + +++ G+ L + + +E GW G Sbjct: 1 MKVPGVRVRALYDYTGQEADELSFKAGEELM--------------KISEEDEQGWCKG-R 45 Query: 61 ETTGERGDFPGTYVEYIG 78 TG G +P YVE +G Sbjct: 46 LLTGHVGLYPANYVEKVG 63 >4RM9-A nrPDB Length = 587 Score = 36.2 bits (82), Expect = 0.047, Method: Composition-based stats. Identities = 39/183 (21%), Positives = 80/183 (43%), Gaps = 11/183 (6%) Query: 474 SQEIQMKR---TAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDK 530 + E+ M+R IE + EE+ Q Q + EK +RE E+E +++M ++ Sbjct: 288 NHELYMRRRKPDTIEVQQMKAQAREEKHQKQLERQQLETEKKRRETVEREKEQMMREKEE 347 Query: 531 LKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMW---LTQK 587 L R+ + + ++ E +L +Q ++++ + + +L R L L ++ Sbjct: 348 LMLRLQDYEEKTKKAERELSEQIQRALQLEEERKRAQEEAERLEADRMAALRAKEELERQ 407 Query: 588 GVRQKKLNEWLGNENTE--DQYSLVEDDEDLPHHDEKTWNVGSSNRNKAENLLRGKRDGT 645 V Q K E L E E + +L+E+ + + W + +A++ L ++ Sbjct: 408 AVDQIKSQEQLAAELAEYTAKIALLEEARRRKEDEVEEWQHRA---KEAQDDLVKTKEEL 464 Query: 646 FLV 648 LV Sbjct: 465 HLV 467 >2ED0-A nrPDB Length = 78 Score = 36.2 bits (82), Expect = 0.050, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 17/68 (25%) Query: 10 ALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDF 69 A+YDY K++E+++ G I+ V K + + GW G G G F Sbjct: 22 AIYDYTKDKEDELSFQEGAIIYVIKKN---------------DDGWYEGV--MNGVTGLF 64 Query: 70 PGTYVEYI 77 PG YVE I Sbjct: 65 PGNYVESI 72 >2ZR2-A nrPDB Length = 455 Score = 35.4 bits (80), Expect = 0.078, Method: Composition-based stats. Identities = 21/63 (33%), Positives = 36/63 (57%), Gaps = 4/63 (6%) Query: 519 KEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRD 578 KEI R+ H +K+ I + RR+ E + + A+ REI KR+ ++ ++ +L+K D Sbjct: 45 KEINRLRHERNKIAVEIGK----RRKKGEPVDELLAKSREIVKRIGELENEVEELKKKID 100 Query: 579 QYL 581 YL Sbjct: 101 YYL 103 >5XG2-A nrPDB Length = 260 Score = 35.4 bits (80), Expect = 0.095, Method: Composition-based stats. Identities = 29/104 (27%), Positives = 55/104 (52%), Gaps = 4/104 (3%) Query: 474 SQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNE--KEIQRIMHNYDKL 531 S E+++K + +E E + E+ +ER +E IE KR NE I+R KL Sbjct: 133 SFELRIKLSDLEKELELARKDLEKVLAEERAVREEIEVAKRRINELDTLIERERGELAKL 192 Query: 532 KSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRK 575 + RI + R +L++ L+ E RE+ +++ +++ ++ LR+ Sbjct: 193 RGRIERLERKRDKLKKALEN--PEARELTEKIRAVEKEIAALRE 234 >2XPY-A nrPDB Length = 632 Score = 35.4 bits (80), Expect = 0.095, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 48/123 (39%), Gaps = 6/123 (4%) Query: 203 YSEMISLAPEVQSSEEYIQLLKKLIRSPSIPHQYWLTLQY-----LLKHFFKLSQTSSKN 257 +S++ + ++ E + L++ L + P + T+ Y LL H + ++ Sbjct: 352 WSDLQNSIDSMKDPERFSTLVQNL-NDNTDPDDAFSTVPYEKGFNLLFHLETILGGKAEF 410 Query: 258 LLNARVLSEIFSPMLFRFSAASSDNTENLIKVIEILISTEWNERQPAPALPPKPPKPTTV 317 R + F+ E + EIL S +W P +PP+P T + Sbjct: 411 DPFIRHYFKKFAKKSLDTFQFLDTLYEFYPEKKEILDSVDWETWLYKPGMPPRPHFITAL 470 Query: 318 ANN 320 A+N Sbjct: 471 ADN 473 >6GYM-3 nrPDB Length = 321 Score = 35.1 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 32/160 (20%), Positives = 63/160 (39%), Gaps = 14/160 (8%) Query: 402 VELINHYRNESLAQYNPKLDVKLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQ-EKS 460 ++ + E ++ + + D V +E V +++ + K+ Sbjct: 70 TQIFDDVEVEKEVDIRKRVFNVFNKTIDDFNGDLVEYNKYLEEVEDIIYKLDHGIDVAKT 129 Query: 461 REYDRLYEEYTRT--SQEIQMKRTAIEAFNETIK----------IFEEQCQTQERYSKEY 508 E R YEE + ++ RT IE+F + K + E Q + +ER +KE+ Sbjct: 130 EEKLRTYEELNKQLIMNNLERSRTEIESFEQRQKFEKEMKLKKRLLERQIEEEERMNKEW 189 Query: 509 IEKFKREGNEKEIQRIMHNYDKLKSRIS-EIIDSRRRLEE 547 +K Q I + +K+ + + +RR+LEE Sbjct: 190 TKKEIVNRLSTTTQDINETIEGVKNTVKLKKSSARRKLEE 229 >4N78-F nrPDB Length = 514 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 22/68 (32%), Positives = 31/68 (45%), Gaps = 17/68 (25%) Query: 10 ALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGDF 69 A+YDY K++E+++ G I+ V K + + GW G G G F Sbjct: 459 AIYDYTKDKEDELSFQEGAIIYVIKKN---------------DDGWYEGV--MNGVTGLF 501 Query: 70 PGTYVEYI 77 PG YVE I Sbjct: 502 PGNYVESI 509 >1F5N-A nrPDB Length = 592 Score = 34.7 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 32/152 (21%), Positives = 65/152 (42%), Gaps = 9/152 (5%) Query: 363 KMHGDYTLTLRKGGNNKLIKIFHRDGKYGFSDPLTFSSVVELINHYRNESLAQYNPKLDV 422 G Y L ++K + K K ++ + + G + ++ ES+ + D Sbjct: 428 SKPGGYRLFVQKLQDLK--KKYYEEPRKGIQAEEILQTYLK-----SKESMTDAILQTDQ 480 Query: 423 KLLYPVSKYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRT 482 L K + + VK ++ +A K LHE + ++ + +R Y+E+ + E +M+ Sbjct: 481 TLTEK-EKEIEVERVKAESAQASAKMLHEMQRKNEQMMEQKERSYQEHLKQLTE-KMEND 538 Query: 483 AIEAFNETIKIFEEQCQTQERYSKEYIEKFKR 514 ++ E + + Q QE+ KE +K R Sbjct: 539 RVQLLKEQERTLALKLQEQEQLLKEGFQKESR 570 >5OFO-C nrPDB Length = 871 Score = 33.9 bits (76), Expect = 0.27, Method: Composition-based stats. Identities = 36/166 (21%), Positives = 72/166 (43%), Gaps = 31/166 (18%) Query: 430 KYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEY---------TRT-SQEIQM 479 K +Q ++KE + EA K+L N + +K R+Y L EE+ T+T E++ Sbjct: 427 KLEQQALMKESD-EASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQ 485 Query: 480 KRTAIEAFNET-------------IKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMH 526 + AIE I E+Q + + + + + + + EI ++ Sbjct: 486 AKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLA 545 Query: 527 NYDKLKSRISEIIDSRR----RLEEDLKKQAAEYRE-IDKRMNSIK 567 + + +S +++S R R+E++L + E +D N+I+ Sbjct: 546 RWTGIP--VSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIR 589 >1Y1U-A nrPDB Length = 585 Score = 33.5 bits (75), Expect = 0.31, Method: Composition-based stats. Identities = 21/57 (36%), Positives = 29/57 (50%), Gaps = 5/57 (8%) Query: 614 EDLPHHDEKTWNVGSS----NRNKAENLLRGKRDGTFLVRES-SKQGCYACSVVVDG 665 E L H + WN G+ N+ +A +LL K DGTFL+R S S+ G + D Sbjct: 452 EVLKKHHKPHWNDGAILGFVNKQQAHDLLINKPDGTFLLRFSDSEIGGITIAWKFDS 508 Score = 32.4 bits (72), Expect = 0.67, Method: Composition-based stats. Identities = 17/94 (18%), Positives = 34/94 (36%), Gaps = 10/94 (10%) Query: 294 ISTEWNERQPAPALPPKPPKPT--TVANNGMNNNMSLQDAEWYWGDI----SREEVNEKL 347 +S W++ T + M W G I ++++ ++ L Sbjct: 424 MSVSWSQFNRENLPGW---NYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQQAHDLL 480 Query: 348 RDTADGTFLVRDASTKMHGDYTLTLRKGGNNKLI 381 + DGTFL+R S G T+ + ++ + Sbjct: 481 INKPDGTFLLR-FSDSEIGGITIAWKFDSPDRNL 513 >2I1J-A nrPDB Length = 575 Score = 33.5 bits (75), Expect = 0.32, Method: Composition-based stats. Identities = 23/91 (25%), Positives = 46/91 (50%), Gaps = 7/91 (7%) Query: 495 EEQCQTQERYSKEYIEKFKREGNEKEIQ-------RIMHNYDKLKSRISEIIDSRRRLEE 547 EE+ Q + K +E RE EK+ Q ++ ++ ++ + E D RLEE Sbjct: 311 EEKLAKQAQREKLQLEIAARERAEKKQQEYQDRLRQMQEEMERSQANLLEAQDMILRLEE 370 Query: 548 DLKKQAAEYREIDKRMNSIKPDLIQLRKTRD 578 L++ A E+++R N ++ + +L +T++ Sbjct: 371 QLRQLQAAKEELEQRQNELQAMMQRLEETKN 401 >3EF1-A nrPDB Length = 442 Score = 33.1 bits (74), Expect = 0.39, Method: Composition-based stats. Identities = 38/180 (21%), Positives = 73/180 (40%), Gaps = 32/180 (17%) Query: 400 SVVELINHYRNESLAQYNPKLDVKLLYPVSKYQQ--DQVVKEDNIEAVGKKLHEYNTQFQ 457 ++++++ + + N K P+ + +Q + +D ++V +++E N Sbjct: 170 NLIKVVPYEFFVGIGDINSNFLAKST-PLPEQEQLIPLEIPKDEPDSV-DEINEEN---- 223 Query: 458 EKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKR--- 514 E++ EYD Y + S I K + F + + EE Q +ER + ++K +R Sbjct: 224 EETPEYDSSNSSYAQDSSTIPEKTLLKDTFLQNREALEE--QNKERVTALELQKSERPLA 281 Query: 515 ---------EGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNS 565 EG ++HN D RLE+ LK A Y E + ++S Sbjct: 282 KQQNALLEDEGKPTPSHTLLHNRDH----------ELERLEKVLKDIHAVYYEEENDISS 331 >1WXU-A nrPDB Length = 93 Score = 33.1 bits (74), Expect = 0.45, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 37/75 (49%), Gaps = 16/75 (21%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGY--NETTGER 66 RA YD+ +E+I GD+L +AL +E +P+ GWL +TTG Sbjct: 21 RAEYDFVAVSDEEISFRAGDMLN------LAL-----KEQQPKVRGWLLASLDGQTTGL- 68 Query: 67 GDFPGTYVEYIGRKK 81 P YV+ +G+++ Sbjct: 69 --IPANYVKILGKRR 81 >2M7L-A nrPDB Length = 144 Score = 32.8 bits (73), Expect = 0.54, Method: Composition-based stats. Identities = 23/80 (28%), Positives = 40/80 (50%), Gaps = 7/80 (8%) Query: 37 LVALGFSDGQEARPEEIGWLNGYNETT-GERGDFPGTYVEYIGRKKISPPTPKPRPPRPL 95 L+ + F+ G++A+ + I YN T GE G YV+Y+ K P+P+ Sbjct: 43 LIDIDFTGGEDAQYDAI-----YNNVTKGENGVSFDNYVQYMKEKNDENPSPEQLNEIFS 97 Query: 96 PVAPGS-SKTEADVEQQALT 114 +A G S TE D+++ ++ Sbjct: 98 TIAAGKDSITETDMQKAGMS 117 >3KZ4-A nrPDB Length = 880 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 28/116 (24%), Positives = 53/116 (45%), Gaps = 9/116 (7%) Query: 453 NTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKF 512 N + QEK E + + + K + E IKI +E ++ + SK+ +E Sbjct: 17 NDRMQEKDDEKQDQNNRMQLSDKVLSKKEEVVTDSQEEIKIADEVKKSTKEESKQLLEVL 76 Query: 513 K-REGNEKEI-----QRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKR 562 K +E ++KEI Q+ + ++ +S + ++ D + E KKQ +R + R Sbjct: 77 KTKEEHQKEIQYEILQKTIPTFEPKESILKKLEDIK---PEQAKKQTKLFRIFEPR 129 >1K4U-S nrPDB Length = 62 Score = 32.8 bits (73), Expect = 0.56, Method: Composition-based stats. Identities = 23/72 (31%), Positives = 33/72 (45%), Gaps = 17/72 (23%) Query: 4 EGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETT 63 +G Q AL+ Y+ + ED++ GDI+ V S E WL G E+ Sbjct: 4 KGSQVEALFSYEATQPEDLEFQEGDIILV---------LSKVNEE------WLEG--ESK 46 Query: 64 GERGDFPGTYVE 75 G+ G FP +VE Sbjct: 47 GKVGIFPKVFVE 58 >5YHJ-A nrPDB Length = 413 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 32/58 (55%), Gaps = 1/58 (1%) Query: 546 EEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENT 603 +E++ K+ E R + + S+ P +Q RK R +W+ Q V++ + N L NE+T Sbjct: 153 KEEVGKRTEEMRLLFESGTSLGPTYLQGRKARSSAEVWIRQM-VKEVRSNRLLPNEHT 209 >4U5I-A nrPDB Length = 403 Score = 32.8 bits (73), Expect = 0.61, Method: Composition-based stats. Identities = 16/31 (51%), Positives = 18/31 (58%), Gaps = 8/31 (25%) Query: 70 PGTYVEYIGRKKISP-PTPKPRPPRPLPVAP 99 PGTY Y SP P+P PRP +P PV P Sbjct: 380 PGTYPSY------SPKPSPTPRPTKP-PVTP 403 >2EFL-A nrPDB Length = 305 Score = 32.4 bits (72), Expect = 0.65, Method: Composition-based stats. Identities = 35/202 (17%), Positives = 78/202 (38%), Gaps = 42/202 (20%) Query: 447 KKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSK 506 K+ E + ++ R + Y+ + +E + K T+ +AF + + E S+ Sbjct: 38 KERTEIELSYAKQLRNLSKKYQPKKNSKEEEEYKYTSCKAFISNLNEMNDYAGQHEVISE 97 Query: 507 -----------EYIEKFKREGNEKEIQRIMHNYDKLKSRIS----EIIDSRRRLEEDLKK 551 Y+++ K+E H+ K + I ++ S+RR E D K+ Sbjct: 98 NMASQIIVDLARYVQELKQERKSN-----FHDGRKAQQHIETCWKQLESSKRRFERDCKE 152 Query: 552 --QAAEYRE-IDKRMNSIKPDLIQLRKTRDQYLMWLTQKGVRQKKLNEWLGNENTEDQYS 608 +A +Y E +D +N K D+ +K +Q ++ + ++ D S Sbjct: 153 ADRAQQYFEKMDADINVTKADV---------------EKARQQAQIRHQMAEDSKADYSS 197 Query: 609 LVEDDEDLPHHDEKTWNVGSSN 630 +++ +H++ + Sbjct: 198 ILQK----FNHEQHEYYHTHIP 215 >4BNE-A nrPDB Length = 457 Score = 32.4 bits (72), Expect = 0.74, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 32/69 (46%), Gaps = 15/69 (21%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 RALYDY+ + ++++ GD LT + +E GW G + G+ G Sbjct: 403 RALYDYEGQEQDELSFKAGDELT--------------KMENEDEQGWCKGRLD-NGQVGL 447 Query: 69 FPGTYVEYI 77 +P YVE I Sbjct: 448 YPANYVEPI 456 >5ZWN-S nrPDB Length = 298 Score = 32.0 bits (71), Expect = 0.86, Method: Composition-based stats. Identities = 30/152 (19%), Positives = 78/152 (51%), Gaps = 5/152 (3%) Query: 462 EYDRLYEEYTRTSQEIQMKRTAI-EAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKE 520 E DR E+YT T+ ++Q ++ + +A ++ + Q ++ + Y K+ ++ Sbjct: 86 EADRFLEKYTTTALKVQGRKVRMGKARTNSLLGLSIEMQKKKGNDETYNLDIKKVLKARK 145 Query: 521 IQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQY 580 ++R + + D + ++ + RRL+ L+ + E EID+ + + ++ K++ + Sbjct: 146 LKRKLRS-DDICAKKFRLKRQIRRLKHKLRSRKVEEAEIDRIVKEFETRRLENMKSQQEN 204 Query: 581 LMWLTQKGVRQKKLNEWLGNENTEDQYSLVED 612 L +QK +++ K++ + EN ++ L+++ Sbjct: 205 LKQ-SQKPLKRAKVSNTM--ENPPNKVLLIQN 233 >5FM1-B nrPDB Length = 846 Score = 32.0 bits (71), Expect = 0.89, Method: Composition-based stats. Identities = 17/65 (26%), Positives = 30/65 (46%), Gaps = 1/65 (1%) Query: 458 EKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSKEYIEKFKREGN 517 +K R Y+ L + I + RT + FN ++ + C +E + KE K +R N Sbjct: 615 KKIRGYNPLIRDIINKLSRISILRTQFQQFNSKMESYYLNCIIEENF-KEMTRKLQRTEN 673 Query: 518 EKEIQ 522 + + Q Sbjct: 674 KSQNQ 678 >1SPK-A nrPDB Length = 72 Score = 32.0 bits (71), Expect = 0.90, Method: Composition-based stats. Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%) Query: 50 PEEI-GWLNGYNETTGERGDFPGTYVEYI 77 PEE GWL G ++TT RG FP +Y + + Sbjct: 38 PEEKDGWLYGEHDTTKARGWFPSSYTKLL 66 >4E68-A nrPDB Length = 596 Score = 32.0 bits (71), Expect = 1.0, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 21/45 (46%) Query: 327 SLQDAEWYWGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLT 371 +L + + G IS+E L GTFL+R + + G T T Sbjct: 452 ALWNEGYIMGFISKERERAILSTKPPGTFLLRFSESSKEGGVTFT 496 >6OJ5-A nrPDB Length = 887 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 30/136 (22%), Positives = 65/136 (47%), Gaps = 15/136 (11%) Query: 433 QDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIK 492 ++ +K+D+ ++ NT + K+ +L E+ +E+ I E IK Sbjct: 10 RETNLKQDDRMQEKEENKNVNTNSENKNATKPQLSEKVLSQKEEV------ITDNQEEIK 63 Query: 493 IFEEQCQTQERYSKEYIEKFK-REGNEKEI-----QRIMHNYDKLKSRISEIIDSRRRLE 546 I +E ++ + SK+ +E K +E ++KE+ Q+ + ++ +S + ++ D + Sbjct: 64 IADEVKKSNKEESKQLLEVLKTKEEHQKEVQYEILQKTIPTFEPKESILKKLEDIK---P 120 Query: 547 EDLKKQAAEYREIDKR 562 E +KKQ +R + R Sbjct: 121 EQVKKQTKLFRIFEPR 136 >3HAJ-A nrPDB Length = 486 Score = 31.6 bits (70), Expect = 1.2, Method: Composition-based stats. Identities = 21/69 (30%), Positives = 31/69 (44%), Gaps = 15/69 (21%) Query: 9 RALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNETTGERGD 68 RALYDY+ + +++ GD LT + +E GW G + G+ G Sbjct: 432 RALYDYEGQEHDELSFKAGDELT--------------KMEDEDEQGWCKGRLD-NGQVGL 476 Query: 69 FPGTYVEYI 77 +P YVE I Sbjct: 477 YPANYVEAI 485 >5AEM-A nrPDB Length = 447 Score = 31.6 bits (70), Expect = 1.3, Method: Composition-based stats. Identities = 38/203 (18%), Positives = 74/203 (36%), Gaps = 29/203 (14%) Query: 447 KKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSK 506 ++L+ YN RE LY +Y R I++ ++ FN ++ Sbjct: 135 QRLYMYNPYDANILRELAILYVDYDRIEDSIEL---YMKVFNANVE-------------- 177 Query: 507 EYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQA---AEYREIDKRM 563 +RE ++ + + D+ + E D + LE+D +Q +++ID + Sbjct: 178 ------RREAILAALENALDSSDEESAAEGEDADEKEPLEQDEDRQMFPDINWKKIDAKY 231 Query: 564 NSIKPDLIQLRKTRDQYLMWLTQK--GVRQ-KKLNEWLGNENTEDQYSLVEDDEDLPHHD 620 I D L + +L + G++ KK W+ ++ + V DD + + Sbjct: 232 KCIPFDWSSLNILAELFLKLAVSEVDGIKTIKKCARWIQRRESQTFWDHVPDDSEFDNRR 291 Query: 621 EKTWNVGSSNRNKAENLLRGKRD 643 K S + E D Sbjct: 292 FKNSTFDSLLAAEKEKSYNIPID 314 >2EQI-A nrPDB Length = 69 Score = 31.2 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 23/75 (30%), Positives = 33/75 (44%), Gaps = 16/75 (21%) Query: 3 AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNET 62 + G +ALYDYK +R ++ LT +G+L+ E GW G + Sbjct: 5 SSGRTVKALYDYKAKRSDE--------LTFCRGALI-------HNVSKEPGGWWKG-DYG 48 Query: 63 TGERGDFPGTYVEYI 77 T + FP YVE I Sbjct: 49 TRIQQYFPSNYVEDI 63 >5XQL-A nrPDB Length = 291 Score = 31.2 bits (69), Expect = 1.8, Method: Composition-based stats. Identities = 15/48 (31%), Positives = 27/48 (56%) Query: 507 EYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAA 554 E I++ KR+G + QR+ H + + + E I +R+RL +L + A Sbjct: 83 EAIDRLKRDGALDDPQRLRHFLQRHQHTLREEISARQRLLAELDRTLA 130 >4CIU-A nrPDB Length = 727 Score = 30.8 bits (68), Expect = 2.1, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 71/166 (42%), Gaps = 31/166 (18%) Query: 430 KYQQDQVVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEY---------TRT-SQEIQM 479 K +Q ++K + EA K+L N + +K R+Y L EE+ T+T E++ Sbjct: 281 KLEQQALMKASD-EASKKRLDMLNEELSDKERQYSELEEEWKAEKASLSGTQTIKAELEQ 339 Query: 480 KRTAIEAFNET-------------IKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMH 526 + AIE I E+Q + + + + + + + EI ++ Sbjct: 340 AKIAIEQARRVGDLARMSELQYGKIPELEKQLEAATQLEGKTMRLLRNKVTDAEIAEVLA 399 Query: 527 NYDKLKSRISEIIDSRR----RLEEDLKKQAAEYRE-IDKRMNSIK 567 + + +S +++S R R+E++L + E +D N+I+ Sbjct: 400 RWTGIP--VSRMMESEREKLLRMEQELHHRVIGQNEAVDAVSNAIR 443 >6MSD-E nrPDB Length = 403 Score = 30.8 bits (68), Expect = 2.2, Method: Composition-based stats. Identities = 13/46 (28%), Positives = 27/46 (58%) Query: 534 RISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTRDQ 579 R+ + D R + +D +K+ E++EID R+ ++ L +L K ++ Sbjct: 11 RLLIMADPRDKALQDYRKKLLEHKEIDGRLKELREQLKELTKQYEK 56 >3NL2-A nrPDB Length = 540 Score = 30.8 bits (68), Expect = 2.3, Method: Composition-based stats. Identities = 23/94 (24%), Positives = 35/94 (37%), Gaps = 1/94 (1%) Query: 53 IGWLNGYNETTGERGDFPGTYVEYIGRKKISPPTPKPRPPR-PLPVAPGSSKTEADVEQQ 111 IGW G+ E E V+YIG + P K P + P+ A +A Sbjct: 111 IGWSVGFPEEVDELSKMGPDMVDYIGVGTLFPTLTKKNPKKAPMGTAGAIRVLDALERNN 170 Query: 112 ALTLPDLAEQFAPPDIAPPLLIKLVEAIEKKGLE 145 A + PD +L + V + K+ L+ Sbjct: 171 AHWCRTVGIGGLHPDNIERVLYQCVSSNGKRSLD 204 >4V3P-LC nrPDB Length = 389 Score = 30.8 bits (68), Expect = 2.4, Method: Composition-based stats. Identities = 15/68 (22%), Positives = 35/68 (51%) Query: 492 KIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKK 551 + ++ C+++++ +Y K+ + +KEIQ + K + + I ++ R + LK+ Sbjct: 117 RFYKNWCKSKKKAFTKYALKYDSDAGKKEIQLQLEKMKKYATIVRVIAHTQIRKMKGLKQ 176 Query: 552 QAAEYREI 559 + A EI Sbjct: 177 KKAHLMEI 184 >1BF5-A nrPDB Length = 575 Score = 30.4 bits (67), Expect = 2.5, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 335 WGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLT 371 G IS+E L+D GTFL+R + + G T T Sbjct: 444 MGFISKERERALLKDQQPGTFLLRFSESSREGAITFT 480 >1YVL-A nrPDB Length = 683 Score = 30.4 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 14/37 (37%), Positives = 19/37 (51%) Query: 335 WGDISREEVNEKLRDTADGTFLVRDASTKMHGDYTLT 371 G IS+E L+D GTFL+R + + G T T Sbjct: 579 MGFISKERERALLKDQQPGTFLLRFSESSREGAITFT 615 >3JA6-G nrPDB Length = 309 Score = 30.4 bits (67), Expect = 2.8, Method: Composition-based stats. Identities = 24/131 (18%), Positives = 52/131 (39%), Gaps = 13/131 (9%) Query: 447 KKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQERYSK 506 KK+ E +++ +R+ E + + ++EI I A E + + + Sbjct: 96 KKVIEVTRMISNSAKDVERVVESFQKGAEEITSFVETINAIAEQTNLLALNAAIEAARAG 155 Query: 507 EYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYR--------- 557 E F + EI+++ + + +++ R + ED K ++E Sbjct: 156 EAGRGFAVVAD--EIRKLAEESQQASENVRRVVNEIRSIAEDAGKVSSEITARVEEGTKL 213 Query: 558 --EIDKRMNSI 566 E D+++NSI Sbjct: 214 ADEADEKLNSI 224 >3S9G-A nrPDB Length = 104 Score = 30.4 bits (67), Expect = 3.0, Method: Composition-based stats. Identities = 18/75 (24%), Positives = 38/75 (50%), Gaps = 7/75 (9%) Query: 499 QTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYRE 558 +T ERY E ++ + Q ++ Y +L+ +S + D RL + K+ A RE Sbjct: 17 ETYERYHTESLQNMSK-------QELIKEYLELEKSLSRMEDENNRLRLESKRLDARVRE 69 Query: 559 IDKRMNSIKPDLIQL 573 ++ ++ ++ + +QL Sbjct: 70 LELELDRLRAENLQL 84 >3B98-A nrPDB Length = 475 Score = 30.4 bits (67), Expect = 3.1, Method: Composition-based stats. Identities = 18/74 (24%), Positives = 37/74 (50%), Gaps = 4/74 (5%) Query: 454 TQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFE----EQCQTQERYSKEYI 509 TQ E+ R +D+L + RT+ + K+ A A + K ++ ++ + Y+ Sbjct: 182 TQIYEEFRRFDKLLPKLARTTVNKEEKQIASAAREKLWKWLTPSGLDRKPREQSWLGSYV 241 Query: 510 EKFKREGNEKEIQR 523 ++ + EG + E+QR Sbjct: 242 KQLQDEGIDAEMQR 255 >3AKZ-B nrPDB Length = 487 Score = 30.1 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 16/77 (20%) Query: 487 FNETIKIFEEQCQTQER--------------YSKEYIEKF-KREGNEKEIQRIMHNYDKL 531 F+ET++I E+ T + Y K+Y+EKF KRE E+ ++ + L Sbjct: 359 FSETLRICREKVNTLSQLYDIMYPFMNDDYEYEKDYVEKFLKREEAERVLEEAKKAFKDL 418 Query: 532 KS-RISEIIDSRRRLEE 547 S + EI + R L E Sbjct: 419 NSWNMEEIEKTLRDLSE 435 >4TKO-B nrPDB Length = 358 Score = 30.1 bits (66), Expect = 3.3, Method: Composition-based stats. Identities = 30/132 (22%), Positives = 58/132 (43%), Gaps = 15/132 (11%) Query: 438 KEDNIEAVGKK---LHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIF 494 K+ +E++ KK L E Q +EK + +E Y Q+ + R E + +K+ Sbjct: 95 KKLKVESLKKKREALREKLLQVEEKIKLVKLDWERYKSLFQKGLIPRRKFEEVDTNLKVL 154 Query: 495 EEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSR---ISEIIDSRRRLEEDLKK 551 + +EY+EK +E N EI+R + ++ I E+ LEE++K Sbjct: 155 --------LHEREYLEKSIQEIN-TEIKRAKKGIENARNEFKTIEELKKELSSLEEEIKS 205 Query: 552 QAAEYREIDKRM 563 + ++++ Sbjct: 206 LKERIKTAEQKI 217 >3AL0-C nrPDB Length = 592 Score = 30.1 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 23/77 (29%), Positives = 36/77 (46%), Gaps = 16/77 (20%) Query: 487 FNETIKIFEEQCQTQER--------------YSKEYIEKF-KREGNEKEIQRIMHNYDKL 531 F+ET++I E+ T + Y K+Y+EKF KRE E+ ++ + L Sbjct: 464 FSETLRICREKVNTLSQLYDIMYPFMNDDYEYEKDYVEKFLKREEAERVLEEAKKAFKDL 523 Query: 532 KS-RISEIIDSRRRLEE 547 S + EI + R L E Sbjct: 524 NSWNMEEIEKTLRDLSE 540 >3W4R-A nrPDB Length = 554 Score = 30.1 bits (66), Expect = 3.8, Method: Composition-based stats. Identities = 15/34 (44%), Positives = 19/34 (55%), Gaps = 1/34 (2%) Query: 83 SPPTPKPRPPRPLPVAPGSSKTEADVEQQALTLP 116 S P PKP P P AP +S TE + +Q + LP Sbjct: 455 SRPEPKPTTSLPTP-APTASTTEEEAQQPEVELP 487 >3JAX-A nrPDB Length = 974 Score = 29.7 bits (65), Expect = 4.4, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 40/84 (47%) Query: 518 EKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPDLIQLRKTR 577 EKE+ + + +LK + + R+ LEE + E ++ ++ + + +L + Sbjct: 857 EKEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERC 916 Query: 578 DQYLMWLTQKGVRQKKLNEWLGNE 601 DQ + Q + K++NE L +E Sbjct: 917 DQLIKNKIQLEAKVKEMNERLEDE 940 >6FSW-A nrPDB Length = 236 Score = 29.7 bits (65), Expect = 4.5, Method: Composition-based stats. Identities = 24/102 (23%), Positives = 37/102 (36%), Gaps = 12/102 (11%) Query: 74 VEYIGRKKISPPTPKPRPPRPLPVAPGSSKTEADV-EQQALTLPDLAEQFAPPDIAPPLL 132 + +I R I P T P PP + A +K D+ + + D+ + P I P Sbjct: 106 INFISRNTIDPRTNAPHPPSRIERALEEAKVHIDIFKSVEAQVKDIVKALKP--ILPLKF 163 Query: 133 IKLVEAI----EKKGLECSTLYRTQSSSNLAELRQLLDCDTP 170 ++ AI E G S LY + R+ D Sbjct: 164 EEMEIAIKIPPEHTGRAISALYNFGGVT-----REEWQRDGS 200 >6FYX-o nrPDB Length = 964 Score = 29.7 bits (65), Expect = 4.6, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 51/104 (49%), Gaps = 6/104 (5%) Query: 467 YEEYTRTSQEIQMKRTA--IEAFNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRI 524 Y E R ++E +K+ +E ++ + ++ Q Q++ E+ + E QRI Sbjct: 575 YMEKVRIARETLIKKNKDDLEKISKIVDERVKRSQEQKQKHMEHAALHAEQDAEVRQQRI 634 Query: 525 MHNYDKLKSRISEIIDSRRRLEEDLKKQ--AAEYREIDKRMNSI 566 + +++++ E ++ RRL E K++ A + REI K + + Sbjct: 635 LEEKAAIEAKLEE--EAHRRLIEKKKREFEAIKEREITKMITEV 676 >2DLM-A nrPDB Length = 68 Score = 29.7 bits (65), Expect = 5.0, Method: Composition-based stats. Identities = 19/75 (25%), Positives = 32/75 (42%), Gaps = 17/75 (22%) Query: 3 AEGYQYRALYDYKKEREEDIDLHLGDILTVNKGSLVALGFSDGQEARPEEIGWLNGYNET 62 + G R +D++ + +++ L GDI+ ++K + WL G E Sbjct: 5 SSGKAARLKFDFQAQSPKELTLQKGDIVYIHK---------------EVDKNWLEG--EH 47 Query: 63 TGERGDFPGTYVEYI 77 G G FP YVE + Sbjct: 48 HGRLGIFPANYVEVL 62 >1XDV-A nrPDB Length = 847 Score = 29.7 bits (65), Expect = 5.2, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 517 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEED-LKKQAAEYREID 560 N + R+ H ++++ SR +I++ L ED KK A+ R I+ Sbjct: 682 NSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSIN 726 >5J1I-A nrPDB Length = 373 Score = 29.3 bits (64), Expect = 5.5, Method: Composition-based stats. Identities = 27/116 (23%), Positives = 51/116 (43%), Gaps = 15/116 (12%) Query: 458 EKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFEEQCQTQE----------RYSKE 507 + + E R +EE + +Q + +EA ++K Q + Q+ R ++E Sbjct: 127 QGAEEVLRAHEEQLKEAQAVPATLPELEATKASLKKLRAQAEAQQPTFDALRDELRGAQE 186 Query: 508 YIEKFKREGNEK--EIQRIMHNYDKLKSRISEII---DSRRRLEEDLKKQAAEYRE 558 E+ ++ E+ E++R +L R ++ D R+R E L +Q YRE Sbjct: 187 VGERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRE 242 >5OQL-o nrPDB Length = 239 Score = 29.3 bits (64), Expect = 6.6, Method: Composition-based stats. Identities = 21/61 (34%), Positives = 30/61 (49%), Gaps = 9/61 (14%) Query: 522 QRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREI-DKRMNSIKPDLIQLRKTRDQY 580 QR+ H + I +RR +E +K++AAEY +I KR+ K LRK R Sbjct: 185 QRLQHKRHR--------IALKRRQQEKVKEEAAEYAQILAKRVAEAKAQKADLRKRRASS 236 Query: 581 L 581 L Sbjct: 237 L 237 >5OVF-A nrPDB Length = 490 Score = 29.3 bits (64), Expect = 7.0, Method: Composition-based stats. Identities = 14/45 (31%), Positives = 25/45 (55%), Gaps = 1/45 (2%) Query: 517 NEKEIQRIMHNYDKLKSRISEIIDSRRRLEED-LKKQAAEYREID 560 N + R+ H ++++ SR +I++ L ED KK A+ R I+ Sbjct: 320 NSSPVYRLDHTFEQIPSRQKKILEEAHELSEDHYKKYLAKLRSIN 364 >1XAD-A nrPDB Length = 345 Score = 28.9 bits (63), Expect = 7.6, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 487 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLE 546 F E + E + ERYSK +E+ R E +R H K+ + E+ + R+ Sbjct: 140 FGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEVGEFWRKTV 199 Query: 547 EDLKKQ----AAEYREID 560 E++ + A E++ +D Sbjct: 200 EEVGRGYPDVALEHQYVD 217 >1IDM-A nrPDB Length = 343 Score = 28.9 bits (63), Expect = 7.6, Method: Composition-based stats. Identities = 20/78 (25%), Positives = 36/78 (46%), Gaps = 4/78 (5%) Query: 487 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLE 546 F E + E + ERYSK +E+ R E +R H K+ + E+ + R+ Sbjct: 138 FGEPRGMSEAEAWNTERYSKPEVERVARVAFEAARKRRKHVVSVDKANVLEVGEFWRKTV 197 Query: 547 EDLKKQ----AAEYREID 560 E++ + A E++ +D Sbjct: 198 EEVGRGYPDVALEHQYVD 215 >4KMA-A nrPDB Length = 498 Score = 28.9 bits (63), Expect = 8.0, Method: Composition-based stats. Identities = 16/84 (19%), Positives = 40/84 (47%), Gaps = 2/84 (2%) Query: 487 FNETIKIFEEQCQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLE 546 F + + +F+++ + R++ + F R+ + ++ N D+ S ++ L+ Sbjct: 223 FCQIVGVFDDELEQASRWNGRGVLNFLRQDMQTGGDWLVTNMDRQMSVFELFPETLLNLQ 282 Query: 547 EDLKKQAAEYREI--DKRMNSIKP 568 +DL+KQ ++ + D +KP Sbjct: 283 DDLEKQGSDLAGVNADFTFRELKP 306 >2P22-C nrPDB Length = 192 Score = 28.9 bits (63), Expect = 8.1, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 66/165 (40%), Gaps = 41/165 (24%) Query: 436 VVKEDNIEAVGKKLHEYNTQFQEKSREYDRLYEEYTRTSQEIQMKRTAIEAFNETIKIFE 495 V K + + K+H + QF++ ++ L+E ++ ++A E +I E Sbjct: 58 VTKFNPLTDFAGKIHAFRDQFKQLEENFEDLHE-----------QKDKVQALLENARILE 106 Query: 496 EQ-CQTQERYSKEYIEKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAA 554 + + + Y E+ +K+ I +++LE++ KK Sbjct: 107 SKYVASWQDYHSEFSKKYGD------------------------IALKKKLEQNTKKLDE 142 Query: 555 EYREIDKRMNSIKP--DLIQLRKTRDQYLMWLTQKGVRQKKLNEW 597 E +++ SI DL Q K YL TQ +R++KL W Sbjct: 143 ESSQLETTTRSIDSADDLDQFIK---NYLDIRTQYHLRREKLATW 184 >2PZ9-A nrPDB Length = 226 Score = 28.9 bits (63), Expect = 8.5, Method: Composition-based stats. Identities = 25/123 (20%), Positives = 40/123 (32%), Gaps = 17/123 (13%) Query: 82 ISPPTPKPRPPRP--LPVAPGSSKTEADVEQQALTLPDLAEQFAPPDIAPPLLIKLV--- 136 ++ P P PR P P P AP S D +Q + + E+FA IA + ++ Sbjct: 2 VAYPGPMPRSPSPGQTPDAPTSGGGSTDSTRQRI-VAAAKEEFARHGIAGARVDRIAKQA 60 Query: 137 ----EAIEKKGLECSTLYRTQSSSNLAELRQLLDCDTPSVDLEMIDVHVLADAFKRYLLD 192 E + LY + L + D D+ A + Sbjct: 61 RTSKERVYAYFRSKEALYAHVAERETTALIEATQLDPA-------DLPGYAGILFDHFAA 113 Query: 193 LPN 195 P+ Sbjct: 114 RPD 116 >6HIY-Cj nrPDB Length = 257 Score = 28.9 bits (63), Expect = 8.6, Method: Composition-based stats. Identities = 33/131 (25%), Positives = 54/131 (41%), Gaps = 21/131 (16%) Query: 2 SAEGYQYRALYDYKKEREEDIDLHLGDILTVNKG-SLVALGFS-DGQEARPEEIGWLNGY 59 S Y R Y+KE +E T +K +L A+ F DG + G++ + Sbjct: 105 SQATYNGRGQRFYRKEWQEG---------TYDKYVTLSAIDFDRDGNKG--TAYGYITFH 153 Query: 60 NETTG-----ERGDFPGTYVEYIGRKKISPPTPKPRPPR---PLPVAPGSSKTEADVEQQ 111 ETT + D PG Y++++ + + P PP +PV P S + +A Sbjct: 154 GETTTRPVQVDFADVPGWYMDFVEERAVPFTGIVPPPPSIGTDVPVDPHSYRLKAYPYYD 213 Query: 112 ALTLPDLAEQF 122 A P+ E+ Sbjct: 214 APNPPEFVERL 224 >1PWU-A nrPDB Length = 776 Score = 28.5 bits (62), Expect = 9.8, Method: Composition-based stats. Identities = 19/66 (28%), Positives = 33/66 (50%), Gaps = 5/66 (7%) Query: 510 EKFKREGNEKEIQRIMHNYDKLKSRISEIIDSRRRLEEDLKKQAAEYREIDKRMNSIKPD 569 EK K E K+ +R + LK + I+ + EE +KK+AAE K + + D Sbjct: 15 EKNKDENKRKDEERNKTQEEHLKEIMKHIVKIEVKGEEAVKKEAAE-----KLLEKVPSD 69 Query: 570 LIQLRK 575 ++++ K Sbjct: 70 VLEMYK 75 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.132 0.363 Lambda K H 0.267 0.0391 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 28,427,876 Number of Sequences: 36641 Number of extensions: 1212324 Number of successful extensions: 4877 Number of sequences better than 10.0: 193 Number of HSP's better than 10.0 without gapping: 158 Number of HSP's successfully gapped in prelim test: 175 Number of HSP's that attempted gapping in prelim test: 4205 Number of HSP's gapped (non-prelim): 573 length of query: 724 length of database: 10,336,785 effective HSP length: 104 effective length of query: 620 effective length of database: 6,526,121 effective search space: 4046195020 effective search space used: 4046195020 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.5 bits) S2: 63 (28.9 bits)