BLASTP 2.2.23 [Feb-03-2010] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Reference for compositional score matrix adjustment: Altschul, Stephen F., John C. Wootton, E. Michael Gertz, Richa Agarwala, Aleksandr Morgulis, Alejandro A. Schaffer, and Yi-Kuo Yu (2005) "Protein database searches using compositionally adjusted substitution matrices", FEBS J. 272:5101-5109. Reference for composition-based statistics starting in round 2: Schaffer, Alejandro A., L. Aravind, Thomas L. Madden, Sergei Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST protein database searches with composition-based statistics and other refinements", Nucleic Acids Res. 29:2994-3005. Query= P27338 (520 letters) Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta 36,641 sequences; 10,336,785 total letters Searching..................................................done Results from round 1 Score E Sequences producing significant alignments: (bits) Value 2BK5-A nrPDB 1077 0.0 2BXR-A nrPDB 808 0.0 1O5W-A nrPDB 798 0.0 3RHA-A nrPDB 209 3e-54 6CR0-A nrPDB 107 1e-23 2VVL-G nrPDB 96 5e-20 3NK2-X nrPDB 92 5e-19 4FWE-A nrPDB 85 6e-17 1F8S-A nrPDB 80 2e-15 1REO-A nrPDB 70 2e-12 3KVE-A nrPDB 67 1e-11 3ABT-A nrPDB 62 8e-10 5L3D-A nrPDB 62 8e-10 3L1R-A nrPDB 59 6e-09 3BI4-A nrPDB 54 1e-07 4IV9-A nrPDB 47 2e-05 5MOG-A nrPDB 44 1e-04 1SEZ-A nrPDB 44 2e-04 2JB2-A nrPDB 43 3e-04 4IVM-B nrPDB 42 5e-04 4DGK-A nrPDB 41 0.001 4C5O-A nrPDB 40 0.002 3X0V-A nrPDB 40 0.003 3LOV-A nrPDB 40 0.003 5NMX-A nrPDB 39 0.005 2IVE-A nrPDB 39 0.005 3KYB-A nrPDB 39 0.005 3I6D-A nrPDB 39 0.007 3WE0-A nrPDB 38 0.008 3UP5-A nrPDB 38 0.012 4ZCC-A nrPDB 36 0.031 5ZBC-A nrPDB 36 0.037 4K22-A nrPDB 36 0.041 2CVJ-A nrPDB 36 0.049 4C3X-A nrPDB 36 0.050 1I8T-A nrPDB 35 0.070 2TMD-A nrPDB 35 0.077 3MJ4-A nrPDB 35 0.086 3KKJ-A nrPDB 35 0.099 4AP1-A nrPDB 35 0.12 4N9X-A nrPDB 34 0.12 2VOU-A nrPDB 34 0.19 3ATQ-A nrPDB 33 0.20 2BS2-A nrPDB 33 0.28 1DOD-A nrPDB 33 0.31 3BHF-A nrPDB 33 0.33 4MO2-B nrPDB 33 0.34 4Y4N-A nrPDB 33 0.35 3K30-A nrPDB 33 0.38 3NIX-A nrPDB 33 0.40 4OVI-A nrPDB 33 0.44 3LXD-A nrPDB 33 0.44 4Y4M-A nrPDB 32 0.55 4QLO-A nrPDB 32 0.64 2RGJ-A nrPDB 32 0.68 5X68-A nrPDB 32 0.71 4A6N-B nrPDB 32 0.77 1V59-A nrPDB 32 0.82 3IHG-A nrPDB 32 0.85 4HA6-A nrPDB 31 1.1 3L9K-A nrPDB 31 1.1 4YNU-A nrPDB 31 1.3 4RPJ-A nrPDB 31 1.3 5BR7-A nrPDB 31 1.4 4RG3-A nrPDB 31 1.5 6ER9-A nrPDB 31 1.6 6DLL-A nrPDB 31 1.6 5TUK-A nrPDB 30 2.0 2GMH-A nrPDB 30 2.0 1ZOV-A nrPDB 30 2.0 2YQU-A nrPDB 30 2.8 4P9S-A nrPDB 30 3.6 2UYG-A nrPDB 29 4.0 3RP7-A nrPDB 29 4.2 5L46-A nrPDB 29 4.3 5BSW-A nrPDB 29 4.3 1GPJ-A nrPDB 29 4.5 2EEZ-A nrPDB 29 4.7 3NTA-A nrPDB 29 4.7 4XDY-A nrPDB 29 4.9 5EQD-A nrPDB 29 5.1 6BRD-A nrPDB 29 5.1 3UKH-A nrPDB 29 5.2 3FG2-P nrPDB 29 5.6 4JDR-A nrPDB 29 5.9 2VHY-A nrPDB 28 7.9 5OC1-A nrPDB 28 7.9 5EZ7-A nrPDB 28 8.3 1ULZ-A nrPDB 28 8.7 6J0Z-C nrPDB 28 9.2 6C6P-A nrPDB 28 9.5 4USR-A nrPDB 28 9.7 4J0E-A nrPDB 28 9.7 >2BK5-A nrPDB Length = 520 Score = 1077 bits (2786), Expect = 0.0, Method: Compositional matrix adjust. Identities = 519/520 (99%), Positives = 519/520 (99%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY Sbjct: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR Sbjct: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 Query: 121 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV 180 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV Sbjct: 121 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV 180 Query: 181 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ 240 SALWFLWYVKQCGGTTRI STTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ Sbjct: 181 SALWFLWYVKQCGGTTRIFSTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ 240 Query: 241 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY 300 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY Sbjct: 241 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY 300 Query: 301 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER 360 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER Sbjct: 301 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER 360 Query: 361 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR 420 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR Sbjct: 361 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR 420 Query: 421 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT 480 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT Sbjct: 421 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT 480 Query: 481 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV 520 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV Sbjct: 481 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV 520 >2BXR-A nrPDB Length = 527 Score = 808 bits (2086), Expect = 0.0, Method: Compositional matrix adjust. Identities = 376/514 (73%), Positives = 447/514 (86%), Gaps = 2/514 (0%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DVVV+GGGISG++AAKLL + G++V+VLEARDRVGGRTYT+RN+ V YVD+GG+YVGPTQ Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQ 74 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 NRILRL+KELG+ETYKVN ERL+ +VKGK+YPFRG FPPVWNPI YLD+NN WRT+D+M Sbjct: 75 NRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNM 134 Query: 126 GREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWF 185 G+EIP+DAPW+A A++WD MTMKEL+DK+CWT++A++ A LFVN+ VT+E HEVSALWF Sbjct: 135 GKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWF 194 Query: 186 LWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENV 245 LWYVKQCGGTTRI S TNGGQERKFVGGSGQVSERIMDLLGD+VKL PV ++DQ+ +N+ Sbjct: 195 LWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNI 254 Query: 246 LVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305 ++ETLNHE YE KYVI+AIPPTL KIHF P LP RNQ+I R+P+G+VIKC++YYKE F Sbjct: 255 IIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAF 314 Query: 306 WRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLC 365 W+KKDYCG MII+ E+AP++ TLDDTKP+G+ AIMGFILA KA +LA+L KE R KK+C Sbjct: 315 WKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKIC 374 Query: 366 ELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAG 425 ELYAKVLGS EAL PVHYEEKNWCEEQYSGGCYT YFPPGI+TQYGRV+RQPV RI+FAG Sbjct: 375 ELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAG 434 Query: 426 TETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERH 485 TETAT WSGYMEGAVEAGERAARE+L+ +GK+ E +IW EPES DVPA IT TF ER+ Sbjct: 435 TETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERN 494 Query: 486 LPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVR 519 LPSV GLL++IG +T S TALGF+ +K LL R Sbjct: 495 LPSVSGLLKIIGFST--SVTALGFVLYKYKLLPR 526 >1O5W-A nrPDB Length = 534 Score = 798 bits (2061), Expect = 0.0, Method: Compositional matrix adjust. Identities = 374/508 (73%), Positives = 440/508 (86%), Gaps = 2/508 (0%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DVVV+GGGISG+AAAKLL + +NV+VLEARDRVGGRTYT+RN+ VK+VD+GG+YVGPTQ Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQ 82 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 NRILRL+KELG+ETYKVN ERL+ +VKGK+YPFRG FPPVWNP+ YLD+NN WRTMD+M Sbjct: 83 NRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEM 142 Query: 126 GREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWF 185 G+EIP DAPW+A A+EWD MTMK+L+DK+CWT++A++ A LFVN+ VT+E HEVSALWF Sbjct: 143 GKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWF 202 Query: 186 LWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENV 245 LWYV+QCGGT RI S TNGGQERKFVGGSGQVSE+IM LLGD+VKL PV YIDQT +N+ Sbjct: 203 LWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNI 262 Query: 246 LVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305 +VETLNHE YE KYVISAIPP L KIHF P LP RNQ+I R+P+G+VIKC+VYYKE F Sbjct: 263 IVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAF 322 Query: 306 WRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLC 365 W+KKDYCG MII+ EEAP+A TLDDTKP+G+ AIMGFILA KA +LA+L K+ R +K+C Sbjct: 323 WKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRLAKLHKDIRKRKIC 382 Query: 366 ELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAG 425 ELYAKVLGS EAL PVHYEEKNWCEEQYSGGCYT YFPPGI+TQYGRV+RQPV RIYFAG Sbjct: 383 ELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAG 442 Query: 426 TETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERH 485 TETAT WSGYMEGAVEAGERAARE+L+A+GK+ + +IW EPES DVPA IT TFLER+ Sbjct: 443 TETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERN 502 Query: 486 LPSVPGLLRLIGLTTIFSATALGFLAHK 513 LPSVPGLL++ G++T S L F+ +K Sbjct: 503 LPSVPGLLKITGVST--SVALLCFVLYK 528 >3RHA-A nrPDB Length = 482 Score = 209 bits (531), Expect = 3e-54, Method: Compositional matrix adjust. Identities = 148/450 (32%), Positives = 223/450 (49%), Gaps = 9/450 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DVV+VG G SG+ AA+ L +GL+V VLEARDRVGGRT+T +++GG +V P Q Sbjct: 9 DVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGRTWT-DTIDGAMLEIGGQWVSPDQ 67 Query: 66 NRILRLAKELGLETY-KVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDD 124 ++ L ELGL+ Y + + E + GK + G PV N T + + +D+ Sbjct: 68 TVLMELLDELGLKMYSRYRDGESVYIGADGKRTQYTGDTFPV-NETTKAEMDKLVAILDE 126 Query: 125 MGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFV-NLCVTAETHEVSAL 183 + EI PW P A E D ++ L + E A LF+ +T H SAL Sbjct: 127 LAAEIGPTEPWAHPKARELDTISFHHWLRQNSNDEEACNNIGLFIAGGMLTKPAHAFSAL 186 Query: 184 WFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRE 243 + G + + + + +++ +GG QVS LGD V L PV I + E Sbjct: 187 QAVLMAASAGSFSHL-TDEDFILDKRVIGGMQQVSLLQAAELGDDVVLNSPVRTI-KWDE 244 Query: 244 NVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKE 303 N + A++VI A+PP L ++ F+PPLP ++QM LG VIK Y Sbjct: 245 NGVSVVSERATVNARFVIMAVPPNLYSRVSFDPPLPRRQHQMHQHQSLGLVIKVHAVYDT 304 Query: 304 PFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKK 363 PFWR++ GT G A V D+T + ++GF+ KA + L+ E+R K Sbjct: 305 PFWREEGLSGTGFSAG--ALVQEVYDNTNHGDSRGTLVGFVSDEKADAVFELSAEDRKKA 362 Query: 364 LCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYF 423 + E A LG +AL P Y E +W E+++ G Y + + G L +YG+ V IY+ Sbjct: 363 ILESIAGFLGD-KALTPEVYYESDWGSEEWTRGAYASSYDLGGLHRYGKDQHANVGPIYW 421 Query: 424 AGTETATHWSGYMEGAVEAGERAAREILHA 453 + ++ A +++GAV G+ A I+ A Sbjct: 422 SSSDLAAEGYQHVDGAVRMGQATAARIVEA 451 >6CR0-A nrPDB Length = 440 Score = 107 bits (267), Expect = 1e-23, Method: Compositional matrix adjust. Identities = 110/455 (24%), Positives = 192/455 (42%), Gaps = 34/455 (7%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D +VVG G SG+ AA+ L G +V+++EAR R+GGRT+ + N + V++GG+ V Q Sbjct: 10 DAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVV-NFLGRPVEIGGAGVHWCQ 68 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLD--HNNFWRTMD 123 + + G +K + L K+Y + P D + + Sbjct: 69 PHVFAEMQRYGF-GFKEAPLADL-----DKAYMVFADGQKIDVPPATFDEEYTTAFEKFC 122 Query: 124 DMGREIPSD--APWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCV--TAETHE 179 RE+ +P D ++ ++ L+ L E QLA++ L + A T E Sbjct: 123 SRSRELFPRPYSPLDNHEVSNLDGVSARDHLESLGLNE--LQLASMNAELTLYGGAPTTE 180 Query: 180 VSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYID 239 +S F+ + T I+ T+ + GG+ + + I D + PV + Sbjct: 181 LSYPSFVKFHALASWDT--ITFTDSEKRYHVQGGTNALCQAIFDDCRADSEFGVPVEAVA 238 Query: 240 QTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIV 299 QT V V + ++ A + +P + + F PPLP + I + + V Sbjct: 239 QTDNGVTVTLADKRVFRALTCVLTLPTKVYADVRFEPPLPPEKRAFIEHAEMADGAELYV 298 Query: 300 YYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEE 359 + ++ +C + A Y DD I+ + ++ L E Sbjct: 299 HVRQNLGNTFTFCDDP--NPFNAVQTYAYDD-----ELGTILKITIGRQS-----LINLE 346 Query: 360 RLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVD 419 + K+ G +E LE + Y NW ++Y+ Y G ++Y + + +P + Sbjct: 347 NFDAIAAEIRKIHGDVEVLEALPY---NWAMDEYARTSYPA-MRKGWFSRY-KDMAKPEN 401 Query: 420 RIYFAGTETATHWSGYMEGAVEAGERAAREILHAM 454 R++FAG+ TA W Y++GA+E+G R REI H M Sbjct: 402 RLFFAGSATADGWHEYIDGAIESGIRVGREIRHFM 436 >2VVL-G nrPDB Length = 495 Score = 95.5 bits (236), Expect = 5e-20, Method: Compositional matrix adjust. Identities = 120/481 (24%), Positives = 202/481 (41%), Gaps = 58/481 (12%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DV+V+GGG G+ A + L +G ++LEARDR+GGR+++ Y ++GG++V Q Sbjct: 41 DVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSNIDGYPY-EMGGTWVHWHQ 99 Query: 66 NRILRLAKELGLETYKVNEVERL-IHHVKGKSYPF-RG--PFPPVWNPI--TYLDH---- 115 + + R E+ R +H+ S+ F RG F NP TY+ H Sbjct: 100 SHVWR-------------EITRYKMHNALSPSFNFSRGVNHFQLRTNPTTSTYMTHEAED 146 Query: 116 -------NNFWRTMDDMGREI---PSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLA 165 + F GR + P D + P ++D M+ E +D++ S + + Sbjct: 147 ELLRSALHKFTNVDGTNGRTVLPFPHDM-FYVPEFRKYDEMSYSERIDQIRDELSLNERS 205 Query: 166 TL--FVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMD 223 +L F+ LC S FL + G T + + KF G + R + Sbjct: 206 SLEAFILLCSGGTLENSSFGEFLHWWAMSGYTYQ--GCMDCLMSYKFKDGQSAFARRFWE 263 Query: 224 LLGDRVKLER----PVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLP 279 +L PV + R+ V + + AK V+ IP + I F+P L Sbjct: 264 EAAGTGRLGYVFGCPVRSVVNERDAARVTARDGREFVAKRVVCTIPLNVLSTIQFSPALS 323 Query: 280 MMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTL-DDTKPEGNYA 338 R I+ + G V C + E KD I + Y + D T P GN Sbjct: 324 TER---ISAMQAGHVSMCTKVHAEV--DNKDMRSWTGIAYPFNKLCYAIGDGTTPAGNTH 378 Query: 339 AIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCY 398 + A+ + + E LK + +L G + H NW +++++ G + Sbjct: 379 LVCFGTDANHIQPDEDV--RETLKAVGQLAPGTFGVKRLV--FH----NWVKDEFAKGAW 430 Query: 399 TTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIP 458 + PG++++ + LR+ + FA ++ A W +++GA+E G RAAR +L +G Sbjct: 431 -FFSRPGMVSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVLEELGTKR 489 Query: 459 E 459 E Sbjct: 490 E 490 >3NK2-X nrPDB Length = 431 Score = 92.0 bits (227), Expect = 5e-19, Method: Compositional matrix adjust. Identities = 113/461 (24%), Positives = 190/461 (41%), Gaps = 55/461 (11%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK--YVDLGGSYVGP 63 D +VVGGG SG+ AA+ L ++G V++LE +R+GGR Y+ ++ V V++GG+Y+ Sbjct: 3 DAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLHR 62 Query: 64 TQNRILRLAKEL---GLETYKVNEVERLIHHVK----GKSYPFRGPFPPVWNPITYLDHN 116 + RLA EL G+ T +E H + +++P G TY Sbjct: 63 KHHP--RLAAELDRYGIPTAAASEFTSFRHRLGPTAVDQAFPIPGSEAVAVEAATYTLLR 120 Query: 117 NFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAE 176 + R + G E PL E +DKL ++Q + + Sbjct: 121 DAHRIDLEKGLENQDLEDLDIPL---------NEYVDKLDLPPVSRQFLLAWAWNMLGQP 171 Query: 177 THEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVI 236 + SALW L V + + + + F GS + + + + + ++L+ V Sbjct: 172 ADQASALWMLQLVAAHHYSILGVVLS---LDEVFSNGSADLVDAMSQEIPE-IRLQTVVT 227 Query: 237 YIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIK 296 IDQ+ + V V + ++A VI A P +I F P LP R +I G +K Sbjct: 228 GIDQSGDVVNVTVKDGHAFQAHSVIVATPMNTWRRIVFTPALPERRRSVIEEGHGGQGLK 287 Query: 297 CIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPE-GNYAAIMGFILAHKARKLARL 355 +++ + G EA + D P +Y + + R L Sbjct: 288 ILIHVR----------------GAEAGIECVGDGIFPTLYDYCEV-----SESERLLVAF 326 Query: 356 TKEERLK--KLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRV 413 T + + VL L +E + + +W + G + P + Q+ RV Sbjct: 327 TDSGSFDPTDIGAVKDAVLYYLPEVEVLGIDYHDWIADPLFEGPWVA---PRV-GQFSRV 382 Query: 414 ---LRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREIL 451 L +P RI+F G++ + + GY+EGA+E E A IL Sbjct: 383 HKELGEPAGRIHFVGSDVSLEFPGYIEGALETAECAVNAIL 423 >4FWE-A nrPDB Length = 796 Score = 85.1 bits (209), Expect = 6e-17, Method: Compositional matrix adjust. Identities = 108/462 (23%), Positives = 193/462 (41%), Gaps = 45/462 (9%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV-GPTQ 65 V+++G G +G+AAA+ LH+ G+ V VLEA+DR+GGR + ++ K V G V G Sbjct: 359 VIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGCIN 418 Query: 66 NRILRLAKELGLETYKVNEVERLIHH---VKGKSYPFRGPFPPVWNPITYLDHNNFWRTM 122 N + + ++LG+ +K E LI + + R F +N + LD + WR Sbjct: 419 NPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH--FNAL--LDVVSEWRKD 474 Query: 123 DDMGREIP----SDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETH 178 +++P + +KA + E + EL ++ Q + + H Sbjct: 475 KTQLQDVPLGEKIEEIYKAFIKES--GIQFSELEGQVL------QFHLSNLEYACGSNLH 526 Query: 179 EVSALWFLW----YVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERP 234 +VSA W + Q G +++ G + E++ + G ++L+ P Sbjct: 527 QVSAR--SWDHNEFFAQFAGDHTLLTP-----------GYSVIIEKLAE--GLDIQLKSP 571 Query: 235 VIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMK--IHFNPPLPMMRNQMITRVPLG 292 V ID + + V V T + Y A+ V+ +P L K I FNPPL + + I + G Sbjct: 572 VQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAG 631 Query: 293 SVIKCIVYYKEPFWRKK----DYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHK 348 + K + + FW K D+ G + + + D P+ ++ +M I Sbjct: 632 IIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEA 691 Query: 349 ARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILT 408 + L ++ L++ ++ E +P Y W + + Y+ G Sbjct: 692 VASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGE 751 Query: 409 QYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREI 450 Y + ++FAG T H+ + GA +G R A +I Sbjct: 752 AYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 793 >1F8S-A nrPDB Length = 498 Score = 80.5 bits (197), Expect = 2e-15, Method: Compositional matrix adjust. Identities = 113/476 (23%), Positives = 187/476 (39%), Gaps = 53/476 (11%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSY 60 SN VV+VG G++G++AA +L +G V VLEA +R GGR T RN++ Y +LG Sbjct: 31 SNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANLGPMR 90 Query: 61 VGPTQNRILR------------LAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPP--V 106 + P ++RI+R ++E Y + + + + VK + P P Sbjct: 91 L-PEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKYPVKPSEA 149 Query: 107 WNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLAT 166 L + + ++++ R S + ++D + KE L K + + Sbjct: 150 GKSAGQLYEESLGKVVEELKRTNCS------YILNKYDTYSTKEYLIK--EGDLSPGAVD 201 Query: 167 LFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLG 226 + +L + VS + L + R + V G ++ + + Sbjct: 202 MIGDLLNEDSGYYVSFIESLKHDDIFAYEKRF---------DEIVDGMDKLPTAMYRDIQ 252 Query: 227 DRVKLERPVIYIDQTRENVLV--ETLNHEM--YEAKYVISAIPPTLGMKIHFNPPLPMMR 282 D+V VI I Q + V V ETL+ E A YVI I FNPPL + Sbjct: 253 DKVHFNAQVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCTTSRAVRLIKFNPPLLPKK 312 Query: 283 NQMITRVPLGSVIKCIVYYKEPFWRKKD-YCGTMIIDGEEAPVAYTLDDTKPEGNYAAIM 341 + V S K + FW + G D + Y P N+ + Sbjct: 313 AHALRSVHYRSGTKIFLTCTTKFWEDDGIHGGKSTTDLPSRFIYY------PNHNFTNGV 366 Query: 342 GFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEE-------KNWCEEQYS 394 G I+A+ A + K ++ L + L + + W ++Y+ Sbjct: 367 GVIIAYGIGDDANFFQALDFKDCADIVFNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYA 426 Query: 395 GGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREI 450 G TT F P + L RIYFAG TA G+++ +++G RAAR++ Sbjct: 427 MGGITT-FTPYQFQHFSDPLTASQGRIYFAGEYTA-QAHGWIDSTIKSGLRAARDV 480 >1REO-A nrPDB Length = 486 Score = 70.1 bits (170), Expect = 2e-12, Method: Compositional matrix adjust. Identities = 70/265 (26%), Positives = 112/265 (42%), Gaps = 29/265 (10%) Query: 207 ERKF---VGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLV--ETLNHEMYE--AKY 259 E++F VGG ++ + + ++V L VI I + E V V +T EM A Y Sbjct: 230 EKRFDEIVGGMDKLPTSMYRAIEEKVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTADY 289 Query: 260 VISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKD-YCGTMIID 318 VI +I F PPLP + + V S K + + FW + + G D Sbjct: 290 VIVCTTSRATRRIKFEPPLPPKKAHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGKSTTD 349 Query: 319 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEAL 378 + Y P N+ + +G I+A+ A + K ++ V+ L + Sbjct: 350 LPSRFIYY------PNHNFTSGVGVIIAYGIGDDANFFQALDFKDCADI---VINDLSLI 400 Query: 379 EPVHYEE----------KNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTET 428 + EE + W ++Y+ G TT F P + L VDRIYFAG T Sbjct: 401 HQLPREEIQTFCYPSMIQKWSLDKYAMGGITT-FTPYQFQHFSESLTASVDRIYFAGEHT 459 Query: 429 ATHWSGYMEGAVEAGERAAREILHA 453 A G+++ +++G RAAR++ A Sbjct: 460 A-EAHGWIDSTIKSGLRAARDVNRA 483 Score = 57.8 bits (138), Expect = 1e-08, Method: Compositional matrix adjust. Identities = 36/79 (45%), Positives = 50/79 (63%), Gaps = 3/79 (3%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSY 60 SN VVVVG G+SG++AA +L +G V VLEA +R GGR T RN K Y +LG Sbjct: 31 SNPKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLGPMR 90 Query: 61 VGPTQNRILR-LAKELGLE 78 + P ++RI+R ++ GL+ Sbjct: 91 L-PEKHRIVREYIRKFGLQ 108 >3KVE-A nrPDB Length = 486 Score = 67.4 bits (163), Expect = 1e-11, Method: Compositional matrix adjust. Identities = 66/265 (24%), Positives = 105/265 (39%), Gaps = 29/265 (10%) Query: 207 ERKF---VGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHE----MYEAKY 259 E++F VGG Q+ + + ++VK VI I Q V V E A Y Sbjct: 230 EKRFDEIVGGMDQLPTSMYRAIEEKVKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADY 289 Query: 260 VISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKD-YCGTMIID 318 VI +I F PPLP + + V S K + FW + G D Sbjct: 290 VIVCTTSRAARRIQFEPPLPPKKQHALRSVHYRSGTKIFLTCSSKFWEDDGIHGGKSTTD 349 Query: 319 GEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEAL 378 + Y P N++ +G I+A+ A + + K ++ V L + Sbjct: 350 LPSRFIYY------PNHNFSTGVGVIIAYGIGDDANFFQALKFKDCADI---VFNDLSLI 400 Query: 379 EPVHYEE----------KNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTET 428 + EE + W ++Y+ G TT F P ++ L P RI+FAG T Sbjct: 401 HQLPKEEIQSFCYPSMIQKWSLDKYAMGAITT-FTPYQFQRFSEALTAPQGRIFFAGEYT 459 Query: 429 ATHWSGYMEGAVEAGERAAREILHA 453 A G+++ +++G AAR++ A Sbjct: 460 A-EAHGWIDSTIKSGLTAARDVNRA 483 Score = 56.2 bits (134), Expect = 3e-08, Method: Compositional matrix adjust. Identities = 34/70 (48%), Positives = 45/70 (64%), Gaps = 2/70 (2%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSY 60 SN VVVVG G+SG++AA +L +G V VLEA +R GGR T RN K Y +LG Sbjct: 31 SNPKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRNSKEGWYANLGPMR 90 Query: 61 VGPTQNRILR 70 + P ++RI+R Sbjct: 91 I-PEKHRIVR 99 >3ABT-A nrPDB Length = 662 Score = 61.6 bits (148), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 37/94 (39%), Positives = 59/94 (62%), Gaps = 5/94 (5%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSYV-GPT 64 V+++G G+SG+AAA+ L G++V +LEARDRVGGR T R K YV DLG V G Sbjct: 110 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLG 167 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYP 98 N + ++K++ +E K+ + + ++ G++ P Sbjct: 168 GNPMAVVSKQVNMELAKIKQ-KCPLYEANGQAVP 200 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 39/209 (18%), Positives = 79/209 (37%), Gaps = 30/209 (14%) Query: 260 VISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKK----DYCGTM 315 V+ PP + F PPLP + + R+ G++ K ++ + FW + G+ Sbjct: 458 VLKQQPPA----VQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGST 513 Query: 316 IIDGEEAPVAYTLDDTKPEGNYAA--IMGFILAHKARKLARLTKEERLKKLCELYAKVLG 373 E + + L Y A ++ + A + ++ + + + + + G Sbjct: 514 TASRGELFLFWNL--------YKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFG 565 Query: 374 SLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLR------------QPVDRI 421 S +P W + ++ G Y+ Y + + QP+ R+ Sbjct: 566 SSAVPQPKETVVSRWRADPWARGSYSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRL 625 Query: 422 YFAGTETATHWSGYMEGAVEAGERAAREI 450 +FAG T ++ + GA+ +G R A I Sbjct: 626 FFAGEHTIRNYPATVHGALLSGLREAGRI 654 >5L3D-A nrPDB Length = 852 Score = 61.6 bits (148), Expect = 8e-10, Method: Compositional matrix adjust. Identities = 37/94 (39%), Positives = 59/94 (62%), Gaps = 5/94 (5%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSYV-GPT 64 V+++G G+SG+AAA+ L G++V +LEARDRVGGR T R K YV DLG V G Sbjct: 281 VIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGLG 338 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYP 98 N + ++K++ +E K+ + + ++ G++ P Sbjct: 339 GNPMAVVSKQVNMELAKIKQ-KCPLYEANGQAVP 371 Score = 39.3 bits (90), Expect = 0.004, Method: Compositional matrix adjust. Identities = 49/239 (20%), Positives = 92/239 (38%), Gaps = 43/239 (17%) Query: 260 VISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKK----DYCGTM 315 V+ PP + F PPLP + + R+ G++ K ++ + FW + G+ Sbjct: 629 VLKQQPPA----VQFVPPLPEWKTSAVQRMGFGNLNKVVLCFDRVFWDPSVNLFGHVGST 684 Query: 316 IIDGEEAPVAYTLDDTKPEGNYAA--IMGFILAHKARKLARLTKEERLKKLCELYAKVLG 373 E + + L Y A ++ + A + ++ + + + + + G Sbjct: 685 TASRGELFLFWNL--------YKAPILLALVAGEAAGIMENISDDVIVGRCLAILKGIFG 736 Query: 374 SLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLR------------QPVDRI 421 S +P W + ++ G ++ Y + + QP+ R+ Sbjct: 737 SSAVPQPKETVVSRWRADPWARGSHSYVAAGSSGNDYDLMAQPITPGPSIPGAPQPIPRL 796 Query: 422 YFAGTETATHWSGYMEGAV-----EAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQ 475 +FAG T ++ + GA+ EAG R A + L AM +P Q+ P VPAQ Sbjct: 797 FFAGEHTIRNYPATVHGALLSGLREAG-RIADQFLGAMYTLPR----QATP---GVPAQ 847 >3L1R-A nrPDB Length = 478 Score = 58.5 bits (140), Expect = 6e-09, Method: Compositional matrix adjust. Identities = 48/236 (20%), Positives = 106/236 (44%), Gaps = 12/236 (5%) Query: 228 RVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMK----IHFNPPLPMMRN 283 R++L + V I + V V+T ++ +Y A YV+ + +LG+ I F P LP + Sbjct: 230 RLQLNKVVREIKYSPGGVTVKTEDNSVYSADYVM--VSASLGVLQSDLIQFKPKLPTWKV 287 Query: 284 QMITRVPLGSVIKCIVYYKEPFW---RKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAI 340 + I + + + + FW + +++ V + P+ N + Sbjct: 288 RAIYQFDMAVYTMIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDAN--VL 345 Query: 341 MGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTT 400 + + ++R++ + + E+ ++ ++ K+ + + W +++ G ++ Sbjct: 346 LVTVTDEESRRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSN 405 Query: 401 YFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGK 456 + P G+ LR PV R+YF G T+ H++GY+ GA +G +A +++ K Sbjct: 406 W-PVGVNRYEYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQK 460 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/56 (41%), Positives = 40/56 (71%), Gaps = 2/56 (3%) Query: 7 VVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 V+VVG G+SG++AAK L ++G+ ++++LEA D +GGR + + V+LG ++V Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWV 61 >3BI4-A nrPDB Length = 516 Score = 54.3 bits (129), Expect = 1e-07, Method: Compositional matrix adjust. Identities = 26/58 (44%), Positives = 40/58 (68%), Gaps = 1/58 (1%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 K V+++G GI+G+ AA LH +G+ + +VLEARDRVGGR T+ + + D+G S+ Sbjct: 8 KKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASW 65 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 23/65 (35%), Positives = 28/65 (43%), Gaps = 1/65 (1%) Query: 387 NWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVD-RIYFAGTETATHWSGYMEGAVEAGER 445 NW + YS G Y+ FP + D RI FAG T +G GA E+G R Sbjct: 439 NWTRDPYSRGAYSACFPGDDPVDMVVAMSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRR 498 Query: 446 AAREI 450 A I Sbjct: 499 EATRI 503 Score = 33.5 bits (75), Expect = 0.23, Method: Compositional matrix adjust. Identities = 23/83 (27%), Positives = 36/83 (43%), Gaps = 14/83 (16%) Query: 241 TRE---NVLVETLNHEMYEAKYVISAIPPT-----------LGMKIHFNPPLPMMRNQMI 286 TRE NV V + +Y A YVI +P + L +I F PPL + Sbjct: 227 TREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPLKPVIQDAF 286 Query: 287 TRVPLGSVIKCIVYYKEPFWRKK 309 ++ G++ K I ++E W + Sbjct: 287 DKIHFGALGKVIFEFEECCWSNE 309 >4IV9-A nrPDB Length = 557 Score = 46.6 bits (109), Expect = 2e-05, Method: Compositional matrix adjust. Identities = 30/98 (30%), Positives = 52/98 (53%), Gaps = 7/98 (7%) Query: 7 VVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYT--LRNQKVKYV-DLGGSYVG 62 V +VG GISG+ AA L +G+ +VV+ E+RDR+GGR ++ + +Y+ ++G Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRFP 100 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIH---HVKGKSY 97 P+ + K+ G+ T ++ H +GK Y Sbjct: 101 PSATGLFHYLKKFGISTSTTFPDPGVVDTELHYRGKRY 138 >5MOG-A nrPDB Length = 497 Score = 44.3 bits (103), Expect = 1e-04, Method: Compositional matrix adjust. Identities = 23/71 (32%), Positives = 39/71 (54%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 VV+ G G++G++ AK L D+G ++LEARD +GG+ +++ + + G Sbjct: 20 VVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETGLHIFFGAYP 79 Query: 67 RILRLAKELGL 77 I L ELG+ Sbjct: 80 NIQNLFGELGI 90 Score = 30.4 bits (67), Expect = 2.1, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 21/38 (55%) Query: 415 RQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILH 452 R P++ Y AG T + MEGAV +G+ A+ ++ Sbjct: 433 RSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQSVVE 470 >1SEZ-A nrPDB Length = 504 Score = 43.5 bits (101), Expect = 2e-04, Method: Compositional matrix adjust. Identities = 27/86 (31%), Positives = 47/86 (54%), Gaps = 4/86 (4%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 V V+G G+SG+AAA L GLNV V EA + GG+ ++ + + D G + + ++ Sbjct: 16 VAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIW-DEGANTMTESEG 74 Query: 67 RILRLAKELGL---ETYKVNEVERLI 89 + L LGL + + +++ +R I Sbjct: 75 DVTFLIDSLGLREKQQFPLSQNKRYI 100 >2JB2-A nrPDB Length = 489 Score = 43.1 bits (100), Expect = 3e-04, Method: Compositional matrix adjust. Identities = 22/41 (53%), Positives = 28/41 (68%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLR 47 VVV+GGG +G+ +A L +G V VLEAR R GGR +T R Sbjct: 14 VVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGRVWTAR 54 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 52/232 (22%), Positives = 91/232 (39%), Gaps = 26/232 (11%) Query: 211 VGGSGQVSERIMDLLG-DRVKLERPVIYIDQTRENVLVETL---NHEMYEAKYVISAIPP 266 VGG ++ D +G D + V + E V VE + + A Y I IPP Sbjct: 235 VGGMDRIYYAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTIPP 294 Query: 267 TLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKD--YCGTMIIDGEEAPV 324 L ++ N P ++ + S K + Y +W +D Y G D + + + Sbjct: 295 HLVGRLQNNLPGDVL--TALKAAKPSSSGKLGIEYSRRWWETEDRIYGGASNTDKDISQI 352 Query: 325 AYTLDDTKPEGNYAAIMGFILAH-----KARKLARLTKEERLKKLCELYAKVLGSLEALE 379 + D +Y + G ++A+ + LT +RL K +++ G + Sbjct: 353 MFPYD------HYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEGSEIHGEKYTRD 406 Query: 380 PVHYEEKNWCEEQYSGGCYTTYFPPGILT------QYGRVLRQPVDRIYFAG 425 +W +YS + + G +Y ++L +PVD+IYFAG Sbjct: 407 ISSSFSGSWRRTKYSESAWANWAGSGGSHGGAATPEYEKLL-EPVDKIYFAG 457 >4IVM-B nrPDB Length = 483 Score = 42.4 bits (98), Expect = 5e-04, Method: Compositional matrix adjust. Identities = 35/112 (31%), Positives = 52/112 (46%), Gaps = 20/112 (17%) Query: 7 VVVVGGGISGMAAAKLLHDSGL--NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 VVV+GGGISG+AA+ L + VV++E+ +R+GG ++R +LG + P Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPGGIRPA 70 Query: 65 ---QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYL 113 R L L ELGL++ + P RG P N Y+ Sbjct: 71 GALGARTLLLVSELGLDS---------------EVLPVRGDHPAAQNRFLYV 107 >4DGK-A nrPDB Length = 501 Score = 40.8 bits (94), Expect = 0.001, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 27/45 (60%) Query: 9 VVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKY 53 V+G G G+A A L +G+ V++LE RD+ GGR Y +Q + Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTF 50 >4C5O-A nrPDB Length = 357 Score = 40.4 bits (93), Expect = 0.002, Method: Compositional matrix adjust. Identities = 19/39 (48%), Positives = 26/39 (66%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 + DVVV+GGG SG++A L SGL+ V+L+A GG Sbjct: 2 DSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGG 40 >3X0V-A nrPDB Length = 541 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 26/78 (33%), Positives = 36/78 (46%), Gaps = 7/78 (8%) Query: 7 VVVVGGGISGMAAAKLLHD---SGLNVVVLEARDRVGGRTYT--LRNQKVKYVDLGGSYV 61 V +VG G+SG+ A +L D L + E+ R GGR YT + K Y D+G Sbjct: 10 VCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFTDAKHDYYDIGAMRY 69 Query: 62 G--PTQNRILRLAKELGL 77 P+ R L K G+ Sbjct: 70 PDIPSMKRTFNLFKRTGM 87 >3LOV-A nrPDB Length = 475 Score = 40.0 bits (92), Expect = 0.003, Method: Compositional matrix adjust. Identities = 23/49 (46%), Positives = 34/49 (69%), Gaps = 3/49 (6%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDS--GLNVVVLEARDRVGGRTYTLR 47 MS+K +V+VGGGI+G+AAA + LN+ +LEA +R+GG+ T R Sbjct: 2 MSSK-RLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYR 49 >5NMX-A nrPDB Length = 425 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 25/69 (36%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 V V+G G SG+ AA+ L +G V+V E VGG T+ ++ D Y QN Sbjct: 4 VAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGG-TWNYTDETWMSEDGRPVYSSMYQN 62 Query: 67 RILRLAKEL 75 + L KEL Sbjct: 63 LFVNLPKEL 71 >2IVE-A nrPDB Length = 478 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 20/44 (45%), Positives = 27/44 (61%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT 45 + +V VVGGGISG+A A L G + V+LE+ R+GG T Sbjct: 14 TTGMNVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGT 57 >3KYB-A nrPDB Length = 390 Score = 39.3 bits (90), Expect = 0.005, Method: Compositional matrix adjust. Identities = 18/64 (28%), Positives = 34/64 (53%), Gaps = 1/64 (1%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDLGGSYVGPTQ 65 +++VG G SG + L + G V +++ RD +GG +Y R+ + V + G ++ T Sbjct: 6 ILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHIFHTD 65 Query: 66 NRIL 69 N + Sbjct: 66 NETV 69 >3I6D-A nrPDB Length = 470 Score = 38.5 bits (88), Expect = 0.007, Method: Compositional matrix adjust. Identities = 30/100 (30%), Positives = 51/100 (51%), Gaps = 14/100 (14%) Query: 4 KCDVVVVGGGISGMAAAKLLH------DSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLG 57 K VV++GGGI+G+AAA + + L + ++EA RVGG+ T++ ++ G Sbjct: 5 KKHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKKDGY-IIERG 63 Query: 58 GSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSY 97 + +L K+LGLE L+++ G+SY Sbjct: 64 PDSFLERKKSAPQLVKDLGLE-------HLLVNNATGQSY 96 >3WE0-A nrPDB Length = 580 Score = 38.1 bits (87), Expect = 0.008, Method: Compositional matrix adjust. Identities = 30/79 (37%), Positives = 39/79 (49%), Gaps = 9/79 (11%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVD-----LGGSY 60 +V +VG GI+G+ AA L GL VV EA ++GGR LR+Q D LGG Sbjct: 67 EVAIVGAGIAGLVAAYELMKLGLKPVVYEAS-KMGGR---LRSQAFNGTDGIIAELGGMR 122 Query: 61 VGPTQNRILRLAKELGLET 79 + +LGLET Sbjct: 123 FPVSSTAFYHYVDKLGLET 141 >3UP5-A nrPDB Length = 545 Score = 37.7 bits (86), Expect = 0.012, Method: Compositional matrix adjust. Identities = 20/52 (38%), Positives = 32/52 (61%), Gaps = 5/52 (9%) Query: 1 MSNKC-----DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLR 47 MSN+ D VV+G G++G+ A L++ +G+ V+ +EA + VGG Y R Sbjct: 1 MSNRAKSPALDAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGGTWYWNR 52 >4ZCC-A nrPDB Length = 336 Score = 36.2 bits (82), Expect = 0.031, Method: Compositional matrix adjust. Identities = 22/88 (25%), Positives = 43/88 (48%), Gaps = 2/88 (2%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 + ++G GI+G++AA+ L +G V + + GGR + R+ +D+G Y Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRS-DAGSLDMGAQYFTARDR 63 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKG 94 R K+ + + V+E L+++ G Sbjct: 64 RFATAVKQWQAQGH-VSEWTPLLYNFHG 90 >5ZBC-A nrPDB Length = 451 Score = 36.2 bits (82), Expect = 0.037, Method: Compositional matrix adjust. Identities = 20/67 (29%), Positives = 32/67 (47%), Gaps = 4/67 (5%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDS----GLNVVVLEARDRVGGRTYTLRNQKVKYVDL 56 M + D+ +VG GISG+ A L DS GL++ + + + GGR + ++L Sbjct: 21 MKHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKMLDGKASIEL 80 Query: 57 GGSYVGP 63 G P Sbjct: 81 GAGRYSP 87 >4K22-A nrPDB Length = 365 Score = 35.8 bits (81), Expect = 0.041, Method: Compositional matrix adjust. Identities = 18/34 (52%), Positives = 21/34 (61%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 DV +VGGG+ G+A A L SGL V VLE R Sbjct: 2 QSVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >2CVJ-A nrPDB Length = 180 Score = 35.8 bits (81), Expect = 0.049, Method: Compositional matrix adjust. Identities = 29/69 (42%), Positives = 39/69 (56%), Gaps = 15/69 (21%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG--- 62 DV+VVGGG SG++AA L +GL V+VL+ GGR+ KVK V +Y G Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLD-----GGRS------KVKGVSRVPNYPGLLD 51 Query: 63 -PTQNRILR 70 P+ +LR Sbjct: 52 EPSGEELLR 60 >4C3X-A nrPDB Length = 530 Score = 35.8 bits (81), Expect = 0.050, Method: Compositional matrix adjust. Identities = 17/42 (40%), Positives = 24/42 (57%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT 43 +++CDV+VVG G + A GL +VLE DR GG + Sbjct: 25 TSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGGTS 66 >1I8T-A nrPDB Length = 367 Score = 35.0 bits (79), Expect = 0.070, Method: Compositional matrix adjust. Identities = 15/40 (37%), Positives = 22/40 (55%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT 45 D ++VG G+ G A L V+V+E R+ +GG YT Sbjct: 3 DYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYT 42 >2TMD-A nrPDB Length = 729 Score = 35.0 bits (79), Expect = 0.077, Method: Compositional matrix adjust. Identities = 16/39 (41%), Positives = 26/39 (66%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 NK V++VG G SG AA++L +SG V + + +++GG Sbjct: 388 NKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGG 426 >3MJ4-A nrPDB Length = 397 Score = 35.0 bits (79), Expect = 0.086, Method: Compositional matrix adjust. Identities = 15/43 (34%), Positives = 24/43 (55%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY 44 S D ++VG G +G A+ L SG V++++ R +GG Y Sbjct: 27 SKGFDYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAY 69 >3KKJ-A nrPDB Length = 336 Score = 34.7 bits (78), Expect = 0.099, Method: Compositional matrix adjust. Identities = 21/92 (22%), Positives = 40/92 (43%), Gaps = 1/92 (1%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 + ++G GI+G++AA+ L +G V + + GGR + R+ +D+G Y Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRS-DAGALDMGAQYFTARDR 63 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYP 98 R K+ + + L + G+ P Sbjct: 64 RFATAVKQWQAQGHVAEWTPLLYNFHAGRLSP 95 >4AP1-A nrPDB Length = 549 Score = 34.7 bits (78), Expect = 0.12, Method: Compositional matrix adjust. Identities = 19/43 (44%), Positives = 22/43 (51%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY 44 + DVVVVG GI+G+ A GL V EA VGG Y Sbjct: 19 TTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGGVWY 61 >4N9X-A nrPDB Length = 411 Score = 34.3 bits (77), Expect = 0.12, Method: Compositional matrix adjust. Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 3/45 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE---ARDRVGGRTYTLR 47 DVV+ GGG+ G+A A L SGL + VLE A + G+ + LR Sbjct: 5 DVVIAGGGMVGLALACGLQGSGLRIAVLEKQAAEPQTLGKGHALR 49 >2VOU-A nrPDB Length = 397 Score = 33.9 bits (76), Expect = 0.19, Method: Compositional matrix adjust. Identities = 18/35 (51%), Positives = 24/35 (68%), Gaps = 1/35 (2%) Query: 1 MSNKCD-VVVVGGGISGMAAAKLLHDSGLNVVVLE 34 MS D + VVGG ISG+ AA +L D+G++V V E Sbjct: 1 MSPTTDRIAVVGGSISGLTAALMLRDAGVDVDVYE 35 >3ATQ-A nrPDB Length = 453 Score = 33.5 bits (75), Expect = 0.20, Method: Compositional matrix adjust. Identities = 18/59 (30%), Positives = 34/59 (57%), Gaps = 2/59 (3%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--DRVGGRTYTLRNQKVKYVDLGGSY 60 K DV+++GGG +G +AA L GL +++++++ +R+G + K + LG Y Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCGDAVSKAHFDKLGMPY 64 >2BS2-A nrPDB Length = 660 Score = 33.1 bits (74), Expect = 0.28, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 20/29 (68%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVL 33 CD +V+GGG++G+ AA GL+ +VL Sbjct: 6 CDSLVIGGGLAGLRAAVATQQKGLSTIVL 34 >1DOD-A nrPDB Length = 394 Score = 33.1 bits (74), Expect = 0.31, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 26/41 (63%), Gaps = 2/41 (4%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--DRVGGR 42 K V ++G G SG+ +LLH +G++ V+LE + D V GR Sbjct: 2 KTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGR 42 >3BHF-A nrPDB Length = 390 Score = 33.1 bits (74), Expect = 0.33, Method: Compositional matrix adjust. Identities = 16/37 (43%), Positives = 22/37 (59%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 MS DV+VVG G GMAA L G+ ++++A D Sbjct: 1 MSTHFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFD 37 >4MO2-B nrPDB Length = 368 Score = 32.7 bits (73), Expect = 0.34, Method: Compositional matrix adjust. Identities = 14/40 (35%), Positives = 22/40 (55%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT 45 D ++VG G+ G A + G +V+E R+ +GG YT Sbjct: 3 DYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNCYT 42 >4Y4N-A nrPDB Length = 286 Score = 32.7 bits (73), Expect = 0.35, Method: Compositional matrix adjust. Identities = 16/30 (53%), Positives = 20/30 (66%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DV +VGGG SG+ AA+ + G VVVLE Sbjct: 53 VDVAIVGGGPSGLTAARYIAKEGYKVVVLE 82 >3K30-A nrPDB Length = 690 Score = 32.7 bits (73), Expect = 0.38, Method: Compositional matrix adjust. Identities = 18/36 (50%), Positives = 24/36 (66%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGR 42 V+VVG G SG+ AA+ L G +VV+ EA +GGR Sbjct: 394 VLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGR 429 >3NIX-A nrPDB Length = 421 Score = 32.7 bits (73), Expect = 0.40, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 22/33 (66%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 K DV+V+G G +G AA L++ SG V ++E + Sbjct: 5 KVDVLVIGAGPAGTVAASLVNKSGFKVKIVEKQ 37 >4OVI-A nrPDB Length = 542 Score = 32.7 bits (73), Expect = 0.44, Method: Compositional matrix adjust. Identities = 18/41 (43%), Positives = 24/41 (58%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY 44 + DV+VVG G SG+ A L + G +V V+E VGG Y Sbjct: 16 EVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGGVWY 56 >3LXD-A nrPDB Length = 415 Score = 32.7 bits (73), Expect = 0.44, Method: Compositional matrix adjust. Identities = 18/38 (47%), Positives = 24/38 (63%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT 43 + VV+GGG G+ AA +L G+NV +LEA RV R Sbjct: 154 NAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARV 191 >4Y4M-A nrPDB Length = 290 Score = 32.3 bits (72), Expect = 0.55, Method: Compositional matrix adjust. Identities = 16/31 (51%), Positives = 20/31 (64%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 + DVV+VG G SG+ A+ L G VVVLE Sbjct: 59 EADVVIVGAGPSGLTCARYLAKEGFKVVVLE 89 >4QLO-A nrPDB Length = 360 Score = 32.0 bits (71), Expect = 0.64, Method: Compositional matrix adjust. Identities = 20/77 (25%), Positives = 36/77 (46%), Gaps = 10/77 (12%) Query: 8 VVVGGGISGMAAAKLLHDSGLNV---VVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 +++GG + GM A +LL++ V ++L A R + + + LGG Sbjct: 126 ILIGGSLGGMQAMELLYNQQFEVDKAIILAATSRTSSYSRAFNEIARQAIHLGGK----- 180 Query: 65 QNRILRLAKELGLETYK 81 L +A++LG TY+ Sbjct: 181 --EGLSIARQLGFLTYR 195 >2RGJ-A nrPDB Length = 402 Score = 32.0 bits (71), Expect = 0.68, Method: Compositional matrix adjust. Identities = 13/33 (39%), Positives = 20/33 (60%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVL 33 MS D+++ G GI G++ A LH +G+ V L Sbjct: 1 MSEPIDILIAGAGIGGLSCALALHQAGIGKVTL 33 >5X68-A nrPDB Length = 391 Score = 32.0 bits (71), Expect = 0.71, Method: Compositional matrix adjust. Identities = 27/93 (29%), Positives = 43/93 (46%), Gaps = 14/93 (15%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 V V+GGG+ G A L + V EAR+ T+T + + ++L S+ G Sbjct: 17 VAVIGGGLVGSLQACFLAKRNFQIDVYEAREDTRVATFT----RGRSINLALSHRG---- 68 Query: 67 RILRLAKELGLETYKVNE----VERLIHHVKGK 95 + K +GLE V++ R+IH + GK Sbjct: 69 --RQALKAVGLEDQIVSQGIPMRARMIHSLSGK 99 >4A6N-B nrPDB Length = 398 Score = 31.6 bits (70), Expect = 0.77, Method: Compositional matrix adjust. Identities = 14/39 (35%), Positives = 23/39 (58%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY 44 +V ++GGG G+ AKLL +G++V V E + R + Sbjct: 28 NVAIIGGGPVGLTMAKLLQQNGIDVSVYERDNDREARIF 66 >1V59-A nrPDB Length = 478 Score = 31.6 bits (70), Expect = 0.82, Method: Compositional matrix adjust. Identities = 15/36 (41%), Positives = 21/36 (58%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 DVV++GGG +G AA G N +E R ++GG Sbjct: 7 DVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGG 42 >3IHG-A nrPDB Length = 535 Score = 31.6 bits (70), Expect = 0.85, Method: Compositional matrix adjust. Identities = 14/35 (40%), Positives = 23/35 (65%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 ++ DV+VVG G+ G++ A L G+ V+V+E R Sbjct: 3 DHEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 >4HA6-A nrPDB Length = 508 Score = 31.2 bits (69), Expect = 1.1, Method: Compositional matrix adjust. Identities = 15/33 (45%), Positives = 23/33 (69%), Gaps = 1/33 (3%) Query: 4 KCDVVVVGGGISG-MAAAKLLHDSGLNVVVLEA 35 CD+V+VGGG +G + AA+L D V+++EA Sbjct: 1 NCDIVIVGGGSAGSLLAARLSEDPDSRVLLIEA 33 >3L9K-A nrPDB Length = 97 Score = 31.2 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 19/46 (41%), Positives = 26/46 (56%), Gaps = 2/46 (4%) Query: 309 KDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLAR 354 K GT++++ E PV TLD+T YA +M LA KAR + R Sbjct: 16 KGVVGTIVVNNEGIPVKSTLDNTTTV-QYAGLMS-QLADKARSVVR 59 >4YNU-A nrPDB Length = 571 Score = 31.2 bits (69), Expect = 1.3, Method: Compositional matrix adjust. Identities = 27/82 (32%), Positives = 39/82 (47%), Gaps = 12/82 (14%) Query: 6 DVVVVGGGISGMAAA-KLLHDSGLNVVVLEAR-------DRVGGRTYTLRNQKV---KYV 54 D +VVGGG SG+ A +L + ++V++LEA D Y L +Y Sbjct: 7 DYIVVGGGTSGLVVANRLSENPDVSVLLLEAGASVFNNPDVTNANGYGLAFGSAIDWQYQ 66 Query: 55 DLGGSYVGPTQNRILRLAKELG 76 + SY G Q ++LR K LG Sbjct: 67 SINQSYAGGKQ-QVLRAGKALG 87 >4RPJ-A nrPDB Length = 399 Score = 30.8 bits (68), Expect = 1.3, Method: Compositional matrix adjust. Identities = 16/46 (34%), Positives = 25/46 (54%), Gaps = 1/46 (2%) Query: 1 MSNKCDVVVVGGGISGMA-AAKLLHDSGLNVVVLEARDRVGGRTYT 45 M+ + D+ VVG G G+ A ++ V+VLE R +GG Y+ Sbjct: 4 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYS 49 >5BR7-A nrPDB Length = 393 Score = 30.8 bits (68), Expect = 1.4, Method: Compositional matrix adjust. Identities = 14/44 (31%), Positives = 25/44 (56%), Gaps = 1/44 (2%) Query: 3 NKCDVVVVGGGISGMAAA-KLLHDSGLNVVVLEARDRVGGRTYT 45 + D++VVG G+ G+ A + G V+++E R +GG Y+ Sbjct: 2 SDFDLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYS 45 >4RG3-A nrPDB Length = 548 Score = 30.8 bits (68), Expect = 1.5, Method: Compositional matrix adjust. Identities = 17/44 (38%), Positives = 23/44 (52%), Gaps = 1/44 (2%) Query: 2 SNKCDVVVVGGGISGM-AAAKLLHDSGLNVVVLEARDRVGGRTY 44 ++ D VV+G G G+ A KL H+ GL V + D GG Y Sbjct: 14 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGGTWY 57 >6ER9-A nrPDB Length = 549 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 17/41 (41%), Positives = 21/41 (51%), Gaps = 1/41 (2%) Query: 5 CDVVVVGGGISGMAAAKLLHD-SGLNVVVLEARDRVGGRTY 44 D VV+G G G+ A LH+ GL VV + D GG Y Sbjct: 10 VDAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGGTWY 50 >6DLL-A nrPDB Length = 398 Score = 30.8 bits (68), Expect = 1.6, Method: Compositional matrix adjust. Identities = 11/31 (35%), Positives = 21/31 (67%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 K V ++G G SG+ +LLH +G++ +++E Sbjct: 5 KTQVAIIGAGPSGLLLGQLLHKAGIDNIIVE 35 >5TUK-A nrPDB Length = 408 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 25/96 (26%), Positives = 44/96 (45%), Gaps = 8/96 (8%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLE--ARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 ++V+G GI+G A L G + +++E A R GG +R + G Y Sbjct: 28 ILVIGAGIAGPAVCYWLRRFGFSPILVERCANLRKGGHAVDIRGVAIDLAKSMGIY---- 83 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFR 100 +I + ++ L Y V+ ++H KG+ + FR Sbjct: 84 -KKICNMRTQVELGRY-VDAEGNILHEEKGERFGFR 117 >2GMH-A nrPDB Length = 584 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 16/51 (31%), Positives = 27/51 (52%), Gaps = 6/51 (11%) Query: 1 MSNKCDVVVVGGGISGMAAAKLL------HDSGLNVVVLEARDRVGGRTYT 45 + + DVV+VG G +G++AA L H+ L V ++E +G T + Sbjct: 32 FAEEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLS 82 >1ZOV-A nrPDB Length = 386 Score = 30.4 bits (67), Expect = 2.0, Method: Compositional matrix adjust. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 S DV+VVG G GMAA L G+ +++++ D Sbjct: 1 STHFDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFD 36 >2YQU-A nrPDB Length = 455 Score = 30.0 bits (66), Expect = 2.8, Method: Compositional matrix adjust. Identities = 14/33 (42%), Positives = 21/33 (63%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 ++VVGGG+ G+ + H G V+VLE DR+ Sbjct: 170 LIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRI 202 >4P9S-A nrPDB Length = 848 Score = 29.6 bits (65), Expect = 3.6, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTY 44 ++ + V++GGG G++ A L +G+ +VV+LE + G T+ Sbjct: 22 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 64 >2UYG-A nrPDB Length = 149 Score = 29.3 bits (64), Expect = 4.0, Method: Compositional matrix adjust. Identities = 18/61 (29%), Positives = 25/61 (40%), Gaps = 2/61 (3%) Query: 356 TKEERLKKLCELYAKVLGSLEALEPVHYEEK--NWCEEQYSGGCYTTYFPPGILTQYGRV 413 T E L+ LCE + LG +YE + W ++ + G PG LT Y Sbjct: 24 TTLEELEALCEAWGAELGLGVVFRQTNYEGQLIEWVQQAHQEGFLAIVLNPGALTHYSYA 83 Query: 414 L 414 L Sbjct: 84 L 84 >3RP7-A nrPDB Length = 407 Score = 29.3 bits (64), Expect = 4.2, Method: Compositional matrix adjust. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 +V+G GI G++AA L SG++ V EA Sbjct: 26 AIVIGAGIGGLSAAVALKQSGIDCDVYEA 54 >5L46-A nrPDB Length = 841 Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust. Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTY 44 ++ + V++GGG G++ A L +G+ +VV+LE + G T+ Sbjct: 21 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 63 >5BSW-A nrPDB Length = 541 Score = 29.3 bits (64), Expect = 4.3, Method: Compositional matrix adjust. Identities = 11/29 (37%), Positives = 17/29 (58%) Query: 292 GSVIKCIVYYKEPFWRKKDYCGTMIIDGE 320 G + C+ + KEPF K CGT++ + E Sbjct: 339 GPLAMCLAFAKEPFEIKSGACGTVVRNAE 367 >1GPJ-A nrPDB Length = 404 Score = 29.3 bits (64), Expect = 4.5, Method: Compositional matrix adjust. Identities = 28/108 (25%), Positives = 42/108 (38%), Gaps = 32/108 (29%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 V+VVG G G AK L D G+ V+ V RTY Sbjct: 170 VLVVGAGEMGKTVAKSLVDRGVRAVL------VANRTY---------------------E 202 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLD 114 R + LA++LG E + +E L+ H+ P +P+ ++D Sbjct: 203 RAVELARDLGGEAVRFDE---LVDHLARSDVVVSATAAP--HPVIHVD 245 >2EEZ-A nrPDB Length = 369 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 21/66 (31%), Positives = 29/66 (43%), Gaps = 14/66 (21%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--------DRVGGRTYTLR------NQK 50 VV++GGG G AAK+ G V +L+ D GGR TL + Sbjct: 167 ASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTATEANIKKS 226 Query: 51 VKYVDL 56 V++ DL Sbjct: 227 VQHADL 232 >3NTA-A nrPDB Length = 574 Score = 29.3 bits (64), Expect = 4.7, Method: Compositional matrix adjust. Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 M+N VVGGG G+ + LH G+ +LE D+V Sbjct: 148 MNNVEHATVVGGGFIGLEMMESLHHLGIKTTLLELADQV 186 >4XDY-A nrPDB Length = 338 Score = 29.3 bits (64), Expect = 4.9, Method: Compositional matrix adjust. Identities = 14/28 (50%), Positives = 18/28 (64%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLE 34 + V+G G G A A L DSG+NVV+ E Sbjct: 19 IAVMGYGAQGDAQANCLKDSGINVVIGE 46 >5EQD-A nrPDB Length = 400 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/45 (33%), Positives = 23/45 (51%), Gaps = 1/45 (2%) Query: 2 SNKCDVVVVGGGISGMA-AAKLLHDSGLNVVVLEARDRVGGRTYT 45 + D+ VVG G G+ A + G V+V+E R +GG Y+ Sbjct: 2 TGNFDLFVVGSGFFGLTIAERAATQLGKRVLVIERRPHIGGNAYS 46 >6BRD-A nrPDB Length = 476 Score = 28.9 bits (63), Expect = 5.1, Method: Compositional matrix adjust. Identities = 15/29 (51%), Positives = 20/29 (68%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DV+VVGGG +G+ A L G+ V+VLE Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLE 31 >3UKH-A nrPDB Length = 519 Score = 28.9 bits (63), Expect = 5.2, Method: Compositional matrix adjust. Identities = 17/57 (29%), Positives = 32/57 (56%), Gaps = 1/57 (1%) Query: 6 DVVVVGGGISGMAAAKLLHD-SGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 DV+V+G G +G+ AAK L+ G + +++++ + GG T + D+GG + Sbjct: 8 DVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVTPEGFLYDVGGHVI 64 >3FG2-P nrPDB Length = 404 Score = 28.9 bits (63), Expect = 5.6, Method: Compositional matrix adjust. Identities = 18/45 (40%), Positives = 22/45 (48%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT 45 M +K VVV+G G G+ A GL V V+E RV R T Sbjct: 139 MPDKKHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVT 183 >4JDR-A nrPDB Length = 474 Score = 28.9 bits (63), Expect = 5.9, Method: Compositional matrix adjust. Identities = 16/38 (42%), Positives = 23/38 (60%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 K VVV+G G +G +AA D GL V++E + +GG Sbjct: 6 KTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGG 43 >2VHY-A nrPDB Length = 377 Score = 28.5 bits (62), Expect = 7.9, Method: Compositional matrix adjust. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DVVV+G G +G AA++ + G V VL+ Sbjct: 169 ADVVVIGAGTAGYNAARIANGMGATVTVLD 198 >5OC1-A nrPDB Length = 565 Score = 28.5 bits (62), Expect = 7.9, Method: Compositional matrix adjust. Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%) Query: 6 DVVVVGGGISG-MAAAKLLHDSGLNVVVLEA 35 D VVVG G +G + AA+L D ++V+VLEA Sbjct: 3 DYVVVGAGNAGNVVAARLTEDPDVSVLVLEA 33 >5EZ7-A nrPDB Length = 392 Score = 28.5 bits (62), Expect = 8.3, Method: Compositional matrix adjust. Identities = 13/38 (34%), Positives = 24/38 (63%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT 43 D+++VGGGI+G+ L +G V++E+ GG++ Sbjct: 9 DILIVGGGIAGLWLNARLRRAGYATVLVESASLGGGQS 46 >1ULZ-A nrPDB Length = 451 Score = 28.1 bits (61), Expect = 8.7, Method: Compositional matrix adjust. Identities = 16/33 (48%), Positives = 19/33 (57%), Gaps = 1/33 (3%) Query: 62 GPTQNRILRLAKELGLETYKV-NEVERLIHHVK 93 G RI+R KELG+ T + NEVE HVK Sbjct: 11 GEIAVRIIRACKELGIPTVAIYNEVESTARHVK 43 >6J0Z-C nrPDB Length = 491 Score = 28.1 bits (61), Expect = 9.2, Method: Compositional matrix adjust. Identities = 15/31 (48%), Positives = 21/31 (67%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DVVVVG G +G+ A L +G++VVVL+ Sbjct: 5 DSDVVVVGAGPTGLMLAGELRLAGVSVVVLD 35 >6C6P-A nrPDB Length = 458 Score = 28.1 bits (61), Expect = 9.5, Method: Compositional matrix adjust. Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 1/35 (2%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 N +V++VG G+ G A A +L G V V+E RD Sbjct: 6 NDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE-RD 39 >4USR-A nrPDB Length = 361 Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust. Identities = 13/41 (31%), Positives = 23/41 (56%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 M DV+V+GGG + + A L + L+ ++L+ + GG Sbjct: 4 MPPILDVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGG 44 >4J0E-A nrPDB Length = 320 Score = 28.1 bits (61), Expect = 9.7, Method: Compositional matrix adjust. Identities = 15/54 (27%), Positives = 26/54 (48%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV 54 M N +V +VG G G A++ SG NV++ + + R +Q V ++ Sbjct: 11 MQNIRNVAIVGSGQMGSGIAQVTASSGFNVMLADVNKKALDRAMKAISQSVTHL 64 Searching..................................................done Results from round 2 Score E Sequences producing significant alignments: (bits) Value Sequences used in model and found again: 2BK5-A nrPDB 762 0.0 2BXR-A nrPDB 707 0.0 1O5W-A nrPDB 699 0.0 3RHA-A nrPDB 425 e-119 3KVE-A nrPDB 398 e-111 1REO-A nrPDB 396 e-111 1F8S-A nrPDB 396 e-110 6CR0-A nrPDB 389 e-108 2VVL-G nrPDB 381 e-106 4FWE-A nrPDB 365 e-101 3NK2-X nrPDB 356 1e-98 3L1R-A nrPDB 282 2e-76 2JB2-A nrPDB 238 5e-63 3ABT-A nrPDB 204 1e-52 5L3D-A nrPDB 199 2e-51 3BI4-A nrPDB 154 8e-38 4IV9-A nrPDB 140 1e-33 5MOG-A nrPDB 135 5e-32 4IVM-B nrPDB 105 6e-23 1SEZ-A nrPDB 100 2e-21 4DGK-A nrPDB 80 2e-15 4C5O-A nrPDB 55 7e-08 Sequences not found previously or not previously below threshold: 3WE0-A nrPDB 120 2e-27 3X0V-A nrPDB 111 1e-24 3LOV-A nrPDB 87 2e-17 3I6D-A nrPDB 85 7e-17 2IVE-A nrPDB 70 3e-12 5ZBC-A nrPDB 69 3e-12 3UKH-A nrPDB 69 7e-12 1I8T-A nrPDB 56 4e-08 4ZCC-A nrPDB 54 2e-07 5NMX-A nrPDB 54 2e-07 3KYB-A nrPDB 53 2e-07 5BR7-A nrPDB 53 4e-07 3KKJ-A nrPDB 52 6e-07 4MO2-B nrPDB 51 1e-06 3BHF-A nrPDB 51 1e-06 2YQU-A nrPDB 50 2e-06 3MJ4-A nrPDB 50 3e-06 4RPJ-A nrPDB 50 3e-06 2CVJ-A nrPDB 50 3e-06 5VJ7-A nrPDB 49 7e-06 5JFC-L nrPDB 48 7e-06 2Q7V-A nrPDB 48 8e-06 4OVI-A nrPDB 48 8e-06 4YRY-B nrPDB 48 1e-05 3URH-A nrPDB 47 2e-05 3K30-A nrPDB 47 2e-05 4Y4M-A nrPDB 46 3e-05 4Y4N-A nrPDB 46 4e-05 5Z70-A nrPDB 46 5e-05 3LXD-A nrPDB 46 6e-05 3ATQ-A nrPDB 45 6e-05 1ZOV-A nrPDB 45 7e-05 1RP0-A nrPDB 45 7e-05 3UP5-A nrPDB 45 7e-05 4REP-A nrPDB 44 1e-04 6ER9-A nrPDB 44 2e-04 3FPZ-A nrPDB 44 2e-04 1NAA-A nrPDB 44 2e-04 4GCM-A nrPDB 44 2e-04 4RG3-A nrPDB 43 2e-04 4USR-A nrPDB 43 3e-04 2RGJ-A nrPDB 43 3e-04 5MJK-A nrPDB 43 3e-04 4UIR-A nrPDB 43 3e-04 4AP1-A nrPDB 43 4e-04 5TR3-A nrPDB 43 4e-04 2UZZ-A nrPDB 43 4e-04 2TMD-A nrPDB 43 5e-04 3JSK-A nrPDB 43 5e-04 2VHY-A nrPDB 43 5e-04 5TUM-A nrPDB 42 5e-04 1V59-A nrPDB 42 5e-04 4JDR-A nrPDB 42 6e-04 4C3X-A nrPDB 42 6e-04 4K22-A nrPDB 42 6e-04 2VOU-A nrPDB 42 8e-04 5TWC-A nrPDB 42 9e-04 3NIX-A nrPDB 41 9e-04 1PS9-A nrPDB 41 0.001 3IHG-A nrPDB 41 0.001 4ZN0-A nrPDB 41 0.001 6BRD-A nrPDB 41 0.001 3FG2-P nrPDB 41 0.001 5L46-A nrPDB 41 0.001 1DOD-A nrPDB 41 0.002 3R9U-A nrPDB 41 0.002 2GMH-A nrPDB 41 0.002 4P9S-A nrPDB 41 0.002 2BS2-A nrPDB 40 0.002 4EMJ-A nrPDB 40 0.002 2GV8-A nrPDB 40 0.002 4IA5-A nrPDB 40 0.002 6N7F-A nrPDB 40 0.003 4A6N-B nrPDB 40 0.003 6JDK-A nrPDB 40 0.003 3RP7-A nrPDB 40 0.003 5UTH-A nrPDB 39 0.003 5TUK-A nrPDB 39 0.003 6J0Z-C nrPDB 39 0.004 5YGQ-A nrPDB 39 0.005 3T14-A nrPDB 39 0.005 1NHQ-A nrPDB 39 0.006 1LVL-A nrPDB 39 0.006 5Y77-A nrPDB 39 0.007 5XGV-A nrPDB 38 0.007 6BZ0-A nrPDB 38 0.009 5U8W-A nrPDB 38 0.009 5KOX-A nrPDB 38 0.010 6DLL-A nrPDB 38 0.011 1EBD-A nrPDB 38 0.011 3ISH-A nrPDB 38 0.011 4N9X-A nrPDB 38 0.012 4X4J-A nrPDB 37 0.013 4CBQ-A nrPDB 37 0.013 2QA2-A nrPDB 37 0.014 1KNR-A nrPDB 37 0.014 3LZX-A nrPDB 37 0.014 3NTA-A nrPDB 37 0.015 4B1B-A nrPDB 37 0.016 6AON-A nrPDB 37 0.017 6CMZ-A nrPDB 37 0.019 2A87-A nrPDB 37 0.019 5J7X-A nrPDB 37 0.019 1C0L-A nrPDB 37 0.019 3COX-A nrPDB 37 0.019 5J5Z-A nrPDB 37 0.020 5EZ7-A nrPDB 37 0.020 5UWY-A nrPDB 37 0.022 5X6R-A nrPDB 37 0.024 5ZYN-B nrPDB 37 0.024 3AB1-A nrPDB 37 0.024 3LAD-A nrPDB 37 0.026 6GAR-A nrPDB 36 0.030 6A37-A nrPDB 36 0.033 2E5V-A nrPDB 36 0.035 5TUF-A nrPDB 36 0.035 3SM8-A nrPDB 36 0.035 1FOH-A nrPDB 36 0.035 4K2X-A nrPDB 36 0.036 6C6P-A nrPDB 36 0.037 4MOP-A nrPDB 36 0.037 6BWT-A nrPDB 36 0.038 3QJ4-A nrPDB 36 0.038 6GAS-A nrPDB 36 0.040 4YNU-A nrPDB 36 0.043 2BRY-A nrPDB 36 0.045 4TXK-A nrPDB 36 0.047 4HA6-A nrPDB 36 0.047 3CP8-A nrPDB 36 0.057 2R9Z-A nrPDB 36 0.060 4P2C-A nrPDB 36 0.062 2EQ6-A nrPDB 35 0.066 1GAL-A nrPDB 35 0.083 1DXL-A nrPDB 35 0.095 2ZBW-A nrPDB 35 0.10 5W4C-A nrPDB 34 0.11 6BPY-A nrPDB 34 0.11 4NTC-A nrPDB 34 0.11 5TUL-A nrPDB 34 0.12 3IP1-A nrPDB 34 0.12 5X68-A nrPDB 34 0.12 3CGD-A nrPDB 34 0.14 5KXJ-A nrPDB 34 0.15 2WOP-A nrPDB 34 0.15 2GAG-B nrPDB 34 0.15 3II4-A nrPDB 34 0.16 5XHU-A nrPDB 34 0.21 4Z2R-A nrPDB 33 0.25 1Y56-A nrPDB 33 0.25 4JNQ-A nrPDB 33 0.31 3GDN-A nrPDB 33 0.33 3GMC-A nrPDB 33 0.34 3L8K-A nrPDB 33 0.34 1ZDL-A nrPDB 33 0.39 2EEZ-A nrPDB 33 0.40 4YKF-A nrPDB 32 0.45 1FL2-A nrPDB 32 0.45 3ICS-A nrPDB 32 0.47 1QO8-A nrPDB 32 0.48 1UKV-G nrPDB 32 0.50 4H7U-A nrPDB 32 0.53 5XMJ-A nrPDB 32 0.60 3G5Q-A nrPDB 32 0.69 5ER0-A nrPDB 32 0.78 4Z25-A nrPDB 31 0.92 2QAE-A nrPDB 31 0.95 4U2L-A nrPDB 31 0.97 2YR5-A nrPDB 31 1.0 3HDH-A nrPDB 31 1.0 1F14-A nrPDB 31 1.0 3O0H-A nrPDB 31 1.0 1GPE-A nrPDB 31 1.1 3RED-A nrPDB 31 1.1 2NVK-X nrPDB 31 1.3 3D8X-A nrPDB 31 1.4 5OC1-A nrPDB 31 1.5 6H3G-A nrPDB 31 1.5 5VT6-A nrPDB 31 1.5 5IUJ-C nrPDB 31 1.6 4LDZ-A nrPDB 31 1.6 6DU7-A nrPDB 31 1.7 2CUL-A nrPDB 31 1.7 3IWA-A nrPDB 31 1.7 3CP2-A nrPDB 31 1.7 5EB4-A nrPDB 31 1.8 2YVG-A nrPDB 31 1.9 3G05-A nrPDB 31 1.9 4FK1-A nrPDB 31 1.9 4EIQ-A nrPDB 31 2.0 2BC1-A nrPDB 30 2.2 5NA1-A nrPDB 30 2.6 3OC4-A nrPDB 30 3.0 2WOV-A nrPDB 30 3.4 2HCS-A nrPDB 29 3.5 4P5A-A nrPDB 29 3.7 2QA1-A nrPDB 29 3.8 1VRQ-A nrPDB 29 4.2 5O32-I nrPDB 29 6.1 2XRC-A nrPDB 29 6.1 4BK3-A nrPDB 28 8.2 2ZXH-A nrPDB 28 8.7 >2BK5-A nrPDB Length = 520 Score = 762 bits (1967), Expect = 0.0, Method: Composition-based stats. Identities = 519/520 (99%), Positives = 519/520 (99%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY Sbjct: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR Sbjct: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 Query: 121 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV 180 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV Sbjct: 121 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV 180 Query: 181 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ 240 SALWFLWYVKQCGGTTRI STTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ Sbjct: 181 SALWFLWYVKQCGGTTRIFSTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ 240 Query: 241 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY 300 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY Sbjct: 241 TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY 300 Query: 301 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER 360 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER Sbjct: 301 YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER 360 Query: 361 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR 420 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR Sbjct: 361 LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR 420 Query: 421 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT 480 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT Sbjct: 421 IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT 480 Query: 481 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV 520 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV Sbjct: 481 FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV 520 >2BXR-A nrPDB Length = 527 Score = 707 bits (1825), Expect = 0.0, Method: Composition-based stats. Identities = 376/514 (73%), Positives = 447/514 (86%), Gaps = 2/514 (0%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DVVV+GGGISG++AAKLL + G++V+VLEARDRVGGRTYT+RN+ V YVD+GG+YVGPTQ Sbjct: 15 DVVVIGGGISGLSAAKLLTEYGVSVLVLEARDRVGGRTYTIRNEHVDYVDVGGAYVGPTQ 74 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 NRILRL+KELG+ETYKVN ERL+ +VKGK+YPFRG FPPVWNPI YLD+NN WRT+D+M Sbjct: 75 NRILRLSKELGIETYKVNVSERLVQYVKGKTYPFRGAFPPVWNPIAYLDYNNLWRTIDNM 134 Query: 126 GREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWF 185 G+EIP+DAPW+A A++WD MTMKEL+DK+CWT++A++ A LFVN+ VT+E HEVSALWF Sbjct: 135 GKEIPTDAPWEAQHADKWDKMTMKELIDKICWTKTARRFAYLFVNINVTSEPHEVSALWF 194 Query: 186 LWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENV 245 LWYVKQCGGTTRI S TNGGQERKFVGGSGQVSERIMDLLGD+VKL PV ++DQ+ +N+ Sbjct: 195 LWYVKQCGGTTRIFSVTNGGQERKFVGGSGQVSERIMDLLGDQVKLNHPVTHVDQSSDNI 254 Query: 246 LVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305 ++ETLNHE YE KYVI+AIPPTL KIHF P LP RNQ+I R+P+G+VIKC++YYKE F Sbjct: 255 IIETLNHEHYECKYVINAIPPTLTAKIHFRPELPAERNQLIQRLPMGAVIKCMMYYKEAF 314 Query: 306 WRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLC 365 W+KKDYCG MII+ E+AP++ TLDDTKP+G+ AIMGFILA KA +LA+L KE R KK+C Sbjct: 315 WKKKDYCGCMIIEDEDAPISITLDDTKPDGSLPAIMGFILARKADRLAKLHKEIRKKKIC 374 Query: 366 ELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAG 425 ELYAKVLGS EAL PVHYEEKNWCEEQYSGGCYT YFPPGI+TQYGRV+RQPV RI+FAG Sbjct: 375 ELYAKVLGSQEALHPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIFFAG 434 Query: 426 TETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERH 485 TETAT WSGYMEGAVEAGERAARE+L+ +GK+ E +IW EPES DVPA IT TF ER+ Sbjct: 435 TETATKWSGYMEGAVEAGERAAREVLNGLGKVTEKDIWVQEPESKDVPAVEITHTFWERN 494 Query: 486 LPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVR 519 LPSV GLL++IG +T S TALGF+ +K LL R Sbjct: 495 LPSVSGLLKIIGFST--SVTALGFVLYKYKLLPR 526 >1O5W-A nrPDB Length = 534 Score = 699 bits (1804), Expect = 0.0, Method: Composition-based stats. Identities = 375/513 (73%), Positives = 441/513 (85%), Gaps = 2/513 (0%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DVVV+GGGISG+AAAKLL + +NV+VLEARDRVGGRTYT+RN+ VK+VD+GG+YVGPTQ Sbjct: 23 DVVVIGGGISGLAAAKLLSEYKINVLVLEARDRVGGRTYTVRNEHVKWVDVGGAYVGPTQ 82 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 NRILRL+KELG+ETYKVN ERL+ +VKGK+YPFRG FPPVWNP+ YLD+NN WRTMD+M Sbjct: 83 NRILRLSKELGIETYKVNVNERLVQYVKGKTYPFRGAFPPVWNPLAYLDYNNLWRTMDEM 142 Query: 126 GREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWF 185 G+EIP DAPW+A A+EWD MTMK+L+DK+CWT++A++ A LFVN+ VT+E HEVSALWF Sbjct: 143 GKEIPVDAPWQARHAQEWDKMTMKDLIDKICWTKTAREFAYLFVNINVTSEPHEVSALWF 202 Query: 186 LWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENV 245 LWYV+QCGGT RI S TNGGQERKFVGGSGQVSE+IM LLGD+VKL PV YIDQT +N+ Sbjct: 203 LWYVRQCGGTARIFSVTNGGQERKFVGGSGQVSEQIMGLLGDKVKLSSPVTYIDQTDDNI 262 Query: 246 LVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPF 305 +VETLNHE YE KYVISAIPP L KIHF P LP RNQ+I R+P+G+VIKC+VYYKE F Sbjct: 263 IVETLNHEHYECKYVISAIPPILTAKIHFKPELPPERNQLIQRLPMGAVIKCMVYYKEAF 322 Query: 306 WRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLC 365 W+KKDYCG MII+ EEAP+A TLDDTKP+G+ AIMGFILA KA +LA+L K+ R +K+C Sbjct: 323 WKKKDYCGCMIIEDEEAPIAITLDDTKPDGSLPAIMGFILARKADRLAKLHKDIRKRKIC 382 Query: 366 ELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAG 425 ELYAKVLGS EAL PVHYEEKNWCEEQYSGGCYT YFPPGI+TQYGRV+RQPV RIYFAG Sbjct: 383 ELYAKVLGSQEALYPVHYEEKNWCEEQYSGGCYTAYFPPGIMTQYGRVIRQPVGRIYFAG 442 Query: 426 TETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERH 485 TETAT WSGYMEGAVEAGERAARE+L+A+GK+ + +IW EPES DVPA IT TFLER+ Sbjct: 443 TETATQWSGYMEGAVEAGERAAREVLNALGKVAKKDIWVEEPESKDVPAIEITHTFLERN 502 Query: 486 LPSVPGLLRLIGLTTIFSATALGFLAHKRGLLV 518 LPSVPGLL++ G++T S L F+ +K L Sbjct: 503 LPSVPGLLKITGVST--SVALLCFVLYKIKKLP 533 >3RHA-A nrPDB Length = 482 Score = 425 bits (1091), Expect = e-119, Method: Composition-based stats. Identities = 148/451 (32%), Positives = 221/451 (49%), Gaps = 9/451 (1%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 DVV+VG G SG+ AA+ L +GL+V VLEARDRVGGRT+T +++GG +V P Sbjct: 8 RDVVIVGAGPSGLTAARELKKAGLSVAVLEARDRVGGRTWT-DTIDGAMLEIGGQWVSPD 66 Query: 65 QNRILRLAKELGLETY-KVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMD 123 Q ++ L ELGL+ Y + + E + GK + G PV N T + + +D Sbjct: 67 QTVLMELLDELGLKMYSRYRDGESVYIGADGKRTQYTGDTFPV-NETTKAEMDKLVAILD 125 Query: 124 DMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFV-NLCVTAETHEVSA 182 ++ EI PW P A E D ++ L + E A LF+ +T H SA Sbjct: 126 ELAAEIGPTEPWAHPKARELDTISFHHWLRQNSNDEEACNNIGLFIAGGMLTKPAHAFSA 185 Query: 183 LWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTR 242 L + G + + + + +++ +GG QVS LGD V L PV I Sbjct: 186 LQAVLMAASAGSFSHL-TDEDFILDKRVIGGMQQVSLLQAAELGDDVVLNSPVRTIK-WD 243 Query: 243 ENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYK 302 EN + A++VI A+PP L ++ F+PPLP ++QM LG VIK Y Sbjct: 244 ENGVSVVSERATVNARFVIMAVPPNLYSRVSFDPPLPRRQHQMHQHQSLGLVIKVHAVYD 303 Query: 303 EPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLK 362 PFWR++ GT G A V D+T + ++GF+ KA + L+ E+R K Sbjct: 304 TPFWREEGLSGTGFSAG--ALVQEVYDNTNHGDSRGTLVGFVSDEKADAVFELSAEDRKK 361 Query: 363 KLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIY 422 + E A LG AL P Y E +W E+++ G Y + + G L +YG+ V IY Sbjct: 362 AILESIAGFLGDK-ALTPEVYYESDWGSEEWTRGAYASSYDLGGLHRYGKDQHANVGPIY 420 Query: 423 FAGTETATHWSGYMEGAVEAGERAAREILHA 453 ++ ++ A +++GAV G+ A I+ A Sbjct: 421 WSSSDLAAEGYQHVDGAVRMGQATAARIVEA 451 >3KVE-A nrPDB Length = 486 Score = 398 bits (1023), Expect = e-111, Method: Composition-based stats. Identities = 115/482 (23%), Positives = 186/482 (38%), Gaps = 59/482 (12%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSY 60 SN VVVVG G+SG++AA +L +G V VLEA +R GGR T RN K + +LG Sbjct: 31 SNPKHVVVVGAGMSGLSAAYVLAGAGHKVTVLEASERAGGRVRTHRNSKEGWYANLGPMR 90 Query: 61 VGPTQNRILR------------LAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPV-- 106 + P ++RI+R ++E Y + + + + V + P P Sbjct: 91 I-PEKHRIVREYIRKFGLNLNEFSQENDNAWYFIKNIRKRVGEVNKDPGLLKYPVKPSEE 149 Query: 107 WNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLAT 166 L + + D+ R S + ++D + KE L K + Sbjct: 150 GKSAGQLYEESLGSAVKDLKRTNCS------YILNKYDTYSTKEYLIK--EGNLSPGAVD 201 Query: 167 LFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLG 226 + +L + VS + L + R + VGG Q+ + + Sbjct: 202 MIGDLLNEDSGYYVSFIESLKHDDIFAYEKRF---------DEIVGGMDQLPTSMYRAIE 252 Query: 227 DRVKLERPVIYIDQTRENVLVET----LNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMR 282 ++VK VI I Q V V + A YVI +I F PPLP + Sbjct: 253 EKVKFNARVIKIQQNANQVTVTYQTPEKDTSSNTADYVIVCTTSRAARRIQFEPPLPPKK 312 Query: 283 NQMITRVPLGSVIKCIVYYKEPFWRKKD-YCGTMIIDGEEAPVAYTLDDTKPEGNYAAIM 341 + V S K + FW + G D + Y P N++ + Sbjct: 313 QHALRSVHYRSGTKIFLTCSSKFWEDDGIHGGKSTTDLPSRFIYY------PNHNFSTGV 366 Query: 342 GFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEE----------KNWCEE 391 G I+A+ A + + K ++ V L + + EE + W + Sbjct: 367 GVIIAYGIGDDANFFQALKFKDCADI---VFNDLSLIHQLPKEEIQSFCYPSMIQKWSLD 423 Query: 392 QYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREIL 451 +Y+ G TT F P ++ L P RI+FAG TA G+++ +++G AAR++ Sbjct: 424 KYAMGAITT-FTPYQFQRFSEALTAPQGRIFFAGEYTA-EAHGWIDSTIKSGLTAARDVN 481 Query: 452 HA 453 A Sbjct: 482 RA 483 >1REO-A nrPDB Length = 486 Score = 396 bits (1018), Expect = e-111, Method: Composition-based stats. Identities = 118/482 (24%), Positives = 193/482 (40%), Gaps = 59/482 (12%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSY 60 SN VVVVG G+SG++AA +L +G V VLEA +R GGR T RN K + +LG Sbjct: 31 SNPKHVVVVGAGMSGLSAAYVLSGAGHQVTVLEASERAGGRVRTYRNDKEDWYANLGPMR 90 Query: 61 VGPTQNRILR-LAKELGLE-----------TYKVNEVERLIHHVKGKSYPFRGPFPPV-- 106 + P ++RI+R ++ GL+ Y + + + + VK + P P Sbjct: 91 L-PEKHRIVREYIRKFGLQLNEFSQENDNAWYFIKNIRKRVGEVKKDPGVLKYPVKPSEE 149 Query: 107 WNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLAT 166 L + + ++++ R S + ++D + KE L L + Sbjct: 150 GKSAGQLYEESLGKVVEELKRTNCS------YILNKYDTYSTKEYL--LKEGNLSPGAVD 201 Query: 167 LFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLG 226 + +L + VS L + R + VGG ++ + + Sbjct: 202 MIGDLMNEDSGYYVSFPESLRHDDIFAYEKRF---------DEIVGGMDKLPTSMYRAIE 252 Query: 227 DRVKLERPVIYIDQTRENVLVETLNH----EMYEAKYVISAIPPTLGMKIHFNPPLPMMR 282 ++V L VI I + E V V A YVI +I F PPLP + Sbjct: 253 EKVHLNAQVIKIQKNAEKVTVVYQTPAKEMASVTADYVIVCTTSRATRRIKFEPPLPPKK 312 Query: 283 NQMITRVPLGSVIKCIVYYKEPFWRKKD-YCGTMIIDGEEAPVAYTLDDTKPEGNYAAIM 341 + V S K + + FW + + G D + Y P N+ + + Sbjct: 313 AHALRSVHYRSGTKIFLTCTKKFWEDEGIHGGKSTTDLPSRFIYY------PNHNFTSGV 366 Query: 342 GFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEE----------KNWCEE 391 G I+A+ A + K ++ V+ L + + EE + W + Sbjct: 367 GVIIAYGIGDDANFFQALDFKDCADI---VINDLSLIHQLPREEIQTFCYPSMIQKWSLD 423 Query: 392 QYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREIL 451 +Y+ G TT F P + L VDRIYFAG TA G+++ +++G RAAR++ Sbjct: 424 KYAMGGITT-FTPYQFQHFSESLTASVDRIYFAGEHTA-EAHGWIDSTIKSGLRAARDVN 481 Query: 452 HA 453 A Sbjct: 482 RA 483 >1F8S-A nrPDB Length = 498 Score = 396 bits (1017), Expect = e-110, Method: Composition-based stats. Identities = 112/477 (23%), Positives = 187/477 (39%), Gaps = 53/477 (11%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSY 60 SN VV+VG G++G++AA +L +G V VLEA +R GGR T RN++ + +LG Sbjct: 31 SNPKHVVIVGAGMAGLSAAYVLAGAGHQVTVLEASERPGGRVRTYRNEEAGWYANLGPMR 90 Query: 61 VGPTQNRILR------------LAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPP--V 106 + P ++RI+R ++E Y + + + + VK + P P Sbjct: 91 L-PEKHRIVREYIRKFDLRLNEFSQENDNAWYFIKNIRKKVGEVKKDPGLLKYPVKPSEA 149 Query: 107 WNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLAT 166 L + + ++++ R S + ++D + KE L K + + Sbjct: 150 GKSAGQLYEESLGKVVEELKRTNCS------YILNKYDTYSTKEYLIK--EGDLSPGAVD 201 Query: 167 LFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLG 226 + +L + VS + L + R + V G ++ + + Sbjct: 202 MIGDLLNEDSGYYVSFIESLKHDDIFAYEKRF---------DEIVDGMDKLPTAMYRDIQ 252 Query: 227 DRVKLERPVIYIDQTRENVLV--ETLNHEM--YEAKYVISAIPPTLGMKIHFNPPLPMMR 282 D+V VI I Q + V V ETL+ E A YVI I FNPPL + Sbjct: 253 DKVHFNAQVIKIQQNDQKVTVVYETLSKETPSVTADYVIVCTTSRAVRLIKFNPPLLPKK 312 Query: 283 NQMITRVPLGSVIKCIVYYKEPFWRKKD-YCGTMIIDGEEAPVAYTLDDTKPEGNYAAIM 341 + V S K + FW + G D + Y P N+ + Sbjct: 313 AHALRSVHYRSGTKIFLTCTTKFWEDDGIHGGKSTTDLPSRFIYY------PNHNFTNGV 366 Query: 342 GFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEE-------KNWCEEQYS 394 G I+A+ A + K ++ L + L + + W ++Y+ Sbjct: 367 GVIIAYGIGDDANFFQALDFKDCADIVFNDLSLIHQLPKKDIQSFCYPSVIQKWSLDKYA 426 Query: 395 GGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREIL 451 G TT F P + L RIYFAG TA G+++ +++G RAAR++ Sbjct: 427 MGGITT-FTPYQFQHFSDPLTASQGRIYFAGEYTA-QAHGWIDSTIKSGLRAARDVN 481 >6CR0-A nrPDB Length = 440 Score = 389 bits (998), Expect = e-108, Method: Composition-based stats. Identities = 110/455 (24%), Positives = 192/455 (42%), Gaps = 34/455 (7%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D +VVG G SG+ AA+ L G +V+++EAR R+GGRT+ + N + V++GG+ V Q Sbjct: 10 DAIVVGAGFSGLVAARELSAQGRSVLIIEARHRLGGRTHVV-NFLGRPVEIGGAGVHWCQ 68 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLD--HNNFWRTMD 123 + + G +K + L K+Y + P D + + Sbjct: 69 PHVFAEMQRYGF-GFKEAPLADL-----DKAYMVFADGQKIDVPPATFDEEYTTAFEKFC 122 Query: 124 DMGREIPSD--APWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCV--TAETHE 179 RE+ +P D ++ ++ L+ L E QLA++ L + A T E Sbjct: 123 SRSRELFPRPYSPLDNHEVSNLDGVSARDHLESLGLNEL--QLASMNAELTLYGGAPTTE 180 Query: 180 VSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYID 239 +S F+ + T I+ T+ + GG+ + + I D + PV + Sbjct: 181 LSYPSFVKFHALASWDT--ITFTDSEKRYHVQGGTNALCQAIFDDCRADSEFGVPVEAVA 238 Query: 240 QTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIV 299 QT V V + ++ A + +P + + F PPLP + I + + V Sbjct: 239 QTDNGVTVTLADKRVFRALTCVLTLPTKVYADVRFEPPLPPEKRAFIEHAEMADGAELYV 298 Query: 300 YYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEE 359 + ++ +C + A Y DD I+ + ++ L E Sbjct: 299 HVRQNLGNTFTFCDDP--NPFNAVQTYAYDD-----ELGTILKITIGRQS-----LINLE 346 Query: 360 RLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVD 419 + K+ G +E LE + Y NW ++Y+ Y G ++Y + + +P + Sbjct: 347 NFDAIAAEIRKIHGDVEVLEALPY---NWAMDEYARTSYPA-MRKGWFSRY-KDMAKPEN 401 Query: 420 RIYFAGTETATHWSGYMEGAVEAGERAAREILHAM 454 R++FAG+ TA W Y++GA+E+G R REI H M Sbjct: 402 RLFFAGSATADGWHEYIDGAIESGIRVGREIRHFM 436 >2VVL-G nrPDB Length = 495 Score = 381 bits (978), Expect = e-106, Method: Composition-based stats. Identities = 113/481 (23%), Positives = 193/481 (40%), Gaps = 54/481 (11%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGP 63 DV+V+GGG G+ A + L +G ++LEARDR+GGR+++ Y ++GG++V Sbjct: 39 PWDVIVIGGGYCGLTATRDLTVAGFKTLLLEARDRIGGRSWSSNIDGYPY-EMGGTWVHW 97 Query: 64 TQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPF-RG--PFPPVWNPITYLDH----- 115 Q+ + R +H+ S+ F RG F NP T Sbjct: 98 HQSHVWREITRY------------KMHNALSPSFNFSRGVNHFQLRTNPTTSTYMTHEAE 145 Query: 116 --------NNFWRTMDDMGREI--PSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLA 165 + F GR + + P ++D M+ E +D++ S + + Sbjct: 146 DELLRSALHKFTNVDGTNGRTVLPFPHDMFYVPEFRKYDEMSYSERIDQIRDELSLNERS 205 Query: 166 TL--FVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMD 223 +L F+ LC S FL + G T + + KF G + R + Sbjct: 206 SLEAFILLCSGGTLENSSFGEFLHWWAMSGYTYQ--GCMDCLMSYKFKDGQSAFARRFWE 263 Query: 224 LLGDRVKLER----PVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLP 279 +L PV + R+ V + + AK V+ IP + I F+P L Sbjct: 264 EAAGTGRLGYVFGCPVRSVVNERDAARVTARDGREFVAKRVVCTIPLNVLSTIQFSPALS 323 Query: 280 MMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTL-DDTKPEGNYA 338 R I+ + G V C + E KD I + Y + D T P GN Sbjct: 324 TER---ISAMQAGHVSMCTKVHAEV--DNKDMRSWTGIAYPFNKLCYAIGDGTTPAGNTH 378 Query: 339 AIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCY 398 + A+ + + E LK + +L G + NW +++++ G + Sbjct: 379 LVCFGTDANHIQPDEDV--RETLKAVGQLAPGTFGVKRLV------FHNWVKDEFAKGAW 430 Query: 399 TTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIP 458 + PG++++ + LR+ + FA ++ A W +++GA+E G RAAR +L +G Sbjct: 431 -FFSRPGMVSECLQGLREKHGGVVFANSDWALGWRSFIDGAIEEGTRAARVVLEELGTKR 489 Query: 459 E 459 E Sbjct: 490 E 490 >4FWE-A nrPDB Length = 796 Score = 365 bits (936), Expect = e-101, Method: Composition-based stats. Identities = 107/462 (23%), Positives = 193/462 (41%), Gaps = 41/462 (8%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV-GP 63 V+++G G +G+AAA+ LH+ G+ V VLEA+DR+GGR + ++ K V G V G Sbjct: 357 KSVIIIGAGPAGLAAARQLHNFGIKVTVLEAKDRIGGRVWDDKSFKGVTVGRGAQIVNGC 416 Query: 64 TQNRILRLAKELGLETYKVNEVERLIHH---VKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 N + + ++LG+ +K E LI + + R F +N + LD + WR Sbjct: 417 INNPVALMCEQLGISMHKFGERCDLIQEGGRITDPTIDKRMDFH--FNAL--LDVVSEWR 472 Query: 121 TMDDMGREIP----SDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAE 176 +++P + +KA + E + EL ++ Q + + Sbjct: 473 KDKTQLQDVPLGEKIEEIYKAFIKES--GIQFSELEGQVL------QFHLSNLEYACGSN 524 Query: 177 THEVSALWFLW--YVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERP 234 H+VSA + + Q G +++ G + E++ + G ++L+ P Sbjct: 525 LHQVSARSWDHNEFFAQFAGDHTLLTP-----------GYSVIIEKLAE--GLDIQLKSP 571 Query: 235 VIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMK--IHFNPPLPMMRNQMITRVPLG 292 V ID + + V V T + Y A+ V+ +P L K I FNPPL + + I + G Sbjct: 572 VQCIDYSGDEVQVTTTDGTGYSAQKVLVTVPLALLQKGAIQFNPPLSEKKMKAINSLGAG 631 Query: 293 SVIKCIVYYKEPFWRKK----DYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHK 348 + K + + FW K D+ G + + + D P+ ++ +M I Sbjct: 632 IIEKIALQFPYRFWDSKVQGADFFGHVPPSASKRGLFAVFYDMDPQKKHSVLMSVIAGEA 691 Query: 349 ARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILT 408 + L ++ L++ ++ E +P Y W + + Y+ G Sbjct: 692 VASVRTLDDKQVLQQCMATLRELFKEQEVPDPTKYFVTRWSTDPWIQMAYSFVKTGGSGE 751 Query: 409 QYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREI 450 Y + ++FAG T H+ + GA +G R A +I Sbjct: 752 AYDIIAEDIQGTVFFAGEATNRHFPQTVTGAYLSGVREASKI 793 >3NK2-X nrPDB Length = 431 Score = 356 bits (913), Expect = 1e-98, Method: Composition-based stats. Identities = 106/456 (23%), Positives = 184/456 (40%), Gaps = 45/456 (9%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK--YVDLGGSYVGP 63 D +VVGGG SG+ AA+ L ++G V++LE +R+GGR Y+ ++ V V++GG+Y+ Sbjct: 3 DAIVVGGGFSGLKAARDLTNAGKKVLLLEGGERLGGRAYSRESRNVPGLRVEIGGAYLHR 62 Query: 64 -TQNRILRLAKELGLETYKVNEVERLIHHVK----GKSYPFRGPFPPVWNPITYLDHNNF 118 R+ G+ T +E H + +++P G TY + Sbjct: 63 KHHPRLAAELDRYGIPTAAASEFTSFRHRLGPTAVDQAFPIPGSEAVAVEAATYTLLRDA 122 Query: 119 WRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETH 178 R + G E PL E +DKL ++Q + + Sbjct: 123 HRIDLEKGLENQDLEDLDIPL---------NEYVDKLDLPPVSRQFLLAWAWNMLGQPAD 173 Query: 179 EVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYI 238 + SALW L V + + + + F GS + + + + + ++L+ V I Sbjct: 174 QASALWMLQLVAAHHYSILGVVLS---LDEVFSNGSADLVDAMSQEIPE-IRLQTVVTGI 229 Query: 239 DQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCI 298 DQ+ + V V + ++A VI A P +I F P LP R +I G +K + Sbjct: 230 DQSGDVVNVTVKDGHAFQAHSVIVATPMNTWRRIVFTPALPERRRSVIEEGHGGQGLKIL 289 Query: 299 VYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPE-GNYAAIMGFILAHKARKLARLTK 357 ++ + G EA + D P +Y + + R L T Sbjct: 290 IHVR----------------GAEAGIECVGDGIFPTLYDYCEV-----SESERLLVAFTD 328 Query: 358 EERLK--KLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLR 415 + + VL L +E + + +W + G + G ++ + L Sbjct: 329 SGSFDPTDIGAVKDAVLYYLPEVEVLGIDYHDWIADPLFEGPWVAP-RVGQFSRVHKELG 387 Query: 416 QPVDRIYFAGTETATHWSGYMEGAVEAGERAAREIL 451 +P RI+F G++ + + GY+EGA+E E A IL Sbjct: 388 EPAGRIHFVGSDVSLEFPGYIEGALETAECAVNAIL 423 >3L1R-A nrPDB Length = 478 Score = 282 bits (721), Expect = 2e-76, Method: Composition-based stats. Identities = 86/468 (18%), Positives = 180/468 (38%), Gaps = 30/468 (6%) Query: 7 VVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 V+VVG G+SG++AAK L ++G+ ++++LEA D +GGR + + V+LG ++V Sbjct: 7 VIVVGAGMSGISAAKRLSEAGITDLLILEATDHIGGRMHKTNFAGIN-VELGANWVEGVN 65 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 + + T K+ ++ Y G ++ + M + Sbjct: 66 GGKMNPIWPIVNSTLKLRNFRSDFDYLAQNVYKEDGGVYDEDYVQKRIELADSVEEMGEK 125 Query: 126 GREIPS---DAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVN------LCVTAE 176 + + + + F L T Sbjct: 126 LSATLHASGRDDMSILAMQRLNEHQPNGPATPVDMVVDYYKFDYEFAEPPRVTSLQNTVP 185 Query: 177 THEVS-ALWFLWYVK-QCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERP 234 S +++V Q G + GQ K SG++ + R++L + Sbjct: 186 LATFSDFGDDVYFVADQRGYEAVVYYL--AGQYLKTDDKSGKIVDP-------RLQLNKV 236 Query: 235 VIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGM--KIHFNPPLPMMRNQMITRVPLG 292 V I + V V+T ++ +Y A YV+ + + I F P LP + + I + + Sbjct: 237 VREIKYSPGGVTVKTEDNSVYSADYVMVSASLGVLQSDLIQFKPKLPTWKVRAIYQFDMA 296 Query: 293 SVIKCIVYYKEPFW---RKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKA 349 + + FW + +++ V + P+ N ++ + ++ Sbjct: 297 VYTMIFLKFPRKFWPEGKGREFFLYASSRRGYYGVWQEFEKQYPDAN--VLLVTVTDEES 354 Query: 350 RKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQ 409 R++ + + E+ ++ ++ K+ + + W +++ G ++ + P G+ Sbjct: 355 RRIEQQSDEQTKAEIMQVLRKMFPGKDVPDATDILVPRWWSDRFYKGTFSNW-PVGVNRY 413 Query: 410 YGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKI 457 LR PV R+YF G T+ H++GY+ GA +G +A +++ K Sbjct: 414 EYDQLRAPVGRVYFTGEHTSEHYNGYVHGAYLSGIDSAEILINCAQKK 461 >2JB2-A nrPDB Length = 489 Score = 238 bits (607), Expect = 5e-63, Method: Composition-based stats. Identities = 94/496 (18%), Positives = 170/496 (34%), Gaps = 76/496 (15%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRN----------------QK 50 VVV+GGG +G+ +A L +G V VLEAR R GGR +T R + Sbjct: 14 VVVLGGGPAGLCSAFELQKAGYKVTVLEARTRPGGRVWTARGGSEETDLSGETQKCTFSE 73 Query: 51 VKYVDLGGSYVGPTQNRILRLAKELG--LETYKVNEVERLIHHVKGKSYPFRGPFPPVWN 108 + ++G + + P + L +ELG ++ + +++ S + Sbjct: 74 GHFYNVGATRI-PQSHITLDYCRELGVEIQGFGNQNANTFVNYQSDTSLSGQSVTYRAAK 132 Query: 109 PITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLF 168 T+ + + D G L+ E D + E L + Sbjct: 133 ADTFGYMSELLKKATDQGA-------LDQVLSRE-DKDALSEFLSDFGDLSDDGRYLGSS 184 Query: 169 VNLCVTAETHEVSALWFLWYVKQ---------------CGGTTRIISTTNGGQERKFVGG 213 + ++ G ++ T VGG Sbjct: 185 RRGYDSEPGAGLNFGTEKKPFAMQEVIRSGIGRNFSFDFGYDQAMMMFTP-------VGG 237 Query: 214 SGQVSERIMDLLG-DRVKLERPVIYIDQTRENVLVETL---NHEMYEAKYVISAIPPTLG 269 ++ D +G D + V + E V VE + + A Y I IPP L Sbjct: 238 MDRIYYAFQDRIGTDNIVFGAEVTSMKNVSEGVTVEYTAGGSKKSITADYAICTIPPHLV 297 Query: 270 MKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKD--YCGTMIIDGEEAPVAYT 327 ++ N P ++ + S K + Y +W +D Y G D + + + + Sbjct: 298 GRLQNNLPGDVL--TALKAAKPSSSGKLGIEYSRRWWETEDRIYGGASNTDKDISQIMFP 355 Query: 328 LDDTKPEGNYAAIMGFILAH-----KARKLARLTKEERLKKLCELYAKVLGSLEALEPVH 382 D +Y + G ++A+ + LT +RL K +++ G + Sbjct: 356 YD------HYNSDRGVVVAYYSSGKRQEAFESLTHRQRLAKAIAEGSEIHGEKYTRDISS 409 Query: 383 YEEKNWCEEQYSGGCYTTYFPPGILT------QYGRVLRQPVDRIYFAGTETATHWSGYM 436 +W +YS + + G +Y ++L +PVD+IYFAG + + + Sbjct: 410 SFSGSWRRTKYSESAWANWAGSGGSHGGAATPEYEKLL-EPVDKIYFAGDHLS-NAIAWQ 467 Query: 437 EGAVEAGERAAREILH 452 GA+ + I Sbjct: 468 HGALTSARDVVTHIHE 483 >3ABT-A nrPDB Length = 662 Score = 204 bits (518), Expect = 1e-52, Method: Composition-based stats. Identities = 61/417 (14%), Positives = 132/417 (31%), Gaps = 60/417 (14%) Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYL------DHNNFWR 120 + KEL + + E + +H ++ + PP +L D + Sbjct: 265 KTQEELKELLNKMVNLKEKIKELHQQYKEASEVK---PPRDITAEFLVKSKHRDLTALCK 321 Query: 121 TMDDMGREIPS-DAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHE 179 D++ + + A ++ + ++ + Sbjct: 322 EYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILD------WHFANLEFANATPLST 375 Query: 180 VSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYID 239 +S L + Q G G V + + G +KL V + Sbjct: 376 LS----LKHWDQ------DDDFEFTGSHLTVRNGYSCVPVALAE--GLDIKLNTAVRQVR 423 Query: 240 QTRENVLVETLNHEM------YEAKYVISAIPPTLGMK----IHFNPPLPMMRNQMITRV 289 T V +N Y+ V+ +P + + + F PPLP + + R+ Sbjct: 424 YTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRM 483 Query: 290 PLGSVIKCIVYYKEPFWRK----KDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFIL 345 G++ K ++ + FW + G+ E + + L ++ + Sbjct: 484 GFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKA------PILLALVA 537 Query: 346 AHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPG 405 A + ++ + + + + + GS +P W + ++ G Y+ Sbjct: 538 GEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSYSYVAAGS 597 Query: 406 ILTQYGRVLR------------QPVDRIYFAGTETATHWSGYMEGAVEAGERAAREI 450 Y + + QP+ R++FAG T ++ + GA+ +G R A I Sbjct: 598 SGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRI 654 Score = 96.0 bits (237), Expect = 3e-20, Method: Composition-based stats. Identities = 52/175 (29%), Positives = 84/175 (48%), Gaps = 12/175 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSYV-GP 63 V+++G G+SG+AAA+ L G++V +LEARDRVGGR T R K YV DLG V G Sbjct: 109 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGL 166 Query: 64 TQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGP------FPPVWNPITYLDHNN 117 N + ++K++ +E K+ + + ++ G++ P F + +YL H Sbjct: 167 GGNPMAVVSKQVNMELAKIKQ-KCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQL 225 Query: 118 FWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWT-ESAKQLATLFVNL 171 + +++ + L E+ E K+ T E K+L VNL Sbjct: 226 DFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNL 280 >5L3D-A nrPDB Length = 852 Score = 199 bits (506), Expect = 2e-51, Method: Composition-based stats. Identities = 70/447 (15%), Positives = 144/447 (32%), Gaps = 71/447 (15%) Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYL------DHNNFWR 120 + KEL + + E + +H ++ + PP +L D + Sbjct: 436 KTQEELKELLNKMVNLKEKIKELHQQYKEASEVK---PPRDITAEFLVKSKHRDLTALCK 492 Query: 121 TMDDMGREIPS-DAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHE 179 D++ + + A ++ + ++ + Sbjct: 493 EYDELAETQGKLEEKLQELEANPPSDVYLSSRDRQILD------WHFANLEFANATPLST 546 Query: 180 VSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYID 239 +S L + Q G G V + + G +KL V + Sbjct: 547 LS----LKHWDQ------DDDFEFTGSHLTVRNGYSCVPVALAE--GLDIKLNTAVRQVR 594 Query: 240 QTRENVLVETLNHEM------YEAKYVISAIPPTLGMK----IHFNPPLPMMRNQMITRV 289 T V +N Y+ V+ +P + + + F PPLP + + R+ Sbjct: 595 YTASGCEVIAVNTRSTSQTFIYKCDAVLCTLPLGVLKQQPPAVQFVPPLPEWKTSAVQRM 654 Query: 290 PLGSVIKCIVYYKEPFWRK----KDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFIL 345 G++ K ++ + FW + G+ E + + L ++ + Sbjct: 655 GFGNLNKVVLCFDRVFWDPSVNLFGHVGSTTASRGELFLFWNLYKA------PILLALVA 708 Query: 346 AHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPG 405 A + ++ + + + + + GS +P W + ++ G ++ Sbjct: 709 GEAAGIMENISDDVIVGRCLAILKGIFGSSAVPQPKETVVSRWRADPWARGSHSYVAAGS 768 Query: 406 ILTQYGRVLR------------QPVDRIYFAGTETATHWSGYMEGAVEAGERAAREI--- 450 Y + + QP+ R++FAG T ++ + GA+ +G R A I Sbjct: 769 SGNDYDLMAQPITPGPSIPGAPQPIPRLFFAGEHTIRNYPATVHGALLSGLREAGRIADQ 828 Query: 451 -LHAMGKIPEDEIWQSEPESVDVPAQP 476 L AM +P Q+ P VPAQ Sbjct: 829 FLGAMYTLPR----QATP---GVPAQQ 848 Score = 95.3 bits (235), Expect = 6e-20, Method: Composition-based stats. Identities = 52/175 (29%), Positives = 84/175 (48%), Gaps = 12/175 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV-DLGGSYV-GP 63 V+++G G+SG+AAA+ L G++V +LEARDRVGGR T R K YV DLG V G Sbjct: 280 KVIIIGSGVSGLAAARQLQSFGMDVTLLEARDRVGGRVATFR--KGNYVADLGAMVVTGL 337 Query: 64 TQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGP------FPPVWNPITYLDHNN 117 N + ++K++ +E K+ + + ++ G++ P F + +YL H Sbjct: 338 GGNPMAVVSKQVNMELAKIKQ-KCPLYEANGQAVPKEKDEMVEQEFNRLLEATSYLSHQL 396 Query: 118 FWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWT-ESAKQLATLFVNL 171 + +++ + L E+ E K+ T E K+L VNL Sbjct: 397 DFNVLNNKPVSLGQALEVVIQLQEKHVKDEQIEHWKKIVKTQEELKELLNKMVNL 451 >3BI4-A nrPDB Length = 516 Score = 154 bits (389), Expect = 8e-38, Method: Composition-based stats. Identities = 106/525 (20%), Positives = 172/525 (32%), Gaps = 107/525 (20%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 K V+++G GI+G+ AA LH +G+ + +VLEARDRVGGR T+ + + D+G S+ Sbjct: 8 KKKVIIIGAGIAGLKAASTLHQNGIQDCLVLEARDRVGGRLQTVTGYQGRKYDIGASWHH 67 Query: 63 PT-QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRT 121 T N + +L L + V D +NF Sbjct: 68 DTLTNPLFLEEAQLSLNDGRTRFV---------------------------FDDDNFIYI 100 Query: 122 MDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTA----ET 177 ++ GR + E EL S L + + Sbjct: 101 DEERGRVDHDKELLLEIVDNEMSK--FAELEFHQHLGVSDCSFFQLVMKYLLQRRQFLTN 158 Query: 178 HEVSAL----WFLWYVKQCGGTTRIISTTNGGQERK--FVGGSGQVSERIMDLLGDR-VK 230 ++ L +L T G + + F V +RI +K Sbjct: 159 DQIRYLPQLCRYLELWHGLDWKLLSAKDTYFGHQGRNAFALNYDSVVQRIAQSFPQNWLK 218 Query: 231 LERPVIYIDQTR-ENVLVETLNHEMYEAKYVISAIPP-----------TLGMKIHFNPPL 278 L V I + +NV V + +Y A YVI +P L +I F PPL Sbjct: 219 LSCEVKSITREPSKNVTVNCEDGTVYNADYVIITVPQSVLNLSVQPEKNLRGRIEFQPPL 278 Query: 279 PMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYT----------- 327 + ++ G++ K I ++E W + + + V Sbjct: 279 KPVIQDAFDKIHFGALGKVIFEFEECCWSNESSKIVTLANSTNEFVEIVRNAENLDELDS 338 Query: 328 -LDDTKPEGNYAAIM-----GFILAHKARKLARL----------------TKEER----L 361 L+ + + + F+ K+ +A +ER Sbjct: 339 MLEREDSQKHTSVTCWSQPLFFVNLSKSTGVASFMMLMQAPLTNHIESIREDKERLFSFF 398 Query: 362 KKLCELYAKVLGSLEALEPV---------------HYEEKNWCEEQYSGGCYTTYFPPGI 406 + + K L S + ++ + + NW + YS G Y+ FP Sbjct: 399 QPVLNKIMKCLDSEDVIDGMRPIENIANANKPVLRNIIVSNWTRDPYSRGAYSACFPGDD 458 Query: 407 LTQYGRVLRQPVD-RIYFAGTETATHWSGYMEGAVEAGERAAREI 450 + D RI FAG T +G GA E+G R A I Sbjct: 459 PVDMVVAMSNGQDSRIRFAGEHTIMDGAGCAYGAWESGRREATRI 503 >4IV9-A nrPDB Length = 557 Score = 140 bits (353), Expect = 1e-33, Method: Composition-based stats. Identities = 95/501 (18%), Positives = 170/501 (33%), Gaps = 54/501 (10%) Query: 7 VVVVGGGISGMAAAKLLHDSGLN-VVVLEARDRVGGRTYT--LRNQKVKYV-DLGGSYVG 62 V +VG GISG+ AA L +G+ VV+ E+RDR+GGR ++ + +Y+ ++G Sbjct: 41 VAIVGAGISGLVAATELLRAGVKDVVLYESRDRIGGRVWSQVFDQTRPRYIAEMGAMRFP 100 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIH---HVKGKSYPFR-GPFPPVWNPITYLDHNNF 118 P+ + K+ G+ T ++ H +GK Y + G PP Y + Sbjct: 101 PSATGLFHYLKKFGISTSTTFPDPGVVDTELHYRGKRYHWPAGKKPPELFRRVYEGWQSL 160 Query: 119 WRT--MDDMGREIPSDAPWKAPLAEEWDN--MTMKELLDKLCWTESAKQLATLFVNLCVT 174 + + G + + + + + L+ + +F Sbjct: 161 LSEGYLLEGGSLVAPLDITAMLKSGRLEEAAIAWQGWLNVFRDCSFYNAIVCIFTGRHPP 220 Query: 175 AETHEVSALWFLWY------------VKQCGGTTRIISTTNGGQERK--FVGGSGQVSER 220 F + V Q G T + NG Q + G ++ R Sbjct: 221 GGDRWARPEDFELFGSLGIGSGGFLPVFQAGFTEILRMVINGYQSDQRLIPDGISSLAAR 280 Query: 221 IMDL------LGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIH- 273 + D L DRV V I + E ++++T E VI IH Sbjct: 281 LADQSFDGKALRDRVCF-SRVGRISREAEKIIIQTEAGEQRVFDRVIVTSSNRAMQMIHC 339 Query: 274 ---FNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAY-TLD 329 L + + L K + + FW K T+ DG V Sbjct: 340 LTDSESFLSRDVARAVRETHLTGSSKLFILTRTKFWIKNKLPTTIQSDGLVRGVYCLDYQ 399 Query: 330 DTKPEGNYAAIMGFILAHKARKLARLTKE----ERLKKLCELYAKVLGSLEALEPVHYE- 384 +PEG+ ++ + A+K+ + + + L S YE Sbjct: 400 PDEPEGHGVVLLSYTWEDDAQKMLAMPDKKTRCQVLVDDLAAIHPTFASYLLPVDGDYER 459 Query: 385 ---EKNWCEEQYSGGCYTTYFPP---GILTQYGRVLRQPVD----RIYFAGTETATHWSG 434 +W + +S G + +P + + + +Y AG + G Sbjct: 460 YVLHHDWLTDPHSAGAFKLNYPGEDVYSQRLFFQPMTANSPNKDTGLYLAGCSCSFAG-G 518 Query: 435 YMEGAVEAGERAAREILHAMG 455 ++EGAV+ +A +L + G Sbjct: 519 WIEGAVQTALNSACAVLRSTG 539 >5MOG-A nrPDB Length = 497 Score = 135 bits (339), Expect = 5e-32, Method: Composition-based stats. Identities = 77/481 (16%), Positives = 158/481 (32%), Gaps = 55/481 (11%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 + VV+ G G++G++ AK L D+G ++LEARD +GG+ +++ + + G Sbjct: 15 TKPLQVVIAGAGLAGLSTAKYLADAGHKPILLEARDVLGGKIAAWKDEDGDWYETGLHIF 74 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPF-RGPFPPVWNPITYLDHNNFWR 120 I L ELG+ + +I + K F R FP N W Sbjct: 75 FGAYPNIQNLFGELGINDRLQWKEHSMIFAMPNKPGEFSRFDFP----ETLPAPLNGIWA 130 Query: 121 TMDDM-----------GREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFV 169 + + + E D T+ E + K + + + Sbjct: 131 ILRNNEMLTWPEKVKFALGLLPAMVGGQAYVEAQDGFTVSEWMKKQGVPDRVNDEVFIAM 190 Query: 170 NLCVT-AETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGS--GQVSERIMD--- 223 + + E+S L + + G + F+ G+ ++ I+D Sbjct: 191 SKALNFINPDELSMQCILIALNRFLQEKH-------GSKMAFLDGNPPERLCMPIVDHVR 243 Query: 224 LLGDRVKLERPVIYIDQTRENVLVE---TLNHEMYEAKYVISAIPPTLGMKIHFNPPLPM 280 LG V+L + I+ + V+ + + A P + + P Sbjct: 244 SLGGEVRLNSRIQKIELNPDG-TVKHFALTDGTQITGDAYVFATPVDILKLLV--PQ--E 298 Query: 281 MRN----QMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIID-----GEEAPVAYTLDDT 331 + + + ++ VI +++ D+ + + D Sbjct: 299 WKEISYFKKLEKLVGVPVINVHIWFDRKLKNTYDHLLFSRSSLLSVYADMSVTCKEYYD- 357 Query: 332 KPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEE 391 P + ++ + + E ++ + AK+ A + + + Sbjct: 358 -PNRSMLELVFAPAEEWVGR----SDTEIIEATMQELAKLFPDEIAADQSKAKILKYHVV 412 Query: 392 QYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREIL 451 + Y T + R P++ Y AG T + MEGAV +G+ A+ ++ Sbjct: 413 KTPRSVYKTIPD---CEPCRPLQRSPIEGFYLAGDYTKQKYLASMEGAVLSGKLCAQSVV 469 Query: 452 H 452 Sbjct: 470 E 470 >3WE0-A nrPDB Length = 580 Score = 120 bits (300), Expect = 2e-27, Method: Composition-based stats. Identities = 89/516 (17%), Positives = 165/516 (31%), Gaps = 80/516 (15%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT--LRNQKVKYVDLGGSYVGP 63 +V +VG GI+G+ AA L GL VV EA ++GGR + +LGG Sbjct: 67 EVAIVGAGIAGLVAAYELMKLGLKPVVYEAS-KMGGRLRSQAFNGTDGIIAELGGMRFPV 125 Query: 64 TQNRILRLAKELGLETYKVNE-----VERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNF 118 + +LGLET + ++G++Y P + + + Sbjct: 126 SSTAFYHYVDKLGLETKPFPNPLTPASRSTVIDLEGQTY---YAEKAADLPALFQEVTDA 182 Query: 119 WRTMDDMG------------REIPSDAPWKAPLAEEWDNMTMKELL-DKLCWTESAKQLA 165 W + G R++P L WD+ T + + + + + Q Sbjct: 183 WADALESGARFGDIQQAIRDRDVPRLKELWNTLVPLWDDRTFYDFVATSKAFAKLSFQHR 242 Query: 166 TLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERK-FVGGSGQVSERIMDL 224 +F + + + + TN + VGG QV + I Sbjct: 243 EVFGQVGFGTGGWDSDFPNSML-------EIFRVVMTNCDDHQHLVVGGVEQVPQGIWRH 295 Query: 225 LGDR------------VKLERP---VIYIDQTREN---VLVETLNHEMYEAKYVISAIPP 266 + +R + P V I + + V + Y A + + Sbjct: 296 VPERCAHWPEGTSLSSLHGGAPRTGVKRIARASDGRLAVTDNWGDCRHYAA-VLTTCQSW 354 Query: 267 TLGMKIHFNPPLPMMRN-QMITRVPLGSVIKCIVYYKEPFWRKK------DYCGTMIIDG 319 L +I L + + R K V PFW+ K D + D Sbjct: 355 LLTTQIDCEESLFSQKMWMALDRTRYMQSSKTFVMVDRPFWKDKDPETGRDLMSMTLTDR 414 Query: 320 EEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTK--EERLKKLCELYAKVLGSLEA 377 Y D+ + ++ A + L L E+R++ + K+ + Sbjct: 415 LTRG-TYLFDN---GDDKPGVICLSYAWMSDALKMLPHPVEKRVQLALDALKKIYPKTDI 470 Query: 378 L-----EPVHYEEKNWCEEQYSGGCYTTYFPP------GILTQYGRVLRQPVDR-IYFAG 425 +P+ +W + + G + P + + + R I+ AG Sbjct: 471 AGHIIGDPITI---SWEADPHFLGAFKGALPGHYRYNQRMYAHFMQAQMPVEQRGIFIAG 527 Query: 426 TETATHWSGYMEGAVEAGERAAREILHAMGKIPEDE 461 + + ++EGAV+ A I++ G + Sbjct: 528 DDVSWT-PAWVEGAVQTSLNAVWGIMNHFGGKTHAD 562 >3X0V-A nrPDB Length = 541 Score = 111 bits (276), Expect = 1e-24, Method: Composition-based stats. Identities = 79/495 (15%), Positives = 159/495 (32%), Gaps = 64/495 (12%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVV---VLEARDRVGGRTYT--LRNQKVKYVDLGG 58 V +VG G+SG+ A +L D + + + E+ R GGR YT + K Y D+G Sbjct: 7 PRKVCIVGAGVSGLYIAMILDDLKIPNLTYDIFESSSRTGGRLYTHHFTDAKHDYYDIGA 66 Query: 59 SYVG--PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHN 116 P+ R L K G+ K +++ G++ P + Sbjct: 67 MRYPDIPSMKRTFNLFKRTGMPLIK--------YYLDGENTPQLYNNHFFAKGVVDPYMV 118 Query: 117 NFWR-------TMDDMGREIPSDAPWKAPLAEE-----------WDNMTMKELLDKLCWT 158 + +D +G ++ + E D+MT +E L + Sbjct: 119 SVANGGTVPDDVVDSVGEKLQQAFGYYKEKLAEDFDKGFDELMLVDDMTTREYLKRGGPK 178 Query: 159 ESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVS 218 A + + T T F + + + GG+ + Sbjct: 179 GEAPKYDFFAIQWMETQNT---GTNLFDQAFSESVIDSFDFDNPTKPEWYCIEGGTSLLV 235 Query: 219 ERIMDLLGDRVKLERPVIYI----DQTRENVLVETLNHEMYEA-KYVISAIPPTLGMKIH 273 + + + L +V+ + V I D + + + + Y V + ++ Sbjct: 236 DAMKETLVHKVQNNKRVEAISIDLDAPDDGNMSVKIGGKDYSGYSTVFNTTALGCLDRMD 295 Query: 274 FN-PPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKK---DYCGTMIIDGEEAPVAYTLD 329 L + I + + K + + P+W K G D Y Sbjct: 296 LRGLNLHPTQADAIRCLHYDNSTKVALKFSYPWWIKDCGITCGGAASTDLPLRTCVYPSY 355 Query: 330 DTKPEGNYAAIMGFILAHKARKLARLTKE---------ERLKKLCELYAKVLGSLEALEP 380 + G + + + A ++ L K+ E ++ + + A++ E Sbjct: 356 NLGDTGEAVLLASYTWSQDATRIGSLVKDAPPQPPKEDELVELILQNLARLHAEHMTYEK 415 Query: 381 VH------YEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPV--DRIYFAGTETATHW 432 + Y W + GG + F PG + L +P + + G ++ H Sbjct: 416 IKEAYTGVYHAYCWANDPNVGGAF-ALFGPGQFSNLYPYLMRPAAGGKFHIVGEASSVH- 473 Query: 433 SGYMEGAVEAGERAA 447 ++ G++E+ A Sbjct: 474 HAWIIGSLESAYTAV 488 >4IVM-B nrPDB Length = 483 Score = 105 bits (261), Expect = 6e-23, Method: Composition-based stats. Identities = 82/441 (18%), Positives = 142/441 (32%), Gaps = 67/441 (15%) Query: 7 VVVVGGGISGMAAAKLLHDSGL--NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 VVV+GGGISG+AA+ L + VV++E+ +R+GG ++R +LG + P Sbjct: 11 VVVLGGGISGLAASYHLSRAPCPPKVVLVESSERLGGWIRSVRGPNGAIFELGPGGIRPA 70 Query: 65 QN---RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYL--DHNNFW 119 R L L ELGL++ + P RG P N Y+ + Sbjct: 71 GALGARTLLLVSELGLDS---------------EVLPVRGDHPAAQNRFLYVGGALHALP 115 Query: 120 RTMDDMGREIPSDA---------PWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVN 170 + + R P + P +E D T+ + E A Sbjct: 116 TGLRGLLRPSPPFSKPLFWAGLRELTKPRGKEPDE-TVHSFAQRRLGPEVASLAMDSLCR 174 Query: 171 LCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERK--------------------- 209 + E+S + Q T R I + Sbjct: 175 GVFAGNSRELSIRSCFPSLFQAEQTHRSILLGLLLGAGRTPQPDSALIRQALAERWSQWS 234 Query: 210 FVGGSGQVSERIMDLL---GDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPP 266 GG + + + L G V +PV + E +L EA +VISAIP Sbjct: 235 LRGGLEMLPQALETHLTSRGVSVLRGQPVCGLSLQAEGRWKVSLRDSSLEADHVISAIPA 294 Query: 267 TLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAY 326 ++ ++ P + ++ + SV + Y+ + + + + + Sbjct: 295 SVLSELL--PAEAAPLARALSAITAVSVAVVNLQYQGAHLPVQGFGHLVPSSEDPGVLGI 352 Query: 327 TL--------DDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKV-LGSLEA 377 D + P ++G + +E ++ + A LG E Sbjct: 353 VYDSVAFPEQDGSPPGLRVTVMLGGSWLQTLEASGCVLSQELFQQRAQEAAATQLGLKEM 412 Query: 378 LEPVHYEEKNWCEEQYSGGCY 398 C QY+ G + Sbjct: 413 PSHCLVHLHKNCIPQYTLGHW 433 >1SEZ-A nrPDB Length = 504 Score = 99.9 bits (247), Expect = 2e-21, Method: Composition-based stats. Identities = 78/516 (15%), Positives = 167/516 (32%), Gaps = 84/516 (16%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 S+ V V+G G+SG+AAA L GLNV V EA + GG+ ++ + + D G + + Sbjct: 11 SSAKRVAVIGAGVSGLAAAYKLKIHGLNVTVFEAEGKAGGKLRSVSQDGLIW-DEGANTM 69 Query: 62 GPTQNRILRLAKELGL---ETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNF 118 ++ + L LGL + + +++ +R I P + + Sbjct: 70 TESEGDVTFLIDSLGLREKQQFPLSQNKRYIARNGTPVLLPSNPIDLIKSNFLST----- 124 Query: 119 WRTMDDMGREIPSDAPWKAPLAEEWDNM--TMKELLDKLCWTESAKQLATLFVNLCVTAE 176 + + WK + + ++ + E L FV + Sbjct: 125 ----GSKLQMLLEPILWKNKKLSQVSDSHESVSGFFQRHFGKEVVDYLIDPFVAGTCGGD 180 Query: 177 THEV----SALWFLWYVKQCGGTTRI-----ISTTNGGQ---------------ERKFVG 212 + S K+ G +S N + F+G Sbjct: 181 PDSLSMHHSFPELWNLEKRFGSVILGAIRSKLSPKNEKKQGPPKTSANKKRQRGSFSFLG 240 Query: 213 GSGQVSERIMDLLGDR-VKLERPVIYI------DQTRENVLVETLNHEMYEA-----KYV 260 G +++ I L + ++L V+ + D ++ + + + ++ V Sbjct: 241 GMQTLTDAICKDLREDELRLNSRVLELSCSCTEDSAIDSWSIISASPHKRQSEEESFDAV 300 Query: 261 ISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKE--PFWRKKDYCGTMIID 318 I P + I V + I +K + + + + Sbjct: 301 IMTAPLCDVKSMKIAKRGNPFLLNFIPEVDYVPLSVVITTFKRENVKYPLEGFGVLVPSK 360 Query: 319 GEEAPV--------AYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAK 370 ++ + + D P Y F+ + R+LA+ ++ E + + + Sbjct: 361 EQQHGLKTLGTLFSSMMFPDRAPNNVY-LYTTFVGGSRNRELAKASRTELKEIVTSDLKQ 419 Query: 371 VLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVL------RQPVDRIYFA 424 +LG+ V++ ++ FP Y VL + + +++A Sbjct: 420 LLGAEGEPTYVNHLY------------WSKAFPLYG-HNYDSVLDAIDKMEKNLPGLFYA 466 Query: 425 GTETATHWSGYMEGAVEAGERAAREILHAMGKIPED 460 G + A+ +G AA ++ + + D Sbjct: 467 GNH---RGGLSVGKALSSGCNAADLVISYLESVSTD 499 >3LOV-A nrPDB Length = 475 Score = 86.8 bits (213), Expect = 2e-17, Method: Composition-based stats. Identities = 78/456 (17%), Positives = 156/456 (34%), Gaps = 52/456 (11%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDS--GLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 + +V+VGGGI+G+AAA + LN+ +LEA +R+GG+ T R ++ G Sbjct: 3 SSKRLVIVGGGITGLAAAYYAERAFPDLNITLLEAGERLGGKVATYREDGFT-IERGPDS 61 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPF-RGPFPPVWN------PITYL 113 ++ + L + +GL E+L+ + +++ G P+ P Sbjct: 62 YVARKHILTDLIEAIGL-------GEKLVRNNTSQAFILDTGGLHPIPKGAVMGIPTDLD 114 Query: 114 DHNNFWRTMDDMGREIP-----SDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLF 168 ++ +E+ + P + ++ L + + L + Sbjct: 115 LFRQTTLLTEEEKQEVADLLLHPSDSLRIPEQDIPLGEYLRPRLGDALVEKLIEPLLSGI 174 Query: 169 VNLCVTAETHEVSALWFLWYVKQCGGTTRII---------------STTNGGQERKFVGG 213 + + + F+ ++ G + + GQ G Sbjct: 175 YAGNIDQMSTFATYPQFVANEQKAGSLFEGMRLMRPLDQLPQTPQTTIKATGQFLSLETG 234 Query: 214 SGQVSERIMDLL-GDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKI 272 + ER+ ++L ++LE P++ I + ++T + Y A YV+ IP +++ Sbjct: 235 LESLIERLEEVLERSEIRLETPLLAISREDGRYRLKTDHGPEY-ADYVLLTIPHPQVVQL 293 Query: 273 HFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTK 332 + LP + +T +V + + + + A T D K Sbjct: 294 LPDAHLPELEQ--LTTHSTATVTMIFDQQQSLPIEGTGFV--VNRRAPYSITACTAIDQK 349 Query: 333 PEG---NYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWC 389 ++ + F+ L + E + + + K+ G LEP Sbjct: 350 WNHSAPDHTVLRAFVGRPGNDHLVHESDEVLQQAVLQDLEKICG--RTLEPKQVIISR-L 406 Query: 390 EEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAG 425 + YT I VL Q IY AG Sbjct: 407 MDGLP--AYTVGHADRIQRVREEVLAQ-YPGIYLAG 439 >3I6D-A nrPDB Length = 470 Score = 84.9 bits (208), Expect = 7e-17, Method: Composition-based stats. Identities = 81/475 (17%), Positives = 157/475 (33%), Gaps = 58/475 (12%) Query: 1 MSN-KCDVVVVGGGISGMAAAKLL------HDSGLNVVVLEARDRVGGRTYTLRNQKVKY 53 MS+ K VV++GGGI+G+AAA + + L + ++EA RVGG+ T++ Sbjct: 1 MSDGKKHVVIIGGGITGLAAAFYMEKEIKEKNLPLELTLVEASPRVGGKIQTVKKDGY-I 59 Query: 54 VDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYL 113 ++ G + +L K+LGLE VN + + ++ + P Sbjct: 60 IERGPDSFLERKKSAPQLVKDLGLEHLLVNNATGQSYVLVNRTLHPMPKGAVMGIPTKIA 119 Query: 114 DHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCV 173 + + + + + + P ++ D+ ++ E + E + L ++ Sbjct: 120 PFVSTG--LFSLSGKARAAMDFILPASKTKDDQSLGEFFRRRVGDEVVENLIEPLLSGIY 177 Query: 174 TAETHEVS----ALWFLWYVKQC------------GGTTRIISTTNGGQERKFVGGSGQV 217 + ++S F ++ G+ + ++ GQ + G + Sbjct: 178 AGDIDKLSLMSTFPQFYQTEQKHRSLILGMKKTRPQGSGQQLTAKKQGQFQTLSTGLQTL 237 Query: 218 SERIMDLLGD-RVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNP 276 E I L +V V + + +E N +A VI P + Sbjct: 238 VEEIEKQLKLTKVYKGTKVTKLSHSGSCYSLELDNGVTLDADSVIVTAPHKAAAGMLSEL 297 Query: 277 PLPMMRNQMITRVPLGSVIKCIVYYKE--PFWRKKDYCGTMIIDGEEAPVAYTLDDTKPE 334 P + + SV + + E + + + + A A T + K Sbjct: 298 P----AISHLKNMHSTSVANVALGFPEGSVQMEHEGTGFVISRNSDFAITACTWTNKKWP 353 Query: 335 GNYAAIMGFILAH----KARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCE 390 + A+ + L+ + + + E KV+ E W E Sbjct: 354 HAAPEGKTLLRAYVGKAGDESIVDLSDNDIINIVLEDLKKVMNINGEPEMT--CVTRWHE 411 Query: 391 EQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSG-YMEGAVEAGE 444 + QY +Q RI A+ + G YM GA G Sbjct: 412 ---------------SMPQYHVGHKQ---RIKELREALASAYPGVYMTGASFEGV 448 >4DGK-A nrPDB Length = 501 Score = 80.2 bits (196), Expect = 2e-15, Method: Composition-based stats. Identities = 59/315 (18%), Positives = 109/315 (34%), Gaps = 42/315 (13%) Query: 9 VVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQNRI 68 V+G G G+A A L +G+ V++LE RD+ GGR Y +Q + D G + + + I Sbjct: 6 VIGAGFGGLALAIRLQAAGIPVLLLEQRDKPGGRAYVYEDQGFTF-DAGPTVIT-DPSAI 63 Query: 69 LRLAKELG------LETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNF--WR 120 L G +E V RL GK + + + I + + +R Sbjct: 64 EELFALAGKQLKEYVELLPVTPFYRLCWE-SGKVFNYDNDQTRLEAQIQQFNPRDVEGYR 122 Query: 121 TMDDMGREIPSDAPWK---APLAEEWDNMTMKELLDKLC------------WTESAKQLA 165 D R + + K P D + L KL + + A Sbjct: 123 QFLDYSRAVFKEGYLKLGTVPFLSFRDMLRAAPQLAKLQAWRSVYSKVASYIEDEHLRQA 182 Query: 166 TLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSE---RIM 222 F +L V S+++ L + + GG+G + + ++ Sbjct: 183 FSFHSLLVGGNPFATSSIYTLIHALEREWGVWFP-----------RGGTGALVQGMIKLF 231 Query: 223 DLLGDRVKLERPVIYIDQTRENV-LVETLNHEMYEAKYVIS-AIPPTLGMKIHFNPPLPM 280 LG V L V +++ T + V + + + V S A + P + Sbjct: 232 QDLGGEVVLNARVSHMETTGNKIEAVHLEDGRRFLTQAVASNADVVHTYRDLLSQHPAAV 291 Query: 281 MRNQMITRVPLGSVI 295 ++ + + + + Sbjct: 292 KQSNKLQTKRMSNSL 306 >2IVE-A nrPDB Length = 478 Score = 69.8 bits (169), Expect = 3e-12, Method: Composition-based stats. Identities = 73/410 (17%), Positives = 127/410 (30%), Gaps = 39/410 (9%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 +V VVGGGISG+A A L G + V+LE+ R+GG T V+ G + + Sbjct: 18 NVAVVGGGISGLAVAHHLRSRGTDAVLLESSARLGGAVGTHALAGY-LVEQGPNSFLDRE 76 Query: 66 NRILRLAKELGLET---YKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTM 122 LA L LE +R + +G+ PP + L R Sbjct: 77 PATRALAAALNLEGRIRAADPAAKRRYVYTRGRLRSVPAS-PPAFLASDILPLGARLRVA 135 Query: 123 DDM-GREIP--SDAPWKAPLAEEWDNMTMKELLDKLCWTESA-----KQLATLFVNLCVT 174 ++ R P D A + + LLD + A +A F L Sbjct: 136 GELFSRRAPEGVDESLAAFGRRHLGHRATQVLLDAVQTGIYAGDVEQLSVAATFPMLVKM 195 Query: 175 AETHE---VSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKL 231 H + A+ +Q + G F GG + + + LGD + Sbjct: 196 EREHRSLILGAIRAQKAQRQAALPA-GTAPKLSGALSTFDGGLQVLIDALAASLGDAAHV 254 Query: 232 ERPVIYIDQTRENVLVETLNH---EMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITR 288 V + + + H V+ A P K+ PL ++ Sbjct: 255 GARVEGLAREDGGWRLIIEEHGRRAELSVAQVVLAAPAHATAKLL--RPLDDALAALVAG 312 Query: 289 VPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPV--------AYTLDDTKPEGNYAAI 340 + + + + D G ++ E+ + + Y+ + Sbjct: 313 IAYAPIAVVHLGFDAGTLPAPDGFGFLVPAEEQRRMLGAIHASTTFPFRAEGGRVLYSCM 372 Query: 341 MGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEK--NW 388 +G A + + + L L + L +L + + W Sbjct: 373 VGG--ARQPGLVE-----QDEDALAALAREELKALAGVTARPSFTRVFRW 415 >5ZBC-A nrPDB Length = 451 Score = 69.5 bits (168), Expect = 3e-12, Method: Composition-based stats. Identities = 75/473 (15%), Positives = 149/473 (31%), Gaps = 70/473 (14%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDS----GLNVVVLEARDRVGGRTYTLRNQKVKYVDL 56 M + D+ +VG GISG+ A L DS GL++ + + + GGR + ++L Sbjct: 21 MKHSSDICIVGAGISGLTCASHLLDSPACRGLSLRIFDMQQEAGGRIRSKMLDGKASIEL 80 Query: 57 GGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRG-PFPPVWNPITYLDH 115 G P + + + + K + YPF F Sbjct: 81 GAGRYSP--------------QLHPHFQSAMQHYSQKSEVYPFTQLKFKSHVQQKLKRAM 126 Query: 116 NNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTA 175 N + + G+E + + M D L + + ++A V Sbjct: 127 NELSPRLKEHGKESFLQFVSRYQGHDSAVGMIRSMGYDALFLPDISAEMAYDIVG--KHP 184 Query: 176 ETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPV 235 E V+ + G G Q + + G R L + Sbjct: 185 EIQSVTDNDANQWFAAETGFA----------------GLIQGIKAKVKAAGARFSLGYRL 228 Query: 236 IYIDQTRENVLVETLN----HEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPL 291 + + + L++ + +++I AIPP+ ++ + P + + Sbjct: 229 LSVRTDGDGYLLQLAGDDGWKLEHRTRHLILAIPPSAMAGLNVDFP------EAWSGARY 282 Query: 292 GS--VIKCIVYYKEPFWRKKDYCGTM-IIDGEEAPVAYTLDDT---KPEGNYAAIMGFIL 345 GS + K + Y EP+W + I+D + + D + A + Sbjct: 283 GSLPLFKGFLTYGEPWWLDYKLDDQVLIVDNPLRKIYFKGDKYLFFYTDSEMANYWRGCV 342 Query: 346 AHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWCEE-QYSGGCYTTYFPP 404 A L + + +P+ + K W ++ + P Sbjct: 343 AEGEDGYLEQI-RTHLASALGIVRE-----RIPQPLAHVHKYWAHGVEFCRD--SDIDHP 394 Query: 405 GILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKI 457 L+ + A ++ T +G+MEG + + A+R +L + Sbjct: 395 SALSHRDSGI--------IACSDAYTEHAGWMEGGLLSAREASRLLLQRIAAK 439 >3UKH-A nrPDB Length = 519 Score = 68.7 bits (166), Expect = 7e-12, Method: Composition-based stats. Identities = 78/493 (15%), Positives = 150/493 (30%), Gaps = 68/493 (13%) Query: 4 KCDVVVVGGGISGMAAAKLL-HDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 DV+V+G G +G+ AAK L G + +++++ + GG T + D+GG + Sbjct: 6 SVDVLVIGAGPTGLGAAKRLNQIDGPSWMIVDSNETPGGLASTDVTPEGFLYDVGGHVIF 65 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTM 122 E L + I +V+ + PF N I+ L + + Sbjct: 66 SHYKYFDDCLDE-ALPKEDDWYTHQRISYVRCQGQWVPYPFQ---NNISMLPKEEQVKCI 121 Query: 123 DDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSA 182 D M DA +A +A T E + ++ T A + T ++ Sbjct: 122 DGM-----IDAALEARVANTKPK-TFDEWIVRMMGTGIADLFMRPYNFKVWAVPTTKMQC 175 Query: 183 LWFLWYVKQCG----------GTTRIISTTNGGQERKFVGGSGQVSERIMDLLG-DRVKL 231 W V G T N GG+G + + + L ++ + Sbjct: 176 AWLGERVAAPNLKAVTTNVILGKTAGNWGPNATFRFPARGGTGGIWIAVANTLPKEKTRF 235 Query: 232 ERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRV-- 289 N V + K ++S + + + L + Q+ Sbjct: 236 GEKGKVTKVNANNKTVTLQDGTTIGYKKLVSTMAVDFLAEAMNDQELVGLTKQLFYSSTH 295 Query: 290 ----------PLGSVIKCIVYYKE---PFWRKKDYCGTMIIDGEEA----PVAYTLDDTK 332 P KC +Y+ E PF+R + + EA P D ++ Sbjct: 296 VIGVGVRGSRPERIGDKCWLYFPEDNCPFYRATIFSNYSPYNQPEASKKLPTMQLADGSR 355 Query: 333 PE---GNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNW- 388 P+ +L + + +E L + E V + + Sbjct: 356 PQSTEAKEGPYWSIMLEVSESSMKPVNQETILADCIQGLVNTEMLKPTDEIVSTYHRRFD 415 Query: 389 ----------------------CEEQYSGGCYTTYFPPGILTQYGRVLR-QPVDRIYFAG 425 ++ +S G + ++ + +L + VD I Sbjct: 416 HGYPTPTLEREGALTQILPKLQDKDIWSRGRFGSWRYEVGNQDHSFMLGVEAVDNIVNGA 475 Query: 426 TETATHWSGYMEG 438 E ++ ++ G Sbjct: 476 VELTLNYPDFVNG 488 >1I8T-A nrPDB Length = 367 Score = 56.0 bits (133), Expect = 4e-08, Method: Composition-based stats. Identities = 48/271 (17%), Positives = 85/271 (31%), Gaps = 34/271 (12%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D ++VG G+ G A L V+V+E R+ +GG YT + ++ G Sbjct: 3 DYIIVGSGLFGAVCANELKKLNKKVLVIEKRNHIGGNAYTEDCEGIQIHKYGAHIFHTND 62 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 I +L +E + I+ K K + P + W D Sbjct: 63 KYIWDYVNDL-VEFNRFTNSPLAIY--KDKLFNL---------PFNMNTFHQMWGVKDPQ 110 Query: 126 GREIPSDAPWKAPLAEEWDNM--TMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSAL 183 + A + D + ++E L + + L + E+ A Sbjct: 111 EAQN----IINAQKKKYGDKVPENLEEQAISLVGEDLYQALIKGYTEKQWGRSAKELPAF 166 Query: 184 WFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRE 243 + S G VGG ++ E++++ G VKL ID ++ Sbjct: 167 IIKRIPVRFTFDNNYFSDRYQGIP---VGGYTKLIEKMLE--GVDVKLG-----IDFLKD 216 Query: 244 NVLVETLNHEMYEAKYVISAIPPTLGMKIHF 274 + +A +I P F Sbjct: 217 ------KDSLASKAHRIIYTGPIDQYFDYRF 241 >4C5O-A nrPDB Length = 357 Score = 55.2 bits (131), Expect = 7e-08, Method: Composition-based stats. Identities = 19/39 (48%), Positives = 26/39 (66%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 + DVVV+GGG SG++A L SGL+ V+L+A GG Sbjct: 2 DSVDVVVIGGGQSGLSAGYFLRRSGLSYVILDAEASPGG 40 >4ZCC-A nrPDB Length = 336 Score = 54.1 bits (128), Expect = 2e-07, Method: Composition-based stats. Identities = 23/101 (22%), Positives = 44/101 (43%), Gaps = 2/101 (1%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 + ++G GI+G++AA+ L +G V + + GGR + R+ +D+G Y Sbjct: 5 IAIIGTGIAGLSAAQALTSAGHQVHLFDKSRGSGGRMSSKRSDAGS-LDMGAQYFTARDR 63 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVW 107 R K+ + + V+E L+++ G W Sbjct: 64 RFATAVKQWQAQGH-VSEWTPLLYNFHGGRLSPSPDEQVRW 103 Score = 28.2 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 38/240 (15%), Positives = 80/240 (33%), Gaps = 28/240 (11%) Query: 213 GSGQVSERIMDLLGDRVKLERPVIYI---DQTRENVLVETLNHEMYEAKYVISAIPPTLG 269 G ++ + L V + + +Q + E+ NH + +VI A P Sbjct: 108 GMSAITRAMRGDLP--VSFSCRITDVFRGEQHWNLLDAESENHGPFS--HVIIATPAPQA 163 Query: 270 MKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLD 329 + ++ V + + ++ P G + D +A Sbjct: 164 TALL---AAAPKLASVVAGVKMDPTWAVALAFETPLQTP--MQGCFVQDSPLDWLARNRS 218 Query: 330 DTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLGSLEALEPVHYEEKNWC 389 + + + + +R+ ++E+ ++ L +A+++ PV W Sbjct: 219 KPGRDDTLDSWVLHATSQWSRQNLDASREQVIEHLHGAFAELI-DCAMPAPVFSLAHRWL 277 Query: 390 EEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGERAARE 449 Y P ++G + + IY G + SG +EGA +G+ AAR Sbjct: 278 -----------YARPAGSHEWGALSDADLG-IYVCG-DWCL--SGRVEGAWLSGQEAARR 322 >5NMX-A nrPDB Length = 425 Score = 53.7 bits (127), Expect = 2e-07, Method: Composition-based stats. Identities = 32/129 (24%), Positives = 49/129 (37%), Gaps = 7/129 (5%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 V V+G G SG+ AA+ L +G V+V E VGG T+ ++ D Y QN Sbjct: 4 VAVLGAGPSGLTAARYLKQAGFEVMVFERYHHVGG-TWNYTDETWMSEDGRPVYSSMYQN 62 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMG 126 + L KEL + H ++G P + N D + + Sbjct: 63 LFVNLPKEL--MAFPDFPF----HDIEGSYVPSKEVLKYFDNFTDAFDLRKLIKLQHHVE 116 Query: 127 REIPSDAPW 135 P ++ W Sbjct: 117 NVRPCESGW 125 >3KYB-A nrPDB Length = 390 Score = 53.3 bits (126), Expect = 2e-07, Method: Composition-based stats. Identities = 21/105 (20%), Positives = 40/105 (38%), Gaps = 5/105 (4%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK-YVDL-GGSYV 61 +++VG G SG + L + G V +++ RD +GG +Y R+ + V + G Sbjct: 3 SKKILIVGAGFSGAVIGRQLAEKGHQVHIIDQRDHIGGNSYDARDSETNVMVHVYGPHIF 62 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPV 106 + + VN R+ V G+ + + Sbjct: 63 HTDNETVWNYINKHAEMMPYVN---RVKATVNGQVFSLPINLHTI 104 >5BR7-A nrPDB Length = 393 Score = 52.5 bits (124), Expect = 4e-07, Method: Composition-based stats. Identities = 38/232 (16%), Positives = 71/232 (30%), Gaps = 21/232 (9%) Query: 6 DVVVVGGGISGMAAA-KLLHDSGLNVVVLEARDRVGGRTYTLRNQ--KVKYVDLGGSYVG 62 D++VVG G+ G+ A + G V+++E R +GG Y+ ++ G Sbjct: 5 DLIVVGSGLFGLTVAERAASQLGKKVLIVEKRSHLGGNAYSEAEPETGIEIHKYGAHLFH 64 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT-YLDHNNFWRT 121 + R+ + T R+ G +Y F + Y + Sbjct: 65 TSNKRVWDYVNQF---TAFTGYQHRVFAMHNGTAYQFPMGLGLINQFFGRYYTPDEAREL 121 Query: 122 MDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVS 181 + + EI + D ++E L + + + E+ Sbjct: 122 IKEQSAEI-----------DSKDATNLEEKAISLIGRPLYEAFIRDYTAKQWQTDPKELP 170 Query: 182 ALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLER 233 A + R + T G V G Q + D V+L+ Sbjct: 171 AGNITRLPVRYNFDNRYFNDTYEGLP---VDGYAQWLSNMADHENIEVRLDT 219 >3KKJ-A nrPDB Length = 336 Score = 52.1 bits (123), Expect = 6e-07, Method: Composition-based stats. Identities = 22/101 (21%), Positives = 42/101 (41%), Gaps = 2/101 (1%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 + ++G GI+G++AA+ L +G V + + GGR + R+ +D+G Y Sbjct: 5 IAIIGTGIAGLSAAQALTAAGHQVHLFDKSRGSGGRMSSKRSDAGA-LDMGAQYFTARDR 63 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVW 107 R K+ + + V E L+++ W Sbjct: 64 RFATAVKQWQAQGH-VAEWTPLLYNFHAGRLSPSPDEQVRW 103 Score = 31.3 bits (69), Expect = 0.96, Method: Composition-based stats. Identities = 41/257 (15%), Positives = 87/257 (33%), Gaps = 30/257 (11%) Query: 197 RIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLV---ETLNHE 253 R+ + + G ++ + + V + + + E+ + E NH Sbjct: 92 RLSPSPDEQVRWVGKPGMSAITRAMRGDMP--VSFSCRITEVFRGEEHWNLLDAEGQNHG 149 Query: 254 MYEAKYVISAIP-PTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYC 312 + +VI A P P + P L ++ V + + ++ P Sbjct: 150 PFS--HVIIATPAPQASTLLAAAPKL----ASVVAGVKMDPTWAVALAFETPLQTP--MQ 201 Query: 313 GTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVL 372 G + D +A + + + + +R+ ++E+ ++ L +A+++ Sbjct: 202 GCFVQDSPLDWLARNRSKPERDDTLDTWILHATSQWSRQNLDASREQVIEHLHGAFAELI 261 Query: 373 GSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHW 432 PV W Y P ++G + + IY G + Sbjct: 262 -DCTMPAPVFSLAHRWL-----------YARPAGAHEWGALSDADLG-IYVCG-DWCL-- 305 Query: 433 SGYMEGAVEAGERAARE 449 SG +EGA +G+ AAR Sbjct: 306 SGRVEGAWLSGQEAARR 322 >4MO2-B nrPDB Length = 368 Score = 51.0 bits (120), Expect = 1e-06, Method: Composition-based stats. Identities = 22/126 (17%), Positives = 41/126 (32%), Gaps = 3/126 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D ++VG G+ G A + G +V+E R+ +GG YT + + G + Sbjct: 3 DYLIVGSGLFGSIFAYEATEKGYTCLVVEQREHIGGNCYTENIKNINVHKYGAHIFRTSD 62 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 I + + +N I K + Y N + ++ Sbjct: 63 QNIWDYMNQFCEFNHFIN---SPIAIYKDEIYNLPFNMNTFSKLWGIKTPNEARKIIEMQ 119 Query: 126 GREIPS 131 + I Sbjct: 120 KQIIQH 125 >3BHF-A nrPDB Length = 390 Score = 50.6 bits (119), Expect = 1e-06, Method: Composition-based stats. Identities = 47/286 (16%), Positives = 90/286 (31%), Gaps = 65/286 (22%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 MS DV+VVG G GMAA L G+ ++++A D +T + Sbjct: 1 MSTHFDVIVVGAGSMGMAAGYQLAKQGVKTLLVDAFDPP----HTNGSHHGD-------- 48 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 +I+R + E + P +W + H+ + Sbjct: 49 -----TKIIR---------HAYGEGREYV--------PLALRSQELWYELEKETHHKIFT 86 Query: 121 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV 180 + + A +AE + L L + + + + V Sbjct: 87 KTGVL---VFGPKGESAFVAETMEAAKEHSLTVDLLEGDEINKR---WPGITVPEN---- 136 Query: 181 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ 240 Y + ++ + N + + + + G +V V D Sbjct: 137 -------YNAIFEPNSGVLFSENCIRAYR----------ELAEARGAKVLTHTRVEDFDI 179 Query: 241 TRENVLVETLNHEMYEAKYVISAI---PPTLGMKIHFNPPLPMMRN 283 + ++V +ET N Y A +I ++ L K++ + PL R Sbjct: 180 SPDSVKIETANG-SYTADKLIVSMGAWNSKLLSKLNLDIPLQPYRQ 224 >2YQU-A nrPDB Length = 455 Score = 50.2 bits (118), Expect = 2e-06, Method: Composition-based stats. Identities = 47/272 (17%), Positives = 93/272 (34%), Gaps = 27/272 (9%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGR-TYTLRNQKVKYVDLGGSYVGPT 64 D++V+G G G AA G+ V V+E +GG ++ Sbjct: 3 DLLVIGAGPGGYVAAIRAAQLGMKVGVVEKEKALGGTCLRVGCIPSKALLETTERIYEAK 62 Query: 65 QNRILRLAK--ELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTM 122 + + K EL L ++ + + + +G + F+ + Sbjct: 63 KGLLGAKVKGVELDLPALMAHKDKVVQANTQGVEFLFKKNGIARHQGTARFLSERKV-LV 121 Query: 123 DDMGREIPSDAPW----KAPLAEEWDNMTMKELL---DKLCWTESAKQLATL---FVNLC 172 ++ G E+ + APL W + + ++ + L + E K+L + + L Sbjct: 122 EETGEELEARYILIATGSAPLIPPWAQVDYERVVTSTEALSFPEVPKRLIVVGGGVIGLE 181 Query: 173 VTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLE 232 + H + A + RI+ T + R +ER+ G ++ Sbjct: 182 LGVVWHRLGAEVIVL-----EYMDRILPTMDLEVSRA--------AERVFKKQGLTIRTG 228 Query: 233 RPVIYIDQTRENVLVETLNHEMYEAKYVISAI 264 V + + VE E+ EA V+ A+ Sbjct: 229 VRVTAVVPEAKGARVELEGGEVLEADRVLVAV 260 Score = 35.6 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 ++VVGGG+ G+ + H G V+VLE DR+ Sbjct: 167 PKRLIVVGGGVIGLELGVVWHRLGAEVIVLEYMDRI 202 >3MJ4-A nrPDB Length = 397 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 4/96 (4%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT-LRNQKVKYVDLGGSYVGPT 64 D ++VG G +G A+ L SG V++++ R +GG Y + V G Sbjct: 31 DYLIVGAGFAGSVLAERLASSGQRVLIVDRRPHIGGNAYDCYDDAGVLIHPYGPHIFHTN 90 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFR 100 + E R++ V G+ P Sbjct: 91 SKDVFEYLSRF-TEWRPYQH--RVLASVDGQLLPIP 123 >4RPJ-A nrPDB Length = 399 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 39/237 (16%), Positives = 72/237 (30%), Gaps = 21/237 (8%) Query: 1 MSNKCDVVVVGGGISGMA-AAKLLHDSGLNVVVLEARDRVGGRTYTLR--NQKVKYVDLG 57 M+ + D+ VVG G G+ A ++ V+VLE R +GG Y+ ++ G Sbjct: 4 MTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVHKYG 63 Query: 58 GSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT-YLDHN 116 + R+ ++ T + R+ G++Y F V Y Sbjct: 64 AHLFHTSNKRVWDYVRQF---TDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPE 120 Query: 117 NFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAE 176 + + + EI + D ++E L + + + Sbjct: 121 QARQLIAEQAAEI-----------DTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTD 169 Query: 177 THEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLER 233 E+ A + R S T G G + + V+L Sbjct: 170 PKELPAANITRLPVRYTFDNRYFSDTYEGLP---TDGYTAWLQNMAADHRIEVRLNT 223 >2CVJ-A nrPDB Length = 180 Score = 49.8 bits (117), Expect = 3e-06, Method: Composition-based stats. Identities = 23/71 (32%), Positives = 35/71 (49%), Gaps = 1/71 (1%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE-ARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 DV+VVGGG SG++AA L +GL V+VL+ R +V G + + G + Sbjct: 3 DVIVVGGGPSGLSAALFLARAGLKVLVLDGGRSKVKGVSRVPNYPGLLDEPSGEELLRRL 62 Query: 65 QNRILRLAKEL 75 + R E+ Sbjct: 63 EAHARRYGAEV 73 >5VJ7-A nrPDB Length = 476 Score = 48.7 bits (114), Expect = 7e-06, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 N V ++G G +G+ A L G V + EA + GG Sbjct: 153 NGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG 191 >5JFC-L nrPDB Length = 474 Score = 48.3 bits (113), Expect = 7e-06, Method: Composition-based stats. Identities = 13/39 (33%), Positives = 19/39 (48%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 N V ++G G +G+ A L G V + EA + GG Sbjct: 153 NGKKVAIIGAGPAGLTCAADLAKMGYEVTIYEALHQPGG 191 >2Q7V-A nrPDB Length = 325 Score = 48.3 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 24/96 (25%), Positives = 49/96 (51%), Gaps = 4/96 (4%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT-YTLRNQKVKYVDLGGSYVGPT 64 DVV++GGG +G+ AA + L+ ++LE + GG+ ++ + + + Sbjct: 10 DVVIIGGGPAGLTAAIYTGRAQLSTLILE-KGMPGGQIAWSEEVENFPGFPEPIAGMELA 68 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFR 100 Q R+ + A++ G + +++EV+ + H YPF Sbjct: 69 Q-RMHQQAEKFGAKV-EMDEVQGVQHDATSHPYPFT 102 >4OVI-A nrPDB Length = 542 Score = 48.3 bits (113), Expect = 8e-06, Method: Composition-based stats. Identities = 30/131 (22%), Positives = 49/131 (37%), Gaps = 8/131 (6%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 + DV+VVG G SG+ A L + G +V V+E VGG + D+ + Sbjct: 15 EEVDVLVVGAGFSGLYALYRLRELGRSVHVIETAGDVGG-VWYWNRYPGARCDI--ESIE 71 Query: 63 PTQNRILRLAKELGLETYKVNEVE--RLIHHVKGKSYPFRG--PFPPVWNPITYLDHNNF 118 + + +E ++ E R I+ V K + R F + + N Sbjct: 72 YCYSFSEEVLQEWNWTERYASQPEILRYINFVADK-FDLRSGITFHTTVTAAAFDEATNT 130 Query: 119 WRTMDDMGREI 129 W + G I Sbjct: 131 WTVDTNHGDRI 141 >4YRY-B nrPDB Length = 468 Score = 47.5 bits (111), Expect = 1e-05, Method: Composition-based stats. Identities = 17/40 (42%), Positives = 22/40 (55%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 S K V VVG G +G+ AA L G +V + EA + GG Sbjct: 138 SKKEKVAVVGSGPAGLTAAADLAKMGYHVDIFEAFHKPGG 177 >3URH-A nrPDB Length = 491 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 43/280 (15%), Positives = 82/280 (29%), Gaps = 31/280 (11%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D++V+G G G A G+ V V+E R GG + K + Q Sbjct: 27 DLIVIGSGPGGYVCAIKAAQLGMKVAVVEKRSTYGGTCLNVGCIPSKALLHASEMFHQAQ 86 Query: 66 NRILRLAKE-----LGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 + + L E L L+ ++ + +V G S+ F+ + + Sbjct: 87 HGLEALGVEVANPKLNLQKMMAHKDATVKSNVDGVSFLFKKNKIDGFQGTGKVLGQGKVS 146 Query: 121 TMDDMGREIPSDAPWKAPLAEEWD-------NMTMKELLDKLCWTESAKQLATLFVNLCV 173 ++ G E +A D + E A + + + Sbjct: 147 VTNEKGEE-QVLEAKNVVIATGSDVAGIPGVEVAFDEKTIVSSTGALALEKVPASMIVVG 205 Query: 174 TAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSG----QVSERIMDLLGDRV 229 V L + G ++ + GG + +R++ G Sbjct: 206 GG----VIGLELGSVWARLGAKVTVVEFLDTIL-----GGMDGEVAKQLQRMLTKQGIDF 256 Query: 230 KLERPVIYIDQTRENVLVETL-----NHEMYEAKYVISAI 264 KL V ++ + V +A+ V+ A Sbjct: 257 KLGAKVTGAVKSGDGAKVTFEPVKGGEATTLDAEVVLIAT 296 Score = 31.7 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 12/38 (31%), Positives = 19/38 (50%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 ++VVGGG+ G+ + G V V+E D + G Sbjct: 198 PASMIVVGGGVIGLELGSVWARLGAKVTVVEFLDTILG 235 >3K30-A nrPDB Length = 690 Score = 47.1 bits (110), Expect = 2e-05, Method: Composition-based stats. Identities = 18/37 (48%), Positives = 24/37 (64%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT 43 V+VVG G SG+ AA+ L G +VV+ EA +GGR Sbjct: 394 VLVVGAGPSGLEAARALGVRGYDVVLAEAGRDLGGRV 430 >4Y4M-A nrPDB Length = 290 Score = 46.4 bits (108), Expect = 3e-05, Method: Composition-based stats. Identities = 16/29 (55%), Positives = 19/29 (65%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DVV+VG G SG+ A+ L G VVVLE Sbjct: 61 DVVIVGAGPSGLTCARYLAKEGFKVVVLE 89 >4Y4N-A nrPDB Length = 286 Score = 46.0 bits (107), Expect = 4e-05, Method: Composition-based stats. Identities = 16/30 (53%), Positives = 20/30 (66%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DV +VGGG SG+ AA+ + G VVVLE Sbjct: 53 VDVAIVGGGPSGLTAARYIAKEGYKVVVLE 82 >5Z70-A nrPDB Length = 605 Score = 45.6 bits (106), Expect = 5e-05, Method: Composition-based stats. Identities = 39/253 (15%), Positives = 81/253 (32%), Gaps = 23/253 (9%) Query: 9 VVGGGISGMAAAKLLHDSGL----NVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 ++G GI+G+A+A L G ++ +L+A GG N + Y+ GG + Sbjct: 9 IIGSGIAGLASAFYLIRDGRMKGQDITILDAVGTPGGSLDGSGNAEDGYLIRGGREMNWN 68 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDD 124 + L +++ E + Y P W+ + R Sbjct: 69 YDHFWDLFQDI-----PALEYPSPYSVLDE--YRAVNDNDPNWSKSRLMHKQGQIRDFST 121 Query: 125 MGREIPSDAPWKAPL---AEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVS 181 +G L E+ D++T+++ + L+ ++ S Sbjct: 122 LGLSSAHQWELIKLLLKRKEDLDDITIEQY---FSDSFLETNFWYLWRSMFAFQNWQ--S 176 Query: 182 ALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLL---GDRVKLERPVIYI 238 L Y+ + ++ + K+ +++ L G V+ V + Sbjct: 177 LLEVKLYMHRFLDAIDGLTDMSALVFPKY-NQYDSFVVPLVNYLKGQGVNVEFGTRVYDL 235 Query: 239 DQTRENVLVETLN 251 D T N + Sbjct: 236 DMTDNNGERTVTS 248 >3LXD-A nrPDB Length = 415 Score = 45.6 bits (106), Expect = 6e-05, Method: Composition-based stats. Identities = 18/43 (41%), Positives = 25/43 (58%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY 44 + + VV+GGG G+ AA +L G+NV +LEA RV R Sbjct: 150 AGAKNAVVIGGGYIGLEAAAVLTKFGVNVTLLEALPRVLARVA 192 >3ATQ-A nrPDB Length = 453 Score = 45.2 bits (105), Expect = 6e-05, Method: Composition-based stats. Identities = 37/185 (20%), Positives = 71/185 (38%), Gaps = 24/185 (12%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--DRVGGRTYTLRNQKVKYVDLGGSYV 61 K DV+++GGG +G +AA L GL +++++++ +R+G + K + LG Y Sbjct: 6 KYDVLIIGGGFAGSSAAYQLSRRGLKILLVDSKPWNRIGDKPCGDAVSKAHFDKLGMPYP 65 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRT 121 + K G++ Y + + + V G+ + P L + + Sbjct: 66 KGEE----LENKINGIKLY--SPDMQTVWTVNGEGFELNAP----------LYNQRVLKE 109 Query: 122 MDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVS 181 D G EI P+ E D + + + T++ + V A + S Sbjct: 110 AQDRGVEIWDLTTAMKPIFE--DGYVK----GAVLFNRRTNEELTVYSKVVVEATGYSRS 163 Query: 182 ALWFL 186 L Sbjct: 164 FRSKL 168 >1ZOV-A nrPDB Length = 386 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 49/286 (17%), Positives = 88/286 (30%), Gaps = 67/286 (23%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 S DV+VVG G GMAA L G+ +++++ D +T + Sbjct: 1 STHFDVIVVGAGSMGMAAGYYLAKQGVKTLLVDSFDPP----HTNGSHHGD--------- 47 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITY-LDHNNFWR 120 RI+R + E + PF + Y L+ + Sbjct: 48 ----TRIIR---------HAYGEGREYV------------PFALRAQELWYELEKETHHK 82 Query: 121 TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV 180 G + A ++E + + L +L KQL + + V Sbjct: 83 IFTQTGVLVYGPKGGSAFVSETMEAANIHSLEHELFEG---KQLTDRWAGVEVPDN---- 135 Query: 181 SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ 240 Y + ++ + N Q + + + G V PV + Sbjct: 136 -------YEAIFEPNSGVLFSENCIQAYR----------ELAEAHGATVLTYTPVEDFEV 178 Query: 241 TRENVLVETLNHEMYEAKYVISAI---PPTLGMKIHFNPPLPMMRN 283 T + V ++T Y A ++ ++ L K+ PL R Sbjct: 179 TEDLVTIKTAKG-SYTANKLVVSMGAWNSKLLSKLDVEIPLQPYRQ 223 >1RP0-A nrPDB Length = 284 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 23/40 (57%), Gaps = 1/40 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSG-LNVVVLEARDRVGGRTY 44 DVVVVG G +G++AA + + + V ++E GG + Sbjct: 41 DVVVVGAGSAGLSAAYEISKNPNVQVAIIEQSVSPGGGAW 80 >3UP5-A nrPDB Length = 545 Score = 45.2 bits (105), Expect = 7e-05, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 50/126 (39%), Gaps = 4/126 (3%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 S D VV+G G++G+ A L++ +G+ V+ +EA + VGG T+ +D Sbjct: 7 SPALDAVVIGAGVTGIYQAFLINQAGMKVLGIEAGEDVGG-TWYWNRYPGCRLDTESYAY 65 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGP--FPPVWNPITYLDHNNFW 119 G + + E E+ R ++ + R F Y++++ W Sbjct: 66 GYFALKGIIPEWEWSENFASQPEMLRYVNRAAD-AMDVRKHYRFNTRVTAARYVENDRLW 124 Query: 120 RTMDDM 125 D Sbjct: 125 EVTLDN 130 >4REP-A nrPDB Length = 495 Score = 44.4 bits (103), Expect = 1e-04, Method: Composition-based stats. Identities = 45/291 (15%), Positives = 86/291 (29%), Gaps = 46/291 (15%) Query: 22 LLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV---GPTQNRILRLAKELGLE 78 L G +V + E D GG+ + + ++ DLG S +N +E+ Sbjct: 19 RLRHQGYSVTIFEKNDYAGGKLHAIEKDGYRF-DLGPSLFTLPHLVENLFALFPEEIIDF 77 Query: 79 TYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAP 138 YK + H+ F+ + + + I + A Sbjct: 78 GYKSKAIS--FHYFWDDGTLFKASTDSSQ------FIEDASKVFKEEKSTI---KKYLAK 126 Query: 139 LAEEWD-------NMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSAL-------- 183 +++ ++ + + F+ L T Sbjct: 127 SKSKYELTKSLFLEKSLHKATTYFSLDTVKAIVHAPFLGLNNTLNDENSKFKNPKLTQLF 186 Query: 184 -WFLWYVKQCGGTTRIISTTNGGQE-----RKFVGGSGQVSERIMDL---LGDRVKLERP 234 + Y T I T E GG ++S+ + +L +G + + Sbjct: 187 NRYATYNGSSPYQTPGIMTMIPHLELGLGTYYPDGGMHRISQSLFELAQKVGVKFRFRES 246 Query: 235 VIYIDQTRENVL-VETLNHEMYEAKYVISA---IPPTLGMKIHFNPPLPMM 281 V I ++ V VET N Y + V+S +P + + P P Sbjct: 247 VTNITTSKNKVTGVETKNG-SYLSDLVVSNMDIVPT--YRNLMKDVPAPEK 294 >6ER9-A nrPDB Length = 549 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 30/125 (24%), Positives = 41/125 (32%), Gaps = 5/125 (4%) Query: 5 CDVVVVGGGISGMAAAKLLH-DSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGP 63 D VV+G G G+ A LH + GL VV + D GG T+ D Sbjct: 10 VDAVVIGAGFGGIYAVHKLHNEQGLTVVGFDKADGPGG-TWYWNRYPGALSDTESHLYRF 68 Query: 64 TQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWN--PITYLDHNNFWRT 121 + +R L E+ + V + R F YL+ N W Sbjct: 69 SFDRDLLQDGTWKTTYITQPEILEYLESVVD-RFDLRRHFRFGTEVTSAIYLEDENLWEV 127 Query: 122 MDDMG 126 D G Sbjct: 128 STDKG 132 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 18/58 (31%), Positives = 25/58 (43%), Gaps = 5/58 (8%) Query: 224 LLGDRVKLERPVIYIDQTRENVL--VETLNHEMYEAKYVISAIPPTLGMKIHFNPPLP 279 L + V + L V T E+Y AKYV++A+ L I+F P LP Sbjct: 102 DLRRHFRFGTEVTSAIYLEDENLWEVSTDKGEVYRAKYVVNAV--GLLSAINF-PDLP 156 >3FPZ-A nrPDB Length = 326 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 28/153 (18%), Positives = 50/153 (32%), Gaps = 22/153 (14%) Query: 6 DVVVVGGGISGMAAAKLLHDS--GLNVVVLEARDRVGGRTY----------------TLR 47 DV++VG G SG++AA ++ + L V ++E+ GG ++ Sbjct: 67 DVIIVGAGSSGLSAAYVIAKNRPDLKVCIIESSVAPGGGSWLGGQLFSAMVMRKPAHLFL 126 Query: 48 NQKVKYVDLGGSYVGPTQNRIL---RLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFP 104 + + G YV + L+K L L K+ + V +G Sbjct: 127 QELEIPYEDEGDYVVVKHAALFISTVLSKVLQLPNVKLFNATCVEDLVTRPPTE-KGEVT 185 Query: 105 PVWNPITYLDHNNFWRTMDDMGREIPSDAPWKA 137 + T M + A +K Sbjct: 186 VAGVVTNWTLVTQAHGTQCSMDPNVIELAGYKN 218 >1NAA-A nrPDB Length = 541 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 21/72 (29%), Positives = 33/72 (45%), Gaps = 6/72 (8%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGP 63 D ++VG G G+ AA L ++G V++LE GG + + YV + G Sbjct: 2 PYDYIIVGAGPGGIIAADRLSEAGKKVLLLER----GGP--STKQTGGTYVAPWATSSGL 55 Query: 64 TQNRILRLAKEL 75 T+ I L + L Sbjct: 56 TKFDIPGLFESL 67 >4GCM-A nrPDB Length = 312 Score = 43.7 bits (101), Expect = 2e-04, Method: Composition-based stats. Identities = 22/96 (22%), Positives = 41/96 (42%), Gaps = 7/96 (7%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY-TLRNQKVKYVDLGGSYVGPT 64 D+ ++G G +GM AA + L V++E R GG+ T + + GP Sbjct: 8 DIAIIGAGPAGMTAAVYASRANLKTVMIE-RGIPGGQMANTEEVENFPGFE---MITGPD 63 Query: 65 -QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPF 99 ++ AK+ G Y+ +++ + + K F Sbjct: 64 LSTKMFEHAKKFG-AVYQYGDIKSVEDKGEYKVINF 98 >4RG3-A nrPDB Length = 548 Score = 43.3 bits (100), Expect = 2e-04, Method: Composition-based stats. Identities = 30/128 (23%), Positives = 42/128 (32%), Gaps = 5/128 (3%) Query: 2 SNKCDVVVVGGGISGMAAAKLL-HDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 ++ D VV+G G G+ A L H+ GL V + D GG T+ D Sbjct: 14 THTVDAVVIGAGFGGIYAVHKLHHELGLTTVGFDKADGPGG-TWYWNRYPGALSDTESHL 72 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWN--PITYLDHNNF 118 + +R L E+ + V + R F YLD N Sbjct: 73 YRFSFDRDLLQESTWKTTYITQPEILEYLEDVVD-RFDLRRHFKFGTEVTSALYLDDENL 131 Query: 119 WRTMDDMG 126 W D G Sbjct: 132 WEVTTDHG 139 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 19/58 (32%), Positives = 26/58 (44%), Gaps = 5/58 (8%) Query: 224 LLGDRVKLERPVIYIDQTRENVL--VETLNHEMYEAKYVISAIPPTLGMKIHFNPPLP 279 L K V + L V T + E+Y AKYV++A+ L I+F P LP Sbjct: 109 DLRRHFKFGTEVTSALYLDDENLWEVTTDHGEVYRAKYVVNAV--GLLSAINF-PNLP 163 >4USR-A nrPDB Length = 361 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 27/117 (23%), Positives = 47/117 (40%), Gaps = 10/117 (8%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG-RTYTLRNQKVKYVDLGGSYVGPT 64 DV+V+GGG + + A L + L+ ++L+ + GG + + ++ S G Sbjct: 9 DVIVIGGGQAALTTAYFLRRTSLSYLLLDEQPGPGGAWLHAWDSLRLFSPAAWSSIAGWP 68 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRT 121 E G T N+V + + Y F P + +T LD + WR Sbjct: 69 MPSPT----EPGNPTR--NDVIDYLRRYED-RYQFPIQRPVRVDTVTRLD--DLWRV 116 >2RGJ-A nrPDB Length = 402 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 14/40 (35%), Positives = 24/40 (60%), Gaps = 1/40 (2%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRV 39 MS D+++ G GI G++ A LH +G+ V +LE+ + Sbjct: 1 MSEPIDILIAGAGIGGLSCALALHQAGIGKVTLLESSSEI 40 >5MJK-A nrPDB Length = 327 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 30/62 (48%), Gaps = 5/62 (8%) Query: 1 MSNKC-DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT-YTLRNQKVKYVD--L 56 M+ K DVV++G G +GM AA S + ++LE R GG+ T + + + Sbjct: 20 MTEKKYDVVIIGSGPAGMTAAMYTARSEMKTLLLE-RGVPGGQMNNTAEIENYPGYETIM 78 Query: 57 GG 58 G Sbjct: 79 GP 80 Score = 32.9 bits (73), Expect = 0.36, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 21/34 (61%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 +++V+GGG S + A L G +V ++ RD++ Sbjct: 165 EILVIGGGDSAVEEALYLTRFGQSVTIMHRRDKL 198 >4UIR-A nrPDB Length = 646 Score = 43.3 bits (100), Expect = 3e-04, Method: Composition-based stats. Identities = 40/298 (13%), Positives = 84/298 (28%), Gaps = 64/298 (21%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGL----NVVVLEARDRVGGRTYTLRNQKVKYVDLGG 58 + + ++G GI+GM+AA G N+ LE GG N Y+ GG Sbjct: 61 DNSKIYIIGSGIAGMSAAYYFIRDGHVPAKNITFLEQLHIDGGSLDGAGNPTDGYIIRGG 120 Query: 59 SYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNF 118 + T + + +++ + P+ + D+++ Sbjct: 121 REMDMTYENLWDMFQDI-------------------PALEMPAPYSVLDEYRLINDNDSN 161 Query: 119 WRT--MDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAE 176 + + + EI + + D + + LL K + F + + Sbjct: 162 YSKARLINNKGEI---KDFSKFGLNKMDQLAIIRLLLKNKEELDDLTIEDYFSESFLKSN 218 Query: 177 THEVSALWFLW--YVKQCGGTTRIISTTNGGQERKFVGGSGQVS---------------- 218 W W + + + + G +S Sbjct: 219 ------FWTFWRTMFAFENWHSLLELKLYMHRFLHAIDGLNDLSSLVFPKYNQYDTFVTP 272 Query: 219 -ERIMDLLGDRVKLERPVIYID---QTRENVL---VETLNHEMYEA-----KYVISAI 264 + + G + L V +D T V+ + + + + YVI Sbjct: 273 LRKFLQEKGVNIHLNTLVKDLDIHINTEGKVVEGIITEQDGKEVKIPVGKNDYVIVTT 330 >4AP1-A nrPDB Length = 549 Score = 42.9 bits (99), Expect = 4e-04, Method: Composition-based stats. Identities = 19/55 (34%), Positives = 24/55 (43%), Gaps = 1/55 (1%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDL 56 + DVVVVG GI+G+ A GL V EA VGG + D+ Sbjct: 19 TTSYDVVVVGAGIAGLYAIHRFRSQGLTVRAFEAASGVGG-VWYWNRYPGARCDV 72 >5TR3-A nrPDB Length = 481 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 44/301 (14%), Positives = 78/301 (25%), Gaps = 61/301 (20%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT----------------- 43 M+ K DVVV+G G G AA GL +E G+ Sbjct: 4 MTQKFDVVVIGAGPGGYVAAIKAAQLGLKTACIEKYTDAEGKLALGGTCLNVGCIPSKAL 63 Query: 44 ----YTLRNQKVKYVDLG----------GSYVGPTQNRILRLAKELGLETYKVNEVERLI 89 + + K + G + VG + L G+ T I Sbjct: 64 LDSSWKYKEAKESFNVHGISTGEVKMDVAAMVGRKAGIVKNLTG--GVATLFKANGVTSI 121 Query: 90 HHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMK 149 + ++ N +IP + + + + + Sbjct: 122 QGHGKLLAGKKVEVTKADGTTEVIEAENVILASGSRPIDIPPAPVDQNVIVDSTGALEFQ 181 Query: 150 ---ELLDKLCWTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQ 206 + L + +L +++ L EV+ L L T Sbjct: 182 AVPKRLGVIGAGVIGLELGSVWARL-----GAEVTVLEALDTFLMAADTA---------- 226 Query: 207 ERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEM---YEAKYVISA 263 + +++ + G +KL V V V N E +I A Sbjct: 227 -------VSKEAQKTLTKQGLDIKLGARVTGSKVNGNEVEVTYTNAEGEQKITFDKLIVA 279 Query: 264 I 264 + Sbjct: 280 V 280 >2UZZ-A nrPDB Length = 372 Score = 42.5 bits (98), Expect = 4e-04, Method: Composition-based stats. Identities = 15/77 (19%), Positives = 27/77 (35%), Gaps = 1/77 (1%) Query: 220 RIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLP 279 ++ G PV I + V +ET + E Y+AK I + + P P Sbjct: 157 QLAKEAGCAQLFNCPVTAIRHDDDGVTIETADGE-YQAKKAIVCAGTWVKDLLPELPVQP 215 Query: 280 MMRNQMITRVPLGSVIK 296 + + + +K Sbjct: 216 VRKVFAWYQADGRYSVK 232 Score = 34.8 bits (78), Expect = 0.099, Method: Composition-based stats. Identities = 12/32 (37%), Positives = 20/32 (62%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 K D++++G G G AA +GLNV++ +A Sbjct: 2 KYDLIIIGSGSVGAAAGYYATRAGLNVLMTDA 33 >2TMD-A nrPDB Length = 729 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 39/229 (17%), Positives = 69/229 (30%), Gaps = 29/229 (12%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 NK V++VG G SG AA++L +SG V + + +++GG NQ LG Sbjct: 388 NKDSVLIVGAGPSGSEAARVLMESGYTVHLTDTAEKIGGHL----NQVAALPGLGEWSYH 443 Query: 63 PTQ--NRILRLAKELGLETYKVNEVE----RLIHHVKGKSYPFRGPFPPVWNPITYLDHN 116 +I +L K+ + + ++ + K G Sbjct: 444 RDYRETQITKLLKKNKESQLALGQKPMTADDVLQYGADKVIIATGA-------------- 489 Query: 117 NFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAE 176 W T A L ++ + + K+ T F+ + + Sbjct: 490 -RWNTDGTNCLTHDPIPGADASLPDQLTPEQVMDGKKKIGKRVVILNADTYFMAPSLAEK 548 Query: 177 ----THEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERI 221 HEV+ + + T + E RI Sbjct: 549 LATAGHEVTIVSGVHLANYMHFTLEYPNMMRRLHELHVEELGDHFCSRI 597 >3JSK-A nrPDB Length = 344 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 2/41 (4%) Query: 6 DVVVVGGGISGMAAAKLLH--DSGLNVVVLEARDRVGGRTY 44 D+V+VG G G++AA +L L + ++EA GG + Sbjct: 81 DIVIVGAGSCGLSAAYVLSTLRPDLRITIVEAGVAPGGGAW 121 >2VHY-A nrPDB Length = 377 Score = 42.5 bits (98), Expect = 5e-04, Method: Composition-based stats. Identities = 33/150 (22%), Positives = 59/150 (39%), Gaps = 20/150 (13%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR-DRVG-------GRTYTLRNQ----- 49 DVVV+G G +G AA++ + G V VL+ D++ GR +T + Sbjct: 167 EPADVVVIGAGTAGYNAARIANGMGATVTVLDINIDKLRQLDAEFCGRIHTRYSSAYELE 226 Query: 50 -KVKYVDL--GGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPV 106 VK DL G V + L ++ L + L+ + F G P Sbjct: 227 GAVKRADLVIGAVLVPGAKAPKL-VSNSL---VAHMKPGAVLVDIAIDQGGCFEGSRPTT 282 Query: 107 WNPITYLDHNNFWRTMDDMGREIPSDAPWK 136 ++ T+ H+ + + +M +P + + Sbjct: 283 YDHPTFAVHDTLFYCVANMPASVPKTSTYA 312 >5TUM-A nrPDB Length = 410 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 24/104 (23%), Positives = 42/104 (40%), Gaps = 8/104 (7%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE--ARDRVGGRTYTLRNQKVKYVDLGG 58 MS ++V+G G++G A L G + V++E A R GG+ +R G Sbjct: 22 MSKNIKILVIGAGVAGPAVCYWLRRFGFSPVLIEKYASIRKGGQALDVRGIATHIAREMG 81 Query: 59 SYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGP 102 Y + R V+ +++H +G+ + FR Sbjct: 82 IYDQICEMRTRIERGRF------VDSSGKVLHEEQGEKFGFRQD 119 Score = 31.7 bits (70), Expect = 0.78, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 215 GQVSERIMDLLGD-RVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISA 263 G + E +M + D + +I I+Q +NV V ++ + + VI+A Sbjct: 127 GDLVEILMKTIADVPCYFNQSIISIEQNADNVTVIFMDGRIEQYDLVIAA 176 >1V59-A nrPDB Length = 478 Score = 42.1 bits (97), Expect = 5e-04, Method: Composition-based stats. Identities = 15/41 (36%), Positives = 23/41 (56%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 ++ DVV++GGG +G AA G N +E R ++GG Sbjct: 2 INKSHDVVIIGGGPAGYVAAIKAAQLGFNTACVEKRGKLGG 42 >4JDR-A nrPDB Length = 474 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 43/272 (15%), Positives = 91/272 (33%), Gaps = 41/272 (15%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGR------TYTLRNQKVKYVDLG 57 K VVV+G G +G +AA D GL V++E + +GG + V V Sbjct: 6 KTQVVVLGAGPAGYSAAFRCADLGLETVIVERYNTLGGVCLNVGCIPSKALLHVAKVIEE 65 Query: 58 GSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNN 117 + ++ I+ + ++ + + + + G + +G V N + N Sbjct: 66 AKAL--AEHGIVFGEPKTDIDKIRTWKEKVINQLTGGLAGMAKGRKVKVVNGLGKFTGAN 123 Query: 118 FWRTMDDMGREI-------------PSDAPWKAPL-AEEWDNMTMKELLDKLCWTESAKQ 163 + G+ + P P+ WD+ EL + E Sbjct: 124 TLEVEGENGKTVINFDNAIIAAGSRPIQLPFIPHEDPRIWDSTDALELKE---VPERLLV 180 Query: 164 LATLFVNLCVTAETHEV-SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIM 222 + + L + H + S + + Q +I + + F + ++S++ Sbjct: 181 MGGGIIGLEMGTVYHALGSQIDVVEMFDQ------VIPAADKDIVKVF---TKRISKKF- 230 Query: 223 DLLGDRVKLERPVIYIDQTRENVLVETLNHEM 254 + LE V ++ + + V + Sbjct: 231 -----NLMLETKVTAVEAKEDGIYVTMEGKKA 257 >4C3X-A nrPDB Length = 530 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 17/40 (42%), Positives = 23/40 (57%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 +++CDV+VVG G + A GL +VLE DR GG Sbjct: 25 TSECDVLVVGSGGGALTGAYTAAAQGLTTIVLEKTDRFGG 64 >4K22-A nrPDB Length = 365 Score = 42.1 bits (97), Expect = 6e-04, Method: Composition-based stats. Identities = 18/33 (54%), Positives = 21/33 (63%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 DV +VGGG+ G+A A L SGL V VLE R Sbjct: 3 SVDVAIVGGGMVGLAVACGLQGSGLRVAVLEQR 35 >2VOU-A nrPDB Length = 397 Score = 41.7 bits (96), Expect = 8e-04, Method: Composition-based stats. Identities = 29/113 (25%), Positives = 45/113 (39%), Gaps = 16/113 (14%) Query: 1 MSNKCD-VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGS 59 MS D + VVGG ISG+ AA +L D+G++V V E + L V Sbjct: 1 MSPTTDRIAVVGGSISGLTAALMLRDAGVDVDVYERSPQP------LSGFGTGIV----- 49 Query: 60 YVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITY 112 Q ++ E G+E ++ + +V + G P W +Y Sbjct: 50 ----VQPELVHYLLEQGVELDSISVPSSSMEYVDALTGERVGSVPADWRFTSY 98 >5TWC-A nrPDB Length = 344 Score = 41.7 bits (96), Expect = 9e-04, Method: Composition-based stats. Identities = 21/92 (22%), Positives = 45/92 (48%), Gaps = 3/92 (3%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 DV ++GGG SG+ A+ ++V +++ + +GG+ +K+ + D+GG P Sbjct: 2 KDVTIIGGGPSGLYASFYAGLRDMSVRLIDVQSELGGKMRIYP-EKIIW-DIGGIAPKPC 59 Query: 65 QNRILRLAKELGLETYKVNEVERLIHHVKGKS 96 + IL+ + GL + + ++ K+ Sbjct: 60 -HEILKDTIKQGLYFKPEVHLNERVVDIRKKA 90 >3NIX-A nrPDB Length = 421 Score = 41.3 bits (95), Expect = 9e-04, Method: Composition-based stats. Identities = 27/137 (19%), Positives = 50/137 (36%), Gaps = 15/137 (10%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 K DV+V+G G +G AA L++ SG V ++E QK +G S + Sbjct: 4 EKVDVLVIGAGPAGTVAASLVNKSGFKVKIVE-------------KQKFPRFVIGESLLP 50 Query: 63 PTQNRI--LRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 + + + ++ + + + + F F WN + NF + Sbjct: 51 RCMEHLDEAGFLDAVKAQGFQQKFGAKFVRGKEIADFNFSDQFSNGWNWTWQVPRGNFDK 110 Query: 121 TMDDMGREIPSDAPWKA 137 T+ D D ++ Sbjct: 111 TLADEAARQGVDVEYEV 127 >1PS9-A nrPDB Length = 671 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 14/49 (28%), Positives = 23/49 (46%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK 52 K ++ VVG G +G+A A G V + +A +GG+ + K Sbjct: 373 KKNLAVVGAGPAGLAFAINAAARGHQVTLFDAHSEIGGQFNIAKQIPGK 421 >3IHG-A nrPDB Length = 535 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 14/34 (41%), Positives = 23/34 (67%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 ++ DV+VVG G+ G++ A L G+ V+V+E R Sbjct: 4 HEVDVLVVGAGLGGLSTAMFLARQGVRVLVVERR 37 >4ZN0-A nrPDB Length = 311 Score = 41.3 bits (95), Expect = 0.001, Method: Composition-based stats. Identities = 13/43 (30%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT 43 M++ D++++GGG +G+ A GL+ ++LE R+ + G+ Sbjct: 4 MASMYDLIIIGGGPAGLTAGIYAVRYGLDTLILE-RNEISGQI 45 Score = 31.7 bits (70), Expect = 0.90, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 21/51 (41%), Gaps = 1/51 (1%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV-GGRTYTLRNQKVKYVDL 56 V VVGGG S + A L V ++ RD + R R ++L Sbjct: 149 VAVVGGGNSAVTDALFLSKVAQKVYLVHRRDHLKAARVLQDRVDGTPNIEL 199 >6BRD-A nrPDB Length = 476 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 15/34 (44%), Positives = 20/34 (58%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 DV+VVGGG +G+ A L G+ V+VLE Sbjct: 3 DVIVVGGGPTGLMLAGELRLHGVRVLVLEKETEP 36 Score = 35.6 bits (80), Expect = 0.054, Method: Composition-based stats. Identities = 17/125 (13%), Positives = 44/125 (35%), Gaps = 5/125 (4%) Query: 214 SGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMK-- 271 + Q+ LG ++ R ++ + Q + V V+ + E A+YV+ ++ Sbjct: 101 TEQLLAEHATALGAEIRRGRALVGLRQDEDGVTVDLADGEQLRARYVVGCDGGRSTVRKL 160 Query: 272 --IHFNPPLPMMRNQMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLD 329 + F P P ++ + + + + + + + G M + V + Sbjct: 161 LGVAF-PGEPSRVETLLGEMEMTASQEELTSVMTEVRKTQQRFGAMPLGDGVFRVVVPAE 219 Query: 330 DTKPE 334 + Sbjct: 220 GVAED 224 >3FG2-P nrPDB Length = 404 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 18/45 (40%), Positives = 22/45 (48%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT 45 M +K VVV+G G G+ A GL V V+E RV R T Sbjct: 139 MPDKKHVVVIGAGFIGLEFAATARAKGLEVDVVELAPRVMARVVT 183 >5L46-A nrPDB Length = 841 Score = 41.0 bits (94), Expect = 0.001, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 26/43 (60%), Gaps = 1/43 (2%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLN-VVVLEARDRVGGRTY 44 ++ + V++GGG G++ A L +G+ VV+LE + G T+ Sbjct: 21 DRAETVIIGGGCVGVSLAYHLAKAGMKDVVLLEKSELTAGSTW 63 >1DOD-A nrPDB Length = 394 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 17/44 (38%), Positives = 26/44 (59%), Gaps = 2/44 (4%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--DRVGGRTYT 45 K V ++G G SG+ +LLH +G++ V+LE + D V GR Sbjct: 2 KTQVAIIGAGPSGLLLGQLLHKAGIDNVILERQTPDYVLGRIRA 45 >3R9U-A nrPDB Length = 315 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 22/40 (55%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYT 45 DV ++GGG +G++A GL VV+ + GG+ + Sbjct: 6 DVAIIGGGPAGLSAGLYATRGGLKNVVMFEKGMPGGQITS 45 >2GMH-A nrPDB Length = 584 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 21/96 (21%), Positives = 35/96 (36%), Gaps = 20/96 (20%) Query: 2 SNKCDVVVVGGGISGMAAAKLL------HDSGLNVVVLEARDRVGGRT--------YTLR 47 + + DVV+VG G +G++AA L H+ L V ++E +G T Sbjct: 33 AEEADVVIVGAGPAGLSAATRLKQLAAQHEKDLRVCLVEKAAHIGAHTLSGACLDPRAFE 92 Query: 48 NQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVN 83 + + G P + G+ T K Sbjct: 93 ELFPDWKEKGA----PLNTPVTE--DRFGILTEKYR 122 >4P9S-A nrPDB Length = 848 Score = 40.6 bits (93), Expect = 0.002, Method: Composition-based stats. Identities = 14/43 (32%), Positives = 27/43 (62%), Gaps = 1/43 (2%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGL-NVVVLEARDRVGGRTY 44 ++ + V++GGG G++ A L +G+ +VV+LE + G T+ Sbjct: 22 DRAETVIIGGGCVGVSLAYHLAKAGMRDVVLLEKSELTAGSTW 64 >2BS2-A nrPDB Length = 660 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 35/166 (21%), Positives = 63/166 (37%), Gaps = 9/166 (5%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 CD +V+GGG++G+ AA GL+ +VL R+++ Q LG S + Sbjct: 6 CDSLVIGGGLAGLRAAVATQQKGLSTIVL--SLIPVKRSHSAAAQGGMQASLGNSKMSDG 63 Query: 65 QNRILRLAKEL-GLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMD 123 N L + G + +V R+ + K+ P T + + ++ Sbjct: 64 DNEDLHFMDTVKGSDWGCDQKVARMFVNTAPKAIR---ELAAWGVPWTRIHKGDRMAIIN 120 Query: 124 DMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFV 169 I ++ ++ L D K+ + C+T A LF Sbjct: 121 AQKTTI-TEEDFRHGLIHSRDFGGTKKW--RTCYTADATGHTMLFA 163 >4EMJ-A nrPDB Length = 410 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 21/67 (31%), Positives = 30/67 (44%), Gaps = 9/67 (13%) Query: 8 VVVGGGISGMAAAKLLHDSGLNVVVLEARD---------RVGGRTYTLRNQKVKYVDLGG 58 ++VGGG+ G A GL+V +LEA D R+G L + V+LG Sbjct: 147 LIVGGGLIGCEVATTARKLGLSVTILEAGDELLVRVLGRRIGAWLRGLLTELGVQVELGT 206 Query: 59 SYVGPTQ 65 VG + Sbjct: 207 GVVGFSG 213 >2GV8-A nrPDB Length = 447 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 21/109 (19%), Positives = 34/109 (31%), Gaps = 9/109 (8%) Query: 5 CDVVVVGGGISGMAAAKLL--HDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 + ++G G SG+ AK L + V + E R GG + + + + Sbjct: 7 RKIAIIGAGPSGLVTAKALLAEKAFDQVTLFERRGSPGG-VWNYTSTLSNKLPV------ 59 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT 111 P+ N IL +G V G + P T Sbjct: 60 PSTNPILTTEPIVGPAALPVYPSPLYRDLQTNTPIELMGYCDQSFKPQT 108 >4IA5-A nrPDB Length = 591 Score = 40.2 bits (92), Expect = 0.002, Method: Composition-based stats. Identities = 40/208 (19%), Positives = 65/208 (31%), Gaps = 28/208 (13%) Query: 3 NKCDVVVVGGGISGMAAAKLL----HDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGG 58 +K ++G G++G++ A L G N+ +LE GG +V GG Sbjct: 21 DKKSAYIIGSGLAGLSTAVFLVRDAQMKGENIHILEELPVAGGSLDGADRPNAGFVVRGG 80 Query: 59 SYV---GPTQNRILRLAKELGLETYKV-------------NEVERLIHHVKGKSYPFRGP 102 + + R L + + RLI++ +G P G Sbjct: 81 REMENHFECLWDMYRSIPSLEVPGASYLDEYYWLDKEDPNSSNCRLIYN-RGDRLPSDGQ 139 Query: 103 F--PPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTES 160 + N I L E SD +K W M E L Sbjct: 140 YGLGKCANEIVKLIMTPEKEIEGQTIEEFFSDEFFKTNFWTYWSTMFAFEKWHSLAE--- 196 Query: 161 AKQLATLFVNLCVTAETHEVSALWFLWY 188 ++ A F++ + +AL F Y Sbjct: 197 MRRYAMRFIHHIDGLP--DFTALKFNKY 222 >6N7F-A nrPDB Length = 453 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 45/285 (15%), Positives = 86/285 (30%), Gaps = 45/285 (15%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLG--G 58 M D +V+GGG +G+A+A G V++ E ++ V+LG Sbjct: 4 MVIPYDYIVIGGGSAGIASANRAAMHGAKVLLAEGKE-----------IGGTCVNLGCVP 52 Query: 59 SYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLD--HN 116 V ++ + + K K++ F+ N Y+D H Sbjct: 53 KKVMWYGAQVADILGTYA---------KDYGFDFKEKAFDFK---QLKANRQAYIDRIHA 100 Query: 117 NFWRTMDDMGRE-IPSDAPWKAPLAEEWDN--MTMKELLDKLCWTESAKQLATLFVNLCV 173 ++ R + G + I A +K E T +L + + Sbjct: 101 SYERGFEQNGVDRIYDYAVFKDAHTVEIAGQLYTAPHILIATGGHPVFPDIEGAQYGISS 160 Query: 174 TA--ETHEVS-----------ALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSER 220 EV A+ + G T + + + + Sbjct: 161 DGFFALDEVPKRTAVVGAGYIAVELAGVLHALGSKTDLFIRHDRPLRSFDKTIVDVLVDE 220 Query: 221 IMDLLGDRVKLERPVIY-IDQTRENVLVETLNHEMYEAKYVISAI 264 + G R+ V + T E++ + + + E +I AI Sbjct: 221 MAVN-GPRLHTHAEVAKVVKNTDESLTLYLKDGQEVEVDQLIWAI 264 >4A6N-B nrPDB Length = 398 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 20/30 (66%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 +V ++GGG G+ AKLL +G++V V E Sbjct: 27 KNVAIIGGGPVGLTMAKLLQQNGIDVSVYE 56 >6JDK-A nrPDB Length = 544 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 14/50 (28%), Positives = 21/50 (42%), Gaps = 1/50 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVD 55 D ++VG G +G+ L G V + EA +GG + VD Sbjct: 19 DALIVGAGFNGIYQLHRLRQEGFKVRLFEAGADMGG-IWYWNCYPGARVD 67 >3RP7-A nrPDB Length = 407 Score = 39.8 bits (91), Expect = 0.003, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 19/30 (63%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 +V+G GI G++AA L SG++ V EA Sbjct: 25 KAIVIGAGIGGLSAAVALKQSGIDCDVYEA 54 >5UTH-A nrPDB Length = 319 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 13/52 (25%), Positives = 20/52 (38%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLG 57 DV+++G G +G AA + L +V E G T + G Sbjct: 17 DVIIIGSGPAGYTAAIYAARAQLKPLVFEGTQFGGALMTTTEVENYPGFREG 68 Score = 33.3 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 14/32 (43%), Positives = 18/32 (56%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 D+VVVGGG S M A L +V ++ RD Sbjct: 157 DIVVVGGGDSAMEEATFLTRFARSVTLIHRRD 188 >5TUK-A nrPDB Length = 408 Score = 39.4 bits (90), Expect = 0.003, Method: Composition-based stats. Identities = 23/97 (23%), Positives = 38/97 (39%), Gaps = 8/97 (8%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE--ARDRVGGRTYTLRNQKVKYVDLGGSYVGP 63 ++V+G GI+G A L G + +++E A R GG +R + G Y Sbjct: 27 KILVIGAGIAGPAVCYWLRRFGFSPILVERCANLRKGGHAVDIRGVAIDLAKSMGIYKKI 86 Query: 64 TQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFR 100 R V+ ++H KG+ + FR Sbjct: 87 CNMRTQVELGRY------VDAEGNILHEEKGERFGFR 117 Score = 31.7 bits (70), Expect = 0.77, Method: Composition-based stats. Identities = 13/63 (20%), Positives = 25/63 (39%), Gaps = 2/63 (3%) Query: 215 GQVSERIMDLLGD-RVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISAIPPT-LGMKI 272 G + + ++D +GD + V I Q +V V+ + VI A ++ Sbjct: 127 GDLVQILIDAMGDVPCHFNQWVESIKQRDNDVEVQFKDGRTELYDLVIGADGLHSTTRRM 186 Query: 273 HFN 275 F+ Sbjct: 187 VFD 189 >6J0Z-C nrPDB Length = 491 Score = 39.4 bits (90), Expect = 0.004, Method: Composition-based stats. Identities = 15/29 (51%), Positives = 21/29 (72%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DVVVVG G +G+ A L +G++VVVL+ Sbjct: 7 DVVVVGAGPTGLMLAGELRLAGVSVVVLD 35 >5YGQ-A nrPDB Length = 342 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 28/156 (17%), Positives = 59/156 (37%), Gaps = 12/156 (7%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGP 63 K DV++VG G G+ A L + +++ D+VGG+ L +K Y D+ G + Sbjct: 6 KTDVLIVGAGPCGLFAVFELGLLDVKAHLVDILDKVGGQCAELYPEKPIY-DIPGIPMVT 64 Query: 64 TQNRILRLAKELG--LETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRT 121 L +++ T+ ++E+ + + + V+ + Sbjct: 65 GHGLTEALMEQIKPFNPTFHLSEMVENVEKIGDPGFRVTTNAGKVFECTVLV-------V 117 Query: 122 MDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCW 157 G +P P P E ++ ++ + K+ Sbjct: 118 AAGGGSFLPKRPP--VPGVEAYEGTSVHYAVRKMED 151 >3T14-A nrPDB Length = 437 Score = 39.0 bits (89), Expect = 0.005, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 20/40 (50%), Gaps = 3/40 (7%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDS---GLNVVVLEARD 37 M VV++G G GM AA + ++ G V ++ A D Sbjct: 1 MRGSAHVVILGAGTGGMPAAYEMKEALGSGHEVTLISAND 40 >1NHQ-A nrPDB Length = 447 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 21/36 (58%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 +VVV+G G G+ AA+ +G V V++ DR G Sbjct: 151 NVVVIGSGYIGIEAAEAFAKAGKKVTVIDILDRPLG 186 >1LVL-A nrPDB Length = 458 Score = 38.6 bits (88), Expect = 0.006, Method: Composition-based stats. Identities = 14/36 (38%), Positives = 19/36 (52%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 +VVVGGG G+ G V V+EAR+R+ Sbjct: 171 PQHLVVVGGGYIGLELGIAYRKLGAQVSVVEARERI 206 >5Y77-A nrPDB Length = 473 Score = 38.6 bits (88), Expect = 0.007, Method: Composition-based stats. Identities = 15/67 (22%), Positives = 27/67 (40%), Gaps = 7/67 (10%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV----GGRTYTLRNQKVKYVDLGG 58 N V ++G G++G A+LL +G V + E R G R ++ + + G Sbjct: 7 NARQVTIIGAGLAGTLVARLLARNGWQVNLFERRPDPRIETGARGRSIN---LALAERGA 63 Query: 59 SYVGPTQ 65 + Sbjct: 64 HALRLAG 70 >5XGV-A nrPDB Length = 462 Score = 38.3 bits (87), Expect = 0.007, Method: Composition-based stats. Identities = 19/96 (19%), Positives = 34/96 (35%), Gaps = 5/96 (5%) Query: 189 VKQCGGTTRIISTTNGGQERKFVGGS--GQVSERI---MDLLGDRVKLERPVIYIDQTRE 243 + ++ +R F QV R+ LG RV+ + + QT + Sbjct: 69 FRMAHFAHIPLAPERVPGDRAFSFAVPHAQVERRLEERARSLGVRVRRSTEITSVRQTPD 128 Query: 244 NVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLP 279 V V T + E+ E Y++ ++ P P Sbjct: 129 GVQVTTGDGEVVEGAYLVGCDGSASLVREQAGIPFP 164 Score = 35.6 bits (80), Expect = 0.058, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 19/33 (57%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 V++ GGG G+ A L +G++ VVLE D Sbjct: 4 VIIAGGGPVGLMLACELGLAGVDTVVLERHDAP 36 >6BZ0-A nrPDB Length = 480 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 16/40 (40%), Positives = 20/40 (50%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVG 40 MS + D+VV+GGG G AA G V +E R G Sbjct: 4 MSQQFDLVVIGGGPGGYEAAIRAAQLGFKVACIEKRIHNG 43 Score = 31.7 bits (70), Expect = 0.75, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 16/34 (47%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 + V+G G+ G+ + G VVV EA D Sbjct: 183 PKRLGVIGAGVIGLELGSVWRRLGAEVVVFEAMD 216 >5U8W-A nrPDB Length = 481 Score = 38.3 bits (87), Expect = 0.009, Method: Composition-based stats. Identities = 15/34 (44%), Positives = 17/34 (50%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 MS K DVVV+G G G AA GL +E Sbjct: 4 MSQKFDVVVIGAGPGGYVAAIRAAQLGLKTACIE 37 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 11/35 (31%), Positives = 17/35 (48%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDR 38 + V+G G+ G+ + G V VLEA D+ Sbjct: 184 PKKLGVIGAGVIGLELGSVWARLGAEVTVLEALDK 218 >5KOX-A nrPDB Length = 476 Score = 37.9 bits (86), Expect = 0.010, Method: Composition-based stats. Identities = 15/55 (27%), Positives = 27/55 (49%), Gaps = 1/55 (1%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDL 56 S+ DV++ GGG +G+ A L G+ VVLE + + R + +++ Sbjct: 2 SHMIDVIIAGGGPTGLMLAGELRLHGVRTVVLEKEPTPNQHSRS-RGLHARSIEV 55 Score = 35.2 bits (79), Expect = 0.076, Method: Composition-based stats. Identities = 9/50 (18%), Positives = 20/50 (40%) Query: 214 SGQVSERIMDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISA 263 + ++ LG ++ V +DQ + V E + A+Y++ Sbjct: 104 TERLLTEHATELGAEIRRGCEVAGLDQDADGVTAELADGTRLRARYLVGC 153 >6DLL-A nrPDB Length = 398 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 14/44 (31%), Positives = 26/44 (59%), Gaps = 2/44 (4%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--DRVGGRTYT 45 K V ++G G SG+ +LLH +G++ +++E + + V GR Sbjct: 5 KTQVAIIGAGPSGLLLGQLLHKAGIDNIIVERQTAEYVLGRIRA 48 >1EBD-A nrPDB Length = 455 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 41/281 (14%), Positives = 89/281 (31%), Gaps = 41/281 (14%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGR-------------TYTLRNQKVK 52 + +VVG G G AA G V ++E + +GG + + R ++ K Sbjct: 5 ETLVVGAGPGGYVAAIRAAQLGQKVTIVE-KGNLGGVCLNVGCIPSKALISASHRYEQAK 63 Query: 53 YVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITY 112 + + G +N + AK ++ +K + V++L V+G +G + Y Sbjct: 64 HSEEMGIK---AENVTIDFAK---VQEWKASVVKKLTGGVEG---LLKGNKVEIVKGEAY 114 Query: 113 LDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLC 172 N R + A + + +L + + ++ L Sbjct: 115 FVDANTVRVV------NGDSAQTYTF---KNAIIATGSRPIELPNFKFSNRILDSTGALN 165 Query: 173 VTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQE------RKFVGGSGQVSERIMDLLG 226 + + + + + G T E F + ++ + G Sbjct: 166 LGEVPKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEILSGFEKQMAAIIKKRLKKKG 225 Query: 227 DRVKLERPVIYIDQTRENVLVETLNH---EMYEAKYVISAI 264 V ++ + V V + + +A YV+ + Sbjct: 226 VEVVTNALAKGAEEREDGVTVTYEANGETKTIDADYVLVTV 266 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 16/36 (44%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 +VV+GGG G+ + G V +LE + Sbjct: 170 PKSLVVIGGGYIGIELGTAYANFGTKVTILEGAGEI 205 >3ISH-A nrPDB Length = 311 Score = 37.9 bits (86), Expect = 0.011, Method: Composition-based stats. Identities = 18/70 (25%), Positives = 29/70 (41%), Gaps = 4/70 (5%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTL----RNQKVKYVDLGGSYV 61 D ++GGG +G++A G+ VL + GG+ VK V G ++ Sbjct: 3 DCAIIGGGPAGLSAGLYATRGGVKNAVLFEKGMPGGQITGSSEIENYPGVKEVVSGLDFM 62 Query: 62 GPTQNRILRL 71 P Q + R Sbjct: 63 QPWQEQCFRF 72 >4N9X-A nrPDB Length = 411 Score = 37.9 bits (86), Expect = 0.012, Method: Composition-based stats. Identities = 20/45 (44%), Positives = 27/45 (60%), Gaps = 3/45 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE---ARDRVGGRTYTLR 47 DVV+ GGG+ G+A A L SGL + VLE A + G+ + LR Sbjct: 5 DVVIAGGGMVGLALACGLQGSGLRIAVLEKQAAEPQTLGKGHALR 49 >4X4J-A nrPDB Length = 507 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 26/126 (20%), Positives = 38/126 (30%), Gaps = 19/126 (15%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 VV+ G G +G+ A L +G+ VVVLE R+ RT R Sbjct: 25 VVIAGAGPAGLMLAGELRLAGIGVVVLE---RLPARTGESRGLGFT-------------A 68 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPF---RGPFPPVWNPITYLDHNNFWRTMD 123 R + + + GL H G F G Sbjct: 69 RTMEVFDQRGLLRRFGEVQTSDQGHFGGIPVDFGLLDGAHQAAKTIPQSATEAVLEAWAG 128 Query: 124 DMGREI 129 ++G +I Sbjct: 129 ELGADI 134 >4CBQ-A nrPDB Length = 314 Score = 37.5 bits (85), Expect = 0.013, Method: Composition-based stats. Identities = 25/100 (25%), Positives = 37/100 (37%), Gaps = 1/100 (1%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 MSN DVV++G G + AA L S L V+ E GG + ++ + Sbjct: 1 MSNIHDVVIIGSGPAAHTAAIYLGRSSLKPVMYEGF-MAGGVAAGGQLTTTTIIENFPGF 59 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFR 100 L + E Y + I HV + PF+ Sbjct: 60 PNGIDGNELMMNMRTQSEKYGTTIITETIDHVDFSTQPFK 99 >2QA2-A nrPDB Length = 499 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 19/29 (65%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 V+VVG G +G+ A L G++V+VLE Sbjct: 15 VIVVGAGPAGLMLAGELRLGGVDVMVLEQ 43 >1KNR-A nrPDB Length = 540 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 31/215 (14%), Positives = 68/215 (31%), Gaps = 17/215 (7%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 + CDV+++G G +G++ A L D V+VL G T+ + D S Sbjct: 7 HSCDVLIIGSGAAGLSLALRLADQ-HQVIVLSKGPVTEGSTFYAQGGIAAVFDETDSIDS 65 Query: 63 PTQNRILR---LAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLD----- 114 ++ ++ + +E + + + + + F P +L Sbjct: 66 HVEDTLIAGAGICDRHAVE-FVASNARSCVQWLIDQGVLFDTHIQPNGEESYHLTREGGH 124 Query: 115 -HNNFWRTMDDMGREIPSD---APWKAPLAEEWDNMTMKELL--DKLCWTESAKQLATLF 168 H D GRE+ + P + +L+ DK+ + +++ + Sbjct: 125 SHRRILHAADATGREVETTLVSKALNHPNIRVLERTNAVDLIVSDKIGLPGT-RRVVGAW 183 Query: 169 VNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTN 203 V A + + + + Sbjct: 184 VWNRNKETVETCHAKAVVLATGGASKVYQYTTNPD 218 >3LZX-A nrPDB Length = 332 Score = 37.5 bits (85), Expect = 0.014, Method: Composition-based stats. Identities = 31/150 (20%), Positives = 57/150 (38%), Gaps = 9/150 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D+ ++GGG G+ A +V ++E+ ++GG+ L +K Y G + Sbjct: 9 DITIIGGGPVGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKI---- 64 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 R L L + K ++ L V+ G F V N T+ ++ Sbjct: 65 -RAQELINNLKEQMAKFDQTICLEQAVESVEKQADGVFKLVTNEETH--YSKTVIITAGN 121 Query: 126 GREIPSDAPWKAPLAEEWDNMTMKELLDKL 155 G P + AE+++ + +D L Sbjct: 122 GAFKPRKLELEN--AEQYEGKNLHYFVDDL 149 >3NTA-A nrPDB Length = 574 Score = 37.5 bits (85), Expect = 0.015, Method: Composition-based stats. Identities = 15/39 (38%), Positives = 21/39 (53%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 M+N VVGGG G+ + LH G+ +LE D+V Sbjct: 148 MNNVEHATVVGGGFIGLEMMESLHHLGIKTTLLELADQV 186 >4B1B-A nrPDB Length = 542 Score = 37.5 bits (85), Expect = 0.016, Method: Composition-based stats. Identities = 20/73 (27%), Positives = 33/73 (45%), Gaps = 11/73 (15%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGS--YVGP 63 D VV+GGG GMA+AK G V++ + Y + + +GG+ VG Sbjct: 44 DYVVIGGGPGGMASAKEAAAHGARVLLFD---------YVKPSSQGTKWGIGGTCVNVGC 94 Query: 64 TQNRILRLAKELG 76 +++ A +G Sbjct: 95 VPKKLMHYAGHMG 107 >6AON-A nrPDB Length = 478 Score = 37.1 bits (84), Expect = 0.017, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 20/35 (57%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 MS + DVVV+G G G AA G++V ++A Sbjct: 4 MSKQFDVVVIGAGPGGYIAAIRAAQLGMSVACIDA 38 Score = 31.7 bits (70), Expect = 0.71, Method: Composition-based stats. Identities = 9/32 (28%), Positives = 15/32 (46%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 + V+G G+ G+ + G V +LEA Sbjct: 186 PKKLGVIGAGVIGLEMGSVWRRLGAEVTILEA 217 >6CMZ-A nrPDB Length = 466 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 46/284 (16%), Positives = 88/284 (30%), Gaps = 50/284 (17%) Query: 8 VVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG--------------RTYTLRNQKVKY 53 +V+GGG G AA G+ V++E RDR+GG Q + Sbjct: 12 LVIGGGPGGYVAAIRAGQLGIPTVLVE-RDRLGGTCLNIGCIPSKALIHVADAFEQACGH 70 Query: 54 VDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYL 113 G + I +AK + + V+ + R + + KS + Sbjct: 71 AGEGALGIRVRAPEI-DIAKSVAWKDGIVDRLTRGVGALLKKSGVRVLHGEARVIDGKTV 129 Query: 114 DHNNFW---RTMDDMGR--------EIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAK 162 + + R + E+PS P+ + D ++ L +L Sbjct: 130 EVVSAGHAVRIGCEHLLLATGSEPVELPS-MPFGGHVVSSTDALSPATLPKRLVV--VGA 186 Query: 163 QLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIM 222 L + + +VS + R++ + R ++ R+ Sbjct: 187 GYIGLELGIVYRKLGVDVSVVEAAE---------RVLPAYDAELVRPVADSLARLGVRLW 237 Query: 223 DLLGDRVKLERPVIYIDQTRENVLVETLNHEMYE--AKYVISAI 264 L V+ +D+ V V+ + A V+ A+ Sbjct: 238 --------LGHKVLGLDKHG-AVRVQAADGAEQTLPADRVLVAV 272 Score = 37.1 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 20/36 (55%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 +VVVG G G+ + G++V V+EA +RV Sbjct: 178 PKRLVVVGAGYIGLELGIVYRKLGVDVSVVEAAERV 213 >2A87-A nrPDB Length = 335 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 20/53 (37%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLG 57 DV+V+G G +G AA + L +V E G T + G Sbjct: 15 RDVIVIGSGPAGYTAALYAARAQLAPLVFEGTSFGGALMTTTDVENYPGFRNG 67 >5J7X-A nrPDB Length = 549 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 27/126 (21%), Positives = 44/126 (34%), Gaps = 8/126 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDS-GLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 D +++G G SG+ L D L V + EA +GG T+ VD + + Sbjct: 14 DALIIGSGFSGIYLLHKLRDELKLKVKIFEAESDIGG-TWNNNRYPGARVDCPVPFYAYS 72 Query: 65 QNRILRLAKELGLETYK-VNEVERLIHHVKGKSYPFRGP--FPPVWNPITYLDHNNFWRT 121 + + E Y E++ HV + R F N T+ + W Sbjct: 73 LPEVWQ--SWNWTELYPNQKEIKSYFDHV-DRVLDVRKDCLFHSRVNEGTFDEATGRWTV 129 Query: 122 MDDMGR 127 G+ Sbjct: 130 WTTDGK 135 >1C0L-A nrPDB Length = 363 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 28/151 (18%), Positives = 58/151 (38%), Gaps = 15/151 (9%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 M ++ VVV+G G+ G+++A +L G +V +L ARD + + + G ++ Sbjct: 3 MHSQKRVVVLGSGVIGLSSALILARKGYSVHIL-ARDLP--EDVSSQTFASPWA--GANW 57 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHV-KGKSYPFRGPFPPVWNPITYLDHNNFW 119 + L ++ + ++ + V G + +G N L H W Sbjct: 58 -----TPFMTLTDGPRQAKWEESTFKKWVELVPTGHAMWLKGTRRFAQNEDGLLGH---W 109 Query: 120 RTMDD-MGREIPSDAPWKAPLAEEWDNMTMK 149 R +PS + +D +++ Sbjct: 110 YKDITPNYRPLPSSECPPGAIGVTYDTLSVH 140 >3COX-A nrPDB Length = 507 Score = 37.1 bits (84), Expect = 0.019, Method: Composition-based stats. Identities = 12/52 (23%), Positives = 22/52 (42%), Gaps = 5/52 (9%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV 54 ++ +V+G G G AA L +G+ ++E GR++ K Sbjct: 10 DRVPALVIGSGYGGAVAALRLTQAGIPTQIVEM-----GRSWDTPGSDGKIF 56 >5J5Z-A nrPDB Length = 496 Score = 37.1 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 13/36 (36%), Positives = 17/36 (47%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 DV V+G G G AA G V +E + +GG Sbjct: 30 DVTVIGSGPGGYVAAIKAAQLGFKTVCIEKNETLGG 65 Score = 32.5 bits (72), Expect = 0.41, Method: Composition-based stats. Identities = 11/38 (28%), Positives = 18/38 (47%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 +VV+G G+ G+ + G +V +E VGG Sbjct: 200 PEKMVVIGAGVIGVELGSVWQRLGADVTAVEFLGHVGG 237 >5EZ7-A nrPDB Length = 392 Score = 37.1 bits (84), Expect = 0.020, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 24/40 (60%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT 43 D+++VGGGI+G+ L +G V++E+ GG++ Sbjct: 7 STDILIVGGGIAGLWLNARLRRAGYATVLVESASLGGGQS 46 >5UWY-A nrPDB Length = 308 Score = 36.7 bits (83), Expect = 0.022, Method: Composition-based stats. Identities = 15/51 (29%), Positives = 24/51 (47%), Gaps = 2/51 (3%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRT-YTLRNQKVKYVD 55 D +++G G +GM AA S L+V ++E GG+ T + D Sbjct: 6 DTLIIGSGPAGMTAALYAARSNLSVAIIEQGA-PGGQMNNTFDIENYPGYD 55 >5X6R-A nrPDB Length = 420 Score = 36.7 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 30/186 (16%), Positives = 58/186 (31%), Gaps = 25/186 (13%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 S V ++G G+ G AA G NV + + R R T +N+ +K ++L Sbjct: 26 SMSESVAIIGAGLVGCLAALAFSKEGYNVTLYDFRQDP--RLDTTKNKNLKSINLA---- 79 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRG----PFPPVWNPITYLDHNN 117 G++ K + H+ P +G Y H Sbjct: 80 ----------ISARGIDALK-SIDPDACEHILQDMIPMKGRMIHDLKGRQESQLYGLH-- 126 Query: 118 FWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAET 177 ++ + R + +++ + L K+ WT+ + T T Sbjct: 127 -GEAINSINRSVLNNSLLDELEKST-TELKFGHKLVKIEWTDDKQICHFAIGEDLKTPHT 184 Query: 178 HEVSAL 183 + + Sbjct: 185 EKYDFV 190 >5ZYN-B nrPDB Length = 471 Score = 36.7 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 14/41 (34%), Positives = 23/41 (56%), Gaps = 1/41 (2%) Query: 2 SNKCDVVVVGGGISGMAAAKLL-HDSGLNVVVLEARDRVGG 41 S K VVV+G G++G+ + L + VV+L+ +GG Sbjct: 2 SMKQPVVVIGSGLAGLTTSNRLISKYRIPVVLLDKAASIGG 42 >3AB1-A nrPDB Length = 360 Score = 36.7 bits (83), Expect = 0.024, Method: Composition-based stats. Identities = 48/267 (17%), Positives = 93/267 (34%), Gaps = 25/267 (9%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 + D+ ++GGG +G+ AA + ++ ++E+ ++GG+ L +K Y G Sbjct: 13 DMRDLTIIGGGPTGIFAAFQCGMNNISCRIIESMPQLGGQLAALYPEKHIYDVAG----F 68 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTM 122 P I L + L + + N L V + G F N + + Sbjct: 69 PEVPAI-DLVESLWAQAERYNPDVVLNETVTKYTKLDDGTFETRTN-TGNVYRSRAVLIA 126 Query: 123 DDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSA 182 +G P K P D++T + + E K + V + Sbjct: 127 AGLGA----FEPRKLPQLGNIDHLTGSSVYYAVKSVEDFKGKRVVIVGG--GDSALD--- 177 Query: 183 LWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTR 242 W + +K ++ + G E + G + ER V LE V I+++ Sbjct: 178 -WTVGLIKNAAS----VTLVHRGHEFQGHGKTAHEVERARANGTIDVYLETEVASIEESN 232 Query: 243 ENVL---VETLNHE--MYEAKYVISAI 264 + + + + EA ++ I Sbjct: 233 GVLTRVHLRSSDGSKWTVEADRLLILI 259 >3LAD-A nrPDB Length = 476 Score = 36.7 bits (83), Expect = 0.026, Method: Composition-based stats. Identities = 13/33 (39%), Positives = 17/33 (51%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 S K DV+V+G G G AA GL ++E Sbjct: 1 SQKFDVIVIGAGPGGYVAAIKSAQLGLKTALIE 33 Score = 33.3 bits (74), Expect = 0.27, Method: Composition-based stats. Identities = 28/130 (21%), Positives = 44/130 (33%), Gaps = 11/130 (8%) Query: 9 VVGGGISGMAAAKLLHDSGLNVVVLEARDR--------VGGRTYTLRNQKVKYVDLGGSY 60 V+G G+ G+ + G V VLEA D+ V + ++ + LG Sbjct: 185 VIGAGVIGLELGSVWARLGAEVTVLEAMDKFLPAVDEQVAKEAQKILTKQGLKILLGARV 244 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 G K + E K ++LI V + P + +T LD F Sbjct: 245 TGTEVKNKQVTVKFVDAEGEKSQAFDKLIVAVGRR--PVTTDLLAADSGVT-LDERGFIY 301 Query: 121 TMDDMGREIP 130 D +P Sbjct: 302 VDDYCATSVP 311 >6GAR-A nrPDB Length = 349 Score = 36.3 bits (82), Expect = 0.030, Method: Composition-based stats. Identities = 14/53 (26%), Positives = 26/53 (49%), Gaps = 2/53 (3%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGG 58 DV V+GGG +G+ +A + ++E +GG+ + + D+GG Sbjct: 8 DVTVIGGGPAGLYSAFYSGLREMRTKIIEFHPHLGGKIHVY--PEKMIWDVGG 58 >6A37-A nrPDB Length = 552 Score = 36.3 bits (82), Expect = 0.033, Method: Composition-based stats. Identities = 24/124 (19%), Positives = 43/124 (34%), Gaps = 7/124 (5%) Query: 6 DVVVVGGGISGMAAAKLLH-DSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 D +++G G G+ + K L D L V + VGG T+ D Sbjct: 28 DAIIIGAGFGGLYSLKKLRDDFNLKVRAFDRATEVGG-TWFWNQYPGALSDSETHLY--C 84 Query: 65 QNRILRLAKELGLETYKVNE--VERLIHHVKGKSYPFRGPFPPVWNPITYLD-HNNFWRT 121 + L +E+ ++ +++ V + V K + Y D N+FW Sbjct: 85 YSWDKELLQEMEIKRKYISQPDVLAYLKRVADKHDLRKDIQFETGIRSAYFDEENSFWNV 144 Query: 122 MDDM 125 + Sbjct: 145 TTEN 148 >2E5V-A nrPDB Length = 472 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 9/28 (32%), Positives = 17/28 (60%) Query: 9 VVGGGISGMAAAKLLHDSGLNVVVLEAR 36 ++G GI+G++A L +G V ++ R Sbjct: 4 IIGSGIAGLSAGVALRRAGKKVTLISKR 31 >5TUF-A nrPDB Length = 409 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 25/50 (50%), Gaps = 1/50 (2%) Query: 215 GQVSERIMDLLGD-RVKLERPVIYIDQTRENVLVETLNHEMYEAKYVISA 263 G + E +M + D + ++ VI I+Q ++V V + + VI+A Sbjct: 127 GDLVEILMKAIADIPCEFKQSVIKIEQNEDSVTVTYKDGRVENYDLVIAA 176 >3SM8-A nrPDB Length = 381 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 14/35 (40%), Positives = 19/35 (54%), Gaps = 1/35 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVG 40 D +V+G GI+G + L G VVVLE + G Sbjct: 11 DYLVIGAGIAGASTGYWLSAHG-RVVVLEREAQPG 44 >1FOH-A nrPDB Length = 664 Score = 36.3 bits (82), Expect = 0.035, Method: Composition-based stats. Identities = 20/84 (23%), Positives = 36/84 (42%), Gaps = 11/84 (13%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT 64 CDV++VG G +G+ AA++L + R + + + + K + + Sbjct: 8 CDVLIVGAGPAGLMAARVLSEY--------VRQKPDLKVRIIDKRSTKVYNGQADGL--- 56 Query: 65 QNRILRLAKELGLETYKVNEVERL 88 Q R L K LGL ++E + Sbjct: 57 QCRTLESLKNLGLADKILSEANDM 80 >4K2X-A nrPDB Length = 523 Score = 36.3 bits (82), Expect = 0.036, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 17/29 (58%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DVV+ G G +G+ A L +G +VLE Sbjct: 24 DVVIAGAGPTGLMLACELRLAGARTLVLE 52 >6C6P-A nrPDB Length = 458 Score = 36.0 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 19/32 (59%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 N +V++VG G+ G A A +L G V V+E Sbjct: 6 NDPEVIIVGAGVLGSALAAVLSRDGRKVTVIE 37 >4MOP-A nrPDB Length = 633 Score = 36.0 bits (81), Expect = 0.037, Method: Composition-based stats. Identities = 13/34 (38%), Positives = 18/34 (52%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 M K DVV+VG G G A+ L +G V + + Sbjct: 43 MDIKYDVVIVGSGPIGCTYARELVGAGYKVAMFD 76 >6BWT-A nrPDB Length = 319 Score = 36.0 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 14/64 (21%), Positives = 27/64 (42%), Gaps = 2/64 (3%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 M+N ++++G G +G AA + L V++ + GG+ T + Sbjct: 4 MANHHKLIILGSGPAGYTAAIYAARANLKPVIITGM-QPGGQL-TTTTDVYNWPGEPDGI 61 Query: 61 VGPT 64 +GP Sbjct: 62 MGPE 65 >3QJ4-A nrPDB Length = 342 Score = 36.0 bits (81), Expect = 0.038, Method: Composition-based stats. Identities = 19/65 (29%), Positives = 30/65 (46%), Gaps = 5/65 (7%) Query: 7 VVVVGGGISG-MAAA--KLLHDSGLNVVVLEARDRVGGRTYTLRNQKVK--YVDLGGSYV 61 V++VG G++G + AA + L + V + D GGR T + DLG Y+ Sbjct: 4 VLIVGAGMTGSLCAALLRRQTSGPLYLAVWDKADDSGGRMTTACSPHNPQCTADLGAQYI 63 Query: 62 GPTQN 66 T + Sbjct: 64 TCTPH 68 >6GAS-A nrPDB Length = 331 Score = 36.0 bits (81), Expect = 0.040, Method: Composition-based stats. Identities = 26/107 (24%), Positives = 42/107 (39%), Gaps = 5/107 (4%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D+ ++GGG +G+ A +V ++E+ ++GG+ L +K Y G V Sbjct: 11 DITIIGGGPTGLFTAFYGGMRQASVKIIESLPQLGGQLSALYPEKYIYDVAGFPKV---- 66 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITY 112 R L L + K + L V G F V N T+ Sbjct: 67 -RAQELVDNLKEQMKKFDPTVCLEEAVDTLEKQADGIFKLVTNKQTH 112 >4YNU-A nrPDB Length = 571 Score = 36.0 bits (81), Expect = 0.043, Method: Composition-based stats. Identities = 15/35 (42%), Positives = 23/35 (65%), Gaps = 1/35 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSG-LNVVVLEARDRV 39 D +VVGGG SG+ A L ++ ++V++LEA V Sbjct: 7 DYIVVGGGTSGLVVANRLSENPDVSVLLLEAGASV 41 >2BRY-A nrPDB Length = 497 Score = 36.0 bits (81), Expect = 0.045, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 17/29 (58%) Query: 8 VVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 +VVG G G+ AA L G VV++E R Sbjct: 96 LVVGAGPCGLRAAVELALLGARVVLVEKR 124 >4TXK-A nrPDB Length = 615 Score = 36.0 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 13/29 (44%), Positives = 17/29 (58%) Query: 8 VVVGGGISGMAAAKLLHDSGLNVVVLEAR 36 +VVG G G+ AA L G VV++E R Sbjct: 88 LVVGAGPCGLRAAVELALLGARVVLVEKR 116 >4HA6-A nrPDB Length = 508 Score = 36.0 bits (81), Expect = 0.047, Method: Composition-based stats. Identities = 20/80 (25%), Positives = 34/80 (42%), Gaps = 15/80 (18%) Query: 5 CDVVVVGGGISG-MAAAKLLHDSGLNVVVLEARDRVG--------------GRTYTLRNQ 49 CD+V+VGGG +G + AA+L D V+++EA + GR+Y + Sbjct: 2 CDIVIVGGGSAGSLLAARLSEDPDSRVLLIEAGEEPTDPDIWNPAAWPALQGRSYDWDYR 61 Query: 50 KVKYVDLGGSYVGPTQNRIL 69 G + R++ Sbjct: 62 TEAQAGTAGRAHHWARGRLI 81 >3CP8-A nrPDB Length = 641 Score = 35.6 bits (80), Expect = 0.057, Method: Composition-based stats. Identities = 24/99 (24%), Positives = 41/99 (41%), Gaps = 15/99 (15%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 S+ DV+VVG G +G AA + GL+ +++ T V + + Sbjct: 19 SHMYDVIVVGAGHAGCEAALAVARGGLHCLLI-----------TSDLSAVARMSCNPAIG 67 Query: 62 GPTQNRILRLAKELGLETYKVNEVE----RLIHHVKGKS 96 G + +I R LG E K + R+++ KG + Sbjct: 68 GVAKGQITREIDALGGEMGKAIDATGIQFRMLNRSKGPA 106 >2R9Z-A nrPDB Length = 463 Score = 35.6 bits (80), Expect = 0.060, Method: Composition-based stats. Identities = 12/36 (33%), Positives = 17/36 (47%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 V ++G G G+ A LL G V V+ DR+ Sbjct: 166 PKRVAIIGAGYIGIELAGLLRSFGSEVTVVALEDRL 201 Score = 34.0 bits (76), Expect = 0.14, Method: Composition-based stats. Identities = 13/41 (31%), Positives = 24/41 (58%), Gaps = 1/41 (2%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 M+ D++ +GGG G+A A+ G V ++E++ +GG Sbjct: 1 MTQHFDLIAIGGGSGGLAVAEKAAAFGKRVALIESKA-LGG 40 >4P2C-A nrPDB Length = 297 Score = 35.6 bits (80), Expect = 0.062, Method: Composition-based stats. Identities = 29/173 (16%), Positives = 55/173 (31%), Gaps = 27/173 (15%) Query: 314 TMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEERLKKLCELYAKVLG 373 ++ A + ++ + E + A + + +A + ++ +E ++ A V Sbjct: 133 HSLVSSYLALMEFSGNTMTREASRAVLRFVTVTAQALRFRQIQRE--FRQALSETAPV-- 188 Query: 374 SLEALEPVHYEEK-NWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDRIYFAGTETATHW 432 + P + NW G + P +Y V RI F Sbjct: 189 --YTMTPEDVDLTLNW-------GRISNVLP-----EYRGEAGVRVGRISFNNISAILGT 234 Query: 433 SGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTTFLERH 485 + G R+ R + PE +I + D P IT T E + Sbjct: 235 VAVILNCHHQGARSVRAVNEESQ--PECQI------TGDRPVIKITNTLWESN 279 >2EQ6-A nrPDB Length = 464 Score = 35.2 bits (79), Expect = 0.066, Method: Composition-based stats. Identities = 15/36 (41%), Positives = 21/36 (58%), Gaps = 1/36 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 D++V+G G G AA GL V+ +EA + VGG Sbjct: 8 DLIVIGTGPGGYHAAIRAAQLGLKVLAVEAGE-VGG 42 >1GAL-A nrPDB Length = 583 Score = 34.8 bits (78), Expect = 0.083, Method: Composition-based stats. Identities = 11/63 (17%), Positives = 31/63 (49%), Gaps = 16/63 (25%) Query: 1 MSNKCDV-------VVVGGGISGMAAAKLLHDSG-LNVVVLEARDRVGGRTYTLRNQKVK 52 +++ DV ++ GGG++G+ A L ++ ++V+V+E+ + + + Sbjct: 9 LTDPKDVSGRTVDYIIAGGGLTGLTTAARLTENPNISVLVIESG--------SYESDRGP 60 Query: 53 YVD 55 ++ Sbjct: 61 IIE 63 >1DXL-A nrPDB Length = 470 Score = 34.8 bits (78), Expect = 0.095, Method: Composition-based stats. Identities = 44/292 (15%), Positives = 91/292 (31%), Gaps = 51/292 (17%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG---------------RTYTL 46 S++ DVV++GGG G AA G +E R +GG ++ Sbjct: 4 SDENDVVIIGGGPGGYVAAIKAAQLGFKTTCIEKRGALGGTCLNVGCIPSKALLHSSHMY 63 Query: 47 RNQKVKYVDLG----------GSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKS 96 K + + G + +G + L + G+E + Sbjct: 64 HEAKHSFANHGVKVSNVEIDLAAMMGQKDKAVSNLTR--GIEGLFKKNKVTYVKGYGKFV 121 Query: 97 YPFRGPFPPVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLC 156 P + T + + + +P + + + + E+ KL Sbjct: 122 SPSEISVDTIEGENTVVKGKHIIIATGSDVKSLPGVTIDEKKIVSSTGALALSEIPKKLV 181 Query: 157 WTESAKQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQ 216 L + EV+ + F + I+ T + ++F Sbjct: 182 V--IGAGYIGLEMGSVWGRIGSEVTVVEF---------ASEIVPTMDAEIRKQF------ 224 Query: 217 VSERIMDLLGDRVKLERPVIYIDQTRENVLVETL-----NHEMYEAKYVISA 263 +R ++ G + KL+ V+ +D + + V + + EA V+ + Sbjct: 225 --QRSLEKQGMKFKLKTKVVGVDTSGDGVKLTVEPSAGGEQTIIEADVVLVS 274 >2ZBW-A nrPDB Length = 335 Score = 34.8 bits (78), Expect = 0.10, Method: Composition-based stats. Identities = 14/52 (26%), Positives = 26/52 (50%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKY 53 ++ DV++VG G +G+ A + GL+ ++ GG+ L +K Y Sbjct: 3 ADHTDVLIVGAGPTGLFAGFYVGMRGLSFRFVDPLPEPGGQLTALYPEKYIY 54 >5W4C-A nrPDB Length = 371 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 14/47 (29%), Positives = 20/47 (42%), Gaps = 4/47 (8%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEA----RDRVGGRTYTLRN 48 VV++G G G AA L + L V+ E GG+ T + Sbjct: 32 KVVIIGSGPGGHTAAIYLARANLEPVLYEGMLANGFAPGGQLTTTTD 78 >6BPY-A nrPDB Length = 374 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 16/61 (26%), Positives = 25/61 (40%), Gaps = 7/61 (11%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEA----RDRVGGRTYT---LRNQKVKYVDLGG 58 VV++G G + AA L + L V+ E GG+ T + N +GG Sbjct: 6 KVVIIGSGPAAHTAAIYLSRAELKPVLYEGMLANGTAAGGQLTTTTDIENFPGFPDGIGG 65 Query: 59 S 59 + Sbjct: 66 A 66 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 17/31 (54%) Query: 9 VVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 V+GGG S A L G +V VL RD++ Sbjct: 163 VIGGGDSAAEEAMFLAKYGSSVTVLVRRDKL 193 >4NTC-A nrPDB Length = 335 Score = 34.4 bits (77), Expect = 0.11, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 17/31 (54%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 DV+++G G +G++ A L VV ++ Sbjct: 15 VDVLIIGAGPAGLSTATGLARQLHTAVVFDS 45 >5TUL-A nrPDB Length = 406 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 15/54 (27%), Positives = 23/54 (42%), Gaps = 2/54 (3%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE--ARDRVGGRTYTLRNQKVK 52 M + ++V+G I+G A L+ G ++E R GG LR V Sbjct: 22 MPHTKKILVIGASIAGPALCYWLNHYGFQPTLVEKNQSTRKGGYAIDLRGIAVD 75 >3IP1-A nrPDB Length = 404 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 23/96 (23%), Positives = 43/96 (44%), Gaps = 9/96 (9%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVL----EARDRVG---GRTYTLRNQKVKYVDLGG 58 +VV++GGG G+AA +L +G + V+L E R + G + + K +V+ Sbjct: 216 NVVILGGGPIGLAAVAILKHAGASKVILSEPSEVRRNLAKELGADHVIDPTKENFVEAVL 275 Query: 59 SYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKG 94 Y ++ A G+ ++E +I +G Sbjct: 276 DYTNGLGAKLFLEAT--GVPQLVWPQIEEVIWRARG 309 >5X68-A nrPDB Length = 391 Score = 34.4 bits (77), Expect = 0.12, Method: Composition-based stats. Identities = 34/161 (21%), Positives = 54/161 (33%), Gaps = 29/161 (18%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGP 63 + V V+GGG+ G A L + V EAR+ T + + ++L S Sbjct: 14 RKKVAVIGGGLVGSLQACFLAKRNFQIDVYEARED----TRVATFTRGRSINLALS---- 65 Query: 64 TQNRILRLAKELGLETYKVNE----VERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFW 119 +R + K +GLE V++ R+IH + GK + Sbjct: 66 --HRGRQALKAVGLEDQIVSQGIPMRARMIHSLSGKKSAIPYGTKSQY------------ 111 Query: 120 RTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTES 160 + + RE + A M L K C E Sbjct: 112 --ILSVSRENLNKDLLTAAEKYPNVKMHFNHRLLK-CNPEE 149 >3CGD-A nrPDB Length = 480 Score = 34.4 bits (77), Expect = 0.14, Method: Composition-based stats. Identities = 39/262 (14%), Positives = 78/262 (29%), Gaps = 28/262 (10%) Query: 8 VVVGGGISGMAAAKLLHDS--GLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT- 64 V++GG +GM+AA + + NVV LE G Y+ + YV G Sbjct: 40 VIIGGDAAGMSAAMQIVRNDENANVVTLEK-----GEIYSYAQCGLPYVISGAIASTEKL 94 Query: 65 -QNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMD 123 + + G++ +EV ++ K + ++ + Sbjct: 95 IARNVKTFRDKYGIDAKVRHEVTKVDTEKK-----IVYAEHTKTKDVFEFSYDRL--LIA 147 Query: 124 DMGREIPSD-APWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEVSA 182 R + + + E + K T + T+ + E E + Sbjct: 148 TGVRPVMPEWEGRDLQGVHLLKTIPDAERILKTLETNKV-EDVTIIGGGAIGLEMAE-TF 205 Query: 183 LWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQTR 242 + V+ I + + G + + D + V Sbjct: 206 VELGKKVRMIERNDHIGTIYD--------GDMAEYIYKEADKHHIEILTNENVKAFKGNE 257 Query: 243 ENVLVETLNHEMYEAKYVISAI 264 VET + Y+A V+ ++ Sbjct: 258 RVEAVET-DKGTYKADLVLVSV 278 >5KXJ-A nrPDB Length = 557 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 11/30 (36%), Positives = 19/30 (63%), Gaps = 1/30 (3%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVL 33 CDV+++G G +G++ A L + V+VL Sbjct: 8 SCDVLIIGSGAAGLSLALRLAE-KHKVIVL 36 >2WOP-A nrPDB Length = 562 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 19/95 (20%), Positives = 33/95 (34%), Gaps = 8/95 (8%) Query: 13 GISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPT-QNRILRL 71 G +G+ A L + V GGRT+T R ++ D G ++ + R+ Sbjct: 75 GPAGLVPAPDLAEGPGEV-------SDGGRTWTYRLRRGLRYDDGTPITSDDVRHAVQRV 127 Query: 72 AKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPV 106 + L + L + P+R P Sbjct: 128 FAQDVLPGGPTYLIPLLDDPERPYPGPYRTDEPLR 162 >2GAG-B nrPDB Length = 405 Score = 34.0 bits (76), Expect = 0.15, Method: Composition-based stats. Identities = 21/60 (35%), Positives = 29/60 (48%), Gaps = 5/60 (8%) Query: 6 DVVVVGGGISGMAAAKLL-HDSGL-NVVVLEARDRVGG---RTYTLRNQKVKYVDLGGSY 60 D ++VGGG G+A A L + G+ NV VLE GG R T+ + + G Y Sbjct: 23 DAIIVGGGGHGLATAYFLAKNHGITNVAVLEKGWLAGGNMARNTTIIRSNYLWDESAGIY 82 >3II4-A nrPDB Length = 466 Score = 34.0 bits (76), Expect = 0.16, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 16/29 (55%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 DVVV+G G G AA GL+ ++E Sbjct: 7 DVVVLGAGPGGYVAAIRAAQLGLSTAIVE 35 >5XHU-A nrPDB Length = 329 Score = 33.6 bits (75), Expect = 0.21, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 26/53 (49%), Gaps = 1/53 (1%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGG 58 DV ++GGG G+ A L V+E ++GG+ +K+ D+GG Sbjct: 4 DVTIIGGGPIGLFTAFYCGMRELKTKVIEFLPKLGGKVSLFFPEKIIR-DIGG 55 >4Z2R-A nrPDB Length = 592 Score = 33.3 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 13/50 (26%), Positives = 26/50 (52%), Gaps = 2/50 (4%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLE--ARDRVGGRTYTLRNQ 49 S + DV++VG G +G +A LL G+ +++ G R++ + + Sbjct: 10 SAETDVLIVGAGPAGAMSATLLASLGIRSLMINRWRSTSPGPRSHIINQR 59 >1Y56-A nrPDB Length = 493 Score = 33.3 bits (74), Expect = 0.25, Method: Composition-based stats. Identities = 23/89 (25%), Positives = 37/89 (41%), Gaps = 12/89 (13%) Query: 402 FPPGILTQYGRVLRQPVDRIYFAGTETAT--HWSGYMEGAVEAGERAAREILHAMGKIPE 459 F G + + D IY AG+ + H++ Y+EG + IL G + Sbjct: 327 FRRGYYSPVLDEYHRIKDGIYVAGSAVSIKPHYANYLEGKL-----VGAYILKEFGYDAQ 381 Query: 460 DEIWQS-----EPESVDVPAQPITTTFLE 483 I++ EPES+ +P P+ LE Sbjct: 382 PCIYEEKLREYEPESLSIPRIPLDKFNLE 410 >4JNQ-A nrPDB Length = 345 Score = 33.3 bits (74), Expect = 0.31, Method: Composition-based stats. Identities = 24/94 (25%), Positives = 36/94 (38%), Gaps = 6/94 (6%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQN 66 V+V+G G +G AA + L VV+ A + GG+ + V+ Y P Q Sbjct: 29 VIVIGSGPAGYTAAIYAARAMLKPVVI-AGLQQGGQLMITTD-----VENYPGYAEPVQG 82 Query: 67 RILRLAKELGLETYKVNEVERLIHHVKGKSYPFR 100 + E V +I V+ PFR Sbjct: 83 PWMMEQMARQAENVGAQIVHDIITEVETTVRPFR 116 >3GDN-A nrPDB Length = 521 Score = 32.9 bits (73), Expect = 0.33, Method: Composition-based stats. Identities = 30/154 (19%), Positives = 46/154 (29%), Gaps = 13/154 (8%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 + D V+VGGG SG A L + V+VLE L Y Sbjct: 23 LEGSYDYVIVGGGTSGCPLAATLSE-KYKVLVLERGSLPTAYPNVLTADGFVY---NLQQ 78 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 + + R E G++ + V G + N Y W Sbjct: 79 EDDGKTPVERFVSEDGID--------NVRGRVLGGTSIINAGVYARANTSIYSASGVDWD 130 Query: 121 TMD-DMGREIPSDAPWKAPLAEEWDNMTMKELLD 153 + E D P ++ W ++T L+ Sbjct: 131 MDLVNQTYEWVEDTIVYKPNSQSWQSVTKTAFLE 164 >3GMC-A nrPDB Length = 415 Score = 32.9 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 16/53 (30%), Positives = 22/53 (41%), Gaps = 3/53 (5%) Query: 9 VVGGGISGMAAAKLLHDSGLNVVVLEARDRV---GGRTYTLRNQKVKYVDLGG 58 V GGG +G+ AA L +G +V + E + G Y N LG Sbjct: 52 VAGGGFAGLTAAIALKQNGWDVRLHEKSSELRAFGAGIYLWHNGLRVLEGLGA 104 >3L8K-A nrPDB Length = 466 Score = 32.9 bits (73), Expect = 0.34, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 18/36 (50%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 D+V++G G G+ A + G+ ++E DR Sbjct: 172 PQDMVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRA 207 Score = 29.4 bits (64), Expect = 4.1, Method: Composition-based stats. Identities = 48/381 (12%), Positives = 107/381 (28%), Gaps = 53/381 (13%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGR-----------TYTLRNQ 49 MS K DVVV+G G +G A L + NV++ + + +GG + Sbjct: 1 MSLKYDVVVIGAGGAGYHGAFRLAKAKYNVLMADPKGELGGNCLYSGCVPSKTVREVIQT 60 Query: 50 KVKYVDLGGSYVGPTQNRIL---RLAKELGLETYK--VNEVERLIHHVKGKSYPFRGPFP 104 + ++ + + + +EL + +K +++ E L + Sbjct: 61 AWRLTNIANVKIPLDFSTVQDRKDYVQELRFKQHKRNMSQYETLTFYKGYVKIKDPTHVI 120 Query: 105 PVWNPITYLDHNNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQL 164 + ++ + + P D K KL Q Sbjct: 121 VKTDEGKEIEAETRYMIIASGAETAKLRLPGVEYCLTSDDIFGYKTSFRKL------PQD 174 Query: 165 ATLFVNLCVTAETHEVSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDL 224 + + E + L + +I+ + + ++ + Sbjct: 175 MVIIGAGYIGLEIASIFRLMGVQTHIIEMLDRALITLED-----------QDIVNTLLSI 223 Query: 225 LGDRVKLERPVIYIDQ-TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRN 283 L +K PV + + + V + + +++ G + P +P Sbjct: 224 LKLNIKFNSPVTEVKKIKDDEYEVIYSTKDGSKKSIFTNSVVLAAGRR----PVIPEGAR 279 Query: 284 QMITRVPLGSVIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGF 343 ++ S+ K + E TM + + P + A M Sbjct: 280 EI-----GLSISKTGIVVDE----------TMKTNIPNVFATGDANGLAPYYHAAVRMSI 324 Query: 344 ILAHKARKLARLTKEERLKKL 364 A+ +K + Sbjct: 325 AAANNIMANGMPVDYVDVKSI 345 >1ZDL-A nrPDB Length = 517 Score = 32.9 bits (73), Expect = 0.39, Method: Composition-based stats. Identities = 56/388 (14%), Positives = 111/388 (28%), Gaps = 54/388 (13%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D++V+GGG G+A AK G V V + Y + + LGG+ V Sbjct: 34 DLLVIGGGSGGLACAKEAAQLGKKVAVAD---------YVEPSPRGTKWGLGGTCVNVGC 84 Query: 66 NRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWRTMDDM 125 ++L+H R W + HN W+TM + Sbjct: 85 IP------------------KKLMHQAALLGGMIRDAHHYGWEVAQPVQHN--WKTMAEA 124 Query: 126 GREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQ------LATLFVNLCVTAETHE 179 + W + + + + + + L V A Sbjct: 125 VQNHVKSLNWGHRVQLQDRKVKYFNIKASFVDEHTVRGVDKGGKATLLSAEHIVIATGGR 184 Query: 180 VSALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQV---SERIMDLLGDRVKL---ER 233 + + G T+ I + V G+ V + +G + Sbjct: 185 PRYPTQVKGALEYGITSDDIFWLKESPGKTLVVGASYVALECAGFLTGIGLDTTVMMRSI 244 Query: 234 PVIYIDQTRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGS 293 P+ DQ +++ E + +++ +P + LP + Q+ S Sbjct: 245 PLRGFDQQMSSLVTEHMESHG--TQFLKGCVPSHIK-------KLPTNQLQVTWEDH-AS 294 Query: 294 VIKCIVYYKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLA 353 + + W T ++ E+A ++ + K + + +A Sbjct: 295 GKEDTGTFDTVLWAIGRVPETRTLNLEKAGISTNPKNQKIIVDAQEATSVPHIYAIGDVA 354 Query: 354 RLTKEERLKKLCE---LYAKVLGSLEAL 378 E + L ++ G L Sbjct: 355 EGRPELTPTAIKAGKLLAQRLFGKSSTL 382 >2EEZ-A nrPDB Length = 369 Score = 32.9 bits (73), Expect = 0.40, Method: Composition-based stats. Identities = 23/90 (25%), Positives = 31/90 (34%), Gaps = 16/90 (17%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEAR--------DRVGGRTYTLRNQKVKYVD 55 VV++GGG G AAK+ G V +L+ D GGR TL + Sbjct: 166 PASVVILGGGTVGTNAAKIALGMGAQVTILDVNHKRLQYLDDVFGGRVITLTATEANIKK 225 Query: 56 --------LGGSYVGPTQNRILRLAKELGL 77 +G V + L L L Sbjct: 226 SVQHADLLIGAVLVPGAKAPKLVTRDMLSL 255 >4YKF-A nrPDB Length = 521 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 17/30 (56%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 V V+GGG SG+ AA L +V +LE Sbjct: 356 KRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 385 >1FL2-A nrPDB Length = 310 Score = 32.5 bits (72), Expect = 0.45, Method: Composition-based stats. Identities = 13/30 (43%), Positives = 17/30 (56%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 V V+GGG SG+ AA L +V +LE Sbjct: 145 KRVAVIGGGNSGVEAAIDLAGIVEHVTLLE 174 >3ICS-A nrPDB Length = 588 Score = 32.5 bits (72), Expect = 0.47, Method: Composition-based stats. Identities = 9/31 (29%), Positives = 16/31 (51%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 V+GGG G+ + L + G+ V ++E Sbjct: 187 PRHATVIGGGFIGVEMVENLRERGIEVTLVE 217 >1QO8-A nrPDB Length = 566 Score = 32.5 bits (72), Expect = 0.48, Method: Composition-based stats. Identities = 13/40 (32%), Positives = 21/40 (52%) Query: 2 SNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGG 41 S V+VVG G +G A+ +G NV++++ GG Sbjct: 119 SETTQVLVVGAGSAGFNASLAAKKAGANVILVDKAPFSGG 158 >1UKV-G nrPDB Length = 453 Score = 32.5 bits (72), Expect = 0.50, Method: Composition-based stats. Identities = 13/42 (30%), Positives = 23/42 (54%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLR 47 DV+V+G GI+ + LL G V+ ++ +D GG ++ Sbjct: 13 DVIVLGTGITECILSGLLSVDGKKVLHIDKQDHYGGEAASVT 54 >4H7U-A nrPDB Length = 602 Score = 32.5 bits (72), Expect = 0.53, Method: Composition-based stats. Identities = 13/31 (41%), Positives = 19/31 (61%), Gaps = 1/31 (3%) Query: 6 DVVVVGGGISGMAAAKLLHD-SGLNVVVLEA 35 D +V GGG +G+ A L + S V+V+EA Sbjct: 42 DFIVAGGGTAGLVVASRLSENSNWKVLVIEA 72 >5XMJ-A nrPDB Length = 627 Score = 32.1 bits (71), Expect = 0.60, Method: Composition-based stats. Identities = 19/84 (22%), Positives = 36/84 (42%), Gaps = 3/84 (3%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 DV+ +GG ++G A +GL ++L R+++ Q LG + +G Sbjct: 7 DVLCIGGALAGERVAVEASMAGLKTIML--SLVPPRRSHSSAAQGGMQAALGNAIMGDGD 64 Query: 66 NRILRLAKEL-GLETYKVNEVERL 88 + + A + G + EV R+ Sbjct: 65 SPDVHFADTVKGSDWGCDQEVARI 88 >3G5Q-A nrPDB Length = 443 Score = 32.1 bits (71), Expect = 0.69, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 18/32 (56%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDR 38 V VVG G++G AA L G+ V + E R + Sbjct: 4 VNVVGAGLAGSEAAWTLLRLGVPVRLFEMRPK 35 >5ER0-A nrPDB Length = 518 Score = 31.7 bits (70), Expect = 0.78, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 18/35 (51%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 + V+G G G A+ +G +V +++A RV Sbjct: 198 KRITVIGAGYIGAELAEAYSTTGHDVTLIDAMARV 232 >4Z25-A nrPDB Length = 652 Score = 31.3 bits (69), Expect = 0.92, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 19/34 (55%), Gaps = 1/34 (2%) Query: 6 DVVVVGGGISGMAAAKLLHD-SGLNVVVLEARDR 38 D+V++G G +G A L S + +++LEA Sbjct: 8 DIVIIGAGAAGSLLAHYLARFSNMKIILLEAGHS 41 >2QAE-A nrPDB Length = 468 Score = 31.3 bits (69), Expect = 0.95, Method: Composition-based stats. Identities = 10/31 (32%), Positives = 16/31 (51%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 +VV+GGG+ G+ + G V V+E Sbjct: 174 PKTMVVIGGGVIGLELGSVWARLGAEVTVVE 204 >4U2L-A nrPDB Length = 510 Score = 31.3 bits (69), Expect = 0.97, Method: Composition-based stats. Identities = 10/48 (20%), Positives = 19/48 (39%), Gaps = 5/48 (10%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYV 54 VV+G G +A L ++G+ ++LE G+ + Sbjct: 8 AVVIGTGYGAAVSALRLGEAGVQTLMLEM-----GQLWNQPGPDGNIF 50 >2YR5-A nrPDB Length = 721 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 20/85 (23%), Positives = 35/85 (41%), Gaps = 9/85 (10%) Query: 407 LTQYGRVLRQPVDRIYFAGTETATHWSGYMEGAVEAGE--------RAAREILHAMGKIP 458 + L +D +F +++ +H G++EGA + RA R + A+ Sbjct: 632 FRYHTHALAASLDNRFFIASDSYSHLGGWLEGAFMSALNAVAGLIVRANRGDVSALSTEA 691 Query: 459 EDEIWQSEPESVDVPAQPITTTFLE 483 + P V VPA + T+ LE Sbjct: 692 RPLVIGLRP-VVKVPAAELATSQLE 715 >3HDH-A nrPDB Length = 302 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 20/35 (57%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 V V+GGG+ G A++ +G VV+++ + + Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI 50 >1F14-A nrPDB Length = 310 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 10/35 (28%), Positives = 20/35 (57%) Query: 5 CDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 V V+GGG+ G A++ +G VV+++ + + Sbjct: 16 KHVTVIGGGLMGAGIAQVAAATGHTVVLVDQTEDI 50 >3O0H-A nrPDB Length = 484 Score = 31.3 bits (69), Expect = 1.0, Method: Composition-based stats. Identities = 11/34 (32%), Positives = 17/34 (50%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 +V+VGGG G+ A + H G+ +L D Sbjct: 191 PKSIVIVGGGYIGVEFANIFHGLGVKTTLLHRGD 224 >1GPE-A nrPDB Length = 587 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 10/30 (33%), Positives = 20/30 (66%), Gaps = 1/30 (3%) Query: 6 DVVVVGGGISGMAAAKLLHDSG-LNVVVLE 34 D ++ GGG++G+ A L ++ + V+V+E Sbjct: 26 DYIIAGGGLTGLTVAAKLTENPKIKVLVIE 55 >3RED-A nrPDB Length = 521 Score = 31.3 bits (69), Expect = 1.1, Method: Composition-based stats. Identities = 28/160 (17%), Positives = 46/160 (28%), Gaps = 13/160 (8%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 + D V+VGGG SG A L + V+VLE L + Y Sbjct: 23 LEGSYDYVIVGGGTSGCPLAATLSE-KYKVLVLERGTLPTAYPNLLTSDGFIY---NLQQ 78 Query: 61 VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR 120 Q + R G++ + V G + N + W Sbjct: 79 EDDGQTPVERFVSGDGID--------DVRGRVLGGTSMINAGVYARANTKIFSASGIEWD 130 Query: 121 TMD-DMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTE 159 + + D P + W ++T L+ + Sbjct: 131 MDLVNQTYDWVEDTIVYKPDKQAWQSLTKTAFLEAGVLPD 170 >2NVK-X nrPDB Length = 488 Score = 30.9 bits (68), Expect = 1.3, Method: Composition-based stats. Identities = 12/29 (41%), Positives = 19/29 (65%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLE 34 D++V+GGG +G+A AK +G V L+ Sbjct: 11 DLIVIGGGSAGLACAKEAVLNGARVACLD 39 >3D8X-A nrPDB Length = 326 Score = 30.9 bits (68), Expect = 1.4, Method: Composition-based stats. Identities = 7/30 (23%), Positives = 14/30 (46%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEA 35 V ++G G + AA L + + ++ E Sbjct: 12 KVTIIGSGPAAHTAAIYLARAEIKPILYEG 41 >5OC1-A nrPDB Length = 565 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 16/31 (51%), Positives = 22/31 (70%), Gaps = 1/31 (3%) Query: 6 DVVVVGGGISG-MAAAKLLHDSGLNVVVLEA 35 D VVVG G +G + AA+L D ++V+VLEA Sbjct: 3 DYVVVGAGNAGNVVAARLTEDPDVSVLVLEA 33 >6H3G-A nrPDB Length = 651 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 19/62 (30%), Positives = 28/62 (45%), Gaps = 11/62 (17%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSG--LNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY 60 + DV+V GGG +G A L + L V+++E GG N+ +V G Y Sbjct: 5 EEVDVIVCGGGPAGCVVAGRLAYADPTLKVMLIE-----GG----ANNRDDPWVYRPGIY 55 Query: 61 VG 62 V Sbjct: 56 VR 57 >5VT6-A nrPDB Length = 269 Score = 30.9 bits (68), Expect = 1.5, Method: Composition-based stats. Identities = 17/53 (32%), Positives = 24/53 (45%), Gaps = 4/53 (7%) Query: 5 CDVVVVGGGISGMAAA--KLLHDSGLNVVV--LEARDRVGGRTYTLRNQKVKY 53 V V GG+ G+ AA + LHD+G+ V V E D V R+ + Sbjct: 25 KRVAFVTGGMGGLGAAISRRLHDAGMAVAVSHSERNDHVSTWLMHERDAGRDF 77 >5IUJ-C nrPDB Length = 139 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 17/28 (60%) Query: 13 GISGMAAAKLLHDSGLNVVVLEARDRVG 40 G +G+ AA+ L D+G +++L R G Sbjct: 63 GKTGLEAAEELKDTGCKIIILTTFARPG 90 >4LDZ-A nrPDB Length = 203 Score = 30.6 bits (67), Expect = 1.6, Method: Composition-based stats. Identities = 10/28 (35%), Positives = 17/28 (60%) Query: 13 GISGMAAAKLLHDSGLNVVVLEARDRVG 40 G +G+ AA+ L D+G +++L R G Sbjct: 63 GKTGLEAAEELKDTGCKIIILTTFARPG 90 >6DU7-A nrPDB Length = 448 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 10/36 (27%), Positives = 16/36 (44%) Query: 4 KCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 V ++G G + A +LH G+ + RDR Sbjct: 166 PESVAILGAGYIAVELAGVLHTFGVKTDLFVRRDRP 201 >2CUL-A nrPDB Length = 232 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 11/27 (40%), Positives = 15/27 (55%) Query: 7 VVVVGGGISGMAAAKLLHDSGLNVVVL 33 V++VG G SG A L G+ V +L Sbjct: 6 VLIVGAGFSGAETAFWLAQKGVRVGLL 32 >3IWA-A nrPDB Length = 472 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 13/35 (37%), Positives = 20/35 (57%), Gaps = 1/35 (2%) Query: 6 DVVVVGGGISGMAAAKLLHDS-GLNVVVLEARDRV 39 V+VGGG G+ A L D G++ V+E D++ Sbjct: 161 KAVIVGGGFIGLEMAVSLADMWGIDTTVVELADQI 195 >3CP2-A nrPDB Length = 649 Score = 30.6 bits (67), Expect = 1.7, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 41/124 (33%), Gaps = 15/124 (12%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 + DV+++GGG +G AA G ++L T + + + G Sbjct: 25 DPFDVIIIGGGHAGTEAAMAAARMGQQTLLL-----------THNIDTLGQMSCNPAIGG 73 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT-YLDHNNFWRT 121 + +++ LG K + + + S +GP + + RT Sbjct: 74 IGKGHLVKEVDALGGLMAKAIDQAGIQFRILNAS---KGPAVRATRAQADRVLYRQAVRT 130 Query: 122 MDDM 125 + Sbjct: 131 ALEN 134 >5EB4-A nrPDB Length = 532 Score = 30.6 bits (67), Expect = 1.8, Method: Composition-based stats. Identities = 18/78 (23%), Positives = 28/78 (35%), Gaps = 4/78 (5%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVGPTQ 65 D +V+GGG SG A L + V++LE TL Y + Sbjct: 28 DYIVIGGGTSGCPLAATLSE-KYKVLLLERGTIATEYPNTLTADGFAY---NLQQQDDGK 83 Query: 66 NRILRLAKELGLETYKVN 83 + R E G++ + Sbjct: 84 TPVERFVSEDGIDNVRAR 101 >2YVG-A nrPDB Length = 408 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 11/37 (29%), Positives = 22/37 (59%) Query: 8 VVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTY 44 ++VGGG+ G+ A +G++V ++E + R+ R Sbjct: 149 LIVGGGVIGLELAATARTAGVHVSLVETQPRLMSRAA 185 >3G05-A nrPDB Length = 576 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 20/124 (16%), Positives = 41/124 (33%), Gaps = 15/124 (12%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 + DV+++GGG +G AA G ++L T + + + G Sbjct: 31 DPFDVIIIGGGHAGTEAAMAAARMGQQTLLL-----------THNIDTLGQMSCNPAIGG 79 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT-YLDHNNFWRT 121 + +++ LG K + + + S +GP + + RT Sbjct: 80 IGKGHLVKEVDALGGLMAKAIDQAGIQFRILNAS---KGPAVRATRAQADRVLYRQAVRT 136 Query: 122 MDDM 125 + Sbjct: 137 ALEN 140 >4FK1-A nrPDB Length = 304 Score = 30.6 bits (67), Expect = 1.9, Method: Composition-based stats. Identities = 9/46 (19%), Positives = 19/46 (41%), Gaps = 3/46 (6%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKV 51 D V+G G +G+ A+ +L + + + + R +N Sbjct: 8 DCAVIGAGPAGLNASLVLGRARKQIALFDNNTN---RNRVTQNSHG 50 >4EIQ-A nrPDB Length = 549 Score = 30.6 bits (67), Expect = 2.0, Method: Composition-based stats. Identities = 13/32 (40%), Positives = 20/32 (62%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARD 37 DV+++GGG GMA A L + +V++A D Sbjct: 28 DVLILGGGPVGMALALDLAHRQVGHLVVDAGD 59 >2BC1-A nrPDB Length = 490 Score = 30.2 bits (66), Expect = 2.2, Method: Composition-based stats. Identities = 17/70 (24%), Positives = 24/70 (34%), Gaps = 9/70 (12%) Query: 223 DLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEA-KYVISAIPPTLGMKIHFNPPLPMM 281 + LG +V +E PV ID + V E +I A P LP + Sbjct: 103 ESLGAKVYMESPVQSIDYDAKTVTALVDGKNHVETYDKLIFATGS--------QPILPPI 154 Query: 282 RNQMITRVPL 291 + I L Sbjct: 155 KGAEIKEGSL 164 >5NA1-A nrPDB Length = 408 Score = 30.2 bits (66), Expect = 2.6, Method: Composition-based stats. Identities = 6/24 (25%), Positives = 13/24 (54%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDS 26 ++ V+V+G G +G+ L + Sbjct: 10 DRKKVLVLGAGYAGLQTVTKLQKA 33 >3OC4-A nrPDB Length = 452 Score = 29.8 bits (65), Expect = 3.0, Method: Composition-based stats. Identities = 12/39 (30%), Positives = 17/39 (43%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRV 39 + N V V+G G GM A L V V E+ + + Sbjct: 144 LENSQTVAVIGAGPIGMEAIDFLVKMKKTVHVFESLENL 182 >2WOV-A nrPDB Length = 495 Score = 29.8 bits (65), Expect = 3.4, Method: Composition-based stats. Identities = 27/134 (20%), Positives = 45/134 (33%), Gaps = 11/134 (8%) Query: 1 MSNKCDVVVVGGGISGMAAAKLLHD-SGLNVVVLEARDRVGGRTYTLRNQKVKYVDLG-- 57 MS D+VV+G G G+ A G V V++ + G Y V++G Sbjct: 4 MSKAFDLVVIGAGSGGLEAGWNAATLYGKRVAVVDVQTSHGPPFYAA--LGGTCVNVGCV 61 Query: 58 ---GSYVGPTQNRILRLAKELGLE---TYKVNEVERLIHHVKGKSYPFRGPFPPVWNPIT 111 G LR + G E + ++LI + ++N Sbjct: 62 PKKLMVTGAQYMDHLRESAGFGWEFDGSSVKANWKKLIAAKNEAVLDINKSYEGMFNDTE 121 Query: 112 YLDHNNFWRTMDDM 125 LD W +++ Sbjct: 122 GLDFFLGWGSLESK 135 >2HCS-A nrPDB Length = 595 Score = 29.4 bits (64), Expect = 3.5, Method: Composition-based stats. Identities = 33/187 (17%), Positives = 59/187 (31%), Gaps = 33/187 (17%) Query: 11 GGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLR----NQKVKYVDLG-----GSYV 61 GGG+ G+ L G ++ E R GGR Y + ++ DL + Sbjct: 196 GGGVEGLG----LQKLG--YILREVGTRPGGRIYADDTAGWDTRITRADLENEAKVLELL 249 Query: 62 GPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYP-------FRGPFPPVWNPITYLD 114 R+ R EL TY+ V+ + G++ RG V + Sbjct: 250 DGEHRRLARAIIEL---TYRHKVVKVMRPAADGRTVMDVISREDQRGSGQVVTYALNTFT 306 Query: 115 H--NNFWRTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLC 172 + R M+ G P D + ++ L + ++ + + C Sbjct: 307 NLAVQLVRMMEGEGVIGPDD----VEKLTKGKGPKVRTWLSENGEERLSRMAVS--GDDC 360 Query: 173 VTAETHE 179 V + Sbjct: 361 VVKPLDD 367 >4P5A-A nrPDB Length = 239 Score = 29.4 bits (64), Expect = 3.7, Method: Composition-based stats. Identities = 9/35 (25%), Positives = 19/35 (54%) Query: 42 RTYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELG 76 RT++ + +Y ++G ++ P R+LR + G Sbjct: 88 RTWSFNEESARYREVGAAFYVPDATRLLRQEGKPG 122 >2QA1-A nrPDB Length = 500 Score = 29.4 bits (64), Expect = 3.8, Method: Composition-based stats. Identities = 10/21 (47%), Positives = 13/21 (61%) Query: 7 VVVVGGGISGMAAAKLLHDSG 27 V+VVG G +GM A L +G Sbjct: 14 VIVVGAGPAGMMLAGELRLAG 34 >1VRQ-A nrPDB Length = 964 Score = 29.4 bits (64), Expect = 4.2, Method: Composition-based stats. Identities = 18/56 (32%), Positives = 31/56 (55%), Gaps = 1/56 (1%) Query: 6 DVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYV 61 DV+VVG G +G+AAA+ SG V++L+ R GG +++ +D ++ Sbjct: 129 DVLVVGAGPAGLAAAREASRSGARVMLLDERPEAGGTLREASGEQIDGID-AAQWI 183 >5O32-I nrPDB Length = 244 Score = 28.6 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 23/155 (14%), Positives = 48/155 (30%), Gaps = 20/155 (12%) Query: 43 TYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGP 102 + LR K + + V + R+ E V+R+I H + + Sbjct: 40 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEY---------VDRIIFHENYNAGTY--- 87 Query: 103 FPPVWNPITYLDHNNFW-RTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESA 161 N I ++ + ++ R IP+ PW L + D + + Sbjct: 88 ----QNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV- 142 Query: 162 KQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTT 196 + + + + + + F +C GT Sbjct: 143 --FSLQWGEVKLISNCSKFYGNRFYEKEMECAGTY 175 >2XRC-A nrPDB Length = 565 Score = 28.6 bits (62), Expect = 6.1, Method: Composition-based stats. Identities = 23/155 (14%), Positives = 48/155 (30%), Gaps = 20/155 (12%) Query: 43 TYTLRNQKVKYVDLGGSYVGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGP 102 + LR K + + V + R+ E V+R+I H + + Sbjct: 361 AHCLRASKTHRYQIWTTVVDWIHPDLKRIVIEY---------VDRIIFHENYNAGTY--- 408 Query: 103 FPPVWNPITYLDHNNFW-RTMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESA 161 N I ++ + ++ R IP+ PW L + D + + Sbjct: 409 ----QNDIALIEMKKDGNKKDCELPRSIPACVPWSPYLFQPNDTCIVSGWGREKDNERV- 463 Query: 162 KQLATLFVNLCVTAETHEVSALWFLWYVKQCGGTT 196 + + + + + + F +C GT Sbjct: 464 --FSLQWGEVKLISNCSKFYGNRFYEKEMECAGTY 496 >4BK3-A nrPDB Length = 424 Score = 28.2 bits (61), Expect = 8.2, Method: Composition-based stats. Identities = 6/40 (15%), Positives = 13/40 (32%) Query: 222 MDLLGDRVKLERPVIYIDQTRENVLVETLNHEMYEAKYVI 261 G + V + + +V T + +EA + Sbjct: 121 ARAAGAELHTGVTVTDVITEGDKAIVSTDDGRTHEADIAL 160 >2ZXH-A nrPDB Length = 637 Score = 28.2 bits (61), Expect = 8.7, Method: Composition-based stats. Identities = 21/126 (16%), Positives = 42/126 (33%), Gaps = 19/126 (15%) Query: 3 NKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSYVG 62 ++ DVVV+GGG +G+ AA G + L + + + G Sbjct: 26 DEFDVVVIGGGHAGIEAALAAARMGAKTAMF-----------VLNADTIGQMSCNPAIGG 74 Query: 63 PTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLD---HNNFW 119 + ++R LG E K + + + V +P D + + Sbjct: 75 IAKGIVVREIDALGGEMGKAIDQTGIQFKMLNTR-----KGKAVQSPRAQADKKRYREYM 129 Query: 120 RTMDDM 125 + + + Sbjct: 130 KKVCEN 135 Database: ../databases/nrPDB-GO_2019.06.18_sequences.fasta Posted date: Jan 3, 2023 9:05 PM Number of letters in database: 10,336,785 Number of sequences in database: 36,641 Lambda K H 0.309 0.121 0.292 Lambda K H 0.267 0.0370 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 17,007,817 Number of Sequences: 36641 Number of extensions: 673847 Number of successful extensions: 2897 Number of sequences better than 10.0: 269 Number of HSP's better than 10.0 without gapping: 344 Number of HSP's successfully gapped in prelim test: 81 Number of HSP's that attempted gapping in prelim test: 2285 Number of HSP's gapped (non-prelim): 565 length of query: 520 length of database: 10,336,785 effective HSP length: 101 effective length of query: 419 effective length of database: 6,636,044 effective search space: 2780502436 effective search space used: 2780502436 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.3 bits) S2: 61 (28.3 bits)