BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P27487 (766 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2QT9-A nrPDB 1601 0.0 2AJB-A nrPDB 1373 0.0 2GBG-A nrPDB 1303 0.0 1Z68-A nrPDB 827 0.0 4WJL-A nrPDB 469 e-132 1XFD-A nrPDB 425 e-119 5OLJ-A nrPDB 295 5e-80 5YP1-A nrPDB 210 2e-54 2ECF-A nrPDB 208 8e-54 6EOT-A nrPDB 171 8e-43 2EEP-A nrPDB 169 5e-42 4Q1V-A nrPDB 158 7e-39 6EOR-A nrPDB 149 6e-36 4HXF-B nrPDB 60 3e-09 5L8S-A nrPDB 60 5e-09 3O4I-A nrPDB 49 9e-06 3AZQ-A nrPDB 48 2e-05 6IGR-A nrPDB 39 0.007 5UW6-A nrPDB 39 0.009 5T88-A nrPDB 35 0.14 4NOX-A nrPDB 33 0.41 2D81-A nrPDB 33 0.44 3KSR-A nrPDB 33 0.53 3DYV-A nrPDB 32 0.88 2I4O-A nrPDB 31 2.1 1NLZ-A nrPDB 31 2.1 4GGR-A nrPDB 30 4.3 3TM5-A nrPDB 30 4.7 3IVU-A nrPDB 30 5.4 3GUZ-A nrPDB 30 5.5 >2QT9-A nrPDB Length = 766 Score = 1601 bits (4146), Expect = 0.0, Method: Compositional matrix adjust. Identities = 765/766 (99%), Positives = 766/766 (100%) Query: 1 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSL 60 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATAD+RKTYTLTDYLKNTYRLKLYSL Sbjct: 1 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADTRKTYTLTDYLKNTYRLKLYSL 60 Query: 61 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 120 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY Sbjct: 61 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 120 Query: 121 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 180 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL Sbjct: 121 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 180 Query: 181 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF Sbjct: 181 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 Query: 241 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 300 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL Sbjct: 241 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 300 Query: 301 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 360 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS Sbjct: 301 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 360 Query: 361 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN 420 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN Sbjct: 361 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN 420 Query: 421 EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY 480 EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY Sbjct: 421 EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY 480 Query: 481 TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY 540 TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY Sbjct: 481 TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY 540 Query: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT 600 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT Sbjct: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT 600 Query: 601 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 660 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE Sbjct: 601 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 660 Query: 661 YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS 720 YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS Sbjct: 661 YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS 720 Query: 721 KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 766 KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP Sbjct: 721 KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 766 >2AJB-A nrPDB Length = 728 Score = 1373 bits (3553), Expect = 0.0, Method: Compositional matrix adjust. Identities = 642/728 (88%), Positives = 688/728 (94%) Query: 39 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEF 98 SR+TYTLTDYLK+T+R+K Y+L+WISDHEYLYKQENNIL+FNAEYGNSS+FLENSTFDE Sbjct: 1 SRRTYTLTDYLKSTFRVKFYTLQWISDHEYLYKQENNILLFNAEYGNSSIFLENSTFDEL 60 Query: 99 GHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWS 158 G+S NDYS+SPD QFIL EYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQW+TWS Sbjct: 61 GYSTNDYSVSPDRQFILFEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITWS 120 Query: 159 PVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSP 218 PVGHKLAYVWNNDIYVK EPNL S RITWTGKE++IYNG+TDWVYEEEVFSAYSALWWSP Sbjct: 121 PVGHKLAYVWNNDIYVKNEPNLSSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWSP 180 Query: 219 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSS 278 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVR+PYPKAGA NPTVKFFVV+T +LS Sbjct: 181 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLSP 240 Query: 279 VTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWN 338 + TS QI PAS+LIGDHYLC VTW T+ERISLQW+RR QNYS++DICDYDES+GRW Sbjct: 241 NASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRWI 300 Query: 339 CLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFIT 398 VARQHIE+STTGWVGRFRP+EPHFT DGNSFYKIISNEEGY+HIC+FQ DK +CTFIT Sbjct: 301 SSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDKSNCTFIT 360 Query: 399 KGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYS 458 KG WEVIGIEALTSDYLYYISNE+KGMPGGRNLY+IQL+DYTKVTCLSCELNPERCQYYS Sbjct: 361 KGAWEVIGIEALTSDYLYYISNEHKGMPGGRNLYRIQLNDYTKVTCLSCELNPERCQYYS 420 Query: 459 VSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII 518 SFS +AKYYQLRC GPGLPLYTLHSS +DK LRVLEDNSALDKMLQ+VQMPSKKLD I Sbjct: 421 ASFSNKAKYYQLRCFGPGLPLYTLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLDVIN 480 Query: 519 LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASF 578 L+ TKFWYQMILPPHFDKSKKYPLL++VYAGPCSQK DTVFRL+WATYLASTENIIVASF Sbjct: 481 LHGTKFWYQMILPPHFDKSKKYPLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIVASF 540 Query: 579 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 638 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEA RQFSKMGFVD+KRIAIWGWSYGGYVTSM Sbjct: 541 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYVTSM 600 Query: 639 VLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV 698 VLG+GSGVFKCGIAVAPVS+WEYYDSVYTERYMGLPTPEDNLD+YRNSTVMSRAENFKQV Sbjct: 601 VLGAGSGVFKCGIAVAPVSKWEYYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENFKQV 660 Query: 699 EYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHF 758 EYLLIHGTADDNVHFQQSAQ+SKALVD GVDFQ MWYTDEDHGIAS+ AHQHIYTHMSHF Sbjct: 661 EYLLIHGTADDNVHFQQSAQLSKALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHMSHF 720 Query: 759 IKQCFSLP 766 +KQCFSLP Sbjct: 721 LKQCFSLP 728 >2GBG-A nrPDB Length = 730 Score = 1303 bits (3373), Expect = 0.0, Method: Compositional matrix adjust. Identities = 617/729 (84%), Positives = 670/729 (91%), Gaps = 3/729 (0%) Query: 40 RKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFG 99 R+TYTL DYLKNT+R+K YSLRW+SD EYLYKQENNIL+FNAE+GNSS+FLENSTF+ FG Sbjct: 1 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG 60 Query: 100 HSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSP 159 SI+DYS+SPD F+LLEYNYVKQWRHSYTASY IYDLNKRQLITEE+IPNNTQW+TWS Sbjct: 61 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 120 Query: 160 VGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPN 219 GHKLAYVW NDIYVKIEP+LPS+RIT TGKE++I+NGI DWVYEEE+F AYSALWWSPN Sbjct: 121 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 180 Query: 220 GTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSV 279 GTFLAYAQFNDT VPLIEYSFYSDESLQYPKTV +PYPKAGAVNPTVKFF+VNTDSLSS Sbjct: 181 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 240 Query: 280 TNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNC 339 T +QITAPAS+ GDHYLCDV W +++RISLQWLRRIQNYSVM ICDYD+++ WNC Sbjct: 241 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 300 Query: 340 LVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD---CTF 396 ++HIE S TGW GRFRP+EPHFT DG+SFYKI+S+++GY+HIC FQ D+K CTF Sbjct: 301 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 360 Query: 397 ITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQY 456 ITKG WEVI IEALTSDYLYYISNEYK MPGGRNLYKIQL+D+T CLSC+LNPERCQY Sbjct: 361 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY 420 Query: 457 YSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDF 516 YSVS SKEAKYYQL C GPGLPLYTLH S + K LRVLEDNSALDKMLQ+VQMPSKKLDF Sbjct: 421 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF 480 Query: 517 IILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVA 576 I+LNET+FWYQMILPPHFDKSKKYPLL+DVYAGPCSQKAD FRLNWATYLASTENIIVA Sbjct: 481 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 540 Query: 577 SFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVT 636 SFDGRGSGYQGDKIMHAIN+RLGT EVEDQIEAARQF KMGFVD+KR+AIWGWSYGGYVT Sbjct: 541 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 600 Query: 637 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 696 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK Sbjct: 601 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 660 Query: 697 QVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMS 756 QVEYLLIHGTADDNVHFQQSAQISKALVD GVDFQAMWYTDEDHGIASSTAHQHIY+HMS Sbjct: 661 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 720 Query: 757 HFIKQCFSL 765 HF++QCFSL Sbjct: 721 HFLQQCFSL 729 >1Z68-A nrPDB Length = 719 Score = 827 bits (2136), Expect = 0.0, Method: Compositional matrix adjust. Identities = 386/726 (53%), Positives = 521/726 (71%), Gaps = 10/726 (1%) Query: 41 KTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQ-ENNILVFNAEYGNSSVFLENSTFDEFG 99 + TL D L T+ K + WIS EYL++ +NNI+++N E G S L N T Sbjct: 2 RALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVN 61 Query: 100 HSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSP 159 S +Y +SPD QF+ LE +Y K WR+SYTA+Y IYDL+ + + +P Q++ WSP Sbjct: 62 AS--NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSP 119 Query: 160 VGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPN 219 VG KLAYV+ N+IY+K P P ++IT+ G+E+ I+NGI DWVYEEE+ + ALWWSPN Sbjct: 120 VGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPN 179 Query: 220 GTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSV 279 G FLAYA+FNDT++P+I YS+Y DE QYP+T+ +PYPKAGA NP V+ F+++T + V Sbjct: 180 GKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYV 237 Query: 280 TNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNC 339 ++ PA + D+Y +TW T ER+ LQWL+R+QN SV+ ICD+ E W+C Sbjct: 238 GPQ---EVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDC 294 Query: 340 LVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITK 399 ++HIE S TGW G F S P F+ D S+YKI S+++GY+HI Y + ++ IT Sbjct: 295 PKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITS 354 Query: 400 GTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYT-KVTCLSCELNPERCQYYS 458 G WE I I +T D L+Y SNE++ PG RN+Y+I + Y C++C L ERCQYY+ Sbjct: 355 GKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYT 414 Query: 459 VSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII 518 SFS AKYY L C GPG+P+ TLH D+ +++LE+N L+ L+N+Q+P +++ + Sbjct: 415 ASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLE 474 Query: 519 LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASF 578 ++E WY+MILPP FD+SKKYPLL+ VY GPCSQ +VF +NW +YLAS E +++A Sbjct: 475 VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALV 534 Query: 579 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 638 DGRG+ +QGDK+++A+ R+LG +EVEDQI A R+F +MGF+D KRIAIWGWSYGGYV+S+ Sbjct: 535 DGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSL 594 Query: 639 VLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV 698 L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL+HY+NSTVM+RAE F+ V Sbjct: 595 ALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNV 654 Query: 699 EYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHF 758 +YLLIHGTADDNVHFQ SAQI+KALV+ VDFQAMWY+D++HG+ S + H+YTHM+HF Sbjct: 655 DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGL-SGLSTNHLYTHMTHF 713 Query: 759 IKQCFS 764 +KQCFS Sbjct: 714 LKQCFS 719 >4WJL-A nrPDB Length = 719 Score = 469 bits (1206), Expect = e-132, Method: Compositional matrix adjust. Identities = 257/739 (34%), Positives = 422/739 (57%), Gaps = 36/739 (4%) Query: 39 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQEN-NILVFNAEYGNSSVFLENSTFDE 97 S +L D + + L RWI+D + +YK EN +++ N E +++ LEN+TF Sbjct: 1 SETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVT 60 Query: 98 FGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQL--ITEERIPNNT-QW 154 F S +S+SPD +++LL Y+ + + +SYTASY IY+++ R++ + + ++ Q+ Sbjct: 61 FKAS--RHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQY 118 Query: 155 VTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSAL 214 W G +L Y++ N+IY + + S R+T +GKE+II+NGI DW+YEEE+ ++ A Sbjct: 119 AAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAH 178 Query: 215 WWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTD 274 WWSP+G LA+ ND+ VP + ++ YPK + PYPKAG +NPT+K +VVN Sbjct: 179 WWSPDGERLAFLMINDSLVPTMVIPRFT--GALYPKGKQYPYPKAGQMNPTIKLYVVN-- 234 Query: 275 SLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESS 334 L T+ ++++ P S ++Y+ V W + + ++WL R QN S++ +C+ ++ Sbjct: 235 -LYGPTH--TLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCE--TTT 289 Query: 335 GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYR----HICYFQID 390 G + EM++ W+ + + EP F+ DG+ F+ + ++G R HI F I Sbjct: 290 G-----ACSKKYEMTSDTWLSQ-QNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQ 343 Query: 391 KKD----CTFITKGTWEVIGIEAL--TSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTC 444 K +T G WEVI I A T+ +Y++S E P GR LY C Sbjct: 344 SKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTE--SSPRGRQLYSASTEGLLNRQC 401 Query: 445 LSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKML 504 +SC E+C Y+ SFS +++ L C GP +P+ +LHS+ N +LE NS L + + Sbjct: 402 ISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAI 461 Query: 505 QNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWA 564 ++ ++ + +++ + Q+ LP F +Y LLL + P Q F ++W Sbjct: 462 LKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWD 521 Query: 565 TYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI 624 + L +N+IVA FDGRGSG+QG KI+ I+RRLG+ EV+DQI A + K+ ++D+KR+ Sbjct: 522 SVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRL 581 Query: 625 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYR 684 +I+G YGGY+ SM+L S +FKCG VAP++ + Y S ++ERY+G+P+ E++ Y+ Sbjct: 582 SIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQ 639 Query: 685 NSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744 ++V+ K+ L+IHGTAD VHFQ SA++ K L+ GV++ Y DE H ++ Sbjct: 640 AASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSE 699 Query: 745 STAHQHIYTHMSHFIKQCF 763 + + H+Y+ + F C Sbjct: 700 KSKY-HLYSTILKFFSDCL 717 >1XFD-A nrPDB Length = 723 Score = 425 bits (1092), Expect = e-119, Method: Compositional matrix adjust. Identities = 242/746 (32%), Positives = 397/746 (53%), Gaps = 44/746 (5%) Query: 40 RKTYTLTDYLKNTYRLKLYSLRWISDHEYLYK-QENNILVFNAEYGNSSVFLENSTFDEF 98 +K T+ D +++ +WISD E++Y+ Q+ + ++N E S+V +E + Sbjct: 2 KKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESL 61 Query: 99 GHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDL---NKRQLITEERIPNNTQWV 155 +I Y ISPD ++ L YN ++HSYT Y + + + + L E Q+ Sbjct: 62 -RAIR-YEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYA 119 Query: 156 TWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALW 215 W P G +L +++ N+IY + R+ TGKE +IYNG++DW+YEEE+ + A W Sbjct: 120 GWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHW 179 Query: 216 WSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDS 275 WSP+GT LAYA ND+ VP++E Y+ YP YPKAG+ NP++ V+ + Sbjct: 180 WSPDGTRLAYAAINDSRVPIMELPTYTGSI--YPTVKPYHYPKAGSENPSISLHVIGLNG 237 Query: 276 LSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSG 335 + +++ P + ++Y+ V WAT ++++ WL R QN S++ +CD ++G Sbjct: 238 PTH-----DLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCD--ATTG 290 Query: 336 RWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYF-------- 387 + ++H E + W+ R + EP F+ DG F+ I + +G R Y Sbjct: 291 ----VCTKKH-EDESEAWLHR-QNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQP 344 Query: 388 QIDKKDCTFITKGTWEVIGIEAL--TSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCL 445 + IT G W+V I A + +Y++S E +P R LY CL Sbjct: 345 NSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTE--DLPRRRQLYSANTVGNFNRQCL 402 Query: 446 SCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQ 505 SC+L E C Y+S SFS ++ L+C GPG+P+ T+H++ + K + LE N + K + Sbjct: 403 SCDL-VENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAIN 461 Query: 506 NVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWAT 565 + QMP + I +++ Q++ P F + YPLLL V P SQ F ++W T Sbjct: 462 DRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWET 521 Query: 566 YLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIA 625 + S+ +V DGRGSG+QG K++H + RRLG E +DQ+EA R K ++D R+A Sbjct: 522 VMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVA 581 Query: 626 IWGWSYGGYVTSMVL---GSGSG-VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLD 681 ++G YGGY+++ +L G G F CG A++P++ ++ Y S ++ERY+GL LD Sbjct: 582 VFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGL----HGLD 637 Query: 682 H--YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDED 739 + Y + V R ++ ++L+IH TAD+ +HFQ +A++ L+ ++ Y DE Sbjct: 638 NRAYEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDES 697 Query: 740 HGIASSTAHQHIYTHMSHFIKQCFSL 765 H SS+ QH+Y + +F +CF + Sbjct: 698 HYFTSSSLKQHLYRSIINFFVECFRI 723 >5OLJ-A nrPDB Length = 723 Score = 295 bits (755), Expect = 5e-80, Method: Compositional matrix adjust. Identities = 215/666 (32%), Positives = 322/666 (48%), Gaps = 46/666 (6%) Query: 102 INDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVG 161 I +Y +S G ILL + +RHSY A+ YD+ + + T+SP G Sbjct: 92 IQNYEVSSTGHHILLFTDMESIYRHSYRAAVYDYDVRRNLVKPLSEHVGKVMIPTFSPDG 151 Query: 162 HKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGT 221 +A+V +N+I++K ++T G+ + + NG TDWVYEEE F + + WS + Sbjct: 152 RMVAFVRDNNIFIKKFDFDTEVQVTTDGQINSVLNGATDWVYEEE-FGVTNLMSWSADNA 210 Query: 222 FLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTN 281 FLA+ + +++ VP Y D+ YP+ YPKAG N TV + N + T Sbjct: 211 FLAFVRSDESAVPEYRMPMYEDK--LYPEDYTYKYPKAGEKNSTVSLHLYNVADRN--TK 266 Query: 282 ATSIQITAPASMLIGDHYLCDVTWA-TQERISLQWLRRIQNYSVMDICDYDESSGRWNCL 340 + S+ I A D Y+ + + + +++ L R+QN D+ L Sbjct: 267 SVSLPIDA-------DGYIPRIAFTDNADELAVMTLNRLQN-------DFKMYYVHPKSL 312 Query: 341 VARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKG 400 V + ++ +V FT G Y +S ++G+ HI + IT G Sbjct: 313 VPKLILQDMNKRYVDSDWIQALKFTAGGGFAY--VSEKDGFAHIYLYDNKGVMHRRITSG 370 Query: 401 TWEVI---GIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYY 457 W+V G++A S ++Y S E P R +Y I L+ N Sbjct: 371 NWDVTKLYGVDA--SGTVFYQSAEES--PIRRAVYAIDAKGRKTKLSLNVGTN------- 419 Query: 458 SVSFSKEAKYYQLRCSGPGLP-LYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDF 516 FS YY S P + ++ S K LR LEDN AL + L+ + K+ Sbjct: 420 DALFSGNYAYYINTYSSAATPTVVSVFRSKGAKELRTLEDNVALRERLKAYRYNPKEFTI 479 Query: 517 IILN---ETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENI 573 I E W ++ P FD S+ YP+L+ Y+GP SQ+ + +W YLAS + Sbjct: 480 IKTQSALELNAW--IVKPIDFDPSRHYPVLMVQYSGPNSQQVLDRYSFDWEHYLAS-KGY 536 Query: 574 IVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGG 633 +VA DGRG+G +G++ +LG FE +DQI AA ++ +VD RI IWGWSYGG Sbjct: 537 VVACVDGRGTGARGEEWRKCTYMQLGVFESDDQIAAATAIGQLPYVDAARIGIWGWSYGG 596 Query: 634 YVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAE 693 Y T M L G+G FK GIAVAPV+ W +YDSVYTER+M TP++N Y+ S+ + A Sbjct: 597 YTTLMSLCRGNGTFKAGIAVAPVADWRFYDSVYTERFM--RTPKENASGYKMSSALDVAS 654 Query: 694 NFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYT 753 Q L++ G+ADDNVH Q + ++ALV + F Y D++H I H+YT Sbjct: 655 QL-QGNLLIVSGSADDNVHLQNTMLFTEALVQANIPFDMAIYMDKNHSIYGGNTRYHLYT 713 Query: 754 HMSHFI 759 + F+ Sbjct: 714 RKAKFL 719 >5YP1-A nrPDB Length = 745 Score = 210 bits (534), Expect = 2e-54, Method: Compositional matrix adjust. Identities = 187/686 (27%), Positives = 301/686 (43%), Gaps = 77/686 (11%) Query: 101 SINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVT---W 157 I DY SPDG+ +L YDL K ++ N + T Sbjct: 112 GIVDYQWSPDGKALLFPLG----------GELYFYDLTKSGRDAVRKLTNGGGFATDPKI 161 Query: 158 SPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWS 217 SP G ++++ + +++ + ++T G D I NG+ ++V +EE+ ++ WW+ Sbjct: 162 SPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGS-DTIGNGVAEFVADEEM-DRHTGYWWA 219 Query: 218 PNGTFLAYAQFNDTEVPLIE-YSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL 276 P+ +A+A+ ++T VP+ + Y Y D + + V YP AG N V+ V+ + Sbjct: 220 PDDAAIAFARIDETPVPVQKRYEVYPDRT----EVVEQRYPAAGDHNVRVQLGVIAPKTG 275 Query: 277 SSVTNATSIQITAPASMLIG---DHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDES 333 + P + +G D YL V W +R++ Q R+ ++ +++ + + Sbjct: 276 AR-----------PRWIDLGKDPDIYLARVDWRDPQRLTFQ--RQSRDQKKIELIETTLT 322 Query: 334 SGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD 393 +G LV E STT WV ++ F DG + S G+ H+ D Sbjct: 323 NGTQRTLV----TETSTT-WVPLH--NDLRFLKDGRFLWS--SERSGFEHLYVASEDGST 373 Query: 394 CTFITKGTWEVIGIEAL-TSDYLYYISNEYKGMPGGRNLYKIQLSD-----YTKVTCLSC 447 T +T+G W V + A+ + L Y+S G ++Y + LS T+ + Sbjct: 374 LTALTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEA-HVYAVPLSGGEPRRLTQAPGMHA 432 Query: 448 ELNPERCQYYSVSFSKEAKYYQLRC-SGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQN 506 + S+S + Q+ G L TL VND + D + + Sbjct: 433 ATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLL--VND-----VSDATHPYAKYRA 485 Query: 507 VQMPSKKLDFIILN-ETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQ--------KADT 557 P+ + T Y +I P FD K+YP+++ VY GP +Q ++D+ Sbjct: 486 AHQPTAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDS 545 Query: 558 VFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMG 617 F YLA + +V + D RG+ +G A+ + GT EV+DQ+ Sbjct: 546 FFN----QYLAQ-QGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQA 600 Query: 618 FVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPE 677 FVD RI ++GWS GGY+T M+L + CG+A APV+ W YD+ YTERYM L P+ Sbjct: 601 FVDPARIGVYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDL--PK 658 Query: 678 DNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTD 737 N YR ++V + + + LLIHG ADDNV F S ++ L G F+ M Y Sbjct: 659 ANEAGYREASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPG 718 Query: 738 EDHGIASSTAHQHIYTHMSHFIKQCF 763 HG+ S H Y F +C Sbjct: 719 AKHGLRGSDL-LHRYRLTEDFFARCL 743 >2ECF-A nrPDB Length = 741 Score = 208 bits (529), Expect = 8e-54, Method: Compositional matrix adjust. Identities = 198/694 (28%), Positives = 302/694 (43%), Gaps = 95/694 (13%) Query: 101 SINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNK------RQLITEERIPNNTQW 154 I DY SPD Q +L +YDL + RQL E + + Sbjct: 110 GIVDYQWSPDAQRLLFPLG----------GELYLYDLKQEGKAAVRQLTHGEGFATDAKL 159 Query: 155 VTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSAL 214 SP G ++++ +++V + ++T G I NGI ++V +EE+ ++ Sbjct: 160 ---SPKGGFVSFIRGRNLWVIDLASGRQMQLTADGST-TIGNGIAEFVADEEM-DRHTGY 214 Query: 215 WWSPNGTFLAYAQFNDTEVPLIE-YSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNT 273 WW+P+ + +AYA+ +++ VP+ + Y Y+D + + YP AG N VK V+ Sbjct: 215 WWAPDDSAIAYARIDESPVPVQKRYEVYADRT----DVIEQRYPAAGDANVQVKLGVI-- 268 Query: 274 DSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDES 333 S A + I D YL V W + +S Q R+ ++ +D+ + + Sbjct: 269 ---SPAEQAQTQWIDLGKEQ---DIYLARVNWRDPQHLSFQ--RQSRDQKKLDLVEVTLA 320 Query: 334 SGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKK- 392 S + L E S T WV + F DG+ + S G++H+ ++ID K Sbjct: 321 SNQQRVLAH----ETSPT-WVPLH--NSLRFLDDGSILWS--SERTGFQHL--YRIDSKG 369 Query: 393 DCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGR--NLYKIQLSDYTKVTCLSCELN 450 +T G W V E L D ++ G+ R +Y + L Sbjct: 370 KAAALTHGNWSVD--ELLAVDEKAGLAYFRAGIESARESQIYAVPLQGG----------Q 417 Query: 451 PERCQ----YYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALD----- 501 P+R +S SF++ A Y S P N + + L +N D Sbjct: 418 PQRLSKAPGMHSASFARNASVYVDSWSNNSTPPQIELFRANGEKIATLVENDLADPKHPY 477 Query: 502 KMLQNVQMPSKKLDFIIL----NETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQ---- 553 + Q P ++F L +T Y +I P FD +K+YP+ + VY GP SQ Sbjct: 478 ARYREAQRP---VEFGTLTAADGKTPLNYSVIKPAGFDPAKRYPVAVYVYGGPASQTVTD 534 Query: 554 ----KADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEA 609 + D +F YLA + +V S D RG+ +G A+ + GT EV DQ+ Sbjct: 535 SWPGRGDHLFN----QYLAQ-QGYVVFSLDNRGTPRRGRDFGGALYGKQGTVEVADQLRG 589 Query: 610 ARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTER 669 + +VD RI + GWS GGY+T M+L S + CG+A APV+ W YDS YTER Sbjct: 590 VAWLKQQPWVDPARIGVQGWSNGGYMTLMLLAKASDSYACGVAGAPVTDWGLYDSHYTER 649 Query: 670 YMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVD 729 YM LP D YR + V++ E + LLIHG ADDNV F S + AL G Sbjct: 650 YMDLPARNDA--GYREARVLTHIEGLRS-PLLLIHGMADDNVLFTNSTSLMSALQKRGQP 706 Query: 730 FQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCF 763 F+ M Y HG++ + A H Y F+ +C Sbjct: 707 FELMTYPGAKHGLSGADA-LHRYRVAEAFLGRCL 739 >6EOT-A nrPDB Length = 898 Score = 171 bits (434), Expect = 8e-43, Method: Compositional matrix adjust. Identities = 180/677 (26%), Positives = 287/677 (42%), Gaps = 97/677 (14%) Query: 164 LAYVWNNDIYVKIEPNLPSYRITWTG------KEDIIYNGITDWVYEEEVFSAYSALWWS 217 +A++ +NDI++ R+T+ +ED G+ +V +EE F YS WW Sbjct: 228 IAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEE-FDRYSGYWWC 286 Query: 218 PN-------GTFLA--YAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKF 268 P G L Y + +++EV +I + L+ + YPK G NP V F Sbjct: 287 PKAETTPSGGKILRILYEENDESEVEIIHVT---SPMLETRRADSFRYPKTGTANPKVTF 343 Query: 269 FV--VNTDSLSSVTNATSIQITAPASMLI-GDHYLCDVTWA-------------TQERIS 312 + + D+ + + ++ P +L G Y+ W +Q R+ Sbjct: 344 KMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQ 403 Query: 313 LQWL----------------RRIQNY--SVMDICDYDESSGRWNCL------VARQHIEM 348 + + R I++ SV + Y+E++ W + + H E Sbjct: 404 IVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEE 463 Query: 349 STTGWVGRFRPSEPHF----TLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEV 404 + + H ++ S YK S G F+ K+ IT G WEV Sbjct: 464 IEFIFASECKTGFRHLYKITSILKESKYKRSSG--GLPAPSDFKCPIKEEIAITSGEWEV 521 Query: 405 IG-----IEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSV 459 +G I+ L Y K P +LY + + +VT L+ +R +S Sbjct: 522 LGRHGSNIQVDEVRRLVYFEGT-KDSPLEHHLYVVSYVNPGEVTRLT-----DRGYSHSC 575 Query: 460 SFSKEAKYYQLRCSGPGLP----LYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLD 515 S+ ++ + S P LY L S +D + E + + + + Sbjct: 576 CISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEI 635 Query: 516 FIILNETKF-WYQMILPPH-FDKSKKYPLLLDVYAGPCSQ------KADTVFRLNWATYL 567 F + T F Y M+ PH KKYP +L +Y GP Q K FRLN L Sbjct: 636 FSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLN---TL 692 Query: 568 ASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQF-SKMGFVDNKRIAI 626 AS ++V D RGS ++G K A ++G E++DQ+E + S+ F+D R+ I Sbjct: 693 ASLGYVVVV-IDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGI 751 Query: 627 WGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNS 686 GWSYGGY++ M L S +F+ IA APV+ W +YD+ YTERYMG P+ N Y Sbjct: 752 HGWSYGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMG--HPDQNEQGYYLG 809 Query: 687 TVMSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744 +V +AE F + LL+HG D+NVHF ++ + LV G + Y E H I Sbjct: 810 SVAMQAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRV 869 Query: 745 STAHQHIYTHMSHFIKQ 761 + +H H+ H++++ Sbjct: 870 PESGEHYELHLLHYLQE 886 >2EEP-A nrPDB Length = 706 Score = 169 bits (427), Expect = 5e-42, Method: Compositional matrix adjust. Identities = 164/607 (27%), Positives = 271/607 (44%), Gaps = 61/607 (10%) Query: 135 YDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLP-----SYRITWTG 189 +D+ R++ T + +SPVG ++AYV N+++Y+ L + +T G Sbjct: 106 FDMLARKVTYLFDTNEETASLDFSPVGDRVAYVRNHNLYIARGGKLGEGMSRAIAVTIDG 165 Query: 190 KEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEV---PLIEYSFYSDESL 246 E ++Y V++ E F +WSP G+ LA+ + + + V P+++Y ES Sbjct: 166 TETLVYG---QAVHQRE-FGIEKGTFWSPKGSCLAFYRMDQSMVKPTPIVDYHPLEAESK 221 Query: 247 QYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWA 306 + YP AG + V + + + +V +Q P + +L +++W+ Sbjct: 222 P------LYYPMAGTPSHHVTVGIYHLATGKTV----YLQTGEPK-----EKFLTNLSWS 266 Query: 307 TQERIS-LQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFT 365 E I + + R QN ++ YD +GR+ R + +V P P Sbjct: 267 PDENILYVAEVNRAQNECKVNA--YDAETGRF----VRTLFVETDKHYV---EPLHPLTF 317 Query: 366 LDG-NSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEAL--TSDYLYYISNEY 422 L G N+ + S +G+ H+ + + +TKG WEV LY+ S E Sbjct: 318 LPGSNNQFIWQSRRDGWNHLYLYDTTGRLIRQVTKGEWEVTNFAGFDPKGTRLYFESTE- 376 Query: 423 KGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTL 482 P R+ Y I + K L+ E R Q S S +Q P +P Sbjct: 377 -ASPLERHFYCIDIKG-GKTKDLTPESGMHRTQL-SPDGSAIIDIFQ----SPTVPRKVT 429 Query: 483 HSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIIL--NETKFWYQMILPPHFDKSKKY 540 +++ KG L + D MP + I+ +T +Y++ +P HFD +KKY Sbjct: 430 VTNIG-KGSHTLLEAKNPDT---GYAMPEIRTGTIMAADGQTPLYYKLTMPLHFDPAKKY 485 Query: 541 PLLLDVYAGPCSQKADTVFRLN---WATYLASTENIIVASFDGRGSGYQGDKIMHAINRR 597 P+++ VY GP +Q +R + W Y+A + V + D RGS +G I+RR Sbjct: 486 PVIVYVYGGPHAQLVTKTWRSSVGGWDIYMAQ-KGYAVFTVDSRGSANRGAAFEQVIHRR 544 Query: 598 LGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 657 LG E+ DQ+ +VD RI + GWSYGG++T+ ++ + VFK G+A PV Sbjct: 545 LGQTEMADQMCGVDFLKSQSWVDADRIGVHGWSYGGFMTTNLMLTHGDVFKVGVAGGPVI 604 Query: 658 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA 717 W Y+ +Y ERY P++N + Y + ++ RA + K +LIHG D V +Q S Sbjct: 605 DWNRYEIMYGERY--FDAPQENPEGYDAANLLKRAGDLKG-RLMLIHGAIDPVVVWQHSL 661 Query: 718 QISKALV 724 A V Sbjct: 662 LFLDACV 668 >4Q1V-A nrPDB Length = 710 Score = 158 bits (400), Expect = 7e-39, Method: Compositional matrix adjust. Identities = 164/670 (24%), Positives = 282/670 (42%), Gaps = 81/670 (12%) Query: 123 QWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPS 182 Q + + +Y+ Q+++ + + + +AY +N++YV + Sbjct: 89 QMLFTIAGKFIVYNFKNNQVVSTFKPKDGANNEDYCAASGNVAYTIDNNLYVNEK----- 143 Query: 183 YRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFND---TEVPLIEYS 239 T + + I G T V+ E F +WSP G LA+ + ++ T+ PL+ Sbjct: 144 ---AVTNEPEGIVCGQT--VHRNE-FGINKGTFWSPKGNLLAFYRMDESMVTQYPLV--- 194 Query: 240 FYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHY 299 D + + + V YP AG + VK + N + SI + A D Y Sbjct: 195 ---DITARVGEVNNVRYPMAGMTSHQVKVGIYNPAT------GKSIYLNAGDPT---DRY 242 Query: 300 LCDVTWATQER-ISLQWLRRIQNYSVMDICDYDESSGR-WNCLVARQHIEMSTTGWVGRF 357 +++WA E+ + L + R QN++ +C Y+ +G L H + F Sbjct: 243 FTNISWAPDEKSLYLIEVNRDQNHA--KLCQYNAETGEPMGVLYEEMHPKYVEPQNPIVF 300 Query: 358 RPSEPHFTLDGNSFYKIISNEEGYRHI---------------------CYFQIDKKDCTF 396 P +P + + S +GY H+ YFQ K Sbjct: 301 LPWDP-------TKFIYQSQRDGYNHLYLFETNAANMKGETYNSANGGSYFQAGK--VKQ 351 Query: 397 ITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQY 456 +TKG W V I + I +G+ G + + +S+ +S + Sbjct: 352 LTKGNWLVSEILGFNTKRKEVIFTAVEGLRSGH--FAVNVSNGK----ISQPFENCKESE 405 Query: 457 YSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDF 516 +S + S Y R S P + + V+ K + + + QMPS + Sbjct: 406 HSGTLSASGTYLIDRYSTKDQP--RVINLVDTKNFKETANLLTAENPYDGYQMPSIETGT 463 Query: 517 IILNE--TKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFR---LNWATYLASTE 571 I + T Y+++ P +FD +KKYP+++ VY GP +Q ++ W TY+AS + Sbjct: 464 IKAADGTTDLHYRLMKPANFDPAKKYPVIVYVYGGPHAQCVTGGWQNGARGWDTYMAS-K 522 Query: 572 NIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSY 631 I+ + D RGS +G +A RRLG E +DQ++ + +VD++RI + GWS+ Sbjct: 523 GYIMFTIDNRGSSNRGLTFENATFRRLGIEEGKDQVKGVEFLKSLPYVDSERIGVHGWSF 582 Query: 632 GGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSR 691 GG++T+ ++ +FK G+A PV W YY+ +Y ERYM TPE N + Y+ + + Sbjct: 583 GGHMTTALMLRYPEIFKVGVAGGPVIDWGYYEIMYGERYMD--TPESNPEGYKECNLKNL 640 Query: 692 AENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHI 751 A+ K L+IH DD Q + KA VD Y H +A H+ Sbjct: 641 ADQLKG-HLLIIHDDHDDTCVPQHTLSFMKACVDARTYPDLFIYPCHKHNVAGRD-RVHL 698 Query: 752 YTHMSHFIKQ 761 + ++ + +Q Sbjct: 699 HEKITRYFEQ 708 >6EOR-A nrPDB Length = 869 Score = 149 bits (375), Expect = 6e-36, Method: Compositional matrix adjust. Identities = 167/675 (24%), Positives = 265/675 (39%), Gaps = 91/675 (13%) Query: 164 LAYVWNNDIYVKIEPNLPSYRITWTGK------EDIIYNGITDWVYEEEVFSAYSALWWS 217 +++ N+D++V R+T+ + +D G+ +V +EE F ++ WW Sbjct: 201 FSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVATFVIQEE-FDRFTGYWWC 259 Query: 218 PNGTFLAYAQFNDTEVPLIEYSFYSDESLQYP-------KTVRVPYPKAGAVNPTV--KF 268 P ++ + E E + P KT YP+ G+ NP + K Sbjct: 260 PTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDSYRYPRTGSKNPKIALKL 319 Query: 269 FVVNTDSLSSVTNATSIQITAPASMLIGD-HYLCDVTWATQERIS--------LQWLRRI 319 TDS + + ++ P S L Y+ W + + QWL+ + Sbjct: 320 AEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGKYAWAMFLDRPQQWLQLV 379 Query: 320 QNYSVMDICDYDESSGRWNCLVARQH-------IEMSTTGWVGR---FRPSEPHFTLDGN 369 + I + R A E T W+ F P D Sbjct: 380 LLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWINVHDIFYPFPQSEGEDEL 439 Query: 370 SFYKIISNEEGYRHICY----------------------FQIDKKDCTFITKGTWEVIG- 406 F + + G+ H+ F+ K+ +T G WEV+ Sbjct: 440 CFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCPIKEEIALTSGEWEVLAR 499 Query: 407 ----IEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFS 462 I L Y K P +LY + ++ L+ C S +F Sbjct: 500 HGSKIWVNEETKLVYFQGT-KDTPLEHHLYVVSYEAAGEIVRLTTPGFSHSCSM-SQNFD 557 Query: 463 KEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQ-----MPSKKLDFI 517 +Y + P + +Y L +D + + M++ +P + F Sbjct: 558 MFVSHYSSVSTPPCVHVYKLSGPDDDP---LHKQPRFWASMMEAASCPPDYVPPEIFHFH 614 Query: 518 ILNETKFWYQMILPPH-FDKSKKYPLLLDVYAGPCSQKADTVF------RLNWATYLAST 570 ++ + Y MI PH KK+P +L VY GP Q + F RLN LAS Sbjct: 615 TRSDVRL-YGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIKYLRLN---TLASL 670 Query: 571 ENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQF--SKMGFVDNKRIAIWG 628 +V DGRGS +G + A+ ++G E+EDQ+E QF K GF+D R+AI G Sbjct: 671 GYAVVV-IDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGL-QFVAEKYGFIDLSRVAIHG 728 Query: 629 WSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTV 688 WSYGG+++ M L VFK IA APV+ W YD+ YTERYM + PE+N Y +V Sbjct: 729 WSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDV--PENNQHGYEAGSV 786 Query: 689 MSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASST 746 E + L++HG D+NVHF + + L+ G +Q Y +E H I Sbjct: 787 ALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERHSIRCPE 846 Query: 747 AHQHIYTHMSHFIKQ 761 + +H + HF+++ Sbjct: 847 SGEHYEVTLLHFLQE 861 >4HXF-B nrPDB Length = 622 Score = 60.5 bits (145), Expect = 3e-09, Method: Compositional matrix adjust. Identities = 61/243 (25%), Positives = 110/243 (45%), Gaps = 17/243 (6%) Query: 525 WYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGS- 583 WY + P + +K P+++ V+ GP K + + L +++ + + RGS Sbjct: 366 WY---IKPEIKEGEKAPVIVFVHGGP---KGMYGYYFKYEMQLMASKGYYIVYVNPRGSN 419 Query: 584 GYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMG-FVDNKRIAIWGWSYGGYVTSMVLGS 642 GY D + + R G + +D + +F ++ D +RI I G SYGGY+T+ L + Sbjct: 420 GYSEDFALRVLER-TGLEDFQDILNGIEEFLRLEPQADRERIGITGISYGGYMTNWAL-T 477 Query: 643 GSGVFKCGIAVAPVSRW----EYYD-SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQ 697 S +FK GI+ +S W + D ++ ++ + P +N ++YR + + A+N K Sbjct: 478 QSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGDNPLEN-ENYRKLSPLFYAKNVK- 535 Query: 698 VEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSH 757 LLIH D QS L D+G + + HG + + +H Sbjct: 536 APLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFKKGAHGHSIRGSPRHRMKRYKL 595 Query: 758 FIK 760 F++ Sbjct: 596 FME 598 >5L8S-A nrPDB Length = 604 Score = 59.7 bits (143), Expect = 5e-09, Method: Compositional matrix adjust. Identities = 52/222 (23%), Positives = 95/222 (42%), Gaps = 13/222 (5%) Query: 547 YAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQ 606 + GP S + +FR + ++ I +F RGS G + G D Sbjct: 378 HGGPQSAER-KMFRSMFQCFINRGYTIFAPNF--RGSTGYGSAFTKLVELDWGEGPRLDC 434 Query: 607 IEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAV-APVSRWEYYDSV 665 I + GF D ++ + G SYGGY+ ++ G S F+ + + P + + +SV Sbjct: 435 IAGIEWLFESGFTDRNKLFLVGGSYGGYMALLLHGRHSDYFRAVVDIFGPSDLFTFINSV 494 Query: 666 ------YTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQI 719 ER++G PE + + + + ++ + + L+I G D V ++S QI Sbjct: 495 PPHWKPIMERWLG--DPERDKERFIKDSPVTYLDGMVK-PMLVIQGAKDPRVVKEESDQI 551 Query: 720 SKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 L + G D + + DE HG + +Y+ M F+++ Sbjct: 552 VAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVYSLMLAFLEK 593 >3O4I-A nrPDB Length = 582 Score = 48.9 bits (115), Expect = 9e-06, Method: Compositional matrix adjust. Identities = 54/213 (25%), Positives = 94/213 (44%), Gaps = 26/213 (12%) Query: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTE----NIIVASFDGRGSGYQGDKIMHAINR 596 P ++ V+ GP ++ +D+ W T+ AS ++++ ++ G +GY + + I Sbjct: 361 PTVVLVHGGPFAEDSDS-----WDTFAASLAAAGFHVVMPNYRGS-TGYGEEWRLKIIGD 414 Query: 597 RLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV 656 G E+ED AAR + G + I G+SYGGY+T L G+FK G+A A V Sbjct: 415 PCGG-ELEDVSAAARWARESGLASE--LYIMGYSYGGYMTLCALTMKPGLFKAGVAGASV 471 Query: 657 SRW----EYYDSV---YTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADD 709 W E D+ + E+ G + + R+ + ++ + K+ LIH Sbjct: 472 VDWEEMYELSDAAFRNFIEQLTG-----GSREIMRSRSPINHVDRIKE-PLALIHPQNAS 525 Query: 710 NVHFQQSAQISKALVDVGVDFQAMWYTDEDHGI 742 + ++ L+ G F+A D H I Sbjct: 526 RTPLKPLLRLMGELLARGKTFEAHIIPDAGHAI 558 >3AZQ-A nrPDB Length = 662 Score = 47.8 bits (112), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 58/245 (23%), Positives = 105/245 (42%), Gaps = 20/245 (8%) Query: 510 PSKKLDFIILNETKFWYQMILPPH-----FDKSKKYPLLLDVYAGPCSQKADTVFRLNWA 564 P ++ + + + I PPH + P ++ + GP S + V L+ A Sbjct: 389 PEPQIRTFTAPDGREIHAHIYPPHSPDFTGPADELPPYVVMAHGGPTS-RVPAVLDLDVA 447 Query: 565 TYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI 624 + ++ I VA + GS G + R G +VED A ++ G D R+ Sbjct: 448 YF--TSRGIGVADVNYGGSTGYGRAYRERLRGRWGVVDVEDCAAVATALAEEGTADRARL 505 Query: 625 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV--------SRWEYYDSVYTERYMGLPTP 676 A+ G + GG+ + L S + V+ CG + PV ++S Y + +G + Sbjct: 506 AVRGGAAGGWTAASSLVS-TDVYACGTVLYPVLDLLGWADGGTHDFESRYLDFLIG--SF 562 Query: 677 EDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYT 736 E+ + YR+ ++RA+ + V +LL+ G D +Q + +A+ GV + + Sbjct: 563 EEFPERYRDRAPLTRADRVR-VPFLLLQGLEDPVCPPEQCDRFLEAVAGCGVPHAYLSFE 621 Query: 737 DEDHG 741 E HG Sbjct: 622 GEGHG 626 >6IGR-A nrPDB Length = 656 Score = 39.3 bits (90), Expect = 0.007, Method: Compositional matrix adjust. Identities = 59/264 (22%), Positives = 107/264 (40%), Gaps = 24/264 (9%) Query: 507 VQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATY 566 V+ P + L E + W ++LP + +K P LL+++ GP + D Sbjct: 399 VREPQRVTFETELGEGEGW--VLLP---EGEQKVPALLNIHGGPHT---DYGHGFTHEFQ 450 Query: 567 LASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEA-ARQFSKMGFVDNKRIA 625 L + V + RGS G + AI R GT + +D + R + +D + A Sbjct: 451 LMAARGYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDADDLLNFFDRCLEAVPRLDAAKTA 510 Query: 626 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED--NLDHY 683 + G +YGG++T+ + G + F+ I +S + +GL +D LD Sbjct: 511 VMGGAYGGFMTNWITGHTT-RFQAAITDRCISNLISFGGTSD---IGLRFWDDELGLDFS 566 Query: 684 RNSTVMSR--------AENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWY 735 R + + EN K L++H D +Q+ Q AL V + + + Sbjct: 567 RRADALKLWDLSPLQYVENVK-TPTLIVHSVLDHRCPVEQAEQWYAALHKHQVPVRFVRF 625 Query: 736 TDEDHGIASSTAHQHIYTHMSHFI 759 +E+H ++ S T ++ + Sbjct: 626 PEENHELSRSGRPDRRLTRLNEYF 649 >5UW6-A nrPDB Length = 750 Score = 38.9 bits (89), Expect = 0.009, Method: Compositional matrix adjust. Identities = 32/148 (21%), Positives = 56/148 (37%), Gaps = 15/148 (10%) Query: 519 LNETKFWYQMILPPHFDKSKKYPLLLDVYAG-------PCSQKADTVFRLNWATYLASTE 571 + ++F + + P D +K P+ + G PC F +N +++ Sbjct: 464 FDRSEFEVKQVFVPSKDGTK-IPIFIAARKGISLDGSHPCEMHGYGGFGINMMPTFSASR 522 Query: 572 NIIVASFDG-------RGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI 624 + + G RG G G++ A R +D I AA G+ +R+ Sbjct: 523 IVFLKHLGGVFCLANIRGGGEYGEEWHKAGFRDKKQNVFDDFISAAEYLISSGYTKARRV 582 Query: 625 AIWGWSYGGYVTSMVLGSGSGVFKCGIA 652 AI G S GG + + + +F C A Sbjct: 583 AIEGGSNGGLLVAACINQRPDLFGCAEA 610 >5T88-A nrPDB Length = 616 Score = 34.7 bits (78), Expect = 0.14, Method: Compositional matrix adjust. Identities = 49/204 (24%), Positives = 74/204 (36%), Gaps = 11/204 (5%) Query: 566 YLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIA 625 +L I+A+ G GS Y G++ A R +D I + K G+ ++A Sbjct: 419 FLKRGGTFIMANLRG-GSEY-GEEWHRAGMRENKQNVFDDFIAVLEKLKKEGY----KVA 472 Query: 626 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS---RWE--YYDSVYTERYMGLPTPEDNL 680 WG S GG + S L V + PV R+ Y SV+ Y P+D Sbjct: 473 AWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYGNPEDPKDRE 532 Query: 681 DHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDH 740 + S + K L+ G DD VH + + L ++G T H Sbjct: 533 FLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPVYLRVETKSGH 592 Query: 741 GIASSTAHQHIYTHMSHFIKQCFS 764 AS T + F+ + S Sbjct: 593 MGASPETRARELTDLLAFVLKTLS 616 >4NOX-A nrPDB Length = 746 Score = 33.1 bits (74), Expect = 0.41, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 31/66 (46%), Gaps = 7/66 (10%) Query: 94 TFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQ 153 T D +G I D P G+++ + W+H+ Y +YD K +L+ EE I Q Sbjct: 576 TGDHYG--ITDVEWDPSGRYVA---TWASAWKHTMENGYHLYDF-KGELLREEHIEKFKQ 629 Query: 154 WVTWSP 159 W W P Sbjct: 630 W-QWRP 634 >2D81-A nrPDB Length = 318 Score = 33.1 bits (74), Expect = 0.44, Method: Compositional matrix adjust. Identities = 30/112 (26%), Positives = 51/112 (45%), Gaps = 10/112 (8%) Query: 619 VDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAV---AP--VSRWEYYDSVYTERYMGL 673 V+ +++ G + GGY+ + + + S VF G V P +R +YY S Y + Sbjct: 8 VNPNSVSVSGLASGGYMAAQLGVAYSDVFNVGFGVFAGGPYDCARNQYYTSCMYNGYPSI 67 Query: 674 PTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADD----NVHFQQSAQISK 721 TP N+ + + + S A N Q + + G++D NV Q AQ+ Sbjct: 68 TTPTANMKSWSGNQIASVA-NLGQRKIYMWTGSSDTTVGPNVMNQLKAQLGN 118 >3KSR-A nrPDB Length = 290 Score = 32.7 bits (73), Expect = 0.53, Method: Compositional matrix adjust. Identities = 23/67 (34%), Positives = 36/67 (53%), Gaps = 6/67 (8%) Query: 574 IVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAA-RQFSKMGFVDNKRIAIWGWSYG 632 I +FD RG ++G M R D I+AA Q + + +VD IA+ G SYG Sbjct: 57 ICMTFDLRG--HEGYASMRQSVTRAQNL---DDIKAAYDQLASLPYVDAHSIAVVGLSYG 111 Query: 633 GYVTSMV 639 GY+++++ Sbjct: 112 GYLSALL 118 >3DYV-A nrPDB Length = 251 Score = 32.3 bits (72), Expect = 0.88, Method: Compositional matrix adjust. Identities = 36/158 (22%), Positives = 67/158 (42%), Gaps = 23/158 (14%) Query: 623 RIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYD-------SVYTERYMG--- 672 ++ ++G S GG L + G+ G+ +P+ +++ + Y R G Sbjct: 94 KVFVFGLSLGGIFAMKALETLPGITAGGVFSSPILPGKHHLVPGFLKYAEYMNRLAGKSD 153 Query: 673 --------LPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALV 724 LP +D + +TV + KQ ++ G D+ V + + Q+ AL+ Sbjct: 154 ESTQILAYLPGQLAAIDQFA-TTVAADLNLVKQPTFIGQAGQ-DELVDGRLAYQLRDALI 211 Query: 725 DVG-VDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 + VDF WY D H I ++AH + + F++Q Sbjct: 212 NAARVDFH--WYDDAKHVITVNSAHHALEEDVIAFMQQ 247 >2I4O-A nrPDB Length = 458 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 23/102 (22%), Positives = 47/102 (46%), Gaps = 9/102 (8%) Query: 37 ADSRKTYT--LTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENST 94 A +RK+Y YL+ R+ L ++ ++ + ++ + AE G S V+++ Sbjct: 188 AGARKSYNKMFVAYLRTFARMGLKAIPMRAETGPIGGDLSHEFIVLAETGESGVYIDR-- 245 Query: 95 FDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYD 136 D + D ++ DG + +KQW Y A+ D+++ Sbjct: 246 -DVLNLPVPDENVDYDGDLTPI----IKQWTSVYAATEDVHE 282 >1NLZ-A nrPDB Length = 330 Score = 30.8 bits (68), Expect = 2.1, Method: Compositional matrix adjust. Identities = 20/76 (26%), Positives = 37/76 (48%), Gaps = 2/76 (2%) Query: 438 DYTKVTCL-SC-ELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLE 495 + T CL SC + P+R + S+ +Y + CSG L TLH+ +++ L Sbjct: 226 NITSADCLKSCLRMRPDRIILGELRSSEAYDFYNVLCSGHKGTLTTLHAGSSEEAFIRLA 285 Query: 496 DNSALDKMLQNVQMPS 511 + S+ + +N++ S Sbjct: 286 NMSSSNSAARNIKFES 301 >4GGR-A nrPDB Length = 115 Score = 30.0 bits (66), Expect = 4.3, Method: Compositional matrix adjust. Identities = 13/27 (48%), Positives = 18/27 (66%) Query: 254 VPYPKAGAVNPTVKFFVVNTDSLSSVT 280 +PYP AG+V+PT +FVV +S T Sbjct: 50 IPYPAAGSVSPTGLYFVVTFAQCNSFT 76 >3TM5-A nrPDB Length = 373 Score = 29.6 bits (65), Expect = 4.7, Method: Compositional matrix adjust. Identities = 19/45 (42%), Positives = 23/45 (51%), Gaps = 3/45 (6%) Query: 668 ERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVH 712 ER TP NLDH V+ RAE K V +L I T D ++H Sbjct: 148 ERLSRFGTPLVNLDH---PAVIFRAELIKDVFFLGIDTTGDSSLH 189 >3IVU-A nrPDB Length = 423 Score = 29.6 bits (65), Expect = 5.4, Method: Compositional matrix adjust. Identities = 18/47 (38%), Positives = 25/47 (53%), Gaps = 2/47 (4%) Query: 686 STVMSRAENFKQVEYLLIHGTADDNVHF--QQSAQISKALVDVGVDF 730 S +SR NF +E L G N F ++ QI+KAL + GVD+ Sbjct: 31 SDFLSRVNNFSIIESTLREGEQFANAFFDTEKKIQIAKALDNFGVDY 77 >3GUZ-A nrPDB Length = 176 Score = 29.6 bits (65), Expect = 5.5, Method: Composition-based stats. Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 12/91 (13%) Query: 648 KCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLD------HYRN-STVMSRAENFKQVEY 700 K + AP + Y + T Y+ +P L+ H+R ST++S+ N Q + Sbjct: 86 KVDLVFAPSVKEIYPNGTETHTYVDVPGLSTMLEGASRPGHFRGVSTIVSKLFNLVQPD- 144 Query: 701 LLIHGTADDNVHFQQSAQISKALVDVGVDFQ 731 + G D FQQ A I K + D+G D + Sbjct: 145 IACFGEKD----FQQLALIRKMVADMGFDIE 171 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2QT9-A nrPDB 1163 0.0 2AJB-A nrPDB 1054 0.0 2GBG-A nrPDB 1034 0.0 1Z68-A nrPDB 891 0.0 4WJL-A nrPDB 805 0.0 1XFD-A nrPDB 796 0.0 5OLJ-A nrPDB 651 0.0 5YP1-A nrPDB 629 0.0 2ECF-A nrPDB 612 e-175 4Q1V-A nrPDB 589 e-168 2EEP-A nrPDB 565 e-161 6EOR-A nrPDB 553 e-158 6EOT-A nrPDB 538 e-153 5L8S-A nrPDB 237 2e-62 4HXF-B nrPDB 228 1e-59 3AZQ-A nrPDB 216 3e-56 3O4I-A nrPDB 188 7e-48 Sequences not found previously or not previously below threshold: 6IGR-A nrPDB 143 3e-34 5T88-A nrPDB 107 2e-23 4AMY-A nrPDB 98 1e-20 3MUN-A nrPDB 97 3e-20 2BKL-A nrPDB 95 8e-20 1YR2-A nrPDB 91 2e-18 3WYD-A nrPDB 78 1e-14 4HVT-A nrPDB 78 2e-14 5UW6-A nrPDB 76 6e-14 5AOA-A nrPDB 74 2e-13 5JRK-A nrPDB 70 3e-12 5TXC-A nrPDB 69 5e-12 2XE4-A nrPDB 68 2e-11 5N4B-A nrPDB 68 2e-11 4BP8-A nrPDB 68 2e-11 4Q3K-A nrPDB 61 2e-09 1C7J-A nrPDB 59 6e-09 5V5V-A nrPDB 58 1e-08 3KSR-A nrPDB 57 3e-08 3FCY-A nrPDB 54 2e-07 6AAE-A nrPDB 52 1e-06 5XB6-A nrPDB 49 7e-06 6AVW-A nrPDB 49 8e-06 3HXK-A nrPDB 49 8e-06 3DYV-A nrPDB 48 2e-05 6GI5-A nrPDB 47 2e-05 4V2I-A nrPDB 47 3e-05 2HDW-A nrPDB 47 3e-05 2WQZ-A nrPDB 47 4e-05 2OCI-A nrPDB 46 4e-05 3BIX-A nrPDB 46 5e-05 5DWD-A nrPDB 45 1e-04 3HEA-A nrPDB 45 1e-04 6GUD-A nrPDB 44 2e-04 4B6G-A nrPDB 44 2e-04 3I6Y-A nrPDB 44 3e-04 1THG-A nrPDB 44 3e-04 6FKX-A nrPDB 44 3e-04 1K4Y-A nrPDB 44 3e-04 1C5K-A nrPDB 43 4e-04 3E4D-A nrPDB 43 4e-04 2YYS-A nrPDB 43 5e-04 3FNB-A nrPDB 43 5e-04 4WY8-A nrPDB 43 6e-04 1MX5-A nrPDB 42 7e-04 5FV4-A nrPDB 42 0.001 2YH2-A nrPDB 42 0.001 5X6S-A nrPDB 42 0.001 5HFN-A nrPDB 42 0.001 1AZW-A nrPDB 42 0.001 2D81-A nrPDB 42 0.001 2X8B-A nrPDB 41 0.002 4WY5-A nrPDB 41 0.002 3RLI-A nrPDB 41 0.002 3LS2-A nrPDB 41 0.002 4BZW-A nrPDB 41 0.002 1Q83-A nrPDB 41 0.002 4R40-A nrPDB 41 0.003 2JBW-A nrPDB 41 0.003 3RAR-A nrPDB 41 0.003 3FCX-A nrPDB 41 0.003 2XLB-A nrPDB 40 0.004 5XKS-A nrPDB 39 0.006 1LLF-A nrPDB 39 0.007 5YHP-A nrPDB 39 0.008 4NOX-A nrPDB 39 0.011 4DGQ-A nrPDB 38 0.014 2C7B-A nrPDB 38 0.018 1XRN-A nrPDB 38 0.019 1MPX-A nrPDB 38 0.019 4PF1-A nrPDB 37 0.021 1LNS-A nrPDB 37 0.026 2W6C-X nrPDB 37 0.027 3EBL-A nrPDB 37 0.033 1GZ7-A nrPDB 37 0.041 5LZ5-A nrPDB 36 0.046 1UFO-A nrPDB 36 0.051 5L2P-A nrPDB 36 0.052 5FDF-A nrPDB 36 0.054 4HZN-A nrPDB 36 0.055 3WMR-A nrPDB 36 0.062 3WLA-A nrPDB 36 0.087 1NX9-A nrPDB 35 0.11 1ODT-C nrPDB 35 0.11 3FM0-A nrPDB 35 0.14 6EIC-C nrPDB 35 0.15 5CXX-A nrPDB 35 0.16 5GQY-A nrPDB 34 0.22 6BX3-A nrPDB 34 0.22 6AGQ-A nrPDB 34 0.24 4QWW-A nrPDB 34 0.33 5HQ3-A nrPDB 34 0.36 3FOB-A nrPDB 33 0.41 5JOY-A nrPDB 33 0.46 2E3J-A nrPDB 33 0.51 5W8P-A nrPDB 33 0.52 5XMC-A nrPDB 32 0.65 4ZWN-A nrPDB 32 0.69 1PV1-A nrPDB 32 1.4 6FYY-p nrPDB 31 1.4 5K1H-B nrPDB 31 1.7 5A0Y-C nrPDB 31 1.7 4U1F-A nrPDB 31 1.9 2PCM-A nrPDB 31 2.6 3AV7-A nrPDB 31 2.7 1X0M-A nrPDB 31 2.7 3NC3-A nrPDB 30 3.2 4G5X-A nrPDB 30 3.7 3IB3-A nrPDB 30 4.7 5MP7-A nrPDB 30 4.9 >2QT9-A nrPDB Length = 766 Score = 1163 bits (3007), Expect = 0.0, Method: Composition-based stats. Identities = 765/766 (99%), Positives = 766/766 (100%) Query: 1 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSL 60 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATAD+RKTYTLTDYLKNTYRLKLYSL Sbjct: 1 MKTPWKVLLGLLGAAALVTIITVPVVLLNKGTDDATADTRKTYTLTDYLKNTYRLKLYSL 60 Query: 61 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 120 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY Sbjct: 61 RWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNY 120 Query: 121 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 180 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL Sbjct: 121 VKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNL 180 Query: 181 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF Sbjct: 181 PSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 Query: 241 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 300 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL Sbjct: 241 YSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYL 300 Query: 301 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 360 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS Sbjct: 301 CDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPS 360 Query: 361 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN 420 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN Sbjct: 361 EPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEALTSDYLYYISN 420 Query: 421 EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY 480 EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY Sbjct: 421 EYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLY 480 Query: 481 TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY 540 TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY Sbjct: 481 TLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKY 540 Query: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT 600 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT Sbjct: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT 600 Query: 601 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 660 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE Sbjct: 601 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 660 Query: 661 YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS 720 YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS Sbjct: 661 YYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQIS 720 Query: 721 KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 766 KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP Sbjct: 721 KALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSLP 766 >2AJB-A nrPDB Length = 728 Score = 1054 bits (2726), Expect = 0.0, Method: Composition-based stats. Identities = 642/728 (88%), Positives = 688/728 (94%) Query: 39 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEF 98 SR+TYTLTDYLK+T+R+K Y+L+WISDHEYLYKQENNIL+FNAEYGNSS+FLENSTFDE Sbjct: 1 SRRTYTLTDYLKSTFRVKFYTLQWISDHEYLYKQENNILLFNAEYGNSSIFLENSTFDEL 60 Query: 99 GHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWS 158 G+S NDYS+SPD QFIL EYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQW+TWS Sbjct: 61 GYSTNDYSVSPDRQFILFEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWITWS 120 Query: 159 PVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSP 218 PVGHKLAYVWNNDIYVK EPNL S RITWTGKE++IYNG+TDWVYEEEVFSAYSALWWSP Sbjct: 121 PVGHKLAYVWNNDIYVKNEPNLSSQRITWTGKENVIYNGVTDWVYEEEVFSAYSALWWSP 180 Query: 219 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSS 278 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVR+PYPKAGA NPTVKFFVV+T +LS Sbjct: 181 NGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRIPYPKAGAENPTVKFFVVDTRTLSP 240 Query: 279 VTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWN 338 + TS QI PAS+LIGDHYLC VTW T+ERISLQW+RR QNYS++DICDYDES+GRW Sbjct: 241 NASVTSYQIVPPASVLIGDHYLCGVTWVTEERISLQWIRRAQNYSIIDICDYDESTGRWI 300 Query: 339 CLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFIT 398 VARQHIE+STTGWVGRFRP+EPHFT DGNSFYKIISNEEGY+HIC+FQ DK +CTFIT Sbjct: 301 SSVARQHIEISTTGWVGRFRPAEPHFTSDGNSFYKIISNEEGYKHICHFQTDKSNCTFIT 360 Query: 399 KGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYS 458 KG WEVIGIEALTSDYLYYISNE+KGMPGGRNLY+IQL+DYTKVTCLSCELNPERCQYYS Sbjct: 361 KGAWEVIGIEALTSDYLYYISNEHKGMPGGRNLYRIQLNDYTKVTCLSCELNPERCQYYS 420 Query: 459 VSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII 518 SFS +AKYYQLRC GPGLPLYTLHSS +DK LRVLEDNSALDKMLQ+VQMPSKKLD I Sbjct: 421 ASFSNKAKYYQLRCFGPGLPLYTLHSSSSDKELRVLEDNSALDKMLQDVQMPSKKLDVIN 480 Query: 519 LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASF 578 L+ TKFWYQMILPPHFDKSKKYPLL++VYAGPCSQK DTVFRL+WATYLASTENIIVASF Sbjct: 481 LHGTKFWYQMILPPHFDKSKKYPLLIEVYAGPCSQKVDTVFRLSWATYLASTENIIVASF 540 Query: 579 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 638 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEA RQFSKMGFVD+KRIAIWGWSYGGYVTSM Sbjct: 541 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEATRQFSKMGFVDDKRIAIWGWSYGGYVTSM 600 Query: 639 VLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV 698 VLG+GSGVFKCGIAVAPVS+WEYYDSVYTERYMGLPTPEDNLD+YRNSTVMSRAENFKQV Sbjct: 601 VLGAGSGVFKCGIAVAPVSKWEYYDSVYTERYMGLPTPEDNLDYYRNSTVMSRAENFKQV 660 Query: 699 EYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHF 758 EYLLIHGTADDNVHFQQSAQ+SKALVD GVDFQ MWYTDEDHGIAS+ AHQHIYTHMSHF Sbjct: 661 EYLLIHGTADDNVHFQQSAQLSKALVDAGVDFQTMWYTDEDHGIASNMAHQHIYTHMSHF 720 Query: 759 IKQCFSLP 766 +KQCFSLP Sbjct: 721 LKQCFSLP 728 >2GBG-A nrPDB Length = 730 Score = 1034 bits (2674), Expect = 0.0, Method: Composition-based stats. Identities = 617/729 (84%), Positives = 670/729 (91%), Gaps = 3/729 (0%) Query: 40 RKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLENSTFDEFG 99 R+TYTL DYLKNT+R+K YSLRW+SD EYLYKQENNIL+FNAE+GNSS+FLENSTF+ FG Sbjct: 1 RRTYTLADYLKNTFRVKSYSLRWVSDSEYLYKQENNILLFNAEHGNSSIFLENSTFEIFG 60 Query: 100 HSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSP 159 SI+DYS+SPD F+LLEYNYVKQWRHSYTASY IYDLNKRQLITEE+IPNNTQW+TWS Sbjct: 61 DSISDYSVSPDRLFVLLEYNYVKQWRHSYTASYSIYDLNKRQLITEEKIPNNTQWITWSQ 120 Query: 160 VGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPN 219 GHKLAYVW NDIYVKIEP+LPS+RIT TGKE++I+NGI DWVYEEE+F AYSALWWSPN Sbjct: 121 EGHKLAYVWKNDIYVKIEPHLPSHRITSTGKENVIFNGINDWVYEEEIFGAYSALWWSPN 180 Query: 220 GTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSV 279 GTFLAYAQFNDT VPLIEYSFYSDESLQYPKTV +PYPKAGAVNPTVKFF+VNTDSLSS Sbjct: 181 GTFLAYAQFNDTGVPLIEYSFYSDESLQYPKTVWIPYPKAGAVNPTVKFFIVNTDSLSST 240 Query: 280 TNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNC 339 T +QITAPAS+ GDHYLCDV W +++RISLQWLRRIQNYSVM ICDYD+++ WNC Sbjct: 241 TTTIPMQITAPASVTTGDHYLCDVAWVSEDRISLQWLRRIQNYSVMAICDYDKTTLVWNC 300 Query: 340 LVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD---CTF 396 ++HIE S TGW GRFRP+EPHFT DG+SFYKI+S+++GY+HIC FQ D+K CTF Sbjct: 301 PTTQEHIETSATGWCGRFRPAEPHFTSDGSSFYKIVSDKDGYKHICQFQKDRKPEQVCTF 360 Query: 397 ITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQY 456 ITKG WEVI IEALTSDYLYYISNEYK MPGGRNLYKIQL+D+T CLSC+LNPERCQY Sbjct: 361 ITKGAWEVISIEALTSDYLYYISNEYKEMPGGRNLYKIQLTDHTNKKCLSCDLNPERCQY 420 Query: 457 YSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDF 516 YSVS SKEAKYYQL C GPGLPLYTLH S + K LRVLEDNSALDKMLQ+VQMPSKKLDF Sbjct: 421 YSVSLSKEAKYYQLGCRGPGLPLYTLHRSTDQKELRVLEDNSALDKMLQDVQMPSKKLDF 480 Query: 517 IILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVA 576 I+LNET+FWYQMILPPHFDKSKKYPLL+DVYAGPCSQKAD FRLNWATYLASTENIIVA Sbjct: 481 IVLNETRFWYQMILPPHFDKSKKYPLLIDVYAGPCSQKADAAFRLNWATYLASTENIIVA 540 Query: 577 SFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVT 636 SFDGRGSGYQGDKIMHAIN+RLGT EVEDQIEAARQF KMGFVD+KR+AIWGWSYGGYVT Sbjct: 541 SFDGRGSGYQGDKIMHAINKRLGTLEVEDQIEAARQFLKMGFVDSKRVAIWGWSYGGYVT 600 Query: 637 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 696 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK Sbjct: 601 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 660 Query: 697 QVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMS 756 QVEYLLIHGTADDNVHFQQSAQISKALVD GVDFQAMWYTDEDHGIASSTAHQHIY+HMS Sbjct: 661 QVEYLLIHGTADDNVHFQQSAQISKALVDAGVDFQAMWYTDEDHGIASSTAHQHIYSHMS 720 Query: 757 HFIKQCFSL 765 HF++QCFSL Sbjct: 721 HFLQQCFSL 729 >1Z68-A nrPDB Length = 719 Score = 891 bits (2303), Expect = 0.0, Method: Composition-based stats. Identities = 385/726 (53%), Positives = 521/726 (71%), Gaps = 10/726 (1%) Query: 41 KTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQ-ENNILVFNAEYGNSSVFLENSTFDEFG 99 + TL D L T+ K + WIS EYL++ +NNI+++N E G S L N T Sbjct: 2 RALTLKDILNGTFSYKTFFPNWISGQEYLHQSADNNIVLYNIETGQSYTILSNRTMKSVN 61 Query: 100 HSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSP 159 S +Y +SPD QF+ LE +Y K WR+SYTA+Y IYDL+ + + +P Q++ WSP Sbjct: 62 AS--NYGLSPDRQFVYLESDYSKLWRYSYTATYYIYDLSNGEFVRGNELPRPIQYLCWSP 119 Query: 160 VGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPN 219 VG KLAYV+ N+IY+K P P ++IT+ G+E+ I+NGI DWVYEEE+ + ALWWSPN Sbjct: 120 VGSKLAYVYQNNIYLKQRPGDPPFQITFNGRENKIFNGIPDWVYEEEMLATKYALWWSPN 179 Query: 220 GTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSV 279 G FLAYA+FNDT++P+I YS+Y DE QYP+T+ +PYPKAGA NP V+ F+++T + V Sbjct: 180 GKFLAYAEFNDTDIPVIAYSYYGDE--QYPRTINIPYPKAGAKNPVVRIFIIDTTYPAYV 237 Query: 280 TNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNC 339 ++ PA + D+Y +TW T ER+ LQWL+R+QN SV+ ICD+ E W+C Sbjct: 238 GP---QEVPVPAMIASSDYYFSWLTWVTDERVCLQWLKRVQNVSVLSICDFREDWQTWDC 294 Query: 340 LVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITK 399 ++HIE S TGW G F S P F+ D S+YKI S+++GY+HI Y + ++ IT Sbjct: 295 PKTQEHIEESRTGWAGGFFVSTPVFSYDAISYYKIFSDKDGYKHIHYIKDTVENAIQITS 354 Query: 400 GTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYT-KVTCLSCELNPERCQYYS 458 G WE I I +T D L+Y SNE++ PG RN+Y+I + Y C++C L ERCQYY+ Sbjct: 355 GKWEAINIFRVTQDSLFYSSNEFEEYPGRRNIYRISIGSYPPSKKCVTCHLRKERCQYYT 414 Query: 459 VSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII 518 SFS AKYY L C GPG+P+ TLH D+ +++LE+N L+ L+N+Q+P +++ + Sbjct: 415 ASFSDYAKYYALVCYGPGIPISTLHDGRTDQEIKILEENKELENALKNIQLPKEEIKKLE 474 Query: 519 LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASF 578 ++E WY+MILPP FD+SKKYPLL+ VY GPCSQ +VF +NW +YLAS E +++A Sbjct: 475 VDEITLWYKMILPPQFDRSKKYPLLIQVYGGPCSQSVRSVFAVNWISYLASKEGMVIALV 534 Query: 579 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 638 DGRG+ +QGDK+++A+ R+LG +EVEDQI A R+F +MGF+D KRIAIWGWSYGGYV+S+ Sbjct: 535 DGRGTAFQGDKLLYAVYRKLGVYEVEDQITAVRKFIEMGFIDEKRIAIWGWSYGGYVSSL 594 Query: 639 VLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV 698 L SG+G+FKCGIAVAPVS WEYY SVYTER+MGLPT +DNL+HY+NSTVM+RAE F+ V Sbjct: 595 ALASGTGLFKCGIAVAPVSSWEYYASVYTERFMGLPTKDDNLEHYKNSTVMARAEYFRNV 654 Query: 699 EYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHF 758 +YLLIHGTADDNVHFQ SAQI+KALV+ VDFQAMWY+D++HG++ + H+YTHM+HF Sbjct: 655 DYLLIHGTADDNVHFQNSAQIAKALVNAQVDFQAMWYSDQNHGLSG-LSTNHLYTHMTHF 713 Query: 759 IKQCFS 764 +KQCFS Sbjct: 714 LKQCFS 719 >4WJL-A nrPDB Length = 719 Score = 805 bits (2080), Expect = 0.0, Method: Composition-based stats. Identities = 255/740 (34%), Positives = 419/740 (56%), Gaps = 36/740 (4%) Query: 39 SRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQEN-NILVFNAEYGNSSVFLENSTFDE 97 S +L D + + L RWI+D + +YK EN +++ N E +++ LEN+TF Sbjct: 1 SETRLSLEDLFRKDFVLHDPEARWINDTDVVYKSENGHVIKLNIETNATTLLLENTTFVT 60 Query: 98 FGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQL--ITEERIPNNT-QW 154 F S +S+SPD +++LL Y+ + + +SYTASY IY+++ R++ + + ++ Q+ Sbjct: 61 FKAS--RHSVSPDLKYVLLAYDVKQIFHYSYTASYVIYNIHTREVWELNPPEVEDSVLQY 118 Query: 155 VTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSAL 214 W G +L Y++ N+IY + + S R+T +GKE+II+NGI DW+YEEE+ ++ A Sbjct: 119 AAWGVQGQQLIYIFENNIYYQPDIKSSSLRLTSSGKEEIIFNGIADWLYEEELLHSHIAH 178 Query: 215 WWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTD 274 WWSP+G LA+ ND+ VP + ++ YPK + PYPKAG +NPT+K +VVN Sbjct: 179 WWSPDGERLAFLMINDSLVPTMVIPRFTG--ALYPKGKQYPYPKAGQMNPTIKLYVVNLY 236 Query: 275 SLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESS 334 + ++++ P S ++Y+ V W + + ++WL R QN S++ +C+ ++ Sbjct: 237 GPTH-----TLELMPPDSFKSREYYITMVKWVSNTKTVVRWLNRAQNISILTVCET--TT 289 Query: 335 GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYR----HICYFQID 390 G + EM++ W+ + + EP F+ DG+ F+ + ++G R HI F I Sbjct: 290 G-----ACSKKYEMTSDTWLSQ-QNEEPVFSRDGSKFFMTVPVKQGGRGEFHHIAMFLIQ 343 Query: 391 KKD----CTFITKGTWEVIGIEAL--TSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTC 444 K +T G WEVI I A T+ +Y++S E P GR LY C Sbjct: 344 SKSEQITVRHLTSGNWEVIKILAYDETTQKIYFLSTE--SSPRGRQLYSASTEGLLNRQC 401 Query: 445 LSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKML 504 +SC E+C Y+ SFS +++ L C GP +P+ +LHS+ N +LE NS L + + Sbjct: 402 ISCNFMKEQCTYFDASFSPMNQHFLLFCEGPRVPVVSLHSTDNPAKYFILESNSMLKEAI 461 Query: 505 QNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWA 564 ++ ++ + +++ + Q+ LP F +Y LLL + P Q F ++W Sbjct: 462 LKKKIGKPEIKILHIDDYELPLQLSLPKDFMDRNQYALLLIMDEEPGGQLVTDKFHIDWD 521 Query: 565 TYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI 624 + L +N+IVA FDGRGSG+QG KI+ I+RRLG+ EV+DQI A + K+ ++D+KR+ Sbjct: 522 SVLIDMDNVIVARFDGRGSGFQGLKILQEIHRRLGSVEVKDQITAVKFLLKLPYIDSKRL 581 Query: 625 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYR 684 +I+G YGGY+ SM+L S +FKCG VAP++ + Y S ++ERY+G+P+ E++ Y+ Sbjct: 582 SIFGKGYGGYIASMILKSDEKLFKCGSVVAPITDLKLYASAFSERYLGMPSKEEST--YQ 639 Query: 685 NSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744 ++V+ K+ L+IHGTAD VHFQ SA++ K L+ GV++ Y DE H ++ Sbjct: 640 AASVLHNVHGLKEENILIIHGTADTKVHFQHSAELIKHLIKAGVNYTMQVYPDEGHNVSE 699 Query: 745 STAHQHIYTHMSHFIKQCFS 764 + H+Y+ + F C Sbjct: 700 K-SKYHLYSTILKFFSDCLK 718 >1XFD-A nrPDB Length = 723 Score = 796 bits (2056), Expect = 0.0, Method: Composition-based stats. Identities = 237/744 (31%), Positives = 393/744 (52%), Gaps = 40/744 (5%) Query: 40 RKTYTLTDYLKNTYRLKLYSLRWISDHEYLYK-QENNILVFNAEYGNSSVFLENSTFDEF 98 +K T+ D +++ +WISD E++Y+ Q+ + ++N E S+V +E + Sbjct: 2 KKKVTVEDLFSEDFKIHDPEAKWISDTEFIYREQKGTVRLWNVETNTSTVLIEGKKIESL 61 Query: 99 GHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDL---NKRQLITEERIPNNTQWV 155 Y ISPD ++ L YN ++HSYT Y + + + + L E Q+ Sbjct: 62 RA--IRYEISPDREYALFSYNVEPIYQHSYTGYYVLSKIPHGDPQSLDPPEVSNAKLQYA 119 Query: 156 TWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALW 215 W P G +L +++ N+IY + R+ TGKE +IYNG++DW+YEEE+ + A W Sbjct: 120 GWGPKGQQLIFIFENNIYYCAHVGKQAIRVVSTGKEGVIYNGLSDWLYEEEILKTHIAHW 179 Query: 216 WSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDS 275 WSP+GT LAYA ND+ VP++E Y+ YP YPKAG+ NP++ V+ + Sbjct: 180 WSPDGTRLAYAAINDSRVPIMELPTYTGSI--YPTVKPYHYPKAGSENPSISLHVIGLNG 237 Query: 276 LSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSG 335 + +++ P + ++Y+ V WAT ++++ WL R QN S++ +CD ++G Sbjct: 238 PTH-----DLEMMPPDDPRMREYYITMVKWATSTKVAVTWLNRAQNVSILTLCD--ATTG 290 Query: 336 RWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYF-------- 387 + ++H E + W+ R + EP F+ DG F+ I + +G R Y Sbjct: 291 ----VCTKKH-EDESEAWLHR-QNEEPVFSKDGRKFFFIRAIPQGGRGKFYHITVSSSQP 344 Query: 388 QIDKKDCTFITKGTWEVIGIEAL--TSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCL 445 + IT G W+V I A + +Y++S E +P R LY CL Sbjct: 345 NSSNDNIQSITSGDWDVTKILAYDEKGNKIYFLSTE--DLPRRRQLYSANTVGNFNRQCL 402 Query: 446 SCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQ 505 SC+L E C Y+S SFS ++ L+C GPG+P+ T+H++ + K + LE N + K + Sbjct: 403 SCDL-VENCTYFSASFSHSMDFFLLKCEGPGVPMVTVHNTTDKKKMFDLETNEHVKKAIN 461 Query: 506 NVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWAT 565 + QMP + I +++ Q++ P F + YPLLL V P SQ F ++W T Sbjct: 462 DRQMPKVEYRDIEIDDYNLPMQILKPATFTDTTHYPLLLVVDGTPGSQSVAEKFEVSWET 521 Query: 566 YLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIA 625 + S+ +V DGRGSG+QG K++H + RRLG E +DQ+EA R K ++D R+A Sbjct: 522 VMVSSHGAVVVKCDGRGSGFQGTKLLHEVRRRLGLLEEKDQMEAVRTMLKEQYIDRTRVA 581 Query: 626 IWGWSYGGYVTSMVLGSGSG----VFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLD 681 ++G YGGY+++ +L + F CG A++P++ ++ Y S ++ERY+GL ++ Sbjct: 582 VFGKDYGGYLSTYILPAKGENQGQTFTCGSALSPITDFKLYASAFSERYLGLHGLDNRA- 640 Query: 682 HYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHG 741 Y + V R ++ ++L+IH TAD+ +HFQ +A++ L+ ++ Y DE H Sbjct: 641 -YEMTKVAHRVSALEEQQFLIIHPTADEKIHFQHTAELITQLIRGKANYSLQIYPDESHY 699 Query: 742 IASSTAHQHIYTHMSHFIKQCFSL 765 SS+ QH+Y + +F +CF + Sbjct: 700 FTSSSLKQHLYRSIINFFVECFRI 723 >5OLJ-A nrPDB Length = 723 Score = 651 bits (1679), Expect = 0.0, Method: Composition-based stats. Identities = 227/750 (30%), Positives = 352/750 (46%), Gaps = 48/750 (6%) Query: 24 PVVLLNKG--TDDATADS-RKTYTLTDYLKNTYRLKLYS--LRWISDHEY---LYKQENN 75 PV++L G T A A + K L + + + +R + D E+ + ++ Sbjct: 4 PVIILLLGIVTMCAMAQTGDKPVDLKEITSGMFYARSAGRGIRSMPDGEHYTEMNRERTA 63 Query: 76 ILVFNAEYGNS--SVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYD 133 I+ +N G + ++F + I +Y +S G ILL + +RHSY A+ Sbjct: 64 IVRYNYASGKAVDTLFSIERARECPFKQIQNYEVSSTGHHILLFTDMESIYRHSYRAAVY 123 Query: 134 IYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDI 193 YD+ + + T+SP G +A+V +N+I++K ++T G+ + Sbjct: 124 DYDVRRNLVKPLSEHVGKVMIPTFSPDGRMVAFVRDNNIFIKKFDFDTEVQVTTDGQINS 183 Query: 194 IYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVR 253 + NG TDWVYEEE F + + WS + FLA+ + +++ VP Y D+ YP+ Sbjct: 184 VLNGATDWVYEEE-FGVTNLMSWSADNAFLAFVRSDESAVPEYRMPMYEDK--LYPEDYT 240 Query: 254 VPYPKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQ-ERIS 312 YPKAG N TV + N + T + S+ I A D Y+ + + + ++ Sbjct: 241 YKYPKAGEKNSTVSLHLYNVADRN--TKSVSLPIDA-------DGYIPRIAFTDNADELA 291 Query: 313 LQWLRRIQNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFY 372 + L R+QN D+ LV + ++ +V FT G Y Sbjct: 292 VMTLNRLQN-------DFKMYYVHPKSLVPKLILQDMNKRYVDSDWIQALKFTAGGGFAY 344 Query: 373 KIISNEEGYRHICYFQIDKKDCTFITKGTWEVIGIEA-LTSDYLYYISNEYKGMPGGRNL 431 +S ++G+ HI + IT G W+V + S ++Y S E P R + Sbjct: 345 --VSEKDGFAHIYLYDNKGVMHRRITSGNWDVTKLYGVDASGTVFYQSAE--ESPIRRAV 400 Query: 432 YKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLP-LYTLHSSVNDKG 490 Y I L+ N FS YY S P + ++ S K Sbjct: 401 YAIDAKGRKTKLSLNVGTN-------DALFSGNYAYYINTYSSAATPTVVSVFRSKGAKE 453 Query: 491 LRVLEDNSALDKMLQNVQMPSKKLDFIILNE-TKFWYQMILPPHFDKSKKYPLLLDVYAG 549 LR LEDN AL + L+ + K+ I + ++ P FD S+ YP+L+ Y+G Sbjct: 454 LRTLEDNVALRERLKAYRYNPKEFTIIKTQSALELNAWIVKPIDFDPSRHYPVLMVQYSG 513 Query: 550 PCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEA 609 P SQ+ + +W YLAS + +VA DGRG+G +G++ +LG FE +DQI A Sbjct: 514 PNSQQVLDRYSFDWEHYLAS-KGYVVACVDGRGTGARGEEWRKCTYMQLGVFESDDQIAA 572 Query: 610 ARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTER 669 A ++ +VD RI IWGWSYGGY T M L G+G FK GIAVAPV+ W +YDSVYTER Sbjct: 573 ATAIGQLPYVDAARIGIWGWSYGGYTTLMSLCRGNGTFKAGIAVAPVADWRFYDSVYTER 632 Query: 670 YMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVD 729 +M TP++N Y+ S+ + A Q L++ G+ADDNVH Q + ++ALV + Sbjct: 633 FM--RTPKENASGYKMSSALDVASQL-QGNLLIVSGSADDNVHLQNTMLFTEALVQANIP 689 Query: 730 FQAMWYTDEDHGIASSTAHQHIYTHMSHFI 759 F Y D++H I H+YT + F+ Sbjct: 690 FDMAIYMDKNHSIYGGNTRYHLYTRKAKFL 719 >5YP1-A nrPDB Length = 745 Score = 629 bits (1623), Expect = 0.0, Method: Composition-based stats. Identities = 175/679 (25%), Positives = 288/679 (42%), Gaps = 61/679 (8%) Query: 101 SINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVT---W 157 I DY SPDG+ +L YDL K ++ N + T Sbjct: 112 GIVDYQWSPDGKALLFPLG----------GELYFYDLTKSGRDAVRKLTNGGGFATDPKI 161 Query: 158 SPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWS 217 SP G ++++ + +++ + ++T G D I NG+ ++V +EE+ ++ WW+ Sbjct: 162 SPKGGFVSFIRDRNLWAIDLASGKEVQLTRDGS-DTIGNGVAEFVADEEM-DRHTGYWWA 219 Query: 218 PNGTFLAYAQFNDTEVPLIE-YSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL 276 P+ +A+A+ ++T VP+ + Y Y D + + V YP AG N V+ V+ + Sbjct: 220 PDDAAIAFARIDETPVPVQKRYEVYPDRT----EVVEQRYPAAGDHNVRVQLGVIAPKTG 275 Query: 277 SSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGR 336 + I D YL V W +R++ Q R+ ++ +++ + ++G Sbjct: 276 ARP-----RWIDLGKD---PDIYLARVDWRDPQRLTFQ--RQSRDQKKIELIETTLTNGT 325 Query: 337 WNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTF 396 LV ++T WV ++ F DG + S G+ H+ D T Sbjct: 326 QRTLVT-----ETSTTWVPLH--NDLRFLKDGRFLWS--SERSGFEHLYVASEDGSTLTA 376 Query: 397 ITKGTWEVIGIEAL-TSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQ 455 +T+G W V + A+ + L Y+S G ++Y + LS Sbjct: 377 LTQGEWVVDSLLAIDEAAGLAYVSGTRDGATEA-HVYAVPLSGGEPRRLTQAPG------ 429 Query: 456 YYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVL-----EDNSALDKMLQNVQMP 510 ++ +F++ A + S + L L D + + P Sbjct: 430 MHAATFARNASVFVDSWSSDTTLPQIELFKADGTKLATLLVNDVSDATHPYAKYRAAHQP 489 Query: 511 SKKLDFIILN-ETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVF----RLNWAT 565 + + T Y +I P FD K+YP+++ VY GP +Q + + Sbjct: 490 TAYGTLTAADGTTPLHYSLIKPAGFDPKKQYPVVVFVYGGPAAQTVTRAWPGRSDSFFNQ 549 Query: 566 YLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIA 625 YLA + +V + D RG+ +G A+ + GT EV+DQ+ FVD RI Sbjct: 550 YLAQ-QGYVVFTLDNRGTPRRGAAFGGALYGKQGTVEVDDQLRGIEWLKSQAFVDPARIG 608 Query: 626 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRN 685 ++GWS GGY+T M+L + CG+A APV+ W YD+ YTERYM L P+ N YR Sbjct: 609 VYGWSNGGYMTLMLLAKHDEAYACGVAGAPVTDWALYDTHYTERYMDL--PKANEAGYRE 666 Query: 686 STVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASS 745 ++V + + + LLIHG ADDNV F S ++ L G F+ M Y HG+ S Sbjct: 667 ASVFTHVDGIGAGKLLLIHGMADDNVLFTNSTKLMSELQKRGTPFELMTYPGAKHGLRGS 726 Query: 746 TAHQHIYTHMSHFIKQCFS 764 H Y F +C Sbjct: 727 DL-LHRYRLTEDFFARCLK 744 >2ECF-A nrPDB Length = 741 Score = 612 bits (1579), Expect = e-175, Method: Composition-based stats. Identities = 186/684 (27%), Positives = 292/684 (42%), Gaps = 73/684 (10%) Query: 101 SINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNK------RQLITEERIPNNTQW 154 I DY SPD Q +L +YDL + RQL E + + Sbjct: 110 GIVDYQWSPDAQRLLFPLG----------GELYLYDLKQEGKAAVRQLTHGEGFATDAKL 159 Query: 155 VTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSAL 214 SP G ++++ +++V + ++T G I NGI ++V +EE+ ++ Sbjct: 160 ---SPKGGFVSFIRGRNLWVIDLASGRQMQLTADGS-TTIGNGIAEFVADEEM-DRHTGY 214 Query: 215 WWSPNGTFLAYAQFNDTEVPLIE-YSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNT 273 WW+P+ + +AYA+ +++ VP+ + Y Y+D + + YP AG N VK V++ Sbjct: 215 WWAPDDSAIAYARIDESPVPVQKRYEVYADRT----DVIEQRYPAAGDANVQVKLGVISP 270 Query: 274 DSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDES 333 A + I D YL V W + +S Q R+ ++ +D+ + + Sbjct: 271 A-----EQAQTQWIDLGKEQ---DIYLARVNWRDPQHLSFQ--RQSRDQKKLDLVEVTLA 320 Query: 334 SGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKD 393 S + L ++ WV + F DG+ + S G++H+ K Sbjct: 321 SNQQRVLAH-----ETSPTWVPLH--NSLRFLDDGSILWS--SERTGFQHLYRIDSKGK- 370 Query: 394 CTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGR--NLYKIQLSDYTKVTCLSCELNP 451 +T G W V + A D ++ G+ R +Y + L + LS Sbjct: 371 AAALTHGNWSVDELLA--VDEKAGLAYFRAGIESARESQIYAVPLQG-GQPQRLSKAPG- 426 Query: 452 ERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDN-----SALDKMLQN 506 +S SF++ A Y S P N + + L +N + Sbjct: 427 ----MHSASFARNASVYVDSWSNNSTPPQIELFRANGEKIATLVENDLADPKHPYARYRE 482 Query: 507 VQMPSKKLDFIILNE--TKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVF----R 560 Q P + + + T Y +I P FD +K+YP+ + VY GP SQ + Sbjct: 483 AQRP-VEFGTLTAADGKTPLNYSVIKPAGFDPAKRYPVAVYVYGGPASQTVTDSWPGRGD 541 Query: 561 LNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVD 620 + YLA + +V S D RG+ +G A+ + GT EV DQ+ + +VD Sbjct: 542 HLFNQYLAQ-QGYVVFSLDNRGTPRRGRDFGGALYGKQGTVEVADQLRGVAWLKQQPWVD 600 Query: 621 NKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNL 680 RI + GWS GGY+T M+L S + CG+A APV+ W YDS YTERYM L P N Sbjct: 601 PARIGVQGWSNGGYMTLMLLAKASDSYACGVAGAPVTDWGLYDSHYTERYMDL--PARND 658 Query: 681 DHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDH 740 YR + V++ E + LLIHG ADDNV F S + AL G F+ M Y H Sbjct: 659 AGYREARVLTHIEGLRS-PLLLIHGMADDNVLFTNSTSLMSALQKRGQPFELMTYPGAKH 717 Query: 741 GIASSTAHQHIYTHMSHFIKQCFS 764 G++ + A H Y F+ +C Sbjct: 718 GLSGADA-LHRYRVAEAFLGRCLK 740 >4Q1V-A nrPDB Length = 710 Score = 589 bits (1517), Expect = e-168, Method: Composition-based stats. Identities = 173/755 (22%), Positives = 307/755 (40%), Gaps = 85/755 (11%) Query: 41 KTYTLTDYLKNT----YRLKLYSLRWISDHEYLYKQENNILVFNAEYGNSSVFLE----N 92 K TL + + Y LY L+W D E + + + + G ++ + N Sbjct: 5 KKPTLEELIPGGESYLYAENLYGLQWWGD-ECIKPGVDTLYSIQPKTGKETMVITREQIN 63 Query: 93 STFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNT 152 +E + S + + Q + + +Y+ Q+++ + + Sbjct: 64 KVLEENKAGKLSHLYS-----VRFPWTDKAQMLFTIAGKFIVYNFKNNQVVSTFKPKDGA 118 Query: 153 QWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYS 212 + +AY +N++YV + T + + I G T V+ E F Sbjct: 119 NNEDYCAASGNVAYTIDNNLYVNEKA--------VTNEPEGIVCGQT--VHRNE-FGINK 167 Query: 213 ALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVN 272 +WSP G LA+ + +++ V D + + + V YP AG + VK + N Sbjct: 168 GTFWSPKGNLLAFYRMDESMVTQY---PLVDITARVGEVNNVRYPMAGMTSHQVKVGIYN 224 Query: 273 TDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQER-ISLQWLRRIQNYSVMDICDYD 331 + SI + A D Y +++WA E+ + L + R QN++ +C Y+ Sbjct: 225 PATG------KSIYLNAGDPT---DRYFTNISWAPDEKSLYLIEVNRDQNHAK--LCQYN 273 Query: 332 ESSGR-WNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQID 390 +G L H + F P +P + + S +GY H+ F+ + Sbjct: 274 AETGEPMGVLYEEMHPKYVEPQNPIVFLPWDP-------TKFIYQSQRDGYNHLYLFETN 326 Query: 391 KKD-------------------CTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNL 431 + +TKG W V I + I +G+ G Sbjct: 327 AANMKGETYNSANGGSYFQAGKVKQLTKGNWLVSEILGFNTKRKEVIFTAVEGLRSGH-- 384 Query: 432 YKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGL 491 + + +S+ +S + +S + S Y R S P + + V+ K Sbjct: 385 FAVNVSNGK----ISQPFENCKESEHSGTLSASGTYLIDRYSTKDQP--RVINLVDTKNF 438 Query: 492 RVLEDNSALDKMLQNVQMPSKKLDFIILNE--TKFWYQMILPPHFDKSKKYPLLLDVYAG 549 + + + QMPS + I + T Y+++ P +FD +KKYP+++ VY G Sbjct: 439 KETANLLTAENPYDGYQMPSIETGTIKAADGTTDLHYRLMKPANFDPAKKYPVIVYVYGG 498 Query: 550 PCSQKADTVFR---LNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQ 606 P +Q ++ W TY+AS + I+ + D RGS +G +A RRLG E +DQ Sbjct: 499 PHAQCVTGGWQNGARGWDTYMAS-KGYIMFTIDNRGSSNRGLTFENATFRRLGIEEGKDQ 557 Query: 607 IEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVY 666 ++ + +VD++RI + GWS+GG++T+ ++ +FK G+A PV W YY+ +Y Sbjct: 558 VKGVEFLKSLPYVDSERIGVHGWSFGGHMTTALMLRYPEIFKVGVAGGPVIDWGYYEIMY 617 Query: 667 TERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDV 726 ERYM TPE N + Y+ + + A+ K L+IH DD Q + KA VD Sbjct: 618 GERYMD--TPESNPEGYKECNLKNLADQLK-GHLLIIHDDHDDTCVPQHTLSFMKACVDA 674 Query: 727 GVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 Y H +A H++ ++ + +Q Sbjct: 675 RTYPDLFIYPCHKHNVAGRD-RVHLHEKITRYFEQ 708 >2EEP-A nrPDB Length = 706 Score = 565 bits (1456), Expect = e-161, Method: Composition-based stats. Identities = 181/731 (24%), Positives = 307/731 (41%), Gaps = 86/731 (11%) Query: 60 LRWISDHEYLYKQENNILVFNAEYGNSS------------VFLENSTFDEFGHSINDYSI 107 L+W+ D+ Y++ E + LVFN G S+ + E F + ++ Sbjct: 31 LQWMGDN-YVF-IEGDDLVFNKANGKSAQTTRFSAADLNALMPEGCKFQTTDAFPSFRTL 88 Query: 108 SPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYV 167 ++L +D+ R++ T + +SPVG ++AYV Sbjct: 89 DAGRGLVVLFT----------QGGLVGFDMLARKVTYLFDTNEETASLDFSPVGDRVAYV 138 Query: 168 WNNDIYVKIEPNLPS-----YRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTF 222 N+++Y+ L +T G E ++Y V++ E F +WSP G+ Sbjct: 139 RNHNLYIARGGKLGEGMSRAIAVTIDGTETLVYG---QAVHQRE-FGIEKGTFWSPKGSC 194 Query: 223 LAYAQFNDTEV---PLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSLSSV 279 LA+ + + + V P+++Y ES + YP AG + V + + + +V Sbjct: 195 LAFYRMDQSMVKPTPIVDYHPLEAES------KPLYYPMAGTPSHHVTVGIYHLATGKTV 248 Query: 280 TNATSIQITAPASMLIGDHYLCDVTWATQER-ISLQWLRRIQNYSVMDICDYDESSGRWN 338 +Q P + +L +++W+ E + + + R QN ++ YD +GR+ Sbjct: 249 ----YLQTGEPK-----EKFLTNLSWSPDENILYVAEVNRAQNECKVNA--YDAETGRF- 296 Query: 339 CLVARQHIEMSTTGWVGRFRPSEPHFTLDG-NSFYKIISNEEGYRHICYFQIDKKDCTFI 397 R + +V P P L G N+ + S +G+ H+ + + + Sbjct: 297 ---VRTLFVETDKHYV---EPLHPLTFLPGSNNQFIWQSRRDGWNHLYLYDTTGRLIRQV 350 Query: 398 TKGTWEVIGIEAL--TSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQ 455 TKG WEV LY+ S E P R+ Y I + K L+ E R Q Sbjct: 351 TKGEWEVTNFAGFDPKGTRLYFESTE--ASPLERHFYCIDIKG-GKTKDLTPESGMHRTQ 407 Query: 456 YYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLD 515 S S +Q P +P +++ KG L + D MP + Sbjct: 408 L-SPDGSAIIDIFQ----SPTVPRKVTVTNIG-KGSHTLLEAKNPDT---GYAMPEIRTG 458 Query: 516 FIILNE--TKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLN---WATYLAST 570 I+ + T +Y++ +P HFD +KKYP+++ VY GP +Q +R + W Y+A Sbjct: 459 TIMAADGQTPLYYKLTMPLHFDPAKKYPVIVYVYGGPHAQLVTKTWRSSVGGWDIYMAQ- 517 Query: 571 ENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWS 630 + V + D RGS +G I+RRLG E+ DQ+ +VD RI + GWS Sbjct: 518 KGYAVFTVDSRGSANRGAAFEQVIHRRLGQTEMADQMCGVDFLKSQSWVDADRIGVHGWS 577 Query: 631 YGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMS 690 YGG++T+ ++ + VFK G+A PV W Y+ +Y ERY P++N + Y + ++ Sbjct: 578 YGGFMTTNLMLTHGDVFKVGVAGGPVIDWNRYEIMYGERY--FDAPQENPEGYDAANLLK 635 Query: 691 RAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQH 750 RA + K +LIHG D V +Q S A V Y +H + H Sbjct: 636 RAGDLK-GRLMLIHGAIDPVVVWQHSLLFLDACVKARTYPDYYVYPSHEHNVMGPD-RVH 693 Query: 751 IYTHMSHFIKQ 761 +Y ++ + Sbjct: 694 LYETITRYFTD 704 >6EOR-A nrPDB Length = 869 Score = 553 bits (1425), Expect = e-158, Method: Composition-based stats. Identities = 170/747 (22%), Positives = 283/747 (37%), Gaps = 85/747 (11%) Query: 88 VFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQLITEER 147 + E FG + D+ S G F+ N + R + + + ++ T + Sbjct: 127 LLRERKRLGVFGITSYDFH-SESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEIKT--Q 183 Query: 148 IPNNTQWVTWSPVG-HKLAYVWNNDIYVKIEPNLPSYRITWTGK------EDIIYNGITD 200 P +++ N+D++V R+T+ + +D G+ Sbjct: 184 CSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAGVAT 243 Query: 201 WVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYP-------KTVR 253 +V +EE F ++ WW P ++ + E E + P KT Sbjct: 244 FVIQEE-FDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKTDS 302 Query: 254 VPYPKAGAVNPTV--KFFVVNTDSLSSVTNATSIQITAPASMLIGD-HYLCDVTWATQER 310 YP+ G+ NP + K TDS + + ++ P S L Y+ W + Sbjct: 303 YRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRDGK 362 Query: 311 IS--------LQWLRRIQNYSVMDICDYDESSGRWNCLVARQH-------IEMSTTGWVG 355 + QWL+ + + I + R A E T W+ Sbjct: 363 YAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVWIN 422 Query: 356 R---FRPSEPHFTLDGNSFYKIISNEEGYRHICY----------------------FQID 390 F P D F + + G+ H+ F+ Sbjct: 423 VHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFKCP 482 Query: 391 KKDCTFITKGTWEVI-----GIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCL 445 K+ +T G WEV+ I L Y K P +LY + ++ L Sbjct: 483 IKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGT-KDTPLEHHLYVVSYEAAGEIVRL 541 Query: 446 SCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQ 505 + C S +F +Y + P + +Y L +D + + M++ Sbjct: 542 TTPGFSHSCSM-SQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDP---LHKQPRFWASMME 597 Query: 506 NVQ-----MPSKKLDFIILNETKFWYQMILPPH-FDKSKKYPLLLDVYAGPCSQKADTVF 559 +P + F ++ + Y MI PH KK+P +L VY GP Q + F Sbjct: 598 AASCPPDYVPPEIFHFHTRSDVRL-YGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSF 656 Query: 560 RLNWATYLASTE--NIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSK-M 616 + L + V DGRGS +G + A+ ++G E+EDQ+E + ++ Sbjct: 657 KGIKYLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKY 716 Query: 617 GFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTP 676 GF+D R+AI GWSYGG+++ M L VFK IA APV+ W YD+ YTERYM + P Sbjct: 717 GFIDLSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDV--P 774 Query: 677 EDNLDHYRNSTVMSRAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMW 734 E+N Y +V E + L++HG D+NVHF + + L+ G +Q Sbjct: 775 ENNQHGYEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQI 834 Query: 735 YTDEDHGIASSTAHQHIYTHMSHFIKQ 761 Y +E H I + +H + HF+++ Sbjct: 835 YPNERHSIRCPESGEHYEVTLLHFLQE 861 >6EOT-A nrPDB Length = 898 Score = 538 bits (1386), Expect = e-153, Method: Composition-based stats. Identities = 171/673 (25%), Positives = 278/673 (41%), Gaps = 89/673 (13%) Query: 164 LAYVWNNDIYVKIEPNLPSYRITWTG------KEDIIYNGITDWVYEEEVFSAYSALWWS 217 +A++ +NDI++ R+T+ +ED G+ +V +EE F YS WW Sbjct: 228 IAFIHSNDIWISNIVTREERRLTYVHNELANMEEDARSAGVATFVLQEE-FDRYSGYWWC 286 Query: 218 PNGT---------FLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKF 268 P + Y + +++EV +I + L+ + YPK G NP V F Sbjct: 287 PKAETTPSGGKILRILYEENDESEVEIIHV---TSPMLETRRADSFRYPKTGTANPKVTF 343 Query: 269 FV--VNTDSLSSVTNATSIQITAPASMLI-GDHYLCDVTWATQERISL-QWLRRIQNY-- 322 + + D+ + + ++ P +L G Y+ W + + + L R Q Sbjct: 344 KMSEIMIDAEGRIIDVIDKELIQPFEILFEGVEYIARAGWTPEGKYAWSILLDRSQTRLQ 403 Query: 323 ----------------------------SVMDICDYDESSGRWNCL------VARQHIEM 348 SV + Y+E++ W + + H E Sbjct: 404 IVLISPELFIPVEDDVMERQRLIESVPDSVTPLIIYEETTDIWINIHDIFHVFPQSHEEE 463 Query: 349 STTGWVGRFRPSEPHF----TLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITKGTWEV 404 + + H ++ S YK S G F+ K+ IT G WEV Sbjct: 464 IEFIFASECKTGFRHLYKITSILKESKYKRSSG--GLPAPSDFKCPIKEEIAITSGEWEV 521 Query: 405 IG-----IEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSV 459 +G I+ L Y K P +LY + + +VT L+ +R +S Sbjct: 522 LGRHGSNIQVDEVRRLVYFEGT-KDSPLEHHLYVVSYVNPGEVTRLT-----DRGYSHSC 575 Query: 460 SFSKEAKYYQLRCSGPGLP----LYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLD 515 S+ ++ + S P LY L S +D + E + + + + Sbjct: 576 CISQHCDFFISKYSNQKNPHCVSLYKLSSPEDDPTCKTKEFWATILDSAGPLPDYTPPEI 635 Query: 516 FIILNETKF-WYQMILPPH-FDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTE-- 571 F + T F Y M+ PH KKYP +L +Y GP Q + F+ L + Sbjct: 636 FSFESTTGFTLYGMLYKPHDLQPGKKYPTVLFIYGGPQVQLVNNRFKGVKYFRLNTLASL 695 Query: 572 NIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQF-SKMGFVDNKRIAIWGWS 630 +V D RGS ++G K A ++G E++DQ+E + S+ F+D R+ I GWS Sbjct: 696 GYVVVVIDNRGSCHRGLKFEGAFKYKMGQIEIDDQVEGLQYLASRYDFIDLDRVGIHGWS 755 Query: 631 YGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMS 690 YGGY++ M L S +F+ IA APV+ W +YD+ YTERYMG P+ N Y +V Sbjct: 756 YGGYLSLMALMQRSDIFRVAIAGAPVTLWIFYDTGYTERYMG--HPDQNEQGYYLGSVAM 813 Query: 691 RAENF--KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAH 748 +AE F + LL+HG D+NVHF ++ + LV G + Y E H I + Sbjct: 814 QAEKFPSEPNRLLLLHGFLDENVHFAHTSILLSFLVRAGKPYDLQIYPQERHSIRVPESG 873 Query: 749 QHIYTHMSHFIKQ 761 +H H+ H++++ Sbjct: 874 EHYELHLLHYLQE 886 >5L8S-A nrPDB Length = 604 Score = 237 bits (603), Expect = 2e-62, Method: Composition-based stats. Identities = 89/489 (18%), Positives = 178/489 (36%), Gaps = 38/489 (7%) Query: 280 TNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRWNC 339 T +++ + +G+ ++ ++ S +LR N ++ E + Sbjct: 136 TRIRNLETGEDRLLNVGEVSTTELAAVSENEESFVYLRAFANTYIVGFVKMGEETFNITP 195 Query: 340 LVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCTFITK 399 + H+ M EP FT + ++ + + ++ F + K+ + + Sbjct: 196 DPEKVHVAM------------EPVFTDNETIYFATDYDSDEM-YLAKFDLTSKEFSKVLA 242 Query: 400 GTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSV 459 E I D + KG+ LY+ ++ C E+ Q Sbjct: 243 FDGESIQSVKWDKDNKAFYLITVKGVTD--ILYRYDVATDKVEECSLPVDIIEQIQV--- 297 Query: 460 SFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIIL 519 +K Y L +P + ++ S N + L +N L L M + Sbjct: 298 --AKSGNLYILG-RSATVP-HNVYQSSNGVEWKQLTNNRVL--GLSPEDMVEPDIVSYTS 351 Query: 520 NETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFD 579 + ++ + Y + + GP S + +FR + ++ I +F Sbjct: 352 FDGMEIEALLFKAKPENDNGY-TIFWPHGGPQSAER-KMFRSMFQCFINRGYTIFAPNF- 408 Query: 580 GRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMV 639 RGS G + G D I + GF D ++ + G SYGGY+ ++ Sbjct: 409 -RGSTGYGSAFTKLVELDWGEGPRLDCIAGIEWLFESGFTDRNKLFLVGGSYGGYMALLL 467 Query: 640 LGSGSGVFKCGIAV-APVSRWEYYDSV------YTERYMGLPTPEDNLDHYRNSTVMSRA 692 G S F+ + + P + + +SV ER++G PE + + + + ++ Sbjct: 468 HGRHSDYFRAVVDIFGPSDLFTFINSVPPHWKPIMERWLG--DPERDKERFIKDSPVTYL 525 Query: 693 ENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIY 752 + + L+I G D V ++S QI L + G D + + DE HG + +Y Sbjct: 526 DGMVK-PMLVIQGAKDPRVVKEESDQIVAKLKEKGRDVEYLVLEDEGHGFSKKENEIKVY 584 Query: 753 THMSHFIKQ 761 + M F+++ Sbjct: 585 SLMLAFLEK 593 >4HXF-B nrPDB Length = 622 Score = 228 bits (580), Expect = 1e-59, Method: Composition-based stats. Identities = 101/564 (17%), Positives = 210/564 (37%), Gaps = 52/564 (9%) Query: 217 SPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVNTDSL 276 SP+G +A+ +FN+ E + ++L K + ++ N ++ Sbjct: 67 SPDGKKIAFMRFNE-EKKTAQIWVADLKTLSAKKVLEAKNIRSIEWN-QDSRRLLAVGFK 124 Query: 277 SSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDY-DESSG 335 + PA ++ + E+ + W+ + V++ + SSG Sbjct: 125 RREDEDFIFEDDVPAWFD-------NMGFFDGEKTTF-WVIDTEGEEVIEQFEKPRFSSG 176 Query: 336 RWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDCT 395 W+ S V +F +K E+ + + ++ ID Sbjct: 177 IWHG--------DSIVVSVPHRDVIPRYFKYWDIYLWKDGEEEKLFEKVSFYAIDSDGER 228 Query: 396 FITKGTWEVIGIEALTSDYLYYISNEYKGM--PGGRNLYKIQLSDYTKVTCLSCELNPER 453 + G E D +Y E KG+ R + + ++ + L E + Sbjct: 229 ILLYGKPE--KKYVSEHDKIYIYDGEVKGILDDIDREVAQAKIRNGKVYFTLFEEGSV-N 285 Query: 454 CQYYSVSFS--KEAKYYQLRCSGPGLPLYTLHSSV--------NDKGLRVLEDNSALDKM 503 + + K++ + +Y ++ + + ++ + N + K Sbjct: 286 LYLWDGEVREIAKGKHWIMGFDADERLIYLKETATRPAELYLWDGEERQLTDYNGLIFKK 345 Query: 504 LQNVQMPSKKLDFIILN-ETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLN 562 L+ + + F ++ E WY + P + +K P+++ V+ GP K + Sbjct: 346 LKTFE--PRHFRFKSIDLELDGWY---IKPEIKEGEKAPVIVFVHGGP---KGMYGYYFK 397 Query: 563 WATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKM-GFVDN 621 + L +++ + + RGS + + R G + +D + +F ++ D Sbjct: 398 YEMQLMASKGYYIVYVNPRGSNGYSEDFALRVLERTGLEDFQDILNGIEEFLRLEPQADR 457 Query: 622 KRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW----EYYD-SVYTERYMGLPTP 676 +RI I G SYGGY+T+ L + S +FK GI+ +S W + D ++ ++ + P Sbjct: 458 ERIGITGISYGGYMTNWAL-TQSDLFKAGISENGISYWLTSYAFSDIGLWFDKEVIGDNP 516 Query: 677 EDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYT 736 +N ++YR + + A+N K LLIH D QS L D+G + + Sbjct: 517 LEN-ENYRKLSPLFYAKNVK-APLLLIHSLEDYRCPLDQSLMFYHVLKDLGKEVYIAIFK 574 Query: 737 DEDHGIASSTAHQHIYTHMSHFIK 760 HG + + +H F++ Sbjct: 575 KGAHGHSIRGSPRHRMKRYKLFME 598 >3AZQ-A nrPDB Length = 662 Score = 216 bits (550), Expect = 3e-56, Method: Composition-based stats. Identities = 61/277 (22%), Positives = 110/277 (39%), Gaps = 20/277 (7%) Query: 502 KMLQNVQMPSKKLDFIILNETKFWYQMILPPH-----FDKSKKYPLLLDVYAGPCSQKAD 556 + P ++ + + + I PPH + P ++ + GP S + Sbjct: 381 DPVDPAYYPEPQIRTFTAPDGREIHAHIYPPHSPDFTGPADELPPYVVMAHGGPTS-RVP 439 Query: 557 TVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKM 616 V L+ A + ++ I VA + GS G + R G +VED A ++ Sbjct: 440 AVLDLDVAYF--TSRGIGVADVNYGGSTGYGRAYRERLRGRWGVVDVEDCAAVATALAEE 497 Query: 617 GFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR---W-----EYYDSVYTE 668 G D R+A+ G + GG+ + L S + V+ CG + PV W ++S Y + Sbjct: 498 GTADRARLAVRGGAAGGWTAASSLVS-TDVYACGTVLYPVLDLLGWADGGTHDFESRYLD 556 Query: 669 RYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGV 728 +G + E+ + YR+ ++RA+ + V +LL+ G D +Q + +A+ GV Sbjct: 557 FLIG--SFEEFPERYRDRAPLTRADRVR-VPFLLLQGLEDPVCPPEQCDRFLEAVAGCGV 613 Query: 729 DFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFSL 765 + + E HG Q F + Sbjct: 614 PHAYLSFEGEGHGFRRKETMVRALEAELSLYAQVFGV 650 >3O4I-A nrPDB Length = 582 Score = 188 bits (477), Expect = 7e-48, Method: Composition-based stats. Identities = 58/230 (25%), Positives = 94/230 (40%), Gaps = 24/230 (10%) Query: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTE--NIIVASFDGRGSGYQGD-KIMHAINRR 597 P ++ V+ GP ++ +D+ W T+ AS V + RGS G+ + I Sbjct: 361 PTVVLVHGGPFAEDSDS-----WDTFAASLAAAGFHVVMPNYRGSTGYGEEWRLKIIGDP 415 Query: 598 LGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS 657 G E+ED AAR + G + I G+SYGGY+T L G+FK G+A A V Sbjct: 416 CG-GELEDVSAAARWARESGLASE--LYIMGYSYGGYMTLCALTMKPGLFKAGVAGASVV 472 Query: 658 RW----EYYDSV---YTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDN 710 W E D+ + E+ G + + R+ + ++ + K+ LIH Sbjct: 473 DWEEMYELSDAAFRNFIEQLTGG-----SREIMRSRSPINHVDRIKE-PLALIHPQNASR 526 Query: 711 VHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIK 760 + ++ L+ G F+A D H I + I F+ Sbjct: 527 TPLKPLLRLMGELLARGKTFEAHIIPDAGHAINTMEDAVKILLPAVFFLA 576 >6IGR-A nrPDB Length = 656 Score = 143 bits (360), Expect = 3e-34, Method: Composition-based stats. Identities = 118/704 (16%), Positives = 223/704 (31%), Gaps = 121/704 (17%) Query: 103 NDYSISPDGQFILLEYNYVKQ----------WRHSYTASYDIYDLNKRQLITEERIPNNT 152 +D +SPDG+ + + + R Y + + + + +T Sbjct: 22 SDPQVSPDGKQVAFVLAQISEEDPAKPDKDFARPRYRSGLWLSEGGAARPLTHAETGRGD 81 Query: 153 QWVTWSPVGHKLAYVWNND-----IYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEV 207 WSP G LA+V + + + + R+T NG+ Sbjct: 82 SAPRWSPDGQNLAFVRSAGEVKAALMLLPLKGGEARRVTH------FKNGV--------- 126 Query: 208 FSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVK 267 S WSP+G F+A+ DTE DE + R Y GA Sbjct: 127 ----SGPQWSPDGRFIAFTTTADTE-------DKRDERGEARVLTRPVYRANGAD----- 170 Query: 268 FFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISL--------QWLRRI 319 + ++ + + ++W R L Q + Sbjct: 171 ----WLPERPAALWLYDVEADKLREWYAPEIGIGALSWWPDSRGVLIVQSEDEWQASQWR 226 Query: 320 QNYSVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEE 379 Q+ + + D ++ ++ ++ P F L G + + Sbjct: 227 QDVYDLPLPTADA------PAAPQKLLDWNSAAHGLAPHPDGQRFALIGR-----PAGKG 275 Query: 380 GYRHICYFQIDKKDCTFITKGTWEVIGIEA---------------LTSDYLYYISNEYKG 424 H + I+ + G +G L D L + S Sbjct: 276 NTEHAHLYLIENGQHRRLDTGHDHPVGDAVGGDCHVGAFPEGPRWLDGDTLLFSSTVRGS 335 Query: 425 MPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHS 484 + L+ + K + S + E +R S P L Sbjct: 336 V----GLFTAHIGGGVKAYDHDPQG------VISAFTANEHGVALIRESATRFPEVEL-- 383 Query: 485 SVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLL 544 N + + L V+ P + L E + W ++LP +K P LL Sbjct: 384 --NGQRVTDL----HARFPF-PVREPQRVTFETELGEGEGW--VLLPEG---EQKVPALL 431 Query: 545 DVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVE 604 +++ GP + D L + V + RGS G + AI R GT + + Sbjct: 432 NIHGGPHT---DYGHGFTHEFQLMAARGYGVCYSNPRGSVGYGQAWVDAIYGRWGTVDAD 488 Query: 605 DQIEAA-RQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYD 663 D + R + +D + A+ G +YGG++T+ + G + F+ I +S + Sbjct: 489 DLLNFFDRCLEAVPRLDAAKTAVMGGAYGGFMTNWITG-HTTRFQAAITDRCISNLISFG 547 Query: 664 S------VYTERYMGLP-TPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQS 716 + + +GL + + + + + EN K L++H D +Q+ Sbjct: 548 GTSDIGLRFWDDELGLDFSRRADALKLWDLSPLQYVENVK-TPTLIVHSVLDHRCPVEQA 606 Query: 717 AQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIK 760 Q AL V + + + +E+H ++ S T ++ + Sbjct: 607 EQWYAALHKHQVPVRFVRFPEENHELSRSGRPDRRLTRLNEYFA 650 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 39/206 (18%), Positives = 70/206 (33%), Gaps = 17/206 (8%) Query: 78 VFNAEYGNSSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDL 137 ++ +E G + T E G + SPDGQ + + + A+ + L Sbjct: 61 LWLSEGGAARPL----THAETGRGDSAPRWSPDGQNLAFVRSAGEV-----KAALMLLPL 111 Query: 138 NKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRIT-----WTGKED 192 + N WSP G +A+ D K + + +T G + Sbjct: 112 KGGEARRVTHFKNGVSGPQWSPDGRFIAFTTTADTEDKRDERGEARVLTRPVYRANGADW 171 Query: 193 IIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYP-KT 251 + W+Y+ E W++P A + + D+ LI S ++ Q+ Sbjct: 172 LPERPAALWLYDVEADKLRE--WYAPEIGIGALSWWPDSRGVLIVQSEDEWQASQWRQDV 229 Query: 252 VRVPYPKAGAVNPTVKFFVVNTDSLS 277 +P P A A K N+ + Sbjct: 230 YDLPLPTADAPAAPQKLLDWNSAAHG 255 >5T88-A nrPDB Length = 616 Score = 107 bits (266), Expect = 2e-23, Method: Composition-based stats. Identities = 107/634 (16%), Positives = 198/634 (31%), Gaps = 88/634 (13%) Query: 147 RIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEE 206 RI ++S + +N D+ V + ++++ G T +EE Sbjct: 55 RITKKGIIASYSEKDRVVIKWFNGDVIVDSKELEREV------GDEVLLQGFTT---DEE 105 Query: 207 VFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTV 266 A +S G ++ +I+ P + + K G Sbjct: 106 --GEKLAYSFSIGGA-------DEGITRIIDLKTGEVIEEIKPSIWNITFLKDGYYFTRF 156 Query: 267 KFFVVNTDSLSSVTNATSIQITAPASMLIGDH----YLCDVTWATQERISLQWLRRIQNY 322 D ++ + M+ G+ Y + ++ + ++ L N Sbjct: 157 YRKEKTPDGVNPPAARMFWKDREGERMVFGEGLTSGYFMSIRKSSDGKFAIVTLTYGWNQ 216 Query: 323 SVMDICDYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLD--GNSFYKIISNEEG 380 + I D W + S P +D Y + +G Sbjct: 217 GEVYIGPIDN-----------------PQEWKKVYSASVPVEAIDVVNGKLYILTKEGKG 259 Query: 381 YRHICYFQIDKKDCTFITKGT----WEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQL 436 I + K D I +G W VI + + + L + S + + +Y + Sbjct: 260 LGKIIAIKNGKIDEV-IPEGEFPLEWAVIVRDKILAGRLVHASYKLE-------VYTLNG 311 Query: 437 SDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLED 496 ++T Y K+ + LR + +P Y L+ +D LR++E+ Sbjct: 312 EKIKEIT------FDVPGSLYP--LDKDEERVLLRYTSFTIP-YRLYEFKDD--LRLIEE 360 Query: 497 NSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKAD 556 + + DF + + I+ D+ + + + Y G Sbjct: 361 RKVEGEF-------RVEEDFATSKDGTKVHYFIVKGERDEKRAW---VFGYGGFNIALTP 410 Query: 557 TVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKM 616 +F +L I+A+ RG G++ A R +D I + K Sbjct: 411 -MFFPQVIPFLKRGGTFIMANL--RGGSEYGEEWHRAGMRENKQNVFDDFIAVLEKLKKE 467 Query: 617 GFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE-----YYDSVYTERYM 671 G+ ++A WG S GG + S L V + PV Y SV+ Y Sbjct: 468 GY----KVAAWGRSNGGLLVSATLTQRPDVMDSALIGYPVIDMLRFHKLYIGSVWIPEYG 523 Query: 672 GLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIH-GTADDNVHFQQSAQISKALVDVGVDF 730 P+D + + + K+ LI+ G DD VH + + L ++G Sbjct: 524 NPEDPKD-REFLLKYSPYHNVDPKKKYPPTLIYTGLHDDRVHPAHALKFFMKLKEIGAPV 582 Query: 731 QAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCFS 764 T H AS T + F+ + S Sbjct: 583 YLRVETKSGHMGASPETRARELTDLLAFVLKTLS 616 >4AMY-A nrPDB Length = 710 Score = 98.0 bits (242), Expect = 1e-20, Method: Composition-based stats. Identities = 53/308 (17%), Positives = 99/308 (32%), Gaps = 25/308 (8%) Query: 478 PLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKS 537 P H + + L K + + ++ + + TK ++ Sbjct: 404 PGIIYHCDLTKEELEPRVFREVTVKGIDASDYQTVQIFYPSKDGTKIPMFIVHKKGIKLD 463 Query: 538 KKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKI--MHAIN 595 +P L Y G + + ++ ++ ++ + + RG G G+ + Sbjct: 464 GSHPAFLYGYGG-FNISITPNYSVSRLIFVRHMGGVLAVA-NIRGGGEYGETWHKGGILA 521 Query: 596 RRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAP 655 + F+ D AA K G+ KR+ I G S GG + + +F C IA Sbjct: 522 NKQNCFD--DFQCAAEYLIKEGYTSPKRLTINGGSNGGLLVATCANQRPDLFGCVIAQVG 579 Query: 656 VSR---WEYYDS--VYTERYMGLPTPEDNLDHYRNSTVMSR-----AENFKQVEYLLIHG 705 V + Y +T Y G + + + + + A++ + LL+ Sbjct: 580 VMDMLKFHKYTIGHAWTTDY-GCSDSKQHFEWLIKYSPLHNVKLPEADDIQYPSMLLLTA 638 Query: 706 TADDNVHFQQSAQISKALV-------DVGVDFQAMWYTDEDHGIASSTAH-QHIYTHMSH 757 DD V S + L T HG TA + M Sbjct: 639 DHDDRVVPLHSLKFIATLQYIVGRSRKQNNPLLIHVDTKAGHGAGKPTAKVIEEVSDMFA 698 Query: 758 FIKQCFSL 765 FI +C ++ Sbjct: 699 FIARCLNI 706 >3MUN-A nrPDB Length = 693 Score = 96.8 bits (239), Expect = 3e-20, Method: Composition-based stats. Identities = 73/517 (14%), Positives = 137/517 (26%), Gaps = 63/517 (12%) Query: 278 SVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDESSGRW 337 + ++ P + D ++W E +Y D + + + Sbjct: 155 REIHLMDVESKQPLETPLKDVKFSGISWLGNEGFFYS------SYDKPDGSELSARTDQH 208 Query: 338 NCLVARQHIEMSTTGWVGRFRPSEPH------FTLDGNSFYKIISNEEGYRHICYFQIDK 391 R V P++ H T D +N + + + Sbjct: 209 KVYFHRLGTAQEDDRLVFGAIPAQHHRYVGATVTEDQRFLLISAANSTSGNRLYVKDLSQ 268 Query: 392 KDCTFIT-KGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCELN 450 ++ +T +G + Y+ P R + + Sbjct: 269 ENAPLLTVQGDLDADVSLVDNKGSTLYLLTNR-DAPNRRLVTVDAANPGPAHWRDLIPER 327 Query: 451 PERCQYYSVSFSKEAKYYQLR--------CSGPGLPLYTL-------------------- 482 + +S S A+Y G + L Sbjct: 328 QQVLTVHSGSGYLFAEYMVDATARVEQFDYEGKRVREVALPGLGSVSGFNGYWWDPALYF 387 Query: 483 --HSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIIL-------NETKFWYQMILPPH 533 + L E S + + P K D++ + T+ + Sbjct: 388 GFENYAQPPTLYRFEPKSGAISLYRASAAPFKPEDYVSEQRFYQSKDGTRVPLIISYRKG 447 Query: 534 FDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHA 593 P +L Y G F ++ A +L VA+ RG G G A Sbjct: 448 LKLDGSNPTILYGYGG-FDVSLTPSFSVSVANWLDLGGVYAVANL--RGGGEYGQAWHLA 504 Query: 594 INRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAV 653 ++ +D I AA G+ R+AI G S GG + V+ + + + Sbjct: 505 GTQQNKQNVFDDFIAAAEYLKAEGYTRTDRLAIRGGSNGGLLVGAVMTQRPDLMRVALPA 564 Query: 654 APVSRWEYYD-----SVYTERYMGLPTPEDNLDHYRNSTVMSRAE-NFKQVEYLLIHGTA 707 V Y + + Y E D+ + + + ++ Sbjct: 565 VGVLDMLRYHTFTAGTGWAYDYGTSADSEAMFDYLKGYSPLHNVRPGVSYPSTMVTTADH 624 Query: 708 DDNVHFQQSAQISKALV--DVGVDFQAM-WYTDEDHG 741 DD V S + + L + G Q + T+ HG Sbjct: 625 DDRVVPAHSFKFAATLQADNAGPHPQLIRIETNAGHG 661 >2BKL-A nrPDB Length = 695 Score = 95.3 bits (235), Expect = 8e-20, Method: Composition-based stats. Identities = 50/285 (17%), Positives = 94/285 (32%), Gaps = 18/285 (6%) Query: 466 KYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFW 525 YY +Y S L + +D + Q +++ + + TK Sbjct: 377 AYYVFTSFTTPRQIYKTSVSTGKSEL-----WAKVDVPMNPEQYQVEQVFYASKDGTKVP 431 Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGY 585 ++ + P LL Y G + + FR + +L + VA+ RG G Sbjct: 432 MFVVHRKDLKRDGNAPTLLYGYGG-FNVNMEANFRSSILPWLDAGGVYAVANL--RGGGE 488 Query: 586 QGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSG 645 G A +D AA + + KR+AI+G S GG + + Sbjct: 489 YGKAWHDAGRLDKKQNVFDDFHAAAEYLVQQKYTQPKRLAIYGGSNGGLLVGAAMTQRPE 548 Query: 646 VFKCGIAVAPVSR---WEYYDSV--YTERYMGLPTPEDNLDHYRNSTVMSRAE-NFKQVE 699 ++ + P+ + + S + Y PED + + + + Sbjct: 549 LYGAVVCAVPLLDMVRYHLFGSGRTWIPEYGTAEKPEDFKTLH-AYSPYHHVRPDVRYPA 607 Query: 700 YLLIHGTADDNVHFQQSAQISKALVDV-GVDFQAM--WYTDEDHG 741 L++ DD V + + A+ + G A+ + HG Sbjct: 608 LLMMAADHDDRVDPMHARKFVAAVQNSPGNPATALLRIEANAGHG 652 >1YR2-A nrPDB Length = 741 Score = 91.0 bits (224), Expect = 2e-18, Method: Composition-based stats. Identities = 63/318 (19%), Positives = 90/318 (28%), Gaps = 32/318 (10%) Query: 433 KIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYY-QLRCSGPGLPLYTLHSSVNDKGL 491 + L + LS SF++ A + P +H + + Sbjct: 400 AVSLPGIGSASGLSGRPGDRHAYLSFSSFTQPATVLALDPATAKTTPWEPVHLTFDPADF 459 Query: 492 RVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPC 551 RV + V PSK + TK ++ D P LL Y G Sbjct: 460 RV-----------EQVFYPSK-------DGTKVPMFIVRRK--DAKGPLPTLLYGYGGFN 499 Query: 552 SQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAAR 611 F + T++ S +A+ RG G GD A R +D I A Sbjct: 500 VALTP-WFSAGFMTWIDSGGAFALANL--RGGGEYGDAWHDAGRRDKKQNVFDDFIAAGE 556 Query: 612 QFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERY- 670 G +AI G S GG + V +F V +D RY Sbjct: 557 WLIANGVTPRHGLAIEGGSNGGLLIGAVTNQRPDLFAAASPAVGVMDMLRFDQFTAGRYW 616 Query: 671 ---MGLPTPEDNLDHYRNSTVMSRA-ENFKQVEYLLIHGTADDNVHFQQSAQISKALVDV 726 G P E + R + L+ DD V S + + AL Sbjct: 617 VDDYGYPEKEADWRVLRRYSPYHNVRSGVDYPAILVTTADTDDRVVPGHSFKYTAALQTA 676 Query: 727 G---VDFQAMWYTDEDHG 741 T HG Sbjct: 677 AIGPKPHLIRIETRAGHG 694 >3WYD-A nrPDB Length = 228 Score = 78.3 bits (191), Expect = 1e-14, Method: Composition-based stats. Identities = 44/218 (20%), Positives = 78/218 (35%), Gaps = 42/218 (19%) Query: 524 FWYQMILPPHFDKSKKYPLLLDVYA-GPCSQKADTVFRLNWATYLASTENIIVASFDGRG 582 Y++ +P +D +K +PL++ ++ G ++ A IVA GR Sbjct: 21 MPYRLYVPTTYDGTKAFPLVIALHGMGGDENSYFDSYQRGAFMIEAENRGYIVACPKGR- 79 Query: 583 SGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGS 642 + +G E D ++ + + +D RI + G S GGY T + + Sbjct: 80 ---------QPASMYVGPAER-DVMDVIAEVRRDYKIDPDRIYMTGHSMGGYGTWSIAMN 129 Query: 643 GSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLL 702 VF A+APV+ G P N + L+ Sbjct: 130 HPDVFA---ALAPVA--------------GGGNPLG-------------MANIAHIPQLV 159 Query: 703 IHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDH 740 +HG D V ++S + +A G + + + DH Sbjct: 160 VHGDNDKTVPVERSRVMVEAAKKHGTEIKYIEIPGGDH 197 >4HVT-A nrPDB Length = 711 Score = 77.9 bits (190), Expect = 2e-14, Method: Composition-based stats. Identities = 43/255 (16%), Positives = 79/255 (30%), Gaps = 13/255 (5%) Query: 520 NETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFD 579 + K Y ++ K P LL+ Y G A R+ ++ + ++A+ Sbjct: 458 DGVKIPYFLVYKKGIKFDGKNPTLLEAYGGFQVINAPYFSRIKNEVWVKNAGVSVLANI- 516 Query: 580 GRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMV 639 RG G G + + D + + K + + I G S GG + S+ Sbjct: 517 -RGGGEFGPEWHKSAQGIKRQTAFNDFFAVSEELIKQNITSPEYLGIKGGSNGGLLVSVA 575 Query: 640 LGSGSGVFKCGIAVAPVSRWEYYDS-----VYTERYMGLPTPEDNLDHYRNSTVMSRAEN 694 + +F P+ Y + Y P D L H + + Sbjct: 576 MTQRPELFGAVACEVPILDMIRYKEFGAGHSWVTEYGDPEIPND-LLHIKKYAPLENLSL 634 Query: 695 FKQVEYLLIHGT-ADDNVHFQQSAQISKALVDV-GVDFQAMWYTDEDHGIASSTAHQ--H 750 ++ +LI + D VH L + D HG + S + + Sbjct: 635 TQKYPTVLITDSVLDQRVHPWHGRIFEYVLAQNPNTKTYFLESKDSGHG-SGSDLKESAN 693 Query: 751 IYTHMSHFIKQCFSL 765 + ++ F L Sbjct: 694 YFINLYTFFANALKL 708 >5UW6-A nrPDB Length = 750 Score = 76.0 bits (185), Expect = 6e-14, Method: Composition-based stats. Identities = 39/253 (15%), Positives = 81/253 (32%), Gaps = 21/253 (8%) Query: 487 NDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDV 546 + L++ ++ D + K++ + TK + +P + Sbjct: 449 DPTQLKIFRESVVPD--FDRSEFEVKQVFVPSKDGTKIPIFIAARKGISLDGSHPCEMHG 506 Query: 547 YAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQ 606 Y G F + +L + + + RG G G++ A R +D Sbjct: 507 YGG-FGINMMPTFSASRIVFLKHLGGVFCLA-NIRGGGEYGEEWHKAGFRDKKQNVFDDF 564 Query: 607 IEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR---WEYYD 663 I AA G+ +R+AI G S GG + + + +F C A V + + Sbjct: 565 ISAAEYLISSGYTKARRVAIEGGSNGGLLVAACINQRPDLFGCAEANCGVMDMLRFHKFT 624 Query: 664 SVYTERYMGLPTPEDNLDHYR---NSTVMSRAENFKQVE---------YLLIHGTADDNV 711 Y + G D + ++ + + + +++ DD V Sbjct: 625 LGYL--WTGDYGCSDKEEEFKWLIKYSPIHNVRRPWEQPGNEETQYPATMILTADHDDRV 682 Query: 712 HFQQSAQISKALV 724 S ++ + Sbjct: 683 VPLHSFKLLATMQ 695 >5AOA-A nrPDB Length = 286 Score = 74.1 bits (180), Expect = 2e-13, Method: Composition-based stats. Identities = 38/258 (14%), Positives = 78/258 (30%), Gaps = 41/258 (15%) Query: 508 QMPSKKLDFII-LNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATY 566 +MP ++ ++ + P + + + ++ + G + FR + Sbjct: 11 EMPGAEVKVYKKVDNVDLKLYIYKPADWKPADRRSAIVFFFGGGWQSGSPAQFRPQCEYF 70 Query: 567 LASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGF---VDNKR 623 + ++ + D R K+ V D A R + VD ++ Sbjct: 71 --AGRGMVAMAADYRVGSRHNVKVADC---------VADAKSAIRWVRQHAAELGVDPQK 119 Query: 624 IAIWGWSYGGYVTSMVLG-----------SGSGVFKCGIAVAPVSRWEYYDSVYTERYMG 672 I G S GG++ + + + S I PV E Sbjct: 120 IVASGGSAGGHLAACTVMVPDLEAPEEDHTISSQANAAILFNPVLILSR------EGLKD 173 Query: 673 LPTPEDNLDHYRNS--------TVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALV 724 +D + R + ++ HGTAD+ V F+ ++A+ Sbjct: 174 HVPRQDWEERLRERLGTEPKAVSPYHHI-RAGLPPMIIFHGTADNTVPFETIRLFAEAMK 232 Query: 725 DVGVDFQAMWYTDEDHGI 742 G + + + HG Sbjct: 233 KAGNRCELVPFEGAAHGF 250 >5JRK-A nrPDB Length = 756 Score = 70.2 bits (170), Expect = 3e-12, Method: Composition-based stats. Identities = 90/587 (15%), Positives = 184/587 (31%), Gaps = 99/587 (16%) Query: 214 LWWSPNGTFLAYAQFN-DTEVPLIEYSFYSDESLQYPKTVRVPYPKAGAVNPTVKFFVVN 272 WSP+G +L Y+Q ++ P + + + + + + ++ V FF+ N Sbjct: 182 YDWSPDGKWLWYSQLRAKSDGPRVRFD--EEVTALLGR-------RRSTIDVEVDFFLRN 232 Query: 273 TDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDYDE 332 + ++ + P++ + V W E + ++ Sbjct: 233 PEGDTTRI------MARPSTDRVATRGGGRVLWRGNEVQFRIETSDGTLGGAFEFVAWNR 286 Query: 333 SSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHIC---YFQI 389 + L ++ + + + R + + G+ I ++ EG H F I Sbjct: 287 VNRTVRTLAKQRDLLSMSI--LVGPRGGQLSTSGLGSDRELIETSAEGRPHSYGRVAFDI 344 Query: 390 DKKDCTFITKGTWEVIGIEALTSDYLYYISNEYKGMPGGRNLYKIQLSDYTKVTCLSCEL 449 W+ + D + G Y + L D T V L + Sbjct: 345 GDSR-----SAGWK------RSRDGKRVVIGTRG---LGDARYGLALIDKTGVRELRADA 390 Query: 450 NPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQM 509 + RC F + G P + + + L S + ++ +Q Sbjct: 391 SLTRC-----GFDGMLRSAICVEEGMSRPPRLVRVDLGTDKITDLGPISPRHEEIEPLQ- 444 Query: 510 PSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVF-----RLNWA 564 + F+ + ++LP + ++P ++ + AD F + N+ Sbjct: 445 -TIARTFVSRDGYWSSGYVLLPRGHRAADRHPAVVVTHGT----DADDRFAEPANQWNYP 499 Query: 565 TYLASTENIIVASFDGRGSGYQGDKIMHAINRRL------------------GTFEVEDQ 606 L + +V + S Q +M A++ L G ED Sbjct: 500 VQLLAERGYVVLLLND-PSPGQSKDLMDAMHAWLRGKGPPDPETVQQKLWLTGVHSFED- 557 Query: 607 IEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAV--------APVSR 658 A + + G +D R+ I G+S G + + V + S +F+ + + Sbjct: 558 --AVTELAAEGLIDPARVGIAGYSRGSQMVN-VTVTNSKMFRAASSGDGGFLEPAGYATG 614 Query: 659 WEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQ 718 YD+VY G DN++ +R A+ + + + + Sbjct: 615 RSSYDAVY-----GGAPLSDNIERWRRFAPSLNADKVCAAVLQQVASASPSQI------E 663 Query: 719 ISKALVDVGVDFQAMWYT------DEDHGIASSTAHQHIYTHMSHFI 759 + +AL GV Q +Y DE H +T + Sbjct: 664 LFEALRAAGVATQISYYPGATAASDETHVFYLTTNRLRAMRENIAWF 710 >5TXC-A nrPDB Length = 705 Score = 69.5 bits (168), Expect = 5e-12, Method: Composition-based stats. Identities = 90/660 (13%), Positives = 181/660 (27%), Gaps = 106/660 (16%) Query: 150 NNTQWVTWSPVGHKLAY-VWNNDIYVKIEPNLPSYRITWTGKEDII---------YNGIT 199 T ++ SP G +A+ V D + + T G D I + I Sbjct: 56 ETTPLLSLSPDGRYVAFQVRQADPVTNLNVFRMVVKAT-DGATDAIDVDVGGEYLFWTIP 114 Query: 200 DWVYEEEVFSAYSALW---WSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPY 256 W Y S + WSP+GT LAY + + V + S + + + Sbjct: 115 SWGYARNAPSGANLTIQPRWSPSGTHLAYLRQDQGRVRVWRASVKGEGASPVIED----- 169 Query: 257 PKAGAVNPTVKFFVVNTDSLSSVTNATSIQITAPA--SMLIGDHYLCDVTWATQERISLQ 314 + + + + + T I P W ER Sbjct: 170 -------------AYDIEDVQWLDDNTLIYSGRPGFVEAEAEIEREGRRGWVYDERFHPL 216 Query: 315 WLRRIQNYSVMDIC--DYDESSGRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFY 372 R + + I D +G + + R +P + +F Sbjct: 217 TGARPRVLEPISIVYQVLDLKTGTRRAATPTEVARL-------REKPDPLRAMVGRTTFS 269 Query: 373 KIISNEEGYRHICYF----------QIDKKDCTFITKGTWEVIGIEALTSDYLYYISNEY 422 ++ + + D++ C IT+ + + + Y Sbjct: 270 VSRTDPQNINAPTTLVARRGEGEPVRCDEEACQNITR-------MWGDETANVLYFLRRE 322 Query: 423 KGMPGGRNLYKIQLSDYTKVTCLSCELNPERCQYYSVSFSKEAKYYQLRCSGPGLPLYTL 482 LY++ V + C+ ++AK P + Sbjct: 323 GWASNEMALYRMPADALKPVRIWHATGLLQGCE-------RQAKRLICAQESALQPRRLV 375 Query: 483 HSSVNDKGLRVLEDNSALDKMLQNVQMPSKK-LDFIILNETKFWYQMILPPHFDKSKKYP 541 ++ + L D + L ++P + L N + + ++LPP + + P Sbjct: 376 TLNLTSGQMSPLYD---PNPDLSRYRLPKVERLTLRNRNGIEVFSDLVLPPDYQLGTRLP 432 Query: 542 LLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAI------- 594 L++ Y+ + T N LA+ +++ R Sbjct: 433 LVIVQYSSRGFLRGGTG-DENPILPLATAGFAVLSFHSPRSEASYQRFTSPIAQSKAEYS 491 Query: 595 --NRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSG--------- 643 R + + + G +D R+ + G S G L + Sbjct: 492 NWRNRWNILHTLEDL--IDDLDRRGVIDPARVGLTGLSDGATTVHFGLINSHRFAAAVTS 549 Query: 644 ---SGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEY 700 + F + P S + Y D+ + ++ + A Sbjct: 550 SCCTDSFTASVMNGPRI------SGALKAYGIETDQADDGPFWAATSFVVNASRLDTP-- 601 Query: 701 LLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIK 760 LLI ++ + + AL + + Y +E H +Y + + Sbjct: 602 LLIQSADEE---YLGALPGFTALQQARKPVELIIYPNEHHVKWQPAHRLAVYNRTIDWFR 658 >2XE4-A nrPDB Length = 751 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 41/232 (17%), Positives = 67/232 (28%), Gaps = 10/232 (4%) Query: 506 NVQMPSKKLDFIILNE-TKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWA 564 + + F + TK ++ D S+ P +L Y D F + Sbjct: 474 DAANYKVERRFATAPDQTKIPLSVVYHKDLDMSQPQPCMLYGYGS-YGLSMDPQFSIQHL 532 Query: 565 TYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRI 624 Y +A G GS D I AA ++ Sbjct: 533 PYCDRGMIFAIAHIRG-GSELGRAWYEIGAKYLTKRNTFSDFIAAAEFLVNAKLTTPSQL 591 Query: 625 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR--WEYYDSVY---TERYMGLPTPEDN 679 A G S GG + VL +FK +A P D T + P + Sbjct: 592 ACEGRSAGGLLMGAVLNMRPDLFKVALAGVPFVDVMTTMCDPSIPLTTGEWEEWGNPNEY 651 Query: 680 L--DHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVD 729 D+ + + M + ++ G D V + + A+ L + D Sbjct: 652 KYYDYMLSYSPMDNVRAQEYPNIMVQCGLHDPRVAYWEPAKWVSKLRECKTD 703 >5N4B-A nrPDB Length = 731 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 51/297 (17%), Positives = 85/297 (28%), Gaps = 16/297 (5%) Query: 466 KYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALD-KMLQNVQMPSKKLDFIILNETKF 524 ++ L SG P + L S ++ + + TK Sbjct: 415 THFFLTLSGFNTPGTIARYDFTAPETQRFSILRTTKVNELDPDDFESTQVWYESKDGTKI 474 Query: 525 WYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSG 584 ++ + Y G + AD F T+L T I A RG G Sbjct: 475 PMFIVRHKSTKFDGTAAAIQYGYGG-FATSADPFFSPIILTFL-QTYGAIFAVPSIRGGG 532 Query: 585 YQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGS 644 G++ R +D I AA+ K + ++AI G + GG + + Sbjct: 533 EFGEEWHKGGRRETKVNTFDDFIAAAQFLVKNKYAAPGKVAINGAANGGLLVMGSIVRAP 592 Query: 645 -GVFKCGIAVAPVSRWEYYD-----SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV 698 G F + V+ + + Y PE+ Y + + K + Sbjct: 593 EGTFGAAVPEGGVADLLKFHKFTGGQAWISEYGNPSIPEEFDYIY-PLSPVHNVRTDKVM 651 Query: 699 EYLLIH-GTADDNVHFQQSAQISKALVDV--GVDFQAMWYTDE---DHGIASSTAHQ 749 LI D V S + L + D+ HG+ T Sbjct: 652 PATLITVNIGDGRVVPMHSFKFIATLQHNVPQNPHPLLIKIDKSWLGHGMGKPTDKN 708 >4BP8-A nrPDB Length = 715 Score = 67.9 bits (164), Expect = 2e-11, Method: Composition-based stats. Identities = 42/256 (16%), Positives = 77/256 (30%), Gaps = 16/256 (6%) Query: 520 NETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFD 579 + TK ++ D K P +L Y + F + Y+ +A Sbjct: 455 DGTKVPISLVYDTSIDLKKPNPTMLYGYGS-YGICIEPEFNSRFLPYVDRGMIYAIAHVR 513 Query: 580 GRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMV 639 G G + D I A G +++ G S GG + V Sbjct: 514 GGGEMGR-TWYEVGGKYLTKRNTFMDFIACAEHLISSGLTTPAQLSCEGRSAGGLLVGAV 572 Query: 640 LGSGSGVFKCGIAVAPVSRWE---------YYDSVYTERYMGLPTPEDNLDHYRNSTVMS 690 L +F +A P + E G P D+ + + + Sbjct: 573 LNMRPDLFHVALAGVPFVDVMTTMCDPSIPLTTGEWEE--WGNPNEYKFFDYMNSYSPID 630 Query: 691 RAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDF-QAMWYTDEDHGIASSTAHQ 749 ++ G D V + + A+ + L ++ D + + D + G S++ Sbjct: 631 NVRAQDYPHLMIQAGLHDPRVAYWEPAKWASKLRELKTDSNEVLLKMDLESGHFSASDRY 690 Query: 750 HIYTHMSHFIKQCFSL 765 + I+Q F L Sbjct: 691 KYLR--ENAIQQAFVL 704 >4Q3K-A nrPDB Length = 260 Score = 61.0 bits (146), Expect = 2e-09, Method: Composition-based stats. Identities = 37/209 (17%), Positives = 67/209 (32%), Gaps = 32/209 (15%) Query: 539 KYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRL 598 K P +L G +D +YLA N V + + HA+ R Sbjct: 53 KRPAMLIFPGGGYQFCSDREAEPIALSYLAKGYNAFVLRYSVK---------EHAVFPR- 102 Query: 599 GTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 658 + ED + + + ++ +IA+ G+S GG++ + + G + P Sbjct: 103 PLIDAEDALSYLKDNAHALHINPDKIAVIGFSAGGHLATTLATEGKVRPNAVVLGYPALI 162 Query: 659 WEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQ 718 E+Y PTP+ + E + H DD V Sbjct: 163 RH-------EKYWNFPTPKVDQQ---------------TPEMFVFHTFEDDLVPLSHPLY 200 Query: 719 ISKALVDVGVDFQAMWYTDEDHGIASSTA 747 I + L + + + HG++ Sbjct: 201 IVEELSKANIPVEFHLFKSGVHGLSLGNK 229 >1C7J-A nrPDB Length = 489 Score = 59.4 bits (142), Expect = 6e-09, Method: Composition-based stats. Identities = 44/311 (14%), Positives = 94/311 (30%), Gaps = 34/311 (10%) Query: 485 SVNDKGLRVLEDNSALDKMLQNVQMPSK---KLDFIILNETKFW-------YQMILPPHF 534 V + E + +L D + L+ T+ Y + P Sbjct: 33 PVGQWRFKAPEPPEVWEDVLDATAYGPVCPQPSDLLSLSYTELPRQSEDCLYVNVFAPD- 91 Query: 535 DKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQG---DKIM 591 S+ P+++ ++ G L + LA+ +IV + + R + Sbjct: 92 TPSQNLPVMVWIHGGAF-YLGAGSEPLYDGSKLAAQGEVIVVTLNYRLGPFGFMHLSSFD 150 Query: 592 HAINRRLGTFEVEDQIEAARQFSKMGFV---DNKRIAIWGWSYGGY--VTSMVLGSGSGV 646 A + LG DQ A + + D + ++G S GG + + + G+ Sbjct: 151 EAYSDNLGLL---DQAAALKWVRENISAFGGDPDNVTVFGESAGGMSIAALLAMPAAKGL 207 Query: 647 FKCGIAVAPVSRWEYYD------SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVE- 699 F+ I + SR + + + + + D L ++ A+ + E Sbjct: 208 FQKAIMESGASRTMTKEQAASTAAAFLQVLGINESQLDRLHTVAAEDLLKAADQLRIAEK 267 Query: 700 ----YLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHM 755 L D ++ + G+ DE + +S + + Sbjct: 268 ENIFQLFFQPALDPKTLPEEPEKSIAEGAASGIPLLIGTTRDEGYLFFTSDSDVRSQETL 327 Query: 756 SHFIKQCFSLP 766 ++ P Sbjct: 328 DAALEYSLGKP 338 >5V5V-A nrPDB Length = 582 Score = 58.3 bits (139), Expect = 1e-08, Method: Composition-based stats. Identities = 43/186 (23%), Positives = 75/186 (40%), Gaps = 20/186 (10%) Query: 484 SSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFD--KSKKYP 541 + N + N + D + N+ +P++ + + PP D S K P Sbjct: 83 FTDNLEAAATYVQNQSEDCLYLNLYVPTEDGPLTKKRDE----ATLNPPDTDIRDSGKKP 138 Query: 542 LLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGR-GSGYQGDKIMHAINRRLGT 600 ++L ++ G + +F + LA+ N+IVA+ + R G A G Sbjct: 139 VMLFLHGGSYMEGTGNMFD---GSVLAAYGNVIVATLNYRLGVLGFLSTGDQAAKGNYGL 195 Query: 601 FEVEDQIEAARQFSKMGF---VDNKRIAIWGWSYGGYVTSMVLGSG--SGVFKCGIA--V 653 DQI+A R S+ D +RI I+G G ++++ S G+F+ IA Sbjct: 196 L---DQIQALRWLSENIAHFGGDPERITIFGSGAGASCVNLLILSHHSEGLFQKAIAQSG 252 Query: 654 APVSRW 659 +S W Sbjct: 253 TAISSW 258 >3KSR-A nrPDB Length = 290 Score = 57.1 bits (136), Expect = 3e-08, Method: Composition-based stats. Identities = 35/234 (14%), Positives = 70/234 (29%), Gaps = 36/234 (15%) Query: 541 PLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGT 600 P +L V+ SQ A I +FD RG + Sbjct: 29 PGVLFVHGWGGSQH-----HSLVRAREAVGLGCICMTFDLRGHEGYASMRQSVTRAQ--- 80 Query: 601 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRW- 659 ++D A Q + + +VD IA+ G SYGGY+++++ W Sbjct: 81 -NLDDIKAAYDQLASLPYVDAHSIAVVGLSYGGYLSALLTRERP------------VEWL 127 Query: 660 -----EYYDSVYTERYMGLPTPEDNLDHYRNSTV-------MSRAENFKQVEYLLIHGTA 707 Y + ++ + +L YR + ++ +K L+ Sbjct: 128 ALRSPALYKDAHWDQPKVSLNADPDLMDYRRRALAPGDNLALAACAQYKGDVLLV--EAE 185 Query: 708 DDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 +D + + + DH ++ Q + ++ + Sbjct: 186 NDVIVPHPVMRNYADAFTNARSLTSRVIAGADHALSVKEHQQEYTRALIDWLTE 239 >3FCY-A nrPDB Length = 346 Score = 54.4 bits (129), Expect = 2e-07, Method: Composition-based stats. Identities = 45/252 (17%), Positives = 71/252 (28%), Gaps = 52/252 (20%) Query: 523 KFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRG 582 + + I P K+P L+ + S D +LN+ V + D RG Sbjct: 94 RIHAKYIKPKT---EGKHPALIRFHGY-SSNSGDWNDKLNYV-----AAGFTVVAMDVRG 144 Query: 583 SGYQGDKIMHAINRRL------GTFEVED------------QIEAARQFSKMGFVDNKRI 624 G Q + L G + D Q+ M VD R+ Sbjct: 145 QGGQSQDVGGVTGNTLNGHIIRGLDDDADNMLFRHIFLDTAQLAGI--VMNMPEVDEDRV 202 Query: 625 AIWGWSYGGYVTSMVLGSGSGVFKCGIAVAP-------VSRWEYYDSVYTE--RYMGLPT 675 + G S GG ++ V K ++ P V + + Y E Y L Sbjct: 203 GVMGPSQGGGLSLACAALEPRVRKV-VSEYPFLSDYKRVWDLDLAKNAYQEITDYFRLFD 261 Query: 676 PEDNLD-------HYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGV 728 P + Y + V + A+ K + + G D + Sbjct: 262 PRHERENEVFTKLGYID--VKNLAKRIKGDVLMCV-GLMDQVCPPSTVFAAYNNIQSKK- 317 Query: 729 DFQAMWYTDEDH 740 Y D H Sbjct: 318 --DIKVYPDYGH 327 >6AAE-A nrPDB Length = 317 Score = 51.7 bits (122), Expect = 1e-06, Method: Composition-based stats. Identities = 49/287 (17%), Positives = 85/287 (29%), Gaps = 50/287 (17%) Query: 483 HSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPL 542 S N +R + DN A Q+ + I L+ ++ +P D ++ L Sbjct: 22 FSVANPAEIRAVFDNLAA-----PPQVARVENIAISLDGRDLDARLYVPE--DADERPAL 74 Query: 543 LLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFE 602 ++ + G LA V S R + Sbjct: 75 MVYYHGGGWVIGTLDTHDGTCRA-LAQKSGCAVLSIAYRLAPEYRYPA-----------P 122 Query: 603 VEDQIEAARQFSKMGF---VDNKRIAIWGWSYGGYVTS----MVLGSGSGVFKCGIAVAP 655 ED +A + VD R+A+ G S GG + + M + + + P Sbjct: 123 AEDCYDALVWAKQNAATLGVDGDRLAVGGDSAGGNLAAAVAIMARDRNGPALRHQLLIYP 182 Query: 656 VSRWEYYDSVYTE------------------RYMGLPTPEDNLDHYRNSTVMSRAENFKQ 697 V+ ++ + Y E Y+G E+ + V++ A+ Sbjct: 183 VTDNDFTLASYAENGGGEYYLSTDGMRWFWGHYLGDTAAENAP----LAAVLNVADLSGL 238 Query: 698 VEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744 +I D + +K L GV A HG S Sbjct: 239 APATVITAEYDP--LRDEGIAYAKKLDAAGVPVDAATAPGMIHGFFS 283 >5XB6-A nrPDB Length = 306 Score = 49.0 bits (115), Expect = 7e-06, Method: Composition-based stats. Identities = 24/132 (18%), Positives = 46/132 (34%), Gaps = 8/132 (6%) Query: 510 PSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLAS 569 + PP FD++++Y ++ + G ++ +A LA Sbjct: 4 NKVSFTNSNNPTISLSAVIYFPPKFDETRQYQAIVLSHPGGGVKEQTAG---TYAKKLAE 60 Query: 570 TENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGW 629 + + ++D + YQG+ ED + + +VDN RI G Sbjct: 61 -KGFVTIAYD---ASYQGESGGEPRQLENPYIRTEDISAVIDYLTTLSYVDNTRIGAMGI 116 Query: 630 SYG-GYVTSMVL 640 G GY + + Sbjct: 117 CAGAGYTANAAI 128 >6AVW-A nrPDB Length = 230 Score = 49.0 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 26/131 (19%), Positives = 42/131 (32%), Gaps = 24/131 (18%) Query: 619 VDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED 678 + + + I G S GG +T + G + S W + S ++ PE+ Sbjct: 97 TNPENVFICGLSQGGALTLASVLLYPKTLGGGAVL---SGWVPFTSSIISQF-----PEE 148 Query: 679 NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDE 738 K+ L HGT D V F+ L + GV + Y Sbjct: 149 A----------------KKTPILWSHGTDDRMVLFEAGQAALPFLKEAGVTCEFKAYPGL 192 Query: 739 DHGIASSTAHQ 749 H I++ Sbjct: 193 GHSISNKELKY 203 >3HXK-A nrPDB Length = 276 Score = 49.0 bits (115), Expect = 8e-06, Method: Composition-based stats. Identities = 38/234 (16%), Positives = 86/234 (36%), Gaps = 23/234 (9%) Query: 516 FIILNETKF--WYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENI 573 LN+T + +YQ+ P +++ +P ++ G + +LA + Sbjct: 18 TFSLNDTAWVDFYQLQNPRQ-NENYTFPAIIICPGGGYQHISQRESDPLALAFLAQGYQV 76 Query: 574 IVASFD--GRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSY 631 ++ ++ +G+ Y EV+ Q K ++ +++ + G S Sbjct: 77 LLLNYTVMNKGTNYN--------FLSQNLEEVQAVFSLIHQNHKEWQINPEQVFLLGCSA 128 Query: 632 GGYVTSMVLGSGSGVF--KCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVM 689 GG++ + G+ + K I PV+ + + + +N+ Y S + Sbjct: 129 GGHLAAW-YGNSEQIHRPKGVILCYPVTSFTF---GWPSDLSHFNFEIENISEYNISEKV 184 Query: 690 SRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIA 743 + + + H D+ V S + L V F+A ++ HG++ Sbjct: 185 TSS----TPPTFIWHTADDEGVPIYNSLKYCDRLSKHQVPFEAHFFESGPHGVS 234 >3DYV-A nrPDB Length = 251 Score = 47.9 bits (112), Expect = 2e-05, Method: Composition-based stats. Identities = 41/237 (17%), Positives = 75/237 (31%), Gaps = 32/237 (13%) Query: 542 LLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTF 601 +LL Y G + S + V F G G+ D + Sbjct: 26 VLLHAYTG-----SPNDMNFMARALQRSGYGVYVPLFSGHGTVEPLDILTKGNPDIW--- 77 Query: 602 EVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAP------ 655 + A ++ ++G S GG L + G+ G+ +P Sbjct: 78 -WAESSAAVAHM----TAKYAKVFVFGLSLGGIFAMKALETLPGITAGGVFSSPILPGKH 132 Query: 656 --VSRWEYYDSVYTERYMGLPTPEDNLDHY---------RNSTVMSRAENFKQVEYLLIH 704 V + Y Y R G + Y + +T ++ N + + Sbjct: 133 HLVPGFLKYAE-YMNRLAGKSDESTQILAYLPGQLAAIDQFATTVAADLNLVKQPTFIGQ 191 Query: 705 GTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 D+ V + + Q+ AL++ WY D H I ++AH + + F++Q Sbjct: 192 AGQDELVDGRLAYQLRDALINAAR-VDFHWYDDAKHVITVNSAHHALEEDVIAFMQQ 247 >6GI5-A nrPDB Length = 282 Score = 47.5 bits (111), Expect = 2e-05, Method: Composition-based stats. Identities = 49/272 (18%), Positives = 80/272 (29%), Gaps = 46/272 (16%) Query: 498 SALDKMLQNVQMPSKKLDFIILN--ETKFWYQMIL--PPHFDKSKKYPLLLDVYA----G 549 + +D+ L Q + + L+ + + Y++ L P + YP++ + G Sbjct: 9 ATMDRSLLQRQDLPYRFSAVDLDSVDGQRHYRLWLGRPLQAPPAAGYPVVWMLDGNAAVG 68 Query: 550 PCSQKADTVFRLNWATYLASTENIIVASFDGRG--------SGYQGDKIMHAINRRLGTF 601 + A L + D G S Q D+ G Sbjct: 69 ALDESTLRRLADGDAPLLVAIGYRTPLRIDRAGRTFDYTPASPGQADQRDPLNGLPSGGA 128 Query: 602 E-VEDQIE-AAR-QFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 658 + D + R + +D R +WG SYGG + L + G F A +P Sbjct: 129 DAFLDLLRDGMRPAVAAQAPLDTARQTLWGHSYGGLLVLHALFTRPGEFARYAAASPSLW 188 Query: 659 WEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHF----- 713 W D GL K+ E LL G+A+ Sbjct: 189 WR--DGAILGERAGLEQRLRG----------------KRAELLLWRGSAEPASPRGSLKA 230 Query: 714 ---QQSAQISKALVD-VGVDFQAMWYTDEDHG 741 Q A++ L G+ HG Sbjct: 231 EPGQAMARLVDDLRRVAGLTLDFQPLDGLGHG 262 >4V2I-A nrPDB Length = 323 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 49/301 (16%), Positives = 94/301 (31%), Gaps = 36/301 (11%) Query: 461 FSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILN 520 + + S G P + + + + + K ++ + Sbjct: 4 LEPTTQKFINALSASGGPAIYTLTPAEARDVLSGAQSGEIAKPAVDITD-----TTFAVG 58 Query: 521 ETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDG 580 T I+ P + + P+++ + DT L+ N + D Sbjct: 59 PTGATKVRIIRPQGNTDRL-PVIVYFHGA-GWVMGDTGTHDRLVRELSVRANAALVFVDY 116 Query: 581 RGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVT---- 636 S + AI + + + S+ VD R+AI G S GG +T Sbjct: 117 ERSP--EARYPVAIEQDYAVTKY------VAEHSEQLNVDPTRLAIAGDSVGGNMTAVVS 168 Query: 637 SMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTER----YMGLPTPEDNLDHYR-------- 684 + G + PV+ ++ + YTE ++ P + + Y Sbjct: 169 LLAQERGGPDITAQVLFYPVTDADFDNGSYTEFANGPWLTKPAMDWFWNQYLPEGIDRTD 228 Query: 685 -NSTVMS-RAENF-KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHG 741 T + +E Q L+I TA+++V + ++ L GVD Y H Sbjct: 229 PKITPIHATSEQLSGQAPALVI--TAENDVLRDEGEAYARKLSQAGVDVTVTRYNGTIHD 286 Query: 742 I 742 Sbjct: 287 F 287 >2HDW-A nrPDB Length = 367 Score = 47.1 bits (110), Expect = 3e-05, Method: Composition-based stats. Identities = 42/326 (12%), Positives = 86/326 (26%), Gaps = 73/326 (22%) Query: 475 PGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHF 534 P T S+ +++ + ++ +K+ F + LP + Sbjct: 32 QTSPAATTSSNTGGTNMQLQLTQEWDKTFPLSAKVEHRKVTFANRYGITLAADLYLPKNR 91 Query: 535 DKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAI 594 + +++ GP +A +A + +FD +G G + + Sbjct: 92 GGDRLPAIVI---GGPFGA-VKEQSSGLYAQTMAE-RGFVTLAFDPSYTGESGGQPRNVA 146 Query: 595 NRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAV- 653 + + T ED A S + V+ +RI + G G + + V + Sbjct: 147 SPDINT---EDFSAAVDFISLLPEVNRERIGVIGICGWGGMALNAVAVDKRVKAVVTSTM 203 Query: 654 ------------APVS--------------RWEYYDSV-------YTE-------RYMGL 673 V+ RW+ +S Y E + Sbjct: 204 YDMTRVMSKGYNDSVTLEQRTRTLEQLGQQRWKDAESGTPAYQPPYNELKGGEAQFLVDY 263 Query: 674 PTPEDNLDHYRNSTV-------------------MSRAENFKQVEYLLIHGTADDNVHFQ 714 Y V ++ + LLIHG + +F Sbjct: 264 HDYYMTPRGYHPRAVNSGNAWTMTTPLSFMNMPILTYIKEISPRPILLIHGERAHSRYFS 323 Query: 715 QSAQISKALVDVGVDFQAMWYTDEDH 740 ++ A + + H Sbjct: 324 ET-----AYAAAAEPKELLIVPGASH 344 >2WQZ-A nrPDB Length = 588 Score = 46.7 bits (109), Expect = 4e-05, Method: Composition-based stats. Identities = 32/134 (23%), Positives = 55/134 (41%), Gaps = 14/134 (10%) Query: 535 DKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGR-GSGYQGDKIMHA 593 D++ K P+++ ++ G + + + LAS N+IV + + R G A Sbjct: 130 DQNSKKPVMVYIHGGSYMEGTGNMID---GSILASYGNVIVITINYRLGILGFLSTGDQA 186 Query: 594 INRRLGTFEVEDQIEAARQFSKMGFV---DNKRIAIWGWSYGGYVTSMVLGSG--SGVFK 648 G DQI+A R + D KR+ I+G G S++ S G+F+ Sbjct: 187 AKGNYGLL---DQIQALRWIEENVGAFGGDPKRVTIFGSGAGASCVSLLTLSHYSEGLFQ 243 Query: 649 CGI--AVAPVSRWE 660 I + +S W Sbjct: 244 KAIIQSGTALSSWA 257 >2OCI-A nrPDB Length = 254 Score = 46.3 bits (108), Expect = 4e-05, Method: Composition-based stats. Identities = 37/219 (16%), Positives = 63/219 (28%), Gaps = 51/219 (23%) Query: 575 VASFDGRGSGYQ---GDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSY 631 V ++D RG G+ R D +A + F K++++ GWS Sbjct: 54 VVAWDPRGYGHSRPPDRDFPADFFER-------DAKDAVDLMKALKF---KKVSLLGWSD 103 Query: 632 GGYVTSMVLGSGSG-VFKCGIAVAPV----SRWEYYD-----SVYTERYMGLPTPEDNLD 681 GG + + K I A Y+ S ++ER P + L Sbjct: 104 GGITALIAAAKYPSYIHKMVIWGANAYVTDEDSMIYEGIRDVSKWSER---TRKPLEALY 160 Query: 682 HYR--NSTVMSRAENFKQ------------------VEYLLIHGTADDNVHFQQSAQISK 721 Y T + +Q L++HG D V + I K Sbjct: 161 GYDYFARTCEKWVDGIRQFKHLPDGNICRHLLPRVQCPALIVHGEKDPLVPRFHADFIHK 220 Query: 722 ALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIK 760 + + H + A + F++ Sbjct: 221 HVKGSR----LHLMPEGKHNLHLRFADE-FNKLAEDFLQ 254 >3BIX-A nrPDB Length = 574 Score = 46.3 bits (108), Expect = 5e-05, Method: Composition-based stats. Identities = 33/137 (24%), Positives = 56/137 (40%), Gaps = 15/137 (10%) Query: 535 DKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGR-GSGYQGDKIMHA 593 D P+++ ++ G + ++ + LAS N+IV + + R G A Sbjct: 126 DSGGPKPVMVYIHGGSYMEGTGNLYD---GSVLASYGNVIVITVNYRLGVLGFLSTGDQA 182 Query: 594 INRRLGTFEVEDQIEAARQFSK-MGFV--DNKRIAIWGWSYGGY---VTSMVLGSGSGVF 647 G D I+A R S+ +GF D RI ++G GG + ++ S G+F Sbjct: 183 AKGNYGLL---DLIQALRWTSENIGFFGGDPLRITVFGSGAGGSCVNLLTLSHYSEKGLF 239 Query: 648 KCGIA--VAPVSRWEYY 662 + IA +S W Sbjct: 240 QRAIAQSGTALSSWAVS 256 >5DWD-A nrPDB Length = 240 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 26/119 (21%), Positives = 39/119 (32%), Gaps = 10/119 (8%) Query: 650 GIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV-----EYLLIH 704 G+ A + Y GL PE S ++ E + LLIH Sbjct: 127 GLGPADTILVGFSQGAMMALYTGLRLPEPLKAIIAFSGLIVAPEKLEAEIASKPPVLLIH 186 Query: 705 GTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQCF 763 G DD V S L+D+G+D + H IA + F+++ Sbjct: 187 GDLDDVVPVIGSETALPKLIDLGIDARLHISQGSGHTIAQDGLD-----TATAFLREIL 240 >3HEA-A nrPDB Length = 271 Score = 44.8 bits (104), Expect = 1e-04, Method: Composition-based stats. Identities = 41/271 (15%), Positives = 77/271 (28%), Gaps = 73/271 (26%) Query: 543 LLDVYAGPCSQKADTVFRLNWATYL--ASTENIIVASFDGRGSGYQGDKIMHAINRRLGT 600 +L + P W + S+ +FD RG G Sbjct: 22 VLFSHGWPLDAD-------MWEYQMEYLSSRGYRTIAFDRRGFGRSDQPWTGNDYDTFA- 73 Query: 601 FEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGG-----YVTSMVLGSGSGVFKCGIA--- 652 +D + D K + + G+S GG Y+ +G+ G Sbjct: 74 ---DDIAQLIEHL------DLKEVTLVGFSMGGGDVARYIARHGSARVAGLVLLGAVTPI 124 Query: 653 ---------VAPVSRWEYYDS-VYTERYMGLPTPEDNLDHYRNSTVMSRAENFK------ 696 P+ + + + + +R + V+S+ + Sbjct: 125 FGQKPDYPQGVPLDVFARFKTELLKDRAQFISDFNAPFYGINKGQVVSQGVQTQTLQIAL 184 Query: 697 --------------------------QVEYLLIHGTADDNVHFQQSAQISKALVDVGVDF 730 V L+IHG D V F+ + +++ L+ Sbjct: 185 LASLKATVDCVTAFAETDFRPDMAKIDVPTLVIHGDGDQIVPFETTGKVAAELIKGA--- 241 Query: 731 QAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 + Y D HG A + A Q + + F+K+ Sbjct: 242 ELKVYKDAPHGFAVTHAQQ-LNEDLLAFLKR 271 >6GUD-A nrPDB Length = 292 Score = 44.4 bits (103), Expect = 2e-04, Method: Composition-based stats. Identities = 36/178 (20%), Positives = 66/178 (37%), Gaps = 21/178 (11%) Query: 502 KMLQNVQMPSKKLDFIILNETKFWY--QMILPPHFDKSKK----YPLLLDVYAGP-CSQK 554 V +P+ + F + N+ Y Q+ P H++ + P++ V Sbjct: 3 DRPTPVPLPNSE-QFYLENDRGEPYLIQVSWPLHWEDKQTGRGPLPIIYIVDGNALFLTA 61 Query: 555 ADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRL-------GTFEV---- 603 + +R A++ A I+ + +G Y + + G +V Sbjct: 62 TEAAWRRAAASHFAGGGIIVAIGYPLKGKLYDARRRSFDLTPPTACAPVGYGGADVFLDF 121 Query: 604 -EDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWE 660 E+ + A Q ++ V R A++G SYGG + L + F C IA +P W Sbjct: 122 IENSVRPAVQ-ARFPQVSLAREALYGHSYGGLLALHALFTRPQSFDCYIASSPSIWWN 178 >4B6G-A nrPDB Length = 283 Score = 44.0 bits (102), Expect = 2e-04, Method: Composition-based stats. Identities = 36/247 (14%), Positives = 88/247 (35%), Gaps = 29/247 (11%) Query: 535 DKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIV-ASFDGRGS---------- 583 + + ++ +G + + + + + Y A + I+V RG Sbjct: 45 NPENRPLGVIYWLSGLTCTEQNFITKSGFQRYAAEHQVIVVAPDTSPRGEQVPNDDAYDL 104 Query: 584 GYQGDKIMHAINRRLGT-FEVED-QIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLG 641 G ++A + +++ D + + + F N + +I G S GG+ ++ Sbjct: 105 GQSAGFYLNATEQPWAANYQMYDYILNELPRLIEKHFPTNGKRSIMGHSMGGHGALVLAL 164 Query: 642 SGSGVFKCGIAVAPV-----SRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK 696 ++ A +P+ W + +T Y+G + Y ++++ + +K Sbjct: 165 RNQERYQSVSAFSPILSPSLVPWG--EKAFTA-YLGKD--REKWQQYDANSLIQQ--GYK 217 Query: 697 QVEYLLIHGTADDNVHFQ-QSAQISKALVDVGVDFQAMWYTDEDHGIA--SSTAHQHIYT 753 + G D+ + Q ++ + ++ DH +S +HI Sbjct: 218 VQGMRIDQGLEDEFLPTQLRTEDFIETCRAANQPVDVRFHKGYDHSYYFIASFIGEHIAY 277 Query: 754 HMSHFIK 760 H + F+K Sbjct: 278 H-AAFLK 283 >3I6Y-A nrPDB Length = 280 Score = 44.0 bits (102), Expect = 3e-04, Method: Composition-based stats. Identities = 49/259 (18%), Positives = 94/259 (36%), Gaps = 37/259 (14%) Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENI--IVASFDGRGS 583 + + LPP K P+L + CS + + A LA+ I + RG Sbjct: 33 FAIYLPPQASTGAKVPVLYWLSGLTCSDE--NFMQKAGAQRLAAELGIAIVAPDTSPRGE 90 Query: 584 G---------YQGD-KIMHAINRRLGT-FEVED-QIEAARQFSKMGFVDNKRIAIWGWSY 631 G QG ++A +++ D + + + F + + AI G S Sbjct: 91 GVADDEGYDLGQGAGFYVNATQAPWNRHYQMYDYVVNELPELIESMFPVSDKRAIAGHSM 150 Query: 632 GGYVTSMVLGSGSGVFKCGIAVAPVSR-----WEYYDSVYTERYMGLPTPEDNLDHYRNS 686 GG+ + ++ A +P++ W +T Y+G T + ++ Sbjct: 151 GGHGALTIALRNPERYQSVSAFSPINNPVNCPWG--QKAFTA-YLGKDT---DTWREYDA 204 Query: 687 TVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASST 746 +++ RA + V L+ G AD+ + Q ++ +A Y E + S Sbjct: 205 SLLMRAAK-QYVPALVDQGEADNFLAEQLKPEVLEAAASSNN------YPLE---LRSHE 254 Query: 747 AHQHIYTHMSHFIKQCFSL 765 + H Y ++ FI+ Sbjct: 255 GYDHSYYFIASFIEDHLRF 273 >1THG-A nrPDB Length = 544 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 29/165 (17%), Positives = 57/165 (34%), Gaps = 20/165 (12%) Query: 498 SALDKMLQNVQMPSKKLD---------FIILNETKFWYQMILPPHFDKSKKYPLLLDVYA 548 + LDK L ++ ++ + +NE + + P K P+++ +Y Sbjct: 71 TLLDKALGLAKVIPEEFRGPLYDMAKGTVSMNEDCLYLNVFRPAGTKPDAKLPVMVWIYG 130 Query: 549 GPCSQKADTVF--RLNWATYLASTENIIVASFDGRGSGY---QGDKIMHAINRRLGTFEV 603 G + + + + ++ S + R + GD I N G + Sbjct: 131 GAFVYGSSAAYPGNSYVKESINMGQPVVFVSINYRTGPFGFLGGDAITAEGNTNAG---L 187 Query: 604 EDQIEAARQFSK--MGF-VDNKRIAIWGWSYGGYVTSMVLGSGSG 645 DQ + S F D ++ I+G S G + L + G Sbjct: 188 HDQRKGLEWVSDNIANFGGDPDKVMIFGESAGAMSVAHQLIAYGG 232 >6FKX-A nrPDB Length = 324 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 50/303 (16%), Positives = 85/303 (28%), Gaps = 48/303 (15%) Query: 473 SGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKLD-----FIILNETKFWYQ 527 P H D+GL L D +++ + + F + + Sbjct: 18 YPGRTPRPADHDEYWDRGLADLA-AVPADVVIEPAEFTTPLARCSHLWFTGTGGVRVHAK 76 Query: 528 MILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQG 587 ++ P + +P LL + ++ + Y+A VA+ D RG Sbjct: 77 LLRP--VAPVEPHPALLQFHG----YTGNSGDWSSRLHYVA--LGYTVAALDCRGQAGLS 128 Query: 588 ------DKIMHAINRRLGTFE-----------VEDQIEAARQFSKMGFVDNKRIAIWGWS 630 + A G + D A+ M VD R+A G+S Sbjct: 129 VGEAPVENWSMASYLLRGIDDDAADNLALRHLFLDTARLAQIVLAMDDVDPDRVAATGYS 188 Query: 631 YGGYVTSMVLGSGSGVFKCGIAVAP-VSRWEYYDSVYTER----YMGLPTPEDNLDHYRN 685 GG +T + + V P + + + E+ + + H R Sbjct: 189 QGGGLTLACAALEPRI-RLAAPVYPFLCDFRRAWEMDLEKGPYNEITTYFRARDPRHLRE 247 Query: 686 STVMSRAENFKQVEY--------LLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTD 737 + SR L+ AD S Q A +G Y D Sbjct: 248 EEIFSRLGYVDVQHLAPRVRAEVLMTVSLADKICPP--STQF-AAYNKLGGPKDYRLYPD 304 Query: 738 EDH 740 H Sbjct: 305 FAH 307 >1K4Y-A nrPDB Length = 534 Score = 43.6 bits (101), Expect = 3e-04, Method: Composition-based stats. Identities = 32/163 (19%), Positives = 61/163 (37%), Gaps = 14/163 (8%) Query: 503 MLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLN 562 ML + K+ + +E + + P K + P+++ ++ G + + Sbjct: 74 MLSELFTNRKENIPLKFSEDCLYLNIYTPADLTKRGRLPVMVWIHGGGLMVGGASTYD-- 131 Query: 563 WATYLASTENIIVASFDGR-GSGYQGDKIMHAINRRLGTFEVEDQIEAARQ----FSKMG 617 L++ EN++V + R G G DQ+ A R + G Sbjct: 132 -GLALSAHENVVVVTIQYRLGIWGFFSTGDEHSRGNWGHL---DQVAALRWVQDNIANFG 187 Query: 618 FVDNKRIAIWGWSYGGYVTSMVLGS--GSGVFKCGIAVAPVSR 658 D + I+G S GG S++L S +F I+ + V+ Sbjct: 188 -GDPGSVTIFGESAGGQSVSILLLSPLTKNLFHRAISESGVAL 229 >1C5K-A nrPDB Length = 439 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 27/123 (21%), Positives = 42/123 (34%), Gaps = 20/123 (16%) Query: 82 EYGNSSVFLEN------STFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIY 135 E G S++ ++ F + SPDG + S T S ++Y Sbjct: 221 ESGRSALVIQTLANGAVRQVASFPRHNGAPAFSPDGSKLAFAL--------SKTGSLNLY 272 Query: 136 --DLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNN----DIYVKIEPNLPSYRITWTG 189 DL Q+ +N TW P LA+ + +Y RITW G Sbjct: 273 VMDLASGQIRQVTDGRSNNTEPTWFPDSQNLAFTSDQAGRPQVYKVNINGGAPQRITWEG 332 Query: 190 KED 192 ++ Sbjct: 333 SQN 335 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 44/130 (33%), Gaps = 19/130 (14%) Query: 125 RHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYR 184 + Y YD + ++ R P WSP G KLAYV + S Sbjct: 178 QFPYELRVSDYDGYNQFVVH--RSPQPLMSPAWSPDGSKLAYV--------TFESGRSAL 227 Query: 185 ITWTGKEDIIYNGITDWVYEEEVFSAYSAL-WWSPNGTFLAYAQFNDTEVPLIEYSFYSD 243 + + NG V + F ++ +SP+G+ LA+A + L S Sbjct: 228 V-----IQTLANGA---VRQVASFPRHNGAPAFSPDGSKLAFALSKTGSLNLYVMDLASG 279 Query: 244 ESLQYPKTVR 253 + Q Sbjct: 280 QIRQVTDGRS 289 >3E4D-A nrPDB Length = 278 Score = 43.3 bits (100), Expect = 4e-04, Method: Composition-based stats. Identities = 29/148 (19%), Positives = 52/148 (35%), Gaps = 21/148 (14%) Query: 619 VDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVS-----RWEYYDSVYTERYMGL 673 D R +I+G S GG+ + FK A AP+ W E+Y+G Sbjct: 137 ADMSRQSIFGHSMGGHGAMTIALKNPERFKSCSAFAPIVAPSSADWSEPA---LEKYLGA 193 Query: 674 PTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAM 733 Y +++ + + E+L+ G AD + + + +A+ Sbjct: 194 D--RAAWRRYDACSLVE--DGARFPEFLIDQGKADS---------FLEKGLRPWLFEEAI 240 Query: 734 WYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 TD + + H Y +S F+ Sbjct: 241 KGTDIGLTLRMHDRYDHSYYFISTFMDD 268 >2YYS-A nrPDB Length = 286 Score = 43.3 bits (100), Expect = 5e-04, Method: Composition-based stats. Identities = 39/189 (20%), Positives = 68/189 (35%), Gaps = 26/189 (13%) Query: 512 KKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTE 571 +++ ++ + E + + + + P P L ++ GP V R YL E Sbjct: 3 EEIGYVPVGEAELYVEDVGPVEG------PALFVLHGGPGGN--AYVLREGLQDYL---E 51 Query: 572 NIIVASFDGRGSGYQGDKIMHAINRRLGTFE--VEDQIEAARQFSKMGFVDNKRIAIWGW 629 V FD RGS G + + RL T + VED + A +R + Sbjct: 52 GFRVVYFDQRGS---GRSLELPQDPRLFTVDALVEDTLLLAEALG------VERFGLLAH 102 Query: 630 SYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTER--YMGLPTPEDN-LDHYRNS 686 +G V VL + I +AP + + + E LP PE+N + + Sbjct: 103 GFGAVVALEVLRRFPQA-EGAILLAPWVNFPWLAARLAEAAGLAPLPDPEENLKEALKRE 161 Query: 687 TVMSRAENF 695 + + Sbjct: 162 EPKALFDRL 170 >3FNB-A nrPDB Length = 405 Score = 42.9 bits (99), Expect = 5e-04, Method: Composition-based stats. Identities = 51/275 (18%), Positives = 86/275 (31%), Gaps = 58/275 (21%) Query: 401 TWE--VIGIEALTSDYLYYI-SNEYKGMPG-------GRNLYKIQLSDYTKVTCLSCELN 450 W + I +++ L+YI S G P Y + K +L Sbjct: 30 NWMLGIGQIIGMSAGELFYIASGIRDGNPTDWCKRFNEHADYLEDEVERVKKVGYR-DLI 88 Query: 451 PERCQYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDK----MLQN 506 Y+S FS A + K +E+ ++K + N Sbjct: 89 SH--LYFSACFSIRAA----------------LQFTDPKDSEFMENFRRMEKLFMLAVDN 130 Query: 507 VQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVF--RLNWA 564 ++P K ++ E Y +I + K L+ V G S++ W Sbjct: 131 SKIPLKSIEVPFEGELLPGYAII-----SEDKAQDTLIVVGGGDTSREDLFYMLGYSGWE 185 Query: 565 TYLASTENIIVASFDGRG-SGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKR 623 N+++ G+G + QG D A ++ Sbjct: 186 H----DYNVLMVDLPGQGKNPNQGLHFE------------VDARAAISAILDWYQAPTEK 229 Query: 624 IAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 658 IAI G+S GGY T+ + + K IA P+ Sbjct: 230 IAIAGFSGGGYFTAQAVEKDKRI-KAWIASTPIYD 263 >4WY8-A nrPDB Length = 327 Score = 42.9 bits (99), Expect = 6e-04, Method: Composition-based stats. Identities = 42/292 (14%), Positives = 95/292 (32%), Gaps = 42/292 (14%) Query: 502 KMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRL 561 K L+ + + I I P +++ P ++ + G + R Sbjct: 43 KALEGLPDVYLEEKTINRKNGSKIELTITRPLDTENQVLPPIVFFHGGGWVVGSKLTHRR 102 Query: 562 NWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGF--- 618 ++ + S + E ++A +K Sbjct: 103 TVYELTVRARAAVIF-VNYSLSP--------EVRFPTALEE---CLDAVVWVAKEENAKS 150 Query: 619 --VDNKRIAIWGWSYGGYVTSMVLGSGSGV----FKCGIAVAPVSRWEYYDSVY------ 666 VD ++ + G S GG ++++V + K + + PV+ + Y Sbjct: 151 INVDPTKLVVAGDSAGGNLSAVVCIRAKQLGLNIIKGQVLIYPVTDDNFETDSYKQFAEN 210 Query: 667 ---TERYMG------LPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSA 717 T + M +P +D + + + ++ + + L+ D V ++ Sbjct: 211 YYLTRKLMVWFFDHYIPDKKDRQSIF-ACPLKASIDDLRVLPRALVITAEAD-VLREEGE 268 Query: 718 QISKALVDVGVDFQAMWYTDEDHGI----ASSTAHQHIYTHMSHFIKQCFSL 765 ++ L++ G D A+ Y HGI S I H+ ++++ + L Sbjct: 269 AYARKLIEAGNDVTAVRYLGIIHGIFNLATLSPTGSEILDHIVAWLQKTWKL 320 >1MX5-A nrPDB Length = 548 Score = 42.5 bits (98), Expect = 7e-04, Method: Composition-based stats. Identities = 30/150 (20%), Positives = 58/150 (38%), Gaps = 14/150 (9%) Query: 517 IILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVA 576 + L+E + + P K + P+++ ++ G A + + LA+ EN++V Sbjct: 92 LKLSEDCLYLNIYTPADLTKKNRLPVMVWIHGGGLMVGAASTYD---GLALAAHENVVVV 148 Query: 577 SFDGR-GSGYQGDKIMHAINRRLGTFEVEDQIEAARQ----FSKMGFVDNKRIAIWGWSY 631 + R G G DQ+ A R + G + + I+G S Sbjct: 149 TIQYRLGIWGFFSTGDEHSRGNWGHL---DQVAALRWVQDNIASFG-GNPGSVTIFGESA 204 Query: 632 GGYVTSMVLGS--GSGVFKCGIAVAPVSRW 659 GG S+++ S +F I+ + V+ Sbjct: 205 GGESVSVLVLSPLAKNLFHRAISESGVALT 234 >5FV4-A nrPDB Length = 544 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 27/140 (19%), Positives = 52/140 (37%), Gaps = 12/140 (8%) Query: 524 FWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGR-G 582 + + P K + P+++ ++ G + + LA+ EN++V + R G Sbjct: 100 LYLNIYTPADLTKRGRLPVMVWIHGGGLVVGGASTYD---GLALAAHENVVVVAIQYRLG 156 Query: 583 SGYQGDKIMHAINRRLGTFEVEDQIEAARQFSK--MGF-VDNKRIAIWGWSYGGYVTSMV 639 G DQ+ A + F D + I+G S GG S++ Sbjct: 157 IWGFFSTGDEHSRGNWGHL---DQVAALHWVQENIANFGGDPGSVTIFGESAGGESVSVL 213 Query: 640 LGS--GSGVFKCGIAVAPVS 657 + S +F I+ + V+ Sbjct: 214 VLSPLAKNLFHRAISESGVA 233 >2YH2-A nrPDB Length = 313 Score = 42.1 bits (97), Expect = 0.001, Method: Composition-based stats. Identities = 53/274 (19%), Positives = 90/274 (32%), Gaps = 47/274 (17%) Query: 495 EDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQK 554 E +S + + N + + I ++ P ++ P ++ + G Sbjct: 34 EKSSLILVKMANEPIHRVEDITIPGRGGPIRARVYRP---RDGERLPAVVYYHGGGFVLG 90 Query: 555 ADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFS 614 + + LA+ +V S D R + K A VED +AA+ + Sbjct: 91 SVET-HDHVCRRLANLSGAVVVSVDYRLAP--EHKFPAA---------VEDAYDAAKWVA 138 Query: 615 ----KMGFVDNKRIAIWGWSYGGYVTS----MVLGSGSGVFKCGIAVAPVSRWEYYDSVY 666 K+G VDN +IA+ G S GG + + M G K + + P +V Sbjct: 139 DNYDKLG-VDNGKIAVAGDSAGGNLAAVTAIMARDRGESFVKYQVLIYPAVNLTGSPTVS 197 Query: 667 TERYMG------------------LPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTAD 708 Y G P+D L Y ++ + A+ L+I D Sbjct: 198 RVEYSGPEYVILTADLMAWFGRQYFSKPQDALSPY--ASPIF-ADLSNLPPALVITAEYD 254 Query: 709 DNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGI 742 + + L GV A+ Y HG Sbjct: 255 P--LRDEGELYAHLLKTRGVRAVAVRYNGVIHGF 286 >5X6S-A nrPDB Length = 275 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 25/170 (14%), Positives = 53/170 (31%), Gaps = 5/170 (2%) Query: 551 CSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAA 610 C+ + + L+ IV SG D A G Sbjct: 40 CTGTGPGYYGDSPYATLSEQYGFIVIYPSSPYSGGCWDVSSQATLTHNGGGNSNSIANMV 99 Query: 611 RQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYY-DSVYTER 669 D+ ++ + G S G +T+++ + +F + VS +Y ++ + Sbjct: 100 TWTISKYGADSSKVFVTGSSSGAMMTNVMAATYPELFAAATVYSGVSAGCFYSNTNQVDG 159 Query: 670 YMGLPTPED---NLDHYRNSTVMSRAENFKQVEYLLI-HGTADDNVHFQQ 715 + D +H+ + + + I HG+ D ++ Q Sbjct: 160 WNSTCAQGDVITTPEHWASIAEAMYSGYSGSRPRMQIYHGSIDTTLYPQN 209 >5HFN-A nrPDB Length = 311 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 37/239 (15%), Positives = 66/239 (27%), Gaps = 32/239 (13%) Query: 536 KSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAIN 595 + +K P ++ F +W + + I D RG+ D + Sbjct: 91 EEEKLPCVVQYIG----YNGGRGFPHDWLFW--PSMGYICFVMDTRGTRGILDPRTYYYR 144 Query: 596 RRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTS--MVLGSGSGVFKCGIA- 652 R D + A + VD +RI I G S GG + L + C + Sbjct: 145 RV-----FTDAVRAVEAAASFPQVDQERIVIAGGSQGGGIALAVSALSKKAKALLCDVPF 199 Query: 653 ------VAPVSRWEYYDSVYTERYMGLPTPED----NLDHYRNSTVMSRAENFKQVEYLL 702 + Y T E+ L ++ +RA ++ L Sbjct: 200 LCHFRRAVQLVDTHPYAE-ITNFLKTHRDKEEIVFRTLSYFDGVNFAARA----KIPALF 254 Query: 703 IHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 G D+ S + G + Y +H S + ++ Sbjct: 255 SVGLMDNICPP--STVFAAYNYYAG-PKEIRIYPYNNHEGGGSFQAVEQVKFLKKLFEK 310 >1AZW-A nrPDB Length = 313 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 32/214 (14%), Positives = 63/214 (29%), Gaps = 26/214 (12%) Query: 498 SALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADT 557 L + Q S K+D + +++ PH ++ ++ GP D Sbjct: 2 RTLYPEITPYQQGSLKVD----DRHTLYFEQCGNPHGKP------VVMLHGGPGGGCNDK 51 Query: 558 VFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMG 617 + R + + FD RGSG N D + + Sbjct: 52 MRRFH------DPAKYRIVLFDQRGSGRSTPHADLVDNTTW------DLVADIERLRTHL 99 Query: 618 FVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPE 677 VD R ++G S+G + + + + + ++ + + Sbjct: 100 GVD--RWQVFGGSWGSTLALAYAQTHPQQVT-ELVLRGIFLLRRFELEWFYQEGASRLFP 156 Query: 678 DNLDHYRNS-TVMSRAENFKQVEYLLIHGTADDN 710 D +HY N+ + RA+ L Sbjct: 157 DAWEHYLNAIPPVERADLMSAFHRRLTSDDEATR 190 Score = 32.1 bits (71), Expect = 0.99, Method: Composition-based stats. Identities = 10/74 (13%), Positives = 19/74 (25%), Gaps = 4/74 (5%) Query: 685 NSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744 ++ A + +++HG D Q + + KA Q H Sbjct: 243 EDQLLRDAHRIADIPGVIVHGRYDVVCPLQSAWDLHKAWPKA----QLQISPASGHSAFE 298 Query: 745 STAHQHIYTHMSHF 758 + F Sbjct: 299 PENVDALVRATDGF 312 >2D81-A nrPDB Length = 318 Score = 41.7 bits (96), Expect = 0.001, Method: Composition-based stats. Identities = 29/131 (22%), Positives = 52/131 (39%), Gaps = 8/131 (6%) Query: 619 VDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCG---IAVAPVS--RWEYYDSVYTERYMGL 673 V+ +++ G + GGY+ + + + S VF G A P R +YY S Y + Sbjct: 8 VNPNSVSVSGLASGGYMAAQLGVAYSDVFNVGFGVFAGGPYDCARNQYYTSCMYNGYPSI 67 Query: 674 PTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKAL--VDVGVDFQ 731 TP N+ + + ++ N Q + + G++D V Q+ L D + Sbjct: 68 TTPTANMKSW-SGNQIASVANLGQRKIYMWTGSSDTTVGPNVMNQLKAQLGNFDNSANVS 126 Query: 732 AMWYTDEDHGI 742 + T H Sbjct: 127 YVTTTGAVHTF 137 >2X8B-A nrPDB Length = 583 Score = 41.3 bits (95), Expect = 0.002, Method: Composition-based stats. Identities = 26/142 (18%), Positives = 50/142 (35%), Gaps = 9/142 (6%) Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGY 585 Y + P+ + P+L+ +Y G + + +L E ++ S + R + Sbjct: 98 YLNVWTPYPRPTSPTPVLVWIYGG-GFYSGASSLDVYDGRFLVQAERTVLVSMNYRVGAF 156 Query: 586 QGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFV---DNKRIAIWGWSYGGYVTSMVLGS 642 + + G + DQ A + + D + ++G S G M L S Sbjct: 157 GFLALPGSREAP-GNVGLLDQRLALQWVQENVAAFGGDPTSVTLFGESAGAASVGMHLLS 215 Query: 643 GS--GVFKCGI--AVAPVSRWE 660 G+F + + AP W Sbjct: 216 PPSRGLFHRAVLQSGAPNGPWA 237 >4WY5-A nrPDB Length = 332 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 47/287 (16%), Positives = 102/287 (35%), Gaps = 45/287 (15%) Query: 485 SVNDKGLRVLEDNSALDKMLQNVQMPS--KKLDFIILNETKFWYQMILPPHFDKSKKYPL 542 ++ L+V+ ++S ++ N+++P ++ + + ++ PP + + P+ Sbjct: 24 PIHTLDLKVVRESSEARQLAANIKLPEVIEEDKVVESDGKTLKLTIVRPPG-TEDQILPV 82 Query: 543 LLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFE 602 L+ ++ G + L N++ D S K AI Sbjct: 83 LIFLHGGGFV-FGSKYTHIKPVRDLTVKANVVTVFVDYSLSP--EAKFPTAI-------- 131 Query: 603 VEDQIEAARQFSKMGF---VDNKRIAIWGWSYGGYVTSMVLGSG-----SGVFKCGIAVA 654 E+ A + ++ + +A+ G S G +++ V S K + + Sbjct: 132 -EEIYAAILWVRENASSLNINAEALAVAGDSAGATLSAAVSIYAKEKGLSAAIKTQVLIY 190 Query: 655 PVS--RWEYYDSV-----------------YTERYMGLPTPEDNLDHYRNSTVMSRAENF 695 P + Y+S ++ Y+ P E N D + ++A+ Sbjct: 191 PATAVSHAKYESYKLFGNGDYILSAEDLKFFSNAYLPAPASELN-DKLATLELATKADLE 249 Query: 696 KQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGI 742 LL TA+ +V + + ++ L + GVD A+ HG Sbjct: 250 GLPPALLF--TAESDVLRDEGEKYAQQLAEAGVDVAAVRVLGAVHGF 294 >3RLI-A nrPDB Length = 270 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 36/226 (15%), Positives = 62/226 (27%), Gaps = 47/226 (20%) Query: 529 ILPPHFDKSKKYPLL-----LDVYAGPCSQKADTVF-------RLNWATYLASTENIIVA 576 ++P S++YP+L GP F R Y + + + Sbjct: 14 LVPRGSHMSEQYPVLSGAEPFYAENGPVGVLLVHGFTGTPHSMRPLAEAYAKAGYTVCLP 73 Query: 577 SFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVT 636 G G+ Y + + V E + I + G S GG +T Sbjct: 74 RLKGHGTHY--EDMERTTFHDW----VASVEEGYGWLKQRCQT----IFVTGLSMGGTLT 123 Query: 637 SMVLGSGSGVFKCGIA-VAPVSRWEYYDSVYT-----ERYM-----GLPTPEDNLDHYRN 685 + + CGI + + T RY+ L P+ Y Sbjct: 124 LYLAEHHPDI--CGIVPINAAVDIPAIAAGMTGGGELPRYLDSIGSDLKNPDVKELAYEK 181 Query: 686 ---STVMSRAENFKQV---------EYLLIHGTADDNVHFQQSAQI 719 ++++ A Q L+ D V + I Sbjct: 182 TPTASLLQLARLMAQTKAKLDRIVCPALIFVSDEDHVVPPGNADII 227 >3LS2-A nrPDB Length = 280 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 46/249 (18%), Positives = 79/249 (31%), Gaps = 25/249 (10%) Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGS-- 583 + + LPP +S K P+L + C+ + + I+ RG Sbjct: 31 FAVFLPPGASESNKVPVLYWLSGLTCTDENFMQKAGAFKKAAELGIAIVAPDTSPRGDNV 90 Query: 584 --------GYQGDKIMHAINRRLGT-FEVED-QIEAARQFSKMGFVDNKRIAIWGWSYGG 633 ++A T F + D + + F AI G S GG Sbjct: 91 PNEDSYDFAQGAGFYVNATQAPYNTHFNMYDYVVNELPALIEQHFPVTSTKAISGHSMGG 150 Query: 634 YVTSMVLGSGSGVFKCGIAVAPVSR-----WEYYDSVYTERYMGLPTPEDNLDHYRNSTV 688 + M+ + A +P+ W +T Y+G + Y + + Sbjct: 151 HGALMIALKNPQDYVSASAFSPIVNPINCPWGV--KAFTG-YLGAD--KTTWAQYDSCKL 205 Query: 689 MSRAENFKQVEYLLIHGTAD---DNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASS 745 M++AE + L+ G AD D Q+ D + + D + SS Sbjct: 206 MAKAEQSNYLPMLVSQGDADNFLDEQLKPQNLVAVAKQKDYPLTLEMQTGYDHSYFFISS 265 Query: 746 TAHQHIYTH 754 QH+ H Sbjct: 266 FIDQHLVFH 274 >4BZW-A nrPDB Length = 282 Score = 40.9 bits (94), Expect = 0.002, Method: Composition-based stats. Identities = 34/228 (14%), Positives = 67/228 (29%), Gaps = 35/228 (15%) Query: 533 HFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMH 592 F+ + YP+++ G + + +A+ + +V + + Sbjct: 27 DFETAVDYPIMIICPGGGFTYHSGREEAPIATRMMAAGMHTVVLN--------YQLIVGD 78 Query: 593 AINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYV--------------TSM 638 ++ I+ + VD +RI + G+S GG+V T Sbjct: 79 QSVYPWALQQLGATIDWITTQASAHHVDCQRIILAGFSAGGHVVATYNGVATQPELRTRY 138 Query: 639 VLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFK-- 696 L G I PV G PT + + A+ Sbjct: 139 HLDHYQGQHAAIILGYPVIDLTA----------GFPTTSAARNQITTDARLWAAQRLVTP 188 Query: 697 -QVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIA 743 + D++V S + +A++ V + HG+A Sbjct: 189 ASKPAFVWQTATDESVPPINSLKYVQAMLQHQVATAYHLFGSGIHGLA 236 >1Q83-A nrPDB Length = 580 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 24/142 (16%), Positives = 49/142 (34%), Gaps = 9/142 (6%) Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGY 585 Y + P+ + P+L+ +Y G + +LA E ++ S + R + Sbjct: 129 YLNVWTPYPRPASPTPVLIWIYGG-GFYSGAASLDVYDGRFLAQVEGAVLVSMNYRVGTF 187 Query: 586 QGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFV---DNKRIAIWGWSYGGY---VTSMV 639 + + G + DQ A + + D + ++G S G + + Sbjct: 188 GFLALPGSREAP-GNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASVGMHILS 246 Query: 640 LGSGSGVFKCGI-AVAPVSRWE 660 L S S + + + P W Sbjct: 247 LPSRSLFHRAVLQSGTPNGPWA 268 >4R40-A nrPDB Length = 411 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 24/121 (19%), Positives = 41/121 (33%), Gaps = 16/121 (13%) Query: 82 EYGNSSVFLEN------STFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIY 135 E G S++ ++ F + SPDG + + S + + + Sbjct: 201 ESGKSALVIQTLANGAIRQVASFPRHNGAPAFSPDGTKLAFALS------KSGSLNLYVM 254 Query: 136 DLNKRQLITEERIPNNTQWVTWSPVGHKLAYVWNN----DIYVKIEPNLPSYRITWTGKE 191 DL Q+ +N +W P LAY + +Y RITW G + Sbjct: 255 DLASGQISQVTDGRSNNTEPSWFPDSQNLAYTSDQGGRPQVYKVNINGGVPQRITWEGSQ 314 Query: 192 D 192 + Sbjct: 315 N 315 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 25/124 (20%), Positives = 41/124 (33%), Gaps = 25/124 (20%) Query: 134 IYDLNKRQLITEERIPNNTQWVTWSPVGHKLAYVW----NNDIYVKIEPNLPSYRITWTG 189 YD + ++ R P WSP G K+AYV + + ++ N ++ Sbjct: 167 DYDGYNQFVVH--RSPEPLMSPAWSPDGSKIAYVTFESGKSALVIQTLANGAIRQVASF- 223 Query: 190 KEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYP 249 +NG + SP+GT LA+A + L S + Q Sbjct: 224 ---PRHNGAPAF---------------SPDGTKLAFALSKSGSLNLYVMDLASGQISQVT 265 Query: 250 KTVR 253 Sbjct: 266 DGRS 269 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 23/126 (18%), Positives = 41/126 (32%), Gaps = 35/126 (27%) Query: 107 ISPDGQ---FILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERIPNNTQWVTWSPVGHK 163 SPDG ++ E ++ I L + P + +SP G K Sbjct: 188 WSPDGSKIAYVTFESG---------KSALVIQTLANGAIRQVASFPRHNGAPAFSPDGTK 238 Query: 164 LAYVWNN----DIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPN 219 LA+ + ++YV + ++T G+ + + W P+ Sbjct: 239 LAFALSKSGSLNLYVMDLASGQISQVT-DGRSN------------------NTEPSWFPD 279 Query: 220 GTFLAY 225 LAY Sbjct: 280 SQNLAY 285 >2JBW-A nrPDB Length = 386 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 33/231 (14%), Positives = 80/231 (34%), Gaps = 23/231 (9%) Query: 487 NDKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDV 546 +++ + L + + P + ++++ + +P +++ Sbjct: 102 DERRQKGQARKVELYQKAAPLLSPPAERHELVVDGIPMPVYVRIPEG--PGPHPAVIML- 158 Query: 547 YAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQ 606 G S K ++ N L + A+FDG QG+ +R+ + Sbjct: 159 -GGLESTKEESFQMEN----LVLDRGMATATFDG---PGQGEMFE---YKRIAGDYEKYT 207 Query: 607 IEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYD--- 663 +K+ + N I + G S GG + C I+ S +Y+D Sbjct: 208 SAVVDLLTKLEAIRNDAIGVLGRSLGGNYALKSAACEPRLAAC-ISWGGFSDLDYWDLET 266 Query: 664 --SVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQV--EYLLIHGTADDN 710 + + +Y+ + + ++ + +R + Q+ ++HG D+ Sbjct: 267 PLTKESWKYVSKVDTLEEARLHVHAALETR-DVLSQIACPTYILHGVHDEV 316 >3RAR-A nrPDB Length = 534 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 32/176 (18%), Positives = 59/176 (33%), Gaps = 22/176 (12%) Query: 493 VLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCS 552 E+N L V +E ++ PP P++L ++ G Sbjct: 68 TYEEN-LPKAALDLVMQSKVFEAVSPSSEDCLTINVVRPPGTKAGANLPVMLWIFGGGFE 126 Query: 553 QKADTVF--RLNWATYLASTENIIVASFDGRGSGYQ---GDKIMHAINRRLGTFEVEDQI 607 + F +A + II S + R S + GD+I + G ++DQ Sbjct: 127 VGGTSTFPPAQMITKSIAMGKPIIHVSVNYRVSSWGFLAGDEIKAEGSANAG---LKDQR 183 Query: 608 EAARQFSKMGFV---DNKRIAIWGWSYGGYVTSMVLGSGSG---------VFKCGI 651 + + D ++ I+G S G ++ M + +F+ GI Sbjct: 184 LGMQWVADNIAAFGGDPTKVTIFGESAGS-MSVMCHILWNDGDNTYKGKPLFRAGI 238 >3FCX-A nrPDB Length = 282 Score = 40.6 bits (93), Expect = 0.003, Method: Composition-based stats. Identities = 24/134 (17%), Positives = 42/134 (31%), Gaps = 17/134 (12%) Query: 619 VDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR-----WEYYDSVYTERYMGL 673 VD +R++I+G S GG+ + G +K A AP+ W Y+G Sbjct: 138 VDPQRMSIFGHSMGGHGALICALKNPGKYKSVSAFAPICNPVLCPWGKKA---FSGYLGT 194 Query: 674 PTPEDNLDHYRNSTVMSRAENFKQVEY-LLIHGTADDNVHFQQSAQ---ISKALVDVGVD 729 ++ +++ + +LI DD A + + Sbjct: 195 D-----QSKWKAYDATHLVKSYPGSQLDILIDQGKDDQFLLDGQLLPDNFIAACTEKKIP 249 Query: 730 FQAMWYTDEDHGIA 743 D DH Sbjct: 250 VVFRLQEDYDHSYY 263 >2XLB-A nrPDB Length = 320 Score = 40.2 bits (92), Expect = 0.004, Method: Composition-based stats. Identities = 51/300 (17%), Positives = 91/300 (30%), Gaps = 44/300 (14%) Query: 492 RVLEDNSALDK--MLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKK--YPLLLDVY 547 + LE+ ++ L++ P K + L F + I + + +P L+ + Sbjct: 30 KSLEELRQVEAEPTLESYDYPVKGVKVYRLTYQSFGHSKIEGFYAVPDQTGPHPALVRFH 89 Query: 548 AGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDK----------------IM 591 S +NWA RG G D + Sbjct: 90 GYNASYDDGIHDIVNWA-----LHGYATFGMLVRGQGGSEDTSVTPGGHALGWMTKGILS 144 Query: 592 HAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGI 651 G + D + A VD RI + G S GG ++ + S + K + Sbjct: 145 KDTYYYRGVY--LDAVRALEVIQSFPEVDEHRIGVIGGSQGG-ALAIAAAALSDIPKVVV 201 Query: 652 AVAP-VSRWEYYDSVYTER-YMGLPT-------PEDNLDHYRNST---VMSRAENFKQVE 699 A P +S +E V E+ Y+ + + PE + + +++ A KQ Sbjct: 202 ADYPYLSNFERAVDVALEQPYLEINSYFRRNSDPEVEEKAFETLSYFDLINLAGWVKQPT 261 Query: 700 YLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFI 759 + I G D L D + Y H + + + H + Sbjct: 262 LMAI-GLIDQVTPPSTVFAAYNHLE---TDKELKVYRYFGHEFIPAFQTEKLSFLQKHLL 317 >5XKS-A nrPDB Length = 256 Score = 39.4 bits (90), Expect = 0.006, Method: Composition-based stats. Identities = 33/245 (13%), Positives = 61/245 (24%), Gaps = 46/245 (18%) Query: 543 LLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFE 602 +L ++ S ++ R Y + + G G+ Y + + + Sbjct: 23 ILVLHGFTGSPQSM---RPLGEAYHEAGYTVCGPRLKGHGTHY--EDMEKTTCQDW---- 73 Query: 603 VEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGI----------- 651 ++ I + G S GG +T + + CGI Sbjct: 74 IDSVEAGYEWLKNR----CGTIFVTGLSMGGTLTLYMAEHHPEI--CGIAPINAAINMPA 127 Query: 652 ---AVAPVSRWEYYDSVYTERYMGLPTPEDNLDHYRN------STVMSRAENFKQV---- 698 A+A V + + P Y ++ E K Sbjct: 128 LAGALAGVGDLPRFLDAIGS---DIKKPGVKELAYEKTPAASIRQIVQLMERVKTDLHKI 184 Query: 699 --EYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMS 756 +L D V + I + + + D H Q I Sbjct: 185 TCPAILFCSDEDHVVPPDNAPFIYDHIASADK--KLVRLPDSYHVATLDNDRQKIIDTSL 242 Query: 757 HFIKQ 761 F K+ Sbjct: 243 AFFKK 247 >1LLF-A nrPDB Length = 534 Score = 39.0 bits (89), Expect = 0.007, Method: Composition-based stats. Identities = 30/149 (20%), Positives = 48/149 (32%), Gaps = 37/149 (24%) Query: 528 MILPPHFDKSKKYPLLLDVYAG----------PCSQKADT-------VFRLNWATYLAST 570 ++ PP P++L ++ G P +Q + + +AS Sbjct: 102 VVRPPGTKAGANLPVMLWIFGGGFEIGSPTIFPPAQMVTKSVLMGKPIIHVAVNYRVASW 161 Query: 571 ENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWS 630 + GSG G K ++RLG V D I D ++ I+G S Sbjct: 162 GFLAGDDIKAEGSGNAGLK-----DQRLGMQWVADNIAGFG-------GDPSKVTIFGES 209 Query: 631 YGGYVTSMVLGSGSG--------VFKCGI 651 G L G +F+ GI Sbjct: 210 AGSMSVLCHLIWNDGDNTYKGKPLFRAGI 238 >5YHP-A nrPDB Length = 355 Score = 39.0 bits (89), Expect = 0.008, Method: Composition-based stats. Identities = 23/119 (19%), Positives = 45/119 (37%), Gaps = 15/119 (12%) Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGY 585 +++ + + + K ++ ++ GP +D+ R T + FD RGSG Sbjct: 58 HRLSIKEYGNPQGKP--VVFLHGGPGGGASDSDARRFNPTT------YRIVLFDQRGSG- 108 Query: 586 QGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGS 644 + VED IE R+F ++G ++G S+G + + Sbjct: 109 -ESTPASCLEDNTTQALVED-IEKIREFLQVG----AAWHVFGGSWGSTLALAYAQAHP 161 >4NOX-A nrPDB Length = 746 Score = 38.6 bits (88), Expect = 0.011, Method: Composition-based stats. Identities = 22/143 (15%), Positives = 58/143 (40%), Gaps = 4/143 (2%) Query: 93 STFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYTASYDIYDLNKRQL--ITEERIPN 150 T + F S +G ++ ++ + + + S + +I+ + ++ + + I + Sbjct: 404 RTLNLFSVSDVKMHWQSEGTYLCVKVDRHSKSKKSQATTLEIFRVKEKGVPVEVVDTIKD 463 Query: 151 NTQWVTWSPVGHKLAYVWNNDIYVKIEPNLPSYRITWTGKEDIIYNGITDWVYEEEVFSA 210 W P G + + + V P +++ E N + + + + Sbjct: 464 TVINFAWEPKGDRFVIITTPEP-VGATAVPPKTSVSFFCPELKKGNQVGSFKHLRTLEKK 522 Query: 211 -YSALWWSPNGTFLAYAQFNDTE 232 ++A++WSP G F+ A ++T+ Sbjct: 523 NHNAIYWSPKGRFVVIATVHNTQ 545 >4DGQ-A nrPDB Length = 280 Score = 38.2 bits (87), Expect = 0.014, Method: Composition-based stats. Identities = 15/44 (34%), Positives = 19/44 (43%), Gaps = 3/44 (6%) Query: 699 EYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGI 742 L+IHG D V + S +S LV G + Y HGI Sbjct: 222 PVLVIHGDDDQVVPYADSGVLSAKLVKNGK---LITYKGAPHGI 262 >2C7B-A nrPDB Length = 311 Score = 37.9 bits (86), Expect = 0.018, Method: Composition-based stats. Identities = 39/175 (22%), Positives = 65/175 (37%), Gaps = 26/175 (14%) Query: 492 RVLEDNSALDKMLQNVQMPSKKLDFIILN-ETKFWYQMILPPHFDKSKKYPLLLDVYAGP 550 R +E+ S L VQ P + + + + P K+ P +L + G Sbjct: 28 RQVEEQSRLLTA--AVQEPIAETRDVHIPVSGGSIRARVYFP--KKAAGLPAVLYYHGGG 83 Query: 551 CSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAA 610 + + L+ + +V S D R + K A VED A Sbjct: 84 FVFGSIET-HDHICRRLSRLSDSVVVSVDYRLAPEY--KFPTA---------VEDAYAAL 131 Query: 611 RQFS----KMGFVDNKRIAIWGWSYGGYVTS--MVLGSGSG--VFKCGIAVAPVS 657 + + ++G VD RIA+ G S GG + + +L SG + K + + PV Sbjct: 132 KWVADRADELG-VDPDRIAVAGDSAGGNLAAVVSILDRNSGEKLVKKQVLIYPVV 185 >1XRN-A nrPDB Length = 293 Score = 37.9 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 26/140 (18%), Positives = 44/140 (31%), Gaps = 18/140 (12%) Query: 518 ILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVAS 577 +N +Y++ P L+ ++ GP D + L + E I V Sbjct: 11 KVNGIYIYYKLCKAPEEKAK-----LMTMHGGPGMSH-DYLLSLRD----MTKEGITVLF 60 Query: 578 FDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTS 637 +D G G + G E E + N+++ + G SYGG + Sbjct: 61 YDQFGCGRSEEPDQSKFTIDYGVEEAE--------ALRSKLFGNEKVFLMGSSYGGALAL 112 Query: 638 MVLGSGSGVFKCGIAVAPVS 657 K I +S Sbjct: 113 AYAVKYQDHLKGLIVSGGLS 132 >1MPX-A nrPDB Length = 615 Score = 37.9 bits (86), Expect = 0.019, Method: Composition-based stats. Identities = 22/93 (23%), Positives = 35/93 (37%), Gaps = 5/93 (5%) Query: 571 ENIIVASFDGRGS-GYQGDKIM-HAINRRLGTFEVE---DQIEAARQFSKMGFVDNKRIA 625 I D RG G +GD +M + L EV+ D + K N ++ Sbjct: 88 GGYIRVFQDVRGKYGSEGDYVMTRPLRGPLNPSEVDHATDAWDTIDWLVKNVSESNGKVG 147 Query: 626 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 658 + G SY G+ M L + K + +P+ Sbjct: 148 MIGSSYEGFTVVMALTNPHPALKVAVPESPMID 180 >4PF1-A nrPDB Length = 626 Score = 37.5 bits (85), Expect = 0.021, Method: Composition-based stats. Identities = 24/97 (24%), Positives = 34/97 (35%), Gaps = 9/97 (9%) Query: 569 STENIIVASFDGRGSGYQGDKIMHAINRRL-------GTFEVEDQIEAARQFSKMGFVDN 621 S I+ D RG G + + +N+ L GT D + K N Sbjct: 95 SAARYIIVYQDVRGK--YGSEGGYMMNKPLTGPLNTTGTDHSTDTYDTIDWLVKNIPESN 152 Query: 622 KRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR 658 R+A G SY GY T M + K + A + Sbjct: 153 GRVAAIGGSYEGYTTLMCTINPHPALKAVVPFASMVD 189 >1LNS-A nrPDB Length = 763 Score = 37.5 bits (85), Expect = 0.026, Method: Composition-based stats. Identities = 40/241 (16%), Positives = 70/241 (29%), Gaps = 68/241 (28%) Query: 554 KADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQF 613 ++ F+ + + ++ +GR Y K H I Sbjct: 293 RSSDGFQTSGDYQQIYSMTAVIDWLNGRARAYTSRKKTHEIKASWA-------------- 338 Query: 614 SKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYY----------- 662 N ++A+ G SY G + +G + +A A +S W Y Sbjct: 339 -------NGKVAMTGKSYLGTMAYGAATTGVEGLELILAEAGISSWYNYYRENGLVRSPG 391 Query: 663 -----------DSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEY----------- 700 Y+ G + N ++ + M+ A + K +Y Sbjct: 392 GFPGEDLDVLAALTYSRNLDGADFLKGNAEYEKRLAEMTAALDRKSGDYNQFWHDRNYLI 451 Query: 701 ---------LLIHGTADDNVHFQQSAQISKALVDVGVDFQ-----AMWYTDEDHGIASST 746 L++HG D NV +Q+ KAL + A Y + I S Sbjct: 452 NTDKVKADVLIVHGLQDWNVTPEQAYNFWKALPEGHAKHAFLHRGAHIYMNSWQSIDFSE 511 Query: 747 A 747 Sbjct: 512 T 512 >2W6C-X nrPDB Length = 586 Score = 37.1 bits (84), Expect = 0.027, Method: Composition-based stats. Identities = 29/126 (23%), Positives = 48/126 (38%), Gaps = 9/126 (7%) Query: 542 LLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTF 601 +++ +Y G + + YLA TE +++ S R G G +H G Sbjct: 132 VMVWIYGG-GFYSGSSTLDVYNGKYLAYTEEVVLVSLSYR-VGAFGFLALHGSQEAPGNV 189 Query: 602 EVEDQIEAARQFSKMGFV---DNKRIAIWGWSYGGYVTSMVLGSGS--GVFKCGI--AVA 654 + DQ A + D K + I+G S GG M + S +F+ I + + Sbjct: 190 GLLDQRMALQWVHDNIQFFGGDPKTVTIFGESAGGASVGMHILSPGSRDLFRRAILQSGS 249 Query: 655 PVSRWE 660 P W Sbjct: 250 PNCPWA 255 >3EBL-A nrPDB Length = 365 Score = 37.1 bits (84), Expect = 0.033, Method: Composition-based stats. Identities = 39/252 (15%), Positives = 77/252 (30%), Gaps = 47/252 (18%) Query: 535 DKSKKYPLLLDVYAGP--CSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMH 592 ++ +P+++ + G S + T++ ++ ++ ++V S + R + Sbjct: 107 PAAEPFPVIIFFHGGSFVHSSASSTIYDSLCRRFVKLSKGVVV-SVNYRRAPEH------ 159 Query: 593 AINRRLGTFEVEDQIEAARQFSKMGFVDN-----KRIAIWGWSYGGYVT--SMVLGSGSG 645 +D A + F+ + R+ + G S GG + V + G Sbjct: 160 --RYPCA---YDDGWTALKWVMSQPFMRSGGDAQARVFLSGDSSGGNIAHHVAVRAADEG 214 Query: 646 VFKCGIAV--APVSRWEYYDSVYTERYMGLPT---------------PEDNLDHYRNSTV 688 V CG + A E +S ER + PED + Sbjct: 215 VKVCGNILLNAMFGGTERTES---ERRLDGKYFVTLQDRDWYWKAYLPEDADRDHPACNP 271 Query: 689 M----SRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIAS 744 R + L+I D Q + AL + G + + + G Sbjct: 272 FGPNGRRLGGLPFAKSLIIVSGLDLTCDRQ--LAYADALREDGHHVKVVQCENATVGFYL 329 Query: 745 STAHQHIYTHMS 756 H + M Sbjct: 330 LPNTVHYHEVME 341 >1GZ7-A nrPDB Length = 534 Score = 36.7 bits (83), Expect = 0.041, Method: Composition-based stats. Identities = 32/181 (17%), Positives = 54/181 (29%), Gaps = 37/181 (20%) Query: 496 DNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAG------ 549 +++ L V + +E +I PP S P++L ++ G Sbjct: 70 EDTLPKNALDLVLQSKIFQVVLPNDEDCLTINVIRPPGTRASAGLPVMLWIFGGGFELGG 129 Query: 550 ----PCSQKADT-------VFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRL 598 P Q V ++ +AS + GSG G + + Sbjct: 130 SSLFPGDQMVAKSVLMGKPVIHVSMNYRVASWGFLAGPDIQNEGSGNAGLH-DQRLAMQW 188 Query: 599 GTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSG--------VFKCG 650 V D I D ++ I+G S G T + L G +F+ Sbjct: 189 ----VADNIAGFG-------GDPSKVTIYGESAGSMSTFVHLVWNDGDNTYNGKPLFRAA 237 Query: 651 I 651 I Sbjct: 238 I 238 >5LZ5-A nrPDB Length = 388 Score = 36.3 bits (82), Expect = 0.046, Method: Composition-based stats. Identities = 32/185 (17%), Positives = 55/185 (29%), Gaps = 61/185 (32%) Query: 527 QMILPPH----FDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLA--STENIIVASFDG 580 M P + +KYPL++ + FR ++ ++ IVA+ + Sbjct: 82 SMTTPANWNSPLRPGEKYPLVVFSHG-------LGAFRTLYSAIGIDLASHGFIVAAVEH 134 Query: 581 RGSGYQGDKIMHA-----------INRRLGTFEVE------------------------- 604 R + R E E Sbjct: 135 RDRSASATYYFKDQSAAEIGDKSWLYLRTLKQEEETHIRNEQVRQRAKECSQALSLILDI 194 Query: 605 DQIEAARQFSKMGF--------VDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPV 656 D + + + F +D ++IA+ G S+GG L S F+CGIA+ Sbjct: 195 DHGKPVKNALDLKFDMEQLKDSIDREKIAVIGHSFGGATVIQTL-SEDQRFRCGIAL--- 250 Query: 657 SRWEY 661 W + Sbjct: 251 DAWMF 255 >1UFO-A nrPDB Length = 238 Score = 36.3 bits (82), Expect = 0.051, Method: Composition-based stats. Identities = 23/121 (19%), Positives = 45/121 (37%), Gaps = 10/121 (8%) Query: 624 IAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPED-NLDH 682 + + G S G +V ++L G F+ P + S + + ED + Sbjct: 107 LFLAGGSLGAFVAHLLLAEG---FR------PRGVLAFIGSGFPMKLPQGQVVEDPGVLA 157 Query: 683 YRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGI 742 + +R E + V L +HG+ D V + + +AL + + + +E G Sbjct: 158 LYQAPPATRGEAYGGVPLLHLHGSRDHIVPLARMEKTLEALRPHYPEGRLARFVEEGAGH 217 Query: 743 A 743 Sbjct: 218 T 218 >5L2P-A nrPDB Length = 306 Score = 36.3 bits (82), Expect = 0.052, Method: Composition-based stats. Identities = 35/182 (19%), Positives = 61/182 (33%), Gaps = 26/182 (14%) Query: 497 NSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKAD 556 N L K + + + I L + + ++ P K L++ + G + Sbjct: 35 NELLAKAVPKDPVGETRDMKIKLEDYELPIRIYSPI---KRTNNGLVMHFHGGAWILGSI 91 Query: 557 TVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFS-- 614 S E ++ S D R + K A+ D A Sbjct: 92 ETEDAISRILSNSCECTVI-SVDYRLAPEY--KFPTAVY---------DCFNAIVWARDN 139 Query: 615 --KMGFVDNKRIAIWGWSYGGYV--TSMVLGSGSGVFKCGIAVAPVSRWEYYD--SVYTE 668 ++G +D +IA +G S GG + + +L + + A PV + Y D S Sbjct: 140 AGELG-IDKDKIATFGISAGGNLVAATSLLARDNKL--KLTAQVPVVPFVYLDLASKSMN 196 Query: 669 RY 670 RY Sbjct: 197 RY 198 >5FDF-A nrPDB Length = 337 Score = 36.3 bits (82), Expect = 0.054, Method: Composition-based stats. Identities = 27/170 (15%), Positives = 47/170 (27%), Gaps = 21/170 (12%) Query: 605 DQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTS--MVLGSGSGVFKCGIA-------VAP 655 D + A + VD +RI I G S GG + L + C + Sbjct: 175 DAVRAVEAAASFPQVDQERIVIAGGSQGGGIALAVSALSKKAKALLCDVPFLCHFRRAVQ 234 Query: 656 VSRWEYYDSVYTERYMGLPTPED----NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNV 711 + Y T E+ L ++ +RA ++ L G D+ Sbjct: 235 LVDTHPYAE-ITNFLKTHRDKEEIVFRTLSYFDGVNFAARA----KIPALFSVGLMDNIC 289 Query: 712 HFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 S + G + Y +H S + ++ Sbjct: 290 PP--STVFAAYNYYAG-PKEIRIYPYNNHEGGGSFQAVEQVKFLKKLFEK 336 >4HZN-A nrPDB Length = 333 Score = 36.3 bits (82), Expect = 0.055, Method: Composition-based stats. Identities = 28/161 (17%), Positives = 50/161 (31%), Gaps = 25/161 (15%) Query: 549 GPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIE 608 GP S + W T A + + A+ D G+ + Sbjct: 39 GPGSLFVGQLGDWTWETVSAQCDTDVFAARDASGNPTYLAFYYFRVR------------- 85 Query: 609 AARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVA--PVSRWEYYD--- 663 R+ R+ + Y S++ + G A P+ E+Y+ Sbjct: 86 GGRELHPGSLTFGDRLTVTSGCYDQGTESVLTLHRID--RAGSDDAQRPLDLHEFYERPR 143 Query: 664 --SVYTE---RYMGLPTPEDNLDHYRNSTVMSRAENFKQVE 699 S+Y E R++ P N D ++S R + Q+ Sbjct: 144 DGSLYVENFNRWVTRSAPGSNEDLVKSSPPGFRNDGLPQLP 184 >3WMR-A nrPDB Length = 315 Score = 35.9 bits (81), Expect = 0.062, Method: Composition-based stats. Identities = 30/157 (19%), Positives = 57/157 (36%), Gaps = 17/157 (10%) Query: 504 LQNVQM--PSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRL 561 ++ M P + + + WY++ H S K P++L + GP S Sbjct: 12 IEGRHMSKPPSAKGTVPFGQYRTWYRVTGDLH---SGKPPVVLL-HGGPGS-----THDY 62 Query: 562 NWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDN 621 A + V +D G+G ED+++ +++G + Sbjct: 63 LLAMTSLTEAGWPVVHYDQLGNGGSTHLPEKG-EDFWTVQLFEDELDNL--LNQLGIAGD 119 Query: 622 KRIAIWGWSYGGYVTSMVLGSGS-GVFKCGIAVAPVS 657 + +G S+GG + S+ G+ +A AP S Sbjct: 120 YVL--FGQSWGGMLGSVHAARRPAGLRGLVVANAPAS 154 >3WLA-A nrPDB Length = 336 Score = 35.6 bits (80), Expect = 0.087, Method: Composition-based stats. Identities = 18/77 (23%), Positives = 29/77 (37%), Gaps = 5/77 (6%) Query: 579 DGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSM 638 DGR GDK + E + + D KR+ + G S GG +T+ Sbjct: 116 DGRAPDASGDKYKTDAGDDVRFLEAMVRCVGTKWKL-----DRKRLFLGGISAGGTMTNR 170 Query: 639 VLGSGSGVFKCGIAVAP 655 L S + G+ ++ Sbjct: 171 ALLFDSEFWAGGMPISG 187 >1NX9-A nrPDB Length = 652 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 40/196 (20%), Positives = 59/196 (30%), Gaps = 36/196 (18%) Query: 571 ENIIVASFDGRGS-GYQGDKIM----HAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIA 625 I D RG G QGD +M H T E D + N R+ Sbjct: 101 GGYIRVFQDIRGKYGSQGDYVMTRPPHGPLNPTKTDETTDAWDTVDWLVHNVPESNGRVG 160 Query: 626 IWGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSR-----------------WEYYDSVYTE 668 + G +Y G+ M L K +P+ ++Y+ S T Sbjct: 161 MTGSAYEGFTVVMALLDPHPALKVAAPESPMVDGWMGDDWFHYGAFRQGAFDYFVSQMTA 220 Query: 669 RYMGLPTPEDNLDHYRN-------STVMSRAENFKQVEY---LLIHGTADDNVHFQQSAQ 718 R G P + D Y N + ++A Q + + H D F Q Sbjct: 221 RGGGNDIPRRDADDYTNFLKAGSAGSFATQA-GLDQYPFWQRMHAHPAYDA---FWQGQA 276 Query: 719 ISKALVDVGVDFQAMW 734 + K L +W Sbjct: 277 LDKILAQRKPTVPMLW 292 >1ODT-C nrPDB Length = 318 Score = 35.2 bits (79), Expect = 0.11, Method: Composition-based stats. Identities = 57/333 (17%), Positives = 99/333 (29%), Gaps = 46/333 (13%) Query: 455 QYYSVSFSKEAKYYQLRCSGPGLPLYTLHSSVNDKGLRVLEDNSALDKMLQNVQMPSKKL 514 Q + + + Y + + + S ++ D +D V++ Sbjct: 2 QLFDLPLDQLQTYKPEKTAPKDFSEFWKLSLEELAKVQAEPDLQPVDYPADGVKVYRLTY 61 Query: 515 DFIILNETKFWYQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENII 574 WY + DK +P ++ + S + +NWA Sbjct: 62 KSFGNARITGWYAVP-----DKEGPHPAIVKYHGYNASYDGEIHEMVNWA-----LHGYA 111 Query: 575 VASFDGRGSGYQGDK----IMHAIN-RRLGTFEVE---------DQIEAARQFSKMGFVD 620 RG D HA+ G + + D + A S VD Sbjct: 112 TFGMLVRGQQSSEDTSISPHGHALGWMTKGILDKDTYYYRGVYLDAVRALEVISSFDEVD 171 Query: 621 NKRIAIWGWSYGGYVTSMVLGSGSGVFKCGIAVAP-VSRWEY-YDSVYTERYMGLPTPED 678 RI + G + GG +T + S + K +A P +S +E D E Y+ + + Sbjct: 172 ETRIGVTGGAQGGGLTIAA-AALSDIPKAAVADYPYLSNFERAIDVALEEPYLEINSFFR 230 Query: 679 NLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDE 738 RN + + + K + Y I AD +S L+D + Sbjct: 231 -----RNGSPETEVQAMKTLSYFDIMNLADRVKVP---VLMSIGLIDKVTPPST-VFAAY 281 Query: 739 DHGIASSTAHQHIY----------THMSHFIKQ 761 +H + Y T F KQ Sbjct: 282 NHLETKKELKVYRYFGHEYIPAFQTEKLAFFKQ 314 >3FM0-A nrPDB Length = 345 Score = 34.8 bits (78), Expect = 0.14, Method: Composition-based stats. Identities = 33/166 (19%), Positives = 58/166 (34%), Gaps = 36/166 (21%) Query: 73 ENNILVFNAEYGN---SSVFLENSTFDEFGHSINDYSISPDGQFILLEYNYVKQWRHSYT 129 + I ++ E + SV E ++ + SP G ++ S+ Sbjct: 37 DRRIRIWGTEGDSWICKSVLSEGH-----QRTVRKVAWSPCGNYL---------ASASFD 82 Query: 130 ASYDIYDLNKRQ---LITEERIPNNTQWVTWSPVGHKLAYV-WNNDIYVKIEPNLPSYRI 185 A+ I+ N+ + T E N + V W+P G+ LA + ++V Y Sbjct: 83 ATTCIWKKNQDDFECVTTLEGHENEVKSVAWAPSGNLLATCSRDKSVWVWEVDEEDEYEC 142 Query: 186 TWTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDT 231 + N T V + W P+ LA A ++DT Sbjct: 143 VS------VLNSHTQDV---------KHVVWHPSQELLASASYDDT 173 >6EIC-C nrPDB Length = 279 Score = 34.8 bits (78), Expect = 0.15, Method: Composition-based stats. Identities = 37/289 (12%), Positives = 90/289 (31%), Gaps = 58/289 (20%) Query: 513 KLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYA-GPCSQKADTVFRLNWATYLASTE 571 + +F + + + Y + P ++ +++ + G +++ D V + Sbjct: 7 ERNFAGIGDVRIVYDVWTPDTAPQA----VVVLAHGLGEHARRYDHVAQR------LGAA 56 Query: 572 NIIVASFDGRGSGYQGDKIMHAINRRLGTFEVE-DQIEAARQFSKMGFVDNKRIAIWGWS 630 ++ + D RG G G K + R + + + D + + KRI + G S Sbjct: 57 GLVTYALDHRGHGRSGGK--RVLVRDISEYTADFDTLVGIAT---REYPGCKRI-VLGHS 110 Query: 631 YGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDS---VYTERYMGLPTP----------- 676 GG + + + AP + S + +G+ P Sbjct: 111 MGGGIVFAYGVERPDNYDLMVLSAPAVAAQDLVSPVVAVAAKLLGVVVPGLPVQELDFTA 170 Query: 677 -EDNLDHYR--NSTVMSRAENFKQV---------------------EYLLIHGTADDNVH 712 + + + N+ + L++HGT D + Sbjct: 171 ISRDPEVVQAYNTDPLVHHGRVPAGIGRALLQVGETMPRRAPALTAPLLVLHGTDDRLIP 230 Query: 713 FQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMSHFIKQ 761 + S ++ + + D Q Y H + + + + ++ + Sbjct: 231 IEGSRRLVECV--GSADVQLKEYPGLYHEVFNEPERNQVLDDVVAWLTE 277 >5CXX-A nrPDB Length = 275 Score = 34.8 bits (78), Expect = 0.16, Method: Composition-based stats. Identities = 11/43 (25%), Positives = 22/43 (51%) Query: 506 NVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVYA 548 K + + ET+ +ILP +D++KKYP++ ++ Sbjct: 22 EYPTAKKITYYSKVTETERKMNVILPVGYDENKKYPVVYYLHG 64 >5GQY-A nrPDB Length = 793 Score = 34.0 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 18/87 (20%), Positives = 34/87 (39%), Gaps = 13/87 (14%) Query: 187 WTGKEDIIYNGITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSD--- 243 + ++ + NG D V E W+P FL+Y + + +P ++ Y+ Sbjct: 285 SSAEKMPLLNGEADPVIVSE---------WNPGARFLSYYELAEKLIPYVKDMGYTHIEL 335 Query: 244 -ESLQYPKTVRVPYPKAGAVNPTVKFF 269 ++P Y G +PT +F Sbjct: 336 LPIAEHPFDGSWGYQVTGFYSPTSRFG 362 >6BX3-A nrPDB Length = 314 Score = 34.0 bits (76), Expect = 0.22, Method: Composition-based stats. Identities = 23/104 (22%), Positives = 35/104 (33%), Gaps = 24/104 (23%) Query: 141 QLITEERIPNNTQWVT--WSPVGHKLAYVWNNDI--YVKIEPNLPSYRITWTGKEDIIYN 196 Q +T N + SP G LA +I Y + +T + Sbjct: 2 QFVTPVGTQNGLKATCAKISPDGQFLAITQGLNILIYDINRRTVSQTLVTSHARP----- 56 Query: 197 GITDWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSF 240 +S L WSP+G +A A +D V +I S+ Sbjct: 57 --------------FSELCWSPDGQCIATA-SDDFSVEIIHLSY 85 >6AGQ-A nrPDB Length = 321 Score = 34.0 bits (76), Expect = 0.24, Method: Composition-based stats. Identities = 58/307 (18%), Positives = 92/307 (29%), Gaps = 49/307 (15%) Query: 486 VNDKGLRVLEDNSALDKMLQNVQMPSKKLDFII---LNETKFWYQMILPPHFDKSKKYPL 542 N K L + A ++Q+ + S + ++ + T + P + P+ Sbjct: 29 DNAKALSNQKPLHAQVNLVQDYPLKSISIYDVVYDGADGTPIHGWYVTPKGEHQPGSLPV 88 Query: 543 LLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGY----QGDKIMHAI--NR 596 L+ + ++ L WA+ + + D RG G + + I Sbjct: 89 LVKYHGYSGNRGYPNEL-LQWASM-----GMAALAIDVRGQGGVTPDRAEYPQGGIPGWM 142 Query: 597 RLGTFE---------VEDQIEAARQFSKMGFVDNKRIAIWGWSYGGYVTSMVLGSGSGVF 647 LG + D I A VD RIA++G S GG + G S Sbjct: 143 TLGILDPASYYYKQVYLDCIRALDFVCSREEVDASRIAVYGGSQGGGLALAAAGLDSRP- 201 Query: 648 KCGIAVAPVSRWEYYDSV-------YTE--RYMGLPTPEDNLDH--YRNSTV---MSRAE 693 K + V P + SV Y E + PE + YR + M+ A Sbjct: 202 KLALPVFPF-LCHFRRSVEIHASGPYVEIKNWFRRYDPEHRQEEQVYRTLSYFDGMNMAS 260 Query: 694 NFKQVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYT 753 K + I D L + Y D H H Sbjct: 261 RIKARTLMAI-TLQDITCPPSTCFAAYNHLAG---PKEVRLYHDYGH----EGLPFH-EE 311 Query: 754 HMSHFIK 760 M FI+ Sbjct: 312 AMMRFIE 318 >4QWW-A nrPDB Length = 542 Score = 33.6 bits (75), Expect = 0.33, Method: Composition-based stats. Identities = 28/133 (21%), Positives = 49/133 (36%), Gaps = 9/133 (6%) Query: 535 DKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAI 594 + K P+L+ +Y G + +L T+N+I+ S R + + + Sbjct: 104 PRPKDAPVLVWIYGG-GFYSGAASLDVYDGRFLTYTQNVILVSLSYRVGAFGFLGLPGSP 162 Query: 595 NRRLGTFEVEDQIEAARQFSK--MGFVDNKR-IAIWGWSYGGYVTSMVLGSGSG--VFKC 649 G + DQ A + F N R + ++G S G M L S +F+ Sbjct: 163 EAP-GNMGLLDQRLALQWIQNNIHPFGGNPRAVTVFGESAGAASVGMHLLSTQSRTLFQR 221 Query: 650 GI--AVAPVSRWE 660 I + P + W Sbjct: 222 AILQSGGPNAPWA 234 >5HQ3-A nrPDB Length = 548 Score = 33.6 bits (75), Expect = 0.36, Method: Composition-based stats. Identities = 28/143 (19%), Positives = 53/143 (37%), Gaps = 9/143 (6%) Query: 526 YQMILPPHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYLASTENIIVASFDGRGSGY 585 Y + P+ P+++ +Y G + + +L TE +++ S + R + Sbjct: 99 YLNVWTPYPRPKNPAPVMVWIYGG-GFYSGSSSLDVYDGRFLVRTERVVLVSMNYRVGAF 157 Query: 586 QGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFV---DNKRIAIWGWSYGGYVTSMVLGS 642 + + G + DQ A + + D + ++G S G M L S Sbjct: 158 GFLALPGSREAP-GNVGLLDQRLALQWVQENIAAFGGDPTSVTLFGESAGAASVGMHLLS 216 Query: 643 GS--GVFKCGI--AVAPVSRWEY 661 G+F I + AP + W Y Sbjct: 217 PPSRGLFHRAILQSGAPNAPWAY 239 >3FOB-A nrPDB Length = 281 Score = 33.2 bits (74), Expect = 0.41, Method: Composition-based stats. Identities = 13/65 (20%), Positives = 27/65 (41%), Gaps = 4/65 (6%) Query: 697 QVEYLLIHGTADDNVHFQQSAQISKALVDVGVDFQAMWYTDEDHGIASSTAHQHIYTHMS 756 + L+IHG +D V F+ S +++ + HG+ ++ A + + Sbjct: 221 NIPTLIIHGDSDATVPFEYSGKLTHEAIPNSK---VALIKGGPHGLNATHAKE-FNEALL 276 Query: 757 HFIKQ 761 F+K Sbjct: 277 LFLKD 281 >5JOY-A nrPDB Length = 516 Score = 33.2 bits (74), Expect = 0.46, Method: Composition-based stats. Identities = 20/103 (19%), Positives = 32/103 (31%), Gaps = 8/103 (7%) Query: 335 GRWNCLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEEGYRHICYFQIDKKDC 394 G + E S W+ + + DG F ++SN +GY ++C Sbjct: 105 GNFLVHTTDPRSEWSEPVWLEQGGIDPSLYFEDGKCF--MVSNPDGYINLCEIDPMTGKQ 162 Query: 395 TFITKGTWE------VIGIEALTSDYLYYISNEYKGMPGGRNL 431 +K W G D YY+ G G + Sbjct: 163 LSSSKRIWNGTGGRYAEGPHIYKKDGWYYLLISEGGTELGHKV 205 >2E3J-A nrPDB Length = 356 Score = 32.9 bits (73), Expect = 0.51, Method: Composition-based stats. Identities = 11/67 (16%), Positives = 22/67 (32%), Gaps = 9/67 (13%) Query: 532 PHFDKSKKYPLLLDVYAGPCSQKADTVFRLNWATYL--ASTENIIVASFDGRGSGYQGDK 589 ++ PL++ ++ P S +W + + V + D RG G Sbjct: 19 ADSPPDQQGPLVVLLHGFPES-------WYSWRHQIPALAGAGYRVVAIDQRGYGRSSKY 71 Query: 590 IMHAINR 596 + R Sbjct: 72 RVQKAYR 78 >5W8P-A nrPDB Length = 370 Score = 32.9 bits (73), Expect = 0.52, Method: Composition-based stats. Identities = 15/87 (17%), Positives = 28/87 (32%), Gaps = 7/87 (8%) Query: 573 IIVASFDGRGSGYQGDKIMHAINRRLG----TFEVEDQIEA-ARQFSKMGFVDNKRIAIW 627 + + G G G + + G V DQ+ A +++G + A+ Sbjct: 91 AVATNVLGGCRGTTGPTSLARDGKPWGSRFPEVSVRDQVNADVAALAQLGITEVA--AVV 148 Query: 628 GWSYGGYVTSMVLGSGSGVFKCGIAVA 654 G S GG + + +A Sbjct: 149 GGSMGGARALEWAVMHPDAVRAALVLA 175 >5XMC-A nrPDB Length = 722 Score = 32.5 bits (72), Expect = 0.65, Method: Composition-based stats. Identities = 18/114 (15%), Positives = 37/114 (32%), Gaps = 5/114 (4%) Query: 271 VNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISLQWLRRIQNYSVMDICDY 330 +NT S + + ++ + DH TW E + W RR+ N + D+ Sbjct: 139 LNTVSQAPLPPGWEQRVDQHGRVYYVDHVEKRTTWDRPEPLPPGWERRVDNMGRIYYVDH 198 Query: 331 DESSGRWN-----CLVARQHIEMSTTGWVGRFRPSEPHFTLDGNSFYKIISNEE 379 + W + + ++ + G + F + N+E Sbjct: 199 FTRTTTWQRPTLESVRNYEQWQLQRSQLQGAMQQFNQRFIYGNQDLFATSQNKE 252 >4ZWN-A nrPDB Length = 334 Score = 32.5 bits (72), Expect = 0.69, Method: Composition-based stats. Identities = 12/83 (14%), Positives = 23/83 (27%), Gaps = 2/83 (2%) Query: 665 VYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQQSAQISKALV 724 +Y + Y+N + K +++HG D + S + + Sbjct: 229 LYGSFRQIHDFMQRGAKLYKNENNYIQKNFAKDKPVIIMHGQDDTINDPKGSEKFIRDCP 288 Query: 725 DVGVDFQAMWYTDEDHGIASSTA 747 + Y H I S Sbjct: 289 SADK--ELKLYPGARHSIFSLET 309 >1PV1-A nrPDB Length = 299 Score = 31.7 bits (70), Expect = 1.4, Method: Composition-based stats. Identities = 34/214 (15%), Positives = 66/214 (30%), Gaps = 38/214 (17%) Query: 527 QMILPPHFDKSKKYPLLLDVYA---GPCSQKADTVFRLNWATYLASTENIIVASFDGRGS 583 + F ++K+ P + + P + ++ Y I+ RG Sbjct: 36 KHYYAQDFPRNKRIPTVFYLSGLTCTPDNASEKAFWQFQADKY---GFAIVFPDTSPRGD 92 Query: 584 ------------GYQGDKIMHAINRRLGT-FEVEDQI--EAARQF---------SKMGFV 619 G ++A +++ D I E + K+ F+ Sbjct: 93 EVANDPEGSWDFGQGAGFYLNATQEPYAQHYQMYDYIHKELPQTLDSHFNKNGDVKLDFL 152 Query: 620 DNKRIAIWGWSYGGYVTSMVLGSG--SGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPE 677 DN +AI G S GGY G +K A AP+ + + ++ E Sbjct: 153 DN--VAITGHSMGGYGAICGYLKGYSGKRYKSCSAFAPIV--NPSNVPWGQKAFKGYLGE 208 Query: 678 DNL--DHYRNSTVMSRAENFKQVEYLLIHGTADD 709 + + Y ++ + L+ G +D Sbjct: 209 EKAQWEAYDPCLLIKNIRHVGDDRILIHVGDSDP 242 >6FYY-p nrPDB Length = 763 Score = 31.3 bits (69), Expect = 1.4, Method: Composition-based stats. Identities = 34/165 (20%), Positives = 62/165 (37%), Gaps = 26/165 (15%) Query: 24 PVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAE- 82 P VLL T + T +S T T+ + + LK +L +S+ ++ + L FN E Sbjct: 399 PSVLLAYWTPE-TNNSACTATIAEVPRGR-VLKTVNLVQVSNVTLHWQNQAEFLCFNVER 456 Query: 83 -YGNSSVFLENSTF------------DEFGHSINDYSISPDG-QFILLEYNYVKQWRHSY 128 + N E S+ ++ P G +F+ + + V ++ Sbjct: 457 HTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAI 516 Query: 129 TASYDIY---------DLNKRQLITEERIPNNTQWVTWSPVGHKL 164 A+ + D+ KR + +E V+WSP G + Sbjct: 517 PANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFV 561 >5K1H-B nrPDB Length = 576 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 34/144 (23%), Positives = 58/144 (40%), Gaps = 12/144 (8%) Query: 92 NSTFDEFGHSINDYSISPDGQ---FILLEYNYVKQWRHSYTASYDIYDLNKRQLITEERI 148 + F +FG ND+ DG+ +I LEY + D Y L+K+ Sbjct: 39 HKIFSKFGKITNDFYPEEDGKTKGYIFLEY-ASPAHAVDAVKNADGYKLDKQHTFRVNLF 97 Query: 149 PNNTQWVTWS-----PVGHKLAYVWNNDIYVKIEPNLPSYRITW-TGKEDIIY-NGITDW 201 + +++T S P + N +++ Y + + +G I+ N + D Sbjct: 98 TDFDKYMTISDEWDIPEKQPFKDLGNLRYWLEEAECRDQYSVIFESGDRTSIFWNDVKDP 157 Query: 202 V-YEEEVFSAYSALWWSPNGTFLA 224 V EE + + WSP GT+LA Sbjct: 158 VSIEERARWTETYVRWSPKGTYLA 181 >5A0Y-C nrPDB Length = 249 Score = 31.3 bits (69), Expect = 1.7, Method: Composition-based stats. Identities = 21/138 (15%), Positives = 39/138 (28%), Gaps = 20/138 (14%) Query: 512 KKLDFIILNETKFWYQMILPPHFDKSKKYPL------------LLDVYAGPCSQKADTVF 559 +KL I + P S PL +++ G + Sbjct: 26 EKLREISDEDVVKILGHRAPGEEYPSVHPPLEEMDEPEDAIREMVEPIDGAKAGDRVRYI 85 Query: 560 RLNWATYLASTENII---VASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKM 616 + + Y A + + RG+ I R D + +++ + Sbjct: 86 QFTDSMYFAPAQPYVRSRAYLCRYRGADAGTLSGRQIIETR-----ERDLEKISKELLET 140 Query: 617 GFVDNKRIAIWGWSYGGY 634 F D R + G S G+ Sbjct: 141 EFFDPARSGVRGKSVHGH 158 >4U1F-A nrPDB Length = 497 Score = 30.9 bits (68), Expect = 1.9, Method: Composition-based stats. Identities = 35/165 (21%), Positives = 63/165 (38%), Gaps = 26/165 (15%) Query: 24 PVVLLNKGTDDATADSRKTYTLTDYLKNTYRLKLYSLRWISDHEYLYKQENNILVFNAEY 83 P VLL T + T +S T T+ + + LK +L +S+ ++ + L FN E Sbjct: 231 PSVLLAYWTPE-TNNSACTATIAEVPRGR-VLKTVNLVQVSNVTLHWQNQAEFLCFNVER 288 Query: 84 GNSSVFLENSTFD--------------EFGHSINDYSISPDG-QFILLEYNYVKQWRHSY 128 S + S E S+ ++ P G +F+ + + V ++ Sbjct: 289 HTKSGKTQFSNLQICRLTERDIPVEKVELKDSVFEFGWEPHGNRFVTISVHEVADMNYAI 348 Query: 129 TASYDIY---------DLNKRQLITEERIPNNTQWVTWSPVGHKL 164 A+ + D+ KR + +E V+WSP G + Sbjct: 349 PANTIRFYAPETKEKTDVIKRWSLVKEIPKTFANTVSWSPAGRFV 393 >2PCM-A nrPDB Length = 265 Score = 30.5 bits (67), Expect = 2.6, Method: Composition-based stats. Identities = 20/114 (17%), Positives = 42/114 (36%) Query: 200 DWVYEEEVFSAYSALWWSPNGTFLAYAQFNDTEVPLIEYSFYSDESLQYPKTVRVPYPKA 259 D + E ++ L+ Y N+ L++ + T+ V +A Sbjct: 150 DVIKENAERGLHTLLFLDIKAEKRMYMTANEAMELLLKVEDMKKGGVFTDDTLVVVLARA 209 Query: 260 GAVNPTVKFFVVNTDSLSSVTNATSIQITAPASMLIGDHYLCDVTWATQERISL 313 G++NPT++ V + I I ++ YL ++ A +E + + Sbjct: 210 GSLNPTIRAGYVKDLIREDFGDPPHILIVPGKLHIVEAEYLVEIAGAPREILRV 263 >3AV7-A nrPDB Length = 448 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 64/190 (33%), Gaps = 15/190 (7%) Query: 488 DKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVY 547 + G V+ + LQ + I L++ +++ + + + VY Sbjct: 162 NPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVY 221 Query: 548 AGPCSQK----ADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEV 603 P Q R + LAS + IV D Y + +++ + Sbjct: 222 TVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDD----PYGELRYSGNPEKKIKALDN 277 Query: 604 EDQIEAARQFSKMGFVDNKRIAIWGWSYG--GYVTSMVLGSGSGVFKCGIAVAPVSRWEY 661 E ++ FSK+ RI GW G G + M + S C V W Y Sbjct: 278 EGRVIYLGTFSKI-LAPGFRI---GWMVGDPGIIRKMEIAKQSTDL-CTNVFGQVVAWRY 332 Query: 662 YDSVYTERYM 671 D Y E+++ Sbjct: 333 VDGGYLEKHI 342 >1X0M-A nrPDB Length = 403 Score = 30.5 bits (67), Expect = 2.7, Method: Composition-based stats. Identities = 37/190 (19%), Positives = 64/190 (33%), Gaps = 15/190 (7%) Query: 488 DKGLRVLEDNSALDKMLQNVQMPSKKLDFIILNETKFWYQMILPPHFDKSKKYPLLLDVY 547 + G V+ + LQ + I L++ +++ + + + VY Sbjct: 117 NPGDIVVVEAPTYLAALQAFNFYEPQYIQIPLDDEGMKVEILEEKLKELKSQGKKVKVVY 176 Query: 548 AGPCSQK----ADTVFRLNWATYLASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEV 603 P Q R + LAS + IV D Y + +++ + Sbjct: 177 TVPTFQNPAGVTMNEDRRKYLLELASEYDFIVVEDD----PYGELRYSGNPEKKIKALDN 232 Query: 604 EDQIEAARQFSKMGFVDNKRIAIWGWSYG--GYVTSMVLGSGSGVFKCGIAVAPVSRWEY 661 E ++ FSK+ RI GW G G + M + S C V W Y Sbjct: 233 EGRVIYLGTFSKI-LAPGFRI---GWMVGDPGIIRKMEIAKQSTDL-CTNVFGQVVAWRY 287 Query: 662 YDSVYTERYM 671 D Y E+++ Sbjct: 288 VDGGYLEKHI 297 >3NC3-A nrPDB Length = 441 Score = 30.2 bits (66), Expect = 3.2, Method: Composition-based stats. Identities = 14/54 (25%), Positives = 23/54 (42%), Gaps = 1/54 (1%) Query: 655 PVSRWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLL-IHGTA 707 PV E DS + RY + + D + +++ RAE + L +HG Sbjct: 67 PVHYEESIDSYFISRYHDVRYILQHPDIFTTKSLVERAEPVMRGPVLAQMHGKE 120 >4G5X-A nrPDB Length = 279 Score = 30.2 bits (66), Expect = 3.7, Method: Composition-based stats. Identities = 25/143 (17%), Positives = 46/143 (32%), Gaps = 17/143 (11%) Query: 568 ASTENIIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDN-----K 622 +S+ I +G G K G + D I+ R +S G+ D + Sbjct: 34 SSSGAIFAPQLEGE----IGKKWRVIAPDLPGHGKSTDAIDPDRSYSMEGYADAMTEVMQ 89 Query: 623 RIAI-----WGWSYGGYVTSMVLGSGSGVFKCGIAVAPVSRWEYYDSVYTERYMGLPTPE 677 ++ I +GWS GG++ ++ + I P E + G Sbjct: 90 QLGIADAVVFGWSLGGHIGIEMIARYPEMRGLMITGTPPVAREEVGQGFKS---GPDMAL 146 Query: 678 DNLDHYRNSTVMSRAENFKQVEY 700 + + V S A + + Sbjct: 147 AGQEIFSERDVESYARSTCGEPF 169 >3IB3-A nrPDB Length = 560 Score = 29.8 bits (65), Expect = 4.7, Method: Composition-based stats. Identities = 22/144 (15%), Positives = 38/144 (26%), Gaps = 22/144 (15%) Query: 573 IIVASFDGRGSGYQGDKIMHAINRRLGTFEVEDQIEAARQFSKMGFVDNKRIAIWGWSYG 632 +V RGS DK ++ E ED E + + + I G SY Sbjct: 118 YVVVKVALRGS----DKSKGVLS-PWSKREAEDYYEVIEWAANQSWSNGN-IGTNGVSYL 171 Query: 633 GYVTSMVLGSGS-------------GVFKCGIAVAPVSRWEYY---DSVYTERYMGLPTP 676 V +++ + +Y R+ P Sbjct: 172 AVTQWWVASLNPPHLKAMIPWEGLNDMYREVAFHGGIPDTGFYRFWTQGIFARWTDNPNI 231 Query: 677 EDNLDHYRNSTVMSRAENFKQVEY 700 ED + + + +QV Sbjct: 232 EDLIQAQQEHPLFDDFWKQRQVPL 255 >5MP7-A nrPDB Length = 326 Score = 29.8 bits (65), Expect = 4.9, Method: Composition-based stats. Identities = 14/70 (20%), Positives = 24/70 (34%), Gaps = 5/70 (7%) Query: 658 RWEYYDSVYTERYMGLPTPEDNLDHYRNSTVMSRAENFKQVEYLLIHGTADDNVHFQ-QS 716 Y Y + M + +P+ R A++ V IH T D V Q +S Sbjct: 159 LTGYIGEHYADEDMVVVSPDSG----RVRVAEKWADSLGGVPLAFIHKTRDPLVPNQVKS 214 Query: 717 AQISKALVDV 726 ++ + Sbjct: 215 NRVVGDVKGK 224 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.307 0.122 0.319 Lambda K H 0.267 0.0377 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,725,443 Number of Sequences: 36641 Number of extensions: 1088046 Number of successful extensions: 3342 Number of sequences better than 10.0: 131 Number of HSP's better than 10.0 without gapping: 83 Number of HSP's successfully gapped in prelim test: 83 Number of HSP's that attempted gapping in prelim test: 2976 Number of HSP's gapped (non-prelim): 203 length of query: 766 length of database: 10,336,785 effective HSP length: 105 effective length of query: 661 effective length of database: 6,489,480 effective search space: 4289546280 effective search space used: 4289546280 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.2 bits) S2: 63 (29.0 bits)