BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P27796 (417 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 1PXT-A nrPDB 794 0.0 2IIK-A nrPDB 373 e-104 2C7Y-A nrPDB 338 3e-93 2WUA-A nrPDB 338 4e-93 4DD5-A nrPDB 249 2e-66 3GOA-A nrPDB 239 2e-63 3SS6-A nrPDB 236 1e-62 4E1L-A nrPDB 231 3e-61 4N44-A nrPDB 229 1e-60 1ULQ-A nrPDB 226 2e-59 1WL4-A nrPDB 224 7e-59 1NL7-A nrPDB 221 4e-58 4NZS-A nrPDB 221 5e-58 4O9A-A nrPDB 215 2e-56 1WDK-C nrPDB 214 6e-56 4WYS-A nrPDB 212 2e-55 6BJA-A nrPDB 210 9e-55 4C2K-A nrPDB 209 2e-54 5LP7-H nrPDB 208 3e-54 4B3J-C nrPDB 201 5e-52 2IBU-A nrPDB 201 5e-52 5CBQ-A nrPDB 200 8e-52 6ARG-A nrPDB 197 1e-50 3SVK-A nrPDB 196 2e-50 5XYJ-B nrPDB 192 3e-49 6BN2-A nrPDB 192 3e-49 6BJB-A nrPDB 187 9e-48 4UBW-A nrPDB 169 3e-42 5ZQZ-B nrPDB 159 2e-39 5LNQ-A nrPDB 60 1e-09 6ESQ-A nrPDB 50 1e-06 4BI9-A nrPDB 49 3e-06 6HRV-A nrPDB 47 2e-05 4YZO-A nrPDB 33 0.18 1XKH-A nrPDB 32 0.47 2W78-A nrPDB 32 0.58 1UXV-A nrPDB 30 1.8 3E60-A nrPDB 30 2.0 2HGS-A nrPDB 30 2.1 5M3K-C nrPDB 29 3.5 5LFK-A nrPDB 28 5.9 4JRH-A nrPDB 28 7.7 >1PXT-A nrPDB Length = 390 Score = 794 bits (2050), Expect = 0.0, Method: Compositional matrix adjust. Identities = 390/390 (100%), Positives = 390/390 (100%) Query: 28 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE 87 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE Sbjct: 1 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE 60 Query: 88 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG 147 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG Sbjct: 61 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG 120 Query: 148 LALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF 207 LALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF Sbjct: 121 LALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF 180 Query: 208 AANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGT 267 AANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGT Sbjct: 181 AANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGT 240 Query: 268 TTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVL 327 TTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVL Sbjct: 241 TTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVL 300 Query: 328 EATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVAT 387 EATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVAT Sbjct: 301 EATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVAT 360 Query: 388 ILRELKKDQIGVVSMCIGTGMGAAAIFIKE 417 ILRELKKDQIGVVSMCIGTGMGAAAIFIKE Sbjct: 361 ILRELKKDQIGVVSMCIGTGMGAAAIFIKE 390 >2IIK-A nrPDB Length = 418 Score = 373 bits (958), Expect = e-104, Method: Compositional matrix adjust. Identities = 211/395 (53%), Positives = 262/395 (66%), Gaps = 27/395 (6%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNL----IEEVAC 90 DVV+V R+AI + +G FKD D LL + + D+NL + ++ Sbjct: 31 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVL--------KDVNLRPEQLGDICV 82 Query: 91 GNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 GNVL GAGA R A S IP + P +NRQCSSGL AV IA I+ G DIG+A Sbjct: 83 GNVLQPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMAC 142 Query: 151 GVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAAN 210 GVESM+ + NP G I+S ++K + A+ CLIPMGIT+ENVA F ISR+ QD FA Sbjct: 143 GVESMSLADRG-NP-GNITSRLMEKEK-ARDCLIPMGITSENVAERFGISREKQDTFALA 199 Query: 211 SYQKAYKAKNEGLFEDEILPI-------KLPDGSICQS-DEGPRPNVTAESLSSIRPAFI 262 S QKA +A+++G F+ EI+P+ K SI + DEG RP+ T E L+ ++PAF Sbjct: 200 SQQKAARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFK 259 Query: 263 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 322 KD G+TTAGN+SQVSDG A +LLARRS A +L LP+LG + VGVPP+IMG+GPAYA Sbjct: 260 KD-GSTTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYA 318 Query: 323 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 IP L+ GL V D+DIFEINEAFA+QA YC+ KL + KVNP GGA+ALGHPLGCTGA Sbjct: 319 IPVALQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGA 378 Query: 383 RQVATILRELK---KDQIGVVSMCIGTGMGAAAIF 414 RQV T+L ELK K GVVSMCIGTGMGAAA+F Sbjct: 379 RQVITLLNELKRRGKRAYGVVSMCIGTGMGAAAVF 413 >2C7Y-A nrPDB Length = 404 Score = 338 bits (867), Expect = 3e-93, Method: Compositional matrix adjust. Identities = 196/399 (49%), Positives = 256/399 (64%), Gaps = 30/399 (7%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +DVVIVAA+R+ + K +G FKD D LL L I E + + + ++ G V Sbjct: 13 DDVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALI----EKTNLNPSEVGDIVVGTV 68 Query: 94 LNVGAG-ATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 L G+ A+E R A +G P + +NRQCSSGL AV D+A IK G DIG+ G+ Sbjct: 69 LAPGSQRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAAAIKAGFYDIGIGAGL 128 Query: 153 ESMTNN----YKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFA 208 ESMT N +VNP ++K +A+ CL+PMG+T+ENVA F +SR++QD+ A Sbjct: 129 ESMTTNPMAWEGSVNP-------AVKKFAQAQNCLLPMGVTSENVAQRFGVSRQEQDQAA 181 Query: 209 ANSYQKAYKAKNEGLFEDEILPIK--LPDGSI-------CQSDEGPRPNVTAESLSSIRP 259 +S++KA A G F+DEI+P+K L D D+G RP T SL ++P Sbjct: 182 VDSHRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPTTTLASLGKLKP 241 Query: 260 AFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 F KD GTTTAGN+SQVSDG VLL +RSVA Q LPVLG + F VGV P IMG+GP Sbjct: 242 VFKKD-GTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAVGVDPAIMGIGP 300 Query: 320 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGC 379 A AIP ++A GL++ DID+FEINEAFA+Q +YC +KLG+D K+N GGA+A+GHPLG Sbjct: 301 AVAIPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNGGAMAIGHPLGA 360 Query: 380 TGARQVATILRELKKD----QIGVVSMCIGTGMGAAAIF 414 TGAR VAT+L E+K+ + GVVSMCIGTGMGAAA+F Sbjct: 361 TGARCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVF 399 >2WUA-A nrPDB Length = 440 Score = 338 bits (866), Expect = 4e-93, Method: Compositional matrix adjust. Identities = 195/417 (46%), Positives = 257/417 (61%), Gaps = 33/417 (7%) Query: 16 AMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFP 75 A G + ++NS+ +DVVIVAA RS + K +G KD D +L L I Sbjct: 18 AAGDSAAYQRNSVFG---DDVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALI---- 70 Query: 76 EPLRADLNLIEEVACGNVLNVGAG-ATEHRAACLASGIPYSTPFVALNRQCSSGLTAVND 134 E + + ++ G+VL G+ A+E R A +G P + P +NRQCSSGL AV D Sbjct: 71 EKTNINPAEVGDIVVGSVLGAGSQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVAD 130 Query: 135 IANKIKVGQIDIGLALGVESMTNN----YKNVNPLGMISSEELQKNREAKKCLIPMGITN 190 +A IK G DIG+ G+ESMT N +VNP +++ +A+ CL+PMGIT+ Sbjct: 131 VAAAIKAGFYDIGIGAGLESMTANPMAWEGSVNP-------KVKTMAQAQDCLLPMGITS 183 Query: 191 ENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGP----- 245 ENVA F I+R++QD+ A S++K A G F+DEI+PIK DE P Sbjct: 184 ENVAQKFSITRQEQDQAAVGSHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISV 243 Query: 246 ----RPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGR 301 RP + L+ ++P F KD G+TTAG +SQVSDG VLL +RS+A Q LP+LG Sbjct: 244 DDGIRPGTSLADLAKLKPVFRKD-GSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGV 302 Query: 302 YIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDL 361 + F VGVPP IMG+GPA AIP ++A GLQ+ DID+FEINEAFA+Q +YC KL ID Sbjct: 303 FRTFAAVGVPPSIMGIGPAVAIPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDP 362 Query: 362 NKVNPRGGAIALGHPLGCTGARQVATILRELKKD----QIGVVSMCIGTGMGAAAIF 414 K+N GGA+A+GHPLG TGAR VAT+L E+K+ + GVVSMCIGTGMGAAA+F Sbjct: 363 QKINVNGGAMAIGHPLGATGARCVATLLHEMKRRGRDCRFGVVSMCIGTGMGAAAVF 419 >4DD5-A nrPDB Length = 396 Score = 249 bits (635), Expect = 2e-66, Method: Compositional matrix adjust. Identities = 157/399 (39%), Positives = 228/399 (57%), Gaps = 33/399 (8%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADL--NLIEEVACGN 92 +VVI +A R+A+G F GAFK V+ L E I R A++ ++I+E G Sbjct: 8 EVVIASAARTAVGS-FGGAFKSVSAVELGVTAAKEAIKR------ANITPDMIDESLLGG 60 Query: 93 VLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 VL G G R L +GIP P + +N C SGL +V+ + I +G DI L G Sbjct: 61 VLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGGA 120 Query: 153 ESMTNNYKNVNPLGMISSEELQKNREAK--KCLIP-----------MGITNENVAANFKI 199 E+M+ ++P + S+ + +A +I MGIT EN+A + I Sbjct: 121 ENMS-----MSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNI 175 Query: 200 SRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKL---PDGSICQSDEGPRPNVTAESLSS 256 +R++QDE A S KA KA+ EG F++EI+P+ + ++ DE +P T E L+ Sbjct: 176 TREEQDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGTTMEKLAK 235 Query: 257 IRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMG 316 +RPAF KD GT TAGNAS ++DG A +++ + A +L + L + + T GV P+IMG Sbjct: 236 LRPAFKKD-GTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMG 294 Query: 317 VGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHP 376 GP A K LEA + ++DID+ E NEAFAAQ++ I L ID+NKVN GGAIA+GHP Sbjct: 295 YGPVPATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHP 354 Query: 377 LGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAI 413 +GC+GAR + T+L E+K+ + G+ ++CIG GMG I Sbjct: 355 IGCSGARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLI 393 >3GOA-A nrPDB Length = 387 Score = 239 bits (610), Expect = 2e-63, Method: Compositional matrix adjust. Identities = 158/391 (40%), Positives = 206/391 (52%), Gaps = 18/391 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 E VVIV A R+ +G+ GAF++V + L + + + R P A L+ I Sbjct: 2 EQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAATLDDIYWGCVQQT 61 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G R A L + IP+S P V +NR C S + A++D A I G + L GVE Sbjct: 62 LEQGFNIA--RNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGVE 119 Query: 154 SMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQ 213 M + P+ +R K MG+T E ++ ISR+ QD+FAA S+ Sbjct: 120 HMGHV-----PMSHGVDFHPGLSRNVAKAAGMMGLTAEMLSRLHGISREMQDQFAARSHA 174 Query: 214 KAYKAKNEGLFEDEILPI--KLPDGSICQ--SDEGPRPNVTAESLSSIRPAFIKDRGTTT 269 +A+ A G F+ EI+P DG + Q DE RP T E+LS++RPAF GT T Sbjct: 175 RAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFDPVSGTVT 234 Query: 270 AGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLEA 329 AG +S +SDG A +L+ S A +L L R VG P IMG GP A L+ Sbjct: 235 AGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKLALKK 294 Query: 330 TGLQVQDIDIFEINEAFAAQALYCIHKLG----IDLNKVNPRGGAIALGHPLGCTGARQV 385 GL DID+FE+NEAFAAQ L CI LG ID K+N GGAIALGHPLGC+GAR Sbjct: 295 AGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQID-EKINLNGGAIALGHPLGCSGARIS 353 Query: 386 ATI--LRELKKDQIGVVSMCIGTGMGAAAIF 414 T+ L E K Q G+ +MCIG G G A +F Sbjct: 354 TTLINLMERKDAQFGLATMCIGLGQGIATVF 384 >3SS6-A nrPDB Length = 394 Score = 236 bits (603), Expect = 1e-62, Method: Compositional matrix adjust. Identities = 153/401 (38%), Positives = 224/401 (55%), Gaps = 31/401 (7%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRF-PEPLRADLNLIEEVACGN 92 +VVI AA RS IG F GA K+V L L E + R EP D EV G+ Sbjct: 5 HNVVITAAVRSPIGT-FGGALKNVTPVELAVPVLQEAVKRGGVEPHEVD-----EVILGH 58 Query: 93 VLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 + A R A LA+G P + + RQCSSG+ A+ A +I++G ++ +A GV Sbjct: 59 CIQRTDEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGV 118 Query: 153 ESMTNNYKNVNPLGMISSEELQK--NREAKKCL----------IPMGITNENVAANFKIS 200 E+M+++ P + Q+ + E + + I MG T EN+ ++I+ Sbjct: 119 EAMSSS-----PYALKQHRWGQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLVEQYEIT 173 Query: 201 RKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSI 257 R++QDE A S+ A KA G F+D+I+PI + + + DE PR ++TAE L+ + Sbjct: 174 REEQDEVALRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGL 233 Query: 258 RPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGV 317 +PAF KD G+ TAGNAS ++DG A ++L A + L L R + + GV P+IMG+ Sbjct: 234 KPAFRKD-GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGI 292 Query: 318 GPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPL 377 GPA AI K LE ++D D+ EINEAFAAQ L +L +D KVN G + LGHP+ Sbjct: 293 GPAPAIRKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPI 352 Query: 378 GCTGARQVATILRELKKDQI--GVVSMCIGTGMGAAAIFIK 416 GCTGAR +++ ELK+ + G+ S+C+G G+G A+FI+ Sbjct: 353 GCTGARITVSLIHELKRRGLEKGIASLCVGGGIG-VALFIE 392 >4E1L-A nrPDB Length = 395 Score = 231 bits (590), Expect = 3e-61, Method: Compositional matrix adjust. Identities = 153/395 (38%), Positives = 223/395 (56%), Gaps = 22/395 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +DVVIV+A R+ IG F G FK+ + L + E I R + +L+ I+EV GNV Sbjct: 5 KDVVIVSAVRTPIGS-FGGVFKNTSAVQLGTIAVKEAISR----VGLNLSEIDEVIIGNV 59 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R + +GIP S P +N+ C SGL +V A I G+ D+ +A G E Sbjct: 60 LQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTE 119 Query: 154 SMTNNYKNVNPLGMISSEE---LQKNREAKKCLIP------MGITNENVAANFKISRKDQ 204 +M+ + P S+ + LI MGIT EN+A F+ +R+ Q Sbjct: 120 NMSQ-APYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQ 178 Query: 205 DEFAANSYQKAYKAKNEGLFEDEILPIK--LPDGSI--CQSDEGPRPNVTAESLSSIRPA 260 D+ A S KA A F++EI+P+ + G I DE P+ +T E LS ++PA Sbjct: 179 DKLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPA 238 Query: 261 FIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPA 320 F KD GT TAGNAS ++DG A ++L + A++L + L + + + GV PE+MG GP Sbjct: 239 FKKD-GTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPI 297 Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCT 380 A K L+ GL + DID+ E NEAFAAQAL ++L ID +K+N GGAIALGHP+G + Sbjct: 298 PATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGAS 357 Query: 381 GARQVATILRELKKDQI--GVVSMCIGTGMGAAAI 413 GAR + T++ E++K ++ G+ ++CIG G G + + Sbjct: 358 GARILVTLIYEMQKRKVETGLATLCIGGGQGISMV 392 >4N44-A nrPDB Length = 400 Score = 229 bits (585), Expect = 1e-60, Method: Compositional matrix adjust. Identities = 155/399 (38%), Positives = 221/399 (55%), Gaps = 25/399 (6%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFI---GRFPEPLRADLNLIEEVAC 90 ++VVI +A R+AIG + + KDV L + E + G PE D+N EV Sbjct: 2 KEVVIASAVRTAIGS-YGKSLKDVPAVDLGATAIKEAVKKAGIKPE----DVN---EVIL 53 Query: 91 GNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 GNVL G G R A +G+P P + +N+ C SGL V+ A IK G D+ +A Sbjct: 54 GNVLQAGLGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAG 113 Query: 151 GVESMT------NNYKNVNPLG--MISSEELQKNREAKKCLIPMGITNENVAANFKISRK 202 G+E+M+ NN + +G E + MGIT EN+A + ISR+ Sbjct: 114 GMENMSRAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISRE 173 Query: 203 DQDEFAANSYQKAYKAKNEGLFEDEILP--IKLPDG-SICQSDEGPRPNVTAESLSSIRP 259 +QDEFA S +KA +A G F+DEI+P IK G ++ +DE PR T E L+ ++P Sbjct: 174 EQDEFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKP 233 Query: 260 AFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 AF KD GT TAGNAS ++D A +++ A +L + L + + + + GV P IMG GP Sbjct: 234 AFKKD-GTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGP 292 Query: 320 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGC 379 YA +E G V ++D+ E NEAFAAQ+L L D+NKVN GGAIALGHP+G Sbjct: 293 FYATKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGA 352 Query: 380 TGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 +GAR + T++ ++K + G+ ++CIG G G A + K Sbjct: 353 SGARILVTLVHAMQKRDAKKGLATLCIGGGQGTAILLEK 391 >1ULQ-A nrPDB Length = 401 Score = 226 bits (576), Expect = 2e-59, Method: Compositional matrix adjust. Identities = 150/400 (37%), Positives = 208/400 (52%), Gaps = 27/400 (6%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94 + IV A R+ IGK GA V D LL + L+ + R P +E+V G Sbjct: 3 EAWIVEAVRTPIGK-HGGALASVRPDDLLAHALSVLVDRSGVPKEE----VEDVYAGCAN 57 Query: 95 NVGAGATE-HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 G R A L +G P +NR C SGL AV A I G+ + + GVE Sbjct: 58 QAGEDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVE 117 Query: 154 SMTNNYKNVN------PLG-------MISSEELQKNREAKKCLIPMGITNENVAANFKIS 200 SM+ V P G + + +A MG T EN+A + I Sbjct: 118 SMSRAPYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIR 177 Query: 201 RKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSI 257 R++QD FA S+QKA +A EG F+DE++P+ + G + + DEGPR + + E L+++ Sbjct: 178 REEQDRFALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDTSLEKLAAL 237 Query: 258 RPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGV 317 RP F ++ GT TAGN+S ++DG A VLL A L L R GVPP IMG+ Sbjct: 238 RPVF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGI 296 Query: 318 GPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDL--NKVNPRGGAIALGH 375 GP A K LE GL D+ + E+NEAFAAQAL + + + + ++NP GGAIALGH Sbjct: 297 GPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGH 356 Query: 376 PLGCTGARQVATILREL--KKDQIGVVSMCIGTGMGAAAI 413 PLG +GAR + T++ E+ +K Q G+ +MCIG G G A + Sbjct: 357 PLGASGARILTTLVHEMRRRKVQFGLATMCIGVGQGIAVV 396 >1WL4-A nrPDB Length = 397 Score = 224 bits (570), Expect = 7e-59, Method: Compositional matrix adjust. Identities = 151/402 (37%), Positives = 216/402 (53%), Gaps = 28/402 (6%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRF---PEPLRADLNLIEEVAC 90 + VVIV+A R+ IG F GA V L + E + R PE + EV Sbjct: 6 DPVVIVSAARTIIGS-FNGALAAVPVQDLGSTVIKEVLKRATVAPED-------VSEVIF 57 Query: 91 GNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 G+VL G G R A + +GIPYS P + C SGL AV I +G I +A Sbjct: 58 GHVLAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAG 117 Query: 151 GVESMTNNYK--------NVNPLGMISSEELQKNREA-KKCLIPMGITNENVAANFKISR 201 G+E+M+ + + + S +A C MGIT ENVA +++SR Sbjct: 118 GMENMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNC--HMGITAENVAKKWQVSR 175 Query: 202 KDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP--DGSI-CQSDEGPRPNVTAESLSSIR 258 +DQD+ A S + A+ G F+ EI+P+ + G I ++DE PR E++S ++ Sbjct: 176 EDQDKVAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLK 235 Query: 259 PAFIKD-RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGV 317 P F+ D GT T NAS ++DG A V+L ++S A++ L L R + + VGV P IMG+ Sbjct: 236 PYFLTDGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGI 295 Query: 318 GPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPL 377 GP AI + + G ++D+DIFEINEAFAA + + +LG++ KVN GGAIALGHPL Sbjct: 296 GPIPAIKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPL 355 Query: 378 GCTGARQVATILRELKK--DQIGVVSMCIGTGMGAAAIFIKE 417 G +G R + T+L L++ GV ++CIG GMG A +E Sbjct: 356 GASGCRILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397 >1NL7-A nrPDB Length = 392 Score = 221 bits (563), Expect = 4e-58, Method: Compositional matrix adjust. Identities = 148/388 (38%), Positives = 212/388 (54%), Gaps = 18/388 (4%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 +VI +A R+A+G F GAF + L ++ + E + EV G VL Sbjct: 5 IVIASAARTAVGS-FNGAFANTPAHELGATVISAVL----ERAGVAAGEVNEVILGQVLP 59 Query: 96 VGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESM 155 G G R A + +G+P +N+ C SGL AV +I G I +A G+ESM Sbjct: 60 AGEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESM 119 Query: 156 TNNYKNVNPLGMISSEELQK-NREAKKCLIP------MGITNENVAANFKISRKDQDEFA 208 + + G + + + + K L MG T ENVA +++SR +QD FA Sbjct: 120 SMAPHCAHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFA 179 Query: 209 ANSYQKAYKAKNEGLFEDEILP--IKLPDGSIC-QSDEGPRPNVTAESLSSIRPAFIKDR 265 S KA A+ +G F+DEI+P +K G I +DE R T +S++ +RPAF K+ Sbjct: 180 VASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKE- 238 Query: 266 GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPK 325 GT TAGNAS ++DG A LL + A++ + LGR + + TVGV P++MG GP A K Sbjct: 239 GTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRK 298 Query: 326 VLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQV 385 LE G ++ D+D+ E NEAFAAQA LG D + VN GGAIA+GHP+G +GAR + Sbjct: 299 ALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARIL 358 Query: 386 ATILRELKKD--QIGVVSMCIGTGMGAA 411 T+L E+K+ + G+ ++CIG GMG A Sbjct: 359 NTLLFEMKRRGARKGLATLCIGGGMGVA 386 >4NZS-A nrPDB Length = 399 Score = 221 bits (563), Expect = 5e-58, Method: Compositional matrix adjust. Identities = 147/401 (36%), Positives = 209/401 (52%), Gaps = 32/401 (7%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +VV+V+ R+AIG F G+ KDV L + E + R + + + V GNV Sbjct: 8 REVVVVSGVRTAIGT-FGGSLKDVAPAELGALVVREALAR----AQVSGDDVGHVVFGNV 62 Query: 94 LNVGAGATE------HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG 147 + TE R A + G+ + P + +NR C SGL A+ A I +G D+ Sbjct: 63 IQ-----TEPRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVA 117 Query: 148 LALGVESMTNN---------YKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFK 198 + G ESM+ + G++ + + I MG+T ENVA + Sbjct: 118 IGGGAESMSRAPYLAPAARWGARMGDAGLV--DMMLGALHDPFHRIHMGVTAENVAKEYD 175 Query: 199 ISRKDQDEFAANSYQKAYKAKNEGLFEDEILPI--KLPDGSIC-QSDEGPRPNVTAESLS 255 ISR QDE A S+++A A G F+D+I+P+ K G + +DE R + T + ++ Sbjct: 176 ISRAQQDEAALESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMT 235 Query: 256 SIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIM 315 +RP F+K+ GT TAGNAS ++D A V++ R+ A + L L R + + GV P+ M Sbjct: 236 KLRPVFVKENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAM 295 Query: 316 GVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGH 375 G+GP A LE GLQV D+D+ E NEAFAAQA LG+D KVNP G I+LGH Sbjct: 296 GIGPVPATKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGH 355 Query: 376 PLGCTGARQVATILRELKKDQ--IGVVSMCIGTGMGAAAIF 414 P+G TGA L EL + Q +V+MCIG G G AAIF Sbjct: 356 PIGATGALITVKALHELNRVQGRYALVTMCIGGGQGIAAIF 396 >4O9A-A nrPDB Length = 398 Score = 215 bits (548), Expect = 2e-56, Method: Compositional matrix adjust. Identities = 152/399 (38%), Positives = 216/399 (54%), Gaps = 36/399 (9%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLN---EFIGRFPEPLRADLNLIEEVACG 91 DVVIV+A R+A+GK F G+ + L + E G PE + EV G Sbjct: 8 DVVIVSAARTAVGK-FGGSLAKIPAPELGAVVIKAALERAGVKPEQ-------VSEVIMG 59 Query: 92 NVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALG 151 VL G+G R A + +G+P P + +N+ SGL AV AN I G +I +A G Sbjct: 60 QVLTAGSGQNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGG 119 Query: 152 VESMTNNYKNVNPLGMISSEELQKNREAK--KCLI-----------PMGITNENVAANFK 198 E+M+ P + S + + +AK +I MGIT ENVA + Sbjct: 120 QENMS-----AAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYG 174 Query: 199 ISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP----DGSICQSDEGPRPNVTAESL 254 I+R+ QDEFA S KA A+ G F++EI+P+ +P D ++DE R T +S+ Sbjct: 175 ITREAQDEFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSM 234 Query: 255 SSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEI 314 S ++PAF K GT TA NAS ++DG A V++ + A +L L L + GV P++ Sbjct: 235 SGLKPAFDK-AGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKV 293 Query: 315 MGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALG 374 MG+GP A + L QD+D+ EINEAFAAQAL ++G D +KVN GGAIA+G Sbjct: 294 MGMGPVPASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIG 353 Query: 375 HPLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAA 411 HP+G +G R + T+L E+K+ + G+ S+CIG GMG A Sbjct: 354 HPIGASGCRILVTLLHEMKRRDAKKGLASLCIGGGMGVA 392 >1WDK-C nrPDB Length = 390 Score = 214 bits (545), Expect = 6e-56, Method: Compositional matrix adjust. Identities = 143/394 (36%), Positives = 210/394 (53%), Gaps = 22/394 (5%) Query: 33 PEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGN 92 P DVVIV R+ +G+ G ++ + + + +++ + R + D +E+V G Sbjct: 4 PRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERNS---KVDPGEVEDVIWGC 60 Query: 93 V-LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALG 151 V + G R A L + IP+++ ++R C S ++A++ A I G D+ + G Sbjct: 61 VNQTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVGG 120 Query: 152 VESM--TNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAA 209 VE M + V+P + A K MG+T E + ISR+ QD FA Sbjct: 121 VEHMGHVSMMHGVDP-------NPHMSLYAAKASGMMGLTAEMLGKMHGISREQQDAFAV 173 Query: 210 NSYQKAYKAKNEGLFEDEILPIKLPDGS----ICQSDEGPRPNVTAESLSSIRPAFIKDR 265 S+Q A+KA EG F+DEI+P++ D + I DE RP+ T ESL++++PAF Sbjct: 174 RSHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKG 233 Query: 266 GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPK 325 GT TAG +SQ++DG + +++ A L L L GV P IMG GP A K Sbjct: 234 GTVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQK 293 Query: 326 VLEATGLQVQDIDIFEINEAFAAQALYCIHKLGI--DLN-KVNPRGGAIALGHPLGCTGA 382 L+ GL + DID E+NEAFAAQAL + L + +N KVN GGAIALGHP GC+GA Sbjct: 294 ALKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGA 353 Query: 383 RQVATILRELKKD--QIGVVSMCIGTGMGAAAIF 414 R T+L +K++ G+ +MCIG G G A +F Sbjct: 354 RISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVF 387 >4WYS-A nrPDB Length = 405 Score = 212 bits (539), Expect = 2e-55, Method: Compositional matrix adjust. Identities = 151/397 (38%), Positives = 214/397 (53%), Gaps = 24/397 (6%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 ++ VIV+A R+AIG F G+ + L + I E + D ++EV GNV Sbjct: 5 KNCVIVSAVRTAIGS-FNGSLASTSAIDLGATVIKAAI----ERAKIDSQHVDEVIMGNV 59 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R A L SG+ + +N+ C SGL +V A I+ GQ +A G+E Sbjct: 60 LQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGME 119 Query: 154 SMT-----------NNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRK 202 +M+ + Y+ + G + L+ MGIT ENVA + I+R+ Sbjct: 120 NMSLAPYLLDAKARSGYRLGD--GQVYDVILRDGLMCATHGYHMGITAENVAKEYGITRE 177 Query: 203 DQDEFAANSYQKAYKAKNEGLFEDEILPIKL---PDGSICQSDEGPRPNVTAESLSSIRP 259 QDE A +S +KA A G F EI+P+ + + DE P+ N TAE+L ++RP Sbjct: 178 MQDELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRP 237 Query: 260 AFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 AF K GT TAGNAS ++DG A +++ S A L L R + + GVPP +MG+GP Sbjct: 238 AFDK-AGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGP 296 Query: 320 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGC 379 A K L+ GLQ+ DID+ E NEAFAAQ L LG D KVN GGAIALGHP+G Sbjct: 297 VPATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGA 356 Query: 380 TGARQVATILRELK-KDQ-IGVVSMCIGTGMGAAAIF 414 +GAR + T+L ++ +D+ +G+ ++CIG G G A + Sbjct: 357 SGARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVI 393 >6BJA-A nrPDB Length = 397 Score = 210 bits (535), Expect = 9e-55, Method: Compositional matrix adjust. Identities = 139/398 (34%), Positives = 211/398 (53%), Gaps = 24/398 (6%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +DV I++A R+ I F+ ++ L E I R P A IEE GNV Sbjct: 9 KDVYILSAVRTPIAS-FRSTLTSLSAVDLGIVVTKEAIKRSLLPSSA----IEETIVGNV 63 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L+ G G R +AS IP S+ V +N+ CSS + A+ A I+VG I +ALG E Sbjct: 64 LSAGLGQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSE 123 Query: 154 SMTNN----------YKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKD 203 SM+N + V + + + L + E + PMG+ E ++ +R+ Sbjct: 124 SMSNAPFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQ----PMGLCAEKTVKDYAFTREQ 179 Query: 204 QDEFAANSYQKAYKAKNEGLFEDEILPIKLPD---GSICQSDEGPRPNVTAESLSSIRPA 260 D +A SY+KA A EG F E++P+ +P + +++ + E + ++ PA Sbjct: 180 LDAYAIESYRKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIPEKVPALHPA 239 Query: 261 FIKD-RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 F+KD GT TA NAS ++DG A +LA V + L + + + + GV P V P Sbjct: 240 FLKDGSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAP 299 Query: 320 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGC 379 A A+ ++L +GL + I ++EINEAF+ L I +L +D +VN RGGA+ALGHPLG Sbjct: 300 ALAVKQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGA 359 Query: 380 TGARQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE 417 +GAR V T++ LK D++GV ++C G G A+AI IK+ Sbjct: 360 SGARIVVTLVHALKSDELGVAAICNGGGE-ASAILIKK 396 >4C2K-A nrPDB Length = 417 Score = 209 bits (532), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 143/395 (36%), Positives = 203/395 (51%), Gaps = 24/395 (6%) Query: 36 VVIVAANRSAIGKGFKGAFKDVN-TDYLLYNFLNEFIGRFP-EPLRADLNLIEEVACGNV 93 V +VAA R+ G + G KD TD L+EF + + ++ V GNV Sbjct: 27 VFVVAAKRTPFG-AYGGLLKDFTATD------LSEFAAKAALSAGKVSPETVDSVIMGNV 79 Query: 94 LNVGAGATE-HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 L + A R L GIP TP + +NR C SG ++ + +I V + ++ L G Sbjct: 80 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 139 Query: 153 ESMTN------NYKNVNPLG--MISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQ 204 ESM+ N + LG + + L + + +PM +T EN+A KISR++ Sbjct: 140 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 199 Query: 205 DEFAANSYQKAYKAKNEGLFEDEILPIKLPDG---SICQSDEGPRPNVTAESLSSIRPAF 261 D++A S Q+ A + G F DE+ PI++ Q DE RP T E L + P F Sbjct: 200 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF 259 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 KD GT TAGNAS V+DG V++A + N L R + + G P IMG+GP Sbjct: 260 KKD-GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 318 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 AI L+ GL ++D+D+ E+NEAFA Q L L +D++K N GGAIALGHPLG +G Sbjct: 319 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 378 Query: 382 ARQVATILRELKK--DQIGVVSMCIGTGMGAAAIF 414 +R A ++ EL++ + V S CIG G G A I Sbjct: 379 SRITAHLVHELRRRGGKYAVGSACIGGGQGIAVII 413 >5LP7-H nrPDB Length = 393 Score = 208 bits (530), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 141/394 (35%), Positives = 207/394 (52%), Gaps = 26/394 (6%) Query: 37 VIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNV 96 VIV+A R+ GK F G K+V L + E + + + +E G V+ Sbjct: 5 VIVSAARTPFGK-FGGVLKEVKAAELGGIVMKEAL----QQAGVSGDDVEGNVMGMVVQA 59 Query: 97 GAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMT 156 G+G R A +G+P+S P LN+ C+SGL AV I+ DI +A G+ESM+ Sbjct: 60 GSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGMESMS 119 Query: 157 NNYKNVNPLGMISSE----ELQK--NREAKKCL---IPMGITNENVAANFKISRKDQDEF 207 N V P G + EL+ + C + M + A + ISR++QDE+ Sbjct: 120 NIPYAV-PAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQDEW 178 Query: 208 AANSYQKAYKAKNEGLFEDEILPIKL------PDGSICQSDEGPRPNVTAESLSSIRPAF 261 A S+ +A KA +EG F+DEI+P+ P+ + DE R + + + L+ + P + Sbjct: 179 ALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPN--VVDKDEAIRRDTSLDQLAKLAPIY 236 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 D G+ TAGNA V+DG +L A +L L + F T G+P + P + Sbjct: 237 ASD-GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGF 295 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 AI K+L+ GL VQDID+FE+NEAFA+ L C +G DL KVN GGAIALGHP+G +G Sbjct: 296 AINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASG 355 Query: 382 ARQVATILRELKK--DQIGVVSMCIGTGMGAAAI 413 AR + T++ ELK+ +GV ++C G G A + Sbjct: 356 ARILMTLVYELKRRGGGLGVAAICSGAAQGDAVL 389 >4B3J-C nrPDB Length = 403 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 147/406 (36%), Positives = 203/406 (50%), Gaps = 33/406 (8%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 E+ I A R+ GK G+ +V L+ ++E R P+ D NLI +V G V Sbjct: 3 EEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPD---LDENLISDVILGCV 59 Query: 94 LNVG-AGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 VG G RAA LASG+P ++ V LNR C+SGL AVN A K++ G D+ LA GV Sbjct: 60 SPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGV 119 Query: 153 ESMTNNYKNVNPLGMIS-SEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANS 211 ESM+ P+G + L +P I + +A SR+D D +A S Sbjct: 120 ESMSRV-----PMGSDGGAMGLDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRS 174 Query: 212 YQKAYKAKNEGLFEDEILPIKLPDGS-ICQSDEGPRPNVTAESLSSIRPAFI-------- 262 QKA +A + G F ++P++ +G I DE RP+ T E L+ ++PAF Sbjct: 175 QQKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALGGF 234 Query: 263 ------------KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGV 310 K T GN+S + DG A V++ + L R + T G Sbjct: 235 DDVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATATSGA 294 Query: 311 PPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGA 370 P IM GP A KVL+ GL V DID+FE+NEAFA+ L L I K+N GGA Sbjct: 295 DPVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGA 354 Query: 371 IALGHPLGCTGARQVATILRELKKDQI--GVVSMCIGTGMGAAAIF 414 IA+GHPLG TGA + T++ EL++ ++++CIG GMG A I Sbjct: 355 IAMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATII 400 >2IBU-A nrPDB Length = 395 Score = 201 bits (511), Expect = 5e-52, Method: Compositional matrix adjust. Identities = 136/395 (34%), Positives = 207/395 (52%), Gaps = 19/395 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 ++VVIV+A R+ IG F G+ + L + I + P ++E GNV Sbjct: 8 KEVVIVSATRTPIGS-FLGSLSLLPATKLGSIAIQGAIEKAGIPKEE----VKEAYMGNV 62 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R A L +G+P STP +N+ C+SG+ A+ + + G D+ +A G+E Sbjct: 63 LQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVAGGME 122 Query: 154 SMTNNYKNVN----PLGMISSEELQKNREAKKCL--IPMGITNENVAANFKISRKDQDEF 207 SM+N +N P G + E+L I MG EN A I+R +QD + Sbjct: 123 SMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNEQDAY 182 Query: 208 AANSYQKAYKAKNEGLFEDEILPIKL-----PDGSICQSDEGPRPNVTAESLSSIRPAFI 262 A NSY ++ A G F +E++P+ + PD + + +E R V + ++ F Sbjct: 183 AINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKR--VDFSKVPKLKTVFQ 240 Query: 263 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 322 K+ GT TA NAS ++DG A ++L A +LN+ L R + F V P + P YA Sbjct: 241 KENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPVYA 300 Query: 323 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 VL+ GL+ +DI ++E+NEAF+ L I L ID KVN GGA++LGHP+G +GA Sbjct: 301 ASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMSGA 360 Query: 383 RQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE 417 R V + LK+ + G+ S+C G G GA+A+ I++ Sbjct: 361 RIVGHLTHALKQGEYGLASICNGGG-GASAMLIQK 394 >5CBQ-A nrPDB Length = 413 Score = 200 bits (509), Expect = 8e-52, Method: Compositional matrix adjust. Identities = 137/402 (34%), Positives = 211/402 (52%), Gaps = 27/402 (6%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94 D VI R+ IG+ + G F+ + L L + R + AD +E+V G+ Sbjct: 11 DAVICEPVRTPIGR-YGGMFRSLTAVDLGVTALKGLLER--TGIAADQ--VEDVILGHCY 65 Query: 95 NVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 R L +G+P + P + ++R+C SGL AV +++ G D+ +A G ES Sbjct: 66 PNSEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAES 125 Query: 155 MTNNYKNVNPL-------GMISSEELQKNRE---AKKCLIPMGI--TNENVAANFKISRK 202 M+N + G+ + L + R K +P G+ T EN+ + ISR Sbjct: 126 MSNVAFYSTDMRWGGARTGVQIHDGLARGRTTAGGKFHPVPGGMLETAENLRREYHISRT 185 Query: 203 DQDEFAANSYQKAYKAKNEGLFEDEILPI--KLPDGSICQS-DEGPRPNVTAESLSSIRP 259 +QDE A S+Q+A A++EG+ +EI+P+ + DG S DE PR + T E+L+ ++P Sbjct: 186 EQDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHPRADTTVEALAKLKP 245 Query: 260 AFIKD--RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGV 317 +K T TAGN+S +D + ++ A +L L L R + + + GV P++MG+ Sbjct: 246 VLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPDLMGI 305 Query: 318 GPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGI---DLNKVNPRGGAIALG 374 GP A L GL + DID+ E+NEAFAAQAL + + D + N RG I+LG Sbjct: 306 GPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSGISLG 365 Query: 375 HPLGCTGARQVATILRELKKDQ--IGVVSMCIGTGMGAAAIF 414 HP+G TG R +AT+ REL + + G+ +MCIG G G AA+F Sbjct: 366 HPVGATGGRMLATLARELHRREARYGLETMCIGGGQGLAAVF 407 >6ARG-A nrPDB Length = 399 Score = 197 bits (500), Expect = 1e-50, Method: Compositional matrix adjust. Identities = 141/398 (35%), Positives = 214/398 (53%), Gaps = 25/398 (6%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 V IV++ R+ +G F G+ + L + + + + +D ++EV GNV++ Sbjct: 8 VYIVSSARTPVGS-FLGSLSSLTAPQLGAHAIKAALAKVDGLKPSD---VQEVFFGNVIS 63 Query: 96 VGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESM 155 G R L +G+ ST +N+ C+SGL A+ A I G D+ +A G ESM Sbjct: 64 ANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESM 123 Query: 156 TN------NYKNVNPLGMIS-SEELQKN--REAKKCLIPMGITNENVAANFKISRKDQDE 206 +N N + G S + + K+ +A K + MG+ E A + SR+ QDE Sbjct: 124 SNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQEL-MGLQAEECAQDHGFSREQQDE 182 Query: 207 FAANSYQKAYKAKNEGLFEDEILPIKL------PDGSICQSDEGPRPNVTAESLSSIRPA 260 +A +Y+KA A+ GLF++EI PI+L PD ++ Q DE P+ N+ E L +I+PA Sbjct: 183 YAIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQ-DEEPK-NLNPEKLRAIKPA 240 Query: 261 FIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPA 320 FI GT TA N+S ++DG A V+L + +LNL + + + + P PA Sbjct: 241 FIPGSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPA 300 Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCT 380 AIPK L+ G+ ID FEINEAF+ AL + LGI KVN GGA+A+GHP+G + Sbjct: 301 LAIPKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGAS 360 Query: 381 GARQVATILREL--KKDQIGVVSMCIGTGMGAAAIFIK 416 GAR + T+L L KK ++G +C G G GA+A+ ++ Sbjct: 361 GARILTTLLGVLKAKKGKLGCAGICNGGG-GASALVVE 397 >3SVK-A nrPDB Length = 407 Score = 196 bits (497), Expect = 2e-50, Method: Compositional matrix adjust. Identities = 142/405 (35%), Positives = 200/405 (49%), Gaps = 31/405 (7%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 E+ I A R+ GK G+ +V L+ ++E R+P+ D LI ++ G V Sbjct: 7 EEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPD---LDETLISDMILGVV 63 Query: 94 LNVG-AGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 VG G R A LA+G+P +T V LNR C+SGL AVN A K++ G D+ LA GV Sbjct: 64 SPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGV 123 Query: 153 ESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSY 212 ESM+ + + E + +P GI + +A SR+D D +A S Sbjct: 124 ESMSRVPMGSDGGAWATDPETNY----RIGFVPQGIGADLIATLEGFSREDVDAYALRSQ 179 Query: 213 QKAYKAKNEGLFEDEILPIKLPDG-SICQSDEGPRPNVTAESLSSIRPAF--IKDRG--- 266 QKA A + G F ++P++ +G I DE RP+ T E L+ ++ AF + + G Sbjct: 180 QKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMRPDTTMEGLAKLKTAFDGVGEMGGFD 239 Query: 267 ---------------TTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVP 311 T GN+S + DG A VL+ L R + T G Sbjct: 240 DVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRARIVATATSGSD 299 Query: 312 PEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAI 371 P IM GP A KVL+ GL + DID+FE+NEAFA+ L L I K+N GGAI Sbjct: 300 PVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGAI 359 Query: 372 ALGHPLGCTGARQVATILRELKKDQI--GVVSMCIGTGMGAAAIF 414 A+GHPLG TGA T++ EL++ ++++CIG GMG A I Sbjct: 360 AMGHPLGATGAMITGTMVDELERRNARRALITLCIGGGMGVATII 404 >5XYJ-B nrPDB Length = 408 Score = 192 bits (487), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 138/401 (34%), Positives = 210/401 (52%), Gaps = 23/401 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 ++V IV+ R+ IG F+G+ L L + + PE L A + +E+ GNV Sbjct: 13 QNVYIVSTARTPIGS-FQGSLSSKTAVELGAVALKGALAKVPE-LDASKDF-DEIIFGNV 69 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L+ G R LA+G+ +N+ +S + A+ A IK G D+ +A G E Sbjct: 70 LSANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVAGGCE 129 Query: 154 SMTNN--YKNVNPLGMISSEELQKNREAKKCL------IPMGITNENVAANFKISRKDQD 205 SMTN Y G + + + + L + MG+ E A ++ I+R+ QD Sbjct: 130 SMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITREQQD 189 Query: 206 EFAANSYQKAYKAKNEGLFEDEILPIKL------PDGSICQSDEGPRPNVTAESLSSIRP 259 FA SYQK+ K++ EG F++EI+P+ + PD + + +E R +V E L S R Sbjct: 190 NFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHV--EKLRSART 247 Query: 260 AFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 F K+ GT TA NAS ++DG A V+L V + NL L + P P Sbjct: 248 VFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADFTWAP 307 Query: 320 AYAIPKVLEATGLQ-VQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLG 378 + A+PK L+ G++ + +D FE NEAF+ L L +D +KVN GGA+ALGHPLG Sbjct: 308 SLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALGHPLG 367 Query: 379 CTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIKE 417 C+GAR V T+L L+++ +IGV ++C G G GA++I I++ Sbjct: 368 CSGARVVVTLLSILQQEGGKIGVAAICNGGG-GASSIVIEK 407 >6BN2-A nrPDB Length = 401 Score = 192 bits (487), Expect = 3e-49, Method: Compositional matrix adjust. Identities = 119/344 (34%), Positives = 189/344 (54%), Gaps = 13/344 (3%) Query: 85 IEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQI 144 I++V GNVL G G + A L +G+P +TP A+N+ C+SG+ AV A +K G + Sbjct: 56 IQDVYMGNVLQAGEGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDV 115 Query: 145 DIGLALGVESMTN-----NYKNVNPLGMISSEE--LQKNREAKKCLIPMGITNENVAANF 197 + +A G+E+M+ + +N LG I ++ L+ MG E A + Sbjct: 116 EAIVAGGMENMSQVPHYIDGRNGVKLGDIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEY 175 Query: 198 KISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESL 254 I+R++QD FA SY+++ KA +EG F++E++P+ +P I +++ NV + + Sbjct: 176 NITREEQDAFAIQSYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNVKFDRI 235 Query: 255 SSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEI 314 ++ F K+ GT TA NAS ++DG + ++L + L L L + + + PE Sbjct: 236 PTLPTVFQKENGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEW 295 Query: 315 MGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALG 374 PA A+P L L + DID FE NEAF+ L LG+D KVN GGA+ALG Sbjct: 296 FTTAPAKALPIALAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALG 355 Query: 375 HPLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 HPLG +G+R + T++ LK++ + G ++C G G GA+AI I+ Sbjct: 356 HPLGSSGSRIIVTLINVLKQNNAKYGAAAICNGGG-GASAIVIE 398 >6BJB-A nrPDB Length = 393 Score = 187 bits (474), Expect = 9e-48, Method: Compositional matrix adjust. Identities = 132/392 (33%), Positives = 204/392 (52%), Gaps = 37/392 (9%) Query: 32 RP-EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADL-------N 83 RP DVV V A R+ IG F+ AF +V L GR E L+ L + Sbjct: 5 RPITDVVFVGAARTPIGS-FRSAFNNVPVTVL---------GR--EALKGALKNANVKPS 52 Query: 84 LIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQ 143 L++E G V+ AG R L +G ST A+N+ +SG+ A+ A+ +++ Sbjct: 53 LVQEAFIGVVVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDL 112 Query: 144 IDIGLALGVESMTN----------NYKNVNPLGMISSEELQKNREAKKCLIPMGITNENV 193 ++ +A G+ESM+ + + I + L I MG + V Sbjct: 113 QEMVVAGGMESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYND----ILMGACADKV 168 Query: 194 AANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDG--SICQSDEGPRPNVTA 251 A F I+R++QD++A SY+++ A EG+F EI+P+++ G +I ++ V Sbjct: 169 AKQFAITREEQDKYAILSYKRSAAAWKEGIFAKEIIPLEVTQGKKTITVEEDEEYKKVNF 228 Query: 252 ESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVP 311 E + ++PAF + G+ TA NAS ++DG A V++ A + L L R + + Sbjct: 229 EKIPKLKPAFTSE-GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATH 287 Query: 312 PEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAI 371 P G+ PA IPKVL+ GLQ++DID++EINEAFA LY + LG+D +KVN GGA+ Sbjct: 288 PIDFGIAPASVIPKVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAV 347 Query: 372 ALGHPLGCTGARQVATILRELKKDQIGVVSMC 403 +LGHP+G +GAR V ++ LK Q G ++C Sbjct: 348 SLGHPIGMSGARIVGHLVHTLKPGQKGCAAIC 379 >4UBW-A nrPDB Length = 399 Score = 169 bits (427), Expect = 3e-42, Method: Compositional matrix adjust. Identities = 131/393 (33%), Positives = 186/393 (47%), Gaps = 24/393 (6%) Query: 37 VIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNV 96 VIV A RS IGK G ++ LL + + +E+V G V Sbjct: 13 VIVEATRSPIGK-RNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQF 71 Query: 97 GAGATE-HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESM 155 G + R A L +G+P ++ QC SG A + IA I G ID+G+A G+E+M Sbjct: 72 GEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAM 131 Query: 156 TNNY--KNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQ 213 + N P L + + L E +A I+R+D D F S + Sbjct: 132 SRVGLGANAGP-----DRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVDVFGLESQR 186 Query: 214 KAYKAKNEGLFEDEILPIKLP----------DGSICQSDEGPRPNVTAESLSSIRPAFIK 263 +A +A EG F+ EI PI+ P + + D+G R T L ++P Sbjct: 187 RAQRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLGELKPVL-- 243 Query: 264 DRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAI 323 + G TAG +SQ+SDG A VL +VA L R + VG P GP + Sbjct: 244 EGGIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPVQST 303 Query: 324 PKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGAR 383 KVLE G+++ DIDI EINEAFA+ L D+++VN GGAIALGHP+GCTG+R Sbjct: 304 AKVLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSR 363 Query: 384 QVATILRELKK-DQ-IGVVSMCIGTGMGAAAIF 414 + T L EL++ DQ + +++MC G + I Sbjct: 364 LITTALHELERTDQSLALITMCAGGALSTGTII 396 >5ZQZ-B nrPDB Length = 474 Score = 159 bits (402), Expect = 2e-39, Method: Compositional matrix adjust. Identities = 133/438 (30%), Positives = 199/438 (45%), Gaps = 53/438 (12%) Query: 21 ESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRA 80 ++K K +L + +VV+V R+ ++KD+ L L + R P Sbjct: 39 QTKTKKTLAKPNIRNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTSVPK-- 95 Query: 81 DLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIK 140 +++ + G V+ + R A L +G TP + C S A+ I Sbjct: 96 --EVVDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTGVGLIA 153 Query: 141 VGQIDIGLALGVESMT-----------------NNYKNV-NPLGMIS-------SEELQK 175 GQ D+ +A GVE M+ N K++ L +IS + EL Sbjct: 154 SGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLAPELPA 213 Query: 176 NREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPD 235 E MG + + +AA F +SR +QDE+A S+ A KA++EGL D ++P K+P Sbjct: 214 VSEFSTSET-MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVPFKVPG 271 Query: 236 GSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLN 295 D G RP+ + E ++ ++PAFIK GT TA N+S ++DG + +L+ A + Sbjct: 272 KDTVTKDNGIRPS-SLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEKALAMG 330 Query: 296 LPVLGRYIDFQTVGV-PPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCI 354 DF V P + + +GP YA PKVLE GL + DID FE +EAF+ Q L Sbjct: 331 YKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQILANF 390 Query: 355 HKLGID-----------------LNKVNPRGGAIALGHPLGCTGARQVATILRELKKD-- 395 + D L K N GG+++LGHP G TG R V L+K+ Sbjct: 391 KAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRLRKEGG 450 Query: 396 QIGVVSMCIGTGMGAAAI 413 Q G+V+ C G G A I Sbjct: 451 QYGLVAACAAGGQGHAMI 468 >5LNQ-A nrPDB Length = 457 Score = 60.5 bits (145), Expect = 1e-09, Method: Compositional matrix adjust. Identities = 71/313 (22%), Positives = 121/313 (38%), Gaps = 57/313 (18%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKN 176 P + + +SG AV N +K G DI LA+GVE T V + + + Q+ Sbjct: 131 PAMRVEGAAASGGLAVISAMNALKSGSADITLAVGVEVQTTASARVGGDYLARAADYQRQ 190 Query: 177 REAKKCLIPMGITN--ENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP 234 R+ P + +A + + +D AA +Y K + ++ Sbjct: 191 RQLDDFTFPCLFAKRMKYIAEHNHFTMEDTARVAAKAYANGNKNPLAHMHTRKL------ 244 Query: 235 DGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTT------AGNASQVSDGVAGVLLARR 288 T E + P+ +K G T + SQVSDG AGV+LA Sbjct: 245 ---------------TFEQCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANE 289 Query: 289 SVANQLNL-PVLGRYIDFQTVGVPPEIMGVGP---------AYAIPKVLEATGLQVQDID 338 ++ L P R ++ +++ + P A K L ++ D++ Sbjct: 290 EGLRKMGLSPNDSRLVEIKSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLN 349 Query: 339 IFEINEAFAAQALYCIHKLGI-------DLNK-----------VNPRGGAIALGHPLGCT 380 + E+++ F + LGI DL + VN GG ++ GHP+G T Sbjct: 350 VAEVHDCFTIAEMLMYEALGIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPVGAT 409 Query: 381 GARQVATILRELK 393 G +Q+ + R++K Sbjct: 410 GIKQIMEVYRQMK 422 >6ESQ-A nrPDB Length = 392 Score = 50.4 bits (119), Expect = 1e-06, Method: Compositional matrix adjust. Identities = 90/409 (22%), Positives = 153/409 (37%), Gaps = 101/409 (24%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV- 93 DV I+ ++ G+ ++ +F+D+ + E + + D I+ + GN+ Sbjct: 3 DVAIIGYGQTKFGELWEDSFRDL---------IVEAGVKAIKDANVDGGDIDAMYIGNMS 53 Query: 94 --LNVGAGATEHRAACLASGIPYS-TPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 L VG EH A+ +A + P + C+SG A+ + G D+ LA Sbjct: 54 GGLFVG---QEHIASLIADHAGLNPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAG 110 Query: 151 GVESMTNNYKNVNPLGMISSEELQK----------NREAKKCLIPMGITNENVAANFKIS 200 GVE MT+ + S +E + A++ + G+T E ++ I+ Sbjct: 111 GVEKMTDVEDATAAIASASDQEWEAFFGATFPSLYAMMARRYMYQYGLTIEELSMWSVIA 170 Query: 201 RKDQDEFAANSY-QKAYKAKNEGLFEDEIL--PIKL------PDGS----ICQSDEGPRP 247 ++ + N Y Q +K E + + P+ L DG+ +C +D+ Sbjct: 171 HENATK---NKYAQFGFKTTLEQVMNASPVADPLTLMHCSPVSDGASALIVCDADKAEEF 227 Query: 248 NVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQT 307 E + +IK ++Q SD +A L R LN + ++ Sbjct: 228 APKDEII------YIK--------ASTQASDTIA---LHDREDMTTLNAAKVASEKAYKL 270 Query: 308 VGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGI-------- 359 + PE ID+ E+++ FA L + LG Sbjct: 271 AKIAPE----------------------KIDVAEVHDCFAINGLILVEDLGFCKKGDAGK 308 Query: 360 ------------DLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQ 396 D VNP GG A GH LG TG RQV + +LK+D+ Sbjct: 309 VIDEGKIRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQDK 357 >4BI9-A nrPDB Length = 454 Score = 49.3 bits (116), Expect = 3e-06, Method: Compositional matrix adjust. Identities = 76/326 (23%), Positives = 124/326 (38%), Gaps = 50/326 (15%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKN 176 P V + C+SG AV + G I LA+GVE T V + + ++ Sbjct: 128 PAVRVEGACASGGLAVQSAWEALLAGTSQIALAVGVEVQTTVSARVGGDYLARAAHYKRQ 187 Query: 177 REAKK----CLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIK 232 R+ CL + A +F + +D + A +N L + Sbjct: 188 RQLDDFTFPCLFARRMKAIQEAGHFTM----EDAAYVAAKAYASGNRNP-LAHMHARKVT 242 Query: 233 LPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVAN 292 L C PN + I F++ TT + SQVSDG A V+LA Sbjct: 243 L---DFCTQASDKNPNFLG---NEIYKPFLR----TT--DCSQVSDGGAAVILASEEGLQ 290 Query: 293 QLNL-PVLGRYIDFQTVGV--------PPEIMGVGPAYAIPKV-LEATGLQVQDIDIFEI 342 +L L P R ++ +++ P++ + + + L G++ + + + E+ Sbjct: 291 KLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMVAARTALSMAGVKPEQLQVAEV 350 Query: 343 NEAFAAQALYCIHKLGIDLN------------------KVNPRGGAIALGHPLGCTGARQ 384 ++ F L LGI VN GG ++ GHP+G TG +Q Sbjct: 351 HDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIPVNTGGGLLSFGHPVGATGVKQ 410 Query: 385 VATILRELKKDQIGVVSMCIGTGMGA 410 V + R++ K Q G M G+GA Sbjct: 411 VLEVYRQM-KGQCGEYQMKNIPGIGA 435 >6HRV-A nrPDB Length = 421 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 27/92 (29%), Positives = 43/92 (46%), Gaps = 18/92 (19%) Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLG----------IDLNK-------- 363 A + + G++ D+D+ E+++ F+A L LG ID Sbjct: 285 AAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGELIDRGDNTYGGKWV 344 Query: 364 VNPRGGAIALGHPLGCTGARQVATILRELKKD 395 +NP GG I+ GHPLG TG Q A + +L+ + Sbjct: 345 INPSGGLISKGHPLGATGLAQCAELCWQLRAE 376 >4YZO-A nrPDB Length = 373 Score = 33.5 bits (75), Expect = 0.18, Method: Compositional matrix adjust. Identities = 24/92 (26%), Positives = 42/92 (45%), Gaps = 11/92 (11%) Query: 332 LQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATIL-- 389 +Q +DI +F+ E + A + + L ++ +NP GG + GHP+G +G Q Sbjct: 279 IQSEDIGLFKKGEGWKA-VMEGLTSLDGEI-PINPSGGLNSKGHPIGASGVAQAVEAFSQ 336 Query: 390 -------RELKKDQIGVVSMCIGTGMGAAAIF 414 R++K ++G+ G G A I Sbjct: 337 IRNEAGNRQVKNARVGLSLSMAGYGNSATVII 368 >1XKH-A nrPDB Length = 687 Score = 32.0 bits (71), Expect = 0.47, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 16/94 (17%) Query: 264 DRGTTTAGNASQVSDG----VAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 D G G SQ D + + AR +V + LNL + GR +D++ G+ P I G Sbjct: 381 DIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGR 440 Query: 320 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYC 353 IP V ++++N+ ++ A Y Sbjct: 441 --FIPYVGA----------VYDLNDTYSVYASYT 462 >2W78-A nrPDB Length = 772 Score = 31.6 bits (70), Expect = 0.58, Method: Compositional matrix adjust. Identities = 25/94 (26%), Positives = 41/94 (43%), Gaps = 16/94 (17%) Query: 264 DRGTTTAGNASQVSDG----VAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP 319 D G G SQ D + + AR +V + LNL + GR +D++ G+ P I G Sbjct: 466 DIGKPDWGTPSQYIDDKTRQLGSYMTARFNVTDDLNLFLGGRVVDYRVTGLNPTIRESGR 525 Query: 320 AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYC 353 IP V ++++N+ ++ A Y Sbjct: 526 --FIPYVGA----------VYDLNDTYSVYASYT 547 >1UXV-A nrPDB Length = 501 Score = 30.0 bits (66), Expect = 1.8, Method: Compositional matrix adjust. Identities = 26/89 (29%), Positives = 44/89 (49%), Gaps = 11/89 (12%) Query: 317 VGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHP 376 +GP Y P ++EA +V+D+ +++ E FA AL K DL++ +A G P Sbjct: 369 LGPTYVQPTLVEAPADRVKDMVLYK-REVFAPVALAVEVK---DLDQAI----ELANGRP 420 Query: 377 LGCTGA---RQVATILRELKKDQIGVVSM 402 G A R V I R ++ ++G + + Sbjct: 421 YGLDAAVFGRDVVKIRRAVRLLEVGAIYI 449 >3E60-A nrPDB Length = 424 Score = 30.0 bits (66), Expect = 2.0, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 19/33 (57%) Query: 125 CSSGLTAVNDIANKIKVGQIDIGLALGVESMTN 157 CS+G A+ D A I +G D+ LA G ES N Sbjct: 174 CSTGAHAIGDAARLIALGDADVMLAGGTESPIN 206 >2HGS-A nrPDB Length = 474 Score = 30.0 bits (66), Expect = 2.1, Method: Compositional matrix adjust. Identities = 34/130 (26%), Positives = 60/130 (46%), Gaps = 14/130 (10%) Query: 111 GIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISS 170 G+ TP A++R S L+ + A KI GLALG+ Y + N L ++ + Sbjct: 154 GLASRTP--AVHRHVLSVLSKTKE-AGKILSNNPSKGLALGIAKAWELYGSPNALVLLIA 210 Query: 171 EELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFED--EI 228 +E ++N ++ I NE +A N + R+ ++ + +K ++ LF D EI Sbjct: 211 QEKERNIFDQRA-----IENELLARNIHVIRRTFEDIS----EKGSLDQDRRLFVDGQEI 261 Query: 229 LPIKLPDGSI 238 + DG + Sbjct: 262 AVVYFRDGYM 271 >5M3K-C nrPDB Length = 398 Score = 29.3 bits (64), Expect = 3.5, Method: Compositional matrix adjust. Identities = 21/82 (25%), Positives = 36/82 (43%), Gaps = 17/82 (20%) Query: 331 GLQVQDIDIFEINEAFAA--------------QALYCIHKLGIDLN---KVNPRGGAIAL 373 G+ +DID+ ++ + A QA + + GI L+ +N GG I Sbjct: 286 GITAKDIDVAQVYDLLGAGLIQMESMGICGKGQAGDFVLEGGIALDGQLPLNTDGGNIGR 345 Query: 374 GHPLGCTGARQVATILRELKKD 395 GH GC G + + R+L+ + Sbjct: 346 GHASGCDGILHITELFRQLRGE 367 >5LFK-A nrPDB Length = 298 Score = 28.5 bits (62), Expect = 5.9, Method: Compositional matrix adjust. Identities = 23/80 (28%), Positives = 42/80 (52%), Gaps = 9/80 (11%) Query: 76 EPLRADLNLIEEVACGNVLN---VGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAV 132 +P R N +EVA GN+ + AG E LA+G ++ AL R +S + Sbjct: 29 KPARKLKNAADEVAQGNLRQHPELEAGPQE----FLAAGASFNQVVTALERMMTSQQRLL 84 Query: 133 NDIANKIK--VGQIDIGLAL 150 +DI+++++ + ++ +G AL Sbjct: 85 SDISHELRTPLTRLQLGTAL 104 >4JRH-A nrPDB Length = 417 Score = 28.1 bits (61), Expect = 7.7, Method: Compositional matrix adjust. Identities = 17/51 (33%), Positives = 24/51 (47%), Gaps = 6/51 (11%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGM 167 P +A++ C++GL + A I G D +A G E K PLGM Sbjct: 159 PNIAISTACTTGLHNIGHAARMIAYGDADAMVAGGAE------KASTPLGM 203 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 1PXT-A nrPDB 517 e-147 4N44-A nrPDB 470 e-133 4E1L-A nrPDB 462 e-130 4DD5-A nrPDB 449 e-126 1WL4-A nrPDB 445 e-125 2IBU-A nrPDB 443 e-125 3SS6-A nrPDB 442 e-125 1WDK-C nrPDB 440 e-124 2WUA-A nrPDB 440 e-124 6BN2-A nrPDB 439 e-124 2IIK-A nrPDB 437 e-123 1NL7-A nrPDB 436 e-123 2C7Y-A nrPDB 436 e-122 1ULQ-A nrPDB 434 e-122 3GOA-A nrPDB 433 e-122 4O9A-A nrPDB 425 e-119 4WYS-A nrPDB 424 e-119 4C2K-A nrPDB 420 e-118 4NZS-A nrPDB 420 e-118 3SVK-A nrPDB 417 e-117 5CBQ-A nrPDB 411 e-115 6ARG-A nrPDB 411 e-115 4B3J-C nrPDB 410 e-115 5XYJ-B nrPDB 408 e-114 6BJA-A nrPDB 407 e-114 5LP7-H nrPDB 404 e-113 6BJB-A nrPDB 395 e-110 5ZQZ-B nrPDB 391 e-109 4UBW-A nrPDB 376 e-104 5LNQ-A nrPDB 235 2e-62 6ESQ-A nrPDB 226 1e-59 4BI9-A nrPDB 211 4e-55 6HRV-A nrPDB 148 4e-36 Sequences not found previously or not previously below threshold: 4YZO-A nrPDB 105 4e-23 5M3K-C nrPDB 77 2e-14 4U4E-A nrPDB 64 9e-11 3O04-A nrPDB 51 8e-07 5W2O-A nrPDB 50 2e-06 4R8E-A nrPDB 48 5e-06 4QAV-A nrPDB 48 6e-06 6QSP-A nrPDB 48 8e-06 1J3N-A nrPDB 47 1e-05 2GP6-A nrPDB 47 2e-05 3E60-A nrPDB 46 3e-05 4EWP-A nrPDB 44 1e-04 4LS7-A nrPDB 44 1e-04 2IX4-A nrPDB 44 1e-04 2GQD-A nrPDB 43 2e-04 3KZU-A nrPDB 43 2e-04 1OXH-A nrPDB 43 2e-04 4DDO-A nrPDB 42 4e-04 4JRH-A nrPDB 40 0.002 4JGA-A nrPDB 40 0.002 4JPF-A nrPDB 40 0.003 4RYB-A nrPDB 39 0.004 2IWZ-A nrPDB 39 0.004 3HO9-A nrPDB 39 0.005 4DFE-A nrPDB 38 0.006 5AB6-A nrPDB 37 0.013 1MZJ-A nrPDB 37 0.021 5BY7-A nrPDB 36 0.032 4X0O-A nrPDB 35 0.056 4OQJ-A nrPDB 35 0.067 1E5M-A nrPDB 35 0.072 2BZ4-A nrPDB 35 0.088 5ENY-A nrPDB 35 0.091 4XOX-A nrPDB 34 0.14 1TQY-A nrPDB 34 0.14 1UB7-A nrPDB 34 0.15 6ET0-A nrPDB 33 0.27 4YLT-A nrPDB 32 0.37 5O31-R nrPDB 32 0.41 4YUC-A nrPDB 32 0.46 5VXG-A nrPDB 32 0.46 5GUP-F nrPDB 32 0.46 3IL4-A nrPDB 32 0.48 5YO9-A nrPDB 32 0.57 3H76-A nrPDB 32 0.62 6G2J-R nrPDB 32 0.64 2EBD-A nrPDB 32 0.76 5OQL-X nrPDB 31 0.80 3OA3-A nrPDB 31 0.80 2AJ9-A nrPDB 31 0.80 5XTD-T nrPDB 31 0.88 3OYT-A nrPDB 31 0.92 1DXL-A nrPDB 31 0.97 4V2P-A nrPDB 31 1.00 5BQS-A nrPDB 31 1.1 3IL7-A nrPDB 30 1.7 4NHD-A nrPDB 30 1.8 3VEW-A nrPDB 30 2.0 5OQL-Y nrPDB 30 2.3 2DVM-A nrPDB 30 2.3 5C6U-A nrPDB 30 2.7 5BNS-A nrPDB 30 2.7 4EB0-A nrPDB 29 3.6 5IPW-A nrPDB 29 4.5 2P1R-A nrPDB 28 5.7 2X3E-A nrPDB 28 5.8 5LVW-A nrPDB 28 6.3 4EGJ-A nrPDB 28 7.3 6ET3-B nrPDB 28 7.4 2IVO-A nrPDB 28 9.6 >1PXT-A nrPDB Length = 390 Score = 517 bits (1332), Expect = e-147, Method: Composition-based stats. Identities = 390/390 (100%), Positives = 390/390 (100%) Query: 28 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE 87 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE Sbjct: 1 LLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEE 60 Query: 88 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG 147 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG Sbjct: 61 VACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIG 120 Query: 148 LALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF 207 LALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF Sbjct: 121 LALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF 180 Query: 208 AANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGT 267 AANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGT Sbjct: 181 AANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGT 240 Query: 268 TTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVL 327 TTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVL Sbjct: 241 TTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVL 300 Query: 328 EATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVAT 387 EATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVAT Sbjct: 301 EATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVAT 360 Query: 388 ILRELKKDQIGVVSMCIGTGMGAAAIFIKE 417 ILRELKKDQIGVVSMCIGTGMGAAAIFIKE Sbjct: 361 ILRELKKDQIGVVSMCIGTGMGAAAIFIKE 390 >4N44-A nrPDB Length = 400 Score = 470 bits (1210), Expect = e-133, Method: Composition-based stats. Identities = 145/396 (36%), Positives = 211/396 (53%), Gaps = 19/396 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 ++VVI +A R+AIG + + KDV L + E + + + EV GNV Sbjct: 2 KEVVIASAVRTAIGS-YGKSLKDVPAVDLGATAIKEAVKKA----GIKPEDVNEVILGNV 56 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R A +G+P P + +N+ C SGL V+ A IK G D+ +A G+E Sbjct: 57 LQAGLGQNPARQASFKAGLPVEIPAMTINKVCGSGLRTVSLAAQIIKAGDADVIIAGGME 116 Query: 154 SMTNNYKNVN--------PLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQD 205 +M+ N E + MGIT EN+A + ISR++QD Sbjct: 117 NMSRAPYLANNARWGYRMGNAKFVDEMITDGLWDAFNDYHMGITAENIAERWNISREEQD 176 Query: 206 EFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIRPAFI 262 EFA S +KA +A G F+DEI+P+ + + +DE PR T E L+ ++PAF Sbjct: 177 EFALASQKKAEEAIKSGQFKDEIVPVVIKGRKGETVVDTDEHPRFGSTIEGLAKLKPAFK 236 Query: 263 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 322 KD GT TAGNAS ++D A +++ A +L + L + + + + GV P IMG GP YA Sbjct: 237 KD-GTVTAGNASGLNDCAAVLVIMSAEKAKELGVKPLAKIVSYGSAGVDPAIMGYGPFYA 295 Query: 323 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 +E G V ++D+ E NEAFAAQ+L L D+NKVN GGAIALGHP+G +GA Sbjct: 296 TKAAIEKAGWTVDELDLIESNEAFAAQSLAVAKDLKFDMNKVNVNGGAIALGHPIGASGA 355 Query: 383 RQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 R + T++ ++K + G+ ++CIG G G A + K Sbjct: 356 RILVTLVHAMQKRDAKKGLATLCIGGGQGTAILLEK 391 >4E1L-A nrPDB Length = 395 Score = 462 bits (1190), Expect = e-130, Method: Composition-based stats. Identities = 152/397 (38%), Positives = 223/397 (56%), Gaps = 20/397 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +DVVIV+A R+ IG F G FK+ + L + E I R +L+ I+EV GNV Sbjct: 5 KDVVIVSAVRTPIGS-FGGVFKNTSAVQLGTIAVKEAISRV----GLNLSEIDEVIIGNV 59 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R + +GIP S P +N+ C SGL +V A I G+ D+ +A G E Sbjct: 60 LQTGLGQNVARQIAINAGIPNSVPSYTVNKLCGSGLKSVQLAAQSITSGENDVVIAGGTE 119 Query: 154 SMTNNY------KNVNPLGMIS--SEELQKNREAKKCLIPMGITNENVAANFKISRKDQD 205 +M+ + + +G I+ L MGIT EN+A F+ +R+ QD Sbjct: 120 NMSQAPYIVPTARFGSKMGNITMVDSMLTDGLIDAFNQYHMGITAENIATKFEFTREMQD 179 Query: 206 EFAANSYQKAYKAKNEGLFEDEILPIKL--PDGSI--CQSDEGPRPNVTAESLSSIRPAF 261 + A S KA A F++EI+P+ + G I DE P+ +T E LS ++PAF Sbjct: 180 KLALESQNKAENAIKNNRFKEEIVPVDVLIRRGKIETIDKDEYPKLGMTFEGLSKLKPAF 239 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 KD GT TAGNAS ++DG A ++L + A++L + L + + + GV PE+MG GP Sbjct: 240 KKD-GTVTAGNASGINDGAAMLILMSQQKADELGIRPLAKIKSYASAGVEPEVMGTGPIP 298 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 A K L+ GL + DID+ E NEAFAAQAL ++L ID +K+N GGAIALGHP+G +G Sbjct: 299 ATRKALKKAGLSINDIDLIEANEAFAAQALAVKNELQIDSSKLNVNGGAIALGHPIGASG 358 Query: 382 ARQVATILRELKKDQI--GVVSMCIGTGMGAAAIFIK 416 AR + T++ E++K ++ G+ ++CIG G G + + + Sbjct: 359 ARILVTLIYEMQKRKVETGLATLCIGGGQGISMVVSR 395 >4DD5-A nrPDB Length = 396 Score = 449 bits (1154), Expect = e-126, Method: Composition-based stats. Identities = 153/398 (38%), Positives = 218/398 (54%), Gaps = 19/398 (4%) Query: 32 RPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACG 91 +VVI +A R+A+G F GAFK V+ L E I R ++I+E G Sbjct: 5 NMREVVIASAARTAVGS-FGGAFKSVSAVELGVTAAKEAIKRA----NITPDMIDESLLG 59 Query: 92 NVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALG 151 VL G G R L +GIP P + +N C SGL +V+ + I +G DI L G Sbjct: 60 GVLTAGLGQNIARQIALGAGIPVEKPAMTINIVCGSGLRSVSMASQLIALGDADIMLVGG 119 Query: 152 VESMTNNYKNVN--------PLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKD 203 E+M+ + V ++ MGIT EN+A + I+R++ Sbjct: 120 AENMSMSPYLVPSARYGARMGDAAFVDSMIKDGLSDIFNNYHMGITAENIAEQWNITREE 179 Query: 204 QDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIRPA 260 QDE A S KA KA+ EG F++EI+P+ + + DE +P T E L+ +RPA Sbjct: 180 QDELALASQNKAEKAQAEGKFDEEIVPVVIKGRKGDTVVDKDEYIKPGTTMEKLAKLRPA 239 Query: 261 FIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPA 320 F KD GT TAGNAS ++DG A +++ + A +L + L + + T GV P+IMG GP Sbjct: 240 FKKD-GTVTAGNASGINDGAAMLVVMAKEKAEELGIEPLATIVSYGTAGVDPKIMGYGPV 298 Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCT 380 A K LEA + ++DID+ E NEAFAAQ++ I L ID+NKVN GGAIA+GHP+GC+ Sbjct: 299 PATKKALEAANMTIEDIDLVEANEAFAAQSVAVIRDLNIDMNKVNVNGGAIAIGHPIGCS 358 Query: 381 GARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 GAR + T+L E+K+ + G+ ++CIG GMG I + Sbjct: 359 GARILTTLLYEMKRRDAKTGLATLCIGGGMGTTLIVKR 396 >1WL4-A nrPDB Length = 397 Score = 445 bits (1145), Expect = e-125, Method: Composition-based stats. Identities = 145/397 (36%), Positives = 208/397 (52%), Gaps = 18/397 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 + VVIV+A R+ IG F GA V L + E + R + EV G+V Sbjct: 6 DPVVIVSAARTIIGS-FNGALAAVPVQDLGSTVIKEVLKRAT----VAPEDVSEVIFGHV 60 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R A + +GIPYS P + C SGL AV I +G I +A G+E Sbjct: 61 LAAGCGQNPVRQASVGAGIPYSVPAWSCQMICGSGLKAVCLAVQSIGIGDSSIVVAGGME 120 Query: 154 SMTNNYKNVNPLGMISSEELQ-------KNREAKKCLIPMGITNENVAANFKISRKDQDE 206 +M+ + E+ MGIT ENVA +++SR+DQD+ Sbjct: 121 NMSKAPHLAYLRTGVKIGEMPLTDSILCDGLTDAFHNCHMGITAENVAKKWQVSREDQDK 180 Query: 207 FAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIRPAFIK 263 A S + A+ G F+ EI+P+ + ++DE PR E++S ++P F+ Sbjct: 181 VAVLSQNRTENAQKAGHFDKEIVPVLVSTRKGLIEVKTDEFPRHGSNIEAMSKLKPYFLT 240 Query: 264 DR-GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 322 D GT T NAS ++DG A V+L ++S A++ L L R + + VGV P IMG+GP A Sbjct: 241 DGTGTVTPANASGINDGAAAVVLMKKSEADKRGLTPLARIVSWSQVGVEPSIMGIGPIPA 300 Query: 323 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 I + + G ++D+DIFEINEAFAA + + +LG++ KVN GGAIALGHPLG +G Sbjct: 301 IKQAVTKAGWSLEDVDIFEINEAFAAVSAAIVKELGLNPEKVNIEGGAIALGHPLGASGC 360 Query: 383 RQVATILRELKK--DQIGVVSMCIGTGMGAAAIFIKE 417 R + T+L L++ GV ++CIG GMG A +E Sbjct: 361 RILVTLLHTLERMGRSRGVAALCIGGGMGIAMCVQRE 397 >2IBU-A nrPDB Length = 395 Score = 443 bits (1140), Expect = e-125, Method: Composition-based stats. Identities = 132/397 (33%), Positives = 205/397 (51%), Gaps = 15/397 (3%) Query: 30 EKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVA 89 + ++VVIV+A R+ IG F G+ + L + I + P ++E Sbjct: 4 KPTLKEVVIVSATRTPIGS-FLGSLSLLPATKLGSIAIQGAIEKAGIPKE----EVKEAY 58 Query: 90 CGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLA 149 GNVL G G R A L +G+P STP +N+ C+SG+ A+ + + G D+ +A Sbjct: 59 MGNVLQGGEGQAPTRQAVLGAGLPISTPCTTINKVCASGMKAIMMASQSLMCGHQDVMVA 118 Query: 150 LGVESMTNNYKNVN----PLGMISSEEL--QKNREAKKCLIPMGITNENVAANFKISRKD 203 G+ESM+N +N P G + E+L + I MG EN A I+R + Sbjct: 119 GGMESMSNVPYVMNRGSTPYGGVKLEDLIVKDGLTDVYNKIHMGSCAENTAKKLNIARNE 178 Query: 204 QDEFAANSYQKAYKAKNEGLFEDEILPIKLP---DGSICQSDEGPRPNVTAESLSSIRPA 260 QD +A NSY ++ A G F +E++P+ + + ++ V + ++ Sbjct: 179 QDAYAINSYTRSKAAWEAGKFGNEVIPVTVTVKGQPDVVVKEDEEYKRVDFSKVPKLKTV 238 Query: 261 FIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPA 320 F K+ GT TA NAS ++DG A ++L A +LN+ L R + F V P + P Sbjct: 239 FQKENGTVTAANASTLNDGAAALVLMTADAAKRLNVTPLARIVAFADAAVEPIDFPIAPV 298 Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCT 380 YA VL+ GL+ +DI ++E+NEAF+ L I L ID KVN GGA++LGHP+G + Sbjct: 299 YAASMVLKDVGLKKEDIAMWEVNEAFSLVVLANIKMLEIDPQKVNINGGAVSLGHPIGMS 358 Query: 381 GARQVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE 417 GAR V + LK+ + G+ S+C G G GA+A+ I++ Sbjct: 359 GARIVGHLTHALKQGEYGLASICNGGG-GASAMLIQK 394 >3SS6-A nrPDB Length = 394 Score = 442 bits (1138), Expect = e-125, Method: Composition-based stats. Identities = 148/395 (37%), Positives = 222/395 (56%), Gaps = 19/395 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +VVI AA RS IG F GA K+V L L E + R + + ++EV G+ Sbjct: 5 HNVVITAAVRSPIGT-FGGALKNVTPVELAVPVLQEAVKRG----GVEPHEVDEVILGHC 59 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 + A R A LA+G P + + RQCSSG+ A+ A +I++G ++ +A GVE Sbjct: 60 IQRTDEANTARTAALAAGFPDTVTGYTIQRQCSSGMQAIMSAAMQIQLGVSEVVVAGGVE 119 Query: 154 SMTNNYKNVNPLGMISS-------EELQKNREAKKCLIPMGITNENVAANFKISRKDQDE 206 +M+++ + + + + E I MG T EN+ ++I+R++QDE Sbjct: 120 AMSSSPYALKQHRWGQRLQHGEIRDTVWEVLEDPIHHIMMGETAENLVEQYEITREEQDE 179 Query: 207 FAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIRPAFIK 263 A S+ A KA G F+D+I+PI + + + DE PR ++TAE L+ ++PAF K Sbjct: 180 VALRSHTLALKAIESGYFDDQIVPITIKERRKEVVFSKDEHPRADITAEKLAGLKPAFRK 239 Query: 264 DRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAI 323 D G+ TAGNAS ++DG A ++L A + L L R + + GV P+IMG+GPA AI Sbjct: 240 D-GSVTAGNASGLNDGSAVLVLMSEEKAKEKGLQPLARIVGYSVAGVDPKIMGIGPAPAI 298 Query: 324 PKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGAR 383 K LE ++D D+ EINEAFAAQ L +L +D KVN G + LGHP+GCTGAR Sbjct: 299 RKGLEKVDWSLEDADLLEINEAFAAQYLAVEKELDLDREKVNVNGSGVGLGHPIGCTGAR 358 Query: 384 QVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 +++ ELK+ + G+ S+C+G G+G A +FI+ Sbjct: 359 ITVSLIHELKRRGLEKGIASLCVGGGIGVA-LFIE 392 >1WDK-C nrPDB Length = 390 Score = 440 bits (1132), Expect = e-124, Method: Composition-based stats. Identities = 141/395 (35%), Positives = 205/395 (51%), Gaps = 18/395 (4%) Query: 32 RPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACG 91 P DVVIV R+ +G+ G ++ + + + +++ + R + D +E+V G Sbjct: 3 NPRDVVIVDFGRTPMGRSKGGMHRNTRAEDMSAHLISKVLERN---SKVDPGEVEDVIWG 59 Query: 92 NVLNV-GAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 V G R A L + IP+++ ++R C S ++A++ A I G D+ + Sbjct: 60 CVNQTLEQGWNIARMASLMTQIPHTSAAQTVSRLCGSSMSALHTAAQAIMTGNGDVFVVG 119 Query: 151 GVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAAN 210 GVE M + + + A K MG+T E + ISR+ QD FA Sbjct: 120 GVEHMGHVS-----MMHGVDPNPHMSLYAAKASGMMGLTAEMLGKMHGISREQQDAFAVR 174 Query: 211 SYQKAYKAKNEGLFEDEILPIKLPDG----SICQSDEGPRPNVTAESLSSIRPAFIKDRG 266 S+Q A+KA EG F+DEI+P++ D I DE RP+ T ESL++++PAF G Sbjct: 175 SHQLAHKATVEGKFKDEIIPMQGYDENGFLKIFDYDETIRPDTTLESLAALKPAFNPKGG 234 Query: 267 TTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKV 326 T TAG +SQ++DG + +++ A L L L GV P IMG GP A K Sbjct: 235 TVTAGTSSQITDGASCMIVMSAQRAKDLGLEPLAVIRSMAVAGVDPAIMGYGPVPATQKA 294 Query: 327 LEATGLQVQDIDIFEINEAFAAQALYCIHKLG-IDL--NKVNPRGGAIALGHPLGCTGAR 383 L+ GL + DID E+NEAFAAQAL + L +D KVN GGAIALGHP GC+GAR Sbjct: 295 LKRAGLNMADIDFIELNEAFAAQALPVLKDLKVLDKMNEKVNLHGGAIALGHPFGCSGAR 354 Query: 384 QVATILRELKK--DQIGVVSMCIGTGMGAAAIFIK 416 T+L +K+ G+ +MCIG G G A +F + Sbjct: 355 ISGTLLNVMKQNGGTFGLSTMCIGLGQGIATVFER 389 >2WUA-A nrPDB Length = 440 Score = 440 bits (1131), Expect = e-124, Method: Composition-based stats. Identities = 190/415 (45%), Positives = 255/415 (61%), Gaps = 25/415 (6%) Query: 16 AMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFP 75 A G + ++NS+ +DVVIVAA RS + K +G KD D +L L I + Sbjct: 18 AAGDSAAYQRNSVFG---DDVVIVAAYRSPLCKAKRGGLKDTYPDDILAPVLKALIEK-- 72 Query: 76 EPLRADLNLIEEVACGNVLNVGAG-ATEHRAACLASGIPYSTPFVALNRQCSSGLTAVND 134 + + ++ G+VL G+ A+E R A +G P + P +NRQCSSGL AV D Sbjct: 73 --TNINPAEVGDIVVGSVLGAGSQRASECRMAAFYAGFPETVPVRTVNRQCSSGLQAVAD 130 Query: 135 IANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVA 194 +A IK G DIG+ G+ESMT N + +++ +A+ CL+PMGIT+ENVA Sbjct: 131 VAAAIKAGFYDIGIGAGLESMTANPMAWEG---SVNPKVKTMAQAQDCLLPMGITSENVA 187 Query: 195 ANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP---------DGSICQSDEGP 245 F I+R++QD+ A S++K A G F+DEI+PIK D+G Sbjct: 188 QKFSITRQEQDQAAVGSHRKTAAATAAGRFKDEIIPIKTKIVDPKTGDEKPVTISVDDGI 247 Query: 246 RPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDF 305 RP + L+ ++P F KD G+TTAG +SQVSDG VLL +RS+A Q LP+LG + F Sbjct: 248 RPGTSLADLAKLKPVFRKD-GSTTAGTSSQVSDGAGAVLLMKRSIALQKGLPILGVFRTF 306 Query: 306 QTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVN 365 VGVPP IMG+GPA AIP ++A GLQ+ DID+FEINEAFA+Q +YC KL ID K+N Sbjct: 307 AAVGVPPSIMGIGPAVAIPAAVKAAGLQIDDIDLFEINEAFASQFVYCQKKLEIDPQKIN 366 Query: 366 PRGGAIALGHPLGCTGARQVATILRELKKD----QIGVVSMCIGTGMGAAAIFIK 416 GGA+A+GHPLG TGAR VAT+L E+K+ + GVVSMCIGTGMGAAA+F + Sbjct: 367 VNGGAMAIGHPLGATGARCVATLLHEMKRRGRDCRFGVVSMCIGTGMGAAAVFER 421 >6BN2-A nrPDB Length = 401 Score = 439 bits (1130), Expect = e-124, Method: Composition-based stats. Identities = 125/395 (31%), Positives = 205/395 (51%), Gaps = 18/395 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 ++V IV+A R+ +G F G+ V L + + + + + I++V GNV Sbjct: 10 KEVFIVSAVRTPMGS-FMGSLSGVPATQLGAVAIKGALDK----INLNPAEIQDVYMGNV 64 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G + A L +G+P +TP A+N+ C+SG+ AV A +K G ++ +A G+E Sbjct: 65 LQAGEGQAPAKQAALGAGLPNTTPTTAVNKVCASGMKAVMMAAQAVKAGDVEAIVAGGME 124 Query: 154 SMTNNYKNVNPLGMIS-------SEELQKNREAKKCLIPMGITNENVAANFKISRKDQDE 206 +M+ ++ + L+ MG E A + I+R++QD Sbjct: 125 NMSQVPHYIDGRNGVKLGDIKLQDGLLKDGLTDVYSKQHMGNCAELCAKEYNITREEQDA 184 Query: 207 FAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIRPAFIK 263 FA SY+++ KA +EG F++E++P+ +P I +++ NV + + ++ F K Sbjct: 185 FAIQSYERSAKAWSEGKFKEEVVPVSIPQRKGEPIIFAEDEEYKNVKFDRIPTLPTVFQK 244 Query: 264 DRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAI 323 + GT TA NAS ++DG + ++L + L L L + + + PE PA A+ Sbjct: 245 ENGTVTAANASTLNDGASALVLMSKEKMESLGLKPLAKIVSYADAAQAPEWFTTAPAKAL 304 Query: 324 PKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGAR 383 P L L + DID FE NEAF+ L LG+D KVN GGA+ALGHPLG +G+R Sbjct: 305 PIALAKANLTINDIDFFEFNEAFSVVGLANNKILGLDAAKVNVNGGAVALGHPLGSSGSR 364 Query: 384 QVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 + T++ LK++ + G ++C G G GA+AI I+ Sbjct: 365 IIVTLINVLKQNNAKYGAAAICNGGG-GASAIVIE 398 >2IIK-A nrPDB Length = 418 Score = 437 bits (1124), Expect = e-123, Method: Composition-based stats. Identities = 202/392 (51%), Positives = 253/392 (64%), Gaps = 19/392 (4%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94 DVV+V R+AI + +G FKD D LL + + + + ++ GNVL Sbjct: 31 DVVVVHGRRTAICRAGRGGFKDTTPDELLSAVMTAVLK----DVNLRPEQLGDICVGNVL 86 Query: 95 NVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 GAGA R A S IP + P +NRQCSSGL AV IA I+ G DIG+A GVES Sbjct: 87 QPGAGAIMARIAQFLSDIPETVPLSTVNRQCSSGLQAVASIAGGIRNGSYDIGMACGVES 146 Query: 155 MTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQK 214 M+ + G I+S ++K + A+ CLIPMGIT+ENVA F ISR+ QD FA S QK Sbjct: 147 MSLADRGNP--GNITSRLMEKEK-ARDCLIPMGITSENVAERFGISREKQDTFALASQQK 203 Query: 215 AYKAKNEGLFEDEILPIKL--------PDGSICQSDEGPRPNVTAESLSSIRPAFIKDRG 266 A +A+++G F+ EI+P+ DEG RP+ T E L+ ++PAF KD G Sbjct: 204 AARAQSKGCFQAEIVPVTTTVHDDKGTKRSITVTQDEGIRPSTTMEGLAKLKPAFKKD-G 262 Query: 267 TTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKV 326 +TTAGN+SQVSDG A +LLARRS A +L LP+LG + VGVPP+IMG+GPAYAIP Sbjct: 263 STTAGNSSQVSDGAAAILLARRSKAEELGLPILGVLRSYAVVGVPPDIMGIGPAYAIPVA 322 Query: 327 LEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVA 386 L+ GL V D+DIFEINEAFA+QA YC+ KL + KVNP GGA+ALGHPLGCTGARQV Sbjct: 323 LQKAGLTVSDVDIFEINEAFASQAAYCVEKLRLPPEKVNPLGGAVALGHPLGCTGARQVI 382 Query: 387 TILRELKKDQ---IGVVSMCIGTGMGAAAIFI 415 T+L ELK+ GVVSMCIGTGMGAAA+F Sbjct: 383 TLLNELKRRGKRAYGVVSMCIGTGMGAAAVFE 414 >1NL7-A nrPDB Length = 392 Score = 436 bits (1122), Expect = e-123, Method: Composition-based stats. Identities = 146/392 (37%), Positives = 209/392 (53%), Gaps = 18/392 (4%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 +VI +A R+A+G F GAF + L ++ + R + EV G VL Sbjct: 5 IVIASAARTAVGS-FNGAFANTPAHELGATVISAVLERA----GVAAGEVNEVILGQVLP 59 Query: 96 VGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESM 155 G G R A + +G+P +N+ C SGL AV +I G I +A G+ESM Sbjct: 60 AGEGQNPARQAAMKAGVPQEATAWGMNQLCGSGLRAVALGMQQIATGDASIIVAGGMESM 119 Query: 156 TNNYKNVNPLGMIS-------SEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFA 208 + + G + ++ MG T ENVA +++SR +QD FA Sbjct: 120 SMAPHCAHLRGGVKMGDFKMIDTMIKDGLTDAFYGYHMGTTAENVAKQWQLSRDEQDAFA 179 Query: 209 ANSYQKAYKAKNEGLFEDEILP--IKLPDGSI-CQSDEGPRPNVTAESLSSIRPAFIKDR 265 S KA A+ +G F+DEI+P +K G I +DE R T +S++ +RPAF K+ Sbjct: 180 VASQNKAEAAQKDGRFKDEIVPFIVKGRKGDITVDADEYIRHGATLDSMAKLRPAFDKE- 238 Query: 266 GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPK 325 GT TAGNAS ++DG A LL + A++ + LGR + + TVGV P++MG GP A K Sbjct: 239 GTVTAGNASGLNDGAAAALLMSEAEASRRGIQPLGRIVSWATVGVDPKVMGTGPIPASRK 298 Query: 326 VLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQV 385 LE G ++ D+D+ E NEAFAAQA LG D + VN GGAIA+GHP+G +GAR + Sbjct: 299 ALERAGWKIGDLDLVEANEAFAAQACAVNKDLGWDPSIVNVNGGAIAIGHPIGASGARIL 358 Query: 386 ATILRELKKD--QIGVVSMCIGTGMGAAAIFI 415 T+L E+K+ + G+ ++CIG GMG A Sbjct: 359 NTLLFEMKRRGARKGLATLCIGGGMGVAMCIE 390 >2C7Y-A nrPDB Length = 404 Score = 436 bits (1121), Expect = e-122, Method: Composition-based stats. Identities = 192/412 (46%), Positives = 257/412 (62%), Gaps = 25/412 (6%) Query: 19 KGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPL 78 + ++ SL +DVVIVAA+R+ + K +G FKD D LL L I + Sbjct: 1 DSAAYQRTSLYG---DDVVIVAAHRTPLCKSKRGNFKDTYPDDLLAPVLRALIEK----T 53 Query: 79 RADLNLIEEVACGNVLNVGAG-ATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIAN 137 + + + ++ G VL G+ A+E R A +G P + +NRQCSSGL AV D+A Sbjct: 54 NLNPSEVGDIVVGTVLAPGSQRASECRMAAFYAGFPETVAVRTVNRQCSSGLQAVADVAA 113 Query: 138 KIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANF 197 IK G DIG+ G+ESMT N + ++K +A+ CL+PMG+T+ENVA F Sbjct: 114 AIKAGFYDIGIGAGLESMTTNPMAWEG---SVNPAVKKFAQAQNCLLPMGVTSENVAQRF 170 Query: 198 KISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP---------DGSICQSDEGPRPN 248 +SR++QD+ A +S++KA A G F+DEI+P+K D+G RP Sbjct: 171 GVSRQEQDQAAVDSHRKAAAATAAGKFKDEIIPVKTKLVDPKTGDEKPITVSVDDGIRPT 230 Query: 249 VTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTV 308 T SL ++P F KD GTTTAGN+SQVSDG VLL +RSVA Q LPVLG + F V Sbjct: 231 TTLASLGKLKPVFKKD-GTTTAGNSSQVSDGAGAVLLMKRSVAMQKGLPVLGVFRTFAAV 289 Query: 309 GVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRG 368 GV P IMG+GPA AIP ++A GL++ DID+FEINEAFA+Q +YC +KLG+D K+N G Sbjct: 290 GVDPAIMGIGPAVAIPAAVKAAGLELDDIDLFEINEAFASQFVYCRNKLGLDPEKINVNG 349 Query: 369 GAIALGHPLGCTGARQVATILRELKKD----QIGVVSMCIGTGMGAAAIFIK 416 GA+A+GHPLG TGAR VAT+L E+K+ + GVVSMCIGTGMGAAA+F + Sbjct: 350 GAMAIGHPLGATGARCVATLLHEMKRRGKDCRFGVVSMCIGTGMGAAAVFER 401 >1ULQ-A nrPDB Length = 401 Score = 434 bits (1117), Expect = e-122, Method: Composition-based stats. Identities = 147/402 (36%), Positives = 206/402 (51%), Gaps = 27/402 (6%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94 + IV A R+ IGK GA V D LL + L+ + R P +E+V G Sbjct: 3 EAWIVEAVRTPIGK-HGGALASVRPDDLLAHALSVLVDRSGVPKE----EVEDVYAGCAN 57 Query: 95 NVGAGA-TEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 G R A L +G P +NR C SGL AV A I G+ + + GVE Sbjct: 58 QAGEDNRNVARMALLLAGFPVEVAGCTVNRLCGSGLEAVAQAARAIWAGEGKVYIGSGVE 117 Query: 154 SMTNNYKNVNP-------------LGMISSEELQKNREAKKCLIPMGITNENVAANFKIS 200 SM+ V + + +A MG T EN+A + I Sbjct: 118 SMSRAPYAVPKPERGFPTGNLVMYDTTLGWRFVNPKMQALYGTESMGETAENLAEMYGIR 177 Query: 201 RKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSI 257 R++QD FA S+QKA +A EG F+DE++P+ + G + + DEGPR + + E L+++ Sbjct: 178 REEQDRFALLSHQKAVRAWEEGRFQDEVVPVPVKRGKEEILVEQDEGPRRDTSLEKLAAL 237 Query: 258 RPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGV 317 RP F ++ GT TAGN+S ++DG A VLL A L L R GVPP IMG+ Sbjct: 238 RPVF-REGGTVTAGNSSPLNDGAAAVLLVSDDYAKAHGLRPLARVRAIAVAGVPPRIMGI 296 Query: 318 GPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLN--KVNPRGGAIALGH 375 GP A K LE GL D+ + E+NEAFAAQAL + + + + ++NP GGAIALGH Sbjct: 297 GPVPATRKALERAGLSFSDLGLIELNEAFAAQALAVLREWSLSMEDQRLNPNGGAIALGH 356 Query: 376 PLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFI 415 PLG +GAR + T++ E+++ Q G+ +MCIG G G A + Sbjct: 357 PLGASGARILTTLVHEMRRRKVQFGLATMCIGVGQGIAVVVE 398 >3GOA-A nrPDB Length = 387 Score = 433 bits (1114), Expect = e-122, Method: Composition-based stats. Identities = 150/393 (38%), Positives = 206/393 (52%), Gaps = 18/393 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 E VVIV A R+ +G+ GAF++V + L + + + R P A ++++ G V Sbjct: 2 EQVVIVDAIRTPMGRSKGGAFRNVRAEDLSAHLMRSLLARNPSLTAAT---LDDIYWGCV 58 Query: 94 LNV-GAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 G R A L + IP+S P V +NR C S + A++D A I G + L GV Sbjct: 59 QQTLEQGFNIARNAALLAEIPHSVPAVTVNRLCGSSMQALHDAARMIMTGDAQVCLVGGV 118 Query: 153 ESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSY 212 E M + P+ +R K MG+T E ++ ISR+ QD+FAA S+ Sbjct: 119 EHMGHV-----PMSHGVDFHPGLSRNVAKAAGMMGLTAEMLSRLHGISREMQDQFAARSH 173 Query: 213 QKAYKAKNEGLFEDEILPIKLPDGS----ICQSDEGPRPNVTAESLSSIRPAFIKDRGTT 268 +A+ A G F+ EI+P D DE RP T E+LS++RPAF GT Sbjct: 174 ARAWAATQSGAFKTEIIPTGGHDADGVLKQFNYDEVIRPETTVEALSTLRPAFDPVSGTV 233 Query: 269 TAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKVLE 328 TAG +S +SDG A +L+ S A +L L R VG P IMG GP A L+ Sbjct: 234 TAGTSSALSDGAAAMLVMSESRARELGLKPRARIRSMAVVGCDPSIMGYGPVPASKLALK 293 Query: 329 ATGLQVQDIDIFEINEAFAAQALYCIHKLGIDL---NKVNPRGGAIALGHPLGCTGARQV 385 GL DID+FE+NEAFAAQ L CI LG+ K+N GGAIALGHPLGC+GAR Sbjct: 294 KAGLSASDIDVFEMNEAFAAQILPCIKDLGLMEQIDEKINLNGGAIALGHPLGCSGARIS 353 Query: 386 ATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 T++ +++ Q G+ +MCIG G G A +F + Sbjct: 354 TTLINLMERKDAQFGLATMCIGLGQGIATVFER 386 >4O9A-A nrPDB Length = 398 Score = 425 bits (1094), Expect = e-119, Method: Composition-based stats. Identities = 144/398 (36%), Positives = 209/398 (52%), Gaps = 20/398 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 DVVIV+A R+A+GK F G+ + L + + R + EV G V Sbjct: 7 TDVVIVSAARTAVGK-FGGSLAKIPAPELGAVVIKAALERA----GVKPEQVSEVIMGQV 61 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G+G R A + +G+P P + +N+ SGL AV AN I G +I +A G E Sbjct: 62 LTAGSGQNPARQAAIKAGLPAMVPAMTINKVSGSGLKAVMLAANAIMAGDAEIVVAGGQE 121 Query: 154 SMTNNYKNVNP--------LGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQD 205 +M+ + + + MGIT ENVA + I+R+ QD Sbjct: 122 NMSAAPHVLPGSRDGFRMGDAKLVDTMIVDGLWDVYNQYHMGITAENVAKEYGITREAQD 181 Query: 206 EFAANSYQKAYKAKNEGLFEDEILPIKLP----DGSICQSDEGPRPNVTAESLSSIRPAF 261 EFA S KA A+ G F++EI+P+ +P D ++DE R T +S+S ++PAF Sbjct: 182 EFAVGSQNKAEAAQKAGKFDEEIVPVLIPQRKGDPVAFKTDEFVRQGATLDSMSGLKPAF 241 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 K GT TA NAS ++DG A V++ + A +L L L + GV P++MG+GP Sbjct: 242 DK-AGTVTAANASGLNDGAAAVVVMSAAKAKELGLTPLATIKSYANAGVDPKVMGMGPVP 300 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 A + L QD+D+ EINEAFAAQAL ++G D +KVN GGAIA+GHP+G +G Sbjct: 301 ASKRALSRAEWTPQDLDLMEINEAFAAQALAVHQQMGWDTSKVNVNGGAIAIGHPIGASG 360 Query: 382 ARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIKE 417 R + T+L E+K+ + G+ S+CIG GMG A ++ Sbjct: 361 CRILVTLLHEMKRRDAKKGLASLCIGGGMGVALAVERK 398 >4WYS-A nrPDB Length = 405 Score = 424 bits (1090), Expect = e-119, Method: Composition-based stats. Identities = 149/397 (37%), Positives = 210/397 (52%), Gaps = 20/397 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 ++ VIV+A R+AIG F G+ + L + I R + D ++EV GNV Sbjct: 5 KNCVIVSAVRTAIGS-FNGSLASTSAIDLGATVIKAAIERA----KIDSQHVDEVIMGNV 59 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L G G R A L SG+ + +N+ C SGL +V A I+ GQ +A G+E Sbjct: 60 LQAGLGQNPARQALLKSGLAETVCGFTVNKVCGSGLKSVALAAQAIQAGQAQSIVAGGME 119 Query: 154 SMTNNYKNVN---------PLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQ 204 +M+ ++ G + L+ MGIT ENVA + I+R+ Q Sbjct: 120 NMSLAPYLLDAKARSGYRLGDGQVYDVILRDGLMCATHGYHMGITAENVAKEYGITREMQ 179 Query: 205 DEFAANSYQKAYKAKNEGLFEDEILPIKL---PDGSICQSDEGPRPNVTAESLSSIRPAF 261 DE A +S +KA A G F EI+P+ + + DE P+ N TAE+L ++RPAF Sbjct: 180 DELALHSQRKAAAAIESGAFTAEIVPVNVVTRKKTFVFSQDEFPKANSTAEALGALRPAF 239 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 K GT TAGNAS ++DG A +++ S A L L R + + GVPP +MG+GP Sbjct: 240 DK-AGTVTAGNASGINDGAAALVIMEESAALAAGLTPLARIKSYASGGVPPALMGMGPVP 298 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 A K L+ GLQ+ DID+ E NEAFAAQ L LG D KVN GGAIALGHP+G +G Sbjct: 299 ATQKALQLAGLQLADIDLIEANEAFAAQFLAVGKNLGFDSEKVNVNGGAIALGHPIGASG 358 Query: 382 ARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 AR + T+L ++ +G+ ++CIG G G A + + Sbjct: 359 ARILVTLLHAMQARDKTLGLATLCIGGGQGIAMVIER 395 >4C2K-A nrPDB Length = 417 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 137/396 (34%), Positives = 195/396 (49%), Gaps = 20/396 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 V +VAA R+ G + G KD L + + ++ V GNV Sbjct: 25 RGVFVVAAKRTPFG-AYGGLLKDFTATDLSEFAAKAAL----SAGKVSPETVDSVIMGNV 79 Query: 94 LNVGAGATE-HRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 L + A R L GIP TP + +NR C SG ++ + +I V + ++ L G Sbjct: 80 LQSSSDAIYLARHVGLRVGIPKETPALTINRLCGSGFQSIVNGCQEICVKEAEVVLCGGT 139 Query: 153 ESMTNNYKNVN--------PLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQ 204 ESM+ V + + L + + +PM +T EN+A KISR++ Sbjct: 140 ESMSQAPYCVRNVRFGTKLGSDIKLEDSLWVSLTDQHVQLPMAMTAENLAVKHKISREEC 199 Query: 205 DEFAANSYQKAYKAKNEGLFEDEILPIKLP---DGSICQSDEGPRPNVTAESLSSIRPAF 261 D++A S Q+ A + G F DE+ PI++ Q DE RP T E L + P F Sbjct: 200 DKYALQSQQRWKAANDAGYFNDEMAPIEVKTKKGKQTMQVDEHARPQTTLEQLQKLPPVF 259 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 KD GT TAGNAS V+DG V++A + N L R + + G P IMG+GP Sbjct: 260 KKD-GTVTAGNASGVADGAGAVIIASEDAVKKHNFTPLARIVGYFVSGCDPSIMGIGPVP 318 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 AI L+ GL ++D+D+ E+NEAFA Q L L +D++K N GGAIALGHPLG +G Sbjct: 319 AISGALKKAGLSLKDMDLVEVNEAFAPQYLAVERSLDLDISKTNVNGGAIALGHPLGGSG 378 Query: 382 ARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFI 415 +R A ++ EL++ + V S CIG G G A I Sbjct: 379 SRITAHLVHELRRRGGKYAVGSACIGGGQGIAVIIQ 414 >4NZS-A nrPDB Length = 399 Score = 420 bits (1079), Expect = e-118, Method: Composition-based stats. Identities = 144/396 (36%), Positives = 207/396 (52%), Gaps = 18/396 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +VV+V+ R+AIG F G+ KDV L + E + R + + + V GNV Sbjct: 8 REVVVVSGVRTAIGT-FGGSLKDVAPAELGALVVREALARA----QVSGDDVGHVVFGNV 62 Query: 94 LNVG-AGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 + R A + G+ + P + +NR C SGL A+ A I +G D+ + G Sbjct: 63 IQTEPRDMYLGRVAAVNGGVTINAPALTVNRLCGSGLQAIVSAAQTILLGDTDVAIGGGA 122 Query: 153 ESMTNNY------KNVNPLGMISS-EELQKNREAKKCLIPMGITNENVAANFKISRKDQD 205 ESM+ + +G + + I MG+T ENVA + ISR QD Sbjct: 123 ESMSRAPYLAPAARWGARMGDAGLVDMMLGALHDPFHRIHMGVTAENVAKEYDISRAQQD 182 Query: 206 EFAANSYQKAYKAKNEGLFEDEILPI--KLPDGSIC-QSDEGPRPNVTAESLSSIRPAFI 262 E A S+++A A G F+D+I+P+ K G + +DE R + T + ++ +RP F+ Sbjct: 183 EAALESHRRASAAIKAGYFKDQIVPVVSKGRKGDVTFDTDEHVRHDATIDDMTKLRPVFV 242 Query: 263 KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYA 322 K+ GT TAGNAS ++D A V++ R+ A + L L R + + GV P+ MG+GP A Sbjct: 243 KENGTVTAGNASGLNDAAAAVVMMERAEAERRGLKPLARLVSYGHAGVDPKAMGIGPVPA 302 Query: 323 IPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 LE GLQV D+D+ E NEAFAAQA LG+D KVNP G I+LGHP+G TGA Sbjct: 303 TKIALERAGLQVSDLDVIEANEAFAAQACAVTKALGLDPAKVNPNGSGISLGHPIGATGA 362 Query: 383 RQVATILRELKK--DQIGVVSMCIGTGMGAAAIFIK 416 L EL + + +V+MCIG G G AAIF + Sbjct: 363 LITVKALHELNRVQGRYALVTMCIGGGQGIAAIFER 398 >3SVK-A nrPDB Length = 407 Score = 417 bits (1072), Expect = e-117, Method: Composition-based stats. Identities = 142/411 (34%), Positives = 200/411 (48%), Gaps = 31/411 (7%) Query: 30 EKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVA 89 E+ I A R+ GK G+ +V L+ ++E R+P+ D LI ++ Sbjct: 3 GSMSEEAFIYEAIRTPRGKQKNGSLTEVKPLNLVVGLVDELRRRYPD---LDETLISDMI 59 Query: 90 CGNVLNVG-AGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGL 148 G V VG G R A LA+G+P +T V LNR C+SGL AVN A K++ G D+ L Sbjct: 60 LGVVSPVGDQGGDIARTAVLAAGLPETTGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVL 119 Query: 149 ALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFA 208 A GVESM+ + + E + +P GI + +A SR+D D +A Sbjct: 120 AGGVESMSRVPMGSDGGAWATDPE----TNYRIGFVPQGIGADLIATLEGFSREDVDAYA 175 Query: 209 ANSYQKAYKAKNEGLFEDEILPIKLPDG-SICQSDEGPRPNVTAESLSSIRPAFI----- 262 S QKA A + G F ++P++ +G I DE RP+ T E L+ ++ AF Sbjct: 176 LRSQQKAAAAWSGGYFAKSVVPVRDQNGLVILDHDEHMRPDTTMEGLAKLKTAFDGVGEM 235 Query: 263 ---------------KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQT 307 K T GN+S + DG A VL+ L R + T Sbjct: 236 GGFDDVALQKYHWVEKINHVHTGGNSSGIVDGAALVLVGSEKAGKSQGLTPRARIVATAT 295 Query: 308 VGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPR 367 G P IM GP A KVL+ GL + DID+FE+NEAFA+ L L I K+N Sbjct: 296 SGSDPVIMLTGPTPATRKVLDRAGLTIDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVN 355 Query: 368 GGAIALGHPLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 GGAIA+GHPLG TGA T++ EL++ + ++++CIG GMG A I + Sbjct: 356 GGAIAMGHPLGATGAMITGTMVDELERRNARRALITLCIGGGMGVATIIER 406 >5CBQ-A nrPDB Length = 413 Score = 411 bits (1057), Expect = e-115, Method: Composition-based stats. Identities = 130/405 (32%), Positives = 202/405 (49%), Gaps = 27/405 (6%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 D VI R+ IG+ + G F+ + L L + R + +E+V G+ Sbjct: 10 RDAVICEPVRTPIGR-YGGMFRSLTAVDLGVTALKGLLER----TGIAADQVEDVILGHC 64 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 R L +G+P + P + ++R+C SGL AV +++ G D+ +A G E Sbjct: 65 YPNSEAPAIGRVVALDAGLPITVPGMQVDRRCGSGLQAVIQACLQVRSGDHDLVVAGGAE 124 Query: 154 SMTNNYK-------NVNPLGMISSEELQKNREAKKCLIP-----MGITNENVAANFKISR 201 SM+N G+ + L + R M T EN+ + ISR Sbjct: 125 SMSNVAFYSTDMRWGGARTGVQIHDGLARGRTTAGGKFHPVPGGMLETAENLRREYHISR 184 Query: 202 KDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGS---ICQSDEGPRPNVTAESLSSIR 258 +QDE A S+Q+A A++EG+ +EI+P+ + DE PR + T E+L+ ++ Sbjct: 185 TEQDELAVRSHQRAVAAQSEGVLAEEIIPVPVRTRDGEETISVDEHPRADTTVEALAKLK 244 Query: 259 PAFIKD--RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMG 316 P +K T TAGN+S +D + ++ A +L L L R + + + GV P++MG Sbjct: 245 PVLLKQDPEATVTAGNSSGQNDAASMCIVTTPEKAAELGLKPLVRLVSWGSAGVAPDLMG 304 Query: 317 VGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGI---DLNKVNPRGGAIAL 373 +GP A L GL + DID+ E+NEAFAAQAL + + D + N RG I+L Sbjct: 305 IGPVPATEVALAKAGLTLADIDLIELNEAFAAQALAVMREWKFGEADHERTNVRGSGISL 364 Query: 374 GHPLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 GHP+G TG R +AT+ REL + + G+ +MCIG G G AA+F + Sbjct: 365 GHPVGATGGRMLATLARELHRREARYGLETMCIGGGQGLAAVFER 409 >6ARG-A nrPDB Length = 399 Score = 411 bits (1056), Expect = e-115, Method: Composition-based stats. Identities = 131/395 (33%), Positives = 200/395 (50%), Gaps = 19/395 (4%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 V IV++ R+ +G F G+ + L + + + + + ++EV GNV++ Sbjct: 8 VYIVSSARTPVGS-FLGSLSSLTAPQLGAHAIKAALAKVD---GLKPSDVQEVFFGNVIS 63 Query: 96 VGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESM 155 G R L +G+ ST +N+ C+SGL A+ A I G D+ +A G ESM Sbjct: 64 ANVGQNPARQCALGAGLEESTICTTVNKVCASGLKAIILGAQTIMTGNADVVVAGGTESM 123 Query: 156 TNNYKN------VNPLGMIS--SEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF 207 +N G S ++ MG+ E A + SR+ QDE+ Sbjct: 124 SNAPHYLPNLRTGAKYGHQSLVDGIMKDGLTDAGKQELMGLQAEECAQDHGFSREQQDEY 183 Query: 208 AANSYQKAYKAKNEGLFEDEILPIKLP----DGSICQSDEGPRPNVTAESLSSIRPAFIK 263 A +Y+KA A+ GLF++EI PI+LP + + + N+ E L +I+PAFI Sbjct: 184 AIRTYEKAQAAQKAGLFDEEIAPIQLPGFRGKPDVTVTQDEEPKNLNPEKLRAIKPAFIP 243 Query: 264 DRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAI 323 GT TA N+S ++DG A V+L + +LNL + + + + P PA AI Sbjct: 244 GSGTVTAPNSSPLNDGAAAVVLVSEAKLKELNLKPVAKILGWGDAAQQPSKFTTAPALAI 303 Query: 324 PKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGAR 383 PK L+ G+ ID FEINEAF+ AL + LGI KVN GGA+A+GHP+G +GAR Sbjct: 304 PKALKHAGVGQDAIDAFEINEAFSVVALANMKLLGIPEEKVNLHGGAVAIGHPIGASGAR 363 Query: 384 QVATILREL--KKDQIGVVSMCIGTGMGAAAIFIK 416 + T+L L KK ++G +C G G GA+A+ ++ Sbjct: 364 ILTTLLGVLKAKKGKLGCAGICNGGG-GASALVVE 397 >4B3J-C nrPDB Length = 403 Score = 410 bits (1055), Expect = e-115, Method: Composition-based stats. Identities = 145/407 (35%), Positives = 203/407 (49%), Gaps = 31/407 (7%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 E+ I A R+ GK G+ +V L+ ++E R P+ D NLI +V G V Sbjct: 3 EEAFIYEAIRTPRGKQKNGSLHEVKPLSLVVGLIDELRKRHPD---LDENLISDVILGCV 59 Query: 94 LNVG-AGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 VG G RAA LASG+P ++ V LNR C+SGL AVN A K++ G D+ LA GV Sbjct: 60 SPVGDQGGDIARAAVLASGMPVTSGGVQLNRFCASGLEAVNTAAQKVRSGWDDLVLAGGV 119 Query: 153 ESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSY 212 ESM+ + + L +P I + +A SR+D D +A S Sbjct: 120 ESMSRVPMGSDG----GAMGLDPATNYDVMFVPQSIGADLIATIEGFSREDVDAYALRSQ 175 Query: 213 QKAYKAKNEGLFEDEILPIKLPDGS-ICQSDEGPRPNVTAESLSSIRPAFI--------- 262 QKA +A + G F ++P++ +G I DE RP+ T E L+ ++PAF Sbjct: 176 QKAAEAWSGGYFAKSVVPVRDQNGLLILDHDEHMRPDTTKEGLAKLKPAFEGLAALGGFD 235 Query: 263 -----------KDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVP 311 K T GN+S + DG A V++ + L R + T G Sbjct: 236 DVALQKYHWVEKINHVHTGGNSSGIVDGAALVMIGSAAAGKLQGLTPRARIVATATSGAD 295 Query: 312 PEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAI 371 P IM GP A KVL+ GL V DID+FE+NEAFA+ L L I K+N GGAI Sbjct: 296 PVIMLTGPTPATRKVLDRAGLTVDDIDLFELNEAFASVVLKFQKDLNIPDEKLNVNGGAI 355 Query: 372 ALGHPLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFIK 416 A+GHPLG TGA + T++ EL++ + ++++CIG GMG A I + Sbjct: 356 AMGHPLGATGAMILGTMVDELERRNARRALITLCIGGGMGVATIIER 402 >5XYJ-B nrPDB Length = 408 Score = 408 bits (1048), Expect = e-114, Method: Composition-based stats. Identities = 135/405 (33%), Positives = 206/405 (50%), Gaps = 23/405 (5%) Query: 30 EKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVA 89 ++V IV+ R+ IG F+G+ L L + + PE +E+ Sbjct: 9 GSMSQNVYIVSTARTPIGS-FQGSLSSKTAVELGAVALKGALAKVPELDA--SKDFDEII 65 Query: 90 CGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLA 149 GNVL+ G R LA+G+ +N+ +S + A+ A IK G D+ +A Sbjct: 66 FGNVLSANLGQAPARQVALAAGLSNHIVASTVNKVAASAMKAIILGAQSIKCGNADVVVA 125 Query: 150 LGVESMTNNYKNV--NPLGMISSEELQKNREAKKCL------IPMGITNENVAANFKISR 201 G ESMTN + G + + + + L + MG+ E A ++ I+R Sbjct: 126 GGCESMTNAPYYMPAARAGAKFGQTVLVDGVERDGLNDAYDGLAMGVHAEKCARDWDITR 185 Query: 202 KDQDEFAANSYQKAYKAKNEGLFEDEILPIKL------PDGSICQSDEGPRPNVTAESLS 255 + QD FA SYQK+ K++ EG F++EI+P+ + PD + + +E R +V E L Sbjct: 186 EQQDNFAIESYQKSQKSQKEGKFDNEIVPVTIKGFRGKPDTQVTKDEEPARLHV--EKLR 243 Query: 256 SIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIM 315 S R F K+ GT TA NAS ++DG A V+L V + NL L + P Sbjct: 244 SARTVFQKENGTVTAANASPINDGAAAVILVSEKVLKEKNLKPLAIIKGWGEAAHQPADF 303 Query: 316 GVGPAYAIPKVLEATGLQ-VQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALG 374 P+ A+PK L+ G++ + +D FE NEAF+ L L +D +KVN GGA+ALG Sbjct: 304 TWAPSLAVPKALKHAGIEDINSVDYFEFNEAFSVVGLVNTKILKLDPSKVNVYGGAVALG 363 Query: 375 HPLGCTGARQVATILRELKK--DQIGVVSMCIGTGMGAAAIFIKE 417 HPLGC+GAR V T+L L++ +IGV ++C G G GA++I I++ Sbjct: 364 HPLGCSGARVVVTLLSILQQEGGKIGVAAICNGGG-GASSIVIEK 407 >6BJA-A nrPDB Length = 397 Score = 407 bits (1046), Expect = e-114, Method: Composition-based stats. Identities = 139/394 (35%), Positives = 207/394 (52%), Gaps = 16/394 (4%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 +DV I++A R+ I F+ ++ L E I R P A IEE GNV Sbjct: 9 KDVYILSAVRTPIAS-FRSTLTSLSAVDLGIVVTKEAIKRSLLPSSA----IEETIVGNV 63 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 L+ G G R +AS IP S+ V +N+ CSS + A+ A I+VG I +ALG E Sbjct: 64 LSAGLGQNIARQISIASEIPKSSQCVTINKVCSSSMKAIIMGAQAIQVGYRRIVVALGSE 123 Query: 154 SMTNNYKNVN----PLGMIS--SEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEF 207 SM+N V P G + + PMG+ E ++ +R+ D + Sbjct: 124 SMSNAPFYVPRGEIPFGGVQLVDALQRDGLMDSIEYQPMGLCAEKTVKDYAFTREQLDAY 183 Query: 208 AANSYQKAYKAKNEGLFEDEILPIKLPDG---SICQSDEGPRPNVTAESLSSIRPAFIKD 264 A SY+KA A EG F E++P+ +P + +++ + E + ++ PAF+KD Sbjct: 184 AIESYRKAEHAWKEGAFNKEVVPVSVPQKRGSKVVLTEDEEYKRLIPEKVPALHPAFLKD 243 Query: 265 R-GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAI 323 GT TA NAS ++DG A +LA V + L + + + + GV P V PA A+ Sbjct: 244 GSGTITAANASTINDGAAACVLASGEVVQEGRLKPIAKVLSYAEAGVEPIDFTVAPALAV 303 Query: 324 PKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGAR 383 ++L +GL + I ++EINEAF+ L I +L +D +VN RGGA+ALGHPLG +GAR Sbjct: 304 KQLLSQSGLDEESIALWEINEAFSVTGLAFIKELRLDPKRVNVRGGAVALGHPLGASGAR 363 Query: 384 QVATILRELKKDQIGVVSMCIGTGMGAAAIFIKE 417 V T++ LK D++GV ++C G G A+AI IK+ Sbjct: 364 IVVTLVHALKSDELGVAAICNGGGE-ASAILIKK 396 >5LP7-H nrPDB Length = 393 Score = 404 bits (1038), Expect = e-113, Method: Composition-based stats. Identities = 136/396 (34%), Positives = 201/396 (50%), Gaps = 20/396 (5%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 VIV+A R+ GK F G K+V L + E + + + +E G V Sbjct: 2 RKTVIVSAARTPFGK-FGGVLKEVKAAELGGIVMKEAL----QQAGVSGDDVEGNVMGMV 56 Query: 94 LNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 + G+G R A +G+P+S P LN+ C+SGL AV I+ DI +A G+E Sbjct: 57 VQAGSGQIPSRQAARLAGMPWSVPSETLNKVCASGLRAVTLCDQMIRAQDADILVAGGME 116 Query: 154 SMTNNYKNVN--------PLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQD 205 SM+N V G + + + M + A + ISR++QD Sbjct: 117 SMSNIPYAVPAGRWGARMGDGELRDLMVYDGLTCAFDEVHMAVHGNTAAKEYAISRREQD 176 Query: 206 EFAANSYQKAYKAKNEGLFEDEILPIKL----PDGSICQSDEGPRPNVTAESLSSIRPAF 261 E+A S+ +A KA +EG F+DEI+P+ ++ DE R + + + L+ + P + Sbjct: 177 EWALRSHARAAKAADEGKFQDEIVPVNWIGRKGKPNVVDKDEAIRRDTSLDQLAKLAPIY 236 Query: 262 IKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAY 321 D G+ TAGNA V+DG +L A +L L + F T G+P + P + Sbjct: 237 ASD-GSITAGNAPGVNDGAGAFVLMSEEKAAELGKRPLATILGFSTTGMPAHELAAAPGF 295 Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 AI K+L+ GL VQDID+FE+NEAFA+ L C +G DL KVN GGAIALGHP+G +G Sbjct: 296 AINKLLKKNGLTVQDIDLFEVNEAFASVVLTCEKIVGFDLEKVNVNGGAIALGHPIGASG 355 Query: 382 ARQVATILRELKKD--QIGVVSMCIGTGMGAAAIFI 415 AR + T++ ELK+ +GV ++C G G A + Sbjct: 356 ARILMTLVYELKRRGGGLGVAAICSGAAQGDAVLVQ 391 >6BJB-A nrPDB Length = 393 Score = 395 bits (1015), Expect = e-110, Method: Composition-based stats. Identities = 130/392 (33%), Positives = 200/392 (51%), Gaps = 14/392 (3%) Query: 33 PEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGN 92 DVV V A R+ IG F+ AF +V L L + +L++E G Sbjct: 7 ITDVVFVGAARTPIGS-FRSAFNNVPVTVLGREALKGALK----NANVKPSLVQEAFIGV 61 Query: 93 VLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 V+ AG R L +G ST A+N+ +SG+ A+ A+ +++ ++ +A G+ Sbjct: 62 VVPSNAGQGPARQVVLGAGCDVSTVVTAVNKMSASGMKAIACAASILQLDLQEMVVAGGM 121 Query: 153 ESMTNNYKNVN----PLGMIS--SEELQKNREAKKCLIPMGITNENVAANFKISRKDQDE 206 ESM+ + P G + I MG + VA F I+R++QD+ Sbjct: 122 ESMSCVPFYLPRGEIPFGGTKLIDGIPRDGLNDVYNDILMGACADKVAKQFAITREEQDK 181 Query: 207 FAANSYQKAYKAKNEGLFEDEILPIKLPDGS--ICQSDEGPRPNVTAESLSSIRPAFIKD 264 +A SY+++ A EG+F EI+P+++ G I ++ V E + ++PAF + Sbjct: 182 YAILSYKRSAAAWKEGIFAKEIIPLEVTQGKKTITVEEDEEYKKVNFEKIPKLKPAFTSE 241 Query: 265 RGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIP 324 G+ TA NAS ++DG A V++ A + L L R + + P G+ PA IP Sbjct: 242 -GSVTAANASTLNDGAAMVVMTTVDGAKKHGLKPLARMLAYGDAATHPIDFGIAPASVIP 300 Query: 325 KVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQ 384 KVL+ GLQ++DID++EINEAFA LY + LG+D +KVN GGA++LGHP+G +GAR Sbjct: 301 KVLKLAGLQIKDIDLWEINEAFAVVPLYTMKTLGLDESKVNIHGGAVSLGHPIGMSGARI 360 Query: 385 VATILRELKKDQIGVVSMCIGTGMGAAAIFIK 416 V ++ LK Q G ++C G G I K Sbjct: 361 VGHLVHTLKPGQKGCAAICNGGGGAGGMIIEK 392 >5ZQZ-B nrPDB Length = 474 Score = 391 bits (1004), Expect = e-109, Method: Composition-based stats. Identities = 132/445 (29%), Positives = 194/445 (43%), Gaps = 53/445 (11%) Query: 16 AMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFP 75 A ++K K +L + +VV+V R+ ++KD+ L L + R Sbjct: 34 AAPAVQTKTKKTLAKPNIRNVVVVDGVRTPFLLS-GTSYKDLMPHDLARAALTGLLHRTS 92 Query: 76 EPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDI 135 P ++ + G V+ + R A L +G TP + C S A+ Sbjct: 93 VPKEV----VDYIIFGTVIQEVKTSNVAREAALGAGFSDKTPAHTVTMACISANQAMTTG 148 Query: 136 ANKIKVGQIDIGLALGVESMTNNYKN------------------VNPLGMIS-------S 170 I GQ D+ +A GVE M++ L +IS + Sbjct: 149 VGLIASGQCDVIVAGGVELMSDVPIRHSRKMRKLMLDLNKAKSMGQRLSLISKFRFNFLA 208 Query: 171 EELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILP 230 EL E MG + + +AA F +SR +QDE+A S+ A KA++EGL D ++P Sbjct: 209 PELPAVSEFSTSET-MGHSADRLAAAFAVSRLEQDEYALRSHSLAKKAQDEGLLSD-VVP 266 Query: 231 IKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSV 290 K+P D G RP + E ++ ++PAFIK GT TA N+S ++DG + +L+ Sbjct: 267 FKVPGKDTVTKDNGIRP-SSLEQMAKLKPAFIKPYGTVTAANSSFLTDGASAMLIMAEEK 325 Query: 291 ANQLNLPVLGRYIDFQTVGVPPEI-MGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQ 349 A + DF V P+ + +GP YA PKVLE GL + DID FE +EAF+ Q Sbjct: 326 ALAMGYKPKAYLRDFMYVSQDPKDQLLLGPTYATPKVLEKAGLTMNDIDAFEFHEAFSGQ 385 Query: 350 ALYCIHKLGID-----------------LNKVNPRGGAIALGHPLGCTGARQVATILREL 392 L + D L K N GG+++LGHP G TG R V L Sbjct: 386 ILANFKAMDSDWFAENYMGRKTKVGLPPLEKFNNWGGSLSLGHPFGATGCRLVMAAANRL 445 Query: 393 KK--DQIGVVSMCIGTGMGAAAIFI 415 +K Q G+V+ C G G A I Sbjct: 446 RKEGGQYGLVAACAAGGQGHAMIVE 470 >4UBW-A nrPDB Length = 399 Score = 376 bits (965), Expect = e-104, Method: Composition-based stats. Identities = 128/393 (32%), Positives = 184/393 (46%), Gaps = 20/393 (5%) Query: 37 VIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNV 96 VIV A RS IGK G ++ LL + + +E+V G V Sbjct: 13 VIVEATRSPIGK-RNGWLSGLHATELLGAVQKAVVDKAGIQSGLHAGDVEQVIGGCVTQF 71 Query: 97 GAGAT-EHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESM 155 G + R A L +G+P ++ QC SG A + IA I G ID+G+A G+E+M Sbjct: 72 GEQSNNISRVAWLTAGLPEHVGATTVDCQCGSGQQANHLIAGLIAAGAIDVGIACGIEAM 131 Query: 156 TNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKA 215 + N L + + L E +A I+R+D D F S ++A Sbjct: 132 SRVGLGANA---GPDRSLIRAQSWDIDLPNQFEAAERIAKRRGITREDVDVFGLESQRRA 188 Query: 216 YKAKNEGLFEDEILPIKLP----------DGSICQSDEGPRPNVTAESLSSIRPAFIKDR 265 +A EG F+ EI PI+ P + + D+G R T L ++P + Sbjct: 189 QRAWAEGRFDREISPIQAPVLDEQNQPTGERRLVFRDQGLR-ETTMAGLGELKPVL--EG 245 Query: 266 GTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPK 325 G TAG +SQ+SDG A VL +VA L R + VG P GP + K Sbjct: 246 GIHTAGTSSQISDGAAAVLWMDEAVARAHGLTPRARIVAQALVGAEPYYHLDGPVQSTAK 305 Query: 326 VLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQV 385 VLE G+++ DIDI EINEAFA+ L D+++VN GGAIALGHP+GCTG+R + Sbjct: 306 VLEKAGMKIGDIDIVEINEAFASVVLSWARVHEPDMDRVNVNGGAIALGHPVGCTGSRLI 365 Query: 386 ATILRELKK--DQIGVVSMCIGTGMGAAAIFIK 416 T L EL++ + +++MC G + I + Sbjct: 366 TTALHELERTDQSLALITMCAGGALSTGTIIER 398 >5LNQ-A nrPDB Length = 457 Score = 235 bits (600), Expect = 2e-62, Method: Composition-based stats. Identities = 90/433 (20%), Positives = 152/433 (35%), Gaps = 81/433 (18%) Query: 36 VVIVAANRSAI-GKGFK----------GAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNL 84 V IV + + GKG G K++ + +L + + R + Sbjct: 31 VFIVGGHITPFVGKGSPLFIDKKHPDFGKKKNMTLEEILATTVQGTMEHSGLSGR--EGI 88 Query: 85 IEEVACGNVL---NVGAGA-TEHRAACLASGIPYST------PFVALNRQCSSGLTAVND 134 +++V GN L G L G S P + + +SG AV Sbjct: 89 VDQVVVGNFLGELFSSQGHLGPAAIGSLTYGQAGSKNPLMYKPAMRVEGAAASGGLAVIS 148 Query: 135 IANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITN--EN 192 N +K G DI LA+GVE T V + + + Q+ R+ P + Sbjct: 149 AMNALKSGSADITLAVGVEVQTTASARVGGDYLARAADYQRQRQLDDFTFPCLFAKRMKY 208 Query: 193 VAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAE 252 +A + + +D AA +Y K + ++ T E Sbjct: 209 IAEHNHFTMEDTARVAAKAYANGNKNPLAHMHTRKL---------------------TFE 247 Query: 253 SLSSIRPAFIKDRGTTT------AGNASQVSDGVAGVLLARRSVANQLNLPV-LGRYIDF 305 + P+ +K G T + SQVSDG AGV+LA ++ L R ++ Sbjct: 248 QCNGEDPSNVKFLGNETYKEYLRMTDCSQVSDGGAGVVLANEEGLRKMGLSPNDSRLVEI 307 Query: 306 QTVGVPPEIMGVGP---------AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHK 356 +++ + P A K L ++ D+++ E+++ F + Sbjct: 308 KSIACAVSNLYEDPDDACCMFTSRQAAQKALSMANIKPSDLNVAEVHDCFTIAEMLMYEA 367 Query: 357 LGIDLN------------------KVNPRGGAIALGHPLGCTGARQVATILRELKKDQIG 398 LGI VN GG ++ GHP+G TG +Q+ + R++K Q Sbjct: 368 LGIAEYGHAKDLIRNGDTTLEGRIPVNTGGGLLSFGHPVGATGIKQIMEVYRQMK-GQCE 426 Query: 399 VVSMCIGTGMGAA 411 M +GA Sbjct: 427 AYQMKKIPALGAT 439 >6ESQ-A nrPDB Length = 392 Score = 226 bits (576), Expect = 1e-59, Method: Composition-based stats. Identities = 88/424 (20%), Positives = 156/424 (36%), Gaps = 98/424 (23%) Query: 34 EDVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNV 93 DV I+ ++ G+ ++ +F+D+ + E + + D I+ + GN+ Sbjct: 2 RDVAIIGYGQTKFGELWEDSFRDL---------IVEAGVKAIKDANVDGGDIDAMYIGNM 52 Query: 94 LNVGAGATEHRAACLASGIPYS-TPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV 152 EH A+ +A + P + C+SG A+ + G D+ LA GV Sbjct: 53 SGGLFVGQEHIASLIADHAGLNPVPCTRVEAACASGSLALRSAVLSVASGHHDVVLAGGV 112 Query: 153 ESMTNNYKNVNPLGMISSEELQK----------NREAKKCLIPMGITNENVAANFKISRK 202 E MT+ + S +E + A++ + G+T E ++ I+ + Sbjct: 113 EKMTDVEDATAAIASASDQEWEAFFGATFPSLYAMMARRYMYQYGLTIEELSMWSVIAHE 172 Query: 203 DQDEFAANSY-QKAYKAKNEGLFEDEIL--PIK------LPDGS----ICQSDEGPRPNV 249 + + N Y Q +K E + + P+ + DG+ +C +D+ Sbjct: 173 NATK---NKYAQFGFKTTLEQVMNASPVADPLTLMHCSPVSDGASALIVCDADKAEEFAP 229 Query: 250 TAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG 309 E + +IK ++Q SD +A L R LN + ++ Sbjct: 230 KDEII------YIK--------ASTQASDTIA---LHDREDMTTLNAAKVASEKAYKLAK 272 Query: 310 VPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGI---------- 359 + P + ID+ E+++ FA L + LG Sbjct: 273 IAP----------------------EKIDVAEVHDCFAINGLILVEDLGFCKKGDAGKVI 310 Query: 360 ----------DLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIG---VVSMCIGT 406 D VNP GG A GH LG TG RQV + +LK+D+ ++ G Sbjct: 311 DEGKIRIDYDDFVTVNPSGGLKAAGHALGATGIRQVGELYWQLKQDKECKDRQATIKNGY 370 Query: 407 GMGA 410 G+ A Sbjct: 371 GIAA 374 >4BI9-A nrPDB Length = 454 Score = 211 bits (538), Expect = 4e-55, Method: Composition-based stats. Identities = 83/399 (20%), Positives = 142/399 (35%), Gaps = 58/399 (14%) Query: 52 GAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL---NVGAGA-TEHRAAC 107 G ++ + LL +N + L++++ GN L G Sbjct: 57 GKKENKTLEELLAESINGALQNTG-LHDGRAALVDKLVVGNFLGELFSSQGHLGPAAVGS 115 Query: 108 L---ASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 L S + P V + C+SG AV + G I LA+GVE T V Sbjct: 116 LSGSNSSAFLNKPAVRVEGACASGGLAVQSAWEALLAGTSQIALAVGVEVQTTVSARVGG 175 Query: 165 LGMISSEELQKNREAKKCLIPM----GITNENVAANFKISRKDQDEFAANSYQKAYKAKN 220 + + ++ R+ P + A +F + +D AA +Y + Sbjct: 176 DYLARAAHYKRQRQLDDFTFPCLFARRMKAIQEAGHF--TMEDAAYVAAKAYASGNRNPL 233 Query: 221 EGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGV 280 + ++ C PN + I F++ + SQVSDG Sbjct: 234 AHMHARKV------TLDFCTQASDKNPNFLG---NEIYKPFLR------TTDCSQVSDGG 278 Query: 281 AGVLLARRSVANQLNLPV-LGRYIDFQTVGVP--------PEIMGVGPAY-AIPKVLEAT 330 A V+LA +L L R ++ +++ P++ + + A L Sbjct: 279 AAVILASEEGLQKLGLSPNDNRLVEIKSLASAAGNLYEDSPDLTRMTTSMVAARTALSMA 338 Query: 331 GLQVQDIDIFEINEAFAAQALYCIHKLGIDLN------------------KVNPRGGAIA 372 G++ + + + E+++ F L LGI VN GG ++ Sbjct: 339 GVKPEQLQVAEVHDCFTIAELLMYEALGIAEYGGAGALIRSGATALDGRIPVNTGGGLLS 398 Query: 373 LGHPLGCTGARQVATILRELKKDQIGVVSMCIGTGMGAA 411 GHP+G TG +QV + R++K Q G M G+GA Sbjct: 399 FGHPVGATGVKQVLEVYRQMK-GQCGEYQMKNIPGIGAT 436 >6HRV-A nrPDB Length = 421 Score = 148 bits (374), Expect = 4e-36, Method: Composition-based stats. Identities = 79/396 (19%), Positives = 129/396 (32%), Gaps = 71/396 (17%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 V ++ + K +D++ + E R + I++ G V Sbjct: 16 VFVIGVGMTKFEKP---GARDIDYPDMA----KEAGQRALADAGIKYSAIQQACVGYVYG 68 Query: 96 VGAGATEHRAACLA-SGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 L SGIP + +N CS+G TA+ I+ G D LALG E Sbjct: 69 DSTCGQRAIYHSLGLSGIPI----INVNNNCSTGSTALFMGRQLIQGGLADCVLALGFEK 124 Query: 155 MTNNYKNVNPLGMISSEELQKNREAKKCLIPM----GITNENVA-ANFKIS-RKDQDEFA 208 M G +SS+ + + K + M G+ A F + R+ +++ Sbjct: 125 MER--------GSLSSKYMDRTNPMDKHMEVMINRYGLAAVPAAPQMFGNAGREHMEKYG 176 Query: 209 ANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTT 268 A A + DE + E + R F Sbjct: 177 TKPEHFAKVAWKNHKH-------STNNPYSQFQDEY-----SLEQVIDSRKVFE----FL 220 Query: 269 TAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYI-----------DFQTVGVPPEIMGV 317 T SDG +LA S + L I F+ + Sbjct: 221 TLLQCCPTSDGAGAAVLASESFVRRNGLEKKAVEIVAQEMVTDLSTTFEENSCMKMVGYD 280 Query: 318 GPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNK-------------- 363 A + + G++ D+D+ E+++ F+A L LG+ Sbjct: 281 MTRLAAERCYDTAGVKPSDVDVIELHDCFSANELITYEALGLCPEGKAGELIDRGDNTYG 340 Query: 364 ----VNPRGGAIALGHPLGCTGARQVATILRELKKD 395 +NP GG I+ GHPLG TG Q A + +L+ + Sbjct: 341 GKWVINPSGGLISKGHPLGATGLAQCAELCWQLRAE 376 >4YZO-A nrPDB Length = 373 Score = 105 bits (261), Expect = 4e-23, Method: Composition-based stats. Identities = 66/414 (15%), Positives = 125/414 (30%), Gaps = 82/414 (19%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 V IV + GK + F L+ + + I+ V N + Sbjct: 2 VAIVDVGITKFGKRKENIF------DLVKEVTEKLLK----------YDIDYVIVSNSYS 45 Query: 96 VGAGATEHRAACLASGIPYS-TPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 T ++ + + + P + ++ SG +A+ + ++ + + L +GVE Sbjct: 46 GEFNQTSGLSSLITTYLNLDYVPSLRVDNTSGSGGSAILVAKSLLESKEANTVLVVGVEK 105 Query: 155 MTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQK 214 M+ K + I S L I+ F R+ + A ++ Sbjct: 106 MS--EKKTREVTKIISSLLPFEERIASLPSLASISAIEYMRKFNAPRESIAQVAVKNHYN 163 Query: 215 AYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNAS 274 + + +E V +E L + + Sbjct: 164 GSLNPFAHIQKR------------VTLEEVLNSPVISEPL-RLYEY-------------T 197 Query: 275 QVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAY--AIPKVL 327 +SDG A V++ R A + + E PA A K Sbjct: 198 PISDGAAAVVMVRNEDALSYTSKPV-YIKGIGSSNYTAYVSEKEDFVTLPAVVEASRKAF 256 Query: 328 EATGLQVQDIDIFEINEAFAAQALYCIHKLGI------------------DLNKVNPRGG 369 + +V+ ID E+++ + +G+ +NP GG Sbjct: 257 KKA--KVERIDFAELHDMATILEIIQSEDIGLFKKGEGWKAVMEGLTSLDGEIPINPSGG 314 Query: 370 AIALGHPLGCTGARQVATIL---------RELKKDQIGVVSMCIGTGMGAAAIF 414 + GHP+G +G Q R++K ++G+ G G A I Sbjct: 315 LNSKGHPIGASGVAQAVEAFSQIRNEAGNRQVKNARVGLSLSMAGYGNSATVII 368 >5M3K-C nrPDB Length = 398 Score = 76.6 bits (187), Expect = 2e-14, Method: Composition-based stats. Identities = 72/405 (17%), Positives = 123/405 (30%), Gaps = 88/405 (21%) Query: 34 EDVVIVAANRSAI-GKGF-KGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEV--- 88 V IV+A + G + FK++ + E + + + I+ V Sbjct: 4 RRVAIVSAAYTPKPGSSRVRQTFKEM---------IVESAYKALKDAKMHPREIQAVAYG 54 Query: 89 ACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGL 148 G ++ G + L P T N C+S + + G+ DI L Sbjct: 55 YHGEGISEYGGLGPTISDALGIS-PAPTFMSTAN--CTSSSVSFQMGHQMVASGEYDIVL 111 Query: 149 ALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFA 208 G E MT+++ +G + E T E F + ++ D A Sbjct: 112 CGGFEKMTDHFNYAEYIGSSTECEYDYFLGISHTDAFALATAEYF-QKFGYAGREADVLA 170 Query: 209 ANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTT 268 Q A+N P G P + E L + G+ Sbjct: 171 TFGRQMRIYAQN--------TPTATRYGQ---------PIPSLEVLK-----NSEACGSM 208 Query: 269 TA-GNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVP---------------- 311 A G AS +L +A++ + GV Sbjct: 209 LAWGEASG------CAILVAEHLAHKYTDKPV-FVRGCAYTGVSHYFGTRFHNPTLHHPG 261 Query: 312 -PEIMGVG----PAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGI------- 359 P+ +G+ + G+ +DID+ ++ + A L + +GI Sbjct: 262 LPKDVGMAVSANSIACAEIAYKKAGITAKDIDVAQVYDLLGA-GLIQMESMGICGKGQAG 320 Query: 360 DLN-----------KVNPRGGAIALGHPLGCTGARQVATILRELK 393 D +N GG I GH GC G + + R+L+ Sbjct: 321 DFVLEGGIALDGQLPLNTDGGNIGRGHASGCDGILHITELFRQLR 365 >4U4E-A nrPDB Length = 383 Score = 64.3 bits (155), Expect = 9e-11, Method: Composition-based stats. Identities = 54/364 (14%), Positives = 103/364 (28%), Gaps = 65/364 (17%) Query: 59 TDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPF 118 D E E L ++ + + + G P T Sbjct: 23 PDKPAIALHAEAALNALEEAGLTLRDVDGLLTAGISPLELGEYLGIE-------PSYTDG 75 Query: 119 VALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNRE 178 A+ SS + + A I G+ + L E + + P + + + L+ E Sbjct: 76 TAVGG--SSFVIHLAHAAAAIVTGRCSVALITHGE--SGRSRVGMPPRVPAPDSLRGQFE 131 Query: 179 AKKCL-IPMGITNENVAAN---FKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLP 234 L P+G + + + +++ E A + + A Sbjct: 132 DPYGLPTPVGAYALACSRHMAEYGTTKEQLAEIAVATRKWAMLNPKA------------- 178 Query: 235 DGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQL 294 R +T E + + RP + V+D ++ A L Sbjct: 179 ---------YMRDPITIEDVLNSRPIVWPFN----LLDCCLVTDAGGACVVTSIERARDL 225 Query: 295 NLPVLGRY-----IDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQ 349 + D + P + + + G+ DID+ I ++F Sbjct: 226 RQHPVAILGVGESHDHSIISQMPSLTSFAARRSGQAAFKMAGVTHDDIDLAMIYDSFTYT 285 Query: 350 ALYCIHKLGI------------------DLNKVNPRGGAIALGHPLGCTGARQVATILRE 391 L + LG +N GG ++ HP G G + +R+ Sbjct: 286 VLLSLEDLGFCAKGEGGAFVSGQRTAPGGDFPMNTNGGGLSYTHP-GMYGMFAIIEAVRQ 344 Query: 392 LKKD 395 L+ D Sbjct: 345 LRHD 348 >3O04-A nrPDB Length = 413 Score = 51.2 bits (121), Expect = 8e-07, Method: Composition-based stats. Identities = 23/118 (19%), Positives = 39/118 (33%), Gaps = 14/118 (11%) Query: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEAT 330 + +G V+L A + + + G P G G A A+ ++ Sbjct: 231 IGEGAGIVILEEYEHAKARGAKIYAEIVGYGATGDAYHITAPAPNGEGAARAMKMAIDDA 290 Query: 331 GLQVQDIDIFEI-------NEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 GL +D N+ + QA+ + G K+ GH LG +G Sbjct: 291 GLTPDKVDYINAHGTSTPYNDEYETQAIKTV--FGEHAKKLAISSTKSMTGHTLGASG 346 >5W2O-A nrPDB Length = 439 Score = 50.0 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 29/132 (21%), Positives = 40/132 (30%), Gaps = 23/132 (17%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 A +L+ A L R + V P GV A+ + LE GL Sbjct: 265 AGALMLIETEEHAKARGAKPLARLLGAGITSDAFHMVAPAADGVRAGRAMTRSLELAGLS 324 Query: 334 VQDIDIFEIN----------EAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGAR 383 DID + EA A + C ALGH +G GA Sbjct: 325 PADIDHVNAHGTATPIGDAAEANAIRVAGCDQAAVYAPKS--------ALGHSIGAVGAL 376 Query: 384 QVATILRELKKD 395 + + L+ Sbjct: 377 ESVLTVLTLRDG 388 Score = 44.6 bits (104), Expect = 8e-05, Method: Composition-based stats. Identities = 13/49 (26%), Positives = 21/49 (42%) Query: 105 AACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 AA + + + CSSG A+ +I +G D+ + GVE Sbjct: 174 AAVIGLQLGARAGVMTPVSACSSGSEAIAHAWRQIVMGDADVAVCGGVE 222 >4R8E-A nrPDB Length = 413 Score = 48.5 bits (114), Expect = 5e-06, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 34/117 (29%), Gaps = 10/117 (8%) Query: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEAT 330 + DG ++L A + + + F P G G A A+ L Sbjct: 232 LGDGAGMMVLEEYEHAKKRGAKIYAEVVGFGMSSDAYHMTSPPEDGSGAALAMVNALRDA 291 Query: 331 GLQVQDIDIFEINEAFA-----AQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 G+ I + A+ G D KV GH LG GA Sbjct: 292 GITTSQIGYINAHGTSTPAGDKAETQAVKSVFGEDAYKVMVSSTKSMTGHLLGAAGA 348 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISS 170 P +++ C+SG+ + A I D+ +A G E + V G + Sbjct: 156 PSISIATACTSGVHNIGHAARIIAYNDADVMVAGGAEKAST-PLGVGGFGAARA 208 >4QAV-A nrPDB Length = 415 Score = 48.5 bits (114), Expect = 6e-06, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 34/114 (29%), Gaps = 8/114 (7%) Query: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMG---VGPAYAIPKVLEATGL 332 + +G ++L A + + + F I GPA A+ + L+ G+ Sbjct: 233 IGEGAGILVLEELEHAKKRGAKIYAEIVGFGMSSDAYHITAPNEEGPALAVTRALKDAGI 292 Query: 333 QVQDIDIFEINEAFAAQALYCI-----HKLGIDLNKVNPRGGAIALGHPLGCTG 381 +D+D + G K GH LG G Sbjct: 293 NPEDVDYVNAHGTSTPLGDANETKALKRAFGEHAYKTVVSSTKSMTGHLLGAAG 346 Score = 38.1 bits (87), Expect = 0.008, Method: Composition-based stats. Identities = 24/108 (22%), Positives = 38/108 (35%), Gaps = 16/108 (14%) Query: 46 IGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRA 105 IG + + + + E R P +LI + G+V Sbjct: 102 IGVNIGSGIGGLPSIEVTGKAVIEGGARKINPFFIPGSLIN-LISGHVT----------- 149 Query: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 + G Y P + C++G A+ + A IK G DI +A G E Sbjct: 150 --ILKG--YRGPSYGMVSACTTGAHAIGNSARLIKYGDADIMVAGGAE 193 >6QSP-A nrPDB Length = 406 Score = 48.1 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 38/97 (39%), Gaps = 4/97 (4%) Query: 108 LASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGM 167 LA + P L+ CSS A+ I++G +D + G ++++ N G Sbjct: 157 LARYLAIEGPAFTLSTACSSSSRAIISGQRLIEMGLVDAAIVGGADTLSRMPIN----GF 212 Query: 168 ISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQ 204 S E L C GIT + ++R+ Q Sbjct: 213 DSLESLSPTLCEPFCQDRQGITIGEASTLLLLTREPQ 249 >1J3N-A nrPDB Length = 408 Score = 47.3 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 36/114 (31%), Gaps = 10/114 (8%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G ++L A + + + F P G G A A+ + L+ G+ Sbjct: 232 GAGVLVLEAYEHAKKRGARIYAELVGFGRSADAHHITEPHPEGKGAALAMARALKDAGIA 291 Query: 334 VQDIDIFEINEAFA-----AQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 + + + A+ L G ++ +GH LG GA Sbjct: 292 PEQVGYINAHGTSTPVGDRAEVLAIKRVFGDHAKRLMVSSTKSMIGHLLGAAGA 345 Score = 42.7 bits (99), Expect = 3e-04, Method: Composition-based stats. Identities = 20/92 (21%), Positives = 35/92 (38%), Gaps = 7/92 (7%) Query: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES----MTNNYKN 161 A +A ++ P + C++G A+ I++G+ D+ LA G E+ M Sbjct: 142 AHIAMRYGFTGPSSTVVTACATGADALGSALRMIQLGEADLVLAGGTEAAITPMAIGAFA 201 Query: 162 VNPLGMISSEELQKNR---EAKKCLIPMGITN 190 V +EE +K + MG Sbjct: 202 VMRALSTRNEEPEKASRPFTLSRDGFVMGEGA 233 >2GP6-A nrPDB Length = 434 Score = 46.9 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 27/114 (23%), Positives = 41/114 (35%), Gaps = 12/114 (10%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G A +L+ A +L R + V P+ G +AI + ++ GL Sbjct: 259 GGALLLIETEEHAKARGANILARIMGASITSDGFHMVAPDPNGERAGHAITRAIQLAGLA 318 Query: 334 VQDIDIFEINEAFA-----AQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 DID + A+ + LG N+ ALGH +G GA Sbjct: 319 PGDIDHVNAHATGTQVGDLAEGRAINNALG--GNRPAVYAPKSALGHSVGAVGA 370 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 21/50 (42%), Gaps = 2/50 (4%) Query: 106 ACLASGIPYSTPF--VALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 A A G+ + C+SG A+ +I +G+ D + GVE Sbjct: 166 AAAAVGLERHAKAGVMTPVSACASGAEAIARAWQQIVLGEADAAICGGVE 215 >3E60-A nrPDB Length = 424 Score = 46.2 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 19/106 (17%), Positives = 35/106 (33%), Gaps = 9/106 (8%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G A V+L A + + I + G P G G ++ L+ + Sbjct: 246 GAAIVVLEELEHAKKRGARIYAEIIGYGLSGDAYHITAPSESGEGAQRSMMAALKRAQVN 305 Query: 334 VQDIDIFEINE----AFAAQALYCIHKLGIDLNKVNPRGGAIALGH 375 V ++D + A + LG +V+ ++GH Sbjct: 306 VSELDYINAHGTSTMADVIELAAVERVLGYYAPQVSMSSTKSSIGH 351 Score = 45.8 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 20/59 (33%), Positives = 26/59 (44%), Gaps = 5/59 (8%) Query: 101 TEHRAACLASGI-----PYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 R LASG P ++ CS+G A+ D A I +G D+ LA G ES Sbjct: 145 IPGRLINLASGYVSIKYGLRGPNHSVVTACSTGAHAIGDAARLIALGDADVMLAGGTES 203 >4EWP-A nrPDB Length = 350 Score = 44.2 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 17/108 (15%), Positives = 34/108 (31%), Gaps = 3/108 (2%) Query: 58 NTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYS-T 116 + + E + ++ V V AT AA +A I + Sbjct: 57 TAEETVPVMAVGAAREALERAGLQGSDLDAVIVSTVTFP--HATPSAAALVAHEIGATPA 114 Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 P ++ C+ V ++ G L +GVE +++ + Sbjct: 115 PAYDVSAACAGYCYGVAQADALVRSGTARHVLVVGVERLSDVVDPTDR 162 >4LS7-A nrPDB Length = 426 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 20/113 (17%), Positives = 38/113 (33%), Gaps = 10/113 (8%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G ++L A + G + + + G P G G A A+ + ++ G+ Sbjct: 247 GAGIIVLEELEHALARGAKIYGEIVGYGSTGDAYHITAPAQDGEGGARAMQEAIKDAGIA 306 Query: 334 VQDIDIFEINEAFA-----AQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 ++ID + + + G +K+ GH LG G Sbjct: 307 PEEIDYINAHGTSTYYNDKYETMAIKTVFGEHAHKLAVSSTKSMTGHLLGAAG 359 Score = 35.0 bits (79), Expect = 0.064, Method: Composition-based stats. Identities = 16/92 (17%), Positives = 31/92 (33%), Gaps = 8/92 (8%) Query: 105 AACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES----MTNNYK 160 +A G + C++G ++ D I+ G D+ + G E+ M+ Sbjct: 159 QISIALGA-KGVNSCTVT-ACATGTNSIGDAFKVIQRGDADVMVTGGTEAPLTRMSFAGF 216 Query: 161 NVNPLGMISSEELQKNREAKKCL--IPMGITN 190 + N + + +R K MG Sbjct: 217 SANKALSTNPDPKTASRPFDKNRDGFVMGEGA 248 >2IX4-A nrPDB Length = 431 Score = 43.8 bits (102), Expect = 1e-04, Method: Composition-based stats. Identities = 31/143 (21%), Positives = 49/143 (34%), Gaps = 23/143 (16%) Query: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG------VPPEIMGVGPAYAIPKVLEA 329 + +G ++L A + + + G PPE G G A+ + L Sbjct: 248 IGEGSGVIVLEEYEHAKRRGAKIYAELCGYGMSGDAHHITQPPED-GKGAVLAMTRALRQ 306 Query: 330 TGLQVQDIDIFEIN----------EAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGC 379 +GL ID + EA A + ++ H L + +G A GH LG Sbjct: 307 SGLCPNQIDYVNAHATSTPIGDAVEARAIKTVFSEHATSGTLAFSSTKG---ATGHLLGA 363 Query: 380 TGARQVATILRELKKDQIGVVSM 402 GA + + GV M Sbjct: 364 AGA---VEAIFSILAIHHGVAPM 383 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 17/31 (54%) Query: 124 QCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 C++G ++ D I+ G D+ +A G ES Sbjct: 178 ACATGAHSIGDATRMIQFGDADVMVAGGTES 208 >2GQD-A nrPDB Length = 437 Score = 43.5 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 17/113 (15%), Positives = 34/113 (30%), Gaps = 10/113 (8%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G +++ A + + + T G P G G + A+ ++ G++ Sbjct: 258 GAGILVIESLESAQARGANIYAEIVGYGTTGDAYHITAPAPEGEGGSRAMQAAMDDAGIE 317 Query: 334 VQDIDIFEINEAFAAQA-----LYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 +D+ + + G + GH LG TG Sbjct: 318 PKDVQYLNAHGTSTPVGDLNEVKAIKNTFGEAAKHLKVSSTKSMTGHLLGATG 370 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 26/74 (35%), Gaps = 8/74 (10%) Query: 124 QCSSGLTAVNDIANKIKVGQIDIGLALGVE----SMTNNYKNVNPLGMISSE---ELQKN 176 C++G ++ + ++ G D + G E M + + + + + Sbjct: 187 ACATGTNSIGEAFKIVQRGDADAMITGGTEAPITHMAIAGFSASRALSTNDDIETACRPF 246 Query: 177 REAKKCLIPMGITN 190 +E + + MG Sbjct: 247 QEGRDGFV-MGEGA 259 >3KZU-A nrPDB Length = 428 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 P ++ C++G A+ D A I G D+ +A G ES Sbjct: 170 PNHSVVTACATGTHAIGDAARLIAFGDADVMVAGGTES 207 Score = 41.5 bits (96), Expect = 6e-04, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 32/106 (30%), Gaps = 9/106 (8%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G V+L A + I + G P G G + L+ G+ Sbjct: 250 GAGIVVLEELEHALARGAKIYAEVIGYGMSGDAFHITAPTESGEGAQRCMVAALKRAGIV 309 Query: 334 VQDIDIFEINE----AFAAQALYCIHKLGIDLNKVNPRGGAIALGH 375 +ID + A + +G K++ ++GH Sbjct: 310 PDEIDYINAHGTSTMADTIELGAVERVVGEAAAKISMSSTKSSIGH 355 >1OXH-A nrPDB Length = 430 Score = 43.1 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 30/232 (12%), Positives = 62/232 (26%), Gaps = 20/232 (8%) Query: 63 LYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALN 122 + E + ++ + L A + ++N Sbjct: 127 GIGGIKEIEDQVLRLHEKGPKRVKPMTLPKALPNMASGNVAMR------FGANGVCKSIN 180 Query: 123 RQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREA--- 179 CSS A+ D IK G D+ L G E+ + + + + A Sbjct: 181 TACSSSNDAIGDAFRSIKFGFQDVMLVGGTEASITPFAIAGFQALTALSTTEDPTRASIP 240 Query: 180 ---KKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKNEGLFEDEILPIKLPDG 236 + MG + + + ++ + Y + P + Sbjct: 241 FDKDRNGFVMGEGSGMLVLE-SLEHAEKRGATILAEVVGYGNTCDAYHMTSPHP-EGQGA 298 Query: 237 SICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARR 288 ++ E + A++ GT+T N S G +L + Sbjct: 299 IKAIKLALEEAEISPEQV-----AYVNAHGTSTPANEKGES-GAIVAVLGKE 344 >4DDO-A nrPDB Length = 451 Score = 42.3 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 23/117 (19%), Positives = 36/117 (30%), Gaps = 17/117 (14%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP------AYAIPKVLEATGL 332 G A V++ A + I + T M GP A+ L + Sbjct: 265 GAAMVVVESLDHALARGARPIAEIIGYGTTA-DAYHMTAGPDDGSGAMRAMKLALRMGDV 323 Query: 333 QVQDIDIFEIN-------EAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 + +D + +A +AL + +G A GH LG GA Sbjct: 324 APEQVDYVNAHATSTPVGDAGEIEALKTVFGVGAGPA---ISSTKSATGHLLGAAGA 377 Score = 39.2 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 18/31 (58%) Query: 124 QCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 C++ + A+ D I+ G+ D+ LA G E+ Sbjct: 192 ACAASVQAIGDAMRMIRTGEADVVLAGGAEA 222 >4JRH-A nrPDB Length = 417 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 41/132 (31%), Gaps = 15/132 (11%) Query: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEAT 330 + DG ++L A + + F G P G G A A+ + Sbjct: 235 LGDGAGIMVLEEYEHAKARGAKIYAEVVGFGMSGDAYHMTSPSEDGSGGALAMEAAMRDA 294 Query: 331 GLQVQDIDIFEINEAFA-----AQALYCIHKLGIDLNK-VNPRGGAIALGHPLGCTGAR- 383 G+ + I + A+ LG K V GH LG G+ Sbjct: 295 GVTGEQIGYVNAHGTSTPAGDVAEVKGIKRALGEAGTKQVLVSSTKSMTGHLLGAAGSVE 354 Query: 384 ---QVATILREL 392 V +++ ++ Sbjct: 355 AIITVMSLVDQM 366 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 36/209 (17%), Positives = 60/209 (28%), Gaps = 40/209 (19%) Query: 1 MSQRLQSIKDHLVESAMGKGESKRKNSLLEKRPEDVVIVAANRSAIGKGFKG-------- 52 MS+R + + S +G +LL + V I + + F G Sbjct: 4 MSKRRVVVTGMGMLSPVGNTVESSWKALLAGQSGIVNIEHFDTTNFSTRFAGLVKGFDCE 63 Query: 53 ---AFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATE----HRA 105 + KD L + + E ++N G + G G E Sbjct: 64 QYMSKKDARKMDLFIQYGIAAGIQALEDSGLEVNEENAARIGVAIGSGIGGLELIETGHQ 123 Query: 106 ACLASG----IPYSTPFVALNR--------------------QCSSGLTAVNDIANKIKV 141 A + G P+ P +N C++GL + A I Sbjct: 124 ALIEKGPRKVSPFFVPSTIVNMIAGNLSIMRGLRGPNIAISTACTTGLHNIGHAARMIAY 183 Query: 142 GQIDIGLALGVESMTNNYKNVNPLGMISS 170 G D +A G E + + G + Sbjct: 184 GDADAMVAGGAEKAST-PLGMAGFGAAKA 211 >4JGA-A nrPDB Length = 437 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 25/114 (21%), Positives = 38/114 (33%), Gaps = 10/114 (8%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G V+L A V G I + + G P G G A+ + + Sbjct: 257 GAGVVVLEEYEHALNRGAKVYGEVIGYGSTGDAYHMTAPHPEGRGAYRAMRDAMLDATIT 316 Query: 334 VQDIDIFEINEAFA----AQALYCIHKLGIDLN-KVNPRGGAIALGHPLGCTGA 382 ID + L + KL ++ N KV ++GH LG G+ Sbjct: 317 PDMIDYINAHGTSTTLGDGIELAAVQKLFLEANPKVLMSSTKSSIGHLLGAAGS 370 Score = 40.0 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 17/59 (28%), Positives = 24/59 (40%), Gaps = 5/59 (8%) Query: 101 TEHRAACLASGI-----PYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 L SG+ +S P CS+G A+ D IK G D+ +A G E+ Sbjct: 156 IPASLINLLSGLVSIKYGFSGPNQTAVTACSTGAHAIGDAMRMIKHGYADVMIAGGAEA 214 >4JPF-A nrPDB Length = 436 Score = 39.6 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 24/116 (20%), Positives = 38/116 (32%), Gaps = 16/116 (13%) Query: 38 IVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVG 97 + ANR IG + L E R P ++I V Sbjct: 115 VTDANRERIGVSMGSGIGGLTNIENNCRSLFEQGPRRISPFFVPGSIINMV--------- 165 Query: 98 AGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE 153 + L+ + P AL C++G ++ A I G+ D+ +A G E Sbjct: 166 -------SGFLSIHLGLQGPNYALTTACTTGTHSIGMAARNIAYGEADVMVAGGSE 214 >4RYB-A nrPDB Length = 320 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 13/86 (15%), Positives = 24/86 (27%) Query: 79 RADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANK 138 D I+ + + GI P + C+ + A+ Sbjct: 68 GLDSGEIDLIIVATATPDMQFPSTATIVQQKLGITNGCPAFDVQAVCAGFMYALTTANAY 127 Query: 139 IKVGQIDIGLALGVESMTNNYKNVNP 164 IK G L +G E+ + + Sbjct: 128 IKSGMAKNALVIGAETFSRIVDWNDR 153 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 36/165 (21%), Positives = 54/165 (32%), Gaps = 32/165 (19%) Query: 278 DGVAGVLLARRSV-----------ANQLNLPVLGRYIDFQTVGVPPEIMGVGP------- 319 DG V+L+ N L L + I V P I GP Sbjct: 161 DGAGAVVLSAADKPGIIHSKLKADGNYLKLLNVPGQIACGKVSGSPYISMDGPGVFKFAV 220 Query: 320 ---AYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNP----RGGAIA 372 + V+E G ID ++A LG+ ++KV G A Sbjct: 221 KMLSKIADDVIEEAGYTAAQIDWIVPHQANRRIIESTAKHLGLSMDKVVLTVQDHGNTSA 280 Query: 373 LGHPLGC-TGARQVATILRELKKDQIGVVSMCIGTGMGAAAIFIK 416 PL TG R ++K+ Q ++ IG G A+ ++ Sbjct: 281 ASIPLALDTGIR-----SGQIKRGQ-NLLLEGIGGGFAWGAVLLQ 319 >2IWZ-A nrPDB Length = 438 Score = 38.8 bits (89), Expect = 0.004, Method: Composition-based stats. Identities = 22/117 (18%), Positives = 36/117 (30%), Gaps = 16/117 (13%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVG-----VPPEIMGVGPAYAIPKVLEATGLQ 333 G A ++L A Q + + + G P+ G G + L+ G+Q Sbjct: 258 GAAVLVLEEYEHAVQRRARIYAEVLGYGLSGDAGHITAPDPEGEGALRCMAAALKDAGVQ 317 Query: 334 VQDIDIFEINEAFAAQALY--------CIHKLGIDLNKVNPRGGAIALGHPLGCTGA 382 ++I + L + +G A GH LG GA Sbjct: 318 PEEISYINAHATSTPLGDAAENKAIKHLFKDHAYALAVSSTKG---ATGHLLGAAGA 371 Score = 35.8 bits (81), Expect = 0.036, Method: Composition-based stats. Identities = 13/38 (34%), Positives = 20/38 (52%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 P A++ C++G AV D I G D+ +A G +S Sbjct: 180 PNHAVSTACTTGAHAVGDSFRFIAHGDADVMVAGGTDS 217 >3HO9-A nrPDB Length = 427 Score = 38.8 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 12/54 (22%), Positives = 22/54 (40%), Gaps = 1/54 (1%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISS 170 P +++ +SG+ + A I G D+ +A G E + V G + Sbjct: 170 PSISIATAATSGVHNIGHAARIIAYGDADVMVAGGAEKAST-PLGVGGFGAARA 222 >4DFE-A nrPDB Length = 333 Score = 38.5 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 30/103 (29%), Gaps = 4/103 (3%) Query: 56 DVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYS 115 DV T L + R E D I+ + + GI Sbjct: 62 DVTTSDLAFIASQ----RAIEAADIDPQSIDLIIVATSTPDFVFPSTACLLQNKLGIRNH 117 Query: 116 TPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNN 158 + CS AV + I+ GQ L +G E+ + Sbjct: 118 GAAFDVQAVCSGFAYAVATADSFIRSGQHRTALVIGAETFSRI 160 >5AB6-A nrPDB Length = 425 Score = 37.3 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 62/379 (16%), Positives = 116/379 (30%), Gaps = 66/379 (17%) Query: 36 VVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLN 95 V IV R+ IGK K + D L + L + ++ + L Sbjct: 22 VRIVGVGRTGIGKLHK------SVDELAASALKCAL----VDANMKQCDLQALIAVPSLA 71 Query: 96 VGAGATEHRAACLASGIPYS--TPFVALNRQCSSGLTAVNDIANKIKVGQID---IGLAL 150 H A +A P ++ + +TA+ + ++ + + A Sbjct: 72 SPQFMQAHHIATVAGLFPTKGKFIVRTVDTGGAGPITALGMAVDLVRTRCAETVAVIAAD 131 Query: 151 GVESMTNNYKNVNPLGMISSEELQK-------NREAKKCLIPMGITNENVAANFKISRKD 203 V SM + + L + +R A+ + G+ E +A + K Sbjct: 132 AVLSMGSGAFAERSNASLRRSGLPEPCIPHGYDRYAQWYMSRYGLKREQLAMVPVLMSKM 191 Query: 204 QDEFAANSYQKAYKAKNEGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIK 263 + QKAY +E L + P+ ++D V+ E+ + A K Sbjct: 192 AERHPEAMCQKAY-TLDEVLHSRCVAPVTNLLECARRADGAVALIVSGEAHYAEHFAQGK 250 Query: 264 DRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAI 323 G + ++A + A+ P + + P+I +A Sbjct: 251 QEQRHL---------GGSKPIIASVAEASGPLFPPG------SSDDIVPDIFSC--RHAA 293 Query: 324 PKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLG------------------------I 359 + L V DI F + + F + + +G + Sbjct: 294 RDAFLSANLNVGDIHFFGLYDCFPICLIQAVEAVGLCPEGKGGEFMETAYNEMLNNGGVL 353 Query: 360 DLNK--VNPRGGAIALGHP 376 D +K +N GG G P Sbjct: 354 DPSKFPINTHGGLQCFGAP 372 >1MZJ-A nrPDB Length = 339 Score = 36.5 bits (83), Expect = 0.021, Method: Composition-based stats. Identities = 18/106 (16%), Positives = 32/106 (30%), Gaps = 1/106 (0%) Query: 59 TDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPF 118 D + R E D I+ V + N A G + Sbjct: 56 PDETIQVMGVAASRRALEHAGVDPAEIDLVVVSTMTNFVHTPPLSVAIAHELGA-DNAGG 114 Query: 119 VALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 L+ C+ A++ A+ ++ G L + E MT+ + Sbjct: 115 FDLSAACAGFCHALSIAADAVESGGSRHVLVVATERMTDVIDLADR 160 >5BY7-A nrPDB Length = 360 Score = 35.8 bits (81), Expect = 0.032, Method: Composition-based stats. Identities = 16/89 (17%), Positives = 26/89 (29%), Gaps = 1/89 (1%) Query: 63 LYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALN 122 L + ++ R + ++ V G T GI P L Sbjct: 81 LADLAHQAGSRALDAAGVTPEEVDLVVLGTATPDRLMPTTATVVADRLGI-DGVPAYQLQ 139 Query: 123 RQCSSGLTAVNDIANKIKVGQIDIGLALG 151 CS + A+ + + G L LG Sbjct: 140 SGCSGAVQALAVTRSLLLGGTARTALVLG 168 Score = 28.1 bits (61), Expect = 7.2, Method: Composition-based stats. Identities = 21/91 (23%), Positives = 35/91 (38%), Gaps = 13/91 (14%) Query: 321 YAIPKVLEATGLQVQDIDIFEINEA-----FAAQALYCIHKLGIDLNKVNPRGGAIALGH 375 A + L+A G+ +++D+ + A A +LGID G A Sbjct: 87 QAGSRALDAAGVTPEEVDLVVLGTATPDRLMPTTATVVADRLGID--------GVPAYQL 138 Query: 376 PLGCTGARQVATILRELKKDQIGVVSMCIGT 406 GC+GA Q + R L ++ +G Sbjct: 139 QSGCSGAVQALAVTRSLLLGGTARTALVLGG 169 >4X0O-A nrPDB Length = 362 Score = 35.0 bits (79), Expect = 0.056, Method: Composition-based stats. Identities = 17/100 (17%), Positives = 27/100 (27%), Gaps = 5/100 (5%) Query: 57 VNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYST 116 VNT L I + I+ + GIP S Sbjct: 50 VNTSDLATVAAQHAIA----CAGVSVEEIDLIIVATCSPDSLIPNIASRVQQNLGIP-SA 104 Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMT 156 LN C+ L + ++ L +G E ++ Sbjct: 105 AAFDLNAACTGFLYGLETATRLMQASHYRHALVIGAERLS 144 >4OQJ-A nrPDB Length = 845 Score = 35.0 bits (79), Expect = 0.067, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 16/34 (47%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 P V+ N CS+ L AV+ + G + LA Sbjct: 185 PSVSTNTACSTSLVAVHLACLSLLSGDCTMALAG 218 >1E5M-A nrPDB Length = 416 Score = 34.6 bits (78), Expect = 0.072, Method: Composition-based stats. Identities = 28/157 (17%), Positives = 49/157 (31%), Gaps = 17/157 (10%) Query: 250 TAESLSSIRPAFIKDRGTTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVG 309 + L + RP F KDR G S + ++L A + G + + Sbjct: 216 NDDPLHASRP-FDKDRDGFVMGEGSGI------LILEELESALARGAKIYGEMVGYAMTC 268 Query: 310 -----VPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQ-----ALYCIHKLGI 359 P G G AI L+ +GL+ + + + LG Sbjct: 269 DAYHITAPVPDGRGATRAIAWALKDSGLKPEMVSYINAHGTSTPANDVTETRAIKQALGN 328 Query: 360 DLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQ 396 + GH LG +G + + + +D+ Sbjct: 329 HAYNIAVSSTKSMTGHLLGGSGGIEAVATVMAIAEDK 365 Score = 32.7 bits (73), Expect = 0.29, Method: Composition-based stats. Identities = 29/235 (12%), Positives = 63/235 (26%), Gaps = 32/235 (13%) Query: 108 LASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES----MTNNYKNVN 163 L + P + C++G A+ D ++ G + G E+ ++ Sbjct: 154 LGAKGPNNCTVT----ACAAGSNAIGDAFRLVQNGYAKAMICGGTEAAITPLSYAGFASA 209 Query: 164 PLGMISSEELQ---KNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAKN 220 +++ + + + MG + I ++ E A K Y Sbjct: 210 RALSFRNDDPLHASRPFDKDRDGFVMGEGS-------GILILEELESALARGAKIYGEMV 262 Query: 221 EGLFEDEILPIKLPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRGTTTAGN-------- 272 + I P + + L ++I GT+T N Sbjct: 263 GYAMTCDAYHITAPVPDGRGATRAIAWALKDSGLKPEMVSYINAHGTSTPANDVTETRAI 322 Query: 273 ASQVSDGVAGVLLARRSVANQL------NLPVLGRYIDFQTVGVPPEIMGVGPAY 321 + + + ++ + + + VPP I P Sbjct: 323 KQALGNHAYNIAVSSTKSMTGHLLGGSGGIEAVATVMAIAEDKVPPTINLENPDP 377 >2BZ4-A nrPDB Length = 418 Score = 34.6 bits (78), Expect = 0.088, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Query: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE----SMTNNYKN 161 ACLA+ +++ C++ + + +I++G+ DI A G E M + Sbjct: 156 ACLATPFKIHGVNYSISSACATSAHCIGNAVEQIQLGKQDIVFAGGGEELCWEMACEFDA 215 Query: 162 VNPLGMISSEELQKNR 177 + L ++ +K Sbjct: 216 MGALSTKYNDTPEKAS 231 >5ENY-A nrPDB Length = 764 Score = 34.6 bits (78), Expect = 0.091, Method: Composition-based stats. Identities = 15/64 (23%), Positives = 27/64 (42%), Gaps = 8/64 (12%) Query: 117 PFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGV------ES-MTNNYKNV-NPLGMI 168 P + ++ CSS L + + +ID+ L GV ES M+ + +P G Sbjct: 334 PAIPIDTACSSSLVGTHLARQALINKEIDMALVGGVSLYLTPESYMSMCEAGMLSPDGQC 393 Query: 169 SSEE 172 + + Sbjct: 394 KAFD 397 >4XOX-A nrPDB Length = 404 Score = 33.8 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 17/76 (22%), Positives = 32/76 (42%), Gaps = 4/76 (5%) Query: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE----SMTNNYKN 161 ACLA+ +++ C++ + + I++G+ DI A G E S T + Sbjct: 142 ACLATPFKIRGVNYSISSACATSAHCIGNAVELIQLGKQDIVFAGGGEELYWSQTMMFDA 201 Query: 162 VNPLGMISSEELQKNR 177 + L +E +K Sbjct: 202 MGALSTKYNETPEKAS 217 >1TQY-A nrPDB Length = 424 Score = 33.8 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 22/130 (16%), Positives = 41/130 (31%), Gaps = 10/130 (7%) Query: 276 VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGP-----AYAIPKVLEAT 330 +++G A +L A + + T + G+ A I L+ + Sbjct: 237 LAEGAAMFVLEDYDSALARGARIHAEISGYATRCNAYHMTGLKADGREMAETIRVALDES 296 Query: 331 GLQVQDIDIFEINEAFAAQ-----ALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQV 385 DID + + Q LG + +GH LG G+ ++ Sbjct: 297 RTDATDIDYINAHGSGTRQNDRHETAAYKRALGEHARRTPVSSIKSMVGHSLGAIGSLEI 356 Query: 386 ATILRELKKD 395 A + L+ Sbjct: 357 AACVLALEHG 366 Score = 33.4 bits (75), Expect = 0.16, Method: Composition-based stats. Identities = 12/45 (26%), Positives = 21/45 (46%) Query: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLAL 150 A +A + P ++ C+SGL +V + I+ G D+ A Sbjct: 150 AEVAWAVGAEGPVTMVSTGCTSGLDSVGNAVRAIEEGSADVMFAG 194 >1UB7-A nrPDB Length = 322 Score = 33.8 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 23/131 (17%), Positives = 43/131 (32%), Gaps = 9/131 (6%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94 D IV R+ I K + A +D T L + + + + R P L ++ V Sbjct: 29 DEWIV--TRTGI-KERRVAAEDEYTSDLAFKAVEDLLRRHPGALEG----VDAVIVATNT 81 Query: 95 NVGAGATEHRAACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVES 154 A + + L C + A+ ++ G LA+G E+ Sbjct: 82 PDALFPDTA--ALVQARFGLKAFAYDLLAGCPGWIYALAQAHALVEAGLAQKVLAVGAEA 139 Query: 155 MTNNYKNVNPL 165 ++ + Sbjct: 140 LSKIIDWNDRA 150 Score = 33.4 bits (75), Expect = 0.19, Method: Composition-based stats. Identities = 11/46 (23%), Positives = 20/46 (43%) Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPR 367 A + +E GL +DI +F ++A +LG+ +V Sbjct: 225 ATLEAIEKAGLTPEDIRLFVPHQANLRIIDAARERLGLPWERVAVN 270 >6ET0-A nrPDB Length = 365 Score = 33.1 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 19/125 (15%), Positives = 43/125 (34%), Gaps = 14/125 (11%) Query: 66 FLNEFIGRFPEPLRADLNLIEEVAC----------GNVLNVGAGATEHRAACLAS---GI 112 + R + ++ + C G+VL G R A + S G+ Sbjct: 75 LVVRAAERLLRSSDTAPDSVDMLICSASSPIMTDAGDVLPDLRGRLYPRMANVLSKQLGL 134 Query: 113 PYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNPLGMISSEE 172 + P + + +S L + A+ I+ G+ + L + E ++N + + ++ Sbjct: 135 SRALPLDS-QMEAASFLLNLRLAASMIRQGKAEKVLVVCSEYISNLLDFTSRTSTLFADG 193 Query: 173 LQKNR 177 Sbjct: 194 CAVAL 198 Score = 32.7 bits (73), Expect = 0.32, Method: Composition-based stats. Identities = 15/71 (21%), Positives = 23/71 (32%), Gaps = 9/71 (12%) Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTG 381 A+ + LE GL DID F ++ +G + +G TG Sbjct: 265 AMRRALEKAGLGSDDIDYFVFHQPAPFLVKAWAEGIGARPEQYQLT---------MGDTG 315 Query: 382 ARQVATILREL 392 +I L Sbjct: 316 VMISVSIPYTL 326 >4YLT-A nrPDB Length = 316 Score = 32.3 bits (72), Expect = 0.37, Method: Composition-based stats. Identities = 15/63 (23%), Positives = 25/63 (39%), Gaps = 6/63 (9%) Query: 302 YIDFQTVGVPPEIMGVGPAYAIPKVLEATGLQVQDIDIFEI-----NEAFAAQALYCIHK 356 + + G+ + +G A K LE G+ DI + + + AF + A Sbjct: 39 IRERRIAGLDETVATMG-FQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRM 97 Query: 357 LGI 359 LGI Sbjct: 98 LGI 100 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 13/99 (13%), Positives = 30/99 (30%), Gaps = 1/99 (1%) Query: 60 DYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFV 119 D + + + E D + I + + A + GI Sbjct: 48 DETVATMGFQAAEKALEMAGIDKDDIGLIIVATTSSSHAFPSSACQVQRMLGI-KDAASF 106 Query: 120 ALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNN 158 L C+ A++ +K G + + +G + ++ Sbjct: 107 DLAAACAGFTYALSVADQYVKSGAVKHAIVIGSDVLSRA 145 >5O31-R nrPDB Length = 96 Score = 32.3 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 341 EINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIG 398 E+NE FA + + ++ GG ALGHP R + +E K G Sbjct: 34 EVNENFAIDLIAEQPVSQVGSRVISCDGGGGALGHP------RVYINLDKETKTGTCG 85 >4YUC-A nrPDB Length = 335 Score = 32.3 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 25/87 (28%), Gaps = 7/87 (8%) Query: 53 AFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVA--CGNVLNVGAGATEHRAACLAS 110 KD ++ E + L I+ + G+ L Sbjct: 52 WVKDETASFMGAEAAKEAVR----DAGLKLEDIDLIINASGSPEQAVPDGGPLVQRELGL 107 Query: 111 GIPYSTPFVALNRQCSSGLTAVNDIAN 137 G P + +N C S A++ AN Sbjct: 108 GRS-GVPSITVNASCLSFFVALDVAAN 133 >5VXG-A nrPDB Length = 358 Score = 32.3 bits (72), Expect = 0.46, Method: Composition-based stats. Identities = 24/94 (25%), Positives = 41/94 (43%), Gaps = 10/94 (10%) Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHP-LGCT 380 A +VL G V+++D F I++ + GID KV G H +G Sbjct: 267 AAKQVL---GWAVEELDQFVIHQVSRPHTAAFVKSFGIDPAKVMTIFGE----HGNIGPA 319 Query: 381 GARQVATILRELKKDQIG--VVSMCIGTGMGAAA 412 V + L+EL + + G + + IG+G+ + Sbjct: 320 SVPIVLSKLKELGRLKKGDRIALLGIGSGLNCSM 353 >5GUP-F nrPDB Length = 123 Score = 31.9 bits (71), Expect = 0.46, Method: Composition-based stats. Identities = 16/58 (27%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 341 EINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIG 398 E+NE FA + + ++ GG ALGHP R + +E K G Sbjct: 61 EVNENFAIDLIAEQPVSEVGSRVISCDGGGGALGHP------RVYINLDKETKTGTCG 112 >3IL4-A nrPDB Length = 320 Score = 31.9 bits (71), Expect = 0.48, Method: Composition-based stats. Identities = 15/107 (14%), Positives = 36/107 (33%), Gaps = 5/107 (4%) Query: 58 NTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTP 117 NT L + + + + + + I+ + V + A G + Sbjct: 50 NTSDLCHQVAKQLLEKSGKQA----SEIDFILVATVTPDFNMPSVACQVQGAIGATEAF- 104 Query: 118 FVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 ++ CS + A++ + G+ GL +G E+ + + Sbjct: 105 AFDISAACSGFVYALSMAEKLVLSGRYQTGLVIGGETFSKMLDWTDR 151 >5YO9-A nrPDB Length = 371 Score = 31.9 bits (71), Expect = 0.57, Method: Composition-based stats. Identities = 19/78 (24%), Positives = 30/78 (38%), Gaps = 11/78 (14%) Query: 320 AYAIPKVLEATGLQVQDIDIF-----EINEAFAAQALYCIHKLGID--LNKVNPRGGAIA 372 A + +E G+ +DID+ + A+ A A+ LGI +N A Sbjct: 103 VIAAKQAMENAGVTAEDIDVVILACSNMQRAYPAVAIEIQSALGIQGYAYDMNVAASAAT 162 Query: 373 LGHPLGC----TGARQVA 386 G +GAR+V Sbjct: 163 FGLKQAADAIRSGARRVL 180 >3H76-A nrPDB Length = 359 Score = 31.5 bits (70), Expect = 0.62, Method: Composition-based stats. Identities = 9/24 (37%), Positives = 14/24 (58%) Query: 320 AYAIPKVLEATGLQVQDIDIFEIN 343 A + +EA GL +DID+ +N Sbjct: 79 VPAARQAIEAAGLLPEDIDLLLVN 102 >6G2J-R nrPDB Length = 116 Score = 31.5 bits (70), Expect = 0.64, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 341 EINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIG 398 E+NE FA + ++ + GG ALGHP + + +E K G Sbjct: 54 EVNENFAIDLIAQQPVNEVEHRIIACDGGGGALGHP------KVYINLDKETKTGTCG 105 >2EBD-A nrPDB Length = 309 Score = 31.5 bits (70), Expect = 0.76, Method: Composition-based stats. Identities = 26/162 (16%), Positives = 53/162 (32%), Gaps = 34/162 (20%) Query: 278 DGVAGVLLA-RRSVANQLNLPVLG----------------RYIDFQTVGVPPEIMGVGPA 320 DG V++ ++ L + R + V M Sbjct: 158 DGAGAVVVTRSEDKSDILATRMYAEGSLEELLHADNCGYIRMKGRELFKVAVRSMEE--- 214 Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCT 380 +VLE G++ +++ + ++A KL I KV G T Sbjct: 215 -VCREVLEKAGVKPEEVSLVIPHQANVRIINALAEKLNIPKEKVFVN------IQKYGNT 267 Query: 381 GARQVATILRE------LKKDQIGVVSMCIGTGMGAAAIFIK 416 A + L E +K+ + +++ +G G+ A+ ++ Sbjct: 268 SAASIPIALHEAIKEGKVKRGDLILMTA-MGGGLTWGAVLLR 308 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/109 (12%), Positives = 33/109 (30%), Gaps = 9/109 (8%) Query: 55 KDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEH--RAACLASGI 112 K+ Y+ E + ++ + + + A L + Sbjct: 46 KEETITYMATQAAKEALR----EANLSPEELDLIILATLTPQKRFPSTACLVQAQLKA-- 99 Query: 113 PYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKN 161 ++ CS + A++ + IK G+ L +G E ++ Sbjct: 100 -KGVYAFDISAACSGFIYALDIADSFIKSGKAKNVLVIGAEKLSEAVDW 147 >5OQL-X nrPDB Length = 630 Score = 31.1 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 28/162 (17%), Positives = 50/162 (30%), Gaps = 25/162 (15%) Query: 143 QIDIGLALGVESMTNN------YKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAAN 196 + + G E ++N ++P + + + G N ++A Sbjct: 362 ESQLVFRGGGEGGSSNTKKHKLPPGMDPASAAHEGSMDRVAMIDDDMFVTGSDNGDLA-L 420 Query: 197 FKISRKDQDEFAANSYQKAYKAKNEGLFEDEI-----LPIKLPDGSICQS---------- 241 + I RK A ++ K E DEI +P P G Sbjct: 421 WSIQRKKPLHVIARAHGLEPPIKLEDYSADEIPDPSIIPAPQPRGITALRTLPYSDLIFS 480 Query: 242 ---DEGPRPNVTAESLSSIRPAFIKDRGTTTAGNASQVSDGV 280 D R +E + I G+ T N++ +S+G Sbjct: 481 GSWDGCIRVWRLSEDKRKLEAVGILGVGSETCENSTNISNGA 522 >3OA3-A nrPDB Length = 288 Score = 31.1 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 25/117 (21%), Positives = 44/117 (37%), Gaps = 17/117 (14%) Query: 48 KGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAAC 107 K + F+D+ L + I + L +E+ G VL+ AGA + + Sbjct: 155 KRYTDVFQDIRAVRLAA---KDAILKVI--LETSQLTADEIIAGCVLSSLAGADYVKTST 209 Query: 108 LASGIPYSTPFVAL-NRQCSS-----------GLTAVNDIANKIKVGQIDIGLALGV 152 +G S V+L + C S G+ + D ++ G +G + GV Sbjct: 210 GFNGPGASIENVSLMSAVCDSLQSETRVKASGGIRTIEDCVKMVRAGAERLGASAGV 266 >2AJ9-A nrPDB Length = 356 Score = 31.1 bits (69), Expect = 0.80, Method: Composition-based stats. Identities = 29/168 (17%), Positives = 56/168 (33%), Gaps = 30/168 (17%) Query: 270 AGNASQVSDGVAGVLLA--------------RRSVANQLNLPVLGRYIDFQTVGVPPEIM 315 AGN +DG A V++ A+ + + G P + Sbjct: 182 AGNCFIFADGAAAVVVGETPFQGIGPTVAGSDGEQADAIRQDIDWITFAQNPSGPRPFVR 241 Query: 316 GVGPAY----------AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVN 365 GPA + ++A G++ ID+F ++A + + L + + V Sbjct: 242 LEGPAVFRWAAFKMGDVGRRAMDAAGVRPDQIDVFVPHQANSRINELLVKNLQLRPDAVV 301 Query: 366 PRGGAIALGHPLGCTGARQVATILRELKKD--QIGVVSMCIGTGMGAA 411 + H + A + L + G +++ IG G G + Sbjct: 302 AN----DIEHTGNTSAASIPLAMAELLTTGAAKPGDLALLIGYGAGLS 345 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 15/97 (15%), Positives = 27/97 (27%), Gaps = 1/97 (1%) Query: 60 DYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFV 119 D + E R I+ V + + G Sbjct: 79 DESAASMATEACRRALSNAGLSAADIDGVIVTTNTHFLQTPPAAPMVAASLGA-KGILGF 137 Query: 120 ALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMT 156 L+ C+ A+ A+ I+ G L +G E ++ Sbjct: 138 DLSAGCAGFGYALGAAADMIRGGGAATMLVVGTEKLS 174 >5XTD-T nrPDB Length = 95 Score = 31.1 bits (69), Expect = 0.88, Method: Composition-based stats. Identities = 15/58 (25%), Positives = 23/58 (39%), Gaps = 6/58 (10%) Query: 341 EINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPLGCTGARQVATILRELKKDQIG 398 E+NE FA + ++ + GG ALGHP + + +E K G Sbjct: 34 EVNENFAIDLIAEQPVSEVETRVIACDGGGGALGHP------KVYINLDKETKTGTCG 85 >3OYT-A nrPDB Length = 410 Score = 31.1 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 15/76 (19%), Positives = 29/76 (38%), Gaps = 4/76 (5%) Query: 106 ACLASGIPYSTPFVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVE----SMTNNYKN 161 ACLA+ +++ C++ + I++G+ DI A G E M + Sbjct: 148 ACLATPFKIKGVNYSISSACATSAHCIGHALELIQLGKQDIVFAGGGEELCWEMACEFDA 207 Query: 162 VNPLGMISSEELQKNR 177 + L ++ K Sbjct: 208 MGALSTKYNDTPAKAS 223 >1DXL-A nrPDB Length = 470 Score = 31.1 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 18/60 (30%), Positives = 25/60 (41%), Gaps = 4/60 (6%) Query: 35 DVVIVAANRSAIGKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVL 94 DVV+V+A R+ G V TD L +NE + A I +V G +L Sbjct: 269 DVVLVSAGRTPFTSGLNLDKIGVETDKLGRILVNERFSTNVSGVYA----IGDVIPGPML 324 >4V2P-A nrPDB Length = 351 Score = 31.1 bits (69), Expect = 1.00, Method: Composition-based stats. Identities = 14/87 (16%), Positives = 25/87 (28%), Gaps = 7/87 (8%) Query: 53 AFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVAC--GNVLNVGAGATEHRAACLAS 110 K ++ E + L+ I+ + G+ L Sbjct: 68 WVKGETAAFMGAEAAKEAVR----DAGLQLSDIDLIISASGSPQQAVPDGGPLVQRELGL 123 Query: 111 GIPYSTPFVALNRQCSSGLTAVNDIAN 137 G TP + +N C S A+ +N Sbjct: 124 GRS-GTPAITVNASCLSFFVALEVASN 149 >5BQS-A nrPDB Length = 323 Score = 30.8 bits (68), Expect = 1.1, Method: Composition-based stats. Identities = 14/111 (12%), Positives = 35/111 (31%), Gaps = 3/111 (2%) Query: 55 KDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPY 114 + ++ + E + ++ + + AA + + I Sbjct: 42 RHISRTESTSDLATEVAKKLMAKAGITGKELDFIILATITP--DSMMPSTAARVQANIGA 99 Query: 115 STP-FVALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 + L CS + A++ I G+ GL +G E+++ + Sbjct: 100 NKAFAFDLTAACSGFVFALSTAEKFIASGRFQKGLVIGSETLSKAVDWSDR 150 >3IL7-A nrPDB Length = 313 Score = 30.4 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 19/60 (31%), Positives = 26/60 (43%), Gaps = 4/60 (6%) Query: 322 AIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNK----VNPRGGAIALGHPL 377 A +V+E L DID+F ++A +LGI +K VN G A PL Sbjct: 217 ASTRVVEKANLTSDDIDLFIPHQANIRIMESARERLGISKDKMSVSVNKYGNTSAASIPL 276 Score = 30.0 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 9/96 (9%), Positives = 23/96 (23%), Gaps = 1/96 (1%) Query: 69 EFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSG 128 E + I+ + T G + CS Sbjct: 57 EASVKAIADAGIQPEDIDMIIVATATGDMPFPTVANMLQERLGTGK-VASMDQLAACSGF 115 Query: 129 LTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 + ++ ++ G L +G + ++ + Sbjct: 116 MYSMITAKQYVQSGDYHNILVVGADKLSKITDLTDR 151 >4NHD-A nrPDB Length = 319 Score = 30.0 bits (66), Expect = 1.8, Method: Composition-based stats. Identities = 13/95 (13%), Positives = 27/95 (28%), Gaps = 1/95 (1%) Query: 70 FIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPFVALNRQCSSGL 129 D + I+ + + GI P L CS + Sbjct: 61 AAQNAINMAGIDKHDIDMIIVATTSASHTFPSAACQVQGKLGI-KGCPAFDLAAACSGFM 119 Query: 130 TAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 A++ +K G L +G ++++ + Sbjct: 120 YALSIADQHVKSGMCKHVLVIGADALSKTCDPTDR 154 >3VEW-A nrPDB Length = 576 Score = 30.0 bits (66), Expect = 2.0, Method: Composition-based stats. Identities = 10/40 (25%), Positives = 12/40 (30%), Gaps = 4/40 (10%) Query: 317 VGPAYAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHK 356 P A L GL V D+D AF + Sbjct: 50 TAPVQAAAFCLAQAGLTVDDLDAV----AFGWDLPAMYRE 85 >5OQL-Y nrPDB Length = 411 Score = 30.0 bits (66), Expect = 2.3, Method: Composition-based stats. Identities = 32/158 (20%), Positives = 50/158 (31%), Gaps = 24/158 (15%) Query: 211 SYQKAYKAKNEGLFEDEILPIK----LPDGSICQSDEGPRPNVTAESLSSIRPAFIKDRG 266 S ++ A N GL EI ++ + +GSI T + G Sbjct: 34 SKIRSSSATNPGLAPHEISFLRLLESVTNGSIIDVS---YSGTTITYQPGL------ITG 84 Query: 267 TTTAGNASQVSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPKV 326 T NAS SD + V+ A + L L F + G P V Sbjct: 85 TVPGMNASLSSDAIEHVIPATNTRGITYFLIPLALLAPFSKAHLNVRFTG-------PGV 137 Query: 327 LEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKV 364 + + +D+ I + F L GI ++ Sbjct: 138 ITSATHGARDLSI----DTFRTAVLPLYGLFGIPPARI 171 >2DVM-A nrPDB Length = 439 Score = 29.6 bits (65), Expect = 2.3, Method: Composition-based stats. Identities = 19/92 (20%), Positives = 37/92 (40%), Gaps = 14/92 (15%) Query: 279 GVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPA-YAIPKVLEATGLQVQDI 337 G A V+LA L + + + + + G G A +A ++L G++ +++ Sbjct: 164 GTAAVVLA--------GLLNALKVVGKKISEITLALFGAGAAGFATLRILTEAGVKPENV 215 Query: 338 DIFEINEAFAAQALYCIHKLGIDLNKVNPRGG 369 + E+ I +DL K+ P G Sbjct: 216 RVVEL-----VNGKPRILTSDLDLEKLFPYRG 242 >5C6U-A nrPDB Length = 435 Score = 29.6 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 25/150 (16%), Positives = 43/150 (28%), Gaps = 18/150 (12%) Query: 160 KNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISRKDQDEFAANSYQKAYKAK 219 K++ P + L+ +A + M + +A F + + D+ + S ++ Sbjct: 284 KSIGPDKVNQLRHLRFFGDADGVRLHMLRHQQILAPKFALVAEVLDQRLSESKIASWTEP 343 Query: 220 NEGLF-EDEILPIKLPDGSICQSD----------EGPRPNVTAESLSSIRPAFIKDRGTT 268 G F ++LP D P + I P+F Sbjct: 344 KGGYFISLDVLPGTARRTVALAKDVGIAVTEAGASFPYRKDPDDKNIRIAPSFPSVPDLR 403 Query: 269 TAGNASQVSDG-VAGVLLARRSVANQLNLP 297 A DG LLA L Sbjct: 404 NA------VDGLATCALLAATETLLNQGLA 427 >5BNS-A nrPDB Length = 317 Score = 29.6 bits (65), Expect = 2.7, Method: Composition-based stats. Identities = 14/106 (13%), Positives = 30/106 (28%), Gaps = 1/106 (0%) Query: 59 TDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAACLASGIPYSTPF 118 + + E R E + + I + A + GI P Sbjct: 47 PNETVSTMGFEAATRAIEMAGIEKDQIGLIVVATTSATHAFPSAACQIQSMLGI-KGCPA 105 Query: 119 VALNRQCSSGLTAVNDIANKIKVGQIDIGLALGVESMTNNYKNVNP 164 + C+ A++ +K G + L +G + + + Sbjct: 106 FDVAAACAGFTYALSVADQYVKSGAVKYALVVGSDVLARTCDPTDR 151 >4EB0-A nrPDB Length = 258 Score = 29.2 bits (64), Expect = 3.6, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 14/31 (45%), Gaps = 1/31 (3%) Query: 99 GATEHRAACLASGIPYSTPFVALNRQCSSGL 129 G R+A A G P+S ++R SG Sbjct: 7 GPNPTRSALTADG-PFSVATYTVSRLSVSGF 36 >5IPW-A nrPDB Length = 633 Score = 28.8 bits (63), Expect = 4.5, Method: Composition-based stats. Identities = 18/73 (24%), Positives = 26/73 (35%), Gaps = 7/73 (9%) Query: 47 GKGFKGAFKDVNTDYLLYNFLNEFIGRFPEPLRADLNLIEEVACGNVLNVGAGATEHRAA 106 G + + ++D +L N+ R L + I E+ G E R A Sbjct: 336 GSASRISLNYAHSDEVLRKVFNDVRFRQALSLAINREEINEILF-------NGLAEPRQA 388 Query: 107 CLASGIPYSTPFV 119 L SG PY P Sbjct: 389 SLVSGSPYFDPEW 401 >2P1R-A nrPDB Length = 299 Score = 28.4 bits (62), Expect = 5.7, Method: Composition-based stats. Identities = 22/84 (26%), Positives = 33/84 (39%), Gaps = 12/84 (14%) Query: 267 TTTAGNASQ-VSDGVAGVLLARRSVANQLNLPVLGRYIDFQTVGVPPEIMGVGPAYAIPK 325 T AG +++ ++ R VA L L LG DF T PE A+ K Sbjct: 60 TVIAGGGDGTINEVSTALIQIRDGVAPALGLLPLGTANDFATSAGIPE--------ALDK 111 Query: 326 VLEAT-GLQVQDIDIFEINE--AF 346 L+ +ID+ +N+ F Sbjct: 112 ALKLAIAGNAMEIDMAMVNDKTCF 135 >2X3E-A nrPDB Length = 331 Score = 28.4 bits (62), Expect = 5.8, Method: Composition-based stats. Identities = 24/117 (20%), Positives = 38/117 (32%), Gaps = 13/117 (11%) Query: 277 SDGVAGVLLARRSVANQLNLPVLG----RYIDFQTVGVPPEIMGVGPAYAIPKVLEATGL 332 SDG LL +V+ R G M ++ +VL+ G Sbjct: 184 SDGHQFDLLMTPAVSRAERSSGQASNYFRMDGKAVFGQAVTQMSD----SVRRVLDRVGW 239 Query: 333 QVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPR----GGAIALGHPLG-CTGARQ 384 Q D+ ++A +L + + +V G +A PL G RQ Sbjct: 240 QASDLHHLVPHQANTRILAAVADQLDLPVERVVSNIAEVGNTVAASIPLALAHGLRQ 296 >5LVW-A nrPDB Length = 413 Score = 28.4 bits (62), Expect = 6.3, Method: Composition-based stats. Identities = 20/89 (22%), Positives = 26/89 (29%), Gaps = 24/89 (26%) Query: 287 RRSVANQLNLPVLGRYIDFQT-----------VGVPPEIM--------GVGPAYAIPKVL 327 R A L LP L R G + G+ P+ + Sbjct: 235 SRESATDLGLPPLFRTAAIAAMAVVCASVVLGAGQAARALVVEKAPTRGIAPSKYTRQTD 294 Query: 328 EAT-----GLQVQDIDIFEINEAFAAQAL 351 T G ID E++ A AA AL Sbjct: 295 SRTFVSSLGRTALSIDAAEMHVARAATAL 323 >4EGJ-A nrPDB Length = 334 Score = 28.1 bits (61), Expect = 7.3, Method: Composition-based stats. Identities = 12/64 (18%), Positives = 24/64 (37%), Gaps = 3/64 (4%) Query: 142 GQIDIGLALGVESMTNNYKNVNPLGMISSEELQKNREAKKCLIPMGITNENVAANFKISR 201 G+ +A ++ + P G + + LIP G+T + A ++R Sbjct: 212 GEYTACIAG---NLDLPVIRIVPAGEFYDYHAKYIANDTQYLIPCGLTADEEARLKVLAR 268 Query: 202 KDQD 205 + D Sbjct: 269 RAFD 272 >6ET3-B nrPDB Length = 283 Score = 28.1 bits (61), Expect = 7.4, Method: Composition-based stats. Identities = 13/57 (22%), Positives = 22/57 (38%), Gaps = 12/57 (21%) Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFAAQALYCIHKLGIDLNKVNPRGGAIALGHPL 377 A+ + L+ ++ ++ID+ L L D N A +GHPL Sbjct: 40 PAVREALDEAAVKPEEIDLI--------VGLA----LSPDHLIENRDIMAPKIGHPL 84 >2IVO-A nrPDB Length = 330 Score = 27.7 bits (60), Expect = 9.6, Method: Composition-based stats. Identities = 8/27 (29%), Positives = 13/27 (48%), Gaps = 4/27 (14%) Query: 321 YAIPKVLEATGLQVQDIDIFEINEAFA 347 + K L G+ + DID+ AF+ Sbjct: 53 PLLRKALSEAGVSLDDIDVI----AFS 75 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.310 0.139 0.377 Lambda K H 0.267 0.0427 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 15,841,048 Number of Sequences: 36641 Number of extensions: 665449 Number of successful extensions: 2453 Number of sequences better than 10.0: 113 Number of HSP's better than 10.0 without gapping: 120 Number of HSP's successfully gapped in prelim test: 42 Number of HSP's that attempted gapping in prelim test: 1964 Number of HSP's gapped (non-prelim): 230 length of query: 417 length of database: 10,336,785 effective HSP length: 100 effective length of query: 317 effective length of database: 6,672,685 effective search space: 2115241145 effective search space used: 2115241145 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 60 (27.7 bits)